# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF1168 PF06658.10 MSTRG.76289.1_1 - 3e-43 146.8 18.1 3.4e-43 146.6 18.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF4407 PF14362.4 MSTRG.76289.1_1 - 0.036 13.3 3.3 0.047 12.9 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF755 PF05501.9 MSTRG.76289.1_1 - 0.036 14.2 10.8 0.044 13.9 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) HHA PF05321.9 MSTRG.76289.1_1 - 0.071 13.3 1.9 0.11 12.7 1.5 1.5 1 1 0 1 1 1 0 Haemolysin expression modulating protein RNA_pol_3_Rpc31 PF11705.6 MSTRG.76289.1_1 - 0.16 12.0 16.7 0.21 11.7 16.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FixO PF02433.13 MSTRG.76289.1_1 - 0.18 11.1 3.6 0.22 10.8 3.6 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO BPL_N PF09825.7 MSTRG.76289.1_1 - 0.26 10.2 3.7 0.31 9.9 3.7 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FAM60A PF15396.4 MSTRG.76289.1_1 - 0.51 10.2 8.7 0.62 9.9 8.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A GAGA_bind PF06217.10 MSTRG.76289.1_1 - 0.53 10.4 8.7 0.57 10.3 8.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family OSTMP1 PF09777.7 MSTRG.78553.1_2 - 5.3e-81 271.4 7.9 7.6e-81 270.9 7.9 1.2 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.4 MSTRG.78553.1_2 - 0.0027 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 CECR6/TMEM121 family Pep_M12B_propep PF01562.17 MSTRG.12809.1_2 - 2.2e-30 105.6 0.6 3.6e-30 104.9 0.6 1.2 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.17 MSTRG.12809.1_2 - 1.5e-22 80.3 0.0 2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.4 MSTRG.12809.1_2 - 5.4e-05 23.3 0.0 8.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.4 MSTRG.12809.1_2 - 0.054 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like VERL PF11386.6 MSTRG.93994.1_1 - 0.078 13.0 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin zf-H2C2_2 PF13465.4 MSTRG.98143.1_3 - 3e-07 30.5 0.5 3e-07 30.5 0.5 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.98143.1_3 - 5.4e-07 29.6 12.7 0.0002 21.5 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.98143.1_3 - 0.001 19.5 12.9 0.0091 16.6 3.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger OTT_1508_deam PF14441.4 MSTRG.98143.1_3 - 0.046 13.5 3.5 0.11 12.3 3.5 1.8 1 1 0 1 1 1 0 OTT_1508-like deaminase zf-C2HE PF16278.3 MSTRG.98143.1_3 - 0.64 10.4 7.9 3.5 8.0 7.9 2.1 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.3 MSTRG.98143.1_3 - 1.4 8.7 10.0 9.3 6.0 0.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.5 MSTRG.98143.1_3 - 1.4 9.2 11.4 1.6 9.1 2.4 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Filament PF00038.19 MSTRG.92242.1_3 - 4.5e-80 269.4 19.8 5.1e-80 269.2 19.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.12 MSTRG.92242.1_3 - 6.1e-05 22.8 15.0 6.1e-05 22.8 15.0 2.1 1 1 1 2 2 2 1 IncA protein TPR_MLP1_2 PF07926.10 MSTRG.92242.1_3 - 0.0048 16.8 20.3 0.3 11.0 12.9 3.8 1 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein TBPIP PF07106.11 MSTRG.92242.1_3 - 0.0067 16.1 7.5 0.0067 16.1 7.5 2.6 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.10 MSTRG.92242.1_3 - 0.008 15.5 7.3 0.022 14.1 3.4 2.1 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.10 MSTRG.92242.1_3 - 0.012 15.5 3.9 0.012 15.5 3.9 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.4 MSTRG.92242.1_3 - 0.019 14.2 11.0 0.0088 15.3 7.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.13 MSTRG.92242.1_3 - 0.025 14.2 13.4 0.31 10.7 0.7 3.7 3 1 0 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.6 MSTRG.92242.1_3 - 0.032 14.1 1.7 0.032 14.1 1.7 3.9 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF2461 PF09365.8 MSTRG.92242.1_3 - 0.033 14.0 1.2 0.96 9.2 0.1 2.7 2 1 1 3 3 3 0 Conserved hypothetical protein (DUF2461) Lectin_N PF03954.12 MSTRG.92242.1_3 - 0.063 12.9 7.9 0.28 10.8 0.4 2.7 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain OEP PF02321.16 MSTRG.92242.1_3 - 0.17 11.6 7.5 0.17 11.6 6.0 1.7 1 1 0 1 1 1 0 Outer membrane efflux protein CCDC92 PF14916.4 MSTRG.92242.1_3 - 0.19 11.4 6.4 1.2 8.8 0.3 3.5 3 1 0 3 3 3 0 Coiled-coil domain of unknown function Spc7 PF08317.9 MSTRG.92242.1_3 - 0.23 10.2 21.4 0.56 8.9 6.8 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Vps51 PF08700.9 MSTRG.92242.1_3 - 0.31 11.0 9.4 0.56 10.2 1.0 3.3 3 0 0 3 3 3 0 Vps51/Vps67 DUF489 PF04356.10 MSTRG.92242.1_3 - 0.32 10.8 8.5 0.14 12.1 5.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Bacillus_HBL PF05791.9 MSTRG.92242.1_3 - 0.36 10.4 8.3 0.15 11.7 4.4 2.3 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.8 MSTRG.92242.1_3 - 0.49 10.5 19.0 0.5 10.4 6.3 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family UPF0449 PF15136.4 MSTRG.92242.1_3 - 0.55 10.6 10.9 0.072 13.4 2.4 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Jnk-SapK_ap_N PF09744.7 MSTRG.92242.1_3 - 0.66 10.1 17.9 0.13 12.4 7.5 2.7 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF1759 PF03564.13 MSTRG.92242.1_3 - 0.66 9.8 8.6 0.31 10.8 0.5 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1759) ATG16 PF08614.9 MSTRG.92242.1_3 - 0.99 9.4 20.8 1.5 8.8 1.0 2.9 1 1 0 3 3 3 0 Autophagy protein 16 (ATG16) BRE1 PF08647.9 MSTRG.92242.1_3 - 1.2 9.2 17.0 0.1 12.6 1.2 3.5 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Prefoldin_2 PF01920.18 MSTRG.92242.1_3 - 1.6 8.6 16.1 0.63 9.9 1.0 3.7 2 1 1 3 3 3 0 Prefoldin subunit DUF1664 PF07889.10 MSTRG.92242.1_3 - 1.8 8.4 15.4 1.8 8.4 1.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF641 PF04859.10 MSTRG.92242.1_3 - 2.5 8.3 16.3 2.3 8.5 0.3 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF5082 PF16888.3 MSTRG.92242.1_3 - 2.6 8.3 17.1 1.4 9.2 1.9 3.6 2 2 0 3 3 3 0 Domain of unknown function (DUF5082) Laminin_II PF06009.10 MSTRG.92242.1_3 - 2.9 7.8 15.3 13 5.6 0.9 3.3 2 2 1 3 3 3 0 Laminin Domain II Tektin PF03148.12 MSTRG.92242.1_3 - 3.1 6.3 21.8 2.2 6.8 16.6 2.3 2 1 0 2 2 2 0 Tektin family V_ATPase_I PF01496.17 MSTRG.92242.1_3 - 3.4 5.3 15.0 0.17 9.6 3.7 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.7 MSTRG.92242.1_3 - 3.7 6.4 10.8 0.82 8.6 3.6 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Kinetocho_Slk19 PF12709.5 MSTRG.92242.1_3 - 4.7 7.6 17.8 7.6 6.9 4.9 4.0 2 1 2 4 4 4 0 Central kinetochore-associated DUF4094 PF13334.4 MSTRG.92242.1_3 - 5.5 7.3 7.1 4.2 7.7 1.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) HIP1_clath_bdg PF16515.3 MSTRG.92242.1_3 - 6.5 7.3 22.4 10 6.7 6.5 3.4 1 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Bap31 PF05529.10 MSTRG.92242.1_3 - 7.8 5.9 15.6 94 2.4 9.4 3.2 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like RTP1_C2 PF10304.7 MSTRG.27921.1_3 - 3.5e-13 48.8 5.0 5.3e-13 48.2 5.0 1.3 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Sugar_tr PF00083.22 MSTRG.131222.1_2 - 5.5e-156 519.8 25.8 5.5e-156 519.8 25.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.14 MSTRG.131222.1_2 - 2.3e-13 49.7 38.1 1.8e-12 46.7 34.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily IF4E PF01652.16 MSTRG.117178.2_3 - 3.6e-35 121.0 2.4 4.5e-35 120.6 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RVT_1 PF00078.25 MSTRG.72050.1_2 - 1.9e-05 24.2 0.1 2.1e-05 24.0 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.11 MSTRG.9279.1_1 - 8.4 6.1 25.2 11 5.7 25.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ART PF01129.16 MSTRG.38978.1_2 - 0.0029 16.8 0.0 0.0039 16.4 0.0 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase HisG_C PF08029.9 MSTRG.31744.1_3 - 0.0023 17.9 0.0 0.0034 17.4 0.0 1.2 1 0 0 1 1 1 1 HisG, C-terminal domain Med23 PF11573.6 MSTRG.17558.1_3 - 1.5e-15 56.0 0.1 1.9e-15 55.6 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 RNase_H2-Ydr279 PF09468.8 MSTRG.55769.1_2 - 4.6e-09 36.1 0.1 5.3e-09 35.9 0.1 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) CXCXC PF03128.12 MSTRG.118201.1_2 - 0.3 11.5 4.4 0.51 10.8 3.2 2.1 2 0 0 2 2 2 0 CXCXC repeat SecIII_SopE_N PF05364.12 MSTRG.73318.1_2 - 0.17 11.9 2.6 0.39 10.7 2.6 1.7 1 1 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus Toxin_12 PF07740.10 MSTRG.96592.1_2 - 0.015 15.8 1.6 0.023 15.2 1.6 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin DUF3723 PF12520.6 MSTRG.78214.1_3 - 0.015 13.8 0.3 0.022 13.4 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3723) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.78214.1_3 - 0.018 15.1 0.3 0.032 14.3 0.2 1.5 1 1 0 1 1 1 0 Transposase HTH_38 PF13936.4 MSTRG.104718.1_3 - 0.077 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain C1_1 PF00130.20 MSTRG.120511.2_1 - 2.3e-06 27.2 9.0 2.3e-06 27.2 9.0 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.21 MSTRG.120511.2_1 - 8.7e-05 22.6 1.7 0.00024 21.2 1.7 1.9 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain HDV_ag PF01517.16 MSTRG.120511.2_1 - 0.028 14.1 2.4 0.062 13.0 2.4 1.6 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Bul1_C PF04426.10 MSTRG.120511.2_1 - 0.49 9.6 5.1 0.57 9.4 3.6 1.8 1 1 0 1 1 1 0 Bul1 C terminus LMBR1 PF04791.14 MSTRG.120511.2_1 - 3.7 6.2 7.5 5.2 5.7 7.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IL8 PF00048.18 MSTRG.28938.1_1 - 2.2e-12 46.8 0.2 3.7e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DDE_3 PF13358.4 MSTRG.35549.1_2 - 3e-11 43.2 0.2 3.6e-11 42.9 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.4 MSTRG.26012.1_2 - 0.041 14.4 0.4 0.08 13.4 0.2 1.5 2 0 0 2 2 2 0 Homeodomain-like domain Cyclin_N PF00134.21 MSTRG.77046.1_2 - 4.5e-08 32.8 0.0 6.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain P53_tetramer PF07710.9 MSTRG.4555.1_2 - 7.8e-17 60.2 0.3 4.9e-16 57.6 0.1 2.1 2 0 0 2 2 2 1 P53 tetramerisation motif P53 PF00870.16 MSTRG.4555.1_2 - 7.1e-12 45.3 2.7 8.4e-12 45.0 1.5 1.7 2 0 0 2 2 2 1 P53 DNA-binding domain TFIIE-A_C PF11521.6 MSTRG.4555.1_2 - 0.0012 19.0 0.1 0.0019 18.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha Ras PF00071.20 MSTRG.24548.1_2 - 5.1e-08 32.5 0.1 6.2e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 MSTRG.24548.1_2 - 0.0034 17.5 0.1 0.0043 17.1 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gemini_AL3 PF01407.15 MSTRG.63432.1_1 - 0.029 14.1 0.2 0.035 13.8 0.2 1.1 1 0 0 1 1 1 0 Geminivirus AL3 protein DUF3441 PF11923.6 MSTRG.2391.1_1 - 5e-26 90.8 0.1 5e-26 90.8 0.1 2.8 1 1 2 3 3 3 1 Domain of unknown function (DUF3441) Herpes_PAP PF03325.11 MSTRG.2391.1_1 - 0.25 10.3 2.4 0.35 9.8 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein 60KD_IMP PF02096.18 MSTRG.2391.1_1 - 0.33 10.7 1.5 0.54 10.0 1.5 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein MIF4G_like_2 PF09090.9 MSTRG.2391.1_1 - 0.36 10.1 3.5 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 MIF4G like IMPDH PF00478.23 MSTRG.140566.1_2 - 3.3e-49 167.6 0.9 3.7e-49 167.4 0.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.13 MSTRG.140566.1_2 - 2.1e-07 30.5 0.4 3e-07 30.0 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.16 MSTRG.140566.1_2 - 8.8e-07 28.1 0.3 1.4e-06 27.4 0.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.12 MSTRG.140566.1_2 - 0.00041 19.6 0.2 0.00057 19.1 0.2 1.1 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.19 MSTRG.140566.1_2 - 0.0007 19.0 0.0 0.0014 18.0 0.0 1.5 2 0 0 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.15 MSTRG.140566.1_2 - 0.0072 15.4 0.4 0.014 14.5 0.4 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase TIG PF01833.22 MSTRG.14527.1_3 - 4.6e-08 32.9 0.8 0.00033 20.5 0.0 2.1 2 0 0 2 2 2 2 IPT/TIG domain Phage_holin_2_3 PF16080.3 MSTRG.14527.1_3 - 0.013 15.1 0.1 0.029 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin family HP1 DUF2418 PF10332.7 MSTRG.70666.1_3 - 0.38 11.2 4.3 0.68 10.4 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) Toxin_32 PF08120.9 MSTRG.144280.1_1 - 0.016 14.9 2.5 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Tamulustoxin family AIG1 PF04548.14 MSTRG.144280.1_2 - 4.1e-54 183.0 6.8 1.6e-42 145.1 1.1 2.0 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.21 MSTRG.144280.1_2 - 1.1e-12 47.9 2.7 3.1e-08 33.6 0.1 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.16 MSTRG.144280.1_2 - 0.00077 18.9 0.7 0.062 12.7 0.3 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.14 MSTRG.144280.1_2 - 0.0016 18.3 6.6 0.12 12.1 0.6 3.5 1 1 2 3 3 3 2 Protein of unknown function, DUF258 Septin PF00735.16 MSTRG.144280.1_2 - 0.0044 16.1 3.4 0.17 11.0 0.5 2.7 2 1 1 3 3 3 2 Septin BrnT_toxin PF04365.11 MSTRG.144280.1_2 - 0.027 14.7 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system Ras PF00071.20 MSTRG.144280.1_2 - 0.054 12.9 2.8 5.2 6.5 0.4 2.8 2 1 1 3 3 3 0 Ras family Dynamin_N PF00350.21 MSTRG.144280.1_2 - 0.12 12.3 4.3 2.9 7.8 0.3 2.6 2 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.25 MSTRG.144280.1_2 - 0.15 12.4 1.9 15 6.0 0.3 2.6 2 1 0 2 2 2 0 ABC transporter Roc PF08477.11 MSTRG.144280.1_2 - 0.2 11.7 2.8 5.3 7.2 0.2 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CPSF_A PF03178.13 MSTRG.104268.1_1 - 3.2e-37 128.4 0.0 3.5e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region GRAS PF03514.12 MSTRG.9743.1_3 - 0.0073 15.2 0.0 0.0083 15.0 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family TMEM210 PF15195.4 MSTRG.9743.1_3 - 0.035 14.4 0.0 0.043 14.1 0.0 1.1 1 0 0 1 1 1 0 TMEM210 family GcrA PF07750.9 MSTRG.9743.1_3 - 0.14 12.4 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 GcrA cell cycle regulator DUF2644 PF10841.6 MSTRG.65772.1_2 - 0.76 9.9 0.1 0.76 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) CAS_CSE1 PF03378.13 MSTRG.51071.1_2 - 1.8e-32 112.3 0.0 2e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus DUF4633 PF15464.4 MSTRG.30528.1_2 - 0.014 15.4 2.5 0.019 15.0 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) YfhO PF09586.8 MSTRG.30528.1_2 - 0.044 11.9 0.4 0.046 11.8 0.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO PADR1 PF08063.10 MSTRG.86429.1_2 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain PHR PF08005.10 MSTRG.48691.1_1 - 5.9e-54 182.7 1.7 9.4e-54 182.0 1.7 1.3 1 0 0 1 1 1 1 PHR domain BTB PF00651.29 MSTRG.48691.1_1 - 1.4e-28 99.2 0.1 7.2e-27 93.7 0.0 2.7 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.13 MSTRG.48691.1_1 - 1.3e-08 34.7 0.2 2e-07 30.9 0.0 2.8 1 1 1 2 2 2 1 BTB And C-terminal Kelch Glyco_hydro_114 PF03537.11 MSTRG.48691.1_1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 AIG1 PF04548.14 MSTRG.55191.1_2 - 1.9e-57 193.9 0.0 1.3e-39 135.6 0.0 2.2 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.21 MSTRG.55191.1_2 - 0.00027 20.9 0.0 0.001 19.0 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF2188 PF09954.7 MSTRG.55191.1_2 - 0.073 13.1 0.1 0.31 11.1 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF2719 PF10891.6 MSTRG.55191.1_2 - 0.14 12.0 0.0 0.96 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2719) PSI_integrin PF17205.1 MSTRG.7573.1_3 - 0.21 11.3 0.1 0.21 11.3 0.1 2.9 2 1 1 3 3 3 0 Integrin plexin domain DUF4071 PF13281.4 MSTRG.46231.1_2 - 8.3e-19 67.8 0.2 1.1e-18 67.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) DUF678 PF05077.10 MSTRG.46231.1_2 - 3.6 7.6 9.2 0.14 12.1 1.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF678) DUF2368 PF10166.7 MSTRG.15275.2_1 - 3e-19 68.9 11.0 3.3e-19 68.7 11.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) DUF3591 PF12157.6 MSTRG.116289.1_3 - 1e-23 83.6 0.0 1.1e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) DDE_3 PF13358.4 MSTRG.107003.1_1 - 6.4e-09 35.6 0.0 6.5e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease GETHR PF05671.9 MSTRG.102138.1_1 - 0.041 13.1 0.7 0.06 12.6 0.7 1.2 1 0 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) WH2 PF02205.18 MSTRG.3400.1_1 - 3.6e-05 23.3 2.2 0.00071 19.2 0.1 2.8 3 0 0 3 3 3 2 WH2 motif DUF2358 PF10184.7 MSTRG.120852.1_1 - 1.9e-27 95.6 0.2 3.1e-27 95.0 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) C2 PF00168.28 MSTRG.45812.1_2 - 0.0012 19.0 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 C2 domain DUF4816 PF16086.3 MSTRG.15527.1_1 - 0.01 15.7 28.1 0.019 14.8 20.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4816) 5TM-5TMR_LYT PF07694.10 MSTRG.15527.1_2 - 0.068 12.5 7.7 0.1 11.9 7.7 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF2798 PF11391.6 MSTRG.15527.1_2 - 1.3 9.0 12.5 35 4.4 12.5 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) Thia_YuaJ PF09515.8 MSTRG.15527.1_2 - 1.9 8.3 6.7 2.9 7.8 0.9 2.4 1 1 1 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) DUF2953 PF11167.6 MSTRG.15527.1_2 - 6.6 6.8 6.1 5.1e+02 0.7 6.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2953) VIT1 PF01988.17 MSTRG.15527.1_3 - 0.058 13.1 2.9 0.064 13.0 2.9 1.1 1 0 0 1 1 1 0 VIT family zf-MIZ PF02891.18 MSTRG.58076.1_3 - 0.025 14.2 2.0 0.39 10.4 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger MRI PF15325.4 MSTRG.120741.1_2 - 0.26 12.4 1.2 0.49 11.5 1.2 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection DNA_pol_E_B PF04042.14 MSTRG.42363.1_3 - 2.3e-18 66.2 0.0 2.5e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Rft-1 PF04506.11 MSTRG.138144.1_2 - 0.015 14.0 0.2 0.017 13.8 0.2 1.0 1 0 0 1 1 1 0 Rft protein Alg14 PF08660.9 MSTRG.138144.1_2 - 0.14 11.9 3.7 0.21 11.4 3.7 1.3 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like HemY_N PF07219.11 MSTRG.138144.1_2 - 1 9.4 2.5 0.75 9.9 0.7 1.7 1 1 1 2 2 2 0 HemY protein N-terminus PLU-1 PF08429.9 MSTRG.103393.1_3 - 1.2e-12 47.6 0.0 1.4e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 PLU-1-like protein Cadherin PF00028.15 MSTRG.136138.1_2 - 7.3e-08 32.6 0.0 8.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Cadherin domain DUF3370 PF11850.6 MSTRG.136138.1_2 - 0.068 11.9 0.0 0.076 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) HTH_38 PF13936.4 MSTRG.43010.1_2 - 0.00039 20.0 0.1 0.00057 19.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.43010.1_2 - 0.0034 17.0 0.1 0.0052 16.4 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.4 MSTRG.43010.1_2 - 0.11 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 PAX PF00292.16 MSTRG.43010.1_2 - 0.11 12.2 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain Malectin PF11721.6 MSTRG.96047.1_3 - 3.3e-42 144.3 0.0 4.1e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Di-glucose binding within endoplasmic reticulum HHH_8 PF14716.4 MSTRG.1602.1_2 - 0.028 14.6 0.1 9.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain FAA_hydrolase_N PF09298.9 MSTRG.41638.2_1 - 0.053 13.7 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal FAA_hydrolase_N PF09298.9 MSTRG.41638.2_2 - 4.8e-20 71.6 0.0 6.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HEV_ORF1 PF02444.14 MSTRG.41638.2_2 - 0.039 14.4 0.0 0.054 13.9 0.0 1.2 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) FH2 PF02181.21 MSTRG.57903.1_2 - 5.2e-18 65.2 0.8 5.6e-18 65.1 0.8 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain CLU PF13236.4 MSTRG.23988.1_1 - 1.2e-13 51.3 0.0 2.7e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.5 MSTRG.23988.1_1 - 2.7e-08 33.9 0.0 5.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Exo_endo_phos_2 PF14529.4 MSTRG.127122.1_1 - 0.021 14.6 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF2674 PF10879.6 MSTRG.21056.1_1 - 0.86 9.4 3.3 16 5.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) DUF1664 PF07889.10 MSTRG.21056.1_1 - 0.94 9.4 2.8 6.4 6.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Hep_core_N PF08290.9 MSTRG.137170.1_3 - 0.063 13.1 0.2 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger RVT_1 PF00078.25 MSTRG.2061.1_1 - 1.9e-05 24.2 0.0 2.1e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.23 MSTRG.33955.1_2 - 1.4e-22 80.2 0.1 1.8e-22 79.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.33955.1_2 - 1e-11 44.5 0.1 1.2e-11 44.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.25 MSTRG.123581.1_1 - 3.1e-11 43.1 0.1 3.5e-11 42.9 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EFG_C PF00679.22 MSTRG.102926.1_1 - 3.5e-24 84.5 0.0 5.4e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.16 MSTRG.102926.1_1 - 6e-07 29.1 0.1 2.3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV DUF4395 PF14340.4 MSTRG.143907.1_1 - 0.065 13.4 2.1 0.083 13.1 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) LRRCT PF01463.22 MSTRG.120657.1_3 - 0.07 13.6 1.0 77 4.1 0.0 4.3 3 2 2 5 5 5 0 Leucine rich repeat C-terminal domain DUF346 PF03984.11 MSTRG.120657.1_3 - 0.089 12.4 0.0 14 5.4 0.0 2.8 2 1 0 2 2 2 0 Repeat of unknown function (DUF346) CdCA1 PF10563.7 MSTRG.120657.1_3 - 0.093 12.3 0.0 4.6 6.8 0.0 2.1 1 1 1 2 2 2 0 Cadmium carbonic anhydrase repeat ABC_tran PF00005.25 MSTRG.109535.1_3 - 0.0036 17.7 0.0 0.005 17.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Toxin_ToxA PF11584.6 MSTRG.124446.1_2 - 0.016 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA zf-C2HC PF01530.16 MSTRG.90174.1_1 - 0.0041 17.2 0.0 1.5e+02 2.5 0.0 4.7 1 1 4 5 5 5 0 Zinc finger, C2HC type DUF4734 PF15881.3 MSTRG.90174.1_1 - 0.29 11.2 9.2 17 5.5 0.5 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4734) TMEM40 PF15817.3 MSTRG.90174.1_1 - 3.2 7.4 6.4 8.6 6.0 1.1 2.1 1 1 1 2 2 2 0 Transmembrane protein 40 family DUF1891 PF09004.8 MSTRG.67725.1_2 - 0.0049 16.3 0.7 0.013 14.9 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) UPF0547 PF10571.7 MSTRG.109317.1_1 - 7.6e-12 45.0 9.0 1.3e-11 44.2 9.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zinc_ribbon_16 PF17034.3 MSTRG.109317.1_1 - 0.0016 18.5 1.0 0.0022 18.1 1.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon like family Exo_endo_phos_2 PF14529.4 MSTRG.71350.1_3 - 0.0017 18.1 0.0 0.0031 17.2 0.0 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.21 MSTRG.71350.1_3 - 0.01 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Caldesmon PF02029.13 MSTRG.123109.1_2 - 8.3e-27 94.0 38.5 8.8e-27 93.9 38.5 1.0 1 0 0 1 1 1 1 Caldesmon Cytomega_UL84 PF06284.9 MSTRG.123109.1_2 - 2.2 6.5 8.9 4.1 5.6 8.9 1.5 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RNA_pol_Rpb8 PF03870.13 MSTRG.30792.1_3 - 6.7e-25 87.8 0.0 7.2e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.3 MSTRG.30792.1_3 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase, subunit G Mistic PF11458.6 MSTRG.93516.1_3 - 0.074 13.4 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 Membrane-integrating protein Mistic Clathrin_H_link PF13838.4 MSTRG.2467.1_1 - 2.7e-20 71.9 0.1 3.9e-20 71.4 0.1 1.3 1 0 0 1 1 1 1 Clathrin-H-link STPPase_N PF16891.3 MSTRG.91830.1_1 - 0.0001 22.6 0.4 0.00018 21.7 0.4 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain FISNA PF14484.4 MSTRG.81627.1_2 - 7.1e-28 96.5 1.8 1.6e-27 95.4 1.8 1.6 1 0 0 1 1 1 1 Fish-specific NACHT associated domain PYRIN PF02758.14 MSTRG.81627.1_2 - 3.4e-10 39.8 0.2 3.4e-10 39.8 0.2 1.9 2 0 0 2 2 2 1 PAAD/DAPIN/Pyrin domain NACHT PF05729.10 MSTRG.81627.1_2 - 4.8e-09 36.2 0.1 4.6e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain DUF5029 PF16432.3 MSTRG.81627.1_2 - 0.03 13.7 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) DEAD PF00270.27 MSTRG.81627.1_2 - 0.035 13.7 0.1 0.55 9.8 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase UPF0561 PF10573.7 MSTRG.81627.1_2 - 0.11 12.5 0.2 0.3 11.1 0.1 1.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0561 HTH_38 PF13936.4 MSTRG.79778.1_2 - 1.8e-05 24.3 0.1 2.2e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.79778.1_2 - 6.4e-05 22.5 0.1 9.8e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Ribosomal_S13_N PF08069.10 MSTRG.79778.1_2 - 0.004 17.0 0.3 0.062 13.2 0.1 2.1 1 1 1 2 2 2 1 Ribosomal S13/S15 N-terminal domain HTH_Tnp_ISL3 PF13542.4 MSTRG.79778.1_2 - 0.035 13.4 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 PAX PF00292.16 MSTRG.79778.1_2 - 0.11 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain DUF4269 PF14091.4 MSTRG.79778.1_2 - 0.11 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) YkuD PF03734.12 MSTRG.40604.1_3 - 0.16 12.2 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Rap_GAP PF02145.13 MSTRG.32215.1_2 - 2.3e-25 89.1 0.0 2.4e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Rap/ran-GAP RWD PF05773.20 MSTRG.65317.1_1 - 0.00085 19.5 0.5 0.0011 19.2 0.5 1.2 1 0 0 1 1 1 1 RWD domain HCO3_cotransp PF00955.19 MSTRG.65317.1_1 - 0.0021 16.9 0.3 0.0039 16.0 0.3 1.4 1 0 0 1 1 1 1 HCO3- transporter family DUF4181 PF13789.4 MSTRG.65317.1_1 - 0.041 14.0 0.5 0.041 14.0 0.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.141707.1_1 - 0.0012 18.9 0.7 0.0016 18.5 0.7 1.2 1 0 0 1 1 1 1 Transposase RRM_1 PF00076.20 MSTRG.143593.2_3 - 1.3e-13 50.4 0.0 2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.9 MSTRG.143593.2_3 - 0.07 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Corona_nucleoca PF00937.16 MSTRG.143593.2_3 - 0.11 11.3 5.5 0.15 10.9 5.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PRP38_assoc PF12871.5 MSTRG.143593.2_3 - 0.58 10.6 23.4 0.93 10.0 23.4 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term IRF PF00605.15 MSTRG.129609.1_3 - 4e-28 97.6 0.2 4e-28 97.6 0.2 1.8 2 0 0 2 2 2 1 Interferon regulatory factor transcription factor Ank_2 PF12796.5 MSTRG.41374.1_1 - 2e-23 82.6 3.5 1.6e-15 57.3 0.6 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.4 MSTRG.41374.1_1 - 1.1e-20 73.6 1.3 4.4e-12 46.1 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 MSTRG.41374.1_1 - 8.3e-14 50.2 0.7 0.0008 19.5 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.4 MSTRG.41374.1_1 - 1.7e-12 47.2 2.8 1.7e-08 34.4 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.28 MSTRG.41374.1_1 - 1.2e-11 44.4 5.6 0.00065 19.9 0.1 4.1 4 1 0 4 4 4 3 Ankyrin repeat DUF3447 PF11929.6 MSTRG.41374.1_1 - 0.056 13.3 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) DDE_3 PF13358.4 MSTRG.27840.1_1 - 3e-08 33.4 0.4 3.9e-08 33.0 0.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease EGF_2 PF07974.11 MSTRG.106200.1_3 - 0.00038 20.6 10.2 0.00038 20.6 10.2 2.2 2 0 0 2 2 2 2 EGF-like domain BRCA2 PF00634.16 MSTRG.68110.1_2 - 0.046 13.1 0.2 0.067 12.5 0.2 1.2 1 0 0 1 1 1 0 BRCA2 repeat RsfS PF02410.13 MSTRG.85702.1_1 - 9.3e-09 35.5 0.1 1.1e-07 32.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation DENN PF02141.19 MSTRG.85702.1_1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 DENN (AEX-3) domain zf-A20 PF01754.14 MSTRG.62834.1_1 - 0.036 13.9 0.6 0.073 12.9 0.6 1.6 1 0 0 1 1 1 0 A20-like zinc finger C1-set PF07654.13 MSTRG.62834.1_2 - 1.3e-09 38.3 1.5 8.8e-08 32.4 0.3 2.1 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Ig_3 PF13927.4 MSTRG.62834.1_2 - 0.00039 20.9 2.0 0.13 12.8 0.2 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 MSTRG.62834.1_2 - 0.027 14.4 0.7 0.12 12.4 0.2 2.0 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain ig PF00047.23 MSTRG.62834.1_2 - 0.077 13.0 2.0 0.33 11.0 0.5 2.1 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.14 MSTRG.62834.1_2 - 0.083 12.8 0.7 1.7 8.6 0.1 2.1 2 0 0 2 2 2 0 Immunoglobulin I-set domain TRC8_N PF13705.4 MSTRG.41092.1_1 - 2.2e-07 30.0 3.2 2.4e-07 29.9 3.2 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain DUF2628 PF10947.6 MSTRG.41092.1_1 - 2.1 8.6 6.2 2.8 8.2 6.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Herpes_LMP1 PF05297.9 MSTRG.41092.1_1 - 5.5 5.9 6.6 5.6 5.9 6.6 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Thioredoxin_6 PF13848.4 MSTRG.43368.1_3 - 2.5e-09 37.3 0.0 3.1e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain WW PF00397.24 MSTRG.90830.1_3 - 2.4e-28 97.6 11.4 1.5e-09 37.5 0.2 3.3 3 0 0 3 3 3 3 WW domain POPLD PF08170.10 MSTRG.11413.1_3 - 0.4 10.9 2.7 0.57 10.5 2.7 1.3 1 1 0 1 1 1 0 POPLD (NUC188) domain Neur_chan_memb PF02932.14 MSTRG.11413.1_3 - 0.76 9.6 2.3 0.76 9.6 2.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Clat_adaptor_s PF01217.18 MSTRG.54596.1_3 - 2.2e-52 176.7 3.5 2.9e-52 176.3 3.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PsbJ PF01788.15 MSTRG.97212.1_3 - 0.17 11.7 6.7 9.1 6.1 0.1 4.0 4 0 0 4 4 4 0 PsbJ TPT PF03151.14 MSTRG.49471.1_3 - 7.6e-20 71.3 11.5 9.5e-20 71.0 11.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.18 MSTRG.49471.1_3 - 1.9e-06 28.0 22.1 0.0036 17.3 6.0 2.4 2 1 0 2 2 2 2 EamA-like transporter family PH PF00169.27 MSTRG.131974.2_3 - 1e-08 35.5 0.7 2.4e-08 34.3 0.7 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.4 MSTRG.131974.2_3 - 7.9e-05 22.7 0.6 0.00018 21.6 0.6 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.4 MSTRG.131974.2_3 - 0.017 15.4 1.5 0.017 15.4 1.5 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain Tox-GHH PF15636.4 MSTRG.134080.1_1 - 0.089 12.6 1.2 0.12 12.2 1.2 1.2 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin ArfGap PF01412.16 MSTRG.80345.1_2 - 1.3e-33 115.4 0.0 1.4e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RVT_1 PF00078.25 MSTRG.92209.1_2 - 0.00053 19.4 0.0 0.00058 19.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.4 MSTRG.52060.1_2 - 3.5e-06 26.7 0.0 5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.24 MSTRG.52060.1_2 - 0.0091 16.1 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Arfaptin PF06456.11 MSTRG.50777.1_1 - 3.9e-23 82.1 0.4 5.4e-23 81.6 0.4 1.2 1 0 0 1 1 1 1 Arfaptin-like domain DUF3963 PF13124.4 MSTRG.100557.1_1 - 0.031 14.1 1.0 0.068 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) P33MONOX PF15302.4 MSTRG.47695.1_1 - 2.2e-64 217.9 10.0 3.7e-62 210.5 10.0 2.0 1 1 0 1 1 1 1 P33 mono-oxygenase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.60378.1_1 - 3.3e-06 27.1 0.2 4.5e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Transposase Fibrinogen_C PF00147.16 MSTRG.45595.1_1 - 4e-49 167.3 3.6 5.2e-49 166.9 3.6 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF2570 PF10828.6 MSTRG.45595.1_1 - 0.031 14.0 1.1 0.052 13.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Spc7 PF08317.9 MSTRG.45595.1_1 - 0.042 12.6 0.5 0.055 12.2 0.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1216 PF06746.9 MSTRG.45595.1_1 - 0.049 13.5 0.2 0.13 12.2 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) zf-Tim10_DDP PF02953.13 MSTRG.45595.1_1 - 0.14 11.7 0.3 0.14 11.7 0.3 1.9 2 0 0 2 2 2 0 Tim10/DDP family zinc finger CENP-H PF05837.10 MSTRG.45595.1_1 - 0.18 12.1 1.1 0.4 11.0 1.1 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) VGLL4 PF15245.4 MSTRG.107441.1_1 - 1.3e-12 48.1 0.1 1.6e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Transcription cofactor vestigial-like protein 4 MIT PF04212.16 MSTRG.47856.2_3 - 2.2e-05 24.3 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Sel1 PF08238.10 MSTRG.47856.2_3 - 0.049 14.2 0.4 0.76 10.4 0.1 2.1 1 1 1 2 2 2 0 Sel1 repeat HUN PF08729.8 MSTRG.74829.1_1 - 2.4e-10 40.1 3.1 1.2e-08 34.7 1.1 2.2 2 0 0 2 2 2 2 HPC2 and ubinuclein domain DDE_3 PF13358.4 MSTRG.42903.1_2 - 1.7e-09 37.4 0.3 2.6e-09 36.9 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FixS PF03597.13 MSTRG.82937.1_1 - 0.27 10.8 1.5 0.45 10.1 1.5 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Prenyltrans PF00432.19 MSTRG.72304.1_2 - 0.095 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat eIF-5_eIF-2B PF01873.15 MSTRG.5480.4_3 - 5.6e-41 139.0 0.6 1.7e-40 137.4 0.1 2.0 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.16 MSTRG.5480.4_3 - 2.2e-21 75.7 1.2 2.2e-21 75.7 1.2 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Exonuc_VII_L PF02601.13 MSTRG.107962.1_2 - 0.38 10.1 9.6 0.52 9.7 9.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.12 MSTRG.107962.1_2 - 1.3 8.6 16.6 2.2 7.9 16.6 1.3 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.7 MSTRG.107962.1_2 - 5.5 5.8 21.4 8.8 5.2 21.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF659 PF04937.13 MSTRG.24642.1_1 - 5.7e-10 39.1 0.0 7.9e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DDE_3 PF13358.4 MSTRG.98979.1_2 - 0.0024 17.5 0.1 0.003 17.2 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RanBP PF00641.16 MSTRG.87772.1_1 - 7e-08 31.5 2.3 1.3e-07 30.6 2.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Prion_bPrPp PF11587.6 MSTRG.122495.1_2 - 4.3 7.1 8.1 0.22 11.3 2.6 1.7 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal dDENN PF03455.17 MSTRG.132439.1_2 - 7.1e-13 48.2 1.1 1.7e-12 47.0 0.8 1.8 1 1 1 2 2 2 1 dDENN domain Spectrin PF00435.19 MSTRG.44145.1_1 - 5.2e-07 30.0 16.1 0.0028 18.0 2.3 3.0 3 0 0 3 3 3 2 Spectrin repeat CALCOCO1 PF07888.9 MSTRG.44145.1_1 - 0.0011 17.5 9.5 0.0013 17.3 9.5 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Ferritin PF00210.22 MSTRG.44145.1_1 - 0.019 14.8 1.8 1.3 8.8 0.2 2.5 2 1 0 2 2 2 0 Ferritin-like domain DUF1664 PF07889.10 MSTRG.44145.1_1 - 0.071 13.0 6.4 2.2 8.1 0.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SPX PF03105.17 MSTRG.44145.1_1 - 0.11 12.3 11.0 0.17 11.6 11.0 1.3 1 1 0 1 1 1 0 SPX domain ZYG-11_interact PF05884.10 MSTRG.44145.1_1 - 0.3 10.3 1.4 0.66 9.2 0.2 1.8 1 1 1 2 2 2 0 Interactor of ZYG-11 DUF342 PF03961.11 MSTRG.44145.1_1 - 0.67 8.3 9.8 0.96 7.8 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fib_alpha PF08702.8 MSTRG.44145.1_1 - 1.4 9.0 7.5 0.75 9.8 1.1 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Sec34 PF04136.13 MSTRG.44145.1_1 - 3.8 7.3 10.6 0.91 9.3 1.6 2.5 2 1 0 2 2 2 0 Sec34-like family cwf21 PF08312.10 MSTRG.44145.1_1 - 5 7.2 8.7 1.4e+02 2.6 8.7 2.7 1 1 0 1 1 1 0 cwf21 domain PRKG1_interact PF15898.3 MSTRG.44145.1_1 - 7.5 7.4 13.1 14 6.6 1.8 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain PYRIN PF02758.14 MSTRG.62700.1_3 - 2.7e-05 24.1 1.4 0.00032 20.7 1.3 2.2 1 1 0 1 1 1 1 PAAD/DAPIN/Pyrin domain Rootletin PF15035.4 MSTRG.51483.1_2 - 0.0017 18.4 12.9 0.0025 17.8 12.9 1.4 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF972 PF06156.11 MSTRG.51483.1_2 - 0.0024 18.3 5.7 0.0035 17.8 5.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF972) DUF4665 PF15679.3 MSTRG.51483.1_2 - 0.0058 17.1 1.5 0.0078 16.7 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4665) V_ATPase_I PF01496.17 MSTRG.51483.1_2 - 0.0063 14.3 6.7 0.0073 14.1 6.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Taxilin PF09728.7 MSTRG.51483.1_2 - 0.0064 15.7 7.4 0.0064 15.7 7.4 1.7 1 1 1 2 2 2 1 Myosin-like coiled-coil protein NRBF2 PF08961.8 MSTRG.51483.1_2 - 0.011 15.2 4.8 0.011 15.2 4.8 1.8 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.10 MSTRG.51483.1_2 - 0.014 15.7 10.7 0.014 15.7 10.7 1.7 1 1 0 1 1 1 0 Cell division protein ZapB RasGAP_C PF03836.13 MSTRG.51483.1_2 - 0.045 13.8 3.5 0.055 13.5 3.5 1.2 1 0 0 1 1 1 0 RasGAP C-terminus TraF_2 PF13729.4 MSTRG.51483.1_2 - 0.057 12.6 0.1 0.07 12.4 0.1 1.0 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF342 PF03961.11 MSTRG.51483.1_2 - 0.067 11.7 3.6 0.074 11.5 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc7 PF08317.9 MSTRG.51483.1_2 - 0.083 11.6 8.2 0.096 11.4 8.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.3 MSTRG.51483.1_2 - 0.084 13.1 6.0 0.1 12.8 5.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HALZ PF02183.16 MSTRG.51483.1_2 - 0.19 11.9 4.4 0.63 10.2 3.2 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper Phage_cap_E PF03864.13 MSTRG.51483.1_2 - 0.2 10.7 2.7 0.24 10.4 2.7 1.1 1 0 0 1 1 1 0 Phage major capsid protein E PRKG1_interact PF15898.3 MSTRG.51483.1_2 - 0.33 11.8 13.4 0.061 14.1 6.1 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain ERM PF00769.17 MSTRG.51483.1_2 - 0.38 10.4 20.4 0.42 10.3 20.4 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Fmp27_WPPW PF10359.7 MSTRG.51483.1_2 - 0.44 9.2 7.3 0.48 9.1 7.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Prefoldin_2 PF01920.18 MSTRG.51483.1_2 - 0.52 10.2 9.8 0.71 9.7 5.4 2.4 1 1 1 2 2 2 0 Prefoldin subunit GIT_CC PF16559.3 MSTRG.51483.1_2 - 0.57 10.1 6.8 0.43 10.5 0.7 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor APG6 PF04111.10 MSTRG.51483.1_2 - 0.6 9.3 11.7 0.74 9.0 11.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.12 MSTRG.51483.1_2 - 0.72 9.5 13.9 0.96 9.1 13.9 1.3 1 1 0 1 1 1 0 IncA protein DUF1640 PF07798.9 MSTRG.51483.1_2 - 0.78 9.6 9.1 0.78 9.6 7.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF3450 PF11932.6 MSTRG.51483.1_2 - 0.93 8.6 11.8 0.42 9.7 9.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.6 MSTRG.51483.1_2 - 1.1 9.2 14.8 0.31 11.0 10.9 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.9 MSTRG.51483.1_2 - 1.1 9.4 8.4 4.1 7.6 8.2 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.13 MSTRG.51483.1_2 - 4.5 7.0 10.8 7.4 6.3 8.9 2.2 1 1 0 1 1 1 0 Septum formation initiator Atg14 PF10186.7 MSTRG.51483.1_2 - 4.9 6.0 11.5 5.6 5.8 11.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0449 PF15136.4 MSTRG.51483.1_2 - 6 7.3 9.8 6.3 7.2 7.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 TMPIT PF07851.11 MSTRG.51483.1_2 - 7.3 5.6 5.9 8.7 5.3 5.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein CENP-H PF05837.10 MSTRG.51483.1_2 - 7.5 6.9 12.3 11 6.3 12.3 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF2484 PF10658.7 MSTRG.104212.1_1 - 0.019 15.1 0.4 0.031 14.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) HTH_23 PF13384.4 MSTRG.139755.1_3 - 0.00039 20.0 0.0 0.00076 19.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.4 MSTRG.139755.1_3 - 0.00087 18.9 0.5 0.0016 18.1 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.139755.1_3 - 0.0064 16.6 2.1 0.011 15.8 0.1 2.3 2 1 0 2 2 2 1 Transposase HTH_40 PF14493.4 MSTRG.139755.1_3 - 0.017 15.4 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.17 MSTRG.139755.1_3 - 0.059 12.8 0.2 0.15 11.5 0.1 1.7 1 1 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_28 PF13518.4 MSTRG.139755.1_3 - 0.076 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.4 MSTRG.139755.1_3 - 0.12 11.8 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Histone_H2A_C PF16211.3 MSTRG.95937.1_1 - 0.42 10.2 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 C-terminus of histone H2A Crystall PF00030.17 MSTRG.95937.1_2 - 8.8e-22 77.0 0.0 3.2e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin PI3Ka PF00613.18 MSTRG.86977.1_1 - 1e-19 70.5 0.1 1.2e-19 70.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Exo_endo_phos_2 PF14529.4 MSTRG.122245.1_3 - 0.017 14.8 0.0 0.045 13.5 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Tat PF00539.16 MSTRG.121594.1_3 - 0.046 13.8 1.5 0.058 13.4 1.5 1.1 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) HTH_13 PF11972.6 MSTRG.97221.1_1 - 0.077 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 HTH DNA binding domain RVT_1 PF00078.25 MSTRG.2348.1_1 - 0.00015 21.2 0.1 0.00015 21.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.55578.1_1 - 4.1e-07 30.0 0.1 5.2e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Transposase Arg_repressor PF01316.19 MSTRG.55578.1_1 - 0.034 13.8 0.1 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.55578.1_3 - 2.1e-07 30.9 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Transposase HABP4_PAI-RBP1 PF04774.13 MSTRG.38501.1_2 - 8.2e-27 94.2 12.7 1.4e-26 93.5 12.7 1.4 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family HTH_Tnp_Tc3_2 PF01498.16 MSTRG.133914.1_3 - 3.6e-16 59.0 0.7 4.6e-16 58.7 0.7 1.1 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.4 MSTRG.133914.1_3 - 5.6e-06 26.8 1.2 8.5e-06 26.2 1.2 1.3 1 0 0 1 1 1 1 Homeodomain-like domain DUF3521 PF12035.6 MSTRG.41016.1_1 - 0.69 9.8 3.2 12 5.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3521) C2 PF00168.28 MSTRG.64163.1_3 - 2e-14 53.6 0.0 3.2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain CLTH PF10607.7 MSTRG.122972.1_2 - 2.1e-14 53.5 0.7 4.1e-14 52.6 0.7 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Mic1 PF07035.10 MSTRG.122972.1_2 - 0.00051 19.7 0.3 0.0015 18.2 0.0 1.8 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like LisH PF08513.9 MSTRG.122972.1_2 - 0.034 14.0 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 LisH Tubulin PF00091.23 MSTRG.123189.1_2 - 1e-69 234.6 0.0 1.5e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 MSTRG.123189.1_2 - 1.4e-42 144.7 0.1 2.2e-42 144.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 MSTRG.123189.1_2 - 2.1e-05 24.6 0.0 4.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 MSTRG.123189.1_2 - 0.0093 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.4 MSTRG.123189.1_2 - 0.023 13.8 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin like HTH_Tnp_Tc3_1 PF11427.6 MSTRG.138343.1_3 - 0.071 12.8 0.5 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Tc3 transposase Rod_C PF10493.7 MSTRG.96351.1_1 - 0.0091 14.3 0.5 0.01 14.1 0.5 1.0 1 0 0 1 1 1 1 Rough deal protein C-terminal region GAT PF03127.12 MSTRG.69656.1_2 - 6.4e-23 80.7 1.7 7.1e-23 80.6 1.7 1.0 1 0 0 1 1 1 1 GAT domain ToxN_toxin PF13958.4 MSTRG.69656.1_2 - 0.031 14.4 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system EF-G-binding_N PF07299.9 MSTRG.69656.1_2 - 0.085 13.3 0.6 0.15 12.4 0.6 1.5 1 1 0 1 1 1 0 Elongation factor G-binding protein, N-terminal RVT_1 PF00078.25 MSTRG.99128.1_3 - 0.00051 19.5 0.0 0.00059 19.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MGC-24 PF05283.9 MSTRG.112204.1_2 - 9.9 6.5 8.3 1.1 9.6 3.0 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin INCA1 PF15142.4 MSTRG.2946.1_1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 INCA1 Homeobox PF00046.27 MSTRG.4386.1_2 - 2.9e-08 33.3 0.2 4.2e-08 32.7 0.2 1.2 1 0 0 1 1 1 1 Homeobox domain Myosin_head PF00063.19 MSTRG.81229.1_3 - 2e-14 52.6 0.0 2.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.25 MSTRG.81229.1_3 - 5.1e-06 25.7 1.4 1.3e-05 24.4 1.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PriCT_1 PF08708.9 MSTRG.81229.1_3 - 0.14 11.8 0.2 1.1 8.9 0.1 2.3 2 1 1 3 3 3 0 Primase C terminal 1 (PriCT-1) RVT_1 PF00078.25 MSTRG.6750.1_1 - 3.7e-05 23.2 0.0 3.9e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DGC PF08859.9 MSTRG.113389.1_1 - 0.035 14.1 0.2 0.041 13.8 0.2 1.2 1 0 0 1 1 1 0 DGC domain APP_N PF02177.14 MSTRG.46701.1_2 - 1.9e-14 53.7 0.0 2.5e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding DUF4337 PF14235.4 MSTRG.98867.1_3 - 0.09 12.7 0.2 0.09 12.7 0.2 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Miga PF10265.7 MSTRG.136809.1_3 - 0.033 13.0 0.1 0.038 12.8 0.1 1.0 1 0 0 1 1 1 0 Mitoguardin HnRNPA1 PF11627.6 MSTRG.24834.1_3 - 1.3e-15 57.1 24.8 1.3e-15 57.1 24.8 3.2 4 0 0 4 4 4 1 Nuclear factor hnRNPA1 DUF2973 PF11189.6 MSTRG.83971.1_2 - 0.31 11.0 3.5 0.66 10.0 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) TPR_11 PF13414.4 MSTRG.125239.1_3 - 1.9e-19 68.9 7.9 1.6e-11 43.5 0.4 4.1 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.26 MSTRG.125239.1_3 - 1.2e-17 62.8 6.1 4.6e-11 41.9 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.15 MSTRG.125239.1_3 - 1.1e-16 59.3 5.5 4.3e-09 35.7 0.4 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.4 MSTRG.125239.1_3 - 1.3e-14 53.0 0.4 1.8e-07 30.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.4 MSTRG.125239.1_3 - 2.4e-12 47.0 1.5 4.9e-06 26.8 1.5 3.3 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.4 MSTRG.125239.1_3 - 6.6e-12 45.1 2.3 8.8e-05 22.9 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.4 MSTRG.125239.1_3 - 1.4e-10 40.6 11.2 2.8e-07 30.1 0.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.4 MSTRG.125239.1_3 - 1.4e-10 41.2 5.4 2.8e-07 30.6 0.3 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.4 MSTRG.125239.1_3 - 3.5e-10 40.3 4.0 0.00018 22.0 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.4 MSTRG.125239.1_3 - 5.4e-10 38.8 3.5 8.2e-05 22.6 0.1 3.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.4 MSTRG.125239.1_3 - 7.4e-10 38.0 5.2 1.3e-05 24.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.7 MSTRG.125239.1_3 - 3.3e-05 23.6 0.5 0.001 18.8 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain NARP1 PF12569.6 MSTRG.125239.1_3 - 3.8e-05 22.7 0.0 4.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_4 PF07721.12 MSTRG.125239.1_3 - 6.4e-05 23.1 6.4 2.2 9.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.4 MSTRG.125239.1_3 - 0.0016 18.8 1.7 4 8.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.4 MSTRG.125239.1_3 - 0.0064 16.5 5.2 0.058 13.4 0.6 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.4 MSTRG.125239.1_3 - 0.01 14.9 1.4 0.13 11.3 1.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.7 MSTRG.125239.1_3 - 0.011 15.3 0.8 3.7 7.0 0.1 3.0 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_20 PF14561.4 MSTRG.125239.1_3 - 0.025 14.7 1.1 1.1 9.4 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 MSTRG.125239.1_3 - 0.05 13.5 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 1 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.16 MSTRG.125239.1_3 - 0.07 13.1 4.0 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Myosin_tail_1 PF01576.17 MSTRG.120474.1_2 - 1.7e-109 367.1 76.9 1.9e-109 367.0 76.9 1.0 1 0 0 1 1 1 1 Myosin tail CALCOCO1 PF07888.9 MSTRG.120474.1_2 - 0.0047 15.4 59.7 0.098 11.1 22.1 2.0 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.10 MSTRG.120474.1_2 - 0.015 15.2 19.5 0.015 15.2 19.5 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.10 MSTRG.120474.1_2 - 0.11 11.7 12.0 0.15 11.3 3.9 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.9 MSTRG.120474.1_2 - 0.12 12.5 66.7 0.068 13.2 22.1 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) SF-assemblin PF06705.9 MSTRG.120474.1_2 - 0.63 9.2 48.4 4.5 6.4 18.4 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF5082 PF16888.3 MSTRG.120474.1_2 - 0.69 10.1 43.5 0.14 12.4 19.3 4.3 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) MAD PF05557.11 MSTRG.120474.1_2 - 0.84 7.8 60.2 2.6 6.1 41.1 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein IncA PF04156.12 MSTRG.120474.1_2 - 0.88 9.2 66.3 7.3 6.2 27.4 3.1 1 1 1 2 2 2 0 IncA protein ERM PF00769.17 MSTRG.120474.1_2 - 1 9.0 73.4 4.5 6.9 27.9 3.0 1 1 2 3 3 3 0 Ezrin/radixin/moesin family ADIP PF11559.6 MSTRG.120474.1_2 - 1.5 8.8 60.6 1.6 8.7 13.5 4.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.8 MSTRG.120474.1_2 - 1.9 8.6 42.5 2.2 8.3 12.7 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family BST2 PF16716.3 MSTRG.120474.1_2 - 3.2 8.2 57.5 0.55 10.7 11.6 4.8 1 1 4 5 5 5 0 Bone marrow stromal antigen 2 DUF3450 PF11932.6 MSTRG.120474.1_2 - 4.2 6.4 55.0 0.12 11.5 18.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF1664 PF07889.10 MSTRG.120474.1_2 - 4.7 7.1 39.8 1.2 9.0 7.1 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Cortex-I_coil PF09304.8 MSTRG.120474.1_2 - 4.9 7.3 60.1 0.12 12.4 16.4 4.5 1 1 2 3 3 3 0 Cortexillin I, coiled coil HOOK PF05622.10 MSTRG.120474.1_2 - 8.6 4.2 62.7 5.6 4.8 25.7 2.1 1 1 1 2 2 2 0 HOOK protein Baculo_PEP_C PF04513.10 MSTRG.120474.1_2 - 9.4 6.1 24.0 8.3 6.3 2.2 3.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exo_endo_phos_2 PF14529.4 MSTRG.97217.1_1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF2284 PF10050.7 MSTRG.97217.1_1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) CSD PF00313.20 MSTRG.119318.2_1 - 2e-81 267.7 17.1 2e-16 59.4 0.3 9.3 9 0 0 9 9 9 8 'Cold-shock' DNA-binding domain S1-like PF14444.4 MSTRG.119318.2_1 - 6.6e-13 48.4 4.7 0.057 13.4 0.0 6.8 6 0 0 6 6 6 4 S1-like SUZ-C PF12901.5 MSTRG.119318.2_1 - 2.2e-09 37.0 0.3 9.1e-09 35.0 0.0 2.3 2 0 0 2 2 2 1 SUZ-C motif CusF_Ec PF11604.6 MSTRG.119318.2_1 - 6.3e-08 32.3 8.3 0.22 11.4 0.1 7.4 8 0 0 8 8 8 2 Copper binding periplasmic protein CusF OB_RNB PF08206.9 MSTRG.119318.2_1 - 0.6 9.7 13.0 24 4.6 0.2 5.4 6 0 0 6 6 6 0 Ribonuclease B OB domain MazE_antitoxin PF04014.16 MSTRG.119318.2_1 - 1.2 9.0 6.6 18 5.3 0.1 4.3 5 0 0 5 5 5 0 Antidote-toxin recognition MazE, bacterial antitoxin Prion_bPrPp PF11587.6 MSTRG.119318.2_3 - 0.76 9.5 2.9 2.1 8.1 2.9 1.7 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal SAM_1 PF00536.28 MSTRG.138359.1_1 - 5.4e-19 68.3 0.1 6.1e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 MSTRG.138359.1_1 - 6.7e-09 35.6 0.1 8e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.14 MSTRG.138359.1_1 - 0.024 14.5 0.4 0.066 13.1 0.4 1.7 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Trypsin PF00089.24 MSTRG.124203.1_1 - 2.2e-11 43.8 0.0 2.8e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin HTH_Tnp_Tc3_2 PF01498.16 MSTRG.101064.1_2 - 4.2e-05 23.6 0.2 8.4e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.101064.1_3 - 5.1e-11 42.5 0.3 1.2e-10 41.3 0.1 1.7 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.4 MSTRG.101064.1_3 - 2e-06 27.3 0.4 0.00039 20.0 0.0 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.101064.1_3 - 1.8e-05 25.1 0.8 0.00013 22.4 0.9 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_4 PF13613.4 MSTRG.101064.1_3 - 0.047 13.4 0.2 5.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.4 MSTRG.101064.1_3 - 0.066 12.9 1.5 8.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.20 MSTRG.101064.1_3 - 0.093 12.7 0.0 19 5.3 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix HTH_7 PF02796.13 MSTRG.101064.1_3 - 0.22 11.5 1.7 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase RVT_1 PF00078.25 MSTRG.65992.1_2 - 7.9e-05 22.1 0.0 9.3e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UQ_con PF00179.24 MSTRG.135037.1_2 - 1.1e-05 25.0 0.0 1.2e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LTXXQ PF07813.10 MSTRG.24187.1_1 - 0.0037 17.8 0.2 0.042 14.4 0.1 2.2 2 0 0 2 2 2 1 LTXXQ motif family protein DUF601 PF04642.10 MSTRG.24187.1_1 - 0.12 11.8 5.0 0.15 11.4 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 RRN9 PF10680.7 MSTRG.92191.1_2 - 0.16 12.2 0.1 0.28 11.4 0.1 1.4 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor MSL1_dimer PF16801.3 MSTRG.95127.1_2 - 0.024 14.3 2.2 0.024 14.3 2.2 1.7 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 zf-C2HC_2 PF13913.4 MSTRG.112308.2_2 - 0.048 13.4 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.24 MSTRG.112308.2_2 - 0.063 13.6 0.1 0.063 13.6 0.1 2.4 2 1 1 3 3 3 0 Zinc finger, C2H2 type DBINO PF13892.4 MSTRG.112308.2_2 - 0.082 13.1 7.6 0.12 12.5 7.6 1.2 1 0 0 1 1 1 0 DNA-binding domain zf-C2H2_4 PF13894.4 MSTRG.112308.2_2 - 0.11 13.3 0.1 0.11 13.3 0.1 2.1 3 0 0 3 3 3 0 C2H2-type zinc finger LRR_8 PF13855.4 MSTRG.142822.2_2 - 1.5e-06 27.8 2.2 2.3e-06 27.1 1.6 1.6 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.5 MSTRG.142822.2_2 - 6.5e-05 23.1 2.5 0.00017 21.7 1.3 2.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 MSTRG.142822.2_2 - 0.027 14.8 5.4 0.66 10.5 3.2 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat Tmemb_55A PF09788.7 MSTRG.142822.2_3 - 0.0096 14.9 2.9 0.013 14.4 2.9 1.2 1 0 0 1 1 1 1 Transmembrane protein 55A TRAM_LAG1_CLN8 PF03798.14 MSTRG.39848.1_2 - 3.8e-21 75.6 13.8 4.1e-21 75.5 13.8 1.0 1 0 0 1 1 1 1 TLC domain Sarcoglycan_1 PF04790.11 MSTRG.39848.1_2 - 0.047 12.9 2.1 0.072 12.3 2.1 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein DUF4744 PF15918.3 MSTRG.5082.1_1 - 0.025 15.3 0.1 0.086 13.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) NPV_P10 PF05531.10 MSTRG.5082.1_1 - 0.064 13.6 0.0 0.084 13.2 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein I-set PF07679.14 MSTRG.117729.1_3 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain fn3 PF00041.19 MSTRG.117729.1_3 - 0.00012 22.3 0.1 0.00018 21.6 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain ig PF00047.23 MSTRG.117729.1_3 - 0.00048 20.1 0.2 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.4 MSTRG.117729.1_3 - 0.0059 17.1 0.2 0.035 14.6 0.0 2.0 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 MSTRG.117729.1_3 - 0.12 12.5 0.3 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 Immunoglobulin V-set domain Herpes_UL4 PF03277.11 MSTRG.17294.1_1 - 0.048 13.1 0.2 0.064 12.7 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL4 family RVT_1 PF00078.25 MSTRG.17294.1_2 - 0.019 14.3 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) BHD_2 PF10404.7 MSTRG.1632.1_3 - 0.13 13.1 0.1 0.23 12.3 0.1 1.3 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 bZIP_1 PF00170.19 MSTRG.137547.1_3 - 1.8e-19 69.5 11.9 2.2e-19 69.2 11.9 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 MSTRG.137547.1_3 - 2.3e-08 33.9 12.3 3.4e-08 33.3 12.3 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 MSTRG.137547.1_3 - 0.00012 22.3 2.2 0.00017 21.9 2.2 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF4988 PF16378.3 MSTRG.137547.1_3 - 0.2 11.1 0.2 0.26 10.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function V-set PF07686.15 MSTRG.31940.2_3 - 0.0014 18.6 0.1 0.0029 17.6 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain VSP PF03302.11 MSTRG.31940.2_3 - 0.0026 16.6 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF1510 PF07423.9 MSTRG.31940.2_3 - 0.0075 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) ig PF00047.23 MSTRG.31940.2_3 - 0.013 15.5 0.3 0.037 14.0 0.3 1.7 1 0 0 1 1 1 0 Immunoglobulin domain DUF4834 PF16118.3 MSTRG.31940.2_3 - 0.016 16.0 0.0 0.033 15.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Izumo-Ig PF16706.3 MSTRG.31940.2_3 - 0.019 14.9 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain MAP17 PF15807.3 MSTRG.31940.2_3 - 0.036 14.2 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Ig_3 PF13927.4 MSTRG.31940.2_3 - 0.062 13.8 0.1 0.17 12.4 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin domain P12 PF12669.5 MSTRG.31940.2_3 - 0.12 12.7 1.1 0.2 12.0 1.1 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Ig_4 PF16680.3 MSTRG.31940.2_3 - 0.42 10.9 2.4 0.45 10.8 0.1 2.1 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Lig_chan PF00060.24 MSTRG.31940.2_3 - 0.63 9.7 3.3 1.7 8.3 3.3 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel DUF4690 PF15756.3 MSTRG.31940.2_3 - 8.6 6.9 9.4 0.73 10.3 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4690) C_tripleX PF02363.17 MSTRG.133850.1_2 - 1.2 9.5 8.2 1e+02 3.4 8.2 2.5 1 1 0 1 1 1 0 Cysteine rich repeat FACT-Spt16_Nlob PF14826.4 MSTRG.37488.1_2 - 9e-53 178.3 1.2 9e-53 178.3 1.2 1.6 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.22 MSTRG.37488.1_2 - 0.014 14.9 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 WD40 PF00400.30 MSTRG.137374.1_3 - 5.7e-16 58.5 4.1 0.0005 20.7 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.137374.1_3 - 0.00023 21.3 0.5 0.23 11.6 0.0 3.0 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 MSTRG.137374.1_3 - 0.0024 16.4 0.6 0.12 10.9 0.3 2.4 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.9 MSTRG.137374.1_3 - 0.17 10.5 0.1 1.3 7.6 0.0 1.9 1 1 1 2 2 2 0 Nup133 N terminal like AAA PF00004.27 MSTRG.23021.1_2 - 0.052 13.9 0.0 0.066 13.5 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RasGEF PF00617.17 MSTRG.137111.1_2 - 0.0055 16.8 0.0 0.0055 16.8 0.0 1.0 1 0 0 1 1 1 1 RasGEF domain Antimicrobial12 PF08107.9 MSTRG.137111.1_3 - 0.025 14.2 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Pleurocidin family MIT PF04212.16 MSTRG.46437.1_2 - 1.4e-05 25.0 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF2387 PF09526.8 MSTRG.46437.1_2 - 0.12 12.4 0.1 0.82 9.7 0.0 2.0 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Defensin_2 PF01097.16 MSTRG.131947.1_2 - 1.1 9.1 4.6 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Arthropod defensin Orn_Arg_deC_N PF02784.14 MSTRG.75005.1_1 - 7.7e-45 153.1 0.0 9.2e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 MSTRG.75005.1_1 - 7.6e-13 48.4 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 MSTRG.75005.1_1 - 0.0072 15.7 0.0 0.013 14.8 0.0 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel I-set PF07679.14 MSTRG.50850.1_1 - 3.2e-178 578.3 1.9 2.2e-19 69.2 0.0 12.4 12 0 0 12 12 12 12 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.50850.1_1 - 4.8e-106 347.4 0.0 1e-11 45.2 0.0 12.7 12 0 0 12 12 12 12 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.50850.1_1 - 1.6e-52 175.6 0.6 6.6e-09 35.9 0.1 11.8 12 0 0 12 12 12 8 Immunoglobulin domain ig PF00047.23 MSTRG.50850.1_1 - 1.2e-49 166.3 3.9 2e-08 34.1 0.1 11.6 12 1 1 13 13 13 9 Immunoglobulin domain C2-set_2 PF08205.10 MSTRG.50850.1_1 - 8.6e-18 64.1 5.6 0.033 14.1 0.0 10.2 10 0 0 10 10 10 5 CD80-like C2-set immunoglobulin domain V-set PF07686.15 MSTRG.50850.1_1 - 4.2e-13 49.3 2.5 0.28 11.2 0.0 10.7 10 4 0 10 10 10 2 Immunoglobulin V-set domain Ig_5 PF16681.3 MSTRG.50850.1_1 - 2.8e-05 24.3 5.9 0.072 13.4 0.0 6.8 8 0 0 8 8 8 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DDE_2 PF02914.13 MSTRG.50850.1_1 - 0.00075 19.2 0.1 0.074 12.6 0.0 2.3 2 0 0 2 2 2 1 Bacteriophage Mu transposase Izumo-Ig PF16706.3 MSTRG.50850.1_1 - 0.0064 16.4 0.0 0.061 13.2 0.0 2.9 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 MSTRG.50850.1_1 - 0.14 12.3 0.0 9.6 6.3 0.0 3.6 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 DUF2914 PF11141.6 MSTRG.50850.1_1 - 0.14 11.8 0.8 1.4 8.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) I-set PF07679.14 MSTRG.50850.1_3 - 3.8e-77 254.3 23.1 3.5e-10 39.7 0.1 8.7 9 0 0 9 9 9 8 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.50850.1_3 - 7.4e-40 135.3 7.6 9.3e-07 29.2 0.0 8.7 9 0 0 9 9 9 8 Immunoglobulin domain ig PF00047.23 MSTRG.50850.1_3 - 4e-14 52.4 14.0 0.0038 17.2 0.0 8.2 9 0 0 9 9 9 5 Immunoglobulin domain DIPSY PF11763.6 MSTRG.50850.1_3 - 0.074 13.1 0.0 8.5 6.4 0.0 2.8 3 0 0 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal Collagen PF01391.16 MSTRG.22436.1_1 - 2.3e-18 65.6 65.0 5.7e-10 38.7 30.2 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) STAT_bind PF02864.13 MSTRG.120801.1_3 - 9.4e-77 258.1 0.1 9.4e-77 258.1 0.1 1.9 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.18 MSTRG.120801.1_3 - 4.8e-55 186.1 16.6 1e-54 185.0 16.6 1.6 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.15 MSTRG.120801.1_3 - 1.6e-37 128.5 9.5 1.6e-37 128.5 9.5 2.8 2 1 0 2 2 2 1 STAT protein, protein interaction domain SH2 PF00017.22 MSTRG.120801.1_3 - 1.4e-11 44.1 0.0 3.3e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain PRKCSH-like PF12999.5 MSTRG.120801.1_3 - 0.8 9.3 3.7 0.89 9.2 0.0 2.6 3 0 0 3 3 3 0 Glucosidase II beta subunit-like Fib_alpha PF08702.8 MSTRG.120801.1_3 - 1.9 8.5 9.0 0.84 9.7 4.3 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF342 PF03961.11 MSTRG.120801.1_3 - 3.1 6.2 10.3 0.32 9.4 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF3265 PF11665.6 MSTRG.127047.1_3 - 3.1 8.0 8.1 1e+02 3.1 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3265) FmdE PF02663.12 MSTRG.56580.1_1 - 0.014 15.3 0.5 0.016 15.1 0.5 1.1 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Peptidase_C2 PF00648.19 MSTRG.51084.1_1 - 1.2e-49 168.8 0.0 1.3e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Polysacc_deac_3 PF15421.4 MSTRG.76314.1_1 - 0.02 13.3 0.3 0.024 13.0 0.3 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase Tubulin PF00091.23 MSTRG.49451.2_2 - 3.5e-19 69.7 0.0 4.2e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Myb_DNA-bind_4 PF13837.4 MSTRG.29664.1_1 - 5.7e-06 26.5 0.0 8.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.7 MSTRG.29664.1_1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.29 MSTRG.29664.1_1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.5 MSTRG.29664.1_1 - 0.059 14.1 0.2 0.14 12.9 0.0 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Activin_recp PF01064.21 MSTRG.79875.1_1 - 8.6e-07 29.8 12.3 1.6e-06 29.0 12.3 1.4 1 0 0 1 1 1 1 Activin types I and II receptor domain Toxin_1 PF00087.19 MSTRG.79875.1_1 - 0.013 15.6 9.4 0.032 14.3 9.4 1.6 1 0 0 1 1 1 0 Snake toxin DDE_3 PF13358.4 MSTRG.34277.1_2 - 4.3e-05 23.2 0.1 5.9e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease CpcD PF01383.19 MSTRG.24449.1_1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain DUF1067 PF06362.9 MSTRG.120651.1_2 - 0.087 13.5 0.0 0.1 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) WD40 PF00400.30 MSTRG.38841.1_3 - 3.7e-16 59.1 5.2 0.00013 22.5 0.1 5.7 4 1 1 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.38841.1_3 - 2.8e-06 27.4 0.2 0.011 15.9 0.1 3.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 MSTRG.38841.1_3 - 0.0046 16.7 0.0 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A LINES_C PF14695.4 MSTRG.44363.1_3 - 0.025 13.9 0.4 0.047 13.0 0.4 1.5 1 0 0 1 1 1 0 Lines C-terminus ArgoMid PF16487.3 MSTRG.34529.1_3 - 5.6e-26 90.5 0.2 6.1e-26 90.4 0.2 1.0 1 0 0 1 1 1 1 Mid domain of argonaute EF-hand_6 PF13405.4 MSTRG.28694.1_2 - 6.9e-05 22.3 0.0 0.00017 21.2 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.4 MSTRG.28694.1_2 - 0.013 15.8 0.2 0.035 14.5 0.2 1.7 1 1 0 1 1 1 0 EF-hand domain pair DUF3464 PF11947.6 MSTRG.103113.1_1 - 0.27 10.9 0.6 0.36 10.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) MATH PF00917.24 MSTRG.103113.1_3 - 0.0069 16.4 0.1 0.0079 16.2 0.1 1.1 1 0 0 1 1 1 1 MATH domain SNF PF00209.16 MSTRG.73452.1_1 - 1.1e-76 258.5 8.5 1.6e-76 258.0 8.5 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.16 MSTRG.73452.1_2 - 1.6e-38 132.6 0.4 1.6e-38 132.6 0.4 1.5 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family GH3 PF03321.11 MSTRG.2623.1_3 - 8.4e-41 140.3 0.1 8.9e-41 140.2 0.1 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter MmlI PF09448.8 MSTRG.2623.1_3 - 0.17 12.2 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase DUF3973 PF13119.4 MSTRG.2687.1_1 - 0.0015 18.6 2.5 0.2 11.8 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3973) IL4Ra_N PF09238.8 MSTRG.2687.1_2 - 0.0032 17.6 0.6 0.0069 16.6 0.6 1.5 1 0 0 1 1 1 1 Interleukin-4 receptor alpha chain, N-terminal zf-RING_2 PF13639.4 MSTRG.43575.1_3 - 4.4e-08 33.1 3.0 6e-08 32.7 3.0 1.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.4 MSTRG.43575.1_3 - 1.8e-06 27.6 2.2 2.8e-06 27.0 2.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 MSTRG.43575.1_3 - 2.4e-06 27.3 1.1 2.4e-06 27.3 1.1 1.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 MSTRG.43575.1_3 - 2.6e-06 27.2 2.3 3.3e-06 26.8 2.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.23 MSTRG.43575.1_3 - 2.9e-06 26.9 1.8 4.1e-06 26.4 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 MSTRG.43575.1_3 - 1e-05 25.1 3.9 1.7e-05 24.4 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_6 PF14599.4 MSTRG.43575.1_3 - 1.3e-05 24.9 1.0 2.7e-05 24.0 1.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon zf-RING_4 PF14570.4 MSTRG.43575.1_3 - 0.00017 21.1 1.0 0.0003 20.3 1.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.4 MSTRG.43575.1_3 - 0.00091 18.9 3.1 0.0013 18.4 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 MSTRG.43575.1_3 - 0.0068 16.5 2.4 0.01 16.0 2.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 MSTRG.43575.1_3 - 0.0084 15.7 2.3 0.0084 15.7 2.3 2.1 1 1 1 2 2 2 1 RING-like zinc finger zf-RING-like PF08746.9 MSTRG.43575.1_3 - 0.034 14.3 1.1 0.059 13.6 1.1 1.4 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.3 MSTRG.43575.1_3 - 0.55 9.8 5.3 0.27 10.7 1.5 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Ins145_P3_rec PF08709.9 MSTRG.27878.1_2 - 2.3e-30 105.2 0.0 2.5e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.17 MSTRG.27878.1_2 - 0.00067 19.4 0.1 0.00076 19.2 0.1 1.1 1 0 0 1 1 1 1 MIR domain DUF4971 PF16341.3 MSTRG.88620.1_1 - 0.15 11.7 0.0 0.35 10.6 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4971) Homeobox PF00046.27 MSTRG.66173.2_2 - 7.1e-13 48.0 1.5 8.7e-13 47.8 1.5 1.1 1 0 0 1 1 1 1 Homeobox domain XPA_C PF05181.10 MSTRG.23125.1_1 - 0.0052 16.6 0.5 0.0085 15.9 0.5 1.3 1 0 0 1 1 1 1 XPA protein C-terminus Cofilin_ADF PF00241.18 MSTRG.23125.1_3 - 3.8e-25 88.4 0.6 4.7e-25 88.1 0.6 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF106 PF01956.14 MSTRG.119606.1_3 - 1e-32 113.0 0.4 1.2e-32 112.9 0.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 TRAM1 PF08390.9 MSTRG.119606.1_3 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 TRAM1-like protein DUF3671 PF12420.6 MSTRG.119606.1_3 - 0.045 13.7 0.1 0.065 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function Baculo_PEP_C PF04513.10 MSTRG.134845.1_2 - 0.023 14.6 3.4 0.045 13.7 3.4 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PAP_assoc PF03828.17 MSTRG.49953.1_3 - 0.00046 20.2 0.1 0.00058 19.9 0.1 1.2 1 0 0 1 1 1 1 Cid1 family poly A polymerase Ricin_B_lectin PF00652.20 MSTRG.44667.1_1 - 0.00047 20.3 0.2 0.00057 20.0 0.2 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF4603 PF15376.4 MSTRG.99879.4_1 - 0.29 8.4 1.2 0.38 7.9 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) PDZ PF00595.22 MSTRG.51320.1_1 - 3.1e-11 43.3 0.3 5.2e-11 42.6 0.3 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.15 MSTRG.51320.1_1 - 5.3e-07 29.1 0.0 1.4e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 MSTRG.51320.1_1 - 5.7e-07 28.9 0.2 3.3e-06 26.5 0.2 2.2 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.4 MSTRG.51320.1_1 - 4.6e-05 23.5 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.4 MSTRG.51320.1_1 - 0.0033 17.1 0.0 0.0083 15.8 0.0 1.7 1 1 0 1 1 1 1 Variant SH3 domain Tricorn_PDZ PF14685.4 MSTRG.51320.1_1 - 0.0075 16.1 0.0 0.074 12.9 0.0 2.4 2 1 0 2 2 2 1 Tricorn protease PDZ domain IRK PF01007.18 MSTRG.103036.1_2 - 1.2e-126 422.0 0.3 1.5e-126 421.7 0.3 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.14 MSTRG.103036.1_2 - 0.047 13.5 6.9 0.13 12.2 6.9 1.7 1 0 0 1 1 1 0 Ion channel HTH_Tnp_Tc3_2 PF01498.16 MSTRG.78971.1_3 - 9.3e-19 67.3 2.3 1.2e-18 67.0 2.3 1.2 1 0 0 1 1 1 1 Transposase Arg_repressor PF01316.19 MSTRG.78971.1_3 - 0.018 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_32 PF13565.4 MSTRG.78971.1_3 - 0.02 15.4 0.1 0.031 14.8 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_33 PF13592.4 MSTRG.78971.1_3 - 0.048 13.2 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix DUF3508 PF12018.6 MSTRG.39842.1_3 - 0.0017 17.8 5.7 0.0023 17.4 5.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3508) FAM184 PF15665.3 MSTRG.39842.1_3 - 0.0075 15.9 14.9 0.012 15.3 14.9 1.3 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B zf-C4H2 PF10146.7 MSTRG.39842.1_3 - 0.21 11.7 14.0 0.18 11.9 2.4 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein NPV_P10 PF05531.10 MSTRG.39842.1_3 - 0.28 11.5 2.3 1.6 9.1 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.4 MSTRG.39842.1_3 - 0.39 9.2 10.4 1.1 7.6 10.4 1.6 1 1 0 1 1 1 0 AAA domain APG6 PF04111.10 MSTRG.39842.1_3 - 0.57 9.4 13.9 0.8 8.9 13.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ZYG-11_interact PF05884.10 MSTRG.39842.1_3 - 0.59 9.4 1.2 0.71 9.1 1.2 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Spore_III_AB PF09548.8 MSTRG.39842.1_3 - 0.74 9.8 6.3 2.1 8.3 1.1 2.4 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF1664 PF07889.10 MSTRG.39842.1_3 - 3.3 7.6 10.8 3.7 7.4 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.9 MSTRG.39842.1_3 - 3.4 8.2 11.1 89 3.6 11.1 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Med9 PF07544.11 MSTRG.39842.1_3 - 5.8 6.9 12.3 1.4 8.9 2.3 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CENP-Q PF13094.4 MSTRG.39842.1_3 - 6.6 6.8 15.3 9 6.3 15.3 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FUSC PF04632.10 MSTRG.39842.1_3 - 6.9 5.0 4.7 9.2 4.6 4.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1690 PF07956.9 MSTRG.39842.1_3 - 9.4 6.5 15.4 2.5 8.4 4.5 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) KH_1 PF00013.27 MSTRG.63124.1_2 - 0.11 12.2 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 KH domain CUB PF00431.18 MSTRG.96339.1_3 - 8.4e-50 167.6 0.3 3.4e-43 146.3 0.2 2.1 2 0 0 2 2 2 2 CUB domain Radical_SAM PF04055.19 MSTRG.20172.1_1 - 0.81 9.9 3.1 0.85 9.8 3.1 1.1 1 0 0 1 1 1 0 Radical SAM superfamily Sugar_tr PF00083.22 MSTRG.20172.1_3 - 1.6e-11 43.6 0.0 1.6e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter HELP PF03451.12 MSTRG.141626.1_2 - 7.5e-30 102.5 0.1 1.3e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 HELP motif WD40 PF00400.30 MSTRG.141626.1_2 - 4.9e-22 77.7 29.9 0.0011 19.6 0.3 9.6 10 1 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.141626.1_2 - 4.6e-07 29.9 0.1 0.014 15.5 0.0 5.0 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Glyoxalase PF00903.23 MSTRG.96067.1_3 - 4.7e-06 26.7 0.0 6.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.4 MSTRG.96067.1_3 - 0.00031 20.9 0.0 0.00084 19.5 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily VWA_2 PF13519.4 MSTRG.58450.1_1 - 4.6e-25 88.2 0.0 9.2e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.12 MSTRG.58450.1_1 - 2.9e-08 33.6 0.1 4.1e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.26 MSTRG.58450.1_1 - 1.7e-06 28.3 0.0 2.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.18 MSTRG.58450.1_3 - 1.4e-08 33.9 4.2 6.4e-05 22.5 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif FmdE PF02663.12 MSTRG.97665.1_2 - 0.32 10.9 1.7 0.58 10.1 1.7 1.4 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon RRM_5 PF13893.4 MSTRG.47089.1_2 - 2.4e-11 43.2 0.1 3.4e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 MSTRG.47089.1_2 - 1.1e-05 25.0 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med20 PF08612.9 MSTRG.82818.1_1 - 0.19 10.9 0.1 0.26 10.5 0.1 1.1 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Imm35 PF15567.4 MSTRG.103941.1_2 - 0.11 12.5 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 35 DUF1891 PF09004.8 MSTRG.103941.1_3 - 1.4e-05 24.4 2.4 2.6e-05 23.6 2.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) EII-Sor PF03609.12 MSTRG.134107.1_2 - 0.0049 16.2 1.0 0.0061 15.9 1.0 1.1 1 0 0 1 1 1 1 PTS system sorbose-specific iic component VESA1_N PF12785.5 MSTRG.134107.1_2 - 0.2 10.4 5.3 0.28 10.0 5.3 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 COX2-transmemb PF09125.8 MSTRG.134107.1_2 - 2.3 8.0 4.2 8.6 6.1 4.2 1.9 1 1 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane DENN PF02141.19 MSTRG.31379.1_3 - 0.02 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 DENN (AEX-3) domain RGM_C PF06534.11 MSTRG.62071.1_1 - 5.4e-20 71.5 0.1 7.8e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RNA_pol_I_A49 PF06870.10 MSTRG.118692.1_3 - 2.8e-11 42.8 0.1 3.5e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Kunitz_BPTI PF00014.21 MSTRG.77443.1_3 - 1.6e-11 44.1 7.9 2.1e-11 43.7 7.9 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain KH_1 PF00013.27 MSTRG.132207.3_3 - 8.6e-24 83.0 1.4 2.6e-11 43.0 0.2 2.2 2 0 0 2 2 2 2 KH domain ROKNT PF08067.9 MSTRG.132207.3_3 - 2.6e-23 81.9 10.1 4.1e-23 81.2 10.1 1.3 1 0 0 1 1 1 1 ROKNT (NUC014) domain KH_2 PF07650.15 MSTRG.132207.3_3 - 3.5e-09 36.2 3.5 0.00021 20.9 0.2 2.6 1 1 1 2 2 2 2 KH domain KH_4 PF13083.4 MSTRG.132207.3_3 - 3.3e-08 33.2 0.4 1.5e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 KH domain DJ-1_PfpI PF01965.22 MSTRG.132207.3_3 - 0.0042 16.8 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family KH_5 PF13184.4 MSTRG.132207.3_3 - 0.053 13.5 4.2 0.81 9.7 0.3 2.7 1 1 1 2 2 2 0 NusA-like KH domain CHGN PF05679.14 MSTRG.57952.1_3 - 1e-16 60.8 0.3 1.1e-16 60.6 0.3 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase HTH_23 PF13384.4 MSTRG.22504.1_3 - 0.00015 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.4 MSTRG.22504.1_3 - 0.00027 20.5 0.1 0.00046 19.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.10 MSTRG.22504.1_3 - 0.0009 18.7 0.1 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.17 MSTRG.22504.1_3 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_24 PF13412.4 MSTRG.22504.1_3 - 0.028 13.9 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.4 MSTRG.22504.1_3 - 0.058 13.3 0.3 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.13 MSTRG.22504.1_3 - 0.072 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Terminase_5 PF06056.10 MSTRG.22504.1_3 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) TetR_N PF00440.21 MSTRG.22504.1_3 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Cyclin_N PF00134.21 MSTRG.18477.1_2 - 5.9e-30 103.5 0.0 7.9e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_N2 PF16500.3 MSTRG.18477.1_2 - 5.2e-08 33.6 0.4 8.3e-08 32.9 0.4 1.3 1 0 0 1 1 1 1 N-terminal region of cyclin_N AAA_12 PF13087.4 MSTRG.102277.1_3 - 4.9e-41 140.4 0.0 9.3e-41 139.5 0.0 1.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.16 MSTRG.102277.1_3 - 2.1e-05 24.3 0.0 0.00074 19.2 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.4 MSTRG.102277.1_3 - 0.00083 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaJ PF00226.29 MSTRG.56732.1_3 - 2.4e-20 72.3 0.1 3.4e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain YkyA PF10368.7 MSTRG.56732.1_3 - 0.044 13.4 0.2 0.055 13.1 0.2 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein HECT PF00632.23 MSTRG.115119.1_1 - 1.3e-37 129.8 0.0 1.5e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_M16_C PF05193.19 MSTRG.49416.1_1 - 4.2e-10 39.8 0.1 4.6e-10 39.7 0.1 1.0 1 0 0 1 1 1 1 Peptidase M16 inactive domain EF-hand_2 PF09068.9 MSTRG.62514.1_3 - 6.4e-35 119.8 1.4 8.5e-35 119.4 1.4 1.1 1 0 0 1 1 1 1 EF hand RVT_1 PF00078.25 MSTRG.12693.1_3 - 1.7e-08 34.2 0.0 1.9e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GASA PF02704.12 MSTRG.29195.1_3 - 0.28 11.3 4.9 0.69 10.0 4.9 1.7 1 0 0 1 1 1 0 Gibberellin regulated protein Syntaxin-5_N PF11416.6 MSTRG.33293.2_3 - 4.6e-11 41.5 0.4 9.2e-11 40.5 0.4 1.5 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain DUF4106 PF13388.4 MSTRG.33293.2_3 - 0.46 9.5 2.3 0.48 9.5 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Mtp PF03821.14 MSTRG.121011.1_1 - 0.04 13.4 0.0 0.04 13.4 0.0 1.0 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Calsarcin PF05556.9 MSTRG.39222.2_1 - 2.2e-82 276.0 0.0 2.7e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) PHD PF00628.27 MSTRG.425.1_3 - 2.6e-13 49.5 44.6 8e-08 31.9 18.5 2.8 2 1 1 3 3 3 2 PHD-finger zf-PHD-like PF15446.4 MSTRG.425.1_3 - 0.045 13.2 26.2 0.35 10.3 13.2 2.9 2 2 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.4 MSTRG.425.1_3 - 0.71 9.3 39.4 0.33 10.4 10.3 3.9 2 2 1 3 3 3 0 PHD-finger DUF3567 PF12091.6 MSTRG.103858.1_1 - 0.15 12.1 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) 7tm_1 PF00001.19 MSTRG.132975.1_3 - 2.5e-35 121.9 5.9 3.6e-35 121.4 5.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 MSTRG.132975.1_3 - 6.4e-09 35.4 4.6 8.8e-09 35.0 4.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 MSTRG.132975.1_3 - 1.2e-07 31.2 4.9 1.5e-07 30.9 4.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 MSTRG.132975.1_3 - 0.00069 19.3 4.0 0.0015 18.2 4.0 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.7 MSTRG.132975.1_3 - 0.0026 17.0 1.8 0.0026 17.0 1.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv Serpentine_r_xa PF03383.13 MSTRG.132975.1_3 - 0.0093 15.8 2.8 0.0093 15.8 2.8 1.7 1 1 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa RhoGEF PF00621.18 MSTRG.50338.1_2 - 1e-09 38.8 0.3 1.8e-09 38.0 0.1 1.5 2 0 0 2 2 2 1 RhoGEF domain Zona_pellucida PF00100.21 MSTRG.108796.1_2 - 1e-15 58.1 0.0 1.1e-15 58.0 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain 1-cysPrx_C PF10417.7 MSTRG.86604.1_2 - 0.17 11.6 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin GPHH PF16905.3 MSTRG.31470.1_2 - 4.5e-38 128.8 0.0 1.7e-37 126.9 0.0 1.9 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.9 MSTRG.31470.1_2 - 3.1e-30 104.1 0.1 9.4e-30 102.6 0.1 1.9 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain Ion_trans PF00520.29 MSTRG.31470.1_2 - 5.3e-10 38.8 2.4 8.9e-10 38.1 2.4 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.10 MSTRG.31470.1_2 - 0.0034 16.0 3.1 0.0058 15.2 3.1 1.4 1 0 0 1 1 1 1 Polycystin cation channel EF-hand_1 PF00036.30 MSTRG.31470.1_2 - 0.037 13.4 0.0 1.6 8.3 0.0 3.0 3 0 0 3 3 3 0 EF hand BTG PF07742.10 MSTRG.52513.1_3 - 1.5e-05 24.7 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 BTG family LRRNT PF01462.16 MSTRG.124768.1_1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Ldl_recept_a PF00057.16 MSTRG.142750.1_1 - 3.4e-111 363.0 216.9 2e-13 50.2 6.8 13.4 13 0 0 13 13 13 11 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.15 MSTRG.142750.1_1 - 3.3e-65 216.2 19.3 1.6e-14 53.9 0.1 9.2 8 1 0 8 8 8 8 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.4 MSTRG.142750.1_1 - 4.4e-11 42.8 10.5 4.4e-11 42.8 10.5 9.3 6 4 1 7 7 7 4 Coagulation Factor Xa inhibitory site DUF5050 PF16472.3 MSTRG.142750.1_1 - 2.3e-09 36.8 0.2 1.7e-06 27.4 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF5050) SGL PF08450.10 MSTRG.142750.1_1 - 0.00012 21.6 6.6 2.1 7.7 0.2 5.4 4 2 1 5 5 5 2 SMP-30/Gluconolaconase/LRE-like region cEGF PF12662.5 MSTRG.142750.1_1 - 0.00013 21.7 1.4 0.00013 21.7 1.4 7.1 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF PF00008.25 MSTRG.142750.1_1 - 0.0047 17.1 22.4 0.0089 16.2 7.4 16.6 16 4 3 19 19 19 3 EGF-like domain NHL PF01436.19 MSTRG.142750.1_1 - 0.026 14.4 3.0 5.5 7.1 0.0 5.4 6 0 0 6 6 6 0 NHL repeat Filament PF00038.19 MSTRG.35881.1_2 - 0.0069 15.9 17.9 0.0069 15.9 17.9 3.3 1 1 2 3 3 3 2 Intermediate filament protein FPP PF05911.9 MSTRG.35881.1_2 - 0.02 13.1 43.4 0.058 11.5 42.5 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil GAS PF13851.4 MSTRG.35881.1_2 - 0.02 14.1 46.7 0.52 9.5 9.5 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.10 MSTRG.35881.1_2 - 0.057 13.4 51.0 0.033 14.1 20.9 4.4 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein DUF4686 PF15742.3 MSTRG.35881.1_2 - 0.25 10.3 52.8 0.11 11.5 41.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) YqgF PF14639.4 MSTRG.35881.1_2 - 0.93 9.1 8.5 1.6 8.4 0.2 2.8 2 1 0 3 3 3 0 Holliday-junction resolvase-like of SPT6 IncA PF04156.12 MSTRG.35881.1_2 - 1.9 8.1 51.3 72 2.9 41.3 3.3 1 1 1 2 2 2 0 IncA protein ATG16 PF08614.9 MSTRG.35881.1_2 - 3.7 7.5 48.2 0.068 13.2 32.1 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.9 MSTRG.35881.1_2 - 4.1 6.1 44.8 41 2.8 13.9 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.9 MSTRG.35881.1_2 - 4.3 7.5 17.8 1.7 8.8 0.2 4.1 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) SHE3 PF17078.3 MSTRG.35881.1_2 - 4.3 6.8 40.4 1.9 8.0 11.1 2.8 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Ax_dynein_light PF10211.7 MSTRG.35881.1_2 - 4.9 6.9 47.2 1.2 8.9 15.4 4.3 1 1 4 5 5 5 0 Axonemal dynein light chain zf-Di19 PF05605.10 MSTRG.66419.1_3 - 1.3e-14 54.1 5.0 1.7e-14 53.7 5.0 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.4 MSTRG.66419.1_3 - 0.077 13.7 5.6 0.56 11.1 2.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.4 MSTRG.66419.1_3 - 1.2 8.6 7.9 8 5.9 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.5 MSTRG.66419.1_3 - 2.5 8.0 9.1 3.2 7.7 0.6 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain EF-hand_1 PF00036.30 MSTRG.34315.1_1 - 5.4e-05 22.3 0.1 0.0035 16.7 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.4 MSTRG.34315.1_1 - 9.3e-05 22.7 0.0 0.00022 21.5 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.4 MSTRG.34315.1_1 - 0.00032 20.0 0.2 0.014 14.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.4 MSTRG.34315.1_1 - 0.00079 19.0 0.4 0.24 11.3 0.0 2.8 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.4 MSTRG.34315.1_1 - 0.0056 16.3 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair PKK PF12474.6 MSTRG.45220.1_2 - 0.00011 22.2 38.6 0.00011 22.2 38.6 4.3 1 1 2 4 4 4 2 Polo kinase kinase BLOC1S3 PF15753.3 MSTRG.20118.1_1 - 0.0066 16.5 1.1 0.0073 16.3 1.1 1.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 zf-C2H2 PF00096.24 MSTRG.89099.1_1 - 2e-17 62.4 19.8 0.00024 21.3 0.2 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.89099.1_1 - 8.2e-14 51.0 19.5 0.0053 17.3 0.2 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.4 MSTRG.89099.1_1 - 1.4e-10 41.0 22.6 8.2e-07 29.1 0.5 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.6 MSTRG.89099.1_1 - 1.1e-08 35.1 8.3 0.087 13.0 0.5 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 MSTRG.89099.1_1 - 5.9e-06 26.3 14.9 0.00069 19.8 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 MSTRG.89099.1_1 - 7.7e-05 22.2 13.4 0.034 13.8 0.1 4.2 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-LYAR PF08790.9 MSTRG.89099.1_1 - 0.002 17.9 1.0 0.0047 16.7 0.1 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Rpr2 PF04032.14 MSTRG.89099.1_1 - 0.0022 18.2 6.9 0.069 13.4 0.5 2.4 2 0 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2HE PF16278.3 MSTRG.89099.1_1 - 0.0032 17.8 18.5 0.0073 16.6 0.8 4.0 1 1 3 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.10 MSTRG.89099.1_1 - 0.0041 17.2 14.0 0.0045 17.1 1.1 2.9 1 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.5 MSTRG.89099.1_1 - 0.0046 17.1 12.7 4.3 7.6 0.2 3.4 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-Mss51 PF13824.4 MSTRG.89099.1_1 - 0.034 14.1 15.6 0.33 11.0 1.3 3.5 1 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_15 PF17032.3 MSTRG.89099.1_1 - 0.035 14.7 8.1 0.46 11.1 1.3 2.3 1 1 1 2 2 2 0 zinc-ribbon family HypA PF01155.17 MSTRG.89099.1_1 - 0.044 13.7 9.6 0.62 10.0 0.1 2.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.8 MSTRG.89099.1_1 - 0.092 12.8 11.0 5.4 7.1 2.7 3.6 3 1 0 3 3 3 0 Zinc ribbon domain SprT-like PF10263.7 MSTRG.89099.1_1 - 0.18 11.5 11.3 45 3.7 11.2 2.6 1 1 1 2 2 2 0 SprT-like family FYVE PF01363.19 MSTRG.89099.1_1 - 0.37 10.8 11.1 1.9 8.6 1.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger CpXC PF14353.4 MSTRG.89099.1_1 - 0.51 10.3 14.3 5.8 6.8 3.3 3.9 1 1 3 4 4 4 0 CpXC protein zf-C2HC_2 PF13913.4 MSTRG.89099.1_1 - 0.51 10.2 13.4 1.8 8.4 0.5 3.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type OrfB_Zn_ribbon PF07282.9 MSTRG.89099.1_1 - 0.53 10.1 13.2 1.1 9.1 0.5 3.2 1 1 2 3 3 3 0 Putative transposase DNA-binding domain PHD PF00628.27 MSTRG.89099.1_1 - 0.99 9.2 10.1 0.64 9.8 2.6 3.2 3 0 0 3 3 3 0 PHD-finger Zn_Tnp_IS1595 PF12760.5 MSTRG.89099.1_1 - 1 9.3 15.6 0.48 10.3 1.1 3.2 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Vps36-NZF-N PF16988.3 MSTRG.89099.1_1 - 1.4 8.2 0.0 1.4 8.2 0.0 2.7 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain C1_4 PF07975.10 MSTRG.89099.1_1 - 2.6 8.3 9.9 0.5 10.5 0.9 2.8 1 1 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_9 PF16293.3 MSTRG.89099.1_1 - 3 7.6 5.6 3.5 7.4 0.2 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Fer4_9 PF13187.4 MSTRG.89099.1_1 - 5.3 7.2 9.3 2.9 8.0 1.9 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain XPA_N PF01286.16 MSTRG.89099.1_1 - 5.3 7.0 10.8 17 5.4 0.1 3.7 4 0 0 4 4 4 0 XPA protein N-terminal zf-RRN7 PF11781.6 MSTRG.89099.1_1 - 8.3 6.1 9.2 14 5.3 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.4 MSTRG.89099.1_1 - 8.3 6.3 12.5 27 4.6 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain C1_2 PF03107.14 MSTRG.89099.1_1 - 9.3 6.5 14.8 23 5.3 4.0 3.9 2 1 1 3 3 3 0 C1 domain NCA2 PF08637.8 MSTRG.89099.1_2 - 0.055 12.5 0.0 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 RETICULATA-like PF11891.6 MSTRG.49724.1_2 - 0.049 13.3 0.0 0.059 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein RETICULATA-related Adenylsucc_synt PF00709.19 MSTRG.75483.1_1 - 9.1e-29 100.5 0.2 9.6e-29 100.4 0.2 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF4426 PF14467.4 MSTRG.107564.1_2 - 0.096 12.6 1.6 0.16 11.9 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) BUD22 PF09073.8 MSTRG.107564.1_2 - 4.1 6.5 19.3 5.1 6.2 19.3 1.0 1 0 0 1 1 1 0 BUD22 DUF3332 PF11810.6 MSTRG.107564.1_2 - 4.6 6.7 6.8 6.1 6.3 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) HTH_29 PF13551.4 MSTRG.73014.1_3 - 3.2e-05 23.7 1.0 3.2e-05 23.7 1.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.4 MSTRG.73014.1_3 - 0.0068 16.4 1.5 0.015 15.3 1.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.4 MSTRG.73014.1_3 - 0.0095 16.4 9.6 0.15 12.6 7.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.13 MSTRG.73014.1_3 - 0.061 13.3 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase ASD1 PF08688.8 MSTRG.73014.1_3 - 0.071 13.3 0.2 0.1 12.8 0.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 PSD5 PF07637.9 MSTRG.73014.1_3 - 8.2 6.7 7.6 54 4.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1595) GFO_IDH_MocA PF01408.20 MSTRG.90229.1_2 - 0.046 14.4 0.0 0.052 14.2 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.17 MSTRG.90229.1_2 - 0.064 13.8 0.0 0.073 13.6 0.0 1.1 1 0 0 1 1 1 0 CoA binding domain NPV_P10 PF05531.10 MSTRG.77481.1_2 - 0.0061 16.9 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Not3 PF04065.13 MSTRG.77481.1_2 - 0.039 13.3 0.8 0.055 12.8 0.8 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF4724 PF15852.3 MSTRG.77481.1_2 - 0.053 13.7 0.1 0.084 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) Syntaxin-6_N PF09177.9 MSTRG.77481.1_2 - 0.059 13.8 0.5 0.098 13.1 0.5 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1891 PF09004.8 MSTRG.77481.1_3 - 0.024 14.1 0.3 0.043 13.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Alg6_Alg8 PF03155.13 MSTRG.140944.1_1 - 5.2e-07 29.0 0.4 6.2e-07 28.7 0.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TMEM239 PF15841.3 MSTRG.140944.1_1 - 0.063 13.0 0.5 0.069 12.9 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 239 family MVP_shoulder PF11978.6 MSTRG.91784.1_3 - 6.8e-52 174.3 0.1 1.1e-51 173.7 0.1 1.3 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.16 MSTRG.91784.1_3 - 4.9e-09 36.2 1.4 3.8e-08 33.3 1.9 2.1 2 0 0 2 2 2 1 Major Vault Protein repeat C1q PF00386.19 MSTRG.69620.3_1 - 4e-14 52.8 0.5 7.5e-14 51.9 0.4 1.5 1 1 0 1 1 1 1 C1q domain TMIE PF16038.3 MSTRG.69620.3_1 - 0.06 13.1 0.1 0.097 12.4 0.1 1.3 1 0 0 1 1 1 0 TMIE protein WXG100 PF06013.10 MSTRG.69620.3_1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG zf-C2H2 PF00096.24 MSTRG.66355.1_1 - 6.6e-12 45.1 10.5 1.5e-05 25.0 1.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.66355.1_1 - 3.5e-07 30.2 2.0 3.5e-07 30.2 2.0 2.7 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.66355.1_1 - 2.6e-06 27.6 9.2 0.01 16.5 1.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.66355.1_1 - 5.6e-06 26.4 12.4 0.001 19.2 2.2 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.4 MSTRG.66355.1_1 - 9.4e-06 25.2 9.0 0.00092 18.8 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-met PF12874.5 MSTRG.66355.1_1 - 7.5e-05 22.8 10.1 0.043 14.1 2.9 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type NOA36 PF06524.10 MSTRG.66355.1_1 - 0.0019 17.5 11.4 0.0019 17.5 11.4 1.4 2 0 0 2 2 2 1 NOA36 protein Svf1_C PF17187.2 MSTRG.66355.1_1 - 0.032 13.9 0.1 0.087 12.5 0.0 1.7 2 0 0 2 2 2 0 Svf1-like C-terminal lipocalin-like domain Vps36-NZF-N PF16988.3 MSTRG.66355.1_1 - 0.061 12.6 1.9 2.3 7.5 0.0 2.5 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_2 PF12756.5 MSTRG.66355.1_1 - 0.078 13.2 10.8 0.25 11.6 8.4 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) A2L_zn_ribbon PF08792.8 MSTRG.66355.1_1 - 0.44 10.2 2.7 6.6 6.4 0.4 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain GATA PF00320.25 MSTRG.66355.1_1 - 0.84 9.2 3.7 2.6 7.6 1.1 2.5 2 0 0 2 2 2 0 GATA zinc finger Rpr2 PF04032.14 MSTRG.66355.1_1 - 0.93 9.8 4.5 5.4 7.3 1.8 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_S13_N PF08069.10 MSTRG.4991.1_1 - 0.055 13.4 0.9 6.3 6.8 0.1 2.5 1 1 1 2 2 2 0 Ribosomal S13/S15 N-terminal domain Exo_endo_phos_2 PF14529.4 MSTRG.85325.1_3 - 0.0041 16.8 0.1 0.024 14.3 0.0 2.1 1 1 0 2 2 2 1 Endonuclease-reverse transcriptase C2 PF00168.28 MSTRG.141073.1_1 - 6.1e-15 55.2 0.3 3.4e-12 46.4 0.3 2.0 1 1 0 1 1 1 1 C2 domain Nucleoporin_FG2 PF15967.3 MSTRG.110664.1_3 - 0.052 11.9 0.9 0.057 11.8 0.9 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region HTH_23 PF13384.4 MSTRG.57710.1_2 - 0.0014 18.2 0.1 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.4 MSTRG.57710.1_2 - 0.014 15.0 0.3 0.025 14.2 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.13 MSTRG.57710.1_2 - 0.023 14.7 0.2 0.023 14.7 0.2 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Lung_7-TM_R PF06814.11 MSTRG.137559.1_2 - 8.2e-15 54.6 2.6 8.8e-15 54.5 2.6 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor E2 PF08199.9 MSTRG.138325.1_1 - 0.11 12.4 0.4 0.2 11.5 0.4 1.4 1 0 0 1 1 1 0 Bacteriophage E2-like protein Defensin_2 PF01097.16 MSTRG.18171.1_3 - 3.9 7.3 12.0 0.59 10.0 3.2 2.7 1 1 1 2 2 2 0 Arthropod defensin PerB PF06590.9 MSTRG.40409.1_1 - 0.15 12.4 0.2 0.18 12.2 0.2 1.1 1 0 0 1 1 1 0 PerB protein RRM_1 PF00076.20 MSTRG.11475.1_3 - 1.5e-24 85.4 0.0 6.5e-19 67.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 MSTRG.11475.1_3 - 0.00027 20.9 1.8 0.77 9.8 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif RVT_1 PF00078.25 MSTRG.3663.1_1 - 4.1e-39 134.3 0.0 4.6e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WAC_Acf1_DNA_bd PF10537.7 MSTRG.23120.1_2 - 4.3e-31 107.3 0.0 4.3e-31 107.3 0.0 2.6 2 1 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal CDC45 PF02724.12 MSTRG.23120.1_2 - 0.18 9.9 10.7 0.29 9.3 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.6 MSTRG.23120.1_2 - 7 5.2 9.5 12 4.5 9.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter PDCD9 PF07147.10 MSTRG.43609.1_3 - 4.6e-171 569.8 0.1 5.2e-171 569.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) muHD PF10291.7 MSTRG.97512.1_1 - 0.038 13.3 0.0 0.041 13.2 0.0 1.0 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain HTH_38 PF13936.4 MSTRG.89605.1_3 - 0.00031 20.3 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.89605.1_3 - 0.00043 19.9 0.0 0.00055 19.5 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.4 MSTRG.89605.1_3 - 0.037 14.0 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Bot1p PF12298.6 MSTRG.89605.1_3 - 0.056 13.5 0.0 0.066 13.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Ribosomal_S13_N PF08069.10 MSTRG.89605.1_3 - 0.096 12.6 0.4 1.6 8.7 0.1 2.2 1 1 1 2 2 2 0 Ribosomal S13/S15 N-terminal domain Reticulon PF02453.15 MSTRG.87311.1_2 - 4.6e-47 159.7 4.6 4.6e-47 159.7 4.6 1.9 3 0 0 3 3 3 1 Reticulon Myc_target_1 PF15179.4 MSTRG.125643.1_1 - 0.5 10.1 3.4 9.6 5.9 0.7 2.1 1 1 1 2 2 2 0 Myc target protein 1 Myc_target_1 PF15179.4 MSTRG.125643.1_2 - 0.11 12.2 4.8 1.2 8.9 0.9 2.5 1 1 1 2 2 2 0 Myc target protein 1 HHH_4 PF14490.4 MSTRG.125643.1_3 - 0.051 13.4 1.6 9.4 6.2 0.1 2.7 1 1 2 3 3 3 0 Helix-hairpin-helix containing domain SPRY PF00622.26 MSTRG.74250.1_3 - 4.2e-17 62.2 0.0 7.6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain PRY PF13765.4 MSTRG.74250.1_3 - 1.2e-12 47.1 0.0 2.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 SPRY-associated domain zf-B_box PF00643.22 MSTRG.74250.1_3 - 2.9e-07 30.4 8.1 2.9e-07 30.4 8.1 2.4 2 0 0 2 2 2 1 B-box zinc finger ApoLp-III PF07464.9 MSTRG.74250.1_3 - 0.67 9.9 6.0 8.4 6.3 5.0 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF342 PF03961.11 MSTRG.74250.1_3 - 2.1 6.7 8.3 1.3 7.4 5.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) KxDL PF10241.7 MSTRG.74250.1_3 - 2.8 8.2 13.9 1.5 9.0 2.3 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein TMPIT PF07851.11 MSTRG.74250.1_3 - 5 6.1 9.4 16 4.5 9.4 1.8 1 1 0 1 1 1 0 TMPIT-like protein Syntaxin-6_N PF09177.9 MSTRG.74250.1_3 - 6.5 7.3 9.0 2.7 8.5 3.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal MCU PF04678.11 MSTRG.74250.1_3 - 8 6.4 11.8 10 6.1 8.4 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Ufm1 PF03671.12 MSTRG.35362.1_2 - 0.12 12.3 0.4 91 3.1 0.0 2.9 1 1 2 3 3 3 0 Ubiquitin fold modifier 1 protein TP1 PF02079.14 MSTRG.35362.1_2 - 1.1 9.0 9.5 37 4.2 0.6 4.6 1 1 4 5 5 5 0 Nuclear transition protein 1 Toxin_33 PF08121.9 MSTRG.35362.1_3 - 0.0011 18.6 3.6 1.5e+02 2.2 0.0 5.7 6 0 0 6 6 6 0 Waglerin family Pea-VEAacid PF08111.9 MSTRG.35362.1_3 - 0.0042 17.1 1.2 3.7e+02 1.7 0.0 5.5 6 0 0 6 6 6 0 Pea-VEAacid family Alpha_E3_glycop PF01563.14 MSTRG.35362.1_3 - 0.088 12.8 0.8 22 5.1 0.1 2.9 1 1 2 3 3 3 0 Alphavirus E3 glycoprotein dsrm PF00035.24 MSTRG.124004.1_3 - 0.00014 22.3 0.5 0.00024 21.6 0.5 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif FliG_M PF14841.4 MSTRG.49301.1_1 - 0.00017 21.6 3.4 1.5 9.0 0.1 3.6 1 1 2 4 4 4 4 FliG middle domain TMEM239 PF15841.3 MSTRG.49301.1_1 - 2.4 7.8 6.6 7 6.3 6.6 1.7 1 1 0 1 1 1 0 Transmembrane protein 239 family DDE_Tnp_IS1 PF03400.11 MSTRG.49301.1_1 - 6.3 7.0 10.6 26 5.0 2.3 2.7 1 1 2 3 3 3 0 IS1 transposase FNIP PF05725.10 MSTRG.49301.1_2 - 2.2 8.4 20.7 29 4.8 0.2 6.2 1 1 6 7 7 7 0 FNIP Repeat Saf-Nte_pilin PF09460.8 MSTRG.49301.1_2 - 2.3 8.1 6.7 4.6 7.1 0.2 2.7 1 1 1 3 3 3 0 Saf-pilin pilus formation protein Cohesin_HEAT PF12765.5 MSTRG.49301.1_3 - 0.081 13.0 0.3 87 3.3 0.0 4.1 2 2 3 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.20 MSTRG.140756.1_3 - 4.5e-08 32.5 1.1 0.018 15.1 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.5 MSTRG.140756.1_3 - 0.036 13.9 1.8 0.33 10.8 0.6 2.6 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.4 MSTRG.140756.1_3 - 0.081 13.2 0.0 0.6 10.4 0.0 2.3 1 1 1 2 2 2 0 HEAT repeats AflR PF08493.8 MSTRG.95793.1_2 - 1.2 8.4 14.6 1.2 8.4 14.6 1.0 1 0 0 1 1 1 0 Aflatoxin regulatory protein Med3 PF11593.6 MSTRG.95793.1_2 - 3.3 6.7 10.1 3.5 6.6 10.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Gelsolin PF00626.20 MSTRG.25917.1_1 - 2.8e-12 46.2 0.0 3.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Gelsolin repeat DDE_3 PF13358.4 MSTRG.105201.1_1 - 1.1e-09 38.1 0.1 1.1e-09 38.1 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Ldl_recept_b PF00058.15 MSTRG.16933.2_2 - 3e-51 171.5 3.5 9.6e-14 51.5 0.2 5.5 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.4 MSTRG.16933.2_2 - 6.6e-13 48.6 19.9 3.4e-07 30.3 4.9 2.8 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.13 MSTRG.16933.2_2 - 5e-09 36.1 7.5 5e-09 36.1 7.5 2.4 3 0 0 3 3 3 1 Calcium-binding EGF domain SGL PF08450.10 MSTRG.16933.2_2 - 2.8e-05 23.7 1.7 0.025 14.0 0.2 2.6 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region DUF5050 PF16472.3 MSTRG.16933.2_2 - 0.00032 19.9 0.0 0.0008 18.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5050) cEGF PF12662.5 MSTRG.16933.2_2 - 0.00086 19.1 1.3 0.00086 19.1 1.3 3.2 3 0 0 3 3 3 1 Complement Clr-like EGF-like TMEM154 PF15102.4 MSTRG.16933.2_2 - 0.03 14.1 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family EGF PF00008.25 MSTRG.16933.2_2 - 0.068 13.4 13.8 0.026 14.7 4.4 2.8 2 0 0 2 2 2 0 EGF-like domain Gemini_mov PF01708.14 MSTRG.16933.2_2 - 0.097 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein hEGF PF12661.5 MSTRG.16933.2_2 - 0.14 12.8 7.6 0.11 13.0 2.4 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_3 PF12947.5 MSTRG.16933.2_2 - 0.29 11.2 9.2 0.15 12.1 2.8 2.7 2 0 0 2 2 2 0 EGF domain RVT_1 PF00078.25 MSTRG.65630.1_2 - 5.5e-08 32.5 0.0 6.6e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LUC7 PF03194.13 MSTRG.83648.3_1 - 3.9e-83 278.7 25.4 3.9e-83 278.7 25.4 2.9 1 1 1 2 2 2 1 LUC7 N_terminus MIP-T3 PF10243.7 MSTRG.83648.3_1 - 9.3e-06 24.5 72.6 1.5e-05 23.8 72.6 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF2680 PF10925.6 MSTRG.81254.1_2 - 0.031 14.1 0.4 26 4.8 0.0 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF2680) DUF2399 PF09664.8 MSTRG.81254.1_2 - 0.19 11.5 1.2 2.5 7.9 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2399) FSAP_sig_propep PF03032.13 MSTRG.81254.1_3 - 1.3 8.9 18.0 3.9 7.5 0.8 4.1 4 0 0 4 4 4 0 Frog skin active peptide family signal and propeptide RVT_1 PF00078.25 MSTRG.110978.1_3 - 4.5e-14 52.4 0.0 5e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) XLF PF09302.9 MSTRG.110978.1_3 - 0.11 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component SSV1_ORF_D-335 PF07935.9 MSTRG.12881.1_3 - 0.026 14.7 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 ORF D-335-like protein Rho_Binding PF08912.9 MSTRG.117218.1_2 - 2.7e-25 88.8 15.7 2.7e-25 88.8 15.7 9.4 3 1 7 10 10 10 1 Rho Binding CENP-F_leu_zip PF10473.7 MSTRG.117218.1_2 - 0.0086 16.0 9.2 0.0086 16.0 9.2 6.9 1 1 5 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.10 MSTRG.117218.1_2 - 2.1 7.6 27.8 0.59 9.3 6.7 3.7 1 1 3 4 4 4 0 Reovirus sigma C capsid protein p450 PF00067.20 MSTRG.40531.1_1 - 8.9e-97 324.6 0.0 1.1e-96 324.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_29 PF13551.4 MSTRG.133525.1_1 - 0.00072 19.4 0.3 0.031 14.2 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.4 MSTRG.133525.1_1 - 0.0017 18.0 0.1 0.003 17.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.133525.1_1 - 0.01 15.5 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.133525.1_1 - 0.012 16.1 0.1 0.046 14.2 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Pkinase PF00069.23 MSTRG.136779.1_2 - 2.2e-18 66.4 0.0 2.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.136779.1_2 - 1.3e-06 27.8 0.0 1.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 MSTRG.136779.1_2 - 0.035 13.3 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like I-set PF07679.14 MSTRG.66461.1_1 - 7.9e-11 41.8 0.0 9.8e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.66461.1_1 - 7.6e-08 32.7 0.0 1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.66461.1_1 - 4.8e-05 23.3 0.2 6.6e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.66461.1_1 - 0.00024 21.2 0.0 0.00027 21.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 MSTRG.66461.1_1 - 0.00079 19.4 0.1 0.8 9.8 0.0 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain Izumo-Ig PF16706.3 MSTRG.66461.1_1 - 0.0031 17.4 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain HOOK PF05622.10 MSTRG.29633.1_2 - 5.2e-82 276.0 7.0 5.7e-82 275.9 7.0 1.0 1 0 0 1 1 1 1 HOOK protein W2 PF02020.16 MSTRG.131165.1_3 - 1.7e-15 56.8 0.7 2.4e-15 56.3 0.7 1.2 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon ACDC PF14733.4 MSTRG.95531.1_1 - 0.012 15.7 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 AP2-coincident C-terminal HTH_Tnp_Tc3_2 PF01498.16 MSTRG.141518.1_1 - 3.5e-12 46.2 1.0 5.5e-12 45.6 1.0 1.3 1 0 0 1 1 1 1 Transposase Filament PF00038.19 MSTRG.52242.1_2 - 3.6e-77 259.9 20.0 2.9e-58 197.8 8.5 2.1 1 1 1 2 2 2 2 Intermediate filament protein PilO PF04350.11 MSTRG.52242.1_2 - 0.016 15.2 0.4 0.17 11.9 0.1 2.6 2 1 1 3 3 3 0 Pilus assembly protein, PilO TPR_MLP1_2 PF07926.10 MSTRG.52242.1_2 - 0.018 15.0 0.6 0.018 15.0 0.6 4.0 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.10 MSTRG.52242.1_2 - 0.02 14.8 8.6 0.6 10.0 1.5 3.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SPATA1_C PF15743.3 MSTRG.52242.1_2 - 0.027 14.4 10.4 0.028 14.4 1.0 3.1 2 1 0 3 3 3 0 Spermatogenesis-associated C-terminus ADIP PF11559.6 MSTRG.52242.1_2 - 0.047 13.6 9.5 0.73 9.8 0.1 3.3 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.7 MSTRG.52242.1_2 - 0.11 10.9 4.6 0.091 11.2 2.1 1.7 1 1 1 2 2 2 0 Transmembrane protein IncA PF04156.12 MSTRG.52242.1_2 - 0.21 11.2 10.8 10 5.7 1.2 3.1 2 1 0 3 3 3 0 IncA protein Cep57_MT_bd PF06657.11 MSTRG.52242.1_2 - 0.34 11.3 10.0 12 6.2 0.5 3.6 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Apolipoprotein PF01442.16 MSTRG.52242.1_2 - 0.36 10.6 15.7 1 9.1 10.6 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF972 PF06156.11 MSTRG.52242.1_2 - 0.69 10.4 10.7 1.3 9.5 0.1 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF972) Muted PF14942.4 MSTRG.52242.1_2 - 1.7 8.8 7.4 12 6.1 0.2 2.7 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Fez1 PF06818.13 MSTRG.52242.1_2 - 2.6 8.3 10.7 7 6.9 0.8 2.7 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.4 MSTRG.52242.1_2 - 5.6 6.1 8.7 80 2.3 8.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Lipoprotein_20 PF13942.4 MSTRG.52242.1_2 - 5.6 6.7 7.5 0.4 10.5 0.6 2.4 2 1 0 3 3 3 0 YfhG lipoprotein KxDL PF10241.7 MSTRG.52242.1_2 - 7.1 6.8 9.1 3.8 7.7 0.1 4.0 3 1 1 4 4 4 0 Uncharacterized conserved protein Cadherin_C_2 PF16492.3 MSTRG.12807.2_3 - 0.095 13.4 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal FATC PF02260.18 MSTRG.144033.1_2 - 0.0017 18.0 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 FATC domain Lzipper-MIP1 PF14389.4 MSTRG.144033.1_2 - 0.0031 17.6 10.6 0.22 11.7 4.4 2.2 1 1 1 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 TPR_2 PF07719.15 MSTRG.144033.1_2 - 0.15 12.1 1.0 0.33 11.0 0.4 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat MDM10 PF12519.6 MSTRG.144033.1_2 - 0.21 10.3 3.9 0.22 10.2 3.9 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Macoilin PF09726.7 MSTRG.144033.1_2 - 0.61 8.4 12.8 0.7 8.2 12.8 1.2 1 0 0 1 1 1 0 Transmembrane protein MMS1_N PF10433.7 MSTRG.104267.1_3 - 4.1e-10 38.7 0.0 4.7e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Granulin PF00396.16 MSTRG.64424.1_3 - 6.7e-14 51.8 23.8 1.5e-13 50.7 19.8 2.2 2 0 0 2 2 2 1 Granulin Prenyltrans PF00432.19 MSTRG.64424.1_3 - 0.0045 16.6 9.0 0.31 10.7 0.1 2.9 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat STAT1_TAZ2bind PF12162.6 MSTRG.98297.1_2 - 0.13 11.8 0.2 0.22 11.0 0.2 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Neur_chan_LBD PF02931.21 MSTRG.143213.1_1 - 1.4e-06 27.8 0.4 1.7e-06 27.5 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ESSS PF10183.7 MSTRG.143358.1_3 - 2.1e-39 133.8 0.0 2.6e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Tetraspannin PF00335.18 MSTRG.69500.1_1 - 1.6e-05 24.7 6.5 2e-05 24.4 6.5 1.1 1 0 0 1 1 1 1 Tetraspanin family RVT_1 PF00078.25 MSTRG.102241.1_2 - 1.1e-18 67.4 0.0 1.4e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dynactin PF12455.6 MSTRG.39895.1_3 - 9.6e-28 97.1 0.0 1e-27 97.0 0.0 1.0 1 0 0 1 1 1 1 Dynein associated protein Rhodanese PF00581.18 MSTRG.24394.1_3 - 1e-12 48.3 0.0 1.3e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF1816 PF08846.8 MSTRG.38213.1_3 - 0.05 13.5 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) API5 PF05918.9 MSTRG.111106.1_1 - 6 5.4 5.8 7.3 5.1 5.8 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TFIIF_alpha PF05793.10 MSTRG.111106.1_3 - 0.2 10.1 22.0 0.21 10.0 22.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.7 MSTRG.111106.1_3 - 0.38 9.3 22.7 0.43 9.1 22.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Baculo_PP31 PF05311.9 MSTRG.111106.1_3 - 1.2 8.4 12.5 1.3 8.3 12.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FLO_LFY PF01698.14 MSTRG.111106.1_3 - 2.9 6.9 12.3 3.4 6.7 12.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Med19 PF10278.7 MSTRG.111106.1_3 - 3.4 7.4 24.4 4.1 7.2 24.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.12 MSTRG.111106.1_3 - 4.9 5.2 18.8 5.5 5.0 18.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.9 MSTRG.111106.1_3 - 5.6 6.9 23.9 6.9 6.6 23.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Rrn6 PF10214.7 MSTRG.111106.1_3 - 8.2 4.6 14.4 9 4.4 14.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NARP1 PF12569.6 MSTRG.111106.1_3 - 8.2 5.0 19.2 8.9 4.9 19.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MAP17 PF15807.3 MSTRG.111106.1_3 - 8.9 6.4 9.3 11 6.0 9.3 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HTH_Tnp_Tc3_2 PF01498.16 MSTRG.99371.1_1 - 0.011 15.9 0.7 0.011 15.9 0.7 1.6 2 0 0 2 2 2 0 Transposase HTH_32 PF13565.4 MSTRG.99371.1_3 - 0.0081 16.6 0.3 0.0097 16.4 0.3 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.9369.1_1 - 1.9e-07 31.1 0.4 2.6e-07 30.6 0.4 1.2 1 0 0 1 1 1 1 Transposase HTH_21 PF13276.4 MSTRG.9369.1_1 - 0.021 14.8 0.4 0.032 14.2 0.4 1.3 1 0 0 1 1 1 0 HTH-like domain DDE_Tnp_ISAZ013 PF07592.9 MSTRG.9369.1_1 - 0.068 12.0 0.2 0.074 11.9 0.2 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain KcnmB2_inactiv PF09303.8 MSTRG.9369.1_1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 KCNMB2, ball and chain domain DDE_3 PF13358.4 MSTRG.84622.1_1 - 2.1e-10 40.4 0.5 3.9e-10 39.5 0.2 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease Ligase_CoA PF00549.17 MSTRG.3873.1_2 - 8.5e-07 28.8 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 CoA-ligase HECT PF00632.23 MSTRG.55343.1_1 - 1.5e-92 310.2 0.4 1.9e-92 309.9 0.4 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) La PF05383.15 MSTRG.115353.1_1 - 6.9e-11 41.9 0.1 1.2e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 La domain FAM184 PF15665.3 MSTRG.26388.1_2 - 0.0062 16.2 7.4 0.0062 16.2 7.4 1.5 1 1 0 1 1 1 1 Family with sequence similarity 184, A and B Alpha-2-MRAP_C PF06401.9 MSTRG.26388.1_2 - 0.024 14.5 4.5 0.029 14.2 4.5 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF2383 PF09537.8 MSTRG.26388.1_2 - 0.043 14.1 1.4 0.062 13.5 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2383) TMF_TATA_bd PF12325.6 MSTRG.26388.1_2 - 0.055 13.6 9.3 0.1 12.7 9.3 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.10 MSTRG.26388.1_2 - 0.056 13.8 2.2 0.094 13.1 0.2 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.8 MSTRG.26388.1_2 - 0.07 13.3 7.6 0.3 11.3 1.4 2.9 1 1 2 3 3 3 0 Tup N-terminal TMPIT PF07851.11 MSTRG.26388.1_2 - 0.37 9.8 3.4 0.44 9.6 3.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein EPF PF17181.2 MSTRG.17746.1_2 - 0.034 14.0 0.8 0.053 13.4 0.8 1.2 1 0 0 1 1 1 0 Epidermal patterning factor proteins Glyco_hydro_47 PF01532.18 MSTRG.17746.1_3 - 6.1e-05 22.0 0.0 7.2e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Porin_3 PF01459.20 MSTRG.12658.1_1 - 7.5e-84 281.2 9.9 9.1e-84 281.0 9.9 1.1 1 0 0 1 1 1 1 Eukaryotic porin DUF1598 PF07643.9 MSTRG.84517.1_1 - 0.098 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) Trp_leader2 PF08056.9 MSTRG.41533.1_2 - 0.0072 16.1 3.9 0.015 15.1 3.9 1.5 1 0 0 1 1 1 1 Tryptophan operon leader peptide zf-SAP30 PF13866.4 MSTRG.41533.1_3 - 0.043 13.7 2.1 0.043 13.7 2.1 1.8 2 0 0 2 2 2 0 SAP30 zinc-finger CagZ PF09053.8 MSTRG.29963.1_1 - 0.025 14.1 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 CagZ PMP22_Claudin PF00822.18 MSTRG.58596.2_3 - 4.5e-27 94.8 9.8 6.5e-27 94.3 9.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Trp_oprn_chp PF09534.8 MSTRG.58596.2_3 - 1.4 8.6 5.5 2.9 7.5 1.4 2.6 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) IP_trans PF02121.16 MSTRG.93485.1_3 - 1.2e-46 159.2 0.4 1.4e-46 158.9 0.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.139123.1_3 - 0.042 14.0 0.4 0.1 12.8 0.4 1.7 1 1 0 1 1 1 0 Transposase DUF4071 PF13281.4 MSTRG.15619.1_3 - 1.2e-21 77.1 0.0 1.3e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) HIP1_clath_bdg PF16515.3 MSTRG.97483.1_2 - 0.00056 20.3 2.6 0.00067 20.1 1.9 1.5 1 1 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Cortex-I_coil PF09304.8 MSTRG.97483.1_2 - 0.0025 17.9 1.3 0.0089 16.1 0.5 1.8 1 1 1 2 2 2 1 Cortexillin I, coiled coil JIP_LZII PF16471.3 MSTRG.97483.1_2 - 0.015 15.3 0.7 0.023 14.7 0.7 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II betaPIX_CC PF16523.3 MSTRG.97483.1_2 - 0.019 14.6 1.8 0.02 14.6 1.0 1.4 1 1 1 2 2 2 0 betaPIX coiled coil Reo_sigmaC PF04582.10 MSTRG.97483.1_2 - 0.061 12.6 0.1 0.068 12.4 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TolA_bind_tri PF16331.3 MSTRG.97483.1_2 - 0.089 12.7 4.6 0.31 11.0 4.6 1.8 1 1 0 1 1 1 0 TolA binding protein trimerisation PDCD7 PF16021.3 MSTRG.70275.1_3 - 2e-113 378.5 23.8 3.1e-113 377.9 23.8 1.3 1 0 0 1 1 1 1 Programmed cell death protein 7 MFS_2 PF13347.4 MSTRG.97870.1_1 - 0.00022 19.8 0.0 0.00024 19.6 0.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Laminin_G_2 PF02210.22 MSTRG.41175.1_1 - 0.00021 21.8 0.0 0.00023 21.6 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.21 MSTRG.41175.1_1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain APOBEC_N PF08210.9 MSTRG.41175.1_3 - 0.13 12.1 3.8 0.14 12.0 3.8 1.0 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Ion_trans_2 PF07885.14 MSTRG.87398.1_2 - 1.2e-11 44.3 4.1 1.2e-11 44.3 4.1 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.29 MSTRG.87398.1_2 - 5e-11 42.2 0.5 5.3e-11 42.1 0.5 1.0 1 0 0 1 1 1 1 Ion transport protein BTP PF05232.10 MSTRG.87398.1_2 - 3.3 7.7 5.9 1.7e+02 2.2 5.9 2.1 1 1 0 1 1 1 0 Chlorhexidine efflux transporter zf-C2H2 PF00096.24 MSTRG.23670.2_1 - 5.1e-22 76.9 48.3 9.1e-06 25.7 3.3 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.23670.2_1 - 1.8e-18 65.9 45.9 5.7e-06 26.4 0.7 6.9 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.23670.2_1 - 1.6e-15 56.3 41.9 0.0021 18.6 1.9 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.23670.2_1 - 8.7e-09 35.0 34.9 0.00014 21.6 1.3 5.5 6 0 0 6 6 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.23670.2_1 - 1.2e-05 25.4 25.6 0.14 12.3 1.4 5.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding C1_4 PF07975.10 MSTRG.23670.2_1 - 6.6e-05 23.0 18.3 0.21 11.8 2.3 3.6 2 1 1 3 3 3 2 TFIIH C1-like domain Zn-ribbon_8 PF09723.8 MSTRG.23670.2_1 - 8.8e-05 22.4 18.8 0.091 12.8 1.4 3.5 3 0 0 3 3 3 2 Zinc ribbon domain GAGA PF09237.9 MSTRG.23670.2_1 - 0.0038 16.9 14.4 0.26 11.0 0.3 4.0 1 1 3 4 4 4 2 GAGA factor zf-met PF12874.5 MSTRG.23670.2_1 - 0.0078 16.4 32.1 0.041 14.1 1.1 5.0 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-AN1 PF01428.14 MSTRG.23670.2_1 - 0.0096 15.9 27.1 0.31 11.1 3.1 5.3 4 1 1 5 5 5 1 AN1-like Zinc finger zf-C2HC_2 PF13913.4 MSTRG.23670.2_1 - 0.018 14.8 1.4 0.018 14.8 1.4 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.12 MSTRG.23670.2_1 - 0.033 13.9 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF3268 PF11672.6 MSTRG.23670.2_1 - 0.19 12.0 8.8 0.62 10.3 0.6 2.5 1 1 0 2 2 2 0 zinc-finger-containing domain DUF4379 PF14311.4 MSTRG.23670.2_1 - 0.29 11.4 0.1 0.29 11.4 0.1 3.4 2 1 2 4 4 4 0 Probable Zinc-ribbon domain XPA_N PF01286.16 MSTRG.23670.2_1 - 0.29 11.1 15.2 0.69 9.9 0.8 5.1 5 0 0 5 5 5 0 XPA protein N-terminal FYVE PF01363.19 MSTRG.23670.2_1 - 0.81 9.7 25.8 1.2 9.2 5.0 3.4 1 1 2 3 3 3 0 FYVE zinc finger ADK_lid PF05191.12 MSTRG.23670.2_1 - 0.88 9.5 16.2 0.15 12.0 1.0 3.7 3 2 0 3 3 3 0 Adenylate kinase, active site lid DZR PF12773.5 MSTRG.23670.2_1 - 1.1 9.2 17.9 2.1e+03 -1.3 17.9 3.0 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.3 MSTRG.23670.2_1 - 2.2 8.9 15.6 1.1 9.9 1.3 3.1 1 1 3 4 4 4 0 zinc-ribbon family zf-H2C2_5 PF13909.4 MSTRG.23670.2_1 - 9.8 5.9 16.5 4.9 6.9 1.7 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HE PF16278.3 MSTRG.23670.2_1 - 10 6.6 28.0 0.13 12.6 2.4 4.7 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.17 MSTRG.23670.2_1 - 10 6.1 13.4 5.4 6.9 1.7 2.8 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pinin_SDK_memA PF04696.11 MSTRG.42501.1_2 - 2.1e-08 34.1 0.1 2.1e-08 34.1 0.1 2.1 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region Inhibitor_I67 PF11405.6 MSTRG.48122.1_2 - 0.061 13.5 0.1 0.095 12.8 0.1 1.2 1 0 0 1 1 1 0 Bromelain inhibitor VI Lectin_C PF00059.19 MSTRG.10444.1_3 - 3e-41 140.4 43.5 4.5e-18 65.8 10.8 5.0 4 1 1 5 5 5 3 Lectin C-type domain F5_F8_type_C PF00754.23 MSTRG.10444.1_3 - 8.5e-09 35.5 0.8 8.5e-09 35.5 0.8 2.8 1 1 0 2 2 2 1 F5/8 type C domain DUF3316 PF11777.6 MSTRG.10444.1_3 - 0.031 14.2 1.3 0.38 10.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) Xlink PF00193.15 MSTRG.10444.1_3 - 0.14 12.4 6.9 17 5.7 0.0 4.0 3 1 0 3 3 3 0 Extracellular link domain ECH_1 PF00378.18 MSTRG.85478.2_3 - 3.3e-17 62.5 0.0 4.3e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.3 MSTRG.85478.2_3 - 7.6e-05 22.2 0.0 9e-05 22.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HU-DNA_bdg PF14848.4 MSTRG.39377.1_3 - 0.041 13.7 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 DNA-binding domain I-set PF07679.14 MSTRG.86499.1_3 - 1.5e-18 66.5 3.6 1.1e-13 50.9 0.7 2.3 1 1 1 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.86499.1_3 - 5.4e-14 52.4 1.0 7.3e-11 42.4 0.3 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 MSTRG.86499.1_3 - 1.5e-11 44.2 2.8 2.7e-09 37.0 0.5 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.86499.1_3 - 1.2e-10 41.5 0.1 4e-08 33.3 0.1 2.2 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.15 MSTRG.86499.1_3 - 9.7e-06 25.6 0.8 0.013 15.5 0.2 3.1 2 1 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.13 MSTRG.86499.1_3 - 1.9e-05 24.9 0.9 0.012 15.9 0.2 2.4 2 1 0 2 2 2 2 Immunoglobulin C1-set domain Ig_5 PF16681.3 MSTRG.86499.1_3 - 0.00029 21.1 2.8 0.036 14.3 0.5 2.6 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.3 MSTRG.86499.1_3 - 0.0004 20.6 3.8 0.12 12.6 1.6 2.8 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.3 MSTRG.86499.1_3 - 0.00058 19.7 0.4 0.0011 18.9 0.2 1.6 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain ACAS_N PF16177.3 MSTRG.86499.1_3 - 0.0096 15.7 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 2 Acetyl-coenzyme A synthetase N-terminus DUF4662 PF15578.4 MSTRG.86499.1_3 - 0.019 14.6 2.2 0.021 14.4 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) C2-set_2 PF08205.10 MSTRG.86499.1_3 - 0.024 14.6 0.3 0.91 9.5 0.1 2.5 2 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain IL8 PF00048.18 MSTRG.116755.1_3 - 0.00063 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF3631 PF12307.6 MSTRG.116755.1_3 - 0.063 13.4 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) ADIP PF11559.6 MSTRG.46406.1_2 - 0.0028 17.6 5.8 0.0039 17.1 5.8 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding NB-LRR PF12061.6 MSTRG.46406.1_2 - 0.0033 16.2 0.3 0.0044 15.8 0.3 1.0 1 0 0 1 1 1 1 Late blight resistance protein R1 SesA PF17107.3 MSTRG.46406.1_2 - 0.0034 17.4 0.5 0.0066 16.5 0.5 1.6 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases YokU PF14122.4 MSTRG.46406.1_2 - 0.14 12.0 2.1 0.16 11.9 0.9 1.7 2 0 0 2 2 2 0 YokU-like protein, putative antitoxin DMPK_coil PF08826.8 MSTRG.46406.1_2 - 1.4 9.0 9.2 0.085 12.9 2.2 2.3 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF3496 PF12001.6 MSTRG.46406.1_2 - 1.9 8.8 8.0 2.4 8.4 1.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Kelch_1 PF01344.23 MSTRG.63042.1_1 - 2.7e-68 225.2 23.4 9.7e-20 69.8 0.5 5.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.4 MSTRG.63042.1_1 - 3.6e-36 122.1 5.6 2.3e-08 33.9 0.0 5.2 2 2 3 5 5 5 5 Kelch motif BACK PF07707.13 MSTRG.63042.1_1 - 2.5e-33 114.1 0.6 4.1e-33 113.4 0.6 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.13 MSTRG.63042.1_1 - 1.5e-31 107.0 5.5 2.5e-07 30.3 0.1 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.4 MSTRG.63042.1_1 - 5.1e-22 77.4 4.1 2e-06 27.5 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.4 MSTRG.63042.1_1 - 7e-19 67.5 12.7 4.4e-07 29.9 0.3 4.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.4 MSTRG.63042.1_1 - 2.9e-08 33.4 11.7 0.014 15.2 0.0 5.0 5 0 0 5 5 5 3 Kelch motif PQQ_3 PF13570.4 MSTRG.63042.1_1 - 1.8 9.0 8.9 6.7 7.2 0.0 3.7 5 0 0 5 5 5 0 PQQ-like domain OCIA PF07051.9 MSTRG.13653.1_3 - 0.02 14.7 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) CALCOCO1 PF07888.9 MSTRG.61043.1_1 - 1.2e-25 90.0 26.7 1.4e-25 89.9 26.7 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.12 MSTRG.61043.1_1 - 0.026 14.2 20.9 0.033 13.9 20.9 1.0 1 0 0 1 1 1 0 IncA protein Prefoldin PF02996.15 MSTRG.61043.1_1 - 0.028 14.2 1.8 0.028 14.2 1.8 2.5 2 1 0 2 2 2 0 Prefoldin subunit WD40_alt PF14077.4 MSTRG.61043.1_1 - 0.14 11.9 4.2 4.6 7.0 0.8 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif ATG16 PF08614.9 MSTRG.61043.1_1 - 0.18 11.9 23.0 0.26 11.3 23.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DASH_Dam1 PF08653.8 MSTRG.61043.1_1 - 0.34 10.6 1.5 1.7 8.4 0.3 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 AKNA PF12443.6 MSTRG.61043.1_1 - 0.36 11.4 7.3 0.18 12.3 3.7 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF2968 PF11180.6 MSTRG.61043.1_1 - 0.57 9.7 15.6 0.084 12.4 11.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) TBPIP PF07106.11 MSTRG.61043.1_1 - 0.98 9.0 16.7 1.6 8.3 16.7 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ERM PF00769.17 MSTRG.61043.1_1 - 1.1 8.9 30.6 1.2 8.8 30.6 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family RPW8 PF05659.9 MSTRG.61043.1_1 - 1.3 8.6 10.5 1.8 8.1 10.5 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Jnk-SapK_ap_N PF09744.7 MSTRG.61043.1_1 - 1.6 8.8 24.2 5.8 7.0 24.2 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.7 MSTRG.61043.1_1 - 1.9 7.7 21.6 2.4 7.4 21.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.11 MSTRG.61043.1_1 - 2.3 7.2 13.9 2.9 6.9 13.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein APG6 PF04111.10 MSTRG.61043.1_1 - 2.4 7.4 21.2 3 7.0 21.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.11 MSTRG.61043.1_1 - 2.6 6.4 13.4 3.2 6.1 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CCDC-167 PF15188.4 MSTRG.61043.1_1 - 3.4 7.9 19.9 6 7.2 19.6 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3552 PF12072.6 MSTRG.61043.1_1 - 3.5 6.9 28.4 4.2 6.6 28.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fib_alpha PF08702.8 MSTRG.61043.1_1 - 4.3 7.4 10.8 5.6 7.0 10.8 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.17 MSTRG.61043.1_1 - 8.7 4.0 11.6 10 3.7 11.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.7 MSTRG.61043.1_1 - 8.8 6.1 24.4 1.4 8.7 8.3 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain Integrin_alpha2 PF08441.10 MSTRG.114905.1_1 - 0.0002 20.2 0.0 0.00024 20.0 0.0 1.0 1 0 0 1 1 1 1 Integrin alpha EGF_CA PF07645.13 MSTRG.56914.1_3 - 3.9e-12 46.0 18.1 5.4e-10 39.2 7.7 2.2 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF PF00008.25 MSTRG.56914.1_3 - 3.5e-11 43.0 16.6 1.7e-05 24.9 3.7 2.5 2 0 0 2 2 2 2 EGF-like domain cEGF PF12662.5 MSTRG.56914.1_3 - 1.9e-08 33.9 7.8 4.6e-06 26.3 1.4 3.2 3 0 0 3 3 3 2 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.9 MSTRG.56914.1_3 - 2.2e-07 30.9 15.2 0.00043 20.4 2.8 2.4 2 0 0 2 2 2 2 Pvs28 EGF domain hEGF PF12661.5 MSTRG.56914.1_3 - 9.2e-07 29.2 21.5 6.6e-05 23.3 5.4 2.7 3 0 0 3 3 3 2 Human growth factor-like EGF FXa_inhibition PF14670.4 MSTRG.56914.1_3 - 1.5e-05 25.0 20.9 0.002 18.3 5.5 2.3 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_3 PF12947.5 MSTRG.56914.1_3 - 8.6e-05 22.5 13.6 0.028 14.5 4.2 2.4 2 0 0 2 2 2 2 EGF domain EGF_MSP1_1 PF12946.5 MSTRG.56914.1_3 - 0.017 15.1 5.8 0.017 15.1 5.8 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 EGF_2 PF07974.11 MSTRG.56914.1_3 - 0.085 13.1 20.1 0.087 13.1 7.3 2.4 2 0 0 2 2 2 0 EGF-like domain Mucin2_WxxW PF13330.4 MSTRG.21282.1_1 - 4.5e-09 36.9 0.1 7.5e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region Chal_sti_synt_C PF02797.13 MSTRG.21282.1_1 - 0.061 13.2 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Ets PF00178.20 MSTRG.95296.1_2 - 2.1e-29 101.7 2.3 3.5e-29 101.0 2.3 1.4 1 0 0 1 1 1 1 Ets-domain RAI16-like PF10257.7 MSTRG.87209.1_3 - 2.6e-41 141.6 0.6 4.2e-41 140.9 0.6 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein G-patch PF01585.21 MSTRG.112571.1_3 - 1.2e-18 66.5 3.6 3.3e-18 65.2 3.6 1.8 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.20 MSTRG.112571.1_3 - 2.6e-11 43.0 0.0 3.8e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.16 MSTRG.112571.1_3 - 3.1e-10 39.0 1.2 3.1e-10 39.0 1.2 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.5 MSTRG.112571.1_3 - 2e-09 37.2 2.7 9.5e-09 35.1 2.7 2.2 1 0 0 1 1 1 1 G-patch domain GSIII_N PF12437.6 MSTRG.112571.1_3 - 0.043 13.3 2.5 0.1 12.1 2.5 1.6 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal YL1_C PF08265.9 MSTRG.112571.1_3 - 0.97 9.1 3.8 7.3 6.3 3.8 2.4 1 1 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-C2H2_4 PF13894.4 MSTRG.112571.1_3 - 2.5 9.0 5.3 1 10.2 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Dynamin_N PF00350.21 MSTRG.91808.1_2 - 1.2e-05 25.3 0.0 1.3e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Dynamin family Roc PF08477.11 MSTRG.91808.1_2 - 0.0014 18.7 0.0 0.0015 18.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.21 MSTRG.91808.1_2 - 0.0018 18.3 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 MSTRG.91808.1_2 - 0.0075 16.1 0.0 0.0075 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.16 MSTRG.91808.1_2 - 0.014 14.5 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Septin Ras PF00071.20 MSTRG.91808.1_2 - 0.037 13.5 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Ras family FeoB_N PF02421.16 MSTRG.91808.1_2 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B MCM PF00493.21 MSTRG.91808.1_2 - 0.19 10.6 0.0 0.2 10.6 0.0 1.0 1 0 0 1 1 1 0 MCM2/3/5 family COPR5 PF15340.4 MSTRG.64042.1_2 - 0.05 14.1 0.0 0.097 13.2 0.0 1.4 1 1 0 1 1 1 0 Cooperator of PRMT5 family PLU-1 PF08429.9 MSTRG.33215.1_3 - 0.0077 15.3 3.0 0.011 14.8 3.0 1.1 1 0 0 1 1 1 1 PLU-1-like protein ACR_tran PF00873.17 MSTRG.33215.1_3 - 0.02 12.4 2.4 0.024 12.2 2.4 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FAM76 PF16046.3 MSTRG.33215.1_3 - 0.2 10.8 4.1 0.27 10.4 4.1 1.1 1 0 0 1 1 1 0 FAM76 protein Cadherin_3 PF16184.3 MSTRG.65837.1_2 - 4.1e-35 120.0 0.0 5.8e-27 93.8 0.0 2.0 2 0 0 2 2 2 2 Cadherin-like XkdW PF09636.8 MSTRG.65837.1_2 - 0.079 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 XkdW protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.89363.1_1 - 2.2e-05 24.5 0.2 4e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.89363.1_2 - 0.0084 16.2 0.6 0.043 13.9 0.0 2.3 2 0 0 2 2 2 1 Transposase Pkinase PF00069.23 MSTRG.55915.1_1 - 2.9e-13 49.7 3.4 4.4e-13 49.1 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.55915.1_1 - 9.3e-07 28.2 0.0 3.3e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Vir_act_alpha_C PF10400.7 MSTRG.55915.1_1 - 0.38 11.3 13.1 0.24 12.0 1.4 3.3 3 1 0 3 3 3 0 Virulence activator alpha C-term Arb1 PF09692.8 MSTRG.125687.1_2 - 0.021 13.9 0.0 0.025 13.6 0.0 1.0 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 WHIM1 PF15612.4 MSTRG.62280.1_2 - 0.0039 16.6 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Uds1 PF15456.4 MSTRG.62280.1_2 - 0.12 12.4 4.2 0.23 11.5 4.2 1.5 1 1 0 1 1 1 0 Up-regulated During Septation Coiled-coil_56 PF09813.7 MSTRG.24247.1_1 - 3.9e-32 110.1 0.0 5.3e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Pox_I1 PF03289.11 MSTRG.24247.1_1 - 0.13 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus protein I1 NTP_transf_2 PF01909.21 MSTRG.103135.1_3 - 0.00043 20.4 0.0 0.00074 19.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.17 MSTRG.103135.1_3 - 0.14 12.2 0.9 0.25 11.5 0.9 1.4 1 0 0 1 1 1 0 Cid1 family poly A polymerase CAP_N PF01213.17 MSTRG.64472.1_3 - 4.1 6.7 6.2 5.4 6.3 6.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HTH_28 PF13518.4 MSTRG.85515.1_3 - 4.5e-07 29.8 0.6 5.7e-07 29.4 0.6 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.85515.1_3 - 6.1e-06 25.7 0.3 7e-06 25.5 0.3 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.13 MSTRG.85515.1_3 - 1.4e-05 24.9 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.4 MSTRG.85515.1_3 - 3.2e-05 23.5 0.0 4.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.4 MSTRG.85515.1_3 - 0.00017 20.8 2.3 0.00027 20.2 2.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.4 MSTRG.85515.1_3 - 0.00036 20.4 0.3 0.00036 20.4 0.3 1.3 2 0 0 2 2 2 1 Winged helix-turn helix CENP-B_N PF04218.11 MSTRG.85515.1_3 - 0.00055 19.4 0.0 0.00067 19.1 0.0 1.1 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain PAX PF00292.16 MSTRG.85515.1_3 - 0.003 17.3 0.1 0.0035 17.1 0.1 1.1 1 0 0 1 1 1 1 'Paired box' domain Sigma70_ECF PF07638.9 MSTRG.85515.1_3 - 0.038 13.7 0.1 0.046 13.5 0.1 1.1 1 0 0 1 1 1 0 ECF sigma factor HTH_Tnp_1 PF01527.18 MSTRG.85515.1_3 - 0.071 13.3 0.6 0.083 13.1 0.6 1.2 1 0 0 1 1 1 0 Transposase Trp_repressor PF01371.17 MSTRG.85515.1_3 - 0.083 12.9 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 Trp repressor protein HTH_24 PF13412.4 MSTRG.85515.1_3 - 0.085 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TetR_N PF00440.21 MSTRG.85515.1_3 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Bromodomain PF00439.23 MSTRG.51724.1_2 - 9.8e-111 361.9 11.4 8.8e-21 73.7 0.8 6.3 6 0 0 6 6 6 6 Bromodomain DUF1640 PF07798.9 MSTRG.51724.1_2 - 0.055 13.4 0.1 0.055 13.4 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Med15_fungi PF05397.10 MSTRG.51724.1_2 - 0.47 10.7 5.5 2.1 8.5 0.2 2.7 2 0 0 2 2 2 0 Mediator complex subunit 15 DUF948 PF06103.9 MSTRG.112339.1_1 - 5.1 7.3 9.3 80 3.5 9.3 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4334 PF14232.4 MSTRG.112339.1_3 - 0.029 14.2 2.3 33 4.4 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4334) Helicase_IV_N PF12462.6 MSTRG.67454.1_2 - 0.069 12.9 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Peptidase_M23 PF01551.20 MSTRG.11897.2_3 - 1.2e-05 25.2 0.3 3.1e-05 24.0 0.3 1.7 1 1 0 1 1 1 1 Peptidase family M23 DUF1231 PF06802.9 MSTRG.11897.2_3 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1231) Choline_kinase PF01633.18 MSTRG.122066.1_3 - 0.069 12.6 0.1 0.069 12.6 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF3509 PF12021.6 MSTRG.122066.1_3 - 0.14 11.8 5.1 0.15 11.7 1.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3509) IL31 PF15209.4 MSTRG.122066.1_3 - 0.57 9.8 4.0 0.33 10.6 1.2 1.9 2 1 0 2 2 2 0 Interleukin 31 DUF3373 PF11853.6 MSTRG.122066.1_3 - 1.7 7.2 4.4 2.5 6.6 4.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) ALMT PF11744.6 MSTRG.122066.1_3 - 3.6 6.2 11.9 4.5 5.9 11.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S46 PF10459.7 MSTRG.122066.1_3 - 4.8 5.6 11.8 5.9 5.3 11.8 1.0 1 0 0 1 1 1 0 Peptidase S46 Syntaxin-5_N PF11416.6 MSTRG.86464.1_1 - 1.8e-10 39.6 3.5 1.8e-10 39.6 3.5 2.3 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Cep3 PF16846.3 MSTRG.86464.1_1 - 0.015 13.7 0.9 0.018 13.4 0.9 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Apolipoprotein PF01442.16 MSTRG.86464.1_1 - 0.024 14.4 1.1 0.043 13.6 0.9 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TRPM_tetra PF16519.3 MSTRG.86464.1_1 - 0.096 12.7 0.4 0.35 10.9 0.4 1.9 1 0 0 1 1 1 0 Tetramerisation domain of TRPM NPV_P10 PF05531.10 MSTRG.86464.1_1 - 0.24 11.7 2.5 2.3 8.6 1.6 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-18_N PF10496.7 MSTRG.86464.1_1 - 0.59 10.3 4.2 0.43 10.7 0.2 2.5 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus MdcG PF10620.7 MSTRG.86464.1_3 - 0.071 12.7 0.1 0.099 12.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG C_tripleX PF02363.17 MSTRG.38564.1_1 - 8.1 6.8 7.5 91 3.6 7.5 2.2 1 1 0 1 1 1 0 Cysteine rich repeat A2M_N_2 PF07703.12 MSTRG.90202.1_1 - 1.3e-15 57.9 0.0 1.7e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin family N-terminal region ArsC PF03960.13 MSTRG.31846.1_3 - 0.39 10.6 5.8 45 4.0 0.2 3.8 4 0 0 4 4 4 0 ArsC family EAR PF07897.9 MSTRG.31846.1_3 - 8.4 6.0 13.0 37 3.9 0.1 3.9 3 1 1 4 4 4 0 Ethylene-responsive binding factor-associated repression Aldo_ket_red PF00248.19 MSTRG.141976.1_1 - 1e-28 100.2 0.0 1.3e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cys_knot PF00007.20 MSTRG.89711.1_1 - 1.7e-11 44.2 19.4 1.7e-11 44.2 19.4 3.4 1 1 0 2 2 2 1 Cystine-knot domain VWC PF00093.16 MSTRG.89711.1_1 - 3.8e-05 23.8 15.1 3.8e-05 23.8 15.1 3.9 3 1 0 3 3 3 2 von Willebrand factor type C domain ADAM_spacer1 PF05986.12 MSTRG.15455.1_1 - 7.7e-19 67.7 0.2 8.3e-19 67.6 0.2 1.0 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Chorein_N PF12624.5 MSTRG.8119.1_1 - 2.9e-17 62.7 0.0 3.9e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 RPEL PF02755.13 MSTRG.125042.1_3 - 4.1e-10 38.9 2.5 1.9e-09 36.8 0.7 2.2 2 0 0 2 2 2 1 RPEL repeat 6PF2K PF01591.16 MSTRG.127218.1_2 - 2e-101 337.8 0.2 2.7e-101 337.4 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.20 MSTRG.127218.1_2 - 1.5e-16 60.6 0.0 2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.4 MSTRG.127218.1_2 - 1.2e-05 25.4 0.0 2.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.4 MSTRG.127218.1_2 - 0.0066 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.8 MSTRG.127218.1_2 - 0.029 13.7 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.10 MSTRG.127218.1_2 - 0.12 11.6 0.0 0.26 10.4 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin TTL PF03133.13 MSTRG.99077.1_1 - 3.1e-37 128.2 2.1 3.7e-37 127.9 2.1 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Ski_Sno PF02437.15 MSTRG.48700.1_3 - 0.0057 16.3 0.2 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 SKI/SNO/DAC family DUF866 PF05907.11 MSTRG.140276.2_1 - 2.1e-24 86.0 0.0 2.6e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF866 PF05907.11 MSTRG.140276.2_3 - 9.1e-12 45.0 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Arrestin_C PF02752.20 MSTRG.98084.1_2 - 7.5e-06 26.2 0.0 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Sigma70_r4_2 PF08281.10 MSTRG.129702.1_1 - 0.007 15.9 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 C1_2 PF03107.14 MSTRG.129702.1_3 - 0.062 13.5 0.8 0.085 13.1 0.8 1.5 1 1 0 1 1 1 0 C1 domain DUF3915 PF13054.4 MSTRG.66804.1_3 - 1.4 8.8 4.5 2 8.3 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) LYRIC PF15686.3 MSTRG.82397.1_2 - 0.00025 20.6 0.0 0.00027 20.5 0.0 1.0 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family DUF1049 PF06305.9 MSTRG.82397.1_2 - 0.012 15.3 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Integrin_alpha PF00357.18 MSTRG.82397.1_2 - 0.014 15.2 0.2 0.026 14.4 0.2 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Collectrin PF16959.3 MSTRG.82397.1_2 - 0.043 13.4 1.5 0.052 13.1 1.5 1.2 1 0 0 1 1 1 0 Renal amino acid transporter DUF4083 PF13314.4 MSTRG.82397.1_2 - 0.06 13.2 0.2 0.079 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PsbJ PF01788.15 MSTRG.82397.1_2 - 0.071 12.9 5.9 0.12 12.2 5.9 1.3 1 0 0 1 1 1 0 PsbJ Adeno_E3_CR2 PF02439.13 MSTRG.82397.1_2 - 0.08 12.6 2.0 0.11 12.1 2.0 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4381 PF14316.4 MSTRG.82397.1_2 - 0.082 13.0 0.0 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.4 MSTRG.82397.1_2 - 0.087 13.5 0.0 0.11 13.2 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.10 MSTRG.82397.1_2 - 0.093 11.8 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4834 PF16118.3 MSTRG.82397.1_2 - 0.11 13.3 0.0 0.13 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3328 PF11807.6 MSTRG.82397.1_2 - 0.11 12.1 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3094 PF11293.6 MSTRG.82397.1_2 - 0.44 10.2 2.0 0.54 9.9 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Rad60-SLD PF11976.6 MSTRG.134495.1_1 - 1.6e-24 85.4 0.1 2.6e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.21 MSTRG.134495.1_1 - 3.2e-10 39.5 0.1 5.7e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family DDE_3 PF13358.4 MSTRG.77983.1_2 - 5.4e-12 45.5 0.1 7.2e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease UCH PF00443.27 MSTRG.107396.1_3 - 1.3e-08 34.5 0.0 1.3e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 MSTRG.107396.1_3 - 0.00012 21.7 0.0 0.00013 21.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cys_rich_KTR PF14205.4 MSTRG.107396.1_3 - 0.053 13.2 0.3 0.088 12.5 0.3 1.3 1 0 0 1 1 1 0 Cysteine-rich KTR WCCH PF03716.12 MSTRG.107396.1_3 - 0.057 12.9 4.3 0.11 12.1 4.3 1.4 1 0 0 1 1 1 0 WCCH motif zinc_ribbon_10 PF10058.7 MSTRG.107396.1_3 - 0.13 11.9 1.1 3.4 7.3 0.2 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Peptidase_C48 PF02902.17 MSTRG.97182.1_3 - 4e-08 33.2 0.0 4.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PH PF00169.27 MSTRG.74353.1_3 - 0.0042 17.4 0.0 0.0052 17.1 0.0 1.2 1 0 0 1 1 1 1 PH domain PC_rep PF01851.20 MSTRG.46519.1_1 - 1.7e-28 97.5 13.2 3.2e-07 30.3 0.8 4.4 4 0 0 4 4 4 4 Proteasome/cyclosome repeat HEAT_2 PF13646.4 MSTRG.46519.1_1 - 0.012 15.9 0.1 0.098 12.9 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats SPATA3 PF15662.3 MSTRG.128935.2_3 - 9.2 6.7 6.3 2.7 8.5 3.7 1.4 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family TatD_DNase PF01026.19 MSTRG.134156.1_2 - 7.2e-42 143.4 0.0 7.9e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Peptidase_C2 PF00648.19 MSTRG.49250.1_3 - 9.5e-51 172.4 0.0 1.2e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Cnn_1N PF07989.9 MSTRG.44789.1_3 - 0.039 13.9 0.5 0.053 13.5 0.5 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Y_phosphatase PF00102.25 MSTRG.83275.1_2 - 4.8e-57 193.1 0.1 5.7e-57 192.8 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FAA_hydrolase PF01557.16 MSTRG.23526.1_3 - 4.9e-26 91.6 0.0 6.1e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RabGGT_insert PF07711.9 MSTRG.3141.1_2 - 0.006 16.9 3.0 14 6.1 0.2 3.2 1 1 3 4 4 4 4 Rab geranylgeranyl transferase alpha-subunit, insert domain WD40 PF00400.30 MSTRG.137429.1_3 - 2.6e-12 46.9 2.7 9.4e-07 29.3 0.2 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.137429.1_3 - 7.1e-06 26.1 0.1 3.3e-05 24.0 0.1 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.10 MSTRG.137429.1_3 - 0.0098 13.8 0.1 0.039 11.8 0.1 1.7 1 1 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.3 MSTRG.137429.1_3 - 0.014 14.2 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.9 MSTRG.137429.1_3 - 0.042 13.6 0.0 0.066 12.9 0.0 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A IP_trans PF02121.16 MSTRG.105559.1_2 - 2.9e-45 154.7 0.1 3.3e-45 154.5 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Septin PF00735.16 MSTRG.72125.3_3 - 3.6e-97 324.8 2.3 3.6e-97 324.8 2.3 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.21 MSTRG.72125.3_3 - 1e-05 25.4 1.2 1.5e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.11 MSTRG.72125.3_3 - 0.00062 19.9 0.1 0.0018 18.3 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.4 MSTRG.72125.3_3 - 0.0017 18.5 1.0 0.0035 17.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain Atg14 PF10186.7 MSTRG.72125.3_3 - 0.002 17.1 8.2 0.0041 16.1 8.2 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fzo_mitofusin PF04799.11 MSTRG.72125.3_3 - 0.0036 16.7 4.7 0.0036 16.7 4.7 2.0 2 0 0 2 2 2 1 fzo-like conserved region AAA_16 PF13191.4 MSTRG.72125.3_3 - 0.0039 17.4 0.2 0.026 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.25 MSTRG.72125.3_3 - 0.0074 15.7 4.4 0.91 8.9 0.0 3.2 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.4 MSTRG.72125.3_3 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2959 PF11172.6 MSTRG.72125.3_3 - 0.024 14.5 7.1 0.043 13.7 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF1890 PF09001.9 MSTRG.72125.3_3 - 0.075 13.3 0.3 0.19 12.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) IMD PF08397.9 MSTRG.72125.3_3 - 0.17 11.1 16.5 0.4 9.9 16.5 1.5 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF258 PF03193.14 MSTRG.72125.3_3 - 0.17 11.6 5.6 0.59 9.9 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function, DUF258 Exonuc_VII_L PF02601.13 MSTRG.72125.3_3 - 0.27 10.6 8.4 0.45 9.9 8.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.12 MSTRG.72125.3_3 - 0.36 10.5 12.3 0.67 9.6 12.3 1.4 1 0 0 1 1 1 0 IncA protein DUF87 PF01935.15 MSTRG.72125.3_3 - 0.76 9.6 7.4 2.7 7.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.4 MSTRG.72125.3_3 - 3.1 8.1 26.6 2.8e+03 -1.5 26.5 2.4 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.4 MSTRG.72125.3_3 - 4.8 6.7 9.9 8.8 5.8 9.9 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.25 MSTRG.72125.3_3 - 5.1 7.5 8.1 0.21 12.0 0.2 2.4 2 2 0 2 2 2 0 ABC transporter DUF4407 PF14362.4 MSTRG.72125.3_3 - 6.3 5.9 8.1 9 5.4 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dynamin_N PF00350.21 MSTRG.72125.3_3 - 6.8 6.6 7.7 11 5.9 0.2 2.4 2 1 0 2 2 2 0 Dynamin family Sigma70_r4_2 PF08281.10 MSTRG.135620.1_3 - 0.014 14.9 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.4 MSTRG.135620.1_3 - 0.057 13.1 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.4 MSTRG.135620.1_3 - 0.075 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Phi-29_GP16_7 PF06720.9 MSTRG.58012.1_2 - 0.023 14.4 0.9 0.031 14.0 0.9 1.3 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 DivIC PF04977.13 MSTRG.58012.1_2 - 0.7 9.6 5.0 0.27 10.9 2.8 1.5 2 0 0 2 2 2 0 Septum formation initiator HAUS2 PF15003.4 MSTRG.23060.1_3 - 1.3e-05 24.9 0.0 1.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Baculo_PEP_C PF04513.10 MSTRG.23060.1_3 - 2.3e-05 24.4 0.4 2.7e-05 24.1 0.4 1.2 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Dor1 PF04124.10 MSTRG.23060.1_3 - 0.023 13.3 0.2 0.027 13.0 0.2 1.0 1 0 0 1 1 1 0 Dor1-like family DUF4795 PF16043.3 MSTRG.23060.1_3 - 0.068 12.6 0.1 0.074 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DDE_3 PF13358.4 MSTRG.51244.1_1 - 1.6e-06 27.8 0.2 2.4e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Cullin_Nedd8 PF10557.7 MSTRG.136586.1_3 - 1.5e-28 98.4 3.0 1.5e-28 98.4 3.0 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain Cullin PF00888.20 MSTRG.136586.1_3 - 2.5e-11 42.8 1.5 2.5e-11 42.8 1.5 2.0 2 0 0 2 2 2 2 Cullin family Rrf2 PF02082.18 MSTRG.136586.1_3 - 0.16 12.2 1.2 0.89 9.8 0.4 2.3 2 1 0 2 2 2 0 Transcriptional regulator RVT_1 PF00078.25 MSTRG.83662.1_2 - 0.039 13.3 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TGF_beta_GS PF08515.10 MSTRG.99796.1_1 - 4.8e-17 61.0 0.2 8.4e-17 60.2 0.2 1.4 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Syndecan PF01034.18 MSTRG.99796.1_1 - 0.02 14.7 1.1 0.031 14.0 1.1 1.3 1 0 0 1 1 1 0 Syndecan domain bcl-2I13 PF12201.6 MSTRG.89661.1_1 - 0.057 13.2 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing DNA_topoisoIV PF00521.18 MSTRG.31120.1_1 - 3.3e-34 118.4 0.1 3.6e-34 118.3 0.1 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A F-box PF00646.31 MSTRG.71614.1_3 - 0.0038 16.9 0.1 0.0054 16.4 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 MSTRG.71614.1_3 - 0.0061 16.3 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 F-box-like IRF PF00605.15 MSTRG.78542.1_2 - 3.8e-42 142.7 0.2 4.8e-42 142.4 0.2 1.1 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Mit_KHE1 PF10173.7 MSTRG.136718.1_3 - 0.34 10.9 3.0 0.45 10.4 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related BAR_3 PF16746.3 MSTRG.53133.1_3 - 6.4e-24 84.8 4.1 7.2e-24 84.6 4.1 1.0 1 0 0 1 1 1 1 BAR domain of APPL family Podoplanin PF05808.9 MSTRG.60977.1_3 - 0.0024 17.9 5.1 0.0047 16.9 5.1 1.4 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.3 MSTRG.60977.1_3 - 0.34 11.4 2.3 0.68 10.4 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4690) Sulfotransfer_2 PF03567.12 MSTRG.116958.1_2 - 3.9e-39 134.9 0.1 4.5e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase family AAA_21 PF13304.4 MSTRG.17675.1_1 - 0.0041 16.8 0.0 0.0054 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.25 MSTRG.17675.1_1 - 0.0045 17.4 0.0 0.0064 16.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.14 MSTRG.17675.1_1 - 0.029 14.1 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ras PF00071.20 MSTRG.17675.1_1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Ras family IstB_IS21 PF01695.15 MSTRG.17675.1_1 - 0.21 11.2 0.1 0.31 10.7 0.1 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Mcp5_PH PF12814.5 MSTRG.17675.1_2 - 0.029 14.4 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Histone PF00125.22 MSTRG.51168.1_2 - 1.8e-10 41.2 0.0 2.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 E_Pc_C PF06752.10 MSTRG.79855.1_2 - 4.4e-16 59.6 3.7 6.2e-16 59.1 3.7 1.2 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus Pkinase PF00069.23 MSTRG.5274.1_3 - 4.6e-08 32.6 0.0 5e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.5274.1_3 - 0.0023 17.2 0.0 0.0025 17.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 MSTRG.5274.1_3 - 0.028 13.6 0.0 0.028 13.6 0.0 1.0 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.23 MSTRG.78141.1_3 - 6.8e-06 25.5 0.0 7.7e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain BRCA2 PF00634.16 MSTRG.68813.1_1 - 0.082 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 BRCA2 repeat DUF957 PF06117.9 MSTRG.110795.1_3 - 0.04 13.8 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) RVT_1 PF00078.25 MSTRG.31162.1_3 - 0.0076 15.7 0.0 0.0087 15.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) cwf21 PF08312.10 MSTRG.76959.1_1 - 0.04 13.9 1.1 0.057 13.5 0.1 1.8 2 0 0 2 2 2 0 cwf21 domain Pro-kuma_activ PF09286.9 MSTRG.76959.1_1 - 0.065 13.4 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Pro-kumamolisin, activation domain PNTB PF02233.14 MSTRG.123819.1_2 - 7.4e-53 179.9 11.2 8.1e-53 179.8 11.2 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit 12TM_1 PF09847.7 MSTRG.123819.1_2 - 0.11 11.4 1.5 0.14 11.1 1.5 1.0 1 0 0 1 1 1 0 Membrane protein of 12 TMs Phage_holin_2_4 PF16082.3 MSTRG.123819.1_2 - 0.3 10.8 5.4 3.5 7.4 0.3 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DisA_N PF02457.14 MSTRG.142264.1_1 - 0.097 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding CCCAP PF15964.3 MSTRG.57704.1_3 - 1.4e-39 135.9 4.9 1.9e-39 135.4 4.9 1.2 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family DUF2959 PF11172.6 MSTRG.57704.1_3 - 0.0006 19.8 0.8 0.001 19.0 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Val_tRNA-synt_C PF10458.7 MSTRG.57704.1_3 - 0.022 14.9 1.7 0.21 11.8 0.2 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF2205 PF10224.7 MSTRG.57704.1_3 - 0.7 9.8 5.0 11 5.9 0.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Calpain_III PF01067.20 MSTRG.128307.1_2 - 0.016 15.3 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Calpain large subunit, domain III DUF5034 PF16437.3 MSTRG.128307.1_2 - 0.1 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5034) AFG1_ATPase PF03969.14 MSTRG.66856.1_2 - 0.0036 16.1 0.1 0.0043 15.8 0.1 1.0 1 0 0 1 1 1 1 AFG1-like ATPase RVT_1 PF00078.25 MSTRG.134677.1_2 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hirudin PF00713.15 MSTRG.71425.1_2 - 0.022 14.9 1.4 0.022 14.9 1.4 2.0 1 1 1 2 2 2 0 Hirudin 2-oxoacid_dh PF00198.21 MSTRG.71425.1_3 - 1.4e-19 70.3 0.1 1.5e-19 70.2 0.1 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DUF4234 PF14018.4 MSTRG.138178.1_1 - 0.019 14.9 0.6 0.051 13.6 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) OCIA PF07051.9 MSTRG.14261.1_3 - 2.6e-14 52.9 0.0 4.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) Pkinase_Tyr PF07714.15 MSTRG.53155.1_3 - 6.6e-96 320.4 0.0 9e-96 320.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 MSTRG.53155.1_3 - 8.1e-48 162.9 0.0 1.1e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.22 MSTRG.53155.1_3 - 9.2e-25 86.4 0.1 2e-24 85.3 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.26 MSTRG.53155.1_3 - 1.1e-16 60.0 0.2 2e-16 59.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 MSTRG.53155.1_3 - 7e-10 38.3 0.0 1.3e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 MSTRG.53155.1_3 - 4.2e-09 36.0 0.1 9.8e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain HECT PF00632.23 MSTRG.90695.1_3 - 1.8e-96 323.1 0.2 2.2e-96 322.8 0.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RecR PF02132.13 MSTRG.101933.1_2 - 0.047 13.1 0.2 0.085 12.3 0.2 1.3 1 0 0 1 1 1 0 RecR protein PRKCSH PF07915.11 MSTRG.8692.1_2 - 4e-15 56.4 4.0 4.7e-15 56.2 4.0 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF3310 PF11753.6 MSTRG.142956.1_2 - 0.14 12.2 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) ERM PF00769.17 MSTRG.142956.1_3 - 1.8e-62 211.2 41.1 2.1e-62 211.0 41.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Pkinase PF00069.23 MSTRG.76721.1_3 - 1.9e-13 50.3 0.1 3.1e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.76721.1_3 - 1.2e-08 34.5 0.3 1.6e-08 34.0 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_29 PF13551.4 MSTRG.74106.1_2 - 1.6e-06 27.9 1.7 2.1e-06 27.5 1.7 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.4 MSTRG.74106.1_2 - 0.00017 21.5 1.4 0.00021 21.2 1.4 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.74106.1_2 - 0.0005 19.7 0.2 0.0007 19.2 0.2 1.3 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.16 MSTRG.74106.1_2 - 0.00059 19.6 0.2 0.00072 19.3 0.2 1.0 1 0 0 1 1 1 1 'Paired box' domain HTH_31 PF13560.4 MSTRG.74106.1_2 - 0.001 19.3 3.7 0.0013 18.9 3.7 1.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.4 MSTRG.74106.1_2 - 0.0043 17.5 4.2 0.0054 17.2 2.7 1.8 1 1 1 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.10 MSTRG.74106.1_2 - 0.031 13.8 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.4 MSTRG.74106.1_2 - 0.045 13.4 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.3 MSTRG.74106.1_2 - 0.049 12.5 0.0 0.052 12.4 0.0 1.0 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_26 PF13443.4 MSTRG.74106.1_2 - 0.15 12.4 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain GerE PF00196.17 MSTRG.74106.1_2 - 0.16 11.4 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family CH PF00307.29 MSTRG.93376.1_2 - 3.3e-17 62.5 0.0 4.6e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.16 MSTRG.93376.1_2 - 1.1e-11 44.0 5.4 1.1e-11 44.0 5.4 2.4 2 1 0 2 2 2 1 Calponin family repeat DDE_3 PF13358.4 MSTRG.119722.1_2 - 5.5e-06 26.1 0.0 5.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Vps53_N PF04100.10 MSTRG.54309.1_1 - 2.7e-29 102.2 0.0 2.9e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Vps53-like, N-terminal Baculo_11_kDa PF06143.9 MSTRG.76285.1_3 - 0.015 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family UL45 PF05473.10 MSTRG.76285.1_3 - 0.11 12.0 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF4834 PF16118.3 MSTRG.76285.1_3 - 0.11 13.3 0.0 0.15 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2500 PF10694.7 MSTRG.76285.1_3 - 0.18 12.3 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) PetG PF02529.13 MSTRG.76285.1_3 - 2.6 7.9 6.5 9 6.1 6.3 1.9 1 1 1 2 2 2 0 Cytochrome B6-F complex subunit 5 zf-C3H2C3 PF17122.3 MSTRG.119787.1_1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger HTH_psq PF05225.14 MSTRG.119787.1_1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DDE_3 PF13358.4 MSTRG.119787.1_2 - 2.9e-07 30.2 0.7 3.8e-07 29.8 0.7 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TIMP PF00965.15 MSTRG.36856.1_2 - 2.5e-71 239.1 5.9 3.5e-71 238.7 5.9 1.2 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.19 MSTRG.36856.1_2 - 0.02 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Glutaminase PF04960.13 MSTRG.91842.2_2 - 1.8e-22 79.8 0.1 2.4e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 Glutaminase Glutaminase PF04960.13 MSTRG.91842.2_3 - 1.9e-39 135.4 0.0 2.8e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Glutaminase TSC22 PF01166.16 MSTRG.142160.1_2 - 1.4e-20 73.2 3.1 2e-20 72.7 3.1 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family DivIC PF04977.13 MSTRG.142160.1_2 - 0.018 14.7 0.7 0.025 14.2 0.7 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.11 MSTRG.142160.1_2 - 0.025 15.1 1.6 0.029 14.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GDP_Man_Dehyd PF16363.3 MSTRG.70746.1_2 - 9.3e-09 35.0 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.19 MSTRG.70746.1_2 - 3.5e-05 23.3 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family STAR_dimer PF16544.3 MSTRG.64279.1_2 - 4.4e-24 83.7 0.1 9.9e-24 82.5 0.1 1.6 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein Quaking_NLS PF16551.3 MSTRG.64279.1_2 - 1.5e-14 53.2 2.9 2.7e-14 52.4 2.9 1.4 1 0 0 1 1 1 1 Putative nuclear localisation signal of quaking KH_1 PF00013.27 MSTRG.64279.1_2 - 3.3e-06 26.7 0.0 6.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 KH domain DUF2294 PF10057.7 MSTRG.64279.1_2 - 0.081 13.0 0.7 0.4 10.7 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2294) RVT_1 PF00078.25 MSTRG.67680.1_3 - 9.9e-07 28.4 0.1 1.4e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) I-set PF07679.14 MSTRG.2892.1_3 - 4e-08 33.1 0.0 5.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.2892.1_3 - 1.1e-05 25.8 0.0 1.6e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.2892.1_3 - 7.4e-05 22.7 0.0 0.00028 20.9 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 MSTRG.2892.1_3 - 0.00072 19.6 0.0 0.001 19.1 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.4 MSTRG.2892.1_3 - 0.02 15.1 0.0 0.036 14.3 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin domain RVT_1 PF00078.25 MSTRG.92827.1_1 - 1.9e-07 30.7 0.0 2e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_30kDa PF00329.17 MSTRG.130.1_2 - 1.2e-43 148.5 0.1 1.6e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Lsm_interact PF05391.9 MSTRG.130.1_2 - 0.15 11.5 0.1 0.35 10.3 0.1 1.6 1 0 0 1 1 1 0 Lsm interaction motif RhoGEF PF00621.18 MSTRG.127031.1_2 - 5e-21 75.6 0.6 6.4e-21 75.3 0.6 1.2 1 0 0 1 1 1 1 RhoGEF domain Myosin_head PF00063.19 MSTRG.43694.1_1 - 3.2e-07 28.8 0.0 4.6e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_head PF00063.19 MSTRG.43694.1_2 - 1.2e-14 53.4 0.0 1.5e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Gloverin PF10793.7 MSTRG.115475.1_3 - 0.043 13.5 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 Gloverin-like protein C2 PF00168.28 MSTRG.115475.1_3 - 0.083 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 C2 domain Troponin PF00992.18 MSTRG.112671.1_3 - 9.3e-47 158.6 8.4 9.3e-47 158.6 8.4 1.4 2 0 0 2 2 2 1 Troponin Integrin_B_tail PF07965.10 MSTRG.58069.1_1 - 3.7e-14 52.9 3.3 3.7e-14 52.9 3.3 4.7 2 1 2 4 4 4 1 Integrin beta tail domain Integrin_b_cyt PF08725.9 MSTRG.58069.1_1 - 6.6e-06 25.6 0.9 1e-05 25.0 0.9 1.3 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.11 MSTRG.58069.1_1 - 3.7e-05 23.8 63.7 0.00056 20.1 15.7 7.6 5 2 1 7 7 7 4 EGF-like domain HTH_38 PF13936.4 MSTRG.76079.1_1 - 5.1e-06 26.0 0.0 8.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.76079.1_1 - 0.0012 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.4 MSTRG.76079.1_1 - 0.0039 16.4 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.13 MSTRG.76079.1_1 - 0.0088 16.0 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Ribosomal_S13_N PF08069.10 MSTRG.76079.1_1 - 0.034 14.1 2.2 0.098 12.6 0.2 2.5 2 1 1 3 3 3 0 Ribosomal S13/S15 N-terminal domain DDE_3 PF13358.4 MSTRG.87890.1_1 - 3.3e-06 26.8 0.0 1.1e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease MOR2-PAG1_N PF14222.4 MSTRG.142537.3_2 - 0.021 13.7 0.2 0.044 12.6 0.0 1.5 2 0 0 2 2 2 0 Cell morphogenesis N-terminal zf-RING_10 PF16685.3 MSTRG.142537.3_2 - 0.34 11.0 1.5 0.56 10.2 1.5 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 MOR2-PAG1_N PF14222.4 MSTRG.142537.3_3 - 7.1e-08 31.7 0.0 7.9e-08 31.6 0.0 1.0 1 0 0 1 1 1 1 Cell morphogenesis N-terminal NapE PF06796.9 MSTRG.103459.1_1 - 0.14 11.6 0.9 5.7 6.4 0.2 2.4 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE I-set PF07679.14 MSTRG.72181.1_1 - 2.5e-10 40.1 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.72181.1_1 - 3.4e-09 37.0 0.0 6.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.72181.1_1 - 4.2e-06 26.7 0.0 1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.72181.1_1 - 4.3e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 MSTRG.72181.1_1 - 0.00018 21.5 0.3 0.0019 18.2 0.3 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Pkinase_Tyr PF07714.15 MSTRG.72181.1_1 - 0.00018 20.8 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TMIE PF16038.3 MSTRG.31122.1_1 - 0.33 10.7 1.7 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 TMIE protein RRM_1 PF00076.20 MSTRG.83300.2_1 - 2e-11 43.4 0.0 3.5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.81776.1_3 - 1.4e-10 41.1 6.8 2.5e-10 40.3 4.5 2.4 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.4 MSTRG.81776.1_3 - 0.00048 19.7 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.81776.1_3 - 0.0043 17.5 0.1 0.007 16.8 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.17 MSTRG.81776.1_3 - 0.033 14.0 0.1 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF4817 PF16087.3 MSTRG.81776.1_3 - 0.041 13.6 0.2 6.5 6.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4817) HTH_29 PF13551.4 MSTRG.81776.1_3 - 0.042 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.4 MSTRG.81776.1_3 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain RVT_1 PF00078.25 MSTRG.87900.1_1 - 6.7e-16 58.3 0.0 7.3e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Actin PF00022.17 MSTRG.33592.1_2 - 0.008 14.7 0.0 0.0087 14.6 0.0 1.0 1 0 0 1 1 1 1 Actin YfhO PF09586.8 MSTRG.93147.1_1 - 0.27 9.2 1.3 0.29 9.2 1.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4736 PF15883.3 MSTRG.121876.1_1 - 2 8.0 4.6 2.2 7.8 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) GPI2 PF06432.9 MSTRG.121876.1_2 - 2.8 7.2 13.2 3.1 7.0 13.2 1.0 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Ribosomal_60s PF00428.17 MSTRG.107452.1_3 - 4.6e-06 27.0 0.0 6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein TFIID_30kDa PF03540.11 MSTRG.107452.1_3 - 0.043 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit TFIID-31kDa PF02291.13 MSTRG.107452.1_3 - 0.16 11.9 0.0 0.84 9.6 0.0 1.7 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF4792 PF16040.3 MSTRG.15358.1_2 - 2.9 7.7 6.5 81 3.1 0.1 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4792) Melittin PF01372.15 MSTRG.15358.1_3 - 0.21 11.5 2.1 22 5.1 0.0 3.8 3 1 1 4 4 4 0 Melittin CRAM_rpt PF07016.9 MSTRG.134945.4_1 - 1.2 8.9 4.9 0.56 9.9 1.9 1.9 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor G-gamma PF00631.20 MSTRG.48566.1_1 - 0.0043 16.9 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 GGL domain SbcCD_C PF13558.4 MSTRG.61736.1_3 - 0.047 13.8 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit LRR_8 PF13855.4 MSTRG.5026.1_3 - 7.9e-25 86.3 14.5 1.4e-12 47.1 6.8 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 MSTRG.5026.1_3 - 1.3e-14 53.9 12.7 2e-05 24.7 3.0 3.7 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRRNT PF01462.16 MSTRG.5026.1_3 - 2.5e-07 30.1 6.1 2.5e-06 26.8 2.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.4 MSTRG.5026.1_3 - 0.00018 20.9 3.4 0.019 14.3 2.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.31 MSTRG.5026.1_3 - 0.0004 20.3 8.5 1.7 9.3 0.2 5.5 4 1 1 5 5 5 1 Leucine Rich Repeat LRR_5 PF13306.4 MSTRG.5026.1_3 - 0.0076 16.1 0.0 0.031 14.1 0.0 1.9 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.4 MSTRG.5026.1_3 - 0.03 14.2 11.2 8.7 6.6 0.2 5.0 5 0 0 5 5 5 0 Leucine Rich repeat FNIP PF05725.10 MSTRG.5026.1_3 - 1.7 8.7 4.8 40 4.4 4.1 3.0 2 1 0 2 2 2 0 FNIP Repeat WW PF00397.24 MSTRG.129478.1_1 - 4.4e-19 68.0 2.5 2e-08 33.9 0.1 2.5 2 0 0 2 2 2 2 WW domain Mod_r PF07200.11 MSTRG.129478.1_1 - 0.078 12.9 14.5 0.026 14.5 10.0 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.9 MSTRG.129478.1_1 - 1.2 7.8 13.6 7.3 5.2 5.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.13 MSTRG.129478.1_1 - 3.7 6.9 6.9 5.3 6.4 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Presenilin PF01080.15 MSTRG.51046.1_2 - 0.84 8.2 3.2 0.91 8.1 3.2 1.0 1 0 0 1 1 1 0 Presenilin DUF3915 PF13054.4 MSTRG.51046.1_3 - 1.3 8.9 4.2 1.7 8.5 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FAM27 PF15832.3 MSTRG.51046.1_3 - 6.3 7.3 37.7 0.47 10.9 28.7 2.2 1 1 1 2 2 2 0 FAM27 D and E protein family DUF1087 PF06465.11 MSTRG.18002.1_3 - 3.2e-24 84.6 4.9 3.2e-24 84.6 4.9 2.1 2 1 0 2 2 2 1 Domain of Unknown Function (DUF1087) DUF1086 PF06461.9 MSTRG.18002.1_3 - 3e-08 33.5 1.8 2.9e-07 30.3 0.1 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) CDC45 PF02724.12 MSTRG.18002.1_3 - 3.9 5.5 8.3 4.4 5.4 8.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Collagen PF01391.16 MSTRG.76144.1_2 - 0.033 13.8 0.7 0.046 13.4 0.7 1.1 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) SSP160 PF06933.9 MSTRG.76144.1_2 - 0.033 12.3 1.4 0.036 12.1 1.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ig PF00047.23 MSTRG.7795.1_2 - 2.4e-07 30.7 0.8 0.0017 18.3 0.4 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 MSTRG.7795.1_2 - 1.2e-06 28.9 0.0 0.0087 16.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 MSTRG.7795.1_2 - 0.00024 21.0 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.15 MSTRG.7795.1_2 - 0.00054 20.0 0.4 0.91 9.6 0.1 2.9 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.4 MSTRG.7795.1_2 - 0.00086 19.5 0.4 0.058 13.6 0.2 2.5 2 1 0 2 2 2 1 Immunoglobulin domain Mu-like_Com PF10122.7 MSTRG.79123.1_2 - 0.11 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Mu-like prophage protein Com DUF1769 PF08588.8 MSTRG.42444.1_3 - 0.043 13.9 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) FANCI_S2 PF14676.4 MSTRG.72075.1_1 - 0.048 13.8 0.7 0.11 12.6 0.2 1.9 2 1 0 2 2 2 0 FANCI solenoid 2 Nipped-B_C PF12830.5 MSTRG.72075.1_1 - 0.083 12.7 1.1 0.18 11.6 1.1 1.8 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus Pkinase PF00069.23 MSTRG.44818.1_3 - 1e-12 47.9 0.0 1.1e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.44818.1_3 - 2.9e-07 29.9 0.0 3.1e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S5 PF00333.18 MSTRG.57772.1_1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Ricin_B_lectin PF00652.20 MSTRG.39991.1_2 - 1.7e-11 44.3 0.2 2.2e-11 44.0 0.2 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PLRV_ORF5 PF01690.15 MSTRG.84204.1_1 - 1.3 7.5 2.6 1.6 7.3 2.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein zf-C2HE PF16278.3 MSTRG.84204.1_2 - 0.0099 16.2 2.7 0.0099 16.2 2.7 1.7 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger SNAP-25 PF00835.17 MSTRG.60701.1_1 - 3e-19 68.9 3.3 5.6e-19 68.1 0.6 2.3 2 0 0 2 2 2 1 SNAP-25 family DUF5089 PF17002.3 MSTRG.60701.1_1 - 0.0022 17.7 0.5 0.0022 17.7 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.6 MSTRG.60701.1_1 - 0.17 12.1 8.5 0.16 12.2 3.7 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus MCPsignal PF00015.19 MSTRG.60701.1_1 - 1.3 8.6 6.5 6 6.4 0.4 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Alanine_zipper PF11839.6 MSTRG.60701.1_1 - 2.5 8.3 5.7 5 7.3 0.9 2.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein RmuC PF02646.14 MSTRG.60701.1_1 - 3.3 6.6 8.3 0.48 9.4 0.4 2.1 2 0 0 2 2 2 0 RmuC family DivIC PF04977.13 MSTRG.60701.1_1 - 9.5 5.9 6.7 15 5.3 1.6 2.3 2 0 0 2 2 2 0 Septum formation initiator MAD PF05557.11 MSTRG.60701.1_1 - 9.6 4.3 12.4 0.25 9.5 1.5 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein RNase_Zc3h12a PF11977.6 MSTRG.113623.1_3 - 8.8e-21 74.2 0.0 9.5e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Bim_N PF06773.9 MSTRG.142555.1_1 - 0.089 12.4 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Bim protein N-terminus FtsL PF04999.11 MSTRG.24533.1_1 - 0.0064 16.3 12.9 0.057 13.3 4.4 2.0 1 1 1 2 2 2 2 Cell division protein FtsL JIP_LZII PF16471.3 MSTRG.24533.1_1 - 0.044 13.8 14.9 0.08 13.0 14.9 1.4 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II CENP-F_leu_zip PF10473.7 MSTRG.24533.1_1 - 0.045 13.6 17.2 0.052 13.4 17.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2244 PF10003.7 MSTRG.24533.1_1 - 0.055 13.0 6.1 1.7 8.2 6.1 2.3 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) DUF3450 PF11932.6 MSTRG.24533.1_1 - 0.074 12.2 10.7 0.086 12.0 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3093 PF11292.6 MSTRG.24533.1_1 - 0.23 11.5 0.6 9.9 6.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3093) APG6 PF04111.10 MSTRG.24533.1_1 - 0.52 9.5 12.4 0.57 9.4 12.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF5101 PF17031.3 MSTRG.24533.1_1 - 0.68 9.9 10.6 7.2 6.6 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5101) DUF874 PF05917.9 MSTRG.24533.1_1 - 1.1 8.1 10.8 1.2 8.0 10.8 1.0 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Myc-LZ PF02344.13 MSTRG.24533.1_1 - 1.9 8.5 20.2 66 3.6 6.4 3.8 1 1 1 2 2 2 0 Myc leucine zipper domain DUF2681 PF10883.6 MSTRG.24533.1_1 - 1.9 8.8 15.5 2.6e+03 -1.2 15.5 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) FOXP-CC PF16159.3 MSTRG.24533.1_1 - 4.3 7.9 13.5 4.8 7.7 3.5 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF1669 PF07894.10 MSTRG.84801.1_1 - 6e-25 88.2 0.1 7.7e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) GCHY-1 PF02649.12 MSTRG.84801.1_3 - 0.28 10.5 1.0 0.33 10.3 1.0 1.0 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Annexin PF00191.18 MSTRG.80947.1_3 - 5.2e-43 144.8 2.9 1.5e-21 76.1 0.3 2.2 2 0 0 2 2 2 2 Annexin T4_tail_cap PF11091.6 MSTRG.80947.1_3 - 0.068 12.0 0.3 0.99 8.1 0.0 2.0 1 1 1 2 2 2 0 Tail-tube assembly protein Pkinase PF00069.23 MSTRG.93102.1_2 - 7.5e-06 25.4 0.0 9.2e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Mak16 PF04874.12 MSTRG.93102.1_2 - 0.14 12.6 0.0 0.19 12.2 0.0 1.1 1 0 0 1 1 1 0 Mak16 protein C-terminal region DUF5101 PF17031.3 MSTRG.12030.2_1 - 0.00015 21.7 0.6 0.0002 21.3 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5101) CENP-F_leu_zip PF10473.7 MSTRG.12030.2_1 - 0.00015 21.7 6.9 0.00017 21.5 6.9 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mnd1 PF03962.13 MSTRG.12030.2_1 - 0.00062 19.6 3.0 0.00068 19.4 3.0 1.1 1 0 0 1 1 1 1 Mnd1 family Tweety PF04906.11 MSTRG.12030.2_1 - 0.0054 15.3 1.3 0.0063 15.1 1.3 1.0 1 0 0 1 1 1 1 Tweety BAR PF03114.16 MSTRG.12030.2_1 - 0.0061 16.1 1.6 0.008 15.7 1.6 1.1 1 0 0 1 1 1 1 BAR domain APG6 PF04111.10 MSTRG.12030.2_1 - 0.014 14.7 7.4 0.016 14.4 7.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF812 PF05667.9 MSTRG.12030.2_1 - 0.018 13.8 4.6 0.02 13.7 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HemX PF04375.12 MSTRG.12030.2_1 - 0.02 14.1 6.1 0.023 13.9 6.1 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF948 PF06103.9 MSTRG.12030.2_1 - 0.04 14.0 1.7 0.084 13.0 1.7 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.4 MSTRG.12030.2_1 - 0.061 11.9 2.6 0.072 11.6 2.6 1.0 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.10 MSTRG.12030.2_1 - 0.07 12.4 0.2 0.08 12.2 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein COG2 PF06148.9 MSTRG.12030.2_1 - 0.071 13.1 3.0 0.088 12.8 3.0 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.6 MSTRG.12030.2_1 - 0.076 12.9 8.3 0.11 12.3 3.9 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding YojJ PF10372.7 MSTRG.12030.2_1 - 0.092 12.7 0.6 0.2 11.6 0.6 1.6 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Laminin_II PF06009.10 MSTRG.12030.2_1 - 0.11 12.4 1.8 0.14 12.1 1.8 1.1 1 0 0 1 1 1 0 Laminin Domain II HR1 PF02185.14 MSTRG.12030.2_1 - 0.13 12.3 5.9 0.19 11.7 5.9 1.2 1 0 0 1 1 1 0 Hr1 repeat YscO-like PF16789.3 MSTRG.12030.2_1 - 0.14 12.1 6.9 0.17 11.8 6.9 1.1 1 0 0 1 1 1 0 YscO-like protein DUF342 PF03961.11 MSTRG.12030.2_1 - 0.14 10.6 1.2 0.15 10.5 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.12 MSTRG.12030.2_1 - 0.18 11.5 6.4 0.22 11.1 6.4 1.1 1 0 0 1 1 1 0 IncA protein Sec34 PF04136.13 MSTRG.12030.2_1 - 0.18 11.5 3.0 0.27 11.0 0.6 1.5 1 1 0 1 1 1 0 Sec34-like family DUF4407 PF14362.4 MSTRG.12030.2_1 - 0.24 10.6 2.3 0.29 10.3 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cauli_AT PF03233.11 MSTRG.12030.2_1 - 0.27 11.0 1.5 0.33 10.7 1.5 1.1 1 0 0 1 1 1 0 Aphid transmission protein DUF972 PF06156.11 MSTRG.12030.2_1 - 0.28 11.7 4.5 0.41 11.2 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Cnn_1N PF07989.9 MSTRG.12030.2_1 - 0.31 11.0 7.4 2.1 8.4 7.5 2.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.10 MSTRG.12030.2_1 - 0.32 10.8 2.8 0.43 10.4 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2968 PF11180.6 MSTRG.12030.2_1 - 0.53 9.8 8.4 0.72 9.4 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) UPF0449 PF15136.4 MSTRG.12030.2_1 - 0.58 10.5 5.1 0.82 10.0 5.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 JIP_LZII PF16471.3 MSTRG.12030.2_1 - 0.64 10.1 9.5 0.39 10.8 1.7 2.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II V_ATPase_I PF01496.17 MSTRG.12030.2_1 - 0.77 7.4 3.6 0.85 7.3 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.7 MSTRG.12030.2_1 - 0.91 9.6 4.9 1.2 9.3 4.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein CCDC-167 PF15188.4 MSTRG.12030.2_1 - 2.9 8.2 7.4 4.1 7.7 7.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 bZIP_2 PF07716.13 MSTRG.12030.2_1 - 4.5 7.3 8.5 10 6.2 2.3 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.13 MSTRG.12030.2_1 - 7 6.4 8.3 13 5.5 0.8 2.1 1 1 1 2 2 2 0 Septum formation initiator HigB_toxin PF09907.7 MSTRG.89847.1_3 - 0.13 12.3 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DOR PF14839.4 MSTRG.91606.3_3 - 3.3e-30 105.7 4.5 3.3e-30 105.7 4.5 2.4 2 1 1 3 3 3 1 DOR family WD40 PF00400.30 MSTRG.4648.1_1 - 2e-05 25.1 5.9 0.0013 19.4 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat FISNA PF14484.4 MSTRG.1571.2_2 - 9.9e-36 121.7 8.7 6e-35 119.2 0.8 3.4 4 0 0 4 4 4 2 Fish-specific NACHT associated domain NACHT PF05729.10 MSTRG.1571.2_2 - 1.6e-31 109.4 0.1 6.7e-31 107.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain PYRIN PF02758.14 MSTRG.1571.2_2 - 7.2e-05 22.8 2.6 0.015 15.4 1.2 4.4 3 1 0 3 3 3 1 PAAD/DAPIN/Pyrin domain ADIP PF11559.6 MSTRG.144157.1_1 - 0.0012 18.8 5.5 0.0014 18.6 5.5 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF2390 PF09523.8 MSTRG.144157.1_1 - 0.036 14.3 1.6 0.036 14.3 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) Rho_Binding PF08912.9 MSTRG.144157.1_1 - 0.24 12.1 3.5 0.54 11.0 2.5 1.8 1 1 1 2 2 2 0 Rho Binding DUF2576 PF10845.6 MSTRG.144157.1_1 - 0.25 10.8 3.9 3.1 7.3 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2576) IncA PF04156.12 MSTRG.144157.1_1 - 2.5 7.7 8.0 3.5 7.2 6.2 1.6 1 1 0 1 1 1 0 IncA protein TACC PF05010.12 MSTRG.64950.1_3 - 3.6e-77 258.6 28.8 3.6e-77 258.6 28.8 1.8 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) MnmE_helical PF12631.5 MSTRG.64950.1_3 - 0.27 11.2 4.2 0.5 10.3 4.2 1.4 1 0 0 1 1 1 0 MnmE helical domain Choline_transpo PF04515.10 MSTRG.74864.1_2 - 3.6e-07 29.6 5.8 3.6e-07 29.6 5.8 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter TrbL PF04610.12 MSTRG.74864.1_2 - 0.15 11.7 18.8 0.14 11.8 9.9 2.1 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein DUF4131 PF13567.4 MSTRG.74864.1_2 - 1.6 8.2 14.5 0.11 12.0 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CobS PF02654.13 MSTRG.74864.1_2 - 2.4 8.2 13.7 0.6 10.1 7.0 2.0 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase DUF805 PF05656.12 MSTRG.74864.1_2 - 4.3 7.7 13.3 3.1 8.1 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) PDR_assoc PF08370.9 MSTRG.74864.1_2 - 5.6 6.6 10.2 0.34 10.5 2.7 2.4 2 1 0 2 2 2 0 Plant PDR ABC transporter associated SUZ-C PF12901.5 MSTRG.67993.1_1 - 0.037 14.0 0.3 0.083 12.8 0.3 1.6 1 0 0 1 1 1 0 SUZ-C motif Totivirus_coat PF05518.9 MSTRG.67993.1_2 - 6.9 4.5 9.8 8.1 4.2 9.8 1.0 1 0 0 1 1 1 0 Totivirus coat protein Inhibitor_I66 PF16850.3 MSTRG.50207.1_3 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I66 CFC PF09443.8 MSTRG.13997.1_2 - 0.027 14.2 0.2 0.071 12.9 0.2 1.8 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) DUF21 PF01595.18 MSTRG.42061.1_2 - 1.2e-11 44.5 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 RVT_1 PF00078.25 MSTRG.12265.1_2 - 1.9e-08 34.0 0.0 2.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SYF2 PF08231.10 MSTRG.3609.1_3 - 3.9e-55 186.5 10.1 3.9e-55 186.5 10.1 1.9 2 1 0 2 2 2 1 SYF2 splicing factor DHR-2 PF06920.11 MSTRG.109601.1_1 - 1.2e-143 479.5 3.2 1.3e-143 479.3 3.2 1.0 1 0 0 1 1 1 1 Dock homology region 2 Metal_resist PF13801.4 MSTRG.109601.1_1 - 0.12 12.4 0.1 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal resistance Ras PF00071.20 MSTRG.1301.1_2 - 2.3e-58 196.2 0.2 2.8e-58 196.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 MSTRG.1301.1_2 - 1.4e-32 112.3 0.1 2e-32 111.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 MSTRG.1301.1_2 - 3.7e-14 52.4 0.1 4.9e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 MSTRG.1301.1_2 - 4e-05 23.1 0.1 0.0014 18.0 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 MSTRG.1301.1_2 - 0.00016 21.6 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 MSTRG.1301.1_2 - 0.0014 17.9 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.8 MSTRG.1301.1_2 - 0.004 16.5 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.14 MSTRG.1301.1_2 - 0.0077 16.0 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ATPase_2 PF01637.16 MSTRG.1301.1_2 - 0.026 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.15 MSTRG.1301.1_2 - 0.028 14.0 0.0 4.8 6.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.4 MSTRG.1301.1_2 - 0.051 13.8 0.0 0.084 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.4 MSTRG.1301.1_2 - 0.071 13.2 0.1 0.33 11.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.7 MSTRG.1301.1_2 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.11 MSTRG.1301.1_2 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.10 MSTRG.1301.1_2 - 0.15 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF1242 PF06842.10 MSTRG.58553.1_1 - 0.17 11.6 0.6 0.17 11.6 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) DUF938 PF06080.10 MSTRG.52549.1_2 - 2.9e-05 23.8 0.0 3.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Rop PF01815.14 MSTRG.139389.1_1 - 0.14 11.9 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Rop protein Pkinase PF00069.23 MSTRG.65954.1_1 - 3.1e-23 82.4 0.1 3.1e-23 82.4 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.65954.1_1 - 1.8e-11 43.7 0.0 1.8e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.20 MSTRG.65954.1_1 - 0.038 13.4 1.5 0.086 12.3 0.1 2.1 2 0 0 2 2 2 0 RIO1 family HNOB PF07700.13 MSTRG.65954.1_1 - 0.048 13.5 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Haem-NO-binding Lysis_col PF02402.14 MSTRG.105571.1_3 - 0.014 15.1 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Lysis protein ABC_tran PF00005.25 MSTRG.133822.1_3 - 2.6e-23 82.9 0.8 1e-22 81.0 0.0 2.2 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.14 MSTRG.133822.1_3 - 0.0008 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.17 MSTRG.133822.1_3 - 0.001 18.4 0.1 0.31 10.3 0.1 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.4 MSTRG.133822.1_3 - 0.0015 18.8 0.1 0.0065 16.7 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.4 MSTRG.133822.1_3 - 0.0083 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.21 MSTRG.133822.1_3 - 0.02 14.8 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.21 MSTRG.133822.1_3 - 0.03 14.3 0.1 0.03 14.3 0.1 1.8 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.4 MSTRG.133822.1_3 - 0.13 12.4 0.8 0.61 10.2 0.0 2.3 2 1 1 3 3 3 0 AAA domain DUF815 PF05673.11 MSTRG.133822.1_3 - 0.14 11.1 0.2 0.34 9.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) zf-C2H2 PF00096.24 MSTRG.83590.2_1 - 4e-18 64.7 29.2 5e-06 26.5 2.2 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.83590.2_1 - 2.4e-16 59.2 29.1 1.9e-08 34.2 2.0 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.83590.2_1 - 8.3e-15 54.1 26.0 0.0017 18.9 1.9 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.83590.2_1 - 9.9e-09 35.2 11.2 0.33 11.2 0.1 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 MSTRG.83590.2_1 - 1.4e-07 31.1 19.8 0.00047 19.9 1.6 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-CHCC PF10276.7 MSTRG.83590.2_1 - 9.9e-05 22.2 1.9 0.14 12.1 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger domain zf-met PF12874.5 MSTRG.83590.2_1 - 0.0012 19.1 21.7 0.3 11.4 0.2 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type Prok-RING_1 PF14446.4 MSTRG.83590.2_1 - 0.0016 18.2 6.2 2.3 8.1 0.1 3.8 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 GAGA PF09237.9 MSTRG.83590.2_1 - 0.0026 17.4 2.7 1.2 8.9 0.2 2.5 1 1 1 2 2 2 2 GAGA factor HNH PF01844.21 MSTRG.83590.2_1 - 0.0063 16.5 14.3 0.53 10.4 0.7 4.2 4 0 0 4 4 4 1 HNH endonuclease zf-Di19 PF05605.10 MSTRG.83590.2_1 - 0.0087 16.2 13.4 0.041 14.0 5.1 2.8 2 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.13 MSTRG.83590.2_1 - 0.0092 15.9 21.1 0.063 13.2 2.5 4.1 2 1 2 4 4 4 2 BED zinc finger C1_1 PF00130.20 MSTRG.83590.2_1 - 0.02 14.6 9.6 0.3 10.9 2.8 3.0 2 2 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.3 MSTRG.83590.2_1 - 0.04 14.5 3.9 2.6 8.7 0.7 2.2 1 1 0 2 2 2 0 zinc-ribbon family XPA_N PF01286.16 MSTRG.83590.2_1 - 0.046 13.6 8.0 2.2 8.3 0.1 4.0 4 0 0 4 4 4 0 XPA protein N-terminal Zf_RING PF16744.3 MSTRG.83590.2_1 - 0.05 13.6 6.7 2.2 8.3 0.4 3.2 1 1 2 3 3 3 0 KIAA1045 RING finger Ta0938 PF11494.6 MSTRG.83590.2_1 - 0.063 13.4 0.6 0.27 11.4 0.2 2.1 1 1 1 2 2 2 0 Ta0938 HypA PF01155.17 MSTRG.83590.2_1 - 0.066 13.1 2.6 0.16 11.9 2.6 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HNH_5 PF14279.4 MSTRG.83590.2_1 - 0.073 12.8 9.9 1.2 8.9 0.9 3.9 4 0 0 4 4 4 0 HNH endonuclease PyrI_C PF02748.13 MSTRG.83590.2_1 - 0.084 12.7 5.5 0.36 10.6 0.2 3.0 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYVE PF01363.19 MSTRG.83590.2_1 - 0.14 12.2 16.5 0.11 12.5 4.1 3.3 2 1 2 4 4 4 0 FYVE zinc finger Zn-ribbon_8 PF09723.8 MSTRG.83590.2_1 - 0.35 10.9 10.3 1.5 8.9 4.7 3.4 2 1 2 4 4 4 0 Zinc ribbon domain YhfH PF14149.4 MSTRG.83590.2_1 - 0.74 9.7 6.0 7.8 6.4 0.5 2.9 2 1 1 3 3 3 0 YhfH-like protein zf-C2HC_2 PF13913.4 MSTRG.83590.2_1 - 0.91 9.4 14.7 0.43 10.4 1.0 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.5 MSTRG.83590.2_1 - 0.94 9.7 14.6 7.4 6.8 0.6 3.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) DZR PF12773.5 MSTRG.83590.2_1 - 1.5 8.7 8.7 4 7.4 8.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-LYAR PF08790.9 MSTRG.83590.2_1 - 2.4 8.0 14.3 1.6 8.6 1.3 4.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger UBZ_FAAP20 PF15750.3 MSTRG.83590.2_1 - 2.5 8.0 7.5 62 3.5 0.2 3.9 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger Ribosomal_L28 PF00830.17 MSTRG.83590.2_1 - 3.2 7.9 9.0 1.5 9.0 0.6 3.3 3 0 0 3 3 3 0 Ribosomal L28 family zf-AN1 PF01428.14 MSTRG.83590.2_1 - 6.4 6.9 15.4 1.4 9.0 0.8 3.6 3 1 1 4 4 3 0 AN1-like Zinc finger DDE_3 PF13358.4 MSTRG.48260.1_3 - 0.00053 19.6 0.1 0.0013 18.3 0.1 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HMG_CoA_synt_N PF01154.15 MSTRG.115228.1_3 - 0.012 15.4 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Ribosomal_S7e PF01251.16 MSTRG.123464.1_1 - 4.3e-11 42.8 0.0 5.5e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e KcnmB2_inactiv PF09303.8 MSTRG.105969.1_1 - 0.11 12.2 4.7 27 4.6 0.1 3.3 3 0 0 3 3 3 0 KCNMB2, ball and chain domain VKOR PF07884.12 MSTRG.137093.1_2 - 0.00049 20.1 0.1 0.00055 20.0 0.1 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family SANT_DAMP1_like PF16282.3 MSTRG.50032.2_1 - 1.5e-33 114.6 3.1 3.5e-33 113.5 3.1 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.10 MSTRG.50032.2_1 - 1.4e-30 106.3 7.8 1.4e-30 106.3 7.8 1.8 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.4 MSTRG.50032.2_1 - 0.048 13.8 2.7 0.17 12.0 0.1 2.9 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF2110 PF09883.7 MSTRG.50032.2_1 - 0.078 12.5 0.2 0.15 11.6 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) AP_endonuc_2 PF01261.22 MSTRG.50032.2_1 - 0.084 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel APG6 PF04111.10 MSTRG.50032.2_1 - 2.3 7.4 9.1 3.7 6.7 9.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Arrestin_N PF00339.27 MSTRG.134076.1_3 - 0.024 14.6 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain SH3_1 PF00018.26 MSTRG.141398.1_2 - 1.8e-22 78.5 3.8 5.4e-11 41.8 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 MSTRG.141398.1_2 - 5.5e-21 74.0 1.1 2.2e-11 43.3 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.15 MSTRG.141398.1_2 - 5.9e-21 73.8 0.1 1.1e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.9 MSTRG.141398.1_2 - 1.2e-06 28.6 4.3 0.0098 16.0 0.3 2.3 2 0 0 2 2 2 2 Bacterial SH3 domain hSH3 PF14603.4 MSTRG.141398.1_2 - 0.014 15.8 0.0 1.6 9.2 0.0 2.8 3 0 0 3 3 3 0 Helically-extended SH3 domain SH3_6 PF12913.5 MSTRG.141398.1_2 - 0.11 11.9 2.7 0.23 10.9 0.2 2.2 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) BMF PF15185.4 MSTRG.140720.1_1 - 7e-09 35.5 5.2 1.1e-08 34.9 5.2 1.5 1 1 0 1 1 1 1 Bcl-2-modifying factor, apoptosis SMP_LBD PF17047.3 MSTRG.142758.1_2 - 1.9e-27 95.8 2.3 3.8e-27 94.8 2.3 1.5 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.28 MSTRG.142758.1_2 - 8.2e-21 74.1 0.0 1.1e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 C2 domain zf-C2H2 PF00096.24 MSTRG.44347.1_1 - 5.3e-05 23.3 1.7 0.52 10.7 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.44347.1_1 - 0.00066 20.2 2.6 1.3 9.9 0.7 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zinc_ribbon_10 PF10058.7 MSTRG.44347.1_1 - 0.043 13.4 0.2 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF16 PF01519.14 MSTRG.101104.1_2 - 0.044 14.1 0.0 0.054 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Exo_endo_phos_2 PF14529.4 MSTRG.103812.1_3 - 0.077 12.7 0.0 0.092 12.5 0.0 1.1 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase TPR_9 PF13371.4 MSTRG.131958.1_1 - 2.5e-05 24.2 0.6 4.4e-05 23.4 0.6 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.15 MSTRG.131958.1_1 - 0.0022 17.8 1.2 0.063 13.3 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.4 MSTRG.131958.1_1 - 0.0033 17.8 2.2 0.004 17.5 0.3 2.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.4 MSTRG.131958.1_1 - 0.0033 17.4 0.1 0.014 15.5 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat T3SS_LEE_assoc PF13327.4 MSTRG.131958.1_1 - 0.017 15.0 0.2 0.027 14.4 0.2 1.3 1 0 0 1 1 1 0 Type III secretion system subunit TPR_1 PF00515.26 MSTRG.131958.1_1 - 0.035 13.8 2.1 4.1 7.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.4 MSTRG.131958.1_1 - 0.061 13.9 0.3 0.18 12.4 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.4 MSTRG.131958.1_1 - 0.085 13.2 0.1 31 5.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Collagen PF01391.16 MSTRG.104490.1_1 - 0.015 14.9 17.7 0.039 13.6 17.7 1.7 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_L1 PF00687.19 MSTRG.104490.1_2 - 3.4e-48 164.0 0.2 6.8e-48 163.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pro-rich PF15240.4 MSTRG.104490.1_2 - 0.024 14.9 16.4 0.036 14.3 16.4 1.2 1 0 0 1 1 1 0 Proline-rich TnsD PF15978.3 MSTRG.104490.1_2 - 0.12 11.1 2.0 0.44 9.3 0.1 2.1 1 1 1 2 2 2 0 Tn7-like transposition protein D Presenilin PF01080.15 MSTRG.104490.1_2 - 0.16 10.6 1.7 0.19 10.3 1.7 1.1 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.24 MSTRG.144285.1_3 - 1.8e-17 62.6 27.7 0.0007 19.8 0.2 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.144285.1_3 - 7.6e-17 60.4 27.0 0.0013 19.2 0.9 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.144285.1_3 - 4.2e-14 52.3 9.8 8.2e-06 25.9 0.1 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 MSTRG.144285.1_3 - 8.1e-14 51.4 12.8 1.8e-05 24.8 0.3 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 MSTRG.144285.1_3 - 9.6e-11 41.2 16.1 0.022 14.6 0.0 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.4 MSTRG.144285.1_3 - 1.3e-10 41.1 33.9 4.1e-06 26.9 0.5 6.2 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_2 PF12756.5 MSTRG.144285.1_3 - 0.00057 20.0 22.4 0.47 10.7 0.4 5.4 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) Cys_rich_CPXG PF14255.4 MSTRG.144285.1_3 - 0.00089 19.0 0.6 0.00089 19.0 0.6 3.6 4 0 0 4 4 4 1 Cysteine-rich CPXCG zf-Di19 PF05605.10 MSTRG.144285.1_3 - 0.01 16.0 19.4 2.9 8.1 5.8 4.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.17 MSTRG.144285.1_3 - 0.092 12.6 15.4 0.073 13.0 3.9 3.7 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.9 MSTRG.144285.1_3 - 0.1 12.4 13.0 0.43 10.4 0.4 3.6 2 1 1 3 3 3 0 Putative transposase DNA-binding domain HnRNPA1 PF11627.6 MSTRG.144285.1_3 - 0.13 12.2 0.0 9.5 6.3 0.1 3.3 3 0 0 3 3 3 0 Nuclear factor hnRNPA1 PyrI_C PF02748.13 MSTRG.144285.1_3 - 0.18 11.6 12.0 2.4 8.0 0.1 5.0 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.3 MSTRG.144285.1_3 - 1.4 8.6 18.5 11 5.8 3.3 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.8 MSTRG.144285.1_3 - 3.7 7.6 19.7 0.25 11.3 2.6 4.5 4 0 0 4 4 4 0 Zinc ribbon domain zf-3CxxC_2 PF17180.2 MSTRG.144285.1_3 - 4.4 8.0 19.9 1.3 9.7 0.3 4.1 2 1 2 4 4 4 0 Zinc-binding domain TF_Zn_Ribbon PF08271.10 MSTRG.144285.1_3 - 9.7 5.7 17.1 12 5.4 0.2 4.8 3 2 1 4 4 4 0 TFIIB zinc-binding ANF_receptor PF01094.26 MSTRG.54856.1_3 - 5.8e-05 22.2 0.0 6.4e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Thioredoxin PF00085.18 MSTRG.140625.1_2 - 4.1e-32 110.1 0.2 9.2e-32 109.0 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.11 MSTRG.140625.1_2 - 2e-05 24.0 0.2 0.00015 21.1 0.2 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 MSTRG.140625.1_2 - 0.0002 21.6 0.1 0.00085 19.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.4 MSTRG.140625.1_2 - 0.00074 19.4 0.1 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.4 MSTRG.140625.1_2 - 0.0027 17.9 0.1 0.014 15.6 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.4 MSTRG.140625.1_2 - 0.046 13.8 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like BRO1 PF03097.16 MSTRG.140625.1_2 - 0.046 12.4 0.0 0.047 12.4 0.0 1.0 1 0 0 1 1 1 0 BRO1-like domain AhpC-TSA PF00578.19 MSTRG.140625.1_2 - 0.065 13.0 0.1 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.4 MSTRG.140625.1_2 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin ANATO PF01821.16 MSTRG.16087.1_1 - 0.023 15.4 0.9 0.66 10.8 0.1 2.3 2 0 0 2 2 2 0 Anaphylotoxin-like domain Sigma70_r4_2 PF08281.10 MSTRG.16087.1_3 - 7.1e-06 25.5 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.4 MSTRG.16087.1_3 - 7.3e-06 25.5 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.4 MSTRG.16087.1_3 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.17 MSTRG.16087.1_3 - 0.0018 18.0 0.0 0.092 12.5 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.14 MSTRG.16087.1_3 - 0.0032 16.8 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.4 MSTRG.16087.1_3 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.4 MSTRG.16087.1_3 - 0.015 15.8 0.5 0.21 12.1 0.2 2.1 2 0 0 2 2 2 0 Homeodomain-like domain PAX PF00292.16 MSTRG.16087.1_3 - 0.081 12.7 0.0 0.097 12.4 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain DDE_3 PF13358.4 MSTRG.53112.1_3 - 2e-12 47.0 0.0 2.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease SeqA_N PF17206.1 MSTRG.27304.1_2 - 0.42 9.8 1.4 4 6.7 0.2 2.2 2 0 0 2 2 2 0 SeqA protein N-terminal domain DUF1031 PF06275.9 MSTRG.81572.1_1 - 0.04 14.0 0.1 0.058 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) ELO PF01151.16 MSTRG.26017.1_2 - 6.6e-31 107.6 8.1 7.2e-31 107.5 8.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Nucleos_tra2_C PF07662.11 MSTRG.26017.1_2 - 0.072 13.2 0.2 0.15 12.1 0.1 1.5 1 1 1 2 2 2 0 Na+ dependent nucleoside transporter C-terminus UQ_con PF00179.24 MSTRG.67333.2_1 - 1e-34 119.0 0.1 1.2e-34 118.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 MSTRG.67333.2_1 - 5.3e-05 22.8 0.0 5.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 MSTRG.67333.2_1 - 0.00022 21.4 0.1 0.00026 21.1 0.1 1.1 1 0 0 1 1 1 1 RWD domain UEV PF05743.11 MSTRG.67333.2_1 - 0.00085 19.0 0.1 0.0012 18.6 0.1 1.3 1 0 0 1 1 1 1 UEV domain zf-C2H2_4 PF13894.4 MSTRG.18354.1_1 - 5.5e-12 45.3 25.0 0.0012 19.4 2.3 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.18354.1_1 - 4.8e-08 33.0 12.8 0.12 12.6 1.1 4.2 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 MSTRG.18354.1_1 - 9.2e-07 28.4 15.7 0.00035 20.1 1.1 4.1 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-met PF12874.5 MSTRG.18354.1_1 - 4.4e-06 26.8 15.2 0.036 14.3 1.1 4.3 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.24 MSTRG.18354.1_1 - 1.6e-05 25.0 22.9 0.061 13.7 2.6 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.18354.1_1 - 0.00031 20.9 17.8 0.019 15.3 0.4 4.8 5 1 0 5 5 5 2 Zinc-finger double domain Zn-ribbon_8 PF09723.8 MSTRG.18354.1_1 - 0.0085 16.1 4.0 2.4 8.2 0.3 3.3 3 0 0 3 3 3 1 Zinc ribbon domain zinc_ribbon_9 PF14369.4 MSTRG.18354.1_1 - 0.018 15.2 3.4 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon zf-C2HC_2 PF13913.4 MSTRG.18354.1_1 - 0.022 14.6 1.1 0.022 14.6 1.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-LYAR PF08790.9 MSTRG.18354.1_1 - 0.22 11.3 0.0 0.22 11.3 0.0 3.7 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger XPA_N PF01286.16 MSTRG.18354.1_1 - 0.32 11.0 5.2 2.9 7.9 0.2 3.0 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_6 PF13912.4 MSTRG.18354.1_1 - 6.2 6.8 23.8 0.2 11.5 4.9 3.5 4 0 0 4 4 3 0 C2H2-type zinc finger UPF0231 PF06062.9 MSTRG.19530.1_2 - 0.13 12.4 0.0 8 6.6 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) Cas9-BH PF16593.3 MSTRG.19530.1_3 - 7.1 6.3 11.1 17 5.1 0.3 3.2 3 0 0 3 3 3 0 Bridge helix of CRISPR-associated endonuclease Cas9 HTH_32 PF13565.4 MSTRG.71959.1_1 - 0.0045 17.4 0.1 0.0062 17.0 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain TipAS PF07739.11 MSTRG.71959.1_1 - 0.045 14.2 0.0 0.056 13.8 0.0 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Luciferase_N PF05295.9 MSTRG.71959.1_2 - 0.088 12.7 0.2 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain SGS PF05002.13 MSTRG.72275.1_1 - 3.1e-32 110.4 0.9 7.6e-32 109.1 0.9 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.14 MSTRG.72275.1_1 - 5.4e-18 65.7 1.2 1.1e-17 64.6 1.2 1.6 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.15 MSTRG.72275.1_1 - 3.6e-08 32.8 0.6 0.025 14.6 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.26 MSTRG.72275.1_1 - 6.1e-06 25.7 0.4 0.0038 16.9 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.4 MSTRG.72275.1_1 - 0.027 14.0 0.3 0.15 11.7 0.1 2.1 1 1 1 2 2 2 0 TPR repeat TPR_19 PF14559.4 MSTRG.72275.1_1 - 0.037 14.4 0.5 0.15 12.5 0.3 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.4 MSTRG.72275.1_1 - 0.048 13.8 0.2 1.2 9.5 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.4 MSTRG.72275.1_1 - 0.11 13.1 0.4 0.49 11.0 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat L71 PF02448.13 MSTRG.29556.1_2 - 0.048 13.9 12.3 13 6.1 0.6 4.0 1 1 1 2 2 2 0 L71 family ANT PF03374.12 MSTRG.90371.1_2 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain TPR_1 PF00515.26 MSTRG.89198.1_2 - 6.4e-16 57.3 9.3 1.4e-08 34.0 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.15 MSTRG.89198.1_2 - 2.3e-15 55.2 8.9 1.8e-05 24.4 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.4 MSTRG.89198.1_2 - 1.3e-11 44.5 9.8 2e-08 34.2 3.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.5 MSTRG.89198.1_2 - 6.9e-11 42.1 6.3 1.5e-10 41.0 6.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.4 MSTRG.89198.1_2 - 8.7e-10 37.9 2.9 0.00013 21.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.4 MSTRG.89198.1_2 - 6.3e-09 36.2 0.0 0.00097 19.7 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.4 MSTRG.89198.1_2 - 5.2e-08 32.3 0.9 0.011 15.3 0.0 3.3 1 1 2 3 3 3 3 TPR repeat TPR_17 PF13431.4 MSTRG.89198.1_2 - 1.8e-07 30.9 1.6 0.013 15.7 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.4 MSTRG.89198.1_2 - 4.3e-07 29.4 2.3 0.2 11.6 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.4 MSTRG.89198.1_2 - 3.4e-06 27.3 1.1 7.3e-06 26.3 0.8 1.7 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_9 PF13371.4 MSTRG.89198.1_2 - 2.9e-05 24.0 0.3 5.4e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.4 MSTRG.89198.1_2 - 0.00047 20.5 1.2 5.7 7.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.4 MSTRG.89198.1_2 - 0.00085 19.8 0.3 0.035 14.8 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 MSTRG.89198.1_2 - 0.0046 16.8 0.3 0.072 13.0 0.1 2.4 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.4 MSTRG.89198.1_2 - 0.0059 16.3 4.8 0.36 10.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.12 MSTRG.89198.1_2 - 0.095 12.0 1.6 0.6 9.3 0.2 2.1 1 1 0 2 2 2 0 Coatomer epsilon subunit INSC_LBD PF16748.3 MSTRG.35587.1_1 - 0.24 10.7 2.1 13 5.2 0.1 2.3 1 1 1 2 2 2 0 Inscuteable LGN-binding domain DMAP_binding PF06464.9 MSTRG.114285.1_2 - 3.6e-17 63.1 0.6 6.2e-17 62.3 0.1 1.7 2 0 0 2 2 2 1 DMAP1-binding Domain RST PF12174.6 MSTRG.114285.1_2 - 0.07 13.0 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain AIG1 PF04548.14 MSTRG.106119.1_1 - 9.2e-10 38.1 0.4 3.3e-09 36.3 0.4 2.0 1 1 0 1 1 1 1 AIG1 family Septin PF00735.16 MSTRG.106119.1_1 - 2.5e-09 36.7 0.2 2.5e-09 36.7 0.2 2.0 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.21 MSTRG.106119.1_1 - 5.3e-09 36.0 0.0 1.7e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 MSTRG.106119.1_1 - 2.5e-05 24.1 1.7 3.9e-05 23.5 0.1 2.1 2 1 0 2 2 1 1 Protein of unknown function, DUF258 CENP-B_dimeris PF09026.8 MSTRG.106119.1_1 - 5.9e-05 23.3 1.1 0.00012 22.3 1.1 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain GTP_EFTU PF00009.25 MSTRG.106119.1_1 - 0.00016 21.2 0.1 0.00016 21.2 0.1 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.4 MSTRG.106119.1_1 - 0.00031 21.2 1.4 0.0011 19.4 1.4 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.25 MSTRG.106119.1_1 - 0.00055 20.3 1.0 0.0028 18.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.4 MSTRG.106119.1_1 - 0.0011 18.5 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.5 MSTRG.106119.1_1 - 0.0057 15.5 1.0 0.011 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.15 MSTRG.106119.1_1 - 0.0062 16.5 1.8 0.074 12.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 T2SSE PF00437.18 MSTRG.106119.1_1 - 0.045 12.7 1.0 0.062 12.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.4 MSTRG.106119.1_1 - 0.054 13.6 0.1 0.28 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF4446 PF14584.4 MSTRG.106119.1_1 - 0.091 12.6 2.0 2.1 8.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) AAA_16 PF13191.4 MSTRG.106119.1_1 - 0.17 12.1 0.6 1.4 9.2 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Nop53 PF07767.9 MSTRG.106119.1_1 - 0.29 10.4 8.0 0.42 9.9 8.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FeoB_N PF02421.16 MSTRG.106119.1_1 - 0.44 9.9 2.6 20 4.6 0.1 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B Utp11 PF03998.11 MSTRG.106119.1_1 - 0.81 9.4 7.9 0.74 9.5 6.4 1.6 2 0 0 2 2 2 0 Utp11 protein Dynamin_N PF00350.21 MSTRG.106119.1_1 - 1.1 9.2 11.7 3.8 7.4 0.1 3.7 2 2 1 3 3 3 0 Dynamin family FH2 PF02181.21 MSTRG.57902.1_3 - 6.5e-47 160.3 2.5 6.5e-47 160.3 2.5 1.4 2 0 0 2 2 2 1 Formin Homology 2 Domain DAG_kinase_N PF14513.4 MSTRG.57902.1_3 - 0.029 14.5 4.6 0.044 13.8 4.6 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus MIF4G PF02854.17 MSTRG.22118.1_3 - 4.3e-36 124.4 2.8 4.7e-36 124.3 2.8 1.0 1 0 0 1 1 1 1 MIF4G domain TFIIF_alpha PF05793.10 MSTRG.139614.1_1 - 6.6 5.1 37.0 10 4.5 37.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DEAD PF00270.27 MSTRG.7985.1_2 - 6.9e-21 74.7 0.2 8.2e-21 74.4 0.2 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBF_like PF13593.4 MSTRG.7985.1_2 - 0.00018 20.8 0.0 0.00018 20.8 0.0 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) ResIII PF04851.13 MSTRG.7985.1_2 - 0.0017 18.2 0.1 0.0018 18.2 0.1 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit YbjM PF11045.6 MSTRG.7985.1_2 - 0.072 13.1 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae zf-C2H2_11 PF16622.3 MSTRG.57270.1_3 - 0.09 12.4 2.1 0.17 11.6 2.1 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type Phosphorylase PF00343.18 MSTRG.101986.1_3 - 1.8e-58 198.3 1.0 1.9e-58 198.2 1.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DicB PF05358.9 MSTRG.101986.1_3 - 0.029 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 DicB protein zf-C2H2_2 PF12756.5 MSTRG.56521.1_3 - 0.00078 19.6 1.1 0.001 19.2 1.1 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.6 MSTRG.56521.1_3 - 0.026 14.7 5.2 0.042 14.1 5.2 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding T3SS_needle_F PF09392.8 MSTRG.124143.1_1 - 0.00087 19.4 3.3 0.56 10.4 0.2 2.2 1 1 1 2 2 2 2 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF SF-assemblin PF06705.9 MSTRG.124143.1_1 - 0.0067 15.7 1.9 0.012 14.9 1.9 1.4 1 1 0 1 1 1 1 SF-assemblin/beta giardin DASH_Duo1 PF08651.8 MSTRG.124143.1_1 - 0.04 13.6 5.9 3.5 7.4 1.9 2.8 1 1 1 2 2 2 0 DASH complex subunit Duo1 HTH_Mga PF08280.9 MSTRG.124143.1_1 - 0.13 12.2 0.1 94 3.0 0.0 2.9 1 1 2 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Baculo_PEP_C PF04513.10 MSTRG.124143.1_1 - 0.38 10.7 17.3 1.1 9.2 17.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SSPI PF14098.4 MSTRG.124143.1_1 - 0.81 9.8 4.1 20 5.3 0.4 2.7 1 1 2 3 3 3 0 Small, acid-soluble spore protein I Yippee-Mis18 PF03226.12 MSTRG.132199.1_3 - 0.013 15.5 2.4 0.41 10.7 0.1 2.1 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TPR_2 PF07719.15 MSTRG.115918.1_2 - 0.035 14.1 0.1 0.035 14.1 0.1 1.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.26 MSTRG.115918.1_2 - 0.36 10.6 1.9 0.59 9.9 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HLH PF00010.24 MSTRG.52847.1_1 - 5.5e-18 64.5 0.6 5.5e-18 64.5 0.6 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TMEM100 PF16311.3 MSTRG.74999.1_2 - 0.085 12.3 1.0 0.17 11.3 1.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 Fucokinase PF07959.10 MSTRG.125188.1_3 - 9.8e-17 60.9 0.9 1e-16 60.9 0.9 1.0 1 0 0 1 1 1 1 L-fucokinase Lactamase_B PF00753.25 MSTRG.66242.1_1 - 2.2e-16 60.3 0.4 9.2e-15 55.0 0.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.5 MSTRG.66242.1_1 - 0.0034 16.8 0.1 0.0073 15.7 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HTH_23 PF13384.4 MSTRG.75683.1_3 - 0.0031 17.1 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.4 MSTRG.75683.1_3 - 0.0053 16.4 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain B56 PF01603.18 MSTRG.131831.1_2 - 8.5e-91 304.8 0.4 9.4e-91 304.7 0.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.5 MSTRG.131831.1_2 - 0.084 12.7 0.3 0.26 11.1 0.1 1.8 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Herpes_capsid PF06112.9 MSTRG.131831.1_3 - 0.91 9.4 7.8 1.2 9.0 7.8 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RVT_1 PF00078.25 MSTRG.87421.1_1 - 8.7e-20 71.0 0.0 2.4e-18 66.4 0.1 2.5 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cyt_b-c1_8 PF10890.6 MSTRG.87421.1_1 - 0.021 15.1 0.0 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 Sirohm_synth_M PF14824.4 MSTRG.126504.1_2 - 0.14 11.5 0.9 0.23 10.8 0.9 1.3 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Presenilin PF01080.15 MSTRG.106312.1_1 - 3.6e-47 160.9 0.1 4.5e-47 160.6 0.1 1.1 1 0 0 1 1 1 1 Presenilin ABC2_membrane_2 PF12679.5 MSTRG.106312.1_1 - 0.032 13.4 1.5 0.043 13.0 1.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein D123 PF07065.12 MSTRG.99684.1_1 - 3.9e-40 137.8 0.3 4.3e-40 137.6 0.3 1.0 1 0 0 1 1 1 1 D123 DUF2793 PF10983.6 MSTRG.1044.1_3 - 0.014 15.1 0.0 0.034 13.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) DUF2617 PF10936.6 MSTRG.1044.1_3 - 0.061 13.3 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2617 HTH_38 PF13936.4 MSTRG.26921.1_3 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sushi PF00084.18 MSTRG.112454.5_2 - 7.9e-10 39.1 0.9 1.7e-09 38.0 0.9 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) MGC-24 PF05283.9 MSTRG.112454.5_2 - 1.6e-06 28.5 3.2 2.1e-06 28.1 3.2 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.4 MSTRG.112454.5_2 - 5.9e-06 26.1 0.4 7.8e-06 25.7 0.4 1.1 1 0 0 1 1 1 1 TMEM154 protein family Mucin PF01456.15 MSTRG.112454.5_2 - 0.00066 19.6 23.8 0.00079 19.3 23.8 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF4366 PF14283.4 MSTRG.112454.5_2 - 0.0015 17.9 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Mid2 PF04478.10 MSTRG.112454.5_2 - 0.0079 15.9 2.8 0.011 15.4 2.8 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rifin_STEVOR PF02009.14 MSTRG.112454.5_2 - 0.023 14.4 0.0 0.027 14.2 0.0 1.0 1 0 0 1 1 1 0 Rifin/stevor family DUF3827 PF12877.5 MSTRG.112454.5_2 - 0.081 11.1 0.7 0.11 10.7 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) Syndecan PF01034.18 MSTRG.112454.5_2 - 0.21 11.4 1.4 0.35 10.7 1.4 1.3 1 0 0 1 1 1 0 Syndecan domain Sporozoite_P67 PF05642.9 MSTRG.112454.5_2 - 0.35 8.8 5.4 0.37 8.7 5.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.10 MSTRG.112454.5_2 - 1.3 6.8 11.9 1.5 6.6 11.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Podoplanin PF05808.9 MSTRG.112454.5_2 - 1.8 8.5 13.1 3.7 7.5 13.2 1.3 1 1 0 1 1 1 0 Podoplanin FSA_C PF10479.7 MSTRG.112454.5_2 - 2.6 5.9 8.6 2.9 5.8 8.6 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus EF-hand_4 PF12763.5 MSTRG.52002.1_1 - 7.3e-20 70.7 0.0 9.4e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.30 MSTRG.52002.1_1 - 0.00081 18.6 0.1 0.0013 18.0 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.4 MSTRG.52002.1_1 - 0.0012 18.5 0.2 0.0022 17.6 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.4 MSTRG.52002.1_1 - 0.041 14.2 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.4 MSTRG.52002.1_1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.4 MSTRG.52002.1_1 - 0.069 12.6 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 EF hand zf-Tim10_DDP PF02953.13 MSTRG.23095.1_1 - 8.2e-16 57.3 6.8 8.2e-16 57.3 6.8 1.8 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DUF2116 PF09889.7 MSTRG.23095.1_1 - 0.08 12.8 1.2 0.18 11.7 1.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3381 PF11861.6 MSTRG.17432.1_3 - 4.1e-20 72.1 51.5 1.3e-18 67.3 43.0 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3381) rRNA_processing PF08524.9 MSTRG.17432.1_3 - 0.25 11.2 37.2 0.19 11.6 29.8 2.1 2 0 0 2 2 2 0 rRNA processing BUD22 PF09073.8 MSTRG.17432.1_3 - 0.47 9.6 28.5 0.68 9.1 28.5 1.2 1 0 0 1 1 1 0 BUD22 Dsh_C PF12316.6 MSTRG.17432.1_3 - 0.75 10.1 2.0 1.2 9.4 2.0 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SOBP PF15279.4 MSTRG.17432.1_3 - 1.1 9.7 2.6 1.7 9.0 2.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Tox-ODYAM1 PF15642.4 MSTRG.17432.1_3 - 1.4 7.7 15.2 2.5 6.9 15.2 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus eIF3_subunit PF08597.8 MSTRG.17432.1_3 - 5 6.8 42.1 0.38 10.5 25.6 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit YjgP_YjgQ PF03739.12 MSTRG.17432.1_3 - 7.5 5.2 5.2 11 4.6 5.2 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family UcrQ PF02939.14 MSTRG.38047.1_2 - 0.16 11.8 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 UcrQ family DUF1652 PF07865.9 MSTRG.139676.1_2 - 0.1 12.3 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) IGFBP PF00219.16 MSTRG.41463.1_2 - 3.6e-09 37.0 21.0 3.6e-09 37.0 21.0 2.6 2 1 0 2 2 2 1 Insulin-like growth factor binding protein Colipase_C PF02740.12 MSTRG.41463.1_2 - 0.0023 17.9 3.0 0.0023 17.9 3.0 3.0 3 0 0 3 3 3 1 Colipase, C-terminal domain DUF3265 PF11665.6 MSTRG.41463.1_3 - 0.27 11.4 3.4 0.59 10.3 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) zf-H2C2_2 PF13465.4 MSTRG.81719.1_1 - 1.6e-10 40.8 64.3 2.1e-05 24.6 5.5 8.0 8 2 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.81719.1_1 - 1.1e-05 25.4 2.7 1.1e-05 25.4 2.7 4.5 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 MSTRG.81719.1_1 - 0.00012 21.8 11.8 0.0016 18.2 3.3 5.0 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_4 PF13894.4 MSTRG.81719.1_1 - 0.00039 20.9 1.5 0.00039 20.9 1.5 5.3 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2HE PF16278.3 MSTRG.81719.1_1 - 0.0012 19.2 16.7 0.096 13.0 0.6 3.9 4 0 0 4 4 4 3 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.8 MSTRG.81719.1_1 - 0.0069 16.3 13.4 1.2 9.2 0.1 4.0 4 0 0 4 4 4 3 Zinc ribbon domain zf-met PF12874.5 MSTRG.81719.1_1 - 0.037 14.3 1.2 0.037 14.3 1.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Fer4_17 PF13534.4 MSTRG.81719.1_1 - 0.25 11.8 9.1 0.1 13.0 3.5 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain zinc-ribbons_6 PF07191.10 MSTRG.81719.1_1 - 2.7 7.9 12.8 5.2 7.0 2.1 3.7 3 1 1 4 4 4 0 zinc-ribbons FYVE PF01363.19 MSTRG.81719.1_1 - 2.8 8.0 21.3 0.61 10.1 4.0 3.5 2 1 0 3 3 3 0 FYVE zinc finger FYDLN_acid PF09538.8 MSTRG.81719.1_1 - 3.3 8.3 7.2 8.1 7.0 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-met PF12874.5 MSTRG.81719.1_2 - 0.045 14.0 0.2 0.088 13.1 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.24 MSTRG.81719.1_2 - 0.083 13.3 1.1 0.18 12.2 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.81719.1_3 - 1.2e-18 66.5 34.5 1.1e-07 31.9 5.8 4.9 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_6 PF13912.4 MSTRG.81719.1_3 - 1.2e-06 28.2 25.5 0.078 12.8 1.0 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.24 MSTRG.81719.1_3 - 8.3e-06 25.9 30.3 0.0046 17.2 1.2 5.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2HE PF16278.3 MSTRG.81719.1_3 - 0.00066 20.0 20.6 0.5 10.7 0.7 4.2 3 1 1 4 4 4 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.4 MSTRG.81719.1_3 - 0.00095 19.7 28.3 0.12 13.1 3.2 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger C1_1 PF00130.20 MSTRG.81719.1_3 - 0.0015 18.3 11.2 0.97 9.2 3.7 4.1 2 1 2 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-AN1 PF01428.14 MSTRG.81719.1_3 - 0.052 13.6 14.5 9.8 6.3 0.2 4.3 4 0 0 4 4 4 0 AN1-like Zinc finger zf-trcl PF13451.4 MSTRG.81719.1_3 - 0.087 12.6 9.5 3.2 7.6 2.4 3.9 3 1 0 3 3 3 0 Probable zinc-ribbon domain FYVE PF01363.19 MSTRG.81719.1_3 - 0.11 12.5 14.0 3.5 7.7 0.0 3.4 2 1 1 3 3 3 0 FYVE zinc finger Zn-ribbon_8 PF09723.8 MSTRG.81719.1_3 - 0.18 11.8 18.3 1.9 8.6 4.1 4.3 3 2 1 4 4 4 0 Zinc ribbon domain zf-C2H2_11 PF16622.3 MSTRG.81719.1_3 - 1.2 8.8 18.3 2.8 7.7 0.1 4.7 5 0 0 5 5 5 0 zinc-finger C2H2-type XPA_N PF01286.16 MSTRG.81719.1_3 - 1.4 8.9 9.5 25 4.9 0.1 4.2 4 0 0 4 4 4 0 XPA protein N-terminal DZR PF12773.5 MSTRG.81719.1_3 - 1.8 8.5 17.1 11 6.0 0.3 3.4 2 1 0 2 2 2 0 Double zinc ribbon DUF2256 PF10013.7 MSTRG.81719.1_3 - 7 6.7 12.3 24 5.0 0.1 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc-ribbons_6 PF07191.10 MSTRG.81719.1_3 - 7.5 6.5 13.8 2.8 7.9 2.4 3.6 2 1 2 4 4 4 0 zinc-ribbons Mor PF08765.9 MSTRG.131793.1_3 - 0.042 13.7 0.1 0.058 13.3 0.1 1.1 1 0 0 1 1 1 0 Mor transcription activator family MARCKS PF02063.15 MSTRG.127051.1_2 - 1.2e-12 48.3 56.7 1.4e-10 41.5 56.7 2.1 1 1 0 1 1 1 1 MARCKS family RFXA_RFXANK_bdg PF15289.4 MSTRG.127051.1_2 - 0.54 10.5 2.9 0.91 9.7 2.9 1.2 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Rib PF08428.8 MSTRG.106992.1_2 - 1.2 9.0 4.1 10 6.1 1.9 3.1 1 1 1 2 2 2 0 Rib/alpha-like repeat Ribosomal_L7Ae PF01248.24 MSTRG.140952.1_2 - 3.8e-25 87.3 0.0 4.5e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Myosin_tail_1 PF01576.17 MSTRG.20535.1_3 - 2.4e-27 95.1 42.8 2.7e-27 95.0 42.8 1.0 1 0 0 1 1 1 1 Myosin tail Alanine_zipper PF11839.6 MSTRG.20535.1_3 - 6.3e-05 23.0 27.1 0.012 15.8 6.3 4.0 1 1 3 4 4 4 2 Alanine-zipper, major outer membrane lipoprotein Tropomyosin PF00261.18 MSTRG.20535.1_3 - 0.0012 18.1 45.6 0.0033 16.7 6.9 3.2 1 1 2 3 3 3 3 Tropomyosin Trimer_CC PF08954.9 MSTRG.20535.1_3 - 0.0019 17.6 1.0 0.0019 17.6 1.0 3.8 3 0 0 3 3 3 1 Trimerisation motif Reo_sigmaC PF04582.10 MSTRG.20535.1_3 - 0.013 14.8 9.9 0.55 9.4 4.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Rootletin PF15035.4 MSTRG.20535.1_3 - 0.013 15.5 3.9 0.013 15.5 3.9 3.5 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion BRE1 PF08647.9 MSTRG.20535.1_3 - 0.013 15.4 35.4 0.16 11.9 12.8 2.9 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Laminin_II PF06009.10 MSTRG.20535.1_3 - 0.048 13.5 24.4 0.27 11.1 6.4 3.0 1 1 2 3 3 3 0 Laminin Domain II CALCOCO1 PF07888.9 MSTRG.20535.1_3 - 0.077 11.4 33.3 0.092 11.2 33.3 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fib_alpha PF08702.8 MSTRG.20535.1_3 - 0.13 12.3 24.3 0.018 15.1 11.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MAD PF05557.11 MSTRG.20535.1_3 - 0.14 10.3 37.8 0.32 9.2 25.1 2.4 1 1 2 3 3 3 0 Mitotic checkpoint protein ATG16 PF08614.9 MSTRG.20535.1_3 - 0.18 11.8 38.8 0.44 10.6 18.4 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1647 PF07801.9 MSTRG.20535.1_3 - 0.2 11.3 4.2 0.18 11.5 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1647) IncA PF04156.12 MSTRG.20535.1_3 - 0.38 10.4 34.1 0.081 12.6 10.9 2.5 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.10 MSTRG.20535.1_3 - 0.42 10.5 39.8 1 9.3 20.6 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.5 MSTRG.20535.1_3 - 0.6 10.1 42.8 0.12 12.3 16.1 3.2 1 1 2 3 3 3 0 Tropomyosin like APG6 PF04111.10 MSTRG.20535.1_3 - 0.76 9.0 35.9 0.81 8.9 17.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ALMT PF11744.6 MSTRG.20535.1_3 - 0.82 8.3 16.8 1.1 7.8 16.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter PAPS_reduct PF01507.17 MSTRG.20535.1_3 - 0.84 9.5 9.0 1.1 9.1 7.7 1.8 1 1 1 2 2 2 0 Phosphoadenosine phosphosulfate reductase family LPP PF04728.11 MSTRG.20535.1_3 - 0.9 9.8 22.2 1.2 9.4 1.3 4.6 4 1 1 5 5 4 0 Lipoprotein leucine-zipper DUF745 PF05335.11 MSTRG.20535.1_3 - 1.6 8.3 31.9 2.4 7.7 15.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Leu_zip PF15294.4 MSTRG.20535.1_3 - 1.7 7.9 32.6 6.2 6.1 13.1 2.6 1 1 0 2 2 2 0 Leucine zipper BRI3BP PF14965.4 MSTRG.20535.1_3 - 1.8 7.9 10.3 5.9 6.2 0.5 3.2 3 1 0 3 3 3 0 Negative regulator of p53/TP53 DUF948 PF06103.9 MSTRG.20535.1_3 - 2 8.6 18.0 4.9 7.3 0.7 4.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.10 MSTRG.20535.1_3 - 2.3 8.2 9.7 7.7 6.4 5.7 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tn7_Tnp_TnsA_C PF08721.9 MSTRG.20535.1_3 - 2.7 8.5 7.0 1.8 9.1 0.8 3.1 1 1 1 3 3 3 0 TnsA endonuclease C terminal DUF3450 PF11932.6 MSTRG.20535.1_3 - 3.1 6.9 28.1 0.63 9.2 8.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.10 MSTRG.20535.1_3 - 3.9 7.3 25.4 0.39 10.6 5.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) T3SSipB PF16535.3 MSTRG.20535.1_3 - 5.1 7.4 24.0 3.1 8.1 2.8 3.0 1 1 2 3 3 3 0 Type III cell invasion protein SipB COG2 PF06148.9 MSTRG.20535.1_3 - 5.3 7.0 27.4 0.74 9.8 6.7 3.2 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.4 MSTRG.20535.1_3 - 5.8 5.3 26.0 8.6 4.7 26.0 1.3 1 0 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.3 MSTRG.20535.1_3 - 6.1 6.9 22.3 0.6 10.1 1.4 4.1 1 1 3 4 4 4 0 TolA binding protein trimerisation DUF812 PF05667.9 MSTRG.20535.1_3 - 6.6 5.4 33.2 16 4.1 33.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.7 MSTRG.20535.1_3 - 7.2 6.5 39.7 14 5.6 26.4 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.4 MSTRG.20535.1_3 - 8 5.9 38.6 15 5.0 10.5 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.19 MSTRG.105900.1_3 - 1.9e-09 37.3 15.7 3.4e-09 36.5 15.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 MSTRG.105900.1_3 - 5e-07 29.6 16.6 8.9e-07 28.8 16.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 MSTRG.105900.1_3 - 4.6e-05 23.7 13.2 8e-05 23.0 13.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.13 MSTRG.105900.1_3 - 0.77 9.4 3.5 1.6 8.4 3.5 1.4 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.12 MSTRG.105900.1_3 - 1.1 8.9 7.3 1.8 8.2 7.3 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.10 MSTRG.105900.1_3 - 3 7.0 8.6 4.5 6.4 8.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.13 MSTRG.105900.1_3 - 9.1 6.0 9.2 15 5.2 9.2 1.2 1 0 0 1 1 1 0 Mnd1 family Peptidase_C1 PF00112.21 MSTRG.18322.1_3 - 5e-11 43.0 5.2 7.1e-11 42.5 5.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Ribophorin_II PF05817.12 MSTRG.39084.1_3 - 2.3e-110 369.9 3.0 3e-110 369.6 3.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II HMG_box_2 PF09011.8 MSTRG.46373.1_1 - 2.2e-38 130.5 4.9 2.9e-26 91.7 2.8 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.17 MSTRG.46373.1_1 - 2.4e-37 127.0 3.2 7.9e-21 74.1 0.1 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box Cwf_Cwc_15 PF04889.10 MSTRG.46373.1_1 - 0.017 14.7 7.0 0.026 14.1 7.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YABBY PF04690.11 MSTRG.46373.1_1 - 0.035 14.5 0.1 0.035 14.5 0.1 2.0 2 0 0 2 2 2 0 YABBY protein HMG_box_5 PF14887.4 MSTRG.46373.1_1 - 0.049 13.5 5.6 0.24 11.3 1.9 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box 5 NOA36 PF06524.10 MSTRG.46373.1_1 - 1.1 8.5 13.6 1.9 7.7 13.6 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.11 MSTRG.46373.1_1 - 6.4 4.6 11.8 8.5 4.2 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sdh_cyt PF01127.20 MSTRG.75325.1_3 - 0.059 13.3 0.2 0.073 13.0 0.2 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit B56 PF01603.18 MSTRG.123544.1_3 - 5.8e-198 657.8 10.8 7e-198 657.5 10.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) AF-4 PF05110.11 MSTRG.28536.1_1 - 5.7e-57 193.6 48.1 6.4e-57 193.4 48.1 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein LicD PF04991.11 MSTRG.28536.1_1 - 1.5 8.8 6.6 0.2 11.6 2.3 1.8 2 1 0 2 2 2 0 LicD family zf-C2H2 PF00096.24 MSTRG.23670.1_2 - 0.00047 20.3 4.0 0.0013 19.0 4.0 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.23670.1_2 - 0.0018 18.8 2.7 0.005 17.4 2.7 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.4 MSTRG.23670.1_3 - 3.7e-09 36.5 10.6 6.6e-06 26.2 0.7 4.3 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.23670.1_3 - 3.8e-09 36.4 35.0 0.00032 20.9 4.5 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.23670.1_3 - 2.9e-05 24.4 31.4 0.013 16.1 2.3 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.23670.1_3 - 0.00016 21.4 1.3 0.00016 21.4 1.3 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.23670.1_3 - 0.0006 19.9 15.7 0.16 12.2 1.4 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.14 MSTRG.23670.1_3 - 0.0028 17.6 11.1 0.088 12.9 1.2 3.9 3 0 0 3 3 3 1 AN1-like Zinc finger Zn-ribbon_8 PF09723.8 MSTRG.23670.1_3 - 0.0051 16.8 5.9 0.1 12.6 1.4 2.7 2 0 0 2 2 2 1 Zinc ribbon domain zf-met PF12874.5 MSTRG.23670.1_3 - 0.058 13.7 0.9 0.058 13.7 0.9 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4379 PF14311.4 MSTRG.23670.1_3 - 0.13 12.5 1.5 0.34 11.2 0.1 2.3 2 0 0 2 2 2 0 Probable Zinc-ribbon domain GAGA PF09237.9 MSTRG.23670.1_3 - 0.4 10.4 4.6 0.3 10.8 0.2 2.8 2 1 1 3 3 3 0 GAGA factor C1_4 PF07975.10 MSTRG.23670.1_3 - 2.4 8.3 20.0 1.2 9.4 6.0 3.6 3 1 0 3 3 3 0 TFIIH C1-like domain HTH_38 PF13936.4 MSTRG.68323.1_3 - 1.6e-05 24.4 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.68323.1_3 - 0.025 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Ribosomal_S13_N PF08069.10 MSTRG.68323.1_3 - 0.051 13.5 1.9 0.2 11.6 0.1 2.4 2 1 1 3 3 3 0 Ribosomal S13/S15 N-terminal domain DUF4269 PF14091.4 MSTRG.68323.1_3 - 0.14 12.3 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) RVT_1 PF00078.25 MSTRG.34029.1_3 - 0.0011 18.4 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1068 PF06364.10 MSTRG.60047.1_3 - 0.055 13.2 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Cecropin PF00272.17 MSTRG.142459.1_2 - 0.47 10.4 7.6 80 3.2 0.0 5.0 6 0 0 6 6 6 0 Cecropin family DUF3252 PF11623.6 MSTRG.142459.1_2 - 7.3 6.2 7.4 17 5.0 0.0 4.4 6 0 0 6 6 6 0 Protein of unknown function (DUF3252) DUF2774 PF11242.6 MSTRG.142459.1_3 - 0.0092 16.0 14.8 9.9 6.3 0.2 5.4 1 1 4 5 5 5 4 Protein of unknown function (DUF2774) COE1_DBD PF16422.3 MSTRG.142459.1_3 - 3.7 6.7 8.6 3.7 6.7 0.5 2.5 1 1 2 3 3 3 0 Transcription factor COE1 DNA-binding domain Arfaptin PF06456.11 MSTRG.119551.1_3 - 0.0027 17.2 0.3 0.0033 16.9 0.3 1.1 1 0 0 1 1 1 1 Arfaptin-like domain Septin PF00735.16 MSTRG.129137.1_2 - 2e-96 322.4 3.2 2e-96 322.4 3.2 1.7 2 0 0 2 2 2 1 Septin AAA_22 PF13401.4 MSTRG.129137.1_2 - 0.00045 20.4 0.3 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.21 MSTRG.129137.1_2 - 0.00058 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.11 MSTRG.129137.1_2 - 0.0016 18.5 0.1 0.0045 17.1 0.0 1.8 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.4 MSTRG.129137.1_2 - 0.0018 18.6 0.1 0.009 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.14 MSTRG.129137.1_2 - 0.0019 18.0 0.0 0.45 10.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 MSTRG.129137.1_2 - 0.0043 16.5 2.2 1.1 8.6 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.4 MSTRG.129137.1_2 - 0.017 14.7 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2959 PF11172.6 MSTRG.129137.1_2 - 0.018 15.0 4.5 0.036 13.9 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) AIG1 PF04548.14 MSTRG.129137.1_2 - 0.026 13.7 0.0 0.026 13.7 0.0 1.6 2 0 0 2 2 2 0 AIG1 family Ras PF00071.20 MSTRG.129137.1_2 - 0.041 13.3 0.1 0.1 12.1 0.1 1.7 1 0 0 1 1 1 0 Ras family DUF87 PF01935.15 MSTRG.129137.1_2 - 0.25 11.2 4.7 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Atg14 PF10186.7 MSTRG.129137.1_2 - 0.34 9.8 7.6 0.74 8.7 7.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fzo_mitofusin PF04799.11 MSTRG.129137.1_2 - 3.6 6.9 9.8 0.7 9.3 6.2 1.7 2 0 0 2 2 2 0 fzo-like conserved region Exonuc_VII_L PF02601.13 MSTRG.129137.1_2 - 9.8 5.5 12.9 3 7.2 8.7 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Integrin_alpha PF00357.18 MSTRG.28161.1_3 - 0.07 13.0 0.9 0.19 11.7 0.9 1.7 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Integrin_alpha2 PF08441.10 MSTRG.28161.1_3 - 0.084 11.6 1.8 0.11 11.3 1.8 1.1 1 0 0 1 1 1 0 Integrin alpha DUF3328 PF11807.6 MSTRG.28161.1_3 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4381 PF14316.4 MSTRG.28161.1_3 - 0.098 12.8 0.3 0.19 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PYRIN PF02758.14 MSTRG.45113.2_2 - 7.7e-19 67.5 0.0 1.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain CARD PF00619.19 MSTRG.45113.2_2 - 6.1e-16 58.1 0.1 2.3e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Caspase recruitment domain HSR PF03172.11 MSTRG.45113.2_2 - 0.075 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 HSR domain Tmemb_161AB PF10268.7 MSTRG.20515.1_2 - 1.2e-27 96.6 3.6 1.3e-27 96.6 3.6 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Kunitz_BPTI PF00014.21 MSTRG.25037.1_3 - 2.1e-35 120.6 20.5 7.2e-18 64.4 7.8 2.5 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain MANEC PF07502.12 MSTRG.25037.1_3 - 3.8e-12 46.2 1.4 3.8e-12 46.2 1.4 2.3 2 0 0 2 2 2 1 MANEC domain DAN PF03045.13 MSTRG.4292.1_1 - 8.6e-25 86.8 8.1 1.4e-24 86.1 8.1 1.3 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.20 MSTRG.4292.1_1 - 7.7e-05 22.8 8.9 0.00013 22.1 8.9 1.3 1 0 0 1 1 1 1 Cystine-knot domain SelP_N PF04592.12 MSTRG.4292.1_1 - 0.74 9.0 9.5 1.1 8.5 9.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1891 PF09004.8 MSTRG.58343.1_3 - 0.00016 21.1 0.2 0.00016 21.1 0.2 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1891) DUF4455 PF14643.4 MSTRG.58343.1_3 - 0.015 14.0 1.0 0.017 13.8 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) HTH_30 PF13556.4 MSTRG.58343.1_3 - 0.029 14.0 1.3 0.051 13.3 1.3 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain PI3K_p85B PF02192.14 MSTRG.81632.1_2 - 6.5e-30 102.5 0.3 1.1e-29 101.8 0.3 1.4 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.16 MSTRG.81632.1_2 - 8.5e-22 77.2 0.5 7.4e-19 67.8 0.2 2.2 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain RVT_1 PF00078.25 MSTRG.117849.1_3 - 9.9e-16 57.8 0.0 1.4e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1891 PF09004.8 MSTRG.117849.1_3 - 1.1e-13 50.4 1.2 2.1e-13 49.5 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1891) DUF1133 PF06576.9 MSTRG.117849.1_3 - 0.063 12.5 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) zf-H2C2_2 PF13465.4 MSTRG.94858.1_2 - 4.8e-33 112.0 44.0 3.4e-09 36.6 3.1 6.1 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.94858.1_2 - 8.4e-19 66.8 43.5 7.6e-06 26.0 0.6 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.94858.1_2 - 1.9e-15 56.1 41.2 0.00038 20.9 0.7 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-LYAR PF08790.9 MSTRG.94858.1_2 - 4.8e-07 29.4 21.8 0.076 12.8 0.6 5.5 5 0 0 5 5 5 4 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.6 MSTRG.94858.1_2 - 3.2e-05 24.0 22.5 0.17 12.1 1.0 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 MSTRG.94858.1_2 - 4.5e-05 23.0 19.8 0.36 10.5 0.4 4.4 4 0 0 4 4 4 4 zinc-finger C2H2-type zf-C2HE PF16278.3 MSTRG.94858.1_2 - 0.0008 19.7 28.9 0.49 10.8 1.8 5.0 1 1 3 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.10 MSTRG.94858.1_2 - 0.0032 17.6 15.0 0.082 13.1 2.4 4.1 2 1 1 4 4 4 1 TFIIH C1-like domain zf-C2H2_6 PF13912.4 MSTRG.94858.1_2 - 0.015 15.1 1.5 0.015 15.1 1.5 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger FYDLN_acid PF09538.8 MSTRG.94858.1_2 - 0.034 14.7 6.2 8.8 6.9 0.2 3.8 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_9 PF14369.4 MSTRG.94858.1_2 - 0.046 13.8 16.5 7.8 6.7 0.2 5.3 5 0 0 5 5 5 0 zinc-ribbon Elf1 PF05129.11 MSTRG.94858.1_2 - 0.068 13.1 21.7 0.67 9.9 3.9 3.7 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.10 MSTRG.94858.1_2 - 0.078 13.1 23.9 0.25 11.5 2.6 3.6 2 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.4 MSTRG.94858.1_2 - 0.11 12.3 14.3 0.84 9.5 1.5 4.2 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.17 MSTRG.94858.1_2 - 0.13 12.2 13.1 2.8 7.9 5.5 3.1 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.3 MSTRG.94858.1_2 - 0.22 12.2 11.6 2.1 9.0 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbon family PyrI_C PF02748.13 MSTRG.94858.1_2 - 0.76 9.6 10.8 8.6 6.2 0.1 4.2 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_10 PF10058.7 MSTRG.94858.1_2 - 1.1 9.0 15.0 0.58 9.8 1.4 3.9 3 1 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.8 MSTRG.94858.1_2 - 1.1 9.3 21.4 0.49 10.4 4.7 3.8 1 1 2 4 4 4 0 Zinc ribbon domain zf-met PF12874.5 MSTRG.94858.1_2 - 1.8 8.9 34.3 0.3 11.4 2.3 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type BolA PF01722.16 MSTRG.94858.1_2 - 2 8.6 7.7 3.2 8.0 1.2 3.6 2 1 2 4 4 4 0 BolA-like protein GAGA PF09237.9 MSTRG.94858.1_2 - 3.4 7.4 9.5 0.69 9.6 1.8 3.1 1 1 3 4 4 4 0 GAGA factor zf-CHY PF05495.10 MSTRG.94858.1_2 - 5.8 7.4 27.5 2 8.9 5.5 3.9 1 1 3 4 4 4 0 CHY zinc finger zf-BED PF02892.13 MSTRG.94858.1_2 - 7.2 6.6 30.2 0.22 11.5 7.3 4.7 1 1 3 4 4 4 0 BED zinc finger zf-AN1 PF01428.14 MSTRG.94858.1_2 - 9.3 6.4 29.2 3.9 7.6 0.1 5.4 3 1 2 5 5 5 0 AN1-like Zinc finger Fim-adh_lectin PF09222.8 MSTRG.94858.1_3 - 0.043 13.2 0.1 0.067 12.6 0.1 1.2 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain Rab5-bind PF09311.9 MSTRG.89761.1_2 - 5.7e-33 114.5 16.5 6.6e-33 114.3 16.5 1.0 1 0 0 1 1 1 1 Rabaptin-like protein FPP PF05911.9 MSTRG.89761.1_2 - 0.033 12.3 12.1 0.038 12.1 12.1 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Sec5 PF15469.4 MSTRG.89761.1_2 - 0.084 12.5 4.1 0.11 12.2 4.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 APG6 PF04111.10 MSTRG.89761.1_2 - 5.8 6.1 11.8 6.5 5.9 11.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1031 PF06275.9 MSTRG.64505.1_2 - 0.015 15.4 0.3 0.024 14.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) RNA_pol_A_bac PF01000.24 MSTRG.60759.1_1 - 2.1e-16 60.2 0.0 3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.22 MSTRG.60759.1_1 - 9.2e-11 40.9 0.0 1.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GoLoco PF02188.15 MSTRG.125696.1_3 - 3e-06 26.5 1.0 4.3e-06 26.0 1.0 1.3 1 0 0 1 1 1 1 GoLoco motif NUC205 PF08168.9 MSTRG.36975.1_2 - 0.24 10.8 3.4 0.35 10.3 0.8 2.1 1 1 1 2 2 2 0 NUC205 domain Trp_Tyr_perm PF03222.11 MSTRG.36975.1_3 - 0.031 13.2 0.0 0.034 13.1 0.0 1.0 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Alba PF01918.19 MSTRG.122284.1_2 - 0.00053 19.6 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 Alba DUF2648 PF10855.6 MSTRG.48402.1_3 - 0.1 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) GST_C_2 PF13410.4 MSTRG.77571.1_1 - 2e-08 33.9 0.0 4.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 MSTRG.77571.1_1 - 1.6e-06 28.2 0.0 3.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 MSTRG.77571.1_1 - 1.9e-05 24.8 0.0 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LURAP PF14854.4 MSTRG.32404.1_1 - 2.9e-05 23.9 0.4 4.1e-05 23.4 0.4 1.4 1 1 0 1 1 1 1 Leucine rich adaptor protein DUF2388 PF09498.8 MSTRG.32404.1_1 - 0.024 14.4 0.3 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) DUF4530 PF15039.4 MSTRG.32404.1_1 - 0.026 14.5 0.3 0.042 13.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Plasmod_MYXSPDY PF07981.9 MSTRG.116560.1_1 - 0.0062 16.5 11.5 1.5 8.9 0.5 3.3 3 0 0 3 3 3 3 Plasmodium repeat_MYXSPDY Plasmod_MYXSPDY PF07981.9 MSTRG.116560.1_2 - 1.2 9.2 12.8 1.5 8.9 0.5 2.8 3 0 0 3 3 3 0 Plasmodium repeat_MYXSPDY DUF1412 PF07203.9 MSTRG.116560.1_2 - 4.1 7.5 10.2 18 5.5 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1412) Plasmod_MYXSPDY PF07981.9 MSTRG.116560.1_3 - 0.0016 18.3 14.2 1.5 8.9 0.5 3.6 3 0 0 3 3 3 3 Plasmodium repeat_MYXSPDY WWE PF02825.18 MSTRG.39976.1_3 - 0.0013 19.1 1.9 0.002 18.5 1.9 1.4 1 0 0 1 1 1 1 WWE domain MatK_N PF01824.16 MSTRG.83771.1_2 - 0.03 13.8 0.1 0.031 13.8 0.1 1.0 1 0 0 1 1 1 0 MatK/TrnK amino terminal region CoaE PF01121.18 MSTRG.33661.1_3 - 9.6e-44 149.0 0.4 1.3e-43 148.6 0.4 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.4 MSTRG.33661.1_3 - 1.9e-08 34.5 0.1 5.4e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.4 MSTRG.33661.1_3 - 8.6e-05 22.7 1.7 0.00027 21.1 1.7 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.4 MSTRG.33661.1_3 - 0.00092 19.6 0.1 0.0019 18.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.10 MSTRG.33661.1_3 - 0.002 17.3 0.5 0.015 14.5 0.0 2.3 2 1 0 2 2 2 1 Zeta toxin PRK PF00485.16 MSTRG.33661.1_3 - 0.0041 16.7 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.18 MSTRG.33661.1_3 - 0.023 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.25 MSTRG.33661.1_3 - 0.044 14.1 0.5 0.077 13.4 0.5 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.4 MSTRG.33661.1_3 - 0.055 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ANTAR PF03861.12 MSTRG.33661.1_3 - 0.11 12.3 0.7 0.79 9.5 0.0 2.5 2 1 0 2 2 2 0 ANTAR domain KAP_NTPase PF07693.12 MSTRG.33661.1_3 - 0.13 11.4 0.1 0.15 11.1 0.1 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.4 MSTRG.33661.1_3 - 0.17 12.1 1.1 0.43 10.8 1.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.4 MSTRG.33661.1_3 - 0.19 11.9 0.6 1.5 9.0 0.4 2.5 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.4 MSTRG.32086.1_1 - 7.3e-08 32.3 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.4 MSTRG.32086.1_1 - 7.4e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.16 MSTRG.32086.1_1 - 0.00017 21.4 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein UvrD-helicase PF00580.19 MSTRG.32086.1_1 - 0.00055 19.4 0.3 0.0011 18.4 0.0 1.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.4 MSTRG.32086.1_1 - 0.00058 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.4 MSTRG.32086.1_1 - 0.00095 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.27 MSTRG.32086.1_1 - 0.0016 18.8 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.13 MSTRG.32086.1_1 - 0.0029 17.5 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.4 MSTRG.32086.1_1 - 0.0049 17.1 0.0 0.0069 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.15 MSTRG.32086.1_1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.14 MSTRG.32086.1_1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.4 MSTRG.32086.1_1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.20 MSTRG.32086.1_1 - 0.039 13.5 0.1 0.2 11.1 0.0 2.0 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain PIF1 PF05970.12 MSTRG.32086.1_1 - 0.061 12.3 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Helicase_RecD PF05127.12 MSTRG.32086.1_1 - 0.063 13.0 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Helicase Parvo_NS1 PF01057.15 MSTRG.32086.1_1 - 0.076 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Microtub_bd PF16796.3 MSTRG.32086.1_1 - 0.093 12.6 0.0 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 Microtubule binding Terminase_6 PF03237.13 MSTRG.32086.1_1 - 0.15 10.7 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family PI-PLC-Y PF00387.17 MSTRG.42790.1_1 - 8.3e-36 122.7 2.9 9.1e-36 122.6 0.1 2.4 2 1 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.28 MSTRG.42790.1_1 - 7.5e-14 51.7 0.0 1.8e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain DSPc PF00782.18 MSTRG.30786.1_2 - 4.3e-39 133.2 0.0 5.1e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 MSTRG.30786.1_2 - 9.8e-05 21.9 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.4 MSTRG.30786.1_2 - 0.017 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.12 MSTRG.30786.1_2 - 0.072 11.9 0.0 0.09 11.6 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Exostosin PF03016.13 MSTRG.29781.1_3 - 2.2e-30 105.8 0.1 3e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Exostosin family Anoct_dimer PF16178.3 MSTRG.45399.1_2 - 0.00048 19.8 2.2 0.073 12.6 0.4 2.0 1 1 1 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Glyco_transf_7N PF13733.4 MSTRG.45399.1_2 - 0.3 10.6 3.7 7 6.2 0.3 2.1 1 1 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 Tho2 PF11262.6 MSTRG.7691.1_1 - 0.01 14.9 5.3 0.015 14.4 5.3 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PTPlike_phytase PF14566.4 MSTRG.7691.1_1 - 0.014 15.4 4.2 0.019 15.0 4.2 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Reo_sigmaC PF04582.10 MSTRG.7691.1_1 - 0.018 14.3 3.8 0.31 10.3 1.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.10 MSTRG.7691.1_1 - 0.19 11.6 8.9 0.039 13.8 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.10 MSTRG.7691.1_1 - 0.26 11.2 15.2 0.14 12.1 5.8 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FUSC PF04632.10 MSTRG.7691.1_1 - 0.28 9.6 0.8 0.32 9.4 0.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PRKG1_interact PF15898.3 MSTRG.7691.1_1 - 0.34 11.7 12.0 0.87 10.4 12.0 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4829 PF16111.3 MSTRG.7691.1_1 - 0.49 11.1 4.4 0.55 10.9 3.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4829) DUF2968 PF11180.6 MSTRG.7691.1_1 - 0.5 9.9 10.0 0.081 12.5 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) TMCO5 PF14992.4 MSTRG.7691.1_1 - 0.58 9.6 17.3 0.55 9.6 14.8 1.8 1 1 1 2 2 2 0 TMCO5 family Atg14 PF10186.7 MSTRG.7691.1_1 - 1 8.3 10.9 3.1 6.7 10.4 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Agouti PF05039.10 MSTRG.7691.1_1 - 1.2 9.8 6.9 0.47 11.1 3.9 1.8 1 1 1 2 2 2 0 Agouti protein APG6 PF04111.10 MSTRG.7691.1_1 - 1.5 8.0 15.6 1.5 8.0 13.8 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Fzo_mitofusin PF04799.11 MSTRG.7691.1_1 - 2.1 7.7 9.7 0.36 10.2 4.1 1.9 1 1 1 2 2 2 0 fzo-like conserved region DUF641 PF04859.10 MSTRG.7691.1_1 - 2.7 8.2 11.9 1.9 8.7 4.1 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HIP1_clath_bdg PF16515.3 MSTRG.7691.1_1 - 3.7 8.1 18.8 8.9 6.9 7.6 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.10 MSTRG.7691.1_1 - 4.9 7.7 12.4 3.3 8.3 4.5 2.8 1 1 1 2 2 2 0 SlyX TMF_DNA_bd PF12329.6 MSTRG.7691.1_1 - 5.7 6.9 18.0 13 5.7 1.4 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.10 MSTRG.7691.1_1 - 6.4 7.2 15.5 8.1e+02 0.4 15.5 3.0 1 1 0 1 1 1 0 Cell division protein ZapB Cornifin PF02389.13 MSTRG.98005.1_1 - 1.1e-06 28.7 0.6 1.2e-06 28.6 0.6 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family HTH_22 PF13309.4 MSTRG.135499.1_2 - 0.11 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 HTH domain Arm PF00514.21 MSTRG.19266.1_2 - 1.6e-19 69.1 1.9 2.9e-07 30.2 0.0 5.0 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.7 MSTRG.19266.1_2 - 0.017 15.0 0.3 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.4 MSTRG.19266.1_2 - 0.02 15.2 0.2 0.29 11.5 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.4 MSTRG.19266.1_2 - 0.089 13.1 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 HEAT repeats YbgT_YccB PF08173.9 MSTRG.131448.1_1 - 0.064 13.3 1.0 0.1 12.6 1.0 1.3 1 0 0 1 1 1 0 Membrane bound YbgT-like protein DUF3679 PF12438.6 MSTRG.131448.1_1 - 1.2 8.8 3.8 2 8.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3679) Arm PF00514.21 MSTRG.137809.1_3 - 4.8e-06 26.3 4.3 0.017 15.0 0.0 3.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat NopRA1 PF16201.3 MSTRG.137809.1_3 - 0.17 11.3 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Antimicrobial14 PF08109.9 MSTRG.52387.1_1 - 0.055 13.4 0.7 0.53 10.2 0.1 2.1 2 0 0 2 2 2 0 Lactocin 705 family Antimicrobial14 PF08109.9 MSTRG.52387.1_2 - 0.0014 18.5 0.7 0.53 10.2 0.1 2.2 2 0 0 2 2 2 2 Lactocin 705 family zf-RAG1 PF10426.7 MSTRG.82697.1_3 - 0.023 14.7 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain TPR_12 PF13424.4 MSTRG.117100.1_2 - 3.5e-64 212.9 20.7 1.2e-20 73.5 2.2 4.2 2 1 3 5 5 4 4 Tetratricopeptide repeat TPR_10 PF13374.4 MSTRG.117100.1_2 - 1.3e-57 190.1 8.4 8.8e-16 57.1 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.4 MSTRG.117100.1_2 - 6.5e-27 91.4 13.1 5.1e-06 26.0 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.26 MSTRG.117100.1_2 - 5.3e-25 86.0 27.1 1.5e-07 30.8 0.5 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.15 MSTRG.117100.1_2 - 1.7e-18 65.0 23.7 0.00038 20.2 2.7 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.4 MSTRG.117100.1_2 - 2.9e-13 48.8 22.6 0.0016 18.4 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.4 MSTRG.117100.1_2 - 1.2e-12 48.1 6.9 3e-05 24.3 0.2 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.4 MSTRG.117100.1_2 - 1.2e-12 48.1 2.2 0.0021 18.6 2.2 4.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.4 MSTRG.117100.1_2 - 4.7e-10 39.3 4.7 0.77 10.6 0.4 5.7 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.4 MSTRG.117100.1_2 - 1.3e-08 34.5 7.3 0.027 14.7 0.2 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.5 MSTRG.117100.1_2 - 1.3e-07 31.6 9.3 0.0054 16.8 0.6 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.12 MSTRG.117100.1_2 - 8.3e-05 22.7 0.0 23 5.8 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.18 MSTRG.117100.1_2 - 0.00019 21.3 0.8 0.14 12.3 0.0 3.9 5 0 0 5 5 2 1 PPR repeat Uso1_p115_C PF04871.11 MSTRG.117100.1_2 - 0.0014 18.9 10.7 0.0014 18.9 10.7 2.0 2 0 0 2 2 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region COG2 PF06148.9 MSTRG.117100.1_2 - 0.0085 16.0 4.3 0.021 14.8 4.3 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2225 PF09986.7 MSTRG.117100.1_2 - 0.01 15.4 1.9 0.84 9.2 0.5 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TMF_TATA_bd PF12325.6 MSTRG.117100.1_2 - 0.016 15.3 8.9 0.016 15.3 8.9 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding PPR_2 PF13041.4 MSTRG.117100.1_2 - 0.031 14.3 1.2 2.5 8.3 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family DUF4919 PF16266.3 MSTRG.117100.1_2 - 0.035 13.9 0.4 0.23 11.3 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4919) RPN7 PF10602.7 MSTRG.117100.1_2 - 0.04 13.4 2.0 3.8 7.0 0.1 3.3 1 1 1 3 3 3 0 26S proteasome subunit RPN7 JIP_LZII PF16471.3 MSTRG.117100.1_2 - 0.053 13.6 10.3 0.026 14.6 4.2 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF627 PF04781.10 MSTRG.117100.1_2 - 0.065 13.1 2.7 2.9 7.8 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF627) WbqC PF08889.9 MSTRG.117100.1_2 - 0.072 12.9 1.6 11 5.7 0.0 3.3 3 1 1 4 4 4 0 WbqC-like protein family MIT PF04212.16 MSTRG.117100.1_2 - 0.17 11.8 11.8 18 5.4 2.8 5.0 4 1 1 5 5 4 0 MIT (microtubule interacting and transport) domain Clathrin PF00637.18 MSTRG.117100.1_2 - 0.25 11.1 4.2 0.72 9.6 0.7 3.2 1 1 1 2 2 2 0 Region in Clathrin and VPS SHNi-TPR PF10516.7 MSTRG.117100.1_2 - 0.27 10.6 4.8 12 5.3 0.1 4.5 5 0 0 5 5 5 0 SHNi-TPR TPR_11 PF13414.4 MSTRG.117100.1_2 - 0.42 10.2 16.3 0.078 12.5 0.8 5.1 5 0 0 5 5 5 0 TPR repeat TPR_6 PF13174.4 MSTRG.117100.1_2 - 2.2 9.0 13.2 1.4 9.5 0.2 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF972 PF06156.11 MSTRG.117100.1_2 - 2.5 8.7 15.2 1.6 9.3 7.0 3.9 2 1 0 3 3 3 0 Protein of unknown function (DUF972) DUF342 PF03961.11 MSTRG.117100.1_2 - 5.1 5.4 7.3 8.5 4.7 6.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TPR_3 PF07720.10 MSTRG.117100.1_2 - 5.2 7.0 12.9 3.9 7.4 1.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MIP PF00230.18 MSTRG.47217.1_1 - 0.17 11.4 6.4 0.22 11.1 6.4 1.1 1 0 0 1 1 1 0 Major intrinsic protein zf-C4 PF00105.16 MSTRG.110476.2_2 - 1.3e-32 112.0 16.8 2.1e-32 111.3 16.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 MSTRG.110476.2_2 - 1.4e-22 80.2 0.0 2.7e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TT_ORF2 PF02957.13 MSTRG.110476.2_2 - 0.15 12.8 9.1 0.4 11.5 9.1 1.6 1 0 0 1 1 1 0 TT viral ORF2 Patatin PF01734.20 MSTRG.58370.1_2 - 0.1 12.6 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Patatin-like phospholipase Piwi PF02171.15 MSTRG.141588.1_1 - 1.5e-31 109.6 0.0 1.8e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Piwi domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.108619.1_1 - 1.1e-15 57.5 1.2 1.3e-15 57.3 1.2 1.0 1 0 0 1 1 1 1 Transposase Arg_repressor PF01316.19 MSTRG.108619.1_1 - 0.00032 20.3 0.0 0.00037 20.1 0.0 1.1 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain RVT_1 PF00078.25 MSTRG.20582.1_2 - 8.4e-08 31.9 0.1 9.6e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1_7 PF13843.4 MSTRG.18362.1_2 - 5.6e-17 61.9 0.0 7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 FKBP_C PF00254.26 MSTRG.56215.1_3 - 1.3e-36 124.6 0.0 8e-20 70.8 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.30 MSTRG.56215.1_3 - 1.5e-06 27.2 0.9 0.0077 15.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.4 MSTRG.56215.1_3 - 2.8e-05 23.3 0.7 0.12 11.8 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 MSTRG.56215.1_3 - 4.5e-05 23.7 0.0 0.00016 22.0 0.0 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.4 MSTRG.56215.1_3 - 8.1e-05 22.1 0.1 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.4 MSTRG.56215.1_3 - 0.05 13.2 0.2 4.6 7.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair CP2 PF04516.13 MSTRG.101593.2_2 - 4.8e-38 130.6 0.0 6.1e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor ABC_transp_aux PF09822.7 MSTRG.84043.1_1 - 6.1e-09 35.6 0.0 6.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDE_3 PF13358.4 MSTRG.91019.1_3 - 3.9e-07 29.8 1.9 5.9e-07 29.2 1.9 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Yae1_N PF09811.7 MSTRG.47464.1_2 - 0.057 13.0 35.0 0.13 11.9 0.4 5.2 5 1 0 5 5 5 0 Essential protein Yae1, N terminal KRTAP PF11759.6 MSTRG.47464.1_2 - 0.13 12.7 149.9 1.2 9.6 49.5 4.9 1 1 2 3 3 3 0 Keratin-associated matrix MspA PF09203.9 MSTRG.47464.1_3 - 0.00075 19.2 15.3 42 3.8 15.3 3.0 1 1 0 1 1 1 0 MspA Keratin_2_head PF16208.3 MSTRG.47464.1_3 - 0.05 13.6 9.2 25 4.9 9.2 2.8 1 1 0 1 1 1 0 Keratin type II head Yae1_N PF09811.7 MSTRG.47464.1_3 - 0.2 11.3 20.4 1.8e+02 1.8 0.0 7.6 3 2 0 3 3 3 0 Essential protein Yae1, N terminal DUF2715 PF10895.6 MSTRG.47464.1_3 - 0.48 10.0 17.3 1.6e+04 -6.5 17.3 4.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2715) KRTAP PF11759.6 MSTRG.47464.1_3 - 0.49 10.9 5.8 35 4.9 5.8 2.9 1 1 0 1 1 1 0 Keratin-associated matrix OMP_b-brl_2 PF13568.4 MSTRG.47464.1_3 - 2.4 8.1 5.9 85 3.0 2.4 3.8 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain BAH PF01426.16 MSTRG.22075.1_3 - 1.5e-06 27.9 0.0 5.3e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 BAH domain ERAP1_C PF11838.6 MSTRG.62159.1_3 - 1.5e-59 202.0 2.8 1.9e-59 201.7 2.8 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Fungus-induced PF10917.6 MSTRG.26492.1_2 - 0.076 13.2 0.5 0.12 12.5 0.2 1.5 2 0 0 2 2 2 0 Fungus-induced protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.131864.1_1 - 9.5e-06 25.6 0.4 1.3e-05 25.2 0.4 1.2 1 0 0 1 1 1 1 Transposase Notch PF00066.15 MSTRG.118369.1_2 - 0.0075 16.6 0.1 0.011 16.0 0.1 1.3 1 0 0 1 1 1 1 LNR domain GDA1_CD39 PF01150.15 MSTRG.133742.1_3 - 2.7e-48 164.5 0.0 3e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family EF-hand_6 PF13405.4 MSTRG.128348.3_1 - 1.1e-06 28.0 0.2 2.6e-06 26.8 0.2 1.7 1 1 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.30 MSTRG.128348.3_1 - 2.6e-06 26.4 1.6 3.6e-06 26.0 0.2 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.4 MSTRG.128348.3_1 - 2.8e-06 26.9 2.7 0.0007 19.2 0.4 2.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.4 MSTRG.128348.3_1 - 0.00026 20.2 0.6 0.00026 20.2 0.6 1.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.4 MSTRG.128348.3_1 - 0.00027 21.2 0.0 0.00038 20.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair Uso1_p115_C PF04871.11 MSTRG.128348.3_1 - 0.0068 16.6 0.1 0.0091 16.2 0.1 1.2 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region DDE_3 PF13358.4 MSTRG.38611.1_1 - 2.7e-11 43.3 0.3 3.1e-11 43.1 0.3 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.24 MSTRG.38611.1_1 - 0.0018 18.4 0.0 0.0018 18.4 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain Flp_N PF03930.12 MSTRG.104671.1_1 - 0.0066 16.3 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 Recombinase Flp protein N-terminus DUF837 PF05769.9 MSTRG.104671.1_1 - 0.019 14.8 3.5 0.025 14.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF837) APC_N_CC PF16689.3 MSTRG.104671.1_1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Ax_dynein_light PF10211.7 MSTRG.104671.1_1 - 0.061 13.1 2.4 0.076 12.8 2.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain RolB_RolC PF02027.15 MSTRG.104671.1_1 - 0.069 12.7 0.4 0.072 12.6 0.4 1.1 1 0 0 1 1 1 0 RolB/RolC glucosidase family Lipoprotein_20 PF13942.4 MSTRG.104671.1_1 - 0.1 12.4 3.7 0.1 12.4 3.0 1.3 1 1 0 1 1 1 0 YfhG lipoprotein APG6 PF04111.10 MSTRG.104671.1_1 - 0.46 9.7 5.5 0.5 9.6 5.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.13 MSTRG.104671.1_1 - 0.77 9.4 5.6 0.37 10.5 0.2 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF1465 PF07323.10 MSTRG.77973.1_1 - 1.2 8.8 5.5 1.4 8.7 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) CCDC23 PF15674.3 MSTRG.72516.1_1 - 0.18 11.7 0.0 1.1 9.1 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 CSD PF00313.20 MSTRG.34987.3_2 - 3.7e-25 87.4 0.6 6.3e-25 86.7 0.6 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.9 MSTRG.34987.3_2 - 0.025 14.1 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain ACT_3 PF10000.7 MSTRG.127879.1_2 - 0.082 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 ACT domain Mu-like_Com PF10122.7 MSTRG.39818.1_3 - 0.024 14.0 0.4 4.3 6.7 0.2 2.3 2 1 0 2 2 2 0 Mu-like prophage protein Com Nup188 PF10487.7 MSTRG.28867.1_2 - 2.8e-09 35.4 0.4 3.2e-09 35.2 0.4 1.0 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Pox_T4_N PF04491.10 MSTRG.28867.1_2 - 0.016 15.0 0.6 0.029 14.1 0.6 1.5 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus RabGAP-TBC PF00566.16 MSTRG.28867.1_2 - 0.025 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Myotub-related PF06602.12 MSTRG.81073.1_2 - 8.5e-102 340.5 0.0 1e-101 340.2 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.25 MSTRG.81073.1_2 - 4.2e-05 23.1 0.0 6.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.18 MSTRG.81073.1_2 - 0.0022 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.4 MSTRG.81073.1_2 - 0.0098 15.7 0.1 0.014 15.2 0.1 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family SF3b1 PF08920.8 MSTRG.22853.2_1 - 8.5e-50 168.1 42.8 6e-48 162.1 7.1 4.9 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 Menin PF05053.11 MSTRG.22853.2_1 - 0.22 9.7 2.7 0.37 9.0 2.7 1.3 1 0 0 1 1 1 0 Menin MIF4G_like_2 PF09090.9 MSTRG.19194.1_1 - 3.2e-27 95.5 6.7 3.5e-27 95.4 6.7 1.0 1 0 0 1 1 1 1 MIF4G like Vfa1 PF08432.8 MSTRG.19194.1_1 - 0.00083 19.6 8.5 0.00096 19.4 8.5 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Mnd1 PF03962.13 MSTRG.19194.1_1 - 0.0039 16.9 9.8 0.0048 16.7 9.8 1.1 1 0 0 1 1 1 1 Mnd1 family AAA_13 PF13166.4 MSTRG.19194.1_1 - 0.0044 15.6 8.6 0.0052 15.4 8.6 1.0 1 0 0 1 1 1 1 AAA domain GBP_C PF02841.12 MSTRG.19194.1_1 - 0.0044 16.3 9.2 0.0049 16.2 9.2 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain DUF1664 PF07889.10 MSTRG.19194.1_1 - 0.0048 16.7 5.2 0.0064 16.3 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF1510 PF07423.9 MSTRG.19194.1_1 - 0.0054 16.1 5.9 0.0054 16.1 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ufd2P_core PF10408.7 MSTRG.19194.1_1 - 0.0054 15.2 2.2 0.0065 15.0 2.2 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core tRNA_bind_2 PF13725.4 MSTRG.19194.1_1 - 0.0092 15.6 9.2 0.012 15.3 9.2 1.1 1 0 0 1 1 1 1 Possible tRNA binding domain RRN3 PF05327.9 MSTRG.19194.1_1 - 0.011 14.2 6.1 0.012 14.0 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2203 PF09969.7 MSTRG.19194.1_1 - 0.012 16.2 4.5 0.014 15.9 4.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HemX PF04375.12 MSTRG.19194.1_1 - 0.017 14.3 8.2 0.02 14.1 8.2 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CorA PF01544.16 MSTRG.19194.1_1 - 0.02 14.1 6.2 0.069 12.3 0.5 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF1690 PF07956.9 MSTRG.19194.1_1 - 0.024 14.9 9.4 0.034 14.4 9.4 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Jnk-SapK_ap_N PF09744.7 MSTRG.19194.1_1 - 0.027 14.6 13.7 0.033 14.3 13.7 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 LUC7 PF03194.13 MSTRG.19194.1_1 - 0.029 13.9 8.9 0.034 13.6 8.9 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Spore_YhcN_YlaJ PF09580.8 MSTRG.19194.1_1 - 0.03 14.3 3.4 0.04 13.8 3.4 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Afi1 PF07792.10 MSTRG.19194.1_1 - 0.03 14.7 6.0 0.036 14.4 6.0 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Fib_alpha PF08702.8 MSTRG.19194.1_1 - 0.032 14.3 8.2 0.038 14.0 8.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.10 MSTRG.19194.1_1 - 0.034 14.0 6.4 0.043 13.7 6.4 1.1 1 0 0 1 1 1 0 Laminin Domain II Atg14 PF10186.7 MSTRG.19194.1_1 - 0.036 13.0 7.5 0.047 12.6 7.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.3 MSTRG.19194.1_1 - 0.036 14.8 10.7 0.054 14.3 10.7 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF342 PF03961.11 MSTRG.19194.1_1 - 0.038 12.4 8.6 0.043 12.3 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prefoldin_2 PF01920.18 MSTRG.19194.1_1 - 0.04 13.8 14.9 0.29 11.0 2.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit DASH_Dad4 PF08650.8 MSTRG.19194.1_1 - 0.048 13.5 1.8 1.8 8.4 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad4 PCRF PF03462.16 MSTRG.19194.1_1 - 0.052 13.3 6.7 0.06 13.1 6.7 1.1 1 0 0 1 1 1 0 PCRF domain LPP PF04728.11 MSTRG.19194.1_1 - 0.055 13.7 4.7 3.9 7.8 0.3 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Cob_adeno_trans PF01923.16 MSTRG.19194.1_1 - 0.056 13.4 2.2 0.066 13.2 2.2 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase 5_nucleotid PF05761.12 MSTRG.19194.1_1 - 0.067 11.9 5.7 0.075 11.8 5.7 1.0 1 0 0 1 1 1 0 5' nucleotidase family DUF106 PF01956.14 MSTRG.19194.1_1 - 0.082 12.5 5.9 0.11 12.1 5.9 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 V_ATPase_I PF01496.17 MSTRG.19194.1_1 - 0.085 10.6 7.5 0.098 10.4 7.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOGA PF11365.6 MSTRG.19194.1_1 - 0.086 13.9 11.9 0.11 13.5 11.9 1.1 1 0 0 1 1 1 0 Protein SOGA TMPIT PF07851.11 MSTRG.19194.1_1 - 0.096 11.8 6.3 0.12 11.5 6.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Folliculin PF11704.6 MSTRG.19194.1_1 - 0.11 12.2 5.3 0.15 11.8 5.3 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport RmuC PF02646.14 MSTRG.19194.1_1 - 0.13 11.3 12.2 0.44 9.5 1.3 2.0 1 1 1 2 2 2 0 RmuC family FliJ PF02050.14 MSTRG.19194.1_1 - 0.13 12.3 15.7 0.13 12.3 6.7 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein OmpH PF03938.12 MSTRG.19194.1_1 - 0.14 12.0 15.5 0.19 11.6 15.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DASH_Spc34 PF08657.8 MSTRG.19194.1_1 - 0.15 11.7 13.4 0.18 11.5 13.4 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 HisKA_3 PF07730.11 MSTRG.19194.1_1 - 0.16 12.4 2.5 1.9 8.9 0.2 2.1 2 0 0 2 2 2 0 Histidine kinase Uds1 PF15456.4 MSTRG.19194.1_1 - 0.16 12.0 9.2 0.22 11.6 9.2 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Serinc PF03348.13 MSTRG.19194.1_1 - 0.22 10.3 1.5 0.23 10.2 1.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLZ PF16526.3 MSTRG.19194.1_1 - 0.22 11.8 12.5 1.7 8.9 1.1 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-H PF05837.10 MSTRG.19194.1_1 - 0.28 11.5 9.6 0.34 11.2 9.6 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.3 MSTRG.19194.1_1 - 0.29 11.1 12.9 0.84 9.6 3.0 2.1 1 1 0 2 2 2 0 TolA binding protein trimerisation FAM60A PF15396.4 MSTRG.19194.1_1 - 0.3 10.9 4.6 0.34 10.8 4.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A AAA_11 PF13086.4 MSTRG.19194.1_1 - 0.31 10.6 7.1 0.34 10.5 7.1 1.0 1 0 0 1 1 1 0 AAA domain DUF4746 PF15928.3 MSTRG.19194.1_1 - 0.32 10.3 7.9 0.36 10.1 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CCDC-167 PF15188.4 MSTRG.19194.1_1 - 0.38 11.0 10.6 0.52 10.5 10.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 FemAB PF02388.14 MSTRG.19194.1_1 - 0.39 9.4 8.8 0.51 9.0 8.8 1.1 1 0 0 1 1 1 0 FemAB family TBPIP PF07106.11 MSTRG.19194.1_1 - 0.54 9.9 16.5 0.71 9.5 4.3 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.12 MSTRG.19194.1_1 - 0.61 9.7 13.6 0.8 9.3 13.6 1.1 1 0 0 1 1 1 0 IncA protein DUF3381 PF11861.6 MSTRG.19194.1_1 - 0.64 9.7 18.2 0.95 9.2 18.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Peptidase_S49_N PF08496.8 MSTRG.19194.1_1 - 0.66 9.9 7.7 0.95 9.4 7.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Swi5 PF07061.9 MSTRG.19194.1_1 - 0.67 9.9 14.1 1.7e+02 2.2 14.1 2.1 1 1 0 1 1 1 0 Swi5 DPM3 PF08285.9 MSTRG.19194.1_1 - 0.72 9.9 3.3 0.87 9.7 0.1 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) APG6 PF04111.10 MSTRG.19194.1_1 - 0.72 9.1 12.4 0.9 8.7 12.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PHM7_cyt PF14703.4 MSTRG.19194.1_1 - 1 9.5 11.1 1.8 8.6 11.1 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter SlyX PF04102.10 MSTRG.19194.1_1 - 1.1 9.8 12.4 2.5 8.7 4.1 2.1 1 1 1 2 2 2 0 SlyX CLN3 PF02487.15 MSTRG.19194.1_1 - 1.2 7.9 3.3 1.3 7.8 3.3 1.0 1 0 0 1 1 1 0 CLN3 protein FAM176 PF14851.4 MSTRG.19194.1_1 - 1.3 8.6 6.9 1.6 8.3 6.9 1.2 1 0 0 1 1 1 0 FAM176 family DUF4820 PF16091.3 MSTRG.19194.1_1 - 1.3 8.2 8.3 1.6 7.9 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SNARE PF05739.17 MSTRG.19194.1_1 - 1.4 8.8 4.0 19 5.2 0.1 2.3 2 0 0 2 2 2 0 SNARE domain 60KD_IMP PF02096.18 MSTRG.19194.1_1 - 1.7 8.4 10.5 0.86 9.4 3.4 2.1 1 1 1 2 2 2 0 60Kd inner membrane protein Alanine_zipper PF11839.6 MSTRG.19194.1_1 - 1.7 8.8 8.7 3.6 7.8 1.5 2.1 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Presenilin PF01080.15 MSTRG.19194.1_1 - 2 7.0 6.3 2.2 6.8 6.3 1.0 1 0 0 1 1 1 0 Presenilin DUF948 PF06103.9 MSTRG.19194.1_1 - 2.1 8.5 4.3 11 6.3 4.4 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF5082 PF16888.3 MSTRG.19194.1_1 - 2.9 8.1 16.5 6.3 7.0 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) T3SS_needle_E PF08988.8 MSTRG.19194.1_1 - 3.1 7.9 7.8 0.61 10.2 1.7 2.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle HSP70 PF00012.18 MSTRG.19194.1_1 - 3.1 5.7 10.4 3.7 5.5 10.4 1.0 1 0 0 1 1 1 0 Hsp70 protein CK_II_beta PF01214.16 MSTRG.19194.1_1 - 3.1 7.5 6.8 9.4 5.9 6.8 1.7 1 1 0 1 1 1 0 Casein kinase II regulatory subunit DUF5093 PF17011.3 MSTRG.19194.1_1 - 3.5 7.8 10.6 0.79 9.9 6.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5093) CREPT PF16566.3 MSTRG.19194.1_1 - 3.5 7.6 12.1 0.86 9.6 3.7 2.0 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour MtrG PF04210.11 MSTRG.19194.1_1 - 3.7 7.3 5.8 5.1 6.9 0.6 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3847 PF12958.5 MSTRG.19194.1_1 - 4.4 7.4 18.5 0.83 9.7 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) FlaC_arch PF05377.9 MSTRG.19194.1_1 - 5 7.4 10.4 12 6.2 2.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.11 MSTRG.19194.1_1 - 5.2 6.4 10.1 2.1 7.7 1.4 2.0 1 1 1 2 2 2 0 fzo-like conserved region Dzip-like_N PF13815.4 MSTRG.19194.1_1 - 5.7 6.8 14.2 0.27 11.1 4.2 2.1 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DASH_Spc19 PF08287.9 MSTRG.19194.1_1 - 6.6 6.5 15.9 12 5.6 15.9 1.4 1 1 0 1 1 1 0 Spc19 FlxA PF14282.4 MSTRG.19194.1_1 - 7.3 6.5 21.5 1e+02 2.9 21.5 2.1 1 1 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.4 MSTRG.19194.1_1 - 8.6 6.7 13.8 12 6.3 2.5 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Allatostatin PF05953.10 MSTRG.42624.1_3 - 0.12 12.9 0.4 2e+02 3.1 0.0 3.2 3 0 0 3 3 3 0 Allatostatin MGTL PF17059.3 MSTRG.42624.1_3 - 0.53 10.0 5.7 42 4.0 0.0 3.6 4 0 0 4 4 4 0 MgtA leader peptide Serpin PF00079.18 MSTRG.22107.1_2 - 1.3e-108 363.5 0.0 1.5e-108 363.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RVT_1 PF00078.25 MSTRG.40703.1_3 - 0.0028 17.1 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.4 MSTRG.136176.1_1 - 1.4e-06 28.0 0.1 1.7e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1514 PF07438.9 MSTRG.14430.1_1 - 0.025 14.7 0.3 0.046 13.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) PRY PF13765.4 MSTRG.15290.2_3 - 6e-21 73.7 0.2 1e-20 72.9 0.2 1.4 1 0 0 1 1 1 1 SPRY-associated domain LRR_6 PF13516.4 MSTRG.15290.2_3 - 3.6e-15 54.5 4.3 6.2e-06 25.7 0.3 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.31 MSTRG.15290.2_3 - 1e-05 25.1 2.3 0.51 10.9 0.3 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.5 MSTRG.15290.2_3 - 1.3e-05 25.3 3.5 0.0036 17.5 1.6 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 MSTRG.15290.2_3 - 0.026 14.1 3.0 0.97 9.1 0.4 3.1 3 0 0 3 3 3 0 Leucine rich repeat SPRY PF00622.26 MSTRG.15290.2_3 - 0.044 13.8 0.3 0.075 13.0 0.3 1.4 1 0 0 1 1 1 0 SPRY domain Collagen PF01391.16 MSTRG.42115.1_2 - 1.3e-08 34.3 16.1 1.6e-08 34.0 16.1 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Tubulin_C PF03953.15 MSTRG.63610.1_2 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain UBA PF00627.29 MSTRG.64085.1_3 - 5e-05 23.0 0.0 8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_2 PF08587.9 MSTRG.64085.1_3 - 0.036 14.1 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) SSF PF00474.15 MSTRG.22223.1_3 - 4.8e-49 167.2 11.5 7.4e-49 166.6 11.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family PTPLA PF04387.12 MSTRG.121691.1_2 - 1.1e-45 155.2 10.1 1.2e-45 155.1 10.1 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF320 PF03777.11 MSTRG.142127.1_1 - 0.027 14.2 1.3 8.2 6.2 0.1 3.5 1 1 2 3 3 3 0 Small secreted domain (DUF320) DUF1731 PF08338.9 MSTRG.142127.1_2 - 0.0049 16.5 1.0 49 3.7 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1731) Tudor-knot PF11717.6 MSTRG.142127.1_2 - 0.055 13.2 7.4 19 5.1 0.1 3.8 1 1 3 4 4 4 0 RNA binding activity-knot of a chromodomain DUF4248 PF14053.4 MSTRG.142127.1_2 - 0.069 13.1 1.5 7.8 6.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4248) Sec2p PF06428.9 MSTRG.95223.1_2 - 0.01 15.6 1.0 2 8.3 0.1 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4094 PF13334.4 MSTRG.95223.1_2 - 0.044 14.0 0.6 0.099 12.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) TRADD_N PF09034.8 MSTRG.95223.1_2 - 0.075 12.9 2.0 0.12 12.3 0.6 1.8 1 1 1 2 2 2 0 TRADD, N-terminal domain Proteasome PF00227.24 MSTRG.51862.1_2 - 3.3e-66 222.3 0.3 4.3e-66 221.9 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 MSTRG.51862.1_2 - 2e-14 52.8 0.5 4.6e-14 51.6 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF4606 PF15379.4 MSTRG.108574.1_2 - 1.6e-10 41.0 2.3 2.9e-10 40.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4606) HHH_8 PF14716.4 MSTRG.23475.1_1 - 1.3e-19 70.2 1.3 3.4e-18 65.7 0.7 2.5 2 1 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.7 MSTRG.23475.1_1 - 1.7e-19 69.3 0.1 1.5e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.4 MSTRG.23475.1_1 - 1.9e-07 31.5 0.1 0.00015 22.2 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_2 PF12826.5 MSTRG.23475.1_1 - 0.0014 18.5 0.0 0.13 12.3 0.0 2.6 1 1 1 2 2 2 1 Helix-hairpin-helix motif Cactin_mid PF10312.7 MSTRG.23475.1_1 - 0.0015 18.2 0.7 0.33 10.5 0.2 2.2 2 0 0 2 2 2 2 Conserved mid region of cactin HHH PF00633.21 MSTRG.23475.1_1 - 0.0061 16.2 0.7 9.8 6.1 0.2 3.3 3 0 0 3 3 3 2 Helix-hairpin-helix motif Cdd1 PF11731.6 MSTRG.23475.1_1 - 0.0077 16.3 0.0 0.16 12.1 0.0 2.4 1 1 1 2 2 2 1 Pathogenicity locus HHH_3 PF12836.5 MSTRG.23475.1_1 - 0.075 13.2 0.2 14 5.9 0.0 3.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif DUF4806 PF16064.3 MSTRG.23475.1_1 - 0.094 12.9 0.6 0.49 10.6 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4806) FGE-sulfatase PF03781.14 MSTRG.132790.1_1 - 6.2e-27 94.7 0.3 9.5e-27 94.1 0.3 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 HTH_Tnp_Tc3_2 PF01498.16 MSTRG.21651.1_2 - 0.0019 18.2 3.0 0.0048 17.0 3.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.4 MSTRG.21651.1_3 - 2e-12 47.0 0.0 3.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.16 MSTRG.21651.1_3 - 0.0025 17.9 1.5 0.0097 16.0 0.2 2.3 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.4 MSTRG.21651.1_3 - 0.011 16.2 0.1 0.041 14.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain PAX PF00292.16 MSTRG.21651.1_3 - 0.022 14.5 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 'Paired box' domain IBN_N PF03810.17 MSTRG.42198.1_2 - 6.5e-06 25.8 0.1 7.8e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain ComC PF03047.12 MSTRG.70714.1_3 - 0.087 12.6 0.2 0.21 11.4 0.2 1.7 1 0 0 1 1 1 0 COMC family I-set PF07679.14 MSTRG.47273.1_1 - 4.8e-63 209.1 0.0 6.6e-16 58.0 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.47273.1_1 - 1.9e-41 140.4 0.0 2.9e-13 50.1 0.0 5.9 6 0 0 6 6 6 4 Immunoglobulin domain fn3 PF00041.19 MSTRG.47273.1_1 - 2.6e-40 136.5 0.2 6.1e-12 45.6 0.0 3.5 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.4 MSTRG.47273.1_1 - 4.8e-18 65.1 0.0 1.9e-07 31.2 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.23 MSTRG.47273.1_1 - 2.8e-17 62.5 0.0 6.9e-06 26.0 0.0 5.6 6 0 0 6 6 6 4 Immunoglobulin domain V-set PF07686.15 MSTRG.47273.1_1 - 9.6e-10 38.5 0.2 0.57 10.2 0.1 6.6 5 2 0 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.10 MSTRG.47273.1_1 - 0.00018 21.3 0.0 4.1 7.4 0.0 3.7 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain LURAP PF14854.4 MSTRG.31737.1_3 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Leucine rich adaptor protein Dapper PF15268.4 MSTRG.31737.1_3 - 0.012 14.4 0.6 0.015 14.0 0.6 1.1 1 0 0 1 1 1 0 Dapper Mito_carr PF00153.25 MSTRG.122445.1_3 - 1.3e-17 63.4 0.0 6e-11 42.0 0.0 3.2 3 0 0 3 3 3 2 Mitochondrial carrier protein Birna_VP2 PF01766.15 MSTRG.122445.1_3 - 0.029 13.2 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP2 protein RVT_1 PF00078.25 MSTRG.27795.1_2 - 0.031 13.6 0.0 0.038 13.4 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TANGO2 PF05742.10 MSTRG.119711.1_2 - 9.8e-26 91.2 0.0 1.2e-25 90.9 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Fe_dep_repress PF01325.17 MSTRG.27274.1_1 - 0.059 13.4 0.9 12 6.1 0.0 3.2 1 1 1 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain B2 PF11473.6 MSTRG.27274.1_1 - 0.49 10.1 4.5 2e+02 1.8 0.0 4.6 1 1 5 6 6 6 0 RNA binding protein B2 TfoX_C PF04994.11 MSTRG.27274.1_3 - 0.0042 17.0 0.1 4.8 7.2 0.0 2.5 1 1 2 3 3 3 3 TfoX C-terminal domain DUF4332 PF14229.4 MSTRG.27274.1_3 - 0.14 12.2 0.6 58 3.8 0.1 2.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4332) DUF4366 PF14283.4 MSTRG.142751.1_3 - 0.00031 20.2 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) EGF_2 PF07974.11 MSTRG.142751.1_3 - 0.00054 20.1 70.7 0.027 14.7 10.3 5.8 5 0 0 5 5 5 4 EGF-like domain hEGF PF12661.5 MSTRG.142751.1_3 - 0.0017 18.8 40.8 0.089 13.4 1.6 6.8 5 1 0 5 5 5 3 Human growth factor-like EGF EGF PF00008.25 MSTRG.142751.1_3 - 0.0024 18.0 58.0 0.07 13.3 5.2 6.0 4 1 1 5 5 5 4 EGF-like domain DUF3377 PF11857.6 MSTRG.142751.1_3 - 0.038 13.8 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DER1 PF04511.13 MSTRG.76282.2_2 - 1.5e-38 132.3 10.0 1.7e-38 132.1 10.0 1.0 1 0 0 1 1 1 1 Der1-like family Arm_3 PF16186.3 MSTRG.85452.1_1 - 0.058 12.8 0.0 0.18 11.3 0.2 1.6 2 0 0 2 2 2 0 Atypical Arm repeat Tox-WTIP PF15654.4 MSTRG.110912.1_2 - 0.0099 15.7 0.2 0.014 15.2 0.2 1.2 1 0 0 1 1 1 1 Toxin with a conserved tryptophan and TIP tripeptide motif PAS PF00989.23 MSTRG.111123.2_2 - 5.5e-12 45.6 0.0 1.6e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.10 MSTRG.111123.2_2 - 7e-11 42.1 0.0 0.00011 22.2 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 MSTRG.111123.2_2 - 5.4e-10 39.2 0.1 1.4e-05 25.0 0.0 2.5 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.8 MSTRG.111123.2_2 - 1.4e-06 28.4 0.0 0.033 14.3 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.5 MSTRG.111123.2_2 - 4.6e-06 26.7 0.0 0.037 14.2 0.0 2.2 2 0 0 2 2 2 2 PAS domain PPR_3 PF13812.4 MSTRG.91581.1_2 - 0.03 14.3 0.1 0.037 14.0 0.1 1.1 1 0 0 1 1 1 0 Pentatricopeptide repeat domain 7tm_1 PF00001.19 MSTRG.46221.1_3 - 9e-10 38.1 3.6 9.6e-10 38.0 3.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MGTL PF17059.3 MSTRG.114080.1_3 - 0.1 12.3 1.0 0.2 11.3 1.0 1.5 1 0 0 1 1 1 0 MgtA leader peptide Y_phosphatase PF00102.25 MSTRG.99606.1_3 - 1.7e-16 60.4 0.0 2.1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RVT_1 PF00078.25 MSTRG.114628.1_3 - 1.1e-13 51.1 0.0 1.5e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.23 MSTRG.36714.1_3 - 0.0059 15.9 0.0 0.0072 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1376 PF07120.9 MSTRG.36714.1_3 - 0.051 13.7 0.2 0.073 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) DBB PF14545.4 MSTRG.20082.1_3 - 3.2e-11 43.2 0.0 4.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, TSP_1 PF00090.17 MSTRG.137688.1_2 - 2.8e-83 273.8 84.0 1.5e-16 60.2 8.3 6.8 6 0 0 6 6 6 6 Thrombospondin type 1 domain Spond_N PF06468.11 MSTRG.137688.1_2 - 1e-68 231.2 0.1 2.1e-68 230.1 0.0 1.6 2 0 0 2 2 2 1 Spondin_N Sema PF01403.17 MSTRG.12976.1_2 - 0.0001 21.1 0.0 0.00012 20.9 0.0 1.0 1 0 0 1 1 1 1 Sema domain HLH PF00010.24 MSTRG.74202.1_3 - 9.6e-17 60.6 0.4 1.9e-16 59.7 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UPF0564 PF10595.7 MSTRG.74202.1_3 - 0.0032 16.4 3.8 0.0046 15.9 3.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 MITF_TFEB_C_3_N PF15951.3 MSTRG.74202.1_3 - 0.018 15.5 0.1 0.018 15.5 0.1 2.3 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus DUF5300 PF17224.1 MSTRG.74202.1_3 - 0.091 12.9 0.2 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) 5_nucleotid PF05761.12 MSTRG.90257.1_2 - 8e-23 80.9 0.1 9.1e-23 80.7 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family Pkinase_Tyr PF07714.15 MSTRG.64512.1_3 - 0.11 11.6 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase MFS_1 PF07690.14 MSTRG.140983.1_2 - 0.0001 21.2 6.0 0.00078 18.3 6.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily ThrE_2 PF12821.5 MSTRG.140983.1_2 - 0.026 14.5 0.2 0.047 13.7 0.2 1.4 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE Sugar_tr PF00083.22 MSTRG.140983.1_2 - 0.064 12.0 1.7 0.71 8.5 0.1 2.0 1 1 1 2 2 2 0 Sugar (and other) transporter Vma12 PF11712.6 MSTRG.126691.1_3 - 1.8e-22 79.8 0.4 2.7e-22 79.1 0.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Polysacc_synt PF01943.15 MSTRG.126691.1_3 - 0.012 14.9 0.9 0.018 14.3 0.9 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RVT_1 PF00078.25 MSTRG.126030.1_3 - 1.8e-05 24.3 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jnk-SapK_ap_N PF09744.7 MSTRG.48375.1_2 - 8.7e-31 107.1 34.0 5.5e-30 104.5 20.9 2.7 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 RILP PF11461.6 MSTRG.48375.1_2 - 2.8e-20 72.2 1.8 2.8e-20 72.2 1.8 3.7 3 1 1 4 4 4 1 Rab interacting lysosomal protein Fib_alpha PF08702.8 MSTRG.48375.1_2 - 0.0054 16.8 8.4 0.0054 16.8 8.4 2.7 3 0 0 3 3 3 2 Fibrinogen alpha/beta chain family Speriolin_C PF15059.4 MSTRG.48375.1_2 - 0.23 11.4 4.3 0.13 12.3 0.7 2.3 1 1 0 2 2 2 0 Speriolin C-terminus ATG16 PF08614.9 MSTRG.48375.1_2 - 1.3 9.0 43.2 0.053 13.6 26.5 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) AKNA PF12443.6 MSTRG.48375.1_2 - 3.1 8.4 15.7 2.6 8.6 12.3 2.5 1 1 1 2 2 2 0 AT-hook-containing transcription factor YflT PF11181.6 MSTRG.48375.1_2 - 4.9 7.6 9.9 0.21 12.0 1.5 3.1 3 2 2 5 5 5 0 Heat induced stress protein YflT PH_12 PF16457.3 MSTRG.22862.1_3 - 0.0038 17.6 0.0 0.0054 17.1 0.0 1.3 1 1 0 1 1 1 1 Pleckstrin homology domain LRR_8 PF13855.4 MSTRG.17171.1_3 - 2.5e-16 59.0 11.3 1.4e-11 43.8 3.3 2.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.5 MSTRG.17171.1_3 - 7.8e-14 51.4 17.6 5.7e-06 26.4 0.9 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 MSTRG.17171.1_3 - 9.8e-08 31.3 2.0 0.46 11.0 0.1 4.3 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.4 MSTRG.17171.1_3 - 8.9e-05 22.1 4.2 5.1 7.3 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_9 PF14580.4 MSTRG.17171.1_3 - 0.00084 18.7 2.9 0.052 12.9 0.7 2.0 1 1 1 2 2 2 2 Leucine-rich repeat bZIP_Maf PF03131.15 MSTRG.38006.1_3 - 1.9e-31 108.3 11.4 2.5e-31 107.9 11.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor JIP_LZII PF16471.3 MSTRG.38006.1_3 - 0.024 14.7 1.2 0.047 13.7 1.2 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.19 MSTRG.38006.1_3 - 0.045 13.7 14.5 0.15 12.1 14.5 1.8 1 1 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.3 MSTRG.38006.1_3 - 0.075 13.0 1.4 0.13 12.2 1.4 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.13 MSTRG.38006.1_3 - 0.13 11.9 7.5 0.088 12.5 5.5 1.7 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.13 MSTRG.38006.1_3 - 0.31 11.0 11.8 0.69 9.9 11.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DASH_Spc19 PF08287.9 MSTRG.38006.1_3 - 0.95 9.3 6.8 1.5 8.6 6.8 1.2 1 0 0 1 1 1 0 Spc19 M PF02370.14 MSTRG.38006.1_3 - 6.2 7.6 6.9 14 6.6 6.9 1.6 1 0 0 1 1 1 0 M protein repeat WxL PF13731.4 MSTRG.37790.1_2 - 0.74 9.7 3.4 1.1e+02 2.5 0.0 3.7 4 0 0 4 4 4 0 WxL domain surface cell wall-binding LETM1 PF07766.11 MSTRG.124511.1_1 - 1.2e-56 191.9 0.2 1.3e-56 191.7 0.2 1.0 1 0 0 1 1 1 1 LETM1-like protein PH PF00169.27 MSTRG.123397.1_2 - 0.0014 19.0 0.1 0.0016 18.8 0.1 1.1 1 0 0 1 1 1 1 PH domain DUF4495 PF14906.4 MSTRG.123397.1_2 - 0.033 13.1 0.4 0.036 13.0 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) Collagen PF01391.16 MSTRG.13497.1_1 - 1.3e-14 53.5 57.4 1.2e-08 34.5 32.9 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MIF4G PF02854.17 MSTRG.15457.2_3 - 4.5e-25 88.4 0.1 6.5e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain FAM193_C PF15914.3 MSTRG.15457.2_3 - 0.034 13.7 2.2 0.077 12.6 2.2 1.6 1 0 0 1 1 1 0 FAM193 family C-terminal dCache_1 PF02743.16 MSTRG.15457.2_3 - 0.21 11.2 0.7 4.1 7.0 0.1 2.1 2 0 0 2 2 2 0 Cache domain Malic_M PF03949.13 MSTRG.128983.1_2 - 0.00055 19.1 0.0 0.00069 18.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain SUZ PF12752.5 MSTRG.128983.1_3 - 0.048 14.3 0.1 0.086 13.5 0.1 1.4 1 0 0 1 1 1 0 SUZ domain U79_P34 PF03064.14 MSTRG.109632.1_1 - 2.3 7.4 12.9 2.3 7.4 12.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Cir_N PF10197.7 MSTRG.109632.1_1 - 4.5 7.4 29.0 4.9 7.3 7.4 2.3 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Pox_Ag35 PF03286.12 MSTRG.41074.1_3 - 0.0098 15.6 2.0 0.013 15.2 2.0 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.8 MSTRG.41074.1_3 - 1.1 9.6 6.8 0.11 12.7 2.3 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain OLF PF02191.14 MSTRG.62349.1_2 - 2.7e-14 53.2 0.0 3e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain FUSC_2 PF13515.4 MSTRG.135202.1_3 - 0.0055 16.8 2.2 0.0067 16.5 2.2 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein-like DUF2701 PF10857.6 MSTRG.135202.1_3 - 7.2 6.6 7.1 9.1 6.3 4.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2701) V-set PF07686.15 MSTRG.87600.1_3 - 2.9e-05 24.0 0.0 3.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 MSTRG.87600.1_3 - 0.068 13.7 0.0 0.091 13.2 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Lep_receptor_Ig PF06328.9 MSTRG.87600.1_3 - 0.073 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Ig-like C2-type domain NSP10 PF09401.8 MSTRG.121315.1_3 - 0.069 13.1 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Ldl_recept_a PF00057.16 MSTRG.110505.1_1 - 3.6e-32 110.2 45.4 5.7e-12 45.5 10.1 3.1 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Inhibitor_I68 PF10468.7 MSTRG.110505.1_1 - 1.4 9.2 22.5 1.2 9.4 11.4 2.3 1 1 1 2 2 2 0 Carboxypeptidase inhibitor I68 DDE_3 PF13358.4 MSTRG.126115.1_1 - 0.00055 19.6 0.1 0.00083 19.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3252 PF11623.6 MSTRG.123346.1_3 - 0.011 15.2 4.0 26 4.4 0.1 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3252) Nsp1_C PF05064.11 MSTRG.123346.1_3 - 2.8 7.6 5.8 17 5.1 1.1 2.9 1 1 1 2 2 2 0 Nsp1-like C-terminal region Prok-E2_E PF14462.4 MSTRG.123346.1_3 - 6.2 6.6 14.3 19 4.9 14.3 2.6 1 1 0 1 1 1 0 Prokaryotic E2 family E CBM-like PF14683.4 MSTRG.123346.1_3 - 7.2 6.3 10.8 42 3.8 0.1 3.8 4 0 0 4 4 4 0 Polysaccharide lyase family 4, domain III DUF2618 PF10940.6 MSTRG.41913.1_2 - 0.13 11.9 0.8 0.13 11.9 0.8 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2618) Alpha_GJ PF03229.11 MSTRG.106676.1_3 - 7.3 7.0 7.3 1.5 9.2 0.5 2.0 1 1 1 2 2 2 0 Alphavirus glycoprotein J SURF6 PF04935.10 MSTRG.131427.1_1 - 0.0045 16.6 3.3 0.0055 16.3 3.3 1.1 1 0 0 1 1 1 1 Surfeit locus protein 6 EGF_CA PF07645.13 MSTRG.134394.1_2 - 1.4e-28 98.7 51.5 3.6e-09 36.5 7.9 4.1 4 0 0 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.5 MSTRG.134394.1_2 - 5e-22 77.4 14.9 1.9e-10 40.3 0.5 4.9 6 0 0 6 6 6 3 Complement Clr-like EGF-like FXa_inhibition PF14670.4 MSTRG.134394.1_2 - 7.5e-14 51.6 51.6 1.6e-06 28.2 7.5 4.3 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF PF00008.25 MSTRG.134394.1_2 - 1.9e-09 37.5 47.5 1.7e-05 24.8 5.2 5.5 3 3 2 5 5 5 3 EGF-like domain EGF_3 PF12947.5 MSTRG.134394.1_2 - 1.2e-08 34.8 40.5 0.0016 18.5 0.7 5.3 2 1 3 5 5 5 4 EGF domain hEGF PF12661.5 MSTRG.134394.1_2 - 0.00043 20.7 15.3 0.0049 17.4 4.9 6.9 7 1 0 7 7 7 3 Human growth factor-like EGF NKAP PF15692.3 MSTRG.135944.2_3 - 1.4e-12 48.0 12.9 1.4e-12 48.0 12.9 3.4 1 1 1 2 2 2 1 NF-kappa-B-activating protein DDHD PF02862.15 MSTRG.135944.2_3 - 1.7 8.6 10.3 2.1 8.3 10.3 1.2 1 0 0 1 1 1 0 DDHD domain HTH_38 PF13936.4 MSTRG.139904.1_3 - 2e-05 24.2 0.3 3.8e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.139904.1_3 - 0.00034 20.2 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.4 MSTRG.139904.1_3 - 0.031 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.4 MSTRG.139904.1_3 - 0.036 14.0 0.1 0.095 12.6 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix PAX PF00292.16 MSTRG.139904.1_3 - 0.061 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.139904.1_3 - 0.074 13.2 0.3 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 Transposase Ribosomal_S13_N PF08069.10 MSTRG.139904.1_3 - 0.082 12.8 2.3 0.53 10.2 0.1 2.9 2 1 1 3 3 3 0 Ribosomal S13/S15 N-terminal domain HTH_32 PF13565.4 MSTRG.139904.1_3 - 0.1 13.1 0.1 0.3 11.6 0.1 1.8 1 1 1 2 2 2 0 Homeodomain-like domain Sporozoite_P67 PF05642.9 MSTRG.73963.1_3 - 0.31 8.9 8.6 0.31 8.9 8.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SIR4_SID PF16991.3 MSTRG.73963.1_3 - 0.39 10.6 6.0 0.47 10.3 6.0 1.0 1 0 0 1 1 1 0 Sir4 SID domain Pox_RNA_Pol_19 PF05320.10 MSTRG.73963.1_3 - 0.69 9.7 4.5 0.73 9.6 4.5 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CDC45 PF02724.12 MSTRG.73963.1_3 - 0.83 7.7 8.6 0.93 7.6 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.10 MSTRG.73963.1_3 - 0.96 7.5 7.2 1 7.4 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family E1_UFD PF09358.8 MSTRG.30713.1_1 - 4.3e-20 72.1 0.0 7.6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fold domain ThiF PF00899.19 MSTRG.30713.1_1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Senescence_reg PF04520.11 MSTRG.76057.1_1 - 4.9 7.9 8.5 16 6.2 8.5 1.7 1 1 0 1 1 1 0 Senescence regulator HTH_Tnp_Tc3_2 PF01498.16 MSTRG.78356.1_3 - 8.6e-20 70.6 0.2 1.3e-19 70.1 0.2 1.3 1 0 0 1 1 1 1 Transposase DUF3176 PF11374.6 MSTRG.52080.1_3 - 0.077 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) RVT_1 PF00078.25 MSTRG.79679.1_2 - 0.01 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Jiraiya PF15038.4 MSTRG.79679.1_3 - 0.033 13.5 4.8 0.042 13.1 4.8 1.3 1 1 0 1 1 1 0 Jiraiya PUF PF00806.17 MSTRG.143002.1_1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat GAIN PF16489.3 MSTRG.18789.1_3 - 2.5e-11 43.3 0.1 2.6e-11 43.2 0.1 1.0 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain DUF4524 PF15025.4 MSTRG.18789.1_3 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) DUF2798 PF11391.6 MSTRG.97543.1_2 - 0.11 12.4 1.7 0.79 9.7 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2798) HEAT PF02985.20 MSTRG.127607.1_1 - 0.13 12.4 0.2 6.3 7.2 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat IL8 PF00048.18 MSTRG.91344.1_2 - 2.7e-18 65.7 0.4 4.3e-18 65.1 0.4 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like NeA_P2 PF12312.6 MSTRG.61339.1_2 - 0.002 17.5 0.1 0.0023 17.3 0.1 1.0 1 0 0 1 1 1 1 Nepovirus subgroup A polyprotein Sugarporin_N PF11471.6 MSTRG.61339.1_2 - 0.052 13.4 0.3 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF4229 PF14012.4 MSTRG.29937.1_1 - 6.3 6.8 7.5 7.1 6.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) TrbE PF11100.6 MSTRG.29937.1_2 - 2.3 8.4 9.8 0.11 12.5 3.5 1.9 2 0 0 2 2 2 0 Conjugal transfer protein TrbE Rer1 PF03248.11 MSTRG.69031.1_1 - 0.012 15.3 2.0 0.014 15.0 2.0 1.0 1 0 0 1 1 1 0 Rer1 family RINGv PF12906.5 MSTRG.6872.1_2 - 1e-12 47.8 10.6 2e-12 46.9 10.6 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.6 MSTRG.6872.1_2 - 0.00022 21.2 6.7 0.00035 20.6 6.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.27 MSTRG.6872.1_2 - 0.015 15.1 7.5 0.018 14.8 6.0 1.9 1 1 1 2 2 2 0 PHD-finger zf-RING_2 PF13639.4 MSTRG.6872.1_2 - 0.15 12.2 9.2 0.21 11.8 8.0 1.9 1 1 0 1 1 1 0 Ring finger domain DUF4516 PF14990.4 MSTRG.40836.1_1 - 0.48 10.1 16.3 82 2.9 0.0 6.6 8 0 0 8 8 8 0 Domain of unknown function (DUF4516) DUF4516 PF14990.4 MSTRG.40836.1_3 - 2.3 7.9 13.9 1.1e+02 2.5 0.1 5.9 7 0 0 7 7 7 0 Domain of unknown function (DUF4516) TMEM132D_N PF15705.3 MSTRG.14891.1_2 - 0.015 15.0 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term TEP1_N PF05386.9 MSTRG.25174.1_3 - 2.4 7.7 5.2 20 4.7 0.5 2.5 2 0 0 2 2 2 0 TEP1 N-terminal domain DDE_3 PF13358.4 MSTRG.62155.1_2 - 4e-12 46.0 0.0 6.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.16 MSTRG.62155.1_2 - 0.00057 19.9 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Transposase DUF2582 PF10771.7 MSTRG.57832.1_1 - 0.21 11.6 2.9 2.9 8.0 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix domain (DUF2582) MBDa PF16564.3 MSTRG.137276.1_3 - 0.058 13.5 0.1 0.098 12.7 0.1 1.3 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD Adeno_E3B PF03376.12 MSTRG.32647.1_1 - 0.069 13.3 3.3 0.063 13.4 2.7 1.4 1 1 0 1 1 1 0 Adenovirus E3B protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.32604.1_3 - 0.00093 19.3 0.1 0.0014 18.7 0.1 1.3 1 0 0 1 1 1 1 Transposase Ribosomal_60s PF00428.17 MSTRG.25613.1_3 - 2.2e-22 79.3 6.9 2.9e-22 78.9 6.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.51513.1_1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Transposase Roc PF08477.11 MSTRG.109555.1_2 - 2.2e-05 24.5 0.1 2.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 MSTRG.109555.1_2 - 2.8e-05 23.6 0.1 3.4e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Ras family DUF258 PF03193.14 MSTRG.109555.1_2 - 0.0045 16.8 0.3 0.0053 16.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 MSTRG.109555.1_2 - 0.041 13.8 0.2 0.053 13.5 0.2 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.4 MSTRG.109555.1_2 - 0.078 13.2 0.1 0.089 13.0 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.7 MSTRG.109555.1_2 - 0.14 11.1 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.4 MSTRG.109555.1_2 - 0.15 11.6 0.3 0.21 11.2 0.3 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain CTP_transf_like PF01467.24 MSTRG.98465.2_2 - 9.2e-21 74.4 0.1 1.1e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Gal_Lectin PF02140.16 MSTRG.83489.1_1 - 0.0015 18.7 0.2 0.0031 17.8 0.0 1.5 2 0 0 2 2 2 1 Galactose binding lectin domain tRNA_int_end_N2 PF12928.5 MSTRG.8389.1_2 - 0.024 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term RVT_1 PF00078.25 MSTRG.95708.1_1 - 2.6e-21 76.1 0.1 3.8e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.95708.1_2 - 8.5e-09 35.4 0.5 2.4e-08 34.0 0.5 1.8 1 0 0 1 1 1 1 Transposase PBD PF00786.26 MSTRG.64650.1_3 - 1.5e-07 31.6 1.9 1.8e-07 31.3 1.0 1.7 2 1 0 2 2 2 1 P21-Rho-binding domain CH PF00307.29 MSTRG.98182.1_3 - 3.3e-09 36.8 0.0 4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF1031 PF06275.9 MSTRG.92768.1_1 - 0.015 15.4 0.4 0.022 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) TMEM100 PF16311.3 MSTRG.33099.1_1 - 0.35 10.3 1.9 0.52 9.8 1.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 MerR-DNA-bind PF09278.9 MSTRG.67965.1_3 - 0.099 13.1 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 MerR, DNA binding Ig_3 PF13927.4 MSTRG.46974.1_2 - 2.8e-10 40.5 0.5 8.9e-07 29.3 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 MSTRG.46974.1_2 - 2.3e-09 37.1 0.1 0.0001 22.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.23 MSTRG.46974.1_2 - 1.4e-06 28.2 0.1 0.0037 17.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.46974.1_2 - 2.5e-05 24.4 0.1 0.0012 19.0 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 MSTRG.46974.1_2 - 0.00059 19.8 0.1 0.47 10.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.10 MSTRG.46974.1_2 - 0.046 13.7 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain SNARE PF05739.17 MSTRG.106027.1_1 - 0.15 11.9 1.2 0.26 11.2 1.2 1.3 1 0 0 1 1 1 0 SNARE domain PDGF PF00341.15 MSTRG.15323.1_3 - 0.0041 17.3 0.4 0.0068 16.6 0.4 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain HGTP_anticodon2 PF12745.5 MSTRG.115266.1_3 - 0.0061 15.9 0.3 0.0069 15.7 0.3 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs zf-CCHC PF00098.21 MSTRG.126790.1_3 - 1.3e-05 24.9 3.0 0.0029 17.5 0.1 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.4 MSTRG.126790.1_3 - 0.013 15.2 9.5 0.019 14.6 2.3 2.3 1 1 1 2 2 2 0 Zinc knuckle FYVE_2 PF02318.14 MSTRG.126790.1_3 - 0.098 12.7 1.8 0.13 12.3 1.8 1.3 1 1 0 1 1 1 0 FYVE-type zinc finger zf-CCHC_3 PF13917.4 MSTRG.126790.1_3 - 0.21 11.4 2.8 2.1 8.3 2.8 2.0 1 1 0 1 1 1 0 Zinc knuckle Tfb2 PF03849.12 MSTRG.42669.1_3 - 3.3e-10 39.3 0.0 3.3e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 ERM PF00769.17 MSTRG.125951.1_3 - 0.0028 17.4 24.4 0.0028 17.4 24.4 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DUF4472 PF14739.4 MSTRG.125951.1_3 - 0.03 14.9 10.4 0.03 14.9 10.4 4.1 2 2 2 4 4 4 0 Domain of unknown function (DUF4472) AKNA PF12443.6 MSTRG.125951.1_3 - 0.044 14.3 17.4 0.25 11.8 0.5 4.0 2 1 0 3 3 3 0 AT-hook-containing transcription factor DUF1664 PF07889.10 MSTRG.125951.1_3 - 3 7.7 12.1 1.2 9.0 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) APG6 PF04111.10 MSTRG.125951.1_3 - 6.4 5.9 34.1 7 5.8 17.2 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF1681 PF07933.12 MSTRG.61489.1_3 - 3.8e-30 104.4 0.0 4.5e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Laminin_N PF00055.15 MSTRG.138293.1_1 - 1.3e-08 34.6 0.1 1.6e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) SERTA PF06031.11 MSTRG.96760.1_3 - 0.02 14.4 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 SERTA motif Mito_carr PF00153.25 MSTRG.181.1_2 - 2.2e-17 62.6 0.1 1.4e-10 40.8 0.0 3.3 3 0 0 3 3 3 2 Mitochondrial carrier protein Herpes_UL52 PF03121.13 MSTRG.64844.1_2 - 0.029 14.2 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase SBP56 PF05694.9 MSTRG.21336.1_2 - 0.14 10.8 0.0 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) ATE_N PF04376.11 MSTRG.87217.1_3 - 1.1e-31 108.8 5.4 2.1e-31 108.0 5.4 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF1340 PF07067.9 MSTRG.142509.1_2 - 0.0056 15.9 0.0 0.0056 15.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1340) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.98279.1_1 - 5.1e-14 52.1 1.1 5.1e-14 52.1 1.1 1.6 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.4 MSTRG.98279.1_1 - 5e-07 30.1 1.4 8.7e-07 29.3 1.3 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.4 MSTRG.98279.1_1 - 8.9e-06 25.2 0.4 0.005 16.5 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.4 MSTRG.98279.1_1 - 0.035 14.1 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Bromodomain PF00439.23 MSTRG.143971.1_3 - 5.6e-14 51.8 0.2 1.4e-13 50.6 0.1 1.6 1 1 1 2 2 2 1 Bromodomain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.8504.1_3 - 5e-07 29.7 0.2 7.3e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Transposase Guanylate_cyc_2 PF09778.7 MSTRG.64777.1_2 - 2.5e-17 62.8 0.6 2.7e-17 62.7 0.6 1.0 1 0 0 1 1 1 1 Guanylylate cyclase DUF3335 PF11814.6 MSTRG.64777.1_2 - 0.058 12.7 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family TMEM52 PF14979.4 MSTRG.64777.1_2 - 0.1 12.4 3.5 0.11 12.3 3.5 1.2 1 0 0 1 1 1 0 Transmembrane 52 HTH_Tnp_Tc3_2 PF01498.16 MSTRG.32424.1_2 - 9.8e-16 57.6 1.5 1.3e-15 57.3 0.6 1.7 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.4 MSTRG.32424.1_2 - 0.00042 19.9 2.3 0.00092 18.8 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.4 MSTRG.32424.1_2 - 0.002 18.5 0.0 0.0048 17.4 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.4 MSTRG.32424.1_2 - 0.0077 16.2 0.4 0.73 9.9 0.1 2.3 2 0 0 2 2 2 1 HTH-like domain DUF1456 PF07308.11 MSTRG.32424.1_2 - 0.034 14.3 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) GcrA PF07750.9 MSTRG.32424.1_2 - 0.057 13.7 0.1 0.081 13.2 0.1 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator DDE_Tnp_ISAZ013 PF07592.9 MSTRG.32424.1_2 - 0.09 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.32424.1_3 - 0.0026 17.8 0.1 0.0062 16.6 0.1 1.6 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.102805.1_1 - 1.1e-06 28.6 2.2 2.9e-06 27.3 2.2 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.4 MSTRG.102805.1_1 - 6e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Secretin_N_2 PF07655.11 MSTRG.122039.1_1 - 0.028 14.8 3.6 0.045 14.2 3.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Synaptobrevin PF00957.19 MSTRG.122039.1_1 - 0.54 10.0 3.8 0.56 9.9 3.0 1.4 1 1 0 1 1 1 0 Synaptobrevin Hemopexin PF00045.17 MSTRG.38399.1_2 - 4.1e-52 173.7 12.1 2.3e-13 49.7 0.1 4.2 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.6 MSTRG.38399.1_2 - 2.5e-24 84.9 0.0 3.7e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) SKG6 PF08693.8 MSTRG.38399.1_2 - 0.15 11.4 1.3 0.29 10.4 1.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain COX14 PF14880.4 MSTRG.124800.1_1 - 0.098 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly C_tripleX PF02363.17 MSTRG.48611.1_1 - 0.54 10.5 5.9 24 5.3 5.9 2.9 1 1 0 1 1 1 0 Cysteine rich repeat PHO4 PF01384.18 MSTRG.48611.1_2 - 0.37 9.6 2.1 0.36 9.7 2.1 1.1 1 0 0 1 1 1 0 Phosphate transporter family C_tripleX PF02363.17 MSTRG.48611.1_2 - 0.38 11.0 8.2 69 3.9 8.2 3.2 1 1 0 1 1 1 0 Cysteine rich repeat Peptidase_C50 PF03568.15 MSTRG.48611.1_3 - 7.6 5.4 6.4 8.6 5.2 6.4 1.1 1 0 0 1 1 1 0 Peptidase family C50 DUF1616 PF07760.9 MSTRG.48611.1_3 - 9.4 5.4 5.7 13 5.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.61115.1_2 - 2.8e-14 53.0 0.4 5.1e-14 52.2 0.1 1.6 2 0 0 2 2 2 1 Transposase API5 PF05918.9 MSTRG.89672.1_2 - 2.5e-44 151.8 0.1 3.1e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.4 MSTRG.89672.1_2 - 0.069 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 HEAT repeats Metallothio_11 PF02066.13 MSTRG.100873.1_1 - 0.012 15.7 2.0 0.028 14.5 2.0 1.6 1 0 0 1 1 1 0 Metallothionein family 11 PRT_C PF08372.8 MSTRG.127149.1_3 - 5.8 6.5 6.7 7.5 6.2 6.7 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal RNaseH_C PF09293.8 MSTRG.45065.1_1 - 0.044 14.0 0.9 1.3 9.2 0.1 2.1 1 1 1 2 2 2 0 T4 RNase H, C terminal Viral_Beta_CD PF04530.10 MSTRG.45065.1_1 - 0.56 10.4 4.0 32 4.7 0.1 2.6 1 1 2 3 3 3 0 Viral Beta C/D like family Spidroin_MaSp PF11260.6 MSTRG.45065.1_2 - 0.045 13.9 2.0 13 6.0 0.2 2.4 1 1 0 2 2 2 0 Major ampullate spidroin 1 and 2 DUF4596 PF15363.4 MSTRG.45065.1_2 - 4.9 7.3 13.1 97 3.2 1.2 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4596) MarR PF01047.20 MSTRG.45065.1_3 - 0.016 15.0 1.0 44 4.0 0.1 4.2 1 1 4 5 5 5 0 MarR family MecA PF05389.10 MSTRG.45065.1_3 - 0.028 13.9 0.2 1.6 8.2 0.1 2.0 1 1 1 2 2 2 0 Negative regulator of genetic competence (MecA) LMWPc PF01451.19 MSTRG.45065.1_3 - 0.035 14.3 0.3 14 5.9 0.1 2.8 1 1 1 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Ribosomal_L2 PF00181.21 MSTRG.45065.1_3 - 0.16 11.8 0.8 6.6 6.6 0.2 2.3 1 1 2 3 3 3 0 Ribosomal Proteins L2, RNA binding domain zf-CCHC PF00098.21 MSTRG.88363.1_3 - 3.7 7.7 12.1 18 5.5 0.6 3.5 3 0 0 3 3 3 0 Zinc knuckle ATP-gua_PtransN PF02807.13 MSTRG.64089.1_2 - 3.3e-34 117.0 0.0 4.7e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain ATP-gua_Ptrans PF00217.17 MSTRG.64089.1_2 - 1.2e-14 54.4 0.0 1.7e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain Secretin_N PF03958.15 MSTRG.64089.1_2 - 0.039 14.2 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Pkinase PF00069.23 MSTRG.121904.1_1 - 4.7e-42 144.0 1.5 5.4e-42 143.8 1.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.121904.1_1 - 4.5e-24 85.0 0.3 6e-24 84.6 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 MSTRG.121904.1_1 - 0.012 14.8 0.1 0.88 8.7 0.3 2.2 1 1 1 2 2 2 0 Kinase-like APH PF01636.21 MSTRG.121904.1_1 - 0.1 12.4 0.2 0.72 9.6 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C6H2 PF15801.3 MSTRG.117179.2_2 - 3.1e-21 75.3 10.2 4e-21 74.9 10.2 1.2 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.16 MSTRG.117179.2_2 - 0.00011 22.1 7.3 0.00024 21.0 7.3 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.14 MSTRG.117179.2_2 - 0.22 11.3 6.3 0.37 10.6 6.3 1.4 1 0 0 1 1 1 0 HIT zinc finger HTH_38 PF13936.4 MSTRG.22422.1_2 - 2.7e-05 23.7 0.1 4.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.22422.1_2 - 0.0098 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Ribosomal_S13_N PF08069.10 MSTRG.22422.1_2 - 0.071 13.0 0.3 0.6 10.1 0.1 2.4 1 1 1 2 2 2 0 Ribosomal S13/S15 N-terminal domain EMP70 PF02990.14 MSTRG.125728.1_3 - 2.6e-26 92.2 0.1 3.1e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EF-hand_8 PF13833.4 MSTRG.87631.1_2 - 1.1e-05 24.9 1.7 4.6e-05 23.0 0.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.4 MSTRG.87631.1_2 - 0.00014 22.1 2.0 0.0002 21.6 1.3 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.30 MSTRG.87631.1_2 - 0.0013 18.0 1.2 0.0082 15.5 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.4 MSTRG.87631.1_2 - 0.078 12.8 0.1 0.078 12.8 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain CDK2AP PF09806.7 MSTRG.118602.1_2 - 2.4e-20 73.5 0.3 3.5e-20 72.9 0.3 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein GrpE PF01025.17 MSTRG.10461.1_3 - 1.1e-31 109.6 0.0 1.5e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 GrpE BAR_3 PF16746.3 MSTRG.10461.1_3 - 0.016 14.7 0.4 0.023 14.3 0.4 1.1 1 0 0 1 1 1 0 BAR domain of APPL family Laminin_I PF06008.12 MSTRG.10461.1_3 - 0.026 14.1 0.6 0.037 13.6 0.6 1.2 1 0 0 1 1 1 0 Laminin Domain I CLZ PF16526.3 MSTRG.10461.1_3 - 0.04 14.1 2.3 0.052 13.8 0.7 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SOG2 PF10428.7 MSTRG.10461.1_3 - 0.046 12.8 0.1 0.056 12.6 0.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Spt5_N PF11942.6 MSTRG.10461.1_3 - 0.065 14.1 0.4 0.12 13.2 0.4 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4201 PF13870.4 MSTRG.10461.1_3 - 0.066 12.7 0.9 0.11 12.0 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) E2F_CC-MB PF16421.3 MSTRG.10461.1_3 - 0.14 12.5 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain GAS PF13851.4 MSTRG.10461.1_3 - 0.98 8.6 3.8 2.8 7.1 1.2 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding PDZ PF00595.22 MSTRG.90652.1_1 - 1.6e-17 63.4 0.6 2.7e-17 62.7 0.6 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.15 MSTRG.90652.1_1 - 1.2e-07 31.2 0.0 2.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 MSTRG.90652.1_1 - 1.7e-06 27.3 2.3 1.6e-05 24.3 2.3 2.5 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.4 MSTRG.90652.1_1 - 0.0027 17.9 0.1 0.0066 16.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.4 MSTRG.90652.1_1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Cyt_b-c1_8 PF10890.6 MSTRG.57815.1_2 - 0.0025 18.0 0.2 0.39 11.0 0.1 2.2 2 0 0 2 2 2 2 Cytochrome b-c1 complex subunit 8 Glyco_hydro_2_C PF02836.15 MSTRG.10623.2_1 - 0.0096 14.9 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Tetraspannin PF00335.18 MSTRG.50257.2_2 - 5.1e-06 26.3 6.8 1.3e-05 25.0 6.8 1.7 1 0 0 1 1 1 1 Tetraspanin family Tetraspannin PF00335.18 MSTRG.50257.2_3 - 9e-33 113.7 6.3 9e-33 113.7 6.3 1.7 2 0 0 2 2 2 1 Tetraspanin family DUF973 PF06157.9 MSTRG.50257.2_3 - 0.36 9.7 7.1 0.53 9.2 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) G-patch PF01585.21 MSTRG.135604.1_1 - 1.5e-13 50.2 4.0 2.6e-13 49.5 4.0 1.4 1 0 0 1 1 1 1 G-patch domain R3H PF01424.20 MSTRG.135604.1_1 - 4.1e-11 42.6 0.1 8.2e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 R3H domain dsrm PF00035.24 MSTRG.135604.1_1 - 3.9e-10 40.1 0.4 0.00036 21.0 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif G-patch_2 PF12656.5 MSTRG.135604.1_1 - 4.8e-06 26.4 2.3 1.3e-05 25.1 2.3 1.7 1 0 0 1 1 1 1 G-patch domain EMP24_GP25L PF01105.22 MSTRG.135604.1_1 - 0.025 14.4 3.6 0.34 10.7 0.2 2.7 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD TEX15 PF15326.4 MSTRG.13060.1_2 - 1.2e-38 133.1 1.8 1.2e-38 133.1 1.8 3.4 2 1 1 3 3 3 1 Testis expressed sequence 15 DUF3172 PF11371.6 MSTRG.13060.1_2 - 0.048 13.2 2.5 0.54 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) DOT1 PF08123.11 MSTRG.13060.1_2 - 0.39 10.1 7.2 0.11 11.9 0.9 2.3 2 0 0 2 2 2 0 Histone methylation protein DOT1 VEGF_C PF14554.4 MSTRG.95253.1_2 - 7.9e-27 93.0 24.0 1.3e-26 92.3 24.0 1.3 1 0 0 1 1 1 1 VEGF heparin-binding domain NIF PF03031.16 MSTRG.25058.1_3 - 5.5e-34 117.1 0.0 8.7e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4366 PF14283.4 MSTRG.25058.1_3 - 0.011 15.1 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3464 PF11947.6 MSTRG.25058.1_3 - 0.035 13.7 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) dDENN PF03455.17 MSTRG.101993.1_2 - 5.7e-19 67.7 3.0 8.3e-19 67.2 3.0 1.3 1 0 0 1 1 1 1 dDENN domain RBD-FIP PF09457.8 MSTRG.84735.1_2 - 2.7e-13 49.5 0.2 2.7e-13 49.5 0.2 1.7 2 0 0 2 2 2 1 FIP domain Phi-29_GP16_7 PF06720.9 MSTRG.84735.1_2 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 HTH_Tnp_Tc3_2 PF01498.16 MSTRG.97415.1_3 - 1.4e-10 41.1 1.2 1.4e-10 41.1 1.2 1.5 2 0 0 2 2 2 1 Transposase POLO_box PF00659.16 MSTRG.97415.1_3 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 2 0 0 2 2 2 0 POLO box duplicated region DUF3310 PF11753.6 MSTRG.42999.1_1 - 1.4 9.0 3.1 1.7 8.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) Sarcolipin PF05366.9 MSTRG.122387.1_3 - 0.016 14.8 1.2 0.051 13.1 1.3 1.8 2 0 0 2 2 2 0 Sarcolipin DDE_3 PF13358.4 MSTRG.26715.1_1 - 0.001 18.7 0.1 0.0019 17.9 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Tissue_fac PF01108.15 MSTRG.30242.1_2 - 1.6e-06 27.7 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Tissue factor UCH PF00443.27 MSTRG.40543.1_1 - 1.5e-07 31.1 0.5 1.7e-07 30.9 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sigma70_r4 PF04545.14 MSTRG.114834.1_3 - 0.061 12.7 0.3 0.088 12.2 0.3 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 CBFD_NFYB_HMF PF00808.21 MSTRG.29217.2_1 - 5.6e-22 77.7 1.6 8.8e-22 77.0 1.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 MSTRG.29217.2_1 - 4e-16 59.5 0.4 5.3e-16 59.1 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.8 MSTRG.29217.2_1 - 0.017 15.3 0.1 0.026 14.7 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X SWIRM-assoc_2 PF16496.3 MSTRG.27632.1_2 - 0.18 10.5 15.6 0.2 10.4 15.6 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4887 PF16228.3 MSTRG.27632.1_2 - 0.81 9.5 21.4 1.1 9.0 21.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4887) CiPC PF15800.3 MSTRG.27632.1_2 - 3.2 7.3 14.3 3.5 7.1 14.3 1.0 1 0 0 1 1 1 0 Clock interacting protein circadian Plasmodium_Vir PF05795.9 MSTRG.27632.1_2 - 4 6.6 11.0 4.4 6.5 11.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NARP1 PF12569.6 MSTRG.27632.1_2 - 6.7 5.3 9.8 7.7 5.1 9.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.8 MSTRG.27632.1_2 - 8.2 6.4 9.2 11 6.0 9.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HTH_Tnp_Tc3_2 PF01498.16 MSTRG.50529.1_1 - 0.023 14.8 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.50529.1_3 - 1.2e-09 38.2 0.5 1.5e-09 37.8 0.5 1.1 1 0 0 1 1 1 1 Transposase GYR PF02756.12 MSTRG.50529.1_3 - 0.45 10.1 8.4 1.1 8.9 8.4 1.7 1 1 0 1 1 1 0 GYR motif Nucleoside_tran PF01733.16 MSTRG.5164.1_3 - 0.0078 15.5 0.1 0.0082 15.4 0.1 1.0 1 0 0 1 1 1 1 Nucleoside transporter DUF3915 PF13054.4 MSTRG.5164.1_3 - 0.08 12.8 2.0 0.11 12.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Cucumo_2B PF03263.11 MSTRG.5164.1_3 - 0.22 11.9 3.6 0.3 11.4 3.6 1.2 1 0 0 1 1 1 0 Cucumovirus protein 2B Atrophin-1 PF03154.13 MSTRG.5164.1_3 - 6.4 4.8 8.4 7.7 4.5 8.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family RGS PF00615.17 MSTRG.21036.1_2 - 1.1e-05 25.6 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain G5 PF07501.10 MSTRG.101790.1_3 - 0.12 12.7 0.3 0.12 12.7 0.3 1.6 2 0 0 2 2 2 0 G5 domain PMT PF02366.16 MSTRG.71451.1_1 - 4.2e-16 59.1 4.8 5.2e-16 58.8 4.8 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Spore_YhaL PF14147.4 MSTRG.71451.1_1 - 0.24 11.0 0.7 0.37 10.4 0.7 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL PMT PF02366.16 MSTRG.71451.1_2 - 4.7e-05 23.0 0.7 5.3e-05 22.8 0.7 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ribosomal_S13_N PF08069.10 MSTRG.120478.1_2 - 0.015 15.2 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Peptidase_M14 PF00246.22 MSTRG.94076.1_1 - 1.6e-45 156.1 0.1 2.7e-45 155.3 0.1 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.23 MSTRG.94076.1_1 - 4.5e-26 91.3 2.0 4.6e-26 91.3 0.2 1.8 2 0 0 2 2 2 1 F5/8 type C domain Ly-6_related PF06579.10 MSTRG.1070.1_3 - 0.03 14.4 0.2 0.031 14.4 0.2 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein Sulfotransfer_1 PF00685.25 MSTRG.125752.1_1 - 2.9e-73 246.5 0.1 3.9e-73 246.1 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 MSTRG.125752.1_1 - 5.1e-06 26.9 0.1 0.0005 20.4 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family AMP-binding_C PF13193.4 MSTRG.62652.1_2 - 2.3e-06 28.4 0.0 6.7e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.26 MSTRG.62652.1_2 - 0.074 11.5 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme CH PF00307.29 MSTRG.14232.1_3 - 6.4e-29 100.2 2.2 3.5e-21 75.3 0.8 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.6 MSTRG.14232.1_3 - 0.00046 19.8 0.0 0.78 9.5 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.9 MSTRG.14232.1_3 - 0.00071 19.5 0.1 0.4 10.7 0.1 2.3 2 0 0 2 2 2 2 CH-like domain in sperm protein Filament PF00038.19 MSTRG.59040.11_2 - 1.2e-30 107.1 1.3 1.3e-30 107.0 1.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein VacA2 PF03077.12 MSTRG.59040.11_2 - 0.86 9.4 4.7 0.73 9.6 2.4 2.0 2 0 0 2 2 2 0 Putative vacuolating cytotoxin Borrelia_rep PF03183.11 MSTRG.55607.1_2 - 0.018 14.9 3.6 0.032 14.1 3.6 1.4 1 0 0 1 1 1 0 Borrelia repeat protein GED PF02212.16 MSTRG.17280.3_2 - 0.086 12.9 0.9 1.3 9.1 0.1 2.5 2 1 1 3 3 3 0 Dynamin GTPase effector domain DUF288 PF03385.15 MSTRG.52007.2_2 - 0.18 10.5 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF288 Inositol_P PF00459.23 MSTRG.67400.1_1 - 0.051 13.0 2.6 0.26 10.6 1.7 2.1 1 1 0 1 1 1 0 Inositol monophosphatase family E_Pc_C PF06752.10 MSTRG.62648.1_3 - 9.1e-26 91.2 24.7 9.1e-26 91.2 24.7 1.8 2 0 0 2 2 2 1 Enhancer of Polycomb C-terminus DUF2514 PF10721.7 MSTRG.62648.1_3 - 0.041 13.8 4.2 0.067 13.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Activator_LAG-3 PF11498.6 MSTRG.62648.1_3 - 3.3 6.5 15.9 4.6 6.0 15.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4944 PF16302.3 MSTRG.19133.1_1 - 0.078 12.9 0.1 0.092 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) Metallophos PF00149.26 MSTRG.2490.1_3 - 1.3e-35 123.7 0.1 1.6e-35 123.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.19 MSTRG.132601.1_3 - 1.2e-59 200.6 0.0 1.7e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.18 MSTRG.132601.1_3 - 5.3e-07 29.0 0.0 3.1e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.8 MSTRG.132601.1_3 - 1.7e-06 27.5 0.0 2.4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.11 MSTRG.132601.1_3 - 6.6e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.21 MSTRG.132601.1_3 - 0.00039 20.4 0.0 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.20 MSTRG.132601.1_3 - 0.00064 19.2 0.0 0.00093 18.7 0.0 1.2 1 0 0 1 1 1 1 Ras family zf-CHY PF05495.10 MSTRG.6801.1_3 - 0.016 15.7 2.9 0.022 15.2 2.9 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-CHC2 PF01807.18 MSTRG.6801.1_3 - 0.021 14.5 0.3 0.027 14.1 0.3 1.1 1 0 0 1 1 1 0 CHC2 zinc finger gp12-short_mid PF09089.8 MSTRG.77712.1_3 - 0.61 10.2 3.8 17 5.5 0.3 2.6 2 1 1 3 3 3 0 Phage short tail fibre protein gp12, middle domain tRNA-synt_1c PF00749.19 MSTRG.125763.2_3 - 6.1e-80 268.3 0.3 9e-80 267.8 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.13 MSTRG.125763.2_3 - 9.4e-50 168.6 0.0 1.4e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.13 MSTRG.125763.2_3 - 3e-28 98.4 2.2 7.3e-28 97.2 2.2 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 SIMPL PF04402.12 MSTRG.125763.2_3 - 0.13 12.6 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF541) zf-C2H2_9 PF16293.3 MSTRG.113707.1_3 - 0.011 15.5 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) HMMR_N PF15905.3 MSTRG.80987.1_1 - 0.0037 16.7 12.8 0.0041 16.5 12.8 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal TetR PF13972.4 MSTRG.80987.1_1 - 0.005 16.4 1.5 0.006 16.2 1.5 1.1 1 0 0 1 1 1 1 Bacterial transcriptional repressor THOC7 PF05615.11 MSTRG.80987.1_1 - 0.0089 16.2 12.5 0.011 15.9 12.5 1.1 1 0 0 1 1 1 1 Tho complex subunit 7 GAS PF13851.4 MSTRG.80987.1_1 - 0.023 14.0 17.3 0.099 11.9 11.3 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DMPK_coil PF08826.8 MSTRG.80987.1_1 - 0.05 13.6 0.6 0.05 13.6 0.6 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF489 PF04356.10 MSTRG.80987.1_1 - 0.058 13.3 2.4 0.074 12.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Golgin_A5 PF09787.7 MSTRG.80987.1_1 - 0.12 11.7 15.9 0.14 11.5 15.9 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fib_alpha PF08702.8 MSTRG.80987.1_1 - 0.19 11.8 7.1 0.22 11.6 7.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.4 MSTRG.80987.1_1 - 0.19 12.1 13.6 1.7 9.0 7.5 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Alanine_zipper PF11839.6 MSTRG.80987.1_1 - 0.21 11.8 8.1 0.26 11.5 8.1 1.2 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Spc7 PF08317.9 MSTRG.80987.1_1 - 0.21 10.3 13.6 0.24 10.1 13.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.13 MSTRG.80987.1_1 - 0.28 10.6 6.7 0.31 10.4 6.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit IF-2B PF01008.15 MSTRG.80987.1_1 - 0.29 10.2 3.8 0.36 9.9 3.8 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family APG6 PF04111.10 MSTRG.80987.1_1 - 0.35 10.1 16.2 0.39 9.9 16.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.17 MSTRG.80987.1_1 - 0.38 8.5 8.1 0.41 8.4 8.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HisKA_3 PF07730.11 MSTRG.80987.1_1 - 0.75 10.2 10.6 3.9 7.9 4.2 2.1 1 1 1 2 2 2 0 Histidine kinase ERM PF00769.17 MSTRG.80987.1_1 - 0.79 9.4 24.1 1 9.0 24.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF883 PF05957.11 MSTRG.80987.1_1 - 1.1 9.7 11.5 1.4 9.4 6.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF342 PF03961.11 MSTRG.80987.1_1 - 1.5 7.2 9.1 1.7 7.0 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_9 PF12781.5 MSTRG.80987.1_1 - 2.6 7.0 9.2 2.4 7.1 8.4 1.3 1 1 0 1 1 1 0 ATP-binding dynein motor region D5 DUF4407 PF14362.4 MSTRG.80987.1_1 - 2.8 7.1 9.0 3.8 6.6 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4164 PF13747.4 MSTRG.80987.1_1 - 3.2 8.0 15.8 3.2 8.0 11.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TMPIT PF07851.11 MSTRG.80987.1_1 - 4.8 6.2 8.4 5.8 5.9 8.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.14 MSTRG.80987.1_1 - 5.8 5.6 5.5 6.9 5.3 5.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FimH_man-bind PF09160.8 MSTRG.88682.1_3 - 4.7e-05 23.0 0.0 0.00045 19.8 0.1 2.0 2 0 0 2 2 2 1 FimH, mannose binding Use1 PF09753.7 MSTRG.70280.1_2 - 0.18 11.3 0.0 0.2 11.2 0.0 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 DOR PF14839.4 MSTRG.70280.1_2 - 2.9 7.6 6.2 1.9 8.2 4.6 1.5 1 1 0 1 1 1 0 DOR family YiiD_C PF09500.8 MSTRG.65891.1_3 - 0.0075 16.0 0.1 0.016 14.9 0.0 1.5 2 0 0 2 2 2 1 Putative thioesterase (yiiD_Cterm) PspB PF06667.10 MSTRG.99413.1_2 - 1.2 9.1 2.9 1.8 8.5 2.9 1.3 1 0 0 1 1 1 0 Phage shock protein B Dimer_Tnp_hAT PF05699.12 MSTRG.41335.1_1 - 7.2e-06 25.6 0.0 8.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Dpy19 PF10034.7 MSTRG.73752.1_2 - 1.3e-21 76.4 0.3 1.4e-21 76.3 0.3 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Sugar_tr PF00083.22 MSTRG.90989.1_1 - 7.1e-21 74.4 0.2 7.4e-21 74.4 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 MSTRG.90989.1_1 - 0.001 17.9 1.6 0.0012 17.7 1.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MbtH PF03621.11 MSTRG.36402.1_3 - 2.7 7.4 7.7 1.6 8.1 0.4 3.0 2 1 0 2 2 2 0 MbtH-like protein zf-H2C2_2 PF13465.4 MSTRG.23934.1_1 - 1.1 9.8 4.0 2.2 8.8 2.2 2.1 2 0 0 2 2 2 0 Zinc-finger double domain NDUFV3 PF15880.3 MSTRG.23934.1_2 - 9.7e-18 63.8 1.8 1.9e-17 62.8 1.8 1.5 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial UPF0061 PF02696.12 MSTRG.10576.1_2 - 2.1e-38 132.2 0.0 2.3e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TPKR_C2 PF16920.3 MSTRG.73189.1_2 - 0.045 13.8 1.4 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain BRO1 PF03097.16 MSTRG.104983.1_1 - 2.2e-29 102.3 0.4 2.5e-29 102.2 0.4 1.0 1 0 0 1 1 1 1 BRO1-like domain DUF4807 PF16065.3 MSTRG.104983.1_1 - 0.089 12.4 0.2 0.78 9.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4807) GMC_oxred_N PF00732.17 MSTRG.36082.1_3 - 0.019 14.2 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Caldesmon PF02029.13 MSTRG.84192.3_2 - 8.5e-44 150.0 56.3 2.8e-43 148.3 56.3 1.7 1 1 0 1 1 1 1 Caldesmon KAP_NTPase PF07693.12 MSTRG.19418.1_1 - 1.5e-37 129.5 0.0 1.6e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 KAP family P-loop domain Zeta_toxin PF06414.10 MSTRG.19418.1_1 - 0.059 12.5 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin IncA PF04156.12 MSTRG.19418.1_1 - 2.8 7.6 3.9 4.6 6.9 3.9 1.3 1 0 0 1 1 1 0 IncA protein SAM_1 PF00536.28 MSTRG.129033.1_1 - 2.3e-12 47.0 0.1 2.9e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 MSTRG.129033.1_1 - 1.5e-07 31.3 0.0 2.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.115828.1_1 - 0.0015 18.6 0.7 0.0015 18.6 0.7 1.7 2 0 0 2 2 2 1 Transposase UCR_6-4kD PF08997.8 MSTRG.62630.1_2 - 0.065 13.1 0.1 0.094 12.5 0.1 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DUF3561 PF12084.6 MSTRG.78922.1_2 - 0.73 9.7 6.5 0.86 9.5 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) Tcf25 PF04910.12 MSTRG.21606.1_3 - 1.1e-48 166.0 0.1 1.2e-48 165.8 0.1 1.0 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Arm_3 PF16186.3 MSTRG.83758.1_2 - 4.9e-23 80.3 3.7 7.1e-23 79.8 3.7 1.2 1 0 0 1 1 1 1 Atypical Arm repeat Arm PF00514.21 MSTRG.83758.1_2 - 1.9e-10 40.3 3.0 1e-05 25.2 0.1 3.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.4 MSTRG.83758.1_2 - 0.043 14.1 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 HEAT-like repeat DUF3915 PF13054.4 MSTRG.118563.1_3 - 2.9 7.8 6.5 3.7 7.4 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RVT_1 PF00078.25 MSTRG.41670.1_3 - 1e-14 54.5 0.0 1.1e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACBP PF00887.17 MSTRG.108440.1_1 - 3.9e-15 55.7 0.0 5.8e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein FBPase_2 PF06874.9 MSTRG.108440.1_1 - 0.1 10.7 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Peptidase_M10 PF00413.22 MSTRG.111690.1_3 - 1.1e-29 103.2 0.0 1.5e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.16 MSTRG.111690.1_3 - 1.6e-11 44.1 0.1 4.1e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain HTH_28 PF13518.4 MSTRG.3898.1_1 - 0.00049 20.0 0.6 0.0007 19.5 0.6 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.3898.1_1 - 0.00076 19.1 0.3 0.001 18.6 0.3 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.13 MSTRG.3898.1_1 - 0.0026 17.7 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase CENP-B_N PF04218.11 MSTRG.3898.1_1 - 0.003 17.0 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.4 MSTRG.3898.1_1 - 0.0031 17.2 0.1 0.004 16.8 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.16 MSTRG.3898.1_1 - 0.0038 17.0 0.1 0.0045 16.7 0.1 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_Tnp_ISL3 PF13542.4 MSTRG.3898.1_1 - 0.0061 15.8 1.8 0.0097 15.2 1.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.4 MSTRG.3898.1_1 - 0.012 15.5 0.3 0.02 14.8 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.4 MSTRG.3898.1_1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding XRCC1_N PF01834.14 MSTRG.66251.1_3 - 4.7e-49 166.2 0.1 5.2e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 XRCC1 N terminal domain F5_F8_type_C PF00754.23 MSTRG.66251.1_3 - 0.054 13.5 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain Peptidase_M41 PF01434.16 MSTRG.81511.1_3 - 0.0091 15.5 0.3 0.011 15.3 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M41 VIT PF08487.8 MSTRG.143506.1_2 - 1.6e-34 118.4 0.0 1.9e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.4 MSTRG.143506.1_2 - 2.8e-14 52.6 0.1 3.9e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain AIG1 PF04548.14 MSTRG.65557.1_2 - 1.1e-38 132.6 1.7 1.1e-38 132.6 1.7 2.0 1 1 1 2 2 2 1 AIG1 family DUF3552 PF12072.6 MSTRG.65557.1_2 - 6.3e-05 22.4 14.2 0.00012 21.4 14.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) DUF260 PF03195.12 MSTRG.65557.1_2 - 0.0067 16.7 1.0 0.028 14.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF260 Spc7 PF08317.9 MSTRG.65557.1_2 - 0.01 14.6 23.9 0.063 12.0 17.4 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein T3SSipB PF16535.3 MSTRG.65557.1_2 - 0.013 15.9 8.1 0.013 15.9 8.1 1.7 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF3802 PF12290.6 MSTRG.65557.1_2 - 0.025 15.0 0.6 0.025 15.0 0.6 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3802) DUF4407 PF14362.4 MSTRG.65557.1_2 - 0.081 12.1 10.0 0.11 11.7 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG5 PF10392.7 MSTRG.65557.1_2 - 0.12 12.4 7.6 0.091 12.8 4.2 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 HemX PF04375.12 MSTRG.65557.1_2 - 0.76 8.9 12.7 0.2 10.8 8.7 1.8 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4200 PF13863.4 MSTRG.65557.1_2 - 2.9 8.2 26.7 2 8.7 22.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) LMBR1 PF04791.14 MSTRG.65557.1_2 - 3.3 6.4 8.1 3.9 6.1 8.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NPV_P10 PF05531.10 MSTRG.65557.1_2 - 3.6 8.0 8.8 7.9 6.9 3.5 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.10 MSTRG.65557.1_2 - 4.2 7.2 13.2 1.6 8.6 7.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Antimicrobial19 PF08225.9 MSTRG.60339.1_1 - 6.4 6.4 9.1 1.2e+02 2.3 0.1 5.5 4 1 2 7 7 7 0 Pseudin antimicrobial peptide Antimicrobial19 PF08225.9 MSTRG.60339.1_2 - 0.008 15.6 7.5 51 3.5 0.1 6.7 3 3 4 7 7 7 2 Pseudin antimicrobial peptide ITAM PF02189.13 MSTRG.60339.1_2 - 1.2 9.7 9.7 1.9e+02 2.7 0.0 6.1 6 0 0 6 6 6 0 Immunoreceptor tyrosine-based activation motif SepZ PF06066.9 MSTRG.60339.1_3 - 0.017 15.2 0.2 2.9 8.0 0.0 3.7 2 1 2 4 4 4 0 SepZ Corona_NS4 PF03905.11 MSTRG.60339.1_3 - 0.85 9.5 15.0 25 4.8 0.2 6.4 5 2 3 8 8 8 0 Coronavirus non-structural protein NS4 UCH PF00443.27 MSTRG.140017.1_3 - 2.4e-18 66.4 0.0 3e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Terminase_5 PF06056.10 MSTRG.140017.1_3 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Papilloma_E5 PF03025.12 MSTRG.28366.1_2 - 2.2 8.4 12.3 8.7 6.4 12.0 1.9 1 1 1 2 2 2 0 Papillomavirus E5 Crisp PF08562.8 MSTRG.15084.1_1 - 0.18 12.3 1.3 0.18 12.3 1.3 2.2 2 0 0 2 2 2 0 Crisp AMP-binding PF00501.26 MSTRG.15084.1_3 - 4.2e-22 78.2 0.0 4.5e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Pea-VEAacid PF08111.9 MSTRG.95751.1_1 - 8 6.9 8.7 9.8 6.6 0.1 3.2 3 0 0 3 3 3 0 Pea-VEAacid family DUF4729 PF15866.3 MSTRG.97818.1_1 - 0.6 9.3 7.7 0.19 10.9 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4729) zf-C2H2 PF00096.24 MSTRG.97818.1_1 - 2.3 8.7 17.7 0.61 10.5 1.7 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type JSRP PF15312.4 MSTRG.121505.1_2 - 8.1 6.4 8.3 11 6.0 0.7 3.4 3 1 1 4 4 4 0 Junctional sarcoplasmic reticulum protein OapA_N PF08525.9 MSTRG.125425.1_2 - 0.0029 17.4 3.8 0.72 9.7 0.1 2.4 2 0 0 2 2 2 2 Opacity-associated protein A N-terminal motif TRAM_LAG1_CLN8 PF03798.14 MSTRG.15873.3_1 - 1.5e-10 41.0 5.1 1.5e-10 41.0 5.1 1.6 2 0 0 2 2 2 1 TLC domain TRAM_LAG1_CLN8 PF03798.14 MSTRG.15873.3_3 - 8.5e-12 45.1 3.2 8.5e-12 45.1 3.2 1.8 2 0 0 2 2 2 1 TLC domain REV PF00424.16 MSTRG.9447.1_2 - 0.0033 17.3 0.3 0.0083 16.0 0.1 1.8 2 0 0 2 2 2 1 REV protein (anti-repression trans-activator protein) Rap1_C PF11626.6 MSTRG.9447.1_2 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.129902.1_3 - 2.9e-11 43.3 0.7 3.8e-11 43.0 0.7 1.3 1 1 0 1 1 1 1 Transposase HTH_32 PF13565.4 MSTRG.129902.1_3 - 0.0089 16.5 1.5 0.012 16.1 1.5 1.2 1 0 0 1 1 1 1 Homeodomain-like domain PH PF00169.27 MSTRG.54786.1_1 - 8.4e-07 29.3 0.1 1.2e-06 28.9 0.1 1.2 1 0 0 1 1 1 1 PH domain Homeobox PF00046.27 MSTRG.19585.1_1 - 2.3e-15 56.0 0.0 2.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Homeobox domain C4 PF01413.17 MSTRG.19585.1_1 - 0.026 14.8 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 C-terminal tandem repeated domain in type 4 procollagen Aa_trans PF01490.16 MSTRG.135222.1_2 - 2e-16 59.6 7.0 2.4e-16 59.3 7.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4199 PF13858.4 MSTRG.135222.1_2 - 0.35 11.1 7.1 0.56 10.5 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Sirohm_synth_C PF14823.4 MSTRG.82218.1_1 - 0.057 12.9 6.6 0.093 12.2 6.6 1.3 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal R3H PF01424.20 MSTRG.82218.1_3 - 1.1e-13 50.8 0.0 2.7e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 R3H domain DUF3043 PF11241.6 MSTRG.82218.1_3 - 0.26 11.2 1.4 0.44 10.4 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) zf-C2H2 PF00096.24 MSTRG.26366.1_3 - 1.5 9.3 0.0 1.5 9.3 0.0 3.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF1992 PF09350.8 MSTRG.3900.1_3 - 0.098 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) Propeptide_C25 PF08126.9 MSTRG.83203.1_2 - 0.0014 17.7 7.6 0.0062 15.5 1.7 2.4 1 1 0 2 2 2 2 Propeptide_C25 DASH_Dad4 PF08650.8 MSTRG.83203.1_2 - 0.32 10.9 12.4 36 4.3 0.1 5.6 3 2 3 6 6 6 0 DASH complex subunit Dad4 Agenet PF05641.10 MSTRG.83203.1_2 - 0.45 10.9 4.0 46 4.5 0.1 3.9 1 1 3 4 4 4 0 Agenet domain Opiods_neuropep PF01160.16 MSTRG.83203.1_3 - 1.8 8.6 16.5 2.3 8.3 1.4 4.4 1 1 4 5 5 5 0 Vertebrate endogenous opioids neuropeptide fn3 PF00041.19 MSTRG.104603.2_1 - 8.9e-20 70.7 2.3 4.8e-13 49.1 0.3 2.0 2 0 0 2 2 2 2 Fibronectin type III domain fn3_2 PF16893.3 MSTRG.104603.2_1 - 0.013 15.5 1.8 0.56 10.3 0.1 2.4 2 1 0 2 2 2 0 Fibronectin type III domain DUF2369 PF10179.7 MSTRG.104603.2_1 - 0.057 13.8 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Alpha-amylase PF00128.22 MSTRG.140270.1_2 - 0.00024 20.7 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Sprouty PF05210.11 MSTRG.29525.1_2 - 0.067 13.5 1.1 0.079 13.3 1.1 1.2 1 0 0 1 1 1 0 Sprouty protein (Spry) Hormone_4 PF00220.15 MSTRG.25902.1_3 - 0.21 11.5 0.7 0.21 11.5 0.7 2.7 3 0 0 3 3 3 0 Neurohypophysial hormones, N-terminal Domain Cyt-b5 PF00173.26 MSTRG.108589.1_2 - 0.0035 17.3 0.0 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NapE PF06796.9 MSTRG.43588.1_1 - 7.2 6.1 7.3 29 4.1 0.1 2.2 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DDE_3 PF13358.4 MSTRG.97641.1_3 - 7e-06 25.7 0.0 7.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Herpes_UL49_2 PF04823.10 MSTRG.97609.1_3 - 0.099 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein NCD3G PF07562.12 MSTRG.24063.1_3 - 3 7.8 9.0 8.2 6.4 0.9 2.6 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Pkinase PF00069.23 MSTRG.120033.2_3 - 6.1e-09 35.5 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.120033.2_3 - 0.00011 21.4 0.3 0.00017 20.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2119 PF09892.7 MSTRG.64639.1_1 - 0.19 10.9 0.1 0.25 10.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) MR_MLE_C PF13378.4 MSTRG.130398.1_3 - 8.1e-20 71.3 0.1 9.9e-20 71.0 0.1 1.0 1 0 0 1 1 1 1 Enolase C-terminal domain-like Flavi_NS1 PF00948.19 MSTRG.50831.1_2 - 0.092 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Arf PF00025.19 MSTRG.45889.2_2 - 1.6e-77 258.8 0.1 2e-77 258.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.11 MSTRG.45889.2_2 - 1.9e-13 50.5 0.0 2.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.8 MSTRG.45889.2_2 - 3.1e-13 49.4 0.0 4.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.20 MSTRG.45889.2_2 - 1e-11 44.6 0.0 1.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.18 MSTRG.45889.2_2 - 9.6e-11 41.3 1.0 3.6e-07 29.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.10 MSTRG.45889.2_2 - 6.4e-10 38.6 0.0 9.1e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 MSTRG.45889.2_2 - 9.7e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 MSTRG.45889.2_2 - 0.013 14.7 0.3 0.043 13.0 0.1 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Zfx_Zfy_act PF04704.11 MSTRG.100774.1_2 - 5.4e-05 22.3 7.5 6.6e-05 22.1 7.5 1.1 1 0 0 1 1 1 1 Zfx / Zfy transcription activation region zf-LYAR PF08790.9 MSTRG.14179.1_3 - 9.9e-17 60.4 4.1 3.4e-15 55.5 1.3 2.6 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger DUF4780 PF16012.3 MSTRG.14179.1_3 - 0.038 13.3 0.3 0.063 12.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) zf-H2C2_2 PF13465.4 MSTRG.104888.1_1 - 3.5e-44 147.2 32.1 4.4e-09 36.2 1.9 5.6 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.104888.1_1 - 8.9e-30 101.3 42.5 7.2e-07 29.2 2.6 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.104888.1_1 - 2.7e-20 71.1 38.5 8.5e-05 22.9 1.9 6.0 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.104888.1_1 - 1.8e-07 30.8 41.8 0.00075 19.3 1.6 6.4 6 1 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.104888.1_1 - 2.6e-06 27.4 29.9 0.032 14.4 1.2 6.0 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding C1_1 PF00130.20 MSTRG.104888.1_1 - 3.7e-06 26.6 18.7 0.34 10.7 2.9 4.9 1 1 3 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.8 MSTRG.104888.1_1 - 2.9e-05 24.0 20.9 0.016 15.2 4.3 4.3 1 1 4 5 5 5 5 Zinc ribbon domain zf-LYAR PF08790.9 MSTRG.104888.1_1 - 0.00061 19.5 11.6 0.019 14.7 0.8 5.6 6 0 0 6 6 6 3 LYAR-type C2HC zinc finger zinc_ribbon_15 PF17032.3 MSTRG.104888.1_1 - 0.00065 20.3 17.6 0.06 14.0 3.2 3.0 1 1 3 4 4 4 4 zinc-ribbon family zf-C2HE PF16278.3 MSTRG.104888.1_1 - 0.0018 18.6 26.0 0.2 12.0 4.0 4.5 1 1 4 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.5 MSTRG.104888.1_1 - 0.0047 16.8 21.9 1.5 8.7 4.8 3.2 1 1 1 2 2 2 1 Double zinc ribbon SprT-like PF10263.7 MSTRG.104888.1_1 - 0.0049 16.6 21.6 0.009 15.7 5.3 2.7 1 1 2 3 3 3 2 SprT-like family C1_4 PF07975.10 MSTRG.104888.1_1 - 0.005 16.9 21.7 0.41 10.8 3.7 3.8 2 1 2 4 4 4 1 TFIIH C1-like domain DUF3268 PF11672.6 MSTRG.104888.1_1 - 0.0055 16.9 13.6 0.38 11.0 1.2 3.1 1 1 4 5 5 5 4 zinc-finger-containing domain BolA PF01722.16 MSTRG.104888.1_1 - 0.014 15.5 5.1 0.037 14.2 0.1 2.7 2 1 1 3 3 3 0 BolA-like protein FYDLN_acid PF09538.8 MSTRG.104888.1_1 - 0.016 15.8 6.9 4 8.0 0.3 3.7 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) HypA PF01155.17 MSTRG.104888.1_1 - 0.018 14.9 13.8 4.1 7.3 4.1 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-trcl PF13451.4 MSTRG.104888.1_1 - 0.029 14.1 16.1 4.3 7.2 0.1 5.1 5 0 0 5 5 5 0 Probable zinc-ribbon domain C1_2 PF03107.14 MSTRG.104888.1_1 - 0.032 14.4 22.5 9.7 6.5 0.2 5.0 2 1 0 3 3 3 0 C1 domain zf-HIT PF04438.14 MSTRG.104888.1_1 - 0.037 13.8 17.7 4.3 7.2 0.3 5.1 5 0 0 5 5 5 0 HIT zinc finger DUF2256 PF10013.7 MSTRG.104888.1_1 - 0.049 13.6 9.1 6 7.0 0.1 4.5 5 0 0 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc-ribbons_6 PF07191.10 MSTRG.104888.1_1 - 0.052 13.4 21.7 3.2 7.7 0.6 4.8 1 1 3 4 4 4 0 zinc-ribbons zf-Paramyx-P PF13008.5 MSTRG.104888.1_1 - 0.055 12.8 12.5 21 4.5 0.1 5.0 5 0 0 5 5 5 0 Zinc-binding domain of Paramyxoviridae V protein BDHCT_assoc PF16204.3 MSTRG.104888.1_1 - 0.056 13.0 3.0 0.11 12.0 2.5 1.7 1 1 1 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein XPA_N PF01286.16 MSTRG.104888.1_1 - 0.081 12.8 23.8 3.7 7.6 0.4 5.8 6 0 0 6 6 6 0 XPA protein N-terminal zf-AN1 PF01428.14 MSTRG.104888.1_1 - 0.086 12.9 24.0 4.8 7.3 0.9 5.2 3 1 1 5 5 5 0 AN1-like Zinc finger Evr1_Alr PF04777.11 MSTRG.104888.1_1 - 0.12 12.8 17.0 4.9 7.6 0.3 4.4 1 1 2 3 3 3 0 Erv1 / Alr family ADK_lid PF05191.12 MSTRG.104888.1_1 - 0.13 12.2 13.4 0.61 10.0 1.1 3.7 2 2 2 4 4 4 0 Adenylate kinase, active site lid K-box PF01486.15 MSTRG.104888.1_1 - 0.26 11.4 2.0 44 4.2 0.0 3.8 2 2 2 5 5 4 0 K-box region zf-C2H2_2 PF12756.5 MSTRG.104888.1_1 - 0.3 11.3 19.5 1.2 9.4 1.0 3.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.5 MSTRG.104888.1_1 - 0.55 10.6 42.3 0.21 11.9 2.3 5.7 6 0 0 6 6 5 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 MSTRG.104888.1_1 - 0.6 9.8 22.0 0.28 10.8 2.1 4.5 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-RING_7 PF02591.13 MSTRG.104888.1_1 - 0.84 9.8 14.3 16 5.6 0.1 4.4 5 0 0 5 5 4 0 C4-type zinc ribbon domain PHD PF00628.27 MSTRG.104888.1_1 - 1.9 8.3 22.9 11 5.8 4.1 4.0 1 1 4 5 5 5 0 PHD-finger zf-BED PF02892.13 MSTRG.104888.1_1 - 2.1 8.4 18.3 3.4 7.7 2.4 4.3 1 1 3 4 4 4 0 BED zinc finger zf-HYPF PF07503.10 MSTRG.104888.1_1 - 5 6.9 14.4 11 5.8 0.2 4.6 5 0 0 5 5 5 0 HypF finger Zn_ribbon_recom PF13408.4 MSTRG.104888.1_1 - 5.8 7.4 16.7 9.6 6.7 1.8 3.8 1 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-C2HC_2 PF13913.4 MSTRG.104888.1_1 - 6.4 6.7 12.2 13 5.7 0.2 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type LIM PF00412.20 MSTRG.104888.1_1 - 9.8 6.4 20.1 5.8 7.1 0.5 4.2 1 1 3 4 4 4 0 LIM domain zf-H2C2_2 PF13465.4 MSTRG.104888.1_2 - 0.055 13.8 5.9 9.9 6.7 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger double domain DUF1891 PF09004.8 MSTRG.72824.1_2 - 9.1e-07 28.2 0.1 2e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) HTH_psq PF05225.14 MSTRG.29559.1_1 - 0.033 13.8 0.1 0.072 12.7 0.0 1.5 2 0 0 2 2 2 0 helix-turn-helix, Psq domain DDE_3 PF13358.4 MSTRG.29559.1_3 - 3.6e-07 29.9 1.1 7.2e-07 28.9 1.1 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease UQ_con PF00179.24 MSTRG.80212.2_2 - 0.00047 19.7 0.1 0.00091 18.8 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme CHASE9 PF17153.2 MSTRG.80212.2_2 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular RVT_1 PF00078.25 MSTRG.50099.1_3 - 3.1e-07 30.0 0.0 5e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_38 PF13936.4 MSTRG.20798.1_1 - 7.9e-06 25.4 0.1 1.2e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.20798.1_1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.4 MSTRG.20798.1_1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S13_N PF08069.10 MSTRG.20798.1_1 - 0.014 15.3 0.3 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 Ribosomal S13/S15 N-terminal domain HTH_Tnp_ISL3 PF13542.4 MSTRG.20798.1_1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF4269 PF14091.4 MSTRG.20798.1_1 - 0.11 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Mur_ligase_M PF08245.10 MSTRG.143763.1_2 - 2.7e-05 24.1 0.0 8.2e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain ABC_trans_aux PF03886.11 MSTRG.29730.1_1 - 0.02 14.3 7.2 0.36 10.2 0.9 2.1 1 1 1 2 2 2 0 ABC-type transport auxiliary lipoprotein component YojJ PF10372.7 MSTRG.29730.1_1 - 0.087 12.8 9.2 4.7 7.3 0.8 3.2 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus MRP_L53 PF10780.7 MSTRG.29730.1_1 - 0.16 12.0 2.1 23 5.1 0.3 2.9 1 1 2 3 3 3 0 39S ribosomal protein L53/MRP-L53 DUF3663 PF12404.6 MSTRG.29730.1_1 - 0.71 9.8 4.0 6.3 6.8 0.2 2.2 1 1 0 2 2 2 0 Peptidase T3SS_needle_E PF08988.8 MSTRG.29730.1_1 - 1.5 9.0 11.5 5.3 7.2 1.9 2.6 1 1 1 2 2 2 0 Type III secretion system, cytoplasmic E component of needle TFIIE_beta PF02186.13 MSTRG.29730.1_1 - 2.2 8.5 10.6 80 3.5 3.3 4.0 1 1 2 3 3 3 0 TFIIE beta subunit core domain Pentapeptide_2 PF01469.16 MSTRG.29730.1_3 - 0.24 11.2 3.9 3.4 7.5 0.6 2.6 1 1 2 3 3 3 0 Pentapeptide repeats (8 copies) Annexin PF00191.18 MSTRG.29730.1_3 - 1.4 8.9 12.8 10 6.2 1.0 3.8 1 1 4 5 5 5 0 Annexin Exo_endo_phos PF03372.21 MSTRG.26758.1_2 - 0.089 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PFK PF00365.18 MSTRG.1149.2_1 - 6.4e-138 458.6 8.8 2.6e-111 371.4 3.1 2.2 2 0 0 2 2 2 2 Phosphofructokinase Carboxyl_trans PF01039.20 MSTRG.70360.1_2 - 5.1e-59 200.1 0.0 6e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain DNA_pol_B_2 PF03175.11 MSTRG.70360.1_2 - 0.085 11.6 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Anoctamin PF04547.10 MSTRG.122456.1_3 - 2.8e-08 32.8 0.0 3.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel CUB PF00431.18 MSTRG.44220.1_3 - 4.2e-05 23.7 0.0 4.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 CUB domain Caldesmon PF02029.13 MSTRG.84192.2_1 - 4.4e-48 164.1 63.2 4.4e-48 164.1 63.2 2.0 1 1 1 2 2 2 1 Caldesmon Glyco_hydro_38 PF01074.20 MSTRG.31958.1_1 - 6.1e-36 124.1 0.0 6.7e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain MTHFR_C PF12225.6 MSTRG.86985.1_3 - 0.017 14.7 1.6 0.022 14.3 1.6 1.1 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal Med26 PF08711.9 MSTRG.3254.1_1 - 5.9e-15 54.9 2.2 5.9e-15 54.9 2.2 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF3349 PF11829.6 MSTRG.3254.1_1 - 0.0042 17.7 0.3 0.13 12.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) Diphthami_syn_2 PF01902.15 MSTRG.3254.1_1 - 0.031 13.6 1.7 0.14 11.5 0.4 1.9 1 1 1 2 2 2 0 Diphthamide synthase Snf7 PF03357.19 MSTRG.3254.1_1 - 0.17 11.3 9.3 0.27 10.7 9.3 1.3 1 0 0 1 1 1 0 Snf7 BAR_3 PF16746.3 MSTRG.60282.2_2 - 3.4e-11 43.2 0.1 3.8e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 BAR domain of APPL family KRTAP PF11759.6 MSTRG.143559.1_1 - 0.06 13.8 3.2 0.072 13.5 3.2 1.1 1 0 0 1 1 1 0 Keratin-associated matrix BetaGal_dom4_5 PF13364.4 MSTRG.34618.1_2 - 4e-07 30.5 0.0 6.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain DUF1908 PF08926.9 MSTRG.26421.1_3 - 6.9e-16 58.0 2.6 8.3e-16 57.8 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1908) KAR9 PF08580.8 MSTRG.26421.1_3 - 6.2 5.1 5.3 6.9 4.9 5.3 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Helicase_C PF00271.29 MSTRG.4128.1_1 - 7.4e-16 58.4 0.0 8.2e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Rota_NS6 PF04866.10 MSTRG.46332.1_2 - 0.2 11.8 2.3 9.6 6.4 0.5 2.2 2 0 0 2 2 2 0 Rotavirus non-structural protein 6 RVT_1 PF00078.25 MSTRG.17026.1_2 - 4.4e-05 23.0 0.0 4.8e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.20 MSTRG.134918.1_1 - 1.3e-10 40.8 0.0 1.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.10 MSTRG.134918.1_1 - 0.00067 19.8 22.3 0.00094 19.3 22.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Spem1 PF15670.3 MSTRG.134918.1_1 - 0.067 12.6 6.2 0.082 12.3 6.2 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 RSRP PF17069.3 MSTRG.134918.1_1 - 0.77 9.1 47.4 1 8.7 47.4 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Apt1 PF10351.7 MSTRG.134918.1_1 - 0.96 8.1 13.1 1.1 7.9 13.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.11 MSTRG.134918.1_1 - 1.2 7.7 10.6 1.5 7.4 10.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.15 MSTRG.134918.1_1 - 2 7.0 8.8 2.3 6.7 8.8 1.1 1 0 0 1 1 1 0 Presenilin ORC6 PF05460.11 MSTRG.134918.1_1 - 2.6 7.1 13.3 3.2 6.8 13.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Bax1-I PF01027.18 MSTRG.85742.1_3 - 2.8e-18 66.4 8.2 5.3e-18 65.5 8.2 1.4 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Ldl_recept_b PF00058.15 MSTRG.85013.1_1 - 2.2e-11 43.9 0.1 9.3e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Low-density lipoprotein receptor repeat class B DUF4907 PF16250.3 MSTRG.76122.1_2 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) RVT_1 PF00078.25 MSTRG.42694.1_1 - 1.8e-18 66.7 0.0 4.2e-18 65.5 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NapB PF03892.12 MSTRG.86838.1_3 - 0.14 12.0 1.8 0.3 11.0 1.8 1.4 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Axin_b-cat_bind PF08833.8 MSTRG.135321.1_3 - 0.046 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Axin beta-catenin binding domain Mg_trans_NIPA PF05653.12 MSTRG.67361.1_1 - 1.3e-101 339.5 19.1 1.5e-101 339.3 19.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.18 MSTRG.67361.1_1 - 1.3e-06 28.5 9.1 1.3e-06 28.5 9.1 3.3 2 1 0 2 2 2 1 EamA-like transporter family Cullin_Nedd8 PF10557.7 MSTRG.22584.1_2 - 1.6e-19 69.6 7.1 2e-19 69.2 7.1 1.2 1 0 0 1 1 1 1 Cullin protein neddylation domain Stork_head PF10264.7 MSTRG.22584.1_2 - 0.0028 17.7 0.7 0.0037 17.2 0.7 1.2 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain DUF4757 PF15949.3 MSTRG.71124.1_2 - 3.6e-12 47.0 0.1 5e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4757) Band_3_cyto PF07565.11 MSTRG.41079.1_3 - 3.4e-07 30.2 0.0 4.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Adeno_E3A PF05248.10 MSTRG.81678.1_3 - 0.0014 18.5 1.2 0.0028 17.5 1.2 1.5 1 0 0 1 1 1 1 Adenovirus E3A A_deamin PF02137.16 MSTRG.22361.1_2 - 4.9e-12 45.8 0.0 4.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain TAF8_C PF10406.7 MSTRG.100831.1_3 - 1.2e-22 80.0 1.5 2.4e-22 79.1 1.5 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term FlpD PF02662.14 MSTRG.95068.1_1 - 0.1 12.5 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Ndr PF03096.12 MSTRG.143490.1_3 - 7e-118 392.3 0.0 8.7e-118 392.0 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.18 MSTRG.143490.1_3 - 0.0015 18.1 0.0 0.049 13.1 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 MSTRG.143490.1_3 - 0.0025 18.3 0.0 0.0037 17.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1031 PF06275.9 MSTRG.135540.1_1 - 0.047 13.8 0.4 0.074 13.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Anoctamin PF04547.10 MSTRG.45403.1_1 - 2.8e-17 62.5 0.6 3.4e-17 62.2 0.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel PufQ PF05398.9 MSTRG.45403.1_1 - 0.048 13.7 0.3 0.064 13.3 0.3 1.2 1 0 0 1 1 1 0 PufQ cytochrome subunit DUF829 PF05705.12 MSTRG.77967.1_2 - 0.12 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Med12-LCEWAV PF12145.6 MSTRG.72079.1_1 - 3.1e-44 151.5 1.2 5.4e-44 150.7 1.2 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain DUF4653 PF15546.4 MSTRG.72079.1_3 - 0.063 12.8 0.2 0.082 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Sec6 PF06046.11 MSTRG.5473.1_3 - 1e-21 76.8 0.1 1.1e-21 76.7 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 TPR_2 PF07719.15 MSTRG.35173.1_3 - 3.3e-07 29.8 1.3 0.005 16.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.4 MSTRG.35173.1_3 - 0.00012 21.5 1.9 0.099 12.2 0.1 2.2 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.4 MSTRG.35173.1_3 - 0.00025 21.1 0.5 0.0015 18.6 0.1 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.4 MSTRG.35173.1_3 - 0.00029 20.7 2.3 0.00073 19.4 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.4 MSTRG.35173.1_3 - 0.0003 21.1 1.0 0.003 17.9 1.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.4 MSTRG.35173.1_3 - 0.0004 20.5 0.3 0.032 14.5 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.26 MSTRG.35173.1_3 - 0.00068 19.2 4.0 0.005 16.5 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.4 MSTRG.35173.1_3 - 0.0012 18.6 0.1 0.12 12.3 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.4 MSTRG.35173.1_3 - 0.0047 17.5 1.1 1.2 9.8 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat COPI_C PF06957.9 MSTRG.35173.1_3 - 0.075 11.7 0.4 0.93 8.1 0.1 1.9 1 1 1 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Ig_3 PF13927.4 MSTRG.98308.1_3 - 4.6e-08 33.4 0.2 1.1e-07 32.2 0.2 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 MSTRG.98308.1_3 - 7e-08 32.3 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.4 MSTRG.98308.1_3 - 1.3e-06 28.5 0.1 3.1e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.98308.1_3 - 0.028 14.4 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.15 MSTRG.98308.1_3 - 0.14 12.2 1.2 0.2 11.7 0.2 1.7 2 0 0 2 2 2 0 Immunoglobulin V-set domain DDE_3 PF13358.4 MSTRG.4195.1_1 - 4.4e-10 39.4 0.1 5e-10 39.2 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Filamin PF00630.17 MSTRG.2920.2_2 - 1.2e-22 80.5 1.0 4.8e-17 62.5 0.1 2.2 2 0 0 2 2 2 2 Filamin/ABP280 repeat DUF5060 PF16586.3 MSTRG.2920.2_2 - 0.12 12.6 0.0 2.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) Gal-bind_lectin PF00337.20 MSTRG.134236.1_1 - 3e-26 91.4 0.1 3.8e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Pkinase_Tyr PF07714.15 MSTRG.134236.1_2 - 0.00011 21.5 0.0 0.00014 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Oxysterol_BP PF01237.16 MSTRG.123623.1_1 - 3.5e-27 95.1 0.1 4.5e-27 94.7 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein RVT_1 PF00078.25 MSTRG.66294.1_3 - 0.00088 18.7 0.1 0.0012 18.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran PF00005.25 MSTRG.142824.2_2 - 3.3e-07 30.8 0.4 5.4e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.4 MSTRG.142824.2_2 - 0.0013 18.5 0.5 0.015 15.0 0.2 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.4 MSTRG.142824.2_2 - 0.095 12.2 0.2 0.13 11.7 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.10 MSTRG.142824.2_2 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 NACHT domain RVT_1 PF00078.25 MSTRG.104822.1_1 - 8.9e-06 25.2 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transket_pyr PF02779.22 MSTRG.33088.1_1 - 1.2e-20 73.8 0.0 1.4e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain MT0933_antitox PF14013.4 MSTRG.28884.1_3 - 0.13 12.4 13.1 2.7 8.2 13.1 2.5 1 1 0 1 1 1 0 MT0933-like antitoxin protein InaF-motif PF15018.4 MSTRG.100127.1_2 - 5.1 6.9 6.0 29 4.5 0.1 2.8 3 0 0 3 3 3 0 TRP-interacting helix Lebercilin PF15619.4 MSTRG.83039.1_2 - 0.00088 18.8 31.0 0.00088 18.8 31.0 4.8 1 1 5 6 6 6 1 Ciliary protein causing Leber congenital amaurosis disease LigT_PEase PF02834.14 MSTRG.83039.1_2 - 0.0054 16.8 0.8 0.038 14.0 0.1 2.9 2 1 1 3 3 3 1 LigT like Phosphoesterase RusA PF05866.9 MSTRG.83039.1_2 - 0.069 13.6 0.3 0.27 11.6 0.1 1.9 1 1 0 1 1 1 0 Endodeoxyribonuclease RusA ADIP PF11559.6 MSTRG.83039.1_2 - 0.21 11.5 65.2 0.072 13.0 4.3 6.0 1 1 4 6 6 6 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.10 MSTRG.83039.1_2 - 0.42 9.8 15.4 0.7 9.1 0.2 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Fez1 PF06818.13 MSTRG.83039.1_2 - 1.8 8.9 68.9 1.4 9.2 24.4 4.3 1 1 3 4 4 4 0 Fez1 Spc7 PF08317.9 MSTRG.83039.1_2 - 3.9 6.1 69.5 0.18 10.6 11.6 4.2 1 1 4 5 5 5 0 Spc7 kinetochore protein Pilt PF15453.4 MSTRG.14828.1_2 - 0.13 11.5 0.4 0.16 11.2 0.4 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions FH2 PF02181.21 MSTRG.73521.1_3 - 9.5e-19 67.6 0.8 1e-18 67.5 0.8 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DDE_3 PF13358.4 MSTRG.92420.1_3 - 0.00077 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Collagen PF01391.16 MSTRG.60989.1_2 - 2.5e-12 46.2 31.2 2.9e-08 33.2 20.1 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Exo_endo_phos_2 PF14529.4 MSTRG.142500.1_3 - 0.028 14.1 0.3 0.038 13.7 0.3 1.4 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Got1 PF04178.10 MSTRG.67085.1_2 - 1.2e-16 61.0 7.2 1.7e-16 60.5 7.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3185 PF11381.6 MSTRG.67085.1_2 - 0.38 10.7 7.3 5.4 7.0 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) RVT_1 PF00078.25 MSTRG.14898.1_1 - 6.2e-08 32.3 0.0 1.4e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-primase PF09329.9 MSTRG.100966.1_3 - 0.11 12.2 2.6 0.17 11.5 2.6 1.4 1 0 0 1 1 1 0 Primase zinc finger Tat PF00539.16 MSTRG.100966.1_3 - 0.63 10.1 4.7 1.1 9.3 4.7 1.5 1 1 0 1 1 1 0 Transactivating regulatory protein (Tat) CI-B14_5a PF07347.10 MSTRG.21994.1_2 - 5.3e-31 106.2 0.3 6.5e-31 106.0 0.3 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Atrophin-1 PF03154.13 MSTRG.135326.1_3 - 0.18 9.9 7.4 0.2 9.8 7.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family FCH PF00611.21 MSTRG.68416.2_1 - 0.00031 20.8 0.0 0.00069 19.7 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Snapin_Pallidin PF14712.4 MSTRG.68416.2_1 - 0.083 13.2 4.2 0.12 12.6 4.2 1.3 1 0 0 1 1 1 0 Snapin/Pallidin FlaC_arch PF05377.9 MSTRG.68416.2_1 - 0.086 13.1 1.5 8.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-C6H2 PF15801.3 MSTRG.30366.1_1 - 1.2 9.4 0.1 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding ETRAMP PF09716.8 MSTRG.133608.1_3 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RVT_1 PF00078.25 MSTRG.138756.1_3 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.23 MSTRG.134045.1_1 - 1.3e-40 139.4 0.1 2.4e-40 138.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.134045.1_1 - 1.2e-20 73.8 0.1 2e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 MSTRG.134045.1_1 - 0.00014 21.2 2.1 0.0003 20.1 2.1 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.12 MSTRG.134045.1_1 - 0.00042 19.6 0.0 0.0011 18.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 MSTRG.134045.1_1 - 0.00053 19.9 0.1 0.02 14.7 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.9 MSTRG.134045.1_1 - 0.041 12.8 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MEKHLA PF08670.9 MSTRG.134045.1_1 - 0.29 10.9 3.5 0.11 12.2 0.6 1.7 2 0 0 2 2 2 0 MEKHLA domain WD40 PF00400.30 MSTRG.34319.2_2 - 0.0031 18.2 3.6 28 5.7 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Dynein_IC2 PF11540.6 MSTRG.34319.2_3 - 1.2e-14 53.8 0.3 2.1e-14 53.0 0.3 1.4 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.30 MSTRG.34319.2_3 - 8.2e-06 26.3 4.2 0.044 14.5 0.9 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.34319.2_3 - 0.0028 17.8 0.0 0.01 16.0 0.0 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Stm1_N PF09598.8 MSTRG.34319.2_3 - 1.1 10.1 5.1 2.9 8.7 5.1 1.7 1 0 0 1 1 1 0 Stm1 HAND PF09110.9 MSTRG.34319.2_3 - 1.5 9.5 8.6 2.7 8.7 8.6 1.3 1 0 0 1 1 1 0 HAND Ank_2 PF12796.5 MSTRG.66480.1_2 - 3e-36 123.7 13.0 2.9e-13 50.1 0.4 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.4 MSTRG.66480.1_2 - 4.5e-24 84.4 3.9 1e-08 35.4 0.1 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.28 MSTRG.66480.1_2 - 1.8e-16 59.6 7.8 0.0005 20.3 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.4 MSTRG.66480.1_2 - 3.1e-14 52.7 8.6 1.5e-07 31.4 0.2 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.4 MSTRG.66480.1_2 - 1.9e-13 49.1 0.3 0.0015 18.7 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat RVT_1 PF00078.25 MSTRG.85180.1_1 - 1.5e-13 50.6 0.1 1.7e-13 50.5 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Get5_bdg PF16843.3 MSTRG.85180.1_1 - 0.025 13.9 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein Tropomyosin PF00261.18 MSTRG.67582.1_2 - 2e-88 295.6 60.1 2.5e-88 295.3 60.1 1.1 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.5 MSTRG.67582.1_2 - 7.5e-23 81.1 59.7 4.2e-20 72.2 32.9 3.0 1 1 2 3 3 3 3 Tropomyosin like DUF3450 PF11932.6 MSTRG.67582.1_2 - 0.0009 18.5 7.6 0.0009 18.5 7.6 2.9 1 1 2 3 3 2 1 Protein of unknown function (DUF3450) Laminin_II PF06009.10 MSTRG.67582.1_2 - 0.00092 19.1 32.4 0.0039 17.1 6.2 3.7 1 1 2 3 3 3 2 Laminin Domain II TMF_DNA_bd PF12329.6 MSTRG.67582.1_2 - 0.0098 15.7 11.7 0.0098 15.7 11.7 4.4 2 1 1 4 4 4 2 TATA element modulatory factor 1 DNA binding DUF745 PF05335.11 MSTRG.67582.1_2 - 0.11 12.1 43.7 0.88 9.2 6.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Lebercilin PF15619.4 MSTRG.67582.1_2 - 0.11 12.0 50.9 0.06 12.8 19.4 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CALCOCO1 PF07888.9 MSTRG.67582.1_2 - 0.25 9.7 44.6 0.43 9.0 44.6 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DASH_Duo1 PF08651.8 MSTRG.67582.1_2 - 0.32 10.7 10.9 2.6 7.8 0.2 3.5 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF724 PF05266.12 MSTRG.67582.1_2 - 0.37 10.5 44.7 0.22 11.2 21.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Fib_alpha PF08702.8 MSTRG.67582.1_2 - 0.44 10.6 25.8 1.1 9.3 4.8 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FH2 PF02181.21 MSTRG.67582.1_2 - 0.58 9.1 30.0 0.015 14.3 10.0 2.7 1 1 2 3 3 3 0 Formin Homology 2 Domain DUF1664 PF07889.10 MSTRG.67582.1_2 - 1 9.2 26.6 0.99 9.3 8.7 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) MscS_porin PF12795.5 MSTRG.67582.1_2 - 2.8 7.3 44.3 3.3 7.1 10.5 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.10 MSTRG.67582.1_2 - 3 7.7 12.6 8.1 6.3 1.8 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.10 MSTRG.67582.1_2 - 4.7 6.4 8.8 2.6 7.2 0.8 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein RPW8 PF05659.9 MSTRG.67582.1_2 - 8.1 6.0 19.9 0.066 12.8 2.3 3.6 3 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Glyco_transf_7C PF02709.12 MSTRG.21736.1_2 - 2 8.0 10.9 4.1 7.0 1.7 2.3 1 1 1 2 2 2 0 N-terminal domain of galactosyltransferase CCG PF02754.14 MSTRG.21736.1_3 - 4.7 7.4 10.1 2.2 8.4 0.3 2.6 1 1 1 2 2 2 0 Cysteine-rich domain SH PF01445.15 MSTRG.120321.1_1 - 0.12 12.2 2.5 0.17 11.7 2.5 1.2 1 0 0 1 1 1 0 Viral small hydrophobic protein RVT_1 PF00078.25 MSTRG.120321.1_3 - 0.0011 18.4 0.0 0.0012 18.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med2 PF11214.6 MSTRG.120321.1_3 - 0.14 12.2 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF3915 PF13054.4 MSTRG.122912.1_1 - 2.8 7.8 8.7 3.7 7.4 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 MSTRG.122912.1_2 - 1.7 6.7 16.8 2 6.5 16.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 MSTRG.122912.1_2 - 3.8 7.4 12.3 5.2 6.9 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.56002.1_2 - 1.2e-07 31.7 0.6 1.2e-07 31.7 0.6 1.9 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.4 MSTRG.56002.1_2 - 2.5e-05 23.8 0.1 5.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.4 MSTRG.56002.1_2 - 6.3e-05 22.5 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.4 MSTRG.56002.1_2 - 0.026 13.8 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 PAX PF00292.16 MSTRG.56002.1_2 - 0.037 13.8 0.1 0.057 13.2 0.1 1.4 1 1 0 1 1 1 0 'Paired box' domain HTH_28 PF13518.4 MSTRG.56002.1_2 - 0.04 13.9 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S13_N PF08069.10 MSTRG.56002.1_2 - 0.044 13.7 0.5 0.45 10.5 0.1 2.3 1 1 1 2 2 2 0 Ribosomal S13/S15 N-terminal domain DUF4458 PF14660.4 MSTRG.140812.1_1 - 0.039 14.0 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) Ldl_recept_b PF00058.15 MSTRG.105128.1_2 - 7.4e-13 48.6 0.2 1.3e-05 25.4 0.0 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.4 MSTRG.105128.1_2 - 4.2e-06 26.8 8.9 7e-06 26.1 8.9 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site HCMVantigenic_N PF12154.6 MSTRG.82830.1_2 - 0.0093 15.9 0.6 4.3 7.4 0.1 3.4 2 1 2 4 4 4 2 Glycoprotein B N-terminal antigenic domain of HCMV UPA PF17217.1 MSTRG.82830.1_2 - 0.013 15.4 1.1 2.5 8.0 0.1 2.1 2 0 0 2 2 2 0 UPA domain ThrE_2 PF12821.5 MSTRG.102896.1_1 - 0.18 11.8 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE SOCS_box PF07525.14 MSTRG.54882.1_1 - 9.1e-12 45.0 0.9 2e-11 43.9 0.9 1.6 1 0 0 1 1 1 1 SOCS box SH2 PF00017.22 MSTRG.54882.1_1 - 5.5e-09 35.8 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain AAA_3 PF07726.9 MSTRG.107461.1_1 - 0.013 15.2 0.3 0.2 11.4 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) MIG-14_Wnt-bd PF06664.10 MSTRG.39812.1_3 - 1e-16 60.9 4.3 1.3e-16 60.6 4.3 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion RRM_1 PF00076.20 MSTRG.19447.1_3 - 6.1e-08 32.2 0.0 8.1e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.90986.1_1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Transposase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.90986.1_2 - 4.9e-12 45.8 1.0 6e-12 45.5 1.0 1.1 1 0 0 1 1 1 1 Transposase DUF4725 PF15854.3 MSTRG.111339.1_2 - 0.0019 18.3 0.1 0.0019 18.3 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4725) DUF846 PF05832.10 MSTRG.111339.1_2 - 0.015 15.2 0.5 0.023 14.6 0.5 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Ion_trans PF00520.29 MSTRG.61978.1_1 - 8.8e-18 64.3 5.5 9.7e-18 64.1 5.5 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.10 MSTRG.61978.1_1 - 3.7 6.0 10.8 0.13 10.7 3.2 1.9 1 1 1 2 2 2 0 Polycystin cation channel DUF4930 PF16284.3 MSTRG.66876.1_2 - 0.089 12.8 0.0 0.14 12.1 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4930) DDT PF02791.15 MSTRG.65682.1_2 - 0.041 14.1 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 DDT domain BET PF17035.3 MSTRG.143922.1_1 - 4e-15 55.6 0.0 5.2e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation zf-C2H2 PF00096.24 MSTRG.83590.1_2 - 5e-09 36.0 9.6 6.9e-06 26.1 2.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.83590.1_2 - 1.7e-08 34.4 4.7 0.00012 22.3 0.4 3.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.83590.1_2 - 2.1e-07 31.0 10.5 0.0023 18.5 1.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.83590.1_2 - 3.7e-05 23.4 8.2 0.00065 19.4 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.83590.1_2 - 0.0036 17.4 6.4 0.45 10.8 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.9 MSTRG.83590.1_2 - 0.0099 15.5 2.8 1.7 8.4 0.2 2.6 2 1 1 3 3 3 2 GAGA factor zf-met PF12874.5 MSTRG.83590.1_2 - 0.019 15.2 11.4 1.5 9.1 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FYVE PF01363.19 MSTRG.83590.1_2 - 0.17 11.9 9.0 2 8.5 0.5 3.0 2 1 1 3 3 3 0 FYVE zinc finger zf-BED PF02892.13 MSTRG.83590.1_2 - 0.26 11.2 5.4 0.2 11.6 0.9 2.4 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.4 MSTRG.83590.1_3 - 0.0028 17.4 0.3 0.0049 16.6 0.3 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.24 MSTRG.83590.1_3 - 0.0072 16.6 0.7 0.013 15.7 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.83590.1_3 - 0.014 15.7 2.8 0.33 11.3 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.5 MSTRG.83590.1_3 - 0.048 13.9 1.3 0.074 13.3 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.4 MSTRG.83590.1_3 - 0.069 13.9 0.5 0.14 12.9 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1858 PF08984.9 MSTRG.83590.1_3 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) CarbopepD_reg_2 PF13715.4 MSTRG.8234.1_1 - 0.00013 21.7 0.3 0.00025 20.9 0.1 1.5 2 0 0 2 2 2 1 CarboxypepD_reg-like domain RNA_pol_Rpb5_N PF03871.12 MSTRG.14849.1_3 - 4.2e-36 123.2 0.1 5.3e-36 122.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.25760.1_2 - 1.3e-16 60.4 1.1 1.5e-16 60.2 0.3 1.6 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.4 MSTRG.25760.1_2 - 0.12 12.1 0.2 0.78 9.5 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain SAP PF02037.25 MSTRG.96770.1_3 - 6.8e-05 22.4 0.3 0.00012 21.6 0.3 1.5 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.10 MSTRG.96770.1_3 - 0.026 14.3 1.6 0.048 13.5 1.6 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Trypan_PARP PF05887.9 MSTRG.12675.1_1 - 0.0025 17.7 34.1 0.0035 17.2 34.1 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) MM_CoA_mutase PF01642.20 MSTRG.108424.1_3 - 1.2e-101 340.7 0.6 1.4e-101 340.5 0.6 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.17 MSTRG.108424.1_3 - 1.1e-15 57.6 0.0 2.5e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain Collagen PF01391.16 MSTRG.89382.1_2 - 4.4e-49 163.9 236.5 7.9e-08 31.8 34.0 7.1 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) PMG PF05287.10 MSTRG.16051.1_2 - 7.9e-05 22.6 21.0 9.1e-05 22.4 21.0 1.0 1 0 0 1 1 1 1 PMG protein Keratin_B2_2 PF13885.4 MSTRG.16051.1_2 - 9.6e-05 22.1 47.2 1.6e+04 -5.4 47.2 2.6 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Keratin_B2 PF01500.15 MSTRG.16051.1_2 - 8.1 6.3 28.9 1.2e+02 2.5 28.9 2.1 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.75685.1_1 - 4.4e-07 29.9 0.7 4.4e-07 29.9 0.7 2.0 2 1 0 2 2 2 1 Transposase HTH_38 PF13936.4 MSTRG.75685.1_1 - 5.7e-06 25.9 1.4 2.2e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.75685.1_1 - 4.3e-05 23.1 0.2 0.00029 20.4 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.75685.1_1 - 0.005 17.3 0.2 0.03 14.8 0.2 1.9 1 1 1 2 2 2 1 Homeodomain-like domain Ribosomal_S13_N PF08069.10 MSTRG.75685.1_1 - 0.018 14.9 0.4 0.26 11.2 0.1 2.4 1 1 1 2 2 2 0 Ribosomal S13/S15 N-terminal domain PAX PF00292.16 MSTRG.75685.1_1 - 0.036 13.8 0.0 0.053 13.3 0.0 1.4 1 1 0 1 1 1 0 'Paired box' domain MarR_2 PF12802.5 MSTRG.75685.1_1 - 0.046 13.5 0.1 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 MarR family Bot1p PF12298.6 MSTRG.75685.1_1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Arg_repressor PF01316.19 MSTRG.75685.1_1 - 0.054 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_Tnp_ISL3 PF13542.4 MSTRG.75685.1_1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.4 MSTRG.75685.1_1 - 0.089 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4269 PF14091.4 MSTRG.75685.1_1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) Ldh_1_C PF02866.16 MSTRG.67080.1_2 - 3.5e-13 49.7 0.0 4.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain EOS1 PF12326.6 MSTRG.67080.1_3 - 0.037 13.8 0.2 0.056 13.2 0.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF3915 PF13054.4 MSTRG.47899.1_2 - 0.018 14.9 0.8 0.028 14.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FAM27 PF15832.3 MSTRG.47899.1_2 - 0.068 13.6 2.5 0.093 13.2 2.5 1.1 1 0 0 1 1 1 0 FAM27 D and E protein family Atrophin-1 PF03154.13 MSTRG.47899.1_2 - 0.98 7.5 3.9 1.2 7.2 3.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family C1_1 PF00130.20 MSTRG.129382.1_1 - 0.2 11.4 7.4 0.16 11.7 3.9 2.2 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4984 PF16372.3 MSTRG.129382.1_2 - 0.11 12.3 0.0 0.13 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4984) PP2C_C PF07830.11 MSTRG.57686.2_2 - 2.3e-09 37.4 0.0 3.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain DUF3915 PF13054.4 MSTRG.13503.1_1 - 2.8 7.8 8.0 3.5 7.5 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3915 PF13054.4 MSTRG.13503.1_2 - 4.6 7.1 7.2 6 6.7 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 MSTRG.13503.1_3 - 5.4 5.0 9.1 5.2 5.1 9.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family DDE_3 PF13358.4 MSTRG.120363.1_3 - 1.5e-08 34.3 0.5 1.7e-08 34.2 0.5 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Cadherin PF00028.15 MSTRG.61510.1_3 - 1.4e-12 47.7 0.0 1.7e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 Cadherin domain Cadherin_3 PF16184.3 MSTRG.61510.1_3 - 0.016 15.1 0.4 0.024 14.5 0.4 1.3 1 0 0 1 1 1 0 Cadherin-like TPR_12 PF13424.4 MSTRG.118078.1_2 - 0.0043 17.2 0.0 0.0066 16.6 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat RVT_1 PF00078.25 MSTRG.118078.1_3 - 0.0016 17.8 0.1 0.0022 17.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTRF_SDPR PF15237.4 MSTRG.120798.1_3 - 7.8e-18 64.9 15.7 9.9e-16 58.0 15.7 2.3 1 1 0 1 1 1 1 PTRF/SDPR family SsgA PF04686.10 MSTRG.120798.1_3 - 0.0075 16.1 0.8 0.014 15.2 0.8 1.4 1 0 0 1 1 1 1 Streptomyces sporulation and cell division protein, SsgA Mit_KHE1 PF10173.7 MSTRG.120798.1_3 - 0.32 10.9 3.4 0.5 10.3 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF883 PF05957.11 MSTRG.120798.1_3 - 0.89 10.1 4.5 1.8 9.0 4.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) BshC PF10079.7 MSTRG.120798.1_3 - 2.2 6.8 10.4 3.1 6.3 10.4 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF1043 PF06295.10 MSTRG.120798.1_3 - 3.2 7.6 8.3 7 6.5 8.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF342 PF03961.11 MSTRG.120798.1_3 - 4.6 5.6 11.3 0.47 8.9 6.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.13 MSTRG.120798.1_3 - 7 6.0 7.2 11 5.4 7.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YtxH PF12732.5 MSTRG.120798.1_3 - 7.1 7.1 7.3 14 6.2 7.3 1.5 1 0 0 1 1 1 0 YtxH-like protein FERM_C PF09380.8 MSTRG.46176.2_3 - 8.9e-25 86.8 0.0 1.6e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain SAB PF04382.11 MSTRG.46176.2_3 - 2.5e-24 85.0 2.0 2.5e-24 85.0 2.0 2.2 2 0 0 2 2 2 1 SAB domain FERM_M PF00373.16 MSTRG.46176.2_3 - 5.4e-21 75.1 0.6 8.2e-20 71.2 0.0 2.4 2 0 0 2 2 2 1 FERM central domain FA PF08736.9 MSTRG.46176.2_3 - 2.5e-18 65.8 5.3 5.9e-18 64.6 5.3 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.8 MSTRG.46176.2_3 - 4.9e-16 58.3 0.0 1.7e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 FERM N-terminal domain MORN PF02493.18 MSTRG.130183.1_2 - 0.0098 15.6 5.7 5.6 6.9 0.2 3.3 3 0 0 3 3 3 3 MORN repeat DUF5069 PF16798.3 MSTRG.130183.1_2 - 0.061 13.4 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) Leu_leader PF08054.9 MSTRG.143719.1_1 - 0.025 14.0 0.0 5.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Leucine operon leader peptide Leu_leader PF08054.9 MSTRG.143719.1_3 - 0.074 12.5 0.0 16 5.1 0.0 2.3 2 0 0 2 2 2 0 Leucine operon leader peptide rve PF00665.24 MSTRG.102211.1_2 - 9.5e-17 61.2 0.0 1e-16 61.1 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.4 MSTRG.102211.1_2 - 0.03 14.0 0.0 0.036 13.7 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease Mod_r PF07200.11 MSTRG.106566.1_1 - 1.5e-11 44.4 0.0 1.9e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein 7tm_2 PF00002.22 MSTRG.104040.1_1 - 9.4e-06 25.0 0.2 1.5e-05 24.3 0.1 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.22 MSTRG.104040.1_3 - 1.7e-11 43.8 0.0 1.9e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4574 PF15141.4 MSTRG.104040.1_3 - 0.012 15.4 0.4 1.8 8.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4574) zf-B_box PF00643.22 MSTRG.11395.1_1 - 3.7e-10 39.7 5.5 3.7e-10 39.7 5.5 2.2 2 0 0 2 2 2 1 B-box zinc finger DUF812 PF05667.9 MSTRG.11395.1_1 - 0.00067 18.6 2.7 0.00072 18.4 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4201 PF13870.4 MSTRG.11395.1_1 - 0.00099 18.7 3.7 0.0059 16.2 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) MAP65_ASE1 PF03999.10 MSTRG.11395.1_1 - 0.0012 17.5 4.2 0.0015 17.2 4.2 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) ALS2CR8 PF15299.4 MSTRG.11395.1_1 - 0.012 15.4 1.3 0.014 15.2 1.3 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF342 PF03961.11 MSTRG.11395.1_1 - 0.013 14.0 1.0 0.014 13.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.4 MSTRG.11395.1_1 - 0.026 13.7 0.9 0.027 13.7 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCU PF04678.11 MSTRG.11395.1_1 - 0.045 13.8 1.5 0.053 13.5 1.5 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4337 PF14235.4 MSTRG.11395.1_1 - 0.081 12.9 4.5 0.13 12.3 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AMP-binding_C_2 PF14535.4 MSTRG.11395.1_1 - 0.084 13.1 0.9 0.12 12.5 0.7 1.5 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain IncA PF04156.12 MSTRG.11395.1_1 - 0.17 11.5 10.2 0.21 11.2 10.2 1.3 1 1 0 1 1 1 0 IncA protein Sec2p PF06428.9 MSTRG.11395.1_1 - 0.43 10.4 10.1 0.044 13.6 5.4 1.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p OmpH PF03938.12 MSTRG.11395.1_1 - 0.49 10.3 8.4 0.24 11.3 6.5 1.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.11 MSTRG.11395.1_1 - 1.7 7.7 5.3 0.7 8.9 3.2 1.4 2 0 0 2 2 2 0 TMPIT-like protein Mnd1 PF03962.13 MSTRG.11395.1_1 - 3.3 7.4 10.1 4.9 6.8 10.1 1.4 1 1 0 1 1 1 0 Mnd1 family Bap31 PF05529.10 MSTRG.11395.1_1 - 6.2 6.2 8.3 7.6 5.9 8.4 1.2 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Cation_ATPase_N PF00690.24 MSTRG.56866.1_3 - 6.7e-20 70.4 0.1 8.9e-20 70.0 0.1 1.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus XPC-binding PF09280.9 MSTRG.117269.1_1 - 2.3e-21 75.2 17.2 3.3e-21 74.6 17.2 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.29 MSTRG.117269.1_1 - 9.3e-13 47.7 0.4 1.7e-12 46.8 0.4 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.14 MSTRG.117269.1_1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 CUE domain UBA_3 PF09288.8 MSTRG.117269.1_1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Myb_DNA-bind_5 PF13873.4 MSTRG.131954.1_1 - 0.045 13.7 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain BRO1 PF03097.16 MSTRG.95208.1_1 - 1.3e-25 90.0 0.8 1.4e-25 89.8 0.8 1.0 1 0 0 1 1 1 1 BRO1-like domain Ig_3 PF13927.4 MSTRG.118409.1_2 - 8.9e-18 64.6 1.3 0.00012 22.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.118409.1_2 - 1.5e-14 54.0 1.9 9.9e-06 25.7 0.2 3.2 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.23 MSTRG.118409.1_2 - 2e-11 43.8 3.8 5.1e-05 23.2 0.5 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.14 MSTRG.118409.1_2 - 6.9e-10 38.7 0.2 0.00037 20.4 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.15 MSTRG.118409.1_2 - 2.5e-08 33.9 1.0 0.033 14.2 0.0 4.7 5 0 0 5 5 5 2 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.13 MSTRG.118409.1_2 - 0.0054 16.3 1.3 2.2 8.0 0.1 2.6 2 1 0 2 2 2 2 Adenovirus E3 region protein CR1 Ig_4 PF16680.3 MSTRG.118409.1_2 - 0.042 14.1 1.0 7.5 6.8 0.0 2.9 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain DUF814 PF05670.11 MSTRG.43902.1_2 - 7.1e-25 86.8 0.0 1.2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Septin PF00735.16 MSTRG.135601.1_1 - 2.6e-92 308.9 2.8 2.6e-92 308.9 2.8 1.6 2 0 0 2 2 2 1 Septin DUF3080 PF11279.6 MSTRG.135601.1_1 - 0.00023 20.3 3.1 0.00036 19.7 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) MMR_HSR1 PF01926.21 MSTRG.135601.1_1 - 0.00044 20.2 1.6 0.00061 19.7 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Fzo_mitofusin PF04799.11 MSTRG.135601.1_1 - 0.0033 16.8 5.1 0.0033 16.8 5.1 2.0 2 0 0 2 2 2 1 fzo-like conserved region Atg14 PF10186.7 MSTRG.135601.1_1 - 0.0035 16.3 7.9 0.0074 15.3 7.9 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2959 PF11172.6 MSTRG.135601.1_1 - 0.013 15.5 6.3 0.022 14.6 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Roc PF08477.11 MSTRG.135601.1_1 - 0.045 13.9 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF1890 PF09001.9 MSTRG.135601.1_1 - 0.054 13.8 0.2 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) TPR_MLP1_2 PF07926.10 MSTRG.135601.1_1 - 0.14 12.1 15.9 0.34 10.8 15.9 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein IMD PF08397.9 MSTRG.135601.1_1 - 0.18 11.1 16.1 0.093 12.0 13.8 1.6 2 0 0 2 2 2 0 IRSp53/MIM homology domain Exonuc_VII_L PF02601.13 MSTRG.135601.1_1 - 0.21 11.0 7.4 0.36 10.2 7.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.4 MSTRG.135601.1_1 - 0.72 9.0 4.3 0.97 8.6 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_11 PF13086.4 MSTRG.135601.1_1 - 0.87 9.1 8.1 1.6 8.3 8.1 1.4 1 0 0 1 1 1 0 AAA domain IncA PF04156.12 MSTRG.135601.1_1 - 1.8 8.2 13.8 3.4 7.3 13.8 1.4 1 0 0 1 1 1 0 IncA protein DUF87 PF01935.15 MSTRG.135601.1_1 - 2 8.3 7.7 8 6.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 RRM_1 PF00076.20 MSTRG.104857.1_1 - 1e-32 111.6 0.5 4e-07 29.6 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWWP PF00855.15 MSTRG.75794.1_1 - 0.011 16.1 0.0 5.1 7.5 0.0 2.1 2 0 0 2 2 2 0 PWWP domain HoxA13_N PF12284.6 MSTRG.75794.1_1 - 0.36 11.3 5.4 1.5 9.3 2.6 2.0 1 1 1 2 2 2 0 Hox protein A13 N terminal MCC-bdg_PDZ PF10506.7 MSTRG.138322.1_1 - 0.0037 17.1 3.0 0.14 12.0 0.2 2.4 2 0 0 2 2 2 2 PDZ domain of MCC-2 bdg protein for Usher syndrome Fez1 PF06818.13 MSTRG.138322.1_1 - 0.011 16.0 3.1 0.011 16.0 3.1 1.4 2 0 0 2 2 2 0 Fez1 KLRAQ PF10205.7 MSTRG.138322.1_1 - 0.017 15.2 0.9 0.017 15.2 0.9 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Fib_alpha PF08702.8 MSTRG.138322.1_1 - 0.018 15.1 4.3 0.025 14.6 3.5 1.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.3 MSTRG.138322.1_1 - 0.036 14.0 1.5 0.069 13.1 1.5 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2730 PF10805.6 MSTRG.138322.1_1 - 0.051 13.5 1.4 0.08 12.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ZapB PF06005.10 MSTRG.138322.1_1 - 0.089 13.1 2.8 0.12 12.7 0.6 2.0 1 1 1 2 2 2 0 Cell division protein ZapB NuDC PF16273.3 MSTRG.138322.1_1 - 0.15 12.5 3.1 11 6.5 0.0 3.0 3 0 0 3 3 3 0 Nuclear distribution C domain NifU PF01106.15 MSTRG.138322.1_1 - 0.15 12.1 0.2 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 NifU-like domain Spc24 PF08286.9 MSTRG.138322.1_1 - 0.28 11.3 4.3 0.3 11.2 0.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Myosin_tail_1 PF01576.17 MSTRG.88089.1_3 - 2.1e-29 101.9 51.1 2.4e-29 101.7 51.1 1.0 1 0 0 1 1 1 1 Myosin tail Alanine_zipper PF11839.6 MSTRG.88089.1_3 - 0.00012 22.2 29.4 0.0081 16.3 6.1 4.2 2 2 2 4 4 4 2 Alanine-zipper, major outer membrane lipoprotein BRE1 PF08647.9 MSTRG.88089.1_3 - 0.0037 17.2 19.1 0.0037 17.2 19.1 3.3 1 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase Tropomyosin PF00261.18 MSTRG.88089.1_3 - 0.0052 16.0 54.0 0.36 10.0 32.0 3.1 1 1 0 2 2 2 2 Tropomyosin Noelin-1 PF12308.6 MSTRG.88089.1_3 - 0.031 14.1 2.2 0.031 14.1 2.2 3.9 1 1 3 4 4 4 0 Neurogenesis glycoprotein Reo_sigmaC PF04582.10 MSTRG.88089.1_3 - 0.081 12.2 10.9 1 8.6 4.3 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GARP PF16731.3 MSTRG.88089.1_3 - 0.16 11.5 29.0 0.9 9.1 4.0 3.3 1 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Filament PF00038.19 MSTRG.88089.1_3 - 0.22 10.9 44.0 1.8 7.9 44.0 2.2 1 1 0 1 1 1 0 Intermediate filament protein Hydantoinase_A PF01968.16 MSTRG.88089.1_3 - 0.26 10.4 2.1 0.42 9.7 2.1 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase APG6 PF04111.10 MSTRG.88089.1_3 - 0.29 10.3 45.0 0.93 8.7 17.4 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.9 MSTRG.88089.1_3 - 0.4 10.7 51.3 0.28 11.2 14.1 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) IncA PF04156.12 MSTRG.88089.1_3 - 0.41 10.3 48.7 0.05 13.3 18.8 2.9 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.8 MSTRG.88089.1_3 - 0.51 10.4 28.5 0.076 13.1 14.1 3.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MAD PF05557.11 MSTRG.88089.1_3 - 0.8 7.8 47.1 3.5 5.7 47.1 1.9 1 1 0 1 1 1 0 Mitotic checkpoint protein CALCOCO1 PF07888.9 MSTRG.88089.1_3 - 1.2 7.5 43.7 1.9 6.8 43.7 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.17 MSTRG.88089.1_3 - 2.2 7.9 52.5 1.1 8.9 28.8 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family PAPS_reduct PF01507.17 MSTRG.88089.1_3 - 2.7 7.9 9.2 2.3 8.1 7.5 1.8 1 1 1 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Uso1_p115_C PF04871.11 MSTRG.88089.1_3 - 3.1 8.1 52.7 7.4 6.8 15.6 4.1 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region BLOC1_2 PF10046.7 MSTRG.88089.1_3 - 3.5 7.9 29.5 1.6 8.9 6.1 3.9 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.10 MSTRG.88089.1_3 - 4.1 7.4 52.5 1.1 9.2 20.6 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.10 MSTRG.88089.1_3 - 4.3 7.2 27.7 2.1 8.2 7.8 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.10 MSTRG.88089.1_3 - 4.8 6.6 45.7 22 4.4 45.2 2.5 1 1 0 1 1 1 0 PspA/IM30 family Tropomyosin_1 PF12718.5 MSTRG.88089.1_3 - 5.2 7.1 53.6 12 5.8 20.9 3.3 1 1 2 3 3 3 0 Tropomyosin like DUF724 PF05266.12 MSTRG.88089.1_3 - 5.2 6.7 41.4 0.66 9.6 6.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Tn7_Tnp_TnsA_C PF08721.9 MSTRG.88089.1_3 - 5.3 7.6 9.4 0.49 10.9 1.1 3.2 1 1 1 4 4 4 0 TnsA endonuclease C terminal Laminin_II PF06009.10 MSTRG.88089.1_3 - 5.5 6.9 33.3 2.9 7.8 9.4 3.8 1 1 2 3 3 3 0 Laminin Domain II BRI3BP PF14965.4 MSTRG.88089.1_3 - 5.9 6.2 10.8 1.6 8.1 0.6 3.1 3 0 0 3 3 3 0 Negative regulator of p53/TP53 DUF3037 PF11236.6 MSTRG.88089.1_3 - 6.1 7.2 14.4 2.9 8.2 5.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) DUF1049 PF06305.9 MSTRG.50069.1_1 - 0.0024 17.5 1.0 0.0028 17.3 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) DUF1191 PF06697.10 MSTRG.50069.1_1 - 0.026 13.6 0.3 0.029 13.5 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Herpes_gE PF02480.14 MSTRG.50069.1_1 - 0.058 12.0 0.1 0.064 11.9 0.1 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.4 MSTRG.50069.1_1 - 0.1 13.3 0.0 0.12 13.0 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM177 PF14774.4 MSTRG.1841.1_1 - 2.6e-47 159.9 1.2 3.1e-47 159.6 1.2 1.1 1 0 0 1 1 1 1 FAM177 family HTH_32 PF13565.4 MSTRG.37064.1_1 - 0.0059 17.1 0.1 0.0094 16.4 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.37064.1_1 - 0.055 13.6 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Transposase ANATO PF01821.16 MSTRG.37064.1_2 - 0.065 14.0 0.4 3.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Anaphylotoxin-like domain SH2 PF00017.22 MSTRG.41518.1_1 - 8.7e-16 57.6 0.0 1.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.26 MSTRG.41518.1_1 - 4.6e-10 38.8 0.1 9.2e-10 37.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 MSTRG.41518.1_1 - 9.2e-07 28.3 0.0 1.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 MSTRG.41518.1_1 - 2.4e-05 24.0 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MOZ_SAS PF01853.16 MSTRG.842.1_3 - 2.3e-32 111.9 1.7 3.2e-32 111.5 0.3 1.8 2 0 0 2 2 2 1 MOZ/SAS family DUF1509 PF07420.9 MSTRG.842.1_3 - 0.62 8.8 3.0 0.31 9.8 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) RHD_DNA_bind PF00554.20 MSTRG.110365.1_1 - 5.8e-14 52.3 0.1 3.7e-13 49.6 0.1 1.9 1 1 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 MSTRG.110365.1_1 - 1e-12 47.9 0.2 1.7e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain TIG PF01833.22 MSTRG.110365.1_1 - 0.0078 16.1 0.0 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 IPT/TIG domain DUF3971 PF13116.4 MSTRG.110365.1_1 - 0.071 12.5 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function eIF-5a PF01287.18 MSTRG.20170.3_3 - 1.3e-26 92.4 0.4 1.9e-26 91.8 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.10 MSTRG.20170.3_3 - 0.0051 16.7 0.4 0.01 15.7 0.1 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain BACK PF07707.13 MSTRG.142743.1_1 - 3.1e-10 39.9 0.0 5.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch SRCR PF00530.16 MSTRG.142743.1_1 - 6.7e-10 39.3 1.4 1.1e-09 38.5 0.3 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Peptidase_C1 PF00112.21 MSTRG.142743.1_1 - 0.017 15.1 0.3 0.075 13.0 0.2 2.0 2 0 0 2 2 2 0 Papain family cysteine protease RVT_1 PF00078.25 MSTRG.114126.1_2 - 3.1e-12 46.4 0.1 3.5e-12 46.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) XLF PF09302.9 MSTRG.114126.1_2 - 0.053 13.5 0.0 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component zf-H2C2_2 PF13465.4 MSTRG.14503.1_1 - 2.1e-11 43.6 10.9 1.8e-09 37.5 0.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.14503.1_1 - 5.7e-10 39.0 9.9 2.6e-06 27.4 2.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.14503.1_1 - 2.1e-09 37.3 8.0 3.3e-05 24.2 1.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.14503.1_1 - 1.6e-07 31.0 5.9 0.00011 21.9 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.14503.1_1 - 7.1e-06 26.1 4.6 0.0014 18.8 0.3 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 MSTRG.14503.1_1 - 3.4e-05 23.9 6.2 4.5e-05 23.6 1.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DZR PF12773.5 MSTRG.14503.1_1 - 0.00014 21.7 1.2 0.00016 21.5 1.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2256 PF10013.7 MSTRG.14503.1_1 - 0.00042 20.2 1.1 0.067 13.2 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-LYAR PF08790.9 MSTRG.14503.1_1 - 0.0011 18.7 10.5 0.0097 15.7 0.7 2.6 3 0 0 3 3 2 2 LYAR-type C2HC zinc finger SprT-like PF10263.7 MSTRG.14503.1_1 - 0.0013 18.4 1.7 0.0015 18.2 1.7 1.2 1 0 0 1 1 1 1 SprT-like family XPA_N PF01286.16 MSTRG.14503.1_1 - 0.0025 17.7 1.2 0.34 10.9 0.1 2.2 2 0 0 2 2 2 1 XPA protein N-terminal zf-C2HE PF16278.3 MSTRG.14503.1_1 - 0.0038 17.5 3.4 0.091 13.1 3.4 2.1 1 1 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.3 MSTRG.14503.1_1 - 0.0039 16.8 7.1 0.049 13.3 0.2 2.3 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-FCS PF06467.12 MSTRG.14503.1_1 - 0.0044 16.8 2.3 0.41 10.5 0.1 2.2 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.14 MSTRG.14503.1_1 - 0.0044 17.2 5.0 0.036 14.3 5.0 2.0 1 1 0 1 1 1 1 C1 domain C1_1 PF00130.20 MSTRG.14503.1_1 - 0.005 16.6 3.0 0.043 13.6 2.8 2.0 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.4 MSTRG.14503.1_1 - 0.0052 16.6 0.4 0.5 10.2 0.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.5 MSTRG.14503.1_1 - 0.0053 16.9 2.9 0.096 12.9 0.3 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) YhfH PF14149.4 MSTRG.14503.1_1 - 0.0075 16.1 0.5 0.69 9.8 0.0 2.2 2 0 0 2 2 2 1 YhfH-like protein zf-HIT PF04438.14 MSTRG.14503.1_1 - 0.0082 15.9 2.2 1.2 9.0 0.1 2.2 2 0 0 2 2 2 2 HIT zinc finger zinc_ribbon_15 PF17032.3 MSTRG.14503.1_1 - 0.01 16.4 1.0 0.013 16.1 1.0 1.1 1 0 0 1 1 1 0 zinc-ribbon family CpXC PF14353.4 MSTRG.14503.1_1 - 0.013 15.4 1.1 2.1 8.3 0.1 2.0 2 0 0 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.8 MSTRG.14503.1_1 - 0.016 15.2 3.6 0.3 11.1 3.2 2.1 1 1 2 3 3 3 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.9 MSTRG.14503.1_1 - 0.026 14.3 5.9 0.096 12.5 5.9 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-BED PF02892.13 MSTRG.14503.1_1 - 0.028 14.4 7.0 0.47 10.4 1.8 2.3 1 1 1 2 2 2 0 BED zinc finger FYVE PF01363.19 MSTRG.14503.1_1 - 0.22 11.5 7.9 2.6 8.1 7.9 2.0 1 1 0 1 1 1 0 FYVE zinc finger Vps39_2 PF10367.7 MSTRG.14503.1_1 - 0.24 11.7 2.3 1.4 9.3 0.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Zn_ribbon_recom PF13408.4 MSTRG.14503.1_1 - 0.71 10.3 6.0 1 9.8 5.9 1.5 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain A2L_zn_ribbon PF08792.8 MSTRG.14503.1_1 - 1.3 8.7 6.8 6.9 6.4 0.5 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain ARL17 PF15840.3 MSTRG.82976.1_3 - 0.14 12.4 2.0 2.3 8.5 0.3 2.4 2 1 0 2 2 2 0 ADP-ribosylation factor-like protein 17 BacteriocIIc_cy PF12173.6 MSTRG.42270.1_3 - 0.078 13.1 1.7 0.54 10.4 1.0 1.9 1 1 1 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like LIDHydrolase PF10230.7 MSTRG.63968.1_3 - 1.9e-22 80.0 0.0 2.3e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase zf-CSL PF05207.11 MSTRG.8298.1_2 - 3.1e-23 81.1 2.3 5.6e-23 80.3 2.3 1.4 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.13 MSTRG.8298.1_2 - 0.094 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain Oxysterol_BP PF01237.16 MSTRG.95344.2_1 - 2.6e-13 49.4 3.9 3.1e-13 49.2 3.9 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PMT PF02366.16 MSTRG.71450.1_3 - 1.2e-16 60.9 0.1 1.4e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase CARM1 PF11531.6 MSTRG.64370.1_1 - 0.057 13.5 0.0 0.065 13.3 0.0 1.1 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal Exo_endo_phos PF03372.21 MSTRG.29791.1_3 - 2.6e-06 27.5 0.0 4.8e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Aminotran_3 PF00202.19 MSTRG.29791.1_3 - 0.027 13.0 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III MmcB-like PF06319.10 MSTRG.29791.1_3 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 DNA repair protein MmcB-like HTH_Tnp_Tc3_2 PF01498.16 MSTRG.68705.1_3 - 3.9e-19 68.5 0.4 3.9e-19 68.5 0.4 1.9 2 0 0 2 2 2 1 Transposase Patched PF02460.16 MSTRG.22989.1_2 - 0.0084 14.1 0.3 0.0093 14.0 0.3 1.0 1 0 0 1 1 1 1 Patched family Atrophin-1 PF03154.13 MSTRG.22989.1_2 - 0.3 9.2 7.0 0.31 9.1 7.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 MSTRG.22989.1_3 - 3.9 7.3 11.8 6.4 6.7 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Pyrophosphatase PF00719.17 MSTRG.9494.1_1 - 4.5e-39 133.7 0.3 5.8e-39 133.3 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase HMG_box_5 PF14887.4 MSTRG.68855.1_2 - 6e-33 112.5 18.4 2.1e-32 110.8 4.7 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box 5 HMG_box PF00505.17 MSTRG.68855.1_2 - 6.8e-13 48.7 30.1 1.1e-05 25.6 1.5 5.3 3 3 2 5 5 5 3 HMG (high mobility group) box HMG_box_2 PF09011.8 MSTRG.68855.1_2 - 8.7e-10 38.9 26.9 9.2e-06 26.0 0.3 5.1 4 1 1 5 5 5 3 HMG-box domain DUF4473 PF14747.4 MSTRG.68855.1_2 - 0.0021 18.4 0.3 0.0021 18.4 0.3 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4473) DUF4414 PF14377.4 MSTRG.68855.1_2 - 0.096 12.8 2.4 0.17 12.0 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) JmjC PF02373.20 MSTRG.68855.1_2 - 6.2 7.2 7.2 16 5.8 0.4 2.9 3 0 0 3 3 3 0 JmjC domain, hydroxylase JmjC PF02373.20 MSTRG.30898.1_3 - 3.1e-10 40.4 0.8 5.7e-10 39.5 0.8 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Antimicrobial14 PF08109.9 MSTRG.41125.1_1 - 0.0088 15.9 11.3 1.5 8.8 0.4 3.4 3 0 0 3 3 3 3 Lactocin 705 family IQ PF00612.25 MSTRG.41125.1_2 - 0.36 10.6 12.5 13 5.8 0.1 4.3 4 0 0 4 4 4 0 IQ calmodulin-binding motif Glyco_hydro_65C PF03633.13 MSTRG.41125.1_2 - 4.3 7.2 9.6 38 4.2 0.8 3.6 1 1 2 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain PGM_PMM_IV PF00408.18 MSTRG.41125.1_3 - 0.045 13.8 0.0 5.2 7.2 0.0 2.6 1 1 2 3 3 3 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain YqfQ PF14181.4 MSTRG.41125.1_3 - 0.09 12.8 0.1 0.71 9.9 0.1 2.1 1 1 2 3 3 3 0 YqfQ-like protein HTH_Tnp_4 PF13613.4 MSTRG.48616.1_1 - 0.0013 18.3 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_4 PF13359.4 MSTRG.48616.1_3 - 0.00052 19.6 0.0 0.00091 18.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TGF_beta_GS PF08515.10 MSTRG.107563.1_2 - 2.6 7.5 6.1 3.6 7.0 0.2 2.2 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Dicty_CTDC PF00526.16 MSTRG.13412.1_1 - 0.28 11.0 3.0 0.55 10.1 0.2 2.1 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat MMR_HSR1_Xtn PF16897.3 MSTRG.143884.1_2 - 3.6e-43 145.8 0.2 5.6e-43 145.2 0.2 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.19 MSTRG.143884.1_2 - 7e-23 80.3 0.1 1.5e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.21 MSTRG.143884.1_2 - 1.8e-19 69.8 0.0 3.7e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.16 MSTRG.143884.1_2 - 2.7e-10 39.9 0.1 1.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.14 MSTRG.143884.1_2 - 0.0082 15.0 0.1 0.031 13.1 0.0 1.8 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.21 MSTRG.143884.1_2 - 0.0083 16.1 0.3 3.4 7.5 0.2 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.25 MSTRG.143884.1_2 - 0.087 12.2 0.1 16 4.8 0.0 3.5 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain Pkinase PF00069.23 MSTRG.86086.2_3 - 4.9e-16 58.7 0.2 6.2e-16 58.4 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.86086.2_3 - 4.1e-09 36.0 0.0 4.8e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YihI PF04220.10 MSTRG.140560.1_2 - 0.0019 17.8 9.0 0.0024 17.5 9.0 1.0 1 0 0 1 1 1 1 Der GTPase activator (YihI) Mpv17_PMP22 PF04117.10 MSTRG.126206.1_1 - 4.6e-05 23.4 2.9 8.5e-05 22.6 2.9 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family COX5B PF01215.17 MSTRG.53932.1_2 - 6.9e-06 25.7 0.1 8.3e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb HTH_Tnp_Tc3_2 PF01498.16 MSTRG.99717.1_3 - 0.00016 21.7 1.4 0.00028 20.9 1.4 1.4 1 0 0 1 1 1 1 Transposase DDE_Tnp_1_7 PF13843.4 MSTRG.31878.1_2 - 2.4e-09 36.8 0.0 2.8e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 RVT_1 PF00078.25 MSTRG.95250.1_3 - 6.7e-09 35.5 0.2 1.2e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M18 PF02127.13 MSTRG.95250.1_3 - 0.025 13.2 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) ubiquitin PF00240.21 MSTRG.21925.1_3 - 2e-34 117.0 0.3 2.7e-34 116.6 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.15 MSTRG.21925.1_3 - 5.1e-32 109.4 12.1 9.2e-32 108.5 12.1 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.6 MSTRG.21925.1_3 - 1.4e-16 59.9 0.4 2.2e-16 59.3 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 MSTRG.21925.1_3 - 1.5e-05 25.2 0.1 4.4e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.4 MSTRG.21925.1_3 - 0.012 15.6 0.0 0.021 14.8 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF963 PF06131.9 MSTRG.63447.1_3 - 0.023 13.9 1.9 0.56 9.5 0.2 2.1 1 1 1 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) S8_pro-domain PF16470.3 MSTRG.140688.1_3 - 6.1e-26 90.9 2.5 7.3e-26 90.7 2.5 1.1 1 0 0 1 1 1 1 Peptidase S8 pro-domain Amidase_6 PF12671.5 MSTRG.33824.1_3 - 0.026 14.5 1.7 9.3 6.2 0.0 3.9 3 1 1 4 4 4 0 Putative amidase domain BTB_2 PF02214.20 MSTRG.99626.2_3 - 1.8e-05 24.8 0.0 3.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Myb_Cef PF11831.6 MSTRG.117146.1_1 - 5.3e-63 212.6 7.3 5.3e-63 212.6 7.3 2.2 1 1 1 2 2 2 2 pre-mRNA splicing factor component PP1_bind PF15276.4 MSTRG.117146.1_1 - 0.15 12.3 2.2 0.74 10.1 0.2 3.2 3 0 0 3 3 3 0 Protein phosphatase 1 binding zf-C2H2_4 PF13894.4 MSTRG.42361.1_3 - 0.0022 18.5 1.1 0.0032 18.0 1.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.24 MSTRG.42361.1_3 - 0.01 16.1 1.8 0.014 15.7 1.8 1.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.42361.1_3 - 0.013 15.8 0.1 0.013 15.8 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double domain Calsarcin PF05556.9 MSTRG.109907.1_2 - 5e-26 91.5 0.0 5.5e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) EGF_CA PF07645.13 MSTRG.90333.2_2 - 1.3e-41 140.4 68.6 3.7e-12 46.1 7.9 5.0 5 0 0 5 5 5 5 Calcium-binding EGF domain cEGF PF12662.5 MSTRG.90333.2_2 - 4.2e-32 109.6 47.2 3.1e-08 33.3 1.8 6.2 6 0 0 6 6 6 5 Complement Clr-like EGF-like EGF_3 PF12947.5 MSTRG.90333.2_2 - 1.4e-11 44.3 59.4 0.0063 16.6 9.9 6.2 4 1 1 5 5 5 5 EGF domain FXa_inhibition PF14670.4 MSTRG.90333.2_2 - 3.9e-10 39.7 64.0 0.0011 19.1 9.1 5.6 4 1 1 5 5 5 5 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.9 MSTRG.90333.2_2 - 2.3e-08 34.0 45.4 0.0049 17.0 3.1 5.2 5 0 0 5 5 5 4 Pvs28 EGF domain EGF PF00008.25 MSTRG.90333.2_2 - 1.3e-07 31.6 62.0 0.0011 19.1 7.8 6.5 5 1 1 6 6 6 5 EGF-like domain hEGF PF12661.5 MSTRG.90333.2_2 - 6.9e-05 23.2 73.8 0.011 16.2 7.0 7.9 8 1 0 8 8 8 5 Human growth factor-like EGF EB PF01683.16 MSTRG.90333.2_2 - 0.047 13.8 67.6 0.4 10.8 6.9 6.8 1 1 3 4 4 4 0 EB module EGF_2 PF07974.11 MSTRG.90333.2_2 - 1.5 9.1 74.1 0.49 10.7 7.4 6.2 4 1 2 6 6 6 0 EGF-like domain POT1 PF02765.15 MSTRG.41198.1_3 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 AAA PF00004.27 MSTRG.45110.1_3 - 3.2e-44 150.4 0.1 1.3e-43 148.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 MSTRG.45110.1_3 - 1.3e-08 35.0 0.1 3.7e-08 33.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 MSTRG.45110.1_3 - 7.9e-08 32.3 0.1 2.6e-07 30.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 MSTRG.45110.1_3 - 3.8e-06 27.2 0.2 0.00082 19.7 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain DUF815 PF05673.11 MSTRG.45110.1_3 - 0.00012 21.2 0.2 0.00041 19.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.10 MSTRG.45110.1_3 - 0.00013 21.2 0.0 0.00037 19.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.4 MSTRG.45110.1_3 - 0.00025 21.2 0.6 0.054 13.6 0.0 2.8 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.20 MSTRG.45110.1_3 - 0.00033 20.9 0.0 0.00073 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.19 MSTRG.45110.1_3 - 0.00064 19.0 0.1 0.0014 18.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.4 MSTRG.45110.1_3 - 0.00079 19.3 0.1 0.0048 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.13 MSTRG.45110.1_3 - 0.00086 19.1 0.1 0.14 12.0 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.4 MSTRG.45110.1_3 - 0.0013 18.9 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 MSTRG.45110.1_3 - 0.0019 18.2 0.0 0.004 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.15 MSTRG.45110.1_3 - 0.0021 17.7 0.0 0.0077 15.9 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.4 MSTRG.45110.1_3 - 0.0038 17.6 0.0 0.021 15.2 0.0 2.2 1 1 0 2 2 2 1 AAA domain NACHT PF05729.10 MSTRG.45110.1_3 - 0.0045 16.8 0.1 0.042 13.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain CENP-F_leu_zip PF10473.7 MSTRG.45110.1_3 - 0.0057 16.5 0.5 0.011 15.7 0.5 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TIP49 PF06068.11 MSTRG.45110.1_3 - 0.007 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.24 MSTRG.45110.1_3 - 0.0072 15.9 0.2 0.56 9.8 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_3 PF07726.9 MSTRG.45110.1_3 - 0.009 15.7 0.1 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.15 MSTRG.45110.1_3 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.16 MSTRG.45110.1_3 - 0.019 14.8 0.9 0.16 11.7 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea DUF3450 PF11932.6 MSTRG.45110.1_3 - 0.045 12.9 2.8 0.075 12.2 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) AAA_23 PF13476.4 MSTRG.45110.1_3 - 0.053 13.9 2.7 10 6.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.4 MSTRG.45110.1_3 - 0.056 13.0 0.1 0.13 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.10 MSTRG.45110.1_3 - 0.057 12.6 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.4 MSTRG.45110.1_3 - 0.067 12.6 2.4 0.13 11.7 0.1 2.3 2 1 0 3 3 3 0 AAA domain NB-ARC PF00931.20 MSTRG.45110.1_3 - 0.082 11.8 0.1 0.26 10.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.15 MSTRG.45110.1_3 - 0.096 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.25 MSTRG.45110.1_3 - 0.13 12.6 0.0 0.49 10.8 0.0 2.1 2 1 0 2 2 2 0 ABC transporter DivIVA PF05103.11 MSTRG.45110.1_3 - 0.15 12.1 4.5 0.16 11.9 2.3 2.0 2 0 0 2 2 2 0 DivIVA protein AAA_30 PF13604.4 MSTRG.45110.1_3 - 0.15 11.6 0.1 0.34 10.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.11 MSTRG.45110.1_3 - 0.24 10.6 1.3 1.5 7.9 0.0 2.5 3 0 0 3 3 3 0 KaiC DUF2512 PF10710.7 MSTRG.142453.1_1 - 0.29 10.7 0.3 57 3.2 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2512) DUF3789 PF12664.5 MSTRG.142453.1_2 - 0.66 9.6 3.2 0.88 9.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Sel1 PF08238.10 MSTRG.144392.1_2 - 0.00022 21.7 1.3 0.00052 20.5 0.1 2.0 2 0 0 2 2 2 1 Sel1 repeat EGF_3 PF12947.5 MSTRG.113077.1_3 - 0.16 12.1 5.4 2.7 8.2 2.4 2.3 2 0 0 2 2 2 0 EGF domain HECT PF00632.23 MSTRG.28270.1_2 - 3.8e-43 148.0 0.0 4.7e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) EPV_E5 PF08135.9 MSTRG.92018.1_3 - 0.18 12.1 2.2 0.28 11.4 2.2 1.3 1 0 0 1 1 1 0 Major transforming protein E5 family DUF4187 PF13821.4 MSTRG.99916.1_2 - 0.18 11.5 0.8 0.33 10.6 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) ACC_central PF08326.10 MSTRG.88945.1_3 - 2.8e-25 88.5 0.2 3e-25 88.4 0.2 1.0 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region SRCR PF00530.16 MSTRG.43505.1_1 - 2.8e-06 27.6 7.8 8.1e-06 26.2 0.1 3.5 4 0 0 4 4 4 1 Scavenger receptor cysteine-rich domain DAN PF03045.13 MSTRG.32927.1_2 - 1.8e-40 137.3 7.0 2.1e-40 137.1 7.0 1.0 1 0 0 1 1 1 1 DAN domain zf-C3HC PF07967.11 MSTRG.94238.1_1 - 0.028 14.2 0.6 0.036 13.9 0.6 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like DUF2138 PF09909.7 MSTRG.16458.1_2 - 0.27 9.4 0.1 0.28 9.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) DDE_3 PF13358.4 MSTRG.100133.1_1 - 9.1e-06 25.4 0.2 1.1e-05 25.1 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.20 MSTRG.76639.1_3 - 6.3e-16 57.8 0.0 8.1e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.21 MSTRG.76639.1_3 - 9.7e-05 22.1 6.8 0.00018 21.3 6.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.4 MSTRG.76639.1_3 - 0.00061 19.2 0.0 0.00075 19.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.4 MSTRG.76639.1_3 - 0.00093 19.0 0.9 0.00093 19.0 0.9 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.4 MSTRG.76639.1_3 - 0.015 14.9 0.8 0.027 14.1 0.8 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger BUD22 PF09073.8 MSTRG.76837.1_3 - 6.4 5.9 26.8 7.7 5.6 26.8 1.1 1 0 0 1 1 1 0 BUD22 Phage_holin_3_6 PF07332.9 MSTRG.97872.1_2 - 4.3 7.3 8.2 6.6 6.7 8.2 1.5 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Hist_deacetyl PF00850.17 MSTRG.58212.1_3 - 2.6e-33 115.7 0.0 2.7e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain RVT_1 PF00078.25 MSTRG.1145.1_2 - 2.6e-09 36.8 0.0 3.2e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cellsynth_D PF03500.11 MSTRG.10473.1_2 - 0.02 14.7 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Cellulose synthase subunit D RNase_PH PF01138.19 MSTRG.87775.1_2 - 1.7e-13 51.1 0.0 2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Doppel PF11466.6 MSTRG.26226.1_3 - 0.89 9.1 4.6 8.5 6.0 0.7 2.5 2 0 0 2 2 2 0 Prion-like protein Doppel EMP24_GP25L PF01105.22 MSTRG.35390.1_1 - 1.1e-12 48.1 0.4 1.5e-12 47.7 0.4 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PHO4 PF01384.18 MSTRG.96234.1_3 - 1.4e-37 129.4 6.2 1.4e-37 129.3 6.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Carn_acyltransf PF00755.18 MSTRG.6010.1_3 - 1.6e-78 264.7 0.4 1.8e-78 264.5 0.4 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF4753 PF15945.3 MSTRG.108098.1_1 - 0.13 12.0 5.6 6.2 6.6 0.1 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4753) Motilin_assoc PF04643.10 MSTRG.108098.1_3 - 0.11 12.2 0.6 62 3.4 0.0 3.5 3 1 1 4 4 4 0 Motilin/ghrelin-associated peptide SAP PF02037.25 MSTRG.53230.1_3 - 1e-09 37.8 1.1 1e-09 37.8 1.1 2.5 3 0 0 3 3 3 1 SAP domain TPR_19 PF14559.4 MSTRG.79604.1_3 - 0.019 15.3 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.4 MSTRG.79604.1_3 - 0.062 14.0 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 MSTRG.79604.1_3 - 0.092 12.7 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat IL13 PF03487.11 MSTRG.5628.1_1 - 0.0036 17.1 0.0 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 Interleukin-13 Lectin_C PF00059.19 MSTRG.42896.1_3 - 0.00025 21.6 0.0 0.00042 20.9 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain GST_C_2 PF13410.4 MSTRG.42896.1_3 - 0.094 12.6 0.1 0.13 12.1 0.1 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WWE PF02825.18 MSTRG.47298.2_2 - 1.2e-15 57.6 4.3 1.6e-15 57.2 1.8 2.4 2 0 0 2 2 2 1 WWE domain Torus PF16131.3 MSTRG.47298.2_2 - 0.0012 19.4 0.8 0.0012 19.4 0.8 3.5 3 1 0 3 3 3 1 Torus domain zf-CCCH PF00642.22 MSTRG.47298.2_2 - 0.81 9.5 29.1 0.26 11.1 1.1 5.2 3 2 1 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.9 MSTRG.64310.1_2 - 0.045 13.6 0.1 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster Zn_Tnp_IS1595 PF12760.5 MSTRG.64310.1_2 - 0.078 12.8 0.5 0.53 10.2 0.1 2.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain UQ_con PF00179.24 MSTRG.105792.2_1 - 3.4e-12 46.1 0.0 4.8e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.24 MSTRG.105792.2_2 - 2.9e-25 88.4 0.0 1.1e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.20 MSTRG.105792.2_2 - 0.17 12.1 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 RWD domain SSTK-IP PF15836.3 MSTRG.23617.1_2 - 0.011 15.7 0.1 0.013 15.5 0.1 1.1 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Myosin_tail_1 PF01576.17 MSTRG.103341.1_3 - 2.2e-20 72.0 22.3 2.4e-20 71.9 22.3 1.0 1 0 0 1 1 1 1 Myosin tail Bacillus_HBL PF05791.9 MSTRG.103341.1_3 - 0.038 13.6 0.5 0.038 13.6 0.5 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PEGA PF08308.9 MSTRG.103341.1_3 - 0.043 13.6 0.2 0.074 12.8 0.2 1.4 1 0 0 1 1 1 0 PEGA domain DUF3584 PF12128.6 MSTRG.103341.1_3 - 0.28 8.5 18.4 0.33 8.3 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TrbI_Ftype PF09677.8 MSTRG.103341.1_3 - 0.29 11.3 4.0 0.42 10.8 2.5 2.0 1 1 1 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) APG6 PF04111.10 MSTRG.103341.1_3 - 0.32 10.2 18.0 0.41 9.9 18.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.11 MSTRG.103341.1_3 - 0.8 9.3 18.1 0.58 9.8 10.4 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3523 PF12037.6 MSTRG.103341.1_3 - 0.83 8.8 20.0 1.1 8.5 20.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) IncA PF04156.12 MSTRG.103341.1_3 - 1.3 8.7 22.8 2.4 7.8 22.9 1.4 1 1 0 1 1 1 0 IncA protein DUF1664 PF07889.10 MSTRG.103341.1_3 - 1.5 8.7 13.9 3.2 7.6 7.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.13 MSTRG.103341.1_3 - 2.6 7.4 11.3 3.3 7.0 11.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5082 PF16888.3 MSTRG.103341.1_3 - 2.9 8.1 17.4 55 4.0 17.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) CorA PF01544.16 MSTRG.103341.1_3 - 4.5 6.4 10.4 5.5 6.1 10.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.8 MSTRG.103341.1_3 - 9.5 6.3 14.3 12 6.0 0.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ALMT PF11744.6 MSTRG.103341.1_3 - 9.7 4.7 12.9 12 4.4 12.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HTH_Tnp_Tc3_2 PF01498.16 MSTRG.126854.1_2 - 1.9e-07 31.1 0.1 2.4e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Transposase Toxin_R_bind_C PF07951.10 MSTRG.126854.1_3 - 0.23 10.9 0.4 0.29 10.6 0.4 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Drf_FH1 PF06346.10 MSTRG.19995.1_2 - 0.74 9.4 12.6 0.83 9.2 12.6 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 UPF0016 PF01169.17 MSTRG.116973.1_3 - 1.1e-21 76.8 8.4 1.9e-21 76.0 8.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 Bac_export_2 PF01312.17 MSTRG.116973.1_3 - 0.099 11.7 1.0 0.1 11.6 0.2 1.4 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family zf-ZPR1 PF03367.11 MSTRG.88833.2_1 - 9.2e-36 123.0 0.1 1.2e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain zf-ZPR1 PF03367.11 MSTRG.88833.2_2 - 2.8e-08 33.6 0.0 3.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ZPR1 zinc-finger domain CSTF_C PF14304.4 MSTRG.85658.1_2 - 1.5e-20 72.3 10.4 2.3e-20 71.8 10.4 1.3 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Homeobox_KN PF05920.9 MSTRG.23930.1_2 - 8.8e-21 73.4 1.0 2e-20 72.3 1.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.27 MSTRG.23930.1_2 - 1.6e-08 34.1 0.4 2.9e-08 33.3 0.4 1.4 1 0 0 1 1 1 1 Homeobox domain IBR PF01485.19 MSTRG.143253.3_2 - 0.00074 19.6 4.3 0.0013 18.8 4.3 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain OTT_1508_deam PF14441.4 MSTRG.143253.3_2 - 0.1 12.4 1.8 0.2 11.5 1.8 1.5 1 0 0 1 1 1 0 OTT_1508-like deaminase DUF1289 PF06945.11 MSTRG.22587.1_2 - 0.016 14.9 2.0 3.7 7.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DOCK-C2 PF14429.4 MSTRG.79390.1_1 - 3.2e-07 30.3 0.0 6.6e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins V_ATPase_I PF01496.17 MSTRG.24045.1_2 - 1e-60 205.5 8.7 1.1e-60 205.3 8.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3021 PF11457.6 MSTRG.24045.1_2 - 1.1 9.5 11.2 0.095 12.9 6.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Vps8 PF12816.5 MSTRG.124641.1_1 - 0.039 13.3 1.9 4.2 6.7 0.1 2.7 3 0 0 3 3 3 0 Golgi CORVET complex core vacuolar protein 8 Cwf_Cwc_15 PF04889.10 MSTRG.60825.1_3 - 0.0016 18.1 7.2 0.0019 17.8 7.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.8 MSTRG.60825.1_3 - 0.11 11.7 13.0 0.14 11.3 13.0 1.1 1 0 0 1 1 1 0 BUD22 Na_trans_assoc PF06512.11 MSTRG.60825.1_3 - 1.1 9.4 10.0 1.4 9.1 10.0 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated NARP1 PF12569.6 MSTRG.60825.1_3 - 1.3 7.7 5.2 2 7.1 5.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DNA_pol_phi PF04931.11 MSTRG.60825.1_3 - 3.5 5.5 10.7 4.3 5.2 10.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi YebO PF13974.4 MSTRG.60825.1_3 - 7.6 6.6 8.6 0.31 11.0 2.8 1.7 2 0 0 2 2 2 0 YebO-like protein PAT1 PF09770.7 MSTRG.60825.1_3 - 9.5 4.2 8.4 12 3.9 8.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Filament PF00038.19 MSTRG.91642.7_2 - 5.9e-86 288.7 24.6 6.6e-86 288.6 24.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.10 MSTRG.91642.7_2 - 0.00054 19.9 26.4 0.0053 16.7 1.8 4.0 1 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.7 MSTRG.91642.7_2 - 0.002 18.0 23.5 0.024 14.5 6.1 4.0 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.10 MSTRG.91642.7_2 - 0.0054 16.6 15.4 0.23 11.3 3.7 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) DUF2461 PF09365.8 MSTRG.91642.7_2 - 0.019 14.8 1.3 0.072 12.9 0.2 2.1 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) Atg14 PF10186.7 MSTRG.91642.7_2 - 0.042 12.8 17.1 4.2 6.2 17.1 2.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.7 MSTRG.91642.7_2 - 0.13 12.4 23.6 2.2 8.4 4.6 3.8 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Gp-FAR-1 PF05823.10 MSTRG.91642.7_2 - 0.14 12.4 4.7 0.06 13.5 1.4 2.1 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Matrilin_ccoil PF10393.7 MSTRG.91642.7_2 - 0.24 11.2 2.5 0.95 9.2 0.1 3.2 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin FAM76 PF16046.3 MSTRG.91642.7_2 - 1.9 7.7 14.7 0.5 9.6 4.7 2.4 1 1 1 2 2 2 0 FAM76 protein EMP24_GP25L PF01105.22 MSTRG.91642.7_2 - 2.6 7.8 11.8 5.5 6.8 0.2 2.9 1 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD HIP1_clath_bdg PF16515.3 MSTRG.91642.7_2 - 2.8 8.5 22.9 7.2 7.2 12.4 3.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Noelin-1 PF12308.6 MSTRG.91642.7_2 - 4.1 7.3 9.9 2.4 8.1 0.3 3.3 2 1 1 3 3 3 0 Neurogenesis glycoprotein NPA PF16469.3 MSTRG.91642.7_2 - 4.5 7.8 10.7 3.4 8.2 5.2 3.0 2 2 0 2 2 2 0 Nematode polyprotein allergen ABA-1 IncA PF04156.12 MSTRG.91642.7_2 - 6.5 6.4 25.1 1.2 8.8 1.6 3.2 1 1 2 3 3 3 0 IncA protein DivIC PF04977.13 MSTRG.91642.7_2 - 7.5 6.3 16.1 6.4 6.5 0.4 4.8 5 0 0 5 5 5 0 Septum formation initiator NYD-SP28_assoc PF14775.4 MSTRG.91642.7_2 - 9.1 6.3 10.3 5.3 7.1 0.7 3.5 3 1 1 4 4 4 0 Sperm tail C-terminal domain SAM_1 PF00536.28 MSTRG.108901.1_1 - 6.2e-19 68.1 0.3 7.6e-19 67.8 0.3 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 MSTRG.108901.1_1 - 1.8e-11 43.8 0.1 2.2e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FliMN_C PF01052.18 MSTRG.108901.1_1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Roc PF08477.11 MSTRG.110274.1_1 - 0.01 15.9 0.2 0.016 15.3 0.2 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 MSTRG.110274.1_1 - 0.02 14.3 0.2 0.029 13.8 0.2 1.3 1 0 0 1 1 1 0 Ras family MMR_HSR1 PF01926.21 MSTRG.110274.1_1 - 0.093 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PA28_beta PF02252.16 MSTRG.21714.1_1 - 1.1e-57 193.7 1.2 2.2e-57 192.7 1.2 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.16 MSTRG.21714.1_1 - 1.2e-21 76.5 0.5 1.2e-21 76.5 0.5 1.9 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit Nckap1 PF09735.7 MSTRG.123392.1_3 - 9.2e-31 106.6 0.2 9.9e-31 106.5 0.2 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein RecG_N PF17190.2 MSTRG.123392.1_3 - 0.035 14.7 0.0 0.042 14.4 0.0 1.2 1 0 0 1 1 1 0 RecG N-terminal helical domain Kinesin PF00225.21 MSTRG.124065.1_2 - 5.7e-29 101.0 0.0 6.3e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Pur_ac_phosph_N PF16656.3 MSTRG.131399.1_3 - 0.1 13.1 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Exo_endo_phos_2 PF14529.4 MSTRG.114976.1_2 - 0.0015 18.2 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Stc1 PF12898.5 MSTRG.117890.1_2 - 0.0085 16.5 0.4 0.01 16.2 0.4 1.1 1 0 0 1 1 1 1 Stc1 domain zinc-ribbons_6 PF07191.10 MSTRG.117890.1_2 - 0.03 14.2 1.8 0.041 13.8 1.8 1.2 1 0 0 1 1 1 0 zinc-ribbons DDE_3 PF13358.4 MSTRG.117890.1_2 - 0.044 13.4 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease RRM_1 PF00076.20 MSTRG.128.4_3 - 7.9e-27 92.7 0.0 1e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.9 MSTRG.128.4_3 - 2.1e-06 27.5 0.0 0.076 12.9 0.0 2.9 2 2 0 2 2 2 2 RNA binding domain RRM_7 PF16367.3 MSTRG.128.4_3 - 5e-05 23.2 0.0 0.047 13.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.4 MSTRG.128.4_3 - 0.01 15.9 1.0 11 6.1 0.4 3.1 1 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.4 MSTRG.128.4_3 - 0.11 11.9 0.0 0.94 8.9 0.0 2.0 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.4 MSTRG.128.4_3 - 0.18 11.3 0.6 0.74 9.4 0.0 2.2 3 0 0 3 3 3 0 Sporulation protein family 7 SnAC PF14619.4 MSTRG.58999.1_3 - 1.6e-18 67.0 10.0 1.6e-18 67.0 10.0 2.9 2 2 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.29 MSTRG.58999.1_3 - 8.8e-07 29.2 0.2 2.9e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RGCC PF15151.4 MSTRG.49615.1_1 - 3.6e-31 108.1 1.3 4.8e-31 107.7 1.3 1.1 1 0 0 1 1 1 1 Response gene to complement 32 protein family DUF3341 PF11821.6 MSTRG.108418.1_1 - 0.0061 16.1 0.8 0.0062 16.1 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) VWA PF00092.26 MSTRG.115064.1_1 - 2.8e-06 27.6 0.0 3.1e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Filament PF00038.19 MSTRG.91642.10_2 - 2.4e-86 290.0 23.9 2.6e-86 289.9 23.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.10 MSTRG.91642.10_2 - 0.0018 18.2 27.0 0.015 15.2 2.0 4.0 2 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.7 MSTRG.91642.10_2 - 0.012 15.5 23.9 0.021 14.7 5.9 3.7 1 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.10 MSTRG.91642.10_2 - 0.022 14.6 15.1 0.21 11.4 3.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2461 PF09365.8 MSTRG.91642.10_2 - 0.028 14.2 1.1 0.12 12.2 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) Atg14 PF10186.7 MSTRG.91642.10_2 - 0.033 13.1 16.6 1 8.2 16.6 2.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Gp-FAR-1 PF05823.10 MSTRG.91642.10_2 - 0.16 12.2 5.1 0.06 13.5 1.4 2.2 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Matrilin_ccoil PF10393.7 MSTRG.91642.10_2 - 0.27 11.0 2.7 0.95 9.2 0.1 3.2 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin UPF0184 PF03670.11 MSTRG.91642.10_2 - 0.28 11.5 4.2 1.8 8.9 0.0 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) HIP1_clath_bdg PF16515.3 MSTRG.91642.10_2 - 1.5 9.3 22.1 7.2 7.2 12.4 3.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NPA PF16469.3 MSTRG.91642.10_2 - 2.7 8.6 10.0 3.4 8.2 5.2 2.9 2 1 0 2 2 2 0 Nematode polyprotein allergen ABA-1 EMP24_GP25L PF01105.22 MSTRG.91642.10_2 - 4.9 6.9 12.0 7.2 6.4 0.3 2.8 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD Noelin-1 PF12308.6 MSTRG.91642.10_2 - 5.5 6.9 10.4 2.4 8.1 0.4 3.3 2 1 1 3 3 3 0 Neurogenesis glycoprotein FAM76 PF16046.3 MSTRG.91642.10_2 - 6.2 6.0 15.4 3.6 6.7 6.4 2.5 1 1 1 2 2 2 0 FAM76 protein FixS PF03597.13 MSTRG.117433.1_2 - 0.031 13.8 0.1 0.044 13.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type CD52 PF15116.4 MSTRG.132051.1_3 - 0.04 13.8 5.0 0.31 11.0 0.5 2.3 2 0 0 2 2 2 0 CAMPATH-1 antigen Strabismus PF06638.9 MSTRG.132051.1_3 - 0.98 7.9 1.9 1 7.8 1.9 1.0 1 0 0 1 1 1 0 Strabismus protein RhoGEF PF00621.18 MSTRG.86433.1_3 - 2.2e-07 31.2 0.0 2.3e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain Peptidase_C1_2 PF03051.13 MSTRG.12246.1_1 - 2e-78 264.0 0.0 2.4e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Elf-1_N PF12310.6 MSTRG.5606.1_2 - 6.8e-23 81.2 1.9 6.8e-23 81.2 1.9 1.9 2 0 0 2 2 2 1 Transcription factor protein N terminal CTP_transf_1 PF01148.18 MSTRG.71086.1_2 - 4.7e-09 36.3 0.0 4.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family M157 PF11624.6 MSTRG.71086.1_2 - 0.091 12.0 0.1 0.14 11.3 0.1 1.4 1 1 0 1 1 1 0 MHC class I-like protein M157 PH PF00169.27 MSTRG.3223.1_1 - 2.1e-06 28.0 0.1 2.7e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 PH domain FeoC PF09012.8 MSTRG.3223.1_1 - 0.027 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator Pentapeptide_4 PF13599.4 MSTRG.113456.2_3 - 0.0046 16.9 0.0 0.0067 16.4 0.0 1.3 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) CLASP_N PF12348.6 MSTRG.20679.1_1 - 5.3e-13 48.9 0.0 3.5e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.20 MSTRG.20679.1_1 - 1.4e-08 34.1 0.2 1 9.7 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.4 MSTRG.20679.1_1 - 3.5e-07 30.4 0.0 0.47 10.7 0.0 3.9 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.5 MSTRG.20679.1_1 - 9.3e-06 25.6 0.2 0.3 10.9 0.1 3.9 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.7 MSTRG.20679.1_1 - 0.00023 20.6 0.0 0.18 11.2 0.0 2.5 1 1 1 2 2 2 2 Tti2 family ParcG PF10274.7 MSTRG.20679.1_1 - 0.012 15.6 0.0 0.051 13.6 0.0 2.0 2 0 0 2 2 2 0 Parkin co-regulated protein SnoaL_4 PF13577.4 MSTRG.20679.1_1 - 0.034 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain RIX1 PF08167.10 MSTRG.20679.1_1 - 0.035 13.7 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.5 MSTRG.20679.1_1 - 0.067 13.6 0.2 0.77 10.2 0.0 2.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Mlf1IP PF10248.7 MSTRG.34944.1_3 - 2e-61 206.7 1.4 3.2e-61 206.1 1.4 1.2 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein zf-MIZ PF02891.18 MSTRG.77465.1_3 - 0.052 13.2 1.1 0.074 12.7 1.1 1.2 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RhoGAP PF00620.25 MSTRG.90101.1_1 - 3.9e-13 49.4 0.0 5.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Tox-PL-2 PF15643.4 MSTRG.90101.1_1 - 0.082 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Papain fold toxin 2 Cytomega_TRL10 PF06084.9 MSTRG.63587.1_2 - 1 9.2 5.2 1.2 9.1 5.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Troponin PF00992.18 MSTRG.63251.1_3 - 2.9e-27 95.4 41.4 2e-26 92.7 35.8 2.2 1 1 1 2 2 2 2 Troponin CTNNB1_binding PF08347.9 MSTRG.63251.1_3 - 7 6.7 14.5 1.5 8.9 7.4 2.6 1 1 2 3 3 3 0 N-terminal CTNNB1 binding TINF2_N PF14973.4 MSTRG.4760.1_2 - 6.7e-18 65.3 0.0 7.2e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 TERF1-interacting nuclear factor 2 N-terminus Band_7 PF01145.23 MSTRG.1467.1_2 - 0.0027 17.6 0.2 0.0037 17.2 0.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.23 MSTRG.104020.1_2 - 4e-63 213.1 0.2 1e-62 211.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.104020.1_2 - 1.6e-29 102.9 0.0 1.6e-29 102.9 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.4 MSTRG.104020.1_2 - 3.7e-07 29.6 0.6 1.8e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like HR1 PF02185.14 MSTRG.104020.1_2 - 3.3e-06 27.0 11.9 3.3e-06 27.0 11.9 2.5 2 0 0 2 2 2 1 Hr1 repeat APH PF01636.21 MSTRG.104020.1_2 - 6.1e-05 22.9 0.3 0.0087 15.9 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Cortex-I_coil PF09304.8 MSTRG.104020.1_2 - 0.00025 21.1 10.6 0.00025 21.1 10.6 2.2 1 1 1 2 2 2 1 Cortexillin I, coiled coil Seadorna_VP7 PF07387.9 MSTRG.104020.1_2 - 0.01 14.8 0.1 0.01 14.8 0.1 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_C PF00433.22 MSTRG.104020.1_2 - 0.019 15.5 5.5 0.099 13.2 5.5 2.2 1 1 0 1 1 1 0 Protein kinase C terminal domain EzrA PF06160.10 MSTRG.104020.1_2 - 0.12 10.4 21.5 0.17 9.9 21.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1664 PF07889.10 MSTRG.104020.1_2 - 0.16 11.8 18.9 0.58 10.0 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Lzipper-MIP1 PF14389.4 MSTRG.104020.1_2 - 0.43 10.7 17.1 4.6 7.4 1.3 2.9 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Tropomyosin PF00261.18 MSTRG.104020.1_2 - 0.46 9.7 24.5 1.7 7.8 23.2 1.9 1 1 1 2 2 2 0 Tropomyosin DUF4407 PF14362.4 MSTRG.104020.1_2 - 1.2 8.3 12.0 1.6 7.8 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CC2-LZ PF16516.3 MSTRG.104020.1_2 - 1.8 8.8 19.5 0.74 10.0 7.7 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Golgin_A5 PF09787.7 MSTRG.104020.1_2 - 1.8 7.8 23.5 2.3 7.4 8.3 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 CHDCT2 PF08074.9 MSTRG.104020.1_2 - 8.4 6.4 12.4 1.3e+02 2.6 12.4 2.2 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain SRP9-21 PF05486.10 MSTRG.13694.1_3 - 1.6 9.0 9.3 5.8 7.3 1.4 2.3 1 1 1 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) MHCassoc_trimer PF08831.8 MSTRG.40089.1_2 - 0.072 13.0 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Phe_tRNA-synt_N PF02912.16 MSTRG.31728.1_3 - 0.049 13.4 0.1 0.089 12.6 0.1 1.4 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF1515 PF07439.9 MSTRG.31728.1_3 - 0.051 13.4 0.7 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Med21 PF11221.6 MSTRG.31728.1_3 - 0.088 12.9 0.4 0.15 12.2 0.4 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Imm71 PF15602.4 MSTRG.31728.1_3 - 0.12 11.9 0.0 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 Immunity protein 71 MerC PF03203.12 MSTRG.33839.1_3 - 0.068 13.5 1.5 0.069 13.5 1.5 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein Kringle PF00051.16 MSTRG.122435.1_2 - 5.6e-12 45.7 0.6 9.6e-11 41.7 0.0 2.0 2 0 0 2 2 2 2 Kringle domain ADH_zinc_N PF00107.24 MSTRG.7347.1_3 - 9.5e-16 57.7 0.0 1.3e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.4 MSTRG.7347.1_3 - 1.7e-08 35.4 0.0 2e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MHC_I PF00129.16 MSTRG.43504.2_3 - 2.2e-42 144.5 1.2 2.9e-42 144.1 1.2 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 MSTRG.43504.2_3 - 5e-08 33.2 0.1 1.2e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain vWA-TerF-like PF10138.7 MSTRG.43504.2_3 - 0.046 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus MHC_I_3 PF16497.3 MSTRG.43504.2_3 - 0.047 13.0 0.4 0.07 12.5 0.4 1.2 1 0 0 1 1 1 0 MHC-I family domain AGP PF06376.10 MSTRG.134187.1_1 - 0.33 10.7 1.6 0.49 10.1 1.6 1.2 1 0 0 1 1 1 0 Arabinogalactan peptide DUF2039 PF10217.7 MSTRG.94271.1_1 - 2e-30 104.8 18.9 3.7e-30 104.0 18.9 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.7 MSTRG.94271.1_1 - 0.0024 18.3 18.9 0.03 14.7 18.9 2.2 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.10 MSTRG.94271.1_1 - 0.008 16.0 10.5 0.016 15.1 10.5 1.4 1 0 0 1 1 1 1 zinc-ribbons DZR PF12773.5 MSTRG.94271.1_1 - 0.55 10.2 11.0 18 5.3 10.9 2.5 1 1 0 1 1 1 0 Double zinc ribbon HTH_28 PF13518.4 MSTRG.48842.1_1 - 2.8e-06 27.2 2.6 4.4e-06 26.6 2.6 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.4 MSTRG.48842.1_1 - 2.4e-05 24.1 1.2 3.9e-05 23.5 1.2 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.13 MSTRG.48842.1_1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.4 MSTRG.48842.1_1 - 0.00023 20.4 1.2 0.00038 19.7 1.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.4 MSTRG.48842.1_1 - 0.00037 20.1 0.3 0.00057 19.5 0.3 1.3 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.16 MSTRG.48842.1_1 - 0.0019 18.0 0.1 0.0024 17.6 0.1 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_38 PF13936.4 MSTRG.48842.1_1 - 0.0041 16.7 0.0 0.0063 16.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.11 MSTRG.48842.1_1 - 0.0061 16.0 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR_2 PF12802.5 MSTRG.48842.1_1 - 0.029 14.1 0.7 0.044 13.5 0.7 1.4 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.4 MSTRG.48842.1_1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding rve PF00665.24 MSTRG.29972.1_3 - 0.00062 19.8 0.0 0.00075 19.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain PA_decarbox PF05870.9 MSTRG.29972.1_3 - 0.012 15.2 0.0 0.013 15.0 0.0 1.0 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) RhoGEF PF00621.18 MSTRG.116922.1_3 - 3e-12 47.0 0.2 4.8e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain HSA PF07529.11 MSTRG.116922.1_3 - 0.039 14.2 0.3 0.054 13.7 0.3 1.3 1 0 0 1 1 1 0 HSA RNA_pol_3_Rpc31 PF11705.6 MSTRG.70567.1_3 - 0.0001 22.5 24.0 0.00012 22.2 24.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 MAS20 PF02064.13 MSTRG.70567.1_3 - 1.5 8.8 4.3 1.7 8.6 4.3 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor Laminin_N PF00055.15 MSTRG.48124.1_2 - 5.4e-23 81.7 0.0 6e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) HTH_23 PF13384.4 MSTRG.120429.1_2 - 0.0018 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.4 MSTRG.120429.1_2 - 0.003 17.2 0.1 0.006 16.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_12 PF13424.4 MSTRG.88925.1_3 - 5.2e-21 74.6 13.3 1.8e-09 37.6 1.0 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.4 MSTRG.88925.1_3 - 8.9e-17 60.3 2.6 7.5e-09 35.1 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.4 MSTRG.88925.1_3 - 1.9e-08 33.6 2.2 0.0014 18.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.26 MSTRG.88925.1_3 - 2.8e-07 29.9 8.3 8.7e-05 22.0 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.4 MSTRG.88925.1_3 - 3.4e-05 23.6 6.7 0.012 15.7 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.15 MSTRG.88925.1_3 - 0.0085 16.0 4.7 1.5 9.0 0.3 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR PF01535.18 MSTRG.88925.1_3 - 0.18 12.0 0.5 13 6.2 0.1 3.0 3 0 0 3 3 3 0 PPR repeat PET PF06297.12 MSTRG.136019.1_3 - 2.5e-33 114.1 1.3 2.8e-33 113.9 1.3 1.0 1 0 0 1 1 1 1 PET Domain RVT_1 PF00078.25 MSTRG.67938.1_1 - 0.0079 15.6 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AC_N PF16214.3 MSTRG.61123.1_3 - 0.13 11.2 0.9 0.13 11.2 0.9 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF4637 PF15470.4 MSTRG.61123.1_3 - 5.2 6.7 8.0 8.8 6.0 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CHDNT PF08073.10 MSTRG.18008.1_2 - 9.2e-05 22.1 0.9 0.00016 21.4 0.9 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF1777 PF08648.10 MSTRG.18008.1_2 - 0.12 12.5 19.0 0.15 12.1 19.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF4551 PF15087.4 MSTRG.18008.1_2 - 2.5 6.7 9.2 2.8 6.6 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hydin_ADK PF17213.1 MSTRG.18008.1_2 - 4.2 7.5 9.6 5.8 7.0 9.6 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain ANF_receptor PF01094.26 MSTRG.61764.1_3 - 2e-10 40.2 0.2 2.2e-10 40.0 0.2 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region BAR_3 PF16746.3 MSTRG.36160.1_2 - 2.5e-08 33.8 0.0 2.7e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 BAR domain of APPL family Dev_Cell_Death PF10539.7 MSTRG.36160.1_2 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Development and cell death domain ING PF12998.5 MSTRG.95336.1_2 - 3.9e-31 107.5 3.7 5.8e-31 106.9 3.7 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.27 MSTRG.95336.1_2 - 1.3e-05 24.8 8.0 1.3e-05 24.8 8.0 1.8 2 0 0 2 2 2 1 PHD-finger DUF4515 PF14988.4 MSTRG.95336.1_2 - 0.0071 16.1 3.0 0.011 15.5 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) Spc7 PF08317.9 MSTRG.95336.1_2 - 0.14 10.8 3.4 0.2 10.4 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein A_deaminase PF00962.20 MSTRG.124657.1_1 - 1.2e-16 60.8 0.1 1.3e-16 60.7 0.1 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dimer_Tnp_hAT PF05699.12 MSTRG.98524.1_1 - 1.9e-08 33.9 0.0 2.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DGF-1_4 PF11024.6 MSTRG.112141.1_1 - 3.6 8.4 35.9 1e+03 0.5 35.9 2.3 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Aerolysin PF01117.18 MSTRG.112141.1_1 - 4.1 6.4 14.3 4.7 6.2 14.3 1.1 1 0 0 1 1 1 0 Aerolysin toxin DGF-1_4 PF11024.6 MSTRG.112141.1_2 - 2 9.2 34.2 1.4 9.6 20.7 2.1 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Diphthami_syn_2 PF01902.15 MSTRG.126023.1_2 - 0.00028 20.3 0.0 0.00032 20.1 0.0 1.1 1 0 0 1 1 1 1 Diphthamide synthase Hum_adeno_E3A PF05393.9 MSTRG.20479.1_3 - 0.049 13.5 0.3 0.082 12.8 0.3 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein zf-C2H2 PF00096.24 MSTRG.138833.1_1 - 0.00033 20.8 5.8 0.00056 20.1 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.138833.1_1 - 0.31 11.9 4.2 0.61 10.9 4.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Pkinase PF00069.23 MSTRG.101893.1_2 - 1.2e-12 47.7 0.0 1.2e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.101893.1_2 - 2.6e-11 43.2 0.0 2.8e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kelch_3 PF13415.4 MSTRG.109720.1_3 - 4.6e-16 58.5 2.8 3e-07 30.4 0.0 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.4 MSTRG.109720.1_3 - 1.5e-12 47.0 1.1 3.2e-05 23.7 0.0 2.9 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.4 MSTRG.109720.1_3 - 1.3e-11 44.2 1.8 5.9e-05 22.8 0.3 2.9 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.23 MSTRG.109720.1_3 - 2.5e-08 33.3 0.1 0.01 15.3 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.4 MSTRG.109720.1_3 - 4.2e-08 33.0 0.1 0.0074 16.4 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.13 MSTRG.109720.1_3 - 6.6e-08 32.1 0.6 0.01 15.7 0.1 2.5 2 1 0 2 2 2 2 Kelch motif RVT_1 PF00078.25 MSTRG.40931.1_2 - 7.7e-07 28.7 0.1 8.3e-07 28.6 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM76 PF16046.3 MSTRG.81079.4_1 - 5.1e-37 127.7 25.5 5.9e-37 127.5 25.5 1.0 1 0 0 1 1 1 1 FAM76 protein MAP70 PF07058.9 MSTRG.81079.4_1 - 0.014 14.0 13.8 0.018 13.7 13.8 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Phage_GP20 PF06810.9 MSTRG.81079.4_1 - 0.023 14.3 5.7 0.046 13.4 5.7 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 MPS2 PF17060.3 MSTRG.81079.4_1 - 0.24 10.5 14.1 0.4 9.8 14.1 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF4887 PF16228.3 MSTRG.81079.4_1 - 2.6 7.8 24.0 1.1 9.0 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) DUF2570 PF10828.6 MSTRG.81079.4_1 - 3.1 7.6 15.4 13 5.6 9.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) OmpH PF03938.12 MSTRG.81079.4_1 - 8.6 6.2 14.5 16 5.3 14.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CRF PF00473.15 MSTRG.81079.4_1 - 9.4 6.3 8.7 1.2 9.2 4.0 2.0 2 0 0 2 2 2 0 Corticotropin-releasing factor family DUF2551 PF10826.6 MSTRG.75370.1_3 - 4.3 7.5 8.5 1.6e+02 2.5 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2551) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.34038.1_2 - 3.2e-07 30.4 0.6 5.8e-07 29.5 0.6 1.4 1 0 0 1 1 1 1 Transposase MSG PF02349.13 MSTRG.32515.1_2 - 0.0044 17.0 0.5 0.63 10.2 0.1 2.2 1 1 1 2 2 2 2 Major surface glycoprotein Chitin_bind_1 PF00187.17 MSTRG.32515.1_2 - 0.32 11.4 22.9 1.6e+04 -9.5 22.9 4.2 1 1 0 1 1 1 0 Chitin recognition protein DUF1774 PF08611.8 MSTRG.32515.1_2 - 2.3 8.5 4.7 1.6e+02 2.6 4.7 2.8 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1774) Rad21_Rec8_N PF04825.11 MSTRG.80519.1_3 - 4e-38 129.9 0.0 6.5e-38 129.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Myosin_head PF00063.19 MSTRG.18205.2_2 - 5.1e-247 821.3 2.5 5.9e-247 821.1 2.5 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.17 MSTRG.18205.2_2 - 1.4e-12 47.1 1.1 3e-12 46.0 1.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.4 MSTRG.18205.2_2 - 0.0066 16.6 0.1 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain PWI PF01480.15 MSTRG.18205.2_2 - 0.033 14.4 0.1 0.3 11.3 0.0 2.6 3 0 0 3 3 3 0 PWI domain Septin PF00735.16 MSTRG.18205.2_2 - 0.037 13.1 0.1 0.07 12.2 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.4 MSTRG.18205.2_2 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF3377 PF11857.6 MSTRG.101812.1_3 - 0.062 13.1 1.2 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) KIF1B PF12423.6 MSTRG.51793.1_2 - 6.2e-07 29.7 6.8 6.2e-07 29.7 6.8 2.0 2 0 0 2 2 2 1 Kinesin protein 1B FAM184 PF15665.3 MSTRG.51793.1_2 - 0.0083 15.8 1.8 0.0083 15.8 1.8 1.9 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B Med11 PF10280.7 MSTRG.51793.1_2 - 0.015 15.6 2.3 0.032 14.6 2.3 1.5 1 0 0 1 1 1 0 Mediator complex protein RGCC PF15151.4 MSTRG.51793.1_2 - 0.057 13.5 0.7 0.46 10.6 0.7 2.3 1 1 2 3 3 3 0 Response gene to complement 32 protein family UQ_con PF00179.24 MSTRG.111422.1_3 - 1.4e-47 160.8 0.1 1.7e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 MSTRG.111422.1_3 - 0.00015 21.4 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Macro PF01661.19 MSTRG.79822.1_1 - 1.3e-12 47.6 0.6 3.2e-08 33.5 0.1 2.2 2 0 0 2 2 2 2 Macro domain CoaE PF01121.18 MSTRG.33654.1_3 - 5.3e-20 71.7 0.0 7.7e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.4 MSTRG.33654.1_3 - 0.0078 16.6 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 MSTRG.33654.1_3 - 0.02 14.9 0.0 0.058 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.4 MSTRG.33654.1_3 - 0.16 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Abi PF02517.14 MSTRG.86951.1_1 - 0.28 11.5 1.5 0.4 11.0 1.5 1.2 1 0 0 1 1 1 0 CAAX protease self-immunity DDE_3 PF13358.4 MSTRG.80619.1_3 - 0.0068 16.0 0.0 0.0086 15.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ion_trans_2 PF07885.14 MSTRG.45071.1_2 - 2.1e-07 30.7 7.3 2.7e-07 30.3 5.8 1.8 1 1 1 2 2 2 1 Ion channel IRK PF01007.18 MSTRG.45071.1_2 - 0.014 14.2 1.6 0.015 14.1 1.6 1.1 1 0 0 1 1 1 0 Inward rectifier potassium channel DUF3915 PF13054.4 MSTRG.63749.1_3 - 0.037 13.9 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) WEMBL PF05701.9 MSTRG.132225.1_3 - 0.0032 16.1 1.3 0.0034 16.0 1.3 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light P-mevalo_kinase PF04275.12 MSTRG.132225.1_3 - 0.027 14.3 0.7 0.029 14.2 0.7 1.2 1 0 0 1 1 1 0 Phosphomevalonate kinase Myosin_head PF00063.19 MSTRG.47731.1_1 - 1.1e-30 106.5 2.0 1.1e-30 106.4 2.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) DUF2204 PF09970.7 MSTRG.47731.1_1 - 0.0075 15.8 0.6 0.025 14.1 0.1 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase of unknown function (DUF2204) Secretin_N_2 PF07655.11 MSTRG.17391.1_2 - 0.062 13.7 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Syntaxin-6_N PF09177.9 MSTRG.17391.1_2 - 0.17 12.4 2.7 0.7 10.4 0.2 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Arm PF00514.21 MSTRG.11514.1_2 - 0.0076 16.1 0.1 0.018 14.9 0.0 1.7 1 1 1 2 2 2 1 Armadillo/beta-catenin-like repeat DUF913 PF06025.10 MSTRG.11514.1_2 - 0.0077 15.1 0.1 0.009 14.9 0.1 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Roc PF08477.11 MSTRG.57350.1_3 - 6.2e-14 52.1 0.0 9.3e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 MSTRG.57350.1_3 - 3.2e-08 33.2 0.1 4.1e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.19 MSTRG.57350.1_3 - 0.015 14.6 0.1 0.023 14.0 0.1 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family DUF3677 PF12432.6 MSTRG.57350.1_3 - 0.091 12.9 2.1 0.28 11.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3677) PYRIN PF02758.14 MSTRG.22082.1_1 - 9.6e-06 25.6 1.2 4.6e-05 23.4 1.2 1.9 1 1 0 1 1 1 1 PAAD/DAPIN/Pyrin domain ALMS_motif PF15309.4 MSTRG.22468.1_2 - 0.015 15.6 0.2 0.016 15.5 0.2 1.1 1 0 0 1 1 1 0 ALMS motif EXS PF03124.12 MSTRG.15819.1_2 - 7e-25 87.9 0.2 7.3e-25 87.8 0.2 1.0 1 0 0 1 1 1 1 EXS family HTH_Tnp_Tc3_2 PF01498.16 MSTRG.45353.1_2 - 9.3e-13 48.1 0.8 1.4e-12 47.5 0.8 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.4 MSTRG.45353.1_2 - 0.0007 20.0 0.4 0.0011 19.5 0.4 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Arg_repressor PF01316.19 MSTRG.45353.1_2 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.45353.1_3 - 4.7e-05 23.4 0.0 7.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Transposase AC_N PF16214.3 MSTRG.69735.1_2 - 0.15 11.1 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Piwi PF02171.15 MSTRG.10681.1_2 - 2.6e-57 194.2 0.1 2.9e-57 194.1 0.1 1.0 1 0 0 1 1 1 1 Piwi domain Lep_receptor_Ig PF06328.9 MSTRG.51372.1_3 - 0.047 13.6 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Ig-like C2-type domain SinI PF08671.8 MSTRG.117683.1_3 - 1.2 8.8 8.8 6.7 6.5 0.5 3.0 3 0 0 3 3 3 0 Anti-repressor SinI bZIP_1 PF00170.19 MSTRG.112218.1_1 - 4.8e-13 48.9 11.0 7.4e-13 48.3 10.2 1.7 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.13 MSTRG.112218.1_1 - 6.3e-08 32.4 8.6 6.3e-08 32.4 8.6 1.7 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.15 MSTRG.112218.1_1 - 0.0002 21.6 8.4 0.0004 20.7 8.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor IncA PF04156.12 MSTRG.112218.1_1 - 0.086 12.5 0.9 0.18 11.4 0.9 1.4 1 0 0 1 1 1 0 IncA protein DUF2207 PF09972.7 MSTRG.112218.1_1 - 0.21 10.2 0.1 0.3 9.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DDE_3 PF13358.4 MSTRG.122442.1_2 - 0.049 13.2 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Tetraspannin PF00335.18 MSTRG.30841.1_1 - 0.024 14.3 0.1 0.029 14.1 0.1 1.1 1 0 0 1 1 1 0 Tetraspanin family RVT_1 PF00078.25 MSTRG.111684.1_1 - 2.8e-10 39.9 0.2 0.00016 21.2 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 MSTRG.111684.1_2 - 5.9e-06 25.8 0.0 0.031 13.7 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) EPL1 PF10513.7 MSTRG.12427.1_3 - 0.00012 22.3 0.8 0.00017 21.9 0.8 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like NINJA_B PF16136.3 MSTRG.84739.1_1 - 0.22 11.8 6.3 0.057 13.7 3.2 1.5 2 0 0 2 2 2 0 Putative nuclear localisation signal DUF1168 PF06658.10 MSTRG.84739.1_1 - 0.5 10.0 12.2 0.94 9.2 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF3808 PF10300.7 MSTRG.51999.1_1 - 3.3e-14 52.4 0.1 3.9e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Glutaredoxin2_C PF04399.11 MSTRG.51999.1_1 - 0.0092 15.7 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain TPR_8 PF13181.4 MSTRG.51999.1_1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-CCHC PF00098.21 MSTRG.105331.1_1 - 8.1e-05 22.4 0.3 0.00014 21.7 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.4 MSTRG.105331.1_1 - 0.011 15.4 1.0 0.017 14.8 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.6 MSTRG.105331.1_1 - 0.13 12.5 0.3 0.18 12.1 0.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G EF-hand_8 PF13833.4 MSTRG.106520.1_3 - 2.9e-18 65.2 8.3 1.7e-15 56.4 0.2 4.2 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.30 MSTRG.106520.1_3 - 5.4e-14 50.5 2.5 0.00034 19.8 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.4 MSTRG.106520.1_3 - 1.2e-12 46.5 3.1 0.00097 18.8 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 MSTRG.106520.1_3 - 1.1e-09 38.5 3.5 0.0013 19.0 0.1 3.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 MSTRG.106520.1_3 - 1.5e-08 33.7 2.1 0.33 10.4 0.0 4.5 4 0 0 4 4 4 3 EF hand Ion_trans PF00520.29 MSTRG.143318.1_3 - 0.0034 16.5 6.9 0.0064 15.6 6.9 1.5 1 1 0 1 1 1 1 Ion transport protein DUF807 PF05660.9 MSTRG.70845.1_3 - 0.11 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) Arrestin_N PF00339.27 MSTRG.67646.1_1 - 1.3e-17 64.1 0.1 1.9e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.13 MSTRG.67646.1_1 - 8.8e-05 21.5 0.1 0.00012 21.1 0.1 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.20 MSTRG.67646.1_1 - 0.00016 21.9 0.0 0.00067 19.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.8 MSTRG.67646.1_1 - 0.013 14.6 0.3 0.038 13.0 0.0 1.8 2 0 0 2 2 2 0 Rgp1 FCSD-flav_bind PF09242.9 MSTRG.67646.1_1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding EF-hand_1 PF00036.30 MSTRG.97196.1_2 - 0.002 17.4 0.8 0.002 17.4 0.8 1.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.4 MSTRG.97196.1_2 - 0.013 14.8 2.0 0.014 14.7 0.8 1.7 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.4 MSTRG.97196.1_2 - 0.015 15.0 0.2 0.044 13.6 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.4 MSTRG.97196.1_2 - 0.038 14.3 0.3 0.071 13.5 0.3 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.4 MSTRG.97196.1_2 - 0.06 13.0 0.3 0.097 12.3 0.3 1.4 1 0 0 1 1 1 0 EF-hand domain pair hSac2 PF12456.6 MSTRG.84773.1_2 - 6e-20 70.9 0.0 8.4e-20 70.5 0.0 1.2 1 0 0 1 1 1 1 Inositol phosphatase PBP_GOBP PF01395.20 MSTRG.84773.1_2 - 0.026 14.5 0.1 0.04 13.9 0.1 1.2 1 0 0 1 1 1 0 PBP/GOBP family SH3_9 PF14604.4 MSTRG.75546.1_3 - 0.00045 19.9 0.0 0.00056 19.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain Thioredoxin_7 PF13899.4 MSTRG.73681.1_2 - 0.0059 16.6 0.1 0.0076 16.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like ApoLp-III PF07464.9 MSTRG.73681.1_2 - 0.028 14.4 0.5 0.036 14.0 0.5 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Fez1 PF06818.13 MSTRG.73681.1_2 - 0.036 14.4 1.0 0.046 14.0 0.9 1.3 1 1 0 1 1 1 0 Fez1 Herpes_gI PF01688.15 MSTRG.73681.1_2 - 0.076 12.8 0.1 0.091 12.5 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I MFS_2 PF13347.4 MSTRG.95999.1_2 - 4.8e-05 21.9 0.1 5.4e-05 21.8 0.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Inhibitor_I78 PF11720.6 MSTRG.88793.1_1 - 0.029 14.3 0.4 20 5.2 0.0 3.1 1 1 3 4 4 4 0 Peptidase inhibitor I78 family FSIP2 PF15783.3 MSTRG.88793.1_1 - 0.57 7.9 1.2 13 3.4 0.2 2.2 1 1 1 2 2 2 0 Fibrous sheath-interacting protein 2 CTD PF12815.5 MSTRG.88793.1_2 - 0.098 13.1 6.3 0.22 12.0 6.3 1.7 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Mucin-like PF16058.3 MSTRG.88793.1_2 - 0.28 11.2 20.4 0.32 11.0 20.4 1.1 1 0 0 1 1 1 0 Mucin-like DUF2486 PF10667.7 MSTRG.88793.1_2 - 2.3 8.3 6.9 2.5 8.1 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) MSA-2c PF12238.6 MSTRG.88793.1_2 - 2.7 7.8 19.2 5 6.9 11.9 2.0 1 1 1 2 2 2 0 Merozoite surface antigen 2c Myosin_head PF00063.19 MSTRG.102721.1_3 - 2.5e-93 313.4 1.1 3e-93 313.1 1.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CD225 PF04505.10 MSTRG.89521.1_1 - 6e-12 45.4 0.3 1.9e-11 43.8 0.3 1.9 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.4 MSTRG.89521.1_1 - 0.0019 17.8 0.2 0.0041 16.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) CAF1C_H4-bd PF12265.6 MSTRG.115293.1_3 - 0.035 14.2 0.1 0.046 13.8 0.1 1.2 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Ins_beta PF03488.12 MSTRG.39745.1_2 - 0.011 15.5 1.0 0.02 14.8 1.0 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type VWA PF00092.26 MSTRG.39745.1_3 - 1.4e-33 116.5 0.5 1.8e-33 116.1 0.5 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.4 MSTRG.39745.1_3 - 7.5e-09 36.1 0.0 1.5e-08 35.1 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain MPDZ_u10 PF16667.3 MSTRG.93683.1_1 - 1.6e-14 54.4 7.6 1.9e-14 54.1 7.6 1.2 1 0 0 1 1 1 1 Unstructured region 10 on multiple PDZ protein WCCH PF03716.12 MSTRG.30888.1_1 - 0.087 12.4 3.4 0.17 11.4 3.4 1.5 1 0 0 1 1 1 0 WCCH motif NAD_binding_10 PF13460.4 MSTRG.43603.2_3 - 1.4e-41 142.3 0.0 1.7e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.11 MSTRG.43603.2_3 - 2.1e-11 43.7 0.0 2.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.19 MSTRG.43603.2_3 - 4.5e-08 32.7 0.0 8.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.15 MSTRG.43603.2_3 - 0.00027 21.3 0.0 0.00045 20.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.16 MSTRG.43603.2_3 - 0.0013 18.8 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.16 MSTRG.43603.2_3 - 0.0022 18.1 0.1 0.0044 17.1 0.1 1.5 1 1 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.15 MSTRG.43603.2_3 - 0.0023 17.0 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.18 MSTRG.43603.2_3 - 0.0025 17.8 0.1 0.0054 16.7 0.1 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.3 MSTRG.43603.2_3 - 0.0036 16.6 0.1 0.0055 16.0 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.23 MSTRG.43603.2_3 - 0.012 14.9 0.3 2.5 7.4 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.22 MSTRG.43603.2_3 - 0.013 15.8 0.0 0.047 14.0 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PPDK_N PF01326.17 MSTRG.43603.2_3 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 1 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF4083 PF13314.4 MSTRG.16861.1_2 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Thioredoxin PF00085.18 MSTRG.140624.1_2 - 2.9e-16 59.1 0.0 3.5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.9 MSTRG.140624.1_2 - 0.0022 17.8 0.0 0.0029 17.4 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.11 MSTRG.140624.1_2 - 0.0055 16.0 0.0 0.0061 15.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Spore_YhaL PF14147.4 MSTRG.119354.1_1 - 0.12 11.9 1.5 0.22 11.1 1.5 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL Astro_capsid_N PF03115.12 MSTRG.119354.1_1 - 0.24 10.0 2.3 0.25 10.0 2.3 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor LisH_2 PF16045.3 MSTRG.9614.1_1 - 0.093 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 LisH NIPSNAP PF07978.11 MSTRG.32352.1_3 - 0.00052 20.1 0.1 0.00085 19.4 0.1 1.4 1 0 0 1 1 1 1 NIPSNAP EGF_CA PF07645.13 MSTRG.26728.1_2 - 1.3e-06 28.4 3.6 1.3e-06 28.4 3.6 1.9 2 0 0 2 2 2 1 Calcium-binding EGF domain FXa_inhibition PF14670.4 MSTRG.26728.1_2 - 1.5e-06 28.2 2.4 2.9e-06 27.3 2.4 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.5 MSTRG.26728.1_2 - 6.8e-06 25.8 1.8 1.3e-05 24.9 1.8 1.5 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_3 PF12947.5 MSTRG.26728.1_2 - 0.0035 17.4 2.0 0.0036 17.3 1.0 1.6 2 0 0 2 2 2 1 EGF domain EGF PF00008.25 MSTRG.26728.1_2 - 0.0092 16.1 1.2 0.0092 16.1 1.2 1.7 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.5 MSTRG.26728.1_2 - 0.043 14.4 2.0 0.043 14.4 2.0 1.9 2 0 0 2 2 2 0 Human growth factor-like EGF TMEM252 PF15664.3 MSTRG.32482.1_1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF1077 PF06417.10 MSTRG.38545.1_2 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DDE_3 PF13358.4 MSTRG.71952.1_3 - 8.2e-05 22.3 0.1 0.00011 21.9 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_primase_S PF01896.17 MSTRG.42245.1_2 - 0.0014 18.7 0.2 0.0019 18.2 0.2 1.2 1 0 0 1 1 1 1 DNA primase small subunit tRNA_anti-codon PF01336.23 MSTRG.109775.1_3 - 1.5e-12 47.2 0.0 2.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2 PF00152.18 MSTRG.109775.1_3 - 4.2e-11 42.4 1.1 4.9e-11 42.1 0.2 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF1565 PF07602.9 MSTRG.109775.1_3 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) DEAD PF00270.27 MSTRG.37437.1_1 - 2.2e-45 154.4 0.5 3.3e-45 153.9 0.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 MSTRG.37437.1_1 - 1.7e-31 108.7 0.4 2.3e-30 105.1 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.13 MSTRG.37437.1_1 - 8.2e-07 29.0 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.4 MSTRG.37437.1_1 - 0.00036 20.2 0.1 0.00057 19.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.4 MSTRG.37437.1_1 - 0.0041 17.3 0.6 0.008 16.4 0.1 1.7 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.4 MSTRG.37437.1_1 - 0.011 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.12 MSTRG.37437.1_1 - 0.047 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Helicase SNF2_N PF00176.21 MSTRG.37437.1_1 - 0.099 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Flavi_DEAD PF07652.12 MSTRG.37437.1_1 - 0.1 12.4 0.1 0.36 10.7 0.1 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.19 MSTRG.37437.1_1 - 0.11 11.8 0.2 0.17 11.3 0.2 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MAP1B_neuraxin PF00414.15 MSTRG.97423.1_3 - 0.32 10.4 2.1 19 4.8 0.2 2.4 2 0 0 2 2 2 0 Neuraxin and MAP1B repeat Pkinase PF00069.23 MSTRG.34001.1_3 - 7.7e-37 126.9 2.4 9.1e-37 126.7 2.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.34001.1_3 - 3.3e-23 82.1 1.8 4e-23 81.9 1.8 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sarcoglycan_2 PF05510.11 MSTRG.35185.1_3 - 4e-21 75.1 0.7 3.4e-20 72.1 0.7 1.9 1 1 0 1 1 1 1 Sarcoglycan alpha/epsilon PP-binding_2 PF14573.4 MSTRG.35185.1_3 - 0.089 12.9 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Acyl-carrier PCRF PF03462.16 MSTRG.50431.8_1 - 0.02 14.7 0.7 54 3.4 0.0 3.5 4 0 0 4 4 4 0 PCRF domain Nebulin PF00880.16 MSTRG.50431.8_3 - 2e-103 337.4 122.8 1.3e-06 28.1 2.2 28.9 31 0 0 31 31 31 23 Nebulin repeat Chorion_2 PF03964.13 MSTRG.50431.8_3 - 6.3e-06 26.8 16.6 0.55 11.0 0.1 5.4 6 0 0 6 6 6 4 Chorion family 2 DUF2847 PF11009.6 MSTRG.50431.8_3 - 0.04 13.7 0.1 1.7 8.4 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) OST-HTH PF12872.5 MSTRG.50431.8_3 - 0.064 13.0 0.0 18 5.2 0.0 3.7 3 0 0 3 3 3 0 OST-HTH/LOTUS domain DUF2799 PF10973.6 MSTRG.50431.8_3 - 0.16 12.2 13.8 12 6.3 0.1 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2799) Arginosuc_synth PF00764.17 MSTRG.27546.1_3 - 7.3e-165 548.8 0.0 8.5e-165 548.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.11 MSTRG.27546.1_3 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.14 MSTRG.27546.1_3 - 0.017 13.8 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.19 MSTRG.27546.1_3 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Thiolase_C PF02803.16 MSTRG.95871.1_1 - 1.9e-15 56.5 0.5 2.3e-15 56.2 0.5 1.1 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF997 PF06196.10 MSTRG.13193.1_2 - 0.0037 17.1 1.4 0.0055 16.6 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF997) Flot PF15975.3 MSTRG.96434.1_1 - 6.7e-05 22.9 15.0 7.9e-05 22.7 8.7 2.1 1 1 1 2 2 2 2 Flotillin CNOT1_CAF1_bind PF16415.3 MSTRG.10259.1_3 - 1.4e-31 109.5 3.1 1.7e-31 109.2 3.1 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain TLV_coat PF00429.17 MSTRG.125025.1_3 - 3e-05 22.8 0.0 3.4e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) EGF_CA PF07645.13 MSTRG.24513.1_3 - 5.4e-24 84.0 21.9 8.8e-10 38.5 2.4 3.2 3 0 0 3 3 3 3 Calcium-binding EGF domain cEGF PF12662.5 MSTRG.24513.1_3 - 5.4e-18 64.5 4.2 4e-09 36.1 0.2 3.8 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_3 PF12947.5 MSTRG.24513.1_3 - 1.2e-11 44.5 22.2 8.1e-08 32.2 3.7 4.0 3 2 1 4 4 4 2 EGF domain EGF_MSP1_1 PF12946.5 MSTRG.24513.1_3 - 1.4e-08 34.5 10.8 8.4e-05 22.4 3.8 2.9 2 1 0 2 2 2 2 MSP1 EGF domain 1 FXa_inhibition PF14670.4 MSTRG.24513.1_3 - 4.2e-08 33.2 25.0 0.0038 17.4 7.8 4.3 3 1 1 4 4 4 2 Coagulation Factor Xa inhibitory site EGF PF00008.25 MSTRG.24513.1_3 - 1.5e-06 28.2 22.3 4.8e-05 23.4 0.9 4.3 3 2 1 4 4 4 2 EGF-like domain hEGF PF12661.5 MSTRG.24513.1_3 - 1.8e-05 25.1 25.9 0.0005 20.5 2.1 4.4 4 0 0 4 4 4 2 Human growth factor-like EGF Tme5_EGF_like PF09064.8 MSTRG.24513.1_3 - 7.4 6.4 18.0 0.085 12.6 2.1 3.2 3 1 0 3 3 3 0 Thrombomodulin like fifth domain, EGF-like Sulfotransfer_1 PF00685.25 MSTRG.54355.2_1 - 1.1e-05 25.0 0.1 0.00086 18.7 0.1 2.2 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_1 PF00685.25 MSTRG.54355.2_2 - 0.0074 15.7 0.2 0.01 15.2 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.50256.1_3 - 3.3e-08 33.5 3.9 3.3e-08 33.5 3.9 2.5 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.4 MSTRG.50256.1_3 - 9.6e-05 21.9 0.2 0.00057 19.5 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.4 MSTRG.50256.1_3 - 0.0029 17.6 0.0 0.024 14.6 0.0 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.13 MSTRG.50256.1_3 - 0.0049 16.8 2.1 0.078 12.9 0.0 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase PAX PF00292.16 MSTRG.50256.1_3 - 0.029 14.1 0.6 0.043 13.6 0.1 1.5 2 0 0 2 2 2 0 'Paired box' domain TrmB PF01978.17 MSTRG.50256.1_3 - 0.043 13.6 0.4 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_32 PF13565.4 MSTRG.50256.1_3 - 0.076 13.5 0.2 0.26 11.8 0.2 1.9 1 1 0 1 1 1 0 Homeodomain-like domain MarR_2 PF12802.5 MSTRG.50256.1_3 - 0.15 11.8 0.1 0.35 10.7 0.0 1.6 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.4 MSTRG.70697.1_3 - 6e-05 22.6 0.1 7.4e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.70697.1_3 - 0.00043 19.9 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Ribosomal_S13_N PF08069.10 MSTRG.70697.1_3 - 0.0012 18.7 0.6 0.014 15.3 0.1 2.1 1 1 1 2 2 2 1 Ribosomal S13/S15 N-terminal domain PAX PF00292.16 MSTRG.70697.1_3 - 0.025 14.3 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain DUF4269 PF14091.4 MSTRG.70697.1_3 - 0.033 14.3 0.1 0.037 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) HTH_Tnp_ISL3 PF13542.4 MSTRG.70697.1_3 - 0.073 12.4 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.4 MSTRG.70697.1_3 - 0.15 12.0 0.7 8.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix BRICHOS PF04089.12 MSTRG.129931.1_1 - 0.064 13.2 0.1 5.6 7.0 0.0 2.1 1 1 1 2 2 2 0 BRICHOS domain Prp19 PF08606.9 MSTRG.129931.1_3 - 0.019 14.8 0.5 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 Prp19/Pso4-like HTH_23 PF13384.4 MSTRG.93450.1_2 - 7.9e-05 22.2 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.16 MSTRG.93450.1_2 - 0.028 14.2 0.1 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 'Paired box' domain MarR_2 PF12802.5 MSTRG.93450.1_2 - 0.066 13.0 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.4 MSTRG.93450.1_2 - 0.086 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_35 PF13693.4 MSTRG.93450.1_2 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.17 MSTRG.93450.1_2 - 0.16 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.4 MSTRG.93450.1_2 - 0.17 11.8 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix BTB PF00651.29 MSTRG.5992.1_1 - 2.7e-11 43.5 0.0 4.1e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain PEGSRP PF07623.9 MSTRG.45646.1_1 - 1.7 8.4 7.2 0.32 10.7 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) Rib_recp_KP_reg PF05104.10 MSTRG.81439.1_1 - 0.47 11.4 0.9 0.57 11.1 0.9 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Reticulon PF02453.15 MSTRG.80877.1_2 - 1.2e-44 151.8 5.9 2.2e-44 151.0 5.9 1.4 1 0 0 1 1 1 1 Reticulon SH2 PF00017.22 MSTRG.41126.1_2 - 1.5e-17 63.3 0.1 2.1e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 SH2 domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.31807.1_1 - 0.0011 19.1 1.0 0.0016 18.5 1.0 1.2 1 0 0 1 1 1 1 Transposase DUF601 PF04642.10 MSTRG.116727.1_3 - 0.024 14.0 3.9 0.024 14.0 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF601 PDZ PF00595.22 MSTRG.136509.1_1 - 2.2e-16 59.8 0.2 5.3e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 MSTRG.136509.1_1 - 4.7e-08 33.1 0.0 0.00011 22.3 0.0 2.1 1 1 1 2 2 2 2 PDZ domain DUF4695 PF15766.3 MSTRG.27173.1_1 - 0.00031 20.8 3.7 0.00043 20.3 3.7 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4695) Toxin_YhaV PF11663.6 MSTRG.100085.1_3 - 0.11 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system DUF1031 PF06275.9 MSTRG.109802.1_2 - 0.048 13.8 0.2 0.082 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Paf1 PF03985.11 MSTRG.45225.1_3 - 3.2e-83 280.0 7.6 3.8e-83 279.7 7.6 1.0 1 0 0 1 1 1 1 Paf1 COesterase PF00135.26 MSTRG.45225.1_3 - 0.038 12.8 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family PI3K_P85_iSH2 PF16454.3 MSTRG.121491.1_3 - 0.003 17.0 2.6 0.003 17.0 2.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.9 MSTRG.121491.1_3 - 0.0069 15.2 2.3 0.0069 15.2 2.3 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF5082 PF16888.3 MSTRG.121491.1_3 - 0.0069 16.6 1.3 0.0089 16.2 1.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) ApoL PF05461.9 MSTRG.121491.1_3 - 0.024 13.9 0.8 0.025 13.8 0.8 1.0 1 0 0 1 1 1 0 Apolipoprotein L Spc24 PF08286.9 MSTRG.121491.1_3 - 0.058 13.5 2.8 0.065 13.3 2.8 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4718 PF15842.3 MSTRG.121491.1_3 - 0.059 13.0 0.8 0.063 12.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Rad21_Rec8_N PF04825.11 MSTRG.121491.1_3 - 0.11 12.6 0.7 0.14 12.2 0.7 1.1 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein IncA PF04156.12 MSTRG.121491.1_3 - 0.12 12.0 3.7 0.13 11.9 3.7 1.0 1 0 0 1 1 1 0 IncA protein P66_CC PF16563.3 MSTRG.121491.1_3 - 0.92 9.0 9.8 4.7 6.8 9.7 2.1 1 1 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Trimer_CC PF08954.9 MSTRG.121491.1_3 - 1.3 8.5 9.1 3.7 7.0 5.8 2.4 1 1 1 2 2 2 0 Trimerisation motif FOXP-CC PF16159.3 MSTRG.138341.1_1 - 0.041 14.4 0.1 0.041 14.4 0.1 1.8 2 0 0 2 2 2 0 FOXP coiled-coil domain Pkinase PF00069.23 MSTRG.124343.1_3 - 0.0075 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DnaJ_C PF01556.16 MSTRG.47495.2_2 - 2.1e-39 134.9 0.1 2.8e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 MSTRG.47495.2_2 - 1.1e-25 89.4 0.4 2e-25 88.6 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.17 MSTRG.47495.2_2 - 1.7e-10 41.0 17.9 2.9e-10 40.3 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain RVT_3 PF13456.4 MSTRG.57133.1_2 - 0.04 13.5 0.1 0.074 12.6 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase-like An_peroxidase PF03098.13 MSTRG.69319.1_1 - 1.9e-52 178.4 0.1 3.4e-46 157.8 0.1 2.4 1 1 1 2 2 2 2 Animal haem peroxidase zf-H2C2_2 PF13465.4 MSTRG.36335.1_1 - 1.8e-11 43.8 14.9 4.1e-09 36.4 3.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.4 MSTRG.36335.1_1 - 2.4e-11 43.1 3.4 2.2e-05 24.0 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.24 MSTRG.36335.1_1 - 8.3e-10 38.4 13.0 4e-06 26.9 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.36335.1_1 - 1.9e-08 34.3 8.3 0.00024 21.5 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.3 MSTRG.36335.1_1 - 0.00047 19.7 0.2 0.0013 18.4 0.2 1.6 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-Di19 PF05605.10 MSTRG.36335.1_1 - 0.014 15.5 1.9 0.031 14.4 1.9 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.3 MSTRG.36335.1_1 - 0.019 15.1 0.1 0.035 14.3 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.4 MSTRG.36335.1_1 - 0.023 14.5 8.8 1.1 9.2 3.3 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-TRAF PF02176.16 MSTRG.36335.1_1 - 0.026 15.1 2.2 0.043 14.4 2.2 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2HE PF16278.3 MSTRG.36335.1_1 - 0.061 13.7 5.1 1.5 9.2 0.8 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_7 PF15269.4 MSTRG.36335.1_1 - 0.34 10.9 3.4 5.3 7.1 0.2 2.4 1 1 1 2 2 2 0 Zinc-finger DUF4764 PF15961.3 MSTRG.36335.1_1 - 2.9 6.3 6.9 0.25 9.9 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) zf-RING_UBOX PF13445.4 MSTRG.17089.1_2 - 1.3e-07 31.3 9.9 1.7e-07 31.0 9.9 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 MSTRG.17089.1_2 - 4.5e-06 26.4 6.5 5.8e-06 26.0 6.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.4 MSTRG.17089.1_2 - 6.6e-06 26.2 9.1 8.3e-06 25.8 9.1 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.23 MSTRG.17089.1_2 - 4e-05 23.3 9.5 6.7e-05 22.6 9.6 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 MSTRG.17089.1_2 - 0.00049 19.7 11.6 0.001 18.7 11.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 MSTRG.17089.1_2 - 0.001 18.7 8.2 0.013 15.2 2.9 2.2 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.4 MSTRG.17089.1_2 - 0.012 15.6 11.0 0.045 13.8 11.1 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.3 MSTRG.17089.1_2 - 0.049 13.2 10.7 0.073 12.7 10.7 1.3 1 0 0 1 1 1 0 RING-like zinc finger CENP-K PF11802.6 MSTRG.112249.1_2 - 0.0031 17.0 0.4 0.0043 16.5 0.4 1.2 1 0 0 1 1 1 1 Centromere-associated protein K Mucin PF01456.15 MSTRG.30688.1_2 - 0.84 9.5 5.9 0.93 9.3 5.9 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Actin PF00022.17 MSTRG.41884.1_1 - 1.4e-23 83.1 0.0 1.2e-22 80.0 0.0 1.9 1 1 0 1 1 1 1 Actin AMP-binding PF00501.26 MSTRG.25574.1_3 - 0.00041 18.9 0.0 0.00043 18.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme TRAPP PF04051.14 MSTRG.113489.1_1 - 9.5e-38 129.1 0.0 1.3e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF645 PF04875.10 MSTRG.31185.1_2 - 0.078 12.9 1.3 0.21 11.5 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF645 DUF1031 PF06275.9 MSTRG.143142.1_2 - 0.013 15.6 0.1 0.019 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) zf-C3HC4_3 PF13920.4 MSTRG.143819.1_1 - 7.8e-11 41.5 5.4 1.1e-10 41.0 5.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 MSTRG.143819.1_1 - 8.4e-10 38.6 10.2 1.1e-09 38.2 10.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.23 MSTRG.143819.1_1 - 1.2e-09 37.7 7.8 1.6e-09 37.3 7.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 MSTRG.143819.1_1 - 7e-09 35.3 9.0 1e-08 34.7 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 MSTRG.143819.1_1 - 4.6e-07 29.5 7.1 6.4e-07 29.0 7.1 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 MSTRG.143819.1_1 - 1e-06 28.5 4.0 1e-06 28.5 4.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 MSTRG.143819.1_1 - 1.6e-06 27.9 6.5 2.3e-06 27.4 6.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.5 MSTRG.143819.1_1 - 2.9e-05 24.1 8.1 4.7e-05 23.4 8.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.5 MSTRG.143819.1_1 - 0.00013 21.9 2.9 0.00018 21.3 2.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.9 MSTRG.143819.1_1 - 0.00032 20.5 2.4 0.00047 20.0 2.4 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.4 MSTRG.143819.1_1 - 0.0014 18.6 8.0 0.002 18.1 8.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.10 MSTRG.143819.1_1 - 0.01 15.1 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-UDP PF14569.4 MSTRG.143819.1_1 - 0.026 14.5 1.4 0.053 13.5 1.4 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.4 MSTRG.143819.1_1 - 0.037 13.6 5.6 0.071 12.7 5.6 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.19 MSTRG.143819.1_1 - 0.36 11.0 7.0 21 5.3 8.0 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn_ribbon_17 PF17120.3 MSTRG.143819.1_1 - 0.45 10.0 5.5 0.7 9.4 5.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.9 MSTRG.143819.1_1 - 1 9.4 4.4 2.5 8.1 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) DDE_3 PF13358.4 MSTRG.51522.1_2 - 3.7e-09 36.3 0.1 6.2e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.25 MSTRG.13789.1_1 - 1.8e-07 30.8 0.1 4.7e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) I-set PF07679.14 MSTRG.86589.1_1 - 2.7e-15 56.1 0.0 3.3e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.86589.1_1 - 2.8e-12 46.9 0.0 3.9e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.86589.1_1 - 6.1e-09 36.0 0.0 7.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.86589.1_1 - 1.5e-07 31.4 0.0 2.5e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 MSTRG.86589.1_1 - 0.00016 21.5 0.0 0.00024 21.0 0.0 1.4 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.15 MSTRG.86589.1_1 - 0.0007 19.6 0.1 0.098 12.7 0.1 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.3 MSTRG.86589.1_1 - 0.0018 18.5 0.0 0.004 17.4 0.0 1.5 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.13 MSTRG.86589.1_1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.5 1 1 1 2 2 2 0 Adenovirus E3 region protein CR1 DOR PF14839.4 MSTRG.52695.1_1 - 0.14 12.0 1.3 0.2 11.4 1.3 1.2 1 0 0 1 1 1 0 DOR family GvpG PF05120.10 MSTRG.52931.1_1 - 0.078 12.9 3.0 0.16 11.9 3.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G zf-H2C2_2 PF13465.4 MSTRG.18168.1_3 - 1.8e-18 65.9 24.2 9.8e-10 38.3 2.1 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.18168.1_3 - 3.1e-16 58.7 22.6 6.6e-06 26.2 4.7 3.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.18168.1_3 - 9.3e-12 44.6 19.6 0.00051 20.5 1.9 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.18168.1_3 - 1.9e-08 33.9 16.4 0.0055 16.5 0.3 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.3 MSTRG.18168.1_3 - 8.2e-06 25.3 16.4 0.00045 19.8 3.7 2.8 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.6 MSTRG.18168.1_3 - 8.2e-06 25.9 8.5 0.0077 16.4 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.3 MSTRG.18168.1_3 - 1.5e-05 25.2 14.3 0.014 15.7 0.4 3.1 2 1 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.8 MSTRG.18168.1_3 - 4.9e-05 23.2 5.6 0.072 13.1 0.1 3.1 3 0 0 3 3 3 2 Zinc ribbon domain zf-LYAR PF08790.9 MSTRG.18168.1_3 - 8.6e-05 22.2 9.5 0.63 9.9 0.1 3.2 3 0 0 3 3 3 3 LYAR-type C2HC zinc finger zf-met PF12874.5 MSTRG.18168.1_3 - 0.00019 21.5 15.2 0.038 14.2 2.1 3.1 3 0 0 3 3 3 3 Zinc-finger of C2H2 type Rpr2 PF04032.14 MSTRG.18168.1_3 - 0.0043 17.2 3.3 0.23 11.7 0.1 2.1 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-TFIIB PF13453.4 MSTRG.18168.1_3 - 0.0069 15.6 1.5 2 7.7 0.2 2.3 1 1 1 2 2 2 2 Transcription factor zinc-finger MTHFR_C PF12225.6 MSTRG.18168.1_3 - 0.015 14.8 2.6 0.043 13.3 0.3 2.1 1 1 1 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal MqsA_antitoxin PF15731.3 MSTRG.18168.1_3 - 0.016 15.2 1.6 1.3 9.0 0.3 2.1 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-trcl PF13451.4 MSTRG.18168.1_3 - 0.018 14.8 1.6 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain Fer4_10 PF13237.4 MSTRG.18168.1_3 - 0.019 14.9 0.9 0.22 11.5 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.5 MSTRG.18168.1_3 - 0.025 14.5 2.6 0.16 12.0 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain zf-ribbon_3 PF13248.4 MSTRG.18168.1_3 - 0.03 13.6 6.5 1.6 8.1 0.6 2.9 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.5 MSTRG.18168.1_3 - 0.033 14.1 5.0 0.74 9.8 5.0 2.1 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.20 MSTRG.18168.1_3 - 0.045 13.5 7.7 0.76 9.6 0.2 2.6 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YhfH PF14149.4 MSTRG.18168.1_3 - 0.055 13.3 3.7 3.8 7.5 0.0 2.8 3 0 0 3 3 3 0 YhfH-like protein zf-C2H2_2 PF12756.5 MSTRG.18168.1_3 - 0.11 12.8 8.6 2.1 8.6 2.3 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) PknG_rubred PF16919.3 MSTRG.18168.1_3 - 0.13 12.2 2.1 0.19 11.7 1.7 1.4 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain SprT-like PF10263.7 MSTRG.18168.1_3 - 0.14 11.8 6.6 0.13 12.0 5.1 1.7 1 1 1 2 2 2 0 SprT-like family Nudix_N_2 PF14803.4 MSTRG.18168.1_3 - 0.15 11.9 7.4 0.78 9.6 0.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal zf-C2HC_2 PF13913.4 MSTRG.18168.1_3 - 0.36 10.7 0.4 0.36 10.7 0.4 3.4 3 1 0 3 3 3 0 zinc-finger of a C2HC-type Fer4 PF00037.25 MSTRG.18168.1_3 - 0.56 10.0 4.0 1.1 9.1 0.8 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.5 MSTRG.18168.1_3 - 0.61 10.1 3.7 1.4 9.0 0.7 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain XPA_N PF01286.16 MSTRG.18168.1_3 - 1 9.3 5.6 16 5.5 0.3 2.9 3 0 0 3 3 3 0 XPA protein N-terminal FYVE PF01363.19 MSTRG.18168.1_3 - 1.6 8.8 10.9 7.2 6.7 4.3 2.2 1 1 1 2 2 2 0 FYVE zinc finger YEATS PF03366.14 MSTRG.75846.1_1 - 1.8e-05 24.5 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 YEATS family DUF3787 PF12655.5 MSTRG.141510.1_1 - 0.07 12.9 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) ELL PF10390.7 MSTRG.103478.1_3 - 9.1e-34 117.1 1.2 9.1e-34 117.1 1.2 1.7 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.11 MSTRG.103478.1_3 - 5.8e-12 46.1 0.2 5.8e-12 46.1 0.2 2.7 3 0 0 3 3 3 1 Occludin homology domain DUF4351 PF14261.4 MSTRG.103478.1_3 - 0.061 13.3 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) DUF106 PF01956.14 MSTRG.580.1_1 - 6.9e-10 38.8 0.2 7.5e-10 38.7 0.2 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 zf-RING_2 PF13639.4 MSTRG.118261.1_2 - 5e-13 49.0 9.3 5e-13 49.0 9.3 1.5 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.3 MSTRG.118261.1_2 - 1.1e-09 37.7 5.2 2e-09 36.9 5.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.5 MSTRG.118261.1_2 - 6.5e-09 35.8 9.6 3.3e-08 33.6 9.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.4 MSTRG.118261.1_2 - 1.7e-08 34.0 9.2 3.4e-08 33.1 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 MSTRG.118261.1_2 - 3.8e-07 29.7 8.3 6.7e-07 28.9 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 MSTRG.118261.1_2 - 8.4e-07 28.8 2.3 8.4e-07 28.8 2.3 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 MSTRG.118261.1_2 - 8.7e-07 28.7 7.6 1.5e-06 27.9 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 MSTRG.118261.1_2 - 4.5e-05 23.1 9.5 6.8e-05 22.5 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.4 MSTRG.118261.1_2 - 7.6e-05 22.4 6.1 8.3e-05 22.3 0.9 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.5 MSTRG.118261.1_2 - 0.00035 20.4 6.0 0.00078 19.3 6.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.4 MSTRG.118261.1_2 - 0.036 13.8 10.7 0.067 12.9 10.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.3 MSTRG.118261.1_2 - 0.044 13.3 7.3 0.071 12.6 7.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.5 MSTRG.118261.1_2 - 0.065 13.2 8.8 0.12 12.4 8.8 1.4 1 0 0 1 1 1 0 RING-variant domain Zf_RING PF16744.3 MSTRG.118261.1_2 - 0.19 11.7 4.1 0.34 10.9 4.1 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger FANCL_C PF11793.6 MSTRG.118261.1_2 - 1.8 8.6 12.5 48 4.1 12.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Xin PF08043.10 MSTRG.48254.1_3 - 0.15 11.6 0.3 0.15 11.6 0.3 2.4 4 0 0 4 4 4 0 Xin repeat Nop16 PF09420.8 MSTRG.129480.1_2 - 1.6e-18 67.3 7.1 8.2e-13 48.7 0.4 2.2 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Cadherin PF00028.15 MSTRG.204.2_1 - 1.1e-48 163.5 12.1 2e-16 60.1 0.3 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.10 MSTRG.204.2_1 - 2.9e-06 26.9 0.1 0.3 10.8 0.0 4.4 4 1 0 4 4 4 2 Cadherin-like Cadherin_pro PF08758.9 MSTRG.204.2_1 - 2.9e-05 24.0 0.8 0.27 11.3 0.1 3.6 3 0 0 3 3 3 2 Cadherin prodomain like Cadherin_3 PF16184.3 MSTRG.204.2_1 - 0.00042 20.2 10.1 0.5 10.3 0.1 4.4 4 0 0 4 4 4 3 Cadherin-like PRE_C2HC PF07530.9 MSTRG.37929.1_1 - 0.29 11.1 3.5 2.5 8.2 0.2 2.7 1 1 2 3 3 3 0 Associated with zinc fingers RTP1_C2 PF10304.7 MSTRG.37929.1_1 - 2.3 7.8 16.5 2.8 7.6 0.4 4.0 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 2 Antimicrobial14 PF08109.9 MSTRG.37929.1_3 - 7.9 6.5 7.4 25 4.9 0.3 3.2 3 0 0 3 3 3 0 Lactocin 705 family GF_recep_IV PF14843.4 MSTRG.30581.1_3 - 3.3e-24 85.0 14.3 3.6e-24 84.9 14.3 1.0 1 0 0 1 1 1 1 Growth factor receptor domain IV Furin-like PF00757.18 MSTRG.30581.1_3 - 0.0012 18.6 12.6 0.006 16.3 5.8 2.0 1 1 1 2 2 2 2 Furin-like cysteine rich region zf-B_box PF00643.22 MSTRG.34627.1_3 - 1e-08 35.0 17.8 9.3e-08 32.0 4.3 2.3 2 0 0 2 2 2 2 B-box zinc finger DUF2180 PF09947.7 MSTRG.34627.1_3 - 0.31 10.9 7.1 4.7 7.1 7.0 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-UBP PF02148.17 MSTRG.34627.1_3 - 0.45 10.8 12.7 1.2 9.3 12.7 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Transp_Tc5_C PF04236.13 MSTRG.34627.1_3 - 1.7 8.9 11.3 0.49 10.7 3.4 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-4CXXC_R1 PF10497.7 MSTRG.34627.1_3 - 9.1 6.5 14.0 1.1e+02 3.0 14.0 2.0 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 HAUS6_N PF14661.4 MSTRG.20109.1_3 - 2.5e-27 95.8 0.0 2.6e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DDE_3 PF13358.4 MSTRG.18125.1_1 - 0.035 13.7 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.4 MSTRG.18125.1_3 - 2.9e-05 23.7 0.3 0.00015 21.5 0.3 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease UCH PF00443.27 MSTRG.58710.1_2 - 9.1e-22 77.6 0.2 1.1e-21 77.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 MSTRG.58710.1_2 - 0.0051 16.4 0.1 0.0064 16.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Vta1 PF04652.14 MSTRG.58710.1_2 - 0.077 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Vta1 like SlyX PF04102.10 MSTRG.58710.1_2 - 0.11 13.0 1.2 1.5 9.4 0.1 2.5 2 0 0 2 2 2 0 SlyX zf-AN1 PF01428.14 MSTRG.38322.1_2 - 0.87 9.7 4.1 0.34 11.0 1.7 1.6 2 0 0 2 2 2 0 AN1-like Zinc finger NTS PF15447.4 MSTRG.91046.1_1 - 0.012 15.9 0.1 0.012 15.9 0.1 1.7 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 FOXP-CC PF16159.3 MSTRG.91046.1_1 - 1 9.9 3.5 0.9 10.1 2.0 1.6 2 0 0 2 2 2 0 FOXP coiled-coil domain Yip1 PF04893.15 MSTRG.90488.1_2 - 5.1e-17 62.0 10.3 5.1e-17 62.0 10.3 2.8 2 2 0 2 2 2 1 Yip1 domain Fringe PF02434.14 MSTRG.32171.1_3 - 7.5e-26 90.9 0.1 8.4e-26 90.8 0.1 1.0 1 0 0 1 1 1 1 Fringe-like PTN13_u3 PF16599.3 MSTRG.123125.1_2 - 1e-40 139.8 5.8 1.2e-40 139.5 5.8 1.1 1 0 0 1 1 1 1 Unstructured linker region on PTN13 protein between PDZ Fer4_17 PF13534.4 MSTRG.119329.1_1 - 7.6e-06 26.2 0.8 1e-05 25.9 0.8 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.4 MSTRG.119329.1_1 - 7.9e-05 22.9 16.1 0.0033 17.7 4.7 1.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.4 MSTRG.119329.1_1 - 0.00079 19.3 0.2 0.00082 19.3 0.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Tetraspannin PF00335.18 MSTRG.36835.1_3 - 3.5e-10 39.9 3.5 3.8e-10 39.8 3.5 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2206 PF09971.7 MSTRG.36835.1_3 - 0.28 9.8 2.9 0.31 9.6 2.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Peptidase_A22B PF04258.11 MSTRG.100274.1_3 - 1.3e-11 44.4 0.2 1.6e-11 44.1 0.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Plexin_cytopl PF08337.10 MSTRG.87927.1_2 - 6.3e-70 236.3 0.5 6.9e-70 236.1 0.5 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain DUF1031 PF06275.9 MSTRG.68462.1_2 - 0.019 15.0 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) RRM_1 PF00076.20 MSTRG.106447.1_3 - 7.4e-42 140.9 0.6 6.1e-15 54.7 0.1 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 MSTRG.106447.1_3 - 2.7e-08 33.7 0.1 0.047 13.7 0.0 4.3 2 2 1 3 3 3 3 RNA recognition motif RRM_5 PF13893.4 MSTRG.106447.1_3 - 6.6e-05 22.4 0.0 0.00015 21.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 MSTRG.106447.1_3 - 0.005 16.6 0.1 15 5.5 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.6 MSTRG.106447.1_3 - 0.011 15.7 0.0 1.6 8.7 0.0 3.4 3 0 0 3 3 3 0 Limkain b1 RRM_occluded PF16842.3 MSTRG.106447.1_3 - 0.025 14.3 0.0 0.29 10.9 0.0 2.5 3 0 0 3 3 3 0 Occluded RNA-recognition motif Sema PF01403.17 MSTRG.17795.1_1 - 1.5e-38 132.6 0.0 1.6e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Sema domain Peptidase_M17 PF00883.19 MSTRG.107297.1_1 - 7.2e-12 45.1 0.0 8.6e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain RVT_1 PF00078.25 MSTRG.80497.1_3 - 1.3e-11 44.3 0.0 1.4e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rdx PF10262.7 MSTRG.124936.1_1 - 2.8e-08 33.7 0.0 5.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Rdx family DUF2190 PF09956.7 MSTRG.3622.1_1 - 0.0045 17.1 0.2 21 5.3 0.0 3.1 1 1 2 3 3 3 3 Uncharacterized conserved protein (DUF2190) HMG_box PF00505.17 MSTRG.3622.1_3 - 5.5e-16 58.6 3.4 5.5e-16 58.6 3.4 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.8 MSTRG.3622.1_3 - 3.4e-06 27.4 1.5 3.4e-06 27.4 1.5 1.7 2 0 0 2 2 2 1 HMG-box domain RGS-like PF09128.9 MSTRG.26392.1_2 - 0.38 10.3 2.4 0.28 10.8 0.9 1.4 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain Kelch_1 PF01344.23 MSTRG.29945.1_3 - 2.8e-13 49.1 9.9 2.1e-08 33.5 2.3 3.1 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.4 MSTRG.29945.1_3 - 6.2e-12 45.2 1.2 9e-05 22.5 0.0 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.13 MSTRG.29945.1_3 - 2.5e-11 42.9 1.0 0.00023 20.9 0.1 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.4 MSTRG.29945.1_3 - 9.7e-10 38.1 0.1 5.1e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.4 MSTRG.29945.1_3 - 3.6e-06 27.0 3.0 0.0053 16.9 0.0 2.5 2 1 0 2 2 2 2 Galactose oxidase, central domain DUF1668 PF07893.11 MSTRG.29945.1_3 - 0.0018 17.6 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1668) Kelch_5 PF13854.4 MSTRG.29945.1_3 - 0.012 15.5 0.2 0.034 14.0 0.1 1.9 2 0 0 2 2 2 0 Kelch motif zf-C2H2_4 PF13894.4 MSTRG.91262.1_3 - 5.4e-07 29.8 19.6 0.014 16.1 2.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.24 MSTRG.91262.1_3 - 1.5e-05 25.0 18.9 0.016 15.5 2.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type DUF629 PF04780.10 MSTRG.91262.1_3 - 0.002 16.6 10.4 0.031 12.7 1.7 2.3 1 1 2 3 3 3 2 Protein of unknown function (DUF629) zf-met PF12874.5 MSTRG.91262.1_3 - 0.0044 17.2 11.2 1.4 9.3 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 MSTRG.91262.1_3 - 0.011 15.9 14.2 1.6 9.0 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.3 MSTRG.91262.1_3 - 0.042 14.0 6.3 0.069 13.3 6.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon Acyltransf_C PF16076.3 MSTRG.91262.1_3 - 0.089 12.8 1.9 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Acyltransferase C-terminus FOXP-CC PF16159.3 MSTRG.91262.1_3 - 0.13 12.8 8.3 1.5 9.4 1.7 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.5 MSTRG.91262.1_3 - 0.18 12.0 12.2 2.3 8.5 12.2 2.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.3 MSTRG.91262.1_3 - 0.45 10.5 8.3 3.2 7.7 2.7 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-Di19 PF05605.10 MSTRG.91262.1_3 - 0.5 10.5 12.3 0.41 10.8 1.7 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.4 MSTRG.91262.1_3 - 6.5 7.3 17.3 13 6.3 1.0 4.5 4 1 0 4 4 4 0 Zinc-finger double domain DUF3884 PF13024.4 MSTRG.144398.1_3 - 0.73 9.3 5.2 1.6 8.2 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) Fer4_2 PF12797.5 MSTRG.105315.1_1 - 0.34 11.0 5.1 2 8.6 0.0 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain UPF0242 PF06785.9 MSTRG.66135.1_1 - 0.039 12.6 0.1 0.043 12.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) NDUF_C2 PF06374.9 MSTRG.106169.1_2 - 0.68 9.9 7.2 4.7 7.2 0.7 2.8 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Ribosomal_L24e PF01246.18 MSTRG.106169.1_2 - 5.9 7.1 9.5 7.9 6.6 3.1 2.0 1 1 1 2 2 2 0 Ribosomal protein L24e cobW PF02492.17 MSTRG.37887.1_2 - 0.028 13.9 0.1 0.041 13.3 0.0 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.27 MSTRG.37887.1_2 - 0.038 14.3 0.1 0.063 13.6 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T-box PF00907.20 MSTRG.70474.1_2 - 4.6e-34 118.1 0.5 6.5e-34 117.6 0.5 1.2 1 0 0 1 1 1 1 T-box Kringle PF00051.16 MSTRG.13511.1_1 - 2.2e-17 63.0 6.0 3.4e-17 62.4 6.0 1.3 1 0 0 1 1 1 1 Kringle domain HTH_23 PF13384.4 MSTRG.106298.1_2 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.4 MSTRG.106298.1_2 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.4 MSTRG.106298.1_2 - 0.0099 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain RVT_1 PF00078.25 MSTRG.83900.1_1 - 1.3e-06 28.0 0.0 1.4e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AIG1 PF04548.14 MSTRG.49844.1_2 - 3.8e-05 23.0 3.6 4.1e-05 22.9 3.6 1.1 1 0 0 1 1 1 1 AIG1 family Peptidase_C12 PF01088.19 MSTRG.49844.1_2 - 0.047 13.3 0.2 0.052 13.1 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Noelin-1 PF12308.6 MSTRG.49844.1_2 - 0.32 10.9 5.3 0.38 10.6 5.3 1.2 1 0 0 1 1 1 0 Neurogenesis glycoprotein DDE_3 PF13358.4 MSTRG.211.1_2 - 1.5e-05 24.6 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease BRD4_CDT PF17105.3 MSTRG.13022.1_1 - 0.3 10.6 6.0 0.5 9.9 0.7 2.1 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 CRAL_TRIO_N PF03765.13 MSTRG.125290.1_1 - 1.4e-06 28.3 0.4 2.8e-06 27.3 0.4 1.6 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain Tubulin PF00091.23 MSTRG.93589.1_1 - 1.5e-47 162.2 0.1 1.7e-47 162.0 0.1 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain SF3A2 PF16835.3 MSTRG.137847.1_1 - 2.9e-40 136.4 0.1 4.7e-40 135.7 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.5 MSTRG.137847.1_1 - 2.5e-06 27.5 1.9 2.5e-06 27.5 1.9 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.7 MSTRG.137847.1_1 - 0.00028 20.7 0.2 0.00045 20.0 0.2 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.9 MSTRG.137847.1_1 - 0.066 12.6 3.1 0.12 11.8 3.1 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like zf-C2H2_jaz PF12171.6 MSTRG.137847.1_1 - 3.6 7.9 6.5 7.4 6.9 4.9 2.4 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pkr1 PF08636.8 MSTRG.137603.1_1 - 0.14 12.2 2.5 0.19 11.7 2.5 1.2 1 0 0 1 1 1 0 ER protein Pkr1 XRN_N PF03159.16 MSTRG.75066.1_3 - 3.7e-78 262.1 0.0 4.7e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.4 MSTRG.75066.1_3 - 0.042 13.5 2.2 0.11 12.2 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Nebulin PF00880.16 MSTRG.22192.1_3 - 2.9e-71 234.6 79.9 8.9e-07 28.6 0.6 18.6 19 1 0 19 19 19 16 Nebulin repeat HMA PF00403.24 MSTRG.22192.1_3 - 0.88 9.9 3.3 1.6 9.1 0.2 3.0 4 1 0 4 4 4 0 Heavy-metal-associated domain LRR_8 PF13855.4 MSTRG.46505.1_2 - 1.1e-41 140.2 39.3 2.5e-11 43.0 5.2 7.2 3 3 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.5 MSTRG.46505.1_2 - 2e-27 94.5 38.6 1.2e-05 25.4 0.0 7.8 2 1 10 12 12 12 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 MSTRG.46505.1_2 - 2.4e-07 30.1 31.0 3 8.5 0.9 11.9 11 3 0 11 11 11 3 Leucine Rich Repeat LRR_9 PF14580.4 MSTRG.46505.1_2 - 5.6e-07 29.1 19.0 0.02 14.2 0.7 4.2 1 1 2 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.4 MSTRG.46505.1_2 - 4.2e-05 23.4 1.9 0.54 10.1 0.2 3.7 1 1 2 4 4 4 2 Leucine rich repeats (6 copies) HERV-K_REC PF15695.3 MSTRG.46505.1_2 - 0.016 15.2 0.6 0.73 9.8 0.1 3.3 3 0 0 3 3 3 0 Rec (regulator of expression encoded by corf) of HERV-K-113 LRR_6 PF13516.4 MSTRG.46505.1_2 - 0.057 13.4 42.2 3.5 7.8 0.0 11.1 12 0 0 12 12 12 0 Leucine Rich repeat RsmF_methylt_CI PF17126.3 MSTRG.46505.1_2 - 0.15 12.0 0.3 15 5.6 0.0 4.0 3 2 2 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain CSTF_C PF14304.4 MSTRG.46505.1_2 - 0.34 10.4 5.0 23 4.5 0.1 4.3 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal OTOS PF15182.4 MSTRG.46505.1_3 - 0.13 12.0 0.8 0.28 11.0 0.8 1.5 1 0 0 1 1 1 0 Otospiralin AIG1 PF04548.14 MSTRG.37959.1_2 - 1.8e-61 207.0 0.0 2.5e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.21 MSTRG.37959.1_2 - 1.8e-09 37.5 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.16 MSTRG.37959.1_2 - 0.0089 15.4 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.21 MSTRG.37959.1_2 - 0.038 13.9 7.7 1.2 9.1 0.7 2.6 3 0 0 3 3 3 0 Dynamin family DUF258 PF03193.14 MSTRG.37959.1_2 - 0.061 13.1 0.9 0.11 12.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF3750 PF12570.6 MSTRG.37959.1_2 - 0.24 11.9 9.9 7.3 7.2 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3750) Med2 PF11214.6 MSTRG.37959.1_2 - 0.32 11.1 3.6 0.65 10.1 3.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 MbtH PF03621.11 MSTRG.37959.1_2 - 0.45 9.9 7.2 73 2.8 0.1 4.2 1 1 3 4 4 4 0 MbtH-like protein DUF4746 PF15928.3 MSTRG.37959.1_2 - 5.8 6.1 8.1 9.7 5.4 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AMA-1 PF02430.13 MSTRG.37959.1_3 - 0.21 10.3 0.4 0.3 9.9 0.4 1.0 1 0 0 1 1 1 0 Apical membrane antigen 1 SseC PF04888.10 MSTRG.37959.1_3 - 0.29 10.5 1.3 0.39 10.0 1.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ETRAMP PF09716.8 MSTRG.37959.1_3 - 0.33 10.9 0.9 0.42 10.6 0.2 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TT_ORF1 PF02956.12 MSTRG.37959.1_3 - 7.5 5.0 18.8 12 4.2 18.8 1.3 1 0 0 1 1 1 0 TT viral orf 1 TMEM239 PF15841.3 MSTRG.26350.1_2 - 1.7 8.3 6.2 2.5 7.8 6.2 1.4 1 1 0 1 1 1 0 Transmembrane protein 239 family Collagen PF01391.16 MSTRG.26350.1_3 - 0.0007 19.2 0.4 0.0011 18.6 0.4 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Paramecium_SA PF01508.14 MSTRG.26350.1_3 - 0.04 14.2 7.7 0.088 13.1 7.7 1.5 1 1 0 1 1 1 0 Paramecium surface antigen domain Metallothi_Euk2 PF12809.5 MSTRG.26350.1_3 - 0.55 10.4 14.4 69 3.7 14.4 2.2 1 1 0 1 1 1 0 Eukaryotic metallothionein Antifungal_pept PF11410.6 MSTRG.33332.1_2 - 7.5 6.4 10.5 16 5.4 1.5 3.7 1 1 2 3 3 3 0 Antifungal peptide ABC_tran PF00005.25 MSTRG.129885.1_2 - 2.2e-11 44.3 0.0 4.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.17 MSTRG.129885.1_2 - 1.9e-05 24.1 0.1 2.4e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.4 MSTRG.129885.1_2 - 0.0013 18.8 0.3 0.083 13.0 0.3 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Acyl-CoA_dh_1 PF00441.22 MSTRG.129885.1_2 - 0.071 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1031 PF06275.9 MSTRG.48424.1_3 - 0.035 14.2 0.2 0.059 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) PRY PF13765.4 MSTRG.98011.1_1 - 5.3e-06 25.8 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.26 MSTRG.98011.1_1 - 0.00085 19.3 0.4 0.0015 18.6 0.4 1.4 1 0 0 1 1 1 1 SPRY domain Anti-adapt_IraP PF10796.7 MSTRG.33971.1_1 - 0.069 13.6 1.0 0.079 13.4 0.1 1.6 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Cpn60_TCP1 PF00118.22 MSTRG.19165.1_1 - 2.7e-63 214.2 0.3 3.2e-63 213.9 0.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family K-box PF01486.15 MSTRG.51075.1_2 - 0.024 14.7 1.0 0.033 14.3 1.0 1.2 1 0 0 1 1 1 0 K-box region Serine_rich PF08824.8 MSTRG.51075.1_2 - 0.055 13.3 0.1 0.067 13.1 0.1 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain Plexin_cytopl PF08337.10 MSTRG.51075.1_2 - 0.071 11.6 0.7 0.11 11.0 0.0 1.6 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain RVT_1 PF00078.25 MSTRG.82693.1_3 - 1.5e-14 53.9 0.1 1.7e-14 53.7 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAP1_N PF04849.11 MSTRG.118475.1_1 - 0.0064 15.6 1.9 0.0071 15.5 1.9 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region bZIP_1 PF00170.19 MSTRG.118475.1_1 - 0.0077 16.2 1.6 0.0094 15.9 1.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor Miff PF05644.9 MSTRG.118475.1_1 - 0.011 15.3 0.5 0.014 15.0 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Tropomyosin_1 PF12718.5 MSTRG.118475.1_1 - 0.017 15.1 3.1 0.02 14.9 3.1 1.0 1 0 0 1 1 1 0 Tropomyosin like HALZ PF02183.16 MSTRG.118475.1_1 - 0.035 14.2 4.7 0.035 14.2 4.7 1.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper Nop25 PF09805.7 MSTRG.118475.1_1 - 0.045 14.1 0.3 0.048 14.0 0.3 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) APG6 PF04111.10 MSTRG.118475.1_1 - 0.057 12.7 0.8 0.06 12.6 0.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.11 MSTRG.118475.1_1 - 0.082 13.4 0.9 0.099 13.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.12 MSTRG.118475.1_1 - 0.087 12.5 2.6 0.097 12.3 2.6 1.0 1 0 0 1 1 1 0 IncA protein 4HBT PF03061.20 MSTRG.118475.1_1 - 0.094 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase superfamily CagZ PF09053.8 MSTRG.49000.1_3 - 0.12 11.9 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 CagZ AIG1 PF04548.14 MSTRG.39806.1_1 - 4e-59 199.4 2.1 4.9e-59 199.1 2.1 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.21 MSTRG.39806.1_1 - 2.5e-09 37.1 0.3 6.9e-09 35.7 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.14 MSTRG.39806.1_1 - 7.9e-05 22.5 0.7 7.9e-05 22.5 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Guanylate_kin PF00625.19 MSTRG.39806.1_1 - 0.01 15.4 0.1 0.01 15.4 0.1 2.4 2 0 0 2 2 2 0 Guanylate kinase ABC_tran PF00005.25 MSTRG.39806.1_1 - 0.081 13.3 2.5 0.4 11.1 2.5 2.2 1 1 0 1 1 1 0 ABC transporter RHSP PF07999.9 MSTRG.39806.1_1 - 0.086 11.5 0.9 0.65 8.6 0.1 2.4 2 1 1 3 3 3 0 Retrotransposon hot spot protein RNA_helicase PF00910.20 MSTRG.39806.1_1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 RNA helicase RNA_binding PF01877.15 MSTRG.39806.1_1 - 0.15 12.2 5.5 1.7 8.8 5.5 2.4 1 1 0 1 1 1 0 RNA binding Tho2 PF11262.6 MSTRG.39806.1_1 - 3.1 6.8 6.5 4.2 6.3 6.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.17 MSTRG.39806.1_1 - 9.5 3.8 9.3 1.2 6.8 0.2 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family MFS_MOT1 PF16983.3 MSTRG.1629.1_2 - 0.82 9.7 2.4 21 5.2 2.4 2.6 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily zf-TRM13_CCCH PF11722.6 MSTRG.1629.1_3 - 0.0048 16.5 0.9 3.8e+02 0.8 0.0 6.1 7 0 0 7 7 7 0 CCCH zinc finger in TRM13 protein SAM_1 PF00536.28 MSTRG.56880.1_2 - 2.3e-14 53.4 0.0 3.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 MSTRG.56880.1_2 - 7e-06 25.9 0.0 9.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.14 MSTRG.56880.1_2 - 0.036 13.9 0.0 0.07 13.0 0.0 1.5 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Maf_N PF08383.9 MSTRG.56880.1_2 - 0.11 12.2 0.1 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Maf N-terminal region Ribul_P_3_epim PF00834.17 MSTRG.105975.1_2 - 1.1e-20 73.8 0.1 1.4e-20 73.5 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.12 MSTRG.105975.1_2 - 0.022 14.0 0.1 0.028 13.6 0.1 1.1 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.17 MSTRG.105975.1_2 - 0.05 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Syntaxin-6_N PF09177.9 MSTRG.85135.1_2 - 0.055 13.9 0.9 0.1 13.0 0.9 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DASH_Hsk3 PF08227.9 MSTRG.85135.1_2 - 0.5 10.6 2.8 0.98 9.7 2.8 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF1664 PF07889.10 MSTRG.85135.1_2 - 1.5 8.7 5.1 2.2 8.1 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LRR_9 PF14580.4 MSTRG.19945.2_3 - 7.7e-18 64.5 0.6 1.6e-17 63.4 0.5 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.5 MSTRG.19945.2_3 - 3.7e-12 46.1 15.0 4.1e-09 36.4 3.7 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 MSTRG.19945.2_3 - 1.1e-07 31.4 7.4 7.5e-07 28.7 4.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.4 MSTRG.19945.2_3 - 0.00023 20.8 6.5 0.12 12.4 0.5 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.31 MSTRG.19945.2_3 - 0.13 12.7 9.9 1.3 9.6 0.3 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat SDA1 PF05285.10 MSTRG.19945.2_3 - 0.71 9.1 33.5 1.3 8.2 33.5 1.3 1 0 0 1 1 1 0 SDA1 SecB PF02556.12 MSTRG.45428.1_3 - 0.095 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit SecB Fungus-induced PF10917.6 MSTRG.109408.1_3 - 0.042 14.0 1.0 0.056 13.6 1.0 1.2 1 0 0 1 1 1 0 Fungus-induced protein Peptidase_C1 PF00112.21 MSTRG.9011.1_3 - 3.2e-78 262.7 4.3 4.1e-78 262.3 4.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 MSTRG.9011.1_3 - 8.5e-18 64.4 4.9 1.4e-17 63.7 4.9 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 MSTRG.9011.1_3 - 2.9e-05 22.9 2.3 0.0011 17.7 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family TruB_C_2 PF16198.3 MSTRG.41193.1_2 - 0.098 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Ribosomal_S17e PF00833.16 MSTRG.142196.1_3 - 3.6e-32 110.8 0.1 4e-32 110.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cyclin_N PF00134.21 MSTRG.1484.1_1 - 3.3e-30 104.4 0.7 5.1e-30 103.7 0.7 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RVT_1 PF00078.25 MSTRG.13804.1_3 - 2.2e-06 27.2 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.23 MSTRG.104387.1_3 - 1.5e-09 37.5 0.0 2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.104387.1_3 - 1.3e-06 27.8 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KfrA_N PF11740.6 MSTRG.104387.1_3 - 0.036 14.6 0.0 0.067 13.7 0.0 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term ABC1 PF03109.14 MSTRG.104387.1_3 - 0.046 13.7 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC1 family LIX1 PF14954.4 MSTRG.19757.1_2 - 3.7e-136 452.1 0.3 4.9e-136 451.7 0.3 1.1 1 0 0 1 1 1 1 Limb expression 1 Methyltrn_RNA_4 PF09936.7 MSTRG.134620.1_3 - 0.46 10.2 3.7 0.46 10.2 3.7 1.0 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase YL1 PF05764.11 MSTRG.134620.1_3 - 3.8 7.5 14.3 4.1 7.3 14.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Myb_Cef PF11831.6 MSTRG.134620.1_3 - 5.1 6.5 12.2 5.5 6.4 12.2 1.0 1 0 0 1 1 1 0 pre-mRNA splicing factor component Syndecan PF01034.18 MSTRG.129165.1_3 - 0.085 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Syndecan domain DnaJ PF00226.29 MSTRG.55237.1_2 - 5.9e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.11 MSTRG.55237.1_2 - 0.0049 16.7 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 Auts2 PF15336.4 MSTRG.27392.1_1 - 7.8e-05 22.8 4.5 7.8e-05 22.8 4.5 1.8 2 0 0 2 2 2 1 Autism susceptibility gene 2 protein LELP1 PF15042.4 MSTRG.6536.1_1 - 0.0018 18.6 0.2 0.0022 18.3 0.2 1.1 1 0 0 1 1 1 1 Late cornified envelope-like proline-rich protein 1 Thioredoxin_6 PF13848.4 MSTRG.97699.1_3 - 2.4e-22 79.7 0.0 9.5e-20 71.2 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.18 MSTRG.97699.1_3 - 2.4e-22 78.7 0.0 2.4e-21 75.5 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.4 MSTRG.97699.1_3 - 3.6e-05 24.0 0.2 0.00041 20.6 0.1 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain ANTH PF07651.14 MSTRG.117844.1_1 - 1.1e-56 191.8 0.6 1.3e-56 191.5 0.6 1.0 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.18 MSTRG.117844.1_1 - 4.6e-12 46.0 0.1 7.6e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain BLM10_mid PF16507.3 MSTRG.8684.1_1 - 2.5e-75 254.0 0.6 9.1e-74 248.9 0.1 2.3 2 1 0 2 2 2 1 Proteasome-substrate-size regulator, mid region Fructosamin_kin PF03881.12 MSTRG.39060.1_1 - 8e-12 44.8 0.0 8.3e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.21 MSTRG.39060.1_1 - 0.00049 20.0 0.0 0.00051 19.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Bromodomain PF00439.23 MSTRG.126515.1_2 - 2.9e-19 68.8 0.0 3.3e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Bromodomain UPF1_Zn_bind PF09416.8 MSTRG.88425.1_1 - 3.9e-45 153.4 1.2 4.3e-45 153.3 1.2 1.0 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) Lamprin PF06403.9 MSTRG.6264.1_2 - 0.021 14.7 0.2 0.028 14.2 0.2 1.1 1 0 0 1 1 1 0 Lamprin DUF4713 PF15831.3 MSTRG.8260.1_1 - 3.6 8.0 22.9 2.1 8.7 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) RhoGAP PF00620.25 MSTRG.29013.1_1 - 9.1e-11 41.7 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain W2 PF02020.16 MSTRG.10104.1_2 - 8.2e-15 54.6 0.5 1.3e-14 54.0 0.5 1.2 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Oxysterol_BP PF01237.16 MSTRG.15097.1_2 - 9.2e-64 215.4 0.1 1e-63 215.3 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Peptidase_M24 PF00557.22 MSTRG.90045.1_1 - 1.1e-55 188.5 0.1 8.7e-54 182.2 0.1 2.5 3 0 0 3 3 3 2 Metallopeptidase family M24 AMP_N PF05195.14 MSTRG.90045.1_1 - 1.1e-28 99.3 0.0 2.1e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GYF PF02213.14 MSTRG.134622.1_3 - 5.5e-21 73.9 0.1 7.6e-21 73.5 0.1 1.2 1 0 0 1 1 1 1 GYF domain DUF4339 PF14237.4 MSTRG.134622.1_3 - 0.00022 20.8 0.1 0.00036 20.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) IFR3_antag PF14754.4 MSTRG.48091.1_1 - 0.083 11.9 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase Ras PF00071.20 MSTRG.18116.1_3 - 6e-15 55.1 0.4 9e-15 54.5 0.1 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.11 MSTRG.18116.1_3 - 1e-14 54.7 0.3 2e-14 53.7 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.4 MSTRG.18116.1_3 - 0.0012 19.0 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.10 MSTRG.18116.1_3 - 0.0052 16.0 0.2 0.0076 15.5 0.0 1.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region TsaE PF02367.15 MSTRG.18116.1_3 - 0.0075 16.1 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.24 MSTRG.18116.1_3 - 0.0097 15.5 0.0 0.012 15.2 0.0 1.3 1 1 0 1 1 1 1 Sigma-54 interaction domain MMR_HSR1 PF01926.21 MSTRG.18116.1_3 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.7 MSTRG.18116.1_3 - 0.021 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.11 MSTRG.18116.1_3 - 0.024 13.7 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.4 MSTRG.18116.1_3 - 0.027 14.7 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.19 MSTRG.18116.1_3 - 0.028 13.8 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family TniB PF05621.9 MSTRG.18116.1_3 - 0.029 13.4 0.0 0.11 11.6 0.0 1.7 1 1 1 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.4 MSTRG.18116.1_3 - 0.059 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.12 MSTRG.18116.1_3 - 0.071 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.27 MSTRG.18116.1_3 - 0.072 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.4 MSTRG.18116.1_3 - 0.091 12.4 0.1 0.96 9.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain NOA36 PF06524.10 MSTRG.35656.2_2 - 1.5 8.0 8.4 1.6 7.9 8.4 1.0 1 0 0 1 1 1 0 NOA36 protein La PF05383.15 MSTRG.75809.1_3 - 1.6e-21 76.0 0.1 2.4e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.20 MSTRG.75809.1_3 - 7.2e-10 38.4 0.0 1.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPATA24 PF15175.4 MSTRG.75809.1_3 - 0.031 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Myosin_head PF00063.19 MSTRG.88084.2_2 - 5.2e-24 84.3 0.1 5.5e-24 84.2 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_hydro_20 PF00728.20 MSTRG.73901.1_2 - 0.037 13.3 0.0 0.042 13.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain DDE_3 PF13358.4 MSTRG.80525.1_2 - 6.1e-08 32.4 0.4 8.3e-08 32.0 0.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2 PF00096.24 MSTRG.113793.1_3 - 1.1e-10 41.3 9.6 2.7e-05 24.2 0.9 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.113793.1_3 - 8.4e-08 32.2 1.1 8.4e-08 32.2 1.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.113793.1_3 - 2.4e-06 27.7 8.6 0.013 16.1 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.113793.1_3 - 1.3e-05 25.2 6.9 0.0095 16.1 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding NOA36 PF06524.10 MSTRG.113793.1_3 - 0.015 14.5 3.7 0.019 14.2 3.7 1.1 1 0 0 1 1 1 0 NOA36 protein zf-H2C2_5 PF13909.4 MSTRG.113793.1_3 - 0.064 12.9 9.1 0.45 10.2 2.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.5 MSTRG.113793.1_3 - 0.083 13.2 9.1 0.25 11.6 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.13 MSTRG.113793.1_3 - 0.11 12.2 0.8 0.24 11.2 0.8 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_7 PF15269.4 MSTRG.113793.1_3 - 0.13 12.3 6.5 0.52 10.3 1.2 2.2 1 1 1 2 2 2 0 Zinc-finger zf-C2HE PF16278.3 MSTRG.113793.1_3 - 0.14 12.5 0.6 0.14 12.5 0.6 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.5 MSTRG.113793.1_3 - 0.17 12.1 5.0 6.4 7.0 0.8 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) MIP PF00230.18 MSTRG.103595.1_2 - 6.8e-25 88.0 3.6 8.2e-25 87.7 3.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Toxin_24 PF08094.9 MSTRG.62035.1_1 - 0.089 12.5 1.9 0.67 9.7 0.3 2.4 1 1 1 2 2 2 0 Conotoxin TVIIA/GS family DUF2065 PF09838.7 MSTRG.62035.1_3 - 0.064 13.2 2.0 1.6 8.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) zf-NF-X1 PF01422.15 MSTRG.64129.1_2 - 0.16 11.9 4.1 3.2 7.8 0.3 2.5 2 0 0 2 2 2 0 NF-X1 type zinc finger DUF4118 PF13493.4 MSTRG.6667.1_1 - 2 8.1 6.1 0.55 9.9 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) DNA_pol3_delta PF06144.11 MSTRG.1587.1_2 - 0.16 11.6 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Baculo_11_kDa PF06143.9 MSTRG.31466.1_1 - 0.019 14.4 2.4 0.027 13.9 2.4 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family V-set PF07686.15 MSTRG.128892.1_2 - 0.075 13.1 0.0 0.09 12.8 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin V-set domain Pro_isomerase PF00160.19 MSTRG.33388.1_2 - 1.2e-45 155.5 0.1 1.4e-45 155.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.15 MSTRG.125912.1_1 - 0.018 15.0 0.0 0.054 13.5 0.0 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Pentaxin PF00354.15 MSTRG.38469.1_3 - 4.4e-20 72.0 0.1 5.7e-20 71.7 0.1 1.0 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.4 MSTRG.38469.1_3 - 0.0089 16.0 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily betaPIX_CC PF16523.3 MSTRG.107533.2_1 - 0.053 13.2 0.6 0.081 12.6 0.6 1.2 1 0 0 1 1 1 0 betaPIX coiled coil DUF1340 PF07067.9 MSTRG.115485.1_2 - 0.00066 19.0 2.3 0.00089 18.6 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1340) Phage_int_SAM_5 PF13102.4 MSTRG.115485.1_2 - 0.12 12.6 9.0 0.16 12.2 9.0 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain RVT_1 PF00078.25 MSTRG.36738.1_3 - 2.4e-14 53.3 0.0 2.6e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CDGSH PF09360.8 MSTRG.116420.1_1 - 0.0081 16.2 0.6 0.015 15.4 0.6 1.5 1 1 0 1 1 1 1 Iron-binding zinc finger CDGSH type zf-CSL PF05207.11 MSTRG.116420.1_1 - 0.06 12.9 0.1 0.092 12.4 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger SDA1 PF05285.10 MSTRG.73941.2_3 - 0.52 9.6 11.1 0.53 9.5 11.1 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.8 MSTRG.73941.2_3 - 2.1 7.5 10.3 2.1 7.5 10.3 1.1 1 0 0 1 1 1 0 BUD22 DUF4503 PF14951.4 MSTRG.67129.1_2 - 3.3e-12 45.4 0.0 4.5e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) STAT_bind PF02864.13 MSTRG.55415.1_1 - 2.5e-83 279.7 0.0 2.5e-83 279.7 0.0 1.9 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_int PF02865.15 MSTRG.55415.1_1 - 1.7e-30 105.8 3.6 1.7e-30 105.8 3.6 2.9 2 1 1 3 3 3 1 STAT protein, protein interaction domain STAT_alpha PF01017.18 MSTRG.55415.1_1 - 6.2e-11 42.3 16.8 2.4e-10 40.4 16.8 1.9 1 1 0 1 1 1 1 STAT protein, all-alpha domain SH2 PF00017.22 MSTRG.55415.1_1 - 3.6e-07 30.0 0.0 1.1e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Mnd1 PF03962.13 MSTRG.55415.1_1 - 0.048 13.4 3.7 0.097 12.4 3.7 1.4 1 0 0 1 1 1 0 Mnd1 family OmpH PF03938.12 MSTRG.55415.1_1 - 0.24 11.3 5.3 0.45 10.4 5.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HIP1_clath_bdg PF16515.3 MSTRG.55415.1_1 - 0.37 11.3 8.2 0.26 11.8 4.0 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Laminin_II PF06009.10 MSTRG.55415.1_1 - 0.75 9.7 3.5 1.9 8.4 3.5 1.6 1 0 0 1 1 1 0 Laminin Domain II DivIVA PF05103.11 MSTRG.55415.1_1 - 2.9 7.8 6.0 14 5.7 5.2 2.3 2 0 0 2 2 2 0 DivIVA protein DUF745 PF05335.11 MSTRG.55415.1_1 - 4.9 6.7 7.3 9 5.9 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) GCM PF03615.13 MSTRG.65486.1_1 - 1.7e-71 238.5 2.7 2.4e-71 238.0 2.7 1.2 1 0 0 1 1 1 1 GCM motif protein FAM76 PF16046.3 MSTRG.81079.3_1 - 2e-35 122.5 24.3 2.4e-35 122.2 24.3 1.1 1 0 0 1 1 1 1 FAM76 protein Phage_GP20 PF06810.9 MSTRG.81079.3_1 - 0.018 14.7 5.1 0.033 13.9 5.1 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 MPS2 PF17060.3 MSTRG.81079.3_1 - 0.13 11.3 11.3 0.19 10.9 11.3 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF4755 PF15947.3 MSTRG.81079.3_1 - 0.43 10.4 3.4 0.12 12.2 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4755) DUF4887 PF16228.3 MSTRG.81079.3_1 - 2.8 7.7 23.9 1.2 8.8 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) OmpH PF03938.12 MSTRG.81079.3_1 - 9.8 6.0 14.5 19 5.1 14.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DDE_3 PF13358.4 MSTRG.129696.1_1 - 0.022 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.16 MSTRG.129696.1_3 - 3.5e-13 49.5 4.3 9.1e-13 48.1 4.3 1.8 1 1 0 1 1 1 1 Transposase HTH_32 PF13565.4 MSTRG.129696.1_3 - 0.015 15.8 0.7 0.026 15.0 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain RhoGAP PF00620.25 MSTRG.32441.1_1 - 6.6e-29 100.6 0.1 7.1e-29 100.4 0.1 1.0 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.9 MSTRG.32441.1_1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Recep_L_domain PF01030.22 MSTRG.104829.1_2 - 1.9e-28 98.7 0.2 3e-28 98.1 0.2 1.3 1 0 0 1 1 1 1 Receptor L domain NAD_binding_8 PF13450.4 MSTRG.23722.1_2 - 7.9e-13 48.3 0.7 9.6e-13 48.1 0.7 1.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.22 MSTRG.23722.1_2 - 4.6e-07 29.1 1.2 5.1e-07 29.0 1.2 1.0 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.22 MSTRG.23722.1_2 - 3.3e-06 26.5 0.1 3.8e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.22 MSTRG.23722.1_2 - 9.1e-06 25.4 1.9 1e-05 25.2 1.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 MSTRG.23722.1_2 - 0.00024 20.3 0.1 0.00025 20.3 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 MSTRG.23722.1_2 - 0.00027 20.2 2.2 0.00032 20.0 2.2 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.5 MSTRG.23722.1_2 - 0.00052 19.3 1.5 0.00061 19.1 1.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.15 MSTRG.23722.1_2 - 0.0011 18.1 0.2 0.0011 18.1 0.2 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.25 MSTRG.23722.1_2 - 0.0024 18.3 0.7 0.0031 17.9 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.9 MSTRG.23722.1_2 - 0.0025 16.6 0.0 0.0026 16.5 0.0 1.0 1 0 0 1 1 1 1 MCRA family HI0933_like PF03486.12 MSTRG.23722.1_2 - 0.0033 16.1 1.1 0.004 15.8 1.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.4 MSTRG.23722.1_2 - 0.005 16.0 0.3 0.0055 15.9 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.16 MSTRG.23722.1_2 - 0.017 13.5 0.1 0.02 13.3 0.1 1.0 1 0 0 1 1 1 0 GDP dissociation inhibitor GIDA PF01134.20 MSTRG.23722.1_2 - 0.03 13.3 1.0 0.034 13.1 1.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.19 MSTRG.23722.1_2 - 0.037 13.2 1.6 0.051 12.7 1.6 1.3 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.16 MSTRG.23722.1_2 - 0.063 13.0 0.3 0.072 12.8 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1188 PF06690.9 MSTRG.23722.1_2 - 0.097 12.1 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) K_oxygenase PF13434.4 MSTRG.23722.1_2 - 0.17 10.8 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) RIIa PF02197.15 MSTRG.68701.1_2 - 3e-15 55.5 0.0 4.6e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit PCI PF01399.25 MSTRG.42890.1_2 - 6.7e-10 39.3 0.6 9.8e-10 38.8 0.6 1.2 1 0 0 1 1 1 1 PCI domain RepA1_leader PF08048.10 MSTRG.109077.1_2 - 5.8 7.1 14.1 0.28 11.4 1.2 2.6 1 1 1 2 2 2 0 Tap RepA1 leader peptide PH PF00169.27 MSTRG.105267.1_1 - 4.1e-05 23.9 0.0 5.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 PH domain PmoA PF14100.4 MSTRG.119874.1_2 - 0.069 12.5 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 Methane oxygenase PmoA DDE_3 PF13358.4 MSTRG.119874.1_3 - 6.4e-05 22.6 0.1 8.5e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease mRNA_cap_C PF03919.13 MSTRG.119874.1_3 - 0.038 14.5 0.0 0.051 14.1 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain BMF PF15185.4 MSTRG.119874.1_3 - 0.18 11.4 0.1 0.22 11.1 0.1 1.1 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis LST1 PF05083.11 MSTRG.46060.1_1 - 0.079 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 LST-1 protein Fz PF01392.20 MSTRG.6386.1_3 - 2.1e-49 166.8 18.8 4.9e-28 97.9 4.7 2.1 2 0 0 2 2 2 2 Fz domain PAS_3 PF08447.10 MSTRG.64134.1_1 - 0.013 15.7 0.8 0.016 15.4 0.8 1.2 1 0 0 1 1 1 0 PAS fold ERM PF00769.17 MSTRG.64134.1_1 - 0.064 12.9 9.7 0.087 12.5 9.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CmcI PF04989.10 MSTRG.64134.1_1 - 0.081 12.5 0.0 0.093 12.3 0.0 1.0 1 0 0 1 1 1 0 Cephalosporin hydroxylase UFD1 PF03152.12 MSTRG.64134.1_1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 RBD-FIP PF09457.8 MSTRG.64134.1_1 - 0.28 11.0 1.9 0.5 10.2 1.9 1.6 1 1 0 1 1 1 0 FIP domain Tox-GHH PF15636.4 MSTRG.64134.1_1 - 0.38 10.6 9.8 0.62 9.9 9.8 1.4 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin NINJA_B PF16136.3 MSTRG.64134.1_1 - 1.2 9.4 9.0 1.4 9.1 9.0 1.1 1 0 0 1 1 1 0 Putative nuclear localisation signal MORN PF02493.18 MSTRG.64134.1_3 - 0.048 13.4 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 MORN repeat Med13_C PF06333.10 MSTRG.56130.1_3 - 1.3e-12 47.2 0.1 1.4e-12 47.1 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal BEN PF10523.7 MSTRG.81947.1_3 - 2.1e-05 24.5 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 BEN domain Collagen PF01391.16 MSTRG.12715.1_1 - 1.8e-17 62.7 55.2 1.6e-10 40.5 28.1 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) WD40 PF00400.30 MSTRG.10381.1_3 - 0.0028 18.3 0.1 0.23 12.3 0.0 2.4 3 0 0 3 3 3 2 WD domain, G-beta repeat MutS_IV PF05190.16 MSTRG.118241.1_2 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 MutS family domain IV DUF4821 PF16092.3 MSTRG.11217.1_2 - 0.095 12.2 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Ig_3 PF13927.4 MSTRG.98308.2_2 - 1.8e-08 34.7 0.2 2.5e-08 34.3 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 MSTRG.98308.2_2 - 2e-08 34.0 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.4 MSTRG.98308.2_2 - 4.8e-07 29.9 0.1 7.4e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.98308.2_2 - 0.01 15.8 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.15 MSTRG.98308.2_2 - 0.037 14.1 0.1 0.05 13.6 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain C1-set PF07654.13 MSTRG.98308.2_2 - 0.049 14.0 0.2 0.071 13.5 0.2 1.3 1 0 0 1 1 1 0 Immunoglobulin C1-set domain C2-set_2 PF08205.10 MSTRG.98308.2_2 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain zf-MYND PF01753.16 MSTRG.113690.1_2 - 0.052 13.5 0.2 0.075 13.0 0.2 1.2 1 0 0 1 1 1 0 MYND finger Trypsin PF00089.24 MSTRG.30185.1_3 - 1.2e-30 106.8 1.4 1.7e-30 106.4 1.4 1.1 1 0 0 1 1 1 1 Trypsin zinc_ribbon_5 PF13719.4 MSTRG.137074.1_2 - 2 8.1 12.7 62 3.3 0.1 5.7 6 0 0 6 6 6 0 zinc-ribbon domain Fez1 PF06818.13 MSTRG.40945.1_1 - 0.00025 21.4 10.9 0.00025 21.4 10.9 2.1 1 1 1 2 2 2 1 Fez1 IncA PF04156.12 MSTRG.40945.1_1 - 0.0031 17.2 20.6 1.9 8.1 20.6 2.1 1 1 0 1 1 1 1 IncA protein ATG16 PF08614.9 MSTRG.40945.1_1 - 0.013 15.6 20.6 0.094 12.8 20.6 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FAM76 PF16046.3 MSTRG.40945.1_1 - 0.013 14.7 14.9 0.019 14.2 14.9 1.1 1 0 0 1 1 1 0 FAM76 protein Tup_N PF08581.8 MSTRG.40945.1_1 - 0.34 11.1 11.9 0.68 10.2 11.9 1.5 1 0 0 1 1 1 0 Tup N-terminal DUF3713 PF12506.6 MSTRG.40945.1_1 - 0.53 10.5 2.4 1.1 9.4 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) CALCOCO1 PF07888.9 MSTRG.40945.1_1 - 1.5 7.2 21.3 2 6.8 21.3 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HemX PF04375.12 MSTRG.40945.1_1 - 1.9 7.6 13.2 2.9 6.9 8.4 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc7 PF08317.9 MSTRG.40945.1_1 - 2 7.1 21.0 3.3 6.4 21.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein NIT PF08376.8 MSTRG.40945.1_1 - 5 7.4 6.0 8.1 6.7 5.3 1.7 1 1 0 1 1 1 0 Nitrate and nitrite sensing RVT_1 PF00078.25 MSTRG.99175.1_1 - 2.2e-12 46.8 0.0 2.5e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) XPG_N PF00752.15 MSTRG.55097.1_2 - 3.6e-35 120.3 0.0 8e-35 119.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.16 MSTRG.55097.1_2 - 2.2e-27 95.1 0.2 5.1e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.18 MSTRG.55097.1_2 - 1.7e-07 31.6 0.0 7.8e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.4 MSTRG.55097.1_2 - 0.0073 16.8 0.0 0.032 14.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain EGF_CA PF07645.13 MSTRG.90335.1_1 - 3.2e-20 71.9 63.3 2.5e-09 37.0 8.0 5.4 5 1 0 5 5 5 4 Calcium-binding EGF domain TB PF00683.15 MSTRG.90335.1_1 - 2.5e-14 52.5 5.9 2.5e-14 52.5 5.9 3.0 3 1 0 3 3 3 1 TB domain cEGF PF12662.5 MSTRG.90335.1_1 - 4.1e-06 26.5 7.7 0.00024 20.8 0.9 5.3 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF_3 PF12947.5 MSTRG.90335.1_1 - 3.1e-05 23.9 46.1 0.00019 21.4 7.1 5.5 5 0 0 5 5 5 3 EGF domain FXa_inhibition PF14670.4 MSTRG.90335.1_1 - 0.00036 20.6 18.8 0.0046 17.1 8.9 5.2 5 0 0 5 5 5 2 Coagulation Factor Xa inhibitory site hEGF PF12661.5 MSTRG.90335.1_1 - 0.00075 20.0 39.1 0.0019 18.7 5.0 6.3 5 1 0 5 5 5 3 Human growth factor-like EGF EGF_2 PF07974.11 MSTRG.90335.1_1 - 0.017 15.4 7.0 0.017 15.4 7.0 4.9 3 1 1 4 4 4 0 EGF-like domain EGF PF00008.25 MSTRG.90335.1_2 - 4.4e-06 26.7 16.2 1.7e-05 24.9 6.7 3.0 2 0 0 2 2 2 2 EGF-like domain Plasmod_Pvs28 PF06247.9 MSTRG.90335.1_2 - 0.0023 18.1 1.6 0.0023 18.1 1.6 2.0 2 0 0 2 2 2 1 Pvs28 EGF domain FXa_inhibition PF14670.4 MSTRG.90335.1_2 - 0.023 14.9 6.9 0.023 14.9 6.9 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site hEGF PF12661.5 MSTRG.90335.1_2 - 6.7 7.4 16.0 0.9 10.2 6.4 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF I_LWEQ PF01608.15 MSTRG.1832.1_3 - 1e-49 168.6 7.0 1e-49 168.6 7.0 4.4 2 1 1 4 4 4 1 I/LWEQ domain HIP1_clath_bdg PF16515.3 MSTRG.1832.1_3 - 2.4e-32 111.4 20.5 2.4e-32 111.4 20.5 5.7 4 2 2 6 6 6 3 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3584 PF12128.6 MSTRG.1832.1_3 - 2.7e-05 21.8 41.8 6.4e-05 20.6 41.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CENP-H PF05837.10 MSTRG.1832.1_3 - 0.0084 16.4 12.3 0.0084 16.4 12.3 4.9 4 1 1 5 5 5 1 Centromere protein H (CENP-H) P53_TAD PF08563.9 MSTRG.125861.1_3 - 0.25 10.6 0.2 0.34 10.2 0.2 1.2 1 0 0 1 1 1 0 P53 transactivation motif DUF3915 PF13054.4 MSTRG.125861.1_3 - 2.2 8.1 7.9 0.72 9.7 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) MDH PF02315.14 MSTRG.109811.1_1 - 0.83 9.6 2.7 9.4 6.2 0.2 2.1 1 1 1 2 2 2 0 Methanol dehydrogenase beta subunit DUF3039 PF11238.6 MSTRG.112929.1_1 - 2.7 7.7 5.8 0.4 10.4 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zf-C4 PF00105.16 MSTRG.112929.1_2 - 6.6e-33 112.9 13.2 1.4e-32 111.8 13.2 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DNA_ligase_ZBD PF03119.14 MSTRG.51299.1_1 - 0.036 14.0 0.2 2 8.4 0.3 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain CTD PF12815.5 MSTRG.68888.1_2 - 0.11 12.9 0.0 0.5 10.8 0.0 2.1 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 LIM PF00412.20 MSTRG.88972.1_2 - 7.5e-09 35.6 3.8 1e-08 35.1 3.8 1.2 1 0 0 1 1 1 1 LIM domain EMI PF07546.11 MSTRG.2845.1_1 - 6.8e-05 23.4 0.2 0.00013 22.5 0.2 1.5 1 0 0 1 1 1 1 EMI domain FH2 PF02181.21 MSTRG.2845.1_1 - 0.00088 18.4 5.5 0.0074 15.3 0.1 3.3 1 1 2 4 4 4 1 Formin Homology 2 Domain CENP-F_leu_zip PF10473.7 MSTRG.2845.1_1 - 0.0017 18.3 2.4 0.0017 18.3 2.4 4.6 4 1 1 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.11 MSTRG.2845.1_1 - 0.012 14.1 3.4 0.029 12.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF2195 PF09961.7 MSTRG.2845.1_1 - 0.04 13.7 0.1 0.09 12.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) DUF3618 PF12277.6 MSTRG.2845.1_1 - 0.077 13.1 2.3 0.23 11.6 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) CHDCT2 PF08074.9 MSTRG.2845.1_1 - 0.33 11.0 12.4 0.24 11.4 1.8 3.2 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain Atg14 PF10186.7 MSTRG.2845.1_1 - 0.4 9.6 4.2 0.52 9.2 1.8 2.3 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.9 MSTRG.2845.1_1 - 0.43 10.7 0.0 0.43 10.7 0.0 3.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) PolyA_pol PF01743.18 MSTRG.2845.1_1 - 3.8 7.8 5.4 97 3.3 5.4 2.6 1 1 0 1 1 1 0 Poly A polymerase head domain Sec8_exocyst PF04048.12 MSTRG.2845.1_1 - 4.8 6.9 9.5 5.3 6.8 0.2 3.8 3 2 0 3 3 3 0 Sec8 exocyst complex component specific domain Fib_alpha PF08702.8 MSTRG.2845.1_1 - 7 6.7 18.4 3.5 7.7 3.2 4.6 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family DivIC PF04977.13 MSTRG.2845.1_1 - 8 6.2 8.5 16 5.2 0.0 4.2 5 0 0 5 5 5 0 Septum formation initiator FAM150 PF15129.4 MSTRG.131874.1_1 - 2.3e-07 30.9 0.0 5.3e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 FAM150 family Lipid_DES PF08557.8 MSTRG.90349.2_1 - 8.7e-10 37.8 0.2 1.3e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Ist1 PF03398.12 MSTRG.4259.2_1 - 4.8e-18 65.5 1.3 6e-18 65.1 1.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ist1 PF03398.12 MSTRG.4259.2_2 - 4.2e-27 94.9 0.0 5.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RRM_1 PF00076.20 MSTRG.133354.1_1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAP-gamma PF07074.10 MSTRG.46401.1_1 - 6.2e-85 282.8 6.1 7.3e-85 282.6 6.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) YopD PF05844.10 MSTRG.46401.1_1 - 0.0072 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 YopD protein Renin_r PF07850.12 MSTRG.46401.1_1 - 0.0093 16.4 0.4 0.15 12.5 0.3 2.1 2 0 0 2 2 2 1 Renin receptor-like protein DUF3270 PF11674.6 MSTRG.46401.1_1 - 0.019 15.0 0.1 0.037 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) zf-C4 PF00105.16 MSTRG.87022.1_1 - 1.8e-32 111.5 16.3 2.4e-32 111.1 16.3 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Exo_endo_phos_2 PF14529.4 MSTRG.120105.1_1 - 5e-07 29.5 0.1 1.7e-06 27.7 0.1 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.21 MSTRG.120105.1_1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Peptidase_S11 PF00768.18 MSTRG.48759.1_2 - 0.098 11.9 0.1 0.14 11.4 0.1 1.4 1 1 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Glypican PF01153.17 MSTRG.63694.1_2 - 3.1e-36 125.2 0.0 3.3e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Glypican EGF_2 PF07974.11 MSTRG.30775.1_2 - 9.6e-08 32.1 83.4 0.00049 20.3 13.0 5.6 5 1 0 5 5 5 4 EGF-like domain hEGF PF12661.5 MSTRG.30775.1_2 - 0.024 15.2 10.5 0.024 15.2 10.5 6.2 5 2 0 5 5 5 0 Human growth factor-like EGF Laminin_EGF PF00053.22 MSTRG.30775.1_2 - 0.041 13.9 61.1 2.1 8.4 20.9 4.4 1 1 3 4 4 4 0 Laminin EGF domain EGF PF00008.25 MSTRG.30775.1_2 - 0.088 13.0 9.7 0.088 13.0 9.7 5.9 6 1 1 7 7 7 0 EGF-like domain DSL PF01414.17 MSTRG.30775.1_2 - 1.1 9.4 56.1 0.11 12.6 13.4 3.8 3 1 0 3 3 3 0 Delta serrate ligand DUF1669 PF07894.10 MSTRG.23658.1_2 - 0.019 14.4 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) RhoGEF PF00621.18 MSTRG.29007.1_3 - 2.9e-28 99.2 1.0 6.6e-28 98.0 1.0 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.27 MSTRG.29007.1_3 - 1.5e-06 28.5 2.5 1.6e-05 25.2 2.5 2.4 1 1 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.3 MSTRG.29007.1_3 - 0.00021 21.2 0.1 0.00044 20.1 0.1 1.5 1 0 0 1 1 1 1 PH domain Phage_antiter_Q PF06323.9 MSTRG.29007.1_3 - 0.012 15.0 0.2 0.023 14.1 0.2 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q PH_10 PF15411.4 MSTRG.29007.1_3 - 0.02 15.0 0.4 0.064 13.4 0.4 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain SKA1 PF07160.10 MSTRG.29007.1_3 - 0.045 13.5 3.3 2.3 7.9 0.5 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Endotoxin_N PF03945.12 MSTRG.29007.1_3 - 0.16 11.6 2.8 0.076 12.6 0.5 1.6 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain LMBR1 PF04791.14 MSTRG.29007.1_3 - 0.22 10.2 3.1 0.13 11.0 0.8 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.144030.1_2 - 0.0058 16.7 0.0 0.0076 16.3 0.0 1.2 1 0 0 1 1 1 1 Transposase DUF3104 PF11302.6 MSTRG.24978.1_2 - 0.13 11.9 0.3 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.132039.1_3 - 6.3e-23 80.7 0.4 1.4e-22 79.5 0.4 1.6 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.4 MSTRG.132039.1_3 - 0.00069 19.2 3.1 0.0017 18.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.4 MSTRG.132039.1_3 - 0.0014 19.1 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_21 PF13276.4 MSTRG.132039.1_3 - 0.0031 17.5 0.3 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 HTH-like domain GcrA PF07750.9 MSTRG.132039.1_3 - 0.0072 16.6 0.1 0.012 15.9 0.1 1.3 1 0 0 1 1 1 1 GcrA cell cycle regulator DDE_Tnp_ISAZ013 PF07592.9 MSTRG.132039.1_3 - 0.086 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DUF1456 PF07308.11 MSTRG.132039.1_3 - 0.12 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Kelch_1 PF01344.23 MSTRG.24761.1_3 - 1.4e-06 27.7 0.1 2.3e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Kelch motif Glyoxal_oxid_N PF07250.9 MSTRG.24761.1_3 - 0.032 13.3 0.0 0.037 13.0 0.0 1.0 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Gal-bind_lectin PF00337.20 MSTRG.133528.2_3 - 3.9e-20 71.6 0.0 6e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin Folate_rec PF03024.12 MSTRG.133528.2_3 - 0.082 12.6 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Folate receptor family Bcl-2 PF00452.17 MSTRG.107860.1_2 - 2e-07 31.4 0.5 1.6e-06 28.5 0.3 2.0 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family RVT_1 PF00078.25 MSTRG.111552.1_2 - 3.8e-10 39.5 0.0 4.3e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Blt1 PF12754.5 MSTRG.45332.1_1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain Notch PF00066.15 MSTRG.142632.1_2 - 0.44 10.9 7.5 0.81 10.1 1.0 2.5 2 0 0 2 2 2 0 LNR domain PPP4R2 PF09184.9 MSTRG.58513.2_2 - 3 7.2 14.3 3.8 6.9 14.3 1.1 1 0 0 1 1 1 0 PPP4R2 CALM_bind PF16025.3 MSTRG.88998.1_2 - 3.5e-15 56.0 0.8 3.5e-15 56.0 0.8 1.8 1 1 1 2 2 2 1 Calcium-dependent calmodulin binding WASH-7_mid PF14744.4 MSTRG.88998.1_2 - 0.066 12.2 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 WAC_Acf1_DNA_bd PF10537.7 MSTRG.88998.1_2 - 0.22 11.9 1.3 4.5 7.7 1.3 2.2 1 1 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF1031 PF06275.9 MSTRG.97394.1_3 - 0.083 13.0 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DUF3847 PF12958.5 MSTRG.141315.1_2 - 0.2 11.7 0.2 0.29 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) OTU PF02338.17 MSTRG.141315.1_3 - 1.5e-28 99.7 0.1 3.5e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease BicD PF09730.7 MSTRG.109489.2_3 - 9.8e-119 397.7 18.1 1.1e-118 397.5 18.1 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF1759 PF03564.13 MSTRG.109489.2_3 - 0.0012 18.7 7.2 0.0028 17.5 7.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1759) ApoO PF09769.7 MSTRG.109489.2_3 - 0.015 15.1 1.6 0.048 13.5 0.6 2.1 1 1 1 2 2 2 0 Apolipoprotein O UvsY PF11056.6 MSTRG.109489.2_3 - 0.033 14.4 1.2 0.058 13.6 1.2 1.4 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY DUF1444 PF07285.9 MSTRG.109489.2_3 - 0.035 13.5 2.4 0.053 12.9 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) Spc7 PF08317.9 MSTRG.109489.2_3 - 0.052 12.3 14.3 0.07 11.9 13.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.10 MSTRG.109489.2_3 - 0.054 11.5 19.4 0.65 7.9 8.8 2.1 1 1 1 2 2 2 0 HOOK protein Rab5-bind PF09311.9 MSTRG.109489.2_3 - 0.087 12.1 19.4 0.022 14.0 8.3 2.3 1 1 0 2 2 2 0 Rabaptin-like protein Gp-FAR-1 PF05823.10 MSTRG.109489.2_3 - 0.12 12.6 8.9 0.18 12.0 7.8 2.0 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) APG6 PF04111.10 MSTRG.109489.2_3 - 0.16 11.2 13.6 0.24 10.6 13.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 HMMR_N PF15905.3 MSTRG.109489.2_3 - 0.18 11.1 20.4 0.054 12.8 9.9 2.1 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF1779 PF08680.8 MSTRG.109489.2_3 - 0.24 11.4 3.3 0.33 11.0 3.3 1.2 1 0 0 1 1 1 0 TATA-box binding Fib_alpha PF08702.8 MSTRG.109489.2_3 - 0.63 10.1 10.9 0.67 10.0 1.5 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FUSC PF04632.10 MSTRG.109489.2_3 - 1.2 7.5 8.7 1.5 7.2 8.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.23 MSTRG.109489.2_3 - 2 7.9 17.1 33 4.0 7.6 2.7 1 1 1 2 2 2 0 Syntaxin Reo_sigmaC PF04582.10 MSTRG.109489.2_3 - 2 7.6 5.4 12 5.1 0.7 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FlgN PF05130.10 MSTRG.109489.2_3 - 2 8.8 17.0 12 6.3 14.3 2.2 1 1 1 2 2 2 0 FlgN protein HIP1_clath_bdg PF16515.3 MSTRG.109489.2_3 - 2.7 8.5 21.2 8.1 7.0 7.9 2.6 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GLTP PF08718.9 MSTRG.109489.2_3 - 4.4 7.4 9.4 17 5.6 4.1 2.2 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) DUF2448 PF10476.7 MSTRG.98486.1_2 - 6.9e-18 65.2 0.0 8.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) PMP1_2 PF08114.9 MSTRG.98486.1_2 - 3.7 7.2 7.0 0.59 9.8 0.2 2.6 3 0 0 3 3 3 0 ATPase proteolipid family Pentaxin PF00354.15 MSTRG.116539.1_2 - 4.9e-55 186.1 0.5 5.6e-55 185.9 0.5 1.0 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.4 MSTRG.116539.1_2 - 2.8e-10 40.4 0.1 3.6e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF2949 PF11165.6 MSTRG.115305.1_1 - 0.19 11.9 0.6 0.39 10.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2949) Hexokinase_1 PF00349.19 MSTRG.91693.1_2 - 3.5e-118 392.5 1.1 4.7e-76 255.1 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_2 PF03727.14 MSTRG.91693.1_2 - 1.8e-87 292.6 1.3 2.3e-81 272.7 0.1 2.3 2 0 0 2 2 2 2 Hexokinase Sec23_trunk PF04811.13 MSTRG.57484.1_1 - 7.7e-09 35.3 0.0 9.3e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain RVT_1 PF00078.25 MSTRG.84594.1_1 - 1.2e-06 28.1 0.0 1.3e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PDZ PF00595.22 MSTRG.15770.1_1 - 3.3e-12 46.4 0.0 6.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 MSTRG.15770.1_1 - 0.00051 20.2 0.0 0.00092 19.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.3 MSTRG.15770.1_1 - 0.0012 19.8 0.9 0.0021 19.1 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) HTH_5 PF01022.18 MSTRG.15770.1_3 - 0.094 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family ELO PF01151.16 MSTRG.121600.2_2 - 1.4e-31 109.8 8.6 1.7e-31 109.6 8.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PKK PF12474.6 MSTRG.11999.1_2 - 0.00093 19.2 22.7 0.00093 19.2 22.7 3.5 1 1 1 2 2 2 1 Polo kinase kinase AAA-ATPase_like PF09820.7 MSTRG.11999.1_2 - 0.0019 17.6 5.2 0.0019 17.6 5.2 2.0 1 1 1 2 2 2 1 Predicted AAA-ATPase SWIRM PF04433.15 MSTRG.11999.1_2 - 0.4 10.9 3.9 0.27 11.4 0.4 2.4 1 1 0 2 2 2 0 SWIRM domain Ceramidase PF05875.10 MSTRG.39153.1_1 - 1e-12 47.9 0.1 1.4e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Ceramidase HTH_23 PF13384.4 MSTRG.3032.1_3 - 0.00023 20.7 0.2 0.00029 20.4 0.2 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.4 MSTRG.3032.1_3 - 0.0012 18.7 0.3 0.0014 18.5 0.3 1.1 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.10 MSTRG.3032.1_3 - 0.058 12.9 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 KH_1 PF00013.27 MSTRG.132206.1_2 - 2.1e-20 72.2 1.8 3.8e-20 71.4 1.8 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.15 MSTRG.132206.1_2 - 8.4e-05 22.2 0.5 8.4e-05 22.2 0.5 1.5 2 0 0 2 2 2 1 KH domain KH_5 PF13184.4 MSTRG.132206.1_2 - 0.043 13.8 0.2 0.043 13.8 0.2 1.5 2 0 0 2 2 2 0 NusA-like KH domain KH_4 PF13083.4 MSTRG.132206.1_2 - 0.29 10.9 1.3 0.49 10.2 0.7 1.6 1 1 1 2 2 2 0 KH domain PDZ PF00595.22 MSTRG.18092.1_2 - 3.4e-17 62.4 1.7 4.8e-17 61.9 1.7 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 MSTRG.18092.1_2 - 1.3e-05 25.3 0.2 2e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 PDZ domain Actin PF00022.17 MSTRG.18092.1_2 - 0.0011 17.5 0.1 0.44 9.0 0.0 2.0 2 0 0 2 2 2 2 Actin Tricorn_PDZ PF14685.4 MSTRG.18092.1_2 - 0.037 13.9 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain zf-H2C2_2 PF13465.4 MSTRG.131683.1_3 - 5.3e-55 181.4 78.0 2.9e-08 33.7 0.6 9.2 9 0 0 9 9 9 9 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.131683.1_3 - 2.8e-44 147.0 89.7 1.2e-06 28.5 1.0 10.1 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.131683.1_3 - 4.1e-24 83.1 82.0 0.0009 19.7 0.5 10.0 10 0 0 10 10 10 9 C2H2-type zinc finger zf-LYAR PF08790.9 MSTRG.131683.1_3 - 1.3e-08 34.5 65.5 0.029 14.1 0.3 9.3 9 0 0 9 9 9 6 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.3 MSTRG.131683.1_3 - 0.00066 19.2 65.5 0.25 11.0 2.1 8.8 9 0 0 9 9 9 5 zinc-finger C2H2-type Zn-ribbon_8 PF09723.8 MSTRG.131683.1_3 - 0.0059 16.6 1.4 0.0059 16.6 1.4 6.5 3 2 5 8 8 8 3 Zinc ribbon domain FAM178 PF14816.4 MSTRG.131683.1_3 - 0.0094 14.8 0.4 0.49 9.2 0.0 3.1 1 1 3 4 4 4 1 Family of unknown function, FAM178 BHD_1 PF10403.7 MSTRG.131683.1_3 - 0.035 13.8 5.3 9.7 6.0 0.0 4.8 6 1 1 7 7 7 0 Rad4 beta-hairpin domain 1 BDHCT_assoc PF16204.3 MSTRG.131683.1_3 - 0.038 13.5 6.7 0.15 11.6 2.3 2.7 1 1 1 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein zf-C2H2_jaz PF12171.6 MSTRG.131683.1_3 - 0.048 13.8 0.1 1 9.6 0.1 8.1 9 0 0 9 9 8 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 MSTRG.131683.1_3 - 0.15 11.9 0.1 0.15 11.9 0.1 9.8 11 1 0 11 11 9 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.3 MSTRG.131683.1_3 - 0.21 12.2 31.8 1.2 9.7 0.3 4.7 3 1 2 5 5 5 0 zinc-ribbon family zf-met PF12874.5 MSTRG.131683.1_3 - 0.3 11.4 0.3 0.1 12.9 2.1 8.2 10 0 0 10 10 9 0 Zinc-finger of C2H2 type HypA PF01155.17 MSTRG.131683.1_3 - 1.6 8.6 30.5 12 5.8 7.4 4.4 1 1 0 2 2 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-trcl PF13451.4 MSTRG.131683.1_3 - 6.8 6.5 43.8 8.3 6.3 0.1 7.5 8 0 0 8 8 8 0 Probable zinc-ribbon domain DDE_3 PF13358.4 MSTRG.99784.1_3 - 0.00023 20.8 0.1 0.00031 20.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Apt1 PF10351.7 MSTRG.85279.1_2 - 1.9e-05 23.6 6.1 2.1e-05 23.5 6.1 1.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain CDP-OH_P_transf PF01066.19 MSTRG.85279.1_2 - 0.26 12.0 0.9 0.51 11.0 0.9 1.5 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase SPX PF03105.17 MSTRG.85279.1_2 - 1.1 9.0 16.9 1.3 8.7 16.9 1.0 1 0 0 1 1 1 0 SPX domain NPR3 PF03666.11 MSTRG.85279.1_2 - 3.3 6.3 11.3 4.3 5.9 11.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PH PF00169.27 MSTRG.133471.1_1 - 2.4e-09 37.5 0.9 2.5e-09 37.4 0.9 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 MSTRG.133471.1_1 - 0.00094 19.4 1.9 0.0012 19.2 1.9 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain HemX PF04375.12 MSTRG.133471.1_1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase HORMA PF02301.16 MSTRG.97343.1_2 - 2.5e-08 33.6 0.1 3.5e-08 33.1 0.1 1.3 1 1 0 1 1 1 1 HORMA domain Acetyltransf_1 PF00583.23 MSTRG.7904.2_1 - 6.5e-14 52.0 0.0 8.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.5 MSTRG.7904.2_1 - 1.8e-09 37.7 0.1 2.7e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.5 MSTRG.7904.2_1 - 1.1e-08 35.0 0.1 1.5e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.5 MSTRG.7904.2_1 - 3e-06 27.4 0.5 4.9e-06 26.7 0.4 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.8 MSTRG.7904.2_1 - 0.00029 20.6 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.5 MSTRG.7904.2_1 - 0.0078 16.2 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.4 MSTRG.7904.2_1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.5 MSTRG.7904.2_1 - 0.052 14.1 0.0 0.075 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_7N PF13733.4 MSTRG.63853.1_2 - 5.7e-06 25.9 0.0 8.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 LRR_6 PF13516.4 MSTRG.83424.1_3 - 0.0018 18.1 0.4 0.24 11.4 0.1 3.3 3 0 0 3 3 3 1 Leucine Rich repeat MSG PF02349.13 MSTRG.4966.1_3 - 0.00034 20.6 1.0 0.35 11.0 0.1 2.2 1 1 1 2 2 2 2 Major surface glycoprotein Chitin_bind_1 PF00187.17 MSTRG.4966.1_3 - 0.5 10.8 22.9 1.1e+02 3.2 8.2 4.1 1 1 1 2 2 2 0 Chitin recognition protein IPK PF03770.14 MSTRG.8050.1_2 - 3.8e-28 98.6 1.2 8.3e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase RVT_1 PF00078.25 MSTRG.127525.1_3 - 3.7e-09 36.3 0.1 4.5e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.15 MSTRG.81556.1_2 - 6.2e-117 389.4 0.0 3.6e-82 275.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.23 MSTRG.81556.1_2 - 8.3e-59 199.0 0.0 1.2e-45 155.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.21 MSTRG.81556.1_2 - 0.0064 16.3 0.0 0.31 10.8 0.0 3.0 3 1 1 4 4 4 1 Phosphotransferase enzyme family RIO1 PF01163.20 MSTRG.81556.1_2 - 0.02 14.4 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.23 MSTRG.40803.1_2 - 0.014 14.6 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain UPF0552 PF10574.7 MSTRG.72328.2_2 - 1.1e-93 312.5 0.4 1.4e-93 312.1 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0552 FAM131 PF15010.4 MSTRG.119347.1_3 - 4e-09 36.6 0.0 4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Putative cell signalling Exo_endo_phos_2 PF14529.4 MSTRG.42818.1_1 - 0.0022 17.7 0.1 0.0026 17.5 0.1 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HAMP PF00672.23 MSTRG.47587.1_3 - 0.11 12.7 0.3 12 6.1 0.1 2.1 2 0 0 2 2 2 0 HAMP domain YojJ PF10372.7 MSTRG.113729.1_1 - 0.011 15.6 0.4 0.019 14.9 0.4 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus OmpH PF03938.12 MSTRG.113729.1_1 - 0.022 14.6 1.6 0.022 14.6 1.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3373 PF11853.6 MSTRG.113729.1_1 - 0.038 12.6 0.6 0.036 12.7 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) SlyX PF04102.10 MSTRG.113729.1_1 - 0.049 14.1 2.1 0.074 13.5 2.1 1.4 1 0 0 1 1 1 0 SlyX IncA PF04156.12 MSTRG.113729.1_1 - 0.093 12.4 4.2 0.089 12.4 4.2 1.1 1 0 0 1 1 1 0 IncA protein DUF2621 PF11084.6 MSTRG.17323.1_2 - 3.9 7.3 4.7 0.51 10.2 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2621) A2M_recep PF07677.12 MSTRG.35889.1_2 - 1.5e-17 64.0 0.3 2.1e-17 63.5 0.3 1.2 1 0 0 1 1 1 1 A-macroglobulin receptor I-set PF07679.14 MSTRG.97347.1_2 - 4.4e-14 52.2 0.0 5.1e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.97347.1_2 - 2.2e-11 44.1 0.0 2.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.97347.1_2 - 1.2e-10 41.2 0.1 1.5e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.97347.1_2 - 7.8e-08 32.4 0.0 9.6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 MSTRG.97347.1_2 - 6.3e-07 29.4 0.3 0.015 15.3 0.0 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_4 PF16680.3 MSTRG.97347.1_2 - 0.0041 17.3 0.8 0.018 15.3 0.8 1.8 1 1 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain BNR_assoc_N PF14873.4 MSTRG.97347.1_2 - 0.034 13.7 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase Izumo-Ig PF16706.3 MSTRG.97347.1_2 - 0.052 13.5 0.1 0.17 11.8 0.1 1.8 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain Actin PF00022.17 MSTRG.7671.1_1 - 3.3e-149 496.8 0.0 8.8e-149 495.4 0.0 1.6 1 1 0 1 1 1 1 Actin Archease PF01951.14 MSTRG.54750.1_1 - 1.2e-42 145.3 0.1 1.6e-42 144.9 0.1 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) RAI16-like PF10257.7 MSTRG.58905.1_2 - 2.8e-37 128.3 0.6 3.5e-37 128.0 0.6 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF2761 PF10959.6 MSTRG.25940.1_1 - 0.14 12.2 0.1 9.6 6.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2761) Curlin_rpt PF07012.10 MSTRG.47949.2_2 - 0.29 11.0 5.8 5.4 7.0 1.5 2.5 2 0 0 2 2 2 0 Curlin associated repeat Curlin_rpt PF07012.10 MSTRG.47949.2_3 - 0.064 13.2 10.4 2.8 7.9 0.1 3.6 2 1 1 3 3 3 0 Curlin associated repeat RecR PF02132.13 MSTRG.144347.1_2 - 0.61 9.6 6.8 4.2 6.9 6.8 2.2 1 1 0 1 1 1 0 RecR protein Laminin_N PF00055.15 MSTRG.42256.1_3 - 1e-60 205.2 0.0 1e-60 205.2 0.0 2.9 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.22 MSTRG.42256.1_3 - 2.2e-25 88.4 52.8 2e-09 37.3 12.5 3.3 3 0 0 3 3 3 3 Laminin EGF domain F5_F8_type_C PF00754.23 MSTRG.42256.1_3 - 0.00062 19.7 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Drf_FH3 PF06367.14 MSTRG.57906.1_2 - 1.9e-18 66.6 7.0 2.3e-18 66.4 7.0 1.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF4201 PF13870.4 MSTRG.57906.1_2 - 0.0021 17.6 8.8 0.0022 17.5 8.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Terpene_synth_C PF03936.14 MSTRG.57906.1_2 - 0.0031 16.8 0.9 0.0042 16.4 0.9 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain T4SS PF07996.9 MSTRG.57906.1_2 - 0.0065 16.8 1.6 0.008 16.5 1.6 1.0 1 0 0 1 1 1 1 Type IV secretion system proteins DUF1342 PF07072.9 MSTRG.57906.1_2 - 0.012 15.3 5.1 0.013 15.1 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) YvfG PF09628.8 MSTRG.57906.1_2 - 0.026 14.7 0.4 0.082 13.1 0.1 1.9 1 1 1 2 2 2 0 YvfG protein FlgN PF05130.10 MSTRG.57906.1_2 - 0.029 14.7 5.6 0.039 14.3 5.6 1.3 1 1 0 1 1 1 0 FlgN protein zf-DNA_Pol PF08996.8 MSTRG.57906.1_2 - 0.037 13.7 1.5 0.042 13.5 1.5 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Cob_adeno_trans PF01923.16 MSTRG.57906.1_2 - 0.039 14.0 1.7 0.051 13.6 1.7 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Mei5 PF10376.7 MSTRG.57906.1_2 - 0.049 13.4 6.2 0.058 13.1 6.2 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein Ead_Ea22 PF13935.4 MSTRG.57906.1_2 - 0.053 14.1 4.9 0.063 13.8 4.9 1.1 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF947 PF06102.10 MSTRG.57906.1_2 - 0.086 12.7 4.1 0.11 12.3 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF947) APG6 PF04111.10 MSTRG.57906.1_2 - 0.089 12.0 6.0 0.097 11.9 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.11 MSTRG.57906.1_2 - 0.19 11.3 7.2 0.27 10.9 7.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fe-ADH_2 PF13685.4 MSTRG.57906.1_2 - 0.2 11.1 1.3 0.23 11.0 1.3 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase BST2 PF16716.3 MSTRG.57906.1_2 - 0.25 11.8 7.7 0.086 13.3 3.7 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 AAA_32 PF13654.4 MSTRG.57906.1_2 - 0.43 9.2 8.5 0.3 9.7 4.9 1.8 1 1 1 2 2 2 0 AAA domain XhlA PF10779.7 MSTRG.57906.1_2 - 0.92 9.6 4.5 0.48 10.5 2.3 1.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF972 PF06156.11 MSTRG.57906.1_2 - 1.1 9.8 7.8 1.4 9.4 6.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PUA PF01472.18 MSTRG.135590.1_2 - 1.3e-19 69.8 0.1 2e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 PUA domain Methyltr_RsmF_N PF17125.3 MSTRG.135590.1_2 - 0.12 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF HALZ PF02183.16 MSTRG.12946.1_1 - 0.34 11.0 3.5 0.54 10.4 3.5 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper SSP160 PF06933.9 MSTRG.7811.1_2 - 0.049 11.7 10.0 0.048 11.7 10.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3275 PF11679.6 MSTRG.7811.1_2 - 2 8.2 4.8 2.3 8.0 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Sporozoite_P67 PF05642.9 MSTRG.7811.1_2 - 8.6 4.2 8.2 9 4.1 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Calpain_inhib PF00748.17 MSTRG.7811.1_3 - 0.092 13.1 2.1 0.096 13.0 2.1 1.0 1 0 0 1 1 1 0 Calpain inhibitor Cation_ATPase_N PF00690.24 MSTRG.133443.3_1 - 9.7e-15 53.9 0.0 1.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus CP2 PF04516.13 MSTRG.110534.1_2 - 1.5e-16 60.3 0.0 1.7e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 CP2 transcription factor Ribosomal_S17e PF00833.16 MSTRG.86082.1_3 - 7.7e-70 232.4 0.6 1e-69 232.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal S17 TMEM108 PF15759.3 MSTRG.11497.1_3 - 2.4e-87 293.8 0.8 2.8e-87 293.6 0.8 1.0 1 0 0 1 1 1 1 TMEM108 family UPAR_LY6 PF00021.19 MSTRG.143013.1_2 - 0.00013 22.5 13.3 0.00018 22.0 13.3 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.19 MSTRG.143013.1_2 - 0.34 11.0 14.3 0.51 10.5 14.3 1.3 1 0 0 1 1 1 0 Snake toxin DDE_3 PF13358.4 MSTRG.69978.1_3 - 0.003 17.2 0.0 0.0034 17.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease STAT_alpha PF01017.18 MSTRG.104680.1_2 - 3.5e-10 39.9 1.2 3.9e-10 39.7 1.2 1.1 1 0 0 1 1 1 1 STAT protein, all-alpha domain DUF4287 PF14117.4 MSTRG.132673.1_1 - 0.046 13.7 0.5 0.061 13.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) PX PF00787.22 MSTRG.132673.1_2 - 0.044 13.6 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 PX domain TMEM52 PF14979.4 MSTRG.111896.1_3 - 0.48 10.2 2.4 0.67 9.7 2.4 1.1 1 0 0 1 1 1 0 Transmembrane 52 zf-SCNM1 PF15803.3 MSTRG.82782.1_2 - 0.031 13.8 1.1 0.11 12.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 DDE_3 PF13358.4 MSTRG.128902.1_2 - 0.00012 21.8 0.1 0.00014 21.5 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PX PF00787.22 MSTRG.35277.1_1 - 3e-18 65.7 0.2 3.8e-18 65.4 0.2 1.1 1 0 0 1 1 1 1 PX domain RVT_1 PF00078.25 MSTRG.48.1_1 - 5.1e-09 35.8 0.0 5.5e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helo_like_N PF17111.3 MSTRG.124650.1_2 - 0.0061 15.8 1.0 0.0062 15.8 1.0 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Sec8_exocyst PF04048.12 MSTRG.124650.1_2 - 0.007 16.2 2.0 0.008 16.0 2.0 1.1 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain MbeD_MobD PF04899.10 MSTRG.124650.1_2 - 0.0087 16.0 0.3 0.012 15.6 0.3 1.2 1 0 0 1 1 1 1 MbeD/MobD like T3SSipB PF16535.3 MSTRG.124650.1_2 - 0.022 15.1 2.9 0.025 14.9 2.9 1.0 1 0 0 1 1 1 0 Type III cell invasion protein SipB BST2 PF16716.3 MSTRG.124650.1_2 - 0.027 14.9 4.4 0.048 14.1 1.4 2.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.6 MSTRG.124650.1_2 - 0.028 14.3 7.4 0.042 13.7 7.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc42p PF11544.6 MSTRG.124650.1_2 - 0.029 14.2 3.2 0.12 12.3 3.2 1.8 1 1 0 1 1 1 0 Spindle pole body component Spc42p DUF724 PF05266.12 MSTRG.124650.1_2 - 0.043 13.5 1.9 0.045 13.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fez1 PF06818.13 MSTRG.124650.1_2 - 0.044 14.1 4.3 0.049 13.9 4.3 1.0 1 0 0 1 1 1 0 Fez1 SlyX PF04102.10 MSTRG.124650.1_2 - 0.06 13.9 0.9 0.42 11.1 0.9 2.0 1 1 0 1 1 1 0 SlyX bZIP_1 PF00170.19 MSTRG.124650.1_2 - 0.066 13.2 3.9 1.1 9.2 0.5 2.2 2 0 0 2 2 2 0 bZIP transcription factor Mnd1 PF03962.13 MSTRG.124650.1_2 - 0.16 11.7 4.3 0.17 11.6 4.3 1.1 1 0 0 1 1 1 0 Mnd1 family TMPIT PF07851.11 MSTRG.124650.1_2 - 0.75 8.8 3.9 0.81 8.7 3.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein Ig_3 PF13927.4 MSTRG.65095.1_2 - 9.4e-10 38.8 0.2 1.5e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.65095.1_2 - 1.4e-08 34.8 0.1 1.8e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.65095.1_2 - 5.1e-07 29.6 0.5 7.9e-06 25.8 0.5 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Podoplanin PF05808.9 MSTRG.65095.1_2 - 0.00019 21.5 2.5 0.0002 21.4 2.5 1.2 1 0 0 1 1 1 1 Podoplanin I-set PF07679.14 MSTRG.65095.1_2 - 0.00045 20.1 0.7 0.0031 17.4 0.7 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_4 PF16680.3 MSTRG.65095.1_2 - 0.026 14.7 0.1 0.035 14.3 0.1 1.2 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain VSP PF03302.11 MSTRG.65095.1_2 - 0.084 11.6 2.5 0.084 11.6 2.5 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein B1 PF02246.13 MSTRG.65095.1_2 - 0.086 12.8 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein L b1 domain DUF3318 PF11780.6 MSTRG.52572.1_1 - 0.021 14.6 0.1 0.027 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Phage_fiber PF03335.11 MSTRG.69694.1_3 - 4.8 7.5 10.1 7.2 6.9 1.6 2.3 1 1 1 2 2 2 0 Phage tail fibre repeat VWA PF00092.26 MSTRG.128322.1_1 - 0.028 14.6 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain PGA2 PF07543.10 MSTRG.91894.1_1 - 0.071 12.9 0.8 9.8 6.0 0.1 2.4 3 0 0 3 3 3 0 Protein trafficking PGA2 PGA2 PF07543.10 MSTRG.91894.1_2 - 0.032 14.1 0.3 24 4.8 0.0 2.9 3 0 0 3 3 3 0 Protein trafficking PGA2 MF_alpha PF04648.10 MSTRG.91894.1_2 - 0.86 9.9 16.5 8.2 6.8 1.0 3.3 3 0 0 3 3 3 0 Yeast mating factor alpha hormone PGA2 PF07543.10 MSTRG.91894.1_3 - 0.18 11.7 0.3 21 4.9 0.0 2.5 3 0 0 3 3 3 0 Protein trafficking PGA2 MF_alpha PF04648.10 MSTRG.91894.1_3 - 9.4 6.6 14.2 10 6.5 1.1 3.2 3 0 0 3 3 3 0 Yeast mating factor alpha hormone HSBP1 PF06825.10 MSTRG.62538.1_1 - 0.0038 17.0 0.4 0.012 15.4 0.4 1.9 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Transposase_22 PF02994.12 MSTRG.62538.1_1 - 0.018 13.8 4.1 0.055 12.2 4.2 1.6 1 1 1 2 2 2 0 L1 transposable element CCDC-167 PF15188.4 MSTRG.62538.1_1 - 0.2 11.9 4.0 0.89 9.8 3.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 YWFCY PF14293.4 MSTRG.41537.1_1 - 0.11 12.7 0.3 0.29 11.3 0.2 1.6 1 1 1 2 2 2 0 YWFCY protein B12D PF06522.9 MSTRG.56420.1_3 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit MRP-L28 PF09812.7 MSTRG.23468.1_1 - 1.3e-08 35.0 0.2 2e-08 34.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 MFS_1 PF07690.14 MSTRG.43623.5_1 - 9.4e-18 64.1 3.1 1.1e-17 63.9 3.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.22 MSTRG.43623.5_1 - 7e-10 38.2 0.3 7.7e-10 38.1 0.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.11 MSTRG.43623.5_1 - 0.012 14.0 0.6 0.018 13.4 0.4 1.4 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Deltameth_res PF16020.3 MSTRG.43623.5_1 - 0.17 11.6 0.1 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Deltamethrin resistance WHIM1 PF15612.4 MSTRG.95388.1_2 - 0.097 12.1 0.1 0.097 12.1 0.1 1.6 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 RRM_5 PF13893.4 MSTRG.12118.1_1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1633 PF07794.9 MSTRG.74869.1_2 - 0.096 10.7 4.1 0.1 10.6 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) zf-tcix PF14952.4 MSTRG.139333.1_2 - 8.4 6.0 12.2 9.3 5.8 0.5 3.1 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding EGF PF00008.25 MSTRG.82837.1_2 - 4.1e-05 23.7 11.3 4.1e-05 23.7 11.3 5.2 5 0 0 5 5 5 1 EGF-like domain hEGF PF12661.5 MSTRG.82837.1_2 - 0.0005 20.5 9.6 0.0005 20.5 9.6 6.0 5 2 1 6 6 6 1 Human growth factor-like EGF EGF_2 PF07974.11 MSTRG.82837.1_2 - 0.0025 18.0 38.0 0.014 15.6 15.8 5.2 4 1 1 5 5 5 2 EGF-like domain Laminin_EGF PF00053.22 MSTRG.82837.1_2 - 0.0033 17.4 13.1 0.0033 17.4 13.1 3.9 1 1 3 4 4 4 2 Laminin EGF domain TMEM234 PF10639.7 MSTRG.4529.1_3 - 0.043 13.7 1.4 0.053 13.4 1.4 1.1 1 0 0 1 1 1 0 Putative transmembrane family 234 RNase_H PF00075.22 MSTRG.140132.1_3 - 0.064 13.3 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 RNase H TRIQK PF15168.4 MSTRG.39035.1_2 - 0.031 14.0 0.5 0.042 13.6 0.5 1.2 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family UPF0560 PF10577.7 MSTRG.39035.1_2 - 1.6 7.0 4.2 1.9 6.7 4.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neurokinin_B PF03823.12 MSTRG.39035.1_2 - 3.6 7.5 7.0 14 5.6 0.9 2.2 2 0 0 2 2 2 0 Neurokinin B Nucleoside_tran PF01733.16 MSTRG.123363.1_3 - 1e-12 47.9 0.4 1.2e-12 47.7 0.4 1.0 1 0 0 1 1 1 1 Nucleoside transporter DUF2418 PF10332.7 MSTRG.37954.1_2 - 5.9 7.4 9.6 3.6 8.0 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2418) Spectrin PF00435.19 MSTRG.106999.1_3 - 5.7e-08 33.1 5.6 0.00013 22.2 0.6 2.3 2 0 0 2 2 2 2 Spectrin repeat Vip3A_N PF12495.6 MSTRG.106999.1_3 - 0.14 11.9 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Peptidase_M1 PF01433.18 MSTRG.72331.1_2 - 3.9e-39 134.9 0.8 1.6e-38 132.9 0.8 1.7 1 1 0 1 1 1 1 Peptidase family M1 BST2 PF16716.3 MSTRG.67430.1_1 - 0.0017 18.8 8.2 0.0056 17.1 1.2 2.4 2 0 0 2 2 2 2 Bone marrow stromal antigen 2 CENP-B_N PF04218.11 MSTRG.67430.1_1 - 0.0074 15.8 0.3 0.1 12.1 0.2 2.5 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain DASH_Dad2 PF08654.8 MSTRG.67430.1_1 - 0.0097 16.2 0.4 0.24 11.7 0.0 2.4 1 1 1 2 2 2 1 DASH complex subunit Dad2 TTSSLRR PF12468.6 MSTRG.67430.1_1 - 0.056 13.6 0.2 0.13 12.4 0.2 1.6 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein C9orf72-like PF15019.4 MSTRG.64030.1_2 - 1.8e-13 50.5 0.0 2.1e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 C9orf72-like protein family DUF5301 PF17225.1 MSTRG.64757.1_1 - 0.082 12.5 1.3 0.096 12.3 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) UFC1 PF08694.9 MSTRG.64757.1_1 - 0.2 11.2 0.8 0.23 11.0 0.8 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 MIF4G_like_2 PF09090.9 MSTRG.64757.1_1 - 0.23 10.8 8.8 0.25 10.6 8.8 1.0 1 0 0 1 1 1 0 MIF4G like APG6 PF04111.10 MSTRG.64757.1_1 - 3 7.0 15.0 3.1 7.0 15.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 PA26 PF04636.11 MSTRG.64757.1_1 - 3.6 6.3 10.2 3.7 6.2 10.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.4 MSTRG.64757.1_1 - 4.6 6.4 8.6 4.8 6.3 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bap31 PF05529.10 MSTRG.64757.1_1 - 6.7 6.1 11.7 7.7 5.9 11.7 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like zf-HIT PF04438.14 MSTRG.113483.1_1 - 3.1 7.6 17.0 5.9 6.7 0.1 4.2 4 1 0 4 4 4 0 HIT zinc finger zf-ANAPC11 PF12861.5 MSTRG.113483.1_1 - 3.9 7.5 10.5 3.6 7.6 8.7 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger p25-alpha PF05517.10 MSTRG.93410.1_3 - 0.13 12.3 0.2 0.14 12.1 0.2 1.1 1 0 0 1 1 1 0 p25-alpha TAP35_44 PF07265.9 MSTRG.64436.1_1 - 0.36 10.7 3.4 0.63 9.9 3.4 1.6 1 1 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 PD40 PF07676.10 MSTRG.108799.4_3 - 0.11 12.4 6.3 2.4 8.1 0.4 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat HTH_Tnp_Tc3_2 PF01498.16 MSTRG.54070.1_2 - 4.7e-12 45.8 3.2 8.3e-12 45.1 1.0 2.2 1 1 2 3 3 3 1 Transposase SUIM_assoc PF16619.3 MSTRG.54070.1_2 - 0.098 12.6 2.4 0.16 12.0 2.4 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Trypsin PF00089.24 MSTRG.138409.2_1 - 5.2e-29 101.5 8.5 7e-29 101.1 8.5 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 MSTRG.138409.2_1 - 5.5e-08 33.1 0.1 9.7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF4951 PF16309.3 MSTRG.138409.2_1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Domian of unknown function (DUF4951) DUF1330 PF07045.9 MSTRG.90116.1_1 - 0.35 11.1 2.8 6.6 7.0 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) MIB_HERC2 PF06701.11 MSTRG.90116.1_1 - 8.8 6.5 7.6 0.84 9.8 1.0 2.5 3 0 0 3 3 3 0 Mib_herc2 RVT_1 PF00078.25 MSTRG.99390.1_3 - 0.046 13.1 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 MSTRG.58810.1_3 - 1.7e-05 24.4 0.1 1.9e-05 24.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAM_decarbox PF01536.14 MSTRG.63581.1_2 - 3.5e-47 161.0 0.2 4.4e-47 160.7 0.2 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Claudin_3 PF06653.9 MSTRG.8994.1_1 - 0.028 14.2 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like MRP_L53 PF10780.7 MSTRG.45785.2_2 - 2.2e-05 24.4 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 MRP_L53 PF10780.7 MSTRG.45785.2_3 - 0.074 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 Tfb5 PF06331.10 MSTRG.121469.1_2 - 5.2e-27 93.6 0.4 7.4e-27 93.1 0.4 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 CDC4_D PF16856.3 MSTRG.100756.1_2 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain eIF-5_eIF-2B PF01873.15 MSTRG.117116.2_1 - 6e-34 116.3 1.0 6e-34 116.3 1.0 1.9 3 0 0 3 3 3 1 Domain found in IF2B/IF5 W2 PF02020.16 MSTRG.117116.2_1 - 2.2e-22 78.8 1.1 6.3e-22 77.4 1.1 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Carn_acyltransf PF00755.18 MSTRG.50668.1_3 - 2.1e-25 89.3 0.0 2.3e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3037 PF11236.6 MSTRG.50668.1_3 - 0.064 13.6 0.0 0.071 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) FAD-oxidase_C PF02913.17 MSTRG.50668.1_3 - 0.092 12.2 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Peptidase_A21 PF03566.11 MSTRG.91625.1_1 - 0.12 10.5 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Peptidase family A21 GETHR PF05671.9 MSTRG.77065.1_1 - 0.023 13.9 1.4 0.046 13.0 1.4 1.4 1 0 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) Kinetochor_Ybp2 PF08568.8 MSTRG.77065.1_3 - 2.1e-37 128.8 1.0 2.4e-37 128.6 1.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-met PF12874.5 MSTRG.12153.2_1 - 0.0033 17.6 4.2 0.0095 16.2 4.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 MSTRG.12153.2_1 - 0.022 14.9 1.6 0.048 13.9 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TRAM_LAG1_CLN8 PF03798.14 MSTRG.1646.1_3 - 2e-20 73.2 18.3 2e-20 73.2 18.3 1.7 2 0 0 2 2 2 1 TLC domain DDE_3 PF13358.4 MSTRG.64869.1_2 - 1.7e-07 31.0 1.7 1.8e-07 30.9 1.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease AIMP2_LysRS_bd PF16780.3 MSTRG.68758.1_1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain Auts2 PF15336.4 MSTRG.49517.1_2 - 0.0056 16.7 4.3 0.0069 16.4 4.3 1.1 1 0 0 1 1 1 1 Autism susceptibility gene 2 protein DUF3915 PF13054.4 MSTRG.49517.1_2 - 0.0079 16.0 9.6 0.01 15.7 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) PRIMA1 PF16101.3 MSTRG.49517.1_2 - 0.57 10.1 3.7 0.78 9.6 3.7 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ABC_membrane PF00664.21 MSTRG.129894.1_1 - 1.6e-09 37.7 1.5 1.9e-09 37.5 1.5 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region PI3K_P85_iSH2 PF16454.3 MSTRG.116529.1_1 - 6.5e-55 185.0 12.6 7.3e-55 184.8 12.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4201 PF13870.4 MSTRG.116529.1_1 - 0.026 14.0 9.8 0.037 13.5 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) WXG100 PF06013.10 MSTRG.116529.1_1 - 0.061 13.4 2.6 3.4 7.8 0.6 2.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG BRE1 PF08647.9 MSTRG.116529.1_1 - 0.07 13.1 5.5 1.4 8.9 0.1 2.7 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.9 MSTRG.116529.1_1 - 0.076 11.7 9.1 0.044 12.5 4.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2203 PF09969.7 MSTRG.116529.1_1 - 0.11 13.1 3.5 0.85 10.2 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Mod_r PF07200.11 MSTRG.116529.1_1 - 0.16 12.0 11.4 0.61 10.1 0.6 2.2 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.13 MSTRG.116529.1_1 - 0.65 9.4 4.4 0.85 9.0 4.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Hrs_helical PF12210.6 MSTRG.116529.1_1 - 4 7.9 8.0 16 6.0 1.8 2.5 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Occludin_ELL PF07303.11 MSTRG.116529.1_1 - 5 7.7 12.7 14 6.3 0.6 2.4 1 1 1 2 2 2 0 Occludin homology domain IncA PF04156.12 MSTRG.116529.1_1 - 5.4 6.6 14.9 3.1e+02 0.9 14.9 2.0 1 1 0 1 1 1 0 IncA protein FH2 PF02181.21 MSTRG.91918.1_2 - 8e-30 104.1 0.7 8.7e-30 103.9 0.7 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Hamartin PF04388.10 MSTRG.49810.1_1 - 0.39 9.2 0.9 0.45 9.0 0.9 1.0 1 0 0 1 1 1 0 Hamartin protein Sec7 PF01369.18 MSTRG.24230.1_2 - 7.4e-59 198.4 0.3 8.1e-59 198.3 0.3 1.0 1 0 0 1 1 1 1 Sec7 domain RCDG1 PF15725.3 MSTRG.86675.1_1 - 0.028 14.7 2.7 0.03 14.6 2.7 1.1 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Pkinase_Tyr PF07714.15 MSTRG.116652.1_3 - 0.0021 17.2 0.0 0.0022 17.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase End3 PF12761.5 MSTRG.93346.1_1 - 0.00014 22.0 5.6 0.39 10.7 3.6 2.4 1 1 2 3 3 3 2 Actin cytoskeleton-regulatory complex protein END3 DUF4763 PF15960.3 MSTRG.93346.1_1 - 0.0062 15.7 7.0 0.0062 15.7 7.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) Herpes_UL25 PF01499.14 MSTRG.93346.1_1 - 0.0089 14.5 1.4 0.011 14.1 1.4 1.1 1 0 0 1 1 1 1 Herpesvirus UL25 family IncA PF04156.12 MSTRG.93346.1_1 - 0.009 15.7 10.4 0.21 11.2 8.8 2.3 2 0 0 2 2 2 1 IncA protein DivIC PF04977.13 MSTRG.93346.1_1 - 0.011 15.3 12.2 1.1 8.9 0.9 3.2 2 1 1 3 3 3 0 Septum formation initiator Jnk-SapK_ap_N PF09744.7 MSTRG.93346.1_1 - 0.013 15.6 7.5 0.013 15.6 7.5 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Taxilin PF09728.7 MSTRG.93346.1_1 - 0.016 14.4 8.8 0.023 13.8 6.1 1.9 2 0 0 2 2 2 0 Myosin-like coiled-coil protein ADIP PF11559.6 MSTRG.93346.1_1 - 0.019 14.9 6.0 0.019 14.9 6.0 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3734 PF12536.6 MSTRG.93346.1_1 - 0.021 15.0 2.8 0.045 14.0 2.8 1.5 1 0 0 1 1 1 0 Patatin phospholipase Allexi_40kDa PF05549.9 MSTRG.93346.1_1 - 0.023 14.1 1.9 0.027 13.8 1.9 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein IFP_35_N PF07334.11 MSTRG.93346.1_1 - 0.029 14.3 3.8 8.1 6.5 0.0 3.2 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus LPP PF04728.11 MSTRG.93346.1_1 - 0.041 14.1 3.8 1.7 9.0 1.3 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Spc7 PF08317.9 MSTRG.93346.1_1 - 0.098 11.4 10.4 0.12 11.1 5.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.7 MSTRG.93346.1_1 - 0.12 11.1 3.6 0.15 10.8 3.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF724 PF05266.12 MSTRG.93346.1_1 - 0.14 11.8 8.7 0.06 13.0 6.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4718 PF15842.3 MSTRG.93346.1_1 - 0.15 11.7 2.3 0.21 11.2 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF4407 PF14362.4 MSTRG.93346.1_1 - 0.38 9.9 4.7 0.57 9.3 4.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.10 MSTRG.93346.1_1 - 0.69 10.2 10.8 0.69 10.2 7.0 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CHD5 PF04420.12 MSTRG.93346.1_1 - 0.98 9.1 4.5 0.44 10.3 0.8 2.0 1 1 1 2 2 2 0 CHD5-like protein DUF4200 PF13863.4 MSTRG.93346.1_1 - 1.1 9.5 12.4 24 5.2 11.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Occludin_ELL PF07303.11 MSTRG.93346.1_1 - 1.3 9.7 6.4 18 6.0 1.2 2.7 2 1 1 3 3 3 0 Occludin homology domain APG6 PF04111.10 MSTRG.93346.1_1 - 1.4 8.2 7.8 0.22 10.7 4.3 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 FlaC_arch PF05377.9 MSTRG.93346.1_1 - 1.9 8.8 8.8 17 5.8 2.6 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.4 MSTRG.93346.1_1 - 2 7.6 11.7 6.7 5.9 8.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) Bap31 PF05529.10 MSTRG.93346.1_1 - 2.1 7.8 8.3 3.4 7.1 7.7 1.6 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Tropomyosin_1 PF12718.5 MSTRG.93346.1_1 - 2.8 7.9 15.0 3.4 7.6 8.8 2.8 2 1 1 3 3 3 0 Tropomyosin like DUF1192 PF06698.9 MSTRG.93346.1_1 - 3.3 7.7 5.6 8.2 6.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Spc24 PF08286.9 MSTRG.93346.1_1 - 3.8 7.7 11.3 17 5.5 0.4 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Mnd1 PF03962.13 MSTRG.93346.1_1 - 4.4 7.0 12.0 12 5.6 1.5 2.0 1 1 1 2 2 2 0 Mnd1 family ZapB PF06005.10 MSTRG.93346.1_1 - 5.6 7.3 16.1 3.4 8.0 0.5 3.1 2 1 1 3 3 3 0 Cell division protein ZapB SURF6 PF04935.10 MSTRG.48931.1_2 - 0.03 13.9 0.0 0.034 13.7 0.0 1.0 1 0 0 1 1 1 0 Surfeit locus protein 6 V-ATPase_C PF03223.13 MSTRG.95602.1_3 - 1.4e-64 218.7 4.5 1.5e-64 218.6 4.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Folliculin PF11704.6 MSTRG.95602.1_3 - 0.072 12.8 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport HTH_38 PF13936.4 MSTRG.97812.1_2 - 1.1e-05 24.9 0.1 1.6e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.97812.1_2 - 0.00022 20.8 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Ribosomal_S13_N PF08069.10 MSTRG.97812.1_2 - 0.035 14.0 3.2 0.27 11.2 0.1 2.9 2 1 1 3 3 3 0 Ribosomal S13/S15 N-terminal domain Globin PF00042.20 MSTRG.91709.1_1 - 2.5e-18 66.5 0.0 3.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Globin HTH_Tnp_Tc3_2 PF01498.16 MSTRG.126557.1_3 - 9.5e-13 48.1 3.1 1.2e-12 47.8 3.1 1.1 1 0 0 1 1 1 1 Transposase SH3_9 PF14604.4 MSTRG.15296.1_2 - 0.001 18.7 0.1 0.0025 17.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 MSTRG.15296.1_2 - 0.043 13.4 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Variant SH3 domain ARID PF01388.19 MSTRG.19763.1_2 - 0.08 13.5 0.1 0.2 12.2 0.1 1.7 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain CysG_dimeriser PF10414.7 MSTRG.19763.1_3 - 0.015 14.8 0.5 0.015 14.8 0.5 1.8 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region Filament PF00038.19 MSTRG.106578.1_2 - 3.3e-26 92.5 6.9 4.3e-26 92.1 6.9 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.12 MSTRG.106578.1_2 - 1.4e-17 64.2 15.9 1.4e-17 64.2 15.9 1.6 2 0 0 2 2 2 1 Intermediate filament head (DNA binding) region Mis14 PF08641.10 MSTRG.106578.1_2 - 0.00029 21.0 2.0 0.00044 20.4 2.0 1.2 1 0 0 1 1 1 1 Kinetochore protein Mis14 like IncA PF04156.12 MSTRG.106578.1_2 - 0.0039 16.9 0.0 0.0056 16.4 0.0 1.1 1 0 0 1 1 1 1 IncA protein bZIP_1 PF00170.19 MSTRG.106578.1_2 - 0.048 13.6 3.7 2.4 8.2 0.8 2.6 2 1 0 2 2 2 0 bZIP transcription factor DUF972 PF06156.11 MSTRG.106578.1_2 - 0.41 11.2 4.5 6.8 7.2 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2157 PF09925.7 MSTRG.28704.1_2 - 0.024 14.3 0.2 0.026 14.2 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Collagen PF01391.16 MSTRG.41142.1_2 - 7.2e-62 204.9 288.9 7.9e-08 31.8 30.8 10.3 1 1 7 8 8 8 8 Collagen triple helix repeat (20 copies) C1q PF00386.19 MSTRG.41142.1_2 - 2.2e-34 118.3 0.4 3.7e-34 117.6 0.4 1.4 1 0 0 1 1 1 1 C1q domain CAP_N PF01213.17 MSTRG.29203.1_3 - 2e-20 73.4 2.4 2.2e-20 73.2 2.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.9 MSTRG.29203.1_3 - 2.1e-07 30.6 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal SH PF01445.15 MSTRG.25345.1_3 - 0.025 14.4 1.4 0.035 14.0 1.4 1.2 1 0 0 1 1 1 0 Viral small hydrophobic protein RVT_1 PF00078.25 MSTRG.126782.1_3 - 7.9e-15 54.8 0.0 8.7e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C2 PF00648.19 MSTRG.34953.1_3 - 5.5e-15 55.0 0.0 7.2e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Glyco_hydro_85 PF03644.11 MSTRG.24572.1_2 - 0.0044 16.4 0.0 0.0046 16.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 ANAPC4_WD40 PF12894.5 MSTRG.42825.1_1 - 0.00017 21.7 0.0 1.1 9.5 0.0 2.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.30 MSTRG.42825.1_1 - 0.00053 20.6 0.0 0.11 13.3 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat UCR_hinge PF02320.14 MSTRG.142388.1_2 - 1.1e-21 76.6 7.5 1.8e-21 76.0 7.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Hist_deacetyl PF00850.17 MSTRG.63633.1_1 - 1.3e-29 103.5 0.0 1.5e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain HTH_34 PF13601.4 MSTRG.63633.1_2 - 0.071 13.2 0.4 0.15 12.2 0.1 1.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain Tankyrase_bdg_C PF15327.4 MSTRG.70182.1_3 - 6.6e-35 120.9 7.0 8.1e-35 120.6 7.0 1.1 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain ubiquitin PF00240.21 MSTRG.83924.1_2 - 1.2e-06 28.0 0.0 1.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 MSTRG.83924.1_2 - 8.5e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.4 MSTRG.83924.1_2 - 0.0042 17.1 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.6 MSTRG.83924.1_2 - 0.029 14.5 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 TUG ubiquitin-like domain Arf PF00025.19 MSTRG.103484.1_1 - 2.3e-75 251.7 0.2 3.1e-75 251.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 MSTRG.103484.1_1 - 3.7e-13 49.2 0.0 5.5e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.11 MSTRG.103484.1_1 - 8.5e-13 48.5 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 MSTRG.103484.1_1 - 3.7e-11 42.7 0.0 5.2e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.18 MSTRG.103484.1_1 - 1.3e-10 40.9 0.8 1.8e-07 30.6 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.10 MSTRG.103484.1_1 - 8.7e-10 38.2 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 MSTRG.103484.1_1 - 0.0006 19.8 0.0 0.00091 19.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 MSTRG.103484.1_1 - 0.067 12.4 0.2 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Carn_acyltransf PF00755.18 MSTRG.100513.1_3 - 1.8e-76 257.9 0.0 2.3e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DNA_methylase PF00145.15 MSTRG.15306.1_2 - 3.4e-14 52.8 0.0 3.7e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase MTS PF05175.12 MSTRG.15306.1_2 - 0.0001 21.8 0.0 0.00012 21.5 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.13 MSTRG.15306.1_2 - 0.017 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.14 MSTRG.15306.1_2 - 0.078 12.6 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.10 MSTRG.15306.1_2 - 0.11 13.1 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.4 MSTRG.15306.1_2 - 0.11 13.1 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Rad60-SLD_2 PF13881.4 MSTRG.30499.3_1 - 0.011 15.8 0.6 0.02 14.9 0.6 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.21 MSTRG.30499.3_1 - 0.033 13.8 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF2407 PF10302.7 MSTRG.30499.3_1 - 0.053 14.0 0.6 0.097 13.1 0.6 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain mRNA_decap_C PF16741.3 MSTRG.30499.3_2 - 0.14 11.3 0.8 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus TPR_2 PF07719.15 MSTRG.30499.3_2 - 2.2 8.5 4.2 7.4 6.8 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TMA7 PF09072.8 MSTRG.95397.1_3 - 2e-25 89.3 22.4 2.8e-25 88.8 22.4 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 CALM_bind PF16025.3 MSTRG.127344.1_1 - 0.032 14.5 0.2 0.037 14.3 0.2 1.1 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding FXMRP1_C_core PF12235.6 MSTRG.127344.1_1 - 0.053 14.0 0.2 0.063 13.8 0.2 1.1 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF3915 PF13054.4 MSTRG.83217.1_1 - 0.16 11.8 4.4 0.28 11.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 MSTRG.83217.1_1 - 4.6 5.3 13.4 6.3 4.8 13.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family Auts2 PF15336.4 MSTRG.32673.1_2 - 0.24 11.4 8.4 0.28 11.2 8.4 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein SNARE PF05739.17 MSTRG.41250.1_3 - 8.3e-08 32.0 1.8 1.6e-07 31.1 1.8 1.5 1 0 0 1 1 1 1 SNARE domain Lysis_col PF02402.14 MSTRG.103081.1_2 - 0.027 14.2 0.3 6.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Lysis protein tRNA-synt_1c_C PF03950.16 MSTRG.134726.1_2 - 1.2e-16 61.0 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PCIF1_WW PF12237.6 MSTRG.28476.1_1 - 0.0012 18.4 1.2 0.0058 16.1 0.1 2.4 2 0 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain EF-hand_11 PF08976.9 MSTRG.28476.1_1 - 0.087 13.6 0.1 0.3 11.9 0.1 2.0 1 1 1 2 2 2 0 EF-hand domain Chalcone_2 PF16035.3 MSTRG.28476.1_1 - 0.11 12.2 1.5 0.17 11.5 0.4 1.8 1 1 1 2 2 2 0 Chalcone isomerase like DDE_3 PF13358.4 MSTRG.43460.1_3 - 1.8e-08 34.1 0.1 2.2e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2157 PF09925.7 MSTRG.4033.1_3 - 0.013 15.1 0.1 0.016 14.9 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) HMA PF00403.24 MSTRG.33156.1_2 - 2.6e-10 40.4 0.3 3.5e-10 40.0 0.3 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain STPPase_N PF16891.3 MSTRG.33156.1_2 - 0.019 15.3 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain CD52 PF15116.4 MSTRG.122084.1_2 - 0.11 12.4 0.5 0.17 11.8 0.5 1.3 1 0 0 1 1 1 0 CAMPATH-1 antigen HTH_Tnp_Tc3_2 PF01498.16 MSTRG.67753.1_1 - 0.032 14.4 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 Transposase SF3b10 PF07189.9 MSTRG.35093.1_1 - 5.9e-39 131.9 0.0 8.9e-39 131.3 0.0 1.3 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF2264 PF10022.7 MSTRG.35093.1_1 - 0.081 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Spectrin PF00435.19 MSTRG.57072.1_3 - 1.5e-06 28.5 32.3 1.3e-05 25.5 5.8 5.2 3 2 1 4 4 4 2 Spectrin repeat GM_CSF PF01109.15 MSTRG.57072.1_3 - 0.0064 16.5 0.6 3.3 7.8 0.0 2.6 2 0 0 2 2 2 2 Granulocyte-macrophage colony-stimulating factor Zot PF05707.10 MSTRG.57072.1_3 - 0.018 14.5 0.1 0.044 13.3 0.1 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ATP_sub_h PF10775.7 MSTRG.57072.1_3 - 0.026 14.4 0.3 0.72 9.8 0.0 2.8 2 0 0 2 2 2 0 ATP synthase complex subunit h Phage_GP20 PF06810.9 MSTRG.57072.1_3 - 0.55 9.9 12.9 3.6 7.2 0.2 4.1 3 2 1 5 5 5 0 Phage minor structural protein GP20 CorA PF01544.16 MSTRG.57072.1_3 - 1.7 7.7 18.6 0.027 13.7 2.6 3.5 1 1 2 4 4 4 0 CorA-like Mg2+ transporter protein FUSC PF04632.10 MSTRG.57072.1_3 - 4.5 5.6 18.2 0.88 7.9 5.5 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF4407 PF14362.4 MSTRG.57072.1_3 - 5.8 6.0 25.0 32 3.6 13.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) PIG-L PF02585.15 MSTRG.64747.3_1 - 0.0039 17.7 0.0 0.0048 17.4 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ArfGap PF01412.16 MSTRG.114551.1_2 - 1.4e-12 47.5 0.0 1.7e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf V-set PF07686.15 MSTRG.62448.1_2 - 1.4e-11 44.3 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 MSTRG.62448.1_2 - 0.0021 18.1 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain PRIMA1 PF16101.3 MSTRG.62448.1_2 - 0.029 14.3 0.5 0.036 14.0 0.5 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 C1-set_C PF16196.3 MSTRG.62448.1_2 - 0.035 13.4 0.4 0.052 12.8 0.4 1.3 1 0 0 1 1 1 0 C1-set C-terminal domain Interfer-bind PF09294.8 MSTRG.62448.1_2 - 0.036 14.3 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III CMAS PF02353.18 MSTRG.62448.1_2 - 0.068 12.3 0.0 0.08 12.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Syndecan PF01034.18 MSTRG.62448.1_2 - 0.18 11.6 0.4 0.46 10.3 0.4 1.7 2 0 0 2 2 2 0 Syndecan domain DUF2613 PF11021.6 MSTRG.62448.1_2 - 7.1 6.7 8.6 9.1 6.3 7.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) PT-HINT PF07591.9 MSTRG.29805.1_2 - 0.072 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Pretoxin HINT domain ARF7EP_C PF14949.4 MSTRG.19520.1_3 - 3.7 8.1 10.8 0.56 10.7 6.7 1.6 2 0 0 2 2 2 0 ARF7 effector protein C-terminus Myosin_head PF00063.19 MSTRG.71849.1_3 - 1.2e-35 122.8 0.3 1.4e-35 122.5 0.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.17 MSTRG.71849.1_3 - 2.9e-05 23.7 0.1 6.1e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Big_2 PF02368.16 MSTRG.71849.1_3 - 0.00029 20.5 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 2) DUF1866 PF08952.9 MSTRG.31069.1_3 - 0.041 13.6 0.1 0.057 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) CAF1 PF04857.18 MSTRG.19767.1_3 - 3.7e-23 82.1 0.2 2.6e-12 46.4 0.0 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease ENTH PF01417.18 MSTRG.141665.1_3 - 4.4e-08 33.1 0.0 5.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 ENTH domain RabGAP-TBC PF00566.16 MSTRG.122316.1_3 - 0.0043 16.6 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DDE_3 PF13358.4 MSTRG.5683.1_2 - 0.0082 15.8 0.1 0.0093 15.6 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2309 PF10070.7 MSTRG.5683.1_2 - 0.084 11.0 0.0 0.095 10.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) zf-C2H2 PF00096.24 MSTRG.16500.1_2 - 2.7e-09 36.8 6.6 2.2e-05 24.5 1.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.16500.1_2 - 5.2e-06 26.7 3.6 0.017 15.8 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.4 MSTRG.16500.1_2 - 1.3e-05 25.3 16.5 0.016 15.5 1.3 3.9 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2_11 PF16622.3 MSTRG.16500.1_2 - 0.0011 18.6 2.5 0.0061 16.2 0.1 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-met PF12874.5 MSTRG.16500.1_2 - 0.0011 19.1 2.8 0.29 11.4 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-LYAR PF08790.9 MSTRG.16500.1_2 - 0.016 14.9 3.7 0.8 9.5 0.4 2.6 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.8 MSTRG.16500.1_2 - 0.019 14.9 0.5 0.55 10.3 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.4 MSTRG.16500.1_2 - 0.044 13.6 7.8 0.073 12.9 1.0 2.6 2 1 1 3 3 3 0 C2H2-type zinc finger XPA_N PF01286.16 MSTRG.16500.1_2 - 0.071 13.0 1.0 3.5 7.6 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal DUSP PF06337.10 MSTRG.1545.2_3 - 1.6e-22 79.8 0.3 2.3e-22 79.3 0.3 1.2 1 0 0 1 1 1 1 DUSP domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.103452.1_3 - 6.7e-08 32.5 0.7 9.8e-08 32.0 0.7 1.2 1 0 0 1 1 1 1 Transposase YqhR PF11085.6 MSTRG.32596.1_2 - 0.087 12.6 3.7 0.11 12.3 3.7 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR Mito_carr PF00153.25 MSTRG.49441.2_1 - 5.7e-17 61.3 0.0 6.5e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein DUF3459 PF11941.6 MSTRG.22009.1_2 - 0.012 15.7 2.0 0.017 15.3 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Hist_deacetyl PF00850.17 MSTRG.82068.1_2 - 2.2e-28 99.5 0.0 2.6e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Kinesin PF00225.21 MSTRG.140088.1_1 - 1.2e-33 116.4 0.0 1.2e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.3 MSTRG.140088.1_1 - 4.9e-20 71.9 0.0 5.8e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.12 MSTRG.140088.1_1 - 0.0014 17.7 0.2 0.0027 16.8 0.2 1.5 1 1 1 2 2 2 1 PIF1-like helicase AAA_30 PF13604.4 MSTRG.140088.1_1 - 0.0052 16.4 0.0 0.0058 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.4 MSTRG.140088.1_1 - 0.07 13.3 0.2 0.072 13.2 0.1 1.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.14 MSTRG.140088.1_1 - 0.15 11.4 0.5 0.13 11.5 0.5 1.3 1 1 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.4 MSTRG.140088.1_1 - 0.16 12.2 0.0 0.51 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain C1q PF00386.19 MSTRG.69620.6_1 - 2.6e-23 82.5 0.4 3.4e-23 82.1 0.4 1.2 1 0 0 1 1 1 1 C1q domain TMIE PF16038.3 MSTRG.69620.6_1 - 0.087 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 TMIE protein WD40 PF00400.30 MSTRG.81635.1_3 - 1.3e-36 123.8 13.4 4e-10 40.0 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.81635.1_3 - 1.7e-22 79.3 1.7 1.9e-08 34.3 0.1 4.0 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 MSTRG.81635.1_3 - 2.8e-08 33.7 0.6 0.00045 20.0 0.1 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.12 MSTRG.81635.1_3 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40_like PF17005.3 MSTRG.81635.1_3 - 0.0066 15.7 0.0 0.055 12.7 0.0 2.4 3 1 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.3 MSTRG.81635.1_3 - 0.01 14.7 1.9 0.32 9.8 0.0 2.1 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.10 MSTRG.81635.1_3 - 0.053 11.4 0.5 4.1 5.1 0.1 2.5 2 1 1 3 3 3 0 IKI3 family Toxin_31 PF08119.9 MSTRG.81635.1_3 - 0.24 11.0 1.6 2.2 7.9 0.3 2.4 2 0 0 2 2 2 0 Scorpion acidic alpha-KTx toxin family Eapp_C PF10238.7 MSTRG.60913.1_1 - 0.0038 17.2 3.7 0.0045 16.9 3.7 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein Plasmodium_Vir PF05795.9 MSTRG.60913.1_1 - 0.0084 15.4 9.6 0.01 15.2 9.6 1.0 1 0 0 1 1 1 1 Plasmodium vivax Vir protein CobT PF06213.10 MSTRG.60913.1_1 - 0.023 14.0 16.6 0.029 13.6 16.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.3 MSTRG.60913.1_1 - 0.04 13.2 11.8 0.046 13.0 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Draxin PF15550.4 MSTRG.60913.1_1 - 0.04 13.6 11.3 0.045 13.5 11.3 1.1 1 0 0 1 1 1 0 Draxin NARP1 PF12569.6 MSTRG.60913.1_1 - 0.045 12.5 15.2 0.052 12.3 15.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_Ag35 PF03286.12 MSTRG.60913.1_1 - 0.072 12.7 17.0 0.099 12.3 17.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC27 PF09507.8 MSTRG.60913.1_1 - 0.11 11.7 21.1 0.12 11.6 21.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1510 PF07423.9 MSTRG.60913.1_1 - 0.14 11.4 17.6 0.17 11.2 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SPT16 PF08644.9 MSTRG.60913.1_1 - 0.17 11.9 4.7 0.22 11.6 4.7 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4820 PF16091.3 MSTRG.60913.1_1 - 0.23 10.6 11.3 0.31 10.2 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3807 PF12720.5 MSTRG.60913.1_1 - 0.29 11.3 15.3 0.38 10.9 15.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) FLO_LFY PF01698.14 MSTRG.60913.1_1 - 0.51 9.3 8.8 0.63 9.1 8.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Vfa1 PF08432.8 MSTRG.60913.1_1 - 0.54 10.4 19.0 0.63 10.2 19.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.15 MSTRG.60913.1_1 - 0.67 8.5 9.2 0.73 8.4 9.2 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_3_Rpc31 PF11705.6 MSTRG.60913.1_1 - 0.68 10.0 22.7 0.94 9.5 22.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF913 PF06025.10 MSTRG.60913.1_1 - 0.74 8.6 8.5 0.91 8.3 8.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.15 MSTRG.60913.1_1 - 0.87 9.5 7.7 0.98 9.4 7.7 1.1 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.8 MSTRG.60913.1_1 - 0.93 8.8 15.3 1.3 8.4 15.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) FemAB PF02388.14 MSTRG.60913.1_1 - 1.8 7.3 10.4 2.2 6.9 10.4 1.3 1 0 0 1 1 1 0 FemAB family CDC45 PF02724.12 MSTRG.60913.1_1 - 1.8 6.6 11.8 1.9 6.6 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.11 MSTRG.60913.1_1 - 1.9 7.1 10.5 2.1 6.9 10.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.10 MSTRG.60913.1_1 - 2.5 7.7 16.1 3.4 7.3 16.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3340 PF11818.6 MSTRG.60913.1_1 - 2.6 8.1 23.2 3.7 7.6 23.2 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Mucin PF01456.15 MSTRG.60913.1_1 - 2.6 7.9 10.3 3 7.7 10.3 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Zip PF02535.20 MSTRG.60913.1_1 - 3.5 6.6 5.1 3.7 6.5 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.14 MSTRG.60913.1_1 - 4.3 7.2 5.5 4.8 7.0 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.6 MSTRG.60913.1_1 - 5.6 5.5 8.4 5.9 5.5 8.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.7 MSTRG.60913.1_1 - 5.8 5.7 6.0 6.1 5.6 6.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein APG6 PF04111.10 MSTRG.60913.1_1 - 6.2 6.0 24.0 8.6 5.5 24.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Paramyxo_ncap PF00973.17 MSTRG.60913.1_1 - 7.1 5.3 9.7 7.2 5.3 9.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Sec62 PF03839.14 MSTRG.60913.1_1 - 8 5.8 12.7 11 5.4 12.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Cellulose_synt PF03552.12 MSTRG.60913.1_1 - 9.5 4.4 6.5 10 4.3 6.5 1.1 1 0 0 1 1 1 0 Cellulose synthase PIEZO PF15917.3 MSTRG.40294.1_1 - 0.1 11.9 1.1 0.14 11.5 1.1 1.1 1 0 0 1 1 1 0 Piezo C1q PF00386.19 MSTRG.8884.1_2 - 5.3e-24 84.7 0.1 7.7e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 C1q domain PA14 PF07691.10 MSTRG.8884.1_2 - 0.028 14.0 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 PA14 domain zf-HIT PF04438.14 MSTRG.144382.1_1 - 0.39 10.5 7.1 12 5.7 0.2 3.3 3 0 0 3 3 3 0 HIT zinc finger VWD PF00094.23 MSTRG.144382.1_1 - 2.3 8.3 5.9 18 5.4 0.5 2.7 2 1 1 3 3 3 0 von Willebrand factor type D domain zf-RRN7 PF11781.6 MSTRG.144382.1_1 - 2.7 7.6 13.1 1.7 8.3 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.5 MSTRG.144382.1_2 - 4.3 7.3 8.8 1.7e+02 2.2 8.8 2.6 1 1 0 1 1 1 0 Double zinc ribbon Trypsin PF00089.24 MSTRG.89899.1_2 - 2.7e-14 53.4 0.2 3.2e-14 53.1 0.2 1.1 1 0 0 1 1 1 1 Trypsin SNF PF00209.16 MSTRG.32258.1_2 - 7.3e-06 24.8 0.9 7.4e-06 24.8 0.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RVT_1 PF00078.25 MSTRG.4439.1_3 - 0.00099 18.5 0.1 0.0011 18.4 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.21 MSTRG.4568.1_1 - 0.002 18.2 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DHFR_1 PF00186.17 MSTRG.115736.1_3 - 1.1e-24 86.8 0.0 1.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase Adaptin_N PF01602.18 MSTRG.15170.1_1 - 1.3e-06 27.2 0.0 1.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.18 MSTRG.15170.1_1 - 1.7e-06 28.1 0.1 3.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain BORG_CEP PF14957.4 MSTRG.95226.1_2 - 1e-07 33.0 0.3 1.8e-07 32.2 0.3 1.4 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.26 MSTRG.95226.1_2 - 0.00046 20.4 0.1 0.0009 19.5 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Ras PF00071.20 MSTRG.36237.1_1 - 1e-48 164.9 0.0 1.8e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.11 MSTRG.36237.1_1 - 7e-27 93.9 0.0 1.3e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 MSTRG.36237.1_1 - 1e-11 44.5 0.0 1.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 MSTRG.36237.1_1 - 6.8e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 MSTRG.36237.1_1 - 0.00011 22.1 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 MSTRG.36237.1_1 - 0.008 15.6 0.1 0.025 14.0 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.4 MSTRG.36237.1_1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.14 MSTRG.36237.1_1 - 0.047 13.5 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.4 MSTRG.36237.1_1 - 0.093 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain FG-GAP PF01839.21 MSTRG.34302.1_2 - 7.8e-20 70.5 25.9 6.7e-12 45.2 5.5 4.0 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.4 MSTRG.34302.1_2 - 3.3e-16 59.5 11.4 9.9e-11 41.9 1.7 3.8 1 1 3 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RVT_1 PF00078.25 MSTRG.140134.1_1 - 1.5e-08 34.3 0.1 1.6e-08 34.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RmlD_sub_bind PF04321.15 MSTRG.21035.1_2 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain zf-H2C2_2 PF13465.4 MSTRG.1217.1_2 - 0.0062 16.8 2.1 0.012 16.0 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger double domain zf-met PF12874.5 MSTRG.1217.1_2 - 0.17 12.2 1.4 0.17 12.2 1.4 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.4 MSTRG.1217.1_2 - 0.38 11.6 3.3 1 10.3 3.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger BLOC1_2 PF10046.7 MSTRG.25584.1_2 - 0.029 14.5 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cep57_MT_bd PF06657.11 MSTRG.25584.1_2 - 0.044 14.1 0.2 0.89 9.9 0.1 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMF_DNA_bd PF12329.6 MSTRG.25584.1_2 - 0.071 13.0 0.8 2 8.4 0.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Glyco_transf_22 PF03901.15 MSTRG.30868.2_3 - 2.7e-13 49.8 3.5 3.4e-13 49.5 3.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family RRM_1 PF00076.20 MSTRG.97830.1_1 - 3.3e-17 61.9 0.0 8.9e-15 54.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 MSTRG.97830.1_1 - 1e-05 25.4 0.0 0.0019 18.1 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif Spo7_2_N PF15407.4 MSTRG.97830.1_1 - 0.0061 16.1 0.0 3.7 7.2 0.0 2.3 2 0 0 2 2 2 2 Sporulation protein family 7 HSP70 PF00012.18 MSTRG.88832.2_1 - 3.9e-49 167.2 1.7 4.6e-49 167.0 1.7 1.0 1 0 0 1 1 1 1 Hsp70 protein SHS2_FTSA PF02491.18 MSTRG.88832.2_1 - 0.059 13.7 1.4 0.68 10.2 0.3 2.3 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA DUF2798 PF11391.6 MSTRG.44372.1_3 - 0.16 11.9 3.7 8.7 6.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) DAGK_acc PF00609.17 MSTRG.52913.1_2 - 9e-55 185.2 0.0 1.8e-54 184.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.4 MSTRG.52913.1_2 - 3.2e-47 160.7 3.0 9.9e-40 136.4 0.4 2.3 1 1 1 2 2 2 2 Diacylglycerol kinase N-terminus DAGK_cat PF00781.22 MSTRG.52913.1_2 - 7.2e-28 96.6 0.0 1.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.20 MSTRG.52913.1_2 - 2e-19 69.1 32.9 5.5e-12 45.3 8.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.30 MSTRG.52913.1_2 - 7.4e-09 34.4 2.2 0.00081 18.6 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.4 MSTRG.52913.1_2 - 3.5e-06 26.4 0.8 0.00022 20.8 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.4 MSTRG.52913.1_2 - 9.3e-06 25.9 3.2 1.2e-05 25.5 0.3 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.4 MSTRG.52913.1_2 - 0.00026 20.3 2.8 1.3 8.5 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.4 MSTRG.52913.1_2 - 0.098 12.3 2.1 21 4.8 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain pair HOK_GEF PF01848.14 MSTRG.44968.1_1 - 0.098 11.9 1.4 10 5.5 0.1 2.3 2 0 0 2 2 2 0 Hok/gef family UCH PF00443.27 MSTRG.89746.1_2 - 3.3e-09 36.5 0.4 4.3e-09 36.1 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SWIRM PF04433.15 MSTRG.96366.1_1 - 2.1e-10 40.7 0.0 2.3e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 SWIRM domain RPA_C PF08784.9 MSTRG.96366.1_1 - 0.009 16.5 0.0 0.011 16.2 0.0 1.1 1 0 0 1 1 1 1 Replication protein A C terminal LisH PF08513.9 MSTRG.96366.1_1 - 0.041 13.8 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 LisH Coatomer_WDAD PF04053.12 MSTRG.96366.1_1 - 0.051 12.5 0.0 0.054 12.4 0.0 1.0 1 0 0 1 1 1 0 Coatomer WD associated region Glyco_transf_29 PF00777.16 MSTRG.85259.1_2 - 6.7e-29 100.9 0.0 7e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) RVT_1 PF00078.25 MSTRG.8340.1_1 - 1.3e-11 44.3 0.1 1.5e-11 44.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Calpain_inhib PF00748.17 MSTRG.93195.6_1 - 6.1e-21 75.1 6.1 3.5e-20 72.7 1.5 2.0 2 0 0 2 2 2 2 Calpain inhibitor AbfB PF05270.11 MSTRG.13032.1_3 - 0.13 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) domain NolX PF05819.9 MSTRG.1865.1_3 - 0.026 12.6 0.0 0.028 12.5 0.0 1.0 1 0 0 1 1 1 0 NolX protein ADK PF00406.20 MSTRG.137741.1_2 - 8.3e-50 168.7 0.1 1.1e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.4 MSTRG.137741.1_2 - 1.9e-36 125.4 0.4 2.6e-36 124.9 0.4 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 MSTRG.137741.1_2 - 2.7e-08 34.0 0.0 1.6e-07 31.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.4 MSTRG.137741.1_2 - 8.7e-06 26.1 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.15 MSTRG.137741.1_2 - 0.00022 20.8 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Cytidylate_kin PF02224.16 MSTRG.137741.1_2 - 0.0051 16.4 0.1 0.24 10.9 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase AAA_22 PF13401.4 MSTRG.137741.1_2 - 0.038 14.1 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.4 MSTRG.137741.1_2 - 0.083 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.10 MSTRG.137741.1_2 - 0.096 11.8 0.1 0.21 10.8 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin dNK PF01712.17 MSTRG.137741.1_2 - 0.18 11.5 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase DDE_3 PF13358.4 MSTRG.5483.1_1 - 4.8e-08 32.7 0.5 5.1e-08 32.7 0.5 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_92 PF01697.25 MSTRG.5483.1_1 - 0.014 14.9 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 92 PXA PF02194.13 MSTRG.85555.1_3 - 1.9e-15 57.0 0.0 3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 PXA domain Myosin_tail_1 PF01576.17 MSTRG.125997.1_2 - 7.1e-47 159.8 25.2 7.8e-47 159.6 25.2 1.0 1 0 0 1 1 1 1 Myosin tail ADIP PF11559.6 MSTRG.125997.1_2 - 0.00024 21.1 16.2 0.00024 21.1 16.2 1.2 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4472 PF14739.4 MSTRG.125997.1_2 - 0.0017 18.9 13.4 0.0017 18.9 13.4 1.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4472) DUF4515 PF14988.4 MSTRG.125997.1_2 - 0.012 15.4 16.7 0.031 14.0 8.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) HIP1_clath_bdg PF16515.3 MSTRG.125997.1_2 - 0.02 15.3 16.2 0.025 15.0 16.2 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6 PF04111.10 MSTRG.125997.1_2 - 0.038 13.3 18.8 0.044 13.0 18.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.12 MSTRG.125997.1_2 - 0.047 13.4 11.7 0.015 15.0 9.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.20 MSTRG.125997.1_2 - 0.047 13.8 12.6 0.069 13.3 12.6 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.10 MSTRG.125997.1_2 - 0.047 13.6 5.0 0.06 13.2 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.9 MSTRG.125997.1_2 - 0.056 13.4 14.3 0.25 11.4 4.0 2.6 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF342 PF03961.11 MSTRG.125997.1_2 - 0.092 11.2 7.6 0.11 11.0 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMPIT PF07851.11 MSTRG.125997.1_2 - 0.11 11.6 5.7 0.13 11.3 5.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein ERM PF00769.17 MSTRG.125997.1_2 - 0.16 11.7 26.9 0.23 11.1 26.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FlaC_arch PF05377.9 MSTRG.125997.1_2 - 0.16 12.3 9.3 1.1 9.6 1.3 3.1 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) JIP_LZII PF16471.3 MSTRG.125997.1_2 - 0.18 11.9 10.9 0.32 11.1 10.3 1.8 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Reo_sigmaC PF04582.10 MSTRG.125997.1_2 - 0.18 11.1 1.2 0.21 10.8 1.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.9 MSTRG.125997.1_2 - 0.19 10.5 12.9 0.23 10.2 12.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.9 MSTRG.125997.1_2 - 0.19 11.9 16.3 0.052 13.7 6.2 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SHE3 PF17078.3 MSTRG.125997.1_2 - 0.21 11.2 12.6 0.55 9.8 1.7 2.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 THOC7 PF05615.11 MSTRG.125997.1_2 - 0.23 11.6 16.4 0.38 10.9 16.2 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 GAS PF13851.4 MSTRG.125997.1_2 - 0.25 10.6 16.8 0.42 9.8 16.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.6 MSTRG.125997.1_2 - 0.27 10.4 15.9 0.36 10.0 15.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.9 MSTRG.125997.1_2 - 0.29 11.6 11.6 5.9 7.4 11.6 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Golgin_A5 PF09787.7 MSTRG.125997.1_2 - 0.29 10.4 20.0 0.32 10.3 20.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Prominin PF05478.9 MSTRG.125997.1_2 - 0.38 8.5 4.7 0.47 8.2 4.7 1.1 1 0 0 1 1 1 0 Prominin COG2 PF06148.9 MSTRG.125997.1_2 - 0.47 10.4 7.2 1.1 9.3 7.1 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TSC22 PF01166.16 MSTRG.125997.1_2 - 0.47 10.7 12.6 1.2 9.4 3.0 2.8 1 1 2 3 3 3 0 TSC-22/dip/bun family TBPIP PF07106.11 MSTRG.125997.1_2 - 0.61 9.7 9.1 0.84 9.3 8.5 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CALCOCO1 PF07888.9 MSTRG.125997.1_2 - 0.62 8.4 20.0 0.64 8.4 20.0 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.12 MSTRG.125997.1_2 - 0.69 9.5 23.2 0.75 9.4 23.2 1.1 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.5 MSTRG.125997.1_2 - 0.71 9.9 21.8 2.3 8.2 21.8 1.8 1 1 0 1 1 1 0 Tropomyosin like FPP PF05911.9 MSTRG.125997.1_2 - 0.74 7.9 16.3 0.85 7.7 16.3 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Uso1_p115_C PF04871.11 MSTRG.125997.1_2 - 0.75 10.0 19.1 1 9.6 6.6 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nup54 PF13874.4 MSTRG.125997.1_2 - 0.83 9.6 14.7 0.39 10.7 2.3 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF972 PF06156.11 MSTRG.125997.1_2 - 0.86 10.1 12.5 1.7 9.2 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PEARLI-4 PF05278.10 MSTRG.125997.1_2 - 0.99 8.8 12.1 0.79 9.1 3.2 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4695 PF15766.3 MSTRG.125997.1_2 - 1 9.5 11.5 1.5 8.9 9.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4695) Prefoldin PF02996.15 MSTRG.125997.1_2 - 1.1 9.1 10.3 0.71 9.7 1.2 2.4 1 1 1 2 2 2 0 Prefoldin subunit Phage_GPO PF05929.9 MSTRG.125997.1_2 - 1.4 8.4 9.6 1.7 8.1 9.6 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Rootletin PF15035.4 MSTRG.125997.1_2 - 1.4 8.8 20.5 1.9 8.4 20.5 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion OmpH PF03938.12 MSTRG.125997.1_2 - 1.9 8.4 18.2 0.75 9.7 14.1 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Cauli_AT PF03233.11 MSTRG.125997.1_2 - 1.9 8.2 5.0 1.1 9.0 2.1 1.8 1 1 1 2 2 2 0 Aphid transmission protein CcmH PF03918.12 MSTRG.125997.1_2 - 2.4 7.3 7.0 0.7 9.0 3.9 1.6 1 1 0 1 1 1 0 Cytochrome C biogenesis protein TPR_MLP1_2 PF07926.10 MSTRG.125997.1_2 - 2.8 7.9 23.6 0.53 10.2 9.9 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.10 MSTRG.125997.1_2 - 3.2 8.1 20.1 1.2 9.4 4.6 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) 5_nucleotid PF05761.12 MSTRG.125997.1_2 - 3.9 6.1 5.9 4.6 5.9 5.9 1.3 1 0 0 1 1 1 0 5' nucleotidase family V_ATPase_I PF01496.17 MSTRG.125997.1_2 - 6.8 4.3 9.2 7.1 4.3 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.6 MSTRG.125997.1_2 - 8.1 6.0 20.3 0.4 10.2 12.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF3552 PF12072.6 MSTRG.125997.1_2 - 8.4 5.6 22.0 11 5.3 22.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Adenylsucc_synt PF00709.19 MSTRG.33290.1_1 - 6.1e-68 229.5 0.1 7.2e-68 229.3 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Spectrin PF00435.19 MSTRG.33929.1_1 - 8.9e-147 479.2 99.6 1.6e-20 73.4 0.5 10.1 10 0 0 10 10 10 10 Spectrin repeat PH_9 PF15410.4 MSTRG.33929.1_1 - 1.8e-20 73.3 0.0 8.2e-20 71.2 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.27 MSTRG.33929.1_1 - 1.3e-16 60.8 0.0 4.4e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 MSTRG.33929.1_1 - 0.0052 17.0 0.2 0.033 14.5 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain HSBP1 PF06825.10 MSTRG.33929.1_1 - 0.11 12.3 3.2 60 3.5 0.0 4.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF1319 PF07028.9 MSTRG.33929.1_1 - 4.1 7.5 17.7 0.52 10.4 1.0 5.2 5 1 1 6 6 6 0 Protein of unknown function (DUF1319) RVT_1 PF00078.25 MSTRG.129245.1_3 - 0.00027 20.4 0.0 0.00028 20.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4274 PF14096.4 MSTRG.108365.1_3 - 0.082 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) FUN14 PF04930.13 MSTRG.14056.1_3 - 1e-23 83.4 0.8 1.4e-23 82.9 0.8 1.1 1 0 0 1 1 1 1 FUN14 family PMP22_Claudin PF00822.18 MSTRG.57735.1_2 - 2.6e-13 50.1 13.4 4.3e-13 49.3 13.4 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 MSTRG.57735.1_2 - 0.0073 15.9 16.8 0.0073 15.9 16.8 2.1 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction CoA_transf_3 PF02515.15 MSTRG.40249.1_2 - 2.1e-44 152.0 0.5 2.3e-44 151.9 0.5 1.0 1 0 0 1 1 1 1 CoA-transferase family III ANTH PF07651.14 MSTRG.32951.1_2 - 6.7e-12 44.8 1.7 7.8e-12 44.6 1.7 1.0 1 0 0 1 1 1 1 ANTH domain PXA PF02194.13 MSTRG.141058.1_1 - 4.5e-35 120.8 0.1 1e-34 119.7 0.1 1.6 1 0 0 1 1 1 1 PXA domain RGS PF00615.17 MSTRG.141058.1_1 - 1.7e-09 37.9 0.6 3.2e-09 37.0 0.6 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain zf-C3HC4_3 PF13920.4 MSTRG.116338.1_3 - 2.4 7.9 6.8 1.1 9.0 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TH1 PF04858.11 MSTRG.53267.1_3 - 0.022 13.3 0.0 0.026 13.1 0.0 1.0 1 0 0 1 1 1 0 TH1 protein Myosin_tail_1 PF01576.17 MSTRG.117382.1_2 - 1.7e-51 175.1 25.6 1.8e-51 175.0 25.6 1.0 1 0 0 1 1 1 1 Myosin tail HMMR_N PF15905.3 MSTRG.117382.1_2 - 0.00032 20.1 18.1 0.00038 19.9 18.1 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Uds1 PF15456.4 MSTRG.117382.1_2 - 0.00052 20.1 16.7 0.00062 19.8 16.3 1.2 1 1 0 1 1 1 1 Up-regulated During Septation MscS_porin PF12795.5 MSTRG.117382.1_2 - 0.00068 19.1 16.8 0.012 15.0 16.8 2.0 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain Topoisom_I PF01028.18 MSTRG.117382.1_2 - 0.0029 16.7 5.7 0.0037 16.4 5.7 1.2 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Filament PF00038.19 MSTRG.117382.1_2 - 0.0084 15.6 19.5 0.033 13.6 19.5 1.7 1 1 0 1 1 1 1 Intermediate filament protein Baculo_PEP_C PF04513.10 MSTRG.117382.1_2 - 0.016 15.1 1.3 0.12 12.3 0.2 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.9 MSTRG.117382.1_2 - 0.02 14.8 21.6 0.068 13.1 21.5 1.9 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF3584 PF12128.6 MSTRG.117382.1_2 - 0.021 12.2 17.3 0.022 12.2 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.8 MSTRG.117382.1_2 - 0.027 14.5 10.0 0.071 13.2 8.7 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.4 MSTRG.117382.1_2 - 0.031 13.5 14.6 0.034 13.4 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.12 MSTRG.117382.1_2 - 0.058 13.1 19.4 0.06 13.0 7.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF812 PF05667.9 MSTRG.117382.1_2 - 0.06 12.1 19.1 0.15 10.8 19.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Rootletin PF15035.4 MSTRG.117382.1_2 - 0.098 12.6 16.5 0.14 12.0 16.5 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Laminin_II PF06009.10 MSTRG.117382.1_2 - 0.11 12.4 10.9 0.076 12.9 8.7 1.7 1 1 1 2 2 2 0 Laminin Domain II LPP PF04728.11 MSTRG.117382.1_2 - 0.12 12.6 14.1 0.058 13.6 5.2 2.9 1 1 2 3 3 3 0 Lipoprotein leucine-zipper Golgin_A5 PF09787.7 MSTRG.117382.1_2 - 0.15 11.4 18.0 0.5 9.6 16.5 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 WXG100 PF06013.10 MSTRG.117382.1_2 - 0.17 12.0 8.6 2.5 8.3 6.7 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Mei5_like PF17021.3 MSTRG.117382.1_2 - 0.18 11.7 6.3 0.33 10.9 6.2 1.6 1 1 0 1 1 1 0 Putative double-strand recombination repair-like Phage_GPO PF05929.9 MSTRG.117382.1_2 - 0.18 11.3 10.3 0.24 10.9 10.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase LXG PF04740.10 MSTRG.117382.1_2 - 0.19 11.3 8.7 0.53 9.8 8.7 1.7 1 1 0 1 1 1 0 LXG domain of WXG superfamily ABC_tran_CTD PF16326.3 MSTRG.117382.1_2 - 0.21 11.8 21.9 3.9 7.7 8.8 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.5 MSTRG.117382.1_2 - 0.23 11.5 21.8 3.9 7.4 9.7 2.1 1 1 1 2 2 2 0 Tropomyosin like ALMT PF11744.6 MSTRG.117382.1_2 - 0.23 10.1 5.4 0.27 9.9 5.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter TMPIT PF07851.11 MSTRG.117382.1_2 - 0.25 10.4 10.9 0.32 10.0 10.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein Uso1_p115_C PF04871.11 MSTRG.117382.1_2 - 0.25 11.6 23.3 4.8 7.4 10.2 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.10 MSTRG.117382.1_2 - 0.26 11.2 23.5 0.2 11.6 21.1 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.4 MSTRG.117382.1_2 - 0.33 10.8 16.6 0.17 11.7 4.6 2.3 1 1 1 2 2 2 0 FlxA-like protein DUF1664 PF07889.10 MSTRG.117382.1_2 - 0.33 10.8 8.6 0.5 10.2 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.4 MSTRG.117382.1_2 - 0.41 10.9 25.3 2.1 8.6 25.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Mnd1 PF03962.13 MSTRG.117382.1_2 - 0.42 10.3 20.7 0.75 9.5 20.7 1.5 1 1 0 1 1 1 0 Mnd1 family Cnn_1N PF07989.9 MSTRG.117382.1_2 - 0.42 10.6 20.0 0.18 11.8 6.6 2.7 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Phage_GP20 PF06810.9 MSTRG.117382.1_2 - 0.44 10.2 15.1 3.1 7.5 4.6 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Sin3_corepress PF08295.10 MSTRG.117382.1_2 - 0.46 10.5 7.8 0.59 10.1 6.7 1.6 1 1 1 2 2 2 0 Sin3 family co-repressor YlqD PF11068.6 MSTRG.117382.1_2 - 0.47 10.7 17.0 0.88 9.8 15.8 1.8 1 1 0 1 1 1 0 YlqD protein HR1 PF02185.14 MSTRG.117382.1_2 - 0.5 10.4 21.3 0.27 11.2 17.7 2.3 2 1 0 2 2 2 0 Hr1 repeat DUF4140 PF13600.4 MSTRG.117382.1_2 - 0.57 10.5 19.5 1.4 9.3 6.4 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.11 MSTRG.117382.1_2 - 0.63 8.4 12.3 0.69 8.3 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_13 PF13166.4 MSTRG.117382.1_2 - 0.73 8.3 13.1 0.93 7.9 13.1 1.1 1 0 0 1 1 1 0 AAA domain FadA PF09403.8 MSTRG.117382.1_2 - 0.91 9.9 13.9 1.9 8.9 13.9 1.6 1 1 0 1 1 1 0 Adhesion protein FadA Exonuc_VII_L PF02601.13 MSTRG.117382.1_2 - 0.99 8.8 14.7 1 8.7 14.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bestrophin PF01062.19 MSTRG.117382.1_2 - 0.99 8.6 4.4 1.2 8.3 4.4 1.0 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel EMP24_GP25L PF01105.22 MSTRG.117382.1_2 - 1 9.2 9.1 1.9 8.3 3.8 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD GAS PF13851.4 MSTRG.117382.1_2 - 1 8.6 21.2 2.3 7.4 7.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.6 MSTRG.117382.1_2 - 1 9.3 21.5 1.2 9.1 8.9 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Snf7 PF03357.19 MSTRG.117382.1_2 - 1 8.8 18.1 0.74 9.2 17.1 1.3 1 1 0 1 1 1 0 Snf7 Spc7 PF08317.9 MSTRG.117382.1_2 - 1.1 7.9 20.4 1.3 7.7 20.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TRPM_tetra PF16519.3 MSTRG.117382.1_2 - 1.4 8.9 11.1 4.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Tetramerisation domain of TRPM CorA PF01544.16 MSTRG.117382.1_2 - 1.5 8.0 7.5 5.1 6.2 7.5 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SlyX PF04102.10 MSTRG.117382.1_2 - 1.7 9.2 20.7 9.2 6.8 6.0 3.0 1 1 2 3 3 3 0 SlyX APG6 PF04111.10 MSTRG.117382.1_2 - 1.7 7.8 20.5 0.37 10.0 11.1 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 Jnk-SapK_ap_N PF09744.7 MSTRG.117382.1_2 - 1.8 8.6 22.1 1.5 8.9 20.2 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 IncA PF04156.12 MSTRG.117382.1_2 - 1.9 8.1 21.3 3.4 7.3 21.3 1.5 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.7 MSTRG.117382.1_2 - 1.9 7.4 18.1 2.1 7.2 18.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.17 MSTRG.117382.1_2 - 2.5 5.8 9.3 2.7 5.6 9.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Alanine_zipper PF11839.6 MSTRG.117382.1_2 - 2.8 8.1 14.0 1.6 8.9 7.5 2.3 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein betaPIX_CC PF16523.3 MSTRG.117382.1_2 - 3.8 7.3 15.8 0.31 10.7 4.7 2.4 2 1 0 2 2 2 0 betaPIX coiled coil HemX PF04375.12 MSTRG.117382.1_2 - 4.1 6.5 16.2 40 3.2 16.2 1.9 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase THOC7 PF05615.11 MSTRG.117382.1_2 - 4.8 7.4 22.2 6.3e+02 0.5 22.2 2.3 1 1 0 1 1 1 0 Tho complex subunit 7 FlaC_arch PF05377.9 MSTRG.117382.1_2 - 4.9 7.5 11.4 18 5.6 1.4 3.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Med21 PF11221.6 MSTRG.117382.1_2 - 5.9 7.0 19.8 0.17 12.0 5.5 2.4 3 0 0 3 3 2 0 Subunit 21 of Mediator complex LMBR1 PF04791.14 MSTRG.117382.1_2 - 6.6 5.4 8.7 6.6 5.4 8.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein XhlA PF10779.7 MSTRG.117382.1_2 - 7.2 6.8 12.1 7.7 6.7 5.5 2.8 1 1 1 2 2 2 0 Haemolysin XhlA DUF972 PF06156.11 MSTRG.117382.1_2 - 7.4 7.1 14.5 11 6.6 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FUSC PF04632.10 MSTRG.117382.1_2 - 7.6 4.8 7.0 8.2 4.7 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Swi5 PF07061.9 MSTRG.117382.1_2 - 7.7 6.5 15.7 10 6.2 1.4 2.8 2 1 0 2 2 2 0 Swi5 CENP-H PF05837.10 MSTRG.117382.1_2 - 8.1 6.8 19.0 5.7 7.2 16.3 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF16 PF01519.14 MSTRG.117382.1_2 - 8.9 6.7 12.6 4.7e+02 1.2 12.6 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 zf-LITAF-like PF10601.7 MSTRG.48336.1_3 - 0.047 13.8 0.4 0.11 12.7 0.4 1.6 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain PIEZO PF15917.3 MSTRG.48336.1_3 - 0.11 11.8 0.3 0.15 11.4 0.3 1.2 1 0 0 1 1 1 0 Piezo SopD PF11047.6 MSTRG.4032.1_3 - 0.063 12.3 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Salmonella outer protein D IBP39 PF11422.6 MSTRG.25226.1_2 - 0.085 12.5 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 Initiator binding protein 39 kDa GHL15 PF14885.4 MSTRG.47428.1_2 - 0.15 11.8 0.1 0.17 11.7 0.1 1.0 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 RVT_1 PF00078.25 MSTRG.122954.1_3 - 4.8e-06 26.1 0.0 5e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4229 PF14012.4 MSTRG.46005.1_3 - 0.41 10.7 5.8 0.68 9.9 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) RRM_1 PF00076.20 MSTRG.85626.1_2 - 1.9e-22 78.7 0.2 2.8e-22 78.2 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 MSTRG.85626.1_2 - 0.00018 21.3 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.3 MSTRG.85626.1_2 - 0.00043 20.2 0.0 0.00084 19.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.4 MSTRG.85626.1_2 - 0.025 14.7 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter An_peroxidase PF03098.13 MSTRG.75947.1_3 - 7.9e-51 173.1 0.0 8.7e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase RAM PF15320.4 MSTRG.131034.1_2 - 0.028 14.9 0.7 0.051 14.0 0.1 1.8 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.104662.1_2 - 9.9e-23 80.0 1.9 1e-22 80.0 0.6 1.7 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.4 MSTRG.104662.1_2 - 0.00053 19.6 0.0 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.104662.1_2 - 0.0014 19.1 0.6 0.0023 18.4 0.1 1.6 2 0 0 2 2 2 1 Homeodomain-like domain Arg_repressor PF01316.19 MSTRG.104662.1_2 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_28 PF13518.4 MSTRG.104662.1_2 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.4 MSTRG.104662.1_2 - 0.072 12.8 0.4 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Kazal_1 PF00050.19 MSTRG.16954.1_1 - 8.6e-16 57.6 11.5 3.2e-11 42.9 1.2 3.0 3 1 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 MSTRG.16954.1_1 - 1.4e-15 57.0 11.9 1.1e-08 35.0 1.4 2.9 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain CAF20 PF17052.3 MSTRG.14420.1_2 - 0.048 13.7 8.1 0.49 10.4 1.1 2.1 1 1 1 2 2 2 0 Cap associated factor PuR_N PF09182.8 MSTRG.59197.1_2 - 0.0047 16.7 5.6 0.34 10.7 0.9 3.1 1 1 1 2 2 2 2 Bacterial purine repressor, N-terminal CHASE6_C PF17150.2 MSTRG.59197.1_2 - 0.0097 16.4 5.2 0.03 14.8 1.8 2.3 1 1 1 2 2 2 1 C-terminal domain of two-partite extracellular sensor domain DUF4404 PF14357.4 MSTRG.59197.1_2 - 0.1 13.1 0.2 1.3 9.6 0.0 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) IFT57 PF10498.7 MSTRG.59197.1_2 - 0.23 10.3 7.6 0.26 10.1 7.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Cation_ATPase_N PF00690.24 MSTRG.93929.1_3 - 5.4e-19 67.5 0.6 8e-18 63.8 0.1 2.2 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus GPCR_chapero_1 PF11904.6 MSTRG.58321.1_1 - 3.7e-08 33.0 0.1 4.2e-08 32.9 0.1 1.0 1 0 0 1 1 1 1 GPCR-chaperone zf-UBR PF02207.18 MSTRG.101791.1_1 - 1.3e-06 28.3 3.7 1.9e-06 27.8 3.7 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) FRG2 PF15315.4 MSTRG.101791.1_1 - 0.032 14.3 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 TMCO5 PF14992.4 MSTRG.51976.1_3 - 0.35 10.3 1.8 0.45 9.9 1.8 1.1 1 0 0 1 1 1 0 TMCO5 family DUF615 PF04751.12 MSTRG.62539.1_3 - 0.012 15.4 4.4 0.013 15.3 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF615) TLE_N PF03920.13 MSTRG.62539.1_3 - 0.074 13.0 3.3 0.12 12.3 3.3 1.5 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain HTH_38 PF13936.4 MSTRG.122461.1_2 - 3.8e-05 23.3 0.0 4.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain DUF433 PF04255.12 MSTRG.81297.1_2 - 0.15 11.8 0.0 20 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Prot_ATP_ID_OB PF16450.3 MSTRG.22518.1_3 - 0.0014 18.0 0.1 0.0027 17.1 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB/ID domain DivIC PF04977.13 MSTRG.22518.1_3 - 0.0089 15.6 0.4 1 9.1 0.5 2.2 2 0 0 2 2 2 2 Septum formation initiator BLOC1_2 PF10046.7 MSTRG.22518.1_3 - 0.16 12.2 2.3 1.4 9.1 0.5 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GRAB PF10375.7 MSTRG.115113.1_2 - 0.02 14.6 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 GRIP-related Arf-binding domain Ribosomal_L50 PF10501.7 MSTRG.115113.1_2 - 0.046 13.8 0.2 0.062 13.4 0.2 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S DDT PF02791.15 MSTRG.115113.1_2 - 0.1 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 DDT domain FRG1 PF06229.10 MSTRG.89181.1_1 - 0.12 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 FRG1-like domain DUF3480 PF11979.6 MSTRG.49992.1_1 - 3.1e-05 23.1 0.0 4.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) DDE_3 PF13358.4 MSTRG.49992.1_2 - 6.6e-14 51.8 0.0 1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Autoind_bind PF03472.13 MSTRG.13368.1_2 - 0.054 12.9 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 Autoinducer binding domain DUF4817 PF16087.3 MSTRG.84173.1_1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4817) MAD PF05557.11 MSTRG.32000.1_1 - 2.7e-43 148.2 24.8 3.2e-43 147.9 24.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Shugoshin_N PF07558.9 MSTRG.32000.1_1 - 0.021 14.6 0.1 0.021 14.6 0.1 3.6 5 1 0 5 5 5 0 Shugoshin N-terminal coiled-coil region DASH_Dam1 PF08653.8 MSTRG.32000.1_1 - 0.044 13.5 0.5 4.6 7.0 0.0 3.0 2 1 0 2 2 2 0 DASH complex subunit Dam1 HOOK PF05622.10 MSTRG.32000.1_1 - 0.048 11.7 23.6 0.13 10.3 10.0 2.0 1 1 1 2 2 2 0 HOOK protein GAS PF13851.4 MSTRG.32000.1_1 - 0.077 12.2 22.4 0.49 9.6 4.5 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MPS2 PF17060.3 MSTRG.32000.1_1 - 0.13 11.4 16.1 0.011 14.9 10.5 1.7 1 1 1 2 2 2 0 Monopolar spindle protein 2 DUF1664 PF07889.10 MSTRG.32000.1_1 - 0.5 10.2 13.4 1.4 8.8 4.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CxxCxxCC PF03692.13 MSTRG.32000.1_1 - 0.56 10.8 3.1 1.4 9.5 3.1 1.9 1 1 0 1 1 1 0 Putative zinc- or iron-chelating domain Taxilin PF09728.7 MSTRG.32000.1_1 - 0.57 9.2 23.8 0.77 8.8 4.0 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Lebercilin PF15619.4 MSTRG.32000.1_1 - 0.59 9.6 24.7 0.091 12.3 16.4 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Pox_A_type_inc PF04508.10 MSTRG.32000.1_1 - 1.9 8.4 0.0 1.9 8.4 0.0 4.2 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat IncA PF04156.12 MSTRG.32000.1_1 - 2.4 7.8 23.7 1.5e+02 1.9 23.6 2.1 1 1 0 1 1 1 0 IncA protein DUF2570 PF10828.6 MSTRG.32000.1_1 - 3.1 7.6 19.2 0.055 13.2 7.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) PKcGMP_CC PF16808.3 MSTRG.32000.1_1 - 5.6 6.8 0.0 0.18 11.5 1.0 4.9 5 1 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM76 PF16046.3 MSTRG.32000.1_1 - 6.6 5.9 16.8 1.1 8.4 6.0 2.0 1 1 1 2 2 2 0 FAM76 protein Bap31 PF05529.10 MSTRG.32000.1_1 - 6.6 6.1 13.7 0.58 9.6 1.4 2.6 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Globin PF00042.20 MSTRG.6328.1_2 - 0.013 15.9 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Globin CD24 PF14984.4 MSTRG.39810.1_1 - 0.15 12.2 0.5 0.23 11.6 0.5 1.3 1 0 0 1 1 1 0 CD24 protein PINIT PF14324.4 MSTRG.103196.1_1 - 2.2e-07 31.2 0.1 2.4e-07 31.1 0.1 1.0 1 0 0 1 1 1 1 PINIT domain Peptidase_M17 PF00883.19 MSTRG.48342.1_2 - 4.9e-63 213.1 0.0 6.3e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain GMP_PDE_delta PF05351.9 MSTRG.34575.1_1 - 0.061 13.2 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 GMP-PDE, delta subunit Peptidase_A4 PF01828.15 MSTRG.34575.1_2 - 0.002 17.5 0.3 0.0031 16.9 0.3 1.3 1 0 0 1 1 1 1 Peptidase A4 family Clathrin PF00637.18 MSTRG.116142.1_1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.4 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_2 PF07719.15 MSTRG.116142.1_1 - 0.0088 16.0 0.2 0.39 10.8 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.4 MSTRG.116142.1_1 - 0.012 15.7 0.2 0.073 13.2 0.2 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat PPR PF01535.18 MSTRG.116142.1_1 - 0.14 12.3 0.3 36 4.8 0.1 2.9 3 0 0 3 3 3 0 PPR repeat Spectrin PF00435.19 MSTRG.48235.1_2 - 2e-09 37.8 20.1 2.7e-06 27.7 4.0 4.0 4 0 0 4 4 4 2 Spectrin repeat Snapin_Pallidin PF14712.4 MSTRG.48235.1_2 - 0.002 18.4 19.9 0.05 13.9 1.9 5.6 5 1 1 6 6 6 1 Snapin/Pallidin Hrs_helical PF12210.6 MSTRG.48235.1_2 - 0.018 15.5 7.2 0.44 11.0 0.5 4.0 2 2 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate KxDL PF10241.7 MSTRG.48235.1_2 - 0.052 13.7 9.3 0.056 13.6 1.1 3.9 3 1 0 3 3 3 0 Uncharacterized conserved protein ABC_tran_CTD PF16326.3 MSTRG.48235.1_2 - 0.063 13.4 0.9 0.063 13.4 0.9 5.5 4 2 2 6 6 6 0 ABC transporter C-terminal domain ATP_sub_h PF10775.7 MSTRG.48235.1_2 - 0.1 12.5 0.7 3.9 7.4 0.2 2.7 2 0 0 2 2 2 0 ATP synthase complex subunit h DUF3829 PF12889.5 MSTRG.48235.1_2 - 0.33 10.2 7.3 14 4.8 1.3 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3829) APG6 PF04111.10 MSTRG.48235.1_2 - 1.6 7.9 23.6 1.3 8.2 3.9 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 CorA PF01544.16 MSTRG.48235.1_2 - 2.7 7.1 11.3 0.19 10.9 1.4 3.1 1 1 3 4 4 4 0 CorA-like Mg2+ transporter protein IPK PF03770.14 MSTRG.48235.1_2 - 2.7 7.7 7.0 3.6 7.2 0.1 2.9 3 1 1 4 4 4 0 Inositol polyphosphate kinase DUF4407 PF14362.4 MSTRG.48235.1_2 - 2.8 7.1 17.7 1.6 7.9 12.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Atg14 PF10186.7 MSTRG.48235.1_2 - 3.2 6.6 17.7 0.034 13.1 1.2 2.8 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.10 MSTRG.48235.1_2 - 5.3 5.3 11.7 0.2 10.1 4.0 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family FliD_N PF02465.16 MSTRG.48235.1_2 - 5.7 7.6 9.9 36 5.0 0.8 4.2 2 2 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus BLOC1_2 PF10046.7 MSTRG.48235.1_2 - 7.6 6.8 18.4 18 5.6 0.9 5.1 4 1 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bcl-2 PF00452.17 MSTRG.80727.1_2 - 1.8e-20 73.2 0.5 2.2e-20 72.9 0.5 1.1 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Bcl-2_3 PF15286.4 MSTRG.80727.1_2 - 0.015 15.8 0.1 0.022 15.3 0.1 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like GBP_PSP PF02425.13 MSTRG.80727.1_3 - 0.00084 18.8 4.7 0.0013 18.2 4.7 1.2 1 0 0 1 1 1 1 Paralytic/GBP/PSP peptide S1-like PF14444.4 MSTRG.142158.1_1 - 0.02 14.8 1.7 6.7 6.7 0.1 2.7 1 1 2 3 3 3 0 S1-like NfeD PF01957.16 MSTRG.142158.1_1 - 0.4 10.9 7.9 0.89 9.8 7.9 1.7 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF2291 PF10054.7 MSTRG.142158.1_1 - 0.68 9.5 3.9 6.2 6.3 0.5 3.0 1 1 1 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) DUF1534 PF07551.9 MSTRG.142158.1_1 - 1.3 8.6 8.9 11 5.7 0.6 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF1534) CH PF00307.29 MSTRG.8668.1_1 - 5.3e-08 32.9 0.0 5.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL73 PF03554.11 MSTRG.105967.1_3 - 0.098 12.5 1.4 0.15 12.0 0.8 1.6 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein RYDR_ITPR PF01365.19 MSTRG.118273.1_2 - 1e-08 34.7 6.5 1e-08 34.7 6.5 2.0 2 0 0 2 2 2 1 RIH domain Leptin PF02024.13 MSTRG.118273.1_2 - 0.023 14.3 0.1 0.055 13.1 0.1 1.6 1 0 0 1 1 1 0 Leptin DUF3877 PF12993.5 MSTRG.118273.1_2 - 0.044 13.5 1.1 0.23 11.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3336 PF11815.6 MSTRG.118273.1_2 - 0.17 11.4 1.8 1.5 8.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3336) HSL_N PF06350.10 MSTRG.75112.1_2 - 1.2e-50 172.2 0.1 1.3e-50 172.0 0.1 1.0 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus SDH_alpha PF03313.13 MSTRG.25192.1_1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Serine dehydratase alpha chain Exo_endo_phos_2 PF14529.4 MSTRG.123002.1_2 - 7e-05 22.5 0.1 0.00025 20.7 0.1 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Rhodanese PF00581.18 MSTRG.42366.1_1 - 1.6e-12 47.7 0.0 2.5e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Med26 PF08711.9 MSTRG.48211.1_2 - 4.4e-13 48.9 1.1 6.8e-13 48.3 0.3 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Cyt-b5 PF00173.26 MSTRG.43064.1_2 - 2.9e-11 43.2 0.0 5.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.25 MSTRG.67078.1_1 - 8e-44 147.4 4.9 1.1e-16 60.4 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein MBOAT PF03062.17 MSTRG.126020.1_2 - 8.6e-05 21.9 2.5 9e-05 21.8 2.5 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Kelch_1 PF01344.23 MSTRG.36789.1_2 - 2.7e-29 100.3 3.2 3.2e-16 58.5 0.1 3.1 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.4 MSTRG.36789.1_2 - 4.7e-19 67.8 1.3 4.4e-09 36.2 0.0 3.0 1 1 2 3 3 3 3 Kelch motif Kelch_2 PF07646.13 MSTRG.36789.1_2 - 2.7e-17 61.8 0.7 5e-09 35.7 0.0 3.1 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.4 MSTRG.36789.1_2 - 7.6e-12 45.1 0.3 9e-06 25.7 0.0 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.4 MSTRG.36789.1_2 - 4.6e-10 39.1 0.0 1.5e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.4 MSTRG.36789.1_2 - 3.3e-07 30.0 1.6 7.8e-05 22.4 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain BTB_2 PF02214.20 MSTRG.89123.1_3 - 1.9e-23 82.5 0.0 2.8e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.29 MSTRG.89123.1_3 - 0.013 15.5 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Adipokin_hormo PF06377.9 MSTRG.89123.1_3 - 0.034 14.3 0.3 0.21 11.8 0.0 2.3 3 0 0 3 3 3 0 Adipokinetic hormone COesterase PF00135.26 MSTRG.83592.1_1 - 1.1e-37 130.0 1.1 1.2e-37 129.9 1.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family RasGEF PF00617.17 MSTRG.130849.1_3 - 1.4e-32 113.1 1.7 1.5e-32 113.0 1.7 1.0 1 0 0 1 1 1 1 RasGEF domain TPR_2 PF07719.15 MSTRG.12595.1_2 - 9.9e-14 50.2 4.5 0.0022 17.8 0.2 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.26 MSTRG.12595.1_2 - 1.5e-12 46.6 5.9 0.0046 16.6 0.2 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.4 MSTRG.12595.1_2 - 2.6e-10 40.5 0.9 0.18 12.2 0.0 5.0 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.4 MSTRG.12595.1_2 - 2.9e-08 33.1 5.3 0.17 12.0 0.2 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.4 MSTRG.12595.1_2 - 5.3e-08 32.9 1.2 0.0016 18.5 0.0 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.4 MSTRG.12595.1_2 - 1.9e-07 31.0 0.4 0.0097 15.9 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.4 MSTRG.12595.1_2 - 4.8e-07 29.9 0.3 2.3 9.1 0.1 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.4 MSTRG.12595.1_2 - 2.1e-06 27.2 2.3 0.94 9.5 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.5 MSTRG.12595.1_2 - 2.9e-06 27.3 2.8 0.04 14.0 0.3 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC5 PF12862.5 MSTRG.12595.1_2 - 1.4e-05 24.9 0.5 0.00027 20.8 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_11 PF13414.4 MSTRG.12595.1_2 - 6.9e-05 22.3 1.2 0.047 13.3 0.1 4.4 4 1 1 5 5 5 1 TPR repeat TPR_6 PF13174.4 MSTRG.12595.1_2 - 0.00048 20.5 0.6 3.6 8.3 0.0 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.4 MSTRG.12595.1_2 - 0.0045 16.7 1.9 4.7 7.1 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.4 MSTRG.12595.1_2 - 0.0087 16.3 3.1 4.9 7.6 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.4 MSTRG.12595.1_2 - 0.0095 16.1 3.7 1.4 9.1 0.5 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Sds3 PF08598.9 MSTRG.12595.1_2 - 0.021 14.7 1.2 0.026 14.4 1.2 1.2 1 0 0 1 1 1 0 Sds3-like TPR_16 PF13432.4 MSTRG.12595.1_2 - 0.13 12.8 0.5 19 5.9 0.1 3.6 3 1 2 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.7 MSTRG.12595.1_2 - 0.95 8.8 3.8 5.9 6.3 0.2 3.4 4 0 0 4 4 4 0 SHNi-TPR DDE_3 PF13358.4 MSTRG.117290.1_1 - 7.2e-11 41.9 0.3 8.3e-11 41.7 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_1 PF00515.26 MSTRG.125913.1_1 - 9.5e-09 34.6 2.0 0.0032 17.1 0.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.4 MSTRG.125913.1_1 - 2e-05 24.3 0.4 0.11 12.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.15 MSTRG.125913.1_1 - 0.00012 21.8 5.0 0.026 14.5 0.7 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.4 MSTRG.125913.1_1 - 0.00034 20.7 1.5 0.0028 17.8 0.7 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.4 MSTRG.125913.1_1 - 0.0014 18.6 0.2 0.0033 17.4 0.2 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.4 MSTRG.125913.1_1 - 0.0045 16.7 0.4 0.4 10.5 0.1 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.5 MSTRG.125913.1_1 - 0.011 15.8 3.1 0.02 14.9 1.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.4 MSTRG.125913.1_1 - 0.016 14.7 0.0 0.058 13.0 0.0 1.9 1 1 1 2 2 2 0 TPR repeat TPR_17 PF13431.4 MSTRG.125913.1_1 - 0.029 14.6 0.8 0.15 12.4 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.4 MSTRG.125913.1_1 - 0.039 13.8 0.5 2.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.4 MSTRG.125913.1_1 - 0.043 14.5 0.1 7.4 7.6 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat BSMAP PF12280.6 MSTRG.125913.1_1 - 0.058 13.5 1.5 0.091 12.8 1.5 1.4 1 1 0 1 1 1 0 Brain specific membrane anchored protein TPR_19 PF14559.4 MSTRG.125913.1_1 - 0.063 13.7 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.4 MSTRG.125913.1_1 - 0.11 13.1 2.4 0.21 12.2 0.2 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Taxilin PF09728.7 MSTRG.113796.2_3 - 6.8e-16 58.3 9.5 7.4e-16 58.2 9.5 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Alpha-2-MRAP_N PF06400.9 MSTRG.113796.2_3 - 0.021 14.7 1.5 0.048 13.5 0.6 1.8 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain DUF4507 PF14964.4 MSTRG.113796.2_3 - 0.052 12.4 3.4 0.062 12.1 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) RVT_1 PF00078.25 MSTRG.57241.1_2 - 0.041 13.3 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.4 MSTRG.45790.1_2 - 0.0019 17.8 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Spectrin PF00435.19 MSTRG.12551.3_1 - 7.9e-112 366.9 61.3 1.1e-25 90.0 6.1 6.3 6 0 0 6 6 6 6 Spectrin repeat EFhand_Ca_insen PF08726.8 MSTRG.12551.3_1 - 1.5e-24 85.8 0.3 2.8e-24 84.9 0.3 1.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.30 MSTRG.12551.3_1 - 3.4e-11 41.7 0.3 9.4e-06 24.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 MSTRG.12551.3_1 - 4.6e-10 39.7 0.1 1.6e-08 34.8 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.4 MSTRG.12551.3_1 - 3.3e-08 32.7 0.1 0.00057 19.5 0.1 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.4 MSTRG.12551.3_1 - 3.1e-07 29.9 0.0 0.044 13.4 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.4 MSTRG.12551.3_1 - 0.0029 16.9 0.1 3.3 7.3 0.0 2.8 3 0 0 3 3 3 2 EF hand DUF713 PF05218.12 MSTRG.12551.3_1 - 0.39 10.3 4.0 0.11 12.1 0.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF713) DUF4286 PF14114.4 MSTRG.12551.3_1 - 1.8 9.0 4.8 7.4 7.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4286) Spectrin PF00435.19 MSTRG.12551.3_2 - 0 1164.1 182.4 7.9e-29 100.1 3.0 18.1 17 1 0 17 17 17 16 Spectrin repeat SH3_1 PF00018.26 MSTRG.12551.3_2 - 4.4e-15 54.9 0.0 9.3e-15 53.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 MSTRG.12551.3_2 - 6.3e-11 41.8 0.0 1.3e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 MSTRG.12551.3_2 - 8.7e-07 28.4 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.9 MSTRG.12551.3_2 - 0.00052 20.1 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain GvpG PF05120.10 MSTRG.12551.3_2 - 0.0029 17.5 1.2 2.1 8.3 0.1 3.7 2 0 0 2 2 2 2 Gas vesicle protein G Peroxidase_2 PF01328.15 MSTRG.12551.3_2 - 0.12 11.4 0.6 0.23 10.4 0.1 1.6 2 0 0 2 2 2 0 Peroxidase, family 2 DUF3361 PF11841.6 MSTRG.74525.1_3 - 1.2e-43 148.6 3.6 1.4e-43 148.4 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) WAPL PF07814.11 MSTRG.74525.1_3 - 0.0074 15.1 1.2 0.016 14.0 1.1 1.6 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin AAA_16 PF13191.4 MSTRG.102909.1_2 - 0.0014 18.9 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.11 MSTRG.102909.1_2 - 0.0032 16.5 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.4 MSTRG.102909.1_2 - 0.0094 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.4 MSTRG.102909.1_2 - 0.15 12.2 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain Trypan_PARP PF05887.9 MSTRG.128697.1_1 - 0.19 11.6 9.6 0.22 11.4 9.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NPR3 PF03666.11 MSTRG.128697.1_1 - 0.34 9.5 6.3 0.36 9.5 6.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM27 PF15832.3 MSTRG.128697.1_1 - 0.62 10.5 42.9 1.6e+04 -17.2 42.9 3.1 1 1 0 1 1 1 0 FAM27 D and E protein family PRP38_assoc PF12871.5 MSTRG.128697.1_1 - 1.1 9.8 40.4 1.9 9.0 40.4 1.4 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MIP-T3 PF10243.7 MSTRG.128697.1_1 - 2.1 6.9 26.1 2.4 6.7 26.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAM27 PF15832.3 MSTRG.128697.1_3 - 0.0065 16.9 3.2 0.0065 16.9 3.2 3.1 2 1 0 2 2 2 1 FAM27 D and E protein family PRP38_assoc PF12871.5 MSTRG.128697.1_3 - 0.042 14.3 36.1 0.06 13.8 36.1 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SNF2_N PF00176.21 MSTRG.70458.1_3 - 2.2e-15 56.1 0.7 2.7e-15 55.8 0.7 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DDE_3 PF13358.4 MSTRG.58402.1_2 - 2.8e-11 43.2 0.2 3.2e-11 43.0 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1018 PF06252.10 MSTRG.58402.1_2 - 0.086 13.8 0.1 0.25 12.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) 6PF2K PF01591.16 MSTRG.128856.1_2 - 5.7e-101 336.3 0.1 8.2e-101 335.8 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.20 MSTRG.128856.1_2 - 1.6e-35 122.5 0.0 2.4e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.4 MSTRG.128856.1_2 - 8.4e-06 25.9 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.8 MSTRG.128856.1_2 - 0.042 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.10 MSTRG.128856.1_2 - 0.056 12.6 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.4 MSTRG.128856.1_2 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PHD PF00628.27 MSTRG.61260.1_3 - 0.0018 18.0 4.1 0.0035 17.1 4.1 1.5 1 0 0 1 1 1 1 PHD-finger PrmA PF06325.11 MSTRG.11547.1_2 - 1.8e-09 37.3 0.0 1.8e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.4 MSTRG.11547.1_2 - 1.7e-08 34.9 0.1 2e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 MSTRG.11547.1_2 - 4.7e-08 32.8 0.1 5.4e-08 32.6 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.9 MSTRG.11547.1_2 - 2.5e-07 29.8 0.0 2.5e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.4 MSTRG.11547.1_2 - 1.2e-06 28.4 0.0 1.2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.12 MSTRG.11547.1_2 - 6.1e-06 25.7 0.0 6.4e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.10 MSTRG.11547.1_2 - 2.9e-05 24.5 0.0 3.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.17 MSTRG.11547.1_2 - 0.00022 21.2 0.0 0.00024 21.1 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.17 MSTRG.11547.1_2 - 0.00038 20.1 0.0 0.00044 19.9 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.5 MSTRG.11547.1_2 - 0.00079 19.2 0.0 0.00095 19.0 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 MSTRG.11547.1_2 - 0.002 18.7 0.0 0.0022 18.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.18 MSTRG.11547.1_2 - 0.0041 16.3 0.0 0.0041 16.3 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.13 MSTRG.11547.1_2 - 0.0056 16.2 0.0 0.0062 16.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_32 PF13679.4 MSTRG.11547.1_2 - 0.0093 15.8 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.4 MSTRG.11547.1_2 - 0.0095 16.8 0.0 0.011 16.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.7 MSTRG.11547.1_2 - 0.013 15.1 0.0 0.015 14.9 0.0 1.0 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.15 MSTRG.11547.1_2 - 0.026 13.8 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.12 MSTRG.11547.1_2 - 0.033 13.5 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Met_10 PF02475.14 MSTRG.11547.1_2 - 0.042 13.5 0.1 0.045 13.4 0.1 1.0 1 0 0 1 1 1 0 Met-10+ like-protein COX5B PF01215.17 MSTRG.17475.1_1 - 1.9e-27 95.4 0.1 2.7e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb UBA_4 PF14555.4 MSTRG.4851.1_2 - 0.00026 20.6 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain DUF1296 PF06972.9 MSTRG.4851.1_2 - 0.00049 20.1 0.1 0.00049 20.1 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) UBA PF00627.29 MSTRG.4851.1_2 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Pkinase_Tyr PF07714.15 MSTRG.96793.1_2 - 6.5e-46 156.6 0.1 7.1e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 MSTRG.96793.1_2 - 3.7e-23 82.1 0.2 4.7e-23 81.8 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.4 MSTRG.96793.1_2 - 0.0016 17.7 0.1 0.0021 17.3 0.1 1.3 1 1 0 1 1 1 1 Kinase-like HTH_38 PF13936.4 MSTRG.86557.1_1 - 4e-06 26.4 0.1 6e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.86557.1_1 - 5e-05 22.8 0.0 6.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Ribosomal_S13_N PF08069.10 MSTRG.86557.1_1 - 0.0044 16.9 0.5 0.065 13.1 0.1 2.1 1 1 1 2 2 2 1 Ribosomal S13/S15 N-terminal domain PAX PF00292.16 MSTRG.86557.1_1 - 0.01 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain HTH_Tnp_ISL3 PF13542.4 MSTRG.86557.1_1 - 0.026 13.8 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Bot1p PF12298.6 MSTRG.86557.1_1 - 0.039 14.0 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein DUF4269 PF14091.4 MSTRG.86557.1_1 - 0.055 13.6 0.0 0.057 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) HTH_7 PF02796.13 MSTRG.86557.1_1 - 0.08 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_36 PF13730.4 MSTRG.86557.1_1 - 0.11 12.3 0.7 6.4 6.7 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.4 MSTRG.86557.1_1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain C1_2 PF03107.14 MSTRG.35608.1_3 - 0.094 12.9 0.7 3.6 7.9 0.0 2.1 2 0 0 2 2 2 0 C1 domain Roc PF08477.11 MSTRG.18968.1_2 - 0.0083 16.2 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 MSTRG.18968.1_2 - 0.043 13.3 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Ras family MMR_HSR1 PF01926.21 MSTRG.18968.1_2 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase VirE PF05272.9 MSTRG.18968.1_2 - 0.14 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Virulence-associated protein E PAF-AH_p_II PF03403.11 MSTRG.34728.1_3 - 7.1e-151 501.9 0.0 9e-151 501.5 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.5 MSTRG.34728.1_3 - 6e-10 38.3 0.0 1.6e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.9 MSTRG.34728.1_3 - 4.6e-06 25.7 0.0 0.00031 19.7 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.6 MSTRG.34728.1_3 - 2.5e-05 23.5 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.16 MSTRG.34728.1_3 - 0.0002 20.8 0.0 0.0013 18.1 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.19 MSTRG.34728.1_3 - 0.001 18.5 0.0 0.0023 17.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.5 MSTRG.34728.1_3 - 0.0068 16.0 0.0 0.024 14.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.5 MSTRG.34728.1_3 - 0.036 14.5 0.0 0.19 12.2 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family MBD PF01429.17 MSTRG.112694.1_1 - 1.6e-12 46.8 0.0 2.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain IRF PF00605.15 MSTRG.140447.1_3 - 1.1e-42 144.4 0.3 1.7e-42 143.8 0.3 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor CagY_I PF14585.4 MSTRG.140447.1_3 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 CagY type 1 repeat CDK2AP PF09806.7 MSTRG.8004.1_2 - 5.9e-19 68.9 0.0 7.5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein FYTT PF07078.9 MSTRG.86637.1_1 - 7.6e-11 41.8 1.1 8.7e-11 41.6 1.1 1.1 1 0 0 1 1 1 1 Forty-two-three protein ROKNT PF08067.9 MSTRG.132207.4_2 - 2.2e-06 27.7 3.0 3.6e-06 27.0 3.0 1.3 1 0 0 1 1 1 1 ROKNT (NUC014) domain SpoVAD PF07451.9 MSTRG.132207.4_3 - 0.041 12.5 0.2 0.05 12.2 0.2 1.0 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) UPF0239 PF06783.9 MSTRG.122298.1_3 - 0.051 13.6 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Toxin_4 PF00706.15 MSTRG.122298.1_3 - 0.15 12.4 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Anenome neurotoxin RTP801_C PF07809.9 MSTRG.141536.1_1 - 2.5e-34 117.8 0.0 4e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 RTP801 C-terminal region RTBV_P46 PF06216.9 MSTRG.119837.1_3 - 0.00022 20.1 0.6 0.00027 19.8 0.6 1.1 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein IFT57 PF10498.7 MSTRG.119837.1_3 - 0.00024 20.1 4.0 0.00027 19.9 4.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 TMF_DNA_bd PF12329.6 MSTRG.119837.1_3 - 0.00082 19.2 23.4 0.0025 17.6 9.6 2.5 2 1 1 3 3 2 2 TATA element modulatory factor 1 DNA binding HMMR_N PF15905.3 MSTRG.119837.1_3 - 0.0011 18.4 12.0 0.0013 18.1 12.0 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal zf-C4H2 PF10146.7 MSTRG.119837.1_3 - 0.0022 18.2 0.5 0.0035 17.5 0.5 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein Baculo_PEP_C PF04513.10 MSTRG.119837.1_3 - 0.0023 17.9 1.0 0.0049 16.8 0.8 1.7 2 0 0 2 2 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.11 MSTRG.119837.1_3 - 0.005 16.8 12.9 0.38 10.7 8.3 2.2 1 1 1 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 DUF1451 PF07295.9 MSTRG.119837.1_3 - 0.01 15.8 2.4 0.023 14.6 2.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon containing domain FliD_C PF07195.10 MSTRG.119837.1_3 - 0.014 14.7 2.7 0.014 14.7 2.7 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ABC_tran_CTD PF16326.3 MSTRG.119837.1_3 - 0.016 15.3 7.0 0.016 15.3 7.0 3.2 1 1 2 3 3 3 0 ABC transporter C-terminal domain ATG16 PF08614.9 MSTRG.119837.1_3 - 0.019 15.0 19.6 0.14 12.2 5.0 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.6 MSTRG.119837.1_3 - 0.023 14.8 16.0 1.1 9.4 0.6 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.10 MSTRG.119837.1_3 - 0.024 13.9 8.4 0.027 13.7 8.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Exonuc_VII_L PF02601.13 MSTRG.119837.1_3 - 0.028 13.9 3.3 0.034 13.6 3.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4172 PF13776.4 MSTRG.119837.1_3 - 0.033 14.4 1.5 0.083 13.1 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4172) DUF3584 PF12128.6 MSTRG.119837.1_3 - 0.036 11.5 6.9 0.037 11.4 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TSNAXIP1_N PF15739.3 MSTRG.119837.1_3 - 0.036 14.3 1.2 0.036 14.3 1.2 2.4 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus AAA_13 PF13166.4 MSTRG.119837.1_3 - 0.039 12.5 6.4 0.05 12.1 6.4 1.1 1 0 0 1 1 1 0 AAA domain DUF885 PF05960.9 MSTRG.119837.1_3 - 0.044 13.3 4.3 0.056 12.9 4.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF342 PF03961.11 MSTRG.119837.1_3 - 0.051 12.0 6.5 0.068 11.6 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CREPT PF16566.3 MSTRG.119837.1_3 - 0.067 13.2 10.3 1.3 9.1 1.0 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Prominin PF05478.9 MSTRG.119837.1_3 - 0.068 11.0 1.9 0.093 10.5 1.9 1.2 1 0 0 1 1 1 0 Prominin Reo_sigmaC PF04582.10 MSTRG.119837.1_3 - 0.07 12.4 3.4 0.081 12.2 2.1 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ApoLp-III PF07464.9 MSTRG.119837.1_3 - 0.072 13.0 9.5 0.17 11.9 9.5 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) EzrA PF06160.10 MSTRG.119837.1_3 - 0.076 11.1 10.3 0.098 10.7 10.3 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2968 PF11180.6 MSTRG.119837.1_3 - 0.08 12.5 6.3 0.1 12.1 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) SYCE1 PF15233.4 MSTRG.119837.1_3 - 0.082 12.8 17.8 1.9 8.4 3.1 2.4 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 FAM76 PF16046.3 MSTRG.119837.1_3 - 0.12 11.5 13.4 0.84 8.8 13.4 1.9 1 1 0 1 1 1 0 FAM76 protein Spc7 PF08317.9 MSTRG.119837.1_3 - 0.13 11.0 17.8 0.33 9.7 17.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Allexi_40kDa PF05549.9 MSTRG.119837.1_3 - 0.13 11.6 1.8 0.2 11.0 1.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Syntaxin-6_N PF09177.9 MSTRG.119837.1_3 - 0.14 12.6 9.0 0.2 12.1 6.3 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Nsp1_C PF05064.11 MSTRG.119837.1_3 - 0.15 11.7 6.1 0.19 11.4 5.2 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region LUC7 PF03194.13 MSTRG.119837.1_3 - 0.15 11.5 4.7 0.2 11.1 4.7 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Cob_adeno_trans PF01923.16 MSTRG.119837.1_3 - 0.2 11.6 5.2 0.15 12.1 3.5 1.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Cauli_AT PF03233.11 MSTRG.119837.1_3 - 0.21 11.4 5.2 0.42 10.4 5.3 1.5 2 0 0 2 2 1 0 Aphid transmission protein IL28A PF15177.4 MSTRG.119837.1_3 - 0.22 11.2 5.9 0.34 10.6 4.0 2.0 1 1 1 2 2 2 0 Interleukin-28A AAA_32 PF13654.4 MSTRG.119837.1_3 - 0.3 9.7 8.8 0.37 9.4 8.8 1.1 1 0 0 1 1 1 0 AAA domain Mt_ATP-synt_D PF05873.10 MSTRG.119837.1_3 - 0.31 10.7 4.0 0.48 10.1 4.0 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) PKcGMP_CC PF16808.3 MSTRG.119837.1_3 - 0.4 10.4 0.1 0.4 10.4 0.1 3.4 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phage_GPO PF05929.9 MSTRG.119837.1_3 - 0.4 10.1 9.3 0.38 10.2 8.0 1.6 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.4 MSTRG.119837.1_3 - 0.42 9.8 9.1 0.82 8.8 6.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nup54 PF13874.4 MSTRG.119837.1_3 - 0.44 10.5 6.0 0.72 9.8 6.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.17 MSTRG.119837.1_3 - 0.51 8.0 1.5 0.53 8.0 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.10 MSTRG.119837.1_3 - 0.53 10.2 15.2 0.16 11.9 9.8 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.8 MSTRG.119837.1_3 - 0.54 10.3 10.3 0.59 10.2 9.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.4 MSTRG.119837.1_3 - 0.56 9.4 15.6 1 8.5 15.7 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding T3SS_needle_E PF08988.8 MSTRG.119837.1_3 - 0.65 10.1 8.6 0.9 9.6 1.2 2.9 1 1 2 3 3 2 0 Type III secretion system, cytoplasmic E component of needle HAUS6_N PF14661.4 MSTRG.119837.1_3 - 0.88 9.0 9.1 1.3 8.5 9.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fez1 PF06818.13 MSTRG.119837.1_3 - 0.97 9.7 14.1 2 8.7 13.6 1.7 1 1 0 1 1 1 0 Fez1 FlxA PF14282.4 MSTRG.119837.1_3 - 1.1 9.2 10.7 2.8 7.9 10.7 1.8 1 1 0 1 1 1 0 FlxA-like protein Prefoldin_2 PF01920.18 MSTRG.119837.1_3 - 1.8 8.5 19.7 0.58 10.0 8.2 2.9 1 1 2 3 3 3 0 Prefoldin subunit DUF16 PF01519.14 MSTRG.119837.1_3 - 1.8 8.9 12.3 5 7.5 8.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.10 MSTRG.119837.1_3 - 2.2 8.8 13.0 3.4 8.2 6.4 2.9 2 1 1 3 3 3 0 SlyX NPV_P10 PF05531.10 MSTRG.119837.1_3 - 2.5 8.5 8.5 9.8 6.6 4.6 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF883 PF05957.11 MSTRG.119837.1_3 - 2.5 8.6 9.1 6 7.4 0.3 2.9 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) 5_nucleotid PF05761.12 MSTRG.119837.1_3 - 2.8 6.6 5.4 3.7 6.2 5.4 1.1 1 0 0 1 1 1 0 5' nucleotidase family ENT PF03735.12 MSTRG.119837.1_3 - 2.8 8.0 7.3 1.6 8.8 1.4 2.6 1 1 2 3 3 3 0 ENT domain DUF3552 PF12072.6 MSTRG.119837.1_3 - 2.8 7.2 19.6 5.9 6.1 5.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) MCU PF04678.11 MSTRG.119837.1_3 - 3 7.8 9.2 4.5 7.2 8.8 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF4200 PF13863.4 MSTRG.119837.1_3 - 3 8.1 17.3 29 4.9 17.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2203 PF09969.7 MSTRG.119837.1_3 - 3.1 8.4 8.5 6 7.5 5.2 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ZapB PF06005.10 MSTRG.119837.1_3 - 3.3 8.1 15.0 1.9 8.9 10.8 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DUF4140 PF13600.4 MSTRG.119837.1_3 - 3.4 8.1 13.7 2.2e+02 2.2 13.7 2.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.11 MSTRG.119837.1_3 - 3.5 7.3 14.3 5.4 6.6 4.7 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.20 MSTRG.119837.1_3 - 3.6 7.7 16.2 1.6 8.9 9.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.15 MSTRG.119837.1_3 - 3.8 7.3 15.3 0.38 10.5 6.7 2.8 1 1 1 2 2 2 0 Prefoldin subunit DUF641 PF04859.10 MSTRG.119837.1_3 - 5.6 7.2 13.7 22 5.3 0.8 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Atg14 PF10186.7 MSTRG.119837.1_3 - 6.5 5.6 13.7 37 3.1 13.7 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.10 MSTRG.119837.1_3 - 8.1 6.3 10.0 10 6.0 7.4 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) ACCA PF03255.12 MSTRG.119837.1_3 - 8.2 6.2 8.3 3.7 7.3 5.4 1.8 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit KfrA_N PF11740.6 MSTRG.119837.1_3 - 8.8 6.9 12.7 73 4.0 11.2 2.7 1 1 1 2 2 1 0 Plasmid replication region DNA-binding N-term adh_short PF00106.23 MSTRG.18694.1_3 - 1.1e-05 24.9 0.2 2.8e-05 23.5 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 MSTRG.18694.1_3 - 0.0018 17.8 0.2 0.017 14.5 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RCC1 PF00415.16 MSTRG.72909.1_3 - 1.4e-59 198.3 9.4 1.6e-17 63.7 0.1 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 MSTRG.72909.1_3 - 3.8e-31 106.1 16.0 7.5e-09 35.1 1.2 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BBS1 PF14779.4 MSTRG.28292.1_1 - 0.039 13.2 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DUF1891 PF09004.8 MSTRG.21775.1_1 - 7e-06 25.4 0.7 7e-06 25.4 0.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1891) Ribosomal_S5 PF00333.18 MSTRG.18446.1_1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain PEN-2 PF10251.7 MSTRG.40527.1_2 - 0.28 11.5 5.4 0.42 10.9 5.4 1.4 1 1 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase TMEM154 PF15102.4 MSTRG.70896.1_2 - 8.7e-11 41.8 0.2 1.1e-10 41.5 0.2 1.1 1 0 0 1 1 1 1 TMEM154 protein family CIMR PF00878.16 MSTRG.31723.1_3 - 5.1e-51 172.4 6.0 5.5e-38 130.1 2.4 2.0 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.8 MSTRG.31723.1_3 - 2.8e-11 43.6 7.5 2.2e-10 40.7 2.3 2.2 1 1 1 2 2 2 2 Autophagy-related protein 27 NUC205 PF08168.9 MSTRG.31723.1_3 - 0.11 11.9 0.1 0.3 10.5 0.1 1.7 1 0 0 1 1 1 0 NUC205 domain Cation_efflux PF01545.19 MSTRG.96636.1_3 - 0.0001 21.9 1.8 0.00014 21.5 1.8 1.2 1 0 0 1 1 1 1 Cation efflux family BTB_3 PF16017.3 MSTRG.10238.1_3 - 2.9e-50 168.6 0.0 3.3e-50 168.5 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.20 MSTRG.10238.1_3 - 0.00026 21.2 0.0 0.00041 20.5 0.0 1.3 1 1 0 1 1 1 1 BTB/POZ domain Exo_endo_phos_2 PF14529.4 MSTRG.105297.1_2 - 0.00011 22.0 0.1 0.00097 18.8 0.1 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Thioesterase PF00975.18 MSTRG.2861.1_3 - 1.2e-05 25.4 0.0 1.4e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.6 MSTRG.2861.1_3 - 3.3e-05 23.1 0.0 3.7e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.18 MSTRG.2861.1_3 - 0.00019 21.1 0.0 0.00021 20.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.11 MSTRG.2861.1_3 - 0.0024 17.6 0.0 0.0025 17.6 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 MSTRG.2861.1_3 - 0.015 15.8 0.0 0.015 15.8 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.7 MSTRG.2861.1_3 - 0.11 11.2 0.0 0.12 11.1 0.0 1.0 1 0 0 1 1 1 0 Steryl acetyl hydrolase HemolysinCabind PF00353.17 MSTRG.10786.1_3 - 8.2 7.2 12.3 13 6.6 0.5 3.2 3 0 0 3 3 3 0 Haemolysin-type calcium-binding repeat (2 copies) DUF4371 PF14291.4 MSTRG.17097.1_1 - 0.001 18.7 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) SNF PF00209.16 MSTRG.36243.1_3 - 7.6e-08 31.4 2.4 8.9e-08 31.1 2.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Tat PF00539.16 MSTRG.80761.1_1 - 0.023 14.7 4.1 0.078 13.0 4.1 1.9 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) EVC2_like PF12297.6 MSTRG.76952.1_1 - 0.44 9.0 1.0 0.4 9.2 1.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF1993 PF09351.8 MSTRG.106593.1_2 - 0.16 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) CARD PF00619.19 MSTRG.83570.1_1 - 1.5e-16 60.0 1.1 2.4e-16 59.4 1.1 1.3 1 0 0 1 1 1 1 Caspase recruitment domain TGF_beta PF00019.18 MSTRG.98606.1_1 - 3.1e-14 53.6 0.0 4.1e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain HOOK PF05622.10 MSTRG.66092.1_1 - 0.00045 18.4 22.2 0.0011 17.1 22.2 1.5 1 1 0 1 1 1 1 HOOK protein Bacillus_HBL PF05791.9 MSTRG.66092.1_1 - 0.00073 19.2 2.0 0.00073 19.2 2.0 2.4 2 1 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) TolA_bind_tri PF16331.3 MSTRG.66092.1_1 - 0.0011 18.8 0.4 0.0011 18.8 0.4 4.2 2 1 2 4 4 4 1 TolA binding protein trimerisation DUF1664 PF07889.10 MSTRG.66092.1_1 - 0.0019 18.0 14.7 0.011 15.6 0.5 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.10 MSTRG.66092.1_1 - 0.0034 17.3 0.4 0.0034 17.3 0.4 2.7 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.9 MSTRG.66092.1_1 - 0.0053 14.7 1.4 0.0053 14.7 1.4 2.0 1 1 1 2 2 2 1 Prominin DUF4618 PF15397.4 MSTRG.66092.1_1 - 0.0085 15.4 18.8 0.018 14.3 0.8 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4618) Cytochrom_C_2 PF01322.18 MSTRG.66092.1_1 - 0.012 16.4 0.6 0.77 10.5 0.5 2.3 1 1 1 2 2 2 0 Cytochrome C' OmpH PF03938.12 MSTRG.66092.1_1 - 0.016 15.1 22.7 0.021 14.7 1.5 3.0 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.10 MSTRG.66092.1_1 - 0.02 15.2 8.5 0.58 10.5 0.0 3.7 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.9 MSTRG.66092.1_1 - 0.021 14.9 3.4 2.4 8.4 0.0 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.18 MSTRG.66092.1_1 - 0.027 14.3 24.2 0.39 10.6 4.8 3.8 3 1 1 4 4 4 0 Prefoldin subunit KASH_CCD PF14662.4 MSTRG.66092.1_1 - 0.038 13.7 22.0 0.073 12.8 21.4 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Laminin_II PF06009.10 MSTRG.66092.1_1 - 0.044 13.7 0.7 0.044 13.7 0.7 3.0 1 1 2 3 3 3 0 Laminin Domain II IncA PF04156.12 MSTRG.66092.1_1 - 0.12 12.0 25.4 0.018 14.7 8.4 2.2 1 1 1 2 2 2 0 IncA protein FTCD_C PF04961.10 MSTRG.66092.1_1 - 0.12 11.9 3.4 0.76 9.4 0.1 2.4 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase BLOC1_2 PF10046.7 MSTRG.66092.1_1 - 0.18 12.0 12.9 0.56 10.4 0.1 3.9 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.9 MSTRG.66092.1_1 - 0.7 8.6 23.7 0.41 9.3 12.6 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.6 MSTRG.66092.1_1 - 0.78 8.9 23.3 0.18 10.9 3.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF4407 PF14362.4 MSTRG.66092.1_1 - 0.8 8.9 13.2 2.4 7.3 13.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Taxilin PF09728.7 MSTRG.66092.1_1 - 0.81 8.8 23.4 3 6.9 23.4 2.3 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Prefoldin PF02996.15 MSTRG.66092.1_1 - 1.1 9.1 16.3 1.2 8.9 0.0 3.8 2 1 2 4 4 4 0 Prefoldin subunit FUSC PF04632.10 MSTRG.66092.1_1 - 1.1 7.6 5.8 2 6.7 5.8 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family KxDL PF10241.7 MSTRG.66092.1_1 - 1.4 9.1 22.8 3.1 8.0 1.5 4.1 3 1 1 4 4 4 0 Uncharacterized conserved protein Jnk-SapK_ap_N PF09744.7 MSTRG.66092.1_1 - 2.2 8.4 26.4 0.23 11.5 12.0 2.7 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-K PF11802.6 MSTRG.66092.1_1 - 2.2 7.6 18.7 0.17 11.3 2.3 3.0 2 1 1 3 3 3 0 Centromere-associated protein K TPR_MLP1_2 PF07926.10 MSTRG.66092.1_1 - 3 7.8 27.9 2.4 8.1 6.7 3.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ERM PF00769.17 MSTRG.66092.1_1 - 3.1 7.4 25.2 22 4.7 25.2 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF883 PF05957.11 MSTRG.66092.1_1 - 3.1 8.3 12.3 0.32 11.5 1.7 3.3 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.8 MSTRG.66092.1_1 - 3.7 7.6 17.7 1.4 8.9 1.2 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.11 MSTRG.66092.1_1 - 4 7.7 21.9 13 6.1 3.4 2.9 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0449 PF15136.4 MSTRG.66092.1_1 - 4.3 7.7 23.2 1.3 9.4 1.0 3.8 2 1 2 4 4 4 0 Uncharacterised protein family UPF0449 APG6 PF04111.10 MSTRG.66092.1_1 - 4.7 6.4 21.6 0.056 12.7 8.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 HMMR_N PF15905.3 MSTRG.66092.1_1 - 5.6 6.2 26.0 0.9 8.8 11.4 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal MerR-DNA-bind PF09278.9 MSTRG.66092.1_1 - 6.6 7.2 14.5 0.45 11.0 0.8 3.5 3 1 1 4 4 3 0 MerR, DNA binding Exonuc_VII_L PF02601.13 MSTRG.66092.1_1 - 6.9 6.0 18.6 94 2.3 18.6 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.7 MSTRG.66092.1_1 - 8.5 7.0 13.9 5.8 7.5 0.9 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF16 PF01519.14 MSTRG.66092.1_1 - 9.6 6.6 16.0 1.5 9.2 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function DUF16 RecG_N PF17190.2 MSTRG.66092.1_1 - 9.8 6.9 10.7 17 6.1 1.4 3.2 1 1 1 3 3 3 0 RecG N-terminal helical domain Exo_endo_phos PF03372.21 MSTRG.43667.1_1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF2360 PF10152.7 MSTRG.40008.1_2 - 1e-12 48.6 1.0 1.6e-12 48.0 1.0 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Ornatin PF02088.13 MSTRG.133096.1_2 - 0.14 11.8 6.4 13 5.5 0.1 3.2 2 1 0 2 2 2 0 Ornatin GAPT PF11770.6 MSTRG.143311.1_1 - 0.0082 15.9 0.4 0.012 15.4 0.4 1.3 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) DUF4381 PF14316.4 MSTRG.143311.1_1 - 0.015 15.4 0.3 0.02 15.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Mlo PF03094.13 MSTRG.143311.1_1 - 0.022 13.0 2.9 0.027 12.7 2.9 1.1 1 0 0 1 1 1 0 Mlo family PsbN PF02468.13 MSTRG.143311.1_1 - 0.033 13.9 2.2 0.054 13.2 2.2 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) DUF2140 PF09911.7 MSTRG.143311.1_1 - 0.041 13.3 2.0 0.057 12.8 2.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) MAP17 PF15807.3 MSTRG.143311.1_1 - 0.3 11.1 5.9 0.13 12.3 3.1 1.7 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2681 PF10883.6 MSTRG.143311.1_1 - 0.61 10.4 5.4 0.1 12.9 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) zf-RING_4 PF14570.4 MSTRG.17057.1_1 - 0.052 13.2 0.3 0.097 12.3 0.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Aldedh PF00171.20 MSTRG.60226.1_2 - 2.3e-37 128.5 0.2 2.5e-37 128.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PWWP PF00855.15 MSTRG.86031.1_2 - 1e-12 48.2 0.1 1.9e-12 47.3 0.1 1.5 1 1 0 1 1 1 1 PWWP domain TrbC_Ftype PF09673.8 MSTRG.86031.1_2 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein Dus PF01207.15 MSTRG.119889.1_3 - 0.12 11.3 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) BH4 PF02180.15 MSTRG.29622.1_1 - 0.12 12.1 0.0 4.3 7.1 0.0 2.5 3 0 0 3 3 3 0 Bcl-2 homology region 4 PSRP-3_Ycf65 PF04839.11 MSTRG.29622.1_2 - 0.075 13.1 0.5 0.13 12.4 0.5 1.5 1 1 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Fibrinogen_C PF00147.16 MSTRG.140901.1_3 - 6.8e-32 110.9 3.9 8.3e-32 110.6 3.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Ldl_recept_b PF00058.15 MSTRG.34365.1_2 - 4.5e-26 90.9 1.4 2.8e-15 56.4 0.3 3.0 3 0 0 3 3 3 3 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.3 MSTRG.34365.1_2 - 0.022 13.8 0.0 0.031 13.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5050) SGL PF08450.10 MSTRG.34365.1_2 - 0.054 12.9 0.1 0.13 11.6 0.1 1.5 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Exo_endo_phos_2 PF14529.4 MSTRG.138490.1_1 - 0.047 13.4 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.21 MSTRG.138490.1_1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.4 MSTRG.38804.1_3 - 0.0037 17.0 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase C1q PF00386.19 MSTRG.135446.1_1 - 8.3e-12 45.3 0.1 9.8e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.16 MSTRG.135446.1_1 - 3.7e-05 23.2 9.3 5.6e-05 22.7 9.3 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF1731 PF08338.9 MSTRG.66689.1_1 - 1.6e-18 66.1 0.0 2.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Fibrinogen_C PF00147.16 MSTRG.60326.1_1 - 5.2e-60 202.9 1.1 7.5e-60 202.3 1.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4407 PF14362.4 MSTRG.60326.1_1 - 0.0092 15.2 9.7 0.0073 15.6 8.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Spc7 PF08317.9 MSTRG.60326.1_1 - 0.085 11.6 14.6 0.022 13.5 6.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Nup54 PF13874.4 MSTRG.60326.1_1 - 0.087 12.8 16.0 0.034 14.1 3.8 2.7 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DUF4795 PF16043.3 MSTRG.60326.1_1 - 0.24 10.9 10.7 0.46 9.9 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Leu_zip PF15294.4 MSTRG.60326.1_1 - 0.32 10.3 12.5 0.31 10.4 10.4 1.9 1 1 0 1 1 1 0 Leucine zipper DUF2524 PF10732.7 MSTRG.60326.1_1 - 0.5 10.6 7.3 1.1 9.5 7.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Atg14 PF10186.7 MSTRG.60326.1_1 - 0.5 9.3 13.5 0.32 9.9 10.7 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3552 PF12072.6 MSTRG.60326.1_1 - 0.67 9.2 14.2 0.0094 15.3 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Lebercilin PF15619.4 MSTRG.60326.1_1 - 1.2 8.7 16.3 1.9 7.9 2.3 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.10 MSTRG.60326.1_1 - 1.2 9.5 17.5 0.033 14.5 6.2 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Bap31 PF05529.10 MSTRG.60326.1_1 - 1.8 8.0 7.6 1.9 7.9 5.1 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like APG6 PF04111.10 MSTRG.60326.1_1 - 2.3 7.4 13.6 2.1 7.5 11.4 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 Mod_r PF07200.11 MSTRG.60326.1_1 - 3.7 7.5 10.5 0.29 11.1 2.0 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2968 PF11180.6 MSTRG.60326.1_1 - 8 6.0 14.2 3.4 7.2 4.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) zf-C2H2 PF00096.24 MSTRG.140710.1_3 - 5.1e-11 42.3 16.1 2.6e-06 27.5 1.5 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.140710.1_3 - 3.6e-09 36.5 20.3 1.3e-07 31.6 2.1 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.140710.1_3 - 1e-06 28.9 13.8 0.0017 18.9 1.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3268 PF11672.6 MSTRG.140710.1_3 - 0.00011 22.4 1.1 0.00014 22.1 1.1 1.2 1 0 0 1 1 1 1 zinc-finger-containing domain zf-C2H2_jaz PF12171.6 MSTRG.140710.1_3 - 0.0082 16.3 15.8 0.057 13.6 1.5 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.4 MSTRG.140710.1_3 - 0.01 15.4 9.8 0.01 15.4 9.8 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.5 MSTRG.140710.1_3 - 0.084 13.1 1.6 0.084 13.1 1.6 2.7 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.13 MSTRG.140710.1_3 - 0.096 12.6 3.0 2.5 8.1 0.3 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.4 MSTRG.140710.1_3 - 0.1 12.4 0.7 0.1 12.4 0.7 2.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type GAGA PF09237.9 MSTRG.140710.1_3 - 0.13 12.0 2.9 0.1 12.3 1.7 1.5 1 1 0 1 1 1 0 GAGA factor YyzF PF14116.4 MSTRG.140710.1_3 - 0.24 11.3 4.3 1.4 8.8 0.2 2.2 2 0 0 2 2 2 0 YyzF-like protein CpXC PF14353.4 MSTRG.140710.1_3 - 0.28 11.1 0.1 0.28 11.1 0.1 1.9 1 1 1 2 2 2 0 CpXC protein zf-C2H2_7 PF15269.4 MSTRG.140710.1_3 - 0.29 11.1 8.0 0.091 12.7 4.2 1.9 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_2 PF12756.5 MSTRG.140710.1_3 - 0.31 11.3 12.5 0.94 9.7 7.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.13 MSTRG.140710.1_3 - 0.52 10.3 12.9 3.7 7.5 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.8 MSTRG.140710.1_3 - 0.59 10.2 5.6 8 6.5 5.9 2.1 1 1 1 2 2 2 0 Zinc ribbon domain PyrI_C PF02748.13 MSTRG.140710.1_3 - 1.2 8.9 5.5 6.1 6.7 0.2 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.3 MSTRG.140710.1_3 - 2 8.8 11.6 6 7.3 11.6 1.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.24 MSTRG.65537.1_1 - 3.1e-11 42.9 22.3 8.4e-05 22.7 3.3 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.65537.1_1 - 2e-10 40.5 8.7 1.6e-06 28.1 0.8 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.65537.1_1 - 6.2e-07 29.6 21.0 0.0078 16.8 0.5 4.0 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.65537.1_1 - 4.3e-05 23.6 5.5 0.65 10.2 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 MSTRG.65537.1_1 - 0.00045 19.8 7.2 0.8 9.4 0.1 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.4 MSTRG.65537.1_1 - 0.005 16.6 12.7 0.48 10.3 0.8 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 MSTRG.65537.1_1 - 0.0076 16.2 5.4 0.058 13.4 2.4 2.4 2 0 0 2 2 2 1 Zinc ribbon domain zf-met PF12874.5 MSTRG.65537.1_1 - 0.01 16.1 7.1 0.31 11.3 1.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.4 MSTRG.65537.1_1 - 0.012 15.2 2.2 0.012 15.2 2.2 4.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2HE PF16278.3 MSTRG.65537.1_1 - 0.017 15.4 14.0 0.75 10.2 2.8 3.4 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.3 MSTRG.65537.1_1 - 0.039 14.1 1.7 0.039 14.1 1.7 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon XPA_N PF01286.16 MSTRG.65537.1_1 - 0.089 12.7 7.3 10 6.1 0.1 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zinc_ribbon_9 PF14369.4 MSTRG.65537.1_1 - 0.17 12.0 5.2 37 4.6 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-AN1 PF01428.14 MSTRG.65537.1_1 - 0.24 11.5 8.0 2.2 8.4 0.3 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger Copper-fist PF00649.16 MSTRG.65537.1_1 - 0.28 10.6 4.1 5.4 6.5 0.1 2.6 2 0 0 2 2 2 0 Copper fist DNA binding domain zf-C2HC_2 PF13913.4 MSTRG.65537.1_1 - 0.33 10.8 13.4 1.2 9.0 0.3 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_1 PF00130.20 MSTRG.65537.1_1 - 0.46 10.3 8.7 2.3 8.0 3.9 3.0 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.10 MSTRG.65537.1_1 - 0.72 9.8 5.9 15 5.5 2.6 2.9 1 1 2 3 3 3 0 zinc-ribbons DZR PF12773.5 MSTRG.65537.1_1 - 0.72 9.8 7.7 13 5.8 7.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.16 MSTRG.65537.1_1 - 8.7 6.2 11.0 7.4 6.4 1.3 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-H2C2_2 PF13465.4 MSTRG.65537.1_2 - 3.5e-17 61.9 7.2 8.8e-06 25.8 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.65537.1_2 - 0.00066 20.2 10.6 0.74 10.7 0.2 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.65537.1_2 - 0.015 15.1 5.9 1.8 8.5 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.24 MSTRG.65537.1_2 - 0.14 12.5 13.3 1.7 9.2 0.0 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.3 MSTRG.65537.1_2 - 0.23 11.6 3.1 0.3 11.3 1.1 2.3 2 1 0 2 2 2 0 C2H2-type zinc ribbon Desulfoferrod_N PF06397.10 MSTRG.65537.1_2 - 0.36 10.4 3.0 5.5 6.6 0.1 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Zn-ribbon_8 PF09723.8 MSTRG.65537.1_2 - 0.53 10.3 4.6 13 5.9 1.4 2.6 1 1 1 2 2 2 0 Zinc ribbon domain FYVE PF01363.19 MSTRG.65537.1_2 - 1.1 9.3 7.0 9.7 6.3 4.1 3.0 2 1 0 2 2 2 0 FYVE zinc finger zf-H2C2_2 PF13465.4 MSTRG.65537.1_3 - 2.9e-13 49.4 12.3 3e-07 30.5 1.4 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.65537.1_3 - 2.2e-05 24.5 0.9 2.2e-05 24.5 0.9 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.65537.1_3 - 7.8e-05 23.0 0.6 7.8e-05 23.0 0.6 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.65537.1_3 - 0.16 11.8 0.1 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger CP2 PF04516.13 MSTRG.124484.1_1 - 0.00046 19.5 0.0 0.00054 19.2 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor DUF2093 PF09866.7 MSTRG.124484.1_1 - 0.13 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) CP2 PF04516.13 MSTRG.124484.1_2 - 6.7e-18 64.7 0.0 7.2e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 CP2 transcription factor Sortilin-Vps10 PF15902.3 MSTRG.76419.1_1 - 2.5e-20 72.6 0.5 3.5e-20 72.1 0.5 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR_6 PF15899.3 MSTRG.76419.1_1 - 0.00046 19.9 2.6 0.075 13.0 0.2 3.1 3 0 0 3 3 3 2 BNR-Asp box repeat BNR PF02012.18 MSTRG.76419.1_1 - 0.0034 17.0 2.2 0.58 10.2 0.4 2.7 2 0 0 2 2 2 2 BNR/Asp-box repeat B_lectin PF01453.22 MSTRG.76419.1_1 - 0.093 12.6 0.6 15 5.5 0.0 2.6 1 1 1 2 2 2 0 D-mannose binding lectin DDE_3 PF13358.4 MSTRG.17786.1_3 - 1.1e-07 31.6 0.1 1.1e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1965 PF09248.8 MSTRG.121987.1_1 - 0.17 11.6 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) I-set PF07679.14 MSTRG.75945.1_1 - 5.4e-17 61.5 0.0 8e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.75945.1_1 - 1.6e-12 47.7 0.0 2.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.75945.1_1 - 1.8e-10 40.9 0.0 2.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.75945.1_1 - 1.1e-06 28.6 0.0 3.5e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 MSTRG.75945.1_1 - 2.4e-05 24.3 0.0 0.098 12.7 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.3 MSTRG.75945.1_1 - 0.0026 18.0 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Popeye PF04831.11 MSTRG.143099.2_3 - 3.1e-32 111.5 0.6 3.9e-32 111.2 0.6 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.27 MSTRG.143099.2_3 - 0.0028 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4070 PF13282.4 MSTRG.143099.2_3 - 0.043 13.8 0.3 0.07 13.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) POM121 PF15229.4 MSTRG.143099.2_3 - 0.095 12.3 4.4 0.14 11.8 4.4 1.1 1 0 0 1 1 1 0 POM121 family Integrin_beta PF00362.16 MSTRG.58070.1_2 - 3.1e-71 239.8 0.0 3.4e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Integrin beta chain VWA domain RRM_1 PF00076.20 MSTRG.38414.1_2 - 3.9e-08 32.9 0.0 8.4e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 MSTRG.38414.1_2 - 0.0024 17.8 0.1 0.019 14.9 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif Ribonuc_red_lgC PF02867.13 MSTRG.38414.1_2 - 0.044 12.2 0.0 0.055 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain Glyco_transf_49 PF13896.4 MSTRG.38414.1_2 - 0.12 11.6 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan DDE_Tnp_4 PF13359.4 MSTRG.300.1_2 - 3.2e-11 43.0 0.0 3.7e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PTEN_C2 PF10409.7 MSTRG.73328.1_3 - 1.1e-31 109.3 2.2 8.7e-31 106.3 2.2 1.9 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein SNF2_N PF00176.21 MSTRG.71966.1_3 - 1.6e-22 79.6 0.0 1.7e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.13 MSTRG.71966.1_3 - 0.043 13.7 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CLAMP PF14769.4 MSTRG.50278.1_2 - 0.0097 16.2 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Ank_5 PF13857.4 MSTRG.72481.1_3 - 1.1e-07 31.9 0.3 2.3e-07 30.8 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.4 MSTRG.72481.1_3 - 1.9e-05 24.5 0.1 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.4 MSTRG.72481.1_3 - 4.1e-05 23.9 0.1 0.0017 18.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 MSTRG.72481.1_3 - 0.00017 22.0 0.1 0.00022 21.6 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.28 MSTRG.72481.1_3 - 0.00095 19.4 0.5 0.025 14.9 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Podoplanin PF05808.9 MSTRG.6965.1_3 - 0.19 11.7 8.6 0.21 11.5 8.6 1.2 1 0 0 1 1 1 0 Podoplanin Med9 PF07544.11 MSTRG.20717.1_3 - 0.0012 18.7 2.4 0.0022 17.9 2.4 1.5 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 FliJ PF02050.14 MSTRG.20717.1_3 - 0.014 15.5 2.0 0.014 15.5 2.0 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein T7SS_ESX_EspC PF10824.6 MSTRG.20717.1_3 - 0.021 15.1 0.6 1.9 8.9 0.0 2.0 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm XhlA PF10779.7 MSTRG.20717.1_3 - 0.031 14.3 2.2 0.031 14.3 2.2 1.5 2 0 0 2 2 2 0 Haemolysin XhlA Cnn_1N PF07989.9 MSTRG.20717.1_3 - 0.064 13.3 4.0 0.097 12.7 4.0 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF342 PF03961.11 MSTRG.20717.1_3 - 0.11 10.9 3.8 0.12 10.8 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BST2 PF16716.3 MSTRG.20717.1_3 - 0.39 11.2 7.0 2.4 8.6 7.0 1.9 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 CENP-H PF05837.10 MSTRG.20717.1_3 - 0.51 10.6 6.0 1.5 9.1 6.0 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.10 MSTRG.20717.1_3 - 0.65 10.5 5.9 27 5.4 2.8 2.8 1 1 1 2 2 2 0 SlyX TolA_bind_tri PF16331.3 MSTRG.20717.1_3 - 1.6 8.7 9.0 19 5.3 0.4 2.8 1 1 1 2 2 2 0 TolA binding protein trimerisation bZIP_1 PF00170.19 MSTRG.20717.1_3 - 2 8.5 8.5 2.1 8.4 0.2 2.9 1 1 2 3 3 3 0 bZIP transcription factor RVT_1 PF00078.25 MSTRG.24593.1_3 - 3.6e-34 118.1 0.0 5.7e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANTH PF07651.14 MSTRG.32369.1_1 - 4.6e-22 78.2 0.3 5.8e-22 77.8 0.3 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.18 MSTRG.32369.1_1 - 1.2e-11 44.6 0.1 1.7e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 ENTH domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.8132.1_2 - 1.4e-14 53.9 0.2 1.6e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 Transposase Alk_phosphatase PF00245.18 MSTRG.128670.1_1 - 8.1e-07 28.2 0.0 9e-07 28.0 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.120243.1_1 - 2e-07 31.0 0.1 2.8e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Transposase Hydrolase PF00702.24 MSTRG.139821.1_3 - 3.7e-08 33.8 0.0 9.7e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.4 MSTRG.139821.1_3 - 9e-06 25.6 0.1 8.6e-05 22.4 0.0 2.5 2 1 1 3 3 3 1 Cation transport ATPase (P-type) TBCC PF07986.10 MSTRG.139821.1_3 - 0.019 14.6 1.4 0.036 13.6 1.4 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor C HAD PF12710.5 MSTRG.139821.1_3 - 0.056 13.7 0.1 0.57 10.4 0.1 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.10 MSTRG.139821.1_3 - 0.084 12.5 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase EGF_CA PF07645.13 MSTRG.120535.2_3 - 1e-85 281.6 172.1 1.4e-09 37.8 5.9 12.4 13 0 0 13 13 13 11 Calcium-binding EGF domain cEGF PF12662.5 MSTRG.120535.2_3 - 1.5e-69 229.3 90.6 2.3e-09 36.9 2.8 13.2 12 0 0 12 12 12 11 Complement Clr-like EGF-like FXa_inhibition PF14670.4 MSTRG.120535.2_3 - 2.1e-41 139.7 172.6 2.6e-09 37.1 10.3 12.1 12 0 0 12 12 12 11 Coagulation Factor Xa inhibitory site EGF PF00008.25 MSTRG.120535.2_3 - 5.7e-39 131.9 145.5 8.2e-05 22.7 6.5 12.9 12 1 1 13 13 13 11 EGF-like domain hEGF PF12661.5 MSTRG.120535.2_3 - 3.4e-21 75.0 162.6 0.00024 21.5 4.2 14.4 14 1 2 16 16 16 10 Human growth factor-like EGF EGF_3 PF12947.5 MSTRG.120535.2_3 - 5e-19 68.1 143.5 0.00081 19.4 6.7 12.6 12 0 0 12 12 12 11 EGF domain TB PF00683.15 MSTRG.120535.2_3 - 3.9e-18 64.7 21.4 8.5e-13 47.6 7.0 4.5 4 0 0 4 4 4 2 TB domain Plasmod_Pvs28 PF06247.9 MSTRG.120535.2_3 - 1.2e-14 54.1 119.8 0.0067 16.6 5.8 11.7 11 0 0 11 11 11 9 Pvs28 EGF domain T2SSM_b PF10741.7 MSTRG.28779.1_3 - 0.079 12.6 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Glyco_transf_90 PF05686.10 MSTRG.78054.1_1 - 1.7e-82 277.3 0.0 2.2e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.4 MSTRG.78054.1_1 - 0.00017 21.8 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 LIM PF00412.20 MSTRG.110715.1_1 - 6e-13 48.7 9.7 1.2e-12 47.7 9.7 1.5 1 0 0 1 1 1 1 LIM domain Yae1_N PF09811.7 MSTRG.1064.1_3 - 1.1e-08 34.5 4.3 1.4e-08 34.1 4.3 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal COX7a PF02238.13 MSTRG.137872.2_1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII F-box-like PF12937.5 MSTRG.87579.1_1 - 1.7e-13 50.1 0.5 2e-13 49.8 0.5 1.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 MSTRG.87579.1_1 - 4.1e-11 42.3 1.1 5.6e-11 41.9 1.1 1.3 1 0 0 1 1 1 1 F-box domain MOR2-PAG1_N PF14222.4 MSTRG.138928.1_1 - 3.4e-31 108.7 0.1 3.7e-31 108.6 0.1 1.0 1 0 0 1 1 1 1 Cell morphogenesis N-terminal DUF1943 PF09172.9 MSTRG.50012.1_1 - 0.0049 16.1 0.1 0.0054 15.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) DUF1439 PF07273.10 MSTRG.50012.1_1 - 0.094 12.4 0.3 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) DUF2490 PF10677.7 MSTRG.50012.1_1 - 0.22 11.3 10.3 0.41 10.4 10.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2490) Transglut_N PF00868.18 MSTRG.28420.1_1 - 1e-30 106.4 0.0 1.5e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase family BicD PF09730.7 MSTRG.9157.1_3 - 2e-16 59.5 0.2 2.2e-16 59.4 0.2 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Death PF00531.20 MSTRG.59601.1_1 - 3.7e-19 68.5 0.1 4.7e-19 68.2 0.1 1.2 1 0 0 1 1 1 1 Death domain Exo_endo_phos_2 PF14529.4 MSTRG.39371.1_3 - 2e-05 24.3 0.0 0.076 12.7 0.0 2.1 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.21 MSTRG.39371.1_3 - 0.014 15.5 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family MIP-T3 PF10243.7 MSTRG.105219.1_1 - 0.69 8.4 35.3 0.82 8.2 35.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Raftlin PF15250.4 MSTRG.105219.1_1 - 8.4 4.9 13.4 9.7 4.7 13.4 1.2 1 0 0 1 1 1 0 Raftlin SRP-alpha_N PF04086.11 MSTRG.105219.1_1 - 9.9 5.8 28.1 13 5.5 28.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BC10 PF06726.10 MSTRG.120272.1_2 - 0.015 15.4 0.8 0.017 15.2 0.8 1.2 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 EF-hand_8 PF13833.4 MSTRG.13958.1_1 - 0.00013 21.5 0.1 0.00021 20.8 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.4 MSTRG.13958.1_1 - 0.0018 18.6 0.1 0.0031 17.8 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair NMT_C PF02799.13 MSTRG.13958.1_1 - 0.019 14.4 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain EF-hand_6 PF13405.4 MSTRG.13958.1_1 - 0.029 14.1 0.2 1.9 8.5 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain ThiI PF02568.12 MSTRG.13958.1_1 - 0.05 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) SPARC_Ca_bdg PF10591.7 MSTRG.13958.1_1 - 0.073 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Levi_coat PF01819.15 MSTRG.13958.1_1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Levivirus coat protein Lip_A_acyltrans PF03279.11 MSTRG.13958.1_1 - 0.21 10.6 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Peptidase_M1 PF01433.18 MSTRG.49006.1_2 - 1e-65 222.4 1.0 1.2e-65 222.1 1.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 DUF2363 PF10155.7 MSTRG.2513.1_1 - 1.8e-05 24.8 0.1 2.2e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) EB1 PF03271.15 MSTRG.78972.1_3 - 2.4e-15 56.3 0.1 6.3e-15 55.0 0.1 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.29 MSTRG.78972.1_3 - 1.3e-11 44.5 0.3 2e-11 43.9 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.6 MSTRG.78972.1_3 - 0.0011 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain zf-C3HC4 PF00097.23 MSTRG.27853.1_2 - 0.036 13.8 4.2 0.064 13.0 4.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.4 MSTRG.28574.1_2 - 6.2e-22 77.5 1.0 1.2e-11 44.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 MSTRG.28574.1_2 - 4.2e-13 49.6 0.5 8.6e-13 48.6 0.5 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.28 MSTRG.28574.1_2 - 4.6e-13 48.8 0.5 0.00052 20.2 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.4 MSTRG.28574.1_2 - 1.1e-12 46.8 0.2 0.00055 20.1 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.4 MSTRG.28574.1_2 - 4.6e-12 45.8 1.7 1.7e-05 24.9 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Nop14 PF04147.10 MSTRG.50649.1_2 - 5.7 4.9 17.3 6 4.8 17.3 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.12 MSTRG.50649.1_2 - 7.4 4.6 11.5 9.8 4.2 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.9 MSTRG.50649.1_2 - 9.1 6.2 14.6 7.3 6.5 10.4 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal PPP4R2 PF09184.9 MSTRG.50649.1_2 - 9.2 5.6 27.4 17 4.7 27.2 1.6 1 1 1 2 2 2 0 PPP4R2 CD36 PF01130.19 MSTRG.43594.1_3 - 6.1e-39 133.7 0.7 7.1e-39 133.5 0.7 1.0 1 0 0 1 1 1 1 CD36 family RRM_1 PF00076.20 MSTRG.38982.1_1 - 4.7e-16 58.2 0.0 5.9e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 MSTRG.38982.1_1 - 0.00015 21.6 0.0 0.00034 20.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif I-set PF07679.14 MSTRG.36811.1_3 - 0.00039 20.3 0.0 0.00049 20.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.15 MSTRG.36811.1_3 - 0.028 14.4 0.1 1.3 9.1 0.1 2.1 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ig_3 PF13927.4 MSTRG.36811.1_3 - 0.04 14.4 0.0 0.062 13.8 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Integrase_Zn PF02022.17 MSTRG.60764.1_1 - 0.29 11.0 4.4 2.2 8.1 0.3 3.3 4 0 0 4 4 4 0 Integrase Zinc binding domain HECT PF00632.23 MSTRG.72903.1_2 - 1.1e-19 70.9 0.0 1.2e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NADHdh_A3 PF14987.4 MSTRG.20372.1_1 - 1e-37 128.2 0.8 1.2e-37 128.0 0.8 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 MFS_1 PF07690.14 MSTRG.43623.3_1 - 9.9e-09 34.4 9.6 5.2e-08 32.1 1.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 MSTRG.43623.3_1 - 0.011 14.5 0.0 0.011 14.5 0.0 1.5 2 0 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.14 MSTRG.43623.3_2 - 4.1e-23 81.7 18.1 6.1e-23 81.2 18.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3649 PF12365.6 MSTRG.127109.1_1 - 0.15 11.7 1.8 37 4.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3649) Cadherin_3 PF16184.3 MSTRG.30671.1_2 - 1.6e-10 40.9 0.0 1.7e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Cadherin-like WD40 PF00400.30 MSTRG.34231.1_2 - 3e-15 56.2 3.9 4e-08 33.7 1.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat FYVE PF01363.19 MSTRG.34231.1_2 - 3.5e-10 39.7 4.5 6.9e-10 38.8 4.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger ANAPC4_WD40 PF12894.5 MSTRG.34231.1_2 - 1.4e-05 25.2 0.0 0.024 14.8 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.9 MSTRG.34231.1_2 - 0.032 12.9 0.0 1 7.9 0.0 1.8 1 1 1 2 2 2 0 Nup133 N terminal like ELYS-bb PF16687.3 MSTRG.34231.1_2 - 0.059 11.9 0.0 0.12 10.9 0.0 1.4 1 1 0 1 1 1 0 beta-propeller of ELYS nucleoporin zf-B_box PF00643.22 MSTRG.34231.1_2 - 0.063 13.3 1.3 0.063 13.3 1.3 2.5 2 0 0 2 2 2 0 B-box zinc finger IBR PF01485.19 MSTRG.34231.1_2 - 1.2 9.2 13.0 34 4.6 13.0 2.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain PPDFL PF15060.4 MSTRG.7568.1_2 - 5.5e-48 162.0 1.6 9e-48 161.3 1.6 1.3 1 0 0 1 1 1 1 Differentiation and proliferation regulator Ribosomal_L18A PF01775.15 MSTRG.97302.1_2 - 0.087 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A OST3_OST6 PF04756.11 MSTRG.97302.1_3 - 5.2e-09 35.7 1.2 6.8e-09 35.4 1.2 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TRAP_alpha PF03896.14 MSTRG.50397.1_1 - 1e-90 303.7 0.0 1.2e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit NINJA_B PF16136.3 MSTRG.75493.1_2 - 0.014 15.6 2.4 0.02 15.1 2.4 1.2 1 0 0 1 1 1 0 Putative nuclear localisation signal DUF2514 PF10721.7 MSTRG.75493.1_2 - 0.31 10.9 4.7 0.51 10.2 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) HLH PF00010.24 MSTRG.66263.1_3 - 3.3e-17 62.0 0.2 5.8e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mto2_bdg PF12808.5 MSTRG.66263.1_3 - 0.0051 17.0 1.1 0.0051 17.0 1.1 2.1 3 0 0 3 3 3 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Enolase_C PF00113.20 MSTRG.65105.1_1 - 5.9e-85 284.9 0.0 7e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.4 MSTRG.65105.1_1 - 1.7e-09 37.5 0.0 2.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.9 MSTRG.65105.1_1 - 4.2e-06 26.0 0.3 0.00012 21.1 0.4 2.1 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Metallothio_Pro PF02069.14 MSTRG.136055.1_2 - 0.059 13.5 4.8 3.8 7.7 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic metallothionein PHBC_N PF12551.6 MSTRG.143540.1_3 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal WWE PF02825.18 MSTRG.93638.1_2 - 7.2e-16 58.4 0.8 1.1e-15 57.7 0.8 1.3 1 0 0 1 1 1 1 WWE domain Neuralized PF07177.10 MSTRG.17974.1_2 - 2.1e-18 66.7 0.0 2.3e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Neuralized DUF2608 PF11019.6 MSTRG.17974.1_2 - 0.11 11.8 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Nebulin PF00880.16 MSTRG.92115.1_3 - 5.3e-12 45.3 0.0 3.4e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Nebulin repeat Metallophos PF00149.26 MSTRG.123434.1_1 - 2.9e-25 89.8 0.0 3.3e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.3 MSTRG.123434.1_1 - 8.4e-11 42.0 0.8 1.5e-10 41.2 0.8 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Histone PF00125.22 MSTRG.34188.1_1 - 1.1e-09 38.6 0.0 1.5e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RhoGEF PF00621.18 MSTRG.34188.1_1 - 7.5e-07 29.4 0.6 1.7e-06 28.3 0.6 1.5 1 0 0 1 1 1 1 RhoGEF domain Mis14 PF08641.10 MSTRG.68988.1_2 - 1.8e-15 57.3 6.2 3.4e-15 56.4 2.6 2.4 1 1 1 2 2 2 1 Kinetochore protein Mis14 like DUF932 PF06067.9 MSTRG.68988.1_2 - 0.11 12.2 3.4 0.2 11.3 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF932) DUF948 PF06103.9 MSTRG.64969.1_2 - 0.0062 16.6 2.0 0.0088 16.2 2.0 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) YscO PF07321.10 MSTRG.64969.1_2 - 0.021 14.7 11.7 0.024 14.4 11.7 1.0 1 0 0 1 1 1 0 Type III secretion protein YscO Dna2 PF08696.9 MSTRG.64969.1_2 - 0.026 14.2 1.4 0.029 14.0 1.4 1.0 1 0 0 1 1 1 0 DNA replication factor Dna2 HOOK PF05622.10 MSTRG.64969.1_2 - 0.045 11.8 11.4 0.053 11.5 11.4 1.0 1 0 0 1 1 1 0 HOOK protein AAA_13 PF13166.4 MSTRG.64969.1_2 - 0.069 11.7 6.2 0.076 11.5 6.2 1.0 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.18 MSTRG.64969.1_2 - 0.079 12.8 12.4 0.76 9.6 2.3 2.0 1 1 1 2 2 2 0 Prefoldin subunit FimP PF09766.7 MSTRG.64969.1_2 - 0.08 12.1 9.2 0.086 12.0 9.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein BLOC1_2 PF10046.7 MSTRG.64969.1_2 - 0.085 13.1 7.1 1.2 9.4 7.3 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.11 MSTRG.64969.1_2 - 0.086 13.1 4.9 0.12 12.7 3.2 1.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Fib_alpha PF08702.8 MSTRG.64969.1_2 - 0.094 12.8 6.6 0.12 12.4 6.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.10 MSTRG.64969.1_2 - 0.1 12.9 3.3 0.44 10.9 1.8 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.7 MSTRG.64969.1_2 - 0.14 11.1 10.5 0.17 10.8 10.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.7 MSTRG.64969.1_2 - 0.15 10.8 10.2 0.16 10.6 10.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.9 MSTRG.64969.1_2 - 0.2 10.4 10.6 0.21 10.3 10.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Dam1 PF08653.8 MSTRG.64969.1_2 - 0.26 11.0 2.0 1.1 8.9 0.4 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF2937 PF11157.6 MSTRG.64969.1_2 - 0.28 10.7 2.4 0.3 10.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF641 PF04859.10 MSTRG.64969.1_2 - 0.34 11.1 6.9 0.44 10.7 6.9 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.17 MSTRG.64969.1_2 - 0.4 8.4 8.2 0.44 8.3 8.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family dCache_2 PF08269.9 MSTRG.64969.1_2 - 0.43 9.6 7.0 0.45 9.5 7.0 1.0 1 0 0 1 1 1 0 Cache domain TMPIT PF07851.11 MSTRG.64969.1_2 - 0.48 9.5 6.2 0.51 9.4 6.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.10 MSTRG.64969.1_2 - 0.53 10.1 5.2 0.71 9.7 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2203 PF09969.7 MSTRG.64969.1_2 - 0.69 10.5 5.7 0.83 10.3 5.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.9 MSTRG.64969.1_2 - 0.7 10.2 6.7 2.1 8.6 6.7 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) BST2 PF16716.3 MSTRG.64969.1_2 - 0.71 10.3 10.6 1.2 9.6 10.6 1.4 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 APG6 PF04111.10 MSTRG.64969.1_2 - 0.74 9.0 10.6 0.77 9.0 10.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 XhlA PF10779.7 MSTRG.64969.1_2 - 0.81 9.8 10.3 4.3 7.5 10.1 1.9 1 1 0 1 1 1 0 Haemolysin XhlA Prefoldin PF02996.15 MSTRG.64969.1_2 - 0.99 9.2 9.8 1.7 8.5 6.0 2.1 1 1 2 3 3 3 0 Prefoldin subunit IncA PF04156.12 MSTRG.64969.1_2 - 1.2 8.8 11.0 1.6 8.3 11.0 1.2 1 0 0 1 1 1 0 IncA protein DUF4094 PF13334.4 MSTRG.64969.1_2 - 1.3 9.3 6.0 2.1 8.7 6.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Exonuc_VII_L PF02601.13 MSTRG.64969.1_2 - 2.1 7.7 7.6 2.1 7.7 7.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.11 MSTRG.64969.1_2 - 4.1 5.8 9.0 4.2 5.7 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UCH PF00443.27 MSTRG.44490.1_3 - 4.1e-17 62.4 0.0 4.1e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 MSTRG.44490.1_3 - 0.00012 21.7 0.0 0.00014 21.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C6H2 PF15801.3 MSTRG.44490.1_3 - 0.16 12.2 0.7 0.89 9.8 0.1 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Ribosomal_S30 PF04758.12 MSTRG.68263.1_1 - 1.1e-30 105.4 11.4 1.6e-30 104.9 11.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.21 MSTRG.68263.1_1 - 9.9e-14 50.7 0.1 1.5e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family RHD_dimer PF16179.3 MSTRG.136529.2_1 - 5.1e-09 36.0 0.0 5.8e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Rel homology dimerisation domain FeoB_C PF07664.10 MSTRG.136529.2_1 - 0.0043 16.6 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B C terminus Ion_trans PF00520.29 MSTRG.6876.1_3 - 4.2e-06 26.1 1.8 4.8e-06 25.8 1.8 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.10 MSTRG.6876.1_3 - 0.029 12.9 0.8 0.035 12.6 0.8 1.1 1 0 0 1 1 1 0 Polycystin cation channel GPHH PF16905.3 MSTRG.6876.1_3 - 0.13 12.0 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated C_tripleX PF02363.17 MSTRG.110992.1_1 - 0.027 14.6 14.2 2.4e+03 -0.9 14.2 3.4 1 1 0 1 1 1 0 Cysteine rich repeat C_tripleX PF02363.17 MSTRG.110992.1_2 - 1.1 9.6 16.8 2 8.8 0.9 3.6 3 1 0 3 3 3 0 Cysteine rich repeat C_tripleX PF02363.17 MSTRG.110992.1_3 - 0.11 12.7 17.3 1.6e+04 -4.2 17.3 3.4 1 1 0 1 1 1 0 Cysteine rich repeat DUF2407 PF10302.7 MSTRG.22212.1_1 - 0.091 13.2 1.5 0.13 12.7 1.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain HECT PF00632.23 MSTRG.84785.4_3 - 2.9e-90 302.7 1.0 5.3e-90 301.9 0.3 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.16 MSTRG.84785.4_3 - 5.1e-85 279.8 26.3 1.4e-15 57.5 0.0 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 MSTRG.84785.4_3 - 8.9e-43 143.1 33.6 3.3e-09 36.2 0.1 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat DDE_3 PF13358.4 MSTRG.51030.1_1 - 1.4e-05 24.7 0.1 1.6e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.16 MSTRG.130252.1_2 - 1.8e-15 56.8 2.7 2.3e-15 56.5 1.4 1.7 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.4 MSTRG.130252.1_2 - 0.0019 18.6 0.1 0.0029 18.0 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain V-set PF07686.15 MSTRG.55213.1_2 - 4e-11 42.9 0.0 4.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 MSTRG.55213.1_2 - 0.00014 21.8 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 MSTRG.55213.1_2 - 0.0034 17.8 0.0 0.0068 16.9 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 MSTRG.55213.1_2 - 0.037 14.0 0.0 0.079 12.9 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin I-set domain zf-C2H2_jaz PF12171.6 MSTRG.18347.1_1 - 0.13 12.5 0.2 0.13 12.5 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4407 PF14362.4 MSTRG.113336.1_2 - 0.0023 17.2 0.1 0.0024 17.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Yuri_gagarin PF15934.3 MSTRG.113336.1_2 - 0.076 12.7 5.0 0.099 12.3 5.0 1.1 1 0 0 1 1 1 0 Yuri gagarin CHD5 PF04420.12 MSTRG.113336.1_2 - 0.4 10.4 4.5 0.37 10.5 3.4 1.5 1 1 0 1 1 1 0 CHD5-like protein DivIC PF04977.13 MSTRG.113336.1_2 - 0.9 9.2 5.9 0.43 10.3 2.2 2.0 1 1 1 2 2 2 0 Septum formation initiator Bap31 PF05529.10 MSTRG.113336.1_2 - 1.5 8.3 5.5 1.9 7.9 5.5 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like HTH_Tnp_Tc3_2 PF01498.16 MSTRG.91017.1_2 - 0.043 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Transposase RVT_1 PF00078.25 MSTRG.63335.1_2 - 0.0086 15.5 0.0 0.0095 15.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PP1_inhibitor PF05361.10 MSTRG.95272.1_1 - 0.018 14.9 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor 3HCDH_N PF02737.16 MSTRG.113702.1_2 - 3.6e-53 180.0 1.0 1.4e-52 178.1 0.9 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.18 MSTRG.113702.1_2 - 1.2e-40 139.3 1.0 1.9e-40 138.6 1.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.20 MSTRG.113702.1_2 - 5.2e-32 110.2 0.0 3.6e-25 88.3 0.1 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.3 MSTRG.113702.1_2 - 2.9e-27 95.9 0.1 5.7e-27 95.0 0.1 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase fn3 PF00041.19 MSTRG.18630.1_2 - 4.1e-07 30.1 0.2 0.00012 22.3 0.0 3.0 3 0 0 3 3 3 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.3 MSTRG.18630.1_2 - 0.00019 21.8 0.0 0.0016 18.9 0.0 2.2 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain MOZART1 PF12554.6 MSTRG.94425.1_2 - 0.014 15.0 0.1 0.039 13.6 0.1 1.7 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF3433 PF11915.6 MSTRG.101313.1_3 - 0.092 13.1 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) PA PF02225.20 MSTRG.38854.1_1 - 4.5e-05 23.3 0.0 6.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 PA domain WW PF00397.24 MSTRG.124595.3_3 - 0.0002 21.1 0.4 0.00037 20.2 0.4 1.5 1 0 0 1 1 1 1 WW domain zf-RING_7 PF02591.13 MSTRG.124595.3_3 - 0.086 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain FCH PF00611.21 MSTRG.108763.2_3 - 4.7e-18 65.1 2.0 4.7e-18 65.1 2.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain MAP65_ASE1 PF03999.10 MSTRG.108763.2_3 - 0.0017 17.0 2.9 0.0021 16.7 2.9 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF2683 PF10884.6 MSTRG.108763.2_3 - 0.14 12.4 2.2 0.3 11.2 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) Carbpep_Y_N PF05388.9 MSTRG.108763.2_3 - 0.26 11.7 2.3 4.6 7.6 0.2 2.4 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Med21 PF11221.6 MSTRG.108763.2_3 - 0.37 10.9 3.8 3.1 7.9 0.7 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex LMP PF04778.10 MSTRG.108763.2_3 - 0.54 10.0 6.2 2.2 8.0 0.1 2.1 1 1 1 2 2 2 0 LMP repeated region DUF4795 PF16043.3 MSTRG.108763.2_3 - 0.8 9.1 6.1 3.8 6.9 5.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Defensin_big PF14862.4 MSTRG.60186.1_3 - 0.036 14.2 1.9 0.046 13.9 1.9 1.2 1 0 0 1 1 1 0 Big defensin PRA1 PF03208.17 MSTRG.10752.1_1 - 3.9e-40 136.6 3.2 5.2e-40 136.2 3.2 1.1 1 0 0 1 1 1 1 PRA1 family protein DNAP_B_exo_N PF08452.8 MSTRG.37819.1_2 - 0.06 12.6 0.1 0.15 11.3 0.1 1.7 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal FH2 PF02181.21 MSTRG.38828.1_3 - 5.1e-20 71.8 0.1 5.5e-20 71.7 0.1 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain COMMD1_N PF17221.1 MSTRG.38828.1_3 - 0.042 14.0 0.1 0.051 13.7 0.1 1.1 1 0 0 1 1 1 0 COMMD1 N-terminal domain BAR_3_WASP_bdg PF10456.7 MSTRG.38828.1_3 - 0.092 12.1 0.1 1.3 8.3 0.0 1.9 1 1 1 2 2 2 0 WASP-binding domain of Sorting nexin protein 2C_adapt PF08793.8 MSTRG.41138.1_2 - 0.013 15.5 3.0 2.4 8.3 0.1 3.0 3 0 0 3 3 3 0 2-cysteine adaptor domain COX4 PF02936.12 MSTRG.41138.1_2 - 0.074 12.9 0.4 2.8 7.8 0.0 2.7 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Nnf1 PF03980.12 MSTRG.41138.1_3 - 0.23 11.7 0.4 22 5.3 0.0 2.4 1 1 2 3 3 3 0 Nnf1 zf-Tim10_DDP PF02953.13 MSTRG.41138.1_3 - 0.26 10.9 3.8 7.5 6.2 0.2 2.7 1 1 2 3 3 3 0 Tim10/DDP family zinc finger Gelsolin PF00626.20 MSTRG.94354.1_3 - 9.5e-10 38.1 0.0 1.1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Gelsolin repeat SNF2_N PF00176.21 MSTRG.130313.1_3 - 2.7e-18 65.7 0.2 3e-18 65.5 0.2 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Hormone_recep PF00104.28 MSTRG.30291.1_3 - 1.7e-12 47.2 0.2 3.9e-12 46.1 0.1 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RVT PF13966.4 MSTRG.2446.1_1 - 8.3e-05 23.2 0.0 0.00012 22.7 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase EGF_CA PF07645.13 MSTRG.109477.1_1 - 3.6e-21 75.0 24.0 5.7e-12 45.5 4.9 3.0 3 0 0 3 3 3 2 Calcium-binding EGF domain cEGF PF12662.5 MSTRG.109477.1_1 - 3.6e-13 49.0 6.4 4.7e-10 39.1 0.4 4.0 4 1 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.5 MSTRG.109477.1_1 - 5.1e-05 23.3 18.9 0.011 15.8 2.5 3.4 3 0 0 3 3 3 2 EGF domain FXa_inhibition PF14670.4 MSTRG.109477.1_1 - 0.00027 21.0 19.4 0.0016 18.6 0.6 3.9 2 1 1 3 3 3 2 Coagulation Factor Xa inhibitory site EGF PF00008.25 MSTRG.109477.1_1 - 10 6.4 24.4 2.1 8.6 5.3 4.6 3 2 0 3 3 3 0 EGF-like domain Pur_ac_phosph_N PF16656.3 MSTRG.119225.1_1 - 0.084 13.3 0.0 0.13 12.7 0.0 1.3 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain SlyX PF04102.10 MSTRG.81366.2_2 - 0.0041 17.6 0.1 0.0088 16.5 0.1 1.6 1 0 0 1 1 1 1 SlyX Glyco_hydro_38C PF07748.11 MSTRG.31956.1_3 - 2.4e-10 39.9 0.1 3e-10 39.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain GldM_N PF12081.6 MSTRG.30770.1_1 - 0.093 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain Op_neuropeptide PF08035.9 MSTRG.30770.1_2 - 0.19 11.5 0.5 0.19 11.5 0.5 2.1 2 0 0 2 2 2 0 Opioids neuropeptide Clathrin-link PF09268.8 MSTRG.20249.1_2 - 0.17 11.2 1.5 0.31 10.3 1.5 1.4 1 0 0 1 1 1 0 Clathrin, heavy-chain linker RVT_1 PF00078.25 MSTRG.79892.1_2 - 0.00035 20.0 0.0 0.00044 19.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) fn3 PF00041.19 MSTRG.62142.1_1 - 7.2e-06 26.1 0.1 9.3e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Fibronectin type III domain HGAL PF15666.3 MSTRG.120157.1_1 - 0.0056 16.6 0.2 3.6 7.6 0.0 2.1 2 0 0 2 2 2 2 Germinal center-associated lymphoma HGAL PF15666.3 MSTRG.120157.1_2 - 0.0057 16.6 0.3 3.3 7.7 0.1 2.1 2 0 0 2 2 2 2 Germinal center-associated lymphoma PRA1 PF03208.17 MSTRG.17380.2_1 - 4.5e-34 117.0 0.1 7e-34 116.4 0.1 1.3 1 0 0 1 1 1 1 PRA1 family protein VERL PF11386.6 MSTRG.30648.1_2 - 0.091 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin DUF3808 PF10300.7 MSTRG.28044.1_1 - 2.9e-21 75.6 0.0 3.1e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) MNHE PF01899.14 MSTRG.13229.1_1 - 0.0059 16.2 0.1 28 4.3 0.0 4.0 1 1 3 4 4 4 3 Na+/H+ ion antiporter subunit DUF137 PF02006.14 MSTRG.13229.1_1 - 0.27 10.6 1.2 74 2.7 0.1 3.7 1 1 3 4 4 4 0 Protein of unknown function DUF137 adh_short PF00106.23 MSTRG.13229.1_2 - 3e-05 23.4 0.1 4.1e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DENN PF02141.19 MSTRG.4668.1_2 - 8e-07 29.0 0.0 8.5e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 DENN (AEX-3) domain ubiquitin PF00240.21 MSTRG.130666.2_1 - 0.012 15.1 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family DUF1240 PF06836.10 MSTRG.130666.2_1 - 0.037 14.4 0.7 0.12 12.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Myosin_TH1 PF06017.11 MSTRG.13303.1_3 - 1.2e-51 174.9 0.5 1.4e-51 174.6 0.5 1.0 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding PI3_PI4_kinase PF00454.25 MSTRG.15661.1_2 - 1.2e-35 123.4 0.0 1.3e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.4 MSTRG.15661.1_2 - 0.00057 19.2 0.0 0.00057 19.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Ribosomal_S5 PF00333.18 MSTRG.36067.1_2 - 0.067 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain tRNA-synt_1 PF00133.20 MSTRG.109565.1_3 - 0.22 9.6 0.1 0.25 9.4 0.1 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) RNA_pol_Rpb2_1 PF04563.13 MSTRG.4427.1_2 - 0.018 14.4 0.1 0.025 14.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase beta subunit MSG PF02349.13 MSTRG.110620.1_2 - 0.072 13.2 0.7 0.58 10.3 0.7 2.0 1 1 0 1 1 1 0 Major surface glycoprotein Chitin_bind_1 PF00187.17 MSTRG.110620.1_2 - 8.8 6.8 19.5 1.6e+04 -8.5 19.5 3.9 1 1 0 1 1 1 0 Chitin recognition protein DUF3105 PF11303.6 MSTRG.58738.1_1 - 1.5e-20 73.5 0.1 1.9e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) Thioredoxin PF00085.18 MSTRG.32005.1_3 - 5.9e-92 302.4 0.6 3.5e-31 107.1 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.4 MSTRG.32005.1_3 - 1.9e-25 89.8 8.5 1.6e-18 67.2 2.0 4.3 4 0 0 4 4 4 4 Thioredoxin-like domain OST3_OST6 PF04756.11 MSTRG.32005.1_3 - 4.6e-16 58.9 0.1 0.00016 21.0 0.0 3.3 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 MSTRG.32005.1_3 - 2.1e-14 53.7 2.2 0.0024 18.2 0.1 4.2 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.4 MSTRG.32005.1_3 - 5.7e-14 52.1 0.9 0.01 16.0 0.0 6.0 4 2 2 6 6 6 3 Thioredoxin-like Thioredoxin_7 PF13899.4 MSTRG.32005.1_3 - 2e-13 50.2 0.0 0.0017 18.4 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin-like Calsequestrin PF01216.15 MSTRG.32005.1_3 - 3.1e-10 39.5 1.5 3.3e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 Calsequestrin AhpC-TSA PF00578.19 MSTRG.32005.1_3 - 5.6e-09 35.8 0.1 0.28 11.0 0.0 3.5 3 0 0 3 3 3 3 AhpC/TSA family Thioredoxin_4 PF13462.4 MSTRG.32005.1_3 - 1.1e-06 28.8 1.7 1 9.4 0.0 4.2 3 0 0 3 3 3 3 Thioredoxin Redoxin PF08534.8 MSTRG.32005.1_3 - 1e-05 25.1 0.9 1.2 8.6 0.0 4.2 5 0 0 5 5 5 2 Redoxin HyaE PF07449.9 MSTRG.32005.1_3 - 0.0014 18.5 0.1 2.3 8.1 0.0 4.1 6 0 0 6 6 6 1 Hydrogenase-1 expression protein HyaE DSBA PF01323.18 MSTRG.32005.1_3 - 0.032 13.9 3.2 19 4.8 0.2 4.4 3 2 2 5 5 5 0 DSBA-like thioredoxin domain NUC194 PF08163.10 MSTRG.80217.1_1 - 0.17 10.9 7.9 0.24 10.4 7.9 1.2 1 0 0 1 1 1 0 NUC194 domain eIF-3_zeta PF05091.10 MSTRG.80217.1_1 - 0.38 9.5 9.4 0.4 9.5 9.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Exonuc_VII_L PF02601.13 MSTRG.80217.1_1 - 0.49 9.8 13.1 0.57 9.6 13.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Neur_chan_memb PF02932.14 MSTRG.80217.1_1 - 3.5 7.5 8.2 3.8 7.4 8.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.7 MSTRG.80217.1_1 - 3.7 5.6 27.5 3.9 5.5 27.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3797 PF12677.5 MSTRG.80217.1_2 - 0.13 12.1 0.4 0.21 11.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) PH PF00169.27 MSTRG.29305.1_2 - 3e-19 69.4 0.1 5.9e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 MSTRG.29305.1_2 - 8e-09 35.7 2.9 3.8e-06 27.1 0.8 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.4 MSTRG.29305.1_2 - 6.1e-06 26.2 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.4 MSTRG.29305.1_2 - 0.00035 20.6 0.0 0.00035 20.6 0.0 2.1 3 0 0 3 3 3 1 Pleckstrin homology domain PH_2 PF08458.8 MSTRG.29305.1_2 - 0.00051 20.2 0.3 0.0034 17.6 0.3 2.2 1 1 0 1 1 1 1 Plant pleckstrin homology-like region PH_13 PF16652.3 MSTRG.29305.1_2 - 0.035 13.8 0.2 0.064 13.0 0.2 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Bac_small_YrzI PF09501.8 MSTRG.88062.2_1 - 0.41 10.7 5.1 2.7 8.1 1.3 2.3 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) EMP70 PF02990.14 MSTRG.88062.2_3 - 1.7e-12 46.7 0.1 2.1e-12 46.4 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Globin PF00042.20 MSTRG.133272.1_1 - 3.1e-10 40.5 0.0 4.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Globin Globin PF00042.20 MSTRG.133272.1_3 - 1.2e-07 32.1 0.1 3.7e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Globin DDE_3 PF13358.4 MSTRG.230.1_3 - 9.6e-12 44.7 0.0 1.1e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_8 PF13181.4 MSTRG.100481.1_1 - 3.3e-11 42.3 2.0 0.0034 17.3 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.4 MSTRG.100481.1_1 - 5e-11 42.3 0.8 0.099 13.4 0.0 5.1 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_12 PF13424.4 MSTRG.100481.1_1 - 2.2e-10 40.5 0.1 2.7e-05 24.2 0.0 2.9 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_2 PF07719.15 MSTRG.100481.1_1 - 2.7e-10 39.4 4.8 0.00018 21.2 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.4 MSTRG.100481.1_1 - 3.5e-06 27.3 0.0 0.2 12.1 0.0 4.0 4 1 0 5 5 3 1 Tetratricopeptide repeat TPR_16 PF13432.4 MSTRG.100481.1_1 - 6e-06 26.7 0.6 0.21 12.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.10 MSTRG.100481.1_1 - 2.2e-05 24.3 1.3 0.83 9.5 0.0 4.1 3 1 0 4 4 4 2 Mad3/BUB1 homology region 1 TPR_15 PF13429.4 MSTRG.100481.1_1 - 3e-05 23.2 0.4 0.0084 15.2 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.4 MSTRG.100481.1_1 - 4.6e-05 22.8 0.8 0.04 13.2 0.0 3.1 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.4 MSTRG.100481.1_1 - 5.1e-05 22.9 1.5 0.013 15.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.4 MSTRG.100481.1_1 - 0.0001 22.3 0.1 27 5.3 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.26 MSTRG.100481.1_1 - 0.00026 20.5 3.5 0.05 13.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.4 MSTRG.100481.1_1 - 0.0031 17.2 0.9 5.1 7.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.5 MSTRG.100481.1_1 - 0.0033 17.5 0.0 8.9 6.5 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Nic96 PF04097.12 MSTRG.100481.1_1 - 0.0082 14.5 0.1 0.15 10.4 0.0 2.1 2 0 0 2 2 2 1 Nup93/Nic96 PPR PF01535.18 MSTRG.100481.1_1 - 0.0096 16.0 0.2 0.4 10.9 0.0 3.2 3 0 0 3 3 3 1 PPR repeat RPN7 PF10602.7 MSTRG.100481.1_1 - 0.019 14.5 0.2 2.4 7.6 0.0 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.4 MSTRG.100481.1_1 - 0.037 14.5 5.3 42 4.9 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.7 MSTRG.100481.1_1 - 0.076 12.6 0.2 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.12 MSTRG.100481.1_1 - 0.099 13.2 0.0 4.8 8.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.4 MSTRG.100481.1_1 - 1.2 8.7 5.8 11 5.7 0.1 3.4 4 0 0 4 4 3 0 TPR repeat GAIN PF16489.3 MSTRG.98067.1_1 - 1.4e-39 135.6 2.9 1.8e-39 135.2 2.9 1.2 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain GPS PF01825.19 MSTRG.98067.1_1 - 2.6e-13 50.2 6.4 6.6e-13 48.9 6.4 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif 7tm_2 PF00002.22 MSTRG.98067.1_1 - 1.8e-12 46.9 5.7 3.3e-12 46.1 5.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF2371 PF10177.7 MSTRG.98067.1_1 - 0.068 13.2 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Phage_int_SAM_1 PF02899.15 MSTRG.98067.1_1 - 0.24 11.6 1.3 2.6 8.3 0.1 2.4 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Sema PF01403.17 MSTRG.134783.1_2 - 0.0005 18.8 0.1 0.0005 18.8 0.1 1.0 1 0 0 1 1 1 1 Sema domain ubiquitin PF00240.21 MSTRG.113587.1_3 - 3e-08 33.1 0.0 5.2e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.7 MSTRG.113587.1_3 - 0.01 16.3 0.0 0.014 15.8 0.0 1.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Glyco_hydro_56 PF01630.16 MSTRG.6476.1_1 - 1e-119 399.4 0.0 1.1e-119 399.2 0.0 1.0 1 0 0 1 1 1 1 Hyaluronidase KAP PF05804.10 MSTRG.24776.1_3 - 2.4e-55 187.9 0.1 2.6e-55 187.7 0.1 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) zf-C2H2 PF00096.24 MSTRG.132452.1_3 - 6e-18 64.1 30.4 4.6e-07 29.8 3.7 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.132452.1_3 - 2.4e-17 62.4 33.3 3.1e-09 36.7 1.5 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.132452.1_3 - 1.8e-12 46.8 20.9 0.00049 20.6 0.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.3 MSTRG.132452.1_3 - 6.3e-06 25.7 17.8 0.0017 18.0 0.4 3.5 3 0 0 3 3 3 3 zinc-finger C2H2-type zf-met PF12874.5 MSTRG.132452.1_3 - 1.4e-05 25.2 16.1 0.0084 16.3 0.9 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type GAGA PF09237.9 MSTRG.132452.1_3 - 0.00051 19.7 4.7 0.13 11.9 0.8 2.5 2 0 0 2 2 2 2 GAGA factor zf-C2HE PF16278.3 MSTRG.132452.1_3 - 0.0045 17.3 14.5 0.36 11.2 1.2 3.9 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.3 MSTRG.132452.1_3 - 0.011 16.3 8.0 0.086 13.5 3.8 3.2 3 0 0 3 3 3 0 zinc-ribbon family zf-C2H2_jaz PF12171.6 MSTRG.132452.1_3 - 0.014 15.6 7.8 0.11 12.7 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.4 MSTRG.132452.1_3 - 0.015 14.9 0.9 0.015 14.9 0.9 3.8 4 0 0 4 4 3 0 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.3 MSTRG.132452.1_3 - 0.49 10.2 5.2 1.3 8.8 3.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.8 MSTRG.132452.1_3 - 4.7 7.3 11.4 0.13 12.3 0.8 2.8 1 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.5 MSTRG.132452.1_3 - 5.4 7.3 13.5 3.4 7.9 2.5 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) UIM PF02809.18 MSTRG.38020.2_2 - 0.00055 19.5 4.2 0.00055 19.5 4.2 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-AN1 PF01428.14 MSTRG.38020.2_3 - 3.3e-20 71.8 34.2 7.4e-11 41.9 11.2 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.13 MSTRG.38020.2_3 - 0.052 13.8 18.5 0.11 12.7 6.0 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C5HC2 PF02928.14 MSTRG.38020.2_3 - 1.4 9.2 21.9 1.9 8.8 2.4 4.6 4 0 0 4 4 4 0 C5HC2 zinc finger His_Phos_1 PF00300.20 MSTRG.69765.1_3 - 8.5e-11 41.8 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3696 PF12476.6 MSTRG.110681.1_2 - 6.7 7.0 12.1 45 4.4 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3696) PUF PF00806.17 MSTRG.110681.1_3 - 0.0073 15.8 0.5 87 3.0 0.0 4.0 1 1 3 4 4 4 0 Pumilio-family RNA binding repeat DUF3953 PF13129.4 MSTRG.110681.1_3 - 0.029 14.0 0.4 12 5.6 0.0 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3953) Gas_vesicle_C PF01304.15 MSTRG.110681.1_3 - 0.042 13.7 4.3 74 3.3 0.0 4.0 4 0 0 4 4 4 0 Gas vesicles protein GVPc repeated domain PX PF00787.22 MSTRG.100244.1_2 - 1.4e-14 53.9 0.4 1.5e-14 53.8 0.4 1.1 1 0 0 1 1 1 1 PX domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.34228.1_3 - 5.2e-17 61.7 0.1 8.4e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 Transposase DUF2917 PF11142.6 MSTRG.4572.1_1 - 0.16 11.3 2.2 6.4 6.1 2.2 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2917) LCE PF14672.4 MSTRG.4572.1_1 - 0.4 11.2 5.8 0.71 10.4 5.8 1.4 1 0 0 1 1 1 0 Late cornified envelope HTH_Tnp_Tc3_2 PF01498.16 MSTRG.114204.1_1 - 4.7e-22 77.9 0.8 1.1e-21 76.6 0.8 1.7 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.4 MSTRG.114204.1_1 - 0.00011 21.8 0.7 0.00056 19.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.114204.1_1 - 0.0055 16.3 0.1 0.05 13.3 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.114204.1_1 - 0.029 14.8 0.8 0.41 11.2 0.0 2.7 1 1 2 3 3 3 0 Homeodomain-like domain PAX PF00292.16 MSTRG.114204.1_1 - 0.039 13.7 0.1 0.065 13.0 0.1 1.4 1 1 0 1 1 1 0 'Paired box' domain DDE_3 PF13358.4 MSTRG.139385.1_1 - 2.6e-07 30.4 0.2 3.4e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Ski_Sno PF02437.15 MSTRG.123272.2_1 - 1.9e-42 143.3 0.2 4e-42 142.3 0.2 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.8 MSTRG.123272.2_1 - 4.6e-38 129.2 1.3 1e-37 128.1 1.3 1.6 1 0 0 1 1 1 1 c-SKI Smad4 binding domain I_LWEQ PF01608.15 MSTRG.57161.1_3 - 2.9e-47 160.6 6.8 3.2e-47 160.5 6.8 1.0 1 0 0 1 1 1 1 I/LWEQ domain NRBF2_MIT PF17169.2 MSTRG.57161.1_3 - 0.043 13.9 0.5 0.11 12.6 0.4 1.7 1 1 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 DUF4261 PF14080.4 MSTRG.57161.1_3 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) Tower PF09121.8 MSTRG.110136.1_2 - 1.4 9.0 10.7 28 4.9 0.3 3.9 1 1 3 4 4 4 0 Tower Arc PF03869.12 MSTRG.110136.1_2 - 4.6 7.0 4.9 94 2.8 0.0 3.2 4 0 0 4 4 4 0 Arc-like DNA binding domain PAH PF02671.19 MSTRG.110136.1_3 - 0.012 15.6 0.5 76 3.4 0.0 3.9 4 0 0 4 4 4 0 Paired amphipathic helix repeat RRM_1 PF00076.20 MSTRG.116904.1_1 - 1e-17 63.5 0.0 1.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.9 MSTRG.116904.1_1 - 0.0059 16.5 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.6 MSTRG.116904.1_1 - 0.051 13.5 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 HTH_28 PF13518.4 MSTRG.40524.1_1 - 0.055 13.5 0.4 0.068 13.2 0.4 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.4 MSTRG.40524.1_1 - 0.15 11.7 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.40524.1_2 - 2.1e-10 40.6 0.6 2.8e-10 40.2 0.6 1.2 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.4 MSTRG.40524.1_2 - 0.00043 20.7 2.6 0.00052 20.5 2.6 1.1 1 0 0 1 1 1 1 Homeodomain-like domain Gp49 PF05973.12 MSTRG.94013.1_2 - 0.039 14.0 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) DUF1031 PF06275.9 MSTRG.5526.1_3 - 0.0099 16.0 0.2 0.013 15.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1031) C1-set PF07654.13 MSTRG.5526.1_3 - 0.043 14.1 0.1 0.059 13.7 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin C1-set domain FixQ PF05545.9 MSTRG.77591.1_3 - 0.051 13.4 1.3 0.13 12.2 1.3 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ HTH_Tnp_Tc3_2 PF01498.16 MSTRG.33730.1_1 - 8.5e-13 48.2 0.4 2.1e-12 47.0 0.4 1.7 1 0 0 1 1 1 1 Transposase PAX PF00292.16 MSTRG.33730.1_3 - 0.0027 17.5 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.4 MSTRG.33730.1_3 - 0.007 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Peptidase_M14 PF00246.22 MSTRG.74211.1_3 - 1.4e-10 41.3 0.0 1.5e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase ANF_receptor PF01094.26 MSTRG.139178.1_1 - 7.2e-08 31.8 0.5 7.7e-08 31.7 0.5 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region HTH_Tnp_Tc3_2 PF01498.16 MSTRG.19644.1_2 - 0.11 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Transposase DUF202 PF02656.13 MSTRG.70148.1_3 - 0.12 12.7 0.8 0.12 12.7 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Antistasin PF02822.12 MSTRG.66027.1_3 - 1.4e-10 41.4 23.2 3.7e-06 27.3 10.8 4.1 4 1 0 4 4 4 2 Antistasin family VWC PF00093.16 MSTRG.66027.1_3 - 1.2e-06 28.6 5.2 1.2e-06 28.6 5.2 3.1 1 1 1 2 2 2 1 von Willebrand factor type C domain Clat_adaptor_s PF01217.18 MSTRG.126359.1_2 - 0.00033 20.5 0.1 0.00053 19.8 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sigma_reg_N PF13800.4 MSTRG.19252.1_2 - 0.077 13.2 0.3 0.1 12.7 0.3 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DDE_3 PF13358.4 MSTRG.97900.1_1 - 9.2e-05 22.1 0.0 0.00029 20.5 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease Hormone_recep PF00104.28 MSTRG.85940.1_3 - 9.8e-14 51.3 0.0 1.1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MTBP_C PF14920.4 MSTRG.12831.1_3 - 0.15 11.6 0.0 0.17 11.5 0.0 1.0 1 0 0 1 1 1 0 MDM2-binding DUF1891 PF09004.8 MSTRG.91030.1_2 - 3.5e-09 36.0 0.9 8.2e-09 34.8 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) RVT_1 PF00078.25 MSTRG.91030.1_2 - 0.00041 19.8 0.1 0.0033 16.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dynein_IC2 PF11540.6 MSTRG.65884.1_2 - 5.1e-14 51.8 0.1 9.5e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 RR_TM4-6 PF06459.10 MSTRG.65884.1_2 - 0.081 12.6 8.2 0.097 12.3 8.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_BLLF1 PF05109.11 MSTRG.65884.1_2 - 0.11 10.4 1.7 0.12 10.2 1.7 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF913 PF06025.10 MSTRG.65884.1_2 - 0.15 10.9 2.7 0.16 10.8 2.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Cellulose_synt PF03552.12 MSTRG.65884.1_2 - 0.97 7.7 2.1 1.2 7.4 2.1 1.0 1 0 0 1 1 1 0 Cellulose synthase Presenilin PF01080.15 MSTRG.65884.1_2 - 1.1 7.7 5.3 1.2 7.7 5.3 1.1 1 0 0 1 1 1 0 Presenilin Astro_capsid_p PF12226.6 MSTRG.65884.1_2 - 1.5 7.8 11.0 2 7.4 11.0 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF3306 PF11748.6 MSTRG.65884.1_2 - 1.9 9.3 10.0 0.49 11.1 7.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) THOC2_N PF16134.3 MSTRG.65884.1_2 - 8.9 4.7 8.1 12 4.3 8.1 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus UQ_con PF00179.24 MSTRG.14118.1_2 - 1.6e-14 53.6 0.4 1.7e-14 53.5 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bromodomain PF00439.23 MSTRG.3293.1_2 - 3.8e-09 36.4 0.0 3.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Bromodomain CNDH2_N PF06278.9 MSTRG.128897.1_3 - 2e-13 50.4 0.0 2.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal V-set PF07686.15 MSTRG.54169.1_1 - 0.00016 21.6 0.0 0.00018 21.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain RPA_interact_C PF14768.4 MSTRG.103139.1_2 - 5.7e-13 49.1 2.6 5.7e-13 49.1 2.6 2.0 2 0 0 2 2 2 1 Replication protein A interacting C-terminal RPA_interact_M PF14767.4 MSTRG.103139.1_3 - 1.5e-21 76.6 7.6 2.2e-21 76.1 7.6 1.2 1 0 0 1 1 1 1 Replication protein A interacting middle RPA_interact_N PF14766.4 MSTRG.103139.1_3 - 2.3e-17 62.3 5.4 5.7e-17 61.0 5.4 1.7 1 0 0 1 1 1 1 Replication protein A interacting N-terminal DUF4693 PF15764.3 MSTRG.103139.1_3 - 0.06 12.8 0.2 0.09 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4693) Cadherin_2 PF08266.10 MSTRG.17913.1_2 - 0.17 11.6 0.2 5.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Cadherin-like DUF3449 PF11931.6 MSTRG.3993.1_3 - 9.3e-78 260.1 3.0 9.3e-78 260.1 3.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.4 MSTRG.3993.1_3 - 9.7e-30 101.9 1.3 2.2e-29 100.8 1.3 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.3 MSTRG.3993.1_3 - 8e-24 83.8 6.8 2.6e-23 82.2 6.8 2.0 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.6 MSTRG.3993.1_3 - 1.1e-15 57.0 1.2 2.5e-15 55.9 1.2 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain DUF3772 PF12607.6 MSTRG.3993.1_3 - 0.063 12.9 0.4 0.15 11.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Diphthamide_syn PF01866.15 MSTRG.107926.1_3 - 5.8e-29 101.3 0.5 6.2e-29 101.2 0.5 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ogr_Delta PF04606.10 MSTRG.73279.1_2 - 0.022 14.6 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger DUF1430 PF07242.9 MSTRG.83871.1_2 - 0.5 10.5 0.1 0.5 10.5 0.1 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1430) Peptidase_M41 PF01434.16 MSTRG.118030.2_2 - 5.2e-77 258.1 0.2 7.6e-77 257.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.27 MSTRG.118030.2_2 - 4.4e-43 146.7 0.0 7.8e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 MSTRG.118030.2_2 - 0.00082 19.5 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.12 MSTRG.118030.2_2 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 MSTRG.118030.2_2 - 0.0014 18.5 0.0 0.0042 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.11 MSTRG.118030.2_2 - 0.0062 15.4 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.4 MSTRG.118030.2_2 - 0.0075 16.5 0.2 0.14 12.4 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.10 MSTRG.118030.2_2 - 0.0097 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.15 MSTRG.118030.2_2 - 0.043 13.4 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein I-set PF07679.14 MSTRG.130746.1_3 - 9.9e-20 70.3 0.0 1.1e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.130746.1_3 - 4.6e-11 43.1 0.0 4.9e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Receptor_2B4 PF11465.6 MSTRG.130746.1_3 - 6.8e-05 22.9 0.0 8.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 Ig_2 PF13895.4 MSTRG.130746.1_3 - 0.00024 21.2 0.0 0.00026 21.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.130746.1_3 - 0.0031 17.5 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 MSTRG.130746.1_3 - 0.028 14.5 0.0 0.076 13.1 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin V-set domain Spt20 PF12090.6 MSTRG.81373.1_2 - 0.52 9.7 6.3 0.56 9.6 6.3 1.1 1 0 0 1 1 1 0 Spt20 family Apt1 PF10351.7 MSTRG.81373.1_2 - 5.7 5.5 10.1 6.7 5.3 10.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1151 PF06625.9 MSTRG.102374.1_2 - 1.1e-42 144.5 20.7 1.5e-42 144.0 20.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) ubiquitin PF00240.21 MSTRG.77621.1_3 - 1.9e-05 24.2 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 MSTRG.77621.1_3 - 0.041 13.6 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like C_tripleX PF02363.17 MSTRG.85305.1_1 - 0.25 11.5 9.3 2.9e+02 2.0 9.3 3.0 1 1 0 1 1 1 0 Cysteine rich repeat Ribosomal_S19e PF01090.17 MSTRG.99924.1_1 - 1e-54 183.8 0.1 1.3e-54 183.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e COX8 PF02285.13 MSTRG.97348.1_1 - 0.12 12.1 14.4 24 4.8 0.1 5.0 4 1 1 5 5 5 0 Cytochrome oxidase c subunit VIII CpcD PF01383.19 MSTRG.97348.1_2 - 0.002 18.2 0.7 6.7 6.9 0.1 3.2 2 1 1 3 3 3 3 CpcD/allophycocyanin linker domain Forkhead PF00250.16 MSTRG.53760.1_2 - 1.7e-19 69.8 0.4 2.1e-19 69.5 0.4 1.1 1 0 0 1 1 1 1 Forkhead domain Erv26 PF04148.11 MSTRG.92185.1_2 - 9.3e-11 41.8 5.6 1.1e-10 41.5 5.6 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 RhoGEF PF00621.18 MSTRG.122597.1_3 - 7.1e-20 71.9 0.3 1.2e-19 71.2 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain Baculo_11_kDa PF06143.9 MSTRG.100074.1_3 - 0.96 8.9 7.2 1.6 8.2 7.2 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Asp_protease PF09668.8 MSTRG.133078.1_3 - 0.043 13.5 0.1 0.058 13.1 0.1 1.1 1 0 0 1 1 1 0 Aspartyl protease PDZ PF00595.22 MSTRG.120887.1_3 - 1.3e-06 28.6 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DDE_3 PF13358.4 MSTRG.50967.1_1 - 1.2e-12 47.6 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.4 MSTRG.102916.1_3 - 1.2e-13 51.0 0.5 1.2e-13 51.0 0.5 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.24 MSTRG.102916.1_3 - 0.017 15.1 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain RRM_1 PF00076.20 MSTRG.117721.1_1 - 1.5e-18 66.3 0.1 4.8e-18 64.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rep_fac-A_C PF08646.8 MSTRG.25292.1_2 - 3.6e-47 159.6 8.5 4.8e-45 152.8 6.0 2.7 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.3 MSTRG.25292.1_2 - 5.7e-35 119.0 0.3 6.8e-34 115.6 0.1 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.10 MSTRG.25292.1_2 - 1.3e-24 86.0 0.0 2.5e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.23 MSTRG.25292.1_2 - 2.2e-11 43.5 0.3 4e-10 39.4 0.1 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Pox_vIL-18BP PF05566.10 MSTRG.25292.1_2 - 0.082 13.0 0.5 1.1 9.3 0.2 2.5 2 1 0 2 2 2 0 Orthopoxvirus interleukin 18 binding protein Mucin-like PF16058.3 MSTRG.25292.1_2 - 0.13 12.3 2.8 0.22 11.5 2.8 1.3 1 0 0 1 1 1 0 Mucin-like IBR PF01485.19 MSTRG.25292.1_2 - 0.31 11.2 6.9 0.55 10.4 6.0 1.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain PPR_2 PF13041.4 MSTRG.57695.1_3 - 0.034 14.2 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family PPR PF01535.18 MSTRG.57695.1_3 - 0.065 13.4 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 PPR repeat COPIIcoated_ERV PF07970.10 MSTRG.15886.1_2 - 1.6e-31 109.8 0.3 2e-31 109.4 0.3 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter DOCK_N PF16172.3 MSTRG.33737.1_2 - 0.00029 19.7 0.0 0.00037 19.4 0.0 1.1 1 0 0 1 1 1 1 DOCK N-terminus HeH PF12949.5 MSTRG.21557.1_2 - 0.11 12.1 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 HeH/LEM domain DUF4764 PF15961.3 MSTRG.28327.1_1 - 1.6e-53 182.5 3.2 2.5e-53 181.8 3.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4764) Cytadhesin_P30 PF07271.9 MSTRG.28327.1_1 - 0.056 12.9 5.3 0.024 14.1 2.5 1.7 2 0 0 2 2 2 0 Cytadhesin P30/P32 Ran_BP1 PF00638.16 MSTRG.100924.1_3 - 2.8e-14 53.3 0.0 5.2e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF4566 PF15130.4 MSTRG.133221.1_2 - 2.5e-50 170.9 1.0 4e-50 170.2 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) F-box-like PF12937.5 MSTRG.11760.3_1 - 1.4e-15 56.8 0.4 2.4e-15 56.0 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 MSTRG.11760.3_1 - 7.5e-08 31.9 0.3 1.1e-07 31.4 0.3 1.3 1 0 0 1 1 1 1 F-box domain MEF2_binding PF09047.8 MSTRG.59565.1_3 - 0.047 13.4 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 MEF2 binding DSPc PF00782.18 MSTRG.105897.1_3 - 2e-31 108.4 0.0 2.6e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Biotin_lipoyl PF00364.20 MSTRG.71424.1_1 - 2.8e-13 49.4 0.1 4.3e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme 2-oxoacid_dh PF00198.21 MSTRG.71424.1_1 - 8.4e-08 31.8 1.3 1.1e-07 31.4 1.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl_2 PF13533.4 MSTRG.71424.1_1 - 3.5e-06 26.6 0.4 6.2e-06 25.8 0.4 1.4 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_D23 PF16576.3 MSTRG.71424.1_1 - 0.0064 15.6 0.1 0.0098 15.0 0.1 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Carb_kinase PF01256.15 MSTRG.110272.1_3 - 1.7e-16 60.3 0.0 1.7e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.10 MSTRG.110272.1_3 - 0.014 14.7 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase uDENN PF03456.16 MSTRG.47656.1_1 - 0.014 16.0 1.2 0.032 14.9 1.2 1.6 1 1 0 1 1 1 0 uDENN domain TraW_N PF12477.6 MSTRG.91701.1_2 - 1.5 8.7 5.9 0.14 12.0 1.2 1.7 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal SRCR PF00530.16 MSTRG.10454.1_3 - 1.1e-28 99.5 1.5 1.8e-28 98.9 1.5 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.4 MSTRG.10454.1_3 - 0.00028 21.2 0.1 0.00056 20.2 0.1 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain ATP-gua_PtransN PF02807.13 MSTRG.132706.1_3 - 1.8e-25 89.0 0.0 2.6e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain NAD_binding_10 PF13460.4 MSTRG.25103.1_1 - 3.3e-06 27.0 0.0 3.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Aldedh PF00171.20 MSTRG.142610.1_2 - 2.3e-09 36.2 0.4 1.1e-08 33.9 0.1 2.1 2 1 0 2 2 2 1 Aldehyde dehydrogenase family HEAT PF02985.20 MSTRG.102801.2_1 - 2.5e-14 52.0 0.7 0.00045 20.1 0.0 3.9 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.4 MSTRG.102801.2_1 - 6.9e-06 26.2 0.0 2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 HEAT repeats Vac14_Fab1_bd PF12755.5 MSTRG.102801.2_1 - 1.4e-05 25.5 0.1 6.6e-05 23.3 0.1 2.0 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.5 MSTRG.102801.2_1 - 0.0088 15.9 0.3 0.013 15.4 0.3 1.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.4 MSTRG.102801.2_2 - 3.5e-05 24.0 0.1 5.1e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.20 MSTRG.102801.2_2 - 0.02 14.9 0.3 0.1 12.8 0.0 2.2 3 0 0 3 3 3 0 HEAT repeat DDE_3 PF13358.4 MSTRG.54359.1_3 - 3.2e-11 43.0 0.0 3.8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-PARP PF00645.16 MSTRG.39125.1_1 - 5.2e-25 88.0 1.0 1e-24 87.1 1.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF3377 PF11857.6 MSTRG.128647.1_3 - 4.8 7.1 7.2 2.5 8.0 5.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) TMEM154 PF15102.4 MSTRG.128647.1_3 - 7.2 6.4 6.0 9.6 6.0 6.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Defensin_2 PF01097.16 MSTRG.37949.1_3 - 0.063 13.1 1.5 0.097 12.5 1.5 1.3 1 0 0 1 1 1 0 Arthropod defensin IRS PF02174.15 MSTRG.49160.1_2 - 4.8e-32 109.7 0.0 7.7e-32 109.0 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.27 MSTRG.49160.1_2 - 4.8e-09 36.5 0.9 8.9e-09 35.7 0.9 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 MSTRG.49160.1_2 - 0.00014 22.1 1.7 0.00041 20.6 1.7 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.4 MSTRG.49160.1_2 - 0.0019 18.3 0.1 0.0041 17.2 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain ubiquitin PF00240.21 MSTRG.130533.1_3 - 0.00066 19.2 0.0 0.00088 18.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DAGAT PF03982.11 MSTRG.58665.1_2 - 3.3e-39 134.4 0.0 4.1e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase RVT_1 PF00078.25 MSTRG.113261.1_1 - 9.5e-22 77.5 0.1 1.3e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 MSTRG.113261.1_2 - 4.1e-06 26.3 0.0 5.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4 PF00097.23 MSTRG.55675.1_3 - 1.6e-08 34.1 7.5 3.3e-08 33.1 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 MSTRG.55675.1_3 - 2.3e-05 24.0 4.2 2.3e-05 24.0 4.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 MSTRG.55675.1_3 - 3.2e-05 23.6 4.9 3.2e-05 23.6 4.9 1.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.4 MSTRG.55675.1_3 - 3.8e-05 23.6 9.3 3.8e-05 23.6 9.3 1.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.4 MSTRG.55675.1_3 - 0.00027 20.6 8.8 0.00027 20.6 8.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 MSTRG.55675.1_3 - 0.00031 20.6 6.0 0.00031 20.6 6.0 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 MSTRG.55675.1_3 - 0.00059 19.6 7.6 0.0014 18.5 7.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.4 MSTRG.55675.1_3 - 0.0019 18.3 8.0 0.0019 18.3 8.0 1.8 2 0 0 2 2 2 1 Ring finger domain DZR PF12773.5 MSTRG.55675.1_3 - 0.23 11.4 6.0 0.71 9.8 6.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon ODC_AZ PF02100.15 MSTRG.139410.1_2 - 3.9e-21 75.1 0.0 6.3e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme MLANA PF14991.4 MSTRG.139410.1_3 - 0.066 13.4 0.2 4.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein melan-A zf-CCHC PF00098.21 MSTRG.103548.1_2 - 0.01 15.8 0.6 0.01 15.8 0.6 2.2 2 0 0 2 2 2 1 Zinc knuckle Myb_DNA-bind_4 PF13837.4 MSTRG.77642.1_2 - 4.5e-16 58.9 0.1 5.8e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2437 PF10370.7 MSTRG.70027.1_1 - 0.074 13.9 0.0 0.096 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) Antimicrobial14 PF08109.9 MSTRG.68468.1_1 - 0.011 15.6 14.4 2.1 8.3 0.2 3.7 4 0 0 4 4 4 0 Lactocin 705 family DUF4400 PF14348.4 MSTRG.21053.1_2 - 2.6 7.3 4.1 3.6 6.9 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) BID PF06393.9 MSTRG.107085.1_2 - 1.8e-12 47.0 0.0 2.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 BH3 interacting domain (BID) G-gamma PF00631.20 MSTRG.52325.1_1 - 0.041 13.7 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 GGL domain Ribosomal_L35p PF01632.17 MSTRG.64224.1_3 - 2e-14 53.7 9.1 3.2e-14 53.0 9.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 IL33 PF15095.4 MSTRG.64224.1_3 - 0.11 11.8 1.8 0.16 11.2 1.8 1.2 1 0 0 1 1 1 0 Interleukin 33 RVT_1 PF00078.25 MSTRG.70112.1_2 - 7.9e-08 31.9 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1891 PF09004.8 MSTRG.70112.1_3 - 4.2e-07 29.3 0.1 8.6e-07 28.3 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1891) HR1 PF02185.14 MSTRG.106515.1_2 - 2e-51 171.8 21.1 1.1e-17 63.8 4.2 3.3 3 0 0 3 3 3 3 Hr1 repeat Uds1 PF15456.4 MSTRG.106515.1_2 - 2.8e-06 27.4 17.1 0.0076 16.3 1.8 3.3 2 1 1 3 3 3 3 Up-regulated During Septation REC114-like PF15165.4 MSTRG.106515.1_2 - 0.00027 20.6 4.2 0.0004 20.1 4.2 1.3 1 0 0 1 1 1 1 Meiotic recombination protein REC114-like DUF2489 PF10675.7 MSTRG.106515.1_2 - 0.0014 18.4 11.8 0.92 9.3 0.1 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF2489) PL48 PF15903.3 MSTRG.106515.1_2 - 0.28 10.0 4.9 0.37 9.6 0.4 2.6 2 1 0 3 3 3 0 Filopodia upregulated, FAM65 Flagellin_N PF00669.18 MSTRG.106515.1_2 - 1.6 8.7 10.1 0.055 13.4 2.0 2.4 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region Fib_alpha PF08702.8 MSTRG.106515.1_2 - 4 7.5 11.9 8 6.5 0.9 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family W2 PF02020.16 MSTRG.112389.1_2 - 5.2e-21 74.4 3.8 7.9e-21 73.9 3.8 1.3 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon ATXN-1_C PF12547.6 MSTRG.3565.1_3 - 9.1 6.6 8.7 28 5.0 0.0 2.2 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator WD40 PF00400.30 MSTRG.46629.1_1 - 1.9e-20 72.7 6.6 0.0008 20.0 0.0 6.0 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.46629.1_1 - 1.8e-05 24.8 0.0 0.043 14.0 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 MSTRG.46629.1_1 - 3.8e-05 23.5 0.2 0.013 15.2 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A EGF_2 PF07974.11 MSTRG.7272.2_1 - 0.18 12.1 2.5 0.33 11.2 2.5 1.4 1 0 0 1 1 1 0 EGF-like domain Topoisom_I_N PF02919.13 MSTRG.7272.2_3 - 0.028 13.8 0.6 0.028 13.8 0.6 2.0 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Presenilin PF01080.15 MSTRG.7272.2_3 - 2.2 6.8 7.7 3.2 6.3 7.7 1.2 1 0 0 1 1 1 0 Presenilin Glyco_tran_10_N PF17039.3 MSTRG.118368.2_1 - 6.4e-34 116.6 0.0 1.3e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.17 MSTRG.118368.2_1 - 2.5e-07 30.4 0.0 3.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term ACP_syn_III PF08545.8 MSTRG.119764.1_1 - 0.07 12.9 0.1 0.087 12.6 0.1 1.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Fer4_4 PF12800.5 MSTRG.121901.1_1 - 5.9 7.5 7.9 2.5 8.7 3.3 2.4 2 1 0 2 2 2 0 4Fe-4S binding domain MARCKS PF02063.15 MSTRG.20715.1_3 - 6.5e-12 45.9 70.5 7.5e-11 42.4 70.5 2.1 1 1 0 1 1 1 1 MARCKS family DUF1681 PF07933.12 MSTRG.36014.1_2 - 3.3e-54 182.5 0.0 3.7e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DnaJ PF00226.29 MSTRG.106450.1_2 - 2.6e-15 56.2 0.6 6.1e-15 55.0 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain AAA_23 PF13476.4 MSTRG.106450.1_2 - 4.6 7.6 13.7 6.9 7.0 13.7 1.3 1 0 0 1 1 1 0 AAA domain CbtA PF09490.8 MSTRG.138975.1_1 - 0.1 12.2 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Laminin_B PF00052.16 MSTRG.46203.1_3 - 2.1e-26 92.2 0.0 2.9e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_EGF PF00053.22 MSTRG.46203.1_3 - 3.1e-25 87.9 84.5 2.9e-09 36.8 15.5 5.2 5 1 0 5 5 5 4 Laminin EGF domain DUF641 PF04859.10 MSTRG.77144.1_3 - 3.3e-05 24.1 0.9 4.5e-05 23.7 0.9 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) ADIP PF11559.6 MSTRG.77144.1_3 - 0.00055 19.9 1.8 0.00075 19.5 1.8 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CEP63 PF17045.3 MSTRG.77144.1_3 - 0.0027 17.5 0.3 0.0032 17.3 0.3 1.1 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa HIP1_clath_bdg PF16515.3 MSTRG.77144.1_3 - 0.0051 17.3 0.8 0.0063 17.0 0.8 1.1 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 LRRFIP PF09738.7 MSTRG.77144.1_3 - 0.012 15.0 2.5 0.012 15.0 2.5 1.4 1 1 1 2 2 2 0 LRRFIP family TolA_bind_tri PF16331.3 MSTRG.77144.1_3 - 0.013 15.4 0.7 0.022 14.7 0.7 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation IncA PF04156.12 MSTRG.77144.1_3 - 0.029 14.0 0.2 0.029 14.0 0.2 1.1 1 0 0 1 1 1 0 IncA protein Fez1 PF06818.13 MSTRG.77144.1_3 - 0.049 13.9 1.3 0.051 13.9 1.3 1.0 1 0 0 1 1 1 0 Fez1 IBN_N PF03810.17 MSTRG.125303.1_2 - 3.4e-18 65.2 0.5 3.1e-17 62.1 0.0 2.0 1 1 1 2 2 2 1 Importin-beta N-terminal domain DEK_C PF08766.9 MSTRG.125303.1_2 - 0.15 11.9 0.2 0.29 11.0 0.0 1.5 2 0 0 2 2 2 0 DEK C terminal domain FANCI_S1-cap PF14674.4 MSTRG.125303.1_2 - 0.37 10.8 1.9 0.5 10.4 0.7 1.9 2 0 0 2 2 2 0 FANCI solenoid 1 cap I-set PF07679.14 MSTRG.44028.1_3 - 1.1e-09 38.0 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.44028.1_3 - 0.00012 22.4 0.0 0.00021 21.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.44028.1_3 - 0.0053 16.8 0.1 0.0086 16.1 0.0 1.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.44028.1_3 - 0.017 15.3 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain CGI-121 PF08617.8 MSTRG.52770.1_1 - 2.6e-07 30.8 0.0 3.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 RVT_1 PF00078.25 MSTRG.134197.1_2 - 5e-09 35.9 0.0 5.8e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.4 MSTRG.98774.1_2 - 2.8e-13 49.7 0.1 3.8e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.16 MSTRG.98774.1_2 - 9.8e-07 28.8 0.2 1.7e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 Transposase DUF1018 PF06252.10 MSTRG.98774.1_2 - 0.099 13.6 0.1 0.72 10.8 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) MHC_I_3 PF16497.3 MSTRG.139440.1_3 - 0.078 12.3 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 MHC-I family domain RGP PF03214.11 MSTRG.139440.1_3 - 0.13 11.3 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide Integrase_Zn PF02022.17 MSTRG.93211.1_1 - 3.8 7.4 6.2 5.7 6.8 0.1 3.5 2 1 3 5 5 5 0 Integrase Zinc binding domain RRM_1 PF00076.20 MSTRG.133863.1_2 - 0.00038 20.1 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 MSTRG.133863.1_2 - 0.00056 19.4 0.0 0.031 13.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.7 MSTRG.11310.1_2 - 0.036 13.2 2.2 0.041 13.0 2.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CENP-F_leu_zip PF10473.7 MSTRG.11310.1_2 - 0.038 13.9 1.7 0.038 13.9 1.7 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.10 MSTRG.11310.1_2 - 0.047 13.0 1.5 1.7 7.8 0.2 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein KASH_CCD PF14662.4 MSTRG.11310.1_2 - 0.054 13.2 20.4 0.55 9.9 11.6 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH KfrA_N PF11740.6 MSTRG.11310.1_2 - 0.074 13.6 13.9 1.4 9.5 1.9 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term TPR_MLP1_2 PF07926.10 MSTRG.11310.1_2 - 0.078 12.9 19.5 0.15 12.0 5.5 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RmuC PF02646.14 MSTRG.11310.1_2 - 0.11 11.5 11.9 0.077 12.0 3.0 2.1 2 0 0 2 2 2 0 RmuC family Rootletin PF15035.4 MSTRG.11310.1_2 - 0.12 12.3 15.6 0.18 11.7 15.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion BLOC1_2 PF10046.7 MSTRG.11310.1_2 - 0.21 11.8 13.2 0.058 13.6 2.8 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.19 MSTRG.11310.1_2 - 0.31 11.0 0.2 0.31 11.0 0.2 3.3 2 1 1 3 3 3 0 bZIP transcription factor PMC2NT PF08066.10 MSTRG.11310.1_2 - 0.54 10.8 8.9 6.7 7.3 3.0 2.7 1 1 0 2 2 2 0 PMC2NT (NUC016) domain XhlA PF10779.7 MSTRG.11310.1_2 - 0.58 10.3 4.7 1.2 9.3 0.6 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Mnd1 PF03962.13 MSTRG.11310.1_2 - 0.59 9.8 14.7 1.5 8.5 14.5 1.7 1 1 0 1 1 1 0 Mnd1 family FTA4 PF13093.4 MSTRG.11310.1_2 - 0.59 9.9 10.9 0.056 13.2 4.4 1.9 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Muted PF14942.4 MSTRG.11310.1_2 - 0.61 10.3 18.2 2.7 8.2 4.4 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4600 PF15372.4 MSTRG.11310.1_2 - 0.65 10.3 14.0 3.8 7.8 2.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) DUF972 PF06156.11 MSTRG.11310.1_2 - 0.69 10.4 14.3 1.2 9.6 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-C4pol PF14260.4 MSTRG.11310.1_2 - 1 9.7 4.0 0.51 10.7 0.6 2.2 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF4200 PF13863.4 MSTRG.11310.1_2 - 1.1 9.5 20.2 0.17 12.1 3.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Jnk-SapK_ap_N PF09744.7 MSTRG.11310.1_2 - 1.4 9.0 19.7 0.11 12.6 2.6 2.5 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 NPV_P10 PF05531.10 MSTRG.11310.1_2 - 1.8 9.0 10.7 3 8.2 1.5 2.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.6 MSTRG.11310.1_2 - 1.9 8.4 16.6 0.59 10.1 5.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding eIF3_N PF09440.8 MSTRG.11310.1_2 - 2.3 8.5 13.0 0.62 10.4 5.4 2.2 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain IncA PF04156.12 MSTRG.11310.1_2 - 2.4 7.8 25.2 6.1 6.5 21.8 2.1 1 1 1 2 2 2 0 IncA protein Ax_dynein_light PF10211.7 MSTRG.11310.1_2 - 3.1 7.5 16.3 0.2 11.5 2.0 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain ALMT PF11744.6 MSTRG.11310.1_2 - 3.6 6.2 8.0 4.4 5.9 8.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Spc7 PF08317.9 MSTRG.11310.1_2 - 3.7 6.2 22.0 1.8 7.3 5.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Nup54 PF13874.4 MSTRG.11310.1_2 - 4 7.4 12.3 8.3 6.4 2.8 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 SlyX PF04102.10 MSTRG.11310.1_2 - 4.8 7.7 17.0 1.7 9.2 3.9 2.9 2 1 1 3 3 3 0 SlyX Occludin_ELL PF07303.11 MSTRG.11310.1_2 - 5.2 7.7 10.0 1.6 9.3 0.8 2.6 2 1 0 2 2 2 0 Occludin homology domain BST2 PF16716.3 MSTRG.11310.1_2 - 5.4 7.5 22.2 10 6.6 7.9 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4407 PF14362.4 MSTRG.11310.1_2 - 5.7 6.1 11.9 10 5.2 11.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) WXG100 PF06013.10 MSTRG.11310.1_2 - 5.9 7.1 12.1 9.1 6.5 0.9 3.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF2968 PF11180.6 MSTRG.11310.1_2 - 6.8 6.2 20.9 2.5 7.6 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) CENP-Q PF13094.4 MSTRG.11310.1_2 - 9.2 6.3 20.4 0.69 10.0 8.5 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit tRNA-synt_1b PF00579.23 MSTRG.10647.1_3 - 2.6e-21 76.1 0.0 5.2e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.18 MSTRG.10647.1_3 - 7.1e-21 74.0 1.1 1.2e-20 73.3 1.1 1.4 1 0 0 1 1 1 1 WHEP-TRS domain PepSY_2 PF13670.4 MSTRG.10647.1_3 - 0.15 11.9 0.3 0.3 11.0 0.3 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ank PF00023.28 MSTRG.103536.1_3 - 3.3e-06 27.2 0.4 6.2e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.5 MSTRG.103536.1_3 - 4.3e-06 27.1 0.0 5.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 MSTRG.103536.1_3 - 4.3e-06 27.0 0.0 6.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.4 MSTRG.103536.1_3 - 0.00068 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.4 MSTRG.103536.1_3 - 0.0047 17.2 0.2 0.01 16.1 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeat bZIP_2 PF07716.13 MSTRG.74879.1_2 - 5.6e-15 55.0 7.7 5.6e-15 55.0 7.7 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.19 MSTRG.74879.1_2 - 0.00012 22.0 12.5 0.0096 15.9 7.0 2.4 2 0 0 2 2 2 2 bZIP transcription factor CholecysA-Rec_N PF09193.8 MSTRG.128789.1_2 - 0.01 15.6 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal vMSA PF00695.17 MSTRG.122203.1_1 - 0.14 11.1 0.4 0.18 10.8 0.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Flexi_CP_N PF08358.8 MSTRG.80031.1_2 - 0.012 15.4 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Carlavirus coat DNA_pol_B_exo1 PF03104.17 MSTRG.63598.1_1 - 0.071 12.1 0.1 6 5.8 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase family B, exonuclease domain PNPOx_C PF10590.7 MSTRG.81398.1_2 - 6.3 6.8 5.6 31 4.6 0.1 2.4 2 1 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region DUF1576 PF07613.9 MSTRG.105399.1_3 - 0.015 14.7 0.3 0.02 14.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) 7tm_1 PF00001.19 MSTRG.138871.1_3 - 0.0021 17.2 2.5 0.0029 16.7 2.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase_Tyr PF07714.15 MSTRG.46610.1_3 - 0.043 13.0 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase YWFCY PF14293.4 MSTRG.82979.1_3 - 4.5 7.5 7.5 20 5.4 2.6 2.4 2 0 0 2 2 2 0 YWFCY protein PAD_M PF08527.8 MSTRG.131211.1_3 - 4.9e-11 42.4 0.0 5.3e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain DUF3484 PF11983.6 MSTRG.106633.1_3 - 0.94 10.5 3.6 0.49 11.4 1.7 1.5 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Porin_3 PF01459.20 MSTRG.19919.1_1 - 5.6e-12 45.6 0.1 6.8e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin DiS_P_DiS PF06750.11 MSTRG.39210.1_1 - 0.049 13.6 0.1 0.061 13.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DUF1315 PF07023.10 MSTRG.117685.1_2 - 0.048 13.6 0.2 0.059 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1315) AMP-binding PF00501.26 MSTRG.82063.1_2 - 5.6e-05 21.8 0.0 6.2e-05 21.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DNA_ligase_ZBD PF03119.14 MSTRG.64102.1_2 - 0.12 12.3 0.2 2.5 8.1 0.3 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DDE_3 PF13358.4 MSTRG.14943.1_1 - 2.1e-06 27.4 0.0 2.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SelP_N PF04592.12 MSTRG.110647.2_2 - 1.2e-84 283.3 13.4 1.2e-84 283.3 13.4 2.0 1 1 1 2 2 2 1 Selenoprotein P, N terminal region DUF3480 PF11979.6 MSTRG.10532.1_1 - 6.7e-60 202.9 0.0 7.9e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) FLILHELTA PF10306.7 MSTRG.41628.1_1 - 0.064 13.5 0.2 0.09 13.1 0.2 1.2 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA Reprolysin_2 PF13574.4 MSTRG.104853.1_2 - 2.8e-21 76.2 0.2 2.9e-21 76.1 0.2 1.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.4 MSTRG.104853.1_2 - 2.3e-19 70.2 0.2 2.5e-19 70.1 0.2 1.0 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.4 MSTRG.104853.1_2 - 1.3e-18 67.6 0.2 1.5e-18 67.3 0.2 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.4 MSTRG.104853.1_2 - 2.3e-09 37.1 1.3 3.7e-09 36.4 1.3 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.7 MSTRG.104853.1_2 - 0.0042 15.9 0.1 0.0047 15.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin PF01421.17 MSTRG.104853.1_2 - 0.017 14.9 0.0 0.022 14.6 0.0 1.5 1 1 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Metallopep PF12044.6 MSTRG.104853.1_2 - 0.073 11.5 0.5 0.099 11.1 0.5 1.2 1 0 0 1 1 1 0 Putative peptidase family Biotin_lipoyl PF00364.20 MSTRG.82711.1_2 - 4.2e-20 71.2 0.3 5.9e-20 70.7 0.3 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.4 MSTRG.82711.1_2 - 0.0013 18.4 0.1 0.52 10.1 0.1 2.2 1 1 1 2 2 2 2 Biotin-lipoyl like Calc_CGRP_IAPP PF00214.17 MSTRG.116245.1_3 - 2.6e-22 79.3 0.0 5e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family Blt1 PF12754.5 MSTRG.116245.1_3 - 0.011 15.9 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain PH PF00169.27 MSTRG.87267.1_1 - 0.029 14.7 0.1 0.034 14.5 0.1 1.1 1 0 0 1 1 1 0 PH domain PH_11 PF15413.4 MSTRG.87267.1_1 - 0.049 13.9 0.1 0.058 13.7 0.1 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Thiolase_N PF00108.21 MSTRG.128793.1_2 - 0.13 11.5 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF974 PF06159.11 MSTRG.26444.1_2 - 4.2e-85 285.3 1.6 4.8e-85 285.2 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) RCC1_2 PF13540.4 MSTRG.121931.4_2 - 4.3e-09 35.8 14.1 1.1e-08 34.5 0.1 5.2 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.16 MSTRG.121931.4_2 - 0.0021 18.5 0.4 0.0021 18.5 0.4 5.6 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat Cuticle_1 PF08140.9 MSTRG.121931.4_2 - 0.067 13.1 0.0 8.4 6.4 0.0 3.3 2 0 0 2 2 2 0 Crustacean cuticle protein repeat DUF2284 PF10050.7 MSTRG.25136.1_2 - 0.06 13.0 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Exo_endo_phos PF03372.21 MSTRG.102482.1_3 - 0.00012 22.2 0.1 0.00013 22.0 0.1 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TM1586_NiRdase PF14512.4 MSTRG.91193.1_1 - 0.025 14.0 1.0 0.036 13.5 0.3 1.5 1 1 0 1 1 1 0 Putative TM nitroreductase FtsK_SpoIIIE_N PF12538.6 MSTRG.91193.1_1 - 0.037 14.1 3.6 0.059 13.5 3.6 1.3 1 0 0 1 1 1 0 DNA transporter Ig_3 PF13927.4 MSTRG.3197.1_2 - 4.9e-06 26.9 0.0 7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 MSTRG.3197.1_2 - 8.3e-06 25.7 0.0 9.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.23 MSTRG.3197.1_2 - 0.0006 19.8 0.0 0.00074 19.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 MSTRG.3197.1_2 - 0.0047 16.9 0.0 0.01 15.9 0.0 1.5 1 1 1 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.4 MSTRG.3197.1_2 - 0.0056 16.9 0.0 0.0063 16.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.14 MSTRG.3197.1_2 - 0.065 11.8 0.0 0.066 11.8 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4303 PF14136.4 MSTRG.3197.1_2 - 0.087 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) K1 PF02960.12 MSTRG.92250.1_3 - 0.18 11.8 0.2 0.24 11.4 0.2 1.2 1 0 0 1 1 1 0 K1 glycoprotein FAM27 PF15832.3 MSTRG.108733.2_1 - 2.1 8.8 23.3 12 6.4 19.7 2.9 2 1 0 2 2 2 0 FAM27 D and E protein family Laminin_G_1 PF00054.21 MSTRG.108733.2_2 - 9.8e-25 87.1 0.1 9.8e-25 87.1 0.1 1.6 2 0 0 2 2 2 1 Laminin G domain Laminin_G_2 PF02210.22 MSTRG.108733.2_2 - 4.6e-24 85.3 0.3 8.3e-24 84.4 0.3 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.4 MSTRG.108733.2_2 - 4.3e-07 30.1 0.2 6.9e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily FAM27 PF15832.3 MSTRG.108733.2_2 - 1 9.8 17.1 2.4 8.6 17.1 1.6 1 0 0 1 1 1 0 FAM27 D and E protein family Ribosomal_L4 PF00573.20 MSTRG.33774.1_2 - 1.5e-39 135.5 0.1 2.5e-39 134.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.4 MSTRG.33774.1_2 - 6.2e-30 102.9 7.5 6.2e-30 102.9 7.5 2.3 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain Sec8_exocyst PF04048.12 MSTRG.92084.1_1 - 0.042 13.6 0.8 0.068 13.0 0.4 1.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Pkinase PF00069.23 MSTRG.91772.1_2 - 0.03 13.5 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain XTBD PF11952.6 MSTRG.91772.1_2 - 0.085 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD SLC12 PF03522.13 MSTRG.38537.1_3 - 2.6e-36 125.4 2.0 7.8e-18 64.6 0.1 2.0 1 1 1 2 2 2 2 Solute carrier family 12 DUF3915 PF13054.4 MSTRG.47907.1_1 - 0.00035 20.4 6.8 0.00048 20.0 6.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 MSTRG.47907.1_1 - 1.6 6.8 23.9 2 6.5 23.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family Atrophin-1 PF03154.13 MSTRG.47907.1_2 - 5.1 5.1 24.6 6.1 4.8 24.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family Atrophin-1 PF03154.13 MSTRG.47907.1_3 - 0.003 15.8 16.2 0.0034 15.6 16.2 1.0 1 0 0 1 1 1 1 Atrophin-1 family DUF3915 PF13054.4 MSTRG.47907.1_3 - 0.28 11.0 13.6 0.4 10.5 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Tail_VII PF17091.3 MSTRG.118311.1_2 - 0.049 13.4 0.4 0.078 12.7 0.4 1.2 1 0 0 1 1 1 0 Inovirus G7P protein DUF4421 PF14391.4 MSTRG.8343.1_2 - 0.059 12.6 0.4 0.074 12.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) zf-CCHC_4 PF14392.4 MSTRG.8343.1_2 - 2.7 7.6 8.5 1.9 8.1 0.7 3.0 2 1 1 3 3 3 0 Zinc knuckle Arf PF00025.19 MSTRG.50436.1_2 - 3.7e-56 189.2 0.8 4.5e-56 188.9 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.11 MSTRG.50436.1_2 - 2.9e-15 56.4 0.3 3.9e-15 56.0 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 MSTRG.50436.1_2 - 2.5e-13 49.8 0.7 2.9e-13 49.6 0.7 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.8 MSTRG.50436.1_2 - 9.6e-13 47.8 0.1 1.2e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.18 MSTRG.50436.1_2 - 2.5e-09 36.7 0.6 2.4e-06 26.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.21 MSTRG.50436.1_2 - 7e-07 29.2 0.1 9.7e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 MSTRG.50436.1_2 - 8.9e-07 28.4 0.5 1e-06 28.2 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 MSTRG.50436.1_2 - 0.0018 17.7 0.4 0.013 14.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.4 MSTRG.50436.1_2 - 0.026 14.4 0.1 0.12 12.2 0.0 1.8 1 1 0 2 2 2 0 AAA domain TniB PF05621.9 MSTRG.50436.1_2 - 0.04 13.0 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.16 MSTRG.50436.1_2 - 0.043 13.2 0.9 0.19 11.1 0.8 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TPM_phosphatase PF04536.12 MSTRG.50436.1_2 - 0.052 13.6 0.1 0.13 12.3 0.1 1.6 1 1 1 2 2 2 0 TPM domain DUF716 PF04819.10 MSTRG.47902.1_1 - 0.15 11.7 3.5 0.18 11.4 3.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF716) SelP_N PF04592.12 MSTRG.47902.1_3 - 0.49 9.6 7.3 0.5 9.6 7.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3398 PF11878.6 MSTRG.73970.1_1 - 2.8e-36 123.6 1.2 5e-36 122.8 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) PH PF00169.27 MSTRG.73970.1_1 - 5.5e-16 58.9 0.2 1.2e-15 57.8 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.4 MSTRG.73970.1_1 - 3.2e-05 24.2 0.0 6.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.4 MSTRG.73970.1_1 - 0.0026 17.7 0.0 0.0065 16.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.4 MSTRG.73970.1_1 - 0.023 14.8 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.4 MSTRG.73970.1_1 - 0.026 14.8 1.3 1.2 9.4 1.3 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain PGDYG PF14083.4 MSTRG.118649.1_1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 PGDYG protein C9orf72-like PF15019.4 MSTRG.117172.1_3 - 1.2e-17 64.1 0.0 1.5e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 C9orf72-like protein family Prothymosin PF03247.12 MSTRG.53355.1_3 - 2.3e-17 63.3 38.3 3.1e-17 62.9 38.3 1.1 1 0 0 1 1 1 1 Prothymosin/parathymosin family CDC45 PF02724.12 MSTRG.53355.1_3 - 0.01 14.1 10.5 0.012 13.8 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein AIG1 PF04548.14 MSTRG.121218.1_2 - 3.8e-14 52.4 5.2 3.5e-12 46.0 0.4 2.1 2 0 0 2 2 2 2 AIG1 family ABC_tran PF00005.25 MSTRG.121218.1_2 - 0.022 15.1 1.9 0.088 13.2 0.2 2.0 1 1 1 2 2 2 0 ABC transporter AAA_10 PF12846.5 MSTRG.121218.1_2 - 0.033 13.0 1.3 0.07 11.9 0.1 1.8 1 1 1 2 2 2 0 AAA-like domain Dynamin_N PF00350.21 MSTRG.121218.1_2 - 0.048 13.6 0.2 0.048 13.6 0.2 2.0 2 1 0 2 2 2 0 Dynamin family Roc PF08477.11 MSTRG.121218.1_2 - 0.053 13.6 0.7 0.24 11.5 0.1 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.21 MSTRG.121218.1_2 - 0.053 13.5 0.7 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase IIGP PF05049.11 MSTRG.121218.1_2 - 0.078 11.9 1.4 0.098 11.6 0.3 1.6 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.24 MSTRG.121218.1_2 - 0.083 12.5 0.2 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF258 PF03193.14 MSTRG.121218.1_2 - 0.084 12.6 0.3 0.099 12.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 GDI PF00996.16 MSTRG.21881.1_1 - 6.7e-13 47.8 0.0 7.3e-13 47.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.4 MSTRG.21881.1_1 - 1.2e-05 25.3 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.22 MSTRG.21881.1_1 - 0.0025 16.8 0.0 0.0028 16.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.5 MSTRG.21881.1_1 - 0.006 15.9 0.0 0.0064 15.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.10 MSTRG.21881.1_1 - 0.058 12.3 0.1 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Ldl_recept_b PF00058.15 MSTRG.46764.1_3 - 8.1e-32 109.3 0.3 1.4e-10 41.4 0.0 5.1 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B SGL PF08450.10 MSTRG.46764.1_3 - 1.4e-08 34.5 0.3 0.00031 20.3 0.2 3.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DUF5050 PF16472.3 MSTRG.46764.1_3 - 0.017 14.2 0.0 56 2.7 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5050) Arylesterase PF01731.18 MSTRG.46764.1_3 - 0.062 13.4 0.1 16 5.7 0.0 2.9 4 0 0 4 4 4 0 Arylesterase Forkhead PF00250.16 MSTRG.15650.1_1 - 2.2e-38 130.3 0.0 3.5e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain adh_short PF00106.23 MSTRG.15161.1_3 - 5.4e-38 130.3 0.1 7e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 MSTRG.15161.1_3 - 1.6e-32 112.8 0.0 2e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 MSTRG.15161.1_3 - 2.9e-08 33.7 0.2 2.1e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.17 MSTRG.15161.1_3 - 0.018 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.16 MSTRG.15161.1_3 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF912 PF06024.10 MSTRG.108629.1_1 - 0.36 11.0 4.3 2.2 8.5 1.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RhoGAP-FF1 PF16512.3 MSTRG.88703.1_2 - 5.2e-30 103.8 17.8 9.4e-28 96.6 6.5 4.2 3 1 1 4 4 4 3 p190-A and -B Rho GAPs FF domain FF PF01846.17 MSTRG.88703.1_2 - 3.3e-06 27.0 0.6 3.3e-06 27.0 0.6 3.9 5 0 0 5 5 5 1 FF domain DUF3422 PF11902.6 MSTRG.88703.1_2 - 0.16 10.9 1.7 0.34 9.8 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3422) KOG2701 PF09762.7 MSTRG.88703.1_2 - 7.5 6.6 7.5 1.3 9.1 1.8 2.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein (DUF2037) RB_A PF01858.15 MSTRG.19028.1_2 - 0.02 14.6 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain COX4 PF02936.12 MSTRG.80562.3_2 - 2.6e-59 199.1 1.3 3.2e-59 198.7 1.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Carn_acyltransf PF00755.18 MSTRG.96181.1_3 - 2.5e-17 62.6 0.0 2.8e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Striatin PF08232.10 MSTRG.28273.1_2 - 4.5e-49 166.9 5.4 2.5e-48 164.5 5.4 2.1 1 1 0 1 1 1 1 Striatin family DUF4482 PF14818.4 MSTRG.28273.1_2 - 0.012 16.3 1.7 0.034 14.9 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Cullin PF00888.20 MSTRG.7410.1_3 - 3.3e-33 115.1 1.0 3.6e-33 115.0 1.0 1.0 1 0 0 1 1 1 1 Cullin family MRP-S24 PF14955.4 MSTRG.7410.1_3 - 0.035 13.9 0.0 0.13 12.1 0.0 1.8 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S24 IGF2_C PF08365.9 MSTRG.65438.1_3 - 0.075 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide UPF0220 PF05255.9 MSTRG.3604.1_1 - 5.7e-48 162.5 3.0 7.8e-48 162.0 3.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Bacteriocin_II PF01721.16 MSTRG.3604.1_1 - 0.0031 17.5 0.4 0.0083 16.1 0.4 1.7 1 0 0 1 1 1 1 Class II bacteriocin CDC45 PF02724.12 MSTRG.55039.2_1 - 1.9 6.5 9.9 2.2 6.3 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.14 MSTRG.55039.2_1 - 2.3 7.2 7.2 3.1 6.8 7.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SWIRM-assoc_2 PF16496.3 MSTRG.55039.2_1 - 3.1 6.4 10.9 4.4 6.0 10.9 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RR_TM4-6 PF06459.10 MSTRG.55039.2_1 - 3.3 7.3 6.5 4.3 6.9 6.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 API5 PF05918.9 MSTRG.55039.2_1 - 5.1 5.7 7.4 6.3 5.4 7.4 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) HTH_Tnp_Tc3_1 PF11427.6 MSTRG.5160.1_2 - 0.025 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Tc3 transposase DDE_3 PF13358.4 MSTRG.79657.1_3 - 3e-06 26.9 1.4 4.2e-06 26.5 1.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease tify PF06200.12 MSTRG.7920.1_3 - 0.71 9.1 2.5 4.2 6.7 0.0 2.6 3 0 0 3 3 3 0 tify domain Trypsin PF00089.24 MSTRG.128975.1_2 - 2.6e-63 213.7 0.5 3.1e-63 213.4 0.5 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 MSTRG.128975.1_2 - 0.00077 19.7 0.1 0.0032 17.7 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 MSTRG.128975.1_2 - 0.0014 19.4 0.0 0.0025 18.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1777 PF08648.10 MSTRG.54528.1_1 - 0.46 10.6 22.4 0.63 10.1 22.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.7 MSTRG.54528.1_1 - 2 6.9 16.3 2.3 6.7 16.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Trypan_PARP PF05887.9 MSTRG.54528.1_1 - 3.3 7.6 7.7 4.5 7.2 7.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1777 PF08648.10 MSTRG.54528.1_2 - 2.6 8.1 23.4 3.3 7.8 23.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Trypan_PARP PF05887.9 MSTRG.54528.1_2 - 5.7 6.8 11.6 7.4 6.5 11.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MIP-T3 PF10243.7 MSTRG.54528.1_2 - 8 4.9 18.2 9 4.7 18.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.10 MSTRG.54528.1_3 - 0.29 11.2 22.9 0.06 13.5 20.0 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.7 MSTRG.54528.1_3 - 0.46 9.0 15.9 0.5 8.9 15.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Auts2 PF15336.4 MSTRG.54528.1_3 - 0.83 9.6 20.4 1.2 9.1 20.4 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Trypan_PARP PF05887.9 MSTRG.54528.1_3 - 1.3 8.9 9.0 1.6 8.6 9.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Septin PF00735.16 MSTRG.1627.1_2 - 5.1e-130 432.6 1.2 7e-130 432.2 1.2 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.21 MSTRG.1627.1_2 - 6.5e-09 35.8 0.0 2.1e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 MSTRG.1627.1_2 - 1.1e-08 35.0 0.5 1.1e-05 25.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 MSTRG.1627.1_2 - 5.9e-06 25.8 0.7 0.0033 16.9 0.1 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.14 MSTRG.1627.1_2 - 0.00015 21.0 0.5 0.00036 19.8 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Ras PF00071.20 MSTRG.1627.1_2 - 0.0016 17.9 0.5 0.0068 15.9 0.1 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.11 MSTRG.1627.1_2 - 0.0085 16.2 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.4 MSTRG.1627.1_2 - 0.017 15.3 0.0 0.052 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.4 MSTRG.1627.1_2 - 0.017 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.21 MSTRG.1627.1_2 - 0.019 14.9 5.4 0.61 10.0 0.0 3.4 3 1 1 4 4 4 0 Dynamin family AAA_29 PF13555.4 MSTRG.1627.1_2 - 0.029 14.0 0.1 0.076 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.25 MSTRG.1627.1_2 - 0.035 14.5 0.9 0.066 13.6 0.2 1.9 2 1 0 2 2 2 0 ABC transporter G-alpha PF00503.18 MSTRG.1627.1_2 - 9.4 5.1 9.4 5.1 6.0 0.2 3.1 3 1 1 4 4 4 0 G-protein alpha subunit Proteasome PF00227.24 MSTRG.66596.1_3 - 3.3e-38 130.9 0.0 4.2e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit AKNA PF12443.6 MSTRG.60234.2_3 - 0.052 14.1 0.1 0.065 13.7 0.1 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor Sema PF01403.17 MSTRG.67750.1_3 - 1.7e-18 66.5 0.0 1.8e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Sema domain 5_3_exonuc PF01367.18 MSTRG.59545.1_2 - 0.0011 19.3 1.0 0.13 12.7 0.3 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold KELK PF15796.3 MSTRG.59545.1_2 - 0.0061 16.9 12.6 0.11 12.9 4.9 2.2 2 0 0 2 2 2 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_TATA_bd PF12325.6 MSTRG.59545.1_2 - 0.016 15.3 7.8 0.11 12.6 1.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BBS2_C PF14782.4 MSTRG.59545.1_2 - 0.049 12.3 6.3 0.19 10.3 0.9 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DASH_Spc19 PF08287.9 MSTRG.59545.1_2 - 0.053 13.3 13.6 0.012 15.4 9.4 1.8 1 1 1 2 2 2 0 Spc19 XhlA PF10779.7 MSTRG.59545.1_2 - 0.071 13.2 1.9 1.5 8.9 0.3 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DUF4164 PF13747.4 MSTRG.59545.1_2 - 0.1 12.7 0.4 0.1 12.7 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF972 PF06156.11 MSTRG.59545.1_2 - 0.13 12.7 8.4 2.3 8.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.12 MSTRG.59545.1_2 - 0.21 11.2 15.8 8 6.1 14.3 2.0 1 1 1 2 2 2 0 IncA protein Vir_act_alpha_C PF10400.7 MSTRG.59545.1_2 - 0.31 11.6 6.2 0.36 11.4 0.6 2.5 3 0 0 3 3 3 0 Virulence activator alpha C-term ZapB PF06005.10 MSTRG.59545.1_2 - 0.35 11.2 10.0 3.6 8.0 2.7 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Mnd1 PF03962.13 MSTRG.59545.1_2 - 0.44 10.3 8.5 0.74 9.5 8.5 1.4 1 1 0 1 1 1 0 Mnd1 family DivIC PF04977.13 MSTRG.59545.1_2 - 0.96 9.1 10.1 4.4 7.0 1.6 2.3 2 0 0 2 2 2 0 Septum formation initiator U79_P34 PF03064.14 MSTRG.59545.1_2 - 1 8.5 8.6 2.4 7.3 8.6 1.7 1 1 0 1 1 1 0 HSV U79 / HCMV P34 Spc24 PF08286.9 MSTRG.59545.1_2 - 1.8 8.7 10.1 1.9 8.6 1.9 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF342 PF03961.11 MSTRG.59545.1_2 - 2.4 6.6 8.6 1.2 7.5 2.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF342) DUF106 PF01956.14 MSTRG.59545.1_2 - 2.4 7.7 7.9 52 3.4 7.9 2.0 1 1 0 1 1 1 0 Integral membrane protein DUF106 CCDC106 PF15794.3 MSTRG.59545.1_2 - 3.2 7.3 13.1 0.086 12.4 3.5 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 Fmp27_WPPW PF10359.7 MSTRG.59545.1_2 - 5.5 5.6 13.4 1.1 7.9 4.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain APG6 PF04111.10 MSTRG.59545.1_2 - 8.3 5.6 13.2 8.3 5.6 1.8 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 Sialidase_penC PF12135.6 MSTRG.77803.1_1 - 0.056 13.0 0.4 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Sialidase enzyme penultimate C terminal domain CobS_N PF12556.6 MSTRG.34727.2_3 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal FA_desaturase PF00487.22 MSTRG.2568.1_1 - 4.6 6.9 5.4 4.7 6.8 5.4 1.0 1 0 0 1 1 1 0 Fatty acid desaturase I-set PF07679.14 MSTRG.130620.1_1 - 1.2e-18 66.8 0.0 1.9e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.130620.1_1 - 8.2e-13 48.6 0.1 1.5e-12 47.8 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 MSTRG.130620.1_1 - 2.2e-09 37.2 0.0 3.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.130620.1_1 - 1.9e-08 34.4 0.0 4.7e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 MSTRG.130620.1_1 - 1.8e-05 24.7 2.4 0.0025 17.8 0.3 2.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain WD40 PF00400.30 MSTRG.18266.1_3 - 4.8e-15 55.6 1.7 1.3e-05 25.7 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat BBS2_Mid PF14783.4 MSTRG.18266.1_3 - 0.0051 16.7 0.0 3.7 7.5 0.0 2.5 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Mago-bind PF09282.8 MSTRG.124534.1_2 - 1.8e-13 49.9 1.9 3.3e-13 49.1 1.9 1.4 1 0 0 1 1 1 1 Mago binding GvpG PF05120.10 MSTRG.124534.1_2 - 0.051 13.4 0.8 0.097 12.6 0.8 1.4 1 0 0 1 1 1 0 Gas vesicle protein G Bac_globin PF01152.19 MSTRG.124534.1_3 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial-like globin SPDY PF03771.14 MSTRG.2924.1_1 - 0.085 12.7 2.4 4 7.3 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF317) PGM_PMM_IV PF00408.18 MSTRG.2924.1_1 - 0.087 12.9 0.0 31 4.7 0.0 3.0 1 1 3 4 4 4 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF3185 PF11381.6 MSTRG.2924.1_1 - 4 7.4 6.9 5.3 7.0 1.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3185) Antimicrobial14 PF08109.9 MSTRG.2924.1_2 - 0.0021 17.9 26.0 2.6 8.0 0.3 5.1 5 0 0 5 5 5 5 Lactocin 705 family IQ PF00612.25 MSTRG.2924.1_3 - 0.029 14.0 13.1 24 5.0 0.1 5.1 5 0 0 5 5 5 0 IQ calmodulin-binding motif UIM PF02809.18 MSTRG.40542.1_2 - 2.1e-10 39.6 14.4 1.2e-05 24.8 0.3 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif DNA_pol3_tau_5 PF12170.6 MSTRG.40542.1_2 - 0.012 15.6 1.8 0.015 15.2 1.8 1.1 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha DUF587 PF04532.10 MSTRG.40542.1_2 - 0.052 12.7 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF587) NAD_kinase PF01513.19 MSTRG.138810.1_3 - 5.7e-20 71.5 0.0 7.3e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.22 MSTRG.138810.1_3 - 0.027 14.0 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CAP_GLY PF01302.23 MSTRG.53857.1_2 - 2.5e-15 56.1 0.0 4.5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain UCH PF00443.27 MSTRG.53857.1_2 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FGF PF00167.16 MSTRG.66508.1_1 - 3.6e-42 143.3 0.1 4.6e-42 142.9 0.1 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 MSTRG.66508.1_1 - 0.018 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Fascin domain IL1 PF00340.17 MSTRG.66508.1_1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Interleukin-1 / 18 LRR_8 PF13855.4 MSTRG.135113.1_1 - 3.2e-17 61.9 14.5 1.3e-13 50.3 6.2 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.5 MSTRG.135113.1_1 - 2.6e-12 46.6 15.0 3.3e-07 30.4 5.6 2.2 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 MSTRG.135113.1_1 - 9.5e-05 22.2 12.7 0.064 13.6 0.6 4.3 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.4 MSTRG.135113.1_1 - 0.03 14.2 13.6 1.9 8.6 0.2 4.6 3 1 2 5 5 5 0 Leucine Rich repeat Dendrin PF15498.4 MSTRG.135113.1_1 - 3.7 6.0 11.6 4.4 5.8 11.6 1.0 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin DUF1682 PF07946.12 MSTRG.135113.1_1 - 6.4 5.8 17.2 7.5 5.5 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NinG PF05766.10 MSTRG.135113.1_1 - 7.1 6.4 17.3 9.7 6.0 17.3 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DDRGK PF09756.7 MSTRG.135113.1_1 - 9.9 5.6 24.9 14 5.1 24.9 1.1 1 0 0 1 1 1 0 DDRGK domain zf-CCCH PF00642.22 MSTRG.49314.1_3 - 2.6e-08 33.4 0.9 3.7e-08 32.9 0.9 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1324 PF07038.9 MSTRG.51310.1_2 - 0.096 12.8 1.7 0.12 12.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) DUF3678 PF12435.6 MSTRG.47808.1_1 - 0.2 10.8 1.4 0.42 9.8 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) RVT_1 PF00078.25 MSTRG.84123.1_2 - 2.9e-05 23.6 0.0 3.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank PF00023.28 MSTRG.24098.1_3 - 1.2e-30 104.4 7.3 2.5e-07 30.7 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.4 MSTRG.24098.1_3 - 7e-30 102.5 1.3 2.8e-10 40.1 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 MSTRG.24098.1_3 - 1.6e-27 92.4 0.7 2.6e-05 24.1 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.4 MSTRG.24098.1_3 - 3.4e-27 94.3 0.3 5.2e-10 39.5 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.5 MSTRG.24098.1_3 - 5e-27 94.2 0.5 6.3e-11 42.6 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) RrnaAD PF00398.18 MSTRG.107584.1_2 - 2.4e-17 62.7 0.0 2.7e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.4 MSTRG.107584.1_2 - 4.8e-05 23.9 0.0 5.2e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 MSTRG.107584.1_2 - 0.0018 18.7 0.0 0.0021 18.5 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.16 MSTRG.107584.1_2 - 0.068 12.7 0.0 0.077 12.5 0.0 1.0 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.5 MSTRG.107584.1_2 - 0.15 11.8 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Gp5_C PF06715.10 MSTRG.80039.1_3 - 0.55 10.4 5.1 0.62 10.2 2.1 2.0 1 1 1 2 2 2 0 Gp5 C-terminal repeat (3 copies) zf-H2C2_2 PF13465.4 MSTRG.77129.1_3 - 2.5e-15 56.0 32.0 2.7e-06 27.4 6.0 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.77129.1_3 - 1.1e-11 44.3 27.6 0.00016 21.8 3.1 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.77129.1_3 - 6.1e-06 26.5 26.9 0.0053 17.4 2.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HE PF16278.3 MSTRG.77129.1_3 - 0.00075 19.8 18.2 0.023 15.0 0.9 3.1 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.5 MSTRG.77129.1_3 - 0.0018 18.4 19.1 0.0044 17.2 0.7 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.8 MSTRG.77129.1_3 - 0.0067 16.4 10.4 1.6 8.8 0.1 3.1 2 1 1 3 3 3 2 Zinc ribbon domain zinc_ribbon_5 PF13719.4 MSTRG.77129.1_3 - 0.018 14.7 6.0 6.5 6.5 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_jaz PF12171.6 MSTRG.77129.1_3 - 0.023 14.9 13.2 0.21 11.8 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ZZ PF00569.15 MSTRG.77129.1_3 - 0.049 13.3 7.9 1.2 8.9 0.4 3.2 3 0 0 3 3 3 0 Zinc finger, ZZ type Evr1_Alr PF04777.11 MSTRG.77129.1_3 - 0.08 13.3 8.7 0.088 13.2 2.7 2.9 1 1 1 2 2 2 0 Erv1 / Alr family Desulfoferrod_N PF06397.10 MSTRG.77129.1_3 - 0.086 12.3 8.0 0.43 10.1 0.3 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_8 PF15909.3 MSTRG.77129.1_3 - 0.096 12.9 11.6 0.26 11.5 6.7 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-DBF PF07535.10 MSTRG.77129.1_3 - 0.2 11.7 10.4 1.9 8.5 0.1 3.3 3 0 0 3 3 3 0 DBF zinc finger zinc-ribbons_6 PF07191.10 MSTRG.77129.1_3 - 0.2 11.5 8.2 2.2 8.2 2.0 3.0 1 1 1 2 2 2 0 zinc-ribbons DUF3268 PF11672.6 MSTRG.77129.1_3 - 0.24 11.6 6.4 0.2 11.9 1.0 2.2 1 1 1 2 2 2 0 zinc-finger-containing domain zf-trcl PF13451.4 MSTRG.77129.1_3 - 0.26 11.1 6.1 4.5 7.1 0.5 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain GATA PF00320.25 MSTRG.77129.1_3 - 0.3 10.6 5.1 6.7 6.3 0.1 3.3 2 1 1 3 3 3 0 GATA zinc finger zf-HIT PF04438.14 MSTRG.77129.1_3 - 0.32 10.8 9.7 11 5.9 0.1 3.3 3 0 0 3 3 3 0 HIT zinc finger GAGA PF09237.9 MSTRG.77129.1_3 - 0.57 9.9 10.4 1.5 8.5 0.1 3.1 1 1 2 3 3 3 0 GAGA factor FYDLN_acid PF09538.8 MSTRG.77129.1_3 - 1.1 9.9 3.2 7.6 7.1 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.5 MSTRG.77129.1_3 - 1.2 9.4 15.9 2.3 8.5 0.3 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SR-25 PF10500.7 MSTRG.133744.1_1 - 8.4 5.8 9.6 10 5.5 9.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-RING_2 PF13639.4 MSTRG.102593.1_2 - 3.8e-12 46.1 9.1 3.8e-12 46.1 9.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.3 MSTRG.102593.1_2 - 2.3e-09 36.7 5.9 5.8e-09 35.4 5.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 MSTRG.102593.1_2 - 6e-09 35.5 9.5 1.4e-08 34.3 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 MSTRG.102593.1_2 - 1e-08 35.2 9.1 3.6e-08 33.4 9.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 MSTRG.102593.1_2 - 3.7e-08 33.0 9.2 3.7e-08 33.0 9.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 MSTRG.102593.1_2 - 2e-05 24.3 7.8 2e-05 24.3 7.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 MSTRG.102593.1_2 - 3.6e-05 23.4 7.9 3.6e-05 23.4 7.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 MSTRG.102593.1_2 - 6.3e-05 22.8 7.8 0.00015 21.5 7.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.4 MSTRG.102593.1_2 - 0.00019 21.2 2.7 0.00019 21.2 2.7 2.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.5 MSTRG.102593.1_2 - 0.00057 19.7 5.1 0.0018 18.1 5.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.3 MSTRG.102593.1_2 - 0.075 12.5 6.2 0.22 11.1 6.2 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-TFIIIC PF12660.5 MSTRG.102593.1_2 - 0.093 12.6 7.9 0.036 13.9 1.8 2.3 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex RINGv PF12906.5 MSTRG.102593.1_2 - 0.22 11.6 9.7 0.51 10.4 9.7 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.4 MSTRG.102593.1_2 - 0.36 10.6 12.7 0.04 13.7 7.5 2.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.6 MSTRG.102593.1_2 - 0.64 10.1 8.0 4.9 7.3 8.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.3 MSTRG.102593.1_2 - 9.7 6.2 12.2 0.38 10.7 5.5 2.2 2 0 0 2 2 1 0 Zinc-finger Robl_LC7 PF03259.15 MSTRG.22622.1_1 - 3.3e-17 61.9 0.1 4.5e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF4759 PF15954.3 MSTRG.22622.1_1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4759) CIMR PF00878.16 MSTRG.31724.1_1 - 1.8e-42 144.7 10.5 5e-20 71.9 0.3 3.1 3 0 0 3 3 3 3 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.8 MSTRG.31724.1_1 - 2e-12 47.4 9.1 1e-07 32.0 0.1 3.8 1 1 2 3 3 3 3 Autophagy-related protein 27 PRKCSH_1 PF13015.4 MSTRG.31724.1_1 - 0.014 15.0 6.9 0.29 10.7 0.1 3.2 3 0 0 3 3 3 0 Glucosidase II beta subunit-like protein PA PF02225.20 MSTRG.117807.1_3 - 1.6e-06 28.0 0.0 1.7e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 PA domain ATP_synt_H PF05493.11 MSTRG.73652.1_3 - 3.6e-21 75.3 5.9 3.6e-21 75.3 5.9 2.6 2 0 0 2 2 2 1 ATP synthase subunit H HTH_23 PF13384.4 MSTRG.106184.1_1 - 3.2e-05 23.4 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.4 MSTRG.106184.1_1 - 0.00064 19.3 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.4 MSTRG.106184.1_1 - 0.006 16.6 0.0 0.008 16.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.13 MSTRG.106184.1_1 - 0.036 14.0 0.0 0.066 13.2 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_psq PF05225.14 MSTRG.106184.1_1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF1031 PF06275.9 MSTRG.91239.1_1 - 0.02 15.0 0.4 0.045 13.9 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1031) RRM_1 PF00076.20 MSTRG.52212.1_3 - 1.6e-05 24.5 0.0 3.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4408 PF14364.4 MSTRG.45987.1_2 - 0.077 12.6 0.5 0.11 12.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) DUF2157 PF09925.7 MSTRG.18869.1_3 - 0.018 14.7 0.2 0.02 14.6 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Antimicrobial14 PF08109.9 MSTRG.120997.1_1 - 1.7 8.6 12.2 2.5 8.1 0.5 3.2 3 0 0 3 3 3 0 Lactocin 705 family DUF4278 PF14105.4 MSTRG.120997.1_2 - 2.5 8.4 11.9 1.9e+02 2.4 11.9 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4278) Sec10 PF07393.9 MSTRG.71178.1_2 - 1.1e-20 73.5 1.7 1.2e-20 73.4 1.7 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 ABC2_membrane PF01061.22 MSTRG.109534.1_3 - 3.1e-21 75.6 14.1 3.6e-21 75.4 14.1 1.0 1 0 0 1 1 1 1 ABC-2 type transporter DiS_P_DiS PF06750.11 MSTRG.140112.1_3 - 0.0093 15.9 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain tRNA-synt_2 PF00152.18 MSTRG.40593.1_2 - 7.2e-38 130.3 0.1 7.6e-38 130.2 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) ArsP_2 PF11449.6 MSTRG.53514.1_3 - 0.14 11.2 0.3 0.15 11.1 0.3 1.0 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter Torus PF16131.3 MSTRG.35672.1_1 - 0.034 14.7 0.0 0.042 14.4 0.0 1.2 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.4 MSTRG.35672.1_1 - 0.087 13.2 2.3 0.15 12.5 2.3 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C2H2_4 PF13894.4 MSTRG.80169.1_3 - 1.4e-05 25.4 8.2 0.048 14.4 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.5 MSTRG.80169.1_3 - 1.5e-05 25.0 7.2 0.045 14.0 2.9 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 MSTRG.80169.1_3 - 4.9e-05 23.4 5.6 0.09 13.0 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.3 MSTRG.80169.1_3 - 0.0042 17.4 1.2 1.5 9.2 0.0 2.2 2 0 0 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.24 MSTRG.80169.1_3 - 0.005 17.1 8.3 0.062 13.7 0.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.5 MSTRG.80169.1_3 - 0.0079 16.4 2.7 0.075 13.2 2.7 2.0 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF3222 PF11519.6 MSTRG.80169.1_3 - 0.014 15.4 0.8 0.031 14.4 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3222) zf-H2C2_2 PF13465.4 MSTRG.80169.1_3 - 0.24 11.8 8.4 0.47 10.9 1.3 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.84392.1_2 - 0.15 12.8 3.1 0.26 12.1 3.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF320 PF03777.11 MSTRG.133411.1_1 - 0.63 9.8 3.4 0.21 11.4 0.5 1.7 2 0 0 2 2 2 0 Small secreted domain (DUF320) WD40 PF00400.30 MSTRG.133411.1_2 - 3.3e-05 24.4 7.9 0.49 11.2 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.133411.1_2 - 0.026 14.7 0.0 2.2 8.5 0.0 3.4 2 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Atg14 PF10186.7 MSTRG.57546.1_2 - 2.4e-09 36.6 0.0 2.4e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.23 MSTRG.119871.1_3 - 7.1e-11 41.8 0.0 7.7e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.119871.1_3 - 9.2e-05 21.7 0.0 9.2e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 MSTRG.119871.1_3 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MBF1 PF08523.8 MSTRG.76785.1_3 - 6.8e-23 80.8 6.2 1.1e-22 80.1 6.2 1.3 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.20 MSTRG.76785.1_3 - 2.7e-09 36.8 0.1 5e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.4 MSTRG.76785.1_3 - 0.041 14.1 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain ANAPC10 PF03256.14 MSTRG.110543.1_2 - 0.075 12.5 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) RVT_1 PF00078.25 MSTRG.60743.1_1 - 0.00035 20.0 0.0 0.00041 19.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3915 PF13054.4 MSTRG.73647.1_1 - 0.2 11.5 8.4 0.48 10.3 8.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF3915 PF13054.4 MSTRG.73647.1_2 - 1.2 9.0 8.5 2.1 8.2 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3915 PF13054.4 MSTRG.73647.1_3 - 1.4 8.8 9.8 2 8.3 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 MSTRG.73647.1_3 - 4 5.5 14.1 6 4.9 14.1 1.3 1 0 0 1 1 1 0 Atrophin-1 family Antimicrobial14 PF08109.9 MSTRG.70782.1_1 - 0.0019 18.1 11.9 2 8.4 0.5 3.1 3 0 0 3 3 3 3 Lactocin 705 family zf-FCS PF06467.12 MSTRG.70782.1_1 - 0.0096 15.7 0.3 24 4.9 0.0 3.0 1 1 2 3 3 3 3 MYM-type Zinc finger with FCS sequence motif MitoNEET_N PF10660.7 MSTRG.70782.1_1 - 0.11 12.4 0.2 13 5.8 0.0 2.6 1 1 2 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus IQ PF00612.25 MSTRG.70782.1_2 - 0.01 15.4 6.3 13 5.8 0.5 3.7 3 1 0 3 3 3 0 IQ calmodulin-binding motif Glyco_hydro_65C PF03633.13 MSTRG.70782.1_2 - 1.2 9.0 5.6 5.2 6.9 0.2 2.9 1 1 2 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain DUF4278 PF14105.4 MSTRG.70782.1_2 - 1.3 9.4 15.7 2.1e+02 2.3 15.7 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4278) Rax2 PF12768.5 MSTRG.91004.1_3 - 0.11 11.9 0.9 0.14 11.6 0.9 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity PRK PF00485.16 MSTRG.116165.1_3 - 7.4e-18 64.9 0.0 8.9e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.10 MSTRG.116165.1_3 - 1.4e-06 28.2 0.0 1.8e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.4 MSTRG.116165.1_3 - 3.8e-05 23.7 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain CoaE PF01121.18 MSTRG.116165.1_3 - 0.0035 16.9 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.4 MSTRG.116165.1_3 - 0.012 16.0 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.10 MSTRG.116165.1_3 - 0.021 14.0 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.12 MSTRG.116165.1_3 - 0.06 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.4 MSTRG.116165.1_3 - 0.069 13.4 0.0 0.088 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.8 MSTRG.116165.1_3 - 0.11 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.18 MSTRG.116165.1_3 - 0.12 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase fn3 PF00041.19 MSTRG.44998.1_2 - 6.2e-10 39.1 0.4 7.6e-10 38.9 0.4 1.0 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.3 MSTRG.44998.1_2 - 0.0032 17.9 0.6 0.039 14.4 0.6 2.0 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Choline_transpo PF04515.10 MSTRG.3811.1_3 - 7.4e-09 35.1 4.0 7.4e-09 35.1 4.0 2.2 3 0 0 3 3 3 1 Plasma-membrane choline transporter Mucin PF01456.15 MSTRG.71767.1_2 - 0.15 11.9 17.3 0.17 11.7 17.3 1.0 1 0 0 1 1 1 0 Mucin-like glycoprotein Shisa PF13908.4 MSTRG.71767.1_2 - 1.3 9.1 5.2 1.4 9.0 5.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RNA_POL_M_15KD PF02150.14 MSTRG.33017.1_3 - 1.4e-16 59.9 5.0 1.4e-16 59.9 5.0 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.16 MSTRG.33017.1_3 - 6.6e-13 48.1 8.7 9.2e-13 47.7 1.1 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Ogr_Delta PF04606.10 MSTRG.33017.1_3 - 0.00035 20.4 1.5 0.00035 20.4 1.5 2.6 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.4 MSTRG.33017.1_3 - 0.0023 18.3 7.0 0.029 14.7 0.2 2.7 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain CpXC PF14353.4 MSTRG.33017.1_3 - 0.014 15.3 3.1 2.8 7.8 0.1 2.5 2 0 0 2 2 2 0 CpXC protein DZR PF12773.5 MSTRG.33017.1_3 - 0.017 15.0 1.9 0.017 15.0 1.9 3.4 3 1 1 4 4 4 0 Double zinc ribbon Lar_restr_allev PF14354.4 MSTRG.33017.1_3 - 0.033 14.4 1.0 0.033 14.4 1.0 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.10 MSTRG.33017.1_3 - 0.036 13.4 0.2 0.036 13.4 0.2 2.6 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C4_Topoisom PF01396.17 MSTRG.33017.1_3 - 2.6 7.8 8.6 1.6 8.4 0.8 2.6 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Zn_Tnp_IS1595 PF12760.5 MSTRG.33017.1_3 - 3.8 7.4 12.6 0.13 12.1 2.3 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain betaPIX_CC PF16523.3 MSTRG.53661.1_2 - 0.071 12.8 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 betaPIX coiled coil WBP-1 PF11669.6 MSTRG.100125.1_3 - 1.5 9.4 4.6 4.5 7.8 0.2 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 Vps16_C PF04840.10 MSTRG.101816.2_3 - 3.4e-13 49.2 4.0 8.8e-08 31.4 1.3 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region 7tm_1 PF00001.19 MSTRG.42724.1_2 - 2.5e-15 56.3 1.1 2.5e-15 56.3 1.1 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) PH_BEACH PF14844.4 MSTRG.54760.1_1 - 0.098 12.6 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH EF-hand_7 PF13499.4 MSTRG.105235.1_2 - 3.9e-10 39.9 1.0 5.6e-10 39.4 1.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.30 MSTRG.105235.1_2 - 2e-09 36.2 6.9 7.3e-05 21.9 1.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.4 MSTRG.105235.1_2 - 2.3e-08 33.2 2.4 0.00024 20.7 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.4 MSTRG.105235.1_2 - 1.9e-07 30.2 4.0 0.00075 18.8 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.4 MSTRG.105235.1_2 - 0.00012 21.7 4.1 0.014 15.0 1.7 2.3 1 1 1 2 2 2 2 EF-hand domain pair Keratin_assoc PF09775.7 MSTRG.105235.1_3 - 0.015 14.8 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Orn_Arg_deC_N PF02784.14 MSTRG.79455.2_2 - 3.7e-27 95.2 0.0 4.2e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain AP_endonuc_2 PF01261.22 MSTRG.79455.2_2 - 0.0071 15.7 0.0 0.0087 15.4 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_DAP_Arg_deC PF00278.20 MSTRG.79455.2_2 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain NDUF_B5 PF09781.7 MSTRG.143059.1_2 - 2.5e-89 297.7 0.0 2.8e-89 297.5 0.0 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Peptidase_C5 PF00770.16 MSTRG.143059.1_2 - 0.065 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus endoprotease DUF3749 PF12568.6 MSTRG.143059.1_2 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4839 PF16127.3 MSTRG.123460.1_2 - 0.096 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4839) CUB PF00431.18 MSTRG.126823.1_2 - 3.1e-59 198.0 0.1 8.9e-29 99.9 0.1 2.1 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.18 MSTRG.126823.1_2 - 5.9e-06 25.9 0.2 0.021 14.4 0.0 2.5 2 0 0 2 2 2 2 CUB-like domain ORMDL PF04061.12 MSTRG.52929.2_2 - 4.9e-52 175.2 4.2 6.2e-52 174.9 4.2 1.1 1 0 0 1 1 1 1 ORMDL family DDE_3 PF13358.4 MSTRG.16721.1_1 - 0.00082 19.0 0.2 0.00082 19.0 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sec3_C_2 PF15278.4 MSTRG.16721.1_2 - 0.12 12.6 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DUF1338 PF07063.11 MSTRG.57160.1_3 - 0.039 13.0 0.1 0.051 12.6 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1338) Repressor_Mnt PF11423.6 MSTRG.136466.1_2 - 0.18 11.5 0.8 0.31 10.7 0.8 1.3 1 0 0 1 1 1 0 Regulatory protein Mnt F_actin_bind PF08919.8 MSTRG.117533.1_1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 F-actin binding IFRD_C PF04836.10 MSTRG.66840.1_2 - 3.8e-23 81.7 0.4 5.7e-23 81.1 0.4 1.3 1 0 0 1 1 1 1 Interferon-related protein conserved region SH3_9 PF14604.4 MSTRG.50369.1_1 - 0.036 13.8 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain SH3_1 PF00018.26 MSTRG.50369.1_1 - 0.088 12.3 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 SH3 domain Atrophin-1 PF03154.13 MSTRG.107554.1_1 - 6.5 4.8 24.1 8 4.5 24.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family MtrD PF04207.10 MSTRG.44805.1_3 - 0.026 14.1 0.1 0.03 13.9 0.1 1.0 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D DUF843 PF05814.9 MSTRG.44805.1_3 - 0.03 14.2 0.2 0.034 14.0 0.2 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) PGI PF00342.17 MSTRG.46464.1_1 - 5e-31 107.7 0.1 6.8e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoglucose isomerase Urease_beta PF00699.18 MSTRG.46464.1_1 - 0.003 17.4 0.1 0.006 16.4 0.1 1.5 1 0 0 1 1 1 1 Urease beta subunit Anoctamin PF04547.10 MSTRG.122457.1_2 - 2.7e-78 263.6 4.0 3e-78 263.4 4.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF4793 PF16041.3 MSTRG.122457.1_2 - 0.059 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) ABC2_membrane_3 PF12698.5 MSTRG.122457.1_2 - 0.2 10.6 4.3 0.15 11.0 0.1 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein CS PF04969.14 MSTRG.16075.3_1 - 5.8e-10 39.9 0.0 8.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 CS domain CHORD PF04968.10 MSTRG.16075.3_1 - 8e-09 35.9 3.8 8e-09 35.9 3.8 2.0 2 0 0 2 2 2 1 CHORD DUF1508 PF07411.10 MSTRG.16075.3_2 - 0.011 15.4 0.8 11 5.8 0.1 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF1508) fn3 PF00041.19 MSTRG.45384.2_3 - 4.9e-43 145.3 0.0 8.8e-14 51.5 0.0 3.9 4 0 0 4 4 4 3 Fibronectin type III domain I-set PF07679.14 MSTRG.45384.2_3 - 3.2e-41 139.1 0.0 1.4e-17 63.4 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.45384.2_3 - 2e-26 92.3 0.3 4.7e-13 49.4 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.23 MSTRG.45384.2_3 - 1.7e-13 50.4 0.1 7.6e-09 35.5 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.45384.2_3 - 1.4e-12 47.7 0.4 3.4e-06 27.2 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.15 MSTRG.45384.2_3 - 6e-08 32.7 0.1 0.26 11.3 0.0 4.6 3 1 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.10 MSTRG.45384.2_3 - 1.5e-06 28.1 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain RVT_1 PF00078.25 MSTRG.15852.1_1 - 2e-07 30.6 0.1 2.1e-07 30.5 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1640 PF07798.9 MSTRG.102026.4_1 - 2.6e-53 180.5 16.5 4.4e-53 179.8 16.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2408 PF10303.7 MSTRG.102026.4_1 - 2.8 8.4 9.2 5.1 7.5 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF972 PF06156.11 MSTRG.102026.4_1 - 9.2 6.8 13.2 0.51 10.8 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Vinculin PF01044.17 MSTRG.116551.1_2 - 1.8e-23 82.7 0.6 2.2e-23 82.4 0.6 1.0 1 0 0 1 1 1 1 Vinculin family HAUS5 PF14817.4 MSTRG.70978.1_2 - 4.2e-29 101.6 0.5 4.5e-29 101.4 0.5 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 SAM_PNT PF02198.14 MSTRG.52880.2_2 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain TMEM252 PF15664.3 MSTRG.52880.2_2 - 0.14 11.7 1.8 0.2 11.3 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF4371 PF14291.4 MSTRG.101457.1_1 - 1.9e-11 44.0 0.1 1.2e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4371) PAS_11 PF14598.4 MSTRG.138610.1_2 - 2.6e-22 79.0 0.1 3.6e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.10 MSTRG.138610.1_2 - 6.1e-12 45.5 0.0 8.2e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS PF00989.23 MSTRG.138610.1_2 - 8e-10 38.6 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.8 MSTRG.138610.1_2 - 0.0094 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold WD40 PF00400.30 MSTRG.81946.1_3 - 1.7e-09 38.0 1.6 0.00021 21.9 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.81946.1_3 - 0.02 15.1 0.0 0.052 13.7 0.0 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1981 PF09324.8 MSTRG.24229.1_1 - 6.1e-11 41.9 2.0 1.2e-09 37.7 1.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1981) LRR_6 PF13516.4 MSTRG.1873.1_3 - 4.5e-12 44.9 9.4 0.00021 21.0 0.1 3.9 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.5 MSTRG.1873.1_3 - 0.048 13.9 12.5 0.26 11.6 3.3 3.7 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 MSTRG.1873.1_3 - 0.062 12.9 5.2 3.6 7.3 2.9 3.3 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.31 MSTRG.1873.1_3 - 3.9 8.2 12.3 9.9 7.0 0.1 4.6 6 1 0 6 6 6 0 Leucine Rich Repeat SOUL PF04832.10 MSTRG.96705.1_3 - 1.1e-32 113.4 0.0 1.5e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 SOUL heme-binding protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.4178.1_1 - 7.3e-12 45.2 0.6 9.3e-12 44.9 0.6 1.1 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.4 MSTRG.4178.1_1 - 0.0058 16.1 0.2 0.0072 15.8 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.9 MSTRG.4178.1_1 - 0.079 11.8 0.2 0.083 11.7 0.2 1.0 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Ras PF00071.20 MSTRG.70334.2_3 - 5.9e-09 35.6 0.1 8.9e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.11 MSTRG.70334.2_3 - 2.4e-06 27.6 0.0 3.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.4 MSTRG.70334.2_3 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain TniB PF05621.9 MSTRG.70334.2_3 - 0.2 10.7 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein AMP-binding PF00501.26 MSTRG.142337.1_2 - 0.0012 17.4 0.0 0.0012 17.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Cation_ATPase PF13246.4 MSTRG.91887.1_1 - 7.6e-14 51.5 0.0 6.4e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.24 MSTRG.91887.1_1 - 2.5e-06 27.8 0.6 9.3e-05 22.7 0.6 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FimH_man-bind PF09160.8 MSTRG.91887.1_1 - 0.00026 20.5 0.0 0.0019 17.8 0.1 2.2 2 0 0 2 2 2 1 FimH, mannose binding LLGL PF08366.11 MSTRG.113760.1_1 - 1.9e-07 31.2 0.1 3.4e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 LLGL2 WD40 PF00400.30 MSTRG.113760.1_1 - 9.1e-05 23.0 1.3 0.017 15.8 0.8 3.2 2 1 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.113760.1_1 - 0.0095 16.1 0.0 0.12 12.5 0.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Xlink PF00193.15 MSTRG.3312.1_2 - 0.0056 16.9 0.1 0.0095 16.2 0.1 1.3 1 0 0 1 1 1 1 Extracellular link domain HTH_23 PF13384.4 MSTRG.5762.1_3 - 0.0014 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.17 MSTRG.5762.1_3 - 0.0015 18.2 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.14 MSTRG.5762.1_3 - 0.0041 16.5 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.4 MSTRG.5762.1_3 - 0.0045 16.8 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix PIP5K PF01504.16 MSTRG.5762.1_3 - 0.033 13.3 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Terminase_5 PF06056.10 MSTRG.5762.1_3 - 0.073 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_24 PF13412.4 MSTRG.5762.1_3 - 0.096 12.1 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.18 MSTRG.5762.1_3 - 0.11 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Fe_dep_repress PF01325.17 MSTRG.5762.1_3 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.8 MSTRG.5762.1_3 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain zf-RING_UBOX PF13445.4 MSTRG.681.1_2 - 1.2e-11 44.3 4.7 1.2e-11 44.3 4.7 3.0 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 MSTRG.681.1_2 - 3.2e-10 39.6 11.1 3.2e-10 39.6 11.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.22 MSTRG.681.1_2 - 8.1e-10 38.6 2.0 8.1e-10 38.6 2.0 3.4 2 1 0 2 2 1 1 B-box zinc finger zf-C3HC4_2 PF13923.4 MSTRG.681.1_2 - 2.9e-09 36.5 10.3 2.9e-09 36.5 10.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 MSTRG.681.1_2 - 4e-08 32.9 9.8 4e-08 32.9 9.8 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 MSTRG.681.1_2 - 4.2e-08 32.9 9.5 4.2e-08 32.9 9.5 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.4 MSTRG.681.1_2 - 4.5e-08 33.0 7.7 4.5e-08 33.0 7.7 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.4 MSTRG.681.1_2 - 2.3e-07 30.8 9.9 2.3e-07 30.8 9.9 2.4 2 0 0 2 2 2 1 Ring finger domain U-box PF04564.13 MSTRG.681.1_2 - 1.7e-06 27.9 0.2 8.3e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 U-box domain Prok-RING_4 PF14447.4 MSTRG.681.1_2 - 3.7e-06 26.5 11.9 3.7e-06 26.5 11.9 3.0 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.3 MSTRG.681.1_2 - 1.6e-05 24.8 8.3 1.6e-05 24.8 8.3 2.2 2 1 1 3 3 2 1 zinc RING finger of MSL2 zf-RING_6 PF14835.4 MSTRG.681.1_2 - 5.5e-05 22.8 4.6 5.5e-05 22.8 4.6 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.5 MSTRG.681.1_2 - 0.0046 17.1 7.7 0.0046 17.1 7.7 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain TMEM219 PF14940.4 MSTRG.681.1_2 - 0.016 14.7 2.2 0.62 9.5 0.3 2.2 2 0 0 2 2 2 0 Transmembrane 219 zf-RING_4 PF14570.4 MSTRG.681.1_2 - 0.095 12.3 17.6 0.12 12.0 7.0 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain CSG2 PF16965.3 MSTRG.80754.1_1 - 0.054 12.3 0.1 0.054 12.3 0.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator VMA21 PF09446.8 MSTRG.80754.1_1 - 0.17 11.9 1.6 0.28 11.2 1.6 1.4 1 0 0 1 1 1 0 VMA21-like domain Y_phosphatase PF00102.25 MSTRG.12390.1_2 - 9.6e-14 51.4 0.4 1.4e-13 50.9 0.1 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase zf-H2C2_2 PF13465.4 MSTRG.32202.1_1 - 1.4e-87 284.4 120.5 2.3e-09 37.1 1.2 15.1 15 0 0 15 15 15 14 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.32202.1_1 - 9.9e-64 208.3 142.5 2.2e-06 27.7 1.2 14.7 15 0 0 15 15 15 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.32202.1_1 - 1.1e-39 131.4 152.3 0.00017 22.0 0.7 15.0 16 0 0 16 16 15 14 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.32202.1_1 - 2.7e-15 55.8 112.7 3.8e-05 23.4 1.6 14.6 14 2 0 14 14 14 8 C2H2-type zinc finger zf-met PF12874.5 MSTRG.32202.1_1 - 6.7e-15 54.8 130.2 0.0089 16.3 0.7 14.8 15 0 0 15 15 14 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 MSTRG.32202.1_1 - 4.2e-11 42.7 95.5 0.048 13.9 0.2 14.5 14 0 0 14 14 14 10 Zinc-finger double-stranded RNA-binding BHD_1 PF10403.7 MSTRG.32202.1_1 - 4.8e-05 23.0 1.2 11 5.8 0.0 5.5 5 1 0 5 5 5 0 Rad4 beta-hairpin domain 1 BolA PF01722.16 MSTRG.32202.1_1 - 0.00025 21.1 5.4 21 5.4 0.0 5.9 5 2 0 5 5 5 0 BolA-like protein zf-C2HE PF16278.3 MSTRG.32202.1_1 - 0.0012 19.2 2.9 0.0012 19.2 2.9 13.6 3 2 9 12 12 11 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.3 MSTRG.32202.1_1 - 0.0012 18.4 125.6 0.022 14.4 5.4 14.4 16 0 0 16 16 15 8 zinc-finger C2H2-type Zn-ribbon_8 PF09723.8 MSTRG.32202.1_1 - 0.022 14.7 1.2 0.022 14.7 1.2 10.3 4 4 8 13 13 13 0 Zinc ribbon domain C1_1 PF00130.20 MSTRG.32202.1_1 - 0.034 13.9 0.0 0.034 13.9 0.0 10.8 3 3 8 11 11 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MBD PF01429.17 MSTRG.32202.1_1 - 0.038 13.6 0.6 9.9 5.8 0.0 3.0 2 2 1 3 3 3 0 Methyl-CpG binding domain zinc_ribbon_15 PF17032.3 MSTRG.32202.1_1 - 0.06 14.0 1.6 0.06 14.0 1.6 7.8 4 1 2 7 7 6 0 zinc-ribbon family GAGA PF09237.9 MSTRG.32202.1_1 - 0.062 13.0 20.4 1.8 8.3 0.2 6.5 6 1 1 7 7 7 0 GAGA factor BDHCT_assoc PF16204.3 MSTRG.32202.1_1 - 0.23 11.0 3.6 7.1 6.1 0.2 3.3 2 1 1 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein PhoLip_ATPase_N PF16209.3 MSTRG.121852.1_1 - 8.6e-08 31.7 0.1 1.5e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal DUF2238 PF09997.7 MSTRG.121852.1_1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) PetG PF02529.13 MSTRG.144154.1_1 - 0.084 12.6 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 Prenyltrans PF00432.19 MSTRG.144154.1_1 - 8.9 6.0 15.8 1.4 8.6 1.9 3.1 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Prenyltrans PF00432.19 MSTRG.144154.1_3 - 0.3 10.7 15.4 1.2 8.9 4.7 2.3 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Caveolin PF01146.15 MSTRG.144154.1_3 - 4.6 7.1 12.0 7.2 6.4 12.0 1.4 1 1 0 1 1 1 0 Caveolin DUF4321 PF14209.4 MSTRG.36180.1_1 - 0.0099 15.6 1.5 81 3.0 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4321) NBP1 PF08537.8 MSTRG.36180.1_1 - 0.26 10.5 9.2 34 3.6 0.1 4.0 4 0 0 4 4 4 0 Fungal Nap binding protein NBP1 Toxin_20 PF08089.9 MSTRG.36180.1_3 - 0.001 19.0 0.2 84 3.3 0.0 4.6 6 0 0 6 6 6 4 Huwentoxin-II family SH3_9 PF14604.4 MSTRG.74133.1_2 - 1.5e-12 47.0 0.1 3.1e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 MSTRG.74133.1_2 - 1.7e-11 43.4 0.1 2.9e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 MSTRG.74133.1_2 - 5.1e-08 32.4 0.0 6.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.9 MSTRG.74133.1_2 - 0.00022 21.3 0.2 0.00035 20.7 0.2 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain DDE_3 PF13358.4 MSTRG.23420.1_2 - 6.5e-06 25.8 0.1 8.1e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltrn_RNA_3 PF02598.15 MSTRG.117009.1_2 - 0.0042 16.5 0.1 0.0042 16.5 0.1 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase zf-RVT PF13966.4 MSTRG.117009.1_2 - 0.08 13.7 0.6 0.08 13.7 0.6 1.5 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase Peptidase_C14 PF00656.20 MSTRG.99188.1_3 - 2.6e-24 86.4 0.0 2.9e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Caspase domain zf-A20 PF01754.14 MSTRG.7033.1_2 - 9.6e-13 47.7 5.1 1.3e-12 47.3 5.1 1.2 1 0 0 1 1 1 1 A20-like zinc finger HTH_38 PF13936.4 MSTRG.12123.1_1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Filament PF00038.19 MSTRG.22631.1_3 - 9.6e-91 304.5 49.4 1.2e-90 304.2 49.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.10 MSTRG.22631.1_3 - 2.2e-07 30.8 44.7 0.0023 17.8 17.0 3.6 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.9 MSTRG.22631.1_3 - 0.0022 18.1 22.6 0.0022 18.1 22.6 3.6 2 2 1 3 3 3 2 Autophagy protein 16 (ATG16) Rab5-bind PF09311.9 MSTRG.22631.1_3 - 0.0042 16.4 38.6 0.098 11.9 17.8 2.8 1 1 1 2 2 2 2 Rabaptin-like protein Exonuc_VII_L PF02601.13 MSTRG.22631.1_3 - 0.0069 15.9 13.0 0.0069 15.9 13.0 2.4 2 1 0 2 2 2 1 Exonuclease VII, large subunit IncA PF04156.12 MSTRG.22631.1_3 - 0.045 13.4 56.5 0.014 15.1 14.6 3.6 1 1 2 3 3 3 0 IncA protein Spc7 PF08317.9 MSTRG.22631.1_3 - 0.071 11.8 43.6 0.54 8.9 18.4 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.10 MSTRG.22631.1_3 - 0.098 12.6 9.4 0.27 11.1 1.8 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.10 MSTRG.22631.1_3 - 0.13 12.1 17.6 3.2 7.6 2.2 3.6 2 1 1 3 3 3 0 Laminin Domain II Reo_sigmaC PF04582.10 MSTRG.22631.1_3 - 0.22 10.7 14.0 0.95 8.7 1.5 3.2 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DASH_Hsk3 PF08227.9 MSTRG.22631.1_3 - 0.54 10.5 5.9 4.2 7.7 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like CENP-F_leu_zip PF10473.7 MSTRG.22631.1_3 - 0.57 10.1 48.2 3.4 7.6 18.3 3.8 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.9 MSTRG.22631.1_3 - 1.3 8.6 7.8 1.9 8.0 1.9 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.4 MSTRG.22631.1_3 - 2.7 7.1 34.4 1.2 8.3 8.6 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF972 PF06156.11 MSTRG.22631.1_3 - 4 8.0 35.0 2.2 8.8 0.0 5.2 2 2 3 5 5 5 0 Protein of unknown function (DUF972) FlaC_arch PF05377.9 MSTRG.22631.1_3 - 5.2 7.4 14.6 23 5.4 0.2 5.6 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.10 MSTRG.22631.1_3 - 5.4 6.9 23.6 1.7 8.5 2.3 4.3 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.7 MSTRG.22631.1_3 - 6.3 6.0 46.1 0.51 9.6 4.8 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF1843 PF08898.8 MSTRG.22631.1_3 - 10 6.6 9.1 21 5.6 0.2 4.0 2 1 0 3 3 3 0 Domain of unknown function (DUF1843) HECT PF00632.23 MSTRG.140050.1_1 - 1e-25 90.8 0.0 1.2e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF666 PF05006.10 MSTRG.140050.1_1 - 0.019 15.0 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF666) zf-LITAF-like PF10601.7 MSTRG.15254.1_2 - 1.4e-17 63.5 11.1 1.4e-17 63.5 11.1 1.5 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain Haemadin PF09065.8 MSTRG.123097.1_1 - 0.11 12.1 1.1 1.6 8.4 0.2 2.2 2 0 0 2 2 2 0 Haemadin DUF5003 PF16394.3 MSTRG.123097.1_2 - 0.092 11.7 0.8 4.3 6.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5003) Ig_3 PF13927.4 MSTRG.46524.1_2 - 3e-07 30.8 0.1 3.1e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 MSTRG.46524.1_2 - 4.9e-06 26.4 0.0 4.9e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.4 MSTRG.46524.1_2 - 7.8e-05 22.8 0.0 8.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 MSTRG.46524.1_2 - 0.0032 17.4 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 MSTRG.46524.1_2 - 0.049 13.7 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain C1-set PF07654.13 MSTRG.46524.1_2 - 0.15 12.4 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin C1-set domain PNISR PF15996.3 MSTRG.120926.1_2 - 2.7 8.0 35.4 0.44 10.6 18.3 2.6 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR PCM1_C PF15717.3 MSTRG.120926.1_2 - 3.5 6.1 27.9 0.078 11.5 11.9 2.2 2 0 0 2 2 2 0 Pericentriolar material 1 C terminus Pkinase_Tyr PF07714.15 MSTRG.128358.1_1 - 4.9e-08 32.4 0.1 8.6e-08 31.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.23 MSTRG.128358.1_1 - 0.0066 15.7 0.0 0.018 14.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Lamp PF01299.15 MSTRG.128358.1_1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF4381 PF14316.4 MSTRG.128358.1_1 - 0.032 14.4 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.4 MSTRG.128358.1_1 - 0.039 14.6 0.0 0.058 14.1 0.0 1.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.10 MSTRG.128358.1_1 - 0.07 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) UPF0560 PF10577.7 MSTRG.128358.1_1 - 0.11 10.9 0.2 0.14 10.5 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FixQ PF05545.9 MSTRG.128358.1_1 - 0.17 11.7 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ VERL PF11386.6 MSTRG.38918.1_2 - 0.056 13.5 0.1 0.074 13.1 0.1 1.2 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin GluR_Homer-bdg PF10606.7 MSTRG.18115.1_2 - 4.1e-06 26.7 2.8 6.9e-06 26.0 2.8 1.4 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor Tom5 PF10642.7 MSTRG.18115.1_2 - 0.054 13.4 0.6 0.076 12.9 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase P2X_receptor PF00864.17 MSTRG.96423.2_1 - 5.1e-17 61.9 0.0 6.8e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 ATP P2X receptor P2X_receptor PF00864.17 MSTRG.96423.2_3 - 7.3e-17 61.3 0.0 8.5e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 ATP P2X receptor Aldolase_II PF00596.19 MSTRG.38076.1_1 - 3.6e-29 101.9 0.0 3.9e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain E1_FCCH PF16190.3 MSTRG.95128.1_1 - 3.4e-24 84.7 0.1 5e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.3 MSTRG.95128.1_1 - 4.9e-18 64.9 0.1 3e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle RVT_1 PF00078.25 MSTRG.123768.1_2 - 0.0089 15.4 0.0 0.019 14.4 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.4 MSTRG.123768.1_3 - 0.0036 16.9 0.1 0.0051 16.4 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TB PF00683.15 MSTRG.56912.1_2 - 2.6e-08 33.3 10.7 6e-08 32.1 10.7 1.6 1 0 0 1 1 1 1 TB domain DDE_3 PF13358.4 MSTRG.7073.1_2 - 8.8e-05 22.2 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease UPF0203 PF05254.10 MSTRG.7073.1_2 - 0.02 15.0 0.3 0.026 14.7 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) RVT_1 PF00078.25 MSTRG.86390.1_1 - 0.015 14.7 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.105040.1_3 - 0.0014 18.7 0.3 0.0014 18.7 0.3 1.6 2 1 0 2 2 2 1 Transposase EZH2_WD-Binding PF11616.6 MSTRG.32006.1_1 - 2.1e-15 56.4 0.8 3.4e-15 55.7 0.8 1.4 1 0 0 1 1 1 1 WD repeat binding protein EZH2 Pkinase PF00069.23 MSTRG.21875.1_1 - 6.6e-39 133.7 0.1 7.8e-39 133.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.21875.1_1 - 3e-28 98.7 0.0 3.6e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Dynamitin PF04912.12 MSTRG.121199.1_1 - 2e-13 50.3 0.3 2.5e-13 50.0 0.3 1.1 1 0 0 1 1 1 1 Dynamitin DUF4705 PF15788.3 MSTRG.121199.1_1 - 0.098 12.8 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4705) Guanylate_kin PF00625.19 MSTRG.130596.1_3 - 6e-65 218.2 0.0 8.1e-65 217.8 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.4 MSTRG.130596.1_3 - 5.4e-05 23.6 0.0 0.00011 22.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.4 MSTRG.130596.1_3 - 6.9e-05 23.1 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.25 MSTRG.130596.1_3 - 0.00028 21.3 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.14 MSTRG.130596.1_3 - 0.00073 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.4 MSTRG.130596.1_3 - 0.00083 19.4 0.1 0.0035 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.4 MSTRG.130596.1_3 - 0.0012 19.0 0.1 0.0032 17.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.4 MSTRG.130596.1_3 - 0.0032 17.0 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.27 MSTRG.130596.1_3 - 0.0072 16.6 0.2 0.15 12.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.17 MSTRG.130596.1_3 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.21 MSTRG.130596.1_3 - 0.013 15.5 0.1 0.02 14.8 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.20 MSTRG.130596.1_3 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.4 MSTRG.130596.1_3 - 0.024 14.6 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.4 MSTRG.130596.1_3 - 0.028 14.7 0.2 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.4 MSTRG.130596.1_3 - 0.033 13.8 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.4 MSTRG.130596.1_3 - 0.036 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.10 MSTRG.130596.1_3 - 0.041 13.1 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.10 MSTRG.130596.1_3 - 0.049 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.13 MSTRG.130596.1_3 - 0.05 12.4 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TsaE PF02367.15 MSTRG.130596.1_3 - 0.057 13.3 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.12 MSTRG.130596.1_3 - 0.06 12.4 0.0 0.09 11.9 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_7 PF12775.5 MSTRG.130596.1_3 - 0.067 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 AAA_24 PF13479.4 MSTRG.130596.1_3 - 0.078 12.6 0.4 0.66 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain dNK PF01712.17 MSTRG.130596.1_3 - 0.13 11.9 0.4 0.93 9.2 0.1 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.13 MSTRG.130596.1_3 - 0.15 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase DnaJ PF00226.29 MSTRG.113789.2_2 - 1.8e-14 53.5 0.1 2.4e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain DUF3926 PF13080.4 MSTRG.12203.1_2 - 0.027 14.4 0.7 0.062 13.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) CD225 PF04505.10 MSTRG.12203.1_3 - 8.2e-07 28.9 0.0 1.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Interferon-induced transmembrane protein EF1G PF00647.17 MSTRG.111623.1_2 - 0.002 18.1 2.0 0.084 12.8 0.2 2.2 1 1 1 2 2 2 2 Elongation factor 1 gamma, conserved domain LTD PF00932.17 MSTRG.111623.1_2 - 0.77 10.0 5.1 17 5.7 5.1 2.1 1 1 0 1 1 1 0 Lamin Tail Domain zf-RING_6 PF14835.4 MSTRG.111623.1_2 - 2.8 7.7 4.8 1e+02 2.7 0.1 3.4 1 1 3 4 4 4 0 zf-RING of BARD1-type protein V-set PF07686.15 MSTRG.77797.1_1 - 0.004 17.2 0.0 0.0057 16.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain PEN-2 PF10251.7 MSTRG.44348.1_3 - 0.11 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Collagen PF01391.16 MSTRG.13496.1_1 - 3.3e-13 49.0 64.9 1e-07 31.5 28.4 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) RII_binding_1 PF10522.7 MSTRG.13496.1_1 - 0.12 12.4 0.2 14 6.0 0.0 2.4 2 0 0 2 2 2 0 RII binding domain RII_binding_1 PF10522.7 MSTRG.13496.1_2 - 0.1 12.7 0.1 16 5.9 0.0 3.0 2 0 0 2 2 2 0 RII binding domain NECFESHC PF16621.3 MSTRG.99162.1_2 - 1.5 8.7 9.5 29 4.6 1.5 3.5 1 1 3 4 4 4 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 Packaging_FI PF14000.4 MSTRG.127690.1_3 - 0.29 11.5 5.4 0.53 10.6 5.4 1.4 1 1 0 1 1 1 0 DNA packaging protein FI Osteopontin PF00865.16 MSTRG.127690.1_3 - 0.31 10.4 8.5 0.38 10.1 8.5 1.0 1 0 0 1 1 1 0 Osteopontin Exo_endo_phos PF03372.21 MSTRG.55708.1_3 - 8.8e-05 22.6 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4716 PF15837.3 MSTRG.131024.1_1 - 0.049 13.5 0.2 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) SelP_N PF04592.12 MSTRG.122753.1_1 - 2.2 7.5 14.8 2.4 7.4 14.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1619 PF07773.9 MSTRG.98997.1_3 - 0.05 13.4 2.5 0.066 13.0 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) Transposase_mut PF00872.16 MSTRG.33567.2_1 - 0.015 14.0 0.2 0.016 13.9 0.2 1.2 1 0 0 1 1 1 0 Transposase, Mutator family GrpE PF01025.17 MSTRG.33567.2_1 - 0.023 14.2 5.3 0.029 13.9 5.3 1.4 1 1 0 1 1 1 0 GrpE DUF2203 PF09969.7 MSTRG.33567.2_1 - 0.036 14.6 1.2 0.043 14.4 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CcmH PF03918.12 MSTRG.33567.2_1 - 0.083 12.1 0.2 0.093 11.9 0.2 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein RVT_1 PF00078.25 MSTRG.24175.1_3 - 0.015 14.7 0.0 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_1 PF00018.26 MSTRG.122801.1_2 - 0.00014 21.2 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 MSTRG.122801.1_2 - 0.0028 17.2 0.1 0.0049 16.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 MSTRG.122801.1_2 - 0.0045 16.7 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DOCK_N PF16172.3 MSTRG.122801.1_2 - 0.031 13.1 0.1 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 DOCK N-terminus CAF1C_H4-bd PF12265.6 MSTRG.118357.1_1 - 2e-13 50.3 0.7 2.7e-13 49.8 0.7 1.2 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Mito_carr PF00153.25 MSTRG.19851.1_3 - 4.1e-20 71.4 0.3 3.9e-10 39.4 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein STAR_dimer PF16544.3 MSTRG.19851.1_3 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein DUF3338 PF11819.6 MSTRG.53284.1_2 - 1.3e-14 54.2 0.1 1.5e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) zf-Di19 PF05605.10 MSTRG.98385.1_2 - 0.08 13.1 0.6 0.13 12.5 0.6 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.24 MSTRG.98385.1_2 - 0.53 10.7 4.3 1.1 9.7 4.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.98385.1_2 - 0.63 10.9 4.9 1.2 10.0 4.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Med30 PF11315.6 MSTRG.45614.1_2 - 8.9e-65 217.3 3.0 1.5e-64 216.6 3.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 30 UPF0449 PF15136.4 MSTRG.45614.1_2 - 0.0034 17.7 0.3 0.0081 16.5 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 NYD-SP28_assoc PF14775.4 MSTRG.45614.1_2 - 0.71 9.9 5.3 1.5 8.8 5.3 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Lectin_C PF00059.19 MSTRG.46487.1_1 - 0.0058 17.2 0.1 0.0058 17.2 0.1 1.6 2 0 0 2 2 2 1 Lectin C-type domain ZapB PF06005.10 MSTRG.46487.1_1 - 0.52 10.7 4.6 0.97 9.8 4.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB UL45 PF05473.10 MSTRG.46487.1_1 - 0.66 9.5 5.4 0.046 13.2 0.7 1.5 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like HALZ PF02183.16 MSTRG.46487.1_3 - 4.7e-05 23.4 8.3 0.0015 18.6 5.2 2.3 1 1 1 2 2 2 2 Homeobox associated leucine zipper DUF3450 PF11932.6 MSTRG.46487.1_3 - 6.4e-05 22.2 9.0 8.1e-05 21.9 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) APG6 PF04111.10 MSTRG.46487.1_3 - 0.0043 16.4 5.6 0.0055 16.0 5.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Spc24 PF08286.9 MSTRG.46487.1_3 - 0.0043 17.1 6.1 0.0086 16.2 5.6 1.7 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 IFT57 PF10498.7 MSTRG.46487.1_3 - 0.0052 15.7 10.5 0.0069 15.3 10.5 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Spc7 PF08317.9 MSTRG.46487.1_3 - 0.0067 15.2 8.2 0.0082 14.9 8.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein bZIP_1 PF00170.19 MSTRG.46487.1_3 - 0.014 15.4 9.9 0.06 13.3 2.5 2.4 1 1 1 2 2 2 0 bZIP transcription factor GrpE PF01025.17 MSTRG.46487.1_3 - 0.014 14.9 2.3 0.02 14.4 2.3 1.1 1 0 0 1 1 1 0 GrpE Macoilin PF09726.7 MSTRG.46487.1_3 - 0.015 13.8 10.2 0.019 13.4 10.2 1.0 1 0 0 1 1 1 0 Transmembrane protein JIP_LZII PF16471.3 MSTRG.46487.1_3 - 0.018 15.1 6.0 0.034 14.2 6.0 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II ZapB PF06005.10 MSTRG.46487.1_3 - 0.022 15.0 12.0 0.053 13.8 11.9 1.6 1 1 0 1 1 1 0 Cell division protein ZapB Cep57_CLD_2 PF14197.4 MSTRG.46487.1_3 - 0.029 14.3 11.0 0.056 13.4 11.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.7 MSTRG.46487.1_3 - 0.033 14.1 7.7 0.047 13.6 7.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.11 MSTRG.46487.1_3 - 0.036 14.6 3.1 0.054 14.0 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.6 MSTRG.46487.1_3 - 0.036 14.1 8.7 0.052 13.6 8.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF3552 PF12072.6 MSTRG.46487.1_3 - 0.05 12.9 13.4 0.072 12.4 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4472 PF14739.4 MSTRG.46487.1_3 - 0.093 13.3 7.9 0.17 12.5 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) OmpH PF03938.12 MSTRG.46487.1_3 - 0.13 12.1 10.5 0.18 11.7 10.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.12 MSTRG.46487.1_3 - 0.21 11.2 6.8 0.3 10.7 6.8 1.1 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.11 MSTRG.46487.1_3 - 0.23 9.9 4.2 0.28 9.6 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nnf1 PF03980.12 MSTRG.46487.1_3 - 0.24 11.6 9.8 0.4 11.0 9.8 1.3 1 0 0 1 1 1 0 Nnf1 Seryl_tRNA_N PF02403.20 MSTRG.46487.1_3 - 0.25 11.4 5.4 0.42 10.7 5.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.18 MSTRG.46487.1_3 - 0.27 11.1 13.3 0.87 9.5 5.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF4407 PF14362.4 MSTRG.46487.1_3 - 0.31 10.2 8.5 0.44 9.7 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.10 MSTRG.46487.1_3 - 0.38 11.1 6.7 0.57 10.5 6.7 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.13 MSTRG.46487.1_3 - 0.41 10.3 12.5 0.11 12.1 5.6 2.1 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.17 MSTRG.46487.1_3 - 0.48 8.1 3.8 0.6 7.8 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kinetocho_Slk19 PF12709.5 MSTRG.46487.1_3 - 0.81 10.0 8.3 0.69 10.3 6.4 1.7 1 1 1 2 2 2 0 Central kinetochore-associated DUF4337 PF14235.4 MSTRG.46487.1_3 - 4.8 7.1 5.5 6.7 6.7 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Heme_oxygenase PF01126.18 MSTRG.86019.1_2 - 2.2e-77 259.3 0.9 2.5e-77 259.2 0.9 1.0 1 0 0 1 1 1 1 Heme oxygenase HTH_38 PF13936.4 MSTRG.33420.1_3 - 0.00017 21.1 0.1 0.00025 20.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.33420.1_3 - 0.0044 16.6 0.0 0.0067 16.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.16 MSTRG.33420.1_3 - 0.015 15.1 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 'Paired box' domain HTH_28 PF13518.4 MSTRG.33420.1_3 - 0.055 13.5 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4269 PF14091.4 MSTRG.33420.1_3 - 0.15 12.1 0.1 0.2 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Presenilin PF01080.15 MSTRG.123242.1_1 - 3.6 6.1 7.6 3.1 6.3 7.6 1.0 1 0 0 1 1 1 0 Presenilin DUF4798 PF16055.3 MSTRG.123242.1_2 - 5.4 7.2 9.8 6.3 7.0 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) DUF1031 PF06275.9 MSTRG.57098.1_2 - 0.15 12.2 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) CblD PF07434.9 MSTRG.18212.1_3 - 0.12 11.2 0.5 0.14 10.9 0.5 1.0 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator Ank_2 PF12796.5 MSTRG.79091.1_2 - 4.2e-23 81.6 0.9 1.7e-15 57.2 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.4 MSTRG.79091.1_2 - 1.6e-17 63.2 1.9 3.5e-07 30.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.4 MSTRG.79091.1_2 - 1.4e-16 60.5 0.1 2.3e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_2 PF07653.15 MSTRG.79091.1_2 - 5e-14 51.6 0.0 1.1e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 MSTRG.79091.1_2 - 5.7e-14 51.3 0.0 1.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 MSTRG.79091.1_2 - 5.8e-14 51.5 0.0 9.1e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank PF00023.28 MSTRG.79091.1_2 - 9.9e-12 44.6 0.3 0.00037 20.7 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.4 MSTRG.79091.1_2 - 3.2e-08 33.1 0.0 0.84 10.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat DUF3432 PF11914.6 MSTRG.122335.1_1 - 8.2 6.6 17.1 10 6.3 7.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) DUF2094 PF09867.7 MSTRG.104167.1_3 - 0.031 14.2 0.0 0.031 14.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2094) GDPD PF03009.15 MSTRG.91815.1_1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.4 MSTRG.91815.1_1 - 0.11 13.0 0.3 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family VGLL4 PF15245.4 MSTRG.29284.1_2 - 3.5e-55 187.3 0.1 7.9e-55 186.1 0.2 1.4 2 0 0 2 2 2 1 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.12 MSTRG.29284.1_2 - 0.00066 19.2 0.0 0.91 9.2 0.0 2.4 2 0 0 2 2 2 2 Vestigial/Tondu family DUF1891 PF09004.8 MSTRG.141085.1_3 - 0.00024 20.5 0.1 0.0014 18.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1891) Laminin_N PF00055.15 MSTRG.108842.1_3 - 5.1e-22 78.5 0.0 5.1e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) EGF_2 PF07974.11 MSTRG.89266.1_1 - 1.5e-12 47.5 45.5 0.00024 21.3 12.4 3.2 3 0 0 3 3 3 3 EGF-like domain fn3 PF00041.19 MSTRG.89266.1_1 - 6.9e-11 42.2 0.1 8.5e-11 41.9 0.1 1.1 1 0 0 1 1 1 1 Fibronectin type III domain EGF PF00008.25 MSTRG.89266.1_1 - 0.00013 22.0 37.4 0.093 12.9 10.0 3.5 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.5 MSTRG.89266.1_1 - 0.004 17.6 5.4 0.004 17.6 5.4 4.1 4 0 0 4 4 4 2 Human growth factor-like EGF Actin PF00022.17 MSTRG.89266.1_1 - 0.031 12.8 0.0 0.044 12.3 0.0 1.3 1 1 0 1 1 1 0 Actin Laminin_EGF PF00053.22 MSTRG.89266.1_1 - 0.059 13.4 36.4 0.67 10.0 4.3 3.2 2 1 1 3 3 3 0 Laminin EGF domain EB PF01683.16 MSTRG.89266.1_1 - 0.15 12.2 33.3 3.4 7.8 9.3 3.5 1 1 2 3 3 3 0 EB module EGF_alliinase PF04863.11 MSTRG.89266.1_1 - 0.31 11.3 34.6 0.56 10.5 5.8 3.5 1 1 2 3 3 3 0 Alliinase EGF-like domain Myb_DNA-binding PF00249.29 MSTRG.83711.2_3 - 2.8e-05 24.1 0.7 3.7e-05 23.6 0.7 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 MSTRG.83711.2_3 - 0.0018 18.4 0.4 0.0028 17.7 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain OAD_gamma PF04277.11 MSTRG.5791.1_3 - 0.46 11.0 1.9 0.72 10.4 1.9 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TMEM192 PF14802.4 MSTRG.77665.1_2 - 0.087 11.8 0.1 0.097 11.6 0.1 1.0 1 0 0 1 1 1 0 TMEM192 family Lipin_N PF04571.12 MSTRG.121657.1_3 - 5.7e-20 71.1 0.1 6.5e-20 70.9 0.1 1.1 1 0 0 1 1 1 1 lipin, N-terminal conserved region Ribosomal_L7Ae PF01248.24 MSTRG.10550.1_2 - 2.1e-24 84.9 0.1 6.3e-24 83.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Laminin_G_3 PF13385.4 MSTRG.96141.1_1 - 2.3e-13 50.4 0.3 3.4e-13 49.9 0.3 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.15 MSTRG.96141.1_1 - 0.0061 16.1 0.0 0.01 15.4 0.0 1.4 1 1 0 1 1 1 1 Pentaxin family HTH_OrfB_IS605 PF12323.6 MSTRG.63721.1_3 - 0.55 9.6 1.5 1 8.8 1.5 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SH3_2 PF07653.15 MSTRG.1876.1_2 - 3.6e-09 36.0 0.0 7.9e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DXP_reductoisom PF02670.14 MSTRG.1876.1_2 - 3.3 8.3 8.3 0.41 11.2 2.3 2.7 2 1 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase VHP PF02209.17 MSTRG.131741.1_1 - 2.3e-10 40.2 1.2 3.5e-10 39.6 1.2 1.2 1 0 0 1 1 1 1 Villin headpiece domain Gallidermin PF02052.13 MSTRG.131741.1_3 - 0.2 11.9 1.7 0.38 11.0 1.7 1.4 1 0 0 1 1 1 0 Gallidermin DDE_3 PF13358.4 MSTRG.11233.1_2 - 9.6e-10 38.3 0.4 1.2e-09 37.9 0.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease L51_S25_CI-B8 PF05047.14 MSTRG.89779.1_3 - 7.6e-15 54.5 0.0 1.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SAP PF02037.25 MSTRG.137950.1_3 - 1.2e-11 44.0 0.9 1.7e-11 43.4 0.9 1.3 1 0 0 1 1 1 1 SAP domain Hepatitis_core PF00906.18 MSTRG.137950.1_3 - 0.099 12.1 4.1 0.12 11.8 4.1 1.2 1 0 0 1 1 1 0 Hepatitis core antigen SSF PF00474.15 MSTRG.37284.1_2 - 2.2e-10 39.8 2.6 2.5e-10 39.7 2.6 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family HMG_box PF00505.17 MSTRG.135479.1_3 - 0.00013 22.2 0.5 0.00017 21.8 0.0 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box VIR_N PF15912.3 MSTRG.50543.1_1 - 4.7e-26 91.9 0.0 5.5e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Virilizer, N-terminal AF-4 PF05110.11 MSTRG.19390.1_2 - 0.0051 14.9 22.7 0.0067 14.5 22.7 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DNA_pol_phi PF04931.11 MSTRG.19390.1_2 - 0.049 11.6 1.5 0.062 11.3 1.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi SpoIIIAH PF12685.5 MSTRG.19390.1_2 - 0.11 12.2 4.0 0.15 11.7 4.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1510 PF07423.9 MSTRG.19390.1_2 - 0.12 11.6 1.1 0.18 11.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Apt1 PF10351.7 MSTRG.19390.1_2 - 0.13 10.9 6.6 0.17 10.6 6.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.17 MSTRG.19390.1_2 - 0.17 11.7 6.6 0.21 11.3 6.6 1.1 1 0 0 1 1 1 0 SPX domain DUF4614 PF15391.4 MSTRG.19390.1_2 - 0.37 10.6 12.3 0.58 10.0 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.7 MSTRG.19390.1_2 - 0.76 8.1 8.2 0.99 7.7 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4692 PF15763.3 MSTRG.19390.1_2 - 0.78 10.1 12.5 14 6.0 9.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4692) Period_C PF12114.6 MSTRG.19390.1_2 - 0.8 9.1 18.5 1.2 8.6 18.5 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RAP1 PF07218.9 MSTRG.19390.1_2 - 0.86 7.7 17.9 1.2 7.2 17.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC106 PF15794.3 MSTRG.19390.1_2 - 2.8 7.5 9.2 4.5 6.8 9.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF1635 PF07795.9 MSTRG.19390.1_2 - 3.5 7.4 8.4 5.3 6.8 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Peroxin-3 PF04882.10 MSTRG.19390.1_2 - 3.5 6.4 8.2 4.4 6.0 8.2 1.1 1 0 0 1 1 1 0 Peroxin-3 PAP1 PF08601.8 MSTRG.19390.1_2 - 4 6.9 14.7 5.1 6.6 14.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Secretin_N_2 PF07655.11 MSTRG.19390.1_2 - 4 7.9 16.1 8 7.0 16.1 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.23211.1_2 - 0.0012 19.0 0.1 0.0016 18.5 0.1 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.4 MSTRG.23211.1_3 - 0.042 13.5 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain UT PF03253.12 MSTRG.49010.1_2 - 2.8e-102 341.7 35.1 3.6e-102 341.3 35.1 1.1 1 0 0 1 1 1 1 Urea transporter LRR_8 PF13855.4 MSTRG.73067.1_3 - 2.3e-21 75.2 24.0 4.4e-08 32.6 5.0 4.7 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.5 MSTRG.73067.1_3 - 1.7e-11 43.9 21.5 0.00011 22.3 1.5 5.2 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 MSTRG.73067.1_3 - 9.2e-09 34.4 13.7 0.22 12.0 0.1 6.9 5 2 1 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.4 MSTRG.73067.1_3 - 3e-05 23.6 20.8 0.87 9.7 0.3 7.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_9 PF14580.4 MSTRG.73067.1_3 - 0.0047 16.3 0.4 0.0097 15.3 0.2 1.7 1 1 0 1 1 1 1 Leucine-rich repeat Tn7_TnsC_Int PF11426.6 MSTRG.73067.1_3 - 0.037 14.1 0.4 0.18 11.9 0.3 2.3 2 0 0 2 2 2 0 Tn7 transposition regulator TnsC NifU_N PF01592.14 MSTRG.27409.1_3 - 2.4e-55 186.0 0.1 3.5e-55 185.5 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain CD34_antigen PF06365.10 MSTRG.37633.1_3 - 1.1e-24 87.1 0.1 2.7e-24 85.8 0.0 1.5 1 1 1 2 2 2 1 CD34/Podocalyxin family Ribosom_S12_S23 PF00164.23 MSTRG.33335.1_2 - 1.3e-24 86.2 0.2 1.5e-24 86.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Torsin PF06309.9 MSTRG.48837.1_2 - 6e-32 110.3 0.5 6.3e-32 110.2 0.5 1.0 1 0 0 1 1 1 1 Torsin Sigma54_activat PF00158.24 MSTRG.48837.1_2 - 0.053 13.1 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain PH_9 PF15410.4 MSTRG.54331.1_2 - 9.5e-22 77.5 1.0 1.8e-21 76.6 1.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.27 MSTRG.54331.1_2 - 8.7e-17 61.4 0.7 1.6e-16 60.6 0.7 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 MSTRG.54331.1_2 - 0.0013 18.9 1.4 0.0036 17.5 1.4 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.3 MSTRG.54331.1_2 - 0.048 13.4 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_Tyr PF07714.15 MSTRG.77493.1_3 - 2.5e-30 105.5 0.0 3.9e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 MSTRG.77493.1_3 - 1.5e-19 70.3 0.0 2.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.4 MSTRG.77493.1_3 - 5.7e-15 55.3 1.0 8.3e-06 26.1 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.4 MSTRG.77493.1_3 - 6.8e-15 54.8 0.5 6e-10 39.1 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.28 MSTRG.77493.1_3 - 4.3e-14 52.1 0.9 7.7e-06 26.0 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.5 MSTRG.77493.1_3 - 8.2e-14 51.8 0.0 2.5e-13 50.3 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.4 MSTRG.77493.1_3 - 1.7e-13 49.3 0.0 0.00035 20.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat DIM PF08194.10 MSTRG.31346.1_2 - 4.2 7.5 7.0 18 5.5 2.7 2.3 2 0 0 2 2 2 0 DIM protein fn1 PF00039.16 MSTRG.17813.1_1 - 2.1e-08 34.1 13.9 4.1e-08 33.1 13.9 1.5 1 0 0 1 1 1 1 Fibronectin type I domain IPK PF03770.14 MSTRG.102935.1_1 - 2.9e-18 66.3 0.1 8.6e-18 64.8 0.1 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase WD40 PF00400.30 MSTRG.100392.1_3 - 5.2e-11 42.8 0.3 3.7e-06 27.4 0.1 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.100392.1_3 - 1.5e-06 28.3 0.2 8.2e-05 22.7 0.1 1.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 MSTRG.100392.1_3 - 0.014 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.10 MSTRG.100392.1_3 - 0.028 12.3 0.1 0.19 9.5 0.1 1.8 1 1 0 1 1 1 0 IKI3 family DDE_3 PF13358.4 MSTRG.17605.1_2 - 3.2e-10 39.8 0.3 4.7e-10 39.3 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Thyroglobulin_1 PF00086.16 MSTRG.62643.1_1 - 1.2e-17 63.2 0.7 2.8e-17 62.0 0.7 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Sod_Cu PF00080.18 MSTRG.2501.1_3 - 3.2e-40 137.4 0.0 5.6e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.24 MSTRG.2501.1_3 - 1.3e-11 44.6 0.5 2.4e-11 43.8 0.5 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF177 PF02620.15 MSTRG.2501.1_3 - 0.17 11.9 0.7 4.4 7.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized ACR, COG1399 LRRNT PF01462.16 MSTRG.108265.1_3 - 2.3 7.9 7.1 1.9 8.1 1.8 2.9 2 1 1 3 3 3 0 Leucine rich repeat N-terminal domain CSTF_C PF14304.4 MSTRG.105819.1_3 - 2e-20 71.9 8.6 2.9e-20 71.4 8.6 1.2 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal PDZ PF00595.22 MSTRG.812.1_3 - 3.3e-14 52.9 0.1 4.6e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 MSTRG.812.1_3 - 0.00098 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain COX14 PF14880.4 MSTRG.1918.1_3 - 6.9e-09 35.3 0.3 1e-08 34.7 0.3 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Mito_carr PF00153.25 MSTRG.28131.1_1 - 0.00036 20.3 0.1 0.00049 19.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein HTH_32 PF13565.4 MSTRG.130040.1_3 - 0.004 17.6 0.6 0.0053 17.2 0.6 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Shisa PF13908.4 MSTRG.118742.1_3 - 0.00061 19.9 0.0 0.00075 19.7 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator IncA PF04156.12 MSTRG.118742.1_3 - 0.0028 17.4 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 IncA protein FAM163 PF15069.4 MSTRG.118742.1_3 - 0.0045 17.3 0.3 0.006 16.9 0.3 1.2 1 0 0 1 1 1 1 FAM163 family Sushi PF00084.18 MSTRG.118742.1_3 - 0.036 14.6 0.5 0.036 14.6 0.5 2.0 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Bap31 PF05529.10 MSTRG.118742.1_3 - 0.041 13.4 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like EphA2_TM PF14575.4 MSTRG.118742.1_3 - 0.2 12.3 0.4 0.36 11.5 0.4 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EGF_CA PF07645.13 MSTRG.69458.1_2 - 9.2e-07 28.8 9.4 1.2e-06 28.5 9.4 1.2 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.25 MSTRG.69458.1_2 - 8.9e-06 25.8 10.6 1.2e-05 25.4 10.6 1.2 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.5 MSTRG.69458.1_2 - 0.0026 18.2 9.0 0.0049 17.4 9.0 1.5 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_3 PF12947.5 MSTRG.69458.1_2 - 0.023 14.7 7.0 0.033 14.2 7.0 1.2 1 0 0 1 1 1 0 EGF domain RabGAP-TBC PF00566.16 MSTRG.26049.1_3 - 4e-28 98.4 1.1 4.5e-28 98.2 1.1 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4249 PF14054.4 MSTRG.26049.1_3 - 0.022 14.2 0.1 0.028 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) DDE_3 PF13358.4 MSTRG.41731.1_2 - 0.0003 20.4 0.1 0.00041 20.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BPL_C PF02237.15 MSTRG.33655.1_2 - 0.039 13.7 0.1 0.061 13.1 0.1 1.2 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Tox-GHH PF15636.4 MSTRG.33655.1_2 - 0.046 13.5 0.9 0.056 13.2 0.9 1.1 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin VWC PF00093.16 MSTRG.66026.1_3 - 7.6e-18 64.4 33.4 9.5e-11 41.7 14.8 3.7 4 0 0 4 4 4 2 von Willebrand factor type C domain TILa PF12714.5 MSTRG.66026.1_3 - 8.5e-05 22.3 23.1 0.0097 15.7 5.7 3.1 2 0 0 2 2 2 2 TILa domain CFC PF09443.8 MSTRG.66026.1_3 - 0.0028 17.4 4.0 0.0028 17.4 4.0 4.0 4 0 0 4 4 4 2 Cripto_Frl-1_Cryptic (CFC) Amnionless PF14828.4 MSTRG.66026.1_3 - 0.0048 15.7 14.2 0.0048 15.7 14.2 2.7 2 1 1 3 3 3 2 Amnionless DUF4939 PF16297.3 MSTRG.5781.1_3 - 1.5e-09 37.6 0.0 3.3e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4939) Baculo_PP31 PF05311.9 MSTRG.52495.1_3 - 0.073 12.4 1.6 2.9 7.2 0.2 2.4 2 1 1 3 3 3 0 Baculovirus 33KDa late protein (PP31) Ig_3 PF13927.4 MSTRG.82109.1_1 - 1.1e-14 54.7 0.0 1.2e-13 51.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.14 MSTRG.82109.1_1 - 6.9e-13 48.3 0.0 1.6e-12 47.2 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.4 MSTRG.82109.1_1 - 8.2e-08 32.4 0.0 8.8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 MSTRG.82109.1_1 - 5.4e-07 29.6 0.0 3.9e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_5 PF16681.3 MSTRG.82109.1_1 - 0.0055 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.15 MSTRG.82109.1_1 - 0.14 12.2 0.1 11 6.1 0.0 2.6 2 1 1 3 3 3 0 Immunoglobulin V-set domain C2-set_2 PF08205.10 MSTRG.82109.1_1 - 0.15 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain C2 PF00168.28 MSTRG.118290.1_2 - 3e-08 33.8 0.1 4.5e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 C2 domain bZIP_1 PF00170.19 MSTRG.135332.1_2 - 4.9e-15 55.2 16.5 6.5e-15 54.8 16.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 MSTRG.135332.1_2 - 6.3e-10 38.9 13.4 9e-10 38.4 13.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 MSTRG.135332.1_2 - 1.6e-06 28.4 8.4 2.6e-06 27.7 8.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF4404 PF14357.4 MSTRG.135332.1_2 - 0.011 16.3 0.8 0.021 15.3 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) HAUS6_N PF14661.4 MSTRG.135332.1_2 - 0.027 13.9 2.0 0.032 13.7 2.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus LPP20 PF02169.14 MSTRG.135332.1_2 - 0.029 14.6 0.1 0.048 13.9 0.1 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein DivIC PF04977.13 MSTRG.135332.1_2 - 2.1 8.0 6.2 0.41 10.3 1.7 1.9 1 1 1 2 2 2 0 Septum formation initiator Integrin_beta PF00362.16 MSTRG.89011.1_3 - 3.6e-73 246.2 0.0 4e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Integrin beta chain VWA domain YIF1 PF03878.13 MSTRG.140299.1_1 - 2.8e-84 282.2 4.8 3.7e-84 281.9 4.8 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.15 MSTRG.140299.1_1 - 1.9e-13 50.4 8.1 1.9e-13 50.4 8.1 2.1 3 0 0 3 3 3 1 Yip1 domain AAA PF00004.27 MSTRG.122444.1_2 - 1.5e-41 141.8 0.0 3e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.12 MSTRG.122444.1_2 - 1.2e-05 25.2 0.8 4.8e-05 23.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.10 MSTRG.122444.1_2 - 3.2e-05 23.2 0.1 0.0002 20.5 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.4 MSTRG.122444.1_2 - 3.3e-05 24.2 0.2 0.0049 17.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.12 MSTRG.122444.1_2 - 0.00033 20.7 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.4 MSTRG.122444.1_2 - 0.0015 18.6 0.3 0.11 12.6 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.4 MSTRG.122444.1_2 - 0.0047 16.9 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.11 MSTRG.122444.1_2 - 0.0047 16.0 0.0 0.0095 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.14 MSTRG.122444.1_2 - 0.0085 15.4 0.1 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.19 MSTRG.122444.1_2 - 0.0086 15.3 0.1 0.021 14.1 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.15 MSTRG.122444.1_2 - 0.023 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.4 MSTRG.122444.1_2 - 0.03 13.9 0.5 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3713 PF12506.6 MSTRG.122444.1_2 - 0.043 14.0 1.1 0.27 11.4 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) AAA_24 PF13479.4 MSTRG.122444.1_2 - 0.054 13.1 0.1 0.17 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain ATPase PF06745.11 MSTRG.122444.1_2 - 0.055 12.7 0.5 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.24 MSTRG.122444.1_2 - 0.058 13.0 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain JIP_LZII PF16471.3 MSTRG.122444.1_2 - 0.83 9.7 6.6 1.8 8.7 6.6 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Anoctamin PF04547.10 MSTRG.89686.1_3 - 3.5e-13 49.0 0.0 4.2e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Surp PF01805.18 MSTRG.97446.1_2 - 5.1e-15 55.1 0.3 7.2e-15 54.6 0.3 1.2 1 0 0 1 1 1 1 Surp module Occludin_ELL PF07303.11 MSTRG.14126.1_1 - 1.1e-32 112.5 8.7 1.1e-32 112.5 8.7 1.5 2 0 0 2 2 2 1 Occludin homology domain DUF812 PF05667.9 MSTRG.14126.1_1 - 0.018 13.8 2.1 0.027 13.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) EGF_CA PF07645.13 MSTRG.131348.1_3 - 0.057 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain zf-Nse PF11789.6 MSTRG.61419.1_1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Stathmin PF00836.17 MSTRG.125020.1_2 - 7.6e-31 106.8 31.2 8.3e-31 106.6 31.2 1.0 1 0 0 1 1 1 1 Stathmin family HTH_8 PF02954.17 MSTRG.125020.1_2 - 0.041 13.6 0.8 0.041 13.6 0.8 2.2 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family DUF4638 PF15472.4 MSTRG.125020.1_2 - 0.54 9.9 12.7 0.6 9.8 12.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CcdA PF07362.10 MSTRG.125020.1_2 - 2 8.8 13.6 0.13 12.6 5.0 2.2 1 1 1 2 2 2 0 Post-segregation antitoxin CcdA NINJA_B PF16136.3 MSTRG.125020.1_2 - 5.2 7.3 12.9 7 6.9 12.9 1.2 1 0 0 1 1 1 0 Putative nuclear localisation signal McyA_C PF12593.6 MSTRG.125020.1_3 - 0.053 13.2 0.1 0.092 12.4 0.1 1.4 1 0 0 1 1 1 0 Microcystin synthetase C terminal SCIFF PF13165.4 MSTRG.63104.1_1 - 0.026 14.3 0.9 0.041 13.7 0.9 1.3 1 0 0 1 1 1 0 Six-cysteine peptide SCIFF DEAD PF00270.27 MSTRG.94914.1_3 - 0.0041 16.8 0.0 0.0049 16.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ER PF01133.15 MSTRG.61922.1_1 - 9.1e-45 150.5 0.2 1.2e-44 150.1 0.2 1.2 1 0 0 1 1 1 1 Enhancer of rudimentary Glyco_transf_8 PF01501.18 MSTRG.80125.1_1 - 0.13 11.6 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 8 NHase_alpha PF02979.14 MSTRG.110809.1_3 - 0.11 11.7 0.2 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain Neuropeptide_S PF14993.4 MSTRG.87827.1_1 - 0.078 12.7 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Neuropeptide S precursor protein PH PF00169.27 MSTRG.72708.1_3 - 1.3e-17 64.1 0.2 1.8e-17 63.6 0.2 1.2 1 0 0 1 1 1 1 PH domain Pkinase PF00069.23 MSTRG.72708.1_3 - 6.4e-05 22.3 0.1 8.7e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain PH_11 PF15413.4 MSTRG.72708.1_3 - 0.0035 17.6 0.3 0.0086 16.4 0.3 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain HSR PF03172.11 MSTRG.143960.1_2 - 1.5e-23 82.6 0.1 2.1e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 HSR domain CARD PF00619.19 MSTRG.143960.1_2 - 0.025 14.5 0.1 0.056 13.3 0.1 1.7 1 0 0 1 1 1 0 Caspase recruitment domain FDC-SP PF15215.4 MSTRG.133813.1_1 - 6.3 7.3 12.3 9 6.8 0.2 3.8 4 0 0 4 4 4 0 Follicular dendritic cell secreted peptide FDC-SP PF15215.4 MSTRG.133813.1_2 - 0.46 10.9 11.4 0.5 10.8 0.7 2.9 3 0 0 3 3 3 0 Follicular dendritic cell secreted peptide DUF2101 PF09874.7 MSTRG.133813.1_3 - 0.87 9.1 3.9 1.1 8.8 3.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) DUF2721 PF11026.6 MSTRG.133813.1_3 - 1.8 8.3 11.0 0.043 13.6 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) FDC-SP PF15215.4 MSTRG.133813.1_3 - 6.8 7.2 8.5 10 6.6 0.4 2.3 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide Solute_trans_a PF03619.14 MSTRG.50455.1_3 - 2.5e-10 40.2 0.1 3e-10 40.0 0.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CbeA_antitoxin PF06154.9 MSTRG.41414.1_3 - 0.12 12.8 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A SAM_1 PF00536.28 MSTRG.140365.1_2 - 7.3e-19 67.8 0.3 9.1e-19 67.5 0.3 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 MSTRG.140365.1_2 - 2.1e-11 43.6 0.1 2.6e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FliMN_C PF01052.18 MSTRG.140365.1_2 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term TGF_beta PF00019.18 MSTRG.63950.1_3 - 4.7e-35 120.5 0.8 6.9e-35 120.0 0.8 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 MSTRG.63950.1_3 - 5.3e-20 72.1 0.1 7.2e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 TGF-beta propeptide Peptidase_C2 PF00648.19 MSTRG.7401.1_2 - 1.3e-23 83.3 0.4 1.4e-23 83.2 0.4 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease HTH_38 PF13936.4 MSTRG.66132.1_3 - 0.00041 20.0 0.1 0.00065 19.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.66132.1_3 - 0.0043 17.1 0.7 0.015 15.4 0.1 2.1 2 1 0 2 2 2 1 Transposase GcrA PF07750.9 MSTRG.66132.1_3 - 0.022 15.1 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator HTH_23 PF13384.4 MSTRG.66132.1_3 - 0.081 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.66132.1_3 - 0.09 13.3 0.0 0.3 11.6 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain PMP22_Claudin PF00822.18 MSTRG.58596.1_1 - 5e-27 94.7 9.8 7.3e-27 94.1 9.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 MSTRG.58596.1_1 - 7.7e-05 22.4 12.9 0.0004 20.1 12.2 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.8 MSTRG.58596.1_1 - 0.97 9.1 4.6 2.4 7.8 1.1 2.6 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Laminin_EGF PF00053.22 MSTRG.108366.1_2 - 1.9e-13 50.2 24.9 1.9e-08 34.2 7.4 2.1 2 0 0 2 2 2 2 Laminin EGF domain DUF4408 PF14364.4 MSTRG.119421.1_3 - 0.033 13.8 1.2 0.11 12.1 1.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) V_ATPase_I PF01496.17 MSTRG.13518.1_1 - 5.9e-94 315.4 0.0 6.5e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Peptidase_M13 PF01431.19 MSTRG.53728.1_1 - 2.5e-27 95.7 1.1 2.7e-27 95.6 1.1 1.0 1 0 0 1 1 1 1 Peptidase family M13 HTH_Tnp_Tc3_2 PF01498.16 MSTRG.69154.1_1 - 2.2e-07 30.9 0.4 4.3e-07 30.0 0.4 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.4 MSTRG.69154.1_1 - 6.7e-07 29.0 0.1 1.2e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CSTF1_dimer PF16699.3 MSTRG.96399.1_3 - 0.086 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain COX7a PF02238.13 MSTRG.25382.1_2 - 0.038 14.3 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII Peptidase_S24 PF00717.21 MSTRG.25382.1_2 - 0.051 13.4 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase S24-like LRR_6 PF13516.4 MSTRG.63870.1_2 - 5.1e-14 50.9 3.2 7e-06 25.6 0.0 2.9 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.5 MSTRG.63870.1_2 - 0.00045 20.4 2.5 0.023 15.0 0.3 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 MSTRG.63870.1_2 - 0.0048 16.5 2.0 0.044 13.4 0.2 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.31 MSTRG.63870.1_2 - 0.017 15.4 5.7 0.56 10.8 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat BAP PF06639.9 MSTRG.63870.1_2 - 0.072 13.2 1.3 0.18 12.0 1.3 1.6 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) Tom5 PF10642.7 MSTRG.57962.1_1 - 0.22 11.4 0.7 1.8 8.5 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase ubiquitin PF00240.21 MSTRG.22619.1_2 - 2.4e-18 65.5 0.6 3.8e-18 64.9 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 MSTRG.22619.1_2 - 8.6e-07 28.6 1.1 1.4e-06 27.9 1.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.8 MSTRG.22619.1_2 - 0.0013 19.3 0.0 0.0027 18.2 0.0 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD_2 PF13881.4 MSTRG.22619.1_2 - 0.0049 16.8 0.1 0.011 15.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 MSTRG.22619.1_2 - 0.02 15.3 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UN_NPL4 PF11543.6 MSTRG.22619.1_2 - 0.12 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 XPC-binding PF09280.9 MSTRG.22619.1_2 - 0.81 9.4 25.8 1.6 8.4 7.7 3.7 1 1 2 3 3 3 0 XPC-binding domain p450 PF00067.20 MSTRG.39448.1_3 - 1.4e-37 129.4 0.0 1.7e-36 125.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF4523 PF15023.4 MSTRG.39448.1_3 - 0.075 12.7 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) CTD PF12815.5 MSTRG.102642.1_3 - 1.6 9.2 9.4 19 5.8 9.4 2.1 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Mg_trans_NIPA PF05653.12 MSTRG.3740.1_1 - 4.1e-05 22.7 1.3 5.7e-05 22.2 1.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Mg_trans_NIPA PF05653.12 MSTRG.3740.1_2 - 4.5e-77 258.9 11.2 6.1e-77 258.5 11.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.18 MSTRG.3740.1_2 - 1.8e-07 31.2 5.3 1.8e-07 31.2 5.3 2.8 2 1 0 2 2 2 1 EamA-like transporter family ALG3 PF05208.11 MSTRG.133616.1_2 - 0.004 16.6 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 ALG3 protein WD40 PF00400.30 MSTRG.55924.1_3 - 7.8e-07 29.6 3.9 0.018 15.8 0.9 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.55924.1_3 - 0.00062 19.9 0.0 0.0039 17.3 0.0 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 MSTRG.55924.1_3 - 0.0021 16.6 0.2 0.36 9.2 0.0 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.3 MSTRG.55924.1_3 - 0.078 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Tup_N PF08581.8 MSTRG.128019.1_1 - 0.012 15.7 0.7 0.31 11.2 0.3 2.1 1 1 1 2 2 2 0 Tup N-terminal DUF1031 PF06275.9 MSTRG.77810.1_3 - 0.2 11.8 1.5 0.3 11.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DUF2113 PF09886.7 MSTRG.44854.1_1 - 0.034 13.4 0.0 0.042 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.109468.1_3 - 4.6e-07 29.9 1.1 1.1e-06 28.6 0.4 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.4 MSTRG.109468.1_3 - 6.7e-06 25.6 0.0 1.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.109468.1_3 - 0.00015 22.2 0.9 0.0019 18.7 1.5 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.4 MSTRG.109468.1_3 - 0.013 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.4 MSTRG.109468.1_3 - 0.076 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix An_peroxidase PF03098.13 MSTRG.75946.1_1 - 3.5e-37 128.0 0.2 3.7e-37 128.0 0.2 1.0 1 0 0 1 1 1 1 Animal haem peroxidase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.138454.1_3 - 2e-12 47.0 1.0 2e-12 47.0 1.0 1.7 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.4 MSTRG.138454.1_3 - 0.0073 16.8 0.3 0.012 16.1 0.3 1.4 1 0 0 1 1 1 1 Homeodomain-like domain zf-H2C2_2 PF13465.4 MSTRG.53546.1_3 - 1.2e-16 60.2 35.9 9.9e-10 38.3 1.8 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.53546.1_3 - 8.5e-07 29.2 33.1 0.00091 19.7 2.9 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.24 MSTRG.53546.1_3 - 2.2e-06 27.6 35.3 0.00044 20.4 3.3 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 MSTRG.53546.1_3 - 0.0073 16.1 1.9 0.0073 16.1 1.9 4.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.53546.1_3 - 0.0088 16.2 0.5 0.0088 16.2 0.5 4.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.4 MSTRG.53546.1_3 - 0.11 12.6 12.9 14 5.9 0.4 4.5 4 0 0 4 4 4 0 zinc-ribbon zf-C2HE PF16278.3 MSTRG.53546.1_3 - 1.8 9.0 24.4 0.28 11.5 2.9 4.3 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_10 PF10058.7 MSTRG.53546.1_3 - 2.2 7.9 9.1 35 4.1 2.8 3.4 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-LYAR PF08790.9 MSTRG.53546.1_3 - 6.4 6.6 18.3 1.8 8.4 0.1 4.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Elf1 PF05129.11 MSTRG.53546.1_3 - 7.6 6.5 18.7 3.8 7.5 7.0 2.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HTH_Tnp_Tc3_2 PF01498.16 MSTRG.68589.1_1 - 1.1e-09 38.2 1.3 1.4e-09 38.0 1.3 1.1 1 0 0 1 1 1 1 Transposase DUF3915 PF13054.4 MSTRG.37572.1_3 - 0.3 11.0 2.3 0.34 10.7 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DDE_3 PF13358.4 MSTRG.53982.1_2 - 0.00015 21.4 0.3 0.00021 20.9 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_C PF12025.6 MSTRG.118873.1_3 - 0.095 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Phage protein C HEPN PF05168.12 MSTRG.95730.1_2 - 4.4e-08 33.1 0.1 1.9e-07 31.1 0.1 2.2 1 0 0 1 1 1 1 HEPN domain DnaJ PF00226.29 MSTRG.95730.1_2 - 0.00044 20.2 0.1 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.105225.1_1 - 1.3e-14 54.1 0.8 1.5e-14 53.9 0.8 1.1 1 0 0 1 1 1 1 Transposase Y_phosphatase PF00102.25 MSTRG.46214.1_2 - 1.6e-22 80.1 0.1 2.1e-22 79.7 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.18 MSTRG.46214.1_2 - 0.0021 17.7 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain OTT_1508_deam PF14441.4 MSTRG.130469.1_3 - 0.03 14.1 0.4 0.03 14.1 0.4 1.6 2 0 0 2 2 2 0 OTT_1508-like deaminase DDE_3 PF13358.4 MSTRG.108391.1_2 - 0.00047 19.8 0.6 0.00066 19.3 0.6 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Tcell_CD4_C PF12104.6 MSTRG.95842.1_1 - 0.0027 17.5 0.1 0.0068 16.2 0.1 1.7 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region TFIIA PF03153.11 MSTRG.29108.1_2 - 2.1e-53 182.7 27.9 2.1e-53 182.7 27.9 2.1 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF4820 PF16091.3 MSTRG.29108.1_2 - 0.1 11.8 2.9 0.16 11.2 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDC45 PF02724.12 MSTRG.29108.1_2 - 0.12 10.5 5.9 0.13 10.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.8 MSTRG.29108.1_2 - 0.18 11.0 11.5 0.24 10.6 11.5 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.10 MSTRG.29108.1_2 - 0.34 9.0 12.3 0.41 8.7 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.10 MSTRG.29108.1_2 - 0.47 9.7 11.6 0.62 9.3 11.6 1.2 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.12 MSTRG.29108.1_2 - 0.7 9.5 6.7 1.2 8.8 6.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.11 MSTRG.29108.1_2 - 3.6 5.5 18.8 4.8 5.0 18.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.6 MSTRG.29108.1_2 - 9.5 5.1 10.2 14 4.6 10.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2650 PF10853.6 MSTRG.32769.1_1 - 2.3 7.9 11.6 61 3.4 0.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2650) Ndr PF03096.12 MSTRG.113956.1_2 - 1.4e-21 76.3 0.0 1.7e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Ndr family Lysis_col PF02402.14 MSTRG.6048.1_3 - 0.11 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Lysis protein DUF4202 PF13875.4 MSTRG.39241.1_3 - 0.46 10.2 4.6 67 3.2 0.0 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4202) DDE_3 PF13358.4 MSTRG.120253.1_2 - 0.0034 17.0 0.1 0.0037 16.9 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FinO_N PF12602.6 MSTRG.34208.1_3 - 0.24 11.6 8.3 59 3.9 0.6 5.0 2 1 2 4 4 4 0 Fertility inhibition protein N terminal Bacteriocin_IIc PF10439.7 MSTRG.103285.1_1 - 0.069 13.1 11.2 0.12 12.4 11.2 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF2798 PF11391.6 MSTRG.103285.1_1 - 0.25 11.3 10.3 48 4.0 10.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) DUF2953 PF11167.6 MSTRG.103285.1_1 - 4.1 7.4 7.2 9.1 6.3 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2953) PT-VENN PF04829.11 MSTRG.103285.1_1 - 4.7 7.2 9.7 25 4.9 9.7 2.2 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Pkinase_Tyr PF07714.15 MSTRG.93959.1_3 - 1.2e-35 123.0 0.2 1.4e-35 122.7 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 MSTRG.93959.1_3 - 9.2e-21 74.2 0.2 1.3e-20 73.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.4 MSTRG.93959.1_3 - 0.023 13.9 0.1 0.025 13.7 0.1 1.1 1 0 0 1 1 1 0 Kinase-like HTH_Tnp_Tc3_2 PF01498.16 MSTRG.52588.1_3 - 0.025 14.7 0.6 0.044 13.9 0.6 1.4 1 0 0 1 1 1 0 Transposase SH3_1 PF00018.26 MSTRG.110965.1_3 - 1.2e-13 50.3 1.6 1.6e-13 49.9 1.6 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 MSTRG.110965.1_3 - 7.3e-11 41.5 0.0 1.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 MSTRG.110965.1_3 - 2.9e-10 39.7 0.5 4.1e-10 39.2 0.5 1.2 1 0 0 1 1 1 1 Variant SH3 domain Cadherin PF00028.15 MSTRG.47473.1_3 - 1.5e-06 28.4 0.0 4.3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Cadherin domain Pcc1 PF09341.8 MSTRG.47473.1_3 - 0.074 13.1 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 Transcription factor Pcc1 RRM_1 PF00076.20 MSTRG.103292.1_3 - 0.001 18.7 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2537 PF10801.6 MSTRG.36721.1_1 - 0.027 14.6 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) AMP-binding PF00501.26 MSTRG.74645.1_1 - 5e-09 35.1 0.0 5.4e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF972 PF06156.11 MSTRG.70540.1_3 - 0.0094 16.4 7.9 0.0094 16.4 7.9 7.4 3 2 4 7 7 7 1 Protein of unknown function (DUF972) ADIP PF11559.6 MSTRG.70540.1_3 - 0.01 15.8 10.3 0.01 15.8 10.3 7.2 2 1 5 7 7 7 0 Afadin- and alpha -actinin-Binding DASH_Hsk3 PF08227.9 MSTRG.70540.1_3 - 0.45 10.8 9.6 0.87 9.9 0.3 4.2 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Phage_P2_GpE PF06528.10 MSTRG.109814.1_1 - 0.12 11.8 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 Phage P2 GpE Peptidase_C69 PF03577.13 MSTRG.55952.1_2 - 7.9e-12 44.9 0.5 1.5e-11 44.0 0.5 1.3 1 1 0 1 1 1 1 Peptidase family C69 Antimicrobial14 PF08109.9 MSTRG.76034.1_1 - 0.073 13.0 0.2 0.56 10.2 0.1 2.0 2 0 0 2 2 2 0 Lactocin 705 family Antimicrobial14 PF08109.9 MSTRG.76034.1_2 - 0.56 10.2 0.1 0.56 10.2 0.1 2.3 4 0 0 4 4 4 0 Lactocin 705 family ADK_lid PF05191.12 MSTRG.76034.1_3 - 0.086 12.8 0.8 14 5.7 0.8 3.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid Biotin_carb_N PF00289.20 MSTRG.141752.1_3 - 3.5e-07 30.6 0.6 6.1e-07 29.8 0.2 1.6 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain API5 PF05918.9 MSTRG.132693.1_1 - 1.6e-30 106.3 0.0 2e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) ArfGap PF01412.16 MSTRG.24666.2_1 - 3.4e-41 139.8 0.6 6.3e-41 138.9 0.6 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RMI1_N PF08585.10 MSTRG.24666.2_1 - 0.11 12.1 2.6 0.15 11.7 2.4 1.4 1 1 0 1 1 1 0 RecQ mediated genome instability protein DIOX_N PF14226.4 MSTRG.24666.2_1 - 0.87 10.2 3.6 1.1 9.9 1.4 1.9 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal Afi1 PF07792.10 MSTRG.24666.2_1 - 1.7 9.0 5.0 0.26 11.6 0.3 1.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TUDOR PF00567.22 MSTRG.37450.1_1 - 1.8e-25 89.2 0.0 4.6e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 Tudor domain 7tm_1 PF00001.19 MSTRG.40388.1_1 - 7.3e-14 51.5 2.2 7.6e-14 51.4 2.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BTAD PF03704.15 MSTRG.40388.1_3 - 0.049 13.9 0.0 0.051 13.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Gelsolin PF00626.20 MSTRG.140597.1_2 - 1.8e-57 191.0 0.0 1.4e-17 63.2 0.0 5.0 5 0 0 5 5 5 4 Gelsolin repeat zf-C2H2 PF00096.24 MSTRG.58786.1_2 - 1.4e-11 44.1 33.1 6.2e-05 23.1 4.1 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 MSTRG.58786.1_2 - 5.6e-08 32.8 15.4 1.8e-06 28.0 4.9 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 MSTRG.58786.1_2 - 3.3e-06 27.3 24.5 0.013 16.1 3.5 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.5 MSTRG.58786.1_2 - 4.7 7.6 11.1 0.53 10.6 1.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Sina PF03145.14 MSTRG.58786.1_2 - 8.1 6.2 9.2 15 5.4 9.2 1.4 1 0 0 1 1 1 0 Seven in absentia protein family DUF972 PF06156.11 MSTRG.137012.1_2 - 0.08 13.4 0.4 0.12 12.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V-set PF07686.15 MSTRG.100370.1_2 - 3.6e-06 27.0 0.0 4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain End_beta_barrel PF12195.6 MSTRG.100370.1_2 - 0.088 12.6 0.5 0.34 10.8 0.0 2.0 2 1 1 3 3 3 0 Beta barrel domain of bacteriophage endosialidase Pkinase_Tyr PF07714.15 MSTRG.119342.1_2 - 3.2e-74 249.4 0.0 5.9e-74 248.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.23 MSTRG.119342.1_2 - 4.4e-45 154.0 0.0 5.7e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.19 MSTRG.119342.1_2 - 7.2e-26 90.2 0.1 1.8e-11 44.1 0.1 3.0 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.4 MSTRG.119342.1_2 - 1.1e-19 70.9 0.0 2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain STE2 PF02116.13 MSTRG.119342.1_2 - 0.0002 20.7 0.0 0.00031 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Pur_ac_phosph_N PF16656.3 MSTRG.119342.1_2 - 0.00025 21.4 0.0 0.028 14.9 0.0 2.9 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.8 MSTRG.119342.1_2 - 0.00032 20.8 0.0 0.013 15.7 0.0 2.7 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Kdo PF06293.12 MSTRG.119342.1_2 - 0.00078 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.14 MSTRG.119342.1_2 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.20 MSTRG.119342.1_2 - 0.047 13.2 0.1 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Lamp PF01299.15 MSTRG.119342.1_2 - 0.68 9.3 2.7 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) CARMIL_C PF16000.3 MSTRG.43451.1_3 - 1.2e-11 44.7 2.2 1.4e-11 44.5 2.2 1.0 1 0 0 1 1 1 1 CARMIL C-terminus MYT1 PF08474.9 MSTRG.43451.1_3 - 0.069 12.9 0.6 0.077 12.7 0.6 1.1 1 0 0 1 1 1 0 Myelin transcription factor 1 DUF1043 PF06295.10 MSTRG.43451.1_3 - 0.096 12.5 2.0 0.12 12.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FCSD-flav_bind PF09242.9 MSTRG.129175.1_1 - 0.06 13.6 0.3 0.089 13.0 0.3 1.2 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding RRM_1 PF00076.20 MSTRG.24023.1_2 - 5.1e-12 45.3 0.0 7.2e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ureide_permease PF07168.9 MSTRG.112875.1_2 - 0.35 9.5 2.9 0.43 9.2 2.9 1.1 1 0 0 1 1 1 0 Ureide permease ICAM_N PF03921.12 MSTRG.114278.1_3 - 7.5e-06 25.4 0.1 1e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Intercellular adhesion molecule (ICAM), N-terminal domain SLIDE PF09111.8 MSTRG.114297.1_1 - 0.048 13.5 0.7 2.6 8.0 0.2 2.7 1 1 1 2 2 2 0 SLIDE Cornifin PF02389.13 MSTRG.114297.1_3 - 0.00051 20.1 0.1 0.00061 19.9 0.1 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family PH PF00169.27 MSTRG.114896.1_1 - 2.4e-14 53.6 0.0 3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 MSTRG.114896.1_1 - 1e-06 29.0 0.3 3.6e-06 27.2 0.3 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.4 MSTRG.114896.1_1 - 4.6e-05 23.5 0.0 6.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.4 MSTRG.114896.1_1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.43610.1_2 - 1.7e-09 37.6 1.3 2.2e-09 37.3 1.3 1.1 1 0 0 1 1 1 1 Transposase RVT_1 PF00078.25 MSTRG.98250.1_3 - 3.6e-10 39.6 0.0 5.4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sulfotransfer_1 PF00685.25 MSTRG.86476.1_2 - 1.3e-61 208.4 0.7 1.5e-61 208.1 0.7 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 MSTRG.86476.1_2 - 1.9e-05 25.1 0.1 3.1e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family FERM_N PF09379.8 MSTRG.81327.1_3 - 4.3e-08 32.8 0.1 1.5e-07 31.1 0.1 1.7 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.16 MSTRG.81327.1_3 - 3.2e-06 27.4 0.1 5.7e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 FERM central domain UPF0193 PF05250.9 MSTRG.81327.1_3 - 0.064 12.9 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) RVT_1 PF00078.25 MSTRG.130778.1_2 - 1e-10 41.4 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UcrQ PF02939.14 MSTRG.130778.1_2 - 0.087 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 UcrQ family Retrotrans_gag PF03732.15 MSTRG.130778.1_3 - 0.039 14.1 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein HTH_23 PF13384.4 MSTRG.63544.1_1 - 6.6e-07 28.8 0.6 1.2e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.63544.1_1 - 6.7e-06 26.5 1.0 0.0013 19.2 0.9 2.2 1 1 1 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.4 MSTRG.63544.1_1 - 1e-05 25.3 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.16 MSTRG.63544.1_1 - 0.0007 19.7 4.5 0.0012 19.0 1.7 2.2 2 0 0 2 2 2 1 Transposase PAX PF00292.16 MSTRG.63544.1_1 - 0.0042 16.9 0.1 0.006 16.4 0.1 1.1 1 0 0 1 1 1 1 'Paired box' domain Sigma70_r4 PF04545.14 MSTRG.63544.1_1 - 0.0073 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.10 MSTRG.63544.1_1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.4 MSTRG.63544.1_1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.4 MSTRG.63544.1_1 - 0.11 12.0 1.1 2.8 7.4 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding zf-Dof PF02701.13 MSTRG.63544.1_1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Dof domain, zinc finger CLPTM1 PF05602.10 MSTRG.20033.1_1 - 4e-151 503.7 0.2 5.2e-151 503.4 0.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.12 MSTRG.20033.1_1 - 0.011 15.4 1.8 0.58 9.8 0.1 2.9 2 0 0 2 2 2 0 PQ loop repeat DUF1097 PF06496.9 MSTRG.20033.1_1 - 0.077 13.0 5.1 0.046 13.7 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) DUF2079 PF09852.7 MSTRG.65628.1_1 - 0.00072 18.4 0.9 0.00083 18.2 0.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) SDP_N PF12278.6 MSTRG.18331.1_2 - 1.3 8.6 10.5 2.4 7.7 10.5 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal EF-hand_2 PF09068.9 MSTRG.32682.1_3 - 3.3e-34 117.5 0.8 4.8e-34 117.0 0.8 1.2 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.9 MSTRG.32682.1_3 - 5.6e-25 87.4 0.1 3.5e-24 84.9 0.0 2.1 2 1 0 2 2 2 1 EF-hand DUF3544 PF12064.6 MSTRG.107613.1_2 - 1e-47 163.0 0.4 1.1e-47 162.9 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3544) Cep57_CLD PF14073.4 MSTRG.107613.1_2 - 0.012 15.5 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 CHZ PF09649.8 MSTRG.90366.1_2 - 0.038 13.3 0.4 0.055 12.8 0.4 1.2 1 0 0 1 1 1 0 Histone chaperone domain CHZ START PF01852.17 MSTRG.126441.1_1 - 3.3e-06 26.5 0.0 4.2e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 START domain Stn1_C PF12659.5 MSTRG.122309.1_2 - 0.056 13.3 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH HTH_Tnp_Tc3_2 PF01498.16 MSTRG.54348.1_3 - 6e-17 61.5 2.0 9.1e-17 60.9 2.0 1.2 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.4 MSTRG.54348.1_3 - 0.003 18.0 0.4 0.0057 17.1 0.1 1.5 1 1 1 2 2 2 1 Homeodomain-like domain PAC1 PF16094.3 MSTRG.76293.1_2 - 4.3e-23 81.8 0.9 4.7e-23 81.6 0.9 1.0 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF3435 PF11917.6 MSTRG.21612.1_2 - 0.023 13.5 0.1 0.023 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF3361 PF11841.6 MSTRG.21765.1_2 - 3.4e-38 130.9 3.3 4.5e-38 130.5 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) SIL1 PF16782.3 MSTRG.21765.1_2 - 0.00024 20.3 0.9 0.00028 20.1 0.9 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 PemK_toxin PF02452.15 MSTRG.119914.1_2 - 0.0015 18.7 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system Deltaretro_Tax PF05599.9 MSTRG.16613.1_3 - 0.056 13.8 0.9 0.056 13.8 0.9 1.5 2 0 0 2 2 2 0 Deltaretrovirus Tax protein DDE_3 PF13358.4 MSTRG.71479.1_3 - 0.0014 18.2 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease THRAP3_BCLAF1 PF15440.4 MSTRG.31427.2_2 - 9.6e-66 223.0 8.4 1.1e-65 222.9 8.4 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family Trp_repressor PF01371.17 MSTRG.31427.2_2 - 0.002 18.1 0.1 0.003 17.5 0.1 1.3 1 1 0 1 1 1 1 Trp repressor protein Methyltrn_RNA_2 PF04013.10 MSTRG.31427.2_2 - 0.022 14.3 0.1 0.052 13.1 0.0 1.6 2 0 0 2 2 2 0 Putative SAM-dependent RNA methyltransferase Neur_chan_memb PF02932.14 MSTRG.6926.1_3 - 3.2e-32 112.4 2.9 7.9e-32 111.1 2.8 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2 PF00096.24 MSTRG.118898.1_1 - 1.6e-08 34.4 3.0 6e-05 23.1 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.118898.1_1 - 1.6e-08 34.5 4.3 0.00037 21.0 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.3 MSTRG.118898.1_1 - 4.2e-07 29.5 3.1 0.00098 18.7 0.2 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2HE PF16278.3 MSTRG.118898.1_1 - 3e-06 27.5 3.9 0.0022 18.3 0.3 2.4 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.6 MSTRG.118898.1_1 - 0.0014 18.7 1.9 0.096 12.9 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 MSTRG.118898.1_1 - 0.0016 18.2 2.7 0.056 13.3 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-UBP PF02148.17 MSTRG.118898.1_1 - 0.0024 18.0 2.4 0.0067 16.6 2.4 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_8 PF15909.3 MSTRG.118898.1_1 - 0.0033 17.5 0.2 0.0075 16.4 0.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon C1_1 PF00130.20 MSTRG.118898.1_1 - 0.0055 16.4 1.9 0.5 10.2 0.4 2.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.8 MSTRG.118898.1_1 - 0.013 15.0 1.2 0.25 11.0 0.2 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_15 PF17032.3 MSTRG.118898.1_1 - 0.042 14.5 0.1 0.09 13.4 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon family zf-C2H2_2 PF12756.5 MSTRG.118898.1_1 - 0.053 13.7 6.6 0.52 10.5 0.9 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.12 MSTRG.118898.1_1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-BED PF02892.13 MSTRG.118898.1_1 - 0.11 12.4 3.7 0.26 11.2 1.3 2.4 2 0 0 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.8 MSTRG.118898.1_1 - 0.2 11.6 2.1 1.6 8.8 2.2 2.3 1 1 1 2 2 2 0 Zinc ribbon domain ACT_7 PF13840.4 MSTRG.85754.1_2 - 2.8e-13 49.3 0.2 5e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 ACT domain Exo_endo_phos PF03372.21 MSTRG.139356.1_2 - 0.15 12.1 1.2 0.16 12.1 1.2 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PVL_ORF50 PF07768.9 MSTRG.139356.1_2 - 0.61 10.3 10.0 0.74 10.0 10.0 1.1 1 0 0 1 1 1 0 PVL ORF-50-like family DUF2058 PF09831.7 MSTRG.139356.1_2 - 3.8 7.4 17.2 4.5 7.2 17.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) I_LWEQ PF01608.15 MSTRG.139356.1_2 - 7 6.7 12.7 9 6.4 12.7 1.2 1 0 0 1 1 1 0 I/LWEQ domain RPE65 PF03055.13 MSTRG.74128.1_3 - 9.1e-10 38.2 0.1 9.4e-10 38.1 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2513 PF10711.7 MSTRG.74128.1_3 - 0.15 12.2 0.1 0.34 11.1 0.1 1.7 1 1 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_23 PF13384.4 MSTRG.78339.1_2 - 4e-06 26.3 0.3 5.6e-06 25.9 0.3 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.4 MSTRG.78339.1_2 - 0.00087 19.2 0.5 0.0012 18.7 0.5 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.4 MSTRG.78339.1_2 - 0.022 14.6 0.6 0.029 14.3 0.6 1.2 1 0 0 1 1 1 0 Winged helix-turn helix SUFU_C PF12470.6 MSTRG.58125.2_2 - 0.025 14.4 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain SUFU_C PF12470.6 MSTRG.58125.2_3 - 2e-28 99.7 0.2 2.3e-28 99.5 0.2 1.1 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain IMPDH PF00478.23 MSTRG.93339.1_3 - 0.017 14.0 0.0 0.017 14.0 0.0 1.0 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Peptidase_S8_N PF16361.3 MSTRG.93339.1_3 - 0.02 15.2 0.0 0.023 15.0 0.0 1.0 1 0 0 1 1 1 0 N-terminal of Subtilase family dCache_3 PF14827.4 MSTRG.93339.1_3 - 0.14 11.6 0.0 0.15 11.5 0.0 1.0 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase HTH_38 PF13936.4 MSTRG.130700.1_1 - 0.0035 17.0 0.2 0.0059 16.2 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.130700.1_1 - 0.073 13.2 0.4 0.22 11.7 0.0 2.1 2 1 0 2 2 2 0 Transposase HTH_40 PF14493.4 MSTRG.130700.1_1 - 0.087 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S13_N PF08069.10 MSTRG.130700.1_1 - 0.14 12.1 3.4 0.95 9.4 0.1 3.0 2 1 1 3 3 3 0 Ribosomal S13/S15 N-terminal domain MH1 PF03165.14 MSTRG.50726.1_3 - 0.0004 20.4 0.1 0.0006 19.9 0.1 1.3 1 0 0 1 1 1 1 MH1 domain NAGLU PF05089.10 MSTRG.50726.1_3 - 0.016 14.1 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain GreA_GreB PF01272.17 MSTRG.50726.1_3 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term DUF4713 PF15831.3 MSTRG.87520.1_3 - 1.4e-08 34.9 0.4 1.7e-08 34.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) Caveolin PF01146.15 MSTRG.87520.1_3 - 0.041 13.7 0.1 0.045 13.6 0.1 1.1 1 0 0 1 1 1 0 Caveolin Hexokinase_1 PF00349.19 MSTRG.36831.1_2 - 1.5e-17 64.1 0.0 1.6e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Hexokinase HTH_23 PF13384.4 MSTRG.119729.1_1 - 2.5e-05 23.8 0.0 5.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.119729.1_1 - 0.00052 20.5 0.9 0.004 17.6 1.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.119729.1_1 - 0.0015 18.6 0.3 0.0068 16.5 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.4 MSTRG.119729.1_1 - 0.0056 16.5 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.4 MSTRG.119729.1_1 - 0.0073 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.13 MSTRG.119729.1_1 - 0.029 14.3 0.5 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase PMM PF03332.11 MSTRG.119864.1_3 - 1.2e-104 348.8 0.6 1.5e-104 348.5 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.10 MSTRG.119864.1_3 - 2.5e-07 30.5 0.0 7.5e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RVT_1 PF00078.25 MSTRG.32245.1_3 - 0.0045 16.4 0.1 0.02 14.2 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4524 PF15025.4 MSTRG.32245.1_3 - 0.044 13.4 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) DUF1970 PF09301.8 MSTRG.3524.1_2 - 0.1 12.7 1.3 0.15 12.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) STAT_alpha PF01017.18 MSTRG.57981.1_3 - 5.5e-53 179.3 7.8 5.5e-53 179.3 7.8 2.5 2 1 0 2 2 2 1 STAT protein, all-alpha domain STAT_int PF02865.15 MSTRG.57981.1_3 - 5.1e-35 120.5 5.2 5.1e-35 120.5 5.2 3.0 2 1 1 3 3 3 1 STAT protein, protein interaction domain Reprolysin_5 PF13688.4 MSTRG.57981.1_3 - 0.0025 17.9 5.7 0.015 15.3 0.5 2.1 1 1 1 2 2 2 1 Metallo-peptidase family M12 PAP_central PF04928.15 MSTRG.57981.1_3 - 0.059 12.2 4.9 0.58 8.9 4.7 2.3 1 1 0 1 1 1 0 Poly(A) polymerase central domain MutS_III PF05192.16 MSTRG.57981.1_3 - 0.11 12.6 2.1 0.21 11.7 2.1 1.5 1 0 0 1 1 1 0 MutS domain III DUF1664 PF07889.10 MSTRG.57981.1_3 - 0.41 10.5 4.9 5.9 6.8 0.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) F_actin_bind PF08919.8 MSTRG.57981.1_3 - 4.5 7.3 12.1 1.7 8.6 2.4 3.1 1 1 1 2 2 2 0 F-actin binding BLOC1_2 PF10046.7 MSTRG.57981.1_3 - 4.6 7.5 11.2 9.5 6.5 0.1 3.3 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF349 PF03993.10 MSTRG.57981.1_3 - 5.4 7.3 7.0 2.6 8.3 0.4 3.1 4 0 0 4 4 4 0 Domain of Unknown Function (DUF349) zf-C2H2 PF00096.24 MSTRG.14501.1_1 - 1.4e-26 91.3 46.5 1.1e-05 25.5 1.6 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.14501.1_1 - 3.4e-19 67.7 42.1 0.001 19.5 0.9 7.7 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.4 MSTRG.14501.1_1 - 1.3e-12 47.4 46.7 8.4e-05 22.7 2.7 7.3 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_jaz PF12171.6 MSTRG.14501.1_1 - 2.9e-11 43.2 34.4 0.039 14.1 0.9 7.6 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 MSTRG.14501.1_1 - 3.9e-10 39.6 36.7 0.031 14.5 1.2 7.4 8 0 0 8 8 7 4 Zinc-finger of C2H2 type DUF2256 PF10013.7 MSTRG.14501.1_1 - 0.00025 21.0 26.1 0.98 9.5 0.4 6.5 6 0 0 6 6 6 3 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_6 PF13912.4 MSTRG.14501.1_1 - 0.1 12.4 33.0 2.2 8.2 0.7 6.9 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_2 PF12756.5 MSTRG.14501.1_1 - 0.12 12.6 31.2 0.7 10.1 0.5 6.5 4 3 3 7 7 7 0 C2H2 type zinc-finger (2 copies) YhfH PF14149.4 MSTRG.14501.1_1 - 0.33 10.8 12.5 12 5.8 0.0 4.6 4 0 0 4 4 4 0 YhfH-like protein zf-LYAR PF08790.9 MSTRG.14501.1_1 - 0.44 10.4 0.1 0.44 10.4 0.1 6.0 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger BolA PF01722.16 MSTRG.14501.1_1 - 3.2 8.0 9.4 0.63 10.2 0.1 3.2 3 0 0 3 3 3 0 BolA-like protein IMPDH PF00478.23 MSTRG.140565.2_3 - 8e-20 71.0 0.2 9.4e-20 70.8 0.2 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Redoxin PF08534.8 MSTRG.61332.1_3 - 0.13 11.8 0.1 0.15 11.6 0.1 1.0 1 0 0 1 1 1 0 Redoxin Laminin_G_2 PF02210.22 MSTRG.40196.1_2 - 2.1e-05 25.0 0.0 2.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.21 MSTRG.40196.1_2 - 0.011 15.8 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Laminin G domain EF-hand_4 PF12763.5 MSTRG.101350.1_2 - 2.9e-18 65.6 0.0 3.9e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.30 MSTRG.101350.1_2 - 0.0026 17.0 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.4 MSTRG.101350.1_2 - 0.044 14.1 0.0 0.063 13.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.4 MSTRG.101350.1_2 - 0.14 11.7 0.3 0.25 10.8 0.3 1.3 1 0 0 1 1 1 0 EF hand HLH PF00010.24 MSTRG.103906.1_1 - 6.9e-17 61.0 0.4 1.6e-16 59.9 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain zf-CXXC PF02008.18 MSTRG.112691.1_1 - 1.5e-16 60.0 17.4 2.4e-16 59.3 17.4 1.4 1 0 0 1 1 1 1 CXXC zinc finger domain DUF4597 PF15366.4 MSTRG.21810.1_1 - 0.32 10.6 8.1 0.21 11.2 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) PH_9 PF15410.4 MSTRG.68182.1_2 - 8.6e-14 51.8 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.27 MSTRG.68182.1_2 - 4.7e-12 46.2 0.1 7e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 MSTRG.68182.1_2 - 2.3e-07 31.0 0.1 3.3e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.3 MSTRG.68182.1_2 - 0.048 13.4 0.0 0.059 13.1 0.0 1.3 1 1 0 1 1 1 0 Pleckstrin homology domain TOPRIM_C PF16898.3 MSTRG.68182.1_2 - 0.067 13.3 0.2 0.11 12.6 0.2 1.6 1 1 0 1 1 1 0 C-terminal associated domain of TOPRIM DUF2537 PF10801.6 MSTRG.14836.1_2 - 0.21 11.7 1.3 0.32 11.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) Pex24p PF06398.9 MSTRG.3904.1_2 - 0.0086 15.0 0.1 0.0094 14.8 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HABP4_PAI-RBP1 PF04774.13 MSTRG.102581.1_3 - 0.1 13.3 3.1 0.15 12.7 0.1 2.1 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family HemolysinCabind PF00353.17 MSTRG.7120.1_2 - 0.06 13.8 9.4 4 8.2 1.2 4.0 1 1 5 6 6 6 0 Haemolysin-type calcium-binding repeat (2 copies) DUF2917 PF11142.6 MSTRG.7120.1_2 - 1.9 7.8 25.4 8.9 5.7 3.1 5.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2917) FGF-BP1 PF06473.10 MSTRG.125808.1_3 - 0.098 12.4 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) PHD PF00628.27 MSTRG.82535.1_2 - 5.8e-10 38.8 1.2 7.9e-10 38.3 1.2 1.1 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.4 MSTRG.82535.1_2 - 0.0026 17.1 0.4 0.0043 16.4 0.4 1.3 1 0 0 1 1 1 1 PHD-finger SH3_9 PF14604.4 MSTRG.98785.1_3 - 2.8e-14 52.5 0.0 4.5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 MSTRG.98785.1_3 - 5.5e-14 51.4 0.0 7.6e-14 50.9 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 MSTRG.98785.1_3 - 1.4e-09 37.3 0.0 2.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain 3-dmu-9_3-mt PF06983.11 MSTRG.51245.1_2 - 0.11 13.0 0.0 0.19 12.2 0.0 1.5 1 1 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase CH PF00307.29 MSTRG.81949.1_2 - 1.5e-08 34.6 0.0 1.8e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.6 MSTRG.81949.1_2 - 0.011 15.4 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain Ribophorin_II PF05817.12 MSTRG.39086.1_3 - 4.9e-25 88.0 0.1 5.3e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II RbsD_FucU PF05025.11 MSTRG.39086.1_3 - 0.065 13.5 0.1 0.3 11.4 0.1 1.8 1 1 1 2 2 2 0 RbsD / FucU transport protein family Sen15 PF09631.8 MSTRG.39086.1_3 - 0.14 12.3 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Sen15 protein SAM_1 PF00536.28 MSTRG.136604.1_1 - 0.0013 19.0 0.2 0.0039 17.5 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 MSTRG.136604.1_1 - 0.04 13.9 0.1 0.16 12.0 0.1 2.1 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TPR_19 PF14559.4 MSTRG.136604.1_1 - 0.11 12.9 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat PRORP PF16953.3 MSTRG.42523.1_1 - 7.7e-50 169.5 0.1 8.7e-50 169.4 0.1 1.0 1 0 0 1 1 1 1 Protein-only RNase P EGF_2 PF07974.11 MSTRG.20323.1_2 - 0.077 13.3 9.1 0.14 12.4 9.1 1.4 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.25 MSTRG.20323.1_2 - 0.19 11.9 7.1 0.19 11.9 5.2 1.9 2 0 0 2 2 2 0 EGF-like domain ADAM_spacer1 PF05986.12 MSTRG.116430.1_1 - 2.3e-20 72.6 0.0 3.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.17 MSTRG.116430.1_1 - 2.9e-07 30.5 31.6 3.8e-05 23.7 5.9 3.1 3 0 0 3 3 3 2 Thrombospondin type 1 domain Yae1_N PF09811.7 MSTRG.40958.1_2 - 0.0029 17.1 2.4 0.0054 16.3 2.4 1.5 1 1 0 1 1 1 1 Essential protein Yae1, N terminal RTBV_P46 PF06216.9 MSTRG.121725.1_1 - 0.00014 20.7 0.3 0.00019 20.3 0.3 1.1 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein Fez1 PF06818.13 MSTRG.121725.1_1 - 0.0019 18.6 6.6 0.0031 17.9 6.6 1.3 1 1 0 1 1 1 1 Fez1 TMF_DNA_bd PF12329.6 MSTRG.121725.1_1 - 0.0026 17.6 9.5 0.0026 17.6 9.5 3.1 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding IFT57 PF10498.7 MSTRG.121725.1_1 - 0.0032 16.4 6.9 0.0046 15.9 6.9 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF3138 PF11336.6 MSTRG.121725.1_1 - 0.0066 15.0 0.8 0.0084 14.6 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) Baculo_PEP_C PF04513.10 MSTRG.121725.1_1 - 0.01 15.8 0.4 0.01 15.8 0.4 1.5 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.10 MSTRG.121725.1_1 - 0.011 15.0 1.7 0.018 14.4 1.2 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ABC_tran_CTD PF16326.3 MSTRG.121725.1_1 - 0.012 15.7 16.0 0.015 15.4 7.1 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.13 MSTRG.121725.1_1 - 0.014 15.0 13.4 0.17 11.5 0.1 3.0 2 1 1 3 3 3 0 Septum formation initiator FliD_C PF07195.10 MSTRG.121725.1_1 - 0.02 14.2 2.4 0.02 14.2 2.4 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus IL28A PF15177.4 MSTRG.121725.1_1 - 0.027 14.2 2.0 0.051 13.3 2.0 1.4 1 0 0 1 1 1 0 Interleukin-28A DUF4407 PF14362.4 MSTRG.121725.1_1 - 0.027 13.7 5.1 0.044 13.0 4.6 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4172 PF13776.4 MSTRG.121725.1_1 - 0.029 14.6 0.7 0.21 11.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) TSNAXIP1_N PF15739.3 MSTRG.121725.1_1 - 0.033 14.5 1.3 0.033 14.5 1.3 3.1 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus Syntaxin-6_N PF09177.9 MSTRG.121725.1_1 - 0.045 14.2 5.5 0.1 13.1 5.5 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Phage_GPO PF05929.9 MSTRG.121725.1_1 - 0.047 13.2 5.4 0.015 14.8 2.9 1.4 2 0 0 2 2 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fmp27_WPPW PF10359.7 MSTRG.121725.1_1 - 0.051 12.3 1.2 0.051 12.3 1.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cob_adeno_trans PF01923.16 MSTRG.121725.1_1 - 0.056 13.5 2.6 0.041 13.9 1.2 1.4 2 0 0 2 2 1 0 Cobalamin adenosyltransferase DUF1451 PF07295.9 MSTRG.121725.1_1 - 0.061 13.2 2.2 0.1 12.5 2.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF885 PF05960.9 MSTRG.121725.1_1 - 0.094 12.2 1.9 0.14 11.6 1.9 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Nsp1_C PF05064.11 MSTRG.121725.1_1 - 0.13 12.0 5.6 0.17 11.6 4.9 1.6 1 1 0 1 1 1 0 Nsp1-like C-terminal region TMF_TATA_bd PF12325.6 MSTRG.121725.1_1 - 0.17 12.0 18.6 1.3 9.1 1.3 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.9 MSTRG.121725.1_1 - 0.19 9.5 2.5 0.23 9.2 2.5 1.1 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.6 MSTRG.121725.1_1 - 0.26 8.6 9.2 0.37 8.1 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.4 MSTRG.121725.1_1 - 0.32 9.5 5.9 0.45 9.0 5.9 1.2 1 0 0 1 1 1 0 AAA domain TSC22 PF01166.16 MSTRG.121725.1_1 - 0.33 11.1 5.7 7.5 6.8 0.1 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family ApoLp-III PF07464.9 MSTRG.121725.1_1 - 0.41 10.6 10.0 1 9.3 10.0 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Rootletin PF15035.4 MSTRG.121725.1_1 - 0.45 10.4 13.4 0.82 9.6 0.5 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HAUS6_N PF14661.4 MSTRG.121725.1_1 - 0.61 9.5 8.7 0.81 9.1 8.7 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4140 PF13600.4 MSTRG.121725.1_1 - 0.74 10.2 12.4 18 5.7 10.1 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Exonuc_VII_L PF02601.13 MSTRG.121725.1_1 - 0.83 9.0 8.5 1.4 8.3 8.4 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Tho2 PF11262.6 MSTRG.121725.1_1 - 0.91 8.5 6.6 0.087 11.9 2.0 1.6 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Prefoldin PF02996.15 MSTRG.121725.1_1 - 1.1 9.0 12.7 0.31 10.8 6.7 2.5 1 1 1 2 2 2 0 Prefoldin subunit DUF4618 PF15397.4 MSTRG.121725.1_1 - 1.3 8.3 14.5 1.1 8.5 10.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2968 PF11180.6 MSTRG.121725.1_1 - 1.3 8.5 11.2 0.091 12.3 5.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) ZapB PF06005.10 MSTRG.121725.1_1 - 1.4 9.3 21.5 1.5 9.2 10.3 3.0 2 1 1 3 3 3 0 Cell division protein ZapB LUC7 PF03194.13 MSTRG.121725.1_1 - 1.5 8.3 7.8 1.8 8.0 7.9 1.3 1 1 0 1 1 1 0 LUC7 N_terminus bZIP_2 PF07716.13 MSTRG.121725.1_1 - 1.6 8.7 12.6 1.9 8.5 3.6 2.9 2 0 0 2 2 2 0 Basic region leucine zipper DUF16 PF01519.14 MSTRG.121725.1_1 - 2.1 8.8 14.5 3.7 8.0 7.9 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF4337 PF14235.4 MSTRG.121725.1_1 - 2.4 8.1 6.3 0.66 9.9 3.3 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) 5_nucleotid PF05761.12 MSTRG.121725.1_1 - 2.6 6.7 5.3 3.8 6.2 5.3 1.2 1 0 0 1 1 1 0 5' nucleotidase family EzrA PF06160.10 MSTRG.121725.1_1 - 2.7 5.9 13.7 0.33 9.0 9.7 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA SYCE1 PF15233.4 MSTRG.121725.1_1 - 2.8 7.9 23.3 6.1 6.8 10.8 3.0 2 1 1 3 3 3 0 Synaptonemal complex central element protein 1 Cauli_AT PF03233.11 MSTRG.121725.1_1 - 3.2 7.5 8.7 1.9 8.3 6.6 1.7 2 0 0 2 2 1 0 Aphid transmission protein NPV_P10 PF05531.10 MSTRG.121725.1_1 - 3.2 8.1 8.6 7.9 6.9 4.3 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.11 MSTRG.121725.1_1 - 3.3 8.2 11.4 9.6 6.8 4.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) HMMR_N PF15905.3 MSTRG.121725.1_1 - 3.5 6.9 20.2 0.19 11.0 15.1 1.5 2 0 0 2 2 1 0 Hyaluronan mediated motility receptor N-terminal CREPT PF16566.3 MSTRG.121725.1_1 - 3.9 7.5 13.7 2.4 8.2 8.0 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TPR_MLP1_2 PF07926.10 MSTRG.121725.1_1 - 4.1 7.4 19.4 0.28 11.1 10.9 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.13 MSTRG.121725.1_1 - 4.3 7.0 12.9 2.3 7.9 9.4 2.0 2 0 0 2 2 2 0 Mnd1 family Med9 PF07544.11 MSTRG.121725.1_1 - 4.4 7.3 18.6 0.81 9.7 9.4 3.1 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 MCU PF04678.11 MSTRG.121725.1_1 - 5.2 7.0 7.9 1.8 8.6 5.2 1.6 2 0 0 2 2 1 0 Mitochondrial calcium uniporter SlyX PF04102.10 MSTRG.121725.1_1 - 5.2 7.6 16.3 0.49 10.9 5.5 3.2 2 1 1 3 3 3 0 SlyX DUF342 PF03961.11 MSTRG.121725.1_1 - 6.2 5.2 12.3 1.7 7.0 9.5 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.8 MSTRG.121725.1_1 - 8 6.5 13.9 0.87 9.6 8.9 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.11 MSTRG.121725.1_1 - 8.3 5.4 7.5 15 4.6 7.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF1031 PF06275.9 MSTRG.73924.1_1 - 0.021 14.9 0.1 0.029 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Adaptin_N PF01602.18 MSTRG.13284.2_1 - 9.7e-55 186.0 0.2 1.1e-54 185.8 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.5 MSTRG.13284.2_1 - 7.5e-05 22.7 0.5 0.0002 21.3 0.0 1.9 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 zf-H2C2_2 PF13465.4 MSTRG.125092.1_3 - 5.5e-06 26.5 8.9 0.0024 18.1 4.3 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.125092.1_3 - 0.0012 19.0 10.1 0.02 15.2 2.6 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.125092.1_3 - 0.01 16.5 7.1 0.08 13.7 1.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger DUF1178 PF06676.9 MSTRG.125092.1_3 - 0.017 15.3 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) zf-met PF12874.5 MSTRG.125092.1_3 - 0.6 10.4 6.4 3.2 8.1 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 MSTRG.125092.1_3 - 9.9 6.1 11.3 0.28 11.1 3.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger DDE_3 PF13358.4 MSTRG.139350.1_1 - 3.9e-10 39.5 0.2 5.3e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Mcl1_mid PF12341.6 MSTRG.139350.1_3 - 0.063 12.5 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Q_salvage PF10343.7 MSTRG.58312.1_1 - 1.1e-15 57.9 0.0 1.3e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family zf-B_box PF00643.22 MSTRG.107417.1_2 - 3.4e-11 43.0 6.8 3.4e-11 43.0 6.8 1.9 2 0 0 2 2 2 1 B-box zinc finger FemAB_like PF04339.10 MSTRG.107417.1_2 - 0.021 13.9 0.4 0.021 13.8 0.4 1.1 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition BLOC1S3 PF15753.3 MSTRG.107417.1_2 - 0.023 14.7 0.4 0.032 14.2 0.4 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Jnk-SapK_ap_N PF09744.7 MSTRG.107417.1_2 - 0.065 13.3 5.7 0.05 13.7 4.7 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Lep_receptor_Ig PF06328.9 MSTRG.135753.1_3 - 4.4e-14 52.2 0.1 1.5e-13 50.4 0.1 1.9 1 0 0 1 1 1 1 Ig-like C2-type domain fn3 PF00041.19 MSTRG.135753.1_3 - 2.3e-11 43.7 5.9 3.3e-06 27.2 0.2 4.0 4 0 0 4 4 4 2 Fibronectin type III domain SusE PF14292.4 MSTRG.135753.1_3 - 0.011 16.0 0.2 0.93 9.8 0.0 3.0 3 0 0 3 3 3 0 SusE outer membrane protein IL6Ra-bind PF09240.8 MSTRG.135753.1_3 - 0.064 13.6 0.3 0.8 10.0 0.0 2.6 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding Ig_2 PF13895.4 MSTRG.135753.1_3 - 0.087 13.0 0.3 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain RRM_5 PF13893.4 MSTRG.50302.1_3 - 2.2e-20 72.4 0.2 2.7e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 MSTRG.50302.1_3 - 0.0025 17.4 0.0 0.0062 16.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 MSTRG.50302.1_3 - 0.022 14.5 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif DDE_3 PF13358.4 MSTRG.142975.1_1 - 4.6e-12 45.8 0.0 5.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FerA PF08165.9 MSTRG.79006.1_3 - 4.6e-09 36.0 0.6 2.9e-08 33.4 0.3 2.0 2 0 0 2 2 2 1 FerA (NUC095) domain IPK PF03770.14 MSTRG.126350.1_3 - 1.3e-40 139.2 0.0 2.2e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pkinase PF00069.23 MSTRG.141475.1_1 - 7.5e-61 205.7 0.0 1.1e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.141475.1_1 - 1.7e-36 125.8 0.0 2.1e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 MSTRG.141475.1_1 - 7e-05 22.1 0.1 0.0007 18.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.4 MSTRG.141475.1_1 - 0.0014 18.2 0.1 1.4 8.4 0.0 2.8 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.12 MSTRG.141475.1_1 - 0.0021 17.3 0.0 0.0058 15.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 MSTRG.141475.1_1 - 0.037 13.8 0.0 0.07 12.9 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family DHR-2 PF06920.11 MSTRG.51711.1_2 - 4.1e-29 101.5 1.5 4.7e-29 101.3 1.5 1.0 1 0 0 1 1 1 1 Dock homology region 2 NODP PF07684.10 MSTRG.51711.1_2 - 0.063 13.3 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 NOTCH protein HTHP PF11534.6 MSTRG.51711.1_2 - 0.075 13.3 0.0 6 7.2 0.0 2.0 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) A2M_recep PF07677.12 MSTRG.11048.1_3 - 1.5e-19 70.4 0.5 2.9e-19 69.5 0.5 1.5 1 0 0 1 1 1 1 A-macroglobulin receptor NTR PF01759.19 MSTRG.11048.1_3 - 1.5e-13 50.3 0.0 2.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Myosin_tail_1 PF01576.17 MSTRG.72821.1_3 - 1.2e-05 23.2 17.8 1.4e-05 23.0 17.8 1.0 1 0 0 1 1 1 1 Myosin tail Syntaxin-6_N PF09177.9 MSTRG.72821.1_3 - 0.042 14.3 4.4 0.042 14.3 4.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal THP2 PF09432.8 MSTRG.72821.1_3 - 0.061 13.2 5.3 0.11 12.5 5.2 1.5 1 1 0 1 1 1 0 Tho complex subunit THP2 Lebercilin PF15619.4 MSTRG.72821.1_3 - 0.086 12.4 18.4 0.11 12.0 18.4 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Ribosomal_L29 PF00831.21 MSTRG.72821.1_3 - 0.14 12.0 11.8 0.23 11.3 3.8 2.3 2 0 0 2 2 2 0 Ribosomal L29 protein ERM PF00769.17 MSTRG.72821.1_3 - 0.39 10.4 21.6 0.52 10.0 21.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.6 MSTRG.72821.1_3 - 0.44 10.5 17.5 0.39 10.6 16.1 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.10 MSTRG.72821.1_3 - 0.49 10.3 8.1 4 7.3 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.3 MSTRG.72821.1_3 - 0.6 10.9 18.2 0.33 11.7 8.6 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Jnk-SapK_ap_N PF09744.7 MSTRG.72821.1_3 - 0.73 9.9 19.1 0.93 9.6 19.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Trp_leader2 PF08056.9 MSTRG.72821.1_3 - 1.1 9.2 6.2 2.1 8.3 0.3 2.8 3 0 0 3 3 3 0 Tryptophan operon leader peptide Caudo_TAP PF02413.15 MSTRG.72821.1_3 - 1.2 9.3 10.2 1.7 8.8 10.1 1.5 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK DUF4404 PF14357.4 MSTRG.72821.1_3 - 2 9.0 17.0 4.7 7.8 9.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Golgin_A5 PF09787.7 MSTRG.72821.1_3 - 2.2 7.5 17.5 3 7.1 17.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1151 PF06625.9 MSTRG.72821.1_3 - 2.2 8.1 17.4 0.23 11.3 9.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) Spc7 PF08317.9 MSTRG.72821.1_3 - 2.3 6.9 17.2 3.2 6.4 17.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.7 MSTRG.72821.1_3 - 3.8 6.4 13.8 4.8 6.0 13.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.4 MSTRG.72821.1_3 - 4.1 6.5 13.7 5 6.2 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.8 MSTRG.72821.1_3 - 4.4 7.4 11.7 6.2 6.9 11.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HR1 PF02185.14 MSTRG.72821.1_3 - 5.3 7.1 15.3 38 4.4 14.9 2.9 1 1 0 1 1 1 0 Hr1 repeat FUSC PF04632.10 MSTRG.72821.1_3 - 6.5 5.0 5.5 6.9 5.0 5.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4695 PF15766.3 MSTRG.72821.1_3 - 6.5 6.9 10.0 0.89 9.7 5.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4695) Exonuc_VII_L PF02601.13 MSTRG.72821.1_3 - 9.4 5.6 12.7 9.9 5.5 12.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1816 PF08846.8 MSTRG.102373.1_1 - 0.074 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) NYAP_C PF15452.4 MSTRG.142378.1_3 - 0.0059 16.3 5.2 0.0074 16.0 5.1 1.3 1 1 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Asp-B-Hydro_N PF05279.9 MSTRG.142378.1_3 - 0.64 9.9 10.2 0.7 9.8 10.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2477 PF10631.7 MSTRG.142378.1_3 - 1.1 9.8 6.3 1.6 9.3 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) fn3 PF00041.19 MSTRG.49664.1_2 - 4e-102 334.6 7.5 4.8e-16 58.8 0.1 8.3 8 0 0 8 8 8 8 Fibronectin type III domain I-set PF07679.14 MSTRG.49664.1_2 - 2.7e-35 120.2 1.6 2.2e-14 53.2 0.0 5.9 6 0 0 6 6 6 3 Immunoglobulin I-set domain Pur_ac_phosph_N PF16656.3 MSTRG.49664.1_2 - 1.5e-19 70.2 1.1 0.012 16.0 0.1 7.9 7 0 0 7 7 7 5 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.4 MSTRG.49664.1_2 - 1.6e-16 60.6 7.0 7e-09 36.0 0.0 5.3 6 0 0 6 6 6 2 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.49664.1_2 - 3.7e-08 33.5 0.1 0.00017 21.7 0.0 3.7 3 0 0 3 3 3 1 Immunoglobulin domain Y_Y_Y PF07495.11 MSTRG.49664.1_2 - 2.9e-05 23.8 0.1 8.5 6.3 0.0 5.8 7 0 0 7 7 7 1 Y_Y_Y domain ig PF00047.23 MSTRG.49664.1_2 - 5.9e-05 23.0 0.0 0.015 15.3 0.0 2.9 2 0 0 2 2 2 1 Immunoglobulin domain DUF11 PF01345.16 MSTRG.49664.1_2 - 0.0034 17.5 0.1 18 5.6 0.0 4.1 3 1 0 3 3 3 0 Domain of unknown function DUF11 Cadherin PF00028.15 MSTRG.49664.1_2 - 0.0054 17.0 0.0 6.6 7.1 0.0 4.5 5 0 0 5 5 5 1 Cadherin domain V-set PF07686.15 MSTRG.49664.1_2 - 0.0084 16.1 0.0 0.48 10.5 0.0 3.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain YcgR_2 PF12945.5 MSTRG.49664.1_2 - 0.0091 16.0 0.1 0.78 9.8 0.0 3.5 4 0 0 4 4 4 1 Flagellar protein YcgR C2-set_2 PF08205.10 MSTRG.49664.1_2 - 0.014 15.3 0.2 0.1 12.6 0.0 2.5 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain CRA_rpt PF07046.9 MSTRG.49664.1_2 - 1.6 8.9 12.0 3.6 7.7 12.0 1.5 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat TPD52 PF04201.13 MSTRG.46157.1_3 - 0.0028 17.1 0.3 0.0038 16.7 0.3 1.2 1 0 0 1 1 1 1 Tumour protein D52 family NTR PF01759.19 MSTRG.132734.1_2 - 0.14 11.9 0.0 0.85 9.3 0.0 1.9 2 0 0 2 2 2 0 UNC-6/NTR/C345C module rve PF00665.24 MSTRG.26834.1_2 - 0.025 14.7 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Propep_M14 PF02244.14 MSTRG.26834.1_2 - 0.039 14.2 0.0 0.048 13.9 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase activation peptide UMPH-1 PF05822.10 MSTRG.5367.1_1 - 1.7e-44 152.1 1.2 1.9e-44 151.9 1.2 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Lysyl_oxidase PF01186.15 MSTRG.143868.1_3 - 7.3e-39 133.4 3.5 8.1e-39 133.3 3.5 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.9 MSTRG.143868.1_3 - 0.011 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 CARDB Acyl-CoA_dh_N PF02771.14 MSTRG.40882.1_1 - 8.7e-06 26.2 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HTH_23 PF13384.4 MSTRG.61451.1_1 - 0.0071 16.0 0.2 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.4 MSTRG.61451.1_1 - 0.036 13.7 0.2 0.06 13.0 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.13 MSTRG.61451.1_1 - 0.063 13.2 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.81748.1_3 - 1.9e-22 79.1 1.7 1.9e-22 79.1 1.7 1.7 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.4 MSTRG.81748.1_3 - 2.5e-06 27.9 1.8 6.2e-06 26.6 1.8 1.7 1 1 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.4 MSTRG.81748.1_3 - 3.1e-05 23.5 0.5 0.0044 16.7 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain VacA2 PF03077.12 MSTRG.129298.1_2 - 0.24 11.1 0.6 0.37 10.5 0.6 1.2 1 0 0 1 1 1 0 Putative vacuolating cytotoxin DUF202 PF02656.13 MSTRG.53924.1_1 - 5 7.5 7.1 0.52 10.7 0.8 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF202) PHD PF00628.27 MSTRG.18006.1_3 - 1.4e-12 47.2 7.9 2.1e-12 46.6 7.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.4 MSTRG.18006.1_3 - 0.0018 18.4 2.1 0.0018 18.4 2.1 1.9 1 1 1 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.4 MSTRG.18006.1_3 - 0.02 14.3 1.7 0.02 14.3 1.7 2.0 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.4 MSTRG.18006.1_3 - 0.025 14.6 1.8 0.025 14.6 1.8 1.6 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-RING_2 PF13639.4 MSTRG.18006.1_3 - 0.031 14.4 7.5 0.045 13.9 7.5 1.3 1 0 0 1 1 1 0 Ring finger domain zf-PHD-like PF15446.4 MSTRG.18006.1_3 - 0.04 13.4 1.3 0.04 13.4 1.3 1.9 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.4 MSTRG.18006.1_3 - 0.045 13.6 3.7 0.045 13.6 3.7 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zf_RING PF16744.3 MSTRG.18006.1_3 - 0.048 13.6 9.6 2.5 8.1 9.6 2.2 1 1 0 1 1 1 0 KIAA1045 RING finger PolC_DP2 PF03833.11 MSTRG.18006.1_3 - 0.078 10.7 0.4 0.082 10.6 0.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-FPG_IleRS PF06827.12 MSTRG.18006.1_3 - 0.25 11.1 7.4 1.7 8.5 0.0 3.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS NADH-G_4Fe-4S_3 PF10588.7 MSTRG.18006.1_3 - 0.31 10.5 5.1 1.2 8.6 0.2 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-RING_9 PF13901.4 MSTRG.18006.1_3 - 0.8 9.5 6.0 3.5 7.4 6.1 1.8 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_1 PF00130.20 MSTRG.18006.1_3 - 1.1 9.1 9.1 0.2 11.4 3.1 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4611 PF15387.4 MSTRG.101792.1_1 - 6.6e-17 61.4 0.5 8.2e-17 61.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Vma12 PF11712.6 MSTRG.74317.1_1 - 0.27 11.1 2.1 0.3 11.0 2.1 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3377 PF11857.6 MSTRG.127135.1_3 - 2.4 8.0 6.9 5.5 6.9 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) fn3 PF00041.19 MSTRG.81358.1_2 - 9.7e-09 35.3 0.0 1.2e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin type III domain Ets PF00178.20 MSTRG.39972.1_1 - 3.2e-30 104.3 1.5 5.1e-30 103.6 1.5 1.3 1 0 0 1 1 1 1 Ets-domain Ion_trans PF00520.29 MSTRG.24457.1_2 - 4e-30 104.7 8.7 4e-30 104.7 8.7 2.8 4 0 0 4 4 4 1 Ion transport protein GPHH PF16905.3 MSTRG.24457.1_2 - 6.6e-05 22.5 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.25 MSTRG.24457.1_2 - 0.09 12.5 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif FtsX PF02687.19 MSTRG.123505.1_2 - 3.1 7.7 11.5 3.4 7.5 2.7 2.0 1 1 1 2 2 2 0 FtsX-like permease family Pkinase_Tyr PF07714.15 MSTRG.95769.1_2 - 5.6e-31 107.6 0.0 6e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 MSTRG.95769.1_2 - 3.5e-08 33.0 0.0 3.5e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Herpes_HEPA PF03324.12 MSTRG.95769.1_2 - 0.094 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein DUF4717 PF15838.3 MSTRG.10733.1_3 - 0.091 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) Bap31 PF05529.10 MSTRG.112182.1_3 - 0.58 9.6 5.3 0.78 9.2 5.3 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like ATP_synth_reg PF14960.4 MSTRG.143645.1_2 - 9.2e-23 79.4 0.5 1.3e-22 78.9 0.5 1.2 1 0 0 1 1 1 1 ATP synthase regulation HTH_Tnp_Tc3_2 PF01498.16 MSTRG.96549.1_2 - 2.3e-12 46.9 0.5 2.3e-12 46.9 0.5 1.5 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.4 MSTRG.96549.1_2 - 0.027 14.9 0.0 0.046 14.2 0.0 1.5 1 1 0 1 1 1 0 Homeodomain-like domain eIF-6 PF01912.16 MSTRG.100718.3_1 - 2e-15 56.6 0.1 2.4e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 eIF-6 family DUF2624 PF11116.6 MSTRG.100718.3_3 - 0.12 13.2 0.0 0.14 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) RSS_P20 PF11757.6 MSTRG.100718.3_3 - 0.13 12.4 0.2 0.2 11.8 0.2 1.3 1 1 0 1 1 1 0 Suppressor of RNA silencing P21-like Glyco_transf_7C PF02709.12 MSTRG.134929.1_2 - 0.097 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase SelP_N PF04592.12 MSTRG.138589.1_3 - 0.6 9.3 19.3 0.61 9.3 19.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lamp PF01299.15 MSTRG.138589.1_3 - 2.4 7.5 15.3 2.6 7.4 15.3 1.0 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Zip PF02535.20 MSTRG.138589.1_3 - 5.6 6.0 11.3 5.6 5.9 11.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter IL8 PF00048.18 MSTRG.2344.1_3 - 7.7e-16 57.9 2.2 1.1e-15 57.3 2.2 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like RVT_1 PF00078.25 MSTRG.100418.1_2 - 1e-11 44.6 0.0 1.2e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Y_phosphatase PF00102.25 MSTRG.55742.1_3 - 1.7e-54 184.8 3.5 1.9e-54 184.6 3.5 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPLA PF04387.12 MSTRG.121099.1_1 - 0.018 14.7 1.2 0.097 12.3 0.2 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase-like protein, PTPLA DUF1816 PF08846.8 MSTRG.121099.1_3 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) DUF4727 PF15856.3 MSTRG.141013.1_2 - 0.081 12.4 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) ITI_HC_C PF06668.10 MSTRG.127962.1_3 - 0.00082 18.9 0.1 0.001 18.6 0.1 1.1 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus zf-met PF12874.5 MSTRG.127419.1_1 - 0.76 10.1 4.3 2.4 8.5 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Glyco_transf_7C PF02709.12 MSTRG.31528.1_3 - 0.0001 21.7 0.2 0.00011 21.6 0.2 1.1 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Acetyltransf_1 PF00583.23 MSTRG.105896.1_2 - 6.4e-08 32.7 0.0 9.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.5 MSTRG.105896.1_2 - 5.9e-06 26.1 0.0 9.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 MSTRG.105896.1_2 - 0.00024 21.3 0.0 0.00042 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain E1-E2_ATPase PF00122.18 MSTRG.136454.1_1 - 9.4e-58 195.0 1.6 1.4e-57 194.5 1.6 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.4 MSTRG.136454.1_1 - 6.5e-23 80.5 0.0 1.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.24 MSTRG.136454.1_1 - 8.6e-18 63.6 0.0 1.5e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.24 MSTRG.136454.1_1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.9 MSTRG.136454.1_1 - 0.32 10.9 7.0 14 5.6 4.2 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III EGF_2 PF07974.11 MSTRG.140898.1_2 - 4.7e-12 45.9 74.3 0.00046 20.3 8.3 5.1 5 0 0 5 5 5 4 EGF-like domain EGF PF00008.25 MSTRG.140898.1_2 - 1e-05 25.6 57.8 0.0044 17.2 7.7 5.5 4 1 0 4 4 4 4 EGF-like domain hEGF PF12661.5 MSTRG.140898.1_2 - 0.0099 16.4 49.5 0.16 12.6 8.2 6.4 5 2 0 5 5 5 4 Human growth factor-like EGF Caveolin PF01146.15 MSTRG.69762.1_2 - 0.038 13.8 1.0 0.046 13.5 1.0 1.3 1 0 0 1 1 1 0 Caveolin Pkinase PF00069.23 MSTRG.10021.1_3 - 1.3e-21 77.0 0.3 1.4e-21 76.9 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.10021.1_3 - 9.7e-09 34.7 0.1 9.8e-09 34.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 MSTRG.10021.1_3 - 0.0064 15.7 0.0 0.0064 15.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 MSTRG.10021.1_3 - 0.011 14.9 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.20 MSTRG.10021.1_3 - 0.02 14.4 0.2 0.022 14.2 0.2 1.0 1 0 0 1 1 1 0 RIO1 family 5_nucleotid PF05761.12 MSTRG.10021.1_3 - 0.054 12.3 0.0 0.054 12.2 0.0 1.0 1 0 0 1 1 1 0 5' nucleotidase family APH PF01636.21 MSTRG.10021.1_3 - 0.073 12.8 0.0 0.097 12.4 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Prok-RING_1 PF14446.4 MSTRG.55154.2_3 - 0.0013 18.5 0.3 0.005 16.6 0.3 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD PF00628.27 MSTRG.55154.2_3 - 0.016 14.9 2.0 0.016 14.9 2.0 2.4 2 0 0 2 2 2 0 PHD-finger PHD_2 PF13831.4 MSTRG.55154.2_3 - 2.1 7.8 10.0 0.17 11.3 1.9 2.5 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.20 MSTRG.55154.2_3 - 2.4 8.0 11.1 16 5.4 11.1 2.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF776 PF05604.9 MSTRG.56685.1_2 - 0.095 12.9 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF776) DUF3694 PF12473.6 MSTRG.98452.1_3 - 0.011 16.3 0.0 0.024 15.2 0.0 1.6 2 0 0 2 2 2 0 Kinesin protein Peptidase_M14 PF00246.22 MSTRG.15444.1_2 - 4.5e-45 154.6 1.7 7.5e-45 153.8 0.0 2.1 2 1 0 2 2 2 1 Zinc carboxypeptidase F5_F8_type_C PF00754.23 MSTRG.15444.1_2 - 2.4e-26 92.2 1.2 3.2e-26 91.8 0.1 1.8 2 0 0 2 2 2 1 F5/8 type C domain DUF1510 PF07423.9 MSTRG.15444.1_2 - 0.00084 18.7 3.4 0.00084 18.7 3.4 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1510) Pneumo_att_G PF05539.9 MSTRG.15444.1_2 - 0.11 11.9 13.8 0.19 11.2 13.8 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G BACON PF13004.5 MSTRG.37532.1_2 - 0.016 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative binding domain, N-terminal ATP-gua_Ptrans PF00217.17 MSTRG.76648.2_3 - 6.2e-83 278.0 0.0 8.2e-83 277.6 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.13 MSTRG.76648.2_3 - 1.3e-33 115.1 0.0 2.3e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF4211 PF13926.4 MSTRG.24188.1_3 - 0.049 13.6 0.0 0.081 12.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) fn3 PF00041.19 MSTRG.36998.1_1 - 1.1e-06 28.8 0.0 1.2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.3 MSTRG.36998.1_1 - 0.038 14.4 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain EMP70 PF02990.14 MSTRG.7331.1_1 - 1.3e-05 24.0 0.1 1.5e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Helicase_C PF00271.29 MSTRG.695.1_2 - 0.0093 16.2 0.9 0.032 14.5 0.2 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SPOB_ab PF14682.4 MSTRG.695.1_2 - 0.016 15.2 3.5 0.017 15.1 0.9 2.0 1 1 1 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal START PF01852.17 MSTRG.23426.1_1 - 1.6e-08 34.1 0.6 1.8e-08 33.9 0.6 1.1 1 0 0 1 1 1 1 START domain DUF1534 PF07551.9 MSTRG.23426.1_3 - 0.18 11.4 3.3 0.81 9.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1534) DUF1669 PF07894.10 MSTRG.84808.1_1 - 1.4e-17 64.1 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) DUF3976 PF13121.4 MSTRG.49827.1_3 - 0.15 12.4 1.1 0.56 10.5 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3976) FA_desaturase PF00487.22 MSTRG.90349.1_3 - 1.1e-10 41.7 6.3 1.1e-10 41.7 6.3 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.8 MSTRG.90349.1_3 - 2.3e-10 39.6 0.3 4.7e-10 38.6 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) I-set PF07679.14 MSTRG.72571.1_1 - 1.8e-17 63.0 0.3 5e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.72571.1_1 - 3.9e-12 46.5 0.1 7.7e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 MSTRG.72571.1_1 - 0.00018 21.5 0.1 0.0016 18.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.72571.1_1 - 0.00029 21.0 0.0 0.053 13.7 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 MSTRG.72571.1_1 - 0.014 15.4 0.0 5.4 7.1 0.0 3.2 2 1 1 3 3 3 0 Immunoglobulin V-set domain Thioredoxin PF00085.18 MSTRG.54270.2_2 - 3.4e-34 116.8 0.0 8.1e-29 99.5 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.4 MSTRG.54270.2_2 - 0.00083 19.2 0.0 0.0043 16.9 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.11 MSTRG.54270.2_2 - 0.0018 17.6 0.1 0.0029 16.9 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 MSTRG.54270.2_2 - 0.0027 18.0 0.3 0.013 15.8 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.4 MSTRG.54270.2_2 - 0.047 13.9 0.1 0.17 12.1 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.4 MSTRG.54270.2_2 - 0.05 13.7 1.1 0.15 12.2 0.1 2.2 3 0 0 3 3 3 0 Thioredoxin-like Glyco_hydro_15 PF00723.19 MSTRG.260.1_1 - 1.4e-06 27.3 0.0 1.4e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Integrin_alpha PF00357.18 MSTRG.25848.1_3 - 0.0022 17.7 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.3 MSTRG.25848.1_3 - 0.017 14.6 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Catalase PF00199.17 MSTRG.106321.1_1 - 7.9e-12 44.8 0.0 9.4e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Collagen PF01391.16 MSTRG.60986.1_2 - 1.3e-19 69.5 81.8 2.2e-09 36.8 27.1 3.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Actin PF00022.17 MSTRG.92160.1_2 - 6.1e-68 229.2 0.0 6.6e-67 225.7 0.0 1.9 1 1 0 1 1 1 1 Actin SepSecS PF05889.11 MSTRG.97287.1_3 - 3.3e-92 309.1 0.0 3.7e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GshA PF08886.9 MSTRG.54231.1_1 - 0.038 12.4 0.0 0.052 12.0 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase DTW PF03942.13 MSTRG.3410.1_1 - 4.4e-05 23.1 0.1 5.9e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 DTW domain TB PF00683.15 MSTRG.121045.1_1 - 0.0089 15.6 0.6 0.015 14.8 0.6 1.3 1 0 0 1 1 1 1 TB domain DDE_3 PF13358.4 MSTRG.120237.1_1 - 8.1e-13 48.2 0.1 1.3e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.4 MSTRG.120237.1_1 - 7.2e-05 22.4 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.120237.1_1 - 0.00098 18.7 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.120237.1_3 - 4.4e-17 61.9 0.3 7.2e-17 61.3 0.3 1.3 1 0 0 1 1 1 1 Transposase Cornifin PF02389.13 MSTRG.94644.1_1 - 0.00091 19.3 0.1 0.0012 18.9 0.1 1.2 1 0 0 1 1 1 1 Cornifin (SPRR) family Clathrin_lg_ch PF01086.15 MSTRG.102316.1_1 - 3.8e-19 69.5 0.0 4.4e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Clathrin light chain HTH_38 PF13936.4 MSTRG.66490.1_2 - 0.00035 20.2 0.1 0.00059 19.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.66490.1_2 - 0.017 14.8 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Rib_recp_KP_reg PF05104.10 MSTRG.60196.1_1 - 1.9e-06 28.9 31.3 1.9e-06 28.9 31.3 5.6 2 2 5 7 7 7 1 Ribosome receptor lysine/proline rich region TMF_DNA_bd PF12329.6 MSTRG.60196.1_1 - 0.006 16.4 6.5 0.006 16.4 6.5 14.6 10 3 3 15 15 15 3 TATA element modulatory factor 1 DNA binding ParD_antitoxin PF03693.12 MSTRG.60196.1_1 - 0.62 10.4 7.2 10 6.5 0.5 3.5 3 0 0 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Lip_prot_lig_C PF10437.7 MSTRG.60196.1_1 - 4.1 7.3 5.6 51 3.8 0.1 4.1 3 1 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus zf-B_box PF00643.22 MSTRG.73512.1_2 - 0.00035 20.5 6.8 0.00068 19.6 6.8 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-BED PF02892.13 MSTRG.73512.1_2 - 0.15 12.0 3.1 0.27 11.2 3.1 1.3 1 0 0 1 1 1 0 BED zinc finger CaiF_GrlA PF07180.9 MSTRG.29663.1_3 - 0.023 14.5 0.4 0.026 14.3 0.4 1.1 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator NMD3 PF04981.11 MSTRG.33080.1_1 - 0.081 12.2 2.6 0.096 12.0 2.6 1.0 1 0 0 1 1 1 0 NMD3 family IP_trans PF02121.16 MSTRG.32974.1_1 - 5.7e-08 32.5 1.1 5.7e-08 32.5 1.1 2.2 3 0 0 3 3 3 1 Phosphatidylinositol transfer protein CDC50 PF03381.13 MSTRG.135807.1_1 - 4.4e-94 314.9 0.1 5.8e-94 314.5 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF2157 PF09925.7 MSTRG.135807.1_1 - 0.11 12.2 0.4 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3955 PF13127.4 MSTRG.135807.1_1 - 3.9 7.2 9.4 8.9 6.1 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3955) VWA PF00092.26 MSTRG.78089.1_3 - 9.4e-10 38.9 1.1 1.4e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.4 MSTRG.78089.1_3 - 1.3e-06 28.9 0.4 2.1e-06 28.2 0.4 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain PA28_beta PF02252.16 MSTRG.12948.1_3 - 2.9e-21 75.5 0.1 4.7e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit TSP_1 PF00090.17 MSTRG.20435.1_3 - 0.0042 17.1 8.2 0.01 15.9 8.2 1.7 1 1 0 1 1 1 1 Thrombospondin type 1 domain p25-alpha PF05517.10 MSTRG.144190.1_1 - 1.3e-30 106.5 0.5 1.4e-30 106.4 0.5 1.0 1 0 0 1 1 1 1 p25-alpha DDE_3 PF13358.4 MSTRG.74540.1_1 - 1.6e-05 24.6 0.0 1.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease AMP-binding PF00501.26 MSTRG.92790.1_3 - 4.2e-58 196.8 0.0 5.6e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GSG-1 PF07803.9 MSTRG.92790.1_3 - 0.084 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 GSG1-like protein Bromodomain PF00439.23 MSTRG.91985.2_3 - 1.3e-05 25.0 1.1 2.9e-05 23.9 0.2 1.9 2 0 0 2 2 2 1 Bromodomain Hep_core_N PF08290.9 MSTRG.41538.1_1 - 0.038 13.8 0.4 0.038 13.8 0.4 2.5 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger AreA_N PF07573.9 MSTRG.41538.1_1 - 0.29 11.7 1.4 1.9 9.0 0.0 2.5 2 1 1 3 3 3 0 Nitrogen regulatory protein AreA N terminus Rap_GAP PF02145.13 MSTRG.41538.1_3 - 1.3e-20 73.6 0.0 1.5e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Rap/ran-GAP Ecotin PF03974.11 MSTRG.41538.1_3 - 0.15 12.0 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Ecotin DUF3493 PF11998.6 MSTRG.41265.1_3 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) DUF4087 PF13316.4 MSTRG.9356.1_2 - 0.037 14.4 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4087) DUF2973 PF11189.6 MSTRG.4069.1_1 - 0.089 12.8 1.2 0.16 11.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) DUF865 PF05906.9 MSTRG.100560.1_1 - 7.4 6.3 9.4 16 5.2 2.9 2.6 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) Zip PF02535.20 MSTRG.45389.1_2 - 8.3e-29 100.7 4.4 6.6e-28 97.7 4.4 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter TraI_2 PF07514.9 MSTRG.45389.1_2 - 0.13 11.1 0.0 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 Putative helicase CtIP_N PF10482.7 MSTRG.64899.1_1 - 3.2e-06 27.1 0.2 3.6e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain TSKS PF15358.4 MSTRG.64899.1_1 - 0.024 12.9 1.3 0.028 12.7 1.3 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate SlyX PF04102.10 MSTRG.64899.1_1 - 0.027 15.0 1.2 0.048 14.1 1.2 1.4 1 0 0 1 1 1 0 SlyX IncA PF04156.12 MSTRG.64899.1_1 - 0.079 12.6 0.7 0.086 12.5 0.7 1.1 1 0 0 1 1 1 0 IncA protein Pkinase_C PF00433.22 MSTRG.66601.1_3 - 2e-10 41.0 4.4 3.6e-10 40.2 4.4 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain ANTH PF07651.14 MSTRG.76711.1_1 - 1.5e-16 60.1 0.0 1.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 ANTH domain Furin-like PF00757.18 MSTRG.60567.1_1 - 2.9e-31 108.2 35.7 3.9e-31 107.8 35.7 1.1 1 0 0 1 1 1 1 Furin-like cysteine rich region GF_recep_IV PF14843.4 MSTRG.60567.1_1 - 3.1e-06 26.9 44.4 0.00023 20.8 27.1 4.1 1 1 1 2 2 2 2 Growth factor receptor domain IV Recep_L_domain PF01030.22 MSTRG.60567.1_1 - 0.0085 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Receptor L domain SOCS_box PF07525.14 MSTRG.63838.1_2 - 0.0041 17.3 2.4 0.0079 16.4 2.4 1.5 1 0 0 1 1 1 1 SOCS box HTH_Tnp_Tc3_2 PF01498.16 MSTRG.8671.1_1 - 0.006 16.7 0.3 0.0087 16.1 0.3 1.2 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.8671.1_3 - 0.0005 20.1 0.1 0.00074 19.6 0.1 1.2 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.4 MSTRG.8671.1_3 - 0.013 16.0 0.1 0.014 15.8 0.1 1.1 1 0 0 1 1 1 0 Homeodomain-like domain CC2D2AN-C2 PF15625.4 MSTRG.93686.1_1 - 0.037 13.7 0.1 0.056 13.1 0.1 1.2 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain TauD PF02668.14 MSTRG.105.1_2 - 3.6e-06 26.8 0.0 4.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.8 MSTRG.105.1_2 - 0.023 13.7 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 CsiD PPK2 PF03976.12 MSTRG.38170.1_2 - 0.027 13.8 0.0 0.031 13.6 0.0 1.0 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) HBM PF16591.3 MSTRG.38170.1_2 - 0.049 12.9 0.1 0.058 12.7 0.1 1.0 1 0 0 1 1 1 0 Helical bimodular sensor domain UvrD_C_2 PF13538.4 MSTRG.81272.1_1 - 0.11 12.2 1.5 10 5.9 0.2 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Antimicrobial14 PF08109.9 MSTRG.81272.1_2 - 0.16 11.9 2.0 2.2 8.3 0.3 2.1 2 0 0 2 2 2 0 Lactocin 705 family UvrD_C_2 PF13538.4 MSTRG.81272.1_3 - 0.07 12.8 1.5 7.7 6.3 0.1 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain TSCPD PF12637.5 MSTRG.7119.1_3 - 0.065 13.3 0.2 0.13 12.4 0.2 1.4 1 1 0 1 1 1 0 TSCPD domain TraK PF06586.9 MSTRG.48809.1_2 - 0.015 14.8 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 TraK protein DDE_3 PF13358.4 MSTRG.66088.1_1 - 2.7e-10 40.1 0.0 2.7e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.16 MSTRG.29810.1_2 - 0.028 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Transposase (partial DDE domain) HTH_38 PF13936.4 MSTRG.47461.1_1 - 0.013 15.1 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2816 PF10992.6 MSTRG.125800.1_2 - 0.17 11.7 3.0 3.2 7.6 3.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2816) DUF1541 PF07563.9 MSTRG.125800.1_3 - 0.33 10.7 1.2 16 5.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1541) NHL PF01436.19 MSTRG.144242.1_3 - 6.1e-30 101.6 11.8 2.2e-07 30.4 0.2 4.6 4 0 0 4 4 4 4 NHL repeat Filamin PF00630.17 MSTRG.144242.1_3 - 1.6e-16 60.8 0.2 6.3e-16 58.9 0.0 2.0 2 1 0 2 2 2 1 Filamin/ABP280 repeat DUF5128 PF17170.2 MSTRG.144242.1_3 - 4.3e-11 42.4 4.3 1.3e-06 27.7 0.2 4.0 2 1 2 4 4 4 3 6-bladed beta-propeller SGL PF08450.10 MSTRG.144242.1_3 - 7.4e-07 28.9 0.4 0.0061 16.0 0.2 3.8 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region DUF4934 PF16288.3 MSTRG.144242.1_3 - 0.00016 21.4 1.8 0.21 11.4 0.0 3.6 2 1 0 3 3 3 2 Domain of unknown function (DUF4934) YtkA PF13115.4 MSTRG.144242.1_3 - 0.061 13.8 0.2 0.23 11.9 0.2 2.0 1 0 0 1 1 1 0 YtkA-like VCBS PF13517.4 MSTRG.144242.1_3 - 0.082 13.4 3.4 6.3 7.3 0.2 4.1 1 1 3 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Neurexophilin PF06312.10 MSTRG.144242.1_3 - 0.11 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Neurexophilin Filament PF00038.19 MSTRG.91642.2_2 - 8.6e-106 353.9 32.8 9.6e-106 353.7 32.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein ADIP PF11559.6 MSTRG.91642.2_2 - 0.00027 20.9 23.8 0.0074 16.2 0.2 4.1 1 1 2 4 4 4 2 Afadin- and alpha -actinin-Binding GAS PF13851.4 MSTRG.91642.2_2 - 0.0018 17.6 27.9 0.083 12.1 0.6 3.3 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.7 MSTRG.91642.2_2 - 0.0071 16.2 33.2 0.34 10.8 15.7 4.6 1 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.10 MSTRG.91642.2_2 - 0.0079 16.1 32.7 0.071 13.0 2.0 4.4 1 1 3 4 4 4 2 TPR/MLP1/MLP2-like protein DUF1664 PF07889.10 MSTRG.91642.2_2 - 0.017 14.9 23.0 0.25 11.2 3.4 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) FlxA PF14282.4 MSTRG.91642.2_2 - 0.019 14.8 1.9 0.019 14.8 1.9 5.0 2 2 2 4 4 4 0 FlxA-like protein Atg14 PF10186.7 MSTRG.91642.2_2 - 0.1 11.5 21.5 1.4 7.7 8.5 2.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.10 MSTRG.91642.2_2 - 0.11 12.4 15.2 2.6 8.0 7.8 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2461 PF09365.8 MSTRG.91642.2_2 - 0.12 12.2 4.0 0.21 11.4 0.2 2.8 2 1 1 3 3 3 0 Conserved hypothetical protein (DUF2461) DUF4686 PF15742.3 MSTRG.91642.2_2 - 0.43 9.5 29.4 0.79 8.6 10.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Sipho_Gp157 PF05565.9 MSTRG.91642.2_2 - 0.68 9.8 19.5 2.6 7.9 5.2 3.9 1 1 1 3 3 3 0 Siphovirus Gp157 Gp-FAR-1 PF05823.10 MSTRG.91642.2_2 - 0.85 9.8 8.1 0.09 13.0 1.6 2.5 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ATG16 PF08614.9 MSTRG.91642.2_2 - 0.92 9.5 30.9 0.54 10.3 6.4 3.3 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.4 MSTRG.91642.2_2 - 1.1 8.5 18.4 0.47 9.6 8.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Lectin_N PF03954.12 MSTRG.91642.2_2 - 1.5 8.4 19.6 0.24 11.0 2.3 4.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain IncA PF04156.12 MSTRG.91642.2_2 - 1.6 8.3 33.3 4.1 7.0 0.9 3.3 1 1 2 3 3 3 0 IncA protein FAM76 PF16046.3 MSTRG.91642.2_2 - 1.8 7.7 18.6 5.9 6.0 6.6 2.4 1 1 1 2 2 2 0 FAM76 protein Prefoldin_2 PF01920.18 MSTRG.91642.2_2 - 3.4 7.5 29.2 0.35 10.7 1.3 5.2 4 1 1 5 5 5 0 Prefoldin subunit Golgin_A5 PF09787.7 MSTRG.91642.2_2 - 3.5 6.9 33.1 1.2 8.4 16.2 3.0 1 1 1 3 3 3 0 Golgin subfamily A member 5 DUF972 PF06156.11 MSTRG.91642.2_2 - 9.6 6.8 28.8 0.92 10.0 2.3 4.9 2 1 1 3 3 2 0 Protein of unknown function (DUF972) 7tm_3 PF00003.20 MSTRG.60515.1_2 - 9.3e-34 117.1 12.2 1e-33 116.9 12.2 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR SP24 PF16504.3 MSTRG.60515.1_2 - 0.012 15.5 1.8 0.023 14.6 1.8 1.5 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus RhodobacterPufX PF11511.6 MSTRG.60515.1_2 - 0.31 10.5 0.1 0.31 10.5 0.1 1.9 3 0 0 3 3 3 0 Intrinsic membrane protein PufX zf-H2C2_2 PF13465.4 MSTRG.74668.1_1 - 1.2e-15 57.0 5.9 2.2e-11 43.5 0.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.74668.1_1 - 1.9e-13 49.9 4.3 5.1e-08 32.8 1.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.74668.1_1 - 5.8e-11 42.1 3.9 0.00017 22.0 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.5 MSTRG.74668.1_1 - 3.7e-07 30.2 2.1 0.00092 19.4 0.6 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 MSTRG.74668.1_1 - 6.3e-07 29.1 1.1 0.022 14.6 0.3 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.74668.1_1 - 4.7e-06 26.6 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.9 MSTRG.74668.1_1 - 5.2e-06 26.0 0.2 0.012 15.3 0.0 2.2 1 1 1 2 2 2 2 GAGA factor zf-H2C2_5 PF13909.4 MSTRG.74668.1_1 - 0.00021 20.9 2.4 0.00039 20.0 0.8 2.0 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-Di19 PF05605.10 MSTRG.74668.1_1 - 0.0012 19.0 0.3 0.0017 18.5 0.3 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.4 MSTRG.74668.1_1 - 0.0024 17.6 1.0 0.11 12.2 0.1 2.5 2 1 0 2 2 2 1 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.8 MSTRG.74668.1_1 - 0.0031 17.5 0.8 0.0049 16.8 0.8 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-Dof PF02701.13 MSTRG.74668.1_1 - 0.012 15.6 0.7 0.085 12.9 0.1 2.1 1 1 1 2 2 2 0 Dof domain, zinc finger DUF4764 PF15961.3 MSTRG.74668.1_1 - 0.034 12.7 0.4 2.3 6.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf-AN1 PF01428.14 MSTRG.74668.1_1 - 0.053 13.6 1.1 6.1 7.0 0.1 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger FYVE PF01363.19 MSTRG.74668.1_1 - 0.063 13.3 1.3 0.82 9.7 1.2 2.0 1 1 0 1 1 1 0 FYVE zinc finger Cript PF10235.7 MSTRG.74668.1_1 - 0.1 13.1 0.2 0.2 12.1 0.2 1.6 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT FYDLN_acid PF09538.8 MSTRG.74668.1_1 - 0.1 13.1 0.3 2.5 8.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-BED PF02892.13 MSTRG.74668.1_1 - 0.13 12.2 1.0 12 5.9 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger Zf_RING PF16744.3 MSTRG.74668.1_1 - 0.17 11.9 0.9 12 6.0 0.1 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C2H2_11 PF16622.3 MSTRG.74668.1_1 - 0.25 11.0 10.3 0.63 9.7 0.5 2.6 3 0 0 3 3 3 0 zinc-finger C2H2-type TBPIP PF07106.11 MSTRG.51408.1_2 - 2e-28 99.1 6.4 4.3e-19 68.8 3.1 2.0 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.12 MSTRG.51408.1_2 - 0.0014 18.4 2.5 0.0016 18.2 2.5 1.1 1 0 0 1 1 1 1 IncA protein TFIIE_beta PF02186.13 MSTRG.51408.1_2 - 0.0014 18.7 0.1 0.72 10.1 0.0 2.4 2 0 0 2 2 2 1 TFIIE beta subunit core domain HBM PF16591.3 MSTRG.51408.1_2 - 0.0039 16.5 0.1 0.0071 15.7 0.1 1.4 1 1 0 1 1 1 1 Helical bimodular sensor domain SKA1 PF07160.10 MSTRG.51408.1_2 - 0.01 15.5 2.0 0.015 15.1 2.0 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF16 PF01519.14 MSTRG.51408.1_2 - 0.014 15.7 2.0 0.026 14.9 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.10 MSTRG.51408.1_2 - 0.016 15.1 0.4 0.022 14.6 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.4 MSTRG.51408.1_2 - 0.016 15.5 1.6 0.035 14.4 1.6 1.6 1 1 0 1 1 1 0 Snapin/Pallidin Mnd1 PF03962.13 MSTRG.51408.1_2 - 0.016 14.9 3.9 0.026 14.2 3.6 1.4 1 1 1 2 2 2 0 Mnd1 family MCPsignal PF00015.19 MSTRG.51408.1_2 - 0.016 14.8 0.7 0.021 14.5 0.7 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.9 MSTRG.51408.1_2 - 0.018 13.8 2.3 0.022 13.5 2.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Asp1 PF16993.3 MSTRG.51408.1_2 - 0.019 14.1 0.1 0.021 14.0 0.1 1.1 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 Seryl_tRNA_N PF02403.20 MSTRG.51408.1_2 - 0.024 14.7 2.2 0.94 9.6 0.7 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.10 MSTRG.51408.1_2 - 0.026 13.8 0.2 0.032 13.5 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein KELK PF15796.3 MSTRG.51408.1_2 - 0.031 14.6 0.7 0.079 13.3 0.5 1.7 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NPV_P10 PF05531.10 MSTRG.51408.1_2 - 0.043 14.1 0.7 0.1 13.0 0.7 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PRKG1_interact PF15898.3 MSTRG.51408.1_2 - 0.046 14.5 1.6 0.2 12.5 0.4 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain XhlA PF10779.7 MSTRG.51408.1_2 - 0.058 13.5 0.8 0.24 11.5 0.2 2.1 1 1 1 2 2 2 0 Haemolysin XhlA DUF4988 PF16378.3 MSTRG.51408.1_2 - 0.072 12.5 0.2 0.098 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function TPR_MLP1_2 PF07926.10 MSTRG.51408.1_2 - 0.076 12.9 3.3 0.15 12.0 3.3 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SPT16 PF08644.9 MSTRG.51408.1_2 - 0.076 13.1 0.7 0.099 12.7 0.7 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) LPP PF04728.11 MSTRG.51408.1_2 - 0.09 13.0 0.7 6.6 7.1 0.7 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ADIP PF11559.6 MSTRG.51408.1_2 - 0.097 12.6 3.3 0.13 12.2 3.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CCDC-167 PF15188.4 MSTRG.51408.1_2 - 0.15 12.3 1.7 1.6 9.0 0.1 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 HTH_Tnp_Tc3_2 PF01498.16 MSTRG.39869.1_3 - 3.9e-07 30.1 2.0 1.1e-06 28.7 2.0 1.8 1 1 0 1 1 1 1 Transposase Rho_Binding PF08912.9 MSTRG.97484.1_3 - 0.00025 21.7 1.6 0.00025 21.7 1.6 3.1 2 1 0 2 2 2 1 Rho Binding CENP-F_leu_zip PF10473.7 MSTRG.97484.1_3 - 0.0057 16.5 20.8 0.027 14.3 8.9 2.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.4 MSTRG.97484.1_3 - 0.059 12.6 17.5 0.49 9.6 17.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cortex-I_coil PF09304.8 MSTRG.97484.1_3 - 0.16 12.0 16.2 0.37 10.9 7.8 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF4201 PF13870.4 MSTRG.97484.1_3 - 0.17 11.4 15.9 0.12 11.9 4.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HIP1_clath_bdg PF16515.3 MSTRG.97484.1_3 - 0.24 11.9 13.2 0.12 12.8 6.5 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF501 PF04417.10 MSTRG.97484.1_3 - 0.31 10.7 6.3 1 9.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF501) ERM PF00769.17 MSTRG.97484.1_3 - 0.34 10.6 18.4 1.9 8.1 18.4 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family APG6 PF04111.10 MSTRG.97484.1_3 - 1.2 8.3 17.7 2.6 7.2 17.7 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Cnn_1N PF07989.9 MSTRG.97484.1_3 - 2 8.5 17.5 0.24 11.4 9.3 2.7 1 1 1 2 2 1 0 Centrosomin N-terminal motif 1 MCM_N PF14551.4 MSTRG.97484.1_3 - 2.9 8.4 7.4 6.8 7.2 0.2 2.5 1 1 1 2 2 2 0 MCM N-terminal domain TMF_DNA_bd PF12329.6 MSTRG.97484.1_3 - 3.3 7.6 19.1 0.17 11.8 4.0 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.9 MSTRG.97484.1_3 - 4.4 6.0 19.1 8.1 5.1 19.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.124999.1_1 - 3.3e-18 65.6 1.9 7.2e-18 64.5 1.9 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.4 MSTRG.124999.1_1 - 1.7e-05 24.5 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_12 PF08461.8 MSTRG.124999.1_1 - 0.014 15.2 0.3 0.036 13.9 0.3 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_23 PF13384.4 MSTRG.124999.1_1 - 0.11 12.2 1.5 3.4 7.4 0.0 3.5 4 0 0 4 4 4 0 Homeodomain-like domain ApoO PF09769.7 MSTRG.137240.1_3 - 0.084 12.7 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein O ArgoN PF16486.3 MSTRG.11666.1_1 - 1e-11 45.5 0.1 1.2e-11 45.2 0.1 1.0 1 0 0 1 1 1 1 N-terminal domain of argonaute HalX PF08663.8 MSTRG.80106.1_3 - 0.093 12.9 0.7 0.11 12.6 0.7 1.1 1 0 0 1 1 1 0 HalX domain RabGAP-TBC PF00566.16 MSTRG.62776.1_3 - 2.5e-09 37.0 0.0 3.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_N PF01602.18 MSTRG.45414.1_2 - 3.1e-19 68.8 0.2 3.3e-19 68.7 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF2240 PF09999.7 MSTRG.45414.1_2 - 0.11 12.0 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) EF-hand_7 PF13499.4 MSTRG.29694.1_2 - 2.9e-11 43.5 6.8 7.9e-10 38.9 2.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.30 MSTRG.29694.1_2 - 5.3e-10 38.0 6.1 0.00089 18.5 0.0 4.0 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.4 MSTRG.29694.1_2 - 2.2e-09 36.3 8.8 0.00078 19.1 0.6 4.6 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.4 MSTRG.29694.1_2 - 7.3e-05 22.3 8.2 0.24 11.1 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.4 MSTRG.29694.1_2 - 0.0058 16.0 7.7 0.56 9.7 0.1 3.6 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.7 MSTRG.29694.1_2 - 0.11 12.7 0.1 0.7 10.1 0.1 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 MSTRG.29694.1_2 - 0.14 12.0 3.1 1.3 8.9 0.1 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand HTH_38 PF13936.4 MSTRG.23611.1_1 - 0.00035 20.2 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Ribosomal_S13_N PF08069.10 MSTRG.23611.1_1 - 0.055 13.4 0.8 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain HTH_23 PF13384.4 MSTRG.23611.1_1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain PH PF00169.27 MSTRG.123210.1_2 - 9e-05 22.8 0.1 0.00011 22.5 0.1 1.2 1 0 0 1 1 1 1 PH domain Plant_all_beta PF10532.7 MSTRG.123210.1_2 - 0.045 13.9 0.1 0.051 13.7 0.1 1.2 1 0 0 1 1 1 0 Plant specific N-all beta domain RVT_1 PF00078.25 MSTRG.86506.1_2 - 5.1e-07 29.3 0.0 6.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaxin-18_N PF10496.7 MSTRG.14181.1_2 - 8e-22 77.1 0.6 1.1e-21 76.8 0.2 1.4 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF326 PF03860.14 MSTRG.35999.1_3 - 0.12 12.3 0.7 0.22 11.4 0.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) DDE_3 PF13358.4 MSTRG.126069.1_1 - 0.00016 21.4 0.1 0.00026 20.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.16 MSTRG.126069.1_2 - 0.0001 22.3 0.1 0.00021 21.3 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.16 MSTRG.126069.1_3 - 2.5e-05 24.3 0.9 6.3e-05 23.0 0.9 1.7 1 0 0 1 1 1 1 Transposase DUF16 PF01519.14 MSTRG.10194.1_2 - 0.00015 22.1 0.2 0.00021 21.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 Reo_sigmaC PF04582.10 MSTRG.10194.1_2 - 0.031 13.5 0.3 0.046 13.0 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein WHEP-TRS PF00458.18 MSTRG.10194.1_2 - 0.06 13.4 0.1 0.096 12.7 0.1 1.3 1 0 0 1 1 1 0 WHEP-TRS domain HGD-D PF06050.11 MSTRG.10194.1_2 - 0.095 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component NPV_P10 PF05531.10 MSTRG.10194.1_2 - 0.15 12.4 0.1 0.26 11.7 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.6 MSTRG.10194.1_2 - 0.37 10.9 5.8 0.12 12.4 2.6 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.3 MSTRG.10194.1_2 - 0.76 9.8 5.0 0.65 10.0 1.3 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation UPF0547 PF10571.7 MSTRG.87465.1_1 - 0.13 12.3 0.3 0.28 11.2 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Syja_N PF02383.16 MSTRG.87465.1_3 - 3.6e-40 138.0 0.0 5.4e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain PAX PF00292.16 MSTRG.116009.1_2 - 0.024 14.4 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.116009.1_3 - 6.9e-07 29.3 0.3 1.8e-06 28.0 0.3 1.6 1 0 0 1 1 1 1 Transposase FRG1 PF06229.10 MSTRG.9480.1_1 - 8.8e-30 103.7 8.1 1e-29 103.5 8.1 1.1 1 0 0 1 1 1 1 FRG1-like domain ANATO PF01821.16 MSTRG.58433.1_1 - 0.044 14.5 0.5 0.9 10.3 0.1 2.1 2 0 0 2 2 2 0 Anaphylotoxin-like domain I-set PF07679.14 MSTRG.84784.1_3 - 2.6e-09 36.9 0.0 3.1e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.84784.1_3 - 0.00022 21.7 0.0 0.00028 21.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.84784.1_3 - 0.015 15.5 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.23 MSTRG.84784.1_3 - 0.031 14.3 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain RVT_1 PF00078.25 MSTRG.88002.1_2 - 0.013 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ELM2 PF01448.22 MSTRG.51195.1_1 - 0.00029 21.4 0.0 0.00055 20.5 0.0 1.5 1 0 0 1 1 1 1 ELM2 domain zf-H2C2_2 PF13465.4 MSTRG.74502.1_3 - 3.4e-17 61.9 16.7 3.1e-08 33.6 0.1 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.74502.1_3 - 2.7e-12 46.3 19.4 1.3e-06 28.4 1.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.74502.1_3 - 7.8e-11 41.7 17.5 2.2e-05 24.8 0.8 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.5 MSTRG.74502.1_3 - 1.2e-06 28.6 10.8 0.0078 16.4 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 MSTRG.74502.1_3 - 2.8e-05 24.2 4.3 0.012 15.7 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.10 MSTRG.74502.1_3 - 3.9e-05 23.7 7.4 0.011 15.9 3.1 2.1 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.4 MSTRG.74502.1_3 - 8.9e-05 22.2 18.5 0.02 14.7 0.2 3.8 3 1 0 3 3 3 2 C2H2-type zinc finger zf-LYAR PF08790.9 MSTRG.74502.1_3 - 0.00016 21.4 1.8 0.089 12.6 0.1 2.5 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.8 MSTRG.74502.1_3 - 0.0004 20.3 12.3 0.041 13.9 7.4 2.3 2 0 0 2 2 2 2 Zinc ribbon domain DUF3268 PF11672.6 MSTRG.74502.1_3 - 0.0042 17.3 4.7 0.0053 17.0 1.7 1.9 2 0 0 2 2 2 1 zinc-finger-containing domain zf-ISL3 PF14690.4 MSTRG.74502.1_3 - 0.015 15.8 13.4 0.31 11.6 2.3 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2HC_2 PF13913.4 MSTRG.74502.1_3 - 0.045 13.5 0.1 0.045 13.5 0.1 3.7 3 1 0 3 3 3 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.12 MSTRG.74502.1_3 - 0.081 12.6 7.2 0.25 11.1 0.2 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif HypA PF01155.17 MSTRG.74502.1_3 - 0.083 12.8 6.8 1.6 8.7 3.7 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L37ae PF01780.17 MSTRG.74502.1_3 - 0.13 12.2 10.2 2.3 8.2 5.7 2.9 1 1 1 2 2 2 0 Ribosomal L37ae protein family ADK_lid PF05191.12 MSTRG.74502.1_3 - 0.15 11.9 8.7 4.3 7.3 5.5 2.6 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.5 MSTRG.74502.1_3 - 0.23 11.7 9.1 1.8 8.8 0.1 2.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SprT-like PF10263.7 MSTRG.74502.1_3 - 0.63 9.7 10.0 7 6.3 10.1 2.0 1 1 0 1 1 1 0 SprT-like family zf-CHCC PF10276.7 MSTRG.74502.1_3 - 0.74 9.8 9.9 8.1 6.5 0.7 3.1 3 0 0 3 3 3 0 Zinc-finger domain XPA_N PF01286.16 MSTRG.74502.1_3 - 0.77 9.7 9.5 1 9.4 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal Zn_Tnp_IS1595 PF12760.5 MSTRG.74502.1_3 - 0.77 9.6 16.5 3.7e+02 1.1 16.5 2.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain CpXC PF14353.4 MSTRG.74502.1_3 - 0.82 9.6 8.7 3.5 7.6 0.1 3.0 1 1 2 3 3 3 0 CpXC protein OrfB_Zn_ribbon PF07282.9 MSTRG.74502.1_3 - 0.99 9.2 13.3 1.6 8.6 0.3 2.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.10 MSTRG.74502.1_3 - 1.4 9.2 17.8 9.9 6.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase TerY_C PF15616.4 MSTRG.74502.1_3 - 1.6 8.7 7.7 1.5 8.8 4.0 1.9 1 1 1 2 2 2 0 TerY-C metal binding domain Cys_rich_CPCC PF14206.4 MSTRG.74502.1_3 - 1.7 8.4 9.2 17 5.2 0.1 2.5 2 1 0 2 2 2 0 Cysteine-rich CPCC FYVE PF01363.19 MSTRG.74502.1_3 - 1.9 8.5 13.7 13 5.9 13.7 2.2 1 1 0 1 1 1 0 FYVE zinc finger YhfH PF14149.4 MSTRG.74502.1_3 - 2 8.4 11.5 4.9 7.1 0.1 3.1 3 0 0 3 3 3 0 YhfH-like protein DUF2256 PF10013.7 MSTRG.74502.1_3 - 2.3 8.3 12.0 2.9 8.0 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) FYDLN_acid PF09538.8 MSTRG.74502.1_3 - 2.4 8.7 9.9 6.9 7.3 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) FdhE PF04216.10 MSTRG.74502.1_3 - 2.6 7.7 10.9 0.048 13.4 2.7 1.8 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation zf-ribbon_3 PF13248.4 MSTRG.74502.1_3 - 2.6 7.4 16.6 0.79 9.1 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain HNH PF01844.21 MSTRG.74502.1_3 - 4.5 7.4 12.2 9.4 6.4 0.1 3.1 3 0 0 3 3 3 0 HNH endonuclease DUF983 PF06170.10 MSTRG.74502.1_3 - 8.5 6.7 8.0 27 5.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Zn_ribbon_recom PF13408.4 MSTRG.74502.1_3 - 9.7 6.7 15.0 5.5 7.5 0.2 2.9 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DDE_3 PF13358.4 MSTRG.77822.1_2 - 9.6e-05 22.0 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Y_phosphatase PF00102.25 MSTRG.133260.1_2 - 0.012 15.1 0.0 0.012 15.1 0.0 1.0 1 0 0 1 1 1 0 Protein-tyrosine phosphatase IL6Ra-bind PF09240.8 MSTRG.101951.1_3 - 9.5e-05 22.6 0.5 0.00014 22.1 0.5 1.2 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding IL4Ra_N PF09238.8 MSTRG.101951.1_3 - 0.00062 19.9 0.6 0.00099 19.3 0.6 1.3 1 0 0 1 1 1 1 Interleukin-4 receptor alpha chain, N-terminal DUF1816 PF08846.8 MSTRG.64698.1_1 - 0.037 13.9 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) ig PF00047.23 MSTRG.57359.1_1 - 0.00032 20.7 0.1 0.0012 18.9 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 MSTRG.57359.1_1 - 0.0031 17.5 0.2 0.0088 16.1 0.2 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 MSTRG.57359.1_1 - 0.047 14.2 0.1 0.14 12.7 0.1 1.8 1 1 0 1 1 1 0 Immunoglobulin domain Izumo-Ig PF16706.3 MSTRG.57359.1_1 - 0.075 13.0 0.1 0.85 9.6 0.0 2.2 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Herpes_US9 PF06072.9 MSTRG.66388.1_1 - 0.3 10.9 0.8 0.45 10.3 0.8 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 PAP2 PF01569.19 MSTRG.15423.1_3 - 6.7e-27 93.8 3.0 1.7e-26 92.5 3.0 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.4 MSTRG.15423.1_3 - 0.0014 18.9 3.1 0.0014 18.9 3.1 2.3 2 0 0 2 2 2 1 PAP2 superfamily C-terminal CobS_N PF12556.6 MSTRG.68331.1_2 - 0.062 12.9 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal Troponin PF00992.18 MSTRG.118041.1_2 - 6.9e-36 123.4 5.5 9.8e-36 122.9 5.5 1.2 1 0 0 1 1 1 1 Troponin NTR2 PF15458.4 MSTRG.118041.1_2 - 0.0026 17.3 0.3 0.0026 17.3 0.3 1.5 2 0 0 2 2 2 1 Nineteen complex-related protein 2 Carn_acyltransf PF00755.18 MSTRG.118041.1_2 - 0.0053 15.3 0.1 0.0064 15.0 0.1 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2951 PF11166.6 MSTRG.118041.1_2 - 0.01 15.9 3.1 0.01 15.9 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) XhlA PF10779.7 MSTRG.118041.1_2 - 0.011 15.8 1.1 0.011 15.8 1.1 2.0 2 0 0 2 2 2 0 Haemolysin XhlA Spc7 PF08317.9 MSTRG.118041.1_2 - 0.024 13.4 4.1 0.041 12.6 4.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.12 MSTRG.118041.1_2 - 0.26 10.9 2.4 0.57 9.8 2.4 1.8 1 1 0 1 1 1 0 IncA protein DUF4404 PF14357.4 MSTRG.118041.1_2 - 0.28 11.8 6.7 3.9 8.1 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF724 PF05266.12 MSTRG.118041.1_2 - 0.42 10.3 7.7 1.1 8.9 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.10 MSTRG.118041.1_2 - 0.46 10.3 5.8 0.28 11.0 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SNF PF00209.16 MSTRG.76845.1_1 - 3.7e-37 128.1 4.3 3.9e-37 128.0 4.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family TPR_1 PF00515.26 MSTRG.6218.1_2 - 2.5e-09 36.4 5.3 0.00017 21.1 0.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.15 MSTRG.6218.1_2 - 1.5e-06 27.8 5.6 0.045 13.8 1.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.4 MSTRG.6218.1_2 - 0.00022 20.7 6.8 0.02 14.4 0.2 3.2 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.4 MSTRG.6218.1_2 - 0.00024 21.2 0.4 0.093 12.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.4 MSTRG.6218.1_2 - 0.0038 17.2 2.8 2.1 8.6 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.16 MSTRG.6218.1_2 - 0.032 14.2 4.4 1.1 9.3 0.4 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain EzrA PF06160.10 MSTRG.6218.1_2 - 0.056 11.5 0.1 0.081 11.0 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA MIP PF00230.18 MSTRG.109645.1_2 - 8.3e-18 64.8 0.5 1.1e-17 64.4 0.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.112868.1_1 - 4.9e-16 58.6 0.1 9.4e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 Transposase ARS2 PF04959.11 MSTRG.101680.1_2 - 6.7e-89 297.3 0.9 1.3e-88 296.3 0.9 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Tim54 PF11711.6 MSTRG.101680.1_2 - 0.041 12.5 4.5 0.065 11.9 4.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Cwf_Cwc_15 PF04889.10 MSTRG.101680.1_2 - 0.15 11.6 25.4 0.27 10.8 25.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myosin_head PF00063.19 MSTRG.99434.1_1 - 5.9e-31 107.3 0.4 6.6e-31 107.1 0.4 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Bromodomain PF00439.23 MSTRG.68623.1_3 - 2.3e-16 59.5 0.0 3.6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain SRP-alpha_N PF04086.11 MSTRG.68623.1_3 - 1.7 8.4 11.3 2.2 8.0 11.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Myosin_head PF00063.19 MSTRG.100960.1_3 - 6.1e-67 226.2 3.2 6.7e-67 226.1 3.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Arteri_Gl PF00951.16 MSTRG.100960.1_3 - 0.038 13.7 0.5 0.23 11.1 0.0 2.3 2 1 1 3 3 3 0 Arterivirus GL envelope glycoprotein DUF1816 PF08846.8 MSTRG.137418.1_3 - 0.069 13.0 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) MCM_OB PF17207.1 MSTRG.90857.1_3 - 4.5e-11 42.6 1.2 4.9e-11 42.4 1.2 1.0 1 0 0 1 1 1 1 MCM OB domain I-set PF07679.14 MSTRG.73778.1_1 - 3.4e-13 49.3 0.1 3.7e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.73778.1_1 - 6.9e-09 36.1 0.0 9.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.73778.1_1 - 8e-09 35.6 0.0 8.7e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 MSTRG.73778.1_1 - 1.7e-08 34.4 0.1 2e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 MSTRG.73778.1_1 - 1e-07 31.9 0.3 0.002 18.1 0.1 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.3 MSTRG.73778.1_1 - 0.00015 21.9 0.1 0.0003 21.0 0.1 1.5 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.3 MSTRG.73778.1_1 - 0.0011 19.1 0.1 0.0053 17.0 0.1 1.8 1 1 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.3 MSTRG.73778.1_1 - 0.0075 16.2 0.1 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 Izumo-like Immunoglobulin domain Cep57_MT_bd PF06657.11 MSTRG.134471.1_3 - 0.15 12.4 2.4 0.24 11.7 2.4 1.2 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 HTH_23 PF13384.4 MSTRG.123294.1_1 - 0.0029 17.2 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Ant_C PF05586.9 MSTRG.98603.1_2 - 6.1e-48 161.2 0.3 1e-47 160.6 0.3 1.3 1 0 0 1 1 1 1 Anthrax receptor C-terminus region DUF3328 PF11807.6 MSTRG.98603.1_2 - 0.13 11.9 2.4 2.6 7.6 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) Myosin_head PF00063.19 MSTRG.60107.1_3 - 1.4e-55 188.7 4.2 1.5e-55 188.6 4.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) PC4 PF02229.14 MSTRG.60107.1_3 - 0.07 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) 7tm_1 PF00001.19 MSTRG.18339.1_3 - 9.9e-06 24.8 0.2 1.1e-05 24.7 0.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Plexin_cytopl PF08337.10 MSTRG.47630.1_3 - 6.8e-92 308.8 4.3 7.5e-92 308.6 4.3 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain ARL2_Bind_BART PF11527.6 MSTRG.47630.1_3 - 0.038 14.0 2.0 0.062 13.3 0.6 2.0 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART RhoGEF PF00621.18 MSTRG.61298.1_2 - 1.4e-07 31.8 0.1 2e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 RhoGEF domain Cytochrome_CBB3 PF13442.4 MSTRG.119870.1_1 - 0.038 14.2 1.4 1.7 8.9 0.4 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Pkinase PF00069.23 MSTRG.119870.1_2 - 1.9e-06 27.3 0.0 2.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 MSTRG.119870.1_2 - 0.011 14.9 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase tRNA_deacylase PF04414.10 MSTRG.78892.1_1 - 0.042 13.2 0.2 2.4 7.5 0.0 2.0 1 1 1 2 2 2 0 D-aminoacyl-tRNA deacylase SapA PF02199.13 MSTRG.78892.1_1 - 3.5 7.7 5.4 26 5.0 0.6 2.4 2 0 0 2 2 2 0 Saposin A-type domain Cadherin PF00028.15 MSTRG.132816.1_3 - 0.00025 21.3 0.5 0.00043 20.5 0.4 1.4 1 1 0 1 1 1 1 Cadherin domain T2SSB PF16537.3 MSTRG.132816.1_3 - 0.081 12.4 0.2 0.33 10.4 0.1 1.9 2 0 0 2 2 2 0 Type II secretion system protein B FEZ PF07763.11 MSTRG.11283.1_1 - 2.2e-17 63.5 0.3 2.9e-17 63.1 0.3 1.1 1 0 0 1 1 1 1 FEZ-like protein MamL-1 PF09596.8 MSTRG.141432.1_1 - 2.5e-15 56.3 5.7 3.4e-15 55.9 5.7 1.2 1 0 0 1 1 1 1 MamL-1 domain Sugarporin_N PF11471.6 MSTRG.113693.1_2 - 0.021 14.7 0.1 5 7.1 0.1 2.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension MNHE PF01899.14 MSTRG.143613.1_2 - 0.12 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit RVT_1 PF00078.25 MSTRG.121897.1_2 - 0.00046 19.6 0.0 0.00048 19.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 MSTRG.121897.1_3 - 3.4e-05 23.3 0.0 3.6e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VWC PF00093.16 MSTRG.7519.1_2 - 0.069 13.3 12.2 0.15 12.2 9.5 2.1 2 0 0 2 2 2 0 von Willebrand factor type C domain SCAMP PF04144.11 MSTRG.69183.1_2 - 2.8e-44 151.4 21.8 3.7e-44 151.0 21.8 1.1 1 0 0 1 1 1 1 SCAMP family Transglut_C PF00927.20 MSTRG.136491.1_1 - 5e-40 135.8 0.0 6.1e-22 77.6 0.0 2.2 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain ASH PF15780.3 MSTRG.136491.1_1 - 0.016 15.2 0.1 0.041 14.0 0.1 1.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin HTH_Tnp_Tc3_2 PF01498.16 MSTRG.136491.1_3 - 1.9e-07 31.1 0.7 3.5e-07 30.3 0.7 1.5 1 0 0 1 1 1 1 Transposase Totivirus_coat PF05518.9 MSTRG.67992.1_3 - 6.7 4.5 8.2 7.1 4.4 8.2 1.0 1 0 0 1 1 1 0 Totivirus coat protein HTH_Tnp_Tc3_2 PF01498.16 MSTRG.2028.1_3 - 2.8e-06 27.4 0.0 3.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Transposase Eapp_C PF10238.7 MSTRG.23130.1_3 - 5.4e-50 169.2 1.6 6.5e-50 169.0 1.6 1.0 1 0 0 1 1 1 1 E2F-associated phosphoprotein IBR PF01485.19 MSTRG.23130.1_3 - 0.0082 16.2 2.3 0.86 9.7 1.5 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain C1_4 PF07975.10 MSTRG.23130.1_3 - 0.012 15.7 2.4 0.025 14.7 0.3 2.3 3 0 0 3 3 3 0 TFIIH C1-like domain UPF0547 PF10571.7 MSTRG.23130.1_3 - 10 6.2 8.8 15 5.6 1.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 IL6Ra-bind PF09240.8 MSTRG.18023.1_2 - 1.5e-09 38.1 0.1 1.8e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding RVT_1 PF00078.25 MSTRG.125458.1_2 - 0.029 13.7 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 MSTRG.125458.1_3 - 3.7e-08 33.0 0.0 4.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3927 PF13064.4 MSTRG.129824.1_2 - 1.7 8.7 4.9 7.2 6.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3927) RVT_1 PF00078.25 MSTRG.89300.1_1 - 1.2e-08 34.6 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 MSTRG.89300.1_2 - 0.00016 21.2 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Inhibitor_I67 PF11405.6 MSTRG.89300.1_2 - 0.1 12.7 0.1 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 Bromelain inhibitor VI AAA_5 PF07728.12 MSTRG.23782.1_2 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Glyco_transf_7C PF02709.12 MSTRG.63742.1_1 - 1.5e-29 101.3 0.5 2e-29 100.9 0.5 1.1 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.4 MSTRG.63742.1_1 - 9.1e-11 41.4 0.7 1.3e-10 40.9 0.7 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 ZZ PF00569.15 MSTRG.88409.1_2 - 0.045 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type GBP PF02263.17 MSTRG.51149.1_2 - 4.3e-24 85.0 0.2 4.6e-24 84.9 0.2 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Gag_p19 PF02228.14 MSTRG.108094.1_1 - 0.054 13.8 6.2 6.2 7.2 0.5 3.2 1 1 2 3 3 3 0 Major core protein p19 Drf_FH1 PF06346.10 MSTRG.108094.1_1 - 0.42 10.1 25.6 0.091 12.3 12.3 2.0 1 1 0 1 1 1 0 Formin Homology Region 1 Lectin_leg-like PF03388.11 MSTRG.108094.1_3 - 0.59 9.3 5.9 1.6 7.9 1.8 2.1 1 1 1 2 2 2 0 Legume-like lectin family DUF1079 PF06435.9 MSTRG.108094.1_3 - 0.96 9.6 11.5 48 4.2 0.0 6.0 4 1 3 7 7 7 0 Repeat of unknown function (DUF1079) bZIP_1 PF00170.19 MSTRG.17254.1_3 - 1.7e-08 34.3 5.9 3e-08 33.5 5.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 MSTRG.17254.1_3 - 8.6e-05 22.4 3.9 8.6e-05 22.4 3.9 1.7 1 1 0 1 1 1 1 Basic region leucine zipper FlaC_arch PF05377.9 MSTRG.17254.1_3 - 0.0024 18.1 0.6 0.005 17.1 0.6 1.5 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) TSC22 PF01166.16 MSTRG.17254.1_3 - 0.078 13.2 4.2 2.7 8.2 1.7 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family Kinetocho_Slk19 PF12709.5 MSTRG.17254.1_3 - 0.086 13.2 2.0 0.17 12.2 2.0 1.5 1 0 0 1 1 1 0 Central kinetochore-associated ZapB PF06005.10 MSTRG.17254.1_3 - 0.14 12.5 3.2 0.26 11.6 3.2 1.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_Maf PF03131.15 MSTRG.17254.1_3 - 0.18 12.2 1.6 0.29 11.6 1.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.13 MSTRG.17254.1_3 - 0.42 10.3 2.8 1 9.1 2.8 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF1736 PF08409.9 MSTRG.33277.1_3 - 0.0051 16.7 0.1 0.0064 16.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) M157 PF11624.6 MSTRG.26241.1_2 - 0.17 11.0 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 MHC class I-like protein M157 RVT_1 PF00078.25 MSTRG.112175.1_2 - 0.0034 16.8 0.0 0.0039 16.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.5 MSTRG.26868.1_2 - 0.016 15.7 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) GlcNAc_2-epim PF07221.9 MSTRG.115674.1_1 - 7.9e-14 51.5 0.1 1.4e-13 50.7 0.0 1.3 1 1 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) zf-H2C2_5 PF13909.4 MSTRG.68251.1_1 - 0.046 13.3 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Med8 PF10232.7 MSTRG.119186.1_3 - 2.1e-83 279.3 0.0 2.8e-83 278.9 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 ATP_synt_H PF05493.11 MSTRG.93976.1_2 - 1.9e-22 79.4 6.2 2.7e-22 78.9 6.2 1.2 1 0 0 1 1 1 1 ATP synthase subunit H Porin_3 PF01459.20 MSTRG.59576.1_2 - 2.6e-18 66.3 0.1 2.7e-18 66.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin SusE PF14292.4 MSTRG.59576.1_2 - 0.015 15.5 0.1 0.016 15.4 0.1 1.1 1 0 0 1 1 1 0 SusE outer membrane protein DAGK_acc PF00609.17 MSTRG.124509.1_2 - 5.4e-18 65.7 0.3 6.8e-18 65.4 0.3 1.1 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain Kazal_1 PF00050.19 MSTRG.94757.1_1 - 1.2e-12 47.5 1.6 1.2e-12 47.5 1.6 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 MSTRG.94757.1_1 - 6e-08 32.6 2.0 6e-08 32.6 2.0 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain LSM PF01423.20 MSTRG.15430.1_1 - 1.8e-13 49.8 0.1 3.1e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 LSM domain Glycos_transf_2 PF00535.24 MSTRG.31522.1_3 - 4.5e-15 55.7 0.0 5e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.7 MSTRG.31522.1_3 - 0.0096 15.3 0.0 0.01 15.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 UPF0254 PF06787.9 MSTRG.579.3_1 - 0.047 13.3 0.5 0.061 13.0 0.4 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0254) EF-hand_1 PF00036.30 MSTRG.29912.2_1 - 4.3e-24 82.1 12.6 0.0013 18.0 0.8 6.5 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.4 MSTRG.29912.2_1 - 5.7e-22 77.8 16.9 1.7e-07 31.5 1.2 4.2 3 1 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 MSTRG.29912.2_1 - 3.3e-19 67.0 10.8 0.018 14.8 0.0 6.4 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.4 MSTRG.29912.2_1 - 2e-14 52.2 20.5 0.0022 17.3 0.6 6.3 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.4 MSTRG.29912.2_1 - 4.4e-12 45.4 12.5 0.087 12.5 0.1 5.7 6 0 0 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.7 MSTRG.29912.2_1 - 6.1e-07 29.6 11.5 0.0096 16.1 0.6 3.3 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region DUF3192 PF11399.6 MSTRG.29912.2_1 - 0.054 13.3 0.5 0.35 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) Gla PF00594.18 MSTRG.42882.1_1 - 1.8e-13 50.3 6.2 7.5e-13 48.3 5.1 2.1 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF3717 PF12512.6 MSTRG.10136.1_1 - 0.0088 15.8 3.2 4 7.3 0.1 4.8 6 0 0 6 6 6 2 Protein of unknown function (DUF3717) C1_4 PF07975.10 MSTRG.97705.1_2 - 0.017 15.2 2.3 0.027 14.6 2.3 1.3 1 0 0 1 1 1 0 TFIIH C1-like domain Vault PF01505.16 MSTRG.91783.1_2 - 2.1e-44 149.4 6.0 5.8e-17 61.6 0.1 4.3 4 0 0 4 4 4 3 Major Vault Protein repeat DUF3601 PF12208.6 MSTRG.91783.1_2 - 0.01 15.8 0.0 1.3 9.1 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3601) Cohesin_load PF10345.7 MSTRG.137812.1_3 - 1.4e-11 43.5 0.1 1.4e-11 43.4 0.1 1.0 1 0 0 1 1 1 1 Cohesin loading factor Ribosomal_L4 PF00573.20 MSTRG.5945.1_3 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Oxidored_q2 PF00420.22 MSTRG.5945.1_3 - 0.16 11.5 2.7 1.7 8.2 0.0 2.8 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MARVEL PF01284.21 MSTRG.5945.1_3 - 0.22 11.4 6.7 0.14 12.0 3.5 1.9 1 1 1 2 2 2 0 Membrane-associating domain DUF3535 PF12054.6 MSTRG.30526.1_2 - 0.022 13.9 4.0 0.025 13.7 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) P22_portal PF16510.3 MSTRG.30526.1_2 - 0.53 8.7 8.5 0.6 8.5 8.5 1.0 1 0 0 1 1 1 0 Phage P22-like portal protein Rrn6 PF10214.7 MSTRG.30526.1_2 - 0.79 7.9 14.0 0.84 7.8 14.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MAS20 PF02064.13 MSTRG.30526.1_2 - 0.95 9.4 9.3 1.2 9.1 9.3 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor DUF2681 PF10883.6 MSTRG.30526.1_2 - 1.8 8.9 15.3 2.5 8.4 15.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) GREB1 PF15782.3 MSTRG.30526.1_2 - 2.4 5.0 7.3 2.7 4.8 7.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.15 MSTRG.30526.1_2 - 4 5.9 7.5 4.3 5.8 7.5 1.0 1 0 0 1 1 1 0 Presenilin XK-related PF09815.7 MSTRG.75908.1_1 - 3.6e-14 52.6 5.5 4e-14 52.4 5.5 1.0 1 0 0 1 1 1 1 XK-related protein Herpes_LMP1 PF05297.9 MSTRG.75908.1_1 - 0.88 8.6 3.9 0.97 8.4 3.9 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3678 PF12435.6 MSTRG.11188.1_1 - 0.074 12.2 2.2 0.14 11.3 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) FliJ PF02050.14 MSTRG.113837.1_2 - 0.0038 17.3 2.9 0.0038 17.3 2.9 4.0 1 1 2 3 3 3 2 Flagellar FliJ protein TolA_bind_tri PF16331.3 MSTRG.113837.1_2 - 0.017 15.0 7.5 0.017 15.0 7.5 3.7 2 1 2 4 4 4 0 TolA binding protein trimerisation ADIP PF11559.6 MSTRG.113837.1_2 - 0.017 15.1 49.6 0.17 11.9 10.4 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.9 MSTRG.113837.1_2 - 0.12 12.5 2.2 1.6 8.9 0.5 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.10 MSTRG.113837.1_2 - 0.4 9.9 6.2 0.63 9.3 3.8 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.10 MSTRG.113837.1_2 - 9.6 6.1 17.4 1.3 8.9 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.19 MSTRG.51241.1_1 - 0.0098 16.2 2.2 0.0098 16.2 2.2 2.7 2 1 1 3 3 3 1 Spectrin repeat Peptidase_M13 PF01431.19 MSTRG.51241.1_1 - 0.012 15.1 0.3 0.2 11.1 0.0 2.0 1 1 1 2 2 2 0 Peptidase family M13 LPP PF04728.11 MSTRG.51241.1_1 - 0.023 14.9 0.5 1.2 9.4 0.1 2.6 1 1 1 2 2 2 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.7 MSTRG.51241.1_1 - 0.071 13.0 5.8 0.12 12.3 5.3 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rho_Binding PF08912.9 MSTRG.51241.1_1 - 0.8 10.4 5.1 0.43 11.3 0.4 2.6 3 0 0 3 3 3 0 Rho Binding IncA PF04156.12 MSTRG.51241.1_1 - 1.9 8.1 9.7 3.4 7.3 9.7 1.4 1 1 0 1 1 1 0 IncA protein ZapB PF06005.10 MSTRG.51241.1_1 - 3 8.2 12.2 37 4.7 7.3 2.9 2 1 0 2 2 2 0 Cell division protein ZapB JAKMIP_CC3 PF16034.3 MSTRG.51241.1_1 - 7.6 6.3 12.0 0.72 9.6 0.2 2.6 2 1 1 3 3 3 0 JAKMIP CC3 domain RasGEF PF00617.17 MSTRG.64762.1_2 - 4.4e-09 36.6 0.0 5.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain OAF PF14941.4 MSTRG.16749.1_3 - 8.7e-16 58.0 0.4 1.2e-15 57.5 0.4 1.2 1 0 0 1 1 1 1 Transcriptional regulator, Out at first HTH_29 PF13551.4 MSTRG.70494.1_2 - 0.0031 17.4 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix Plant_zn_clust PF10533.7 MSTRG.1883.1_1 - 0.0094 15.7 0.5 0.014 15.1 0.5 1.3 1 0 0 1 1 1 1 Plant zinc cluster domain CC2-LZ PF16516.3 MSTRG.127200.3_1 - 5.8e-32 110.0 16.0 5.8e-32 110.0 16.0 4.9 3 1 2 5 5 5 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HsbA PF12296.6 MSTRG.127200.3_1 - 4.8 7.5 8.7 9.7 6.5 0.3 3.1 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Spc7 PF08317.9 MSTRG.127200.3_1 - 7.4 5.2 51.3 0.075 11.8 15.5 4.0 3 1 1 4 4 4 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.17 MSTRG.127200.3_1 - 9.7 3.7 55.6 1.2 6.7 19.4 3.0 2 1 1 3 3 3 0 Myosin tail Occludin_ELL PF07303.11 MSTRG.139394.1_1 - 3.8e-32 110.9 11.0 3.8e-32 110.9 11.0 2.0 2 0 0 2 2 2 1 Occludin homology domain ELL PF10390.7 MSTRG.139394.1_1 - 4.2e-12 46.0 2.2 4.3e-12 46.0 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL DUF2353 PF09789.7 MSTRG.139394.1_1 - 0.0026 17.1 3.7 0.0026 17.1 3.7 1.9 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) Seryl_tRNA_N PF02403.20 MSTRG.139394.1_1 - 0.013 15.6 1.0 0.013 15.6 1.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain EzrA PF06160.10 MSTRG.139394.1_1 - 0.18 9.8 9.9 0.26 9.3 9.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4174 PF13778.4 MSTRG.110256.1_3 - 1.1e-30 106.4 0.0 1.4e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Sushi PF00084.18 MSTRG.110256.1_3 - 2.3e-09 37.6 5.4 4.2e-09 36.8 5.4 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) CLASP_N PF12348.6 MSTRG.1332.1_3 - 1.2 8.5 5.4 5.5 6.4 0.2 3.0 1 1 2 3 3 3 0 CLASP N terminal Kelch_6 PF13964.4 MSTRG.2940.1_1 - 7.9e-07 29.0 0.1 1.7e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.4 MSTRG.2940.1_1 - 9.6e-07 28.5 0.2 2.1e-06 27.5 0.2 1.6 1 1 0 1 1 1 1 Kelch motif Kelch_1 PF01344.23 MSTRG.2940.1_1 - 8.1e-06 25.2 0.1 1.5e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.13 MSTRG.2940.1_1 - 0.0027 17.5 4.1 0.022 14.6 2.8 2.7 2 1 0 2 2 2 1 Kelch motif Kelch_3 PF13415.4 MSTRG.2940.1_1 - 0.064 13.4 0.1 0.23 11.7 0.2 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_4 PF13418.4 MSTRG.2940.1_1 - 0.37 10.6 1.7 3 7.8 1.7 2.1 1 1 0 1 1 1 0 Galactose oxidase, central domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.87966.1_1 - 0.061 13.4 3.6 1.2 9.3 0.1 2.4 3 0 0 3 3 3 0 Transposase Nup153 PF08604.8 MSTRG.10697.1_3 - 9.9e-20 70.7 3.2 1.1e-19 70.5 3.2 1.0 1 0 0 1 1 1 1 Nucleoporin Nup153-like Rax2 PF12768.5 MSTRG.6795.1_1 - 0.0059 16.1 3.8 0.0065 16.0 3.8 1.0 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF912 PF06024.10 MSTRG.6795.1_1 - 0.013 15.6 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UL45 PF05473.10 MSTRG.6795.1_1 - 0.016 14.7 1.0 0.018 14.6 1.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like LRRC37AB_C PF14914.4 MSTRG.6795.1_1 - 0.018 14.8 0.7 0.021 14.6 0.7 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain TMEM154 PF15102.4 MSTRG.6795.1_1 - 0.049 13.4 7.9 0.058 13.2 7.9 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF3433 PF11915.6 MSTRG.6795.1_1 - 0.051 13.9 1.6 0.062 13.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) TMEM192 PF14802.4 MSTRG.6795.1_1 - 0.23 10.4 5.8 0.24 10.3 5.8 1.0 1 0 0 1 1 1 0 TMEM192 family PRIMA1 PF16101.3 MSTRG.6795.1_1 - 2.2 8.2 6.1 3.4 7.6 6.1 1.5 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 Rifin_STEVOR PF02009.14 MSTRG.6795.1_1 - 2.4 7.8 6.7 2.4 7.8 6.7 1.1 1 0 0 1 1 1 0 Rifin/stevor family CDK2AP PF09806.7 MSTRG.6795.1_2 - 0.43 10.5 2.4 0.46 10.4 2.4 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Halogen_Hydrol PF10112.7 MSTRG.6795.1_3 - 0.02 14.8 1.5 0.022 14.7 1.5 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4133 PF13571.4 MSTRG.6795.1_3 - 0.086 13.0 2.9 0.1 12.8 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) SelP_N PF04592.12 MSTRG.6795.1_3 - 0.65 9.2 27.4 0.7 9.1 27.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4231 PF14015.4 MSTRG.6795.1_3 - 1.3 9.4 7.6 1.6 9.1 7.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) EphA2_TM PF14575.4 MSTRG.6795.1_3 - 3.7 8.3 13.7 98 3.7 13.7 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MMPL PF03176.13 MSTRG.6795.1_3 - 9.3 4.9 7.6 9.3 4.9 7.6 1.1 1 0 0 1 1 1 0 MMPL family Calpain_inhib PF00748.17 MSTRG.93195.2_2 - 2.2e-31 108.9 22.6 6.3e-26 91.3 4.4 3.1 3 0 0 3 3 3 3 Calpain inhibitor Ribosom_S30AE_C PF16321.3 MSTRG.93195.2_2 - 0.0051 16.4 0.2 1.4 8.6 0.1 2.4 2 0 0 2 2 2 2 Sigma 54 modulation/S30EA ribosomal protein C terminus Med16 PF11635.6 MSTRG.93195.2_2 - 0.022 12.6 0.1 1.1 6.9 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 16 DUF4731 PF15875.3 MSTRG.2315.1_2 - 0.066 13.3 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) RVT_1 PF00078.25 MSTRG.99288.1_3 - 8.6e-06 25.3 0.0 9.7e-06 25.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zinc-ribbon_6 PF10005.7 MSTRG.99288.1_3 - 0.042 14.4 0.0 0.049 14.2 0.0 1.1 1 0 0 1 1 1 0 zinc-ribbon domain Adaptin_N PF01602.18 MSTRG.137927.1_2 - 2.5e-77 260.5 0.5 2.7e-77 260.4 0.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Kinetochor_Ybp2 PF08568.8 MSTRG.137927.1_2 - 0.0047 15.3 0.2 0.0095 14.3 0.1 1.5 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin Cnd1 PF12717.5 MSTRG.137927.1_2 - 0.0068 16.3 1.7 0.08 12.8 0.2 2.6 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Peptidase_M73 PF12389.6 MSTRG.137927.1_2 - 0.059 13.1 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Peptidase_C12 PF01088.19 MSTRG.26060.2_2 - 1.4e-26 93.4 0.0 1.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HTH_38 PF13936.4 MSTRG.109266.1_3 - 1.1e-05 24.9 0.1 1.8e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.109266.1_3 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.4 MSTRG.109266.1_3 - 0.00023 21.1 0.1 0.0004 20.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.4 MSTRG.109266.1_3 - 0.00044 20.1 0.1 0.0008 19.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4 PF04545.14 MSTRG.109266.1_3 - 0.0045 16.4 0.1 0.022 14.2 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_32 PF13565.4 MSTRG.109266.1_3 - 0.0098 16.4 1.8 0.042 14.3 1.6 1.9 1 1 1 2 2 2 1 Homeodomain-like domain PAX PF00292.16 MSTRG.109266.1_3 - 0.052 13.3 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 'Paired box' domain HTH_10 PF04967.10 MSTRG.109266.1_3 - 0.061 13.0 0.2 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 HTH DNA binding domain HTH_Tnp_ISL3 PF13542.4 MSTRG.109266.1_3 - 0.063 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 AAA_30 PF13604.4 MSTRG.109266.1_3 - 0.071 12.7 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain GerE PF00196.17 MSTRG.109266.1_3 - 0.084 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family MarR_2 PF12802.5 MSTRG.109266.1_3 - 0.088 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 MarR family Atrophin-1 PF03154.13 MSTRG.20532.1_1 - 9.7e-19 67.1 15.1 9.7e-19 67.1 15.1 2.6 1 1 1 2 2 2 1 Atrophin-1 family SelP_N PF04592.12 MSTRG.20532.1_1 - 0.51 9.6 21.7 0.59 9.4 21.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.20 MSTRG.20532.1_1 - 4.1 6.4 15.3 4.2 6.4 15.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Nrf1_DNA-bind PF10491.7 MSTRG.22211.1_1 - 3.2e-44 151.0 0.2 4.3e-44 150.6 0.2 1.2 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 LRRFIP PF09738.7 MSTRG.94022.2_3 - 2.6e-16 59.9 5.7 3.2e-16 59.6 5.7 1.1 1 0 0 1 1 1 1 LRRFIP family WD40 PF00400.30 MSTRG.137373.1_3 - 5.8e-21 74.3 1.4 4.4e-07 30.4 0.1 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 MSTRG.137373.1_3 - 4e-08 33.3 0.0 0.0038 17.3 0.0 3.4 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 MSTRG.137373.1_3 - 0.003 16.5 0.0 2.9 6.6 0.0 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.3 MSTRG.137373.1_3 - 0.0097 15.1 0.0 1.7 7.8 0.0 2.7 3 0 0 3 3 3 2 WD40-like domain PQQ PF01011.19 MSTRG.137373.1_3 - 0.056 13.3 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 PQQ enzyme repeat Peptidase_C1_2 PF03051.13 MSTRG.12245.1_3 - 1e-61 208.9 0.0 1.1e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family EMI PF07546.11 MSTRG.45022.1_2 - 0.00064 20.3 0.6 0.0012 19.5 0.6 1.4 1 0 0 1 1 1 1 EMI domain FlxA PF14282.4 MSTRG.45022.1_2 - 0.013 15.4 0.5 0.017 14.9 0.5 1.2 1 0 0 1 1 1 0 FlxA-like protein ATG16 PF08614.9 MSTRG.45022.1_2 - 0.016 15.3 0.3 0.019 15.0 0.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ax_dynein_light PF10211.7 MSTRG.45022.1_2 - 0.029 14.2 0.1 0.036 13.9 0.1 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4175 PF13779.4 MSTRG.45022.1_2 - 0.037 11.8 3.5 0.037 11.8 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) OmpH PF03938.12 MSTRG.45022.1_2 - 0.045 13.6 0.1 0.058 13.3 0.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CLZ PF16526.3 MSTRG.45022.1_2 - 0.053 13.7 0.8 0.079 13.2 0.8 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Paralemmin PF03285.13 MSTRG.45022.1_2 - 0.11 12.0 0.2 0.15 11.5 0.2 1.1 1 0 0 1 1 1 0 Paralemmin IF-2B PF01008.15 MSTRG.48457.1_2 - 8.1e-13 48.1 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family RRM_1 PF00076.20 MSTRG.62894.1_1 - 5.7e-11 42.0 0.0 7.1e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myosin_tail_1 PF01576.17 MSTRG.88097.1_1 - 1.3e-31 109.2 36.8 1.4e-31 109.1 36.8 1.0 1 0 0 1 1 1 1 Myosin tail CALCOCO1 PF07888.9 MSTRG.88097.1_1 - 6.2e-05 21.6 31.8 7.9e-05 21.3 31.8 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.10 MSTRG.88097.1_1 - 9.8e-05 21.8 6.5 0.0076 15.5 1.0 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein TSNAXIP1_N PF15739.3 MSTRG.88097.1_1 - 0.00012 22.3 21.0 0.003 17.8 5.8 3.3 2 1 1 3 3 3 2 Translin-associated factor X-interacting N-terminus Spc7 PF08317.9 MSTRG.88097.1_1 - 0.00073 18.4 37.1 0.0059 15.4 23.0 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Bacillus_HBL PF05791.9 MSTRG.88097.1_1 - 0.0009 18.9 18.4 0.5 9.9 1.0 3.3 2 1 1 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) Filament PF00038.19 MSTRG.88097.1_1 - 0.0011 18.5 32.1 0.018 14.5 32.0 2.0 1 1 0 1 1 1 1 Intermediate filament protein NEP PF10167.7 MSTRG.88097.1_1 - 0.0011 18.7 13.6 0.65 9.8 0.7 3.2 1 1 2 3 3 3 2 Uncharacterised conserved protein Tropomyosin PF00261.18 MSTRG.88097.1_1 - 0.0014 17.9 37.2 0.0018 17.6 22.0 2.1 1 1 1 2 2 2 1 Tropomyosin EzrA PF06160.10 MSTRG.88097.1_1 - 0.0014 16.7 31.1 0.0092 14.1 13.1 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA ADIP PF11559.6 MSTRG.88097.1_1 - 0.0016 18.4 36.6 0.022 14.7 9.2 3.5 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding DUF1664 PF07889.10 MSTRG.88097.1_1 - 0.0021 17.9 22.0 0.018 14.9 5.4 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) ATG16 PF08614.9 MSTRG.88097.1_1 - 0.0036 17.4 37.8 0.016 15.3 21.4 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.10 MSTRG.88097.1_1 - 0.004 17.1 21.1 0.14 12.2 2.6 4.2 1 1 3 4 4 4 1 MbeD/MobD like T3SSipB PF16535.3 MSTRG.88097.1_1 - 0.0042 17.4 7.7 0.0042 17.4 7.7 2.2 1 1 1 2 2 2 1 Type III cell invasion protein SipB DUF3450 PF11932.6 MSTRG.88097.1_1 - 0.0056 15.9 32.1 0.21 10.7 15.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Sec2p PF06428.9 MSTRG.88097.1_1 - 0.0059 16.4 38.5 0.036 13.9 9.9 3.3 1 1 2 3 3 3 2 GDP/GTP exchange factor Sec2p TMPIT PF07851.11 MSTRG.88097.1_1 - 0.0059 15.8 26.2 0.014 14.5 12.1 2.0 1 1 1 2 2 2 1 TMPIT-like protein TolA_bind_tri PF16331.3 MSTRG.88097.1_1 - 0.0063 16.4 23.1 0.018 15.0 2.3 4.3 1 1 3 4 4 4 2 TolA binding protein trimerisation WEMBL PF05701.9 MSTRG.88097.1_1 - 0.0078 14.8 36.4 0.0092 14.5 36.4 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light BBP1_C PF15272.4 MSTRG.88097.1_1 - 0.0086 15.8 14.8 0.0086 15.8 14.8 2.1 1 1 1 2 2 2 1 Spindle pole body component BBP1, C-terminal HALZ PF02183.16 MSTRG.88097.1_1 - 0.01 15.9 8.4 0.021 14.9 3.9 4.9 4 1 1 5 5 3 0 Homeobox associated leucine zipper DUF745 PF05335.11 MSTRG.88097.1_1 - 0.011 15.3 14.3 0.011 15.3 14.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.7 MSTRG.88097.1_1 - 0.011 15.6 40.7 0.047 13.6 24.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5082 PF16888.3 MSTRG.88097.1_1 - 0.012 15.9 12.8 0.012 15.9 12.8 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DUF4795 PF16043.3 MSTRG.88097.1_1 - 0.014 14.9 30.6 0.026 14.0 30.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TPR_MLP1_2 PF07926.10 MSTRG.88097.1_1 - 0.017 15.1 46.4 0.61 10.0 12.4 3.5 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein APG6 PF04111.10 MSTRG.88097.1_1 - 0.017 14.4 41.0 0.18 11.1 25.4 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Prominin PF05478.9 MSTRG.88097.1_1 - 0.018 12.9 17.7 0.032 12.1 17.7 1.4 1 1 0 1 1 1 0 Prominin KASH_CCD PF14662.4 MSTRG.88097.1_1 - 0.021 14.5 37.4 0.012 15.3 24.0 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH IncA PF04156.12 MSTRG.88097.1_1 - 0.024 14.3 43.1 0.27 10.9 23.9 2.9 1 1 2 3 3 3 0 IncA protein GAS PF13851.4 MSTRG.88097.1_1 - 0.024 13.9 37.3 0.12 11.6 12.2 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding BST2 PF16716.3 MSTRG.88097.1_1 - 0.025 15.0 8.9 0.025 15.0 8.9 4.1 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 Fib_alpha PF08702.8 MSTRG.88097.1_1 - 0.032 14.3 21.5 0.083 12.9 9.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.18 MSTRG.88097.1_1 - 0.032 14.1 38.9 0.14 12.0 4.8 4.3 1 1 3 4 4 4 0 Prefoldin subunit Syntaxin-6_N PF09177.9 MSTRG.88097.1_1 - 0.032 14.6 26.7 0.18 12.2 5.9 3.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Sec34 PF04136.13 MSTRG.88097.1_1 - 0.038 13.8 20.3 0.22 11.3 7.2 2.5 1 1 2 3 3 3 0 Sec34-like family Laminin_I PF06008.12 MSTRG.88097.1_1 - 0.045 13.3 30.2 0.66 9.5 30.2 2.0 1 1 0 1 1 1 0 Laminin Domain I DUF4201 PF13870.4 MSTRG.88097.1_1 - 0.06 12.8 30.7 0.02 14.4 14.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Uso1_p115_C PF04871.11 MSTRG.88097.1_1 - 0.063 13.5 43.4 0.15 12.3 10.3 3.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region RPW8 PF05659.9 MSTRG.88097.1_1 - 0.065 12.8 14.1 0.055 13.0 5.1 2.5 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Hormone_1 PF00103.18 MSTRG.88097.1_1 - 0.077 12.6 9.6 1.1 8.8 2.2 2.3 1 1 0 2 2 2 0 Somatotropin hormone family WXG100 PF06013.10 MSTRG.88097.1_1 - 0.079 13.1 21.9 0.051 13.7 2.9 4.3 2 1 0 3 3 3 0 Proteins of 100 residues with WXG Phage_GP20 PF06810.9 MSTRG.88097.1_1 - 0.082 12.6 32.2 0.026 14.2 6.9 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 TelA PF05816.9 MSTRG.88097.1_1 - 0.092 11.7 25.8 0.02 13.9 14.8 2.2 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) Pox_A_type_inc PF04508.10 MSTRG.88097.1_1 - 0.094 12.5 1.6 22 5.0 0.3 3.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3584 PF12128.6 MSTRG.88097.1_1 - 0.1 10.0 35.1 0.19 9.1 35.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.10 MSTRG.88097.1_1 - 0.11 12.3 13.2 3.5 7.5 2.0 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG6 PF06419.9 MSTRG.88097.1_1 - 0.12 10.5 25.4 0.14 10.2 9.3 2.5 1 1 2 3 3 3 0 Conserved oligomeric complex COG6 HAUS-augmin3 PF14932.4 MSTRG.88097.1_1 - 0.15 11.4 33.2 0.27 10.6 15.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Mce4_CUP1 PF11887.6 MSTRG.88097.1_1 - 0.15 11.3 2.1 0.25 10.6 0.9 1.7 1 1 0 2 2 1 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.9 MSTRG.88097.1_1 - 0.16 12.1 13.5 0.69 10.1 0.6 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-H PF05837.10 MSTRG.88097.1_1 - 0.18 12.1 31.0 0.33 11.2 11.2 2.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ERM PF00769.17 MSTRG.88097.1_1 - 0.22 11.2 43.5 1.9 8.1 24.5 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Tubulin-binding PF00418.17 MSTRG.88097.1_1 - 0.25 11.3 0.4 1.1 9.2 0.1 2.1 2 0 0 2 2 1 0 Tau and MAP protein, tubulin-binding repeat PspA_IM30 PF04012.10 MSTRG.88097.1_1 - 0.3 10.5 34.4 3.4 7.0 33.6 2.5 1 1 0 1 1 1 0 PspA/IM30 family Tropomyosin_1 PF12718.5 MSTRG.88097.1_1 - 0.32 11.0 42.9 1.5 8.8 24.6 3.1 1 1 2 3 3 3 0 Tropomyosin like DUF724 PF05266.12 MSTRG.88097.1_1 - 0.32 10.6 33.6 0.049 13.3 12.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2205 PF10224.7 MSTRG.88097.1_1 - 0.33 10.8 22.3 0.044 13.6 1.8 3.3 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) TMF_TATA_bd PF12325.6 MSTRG.88097.1_1 - 0.35 11.0 37.4 0.079 13.1 6.3 3.8 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Sulfatase_C PF14707.4 MSTRG.88097.1_1 - 0.38 11.4 13.8 0.42 11.2 1.0 3.6 1 1 2 3 3 3 0 C-terminal region of aryl-sulfatase Kinetocho_Slk19 PF12709.5 MSTRG.88097.1_1 - 0.39 11.0 32.8 0.13 12.5 1.9 5.1 1 1 4 5 5 4 0 Central kinetochore-associated AAA_13 PF13166.4 MSTRG.88097.1_1 - 0.42 9.1 29.1 2.1 6.7 29.1 1.8 1 1 0 1 1 1 0 AAA domain Lebercilin PF15619.4 MSTRG.88097.1_1 - 0.43 10.1 37.8 1.3 8.5 18.5 2.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.10 MSTRG.88097.1_1 - 0.5 8.3 34.4 2.6 6.0 17.2 2.2 1 1 1 2 2 2 0 HOOK protein Sec20 PF03908.11 MSTRG.88097.1_1 - 0.53 10.1 15.8 0.21 11.4 0.7 3.6 1 1 3 4 4 4 0 Sec20 DUF812 PF05667.9 MSTRG.88097.1_1 - 0.57 8.9 36.0 1.2 7.9 24.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FPP PF05911.9 MSTRG.88097.1_1 - 0.61 8.1 35.7 0.085 11.0 18.7 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil BLOC1_2 PF10046.7 MSTRG.88097.1_1 - 0.78 10.0 22.6 0.31 11.2 5.4 3.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HemX PF04375.12 MSTRG.88097.1_1 - 0.79 8.8 33.3 0.15 11.2 7.5 3.0 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cluap1 PF10234.7 MSTRG.88097.1_1 - 0.8 8.9 31.7 0.02 14.1 8.4 2.9 1 1 2 3 3 3 0 Clusterin-associated protein-1 OmpH PF03938.12 MSTRG.88097.1_1 - 0.84 9.5 42.4 1.1 9.1 11.5 3.2 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Med9 PF07544.11 MSTRG.88097.1_1 - 0.86 9.6 26.3 1.3 9.0 6.8 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fez1 PF06818.13 MSTRG.88097.1_1 - 0.87 9.9 34.2 5.1e+02 0.8 33.0 2.2 1 1 0 1 1 1 0 Fez1 Laminin_II PF06009.10 MSTRG.88097.1_1 - 0.96 9.3 24.4 1.2 9.0 5.6 3.2 1 1 2 3 3 3 0 Laminin Domain II DivIC PF04977.13 MSTRG.88097.1_1 - 1 9.0 32.4 0.92 9.2 2.0 5.0 1 1 3 5 5 5 0 Septum formation initiator COG2 PF06148.9 MSTRG.88097.1_1 - 1 9.3 22.1 4.7 7.2 5.2 3.4 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.11 MSTRG.88097.1_1 - 1 9.9 27.2 5.5 7.5 5.1 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TACC PF05010.12 MSTRG.88097.1_1 - 1.1 8.9 35.3 5.3 6.6 9.8 3.2 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Mnd1 PF03962.13 MSTRG.88097.1_1 - 1.1 8.9 41.4 2.6 7.7 9.9 3.0 1 1 1 2 2 2 0 Mnd1 family NPV_P10 PF05531.10 MSTRG.88097.1_1 - 1.2 9.5 8.8 27 5.2 0.4 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.19 MSTRG.88097.1_1 - 1.2 8.8 16.5 0.51 9.9 4.0 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF16 PF01519.14 MSTRG.88097.1_1 - 1.2 9.5 21.6 0.75 10.2 6.4 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.6 MSTRG.88097.1_1 - 1.3 9.0 44.0 0.057 13.3 5.0 4.3 1 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding IFT57 PF10498.7 MSTRG.88097.1_1 - 1.4 7.7 29.0 1.3 7.8 15.7 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF932 PF06067.9 MSTRG.88097.1_1 - 1.4 8.5 18.4 1.1 8.8 12.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF932) Golgin_A5 PF09787.7 MSTRG.88097.1_1 - 1.5 8.1 35.5 1.3 8.3 17.1 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.3 MSTRG.88097.1_1 - 1.5 9.4 37.8 4.2 7.9 10.7 3.4 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.20 MSTRG.88097.1_1 - 1.5 8.9 34.3 0.26 11.4 8.7 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4600 PF15372.4 MSTRG.88097.1_1 - 1.7 9.0 32.4 2.3e+02 2.0 17.7 4.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) DUF3734 PF12536.6 MSTRG.88097.1_1 - 1.7 8.9 9.2 3.8 7.8 0.8 3.0 1 1 3 4 4 2 0 Patatin phospholipase PRKG1_interact PF15898.3 MSTRG.88097.1_1 - 1.8 9.4 34.8 3.8 8.3 17.7 3.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain HMMR_N PF15905.3 MSTRG.88097.1_1 - 1.8 7.8 38.1 48 3.1 37.8 2.3 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.4 MSTRG.88097.1_1 - 1.9 7.7 27.5 0.69 9.1 13.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.11 MSTRG.88097.1_1 - 2.2 8.9 21.1 6.8 7.3 2.9 3.3 1 1 2 3 3 3 0 Occludin homology domain CC2-LZ PF16516.3 MSTRG.88097.1_1 - 2.5 8.3 33.2 0.84 9.9 6.9 3.6 1 1 3 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Prefoldin PF02996.15 MSTRG.88097.1_1 - 2.8 7.8 31.8 0.16 11.7 2.1 4.9 1 1 6 7 7 7 0 Prefoldin subunit CwsA PF10814.6 MSTRG.88097.1_1 - 2.9 7.9 6.9 2.7 8.0 4.3 2.2 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA IFT46_B_C PF12317.6 MSTRG.88097.1_1 - 3.2 7.3 13.8 0.18 11.4 5.9 2.3 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Exonuc_VII_L PF02601.13 MSTRG.88097.1_1 - 3.3 7.0 26.6 2.1e+02 1.1 26.6 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit ISG65-75 PF11727.6 MSTRG.88097.1_1 - 3.7 6.6 29.7 0.99 8.4 5.8 3.0 1 1 2 3 3 3 0 Invariant surface glycoprotein BRE1 PF08647.9 MSTRG.88097.1_1 - 4.8 7.2 40.1 0.24 11.3 15.7 3.7 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase Nup54 PF13874.4 MSTRG.88097.1_1 - 4.9 7.1 25.6 1.4 8.9 6.4 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 FliD_N PF02465.16 MSTRG.88097.1_1 - 6 7.5 17.7 37 5.0 2.1 3.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FAM76 PF16046.3 MSTRG.88097.1_1 - 6.1 6.0 25.8 0.67 9.1 20.6 1.8 1 1 1 2 2 2 0 FAM76 protein Tweety PF04906.11 MSTRG.88097.1_1 - 6.4 5.2 9.1 10 4.5 1.9 2.2 1 1 1 2 2 2 0 Tweety CDPS PF16715.3 MSTRG.88097.1_1 - 6.9 6.1 14.1 0.68 9.4 2.8 3.0 1 1 2 3 3 3 0 Cyclodipeptide synthase Leu_zip PF15294.4 MSTRG.88097.1_1 - 8.3 5.7 32.5 5.8 6.2 15.5 2.1 1 1 1 2 2 2 0 Leucine zipper FlaC_arch PF05377.9 MSTRG.88097.1_1 - 8.4 6.7 25.7 6.4 7.1 1.4 4.9 2 2 3 5 5 4 0 Flagella accessory protein C (FlaC) YojJ PF10372.7 MSTRG.88097.1_1 - 8.8 6.4 17.0 5.1 7.1 1.0 4.2 1 1 4 5 5 5 0 Bacterial membrane-spanning protein N-terminus Pro_Al_protease PF02983.12 MSTRG.88097.1_1 - 8.8 6.3 7.8 24 4.9 1.1 3.6 3 1 1 4 4 2 0 Alpha-lytic protease prodomain PSI_PsaF PF02507.13 MSTRG.88097.1_1 - 8.9 6.0 7.5 1.2 8.9 2.0 2.2 1 1 1 2 2 2 0 Photosystem I reaction centre subunit III FH2 PF02181.21 MSTRG.88097.1_1 - 9 5.2 26.7 2.1 7.3 5.7 3.0 1 1 2 3 3 3 0 Formin Homology 2 Domain Rdx PF10262.7 MSTRG.77847.1_3 - 4.5e-11 42.6 0.0 7.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Rdx family Reprolysin_5 PF13688.4 MSTRG.15453.1_3 - 0.0015 18.6 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 DUF1168 PF06658.10 MSTRG.15453.1_3 - 0.0088 15.7 2.6 0.11 12.2 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Zip PF02535.20 MSTRG.15453.1_3 - 0.034 13.2 0.1 0.039 13.0 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Reprolysin PF01421.17 MSTRG.15453.1_3 - 0.088 12.6 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease SAM_decarbox PF01536.14 MSTRG.15453.1_3 - 0.12 11.2 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase DUF3915 PF13054.4 MSTRG.15453.1_3 - 0.14 12.0 0.3 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) LRR_6 PF13516.4 MSTRG.53863.1_1 - 6.6e-15 53.7 3.4 0.0006 19.5 0.0 5.2 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.5 MSTRG.53863.1_1 - 0.021 15.1 2.3 6.8 7.1 0.1 3.1 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) 5_nucleotid PF05761.12 MSTRG.143365.1_3 - 1.6e-95 320.6 0.0 1.8e-95 320.4 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.4 MSTRG.143365.1_3 - 0.17 11.9 0.0 0.62 10.0 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase IncA PF04156.12 MSTRG.6657.1_2 - 0.37 10.4 4.0 0.43 10.2 4.0 1.0 1 0 0 1 1 1 0 IncA protein PDEase_I PF00233.17 MSTRG.110911.1_3 - 2.4e-17 63.4 0.4 2.6e-17 63.2 0.4 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF4559 PF15112.4 MSTRG.110911.1_3 - 0.013 15.0 0.3 0.015 14.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) GSHPx PF00255.17 MSTRG.110911.1_3 - 0.048 13.1 0.0 0.055 12.9 0.0 1.0 1 0 0 1 1 1 0 Glutathione peroxidase NIF PF03031.16 MSTRG.51026.1_2 - 1.7e-31 108.9 0.0 2.5e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DDE_3 PF13358.4 MSTRG.91053.1_3 - 0.00013 21.6 0.1 0.0002 21.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.20 MSTRG.90909.1_2 - 3.5e-29 101.7 0.0 4.6e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 I-set PF07679.14 MSTRG.108830.1_3 - 9.9e-12 44.6 0.0 2.2e-05 24.3 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.108830.1_3 - 5.4e-10 39.6 0.1 3.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 MSTRG.108830.1_3 - 1.4e-07 31.5 0.0 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.108830.1_3 - 2.8e-06 27.4 0.0 0.0038 17.4 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 MSTRG.108830.1_3 - 1.5e-05 25.0 0.0 0.003 17.6 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin V-set domain Izumo-Ig PF16706.3 MSTRG.108830.1_3 - 0.097 12.6 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_5 PF16681.3 MSTRG.108830.1_3 - 0.14 12.4 0.0 7.3 7.0 0.0 2.0 1 1 1 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF3915 PF13054.4 MSTRG.105738.1_1 - 5.4 6.9 9.4 9.3 6.1 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3915 PF13054.4 MSTRG.105738.1_3 - 0.97 9.3 7.7 1.6 8.6 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF2635 PF10948.6 MSTRG.77980.1_1 - 5.8 6.6 8.2 1.2e+02 2.3 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF2635) GIT_SHD PF08518.9 MSTRG.77980.1_2 - 7.5e-07 28.5 0.0 27 4.4 0.0 5.5 6 0 0 6 6 6 5 Spa2 homology domain (SHD) of GIT UBA_3 PF09288.8 MSTRG.77980.1_2 - 0.0048 16.5 4.3 15 5.4 0.1 4.1 1 1 4 5 5 5 5 Fungal ubiquitin-associated domain PXT1 PF15214.4 MSTRG.77980.1_2 - 0.17 12.2 0.7 6.7 7.0 0.0 2.7 1 1 1 3 3 3 0 Peroxisomal testis-specific protein 1 zf-H2C2_2 PF13465.4 MSTRG.90444.1_2 - 2.7e-17 62.2 12.6 3.7e-08 33.3 0.3 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.90444.1_2 - 7e-13 48.1 13.9 4.5e-08 33.0 1.4 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.90444.1_2 - 1.4e-07 31.6 11.3 0.0001 22.7 0.8 2.6 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.4 MSTRG.90444.1_2 - 3.6e-07 29.9 11.7 0.0014 18.4 1.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger CpXC PF14353.4 MSTRG.90444.1_2 - 0.001 18.9 4.1 0.0059 16.5 1.9 2.0 1 1 0 1 1 1 1 CpXC protein zf-C2H2_jaz PF12171.6 MSTRG.90444.1_2 - 0.0015 18.7 12.7 0.079 13.2 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DZR PF12773.5 MSTRG.90444.1_2 - 0.002 18.0 1.7 0.003 17.4 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.17 MSTRG.90444.1_2 - 0.0041 17.0 1.4 0.0051 16.7 1.4 1.3 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-met PF12874.5 MSTRG.90444.1_2 - 0.007 16.6 2.9 0.007 16.6 2.9 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.8 MSTRG.90444.1_2 - 0.008 16.2 4.0 0.018 15.0 3.1 1.9 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2H2_11 PF16622.3 MSTRG.90444.1_2 - 0.013 15.1 12.3 0.34 10.6 3.8 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-LYAR PF08790.9 MSTRG.90444.1_2 - 0.035 13.9 8.5 0.47 10.3 2.5 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger C1-set PF07654.13 MSTRG.90444.1_2 - 0.069 13.5 3.0 1.3 9.4 0.3 2.0 1 1 1 2 2 2 0 Immunoglobulin C1-set domain DUF3268 PF11672.6 MSTRG.90444.1_2 - 0.099 12.9 4.4 0.059 13.6 2.8 1.5 1 1 0 1 1 1 0 zinc-finger-containing domain SRCR PF00530.16 MSTRG.13140.1_2 - 1.6e-50 169.6 12.3 1.7e-29 102.1 4.4 2.2 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.4 MSTRG.13140.1_2 - 4.8e-11 42.9 4.3 4.1e-05 23.9 0.9 2.7 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.8 MSTRG.13140.1_2 - 0.0028 17.8 0.4 2.2 8.5 0.1 3.2 2 1 1 3 3 3 2 Hepsin, SRCR CaMKII_AD PF08332.8 MSTRG.90384.1_1 - 4.7e-60 201.2 0.0 7e-60 200.7 0.0 1.2 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.4 MSTRG.90384.1_1 - 1e-08 35.4 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.4 MSTRG.90384.1_1 - 1.5e-08 34.8 0.0 2.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lipoxygenase PF00305.17 MSTRG.37398.1_1 - 0.00046 18.6 0.2 0.00049 18.5 0.2 1.0 1 0 0 1 1 1 1 Lipoxygenase RVT_1 PF00078.25 MSTRG.103364.1_2 - 3.7e-08 33.0 0.0 6.2e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sulfatase PF00884.21 MSTRG.72851.1_2 - 2.1e-32 112.6 0.4 2.4e-32 112.4 0.4 1.0 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.15 MSTRG.72851.1_2 - 0.00014 20.5 0.0 0.00018 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Collagen PF01391.16 MSTRG.85578.1_3 - 3.3e-07 29.8 39.5 0.00056 19.5 21.4 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Rhomboid_SP PF12595.6 MSTRG.38328.1_3 - 9.1e-06 25.1 0.2 1.2e-05 24.6 0.1 1.4 1 1 0 1 1 1 1 Rhomboid serine protease Phostensin PF13914.4 MSTRG.115980.1_3 - 2.1e-30 106.0 2.7 2.1e-30 106.0 2.7 2.6 1 1 0 2 2 2 1 Phostensin PP1-binding and SH3-binding region PAT1 PF09770.7 MSTRG.115980.1_3 - 7.1 4.6 16.2 9.2 4.3 16.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Thioredoxin PF00085.18 MSTRG.27752.2_3 - 5.2e-09 35.8 0.0 9.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Peptidase_S9 PF00326.19 MSTRG.34416.1_2 - 2.5e-14 53.1 0.1 6.2e-14 51.8 0.2 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DPPIV_N PF00930.19 MSTRG.34416.1_2 - 7.7e-11 41.2 0.2 9.8e-11 40.9 0.2 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF4575 PF15143.4 MSTRG.27056.1_1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4575) Peptidase_S8 PF00082.20 MSTRG.27056.1_3 - 6.9e-07 28.7 0.0 8e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 Subtilase family RVT_1 PF00078.25 MSTRG.62710.1_2 - 0.003 17.0 0.0 0.0033 16.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH PF00169.27 MSTRG.55627.1_1 - 4.6e-33 113.8 13.8 5.6e-17 62.0 0.2 4.3 3 1 1 4 4 4 4 PH domain PH_3 PF14593.4 MSTRG.55627.1_1 - 1.4e-12 47.4 2.4 1.4e-08 34.6 0.2 3.2 2 1 1 3 3 3 2 PH domain PH_8 PF15409.4 MSTRG.55627.1_1 - 2.6e-12 46.7 3.0 8.4e-08 32.3 0.2 3.5 3 0 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.4 MSTRG.55627.1_1 - 1.5e-08 34.8 24.5 0.0026 18.0 6.9 5.3 2 2 1 3 3 3 3 Pleckstrin homology domain PH_9 PF15410.4 MSTRG.55627.1_1 - 0.014 15.6 2.5 0.19 12.0 1.0 3.1 1 1 1 2 2 2 0 Pleckstrin homology domain NKAP PF15692.3 MSTRG.135944.1_2 - 2e-12 47.5 13.0 2e-12 47.5 13.0 3.3 1 1 2 3 3 3 1 NF-kappa-B-activating protein DDHD PF02862.15 MSTRG.135944.1_2 - 2 8.4 10.2 2.5 8.0 10.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF3585 PF12130.6 MSTRG.35655.1_2 - 1.9e-48 163.9 27.4 1.9e-48 163.9 27.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3585) Glycos_transf_N PF04413.14 MSTRG.35655.1_3 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Integrin_alpha PF00357.18 MSTRG.111811.1_1 - 0.0021 17.8 0.3 0.0031 17.3 0.3 1.3 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region DUF1673 PF07895.9 MSTRG.111811.1_1 - 0.029 13.9 0.2 0.031 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF4006 PF13179.4 MSTRG.111811.1_1 - 0.058 13.2 0.4 0.08 12.7 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF4446 PF14584.4 MSTRG.111811.1_1 - 0.11 12.3 0.4 0.15 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2207 PF09972.7 MSTRG.111811.1_1 - 0.16 10.5 0.2 0.16 10.6 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Vpu PF00558.17 MSTRG.111811.1_1 - 0.2 11.3 1.5 0.26 11.0 1.5 1.2 1 0 0 1 1 1 0 Vpu protein DUF778 PF05608.10 MSTRG.24865.1_1 - 1.9e-24 86.9 0.2 2.2e-24 86.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF778) RVT_1 PF00078.25 MSTRG.37356.1_2 - 6.8e-10 38.7 0.2 8.1e-10 38.4 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DRAT PF07357.9 MSTRG.37356.1_2 - 0.062 12.3 0.2 0.084 11.9 0.2 1.2 1 1 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Phage_TAC_4 PF08748.9 MSTRG.37356.1_2 - 0.066 13.4 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Phage tail assembly chaperone Enterotoxin_HS1 PF08090.9 MSTRG.81846.1_1 - 0.097 12.5 1.3 0.16 11.8 1.3 1.3 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 GATase PF00117.26 MSTRG.27786.1_1 - 0.00091 18.9 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.11 MSTRG.27786.1_1 - 0.0073 15.9 0.0 0.0087 15.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C26 zf-DHHC PF01529.18 MSTRG.31975.1_1 - 0.07 13.1 0.2 0.07 13.1 0.2 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase Rad50_zn_hook PF04423.12 MSTRG.123624.1_2 - 0.0012 18.6 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-C2H2_4 PF13894.4 MSTRG.123624.1_2 - 0.036 14.8 0.0 0.075 13.8 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Antistasin PF02822.12 MSTRG.51808.1_2 - 0.02 15.4 0.9 14 6.3 0.0 3.1 2 1 0 2 2 2 0 Antistasin family mRNA_decap_C PF16741.3 MSTRG.1370.1_1 - 0.093 11.9 0.0 13 5.0 0.0 3.1 3 0 0 3 3 3 0 mRNA-decapping enzyme C-terminus zf-H2C2_2 PF13465.4 MSTRG.111725.1_1 - 1.5e-17 63.0 34.4 6.7e-07 29.3 0.3 5.7 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.24 MSTRG.111725.1_1 - 1.6e-16 59.6 35.5 3.1e-05 24.1 2.3 5.2 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 MSTRG.111725.1_1 - 2.9e-14 52.4 32.1 0.00046 20.7 2.2 4.8 5 1 0 5 5 4 4 C2H2-type zinc finger zf-C2HC_2 PF13913.4 MSTRG.111725.1_1 - 1.5e-08 34.2 17.6 0.01 15.6 1.4 4.4 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.3 MSTRG.111725.1_1 - 0.0001 21.9 7.3 0.00079 19.0 0.8 4.1 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.3 MSTRG.111725.1_1 - 0.00011 22.3 14.1 0.0044 17.2 2.5 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon PyrI_C PF02748.13 MSTRG.111725.1_1 - 0.00012 21.8 6.1 0.26 11.1 0.8 3.2 3 0 0 3 3 3 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.4 MSTRG.111725.1_1 - 0.00017 21.3 31.7 0.00048 19.9 1.4 5.1 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 MSTRG.111725.1_1 - 0.00031 20.8 11.8 0.16 12.2 0.1 5.6 3 2 2 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-ribbon_3 PF13248.4 MSTRG.111725.1_1 - 0.0019 17.4 5.5 2.2 7.7 0.1 3.7 4 0 0 4 4 4 1 zinc-ribbon domain zf-CHCC PF10276.7 MSTRG.111725.1_1 - 0.0019 18.1 13.7 0.21 11.6 0.0 3.5 4 0 0 4 4 3 2 Zinc-finger domain zf-Di19 PF05605.10 MSTRG.111725.1_1 - 0.0053 16.9 14.2 0.038 14.2 6.2 2.7 1 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding DUF2256 PF10013.7 MSTRG.111725.1_1 - 0.0064 16.4 9.2 8.7 6.4 0.0 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Peptidase_C16 PF01831.15 MSTRG.111725.1_1 - 0.011 15.3 0.4 0.013 15.1 0.4 1.2 1 0 0 1 1 1 0 Peptidase C16 family zf-met PF12874.5 MSTRG.111725.1_1 - 0.029 14.6 25.2 0.55 10.5 1.3 4.9 6 0 0 6 6 4 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.3 MSTRG.111725.1_1 - 0.035 14.7 8.4 0.061 13.9 0.4 2.3 1 1 1 2 2 2 0 zinc-ribbon family HNH PF01844.21 MSTRG.111725.1_1 - 0.059 13.4 13.1 2.4 8.2 0.2 4.3 4 0 0 4 4 4 0 HNH endonuclease YyzF PF14116.4 MSTRG.111725.1_1 - 0.14 12.1 6.7 5.1 7.1 0.1 3.3 3 1 0 3 3 3 0 YyzF-like protein Zn_ribbon_recom PF13408.4 MSTRG.111725.1_1 - 0.18 12.2 13.9 0.55 10.7 0.1 3.3 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-C2H2_2 PF12756.5 MSTRG.111725.1_1 - 0.25 11.5 21.0 3.4 7.9 0.5 3.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RING_7 PF02591.13 MSTRG.111725.1_1 - 0.37 10.9 6.2 2.2 8.4 0.1 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-C2HE PF16278.3 MSTRG.111725.1_1 - 2.2 8.7 20.0 23 5.4 2.5 4.0 2 2 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.19 MSTRG.111725.1_1 - 2.3 8.3 21.9 6.3e+03 -2.7 21.9 3.3 1 1 0 1 1 1 0 FYVE zinc finger FYDLN_acid PF09538.8 MSTRG.111725.1_1 - 4.3 7.9 5.6 16 6.1 0.4 3.3 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_2 PF13240.4 MSTRG.111725.1_1 - 9.4 6.0 14.1 7 6.4 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain PGM_PMM_III PF02880.14 MSTRG.43759.2_1 - 1.6e-31 108.7 0.0 2.4e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.18 MSTRG.43759.2_1 - 2e-06 27.7 0.0 3.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPRY PF00622.26 MSTRG.38218.1_3 - 0.00059 19.8 0.0 0.00064 19.7 0.0 1.0 1 0 0 1 1 1 1 SPRY domain Anoctamin PF04547.10 MSTRG.111499.1_3 - 7.8e-07 28.1 0.2 9.7e-07 27.8 0.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Ig_3 PF13927.4 MSTRG.103280.1_1 - 0.00011 22.6 0.5 0.00018 21.9 0.5 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.103280.1_1 - 0.00015 21.9 0.2 0.00024 21.2 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.3 MSTRG.103280.1_1 - 0.0083 16.4 0.4 0.015 15.6 0.4 1.4 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF3915 PF13054.4 MSTRG.2766.1_2 - 0.89 9.4 5.4 4.6 7.1 5.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) Endonuc-dimeris PF09124.8 MSTRG.2766.1_3 - 0.019 15.0 0.5 7 6.8 0.1 2.3 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation Aa_trans PF01490.16 MSTRG.91393.1_1 - 2.6e-05 23.0 2.8 2.8e-05 22.9 2.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2417 PF10329.7 MSTRG.91393.1_1 - 0.016 14.5 0.9 0.018 14.4 0.9 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Septin PF00735.16 MSTRG.77084.1_2 - 1.7e-52 178.3 0.0 2.2e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.21 MSTRG.77084.1_2 - 5.4e-08 32.8 0.0 9.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.14 MSTRG.77084.1_2 - 4.2e-05 22.8 0.0 6.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.21 MSTRG.77084.1_2 - 0.00011 22.2 0.2 0.039 13.9 0.0 2.2 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.14 MSTRG.77084.1_2 - 0.00019 21.3 0.5 0.00039 20.2 0.5 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.20 MSTRG.77084.1_2 - 0.00027 20.4 0.0 0.0005 19.6 0.0 1.5 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.25 MSTRG.77084.1_2 - 0.00054 19.4 0.0 0.0014 18.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.11 MSTRG.77084.1_2 - 0.0016 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.4 MSTRG.77084.1_2 - 0.0038 17.4 0.0 0.0078 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.25 MSTRG.77084.1_2 - 0.0055 17.1 0.0 0.008 16.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.4 MSTRG.77084.1_2 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.4 MSTRG.77084.1_2 - 0.0069 16.6 0.0 0.0083 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.10 MSTRG.77084.1_2 - 0.056 12.7 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_ATPase PF09818.7 MSTRG.77084.1_2 - 0.085 11.5 0.0 2.4 6.7 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DDE_3 PF13358.4 MSTRG.140905.1_1 - 5.2e-05 22.9 0.1 8.7e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1579 PF07617.9 MSTRG.140905.1_1 - 0.064 13.1 0.1 0.089 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1579) BTB PF00651.29 MSTRG.77208.2_1 - 2.6e-26 91.9 0.0 3.2e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.39734.1_2 - 2.4e-06 27.6 0.1 4.5e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Transposase C1-set PF07654.13 MSTRG.26490.1_3 - 0.026 14.9 0.6 0.17 12.2 0.0 1.9 1 1 1 2 2 2 0 Immunoglobulin C1-set domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.135644.1_2 - 0.0047 17.0 0.2 0.0059 16.7 0.2 1.2 1 0 0 1 1 1 1 Transposase AgrD PF05931.9 MSTRG.65708.1_3 - 0.012 15.5 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Staphylococcal AgrD protein PNPOx_C PF10590.7 MSTRG.12870.1_3 - 1.7e-19 69.5 0.7 3.3e-19 68.6 0.7 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Synaptobrevin PF00957.19 MSTRG.65927.1_3 - 4.2e-13 48.8 0.6 6e-13 48.3 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin DDE_3 PF13358.4 MSTRG.55833.1_2 - 0.0079 15.8 0.0 0.1 12.2 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Myosin_head PF00063.19 MSTRG.97885.1_2 - 1.2e-25 89.7 0.0 1.4e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Interfer-bind PF09294.8 MSTRG.59096.1_3 - 8.5e-05 22.7 1.3 0.00016 21.8 1.3 1.4 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III RIC3 PF15361.4 MSTRG.59096.1_3 - 0.0018 18.6 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 YCF90 PF17088.3 MSTRG.59096.1_3 - 0.0092 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family DUF3081 PF11280.6 MSTRG.59096.1_3 - 0.013 15.2 0.5 1.5 8.6 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3081) Gag_p17 PF00540.16 MSTRG.59096.1_3 - 0.094 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) DUF2461 PF09365.8 MSTRG.136486.1_1 - 0.11 12.2 2.9 1.9 8.2 0.7 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) YtxH PF12732.5 MSTRG.136486.1_1 - 0.14 12.6 0.3 5.6 7.4 0.1 2.5 2 1 0 2 2 2 0 YtxH-like protein DUF1098 PF06497.9 MSTRG.136486.1_1 - 0.19 12.1 0.9 6.7 7.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1098) MH2 PF03166.12 MSTRG.93795.1_1 - 6.6e-25 88.3 0.0 8.8e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 MH2 domain Cation_ATPase_C PF00689.19 MSTRG.70900.1_3 - 1e-19 70.8 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.24 MSTRG.70900.1_3 - 1.9e-14 54.3 0.1 3.1e-06 27.5 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.10 MSTRG.70900.1_3 - 1.9e-05 24.4 0.8 0.00073 19.2 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.4 MSTRG.70900.1_3 - 0.0005 20.0 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) GDA1_CD39 PF01150.15 MSTRG.113975.1_3 - 4.3e-67 226.5 0.0 1.4e-66 224.8 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.14 MSTRG.113975.1_3 - 0.032 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family NIR_SIR_ferr PF03460.15 MSTRG.95536.1_1 - 1.1 9.0 4.3 10 5.9 0.5 2.5 1 1 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain HMG14_17 PF01101.16 MSTRG.82288.1_2 - 2.1e-10 41.3 32.6 2.7e-10 40.9 32.6 1.1 1 0 0 1 1 1 1 HMG14 and HMG17 RVT_1 PF00078.25 MSTRG.23729.1_2 - 1.2e-15 57.5 0.0 1.5e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AA_synth PF06684.9 MSTRG.23729.1_2 - 0.19 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Amino acid synthesis DDE_3 PF13358.4 MSTRG.37820.1_1 - 0.043 13.4 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF4240 PF14024.4 MSTRG.109798.1_3 - 0.05 13.7 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) P34-Arc PF04045.12 MSTRG.94204.1_2 - 5e-68 229.2 1.3 5.9e-68 229.0 1.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Vps4_C PF09336.8 MSTRG.94204.1_2 - 0.096 12.6 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain GDA1_CD39 PF01150.15 MSTRG.77726.1_3 - 2.9e-66 223.8 0.0 3.4e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.14 MSTRG.77726.1_3 - 0.17 11.1 0.1 0.59 9.4 0.1 1.8 1 1 0 1 1 1 0 Ppx/GppA phosphatase family HTH_Tnp_Tc3_2 PF01498.16 MSTRG.130910.1_2 - 2.4e-17 62.8 0.2 4.9e-17 61.8 0.2 1.6 1 0 0 1 1 1 1 Transposase DUF5101 PF17031.3 MSTRG.136417.1_2 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) TLD PF07534.14 MSTRG.68801.1_1 - 2.7e-12 46.9 0.1 5e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 TLD MMR_HSR1 PF01926.21 MSTRG.68801.1_1 - 3.1e-06 27.1 0.0 5.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.15 MSTRG.68801.1_1 - 0.00076 19.2 0.5 0.85 9.2 0.1 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein DUF258 PF03193.14 MSTRG.68801.1_1 - 0.019 14.8 1.0 0.055 13.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Septin PF00735.16 MSTRG.68801.1_1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_29 PF13555.4 MSTRG.68801.1_1 - 0.021 14.4 0.0 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain G-alpha PF00503.18 MSTRG.68801.1_1 - 0.057 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit cobW PF02492.17 MSTRG.68801.1_1 - 0.098 12.1 0.5 6 6.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRCR PF00530.16 MSTRG.39799.1_3 - 6.6e-30 103.5 2.5 1.1e-29 102.8 2.5 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.4 MSTRG.39799.1_3 - 1.9e-05 25.0 0.6 3.3e-05 24.2 0.6 1.6 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.8 MSTRG.39799.1_3 - 0.037 14.2 0.1 0.051 13.8 0.1 1.2 1 0 0 1 1 1 0 Hepsin, SRCR MBOAT PF03062.17 MSTRG.3042.1_3 - 7.3e-05 22.1 1.8 0.0001 21.7 1.8 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Aldedh PF00171.20 MSTRG.139731.1_1 - 0.036 12.4 0.1 0.045 12.1 0.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Myosin_tail_1 PF01576.17 MSTRG.97884.1_1 - 3.8e-38 130.9 58.1 4.5e-38 130.6 58.1 1.0 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.7 MSTRG.97884.1_1 - 0.0011 18.9 15.1 0.0011 18.9 15.1 3.9 1 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Trimer_CC PF08954.9 MSTRG.97884.1_1 - 0.0025 17.2 0.5 0.0025 17.2 0.5 3.0 3 0 0 3 3 3 1 Trimerisation motif Lipoprotein_7 PF01540.14 MSTRG.97884.1_1 - 0.005 16.0 3.0 0.005 16.0 3.0 2.7 2 1 0 2 2 2 1 Adhesin lipoprotein Alanine_zipper PF11839.6 MSTRG.97884.1_1 - 0.024 14.8 32.0 0.4 10.9 6.1 4.8 1 1 3 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein IncA PF04156.12 MSTRG.97884.1_1 - 0.029 14.0 46.4 0.2 11.3 14.0 3.4 1 1 2 3 3 3 0 IncA protein DUF3584 PF12128.6 MSTRG.97884.1_1 - 0.033 11.6 40.1 0.044 11.2 40.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1647 PF07801.9 MSTRG.97884.1_1 - 0.06 13.0 0.5 0.13 11.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Fib_alpha PF08702.8 MSTRG.97884.1_1 - 0.16 12.0 36.1 1.2 9.2 7.7 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Filament PF00038.19 MSTRG.97884.1_1 - 0.17 11.3 47.6 0.039 13.4 17.7 3.3 1 1 2 3 3 3 0 Intermediate filament protein DUF3450 PF11932.6 MSTRG.97884.1_1 - 0.19 10.9 39.7 0.11 11.7 6.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3450) ERM PF00769.17 MSTRG.97884.1_1 - 0.54 9.9 57.5 8.4 6.0 18.5 3.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF5082 PF16888.3 MSTRG.97884.1_1 - 0.84 9.9 34.1 0.04 14.1 13.2 4.6 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF1664 PF07889.10 MSTRG.97884.1_1 - 0.9 9.4 39.5 5.1 7.0 8.9 4.5 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.10 MSTRG.97884.1_1 - 3.8 6.7 19.9 2.2 7.5 2.2 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein VWA_2 PF13519.4 MSTRG.97884.1_1 - 6.3 7.4 8.3 5.1 7.7 0.1 3.3 3 1 0 3 3 3 0 von Willebrand factor type A domain Spectrin PF00435.19 MSTRG.67427.1_2 - 1e-16 61.1 10.5 1.6e-08 34.8 2.9 2.0 2 0 0 2 2 2 2 Spectrin repeat KELK PF15796.3 MSTRG.67427.1_2 - 0.17 12.2 11.4 3 8.3 0.6 3.1 2 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Q_salvage PF10343.7 MSTRG.67427.1_2 - 0.18 11.2 4.0 0.63 9.4 1.6 2.0 1 1 1 2 2 2 0 Potential Queuosine, Q, salvage protein family DUF4200 PF13863.4 MSTRG.67427.1_2 - 0.19 12.0 9.5 0.11 12.8 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.20 MSTRG.67427.1_2 - 1.8 8.7 7.3 0.91 9.6 1.2 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MACPF PF01823.17 MSTRG.119002.1_3 - 2.5e-21 76.6 1.1 2.5e-21 76.6 1.1 1.6 1 1 1 2 2 2 1 MAC/Perforin domain IRF PF00605.15 MSTRG.77384.1_2 - 1.4e-25 89.5 1.1 1.8e-25 89.1 1.1 1.1 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor ig PF00047.23 MSTRG.6187.1_2 - 0.0065 16.5 0.1 0.0076 16.3 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 MSTRG.6187.1_2 - 0.013 16.0 0.1 0.015 15.8 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.4 MSTRG.6187.1_2 - 0.023 14.9 0.1 0.031 14.5 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Caenor_Her-1 PF09232.8 MSTRG.6187.1_2 - 0.045 13.8 0.0 0.055 13.5 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 Myosin_tail_1 PF01576.17 MSTRG.13029.2_1 - 1.3e-242 807.9 132.3 1.6e-242 807.6 132.3 1.0 1 0 0 1 1 1 1 Myosin tail ADIP PF11559.6 MSTRG.13029.2_1 - 0.00088 19.3 12.4 0.00088 19.3 12.4 6.6 1 1 5 6 6 6 1 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.10 MSTRG.13029.2_1 - 0.17 11.1 34.8 1.3 8.2 0.8 4.1 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.19 MSTRG.13029.2_1 - 2.1 7.7 117.9 3.5 7.0 28.0 3.2 1 1 2 3 3 3 0 Intermediate filament protein Myosin_head PF00063.19 MSTRG.13029.2_2 - 2.6e-241 802.4 3.9 2.6e-241 802.4 3.9 2.3 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.17 MSTRG.13029.2_2 - 2.5e-207 691.1 128.1 3.1e-207 690.7 128.1 1.1 1 0 0 1 1 1 1 Myosin tail CC2-LZ PF16516.3 MSTRG.13029.2_2 - 0.0023 18.1 16.3 0.0023 18.1 16.3 7.4 2 2 4 6 6 6 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator IQ PF00612.25 MSTRG.13029.2_2 - 0.024 14.2 0.3 0.024 14.2 0.3 3.2 3 0 0 3 3 3 0 IQ calmodulin-binding motif Reo_sigmaC PF04582.10 MSTRG.13029.2_2 - 3.6 6.8 27.9 1.1 8.4 0.6 4.2 1 1 2 4 4 4 0 Reovirus sigma C capsid protein RNase_H PF00075.22 MSTRG.123360.1_2 - 0.0089 16.1 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 RNase H YrhC PF14143.4 MSTRG.25288.1_3 - 0.021 14.7 0.0 0.11 12.5 0.1 2.1 3 0 0 3 3 3 0 YrhC-like protein DENN PF02141.19 MSTRG.31485.1_2 - 1.6e-17 63.9 0.5 1.6e-17 63.9 0.5 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.17 MSTRG.31485.1_2 - 1.3e-09 37.8 6.2 1.3e-09 37.8 6.2 2.2 3 0 0 3 3 3 1 dDENN domain RRM_1 PF00076.20 MSTRG.61527.1_2 - 2.5e-17 62.3 0.0 4.1e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 MSTRG.61527.1_2 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eRF1_2 PF03464.13 MSTRG.128327.1_1 - 2.8e-28 98.7 0.0 3.3e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 eRF1 domain 2 PHD PF00628.27 MSTRG.5544.1_1 - 3.1e-10 39.7 10.7 7.3e-10 38.5 10.7 1.7 1 0 0 1 1 1 1 PHD-finger Bd3614-deam PF14439.4 MSTRG.5544.1_1 - 0.13 12.2 3.3 5.5 6.9 0.1 2.3 1 1 1 2 2 2 0 Bd3614-like deaminase zf-HC5HC2H_2 PF13832.4 MSTRG.5544.1_1 - 0.15 12.1 6.0 0.049 13.7 2.8 1.8 2 1 0 2 2 2 0 PHD-zinc-finger like domain Terminase_GpA PF05876.10 MSTRG.5544.1_1 - 0.19 10.1 4.1 0.28 9.6 4.1 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) UPF0640 PF15114.4 MSTRG.128847.1_3 - 3e-33 113.3 2.0 4.6e-33 112.7 2.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 PIEZO PF15917.3 MSTRG.143593.1_1 - 0.79 9.0 3.3 1 8.6 3.3 1.1 1 0 0 1 1 1 0 Piezo RRM_1 PF00076.20 MSTRG.143593.1_2 - 8.5e-14 51.0 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.9 MSTRG.143593.1_2 - 0.04 13.8 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif PRP38_assoc PF12871.5 MSTRG.143593.1_2 - 0.28 11.6 23.5 0.53 10.7 23.5 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Corona_nucleoca PF00937.16 MSTRG.143593.1_2 - 0.29 10.0 7.6 0.35 9.7 7.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ras PF00071.20 MSTRG.112580.1_2 - 7e-56 188.2 0.2 8.6e-56 187.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 MSTRG.112580.1_2 - 4.3e-20 72.0 0.0 6.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 MSTRG.112580.1_2 - 4.6e-08 32.6 0.1 6.3e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 MSTRG.112580.1_2 - 0.00018 21.0 0.2 0.00033 20.1 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 MSTRG.112580.1_2 - 0.00079 19.4 0.1 0.0015 18.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.14 MSTRG.112580.1_2 - 0.0032 17.3 0.1 2.7 7.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 G-alpha PF00503.18 MSTRG.112580.1_2 - 0.024 13.7 0.0 0.052 12.6 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit UQ_con PF00179.24 MSTRG.94494.1_2 - 1.1e-53 180.6 0.0 1.3e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 MSTRG.94494.1_2 - 0.016 15.4 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.4 MSTRG.94494.1_2 - 0.057 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B DEAD PF00270.27 MSTRG.5659.1_2 - 6.1e-15 55.3 1.2 6.7e-15 55.2 1.2 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.13 MSTRG.5659.1_2 - 0.00029 20.7 0.0 0.00031 20.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.4 MSTRG.5659.1_2 - 0.0018 17.9 0.2 0.0021 17.7 0.2 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.4 MSTRG.5659.1_2 - 0.019 15.2 0.2 0.02 15.1 0.2 1.0 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.12 MSTRG.5659.1_2 - 0.088 12.7 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.19 MSTRG.5659.1_2 - 0.091 12.1 0.2 0.094 12.1 0.2 1.0 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MBT PF02820.16 MSTRG.61058.1_3 - 0.039 14.2 0.4 0.055 13.7 0.4 1.2 1 0 0 1 1 1 0 mbt repeat Elf-1_N PF12310.6 MSTRG.73907.1_3 - 2.4e-10 40.8 0.1 8.6e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Transcription factor protein N terminal AAA PF00004.27 MSTRG.7643.2_3 - 1.8e-05 25.1 0.0 3.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) N2227 PF07942.10 MSTRG.7643.2_3 - 0.035 13.2 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 N2227-like protein DUF2570 PF10828.6 MSTRG.115897.1_2 - 2.6 7.8 9.6 4.5 7.1 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) I_LWEQ PF01608.15 MSTRG.115897.1_2 - 6.6 6.8 9.6 9.8 6.3 9.6 1.3 1 0 0 1 1 1 0 I/LWEQ domain Peptidase_M10 PF00413.22 MSTRG.107360.1_2 - 5.3e-41 140.0 0.0 7.3e-41 139.5 0.0 1.2 1 0 0 1 1 1 1 Matrixin fn2 PF00040.17 MSTRG.107360.1_2 - 3.8e-17 62.2 6.4 3.8e-17 62.2 6.4 2.1 2 0 0 2 2 2 1 Fibronectin type II domain PG_binding_1 PF01471.16 MSTRG.107360.1_2 - 1.1e-10 41.5 0.3 2.6e-10 40.2 0.3 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Choline_kinase PF01633.18 MSTRG.22913.1_2 - 4.6e-67 225.6 0.0 5.6e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.21 MSTRG.22913.1_2 - 5.5e-09 36.2 0.0 6.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.18 MSTRG.22913.1_2 - 0.0016 17.7 0.1 0.0028 16.9 0.1 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase ssDNA-exonuc_C PF10141.7 MSTRG.22913.1_2 - 0.0097 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Single-strand DNA-specific exonuclease, C terminal domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.133112.1_3 - 1.1e-12 47.9 1.6 1.3e-12 47.6 0.6 1.7 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.4 MSTRG.133112.1_3 - 3.8e-05 24.1 0.2 9.7e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain COX7C PF02935.14 MSTRG.54211.1_3 - 1.9e-24 85.5 1.7 3.6e-24 84.6 1.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Preseq_ALAS PF09029.8 MSTRG.32585.2_3 - 2.7e-42 143.8 6.3 3.3e-42 143.5 6.3 1.1 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence DUF515 PF04415.10 MSTRG.113036.1_3 - 3.1 5.9 7.1 7 4.8 7.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RRM_1 PF00076.20 MSTRG.38974.1_2 - 1.9e-10 40.3 0.2 1.5e-05 24.6 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1932 PF09130.9 MSTRG.38974.1_2 - 0.0073 16.1 0.3 0.038 13.8 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1932) RRM_7 PF16367.3 MSTRG.38974.1_2 - 0.0085 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif CPSF100_C PF13299.4 MSTRG.38974.1_2 - 0.093 12.8 6.8 0.31 11.1 6.8 1.9 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4140 PF13600.4 MSTRG.38974.1_2 - 0.24 11.7 0.1 0.24 11.7 0.1 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Presenilin PF01080.15 MSTRG.38974.1_2 - 1.4 7.5 3.5 1.7 7.1 3.5 1.1 1 0 0 1 1 1 0 Presenilin Cyc-maltodext_C PF10438.7 MSTRG.121216.1_1 - 0.056 13.4 0.0 35 4.5 0.0 2.9 2 1 1 3 3 3 0 Cyclo-malto-dextrinase C-terminal domain Aegerolysin PF06355.11 MSTRG.121216.1_1 - 0.068 13.1 1.2 20 5.1 0.0 2.8 3 0 0 3 3 3 0 Aegerolysin Cyc-maltodext_C PF10438.7 MSTRG.121216.1_3 - 0.0029 17.5 0.0 9.9 6.2 0.0 3.0 3 0 0 3 3 3 3 Cyclo-malto-dextrinase C-terminal domain PTS_EIIB PF00367.18 MSTRG.121216.1_3 - 0.062 12.7 0.1 60 3.1 0.0 3.0 3 0 0 3 3 3 0 phosphotransferase system, EIIB RVT_1 PF00078.25 MSTRG.44715.1_1 - 8.4e-07 28.6 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeobox PF00046.27 MSTRG.49216.1_1 - 9.1e-05 22.1 0.1 0.00014 21.5 0.1 1.3 1 0 0 1 1 1 1 Homeobox domain Carn_acyltransf PF00755.18 MSTRG.22906.1_2 - 1.3e-57 195.6 0.1 1.5e-57 195.5 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3128 PF11326.6 MSTRG.22906.1_2 - 0.0064 16.7 0.3 0.012 15.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Arf PF00025.19 MSTRG.107386.1_2 - 6.7e-09 35.3 0.0 7.3e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3788 PF12663.5 MSTRG.122611.1_3 - 1.1 9.1 5.2 3.2 7.6 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3788) ptaRNA1_toxin PF12703.5 MSTRG.122611.1_3 - 1.6 8.7 6.4 15 5.6 0.2 2.9 3 0 0 3 3 3 0 Toxin of toxin-antitoxin type 1 system DUF719 PF05334.11 MSTRG.129422.1_2 - 6.8e-64 215.5 1.6 6.8e-64 215.5 1.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF719) KIP1 PF07765.10 MSTRG.129422.1_2 - 0.9 9.6 3.9 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 KIP1-like protein Senescence PF06911.10 MSTRG.129422.1_2 - 0.96 9.5 4.6 14 5.7 0.2 2.5 2 1 0 2 2 2 0 Senescence-associated protein zf-Di19 PF05605.10 MSTRG.25990.1_3 - 2.9e-08 33.7 4.7 3.9e-08 33.3 4.7 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.4 MSTRG.25990.1_3 - 8.4e-05 22.9 7.6 0.015 15.9 0.9 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_7 PF02591.13 MSTRG.25990.1_3 - 0.0025 17.8 0.3 0.4 10.8 0.1 2.2 1 1 1 2 2 2 1 C4-type zinc ribbon domain zf-H2C2_2 PF13465.4 MSTRG.25990.1_3 - 0.0034 17.7 7.1 0.071 13.5 0.1 2.6 3 0 0 3 3 2 2 Zinc-finger double domain zf-H2C2_5 PF13909.4 MSTRG.25990.1_3 - 0.013 15.1 1.4 0.013 15.1 1.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.5 MSTRG.25990.1_3 - 0.026 14.7 4.1 0.33 11.2 0.4 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Prok-RING_4 PF14447.4 MSTRG.25990.1_3 - 0.03 14.1 0.7 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2_9 PF16293.3 MSTRG.25990.1_3 - 0.049 13.4 2.9 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.24 MSTRG.25990.1_3 - 0.086 13.2 6.9 0.31 11.5 1.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Elf1 PF05129.11 MSTRG.25990.1_3 - 0.092 12.7 3.7 4.1 7.4 0.4 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like C1_4 PF07975.10 MSTRG.25990.1_3 - 0.1 12.7 2.3 9.4 6.5 0.1 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zinc_ribbon_10 PF10058.7 MSTRG.25990.1_3 - 0.11 12.1 1.1 2.3 7.9 0.3 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Trypsin PF00089.24 MSTRG.138406.1_1 - 1.5e-48 165.4 0.1 1.6e-48 165.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 MSTRG.138406.1_1 - 3.9e-10 40.0 0.0 5.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 MSTRG.138406.1_1 - 0.00035 21.3 0.0 0.00046 20.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Focadhesin PF11229.6 MSTRG.138406.1_1 - 0.09 10.9 0.1 0.11 10.5 0.1 1.1 1 0 0 1 1 1 0 Focadhesin FAP PF07174.9 MSTRG.65388.1_1 - 7.8 5.7 19.4 1.7 7.9 6.7 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) LRRNT PF01462.16 MSTRG.110869.1_3 - 0.024 14.2 4.6 0.047 13.2 4.6 1.4 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain SMAP PF15477.4 MSTRG.66391.1_2 - 1.9e-13 51.0 1.6 3.3e-13 50.2 1.6 1.4 1 0 0 1 1 1 1 Small acidic protein family TSP_C PF05735.10 MSTRG.5024.1_2 - 1.9e-32 112.7 0.0 2.1e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Thrombospondin C-terminal region FAM222A PF15258.4 MSTRG.134496.1_1 - 0.038 13.0 12.9 0.04 12.9 12.9 1.1 1 0 0 1 1 1 0 Protein family of FAM222A CPG4 PF15481.4 MSTRG.134496.1_1 - 0.087 13.4 7.9 0.27 11.8 4.0 2.1 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 LON_substr_bdg PF02190.14 MSTRG.41942.1_1 - 1.1e-07 31.8 0.2 3.5e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain DUF4287 PF14117.4 MSTRG.41942.1_1 - 0.12 12.3 0.2 0.64 10.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4287) AAA PF00004.27 MSTRG.41942.1_3 - 4.5e-10 39.9 0.0 6.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.12 MSTRG.41942.1_3 - 1.1e-06 28.5 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 MSTRG.41942.1_3 - 1.6e-06 28.4 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.10 MSTRG.41942.1_3 - 0.00027 20.1 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.20 MSTRG.41942.1_3 - 0.0014 18.9 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.4 MSTRG.41942.1_3 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 MSTRG.41942.1_3 - 0.0051 17.2 0.0 0.0074 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.15 MSTRG.41942.1_3 - 0.015 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.20 MSTRG.41942.1_3 - 0.017 14.0 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.15 MSTRG.41942.1_3 - 0.018 14.9 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF258 PF03193.14 MSTRG.41942.1_3 - 0.022 14.5 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.4 MSTRG.41942.1_3 - 0.023 15.1 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.4 MSTRG.41942.1_3 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.10 MSTRG.41942.1_3 - 0.029 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.11 MSTRG.41942.1_3 - 0.036 12.9 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.13 MSTRG.41942.1_3 - 0.037 13.8 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 NTPase Parvo_NS1 PF01057.15 MSTRG.41942.1_3 - 0.054 12.4 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.4 MSTRG.41942.1_3 - 0.057 13.5 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.16 MSTRG.41942.1_3 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.25 MSTRG.41942.1_3 - 0.13 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.9 MSTRG.41942.1_3 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.16 MSTRG.41942.1_3 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CAP_C PF08603.9 MSTRG.48195.1_3 - 3.1e-66 221.7 4.3 3.9e-66 221.4 4.3 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.10 MSTRG.48195.1_3 - 2.5e-05 23.9 3.4 5.9e-05 22.6 3.4 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C CAP_N PF01213.17 MSTRG.48195.1_3 - 0.045 13.1 0.1 0.064 12.6 0.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cadherin_2 PF08266.10 MSTRG.24349.1_2 - 5e-21 74.2 0.0 1.5e-19 69.5 0.0 2.3 2 0 0 2 2 2 1 Cadherin-like Cadherin PF00028.15 MSTRG.24349.1_2 - 1e-19 70.6 0.0 1.6e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 Cadherin domain CytochromB561_N PF09786.7 MSTRG.8636.1_1 - 9e-51 173.4 0.1 1.1e-50 173.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal NIPSNAP PF07978.11 MSTRG.96456.2_1 - 1.5e-36 124.5 2.6 4.4e-32 110.2 0.7 2.3 2 0 0 2 2 2 2 NIPSNAP Claudin_3 PF06653.9 MSTRG.143061.1_1 - 0.0033 17.2 0.3 0.0039 17.0 0.3 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like TMEM37 PF15108.4 MSTRG.143061.1_1 - 0.016 14.9 1.6 0.019 14.7 1.6 1.1 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family Clc-like PF07062.10 MSTRG.143061.1_1 - 0.047 13.0 0.8 0.063 12.6 0.8 1.2 1 0 0 1 1 1 0 Clc-like GSG-1 PF07803.9 MSTRG.143061.1_1 - 0.53 10.1 5.3 1.2 8.9 0.9 2.2 1 1 1 2 2 2 0 GSG1-like protein SWIM PF04434.15 MSTRG.82980.1_1 - 0.13 11.9 5.9 4.5 6.9 0.1 2.5 2 1 0 2 2 2 0 SWIM zinc finger WCCH PF03716.12 MSTRG.82980.1_1 - 1 9.0 5.2 11 5.6 0.5 2.3 2 0 0 2 2 2 0 WCCH motif Auxin_resp PF06507.11 MSTRG.143054.1_2 - 0.13 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Auxin response factor PUF PF00806.17 MSTRG.97498.1_2 - 1.4e-30 103.1 5.8 1.2e-10 40.3 0.1 3.7 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat CPL PF08144.9 MSTRG.97498.1_2 - 0.026 14.7 0.0 2.1 8.5 0.0 2.1 1 1 1 2 2 2 0 CPL (NUC119) domain FYVE_2 PF02318.14 MSTRG.97498.1_2 - 0.03 14.4 1.2 0.042 13.9 1.2 1.3 1 1 0 1 1 1 0 FYVE-type zinc finger Ku_PK_bind PF08785.9 MSTRG.97498.1_2 - 0.047 13.7 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Ku C terminal domain like Leu_zip PF15294.4 MSTRG.141891.1_2 - 0.023 14.1 2.0 0.027 13.9 2.0 1.0 1 0 0 1 1 1 0 Leucine zipper Ribosomal_L5e PF17144.2 MSTRG.141891.1_3 - 0.58 10.0 3.3 0.8 9.5 3.3 1.3 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 DUF3884 PF13024.4 MSTRG.110150.1_2 - 0.06 12.8 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) DDE_Tnp_IS66_C PF13817.4 MSTRG.18606.1_2 - 0.095 12.8 0.0 7.2 6.8 0.0 2.2 2 0 0 2 2 2 0 IS66 C-terminal element Phage_Orf51 PF06194.9 MSTRG.18606.1_2 - 0.16 11.9 5.5 1.3 9.0 0.7 2.1 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 DUF1564 PF07600.9 MSTRG.18606.1_2 - 0.22 11.1 1.0 1.3 8.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DDE_Tnp_IS66_C PF13817.4 MSTRG.18606.1_3 - 0.028 14.5 0.0 4 7.6 0.0 2.1 2 0 0 2 2 2 0 IS66 C-terminal element YqzL PF14006.4 MSTRG.126850.1_1 - 0.11 12.8 0.2 0.16 12.2 0.2 1.2 1 0 0 1 1 1 0 YqzL-like protein Mob1_phocein PF03637.15 MSTRG.139991.1_1 - 1.4e-82 275.6 0.2 2.2e-82 274.9 0.2 1.3 1 0 0 1 1 1 1 Mob1/phocein family AMP-binding PF00501.26 MSTRG.131617.1_1 - 0.059 11.8 0.0 0.076 11.5 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme MHC_I PF00129.16 MSTRG.22162.2_2 - 1.6e-36 125.4 2.0 2.1e-36 125.0 2.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 MSTRG.22162.2_2 - 2.5e-14 53.4 0.1 7.6e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 MSTRG.22162.2_2 - 0.011 16.2 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.23 MSTRG.22162.2_2 - 0.017 15.1 0.0 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain MHC_II_alpha PF00993.18 MSTRG.22162.2_2 - 0.038 13.6 0.3 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain MHC_I_3 PF16497.3 MSTRG.22162.2_2 - 0.052 12.9 0.2 0.086 12.2 0.2 1.3 1 0 0 1 1 1 0 MHC-I family domain C2-set_2 PF08205.10 MSTRG.22162.2_2 - 0.082 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DAZAP2 PF11029.6 MSTRG.57537.1_3 - 0.027 15.3 0.0 0.04 14.7 0.0 1.2 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) PRIMA1 PF16101.3 MSTRG.57537.1_3 - 0.11 12.4 1.5 0.2 11.6 1.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1290 PF06947.10 MSTRG.90150.1_1 - 3.2e-05 23.8 2.7 3.4 7.7 0.0 5.1 2 2 3 5 5 5 2 Protein of unknown function (DUF1290) DUF1272 PF06906.9 MSTRG.90150.1_1 - 1.7 8.7 10.2 33 4.5 0.1 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1272) DUF1272 PF06906.9 MSTRG.90150.1_2 - 0.18 11.8 7.7 16 5.6 0.1 4.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1272) DUF1290 PF06947.10 MSTRG.90150.1_3 - 0.0039 17.1 0.8 16 5.5 0.0 3.8 2 1 2 4 4 4 1 Protein of unknown function (DUF1290) DUF1272 PF06906.9 MSTRG.90150.1_3 - 0.014 15.3 7.1 8.9 6.4 0.0 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1272) Gag_p19 PF02228.14 MSTRG.90150.1_3 - 0.16 12.3 0.7 4.3 7.7 0.1 2.7 1 1 3 4 4 4 0 Major core protein p19 DUF2374 PF09574.8 MSTRG.90150.1_3 - 3.6 7.3 23.0 5.3 6.8 0.7 5.5 1 1 5 6 6 6 0 Protein of unknown function (Duf2374) ecTbetaR2 PF08917.8 MSTRG.93725.1_1 - 2e-42 143.5 12.6 2.2e-42 143.3 12.6 1.0 1 0 0 1 1 1 1 Transforming growth factor beta receptor 2 ectodomain PH PF00169.27 MSTRG.44966.1_2 - 6.1e-13 49.1 0.3 7.9e-13 48.7 0.3 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 MSTRG.44966.1_2 - 0.00014 22.1 0.4 0.00018 21.8 0.4 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.4 MSTRG.44966.1_2 - 0.13 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 PH domain CNOT1_CAF1_bind PF16415.3 MSTRG.141700.1_2 - 5.1e-59 199.2 2.5 5.5e-59 199.1 2.5 1.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain RasGEF PF00617.17 MSTRG.64761.1_2 - 1.2e-36 126.3 0.5 1.3e-36 126.2 0.5 1.0 1 0 0 1 1 1 1 RasGEF domain DUF4787 PF16029.3 MSTRG.64761.1_2 - 0.03 14.2 0.3 0.076 13.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4787) Ribosomal_S18 PF01084.18 MSTRG.18030.1_1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S18 Ras PF00071.20 MSTRG.78979.2_1 - 6.6e-57 191.5 0.3 8.9e-57 191.1 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 MSTRG.78979.2_1 - 5.4e-20 71.7 0.0 8.5e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 MSTRG.78979.2_1 - 5.1e-08 32.4 0.1 7.4e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 MSTRG.78979.2_1 - 0.00012 21.5 0.2 0.00025 20.5 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 MSTRG.78979.2_1 - 0.0013 18.6 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 MSTRG.78979.2_1 - 0.0022 17.8 0.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 G-alpha PF00503.18 MSTRG.78979.2_1 - 0.04 12.9 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit DDE_3 PF13358.4 MSTRG.75461.1_3 - 1.8e-10 40.6 0.5 1.9e-10 40.5 0.5 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.24 MSTRG.75461.1_3 - 0.11 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain DUF3124 PF11322.6 MSTRG.102989.1_3 - 0.021 14.9 0.2 0.031 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) DZF PF07528.12 MSTRG.131535.1_1 - 3.3e-27 95.6 0.0 4.1e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 DZF domain Pkinase_Tyr PF07714.15 MSTRG.3109.1_2 - 2.1e-45 154.9 0.0 2.6e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 MSTRG.3109.1_2 - 7.4e-27 94.2 0.0 9.2e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.15 MSTRG.3109.1_2 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RVT_1 PF00078.25 MSTRG.37431.1_3 - 2.1e-05 24.0 0.1 2.6e-05 23.7 0.1 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ERK-JNK_inhib PF15002.4 MSTRG.136286.1_1 - 4.5e-24 85.1 0.0 4.8e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor TMEM213 PF15192.4 MSTRG.42340.1_3 - 0.0031 17.3 1.1 0.0039 17.0 1.1 1.2 1 0 0 1 1 1 1 TMEM213 family Qn_am_d_aIII PF09099.8 MSTRG.66143.1_2 - 0.047 14.0 0.0 0.049 13.9 0.0 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III DUF4371 PF14291.4 MSTRG.103958.1_3 - 0.0058 16.2 0.0 0.0078 15.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DnaJ PF00226.29 MSTRG.31560.1_3 - 1.2e-07 31.6 0.6 1.9e-07 31.0 0.1 1.6 2 0 0 2 2 2 1 DnaJ domain PHD_2 PF13831.4 MSTRG.39131.1_2 - 0.022 14.2 0.5 0.022 14.2 0.5 2.0 2 0 0 2 2 2 0 PHD-finger PHD PF00628.27 MSTRG.39131.1_2 - 1.4 8.7 6.4 1.6 8.6 0.6 2.2 2 0 0 2 2 2 0 PHD-finger HHH_5 PF14520.4 MSTRG.39131.1_3 - 0.0035 17.8 0.0 0.0057 17.1 0.0 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.13 MSTRG.39131.1_3 - 0.021 14.4 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain 7tm_1 PF00001.19 MSTRG.70638.1_2 - 0.075 12.1 0.7 0.077 12.1 0.7 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SSP160 PF06933.9 MSTRG.114607.1_3 - 6.8 4.6 12.6 7.4 4.5 12.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SH2 PF00017.22 MSTRG.55840.1_2 - 1.9e-12 46.9 0.1 2.8e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 SH2 domain Selenoprotein_S PF06936.9 MSTRG.52032.1_2 - 0.00063 19.5 4.7 0.00063 19.5 4.7 2.1 2 0 0 2 2 2 1 Selenoprotein S (SelS) Strep_SA_rep PF06696.9 MSTRG.52032.1_2 - 0.18 11.6 2.5 0.43 10.4 2.5 1.6 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DUF4118 PF13493.4 MSTRG.69091.1_1 - 0.046 13.4 2.6 1 9.0 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4118) LRR_2 PF07723.11 MSTRG.69091.1_1 - 2 9.1 9.4 15 6.4 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat G-alpha PF00503.18 MSTRG.61551.1_1 - 1.9e-121 405.4 2.4 2.3e-121 405.1 2.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 MSTRG.61551.1_1 - 1.4e-16 60.3 0.1 2.6e-12 46.4 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 MSTRG.61551.1_1 - 0.00023 20.4 2.4 0.023 13.9 0.8 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.11 MSTRG.61551.1_1 - 0.00044 20.4 0.3 0.78 9.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.4 MSTRG.61551.1_1 - 0.062 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF4644 PF15486.4 MSTRG.38180.1_2 - 0.061 12.9 0.0 0.072 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) Sema PF01403.17 MSTRG.38746.1_1 - 1.2e-40 139.4 0.3 1.5e-40 139.2 0.3 1.0 1 0 0 1 1 1 1 Sema domain PH PF00169.27 MSTRG.37649.1_2 - 7.2e-05 23.1 0.0 9.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 PH domain C_tripleX PF02363.17 MSTRG.114074.1_1 - 0.004 17.2 28.6 1.3 9.4 0.9 4.9 2 1 3 5 5 5 4 Cysteine rich repeat PSI_8 PF00796.16 MSTRG.114074.1_2 - 1.5 8.6 8.4 11 5.8 0.5 3.1 2 1 0 2 2 2 0 Photosystem I reaction centre subunit VIII zf-C2H2 PF00096.24 MSTRG.114734.1_3 - 8.5e-06 25.8 2.3 1.4e-05 25.2 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 MSTRG.114734.1_3 - 0.00042 20.4 1.0 0.00061 19.9 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.4 MSTRG.114734.1_3 - 0.00076 20.0 1.5 0.0011 19.4 1.5 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.4 MSTRG.114734.1_3 - 0.008 16.5 2.8 0.4 11.1 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.4 MSTRG.114734.1_3 - 0.013 15.3 0.4 0.018 14.8 0.4 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger UDP-g_GGTase PF06427.9 MSTRG.5335.1_2 - 1.3e-14 53.2 0.1 1.4e-14 53.1 0.1 1.0 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Elongin_A PF06881.9 MSTRG.48212.1_2 - 3.6e-28 98.0 1.0 4.4e-28 97.7 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A HTH_Tnp_Tc3_2 PF01498.16 MSTRG.32777.1_3 - 2.5e-09 37.1 0.2 4.1e-09 36.4 0.2 1.3 1 0 0 1 1 1 1 Transposase P2X_receptor PF00864.17 MSTRG.29058.1_1 - 0.00055 19.0 0.0 0.00088 18.3 0.0 1.3 1 0 0 1 1 1 1 ATP P2X receptor SRI PF08236.9 MSTRG.29058.1_2 - 0.036 14.1 1.9 0.045 13.8 1.9 1.1 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Tweety PF04906.11 MSTRG.5917.1_1 - 0.00035 19.2 0.3 0.00042 19.0 0.3 1.0 1 0 0 1 1 1 1 Tweety IncA PF04156.12 MSTRG.5917.1_1 - 0.0024 17.6 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 IncA protein Herpes_gE PF02480.14 MSTRG.5917.1_1 - 0.0034 16.1 0.0 0.0035 16.0 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF3329 PF11808.6 MSTRG.5917.1_1 - 0.018 15.3 0.0 0.024 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) WBP-1 PF11669.6 MSTRG.5917.1_1 - 0.019 15.5 0.0 0.021 15.3 0.0 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 FAM163 PF15069.4 MSTRG.5917.1_1 - 0.026 14.8 0.0 0.027 14.8 0.0 1.1 1 0 0 1 1 1 0 FAM163 family EphA2_TM PF14575.4 MSTRG.5917.1_1 - 0.03 15.0 0.0 0.033 14.9 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PDGLE PF13190.4 MSTRG.5917.1_1 - 0.034 13.9 0.4 0.054 13.3 0.4 1.3 1 0 0 1 1 1 0 PDGLE domain SIT PF15330.4 MSTRG.5917.1_1 - 0.035 14.4 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Orthoreo_P10 PF07204.9 MSTRG.5917.1_1 - 0.051 13.4 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF2207 PF09972.7 MSTRG.5917.1_1 - 0.052 12.2 0.0 0.061 12.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.4 MSTRG.5917.1_1 - 0.052 13.3 0.0 0.061 13.1 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family ETRAMP PF09716.8 MSTRG.5917.1_1 - 0.06 13.3 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Syndecan PF01034.18 MSTRG.5917.1_1 - 0.087 12.6 0.3 0.13 12.1 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain CD34_antigen PF06365.10 MSTRG.5917.1_1 - 0.091 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF1191 PF06697.10 MSTRG.5917.1_1 - 0.091 11.8 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) LYRIC PF15686.3 MSTRG.5917.1_1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Adeno_E3_CR2 PF02439.13 MSTRG.5917.1_1 - 6 6.6 7.0 15 5.3 7.0 1.6 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 Folliculin_C PF16692.3 MSTRG.109688.1_2 - 0.0037 16.8 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Folliculin C-terminal domain GOLD_2 PF13897.4 MSTRG.60231.1_1 - 1.7e-62 209.9 0.7 2.7e-62 209.2 0.7 1.3 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking Acyltransferase PF01553.19 MSTRG.44191.1_1 - 0.00097 18.6 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.3 MSTRG.44191.1_1 - 0.081 12.9 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Acyltransferase C-terminus fn3 PF00041.19 MSTRG.85954.1_3 - 3.2e-15 56.1 0.4 1.4e-13 50.8 0.3 2.5 2 0 0 2 2 2 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.3 MSTRG.85954.1_3 - 0.025 15.0 1.8 0.05 14.0 0.2 2.3 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Ank_2 PF12796.5 MSTRG.34440.1_2 - 7.2e-06 26.4 0.1 7.8e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 MSTRG.34440.1_2 - 0.002 18.5 0.2 4.1 8.0 0.1 2.0 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.4 MSTRG.34440.1_2 - 0.0025 18.0 0.2 2.4 8.5 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 MSTRG.34440.1_2 - 0.0052 17.1 0.1 0.19 12.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat zf-CDGSH PF09360.8 MSTRG.100601.1_3 - 0.0045 17.0 0.1 0.0082 16.2 0.1 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type DDE_3 PF13358.4 MSTRG.57210.1_2 - 0.00027 20.6 0.0 0.00032 20.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PRP38_assoc PF12871.5 MSTRG.36355.1_2 - 0.013 15.9 4.5 0.016 15.6 4.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term FAM176 PF14851.4 MSTRG.36355.1_2 - 0.36 10.4 3.7 0.37 10.3 3.7 1.1 1 0 0 1 1 1 0 FAM176 family Sigma70_r4_2 PF08281.10 MSTRG.103813.1_2 - 0.0018 17.7 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.4 MSTRG.103813.1_2 - 0.097 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain RE_XcyI PF09571.8 MSTRG.101331.1_3 - 0.048 12.8 0.0 0.054 12.6 0.0 1.0 1 0 0 1 1 1 0 XcyI restriction endonuclease EF1_GNE PF00736.17 MSTRG.116090.1_2 - 9.4e-38 128.1 0.3 1.7e-37 127.3 0.3 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.7 MSTRG.116090.1_2 - 5e-14 52.3 7.7 5e-14 52.3 7.7 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_6 PF17171.2 MSTRG.116090.1_2 - 0.0093 15.6 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YL1 PF05764.11 MSTRG.116090.1_2 - 0.047 13.7 1.7 0.061 13.3 1.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein ERM PF00769.17 MSTRG.75257.1_3 - 0.0017 18.1 21.2 0.0026 17.5 21.2 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family CALCOCO1 PF07888.9 MSTRG.75257.1_3 - 0.011 14.2 26.2 0.015 13.8 26.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlxA PF14282.4 MSTRG.75257.1_3 - 0.089 12.7 16.2 0.075 12.9 12.5 2.6 1 1 1 2 2 2 0 FlxA-like protein DUF2009 PF09418.8 MSTRG.75257.1_3 - 0.16 10.9 8.4 0.25 10.2 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) APG6 PF04111.10 MSTRG.75257.1_3 - 0.25 10.5 21.3 0.42 9.8 21.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.4 MSTRG.75257.1_3 - 0.44 9.7 11.4 0.68 9.1 11.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.12 MSTRG.75257.1_3 - 0.73 9.5 25.3 0.38 10.4 11.1 1.8 1 1 1 2 2 2 0 IncA protein ADIP PF11559.6 MSTRG.75257.1_3 - 0.76 9.7 24.6 2.5 8.0 20.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1744 PF08490.10 MSTRG.75257.1_3 - 0.86 8.0 4.4 1.3 7.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Jnk-SapK_ap_N PF09744.7 MSTRG.75257.1_3 - 1.1 9.4 26.1 0.2 11.7 20.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Caudo_TAP PF02413.15 MSTRG.75257.1_3 - 1.1 9.3 7.3 2.8 8.1 7.2 1.7 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Reo_sigmaC PF04582.10 MSTRG.75257.1_3 - 1.4 8.1 7.5 2.6 7.2 1.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Phage_GPO PF05929.9 MSTRG.75257.1_3 - 2.2 7.7 12.2 3.4 7.1 12.2 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CREPT PF16566.3 MSTRG.75257.1_3 - 3 7.9 14.4 4.9 7.2 13.8 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.10 MSTRG.75257.1_3 - 5.2 7.6 18.8 1.2 9.7 2.3 3.8 1 1 3 4 4 4 0 SlyX DUF724 PF05266.12 MSTRG.75257.1_3 - 6 6.5 21.3 11 5.6 19.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.17 MSTRG.75257.1_3 - 7 4.3 13.0 9.2 3.9 13.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Y_phosphatase PF00102.25 MSTRG.93352.1_2 - 7.4e-75 251.4 0.5 1.3e-46 158.9 0.1 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.18 MSTRG.93352.1_2 - 0.00038 20.1 0.0 0.00075 19.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.4 MSTRG.93352.1_2 - 0.00083 19.4 0.3 0.0034 17.4 0.1 2.1 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.4 MSTRG.93352.1_2 - 0.0034 17.2 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Hormone_recep PF00104.28 MSTRG.136818.1_3 - 1.8e-17 63.5 0.0 3.2e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor N-glycanase_C PF09113.8 MSTRG.66149.1_3 - 1.2e-07 31.4 0.1 1.4e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Peptide-N-glycosidase F, C terminal Carb_anhydrase PF00194.19 MSTRG.2340.1_1 - 7.9e-79 264.7 0.2 9.4e-79 264.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase UL11 PF11094.6 MSTRG.57732.1_1 - 0.096 12.4 0.7 0.14 11.9 0.7 1.2 1 0 0 1 1 1 0 Membrane-associated tegument protein L27_1 PF09058.8 MSTRG.92287.1_1 - 0.0069 16.3 0.1 0.01 15.7 0.1 1.2 1 0 0 1 1 1 1 L27_1 HTH_23 PF13384.4 MSTRG.94311.1_1 - 4.6e-06 26.1 0.0 7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.10 MSTRG.94311.1_1 - 0.01 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.14 MSTRG.94311.1_1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.4 MSTRG.94311.1_1 - 0.088 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.23 MSTRG.45556.1_1 - 6.3e-09 35.4 0.0 8.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RabGAP-TBC PF00566.16 MSTRG.97326.1_3 - 0.27 10.7 4.1 0.32 10.5 4.1 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain HTH_Tnp_Tc3_2 PF01498.16 MSTRG.58802.1_2 - 5.9e-08 32.7 0.4 1.2e-07 31.7 0.4 1.5 1 0 0 1 1 1 1 Transposase DUF4744 PF15918.3 MSTRG.58802.1_3 - 0.12 13.1 0.7 0.2 12.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) DNA_pol_B_palm PF14792.4 MSTRG.23474.1_2 - 1.5e-32 112.0 0.0 1.7e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase beta palm NTP_transf_2 PF01909.21 MSTRG.23474.1_2 - 0.0088 16.2 0.1 0.013 15.6 0.1 1.3 1 1 0 1 1 1 1 Nucleotidyltransferase domain Nup35_RRM_2 PF14605.4 MSTRG.23474.1_2 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1891 PF09004.8 MSTRG.97513.1_1 - 1.1e-05 24.8 0.5 1.1e-05 24.8 0.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1891) MMR_HSR1 PF01926.21 MSTRG.91899.2_3 - 0.00051 20.0 0.0 0.00096 19.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.4 MSTRG.91899.2_3 - 0.002 17.7 0.0 0.0044 16.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.4 MSTRG.91899.2_3 - 0.0041 17.4 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain IIGP PF05049.11 MSTRG.91899.2_3 - 0.014 14.3 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.15 MSTRG.91899.2_3 - 0.11 12.1 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.20 MSTRG.91899.2_3 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase bZIP_1 PF00170.19 MSTRG.86249.1_2 - 1.5e-14 53.7 4.7 2.7e-14 52.9 4.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 MSTRG.86249.1_2 - 3e-08 33.5 6.4 5.1e-08 32.7 6.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.11 MSTRG.86249.1_2 - 0.00034 19.8 1.9 0.0004 19.6 1.9 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region CCDC23 PF15674.3 MSTRG.86249.1_2 - 0.0054 16.6 1.3 0.013 15.3 1.3 1.7 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 RasGAP_C PF03836.13 MSTRG.86249.1_2 - 0.025 14.6 4.0 0.035 14.1 4.0 1.3 1 0 0 1 1 1 0 RasGAP C-terminus DUF4239 PF14023.4 MSTRG.86249.1_2 - 0.74 9.4 2.0 1 8.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Pox_G5 PF04599.10 MSTRG.86249.1_2 - 4.1 6.2 5.3 4.9 5.9 5.3 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein CC2-LZ PF16516.3 MSTRG.51662.2_3 - 1e-09 38.5 16.4 1e-09 38.5 16.4 4.1 1 1 1 3 3 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4407 PF14362.4 MSTRG.51662.2_3 - 0.0041 16.4 29.0 0.1 11.8 15.6 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) IncA PF04156.12 MSTRG.51662.2_3 - 0.036 13.7 52.0 0.022 14.4 24.0 2.2 2 0 0 2 2 2 0 IncA protein HALZ PF02183.16 MSTRG.51662.2_3 - 0.06 13.4 14.6 0.21 11.7 0.6 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper CALCOCO1 PF07888.9 MSTRG.51662.2_3 - 0.36 9.2 38.5 0.03 12.8 14.7 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.19 MSTRG.51662.2_3 - 0.53 9.7 42.4 0.71 9.3 10.6 3.1 2 1 1 3 3 3 0 Intermediate filament protein APG6 PF04111.10 MSTRG.51662.2_3 - 0.85 8.8 41.9 0.52 9.5 19.8 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.7 MSTRG.51662.2_3 - 1.5 8.7 47.4 0.62 10.0 17.3 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.10 MSTRG.51662.2_3 - 1.7 8.5 7.9 9 6.2 0.4 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.4 MSTRG.51662.2_3 - 2.5 7.6 46.1 0.061 12.8 16.3 3.6 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.10 MSTRG.51662.2_3 - 5.7 7.4 13.5 21 5.5 0.8 3.8 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LPP PF04728.11 MSTRG.51662.2_3 - 6.1 7.2 13.3 3.5 8.0 1.2 4.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Prefoldin PF02996.15 MSTRG.51662.2_3 - 9.4 6.1 30.3 1.1 9.0 2.9 4.6 2 1 2 4 4 4 0 Prefoldin subunit LRRNT PF01462.16 MSTRG.59512.1_2 - 0.21 11.2 0.0 0.21 11.2 0.0 1.9 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain PI3_PI4_kinase PF00454.25 MSTRG.107770.1_3 - 1.1e-44 153.0 0.1 2.6e-43 148.5 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.4 MSTRG.107770.1_3 - 0.0019 17.5 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) LTD PF00932.17 MSTRG.22632.1_2 - 4.6e-16 59.0 0.1 5.8e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 Lamin Tail Domain Calsequestrin PF01216.15 MSTRG.22220.1_3 - 1.9e-65 221.2 13.1 2.4e-65 220.9 13.1 1.0 1 0 0 1 1 1 1 Calsequestrin ZapB PF06005.10 MSTRG.45816.1_3 - 0.0033 17.7 9.3 0.0033 17.7 9.3 1.9 2 0 0 2 2 2 1 Cell division protein ZapB UPF0449 PF15136.4 MSTRG.45816.1_3 - 0.0049 17.2 6.2 0.0049 17.2 6.2 1.5 1 1 1 2 2 2 1 Uncharacterised protein family UPF0449 DivIC PF04977.13 MSTRG.45816.1_3 - 0.0098 15.5 7.7 0.0098 15.5 7.7 2.0 1 1 1 2 2 2 1 Septum formation initiator DUF3450 PF11932.6 MSTRG.45816.1_3 - 0.028 13.6 10.0 0.03 13.5 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.4 MSTRG.45816.1_3 - 0.029 13.6 12.2 0.032 13.5 12.2 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FliD_C PF07195.10 MSTRG.45816.1_3 - 0.03 13.6 5.2 0.31 10.3 5.2 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TPR_MLP1_2 PF07926.10 MSTRG.45816.1_3 - 0.058 13.3 12.8 0.086 12.8 12.8 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.11 MSTRG.45816.1_3 - 0.068 13.7 5.9 0.093 13.2 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Nup88 PF10168.7 MSTRG.45816.1_3 - 0.16 9.6 12.5 0.16 9.6 12.5 1.0 1 0 0 1 1 1 0 Nuclear pore component GED PF02212.16 MSTRG.45816.1_3 - 0.34 11.0 5.1 0.54 10.3 4.8 1.6 1 1 0 1 1 1 0 Dynamin GTPase effector domain MctB PF11382.6 MSTRG.45816.1_3 - 0.38 10.3 2.6 0.36 10.4 2.0 1.3 1 1 0 1 1 1 0 Copper transport outer membrane protein, MctB Phage_GPO PF05929.9 MSTRG.45816.1_3 - 0.56 9.7 5.2 0.6 9.6 5.2 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6 PF04111.10 MSTRG.45816.1_3 - 0.7 9.1 12.3 0.7 9.1 12.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TSC22 PF01166.16 MSTRG.45816.1_3 - 1.4 9.1 9.2 1 9.6 4.4 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family FlaC_arch PF05377.9 MSTRG.45816.1_3 - 1.9 8.8 8.5 0.15 12.3 3.1 2.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NYD-SP28_assoc PF14775.4 MSTRG.45816.1_3 - 2.3 8.2 9.8 1.1 9.3 5.0 2.7 1 1 1 2 2 2 0 Sperm tail C-terminal domain TMPIT PF07851.11 MSTRG.45816.1_3 - 2.5 7.1 6.4 2.8 7.0 6.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.7 MSTRG.45816.1_3 - 3 6.7 11.3 2.9 6.7 11.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bap31 PF05529.10 MSTRG.45816.1_3 - 4.1 6.8 9.1 4.5 6.7 9.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4337 PF14235.4 MSTRG.45816.1_3 - 4.1 7.3 6.8 4.4 7.3 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) IncA PF04156.12 MSTRG.45816.1_3 - 7.1 6.2 13.0 9.2 5.9 13.0 1.3 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.13 MSTRG.45816.1_3 - 8.7 5.7 8.9 9 5.6 8.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM101 PF15068.4 MSTRG.96522.1_2 - 1.7e-14 54.2 0.4 2.5e-14 53.6 0.4 1.2 1 0 0 1 1 1 1 FAM101 family ERAP1_C PF11838.6 MSTRG.124137.1_3 - 4.9e-29 101.7 0.3 5.3e-29 101.6 0.3 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain fn3 PF00041.19 MSTRG.50860.1_2 - 1.1e-45 153.8 0.1 2.2e-14 53.4 0.0 3.4 3 0 0 3 3 3 3 Fibronectin type III domain I-set PF07679.14 MSTRG.50860.1_2 - 6.5e-23 80.5 0.0 6.2e-16 58.1 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.4 MSTRG.50860.1_2 - 2.8e-12 46.9 0.0 2.9e-06 27.7 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.3 MSTRG.50860.1_2 - 1.3e-07 31.9 0.0 0.083 13.3 0.0 4.3 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.4 MSTRG.50860.1_2 - 2.1e-05 24.6 0.0 0.016 15.4 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 MSTRG.50860.1_2 - 3.1e-05 23.8 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain SusE PF14292.4 MSTRG.50860.1_2 - 0.0013 19.0 0.0 6.3 7.1 0.0 3.4 3 1 0 3 3 3 1 SusE outer membrane protein Y_Y_Y PF07495.11 MSTRG.50860.1_2 - 0.0013 18.5 0.1 7.1 6.5 0.0 3.7 3 0 0 3 3 3 1 Y_Y_Y domain ig PF00047.23 MSTRG.50860.1_2 - 0.0062 16.5 0.0 4.8 7.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Tissue_fac PF01108.15 MSTRG.50860.1_2 - 0.025 14.2 0.1 0.9 9.3 0.0 2.9 3 1 0 3 3 3 0 Tissue factor DUF2716 PF10898.6 MSTRG.50860.1_2 - 0.11 12.7 0.0 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) Fer2_4 PF13510.4 MSTRG.116089.1_3 - 3.9e-19 68.3 0.2 6.9e-19 67.5 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.7 MSTRG.116089.1_3 - 1.3e-17 62.9 0.1 1.3e-17 62.9 0.1 2.3 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.25 MSTRG.116089.1_3 - 2e-10 40.4 3.6 3.3e-10 39.7 0.6 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Ank_2 PF12796.5 MSTRG.110560.1_1 - 3.1e-74 245.5 0.2 3.4e-16 59.5 0.0 6.1 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.4 MSTRG.110560.1_1 - 2.4e-66 218.5 3.4 3.7e-11 42.9 0.0 10.4 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank_4 PF13637.4 MSTRG.110560.1_1 - 9.1e-66 217.3 0.0 5e-09 36.4 0.0 8.9 3 1 8 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.28 MSTRG.110560.1_1 - 1.3e-61 202.4 0.0 1.5e-07 31.4 0.0 11.1 11 0 0 11 11 11 11 Ankyrin repeat Ank_3 PF13606.4 MSTRG.110560.1_1 - 3.5e-56 180.4 0.2 3.8e-06 26.7 0.0 11.1 11 0 0 11 11 11 11 Ankyrin repeat UDPG_MGDP_dh_C PF03720.13 MSTRG.110560.1_1 - 0.00031 21.0 0.3 13 6.2 0.0 4.4 4 1 0 4 4 4 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF3107 PF11305.6 MSTRG.110560.1_1 - 0.12 12.5 0.2 7.1 6.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3107) DUF4754 PF15946.3 MSTRG.110560.1_1 - 0.19 11.9 0.3 20 5.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4754) MoaE PF02391.15 MSTRG.39737.1_2 - 3.7e-29 101.1 0.0 4.5e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 MoaE protein V-set PF07686.15 MSTRG.21329.1_2 - 0.087 12.9 0.1 0.087 12.9 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain DUF3449 PF11931.6 MSTRG.130855.1_1 - 0.037 13.7 0.3 0.043 13.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.140233.1_3 - 2.3e-13 50.1 1.5 2.7e-13 49.8 1.5 1.1 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.4 MSTRG.140233.1_3 - 0.045 13.3 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Arg_repressor PF01316.19 MSTRG.140233.1_3 - 0.067 12.8 0.1 0.083 12.5 0.1 1.2 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain CobT PF06213.10 MSTRG.143502.1_1 - 0.037 13.3 12.3 0.044 13.0 12.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Spore_coat_CotO PF14153.4 MSTRG.143502.1_1 - 0.11 12.3 12.7 0.14 12.0 12.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DNA_pol_phi PF04931.11 MSTRG.143502.1_1 - 0.52 8.2 7.0 0.62 8.0 7.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2360 PF10152.7 MSTRG.143502.1_1 - 0.8 10.0 14.6 1.1 9.5 14.6 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Pannexin_like PF12534.6 MSTRG.143502.1_1 - 1.3 7.9 4.2 1.6 7.6 4.2 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Striatin PF08232.10 MSTRG.143502.1_1 - 1.4 9.3 9.0 2.1 8.8 9.0 1.2 1 0 0 1 1 1 0 Striatin family CDC45 PF02724.12 MSTRG.143502.1_1 - 1.9 6.6 7.8 2.3 6.3 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.7 MSTRG.143502.1_1 - 2 8.4 11.2 2.4 8.1 11.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CENP-U PF13097.4 MSTRG.143502.1_1 - 2.7 7.8 9.4 3.9 7.3 9.4 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF1387 PF07139.9 MSTRG.143502.1_1 - 4.3 6.8 9.7 4.3 6.8 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Herpes_DNAp_acc PF04929.10 MSTRG.143502.1_1 - 4.5 6.0 11.6 5.1 5.8 11.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor UPF0544 PF15749.3 MSTRG.143502.1_1 - 5.4 7.6 6.4 15 6.2 6.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0544 RR_TM4-6 PF06459.10 MSTRG.143502.1_1 - 8.7 5.9 11.6 9.5 5.8 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 5_nucleotid PF05761.12 MSTRG.143888.1_1 - 4.6e-45 154.2 0.1 6.4e-45 153.7 0.1 1.1 1 0 0 1 1 1 1 5' nucleotidase family 5_nucleotid PF05761.12 MSTRG.143888.1_2 - 1.2e-62 212.2 0.9 8.3e-38 130.3 0.3 2.1 2 0 0 2 2 2 2 5' nucleotidase family DUF1563 PF07599.9 MSTRG.143888.1_2 - 0.087 12.8 1.5 7.5 6.6 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) HTH_Tnp_Tc3_2 PF01498.16 MSTRG.143125.1_2 - 2.8e-22 78.6 0.5 2.8e-22 78.6 0.5 1.8 2 1 0 2 2 2 1 Transposase HTH_38 PF13936.4 MSTRG.143125.1_2 - 5.4e-05 22.8 0.9 0.00024 20.7 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.4 MSTRG.143125.1_2 - 0.00029 20.4 0.1 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.4 MSTRG.143125.1_2 - 0.0031 18.0 0.1 0.0091 16.5 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.16 MSTRG.143125.1_2 - 0.045 13.5 0.2 0.066 13.0 0.2 1.3 1 0 0 1 1 1 0 'Paired box' domain Arg_repressor PF01316.19 MSTRG.143125.1_2 - 0.076 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Ribosomal_S13_N PF08069.10 MSTRG.143125.1_2 - 0.099 12.6 0.2 1 9.3 0.1 2.4 1 1 1 2 2 2 0 Ribosomal S13/S15 N-terminal domain HTH_28 PF13518.4 MSTRG.143125.1_2 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Lysyl_oxidase PF01186.15 MSTRG.40921.1_2 - 2.3e-40 138.3 0.4 2.5e-40 138.2 0.4 1.0 1 0 0 1 1 1 1 Lysyl oxidase Cadherin_C PF01049.15 MSTRG.106701.1_3 - 3.1e-10 40.3 2.0 4.7e-10 39.8 2.0 1.2 1 0 0 1 1 1 1 Cadherin cytoplasmic region EphA2_TM PF14575.4 MSTRG.106701.1_3 - 0.0024 18.5 0.0 0.0037 17.9 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2304 PF10066.7 MSTRG.106701.1_3 - 0.0024 17.9 0.4 0.0031 17.6 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2304) Rifin_STEVOR PF02009.14 MSTRG.106701.1_3 - 0.0031 17.3 0.2 0.0035 17.2 0.2 1.1 1 0 0 1 1 1 1 Rifin/stevor family CD34_antigen PF06365.10 MSTRG.106701.1_3 - 0.0064 16.0 0.0 0.0068 15.9 0.0 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF4381 PF14316.4 MSTRG.106701.1_3 - 0.0087 16.2 0.2 0.011 15.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) TMEM154 PF15102.4 MSTRG.106701.1_3 - 0.0094 15.7 0.3 0.0099 15.7 0.3 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF2207 PF09972.7 MSTRG.106701.1_3 - 0.019 13.6 0.0 0.022 13.4 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF912 PF06024.10 MSTRG.106701.1_3 - 0.03 14.5 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) IncA PF04156.12 MSTRG.106701.1_3 - 0.034 13.8 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 IncA protein SIT PF15330.4 MSTRG.106701.1_3 - 0.039 14.2 0.1 0.052 13.8 0.1 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Amnionless PF14828.4 MSTRG.106701.1_3 - 0.046 12.4 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF3377 PF11857.6 MSTRG.106701.1_3 - 0.048 13.4 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) FixQ PF05545.9 MSTRG.106701.1_3 - 0.058 13.2 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ YajC PF02699.13 MSTRG.106701.1_3 - 0.069 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Syndecan PF01034.18 MSTRG.106701.1_3 - 0.075 12.8 1.0 0.13 12.1 1.0 1.4 1 0 0 1 1 1 0 Syndecan domain CBP_BcsF PF11120.6 MSTRG.106701.1_3 - 0.081 12.8 2.4 0.12 12.3 2.4 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF DUF2254 PF10011.7 MSTRG.106701.1_3 - 0.12 11.1 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF4448 PF14610.4 MSTRG.106701.1_3 - 0.15 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ASFV_J13L PF05568.9 MSTRG.106701.1_3 - 0.15 11.6 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Baculo_11_kDa PF06143.9 MSTRG.106701.1_3 - 0.17 11.4 2.2 0.26 10.7 2.2 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Herpes_gE PF02480.14 MSTRG.106701.1_3 - 0.18 10.4 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Dehydrin PF00257.17 MSTRG.65211.1_2 - 0.12 12.8 3.4 0.15 12.5 3.4 1.3 1 0 0 1 1 1 0 Dehydrin CBM_5_12 PF02839.12 MSTRG.65211.1_3 - 0.17 11.7 0.4 0.17 11.7 0.4 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain PA_decarbox PF05870.9 MSTRG.44519.1_2 - 0.0009 18.8 8.3 4.7 6.7 0.0 6.2 2 1 5 7 7 7 4 Phenolic acid decarboxylase (PAD) F_bP_aldolase PF01116.18 MSTRG.44519.1_3 - 4 6.7 6.9 7 5.9 2.2 2.5 1 1 1 2 2 2 0 Fructose-bisphosphate aldolase class-II DDE_3 PF13358.4 MSTRG.79841.1_1 - 0.01 15.4 0.1 0.012 15.2 0.1 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease Guanylate_kin PF00625.19 MSTRG.120506.1_3 - 8.1e-09 35.3 0.0 2.5e-08 33.7 0.0 1.7 1 1 1 2 2 2 1 Guanylate kinase SH3_2 PF07653.15 MSTRG.120506.1_3 - 4e-05 23.1 0.0 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PrsW-protease PF13367.4 MSTRG.111862.1_2 - 0.026 13.9 0.1 0.029 13.7 0.1 1.0 1 0 0 1 1 1 0 Protease prsW family Exo_endo_phos_2 PF14529.4 MSTRG.75129.1_3 - 0.022 14.5 0.1 0.069 12.9 0.1 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase BBS2_Mid PF14783.4 MSTRG.60655.1_3 - 0.045 13.7 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region ATP-grasp_2 PF08442.8 MSTRG.3874.1_3 - 2.2e-28 99.1 0.1 2.6e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.4 MSTRG.3874.1_3 - 0.00014 21.3 0.0 0.00015 21.1 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.17 MSTRG.3874.1_3 - 0.00045 19.9 0.0 0.00057 19.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RVT_1 PF00078.25 MSTRG.55318.1_2 - 0.0096 15.3 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.25 MSTRG.55318.1_3 - 4.1e-10 39.4 0.0 6.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ART PF01129.16 MSTRG.77627.1_1 - 1.2e-37 129.2 0.3 1.8e-37 128.6 0.3 1.2 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase NTF2 PF02136.18 MSTRG.100658.1_1 - 2e-30 105.7 0.0 2.7e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain # # Program: hmmscan # Version: 3.1b2 (February 2015) # Pipeline mode: SCAN # Query file: /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/realdata/rainbow/wd/merged_no_G.p.fa # Target file: /home/yduan/database/Pfam/Pfam-A.hmm # Option settings: hmmscan -o /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/realdata/rainbow/hmmscan.outm --tblout /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/realdata/rainbow/hmmscan.t.out /home/yduan/database/Pfam/Pfam-A.hmm /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/realdata/rainbow/wd/merged_no_G.p.fa # Current dir: /home/yduan/work_file/lncRNAdb/methods_assement # Date: Tue Aug 21 15:04:41 2018 # [ok]