# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF1725 PF08333.9 T312618_1 - 0.053 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) DUF2619 PF10942.6 T187838_3 - 0.058 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2619) DUF1725 PF08333.9 T215632_1 - 3.4e-07 29.6 1.3 3.4e-07 29.6 1.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T215632_2 - 3.6e-05 23.2 0.1 0.0017 17.8 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Toxin_18 PF08087.9 T242494_3 - 7.4 6.5 8.3 0.52 10.2 2.1 2.1 2 0 0 2 2 2 0 Conotoxin O-superfamily CENP-B_N PF04218.11 T332413_2 - 0.078 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF3545 PF12065.6 T356019_1 - 0.032 14.1 1.4 0.43 10.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) RVT_1 PF00078.25 T266890_3 - 5e-13 48.9 0.0 9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Wbp11 PF09429.8 T094028_2 - 0.39 11.0 8.7 0.82 10.0 8.7 1.5 1 0 0 1 1 1 0 WW domain binding protein 11 DUF834 PF05754.12 T255391_2 - 0.028 14.5 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF834) DUF1725 PF08333.9 T106370_1 - 0.00074 19.0 0.4 0.0018 17.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF3704 PF12488.6 T373849_3 - 0.12 11.9 4.6 0.29 10.7 2.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) PetM PF08041.9 T285309_2 - 0.035 13.5 2.0 0.082 12.4 2.0 1.6 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 DUF4501 PF14946.4 T048240_1 - 0.3 11.0 1.8 0.44 10.5 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) DUF4939 PF16297.3 T158045_1 - 0.034 13.9 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DUF4939 PF16297.3 T158045_2 - 9.4e-11 41.5 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) UvrB PF12344.6 T102696_1 - 0.096 12.4 0.7 0.16 11.7 0.7 1.2 1 0 0 1 1 1 0 Ultra-violet resistance protein B Transposase_22 PF02994.12 T190842_1 - 3.4e-45 154.4 2.6 4.6e-45 153.9 2.6 1.1 1 0 0 1 1 1 1 L1 transposable element Transposase_22 PF02994.12 T190842_2 - 2.4e-57 194.3 15.9 3.7e-57 193.7 15.9 1.2 1 0 0 1 1 1 1 L1 transposable element Seryl_tRNA_N PF02403.20 T190842_2 - 0.0045 17.1 8.0 0.0079 16.3 8.0 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Med2 PF11214.6 T190842_2 - 0.015 15.3 4.8 0.089 12.8 1.5 2.6 2 0 0 2 2 2 0 Mediator complex subunit 2 ATG16 PF08614.9 T190842_2 - 0.016 15.3 11.1 0.03 14.4 11.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.4 T190842_2 - 0.026 13.7 11.4 0.046 13.0 11.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding KLRAQ PF10205.7 T190842_2 - 0.044 13.9 6.3 0.14 12.2 6.3 1.9 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein IncA PF04156.12 T190842_2 - 0.052 13.2 11.0 0.097 12.3 11.0 1.3 1 0 0 1 1 1 0 IncA protein Syntaxin-6_N PF09177.9 T190842_2 - 0.062 13.7 6.1 0.13 12.7 6.1 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Spectrin PF00435.19 T190842_2 - 0.069 13.5 5.2 0.13 12.6 5.2 1.4 1 0 0 1 1 1 0 Spectrin repeat TBPIP PF07106.11 T190842_2 - 0.08 12.6 13.2 0.02 14.6 7.7 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.10 T190842_2 - 0.15 11.3 12.2 0.24 10.6 12.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1664 PF07889.10 T190842_2 - 0.32 10.9 2.2 0.59 10.0 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.14 T190842_2 - 0.37 11.1 6.6 1 9.7 4.9 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Mnd1 PF03962.13 T190842_2 - 0.5 10.1 9.4 0.93 9.2 9.4 1.3 1 0 0 1 1 1 0 Mnd1 family DUF342 PF03961.11 T190842_2 - 0.66 8.4 6.6 0.18 10.3 3.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF812 PF05667.9 T190842_2 - 0.83 8.3 15.3 1.2 7.8 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.10 T190842_2 - 1.9 8.4 9.7 4.9 7.1 9.7 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.7 T190842_2 - 5.8 7.0 14.7 11 6.1 14.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 RNA_pol_Rpc4 PF05132.12 T224191_1 - 0.96 9.8 14.4 1.8 8.9 14.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Coilin_N PF15862.3 T224191_1 - 3.3 7.3 16.8 8.2 6.1 16.8 1.6 1 0 0 1 1 1 0 Coilin N-terminus DDHD PF02862.15 T224191_1 - 4 7.4 11.8 6.9 6.6 11.8 1.2 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.12 T224191_2 - 0.34 11.2 15.5 0.025 14.9 8.9 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF1510 PF07423.9 T224191_2 - 3.1 7.0 18.3 6.4 6.0 18.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Eapp_C PF10238.7 T224191_2 - 4.2 7.3 15.9 13 5.8 15.9 1.8 1 0 0 1 1 1 0 E2F-associated phosphoprotein RVT_1 PF00078.25 T224191_3 - 0.0004 19.8 0.0 0.00075 18.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T224191_3 - 0.048 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T176715_3 - 1.6e-13 50.2 0.5 2.9e-13 49.3 0.5 1.3 1 0 0 1 1 1 1 L1 transposable element SVM_signal PF12113.6 T281975_2 - 0.16 11.7 0.7 0.32 10.8 0.7 1.4 1 0 0 1 1 1 0 SVM protein signal sequence Transposase_22 PF02994.12 T136208_2 - 0.00012 21.0 0.1 0.00019 20.3 0.1 1.3 1 0 0 1 1 1 1 L1 transposable element PAN_1 PF00024.24 T011328_1 - 0.11 12.4 1.5 0.18 11.7 1.5 1.3 1 0 0 1 1 1 0 PAN domain TLV_coat PF00429.17 T225710_1 - 0.00016 20.4 1.5 0.00025 19.7 1.5 1.2 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) IGR PF09597.8 T355657_1 - 0.024 14.6 0.0 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 IGR protein motif DUF359 PF04019.10 T094281_1 - 0.19 11.2 4.5 0.38 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF359) DUF1725 PF08333.9 T083965_3 - 0.00096 18.6 0.7 0.0018 17.7 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_1 PF01359.16 T081620_1 - 0.00018 21.2 0.9 0.0004 20.0 0.9 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) Transposase_1 PF01359.16 T081620_3 - 1.6e-21 75.8 0.1 2.7e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) PEPcase PF00311.15 T198847_1 - 0.21 9.5 0.7 0.28 9.0 0.7 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Mit_proteolip PF08039.9 T201244_1 - 0.83 9.9 7.3 2.2 8.5 7.3 1.7 1 0 0 1 1 1 0 Mitochondrial proteolipid YHS PF04945.11 T251985_3 - 0.24 11.4 1.7 6 6.9 1.6 2.4 2 0 0 2 2 2 0 YHS domain ICAM_N PF03921.12 T228081_3 - 0.44 10.1 12.4 6.6 6.4 0.1 5.1 4 1 0 4 4 4 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF3915 PF13054.4 T375490_2 - 2.9 7.8 4.9 5 7.0 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DDE_1 PF03184.17 T344129_3 - 0.00035 20.1 0.4 0.00054 19.5 0.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease EMI PF07546.11 T087626_2 - 6.7 7.4 7.3 5.4 7.7 0.1 3.2 3 0 0 3 3 3 0 EMI domain Exo_endo_phos_2 PF14529.4 T265287_1 - 3.7e-09 36.3 1.0 6e-09 35.7 1.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1725 PF08333.9 T265287_1 - 0.0005 19.5 0.3 0.001 18.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Exo_endo_phos PF03372.21 T265287_1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Atrophin-1 PF03154.13 T190687_1 - 0.5 8.4 21.0 0.82 7.8 21.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF1725 PF08333.9 T308094_3 - 0.00011 21.6 1.0 0.00021 20.7 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF3704 PF12488.6 T160821_1 - 0.0075 15.8 2.3 0.016 14.7 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3704) Mit_proteolip PF08039.9 T058452_2 - 0.011 16.0 2.8 0.023 14.9 2.8 1.5 1 0 0 1 1 1 0 Mitochondrial proteolipid DUF3648 PF12364.6 T161327_2 - 0.37 10.9 4.7 0.64 10.1 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) GPAT_N PF14829.4 T383634_2 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal IN_DBD_C PF00552.19 T096768_2 - 0.016 14.4 0.2 0.029 13.6 0.2 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain TLV_coat PF00429.17 T373080_1 - 9.1e-09 34.4 0.5 1.2e-07 30.7 0.4 2.0 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) SART-1 PF03343.11 T373080_2 - 0.24 9.8 9.5 0.33 9.3 9.5 1.1 1 0 0 1 1 1 0 SART-1 family Gag_p30 PF02093.14 T373080_3 - 2e-08 33.9 0.0 3.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Gag P30 core shell protein RNase_H PF00075.22 T373080_3 - 0.1 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 RNase H DUF1725 PF08333.9 T094288_2 - 4.8e-06 25.9 0.6 8.9e-06 25.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T097484_2 - 5.2e-36 124.1 1.0 7.6e-36 123.6 1.0 1.1 1 0 0 1 1 1 1 L1 transposable element WASH_WAHD PF11945.6 T074033_2 - 0.0031 17.0 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex OST3_OST6 PF04756.11 T349140_3 - 0.017 14.3 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TAF1_subA PF14929.4 T110326_2 - 0.18 11.0 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A DUF1725 PF08333.9 T357065_3 - 0.0049 16.3 0.6 0.011 15.3 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T377977_1 - 3e-40 138.1 4.6 4.7e-40 137.4 4.6 1.2 1 0 0 1 1 1 1 L1 transposable element DUF1725 PF08333.9 T377977_2 - 3.3e-08 32.8 1.3 8.4e-08 31.5 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Exo_endo_phos PF03372.21 T377977_2 - 0.00068 19.7 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.25 T377977_3 - 1.5e-07 31.1 0.2 2.6e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T355056_1 - 1.4e-07 30.8 0.1 3.5e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) zf-CCHC PF00098.21 T080984_1 - 0.0023 17.8 4.3 0.0023 17.8 4.3 3.2 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_5 PF14787.4 T080984_1 - 2.2 7.9 16.3 3.2 7.4 4.3 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Gag_p30 PF02093.14 T080984_2 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein CCDC92 PF14916.4 T133836_1 - 0.092 12.4 1.0 0.17 11.6 1.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF1725 PF08333.9 T280380_1 - 0.011 15.3 0.7 0.022 14.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) DM4_12 PF07841.11 T294568_2 - 4.2 8.0 15.6 12 6.6 0.0 4.2 1 1 4 5 5 5 0 DM4/DM12 family Toxin_18 PF08087.9 T356275_2 - 0.032 14.1 0.7 0.064 13.1 0.7 1.5 1 0 0 1 1 1 0 Conotoxin O-superfamily Peptidase_S49_N PF08496.8 T188472_3 - 4.1 7.3 5.6 6.7 6.6 5.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EPF PF17181.2 T043400_2 - 0.16 11.9 2.0 0.39 10.6 2.0 1.6 1 0 0 1 1 1 0 Epidermal patterning factor proteins DUF1725 PF08333.9 T043400_3 - 0.0014 18.1 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Ribosomal_L19e PF01280.18 T043400_3 - 0.057 13.3 0.1 0.096 12.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L19e Transposase_1 PF01359.16 T081618_1 - 2.3e-21 75.3 0.1 3.9e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) Transposase_1 PF01359.16 T081618_2 - 0.00027 20.6 0.9 0.00055 19.6 0.9 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) zf-CCHC PF00098.21 T346532_1 - 9.5e-05 22.2 1.8 0.00027 20.7 1.8 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.4 T346532_1 - 0.086 12.7 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle CD45 PF12567.6 T325186_1 - 1.2 9.1 7.7 1.1 9.3 2.4 3.1 2 0 0 2 2 2 0 Leukocyte receptor CD45 NR_Repeat PF14046.4 T072450_2 - 0.42 10.7 4.2 5.9 7.0 0.6 2.9 3 0 0 3 3 3 0 Nuclear receptor repeat Med19 PF10278.7 T325036_2 - 0.66 9.8 5.0 1.3 8.7 5.0 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Transposase_22 PF02994.12 T101924_1 - 1.2e-28 99.9 0.0 2.1e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 L1 transposable element DUF1725 PF08333.9 T101924_2 - 5.3e-12 44.9 3.8 1e-05 24.9 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T101924_2 - 0.00049 19.5 0.0 0.00084 18.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_22 PF02994.12 T101924_3 - 9.3e-28 97.0 14.3 2.4e-27 95.6 14.3 1.6 1 1 0 1 1 1 1 L1 transposable element DUF1725 PF08333.9 T101924_3 - 5.2e-06 25.8 1.4 1.2e-05 24.6 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Gag_MA PF01140.17 T150763_3 - 0.00013 21.6 0.2 0.00025 20.6 0.2 1.4 1 0 0 1 1 1 1 Matrix protein (MA), p15 DUF3704 PF12488.6 T265172_2 - 0.22 11.1 2.3 0.66 9.5 2.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) DUF1725 PF08333.9 T107945_3 - 0.0015 18.0 1.3 0.0015 18.0 1.3 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1725) LRRCT PF01463.22 T362105_2 - 7.9 7.2 9.2 29 5.4 0.6 4.3 4 0 0 4 4 4 0 Leucine rich repeat C-terminal domain DUF4498 PF14926.4 T306302_3 - 0.087 12.0 0.2 0.15 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) SPX PF03105.17 T035770_1 - 2.1 8.1 4.3 3.6 7.3 4.3 1.3 1 0 0 1 1 1 0 SPX domain DUF1725 PF08333.9 T153414_2 - 1.2e-07 31.0 0.4 3e-07 29.8 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T060747_2 - 3.1e-05 23.4 0.4 3.1e-05 23.4 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) LCE PF14672.4 T060747_2 - 5.5 7.6 14.7 1.7 9.2 10.4 2.5 2 0 0 2 2 2 0 Late cornified envelope Myc_N PF01056.16 T341486_2 - 8.5 6.0 11.4 14 5.3 11.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region TMEM119 PF15724.3 T341486_3 - 0.18 11.7 2.4 0.52 10.2 2.4 1.7 1 0 0 1 1 1 0 TMEM119 family Interferon PF00143.17 T356415_1 - 6.2e-09 36.1 0.2 3.9e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 Interferon alpha/beta domain NICE-1 PF15845.3 T092451_3 - 0.9 10.2 6.3 7.5 7.3 3.1 2.6 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family DHODB_Fe-S_bind PF10418.7 T261303_2 - 3.8 7.2 5.3 22 4.8 1.9 2.5 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Rrn6 PF10214.7 T047715_1 - 0.23 9.7 2.1 0.3 9.3 2.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor YqzE PF14038.4 T047715_1 - 0.27 11.1 5.2 0.58 10.1 5.2 1.5 1 0 0 1 1 1 0 YqzE-like protein zf-CCHC PF00098.21 T013868_2 - 0.051 13.5 1.7 0.12 12.4 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Gag_p30 PF02093.14 T013868_3 - 9.5e-08 31.7 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Gag P30 core shell protein Transposase_1 PF01359.16 T081624_1 - 2.6e-21 75.1 0.1 4.7e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) Transposase_1 PF01359.16 T081624_2 - 0.00031 20.4 0.9 0.00066 19.4 0.9 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) Potassium_chann PF11404.6 T062211_1 - 4.5 7.0 5.3 1.2 8.9 1.4 2.1 2 0 0 2 2 2 0 Potassium voltage-gated channel DUF1725 PF08333.9 T354862_1 - 0.0014 18.0 0.1 0.0053 16.3 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) FAM27 PF15832.3 T011204_2 - 6.3 7.3 14.2 13 6.2 0.5 2.8 2 0 0 2 2 2 0 FAM27 D and E protein family RVT_1 PF00078.25 T271203_2 - 5e-14 52.2 0.7 2.3e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.21 T271203_2 - 0.015 15.4 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF1725 PF08333.9 T271203_3 - 0.28 10.8 6.3 0.012 15.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T054281_3 - 1.1e-08 34.4 0.7 2.2e-08 33.4 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T296982_3 - 5.3e-07 29.0 1.1 1.5e-06 27.6 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) Orthopox_B11R PF07033.9 T296982_3 - 0.39 10.4 3.0 0.15 11.7 0.2 1.7 2 0 0 2 2 2 0 Orthopoxvirus B11R protein McyA_C PF12593.6 T121207_1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Microcystin synthetase C terminal DUF1725 PF08333.9 T005596_2 - 0.071 12.7 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T204244_3 - 3.3e-21 75.4 2.1 6.4e-21 74.5 2.1 1.4 1 1 0 1 1 1 1 L1 transposable element DUF3070 PF11270.6 T238277_1 - 0.01 15.9 1.7 0.033 14.3 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) DUF1725 PF08333.9 T253561_1 - 1.8e-05 24.1 3.8 3.6e-05 23.1 3.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T348145_2 - 1.4e-07 30.8 0.5 2.9e-07 29.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) ESR1_C PF12743.5 T152285_2 - 0.15 11.8 2.0 0.23 11.1 2.0 1.2 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal PRK PF00485.16 T206322_3 - 0.17 11.5 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GHBP PF12772.5 T006205_2 - 0.043 13.2 0.3 0.062 12.7 0.3 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding Atrophin-1 PF03154.13 T171580_3 - 0.023 12.9 14.3 0.031 12.4 14.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 T171580_3 - 1.5 8.7 9.7 2.8 7.8 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) IgG_binding_B PF01378.15 T276390_3 - 0.16 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 B domain DUF1725 PF08333.9 T285326_2 - 0.00081 18.8 1.0 0.00081 18.8 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) Phage_holin_1 PF04531.11 T325172_2 - 1.1 9.8 4.6 1.8 9.0 4.6 1.4 1 0 0 1 1 1 0 Bacteriophage holin rve PF00665.24 T325172_3 - 0.042 13.9 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DUF1725 PF08333.9 T208774_2 - 0.0062 16.0 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T056116_2 - 0.039 13.5 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Gag_MA PF01140.17 T184948_1 - 3.3e-12 46.1 2.1 3.3e-12 46.1 2.1 1.6 2 0 0 2 2 2 1 Matrix protein (MA), p15 DUF1725 PF08333.9 T184948_1 - 1.6e-06 27.4 1.0 3.8e-06 26.3 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) MIP-T3 PF10243.7 T184948_1 - 0.42 9.1 19.0 0.65 8.5 19.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HERV-K_REC PF15695.3 T376524_2 - 2.2e-05 24.3 0.7 4.3e-05 23.4 0.7 1.4 1 0 0 1 1 1 1 Rec (regulator of expression encoded by corf) of HERV-K-113 HTH_1 PF00126.25 T376524_2 - 0.1 12.4 0.1 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HERV-K_env_2 PF13804.4 T376524_3 - 3.2e-05 23.6 0.0 6.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Retro-transcribing viruses envelope glycoprotein Bowman-Birk_leg PF00228.18 T104030_1 - 0.062 13.5 0.5 0.15 12.3 0.5 1.7 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family Glyoxalase_4 PF13669.4 T384049_2 - 0.00092 19.4 2.7 6.1 7.1 0.1 3.4 3 1 0 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EB PF01683.16 T384049_2 - 0.78 9.9 4.7 7.5 6.8 0.6 2.4 1 1 1 2 2 2 0 EB module DUF2484 PF10658.7 T384049_3 - 0.14 12.4 0.1 7.6 6.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2484) DUF1725 PF08333.9 T263333_3 - 3.3e-07 29.6 1.0 6.8e-07 28.6 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T153317_3 - 5e-46 157.1 0.5 7.6e-46 156.5 0.5 1.2 1 0 0 1 1 1 1 L1 transposable element SR-25 PF10500.7 T064898_2 - 7.3 6.0 18.6 11 5.5 18.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.25 T160631_1 - 0.00016 21.1 0.1 0.00036 20.0 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T012152_1 - 0.00019 20.9 0.5 0.00049 19.6 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T145585_3 - 1.7e-08 33.7 1.7 3.7e-08 32.7 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) SLC3A2_N PF16028.3 T133906_1 - 0.32 10.4 2.4 0.79 9.2 2.4 1.6 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Transposase_22 PF02994.12 T016270_2 - 8e-09 34.7 0.7 1.4e-08 33.8 0.7 1.3 1 0 0 1 1 1 1 L1 transposable element zf-C3H1 PF10650.7 T366713_1 - 1.3 8.7 6.9 4.5 7.0 0.9 2.7 2 0 0 2 2 2 0 Putative zinc-finger domain PQ-loop PF04193.12 T287814_3 - 0.069 12.8 3.5 0.18 11.5 3.5 1.7 1 0 0 1 1 1 0 PQ loop repeat Transposase_22 PF02994.12 T017715_1 - 6.1e-08 31.8 0.1 7.9e-08 31.4 0.1 1.2 1 0 0 1 1 1 1 L1 transposable element Transposase_22 PF02994.12 T017715_3 - 3.8e-14 52.2 2.7 4.3e-14 52.0 2.7 1.1 1 0 0 1 1 1 1 L1 transposable element DUF3704 PF12488.6 T331231_1 - 0.068 12.7 3.5 0.15 11.6 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) RVP PF00077.18 T239418_2 - 0.0014 18.7 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Transposase_22 PF02994.12 T327748_2 - 1.7e-73 247.5 19.9 5.4e-64 216.2 5.7 2.4 2 0 0 2 2 2 2 L1 transposable element RVT_1 PF00078.25 T327748_3 - 1.1e-35 123.1 3.3 1.7e-35 122.4 3.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_22 PF02994.12 T327748_3 - 1.2e-22 80.2 2.9 1.9e-22 79.5 2.9 1.3 1 0 0 1 1 1 1 L1 transposable element DUF1725 PF08333.9 T327748_3 - 0.0028 17.1 0.1 0.0072 15.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Syntaxin-5_N PF11416.6 T164665_3 - 0.32 10.1 1.9 0.81 8.8 1.9 1.7 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain HTH_Tnp_Tc5 PF03221.14 T013944_1 - 2.2e-06 27.5 0.1 3.9e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.17 T013944_1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.17 T013944_3 - 2.2e-06 27.2 0.2 3.9e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Mit_proteolip PF08039.9 T378146_3 - 4.6 7.5 12.0 0.41 10.9 3.0 2.5 2 0 0 2 2 2 0 Mitochondrial proteolipid DUF1725 PF08333.9 T213652_1 - 3.2e-08 32.8 0.1 7.6e-08 31.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T042863_1 - 7.3e-23 80.9 0.2 1.2e-22 80.2 0.2 1.2 1 0 0 1 1 1 1 L1 transposable element RVT_1 PF00078.25 T042863_1 - 1e-05 25.1 0.1 4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IncA PF04156.12 T042863_3 - 2.8 7.6 6.6 4.6 6.8 6.6 1.3 1 0 0 1 1 1 0 IncA protein DUF1725 PF08333.9 T247662_3 - 0.00021 20.7 0.2 0.00041 19.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) IN_DBD_C PF00552.19 T031712_1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Integrase DNA binding domain RNase_H PF00075.22 T031712_2 - 8.3e-12 45.4 0.1 1.2e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 RNase H RVT_thumb PF06817.12 T031712_3 - 3.4e-20 71.4 0.0 7.1e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain PHF12_MRG_bd PF16737.3 T230804_3 - 0.069 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain DUF1725 PF08333.9 T359956_1 - 1.1e-05 24.8 0.1 2.2e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) YlbE PF14003.4 T359956_1 - 9.4 6.6 8.6 5.4 7.4 0.0 3.5 4 0 0 4 4 4 0 YlbE-like protein Bradykinin PF06753.10 T383639_1 - 0.23 11.1 1.9 0.59 9.8 1.9 1.7 1 0 0 1 1 1 0 Bradykinin Cas_csx3 PF09620.8 T165220_2 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) RVT_1 PF00078.25 T348117_1 - 0.001 18.5 0.1 0.0016 17.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Thyroglob_assoc PF16597.3 T348117_1 - 0.026 14.7 0.1 0.06 13.5 0.1 1.6 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain Ribosomal_L39 PF00832.18 T304205_2 - 0.22 11.1 5.1 0.98 9.0 0.1 2.3 2 0 0 2 2 2 0 Ribosomal L39 protein DUF1725 PF08333.9 T269613_1 - 0.037 13.6 1.2 0.09 12.3 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T011527_2 - 0.013 15.0 0.2 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T172914_2 - 7.2e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DNA_pack_C PF02499.13 T383257_1 - 0.47 9.2 2.3 32 3.2 0.0 4.1 6 0 0 6 6 6 0 Probable DNA packing protein, C-terminus FLILHELTA PF10306.7 T094890_1 - 0.42 10.9 2.4 0.99 9.7 2.4 1.5 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA DUF2644 PF10841.6 T319631_2 - 0.034 14.2 0.3 0.048 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) Phage_min_cap2 PF06152.9 T038756_3 - 0.35 9.6 0.9 0.47 9.2 0.9 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF1725 PF08333.9 T038146_1 - 3.3e-06 26.4 0.6 7.1e-06 25.4 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Toxin_18 PF08087.9 T123669_1 - 0.43 10.5 6.3 0.048 13.5 0.5 2.5 2 0 0 2 2 2 0 Conotoxin O-superfamily TLV_coat PF00429.17 T171582_1 - 1e-17 63.9 1.6 1.6e-17 63.3 1.6 1.2 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) RVT_1 PF00078.25 T171582_1 - 6.6e-08 32.2 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gag_p30 PF02093.14 T171582_2 - 8e-52 175.7 0.0 1.4e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_MA PF01140.17 T171582_2 - 9.4e-17 60.8 4.7 1.6e-16 60.0 4.7 1.4 1 0 0 1 1 1 1 Matrix protein (MA), p15 RNase_H PF00075.22 T171582_2 - 6e-15 55.6 1.0 8.4e-15 55.1 0.3 1.6 2 0 0 2 2 2 1 RNase H RVP PF00077.18 T171582_2 - 2.1e-05 24.6 0.0 3.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.4 T171582_2 - 0.072 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease TLV_coat PF00429.17 T171582_3 - 1.3e-36 126.3 12.0 1.6e-35 122.7 12.0 2.0 1 1 0 1 1 1 1 ENV polyprotein (coat polyprotein) HnRNP_M PF11532.6 T281020_2 - 3.9 7.6 5.1 7.6 6.7 5.1 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M DUF4596 PF15363.4 T030390_1 - 0.34 11.0 1.9 18 5.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) RGS12_us1 PF16613.3 T064878_3 - 0.12 12.6 1.1 0.17 12.1 1.1 1.3 1 0 0 1 1 1 0 Unstructured region of RGS12 RRXRR PF14239.4 T108620_2 - 1 9.0 9.7 1.8 8.3 9.7 1.2 1 0 0 1 1 1 0 RRXRR protein FAD_binding_4 PF01565.21 T098317_2 - 0.096 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain DUF1725 PF08333.9 T256839_2 - 1.5e-07 30.7 1.0 2.6e-07 30.0 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) BING4CT PF08149.9 T356516_1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 BING4CT (NUC141) domain TMEM192 PF14802.4 T356516_2 - 1.2 8.0 7.7 1.9 7.4 7.7 1.2 1 0 0 1 1 1 0 TMEM192 family DUF1725 PF08333.9 T264245_2 - 7.2e-07 28.6 0.7 1.5e-06 27.5 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T026059_2 - 0.00025 20.5 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 T026059_3 - 3.4e-08 33.1 0.0 5.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4417 PF14386.4 T026059_3 - 0.0024 17.3 0.1 0.004 16.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4417) GSAP-16 PF14959.4 T011261_3 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term DUF1725 PF08333.9 T143988_2 - 0.0027 17.2 0.1 0.0063 16.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Mit_proteolip PF08039.9 T091387_3 - 9.3 6.5 9.6 0.094 12.9 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial proteolipid zf-Tim10_DDP PF02953.13 T292124_3 - 0.15 11.6 3.1 0.11 12.0 0.7 1.9 2 0 0 2 2 2 0 Tim10/DDP family zinc finger DUF1725 PF08333.9 T212416_1 - 0.0028 17.1 0.2 0.0061 16.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Apelin PF15360.4 T011405_3 - 0.17 12.3 3.1 0.5 10.8 3.1 1.8 1 0 0 1 1 1 0 APJ endogenous ligand ADH_N PF08240.10 T348643_3 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RVT_1 PF00078.25 T117603_2 - 3e-10 39.9 0.0 4.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4801 PF16059.3 T257760_3 - 1.2 9.0 4.3 5.3 7.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4801) Pentapeptide_4 PF13599.4 T040371_1 - 2.3e-16 59.5 4.9 0.24 11.4 0.2 8.7 4 2 5 9 9 9 7 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.4 T040371_2 - 8.8e-13 48.1 3.4 0.38 10.8 0.0 7.1 7 0 0 7 7 7 5 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.4 T040371_3 - 1.5e-08 34.5 13.1 0.0032 17.4 0.0 6.8 3 3 2 5 5 5 4 Pentapeptide repeats (9 copies) OrfB_IS605 PF01385.17 T304855_3 - 0.11 12.7 2.9 0.23 11.6 2.9 1.5 1 0 0 1 1 1 0 Probable transposase Toxin_18 PF08087.9 T343810_3 - 0.037 13.9 1.7 0.13 12.2 1.7 1.9 1 0 0 1 1 1 0 Conotoxin O-superfamily CENP-B_N PF04218.11 T285938_2 - 0.028 13.9 0.4 0.075 12.5 0.4 1.8 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF1725 PF08333.9 T270997_3 - 2.1e-08 33.4 1.3 4.5e-08 32.4 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T377978_1 - 4.9e-40 137.4 4.6 8.3e-40 136.6 4.6 1.3 1 0 0 1 1 1 1 L1 transposable element RVT_1 PF00078.25 T377978_2 - 1.9e-15 56.8 3.7 2.3e-11 43.5 2.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T377978_2 - 5.3e-08 32.2 1.3 1.4e-07 30.8 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Exo_endo_phos PF03372.21 T377978_2 - 0.0013 18.8 0.1 0.0023 18.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.25 T377978_3 - 1.1e-07 31.5 0.4 4.4e-07 29.5 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Somatomedin_B PF01033.15 T366557_3 - 0.049 13.9 3.9 0.094 13.0 3.9 1.4 1 0 0 1 1 1 0 Somatomedin B domain WGR PF05406.13 T363754_2 - 0.18 11.8 0.2 0.28 11.1 0.2 1.2 1 0 0 1 1 1 0 WGR domain DUF3915 PF13054.4 T321581_3 - 1.2 9.0 16.2 0.34 10.8 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Transposase_22 PF02994.12 T362826_2 - 4.9e-19 68.3 1.5 9.3e-13 47.6 0.1 2.1 2 0 0 2 2 2 2 L1 transposable element Transposase_22 PF02994.12 T362826_3 - 1.4e-08 33.8 0.2 1.4e-08 33.8 0.2 1.5 2 0 0 2 2 2 1 L1 transposable element RVT_1 PF00078.25 T159454_2 - 1.5e-08 34.3 0.1 2.5e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 T159454_3 - 8.4e-07 28.6 2.1 1.5e-06 27.8 2.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T056451_2 - 0.08 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T381471_3 - 6e-09 35.2 1.8 9.7e-09 34.5 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T197531_3 - 2.7e-07 29.9 0.3 6e-07 28.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T372818_2 - 0.0046 16.5 0.2 0.0088 15.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T019699_3 - 0.00024 20.6 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc5 PF03221.14 T200846_1 - 1.7e-05 24.6 0.1 4.3e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.11 T200846_1 - 0.12 11.9 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain CENP-B_N PF04218.11 T200846_2 - 0.0079 15.7 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DDE_1 PF03184.17 T200846_2 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_1 PF03184.17 T200846_3 - 1.2e-07 31.4 0.1 2.1e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SHIPPO-rpt PF07004.10 T316538_3 - 1 10.3 4.8 33 5.5 0.4 3.0 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat DUF1725 PF08333.9 T122545_1 - 8.5e-07 28.3 0.9 1.8e-06 27.3 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DDE_1 PF03184.17 T185263_1 - 7.4e-29 100.4 0.7 1.2e-28 99.8 0.7 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.14 T185263_1 - 0.0034 17.3 0.1 0.0067 16.3 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.11 T185263_3 - 0.0052 16.3 0.2 0.011 15.2 0.2 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DUF1725 PF08333.9 T012145_1 - 0.00021 20.7 0.5 0.00051 19.5 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T019557_1 - 6e-05 22.4 0.5 0.00014 21.3 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF3665 PF12427.6 T072031_1 - 0.88 9.2 3.4 0.41 10.2 0.9 1.8 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Peptidase_S13 PF02113.13 T227057_2 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Mit_proteolip PF08039.9 T224155_2 - 0.22 11.8 12.5 0.52 10.5 12.5 1.6 1 0 0 1 1 1 0 Mitochondrial proteolipid FAM27 PF15832.3 T224155_3 - 0.45 10.9 2.6 1.1 9.7 2.6 1.6 1 0 0 1 1 1 0 FAM27 D and E protein family DUF1725 PF08333.9 T356046_2 - 4.6e-07 29.2 1.2 1.3e-06 27.7 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) Glucokinase PF02685.14 T108860_3 - 0.021 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Glucokinase DUF1932 PF09130.9 T306724_2 - 0.24 11.3 0.0 28 4.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) 2-oxoacid_dh PF00198.21 T001098_1 - 0.1 11.9 0.3 11 5.2 0.0 3.0 4 0 0 4 4 4 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) MVL PF12151.6 T001098_1 - 0.15 11.8 50.6 3.8 7.3 0.2 8.6 8 0 0 8 8 8 0 Mannan-binding protein Trp_leader1 PF08055.9 T338083_2 - 2.1 8.0 7.3 5.3 6.7 7.3 1.6 1 0 0 1 1 1 0 Tryptophan leader peptide CTD PF12815.5 T053414_2 - 0.27 11.7 4.1 0.55 10.7 1.0 2.4 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 LYRIC PF15686.3 T187626_2 - 0.12 11.8 2.0 6.3 6.1 0.0 2.0 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family HTH_Tnp_Tc5 PF03221.14 T041872_1 - 0.00091 19.1 0.2 0.0017 18.2 0.2 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.17 T041872_2 - 1.1e-05 25.0 0.1 1.8e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.17 T041872_3 - 3e-05 23.5 0.2 4.8e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sec16_C PF12931.5 T274073_3 - 0.017 14.7 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 RVT_1 PF00078.25 T274469_2 - 9.9e-14 51.2 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3309 PF11752.6 T321473_3 - 0.045 13.7 1.0 0.099 12.6 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) CX9C PF16860.3 T059184_1 - 0.18 11.7 1.7 2 8.4 0.2 2.5 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Rz1 PF06085.9 T059184_2 - 0.067 12.8 0.3 0.067 12.8 0.3 2.0 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor DUF1725 PF08333.9 T057530_3 - 0.00025 20.5 0.6 0.00051 19.5 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Cys_rich_CWC PF14375.4 T236830_1 - 0.0024 18.1 1.0 1.4 9.3 0.1 2.6 2 0 0 2 2 2 2 Cysteine-rich CWC DUF1725 PF08333.9 T100542_2 - 5.2e-08 32.2 0.7 5.2e-08 32.2 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) FAM27 PF15832.3 T286831_1 - 0.0004 20.7 2.9 0.0004 20.7 2.9 3.2 2 1 0 2 2 2 1 FAM27 D and E protein family MIP-T3 PF10243.7 T286831_1 - 0.07 11.7 16.5 0.12 11.0 16.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAM27 PF15832.3 T286831_3 - 0.0021 18.4 2.7 0.0021 18.4 2.7 3.2 2 1 0 2 2 2 1 FAM27 D and E protein family DUF4564 PF15169.4 T048630_3 - 4.2 6.9 6.8 3 7.4 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) DUF3704 PF12488.6 T265163_2 - 1.5 8.4 6.4 0.26 10.8 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Transposase_22 PF02994.12 T328619_2 - 7e-30 104.0 7.8 6.3e-29 100.8 0.4 2.2 2 0 0 2 2 2 2 L1 transposable element RVT_1 PF00078.25 T328619_2 - 5e-15 55.5 0.4 1e-14 54.4 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T328619_2 - 2.2e-05 23.9 0.6 4.4e-05 22.9 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Ferlin_C PF16165.3 T307169_3 - 5.9 6.7 5.3 8.7 6.1 5.3 1.2 1 0 0 1 1 1 0 Ferlin C-terminus DUF4753 PF15945.3 T066851_1 - 0.082 12.6 1.4 0.23 11.2 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4753) LisH_2 PF16045.3 T082470_1 - 0.14 11.1 4.1 3.5 6.6 0.5 2.6 2 0 0 2 2 2 0 LisH CAAX_1 PF15895.3 T355146_2 - 0.0029 17.3 0.9 0.0041 16.8 0.9 1.3 1 0 0 1 1 1 1 CAAX box cerebral protein 1 Cupredoxin_1 PF13473.4 T095815_1 - 0.17 11.9 0.0 0.2 11.6 0.0 1.3 1 1 0 1 1 1 0 Cupredoxin-like domain Zn_clus PF00172.16 T038104_1 - 0.58 10.2 3.0 3.8 7.6 0.2 2.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Collagen_mid PF15984.3 T121476_1 - 0.0093 15.6 4.4 0.015 14.9 4.4 1.2 1 0 0 1 1 1 1 Bacterial collagen, middle region CbiK PF06180.9 T101482_1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) zf-UDP PF14569.4 T037715_2 - 0.043 13.8 0.1 0.091 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Humanin PF15040.4 T089017_1 - 0.36 10.3 2.1 0.72 9.3 2.1 1.5 1 0 0 1 1 1 0 Humanin family SR-25 PF10500.7 T213119_1 - 0.039 13.4 10.9 0.054 13.0 10.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AP3D1 PF06375.9 T213119_1 - 0.26 11.4 9.7 0.45 10.7 9.7 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.8 T213119_1 - 5.5 6.9 9.1 8.1 6.4 9.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1725 PF08333.9 T187555_3 - 1.2e-05 24.7 2.0 0.12 11.9 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T340537_2 - 1.2e-08 34.2 0.8 2.5e-08 33.2 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Mit_proteolip PF08039.9 T157404_1 - 5.7 7.2 19.4 1.3 9.3 5.1 2.4 1 1 1 2 2 2 0 Mitochondrial proteolipid Fe_hyd_lg_C PF02906.12 T157404_3 - 0.11 12.0 0.2 0.31 10.5 0.2 1.6 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain DUF1725 PF08333.9 T153408_1 - 1.1e-07 31.2 0.4 2.4e-07 30.1 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF5133 PF17196.2 T052697_1 - 0.29 11.2 10.1 61 3.8 0.1 5.1 3 1 1 4 4 4 0 Protein of unknown function (DUF5133) DUF1725 PF08333.9 T227229_2 - 1.9e-07 30.4 5.1 0.0019 17.7 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1725) RhlB PF12300.6 T231658_1 - 0.55 10.3 5.4 0.82 9.7 5.4 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB PPTA PF01239.20 T224681_1 - 8.6 6.1 6.4 7.8 6.3 0.4 2.9 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat dUTPase PF00692.17 T224681_2 - 1.8e-10 40.4 0.0 3.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 dUTPase rve PF00665.24 T224681_2 - 1.3e-08 34.9 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.22 T224681_3 - 0.0031 17.6 0.2 0.0054 16.8 0.2 1.2 1 0 0 1 1 1 1 RNase H DUF4575 PF15143.4 T359690_1 - 9.4e-26 90.4 40.8 2.8e-11 43.6 11.9 4.7 2 2 2 4 4 4 4 Domain of unknown function (DUF4575) DUF4575 PF15143.4 T359690_2 - 1.1e-35 122.5 23.1 2.9e-26 92.1 10.6 3.7 2 1 1 3 3 3 3 Domain of unknown function (DUF4575) DUF4575 PF15143.4 T359690_3 - 2.8e-31 108.3 39.2 7.7e-22 77.8 6.9 4.8 4 1 1 5 5 5 4 Domain of unknown function (DUF4575) Gelsolin PF00626.20 T211436_3 - 0.065 13.0 0.1 22 4.9 0.0 3.2 3 0 0 3 3 3 0 Gelsolin repeat DUF1725 PF08333.9 T325729_2 - 0.06 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T308711_1 - 9.7e-07 28.4 0.1 1.9e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T308711_1 - 0.0054 16.2 0.6 0.015 14.8 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Exo_endo_phos PF03372.21 T308711_3 - 2.2e-05 24.5 0.2 6.4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.25 T283208_2 - 1e-31 110.1 0.6 2.4e-31 108.9 0.6 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_22 PF02994.12 T283208_2 - 1.1e-18 67.1 11.4 1.4e-07 30.6 2.0 3.2 3 0 0 3 3 3 3 L1 transposable element DUF1725 PF08333.9 T283208_2 - 2.5e-07 30.0 1.1 5.7e-07 28.9 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T283208_3 - 1e-54 185.7 2.6 1.7e-54 184.9 2.6 1.3 1 0 0 1 1 1 1 L1 transposable element FA PF08736.9 T171715_2 - 0.25 11.4 1.5 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 FERM adjacent (FA) Gag_p30 PF02093.14 T171715_3 - 6.8e-09 35.4 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Gag P30 core shell protein DUF1725 PF08333.9 T296988_2 - 4.1e-07 29.3 1.1 1.1e-06 27.9 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) Orthopox_B11R PF07033.9 T296988_2 - 0.16 11.7 2.2 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 Orthopoxvirus B11R protein DUF1725 PF08333.9 T357405_2 - 5.4e-07 29.0 1.3 5.4e-07 29.0 1.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T274701_3 - 0.014 14.9 0.6 0.032 13.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Imm31 PF15591.4 T219385_3 - 0.46 10.2 3.1 1.8 8.3 0.2 2.7 2 1 0 2 2 2 0 Immunity protein 31 Toxin_9 PF02819.13 T057953_1 - 4.7 7.4 7.2 5.4 7.2 3.5 2.5 2 0 0 2 2 2 0 Spider toxin DEC1 PF15859.3 T315443_2 - 0.028 14.4 0.1 0.07 13.1 0.1 1.7 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family zf-RRN7 PF11781.6 T044438_1 - 4.7 6.9 6.4 4.1 7.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF2101 PF09874.7 T350856_1 - 0.42 10.1 9.2 0.69 9.4 9.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) DUF1725 PF08333.9 T031219_3 - 0.0023 17.4 0.1 0.005 16.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T209376_1 - 1.2e-17 63.7 0.0 1.8e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 L1 transposable element DUF1725 PF08333.9 T209376_1 - 1.8e-07 30.5 0.4 4.6e-07 29.2 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T209376_2 - 3.2e-54 184.0 4.0 5.8e-54 183.2 4.0 1.4 1 0 0 1 1 1 1 L1 transposable element RVT_1 PF00078.25 T209376_2 - 6.9e-19 68.1 0.0 1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 T209376_3 - 1.6e-13 50.6 0.3 2.6e-13 49.9 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T016239_3 - 7.9e-05 22.1 0.1 0.0002 20.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T262006_1 - 9.8e-08 31.3 1.1 2.3e-07 30.1 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1681 PF07933.12 T085098_1 - 0.093 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) HMG_box_2 PF09011.8 T081697_1 - 0.058 13.9 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain ARID PF01388.19 T264618_2 - 0.13 12.8 0.3 0.32 11.6 0.0 1.7 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain Transposase_22 PF02994.12 T305840_1 - 4e-52 177.2 4.8 7.2e-52 176.3 4.8 1.3 1 0 0 1 1 1 1 L1 transposable element TLV_coat PF00429.17 T305840_1 - 1.3e-16 60.3 1.6 2e-16 59.6 1.6 1.2 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) RVT_1 PF00078.25 T305840_1 - 0.0058 16.0 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_22 PF02994.12 T305840_2 - 4.5e-29 101.3 13.6 2.1e-26 92.6 13.6 2.3 1 1 0 1 1 1 1 L1 transposable element RVT_1 PF00078.25 T305840_2 - 2.1e-14 53.5 0.2 1.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TLV_coat PF00429.17 T305840_2 - 1.9e-10 39.9 6.6 6.8e-06 24.9 0.8 2.2 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) Transposase_22 PF02994.12 T305840_3 - 5.2e-25 87.9 0.2 7.9e-25 87.3 0.2 1.2 1 0 0 1 1 1 1 L1 transposable element Transposase_22 PF02994.12 T343062_2 - 1.4e-10 40.5 0.2 2e-10 39.9 0.2 1.1 1 0 0 1 1 1 1 L1 transposable element Exo_endo_phos PF03372.21 T282732_1 - 0.0082 16.3 0.0 0.02 15.0 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF1610 PF07754.9 T182457_2 - 0.035 14.0 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DUF3778 PF12620.6 T182457_3 - 0.062 12.7 0.4 12 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3778) FAM27 PF15832.3 T271375_3 - 9.4e-19 67.6 19.2 9.4e-19 67.6 19.2 4.0 4 0 0 4 4 4 1 FAM27 D and E protein family DUF3704 PF12488.6 T037229_2 - 0.026 14.0 1.5 0.059 12.9 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Rhodanese PF00581.18 T308579_1 - 0.00082 19.7 0.1 0.0013 19.0 0.1 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Oxidored-like PF09791.7 T364886_3 - 0.91 9.1 5.8 0.44 10.1 0.1 2.4 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal DUF1725 PF08333.9 T081633_3 - 2.3e-08 33.3 0.4 4.4e-08 32.4 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) FAM27 PF15832.3 T192294_2 - 0.088 13.2 20.3 0.17 12.3 20.3 1.4 1 0 0 1 1 1 0 FAM27 D and E protein family Eapp_C PF10238.7 T310094_1 - 0.039 13.9 3.2 0.062 13.3 3.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein FAM176 PF14851.4 T310094_1 - 0.29 10.7 2.9 0.47 10.0 2.9 1.3 1 0 0 1 1 1 0 FAM176 family DUF2828 PF11443.6 T310094_1 - 0.35 8.8 5.4 0.47 8.4 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2956 PF11169.6 T310094_1 - 2.1 8.5 12.2 4 7.6 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) NARP1 PF12569.6 T310094_1 - 6.9 5.3 17.0 9.5 4.8 17.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.12 T310094_1 - 9.3 4.3 9.7 13 3.8 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.17 T310094_2 - 0.034 13.8 1.1 0.056 13.1 1.1 1.3 1 0 0 1 1 1 0 Connexin DUF4597 PF15366.4 T224722_3 - 0.029 14.0 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Ten_N PF06484.10 T139361_3 - 0.057 13.2 1.9 0.074 12.8 1.9 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region Toxin_18 PF08087.9 T373172_1 - 0.0023 17.8 0.5 0.0066 16.3 0.5 1.8 1 0 0 1 1 1 1 Conotoxin O-superfamily RVT_1 PF00078.25 T360453_2 - 4.9e-14 52.2 1.2 8.1e-14 51.5 1.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T253916_1 - 0.00068 19.1 1.3 0.0015 18.0 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) RR_TM4-6 PF06459.10 T253916_1 - 5.6 6.6 20.4 8.1 6.0 20.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.12 T253916_3 - 0.13 12.5 8.4 0.31 11.3 8.4 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Transposase_22 PF02994.12 T235712_2 - 1.1e-05 24.3 0.0 1.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 L1 transposable element Yae1_N PF09811.7 T038153_1 - 0.0048 16.5 6.4 0.0077 15.8 6.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RR_TM4-6 PF06459.10 T038153_1 - 4.4 6.9 18.1 9.3 5.8 18.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MIP-T3 PF10243.7 T038153_2 - 0.00041 19.1 23.9 0.00062 18.5 23.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Yae1_N PF09811.7 T038153_2 - 0.14 11.8 4.3 0.25 10.9 4.3 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal NPR3 PF03666.11 T038153_2 - 1.8 7.1 17.5 2.7 6.5 17.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.12 T038153_2 - 8.4 4.4 20.1 12 4.0 20.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1725 PF08333.9 T293321_2 - 5.4e-07 28.9 0.5 1e-06 28.1 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_1 PF01359.16 T089812_1 - 1.3e-07 31.3 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) HEAT PF02985.20 T097308_1 - 0.00014 21.6 0.1 0.38 11.0 0.1 2.3 2 0 0 2 2 2 2 HEAT repeat zf-PHD-like PF15446.4 T292269_3 - 0.0094 15.5 0.8 0.012 15.1 0.8 1.1 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Cir_N PF10197.7 T304161_3 - 0.16 12.1 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Transposase_22 PF02994.12 T117780_2 - 1.7e-13 50.1 0.0 2.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 L1 transposable element FXa_inhibition PF14670.4 T001012_2 - 0.055 13.6 1.9 0.055 13.6 1.9 3.4 2 2 2 4 4 4 0 Coagulation Factor Xa inhibitory site DUF4338 PF14236.4 T209559_3 - 0.071 12.2 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) KIAA1430 PF13879.4 T099979_2 - 0.098 13.3 0.2 0.18 12.5 0.2 1.4 1 0 0 1 1 1 0 KIAA1430 homologue HIF-1a_CTAD PF08778.8 T223017_1 - 0.005 16.3 0.6 64 3.2 0.0 5.5 6 0 0 6 6 6 2 HIF-1 alpha C terminal transactivation domain YesK PF14150.4 T048688_2 - 0.074 13.1 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 YesK-like protein mRNA_decap_C PF16741.3 T103504_1 - 0.0033 16.5 0.0 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus Ribosomal_L18_c PF14204.4 T051648_1 - 6.9e-05 23.5 4.2 0.0001 22.9 4.2 1.3 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region TAF8_C PF10406.7 T340903_2 - 3.4 8.2 6.9 17 5.9 6.9 2.0 1 1 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term APH_6_hur PF04655.12 T259847_3 - 0.092 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase DUF1725 PF08333.9 T323449_2 - 3.1e-05 23.4 0.2 8.3e-05 22.0 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF4604 PF15377.4 T032974_3 - 1.8 8.8 8.3 2.7 8.3 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CENP-B_N PF04218.11 T030281_1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DUF1725 PF08333.9 T214286_2 - 0.008 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Arabino_trans_C PF14896.4 T260425_3 - 0.065 12.1 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain DUF4618 PF15397.4 T260425_3 - 2 7.6 5.0 11 5.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) MbeD_MobD PF04899.10 T260425_3 - 2.4 8.2 19.9 0.64 10.0 6.2 2.9 2 1 0 2 2 2 0 MbeD/MobD like DUF1492 PF07374.9 T122843_3 - 0.14 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Toxin_18 PF08087.9 T088460_3 - 3.6 7.5 9.9 0.88 9.5 2.1 2.8 2 0 0 2 2 2 0 Conotoxin O-superfamily FAM27 PF15832.3 T092811_1 - 0.2 12.1 15.5 0.38 11.2 15.5 1.3 1 0 0 1 1 1 0 FAM27 D and E protein family FAM27 PF15832.3 T092811_2 - 0.0013 19.1 9.1 0.0024 18.3 9.1 1.3 1 0 0 1 1 1 1 FAM27 D and E protein family FAM27 PF15832.3 T092811_3 - 0.0058 17.0 9.4 0.011 16.1 9.4 1.4 1 0 0 1 1 1 1 FAM27 D and E protein family FAM27 PF15832.3 T358861_2 - 5.2e-09 36.4 12.5 5.2e-09 36.4 12.5 2.6 2 1 1 3 3 3 1 FAM27 D and E protein family DUF1725 PF08333.9 T297918_1 - 0.014 14.9 0.5 0.014 14.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Transposase_1 PF01359.16 T093890_3 - 2.3e-24 84.9 0.2 5.1e-24 83.8 0.2 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DUF1725 PF08333.9 T267208_2 - 5.3e-06 25.8 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Clat_adaptor_s PF01217.18 T190568_1 - 0.0075 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PBP1_TM PF14812.4 T160223_3 - 0.095 13.0 4.9 0.17 12.2 4.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.4 T160223_3 - 0.11 12.0 4.4 0.2 11.2 4.4 1.3 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.12 T160223_3 - 0.6 9.7 3.8 0.99 9.0 3.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Mit_proteolip PF08039.9 T213812_3 - 0.086 13.0 3.6 0.18 12.0 3.6 1.5 1 0 0 1 1 1 0 Mitochondrial proteolipid Gag_p30 PF02093.14 T273332_1 - 0.052 12.9 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein zf-CCHC PF00098.21 T273332_3 - 0.16 12.0 6.6 0.027 14.4 1.7 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF1725 PF08333.9 T283532_3 - 1.7e-08 33.8 1.6 5.1e-08 32.2 1.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) BAGE PF08180.9 T144189_3 - 0.036 14.0 1.0 0.08 12.9 1.0 1.5 1 0 0 1 1 1 0 B melanoma antigen family Phage_Coat_Gp8 PF05371.10 T342024_2 - 7.5 6.3 12.2 32 4.2 0.5 3.3 3 0 0 3 3 3 0 Phage major coat protein, Gp8 Collagen PF01391.16 T212062_2 - 0.065 12.9 16.3 0.2 11.3 16.3 1.8 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) HTH_24 PF13412.4 T245881_1 - 0.034 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Transposase_1 PF01359.16 T245881_2 - 1.3e-17 63.2 0.1 2.1e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) Transposase_1 PF01359.16 T245881_3 - 5.2e-10 38.9 0.2 1.2e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) Atrophin-1 PF03154.13 T081190_1 - 4.8 5.2 6.0 6.7 4.7 6.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 T081190_2 - 4.7 7.1 5.2 8.8 6.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 T081190_3 - 1.6 6.8 8.3 2.2 6.3 8.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1725 PF08333.9 T293474_3 - 1.2e-06 27.9 0.6 2.9e-06 26.6 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) HTH_Tnp_Tc5 PF03221.14 T025114_2 - 0.018 15.0 1.3 0.022 14.6 0.3 1.8 2 1 0 2 2 2 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.17 T025114_2 - 0.047 13.1 0.0 0.14 11.6 0.0 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease 3Beta_HSD PF01073.17 T219965_1 - 0.22 10.4 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Phage_Coat_Gp8 PF05371.10 T342014_2 - 2.5 7.8 12.2 22 4.8 0.5 3.3 3 0 0 3 3 3 0 Phage major coat protein, Gp8 Atrophin-1 PF03154.13 T315080_1 - 0.2 9.7 0.8 0.28 9.3 0.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family RR_TM4-6 PF06459.10 T197497_1 - 5.3 6.6 12.5 8 6.1 12.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt_Eps PF04627.11 T197497_3 - 0.22 11.4 1.7 0.71 9.8 1.7 1.9 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain FAM75 PF14650.4 T363574_3 - 2.9e-07 30.3 8.7 6e-07 29.2 8.7 1.5 1 0 0 1 1 1 1 FAM75 family RVT_1 PF00078.25 T331964_1 - 0.0001 21.8 1.0 0.00014 21.3 1.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T355061_3 - 1.8e-07 30.5 0.1 4.1e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF3678 PF12435.6 T296570_2 - 0.11 11.6 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) RVT_1 PF00078.25 T343610_1 - 1.4e-06 27.9 1.6 3.3e-06 26.7 1.6 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3430 PF11912.6 T092155_2 - 0.17 11.8 3.3 0.33 10.8 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) DDE_1 PF03184.17 T252652_3 - 5.5e-07 29.2 0.0 9.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.11 T252652_3 - 0.0021 17.5 0.2 0.0043 16.5 0.2 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Bradykinin PF06753.10 T252652_3 - 0.017 14.7 2.2 0.039 13.5 2.2 1.6 1 0 0 1 1 1 0 Bradykinin Fer4 PF00037.25 T195716_3 - 0.13 12.0 3.1 0.2 11.4 0.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DUF2500 PF10694.7 T139200_1 - 1.7 9.1 5.1 8.8 6.8 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2500) RVT_1 PF00078.25 T025242_1 - 1.3e-06 28.0 0.0 2.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Connexin PF00029.17 T025242_3 - 1.8 8.1 5.3 2.6 7.6 5.3 1.3 1 0 0 1 1 1 0 Connexin DUF1725 PF08333.9 T187560_1 - 0.033 13.7 1.3 0.043 13.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) CBM_21 PF03370.11 T342862_3 - 0.021 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) DUF3704 PF12488.6 T131870_1 - 0.0012 18.3 0.6 0.0022 17.5 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3704) CENP-B_N PF04218.11 T030280_1 - 0.00016 21.1 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DUF1725 PF08333.9 T061374_3 - 4.6e-07 29.2 1.7 9.3e-07 28.2 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF4705 PF15788.3 T323233_2 - 1.7e-05 24.8 22.4 0.00027 20.9 6.4 8.0 6 2 2 8 8 8 2 Domain of unknown function (DUF4705) DUF4705 PF15788.3 T323233_3 - 0.0017 18.4 35.9 0.019 15.0 15.4 5.4 3 1 1 4 4 4 3 Domain of unknown function (DUF4705) KdpA PF03814.13 T018005_1 - 0.1 10.6 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit Transposase_22 PF02994.12 T298155_2 - 0.052 12.3 0.0 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 L1 transposable element NinF PF05810.10 T350880_2 - 0.12 12.1 1.0 0.84 9.4 0.0 2.2 2 0 0 2 2 2 0 NinF protein AP3D1 PF06375.9 T166142_1 - 3.9 7.6 6.8 6.3 6.9 6.8 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4710 PF15828.3 T166142_2 - 0.012 15.5 2.4 0.022 14.7 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) SNARE PF05739.17 T004478_3 - 7.1 6.6 5.5 2.3 8.2 0.6 2.0 2 0 0 2 2 2 0 SNARE domain TLV_coat PF00429.17 T367553_1 - 6.1e-23 81.2 0.2 8.1e-23 80.8 0.2 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) DUF3704 PF12488.6 T373772_1 - 0.0028 17.1 0.4 0.0061 16.1 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3704) Transposase_22 PF02994.12 T373772_2 - 7.3e-08 31.5 0.0 1e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 L1 transposable element Ribosomal_L41 PF05162.11 T255311_2 - 7.2e-06 25.8 25.5 0.00011 22.0 25.5 2.6 1 1 0 1 1 1 1 Ribosomal protein L41 Collagen PF01391.16 T212049_1 - 0.078 12.6 16.3 0.2 11.3 16.3 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Gag_p30 PF02093.14 T383883_3 - 0.0015 17.9 0.1 0.0059 16.0 0.0 1.8 2 0 0 2 2 2 1 Gag P30 core shell protein Bradykinin PF06753.10 T261948_2 - 0.041 13.5 0.7 0.14 11.7 0.7 2.0 1 0 0 1 1 1 0 Bradykinin DUF1725 PF08333.9 T067812_3 - 0.071 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Bradykinin PF06753.10 T055177_3 - 0.08 12.5 2.6 0.33 10.6 2.6 2.1 1 0 0 1 1 1 0 Bradykinin zf-RanBP PF00641.16 T030768_2 - 8.9 5.6 14.0 50 3.2 14.0 2.3 1 1 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF1725 PF08333.9 T298655_2 - 2.4e-05 23.7 1.2 5.3e-05 22.6 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T042786_3 - 0.0038 16.7 0.5 0.0084 15.6 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF3704 PF12488.6 T102562_1 - 0.031 13.8 2.4 0.078 12.5 2.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Zip PF02535.20 T211106_1 - 0.03 13.4 0.2 0.051 12.6 0.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.13 T211106_1 - 0.19 10.5 0.1 0.27 10.0 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.10 T211106_1 - 2.2 7.9 20.0 3.8 7.1 20.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4366 PF14283.4 T211106_1 - 5.4 6.3 4.7 8.7 5.6 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) NPR3 PF03666.11 T211106_2 - 1 8.0 12.3 1.8 7.1 12.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3704 PF12488.6 T243660_3 - 0.0014 18.1 3.3 0.0037 16.7 3.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3704) DUF3915 PF13054.4 T216364_2 - 0.14 12.1 1.0 0.25 11.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Transposase_22 PF02994.12 T206703_3 - 0.00024 20.0 0.2 0.00029 19.7 0.2 1.0 1 0 0 1 1 1 1 L1 transposable element AP3D1 PF06375.9 T153991_3 - 1.7 8.7 12.0 0.41 10.8 4.3 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF1725 PF08333.9 T116293_3 - 1.6e-05 24.3 0.1 4e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T027047_3 - 4e-06 26.2 0.4 7.8e-06 25.3 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Yae1_N PF09811.7 T148900_1 - 0.17 11.5 2.3 0.32 10.6 2.3 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.7 T148900_2 - 1.1 8.9 4.9 1.9 8.1 4.9 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.7 T148900_3 - 1 9.0 3.5 2 8.1 3.5 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal SOCS PF12610.6 T317170_1 - 0.031 14.6 1.5 0.13 12.5 0.5 2.5 2 0 0 2 2 2 0 Suppressor of cytokine signalling HTH_Mga PF08280.9 T192520_1 - 0.034 14.0 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Vitelline_membr PF10542.7 T280597_1 - 0.18 11.6 2.7 7.4 6.4 0.8 2.7 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region Metallothi_Euk2 PF12809.5 T315926_3 - 0.21 11.7 2.9 0.44 10.7 2.9 1.4 1 0 0 1 1 1 0 Eukaryotic metallothionein DUF1725 PF08333.9 T131782_3 - 0.0058 16.1 0.3 0.012 15.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T087261_1 - 0.043 13.4 0.9 0.086 12.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) LEP503 PF15221.4 T207595_3 - 0.12 12.4 0.6 0.29 11.2 0.6 1.6 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 DUF1725 PF08333.9 T072315_1 - 0.00055 19.4 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Toxin_18 PF08087.9 T174319_2 - 0.015 15.2 0.2 0.061 13.2 0.2 2.1 1 0 0 1 1 1 0 Conotoxin O-superfamily rve PF00665.24 T174319_3 - 6.2e-20 71.5 0.0 1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.22 T174319_3 - 4.9e-12 46.1 0.0 8.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-H2C2 PF09337.8 T174319_3 - 0.00016 21.8 0.1 0.00033 20.7 0.1 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Phage_fiber PF03335.11 T277934_3 - 0.075 13.1 0.4 0.075 13.1 0.4 1.9 2 0 0 2 2 2 0 Phage tail fibre repeat DUF1653 PF07866.9 T035063_1 - 0.06 13.5 0.2 0.097 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) Presenilin PF01080.15 T006699_3 - 0.5 8.9 8.6 0.88 8.1 8.6 1.3 1 0 0 1 1 1 0 Presenilin DUF3807 PF12720.5 T006699_3 - 3.2 7.9 24.4 6.6 6.9 8.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) RVT_1 PF00078.25 T279852_1 - 7.7e-10 38.5 0.2 1.9e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T279852_3 - 3.8e-07 29.5 1.1 9.8e-07 28.1 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) AP3D1 PF06375.9 T320650_1 - 1.6 8.9 6.7 4.1 7.5 6.7 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Mit_proteolip PF08039.9 T343913_3 - 1.2 9.4 10.9 3.1 8.0 10.9 1.6 1 0 0 1 1 1 0 Mitochondrial proteolipid RVT_1 PF00078.25 T265049_1 - 0.0071 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BLOC1_2 PF10046.7 T342336_2 - 0.4 10.9 4.3 0.73 10.1 4.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.19 T342336_2 - 0.42 10.2 2.4 0.69 9.5 2.4 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Transposase_22 PF02994.12 T342336_3 - 9.3e-28 97.0 3.5 1.1e-17 63.9 1.7 2.1 2 0 0 2 2 2 2 L1 transposable element GMAP PF06540.9 T343846_3 - 0.14 12.1 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) SHR3_chaperone PF08229.9 T005567_2 - 0.088 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Toxin_18 PF08087.9 T005567_2 - 0.48 10.3 6.5 0.59 10.0 2.2 2.4 2 0 0 2 2 2 0 Conotoxin O-superfamily KNOX2 PF03791.11 T071886_3 - 0.11 12.0 0.1 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 KNOX2 domain Pentapeptide_2 PF01469.16 T051522_1 - 0.0052 16.5 6.3 0.52 10.1 1.1 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) DUF1725 PF08333.9 T266743_3 - 0.0017 17.8 1.1 0.0032 16.9 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T276084_3 - 1.8e-07 30.5 0.3 3.4e-07 29.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF3704 PF12488.6 T351607_3 - 0.0032 16.9 3.3 0.016 14.7 3.3 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3704) DUF1725 PF08333.9 T136789_2 - 0.034 13.7 1.4 0.11 12.1 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Gag_MA PF01140.17 T073280_1 - 9.2e-06 25.2 0.1 1.9e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Matrix protein (MA), p15 ATG27 PF09451.8 T278103_3 - 1.5 8.5 9.8 2.6 7.7 9.8 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 MCPVI PF02993.12 T008309_1 - 0.17 11.5 4.6 0.33 10.6 4.6 1.4 1 0 0 1 1 1 0 Minor capsid protein VI DicB PF05358.9 T220810_2 - 0.05 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 DicB protein DUF1725 PF08333.9 T292416_2 - 7.3e-08 31.7 0.9 1.7e-07 30.6 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF3704 PF12488.6 T306684_3 - 0.012 15.2 0.4 0.026 14.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Glyco_hydro_36 PF17167.2 T220052_1 - 0.17 10.4 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain RVT_1 PF00078.25 T254000_1 - 5.2e-12 45.6 1.3 5.2e-12 45.6 1.3 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Grp1_Fun34_YaaH PF01184.17 T033355_1 - 0.29 10.6 2.2 0.49 9.8 2.2 1.3 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family DUF1725 PF08333.9 T314388_3 - 1.8e-05 24.1 1.1 3e-05 23.4 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) PBC PF03792.11 T266626_1 - 0.07 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 PBC domain HTH_Mga PF08280.9 T192517_3 - 0.042 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF1725 PF08333.9 T012146_3 - 0.00021 20.7 0.5 0.0005 19.5 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) PGA2 PF07543.10 T231277_1 - 1 9.2 11.0 0.03 14.2 4.1 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF3381 PF11861.6 T231277_1 - 1.4 8.6 12.4 0.042 13.6 5.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) CPSF100_C PF13299.4 T231277_1 - 4.7 7.2 6.2 0.97 9.5 0.1 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Nop53 PF07767.9 T231277_1 - 6.8 5.9 19.0 0.16 11.2 12.2 1.6 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Thx PF17070.3 T368401_2 - 0.19 11.8 1.4 0.77 9.8 1.4 2.0 1 0 0 1 1 1 0 30S ribosomal protein Thx Usg PF06233.10 T349488_3 - 0.054 13.5 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Usg-like family Transposase_22 PF02994.12 T376871_1 - 2.1e-08 33.3 10.1 6.2e-08 31.8 2.5 2.1 2 0 0 2 2 2 2 L1 transposable element DUF1725 PF08333.9 T376871_1 - 0.0041 16.6 0.3 0.0041 16.6 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T326072_1 - 0.055 13.0 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) MAGI_u5 PF16666.3 T003605_1 - 0.18 11.9 0.0 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 Unstructured region on MAGI Mit_proteolip PF08039.9 T103117_3 - 0.48 10.7 3.4 0.91 9.8 3.4 1.4 1 0 0 1 1 1 0 Mitochondrial proteolipid DUF1725 PF08333.9 T035987_2 - 0.13 11.9 1.2 0.25 10.9 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T355063_1 - 1.9e-07 30.4 0.1 4.1e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T027524_1 - 4.3e-16 58.6 0.2 6.5e-16 58.0 0.2 1.2 1 0 0 1 1 1 1 L1 transposable element DUF4575 PF15143.4 T359692_1 - 2.2e-31 108.6 39.2 7e-22 77.9 6.9 4.7 4 1 1 5 5 5 4 Domain of unknown function (DUF4575) DUF4575 PF15143.4 T359692_2 - 7.1e-26 90.8 41.0 2.8e-11 43.6 12.0 4.6 2 2 2 4 4 4 4 Domain of unknown function (DUF4575) DUF4575 PF15143.4 T359692_3 - 1.1e-35 122.5 23.1 2.6e-26 92.2 10.6 3.5 2 1 1 3 3 3 3 Domain of unknown function (DUF4575) Quaking_NLS PF16551.3 T288098_3 - 0.31 10.6 3.3 0.53 9.9 3.3 1.3 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking DUF1910 PF08928.8 T229568_2 - 0.022 14.6 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) NUC205 PF08168.9 T229568_2 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 NUC205 domain PBP1_TM PF14812.4 T160222_3 - 0.1 12.9 4.9 0.18 12.1 4.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.4 T160222_3 - 0.13 11.8 4.4 0.21 11.1 4.4 1.3 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.12 T160222_3 - 0.67 9.5 3.8 1 8.9 3.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4362 PF14275.4 T358127_2 - 0.12 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) UvrB PF12344.6 T102697_1 - 0.11 12.2 0.7 0.2 11.4 0.7 1.3 1 0 0 1 1 1 0 Ultra-violet resistance protein B zf-RRN7 PF11781.6 T370366_1 - 0.079 12.5 0.8 1.3 8.6 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Med19 PF10278.7 T370366_3 - 2.8 7.7 5.7 4.5 7.0 5.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Mit_proteolip PF08039.9 T036715_3 - 3.4 7.9 10.3 7.9 6.7 10.3 1.6 1 0 0 1 1 1 0 Mitochondrial proteolipid zf-NF-X1 PF01422.15 T014302_3 - 0.024 14.6 2.6 0.024 14.6 2.6 2.4 2 0 0 2 2 2 0 NF-X1 type zinc finger FAM176 PF14851.4 T290457_2 - 1.8 8.1 4.4 3 7.4 4.4 1.2 1 0 0 1 1 1 0 FAM176 family DUF1725 PF08333.9 T347392_1 - 0.071 12.7 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) zf-CCHC PF00098.21 T160319_3 - 0.0028 17.5 1.7 0.0028 17.5 1.7 2.5 2 0 0 2 2 2 1 Zinc knuckle Gag_p30 PF02093.14 T160319_3 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein zf-CCHC_5 PF14787.4 T160319_3 - 0.44 10.2 12.1 0.6 9.7 1.7 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger GST_C PF00043.23 T031981_3 - 0.14 12.3 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3704 PF12488.6 T308712_1 - 1.6 8.3 5.8 3.8 7.1 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Extensin_1 PF02095.13 T197351_2 - 1.2 9.4 10.2 2.5 8.4 10.2 1.5 1 0 0 1 1 1 0 Extensin-like protein repeat DUF1851 PF08906.9 T071097_2 - 0.079 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1851) ERCC3_RAD25_C PF16203.3 T071097_3 - 0.0015 17.7 1.7 38 3.2 0.0 5.2 5 1 1 6 6 6 5 ERCC3/RAD25/XPB C-terminal helicase Gag_p30 PF02093.14 T298119_1 - 7.4e-15 54.9 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Gag P30 core shell protein rve PF00665.24 T298119_3 - 1.2e-06 28.6 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.22 T266066_1 - 0.065 13.3 0.6 0.092 12.8 0.6 1.2 1 0 0 1 1 1 0 RNase H DUF1725 PF08333.9 T226011_2 - 0.00014 21.3 0.4 0.00029 20.3 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) BAGE PF08180.9 T214907_3 - 2.9 7.9 4.8 6.1 6.9 4.8 1.4 1 0 0 1 1 1 0 B melanoma antigen family RVT_1 PF00078.25 T319218_1 - 7.1e-24 84.4 0.0 1.1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OGFr_III PF04680.11 T351970_1 - 0.61 10.6 2.9 1.8 9.1 2.9 1.8 1 0 0 1 1 1 0 Opioid growth factor receptor repeat ETRAMP PF09716.8 T205365_2 - 0.0038 17.1 1.9 0.05 13.5 0.0 2.8 3 0 0 3 3 3 2 Malarial early transcribed membrane protein (ETRAMP) Trypan_PARP PF05887.9 T153780_2 - 0.036 14.0 10.6 0.087 12.7 10.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Imm_superinfect PF14373.4 T373315_3 - 0.045 13.5 2.4 0.092 12.6 2.4 1.5 1 0 0 1 1 1 0 Superinfection immunity protein TAFII55_N PF04658.11 T071509_3 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 TAFII55 protein conserved region Pentapeptide_4 PF13599.4 T144212_1 - 2.1e-11 43.7 0.0 0.00075 19.4 0.0 4.0 3 2 1 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.4 T144212_2 - 5.4e-05 23.1 0.0 1.9 8.6 0.4 4.2 3 1 0 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.4 T144212_3 - 8.1e-06 25.7 0.0 0.15 12.0 0.1 4.3 3 1 0 3 3 3 2 Pentapeptide repeats (9 copies) DUF3704 PF12488.6 T260505_2 - 0.012 15.1 1.6 0.023 14.2 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Med19 PF10278.7 T238410_3 - 1.5 8.6 15.9 2.6 7.8 15.9 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF1145 PF06611.10 T203747_1 - 0.016 15.0 0.1 1.5 8.7 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) zf-CCHC PF00098.21 T379785_1 - 3e-06 26.9 2.5 8.2e-06 25.5 2.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.4 T379785_1 - 0.26 10.9 2.9 0.58 9.8 2.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Gag_p30 PF02093.14 T379785_2 - 0.00043 19.7 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Gag P30 core shell protein RVP PF00077.18 T379785_3 - 0.0039 17.3 0.0 0.0072 16.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1725 PF08333.9 T379785_3 - 0.032 13.8 2.3 0.068 12.7 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) DUF3299 PF11736.6 T011602_2 - 0.055 13.4 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) DUF971 PF06155.10 T185829_1 - 0.12 12.9 0.3 0.24 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Transposase_1 PF01359.16 T272252_2 - 1e-17 63.6 0.1 2.3e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) Wbp11 PF09429.8 T093960_1 - 0.1 12.8 8.7 0.21 11.8 8.7 1.4 1 0 0 1 1 1 0 WW domain binding protein 11 RVT_1 PF00078.25 T285177_3 - 1.7e-08 34.1 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-T_C PF15511.4 T323351_3 - 0.15 12.0 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF1652 PF07865.9 T373665_1 - 0.025 14.3 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) GP41 PF00517.15 T383568_1 - 1.5e-16 60.8 2.3 2.5e-16 60.0 2.3 1.3 1 0 0 1 1 1 1 Retroviral envelope protein HERV-K_env_2 PF13804.4 T383568_1 - 1e-05 25.2 0.1 1.8e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Retro-transcribing viruses envelope glycoprotein HERV-K_env_2 PF13804.4 T383568_2 - 5.4e-18 65.2 0.1 8.3e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Retro-transcribing viruses envelope glycoprotein NinF PF05810.10 T350882_1 - 0.062 13.0 0.9 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 NinF protein Transposase_22 PF02994.12 T181982_3 - 5.7e-26 91.1 7.9 8.6e-26 90.5 7.9 1.2 1 0 0 1 1 1 1 L1 transposable element Transposase_22 PF02994.12 T311319_2 - 1.1e-14 54.0 2.0 1.5e-08 33.8 0.2 2.3 2 0 0 2 2 2 2 L1 transposable element RVT_1 PF00078.25 T311319_3 - 3e-11 43.1 0.9 3e-11 43.1 0.9 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T030065_2 - 3.2e-06 26.5 0.3 5.7e-06 25.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T103658_1 - 6.2e-14 51.5 1.6 3.5e-13 49.0 1.6 2.0 1 1 0 1 1 1 1 L1 transposable element DUF1725 PF08333.9 T103658_2 - 0.021 14.3 2.1 0.051 13.1 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T103658_3 - 0.0014 18.0 0.5 0.0061 16.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.24 T315079_3 - 8.5e-09 35.5 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1725 PF08333.9 T158092_2 - 0.0014 18.1 0.1 0.0028 17.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) RVT_thumb PF06817.12 T303221_1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RVT_1 PF00078.25 T083749_1 - 8.7e-08 31.8 0.1 1.4e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 T083749_3 - 1.5e-12 47.4 0.4 8.6e-09 35.1 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) N-SET PF11764.6 T094266_3 - 0.29 11.1 6.1 0.036 14.0 2.3 1.5 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N Transposase_22 PF02994.12 T027114_1 - 1.8e-15 56.5 1.5 3.5e-15 55.6 1.5 1.3 1 0 0 1 1 1 1 L1 transposable element Transposase_22 PF02994.12 T027114_3 - 1.9e-05 23.6 1.7 2e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 L1 transposable element Toxin_18 PF08087.9 T163449_1 - 0.13 12.1 2.3 0.26 11.2 2.3 1.4 1 0 0 1 1 1 0 Conotoxin O-superfamily Gelsolin PF00626.20 T298371_3 - 0.099 12.4 0.1 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Gelsolin repeat PRAI PF00697.20 T013908_2 - 0.12 12.0 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase BH4 PF02180.15 T158608_2 - 0.59 9.9 0.0 0.59 9.9 0.0 2.4 4 0 0 4 4 4 0 Bcl-2 homology region 4 Gelsolin PF00626.20 T298378_2 - 0.11 12.3 0.1 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Gelsolin repeat zf-C3HC4_2 PF13923.4 T306087_1 - 0.064 13.0 0.3 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 T273565_3 - 0.00023 21.0 0.5 0.00055 19.8 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 T273565_3 - 0.025 14.6 0.5 0.059 13.4 0.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.4 T273565_3 - 0.037 13.7 0.4 0.092 12.5 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 T273565_3 - 0.051 13.3 0.3 0.14 11.9 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1725 PF08333.9 T296993_1 - 6.3e-07 28.8 1.1 1.5e-06 27.6 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) Orthopox_B11R PF07033.9 T296993_1 - 0.052 13.2 0.2 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Abhydro_lipase PF04083.14 T252013_2 - 0.083 12.4 0.6 6.9 6.2 0.0 2.8 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region Gag_p30 PF02093.14 T273336_1 - 0.051 12.9 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein zf-CCHC PF00098.21 T273336_3 - 0.16 12.0 6.6 0.027 14.4 1.7 2.4 2 0 0 2 2 2 0 Zinc knuckle Toxin_18 PF08087.9 T015874_1 - 0.32 10.9 2.3 0.65 9.9 2.3 1.5 1 0 0 1 1 1 0 Conotoxin O-superfamily RVT_1 PF00078.25 T224194_1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T224194_1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RNA_pol_Rpc4 PF05132.12 T224194_2 - 0.97 9.7 14.4 1.8 8.9 14.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Coilin_N PF15862.3 T224194_2 - 3.4 7.3 16.8 8.2 6.1 16.8 1.6 1 0 0 1 1 1 0 Coilin N-terminus DDHD PF02862.15 T224194_2 - 4.1 7.3 11.8 7 6.6 11.8 1.2 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.12 T224194_3 - 0.34 11.2 15.5 0.025 14.9 8.9 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF1510 PF07423.9 T224194_3 - 3.2 7.0 18.3 6.4 6.0 18.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Eapp_C PF10238.7 T224194_3 - 4.2 7.3 15.9 13 5.7 15.9 1.8 1 0 0 1 1 1 0 E2F-associated phosphoprotein 4HBT PF03061.20 T370209_1 - 0.056 13.7 0.3 47 4.3 0.0 3.6 4 0 0 4 4 4 0 Thioesterase superfamily 4HBT PF03061.20 T370209_2 - 0.00062 19.9 4.2 39 4.6 0.0 5.4 5 1 0 5 5 5 4 Thioesterase superfamily DUF4816 PF16086.3 T006299_1 - 0.72 9.7 23.7 0.013 15.3 15.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4816) Keratin_2_head PF16208.3 T006299_3 - 0.046 13.8 6.4 0.085 12.9 6.4 1.3 1 0 0 1 1 1 0 Keratin type II head DUF4816 PF16086.3 T006299_3 - 2.7 7.9 28.6 0.055 13.3 15.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4816) DUF1725 PF08333.9 T355070_3 - 1e-07 31.2 0.1 2e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Gag_p30 PF02093.14 T271501_2 - 0.00019 20.9 0.2 0.001 18.5 0.0 1.9 2 0 0 2 2 2 1 Gag P30 core shell protein zf-CCHC PF00098.21 T271501_2 - 0.002 18.0 0.8 0.0065 16.4 0.8 2.0 1 0 0 1 1 1 1 Zinc knuckle RNase_H PF00075.22 T271501_3 - 3.3e-11 43.5 0.0 5.1e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 RNase H DDE_1 PF03184.17 T333625_2 - 7.8e-11 41.7 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.14 T333625_3 - 1.2e-05 25.1 0.2 2.4e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HemY_N PF07219.11 T286956_2 - 2.2 8.4 4.5 4.1 7.5 4.5 1.3 1 0 0 1 1 1 0 HemY protein N-terminus UPF0154 PF03672.11 T104805_3 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) CDC45 PF02724.12 T068469_1 - 2.3 6.3 4.0 2.1 6.4 4.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.17 T068469_2 - 5.8 6.5 5.7 5.5 6.6 5.7 1.1 1 0 0 1 1 1 0 Connexin U79_P34 PF03064.14 T068469_3 - 0.13 11.5 8.3 0.12 11.6 8.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3464 PF11947.6 T068469_3 - 2.6 7.6 6.5 2.9 7.5 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Gmx_para_CXXCG PF09535.8 T106617_3 - 0.17 11.0 1.8 0.23 10.5 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) Alpha_E3_glycop PF01563.14 T127152_1 - 0.48 10.4 4.3 0.79 9.7 0.0 2.7 2 0 0 2 2 2 0 Alphavirus E3 glycoprotein Cleaved_Adhesin PF07675.9 T378290_1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Cleaved Adhesin Domain DUF3975 PF13126.4 T247461_1 - 3.5 8.0 7.6 0.28 11.5 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Pico_P2A PF00947.17 T310399_1 - 0.06 13.2 0.5 0.11 12.4 0.5 1.3 1 0 0 1 1 1 0 Picornavirus core protein 2A Transposase_22 PF02994.12 T310399_2 - 4.7e-16 58.5 15.1 5e-15 55.1 15.1 2.2 1 1 0 1 1 1 1 L1 transposable element DDE_1 PF03184.17 T297087_1 - 3.4e-19 69.0 0.2 1.2e-18 67.2 0.3 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.14 T297087_1 - 1.3e-09 37.9 0.2 1.3e-09 37.9 0.2 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF1725 PF08333.9 T297087_1 - 1.1e-06 28.0 0.3 2.4e-06 26.9 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) RseA_C PF03873.11 T219351_3 - 0.15 12.2 0.3 7 6.8 0.0 2.6 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain SspO PF08175.10 T329686_3 - 0.093 13.1 5.7 0.18 12.2 5.7 1.4 1 0 0 1 1 1 0 Small acid-soluble spore protein O family YcxB PF14317.4 T109901_1 - 0.13 11.6 0.2 0.26 10.6 0.2 1.5 1 0 0 1 1 1 0 YcxB-like protein Tnp_DNA_bind PF14706.4 T303663_3 - 0.087 12.6 0.2 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Transposase DNA-binding DUF1725 PF08333.9 T283546_1 - 2.3e-08 33.3 1.6 6.1e-08 32.0 1.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T354871_1 - 0.0027 17.2 0.1 0.0083 15.6 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Bradykinin PF06753.10 T190420_2 - 0.043 13.4 1.6 0.1 12.2 1.6 1.6 1 0 0 1 1 1 0 Bradykinin DUF2647 PF10839.6 T196423_2 - 0.074 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) DUF3915 PF13054.4 T283580_3 - 0.67 9.8 2.7 1.2 9.0 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) zf-FPG_IleRS PF06827.12 T295672_3 - 0.77 9.5 5.8 0.21 11.4 0.8 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Macin PF14865.4 T321423_1 - 0.021 15.2 1.4 0.077 13.4 1.4 2.0 1 0 0 1 1 1 0 Macin RVT_1 PF00078.25 T064407_1 - 4.9e-05 22.8 0.1 0.002 17.5 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T102452_1 - 2.9e-08 33.0 0.8 6e-08 32.0 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T102452_2 - 1.3e-80 270.9 19.0 6.9e-77 258.6 11.4 2.3 2 0 0 2 2 2 2 L1 transposable element RVT_1 PF00078.25 T102452_3 - 1.8e-33 115.8 1.3 1.8e-33 115.8 1.3 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_22 PF02994.12 T102452_3 - 7.4e-20 71.0 0.1 1.1e-19 70.4 0.1 1.2 1 0 0 1 1 1 1 L1 transposable element YjbT PF17089.3 T132627_1 - 0.15 11.9 1.3 7.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family FANCD2OS PF15124.4 T217064_1 - 0.21 11.7 0.9 0.31 11.1 0.9 1.2 1 0 0 1 1 1 0 FANCD2 opposite strand protein DUF1725 PF08333.9 T320741_2 - 1.3e-06 27.7 0.1 2.4e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) SVM_signal PF12113.6 T024013_2 - 0.3 10.9 1.7 0.54 10.1 1.7 1.3 1 0 0 1 1 1 0 SVM protein signal sequence YlqD PF11068.6 T164569_3 - 1.9 8.7 5.4 3.3 8.0 5.4 1.3 1 0 0 1 1 1 0 YlqD protein RVT_1 PF00078.25 T144147_1 - 2.4e-19 69.6 0.0 3.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 T144147_3 - 9.2e-06 25.2 1.0 1.4e-05 24.6 1.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3300 PF11737.6 T277108_3 - 0.013 14.9 0.0 3.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) DUF1725 PF08333.9 T220175_3 - 0.0023 17.4 0.8 0.0041 16.6 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Mucin-like PF16058.3 T259426_3 - 6.1e-12 45.4 8.1 0.005 16.7 0.1 5.2 2 2 0 3 3 3 3 Mucin-like DUF2080 PF09853.7 T259426_3 - 2.7 7.7 5.3 5.5e+02 0.3 0.0 5.6 5 0 0 5 5 5 0 Putative transposon-encoded protein (DUF2080) zf-A20 PF01754.14 T166499_3 - 0.061 13.2 0.4 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 A20-like zinc finger Pentapeptide_4 PF13599.4 T211000_1 - 0.2 11.7 2.4 2.1 8.4 0.8 2.4 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) Sigma70_r2 PF04542.12 T297439_2 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 region 2 HTH_Mga PF08280.9 T192519_2 - 0.041 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain MttA_Hcf106 PF02416.14 T082502_3 - 0.093 11.9 0.6 0.15 11.3 0.6 1.2 1 0 0 1 1 1 0 mttA/Hcf106 family DUF3704 PF12488.6 T007052_3 - 0.42 10.2 4.2 1.3 8.6 4.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Chlam_OMP3 PF03503.11 T343219_1 - 0.6 10.3 5.8 5.3 7.3 1.4 3.6 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 3 Atrophin-1 PF03154.13 T191714_1 - 1.7 6.7 3.9 2.4 6.2 3.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family FAM27 PF15832.3 T191714_3 - 0.4 11.1 3.9 0.74 10.3 3.9 1.3 1 0 0 1 1 1 0 FAM27 D and E protein family HxlR PF01638.15 T316929_1 - 0.55 10.0 5.7 1.3e+02 2.4 0.0 5.6 7 0 0 7 7 7 0 HxlR-like helix-turn-helix YhdB PF14148.4 T316929_1 - 3.7 7.6 10.3 1.1e+02 2.9 0.0 5.5 6 0 0 6 6 6 0 YhdB-like protein FAM27 PF15832.3 T174279_1 - 5.5e-15 55.5 69.4 2.3e-07 31.1 14.7 4.7 5 0 0 5 5 5 3 FAM27 D and E protein family FAM27 PF15832.3 T174279_2 - 2.7e-10 40.5 36.3 5.4e-09 36.3 17.9 3.8 3 0 0 3 3 3 2 FAM27 D and E protein family zf-CCHC PF00098.21 T174279_2 - 0.47 10.5 10.6 0.011 15.7 1.7 2.9 3 0 0 3 3 3 0 Zinc knuckle FAM27 PF15832.3 T174279_3 - 0.00038 20.8 11.1 0.00038 20.8 11.1 5.0 4 0 0 4 4 4 2 FAM27 D and E protein family DUF4710 PF15828.3 T174279_3 - 0.11 12.5 4.3 0.29 11.2 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) BacteriocIIc_cy PF12173.6 T285835_3 - 0.025 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like Vitelline_membr PF10542.7 T097048_1 - 0.12 12.1 0.3 0.24 11.2 0.3 1.4 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region DUF1725 PF08333.9 T255160_2 - 1.8e-06 27.3 1.6 3.9e-06 26.2 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) rve PF00665.24 T266912_1 - 2.1e-09 37.5 0.0 6.2e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 Integrase core domain RNase_H PF00075.22 T266912_2 - 0.00051 20.1 0.1 0.00087 19.4 0.1 1.2 1 0 0 1 1 1 1 RNase H TLV_coat PF00429.17 T266912_3 - 1.1e-05 24.3 0.2 1.6e-05 23.7 0.2 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) RVT_1 PF00078.25 T266912_3 - 0.00084 18.8 0.1 0.0021 17.5 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-B_N PF04218.11 T285922_3 - 0.028 13.9 0.5 0.075 12.5 0.5 1.8 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF1725 PF08333.9 T249534_2 - 1.2e-05 24.6 0.5 2.1e-05 23.9 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) zf-CCCH_2 PF14608.4 T097664_1 - 0.071 13.5 4.4 0.51 10.8 1.1 3.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger hNIFK_binding PF12196.6 T151649_3 - 0.08 12.4 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Humanin PF15040.4 T088999_2 - 0.6 9.6 2.1 1.2 8.6 2.1 1.5 1 0 0 1 1 1 0 Humanin family RHS PF03527.12 T354057_2 - 0.1 12.2 0.2 0.1 12.2 0.2 1.7 2 0 0 2 2 2 0 RHS protein Transposase_22 PF02994.12 T153377_2 - 0.00018 20.3 0.1 0.00026 19.9 0.1 1.1 1 0 0 1 1 1 1 L1 transposable element TMEM40 PF15817.3 T044499_2 - 1 9.0 4.7 2.1 7.9 4.7 1.4 1 0 0 1 1 1 0 Transmembrane protein 40 family DHBP_synthase PF00926.17 T296574_2 - 0.14 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF1924 PF09086.9 T381036_2 - 0.12 12.7 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) RHD_dimer PF16179.3 T065694_3 - 0.047 13.6 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Rel homology dimerisation domain DUF1725 PF08333.9 T295681_2 - 8.8e-07 28.3 0.5 1.6e-06 27.4 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) BAAT_C PF08840.9 T244435_3 - 0.01 15.6 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1725 PF08333.9 T253732_2 - 2.3e-07 30.2 0.1 4.2e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) HTH_Tnp_Tc5 PF03221.14 T122735_1 - 1.4e-07 31.3 0.2 2.3e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.11 T122735_2 - 8.8e-06 25.1 0.6 2e-05 24.0 0.2 1.8 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain DDE_1 PF03184.17 T122735_2 - 0.00019 20.9 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.17 T122735_3 - 1.7e-12 47.1 0.0 2.9e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1725 PF08333.9 T350974_3 - 2.7e-06 26.7 0.5 5.1e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) ATP-synt_8 PF00895.18 T344713_1 - 0.58 10.5 5.4 2 8.8 5.4 2.0 1 0 0 1 1 1 0 ATP synthase protein 8 DUF1725 PF08333.9 T103800_1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T315744_3 - 0.00046 19.6 2.0 0.0011 18.5 2.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1131 PF06572.10 T236124_3 - 0.21 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) STAC2_u1 PF16664.3 T129804_1 - 0.63 10.4 2.6 4.5 7.6 1.1 2.3 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF1725 PF08333.9 T378737_1 - 8.3e-08 31.5 1.1 1.8e-07 30.5 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Gag_MA PF01140.17 T379537_1 - 0.071 12.7 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Matrix protein (MA), p15 DUF4408 PF14364.4 T213384_1 - 0.088 12.4 3.9 0.27 10.9 3.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) Leader_Trp PF08255.9 T198038_2 - 0.064 13.1 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Trp-operon Leader Peptide Wound_ind PF08186.9 T083835_1 - 0.53 10.6 4.3 0.47 10.8 1.8 2.1 2 0 0 2 2 2 0 Wound-inducible basic protein family DUF1725 PF08333.9 T274659_1 - 0.012 15.1 0.6 0.028 14.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Colipase PF01114.16 T371089_1 - 0.047 13.2 1.1 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Colipase, N-terminal domain DUF1725 PF08333.9 T287706_1 - 0.039 13.5 0.1 0.039 13.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T221922_2 - 9.2e-08 31.4 0.1 2e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DAP_epimerase PF01678.17 T221922_3 - 0.14 12.2 0.2 0.25 11.4 0.2 1.3 1 0 0 1 1 1 0 Diaminopimelate epimerase RVT_1 PF00078.25 T159449_1 - 8.5e-07 28.6 2.1 1.5e-06 27.7 2.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TLV_coat PF00429.17 T268558_1 - 0.0025 16.4 0.0 0.0044 15.6 0.0 1.3 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) FAM27 PF15832.3 T289606_3 - 0.13 12.7 7.3 0.26 11.7 7.3 1.5 1 0 0 1 1 1 0 FAM27 D and E protein family DUF1725 PF08333.9 T246688_1 - 3.7e-07 29.5 0.8 9.5e-07 28.2 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Exo_endo_phos_2 PF14529.4 T246688_1 - 0.00012 21.7 0.9 0.00038 20.2 0.9 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase UBD PF16455.3 T246688_1 - 0.12 12.4 0.6 0.26 11.4 0.6 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain Exo_endo_phos PF03372.21 T246688_2 - 0.00035 20.7 0.0 0.00066 19.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Toxin_25 PF08095.9 T103434_1 - 4.3 7.2 5.9 7.2 6.5 5.9 1.3 1 0 0 1 1 1 0 Hefutoxin family DUF594 PF04578.11 T254188_2 - 0.12 11.8 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF594 DUF1725 PF08333.9 T359889_3 - 4.6e-07 29.2 0.8 1e-06 28.1 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF4887 PF16228.3 T348879_1 - 0.71 9.6 14.3 1.3 8.7 14.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) FAR1 PF03101.13 T348879_1 - 1.2 9.8 4.5 2.9 8.6 4.5 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF1725 PF08333.9 T116544_3 - 6.2e-06 25.6 0.1 1.2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Glucokinase PF02685.14 T108857_2 - 0.032 13.1 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Glucokinase DUF1725 PF08333.9 T290867_2 - 3.8e-06 26.3 0.2 6.9e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF2475 PF10629.7 T183190_1 - 0.96 9.6 8.4 14 5.9 3.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2475) DUF966 PF06136.11 T183190_3 - 2.8 7.4 10.3 3.5 7.1 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MFMR_assoc PF16596.3 T183190_3 - 3 8.2 6.5 3.3 8.1 6.0 1.3 1 1 0 1 1 1 0 Disordered region downstream of MFMR DUF1725 PF08333.9 T287703_2 - 0.032 13.8 0.1 0.032 13.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T027265_1 - 6.7e-13 48.5 0.7 1.1e-12 47.8 0.7 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T066129_1 - 7.2e-07 28.6 0.2 2.2e-06 27.0 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T030070_2 - 2.6e-06 26.8 0.3 4.5e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Baculo_11_kDa PF06143.9 T185232_2 - 3.6 7.1 6.9 7.6 6.1 6.9 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family WSK PF03832.11 T221716_3 - 0.13 11.8 2.3 0.1 12.2 0.5 1.8 2 0 0 2 2 2 0 WSK motif FAM27 PF15832.3 T167751_1 - 0.00014 22.1 10.4 0.00014 22.1 10.4 2.3 2 0 0 2 2 2 1 FAM27 D and E protein family DUF3915 PF13054.4 T167751_1 - 0.0098 15.7 0.5 0.0098 15.7 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) FAM27 PF15832.3 T167751_2 - 0.00021 21.6 14.0 0.00021 21.6 14.0 2.1 2 0 0 2 2 2 1 FAM27 D and E protein family DUF3915 PF13054.4 T167751_2 - 0.0048 16.7 2.5 0.0048 16.7 2.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) FAM27 PF15832.3 T167751_3 - 6e-05 23.4 11.9 0.00017 21.9 11.9 1.7 1 0 0 1 1 1 1 FAM27 D and E protein family DUF3915 PF13054.4 T167751_3 - 0.039 13.8 5.8 0.1 12.5 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF1725 PF08333.9 T167751_3 - 0.68 9.5 3.1 1.2 8.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Transposase_1 PF01359.16 T081638_1 - 0.00017 21.3 0.9 0.00037 20.1 0.9 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) Transposase_1 PF01359.16 T081638_3 - 1.4e-21 76.0 0.1 2.4e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) Transposase_1 PF01359.16 T161073_3 - 2.2e-06 27.3 0.0 5.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) C1_1 PF00130.20 T122872_3 - 0.0083 15.9 4.5 0.1 12.4 0.7 2.8 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) RVT_1 PF00078.25 T315263_3 - 3e-14 53.0 0.1 4.6e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_22 PF02994.12 T282178_2 - 7.3e-06 24.9 2.0 1e-05 24.5 2.0 1.1 1 0 0 1 1 1 1 L1 transposable element DUF1725 PF08333.9 T072226_2 - 6.1e-05 22.4 0.6 0.00018 20.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T072226_3 - 6.2e-08 32.0 0.8 6.2e-08 32.0 0.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) Atrophin-1 PF03154.13 T277952_1 - 7.2 4.6 5.1 9.6 4.2 5.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family Adeno_E3_CR2 PF02439.13 T261463_2 - 5.4 6.7 8.3 0.23 11.1 1.8 2.0 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 YdjO PF14169.4 T265660_2 - 0.0041 16.7 0.1 0.0096 15.5 0.1 1.6 1 0 0 1 1 1 1 Cold-inducible protein YdjO DUF3915 PF13054.4 T265660_3 - 6.2 6.7 8.6 12 5.7 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) GCSF PF16647.3 T094188_2 - 0.064 13.0 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor DUF3678 PF12435.6 T150111_3 - 0.3 10.2 4.4 0.17 11.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) WBP-1 PF11669.6 T227669_3 - 0.23 12.0 1.8 0.29 11.6 0.4 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF1725 PF08333.9 T015738_1 - 3.6e-07 29.5 0.7 7.1e-07 28.6 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T015738_2 - 4.3e-11 42.6 0.1 7.8e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 T345312_1 - 0.00013 21.4 0.0 0.00097 18.6 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rrn6 PF10214.7 T260585_1 - 1.4 7.1 7.6 1.9 6.7 7.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4746 PF15928.3 T260585_1 - 9.7 5.4 10.6 14 4.9 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TLV_coat PF00429.17 T314781_3 - 0.00019 20.2 0.9 0.00082 18.0 0.6 1.9 2 0 0 2 2 2 1 ENV polyprotein (coat polyprotein) Yae1_N PF09811.7 T036407_1 - 0.043 13.4 5.1 0.098 12.2 5.1 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.7 T036407_2 - 1.3 8.6 4.5 2.6 7.7 4.5 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.7 T036407_3 - 0.14 11.7 1.7 0.26 10.9 1.7 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Transposase_22 PF02994.12 T153311_3 - 5.3e-46 157.0 0.5 8e-46 156.4 0.5 1.2 1 0 0 1 1 1 1 L1 transposable element Tnp_DNA_bind PF14706.4 T288907_3 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Transposase DNA-binding DUF5121 PF17165.2 T208865_2 - 0.1 12.9 0.4 0.24 11.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5121) Antimicrobial_6 PF08036.9 T208865_2 - 0.94 9.5 4.4 2.8 7.9 4.4 1.8 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide Toxin_18 PF08087.9 T060552_2 - 3.1 7.7 5.9 0.9 9.5 2.1 2.1 2 0 0 2 2 2 0 Conotoxin O-superfamily VitD-bind_III PF09164.8 T039224_3 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF1777 PF08648.10 T378327_2 - 1.4 9.0 30.5 2.1 8.4 30.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF1725 PF08333.9 T224361_3 - 6.6e-09 35.0 0.8 1.8e-08 33.7 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) CCDC71L PF15374.4 T316660_3 - 0.77 8.8 4.4 1 8.4 4.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Bradykinin PF06753.10 T086844_3 - 0.23 11.1 2.6 0.84 9.3 2.6 2.0 1 0 0 1 1 1 0 Bradykinin Gag_p30 PF02093.14 T089147_1 - 1.7e-14 53.8 0.0 2.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Gag P30 core shell protein RVT_1 PF00078.25 T089147_1 - 2.5e-07 30.3 0.0 4.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.21 T089147_1 - 5e-06 26.2 1.0 1.3e-05 24.9 1.0 1.8 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.18 T089147_1 - 0.00029 20.9 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_5 PF14787.4 T089147_1 - 0.032 13.8 2.7 0.074 12.6 2.7 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RNase_H PF00075.22 T089147_3 - 4.2e-15 56.1 0.1 6.5e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 RNase H TLV_coat PF00429.17 T089147_3 - 1.7e-12 46.7 0.3 1.7e-12 46.7 0.3 2.0 2 0 0 2 2 2 1 ENV polyprotein (coat polyprotein) BC10 PF06726.10 T338678_1 - 0.044 13.9 0.1 0.068 13.3 0.1 1.2 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 CDC45 PF02724.12 T242559_3 - 5.3 5.1 5.7 5.5 5.0 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1725 PF08333.9 T082049_1 - 0.00024 20.6 1.0 0.00059 19.3 1.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T082049_2 - 5.8e-26 91.1 0.8 8.8e-26 90.5 0.8 1.2 1 0 0 1 1 1 1 L1 transposable element DUF1725 PF08333.9 T082049_3 - 7e-05 22.2 0.4 0.00018 20.9 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Stm1_N PF09598.8 T062347_3 - 0.042 14.6 0.4 0.1 13.3 0.4 1.6 1 0 0 1 1 1 0 Stm1 Eapp_C PF10238.7 T132100_3 - 0.22 11.5 0.0 0.22 11.5 0.0 4.2 4 0 0 4 4 4 0 E2F-associated phosphoprotein RVT_1 PF00078.25 T272544_1 - 2.1e-09 37.1 0.1 3.4e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_22 PF02994.12 T272544_2 - 1.3e-38 132.7 0.1 1.3e-38 132.7 0.1 2.8 2 1 0 2 2 2 1 L1 transposable element Transposase_22 PF02994.12 T272544_3 - 4.4e-47 160.6 14.3 5.6e-46 156.9 2.2 2.3 2 0 0 2 2 2 2 L1 transposable element RVT_1 PF00078.25 T272544_3 - 4.7e-29 101.4 0.4 8.6e-29 100.5 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T272544_3 - 4.1e-08 32.5 0.7 1.4e-07 30.8 0.7 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Exo_endo_phos_2 PF14529.4 T272544_3 - 0.00011 21.9 1.2 0.00027 20.6 1.2 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.21 T272544_3 - 0.081 13.1 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF4939 PF16297.3 T158036_2 - 0.02 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DUF4939 PF16297.3 T158036_3 - 5.2e-11 42.3 0.0 9.9e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF3704 PF12488.6 T001940_2 - 0.00018 20.9 1.9 0.00047 19.6 1.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3704) Transposase_22 PF02994.12 T127198_1 - 9.2e-99 330.6 7.8 1.3e-98 330.1 7.8 1.1 1 0 0 1 1 1 1 L1 transposable element zf-H2C2 PF09337.8 T127198_1 - 9.8e-05 22.4 0.1 0.00026 21.1 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Exo_endo_phos PF03372.21 T127198_1 - 0.055 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF1725 PF08333.9 T127198_2 - 0.0032 17.0 0.6 0.0061 16.1 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T127198_3 - 1.4e-23 83.5 0.4 2e-23 83.0 0.4 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.24 T127198_3 - 1e-07 32.0 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Gag_p30 PF02093.14 T217273_1 - 6.3e-12 45.3 0.0 1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Gag P30 core shell protein DUF3915 PF13054.4 T097011_1 - 0.99 9.3 5.6 1.7 8.5 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 T097011_1 - 7.2 4.6 12.1 9.6 4.2 12.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family AA_permease_N PF08403.8 T266343_3 - 0.027 13.9 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF1725 PF08333.9 T010446_2 - 1.6e-08 33.8 0.1 3.1e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) 2Fe-2S_Ferredox PF11591.6 T034618_2 - 0.62 9.8 2.4 1.1 9.1 2.4 1.3 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide DUF1725 PF08333.9 T157818_1 - 8.3e-09 34.7 0.8 8.3e-09 34.7 0.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) DDE_1 PF03184.17 T157818_1 - 8.9e-09 35.0 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1725 PF08333.9 T324336_2 - 6.7e-08 31.9 0.8 1.2e-07 31.0 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) TSP_1 PF00090.17 T272147_3 - 0.94 9.6 7.8 0.11 12.6 2.4 2.4 2 0 0 2 2 2 0 Thrombospondin type 1 domain Thionin PF00321.15 T258777_2 - 1.2 9.6 4.8 20 5.6 0.2 2.4 2 0 0 2 2 2 0 Plant thionin RVT_1 PF00078.25 T039252_1 - 4.8e-18 65.3 0.8 9.1e-18 64.4 0.8 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.4 T039252_1 - 9.9e-05 22.0 0.1 0.00024 20.8 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Transposase_22 PF02994.12 T039252_2 - 3.5e-68 230.0 20.7 2.3e-67 227.3 9.2 3.1 3 0 0 3 3 3 2 L1 transposable element HSBP1 PF06825.10 T039252_2 - 0.0083 15.9 0.9 0.017 14.9 0.9 1.5 1 0 0 1 1 1 1 Heat shock factor binding protein 1 NPV_P10 PF05531.10 T039252_2 - 4.5 7.7 5.5 1.2 9.5 1.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.25 T039252_3 - 4.9e-10 39.2 0.0 8.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHH PF10283.7 T039252_3 - 0.1 12.6 2.4 0.27 11.2 2.4 1.8 1 0 0 1 1 1 0 Zinc-finger (CX5CX6HX5H) motif DUF4366 PF14283.4 T022784_2 - 0.00094 18.6 0.1 0.0016 17.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Radial_spoke PF04712.10 T022784_2 - 0.42 9.4 3.1 0.6 8.8 3.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Ig_3 PF13927.4 T022784_3 - 0.0096 16.4 0.0 2.5 8.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain DUF3525 PF12039.6 T340404_3 - 0.034 12.7 0.1 0.044 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) DUF1725 PF08333.9 T311337_1 - 1.5e-05 24.4 1.1 2.9e-05 23.4 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T263163_2 - 6.1 6.5 5.8 0.42 10.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) zf-CCHC PF00098.21 T354923_1 - 1.2e-05 25.0 3.9 2.9e-05 23.8 3.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Gag_p30 PF02093.14 T354923_2 - 0.033 13.6 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein Mit_proteolip PF08039.9 T028894_1 - 0.00018 21.7 1.5 0.00037 20.6 1.5 1.5 1 0 0 1 1 1 1 Mitochondrial proteolipid Transposase_22 PF02994.12 T212682_3 - 0.00074 18.4 6.6 0.0012 17.6 6.6 1.3 1 0 0 1 1 1 1 L1 transposable element FlaC_arch PF05377.9 T212682_3 - 0.1 12.9 5.4 1.6 9.0 3.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.11 T212682_3 - 0.13 12.8 5.8 0.32 11.5 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) COMP PF11598.6 T212682_3 - 2.4 8.5 5.3 0.63 10.4 1.8 1.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein ARL6IP6 PF15062.4 T052795_2 - 0.072 13.1 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Fimbrillin_C PF15495.4 T339451_2 - 0.16 12.3 0.6 0.38 11.1 0.6 1.6 1 1 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal DUF3323 PF11796.6 T235003_2 - 0.037 13.8 0.3 0.056 13.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) rve PF00665.24 T174329_2 - 2.1e-20 72.9 0.0 3.6e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.22 T174329_2 - 1.9e-12 47.5 0.0 3.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 RNase H zf-H2C2 PF09337.8 T174329_2 - 5.8e-05 23.1 0.1 0.00013 22.1 0.1 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Stomagen PF16851.3 T176364_2 - 0.1 12.5 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Stomagen FAM27 PF15832.3 T378827_2 - 0.042 14.3 2.4 0.068 13.6 2.4 1.2 1 0 0 1 1 1 0 FAM27 D and E protein family DUF4684 PF15736.3 T084294_3 - 0.29 9.8 7.1 0.42 9.2 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) RVT_1 PF00078.25 T050214_1 - 7.4e-18 64.7 1.3 1.1e-17 64.2 1.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 T050214_3 - 9.6e-13 48.0 0.1 1.5e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4519 PF15012.4 T098845_1 - 5.4 7.1 4.9 13 5.9 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF1725 PF08333.9 T372997_3 - 0.19 11.3 1.2 0.31 10.6 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) F-box PF00646.31 T161093_1 - 0.019 14.7 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 F-box domain LisH_2 PF16045.3 T082473_3 - 0.14 11.1 4.1 3.4 6.7 0.5 2.6 2 0 0 2 2 2 0 LisH DUF1725 PF08333.9 T204132_1 - 0.13 11.8 0.1 0.35 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RVT_thumb PF06817.12 T112895_1 - 1.5e-23 82.2 0.3 3e-23 81.2 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVT_1 PF00078.25 T112895_1 - 2.6e-13 49.9 0.0 4.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.22 T112895_1 - 0.006 16.7 0.6 0.45 10.6 0.0 2.3 2 0 0 2 2 2 1 RNase H RVP PF00077.18 T112895_2 - 1.7e-22 79.5 0.2 3.1e-22 78.6 0.2 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.24 T112895_2 - 1.9e-12 47.3 0.0 3.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain IN_DBD_C PF00552.19 T112895_2 - 8.4e-06 24.9 3.2 1.7e-05 23.9 1.2 2.4 2 0 0 2 2 2 1 Integrase DNA binding domain Integrase_Zn PF02022.17 T112895_3 - 2e-11 43.5 0.2 5.3e-11 42.1 0.2 1.8 1 0 0 1 1 1 1 Integrase Zinc binding domain RVT_1 PF00078.25 T112895_3 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) dUTPase PF00692.17 T112895_3 - 3.8e-06 26.5 0.0 7.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 dUTPase HERV-K_REC PF15695.3 T112895_3 - 0.0011 18.8 0.9 0.0025 17.7 0.9 1.6 1 0 0 1 1 1 1 Rec (regulator of expression encoded by corf) of HERV-K-113 RNase_H PF00075.22 T112895_3 - 0.0026 17.9 0.2 0.0058 16.7 0.0 1.7 2 0 0 2 2 2 1 RNase H rve PF00665.24 T112895_3 - 0.012 15.7 0.0 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain HERV-K_env_2 PF13804.4 T112895_3 - 0.058 13.0 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein OST-HTH PF12872.5 T293305_1 - 0.006 16.3 0.1 1.1e+02 2.7 0.0 4.7 5 0 0 5 5 5 0 OST-HTH/LOTUS domain DUF3556 PF12077.6 T293305_1 - 0.016 13.5 0.4 4.5 5.4 0.0 3.5 1 1 3 4 4 4 0 Transmembrane protein of unknown function (DUF3556) OST-HTH PF12872.5 T293305_2 - 0.044 13.6 0.2 1.6e+02 2.2 0.0 4.0 4 0 0 4 4 4 0 OST-HTH/LOTUS domain OST-HTH PF12872.5 T293305_3 - 0.04 13.7 0.1 1.8e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 OST-HTH/LOTUS domain DUF1725 PF08333.9 T039465_2 - 1.9e-08 33.6 0.4 3.4e-08 32.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Exo_endo_phos PF03372.21 T378386_1 - 0.056 13.6 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF1725 PF08333.9 T383581_1 - 0.1 12.2 1.1 0.22 11.1 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) EMI PF07546.11 T130291_2 - 1.1 9.9 10.4 8 7.2 0.1 3.6 3 0 0 3 3 3 0 EMI domain BpuSI_N PF15516.4 T157342_2 - 0.017 15.0 2.7 47 3.9 0.3 4.7 5 0 0 5 5 5 0 BpuSI N-terminal domain Toxin_18 PF08087.9 T174308_2 - 0.00057 19.7 1.9 0.05 13.5 0.2 3.1 2 0 0 2 2 2 2 Conotoxin O-superfamily rve PF00665.24 T174308_3 - 5e-20 71.7 0.0 8.1e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.22 T174308_3 - 4.3e-12 46.3 0.0 6.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 RNase H zf-H2C2 PF09337.8 T174308_3 - 0.00011 22.2 0.1 0.00027 21.0 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.25 T183279_3 - 4.9e-18 65.3 1.7 1.1e-17 64.1 1.7 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TSP_1 PF00090.17 T272117_2 - 0.042 13.9 3.1 0.15 12.2 3.1 2.0 1 0 0 1 1 1 0 Thrombospondin type 1 domain Mit_proteolip PF08039.9 T209148_1 - 0.041 14.1 0.2 0.074 13.3 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial proteolipid Mrr_N PF14338.4 T283940_3 - 0.16 12.0 0.2 3.6 7.7 0.1 2.1 1 1 1 2 2 2 0 Mrr N-terminal domain DUF1725 PF08333.9 T291740_3 - 4.6e-07 29.2 1.0 9e-07 28.3 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T191436_2 - 0.032 13.8 0.4 0.049 13.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T194801_1 - 5.6e-22 78.0 8.6 1e-21 77.1 8.6 1.3 1 0 0 1 1 1 1 L1 transposable element RVT_1 PF00078.25 T194801_1 - 1.3e-06 28.0 1.2 2e-06 27.4 1.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_22 PF02994.12 T194801_2 - 6.7e-94 314.6 15.6 8.7e-69 232.0 8.8 3.2 3 0 0 3 3 3 2 L1 transposable element DUF1725 PF08333.9 T194801_2 - 0.0088 15.6 0.3 0.018 14.6 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF3915 PF13054.4 T132295_1 - 0.0064 16.3 2.8 0.0064 16.3 2.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) FAM27 PF15832.3 T132295_1 - 0.71 10.3 5.7 1.5 9.3 5.7 1.4 1 0 0 1 1 1 0 FAM27 D and E protein family DUF3915 PF13054.4 T132295_2 - 2.6 7.9 11.8 5.9 6.8 11.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 T132295_2 - 4.7 5.2 14.7 6.5 4.8 14.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 T132295_3 - 0.00052 19.9 1.6 0.0012 18.7 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 T132295_3 - 0.75 7.9 12.8 1.1 7.4 12.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family FAM27 PF15832.3 T132295_3 - 5.3 7.5 9.3 15 6.1 9.3 1.7 1 0 0 1 1 1 0 FAM27 D and E protein family Herpes_pp38 PF04846.11 T175009_1 - 0.1 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Transposase_22 PF02994.12 T109509_1 - 1.3e-15 57.1 0.0 2.8e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 L1 transposable element DUF1725 PF08333.9 T109509_1 - 0.01 15.3 0.0 0.031 13.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) RVT_1 PF00078.25 T109509_3 - 5.5e-31 107.7 1.3 9.4e-31 106.9 1.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_22 PF02994.12 T109509_3 - 1.5e-22 79.8 16.5 1.5e-22 79.8 16.5 2.4 2 1 0 2 2 2 1 L1 transposable element Exo_endo_phos_2 PF14529.4 T109509_3 - 0.029 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF3704 PF12488.6 T075971_3 - 0.036 13.6 2.2 0.088 12.4 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Rrn6 PF10214.7 T275391_2 - 0.79 7.9 9.4 1.3 7.2 9.4 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TLV_coat PF00429.17 T003335_3 - 0.0013 17.4 2.9 0.0018 16.9 2.9 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) FATC PF02260.18 T191966_1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 FATC domain Keratin_2_head PF16208.3 T294072_2 - 0.7 9.9 13.7 1.1 9.3 13.7 1.2 1 0 0 1 1 1 0 Keratin type II head Atrophin-1 PF03154.13 T294072_3 - 0.51 8.4 16.3 0.78 7.8 16.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 T294072_3 - 0.73 9.7 9.8 1.2 9.0 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF1725 PF08333.9 T375406_3 - 2.7e-06 26.7 0.1 4.6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) BacteriocIIc_cy PF12173.6 T285840_1 - 0.031 14.4 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like TSKS PF15358.4 T023651_3 - 0.18 10.0 0.0 0.27 9.4 0.0 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Spt20 PF12090.6 T087033_3 - 0.11 12.0 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF1725 PF08333.9 T098913_3 - 2.9e-08 33.0 0.8 5.9e-08 32.0 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF1725 PF08333.9 T149071_3 - 0.0021 17.5 0.5 0.004 16.6 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Hyd_WA PF06462.10 T348560_2 - 0.091 12.6 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Propeller DUF2704 PF10866.6 T360186_3 - 0.081 12.7 0.5 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) DUF2768 PF10966.6 T137839_1 - 5.8 7.3 7.2 5 7.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2768) RVT_1 PF00078.25 T305500_1 - 7.1e-21 74.6 4.5 1.3e-20 73.8 4.5 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Toxin_18 PF08087.9 T259305_3 - 0.34 10.8 4.1 0.44 10.5 2.1 2.3 2 0 0 2 2 2 0 Conotoxin O-superfamily DUF1725 PF08333.9 T264252_2 - 6.6e-07 28.7 0.7 1.4e-06 27.7 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Wzy_C PF04932.13 T148568_1 - 6.5 6.2 13.9 0.41 10.1 6.0 2.4 3 0 0 3 3 3 0 O-Antigen ligase DUF1725 PF08333.9 T315745_1 - 0.00031 20.2 2.0 0.00078 18.9 2.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Filaggrin PF03516.11 T211030_2 - 8.5 7.1 12.4 0.46 11.1 4.2 3.3 2 0 0 2 2 2 0 Filaggrin SLC3A2_N PF16028.3 T133904_1 - 0.15 11.5 2.4 0.35 10.3 2.4 1.5 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus MSP1b PF03429.11 T183306_3 - 0.013 13.5 0.2 0.11 10.5 0.1 2.1 1 1 1 2 2 2 0 Major surface protein 1B rve PF00665.24 T006991_1 - 9.7e-20 70.8 0.0 2.4e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.25 T006991_1 - 7.6e-12 45.1 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.22 T006991_1 - 7e-05 22.9 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 RNase H Gag_p30 PF02093.14 T006991_2 - 1.9e-21 76.4 0.0 2.9e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Gag P30 core shell protein RVP PF00077.18 T006991_2 - 3.4e-05 23.9 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease TLV_coat PF00429.17 T006991_3 - 1.8e-07 30.1 0.8 2.6e-07 29.6 0.8 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Glyco_transf_4 PF13439.4 T147481_3 - 0.052 13.4 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF1725 PF08333.9 T313325_3 - 1.9e-05 24.0 1.3 3.7e-05 23.1 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) TLV_coat PF00429.17 T361340_1 - 3.6e-21 75.3 0.2 4.2e-21 75.1 0.2 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) DUF1725 PF08333.9 T245840_3 - 0.015 14.9 1.4 0.027 14.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) FAM27 PF15832.3 T213896_1 - 1.2e-05 25.6 10.3 2.4e-05 24.6 10.3 1.4 1 0 0 1 1 1 1 FAM27 D and E protein family DUF3915 PF13054.4 T213896_1 - 0.038 13.8 4.0 0.075 12.9 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 T213896_1 - 0.15 10.2 6.2 0.21 9.7 6.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF4816 PF16086.3 T213896_1 - 3 7.8 12.9 9.8 6.1 1.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4816) FAM27 PF15832.3 T213896_2 - 0.00016 22.0 14.6 0.00029 21.2 14.6 1.3 1 0 0 1 1 1 1 FAM27 D and E protein family DUF3915 PF13054.4 T213896_2 - 0.092 12.6 7.8 0.21 11.4 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 T213896_2 - 0.55 8.3 10.8 0.76 7.8 10.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family FAM27 PF15832.3 T213896_3 - 5.3e-05 23.6 12.8 9.8e-05 22.7 12.8 1.3 1 0 0 1 1 1 1 FAM27 D and E protein family DUF3915 PF13054.4 T213896_3 - 0.12 12.3 4.6 0.23 11.3 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 T213896_3 - 0.25 9.5 6.9 0.36 8.9 6.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1725 PF08333.9 T197483_1 - 3.5e-08 32.7 0.7 8e-08 31.6 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Transposase_22 PF02994.12 T197483_2 - 3.8e-112 374.7 23.0 3.6e-104 348.4 15.2 3.2 3 0 0 3 3 3 2 L1 transposable element Syntaxin-6_N PF09177.9 T197483_2 - 0.023 15.1 2.6 0.058 13.8 2.6 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Transposase_22 PF02994.12 T197483_3 - 2.2e-18 66.1 2.9 2.2e-18 66.1 2.9 1.5 2 0 0 2 2 2 1 L1 transposable element Antimicrobial_2 PF08023.10 T197483_3 - 1.3 9.5 3.8 2.5 8.6 3.8 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide DDE_1 PF03184.17 T266250_3 - 1.1e-20 73.8 0.0 5.3e-15 55.3 0.1 2.9 2 1 0 2 2 2 2 DDE superfamily endonuclease ATP_synt_H PF05493.11 T235563_3 - 1.2 9.6 5.9 0.21 11.9 0.9 2.2 2 0 0 2 2 2 0 ATP synthase subunit H Bradykinin PF06753.10 T066181_2 - 0.74 9.5 2.6 1.3 8.7 2.6 1.4 1 0 0 1 1 1 0 Bradykinin Imm-NTF2-2 PF15631.4 T109524_1 - 0.057 13.5 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein HERV-K_env_2 PF13804.4 T249657_1 - 7.2e-05 22.5 0.1 0.00013 21.7 0.1 1.3 1 0 0 1 1 1 1 Retro-transcribing viruses envelope glycoprotein IN_DBD_C PF00552.19 T249657_2 - 2.4e-05 23.4 0.0 4.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Integrase DNA binding domain HERV-K_REC PF15695.3 T249657_2 - 5.2e-05 23.1 0.5 0.0001 22.2 0.5 1.4 1 0 0 1 1 1 1 Rec (regulator of expression encoded by corf) of HERV-K-113 RNase_H PF00075.22 T249657_2 - 0.024 14.7 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 RNase H DUF2632 PF10943.6 T044665_3 - 0.021 14.3 0.3 0.034 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) DUF1725 PF08333.9 T011961_1 - 3.7e-05 23.1 0.0 6.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF2615 PF11027.6 T283674_1 - 0.0062 16.5 1.4 0.52 10.4 0.6 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2615) DUF1510 PF07423.9 T283674_1 - 0.018 14.4 0.3 0.02 14.2 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1180 PF06679.10 T283674_1 - 0.022 15.1 11.9 0.03 14.6 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SpoIIIAH PF12685.5 T283674_1 - 0.049 13.3 7.0 0.06 13.0 7.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF912 PF06024.10 T283674_1 - 0.052 13.7 2.4 0.051 13.7 0.6 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4064 PF13273.4 T283674_1 - 0.29 11.4 15.8 6.5 7.0 15.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2207 PF09972.7 T283674_1 - 0.32 9.6 8.1 0.38 9.3 8.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMCO5 PF14992.4 T283674_1 - 0.36 10.2 1.2 0.38 10.2 1.2 1.2 1 0 0 1 1 1 0 TMCO5 family CobT PF06213.10 T283674_1 - 0.42 9.8 2.8 0.49 9.6 2.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BatD PF13584.4 T283674_1 - 2.1 7.0 12.4 0.22 10.3 8.2 1.5 1 1 1 2 2 2 0 Oxygen tolerance Plasmodium_Vir PF05795.9 T283674_1 - 2.2 7.5 13.5 2.7 7.2 13.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TMEM154 PF15102.4 T283674_1 - 6 6.6 12.4 0.046 13.5 3.9 1.7 1 1 1 2 2 2 0 TMEM154 protein family Zip PF02535.20 T221794_2 - 4.7 6.2 23.0 6.7 5.7 23.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C23 PF05379.9 T373529_2 - 0.19 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Carlavirus endopeptidase Baculo_IE-1 PF05290.9 T001276_3 - 0.11 12.4 0.3 20 5.0 0.1 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) RVT_1 PF00078.25 T210801_1 - 6.5e-15 55.1 0.1 1e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.9 T210801_3 - 0.00028 20.3 0.5 0.0011 18.5 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1725) HERV-K_REC PF15695.3 T059383_3 - 0.14 12.1 0.2 0.22 11.5 0.2 1.2 1 0 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 Asp_protease_2 PF13650.4 T379143_1 - 0.0041 17.6 0.0 0.0069 16.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.4 T379143_1 - 0.0095 16.3 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.18 T379143_1 - 0.038 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease FAM27 PF15832.3 T037531_1 - 0.00043 20.6 9.0 0.00072 19.9 9.0 1.3 1 0 0 1 1 1 1 FAM27 D and E protein family FAM27 PF15832.3 T037531_2 - 0.0015 18.9 8.6 0.0015 18.9 8.6 1.6 2 0 0 2 2 2 1 FAM27 D and E protein family FAM27 PF15832.3 T037531_3 - 7.8e-06 26.2 5.2 1.3e-05 25.5 5.2 1.3 1 0 0 1 1 1 1 FAM27 D and E protein family Transposase_22 PF02994.12 T057874_1 - 0.0051 15.6 0.4 0.0051 15.6 0.4 1.5 2 0 0 2 2 2 1 L1 transposable element DUF1725 PF08333.9 T360423_1 - 6.7e-08 31.8 0.4 1.5e-07 30.7 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) TetR_C_12 PF16914.3 T296901_3 - 0.034 14.1 0.2 0.054 13.5 0.2 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal # # Program: hmmscan # Version: 3.1b2 (February 2015) # Pipeline mode: SCAN # Query file: /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/random5k/mitrans_lncRNA/wd/mitrans_lncRNA_5000.p.fa # Target file: /home/yduan/database/Pfam/Pfam-A.hmm # Option settings: hmmscan -o /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/random5k/mitrans_lncRNA/hmmscan.outm --tblout /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/random5k/mitrans_lncRNA/hmmscan.t.out /home/yduan/database/Pfam/Pfam-A.hmm /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/random5k/mitrans_lncRNA/wd/mitrans_lncRNA_5000.p.fa # Current dir: /home/yduan/work_file/lncRNAdb/methods_assement # Date: Tue Jul 3 07:12:33 2018 # [ok]