# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- NUC205 PF08168.9 ENSRNA049472983-T1_01001134_1 - 0.36 10.3 2.0 2.4 7.6 2.4 1.9 2 0 0 2 2 2 0 NUC205 domain RuBisCO_large PF00016.18 ENSRNA049471270-T1_01002130_1 - 9.7e-05 21.6 0.1 0.00012 21.3 0.1 1.1 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain zinc_ribbon_4 PF13717.4 ENSRNA049459213-T1_01603130_1 - 0.7 9.7 5.0 6.1 6.7 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Phage_P2_GpU PF06995.9 ENSRNA049455680-T1_01601140_3 - 0.012 15.1 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Phage P2 GpU SH3_9 PF14604.4 ENSRNA049450444-T1_03603130_2 - 0.17 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain ATHILA PF03078.13 ENSRNA049448859-T1_03601126_3 - 2.4e-17 62.8 0.6 2.7e-17 62.6 0.6 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family ATHILA PF03078.13 ENSRNA049448671-T1_03601126_3 - 9.6e-19 67.4 1.2 1.1e-18 67.2 1.2 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family ATHILA PF03078.13 ENSRNA049448509-T1_03601126_3 - 1.8e-23 83.0 0.9 1.9e-23 82.9 0.9 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family DUF4303 PF14136.4 ENSRNA049448509-T1_03601126_3 - 0.033 13.9 0.1 0.036 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) DUF2688 PF10892.6 ENSRNA049448458-T1_03601126_1 - 0.089 12.4 1.2 0.13 11.8 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2688) ATHILA PF03078.13 ENSRNA049448458-T1_03601126_3 - 1.5e-18 66.8 1.2 1.6e-18 66.6 1.2 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family ATHILA PF03078.13 ENSRNA049447420-T1_03601126_3 - 3.8e-23 81.9 1.1 4e-23 81.8 1.1 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family DUF4303 PF14136.4 ENSRNA049447420-T1_03601126_3 - 0.032 14.0 0.1 0.035 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) ATHILA PF03078.13 ENSRNA049447414-T1_03601126_3 - 2.5e-24 85.8 2.2 2.6e-24 85.7 2.2 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family ATHILA PF03078.13 ENSRNA049446305-T1_03601126_3 - 1.9e-23 82.9 2.4 2e-23 82.8 2.4 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family DUF4618 PF15397.4 ENSRNA049446305-T1_03601126_3 - 0.011 15.0 0.1 0.011 15.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4455 PF14643.4 ENSRNA049446305-T1_03601126_3 - 0.027 13.1 0.2 0.027 13.1 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) STAT_alpha PF01017.18 ENSRNA049446305-T1_03601126_3 - 0.027 14.2 0.1 0.033 13.9 0.1 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain NEP PF10167.7 ENSRNA049446305-T1_03601126_3 - 0.04 13.7 0.1 0.05 13.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein ATHILA PF03078.13 ENSRNA049449862-T1_03601126_3 - 2e-15 56.4 0.5 2e-15 56.4 0.5 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family ATHILA PF03078.13 ENSRNA049449869-T1_03601126_3 - 2.4e-18 66.1 0.9 2.6e-18 66.0 0.9 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family PDT PF00800.16 ENSRNA049449928-T1_03601126_2 - 0.041 13.6 0.0 0.044 13.4 0.0 1.0 1 0 0 1 1 1 0 Prephenate dehydratase ATHILA PF03078.13 ENSRNA049449928-T1_03601126_3 - 4.2e-15 55.4 1.2 4.8e-15 55.2 1.2 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family ATHILA PF03078.13 ENSRNA049452157-T1_03601126_3 - 2.1e-23 82.8 1.1 2.2e-23 82.7 1.1 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family SdpI PF13630.4 AT5G01965.1_03701101_1 - 0.024 14.6 0.9 0.052 13.5 0.9 1.7 1 1 0 1 1 1 0 SdpI/YhfL protein family Shugoshin_C PF07557.9 ENSRNA049474026-T1_06604130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049474488-T1_06604130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049475539-T1_06604130_2 - 3.7 7.3 5.6 0.48 10.1 0.1 2.3 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049475784-T1_06604130_2 - 1.7 8.4 8.4 0.48 10.1 0.1 2.4 2 0 0 2 2 2 0 Shugoshin C terminus SH3_9 PF14604.4 ENSRNA049454673-T1_07002130_1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Variant SH3 domain Pax2_C PF12403.6 ENSRNA049462227-T1_13601133_3 - 0.021 14.8 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Paired-box protein 2 C terminal Quaking_NLS PF16551.3 Gasu_nc0019-1_23309130_3 - 0.067 12.7 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking tRNA_bind PF01588.18 HannXRQ_Chr16g0509321-1_25201107_2 - 0.19 11.7 0.1 13 5.9 0.0 2.0 2 0 0 2 2 2 0 Putative tRNA binding domain RRM_7 PF16367.3 HannXRQ_Chr03g0075451-1_25204107_2 - 0.044 13.8 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.20 HannXRQ_Chr03g0075451-1_25204107_2 - 0.067 12.9 0.2 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S17 PF00366.18 HannXRQ_Chr05g0137281-1_25202107_3 - 8.3e-08 32.1 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Adeno_PV PF03910.11 HannXRQ_Chr00c0194g0572461-1_25201107_3 - 0.047 12.2 2.6 0.059 11.9 2.6 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Shugoshin_C PF07557.9 ENSRNA049483726-T1_26304130_3 - 0.13 11.9 2.0 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 Shugoshin C terminus YobH PF13996.4 EPlLPET00000000722_27901107_2 - 0.067 13.1 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 YobH-like protein PriCT_1 PF08708.9 ENSRNA049460055-T1_33201126_3 - 0.083 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) PMP1_2 PF08114.9 ENSRNA049459395-T1_33201126_1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase proteolipid family PRIMA1 PF16101.3 EPlOBRT00000001055_38101106_2 - 0.0054 16.6 0.6 0.0068 16.3 0.6 1.2 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 DUF1049 PF06305.9 EPlOGLT00000023818_38201133_1 - 0.014 15.0 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) OATP PF03137.18 EPlOGLT00000023818_38201133_1 - 0.087 11.0 0.6 0.092 10.9 0.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2140 PF09911.7 EPlOGLT00000023818_38201133_1 - 0.17 11.3 0.1 0.2 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) MNSV_P7B PF06692.9 EPlOGLuT00000001392_38301122_3 - 0.11 12.4 1.3 0.15 11.9 1.0 1.4 1 1 0 1 1 1 0 Melon necrotic spot virus P7B protein Lipocalin_5 PF13924.4 EPlOGLuT00000001944_38301122_2 - 0.11 12.1 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Lipocalin-like domain DivIVA PF05103.11 EPlOINT00000034109_38401130_1 - 0.0046 16.9 0.2 0.0053 16.7 0.2 1.1 1 0 0 1 1 1 1 DivIVA protein ATP-synt_B PF00430.16 EPlOINT00000034109_38401130_1 - 0.034 14.1 0.2 0.042 13.8 0.2 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Lant_dehydr_C PF14028.4 ENSRNA049476857-T1_38501139_1 - 0.0098 15.3 0.1 0.0098 15.3 0.1 1.0 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term DUF4131 PF13567.4 NCRNA_1104_38601107_3 - 3.1 7.2 6.4 3.7 7.0 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) fn3_2 PF16893.3 EPlOPUT00000000261_38801122_3 - 0.079 13.0 0.2 3.7 7.6 0.1 2.1 2 0 0 2 2 2 0 Fibronectin type III domain H2TH PF06831.12 EPlOPUT00000004825_38801122_3 - 0.14 12.0 1.0 13 5.8 0.3 2.1 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain DUF3613 PF12266.6 EPlORUT00000001076_38901107_3 - 0.18 11.5 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Tir_receptor_N PF07490.9 EPlORUT00000001433_38901107_1 - 0.06 13.0 0.0 0.074 12.7 0.0 1.0 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus RVT_1 PF00078.25 ENSRNA049472083-T1_38901110_1 - 0.034 13.5 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF755 PF05501.9 EPlOSAT00000005060_39001107_3 - 0.16 12.2 8.7 0.18 12.0 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ETRAMP PF09716.8 EPlOSAT00000014774_39001107_1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Protocadherin PF08374.9 EPlOSAT00000018475_39001107_1 - 0.81 9.5 4.8 1 9.2 4.8 1.2 1 0 0 1 1 1 0 Protocadherin Shugoshin_C PF07557.9 EPlOSAT00000021265_39004107_3 - 3.6 7.3 5.6 0.43 10.3 0.1 2.2 2 0 0 2 2 2 0 Shugoshin C terminus LpxB PF02684.13 EPlOSAT00000045367_39001107_3 - 0.12 11.1 0.8 0.13 10.9 0.8 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Opiods_neuropep PF01160.16 ENSRNA049454171-T1_42101133_3 - 0.071 13.1 1.8 4.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide DUF702 PF05142.10 ENSRNA049453238-T1_42101133_2 - 0.00049 20.5 2.9 0.00063 20.1 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF702) DUF702 PF05142.10 ENSRNA049453227-T1_42101133_2 - 0.00049 20.5 2.9 0.00063 20.1 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF702) SH3_9 PF14604.4 ENSRNA049494690-T1_43703130_2 - 0.053 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain DUF4500 PF14937.4 ENSRNA049466148-T1_47501130_3 - 0.12 12.3 0.6 0.18 11.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Phage_TAC_6 PF09550.8 ENSRNA049460759-T1_47501130_1 - 0.053 13.8 0.2 0.077 13.3 0.2 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC DUF1737 PF08410.8 ENSRNA049455076-T1_47502130_2 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Prok-RING_1 PF14446.4 ENSRNA049453371-T1_47501130_3 - 1.8 8.4 5.8 0.61 9.9 3.1 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Shugoshin_C PF07557.9 ENSRNA049453754-T1_48004130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049453710-T1_48004130_3 - 1.4 8.6 6.7 0.48 10.1 0.1 2.4 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049453672-T1_48004130_2 - 1.3 8.8 6.7 0.48 10.1 0.1 2.5 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049453659-T1_48004130_2 - 3.1 7.5 5.6 0.48 10.1 0.1 2.4 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049453603-T1_48004130_2 - 1.3 8.8 6.7 0.48 10.1 0.1 2.5 2 0 0 2 2 2 0 Shugoshin C terminus CCER1 PF15482.4 ENSRNA049454774-T1_48001140_2 - 0.39 10.4 5.9 0.42 10.3 5.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Endonuclease_5 PF04493.12 ENSRNA049462987-T1_48603130_2 - 0.04 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Endonuclease V DUF3151 PF11349.6 ENSRNA049455615-T1_48601140_3 - 0.039 13.9 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) Shugoshin_C PF07557.9 ENSRNA049485570-T1_48904130_3 - 0.014 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049485541-T1_48904130_2 - 4.3 7.1 5.6 0.48 10.1 0.1 2.2 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049484584-T1_48904130_2 - 4.3 7.1 5.6 0.48 10.1 0.1 2.2 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049484582-T1_48904130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049484573-T1_48904130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049484566-T1_48904130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049484547-T1_48904130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049484545-T1_48904130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049483662-T1_48904130_2 - 3.3 7.4 5.6 0.48 10.1 0.1 2.4 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049483655-T1_48904130_3 - 4.4 7.1 5.6 0.48 10.1 0.1 2.2 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049483650-T1_48904130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_C PF07557.9 ENSRNA049483575-T1_48904130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus DUF1648 PF07853.9 ENSRNA049466171-T1_50701126_2 - 0.042 13.4 0.8 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) Gallidermin PF02052.13 ENSRNA049462820-T1_50701126_2 - 0.08 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Gallidermin RVT_3 PF13456.4 ENSRNA049475508-T1_51701126_3 - 0.0034 16.9 0.1 0.0039 16.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like NfI_DNAbd_pre-N PF10524.7 ENSRNA049473768-T1_51701140_2 - 0.11 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Toxin_3 PF00537.16 TRIAE_CS42_7DL_TGACv1_603411_AA1983110.1_51802107_2 - 0.054 13.6 11.7 0.09 12.8 11.7 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain Abhydrolase_2 PF02230.14 TRIAE_CS42_U_TGACv1_642243_AA2114140.1_51802107_2 - 0.12 12.1 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CRAL_TRIO PF00650.18 TRIAE_CS42_5AL_TGACv1_374624_AA1204780.1_51806107_1 - 0.0093 15.6 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain AC_N PF16214.3 TRIAE_CS42_5BL_TGACv1_406674_AA1348520.1_51803107_3 - 3.7 6.4 7.7 3.7 6.4 6.8 1.4 1 1 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TPPII_N PF12583.6 TRIAE_CS42_2DS_TGACv1_177582_AA0580560.1_51801107_2 - 0.044 14.2 1.0 0.058 13.8 1.0 1.1 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Shugoshin_C PF07557.9 ENSRNA049476492-T1_51904130_2 - 5.5 6.7 5.9 0.48 10.1 0.1 2.2 2 0 0 2 2 2 0 Shugoshin C terminus Baculo_VP1054 PF05789.9 ENSRNA049469640-T1_53002130_3 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus VP1054 protein Shugoshin_C PF07557.9 ENSRNA049478799-T1_53704130_3 - 4.6 7.0 5.6 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin C terminus DUF2393 PF09624.8 Zm00001d022656_T001_53701102_1 - 0.056 13.2 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF3099 PF11298.6 Zm00001d022799_T001_53701102_2 - 0.09 12.8 2.4 0.16 12.0 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) DARPP-32 PF05395.10 ENSACAT00000035344.1_02201102_3 - 0.00015 21.9 0.0 0.00021 21.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 ACT_6 PF13740.4 ENSACAT00000031618.1_02201102_3 - 0.043 13.7 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 ACT domain DUF503 PF04456.10 ENSACAT00000033293.1_02202102_1 - 0.021 14.5 0.4 0.03 14.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF503) DIRP PF06584.11 ENSACAT00000033293.1_02202102_1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 DIRP Activin_recp PF01064.21 ENSACAT00000031787.1_02202102_3 - 3.6 8.6 11.2 8.5 7.4 11.2 1.6 1 1 0 1 1 1 0 Activin types I and II receptor domain DUF1658 PF07871.9 ENSANAT00000060845.1_02602102_3 - 0.094 12.5 1.6 1.5 8.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1658) MscS_porin PF12795.5 ENSAMXT00000028250.1_04102102_2 - 0.0029 17.0 4.8 0.0029 17.0 4.8 1.4 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain DUF3552 PF12072.6 ENSAMXT00000028250.1_04102102_2 - 0.0066 15.8 20.6 0.0066 15.8 20.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.13 ENSAMXT00000028250.1_04102102_2 - 0.047 13.1 8.2 0.065 12.7 8.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.11 ENSAMXT00000028250.1_04102102_2 - 0.8 8.1 2.6 1.2 7.6 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) EVI2A PF05399.9 ENSAMXT00000028151.1_04105102_1 - 0.058 12.9 0.4 0.089 12.2 0.4 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) TMIE PF16038.3 ENSAMXT00000028151.1_04105102_1 - 1.3 8.8 4.0 3.7 7.4 4.0 1.7 1 0 0 1 1 1 0 TMIE protein Tmemb_9 PF05434.9 ENSAMXT00000028151.1_04105102_3 - 2.1 8.1 6.3 3.6 7.3 6.3 1.3 1 0 0 1 1 1 0 TMEM9 TMEM154 PF15102.4 ENSAMXT00000029178.1_04106102_1 - 0.011 15.5 0.9 0.044 13.6 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family PAG PF15347.4 ENSAMXT00000028736.1_04101102_1 - 0.087 11.7 0.3 0.12 11.3 0.3 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched PRIMA1 PF16101.3 ENSAMXT00000028197.1_04102102_1 - 0.97 9.3 6.3 0.29 11.0 2.5 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mrr_N PF14338.4 ENSAMXT00000028768.1_04101102_1 - 0.052 13.6 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 Mrr N-terminal domain I-set PF07679.14 ENSAMXT00000028481.1_04105102_3 - 8.5e-08 32.0 1.9 2 8.4 0.0 5.4 6 0 0 6 6 6 3 Immunoglobulin I-set domain Ig_3 PF13927.4 ENSAMXT00000028481.1_04105102_3 - 6.2e-07 29.8 4.9 11 6.5 0.1 5.6 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.15 ENSAMXT00000028481.1_04105102_3 - 7.3e-06 26.0 6.9 15 5.7 0.1 5.5 6 0 0 6 6 6 5 Immunoglobulin V-set domain ig PF00047.23 ENSAMXT00000028481.1_04105102_3 - 0.00083 19.4 2.2 54 3.9 0.0 5.0 5 0 0 5 5 5 0 Immunoglobulin domain KASH_CCD PF14662.4 ENSAMXT00000028573.1_04102102_2 - 0.0021 17.8 3.6 0.0031 17.2 3.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DivIC PF04977.13 ENSAMXT00000028573.1_04102102_2 - 0.013 15.1 2.5 0.023 14.3 2.5 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.13 ENSAMXT00000028573.1_04102102_2 - 0.21 11.5 8.8 0.36 10.8 8.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Humanin PF15040.4 ENSBTAT00000060540.1_06504123_1 - 4.1e-13 48.4 0.0 7.2e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Humanin family Mdv1 PF11542.6 ENSBTAT00000060718.1_06501106_1 - 0.076 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial division protein 1 Ribosomal_L26 PF16906.3 H01G02.8_07601107_3 - 0.03 14.7 0.3 0.044 14.2 0.3 1.2 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal CitX PF03802.12 T28F4.7_07601107_3 - 0.1 12.2 2.5 0.12 12.0 2.5 1.1 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Mdv1 PF11542.6 F11D5.31_07601107_1 - 0.016 15.1 0.3 0.023 14.5 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial division protein 1 SNARE PF05739.17 ENSCJAT00000047894.2_08001133_2 - 2.3 8.2 4.0 3.9 7.4 4.0 1.4 1 0 0 1 1 1 0 SNARE domain Humanin PF15040.4 ENSCHIT00000000004.1_09004123_3 - 1.9e-12 46.3 0.0 3.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Humanin family FATC PF02260.18 ENSCHIT00000009051.1_09002102_2 - 0.032 13.9 0.9 0.07 12.8 0.9 1.6 1 0 0 1 1 1 0 FATC domain MerE PF05052.10 ENSTSYT00000023070.2_09601133_2 - 0.12 12.2 0.4 0.17 11.7 0.4 1.2 1 0 0 1 1 1 0 MerE protein DUF3787 PF12655.5 ENSTSYT00000046715.1_09601106_2 - 0.078 12.8 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) QSregVF PF13652.4 ENSCAPT00000001178.1_09801106_1 - 0.18 11.7 0.0 0.24 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Lpp-LpqN PF10738.7 ENSCAPT00000002161.1_09801106_2 - 0.12 11.7 0.2 0.18 11.1 0.2 1.2 1 0 0 1 1 1 0 Probable lipoprotein LpqN Aquarius_N PF16399.3 ENSCPOT00000046109.1_09902102_2 - 8e-105 351.5 0.0 9.8e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus DUF3400 PF11880.6 ENSCPOT00000046109.1_09902102_2 - 0.076 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) HI0933_like PF03486.12 ENSCPOT00000038843.1_09903102_1 - 0.28 9.7 0.6 0.38 9.2 0.6 1.1 1 0 0 1 1 1 0 HI0933-like protein Myosin_head PF00063.19 ENSCPOT00000045784.1_09901102_2 - 0.011 13.9 0.0 0.013 13.6 0.0 1.0 1 0 0 1 1 1 0 Myosin head (motor domain) PTR PF12789.5 ENSCPOT00000028546.2_09901106_2 - 0.092 12.7 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Phage tail repeat like MSA-2c PF12238.6 ENSCCAT00000058595.1_10001102_1 - 0.09 12.6 2.5 0.11 12.4 2.5 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c zf-GRF PF06839.10 ENSCATT00000070716.1_10804102_1 - 2.2e-05 24.3 4.0 2.2e-05 24.3 4.0 2.5 2 0 0 2 2 2 1 GRF zinc finger Toxin_31 PF08119.9 ENSCATT00000070716.1_10804102_1 - 0.048 13.3 0.3 0.13 11.9 0.3 1.7 1 0 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family PT PF04886.10 ENSCATT00000070837.1_10805102_2 - 0.16 11.4 0.6 0.25 10.8 0.6 1.3 1 0 0 1 1 1 0 PT repeat Vitelline_membr PF10542.7 ENSCATT00000071322.1_10804102_2 - 0.087 12.6 1.9 13 5.6 0.8 2.4 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region zf-U11-48K PF05253.10 ENSCATT00000070608.1_10801102_2 - 4 7.3 8.1 7.3 6.5 1.3 2.8 2 1 0 2 2 2 0 U11-48K-like CHHC zinc finger DUF2933 PF11666.6 ENSCATT00000070781.1_10801102_3 - 2.2 8.2 8.7 5.3 7.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) Thiol-ester_cl PF10569.7 ENSCATT00000003095.1_10801106_3 - 0.1 12.2 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region Fer4_20 PF14691.4 ENSCLAT00000033921.1_11302102_3 - 0.24 11.1 0.2 0.24 11.1 0.2 1.4 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF4791 PF16039.3 ENSCLAT00000035270.1_11302102_2 - 0.089 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) S1FA PF04689.11 ENSCLAT00000035270.1_11302102_2 - 0.19 11.8 1.1 0.43 10.6 0.2 1.9 2 0 0 2 2 2 0 DNA binding protein S1FA BST2 PF16716.3 ENSCLAT00000037383.1_11303102_1 - 6.8e-16 58.5 12.4 1.4e-14 54.3 7.2 2.2 2 0 0 2 2 2 2 Bone marrow stromal antigen 2 AIP3 PF03915.11 ENSCLAT00000037383.1_11303102_1 - 0.011 14.8 0.2 0.015 14.3 0.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Med9 PF07544.11 ENSCLAT00000037383.1_11303102_1 - 0.015 15.3 4.1 2.3 8.3 0.9 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CENP-Q PF13094.4 ENSCLAT00000037383.1_11303102_1 - 0.016 15.3 1.3 0.027 14.5 1.3 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CwsA PF10814.6 ENSCLAT00000037383.1_11303102_1 - 0.022 14.8 1.2 0.065 13.3 1.2 1.8 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA HisKA_3 PF07730.11 ENSCLAT00000037383.1_11303102_1 - 0.026 14.9 1.2 2.8 8.4 0.2 2.4 2 0 0 2 2 2 0 Histidine kinase Mnd1 PF03962.13 ENSCLAT00000037383.1_11303102_1 - 0.1 12.4 1.2 0.16 11.7 1.2 1.2 1 0 0 1 1 1 0 Mnd1 family JAKMIP_CC3 PF16034.3 ENSCLAT00000037383.1_11303102_1 - 0.36 10.6 7.3 0.041 13.7 3.0 1.6 2 0 0 2 2 2 0 JAKMIP CC3 domain CCDC-167 PF15188.4 ENSCLAT00000037383.1_11303102_1 - 0.49 10.6 1.9 1.1 9.6 1.9 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DivIVA PF05103.11 ENSCLAT00000037383.1_11303102_1 - 0.6 10.1 5.0 0.66 9.9 1.9 2.0 2 0 0 2 2 2 0 DivIVA protein ApoLp-III PF07464.9 ENSCLAT00000037383.1_11303102_1 - 0.84 9.6 9.0 1.6 8.7 5.2 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.10 ENSCLAT00000037383.1_11303102_1 - 1.8 8.5 5.0 1.2 9.0 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.16 ENSCLAT00000037383.1_11303102_1 - 2.2 8.0 9.6 1 9.1 4.8 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Syntaxin-6_N PF09177.9 ENSCLAT00000037383.1_11303102_1 - 2.8 8.4 5.4 17 5.9 5.4 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal KASH_CCD PF14662.4 ENSCLAT00000037383.1_11303102_1 - 6.4 6.4 9.9 9.7 5.9 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH THOC7 PF05615.11 ENSCLAT00000037383.1_11303102_1 - 7.4 6.7 9.1 28 4.9 9.2 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 IncA PF04156.12 ENSCLAT00000037383.1_11303102_1 - 9.8 5.8 9.0 15 5.2 4.4 2.0 2 0 0 2 2 2 0 IncA protein zf-CDGSH PF09360.8 ENSCLAT00000038282.1_11301102_1 - 0.14 12.3 0.1 0.14 12.3 0.1 1.8 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type Thiol-ester_cl PF10569.7 ENSCSAT00000021862.1_11701106_2 - 0.089 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region DUF3930 PF13067.4 ENSCSAT00000026903.1_11701106_2 - 0.011 15.6 0.4 0.015 15.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) zinc_ribbon_12 PF11331.6 ENSCINT00000030117.1_12401106_2 - 0.039 13.6 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon domain DUF3039 PF11238.6 ENSCSAVT00000020974.1_12501106_3 - 0.14 11.8 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) HMG_box_5 PF14887.4 ENSCANT00000000385.1_13201133_1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Gemini_AC4_5 PF04807.10 ENSCANT00000018344.1_13201106_1 - 0.12 12.0 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Plasmod_MYXSPDY PF07981.9 ENSCGRT00001001913.1_14301106_1 - 0.054 13.5 0.0 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 Plasmodium repeat_MYXSPDY Defensin_2 PF01097.16 ENSCGRT00001006712.1_14301106_3 - 0.075 12.9 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Arthropod defensin LpxB PF02684.13 ENSCGRT00000031806.1_14402102_1 - 0.26 10.0 0.3 0.37 9.4 0.3 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Peptidase_M49 PF03571.13 ENSCGRT00000031939.1_14403102_3 - 0.14 10.4 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M49 Gsf2 PF11055.6 ENSCGRT00000032973.1_14402102_3 - 0.22 10.1 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 IncA PF04156.12 ENSCGRT00000033494.1_14401102_2 - 3.4e-05 23.6 4.0 4.7e-05 23.1 4.0 1.2 1 0 0 1 1 1 1 IncA protein Atg14 PF10186.7 ENSCGRT00000033494.1_14401102_2 - 0.0018 17.3 7.6 0.0022 17.0 7.6 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_N PF15905.3 ENSCGRT00000033494.1_14401102_2 - 0.1 11.9 19.0 0.12 11.7 19.0 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal BcrAD_BadFG PF01869.18 ENSCGRT00000033494.1_14401102_2 - 0.15 11.4 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF724 PF05266.12 ENSCGRT00000033494.1_14401102_2 - 0.25 11.0 12.0 0.36 10.5 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF16 PF01519.14 ENSCGRT00000033494.1_14401102_2 - 1.5 9.2 14.6 1.6 9.1 11.5 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 TPR_14 PF13428.4 ENSCGRT00000033574.1_14401102_2 - 0.0019 18.7 2.6 1.1 10.1 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.4 ENSCGRT00000033574.1_14401102_2 - 0.002 18.3 3.4 0.0027 17.8 2.6 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.4 ENSCGRT00000033574.1_14401102_2 - 0.0021 18.6 1.1 0.22 12.1 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.4 ENSCGRT00000033574.1_14401102_2 - 0.0043 17.0 0.3 1.1 9.5 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.26 ENSCGRT00000033574.1_14401102_2 - 0.13 12.0 0.3 23 4.9 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC2_membrane PF01061.22 ENSCGRT00000034139.1_14401102_3 - 0.013 14.8 0.6 0.021 14.1 0.6 1.3 1 0 0 1 1 1 0 ABC-2 type transporter Glycophorin_A PF01102.16 ENSCGRT00000034139.1_14401102_3 - 0.16 12.0 0.8 0.31 11.2 0.4 1.5 2 0 0 2 2 2 0 Glycophorin A UBN_AB PF14075.4 ENSCGRT00000034409.1_14401102_1 - 0.21 11.2 0.1 0.26 10.9 0.1 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF2180 PF09947.7 ENSCGRT00000031144.1_14401106_1 - 0.049 13.5 0.3 0.068 13.0 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) V-set PF07686.15 ENSDART00000137730.2_16102114_3 - 2.4e-12 46.9 0.4 5.6e-11 42.4 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.4 ENSDART00000137730.2_16102114_3 - 6.5e-09 36.2 3.8 5.7e-06 26.7 0.3 2.7 2 1 1 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.4 ENSDART00000137730.2_16102114_3 - 1.8e-07 31.3 6.0 0.0019 18.4 1.3 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 ENSDART00000137730.2_16102114_3 - 0.00026 20.9 0.1 0.016 15.1 0.0 3.0 1 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.23 ENSDART00000137730.2_16102114_3 - 0.00076 19.5 4.0 0.31 11.1 0.4 3.4 2 2 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.13 ENSDART00000137730.2_16102114_3 - 0.0046 17.3 0.9 0.21 12.0 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin C1-set domain V-set_2 PF15910.3 ENSDART00000137730.2_16102114_3 - 0.018 15.0 2.4 0.091 12.7 0.2 2.4 1 1 1 2 2 2 0 ICOS V-set domain SLX9 PF15341.4 ENSDART00000135802.2_16102103_3 - 8.3e-07 29.4 0.5 8.3e-07 29.4 0.5 1.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 MSA-2c PF12238.6 ENSDNOT00000055134.1_16201102_3 - 0.83 9.5 7.0 0.87 9.4 7.0 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c CEBP_ZZ PF16366.3 ENSDNOT00000056078.1_16201102_2 - 0.046 13.8 3.2 0.094 12.8 3.2 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1179 PF06678.9 ENSDNOT00000054659.1_16206102_2 - 0.16 11.9 0.7 0.31 10.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) DUF1772 PF08592.9 ENSDNOT00000053780.1_16203102_2 - 2.1 8.5 6.5 4.7 7.4 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) YfhO PF09586.8 ENSDNOT00000053780.1_16203102_2 - 3.4 5.6 7.3 4.2 5.3 7.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO zf-RING_UBOX PF13445.4 ENSDNOT00000054475.1_16203102_2 - 0.38 10.7 4.5 0.16 11.9 0.9 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Cytochrom_B_N_2 PF13631.4 ENSDNOT00000056378.1_16202102_2 - 0.022 14.6 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Defensin_4 PF07936.10 ENSDORT00000020769.2_17101106_3 - 0.32 10.8 2.4 17 5.2 0.1 2.8 3 0 0 3 3 3 0 Potassium-channel blocking toxin PEHE PF15275.4 FBtr0346997_18502107_2 - 0.023 15.2 0.7 0.032 14.7 0.7 1.3 1 0 0 1 1 1 0 PEHE domain Ribosomal_S4e PF00900.18 FBtr0343736_18502107_3 - 0.14 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal family S4e BTP PF05232.10 FBtr0310084_18502107_2 - 0.18 11.7 1.6 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Chlorhexidine efflux transporter Ser_hydrolase PF06821.11 FBtr0335265_18502107_1 - 0.069 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase Trp_oprn_chp PF09534.8 FBtr0344698_18503107_2 - 0.26 10.9 12.1 0.4 10.3 12.1 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DIM PF08194.10 FBtr0345233_18502107_1 - 0.017 15.2 1.5 0.031 14.4 1.5 1.4 1 0 0 1 1 1 0 DIM protein ArfGap PF01412.16 ENSETET00000024625.1_20301106_3 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf CAP_N PF01213.17 ENSETET00000026670.1_20301106_3 - 0.41 9.9 2.0 0.43 9.9 2.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-ISL3 PF14690.4 ENSEEUT00000021709.1_21201106_3 - 0.021 15.3 0.6 0.042 14.3 0.6 1.4 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 UPF0506 PF11703.6 ENSEEUT00000019668.1_21201106_2 - 0.11 12.8 1.2 0.86 9.9 1.6 1.9 1 1 1 2 2 2 0 UPF0506 ESPR PF13018.4 ENSFCAT00000050084.1_22401106_2 - 0.17 11.6 0.4 0.28 10.9 0.4 1.4 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system Phage_integ_N PF09003.8 ENSFCAT00000033789.1_22401106_3 - 0.035 14.1 0.2 0.058 13.4 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage lambda integrase, N-terminal domain ASH PF15780.3 ENSFALT00000022232.1_22502102_3 - 0.00095 19.2 0.1 0.015 15.4 0.0 2.4 1 1 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF4672 PF15716.3 ENSFALT00000024347.1_22501102_2 - 0.1 12.1 1.7 0.14 11.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) PRIMA1 PF16101.3 ENSFALT00000021579.1_22502102_3 - 0.28 11.1 22.0 0.61 10.0 22.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1430 PF07242.9 ENSFALT00000022485.1_22501102_3 - 0.085 13.0 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) C1_1 PF00130.20 ENSFALT00000018313.1_22501102_1 - 0.013 15.2 2.0 0.013 15.2 2.0 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) gag_pre-integrs PF13976.4 ENSFALT00000018313.1_22501102_1 - 8 6.3 8.2 1.8 8.4 0.5 2.7 2 1 0 2 2 2 0 GAG-pre-integrase domain RCC1_2 PF13540.4 ENSFALT00000018549.1_22503102_2 - 0.00042 19.9 6.2 0.83 9.4 0.1 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat 1-cysPrx_C PF10417.7 ENSFALT00000024123.1_22503102_3 - 0.31 10.8 6.2 18 5.1 0.1 3.4 3 0 0 3 3 3 0 C-terminal domain of 1-Cys peroxiredoxin CfAFP PF05264.9 ENSFDAT00000035296.1_22901102_1 - 0.034 14.0 0.6 0.041 13.7 0.6 1.1 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) Tnp_zf-ribbon_2 PF13842.4 ENSFDAT00000036259.1_22908102_1 - 0.015 15.9 8.3 0.015 15.9 8.3 3.1 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon SR-25 PF10500.7 ENSFDAT00000040464.1_22907102_1 - 0.13 11.8 12.9 0.21 11.0 12.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ETRAMP PF09716.8 ENSFDAT00000040464.1_22907102_2 - 0.07 13.1 3.6 0.2 11.6 3.6 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SR-25 PF10500.7 ENSFDAT00000040464.1_22907102_2 - 2.6 7.5 15.8 4.2 6.8 15.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.8 ENSFDAT00000040464.1_22907102_3 - 1.2 9.0 5.7 2.1 8.3 5.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2678 PF10856.6 ENSGMOT00000023471.1_23201122_2 - 0.0077 16.0 5.5 0.011 15.6 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Pox_G9-A16 PF03003.14 ENSGALT00000088602.1_23502102_2 - 0.18 11.4 3.0 0.3 10.7 3.0 1.3 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 SRCR PF00530.16 ENSGALT00000084766.1_23503102_1 - 2e-07 31.3 0.4 3.6e-07 30.5 0.4 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF3934 PF13070.4 ENSGALT00000084766.1_23503102_2 - 0.0023 18.2 1.2 0.0023 18.2 1.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3934) SRCR PF00530.16 ENSGALT00000084766.1_23503102_3 - 1e-62 208.7 29.2 2e-31 108.3 9.2 3.3 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.4 ENSGALT00000084766.1_23503102_3 - 1.5e-10 41.3 11.5 0.00035 20.9 1.4 3.4 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SH3_9 PF14604.4 ENSGALT00000078022.2_23503102_1 - 2.1e-05 24.2 0.1 3.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 ENSGALT00000078022.2_23503102_1 - 0.00075 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 ENSGALT00000078022.2_23503102_1 - 0.0071 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain MPS2 PF17060.3 ENSGALT00000078022.2_23503102_2 - 0.12 11.5 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 SH3_1 PF00018.26 ENSGALT00000084468.1_23505102_2 - 5.2e-10 38.6 0.0 1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 ENSGALT00000084468.1_23505102_2 - 2.5e-06 27.1 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 ENSGALT00000084468.1_23505102_2 - 6.6e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.9 ENSGALT00000084468.1_23505102_2 - 0.0021 18.2 0.2 0.0044 17.1 0.2 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SAM_PNT PF02198.14 ENSGALT00000084468.1_23505102_2 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain CAP_N PF01213.17 ENSGALT00000051968.1_23505102_1 - 0.076 12.4 6.8 0.1 11.9 6.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.9 ENSGALT00000051968.1_23505102_1 - 1.1 9.2 4.6 1.7 8.5 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Humanin PF15040.4 ENSGACT00000027715.1_23604123_1 - 8.9e-06 25.0 0.0 1.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Humanin family Peptidase_S15 PF02129.16 ENSGGOT00000069326.1_24201102_2 - 0.12 11.8 3.5 0.17 11.3 3.5 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RR_TM4-6 PF06459.10 ENSGGOT00000069326.1_24201102_2 - 0.48 10.1 18.3 0.58 9.8 18.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.13 ENSGGOT00000069326.1_24201102_2 - 1.3 7.7 3.6 1.6 7.5 3.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) MIP-T3 PF10243.7 ENSGGOT00000069326.1_24201102_2 - 1.3 7.5 28.7 1.7 7.1 28.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 O-antigen_lig PF13425.4 ENSGGOT00000069326.1_24201102_2 - 1.5 7.4 3.5 1.8 7.1 3.5 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ALMT PF11744.6 ENSGGOT00000069326.1_24201102_2 - 6 5.5 14.7 7.3 5.2 14.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Atg14 PF10186.7 ENSGGOT00000069326.1_24201102_2 - 6.3 5.6 18.7 7.7 5.4 18.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CAF1 PF04857.18 ENSGGOT00000069326.1_24201102_2 - 6.7 5.7 8.9 8.1 5.4 8.9 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Sel1 PF08238.10 ENSGGOT00000069418.1_24201102_1 - 3e-05 24.4 0.0 8.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Sel1 repeat DUF3778 PF12620.6 ENSHGLT00000035588.1_25709102_1 - 0.13 11.7 1.5 0.38 10.2 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) Tfb2 PF03849.12 ENSHGLT00000036754.1_25701102_3 - 0.13 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 LTP_2 PF14368.4 ENSHGLT00000041259.1_25701102_2 - 0.014 15.4 0.2 0.017 15.1 0.2 1.2 1 0 0 1 1 1 0 Probable lipid transfer DUF1403 PF07183.9 ENSHGLT00000041259.1_25701102_2 - 0.046 13.1 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) IQ PF00612.25 ENSHGLT00100036532.1_25803102_1 - 0.13 12.0 0.5 0.34 10.7 0.5 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif zf-CCHC_3 PF13917.4 ENST00000640770.1_26202102_1 - 6.5 6.7 11.9 31 4.5 0.2 4.0 1 1 3 4 4 4 0 Zinc knuckle LRR_8 PF13855.4 ENST00000599308.3_26202114_1 - 0.00023 20.7 2.4 0.00042 19.9 2.4 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.5 ENST00000599308.3_26202114_1 - 0.00071 19.8 1.9 0.0014 18.8 1.9 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_4 PF12799.5 ENST00000599308.3_26202114_2 - 0.00081 19.6 1.2 0.62 10.4 1.0 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 ENST00000599308.3_26202114_2 - 0.0036 16.9 1.2 0.26 11.0 0.2 2.3 2 0 0 2 2 2 2 Leucine rich repeat BTK PF00779.17 ENSSTOT00000037240.1_26703102_1 - 0.9 9.3 5.2 2.9 7.6 0.3 2.4 2 0 0 2 2 2 0 BTK motif DUF3553 PF12073.6 ENSSTOT00000009466.3_26702102_1 - 0.079 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) DUF4392 PF14336.4 ENSSTOT00000009466.3_26702102_3 - 1.2e-06 28.0 0.0 1.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.10 ENSSTOT00000009466.3_26702102_3 - 6.3e-06 26.1 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) HAUS-augmin3 PF14932.4 ENSSTOT00000038168.1_26701102_2 - 0.26 10.6 12.7 0.31 10.4 12.7 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ADIP PF11559.6 ENSSTOT00000038168.1_26701102_2 - 0.27 11.2 13.9 0.44 10.5 13.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.3 ENSSTOT00000038168.1_26701102_2 - 0.39 11.2 13.9 0.055 13.9 8.4 1.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NUC194 PF08163.10 ENSSTOT00000038168.1_26701102_2 - 0.47 9.5 5.7 0.97 8.5 5.7 1.5 1 1 0 1 1 1 0 NUC194 domain ERM PF00769.17 ENSSTOT00000038168.1_26701102_2 - 0.68 9.6 15.2 0.78 9.4 15.2 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.6 ENSSTOT00000038168.1_26701102_2 - 0.95 9.4 21.9 0.23 11.3 6.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.9 ENSSTOT00000038168.1_26701102_2 - 1.6 7.4 13.1 1.9 7.1 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6 PF04111.10 ENSSTOT00000038168.1_26701102_2 - 2 7.6 13.8 2.4 7.3 13.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF641 PF04859.10 ENSSTOT00000038168.1_26701102_2 - 3 8.1 11.7 0.33 11.1 4.8 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.4 ENSSTOT00000038168.1_26701102_2 - 7.6 5.6 7.0 14 4.8 7.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec2p PF06428.9 ENSSTOT00000038168.1_26701102_2 - 7.7 6.4 16.1 0.51 10.2 4.7 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p TraU PF06834.9 ENSLACT00000022677.1_27801106_3 - 0.087 11.9 0.2 0.095 11.8 0.2 1.1 1 0 0 1 1 1 0 TraU protein CEND1 PF15677.3 ENSLOCT00000027235.1_28108102_2 - 6.7e-06 26.6 6.1 1.2e-05 25.7 6.1 1.4 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 TruB_C PF09142.9 ENSLOCT00000025583.1_28102102_1 - 0.022 14.4 4.0 0.099 12.3 1.3 3.1 1 1 1 2 2 2 0 tRNA Pseudouridine synthase II, C terminal TRAPPC9-Trs120 PF08626.9 ENSLOCT00000026511.1_28103102_2 - 0.27 8.4 0.4 0.35 8.0 0.4 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit V-set PF07686.15 ENSLOCT00000026098.1_28104102_1 - 0.026 14.5 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain PulG PF11773.6 ENSLOCT00000026098.1_28104102_1 - 0.18 11.6 0.0 0.79 9.5 0.0 1.9 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Moricin PF06451.9 ENSLOCT00000026473.1_28102102_3 - 0.46 10.1 2.3 8.2 6.1 0.2 2.4 2 0 0 2 2 2 0 Moricin Humanin PF15040.4 ENSLAFT00000038038.1_29204123_2 - 9.4e-08 31.3 0.0 1.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Humanin family RS4NT PF08071.10 ENSLAFT00000037762.1_29201106_3 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 RS4NT (NUC023) domain Cas_CXXC_CXXC PF09706.8 ENSLAFT00000037598.1_29201106_3 - 0.048 13.8 0.1 0.048 13.8 0.1 1.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) NECFESHC PF16621.3 ENSMFAT00000071200.1_29502102_2 - 1.5 8.7 4.1 8.1 6.4 1.9 2.3 2 0 0 2 2 2 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 Antimicrobial25 PF16839.3 ENSMFAT00000071200.1_29502102_3 - 0.011 15.7 5.8 0.011 15.7 5.8 2.1 2 1 0 2 2 2 0 Nematode antimicrobial peptide Caveolin PF01146.15 ENSMFAT00000072033.1_29507102_2 - 0.14 12.0 0.3 0.25 11.2 0.3 1.2 1 0 0 1 1 1 0 Caveolin IncA PF04156.12 ENSMFAT00000071198.1_29508102_3 - 0.0086 15.8 0.9 0.014 15.0 0.9 1.2 1 0 0 1 1 1 1 IncA protein DUF4201 PF13870.4 ENSMFAT00000071198.1_29508102_3 - 0.034 13.7 3.3 0.07 12.6 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.9 ENSMFAT00000071198.1_29508102_3 - 0.18 10.5 1.3 0.28 9.9 1.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4404 PF14357.4 ENSMFAT00000071198.1_29508102_3 - 5.3 7.7 5.2 9.5 6.9 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF3944 PF13099.4 ENSMFAT00000071941.1_29502102_1 - 0.00081 19.1 0.1 2.5e+02 1.5 0.0 6.4 7 0 0 7 7 7 0 Domain of unknown function (DUF3944) Pcc1 PF09341.8 ENSMFAT00000071941.1_29502102_2 - 0.0035 17.3 5.6 1.3 9.0 2.7 3.1 1 1 1 2 2 2 2 Transcription factor Pcc1 ZZ PF00569.15 ENSMFAT00000071941.1_29502102_2 - 3.7 7.3 12.2 3.7 7.3 2.7 3.1 2 1 1 3 3 3 0 Zinc finger, ZZ type Pcc1 PF09341.8 ENSMFAT00000071941.1_29502102_3 - 2.9 8.0 4.5 10 6.2 4.5 1.9 1 1 0 1 1 1 0 Transcription factor Pcc1 SDP_N PF12278.6 ENSMFAT00000071941.1_29502102_3 - 6.3 6.3 21.3 5.3 6.6 3.2 3.5 1 1 1 3 3 3 0 Sex determination protein N terminal ALMS_motif PF15309.4 ENSMMUT00000076804.1_29602102_1 - 3.7e-07 30.5 4.6 6.4e-07 29.7 4.6 1.2 1 0 0 1 1 1 1 ALMS motif ALMS_motif PF15309.4 ENSMMUT00000076804.1_29602102_3 - 0.0045 17.2 2.0 0.0086 16.3 2.0 1.4 1 0 0 1 1 1 1 ALMS motif SUIM_assoc PF16619.3 ENSMMUT00000076804.1_29602102_3 - 0.12 12.3 2.8 0.11 12.4 1.2 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MerE PF05052.10 ENSMNET00000002190.1_29701133_3 - 0.026 14.3 0.1 0.036 13.9 0.1 1.2 1 0 0 1 1 1 0 MerE protein Spc7 PF08317.9 ENSMNET00000071242.1_29703102_1 - 0.11 11.2 7.1 0.18 10.5 7.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.12 ENSMNET00000071242.1_29703102_1 - 0.12 12.1 7.4 0.17 11.5 7.4 1.2 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.10 ENSMNET00000071242.1_29703102_1 - 0.27 11.1 2.5 0.42 10.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.6 ENSMNET00000071242.1_29703102_1 - 0.34 10.9 8.7 0.54 10.2 8.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ntox1 PF15500.4 ENSMNET00000071242.1_29703102_1 - 0.36 11.1 2.3 0.35 11.1 0.6 1.8 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 TBPIP PF07106.11 ENSMNET00000071242.1_29703102_1 - 1.7 8.2 11.0 0.77 9.4 6.9 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.10 ENSMNET00000071242.1_29703102_1 - 2.3 7.4 9.0 3.3 6.9 9.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4337 PF14235.4 ENSMNET00000071242.1_29703102_1 - 3 7.8 6.4 6 6.8 6.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Nsp1_C PF05064.11 ENSMNET00000071242.1_29703102_1 - 7.3 6.3 9.2 18 5.1 5.6 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region UPF0197 PF05251.10 ENSMNET00000071303.1_29707102_3 - 4.7 7.2 5.3 6.1 6.8 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0197) Yae1_N PF09811.7 ENSMNET00000070808.1_29709102_1 - 1.2 8.8 8.8 3.1 7.5 8.8 1.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal CENP-F_leu_zip PF10473.7 ENSMNET00000071674.1_29703102_2 - 0.05 13.5 0.1 0.078 12.9 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Thiol-ester_cl PF10569.7 ENSMNET00000011833.1_29701106_1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region Gemini_AC4_5 PF04807.10 ENSMLET00000000953.1_30101106_2 - 0.019 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region HTH_Tnp_ISL3 PF13542.4 ENSMGAT00000018254.1_30801133_2 - 0.0055 16.0 0.6 0.0089 15.3 0.2 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_CodY PF08222.9 ENSMAUT00000003272.1_31301106_3 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 CodY helix-turn-helix domain fn3 PF00041.19 ENSMICT00000072226.1_31505102_2 - 3.8e-06 27.0 0.3 0.00033 20.8 0.0 2.9 3 0 0 3 3 3 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.3 ENSMICT00000072226.1_31505102_2 - 0.012 16.0 0.0 0.031 14.7 0.0 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain DTW PF03942.13 ENSMICT00000071926.1_31505102_3 - 0.019 14.5 0.1 0.068 12.7 0.1 2.0 1 0 0 1 1 1 0 DTW domain DUF1400 PF07176.9 ENSMICT00000071926.1_31505102_3 - 0.53 10.5 4.2 0.56 10.4 0.7 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) MRP-S31 PF15433.4 ENSMICT00000071869.1_31509102_1 - 0.0016 18.1 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 MRP-S31 PF15433.4 ENSMICT00000071869.1_31509102_3 - 3.5e-09 36.7 2.5 5.2e-09 36.1 2.5 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 DUF865 PF05906.9 ENSMOCT00000007147.1_31901106_2 - 0.045 13.4 0.8 0.065 12.9 0.8 1.3 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) CLASP_N PF12348.6 ENSMODT00000051541.1_32301102_1 - 0.079 12.4 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 CLASP N terminal FSA_C PF10479.7 ENSMODT00000048741.1_32303102_3 - 4.2 5.3 5.5 5.5 4.8 5.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Rz1 PF06085.9 MGP_CAROLIEiJ_T0007267.1_32801102_3 - 0.038 13.6 0.6 0.083 12.5 0.6 1.6 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor DUF4106 PF13388.4 MGP_CAROLIEiJ_T0094539.1_32801110_1 - 0.002 17.3 7.9 0.0026 17.0 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) PT PF04886.10 MGP_CAROLIEiJ_T0094539.1_32801110_1 - 5.2 6.6 16.1 1.9 8.0 12.4 2.0 2 1 0 2 2 2 0 PT repeat PT PF04886.10 MGP_CAROLIEiJ_T0094539.1_32801110_2 - 9.9 5.7 18.0 9.6 5.7 12.4 2.7 2 1 0 2 2 2 0 PT repeat Prok-RING_1 PF14446.4 MGP_CAROLIEiJ_T0004489.1_32801104_2 - 0.025 14.4 2.6 0.025 14.4 2.6 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DUF4535 PF15054.4 MGP_PahariEiJ_T0006024.1_33003102_2 - 3.2e-17 61.8 0.2 5.5e-17 61.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) Abhydrolase_1 PF00561.18 MGP_PahariEiJ_T0005004.1_33003102_1 - 1.2e-15 57.7 0.0 2.4e-15 56.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 MGP_PahariEiJ_T0005004.1_33003102_1 - 6e-06 25.6 0.0 0.00017 20.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.7 MGP_PahariEiJ_T0005004.1_33003102_1 - 0.0036 16.8 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.5 MGP_PahariEiJ_T0005004.1_33003102_1 - 0.0071 16.9 0.0 0.0091 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.9 MGP_PahariEiJ_T0005004.1_33003102_1 - 0.022 14.5 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) FSH1 PF03959.11 MGP_PahariEiJ_T0005004.1_33003102_1 - 0.045 13.3 0.1 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF900 PF05990.10 MGP_PahariEiJ_T0005004.1_33003102_1 - 0.062 12.7 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydro_lipase PF04083.14 MGP_PahariEiJ_T0005004.1_33003102_3 - 4.4e-08 32.5 0.0 7.1e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region V-set_CD47 PF08204.9 MGP_PahariEiJ_T0005253.1_33003102_3 - 5.1e-47 159.0 0.4 7e-47 158.5 0.4 1.2 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain CD47 PF04549.12 MGP_PahariEiJ_T0005253.1_33003102_3 - 6.2e-26 91.2 13.7 1.2e-13 51.3 2.7 2.4 1 1 1 2 2 2 2 CD47 transmembrane region DUF2070 PF09843.7 MGP_PahariEiJ_T0005253.1_33003102_3 - 0.14 10.3 4.3 0.17 10.0 4.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-C2H2_6 PF13912.4 MGP_PahariEiJ_T0014125.1_33009114_2 - 3e-17 62.0 6.6 7.4e-07 28.8 0.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_4 PF13894.4 MGP_PahariEiJ_T0014125.1_33009114_2 - 2.4e-10 40.2 7.5 0.015 15.9 0.2 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger ELM2 PF01448.22 MGP_PahariEiJ_T0014125.1_33009114_2 - 2.4e-08 34.5 4.2 4.7e-07 30.3 0.0 2.9 2 0 0 2 2 2 1 ELM2 domain zf-C2H2 PF00096.24 MGP_PahariEiJ_T0014125.1_33009114_2 - 2.3e-07 30.8 15.5 0.034 14.5 1.2 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.5 MGP_PahariEiJ_T0014125.1_33009114_2 - 0.00011 22.3 1.0 0.035 14.3 0.0 2.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Myb_DNA-binding PF00249.29 MGP_PahariEiJ_T0014125.1_33009114_2 - 0.00073 19.5 0.1 0.0015 18.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-met PF12874.5 MGP_PahariEiJ_T0014125.1_33009114_2 - 0.019 15.2 6.0 0.15 12.4 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Sigma70_ner PF04546.11 MGP_PahariEiJ_T0014125.1_33009114_2 - 0.078 12.7 2.0 0.16 11.7 2.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Myb_DNA-bind_7 PF15963.3 MGP_PahariEiJ_T0014125.1_33009114_2 - 0.72 9.6 5.8 0.057 13.2 0.3 2.0 2 0 0 2 2 2 0 Myb DNA-binding like zf-C2H2_jaz PF12171.6 MGP_PahariEiJ_T0014125.1_33009114_2 - 1.6 9.0 10.4 1.6 9.0 0.7 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding SPATA19 PF15212.4 MGP_SPRETEiJ_T0006167.1_33102102_2 - 0.18 11.9 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial Cys_rich_CPXG PF14255.4 MGP_SPRETEiJ_T0016666.1_33102114_2 - 0.015 15.1 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG DUF1619 PF07773.9 MGP_SPRETEiJ_T0016983.1_33105114_2 - 1.1e-74 252.2 0.0 4.3e-71 240.3 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) MVL PF12151.6 ENSMPUT00000027772.1_33501102_2 - 0.19 11.5 1.4 0.28 11.0 1.4 1.3 1 0 0 1 1 1 0 Mannan-binding protein RCC1_2 PF13540.4 ENSMLUT00000025276.1_33801133_2 - 7 6.5 9.7 1.1 9.0 2.9 2.4 2 1 1 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat FMO-like PF00743.17 ENSMLUT00000030841.1_33801106_3 - 0.017 13.4 0.0 0.02 13.2 0.0 1.0 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like CCER1 PF15482.4 ENSMLUT00000022020.2_33801106_1 - 0.013 15.2 1.6 0.018 14.8 1.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 CAP_N PF01213.17 ENSMLUT00000019820.2_33801106_2 - 1.2 8.4 3.3 1.2 8.5 3.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal LBP_BPI_CETP PF01273.23 ENSNGAT00000032624.1_34004102_3 - 0.016 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Gemini_AC4_5 PF04807.10 ENSNLET00000025519.2_35701106_1 - 0.052 13.1 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Costars PF14705.4 ENSMEUT00000018338.1_35801106_2 - 0.06 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Costars Defensin_4 PF07936.10 ENSOPRT00000019745.1_36201106_2 - 0.0028 17.3 0.3 0.34 10.7 0.0 2.3 2 0 0 2 2 2 2 Potassium-channel blocking toxin TMEM108 PF15759.3 ENSODET00000029792.1_36301106_3 - 9 4.9 11.0 9.8 4.8 11.0 1.1 1 0 0 1 1 1 0 TMEM108 family Antimicrobial14 PF08109.9 ENSODET00000031848.1_36301106_2 - 0.094 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Lactocin 705 family DUF4964 PF16334.3 ENSONIT00000032986.1_37501102_1 - 0.054 12.9 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Syndecan PF01034.18 ENSONIT00000031432.1_37504102_2 - 0.086 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Ig_3 PF13927.4 ENSONIT00000029596.1_37503102_1 - 0.035 14.6 0.4 0.12 12.9 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.4 ENSONIT00000029596.1_37503102_2 - 1.6e-06 28.2 3.4 1e-05 25.6 0.5 2.5 1 1 1 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.4 ENSONIT00000029596.1_37503102_2 - 0.0068 16.9 1.6 0.13 12.8 0.6 2.7 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 ENSONIT00000029596.1_37503102_2 - 0.012 15.6 2.4 0.23 11.5 0.2 2.9 2 1 0 3 3 3 0 Immunoglobulin V-set domain KASH_CCD PF14662.4 ENSONIT00000032275.1_37501102_2 - 0.13 12.0 4.7 0.37 10.5 0.7 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Anoctamin PF04547.10 ENSOANT00000042572.1_37602102_1 - 0.0084 14.8 0.4 0.012 14.4 0.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Cadherin PF00028.15 ENSOANT00000043897.1_37601102_2 - 0.00018 21.7 0.5 0.0064 16.8 0.0 2.7 2 1 1 3 3 3 1 Cadherin domain DUF637 PF04830.11 ENSOANT00000045230.1_37602102_2 - 3.7 7.2 10.6 1.4 8.5 7.7 1.9 2 1 0 2 2 2 0 Possible hemagglutinin (DUF637) PMSI1 PF15322.4 ENSOANT00000044823.1_37603102_1 - 0.032 13.6 0.5 0.045 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Ion_trans PF00520.29 ENSOANT00000044790.1_37603102_3 - 1e-09 37.9 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ribosomal_60s PF00428.17 ENSOANT00000044790.1_37603102_3 - 0.2 12.1 3.4 0.46 10.9 3.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Humanin PF15040.4 ENSORLT00000026732.1_39104123_1 - 0.00084 18.7 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Humanin family FlhE PF06366.11 ENSOGAT00000024402.1_39401106_2 - 0.054 13.3 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Flagellar protein FlhE Mu-like_Pro PF10123.7 ENSOGAT00000024402.1_39401106_3 - 0.18 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DUF3704 PF12488.6 ENSOART00000027346.1_39507102_2 - 0.0086 15.6 1.1 0.02 14.4 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3704) Sirohm_synth_C PF14823.4 ENSOART00000027346.1_39507102_2 - 0.23 11.0 1.1 1.1 8.8 0.3 2.4 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal Bromo_TP PF07524.11 ENSOART00000027389.1_39505102_3 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Nudix_N PF12535.6 ENSOART00000027503.1_39502102_1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal PP1_bind PF15276.4 ENSOART00000028145.1_39503102_3 - 0.062 13.5 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 binding TSP_1 PF00090.17 ENSPTRT00000113459.1_39702102_2 - 0.0028 17.7 4.3 0.0028 17.7 4.3 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain DUF1932 PF09130.9 ENSPTRT00000069169.2_39701106_1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) ATG16 PF08614.9 ENSPANT00000060354.1_40403102_3 - 0.00046 20.3 3.1 0.00062 19.9 3.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) betaPIX_CC PF16523.3 ENSPANT00000060354.1_40403102_3 - 0.0038 16.9 4.9 0.0058 16.3 4.2 1.6 1 1 1 2 2 2 1 betaPIX coiled coil DUF812 PF05667.9 ENSPANT00000060354.1_40403102_3 - 0.0061 15.4 4.3 0.0075 15.1 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Mnd1 PF03962.13 ENSPANT00000060354.1_40403102_3 - 0.017 14.9 8.3 0.024 14.4 8.3 1.1 1 0 0 1 1 1 0 Mnd1 family FPP PF05911.9 ENSPANT00000060354.1_40403102_3 - 0.018 13.2 8.2 0.023 12.8 8.2 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF3552 PF12072.6 ENSPANT00000060354.1_40403102_3 - 0.032 13.5 9.6 0.043 13.1 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Zein-binding PF04576.13 ENSPANT00000060354.1_40403102_3 - 0.032 14.4 4.0 0.051 13.7 4.0 1.3 1 0 0 1 1 1 0 Zein-binding Seryl_tRNA_N PF02403.20 ENSPANT00000060354.1_40403102_3 - 0.036 14.2 6.7 0.054 13.6 6.7 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cons_hypoth95 PF03602.13 ENSPANT00000060354.1_40403102_3 - 0.13 11.7 1.2 0.19 11.2 1.2 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 IncA PF04156.12 ENSPANT00000060354.1_40403102_3 - 0.28 10.8 5.7 0.39 10.3 5.7 1.1 1 0 0 1 1 1 0 IncA protein TolA_bind_tri PF16331.3 ENSPANT00000060354.1_40403102_3 - 0.3 11.0 7.1 0.48 10.4 7.1 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3450 PF11932.6 ENSPANT00000060354.1_40403102_3 - 0.32 10.1 8.0 0.45 9.6 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.10 ENSPANT00000060354.1_40403102_3 - 0.44 9.8 9.0 0.61 9.3 9.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.9 ENSPANT00000060354.1_40403102_3 - 1.3 9.2 4.6 2.2 8.5 4.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-RING_11 PF17123.3 ENSPANT00000059605.1_40402102_3 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger MMADHC PF10229.7 ENSPANT00000059910.1_40403102_1 - 0.17 11.4 0.1 8 5.9 0.0 2.0 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type D protein Humanin PF15040.4 ENSPSIT00000021774.1_41104123_1 - 0.00012 21.4 0.0 0.00025 20.3 0.0 1.5 1 0 0 1 1 1 1 Humanin family Flavi_NS1 PF00948.19 ENSPSIT00000022502.1_41101133_1 - 0.33 9.6 2.8 0.36 9.5 2.8 1.0 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Humanin PF15040.4 ENSPMAT00000014110.1_41404123_3 - 2e-07 30.2 0.0 3.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Humanin family SR-25 PF10500.7 ENSPFOT00000021620.1_42701122_1 - 8.4 5.8 17.8 9.7 5.6 17.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein 7kD_coat PF02495.15 ENSPFOT00000021620.1_42701122_3 - 0.55 9.8 3.3 6.9 6.3 1.1 2.1 2 0 0 2 2 2 0 7kD viral coat protein DUF3915 PF13054.4 ENSPFOT00000021204.1_42701106_1 - 0.0064 16.3 2.7 0.0092 15.8 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) DUF2040 PF09745.7 ENSPFOT00000021204.1_42701106_1 - 0.1 12.5 3.4 0.13 12.2 3.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) Atrophin-1 PF03154.13 ENSPFOT00000021204.1_42701106_1 - 0.25 9.5 5.5 0.29 9.3 5.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family BES1_N PF05687.11 ENSPFOT00000021204.1_42701106_1 - 3.9 7.7 7.2 5.9 7.1 7.2 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal DUF3915 PF13054.4 ENSPFOT00000021204.1_42701106_2 - 0.58 10.0 7.2 0.79 9.6 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 ENSPFOT00000021204.1_42701106_2 - 3.8 5.5 10.7 4.4 5.3 10.7 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 ENSPFOT00000021204.1_42701106_3 - 2.5 7.9 6.9 3.1 7.7 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF1143 PF06608.9 ENSPPYT00000031964.1_43501133_1 - 0.041 13.8 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) zf-Paramyx-P PF13008.5 ENSPPYT00000031749.1_43501106_3 - 0.071 12.5 4.7 0.24 10.8 1.7 2.2 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein Humanin PF15040.4 ENSPCAT00000020673.1_43904123_2 - 3.4e-07 29.5 0.0 6.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Humanin family Sedlin_N PF04628.11 ENSPCAT00000019656.1_43901106_1 - 0.17 11.9 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region DUF35_N PF12172.6 ENSPVAT00000029302.1_44901106_3 - 0.058 13.1 0.5 0.097 12.4 0.5 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3885 PF13021.4 ENSPVAT00000027192.1_44901106_1 - 0.1 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) APC_r PF05923.10 ENSPVAT00000029541.1_44901106_3 - 0.27 10.9 7.3 0.84 9.3 4.4 2.1 2 0 0 2 2 2 0 APC repeat KASH PF10541.7 ENSRNOT00000091689.1_45701122_3 - 0.094 12.8 4.6 0.18 12.0 4.6 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain ArgoL1 PF08699.8 ENSRNOT00000085289.1_45703102_2 - 6.1e-24 83.3 0.1 1.1e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.3 ENSRNOT00000085289.1_45703102_2 - 0.00018 22.1 0.0 0.00032 21.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.20 ENSRNOT00000085289.1_45703102_2 - 0.034 13.8 0.1 0.05 13.3 0.1 1.3 1 0 0 1 1 1 0 PAZ domain Sirohm_synth_M PF14824.4 ENSRNOT00000082767.1_45702102_1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central SPX PF03105.17 ENSRNOT00000091754.1_45702102_1 - 0.19 11.5 0.0 0.21 11.3 0.0 1.0 1 0 0 1 1 1 0 SPX domain ADIP PF11559.6 ENSRNOT00000085930.1_45709102_1 - 1.1e-16 61.1 0.4 1.6e-16 60.6 0.4 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ADIP PF11559.6 ENSRNOT00000085930.1_45709102_2 - 6.6e-05 22.9 2.6 9.9e-05 22.3 2.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Herpes_BLLF1 PF05109.11 ENSRNOT00000085930.1_45709102_2 - 0.35 8.7 9.3 0.51 8.1 9.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Myosin_head PF00063.19 ENSRNOT00000087479.1_45702102_1 - 6.9e-09 34.3 0.0 8.9e-09 34.0 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) HnRNPA1 PF11627.6 ENSRNOT00000088540.1_45702102_2 - 1.8e-16 59.8 25.2 1.8e-16 59.8 25.2 4.3 3 1 0 3 3 3 1 Nuclear factor hnRNPA1 EGF_3 PF12947.5 ENSRNOT00000085734.1_45702102_2 - 0.037 14.1 0.5 0.07 13.2 0.5 1.4 1 0 0 1 1 1 0 EGF domain Plasmod_MYXSPDY PF07981.9 ENSRBIT00000069534.1_46102102_2 - 0.26 11.3 2.1 0.48 10.4 2.1 1.4 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY 7TM_GPCR_Srx PF10328.7 ENSRBIT00000069692.1_46101102_1 - 0.029 13.5 0.1 0.035 13.3 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx BPS PF08947.8 ENSRBIT00000070097.1_46102102_2 - 0.93 9.2 2.8 0.5 10.1 0.3 1.8 2 0 0 2 2 2 0 BPS (Between PH and SH2) TPR_7 PF13176.4 ENSRROT00000070571.1_46203102_1 - 0.00016 21.3 7.9 0.23 11.5 0.1 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.4 ENSRROT00000070571.1_46203102_1 - 0.013 15.7 9.4 0.52 10.5 0.2 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.15 ENSRROT00000070571.1_46203102_1 - 0.028 14.4 0.1 0.028 14.4 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.4 ENSRROT00000070571.1_46203102_1 - 0.084 13.0 9.2 0.45 10.7 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.4 ENSRROT00000070571.1_46203102_1 - 0.099 11.9 0.2 4 6.7 0.2 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.4 ENSRROT00000070571.1_46203102_1 - 0.12 12.2 2.7 26 4.8 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat C8 PF08742.9 ENSSBOT00000058283.1_46804102_2 - 0.002 18.4 0.3 0.0059 16.9 0.3 1.8 1 0 0 1 1 1 1 C8 domain VWD PF00094.23 ENSSBOT00000058283.1_46804102_2 - 0.15 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type D domain ORC2 PF04084.12 ENSSBOT00000058222.1_46802102_1 - 0.0027 16.6 2.6 0.0035 16.2 2.6 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 CoxIIa PF08113.9 ENSSBOT00000000182.1_46801106_1 - 0.18 11.5 0.8 0.3 10.8 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Gemini_AC4_5 PF04807.10 ENSSBOT00000014079.1_46801106_2 - 0.1 12.2 0.7 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region Tox-GHH PF15636.4 ENSSHAT00000023683.1_47101106_2 - 0.042 13.6 0.7 0.062 13.1 0.7 1.2 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF2805 PF10985.6 ENSSART00000019821.1_48801106_1 - 0.094 13.0 0.3 0.12 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) DUF782 PF05614.9 ENSSSCT00000037412.1_49805102_3 - 0.11 12.8 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) zf-C2H2_jaz PF12171.6 ENSSSCT00000055418.1_49808102_1 - 0.018 15.2 0.2 0.038 14.2 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 ENSSSCT00000055418.1_49808102_1 - 0.064 13.5 0.8 0.16 12.2 0.8 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.24 ENSSSCT00000055418.1_49808102_1 - 0.16 12.4 0.8 0.41 11.1 0.8 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.5 ENSSSCT00000055418.1_49808102_2 - 1.3e-07 31.7 11.7 0.0057 16.8 0.3 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.4 ENSSSCT00000055418.1_49808102_2 - 3.3e-06 27.3 7.9 0.058 14.1 0.1 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.24 ENSSSCT00000055418.1_49808102_2 - 0.0074 16.6 12.8 0.44 11.0 0.1 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.8 ENSSSCT00000055418.1_49808102_2 - 0.39 10.7 4.4 64 3.7 0.0 4.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_6 PF13912.4 ENSSSCT00000055418.1_49808102_2 - 1.8 8.5 17.8 1 9.2 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Humanin PF15040.4 ENSTGUT00000019451.1_49904123_1 - 6.4e-06 25.4 0.0 1.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Humanin family AA_permease_C PF13906.4 ENSTGUT00000019327.1_49901133_3 - 0.28 11.1 1.2 0.49 10.4 1.2 1.3 1 0 0 1 1 1 0 C-terminus of AA_permease TMEM191C PF15194.4 ENSTGUT00000018620.1_49901133_2 - 0.011 15.7 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 0 TMEM191C family Humanin PF15040.4 ENSTRUT00000048542.1_50004123_1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Humanin family Nbas_N PF15492.4 ENSTRUT00000048788.1_50001106_3 - 0.093 11.9 0.7 0.3 10.2 0.7 1.8 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Humanin PF15040.4 ENSTNIT00000003034.1_50504123_1 - 1.5e-07 30.6 0.0 2.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Humanin family ASD1 PF08688.8 ENSTNIT00000024009.1_50501133_1 - 0.15 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 PHD20L1_u1 PF16660.3 ENSTNIT00000023996.1_50501106_3 - 0.0088 16.6 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 1 PHD finger protein 20-like protein 1 Humanin PF15040.4 ENSTBET00000021317.1_52004123_3 - 1.1e-15 56.6 0.1 1.9e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Humanin family Inhibitor_Mig-6 PF11555.6 ENSTBET00000020332.1_52001106_1 - 0.17 11.9 1.9 0.25 11.3 1.9 1.3 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 SNARE PF05739.17 ENSTTRT00000023575.1_52201133_3 - 0.2 11.5 0.5 0.25 11.2 0.5 1.1 1 0 0 1 1 1 0 SNARE domain DUF1357 PF07094.9 ENSTTRT00000024261.1_52201133_2 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Myotoxins PF00819.15 ENSTTRT00000024838.1_52201106_1 - 0.0094 16.1 0.2 0.014 15.5 0.2 1.3 1 0 0 1 1 1 1 Myotoxin, crotamine Humanin PF15040.4 ENSXETT00000066484.1_53504123_3 - 0.084 12.3 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Humanin family Humanin PF15040.4 ENSXMAT00000020859.1_53604123_3 - 3.2e-06 26.4 0.0 7.5e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Humanin family Ras PF00071.20 NONATHT000133.1_03711102_3 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Ras family zf-BED PF02892.13 NONATHT000135.1_03713102_1 - 0.00057 19.7 5.2 0.0021 17.9 5.2 1.9 1 1 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.12 NONATHT000135.1_03713102_2 - 8e-21 73.5 0.7 1.3e-20 72.8 0.7 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Dimer_Tnp_hAT PF05699.12 NONATHT000135.1_03713102_3 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region HTH_27 PF13463.4 NONATHT000145.1_03711102_3 - 0.13 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Transpos_assoc PF13963.4 NONATHT001168.1_03712102_3 - 1.6e-13 50.8 0.1 2.4e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Transposase-associated domain rve PF00665.24 NONATHT002068.1_03716102_1 - 2.3e-09 37.4 0.1 3.5e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DUF223 PF02721.12 NONATHT002081.1_03715102_1 - 2.8e-16 59.5 0.1 5.4e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF223 Rep_fac-A_C PF08646.8 NONATHT002081.1_03715102_1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.3 NONATHT002081.1_03715102_3 - 0.06 13.1 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Replication protein A OB domain EGF_3 PF12947.5 NONATHT002621.1_03715102_3 - 0.002 18.1 0.1 0.0057 16.7 0.1 1.8 1 0 0 1 1 1 1 EGF domain cEGF PF12662.5 NONATHT002621.1_03715102_3 - 0.0024 17.6 0.2 0.0074 16.1 0.2 1.8 1 0 0 1 1 1 1 Complement Clr-like EGF-like TRAM1 PF08390.9 NONATHT002621.1_03715102_3 - 0.047 13.2 1.5 0.096 12.2 1.5 1.4 1 0 0 1 1 1 0 TRAM1-like protein EGF PF00008.25 NONATHT002621.1_03715102_3 - 0.22 11.8 0.2 0.22 11.8 0.2 2.9 4 0 0 4 4 4 0 EGF-like domain DUF223 PF02721.12 NONATHT002703.1_03711102_1 - 4.7e-22 78.0 0.3 6.8e-22 77.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF223 DUF4913 PF16259.3 NONATHT003650.1_03711102_1 - 0.0076 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4913) RVT_3 PF13456.4 NONATHT003650.1_03711102_1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like tRNA-synt_1e PF01406.17 NONCELT000140.2_07614117_2 - 3.2e-26 92.2 0.0 3.8e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.9 NONCELT000140.2_07614117_2 - 0.054 12.1 0.0 0.082 11.5 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) Lectin_C PF00059.19 NONCELT001164.2_07612102_2 - 3.1e-06 27.8 1.9 3.1e-06 27.8 1.9 2.2 2 1 1 3 3 3 1 Lectin C-type domain CUB PF00431.18 NONCELT001164.2_07612102_3 - 6.4e-23 81.1 0.3 1.4e-22 80.0 0.3 1.5 2 0 0 2 2 2 1 CUB domain VOMI PF03762.15 NONCELT003081.2_07611102_1 - 3.5e-18 66.2 0.1 4.1e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) HTH_24 PF13412.4 NONCELT004757.2_07613117_1 - 0.052 13.0 0.2 0.1 12.0 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Transposase_1 PF01359.16 NONCELT004757.2_07613117_2 - 4.5e-06 26.3 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.4 NONCELT004757.2_07613117_2 - 0.001 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease 7TM_GPCR_Srz PF10325.7 NONCELT007689.2_07612102_1 - 3.4e-30 105.2 44.1 1.2e-20 73.8 13.7 3.0 1 1 2 3 3 3 3 Serpentine type 7TM GPCR chemoreceptor Srz Gaa1 PF04114.12 NONCELT007689.2_07612102_1 - 0.93 8.3 12.4 1.2 8.0 12.4 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component 7TM_GPCR_Srt PF10321.7 NONCELT011871.2_07614102_1 - 6.5e-41 140.1 10.0 2.6e-20 72.5 0.4 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srt PF10321.7 NONCELT011871.2_07614102_2 - 3.3e-09 36.0 6.5 5.4e-09 35.3 6.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srt PF10321.7 NONCELT011871.2_07614102_3 - 1.8e-23 82.9 20.2 2.6e-23 82.3 3.8 2.6 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srh PF10318.7 NONCELT017924.2_07612118_1 - 2e-96 322.5 18.5 2.3e-96 322.3 18.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.7 NONCELT017924.2_07612118_1 - 2.4e-18 66.2 19.9 4.5e-18 65.3 19.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Str PF10326.7 NONCELT017924.2_07612118_1 - 1.1e-12 47.8 19.1 5.8e-12 45.5 10.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srd PF10317.7 NONCELT017924.2_07612118_1 - 4.9e-09 35.7 22.6 1.9e-08 33.7 22.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srj PF10319.7 NONCELT017924.2_07612118_1 - 1.1e-06 28.1 4.4 1.1e-06 28.1 4.4 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srj 7tm_1 PF00001.19 NONCELT017924.2_07612118_1 - 0.002 17.3 6.1 0.0036 16.5 6.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) YukC PF10140.7 NONCELT017924.2_07612118_1 - 0.025 13.3 4.7 0.038 12.7 0.6 2.4 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukC DUF4131 PF13567.4 NONCELT017924.2_07612118_1 - 1.5 8.3 8.9 0.79 9.2 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3671 PF12420.6 NONCELT017924.2_07612118_1 - 6.5 6.7 12.5 2.5 8.1 1.3 3.4 2 1 1 3 3 3 0 Protein of unknown function DUF996 PF06195.11 NONCELT017924.2_07612118_1 - 8.8 6.5 17.3 0.32 11.1 0.8 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF996) Cation_ATPase_C PF00689.19 NONCELT017924.2_07612118_1 - 9.5 5.7 13.9 8.3 5.9 10.3 2.5 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus 7TM_GPCR_Srbc PF10316.7 NONCELT019434.2_07611118_1 - 7.1e-13 48.5 0.7 9.7e-13 48.1 0.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srbc PF10316.7 NONCELT019434.2_07611118_2 - 1.2e-11 44.6 0.8 1.7e-11 44.0 0.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srz PF10325.7 NONCELT020611.2_07613102_1 - 4.3e-61 206.4 55.9 5.9e-61 206.0 55.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srz Holin_SPP1 PF04688.11 NONCELT020611.2_07613102_1 - 0.021 14.9 0.6 0.021 14.9 0.6 2.4 2 0 0 2 2 2 0 SPP1 phage holin Calpain_III PF01067.20 NONCELT024346.1_07615118_2 - 2.3e-24 86.1 0.0 4.5e-23 82.0 0.0 2.3 2 0 0 2 2 2 1 Calpain large subunit, domain III Peptidase_C2 PF00648.19 NONCELT024346.1_07615118_3 - 6.7e-101 337.1 0.2 8.2e-101 336.8 0.2 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease TIMELESS PF04821.12 NONGGAT006637.2_23517104_1 - 0.11 11.6 1.2 0.18 10.9 0.8 1.4 2 0 0 2 2 2 0 Timeless protein Lem_TRP PF08262.9 NONGGAT011489.2_23511102_3 - 7.9 6.6 7.1 30 4.8 0.9 2.8 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide RRXRR PF14239.4 NONPTRT000865.1_39712102_1 - 3.9 7.2 5.8 5.9 6.6 5.8 1.2 1 0 0 1 1 1 0 RRXRR protein rve PF00665.24 NONPTRT003599.1_39711102_1 - 0.025 14.7 0.1 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain TSNAXIP1_N PF15739.3 NONPTRT006091.1_39711102_2 - 9.3e-07 29.1 2.1 9.3e-07 29.1 2.1 1.9 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus Fer4_6 PF12837.5 NONPTRT013847.1_39712102_1 - 1.2 9.2 5.2 0.46 10.5 0.7 2.6 3 0 0 3 3 3 0 4Fe-4S binding domain Mnd1 PF03962.13 NONPTRT015994.1_39711118_1 - 0.0011 18.8 3.6 0.0011 18.8 3.6 1.0 1 0 0 1 1 1 1 Mnd1 family JIP_LZII PF16471.3 NONPTRT015994.1_39711118_1 - 0.0016 18.4 1.4 0.0036 17.3 0.6 1.8 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II GrpE PF01025.17 NONPTRT015994.1_39711118_1 - 0.0018 17.8 0.3 0.002 17.7 0.3 1.1 1 0 0 1 1 1 1 GrpE Apolipoprotein PF01442.16 NONPTRT015994.1_39711118_1 - 0.0083 15.9 1.5 0.012 15.4 1.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain FNIP_C PF14638.4 NONPTRT015994.1_39711118_1 - 0.02 14.4 0.3 0.021 14.3 0.3 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus NuDC PF16273.3 NONPTRT015994.1_39711118_1 - 0.025 15.0 3.3 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Nuclear distribution C domain ZapB PF06005.10 NONPTRT015994.1_39711118_1 - 0.037 14.3 7.3 2.3 8.6 7.3 2.6 1 1 0 1 1 1 0 Cell division protein ZapB DUF4795 PF16043.3 NONPTRT015994.1_39711118_1 - 0.039 13.4 2.0 0.042 13.3 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Spc7 PF08317.9 NONPTRT015994.1_39711118_1 - 0.047 12.4 3.0 0.059 12.1 3.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FAD_binding_7 PF03441.12 NONPTRT015994.1_39711118_1 - 0.086 12.2 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase CLZ PF16526.3 NONPTRT015994.1_39711118_1 - 0.16 12.2 5.6 0.91 9.8 0.8 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.9 NONPTRT015994.1_39711118_1 - 0.44 10.8 3.7 5.1 7.4 1.2 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ScdA_N PF04405.12 NONBTAT028030.1_06512102_1 - 0.15 11.6 2.1 0.27 10.8 2.1 1.3 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) DUF4535 PF15054.4 NONDMET024274.1_18511118_1 - 7.7e-18 63.8 0.9 1.5e-17 62.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4535) INCENP_N PF12178.6 NONDMET024274.1_18511118_1 - 0.21 11.4 0.3 0.35 10.7 0.3 1.3 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal RIIa PF02197.15 NONDMET027657.1_18517118_3 - 0.049 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit CK1gamma_C PF12605.6 NONDMET031994.1_18519118_1 - 8.8e-17 62.0 1.2 4.6e-09 37.2 0.3 2.6 2 0 0 2 2 2 2 Casein kinase 1 gamma C terminal CK1gamma_C PF12605.6 NONDMET031994.1_18519118_3 - 0.00096 20.1 0.3 0.00096 20.1 0.3 1.9 2 0 0 2 2 2 1 Casein kinase 1 gamma C terminal DUF1265 PF06887.12 NONDMET038653.1_18512102_2 - 0.11 12.3 0.3 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) E1-E2_ATPase PF00122.18 NONDMET044126.1_18514118_1 - 5.3e-07 29.0 0.0 7.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.6 NONDMET044126.1_18514118_1 - 0.0015 18.5 0.2 0.003 17.5 0.2 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter P5-ATPase PF12409.6 NONDMET044126.1_18514118_2 - 0.00029 20.8 1.1 0.00029 20.8 1.1 1.7 2 0 0 2 2 2 1 P5-type ATPase cation transporter Utp21 PF04192.10 NONGGOT002395.1_24212102_3 - 1.3e-06 28.0 0.8 23 4.2 0.0 6.2 4 1 5 9 9 9 6 Utp21 specific WD40 associated putative domain MRP-S31 PF15433.4 NONGGOT005369.1_24212102_1 - 0.059 12.9 0.1 0.082 12.5 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 MRP-S31 PF15433.4 NONGGOT005369.1_24212102_3 - 0.00015 21.5 1.3 0.13 11.8 0.1 2.1 1 1 0 2 2 2 2 Mitochondrial 28S ribosomal protein S31 UPF0561 PF10573.7 NONGGOT011508.1_24219102_2 - 6.5e-14 52.0 0.1 1e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0561 LINES_C PF14695.4 NONHSAT029709.2_26212102_3 - 0.015 14.6 0.2 0.029 13.7 0.2 1.4 1 0 0 1 1 1 0 Lines C-terminus Ribosomal_S10 PF00338.20 NONHSAT031963.2_26211102_3 - 4.9e-07 29.7 0.0 6.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e p450 PF00067.20 NONHSAT116781.2_26212102_3 - 6.4e-06 25.0 0.0 6.8e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NTase_sub_bind PF08780.9 NONHSAT127734.2_26211102_2 - 0.042 13.7 0.1 0.05 13.4 0.1 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like dsrm PF00035.24 NONHSAT139917.2_26211118_2 - 0.0064 17.0 0.1 0.0087 16.6 0.1 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif E_raikovi_mat PF06360.9 NONHSAT161048.1_26215102_2 - 0.79 10.1 0.0 0.79 10.1 0.0 3.8 4 0 0 4 4 4 0 Euplotes raikovi mating pheromone Yae1_N PF09811.7 NONMMUT095382.1_32912102_1 - 0.27 10.8 1.7 0.41 10.3 1.7 1.2 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.7 NONMMUT095382.1_32912102_2 - 0.05 13.2 2.5 0.076 12.6 2.5 1.2 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.7 NONMMUT095382.1_32912102_3 - 0.33 10.6 2.5 0.52 9.9 2.5 1.2 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Atrophin-1 PF03154.13 NONMMUT095382.1_32912102_3 - 4.1 5.4 16.3 5.1 5.1 16.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family TLV_coat PF00429.17 NONMMUT118979.1_32913102_2 - 2e-38 132.3 0.3 8.4e-23 80.7 0.0 2.1 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) PHD_2 PF13831.4 NONMMUT138847.1_32911102_2 - 0.03 13.7 0.4 0.088 12.2 0.4 1.7 1 0 0 1 1 1 0 PHD-finger KRAB PF01352.25 NONPPYT006505.1_43512102_1 - 2e-05 24.0 0.4 5.1e-05 22.7 0.4 1.7 1 1 0 1 1 1 1 KRAB box SHNi-TPR PF10516.7 NONPPYT006505.1_43512102_1 - 0.062 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 SHNi-TPR VWA PF00092.26 NONPPYT009292.1_43511102_3 - 3.9e-08 33.6 0.0 4e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain MMTV_SAg PF01054.15 NONPPYT010839.1_43511118_1 - 0.013 14.6 0.0 0.015 14.3 0.0 1.0 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen ENOD40 PF08247.9 NONSUST006717.1_49812102_3 - 0.24 11.3 2.2 0.52 10.3 2.2 1.5 1 0 0 1 1 1 0 ENOD40 protein T2SSB PF16537.3 NONSUST022484.1_49813102_2 - 0.074 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system protein B DUF3704 PF12488.6 NONSUST028339.1_49818102_1 - 0.015 14.8 1.0 0.034 13.7 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) DUF1416 PF07210.10 NONOANT002207.1_37612102_2 - 0.22 11.3 1.6 7.2 6.4 0.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1416) Pericardin_rpt PF07054.9 NONOANT002207.1_37612102_3 - 0.15 12.1 2.1 15 5.7 0.7 3.0 1 1 2 3 3 3 0 Pericardin like repeat Tai4 PF16695.3 NONOANT007380.1_37611102_2 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 1 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein Urotensin_II PF02083.13 NONOANT007528.1_37611102_3 - 2.5e-05 23.5 1.3 6.9e-05 22.2 1.3 1.8 1 0 0 1 1 1 1 Urotensin II AMA-1 PF02430.13 NONOANT009132.1_37611102_3 - 0.048 12.5 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Baculo_LEF-11 PF06385.10 NONRATT002231.2_45714102_1 - 1.4 9.4 8.3 1.8 9.0 1.5 3.6 3 2 1 4 4 4 0 Baculovirus LEF-11 protein zf-C2H2 PF00096.24 NONRATT002231.2_45714102_2 - 0.0096 16.2 1.5 0.0096 16.2 1.5 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONRATT002231.2_45714102_2 - 0.016 15.8 0.8 0.05 14.3 0.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.4 NONRATT002231.2_45714102_2 - 0.034 14.0 0.6 0.069 13.0 0.6 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.4 NONRATT002231.2_45714102_2 - 0.066 13.6 4.7 0.81 10.1 1.3 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-H2C2_2 PF13465.4 NONRATT002231.2_45714102_3 - 4.2e-25 86.9 45.3 2.9e-08 33.6 1.1 8.0 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.24 NONRATT002231.2_45714102_3 - 2.3e-17 62.3 42.7 4.5e-06 26.7 1.3 7.9 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONRATT002231.2_45714102_3 - 6.3e-05 23.3 42.1 0.01 16.4 1.0 7.2 7 0 0 7 7 7 3 C2H2-type zinc finger OB_NTP_bind PF07717.14 NONRATT003283.2_45713118_1 - 7.8e-07 29.1 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold TERF2_RBM PF16772.3 NONRATT005180.2_45713102_3 - 0.18 11.1 0.3 0.35 10.2 0.3 1.4 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif CAP_C PF08603.9 NONRATT012360.2_45712118_1 - 0.0071 15.8 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Noc2 PF03715.11 NONRATT022967.2_45711118_3 - 4.4e-23 81.9 0.0 5.2e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Noc2p family Arfaptin PF06456.11 NONRATT026111.2_45712118_2 - 1.6e-06 27.7 0.0 2.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Arfaptin-like domain PPAK PF02818.13 NONMMLT001999.1_29611102_2 - 0.00018 21.4 13.8 0.00018 21.4 13.8 4.7 5 1 0 5 5 5 3 PPAK motif DUF4245 PF14030.4 NONMMLT001999.1_29611102_2 - 0.13 12.1 0.1 0.19 11.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4245) EspG PF06872.9 NONMMLT002723.1_29611102_1 - 0.027 12.9 0.0 0.033 12.6 0.0 1.0 1 0 0 1 1 1 0 EspG protein DUF1725 PF08333.9 NONMMLT004296.1_29613102_2 - 0.017 14.6 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) DUF3719 PF12516.6 NONMMLT007792.1_29614102_2 - 3.6e-16 58.5 2.5 2.3e-15 55.9 2.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3719) RNase_Zc3h12a PF11977.6 NONMMLT007830.1_29612102_2 - 0.0075 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PALP PF00291.23 NONSCET000081.2_46511102_1 - 6.3e-25 88.0 0.0 6.7e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme EGF PF00008.25 NONDRET006010.2_16112102_3 - 1.6 9.0 4.9 34 4.7 4.9 2.2 1 1 0 1 1 1 0 EGF-like domain Borrelia_orfX PF04160.10 NONDRET012894.1_16111102_2 - 0.089 12.7 4.2 2.5 8.0 0.6 2.1 1 1 0 2 2 2 0 Orf-X protein Keratin_B2_2 PF13885.4 NONDRET012894.1_16111102_2 - 0.15 11.9 15.6 1.6 8.7 4.0 2.5 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein zf-HC5HC2H PF13771.4 NONDRET014173.1_16111102_3 - 0.0063 16.6 1.2 0.009 16.1 1.2 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain Chitin_bind_4 PF00379.21 001173178.1_06221001_1 - 8e-11 42.2 3.1 8e-11 42.2 3.1 1.9 2 0 0 2 2 2 1 Insect cuticle protein DUF2946 PF11162.6 001173178.1_06221001_1 - 0.15 12.6 7.0 0.29 11.7 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) zf-B_box PF00643.22 001173178.1_06221001_3 - 0.013 15.5 4.9 0.019 15.0 4.9 1.2 1 0 0 1 1 1 0 B-box zinc finger p450 PF00067.20 001083611.1_06224001_1 - 2.4e-95 319.9 0.0 2.9e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HypD PF01924.14 001083611.1_06224001_1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family DUF1521 PF07481.9 001083611.1_06224001_1 - 0.17 11.7 0.0 0.89 9.4 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1521) Keratin_assoc PF09775.7 001046731.1_06222001_3 - 9.9e-49 164.1 7.7 1.3e-48 163.8 7.7 1.1 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 Afaf PF15339.4 001046731.1_06222001_3 - 0.058 13.0 0.2 0.058 13.0 0.2 1.7 2 0 0 2 2 2 0 Acrosome formation-associated factor Transferrin PF00405.15 001304604.2_48726001_1 - 6.1e-76 255.6 0.5 1.6e-44 152.3 0.0 2.1 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.5 001304604.2_48726001_1 - 2.2e-10 40.4 0.0 0.00049 19.6 0.0 2.6 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.18 001304604.2_48726001_1 - 0.013 14.8 0.4 0.061 12.6 0.0 2.2 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 SNF PF00209.16 001011643.1_03125001_3 - 8.5e-219 727.4 38.0 1e-218 727.2 38.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Neuroparsin PF07327.9 001040269.1_03123001_2 - 3.3e-08 33.8 11.2 5.1e-08 33.2 11.2 1.2 1 0 0 1 1 1 1 Neuroparsin PBP_GOBP PF01395.20 001040223.1_03122001_2 - 2.5e-13 50.1 2.4 3.1e-13 49.8 2.4 1.1 1 0 0 1 1 1 1 PBP/GOBP family MRJP PF03022.14 001014429.1_03123001_2 - 4.2e-109 364.2 3.9 5.2e-109 363.9 3.9 1.1 1 0 0 1 1 1 1 Major royal jelly protein Acyl_transf_1 PF00698.19 001044013.1_06229001_1 - 1.2e-74 251.6 0.0 2e-74 250.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.24 001044013.1_06229001_1 - 3.8e-68 229.7 0.0 7.1e-68 228.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.8 001044013.1_06229001_1 - 1.4e-40 139.0 0.0 2.8e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.3 001044013.1_06229001_1 - 6.3e-32 110.2 0.0 1.6e-31 108.9 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.20 001044013.1_06229001_1 - 8.3e-32 109.6 0.0 1.6e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.24 001044013.1_06229001_1 - 6.3e-26 90.7 0.0 2e-25 89.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.4 001044013.1_06229001_1 - 5.4e-14 52.0 0.0 9.2e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.18 001044013.1_06229001_1 - 3.8e-13 50.0 0.0 1.2e-12 48.3 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain ADH_zinc_N_2 PF13602.4 001044013.1_06229001_1 - 7.3e-13 49.6 0.0 2.5e-12 47.8 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.23 001044013.1_06229001_1 - 6.8e-09 35.8 0.4 2.6e-07 30.7 0.5 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.23 001044013.1_06229001_1 - 1.9e-08 33.9 0.3 2e-06 27.2 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.21 001044013.1_06229001_1 - 8.5e-05 21.9 0.0 0.00028 20.2 0.0 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.4 001044013.1_06229001_1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.5 001044013.1_06229001_1 - 0.039 14.4 0.0 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family PMSR PF01625.19 001046899.2_06223001_3 - 3e-39 134.5 0.4 4.2e-39 134.0 0.4 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF2705 PF10920.6 001046899.2_06223001_3 - 0.0067 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2705) DUF1036 PF06282.9 001046899.2_06223001_3 - 0.04 14.3 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1036) MCM PF00493.21 001043453.1_06225001_1 - 4.3e-132 440.1 0.0 6.3e-132 439.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_OB PF17207.1 001043453.1_06225001_1 - 9.1e-28 96.5 0.3 2.2e-27 95.3 0.3 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.4 001043453.1_06225001_1 - 3.9e-18 65.8 4.1 1.1e-17 64.3 4.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.19 001043453.1_06225001_1 - 3.5e-08 33.0 0.0 7.9e-06 25.3 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.12 001043453.1_06225001_1 - 1.2e-06 28.4 0.0 3.4e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.24 001043453.1_06225001_1 - 0.0037 16.9 0.0 0.017 14.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.9 001043453.1_06225001_1 - 0.028 14.1 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.4 001043453.1_06225001_1 - 0.032 14.7 1.6 0.35 11.4 1.6 2.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Ribosomal_S13 PF00416.20 001043453.1_06225001_1 - 0.12 12.6 1.5 0.44 10.8 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S13/S18 2-Hacid_dh_C PF02826.17 001047075.1_06224001_3 - 1.4e-58 197.1 0.0 1.9e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.28 001047075.1_06224001_3 - 8.3e-30 103.1 0.0 1.1e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.13 001047075.1_06224001_3 - 0.00045 20.3 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.22 001047075.1_06224001_3 - 0.0037 17.5 0.1 0.0072 16.5 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.15 001047075.1_06224001_3 - 0.0051 17.2 0.0 0.15 12.6 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.18 001047075.1_06224001_3 - 0.0093 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.19 001047075.1_06224001_3 - 0.012 15.5 0.3 0.047 13.6 0.3 1.9 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.10 001047075.1_06224001_3 - 0.024 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.16 001047075.1_06224001_3 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.16 001047075.1_06224001_3 - 0.097 12.8 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain Linker_histone PF00538.17 001046782.1_06222001_2 - 8.1e-26 90.1 2.5 2.4e-25 88.5 2.5 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family MIP-T3 PF10243.7 001046782.1_06222001_2 - 0.0031 16.2 28.9 0.0031 16.2 28.9 1.4 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 DUF4777 PF16007.3 001046782.1_06222001_2 - 0.11 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Histone_H2A_C PF16211.3 001044181.1_06223001_1 - 0.69 9.6 4.9 1.2 8.8 4.9 1.4 1 0 0 1 1 1 0 C-terminus of histone H2A RRM_1 PF00076.20 001044181.1_06223001_2 - 1.7e-38 130.2 0.0 9e-19 66.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001044181.1_06223001_2 - 6.5e-07 29.2 0.1 0.0041 17.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.4 001044181.1_06223001_2 - 8.2e-06 25.3 0.0 0.0015 18.0 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.6 001044181.1_06223001_2 - 0.13 12.2 0.1 9.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 OB_RNB PF08206.9 001044181.1_06223001_2 - 0.15 11.7 0.2 0.84 9.2 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain EMP24_GP25L PF01105.22 001047045.1_06223001_2 - 3e-44 151.0 0.1 4.2e-44 150.5 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD OAD_gamma PF04277.11 001047045.1_06223001_2 - 0.21 12.0 3.9 0.54 10.7 3.9 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MIP PF00230.18 001043454.1_06225001_1 - 1e-61 208.4 14.9 1.3e-61 208.0 14.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Hormone_recep PF00104.28 001011634.2_03128001_1 - 1.6e-35 122.5 0.0 2.5e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001011634.2_03128001_1 - 1.3e-31 108.7 16.5 4.1e-31 107.1 16.5 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CBM39 PF15886.3 001135200.1_06224001_1 - 5e-26 90.8 0.0 1e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 32) Glyco_hydro_16 PF00722.19 001135200.1_06224001_1 - 3.2e-07 29.9 0.0 0.0001 21.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Peptidase_U32_C PF16325.3 001135200.1_06224001_1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain DUF2464 PF10240.7 001112672.2_03124001_2 - 8.5e-86 287.4 0.2 1.1e-85 287.0 0.2 1.1 1 0 0 1 1 1 1 Multivesicular body subunit 12 DUF1676 PF07898.11 001135889.1_06223001_3 - 4.1e-38 131.0 0.1 5.6e-38 130.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) Pkinase PF00069.23 001099833.1_06223001_1 - 3.5e-69 233.0 0.0 4.3e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001099833.1_06223001_1 - 1.1e-32 113.2 0.0 1.5e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001099833.1_06223001_1 - 9.5e-08 31.6 0.0 1.5e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Actin PF00022.17 001164951.1_46625001_1 - 1.5e-148 494.6 0.0 3.7e-148 493.3 0.0 1.5 1 1 0 1 1 1 1 Actin NADH_B2 PF14813.4 001163463.1_03121001_2 - 1.6e-24 85.3 5.6 2.3e-24 84.8 5.6 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 1-cysPrx_C PF10417.7 001163463.1_03121001_2 - 0.051 13.3 0.1 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Neur_chan_memb PF02932.14 001173346.1_06224001_2 - 8.2e-80 268.2 0.2 1.1e-79 267.8 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.21 001173346.1_06224001_2 - 2.6e-79 265.5 2.6 3.6e-79 265.1 2.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF4361 PF14274.4 001173346.1_06224001_2 - 0.1 12.7 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) Tetraspannin PF00335.18 001173346.1_06224001_2 - 0.3 10.7 4.1 0.2 11.4 1.0 2.2 3 0 0 3 3 3 0 Tetraspanin family DUF21 PF01595.18 001173346.1_06224001_2 - 2.2 7.8 6.8 4.2 6.9 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF21 7tm_6 PF02949.18 001242958.1_03124001_3 - 5e-28 98.0 22.2 9.1e-28 97.1 22.2 1.4 1 0 0 1 1 1 1 7tm Odorant receptor DNA_methylase PF00145.15 001171051.1_03129001_1 - 2.1e-53 181.7 0.8 1.7e-51 175.4 0.0 2.7 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.6 001171051.1_03129001_1 - 2.8e-39 134.3 0.0 7.3e-39 133.0 0.0 1.8 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.16 001171051.1_03129001_1 - 8.7e-25 86.8 9.2 1.8e-15 56.7 0.0 3.3 4 0 0 4 4 4 2 BAH domain zf-CXXC PF02008.18 001171051.1_03129001_1 - 1.2e-13 50.7 17.9 1.2e-13 50.7 17.9 3.0 3 0 0 3 3 3 1 CXXC zinc finger domain Pkinase_Tyr PF07714.15 001202530.1_06225001_1 - 4.4e-57 193.2 0.0 6.6e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001202530.1_06225001_1 - 5.9e-52 176.5 0.0 9.6e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.13 001202530.1_06225001_1 - 1.1e-22 79.8 0.2 2e-22 78.9 0.2 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.20 001202530.1_06225001_1 - 8.3e-08 31.9 13.6 8.3e-08 31.9 13.6 2.5 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.4 001202530.1_06225001_1 - 3e-05 23.4 0.0 5.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C1_2 PF03107.14 001202530.1_06225001_1 - 0.00024 21.2 10.2 0.00041 20.5 8.0 2.5 2 0 0 2 2 2 1 C1 domain zf-RING-like PF08746.9 001202530.1_06225001_1 - 0.027 14.6 10.0 0.15 12.3 10.0 2.3 1 0 0 1 1 1 0 RING-like domain APH PF01636.21 001202530.1_06225001_1 - 0.11 12.2 3.3 0.2 11.4 0.1 2.9 3 1 0 3 3 3 0 Phosphotransferase enzyme family PHD_2 PF13831.4 001202530.1_06225001_1 - 0.32 10.4 6.5 0.15 11.5 0.4 3.1 3 0 0 3 3 3 0 PHD-finger 7tm_6 PF02949.18 001242959.1_03123001_1 - 2e-25 89.4 19.9 2e-25 89.4 19.9 1.5 2 0 0 2 2 2 1 7tm Odorant receptor RecG_N PF17190.2 001242959.1_03123001_1 - 0.05 14.2 1.2 0.32 11.6 0.1 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF3377 PF11857.6 001242959.1_03123001_1 - 0.78 9.6 4.1 8.1 6.3 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EGF PF00008.25 001163899.1_06226001_1 - 3.2e-40 135.9 149.6 1.7e-07 31.3 7.4 11.7 11 1 0 11 11 11 8 EGF-like domain hEGF PF12661.5 001163899.1_06226001_1 - 6.3e-24 83.6 141.5 1.3e-06 28.7 5.4 12.2 13 0 0 13 13 13 9 Human growth factor-like EGF MNNL PF07657.11 001163899.1_06226001_1 - 3.5e-22 78.1 0.6 3.5e-22 78.1 0.6 4.4 5 0 0 5 5 5 1 N terminus of Notch ligand DSL PF01414.17 001163899.1_06226001_1 - 9.5e-22 76.8 3.8 9.5e-22 76.8 3.8 7.2 4 2 3 7 7 7 1 Delta serrate ligand EGF_2 PF07974.11 001163899.1_06226001_1 - 7.6e-13 48.4 172.3 0.0086 16.3 11.7 12.0 11 0 0 11 11 11 8 EGF-like domain EGF_CA PF07645.13 001163899.1_06226001_1 - 1.8e-08 34.3 121.0 4.8e-05 23.4 6.3 11.0 4 3 5 9 9 9 5 Calcium-binding EGF domain SIMPL PF04402.12 001163899.1_06226001_1 - 2.2 8.6 4.2 3.3 8.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) CSD PF00313.20 001204631.1_03224001_1 - 6.7e-27 93.0 0.9 1.1e-26 92.4 0.9 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.9 001204631.1_03224001_1 - 0.0065 16.0 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain UBA PF00627.29 001171181.1_06223001_1 - 8.9e-27 92.5 2.1 7.8e-13 47.9 0.3 2.4 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.9 001171181.1_06223001_1 - 5.9e-26 89.9 13.0 1.2e-25 88.8 13.0 1.6 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.21 001171181.1_06223001_1 - 2e-19 69.0 2.0 4.4e-19 67.9 2.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 001171181.1_06223001_1 - 1.6e-05 24.5 3.8 2.8e-05 23.7 3.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001171181.1_06223001_1 - 0.023 15.1 0.1 0.064 13.7 0.0 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.4 001171181.1_06223001_1 - 0.054 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1176 PF06674.9 001171181.1_06223001_1 - 2.6 7.3 5.3 0.59 9.4 0.9 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1176) Tat PF00539.16 001171181.1_06223001_2 - 1.2 9.3 10.7 2.4 8.2 10.7 1.5 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) 7tm_1 PF00001.19 001202460.1_03124001_1 - 6.9e-61 205.7 6.7 9.9e-61 205.2 6.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001202460.1_03124001_1 - 0.071 12.7 13.0 0.028 14.0 2.4 3.0 2 1 1 3 3 3 0 Olfactory receptor Ciart PF15673.3 001173294.1_06222001_3 - 0.97 8.7 6.9 0.062 12.6 0.8 1.8 1 1 0 2 2 2 0 Circadian-associated transcriptional repressor DUF3421 PF11901.6 001279393.1_10522001_2 - 1.5e-41 140.9 0.8 8.7e-40 135.2 0.5 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) CK_II_beta PF01214.16 001279368.1_10522001_1 - 1.8e-84 282.0 0.0 2.1e-84 281.8 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ald_Xan_dh_C2 PF02738.16 001279428.1_10529001_1 - 9e-202 671.2 0.0 1.2e-201 670.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001279428.1_10529001_1 - 1.6e-43 148.2 0.0 3e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001279428.1_10529001_1 - 9.3e-36 122.4 2.5 1e-35 122.3 1.0 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001279428.1_10529001_1 - 1.4e-29 102.1 0.2 2.4e-28 98.2 0.1 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.18 001279428.1_10529001_1 - 1.8e-29 101.4 0.1 5.5e-29 99.8 0.1 1.9 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.25 001279428.1_10529001_1 - 1.1e-07 31.6 3.4 2.8e-07 30.2 2.3 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DNA_binding_1 PF01035.18 001279428.1_10529001_1 - 0.018 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Chitin_bind_4 PF00379.21 001270818.1_03122001_1 - 1.6e-14 54.0 2.6 2.5e-14 53.4 2.6 1.4 1 0 0 1 1 1 1 Insect cuticle protein Homeobox PF00046.27 001279423.1_10528001_1 - 4.9e-21 74.2 1.4 1.1e-20 73.1 1.4 1.6 1 0 0 1 1 1 1 Homeobox domain zf-nanos PF05741.11 001279431.1_10525001_1 - 1.8e-22 79.2 3.4 1.8e-22 79.2 3.4 1.8 2 0 0 2 2 2 1 Nanos RNA binding domain HLH PF00010.24 001257008.1_06224001_2 - 3.2e-09 36.5 0.8 3.2e-09 36.5 0.8 2.4 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Myc_N PF01056.16 001257008.1_06224001_2 - 0.00035 20.4 0.3 0.42 10.3 0.3 2.2 2 0 0 2 2 2 2 Myc amino-terminal region ALF PF03752.11 001257008.1_06224001_3 - 0.19 11.6 2.7 0.32 10.9 2.7 1.3 1 0 0 1 1 1 0 Short repeats of unknown function Thiolase_N PF00108.21 001280933.1_06124001_1 - 8.8e-98 326.7 0.7 1.2e-97 326.2 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.16 001280933.1_06124001_1 - 1.3e-47 160.3 1.8 2.4e-47 159.5 1.8 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.24 001280933.1_06124001_1 - 0.052 13.0 1.4 0.1 12.0 0.1 2.0 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.8 001280933.1_06124001_1 - 0.11 12.6 0.2 0.26 11.4 0.2 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal p450 PF00067.20 001286880.1_33324001_3 - 4.5e-80 269.5 0.2 5.9e-80 269.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.19 001280911.1_06129001_1 - 6e-78 262.4 0.0 9.1e-78 261.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.24 001280911.1_06129001_1 - 4.6e-72 242.5 0.0 7.9e-72 241.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.8 001280911.1_06129001_1 - 4.8e-47 160.1 0.0 1.4e-46 158.6 0.0 1.8 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.20 001280911.1_06129001_1 - 1.4e-39 134.7 0.1 8.5e-39 132.1 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.3 001280911.1_06129001_1 - 1.5e-38 131.6 0.0 3.4e-38 130.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.18 001280911.1_06129001_1 - 3.4e-22 79.6 0.0 7.4e-22 78.5 0.0 1.6 2 0 0 2 2 1 1 Thioesterase domain ADH_zinc_N PF00107.24 001280911.1_06129001_1 - 3.5e-21 75.3 0.0 1.3e-20 73.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.4 001280911.1_06129001_1 - 2.1e-14 54.6 0.0 6.1e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.4 001280911.1_06129001_1 - 1e-12 47.8 0.0 2.5e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.23 001280911.1_06129001_1 - 9e-07 29.0 0.1 2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.21 001280911.1_06129001_1 - 2.8e-05 23.5 0.0 7.5e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.23 001280911.1_06129001_1 - 4.9e-05 22.7 0.4 0.00042 19.7 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Homeobox PF00046.27 001286907.1_33323001_1 - 7.8e-19 67.1 1.8 1.8e-18 66.0 1.8 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.6 001286907.1_33323001_1 - 0.035 13.4 0.0 0.035 13.4 0.0 2.0 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.9 001286907.1_33323001_1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.6 2 0 0 2 2 2 0 Homeobox KN domain RHD_DNA_bind PF00554.20 001279309.1_01728001_2 - 1.9e-60 203.5 0.1 3.4e-60 202.7 0.1 1.4 1 0 0 1 1 1 1 Rel homology DNA-binding domain Ank_2 PF12796.5 001279309.1_01728001_2 - 2.4e-41 140.0 10.1 5.5e-15 55.6 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) RHD_dimer PF16179.3 001279309.1_01728001_2 - 1.4e-36 124.5 0.0 2.5e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_4 PF13637.4 001279309.1_01728001_2 - 2.4e-28 98.0 3.1 2e-06 28.1 0.0 5.9 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.28 001279309.1_01728001_2 - 2e-24 84.8 11.4 2.5e-06 27.6 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.4 001279309.1_01728001_2 - 4.4e-24 84.0 9.3 1.7e-07 31.3 0.1 5.5 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.4 001279309.1_01728001_2 - 5.5e-22 75.3 5.1 0.00054 20.1 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Death PF00531.20 001279309.1_01728001_2 - 6.7e-08 32.5 0.2 1.7e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 Death domain Peptidase_M1 PF01433.18 001267725.1_06226001_1 - 1.1e-73 248.7 1.0 1.7e-59 201.9 2.8 2.3 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.6 001267725.1_06226001_1 - 1.3e-56 192.3 5.5 2.5e-56 191.4 5.5 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DDE_Tnp_1_7 PF13843.4 001267725.1_06226001_1 - 0.00017 20.9 0.0 0.00029 20.1 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 RhoGAP PF00620.25 001267725.1_06226001_1 - 0.0059 16.3 0.2 0.026 14.2 0.2 1.9 1 1 0 1 1 1 1 RhoGAP domain DUF1360 PF07098.9 001267725.1_06226001_1 - 0.037 13.8 0.8 0.087 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Peptidase_M1 PF01433.18 001287842.1_06226001_2 - 1.3e-119 399.9 2.3 1.6e-119 399.6 1.2 1.7 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.6 001287842.1_06226001_2 - 6.9e-72 242.5 4.5 1.1e-71 241.9 4.5 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Serendipity_A PF05482.10 001279396.1_10526001_2 - 1.3e-106 357.3 18.7 2.3e-106 356.5 18.7 1.3 1 0 0 1 1 1 1 Serendipity locus alpha protein (SRY-A) Herpes_UL33 PF03581.11 001279396.1_10526001_2 - 0.04 14.1 0.2 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus UL33-like protein Hrs_helical PF12210.6 001279396.1_10526001_2 - 0.1 13.0 3.8 0.59 10.6 0.1 3.4 3 1 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate PBP_GOBP PF01395.20 001312664.1_01922001_3 - 4.2e-15 55.8 2.0 5.9e-15 55.3 2.0 1.2 1 0 0 1 1 1 1 PBP/GOBP family Metallophos PF00149.26 001309140.1_42627001_1 - 5.9e-36 124.8 0.0 9.1e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thiolase_N PF00108.21 001311727.1_40224001_1 - 1.5e-83 280.0 0.1 2.4e-83 279.4 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.16 001311727.1_40224001_1 - 7.3e-48 161.2 0.9 2.4e-47 159.5 0.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.24 001311727.1_40224001_1 - 0.012 15.0 3.4 0.38 10.1 0.0 3.5 4 0 0 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain DEAD PF00270.27 001315586.1_13526001_1 - 3.5e-49 166.8 0.0 7.3e-49 165.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001315586.1_13526001_1 - 2.2e-29 101.9 0.1 2.4e-28 98.6 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001315586.1_13526001_1 - 0.00013 21.9 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GRP PF07172.9 001315586.1_13526001_3 - 0.61 10.7 25.7 0.92 10.1 25.7 1.2 1 0 0 1 1 1 0 Glycine rich protein family Gloverin PF10793.7 001312013.1_40323001_3 - 5.4e-51 172.5 6.7 7.2e-51 172.1 6.7 1.1 1 0 0 1 1 1 1 Gloverin-like protein Attacin_C PF03769.13 001312013.1_40323001_3 - 3.7e-05 23.7 1.7 5.7e-05 23.1 1.7 1.2 1 0 0 1 1 1 1 Attacin, C-terminal region Attacin_C PF03769.13 001312415.1_40322001_3 - 5.1e-38 129.8 4.6 3.8e-34 117.3 0.3 2.9 1 1 2 3 3 3 2 Attacin, C-terminal region Attacin_N PF03768.13 001312415.1_40322001_3 - 3.6e-09 36.5 6.2 3.6e-09 36.5 6.2 1.9 2 0 0 2 2 2 1 Attacin, N-terminal region OMP_b-brl PF13505.4 001312415.1_40322001_3 - 0.0058 16.6 9.6 0.015 15.3 9.6 1.6 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain Ferritin PF00210.22 001319786.1_04823001_2 - 7.4e-08 32.3 0.1 1.2e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Codanin-1_C PF15296.4 001319786.1_04823001_2 - 0.018 15.0 0.1 0.035 14.1 0.1 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus OS-D PF03392.11 001311219.1_49322001_2 - 3.9e-36 122.9 8.1 5.2e-36 122.5 8.1 1.2 1 0 0 1 1 1 1 Insect pheromone-binding family, A10/OS-D NDK PF00334.17 001311441.1_40222001_2 - 1.1e-53 180.8 0.0 1.3e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4926 PF16277.3 001311441.1_40222001_2 - 0.18 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) adh_short PF00106.23 001304753.1_53822001_1 - 1.9e-40 138.3 0.1 2.4e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001304753.1_53822001_1 - 1.7e-22 80.0 0.0 2.5e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.17 001304753.1_53822001_1 - 8.9e-08 31.3 0.2 1.2e-07 30.8 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.8 001304753.1_53822001_1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001304753.1_53822001_1 - 0.00021 20.7 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001304753.1_53822001_1 - 0.0017 17.7 0.1 0.0025 17.1 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.13 001304753.1_53822001_1 - 0.0032 16.5 0.1 0.0053 15.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Hemocyanin_C PF03723.12 001309063.1_33325001_1 - 2.3e-82 275.9 0.0 3.4e-82 275.3 0.0 1.3 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_M PF00372.17 001309063.1_33325001_1 - 3.1e-79 265.8 0.2 4.8e-79 265.2 0.2 1.3 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_N PF03722.12 001309063.1_33325001_1 - 1.6e-23 83.4 0.0 4.1e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Hemocyanin, all-alpha domain Tyrosinase PF00264.18 001309063.1_33325001_1 - 7.5e-08 32.8 1.7 1.2e-07 32.1 1.7 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase eIF3g PF12353.6 001312080.1_40322001_3 - 1.6e-40 138.2 1.1 3e-40 137.4 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.20 001312080.1_40322001_3 - 1.7e-13 50.0 0.0 3.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001312080.1_40322001_3 - 0.083 12.6 1.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF2294 PF10057.7 001316704.1_12323001_1 - 0.0054 16.7 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) Exo_endo_phos PF03372.21 001316704.1_12323001_1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AP3D1 PF06375.9 001316704.1_12323001_3 - 0.0033 17.6 12.3 0.0049 17.0 12.3 1.3 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 OAD_gamma PF04277.11 001316704.1_12323001_3 - 0.57 10.7 4.3 0.86 10.1 4.3 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF788 PF05620.9 001316704.1_12323001_3 - 1.7 8.4 6.6 2.6 7.8 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) YMF19 PF02326.13 001316704.1_12323001_3 - 2.2 9.0 6.8 4.1 8.1 6.8 1.4 1 0 0 1 1 1 0 Plant ATP synthase F0 ETRAMP PF09716.8 001316704.1_12323001_3 - 3.1 7.8 14.6 4.6 7.3 14.6 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) 7tm_6 PF02949.18 001312667.1_01923001_1 - 1.8e-22 79.7 21.2 1.8e-22 79.7 21.2 1.3 1 1 0 1 1 1 1 7tm Odorant receptor Aminotran_1_2 PF00155.19 001311700.1_40224001_1 - 9.1e-85 284.9 0.0 1.1e-84 284.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Lectin_C PF00059.19 001311353.1_40223001_3 - 2.6e-07 31.2 2.5 0.0039 17.8 0.1 2.8 3 0 0 3 3 3 2 Lectin C-type domain DUF4816 PF16086.3 001311355.1_40224001_2 - 6.2e-51 170.0 202.1 8.3e-13 48.0 36.1 8.0 2 2 6 8 8 8 8 Domain of unknown function (DUF4816) YTV PF07639.9 001311355.1_40224001_2 - 9.2 6.3 26.2 8.4 6.4 3.1 5.2 3 2 2 5 5 5 0 YTV bZIP_1 PF00170.19 001311871.1_40324001_2 - 6.8e-08 32.4 10.0 1.3e-07 31.5 10.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001311871.1_40324001_2 - 0.00045 20.1 12.3 0.00076 19.4 12.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001311871.1_40324001_2 - 0.16 12.3 7.5 0.33 11.4 7.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor RRM_1 PF00076.20 001315635.1_05025001_3 - 3.9e-21 74.5 0.1 1.5e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001315635.1_05025001_3 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif AdoHcyase PF05221.15 001312113.1_40324001_1 - 9.2e-130 432.0 0.0 8.4e-66 222.0 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.19 001312113.1_40324001_1 - 5.7e-83 276.7 2.9 9.3e-83 276.0 2.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.17 001312113.1_40324001_1 - 7.6e-09 35.0 0.1 1.4e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.10 001312113.1_40324001_1 - 0.00075 19.0 0.2 0.0013 18.2 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.19 001312113.1_40324001_1 - 0.0065 16.1 0.2 0.011 15.3 0.2 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.16 001312113.1_40324001_1 - 0.0096 16.0 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain ENOD40 PF08247.9 001312113.1_40324001_2 - 0.41 10.6 2.6 1.2 9.1 2.6 1.9 1 0 0 1 1 1 0 ENOD40 protein Ras PF00071.20 001304981.1_04824001_2 - 1e-56 190.9 0.0 1.5e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001304981.1_04824001_2 - 1.2e-31 109.3 0.0 1.9e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001304981.1_04824001_2 - 2.6e-11 43.2 0.0 3.5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001304981.1_04824001_2 - 1.9e-06 27.8 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001304981.1_04824001_2 - 0.00047 19.4 0.0 0.00073 18.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001304981.1_04824001_2 - 0.0019 17.7 0.1 0.036 13.5 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001304981.1_04824001_2 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.14 001304981.1_04824001_2 - 0.022 14.5 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Astacin PF01400.22 001309129.1_42622001_1 - 3.3e-44 150.7 0.0 4.2e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Glyco_hydro_18 PF00704.26 001309107.1_42629001_3 - 1e-189 629.7 4.1 3e-94 316.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_14 PF01607.22 001309107.1_42629001_3 - 6.6e-12 45.3 5.5 1.2e-11 44.4 5.5 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Chitin_bind_4 PF00379.21 001311833.1_40322001_1 - 3.7e-15 56.1 8.1 3.7e-15 56.1 8.1 1.8 2 0 0 2 2 2 1 Insect cuticle protein LVIVD PF08309.9 001311833.1_40322001_1 - 0.093 11.9 1.1 0.17 11.1 1.1 1.4 1 0 0 1 1 1 0 LVIVD repeat TRAP_beta PF05753.12 001311425.1_40222001_2 - 7e-64 214.3 0.4 9.5e-64 213.9 0.4 1.1 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) p450 PF00067.20 001319825.1_10524001_2 - 8.2e-97 324.7 0.3 9.5e-97 324.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chitin_bind_4 PF00379.21 001311522.1_40223001_3 - 2.9e-15 56.4 0.3 2.9e-15 56.4 0.3 1.7 2 0 0 2 2 2 1 Insect cuticle protein COesterase PF00135.26 001315623.1_05025001_1 - 1.1e-153 512.7 0.0 1.3e-153 512.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001315623.1_05025001_1 - 0.00026 20.8 1.3 0.0069 16.1 1.3 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.23 001312841.1_40323001_1 - 6.8e-08 32.1 0.2 1.1e-07 31.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001312841.1_40323001_1 - 3e-06 26.9 0.1 4.2e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase E1_DerP2_DerF2 PF02221.13 001312181.1_40322001_1 - 2.1e-20 73.4 0.9 2.5e-20 73.1 0.9 1.1 1 0 0 1 1 1 1 ML domain MRJP PF03022.14 001311432.1_40225001_1 - 1.9e-89 299.7 0.0 2.4e-89 299.4 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein PBP_GOBP PF01395.20 001311216.1_49322001_1 - 7.9e-16 58.1 6.9 1e-15 57.7 6.9 1.1 1 0 0 1 1 1 1 PBP/GOBP family RNA_pol_A_bac PF01000.24 001311216.1_49322001_1 - 0.05 13.8 0.1 0.092 13.0 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain Proteasome PF00227.24 001311542.1_40222001_1 - 1.3e-32 112.7 0.1 1.6e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DnaJ_C PF01556.16 001319787.1_04824001_1 - 9.6e-42 142.4 0.3 1.3e-41 142.0 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 001319787.1_04824001_1 - 1.6e-28 98.4 5.6 2.6e-28 97.8 5.6 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.4 001319787.1_04824001_1 - 0.053 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein OS-D PF03392.11 001311215.1_49322001_1 - 9.8e-36 121.6 0.4 9.8e-36 121.6 0.4 2.1 3 0 0 3 3 3 1 Insect pheromone-binding family, A10/OS-D Sec62 PF03839.14 001311215.1_49322001_3 - 0.0081 15.6 3.8 0.01 15.2 3.8 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 FAD_binding_1 PF00667.18 001316702.1_12325001_1 - 2.7e-77 259.2 0.0 3.7e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.23 001316702.1_12325001_1 - 2.4e-33 115.2 0.3 5.5e-33 114.1 0.3 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.19 001316702.1_12325001_1 - 1.2e-18 67.6 0.2 3.2e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain zf-RING_4 PF14570.4 001316702.1_12325001_1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Actin PF00022.17 001308859.1_14023001_1 - 4.6e-153 509.5 0.0 1.5e-152 507.8 0.0 1.6 1 1 0 1 1 1 1 Actin LIM PF00412.20 001305249.1_01724001_1 - 9.1e-34 115.3 21.4 2.4e-18 66.0 2.6 2.4 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.27 001305249.1_01724001_1 - 4e-19 68.0 0.3 7.2e-19 67.2 0.3 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001305249.1_01724001_1 - 0.00035 20.3 0.2 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain Vps39_2 PF10367.7 001305249.1_01724001_1 - 0.74 10.1 5.0 7 7.0 0.6 3.1 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 Aminotran_1_2 PF00155.19 001311404.1_40223001_3 - 3.8e-69 233.5 0.0 5e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.17 001311404.1_40223001_3 - 0.00037 19.4 0.0 0.0017 17.3 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DUF1676 PF07898.11 001311819.1_40323001_2 - 3e-24 85.8 0.7 1.3e-23 83.8 0.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1676) Pacs-1 PF10254.7 001311819.1_40323001_2 - 0.021 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein 7tm_6 PF02949.18 001312671.1_01923001_1 - 3.1e-100 335.2 11.8 3.1e-100 335.2 11.8 1.5 2 0 0 2 2 2 1 7tm Odorant receptor 7tm_7 PF08395.10 001312671.1_01923001_1 - 4.1e-07 29.4 7.7 4.1e-07 29.4 7.7 4.4 3 2 1 4 4 4 1 7tm Chemosensory receptor Trehalose_recp PF06151.11 001312671.1_01923001_1 - 0.00065 18.3 1.8 0.00065 18.3 1.8 2.4 2 0 0 2 2 2 1 Trehalose receptor Proteasome PF00227.24 001311493.1_40222001_2 - 6.7e-47 159.3 0.3 8.4e-47 159.0 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001311493.1_40222001_2 - 2.3e-14 52.6 0.0 3.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Claudin_2 PF13903.4 001308566.1_42623001_3 - 4.8e-41 140.5 1.7 6.4e-41 140.1 1.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction NDUF_B12 PF08122.10 001308566.1_42623001_3 - 0.2 11.6 0.4 0.82 9.6 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Chitin_bind_4 PF00379.21 001311759.1_40222001_3 - 1.9e-15 57.0 3.1 2.8e-15 56.4 3.1 1.2 1 0 0 1 1 1 1 Insect cuticle protein GSHPx PF00255.17 001312488.1_40322001_1 - 7e-39 131.6 0.1 9.9e-39 131.1 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 001312488.1_40322001_1 - 1.8e-06 27.7 0.1 2.9e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Ald_Xan_dh_C2 PF02738.16 001312670.1_01928001_1 - 7.8e-119 397.5 0.0 1.2e-118 396.9 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.18 001312670.1_01928001_1 - 8.2e-26 89.6 0.3 2.1e-25 88.3 0.3 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.20 001312670.1_01928001_1 - 4.3e-24 84.9 0.1 9.4e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001312670.1_01928001_1 - 6.1e-24 84.0 0.0 1.8e-23 82.5 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_5 PF00941.19 001312670.1_01928001_1 - 6.3e-16 58.4 0.0 1.3e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2 PF00111.25 001312670.1_01928001_1 - 0.0008 19.2 0.4 0.0008 19.2 0.4 2.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.4 001312670.1_01928001_1 - 0.15 12.4 5.4 0.59 10.6 5.4 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain JAB PF01398.19 001311414.1_40223001_1 - 2e-33 114.8 0.0 4.6e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.4 001311414.1_40223001_1 - 3.7e-33 114.2 0.4 6.4e-33 113.4 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function FAM176 PF14851.4 001311414.1_40223001_1 - 0.38 10.3 3.4 0.69 9.5 3.4 1.3 1 0 0 1 1 1 0 FAM176 family Trypsin PF00089.24 001311573.1_40223001_1 - 4.9e-39 134.3 0.0 1.3e-38 132.9 0.0 1.7 2 0 0 2 2 2 1 Trypsin PBP_GOBP PF01395.20 001311239.1_49322001_3 - 1.8e-17 63.4 2.8 2.7e-17 62.8 2.8 1.2 1 0 0 1 1 1 1 PBP/GOBP family Thymosin PF01290.18 001302098.1_33321001_1 - 1.3e-46 155.9 25.0 1.4e-16 59.8 3.2 3.1 2 1 1 3 3 3 3 Thymosin beta-4 family WH2 PF02205.18 001302098.1_33321001_1 - 0.0056 16.3 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 2 WH2 motif DUF4522 PF15022.4 001302098.1_33321001_1 - 0.012 15.7 4.8 6.4 6.9 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4522) HSP20 PF00011.19 001312449.1_40322001_3 - 5.6e-27 93.7 0.0 8.5e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.16 001312449.1_40322001_3 - 7.9e-06 25.9 0.6 1.6e-05 24.9 0.6 1.5 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal Cupredoxin_1 PF13473.4 001312449.1_40322001_3 - 0.083 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain DUF3581 PF12119.6 001312449.1_40322001_3 - 0.13 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) Lipase PF00151.17 001304726.1_04824001_3 - 3.4e-60 204.0 0.0 5.8e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Lipase Ferritin PF00210.22 001312106.1_40323001_2 - 1.1e-08 35.0 5.9 1.6e-08 34.5 5.9 1.2 1 0 0 1 1 1 1 Ferritin-like domain TMEM192 PF14802.4 001312106.1_40323001_2 - 0.001 18.1 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 TMEM192 family Acid_phosphat_B PF03767.12 001312106.1_40323001_2 - 0.024 14.1 0.3 0.035 13.6 0.3 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Ribosomal_S4e PF00900.18 001312354.1_40322001_2 - 3.7e-36 122.8 0.6 2.5e-35 120.1 0.1 2.2 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.3 001312354.1_40322001_2 - 3.4e-27 93.7 0.1 5.7e-27 93.0 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.10 001312354.1_40322001_2 - 3.1e-21 75.0 4.8 6.3e-21 74.1 4.8 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.23 001312354.1_40322001_2 - 2.3e-09 36.6 0.4 4.2e-09 35.8 0.1 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.27 001312354.1_40322001_2 - 1.2e-06 28.1 0.0 4.5e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 KOW motif Pyridoxal_deC PF00282.17 001317023.1_40125001_3 - 1.7e-162 540.3 0.0 2e-162 540.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.19 001317023.1_40125001_3 - 0.0036 16.5 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.17 001317023.1_40125001_3 - 0.068 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SepSecS PF05889.11 001317023.1_40125001_3 - 0.081 11.5 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS PBP_GOBP PF01395.20 001311242.1_49322001_1 - 8.1e-22 77.4 0.1 1.5e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 PBP/GOBP family COesterase PF00135.26 001316701.1_12324001_1 - 1.1e-158 529.2 1.8 1.3e-158 529.0 1.8 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001316701.1_12324001_1 - 9.9e-08 31.9 0.0 3e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Amidase_2 PF01510.23 001309000.1_33322001_3 - 3.8e-22 78.9 0.2 5.3e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Ion_trans PF00520.29 001316703.1_12329001_1 - 4.9e-244 805.2 89.7 1.1e-71 240.8 10.7 4.1 4 0 0 4 4 4 4 Ion transport protein Na_trans_cytopl PF11933.6 001316703.1_12329001_1 - 1.9e-42 145.4 7.7 1.9e-42 145.4 7.7 2.2 2 1 0 2 2 2 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.11 001316703.1_12329001_1 - 2.5e-35 122.4 1.5 2.5e-35 122.4 1.5 2.7 3 0 0 3 3 3 1 Sodium ion transport-associated PKD_channel PF08016.10 001316703.1_12329001_1 - 7.3e-17 61.0 73.5 1.9e-05 23.4 6.0 9.3 5 3 3 8 8 8 7 Polycystin cation channel GPHH PF16905.3 001316703.1_12329001_1 - 1.3e-06 28.0 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated SieB PF14163.4 001316703.1_12329001_1 - 1.4 8.2 7.9 1.5 8.2 0.1 4.1 4 0 0 4 4 4 0 Super-infection exclusion protein B UPF0239 PF06783.9 001316703.1_12329001_1 - 2.1 8.4 5.7 0.24 11.5 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) p450 PF00067.20 001316709.1_12324001_3 - 5.4e-78 262.7 0.2 6.7e-78 262.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 N_methyl PF07963.10 001316709.1_12324001_3 - 1.9 8.1 4.0 3.3 7.3 4.0 1.4 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif Lipocalin PF00061.21 001311545.1_40222001_3 - 1.4e-14 54.3 0.6 2e-14 53.9 0.6 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.10 001311545.1_40222001_3 - 6.5e-05 22.8 0.2 9.8e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.11 001311545.1_40222001_3 - 0.028 14.1 0.9 0.057 13.2 0.7 1.8 1 1 0 1 1 1 0 Triabin p450 PF00067.20 001319827.1_10524001_1 - 1.8e-89 300.5 0.2 2.4e-89 300.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Biopterin_H PF00351.19 001317015.1_40125001_2 - 5.8e-162 538.2 0.2 7.4e-162 537.9 0.2 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT_4 PF13291.4 001317015.1_40125001_2 - 0.0033 17.8 0.0 0.0081 16.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT PF01842.23 001317015.1_40125001_2 - 0.13 11.9 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 ACT domain Ribosomal_L1 PF00687.19 001305501.1_42622001_1 - 1.4e-43 148.9 2.5 1.7e-43 148.6 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NMD3 PF04981.11 001311615.1_40224001_2 - 2.5e-79 266.0 1.8 3.2e-79 265.7 1.8 1.1 1 0 0 1 1 1 1 NMD3 family Nif11 PF07862.9 001311615.1_40224001_2 - 0.05 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function DUF1289 PF06945.11 001311615.1_40224001_2 - 0.096 12.4 3.2 11 5.8 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) DZR PF12773.5 001311615.1_40224001_2 - 1.3 8.9 10.9 46 4.0 4.6 2.9 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_S24 PF00717.21 001312044.1_40322001_1 - 3.5e-10 39.5 0.1 5.5e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like CDC48_2 PF02933.15 001312044.1_40322001_1 - 0.076 12.7 0.2 6.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Laps PF10169.7 001312012.1_40322001_3 - 6.3e-34 117.2 18.4 7.9e-34 116.9 18.4 1.0 1 0 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.7 001312012.1_40322001_3 - 0.00018 21.5 5.1 0.00018 21.5 5.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) G5 PF07501.10 001312012.1_40322001_3 - 0.0041 17.4 3.0 0.0041 17.4 3.0 2.1 1 1 1 2 2 2 1 G5 domain 7tm_6 PF02949.18 001316708.1_12323001_1 - 5e-97 324.6 4.5 7.3e-97 324.1 4.5 1.2 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 001316708.1_12323001_1 - 6.3e-07 28.8 5.7 6.3e-07 28.8 5.7 3.4 3 1 0 3 3 3 3 7tm Chemosensory receptor Trehalose_recp PF06151.11 001316708.1_12323001_1 - 0.0011 17.5 11.4 0.0012 17.3 3.2 2.2 2 0 0 2 2 2 2 Trehalose receptor dsrm PF00035.24 001316991.1_04822001_1 - 3.8e-21 75.4 0.1 2.1e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.5 001316991.1_04822001_1 - 4.9e-10 39.4 3.2 0.0009 19.3 0.4 3.7 2 2 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 AAT PF03417.14 001317024.1_40124001_1 - 8.9e-41 139.9 0.0 1.2e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase PBP_GOBP PF01395.20 001311222.1_49322001_2 - 3.2e-22 78.7 0.2 4.7e-22 78.2 0.2 1.2 1 0 0 1 1 1 1 PBP/GOBP family DUF3456 PF11938.6 001315631.1_05022001_1 - 0.13 12.7 0.7 0.24 11.8 0.3 1.7 1 1 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP WD40 PF00400.30 001311454.1_40223001_2 - 1.1e-47 158.9 28.0 1.2e-07 32.1 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001311454.1_40223001_2 - 7.6e-10 38.8 1.1 0.037 14.2 0.0 4.9 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.3 001311454.1_40223001_2 - 0.0018 17.6 0.0 0.83 8.8 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.6 001311454.1_40223001_2 - 0.01 14.4 7.0 0.22 10.0 0.1 4.2 3 1 2 5 5 5 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.3 001311454.1_40223001_2 - 0.038 12.8 0.1 6.9 5.4 0.0 3.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FA_desaturase PF00487.22 001312665.1_01923001_1 - 1.9e-13 50.7 15.9 3e-13 50.0 15.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase JHBP PF06585.9 001311634.1_40223001_2 - 5.4e-63 212.2 0.0 7.2e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) DUF4403 PF14356.4 001311634.1_40223001_2 - 0.066 11.7 0.0 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) GST_N_3 PF13417.4 001312666.1_01923001_3 - 2.4e-13 50.1 0.0 4.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001312666.1_01923001_3 - 2.4e-12 46.9 0.0 1.1e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001312666.1_01923001_3 - 5.3e-11 42.5 0.1 9e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001312666.1_01923001_3 - 9.2e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001312666.1_01923001_3 - 1e-06 28.8 0.0 2.4e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001312666.1_01923001_3 - 1.7e-06 28.0 0.1 3.3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.20 001315626.1_05027001_1 - 6.3e-43 144.3 0.2 2.5e-21 75.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001315626.1_05027001_1 - 1.7e-08 34.0 0.0 8.8e-05 22.0 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001315626.1_05027001_1 - 0.01 15.5 0.0 6.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.4 001315626.1_05027001_1 - 0.029 14.5 0.0 0.81 9.8 0.0 2.8 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF3357 PF11837.6 001308415.1_10523001_1 - 0.13 12.6 7.9 2.6 8.4 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Chorion_3 PF05387.9 001308415.1_10523001_3 - 4.3e-65 220.0 51.3 4.2e-64 216.7 37.7 3.1 2 1 0 2 2 2 1 Chorion family 3 Serpin PF00079.18 001309033.1_33323001_1 - 5.5e-90 302.2 6.4 6.3e-90 302.0 6.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pkinase PF00069.23 001319781.1_04824001_1 - 9.5e-76 254.5 0.0 1.2e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001319781.1_04824001_1 - 4e-37 127.8 0.0 5.6e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.27 001319781.1_04824001_1 - 1.9e-15 57.1 0.1 5.4e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.4 001319781.1_04824001_1 - 6.7e-10 38.6 0.0 1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.22 001319781.1_04824001_1 - 1.6e-08 34.9 0.9 4.4e-08 33.6 0.9 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.4 001319781.1_04824001_1 - 0.0027 18.0 0.0 0.0064 16.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain FTA2 PF13095.4 001319781.1_04824001_1 - 0.0074 15.8 0.4 1.2 8.5 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 DUF753 PF05444.10 001311872.1_40323001_1 - 0.06 13.2 17.4 0.27 11.1 2.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF753) Ank_2 PF12796.5 001312100.1_40323001_1 - 2.5e-19 69.5 0.2 6.5e-19 68.2 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001312100.1_40323001_1 - 4.3e-19 68.2 0.6 1.5e-10 41.0 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.28 001312100.1_40323001_1 - 1.2e-18 66.5 3.2 4.1e-08 33.2 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.4 001312100.1_40323001_1 - 4e-16 57.4 0.4 7.2e-05 22.8 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.4 001312100.1_40323001_1 - 8.1e-15 54.9 0.4 4.3e-08 33.4 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ras PF00071.20 001319789.1_04824001_2 - 4.2e-65 218.1 0.6 5.7e-65 217.7 0.6 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001319789.1_04824001_2 - 2.6e-36 124.3 0.3 5e-36 123.4 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001319789.1_04824001_2 - 2.2e-17 62.9 0.1 3.2e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001319789.1_04824001_2 - 9e-06 25.2 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001319789.1_04824001_2 - 2.6e-05 24.1 0.5 0.14 11.9 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001319789.1_04824001_2 - 7e-05 22.1 0.6 0.00013 21.3 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001319789.1_04824001_2 - 9.7e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.8 001319789.1_04824001_2 - 0.00012 21.4 0.1 0.0002 20.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.4 001319789.1_04824001_2 - 0.16 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Serpin PF00079.18 001309057.1_33323001_1 - 1.5e-59 202.1 5.1 1.9e-59 201.7 5.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1280 PF06918.12 001309057.1_33323001_1 - 0.11 12.0 0.2 0.11 12.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1280) DNA_pol_A_exo1 PF01612.18 001309057.1_33323001_1 - 0.13 11.8 1.0 5 6.7 0.0 2.3 1 1 1 2 2 2 0 3'-5' exonuclease Proteasome PF00227.24 001312242.1_40322001_2 - 1.3e-55 187.7 0.0 1.7e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001312242.1_40322001_2 - 4.6e-14 51.6 0.1 7.7e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature COesterase PF00135.26 001316706.1_12324001_1 - 2.3e-155 518.3 0.0 2.6e-155 518.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001316706.1_12324001_1 - 1.4e-06 28.1 0.8 0.0036 17.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold PBP_GOBP PF01395.20 001311217.1_49322001_1 - 5.9e-18 65.0 0.4 7.8e-18 64.6 0.4 1.2 1 0 0 1 1 1 1 PBP/GOBP family PBP_GOBP PF01395.20 001308404.1_10522001_2 - 1.5e-22 79.7 0.1 2.1e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 PBP/GOBP family COesterase PF00135.26 001316705.1_12324001_1 - 3.6e-163 544.0 0.0 4.2e-163 543.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001316705.1_12324001_1 - 1e-08 35.2 0.0 3.3e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L1 PF00687.19 001311456.1_40222001_2 - 3.4e-43 147.6 2.9 4.1e-43 147.4 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family GHL13 PF14883.4 001311456.1_40222001_2 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 GST_N_3 PF13417.4 001309050.1_33322001_2 - 3.9e-19 68.7 0.1 6.9e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001309050.1_33322001_2 - 1.1e-13 51.1 0.0 2.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001309050.1_33322001_2 - 2.8e-12 46.7 0.0 7.4e-12 45.3 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001309050.1_33322001_2 - 8.6e-10 38.6 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001309050.1_33322001_2 - 6.7e-09 35.7 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001309050.1_33322001_2 - 2.3e-05 24.1 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 001309050.1_33322001_2 - 0.00019 22.0 0.0 0.0008 20.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.22 001309050.1_33322001_2 - 0.0013 18.7 0.0 0.081 13.0 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin PBP_GOBP PF01395.20 001311227.1_49322001_2 - 8.2e-12 45.2 6.5 1.9e-06 27.9 0.3 2.4 2 0 0 2 2 2 2 PBP/GOBP family DUF4816 PF16086.3 001311590.1_40225001_1 - 2.5e-57 190.4 180.3 2e-13 49.9 32.1 8.3 2 2 6 8 8 8 8 Domain of unknown function (DUF4816) Cornifin PF02389.13 001311590.1_40225001_1 - 0.0013 18.8 3.0 0.0013 18.8 3.0 1.9 2 0 0 2 2 2 1 Cornifin (SPRR) family TGF_beta PF00019.18 001312108.1_40323001_1 - 0.015 16.0 2.0 0.029 15.1 2.0 1.4 1 0 0 1 1 1 0 Transforming growth factor beta like domain Chitin_bind_4 PF00379.21 001311447.1_40222001_3 - 1.1e-11 45.0 1.1 1.9e-11 44.2 1.1 1.4 1 0 0 1 1 1 1 Insect cuticle protein Trypsin PF00089.24 001311555.1_40223001_1 - 1.4e-46 159.0 0.0 1.9e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001311555.1_40223001_1 - 0.00053 20.7 0.0 0.001 19.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain AAA_18 PF13238.4 001311555.1_40223001_2 - 0.016 15.6 0.6 0.35 11.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain TFIID_NTD2 PF04494.13 001312259.1_40325001_3 - 5.5e-40 136.5 7.6 9e-40 135.9 7.6 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.30 001312259.1_40325001_3 - 6.1e-40 134.4 31.6 1.4e-10 41.4 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001312259.1_40325001_3 - 2.1e-08 34.2 0.1 0.23 11.6 0.0 5.4 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 001312259.1_40325001_3 - 0.00062 18.4 1.1 0.0038 15.8 0.1 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.3 001312259.1_40325001_3 - 0.017 14.0 4.8 2.1 7.1 0.8 3.8 3 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PBP_GOBP PF01395.20 001311231.1_49322001_2 - 2.1e-25 89.0 2.0 2.5e-25 88.7 2.0 1.1 1 0 0 1 1 1 1 PBP/GOBP family SUI1 PF01253.20 001311370.1_40222001_2 - 1.5e-26 92.5 0.3 2.5e-26 91.9 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 OS-D PF03392.11 001311218.1_49322001_2 - 6.5e-36 122.2 6.9 9.9e-36 121.6 6.9 1.3 1 0 0 1 1 1 1 Insect pheromone-binding family, A10/OS-D Ribosomal_L44 PF00935.17 001308413.1_10521001_1 - 3.1e-32 110.8 17.2 3.1e-32 110.8 17.2 1.7 1 1 0 1 1 1 1 Ribosomal protein L44 Chitin_bind_4 PF00379.21 001311409.1_40223001_1 - 0.0028 18.0 0.3 0.0069 16.8 0.3 1.7 1 0 0 1 1 1 1 Insect cuticle protein COesterase PF00135.26 001311249.1_49325001_1 - 2.1e-157 525.0 0.0 2.6e-157 524.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001311249.1_49325001_1 - 3.7e-05 23.5 0.7 0.058 13.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold p450 PF00067.20 001319831.1_10524001_3 - 1.7e-68 231.3 0.0 2.2e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Galactosyl_T PF01762.19 001309088.1_42623001_1 - 1.8e-44 151.7 1.9 2.8e-44 151.1 1.9 1.3 1 0 0 1 1 1 1 Galactosyltransferase TCTP PF00838.15 001311430.1_40222001_2 - 5.9e-65 218.4 5.6 6.9e-65 218.2 5.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Guanylate_cyc PF00211.18 001304982.1_04826001_2 - 2.2e-58 196.8 0.0 3.2e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.12 001304982.1_04826001_2 - 4.8e-41 140.4 0.1 4.5e-40 137.2 0.1 2.0 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.13 001304982.1_04826001_2 - 9.3e-09 35.3 0.0 2.8e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Haem-NO-binding ETC_C1_NDUFA5 PF04716.12 001312069.1_40321001_3 - 1.8e-26 91.6 0.4 2.4e-26 91.2 0.4 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Cu-oxidase_3 PF07732.13 001317013.1_40127001_1 - 1.7e-35 121.5 1.2 5.3e-35 119.9 1.2 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.12 001317013.1_40127001_1 - 9e-32 109.5 7.7 5.1e-31 107.1 0.1 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.20 001317013.1_40127001_1 - 2.2e-28 99.2 0.0 3.4e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Lipocalin PF00061.21 001312829.1_40322001_3 - 0.014 15.4 1.4 0.022 14.8 0.7 1.5 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Kazal_1 PF00050.19 001311901.1_40322001_2 - 0.00037 20.3 5.1 0.00084 19.2 5.1 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 001311901.1_40322001_2 - 0.00038 20.5 4.4 0.0011 18.9 4.4 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain COesterase PF00135.26 001304730.1_04824001_3 - 9.2e-113 377.7 0.0 1.2e-112 377.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001304730.1_04824001_3 - 4.9e-06 26.4 0.1 1.2e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pox_H7 PF04787.10 001304730.1_04824001_3 - 0.026 14.9 0.1 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Late protein H7 Bax1-I PF01027.18 001311916.1_40323001_2 - 2.2e-47 161.4 34.6 3.8e-47 160.7 34.6 1.4 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7tm_6 PF02949.18 001312669.1_01923001_1 - 6e-26 91.1 7.7 8.5e-26 90.6 7.7 1.2 1 0 0 1 1 1 1 7tm Odorant receptor MIP PF00230.18 001309016.2_33322001_2 - 8.6e-65 218.5 16.1 1e-64 218.2 16.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein ODC_AZ PF02100.15 125350.1_06224120_1 - 3.1e-19 68.9 0.0 5.5e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribonuclease_3 PF00636.24 148209.1_00929120_2 - 3.6e-49 165.6 0.0 6.3e-24 84.5 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain PAZ PF02170.20 148209.1_00929120_2 - 1.2e-23 83.3 0.1 2.6e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 PAZ domain Ribonucleas_3_3 PF14622.4 148209.1_00929120_2 - 1.3e-23 83.4 0.1 1.3e-14 54.3 0.0 3.8 3 1 0 3 3 3 2 Ribonuclease-III-like dsrm PF00035.24 148209.1_00929120_2 - 0.0013 19.3 0.1 0.0027 18.2 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Dicer_dimer PF03368.12 148209.1_00929120_3 - 4.5e-23 81.1 0.0 1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.29 148209.1_00929120_3 - 1.8e-18 66.8 1.3 4.3e-17 62.4 0.4 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.27 148209.1_00929120_3 - 2e-15 56.9 0.3 8.1e-15 54.9 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.13 148209.1_00929120_3 - 4.9e-12 46.0 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribonuclease_3 PF00636.24 001352974.1_00929001_2 - 1.3e-49 167.0 0.0 6.3e-24 84.5 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain Dicer_dimer PF03368.12 001352974.1_00929001_2 - 4.6e-24 84.3 0.4 1e-22 80.0 0.0 2.8 2 0 0 2 2 2 1 Dicer dimerisation domain PAZ PF02170.20 001352974.1_00929001_2 - 9.2e-24 83.7 0.1 2.7e-23 82.2 0.1 1.8 1 0 0 1 1 1 1 PAZ domain Ribonucleas_3_3 PF14622.4 001352974.1_00929001_2 - 1.2e-23 83.6 0.1 1.3e-14 54.3 0.0 3.9 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.29 001352974.1_00929001_2 - 1.1e-18 67.5 1.3 4.3e-17 62.4 0.4 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.27 001352974.1_00929001_2 - 1.7e-15 57.1 0.3 8.1e-15 54.9 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.13 001352974.1_00929001_2 - 4.1e-12 46.3 0.0 1.3e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.24 001352974.1_00929001_2 - 1.6e-07 31.7 0.1 0.0027 18.2 0.1 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif SRP14 PF02290.13 001352974.1_00929001_2 - 0.051 13.8 0.7 8.7 6.7 0.3 3.2 3 0 0 3 3 3 0 Signal recognition particle 14kD protein Homeobox PF00046.27 001323809.1_40725001_3 - 4.1e-21 74.4 4.4 7.3e-21 73.6 4.4 1.4 1 0 0 1 1 1 1 Homeobox domain Inhibitor_I36 PF03995.11 001323809.1_40725001_3 - 0.015 15.0 0.7 0.086 12.7 1.0 2.2 2 0 0 2 2 2 0 Peptidase inhibitor family I36 wnt PF00110.17 001323816.1_40724001_3 - 2.1e-117 391.9 21.3 2.6e-117 391.6 21.3 1.1 1 0 0 1 1 1 1 wnt family Forkhead PF00250.16 001323833.1_40724001_3 - 5.9e-36 122.5 0.1 1.5e-35 121.3 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain HNF_C PF09354.8 001323833.1_40724001_3 - 4.1e-06 27.6 4.0 4.1e-06 27.6 4.0 3.6 4 1 0 4 4 4 1 HNF3 C-terminal domain HLH PF00010.24 001323807.1_40723001_1 - 6.3e-16 57.9 0.2 1e-15 57.3 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Patched PF02460.16 001323808.1_40729001_1 - 5.9e-54 183.3 17.2 1.1e-52 179.0 17.2 2.2 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.6 001323808.1_40729001_1 - 4.4e-31 107.6 8.4 4.4e-31 107.6 8.4 2.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Arm PF00514.21 001323814.1_40727001_2 - 1.4e-38 129.6 30.4 5.1e-06 26.2 0.1 11.0 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.18 001323814.1_40727001_2 - 7.1e-09 34.6 5.5 1e-06 27.5 3.2 3.1 3 0 0 3 3 3 1 Adaptin N terminal region KAP PF05804.10 001323814.1_40727001_2 - 7.1e-07 27.6 1.4 0.022 12.8 0.4 3.2 3 0 0 3 3 3 2 Kinesin-associated protein (KAP) HEAT_EZ PF13513.4 001323814.1_40727001_2 - 8.8e-07 29.1 9.5 0.32 11.4 0.1 5.8 4 1 1 5 5 5 3 HEAT-like repeat Cnd1 PF12717.5 001323814.1_40727001_2 - 9.5e-07 28.8 1.8 0.0016 18.4 0.6 3.5 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.4 001323814.1_40727001_2 - 2.3e-06 27.8 7.4 0.00078 19.6 0.9 4.5 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.20 001323814.1_40727001_2 - 3.6e-05 23.5 3.4 0.36 11.1 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat V-ATPase_H_N PF03224.12 001323814.1_40727001_2 - 0.00012 21.3 3.9 0.025 13.7 2.8 3.1 1 1 1 2 2 2 1 V-ATPase subunit H DUF3361 PF11841.6 001323814.1_40727001_2 - 0.00025 20.9 3.2 1.5 8.7 0.0 4.5 3 2 2 5 5 5 1 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.7 001323814.1_40727001_2 - 0.0029 17.5 1.2 0.018 15.0 0.2 2.9 2 1 1 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF383 PF04063.12 001323814.1_40727001_2 - 0.076 12.6 1.1 0.87 9.1 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF383) Pes-10 PF07149.9 001323814.1_40727001_2 - 0.13 11.2 0.2 1.4 7.7 0.0 2.3 2 1 1 3 3 3 0 Pes-10 Arm_2 PF04826.11 001323814.1_40727001_2 - 0.27 10.5 10.4 0.37 10.1 0.2 3.7 2 1 1 3 3 3 0 Armadillo-like RasGEF_N_2 PF14663.4 001323814.1_40727001_2 - 0.3 11.3 6.4 6.1 7.1 0.3 4.3 4 1 0 5 5 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cadherin PF00028.15 001323824.1_40729001_2 - 1.8e-215 698.1 50.7 2.7e-18 66.1 0.8 18.3 18 0 0 18 18 18 17 Cadherin domain Laminin_G_2 PF02210.22 001323824.1_40729001_2 - 9.5e-49 165.0 1.6 7e-26 91.1 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain Cadherin_C PF01049.15 001323824.1_40729001_2 - 8.8e-47 158.6 0.3 2.4e-46 157.2 0.3 1.8 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_1 PF00054.21 001323824.1_40729001_2 - 6.5e-32 110.4 0.0 3.4e-18 66.0 0.0 2.9 2 0 0 2 2 2 2 Laminin G domain Cadherin_3 PF16184.3 001323824.1_40729001_2 - 4.1e-17 62.1 29.4 0.068 13.1 0.0 13.0 12 0 0 12 12 12 6 Cadherin-like EGF PF00008.25 001323824.1_40729001_2 - 3.1e-09 36.8 55.5 9.3e-07 28.9 8.4 4.9 4 0 0 4 4 4 3 EGF-like domain Cadherin_2 PF08266.10 001323824.1_40729001_2 - 1.8e-06 27.6 0.8 3.6 7.3 0.1 7.0 7 0 0 7 7 7 2 Cadherin-like Laminin_G_3 PF13385.4 001323824.1_40729001_2 - 3.6e-06 27.1 0.1 0.068 13.2 0.0 3.7 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily cEGF PF12662.5 001323824.1_40729001_2 - 0.00065 19.5 4.3 0.00065 19.5 4.3 4.6 4 0 0 4 4 4 1 Complement Clr-like EGF-like DUF1080 PF06439.9 001323824.1_40729001_2 - 0.024 14.6 1.0 0.55 10.2 0.0 3.8 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1080) hEGF PF12661.5 001323824.1_40729001_2 - 0.16 12.5 43.5 0.016 15.7 8.3 4.9 4 0 0 4 4 4 0 Human growth factor-like EGF PKD PF00801.18 001323824.1_40729001_2 - 1.3 8.8 3.1 1.3e+02 2.4 0.2 4.3 4 0 0 4 4 4 0 PKD domain EGF_2 PF07974.11 001323824.1_40729001_2 - 1.6 9.1 58.2 0.05 13.9 6.0 4.8 5 0 0 5 5 4 0 EGF-like domain SIX1_SD PF16878.3 001323823.1_40724001_3 - 5.6e-46 155.5 0.3 2.5e-45 153.4 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeobox PF00046.27 001323823.1_40724001_3 - 3.2e-12 45.9 2.9 6.7e-12 44.9 1.1 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.9 001323823.1_40724001_3 - 4e-10 39.3 1.1 9e-10 38.2 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.20 001323823.1_40724001_3 - 0.13 12.2 0.0 0.13 12.2 0.0 2.0 3 0 0 3 3 3 0 Helix-turn-helix DUF3043 PF11241.6 001323823.1_40724001_3 - 0.79 9.6 2.9 1.4 8.8 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Hairy_orange PF07527.11 001323826.1_40723001_1 - 4e-16 58.8 0.1 8.1e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.24 001323826.1_40723001_1 - 2.1e-14 53.0 6.1 4.4e-14 52.0 6.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain p450 PF00067.20 001286882.1_33324001_2 - 7.1e-86 288.6 0.3 8.7e-86 288.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2551 PF10826.6 001286882.1_33324001_2 - 0.044 13.9 0.0 2.2 8.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2551) YebG PF07130.10 001286882.1_33324001_2 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 YebG protein Asp PF00026.21 001286878.1_33323001_1 - 3.1e-122 407.8 0.0 3.8e-122 407.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001286878.1_33323001_1 - 1.5e-14 54.5 0.5 7.9e-08 32.6 0.2 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.4 001286878.1_33323001_1 - 2.1e-06 27.5 0.0 1e-05 25.2 0.0 2.1 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal A1_Propeptide PF07966.10 001286878.1_33323001_1 - 0.00038 20.1 0.1 0.00067 19.3 0.1 1.4 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.4 001286878.1_33323001_1 - 0.0056 17.2 0.1 5.6 7.6 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease Neur_chan_LBD PF02931.21 001286883.1_33326001_1 - 7.9e-80 267.2 2.2 1.3e-79 266.5 0.9 1.9 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001286883.1_33326001_1 - 5.5e-76 255.6 0.7 8.3e-76 255.0 0.0 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Lys PF00062.18 001309053.1_33321001_1 - 1.2e-40 138.5 3.3 1.4e-40 138.3 3.3 1.0 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.18 001309053.1_33321001_1 - 0.0032 17.0 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Transglycosylas PF06737.12 001309053.1_33321001_1 - 0.095 13.2 4.5 0.45 11.1 4.5 1.9 1 1 0 1 1 1 0 Transglycosylase-like domain FA_desaturase PF00487.22 001286873.1_33324001_1 - 3.7e-15 56.3 14.9 3.7e-15 56.3 14.9 1.6 1 1 1 2 2 2 1 Fatty acid desaturase p450 PF00067.20 001308983.1_33324001_1 - 1.4e-61 208.5 0.1 1.8e-61 208.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 PX PF00787.22 001308983.1_33324001_1 - 0.00026 20.8 0.2 0.00069 19.4 0.2 1.7 1 0 0 1 1 1 1 PX domain MCR_gamma PF02240.14 001308983.1_33324001_1 - 0.0037 16.4 0.1 0.0073 15.4 0.1 1.4 1 0 0 1 1 1 1 Methyl-coenzyme M reductase gamma subunit Vpu PF00558.17 001308983.1_33324001_1 - 0.92 9.2 3.1 1.1 8.9 1.4 2.0 2 0 0 2 2 2 0 Vpu protein Lactamase_B_4 PF13691.4 001304980.1_04826001_2 - 1.2e-15 56.7 0.1 8.7e-14 50.8 0.0 3.3 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B_2 PF12706.5 001304980.1_04826001_2 - 9.4e-12 44.7 1.1 1.8e-08 34.0 0.4 3.4 2 2 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.25 001304980.1_04826001_2 - 0.032 14.1 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily FAT PF02259.21 001304984.1_04829001_2 - 1.8e-111 372.6 2.8 1.8e-111 372.6 2.8 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.25 001304984.1_04829001_2 - 4.5e-76 255.8 0.8 1.2e-73 247.9 0.2 2.5 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.6 001304984.1_04829001_2 - 1.7e-59 200.2 5.8 1.1e-56 191.0 0.9 4.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) FRB_dom PF08771.9 001304984.1_04829001_2 - 5.3e-42 142.1 3.2 9e-42 141.4 0.5 3.1 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain FATC PF02260.18 001304984.1_04829001_2 - 8.8e-17 60.5 2.3 3.6e-16 58.5 2.3 2.1 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.4 001304984.1_04829001_2 - 9.5e-12 45.0 9.1 0.0033 17.6 0.1 8.9 10 1 1 11 11 10 3 HEAT repeats HEAT PF02985.20 001304984.1_04829001_2 - 7.9e-07 28.7 6.8 0.22 11.7 0.0 9.4 9 0 0 9 9 8 1 HEAT repeat TPR_19 PF14559.4 001304984.1_04829001_2 - 0.00015 22.1 0.2 0.012 16.0 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.5 001304984.1_04829001_2 - 0.0083 16.6 12.5 0.25 11.8 0.2 6.1 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Tti2 PF10521.7 001304984.1_04829001_2 - 0.018 14.5 9.3 1.1 8.6 0.7 5.0 2 1 2 4 4 4 0 Tti2 family ANAPC3 PF12895.5 001304984.1_04829001_2 - 0.028 14.5 2.6 7.8 6.6 0.2 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.26 001304984.1_04829001_2 - 0.054 13.2 1.8 6.9 6.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.15 001304984.1_04829001_2 - 0.058 13.4 8.2 5.5 7.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4851 PF16143.3 001304984.1_04829001_2 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) TPR_7 PF13176.4 001304984.1_04829001_2 - 0.21 11.5 0.7 91 3.3 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CLASP_N PF12348.6 001304984.1_04829001_2 - 0.37 10.2 13.3 0.93 8.9 0.5 5.0 4 0 0 4 4 4 0 CLASP N terminal BP28CT PF08146.10 001304984.1_04829001_2 - 1.1 9.2 3.9 6.9 6.6 0.2 4.3 5 0 0 5 5 5 0 BP28CT (NUC211) domain TIP120 PF08623.8 001304984.1_04829001_2 - 1.1 8.9 6.4 2 8.0 0.1 4.3 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) EF-hand_1 PF00036.30 001304983.1_04823001_3 - 8.6e-13 46.7 4.2 0.00025 20.2 0.0 4.5 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.4 001304983.1_04823001_3 - 2.2e-09 36.4 4.6 0.052 13.4 0.2 4.7 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.4 001304983.1_04823001_3 - 4.6e-08 32.1 3.1 0.011 15.1 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.4 001304983.1_04823001_3 - 5.3e-07 29.9 2.5 0.0019 18.5 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001304983.1_04823001_3 - 4.6e-06 26.2 3.4 0.1 12.2 0.1 3.7 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001304983.1_04823001_3 - 0.029 14.5 1.4 4.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001304983.1_04823001_3 - 0.78 9.6 9.9 5.6 6.8 0.2 3.9 2 2 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Sod_Cu PF00080.18 001304974.1_04822001_3 - 1.8e-38 131.7 0.2 3.4e-38 130.8 0.2 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.24 001304974.1_04822001_3 - 4.2e-06 27.0 0.0 7.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain FAD_binding_1 PF00667.18 001319788.1_04826001_2 - 4e-76 255.3 0.0 5.5e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.23 001319788.1_04826001_2 - 1.8e-33 115.6 0.2 2.9e-33 114.9 0.2 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.19 001319788.1_04826001_2 - 1.3e-15 57.8 0.0 3.7e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain p450 PF00067.20 001354794.1_25325001_3 - 1.7e-89 300.6 7.4 8.4e-87 291.7 7.4 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001354795.1_25324001_3 - 1.7e-86 290.7 1.0 5.8e-84 282.3 1.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001354796.1_25324001_1 - 3.8e-81 273.0 7.4 1.5e-79 267.8 7.4 2.0 1 1 0 1 1 1 1 Cytochrome P450 7tm_1 PF00001.19 001314160.1_28523001_1 - 6.8e-55 186.0 15.3 6.8e-55 186.0 15.3 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001314160.1_28523001_1 - 1.6e-09 37.4 11.0 1.6e-09 37.4 11.0 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001314160.1_28523001_1 - 9.1e-05 21.8 13.6 9.1e-05 21.8 13.6 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001314160.1_28523001_1 - 0.0051 16.5 3.9 0.0051 16.5 3.9 3.3 1 1 1 3 3 3 1 Olfactory receptor Peptidase_S49_N PF08496.8 001314160.1_28523001_1 - 0.1 12.6 0.4 0.23 11.4 0.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal 7tm_1 PF00001.19 001314115.1_28524001_1 - 6.9e-52 176.2 5.6 9e-52 175.8 5.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.7 001314115.1_28524001_1 - 0.0003 20.1 5.8 0.00051 19.3 5.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.7 001314115.1_28524001_1 - 0.00043 19.6 8.1 0.00068 19.0 0.2 2.7 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx G-alpha PF00503.18 001314113.1_28524001_1 - 1e-114 383.3 6.2 1.4e-114 382.9 6.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001314113.1_28524001_1 - 4.9e-13 48.8 0.4 1.1e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001314113.1_28524001_1 - 0.0038 16.5 3.2 0.047 12.9 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region SNF PF00209.16 001314098.1_28526001_1 - 1.6e-217 723.2 33.9 2e-217 722.9 33.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4381 PF14316.4 001314098.1_28526001_1 - 4.9 7.2 5.3 54 3.9 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Ras PF00071.20 001314133.1_28526001_3 - 1.7e-61 206.4 0.2 2.2e-61 206.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001314133.1_28526001_3 - 2.8e-34 117.8 0.1 4.1e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001314133.1_28526001_3 - 2.3e-11 43.3 0.1 3.5e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001314133.1_28526001_3 - 2.2e-06 27.6 0.1 3.2e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.4 001314133.1_28526001_3 - 0.0011 19.1 0.0 0.0045 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.25 001314133.1_28526001_3 - 0.0019 17.7 0.1 0.0037 16.7 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001314133.1_28526001_3 - 0.012 15.4 0.3 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.4 001314133.1_28526001_3 - 0.074 13.3 0.1 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.25 001314133.1_28526001_3 - 0.14 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Ion_trans PF00520.29 001314083.1_28528001_3 - 3.8e-29 101.5 15.2 6.4e-29 100.8 15.2 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.9 001314083.1_28528001_3 - 1.6e-27 95.4 0.5 3.9e-27 94.1 0.5 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.10 001314083.1_28528001_3 - 2.1e-13 49.7 12.9 4.2e-09 35.5 2.5 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ank_2 PF12796.5 001314083.1_28528001_3 - 6.1e-09 36.2 3.0 2.4e-06 27.9 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.4 001314083.1_28528001_3 - 1e-05 25.4 0.7 0.24 12.0 0.0 4.3 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.4 001314083.1_28528001_3 - 5.2e-05 23.6 0.5 0.084 13.3 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF1635 PF07795.9 001314083.1_28528001_3 - 0.00039 20.3 2.4 0.00082 19.3 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) Ank PF00023.28 001314083.1_28528001_3 - 0.0028 17.9 0.4 0.014 15.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.4 001314083.1_28528001_3 - 0.01 16.1 0.0 5 7.5 0.0 3.1 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Hemocyanin_C PF03723.12 001314148.1_28525001_2 - 3.4e-71 239.3 0.1 4.7e-71 238.9 0.1 1.2 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_M PF00372.17 001314148.1_28525001_2 - 2.3e-70 236.7 0.1 3.3e-70 236.2 0.1 1.2 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_N PF03722.12 001314148.1_28525001_2 - 1.3e-21 77.3 0.2 7e-21 74.9 0.2 2.4 1 1 0 1 1 1 1 Hemocyanin, all-alpha domain Tyrosinase PF00264.18 001314148.1_28525001_2 - 3.2e-08 34.0 1.0 3.2e-08 34.0 1.0 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase Phage_P2_GpE PF06528.10 001314148.1_28525001_2 - 0.075 12.5 0.1 0.2 11.1 0.1 1.8 1 0 0 1 1 1 0 Phage P2 GpE Hemocyanin_M PF00372.17 001314143.1_28525001_3 - 5.2e-70 235.6 0.1 7.9e-70 235.0 0.1 1.3 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_C PF03723.12 001314143.1_28525001_3 - 1.1e-69 234.3 0.0 1.5e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_N PF03722.12 001314143.1_28525001_3 - 2.8e-16 60.0 0.0 7.3e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Hemocyanin, all-alpha domain Tyrosinase PF00264.18 001314143.1_28525001_3 - 2.3e-07 31.2 1.1 4.7e-07 30.2 1.1 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Syntaxin PF00804.23 001314093.1_28523001_1 - 8.5e-64 214.8 23.7 1.3e-63 214.2 23.7 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.17 001314093.1_28523001_1 - 5e-17 61.5 9.8 8.6e-17 60.8 1.6 3.0 3 0 0 3 3 2 1 SNARE domain Syntaxin_2 PF14523.4 001314093.1_28523001_1 - 4.1e-10 39.8 9.9 4.1e-10 39.8 9.9 2.4 1 1 1 2 2 2 1 Syntaxin-like protein LRRFIP PF09738.7 001314093.1_28523001_1 - 0.0047 16.4 8.6 0.0047 16.4 8.6 2.1 2 0 0 2 2 2 1 LRRFIP family AAA_13 PF13166.4 001314093.1_28523001_1 - 0.0095 14.5 19.8 0.013 14.1 19.8 1.1 1 0 0 1 1 1 1 AAA domain Uso1_p115_C PF04871.11 001314093.1_28523001_1 - 0.021 15.1 4.0 0.021 15.1 4.0 3.2 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF745 PF05335.11 001314093.1_28523001_1 - 0.025 14.2 21.0 0.079 12.6 10.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Laminin_II PF06009.10 001314093.1_28523001_1 - 0.039 13.8 14.1 0.021 14.7 6.6 2.5 2 0 0 2 2 2 0 Laminin Domain II Ntox34 PF15606.4 001314093.1_28523001_1 - 0.055 13.5 0.9 0.3 11.1 0.2 2.3 1 1 1 2 2 2 0 Bacterial toxin 34 MCPsignal PF00015.19 001314093.1_28523001_1 - 0.076 12.6 15.0 0.85 9.2 5.9 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WXG100 PF06013.10 001314093.1_28523001_1 - 0.11 12.6 10.6 1.5 9.0 0.8 3.9 4 1 0 4 4 4 0 Proteins of 100 residues with WXG T2SSF PF00482.21 001314093.1_28523001_1 - 0.27 11.1 6.4 0.11 12.3 1.2 2.5 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F TraF_2 PF13729.4 001314093.1_28523001_1 - 0.47 9.6 6.9 0.16 11.2 3.2 2.1 1 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein COG5 PF10392.7 001314093.1_28523001_1 - 0.48 10.5 9.1 1.4 8.9 3.1 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Lzipper-MIP1 PF14389.4 001314093.1_28523001_1 - 0.51 10.5 13.0 0.81 9.9 0.2 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1687 PF07955.9 001314093.1_28523001_1 - 0.61 10.4 5.0 0.27 11.6 0.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1687) FUSC PF04632.10 001314093.1_28523001_1 - 0.68 8.3 1.9 0.69 8.3 0.4 1.7 1 1 0 2 2 2 0 Fusaric acid resistance protein family Sec34 PF04136.13 001314093.1_28523001_1 - 0.73 9.6 14.5 0.67 9.7 5.3 3.2 2 1 1 3 3 3 0 Sec34-like family IFT46_B_C PF12317.6 001314093.1_28523001_1 - 1.1 8.8 11.8 0.061 12.9 5.0 2.0 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal TRPM_tetra PF16519.3 001314093.1_28523001_1 - 1.5 8.9 10.7 5.6 7.0 4.0 3.6 1 1 3 4 4 4 0 Tetramerisation domain of TRPM Syntaxin-6_N PF09177.9 001314093.1_28523001_1 - 1.8 9.1 14.8 0.24 11.8 5.8 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.10 001314093.1_28523001_1 - 2 8.8 12.9 2.7 8.4 1.1 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PilJ PF13675.4 001314093.1_28523001_1 - 2 8.4 7.1 5.1 7.0 0.2 3.4 2 2 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term APG6 PF04111.10 001314093.1_28523001_1 - 2 7.6 22.2 0.022 14.0 10.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 YtxH PF12732.5 001314093.1_28523001_1 - 2.8 8.4 13.0 15 6.1 5.3 3.6 1 1 1 2 2 2 0 YtxH-like protein SlyX PF04102.10 001314093.1_28523001_1 - 3.9 8.0 15.9 1.6 9.3 0.7 3.9 3 1 1 4 4 3 0 SlyX FlaC_arch PF05377.9 001314093.1_28523001_1 - 4.8 7.5 19.8 1.3 9.3 1.4 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) TBPIP PF07106.11 001314093.1_28523001_1 - 4.9 6.8 25.4 0.067 12.8 12.7 2.4 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Allexi_40kDa PF05549.9 001314093.1_28523001_1 - 5.3 6.3 13.3 0.97 8.8 6.6 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Fez1 PF06818.13 001314093.1_28523001_1 - 5.4 7.3 23.8 1.4 9.2 1.5 2.9 2 1 0 2 2 2 0 Fez1 DUF932 PF06067.9 001314093.1_28523001_1 - 6.4 6.3 13.9 0.22 11.1 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF932) TMPIT PF07851.11 001314093.1_28523001_1 - 9.4 5.2 21.1 4.2 6.4 12.3 2.4 1 1 0 2 2 2 0 TMPIT-like protein BBE PF08031.10 001314154.1_28529001_1 - 0.0027 17.7 4.7 1.4e+02 2.6 0.0 6.3 6 1 1 7 7 7 2 Berberine and berberine like cNMP_binding PF00027.27 001314154.1_28529001_2 - 7.8e-20 70.6 0.0 1.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.14 001314154.1_28529001_2 - 0.00014 21.6 0.8 0.00014 21.6 0.8 2.5 2 0 0 2 2 2 1 Ion channel Astacin PF01400.22 001314086.1_28523001_1 - 7.6e-61 204.9 0.0 1.1e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.21 001314086.1_28523001_1 - 2e-10 40.6 0.0 4.5e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu Peptidase_M66 PF10462.7 001314086.1_28523001_1 - 0.079 11.8 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.22 001314086.1_28523001_1 - 0.21 11.3 0.5 1 9.1 0.4 2.0 1 1 0 2 2 2 0 Matrixin Ras PF00071.20 001314178.1_28524001_2 - 1.2e-62 210.1 0.2 1.7e-62 209.7 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001314178.1_28524001_2 - 1.4e-34 118.7 0.1 2.7e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001314178.1_28524001_2 - 5.6e-12 45.3 0.1 8.3e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001314178.1_28524001_2 - 1.4e-06 28.2 0.1 2.1e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.4 001314178.1_28524001_2 - 0.00046 20.3 0.0 0.003 17.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.25 001314178.1_28524001_2 - 0.00075 18.9 0.1 0.0016 17.9 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001314178.1_28524001_2 - 0.0014 18.4 0.4 0.073 12.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.4 001314178.1_28524001_2 - 0.043 14.1 0.1 0.08 13.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.25 001314178.1_28524001_2 - 0.091 13.1 0.1 0.18 12.2 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Actin PF00022.17 001314162.1_28524001_2 - 1.5e-149 497.9 0.0 3.9e-149 496.6 0.0 1.6 1 1 0 1 1 1 1 Actin zf-RanBP PF00641.16 001170845.1_51224001_2 - 0.00035 19.7 1.2 0.00075 18.6 1.2 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others TolA_bind_tri PF16331.3 001170845.1_51224001_2 - 0.039 13.9 5.2 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation IncA PF04156.12 001170845.1_51224001_2 - 0.067 12.9 1.6 0.14 11.8 1.6 1.5 1 0 0 1 1 1 0 IncA protein Es2 PF09751.7 001129792.2_34224001_1 - 5.7e-81 273.3 13.1 5.7e-81 273.3 13.1 2.1 2 0 0 2 2 2 1 Nuclear protein Es2 Ribosomal_L22 PF00237.17 001297694.1_16822001_1 - 6.5e-38 129.2 0.6 7.9e-38 128.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Ribosomal_S2 PF00318.18 001329186.1_16822001_1 - 1.4e-25 89.7 0.0 4e-14 52.3 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.3 001329186.1_16822001_1 - 7.4e-11 43.1 16.5 1.3e-10 42.3 16.5 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus dsrm PF00035.24 001204727.1_03229001_2 - 2.8e-43 146.3 4.8 1.1e-10 41.9 0.0 6.4 6 0 0 6 6 6 4 Double-stranded RNA binding motif Staufen_C PF16482.3 001204727.1_03229001_2 - 2.3e-09 37.3 0.0 2.3e-09 37.3 0.0 4.1 5 0 0 5 5 5 1 Staufen C-terminal domain DND1_DSRM PF14709.5 001204727.1_03229001_2 - 1.4e-05 25.1 0.8 0.043 13.9 0.0 4.5 5 0 0 5 5 5 1 double strand RNA binding domain from DEAD END PROTEIN 1 Homeobox PF00046.27 001115078.1_03126001_1 - 1.2e-20 72.9 5.4 2.1e-20 72.2 5.4 1.4 1 0 0 1 1 1 1 Homeobox domain SelP_N PF04592.12 001115078.1_03126001_1 - 0.58 9.4 13.2 1.1 8.4 13.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TPX2 PF06886.9 001115078.1_03126001_1 - 1.4 9.1 8.3 0.13 12.4 0.8 2.9 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) PRIMA1 PF16101.3 001115078.1_03126001_3 - 0.37 10.7 7.0 0.79 9.6 7.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 COesterase PF00135.26 001357083.1_19627001_1 - 5.5e-132 441.1 0.0 8.6e-132 440.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001357083.1_19627001_1 - 0.00019 21.2 0.1 0.00067 19.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold TMEM190 PF15431.4 001357083.1_19627001_1 - 0.052 13.6 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 190 COesterase PF00135.26 001357084.1_19627001_2 - 5.7e-132 441.1 0.0 8.9e-132 440.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001357084.1_19627001_2 - 0.0002 21.2 0.1 0.00068 19.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold TMEM190 PF15431.4 001357084.1_19627001_2 - 0.053 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 190 COesterase PF00135.26 001357082.1_19627001_2 - 5.9e-132 441.1 0.0 9.1e-132 440.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001357082.1_19627001_2 - 0.0002 21.1 0.1 0.00068 19.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold TMEM190 PF15431.4 001357082.1_19627001_2 - 0.054 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 190 TPR_12 PF13424.4 214573.1_49426001_3 - 7.3e-70 231.1 24.9 2.1e-21 75.9 0.6 5.4 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.4 214573.1_49426001_3 - 6.2e-61 200.6 13.5 1.3e-15 56.6 0.0 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.4 214573.1_49426001_3 - 4.7e-30 101.2 14.2 7.4e-06 25.5 0.1 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.26 214573.1_49426001_3 - 5.4e-24 82.8 33.1 2.1e-07 30.3 0.5 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.15 214573.1_49426001_3 - 1.1e-14 53.1 31.0 0.0011 18.8 0.4 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.4 214573.1_49426001_3 - 4.9e-11 41.8 25.4 0.0023 17.9 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.4 214573.1_49426001_3 - 1.4e-09 37.6 7.7 0.086 13.1 0.7 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.4 214573.1_49426001_3 - 1.3e-08 34.8 9.1 4.1 8.4 0.2 6.5 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.4 214573.1_49426001_3 - 5e-08 33.4 13.3 0.037 14.6 0.6 5.5 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.4 214573.1_49426001_3 - 6.7e-08 32.8 12.1 0.0012 19.2 0.7 4.2 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_4 PF07721.12 214573.1_49426001_3 - 1.4e-05 25.2 0.0 7.9 7.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.5 214573.1_49426001_3 - 2.8e-05 24.1 11.0 0.1 12.7 0.6 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 NUDE_C PF04880.11 214573.1_49426001_3 - 0.0071 16.7 0.3 0.0071 16.7 0.3 2.0 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region JIP_LZII PF16471.3 214573.1_49426001_3 - 0.0095 16.0 2.4 0.0095 16.0 2.4 3.1 3 0 0 3 3 3 1 JNK-interacting protein leucine zipper II PPR PF01535.18 214573.1_49426001_3 - 0.012 15.7 1.2 6.1 7.2 0.0 4.1 5 0 0 5 5 3 0 PPR repeat DUF2225 PF09986.7 214573.1_49426001_3 - 0.018 14.7 1.7 1.5 8.4 0.8 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ADIP PF11559.6 214573.1_49426001_3 - 0.031 14.3 3.6 0.12 12.4 3.6 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF627 PF04781.10 214573.1_49426001_3 - 0.19 11.7 4.7 6.9 6.6 0.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF627) SOGA PF11365.6 214573.1_49426001_3 - 0.24 12.4 5.1 0.37 11.8 2.6 2.7 2 0 0 2 2 1 0 Protein SOGA GAS PF13851.4 214573.1_49426001_3 - 0.36 10.1 13.9 0.87 8.8 0.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.10 214573.1_49426001_3 - 0.92 8.7 8.2 1.8 7.7 8.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 BST2 PF16716.3 214573.1_49426001_3 - 0.94 10.0 7.1 1.5 9.3 2.0 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 TPR_3 PF07720.10 214573.1_49426001_3 - 1.1 9.2 15.7 3.1 7.8 0.5 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat IncA PF04156.12 214573.1_49426001_3 - 2.3 7.8 7.2 1.3 8.6 4.7 1.7 1 1 0 1 1 1 0 IncA protein Cnn_1N PF07989.9 214573.1_49426001_3 - 7.3 6.7 7.8 0.55 10.3 1.9 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Attractin PF08037.9 001204633.1_03222001_1 - 3e-35 119.9 10.7 4.5e-35 119.3 10.7 1.3 1 0 0 1 1 1 1 Attractin family zf-H2C2_2 PF13465.4 001252424.1_03124001_1 - 1.2e-31 107.5 40.1 3.3e-09 36.6 0.1 5.6 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.24 001252424.1_03124001_1 - 9.3e-16 57.2 51.8 0.00052 20.2 8.1 5.8 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001252424.1_03124001_1 - 2.1e-14 52.9 44.9 0.0074 16.9 0.1 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001252424.1_03124001_1 - 4.4e-12 45.8 23.6 0.0021 18.2 0.1 5.5 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001252424.1_03124001_1 - 2.7e-07 30.6 41.4 0.0049 17.1 0.3 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.4 001252424.1_03124001_1 - 0.0019 17.7 4.2 0.0019 17.7 4.2 5.9 6 2 0 6 6 4 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.4 001252424.1_03124001_1 - 0.0085 15.9 35.2 0.027 14.3 3.0 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HE PF16278.3 001252424.1_03124001_1 - 0.15 12.4 0.2 0.15 12.4 0.2 5.4 1 1 4 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.3 001252424.1_03124001_1 - 0.18 12.4 11.2 4 8.1 0.8 3.1 1 1 1 2 2 2 0 zinc-ribbon family HypA PF01155.17 001252424.1_03124001_1 - 0.2 11.6 11.8 1 9.3 1.1 2.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.10 001252424.1_03124001_1 - 0.82 9.6 15.7 0.25 11.3 2.2 3.5 1 1 3 4 4 4 0 zinc-ribbons zf-C2H2_8 PF15909.3 001252424.1_03124001_1 - 1.8 8.8 27.1 1.7 8.8 10.8 3.5 2 1 3 5 5 4 0 C2H2-type zinc ribbon GAGA PF09237.9 001252424.1_03124001_1 - 1.8 8.3 16.0 1.8 8.3 1.9 4.1 1 1 3 4 4 4 0 GAGA factor AJAP1_PANP_C PF15298.4 001252424.1_03124001_1 - 2.5 8.1 16.0 5.4 7.0 7.7 2.4 2 0 0 2 2 2 0 AJAP1/PANP C-terminus C1_4 PF07975.10 001252424.1_03124001_1 - 4.9 7.4 19.1 0.85 9.8 3.6 4.0 1 1 1 3 3 3 0 TFIIH C1-like domain Myc_N PF01056.16 001252424.1_03124001_1 - 5.9 6.5 13.7 0.18 11.5 2.0 2.5 2 1 1 3 3 3 0 Myc amino-terminal region zinc_ribbon_9 PF14369.4 001252424.1_03124001_1 - 8 6.7 11.9 11 6.2 0.0 4.1 5 0 0 5 5 4 0 zinc-ribbon zf-RING_7 PF02591.13 001252424.1_03124001_1 - 9.1 6.4 8.8 77 3.5 0.1 4.4 4 0 0 4 4 4 0 C4-type zinc ribbon domain Mucin PF01456.15 001252424.1_03124001_1 - 9.7 6.0 25.8 2.3 8.0 4.1 2.9 3 0 0 3 3 3 0 Mucin-like glycoprotein WD40 PF00400.30 001287799.1_26523001_3 - 1.2e-47 158.7 24.8 2.5e-08 34.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001287799.1_26523001_3 - 6e-09 36.0 2.0 0.095 12.9 0.1 4.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001287799.1_26523001_3 - 0.00048 19.1 0.2 0.58 8.9 0.0 3.7 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.3 001287799.1_26523001_3 - 0.021 14.1 0.0 6.1 5.9 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Nup160 PF11715.6 001287799.1_26523001_3 - 0.021 13.3 10.8 0.42 9.0 0.2 4.3 2 1 4 6 6 6 0 Nucleoporin Nup120/160 PD40 PF07676.10 001287799.1_26523001_3 - 0.085 12.7 0.0 19 5.2 0.0 3.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_C PF00034.19 001177490.1_03123001_1 - 1.8e-12 48.1 0.0 2.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.4 001177490.1_03123001_1 - 1.3e-06 28.5 1.9 4.6e-06 26.7 1.9 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.4 001177490.1_03123001_1 - 0.018 14.6 1.3 0.057 13.0 1.3 1.7 1 1 0 1 1 1 0 Cytochrome c-550 domain RRM_1 PF00076.20 001279407.1_10523001_2 - 1.3e-42 143.3 0.0 4e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001279407.1_10523001_2 - 2.7e-09 36.5 0.0 3.9e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001279407.1_10523001_2 - 0.0015 18.2 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif PHM7_cyt PF14703.4 001279407.1_10523001_2 - 0.0036 17.4 0.1 0.2 11.8 0.0 3.1 2 2 2 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.3 001279407.1_10523001_2 - 0.054 13.5 0.0 5.5 7.0 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif Vitellogenin_N PF01347.20 001304585.1_48729001_1 - 2.4e-162 541.4 16.3 2.4e-162 541.4 16.3 2.2 2 0 0 2 2 2 1 Lipoprotein amino terminal region VWD PF00094.23 001304585.1_48729001_1 - 8.2e-19 68.3 0.5 8.2e-19 68.3 0.5 3.0 3 0 0 3 3 3 1 von Willebrand factor type D domain DUF1943 PF09172.9 001304585.1_48729001_1 - 4.5e-13 49.0 1.2 4.5e-13 49.0 1.2 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1943) DNA_processg_A PF02481.13 001304585.1_48729001_1 - 0.011 14.9 0.0 0.03 13.4 0.0 1.7 1 0 0 1 1 1 0 DNA recombination-mediator protein A DUF3446 PF11928.6 001304585.1_48729001_1 - 0.47 10.7 7.7 0.79 9.9 4.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Neur_chan_memb PF02932.14 001305119.1_33324001_3 - 1.4e-52 179.0 0.0 1.9e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.21 001305119.1_33324001_3 - 1.6e-49 168.2 0.0 2.6e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Peptidase_C21 PF05381.10 001305119.1_33324001_3 - 0.12 12.6 1.0 0.46 10.7 0.2 2.2 2 0 0 2 2 2 0 Tymovirus endopeptidase Vitellogenin_N PF01347.20 001304584.1_48729001_3 - 8.3e-161 536.4 27.0 2.6e-160 534.7 27.0 1.8 1 1 0 1 1 1 1 Lipoprotein amino terminal region VWD PF00094.23 001304584.1_48729001_3 - 5.5e-17 62.3 1.1 5.5e-17 62.3 1.1 3.4 4 0 0 4 4 4 1 von Willebrand factor type D domain SPX PF03105.17 001304584.1_48729001_3 - 1.6e-05 24.9 9.5 1.6e-05 24.9 9.5 2.6 3 0 0 3 3 3 1 SPX domain Miga PF10265.7 001304584.1_48729001_3 - 0.13 11.1 12.5 0.14 10.9 10.4 2.1 2 0 0 2 2 2 0 Mitoguardin Tmemb_cc2 PF10267.7 001304584.1_48729001_3 - 0.84 8.6 17.0 0.04 12.9 9.2 2.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Gti1_Pac2 PF09729.7 001304584.1_48729001_3 - 1.2 9.0 19.5 2 8.3 8.9 3.8 3 0 0 3 3 3 0 Gti1/Pac2 family NAM-associated PF14303.4 001304584.1_48729001_3 - 1.2 9.6 13.7 0.13 12.8 6.7 2.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain FAM76 PF16046.3 001304584.1_48729001_3 - 4.7 6.3 19.0 1.1 8.4 10.3 2.5 2 0 0 2 2 2 0 FAM76 protein Macoilin PF09726.7 001304584.1_48729001_3 - 5.1 5.4 34.6 0.0022 16.5 14.1 3.2 3 0 0 3 3 3 0 Transmembrane protein DDHD PF02862.15 001304584.1_48729001_3 - 8.1 6.4 19.1 0.67 9.9 7.1 3.4 3 0 0 3 3 3 0 DDHD domain DUF4228 PF14009.4 001304584.1_48729001_3 - 9.1 6.6 13.2 3.1 8.1 6.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CAP PF00188.24 001304591.1_48722001_1 - 1.5e-23 83.8 0.6 1.5e-23 83.8 0.6 1.4 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Kelch_1 PF01344.23 001314151.1_28527001_1 - 2.2e-73 241.5 9.5 9.3e-13 47.4 0.0 12.4 12 0 0 12 12 12 10 Kelch motif Kelch_6 PF13964.4 001314151.1_28527001_1 - 4.8e-50 166.2 7.5 2.8e-05 24.1 0.0 12.1 4 2 8 12 12 12 11 Kelch motif Kelch_3 PF13415.4 001314151.1_28527001_1 - 1.5e-40 136.6 0.6 0.00012 22.1 0.0 11.4 12 0 0 12 12 12 7 Galactose oxidase, central domain Kelch_4 PF13418.4 001314151.1_28527001_1 - 1e-38 130.9 1.4 8.7e-06 25.5 0.0 8.8 7 2 2 9 9 9 7 Galactose oxidase, central domain Kelch_5 PF13854.4 001314151.1_28527001_1 - 1.7e-33 113.9 6.2 0.00027 20.7 0.0 11.3 11 0 0 11 11 11 8 Kelch motif Kelch_2 PF07646.13 001314151.1_28527001_1 - 3.2e-29 99.6 13.5 0.0016 18.2 0.0 11.9 11 1 0 11 11 11 9 Kelch motif IQ PF00612.25 001314151.1_28527001_1 - 0.12 12.1 0.5 0.36 10.6 0.5 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Defensin_2 PF01097.16 001311253.1_49321001_1 - 9.3e-14 50.9 6.0 9.3e-14 50.9 6.0 1.7 2 0 0 2 2 2 1 Arthropod defensin Gamma-thionin PF00304.18 001311253.1_49321001_1 - 0.0048 17.0 4.0 0.0078 16.3 4.0 1.3 1 0 0 1 1 1 1 Gamma-thionin family ATP-gua_Ptrans PF00217.17 001314084.1_28524001_2 - 7.1e-102 340.1 0.0 9.5e-102 339.6 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.13 001314084.1_28524001_2 - 3.2e-33 113.8 0.0 6.3e-32 109.7 0.0 2.3 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain NPA PF16469.3 001314084.1_28524001_2 - 0.45 11.1 2.4 19 5.8 0.0 3.4 4 0 0 4 4 4 0 Nematode polyprotein allergen ABA-1 adh_short PF00106.23 001315629.1_05022001_1 - 1.1e-39 135.8 0.1 1.3e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001315629.1_05022001_1 - 1.2e-21 77.2 0.0 1.8e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.17 001315629.1_05022001_1 - 6.1e-07 28.6 0.1 8.4e-07 28.1 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.8 001315629.1_05022001_1 - 2.5e-05 24.1 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001315629.1_05022001_1 - 0.00037 19.9 0.1 0.00072 18.9 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001315629.1_05022001_1 - 0.0012 18.1 0.1 0.0017 17.6 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.13 001315629.1_05022001_1 - 0.0043 16.1 0.1 0.0076 15.3 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF3446 PF11928.6 001315629.1_05022001_2 - 0.083 13.1 5.5 0.19 11.9 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) GST_N_3 PF13417.4 001308997.1_33322001_1 - 2.8e-14 53.1 0.0 4.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001308997.1_33322001_1 - 6.6e-12 45.5 0.2 2e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001308997.1_33322001_1 - 1.3e-07 31.7 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001308997.1_33322001_1 - 3.5e-07 30.2 0.1 6.1e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001308997.1_33322001_1 - 1.1e-05 25.4 0.2 2.2e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001308997.1_33322001_1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CAP PF00188.24 001323336.1_43422001_1 - 1.5e-21 77.4 2.8 2.5e-21 76.7 2.8 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Apyrase PF06079.9 001316700.2_12323001_1 - 1.1e-116 389.0 11.2 1.4e-116 388.7 11.2 1.0 1 0 0 1 1 1 1 Apyrase DUF1609 PF07753.9 001316700.2_12323001_1 - 0.066 12.6 1.1 0.12 11.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Lig_chan PF00060.24 152249.1_00825120_2 - 0.00066 19.4 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 152249.1_00825120_2 - 0.036 14.1 0.0 0.081 13.0 0.0 1.6 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan-Glu_bd PF10613.7 001358197.1_00827001_3 - 1.1e-07 31.9 0.0 3.1e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.24 001358197.1_00827001_3 - 0.00013 21.7 0.1 0.0012 18.6 0.0 2.5 3 0 0 3 3 3 1 Ligand-gated ion channel SBP_bac_3 PF00497.18 001358197.1_00827001_3 - 0.0065 15.8 0.0 0.042 13.1 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF1480 PF07351.11 001358199.1_00824001_1 - 0.039 14.1 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) 7tm_6 PF02949.18 001358199.1_00824001_2 - 5.3e-07 28.9 14.1 9.9e-07 28.0 14.1 1.5 1 0 0 1 1 1 1 7tm Odorant receptor DUF1959 PF09218.8 001358199.1_00824001_2 - 0.032 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) Lig_chan PF00060.24 001358151.1_00826001_1 - 1.9e-12 47.1 0.0 3.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001358151.1_00826001_1 - 6.7e-07 29.4 0.1 1.5e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001358151.1_00826001_1 - 3.8e-05 23.1 0.0 6.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.24 001358142.1_00825001_3 - 1.3e-09 37.9 0.1 2.5e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.18 001358142.1_00825001_3 - 0.00025 20.4 0.0 0.001 18.4 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 7tm_6 PF02949.18 001358170.1_00827001_2 - 1.4e-17 63.6 9.3 3.5e-17 62.3 9.3 1.7 1 1 0 1 1 1 1 7tm Odorant receptor Lig_chan-Glu_bd PF10613.7 001358158.1_00825001_2 - 2.5e-05 24.3 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.24 001358158.1_00825001_2 - 0.00083 19.1 0.0 0.0022 17.7 0.0 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel 7tm_7 PF08395.10 001358226.1_00824001_3 - 1.1e-16 60.9 41.2 2e-16 60.0 41.2 1.4 1 0 0 1 1 1 1 7tm Chemosensory receptor Lig_chan PF00060.24 001358250.1_00828001_1 - 5.8e-45 152.6 0.2 5.8e-45 152.6 0.2 2.2 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001358250.1_00828001_1 - 1.2e-25 89.8 0.1 3.6e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001358250.1_00828001_1 - 3.3e-16 59.3 0.0 1e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CcmE PF03100.13 001358250.1_00828001_1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 CcmE Ion_trans_2 PF07885.14 001358250.1_00828001_1 - 0.17 11.7 2.6 1.4 8.8 2.6 2.7 1 1 0 1 1 1 0 Ion channel Trehalose_recp PF06151.11 001358218.1_00824001_3 - 1.8e-96 323.2 19.1 2.6e-96 322.6 19.1 1.1 1 0 0 1 1 1 1 Trehalose receptor 7tm_7 PF08395.10 001358218.1_00824001_3 - 1.9e-09 37.1 30.1 8.5e-09 35.0 30.1 1.8 1 1 0 1 1 1 1 7tm Chemosensory receptor Lig_chan-Glu_bd PF10613.7 001358318.1_00824001_1 - 9.5e-09 35.3 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.24 001358318.1_00824001_1 - 7.9e-06 25.6 0.0 6.1e-05 22.8 0.0 2.5 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.18 001358318.1_00824001_1 - 0.0098 15.2 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 7tm_6 PF02949.18 001358339.1_00824001_3 - 9.6e-59 198.8 14.1 1.4e-58 198.3 14.1 1.2 1 0 0 1 1 1 1 7tm Odorant receptor Goodbye PF17109.3 001358339.1_00824001_3 - 0.16 12.3 2.3 0.43 10.9 0.8 2.0 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain DUF4363 PF14276.4 001358339.1_00824001_3 - 0.45 10.4 4.0 7.3 6.5 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) Lig_chan-Glu_bd PF10613.7 001358326.1_00824001_3 - 2.1e-07 31.0 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.24 001358326.1_00824001_3 - 0.0018 18.0 0.3 0.0029 17.3 0.3 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan PF00060.24 152265.1_00824120_3 - 7e-06 25.8 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.18 152265.1_00824120_3 - 0.005 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Y_Y_Y PF07495.11 152265.1_00824120_3 - 0.12 12.2 0.2 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Y_Y_Y domain Lig_chan PF00060.24 152392.1_00824120_1 - 0.053 13.2 4.8 2.6 7.8 4.3 2.8 1 1 0 1 1 1 0 Ligand-gated ion channel HSP70 PF00012.18 001204652.1_03225001_3 - 4.3e-266 883.7 13.1 4.9e-266 883.5 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001204652.1_03225001_3 - 2.7e-18 65.7 0.6 1.1e-16 60.5 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.4 001204652.1_03225001_3 - 0.00094 19.4 6.3 0.16 12.2 0.1 3.5 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.16 001204652.1_03225001_3 - 0.012 14.7 1.2 0.021 13.9 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.14 001204652.1_03225001_3 - 0.027 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4624 PF15417.4 001204652.1_03225001_3 - 0.028 14.1 0.1 0.21 11.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4624) DDR PF08841.8 001204652.1_03225001_3 - 0.052 12.4 0.6 0.28 10.0 0.4 2.1 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain CENP-Q PF13094.4 001204652.1_03225001_3 - 0.24 11.4 7.2 3.8 7.5 2.7 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_23 PF13476.4 001204652.1_03225001_3 - 2.4 8.5 11.8 10 6.5 5.9 2.4 2 0 0 2 2 2 0 AAA domain FAD_binding_1 PF00667.18 001286889.1_33325001_1 - 3.2e-73 245.8 0.0 4.8e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.23 001286889.1_33325001_1 - 1.9e-34 118.8 0.2 3.4e-34 118.0 0.2 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.19 001286889.1_33325001_1 - 3.5e-17 62.9 0.0 9.9e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain 7tm_6 PF02949.18 001358379.1_00823001_3 - 1.5e-07 30.7 14.9 1.5e-07 30.7 14.9 1.8 1 1 1 2 2 2 1 7tm Odorant receptor Spem1 PF15670.3 001358422.1_00824001_2 - 0.093 12.1 0.1 0.093 12.1 0.1 2.0 2 0 0 2 2 2 0 Spermatid maturation protein 1 7tm_7 PF08395.10 001358463.1_00823001_1 - 5.2e-18 65.3 24.0 6.1e-18 65.0 24.0 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor LisH PF08513.9 001358463.1_00823001_1 - 0.51 10.3 2.1 1.4 8.9 2.1 1.8 1 0 0 1 1 1 0 LisH 7tm_6 PF02949.18 001358457.1_00824001_1 - 1.5e-57 195.0 17.5 2.3e-57 194.3 17.5 1.3 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 001358457.1_00824001_1 - 2.7e-06 26.7 30.8 7e-06 25.3 30.8 1.7 1 1 0 1 1 1 1 7tm Chemosensory receptor 7tm_7 PF08395.10 001358262.1_00823001_2 - 2.2e-20 73.1 28.6 2.5e-20 72.9 28.6 1.0 1 0 0 1 1 1 1 7tm Chemosensory receptor STIMATE PF12400.6 001358262.1_00823001_2 - 0.038 14.3 4.8 1.5 9.2 0.4 2.8 2 0 0 2 2 2 0 STIMATE family DUF1426 PF07234.9 001358262.1_00823001_2 - 7 6.7 7.3 0.79 9.8 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1426) 7tm_7 PF08395.10 001358097.1_00824001_1 - 8.1e-40 137.0 34.5 1e-39 136.7 34.5 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor B12-binding PF02310.17 152404.1_00824120_1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain 7tm_6 PF02949.18 152438.1_00823120_2 - 5.1e-06 25.6 16.7 7.5e-06 25.1 16.7 1.2 1 0 0 1 1 1 1 7tm Odorant receptor DUF2207 PF09972.7 152438.1_00823120_2 - 0.16 10.5 1.7 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Abi PF02517.14 001358713.1_00825001_1 - 0.36 11.1 2.3 1.2 9.5 2.3 1.9 1 0 0 1 1 1 0 CAAX protease self-immunity SBP_bac_3 PF00497.18 152443.1_00823120_1 - 0.09 12.1 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 7tm_6 PF02949.18 152440.1_00823120_3 - 1.4e-14 53.8 9.4 1.9e-14 53.3 9.4 1.1 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_6 PF02949.18 152511.1_00823120_1 - 1.2e-09 37.6 0.7 1.5e-09 37.2 0.7 1.1 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_6 PF02949.18 152511.1_00823120_3 - 2.8e-08 33.1 5.6 4.2e-08 32.5 5.6 1.2 1 0 0 1 1 1 1 7tm Odorant receptor End_beta_barrel PF12195.6 152510.1_00821120_1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase DUF3278 PF11683.6 152509.1_00823120_1 - 1.1 9.2 6.7 5.6 6.9 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) 7tm_7 PF08395.10 152433.1_00823120_1 - 7e-34 117.5 31.6 8.3e-34 117.3 31.6 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor TSP_C PF05735.10 152433.1_00823120_1 - 0.099 12.4 0.5 0.17 11.7 0.5 1.2 1 0 0 1 1 1 0 Thrombospondin C-terminal region Lig_chan PF00060.24 152517.1_00824120_2 - 1.5e-07 31.2 0.0 3.7e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 152517.1_00824120_2 - 0.0033 17.5 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site 7tm_6 PF02949.18 152439.1_00823120_1 - 5.8e-23 81.3 13.8 7.9e-23 80.9 13.8 1.1 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 152439.1_00823120_1 - 0.036 13.1 24.4 0.063 12.3 24.4 1.4 1 1 0 1 1 1 0 7tm Chemosensory receptor DUF2678 PF10856.6 152439.1_00823120_1 - 7.6 6.4 13.5 0.032 14.0 2.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) Myosin_head PF00063.19 001358920.1_00829001_1 - 2.4e-276 918.2 0.0 2.4e-276 918.2 0.0 3.0 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.17 001358920.1_00829001_1 - 2.8e-165 551.8 263.9 3.3e-165 551.6 263.9 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.17 001358920.1_00829001_1 - 3.5e-13 49.0 1.5 7.2e-13 48.0 1.5 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ERM PF00769.17 001358920.1_00829001_1 - 9e-05 22.3 53.0 0.00021 21.1 20.1 9.4 1 1 6 8 8 8 4 Ezrin/radixin/moesin family Reo_sigmaC PF04582.10 001358920.1_00829001_1 - 0.00015 21.1 59.9 0.011 15.0 0.6 9.0 1 1 5 9 9 9 5 Reovirus sigma C capsid protein IQ PF00612.25 001358920.1_00829001_1 - 0.002 17.6 0.3 0.0079 15.8 0.1 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Synaptobrevin PF00957.19 001358920.1_00829001_1 - 0.0038 16.8 1.0 0.0038 16.8 1.0 7.2 11 1 1 12 12 12 1 Synaptobrevin Syntaxin-6_N PF09177.9 001358920.1_00829001_1 - 0.0096 16.3 6.9 0.0096 16.3 6.9 13.8 1 1 10 11 11 11 1 Syntaxin 6, N-terminal 7tm_6 PF02949.18 152563.1_00824120_3 - 4.5e-20 71.8 18.0 6.4e-20 71.3 18.0 1.2 1 0 0 1 1 1 1 7tm Odorant receptor CNDH2_N PF06278.9 152563.1_00824120_3 - 0.054 13.6 1.4 0.093 12.8 0.5 1.8 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF2721 PF11026.6 152563.1_00824120_3 - 0.15 11.8 2.1 0.19 11.5 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) GST_N_3 PF13417.4 001358981.1_00822001_1 - 2.9e-15 56.3 0.0 5.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001358981.1_00822001_1 - 2.7e-12 46.7 0.0 4.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001358981.1_00822001_1 - 1.3e-08 34.9 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001358981.1_00822001_1 - 2e-08 34.2 0.0 3.5e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001358981.1_00822001_1 - 4.3e-08 33.1 0.0 8.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001358981.1_00822001_1 - 0.0017 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 001358981.1_00822001_1 - 0.0022 18.6 0.0 0.0055 17.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.7 001358981.1_00822001_1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein 7tm_6 PF02949.18 152561.1_00824120_1 - 2.2e-38 131.9 17.5 2e-24 86.1 3.1 2.3 2 0 0 2 2 2 2 7tm Odorant receptor Homeobox PF00046.27 001359031.1_00829001_1 - 1.1e-19 69.8 6.4 2.8e-19 68.5 6.4 1.8 1 0 0 1 1 1 1 Homeobox domain Lipase PF00151.17 001304581.1_48723001_1 - 6.2e-23 81.5 0.1 8.8e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_1 PF00561.18 001304581.1_48723001_1 - 0.031 13.8 0.1 0.063 12.8 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.10 001304581.1_48723001_1 - 0.08 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.12 001304581.1_48723001_1 - 0.088 12.2 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Actin PF00022.17 001314123.1_28524001_3 - 9.8e-150 498.5 0.0 2.7e-149 497.1 0.0 1.6 1 1 0 1 1 1 1 Actin S19 PF06756.9 001308405.1_10523001_1 - 5.9e-17 61.2 4.5 5.9e-17 61.2 4.5 2.9 3 1 0 3 3 3 1 Chorion protein S19 C-terminal Calreticulin PF00262.16 214478.2_49424001_1 - 1.4e-80 270.8 18.8 6e-58 196.3 6.8 2.2 1 1 1 2 2 2 2 Calreticulin family MDM10 PF12519.6 214478.2_49424001_1 - 0.065 12.0 1.3 0.093 11.4 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Smac_DIABLO PF09057.8 214478.2_49424001_1 - 1 8.5 3.5 1.8 7.8 3.5 1.3 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases E2F_CC-MB PF16421.3 001129815.1_49424001_2 - 1.5e-34 118.2 0.2 2.5e-34 117.5 0.2 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.18 001129815.1_49424001_2 - 2.2e-23 81.9 0.1 4.4e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.10 001129815.1_49424001_2 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RRM_1 PF00076.20 001098447.1_49424001_1 - 1.2e-81 268.4 5.4 3.7e-21 74.6 0.5 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.16 001098447.1_49424001_1 - 3.4e-28 97.5 3.6 5.7e-27 93.6 3.3 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.4 001098447.1_49424001_1 - 1.4e-07 31.0 1.5 0.82 9.1 0.0 4.7 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001098447.1_49424001_1 - 4.3e-06 26.6 0.1 3.3 7.8 0.1 5.2 4 2 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.4 001098447.1_49424001_1 - 4.9e-05 23.1 0.2 4.3 7.2 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.3 001098447.1_49424001_1 - 0.00013 21.6 0.0 3.7 7.3 0.0 4.2 4 0 0 4 4 4 1 Occluded RNA-recognition motif Limkain-b1 PF11608.6 001098447.1_49424001_1 - 0.00068 19.5 0.8 14 5.7 0.0 4.3 4 0 0 4 4 4 0 Limkain b1 SET_assoc PF11767.6 001098447.1_49424001_1 - 0.0024 17.4 0.1 12 5.5 0.0 4.1 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.9 001098447.1_49424001_1 - 0.0036 17.2 2.9 0.78 9.7 0.1 3.4 4 0 0 4 4 4 2 RNA binding motif OB_RNB PF08206.9 001098447.1_49424001_1 - 0.022 14.3 2.7 25 4.5 0.2 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain BRAP2 PF07576.10 001098447.1_49424001_1 - 0.068 13.3 0.3 1.7 8.8 0.1 2.7 3 0 0 3 3 2 0 BRCA1-associated protein 2 DUF4788 PF16032.3 001098447.1_49424001_1 - 0.084 11.7 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) DbpA PF03880.13 001098447.1_49424001_1 - 0.11 12.3 0.0 78 3.2 0.0 3.4 3 0 0 3 3 3 0 DbpA RNA binding domain CSD PF00313.20 001098447.1_49424001_1 - 0.23 11.2 2.6 5.9 6.7 0.1 3.5 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain PHM7_cyt PF14703.4 001098447.1_49424001_1 - 0.34 11.0 5.8 1e+02 2.9 0.0 5.3 4 1 2 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter Glyco_transf_29 PF00777.16 001126310.1_49422001_1 - 8.6e-59 199.0 0.0 1.2e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DpaA_N PF16924.3 001126310.1_49422001_1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain Ion_trans PF00520.29 001144977.1_49426001_1 - 9.6e-53 178.8 57.3 7.8e-33 113.6 26.3 2.2 2 0 0 2 2 2 2 Ion transport protein MIF4G_like_2 PF09090.9 059449.5_07625001_1 - 1.1e-51 175.7 9.3 1.1e-51 175.7 9.3 1.7 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.17 059449.5_07625001_1 - 4.3e-30 104.8 0.1 4.3e-30 104.8 0.1 2.5 2 1 0 2 2 2 1 MIF4G domain MIF4G_like PF09088.9 059449.5_07625001_1 - 4.3e-23 81.9 0.1 1.7e-21 76.7 0.2 2.6 1 1 1 2 2 2 1 MIF4G like DUF677 PF05055.10 059449.5_07625001_1 - 0.0011 17.8 6.6 0.0025 16.7 6.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF677) CENP-H PF05837.10 059449.5_07625001_1 - 0.46 10.8 14.0 0.063 13.6 6.6 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DASH_Spc19 PF08287.9 059449.5_07625001_1 - 0.77 9.5 9.5 2.6 7.8 9.5 1.9 1 0 0 1 1 1 0 Spc19 DUF342 PF03961.11 059449.5_07625001_1 - 1.9 6.9 7.4 3.3 6.1 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2120 PF09893.7 059449.5_07625001_1 - 2.1 8.3 9.0 3.3 7.7 6.6 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Bromodomain PF00439.23 001025837.3_07629001_1 - 7.6e-88 288.6 22.8 1.7e-18 66.3 0.1 6.5 6 0 0 6 6 6 6 Bromodomain BAH PF01426.16 001025837.3_07629001_1 - 1.2e-27 96.1 8.1 3.2e-16 59.1 0.3 3.7 3 0 0 3 3 3 2 BAH domain HMG_box PF00505.17 001025837.3_07629001_1 - 4.6e-13 49.2 0.3 2.9e-12 46.7 0.2 2.5 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001025837.3_07629001_1 - 2.1e-08 34.5 0.3 2.1e-08 34.5 0.3 2.5 2 0 0 2 2 2 1 HMG-box domain zf-C2H2_aberr PF17017.3 001025837.3_07629001_1 - 2.8e-05 24.2 0.8 8.5e-05 22.6 0.8 1.9 1 0 0 1 1 1 1 Aberrant zinc-finger HTH_31 PF13560.4 001025837.3_07629001_1 - 0.068 13.4 1.8 0.65 10.3 0.4 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Nic96 PF04097.12 131352.1_07626120_1 - 9.5e-30 103.5 0.0 2e-29 102.4 0.0 1.4 2 0 0 2 2 2 1 Nup93/Nic96 Nic96 PF04097.12 131352.1_07626120_3 - 2.6e-64 217.7 0.0 3.4e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Hormone_recep PF00104.28 062383.6_07623001_1 - 7.5e-29 100.7 0.2 1.1e-28 100.1 0.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 062383.6_07623001_1 - 4.3e-21 75.0 13.9 9.1e-21 74.0 13.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) MAP70 PF07058.9 062383.6_07623001_1 - 0.046 12.3 0.1 0.069 11.8 0.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 His_Phos_2 PF00328.20 023949.1_07623120_1 - 1.2e-25 90.6 0.0 3.2e-25 89.2 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.20 023949.1_07623120_2 - 4.6e-23 82.1 0.1 6.1e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) LRR_8 PF13855.4 065542.4_07624001_1 - 1.8e-39 133.2 42.7 2.6e-12 46.2 0.8 9.1 7 3 1 9 9 9 5 Leucine rich repeat LRR_4 PF12799.5 065542.4_07624001_1 - 3.8e-27 93.7 47.3 4e-06 26.9 5.2 11.0 7 5 5 14 14 14 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 065542.4_07624001_1 - 6.8e-05 22.3 5.4 0.56 9.6 0.1 4.4 4 0 0 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.31 065542.4_07624001_1 - 0.00016 21.5 56.1 1.6 9.3 0.1 15.2 15 4 1 16 16 16 2 Leucine Rich Repeat LRR_6 PF13516.4 065542.4_07624001_1 - 0.0072 16.2 43.8 8.3 6.6 0.1 13.7 17 0 0 17 17 17 1 Leucine Rich repeat DUF4134 PF13572.4 065542.4_07624001_1 - 0.17 12.1 0.2 0.31 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) 7tm_1 PF00001.19 066342.4_07623001_1 - 1.5e-23 83.3 29.7 6.9e-23 81.1 29.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ArfGap PF01412.16 001027665.2_07627001_1 - 1.8e-39 134.3 0.0 7.3e-39 132.3 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ras PF00071.20 001027665.2_07627001_1 - 6e-21 74.6 0.1 1.2e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.5 001027665.2_07627001_1 - 5.5e-09 36.4 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001027665.2_07627001_1 - 3.9e-08 33.6 0.1 1.1e-05 25.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH PF00169.27 001027665.2_07627001_1 - 8.1e-08 32.6 1.1 0.011 16.1 0.1 3.0 2 0 0 2 2 2 2 PH domain Ank PF00023.28 001027665.2_07627001_1 - 3.1e-06 27.3 0.1 1.2e-05 25.4 0.2 2.1 2 0 0 2 2 1 1 Ankyrin repeat Ank_3 PF13606.4 001027665.2_07627001_1 - 5.1e-05 23.2 0.0 0.039 14.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Roc PF08477.11 001027665.2_07627001_1 - 0.00021 21.4 0.0 0.00092 19.3 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_5 PF13857.4 001027665.2_07627001_1 - 0.00022 21.4 0.1 0.00047 20.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PH_11 PF15413.4 001027665.2_07627001_1 - 0.0013 19.0 0.6 0.27 11.5 0.2 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain Arf PF00025.19 001027665.2_07627001_1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001027665.2_07627001_1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Chitin_synth_1 PF01644.15 001027665.2_07627001_1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Chitin synthase EF-hand_8 PF13833.4 001027498.4_07621001_1 - 4.7e-14 51.7 2.7 1.3e-09 37.6 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.4 001027498.4_07621001_1 - 7.2e-11 41.0 0.3 0.00043 19.9 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.30 001027498.4_07621001_1 - 8.2e-08 31.1 0.6 0.0062 15.9 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.4 001027498.4_07621001_1 - 2e-07 31.2 0.0 0.0056 17.0 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.4 001027498.4_07621001_1 - 0.0045 17.2 0.0 2.6 8.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain KRTAP PF11759.6 052144.1_07621120_2 - 4 7.9 21.2 1.8e+02 2.6 21.2 2.1 1 1 0 1 1 1 0 Keratin-associated matrix SET PF00856.26 171271.3_07621001_1 - 2.3e-21 76.8 0.2 7.9e-20 71.8 0.2 2.0 1 1 0 1 1 1 1 SET domain zf-C4 PF00105.16 171271.3_07621001_1 - 0.001 19.3 4.4 0.024 14.9 0.5 2.3 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Gal-bind_lectin PF00337.20 068090.1_07622001_1 - 1.7e-20 72.8 0.1 2.5e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin DUF3450 PF11932.6 069909.5_07625001_1 - 0.0037 16.4 10.9 0.0062 15.7 10.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) IncA PF04156.12 069909.5_07625001_1 - 0.4 10.3 20.3 4 7.1 21.0 2.0 1 1 0 1 1 1 0 IncA protein DUF724 PF05266.12 069909.5_07625001_1 - 0.92 9.2 15.4 2.5 7.8 15.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CENP-H PF05837.10 069909.5_07625001_1 - 4.8 7.5 18.8 3.1 8.1 15.8 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Apis_Csd PF11671.6 054790.1_07621120_3 - 0.055 13.4 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein DUF1265 PF06887.12 131623.1_07623120_2 - 2.3e-19 68.9 2.2 4.9e-19 67.9 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1265) Meis_PKNOX_N PF16493.3 001028488.3_07625001_1 - 0.083 13.1 0.2 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 7TM_GPCR_Srd PF10317.7 133597.1_07622120_1 - 3.3e-38 131.4 9.3 3.7e-38 131.3 9.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srh PF10318.7 133597.1_07622120_1 - 3.4e-09 36.0 5.9 3.8e-09 35.9 5.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Str PF10326.7 133597.1_07622120_1 - 7.3e-09 35.3 7.5 9.4e-09 34.9 7.5 1.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.7 133597.1_07622120_1 - 1.5e-08 34.2 4.4 1.8e-08 34.0 4.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Sri PF10327.7 133597.1_07622120_1 - 0.00091 18.4 4.2 0.0011 18.0 4.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Peptidase_S66 PF02016.13 133597.1_07622120_1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 LD-carboxypeptidase SMK-1 PF04802.13 138495.1_07627120_1 - 3.5e-56 190.0 2.5 5.7e-56 189.3 2.5 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 zf-C2H2 PF00096.24 001267395.1_07622001_1 - 5.3e-23 80.0 44.4 1e-06 28.7 2.5 5.8 5 1 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001267395.1_07622001_1 - 2.5e-20 71.8 42.8 1.5e-08 34.5 1.9 6.3 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_4 PF13894.4 001267395.1_07622001_1 - 6.9e-16 57.4 40.5 0.0004 20.8 1.8 5.7 5 1 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_11 PF16622.3 001267395.1_07622001_1 - 0.0002 20.9 18.0 0.2 11.3 0.5 4.6 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.4 001267395.1_07622001_1 - 0.00034 20.3 32.6 0.13 12.1 1.0 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.10 001267395.1_07622001_1 - 0.0014 18.8 23.6 0.0055 16.8 0.5 4.3 3 2 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.3 001267395.1_07622001_1 - 0.0015 18.7 16.1 0.0037 17.4 9.9 3.1 1 1 1 2 2 2 1 C2H2-type zinc ribbon NMD3 PF04981.11 001267395.1_07622001_1 - 0.015 14.6 2.0 0.015 14.6 2.0 1.9 2 1 0 2 2 2 0 NMD3 family zf-C2H2_9 PF16293.3 001267395.1_07622001_1 - 0.031 14.0 9.1 0.38 10.5 0.1 4.3 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.5 001267395.1_07622001_1 - 0.044 14.0 26.5 2 8.7 1.6 4.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.3 001267395.1_07622001_1 - 0.097 13.0 1.1 0.097 13.0 1.1 4.5 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CHCC PF10276.7 001267395.1_07622001_1 - 0.14 12.1 4.7 2 8.4 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger domain zf-C2HC_2 PF13913.4 001267395.1_07622001_1 - 0.45 10.3 0.1 0.45 10.3 0.1 4.6 5 0 0 5 5 4 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.3 001267395.1_07622001_1 - 1.3 9.7 15.8 0.72 10.5 4.5 2.9 1 1 1 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.8 001267395.1_07622001_1 - 4.1 7.5 18.4 9.6 6.3 3.1 4.4 3 2 1 4 4 4 0 Zinc ribbon domain zf-C2H2_jaz PF12171.6 001267395.1_07622001_1 - 9.5 6.5 28.1 7.8 6.8 0.3 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Not1 PF04054.13 066115.5_07629001_1 - 1.6e-127 425.3 4.5 1.6e-127 425.3 4.5 2.2 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.3 066115.5_07629001_1 - 7.1e-81 270.7 5.7 7.1e-81 270.7 5.7 2.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.3 066115.5_07629001_1 - 1e-53 181.2 0.1 3.5e-53 179.5 0.1 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.5 066115.5_07629001_1 - 1.1e-42 145.4 5.9 4.3e-42 143.4 5.9 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.3 066115.5_07629001_1 - 4.7e-29 101.2 0.3 1.6e-28 99.5 0.3 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF1778 PF08681.9 066115.5_07629001_1 - 0.032 14.0 0.5 0.12 12.2 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) Tup_N PF08581.8 001307126.1_07629001_1 - 0.00056 20.0 0.2 0.00056 20.0 0.2 21.3 19 5 5 25 25 25 3 Tup N-terminal Ion_trans PF00520.29 001028620.2_07624001_1 - 1.6e-38 132.2 8.6 2.7e-38 131.4 8.6 1.4 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001028620.2_07624001_1 - 5.2e-22 77.9 0.0 1.3e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001028620.2_07624001_1 - 4.8e-14 52.0 8.6 1.3e-13 50.5 8.6 1.8 1 0 0 1 1 1 1 Ion channel BTB_3 PF16017.3 001028620.2_07624001_1 - 0.0048 16.8 0.0 0.017 15.1 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain DUF423 PF04241.13 001028620.2_07624001_1 - 0.041 14.0 0.1 0.14 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF423) DUF3855 PF12967.5 001028620.2_07624001_1 - 0.12 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) PKD_channel PF08016.10 001028620.2_07624001_1 - 0.82 8.1 10.2 0.04 12.5 4.0 1.8 2 0 0 2 2 2 0 Polycystin cation channel WD40 PF00400.30 073770.4_07624001_1 - 1.9e-12 47.3 3.9 4.8e-05 23.9 0.2 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 073770.4_07624001_1 - 0.041 14.1 0.0 4.9 7.4 0.0 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans PF00520.29 001348594.1_07629001_1 - 4.1e-245 808.8 85.8 3.6e-66 222.7 21.8 4.1 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.3 001348594.1_07629001_1 - 1.4e-37 127.2 0.0 2.6e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.9 001348594.1_07629001_1 - 5.4e-30 103.4 0.1 1.4e-29 102.0 0.1 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.10 001348594.1_07629001_1 - 1.1e-06 27.4 35.9 5.4e-06 25.2 9.3 8.0 7 2 2 9 9 9 4 Polycystin cation channel Smr PF01713.19 074816.1_07622001_1 - 0.11 12.7 0.1 0.26 11.6 0.0 1.6 2 0 0 2 2 2 0 Smr domain FAM199X PF15814.3 066352.2_07621001_1 - 0.0068 15.4 2.9 0.0071 15.3 2.9 1.0 1 0 0 1 1 1 1 Protein family FAM199X Med3 PF11593.6 066352.2_07621001_1 - 5.5 5.9 11.3 5.9 5.8 11.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HI0933_like PF03486.12 062988.3_07624001_1 - 0.043 12.4 0.1 0.068 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein L27 PF02828.14 062988.3_07624001_1 - 0.053 13.1 0.0 8.7 6.1 0.0 2.5 2 0 0 2 2 2 0 L27 domain Rio2_N PF09202.9 001136333.1_07621001_1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Rio2, N-terminal Mitofilin PF09731.7 001267126.1_07622001_1 - 4.9 5.7 14.7 5.8 5.5 14.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Sod_Cu PF00080.18 001308888.1_14022001_1 - 3e-11 43.6 6.1 3.2e-11 43.4 5.2 1.5 1 1 1 2 2 2 1 Copper/zinc superoxide dismutase (SODC) SRCR PF00530.16 214599.1_49429001_2 - 5.4e-117 382.9 14.3 2.2e-28 98.6 0.1 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain TIL PF01826.15 214599.1_49429001_2 - 3e-45 152.1 67.9 2.6e-11 43.4 10.4 5.0 4 0 0 4 4 4 4 Trypsin Inhibitor like cysteine rich domain SRCR_2 PF15494.4 214599.1_49429001_2 - 1e-14 54.7 7.5 0.018 15.4 0.1 4.3 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Bacteroid_pep PF14406.4 214599.1_49429001_2 - 0.11 12.7 3.7 42 4.5 0.1 4.2 4 0 0 4 4 4 0 Ribosomally synthesized peptide in Bacteroidetes COesterase PF00135.26 001316707.1_12324001_1 - 3.8e-160 534.1 4.3 4.3e-160 533.9 4.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001316707.1_12324001_1 - 6.3e-08 32.6 0.0 2.3e-07 30.7 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Chitin_bind_4 PF00379.21 001172797.1_34222001_1 - 1e-16 61.0 2.3 1.6e-16 60.4 2.3 1.3 1 0 0 1 1 1 1 Insect cuticle protein 7tm_7 PF08395.10 001190522.1_34223001_1 - 5.2e-24 85.0 36.5 5.9e-24 84.8 36.5 1.0 1 0 0 1 1 1 1 7tm Chemosensory receptor Lipocalin_7 PF14651.4 001204490.1_03224001_2 - 0.0004 20.2 0.6 0.00062 19.6 0.6 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family C1q PF00386.19 214502.1_49424001_1 - 3.5e-12 46.5 0.3 8.5e-08 32.3 0.2 3.0 2 1 0 2 2 2 2 C1q domain Amino_oxidase PF01593.22 001204595.1_03226001_3 - 3.7e-29 102.2 0.1 6e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001204595.1_03226001_3 - 5.8e-11 42.4 0.1 1.3e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.12 001204595.1_03226001_3 - 0.0028 16.3 0.0 0.0041 15.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.5 001204595.1_03226001_3 - 0.011 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 001204595.1_03226001_3 - 0.049 12.7 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001204595.1_03226001_3 - 0.065 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.22 001204595.1_03226001_3 - 0.072 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.15 001204595.1_03226001_3 - 0.11 11.6 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family P2X_receptor PF00864.17 001204630.1_03223001_1 - 8.3e-138 459.3 0.1 1e-137 459.0 0.1 1.0 1 0 0 1 1 1 1 ATP P2X receptor Forkhead PF00250.16 001079542.1_49426001_2 - 8.2e-36 122.1 0.1 2.4e-35 120.6 0.1 1.9 1 0 0 1 1 1 1 Forkhead domain Forkhead_N PF08430.10 001079542.1_49426001_2 - 1.3e-17 64.6 55.7 1.3e-17 64.6 55.7 2.4 2 0 0 2 2 2 1 Forkhead N-terminal region HNF_C PF09354.8 001079542.1_49426001_2 - 1.9e-07 31.9 2.5 1.9e-07 31.9 2.5 4.9 3 1 0 3 3 3 1 HNF3 C-terminal domain Rib_hydrolayse PF02267.15 001256076.1_49423001_1 - 7.3e-68 228.4 0.0 8.5e-68 228.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase DUF383 PF04063.12 001256076.1_49423001_2 - 0.084 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF383) DUF3807 PF12720.5 001168132.1_46629001_2 - 0.31 11.2 14.2 0.15 12.2 12.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF4141 PF13605.4 001168132.1_46629001_2 - 1.4 8.1 5.8 11 5.3 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) YqfQ PF14181.4 001168132.1_46629001_2 - 6.8 6.7 12.7 9.4 6.3 12.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein 7tm_1 PF00001.19 001168132.1_46629001_3 - 2e-50 171.4 14.4 2e-50 171.4 14.4 2.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Forkhead PF00250.16 001164963.1_46624001_2 - 1.2e-33 115.1 0.0 1.9e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain P2X_receptor PF00864.17 001168169.1_46624001_3 - 5.4e-145 482.9 0.4 6.8e-145 482.6 0.4 1.0 1 0 0 1 1 1 1 ATP P2X receptor HLH PF00010.24 001171249.1_46623001_3 - 3e-19 68.6 0.2 5.1e-19 67.9 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Jun PF03957.11 001168030.1_46624001_2 - 4e-28 98.7 6.1 7.4e-28 97.9 6.1 1.3 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.19 001168030.1_46624001_2 - 1.3e-15 57.1 14.4 2.1e-15 56.4 14.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001168030.1_46624001_2 - 3.1e-06 27.1 14.4 1e-05 25.4 14.4 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001168030.1_46624001_2 - 4.7e-06 26.9 8.8 9.2e-06 26.0 8.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Jnk-SapK_ap_N PF09744.7 001168030.1_46624001_2 - 0.0036 17.4 5.4 0.0059 16.7 5.4 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ZapB PF06005.10 001168030.1_46624001_2 - 0.022 15.1 3.0 0.033 14.5 1.8 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Synaptobrevin PF00957.19 001168030.1_46624001_2 - 0.22 11.2 1.2 0.43 10.3 1.2 1.5 1 0 0 1 1 1 0 Synaptobrevin DivIC PF04977.13 001168030.1_46624001_2 - 2.2 8.0 4.0 2.4 7.8 2.7 1.7 1 1 0 1 1 1 0 Septum formation initiator CLTH PF10607.7 001162721.1_00723001_3 - 2e-33 115.2 0.6 2.8e-33 114.7 0.6 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Oxidored_q4 PF00507.17 001162721.1_00723001_3 - 1.4e-16 60.3 16.9 1.4e-16 60.3 16.9 2.7 2 1 1 3 3 3 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 LisH PF08513.9 001162721.1_00723001_3 - 8.9e-11 41.2 0.4 1.8e-09 37.1 0.4 2.6 2 0 0 2 2 2 1 LisH DUF1631 PF07793.9 001162721.1_00723001_3 - 0.05 11.9 0.1 0.069 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) GTP_cyclohydroI PF01227.20 001168090.1_46629001_2 - 4.2e-75 251.0 0.3 5.5e-75 250.6 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.4 001168090.1_46629001_2 - 0.0039 17.2 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein p450 PF00067.20 033331.1_34223120_3 - 8.6e-50 169.7 0.1 1.2e-49 169.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 HMG_box PF00505.17 001279288.1_01723001_1 - 8e-25 86.9 4.2 1.3e-24 86.2 4.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001279288.1_01723001_1 - 4.4e-09 36.7 1.8 1e-08 35.5 1.8 1.6 1 0 0 1 1 1 1 HMG-box domain IRK PF01007.18 001279290.1_01723001_1 - 4.7e-88 295.2 0.2 6.5e-88 294.7 0.2 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.14 001279290.1_01723001_1 - 0.75 9.7 14.4 2.6 8.0 14.2 2.0 1 1 0 1 1 1 0 Ion channel RGS PF00615.17 001279315.1_01725001_1 - 1.6e-17 63.7 2.0 1.6e-17 63.7 0.2 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DIX PF00778.15 001279315.1_01725001_1 - 5.5e-17 61.3 0.1 1.1e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 DIX domain PBP_GOBP PF01395.20 001040209.1_03122001_2 - 4.5e-14 52.5 1.3 5.8e-14 52.1 1.3 1.1 1 0 0 1 1 1 1 PBP/GOBP family Apis_Csd PF11671.6 001134828.1_03123001_1 - 2.7e-50 170.1 49.6 9e-35 119.7 17.3 5.3 3 3 1 4 4 4 2 Complementary sex determiner protein SDP_N PF12278.6 001134828.1_03123001_1 - 5.7e-38 130.0 15.9 5.7e-38 130.0 15.9 3.1 2 1 1 3 3 3 1 Sex determination protein N terminal Transformer PF06495.9 001134828.1_03123001_1 - 0.014 15.3 24.1 0.014 15.3 24.1 3.7 2 2 1 3 3 3 0 Fruit fly transformer protein Fz PF01392.20 001308628.1_01722001_1 - 2.2e-22 79.7 3.9 2.4e-22 79.6 3.1 1.4 2 0 0 2 2 2 1 Fz domain Glypican PF01153.17 001308628.1_01722001_1 - 0.1 11.3 1.0 0.13 10.9 1.0 1.1 1 0 0 1 1 1 0 Glypican IRK PF01007.18 001308621.1_01723001_1 - 6.2e-87 291.5 1.2 7.7e-87 291.2 1.2 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.14 001308621.1_01723001_1 - 0.02 14.7 10.6 0.061 13.2 10.5 1.9 1 1 0 1 1 1 0 Ion channel 7tm_1 PF00001.19 001304611.1_48725001_1 - 2.9e-55 187.3 19.0 6.3e-55 186.2 19.0 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001304611.1_48725001_1 - 3.1e-16 59.4 18.5 6.1e-16 58.4 18.5 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.7 001304611.1_48725001_1 - 2.5e-05 23.6 19.3 6.7e-05 22.2 18.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.4 001304611.1_48725001_1 - 0.0038 16.9 10.7 0.0072 16.0 10.7 1.4 1 0 0 1 1 1 1 Olfactory receptor MscL PF01741.16 001304611.1_48725001_1 - 0.078 13.2 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF1467 PF07330.10 001304611.1_48725001_1 - 7.9 6.4 11.5 0.095 12.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1467) Pkinase_Tyr PF07714.15 001309442.1_28629001_1 - 2.5e-51 174.3 0.3 3.2e-48 164.2 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase ANF_receptor PF01094.26 001309442.1_28629001_1 - 1.6e-47 162.2 2.6 2.2e-47 161.7 1.8 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region Pkinase PF00069.23 001309442.1_28629001_1 - 4.5e-27 94.9 0.0 4e-25 88.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Peripla_BP_6 PF13458.4 001309442.1_28629001_1 - 4.5e-17 62.6 0.0 1.7e-16 60.7 0.0 1.8 1 1 0 1 1 1 1 Periplasmic binding protein Thy1 PF02511.13 001309442.1_28629001_1 - 0.012 15.3 0.3 0.028 14.1 0.3 1.5 1 0 0 1 1 1 0 Thymidylate synthase complementing protein PEN-2 PF10251.7 001046740.1_06223001_2 - 1.6e-37 127.6 3.2 3.1e-37 126.7 3.2 1.5 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Pkinase PF00069.23 001309762.1_26523001_3 - 3.4e-61 206.8 0.0 4.2e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001309762.1_26523001_3 - 8.7e-31 107.0 0.0 1.2e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001309762.1_26523001_3 - 1.4e-06 27.7 0.1 2.2e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001309762.1_26523001_3 - 0.00028 20.2 0.0 0.00054 19.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001309762.1_26523001_3 - 0.00069 19.5 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.20 001309762.1_26523001_3 - 0.0011 18.5 0.2 0.0017 17.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family 7tm_1 PF00001.19 001309697.1_26523001_3 - 1.3e-18 67.1 18.9 1.8e-18 66.6 18.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Bcl-2 PF00452.17 001287769.1_26522001_1 - 1.2e-21 77.1 0.7 2.3e-21 76.1 0.7 1.5 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family DEK_C PF08766.9 001287769.1_26522001_1 - 0.26 11.1 1.4 0.55 10.1 0.0 2.2 3 0 0 3 3 3 0 DEK C terminal domain Innexin PF00876.16 001287770.1_26523001_1 - 4.8e-24 85.2 2.5 1.4e-23 83.6 2.5 1.6 1 1 0 1 1 1 1 Innexin Neurensin PF14927.4 001287770.1_26523001_1 - 0.019 14.6 0.1 0.074 12.6 0.1 1.9 2 0 0 2 2 2 0 Neurensin Shisa PF13908.4 001287770.1_26523001_1 - 0.064 13.3 0.5 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2207 PF09972.7 001287770.1_26523001_1 - 0.081 11.6 0.4 0.2 10.2 0.0 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.16 001287770.1_26523001_1 - 0.21 11.7 0.3 0.45 10.6 0.3 1.5 1 0 0 1 1 1 0 Glycophorin A DUF1700 PF08006.9 001287770.1_26523001_1 - 6.8 6.1 8.5 0.16 11.4 1.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) MH2 PF03166.12 001309742.1_26524001_1 - 4.4e-73 245.3 0.4 6.1e-73 244.9 0.4 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.14 001309742.1_26524001_1 - 7.9e-42 141.5 0.5 7.9e-42 141.5 0.5 1.8 2 0 0 2 2 2 1 MH1 domain IRF-3 PF10401.7 001309742.1_26524001_1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.4 001309742.1_26524001_1 - 0.14 12.0 0.2 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) TGF_beta PF00019.18 001309732.1_26523001_3 - 3.9e-16 59.7 7.1 9.1e-14 52.1 7.1 2.7 1 1 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 001309732.1_26523001_3 - 7.7e-05 22.4 1.0 0.00011 22.0 1.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide PDZ PF00595.22 001309750.1_26529001_2 - 1.9e-42 143.3 8.3 6.5e-15 55.1 0.7 3.5 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) ZU5 PF00791.18 001309750.1_26529001_2 - 6.4e-30 103.2 0.0 2e-29 101.7 0.0 1.9 1 0 0 1 1 1 1 ZU5 domain PDZ_2 PF13180.4 001309750.1_26529001_2 - 7.6e-17 61.3 2.5 0.00041 20.5 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.19 001309750.1_26529001_2 - 2e-06 27.5 0.0 5.2e-05 22.9 0.0 2.6 1 1 1 2 2 2 1 Guanylate kinase SH3_2 PF07653.15 001309750.1_26529001_2 - 0.00029 20.3 0.1 0.00098 18.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain FRG1 PF06229.10 001280830.1_26523001_3 - 8.6e-12 45.0 0.0 1.8e-05 24.4 0.0 3.0 1 1 1 3 3 3 3 FRG1-like domain Fascin PF06268.11 001280830.1_26523001_3 - 3.8e-08 33.4 0.0 0.02 15.0 0.0 3.0 2 1 0 2 2 2 2 Fascin domain RicinB_lectin_2 PF14200.4 001280830.1_26523001_3 - 0.00083 19.9 0.9 18 6.0 0.0 3.3 1 1 3 4 4 4 2 Ricin-type beta-trefoil lectin domain-like FGF PF00167.16 001280830.1_26523001_3 - 0.024 14.6 0.0 18 5.3 0.0 3.3 2 1 2 4 4 4 0 Fibroblast growth factor CBM_14 PF01607.22 001280892.1_26521001_1 - 3.4e-05 23.8 2.6 7.7e-05 22.7 2.6 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF2500 PF10694.7 001280892.1_26521001_1 - 0.0074 16.7 0.1 0.011 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2500) DUF2034 PF10356.7 001280892.1_26521001_1 - 0.011 15.1 0.3 0.015 14.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) CBM_14 PF01607.22 001309715.1_26521001_1 - 0.0017 18.4 2.8 0.0038 17.2 2.8 1.7 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain CPSase_L_D2 PF02786.15 001280939.1_26529001_3 - 5.2e-108 359.3 0.0 9.4e-81 270.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.20 001280939.1_26529001_3 - 1.4e-49 167.0 0.0 3e-49 165.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.19 001280939.1_26529001_3 - 1.3e-47 161.3 0.0 2.5e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.26 001280939.1_26529001_3 - 1.9e-46 158.1 0.0 4.5e-46 156.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.17 001280939.1_26529001_3 - 4.7e-39 133.4 0.1 1.1e-38 132.1 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.22 001280939.1_26529001_3 - 6.5e-34 117.2 0.1 1.6e-33 115.9 0.1 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.20 001280939.1_26529001_3 - 6.2e-19 67.8 0.0 3.7e-18 65.4 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.11 001280939.1_26529001_3 - 2.4e-13 50.0 0.7 4.2e-06 26.3 0.0 2.8 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.20 001280939.1_26529001_3 - 7.4e-13 48.3 0.0 6.3e-07 29.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.4 001280939.1_26529001_3 - 1.8e-11 43.2 0.0 0.00051 18.7 0.0 3.8 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Amidohydro_1 PF01979.18 001280939.1_26529001_3 - 5.5e-10 38.9 0.8 3.2e-09 36.4 0.1 2.5 2 1 0 2 2 2 1 Amidohydrolase family ATP-grasp_3 PF02655.12 001280939.1_26529001_3 - 5.5e-05 23.1 0.2 0.27 11.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.11 001280939.1_26529001_3 - 0.0027 17.4 0.1 0.0027 17.4 0.1 3.0 3 1 0 3 3 3 1 Peptidase C26 Collagen PF01391.16 001280895.1_26522001_1 - 1.9e-07 30.6 29.4 3e-07 29.9 29.4 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Sid-5 PF17204.1 001280895.1_26522001_2 - 0.082 12.9 3.2 0.079 13.0 1.4 1.9 1 1 1 2 2 2 0 Sid-5 family Pkinase_Tyr PF07714.15 001309728.1_26526001_1 - 1.2e-91 306.5 0.0 1.7e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001309728.1_26526001_1 - 6.2e-44 150.2 0.0 9.8e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.15 001309728.1_26526001_1 - 3.4e-15 55.8 0.0 9.9e-15 54.3 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001309728.1_26526001_1 - 1.3e-14 54.2 0.0 2.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) fn3 PF00041.19 001309728.1_26526001_1 - 1.4e-14 54.1 0.5 8.5e-09 35.5 0.1 3.6 4 0 0 4 4 4 2 Fibronectin type III domain EphA2_TM PF14575.4 001309728.1_26526001_1 - 2.5e-06 28.1 0.0 5.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ephrin_rec_like PF07699.11 001309728.1_26526001_1 - 0.00043 19.9 7.5 0.0026 17.4 4.1 2.5 2 0 0 2 2 2 1 Putative ephrin-receptor like RIO1 PF01163.20 001309728.1_26526001_1 - 0.0034 16.9 0.1 0.0077 15.7 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.12 001309728.1_26526001_1 - 0.016 14.4 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001309728.1_26526001_1 - 0.09 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cor1 PF04803.10 001309730.1_26522001_3 - 3.9e-39 133.7 19.5 6.7e-39 133.0 19.5 1.4 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region GLYCAM-1 PF05242.9 001309730.1_26522001_3 - 0.24 11.4 9.2 0.25 11.3 2.0 2.4 1 1 1 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Peptidase_C98 PF15499.4 001309730.1_26522001_3 - 7.1 5.9 10.6 4.1 6.7 5.1 2.1 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ets PF00178.20 001309667.1_26524001_2 - 4.1e-36 123.2 0.3 1.1e-35 121.8 0.3 1.8 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.14 001309667.1_26524001_2 - 2.8e-25 87.9 0.1 5.1e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pkinase_Tyr PF07714.15 001309753.1_26526001_1 - 7.5e-73 244.9 0.0 1.2e-72 244.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.14 001309753.1_26526001_1 - 3.6e-47 158.2 6.3 1.2e-12 47.6 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.4 001309753.1_26526001_1 - 4.1e-40 136.1 11.1 6.6e-10 39.3 0.9 5.4 5 0 0 5 5 5 5 Immunoglobulin domain Pkinase PF00069.23 001309753.1_26526001_1 - 5.9e-32 110.9 0.0 1.1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.4 001309753.1_26526001_1 - 1.2e-28 99.1 13.1 8.4e-06 25.9 1.8 5.7 5 1 0 5 5 5 5 Immunoglobulin domain ig PF00047.23 001309753.1_26526001_1 - 4.2e-27 94.0 6.6 4.2e-08 33.1 0.7 5.3 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.15 001309753.1_26526001_1 - 1.5e-16 60.4 6.1 3.4e-07 30.2 0.1 6.7 5 3 1 6 6 6 2 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001309753.1_26526001_1 - 3.5e-05 23.6 0.3 15 5.6 0.0 5.2 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 001309753.1_26526001_1 - 0.0011 19.0 2.8 0.42 10.7 0.0 4.8 6 0 0 6 6 6 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.10 001309753.1_26526001_1 - 0.0094 15.9 5.5 12 6.0 0.0 4.1 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.3 001309753.1_26526001_1 - 0.014 15.6 8.0 3.4 7.9 0.1 5.5 4 2 1 5 5 5 0 T-cell surface glycoprotein CD3 delta chain DUF2807 PF10988.6 001309753.1_26526001_1 - 0.09 12.4 0.3 0.18 11.4 0.3 1.5 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Kdo PF06293.12 001309753.1_26526001_1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ICAM_N PF03921.12 001309753.1_26526001_1 - 9.6 5.8 7.7 4.3 7.0 0.1 3.8 4 1 1 5 5 5 0 Intercellular adhesion molecule (ICAM), N-terminal domain TNFR_c6 PF00020.16 001309726.1_26522001_1 - 5.4e-11 42.6 26.0 4.2e-08 33.3 6.0 3.5 3 1 1 4 4 4 2 TNFR/NGFR cysteine-rich region Death PF00531.20 001309726.1_26522001_1 - 2.5e-09 37.0 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Death domain Ephrin_rec_like PF07699.11 001309726.1_26522001_1 - 0.0014 18.2 11.4 0.0014 18.2 11.4 3.4 2 1 2 4 4 4 2 Putative ephrin-receptor like ASC PF00858.22 001309727.1_26523001_1 - 2.2e-81 273.8 5.5 2.7e-81 273.5 5.5 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel CASP_C PF08172.10 001309705.1_26525001_3 - 1.4e-57 194.8 13.1 1.4e-57 194.8 13.1 4.1 2 1 1 3 3 3 1 CASP C terminal DUF2205 PF10224.7 001309705.1_26525001_3 - 0.0093 15.8 2.8 0.0093 15.8 2.8 5.0 4 1 1 5 5 5 1 Predicted coiled-coil protein (DUF2205) Calcyon PF06387.9 001309705.1_26525001_3 - 0.1 12.5 0.2 0.1 12.5 0.2 2.3 2 0 0 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) TruB_C_2 PF16198.3 001309705.1_26525001_3 - 0.14 12.2 0.9 8.6 6.5 0.3 2.9 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain Pkinase PF00069.23 001309681.1_26525001_1 - 1.2e-65 221.3 0.0 2.2e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001309681.1_26525001_1 - 1.7e-35 122.4 0.0 4.1e-35 121.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.20 001309681.1_26525001_1 - 1e-28 98.8 25.3 7.5e-16 57.6 8.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.28 001309681.1_26525001_1 - 9e-28 96.5 0.0 1.6e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.22 001309681.1_26525001_1 - 4.8e-06 27.0 2.6 1e-05 26.0 2.6 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.14 001309681.1_26525001_1 - 0.00046 20.3 16.8 0.015 15.5 5.5 2.5 2 0 0 2 2 2 2 C1 domain Kinase-like PF14531.4 001309681.1_26525001_1 - 0.0013 18.0 0.0 0.0027 16.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.4 001309681.1_26525001_1 - 0.0087 15.6 0.4 2.2 7.7 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.21 001309681.1_26525001_1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FYVE_2 PF02318.14 001309681.1_26525001_1 - 3.9 7.6 11.2 2.1 8.5 0.8 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.4 001309681.1_26525001_1 - 3.9 6.9 14.6 1.6 8.2 1.4 3.0 3 0 0 3 3 3 0 PHD-finger PHD PF00628.27 001309681.1_26525001_1 - 5.3 6.9 19.8 2.1 8.2 5.5 2.7 2 0 0 2 2 2 0 PHD-finger SDP_N PF12278.6 001310036.1_53125001_2 - 3.4e-87 290.1 15.9 3.4e-87 290.1 15.9 3.8 2 1 2 4 4 4 1 Sex determination protein N terminal Apis_Csd PF11671.6 001310036.1_53125001_2 - 5.1e-15 55.6 36.8 5.1e-15 55.6 36.8 3.9 2 2 1 3 3 3 1 Complementary sex determiner protein Apis_Csd PF11671.6 001289194.1_02923001_1 - 1.3e-49 167.8 51.4 1.6e-34 118.9 17.4 5.1 3 2 2 5 5 5 2 Complementary sex determiner protein SDP_N PF12278.6 001289194.1_02923001_1 - 5.6e-41 139.8 15.8 5.6e-41 139.8 15.8 3.0 2 1 1 3 3 3 1 Sex determination protein N terminal Transformer PF06495.9 001289194.1_02923001_1 - 0.00077 19.5 23.9 0.00077 19.5 23.9 3.4 2 1 1 3 3 3 1 Fruit fly transformer protein IFP_35_N PF07334.11 001289194.1_02923001_1 - 2.4 8.1 5.3 1.5 8.8 2.3 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Alpha-amylase PF00128.22 001289196.1_02924001_1 - 1.1e-96 324.3 0.5 1.9e-96 323.4 0.5 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Cyc-maltodext_C PF10438.7 001289196.1_02924001_1 - 8.8e-05 22.4 0.4 0.00027 20.9 0.4 1.8 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain Malt_amylase_C PF16657.3 001289196.1_02924001_1 - 0.00097 19.1 0.2 0.0031 17.5 0.2 1.9 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_42C PF08533.8 001289196.1_02924001_1 - 0.67 9.6 2.7 0.44 10.2 0.2 2.0 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain NumbF PF06311.10 001165002.1_46628001_3 - 7.4e-30 103.3 1.8 7.4e-30 103.3 1.8 2.6 3 0 0 3 3 3 1 NUMB domain PID PF00640.21 001165002.1_46628001_3 - 1.2e-24 86.8 0.0 2.5e-24 85.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.4 001165002.1_46628001_3 - 1.3e-05 25.0 0.1 2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.11 001165002.1_46628001_3 - 0.00029 20.9 0.0 0.00045 20.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Yippee-Mis18 PF03226.12 001184922.1_46624001_2 - 5e-11 42.6 0.6 7.9e-11 42.0 0.6 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Forkhead PF00250.16 001164965.1_46627001_3 - 6.3e-37 125.6 0.0 1.1e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Homeobox PF00046.27 001171210.1_46623001_3 - 7.1e-23 80.1 4.8 1.3e-22 79.2 4.8 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001171210.1_46623001_3 - 0.0025 17.5 0.2 0.0056 16.4 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.27 001168154.1_46623001_3 - 4.9e-24 83.8 2.7 9.5e-24 82.9 2.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001168154.1_46623001_3 - 0.0019 17.9 0.1 0.0048 16.6 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain OAR PF03826.15 001168154.1_46623001_3 - 0.0033 17.1 0.3 0.0076 15.9 0.3 1.5 1 0 0 1 1 1 1 OAR domain OAD_gamma PF04277.11 001164971.1_46627001_1 - 8.8 6.9 6.9 19 5.8 6.9 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain LIM PF00412.20 001164971.1_46627001_2 - 2.3e-31 107.7 20.6 2.8e-16 59.3 3.4 2.5 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.27 001164971.1_46627001_2 - 2e-18 65.8 2.6 4e-18 64.8 2.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001164971.1_46627001_2 - 9.5e-05 22.1 0.1 0.0002 21.1 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.6 001164971.1_46627001_2 - 0.032 13.6 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez NADH_oxidored PF08040.9 001184933.1_46622001_3 - 5.4e-15 54.7 0.3 9.2e-15 54.0 0.3 1.4 1 0 0 1 1 1 1 MNLL subunit Myc_N PF01056.16 001164972.1_46624001_2 - 1.4e-36 126.9 21.2 2.2e-27 96.7 1.1 3.8 1 1 3 4 4 4 3 Myc amino-terminal region HLH PF00010.24 001164972.1_46624001_2 - 1.1e-13 50.8 1.3 3.4e-13 49.2 1.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TFIIF_alpha PF05793.10 001164972.1_46624001_2 - 3.9 5.8 15.0 24 3.2 13.9 2.1 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase_Tyr PF07714.15 001164953.1_46627001_2 - 2.7e-101 338.1 0.0 4.3e-101 337.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.14 001164953.1_46627001_2 - 9.3e-44 147.3 0.0 5.5e-15 55.1 0.0 4.3 3 1 0 3 3 3 3 Immunoglobulin I-set domain Pkinase PF00069.23 001164953.1_46627001_2 - 9.4e-44 149.6 0.0 2.8e-43 148.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ig_3 PF13927.4 001164953.1_46627001_2 - 1.4e-36 124.8 0.0 7.8e-13 48.7 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.23 001164953.1_46627001_2 - 2.4e-26 91.6 0.0 1.7e-07 31.2 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001164953.1_46627001_2 - 1.7e-24 85.8 0.1 5e-10 39.5 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.15 001164953.1_46627001_2 - 3.8e-10 39.8 2.2 0.037 14.0 0.0 5.8 3 3 1 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.10 001164953.1_46627001_2 - 4.8e-10 39.2 0.0 0.00078 19.3 0.0 3.6 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.3 001164953.1_46627001_2 - 0.002 18.0 0.0 2.9 7.9 0.0 3.3 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain PRIMA1 PF16101.3 001164953.1_46627001_2 - 0.24 11.3 1.6 0.3 11.0 0.3 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 BAMBI PF06211.10 001164893.1_46623001_3 - 2.7e-18 66.0 4.9 6.6e-18 64.8 4.8 1.7 2 0 0 2 2 2 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.21 001164893.1_46623001_3 - 0.005 17.7 11.3 0.005 17.7 11.3 1.6 2 0 0 2 2 2 1 Activin types I and II receptor domain Fibrinogen_C PF00147.16 001168067.1_46624001_3 - 1.4e-66 224.3 2.6 1.9e-66 223.9 2.6 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain TGFb_propeptide PF00688.16 001184798.1_46624001_3 - 5.7e-30 104.7 0.0 8.1e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 001184798.1_46624001_3 - 6.1e-25 88.0 2.8 1.1e-24 87.2 2.8 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain HORMA PF02301.16 001168110.1_46627001_1 - 6.3e-07 29.1 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 HORMA domain VWC PF00093.16 001164999.1_46625001_2 - 9.8e-31 105.7 55.1 2.5e-13 50.0 9.7 4.7 4 0 0 4 4 4 3 von Willebrand factor type C domain Amnionless PF14828.4 001164999.1_46625001_2 - 0.00054 18.8 3.0 0.00054 18.8 3.0 3.3 2 1 0 3 3 3 2 Amnionless Ectoine_synth PF06339.10 001184850.1_46622001_3 - 1.9e-32 112.0 0.4 2.3e-25 89.1 0.2 2.1 2 0 0 2 2 2 2 Ectoine synthase Cupin_2 PF07883.9 001184850.1_46622001_3 - 0.0015 18.1 0.0 0.024 14.2 0.0 2.3 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.17 001184850.1_46622001_3 - 0.079 12.7 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 AraC-like ligand binding domain Eapp_C PF10238.7 001168121.1_46628001_2 - 0.2 11.6 10.5 0.36 10.8 10.5 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Myotub-related PF06602.12 001168121.1_46628001_3 - 3.1e-149 496.5 0.0 4.2e-149 496.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.18 001168121.1_46628001_3 - 2.5e-15 56.1 0.0 6.4e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 GRAM domain 3-PAP PF12578.6 001168121.1_46628001_3 - 0.0019 17.8 0.4 0.0081 15.8 0.3 2.1 2 0 0 2 2 2 1 Myotubularin-associated protein EHN PF06441.10 001168455.1_51224001_3 - 7.2e-31 106.5 0.1 1.5e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.18 001168455.1_51224001_3 - 2.1e-16 60.2 0.0 5.3e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001168455.1_51224001_3 - 0.011 16.3 0.0 0.024 15.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-C3HC4_3 PF13920.4 001142869.1_34224001_1 - 3e-10 39.7 15.8 3e-10 39.7 15.8 3.6 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001142869.1_34224001_1 - 0.0045 16.7 14.4 0.0045 16.7 14.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.19 001142869.1_34224001_1 - 0.01 15.8 13.1 0.01 15.8 13.1 3.3 2 2 0 2 2 2 0 FYVE zinc finger DUF4518 PF15008.4 001142869.1_34224001_1 - 0.015 14.4 0.1 0.056 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Armet PF10208.7 001142869.1_34224001_1 - 0.02 14.7 9.2 0.51 10.1 1.1 3.0 3 0 0 3 3 3 0 Degradation arginine-rich protein for mis-folding HeH PF12949.5 001142869.1_34224001_1 - 0.081 12.5 0.2 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 HeH/LEM domain Telomere_Sde2_2 PF13297.4 001142869.1_34224001_1 - 0.27 10.8 1.0 0.64 9.6 1.0 1.6 1 1 0 1 1 1 0 Telomere stability C-terminal Ank_4 PF13637.4 001161547.1_34222001_2 - 1.2e-23 83.0 2.6 2.6e-11 43.7 0.2 3.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.5 001161547.1_34222001_2 - 1.5e-19 70.2 0.0 5.2e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001161547.1_34222001_2 - 1.8e-18 66.2 0.8 5e-10 39.3 0.2 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.28 001161547.1_34222001_2 - 5.6e-17 61.2 1.9 9.1e-07 28.9 0.5 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.4 001161547.1_34222001_2 - 7.9e-16 56.4 0.4 3.8e-05 23.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat SH3_2 PF07653.15 001161547.1_34222001_2 - 2.9e-09 36.4 0.0 5.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 001161547.1_34222001_2 - 7.9e-09 35.1 0.1 2.1e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001161547.1_34222001_2 - 1.4e-08 34.0 0.1 1.4e-08 34.0 0.1 2.1 2 1 0 2 2 2 1 SH3 domain Neur_chan_LBD PF02931.21 001172555.1_34225001_2 - 4.3e-46 156.9 5.2 5.9e-46 156.5 5.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001172555.1_34225001_2 - 0.0001 22.3 9.8 0.00023 21.2 2.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region C1q PF00386.19 001161680.1_34226001_1 - 6.2e-06 26.3 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 C1q domain BTB PF00651.29 001164126.1_34225001_3 - 1.2e-22 80.1 0.1 2e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.24 001164126.1_34225001_3 - 0.034 14.5 0.5 0.034 14.5 0.5 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001164126.1_34225001_3 - 0.058 14.1 0.3 0.058 14.1 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.5 001164126.1_34225001_3 - 2 8.8 5.9 11 6.4 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PP-binding PF00550.23 001167851.1_34222001_1 - 2.6e-12 46.8 0.1 3.9e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Homeobox PF00046.27 001134925.1_34224001_1 - 1.8e-19 69.2 2.7 1.8e-19 69.2 2.7 2.3 2 0 0 2 2 2 1 Homeobox domain DUF2722 PF10846.6 001134925.1_34224001_1 - 0.08 11.7 44.0 0.027 13.3 12.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.11 001134925.1_34224001_3 - 0.092 12.6 16.5 0.13 12.1 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4700 PF15771.3 001134925.1_34224001_3 - 9.1 4.8 15.4 13 4.2 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4700) Trypsin PF00089.24 001172604.1_34223001_1 - 4.4e-52 176.9 0.0 5.9e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001172604.1_34223001_1 - 0.012 16.3 0.0 0.033 14.9 0.0 1.7 1 1 0 1 1 1 0 Trypsin-like peptidase domain DUF1986 PF09342.9 001172604.1_34223001_1 - 0.013 15.8 0.0 0.038 14.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Endothelin PF00322.15 001142859.1_34223001_2 - 1.9 8.1 8.2 0.33 10.5 4.0 2.0 2 0 0 2 2 2 0 Endothelin family CDK2AP PF09806.7 001142859.1_34223001_3 - 1.4e-15 57.9 1.0 3.2e-15 56.7 0.9 1.5 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein SUIM_assoc PF16619.3 001142859.1_34223001_3 - 0.027 14.5 4.9 0.047 13.7 4.9 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 p450 PF00067.20 001172545.1_34224001_3 - 5.4e-90 302.2 4.2 6.5e-90 301.9 4.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 SPK PF04435.16 001172545.1_34224001_3 - 0.018 15.3 0.1 0.07 13.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF545) p450 PF00067.20 001172530.1_34224001_3 - 6.2e-99 331.7 0.1 7e-99 331.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 NDUF_B6 PF09782.7 001172319.1_34222001_3 - 1.2e-43 148.8 0.2 1.4e-43 148.6 0.2 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Neur_chan_memb PF02932.14 001247956.1_34224001_1 - 6.8e-78 261.9 0.1 8.8e-78 261.5 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.21 001247956.1_34224001_1 - 4.2e-77 258.3 0.1 5.6e-77 257.9 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1765 PF08578.8 001247956.1_34224001_1 - 0.027 14.8 0.7 0.097 13.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) UCR_UQCRX_QCR9 PF05365.10 001167979.1_34222001_2 - 1.5e-24 85.6 2.5 2.2e-24 85.0 2.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Neuroparsin PF07327.9 001167724.1_34222001_1 - 4.5e-13 49.4 13.1 6.4e-13 48.9 13.1 1.2 1 0 0 1 1 1 1 Neuroparsin 7tm_6 PF02949.18 001190617.1_34223001_1 - 1.9e-24 86.2 8.7 2.6e-24 85.7 8.7 1.1 1 0 0 1 1 1 1 7tm Odorant receptor ATP-synt_F6 PF05511.9 001172346.1_34222001_3 - 8.2e-29 99.8 0.1 1.1e-28 99.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 Rad51 PF08423.9 001159341.1_34223001_3 - 4.9e-36 124.2 0.1 6.7e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.19 001159341.1_34223001_3 - 1.8e-05 24.2 0.1 0.00049 19.5 0.1 2.3 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.11 001159341.1_34223001_3 - 0.00032 20.0 0.0 0.00054 19.2 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.4 001159341.1_34223001_3 - 0.024 14.1 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain p450 PF00067.20 033333.1_34223120_1 - 5.8e-16 58.1 0.0 9.8e-12 44.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.20 033333.1_34223120_3 - 8e-19 67.6 0.0 1.5e-18 66.7 0.0 1.3 2 0 0 2 2 2 1 Cytochrome P450 Ribosomal_L28e PF01778.15 001297679.1_16821001_1 - 8.8e-30 103.6 2.3 8.8e-30 103.6 2.3 1.3 2 0 0 2 2 2 1 Ribosomal L28e protein family Mt_ATP-synt_D PF05873.10 001297695.1_16822001_1 - 4.8e-56 188.7 4.1 6.3e-56 188.4 4.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) CRA_rpt PF07046.9 001297695.1_16822001_1 - 0.053 13.6 0.9 0.11 12.5 0.9 1.5 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat DUF3271 PF11675.6 001297695.1_16822001_1 - 0.14 11.2 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) POPLD PF08170.10 001297695.1_16822001_1 - 0.37 11.1 2.9 1.2 9.4 0.1 2.6 3 0 0 3 3 3 0 POPLD (NUC188) domain T4_deiodinase PF00837.15 001174171.1_46627001_1 - 1.6e-19 70.0 0.0 3.4e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Iodothyronine deiodinase Peptidase_S8 PF00082.20 001204639.1_03225001_1 - 2.4e-50 171.4 1.8 3.2e-50 171.0 1.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.18 001204639.1_03225001_1 - 2.2e-24 85.2 0.2 3.8e-24 84.4 0.2 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.3 001204639.1_03225001_1 - 7.4e-21 74.6 1.9 1.4e-20 73.8 1.9 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain 7tm_1 PF00001.19 001204582.1_03224001_3 - 2.2e-76 256.5 3.6 2.2e-76 256.5 3.6 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001204582.1_03224001_3 - 1.7e-09 37.3 14.6 3.3e-06 26.6 13.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001204582.1_03224001_3 - 0.0052 16.4 12.0 0.028 14.0 6.0 2.6 3 0 0 3 3 3 2 Olfactory receptor Phage_holin_3_6 PF07332.9 001204582.1_03224001_3 - 0.17 11.8 8.3 5.5 6.9 0.0 3.5 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Gp_dh_C PF02800.18 001280826.1_03224001_1 - 2.3e-69 231.9 0.0 3.4e-69 231.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001280826.1_03224001_1 - 6.8e-36 122.5 0.2 1.8e-35 121.2 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain G-alpha PF00503.18 001204703.1_03223001_1 - 4.6e-120 400.9 5.9 5.3e-120 400.7 5.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001204703.1_03223001_1 - 1e-17 64.0 1.6 2.6e-13 49.7 0.5 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001204703.1_03223001_1 - 6.4e-06 25.6 3.7 0.00034 19.9 0.8 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.11 001204703.1_03223001_1 - 0.00011 22.3 0.7 0.36 10.9 0.1 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 001204703.1_03223001_1 - 0.021 14.3 2.8 0.75 9.2 0.8 2.6 2 1 0 2 2 2 0 Ras family TniB PF05621.9 001204703.1_03223001_1 - 0.03 13.4 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PROCN PF08083.9 001204703.1_03223001_1 - 0.066 11.8 0.0 0.17 10.4 0.0 1.6 2 0 0 2 2 2 0 PROCN (NUC071) domain AAA_29 PF13555.4 001204703.1_03223001_1 - 0.076 12.6 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NRN1 PF15056.4 001204669.1_03222001_3 - 0.0075 16.2 0.2 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 Neuritin protein family CPG4 PF15481.4 001204669.1_03222001_3 - 1.3 9.6 6.8 1.6 9.4 2.9 2.5 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 HEAT_EZ PF13513.4 001204674.1_03226001_1 - 3.8e-19 68.6 5.5 1.8e-11 44.1 0.0 8.1 8 1 1 9 9 9 2 HEAT-like repeat HEAT PF02985.20 001204674.1_03226001_1 - 2e-17 61.6 14.2 6.7e-06 25.8 0.0 8.9 9 0 0 9 9 9 3 HEAT repeat IBN_N PF03810.17 001204674.1_03226001_1 - 1.2e-09 37.9 4.3 4e-09 36.1 0.3 3.4 3 1 1 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.4 001204674.1_03226001_1 - 1e-08 35.3 3.7 0.00029 21.0 0.0 5.8 3 2 2 5 5 5 2 HEAT repeats Cnd1 PF12717.5 001204674.1_03226001_1 - 1.8e-06 27.9 4.6 3.9e-06 26.8 0.0 3.7 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.6 001204674.1_03226001_1 - 3.1e-06 26.4 3.5 0.11 11.4 0.3 4.1 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal Arm PF00514.21 001204674.1_03226001_1 - 1.9e-05 24.4 3.8 0.015 15.2 0.0 4.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat IFRD PF05004.11 001204674.1_03226001_1 - 0.0024 16.9 9.0 1.1 8.2 0.3 4.9 5 1 1 6 6 6 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.6 001204674.1_03226001_1 - 0.0073 15.8 7.2 0.64 9.4 0.0 5.3 4 1 1 6 6 6 1 CLASP N terminal V-ATPase_H_C PF11698.6 001204674.1_03226001_1 - 0.1 12.6 5.2 0.37 10.8 0.4 3.4 3 0 0 3 3 3 0 V-ATPase subunit H DUF655 PF04919.10 001204674.1_03226001_1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF655) HEAT_PBS PF03130.14 001204674.1_03226001_1 - 0.22 12.2 2.1 18 6.2 0.0 4.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat 7tm_1 PF00001.19 001204677.1_03223001_1 - 4.5e-69 232.5 9.1 5.6e-69 232.2 9.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001204677.1_03223001_1 - 2.1e-13 50.1 9.8 2.7e-13 49.8 9.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srt PF10321.7 001204677.1_03223001_1 - 5.3e-05 22.2 9.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.7 001204677.1_03223001_1 - 5.8e-05 22.4 13.2 5.8e-05 22.4 13.2 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001204677.1_03223001_1 - 0.12 11.9 9.4 1.8 8.1 7.7 2.6 2 1 0 2 2 2 0 Olfactory receptor DUF2873 PF11395.6 001204677.1_03223001_1 - 1.5 8.6 4.5 5.6 6.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) Innexin PF00876.16 001204665.1_03223001_1 - 1.8e-95 320.1 14.6 2e-95 319.9 14.6 1.0 1 0 0 1 1 1 1 Innexin Carn_acyltransf PF00755.18 001204619.1_03225001_2 - 7.2e-175 582.8 0.0 8.6e-175 582.5 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Trypsin PF00089.24 001311243.1_49323001_2 - 1.8e-49 168.4 5.9 2.1e-49 168.2 5.9 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001311243.1_49323001_2 - 0.0042 17.8 1.5 0.0072 17.1 1.5 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001311243.1_49323001_2 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) GST_N_3 PF13417.4 001311232.1_49322001_2 - 5.4e-18 65.0 0.0 9.9e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001311232.1_49322001_2 - 2.7e-13 49.9 0.0 4.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001311232.1_49322001_2 - 1.5e-10 41.2 0.0 2.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001311232.1_49322001_2 - 1.6e-08 34.5 0.0 4.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001311232.1_49322001_2 - 2.8e-06 27.3 0.0 4.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001311232.1_49322001_2 - 0.00035 20.3 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 001311232.1_49322001_2 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Pkinase_Tyr PF07714.15 001304470.1_25129001_1 - 1.9e-79 266.5 0.0 3e-79 265.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.26 001304470.1_25129001_1 - 7.5e-46 156.7 1.9 1.4e-45 155.9 1.9 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.23 001304470.1_25129001_1 - 4e-38 131.1 0.0 6.6e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Peripla_BP_6 PF13458.4 001304470.1_25129001_1 - 6e-16 58.9 0.0 3.5e-15 56.4 0.0 2.0 1 1 0 1 1 1 1 Periplasmic binding protein DUF4083 PF13314.4 001304470.1_25129001_1 - 0.31 10.9 1.7 0.7 9.7 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Ank_2 PF12796.5 001311269.1_05723001_3 - 1.1e-47 160.3 8.7 1.3e-13 51.2 0.0 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001311269.1_05723001_3 - 1.4e-28 98.7 4.1 2.2e-11 43.9 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.4 001311269.1_05723001_3 - 1.8e-26 91.6 2.4 6e-07 29.5 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.28 001311269.1_05723001_3 - 4.1e-25 87.0 7.5 1e-05 25.6 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.4 001311269.1_05723001_3 - 1e-23 80.7 3.9 4.8e-05 23.3 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Tropomyosin_1 PF12718.5 001311269.1_05723001_3 - 0.056 13.4 2.1 0.082 12.9 1.5 1.5 1 1 0 1 1 1 0 Tropomyosin like HSP70 PF00012.18 001311286.1_05725001_2 - 4.2e-257 854.0 6.7 4.9e-257 853.8 6.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001311286.1_05725001_2 - 1.1e-14 53.9 0.1 3.2e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.14 001311286.1_05725001_2 - 0.00036 20.2 0.0 0.0021 17.7 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.4 001311286.1_05725001_2 - 0.0031 17.8 1.1 5.3 7.4 0.0 3.5 3 1 0 3 3 3 1 Cell division protein FtsA Cnd1_N PF12922.5 001311286.1_05725001_2 - 0.13 11.9 2.5 0.23 11.1 2.5 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Hydantoinase_A PF01968.16 001311286.1_05725001_2 - 0.14 11.3 1.6 0.31 10.1 0.2 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase LBP_BPI_CETP_C PF02886.15 001311300.1_05724001_1 - 1e-24 87.2 0.2 1.7e-24 86.5 0.2 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.23 001311300.1_05724001_1 - 9.9e-11 41.4 0.1 7.2e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.9 001311300.1_05724001_1 - 0.00014 20.9 0.1 0.00026 20.1 0.1 1.5 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) Trigger_N PF05697.11 001311300.1_05724001_1 - 0.26 11.5 3.7 5.4 7.2 0.7 3.3 3 0 0 3 3 3 0 Bacterial trigger factor protein (TF) VWA PF00092.26 001311276.1_05723001_3 - 9.1e-40 136.6 2.1 2.3e-33 115.8 0.5 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.4 001311276.1_05723001_3 - 4.8e-14 52.8 0.0 1.4e-13 51.3 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.4 001311276.1_05723001_3 - 8.4e-05 22.4 0.0 0.0003 20.6 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Cas_Csa4 PF09703.8 001311276.1_05723001_3 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) Cadherin_C_2 PF16492.3 001311270.1_05722001_1 - 0.032 14.9 0.6 0.064 13.9 0.6 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF4577 PF15145.4 001311270.1_05722001_1 - 0.074 13.0 0.3 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) ATP-synt_8 PF00895.18 001311270.1_05722001_1 - 4.5 7.7 7.6 1.2 9.6 1.9 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 Hormone_3 PF00159.16 001311270.1_05722001_2 - 4.5e-14 52.1 0.8 7.6e-14 51.4 0.8 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide ETRAMP PF09716.8 001311270.1_05722001_2 - 0.011 15.6 3.0 0.034 14.1 3.0 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) zf-Paramyx-P PF13008.5 001311270.1_05722001_2 - 0.022 14.1 0.3 0.038 13.4 0.3 1.3 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein Pkinase PF00069.23 001311288.1_05723001_1 - 1.1e-66 224.8 0.1 1.3e-66 224.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001311288.1_05723001_1 - 1.5e-30 106.2 0.0 2.1e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001311288.1_05723001_1 - 1.2e-06 27.9 0.1 2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001311288.1_05723001_1 - 0.0014 18.5 0.1 0.0064 16.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.4 001311288.1_05723001_1 - 0.0086 15.3 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like OSCP PF00213.16 001311271.1_05722001_1 - 4e-44 150.6 4.5 4.6e-44 150.4 4.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit HOOK PF05622.10 001311271.1_05722001_1 - 0.15 10.0 7.3 0.15 10.0 6.6 1.2 1 1 0 1 1 1 0 HOOK protein M PF02370.14 001311271.1_05722001_1 - 2.8 8.7 8.6 7.9 7.3 2.4 3.1 2 1 0 2 2 2 0 M protein repeat DNA_methylase PF00145.15 001311308.1_05723001_1 - 4.6e-43 147.7 0.3 5.3e-43 147.5 0.3 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase MTS PF05175.12 001311308.1_05723001_1 - 0.00017 21.0 0.0 0.0069 15.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain RHD_DNA_bind PF00554.20 001311262.1_05725001_2 - 2.6e-66 222.6 0.7 4.3e-66 221.9 0.7 1.4 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 001311262.1_05725001_2 - 7.4e-41 138.2 0.0 1.4e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain TFIIA PF03153.11 001311262.1_05725001_2 - 4.8 6.9 9.3 7.3 6.3 9.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Integrin_beta PF00362.16 001311284.1_05725001_1 - 4.3e-109 363.8 0.1 6.1e-109 363.3 0.1 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.9 001311284.1_05725001_1 - 2.2e-24 84.7 1.0 4.5e-24 83.7 1.0 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.10 001311284.1_05725001_1 - 3.5e-16 59.3 5.1 3.5e-16 59.3 5.1 5.4 4 1 3 7 7 7 1 Integrin beta tail domain EGF_2 PF07974.11 001311284.1_05725001_1 - 3.5e-10 39.9 91.5 5.5e-05 23.3 17.5 6.2 3 2 1 5 5 5 4 EGF-like domain DUF815 PF05673.11 001311284.1_05725001_1 - 0.058 12.4 0.1 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RHD_DNA_bind PF00554.20 001311291.1_05728001_1 - 1.1e-56 191.3 0.2 2.1e-56 190.4 0.2 1.5 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 001311291.1_05728001_1 - 7.6e-39 131.8 0.1 1.5e-38 130.9 0.1 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.5 001311291.1_05728001_1 - 3.5e-25 88.3 2.7 1.5e-07 31.7 0.4 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001311291.1_05728001_1 - 2.8e-23 81.9 4.9 2.5e-06 27.8 0.1 4.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.28 001311291.1_05728001_1 - 2e-19 69.0 9.8 0.0048 17.2 0.1 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.4 001311291.1_05728001_1 - 8.7e-18 62.5 3.1 0.061 13.8 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.4 001311291.1_05728001_1 - 4.8e-13 48.9 11.1 2.7e-05 24.3 0.4 6.2 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Death PF00531.20 001311291.1_05728001_1 - 1.4e-05 25.0 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Death domain Sod_Fe_C PF02777.16 001311263.1_05722001_1 - 4.6e-33 113.3 0.3 1.4e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.20 001311263.1_05722001_1 - 2.5e-31 107.8 1.8 4.3e-31 107.1 1.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3227 PF11537.6 001311263.1_05722001_1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Cytochrome_P460 PF16694.3 001311263.1_05722001_1 - 0.14 12.4 0.1 0.28 11.4 0.0 1.5 2 0 0 2 2 2 0 Cytochrome P460 Sod_Cu PF00080.18 001311287.1_05722001_1 - 1.1e-48 164.8 5.0 1.4e-48 164.5 5.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.10 001311287.1_05722001_1 - 0.038 14.9 0.1 0.052 14.4 0.1 1.3 1 0 0 1 1 1 0 CHRD domain Ribosomal_60s PF00428.17 001311261.1_05722001_1 - 4.8e-27 94.2 8.0 8.4e-27 93.4 8.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.9 001311261.1_05722001_1 - 0.054 11.8 2.1 0.074 11.4 2.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF4349 PF14257.4 001311261.1_05722001_1 - 0.63 9.4 3.4 0.83 9.0 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HMG_box_2 PF09011.8 001311264.1_05724001_1 - 1.1e-30 105.9 17.3 3.4e-18 65.8 6.2 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.17 001311264.1_05724001_1 - 2.1e-29 101.6 17.8 2.4e-15 56.6 4.3 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box DUF1074 PF06382.9 001311264.1_05724001_1 - 0.018 15.1 3.1 0.018 15.1 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1074) YABBY PF04690.11 001311264.1_05724001_1 - 0.021 15.2 3.2 0.055 13.9 2.5 1.9 1 1 1 2 2 2 0 YABBY protein RXT2_N PF08595.9 001311264.1_05724001_1 - 0.027 14.3 3.2 0.047 13.6 3.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.8 001311264.1_05724001_1 - 0.036 14.3 9.9 0.069 13.4 9.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HMG_box_5 PF14887.4 001311264.1_05724001_1 - 0.28 11.0 13.8 0.05 13.4 2.3 2.3 1 1 1 2 2 2 0 HMG (high mobility group) box 5 NOA36 PF06524.10 001311264.1_05724001_1 - 1.1 8.4 9.9 1.8 7.7 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein Glycos_transf_2 PF00535.24 001311281.1_05724001_1 - 4.8e-30 104.5 0.1 8e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.20 001311281.1_05724001_1 - 1.2e-22 80.4 0.8 2.8e-22 79.2 0.8 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.4 001311281.1_05724001_1 - 4e-07 30.0 0.0 5.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.7 001311281.1_05724001_1 - 0.00011 21.7 0.0 0.00028 20.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.12 001311281.1_05724001_1 - 0.00018 20.9 0.0 0.00042 19.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Phage_FRD3 PF05798.9 001311281.1_05724001_1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage FRD3 protein Cellulase PF00150.16 001311304.1_05723001_3 - 4e-07 29.6 6.9 8.2e-07 28.6 6.9 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) bZIP_1 PF00170.19 001311289.1_05724001_1 - 2.2e-09 37.1 10.3 3.9e-09 36.3 10.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001311289.1_05724001_1 - 1.2e-07 31.5 9.5 2e-07 30.9 9.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Macoilin PF09726.7 001311289.1_05724001_1 - 0.0074 14.8 6.3 0.0096 14.4 6.3 1.1 1 0 0 1 1 1 1 Transmembrane protein bZIP_Maf PF03131.15 001311289.1_05724001_1 - 0.21 12.0 2.6 0.39 11.1 2.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4164 PF13747.4 001311289.1_05724001_1 - 0.5 10.6 3.1 0.99 9.6 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Cnn_1N PF07989.9 001311289.1_05724001_1 - 0.94 9.5 9.0 1.8 8.6 9.0 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 KLRAQ PF10205.7 001311289.1_05724001_1 - 4.8 7.4 10.3 0.56 10.3 5.7 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Glyco_hydro_16 PF00722.19 001311272.1_05724001_1 - 2e-17 63.1 0.3 3.9e-17 62.2 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PUA PF01472.18 001311272.1_05724001_1 - 0.04 13.8 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 PUA domain Chordopox_A33R PF05966.10 001311272.1_05724001_1 - 1.3 8.1 4.5 0.46 9.6 0.2 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein EF1_GNE PF00736.17 001297684.1_16822001_1 - 4.1e-36 122.9 1.1 8.2e-36 121.9 1.1 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.7 001297684.1_16822001_1 - 3.1e-12 46.5 7.0 3.1e-12 46.5 7.0 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region DUF211 PF02680.12 001297684.1_16822001_1 - 0.03 14.4 0.5 0.074 13.1 0.6 1.7 2 1 0 2 2 2 0 Uncharacterized ArCR, COG1888 MRP-S26 PF14943.4 001297684.1_16822001_1 - 0.041 13.7 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 NOP5NT PF08156.11 001297684.1_16822001_1 - 0.089 13.0 0.0 0.28 11.4 0.0 2.0 1 1 0 1 1 1 0 NOP5NT (NUC127) domain Ribosomal_L7Ae PF01248.24 001297683.1_16821001_1 - 7.3e-31 105.6 1.7 9.3e-31 105.3 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RLAN PF14401.4 001297683.1_16821001_1 - 0.0018 17.8 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain Alpha_E3_glycop PF01563.14 001297683.1_16821001_1 - 0.04 13.8 0.2 0.099 12.6 0.1 1.7 2 0 0 2 2 2 0 Alphavirus E3 glycoprotein PELOTA_1 PF15608.4 001297683.1_16821001_1 - 0.076 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain X8 PF07983.11 001297683.1_16821001_1 - 0.087 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 X8 domain ubiquitin PF00240.21 001311309.1_05721001_1 - 9.3e-35 118.1 0.3 1.2e-34 117.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.15 001311309.1_05721001_1 - 1.4e-30 104.7 9.7 2.2e-30 104.1 9.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.6 001311309.1_05721001_1 - 7.6e-17 60.8 0.4 1e-16 60.4 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001311309.1_05721001_1 - 4.6e-06 26.9 0.1 1.6e-05 25.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.4 001311309.1_05721001_1 - 0.0072 16.3 0.0 0.017 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001311309.1_05721001_1 - 0.068 13.6 0.1 0.078 13.4 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TGF_beta PF00019.18 001308541.1_04226001_2 - 9.3e-33 113.1 0.2 1.7e-32 112.3 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 001308541.1_04226001_2 - 1.1e-29 103.8 0.0 1.6e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide CENP-T_C PF15511.4 001311305.1_05721001_2 - 3e-08 33.6 0.0 4.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.15 001311305.1_05721001_2 - 4.7e-05 23.3 0.2 6.8e-05 22.8 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.4 001311305.1_05721001_2 - 8.3e-05 22.8 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.21 001311305.1_05721001_2 - 0.00041 20.4 0.1 0.00085 19.4 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001311305.1_05721001_2 - 0.00046 20.4 0.3 0.00046 20.4 0.3 1.7 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.13 001311305.1_05721001_2 - 0.0094 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.11 001311305.1_05721001_2 - 0.042 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated HMG_CoA_synt_C PF08540.8 001308307.1_06125001_3 - 4.3e-102 341.4 5.4 5.9e-102 340.9 5.4 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.15 001308307.1_06125001_3 - 1.7e-94 314.5 0.0 2.4e-94 314.0 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.8 001308307.1_06125001_3 - 0.14 11.9 0.3 0.28 10.9 0.3 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SH3_9 PF14604.4 001305987.1_04324001_1 - 4.1e-09 36.0 0.0 8.3e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 001305987.1_04324001_1 - 1.9e-05 24.1 0.0 4.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain O-FucT PF10250.7 001305987.1_04324001_1 - 2.6e-05 23.9 0.0 0.00012 21.8 0.0 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SH3_1 PF00018.26 001305987.1_04324001_1 - 8.9e-05 21.9 0.2 0.00025 20.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain NodZ PF05830.9 001305987.1_04324001_1 - 0.0038 16.0 0.2 0.013 14.2 0.1 1.8 2 0 0 2 2 2 1 Nodulation protein Z (NodZ) DUF4446 PF14584.4 001305987.1_04324001_1 - 0.79 9.6 3.6 11 5.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Ribosomal_L6 PF00347.21 001297678.1_16822001_1 - 8.3e-31 106.4 2.3 3.9e-15 56.1 0.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 DUF3858 PF12970.5 001297678.1_16822001_1 - 0.0024 17.8 0.5 2.1 8.3 0.0 2.2 2 0 0 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3858) Beta_helix PF13229.4 001297678.1_16822001_1 - 0.076 12.7 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Right handed beta helix region HSP70 PF00012.18 001305515.1_42625001_3 - 7.8e-264 876.3 9.2 8.8e-264 876.1 9.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001305515.1_42625001_3 - 6.1e-17 61.3 0.1 2.1e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.14 001305515.1_42625001_3 - 0.002 17.7 0.0 0.0059 16.2 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.18 001305515.1_42625001_3 - 0.0053 16.2 0.2 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.4 001305515.1_42625001_3 - 0.012 15.9 1.8 4 7.8 0.0 3.1 3 1 0 3 3 3 0 Cell division protein FtsA DUF1464 PF07318.10 001305515.1_42625001_3 - 0.032 13.2 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Hydantoinase_A PF01968.16 001305515.1_42625001_3 - 0.076 12.1 0.7 0.31 10.1 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF3813 PF12758.5 001305515.1_42625001_3 - 0.098 12.9 1.7 0.59 10.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) SHS2_FTSA PF02491.18 001305515.1_42625001_3 - 0.32 11.3 1.3 1.2 9.4 1.3 2.0 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA Filament PF00038.19 001311302.1_05725001_1 - 3.4e-40 138.4 40.6 8.4e-37 127.3 40.6 2.2 1 1 0 1 1 1 1 Intermediate filament protein TMF_TATA_bd PF12325.6 001311302.1_05725001_1 - 2.7e-05 24.2 29.3 0.083 13.0 6.8 4.5 2 2 2 4 4 4 3 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.10 001311302.1_05725001_1 - 0.00027 20.9 34.8 0.03 14.2 12.1 4.0 2 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.9 001311302.1_05725001_1 - 0.00072 18.4 34.9 0.0025 16.6 9.3 3.4 2 1 1 3 3 3 2 Spc7 kinetochore protein HAP1_N PF04849.11 001311302.1_05725001_1 - 0.00073 18.7 13.6 0.00073 18.7 13.6 2.8 2 2 0 2 2 2 1 HAP1 N-terminal conserved region Baculo_PEP_C PF04513.10 001311302.1_05725001_1 - 0.0009 19.2 12.1 0.065 13.1 2.2 3.5 2 2 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus ERM PF00769.17 001311302.1_05725001_1 - 0.0016 18.2 30.3 0.007 16.1 5.9 3.2 2 1 1 3 3 3 3 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.3 001311302.1_05725001_1 - 0.0017 18.8 3.7 0.0017 18.8 3.7 5.2 3 2 2 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 LTD PF00932.17 001311302.1_05725001_1 - 0.0026 18.0 0.3 0.0051 17.0 0.3 1.4 1 0 0 1 1 1 1 Lamin Tail Domain FPP PF05911.9 001311302.1_05725001_1 - 0.004 15.3 30.4 0.04 12.1 11.8 2.6 1 1 0 2 2 2 2 Filament-like plant protein, long coiled-coil ATG16 PF08614.9 001311302.1_05725001_1 - 0.0043 17.1 38.7 0.31 11.1 14.8 3.3 2 2 0 2 2 2 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.10 001311302.1_05725001_1 - 0.008 15.5 7.8 1 8.6 1.4 3.3 1 1 2 3 3 3 2 Reovirus sigma C capsid protein DUF972 PF06156.11 001311302.1_05725001_1 - 0.013 16.0 26.9 0.13 12.8 1.6 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.18 001311302.1_05725001_1 - 0.018 14.9 2.4 0.018 14.9 2.4 6.3 3 2 3 6 6 5 0 Prefoldin subunit APG6 PF04111.10 001311302.1_05725001_1 - 0.025 13.9 38.6 0.028 13.7 12.4 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 FlaC_arch PF05377.9 001311302.1_05725001_1 - 0.027 14.7 16.3 0.071 13.4 0.3 5.8 6 1 0 6 6 4 0 Flagella accessory protein C (FlaC) ADIP PF11559.6 001311302.1_05725001_1 - 0.031 14.2 31.0 0.31 11.0 0.8 3.7 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Spidroin_N PF16763.3 001311302.1_05725001_1 - 0.042 13.7 0.5 0.48 10.3 0.0 2.7 2 1 1 3 3 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF3450 PF11932.6 001311302.1_05725001_1 - 0.083 12.0 30.0 0.18 10.9 10.1 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) GAS PF13851.4 001311302.1_05725001_1 - 0.11 11.7 39.6 0.75 9.0 7.6 4.1 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.9 001311302.1_05725001_1 - 0.12 12.1 30.8 0.014 15.0 3.1 4.3 3 2 1 4 4 3 0 Phage minor structural protein GP20 IncA PF04156.12 001311302.1_05725001_1 - 0.13 11.9 45.3 8.4 6.0 16.3 4.0 2 2 0 2 2 2 0 IncA protein Fez1 PF06818.13 001311302.1_05725001_1 - 0.13 12.6 33.1 0.24 11.7 2.9 3.4 1 1 1 3 3 3 0 Fez1 HAUS-augmin3 PF14932.4 001311302.1_05725001_1 - 0.16 11.4 34.0 0.22 10.9 11.0 3.3 1 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Ax_dynein_light PF10211.7 001311302.1_05725001_1 - 0.27 11.0 23.6 1 9.2 2.0 3.9 3 1 0 3 3 3 0 Axonemal dynein light chain DUF4201 PF13870.4 001311302.1_05725001_1 - 0.35 10.4 33.6 0.16 11.5 2.9 4.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4201) BLOC1_2 PF10046.7 001311302.1_05725001_1 - 0.39 10.9 21.2 0.48 10.6 0.3 4.9 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBPIP PF07106.11 001311302.1_05725001_1 - 0.42 10.2 30.7 3 7.5 8.3 4.2 2 2 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.19 001311302.1_05725001_1 - 0.47 10.5 27.4 0.36 10.8 1.9 5.7 3 3 2 5 5 4 0 bZIP transcription factor TMF_DNA_bd PF12329.6 001311302.1_05725001_1 - 0.55 10.1 31.2 0.14 12.0 7.2 4.9 2 1 3 5 5 5 0 TATA element modulatory factor 1 DNA binding LemA PF04011.10 001311302.1_05725001_1 - 0.56 9.5 11.4 0.013 14.9 3.2 2.3 2 1 1 3 3 3 0 LemA family DUF1465 PF07323.10 001311302.1_05725001_1 - 0.57 9.9 15.7 1.1 9.0 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) Tropomyosin PF00261.18 001311302.1_05725001_1 - 0.64 9.2 34.7 0.43 9.8 18.0 3.2 2 2 1 3 3 3 0 Tropomyosin EzrA PF06160.10 001311302.1_05725001_1 - 0.72 7.8 27.0 0.7 7.9 7.3 3.1 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Lectin_N PF03954.12 001311302.1_05725001_1 - 0.96 9.1 15.1 13 5.5 0.3 4.1 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF4407 PF14362.4 001311302.1_05725001_1 - 1.1 8.5 28.6 2.9 7.0 10.0 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2203 PF09969.7 001311302.1_05725001_1 - 1.1 9.9 19.8 4.6 7.8 3.4 4.3 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) FUSC PF04632.10 001311302.1_05725001_1 - 1.1 7.6 16.6 0.31 9.4 3.6 2.4 2 1 0 2 2 2 0 Fusaric acid resistance protein family Rootletin PF15035.4 001311302.1_05725001_1 - 1.1 9.2 28.6 0.59 10.0 12.6 3.2 3 1 0 3 3 2 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.10 001311302.1_05725001_1 - 1.1 9.6 41.4 8.5 6.8 10.4 5.5 2 2 3 5 5 5 0 Cell division protein ZapB Spc29 PF17082.3 001311302.1_05725001_1 - 1.4 8.5 14.2 0.37 10.5 2.4 3.7 2 2 0 3 3 3 0 Spindle Pole Component 29 KASH_CCD PF14662.4 001311302.1_05725001_1 - 1.5 8.5 37.3 2 8.1 3.7 3.7 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH NPV_P10 PF05531.10 001311302.1_05725001_1 - 1.5 9.2 9.2 30 5.0 0.1 4.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.7 001311302.1_05725001_1 - 1.8 8.5 37.7 0.16 11.8 3.4 4.0 2 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mnd1 PF03962.13 001311302.1_05725001_1 - 2 8.1 35.4 1 9.1 4.7 3.8 1 1 2 3 3 3 0 Mnd1 family APH PF01636.21 001311302.1_05725001_1 - 2 8.1 7.0 0.16 11.8 1.4 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Golgin_A5 PF09787.7 001311302.1_05725001_1 - 2.5 7.4 35.1 0.21 10.9 11.0 3.2 2 1 1 3 3 3 0 Golgin subfamily A member 5 Atg14 PF10186.7 001311302.1_05725001_1 - 2.8 6.8 27.7 0.48 9.3 8.4 3.2 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.20 001311302.1_05725001_1 - 2.9 8.0 28.2 1.3 9.1 7.0 4.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.9 001311302.1_05725001_1 - 3.3 7.9 5.4 30 4.8 0.0 3.8 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.6 001311302.1_05725001_1 - 3.6 4.9 35.5 1.5 6.1 23.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.9 001311302.1_05725001_1 - 3.8 7.1 12.8 2 8.0 0.8 3.6 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.10 001311302.1_05725001_1 - 3.8 7.4 17.1 3.4 7.6 1.1 4.3 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.3 001311302.1_05725001_1 - 6 7.7 35.3 2 9.3 8.5 4.9 3 1 2 5 5 4 0 cGMP-dependent protein kinase interacting domain bZIP_2 PF07716.13 001311302.1_05725001_1 - 6.2 6.9 28.0 0.37 10.8 4.0 5.3 3 2 2 5 5 4 0 Basic region leucine zipper Lebercilin PF15619.4 001311302.1_05725001_1 - 6.5 6.2 34.5 0.19 11.2 10.1 3.9 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.13 001311302.1_05725001_1 - 6.7 6.4 29.7 5.2 6.8 1.7 5.6 2 2 2 5 5 5 0 Septum formation initiator CC2-LZ PF16516.3 001311302.1_05725001_1 - 6.8 6.9 26.8 2.5 8.3 2.1 4.1 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF724 PF05266.12 001311302.1_05725001_1 - 9.3 5.9 23.2 4.5 6.9 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Ribosomal_L27e PF01777.16 001297682.1_16821001_1 - 1.1e-29 102.5 13.5 1.5e-29 102.1 13.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.27 001297682.1_16821001_1 - 1.2e-06 28.1 0.1 2.5e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 KOW motif Pox_D5 PF03288.14 001297682.1_16821001_1 - 0.023 15.1 3.1 0.023 15.1 3.1 1.8 1 1 1 2 2 2 0 Poxvirus D5 protein-like Actin PF00022.17 001309101.1_42623001_1 - 5.3e-150 499.4 0.0 1.7e-149 497.7 0.0 1.6 1 1 0 1 1 1 1 Actin 7tm_1 PF00001.19 001314139.1_28523001_1 - 2.3e-44 151.5 20.8 2.8e-44 151.2 20.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001314139.1_28523001_1 - 0.00018 20.8 18.1 0.00025 20.4 18.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001314139.1_28523001_1 - 0.00083 18.6 23.7 0.002 17.4 23.7 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001314139.1_28523001_1 - 0.66 9.5 10.5 3.2 7.3 10.5 2.1 1 1 0 1 1 1 0 Olfactory receptor 7tm_1 PF00001.19 001314170.1_28523001_1 - 8e-48 162.9 12.7 1e-47 162.5 12.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001314170.1_28523001_1 - 2.4e-09 36.8 8.6 3.7e-09 36.2 8.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001314170.1_28523001_1 - 2.6e-06 27.3 9.4 0.00021 21.0 2.9 3.0 1 1 1 3 3 3 2 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001314170.1_28523001_1 - 2.7e-05 23.5 10.2 2.7e-05 23.5 10.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CBM_6 PF03422.13 001314167.1_28525001_1 - 1.8e-65 218.7 14.1 2.3e-33 115.0 1.7 3.2 3 0 0 3 3 3 2 Carbohydrate binding module (family 6) RicinB_lectin_2 PF14200.4 001314167.1_28525001_1 - 2.4e-30 105.0 18.4 6.9e-22 77.9 0.5 4.7 5 2 0 5 5 5 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_16 PF00722.19 001314167.1_28525001_1 - 4.4e-26 91.3 5.3 9e-26 90.3 5.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.13 001314167.1_28525001_1 - 3.9e-18 65.0 8.1 2.1e-10 39.4 0.8 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Ricin_B_lectin PF00652.20 001314167.1_28525001_1 - 3.7e-11 43.2 0.1 1.3e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain CopC PF04234.10 001314167.1_28525001_1 - 0.036 15.0 0.3 14 6.7 0.0 3.0 3 0 0 3 3 3 0 CopC domain DUF5011 PF16403.3 001314167.1_28525001_1 - 0.27 11.2 3.1 17 5.5 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5011) Cyt-b5 PF00173.26 001305298.1_14022001_2 - 7.3e-23 80.4 0.0 1.1e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4596 PF15363.4 001305298.1_14022001_2 - 0.064 13.4 0.4 0.11 12.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Ribosomal_S13 PF00416.20 001305367.1_14022001_2 - 6.4e-57 191.3 4.6 7.5e-57 191.1 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.9 001305367.1_14022001_2 - 0.0056 15.4 0.0 0.0065 15.1 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) FliG_C PF01706.14 001305367.1_14022001_2 - 0.1 12.7 0.4 0.73 9.9 0.1 2.1 1 1 0 2 2 2 0 FliG C-terminal domain Sdh5 PF03937.14 001305367.1_14022001_2 - 0.12 12.2 0.3 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase Peptidase_M2 PF01401.16 001305354.1_14025001_1 - 3e-204 679.7 3.7 3.6e-204 679.5 3.7 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Anthrax-tox_M PF09156.8 001305354.1_14025001_1 - 0.036 13.3 0.1 0.061 12.5 0.1 1.3 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain Cofilin_ADF PF00241.18 001308861.1_14022001_3 - 1.2e-34 119.0 0.1 1.6e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein polyprenyl_synt PF00348.15 001280918.1_06124001_2 - 2.2e-63 213.6 0.0 2.7e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase NB-ARC PF00931.20 001280918.1_06124001_2 - 0.074 11.9 0.1 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain GHMP_kinases_N PF00288.24 001280936.1_06123001_1 - 9.4e-08 32.0 2.5 1.8e-07 31.1 2.5 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1819 PF08849.9 001280936.1_06123001_1 - 0.038 13.7 0.2 0.071 12.8 0.2 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) FA_desaturase PF00487.22 001285398.1_06123001_1 - 4.3e-14 52.8 19.6 4.3e-14 52.8 19.6 2.1 2 1 1 3 3 3 2 Fatty acid desaturase polyprenyl_synt PF00348.15 001280906.1_06124001_3 - 2e-86 289.1 0.1 2.6e-86 288.7 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase BolA PF01722.16 001280930.1_06124001_2 - 1.7e-15 56.9 0.3 2.6e-15 56.3 0.3 1.3 1 0 0 1 1 1 1 BolA-like protein GHMP_kinases_N PF00288.24 001280930.1_06124001_3 - 1.8e-15 56.8 0.4 3.3e-15 55.9 0.1 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.11 001280930.1_06124001_3 - 8.1e-07 29.2 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.7 001280930.1_06124001_3 - 0.026 13.9 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature FA_desaturase PF00487.22 001286444.1_06122001_1 - 3e-06 27.2 9.5 3e-06 27.2 9.5 2.3 1 1 1 2 2 2 2 Fatty acid desaturase HMG-CoA_red PF00368.16 001308306.1_06128001_3 - 5.5e-143 476.3 0.1 7.2e-143 475.9 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.6 001308306.1_06128001_3 - 7.1e-17 61.5 9.6 3.4e-16 59.3 5.0 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.16 001308306.1_06128001_3 - 1.4e-05 23.3 3.0 2.2e-05 22.6 3.0 1.2 1 0 0 1 1 1 1 Patched family Lipase PF00151.17 001287565.1_06123001_3 - 6.1e-41 140.7 0.1 1.4e-40 139.5 0.1 1.3 1 1 0 1 1 1 1 Lipase DUF900 PF05990.10 001287565.1_06123001_3 - 0.00015 21.2 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.18 001287565.1_06123001_3 - 0.00051 19.6 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001287565.1_06123001_3 - 0.0026 18.3 0.1 0.0034 17.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.23 001287565.1_06123001_3 - 0.096 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) zf-H2C2_2 PF13465.4 001280921.1_06123001_1 - 1.3e-51 170.7 61.0 2.7e-09 36.9 2.7 8.8 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.24 001280921.1_06123001_1 - 6.8e-37 123.8 66.2 8.5e-06 25.8 1.2 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280921.1_06123001_1 - 3.5e-29 98.8 61.1 0.0011 19.5 1.2 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001280921.1_06123001_1 - 9e-15 54.4 36.5 0.025 14.7 1.2 8.3 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001280921.1_06123001_1 - 2.5e-08 33.5 57.8 0.065 13.1 1.6 9.3 9 1 0 9 9 9 6 C2H2-type zinc finger zf-met PF12874.5 001280921.1_06123001_1 - 1.5e-06 28.2 55.1 0.075 13.3 2.1 8.4 8 0 0 8 8 8 6 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.8 001280921.1_06123001_1 - 0.00029 20.7 31.9 0.22 11.5 1.3 6.2 4 1 2 6 6 6 3 Zinc ribbon domain C1_1 PF00130.20 001280921.1_06123001_1 - 0.00056 19.6 28.2 0.11 12.3 0.6 6.2 1 1 4 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) BolA PF01722.16 001280921.1_06123001_1 - 0.0028 17.8 6.4 4.9 7.4 1.0 5.2 2 2 1 3 3 3 1 BolA-like protein zf-Di19 PF05605.10 001280921.1_06123001_1 - 0.0044 17.2 36.0 0.081 13.1 0.6 5.0 2 1 4 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.4 001280921.1_06123001_1 - 0.0044 16.8 32.2 0.18 11.6 0.1 7.4 8 0 0 8 8 8 3 zinc-finger of a C2HC-type DUF3268 PF11672.6 001280921.1_06123001_1 - 0.0098 16.1 24.5 0.46 10.7 1.2 4.1 3 1 0 4 4 4 3 zinc-finger-containing domain Zf_RING PF16744.3 001280921.1_06123001_1 - 0.15 12.1 31.6 2.9 7.9 0.2 7.6 2 2 6 8 8 8 0 KIAA1045 RING finger zf-C2H2_2 PF12756.5 001280921.1_06123001_1 - 0.2 11.9 39.1 0.19 11.9 0.4 6.4 1 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.3 001280921.1_06123001_1 - 0.38 11.4 28.4 2.3 8.9 1.2 5.1 1 1 5 6 6 6 0 zinc-ribbon family zf-C2H2_11 PF16622.3 001280921.1_06123001_1 - 0.43 10.3 36.5 0.78 9.4 0.5 7.1 8 0 0 8 8 8 0 zinc-finger C2H2-type PHF5 PF03660.12 001280921.1_06123001_1 - 3.8 7.6 19.5 21 5.2 1.8 3.7 1 1 1 3 3 3 0 PHF5-like protein GAGA PF09237.9 001280921.1_06123001_1 - 5.4 6.8 13.8 18 5.1 0.1 5.0 2 1 2 5 5 5 0 GAGA factor Defensin_2 PF01097.16 001280909.1_06121001_1 - 8.5e-10 38.3 6.8 1.2e-09 37.8 6.8 1.2 1 0 0 1 1 1 1 Arthropod defensin Gamma-thionin PF00304.18 001280909.1_06121001_1 - 0.0077 16.3 5.3 0.012 15.7 5.3 1.3 1 0 0 1 1 1 1 Gamma-thionin family Toxin_2 PF00451.17 001280909.1_06121001_1 - 0.065 13.4 5.2 0.09 13.0 5.2 1.2 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 LON_substr_bdg PF02190.14 001280909.1_06121001_1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Toxin_6 PF05453.10 001280909.1_06121001_1 - 2.9 8.3 6.6 8.7 6.7 5.2 2.0 2 0 0 2 2 2 0 BmTXKS1/BmP02 toxin family SDP_N PF12278.6 001280924.1_06123001_1 - 3.9e-45 153.3 9.6 3.9e-45 153.3 9.6 3.0 2 1 0 2 2 2 1 Sex determination protein N terminal Apis_Csd PF11671.6 001280924.1_06123001_1 - 5.1e-27 94.5 47.1 7e-25 87.6 16.7 5.3 4 2 2 6 6 6 2 Complementary sex determiner protein Trypsin PF00089.24 001280894.1_06123001_2 - 4.1e-58 196.7 0.0 5.4e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin CLIP PF12032.6 001280894.1_06123001_2 - 1.7e-12 47.3 3.3 4.4e-12 46.0 3.3 1.8 1 0 0 1 1 1 1 Regulatory CLIP domain of proteinases Trypsin_2 PF13365.4 001280894.1_06123001_2 - 0.0059 17.4 0.7 0.025 15.3 0.7 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001280894.1_06123001_2 - 0.0092 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) 7tm_1 PF00001.19 001304440.1_06129001_1 - 5.9e-55 186.3 17.4 5.9e-55 186.3 17.4 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) UXS1_N PF11803.6 001311252.1_49322001_3 - 0.0092 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucuronate decarboxylase N-terminal Attacin_C PF03769.13 001311241.1_49321001_3 - 3.6e-09 36.7 0.1 4.7e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 Attacin, C-terminal region Trypsin PF00089.24 001311238.1_49322001_3 - 9e-51 172.6 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001311238.1_49322001_3 - 2.9e-08 34.6 0.1 4.2e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001311238.1_49322001_3 - 0.021 15.0 0.0 0.059 13.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) MBF2 PF15868.3 001311240.1_49322001_1 - 5.8e-14 52.3 0.0 7.5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Transcription activator MBF2 p450 PF00067.20 001311225.1_49324001_3 - 4.6e-83 279.4 0.2 5.9e-83 279.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 JHBP PF06585.9 001311246.1_49322001_3 - 5.8e-54 182.7 0.6 6.7e-54 182.5 0.6 1.0 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) UPAR_LY6 PF00021.19 001311251.1_49322001_3 - 0.029 14.9 0.5 0.05 14.2 0.5 1.3 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Cytomega_US3 PF05963.9 001311251.1_49322001_3 - 0.13 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus US3 protein 7tm_1 PF00001.19 001308538.1_04224001_3 - 9.5e-54 182.3 15.9 1.2e-53 181.9 15.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001308538.1_04224001_3 - 1.7e-06 27.5 12.3 3e-06 26.7 12.3 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.11 001308538.1_04224001_3 - 0.0064 15.5 10.4 0.052 12.5 0.4 2.2 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) 7TM_GPCR_Srx PF10328.7 001308538.1_04224001_3 - 0.15 11.2 15.8 0.25 10.5 15.1 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001308538.1_04224001_3 - 0.81 9.2 7.6 0.99 8.9 4.3 2.5 2 1 0 2 2 2 0 Olfactory receptor 7tm_1 PF00001.19 001305481.1_42623001_1 - 1.7e-40 138.8 9.7 2.2e-40 138.5 9.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001305481.1_42623001_1 - 4.2e-06 26.2 7.0 7.7e-06 25.3 7.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001305481.1_42623001_1 - 0.047 13.3 3.0 0.057 13.0 1.5 1.8 2 0 0 2 2 2 0 Olfactory receptor Ribosomal_S24e PF01282.17 001309110.1_42621001_2 - 1e-42 143.8 0.1 1.6e-42 143.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S26e PF01283.17 001309128.1_42621001_2 - 1.4e-52 176.5 9.6 1.4e-52 176.5 9.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S26e Ribosomal_L7Ae PF01248.24 001305530.1_42621001_3 - 1e-29 102.0 3.8 1.2e-29 101.7 3.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RLAN PF14401.4 001305530.1_42621001_3 - 0.065 12.7 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain FleQ PF06490.9 001305530.1_42621001_3 - 0.071 13.3 0.2 0.34 11.2 0.1 1.9 1 1 1 2 2 2 0 Flagellar regulatory protein FleQ 14-3-3 PF00244.18 001309090.1_42622001_1 - 6.6e-106 352.6 4.2 7.9e-106 352.4 4.2 1.1 1 0 0 1 1 1 1 14-3-3 protein Amidase_2 PF01510.23 001305536.1_42622001_1 - 1.4e-11 44.8 0.0 2.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase HRG PF16954.3 001305536.1_42622001_1 - 0.032 14.5 0.2 0.058 13.7 0.2 1.5 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene VirB8 PF04335.11 001305536.1_42622001_1 - 0.091 12.5 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 VirB8 protein Ribosomal_L32e PF01655.16 001309136.1_42622001_3 - 4.7e-56 187.7 3.6 6e-56 187.3 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 p450 PF00067.20 001309086.1_42624001_1 - 4.3e-74 249.8 0.0 5.1e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L44 PF00935.17 001309095.1_42621001_1 - 1.9e-32 111.5 13.1 1.9e-32 111.5 13.1 2.3 2 1 1 3 3 3 1 Ribosomal protein L44 zf-C2HCIx2C PF10782.7 001309095.1_42621001_1 - 0.069 12.9 1.5 0.069 12.9 1.5 2.6 2 0 0 2 2 2 0 Zinc-finger DUF2769 PF10967.6 001309095.1_42621001_1 - 0.26 11.8 6.5 1.9 9.1 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) Ribosomal_S19 PF00203.19 001305539.1_42622001_2 - 8.5e-36 121.6 0.7 1.2e-35 121.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DUF4700 PF15771.3 001309060.1_42623001_3 - 1.1 7.7 5.7 1.5 7.3 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4700) Glyco_transf_7N PF13733.4 001309109.1_42623001_1 - 3.4e-49 165.8 0.0 5.7e-49 165.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.12 001309109.1_42623001_1 - 3.4e-30 103.4 2.9 4.1e-29 99.9 1.3 2.3 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase DUF4046 PF13255.4 001309109.1_42623001_1 - 0.018 15.5 0.2 2.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4046) TMEM191C PF15194.4 001309109.1_42623001_1 - 0.1 12.6 1.8 0.18 11.7 1.8 1.4 1 0 0 1 1 1 0 TMEM191C family COesterase PF00135.26 001305528.1_42624001_2 - 9.3e-133 443.7 0.0 1.1e-132 443.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001305528.1_42624001_2 - 1.4e-10 41.2 0.0 4.9e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001305528.1_42624001_2 - 3e-05 23.5 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Homeobox PF00046.27 001316670.1_42623001_2 - 3.5e-20 71.4 6.4 6.2e-20 70.6 6.4 1.4 1 0 0 1 1 1 1 Homeobox domain 7tm_6 PF02949.18 001305486.1_42623001_1 - 4.8e-20 71.7 9.7 6.9e-20 71.2 9.7 1.3 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 001305486.1_42623001_1 - 4e-05 22.9 6.2 4e-05 22.9 6.2 2.3 1 1 1 2 2 2 1 7tm Chemosensory receptor Attacin_C PF03769.13 001312009.1_40322001_1 - 1.2e-25 89.9 5.6 7.7e-24 84.0 1.4 2.4 1 1 1 2 2 2 2 Attacin, C-terminal region 7tm_1 PF00001.19 001280123.1_06023001_1 - 5.5e-45 153.6 10.9 8.1e-45 153.0 10.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001280123.1_06023001_1 - 2.1e-07 30.4 10.3 2.9e-07 30.0 10.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001280123.1_06023001_1 - 0.0025 17.5 8.2 0.012 15.3 7.5 2.1 1 1 1 2 2 2 1 Olfactory receptor YycC PF14174.4 001280123.1_06023001_1 - 0.16 11.7 0.2 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 YycC-like protein Pkinase_Tyr PF07714.15 001305622.1_43228001_1 - 6.2e-85 284.5 0.0 9.3e-85 283.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.26 001305622.1_43228001_1 - 1.3e-45 156.0 0.6 2.1e-45 155.2 0.6 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.23 001305622.1_43228001_1 - 3.8e-42 144.4 0.0 6.5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Peripla_BP_6 PF13458.4 001305622.1_43228001_1 - 1.9e-16 60.6 0.0 1.2e-15 58.0 0.0 1.9 1 1 0 1 1 1 1 Periplasmic binding protein Kinase-like PF14531.4 001305622.1_43228001_1 - 0.025 13.8 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Thy1 PF02511.13 001305622.1_43228001_1 - 0.028 14.1 0.9 0.063 13.0 0.9 1.5 1 0 0 1 1 1 0 Thymidylate synthase complementing protein 7tm_6 PF02949.18 001305466.1_10623001_1 - 1.8e-99 332.6 4.9 2.4e-99 332.2 4.9 1.1 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 001305466.1_10623001_1 - 2.9e-08 33.2 6.9 2.9e-08 33.2 6.9 3.1 2 2 1 3 3 3 1 7tm Chemosensory receptor Trehalose_recp PF06151.11 001305466.1_10623001_1 - 0.00072 18.1 4.2 0.00072 18.1 4.2 1.9 2 0 0 2 2 2 1 Trehalose receptor Ion_trans_2 PF07885.14 001308631.1_01723001_1 - 6.6e-32 109.2 24.4 1.3e-17 63.4 0.4 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.29 001308631.1_01723001_1 - 9.3e-09 34.7 9.0 0.022 13.8 9.0 2.5 1 1 0 1 1 1 1 Ion transport protein ChaB PF06150.10 001308631.1_01723001_1 - 0.074 13.5 0.2 0.14 12.7 0.2 1.5 1 0 0 1 1 1 0 ChaB DUF2189 PF09955.7 001308631.1_01723001_1 - 1.1 9.4 8.6 0.56 10.3 5.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF1218 PF06749.10 001308631.1_01723001_1 - 1.1 9.6 4.0 1.6 9.1 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1218) Homeobox PF00046.27 001279318.1_01723001_1 - 2.3e-19 68.8 8.5 4.1e-19 68.0 8.5 1.4 1 0 0 1 1 1 1 Homeobox domain SDP_N PF12278.6 001310035.1_53124001_1 - 2.1e-62 209.5 8.3 2.1e-62 209.5 8.3 4.0 2 1 2 4 4 4 1 Sex determination protein N terminal Transformer PF06495.9 001310035.1_53124001_1 - 0.0013 18.7 22.4 0.0013 18.7 22.4 3.3 2 1 1 3 3 3 1 Fruit fly transformer protein IL17 PF06083.9 001308845.1_14023001_3 - 2.9e-12 46.8 1.5 5.2e-12 45.9 1.5 1.4 1 0 0 1 1 1 1 Interleukin-17 JmjC PF02373.20 001305324.1_14029001_1 - 1e-24 87.0 0.6 8.6e-24 84.1 0.2 2.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.15 001305324.1_14029001_1 - 2.5e-15 56.0 1.9 5.4e-15 54.9 1.9 1.6 1 0 0 1 1 1 1 jmjN domain ARID PF01388.19 001305324.1_14029001_1 - 9.7e-09 35.6 0.0 2.6e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Nramp PF01566.16 001305308.1_14024001_3 - 2.3e-119 398.4 14.0 2.3e-119 398.4 14.0 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF3043 PF11241.6 001305308.1_14024001_3 - 9.3 6.1 6.5 1.2 9.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Pkinase_Tyr PF07714.15 001305359.1_14024001_1 - 1.2e-33 116.4 0.0 2e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001305359.1_14024001_1 - 4.1e-33 114.7 0.0 6.7e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.10 001305359.1_14024001_1 - 1.8e-12 46.4 0.2 3.5e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.21 001305359.1_14024001_1 - 8.3e-12 45.9 10.0 2.2e-11 44.5 10.0 1.8 1 0 0 1 1 1 1 Activin types I and II receptor domain APH PF01636.21 001305359.1_14024001_1 - 2.8e-05 24.0 0.1 4.6e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.4 001305359.1_14024001_1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DM PF00751.16 001308905.1_14024001_1 - 1.3e-22 79.3 10.6 1.3e-22 79.3 10.6 2.0 2 0 0 2 2 2 1 DM DNA binding domain DMA PF03474.12 001308905.1_14024001_1 - 2.1e-19 68.7 0.1 5.1e-19 67.4 0.1 1.7 1 0 0 1 1 1 1 DMRTA motif CUE PF02845.14 001308905.1_14024001_1 - 0.016 14.8 0.0 0.059 13.0 0.0 1.9 2 0 0 2 2 2 0 CUE domain Troponin PF00992.18 001318081.1_16822001_1 - 9.9e-35 119.6 17.6 9.9e-35 119.6 17.6 2.3 3 0 0 3 3 3 1 Troponin Spc42p PF11544.6 001318081.1_16822001_1 - 0.019 14.8 3.4 0.019 14.8 3.4 3.0 2 2 0 2 2 2 0 Spindle pole body component Spc42p DUF4883 PF16224.3 001318081.1_16822001_1 - 1.6 8.9 6.6 4 7.6 0.1 2.2 1 1 0 2 2 2 0 DOmain of unknown function (DUF4883) DUF3357 PF11837.6 001318081.1_16822001_3 - 0.26 11.6 1.3 0.42 10.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Glyco_transf_29 PF00777.16 001098453.1_49423001_1 - 2.9e-70 236.6 0.1 3.5e-70 236.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Pkinase PF00069.23 214648.1_49424001_1 - 3.3e-69 233.1 0.0 5.2e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 214648.1_49424001_1 - 3.1e-34 118.3 0.0 4.9e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 214648.1_49424001_1 - 0.0013 18.6 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.18 214648.1_49424001_1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.12 214648.1_49424001_1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0220 PF05255.9 214648.1_49424001_3 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) LSM PF01423.20 001293541.1_00722001_3 - 6.1e-17 61.0 0.3 9.6e-17 60.3 0.3 1.3 1 0 0 1 1 1 1 LSM domain SNF PF00209.16 001146194.1_49426001_2 - 3.4e-193 643.0 33.9 4.2e-193 642.7 33.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CD99L2 PF12301.6 214646.1_49422001_2 - 0.44 10.7 6.0 0.65 10.1 6.0 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Lectin_C PF00059.19 214671.1_49424001_3 - 8.9e-15 55.2 1.0 1.3e-14 54.7 0.2 1.6 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.10 214671.1_49424001_3 - 0.00058 19.4 0.8 0.001 18.6 0.8 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Cys_knot PF00007.20 001281754.1_49421001_1 - 8.2e-14 51.6 6.0 9.6e-14 51.4 6.0 1.1 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.13 001281754.1_49421001_1 - 8.4e-06 25.6 4.2 8.4e-06 25.6 4.2 1.4 2 0 0 2 2 2 1 DAN domain Holin_9 PF16936.3 001287563.1_06123001_1 - 0.11 12.5 1.1 0.2 11.7 0.3 1.8 2 0 0 2 2 2 0 Putative holin NUDIX PF00293.26 001280926.1_06124001_2 - 1.7e-19 70.0 0.0 2.5e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain P-mevalo_kinase PF04275.12 001280916.1_06123001_1 - 2.4e-47 159.4 0.4 3.7e-47 158.8 0.4 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase SH3_9 PF14604.4 001304469.1_25124001_1 - 7.9e-10 38.3 0.0 1.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain O-FucT PF10250.7 001304469.1_25124001_1 - 4.2e-07 29.8 0.0 8.7e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SH3_2 PF07653.15 001304469.1_25124001_1 - 4.4e-06 26.2 0.0 8.8e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain NodZ PF05830.9 001304469.1_25124001_1 - 5.9e-06 25.2 0.2 0.00095 17.9 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein Z (NodZ) SH3_1 PF00018.26 001304469.1_25124001_1 - 0.0003 20.2 0.3 0.00072 19.0 0.0 1.8 2 0 0 2 2 2 1 SH3 domain MRP-L47 PF06984.11 001304469.1_25124001_1 - 0.098 12.7 0.9 0.28 11.2 0.4 2.0 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) YtxH PF12732.5 001304469.1_25124001_1 - 0.92 10.0 4.8 11 6.6 0.9 2.7 2 0 0 2 2 2 0 YtxH-like protein PBAN PF05874.9 001304580.1_48722001_1 - 0.086 12.6 0.3 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Pheromone biosynthesis activating neuropeptide (PBAN) KRTDAP PF15200.4 001304580.1_48722001_2 - 0.078 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Keratinocyte differentiation-associated Costars PF14705.4 001304583.1_48722001_2 - 4.1e-27 94.0 0.0 6.1e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Costars EF-hand_1 PF00036.30 001304587.1_48722001_2 - 1.4e-24 83.6 7.8 2.2e-07 29.8 1.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001304587.1_48722001_2 - 1.5e-24 86.1 4.6 1.5e-14 54.1 1.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001304587.1_48722001_2 - 1.7e-21 75.6 8.4 2e-11 43.3 1.6 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.4 001304587.1_48722001_2 - 6e-21 72.4 6.9 6.3e-07 28.7 0.1 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001304587.1_48722001_2 - 4.1e-11 41.7 5.8 0.00025 20.3 0.9 4.9 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.4 001304587.1_48722001_2 - 1e-10 41.7 0.2 6.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001304587.1_48722001_2 - 1.7e-06 27.8 0.4 0.053 13.4 0.0 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.15 001304587.1_48722001_2 - 0.21 12.0 3.2 1.4 9.4 0.5 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain Ribosomal_S30 PF04758.12 001304590.1_48722001_2 - 4.2e-29 100.4 10.6 4.2e-29 100.4 10.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S30 ubiquitin PF00240.21 001304590.1_48722001_2 - 0.029 14.0 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family CH PF00307.29 001304599.1_48722001_2 - 2e-23 82.5 0.0 3.1e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.16 001304599.1_48722001_2 - 1.8e-09 36.9 2.5 2.8e-09 36.3 2.5 1.3 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.6 001304599.1_48722001_2 - 0.0025 17.5 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain Pkinase_Tyr PF07714.15 001304600.1_48729001_2 - 3.7e-88 295.0 0.0 6.1e-88 294.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.22 001304600.1_48729001_2 - 4.4e-51 171.6 7.4 1.2e-26 92.9 0.2 3.6 3 0 0 3 3 3 2 Receptor L domain Pkinase PF00069.23 001304600.1_48729001_2 - 2e-47 161.7 0.0 3.5e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.18 001304600.1_48729001_2 - 2.6e-20 72.7 31.5 2.6e-20 72.7 31.5 2.6 3 0 0 3 3 3 1 Furin-like cysteine rich region fn3 PF00041.19 001304600.1_48729001_2 - 5e-14 52.3 11.4 0.0014 18.8 1.0 5.0 4 0 0 4 4 4 4 Fibronectin type III domain GF_recep_IV PF14843.4 001304600.1_48729001_2 - 0.00017 21.3 20.6 0.00017 21.3 20.6 2.5 1 1 1 2 2 2 2 Growth factor receptor domain IV TMEM154 PF15102.4 001304600.1_48729001_2 - 0.0076 16.0 1.2 0.027 14.2 1.2 1.9 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.4 001304600.1_48729001_2 - 0.031 14.9 0.0 0.29 11.8 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain YajC PF02699.13 001304600.1_48729001_2 - 0.039 13.7 0.3 0.18 11.6 0.4 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit Kinase-like PF14531.4 001304600.1_48729001_2 - 0.09 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ribosomal_S7e PF01251.16 001304603.1_48722001_2 - 1.5e-84 282.2 6.6 2e-84 281.8 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e FtsQ PF03799.13 001304603.1_48722001_2 - 0.00051 20.7 0.5 0.17 12.6 0.0 2.1 1 1 1 2 2 2 2 Cell division protein FtsQ Clat_adaptor_s PF01217.18 001304608.1_48722001_3 - 2e-61 205.9 8.6 2.4e-61 205.7 8.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PAS PF00989.23 001304752.1_04728001_1 - 1e-26 93.0 0.0 2.7e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001304752.1_04728001_1 - 7.4e-19 67.8 0.0 1.3e-15 57.3 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.10 001304752.1_04728001_1 - 2e-13 50.2 0.0 3.9e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.5 001304752.1_04728001_1 - 1.2e-05 25.3 0.0 0.29 11.3 0.0 2.8 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001304752.1_04728001_1 - 0.014 15.5 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 0 PAS fold Lectin_C PF00059.19 001305118.1_33322001_1 - 1.6e-09 38.3 0.1 2.1e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 Lectin C-type domain Ribosomal_S11 PF00411.17 001311173.1_16821001_1 - 7.6e-46 154.9 1.1 9.5e-46 154.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.11 001311173.1_16821001_1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) PMP22_Claudin PF00822.18 001312658.1_26523001_3 - 2.3e-13 50.2 11.1 3.3e-13 49.7 11.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001312658.1_26523001_3 - 2.6e-06 27.2 13.3 2.2e-05 24.2 13.1 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction UPF0239 PF06783.9 001312658.1_26523001_3 - 0.086 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Ion_trans PF00520.29 001314078.1_28529001_2 - 2e-30 105.7 21.2 9.4e-30 103.5 15.8 2.2 1 1 1 2 2 2 1 Ion transport protein TRP_2 PF08344.9 001314078.1_28529001_2 - 3.2e-25 88.0 1.4 6.9e-25 86.9 1.4 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.5 001314078.1_28529001_2 - 4.5e-09 36.6 4.7 1.9e-06 28.2 0.7 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PKD_channel PF08016.10 001314078.1_28529001_2 - 6.3e-09 34.9 14.4 1e-07 30.9 1.5 2.7 3 0 0 3 3 3 2 Polycystin cation channel Ank_4 PF13637.4 001314078.1_28529001_2 - 3.4e-07 30.5 0.8 0.0028 18.0 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001314078.1_28529001_2 - 0.00014 21.8 1.7 0.081 13.4 0.1 4.0 3 1 1 4 4 4 1 Ankyrin repeat Ank PF00023.28 001314078.1_28529001_2 - 0.003 17.8 0.9 0.016 15.6 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.4 001314078.1_28529001_2 - 0.0063 16.7 0.1 0.68 10.3 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Neur_chan_LBD PF02931.21 001314105.1_28523001_1 - 2.4e-40 138.1 0.1 3.1e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain 7tm_1 PF00001.19 001314138.1_28524001_1 - 6.5e-44 150.0 10.6 8.6e-44 149.6 10.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001314138.1_28524001_1 - 1.1e-13 51.1 12.8 1.6e-13 50.5 12.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001314138.1_28524001_1 - 0.00092 18.9 4.9 0.00092 18.9 4.9 2.3 3 0 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.19 001314174.1_28523001_1 - 1.2e-55 188.5 11.4 1.5e-55 188.2 11.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001314174.1_28523001_1 - 2.5e-07 30.2 9.3 3.8e-07 29.6 9.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001314174.1_28523001_1 - 0.00016 20.9 15.6 0.00025 20.3 15.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx YrhC PF14143.4 001314174.1_28523001_1 - 0.18 11.8 1.4 0.41 10.6 0.3 2.2 2 0 0 2 2 2 0 YrhC-like protein DUF1772 PF08592.9 001314174.1_28523001_1 - 5.8 7.1 8.9 17 5.6 2.4 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) LRR_8 PF13855.4 001280803.1_26527001_3 - 9.7e-48 159.7 50.1 1.8e-12 46.7 4.6 9.3 5 2 6 11 11 11 10 Leucine rich repeat 7tm_1 PF00001.19 001280803.1_26527001_3 - 1.8e-24 86.3 26.8 3.8e-24 85.2 26.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.5 001280803.1_26527001_3 - 3.7e-21 74.7 67.3 0.00059 20.0 0.4 12.7 8 3 7 15 15 15 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001280803.1_26527001_3 - 1.5e-19 70.1 42.2 2.1e-08 34.0 11.1 5.7 1 1 5 6 6 6 6 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001280803.1_26527001_3 - 1.2e-06 28.0 22.0 0.0012 18.3 1.7 6.0 1 1 4 6 6 6 4 Leucine-rich repeat 7TM_GPCR_Srsx PF10320.7 001280803.1_26527001_3 - 0.00012 21.4 25.2 0.00024 20.4 25.2 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001280803.1_26527001_3 - 0.054 12.7 29.0 0.036 13.2 26.5 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx LRR_1 PF00560.31 001280803.1_26527001_3 - 4.2 8.1 48.2 12 6.7 0.1 13.8 14 1 0 14 14 14 0 Leucine Rich Repeat LRR_6 PF13516.4 001280803.1_26527001_3 - 7.2 6.8 38.6 0.31 11.1 0.3 10.2 12 0 0 12 12 12 0 Leucine Rich repeat DUF240 PF03086.12 001280803.1_26527001_3 - 8.3 6.2 7.8 0.95 9.3 0.1 3.0 3 0 0 3 3 3 0 MG032/MG096/MG288 family 2 DAN PF03045.13 001300998.1_26521001_1 - 8.7e-23 80.4 6.2 1.1e-22 80.1 6.2 1.2 1 0 0 1 1 1 1 DAN domain 7tm_1 PF00001.19 001304597.1_48724001_1 - 5e-50 170.1 21.4 7.8e-50 169.4 21.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001304597.1_48724001_1 - 3.1e-09 36.4 22.1 4.4e-09 36.0 22.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001304597.1_48724001_1 - 5.5e-05 22.9 22.8 0.00026 20.7 22.8 1.9 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001304597.1_48724001_1 - 0.0042 16.3 18.9 0.0042 16.3 18.9 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx OrfB_IS605 PF01385.17 001304597.1_48724001_1 - 0.093 12.9 0.3 0.18 12.0 0.3 1.4 1 0 0 1 1 1 0 Probable transposase p450 PF00067.20 001304601.1_48724001_2 - 1.5e-106 356.8 0.1 2.1e-106 356.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 U79_P34 PF03064.14 001304601.1_48724001_3 - 6.9 5.8 13.1 11 5.2 13.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ribosomal_L32e PF01655.16 001304605.1_48722001_1 - 5.5e-56 187.5 4.2 7.2e-56 187.1 4.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 p450 PF00067.20 001304602.1_48725001_1 - 4.3e-107 358.6 0.3 5.1e-107 358.4 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tim44 PF04280.13 001304985.1_04822001_1 - 0.00046 20.2 0.2 0.00074 19.5 0.2 1.3 1 0 0 1 1 1 1 Tim44-like domain Amino_oxidase PF01593.22 001305311.1_14024001_2 - 3.4e-77 260.5 0.0 4.2e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001305311.1_14024001_2 - 4e-14 52.5 0.3 9.3e-14 51.3 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.22 001305311.1_14024001_2 - 3.1e-07 29.7 0.7 8.2e-07 28.3 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.22 001305311.1_14024001_2 - 9.2e-07 28.7 0.0 1.8e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.10 001305311.1_14024001_2 - 9.9e-07 28.0 0.1 0.0027 16.7 0.2 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.15 001305311.1_14024001_2 - 3.2e-06 26.4 0.0 7.3e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.17 001305311.1_14024001_2 - 7.8e-06 25.3 1.4 1.8e-05 24.0 1.3 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.12 001305311.1_14024001_2 - 1.3e-05 23.9 0.5 0.00047 18.8 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.5 001305311.1_14024001_2 - 1.5e-05 24.5 0.9 3.1e-05 23.4 0.9 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 001305311.1_14024001_2 - 9.3e-05 21.7 0.0 0.00069 18.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001305311.1_14024001_2 - 0.0001 22.7 0.4 0.00054 20.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.4 001305311.1_14024001_2 - 0.00038 19.7 0.8 0.015 14.5 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001305311.1_14024001_2 - 0.0013 17.8 2.1 0.0078 15.2 0.1 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.4 001305311.1_14024001_2 - 0.003 17.4 0.4 2.6 7.9 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding MCRA PF06100.9 001305311.1_14024001_2 - 0.0075 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 MCRA family AlaDh_PNT_C PF01262.19 001305311.1_14024001_2 - 0.022 13.9 0.2 0.036 13.2 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.16 001305311.1_14024001_2 - 0.09 12.9 0.1 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain Pkinase PF00069.23 001314157.1_28529001_1 - 4.2e-64 216.3 0.0 6.5e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001314157.1_28529001_1 - 2.3e-34 118.7 0.0 3.6e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.20 001314157.1_28529001_1 - 9.5e-30 102.1 27.6 7.3e-17 60.9 7.3 4.0 4 0 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.28 001314157.1_28529001_1 - 7.9e-14 51.7 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.22 001314157.1_28529001_1 - 7.1e-09 36.1 0.7 1.4e-08 35.1 0.7 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.21 001314157.1_28529001_1 - 0.013 15.3 0.1 0.055 13.3 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.4 001314157.1_28529001_1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.12 001314157.1_28529001_1 - 0.028 13.7 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zf_RING PF16744.3 001314157.1_28529001_1 - 0.89 9.6 12.4 1.7 8.7 4.2 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger 7tm_1 PF00001.19 001317018.1_40123001_2 - 1.2e-52 178.7 15.8 1.5e-52 178.4 15.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001317018.1_40123001_2 - 0.0001 21.6 9.1 0.00021 20.6 9.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001317018.1_40123001_2 - 0.078 12.6 7.6 0.92 9.1 7.6 2.6 1 1 0 1 1 1 0 Olfactory receptor 7tm_1 PF00001.19 001317020.1_40124001_1 - 3.8e-52 177.0 15.9 6e-52 176.4 15.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001317020.1_40124001_1 - 5e-06 26.0 9.5 5e-06 26.0 9.5 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.19 001317021.1_40124001_2 - 3.7e-40 137.7 10.4 3.7e-40 137.7 10.4 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001317021.1_40124001_2 - 3.4e-06 26.5 8.1 7.1e-06 25.5 8.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.19 001317022.1_40123001_2 - 8.4e-41 139.8 6.0 1.2e-40 139.4 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001317022.1_40123001_2 - 2.5e-06 26.9 4.3 3.5e-06 26.5 4.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx APA3_viroporin PF11289.6 001317022.1_40123001_2 - 0.032 13.6 1.3 0.058 12.8 1.3 1.3 1 0 0 1 1 1 0 Coronavirus accessory protein 3a MIF PF01187.16 001311295.1_05722001_1 - 1.7e-17 63.6 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.19 001311295.1_05722001_1 - 0.03 14.1 0.0 0.076 12.8 0.0 1.7 2 0 0 2 2 2 0 Tautomerase enzyme Toxin_30 PF08117.9 001318953.1_28622001_1 - 0.0084 16.2 7.2 0.0084 16.2 7.2 1.6 2 0 0 2 2 2 1 Ptu family Toxin_12 PF07740.10 001318953.1_28622001_1 - 0.083 13.5 8.0 0.12 12.9 8.0 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Sod_Cu PF00080.18 001304976.1_04822001_2 - 3.4e-49 166.5 3.8 4.3e-49 166.1 3.8 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Glyco_hydro_12 PF01670.14 001319287.1_16822001_1 - 1.8e-20 73.7 2.9 7.4e-20 71.7 2.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 COX2-transmemb PF09125.8 001319287.1_16822001_1 - 0.089 12.5 1.1 0.47 10.2 0.8 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane p450 PF00067.20 001319671.1_10524001_1 - 2e-79 267.4 0.0 2.5e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Apis_Csd PF11671.6 001319863.1_03023001_1 - 3.9e-50 169.5 52.1 6.6e-35 120.1 17.3 5.3 3 3 1 4 4 4 2 Complementary sex determiner protein SDP_N PF12278.6 001319863.1_03023001_1 - 2.3e-39 134.5 16.6 2.3e-39 134.5 16.6 3.3 2 1 1 3 3 3 1 Sex determination protein N terminal Ribosomal_S5 PF00333.18 001320030.1_16822001_1 - 2.1e-31 107.5 0.5 4.6e-31 106.5 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.13 001320030.1_16822001_1 - 7.5e-26 89.3 0.1 1.2e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain ATP_synth_reg PF14960.4 001320030.1_16822001_1 - 0.082 12.3 0.6 0.17 11.3 0.6 1.4 1 0 0 1 1 1 0 ATP synthase regulation FoP_duplication PF13865.4 001320030.1_16822001_1 - 0.68 10.4 16.9 1.5 9.3 16.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Cpn60_TCP1 PF00118.22 001320024.1_42625001_3 - 9.6e-87 291.5 15.0 2.4e-86 290.2 15.0 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Arm PF00514.21 001032371.2_49428001_1 - 5e-37 124.7 26.3 8.3e-07 28.7 0.2 11.3 12 0 0 12 12 12 7 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.18 001032371.2_49428001_1 - 2.4e-08 32.9 2.3 0.00017 20.1 1.5 3.2 3 0 0 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.5 001032371.2_49428001_1 - 3.3e-08 33.6 3.7 0.014 15.2 0.2 3.8 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.4 001032371.2_49428001_1 - 1.7e-06 28.2 10.4 0.2 12.1 0.1 5.5 5 1 1 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.4 001032371.2_49428001_1 - 2.1e-06 27.9 6.0 0.0026 18.0 1.0 4.4 3 1 1 4 4 4 2 HEAT repeats DUF3361 PF11841.6 001032371.2_49428001_1 - 0.00024 21.0 1.6 1.9 8.3 0.1 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3361) Pes-10 PF07149.9 001032371.2_49428001_1 - 0.00061 18.8 0.2 1 8.2 0.0 2.5 2 1 0 2 2 2 2 Pes-10 V-ATPase_H_C PF11698.6 001032371.2_49428001_1 - 0.0028 17.6 2.1 1.6 8.7 0.1 4.1 3 1 4 7 7 7 1 V-ATPase subunit H HEAT PF02985.20 001032371.2_49428001_1 - 0.0037 17.2 4.6 7.9 6.9 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Atx10homo_assoc PF09759.7 001032371.2_49428001_1 - 0.014 15.4 2.0 0.44 10.5 0.1 3.6 2 1 2 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Queuosine_synth PF02547.13 001032371.2_49428001_1 - 0.078 11.9 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein RasGEF_N_2 PF14663.4 001032371.2_49428001_1 - 0.2 11.9 7.9 71 3.7 0.3 5.1 3 3 2 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PALP PF00291.23 001242684.1_49423001_3 - 1.1e-65 221.8 0.2 1.3e-65 221.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ras PF00071.20 001242679.1_49422001_1 - 6.4e-58 194.8 0.0 7.5e-58 194.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001242679.1_49422001_1 - 1.1e-23 83.6 0.0 1.9e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001242679.1_49422001_1 - 3.6e-10 39.4 0.0 5.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001242679.1_49422001_1 - 3.2e-05 23.4 0.1 5.9e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.10 001242679.1_49422001_1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001242679.1_49422001_1 - 0.031 13.6 0.0 0.082 12.2 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ribosomal_S11 PF00411.17 001242651.1_49421001_1 - 6e-47 158.5 1.1 7.5e-47 158.2 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.11 001242651.1_49421001_1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) COesterase PF00135.26 001320389.1_10526001_1 - 1.1e-115 387.4 0.0 1.4e-115 387.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001320389.1_10526001_1 - 0.0017 18.1 0.0 0.0036 17.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold p25-alpha PF05517.10 001320389.1_10526001_1 - 0.089 12.8 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 p25-alpha AhpC-TSA PF00578.19 001204579.1_03222001_2 - 2.2e-25 88.8 0.0 3.1e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001204579.1_03222001_2 - 1.3e-11 44.3 0.0 1.7e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 001204579.1_03222001_2 - 1.2e-09 37.7 0.1 1.2e-09 37.7 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.4 001204579.1_03222001_2 - 0.028 14.5 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme WD40 PF00400.30 001170732.1_51225001_2 - 4.5e-50 166.4 15.7 2.1e-09 37.7 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.13 001170732.1_51225001_2 - 8.2e-45 152.2 0.8 1.4e-44 151.4 0.8 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.5 001170732.1_51225001_2 - 1.5e-09 37.8 0.0 0.026 14.7 0.0 5.3 2 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.3 001170732.1_51225001_2 - 0.039 12.4 0.0 1 7.7 0.0 2.5 3 0 0 3 3 3 0 beta-propeller of ELYS nucleoporin Ge1_WD40 PF16529.3 001170732.1_51225001_2 - 0.11 11.3 1.7 3.6 6.3 0.5 3.0 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.6 001170732.1_51225001_2 - 0.31 9.5 3.8 3.2 6.1 0.1 3.4 3 1 0 4 4 4 0 Nucleoporin Nup120/160 Frizzled PF01534.15 001170776.1_51225001_1 - 2e-137 457.5 23.6 4.2e-137 456.4 23.6 1.6 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.20 001170776.1_51225001_1 - 1.5e-31 109.2 2.1 1.5e-31 109.2 2.1 1.9 2 0 0 2 2 2 1 Fz domain CoA_binding_3 PF13727.4 001170776.1_51225001_1 - 0.013 15.4 0.1 0.013 15.4 0.1 2.9 3 0 0 3 3 3 0 CoA-binding domain Sterol-sensing PF12349.6 001134377.1_51228001_1 - 6.2e-20 71.4 3.5 6.2e-20 71.4 3.5 3.3 3 1 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.16 001134377.1_51228001_1 - 2.3e-18 65.6 16.3 4.1e-16 58.1 0.5 3.0 2 2 0 2 2 2 2 Patched family YfkB PF08756.8 001134377.1_51228001_1 - 0.056 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 YfkB-like domain HLH PF00010.24 001323181.1_00622001_1 - 3e-12 46.2 0.1 3e-12 46.2 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Myf5 PF12232.6 001323181.1_00622001_1 - 0.047 14.3 5.5 0.08 13.6 5.5 1.4 1 0 0 1 1 1 0 Myogenic determination factor 5 CCDC106 PF15794.3 001323181.1_00622001_1 - 0.61 9.6 5.8 0.83 9.2 5.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 UDPGT PF00201.16 001323141.1_50423001_1 - 1.3e-23 83.4 0.0 2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323141.1_50423001_1 - 3.8e-12 46.4 0.0 6.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain TadZ_N PF16968.3 001323141.1_50423001_1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal PWWP PF00855.15 001323143.1_50427001_2 - 1.1e-08 35.2 0.0 4.5e-08 33.3 0.0 2.1 1 0 0 1 1 1 1 PWWP domain DNA_methylase PF00145.15 001323143.1_50427001_2 - 1.1e-06 28.1 0.0 1.1e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase GST_N_3 PF13417.4 001323092.1_50422001_1 - 8e-17 61.3 0.0 1.2e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001323092.1_50422001_1 - 5.1e-15 55.4 0.0 9.2e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001323092.1_50422001_1 - 1.2e-09 38.2 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001323092.1_50422001_1 - 1.5e-08 34.6 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001323092.1_50422001_1 - 2.3e-08 33.7 0.0 3.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001323092.1_50422001_1 - 1.8e-05 24.7 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_tran_28_C PF04101.14 001323103.1_50423001_1 - 4.4e-15 55.9 0.0 7.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.16 001323103.1_50423001_1 - 4.3e-14 52.1 0.0 3.1e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.4 001323103.1_50423001_1 - 0.0087 15.2 0.0 0.021 14.0 0.0 1.6 1 1 1 2 2 2 1 Glycosyl transferase family 1 p450 PF00067.20 001323179.1_50424001_1 - 2.6e-106 356.0 0.8 3.1e-106 355.7 0.8 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_I_TF PF04090.10 001323179.1_50424001_1 - 0.037 13.4 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor CSG2 PF16965.3 001323179.1_50424001_1 - 0.12 11.2 0.2 0.22 10.3 0.2 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator UDPGT PF00201.16 001323153.1_50423001_1 - 5.4e-23 81.4 0.0 7.8e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323153.1_50423001_1 - 2.3e-13 50.3 0.0 3.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.18 001323153.1_50423001_1 - 0.092 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.16 001323160.1_50423001_1 - 5.8e-24 84.6 0.0 8.2e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323160.1_50423001_1 - 5.8e-13 49.0 0.0 9.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.18 001323160.1_50423001_1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.16 001323123.1_50423001_1 - 3.2e-15 55.8 0.0 4.8e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323123.1_50423001_1 - 2.8e-12 46.8 0.0 4.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.18 001323123.1_50423001_1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.16 001323176.1_50423001_1 - 1.4e-10 40.4 0.0 2.9e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323176.1_50423001_1 - 2.6e-09 37.1 0.0 4.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.4 001323176.1_50423001_1 - 0.00078 18.7 0.0 0.0024 17.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 1 Glyco_transf_28 PF03033.18 001323176.1_50423001_1 - 0.11 12.5 0.0 0.36 10.7 0.0 2.0 3 0 0 3 3 3 0 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.16 001323104.1_50423001_1 - 2.2e-15 56.3 0.0 5e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323104.1_50423001_1 - 4.1e-15 56.0 0.0 6.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.18 001323104.1_50423001_1 - 0.0033 17.3 0.1 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.4 001323104.1_50423001_1 - 0.013 14.6 1.2 0.02 14.0 0.0 1.9 2 1 1 3 3 3 0 Glycosyl transferase family 1 Caskin-tail PF16632.3 001323104.1_50423001_1 - 0.16 12.3 1.4 3.6 7.9 0.1 2.8 3 0 0 3 3 3 0 C-terminal region of Caskin GST_N PF02798.18 001323120.1_50422001_1 - 5.4e-15 55.4 0.0 1.2e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001323120.1_50422001_1 - 3.6e-14 52.8 0.0 7.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001323120.1_50422001_1 - 1.2e-07 31.8 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001323120.1_50422001_1 - 1.6e-07 31.3 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001323120.1_50422001_1 - 7.8e-07 28.8 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001323120.1_50422001_1 - 5.4e-05 23.2 0.1 0.00011 22.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001323120.1_50422001_1 - 0.059 13.0 0.1 0.2 11.3 0.1 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain UDPGT PF00201.16 001323151.1_50423001_1 - 1.2e-15 57.2 0.0 1.9e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323151.1_50423001_1 - 1.5e-13 51.0 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.4 001323151.1_50423001_1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Glyco_transf_28 PF03033.18 001323151.1_50423001_1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain ProRS-C_2 PF09181.8 001323151.1_50423001_1 - 0.058 13.4 0.1 0.66 10.0 0.0 2.6 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal GFP PF01353.20 001323182.1_00622001_1 - 1.5e-53 181.4 0.2 1.7e-53 181.2 0.2 1.0 1 0 0 1 1 1 1 Green fluorescent protein UDPGT PF00201.16 001323113.1_50423001_1 - 2.4e-11 43.0 0.0 3.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323113.1_50423001_1 - 2.1e-10 40.7 0.0 3.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Epimerase_2 PF02350.17 001323113.1_50423001_1 - 0.0042 15.8 0.0 0.011 14.5 0.0 1.6 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_1_4 PF13692.4 001323113.1_50423001_1 - 0.079 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_3 PF13528.4 001323113.1_50423001_1 - 0.086 11.9 0.0 4 6.5 0.0 2.4 2 1 1 3 3 3 0 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.14 001323112.1_50423001_1 - 2.7e-10 40.4 0.0 4.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.16 001323112.1_50423001_1 - 2.8e-10 39.5 0.0 4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Chitin_synth_2 PF03142.13 001323091.1_50429001_1 - 2.1e-30 105.7 9.0 1.8e-27 96.0 1.9 2.9 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.4 001323091.1_50429001_1 - 2.2e-13 50.4 2.5 2.2e-13 50.4 2.5 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.4 001323091.1_50429001_1 - 4.8e-08 33.1 0.1 8.7e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.24 001323091.1_50429001_1 - 0.0073 16.0 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.4 001323091.1_50429001_1 - 0.011 15.1 0.1 0.075 12.4 0.1 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 21 S1FA PF04689.11 001323091.1_50429001_1 - 0.025 14.6 3.5 5.7 7.0 0.1 3.3 2 0 0 2 2 2 0 DNA binding protein S1FA DUF5134 PF17197.2 001323091.1_50429001_1 - 0.095 12.5 1.3 0.24 11.2 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) UDPGT PF00201.16 001323159.1_50423001_1 - 1.6e-25 89.8 0.0 2.6e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323159.1_50423001_1 - 9.3e-13 48.4 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.18 001323159.1_50423001_1 - 0.018 15.0 0.0 0.081 12.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.16 001323115.1_50423001_1 - 3.1e-14 52.5 0.0 6.3e-14 51.5 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323115.1_50423001_1 - 2e-10 40.7 0.0 3.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.16 001323127.1_50423001_1 - 8.5e-20 70.9 0.0 1.6e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323127.1_50423001_1 - 1e-10 41.7 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_tran_28_C PF04101.14 001323121.1_50423001_1 - 3.2e-15 56.4 0.0 7.2e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.16 001323121.1_50423001_1 - 9.8e-15 54.2 0.0 5.9e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.18 001323121.1_50423001_1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.4 001323121.1_50423001_1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 1 UDPGT PF00201.16 001323172.1_50423001_1 - 1.8e-25 89.6 0.0 2.6e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323172.1_50423001_1 - 5.5e-14 52.4 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.16 001323178.1_50423001_1 - 6.9e-13 48.1 0.0 1.6e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323178.1_50423001_1 - 8.1e-10 38.8 0.0 3.7e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.18 001323178.1_50423001_1 - 0.001 18.9 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.4 001323178.1_50423001_1 - 0.018 14.2 0.1 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 1 Glyco_hydro_18 PF00704.26 001323144.1_50424001_2 - 6.9e-93 311.6 4.4 9.9e-93 311.1 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.22 001323144.1_50424001_2 - 3.2e-14 52.7 6.1 3.2e-14 52.7 6.1 1.8 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain RAP1 PF07218.9 001323144.1_50424001_2 - 8 4.5 11.0 11 4.0 11.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_tran_28_C PF04101.14 001323122.1_50423001_1 - 3.5e-16 59.5 0.0 7.4e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.16 001323122.1_50423001_1 - 2.7e-15 56.0 0.0 6.4e-15 54.8 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.4 001323122.1_50423001_1 - 0.0082 15.3 0.0 0.022 13.9 0.0 1.7 1 1 1 2 2 2 1 Glycosyl transferase family 1 Glyco_transf_28 PF03033.18 001323122.1_50423001_1 - 0.0089 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain FIVAR PF07554.11 001323122.1_50423001_1 - 0.068 13.5 0.8 0.24 11.8 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain UDPGT PF00201.16 001323158.1_50423001_1 - 5.3e-26 91.3 0.0 1.4e-25 89.9 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323158.1_50423001_1 - 3.8e-13 49.6 0.0 6.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Epimerase_2 PF02350.17 001323158.1_50423001_1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glycos_transf_1 PF00534.18 001323158.1_50423001_1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 YqhG PF11079.6 001323158.1_50423001_1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Glyco_trans_1_4 PF13692.4 001323158.1_50423001_1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 UDPGT PF00201.16 001323105.1_50423001_1 - 1.7e-18 66.6 0.0 3.7e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001323105.1_50423001_1 - 1.2e-15 57.8 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.4 001323105.1_50423001_1 - 0.03 13.4 1.4 0.039 13.1 0.0 1.9 2 1 1 3 3 3 0 Glycosyl transferase family 1 Glyco_transf_28 PF03033.18 001323105.1_50423001_1 - 0.076 12.9 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Homeobox PF00046.27 001323477.1_43824001_3 - 2.2e-19 68.9 4.3 4.2e-19 68.0 4.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001323477.1_43824001_3 - 0.013 15.2 0.9 0.03 14.1 0.9 1.6 1 0 0 1 1 1 0 Homeobox KN domain Filament PF00038.19 001323478.1_43826001_1 - 1.2e-76 258.2 63.1 1.1e-75 254.9 63.1 2.0 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.17 001323478.1_43826001_1 - 5.3e-16 58.8 0.1 1.2e-15 57.7 0.1 1.5 1 0 0 1 1 1 1 Lamin Tail Domain Reo_sigmaC PF04582.10 001323478.1_43826001_1 - 0.0027 17.0 11.2 0.11 11.7 3.4 3.0 1 1 2 3 3 3 3 Reovirus sigma C capsid protein FPP PF05911.9 001323478.1_43826001_1 - 0.0031 15.7 45.4 0.064 11.4 11.1 2.6 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil IncA PF04156.12 001323478.1_43826001_1 - 0.0094 15.6 8.9 0.0094 15.6 8.9 3.6 1 1 3 4 4 3 2 IncA protein TPR_MLP1_2 PF07926.10 001323478.1_43826001_1 - 0.04 13.9 52.6 1.8 8.5 19.9 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.16 001323478.1_43826001_1 - 0.23 11.5 16.9 0.15 12.1 0.3 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper Golgin_A5 PF09787.7 001323478.1_43826001_1 - 0.37 10.1 46.9 0.41 9.9 21.8 2.9 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF3584 PF12128.6 001323478.1_43826001_1 - 0.39 8.1 48.3 0.0021 15.6 26.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Shugoshin_N PF07558.9 001323478.1_43826001_1 - 1.7 8.5 5.7 3 7.6 0.2 3.6 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Spc7 PF08317.9 001323478.1_43826001_1 - 4.2 6.0 50.5 4.3 6.0 24.8 3.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.10 001323478.1_43826001_1 - 4.9 7.1 17.1 20 5.1 4.6 4.2 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MbeD_MobD PF04899.10 001323478.1_43826001_1 - 5.2 7.1 13.8 9 6.4 0.5 4.2 2 2 2 4 4 4 0 MbeD/MobD like GATA PF00320.25 001323475.1_43824001_1 - 1.5e-28 98.0 16.3 3.3e-14 52.1 6.9 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.10 001323475.1_43824001_1 - 4.6e-05 22.7 7.7 0.061 12.7 2.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.8 001323475.1_43824001_1 - 0.015 15.2 2.3 1.2 9.2 0.1 2.6 2 1 1 3 3 3 0 Zinc ribbon domain ArfGap PF01412.16 001323475.1_43824001_1 - 0.026 14.4 6.3 0.35 10.8 0.2 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.9 001323475.1_43824001_1 - 0.12 12.2 4.4 2.1 8.2 0.2 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RRN7 PF11781.6 001323475.1_43824001_1 - 0.19 11.3 9.3 0.79 9.3 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Elf1 PF05129.11 001323475.1_43824001_1 - 0.23 11.4 5.9 4.1 7.4 0.2 3.0 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Auto_anti-p27 PF06677.10 001323475.1_43824001_1 - 0.29 11.2 5.1 1.6 8.8 0.3 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2387 PF09526.8 001323475.1_43824001_1 - 0.31 11.1 4.3 17 5.5 0.3 3.3 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) DZR PF12773.5 001323475.1_43824001_1 - 0.76 9.7 5.8 12 5.9 0.3 2.6 1 1 1 2 2 2 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.10 001323475.1_43824001_1 - 2.1 8.6 10.5 0.75 10.1 2.1 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase eIF-5_eIF-2B PF01873.15 001323475.1_43824001_1 - 3.1 7.6 8.5 9.5 6.0 1.2 2.7 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Vps36-NZF-N PF16988.3 001323475.1_43824001_1 - 5.1 6.4 8.4 0.36 10.1 0.3 3.0 2 1 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn_Tnp_IS1595 PF12760.5 001323475.1_43824001_1 - 7 6.6 8.7 2.3 8.1 0.6 2.7 2 1 0 3 3 3 0 Transposase zinc-ribbon domain Homeobox PF00046.27 001323484.1_43822001_1 - 1e-21 76.3 4.3 1.7e-21 75.6 4.3 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001323484.1_43822001_1 - 0.027 14.2 0.1 0.1 12.4 0.1 2.1 1 0 0 1 1 1 0 Homeobox KN domain FGF PF00167.16 001323481.1_43822001_1 - 1.5e-23 83.1 0.3 2.6e-23 82.4 0.3 1.3 1 0 0 1 1 1 1 Fibroblast growth factor Hormone_recep PF00104.28 001323480.1_43824001_1 - 7.2e-41 139.9 0.2 1.2e-40 139.1 0.0 1.4 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001323480.1_43824001_1 - 3.9e-30 104.0 17.6 1e-29 102.7 17.6 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Forkhead PF00250.16 001323482.1_43823001_1 - 2.7e-32 110.8 0.3 4.8e-32 110.0 0.3 1.3 1 0 0 1 1 1 1 Forkhead domain 7tm_6 PF02949.18 001323845.1_10223001_1 - 4.9e-100 334.5 6.3 7.2e-100 333.9 6.3 1.2 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 001323845.1_10223001_1 - 4.3e-08 32.6 7.3 4.3e-08 32.6 7.3 3.4 3 1 0 3 3 3 2 7tm Chemosensory receptor Trehalose_recp PF06151.11 001323845.1_10223001_1 - 0.003 16.1 4.2 0.003 16.1 4.2 1.9 2 0 0 2 2 2 1 Trehalose receptor wnt PF00110.17 001323831.1_40723001_1 - 1.1e-84 284.4 26.5 1.4e-84 284.1 26.5 1.0 1 0 0 1 1 1 1 wnt family Baculo_Y142 PF04913.10 001323831.1_40723001_1 - 0.067 11.7 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Baculovirus Y142 protein 7tm_6 PF02949.18 001323842.1_10223001_1 - 2.5e-31 108.8 24.0 5.1e-31 107.8 24.0 1.5 1 1 0 1 1 1 1 7tm Odorant receptor 7tm_6 PF02949.18 001323847.1_10223001_1 - 2.1e-33 115.6 15.5 2.8e-33 115.2 15.5 1.2 1 0 0 1 1 1 1 7tm Odorant receptor Homeobox PF00046.27 001323819.1_40724001_2 - 1e-20 73.2 4.1 2.3e-20 72.0 4.1 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001323819.1_40724001_2 - 0.013 15.3 0.1 0.055 13.2 0.1 2.1 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.27 001323813.1_40722001_1 - 2.8e-20 71.7 8.4 5.1e-20 70.9 8.4 1.5 1 0 0 1 1 1 1 Homeobox domain Engrail_1_C_sig PF10525.7 001323813.1_40722001_1 - 1.2e-09 37.0 0.0 2.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain Homeobox_KN PF05920.9 001323813.1_40722001_1 - 0.18 11.6 1.0 0.49 10.2 1.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.27 001323804.1_40723001_1 - 9.7e-20 70.0 3.4 2.4e-19 68.7 3.4 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001323804.1_40723001_1 - 0.0055 16.5 1.1 0.013 15.2 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.24 001323803.1_40724001_3 - 3.9e-16 58.4 37.2 1.2e-05 25.3 0.2 6.7 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001323803.1_40724001_3 - 2.2e-14 53.0 40.3 1.3e-07 31.6 0.3 5.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 001323803.1_40724001_3 - 0.0014 19.1 5.6 0.013 16.1 0.2 7.2 7 0 0 7 7 7 3 C2H2-type zinc finger DUF4764 PF15961.3 001323803.1_40724001_3 - 0.3 9.6 2.0 0.44 9.0 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-C2H2_jaz PF12171.6 001323803.1_40724001_3 - 1.1 9.6 18.4 5.1 7.4 0.1 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding SIX1_SD PF16878.3 001323801.1_40723001_3 - 8.5e-47 158.1 1.0 3.6e-46 156.1 0.1 2.2 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeobox PF00046.27 001323801.1_40723001_3 - 2.2e-12 46.5 3.5 5.1e-12 45.3 1.1 2.2 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.9 001323801.1_40723001_3 - 2.5e-10 40.0 1.1 7e-10 38.5 1.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.20 001323801.1_40723001_3 - 0.05 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix 7tm_6 PF02949.18 001323848.1_10223001_1 - 4.4e-36 124.4 23.4 6e-36 124.0 23.4 1.1 1 0 0 1 1 1 1 7tm Odorant receptor ICMT PF04140.12 001323848.1_10223001_1 - 6.7 7.1 10.4 3.9 7.8 5.2 3.0 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ski_Sno PF02437.15 001323830.1_40729001_1 - 1.1e-35 121.5 0.0 2.3e-35 120.5 0.0 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family TGF_beta PF00019.18 001323812.1_40726001_3 - 4.6e-34 117.3 0.2 9.4e-34 116.3 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 001323812.1_40726001_3 - 3e-29 102.4 3.4 2.8e-28 99.2 3.4 2.0 1 1 0 1 1 1 1 TGF-beta propeptide 7tm_6 PF02949.18 001323849.1_10223001_1 - 2.5e-44 151.5 8.7 3.3e-44 151.1 8.7 1.1 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_6 PF02949.18 001323844.1_10223001_1 - 5.3e-28 97.9 9.0 5.3e-28 97.9 9.0 1.4 1 1 1 2 2 2 1 7tm Odorant receptor Frizzled PF01534.15 001323836.1_40727001_2 - 1e-67 228.4 26.0 1.5e-67 227.9 26.0 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.20 001323836.1_40727001_2 - 8e-10 39.3 1.5 8e-10 39.3 1.5 2.4 2 0 0 2 2 2 1 Fz domain 7tm_1 PF00001.19 001323836.1_40727001_2 - 1.2 8.2 19.4 1.8 7.6 18.5 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Auxin_canalis PF05703.9 001323836.1_40727001_2 - 2.8 7.7 6.2 1.3 8.8 3.0 1.8 2 0 0 2 2 2 0 Auxin canalisation 7tm_6 PF02949.18 001323841.1_10223001_1 - 1.1e-38 132.9 13.0 1.1e-38 132.9 13.0 1.3 2 0 0 2 2 2 1 7tm Odorant receptor MgtE PF01769.14 001323841.1_10223001_1 - 0.037 14.3 1.3 0.037 14.3 1.3 3.5 2 1 0 2 2 2 0 Divalent cation transporter 7tm_6 PF02949.18 001323850.1_10223001_1 - 4.7e-53 180.2 14.2 4.7e-53 180.2 14.2 2.0 2 0 0 2 2 2 1 7tm Odorant receptor Bap31 PF05529.10 001323850.1_10223001_1 - 0.82 9.1 7.2 0.049 13.1 0.8 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4149 PF13664.4 001323850.1_10223001_1 - 1.3 9.2 5.5 0.2 11.9 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) zf-C2H2 PF00096.24 001323805.1_40729001_3 - 2.8e-14 52.6 44.5 0.00064 19.9 0.4 6.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001323805.1_40729001_3 - 1.3e-08 34.7 6.7 3.8e-07 30.1 1.1 8.1 8 1 0 8 8 8 3 Zinc-finger double domain FOXP-CC PF16159.3 001323805.1_40729001_3 - 0.0026 18.2 36.0 0.02 15.4 0.6 7.4 4 1 3 7 7 7 3 FOXP coiled-coil domain zf-C2H2_4 PF13894.4 001323805.1_40729001_3 - 0.032 14.9 0.3 0.032 14.9 0.3 7.8 6 0 0 6 6 6 0 C2H2-type zinc finger wnt PF00110.17 001323810.1_40724001_1 - 4.6e-119 397.4 21.7 5.5e-119 397.1 21.7 1.1 1 0 0 1 1 1 1 wnt family 7tm_6 PF02949.18 001323846.1_10223001_1 - 1.7e-43 148.8 12.4 2.7e-43 148.1 12.4 1.3 1 0 0 1 1 1 1 7tm Odorant receptor bZIP_1 PF00170.19 001293577.1_51223001_3 - 6.9e-10 38.7 10.0 1.5e-09 37.7 10.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001293577.1_51223001_3 - 1.4e-05 24.9 10.2 2.9e-05 23.9 10.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper KLRAQ PF10205.7 001293577.1_51223001_3 - 0.013 15.6 3.4 0.027 14.6 3.4 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.15 001293577.1_51223001_3 - 0.035 14.5 5.1 0.074 13.4 5.1 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor WD40_alt PF14077.4 001293577.1_51223001_3 - 0.11 12.2 0.5 0.22 11.2 0.5 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF3450 PF11932.6 001293577.1_51223001_3 - 0.21 10.7 6.0 0.06 12.5 3.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.13 001293577.1_51223001_3 - 0.44 10.2 3.2 1.2 8.9 3.2 1.8 1 0 0 1 1 1 0 Septum formation initiator p450 PF00067.20 001039452.1_51223001_1 - 1.7e-79 267.6 2.6 6.9e-79 265.6 2.6 1.7 1 1 0 1 1 1 1 Cytochrome P450 T3SchapCesA PF11439.6 001039452.1_51223001_1 - 0.062 13.3 0.2 2.8 8.0 0.1 2.6 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA Phospholip_A2_2 PF05826.10 001145917.1_51222001_1 - 1.3e-37 127.8 4.5 1.8e-37 127.3 4.5 1.2 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.17 001145917.1_51222001_1 - 0.025 14.9 10.4 0.29 11.4 0.8 2.3 1 1 1 2 2 2 0 Phospholipase A2 Daxx PF03344.13 001145917.1_51222001_1 - 0.041 13.8 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain MNNL PF07657.11 001145917.1_51222001_1 - 0.053 13.4 3.6 0.088 12.7 3.6 1.4 1 0 0 1 1 1 0 N terminus of Notch ligand PLA2G12 PF06951.9 001145917.1_51222001_1 - 0.32 10.7 5.9 3.8 7.2 5.9 2.0 1 1 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Neur_chan_LBD PF02931.21 001160070.1_51223001_1 - 6.6e-76 254.4 0.0 8.8e-76 254.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001160070.1_51223001_1 - 2.3e-39 135.7 1.6 5.1e-31 108.4 0.1 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Tetraspannin PF00335.18 001160070.1_51223001_1 - 1.7 8.2 4.8 0.35 10.5 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family Neur_chan_LBD PF02931.21 001109780.1_51224001_1 - 5.8e-41 140.2 0.7 8.6e-41 139.6 0.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001109780.1_51224001_1 - 1.6e-26 93.7 4.3 2.2e-25 90.0 4.3 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region 7tm_6 PF02949.18 001323851.1_10223001_1 - 2.5e-42 144.9 13.2 3.4e-42 144.5 13.2 1.1 1 0 0 1 1 1 1 7tm Odorant receptor Chitin_bind_4 PF00379.21 001162705.2_00722001_2 - 3.5e-13 49.7 7.0 5.5e-13 49.1 7.0 1.3 1 0 0 1 1 1 1 Insect cuticle protein Mg_chelatase PF01078.19 001162705.2_00722001_3 - 3 7.0 6.0 2.1 7.5 0.6 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Proteasome PF00227.24 001162747.2_00723001_1 - 2.2e-30 105.4 0.0 2.7e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Thioredoxin PF00085.18 001162712.2_00723001_1 - 4.9e-16 58.4 0.0 7.2e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.4 001162712.2_00723001_1 - 0.023 15.0 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Ferritin PF00210.22 001293325.1_00723001_2 - 0.04 13.7 0.1 0.089 12.6 0.0 1.5 2 0 0 2 2 2 0 Ferritin-like domain WRW PF10206.7 001126211.2_00722001_3 - 5.5e-48 161.4 0.3 5.5e-48 161.4 0.3 1.5 2 0 0 2 2 2 1 Mitochondrial F1F0-ATP synthase, subunit f F1F0-ATPsyn_F PF10791.7 001126211.2_00722001_3 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi FA_desaturase PF00487.22 001204956.1_00724001_1 - 1.1e-14 54.8 16.4 1.1e-14 54.8 16.4 1.4 1 1 0 1 1 1 1 Fatty acid desaturase FA_desaturase PF00487.22 001204957.1_00724001_3 - 7e-15 55.4 16.3 7e-15 55.4 16.3 1.4 1 1 0 1 1 1 1 Fatty acid desaturase AGTRAP PF06396.9 001293425.1_00723001_2 - 0.00026 20.6 0.5 0.00041 20.0 0.5 1.4 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) NOA36 PF06524.10 001293439.1_00723001_1 - 6.3e-18 65.1 26.2 8.5e-18 64.6 26.2 1.1 1 0 0 1 1 1 1 NOA36 protein DNA_pol_phi PF04931.11 001293439.1_00723001_1 - 0.28 9.1 26.6 0.39 8.7 26.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.7 001293439.1_00723001_1 - 2.1 7.3 25.6 3.4 6.6 25.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.9 001293439.1_00723001_1 - 4.6 6.6 14.7 7.1 6.0 14.7 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.10 001293439.1_00723001_1 - 7.1 5.8 17.2 10 5.3 17.2 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.10 001293439.1_00723001_2 - 1.8e-118 395.4 47.4 2.3e-118 395.0 47.4 1.1 1 0 0 1 1 1 1 NOA36 protein Orai-1 PF07856.10 001205126.1_00722001_1 - 0.035 13.7 0.1 8.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Mediator of CRAC channel activity Shisa PF13908.4 001205126.1_00722001_1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator ATP_bind_3 PF01171.18 001293473.1_00723001_2 - 2.1e-17 63.4 0.0 2.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.3 001293473.1_00723001_2 - 3.8e-17 61.3 1.3 3.8e-17 61.3 1.3 2.6 3 0 0 3 3 3 1 Zinc-ribbon TF_Zn_Ribbon PF08271.10 001293473.1_00723001_2 - 1.6 8.2 12.8 0.55 9.6 0.2 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding RecR PF02132.13 001293473.1_00723001_2 - 1.8 8.1 9.0 0.092 12.2 1.7 2.5 3 0 0 3 3 3 0 RecR protein Thioredoxin PF00085.18 001246016.2_00722001_2 - 4.1e-31 106.9 0.1 6e-31 106.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.4 001246016.2_00722001_2 - 7.5e-07 29.4 0.1 6.5e-06 26.4 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.4 001246016.2_00722001_2 - 9.2e-06 25.5 0.1 1.6e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.4 001246016.2_00722001_2 - 5.4e-05 23.3 0.1 0.001 19.2 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.19 001246016.2_00722001_2 - 0.0006 19.6 0.1 0.002 17.9 0.1 1.8 1 1 1 2 2 2 1 AhpC/TSA family HyaE PF07449.9 001246016.2_00722001_2 - 0.00092 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.4 001246016.2_00722001_2 - 0.001 18.9 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.4 001246016.2_00722001_2 - 0.0015 18.1 0.1 0.0023 17.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.4 001246016.2_00722001_2 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.8 001246016.2_00722001_2 - 0.019 14.5 0.0 0.052 13.1 0.0 1.6 1 1 1 2 2 2 0 Redoxin DUF836 PF05768.12 001246016.2_00722001_2 - 0.029 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF2847 PF11009.6 001246016.2_00722001_2 - 0.055 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) TMEM70 PF06979.10 001293494.1_00722001_2 - 6.9e-46 155.8 2.9 1.1e-45 155.2 2.9 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Nodulin PF02451.13 001293494.1_00722001_2 - 0.015 14.7 0.2 0.023 14.1 0.2 1.2 1 0 0 1 1 1 0 Nodulin CAP PF00188.24 001162342.1_00722001_2 - 1.9e-23 83.6 0.8 2.3e-23 83.2 0.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Endonuclea_NS_2 PF13930.4 001162668.2_00722001_3 - 1.9e-12 47.3 0.0 2.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2617 PF10936.6 001162668.2_00722001_3 - 0.064 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2617 Endonuclease_NS PF01223.21 001162668.2_00722001_3 - 0.097 12.3 0.3 0.15 11.7 0.3 1.4 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease CN_hydrolase PF00795.20 001162107.2_00723001_2 - 6.7e-58 195.9 0.0 7.8e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_1 PF01344.23 001162107.2_00723001_2 - 0.084 12.3 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Kelch motif Epimerase PF01370.19 001162775.2_00723001_3 - 7.1e-53 179.4 0.0 9.4e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001162775.2_00723001_3 - 2.4e-15 56.6 0.4 1.8e-14 53.7 0.0 1.9 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.13 001162775.2_00723001_3 - 3.1e-06 26.4 1.6 1.7e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001162775.2_00723001_3 - 3.6e-06 26.1 0.0 4.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.17 001162775.2_00723001_3 - 0.00024 20.0 0.1 0.00075 18.4 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_M22 PF00814.23 001162118.2_00723001_3 - 1.3e-87 293.8 0.0 1.6e-87 293.5 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family UMP1 PF05348.9 001162309.2_00722001_1 - 2e-17 63.4 0.3 6.4e-17 61.7 0.2 1.8 1 1 1 2 2 2 1 Proteasome maturation factor UMP1 DcpS_C PF11969.6 001162438.1_00723001_3 - 7.3e-30 103.6 0.1 1.5e-29 102.6 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.10 001162438.1_00723001_3 - 3.9e-21 75.7 0.1 8.2e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Chitin_bind_4 PF00379.21 001161959.2_00722001_3 - 1.5e-15 57.3 0.8 2.5e-15 56.6 0.8 1.4 1 0 0 1 1 1 1 Insect cuticle protein PrgI PF12666.5 001161959.2_00722001_3 - 0.45 11.1 5.9 4.3 8.0 0.1 2.2 2 0 0 2 2 2 0 PrgI family protein PrmA PF06325.11 001162292.2_00723001_3 - 4e-13 49.3 0.3 5.7e-13 48.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.4 001162292.2_00723001_3 - 1e-11 44.7 0.1 1.8e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain SOSSC PF15925.3 001162292.2_00723001_3 - 1.3e-11 45.5 0.9 1e-09 39.5 0.1 2.4 1 1 1 2 2 2 1 SOSS complex subunit C MTS PF05175.12 001162292.2_00723001_3 - 1.6e-11 43.9 0.0 2.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.8 001162292.2_00723001_3 - 6.3e-08 32.4 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.16 001162292.2_00723001_3 - 6.6e-08 32.3 0.5 2.7e-07 30.3 0.5 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.4 001162292.2_00723001_3 - 2.5e-07 31.2 0.1 4.9e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.13 001162292.2_00723001_3 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.10 001162292.2_00723001_3 - 0.00019 21.9 0.1 0.00039 20.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001162292.2_00723001_3 - 0.00024 21.7 0.0 0.00059 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.14 001162292.2_00723001_3 - 0.00052 19.2 0.0 0.00087 18.5 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_23 PF13489.4 001162292.2_00723001_3 - 0.00099 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.14 001162292.2_00723001_3 - 0.0024 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_9 PF08003.9 001162292.2_00723001_3 - 0.0037 16.1 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Molybdopterin PF00384.20 001167975.1_34225001_3 - 2.6e-60 204.5 0.0 1e-58 199.2 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.4 001167975.1_34225001_3 - 2.1e-18 66.0 0.0 8.9e-18 64.0 0.0 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.7 001167975.1_34225001_3 - 2.8e-16 58.7 0.1 6.2e-16 57.5 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.9 001167975.1_34225001_3 - 8e-13 48.7 0.5 1.8e-12 47.6 0.5 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.25 001167975.1_34225001_3 - 2.1e-08 33.9 0.1 2.1e-08 33.9 0.1 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain EamA PF00892.18 001159899.1_34225001_3 - 1.9e-10 40.9 23.7 8.2e-06 25.9 4.0 2.9 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.13 001159899.1_34225001_3 - 2.3e-07 30.1 1.0 2.3e-07 30.1 1.0 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter CRT-like PF08627.8 001159899.1_34225001_3 - 7.6e-06 25.0 5.0 7.6e-06 25.0 5.0 2.2 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.10 001159899.1_34225001_3 - 2.8e-05 23.7 12.4 3.1e-05 23.5 3.2 2.5 2 0 0 2 2 2 2 Solute carrier family 35 TPT PF03151.14 001159899.1_34225001_3 - 0.0037 16.5 8.5 0.0092 15.2 8.5 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family MRJP PF03022.14 001161514.1_34224001_3 - 4.6e-39 134.4 0.0 6.8e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein PQQ PF01011.19 001161514.1_34224001_3 - 0.073 12.9 0.2 1.3 8.9 0.0 3.1 4 0 0 4 4 4 0 PQQ enzyme repeat 7tm_6 PF02949.18 001190550.1_34223001_1 - 9.1e-45 152.9 4.8 1.3e-44 152.5 4.8 1.2 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 001190550.1_34223001_1 - 3.4e-11 42.8 11.6 7.5e-11 41.7 11.6 1.5 1 1 0 1 1 1 1 7tm Chemosensory receptor Med5 PF08689.8 001190550.1_34223001_1 - 0.0015 16.3 0.3 0.0024 15.7 0.3 1.2 1 0 0 1 1 1 1 Mediator complex subunit Med5 Kazal_2 PF07648.13 001256032.1_03128001_3 - 3e-07 30.4 17.4 0.0029 17.6 0.2 5.4 4 1 0 4 4 4 3 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.19 001256040.1_03129001_2 - 0.0008 18.6 0.0 1.8 7.6 0.9 3.8 3 1 0 3 3 3 3 7 transmembrane receptor (rhodopsin family) FOXP-CC PF16159.3 001104949.1_03127001_1 - 4.9e-33 113.4 2.9 4.9e-33 113.4 2.9 3.6 3 1 1 4 4 4 1 FOXP coiled-coil domain Forkhead PF00250.16 001104949.1_03127001_1 - 5.8e-27 93.7 0.3 1.7e-26 92.2 0.3 1.8 1 0 0 1 1 1 1 Forkhead domain JTB PF05439.10 001206467.1_03126001_1 - 1.5e-34 118.2 5.9 1.5e-34 118.2 5.9 2.1 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) Methyltransf_32 PF13679.4 001206467.1_03126001_1 - 3e-09 36.9 8.9 3.4e-08 33.5 8.9 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001206467.1_03126001_1 - 3.8e-09 36.4 0.6 8.4e-09 35.3 0.6 1.6 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.12 001206467.1_03126001_1 - 9.2e-08 31.8 7.7 0.0063 15.9 6.4 2.8 1 1 1 2 2 2 2 Methyltransferase TRM13 Methyltransf_25 PF13649.4 001206467.1_03126001_1 - 5.6e-05 23.7 0.0 0.0002 21.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.12 001206467.1_03126001_1 - 8.9e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.13 001206467.1_03126001_1 - 0.00041 19.6 0.0 0.0008 18.6 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.15 001206467.1_03126001_1 - 0.00058 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.5 001206467.1_03126001_1 - 0.0025 17.6 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GST_C_3 PF14497.4 001206467.1_03126001_1 - 0.03 14.4 0.1 0.52 10.4 0.1 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ubie_methyltran PF01209.16 001206467.1_03126001_1 - 0.039 13.2 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.17 001206467.1_03126001_1 - 0.056 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GST_C_2 PF13410.4 001206467.1_03126001_1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_12 PF08242.10 001206467.1_03126001_1 - 0.076 13.6 0.2 0.25 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain 7tm_1 PF00001.19 001037318.2_03126001_1 - 1.7e-67 227.4 3.6 2.6e-67 226.8 3.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001037318.2_03126001_1 - 2.8e-12 46.5 0.1 9.7e-12 44.7 0.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Neur_chan_LBD PF02931.21 001143878.1_03123001_1 - 2.4e-32 112.0 0.2 3.2e-32 111.6 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001143878.1_03123001_1 - 5.3e-14 52.7 8.6 9.2e-14 51.9 0.6 2.5 3 0 0 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region GST_N_3 PF13417.4 033330.1_34223120_2 - 9.2e-15 54.7 0.0 2.3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 033330.1_34223120_2 - 4.2e-14 52.5 0.0 8.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 033330.1_34223120_2 - 4e-10 39.7 0.0 6.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 033330.1_34223120_2 - 0.00013 22.0 0.1 0.00021 21.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 033330.1_34223120_2 - 0.0038 17.3 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DM PF00751.16 024131.1_03127120_3 - 9.8e-16 57.3 15.2 9.8e-16 57.3 15.2 1.9 2 0 0 2 2 2 1 DM DNA binding domain DSX_dimer PF08828.8 024131.1_03127120_3 - 7.1e-08 31.7 0.2 1.3e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Doublesex dimerisation domain Aldo_ket_red PF00248.19 027628.1_34223120_1 - 7.7e-06 25.1 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.19 027628.1_34223120_3 - 2.6e-27 95.6 0.0 3.9e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.19 027629.1_34223120_1 - 2.1e-18 66.4 0.0 1.1e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family Aldo_ket_red PF00248.19 027629.1_34223120_3 - 3.4e-11 42.7 0.0 4.7e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.20 001327966.1_03124001_1 - 3.1e-105 352.4 0.0 3.5e-105 352.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 7tm_1 PF00001.19 001328483.1_02823001_1 - 1.8e-41 142.0 12.4 2.2e-41 141.7 12.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001328483.1_02823001_1 - 3.6e-13 49.4 12.4 5e-13 48.9 12.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001328483.1_02823001_1 - 6.1e-05 22.8 9.2 0.00023 20.9 9.2 2.0 1 1 0 1 1 1 1 Olfactory receptor Ctr PF04145.13 001328483.1_02823001_1 - 1.1 9.7 5.5 0.27 11.7 0.8 2.3 2 1 0 2 2 2 0 Ctr copper transporter family His_Phos_1 PF00300.20 001328486.1_02823001_1 - 3.9e-33 114.7 0.0 2e-27 96.0 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.20 001328488.1_02823001_3 - 7.3e-06 25.4 0.0 0.0007 18.9 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Vitellogenin_N PF01347.20 001328484.1_02829001_3 - 3.5e-194 646.6 4.8 4.5e-194 646.2 4.8 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.9 001328484.1_02829001_3 - 9.2e-23 80.8 2.3 1.8e-22 79.9 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) VWD PF00094.23 001328484.1_02829001_3 - 8.1e-17 61.8 0.1 2.6e-16 60.2 0.1 2.0 1 0 0 1 1 1 1 von Willebrand factor type D domain 7tm_6 PF02949.18 001328478.1_02824001_1 - 7.6e-37 126.9 12.1 1.2e-36 126.2 12.1 1.3 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_6 PF02949.18 001328477.1_02824001_3 - 9.2e-100 333.6 5.0 9.2e-100 333.6 5.0 1.4 2 0 0 2 2 2 1 7tm Odorant receptor 7tm_7 PF08395.10 001328477.1_02824001_3 - 3.8e-08 32.8 7.3 3.8e-08 32.8 7.3 3.1 2 2 1 3 3 3 1 7tm Chemosensory receptor Trehalose_recp PF06151.11 001328477.1_02824001_3 - 0.0012 17.3 4.6 0.0012 17.3 4.6 2.0 2 0 0 2 2 2 1 Trehalose receptor 7tm_1 PF00001.19 001328485.1_02823001_1 - 1e-52 178.9 16.1 1.3e-52 178.6 16.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.7 001328485.1_02823001_1 - 0.0001 21.6 14.7 0.00087 18.5 14.7 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.7 001328485.1_02823001_1 - 0.00046 19.5 14.4 0.0011 18.2 14.4 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001328485.1_02823001_1 - 0.019 14.6 8.4 0.12 11.9 8.4 2.3 1 1 0 1 1 1 0 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001328485.1_02823001_1 - 0.38 9.9 18.5 0.46 9.6 17.3 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Period_C PF12114.6 001328481.1_02827001_3 - 3.8e-34 117.9 1.3 3.8e-34 117.9 1.3 4.6 6 0 0 6 6 6 2 Period protein 2/3C-terminal region PAS PF00989.23 001328481.1_02827001_3 - 4.3e-19 68.5 0.0 3.3e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001328481.1_02827001_3 - 1.7e-16 60.2 0.0 1.6e-13 50.6 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.10 001328481.1_02827001_3 - 1.2e-15 57.4 0.0 1.8e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.5 001328481.1_02827001_3 - 2.1e-05 24.6 0.0 0.3 11.2 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001328481.1_02827001_3 - 0.039 14.1 0.0 15 5.8 0.0 2.5 2 0 0 2 2 2 0 PAS fold 7tm_1 PF00001.19 001328482.1_02823001_1 - 7.9e-44 149.8 12.1 9.5e-44 149.5 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001328482.1_02823001_1 - 1.8e-07 30.7 11.6 2.5e-07 30.2 11.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001328482.1_02823001_1 - 0.0024 17.5 9.2 0.0046 16.6 7.4 2.0 1 1 1 2 2 2 1 Olfactory receptor YycC PF14174.4 001328482.1_02823001_1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 YycC-like protein Apis_Csd PF11671.6 001328487.1_02823001_1 - 1.6e-69 232.4 33.3 1.6e-69 232.4 33.3 3.7 3 0 0 3 3 3 1 Complementary sex determiner protein SDP_N PF12278.6 001328487.1_02823001_1 - 2.7e-35 121.3 13.5 2.7e-35 121.3 13.5 2.6 3 0 0 3 3 3 1 Sex determination protein N terminal 7tm_6 PF02949.18 001328600.1_19623001_1 - 1.6e-78 263.8 14.0 2.3e-78 263.3 14.0 1.2 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_6 PF02949.18 001328602.1_19623001_1 - 1.8e-54 184.9 10.3 2.1e-54 184.6 10.3 1.1 1 0 0 1 1 1 1 7tm Odorant receptor DUF1335 PF07056.9 001328602.1_19623001_1 - 0.0016 18.4 0.1 0.0031 17.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1335) 7tm_6 PF02949.18 001328601.1_19623001_1 - 2.6e-137 457.0 8.3 2.6e-137 457.0 8.3 1.4 2 0 0 2 2 2 1 7tm Odorant receptor 7tm_7 PF08395.10 001328601.1_19623001_1 - 5e-06 25.8 5.6 5e-06 25.8 5.6 3.4 2 2 1 3 3 3 1 7tm Chemosensory receptor Trehalose_recp PF06151.11 001328601.1_19623001_1 - 0.00093 17.7 3.9 0.00093 17.7 3.9 2.1 2 0 0 2 2 2 1 Trehalose receptor 7tm_6 PF02949.18 001328603.1_19623001_1 - 5e-76 255.6 9.6 6e-76 255.4 9.6 1.1 1 0 0 1 1 1 1 7tm Odorant receptor His_Phos_2 PF00328.20 001328489.1_02823001_1 - 7.3e-23 81.4 0.7 1.3e-12 47.7 0.0 3.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) HEAT PF02985.20 001328624.1_17623001_1 - 0.055 13.6 0.0 0.96 9.7 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat PBP_GOBP PF01395.20 001297691.1_16821001_1 - 1.1e-14 54.4 1.6 1.3e-14 54.2 1.6 1.1 1 0 0 1 1 1 1 PBP/GOBP family CagD PF16567.3 001297691.1_16821001_1 - 0.05 13.3 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD Ribosomal_S7 PF00177.19 001297692.1_16822001_1 - 6.5e-36 123.1 1.3 8e-36 122.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S8 PF00410.17 001297693.1_16821001_1 - 1.6e-22 79.7 0.0 2.1e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Methyltransf_23 PF13489.4 001301361.1_16822001_1 - 2.6e-18 66.4 0.0 3.4e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001301361.1_16822001_1 - 3.6e-18 65.9 0.0 1.2e-17 64.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.10 001301361.1_16822001_1 - 1.9e-17 63.6 0.0 1.2e-16 61.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.4 001301361.1_16822001_1 - 1.6e-16 60.3 0.0 4.1e-16 59.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001301361.1_16822001_1 - 3.4e-16 59.6 0.1 1.1e-15 58.0 0.0 1.9 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.16 001301361.1_16822001_1 - 1.7e-10 40.5 0.0 2.1e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.12 001301361.1_16822001_1 - 5.2e-06 26.0 0.0 8.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.18 001301361.1_16822001_1 - 3.3e-05 23.2 0.0 4.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.9 001301361.1_16822001_1 - 3.5e-05 23.4 0.0 5.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.17 001301361.1_16822001_1 - 0.00021 21.3 0.0 0.00027 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.4 001301361.1_16822001_1 - 0.00046 20.1 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.14 001301361.1_16822001_1 - 0.0014 17.7 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme RrnaAD PF00398.18 001301361.1_16822001_1 - 0.0024 16.8 0.0 0.0046 15.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.17 001301361.1_16822001_1 - 0.0026 17.4 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TMEM189_B_dmain PF10520.7 001301361.1_16822001_1 - 0.0037 17.3 0.4 0.0061 16.6 0.4 1.4 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain TPMT PF05724.9 001301361.1_16822001_1 - 0.035 13.6 0.0 0.078 12.5 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DREV PF05219.10 001301361.1_16822001_1 - 0.039 12.9 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.15 001301361.1_16822001_1 - 0.05 12.9 0.0 0.13 11.6 0.0 1.8 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.5 001301361.1_16822001_1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L18A PF01775.15 001297688.1_16822001_1 - 3e-55 185.4 0.2 4.3e-55 184.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A GST_C_3 PF14497.4 001329187.1_16822001_1 - 3.4e-22 78.4 0.3 5.3e-22 77.7 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001329187.1_16822001_1 - 2.3e-11 43.8 0.0 4.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001329187.1_16822001_1 - 6e-08 32.7 0.2 1.5e-07 31.4 0.1 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001329187.1_16822001_1 - 4.6e-07 30.0 0.0 1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001329187.1_16822001_1 - 0.00024 21.2 0.0 0.00045 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.2 001329187.1_16822001_1 - 0.0007 20.2 0.0 0.002 18.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain DUF4348 PF14254.4 001329187.1_16822001_1 - 0.03 13.4 0.1 0.063 12.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4348) Tom37 PF10568.7 001329187.1_16822001_1 - 0.039 14.0 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein ABC_tran PF00005.25 001329181.1_16824001_1 - 5e-25 88.5 0.0 7.8e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.5 001329181.1_16824001_1 - 1.7e-12 47.0 12.2 2.6e-12 46.4 12.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.4 001329181.1_16824001_1 - 2.5e-09 37.2 1.9 2.1e-05 24.3 0.3 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.22 001329181.1_16824001_1 - 4.7e-07 29.3 22.1 4.7e-07 29.3 22.1 1.6 2 0 0 2 2 2 1 ABC-2 type transporter SMC_N PF02463.17 001329181.1_16824001_1 - 0.00049 19.5 0.0 0.0026 17.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.14 001329181.1_16824001_1 - 0.0078 16.0 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.4 001329181.1_16824001_1 - 0.02 14.4 0.2 0.25 10.8 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.4 001329181.1_16824001_1 - 0.036 13.7 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.4 001329181.1_16824001_1 - 0.055 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.4 001329181.1_16824001_1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.12 001329181.1_16824001_1 - 0.095 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.7 001329181.1_16824001_1 - 0.11 12.1 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.4 001329181.1_16824001_1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ferritin PF00210.22 001329183.1_16822001_1 - 1.2e-06 28.4 0.2 2.2e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF4576 PF15144.4 001329183.1_16822001_1 - 0.088 12.6 0.2 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) Ribosomal_L15e PF00827.15 001329185.1_16822001_1 - 8.6e-93 309.2 5.6 9.7e-93 309.1 5.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ion_trans PF00520.29 001329182.1_16829001_3 - 1.7e-240 793.6 93.7 9.6e-70 234.5 10.4 4.1 4 0 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.11 001329182.1_16829001_3 - 3.8e-29 102.2 0.9 3.8e-29 102.2 0.9 2.3 3 0 0 3 3 3 1 Sodium ion transport-associated Na_trans_cytopl PF11933.6 001329182.1_16829001_3 - 8e-28 97.6 16.5 8e-28 97.6 16.5 2.3 2 1 0 2 2 2 1 Cytoplasmic domain of voltage-gated Na+ ion channel PKD_channel PF08016.10 001329182.1_16829001_3 - 1.1e-13 50.5 85.4 3.3e-05 22.6 3.5 9.4 5 3 3 8 8 8 7 Polycystin cation channel GPHH PF16905.3 001329182.1_16829001_3 - 9.1e-08 31.7 0.0 2.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated UPF0239 PF06783.9 001329182.1_16829001_3 - 3.7 7.7 5.6 0.84 9.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) SieB PF14163.4 001329182.1_16829001_3 - 3.9 6.8 9.6 0.9 8.9 0.2 4.0 4 0 0 4 4 4 0 Super-infection exclusion protein B Peptidase_C1 PF00112.21 001329180.1_16823001_1 - 8.2e-53 179.6 4.8 1.2e-52 179.1 4.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.11 001329180.1_16823001_1 - 1.4e-10 40.7 0.0 6.7e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.13 001329180.1_16823001_1 - 0.045 12.4 2.1 1.4 7.4 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Mt_ATP-synt_B PF05405.12 001329184.1_16822001_1 - 3.6e-36 124.1 5.4 4.3e-36 123.9 5.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ank_2 PF12796.5 001163712.1_03123001_1 - 8.2e-29 99.9 1.7 2.1e-14 53.7 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.28 001163712.1_03123001_1 - 4.2e-28 96.4 4.3 1.2e-06 28.6 0.1 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.4 001163712.1_03123001_1 - 4.5e-26 87.9 2.2 1.9e-05 24.6 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.4 001163712.1_03123001_1 - 2.6e-25 88.3 4.2 2.7e-08 34.1 0.4 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.4 001163712.1_03123001_1 - 1.4e-24 85.6 3.0 8.1e-08 32.3 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) MRP-L28 PF09812.7 001163712.1_03123001_1 - 0.0058 16.6 0.1 0.0098 15.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF2384 PF09722.8 001163712.1_03123001_1 - 0.05 13.5 0.1 0.63 10.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) 7tm_1 PF00001.19 001330549.1_35423001_1 - 1.9e-67 227.2 15.6 2.6e-67 226.8 15.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001330549.1_35423001_1 - 1.2e-09 37.9 14.6 1.9e-09 37.1 14.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001330549.1_35423001_1 - 0.0026 17.0 12.8 0.0026 17.0 12.8 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001330549.1_35423001_1 - 0.006 16.2 9.8 0.025 14.2 7.5 2.3 2 0 0 2 2 2 1 Olfactory receptor DUF3754 PF12576.6 001330549.1_35423001_1 - 4.5 7.1 6.3 37 4.2 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) 7tm_1 PF00001.19 001330550.1_35423001_1 - 1.1e-68 231.2 11.6 1.8e-68 230.6 11.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001330550.1_35423001_1 - 3.9e-09 36.1 13.7 3.8e-06 26.3 12.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001330550.1_35423001_1 - 0.013 15.1 9.7 0.031 13.9 9.2 1.8 2 0 0 2 2 2 0 Olfactory receptor DUF4199 PF13858.4 001330550.1_35423001_1 - 0.044 14.0 9.4 0.18 12.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) NADH_B2 PF14813.4 001330550.1_35423001_1 - 0.1 12.3 0.3 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 7tm_1 PF00001.19 001330546.1_35424001_1 - 7.8e-74 248.1 6.3 2.9e-73 246.3 6.3 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001330546.1_35424001_1 - 2.8e-15 56.3 13.0 6.1e-11 42.1 5.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.7 001330546.1_35424001_1 - 2.3e-05 23.8 9.5 0.00028 20.2 1.8 2.6 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001330546.1_35424001_1 - 0.0003 20.5 6.6 0.00071 19.3 6.6 1.7 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001330546.1_35424001_1 - 0.0077 15.4 8.2 0.022 14.0 8.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1510 PF07423.9 001330546.1_35424001_1 - 0.0092 15.3 1.4 0.024 13.9 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) 7TM_GPCR_Srbc PF10316.7 001330546.1_35424001_1 - 0.11 11.9 6.0 0.018 14.5 1.6 2.0 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc FAM176 PF14851.4 001330546.1_35424001_1 - 1.3 8.5 5.8 4.1 6.9 5.8 1.8 1 1 0 1 1 1 0 FAM176 family Vitellogenin_N PF01347.20 001331111.1_06129001_1 - 4.7e-54 183.7 4.5 7.6e-54 183.0 4.5 1.4 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.9 001331111.1_06129001_1 - 2.4e-05 23.6 1.6 3.1e-05 23.3 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1943) VWD PF00094.23 001331111.1_06129001_1 - 0.053 13.6 0.1 0.053 13.6 0.1 3.5 5 0 0 5 5 5 0 von Willebrand factor type D domain Glyco_hydro_18 PF00704.26 001044626.1_51223001_3 - 6.5e-62 209.9 0.0 7.6e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Acetyltransf_1 PF00583.23 001145908.1_51223001_2 - 4.6e-05 23.5 0.0 7.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.5 001145908.1_51223001_2 - 0.00096 18.9 0.0 0.0023 17.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.4 001145908.1_51223001_2 - 0.0031 17.5 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.5 001145908.1_51223001_2 - 0.0077 16.5 0.0 0.018 15.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain 7tm_7 PF08395.10 001168453.1_51224001_1 - 1.2e-34 120.1 70.2 1.6e-20 73.5 33.9 2.8 2 1 0 2 2 2 2 7tm Chemosensory receptor BTB PF00651.29 001111264.1_51225001_1 - 2.7e-24 85.4 0.0 4.7e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.24 001111264.1_51225001_1 - 1.1e-07 31.8 8.6 0.0034 17.6 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 001111264.1_51225001_1 - 1.8e-06 27.6 7.0 0.0016 18.2 1.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.4 001111264.1_51225001_1 - 3.4e-06 27.3 8.1 0.022 15.4 1.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.10 001111264.1_51225001_1 - 0.00026 21.1 0.4 0.00073 19.6 0.4 1.8 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.5 001111264.1_51225001_1 - 0.00038 20.6 6.4 0.14 12.5 0.4 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.4 001111264.1_51225001_1 - 0.00068 19.3 3.0 0.073 12.9 0.3 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.6 001111264.1_51225001_1 - 0.0089 16.2 1.2 4.2 7.7 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.4 001111264.1_51225001_1 - 0.27 11.6 3.7 3.6 8.1 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_11 PF16622.3 001111264.1_51225001_1 - 0.7 9.6 8.8 1.3 8.7 2.6 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Metallothio_2 PF01439.16 001110435.1_51223001_3 - 0.048 14.5 3.1 0.48 11.3 2.1 2.5 2 0 0 2 2 2 0 Metallothionein Phospholip_A2_2 PF05826.10 001145989.1_51222001_1 - 1.8e-38 130.5 2.6 1.8e-38 130.5 2.6 1.5 2 0 0 2 2 2 1 Phospholipase A2 Topoisom_I PF01028.18 001145989.1_51222001_1 - 0.038 13.1 0.3 0.051 12.7 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core Phospholip_A2_1 PF00068.17 001145989.1_51222001_1 - 0.44 10.8 13.9 51 4.2 12.5 2.7 1 1 0 1 1 1 0 Phospholipase A2 7tm_1 PF00001.19 001145478.1_51223001_2 - 1.5e-40 139.0 17.9 2.3e-40 138.4 17.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.7 001145478.1_51223001_2 - 3.1e-06 26.6 14.8 3.1e-06 26.6 14.8 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Chitin_bind_4 PF00379.21 001167848.1_51223001_1 - 4.4e-12 46.2 4.9 7.9e-12 45.4 4.9 1.4 1 0 0 1 1 1 1 Insect cuticle protein DUF4794 PF16042.3 001167848.1_51223001_1 - 0.027 15.3 10.8 0.11 13.3 10.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4794) ADH_zinc_N PF00107.24 001160238.1_51223001_2 - 2.8e-23 82.1 0.2 5e-23 81.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001160238.1_51223001_2 - 4e-23 81.2 2.7 4e-23 81.2 2.7 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain UDPG_MGDP_dh_N PF03721.12 001160238.1_51223001_2 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.17 001160238.1_51223001_2 - 0.029 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CBM_14 PF01607.22 001168433.1_51223001_1 - 3.1e-10 39.9 4.3 4.8e-10 39.3 4.3 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain bZIP_Maf PF03131.15 001170823.1_51224001_3 - 1.4e-06 28.6 9.8 2.5e-06 27.8 9.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.19 001170823.1_51224001_3 - 7.3e-06 25.9 14.2 7.3e-06 25.9 14.2 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001170823.1_51224001_3 - 0.00084 19.2 16.6 0.0015 18.4 16.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF4200 PF13863.4 001170823.1_51224001_3 - 0.13 12.6 9.3 0.18 12.0 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) JIP_LZII PF16471.3 001170823.1_51224001_3 - 0.15 12.1 2.1 0.31 11.1 2.1 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II ASD2 PF08687.9 001170823.1_51224001_3 - 0.18 11.3 5.9 0.25 10.8 5.9 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Mnd1 PF03962.13 001170823.1_51224001_3 - 0.46 10.2 5.1 0.73 9.5 5.1 1.2 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.12 001170823.1_51224001_3 - 1.5 8.4 5.2 2.4 7.8 5.2 1.3 1 0 0 1 1 1 0 IncA protein OS-D PF03392.11 001309441.1_28621001_1 - 4.8e-29 100.2 1.7 5.6e-29 100.0 1.7 1.1 1 0 0 1 1 1 1 Insect pheromone-binding family, A10/OS-D zf-trcl PF13451.4 001309441.1_28621001_1 - 0.0042 16.8 0.3 0.0076 16.0 0.3 1.4 1 0 0 1 1 1 1 Probable zinc-ribbon domain PBP_GOBP PF01395.20 001309441.1_28621001_1 - 0.0057 16.7 0.4 0.0084 16.1 0.4 1.2 1 0 0 1 1 1 1 PBP/GOBP family PAE PF03283.11 001309441.1_28621001_1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase SinI PF08671.8 001309441.1_28621001_1 - 1.5 8.5 3.5 0.99 9.1 0.2 2.3 2 1 0 2 2 2 0 Anti-repressor SinI p450 PF00067.20 001319647.1_48724001_2 - 8.8e-105 351.0 1.2 1.1e-104 350.7 1.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 7tm_2 PF00002.22 001305350.1_14024001_1 - 6.4e-48 163.0 9.4 9.3e-48 162.5 9.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.20 001305350.1_14024001_1 - 2.5e-12 46.8 5.9 6.3e-12 45.5 5.9 1.7 1 0 0 1 1 1 1 Hormone receptor domain Git3 PF11710.6 001305350.1_14024001_1 - 0.42 10.2 5.4 0.073 12.7 0.8 1.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Homeobox PF00046.27 001323788.1_36422001_1 - 3.9e-21 74.5 2.6 6.2e-21 73.9 2.6 1.3 1 0 0 1 1 1 1 Homeobox domain SatD PF16264.3 001323788.1_36422001_1 - 0.028 13.9 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 SatD family (SatD) DUF447 PF04289.10 001323788.1_36422001_1 - 0.07 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) CPSF73-100_C PF11718.6 001323788.1_36422001_1 - 0.18 11.3 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term KAR9 PF08580.8 001323788.1_36422001_1 - 0.54 8.6 5.9 0.55 8.6 5.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ribosomal_S17e PF00833.16 001304589.1_48722001_2 - 8.8e-62 206.3 1.3 1.1e-61 206.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 14-3-3 PF00244.18 001323787.1_36423001_2 - 1e-104 348.8 3.2 1.2e-104 348.5 3.2 1.1 1 0 0 1 1 1 1 14-3-3 protein COX2_TM PF02790.13 001162520.1_51223001_3 - 2.1 8.4 11.3 0.61 10.1 2.0 3.1 2 1 1 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain 7tm_1 PF00001.19 001162520.1_51223001_3 - 2.8 6.9 33.9 4.4e+02 -0.2 33.9 3.0 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.4 001308899.1_14025001_3 - 5.6e-26 89.9 47.4 2.4e-08 33.5 1.1 8.1 6 3 0 6 6 6 5 Leucine rich repeat TIR PF01582.18 001308899.1_14025001_3 - 3.3e-20 72.5 0.1 5.5e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001308899.1_14025001_3 - 3.1e-11 43.1 62.1 1.5e-05 25.1 0.2 10.2 6 1 5 12 12 12 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001308899.1_14025001_3 - 2.3e-07 30.9 0.0 5.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001308899.1_14025001_3 - 0.0048 16.3 20.3 5.1 6.4 0.0 5.0 3 1 2 5 5 5 3 Leucine-rich repeat LRR_5 PF13306.4 001308899.1_14025001_3 - 0.044 13.6 12.2 0.72 9.7 0.0 4.5 2 2 1 3 3 3 0 Leucine rich repeats (6 copies) LRRNT PF01462.16 001308899.1_14025001_3 - 1.9 8.1 9.3 0.32 10.5 3.3 2.8 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.31 001308899.1_14025001_3 - 7.5 7.3 46.8 1.4 9.5 0.3 11.8 12 2 0 12 12 12 0 Leucine Rich Repeat Auts2 PF15336.4 001304592.1_48729001_1 - 0.12 12.3 4.9 0.2 11.7 4.9 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Pkinase_Tyr PF07714.15 001304592.1_48729001_3 - 2e-94 315.6 0.0 4.2e-94 314.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Recep_L_domain PF01030.22 001304592.1_48729001_3 - 5.5e-49 164.8 4.8 5.2e-25 87.6 0.3 3.3 3 0 0 3 3 3 2 Receptor L domain Pkinase PF00069.23 001304592.1_48729001_3 - 3.4e-39 134.7 0.0 6.1e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.18 001304592.1_48729001_3 - 8.3e-27 93.8 45.1 8.3e-27 93.8 45.1 2.5 2 0 0 2 2 2 1 Furin-like cysteine rich region fn3 PF00041.19 001304592.1_48729001_3 - 1.2e-15 57.5 8.1 5.2e-05 23.4 0.1 5.1 4 1 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.3 001304592.1_48729001_3 - 0.00038 20.8 5.2 0.02 15.3 1.6 3.7 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Y_Y_Y PF07495.11 001304592.1_48729001_3 - 0.034 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Y_Y_Y domain B2 PF11473.6 001304592.1_48729001_3 - 0.037 13.7 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding protein B2 Baculo_11_kDa PF06143.9 001304592.1_48729001_3 - 0.13 11.7 2.1 0.42 10.1 2.1 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family Glycophorin_A PF01102.16 001304592.1_48729001_3 - 0.51 10.5 1.8 1.5 8.9 1.8 1.7 1 0 0 1 1 1 0 Glycophorin A Gcw_chp PF09694.8 001319648.1_48726001_1 - 4.4e-12 46.4 0.0 3.6 7.4 0.0 7.5 8 0 0 8 8 8 6 Bacterial protein of unknown function (Gcw_chp) Minor_capsid_2 PF11114.6 001319648.1_48726001_1 - 2.1e-09 37.3 0.6 16 5.4 0.0 6.5 7 0 0 7 7 7 5 Minor capsid protein IL7 PF01415.14 001319648.1_48726001_2 - 0.0072 16.3 13.0 13 5.8 0.1 5.7 6 0 0 6 6 6 3 Interleukin 7/9 family MetJ PF01340.18 001319648.1_48726001_2 - 0.062 13.2 4.9 14 5.6 0.1 4.2 4 0 0 4 4 4 0 Met Apo-repressor, MetJ La PF05383.15 001319648.1_48726001_2 - 0.81 9.7 11.4 48 4.0 0.1 5.6 7 0 0 7 7 7 0 La domain SapB_1 PF05184.13 001319648.1_48726001_2 - 3.6 7.6 7.7 3.3e+02 1.3 0.0 5.3 6 0 0 6 6 6 0 Saposin-like type B, region 1 HH_signal PF01085.16 001323786.1_36423001_1 - 1.7e-82 274.7 0.0 2.4e-82 274.2 0.0 1.2 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Hint PF01079.18 001323786.1_36423001_1 - 5.1e-60 202.5 0.0 6.9e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Hint module Peptidase_M15_3 PF08291.9 001323786.1_36423001_1 - 0.00083 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M15 Intein_splicing PF14890.4 001323786.1_36423001_1 - 0.0039 16.5 0.0 0.0094 15.2 0.0 1.5 1 1 0 1 1 1 1 Intein splicing domain Ribosomal_S6e PF01092.17 001323786.1_36423001_1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S6e CBM_14 PF01607.22 001280947.1_26521001_1 - 0.00032 20.7 1.4 0.00037 20.5 0.6 1.6 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Alpha-amylase PF00128.22 027631.1_34224120_3 - 1.7e-82 277.6 1.0 2.2e-82 277.2 0.5 1.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain 2-oxogl_dehyd_N PF16078.3 027631.1_34224120_3 - 0.067 12.7 3.4 0.12 11.9 1.6 2.3 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus CAP PF00188.24 001311234.1_49322001_3 - 9.8e-18 65.1 2.6 1.5e-17 64.5 2.6 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family 7tm_6 PF02949.18 001312668.1_01923001_1 - 5.6e-26 91.2 13.0 8.3e-26 90.7 13.0 1.2 1 0 0 1 1 1 1 7tm Odorant receptor GST_N_3 PF13417.4 001304986.1_04822001_3 - 8.9e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001304986.1_04822001_3 - 5.2e-11 42.6 0.0 8.7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001304986.1_04822001_3 - 3.7e-09 36.5 0.0 7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001304986.1_04822001_3 - 1.1e-08 35.0 0.0 2.2e-08 34.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001304986.1_04822001_3 - 3.1e-07 30.5 0.0 7.2e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001304986.1_04822001_3 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ANF_receptor PF01094.26 001304975.1_04828001_1 - 1.8e-43 148.9 2.6 1.2e-40 139.6 2.6 2.2 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001304975.1_04828001_1 - 7.6e-38 129.6 0.4 1.3e-37 128.8 0.4 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001304975.1_04828001_1 - 6.7e-29 100.3 0.0 3.9e-28 97.8 0.0 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001304975.1_04828001_1 - 6.6e-20 71.4 0.0 2.1e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 CaM_bdg_C0 PF10562.7 001304975.1_04828001_1 - 3.7e-15 55.5 5.9 1.2e-14 53.9 5.9 1.9 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Ion_trans_2 PF07885.14 001304975.1_04828001_1 - 0.032 14.1 1.0 0.068 13.0 1.0 1.5 1 0 0 1 1 1 0 Ion channel 7tm_1 PF00001.19 001304973.1_04824001_1 - 7.5e-57 192.5 6.9 7.5e-57 192.5 6.9 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001304973.1_04824001_1 - 3.9e-05 23.0 6.3 3.9e-05 23.0 6.3 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001304973.1_04824001_1 - 0.0012 18.5 0.2 0.0012 18.5 0.2 2.1 3 0 0 3 3 3 1 Olfactory receptor RRM_1 PF00076.20 001319783.1_04823001_1 - 3.7e-21 74.6 0.0 7.4e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001319783.1_04823001_1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF1049 PF06305.9 001319783.1_04823001_2 - 1.9 8.2 4.2 6.1 6.6 4.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) p450 PF00067.20 001304728.1_04824001_2 - 9.2e-83 278.4 1.3 1.1e-82 278.1 1.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1977 PF09320.9 001319785.1_04823001_1 - 9.6e-30 102.8 0.5 3e-29 101.2 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.29 001319785.1_04823001_1 - 3.6e-23 81.3 1.0 7.2e-23 80.4 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF793 PF05633.9 001319785.1_04823001_1 - 0.034 13.0 0.2 0.052 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF793) TPR_2 PF07719.15 001319785.1_04823001_1 - 0.051 13.6 0.3 0.57 10.3 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.11 001319785.1_04823001_1 - 0.76 9.9 2.6 0.66 10.0 0.2 2.0 2 0 0 2 2 2 0 HemY protein N-terminus GST_N_3 PF13417.4 001319784.1_04822001_1 - 3.2e-13 49.7 0.0 7.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001319784.1_04822001_1 - 4.9e-12 45.9 0.0 9.8e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001319784.1_04822001_1 - 2.4e-08 33.9 0.1 5.3e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001319784.1_04822001_1 - 4.8e-08 33.1 0.0 8.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001319784.1_04822001_1 - 8.6e-08 32.2 0.6 1.5e-07 31.4 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001319784.1_04822001_1 - 2.5e-06 27.2 0.0 4.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Trehalase PF01204.16 001304977.1_04825001_1 - 1.9e-175 584.4 4.6 2.2e-175 584.2 4.6 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.12 001304977.1_04825001_1 - 3e-09 36.2 3.6 5.7e-09 35.2 3.6 1.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_63 PF03200.14 001304977.1_04825001_1 - 6.4e-06 25.1 0.6 0.00095 17.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Bac_rhamnosid PF05592.9 001304977.1_04825001_1 - 0.022 13.1 0.0 0.043 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Augurin PF15187.4 001304977.1_04825001_1 - 0.091 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 zf-C4 PF00105.16 001286877.1_33326001_3 - 1.6e-23 82.8 13.4 4.2e-23 81.4 13.4 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001286877.1_33326001_3 - 7.8e-11 41.8 0.6 2.1e-10 40.4 0.6 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.3 001286877.1_33326001_3 - 0.0024 17.8 10.0 0.0067 16.4 10.0 1.8 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type P4Ha_N PF08336.9 001286877.1_33326001_3 - 0.082 12.8 0.2 11 5.8 0.0 3.0 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SseC PF04888.10 001286877.1_33326001_3 - 0.32 10.3 2.7 1.6 8.0 0.1 2.7 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family DUF2318 PF10080.7 001286877.1_33326001_3 - 1.8 8.6 7.2 10 6.2 5.9 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Neur_chan_LBD PF02931.21 001308989.1_33324001_2 - 7.8e-77 257.4 0.2 1e-76 257.0 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001308989.1_33324001_2 - 9.7e-58 195.9 0.4 1.3e-57 195.5 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Tetraspannin PF00335.18 001308989.1_33324001_2 - 0.016 14.9 0.1 0.016 14.9 0.1 1.9 2 0 0 2 2 2 0 Tetraspanin family 7tm_7 PF08395.10 001286899.1_33324001_1 - 1.5e-37 129.6 25.8 1.9e-37 129.2 25.8 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor HLH PF00010.24 001279270.1_01723001_1 - 3.8e-19 68.3 0.5 6.2e-19 67.6 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hormone_recep PF00104.28 001279292.1_01726001_1 - 6.1e-22 78.1 0.0 1e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001279292.1_01726001_1 - 1.3e-15 57.4 18.9 2.4e-15 56.6 18.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Pellino PF04710.12 001279293.1_01724001_3 - 2.3e-130 434.8 0.0 2.8e-130 434.5 0.0 1.0 1 0 0 1 1 1 1 Pellino zf-RING_UBOX PF13445.4 001279293.1_01724001_3 - 0.00041 20.2 0.2 0.028 14.3 0.1 2.8 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.4 001279293.1_01724001_3 - 0.0049 16.6 12.1 0.094 12.5 0.1 3.1 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.4 001279293.1_01724001_3 - 0.0086 16.2 5.6 0.092 12.9 0.2 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.4 001279293.1_01724001_3 - 0.06 13.4 0.0 0.06 13.4 0.0 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.10 001279293.1_01724001_3 - 0.067 12.4 1.1 0.58 9.3 0.0 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4_2 PF13923.4 001279293.1_01724001_3 - 0.073 12.8 0.2 0.073 12.8 0.2 3.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001279293.1_01724001_3 - 0.08 12.8 0.1 0.08 12.8 0.1 2.8 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001279293.1_01724001_3 - 1.7 8.4 8.9 1.2 8.9 0.1 3.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EGF PF00008.25 001308630.1_01724001_1 - 1.2e-20 73.3 122.8 4.7e-08 33.1 6.5 9.4 8 1 0 8 8 8 4 EGF-like domain DSL PF01414.17 001308630.1_01724001_1 - 8.8e-12 44.9 6.0 8.8e-12 44.9 6.0 6.4 4 2 2 6 6 6 1 Delta serrate ligand hEGF PF12661.5 001308630.1_01724001_1 - 5.7e-09 36.2 18.0 9.6e-06 26.0 4.9 11.1 10 3 2 12 12 12 5 Human growth factor-like EGF EGF_2 PF07974.11 001308630.1_01724001_1 - 0.00024 21.3 25.1 0.001 19.2 8.4 10.4 10 1 1 11 11 11 7 EGF-like domain EGF_CA PF07645.13 001308630.1_01724001_1 - 0.00062 19.8 24.3 0.0024 17.9 10.4 9.2 4 3 6 10 10 10 3 Calcium-binding EGF domain EGF_3 PF12947.5 001308630.1_01724001_1 - 0.0025 17.8 7.0 0.0025 17.8 7.0 9.5 7 3 2 9 9 9 3 EGF domain EGF_MSP1_1 PF12946.5 001308630.1_01724001_1 - 0.011 15.6 6.9 0.011 15.6 6.9 8.4 7 1 1 8 8 8 0 MSP1 EGF domain 1 ECSCR PF15820.3 001308630.1_01724001_1 - 0.068 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Arm PF00514.21 001305246.1_01724001_1 - 4.7e-20 70.8 22.3 0.0098 15.8 0.0 9.6 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat KAP PF05804.10 001305246.1_01724001_1 - 6.4e-07 27.8 9.0 0.0031 15.6 2.7 2.7 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) Atx10homo_assoc PF09759.7 001305246.1_01724001_1 - 0.00024 21.0 7.0 0.017 15.1 0.7 3.5 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.4 001305246.1_01724001_1 - 0.026 14.9 0.9 2.2 8.7 0.1 3.5 3 0 0 3 3 3 0 HEAT-like repeat N1221 PF07923.11 001305246.1_01724001_1 - 0.037 13.1 0.1 0.095 11.8 0.1 1.6 1 0 0 1 1 1 0 N1221-like protein TIR_2 PF13676.4 001279297.1_01724001_1 - 2.9e-17 62.7 0.0 5.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001279297.1_01724001_1 - 2e-12 47.1 0.1 3.3e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.4 001279297.1_01724001_1 - 6.7e-11 42.5 4.8 8.9e-09 35.7 1.6 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001279297.1_01724001_1 - 3.7e-09 36.4 0.0 1.4e-07 31.3 0.1 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.4 001279297.1_01724001_1 - 1e-08 35.2 2.6 2.5e-07 30.8 0.5 2.7 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001279297.1_01724001_1 - 1.2e-05 25.3 4.4 4.1e-05 23.5 1.9 2.7 2 0 0 2 2 2 1 Immunoglobulin domain DUF1863 PF08937.9 001279297.1_01724001_1 - 0.0008 19.6 0.0 0.0099 16.1 0.0 2.2 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) V-set PF07686.15 001279297.1_01724001_1 - 0.0011 19.0 1.5 0.052 13.6 1.5 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain SIT PF15330.4 001279297.1_01724001_1 - 0.0013 19.0 0.4 0.0048 17.2 0.1 2.0 1 1 1 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT HemY_N PF07219.11 001279297.1_01724001_1 - 0.029 14.4 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TMEM154 PF15102.4 001279297.1_01724001_1 - 0.043 13.6 0.1 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF3382 PF11862.6 001279297.1_01724001_1 - 0.055 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) EphA2_TM PF14575.4 001279297.1_01724001_1 - 0.092 13.4 0.0 0.36 11.5 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TIR-like PF10137.7 001279297.1_01724001_1 - 0.099 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Forkhead PF00250.16 001308622.1_01724001_2 - 8.8e-34 115.6 0.1 2.3e-33 114.2 0.1 1.8 1 0 0 1 1 1 1 Forkhead domain Parvo_coat_N PF08398.8 001308622.1_01724001_2 - 0.15 12.1 0.5 0.33 11.0 0.5 1.5 1 0 0 1 1 1 0 Parvovirus coat protein VP1 DIX PF00778.15 001279313.1_01725001_1 - 1.1e-29 102.0 0.2 3.4e-29 100.4 0.2 1.9 1 0 0 1 1 1 1 DIX domain PDZ PF00595.22 001279313.1_01725001_1 - 3.4e-15 56.0 0.3 7.5e-15 54.9 0.3 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DEP PF00610.19 001279313.1_01725001_1 - 4.6e-15 55.3 0.1 1.2e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled PF02377.13 001279313.1_01725001_1 - 0.0011 19.3 26.1 0.0011 19.3 26.1 3.1 2 1 0 2 2 2 1 Dishevelled specific domain Shufflon_N PF04917.10 001279313.1_01725001_1 - 0.0066 15.8 0.2 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 Bacterial shufflon protein, N-terminal constant region PDZ_2 PF13180.4 001279313.1_01725001_1 - 0.029 14.5 0.5 0.08 13.1 0.2 1.9 2 0 0 2 2 2 0 PDZ domain Baculo_ME53 PF06061.9 001279313.1_01725001_1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 FAM76 PF16046.3 001279313.1_01725001_1 - 0.49 9.6 6.2 1 8.5 6.2 1.5 1 0 0 1 1 1 0 FAM76 protein EGF PF00008.25 001279299.1_01729001_1 - 3.8e-31 106.9 270.9 6.1e-07 29.5 9.6 17.2 18 0 0 18 18 18 11 EGF-like domain Ank_2 PF12796.5 001279299.1_01729001_1 - 4.8e-31 107.1 3.3 3.1e-12 46.8 0.2 4.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001279299.1_01729001_1 - 1.9e-27 95.1 0.8 2.4e-09 37.4 0.0 5.9 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.28 001279299.1_01729001_1 - 3.5e-23 80.8 5.0 3.9e-05 23.8 0.1 9.0 8 1 1 9 9 9 4 Ankyrin repeat Ank_3 PF13606.4 001279299.1_01729001_1 - 1.5e-22 77.1 1.3 0.0012 19.0 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.4 001279299.1_01729001_1 - 1.9e-19 69.3 6.0 2.5e-07 30.7 0.4 6.1 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Notch PF00066.15 001279299.1_01729001_1 - 1.7e-18 66.6 40.0 1.5e-10 41.2 12.0 10.4 10 3 1 11 11 11 3 LNR domain hEGF PF12661.5 001279299.1_01729001_1 - 1.5e-15 57.1 219.2 6.5e-06 26.5 6.1 19.4 18 1 1 19 19 19 10 Human growth factor-like EGF EGF_CA PF07645.13 001279299.1_01729001_1 - 1.4e-08 34.7 29.3 4.8e-06 26.5 7.3 15.6 8 5 8 16 16 16 3 Calcium-binding EGF domain EGF_2 PF07974.11 001279299.1_01729001_1 - 0.00055 20.1 270.2 0.055 13.7 10.5 17.1 15 2 2 17 17 17 11 EGF-like domain Frizzled PF01534.15 001279273.1_01724001_1 - 1.3e-96 323.3 19.8 2e-96 322.7 19.8 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.20 001279273.1_01724001_1 - 2.1e-08 34.7 6.0 3.7e-08 33.9 6.0 1.4 1 0 0 1 1 1 1 Fz domain 7tm_1 PF00001.19 001279273.1_01724001_1 - 0.96 8.5 19.9 0.57 9.2 12.5 2.8 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) PDR_CDR PF06422.10 001279273.1_01724001_1 - 1.1 9.1 3.6 35 4.3 3.6 2.8 1 1 0 1 1 1 0 CDR ABC transporter PIRT PF15099.4 001279273.1_01724001_1 - 4.1 6.9 9.1 0.16 11.4 0.3 2.9 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family wnt PF00110.17 001279275.1_01723001_1 - 5.9e-86 288.6 17.7 7.8e-86 288.2 17.7 1.2 1 0 0 1 1 1 1 wnt family Pr_beta_C PF12465.6 001279275.1_01723001_3 - 0.16 11.2 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Proteasome beta subunits C terminal wnt PF00110.17 001305252.1_01723001_1 - 1.9e-65 221.3 34.6 2.3e-65 221.0 34.6 1.0 1 0 0 1 1 1 1 wnt family Phage_Mu_Gp45 PF06890.10 001305252.1_01723001_1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein Homeobox PF00046.27 001305255.1_01725001_3 - 5.3e-38 128.5 11.1 5e-19 67.7 1.7 2.6 2 0 0 2 2 2 2 Homeobox domain Homeobox_KN PF05920.9 001305255.1_01725001_3 - 5.7e-07 29.2 0.2 0.05 13.4 0.0 2.6 2 0 0 2 2 2 2 Homeobox KN domain Homez PF11569.6 001305255.1_01725001_3 - 2.9e-06 26.5 0.5 0.04 13.2 0.1 2.7 2 0 0 2 2 2 2 Homeodomain leucine-zipper encoding, Homez HTH_28 PF13518.4 001305255.1_01725001_3 - 0.00052 20.0 0.3 0.61 10.1 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain YdaS_antitoxin PF15943.3 001305255.1_01725001_3 - 0.0038 16.9 0.1 3.9 7.3 0.0 2.4 2 0 0 2 2 2 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.20 001305255.1_01725001_3 - 0.14 12.1 0.1 20 5.2 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix T-box PF00907.20 001308629.1_01724001_1 - 3.7e-55 186.9 0.0 5e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 T-box DSL PF01414.17 001279282.1_01724001_1 - 8.7e-12 44.9 9.0 8.7e-12 44.9 9.0 4.7 4 1 0 4 4 4 1 Delta serrate ligand Rifin_STEVOR PF02009.14 001279282.1_01724001_1 - 0.0033 17.2 3.1 0.0033 17.2 3.1 2.8 3 0 0 3 3 3 1 Rifin/stevor family DUF1180 PF06679.10 001279282.1_01724001_1 - 0.0055 17.0 0.4 0.0096 16.2 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) CD225 PF04505.10 001279282.1_01724001_1 - 0.053 13.5 1.1 0.38 10.8 0.1 3.0 3 0 0 3 3 3 0 Interferon-induced transmembrane protein Bac_export_3 PF01313.17 001279282.1_01724001_1 - 6.7 6.6 7.8 29 4.5 0.0 3.8 4 0 0 4 4 4 0 Bacterial export proteins, family 3 Orn_Arg_deC_N PF02784.14 001286891.1_33323001_3 - 8.4e-80 267.6 0.0 1e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001286891.1_33323001_3 - 4.2e-28 97.5 0.0 1.1e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Amidase_2 PF01510.23 001287227.1_33322001_1 - 9.6e-24 84.0 1.5 2.4e-22 79.5 1.1 2.0 2 0 0 2 2 2 2 N-acetylmuramoyl-L-alanine amidase Tyrosinase PF00264.18 001305292.1_14025001_3 - 1.9e-25 90.4 1.2 5e-23 82.4 0.5 2.8 2 1 0 2 2 2 1 Common central domain of tyrosinase Tubulin PF00091.23 001305363.1_14024001_2 - 2.5e-67 226.8 0.0 3.7e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001305363.1_14024001_2 - 3.5e-42 143.5 0.1 5.2e-42 142.9 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001305363.1_14024001_2 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001305363.1_14024001_2 - 0.016 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.4 001305363.1_14024001_2 - 0.024 13.7 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin like An_peroxidase PF03098.13 001305289.1_14025001_1 - 2.3e-48 164.9 0.0 3.6e-45 154.4 0.0 2.6 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.25 001305289.1_14025001_1 - 0.029 14.5 13.3 0.069 13.3 13.3 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.11 001305289.1_14025001_1 - 5.1 7.4 19.1 0.81 10.0 15.1 1.8 2 0 0 2 2 2 0 EGF-like domain HSF_DNA-bind PF00447.15 001305377.1_14027001_3 - 3.8e-32 110.6 0.8 7e-32 109.8 0.8 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Vert_HS_TF PF06546.9 001305377.1_14027001_3 - 5.1e-08 32.8 4.4 9e-08 31.9 4.4 1.3 1 0 0 1 1 1 1 Vertebrate heat shock transcription factor LXG PF04740.10 001305377.1_14027001_3 - 0.27 10.8 4.0 0.52 9.8 4.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily LPP PF04728.11 001305377.1_14027001_3 - 1.5 9.1 3.8 8.8 6.7 0.4 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Carb_anhydrase PF00194.19 001305309.1_14024001_1 - 7.3e-52 176.3 0.3 2.4e-33 115.6 0.2 2.2 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase NID PF07292.11 001305309.1_14024001_1 - 0.079 13.5 0.0 0.24 12.0 0.0 1.7 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) Catalase PF00199.17 001305381.2_14024001_2 - 2.3e-195 649.0 0.1 2.8e-195 648.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.10 001305381.2_14024001_2 - 1.9e-17 63.0 0.1 5.4e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive PHD PF00628.27 001305368.2_14024001_1 - 0.052 13.3 1.1 0.14 12.0 1.1 1.6 1 0 0 1 1 1 0 PHD-finger p450 PF00067.20 001305368.2_14024001_3 - 4.9e-86 289.2 0.0 6e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cpn60_TCP1 PF00118.22 001317412.1_04825001_3 - 1.7e-86 290.7 15.0 5.4e-86 289.0 15.0 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aminotran_1_2 PF00155.19 001317412.1_04825001_3 - 0.043 12.8 0.0 0.68 8.9 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class I and II MannoseP_isomer PF01050.16 001317412.1_04825001_3 - 0.12 12.1 0.7 1.6 8.5 0.2 2.5 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase Pkinase PF00069.23 214631.1_49429001_3 - 1.8e-51 174.9 0.0 2.5e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 214631.1_49429001_3 - 3.6e-23 82.0 0.0 6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 214631.1_49429001_3 - 0.096 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TIR_2 PF13676.4 001329188.1_16823001_1 - 9.4e-07 29.0 0.0 1.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001329188.1_16823001_1 - 2.1e-06 27.5 0.0 3.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 TIR domain GST_C_3 PF14497.4 001304612.1_48723001_1 - 2e-22 79.1 0.3 2e-22 79.1 0.3 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001304612.1_48723001_1 - 9.1e-12 45.0 0.1 2.2e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001304612.1_48723001_1 - 3e-10 40.1 0.1 3e-10 40.1 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001304612.1_48723001_1 - 8.9e-07 28.6 0.0 2.1e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001304612.1_48723001_1 - 3.1e-05 24.1 0.0 7.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.2 001304612.1_48723001_1 - 0.0025 18.4 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.4 001304612.1_48723001_1 - 0.0082 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.7 001304612.1_48723001_1 - 0.04 14.0 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein PBP_GOBP PF01395.20 001279387.1_10522001_1 - 6.8e-14 51.9 0.3 1e-13 51.3 0.3 1.3 1 0 0 1 1 1 1 PBP/GOBP family PBP_GOBP PF01395.20 001308409.1_10522001_2 - 5.3e-14 52.2 1.2 6.8e-14 51.9 1.2 1.2 1 0 0 1 1 1 1 PBP/GOBP family ATP-synt_C PF00137.19 001304606.1_48722001_2 - 2.2e-37 127.1 38.3 4.2e-22 78.1 14.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Filament PF00038.19 001204724.1_03227001_1 - 7.7e-40 137.3 42.7 2.5e-23 83.0 30.9 2.2 1 1 1 2 2 2 2 Intermediate filament protein ATG16 PF08614.9 001204724.1_03227001_1 - 0.00013 22.1 35.8 0.047 13.7 15.5 3.0 2 1 0 2 2 2 2 Autophagy protein 16 (ATG16) LTD PF00932.17 001204724.1_03227001_1 - 0.00028 21.1 0.6 0.0006 20.0 0.6 1.5 1 0 0 1 1 1 1 Lamin Tail Domain HOOK PF05622.10 001204724.1_03227001_1 - 0.00037 18.7 10.3 0.00037 18.7 10.3 2.6 2 1 0 2 2 2 1 HOOK protein IncA PF04156.12 001204724.1_03227001_1 - 0.00043 20.0 39.8 0.054 13.1 8.8 3.4 2 1 1 3 3 3 2 IncA protein DUF3450 PF11932.6 001204724.1_03227001_1 - 0.00082 18.6 30.4 0.0056 15.9 1.3 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.6 001204724.1_03227001_1 - 0.00095 19.2 32.9 0.42 10.7 8.7 4.5 2 2 2 4 4 4 3 TATA element modulatory factor 1 TATA binding FPP PF05911.9 001204724.1_03227001_1 - 0.0035 15.5 34.8 0.023 12.8 13.1 2.1 1 1 1 2 2 2 1 Filament-like plant protein, long coiled-coil HAP1_N PF04849.11 001204724.1_03227001_1 - 0.0036 16.4 14.6 0.0036 16.4 14.6 2.7 2 1 1 3 3 3 1 HAP1 N-terminal conserved region HIP1_clath_bdg PF16515.3 001204724.1_03227001_1 - 0.0055 17.2 4.9 0.0055 17.2 4.9 5.1 2 2 3 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.9 001204724.1_03227001_1 - 0.0062 15.3 41.9 0.0052 15.6 13.2 3.2 1 1 1 3 3 3 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.10 001204724.1_03227001_1 - 0.016 15.2 41.2 0.47 10.4 16.0 3.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.9 001204724.1_03227001_1 - 0.021 15.1 12.9 1 9.7 0.1 5.7 2 2 3 6 6 5 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.10 001204724.1_03227001_1 - 0.058 12.7 12.6 1.2 8.3 5.3 3.0 2 1 2 4 4 4 0 Reovirus sigma C capsid protein MscS_porin PF12795.5 001204724.1_03227001_1 - 0.058 12.8 36.1 0.028 13.8 12.6 2.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain GAS PF13851.4 001204724.1_03227001_1 - 0.069 12.4 38.6 0.2 10.9 3.9 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding ERM PF00769.17 001204724.1_03227001_1 - 0.082 12.6 34.7 0.29 10.8 12.5 3.2 2 1 2 4 4 4 0 Ezrin/radixin/moesin family Phage_GP20 PF06810.9 001204724.1_03227001_1 - 0.22 11.2 25.5 0.19 11.4 4.0 3.9 2 2 2 4 4 4 0 Phage minor structural protein GP20 CCDC144C PF14915.4 001204724.1_03227001_1 - 0.32 9.9 35.0 0.31 10.0 10.3 2.4 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region HsbA PF12296.6 001204724.1_03227001_1 - 0.38 11.1 3.9 4.8 7.5 2.8 2.7 2 1 0 2 2 2 0 Hydrophobic surface binding protein A HMMR_N PF15905.3 001204724.1_03227001_1 - 0.83 8.9 34.9 0.15 11.4 4.5 3.2 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.4 001204724.1_03227001_1 - 1.7 7.8 31.0 18 4.4 12.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.6 001204724.1_03227001_1 - 1.7 8.5 32.9 0.083 12.8 0.9 4.2 2 2 1 4 4 4 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.13 001204724.1_03227001_1 - 3.6 7.8 36.4 0.82 10.0 7.0 3.4 1 1 2 3 3 3 0 Fez1 Lectin_N PF03954.12 001204724.1_03227001_1 - 4.9 6.8 20.3 0.77 9.4 5.5 4.1 3 1 2 5 5 4 0 Hepatic lectin, N-terminal domain APG6 PF04111.10 001204724.1_03227001_1 - 5 6.3 43.0 2.2 7.5 7.4 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 Baculo_PEP_C PF04513.10 001204724.1_03227001_1 - 6.3 6.7 15.2 4.7 7.1 5.8 3.5 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.7 001204724.1_03227001_1 - 7 5.5 28.6 2 7.3 9.2 2.9 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.4 001204724.1_03227001_1 - 7.9 5.9 35.5 0.59 9.6 11.4 3.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.10 001204724.1_03227001_1 - 7.9 6.3 16.4 3.4 7.5 0.2 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DUF2203 PF09969.7 001204724.1_03227001_1 - 9.4 6.8 20.0 14 6.3 0.0 4.4 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) FA_desaturase PF00487.22 001280889.2_06124001_2 - 9.7e-13 48.4 14.3 9.7e-13 48.4 14.3 1.9 1 1 1 2 2 2 1 Fatty acid desaturase MRJP PF03022.14 001328479.1_02824001_1 - 2.7e-93 312.3 9.8 2.7e-93 312.3 9.8 1.7 2 0 0 2 2 2 1 Major royal jelly protein Arrestin_N PF00339.27 001314081.1_28524001_2 - 1.5e-30 106.1 0.1 1.4e-26 93.2 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 001314081.1_28524001_2 - 5.1e-19 68.8 0.2 5.1e-18 65.6 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MRJP PF03022.14 001328480.1_02824001_1 - 7.7e-109 363.3 25.0 9.3e-103 343.4 5.5 2.7 1 1 1 3 3 3 2 Major royal jelly protein Insulin PF00049.16 001308866.1_14024001_3 - 3.1e-06 27.9 2.6 1.4e-05 25.9 2.6 2.1 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Jas PF16135.3 001308866.1_14024001_3 - 0.0076 16.3 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 TPL-binding domain in jasmonate signalling Peptidase_C1 PF00112.21 001311273.1_05723001_3 - 2.9e-63 213.7 8.2 3.9e-63 213.4 8.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.11 001311273.1_05723001_3 - 1.7e-10 40.4 0.0 3.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.13 001311273.1_05723001_3 - 0.009 14.7 2.9 0.044 12.4 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Bax1-I PF01027.18 001308885.1_14024001_1 - 2 8.1 9.9 51 3.5 1.0 4.1 1 1 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 Trypsin PF00089.24 001167658.1_51222001_1 - 4.1e-52 177.1 0.1 4.6e-52 176.9 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001167658.1_51222001_1 - 0.0003 21.6 3.1 0.00083 20.1 3.1 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001167658.1_51222001_1 - 0.0043 17.3 0.0 0.0075 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) S4 PF01479.23 001309100.2_42622001_1 - 1.6e-10 40.4 1.3 4.8e-10 38.9 1.3 1.9 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.17 001309100.2_42622001_1 - 3.7e-06 27.7 0.9 7.5e-06 26.7 0.5 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF4381 PF14316.4 001309100.2_42622001_1 - 0.063 13.4 0.8 0.092 12.9 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) BCDHK_Adom3 PF10436.7 001114643.2_06229001_1 - 2.7e-49 166.9 0.0 4.4e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.24 001114643.2_06229001_1 - 9.5e-12 45.3 0.0 1.7e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PID PF00640.21 167239.4_18529001_1 - 2.9e-44 150.4 0.0 1.1e-43 148.5 0.0 2.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.22 167239.4_18529001_1 - 1.4e-23 82.9 2.3 1.1e-10 41.6 0.4 2.9 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) Pkinase PF00069.23 170659.2_18529001_3 - 1.6e-50 171.8 0.0 2.4e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 170659.2_18529001_3 - 8.6e-24 84.1 0.0 1.3e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Hjc PF01870.16 170659.2_18529001_3 - 0.065 13.1 0.1 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) Trp_dioxygenase PF03301.11 078558.3_18523001_3 - 8.5e-161 534.9 2.1 1e-160 534.7 2.1 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase PXB PF12828.5 078558.3_18523001_3 - 0.081 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 PX-associated Glyco_hydro_31 PF01055.24 001297976.1_18526001_3 - 2.9e-34 118.9 0.0 2.7e-33 115.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 PDCD9 PF07147.10 079582.5_18523001_3 - 1.5e-06 27.6 0.9 2.6e-06 26.8 0.4 1.6 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) PK PF00224.19 142773.1_18526001_3 - 7.7e-151 501.7 1.3 1.1e-150 501.2 1.3 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.14 142773.1_18526001_3 - 3.3e-13 49.8 0.1 3.3e-13 49.8 0.1 2.9 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain DUF3775 PF12616.6 001170063.1_18525001_2 - 0.64 9.9 4.6 2.6 8.0 3.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3775) CDP-OH_P_transf PF01066.19 001276040.1_18523001_1 - 1.3e-14 54.5 0.3 4e-14 53.0 0.3 1.9 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Sugar_tr PF00083.22 001260205.1_18526001_3 - 1.9e-28 99.4 17.5 3.6e-28 98.5 17.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001260205.1_18526001_3 - 6e-22 77.9 27.8 5.6e-12 45.1 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cylicin_N PF15241.4 074039.1_18523120_3 - 0.067 13.3 0.5 0.067 13.3 0.5 2.1 2 0 0 2 2 2 0 Cylicin N-terminus Lipocalin PF00061.21 001274009.2_18523001_3 - 7.3e-10 39.1 0.0 1.5e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.10 001274009.2_18523001_3 - 5.4e-05 23.1 0.0 0.00042 20.2 0.0 2.1 2 0 0 2 2 2 1 Lipocalin-like domain Triabin PF03973.11 001274009.2_18523001_3 - 0.0029 17.4 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Triabin zf-LITAF-like PF10601.7 001259537.2_18526001_1 - 1.4e-15 57.2 20.1 1.4e-15 57.2 20.1 2.5 3 0 0 3 3 3 1 LITAF-like zinc ribbon domain zf-LITAF-like PF10601.7 001259537.2_18526001_2 - 5.1e-35 119.4 50.2 6e-22 77.6 15.8 2.5 2 0 0 2 2 2 2 LITAF-like zinc ribbon domain BAR PF03114.16 001273991.1_18525001_1 - 3.7e-34 118.3 6.2 5.2e-34 117.8 6.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.26 001273991.1_18525001_1 - 9.2e-10 37.8 0.9 1.2e-06 27.8 0.9 2.5 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 001273991.1_18525001_1 - 5.2e-09 35.7 0.1 1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 001273991.1_18525001_1 - 0.0001 21.8 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AhpC-TSA_2 PF13911.4 001273991.1_18525001_1 - 0.047 13.7 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Arfaptin PF06456.11 001273991.1_18525001_1 - 0.053 12.9 5.5 0.11 11.9 5.5 1.5 1 1 0 1 1 1 0 Arfaptin-like domain TUDOR PF00567.22 057425.3_18529001_1 - 4.7e-229 746.5 28.8 8.8e-27 93.4 0.0 11.0 11 0 0 11 11 11 9 Tudor domain SMN PF06003.10 057425.3_18529001_1 - 2.1e-10 40.2 0.0 4.6e-06 26.0 0.1 6.6 7 1 0 8 8 8 3 Survival motor neuron protein (SMN) DUF4537 PF15057.4 057425.3_18529001_1 - 2.4e-09 37.1 1.2 2 8.3 0.0 6.6 7 0 0 7 7 7 3 Domain of unknown function (DUF4537) DUF1325 PF07039.9 057425.3_18529001_1 - 2.7e-06 27.4 0.0 0.44 10.5 0.0 4.9 5 0 0 5 5 5 2 SGF29 tudor-like domain Agenet PF05641.10 057425.3_18529001_1 - 0.0033 17.8 12.1 9.4 6.7 0.1 7.3 8 0 0 8 8 8 1 Agenet domain Tudor-knot PF11717.6 057425.3_18529001_1 - 0.059 13.1 0.1 16 5.4 0.0 4.0 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain DUF4558 PF15104.4 001202068.2_18521001_2 - 2.9e-07 30.5 0.2 4.6e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) PEPcase_2 PF14010.4 001202068.2_18521001_2 - 0.065 11.6 0.0 0.081 11.3 0.0 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase G-patch PF01585.21 001298859.1_18524001_1 - 2.6e-14 52.7 0.2 4.5e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 G-patch domain zf-CCCH PF00642.22 001298859.1_18524001_1 - 0.02 14.6 1.2 0.061 13.1 1.2 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) eIF-1a PF01176.17 164564.3_18522001_1 - 6e-19 67.5 0.1 8.7e-19 67.0 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TAFH PF07531.12 048013.1_18523120_3 - 0.041 13.8 0.1 0.083 12.8 0.1 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF Peptidase_M14 PF00246.22 168213.3_18523001_1 - 2.3e-80 270.4 0.1 2.6e-80 270.2 0.1 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.14 168213.3_18523001_1 - 0.0022 18.2 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide adh_short PF00106.23 144416.2_18522001_3 - 6.8e-41 139.7 0.0 9.4e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 144416.2_18522001_3 - 5.6e-22 78.3 0.0 8.5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 144416.2_18522001_3 - 1.6e-06 28.0 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.17 144416.2_18522001_3 - 5.5e-05 22.2 0.3 8.2e-05 21.6 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family LMBR1 PF04791.14 001275094.1_18523001_2 - 0.55 8.9 9.1 0.79 8.4 9.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.10 001275094.1_18523001_2 - 3.6 5.9 7.1 4.6 5.5 7.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.10 001275094.1_18523001_2 - 3.9 6.6 8.0 4.1 6.6 0.9 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SSP160 PF06933.9 168751.3_18521001_2 - 0.0018 16.4 18.6 0.002 16.3 18.6 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF4834 PF16118.3 168751.3_18521001_2 - 0.016 16.0 3.0 0.02 15.7 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2448 PF10476.7 168751.3_18521001_2 - 0.087 12.6 7.2 0.12 12.1 7.2 1.4 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Mucin PF01456.15 168751.3_18521001_2 - 0.11 12.4 27.5 0.15 12.0 27.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Lamp PF01299.15 168751.3_18521001_2 - 0.14 11.6 13.2 0.17 11.2 13.2 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Sar8_2 PF03058.12 168751.3_18521001_2 - 0.23 11.9 3.1 0.32 11.4 3.1 1.3 1 1 0 1 1 1 0 Sar8.2 family NAM-associated PF14303.4 168751.3_18521001_2 - 1.3 9.5 6.4 1.6 9.2 6.4 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain FSA_C PF10479.7 168751.3_18521001_2 - 1.5 6.7 13.4 1.6 6.7 13.4 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Med3 PF11593.6 168751.3_18521001_2 - 3.1 6.7 16.6 4 6.4 16.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MGC-24 PF05283.9 168751.3_18521001_2 - 6.1 7.2 16.8 8.4 6.7 16.8 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Dicty_REP PF05086.10 168751.3_18521001_2 - 6.9 4.4 11.6 7.9 4.2 11.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FH2 PF02181.21 001014571.1_18529001_1 - 2.1e-80 270.5 1.1 3.5e-80 269.8 1.1 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.14 001014571.1_18529001_1 - 1.9e-21 76.5 0.1 5.7e-21 74.9 0.1 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.11 001014571.1_18529001_1 - 0.0001 21.8 0.0 0.00032 20.2 0.0 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain IBB PF01749.18 001014571.1_18529001_1 - 0.00014 22.0 1.2 0.00014 22.0 1.2 3.7 3 0 0 3 3 3 1 Importin beta binding domain S10_plectin PF03501.13 001305369.2_14022001_2 - 1.9e-47 159.2 0.2 2.3e-47 158.9 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF4719 PF15843.3 001305369.2_14022001_2 - 0.6 10.1 3.7 0.77 9.7 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) RNHCP PF12647.5 001280843.1_03224001_1 - 0.13 12.2 5.2 0.25 11.2 5.2 1.4 1 0 0 1 1 1 0 RNHCP domain Neur_chan_LBD PF02931.21 001280843.1_03224001_2 - 2.5e-67 226.4 1.8 3.2e-67 226.0 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001280843.1_03224001_2 - 1.3e-35 123.5 4.9 4.4e-35 121.7 4.9 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1772 PF08592.9 001280843.1_03224001_2 - 0.017 15.3 0.7 1.4 9.1 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) 7tm_6 PF02949.18 001280843.1_03224001_2 - 0.11 11.4 4.9 0.2 10.6 0.0 2.4 2 0 0 2 2 2 0 7tm Odorant receptor DUF3681 PF12442.6 001280843.1_03224001_2 - 0.12 12.9 0.1 0.31 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) EF-hand_7 PF13499.4 214604.1_49422001_1 - 9.9e-28 96.3 0.2 1.4e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 214604.1_49422001_1 - 4.8e-27 91.3 1.7 5.6e-07 28.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 214604.1_49422001_1 - 1.2e-20 71.4 0.2 3.1e-06 26.6 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.4 214604.1_49422001_1 - 1.6e-19 68.3 4.2 3.2e-07 29.4 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.4 214604.1_49422001_1 - 5e-17 61.3 2.6 6e-09 35.4 0.0 3.4 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.7 214604.1_49422001_1 - 3.7e-05 23.9 0.0 0.011 15.9 0.0 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.4 214604.1_49422001_1 - 0.00094 19.3 0.0 0.054 13.7 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain Transcrip_reg PF01709.18 214604.1_49422001_1 - 0.0065 15.8 0.4 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Transcriptional regulator Sigma70_r1_1 PF03979.12 214604.1_49422001_1 - 0.0077 16.1 0.3 0.51 10.3 0.2 2.2 2 0 0 2 2 2 1 Sigma-70 factor, region 1.1 DUF1456 PF07308.11 214604.1_49422001_1 - 0.025 14.8 0.2 3.6 7.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Phage_TAC_6 PF09550.8 214604.1_49422001_1 - 0.037 14.3 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC DUF1840 PF08895.9 214604.1_49422001_1 - 0.064 13.5 0.3 0.67 10.2 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) Excalibur PF05901.9 214604.1_49422001_1 - 0.18 12.3 0.3 81 3.8 0.0 3.3 3 0 0 3 3 3 0 Excalibur calcium-binding domain Spt20 PF12090.6 001204539.1_03223001_1 - 0.0055 16.2 5.5 0.0078 15.7 5.5 1.2 1 0 0 1 1 1 1 Spt20 family Vps54 PF07928.10 001204539.1_03223001_1 - 0.29 11.5 2.1 0.45 10.8 2.1 1.3 1 0 0 1 1 1 0 Vps54-like protein EF-hand_7 PF13499.4 001204539.1_03223001_3 - 9.1e-23 80.4 9.0 2.4e-16 59.8 1.8 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001204539.1_03223001_3 - 2.4e-21 73.5 12.5 1.6e-07 30.2 0.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.4 001204539.1_03223001_3 - 3.3e-18 63.9 11.1 1.2e-05 24.7 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.4 001204539.1_03223001_3 - 8.1e-14 50.3 11.6 4.9e-05 22.5 0.2 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.4 001204539.1_03223001_3 - 3.3e-12 45.8 6.0 1.7e-05 24.3 0.7 3.6 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001204539.1_03223001_3 - 0.0015 18.7 2.9 0.14 12.4 0.6 3.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001204539.1_03223001_3 - 0.038 13.8 5.0 2.6 7.9 0.2 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001204539.1_03223001_3 - 0.1 12.8 0.2 2.5 8.4 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain Caleosin PF05042.11 001204539.1_03223001_3 - 0.14 12.0 2.0 20 4.9 0.0 2.9 2 1 0 2 2 2 0 Caleosin related protein DUF3439 PF11921.6 001204539.1_03223001_3 - 0.47 10.3 9.6 0.74 9.7 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glycoprotein PF03409.13 001204539.1_03223001_3 - 0.49 9.0 3.9 0.69 8.6 3.9 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein FSA_C PF10479.7 001204539.1_03223001_3 - 0.53 8.2 2.7 0.66 7.9 2.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Arm PF00514.21 001286895.1_33325001_1 - 9.2e-48 158.8 24.6 4.1e-09 36.0 0.2 11.2 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.18 001286895.1_33325001_1 - 2e-09 36.5 9.1 5.4e-08 31.7 2.4 3.2 2 1 1 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.5 001286895.1_33325001_1 - 2.5e-09 37.2 5.0 0.00054 19.9 0.7 4.7 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.4 001286895.1_33325001_1 - 1.6e-06 28.3 11.5 0.0025 18.0 1.1 5.0 4 1 1 5 5 4 1 HEAT repeats HEAT_EZ PF13513.4 001286895.1_33325001_1 - 3.5e-06 27.2 10.9 1.5 9.2 0.6 6.1 4 2 2 6 6 6 3 HEAT-like repeat HEAT PF02985.20 001286895.1_33325001_1 - 1.8e-05 24.4 7.1 0.74 10.1 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat KAP PF05804.10 001286895.1_33325001_1 - 4.1e-05 21.8 2.0 0.011 13.8 0.3 2.9 3 0 0 3 3 3 2 Kinesin-associated protein (KAP) DUF3361 PF11841.6 001286895.1_33325001_1 - 5.4e-05 23.1 4.3 2.1 8.1 0.0 4.8 2 1 3 5 5 5 2 Domain of unknown function (DUF3361) Arm_2 PF04826.11 001286895.1_33325001_1 - 0.00025 20.5 9.7 0.0069 15.7 0.1 3.9 3 2 0 4 4 4 2 Armadillo-like V-ATPase_H_N PF03224.12 001286895.1_33325001_1 - 0.0012 18.1 3.8 0.57 9.3 0.9 3.9 2 2 0 3 3 3 1 V-ATPase subunit H Atx10homo_assoc PF09759.7 001286895.1_33325001_1 - 0.0014 18.6 2.2 0.037 14.0 0.2 3.8 3 2 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Neurochondrin PF05536.9 001286895.1_33325001_1 - 0.27 9.4 5.2 0.19 9.9 0.6 2.7 3 0 0 3 3 3 0 Neurochondrin RIX1 PF08167.10 001286895.1_33325001_1 - 0.34 10.5 3.4 0.47 10.0 0.4 2.6 2 2 0 2 2 2 0 rRNA processing/ribosome biogenesis RasGEF_N_2 PF14663.4 001286895.1_33325001_1 - 0.95 9.7 5.5 16 5.8 0.3 4.5 3 2 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain V-ATPase_H_C PF11698.6 001286895.1_33325001_1 - 1.2 9.1 4.6 1.6e+02 2.3 0.0 4.4 2 1 3 6 6 6 0 V-ATPase subunit H EF-hand_1 PF00036.30 001204580.1_03223001_2 - 1e-40 134.1 10.7 2.3e-09 36.0 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001204580.1_03223001_2 - 1.1e-34 118.6 2.9 1.4e-17 63.8 0.8 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001204580.1_03223001_2 - 1.4e-31 107.9 10.5 3.4e-15 55.4 0.6 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001204580.1_03223001_2 - 5.1e-28 94.5 6.9 4.3e-09 35.5 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001204580.1_03223001_2 - 5.6e-26 88.7 8.4 1.4e-06 27.5 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001204580.1_03223001_2 - 2.1e-14 53.5 0.2 1.3e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001204580.1_03223001_2 - 4.8e-09 36.0 0.2 0.00024 20.9 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001204580.1_03223001_2 - 5e-07 29.9 0.1 0.039 14.1 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001204580.1_03223001_2 - 2.9e-05 24.8 0.0 0.0038 17.9 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.11 001204580.1_03223001_2 - 0.00038 20.3 0.0 0.16 11.9 0.0 2.9 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.8 001204580.1_03223001_2 - 0.00088 19.2 0.5 0.0027 17.6 0.1 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.9 001204580.1_03223001_2 - 0.0059 16.1 2.5 0.0081 15.7 2.5 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF4497 PF14924.4 001204580.1_03223001_2 - 0.0079 16.5 0.0 6.3 7.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.14 001204580.1_03223001_2 - 0.029 14.6 0.3 5.7 7.2 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF3349 PF11829.6 001204580.1_03223001_2 - 0.034 14.8 0.3 5.3 7.8 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Caleosin PF05042.11 001204580.1_03223001_2 - 0.053 13.3 1.0 1.6 8.5 0.1 3.1 2 1 0 2 2 1 0 Caleosin related protein DUF2267 PF10025.7 001204580.1_03223001_2 - 0.069 13.3 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) dCache_2 PF08269.9 001204580.1_03223001_2 - 0.076 12.0 0.2 8.1 5.4 0.0 2.2 1 1 1 2 2 2 0 Cache domain TerB PF05099.11 001204580.1_03223001_2 - 0.098 12.5 0.5 3.7 7.4 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB GPHH PF16905.3 001204580.1_03223001_2 - 0.1 12.3 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Chorion_S16 PF05836.10 001308414.1_10522001_1 - 6.6e-31 106.6 0.8 6.6e-31 106.6 0.8 1.4 1 1 0 1 1 1 1 Chorion protein S16 Peptidase_C41 PF05417.9 001308414.1_10522001_1 - 0.12 12.1 0.4 0.16 11.6 0.4 1.2 1 0 0 1 1 1 0 Hepatitis E cysteine protease p450 PF00067.20 001319836.1_10525001_3 - 3.7e-79 266.5 3.4 4.6e-79 266.2 3.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001319832.1_10524001_1 - 3.7e-71 240.1 0.0 4.8e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001319833.1_10524001_1 - 5.8e-73 246.1 0.0 7.5e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_1 PF00036.30 001319833.1_10524001_1 - 0.06 12.8 0.1 0.2 11.2 0.1 2.0 1 0 0 1 1 1 0 EF hand COesterase PF00135.26 001320386.1_10524001_1 - 4.6e-112 375.4 0.0 5.5e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001320386.1_10524001_1 - 0.00031 20.5 0.1 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001320386.1_10524001_1 - 0.048 13.0 0.2 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.6 001320386.1_10524001_1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.5 001320386.1_10524001_1 - 0.15 12.6 0.0 0.49 10.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Homeobox PF00046.27 001308540.1_04224001_1 - 1.4e-20 72.8 4.1 2.2e-20 72.1 4.1 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001308540.1_04224001_1 - 0.021 14.6 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain EHN PF06441.10 001308546.1_04224001_3 - 1.1e-29 102.8 0.0 1.8e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.18 001308546.1_04224001_3 - 9e-14 51.6 0.1 1.8e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001308546.1_04224001_3 - 0.0012 19.3 1.5 0.0027 18.2 1.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Vitellogenin_N PF01347.20 001308542.1_04229001_3 - 2.4e-240 799.1 29.6 4.3e-239 795.0 29.6 2.2 1 1 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.9 001308542.1_04229001_3 - 2.2e-43 148.6 2.1 2.2e-43 148.6 2.1 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1943) VWD PF00094.23 001308542.1_04229001_3 - 5e-17 62.5 1.3 7.9e-16 58.6 0.4 3.3 3 0 0 3 3 3 1 von Willebrand factor type D domain HEAT_2 PF13646.4 001308542.1_04229001_3 - 0.0013 18.9 0.1 0.0055 16.9 0.1 2.1 1 0 0 1 1 1 1 HEAT repeats SPX PF03105.17 001308542.1_04229001_3 - 0.0029 17.5 24.6 0.0029 17.5 24.6 3.4 3 0 0 3 3 3 1 SPX domain Phage_integrase PF00589.20 001308542.1_04229001_3 - 0.026 14.2 1.7 2 8.0 0.0 2.9 3 0 0 3 3 3 0 Phage integrase family COesterase PF00135.26 001308539.1_04225001_3 - 2.2e-131 439.2 0.0 2.5e-131 439.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001308539.1_04225001_3 - 3.6e-07 30.1 0.0 6.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001308539.1_04225001_3 - 0.053 12.9 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family GTP_EFTU PF00009.25 001308543.1_04224001_1 - 2.8e-53 180.2 0.0 4.2e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001308543.1_04224001_1 - 2.7e-41 140.2 0.0 5.2e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001308543.1_04224001_1 - 5.9e-13 48.9 2.3 7.2e-13 48.6 0.4 2.2 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001308543.1_04224001_1 - 0.00087 19.2 0.1 0.024 14.6 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001308543.1_04224001_1 - 0.093 12.6 0.9 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Pkinase PF00069.23 001308545.1_04223001_1 - 1.1e-40 139.6 0.0 1.4e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001308545.1_04223001_1 - 1.4e-25 90.0 0.0 1.9e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.20 001308545.1_04223001_1 - 0.025 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.12 001308545.1_04223001_1 - 0.046 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001308545.1_04223001_1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Tsg PF04668.10 001308547.1_04222001_1 - 6.8e-58 195.0 3.5 6.8e-58 195.0 3.5 2.2 2 0 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region Ribosomal_L32e PF01655.16 001308544.1_04222001_3 - 2.4e-56 188.6 3.7 3.4e-56 188.1 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 Trypsin PF00089.24 001323337.1_43422001_1 - 2.9e-49 167.7 0.7 3.6e-49 167.4 0.7 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001323337.1_43422001_1 - 0.0003 21.6 0.0 0.00048 20.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001323337.1_43422001_1 - 0.017 15.4 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) TGFb_propeptide PF00688.16 214655.1_49427001_1 - 3e-40 138.4 0.0 4.2e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 214655.1_49427001_1 - 3.4e-34 117.7 1.1 6.1e-34 116.9 1.1 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain Histone PF00125.22 214541.1_49421001_1 - 5.5e-19 68.7 0.1 7.7e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 214541.1_49421001_1 - 9.7e-05 22.5 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.11 214541.1_49421001_1 - 0.0013 19.1 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.3 214541.1_49421001_1 - 0.047 13.6 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 YscO-like protein Ski_Sno PF02437.15 001323829.1_40729001_2 - 3.5e-35 119.9 0.0 5.8e-35 119.2 0.0 1.3 1 0 0 1 1 1 1 SKI/SNO/DAC family VWC PF00093.16 001323832.1_40728001_1 - 4e-38 129.4 82.0 1.3e-10 41.2 15.9 4.5 4 0 0 4 4 4 4 von Willebrand factor type C domain CHRD PF07452.10 001323832.1_40728001_1 - 3.5e-08 34.2 0.0 0.00067 20.5 0.0 3.7 4 0 0 4 4 4 2 CHRD domain TRAM1 PF08390.9 001323832.1_40728001_1 - 0.03 13.8 3.2 0.63 9.6 0.2 2.6 2 0 0 2 2 2 0 TRAM1-like protein Ephrin_rec_like PF07699.11 001323832.1_40728001_2 - 0.079 12.6 0.6 0.25 11.0 0.6 1.8 1 0 0 1 1 1 0 Putative ephrin-receptor like GATA PF00320.25 001323818.1_40725001_3 - 4.7e-29 99.6 20.7 2.3e-14 52.6 7.4 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.10 001323818.1_40725001_3 - 3.7e-05 23.0 8.7 0.035 13.5 0.7 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.8 001323818.1_40725001_3 - 0.021 14.8 2.0 3.1 7.9 0.1 3.0 2 0 0 2 2 2 0 Zinc ribbon domain DUF2387 PF09526.8 001323818.1_40725001_3 - 0.027 14.5 3.7 3.8 7.6 0.3 3.1 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.11 001323818.1_40725001_3 - 0.066 13.1 2.6 4.1 7.4 0.5 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Auto_anti-p27 PF06677.10 001323818.1_40725001_3 - 0.083 12.9 5.7 2 8.5 0.4 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.9 001323818.1_40725001_3 - 0.56 10.0 8.8 4.7 7.1 1.3 3.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.10 001323818.1_40725001_3 - 1 9.7 11.4 0.45 10.8 2.7 2.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.5 001323818.1_40725001_3 - 1.4 8.8 8.4 16 5.5 0.7 2.9 1 1 2 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.15 001323818.1_40725001_3 - 1.7 8.4 6.6 7.6 6.3 1.7 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Vps36-NZF-N PF16988.3 001323818.1_40725001_3 - 2 7.7 4.9 1.3 8.3 0.4 2.7 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain T-box PF00907.20 001323828.1_40724001_2 - 5.4e-81 271.1 0.4 9.4e-81 270.3 0.4 1.3 1 0 0 1 1 1 1 T-box PAS_3 PF08447.10 001323806.1_40726001_3 - 2.1e-23 82.3 0.4 1.7e-20 72.9 0.1 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001323806.1_40726001_3 - 3.5e-19 68.9 0.1 2.8e-15 56.3 0.2 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 001323806.1_40726001_3 - 2.7e-17 62.7 0.0 1.2e-10 41.3 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.5 001323806.1_40726001_3 - 1.2e-06 28.6 0.0 0.053 13.7 0.0 2.4 2 0 0 2 2 2 2 PAS domain HLH PF00010.24 001323806.1_40726001_3 - 0.00014 21.6 1.1 0.00033 20.4 1.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.8 001323806.1_40726001_3 - 0.00043 20.4 0.0 0.25 11.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold Macin PF14865.4 001204700.1_03222001_2 - 2.7e-11 43.7 10.1 5.2e-11 42.8 10.1 1.5 1 0 0 1 1 1 1 Macin EGF PF00008.25 001204700.1_03222001_2 - 8.8 6.6 8.6 13 6.1 5.7 2.5 2 1 0 2 2 2 0 EGF-like domain TraB PF01963.15 001279279.1_01724001_1 - 2.3e-52 178.4 0.0 2.9e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 TraB family Gp_dh_C PF02800.18 001137324.1_53724001_2 - 3.6e-70 234.5 0.0 6.3e-70 233.7 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001137324.1_53724001_2 - 2.4e-37 127.2 0.1 6.4e-37 125.8 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001137324.1_53724001_2 - 0.0085 16.1 0.0 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.17 001137324.1_53724001_2 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ada_Zn_binding PF02805.14 001137324.1_53724001_2 - 0.12 12.3 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 Metal binding domain of Ada ARID PF01388.19 001136890.1_53726001_3 - 2.2e-14 53.7 0.1 4.9e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.27 001136890.1_53726001_3 - 0.0008 19.1 7.0 0.0008 19.1 7.0 2.4 2 0 0 2 2 2 1 PHD-finger peroxidase PF00141.21 001155342.1_53723001_3 - 1.6e-70 237.2 0.0 2.1e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Toxin_30 PF08117.9 001155342.1_53723001_3 - 0.049 13.8 0.6 0.15 12.2 0.6 1.9 1 0 0 1 1 1 0 Ptu family Tom22 PF04281.11 001148291.1_53725001_3 - 0.0057 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Pkinase_Tyr PF07714.15 145324.1_53722120_1 - 5.5e-27 94.5 0.0 6.8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 145324.1_53722120_1 - 2.2e-17 63.1 0.0 2.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CDC50 PF03381.13 001138238.1_53723001_3 - 2.7e-88 295.9 0.2 3.6e-88 295.5 0.2 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Ribosomal_L11_N PF03946.12 001143350.1_53722001_3 - 1.3e-22 79.1 0.1 2.3e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.17 001143350.1_53722001_3 - 2.2e-18 66.4 0.3 4.5e-18 65.4 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_S30 PF04758.12 001155851.1_53722001_1 - 4.3e-30 103.6 9.5 6.6e-30 103.0 9.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_L24e PF01246.18 001279089.1_12222001_3 - 2.4e-28 98.0 0.8 2.4e-28 98.0 0.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Spore_coat_CotO PF14153.4 001279089.1_12222001_3 - 1.5 8.6 10.2 2.1 8.1 10.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FBD PF08387.8 001151131.1_53724001_2 - 1.7e-10 40.4 0.0 8.6e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 FBD F-box PF00646.31 001151131.1_53724001_2 - 0.00012 21.7 0.4 0.00038 20.1 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001151131.1_53724001_2 - 0.043 13.6 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 F-box-like MFS_2 PF13347.4 001149119.1_53725001_1 - 6e-15 54.6 27.7 7.9e-15 54.2 27.7 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein DUF2127 PF09900.7 001149119.1_53725001_1 - 0.034 14.3 0.4 0.034 14.3 0.4 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2127) Synaptobrevin PF00957.19 001147086.1_53723001_2 - 2.1e-29 101.0 2.0 3.1e-29 100.5 2.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.4 001147086.1_53723001_2 - 3.3e-22 78.2 0.0 5.1e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain PRT_C PF08372.8 001147086.1_53723001_2 - 0.046 13.3 1.4 0.068 12.8 1.4 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal LETM1 PF07766.11 001195906.1_53726001_2 - 6.9e-110 366.4 4.8 6.9e-110 366.4 4.8 2.5 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.4 001195906.1_53726001_2 - 1.5e-06 28.4 1.5 4.2e-05 23.8 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.30 001195906.1_53726001_2 - 0.0012 18.1 0.0 0.017 14.5 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.4 001195906.1_53726001_2 - 0.0018 17.9 0.0 0.1 12.4 0.0 3.2 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.4 001195906.1_53726001_2 - 0.037 13.4 0.0 0.15 11.5 0.0 2.1 1 0 0 1 1 1 0 EF hand DUF3474 PF11960.6 001319690.1_47924001_2 - 3e-54 182.6 0.0 5.5e-54 181.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.22 001319690.1_47924001_2 - 2.1e-30 106.3 22.7 3.3e-30 105.6 22.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Hum_adeno_E3A PF05393.9 001319690.1_47924001_2 - 0.052 13.4 0.8 0.13 12.2 0.8 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein NPR1_like_C PF12313.6 001323837.1_03823001_1 - 4.8e-76 254.7 9.2 7.9e-76 254.0 9.2 1.4 1 0 0 1 1 1 1 NPR1/NIM1 like defence protein C terminal Ank_2 PF12796.5 001323837.1_03823001_1 - 8.5e-14 51.8 3.2 5e-08 33.3 0.6 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001323837.1_03823001_1 - 1.8e-10 40.7 1.4 2.4e-08 34.0 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3420 PF11900.6 001323837.1_03823001_1 - 2e-10 40.5 2.0 7.5e-10 38.7 0.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3420) Ank PF00023.28 001323837.1_03823001_1 - 3.3e-08 33.5 0.9 0.012 15.9 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.4 001323837.1_03823001_1 - 3.9e-08 33.5 3.1 0.00022 21.6 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.4 001323837.1_03823001_1 - 4.9e-08 32.5 0.3 0.014 15.7 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeat PIN_6 PF17146.2 001323837.1_03823001_1 - 0.0063 16.9 0.4 0.022 15.1 0.4 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease TMEM156 PF15106.4 001323837.1_03823001_1 - 0.019 14.3 0.3 0.038 13.3 0.3 1.5 1 0 0 1 1 1 0 TMEM156 protein family FMN_red PF03358.13 001155230.2_53722001_3 - 1.3e-34 119.1 0.0 1.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.15 001155230.2_53722001_3 - 4.4e-06 26.4 0.0 7.4e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold peroxidase PF00141.21 001302602.1_35123001_2 - 3.1e-79 265.8 0.0 3.8e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Retro_M PF02813.12 001302602.1_35123001_2 - 0.082 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Retroviral M domain DUF4677 PF15726.3 001302602.1_35123001_2 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) TAXi_N PF14543.4 001137052.2_53723001_3 - 3.3e-48 164.1 4.1 6.5e-48 163.2 3.6 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.4 001137052.2_53723001_3 - 9.4e-29 100.1 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.21 001137052.2_53723001_3 - 2.5e-16 59.9 0.0 1.3e-14 54.2 0.0 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease RXLR PF16810.3 001137052.2_53723001_3 - 0.016 15.5 0.8 0.024 15.0 0.8 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity zf-RNPHF PF08080.10 001137052.2_53723001_3 - 1.6 8.6 7.6 2 8.3 0.3 3.3 3 0 0 3 3 3 0 RNPHF zinc finger Steroid_dh PF02544.14 001327551.1_24422001_1 - 1.5e-54 183.9 1.6 1.5e-54 183.9 1.6 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.10 001327551.1_24422001_1 - 3.8e-08 33.0 1.6 3.8e-08 33.0 1.6 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1295) PEMT PF04191.11 001327551.1_24422001_1 - 5.1e-05 23.5 1.9 0.00022 21.4 1.9 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase PCO_ADO PF07847.10 001155983.1_53724001_1 - 4.1e-68 228.7 0.0 5.2e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO AP2 PF00847.18 001159194.1_53722001_2 - 6.7e-12 45.4 4.1 1.1e-11 44.6 4.1 1.4 1 0 0 1 1 1 1 AP2 domain Kelch_6 PF13964.4 001281266.1_53023001_1 - 2e-10 40.4 4.5 1e-06 28.7 0.0 4.8 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.23 001281266.1_53023001_1 - 2.4e-06 26.9 0.4 0.0016 17.9 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.13 001281266.1_53023001_1 - 8e-05 22.3 0.7 0.00027 20.6 0.1 2.3 2 0 0 2 2 2 1 Kelch motif F-box PF00646.31 001281266.1_53023001_1 - 0.00011 21.9 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF1668 PF07893.11 001281266.1_53023001_1 - 0.0027 17.0 0.9 0.0027 17.0 0.9 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1668) Kelch_3 PF13415.4 001281266.1_53023001_1 - 0.021 15.0 1.2 8.9 6.6 0.0 3.5 3 1 0 3 3 3 0 Galactose oxidase, central domain F-box-like PF12937.5 001281266.1_53023001_1 - 0.064 13.0 0.1 0.064 13.0 0.1 2.1 2 0 0 2 2 2 0 F-box-like Kelch_4 PF13418.4 001281266.1_53023001_1 - 0.11 12.3 0.6 29 4.6 0.1 3.2 3 1 0 3 3 3 0 Galactose oxidase, central domain Pkinase PF00069.23 001281201.1_53023001_1 - 1e-65 221.6 0.0 2.5e-65 220.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001281201.1_53023001_1 - 5e-33 114.4 0.0 7.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001281201.1_53023001_1 - 7e-19 67.6 0.0 1.7e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001281201.1_53023001_1 - 6e-09 35.5 0.0 2.9e-08 33.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001281201.1_53023001_1 - 0.0012 18.1 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PBP PF01161.18 001280022.1_22822001_1 - 2e-13 50.6 0.0 2.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.23 001281267.1_53023001_1 - 1.3e-74 250.7 0.0 1.7e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001281267.1_53023001_1 - 1.5e-41 142.3 0.0 2e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001281267.1_53023001_1 - 8e-23 80.2 0.2 1.4e-22 79.4 0.2 1.4 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001281267.1_53023001_1 - 7.7e-10 38.4 0.0 3.9e-08 32.8 0.0 2.2 1 1 0 2 2 2 1 Kinase-like APH PF01636.21 001281267.1_53023001_1 - 0.0088 15.9 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.12 001281267.1_53023001_1 - 0.024 13.9 0.0 0.053 12.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001281267.1_53023001_1 - 0.028 13.9 0.4 0.27 10.7 0.1 2.1 1 1 1 2 2 2 0 RIO1 family ABC1 PF03109.14 001281267.1_53023001_1 - 0.05 13.6 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 ABC1 family Hemagglutinin PF00509.16 001281267.1_53023001_1 - 0.076 11.3 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin GST_N PF02798.18 001281248.1_53022001_3 - 4.1e-19 68.6 0.1 6.8e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001281248.1_53022001_3 - 8.5e-16 58.0 0.1 1.4e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001281248.1_53022001_3 - 1.4e-12 47.6 0.0 2.2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001281248.1_53022001_3 - 9.7e-07 28.5 0.1 2.1e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001281248.1_53022001_3 - 1.5e-06 28.2 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.7 001281248.1_53022001_3 - 0.11 12.5 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Thaumatin PF00314.15 001281202.1_53022001_1 - 2.7e-60 203.7 16.6 3.2e-60 203.5 16.6 1.0 1 0 0 1 1 1 1 Thaumatin family Pico_P2A PF00947.17 001281202.1_53022001_1 - 0.007 16.3 0.9 0.015 15.2 0.9 1.6 1 0 0 1 1 1 1 Picornavirus core protein 2A Glyco_hydro_35 PF01301.17 001278975.1_12226001_2 - 6.6e-120 400.4 0.1 8.6e-120 400.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.13 001278975.1_12226001_2 - 5.4e-08 32.4 0.0 1.2e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.4 001278975.1_12226001_2 - 0.00016 22.1 0.2 0.83 10.1 0.1 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain SQS_PSY PF00494.17 001288886.1_12723001_1 - 2.6e-71 240.1 0.5 4e-71 239.5 0.5 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase AhpC-TSA_2 PF13911.4 001281032.1_53023001_1 - 4.4e-18 65.4 0.0 6.2e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.19 001281032.1_53023001_1 - 5.8e-07 29.3 0.0 8.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001281032.1_53023001_1 - 0.006 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin K-box PF01486.15 001281189.1_53022001_2 - 3.8e-27 94.2 11.2 9e-27 93.0 11.2 1.6 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001281189.1_53022001_2 - 9.7e-27 92.1 0.3 1.7e-26 91.3 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Vps51 PF08700.9 001281189.1_53022001_2 - 0.052 13.5 4.4 0.094 12.7 0.5 2.5 1 1 1 2 2 2 0 Vps51/Vps67 Tmpp129 PF10272.7 001281189.1_53022001_2 - 0.065 12.4 0.2 0.1 11.8 0.2 1.4 1 1 0 1 1 1 0 Putative transmembrane protein precursor TMF_DNA_bd PF12329.6 001281189.1_53022001_2 - 2.6 8.0 11.3 6.2 6.8 2.4 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding E2F_CC-MB PF16421.3 001281189.1_53022001_2 - 6.1 7.2 6.7 12 6.4 0.4 2.5 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain Myb_DNA-binding PF00249.29 001281062.1_53022001_1 - 4.8e-32 109.7 5.3 2e-15 56.5 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001281062.1_53022001_1 - 2.8e-20 72.2 1.4 9.5e-13 48.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001281062.1_53022001_1 - 0.047 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-binding PF00249.29 001281009.1_53022001_3 - 1.4e-33 114.6 1.7 1.2e-16 60.4 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001281009.1_53022001_3 - 4.5e-22 77.9 0.3 2.2e-12 46.9 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001281009.1_53022001_3 - 0.0048 16.8 0.0 0.93 9.4 0.0 2.5 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.3 001281009.1_53022001_3 - 0.024 14.4 0.0 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Myb DNA-binding like Rap1_C PF11626.6 001281009.1_53022001_3 - 0.1 12.6 1.1 0.92 9.5 1.1 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Terpene_synth_C PF03936.14 001280966.1_53024001_1 - 7e-90 300.9 0.1 4.9e-89 298.1 0.0 2.1 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001280966.1_53024001_1 - 5e-48 163.2 0.9 8.8e-48 162.4 0.9 1.3 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain Cupin_1 PF00190.20 001281199.1_53022001_1 - 1.9e-48 163.7 0.9 2.4e-48 163.4 0.9 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.9 001281199.1_53022001_1 - 6.3e-08 32.1 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.5 001281199.1_53022001_1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain Myb_DNA-binding PF00249.29 001281001.1_53023001_3 - 2.3e-31 107.6 4.5 4.6e-15 55.4 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001281001.1_53023001_3 - 1.3e-19 70.1 0.2 3.9e-11 42.9 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain P_C PF06640.9 001281001.1_53023001_3 - 0.005 17.0 0.8 0.005 17.0 0.8 1.8 2 0 0 2 2 2 1 P protein C-terminus SLIDE PF09111.8 001281001.1_53023001_3 - 0.026 14.4 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 SLIDE Myb_DNA-bind_5 PF13873.4 001281001.1_53023001_3 - 0.03 14.3 0.1 7.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain EPSP_synthase PF00275.18 001281247.1_53024001_1 - 2.2e-148 494.2 0.0 2.6e-148 494.0 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Tubulin PF00091.23 001302995.1_08323001_1 - 1.9e-69 233.7 0.0 3e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001302995.1_08323001_1 - 5.9e-41 139.5 0.3 8.9e-41 138.9 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.4 001302995.1_08323001_1 - 0.00059 19.0 0.1 0.002 17.2 0.0 1.8 2 0 0 2 2 2 1 Tubulin like Misat_Tub_SegII PF10644.7 001302995.1_08323001_1 - 0.00076 19.6 0.1 0.0025 18.0 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001302995.1_08323001_1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Uds1 PF15456.4 001301895.1_07128001_1 - 0.3 11.1 3.7 2.5 8.1 0.9 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DAD PF02109.14 001293917.1_29822001_3 - 1.3e-37 128.3 2.0 1.8e-37 127.9 2.0 1.2 1 0 0 1 1 1 1 DAD family HSP70 PF00012.18 001246851.2_48426001_2 - 4.7e-263 873.7 13.1 5.6e-263 873.5 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001246851.2_48426001_2 - 4.7e-20 71.5 1.0 1e-16 60.6 0.0 2.6 1 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.4 001246851.2_48426001_2 - 0.00069 19.9 2.8 0.17 12.2 0.0 3.2 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.18 001246851.2_48426001_2 - 0.0012 18.2 0.2 0.99 8.7 0.0 2.7 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.16 001246851.2_48426001_2 - 0.0053 15.9 0.8 0.39 9.8 0.1 2.9 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase PilM_2 PF11104.6 001246851.2_48426001_2 - 0.02 13.8 0.9 0.17 10.8 0.0 2.7 4 0 0 4 4 4 0 Type IV pilus assembly protein PilM; StbA PF06406.9 001246851.2_48426001_2 - 0.13 11.3 3.7 0.56 9.3 0.1 3.0 2 1 1 3 3 3 0 StbA protein ketoacyl-synt PF00109.24 001302971.1_08325001_3 - 7.8e-60 202.4 0.6 1.6e-59 201.5 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.20 001302971.1_08325001_3 - 1.7e-34 118.2 0.1 2.9e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.21 001302971.1_08325001_3 - 0.0087 15.3 0.3 0.018 14.3 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Cupin_1 PF00190.20 001302978.1_08324001_2 - 1.1e-72 242.5 1.5 9.8e-37 125.7 0.1 2.5 3 0 0 3 3 3 2 Cupin Cupin_2 PF07883.9 001302978.1_08324001_2 - 3e-06 26.7 0.0 0.025 14.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain E1-E2_ATPase PF00122.18 001302990.1_08325001_1 - 2.8e-52 177.1 2.8 2.8e-52 177.1 2.8 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.24 001302990.1_08325001_1 - 4.9e-35 121.6 0.0 9.3e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.10 001302990.1_08325001_1 - 0.012 15.2 1.2 0.22 11.1 0.4 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HMA PF00403.24 001302990.1_08325001_1 - 0.063 13.6 0.1 0.56 10.6 0.1 2.5 2 0 0 2 2 2 0 Heavy-metal-associated domain DUF2304 PF10066.7 001302990.1_08325001_1 - 3.6 7.7 7.0 0.24 11.5 1.3 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF4378 PF14309.4 001302982.1_08326001_1 - 2e-33 115.9 0.3 4.9e-33 114.6 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) VARLMGL PF14383.4 001302982.1_08326001_1 - 0.00022 20.5 0.0 0.00065 19.0 0.0 1.8 1 0 0 1 1 1 1 DUF761-associated sequence motif Stathmin PF00836.17 001302982.1_08326001_1 - 0.016 15.0 0.3 0.016 15.0 0.3 3.0 3 0 0 3 3 3 0 Stathmin family FA_desaturase PF00487.22 001305025.1_08323001_1 - 1.7e-33 116.4 18.7 2.3e-33 116.0 18.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.6 001305025.1_08323001_1 - 5.2e-06 26.6 0.1 9.5e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Acyl-ACP_TE PF01643.15 001302994.1_08323001_1 - 1.3e-80 270.1 0.0 4.6e-80 268.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-ACP thioesterase Acyl-thio_N PF12590.6 001302994.1_08323001_1 - 2.5e-55 186.4 0.3 4e-55 185.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-ATP thioesterase 4HBT_2 PF13279.4 001302994.1_08323001_1 - 9.5e-05 22.7 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 2 Thioesterase-like superfamily E1-E2_ATPase PF00122.18 001302988.1_08325001_1 - 5e-52 176.3 3.2 5e-52 176.3 3.2 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.24 001302988.1_08325001_1 - 7.1e-34 117.8 0.0 1.4e-33 116.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.10 001302988.1_08325001_1 - 0.017 14.7 0.8 0.27 10.8 0.4 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.4 001302988.1_08325001_1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Gate PF07670.12 001302988.1_08325001_1 - 1.3 9.2 7.9 2.4 8.3 0.2 3.1 2 1 1 3 3 3 0 Nucleoside recognition SecY PF00344.18 001302988.1_08325001_1 - 4.4 6.3 9.0 1.2 8.2 0.3 2.7 3 1 0 3 3 3 0 SecY translocase Spore_YabQ PF09578.8 001302988.1_08325001_1 - 8.3 6.6 7.0 1.7 8.8 2.8 2.0 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) E1-E2_ATPase PF00122.18 001302976.1_08326001_1 - 1.1e-58 198.1 0.1 2.1e-58 197.1 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.24 001302976.1_08326001_1 - 1.3e-42 146.3 2.5 2.5e-42 145.4 2.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.24 001302976.1_08326001_1 - 1.5e-10 41.2 0.0 7.2e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.10 001302976.1_08326001_1 - 2.9e-06 27.1 0.7 0.008 15.8 0.3 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase zf-CCHC PF00098.21 001319283.1_08322001_1 - 1.6e-36 122.6 55.6 2.2e-08 33.7 2.7 6.6 6 1 0 6 6 6 6 Zinc knuckle CSD PF00313.20 001319283.1_08322001_1 - 2.5e-23 81.6 0.1 4.8e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC_5 PF14787.4 001319283.1_08322001_1 - 9.2e-09 34.7 40.1 0.0021 17.6 2.2 6.2 5 1 1 6 6 6 5 GAG-polyprotein viral zinc-finger OB_RNB PF08206.9 001319283.1_08322001_1 - 0.0014 18.1 0.1 0.0038 16.7 0.1 1.7 1 1 0 1 1 1 1 Ribonuclease B OB domain zf-CCHC_3 PF13917.4 001319283.1_08322001_1 - 0.018 14.9 33.4 0.18 11.7 0.3 5.4 3 2 2 5 5 5 0 Zinc knuckle S1 PF00575.21 001319283.1_08322001_1 - 0.13 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain zf-CCHC_4 PF14392.4 001319283.1_08322001_1 - 0.27 10.8 44.3 0.14 11.7 1.5 5.9 6 0 0 6 6 6 0 Zinc knuckle E1-E2_ATPase PF00122.18 001302987.1_08326001_1 - 4.4e-54 183.0 0.6 7.7e-54 182.2 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.24 001302987.1_08326001_1 - 7.2e-36 124.3 0.1 1.3e-35 123.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.24 001302987.1_08326001_1 - 4.5e-09 36.5 0.7 1.7e-08 34.7 0.7 2.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.10 001302987.1_08326001_1 - 0.022 14.4 0.5 0.75 9.3 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UDPGT PF00201.16 001290241.1_53023001_1 - 7e-30 104.1 0.0 1.5e-29 103.0 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Cerato-platanin PF07249.10 001290241.1_53023001_1 - 0.065 13.2 0.4 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 Cerato-platanin Glyco_transf_10 PF00852.17 001317151.1_52925001_1 - 8e-34 116.8 0.0 1.2e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_trans_1_2 PF13524.4 001317151.1_52925001_1 - 0.047 14.0 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 2-Hacid_dh_C PF02826.17 001302985.1_08324001_1 - 4.6e-28 97.6 0.0 8.1e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SLAM PF06214.9 001302985.1_08324001_1 - 0.037 13.9 1.4 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein eIF3g PF12353.6 001302985.1_08324001_1 - 0.08 13.2 1.3 0.2 11.9 1.3 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Cyclin_N PF00134.21 001302989.1_08323001_1 - 4.3e-26 91.1 0.6 4.3e-26 91.1 0.6 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001302989.1_08323001_1 - 1e-15 57.8 0.0 2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Acyl-ACP_TE PF01643.15 001302983.1_08323001_1 - 3.1e-80 268.9 0.0 1.1e-79 267.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-ACP thioesterase Acyl-thio_N PF12590.6 001302983.1_08323001_1 - 1.9e-55 186.8 0.6 3e-55 186.2 0.6 1.3 1 0 0 1 1 1 1 Acyl-ATP thioesterase 4HBT_2 PF13279.4 001302983.1_08323001_1 - 3.3e-05 24.2 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 2 Thioesterase-like superfamily p450 PF00067.20 001302991.1_08323001_1 - 1.6e-58 198.5 0.0 2.2e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M90 PF06167.10 001302991.1_08323001_1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 2OG-FeII_Oxy PF03171.18 001293254.1_44323001_3 - 1.5e-27 95.9 0.0 2.4e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001293254.1_44323001_3 - 3.2e-13 50.4 0.0 5.5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal FA_desaturase PF00487.22 001318080.1_08323001_1 - 1.7e-33 116.4 18.7 2.3e-33 116.0 18.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.6 001318080.1_08323001_1 - 7e-06 26.2 0.1 1.3e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Abhydrolase_3 PF07859.11 104004.1_53024120_3 - 1e-55 188.7 0.0 1.3e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.26 104004.1_53024120_3 - 8.7e-06 24.8 0.1 1.7e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.5 104004.1_53024120_3 - 0.0014 17.5 0.0 0.0019 17.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.7 104004.1_53024120_3 - 0.007 15.1 0.0 0.017 13.9 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.6 104004.1_53024120_3 - 0.033 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chal_sti_synt_N PF00195.17 001328985.1_29824001_3 - 4.9e-126 418.5 0.1 6.6e-126 418.1 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.13 001328985.1_29824001_3 - 4e-72 241.0 0.0 6e-72 240.5 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.8 001328985.1_29824001_3 - 1.4e-07 31.1 0.0 3.5e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.8 001328985.1_29824001_3 - 2.6e-06 27.4 0.0 1.4e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.10 001328985.1_29824001_3 - 5.4e-06 25.8 0.0 6.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Mo-co_dimer PF03404.14 148411.1_53722120_2 - 1.1e-21 77.2 0.7 1.4e-21 76.9 0.7 1.1 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.18 148411.1_53722120_2 - 0.18 11.8 1.7 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 BNR/Asp-box repeat AUX_IAA PF02309.14 001317316.1_52923001_3 - 3.2e-59 200.6 1.8 3.4e-58 197.2 1.8 2.4 1 1 0 1 1 1 1 AUX/IAA family Aminotran_1_2 PF00155.19 001317147.1_52924001_1 - 1.5e-106 356.5 0.0 1.9e-106 356.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II AAA PF00004.27 001317275.1_52924001_3 - 3.3e-14 53.3 0.0 5.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.9 001317275.1_52924001_3 - 0.0033 17.4 0.1 0.0095 15.9 0.0 1.8 2 0 0 2 2 2 1 Torsin HSF_DNA-bind PF00447.15 148433.1_24124120_2 - 4e-29 100.9 1.4 7e-29 100.1 1.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding S36_mt PF10937.6 148433.1_24124120_2 - 0.012 17.0 0.2 0.024 16.1 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial HALZ PF02183.16 001353495.1_48523001_2 - 7.9e-18 64.3 5.0 1.8e-17 63.1 5.0 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper Homeobox PF00046.27 001353495.1_48523001_2 - 8.2e-15 54.2 2.7 1.6e-14 53.4 2.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001353495.1_48523001_2 - 6.2e-06 25.9 0.2 1.3e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF947 PF06102.10 001353495.1_48523001_2 - 0.0017 18.3 0.6 0.0017 18.3 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF947) DUF972 PF06156.11 001353495.1_48523001_2 - 0.039 14.4 0.1 0.039 14.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Kinetocho_Slk19 PF12709.5 001353495.1_48523001_2 - 0.64 10.4 7.2 0.074 13.4 1.0 2.4 2 0 0 2 2 2 0 Central kinetochore-associated HLH PF00010.24 001353580.1_24124001_2 - 1.2e-06 28.2 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RL11D PF11088.6 001353580.1_24124001_2 - 0.18 12.0 0.1 0.18 12.0 0.1 2.0 3 0 0 3 3 3 0 Glycoprotein encoding membrane proteins RL5A and RL6 Hid1 PF12722.5 001353580.1_24124001_2 - 1.9 6.4 6.9 2.6 5.9 6.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.6 001353580.1_24124001_2 - 5.6 5.5 6.9 7.8 5.1 6.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DDHD PF02862.15 001353580.1_24124001_2 - 9.5 6.1 12.8 11 5.9 11.8 1.4 1 1 0 1 1 1 0 DDHD domain AP2 PF00847.18 001305883.1_29823001_1 - 4.7e-13 49.0 0.1 8.4e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 AP2 domain Pkinase PF00069.23 001308367.1_43623001_1 - 7.9e-70 235.1 0.0 2e-69 233.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001308367.1_43623001_1 - 1.4e-38 132.6 0.0 2e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001308367.1_43623001_1 - 1.2e-17 63.7 0.0 3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001308367.1_43623001_1 - 6e-09 35.5 0.0 8.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001308367.1_43623001_1 - 0.00013 21.3 0.1 0.00029 20.1 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001308367.1_43623001_1 - 0.0072 15.8 0.1 0.019 14.5 0.1 1.5 1 1 1 2 2 2 1 RIO1 family APH PF01636.21 001308367.1_43623001_1 - 0.0082 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Gliadin PF13016.4 001304781.1_06623001_1 - 9.8e-27 93.1 26.8 9.8e-27 93.1 26.8 6.3 3 1 1 4 4 4 1 Cys-rich Gliadin N-terminal Tryp_alpha_amyl PF00234.20 001304781.1_06623001_1 - 1.2e-12 47.9 30.9 1.2e-12 47.9 30.9 6.4 2 2 1 3 3 3 2 Protease inhibitor/seed storage/LTP family DUF4148 PF13663.4 001304781.1_06623001_1 - 0.041 13.9 0.2 0.041 13.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) 14-3-3 PF00244.18 001255222.3_24123001_2 - 2.1e-105 351.0 6.0 3.6e-105 350.2 6.0 1.4 1 0 0 1 1 1 1 14-3-3 protein UDPGT PF00201.16 001155519.3_53724001_3 - 1.8e-26 92.9 0.0 2.8e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase RskA PF10099.7 001155519.3_53724001_3 - 1.9 8.6 6.5 3.9 7.6 3.1 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA G-gamma PF00631.20 149083.1_24122120_1 - 2e-09 37.2 0.1 4.2e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 GGL domain Myb_DNA-binding PF00249.29 001327822.1_53722001_1 - 1.3e-18 66.7 3.7 5.1e-12 45.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001327822.1_53722001_1 - 1.8e-07 31.2 1.2 2e-05 24.6 0.2 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001327822.1_53722001_1 - 0.00091 18.9 0.2 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like DUF911 PF06023.10 001327822.1_53722001_3 - 0.65 9.2 2.4 0.87 8.8 2.4 1.1 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) DUF4124 PF13511.4 001329439.1_53725001_2 - 0.84 9.8 6.9 1.7 8.8 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) Amino_oxidase PF01593.22 001329439.1_53725001_3 - 9.6e-90 301.9 0.0 1.2e-89 301.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001329439.1_53725001_3 - 5.2e-14 52.1 0.2 1.3e-13 50.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.22 001329439.1_53725001_3 - 4e-10 39.2 0.5 2.1e-06 26.9 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.12 001329439.1_53725001_3 - 3.1e-06 26.5 1.6 0.00068 18.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001329439.1_53725001_3 - 2.6e-05 23.4 0.0 0.0054 15.7 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.12 001329439.1_53725001_3 - 2.6e-05 23.0 1.4 0.0015 17.2 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.25 001329439.1_53725001_3 - 3.6e-05 24.1 1.1 0.0026 18.2 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001329439.1_53725001_3 - 0.00012 21.7 0.5 0.002 17.7 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.5 001329439.1_53725001_3 - 0.00053 19.3 0.1 0.00093 18.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.4 001329439.1_53725001_3 - 0.0027 16.9 0.3 0.17 11.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.4 001329439.1_53725001_3 - 0.0075 16.2 1.1 1.4 8.8 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.15 001329439.1_53725001_3 - 0.035 13.2 0.0 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.17 001329439.1_53725001_3 - 0.12 11.5 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.10 001329439.1_53725001_3 - 0.21 10.5 0.3 0.77 8.6 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Autophagy_act_C PF03987.13 131257.1_53723120_1 - 0.0024 18.3 1.5 0.0062 17.0 1.5 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_act_C PF03987.13 131257.1_53723120_2 - 4.2e-08 33.5 0.1 9.7e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Sterol_MT_C PF08498.8 001317553.2_24123001_3 - 1.2e-21 76.7 0.0 2.1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.10 001317553.2_24123001_3 - 3.6e-21 75.5 0.0 6.4e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001317553.2_24123001_3 - 6.9e-18 65.0 0.0 1.2e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001317553.2_24123001_3 - 6.4e-15 55.1 0.0 8.9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.18 001317553.2_24123001_3 - 1.1e-13 51.0 0.0 1.7e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.4 001317553.2_24123001_3 - 6.6e-11 42.3 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.16 001317553.2_24123001_3 - 2.5e-10 40.0 0.0 4.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.10 001317553.2_24123001_3 - 3.8e-09 37.0 0.0 7.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 001317553.2_24123001_3 - 0.0055 16.3 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.12 001317553.2_24123001_3 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.8 001317553.2_24123001_3 - 0.029 14.0 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.9 001317553.2_24123001_3 - 0.032 13.0 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.4 001317553.2_24123001_3 - 0.049 13.5 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.5 001317553.2_24123001_3 - 0.051 13.4 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.10 001317553.2_24123001_3 - 0.051 13.0 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.11 001317553.2_24123001_3 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.15 001317553.2_24123001_3 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase ICL PF00463.19 001323712.1_46325001_3 - 2.5e-277 920.4 1.3 2.9e-277 920.2 1.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.4 001323712.1_46325001_3 - 3.6e-10 39.6 0.0 6.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Proteasome PF00227.24 001325955.1_35223001_2 - 2.3e-55 186.9 0.0 2.9e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001325955.1_35223001_2 - 8.9e-16 57.1 0.1 1.6e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature C2 PF00168.28 001317559.2_24123001_2 - 2.2e-07 31.0 0.0 3.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain DOCK-C2 PF14429.4 001317559.2_24123001_2 - 0.0033 17.2 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins NT-C2 PF10358.7 001317559.2_24123001_2 - 0.026 14.1 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins HATPase_c PF02518.24 001297524.1_14825001_2 - 7.9e-32 110.0 0.0 1.5e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.22 001297524.1_14825001_2 - 6.7e-17 61.5 0.0 2.2e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.23 001297524.1_14825001_2 - 1.1e-16 60.4 2.0 1.1e-16 60.4 2.0 3.0 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain GAF PF01590.24 001297524.1_14825001_2 - 7.6e-14 52.3 0.1 1.9e-13 50.9 0.1 1.7 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.4 001297524.1_14825001_2 - 0.00053 20.2 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 GAF domain HATPase_c_3 PF13589.4 001297524.1_14825001_2 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3135 PF11333.6 001297524.1_14825001_2 - 0.14 12.3 1.6 2.2 8.5 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) Glyco_hydro_18 PF00704.26 001329829.1_52823001_3 - 2.6e-29 102.8 0.3 1.9e-28 100.0 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_16 PF00722.19 001329835.1_52823001_2 - 7.4e-59 198.1 1.8 7.4e-59 198.1 1.8 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 XET_C PF06955.10 001329835.1_52823001_2 - 2.4e-19 68.9 5.1 4.5e-19 68.0 5.1 1.5 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus Profilin PF00235.17 001301678.1_42021001_1 - 2.8e-44 150.3 0.0 3.1e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Profilin Phosphorylase PF00343.18 001288189.1_48626001_3 - 0 1011.4 0.0 0 1011.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase FA_desaturase PF00487.22 001323721.1_46323001_1 - 8.3e-32 110.9 15.2 1.1e-31 110.5 15.2 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.6 001323721.1_46323001_1 - 4.2e-07 30.1 0.0 7.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Pkinase PF00069.23 001315995.1_06923001_1 - 3.5e-70 236.2 0.0 4.6e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315995.1_06923001_1 - 4.7e-36 124.3 0.0 6.5e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315995.1_06923001_1 - 4.6e-18 65.0 0.1 1.1e-17 63.8 0.1 1.6 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315995.1_06923001_1 - 2.8e-09 36.6 0.0 1.2e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.12 001315995.1_06923001_1 - 0.0062 15.8 0.1 0.047 12.9 0.0 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.29 001316227.1_06922001_1 - 4.8e-34 116.1 3.8 1.9e-16 59.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316227.1_06922001_1 - 3.3e-18 65.6 0.8 6.7e-11 42.1 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001316227.1_06922001_1 - 0.026 14.4 0.4 0.098 12.6 0.0 2.1 3 0 0 3 3 3 0 SLIDE FAM219A PF15260.4 001316227.1_06922001_1 - 0.053 13.8 2.6 0.11 12.7 2.6 1.6 1 1 0 1 1 1 0 Protein family FAM219A IQCJ-SCHIP1 PF15157.4 001316227.1_06922001_1 - 0.19 11.5 3.2 0.17 11.6 1.5 1.7 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Oleosin PF01277.15 001316097.1_06924001_2 - 1.7e-12 47.0 12.4 1.7e-12 47.0 12.4 1.5 2 0 0 2 2 2 1 Oleosin DUF481 PF04338.10 001316097.1_06924001_3 - 0.11 12.4 1.1 6.1 6.7 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF481 Secretin PF00263.19 001316097.1_06924001_3 - 0.24 10.9 18.5 0.58 9.6 3.8 3.0 1 1 2 3 3 3 0 Bacterial type II and III secretion system protein DUF5020 PF16412.3 001316097.1_06924001_3 - 1.2 8.9 6.2 10 5.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5020) Phage_BR0599 PF09356.8 001316097.1_06924001_3 - 1.9 8.8 3.7 19 5.6 0.1 3.0 2 1 1 3 3 3 0 Phage conserved hypothetical protein BR0599 E1_DerP2_DerF2 PF02221.13 001316097.1_06924001_3 - 2.8 8.3 8.5 34 4.7 0.5 3.9 1 1 3 4 4 4 0 ML domain Glyco_hydro_2 PF00703.19 001316097.1_06924001_3 - 3.9 8.0 16.4 11 6.6 1.1 3.4 2 1 1 3 3 3 0 Glycosyl hydrolases family 2 Lipoxygenase PF00305.17 001328471.1_14826001_3 - 0 1036.9 0.0 0 1036.6 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001328471.1_14826001_3 - 6.4e-08 33.0 0.0 1.8e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain zf-C2H2_6 PF13912.4 001248734.2_24122001_2 - 7.9e-21 73.4 9.5 1.5e-10 40.6 2.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.4 001248734.2_24122001_2 - 1.7e-07 31.4 5.3 0.0092 16.6 0.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.24 001248734.2_24122001_2 - 0.00036 20.7 4.1 0.24 11.8 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 001248734.2_24122001_2 - 0.00098 19.2 1.9 0.0062 16.7 0.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.5 001248734.2_24122001_2 - 0.003 17.7 2.8 0.25 11.6 0.6 2.2 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_3 PF13878.4 001248734.2_24122001_2 - 0.007 16.0 1.0 3.1 7.6 0.5 2.7 2 0 0 2 2 2 2 zinc-finger of acetyl-transferase ESCO UPF0515 PF15135.4 001248734.2_24122001_2 - 0.04 13.2 0.4 0.066 12.5 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Zn-ribbon_8 PF09723.8 001248734.2_24122001_2 - 0.083 12.9 1.0 0.74 9.9 0.3 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.5 001248734.2_24122001_2 - 0.11 12.8 0.8 0.11 12.8 0.8 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type UPF0544 PF15749.3 001248734.2_24122001_2 - 0.18 12.4 3.7 1.4 9.5 2.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0544 zf-3CxxC_2 PF17180.2 001248734.2_24122001_2 - 0.25 12.0 3.5 0.46 11.1 3.5 1.4 1 0 0 1 1 1 0 Zinc-binding domain zf-C2HC_2 PF13913.4 001248734.2_24122001_2 - 0.3 10.9 3.9 1.5 8.7 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.4 001248734.2_24122001_2 - 0.3 11.5 9.7 2.7 8.5 0.6 3.7 3 1 0 3 3 3 0 Zinc-finger double domain zf-Mss51 PF13824.4 001248734.2_24122001_2 - 0.42 10.7 1.9 5.8 7.0 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_11 PF16622.3 001248734.2_24122001_2 - 0.71 9.5 6.4 5.3 6.8 1.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Redoxin PF08534.8 001302844.2_34422001_2 - 1.8e-32 111.9 0.0 2.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.19 001302844.2_34422001_2 - 3.4e-13 49.4 0.0 5.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Pkinase PF00069.23 001315854.1_06923001_1 - 2.5e-67 226.9 0.0 4.3e-67 226.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315854.1_06923001_1 - 4.7e-41 140.6 0.0 7.1e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315854.1_06923001_1 - 4e-15 55.6 0.2 8.1e-15 54.6 0.2 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315854.1_06923001_1 - 3.6e-08 32.9 0.0 6.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.20 001315854.1_06923001_1 - 2e-05 24.2 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.12 001315854.1_06923001_1 - 0.00017 20.9 0.1 0.00027 20.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001315854.1_06923001_1 - 0.0053 16.6 0.0 0.24 11.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Integrase_DNA PF02920.13 001315854.1_06923001_3 - 0.02 14.5 1.4 0.032 13.8 1.4 1.3 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Lipase_GDSL PF00657.20 001316006.1_06923001_1 - 5e-24 85.3 0.2 6.6e-24 84.9 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SRF-TF PF00319.16 001316034.1_06922001_1 - 1.1e-25 88.7 0.2 2e-25 87.9 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001316034.1_06922001_1 - 6.8e-16 58.1 12.7 1.3e-15 57.3 12.7 1.4 1 0 0 1 1 1 1 K-box region CO_dh PF02552.14 001316034.1_06922001_1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit PTS_IIA PF02255.14 001316034.1_06922001_1 - 0.11 12.4 0.7 6.5 6.7 0.2 2.6 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF2390 PF09523.8 001316034.1_06922001_1 - 4 7.7 8.1 1.3 9.3 2.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2390) Pkinase PF00069.23 001315872.1_06923001_1 - 3.1e-74 249.6 0.0 4e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315872.1_06923001_1 - 2.4e-40 138.3 0.0 3.4e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315872.1_06923001_1 - 1.5e-21 76.2 0.0 4e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315872.1_06923001_1 - 2.2e-09 36.9 0.0 9.6e-09 34.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001315872.1_06923001_1 - 0.0084 15.4 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lipoprotein_16 PF03923.11 001315872.1_06923001_1 - 0.074 12.6 0.0 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized lipoprotein APH PF01636.21 001315872.1_06923001_1 - 0.24 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Amino_oxidase PF01593.22 001316264.1_06924001_1 - 1.2e-79 268.6 0.0 1.4e-79 268.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001316264.1_06924001_1 - 4.9e-15 55.4 0.1 1e-14 54.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001316264.1_06924001_1 - 5.6e-09 35.9 0.0 0.00022 20.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 001316264.1_06924001_1 - 2.2e-06 27.0 0.0 0.0017 17.5 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001316264.1_06924001_1 - 1.6e-05 25.3 0.0 0.065 13.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001316264.1_06924001_1 - 0.00022 19.9 0.1 0.027 13.0 0.5 2.3 2 0 0 2 2 2 1 HI0933-like protein MCRA PF06100.9 001316264.1_06924001_1 - 0.00059 18.6 0.0 0.27 9.8 0.0 2.1 2 0 0 2 2 2 2 MCRA family FAD_binding_2 PF00890.22 001316264.1_06924001_1 - 0.0012 17.9 0.7 0.0018 17.3 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.17 001316264.1_06924001_1 - 0.0013 17.9 0.1 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.5 001316264.1_06924001_1 - 0.0014 18.0 0.1 0.0021 17.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.15 001316264.1_06924001_1 - 0.0055 15.9 0.1 0.0099 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.12 001316264.1_06924001_1 - 0.0078 15.0 0.3 3 6.4 0.1 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.10 001316264.1_06924001_1 - 0.015 14.2 0.0 0.092 11.6 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.12 001316264.1_06924001_1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RNase_H2-Ydr279 PF09468.8 001316264.1_06924001_1 - 0.042 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GIDA PF01134.20 001316264.1_06924001_1 - 0.49 9.3 1.2 0.89 8.4 0.7 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A ubiquitin PF00240.21 001316145.1_06923001_3 - 2.6e-15 55.7 0.1 5e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.9 001316145.1_06923001_3 - 1.7e-14 53.2 4.6 3.2e-14 52.3 4.6 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.29 001316145.1_06923001_3 - 8.3e-09 35.1 3.8 0.00027 20.6 0.4 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.6 001316145.1_06923001_3 - 5.9e-05 22.7 0.1 0.00013 21.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001316145.1_06923001_3 - 0.0054 17.0 0.0 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.7 001316145.1_06923001_3 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain BURP PF03181.13 001315969.1_06923001_2 - 1.4e-67 227.3 0.0 1.7e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 BURP domain GREB1 PF15782.3 001315969.1_06923001_2 - 0.063 10.3 0.0 0.079 9.9 0.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3675 PF12428.6 001315648.1_06922001_1 - 8.6e-40 135.9 0.0 2.1e-39 134.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3675) RINGv PF12906.5 001315648.1_06922001_1 - 2.3e-12 46.7 13.6 3.7e-12 46.0 13.6 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.4 001315648.1_06922001_1 - 0.016 15.3 10.0 0.1 12.7 10.7 2.0 1 1 1 2 2 2 0 Ring finger domain DUF2024 PF09630.8 001315648.1_06922001_1 - 0.75 9.6 3.1 0.38 10.5 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) HCO3_cotransp PF00955.19 001316231.1_06925001_1 - 3.7e-84 283.3 4.1 3.9e-36 124.9 2.1 3.1 2 1 1 3 3 3 3 HCO3- transporter family Pkinase PF00069.23 001315663.1_06924001_1 - 3.5e-67 226.4 0.0 4.8e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315663.1_06924001_1 - 1.4e-31 109.6 0.0 2.5e-31 108.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001315663.1_06924001_1 - 1.7e-07 30.6 0.5 3.1e-07 29.8 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001315663.1_06924001_1 - 0.0023 17.2 0.0 0.016 14.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Sulfate_transp PF00916.18 001315588.1_06925001_1 - 6.4e-136 452.9 17.5 8.6e-136 452.5 17.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001315588.1_06925001_1 - 8.3e-27 93.0 0.0 2.6e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.4 001315588.1_06925001_1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 STAS domain Thiolase_N PF00108.21 001315753.1_06923001_1 - 1.1e-78 264.1 0.3 1.4e-78 263.7 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.16 001315753.1_06923001_1 - 3.1e-48 162.4 0.9 5.4e-48 161.6 0.9 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.8 001315753.1_06923001_1 - 0.0024 17.8 0.2 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF834 PF05754.12 001315753.1_06923001_1 - 0.18 11.9 2.0 0.39 10.8 0.1 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF834) Myb_CC_LHEQLE PF14379.4 001315671.1_06923001_1 - 2.9e-24 84.4 13.3 2.9e-24 84.4 13.3 1.7 2 0 0 2 2 2 1 MYB-CC type transfactor, LHEQLE motif Myb_DNA-binding PF00249.29 001315671.1_06923001_1 - 4.8e-10 39.3 0.0 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SKA1 PF07160.10 001315671.1_06923001_1 - 0.73 9.5 12.9 0.056 13.2 7.0 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Pyridoxal_deC PF00282.17 001316081.1_06924001_3 - 2.5e-24 85.6 0.0 5.2e-24 84.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pkinase PF00069.23 001316099.1_06923001_1 - 3.8e-69 232.9 0.0 5.2e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316099.1_06923001_1 - 1.2e-35 123.0 0.0 2.1e-35 122.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase NAF PF03822.12 001316099.1_06923001_1 - 1.3e-17 63.6 0.3 2.5e-17 62.7 0.3 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001316099.1_06923001_1 - 2e-07 30.5 0.0 3.8e-06 26.3 0.0 2.4 1 1 0 2 2 2 1 Kinase-like KA1 PF02149.17 001316099.1_06923001_1 - 9.4e-06 25.2 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 FliX PF10768.7 001316099.1_06923001_1 - 0.03 14.7 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Class II flagellar assembly regulator Kdo PF06293.12 001316099.1_06923001_1 - 0.047 12.9 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001316099.1_06923001_1 - 0.061 13.1 0.0 1 9.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.30 001315859.1_06925001_1 - 9.5e-22 76.8 8.9 0.00053 20.6 0.0 7.8 8 0 0 8 8 7 4 WD domain, G-beta repeat zf-C3HC4_2 PF13923.4 001315859.1_06925001_1 - 4e-11 42.4 14.4 9.2e-11 41.3 14.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001315859.1_06925001_1 - 2.1e-08 33.8 14.9 5e-08 32.6 14.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001315859.1_06925001_1 - 4.7e-08 32.6 11.7 1.3e-07 31.2 11.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WD40_like PF17005.3 001315859.1_06925001_1 - 1.8e-07 30.7 0.1 1.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain zf-RING_2 PF13639.4 001315859.1_06925001_1 - 1.6e-06 28.1 13.3 5.5e-06 26.4 13.3 2.0 1 0 0 1 1 1 1 Ring finger domain ANAPC4_WD40 PF12894.5 001315859.1_06925001_1 - 6.9e-06 26.1 0.4 7 6.9 0.0 4.6 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.4 001315859.1_06925001_1 - 0.00011 21.9 13.2 0.00011 21.9 13.2 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001315859.1_06925001_1 - 0.00044 20.1 13.1 0.00044 20.1 13.1 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001315859.1_06925001_1 - 0.0017 18.3 12.5 0.0017 18.3 12.5 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING U-box PF04564.13 001315859.1_06925001_1 - 0.0023 17.9 0.0 0.0074 16.3 0.0 1.8 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.4 001315859.1_06925001_1 - 0.0038 16.9 11.9 0.011 15.4 11.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 eIF2A PF08662.9 001315859.1_06925001_1 - 0.027 14.2 0.1 2.7 7.7 0.0 3.0 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF1664 PF07889.10 001315859.1_06925001_1 - 0.055 13.3 1.2 0.14 12.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-RING_10 PF16685.3 001315859.1_06925001_1 - 0.09 12.8 7.8 0.29 11.2 7.8 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.4 001315859.1_06925001_1 - 0.13 12.0 3.7 0.34 10.7 3.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_p24 PF05073.10 001315859.1_06925001_1 - 0.19 11.3 2.3 0.87 9.2 0.2 2.6 3 0 0 3 3 3 0 Baculovirus P24 capsid protein zf-rbx1 PF12678.5 001315859.1_06925001_1 - 0.42 10.8 16.0 0.24 11.6 12.0 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-Nse PF11789.6 001315859.1_06925001_1 - 2.2 8.0 11.0 1.9 8.3 7.3 2.6 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.5 001315859.1_06925001_1 - 6 6.9 9.5 7.4 6.6 5.5 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cpn60_TCP1 PF00118.22 001316161.1_06924001_3 - 1.3e-90 304.3 13.7 2e-90 303.7 13.7 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Heme_oxygenase PF01126.18 001316158.1_06923001_2 - 1.9e-08 34.2 0.1 2.7e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Heme oxygenase Pkinase_Tyr PF07714.15 001316170.1_06924001_1 - 3.7e-73 245.9 0.1 5.3e-73 245.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001316170.1_06924001_1 - 9.7e-62 208.6 0.1 1.4e-61 208.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain ACT PF01842.23 001316170.1_06924001_1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain APH PF01636.21 001316170.1_06924001_1 - 0.0033 17.2 3.0 0.28 11.0 0.1 2.9 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.4 001316170.1_06924001_1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Gln-synt_C PF00120.22 001316139.1_06924001_1 - 2.8e-16 59.3 0.0 5.2e-15 55.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001316139.1_06924001_1 - 1.6e-10 40.5 0.0 2.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MatE PF01554.16 151622.1_53729120_2 - 1e-19 70.7 11.5 1.8e-19 69.8 11.5 1.4 1 0 0 1 1 1 1 MatE AP2 PF00847.18 001310053.1_48023001_3 - 6.8e-14 51.7 0.6 1.4e-13 50.7 0.6 1.6 1 0 0 1 1 1 1 AP2 domain Lipoprotein_17 PF04200.10 001310053.1_48023001_3 - 0.041 14.1 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein associated domain zf-C3HC4_3 PF13920.4 001324731.1_09326001_1 - 7.2e-11 41.6 10.2 7.2e-11 41.6 10.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001324731.1_09326001_1 - 0.0016 18.1 12.1 0.0016 18.1 12.1 2.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-UDP PF14569.4 001324731.1_09326001_1 - 0.19 11.7 5.4 0.8 9.7 5.4 2.1 1 0 0 1 1 1 0 Zinc-binding RING-finger CorA PF01544.16 001324731.1_09326001_1 - 1 8.5 13.6 0.031 13.5 5.7 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Acyl-CoA_dh_2 PF08028.9 001324731.1_09326001_1 - 2.4 8.3 8.1 12 6.0 6.1 2.4 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain zf-RING_4 PF14570.4 001324731.1_09326001_1 - 5.9 6.6 8.2 6.1 6.5 5.9 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PEPcase PF00311.15 001280813.1_48026001_1 - 0 1021.3 0.0 0 1021.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.4 001280813.1_48026001_1 - 9.5e-06 24.2 0.0 1.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Oxidored_FMN PF00724.18 001310052.1_48023001_1 - 4.5e-91 305.5 0.0 5.4e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3700 PF12481.6 001280844.1_48023001_1 - 1.7e-103 344.8 0.0 2.1e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 Aluminium induced protein GATase_7 PF13537.4 001280844.1_48023001_1 - 4.5e-09 36.1 0.0 6.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001280844.1_48023001_1 - 2.5e-05 24.4 0.0 3.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain Tic110 PF16940.3 001280844.1_48023001_1 - 0.095 11.0 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter bZIP_1 PF00170.19 001310051.1_48023001_1 - 1e-11 44.6 14.2 1.9e-11 43.7 14.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001310051.1_48023001_1 - 4e-10 39.5 14.7 8.2e-10 38.5 14.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001310051.1_48023001_1 - 0.0049 17.2 7.9 0.0049 17.2 7.9 2.4 2 1 0 2 2 2 1 bZIP Maf transcription factor LEA_2 PF03168.11 001310054.1_48022001_1 - 5.4e-18 65.2 0.0 8.5e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF4981 PF16353.3 001310054.1_48022001_1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Ribonuclease_T2 PF00445.16 001287232.1_48022001_1 - 1.7e-34 119.5 0.7 2.2e-34 119.1 0.7 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family ADH_zinc_N_2 PF13602.4 001280802.1_48023001_1 - 2.6e-19 70.4 0.3 5.4e-19 69.4 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.24 001280802.1_48023001_1 - 2.3e-12 46.8 1.2 3.7e-12 46.1 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001280802.1_48023001_1 - 6.7e-07 29.0 0.0 1.9e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.3 001280802.1_48023001_1 - 0.079 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.19 001280802.1_48023001_1 - 0.099 11.8 3.8 0.17 11.0 3.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_5 PF07994.10 001280847.1_48024001_1 - 1.2e-144 481.5 0.0 1.3e-144 481.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.15 001280847.1_48024001_1 - 2.6e-48 162.6 0.1 2.6e-48 162.6 0.1 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Tryp_alpha_amyl PF00234.20 001287536.1_48022001_1 - 9.5e-09 35.4 1.9 1.8e-08 34.5 1.9 1.4 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family LTP_2 PF14368.4 001287536.1_48022001_1 - 2.6e-06 27.3 3.7 5.6e-06 26.3 3.7 1.5 1 0 0 1 1 1 1 Probable lipid transfer TcdA_TcdB_pore PF12920.5 001287536.1_48022001_1 - 0.52 8.3 1.8 0.68 8.0 1.8 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain CHORD PF04968.10 001280832.1_48022001_1 - 9.7e-49 163.8 18.5 1.2e-24 86.7 9.6 2.3 2 0 0 2 2 2 2 CHORD PLD_C PF12357.6 001280835.1_48026001_2 - 7.5e-30 102.5 0.0 1.3e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.20 001280835.1_48026001_2 - 3.4e-21 74.4 0.6 9.6e-11 41.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif C2 PF00168.28 001280835.1_48026001_2 - 1.1e-14 54.4 0.0 2.7e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain PLDc_2 PF13091.4 001280835.1_48026001_2 - 4.1e-10 39.5 0.0 1.5e-06 28.0 0.1 3.4 2 2 0 2 2 2 2 PLD-like domain F-box PF00646.31 001280811.1_48022001_1 - 0.00058 19.5 0.5 0.0011 18.6 0.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001280811.1_48022001_1 - 0.0086 15.8 0.2 0.014 15.1 0.2 1.3 1 0 0 1 1 1 1 F-box-like ACC_central PF08326.10 001280805.1_48029001_3 - 1.4e-174 582.1 3.7 1.8e-174 581.7 3.7 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.20 001280805.1_48029001_3 - 6.8e-172 572.4 0.0 1e-171 571.9 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.15 001280805.1_48029001_3 - 4.1e-47 160.3 0.0 7.7e-47 159.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.20 001280805.1_48029001_3 - 1.9e-31 108.7 0.0 5.5e-31 107.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.17 001280805.1_48029001_3 - 2.8e-23 81.9 0.0 1.2e-22 79.9 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.20 001280805.1_48029001_3 - 8.5e-12 44.6 0.0 2.2e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.12 001280805.1_48029001_3 - 4.4e-11 42.9 0.3 1.5e-08 34.8 0.0 3.2 4 0 0 4 4 4 1 ATP-grasp domain ATP-grasp PF02222.20 001280805.1_48029001_3 - 1.6e-06 27.7 0.1 4.3e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.11 001280805.1_48029001_3 - 6e-05 22.5 0.0 0.00024 20.6 0.0 2.0 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Phosphatase PF15698.3 001280805.1_48029001_3 - 0.076 12.0 0.1 0.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphatase Glyco_transf_5 PF08323.9 001280821.1_48025001_1 - 7.2e-73 245.1 0.0 1.4e-72 244.2 0.0 1.5 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 001280821.1_48025001_1 - 7.2e-18 64.6 0.0 1.2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001280821.1_48025001_1 - 4.3e-15 56.2 0.3 7.9e-15 55.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001280821.1_48025001_1 - 0.00051 19.9 0.0 0.82 9.5 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase Family 4 PEPcase PF00311.15 001280829.1_48027001_1 - 0 1022.1 0.0 0 1021.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.4 001280829.1_48027001_1 - 0.0012 17.4 0.0 0.0024 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase NTP_transferase PF00483.21 001288466.1_48624001_1 - 9e-71 238.2 0.0 1.2e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001288466.1_48624001_1 - 0.0016 18.7 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001288466.1_48624001_1 - 0.0055 16.3 7.2 0.021 14.4 1.1 3.2 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.10 001288466.1_48624001_1 - 0.14 11.0 0.4 15 4.3 0.1 2.8 2 1 1 3 3 3 0 L-fucokinase G6PD_C PF02781.14 001288109.1_48625001_2 - 1.2e-110 369.2 0.0 1.6e-110 368.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.20 001288109.1_48625001_2 - 4.6e-57 193.4 0.0 7.1e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Cytochrom_C1 PF02167.13 001288448.1_48623001_2 - 5.8e-95 317.0 0.0 7.1e-95 316.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.4 001288448.1_48623001_2 - 0.0013 18.8 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.19 001288448.1_48623001_2 - 0.02 15.9 0.0 0.05 14.6 0.0 1.8 1 0 0 1 1 1 0 Cytochrome c Gp_dh_N PF00044.22 001288448.1_48623001_2 - 0.12 12.5 0.3 0.3 11.3 0.2 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pectinesterase PF01095.17 001288930.1_12724001_2 - 9.1e-149 494.0 3.8 1.3e-148 493.4 3.8 1.2 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.13 001288930.1_12724001_2 - 9.9e-30 103.6 4.9 2e-29 102.6 4.9 1.6 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Syntaxin-6_N PF09177.9 001288930.1_12724001_2 - 0.043 14.2 0.5 0.098 13.1 0.5 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF4134 PF13572.4 001288930.1_12724001_2 - 0.071 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) CorA PF01544.16 001288930.1_12724001_2 - 0.12 11.5 2.5 0.13 11.4 0.7 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PAD_M PF08527.8 001288930.1_12724001_2 - 0.41 10.2 3.3 0.51 9.9 0.0 2.6 3 0 0 3 3 3 0 Protein-arginine deiminase (PAD) middle domain UCR_14kD PF02271.14 001287958.1_48622001_1 - 1e-26 92.7 1.9 1.3e-26 92.3 1.9 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Chalcone PF02431.13 001288937.1_12722001_3 - 2.9e-101 336.9 0.5 3.4e-101 336.7 0.5 1.0 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Chalcone_2 PF16035.3 001288937.1_12722001_3 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.5 2 0 0 2 2 2 1 Chalcone isomerase like Epimerase PF01370.19 001293939.1_29823001_1 - 2.2e-27 96.0 0.0 3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001293939.1_29823001_1 - 1.5e-20 73.2 0.0 2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.3 001293939.1_29823001_1 - 2.2e-17 63.3 0.0 5.1e-17 62.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 001293939.1_29823001_1 - 5.5e-15 55.6 0.0 8.2e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001293939.1_29823001_1 - 4.9e-14 52.0 0.0 3e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.11 001293939.1_29823001_1 - 6.2e-12 45.4 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.8 001293939.1_29823001_1 - 7.4e-07 29.1 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.23 001293939.1_29823001_1 - 2.6e-05 23.6 0.0 6.3e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.13 001293939.1_29823001_1 - 3.3e-05 23.1 0.0 5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AdoHcyase PF05221.15 001302609.1_35125001_2 - 1.3e-145 484.0 0.0 1.5e-145 483.8 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.19 001302609.1_35125001_2 - 8.7e-83 276.1 2.1 1.3e-82 275.5 2.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.17 001302609.1_35125001_2 - 1.6e-08 34.0 0.2 3e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.10 001302609.1_35125001_2 - 0.00082 18.8 0.3 0.0015 18.0 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.4 001302609.1_35125001_2 - 0.0014 18.9 0.6 0.0039 17.5 0.6 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.16 001302609.1_35125001_2 - 0.0052 16.9 0.4 0.015 15.4 0.4 1.8 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.19 001302609.1_35125001_2 - 0.11 12.0 0.5 0.2 11.2 0.4 1.4 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.18 001302609.1_35125001_2 - 0.12 12.3 0.6 0.27 11.2 0.6 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Spermine_synth PF01564.15 001302585.1_35123001_1 - 1.2e-98 328.9 0.0 1.5e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_25 PF13649.4 001302585.1_35123001_1 - 4.2e-05 24.0 0.0 8.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.9 001302585.1_35123001_1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.12 001302585.1_35123001_1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Kelch_1 PF01344.23 001302585.1_35123001_1 - 0.027 13.9 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Methyltransf_24 PF13578.4 001302585.1_35123001_1 - 0.079 13.9 0.0 0.15 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.15 001302585.1_35123001_1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Terpene_synth_C PF03936.14 001297453.1_14824001_1 - 5.6e-105 350.4 2.5 5.6e-105 350.4 2.5 1.9 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001297453.1_14824001_1 - 3.6e-55 186.5 4.9 7.5e-55 185.4 4.9 1.6 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain ANTAR PF03861.12 001297453.1_14824001_1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 ANTAR domain Profilin PF00235.17 001297545.1_14822001_1 - 2e-42 144.3 0.0 2.4e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Profilin RNA_pol PF00940.17 001302573.1_35127001_1 - 1.8e-160 534.1 0.0 3.2e-160 533.3 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.4 001302573.1_35127001_1 - 8e-88 294.9 1.2 1.1e-87 294.4 0.3 1.7 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Lambda_CIII PF02061.14 001302573.1_35127001_1 - 0.049 13.6 0.0 0.48 10.4 0.0 2.6 2 0 0 2 2 2 0 Lambda Phage CIII Emaravirus_P4 PF16505.3 001311181.1_35122001_1 - 0.11 11.3 1.2 0.15 10.9 0.5 1.4 1 1 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily CSD PF00313.20 001311181.1_35122001_3 - 6.7e-27 93.0 0.3 9.8e-27 92.5 0.3 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.21 001311181.1_35122001_3 - 3.4e-15 55.2 14.7 1.7e-07 30.9 2.7 2.4 2 0 0 2 2 2 2 Zinc knuckle OB_RNB PF08206.9 001311181.1_35122001_3 - 6.9e-05 22.3 1.1 0.00013 21.4 0.6 1.8 1 1 1 2 2 2 1 Ribonuclease B OB domain zf-CCHC_5 PF14787.4 001311181.1_35122001_3 - 0.00059 19.3 7.2 0.16 11.6 1.0 2.3 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.4 001311181.1_35122001_3 - 0.015 15.1 7.8 0.38 10.6 1.5 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.4 001311181.1_35122001_3 - 3.6 7.4 10.0 1.2 8.9 1.1 2.3 2 0 0 2 2 2 0 Zinc knuckle PsaD PF02531.14 001312650.1_35123001_2 - 4.2e-68 227.0 0.1 5.8e-68 226.5 0.1 1.2 1 0 0 1 1 1 1 PsaD FAP PF07174.9 001312650.1_35123001_2 - 0.14 11.5 4.8 0.2 10.9 4.8 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Terpene_synth_C PF03936.14 001323759.1_46324001_1 - 1e-88 297.0 0.4 1.5e-88 296.5 0.4 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001323759.1_46324001_1 - 5.9e-53 179.3 1.4 1.5e-52 177.9 1.4 1.7 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain DAHP_synth_2 PF01474.14 001325203.1_35224001_1 - 1.3e-195 649.9 0.0 1.6e-195 649.6 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Sod_Fe_C PF02777.16 001324998.1_09322001_2 - 9.4e-36 121.9 0.8 1.5e-35 121.2 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.20 001324998.1_09322001_2 - 1.4e-32 111.8 1.2 2.4e-32 111.1 1.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sugar_tr PF00083.22 001323706.1_46324001_3 - 6.2e-118 394.4 22.1 7.3e-118 394.1 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001323706.1_46324001_3 - 5.2e-23 81.4 29.2 5.2e-23 81.4 29.2 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.11 001323706.1_46324001_3 - 4.9e-05 21.8 0.9 4.9e-05 21.8 0.9 2.5 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) RB_A PF01858.15 001325239.1_35227001_2 - 5.8e-64 215.5 0.3 9.7e-64 214.7 0.3 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain DUF3452 PF11934.6 001325239.1_35227001_2 - 6.2e-36 122.9 2.1 1.5e-35 121.6 0.1 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3452) RB_B PF01857.18 001325239.1_35227001_2 - 1.7e-23 83.0 2.7 7.5e-20 71.2 0.4 2.6 1 1 1 2 2 2 2 Retinoblastoma-associated protein B domain Rb_C PF08934.8 001325239.1_35227001_2 - 0.0097 15.6 0.1 0.0097 15.6 0.1 2.5 3 0 0 3 3 3 1 Rb C-terminal domain AAA_10 PF12846.5 001325239.1_35227001_2 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Amino_oxidase PF01593.22 001324813.1_09324001_1 - 2.8e-79 267.4 0.0 5.4e-79 266.4 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001324813.1_09324001_1 - 3.7e-14 52.6 0.5 2.9e-13 49.7 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.12 001324813.1_09324001_1 - 8.3e-08 31.7 0.0 0.0061 15.7 0.3 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001324813.1_09324001_1 - 2.1e-07 30.7 0.0 0.0032 17.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.25 001324813.1_09324001_1 - 5e-05 23.7 0.1 0.21 12.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.9 001324813.1_09324001_1 - 0.00062 18.5 0.0 0.77 8.3 0.0 2.1 2 0 0 2 2 2 2 MCRA family FAD_oxidored PF12831.5 001324813.1_09324001_1 - 0.00093 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.12 001324813.1_09324001_1 - 0.0027 16.3 0.2 1.7 7.1 0.7 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.22 001324813.1_09324001_1 - 0.0048 15.9 0.8 0.0072 15.3 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.15 001324813.1_09324001_1 - 0.0065 15.6 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family UDPG_MGDP_dh_N PF03721.12 001324813.1_09324001_1 - 0.044 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.17 001324813.1_09324001_1 - 0.051 12.7 0.2 0.091 11.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.12 001324813.1_09324001_1 - 0.074 11.8 0.4 2 7.1 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase RIP PF00161.17 001323701.1_46324001_1 - 1.1e-50 171.9 0.0 1.7e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Ribosome inactivating protein Ricin_B_lectin PF00652.20 001323701.1_46324001_1 - 8.6e-46 155.2 1.5 6.4e-22 78.0 0.3 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.4 001323701.1_46324001_1 - 7.7e-16 58.5 6.0 5e-05 23.8 0.1 4.7 2 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like PALP PF00291.23 001288049.2_48623001_3 - 5e-68 229.5 0.3 5.8e-68 229.3 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme URO-D PF01208.15 001325911.1_35223001_3 - 4.4e-115 384.4 0.0 5.1e-115 384.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) ketoacyl-synt PF00109.24 001303467.1_08325001_2 - 7.2e-60 202.5 0.6 1.3e-59 201.7 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.20 001303467.1_08325001_2 - 1.6e-34 118.3 0.1 2.6e-34 117.6 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.21 001303467.1_08325001_2 - 0.0079 15.5 0.3 0.016 14.4 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Melibiase_2 PF16499.3 001280601.1_14924001_1 - 7.1e-96 321.1 3.4 9.6e-96 320.6 3.4 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.16 001280601.1_14924001_1 - 5.9e-07 28.6 0.0 2e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Melibiase EzrA PF06160.10 152388.1_53726120_1 - 0.041 11.9 2.2 0.053 11.6 2.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.6 152388.1_53726120_1 - 0.061 13.4 4.9 0.11 12.5 4.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.20 152388.1_53726120_1 - 0.38 10.9 1.4 11 6.2 1.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.13 152388.1_53726120_1 - 0.85 9.3 2.9 1.4 8.6 2.9 1.2 1 0 0 1 1 1 0 Mnd1 family Inositol_P PF00459.23 001246914.1_48423001_1 - 3.5e-76 256.2 0.0 4.4e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family ubiquitin PF00240.21 001288394.1_48622001_2 - 5.9e-34 115.5 0.4 9.6e-34 114.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.17 001288394.1_48622001_2 - 1.7e-27 95.2 2.4 3.4e-27 94.2 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.6 001288394.1_48622001_2 - 6.6e-16 57.8 0.6 6.6e-16 57.8 0.6 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001288394.1_48622001_2 - 6e-05 23.3 0.2 0.00035 20.8 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.4 001288394.1_48622001_2 - 0.00074 19.5 0.4 0.0015 18.5 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001288394.1_48622001_2 - 0.014 15.8 0.5 0.022 15.2 0.5 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SNAP PF14938.4 001288116.1_48623001_2 - 5.8e-107 357.2 9.1 6.6e-107 357.0 9.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.4 001288116.1_48623001_2 - 7.3e-07 29.3 8.6 0.0017 18.5 0.7 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.15 001288116.1_48623001_2 - 0.00046 20.0 18.7 4.3 7.6 1.3 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat NSF PF02071.18 001288116.1_48623001_2 - 0.0011 19.1 20.6 4.6 8.3 0.0 7.5 7 1 1 8 8 7 1 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.4 001288116.1_48623001_2 - 0.0019 18.0 6.9 6.8 6.8 0.4 5.4 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.4 001288116.1_48623001_2 - 0.0047 17.3 6.2 48 4.8 0.2 5.7 4 1 3 7 7 6 0 Tetratricopeptide repeat Gin PF10764.7 001288116.1_48623001_2 - 0.022 14.6 0.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin TPR_8 PF13181.4 001288116.1_48623001_2 - 0.094 12.9 16.6 4.5 7.6 0.4 5.8 4 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.4 001288116.1_48623001_2 - 0.12 13.1 7.5 12 6.9 0.3 5.2 4 2 3 7 7 7 0 Tetratricopeptide repeat DHR-2 PF06920.11 001288116.1_48623001_2 - 0.12 10.8 3.4 0.11 11.0 1.0 2.0 2 1 0 2 2 2 0 Dock homology region 2 TPR_19 PF14559.4 001288116.1_48623001_2 - 0.28 11.6 9.6 7.2 7.1 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.26 001288116.1_48623001_2 - 3.6 7.4 25.7 3.1 7.7 1.7 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat Cupin_1 PF00190.20 001304407.1_47924001_3 - 2.4e-58 195.9 3.0 1.5e-27 95.9 0.3 3.1 2 1 1 3 3 3 2 Cupin Cupin_2 PF07883.9 001304407.1_47924001_3 - 2.9e-09 36.4 0.1 2.2e-05 24.0 0.0 3.4 3 0 0 3 3 3 2 Cupin domain Cupin_6 PF12852.5 001304407.1_47924001_3 - 0.00093 18.8 0.0 0.63 9.6 0.0 2.3 2 0 0 2 2 2 2 Cupin TRAF_BIRC3_bd PF16673.3 001304407.1_47924001_3 - 0.042 13.5 0.6 0.14 11.8 0.6 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Cupin_3 PF05899.10 001304407.1_47924001_3 - 0.1 12.1 0.0 8.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Sucrose_synth PF00862.17 001317152.1_52926001_2 - 1.1e-283 941.5 0.0 1.4e-283 941.1 0.0 1.2 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001317152.1_52926001_2 - 1.7e-30 105.7 0.0 3.1e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001317152.1_52926001_2 - 1.7e-09 38.1 0.0 4e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001317152.1_52926001_2 - 1.1e-05 25.6 0.0 2.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.25 001317152.1_52926001_2 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain GTP_EFTU PF00009.25 001326165.1_35224001_1 - 1.2e-53 181.5 0.0 2.2e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001326165.1_35224001_1 - 2.8e-38 130.5 0.0 6e-38 129.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001326165.1_35224001_1 - 3.6e-15 56.0 0.3 9.9e-15 54.6 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001326165.1_35224001_1 - 0.0014 18.5 0.2 0.0062 16.5 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001326165.1_35224001_1 - 0.0068 16.2 0.8 0.019 14.8 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 SRPRB PF09439.8 001326165.1_35224001_1 - 0.027 13.8 0.1 0.31 10.3 0.1 2.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FlpD PF02662.14 001326165.1_35224001_1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Ribosomal_S2 PF00318.18 001315694.1_06923001_1 - 8.9e-26 90.3 0.1 5.2e-12 45.3 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.3 001315694.1_06923001_1 - 0.08 14.2 13.0 0.16 13.3 13.0 1.5 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus Glyco_hydro_32N PF00251.18 001317324.1_52925001_2 - 4.5e-110 367.9 3.5 5.6e-110 367.5 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF3357 PF11837.6 001317324.1_52925001_2 - 1.7e-18 66.9 0.0 3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Glyco_hydro_32C PF08244.10 001317324.1_52925001_2 - 1.8e-15 57.3 0.0 3.5e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal GST_N_3 PF13417.4 001323853.2_53923001_2 - 4.3e-18 65.3 0.0 7.7e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001323853.2_53923001_2 - 4.9e-18 65.1 0.1 8e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001323853.2_53923001_2 - 7.3e-13 48.5 0.0 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.2 001323853.2_53923001_2 - 0.014 16.0 0.0 0.11 13.2 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Ribosomal_S9 PF00380.17 152383.1_53728120_1 - 0.0016 18.8 0.1 0.004 17.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Atrophin-1 PF03154.13 152383.1_53728120_1 - 0.016 13.4 9.4 0.023 12.9 9.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 152383.1_53728120_1 - 0.24 11.3 8.9 0.43 10.4 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FAM27 PF15832.3 152383.1_53728120_1 - 0.57 10.6 7.0 1.1 9.7 7.0 1.4 1 0 0 1 1 1 0 FAM27 D and E protein family Rrn6 PF10214.7 152383.1_53728120_1 - 1.7 6.9 8.8 2.4 6.3 8.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Atrophin-1 PF03154.13 152383.1_53728120_2 - 0.00022 19.6 5.8 0.00022 19.6 5.8 1.6 2 0 0 2 2 2 1 Atrophin-1 family DUF3915 PF13054.4 152383.1_53728120_2 - 0.00099 18.9 5.8 0.0021 17.9 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) DUF4283 PF14111.4 152383.1_53728120_3 - 1.8e-06 27.4 0.1 3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4283) DUF3915 PF13054.4 152383.1_53728120_3 - 0.0018 18.1 1.6 0.0039 17.0 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 152383.1_53728120_3 - 0.004 15.4 5.8 0.0064 14.7 5.8 1.2 1 0 0 1 1 1 1 Atrophin-1 family FAM27 PF15832.3 152383.1_53728120_3 - 2.3 8.7 6.0 6.3 7.3 6.0 1.6 1 0 0 1 1 1 0 FAM27 D and E protein family NAD_binding_1 PF00175.19 152520.1_53722120_2 - 6.1e-19 68.5 0.1 8.7e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3854 PF12965.5 152520.1_53722120_2 - 0.077 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Profilin PF00235.17 001247044.3_48422001_2 - 8.6e-44 148.7 0.0 1.1e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Profilin DUF1201 PF06716.9 001247044.3_48422001_2 - 0.0085 15.9 5.9 0.019 14.9 5.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1201) Lipoxygenase PF00305.17 001288240.1_48626001_1 - 0 1061.4 0.0 0 1061.2 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001288240.1_48626001_1 - 2.1e-20 73.3 0.0 4.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Lipoxygenase PF00305.17 001248454.2_24126001_2 - 0 1050.4 0.0 0 1050.2 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001248454.2_24126001_2 - 1.6e-16 60.8 0.0 4.3e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain Myb_DNA-binding PF00249.29 001281073.1_53022001_1 - 1.2e-31 108.5 3.6 1.3e-15 57.1 1.9 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001281073.1_53022001_1 - 8.2e-22 77.1 0.1 7e-13 48.5 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Acyltransf_C PF16076.3 001281073.1_53022001_1 - 0.029 14.4 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase C-terminus SANT_DAMP1_like PF16282.3 001281073.1_53022001_1 - 0.072 13.2 0.7 2.7 8.1 0.0 2.6 2 1 0 3 3 3 0 SANT/Myb-like domain of DAMP1 zf-B_box PF00643.22 001346834.1_53724001_1 - 3.5e-12 46.1 10.5 6.3e-07 29.3 0.8 2.3 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.3 001346834.1_53724001_1 - 0.006 16.7 10.2 0.018 15.1 0.4 2.4 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF2318 PF10080.7 001346834.1_53724001_1 - 0.019 14.9 0.7 0.019 14.9 0.7 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) YTH PF04146.13 146398.1_53726120_1 - 2e-32 111.3 0.5 3e-32 110.7 0.5 1.2 1 0 0 1 1 1 1 YT521-B-like domain zf-UBP PF02148.17 146398.1_53726120_2 - 0.0014 18.8 0.1 0.0038 17.4 0.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein PDT PF00800.16 146398.1_53726120_3 - 2e-18 66.7 0.0 3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase DUF1230 PF06799.9 146319.1_53722120_1 - 3.9e-29 101.5 0.0 1.2e-28 99.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1230) Glyco_transf_43 PF03360.14 147023.1_53726120_1 - 3.3e-15 56.3 0.0 4.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 PLDc_2 PF13091.4 147023.1_53726120_1 - 5.7e-08 32.6 0.3 9.2e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.20 147023.1_53726120_1 - 1.7e-07 31.0 0.2 3.4e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc PF00614.20 147023.1_53726120_3 - 8.8e-08 31.9 0.2 1.5e-07 31.2 0.2 1.4 1 0 0 1 1 1 1 Phospholipase D Active site motif GUB_WAK_bind PF13947.4 001347659.1_09323001_2 - 1.8e-08 35.0 1.0 4.3e-08 33.8 1.0 1.7 1 0 0 1 1 1 1 Wall-associated receptor kinase galacturonan-binding WAK_assoc PF14380.4 001347659.1_09323001_2 - 0.0013 19.3 0.3 0.0028 18.2 0.3 1.6 1 0 0 1 1 1 1 Wall-associated receptor kinase C-terminal LEA_1 PF03760.13 001279130.1_12221001_1 - 4.4e-21 75.2 20.4 7.2e-21 74.5 20.4 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant (LEA) group 1 PV-1 PF06637.9 001279130.1_12221001_1 - 0.066 11.9 3.8 0.069 11.8 3.8 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Phage_holin_7_1 PF16081.3 001279130.1_12221001_1 - 0.15 12.1 1.7 0.2 11.7 1.7 1.2 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Tho2 PF11262.6 001279130.1_12221001_1 - 0.51 9.3 5.1 0.6 9.1 5.1 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TRAP-gamma PF07074.10 001279130.1_12221001_1 - 4.7 6.6 5.1 6.1 6.2 5.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Pollen_allerg_1 PF01357.19 001279041.1_12223001_3 - 1.8e-30 104.7 0.8 3e-30 104.0 0.8 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001279041.1_12223001_3 - 9.8e-23 80.1 0.0 2.4e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase Proteasome PF00227.24 001279054.1_12223001_1 - 6.2e-31 107.2 0.3 5.3e-29 100.9 0.1 2.1 1 1 1 2 2 2 2 Proteasome subunit NTP_transferase PF00483.21 001279202.1_12224001_1 - 4.8e-76 255.5 0.0 6.1e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001279202.1_12224001_1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.10 001279202.1_12224001_1 - 0.0094 14.9 0.7 0.83 8.5 0.7 2.9 1 1 0 1 1 1 1 L-fucokinase Hexapep PF00132.22 001279202.1_12224001_1 - 0.02 14.4 8.6 0.03 13.9 2.6 3.2 3 0 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.3 001279202.1_12224001_1 - 2.6 5.9 6.2 3.8 5.4 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Cys_Met_Meta_PP PF01053.18 001279021.1_12224001_1 - 2.6e-139 463.9 0.0 3.1e-139 463.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.19 001279021.1_12224001_1 - 1.9e-08 33.8 0.0 4.4e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001279021.1_12224001_1 - 2.9e-06 26.7 0.0 5.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.17 001279021.1_12224001_1 - 0.0044 15.9 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.9 001279021.1_12224001_1 - 0.16 10.4 0.1 0.4 9.0 0.0 1.6 2 0 0 2 2 2 0 Methionine gamma-lyase SelA PF03841.11 001279021.1_12224001_1 - 0.17 10.7 0.0 1.9 7.3 0.0 2.0 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase Steroid_dh PF02544.14 001278955.1_12223001_3 - 3.5e-27 95.1 2.7 6e-27 94.3 2.7 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.21 001278955.1_12223001_3 - 0.081 12.5 0.0 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin family peroxidase PF00141.21 001279207.1_12223001_1 - 1.1e-60 205.1 0.0 1.4e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Pectinesterase PF01095.17 001278972.1_12225001_1 - 2e-148 492.8 3.5 2.9e-148 492.3 3.5 1.2 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.13 001278972.1_12225001_1 - 8.3e-28 97.4 1.7 8.3e-28 97.4 1.7 2.0 2 0 0 2 2 2 1 Plant invertase/pectin methylesterase inhibitor Band_7 PF01145.23 001279014.1_12223001_1 - 2e-25 89.7 1.2 2.6e-25 89.4 1.2 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ribosomal_S3Ae PF01015.16 001279014.1_12223001_1 - 0.0079 15.7 1.2 0.014 14.9 1.2 1.3 1 0 0 1 1 1 1 Ribosomal S3Ae family Band_7_1 PF13421.4 001279014.1_12223001_1 - 0.014 15.0 0.4 0.047 13.2 0.2 1.8 2 0 0 2 2 2 0 SPFH domain-Band 7 family Psu PF07455.9 001279014.1_12223001_1 - 0.1 12.0 0.8 0.16 11.4 0.8 1.2 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) p450 PF00067.20 001302274.1_12224001_1 - 4.2e-95 319.1 0.0 4.9e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRP9_N PF16958.3 001302274.1_12224001_1 - 0.29 11.0 1.4 13 5.7 0.0 2.8 3 0 0 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus GSHPx PF00255.17 001286528.1_12222001_1 - 4.7e-41 138.6 0.8 5.8e-41 138.3 0.8 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 001286528.1_12222001_1 - 1.3e-08 34.7 0.1 8.8e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.8 001286528.1_12222001_1 - 8.1e-08 31.9 0.0 4.8e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Redoxin SCO1-SenC PF02630.12 001286528.1_12222001_1 - 0.0011 18.7 0.2 0.26 11.0 0.1 2.1 2 0 0 2 2 2 2 SCO1/SenC Atg8 PF02991.14 001279004.1_12222001_2 - 2.2e-50 169.0 0.1 3.2e-50 168.5 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.11 001279004.1_12222001_2 - 6.7e-07 29.5 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 EF-hand_1 PF00036.30 001279096.1_12222001_3 - 2.1e-40 133.1 11.5 8.6e-10 37.3 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001279096.1_12222001_3 - 2e-34 117.8 3.5 1.4e-17 63.8 1.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001279096.1_12222001_3 - 7.6e-30 102.3 9.0 3.1e-14 52.3 0.4 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.4 001279096.1_12222001_3 - 5e-29 97.6 6.5 4.7e-09 35.3 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001279096.1_12222001_3 - 7.8e-25 85.1 8.5 3.6e-06 26.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001279096.1_12222001_3 - 1.5e-15 57.1 0.2 6.2e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001279096.1_12222001_3 - 2.3e-08 33.8 1.3 0.00016 21.4 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001279096.1_12222001_3 - 3e-07 30.6 1.1 0.0046 17.1 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001279096.1_12222001_3 - 6e-05 23.7 0.1 0.0013 19.4 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.11 001279096.1_12222001_3 - 0.00011 22.0 0.1 0.12 12.2 0.0 2.8 3 1 0 3 3 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.8 001279096.1_12222001_3 - 0.00065 19.6 0.7 0.0018 18.2 0.3 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.14 001279096.1_12222001_3 - 0.0017 18.6 0.1 2.6 8.3 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb4 Caleosin PF05042.11 001279096.1_12222001_3 - 0.0077 16.0 0.2 1.3 8.8 0.0 2.8 1 1 2 3 3 3 1 Caleosin related protein DUF3349 PF11829.6 001279096.1_12222001_3 - 0.011 16.4 0.3 4.8 7.9 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) MotA_activ PF09114.8 001279096.1_12222001_3 - 0.023 14.7 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain TerB PF05099.11 001279096.1_12222001_3 - 0.028 14.3 0.3 6.8 6.5 0.1 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB Poly_export PF02563.14 001279096.1_12222001_3 - 0.089 12.9 0.0 2.9 8.0 0.0 2.6 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.4 001279096.1_12222001_3 - 0.089 12.5 0.8 1.9 8.2 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain p450 PF00067.20 001282318.1_12224001_2 - 1.8e-101 340.1 0.0 2.3e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kunitz_legume PF00197.16 001309666.1_12222001_1 - 1.8e-30 106.0 0.0 2.3e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor Bet_v_1 PF00407.17 001309680.1_12222001_3 - 5.3e-44 149.6 2.7 6.3e-44 149.4 2.7 1.0 1 0 0 1 1 1 1 Pathogenesis-related protein Bet v I family Herpes_IE2_3 PF03361.12 001309680.1_12222001_3 - 0.0026 17.5 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Herpes virus intermediate/early protein 2/3 EB_dh PF09459.8 001360200.1_39024001_1 - 1.1e-26 94.2 0.4 1.3e-26 93.9 0.4 1.1 1 0 0 1 1 1 1 Ethylbenzene dehydrogenase RskA PF10099.7 001360200.1_39024001_1 - 0.33 11.1 8.4 1.3 9.2 5.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Fip1 PF05182.11 001360205.1_38127001_1 - 1.8e-19 68.8 1.4 4.4e-19 67.6 1.4 1.7 1 0 0 1 1 1 1 Fip1 motif EB_dh PF09459.8 001360194.1_48024001_3 - 1.2e-25 90.8 1.8 1.5e-25 90.5 1.8 1.1 1 0 0 1 1 1 1 Ethylbenzene dehydrogenase EB_dh PF09459.8 001360204.1_38123001_1 - 5.4e-26 91.9 0.4 6.6e-26 91.6 0.4 1.1 1 0 0 1 1 1 1 Ethylbenzene dehydrogenase Fip1 PF05182.11 001360201.1_39028001_3 - 3.1e-20 71.2 1.7 7.7e-20 70.0 1.7 1.7 1 0 0 1 1 1 1 Fip1 motif Fip1 PF05182.11 001360191.1_48927001_3 - 1.7e-17 62.4 3.9 2.2e-17 62.2 1.5 2.4 2 0 0 2 2 2 1 Fip1 motif Methyltransf_29 PF03141.14 001360326.1_03926001_2 - 6.4e-177 589.0 0.0 8e-177 588.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.10 001360326.1_03926001_2 - 8.7e-09 35.8 0.0 1.8e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.4 001360326.1_03926001_2 - 7.5e-06 26.5 0.0 0.00049 20.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.10 001360326.1_03926001_2 - 0.13 12.9 0.4 23 5.6 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain Wyosine_form PF08608.10 001360330.1_48925001_3 - 2.8e-27 94.7 0.1 5.1e-27 93.9 0.1 1.5 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.19 001360330.1_48925001_3 - 2.2e-26 93.1 0.0 4e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.23 001360330.1_48925001_3 - 2.1e-24 86.2 0.0 4.2e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.5 001360330.1_48925001_3 - 0.012 15.8 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain Methyltransf_29 PF03141.14 001360323.1_38126001_1 - 1.5e-174 581.1 0.0 2e-174 580.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.10 001360323.1_38126001_1 - 2e-10 41.0 0.0 2.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.4 001360323.1_38126001_1 - 2.1e-06 28.2 0.0 0.00035 21.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.4 001360323.1_38126001_1 - 0.0018 17.9 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.4 001360323.1_38126001_1 - 0.0019 18.0 0.0 1.3 8.8 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_8 PF05148.13 001360323.1_38126001_1 - 0.0027 17.5 0.0 5.1 6.8 0.0 3.0 3 0 0 3 3 3 2 Hypothetical methyltransferase LysE PF01810.16 001360323.1_38126001_1 - 0.031 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 LysE type translocator Wyosine_form PF08608.10 001360324.1_38124001_3 - 1.1e-27 96.0 0.0 2.2e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.19 001360324.1_38124001_3 - 2.5e-27 96.1 0.1 2.4e-25 89.7 0.0 2.4 2 0 0 2 2 2 2 Radical SAM superfamily Flavodoxin_1 PF00258.23 001360324.1_38124001_3 - 1.9e-07 31.2 0.4 4.5e-07 30.1 0.4 1.7 1 0 0 1 1 1 1 Flavodoxin Methyltransf_29 PF03141.14 001360329.1_48926001_2 - 1.8e-176 587.5 0.0 2.3e-176 587.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.10 001360329.1_48926001_2 - 2.4e-10 40.7 0.0 2.2e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.4 001360329.1_48926001_2 - 4e-07 30.5 0.0 5.5e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.4 001360329.1_48926001_2 - 0.0019 18.0 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.4 001360329.1_48926001_2 - 0.006 16.2 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_8 PF05148.13 001360329.1_48926001_2 - 0.035 13.8 0.1 1.5 8.5 0.0 2.8 2 1 0 2 2 2 0 Hypothetical methyltransferase LysE PF01810.16 001360329.1_48926001_2 - 0.049 13.0 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 LysE type translocator Flavodoxin_1 PF00258.23 001360325.1_03924001_1 - 3.5e-28 98.5 0.0 6.7e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Wyosine_form PF08608.10 001360325.1_03924001_1 - 1.1e-27 96.0 0.1 2.3e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.19 001360325.1_03924001_1 - 1.9e-25 90.0 0.0 3.9e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_5 PF12724.5 001360325.1_03924001_1 - 0.0017 18.5 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin domain EB_dh PF09459.8 001360198.1_06624001_3 - 8.3e-25 88.0 0.9 1e-24 87.7 0.9 1.1 1 0 0 1 1 1 1 Ethylbenzene dehydrogenase Myb_DNA-binding PF00249.29 001326832.1_24423001_2 - 1.2e-34 118.1 2.8 4.7e-17 61.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001326832.1_24423001_2 - 1.1e-21 76.6 0.7 2.8e-12 46.5 0.1 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.8 001326832.1_24423001_2 - 0.00077 19.3 0.0 0.44 10.5 0.0 2.8 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.3 001326832.1_24423001_2 - 0.015 15.0 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_2 PF08914.9 001326832.1_24423001_2 - 0.021 14.9 0.0 5.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Rap1 Myb domain Rap1_C PF11626.6 001326832.1_24423001_2 - 0.1 12.5 0.4 1.1 9.2 0.1 2.5 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PTPLA PF04387.12 001360627.1_01023001_2 - 4.6e-62 208.5 4.7 7.5e-62 207.8 4.7 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PTPLA PF04387.12 001360631.1_39023001_2 - 2.2e-63 212.8 4.7 2.2e-63 212.8 4.7 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Flavodoxin_1 PF00258.23 001360634.1_35325001_2 - 1.1e-28 100.0 0.0 2.3e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Radical_SAM PF04055.19 001360634.1_35325001_2 - 2.6e-27 96.1 0.0 4.3e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.10 001360634.1_35325001_2 - 6.1e-27 93.6 0.0 1.3e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation NOA36 PF06524.10 001360634.1_35325001_2 - 3.9 6.6 7.6 7.4 5.7 7.6 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.7 001360634.1_35325001_2 - 4.7 6.1 8.1 6.8 5.6 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Prenyltrans PF00432.19 001360626.1_01023001_2 - 2.5e-44 148.5 16.6 1.4e-17 63.0 0.1 6.7 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.4 001360626.1_01023001_2 - 5.7e-05 22.2 0.0 0.12 11.3 0.0 3.3 1 1 2 3 3 3 2 Squalene-hopene cyclase N-terminal domain LRS4 PF10422.7 001360626.1_01023001_3 - 1 8.7 4.8 1.7 8.0 4.8 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Methyltransf_29 PF03141.14 001360636.1_48025001_1 - 1.5e-175 584.5 0.0 1.8e-175 584.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.10 001360636.1_48025001_1 - 1.8e-08 34.8 0.0 6.4e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.4 001360636.1_48025001_1 - 3.9e-05 24.2 0.0 0.0007 20.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.4 001360636.1_48025001_1 - 0.0042 16.9 0.0 0.088 12.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.4 001360636.1_48025001_1 - 0.092 12.4 0.0 0.89 9.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain LysE PF01810.16 001360636.1_48025001_1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 LysE type translocator Wyosine_form PF08608.10 001360637.1_48025001_2 - 3.2e-27 94.5 0.1 5.9e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.19 001360637.1_48025001_2 - 1.4e-25 90.5 0.0 2.5e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.23 001360637.1_48025001_2 - 5.5e-22 78.4 0.0 1.1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.5 001360637.1_48025001_2 - 0.01 16.0 0.0 0.032 14.3 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain PTPLA PF04387.12 001360623.1_48023001_3 - 3.8e-62 208.7 5.3 6.1e-62 208.1 5.3 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PTPLA PF04387.12 001360621.1_48923001_2 - 1.5e-62 210.1 6.1 3.1e-62 209.0 6.1 1.6 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Prenyltrans PF00432.19 001360630.1_39023001_2 - 4.7e-42 141.3 19.7 3.7e-18 64.8 0.5 6.7 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.4 001360630.1_39023001_2 - 0.00079 18.5 0.1 0.039 12.9 0.0 3.0 2 1 1 3 3 3 1 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.19 001360618.1_48923001_3 - 2.9e-43 145.1 11.6 4.2e-16 58.2 0.2 6.9 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.4 001360618.1_48923001_3 - 0.004 16.2 0.0 0.15 11.1 0.0 2.9 1 1 2 3 3 3 1 Squalene-hopene cyclase N-terminal domain 2OG-FeII_Oxy_2 PF13532.4 153803.1_53724120_1 - 2.3e-11 44.2 0.3 8.7e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily DUF1644 PF07800.10 001151183.1_53724001_3 - 9.5e-51 172.1 14.9 2.7e-29 102.3 2.2 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1644) zf-Di19 PF05605.10 001151183.1_53724001_3 - 0.27 11.4 13.8 0.36 11.0 0.2 3.8 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_19 PF00182.17 001320070.1_12723001_2 - 2.2e-108 361.3 0.3 2.7e-108 361.1 0.3 1.1 1 0 0 1 1 1 1 Chitinase class I Glyco_hydro_18 PF00704.26 001309690.1_12223001_1 - 2.9e-29 102.6 0.5 4.6e-28 98.7 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Asn_synthase PF00733.19 001361146.1_48926001_1 - 3.3e-15 56.5 2.7 3.6e-09 36.6 0.5 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.4 001361146.1_48926001_1 - 2.2e-08 34.0 0.0 4.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001361146.1_48926001_1 - 0.015 15.4 0.0 0.051 13.6 0.0 1.9 2 1 0 2 2 2 0 Glutamine amidotransferase domain Asn_synthase PF00733.19 001361140.1_39025001_3 - 6.3e-16 58.8 1.4 1.2e-07 31.7 0.1 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.4 001361140.1_39025001_3 - 3.5e-10 39.7 0.0 7.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001361140.1_39025001_3 - 0.00055 20.0 0.0 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain Asn_synthase PF00733.19 001361138.1_01025001_2 - 4.2e-15 56.1 2.8 1.7e-08 34.4 0.4 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.4 001361138.1_01025001_2 - 3.7e-10 39.6 0.0 9.5e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001361138.1_01025001_2 - 0.00041 20.4 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Zein PF01559.14 152430.1_53723120_3 - 8.8e-90 300.3 68.3 1.1e-89 300.0 68.3 1.1 1 0 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 152177.1_53722120_2 - 3.9e-97 324.4 71.4 4.6e-97 324.2 71.4 1.1 1 0 0 1 1 1 1 Zein seed storage protein DDE_Tnp_IS66_C PF13817.4 152177.1_53722120_2 - 0.23 11.5 2.9 36 4.5 0.0 3.8 3 1 0 3 3 3 0 IS66 C-terminal element Zds_C PF08632.8 152177.1_53722120_2 - 8.1 6.2 11.5 0.52 10.0 0.2 3.4 4 0 0 4 4 4 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term TAF8_C PF10406.7 154558.1_48023120_1 - 1.9e-12 47.4 0.5 3.7e-12 46.5 0.5 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term TAF8_C PF10406.7 154560.1_48924120_2 - 2.4e-17 63.1 0.7 6.1e-17 61.8 0.7 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term TAF8_C PF10406.7 154557.1_39025120_3 - 2.7e-17 62.9 0.2 2.7e-17 62.9 0.2 1.9 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.11 154557.1_39025120_3 - 5.9e-16 58.1 0.1 9.2e-16 57.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.7 154555.1_01025120_1 - 1.8e-16 60.3 0.1 1.8e-16 60.3 0.1 1.8 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.11 154555.1_01025120_1 - 2.7e-16 59.2 0.1 4.3e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated Aminotran_1_2 PF00155.19 001293270.1_44323001_1 - 8.3e-106 354.1 0.0 1e-105 353.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001293270.1_44323001_1 - 0.0091 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase p450 PF00067.20 001281235.1_53024001_1 - 2.9e-114 382.2 0.0 3.6e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SusD-like PF12741.5 001281235.1_53024001_1 - 0.045 12.5 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein zf-C2H2 PF00096.24 001301909.1_07123001_1 - 1.6e-14 53.3 30.4 0.00052 20.2 0.5 5.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001301909.1_07123001_1 - 1.2e-12 47.4 27.8 0.01 16.5 0.5 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001301909.1_07123001_1 - 1.9e-05 24.7 36.1 0.0047 17.2 2.6 6.5 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_aberr PF17017.3 001301909.1_07123001_1 - 0.001 19.1 18.2 0.77 9.8 0.2 4.9 2 1 3 5 5 5 3 Aberrant zinc-finger FOXP-CC PF16159.3 001301909.1_07123001_1 - 0.014 15.9 14.8 0.24 11.9 0.1 5.4 2 2 4 6 6 6 0 FOXP coiled-coil domain IBR PF01485.19 001301909.1_07123001_1 - 0.17 12.0 7.2 7.9 6.7 0.2 3.8 2 1 2 4 4 4 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.6 001301909.1_07123001_1 - 0.37 11.0 11.7 25 5.2 0.0 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.10 001301909.1_07123001_1 - 2.1 9.0 18.2 2.9 8.5 1.4 5.0 2 1 3 5 5 5 0 CHORD zf-CGNR PF11706.6 001301909.1_07123001_1 - 2.7 7.8 10.6 1.6 8.5 0.1 4.1 5 0 0 5 5 5 0 CGNR zinc finger bHLH-MYC_N PF14215.4 001302566.1_35125001_1 - 7.5e-53 179.2 0.0 1.9e-52 177.9 0.0 1.7 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 001302566.1_35125001_1 - 4.9e-12 45.5 0.1 1.2e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain U3_snoRNA_assoc PF08297.9 001302566.1_35125001_1 - 7 7.3 6.3 0.54 10.9 0.6 2.2 2 0 0 2 2 2 0 U3 snoRNA associated IF4E PF01652.16 001302572.1_35122001_1 - 2.7e-52 176.6 4.4 3.2e-52 176.4 4.4 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HMG_box PF00505.17 001302572.1_35122001_1 - 0.028 14.7 0.8 0.059 13.7 0.8 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Pyrid_oxidase_2 PF13883.4 001309658.1_12224001_3 - 1.8e-18 67.0 0.0 4.7e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.18 001309658.1_12224001_3 - 2.3e-08 34.0 0.0 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Gp_dh_C PF02800.18 001302327.1_45323001_2 - 7.3e-66 220.5 0.4 9.9e-66 220.0 0.4 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001302327.1_45323001_2 - 4.8e-31 107.0 0.0 1.3e-30 105.6 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Myb_DNA-binding PF00249.29 001303064.1_05524001_3 - 2.5e-32 110.6 1.9 3.1e-15 55.9 0.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001303064.1_05524001_3 - 4.1e-20 71.6 0.6 1e-09 38.3 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain LCE PF14672.4 001303064.1_05524001_3 - 0.42 11.1 7.1 1.1 9.8 7.1 1.7 1 0 0 1 1 1 0 Late cornified envelope MIP PF00230.18 001293256.1_44323001_1 - 3.2e-83 278.8 7.9 4.1e-83 278.4 7.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Mis12 PF05859.10 001302589.1_35123001_2 - 6.7e-20 71.4 0.3 1.6e-19 70.2 0.1 1.6 2 0 0 2 2 2 1 Mis12 protein Taxilin PF09728.7 001302589.1_35123001_2 - 0.017 14.3 3.0 0.028 13.6 3.0 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Dor1 PF04124.10 001302589.1_35123001_2 - 0.081 11.5 2.5 0.16 10.5 2.5 1.4 1 0 0 1 1 1 0 Dor1-like family Spc24 PF08286.9 001302589.1_35123001_2 - 0.42 10.7 4.2 2.2 8.5 2.6 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.12 001302589.1_35123001_2 - 0.82 9.3 5.0 1.9 8.1 5.0 1.6 1 0 0 1 1 1 0 IncA protein Syntaxin_2 PF14523.4 001302589.1_35123001_2 - 1.2 9.4 3.6 1.4 9.2 0.3 2.6 2 1 2 4 4 4 0 Syntaxin-like protein Chloroa_b-bind PF00504.19 001302316.1_45323001_1 - 4e-43 147.6 0.0 5.8e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2391 PF09622.8 001302316.1_45323001_1 - 0.13 11.4 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) Actin PF00022.17 001302286.1_45323001_1 - 5.3e-148 492.8 0.0 1.9e-147 491.0 0.0 1.7 1 1 0 1 1 1 1 Actin Ras PF00071.20 001302574.1_35123001_1 - 1.1e-49 168.0 0.0 1.4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001302574.1_35123001_1 - 2.8e-29 101.6 0.0 4.6e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001302574.1_35123001_1 - 5.8e-11 42.0 0.0 8.4e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.20 001302574.1_35123001_1 - 2.3e-05 24.6 0.1 9.4e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.21 001302574.1_35123001_1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pox_A32 PF04665.10 001302574.1_35123001_1 - 0.023 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.4 001302574.1_35123001_1 - 0.067 12.8 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.11 001302574.1_35123001_1 - 0.071 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 KaiC DUF258 PF03193.14 001302574.1_35123001_1 - 0.074 12.8 0.0 9.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 F-box-like PF12937.5 001309678.1_12222001_1 - 1.3e-06 28.0 0.3 2.5e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001309678.1_12222001_1 - 5.9e-06 25.9 0.3 1.3e-05 24.8 0.3 1.6 1 0 0 1 1 1 1 F-box domain LysM PF01476.18 001309678.1_12222001_1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 LysM domain KNOX2 PF03791.11 001293261.1_44323001_3 - 1.4e-24 85.4 0.9 2.7e-24 84.5 0.9 1.5 1 0 0 1 1 1 1 KNOX2 domain KNOX1 PF03790.11 001293261.1_44323001_3 - 2.2e-21 75.2 0.1 3.8e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 KNOX1 domain Homeobox_KN PF05920.9 001293261.1_44323001_3 - 2.5e-17 62.3 2.2 5.1e-17 61.4 2.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain ELK PF03789.11 001293261.1_44323001_3 - 2.5e-07 30.5 0.3 4.9e-07 29.5 0.3 1.5 1 0 0 1 1 1 1 ELK domain Homeobox PF00046.27 001293261.1_44323001_3 - 1.3e-06 27.9 1.3 2.5e-06 27.0 1.3 1.5 1 0 0 1 1 1 1 Homeobox domain AMP-binding PF00501.26 001302584.1_35124001_2 - 9.8e-96 320.8 0.0 1.2e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001302584.1_35124001_2 - 3.2e-19 69.6 0.3 1.5e-18 67.4 0.3 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_S24 PF00717.21 001302584.1_35124001_2 - 0.084 12.7 0.1 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Peptidase S24-like Sod_Cu PF00080.18 001309708.1_12222001_1 - 3.1e-48 163.4 3.7 4e-48 163.0 3.7 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chloroa_b-bind PF00504.19 001302294.1_45323001_1 - 4.2e-54 183.3 0.0 5.3e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein GMC_oxred_N PF00732.17 001293255.1_44324001_1 - 1.9e-30 106.1 0.0 7.2e-30 104.2 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.11 001293255.1_44324001_1 - 9.7e-25 87.6 0.0 1.8e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.4 001293255.1_44324001_1 - 0.0054 16.8 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.12 001293255.1_44324001_1 - 0.0075 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001293255.1_44324001_1 - 0.0095 15.5 0.2 0.026 14.0 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.10 001293255.1_44324001_1 - 0.038 12.9 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DUF4536 PF15055.4 001293255.1_44324001_1 - 1.6 8.9 3.3 0.7 10.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) FLO_LFY PF01698.14 001305823.1_01623001_1 - 1.4e-176 587.2 5.6 2.3e-176 586.5 5.6 1.3 1 1 0 1 1 1 1 Floricaula / Leafy protein Gly_rich PF12810.5 001305823.1_01623001_1 - 0.022 14.5 3.9 0.03 14.1 3.9 1.1 1 0 0 1 1 1 0 Glycine rich protein AA_kinase PF00696.26 001305823.1_01623001_1 - 0.12 11.8 0.3 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 Amino acid kinase family Pyr_redox_3 PF13738.4 001280034.1_22823001_1 - 8.3e-25 87.5 0.0 8e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.17 001280034.1_22823001_1 - 1.5e-24 86.2 0.1 2.1e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.4 001280034.1_22823001_1 - 1.6e-19 70.1 0.0 6.3e-16 58.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001280034.1_22823001_1 - 3.8e-15 55.8 0.0 5.1e-14 52.1 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001280034.1_22823001_1 - 3.2e-10 39.7 0.6 1.4e-05 24.4 0.0 3.1 2 1 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.25 001280034.1_22823001_1 - 5.3e-07 30.0 0.1 0.00043 20.7 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.15 001280034.1_22823001_1 - 7.1e-07 28.6 0.5 0.0069 15.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.4 001280034.1_22823001_1 - 3.7e-06 27.0 0.0 0.012 15.8 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.20 001280034.1_22823001_1 - 5.3e-06 25.6 0.0 0.058 12.3 0.1 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.22 001280034.1_22823001_1 - 1.6e-05 24.0 0.3 0.099 11.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.22 001280034.1_22823001_1 - 3.9e-05 23.3 0.0 0.099 12.1 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.10 001280034.1_22823001_1 - 0.00072 18.6 0.1 0.025 13.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.12 001280034.1_22823001_1 - 0.0012 17.5 0.2 0.07 11.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.5 001280034.1_22823001_1 - 0.0012 18.1 0.0 0.57 9.3 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.18 001280034.1_22823001_1 - 0.0044 17.0 0.1 0.25 11.3 0.1 2.9 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.4 001280034.1_22823001_1 - 0.0076 16.5 0.1 0.048 14.0 0.0 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding IlvN PF07991.10 001280034.1_22823001_1 - 0.031 13.7 0.0 0.61 9.5 0.1 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.14 001280034.1_22823001_1 - 0.056 12.9 0.0 1.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.17 001280034.1_22823001_1 - 0.067 12.4 0.1 0.72 9.1 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.4 001280034.1_22823001_1 - 0.75 9.7 3.1 17 5.2 1.0 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding BAG PF02179.14 001305266.1_22823001_1 - 3.5e-16 59.2 3.5 5.7e-16 58.6 3.5 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.21 001305266.1_22823001_1 - 5.6e-05 22.7 0.1 0.00016 21.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.4 001305266.1_22823001_1 - 0.0077 16.5 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Pyr_redox_3 PF13738.4 001280066.1_22823001_1 - 1.9e-26 92.9 0.0 1.3e-24 86.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.17 001280066.1_22823001_1 - 5.8e-18 64.5 0.1 2.6e-17 62.3 0.1 1.9 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.4 001280066.1_22823001_1 - 8.9e-18 64.4 0.1 3.3e-15 55.9 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001280066.1_22823001_1 - 1.2e-15 57.4 0.0 1.1e-11 44.4 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001280066.1_22823001_1 - 6.1e-10 39.4 0.0 3e-05 24.4 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001280066.1_22823001_1 - 5.7e-08 32.3 0.2 0.0021 17.3 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.15 001280066.1_22823001_1 - 1.4e-06 27.6 0.0 0.016 14.3 0.0 2.1 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.20 001280066.1_22823001_1 - 8.4e-06 25.0 0.0 0.021 13.8 0.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.4 001280066.1_22823001_1 - 8.9e-06 25.7 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.4 001280066.1_22823001_1 - 8.8e-05 22.4 1.1 2.8 7.8 0.4 3.9 3 1 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.22 001280066.1_22823001_1 - 0.00011 21.3 0.3 0.018 14.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.22 001280066.1_22823001_1 - 0.00014 21.4 0.1 0.31 10.5 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.12 001280066.1_22823001_1 - 0.0013 17.4 0.2 0.75 8.3 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein Shikimate_DH PF01488.18 001280066.1_22823001_1 - 0.0039 17.1 0.1 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.14 001280066.1_22823001_1 - 0.0072 15.8 0.0 0.64 9.5 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.4 001280066.1_22823001_1 - 0.016 15.5 0.9 0.026 14.9 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.10 001280066.1_22823001_1 - 0.017 14.0 0.1 0.94 8.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.17 001280066.1_22823001_1 - 0.018 14.3 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.5 001280066.1_22823001_1 - 0.025 13.8 0.2 1.8 7.7 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.16 001280066.1_22823001_1 - 0.12 12.5 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain PP-binding PF00550.23 001280071.1_22822001_2 - 4.5e-11 42.8 1.9 4.7e-11 42.8 0.5 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site PP-binding_2 PF14573.4 001280071.1_22822001_2 - 0.0001 22.3 0.1 0.00017 21.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L12_N PF16320.3 001280071.1_22822001_2 - 2.3 7.9 5.6 1.4 8.5 0.3 2.7 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain Pkinase PF00069.23 001282347.1_22823001_1 - 2.7e-65 220.2 0.0 3.2e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001282347.1_22823001_1 - 1.5e-25 89.9 0.0 1.8e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001282347.1_22823001_1 - 7.6e-05 22.0 0.0 0.037 13.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.18 001282347.1_22823001_1 - 0.0018 17.8 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.21 001282347.1_22823001_1 - 0.009 15.8 0.1 0.032 14.0 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.14 001282347.1_22823001_1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 ABC1 family Myb_DNA-binding PF00249.29 001308520.1_22822001_1 - 1.7e-32 111.1 0.6 1.8e-15 56.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001308520.1_22822001_1 - 1.4e-17 63.5 0.0 1e-08 35.2 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Epimerase PF01370.19 001305270.1_22823001_1 - 8.8e-25 87.4 0.0 1.7e-24 86.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001305270.1_22823001_1 - 7.4e-18 64.4 0.0 1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001305270.1_22823001_1 - 8e-15 55.1 0.0 1.2e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.3 001305270.1_22823001_1 - 4.4e-12 45.9 0.0 1.4e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.10 001305270.1_22823001_1 - 7.5e-12 44.8 0.0 3.9e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.11 001305270.1_22823001_1 - 1.2e-10 41.2 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.8 001305270.1_22823001_1 - 4.1e-05 23.4 0.0 6.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.23 001305270.1_22823001_1 - 0.00012 21.5 0.0 0.0013 18.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.13 001305270.1_22823001_1 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001305270.1_22823001_1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain FMO-like PF00743.17 001280023.1_22823001_1 - 1.7e-27 95.9 0.0 2.7e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 001280023.1_22823001_1 - 8.5e-26 90.8 0.0 1.3e-23 83.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 001280023.1_22823001_1 - 2.5e-15 56.3 0.0 6e-13 48.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001280023.1_22823001_1 - 1.1e-11 44.5 0.0 1.6e-08 34.1 0.0 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001280023.1_22823001_1 - 2.6e-05 24.5 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.4 001280023.1_22823001_1 - 4e-05 23.6 0.1 0.97 9.3 0.0 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.17 001280023.1_22823001_1 - 0.00027 20.2 0.1 0.0055 15.9 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.4 001280023.1_22823001_1 - 0.0023 18.0 0.1 0.0069 16.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.15 001280023.1_22823001_1 - 0.016 14.3 0.3 0.59 9.2 0.1 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.12 001280023.1_22823001_1 - 0.084 11.4 1.0 5.1 5.5 0.4 3.6 5 0 0 5 5 5 0 HI0933-like protein ApbA PF02558.14 001280023.1_22823001_1 - 0.14 11.7 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_7 PF03441.12 001280031.1_22825001_1 - 8.3e-59 198.2 0.0 1.4e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.16 001280031.1_22825001_1 - 6.3e-39 133.5 0.0 1.1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Cryptochrome_C PF12546.6 001280031.1_22825001_1 - 3.3e-29 102.0 9.6 3.3e-29 102.0 9.6 1.6 1 1 1 2 2 2 1 Blue/Ultraviolet sensing protein C terminal Y_phosphatase2 PF03162.11 001280061.1_22822001_1 - 1.5e-63 213.2 0.0 1.9e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.4 001280061.1_22822001_1 - 1.5e-07 31.5 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.25 001280061.1_22822001_1 - 0.0016 17.9 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.18 001280061.1_22822001_1 - 0.0037 16.9 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain KNOX2 PF03791.11 001280055.1_22823001_1 - 6.2e-23 80.1 0.1 1.4e-22 78.9 0.1 1.6 1 0 0 1 1 1 1 KNOX2 domain KNOX1 PF03790.11 001280055.1_22823001_1 - 3.9e-20 71.2 0.1 7.2e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 KNOX1 domain Homeobox_KN PF05920.9 001280055.1_22823001_1 - 7.3e-17 60.9 2.9 1.6e-16 59.7 2.9 1.7 1 0 0 1 1 1 1 Homeobox KN domain ELK PF03789.11 001280055.1_22823001_1 - 2.2e-11 43.3 2.2 4.9e-11 42.2 2.2 1.6 1 0 0 1 1 1 1 ELK domain Homeobox PF00046.27 001280055.1_22823001_1 - 1.7e-06 27.6 1.0 4.3e-06 26.3 0.5 2.0 1 1 1 2 2 2 1 Homeobox domain FAD_binding_7 PF03441.12 001280040.1_22825001_1 - 3.1e-62 209.4 0.0 5.7e-61 205.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.16 001280040.1_22825001_1 - 2.6e-39 134.7 0.0 4.2e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Pkinase PF00069.23 001280065.1_22824001_1 - 1.1e-67 228.1 0.0 1.7e-67 227.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280065.1_22824001_1 - 3.3e-30 105.1 0.0 4.7e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.30 001280065.1_22824001_1 - 4.3e-25 85.2 5.0 1.9e-05 23.7 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001280065.1_22824001_1 - 4.8e-23 79.5 6.8 2.1e-05 23.7 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001280065.1_22824001_1 - 4.6e-21 72.8 2.2 6.1e-05 22.5 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001280065.1_22824001_1 - 1.2e-20 73.6 3.0 1.3e-09 38.2 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001280065.1_22824001_1 - 4.1e-15 55.1 4.3 3.2e-06 26.7 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair Kinase-like PF14531.4 001280065.1_22824001_1 - 5.1e-07 29.1 0.0 7.2e-06 25.4 0.0 2.3 1 1 1 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.7 001280065.1_22824001_1 - 1.9e-06 28.0 5.5 0.00025 21.2 0.0 3.4 3 1 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.21 001280065.1_22824001_1 - 0.00015 21.7 0.4 0.1 12.4 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.12 001280065.1_22824001_1 - 0.0013 18.0 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.5 001280065.1_22824001_1 - 0.059 13.2 6.1 5.3 6.9 1.7 3.7 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand BAG PF02179.14 001305271.1_22822001_1 - 2.2e-15 56.7 4.8 2.2e-15 56.7 4.8 1.6 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.21 001305271.1_22822001_1 - 2.8e-08 33.2 0.0 7.3e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.4 001305271.1_22822001_1 - 0.0011 19.2 0.1 0.0067 16.7 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin-like domain FMO-like PF00743.17 001280081.1_22825001_3 - 3.8e-28 98.1 0.0 6.1e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 001280081.1_22825001_3 - 3.7e-25 88.7 0.0 9.6e-22 77.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 001280081.1_22825001_3 - 3.6e-16 59.1 0.0 1.1e-12 47.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001280081.1_22825001_3 - 3.4e-12 46.1 0.0 1.5e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001280081.1_22825001_3 - 3.6e-06 26.3 0.0 0.00016 21.0 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.4 001280081.1_22825001_3 - 2.9e-05 24.0 0.2 1.6 8.6 0.1 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.25 001280081.1_22825001_3 - 7.7e-05 23.0 0.0 0.36 11.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001280081.1_22825001_3 - 7.9e-05 22.7 0.0 0.00021 21.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001280081.1_22825001_3 - 0.0016 18.0 0.0 0.11 12.0 0.0 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.15 001280081.1_22825001_3 - 0.0043 16.2 0.1 0.035 13.2 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.18 001280081.1_22825001_3 - 0.03 14.3 0.0 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.22 001280081.1_22825001_3 - 0.035 13.3 0.0 4.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.12 001280081.1_22825001_3 - 0.058 11.9 0.1 0.31 9.6 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.20 001280081.1_22825001_3 - 0.093 11.7 0.0 6.2 5.6 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.22 001280081.1_22825001_3 - 0.12 11.3 0.1 0.39 9.6 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain YjeF_N PF03853.13 001280081.1_22825001_3 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Pyr_redox_3 PF13738.4 001280024.1_22825001_3 - 2.3e-32 112.3 0.0 2.5e-29 102.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.17 001280024.1_22825001_3 - 5.9e-27 94.2 0.0 1.1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.4 001280024.1_22825001_3 - 5.9e-17 61.7 0.1 9.6e-14 51.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001280024.1_22825001_3 - 7.5e-13 48.2 0.0 2e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001280024.1_22825001_3 - 0.00013 22.0 0.0 0.0003 20.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.17 001280024.1_22825001_3 - 0.00022 20.5 0.1 0.001 18.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.25 001280024.1_22825001_3 - 0.0029 18.0 0.0 2.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001280024.1_22825001_3 - 0.0092 14.6 0.3 0.79 8.2 0.1 3.2 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_9 PF13454.4 001280024.1_22825001_3 - 0.01 15.7 0.2 10 6.0 0.1 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.22 001280024.1_22825001_3 - 0.048 13.1 0.0 0.7 9.3 0.0 2.6 4 0 0 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.20 001280024.1_22825001_3 - 0.052 12.5 0.0 14 4.5 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.15 001280024.1_22825001_3 - 0.056 12.5 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.10 001280024.1_22825001_3 - 0.075 11.9 0.1 5.5 5.8 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.14 001280024.1_22825001_3 - 0.15 11.6 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.19 001305268.1_22823001_1 - 1.6e-24 86.5 0.0 2.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001305268.1_22823001_1 - 2.7e-17 62.5 0.0 4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001305268.1_22823001_1 - 1.7e-15 57.3 0.0 2.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.3 001305268.1_22823001_1 - 5.3e-12 45.6 0.0 7.5e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.11 001305268.1_22823001_1 - 5e-11 42.5 0.0 7.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.10 001305268.1_22823001_1 - 1.9e-09 37.0 0.0 1.4e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.23 001305268.1_22823001_1 - 0.00065 19.1 0.0 0.0045 16.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase DUF1731 PF08338.9 001305268.1_22823001_1 - 0.05 13.3 0.1 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Transferase PF02458.13 001308525.1_22823001_1 - 6.3e-62 209.5 0.0 7.4e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Transferase family FMO-like PF00743.17 001280053.1_22823001_1 - 1.3e-30 106.2 0.0 3.6e-30 104.7 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 001280053.1_22823001_1 - 1.9e-27 96.2 0.0 4.2e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 001280053.1_22823001_1 - 6.4e-17 61.6 0.0 4e-13 49.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001280053.1_22823001_1 - 1.4e-13 50.7 0.0 3.3e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001280053.1_22823001_1 - 4.3e-06 26.1 0.0 8.1e-05 21.9 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.4 001280053.1_22823001_1 - 1.2e-05 25.3 0.0 4.4e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.25 001280053.1_22823001_1 - 7.2e-05 23.1 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.15 001280053.1_22823001_1 - 0.00011 21.4 0.5 0.008 15.3 0.1 2.7 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.4 001280053.1_22823001_1 - 0.00019 21.3 0.1 1.4 8.8 0.1 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.20 001280053.1_22823001_1 - 0.00067 18.7 0.1 0.55 9.1 0.0 3.3 4 0 0 4 4 4 1 Glucose inhibited division protein A DAO PF01266.22 001280053.1_22823001_1 - 0.00069 19.2 0.1 0.15 11.6 0.2 3.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase Amino_oxidase PF01593.22 001280053.1_22823001_1 - 0.0013 17.9 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.12 001280053.1_22823001_1 - 0.0022 16.6 0.5 0.025 13.2 0.2 2.7 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_2 PF00890.22 001280053.1_22823001_1 - 0.0023 17.0 0.1 0.017 14.1 0.3 2.2 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.18 001280053.1_22823001_1 - 0.0082 16.1 0.0 1.9 8.4 0.0 3.4 4 0 0 4 4 3 1 Shikimate / quinate 5-dehydrogenase DUF1265 PF06887.12 001280053.1_22823001_1 - 0.0088 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1265) NAD_binding_7 PF13241.4 001280053.1_22823001_1 - 0.012 15.9 0.0 0.065 13.6 0.0 2.3 1 1 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.5 001280053.1_22823001_1 - 0.097 11.9 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.16 001280053.1_22823001_1 - 0.15 12.2 0.0 6.8 6.9 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Myb_DNA-binding PF00249.29 001280049.1_22822001_1 - 3.3e-30 103.9 2.8 2.8e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001280049.1_22822001_1 - 1.1e-19 70.3 0.3 9e-12 44.9 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001280049.1_22822001_1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Myb DNA-binding like Bet_v_1 PF00407.17 001282346.1_22822001_1 - 3.7e-47 159.9 1.1 4.7e-47 159.5 1.1 1.1 1 0 0 1 1 1 1 Pathogenesis-related protein Bet v I family ubiquitin PF00240.21 001308770.1_27121001_1 - 1.7e-34 117.2 0.4 2.2e-34 116.9 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.15 001308770.1_27121001_1 - 7e-32 108.9 9.9 1e-31 108.3 9.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.6 001308770.1_27121001_1 - 9.4e-17 60.5 0.6 1.5e-16 59.8 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001308770.1_27121001_1 - 2.4e-05 24.6 0.1 0.00011 22.5 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.4 001308770.1_27121001_1 - 0.0085 16.1 0.0 0.017 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-C4pol PF14260.4 001308770.1_27121001_1 - 0.011 16.1 0.7 0.018 15.3 0.7 1.3 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DUF2407 PF10302.7 001308770.1_27121001_1 - 0.021 15.2 0.1 0.024 15.1 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Thioredoxin PF00085.18 001317282.1_52922001_1 - 4.9e-18 64.8 0.0 4.6e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_9 PF14595.4 001317282.1_52922001_1 - 1.2e-06 28.2 0.0 0.00029 20.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.4 001317282.1_52922001_1 - 9.2e-05 22.6 0.3 0.61 10.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.4 001317282.1_52922001_1 - 0.00069 19.9 0.2 0.26 11.6 0.1 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.9 001317282.1_52922001_1 - 0.0064 16.3 0.1 3.3 7.6 0.0 2.3 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE DIM1 PF02966.14 001317282.1_52922001_1 - 0.0076 15.9 0.9 2.4 7.8 0.1 2.2 2 0 0 2 2 2 2 Mitosis protein DIM1 CD52 PF15116.4 001317282.1_52922001_2 - 0.018 14.9 1.5 0.049 13.5 1.5 1.8 1 0 0 1 1 1 0 CAMPATH-1 antigen EIN3 PF04873.11 001317296.1_52925001_2 - 1.7e-129 430.4 8.7 2.3e-129 429.9 8.7 1.2 1 0 0 1 1 1 1 Ethylene insensitive 3 DUF2841 PF11001.6 001317296.1_52925001_2 - 0.0076 16.2 3.4 0.0076 16.2 3.4 3.3 2 2 1 3 3 3 1 Protein of unknown function (DUF2841) Actin PF00022.17 001253344.1_24123001_2 - 1.2e-34 119.6 0.0 1.6e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Actin Tyrosinase PF00264.18 001317978.1_47924001_3 - 2.4e-35 122.7 4.0 5.7e-34 118.2 4.0 2.4 1 1 0 1 1 1 1 Common central domain of tyrosinase PPO1_KFDV PF12143.6 001317978.1_47924001_3 - 7.1e-33 113.3 0.3 1.2e-32 112.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF_B2219) PPO1_DWL PF12142.6 001317978.1_47924001_3 - 3.2e-22 77.9 1.2 6.8e-22 76.9 1.2 1.6 1 0 0 1 1 1 1 Polyphenol oxidase middle domain Glyco_hydro_1 PF00232.16 001294054.1_29824001_1 - 5e-165 549.2 4.0 6.3e-165 548.8 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Peptidase_M16 PF00675.18 001297465.1_14824001_1 - 1.2e-56 190.7 0.2 1.9e-56 190.1 0.2 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001297465.1_14824001_1 - 1e-38 133.1 0.0 8.2e-37 126.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain M16C_assoc PF08367.9 001297465.1_14824001_1 - 0.00047 19.2 0.2 0.00094 18.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Pkinase PF00069.23 001301676.1_42024001_1 - 5.6e-44 150.4 0.0 7.1e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001301676.1_42024001_1 - 1.1e-42 145.9 0.0 1.5e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRRNT_2 PF08263.10 001301676.1_42024001_1 - 3.7e-09 36.6 1.7 3.7e-09 36.6 1.7 1.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001301676.1_42024001_1 - 8.9e-06 25.8 15.3 0.0069 16.6 1.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001301676.1_42024001_1 - 4.3e-05 23.1 6.9 0.025 14.2 0.4 2.6 2 0 0 2 2 2 2 Leucine rich repeat APH PF01636.21 001301676.1_42024001_1 - 0.0003 20.7 0.1 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family SKG6 PF08693.8 001301676.1_42024001_1 - 0.03 13.6 0.4 0.056 12.7 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kinase-like PF14531.4 001301676.1_42024001_1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.14 001301676.1_42024001_1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 ABC1 family LRR_1 PF00560.31 001301676.1_42024001_1 - 0.99 10.0 13.9 8.8 7.1 0.1 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat K-box PF01486.15 001280037.1_22822001_1 - 3.9e-27 94.1 14.2 3.9e-27 94.1 14.2 1.9 2 0 0 2 2 2 1 K-box region SRF-TF PF00319.16 001280037.1_22822001_1 - 1e-26 92.0 0.1 2.1e-26 91.0 0.1 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribosomal_L7Ae PF01248.24 001280037.1_22822001_1 - 0.043 13.4 0.1 0.092 12.4 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF572 PF04502.11 001280037.1_22822001_1 - 0.14 11.6 9.0 0.17 11.2 9.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) HicB-like_2 PF15970.3 001280037.1_22822001_1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Acetyltransf_11 PF13720.4 001280037.1_22822001_1 - 0.29 11.5 6.7 0.13 12.6 1.2 2.8 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Mnd1 PF03962.13 001280037.1_22822001_1 - 0.32 10.7 14.2 0.55 9.9 14.2 1.4 1 0 0 1 1 1 0 Mnd1 family Speriolin_C PF15059.4 001280037.1_22822001_1 - 0.36 10.8 3.8 0.24 11.4 0.2 2.0 2 0 0 2 2 2 0 Speriolin C-terminus bZIP_1 PF00170.19 001280037.1_22822001_1 - 0.83 9.7 16.1 0.62 10.1 4.8 3.2 2 2 1 3 3 3 0 bZIP transcription factor DUF2203 PF09969.7 001280037.1_22822001_1 - 0.84 10.2 10.2 1.8 9.1 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) HIP1_clath_bdg PF16515.3 001280037.1_22822001_1 - 0.89 10.1 17.3 1.4 9.4 7.4 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1515 PF07439.9 001280037.1_22822001_1 - 1.1 9.2 6.6 0.45 10.4 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) FUSC PF04632.10 001280037.1_22822001_1 - 1.1 7.6 4.9 1.7 7.0 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HAUS6_N PF14661.4 001280037.1_22822001_1 - 3.9 6.9 16.0 11 5.5 16.0 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ARA70 PF12489.6 001280037.1_22822001_1 - 3.9 7.5 13.7 0.22 11.6 6.0 2.2 1 1 1 2 2 2 0 Nuclear coactivator DUF972 PF06156.11 001280037.1_22822001_1 - 4.7 7.8 17.1 1.4 9.4 6.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.10 001280037.1_22822001_1 - 5.7 6.1 22.3 6.2 6.0 20.0 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 Kinetocho_Slk19 PF12709.5 001280037.1_22822001_1 - 8.8 6.7 12.5 6.6 7.1 2.8 2.7 1 1 2 3 3 3 0 Central kinetochore-associated PBP PF01161.18 001280077.1_22822001_1 - 3e-14 53.3 0.0 3.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WRKY PF03106.13 001301893.1_07122001_1 - 8.5e-25 86.8 1.8 1.3e-24 86.1 0.2 2.2 2 0 0 2 2 2 1 WRKY DNA -binding domain DASH_Dad4 PF08650.8 001301893.1_07122001_1 - 0.039 13.8 1.3 0.039 13.8 1.3 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad4 Phage_TAC_8 PF10666.7 001301893.1_07122001_1 - 0.046 13.7 0.3 0.092 12.7 0.3 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 DUF641 PF04859.10 001301893.1_07122001_1 - 0.39 10.9 8.1 0.23 11.7 0.7 3.3 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Seryl_tRNA_N PF02403.20 001301893.1_07122001_1 - 2.9 8.0 8.3 2.2 8.4 0.6 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Thaumatin PF00314.15 001301908.1_07122001_1 - 1.1e-83 280.2 8.0 1.2e-83 280.0 8.0 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.3 001301908.1_07122001_1 - 0.077 12.1 0.1 8 5.5 0.0 2.5 3 0 0 3 3 3 0 Beta-1,3-glucanase TP6A_N PF04406.12 001301912.1_07123001_1 - 1e-16 60.5 0.2 2.1e-16 59.5 0.2 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Response_reg PF00072.22 001301946.1_07123001_1 - 2e-21 76.1 0.3 3.5e-21 75.3 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain CCT PF06203.12 001301946.1_07123001_1 - 3.5e-18 65.2 9.1 6.1e-18 64.5 9.1 1.4 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.8 001301946.1_07123001_1 - 0.0086 15.8 2.1 0.015 15.0 2.1 1.4 1 0 0 1 1 1 1 Divergent CCT motif RA PF00788.21 001301946.1_07123001_1 - 0.071 13.6 0.8 0.17 12.4 0.1 1.9 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain CBFB_NFYA PF02045.13 001301946.1_07123001_1 - 0.15 12.7 5.4 0.28 11.8 5.4 1.4 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B WRKY PF03106.13 001301948.1_07123001_1 - 8.5e-49 163.6 12.3 1.1e-25 89.6 2.6 2.4 2 0 0 2 2 2 2 WRKY DNA -binding domain FAR1 PF03101.13 001301948.1_07123001_1 - 0.053 14.1 0.2 4.3 8.0 0.0 2.5 2 0 0 2 2 2 0 FAR1 DNA-binding domain ThiF PF00899.19 001301949.1_07124001_1 - 5.9e-25 87.9 0.0 1.3e-24 86.8 0.0 1.6 1 1 0 1 1 1 1 ThiF family Sep15_SelM PF08806.9 001301967.1_07122001_2 - 1.8e-23 82.4 0.2 3.3e-23 81.6 0.2 1.4 1 0 0 1 1 1 1 Sep15/SelM redox domain FMO-like PF00743.17 001301979.1_07123001_1 - 3.7e-30 104.7 0.0 6.7e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 001301979.1_07123001_1 - 3e-25 89.0 0.0 2.8e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 001301979.1_07123001_1 - 1.9e-20 73.2 0.0 9.8e-16 57.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001301979.1_07123001_1 - 2.6e-17 62.9 0.0 2.8e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.4 001301979.1_07123001_1 - 3e-07 30.4 0.0 0.16 11.8 0.0 3.4 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.4 001301979.1_07123001_1 - 4.5e-06 26.7 0.0 1.4e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.25 001301979.1_07123001_1 - 2.4e-05 24.7 0.0 0.092 13.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.15 001301979.1_07123001_1 - 0.00025 20.2 0.1 0.034 13.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.22 001301979.1_07123001_1 - 0.00026 20.6 0.8 0.038 13.5 0.0 3.3 3 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.17 001301979.1_07123001_1 - 0.00037 19.7 0.0 0.0046 16.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.12 001301979.1_07123001_1 - 0.00087 17.9 0.2 0.36 9.3 0.1 3.5 5 0 0 5 5 5 1 HI0933-like protein Amino_oxidase PF01593.22 001301979.1_07123001_1 - 0.02 14.0 0.0 4.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.20 001301979.1_07123001_1 - 0.029 13.3 0.0 22 3.9 0.0 3.1 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.22 001301979.1_07123001_1 - 0.03 13.3 0.1 0.46 9.4 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.10 001301979.1_07123001_1 - 0.12 11.2 0.6 5.7 5.7 0.0 2.9 4 0 0 4 4 4 0 Lycopene cyclase protein Shikimate_DH PF01488.18 001301979.1_07123001_1 - 0.19 11.7 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_M20 PF01546.26 001301984.1_07124001_2 - 9e-31 107.1 0.3 1.1e-30 106.7 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.12 001301984.1_07124001_2 - 1.3e-12 47.4 0.0 3e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain KNOX2 PF03791.11 001302020.1_07123001_1 - 5.9e-21 73.8 1.0 1.8e-20 72.2 1.0 1.9 1 0 0 1 1 1 1 KNOX2 domain KNOX1 PF03790.11 001302020.1_07123001_1 - 1.4e-20 72.6 0.3 3.4e-20 71.4 0.3 1.7 1 0 0 1 1 1 1 KNOX1 domain Homeobox_KN PF05920.9 001302020.1_07123001_1 - 1.4e-17 63.2 4.2 3.4e-17 61.9 3.5 2.1 2 0 0 2 2 2 1 Homeobox KN domain ELK PF03789.11 001302020.1_07123001_1 - 3.3e-11 42.8 3.8 6.4e-11 41.9 3.8 1.5 1 0 0 1 1 1 1 ELK domain Homeobox PF00046.27 001302020.1_07123001_1 - 2.3e-07 30.4 2.3 4.6e-07 29.4 1.7 1.8 1 1 1 2 2 2 1 Homeobox domain WBP-1 PF11669.6 001302020.1_07123001_1 - 0.031 14.8 1.2 0.073 13.6 1.2 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 WRKY PF03106.13 001302034.1_07122001_1 - 3e-23 81.8 6.9 5.9e-23 80.9 6.9 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.14 001302034.1_07122001_1 - 0.011 15.7 0.6 0.026 14.5 0.6 1.7 1 0 0 1 1 1 0 FLYWCH zinc finger domain NIF PF03031.16 001302034.1_07122001_1 - 0.027 14.1 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase WCOR413 PF05562.9 001302037.1_07122001_1 - 3.1e-86 287.8 3.7 3.7e-86 287.6 3.7 1.0 1 0 0 1 1 1 1 Cold acclimation protein WCOR413 Syja_N PF02383.16 001302038.1_07124001_1 - 7.2e-89 298.0 0.0 9.3e-89 297.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain AT_hook PF02178.17 001302044.1_07122001_1 - 0.00027 20.4 39.9 0.024 14.4 1.0 5.9 5 0 0 5 5 5 5 AT hook motif WRKY PF03106.13 001302045.1_07123001_1 - 1.7e-26 92.2 0.1 1.7e-26 92.2 0.1 2.3 2 0 0 2 2 2 1 WRKY DNA -binding domain Plant_zn_clust PF10533.7 001302045.1_07123001_1 - 4e-16 58.5 8.6 1.5e-15 56.7 8.6 2.0 1 0 0 1 1 1 1 Plant zinc cluster domain Pollen_allerg_1 PF01357.19 001302063.1_07122001_1 - 3.1e-26 91.1 0.0 5.1e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001302063.1_07122001_1 - 3.8e-17 62.2 0.1 3.8e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 Lytic transglycolase 1-cysPrx_C PF10417.7 001302063.1_07122001_1 - 0.1 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin WRKY PF03106.13 001302064.1_07122001_1 - 9e-22 77.1 1.4 9e-22 77.1 1.4 1.6 2 0 0 2 2 2 1 WRKY DNA -binding domain Pollen_allerg_1 PF01357.19 001302070.1_07122001_1 - 1.7e-16 59.9 0.0 2.6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001302070.1_07122001_1 - 4.6e-16 58.8 0.6 1.4e-15 57.2 0.0 2.1 2 1 1 3 3 3 1 Lytic transglycolase Bile_Hydr_Trans PF04775.12 001302070.1_07122001_1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region UQ_con PF00179.24 001302842.1_34422001_1 - 3.2e-51 172.6 0.0 3.8e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001302842.1_34422001_1 - 0.00011 21.7 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001302842.1_34422001_1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.24 001302843.1_34422001_1 - 2.7e-52 176.0 0.0 3.4e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001302843.1_34422001_1 - 0.0002 21.0 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001302843.1_34422001_1 - 0.044 14.0 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain peroxidase PF00141.21 001302845.1_34423001_2 - 4.1e-46 157.4 0.0 5.4e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase AP2 PF00847.18 001302846.1_34425001_1 - 1.3e-18 66.9 9.5 8.4e-09 35.4 0.6 2.4 2 0 0 2 2 2 2 AP2 domain INCA1 PF15142.4 001302846.1_34425001_1 - 0.078 12.8 1.0 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 INCA1 Phytochelatin_C PF09328.8 001302848.1_34425001_1 - 7e-124 412.2 5.8 7e-124 412.2 5.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1984) Phytochelatin PF05023.12 001302848.1_34425001_1 - 2.2e-90 301.5 0.0 4.5e-90 300.4 0.0 1.5 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.4 001302848.1_34425001_1 - 0.0059 17.0 0.2 0.49 10.8 0.0 2.4 2 0 0 2 2 2 1 Peptidase_C39 like family Peptidase_C39 PF03412.13 001302848.1_34425001_1 - 0.046 13.4 0.0 8.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase C39 family Catalase PF00199.17 001302850.1_34424001_1 - 1.1e-169 564.4 0.0 1.3e-169 564.2 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.10 001302850.1_34424001_1 - 1.2e-17 63.7 0.0 3.1e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Annexin PF00191.18 001302851.1_34423001_1 - 4.6e-70 231.5 8.1 1e-21 76.7 0.1 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.3 001302851.1_34423001_1 - 0.019 14.7 0.5 4 7.3 0.0 3.2 3 0 0 3 3 3 0 Myb DNA-binding like peroxidase PF00141.21 001302852.1_34423001_2 - 1.1e-62 211.6 0.0 1.4e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase DUF5134 PF17197.2 001302852.1_34423001_2 - 0.12 12.1 0.4 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) AOX PF01786.15 001302853.1_34423001_1 - 2.9e-79 265.5 0.5 4.4e-79 264.9 0.5 1.2 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.11 001302853.1_34423001_1 - 0.0027 17.4 0.0 0.0059 16.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 AOX PF01786.15 001302854.1_34423001_1 - 5.7e-81 271.1 0.3 8.7e-81 270.5 0.3 1.2 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.11 001302854.1_34423001_1 - 0.0039 16.8 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 GSHPx PF00255.17 001302855.1_34422001_2 - 7.3e-43 144.4 0.3 1e-42 144.0 0.3 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 001302855.1_34422001_2 - 1.6e-08 34.4 0.1 4.4e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001302855.1_34422001_2 - 8.4e-07 28.6 0.0 3.4e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.12 001302855.1_34422001_2 - 0.025 14.3 0.4 0.15 11.7 0.4 2.0 1 1 0 1 1 1 0 SCO1/SenC UQ_con PF00179.24 001302858.1_34422001_1 - 3e-52 175.8 0.0 3.8e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001302858.1_34422001_1 - 0.00025 20.6 0.0 0.00034 20.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001302858.1_34422001_1 - 0.047 13.8 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain DOG1 PF14144.4 001302859.1_34423001_1 - 3.4e-31 107.1 0.0 1.4e-30 105.2 0.0 2.2 1 0 0 1 1 1 1 Seed dormancy control bZIP_1 PF00170.19 001302859.1_34423001_1 - 5.4e-08 32.7 10.8 1.4e-07 31.3 10.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001302859.1_34423001_1 - 1.3e-07 31.4 10.5 4.4e-07 29.7 10.5 1.9 1 0 0 1 1 1 1 Basic region leucine zipper IclR PF01614.16 001302859.1_34423001_1 - 0.01 15.5 0.1 0.072 12.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial transcriptional regulator ANXA2R PF15721.3 001302859.1_34423001_1 - 0.64 10.4 6.1 1.8 9.0 6.1 1.8 1 1 0 1 1 1 0 Annexin-2 receptor NTP_transferase PF00483.21 001302857.1_34425001_3 - 9.3e-81 270.9 0.0 1.2e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.22 001302857.1_34425001_3 - 0.00093 18.7 2.1 0.00093 18.7 2.1 2.7 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.10 001302857.1_34425001_3 - 0.0094 14.9 0.6 0.17 10.7 0.6 2.3 1 1 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.5 001302857.1_34425001_3 - 0.03 14.5 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain UQ_con PF00179.24 001302860.1_34422001_1 - 2.2e-52 176.3 0.0 2.7e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001302860.1_34422001_1 - 9.6e-05 22.0 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001302860.1_34422001_1 - 0.054 13.7 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Actin PF00022.17 001302972.1_08323001_1 - 2.7e-146 487.2 0.0 9.5e-146 485.4 0.0 1.7 1 1 0 1 1 1 1 Actin Cupin_1 PF00190.20 001302979.1_08324001_2 - 7.3e-70 233.3 5.4 2.6e-35 121.1 0.2 3.1 2 1 1 3 3 3 3 Cupin Cupin_2 PF07883.9 001302979.1_08324001_2 - 0.00024 20.6 0.0 0.039 13.5 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Hint_2 PF13403.4 001302979.1_08324001_2 - 0.16 12.1 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Hint domain ALMT PF11744.6 001302986.1_08323001_1 - 6e-152 506.6 2.1 3.3e-146 487.7 0.0 2.1 1 1 1 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.4 001302986.1_08323001_1 - 2.4e-10 40.6 10.7 3.6e-10 40.0 10.7 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.10 001302986.1_08323001_1 - 1.6e-09 36.8 0.1 2.7e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC-like PF12805.5 001302986.1_08323001_1 - 0.006 15.5 0.1 0.019 13.9 0.0 1.9 2 0 0 2 2 2 1 FUSC-like inner membrane protein yccS FA_desaturase_2 PF03405.12 001302993.1_08323001_1 - 7.4e-158 524.4 0.0 8.5e-158 524.2 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.15 001302993.1_08323001_1 - 0.0019 18.5 0.1 0.48 10.7 0.1 2.5 2 0 0 2 2 2 2 Rubrerythrin Ferritin PF00210.22 001302993.1_08323001_1 - 0.063 13.1 0.3 0.81 9.5 0.1 2.6 2 1 0 2 2 2 0 Ferritin-like domain EF-hand_1 PF00036.30 001304291.1_43622001_1 - 7.4e-20 68.8 6.9 2.7e-06 26.4 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001304291.1_43622001_1 - 1.9e-15 55.5 7.9 1.3e-07 30.6 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001304291.1_43622001_1 - 1.2e-14 52.7 6.2 0.0019 17.8 0.4 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001304291.1_43622001_1 - 3.2e-14 53.0 8.2 2.5e-08 34.1 0.9 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.4 001304291.1_43622001_1 - 5.8e-08 32.2 8.9 6.5e-05 22.5 0.7 3.6 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.5 001304291.1_43622001_1 - 0.00058 19.7 0.7 0.099 12.5 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001304291.1_43622001_1 - 0.02 15.0 0.5 0.02 15.0 0.5 2.9 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2247 PF10004.7 001304291.1_43622001_1 - 0.072 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Gemini_AL1 PF00799.18 001304291.1_43622001_1 - 0.094 12.8 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain SHOCT PF09851.7 001304291.1_43622001_1 - 2.7 7.7 0.0 2.7 7.7 0.0 3.4 5 0 0 5 5 5 0 Short C-terminal domain Na_H_Exchanger PF00999.19 001304296.1_43624001_1 - 1.9e-66 224.3 37.1 2.3e-66 224.0 37.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.19 001304297.1_43624001_1 - 6.4e-60 202.8 33.9 8.2e-60 202.5 33.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3995 PF13160.4 001304297.1_43624001_1 - 0.2 11.9 4.6 0.95 9.7 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) Pkinase PF00069.23 001304298.1_43623001_1 - 2.5e-68 230.2 0.0 3.3e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001304298.1_43623001_1 - 1.6e-34 119.3 0.0 2.1e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001304298.1_43623001_1 - 5e-19 68.1 0.1 9e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001304298.1_43623001_1 - 9.2e-09 34.9 0.0 6.5e-08 32.1 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001304298.1_43623001_1 - 0.00059 19.1 0.0 0.00095 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001304298.1_43623001_1 - 0.058 13.2 0.1 0.45 10.3 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.19 001304300.1_43623001_3 - 1.1e-57 194.2 0.4 1.5e-57 193.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 XET_C PF06955.10 001304300.1_43623001_3 - 3.2e-19 68.5 4.6 6.7e-19 67.4 4.6 1.6 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus Na_H_Exchanger PF00999.19 001304302.1_43624001_1 - 2.8e-58 197.4 37.3 3.7e-58 197.0 37.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ion_trans PF00520.29 001304301.1_43626001_1 - 1.1e-35 122.9 8.3 1.5e-35 122.4 8.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.5 001304301.1_43626001_1 - 7.9e-24 83.9 0.2 2.8e-13 50.1 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001304301.1_43626001_1 - 1.1e-21 76.7 2.5 3.5e-07 30.5 0.4 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) KHA PF11834.6 001304301.1_43626001_1 - 5.4e-21 74.3 0.0 1.9e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 KHA, dimerisation domain of potassium ion channel Ank_5 PF13857.4 001304301.1_43626001_1 - 1.3e-20 73.0 1.0 6.2e-09 35.9 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001304301.1_43626001_1 - 6.3e-17 59.8 3.3 6.4e-05 22.9 0.1 5.9 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.28 001304301.1_43626001_1 - 3.4e-16 58.8 7.1 1.6e-06 28.1 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat cNMP_binding PF00027.27 001304301.1_43626001_1 - 2.8e-14 52.8 0.0 5.8e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.14 001304301.1_43626001_1 - 9.2e-13 47.9 5.4 2e-12 46.8 5.4 1.6 1 0 0 1 1 1 1 Ion channel Pkinase PF00069.23 001304303.1_43624001_1 - 9.1e-75 251.3 0.0 1.3e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001304303.1_43624001_1 - 3.6e-33 110.5 10.5 7.4e-09 34.4 0.2 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001304303.1_43624001_1 - 7.8e-29 100.6 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001304303.1_43624001_1 - 1.4e-27 95.8 6.7 2.7e-14 53.2 5.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001304303.1_43624001_1 - 2e-24 83.3 7.4 1.3e-06 27.7 0.4 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.4 001304303.1_43624001_1 - 1.2e-20 72.9 13.1 1.5e-06 27.7 1.7 4.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.4 001304303.1_43624001_1 - 3.7e-20 70.3 5.7 1.9e-05 23.9 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.5 001304303.1_43624001_1 - 2.5e-08 33.7 2.0 0.003 17.3 0.1 3.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.12 001304303.1_43624001_1 - 9e-07 28.3 0.1 1.9e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001304303.1_43624001_1 - 7.3e-06 25.4 0.0 0.00098 18.4 0.0 2.9 1 1 1 2 2 2 1 Kinase-like EF-hand_9 PF14658.4 001304303.1_43624001_1 - 3e-05 24.1 0.9 0.038 14.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.7 001304303.1_43624001_1 - 0.0005 20.2 0.1 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.11 001304303.1_43624001_1 - 0.0073 16.1 0.4 5.4 6.8 0.0 3.2 1 1 2 3 3 3 1 Caleosin related protein APH PF01636.21 001304303.1_43624001_1 - 0.0076 16.1 0.0 0.028 14.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.20 001304303.1_43624001_1 - 0.071 12.6 0.1 0.071 12.6 0.1 2.5 3 0 0 3 3 3 0 RIO1 family AAA_assoc_2 PF16193.3 001304303.1_43624001_1 - 0.13 12.4 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA C-terminal domain EF-hand_1 PF00036.30 001304306.1_43622001_3 - 5.1e-17 59.9 14.8 5.6e-05 22.3 0.5 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001304306.1_43622001_3 - 3.4e-14 51.4 10.8 0.0014 18.3 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001304306.1_43622001_3 - 6e-12 44.4 15.3 9e-07 28.0 1.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001304306.1_43622001_3 - 1.1e-11 44.9 10.1 2.1e-07 31.2 1.9 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.5 001304306.1_43622001_3 - 0.00032 20.5 1.6 0.068 13.0 0.3 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.4 001304306.1_43622001_3 - 0.00052 19.6 13.1 0.0011 18.6 1.4 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.4 001304306.1_43622001_3 - 0.0032 17.6 0.2 0.06 13.6 0.0 2.5 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.7 001304306.1_43622001_3 - 0.021 15.0 2.6 0.1 12.8 1.2 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.23 001304307.1_43623001_1 - 1.3e-72 244.2 0.0 1.7e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001304307.1_43623001_1 - 1.9e-39 135.4 0.0 2.6e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001304307.1_43623001_1 - 1.3e-17 63.6 0.0 2.7e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001304307.1_43623001_1 - 3.9e-08 32.8 0.2 8.6e-07 28.4 0.0 2.6 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.12 001304307.1_43623001_1 - 0.0051 16.0 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KA1 PF02149.17 001304307.1_43623001_1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Kinase associated domain 1 APH PF01636.21 001304307.1_43623001_1 - 0.028 14.2 0.0 0.15 11.9 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.20 001304307.1_43623001_1 - 0.032 13.7 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Trimer_CC PF08954.9 001304307.1_43623001_1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Trimerisation motif Calmodulin_bind PF07887.9 001304308.1_43624001_1 - 1.8e-122 408.2 0.0 2.2e-122 407.8 0.0 1.1 1 0 0 1 1 1 1 Calmodulin binding protein-like Na_H_Exchanger PF00999.19 001304309.1_43624001_1 - 2.7e-62 210.6 34.2 3.4e-62 210.3 34.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrbC PF04956.11 001304309.1_43624001_1 - 0.05 13.7 0.1 0.05 13.7 0.1 3.3 2 1 0 2 2 2 0 TrbC/VIRB2 family DUF1705 PF08019.10 001304309.1_43624001_1 - 0.58 9.9 22.4 0.092 12.5 1.6 4.8 3 3 2 5 5 5 0 Domain of unknown function (DUF1705) RseC_MucC PF04246.10 001304309.1_43624001_1 - 3.1 7.7 15.3 1.1 9.1 0.4 4.2 2 2 2 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Aldedh PF00171.20 001304311.1_43624001_3 - 5.5e-174 578.9 0.0 6.2e-174 578.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.9 001304311.1_43624001_3 - 0.0075 15.6 0.0 0.64 9.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) SpoIIAA-like PF11964.6 001304311.1_43624001_3 - 0.0082 17.0 0.0 0.67 10.9 0.0 2.6 2 0 0 2 2 2 1 SpoIIAA-like Aldedh PF00171.20 001304314.1_43624001_1 - 6.3e-173 575.4 0.0 7.1e-173 575.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.9 001304314.1_43624001_1 - 0.00069 19.0 0.0 0.0064 15.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) SpoIIAA-like PF11964.6 001304314.1_43624001_1 - 0.00074 20.4 0.0 0.14 13.0 0.0 2.5 2 0 0 2 2 2 1 SpoIIAA-like HhH-GPD PF00730.23 001304314.1_43624001_1 - 0.14 12.5 0.0 22 5.4 0.0 2.4 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein CagA PF03507.11 001304314.1_43624001_1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 CagA exotoxin Ank_2 PF12796.5 001304315.1_43626001_3 - 3.5e-24 85.0 0.2 1.8e-13 50.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001304315.1_43626001_3 - 1.3e-22 79.7 0.1 6.2e-06 26.5 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ion_trans PF00520.29 001304315.1_43626001_3 - 4.6e-22 78.3 14.2 6.3e-22 77.8 14.2 1.2 1 0 0 1 1 1 1 Ion transport protein KHA PF11834.6 001304315.1_43626001_3 - 7.3e-21 73.9 0.0 1.5e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Ank_5 PF13857.4 001304315.1_43626001_3 - 1.4e-19 69.7 1.4 5.7e-09 36.0 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 001304315.1_43626001_3 - 8.5e-18 62.5 1.6 0.0001 22.3 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat cNMP_binding PF00027.27 001304315.1_43626001_3 - 2e-17 62.8 0.1 3.4e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ank PF00023.28 001304315.1_43626001_3 - 3.3e-17 61.9 8.6 0.00078 19.7 0.1 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ion_trans_2 PF07885.14 001304315.1_43626001_3 - 3.3e-07 30.0 6.8 8.2e-07 28.8 6.8 1.7 1 1 0 1 1 1 1 Ion channel MarR_2 PF12802.5 001304315.1_43626001_3 - 0.14 12.0 0.0 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 MarR family HLH PF00010.24 001304319.1_43622001_1 - 9.5e-10 38.2 1.1 2.5e-09 36.8 1.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF334 PF03904.11 001304319.1_43622001_1 - 0.18 11.2 3.5 0.098 12.0 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) IncA PF04156.12 001304319.1_43622001_1 - 1.1 8.9 8.6 0.96 9.1 5.2 2.0 2 0 0 2 2 2 0 IncA protein PCRF PF03462.16 001304319.1_43622001_1 - 6 6.5 8.0 2.4 7.9 3.9 2.1 1 1 0 2 2 2 0 PCRF domain EF-hand_1 PF00036.30 001304316.1_43622001_1 - 1.9e-20 70.7 10.8 1.4e-06 27.2 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.4 001304316.1_43622001_1 - 4.6e-17 60.3 6.3 0.00021 20.8 0.9 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.4 001304316.1_43622001_1 - 9.8e-15 54.7 7.4 1.3e-09 38.3 1.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001304316.1_43622001_1 - 3.2e-13 48.4 11.8 1.7e-07 30.3 0.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.4 001304316.1_43622001_1 - 5.7e-10 38.7 3.8 4.6e-05 23.0 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.5 001304316.1_43622001_1 - 0.00086 19.1 0.3 0.72 9.7 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001304316.1_43622001_1 - 0.00093 19.4 0.7 0.012 15.8 0.2 2.5 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Ion_trans PF00520.29 001304322.1_43626001_1 - 3.8e-37 127.7 16.7 5.2e-37 127.3 16.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.5 001304322.1_43626001_1 - 4.1e-23 81.6 3.0 1.1e-13 51.4 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) KHA PF11834.6 001304322.1_43626001_1 - 9.9e-21 73.5 0.0 2.3e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Ank_5 PF13857.4 001304322.1_43626001_1 - 6.6e-18 64.4 0.9 1.1e-09 38.2 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.4 001304322.1_43626001_1 - 5.7e-17 61.7 0.3 1.8e-09 37.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ion_trans_2 PF07885.14 001304322.1_43626001_1 - 1.9e-14 53.2 5.1 4.7e-14 52.0 5.1 1.7 1 0 0 1 1 1 1 Ion channel Ank_3 PF13606.4 001304322.1_43626001_1 - 9.2e-14 50.1 2.6 2e-05 24.5 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat cNMP_binding PF00027.27 001304322.1_43626001_1 - 2.4e-12 46.6 0.0 4.9e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ank PF00023.28 001304322.1_43626001_1 - 9.9e-12 44.6 6.5 7.9e-07 29.1 0.0 5.4 6 1 0 6 6 6 3 Ankyrin repeat SPC25 PF06703.9 001304322.1_43626001_1 - 0.89 9.2 8.1 2.7 7.6 1.1 3.0 3 1 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Na_H_Exchanger PF00999.19 001304325.1_43624001_1 - 9.1e-59 199.0 34.8 1.2e-58 198.7 34.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase PF00069.23 001304326.1_43623001_1 - 4.8e-71 239.1 0.0 6.3e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001304326.1_43623001_1 - 6.3e-33 114.0 0.0 8.3e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001304326.1_43623001_1 - 3.1e-20 72.0 0.0 5.9e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001304326.1_43623001_1 - 3.9e-08 32.8 0.0 2.4e-07 30.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001304326.1_43623001_1 - 0.0066 15.7 0.1 0.02 14.1 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_1 PF00036.30 001304327.1_43622001_1 - 3.3e-19 66.8 5.7 2.8e-05 23.2 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001304327.1_43622001_1 - 3e-14 51.7 6.8 4.7e-06 25.8 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001304327.1_43622001_1 - 5.8e-14 52.2 7.5 6.3e-08 32.9 0.4 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.4 001304327.1_43622001_1 - 7.7e-14 50.3 5.2 0.0019 17.8 0.4 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.4 001304327.1_43622001_1 - 3.4e-09 36.2 8.1 6.6e-05 22.5 0.7 3.7 3 2 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001304327.1_43622001_1 - 0.0063 16.7 4.3 0.0089 16.2 0.9 3.0 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001304327.1_43622001_1 - 0.0066 16.2 1.4 0.11 12.4 0.1 2.3 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF2247 PF10004.7 001304327.1_43622001_1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) HSP70 PF00012.18 001308871.1_14925001_2 - 1.7e-261 868.6 5.6 1.9e-261 868.4 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001308871.1_14925001_2 - 4e-14 52.1 0.1 2.9e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.14 001308871.1_14925001_2 - 0.072 12.7 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.16 001308871.1_14925001_2 - 0.29 10.2 2.9 0.23 10.6 0.1 2.2 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase zf-C2H2_6 PF13912.4 001279064.1_12223001_2 - 4.9e-26 90.0 15.4 1.7e-13 50.0 1.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001279064.1_12223001_2 - 2.1e-05 24.6 1.8 0.2 11.9 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.4 001279064.1_12223001_2 - 0.00028 21.3 14.7 0.0065 17.1 0.7 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001279064.1_12223001_2 - 0.0016 18.7 2.4 0.41 11.1 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-met PF12874.5 001279064.1_12223001_2 - 0.0031 17.7 6.0 0.26 11.6 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.24 001279064.1_12223001_2 - 0.033 14.5 11.0 0.39 11.1 0.6 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.5 001279064.1_12223001_2 - 0.17 12.1 6.6 0.85 9.8 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) BAG PF02179.14 001289019.1_22822001_1 - 8.3e-14 51.6 1.2 1.3e-13 51.0 1.2 1.3 1 0 0 1 1 1 1 BAG domain IQ PF00612.25 001289019.1_22822001_1 - 2.6e-05 23.5 0.3 8.9e-05 21.8 0.3 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF2205 PF10224.7 001289019.1_22822001_1 - 0.029 14.2 0.2 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) NIBRIN_BRCT_II PF16508.3 001289019.1_22822001_1 - 0.032 14.4 0.1 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein PPR_2 PF13041.4 001302517.1_35323001_1 - 7.4e-93 304.5 26.6 1.8e-17 63.1 0.5 10.1 4 3 6 10 10 10 10 PPR repeat family PPR_1 PF12854.5 001302517.1_35323001_1 - 8.4e-84 274.8 27.3 6.9e-16 57.5 0.1 11.4 10 1 1 11 11 11 10 PPR repeat PPR PF01535.18 001302517.1_35323001_1 - 2.9e-65 211.9 27.4 1e-10 41.0 0.2 12.0 11 1 1 12 12 12 11 PPR repeat PPR_3 PF13812.4 001302517.1_35323001_1 - 4.8e-39 132.1 8.9 1.7e-10 40.7 0.1 7.5 2 2 8 10 10 10 9 Pentatricopeptide repeat domain PPR_long PF17177.2 001302517.1_35323001_1 - 3.7e-12 45.9 0.0 3.4e-05 23.2 0.0 3.2 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PROPR RPM2 PF08579.9 001302517.1_35323001_1 - 0.00067 19.9 0.7 1.3 9.3 0.0 4.3 3 2 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_2 PF07719.15 001302517.1_35323001_1 - 0.0043 16.9 0.3 53 4.1 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.4 001302517.1_35323001_1 - 0.0059 17.0 0.0 2.2 8.7 0.0 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat MA3 PF02847.15 001302517.1_35323001_1 - 0.012 15.5 0.0 3.8 7.4 0.0 2.9 2 1 0 2 2 2 0 MA3 domain DUF3368 PF11848.6 001302517.1_35323001_1 - 0.018 14.7 0.1 1.1 9.0 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3368) MRP-S27 PF10037.7 001302517.1_35323001_1 - 0.022 13.6 0.6 12 4.5 0.0 4.2 3 1 2 6 6 6 0 Mitochondrial 28S ribosomal protein S27 Cys_knot PF00007.20 001302517.1_35323001_1 - 0.043 14.0 0.0 0.65 10.2 0.0 2.4 2 0 0 2 2 2 0 Cystine-knot domain Phage_TAC_10 PF10963.6 001302517.1_35323001_1 - 0.054 13.5 0.1 9.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Phage tail assembly chaperone TPR_1 PF00515.26 001302517.1_35323001_1 - 0.16 11.7 0.7 65 3.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat AP2 PF00847.18 001309654.1_12223001_1 - 5e-14 52.2 2.2 1.1e-13 51.1 2.2 1.6 1 0 0 1 1 1 1 AP2 domain Staygreen PF12638.5 001315884.1_06922001_1 - 2.3e-60 202.5 0.0 3.2e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Staygreen protein Abhydrolase_6 PF12697.5 001246884.2_48422001_2 - 8.2e-16 59.1 0.0 9.8e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001246884.2_48422001_2 - 3.1e-12 46.6 0.3 5.4e-12 45.8 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001246884.2_48422001_2 - 1.8e-08 33.8 0.2 3.5e-08 32.9 0.1 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.11 001246884.2_48422001_2 - 0.00088 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.5 001246884.2_48422001_2 - 0.0018 17.9 0.1 0.0073 15.9 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.9 001246884.2_48422001_2 - 0.027 13.7 0.1 0.06 12.5 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.13 001246884.2_48422001_2 - 0.037 13.1 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.18 001246884.2_48422001_2 - 0.058 13.4 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.12 001246884.2_48422001_2 - 0.065 12.6 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.19 001246884.2_48422001_2 - 0.07 12.5 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.11 001246884.2_48422001_2 - 0.095 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Pyridoxal_deC PF00282.17 001317245.1_07124001_3 - 2.7e-106 355.3 0.0 3.6e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.17 001317245.1_07124001_3 - 1.5e-05 24.0 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V HSP70 PF00012.18 001317272.1_52925001_3 - 1.1e-260 865.9 7.9 1.2e-260 865.7 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001317272.1_52925001_3 - 1.5e-14 53.4 0.4 1.9e-13 49.8 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.14 001317272.1_52925001_3 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.16 001317272.1_52925001_3 - 0.05 12.7 0.4 0.22 10.6 0.1 2.2 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase DDR PF08841.8 001317272.1_52925001_3 - 0.061 12.2 0.4 0.43 9.4 0.2 2.2 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Aminotran_1_2 PF00155.19 001317276.1_52924001_2 - 3.6e-101 338.8 0.0 4.2e-101 338.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ku_N PF03731.13 001317277.1_52924001_3 - 1.7e-55 188.0 0.9 2.7e-55 187.4 0.9 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.14 001317277.1_52924001_3 - 4.8e-40 137.3 0.0 2.1e-39 135.2 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.12 001317277.1_52924001_3 - 7.7e-18 64.9 0.0 2.2e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.25 001317277.1_52924001_3 - 1.2e-06 28.0 1.8 2e-06 27.3 0.0 2.4 3 0 0 3 3 3 1 SAP domain 2OG-FeII_Oxy PF03171.18 001317289.1_52923001_3 - 9.9e-27 93.3 0.0 1.7e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001317289.1_52923001_3 - 1.3e-13 51.6 0.1 2.3e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_1 PF00561.18 001317291.1_52922001_1 - 6.5e-21 75.0 0.1 7.3e-21 74.8 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001317291.1_52922001_1 - 1.1e-16 62.0 0.0 1.6e-16 61.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001317291.1_52922001_1 - 6.5e-09 35.3 0.0 2.2e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.9 001317291.1_52922001_1 - 0.0022 16.9 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.5 001317291.1_52922001_1 - 0.0023 16.7 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Glyco_transf_5 PF08323.9 001317304.1_52926001_1 - 1.1e-66 224.9 0.0 1.6e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 001317304.1_52926001_1 - 5.9e-16 58.4 0.0 1.6e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001317304.1_52926001_1 - 1.9e-15 57.3 0.0 3.7e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001317304.1_52926001_1 - 3.7e-06 26.9 0.1 0.0021 17.9 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.4 001317304.1_52926001_1 - 0.00012 22.4 0.1 0.012 15.9 0.1 2.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Gln-synt_C PF00120.22 001317307.1_52923001_1 - 1.6e-15 56.9 0.0 6.5e-14 51.6 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001317307.1_52923001_1 - 1.7e-10 40.3 0.0 3.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Mitoc_L55 PF09776.7 001317307.1_52923001_1 - 0.041 13.5 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Asparaginase_2 PF01112.16 001317311.1_52923001_3 - 7.5e-51 172.8 5.1 1.1e-50 172.3 5.1 1.2 1 0 0 1 1 1 1 Asparaginase Glyco_transf_5 PF08323.9 001317313.1_52924001_1 - 1.9e-70 237.2 0.0 2.7e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 001317313.1_52924001_1 - 3.2e-16 59.3 0.0 6.3e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001317313.1_52924001_1 - 1.3e-13 51.5 0.2 2.3e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Na_Ca_ex PF01699.22 001317320.1_52924001_1 - 1.1e-41 142.2 36.3 3.9e-22 78.7 11.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Alpha-amylase_C PF02806.16 001317322.1_52926001_1 - 1.4e-25 89.4 0.2 1.1e-24 86.5 0.1 2.6 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.16 001317322.1_52926001_1 - 3.5e-19 68.8 0.0 8.5e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.22 001317322.1_52926001_1 - 2.5e-14 53.5 0.9 5.8e-12 45.7 0.9 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.4 001317322.1_52926001_1 - 0.022 13.7 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Na_H_Exchanger PF00999.19 001317328.1_52925001_1 - 7.7e-59 199.2 36.0 9.9e-59 198.9 36.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FeoB_C PF07664.10 001317328.1_52925001_1 - 0.27 10.8 4.2 12 5.5 0.0 3.7 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus DUF2964 PF11177.6 001317328.1_52925001_1 - 0.32 11.1 4.9 0.2 11.8 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) GSHPx PF00255.17 001317420.1_43622001_1 - 5e-42 141.7 0.2 6.9e-42 141.3 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 001317420.1_43622001_1 - 1.5e-09 37.7 0.2 8e-09 35.3 0.2 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001317420.1_43622001_1 - 2e-07 30.6 0.1 2.2e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.12 001317420.1_43622001_1 - 0.00052 19.8 0.1 0.09 12.5 0.0 2.2 2 0 0 2 2 2 2 SCO1/SenC Peptidase_M85 PF13678.4 001317420.1_43622001_1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease Sod_Fe_C PF02777.16 001302847.1_34422001_1 - 2e-35 120.9 1.0 2.3e-35 120.7 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.20 001302847.1_34422001_1 - 6.3e-35 119.4 0.9 1.3e-34 118.4 0.9 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Glutaredoxin PF00462.22 001288079.1_48622001_3 - 3.3e-11 43.1 0.0 4.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Glyco_transf_5 PF08323.9 001302856.1_34425001_3 - 4.5e-75 252.4 0.0 6.5e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 001302856.1_34425001_3 - 1.4e-12 47.4 0.0 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001302856.1_34425001_3 - 8.8e-10 39.0 0.0 1.5e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001302856.1_34425001_3 - 0.0012 18.8 0.0 0.06 13.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 MFS_2 PF13347.4 001288921.1_12724001_3 - 3e-16 58.9 6.7 3e-16 58.9 6.7 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein PsbW PF07123.10 001288921.1_12724001_3 - 0.11 12.4 3.2 0.21 11.4 0.2 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) RPE65 PF03055.13 001319332.1_35124001_1 - 1.8e-120 402.8 0.0 2.1e-120 402.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GSHPx PF00255.17 001319793.1_43622001_1 - 5.5e-43 144.8 0.1 7.5e-43 144.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.8 001319793.1_43622001_1 - 1.6e-08 34.2 0.1 3.3e-07 29.9 0.1 2.2 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.19 001319793.1_43622001_1 - 3.2e-08 33.4 0.2 1.6e-07 31.1 0.2 2.0 1 1 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.12 001319793.1_43622001_1 - 0.00045 20.0 0.0 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 SCO1/SenC Pkinase PF00069.23 001319695.1_34423001_1 - 6.6e-73 245.2 0.0 8.6e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001319695.1_34423001_1 - 2.2e-34 118.8 0.0 4.1e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001319695.1_34423001_1 - 1.2e-23 82.9 0.6 2.5e-23 81.9 0.6 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001319695.1_34423001_1 - 1.1e-09 37.9 0.0 1.9e-08 33.8 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001319695.1_34423001_1 - 0.0023 17.2 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001319695.1_34423001_1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001319695.1_34423001_1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Spermine_synth PF01564.15 001319815.1_45323001_1 - 1e-85 286.5 0.0 1.3e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_25 PF13649.4 001319815.1_45323001_1 - 6.7e-07 29.8 0.0 1.3e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 001319815.1_45323001_1 - 0.0036 17.8 0.0 0.0073 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.12 001319815.1_45323001_1 - 0.0066 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.4 001319815.1_45323001_1 - 0.019 15.9 0.0 0.039 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.9 001319815.1_45323001_1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.10 001319815.1_45323001_1 - 0.073 13.7 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Myb_DNA-binding PF00249.29 001319857.1_35322001_1 - 2.1e-32 110.9 2.6 5e-16 58.5 2.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001319857.1_35322001_1 - 4.6e-20 71.5 0.6 3.2e-10 40.0 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001319857.1_35322001_1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 SLIDE RPE65 PF03055.13 001319856.1_35324001_1 - 7.8e-122 407.3 0.0 8.9e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPR_2 PF13041.4 001319860.1_35324001_1 - 9.4e-146 473.8 30.8 7.4e-19 67.6 0.0 14.0 2 2 12 14 14 14 14 PPR repeat family PPR_1 PF12854.5 001319860.1_35324001_1 - 6.4e-126 409.6 24.2 5.3e-13 48.3 0.1 14.4 14 0 0 14 14 14 12 PPR repeat PPR PF01535.18 001319860.1_35324001_1 - 3.7e-95 305.7 32.6 1.7e-08 34.0 0.0 15.1 15 0 0 15 15 15 12 PPR repeat PPR_3 PF13812.4 001319860.1_35324001_1 - 8.5e-57 189.0 10.9 1.1e-10 41.3 0.0 8.2 4 1 6 10 10 10 10 Pentatricopeptide repeat domain PPR_long PF17177.2 001319860.1_35324001_1 - 1.1e-26 93.4 0.0 2.8e-08 33.3 0.0 5.0 1 1 4 5 5 5 4 Pentacotripeptide-repeat region of PROPR MRP-S27 PF10037.7 001319860.1_35324001_1 - 4.4e-07 29.0 0.0 0.014 14.2 0.0 3.7 1 1 3 4 4 4 2 Mitochondrial 28S ribosomal protein S27 SPOB_a PF14689.4 001319860.1_35324001_1 - 0.00012 21.6 0.1 7.1 6.3 0.0 5.5 8 0 0 8 8 8 2 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_2 PF07719.15 001319860.1_35324001_1 - 0.00021 21.0 0.2 77 3.6 0.0 6.8 9 0 0 9 9 8 0 Tetratricopeptide repeat ATP13 PF12921.5 001319860.1_35324001_1 - 0.00026 20.7 0.0 27 4.5 0.0 5.7 2 1 3 5 5 5 0 Mitochondrial ATPase expression ECSIT PF06239.9 001319860.1_35324001_1 - 0.00049 19.1 0.4 8.9 5.2 0.1 4.7 3 1 1 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_6 PF13174.4 001319860.1_35324001_1 - 0.047 14.2 0.3 1e+02 3.8 0.0 5.2 6 1 0 6 6 5 0 Tetratricopeptide repeat Clathrin PF00637.18 001319860.1_35324001_1 - 0.052 13.3 0.0 61 3.3 0.0 4.3 3 2 1 4 4 4 0 Region in Clathrin and VPS RTP1_C1 PF10363.7 001319860.1_35324001_1 - 0.1 12.6 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 zn-ribbon_14 PF16503.3 001319860.1_35324001_2 - 0.051 12.9 0.7 0.11 11.9 0.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon 2OG-FeII_Oxy PF03171.18 001319285.1_08323001_1 - 2.2e-28 98.5 0.0 3.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001319285.1_08323001_1 - 9.4e-19 68.2 0.0 1.6e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pkinase PF00069.23 001319694.1_34423001_1 - 4.8e-75 252.2 0.0 6.3e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001319694.1_34423001_1 - 2.9e-39 134.8 0.0 3.9e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001319694.1_34423001_1 - 3.5e-21 75.0 1.7 9.5e-21 73.6 1.7 1.7 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001319694.1_34423001_1 - 3.8e-12 46.0 0.0 4e-11 42.6 0.0 2.3 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.12 001319694.1_34423001_1 - 0.0011 18.3 0.3 0.0054 16.0 0.0 2.2 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001319694.1_34423001_1 - 0.0035 17.2 0.0 0.15 11.8 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_1 PF00036.30 001319335.1_35122001_1 - 3.8e-18 63.5 11.7 1.9e-05 23.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001319335.1_35122001_1 - 2.1e-15 55.1 10.6 0.00037 20.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001319335.1_35122001_1 - 5.2e-14 50.9 10.9 5.3e-07 28.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001319335.1_35122001_1 - 4e-12 46.3 10.4 4.4e-09 36.6 1.5 3.5 2 2 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.4 001319335.1_35122001_1 - 1.7e-06 27.6 10.3 0.0067 16.0 0.8 4.0 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.5 001319335.1_35122001_1 - 0.001 18.8 3.8 0.018 14.8 0.2 2.6 1 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001319335.1_35122001_1 - 0.008 16.3 0.3 1.2 9.4 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.7 001319335.1_35122001_1 - 0.025 14.8 2.4 0.087 13.0 1.2 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.23 001319693.1_34423001_1 - 7.9e-72 241.6 0.0 1e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001319693.1_34423001_1 - 4.3e-38 131.0 0.0 6.3e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001319693.1_34423001_1 - 1.1e-19 70.2 0.7 2.2e-19 69.3 0.7 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001319693.1_34423001_1 - 7.8e-10 38.4 0.0 3.5e-08 33.0 0.0 2.7 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.12 001319693.1_34423001_1 - 0.025 13.8 0.1 0.32 10.2 0.0 2.4 2 1 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_31 PF13847.4 001319693.1_34423001_1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain APH PF01636.21 001319693.1_34423001_1 - 0.21 11.3 0.4 0.78 9.5 0.6 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family AP2 PF00847.18 001320065.1_12722001_1 - 7.5e-14 51.6 0.8 1.4e-13 50.7 0.8 1.5 1 0 0 1 1 1 1 AP2 domain CAML PF14963.4 001320065.1_12722001_1 - 0.06 13.3 0.5 0.06 13.3 0.5 1.9 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF1754 PF08555.8 001320065.1_12722001_1 - 0.88 10.3 12.7 0.29 11.8 3.4 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) SRF-TF PF00319.16 001320066.1_12723001_3 - 2.3e-26 90.9 0.3 4.4e-26 90.0 0.3 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001320066.1_12723001_3 - 1.8e-23 82.4 14.3 1.8e-23 82.4 14.3 1.8 2 0 0 2 2 2 1 K-box region ZapB PF06005.10 001320066.1_12723001_3 - 4.4 7.7 14.5 0.39 11.1 2.9 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Peptidase_C1 PF00112.21 001320061.1_12723001_1 - 2.7e-84 282.5 1.8 2.7e-84 282.5 1.8 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001320061.1_12723001_1 - 7.9e-13 48.5 5.7 1.4e-12 47.7 5.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 001320061.1_12723001_1 - 0.0016 17.1 5.4 0.027 13.1 0.2 2.7 3 0 0 3 3 3 2 Peptidase C1-like family EF-hand_6 PF13405.4 001320068.1_12722001_3 - 1e-22 78.0 3.9 1.7e-08 33.6 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.30 001320068.1_12722001_3 - 1.5e-22 77.3 7.8 6.4e-07 28.3 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.4 001320068.1_12722001_3 - 9.3e-20 69.1 3.5 2.6e-06 26.5 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.4 001320068.1_12722001_3 - 2.3e-18 66.3 2.7 8.8e-11 42.0 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001320068.1_12722001_3 - 1.4e-10 40.6 8.6 1.8e-06 27.5 0.3 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.4 001320068.1_12722001_3 - 3.3e-05 24.0 0.0 0.25 11.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.11 001320068.1_12722001_3 - 0.00077 19.3 0.2 0.12 12.1 0.0 2.7 2 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.7 001320068.1_12722001_3 - 0.0084 16.3 0.1 0.31 11.2 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Glyco_hydro_100 PF12899.5 126790.1_24121120_2 - 7e-05 21.5 0.1 8.9e-05 21.2 0.1 1.1 1 0 0 1 1 1 1 Alkaline and neutral invertase Comm PF15957.3 126811.1_24121120_3 - 0.6 10.3 3.6 0.77 10.0 3.6 1.2 1 0 0 1 1 1 0 Commissureless zf-piccolo PF05715.11 048629.1_24121120_2 - 0.015 15.3 0.8 0.04 13.9 0.9 1.7 2 0 0 2 2 2 0 Piccolo Zn-finger NB-ARC PF00931.20 048629.1_24121120_3 - 0.00014 20.8 0.0 0.00016 20.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain Glyoxalase_4 PF13669.4 001323439.1_48523001_1 - 4.8e-08 33.1 0.0 0.016 15.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.23 001323439.1_48523001_1 - 1e-07 32.0 0.0 1.7e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.4 001323439.1_48523001_1 - 0.00015 21.8 0.1 0.00096 19.2 0.0 2.3 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Methyltransf_11 PF08241.10 001323468.1_48523001_1 - 6.9e-19 68.1 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001323468.1_48523001_1 - 4.9e-18 65.5 0.0 7.9e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.16 001323468.1_48523001_1 - 5.2e-16 58.5 0.0 6.8e-14 51.6 0.0 2.1 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.4 001323468.1_48523001_1 - 4.6e-12 45.9 0.0 6.1e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001323468.1_48523001_1 - 2e-11 44.3 0.0 3.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 001323468.1_48523001_1 - 7.6e-10 38.8 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.16 001323468.1_48523001_1 - 0.00014 21.0 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.18 001323468.1_48523001_1 - 0.00037 19.5 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.13 001323468.1_48523001_1 - 0.0072 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.12 001323468.1_48523001_1 - 0.014 14.8 0.0 0.073 12.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_9 PF08003.9 001323468.1_48523001_1 - 0.067 12.0 0.0 9.4 4.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Transferase PF02458.13 001323455.1_48523001_1 - 1.1e-76 258.1 0.0 1.5e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Transferase family Methyltransf_11 PF08241.10 001323452.1_48523001_1 - 4.5e-21 75.1 0.0 8.1e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001323452.1_48523001_1 - 6.6e-19 68.3 0.0 1.3e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 001323452.1_48523001_1 - 3.1e-15 56.3 0.0 4.6e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001323452.1_48523001_1 - 2.4e-14 53.3 0.0 3.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.18 001323452.1_48523001_1 - 6.2e-13 48.5 0.0 8.5e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.10 001323452.1_48523001_1 - 9.5e-09 35.8 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.16 001323452.1_48523001_1 - 8.1e-06 25.2 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NAS PF03059.14 001323452.1_48523001_1 - 0.011 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein MetW PF07021.10 001323452.1_48523001_1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.4 001323452.1_48523001_1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.16 001323452.1_48523001_1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.12 001323452.1_48523001_1 - 0.033 13.6 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CCAP PF11105.6 001323452.1_48523001_1 - 0.058 13.2 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a Methyltransf_20 PF12147.6 001323452.1_48523001_1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase N2227 PF07942.10 001323452.1_48523001_1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Filament_head PF04732.12 001323452.1_48523001_1 - 0.76 10.6 5.0 0.86 10.4 0.0 2.8 2 1 0 2 2 2 0 Intermediate filament head (DNA binding) region Aminotran_1_2 PF00155.19 001323447.1_48523001_1 - 6.6e-50 170.2 0.0 7.4e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001323447.1_48523001_1 - 4.7e-07 29.2 0.0 6.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.17 001323447.1_48523001_1 - 0.0026 16.6 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.19 001323447.1_48523001_1 - 0.0029 16.2 0.0 0.0043 15.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.23 001323430.1_48527001_1 - 8.2e-46 156.4 0.0 1.2e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001323430.1_48527001_1 - 7.8e-45 153.0 0.0 1.1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.4 001323430.1_48527001_1 - 5.7e-33 112.3 44.6 6.2e-08 32.1 4.2 9.6 4 3 5 10 10 10 8 Leucine rich repeat LRR_4 PF12799.5 001323430.1_48527001_1 - 9.3e-33 111.5 49.3 4.2e-06 26.8 0.1 12.4 5 3 7 14 14 14 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001323430.1_48527001_1 - 1.7e-15 54.9 30.1 0.21 12.1 0.0 15.2 15 2 0 15 15 15 3 Leucine Rich Repeat LRRNT_2 PF08263.10 001323430.1_48527001_1 - 5.6e-12 45.6 0.4 1.1e-11 44.6 0.4 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.4 001323430.1_48527001_1 - 2.3e-11 42.6 23.0 0.21 11.6 0.5 12.4 12 0 0 12 12 12 3 Leucine Rich repeat LRR_2 PF07723.11 001323430.1_48527001_1 - 0.0012 19.3 0.1 9.5 7.0 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich Repeat APH PF01636.21 001323430.1_48527001_1 - 0.18 11.6 0.1 0.32 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_9 PF14580.4 001323430.1_48527001_1 - 0.22 10.9 5.0 2 7.8 0.1 3.6 4 0 0 4 4 4 0 Leucine-rich repeat F-box PF00646.31 001323469.1_48523001_1 - 7.9e-08 31.9 1.0 1.7e-07 30.8 1.0 1.5 1 0 0 1 1 1 1 F-box domain FBA_1 PF07734.11 001323469.1_48523001_1 - 3.8e-05 23.5 0.0 6.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 F-box associated F-box-like PF12937.5 001323469.1_48523001_1 - 0.00013 21.6 0.5 0.0003 20.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like FBA_3 PF08268.10 001323469.1_48523001_1 - 0.0064 16.3 0.1 0.044 13.6 0.1 2.1 2 0 0 2 2 2 1 F-box associated domain polyprenyl_synt PF00348.15 001323466.1_48523001_1 - 6.5e-34 117.0 0.0 9e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase FBA_1 PF07734.11 001323464.1_48523001_1 - 3.3e-08 33.5 0.1 5.9e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 F-box associated F-box PF00646.31 001323464.1_48523001_1 - 0.0003 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain Kelch_1 PF01344.23 001323464.1_48523001_1 - 0.003 17.0 0.1 1.4 8.4 0.0 3.0 3 0 0 3 3 3 2 Kelch motif FBA_3 PF08268.10 001323464.1_48523001_1 - 0.033 14.0 2.9 0.045 13.6 0.5 2.3 2 1 1 3 3 3 0 F-box associated domain hSac2 PF12456.6 001323464.1_48523001_1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Inositol phosphatase HMGL-like PF00682.17 001323449.1_48523001_1 - 5.1e-91 304.8 2.4 6.1e-91 304.5 2.4 1.1 1 0 0 1 1 1 1 HMGL-like AP_endonuc_2 PF01261.22 001323449.1_48523001_1 - 0.082 12.2 0.0 0.26 10.5 0.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel FBA_1 PF07734.11 001323461.1_48523001_1 - 4e-06 26.7 0.0 6.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 F-box associated FBA_3 PF08268.10 001323461.1_48523001_1 - 0.00033 20.4 0.1 0.002 17.9 0.0 2.1 2 0 0 2 2 2 1 F-box associated domain F-box PF00646.31 001323461.1_48523001_1 - 0.0089 15.8 0.1 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain Tocopherol_cycl PF14249.4 001323450.1_48523001_1 - 1.1e-146 488.2 7.0 1.4e-146 487.9 7.0 1.1 1 0 0 1 1 1 1 Tocopherol cyclase CIA30 PF08547.10 001323450.1_48523001_1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) HMGL-like PF00682.17 001323473.1_48523001_1 - 2.7e-91 305.6 2.5 3.2e-91 305.4 2.5 1.1 1 0 0 1 1 1 1 HMGL-like AP_endonuc_2 PF01261.22 001323473.1_48523001_1 - 0.065 12.5 0.0 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel FBA_1 PF07734.11 001323465.1_48523001_1 - 9.7e-08 32.0 0.6 2e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 F-box associated FBA_3 PF08268.10 001323465.1_48523001_1 - 2.1e-05 24.3 0.7 4.2e-05 23.4 0.2 1.8 2 0 0 2 2 2 1 F-box associated domain F-box PF00646.31 001323465.1_48523001_1 - 0.0049 16.6 0.4 0.014 15.2 0.4 1.7 1 0 0 1 1 1 1 F-box domain CRAL_TRIO PF00650.18 001323470.1_48523001_1 - 5.7e-33 113.8 0.1 8.6e-33 113.2 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.13 001323470.1_48523001_1 - 1.1e-12 47.8 0.7 3e-11 43.2 0.0 2.8 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain UbiA PF01040.16 001323445.1_48523001_1 - 1.9e-41 141.9 27.0 2.4e-41 141.6 27.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family SPC12 PF06645.11 001323445.1_48523001_1 - 9.6 6.2 13.3 3.5 7.7 0.5 3.1 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Cullin PF00888.20 001323441.1_48526001_3 - 4.3e-172 573.8 19.8 6.2e-172 573.2 19.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.7 001323441.1_48526001_3 - 4.7e-26 90.5 3.1 1.2e-25 89.2 3.1 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain SF3a60_bindingd PF12108.6 001323441.1_48526001_3 - 0.11 12.2 0.6 2.9 7.7 0.1 2.6 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain F-box PF00646.31 001323453.1_48523001_1 - 0.0045 16.7 1.2 0.015 15.0 1.2 1.9 1 0 0 1 1 1 1 F-box domain FBA_1 PF07734.11 001323453.1_48523001_1 - 0.0069 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 F-box associated FBA_3 PF08268.10 001323453.1_48523001_1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 F-box associated domain Peptidase_S10 PF00450.20 001323472.1_48524001_1 - 2.4e-125 419.1 0.2 2.7e-125 418.9 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Tubulin PF00091.23 001323889.1_53923001_1 - 1.3e-67 227.7 0.0 1.7e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001323889.1_53923001_1 - 2.7e-50 169.7 0.0 4.1e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001323889.1_53923001_1 - 0.0083 15.7 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain EF1G PF00647.17 001323859.1_53923001_1 - 1.4e-42 143.9 1.2 9.2e-42 141.3 0.0 2.6 3 0 0 3 3 3 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.18 001323859.1_53923001_1 - 3.5e-16 59.2 0.0 8.6e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001323859.1_53923001_1 - 4.4e-09 36.3 0.0 1.3e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001323859.1_53923001_1 - 4.3e-08 33.3 0.0 8.7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001323859.1_53923001_1 - 1.6e-06 28.2 0.0 3.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001323859.1_53923001_1 - 2.7e-05 24.2 0.0 6.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001323859.1_53923001_1 - 2.9e-05 23.8 0.1 9.8e-05 22.1 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain HABP4_PAI-RBP1 PF04774.13 001323859.1_53923001_1 - 0.02 15.6 4.5 0.02 15.6 4.5 1.9 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Mitofilin PF09731.7 001323859.1_53923001_1 - 4.8 5.7 7.1 6.7 5.3 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GTP_EFTU PF00009.25 001323875.1_53923001_1 - 1.2e-53 181.4 0.1 3e-53 180.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001323875.1_53923001_1 - 2.7e-38 130.6 0.0 6.2e-38 129.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001323875.1_53923001_1 - 1.3e-14 54.2 3.0 3.1e-14 53.0 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001323875.1_53923001_1 - 0.00087 19.2 0.2 0.0036 17.2 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001323875.1_53923001_1 - 0.0072 16.2 0.1 0.0072 16.2 0.1 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 4 SRPRB PF09439.8 001323875.1_53923001_1 - 0.011 15.0 0.1 0.2 10.9 0.1 2.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FlpD PF02662.14 001323875.1_53923001_1 - 0.019 14.9 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.16 001323875.1_53923001_1 - 0.034 14.1 0.1 0.099 12.6 0.0 1.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain AAA_22 PF13401.4 001323875.1_53923001_1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NIR_SIR PF01077.20 001323860.1_53924001_1 - 2.8e-62 208.8 0.0 8.5e-50 168.2 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.15 001323860.1_53924001_1 - 2.5e-13 49.5 0.0 2.7e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain DUF3126 PF11324.6 001323860.1_53924001_1 - 0.17 11.6 0.3 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3126) Chloroa_b-bind PF00504.19 001323867.1_53922001_3 - 2.5e-50 171.0 0.1 4.3e-50 170.2 0.0 1.4 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Actin PF00022.17 001323878.1_53923001_1 - 1.2e-147 491.7 0.0 3.7e-147 490.0 0.0 1.6 1 1 0 1 1 1 1 Actin GnRH PF00446.15 001323878.1_53923001_3 - 8.6 6.9 9.0 7 7.2 1.2 3.2 2 0 0 2 2 2 0 Gonadotropin-releasing hormone Glyoxal_oxid_N PF07250.9 001323872.1_53924001_1 - 5.4e-113 376.0 0.0 1.2e-110 368.2 0.0 2.5 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.9 001323872.1_53924001_1 - 3.1e-26 91.4 1.0 5.8e-26 90.5 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.4 001323872.1_53924001_1 - 5.5e-05 22.9 3.3 7.6 6.5 0.1 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain ACP_syn_III_C PF08541.8 001323753.1_46323001_1 - 9.1e-39 131.4 0.2 3.7e-38 129.4 0.1 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.8 001323753.1_46323001_1 - 3.8e-29 100.2 3.8 9.4e-28 95.8 2.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.21 001323753.1_46323001_1 - 1.9e-05 24.0 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Chal_sti_synt_C PF02797.13 001323753.1_46323001_1 - 9.6e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Ketoacyl-synt_C PF02801.20 001323753.1_46323001_1 - 0.0038 17.1 0.4 1.6 8.6 0.0 3.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.9 001323753.1_46323001_1 - 0.036 12.6 0.0 0.48 8.9 0.0 2.1 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) FA_desaturase_2 PF03405.12 001323745.1_46323001_1 - 2.4e-154 512.9 0.0 2.8e-154 512.7 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.15 001323745.1_46323001_1 - 0.00019 21.7 0.0 0.29 11.4 0.0 2.8 3 0 0 3 3 3 2 Rubrerythrin ELP6 PF09807.7 001323745.1_46323001_1 - 0.21 10.8 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Elongation complex protein 6 MIP PF00230.18 001323864.1_53922001_1 - 4.2e-81 271.8 12.8 4.8e-81 271.6 12.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_17 PF00332.16 001323887.1_53924001_2 - 3.3e-98 328.8 0.7 4e-98 328.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001323887.1_53924001_2 - 5.4e-23 81.3 1.5 1.2e-22 80.2 1.5 1.6 1 0 0 1 1 1 1 X8 domain Pollen_allerg_1 PF01357.19 001323882.1_53922001_3 - 5.3e-19 67.9 0.4 8.4e-19 67.3 0.4 1.3 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001323882.1_53922001_3 - 2.7e-12 46.7 0.3 1e-11 44.8 0.1 2.1 3 0 0 3 3 3 1 Lytic transglycolase Pollen_allerg_1 PF01357.19 001323858.1_53923001_1 - 8.9e-29 99.2 0.7 1.5e-28 98.5 0.7 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001323858.1_53923001_1 - 6.4e-23 80.7 1.4 9.9e-23 80.1 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.19 001323865.1_53922001_1 - 9.8e-30 102.3 1.2 1.8e-29 101.5 1.2 1.5 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001323865.1_53922001_1 - 5.8e-22 77.6 0.9 1.4e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 Lytic transglycolase NTP_transferase PF00483.21 001323861.1_53923001_1 - 2.2e-52 178.0 0.0 3.2e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001323861.1_53923001_1 - 2.6e-10 40.7 0.0 3.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001323861.1_53923001_1 - 5.7e-08 32.0 10.0 1.4e-07 30.8 0.9 3.7 2 1 3 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.4 001323861.1_53923001_1 - 0.0015 18.1 4.1 0.017 14.8 3.1 3.3 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.3 001323861.1_53923001_1 - 0.012 13.6 0.2 0.018 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) DUF257 PF03192.11 001323861.1_53923001_1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 CTP_transf_3 PF02348.17 001323861.1_53923001_1 - 0.024 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.10 001323861.1_53923001_1 - 0.046 12.6 0.0 0.92 8.3 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase IspD PF01128.17 001323861.1_53923001_1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Catalase PF00199.17 001323871.1_53924001_2 - 1.6e-172 573.8 0.0 1.8e-172 573.6 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.10 001323871.1_53924001_2 - 2.3e-17 62.8 0.0 7.4e-17 61.2 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Lycopene_cycl PF05834.10 001323443.1_48523001_1 - 2.2e-153 510.7 0.0 2.6e-153 510.5 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.12 001323443.1_48523001_1 - 1.8e-07 30.6 0.0 5.2e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001323443.1_48523001_1 - 6.4e-06 25.5 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.15 001323443.1_48523001_1 - 3.5e-05 23.0 0.0 0.0014 17.8 0.0 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.12 001323443.1_48523001_1 - 0.00017 20.3 0.0 0.00061 18.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.22 001323443.1_48523001_1 - 0.00029 19.9 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.12 001323443.1_48523001_1 - 0.00037 19.3 0.1 0.0088 14.8 0.0 2.3 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.4 001323443.1_48523001_1 - 0.0012 18.0 0.0 0.0089 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001323443.1_48523001_1 - 0.0035 16.9 0.0 2.2 7.7 0.1 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.4 001323443.1_48523001_1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.25 001323443.1_48523001_1 - 0.021 15.3 0.1 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001323443.1_48523001_1 - 0.027 13.4 0.0 0.057 12.4 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.4 001323443.1_48523001_1 - 0.03 14.2 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.16 001323443.1_48523001_1 - 0.091 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Metallothio_Cad PF07846.9 001323443.1_48523001_1 - 0.1 12.6 1.1 14 5.7 0.6 2.8 2 0 0 2 2 2 0 Metallothionein family 2-Hacid_dh_C PF02826.17 001323443.1_48523001_1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.4 001323443.1_48523001_1 - 0.14 12.5 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain 2OG-FeII_Oxy PF03171.18 001323866.1_53923001_3 - 5e-27 94.2 0.0 1.2e-26 93.0 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001323866.1_53923001_3 - 1.6e-14 54.5 0.1 4.6e-14 53.1 0.1 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Terpene_synth_C PF03936.14 001323454.1_48525001_1 - 8.7e-58 195.7 5.8 1.8e-57 194.6 5.8 1.6 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001323454.1_48525001_1 - 1.9e-43 148.3 5.4 3.6e-43 147.3 5.4 1.5 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain Prenyltrans PF00432.19 001323454.1_48525001_1 - 0.0012 18.4 0.0 0.0048 16.5 0.1 2.0 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat Leuk-A4-hydro_C PF09127.9 001323454.1_48525001_1 - 0.0062 16.4 0.5 0.76 9.6 0.2 2.9 1 1 1 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Response_reg PF00072.22 001323876.1_53926001_2 - 3.2e-19 69.0 0.0 7.9e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.24 001323876.1_53926001_2 - 4.7e-11 43.1 0.1 1.1e-10 42.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.24 001323876.1_53926001_2 - 3.8e-10 40.3 0.0 1.1e-09 38.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.23 001323876.1_53926001_2 - 2.7e-07 30.4 0.1 7.7e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.4 001323876.1_53926001_2 - 0.073 13.3 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 GAF domain 2OG-FeII_Oxy PF03171.18 001323868.1_53923001_3 - 2.1e-28 98.6 0.0 4.7e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001323868.1_53923001_3 - 1.4e-14 54.7 0.0 2.9e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HATPase_c PF02518.24 001323874.1_53925001_1 - 2.4e-31 108.4 0.0 5e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.23 001323874.1_53925001_1 - 3.1e-15 55.8 2.6 3.1e-15 55.8 2.6 3.1 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain GAF PF01590.24 001323874.1_53925001_1 - 5.8e-14 52.6 0.4 7e-13 49.1 0.1 2.4 2 0 0 2 2 2 1 GAF domain Response_reg PF00072.22 001323874.1_53925001_1 - 3.8e-08 33.4 0.0 9.9e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain GAF_3 PF13492.4 001323874.1_53925001_1 - 0.011 16.0 0.1 6.9 6.9 0.0 2.7 2 0 0 2 2 2 0 GAF domain Pkinase PF00069.23 001288871.1_12724001_1 - 1.2e-44 152.5 0.0 1.6e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288871.1_12724001_1 - 4.8e-43 147.2 0.0 6.1e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRRNT_2 PF08263.10 001288871.1_12724001_1 - 6.3e-11 42.2 1.0 1.8e-10 40.8 1.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001288871.1_12724001_1 - 5.3e-09 36.0 14.5 0.00039 20.6 1.9 3.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001288871.1_12724001_1 - 8.1e-09 35.0 13.7 0.0018 17.8 4.6 2.9 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.31 001288871.1_12724001_1 - 1.8e-05 24.4 10.7 0.78 10.3 0.1 5.2 4 0 0 4 4 4 3 Leucine Rich Repeat APH PF01636.21 001288871.1_12724001_1 - 0.00027 20.8 0.1 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.14 001288871.1_12724001_1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.4 001288871.1_12724001_1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SKG6 PF08693.8 001288871.1_12724001_1 - 0.21 10.9 0.4 0.35 10.2 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_6 PF13516.4 001288871.1_12724001_1 - 1.7 8.8 9.4 7.3 6.8 0.3 4.5 4 0 0 4 4 4 0 Leucine Rich repeat K-box PF01486.15 001288843.1_12723001_3 - 2.6e-26 91.5 14.1 5.2e-26 90.5 14.1 1.6 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001288843.1_12723001_3 - 4.2e-26 90.0 0.2 8.4e-26 89.1 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PfkB PF00294.22 001288843.1_12723001_3 - 0.12 11.6 0.4 0.16 11.1 0.4 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase DUF4446 PF14584.4 001288843.1_12723001_3 - 0.14 12.0 5.1 0.24 11.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) ATP-synt_G PF04718.13 001288843.1_12723001_3 - 0.34 11.6 2.6 1.8 9.3 0.2 2.6 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit Phospholip_A2_1 PF00068.17 001288940.1_12722001_1 - 0.00036 20.8 15.4 0.0013 19.0 15.4 1.9 1 1 1 2 2 2 1 Phospholipase A2 Maf1 PF09174.8 001288845.1_12724001_1 - 4.3e-46 156.8 2.1 5.7e-46 156.4 2.1 1.2 1 0 0 1 1 1 1 Maf1 regulator 2OG-FeII_Oxy PF03171.18 001288883.1_12723001_3 - 3.7e-28 97.8 0.0 8.9e-28 96.6 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001288883.1_12723001_3 - 1.1e-13 51.9 0.0 2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Octopine_DH PF02317.15 001288883.1_12723001_3 - 0.00019 21.4 0.1 0.26 11.2 0.0 2.3 1 1 1 2 2 2 2 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain p450 PF00067.20 001288907.1_12724001_3 - 7.8e-74 248.9 0.0 1.1e-73 248.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_28 PF00295.15 001288908.1_12724001_2 - 2.6e-95 319.1 4.5 3.3e-95 318.8 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.5 001288908.1_12724001_2 - 2.1e-05 24.4 9.2 0.00046 20.0 8.5 3.3 1 1 0 1 1 1 1 Pectate lyase superfamily protein NosD PF05048.11 001288908.1_12724001_2 - 0.45 9.6 5.2 1.1 8.3 4.7 1.8 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Somatostatin PF03002.13 001288908.1_12724001_3 - 0.45 10.4 3.0 0.75 9.7 3.0 1.3 1 0 0 1 1 1 0 Somatostatin/Cortistatin family DNA_methylase PF00145.15 001288948.1_12726001_1 - 1.5e-40 139.4 0.0 2.8e-35 122.1 0.0 2.6 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Chromo PF00385.22 001288948.1_12726001_1 - 2.2e-10 40.1 0.1 5.3e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BAH PF01426.16 001288948.1_12726001_1 - 3.1e-07 30.1 0.0 2e-06 27.5 0.1 2.2 2 1 0 2 2 2 1 BAH domain Lipocalin_2 PF08212.10 001289143.1_12722001_1 - 8.2e-54 181.3 0.1 9.7e-54 181.1 0.1 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.21 001289143.1_12722001_1 - 4.1e-07 30.2 0.0 5.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family RRM_1 PF00076.20 001288896.1_12726001_1 - 5.5e-42 141.3 4.1 5.3e-17 61.3 0.1 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001288896.1_12726001_1 - 1.2e-07 31.6 0.1 0.14 12.1 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.4 001288896.1_12726001_1 - 1.2e-06 28.3 0.0 0.0019 18.0 0.0 2.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.4 001288896.1_12726001_1 - 1e-05 25.0 0.0 0.0025 17.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.4 001288896.1_12726001_1 - 0.017 15.2 0.8 9.7 6.3 0.0 3.8 2 2 3 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.6 001288896.1_12726001_1 - 0.03 14.3 0.2 8.3 6.4 0.1 3.0 3 0 0 3 3 3 0 Limkain b1 NAM PF02365.13 001288863.1_12723001_2 - 2.2e-27 95.6 0.1 3.6e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein zf-P11 PF03854.12 001288863.1_12723001_2 - 0.1 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 P-11 zinc finger Glyco_hydro_9 PF00759.17 001288865.1_12724001_2 - 8.3e-143 476.6 7.6 9.6e-143 476.4 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 p450 PF00067.20 001288924.1_12724001_3 - 1.5e-20 73.2 0.0 3.6e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Response_reg PF00072.22 001288926.1_12726001_2 - 1.5e-20 73.3 0.0 3.3e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.24 001288926.1_12726001_2 - 9.6e-12 45.5 0.1 3.1e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 GAF domain HATPase_c PF02518.24 001288926.1_12726001_2 - 0.00041 20.8 0.0 0.00089 19.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.23 001288926.1_12726001_2 - 0.00082 19.2 0.0 0.0044 16.9 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DNA_ligase_A_N PF04675.12 001288926.1_12726001_2 - 0.059 13.6 0.3 5.5 7.2 0.0 2.8 3 0 0 3 3 3 0 DNA ligase N terminus Myb_DNA-binding PF00249.29 001287845.1_48623001_1 - 3e-30 104.0 4.1 1.5e-15 56.9 1.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001287845.1_48623001_1 - 5.7e-18 64.8 0.2 3e-09 36.8 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Per1 PF04080.11 001288135.1_48623001_1 - 8.5e-90 300.8 9.9 1.1e-89 300.4 9.9 1.2 1 0 0 1 1 1 1 Per1-like Cofilin_ADF PF00241.18 001288689.1_48622001_1 - 9.1e-36 122.7 0.6 1.3e-35 122.2 0.6 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pkinase_Tyr PF07714.15 001287917.1_48624001_3 - 4.4e-47 160.4 0.0 6.7e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001287917.1_48624001_3 - 4.4e-46 157.2 0.0 7.1e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.4 001287917.1_48624001_3 - 0.092 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.21 001287917.1_48624001_3 - 0.1 12.3 0.1 3.3 7.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family cobW PF02492.17 001287920.1_48622001_1 - 3.7e-32 111.2 0.0 4.7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.14 001287920.1_48622001_1 - 0.00013 21.0 1.1 0.0049 15.8 1.1 2.1 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.21 001287920.1_48622001_1 - 0.058 13.4 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase TIP49 PF06068.11 001287920.1_48622001_1 - 0.064 12.1 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.4 001287920.1_48622001_1 - 0.089 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.13 001287920.1_48622001_1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.27 001287920.1_48622001_1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.30 001288383.1_48623001_3 - 3.5e-25 87.6 15.5 0.00032 21.3 0.6 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001288383.1_48623001_3 - 1.4e-08 34.8 8.9 0.018 15.2 0.2 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Big_2 PF02368.16 001288383.1_48623001_3 - 0.018 14.8 1.0 4.6 7.1 0.4 2.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) IKI3 PF04762.10 001288383.1_48623001_3 - 0.046 11.6 0.5 1.1 7.0 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Ribosomal_L16 PF00252.16 001288167.1_48622001_3 - 1.3e-41 141.6 0.1 1.7e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L18A PF01775.15 001288178.1_48622001_3 - 5.3e-54 181.4 4.5 8.6e-54 180.7 4.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ribosomal_60s PF00428.17 001288190.1_48622001_1 - 4e-07 30.4 2.9 5.8e-07 29.9 2.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.17 001288190.1_48622001_2 - 1e-09 38.7 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein bHLH-MYC_N PF14215.4 001288203.1_48624001_1 - 1.8e-52 178.0 0.0 4.2e-52 176.7 0.0 1.7 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 001288203.1_48624001_1 - 4.4e-11 42.4 1.4 1.3e-10 41.0 1.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_31 PF01055.24 001288463.1_48627001_3 - 7.1e-148 493.3 0.3 1.2e-147 492.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.3 001288463.1_48627001_3 - 2.6e-37 127.4 0.2 5.4e-37 126.4 0.2 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.4 001288463.1_48627001_3 - 2.4e-08 34.0 1.7 4.5e-07 30.0 0.5 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like Shikimate_DH PF01488.18 001323873.1_53924001_1 - 2.3e-46 157.2 0.1 5.9e-46 155.8 0.1 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_N PF05201.13 001323873.1_53924001_1 - 7.9e-39 132.4 0.0 1.7e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain GlutR_dimer PF00745.18 001323873.1_53924001_1 - 2.9e-30 104.4 0.2 6.3e-30 103.3 0.2 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.15 001323873.1_53924001_1 - 2.7e-07 31.0 4.4 3.4e-07 30.6 0.0 3.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.13 001323873.1_53924001_1 - 1.7e-05 25.0 0.5 4.9e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.16 001323873.1_53924001_1 - 1.8e-05 24.9 0.9 7.1e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain OCD_Mu_crystall PF02423.13 001323873.1_53924001_1 - 5.1e-05 22.2 0.3 0.00011 21.1 0.1 1.6 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.16 001323873.1_53924001_1 - 0.00012 22.1 1.8 0.00015 21.8 0.2 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_10 PF13460.4 001323873.1_53924001_1 - 0.00065 19.5 0.2 0.0013 18.5 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Glu_dehyd_C PF16912.3 001323873.1_53924001_1 - 0.0013 18.1 0.2 0.0026 17.1 0.2 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.17 001323873.1_53924001_1 - 0.0021 17.3 0.1 0.006 15.8 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.14 001323873.1_53924001_1 - 0.0034 16.9 0.0 0.0075 15.8 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA KR PF08659.8 001323873.1_53924001_1 - 0.034 13.9 1.2 0.059 13.1 0.0 2.1 2 0 0 2 2 2 0 KR domain GFO_IDH_MocA PF01408.20 001323873.1_53924001_1 - 0.075 13.7 0.3 0.3 11.8 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.4 001323873.1_53924001_1 - 1.1 9.6 9.0 0.094 13.0 1.5 2.9 3 1 1 4 4 3 0 Putative NAD(P)-binding GTP_EFTU PF00009.25 001323857.1_53925001_3 - 7.4e-53 178.9 0.0 1.5e-52 177.8 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001323857.1_53925001_3 - 1.9e-38 131.1 0.0 4e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001323857.1_53925001_3 - 1.4e-14 54.1 0.5 3.6e-14 52.8 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MatE PF01554.16 001323857.1_53925001_3 - 4.7e-09 36.0 6.1 3.9e-05 23.2 0.5 2.5 2 0 0 2 2 2 2 MatE GTP_EFTU_D4 PF14578.4 001323857.1_53925001_3 - 0.0065 16.3 1.6 0.0085 15.9 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.21 001323857.1_53925001_3 - 0.012 15.5 0.1 0.04 13.9 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.8 001323857.1_53925001_3 - 0.052 12.8 0.1 0.51 9.6 0.0 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Polysacc_synt_C PF14667.4 001323857.1_53925001_3 - 0.064 13.2 13.6 0.014 15.3 9.5 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Semialdhyde_dhC PF02774.16 001323857.1_53925001_3 - 0.13 12.2 0.1 0.34 10.8 0.0 1.6 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain DXP_synthase_N PF13292.4 001325159.1_35225001_1 - 1.7e-112 375.0 0.1 2.7e-112 374.3 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.22 001325159.1_35225001_1 - 1.2e-42 145.5 0.1 1.9e-42 144.8 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 001325159.1_35225001_1 - 4e-32 110.6 0.0 8.3e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.18 001325159.1_35225001_1 - 1.2e-06 27.6 0.1 2e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.19 001325159.1_35225001_1 - 9.2e-05 22.1 0.6 0.0011 18.7 0.7 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.19 001325159.1_35225001_1 - 0.00084 18.2 0.8 0.033 13.0 0.5 2.6 2 1 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Lipoxygenase PF00305.17 001324894.1_09326001_3 - 0 1057.5 0.0 0 1057.2 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001324894.1_09326001_3 - 2.8e-18 66.4 0.0 5.1e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain TPR_12 PF13424.4 001325267.1_35229001_1 - 3.5e-31 107.2 15.8 5.3e-11 42.5 0.7 6.3 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.15 001325267.1_35229001_1 - 3.4e-21 73.5 21.0 0.00044 20.0 1.1 8.1 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_1 PF00515.26 001325267.1_35229001_1 - 3.6e-20 70.7 19.1 2.7e-06 26.8 0.9 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.4 001325267.1_35229001_1 - 1.7e-17 61.9 12.3 0.0012 18.6 0.3 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.4 001325267.1_35229001_1 - 3.8e-16 58.3 11.8 0.0093 15.7 0.0 8.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.4 001325267.1_35229001_1 - 1.2e-14 53.0 13.1 0.0078 16.2 0.7 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.4 001325267.1_35229001_1 - 3.5e-08 33.5 2.6 0.64 10.9 0.0 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.4 001325267.1_35229001_1 - 4.4e-05 23.9 2.9 0.2 12.2 0.0 4.8 7 1 0 7 7 5 2 Tetratricopeptide repeat LRR_6 PF13516.4 001325267.1_35229001_1 - 5.7e-05 22.7 25.0 0.37 10.8 0.1 10.0 10 0 0 10 10 10 2 Leucine Rich repeat TPR_6 PF13174.4 001325267.1_35229001_1 - 0.0018 18.6 0.1 27 5.6 0.0 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat LRR_4 PF12799.5 001325267.1_35229001_1 - 0.0019 18.4 24.1 0.03 14.6 0.1 7.6 8 0 0 8 8 6 1 Leucine Rich repeats (2 copies) TPR_11 PF13414.4 001325267.1_35229001_1 - 0.01 15.4 7.4 2.4 7.8 0.1 6.2 7 1 0 7 7 7 0 TPR repeat ANAPC5 PF12862.5 001325267.1_35229001_1 - 0.025 14.5 1.4 0.74 9.8 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 MIT PF04212.16 001325267.1_35229001_1 - 0.16 12.0 4.8 18 5.4 0.4 4.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.4 001325267.1_35229001_1 - 0.41 10.6 2.2 16 5.5 0.1 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.4 001325267.1_35229001_1 - 0.77 10.2 2.7 1.8e+02 2.7 0.0 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat LRR_8 PF13855.4 001325267.1_35229001_1 - 2.2 8.0 15.6 4.1 7.1 0.7 6.4 6 1 1 7 7 7 0 Leucine rich repeat LRR_1 PF00560.31 001325267.1_35229001_1 - 2.2 8.9 22.6 17 6.2 0.1 9.0 10 0 0 10 10 7 0 Leucine Rich Repeat AP2 PF00847.18 001301004.1_44322001_2 - 3e-13 49.7 0.5 5e-13 49.0 0.5 1.4 1 0 0 1 1 1 1 AP2 domain AP2 PF00847.18 001293670.1_44323001_2 - 3.9e-14 52.5 0.6 1e-13 51.2 0.6 1.8 1 0 0 1 1 1 1 AP2 domain Pkinase PF00069.23 001325573.1_35224001_3 - 1.4e-70 237.6 0.0 1.7e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001325573.1_35224001_3 - 1.8e-32 112.5 0.0 2.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001325573.1_35224001_3 - 8.2e-05 21.9 0.0 0.00015 21.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.12 001325573.1_35224001_3 - 0.00025 20.3 0.1 0.0004 19.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.20 001325863.1_35223001_2 - 1.8e-49 167.3 0.0 2.3e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001325863.1_35223001_2 - 3.2e-22 78.9 0.0 5.8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001325863.1_35223001_2 - 0.00039 19.8 0.0 0.00078 18.8 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Pkinase PF00069.23 001324752.1_09324001_1 - 4e-77 259.0 0.0 6.2e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001324752.1_09324001_1 - 1.8e-42 145.3 0.0 2.6e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.17 001324752.1_09324001_1 - 1.2e-13 50.5 0.3 3e-13 49.2 0.3 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.4 001324752.1_09324001_1 - 1.4e-08 34.3 0.0 5.3e-08 32.4 0.0 1.8 1 1 0 2 2 2 1 Kinase-like AdenylateSensor PF16579.3 001324752.1_09324001_1 - 6.8e-07 29.6 0.4 0.0014 18.9 0.0 2.9 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase UBA PF00627.29 001324752.1_09324001_1 - 7.2e-06 25.7 0.1 1.3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.20 001324752.1_09324001_1 - 5.6e-05 22.7 0.3 0.00011 21.7 0.3 1.4 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.9 001324752.1_09324001_1 - 0.0058 16.6 0.3 0.015 15.3 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) UBA_3 PF09288.8 001324752.1_09324001_1 - 0.0088 15.7 0.1 0.035 13.8 0.1 2.0 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain APH PF01636.21 001324752.1_09324001_1 - 0.032 14.0 0.2 0.32 10.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SRF-TF PF00319.16 001325023.1_09322001_1 - 2.2e-22 78.1 0.1 3.7e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001325023.1_09322001_1 - 8.5e-17 61.0 10.4 1.6e-16 60.1 10.4 1.4 1 0 0 1 1 1 1 K-box region Herpes_BLRF2 PF05812.10 001325023.1_09322001_1 - 0.12 12.4 4.1 0.21 11.6 4.1 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein APG6 PF04111.10 001325023.1_09322001_1 - 0.13 11.5 5.3 0.18 11.1 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.13 001325023.1_09322001_1 - 0.56 9.9 5.8 1.8 8.3 0.2 2.7 2 0 0 2 2 2 0 Septum formation initiator HSCB_C PF07743.11 001325023.1_09322001_1 - 4 7.9 9.2 6 7.3 4.7 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain FA_hydroxylase PF04116.11 001325453.1_35223001_1 - 7.6e-21 74.7 22.9 7.6e-21 74.7 22.9 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Lipase_GDSL_2 PF13472.4 001324612.1_09323001_3 - 4.9e-15 56.3 0.0 6.1e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.20 001324612.1_09323001_3 - 6.1e-14 52.3 0.0 8.4e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GRAS PF03514.12 001324816.1_09324001_1 - 5.1e-132 440.2 0.0 6.7e-132 439.8 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family DELLA PF12041.6 001324816.1_09324001_1 - 3.6e-35 119.5 0.3 9.5e-35 118.2 0.3 1.8 1 0 0 1 1 1 1 Transcriptional regulator DELLA protein N terminal Pollen_allerg_1 PF01357.19 001325382.1_35223001_3 - 1.5e-25 88.9 1.2 2.3e-25 88.3 1.2 1.3 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001325382.1_35223001_3 - 3.6e-21 75.1 0.1 6.8e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase WRKY PF03106.13 001325390.1_35225001_1 - 1.9e-52 175.3 18.3 1.7e-26 92.2 3.8 2.5 2 0 0 2 2 2 2 WRKY DNA -binding domain Cyclin_N PF00134.21 001325537.1_35224001_2 - 6e-27 93.8 0.8 1.4e-26 92.6 0.8 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001325537.1_35224001_2 - 3.8e-20 72.0 0.0 8.5e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Annexin PF00191.18 001324677.1_09323001_3 - 1.4e-74 245.9 9.6 5.4e-22 77.5 0.1 4.1 4 0 0 4 4 4 4 Annexin Gluconate_2-dh3 PF13618.4 001324677.1_09323001_3 - 0.011 15.9 0.4 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Thaumatin PF00314.15 001325444.1_35223001_2 - 1.7e-60 204.3 12.0 2.1e-60 204.1 12.0 1.1 1 0 0 1 1 1 1 Thaumatin family RGS PF00615.17 001324639.1_09323001_1 - 7.6e-15 55.1 0.1 1.1e-14 54.6 0.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2070 PF09843.7 001324639.1_09323001_1 - 7.3 4.6 13.0 2.2 6.3 10.4 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Pectinesterase PF01095.17 001325947.1_35225001_3 - 5.2e-150 498.0 4.7 7.1e-150 497.6 4.7 1.1 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.13 001325947.1_35225001_3 - 3.6e-27 95.3 4.8 6.1e-27 94.6 4.8 1.4 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Cu_amine_oxid PF01179.18 001325799.1_35225001_1 - 1.9e-154 514.3 0.0 2.3e-154 514.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.14 001325799.1_35225001_1 - 8.7e-30 103.0 0.0 1.8e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.14 001325799.1_35225001_1 - 7.3e-06 26.0 0.1 9.2e-05 22.5 0.0 2.7 2 1 0 2 2 2 1 Copper amine oxidase, N2 domain Androgen_recep PF02166.14 001325799.1_35225001_1 - 0.3 9.8 2.6 0.45 9.2 2.6 1.1 1 0 0 1 1 1 0 Androgen receptor ComA PF02679.13 001325977.1_35222001_1 - 1.5e-79 266.8 0.0 1.7e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) AP_endonuc_2 PF01261.22 001325977.1_35222001_1 - 0.00085 18.7 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel PDT PF00800.16 001325065.1_09323001_1 - 1.7e-58 197.4 0.0 2.9e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.23 001325065.1_09323001_1 - 0.0019 17.8 0.1 0.0065 16.1 0.0 2.0 2 0 0 2 2 2 1 ACT domain TAXi_C PF14541.4 001324593.1_09323001_1 - 4e-51 172.9 0.0 5.8e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.4 001324593.1_09323001_1 - 1.1e-34 120.1 0.4 1.9e-34 119.3 0.4 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Thaumatin PF00314.15 001324896.1_09322001_2 - 1.2e-62 211.3 12.1 1.4e-62 211.1 12.1 1.0 1 0 0 1 1 1 1 Thaumatin family Pico_P2A PF00947.17 001324896.1_09322001_2 - 0.093 12.6 2.6 0.19 11.6 2.6 1.4 1 0 0 1 1 1 0 Picornavirus core protein 2A Biotin_lipoyl PF00364.20 001325012.1_09322001_1 - 1.4e-24 85.5 0.1 2.7e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.4 001325012.1_09322001_1 - 2.6e-07 30.3 1.2 0.0027 17.4 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.4 001325012.1_09322001_1 - 0.00013 21.7 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.17 001325012.1_09322001_1 - 0.0003 20.6 0.3 0.00062 19.5 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.3 001325012.1_09322001_1 - 0.013 14.6 0.1 1.3 8.0 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Vac14_Fig4_bd PF11916.6 001325012.1_09322001_1 - 0.013 15.0 0.4 0.02 14.4 0.4 1.2 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding YqfD PF06898.9 001325012.1_09322001_1 - 0.097 11.4 3.0 3.3 6.3 0.5 2.2 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD PYNP_C PF07831.11 001325012.1_09322001_1 - 0.21 11.2 0.2 0.65 9.6 0.0 1.8 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain DEC-1_N PF04625.11 001325012.1_09322001_1 - 2.7 6.8 10.6 0.82 8.5 6.3 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Myb_DNA-binding PF00249.29 001325107.1_09325001_2 - 1.5e-07 31.3 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_6 PF13912.4 001324936.1_09323001_2 - 1.1e-24 85.7 15.5 4.7e-13 48.6 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.4 001324936.1_09323001_2 - 4.3e-05 23.9 10.7 0.002 18.7 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001324936.1_09323001_2 - 0.0022 18.2 3.3 0.3 11.5 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.6 001324936.1_09323001_2 - 0.0086 16.2 1.5 0.51 10.6 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.24 001324936.1_09323001_2 - 0.039 14.3 9.3 0.58 10.6 0.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type ZZ PF00569.15 001324936.1_09323001_2 - 0.11 12.2 3.1 4.4 7.1 0.2 3.0 3 0 0 3 3 3 0 Zinc finger, ZZ type ABA_WDS PF02496.14 001319803.1_44322001_1 - 1.7e-35 121.2 25.7 1.7e-35 121.2 25.7 2.0 2 0 0 2 2 2 1 ABA/WDS induced protein DUF3824 PF12868.5 001319803.1_44322001_1 - 0.22 12.1 13.5 0.35 11.4 5.2 2.8 1 1 2 3 3 3 0 Domain of unknwon function (DUF3824) Shisa PF13908.4 001319803.1_44322001_2 - 0.044 13.9 2.3 0.067 13.3 2.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Barwin PF00967.15 001325130.1_35222001_1 - 1.3e-62 208.8 3.3 2.3e-62 208.0 3.3 1.4 1 0 0 1 1 1 1 Barwin family Chitin_bind_1 PF00187.17 001325130.1_35222001_1 - 1.6e-11 44.4 21.8 1.6e-11 44.4 21.8 2.4 3 0 0 3 3 3 1 Chitin recognition protein Acyl-ACP_TE PF01643.15 001325052.1_09323001_1 - 6.3e-98 326.8 0.1 7.8e-98 326.5 0.1 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase PaO PF08417.10 001325995.1_35224001_1 - 9e-21 73.7 0.6 2.2e-20 72.5 0.1 1.9 2 0 0 2 2 2 1 Pheophorbide a oxygenase Rieske PF00355.24 001325995.1_35224001_1 - 6.7e-19 67.5 0.0 1.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ins145_P3_rec PF08709.9 001325995.1_35224001_1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor HABP4_PAI-RBP1 PF04774.13 001324625.1_09323001_1 - 8.7e-27 94.2 15.5 8.7e-27 94.2 15.5 3.3 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.8 001324625.1_09323001_1 - 2.8e-20 72.8 5.1 2.8e-20 72.8 5.1 3.0 3 0 0 3 3 3 1 Stm1 Spore_III_AF PF09581.8 001324625.1_09323001_1 - 0.0064 16.4 7.2 0.009 15.9 7.2 1.2 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) WRKY PF03106.13 001324653.1_09325001_2 - 3.7e-52 174.4 18.2 3.8e-26 91.1 4.9 2.4 2 0 0 2 2 2 2 WRKY DNA -binding domain Pkinase PF00069.23 001325195.1_35222001_1 - 5.3e-74 248.8 0.0 6.1e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001325195.1_35222001_1 - 8.7e-43 146.3 0.0 1.1e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001325195.1_35222001_1 - 3e-07 29.9 0.0 2.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.4 001325195.1_35222001_1 - 0.072 12.6 0.1 5.5 6.4 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.9 001325195.1_35222001_1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Sec7 PF01369.18 001326179.1_35229001_1 - 1.4e-59 200.8 0.1 2.4e-59 200.0 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.5 001326179.1_35229001_1 - 5.2e-29 101.1 2.8 5.2e-29 101.1 2.8 3.5 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SAMP PF05924.9 001326179.1_35229001_1 - 3.6 6.9 9.4 0.21 10.8 2.7 2.4 2 0 0 2 2 2 0 SAMP Motif polyprenyl_synt PF00348.15 001323432.1_48523001_1 - 1.6e-59 200.9 0.0 2.3e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Gln-synt_C PF00120.22 001324595.1_09323001_1 - 3.9e-16 58.9 0.0 1.8e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001324595.1_09323001_1 - 6.4e-11 41.7 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Terpene_synth_C PF03936.14 001325127.1_09324001_1 - 5.9e-98 327.3 6.3 8.2e-98 326.9 6.3 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001325127.1_09324001_1 - 9.1e-56 188.4 0.1 1.6e-55 187.6 0.1 1.4 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain DUF3416 PF11896.6 001325127.1_09324001_1 - 0.13 12.4 0.0 13 5.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3416) CoA_binding PF02629.17 001324746.1_09322001_1 - 4e-32 110.6 0.9 4e-32 110.6 0.9 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.17 001324746.1_09322001_1 - 5.1e-23 81.4 0.6 9.1e-23 80.6 0.6 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.4 001324746.1_09322001_1 - 1.6e-10 40.8 0.0 3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.4 001324746.1_09322001_1 - 0.00023 21.5 0.8 0.00038 20.8 0.0 1.8 2 1 0 2 2 2 1 CoA binding domain adh_short_C2 PF13561.4 001293250.1_44323001_2 - 1.3e-38 132.7 0.1 1.8e-38 132.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001293250.1_44323001_2 - 2.5e-25 88.9 0.0 3.5e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAM PF02365.13 001293271.1_44323001_2 - 4e-28 98.0 0.1 7.9e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein DUF2967 PF11179.6 001293271.1_44323001_2 - 3.7 6.8 10.3 0.19 11.0 4.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) SRF-TF PF00319.16 001293262.1_44323001_2 - 1.9e-21 75.1 0.2 3.7e-21 74.2 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001293262.1_44323001_2 - 3.8e-14 52.5 16.0 3.8e-14 52.5 16.0 1.6 2 0 0 2 2 2 1 K-box region QRPTase_C PF01729.17 001293262.1_44323001_2 - 0.04 13.6 0.5 0.07 12.8 0.5 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Pollen_allerg_1 PF01357.19 001293252.1_44323001_2 - 2.3e-28 97.9 1.3 4.4e-28 97.0 1.3 1.5 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001293252.1_44323001_2 - 3.3e-22 78.4 1.0 5.3e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Lytic transglycolase SRF-TF PF00319.16 001319802.1_44322001_1 - 4.2e-26 90.0 0.3 7.6e-26 89.2 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001319802.1_44322001_1 - 7.2e-24 83.7 10.9 1.3e-23 82.9 10.9 1.4 1 0 0 1 1 1 1 K-box region DUF972 PF06156.11 001319802.1_44322001_1 - 0.023 15.2 1.5 0.059 13.9 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Laminin_I PF06008.12 001319802.1_44322001_1 - 0.44 10.1 9.7 0.73 9.4 7.2 1.9 1 1 0 1 1 1 0 Laminin Domain I ZapB PF06005.10 001319802.1_44322001_1 - 0.84 10.0 14.0 0.16 12.3 5.3 2.4 1 1 1 2 2 2 0 Cell division protein ZapB TSC22 PF01166.16 001319802.1_44322001_1 - 1.7 8.9 11.2 0.19 11.9 3.1 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Pec_lyase_C PF00544.17 001293272.1_44324001_2 - 1.6e-21 76.8 5.5 8.3e-21 74.4 5.5 1.9 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.4 001293272.1_44324001_2 - 1.4e-05 24.8 4.1 2.5e-05 24.0 4.1 1.5 1 0 0 1 1 1 1 Right handed beta helix region 2OG-FeII_Oxy PF03171.18 001293263.1_44323001_2 - 1e-18 67.5 0.0 1.7e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001293263.1_44323001_2 - 1.4e-13 51.5 0.0 2.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ENOD40 PF08247.9 001293263.1_44323001_3 - 0.47 10.4 3.5 0.45 10.5 0.5 2.8 2 0 0 2 2 2 0 ENOD40 protein PBP PF01161.18 001293253.1_44322001_1 - 3.2e-13 50.0 0.0 3.6e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SQS_PSY PF00494.17 001293259.1_44323001_1 - 1.2e-72 244.5 0.2 1.4e-72 244.2 0.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase PsaD PF02531.14 001288859.1_12722001_1 - 1.1e-67 225.6 0.1 1.4e-67 225.2 0.1 1.1 1 0 0 1 1 1 1 PsaD FAP PF07174.9 001288859.1_12722001_1 - 0.0042 16.4 2.7 0.0064 15.8 2.7 1.2 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) Sucrose_synth PF00862.17 001288308.1_48626001_1 - 4.4e-291 965.8 0.0 5.5e-291 965.5 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001288308.1_48626001_1 - 2.7e-30 105.1 0.0 4.8e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001288308.1_48626001_1 - 1.4e-09 38.4 0.0 2.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001288308.1_48626001_1 - 9.3e-05 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_CodY PF08222.9 001288308.1_48626001_1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain SRF-TF PF00319.16 001293268.1_44322001_1 - 7.3e-21 73.3 1.5 8e-21 73.1 0.2 1.8 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001293268.1_44322001_1 - 2e-15 56.6 17.0 3.5e-15 55.8 17.0 1.4 1 0 0 1 1 1 1 K-box region DUF2201 PF09967.7 001293268.1_44322001_1 - 0.078 13.0 0.1 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 VWA-like domain (DUF2201) bZIP_1 PF00170.19 001293268.1_44322001_1 - 0.49 10.4 8.9 0.72 9.9 0.2 2.8 3 0 0 3 3 3 0 bZIP transcription factor p450 PF00067.20 001297461.1_14824001_1 - 8.1e-17 61.0 0.0 2.6e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 PBP_sp32 PF07222.10 001297461.1_14824001_2 - 0.42 9.9 1.6 0.64 9.3 1.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GRAS PF03514.12 001294357.1_29825001_2 - 1.4e-114 382.8 0.0 1.7e-114 382.5 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family MRP-S31 PF15433.4 001294357.1_29825001_2 - 0.015 14.9 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 NAM PF02365.13 001302287.1_45323001_1 - 2e-30 105.4 0.5 3.2e-30 104.7 0.5 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein Fer2 PF00111.25 001302391.1_45322001_3 - 2.8e-20 71.9 0.2 4.2e-20 71.3 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Peptidase_S10 PF00450.20 001326502.1_44324001_2 - 2.1e-124 416.0 0.4 2.8e-124 415.6 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ecTbetaR2 PF08917.8 001326502.1_44324001_2 - 0.11 12.3 1.0 0.18 11.6 1.0 1.2 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain p450 PF00067.20 001326506.1_44324001_1 - 6.9e-76 255.7 0.0 8.6e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001326514.1_44324001_1 - 1e-104 350.7 0.0 1.2e-104 350.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Auxin_resp PF06507.11 001326507.1_44325001_1 - 2.1e-31 107.8 0.0 3.9e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Auxin response factor B3 PF02362.19 001326507.1_44325001_1 - 1.5e-22 79.2 0.0 3.1e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 B3 DNA binding domain AUX_IAA PF02309.14 001326507.1_44325001_1 - 2e-13 50.6 0.6 2.2e-10 40.7 0.6 2.5 1 1 0 1 1 1 1 AUX/IAA family p450 PF00067.20 001326512.1_44324001_1 - 4e-103 345.5 0.0 5.1e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRF-TF PF00319.16 001326510.1_44322001_1 - 8.1e-26 89.1 0.4 2.1e-25 87.8 0.4 1.8 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001326510.1_44322001_1 - 6.6e-16 58.1 11.4 1.6e-15 56.9 11.4 1.6 1 0 0 1 1 1 1 K-box region Glyco_hydro_2 PF00703.19 001327169.1_24427001_3 - 6.9e-10 39.5 0.0 1.7e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.15 001327169.1_24427001_3 - 3.4e-05 23.0 0.0 6.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.23 001327060.1_24423001_3 - 1.7e-70 237.3 0.0 2.1e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001327060.1_24423001_3 - 2.9e-33 115.1 0.0 4.1e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001327060.1_24423001_3 - 2.2e-05 23.8 0.1 3.7e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001327060.1_24423001_3 - 0.0036 16.5 0.0 0.024 13.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001327060.1_24423001_3 - 0.007 16.2 0.2 0.026 14.3 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family NAM PF02365.13 001326980.1_24423001_1 - 4.8e-25 88.1 0.3 9.6e-25 87.1 0.3 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein WRKY PF03106.13 001327508.1_24422001_3 - 8.5e-26 90.0 7.7 9.1e-26 89.9 4.7 2.2 2 0 0 2 2 2 1 WRKY DNA -binding domain Sucrose_synth PF00862.17 001326810.1_24426001_2 - 3.2e-283 939.9 0.0 4.2e-283 939.5 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001326810.1_24426001_2 - 2e-31 108.8 0.0 3.5e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001326810.1_24426001_2 - 6.2e-10 39.5 0.0 1.5e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001326810.1_24426001_2 - 0.0036 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.25 001326810.1_24426001_2 - 0.07 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain SRF-TF PF00319.16 001326820.1_24423001_2 - 7.6e-26 89.2 0.3 1.5e-25 88.3 0.3 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001326820.1_24423001_2 - 1.4e-16 60.3 24.2 2.3e-16 59.6 24.2 1.4 1 0 0 1 1 1 1 K-box region GDA1_CD39 PF01150.15 001326798.1_24423001_1 - 5e-103 344.9 0.0 6e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.14 001326798.1_24423001_1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Cellulose_synt PF03552.12 001327019.1_24427001_2 - 0 1342.4 0.0 0 1342.0 0.0 1.2 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001327019.1_24427001_2 - 5.6e-18 64.7 3.5 1.1e-17 63.7 3.5 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001327019.1_24427001_2 - 6.6e-07 29.3 0.3 6.6e-07 29.3 0.3 2.9 4 0 0 4 4 4 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001327019.1_24427001_2 - 0.0011 18.5 8.8 0.0028 17.2 8.8 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.14 001327019.1_24427001_2 - 0.0075 16.3 3.3 0.019 15.0 3.3 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Di19_C PF14571.4 001326734.1_24422001_1 - 1.1e-36 125.3 3.1 1.9e-36 124.6 3.1 1.3 1 0 0 1 1 1 1 Stress-induced protein Di19, C-terminal zf-Di19 PF05605.10 001326734.1_24422001_1 - 6e-21 74.4 5.2 9e-21 73.8 5.2 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.4 001326734.1_24422001_1 - 0.36 11.6 5.0 1.3 9.9 2.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001326734.1_24422001_1 - 0.43 11.0 2.2 3.6 8.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain WRKY PF03106.13 001327220.1_24423001_1 - 6.7e-26 90.3 0.5 1.3e-25 89.4 0.5 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain Pkinase PF00069.23 001327555.1_24423001_2 - 1.8e-65 220.8 0.0 2.6e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001327555.1_24423001_2 - 6.6e-30 104.1 0.0 1e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001327555.1_24423001_2 - 0.0021 17.3 0.0 0.0047 16.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.12 001327555.1_24423001_2 - 0.01 15.1 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-Nse PF11789.6 001327555.1_24423001_3 - 0.06 13.0 1.3 0.12 12.1 1.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HSF_DNA-bind PF00447.15 001327346.1_24423001_2 - 3.6e-29 101.1 1.4 3.6e-29 101.1 1.4 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding TolA_bind_tri PF16331.3 001327346.1_24423001_2 - 0.064 13.2 1.6 0.16 12.0 1.6 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3450 PF11932.6 001327346.1_24423001_2 - 0.083 12.0 3.3 0.12 11.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.12 001327346.1_24423001_2 - 0.54 9.9 4.7 0.77 9.4 4.7 1.1 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.11 001327346.1_24423001_2 - 1 7.8 3.9 1.4 7.3 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) JIP_LZII PF16471.3 001327346.1_24423001_2 - 1.3 9.2 5.5 0.25 11.4 1.8 1.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II SRF-TF PF00319.16 001326865.1_24422001_2 - 1.5e-23 81.8 0.1 3.6e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001326865.1_24422001_2 - 3.5e-23 81.5 9.8 3.5e-23 81.5 9.8 1.6 2 0 0 2 2 2 1 K-box region Radical_SAM_N PF08497.8 001326865.1_24422001_2 - 0.051 12.7 0.1 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal DAHP_synth_2 PF01474.14 001326945.1_24424001_1 - 3.2e-195 648.6 0.0 3.7e-195 648.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family WRKY PF03106.13 001327729.1_24423001_2 - 1.4e-24 86.1 1.2 2.7e-24 85.2 1.2 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain DUF3510 PF12022.6 001327729.1_24423001_2 - 0.048 13.9 0.9 0.1 12.8 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) RP-C_C PF11800.6 001327729.1_24423001_2 - 0.13 12.2 2.9 0.26 11.2 2.9 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region OAD_gamma PF04277.11 001327729.1_24423001_2 - 0.85 10.1 2.4 1.5 9.4 0.1 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain AATF-Che1 PF13339.4 001327729.1_24423001_2 - 2.4 8.7 8.8 0.42 11.1 5.0 1.7 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor HSF_DNA-bind PF00447.15 001326901.1_24423001_3 - 1.9e-28 98.7 0.4 4.4e-28 97.6 0.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding IFP_35_N PF07334.11 001326901.1_24423001_3 - 0.014 15.3 3.2 0.031 14.2 3.2 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Borrelia_orfA PF02414.13 001326901.1_24423001_3 - 0.033 13.7 2.8 0.047 13.2 2.8 1.2 1 0 0 1 1 1 0 Borrelia ORF-A DUF2508 PF10704.7 001326901.1_24423001_3 - 0.24 11.5 2.7 0.5 10.4 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) PEP-utilisers_N PF05524.11 001326901.1_24423001_3 - 0.29 11.2 2.0 0.49 10.4 2.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal HSP70 PF00012.18 001327564.1_24425001_3 - 5.1e-265 880.2 13.8 5.8e-265 880.0 13.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001327564.1_24425001_3 - 4.3e-17 61.8 0.8 7.2e-16 57.8 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.4 001327564.1_24425001_3 - 0.0001 22.6 5.1 0.34 11.2 0.2 3.8 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.16 001327564.1_24425001_3 - 0.0021 17.2 2.1 0.18 10.9 0.2 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase FGGY_C PF02782.14 001327564.1_24425001_3 - 0.0056 16.3 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HOIP-UBA PF16678.3 001327564.1_24425001_3 - 0.017 15.0 2.9 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase DDR PF08841.8 001327564.1_24425001_3 - 0.025 13.5 0.3 0.19 10.5 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Radial_spoke_3 PF06098.9 001327564.1_24425001_3 - 0.041 13.0 8.5 0.084 12.0 8.5 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 SRF-TF PF00319.16 001327270.1_24422001_1 - 1.3e-24 85.2 0.3 2.5e-24 84.4 0.3 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001327270.1_24422001_1 - 5.1e-22 77.7 6.6 8.6e-22 77.0 6.6 1.4 1 0 0 1 1 1 1 K-box region PUB PF09409.8 001327270.1_24422001_1 - 0.02 14.7 0.9 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 PUB domain ABC_tran_CTD PF16326.3 001327270.1_24422001_1 - 0.66 10.1 4.1 18 5.5 0.0 3.2 3 1 0 3 3 3 0 ABC transporter C-terminal domain NAM PF02365.13 001327107.1_24424001_2 - 5.4e-25 87.9 0.3 9.2e-25 87.2 0.3 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein FMN_red PF03358.13 001327443.1_24422001_1 - 3.1e-13 49.6 0.0 4.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.15 001327443.1_24422001_1 - 2.9e-06 27.0 0.0 3.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.23 001327443.1_24422001_1 - 0.00029 20.9 0.1 0.00063 19.8 0.1 1.8 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.5 001327443.1_24422001_1 - 0.029 14.5 0.0 1.8 8.7 0.0 2.2 1 1 1 2 2 2 0 Flavodoxin domain AUX_IAA PF02309.14 001327452.1_24423001_3 - 4e-82 275.6 1.3 3.3e-81 272.5 1.3 2.1 1 1 0 1 1 1 1 AUX/IAA family Herpes_PAP PF03325.11 001327452.1_24423001_3 - 0.83 8.6 6.0 1.2 8.0 6.0 1.2 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein Pkinase PF00069.23 001327634.1_24424001_1 - 1.9e-69 233.9 0.0 2.5e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001327634.1_24424001_1 - 4.5e-33 114.5 0.0 6.5e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001327634.1_24424001_1 - 0.00042 19.6 0.0 0.00064 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001327634.1_24424001_1 - 0.0013 18.0 0.1 0.002 17.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SynMuv_product PF06047.9 001328219.1_48424001_1 - 1.8e-48 162.8 2.9 1.8e-48 162.8 2.9 3.1 3 1 1 4 4 4 1 Ras-induced vulval development antagonist ADH_zinc_N PF00107.24 001297469.1_14824001_1 - 9e-25 86.9 0.0 1.5e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001297469.1_14824001_1 - 1.1e-21 76.6 0.3 2.3e-21 75.6 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.3 001297469.1_14824001_1 - 6.2e-05 22.4 0.1 0.00017 21.0 0.1 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.19 001297469.1_14824001_1 - 9.3e-05 21.7 0.2 0.00015 21.0 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.17 001297469.1_14824001_1 - 0.026 13.7 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.16 001297469.1_14824001_1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.12 001297469.1_14824001_1 - 0.075 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aminotran_1_2 PF00155.19 001297535.1_14825001_1 - 3.3e-109 365.2 0.0 4e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001297535.1_14825001_1 - 0.0068 15.6 0.0 0.0099 15.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase iPGM_N PF06415.11 001297535.1_14825001_1 - 0.014 14.7 0.0 0.042 13.2 0.0 1.8 2 0 0 2 2 2 0 BPG-independent PGAM N-terminus (iPGM_N) Response_reg PF00072.22 001297539.1_14826001_1 - 9.2e-19 67.5 0.0 2.6e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.24 001297539.1_14826001_1 - 7.4e-12 45.8 0.0 1.8e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.24 001297539.1_14826001_1 - 1.4e-05 25.5 0.0 3.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.23 001297539.1_14826001_1 - 4.9e-05 23.2 3.5 0.00029 20.7 0.1 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain RPE65 PF03055.13 001297498.1_14824001_1 - 1.9e-91 307.2 0.0 2.2e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Glyco_hydro_19 PF00182.17 001297544.1_14823001_1 - 3.2e-121 403.4 4.1 3.2e-121 403.4 4.1 1.9 2 0 0 2 2 2 1 Chitinase class I Chitin_bind_1 PF00187.17 001297544.1_14823001_1 - 2.2e-15 56.7 20.1 2.2e-15 56.7 20.1 2.4 2 0 0 2 2 2 1 Chitin recognition protein DUF1704 PF08014.9 001297544.1_14823001_2 - 0.083 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) NAM PF02365.13 001297506.1_14823001_2 - 3e-28 98.4 0.2 6.7e-28 97.2 0.2 1.6 1 0 0 1 1 1 1 No apical meristem (NAM) protein GalKase_gal_bdg PF10509.7 001297546.1_14824001_3 - 1e-22 79.3 0.0 1.8e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.24 001297546.1_14824001_3 - 6.8e-14 51.7 0.1 2.8e-13 49.7 0.5 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.11 001297546.1_14824001_3 - 1.4e-13 50.9 0.0 3.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Glyco_hydro_16 PF00722.19 001297514.1_14823001_3 - 6.7e-63 211.2 1.3 8.7e-63 210.8 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 XET_C PF06955.10 001297514.1_14823001_3 - 1e-20 73.2 0.8 2.1e-20 72.3 0.8 1.5 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus Aminotran_5 PF00266.17 001297516.1_14823001_3 - 7.7e-33 113.8 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_9 PF00759.17 001297520.1_14825001_2 - 3.4e-125 418.6 5.4 4e-125 418.3 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 AP2 PF00847.18 001328441.1_14822001_1 - 2.5e-14 53.1 0.1 2.5e-14 53.1 0.1 2.2 2 0 0 2 2 2 1 AP2 domain IF4E PF01652.16 001328441.1_14822001_1 - 0.048 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E Terpene_synth_C PF03936.14 001328459.1_14824001_1 - 4.1e-102 341.0 11.3 4.1e-102 341.0 11.3 1.9 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001328459.1_14824001_1 - 8.8e-57 191.7 6.8 2.5e-56 190.3 5.1 2.2 2 0 0 2 2 2 1 Terpene synthase, N-terminal domain RdRP PF05183.10 001328468.1_14827001_1 - 5.6e-183 609.6 0.0 6.9e-183 609.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.20 001328468.1_14827001_1 - 0.073 12.8 0.0 0.96 9.2 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_kinase PF00696.26 001328443.1_14826001_2 - 1e-35 123.4 0.1 1.6e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.20 001328443.1_14826001_2 - 4.4e-09 35.2 0.3 2e-06 26.5 0.2 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Transferase PF02458.13 001328466.1_14824001_1 - 1.6e-76 257.6 0.0 1.9e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Transferase family Sod_Cu PF00080.18 001328450.1_14822001_1 - 5.6e-17 62.1 0.0 1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.24 001328450.1_14822001_1 - 3.8e-11 43.1 1.0 9.3e-11 41.9 1.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain FMO-like PF00743.17 001328448.1_14823001_3 - 2e-32 112.2 0.0 3.3e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 001328448.1_14823001_3 - 3.4e-29 101.9 0.0 4.1e-25 88.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 001328448.1_14823001_3 - 1.4e-19 70.3 0.1 3.6e-16 59.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001328448.1_14823001_3 - 5.3e-17 61.9 0.0 2.6e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001328448.1_14823001_3 - 3.6e-07 29.6 0.4 9.7e-06 24.9 0.1 2.7 2 1 1 3 3 3 1 FAD binding domain Pyr_redox PF00070.25 001328448.1_14823001_3 - 1.6e-06 28.4 0.1 0.12 12.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001328448.1_14823001_3 - 7.8e-06 25.9 0.1 2.9e-05 24.1 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.4 001328448.1_14823001_3 - 1.6e-05 24.8 0.0 0.072 13.0 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.22 001328448.1_14823001_3 - 5.3e-05 22.9 0.2 0.01 15.4 0.1 3.0 3 1 1 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.12 001328448.1_14823001_3 - 0.00026 19.7 1.2 0.054 12.0 0.3 3.7 5 0 0 5 5 5 1 HI0933-like protein FAD_binding_2 PF00890.22 001328448.1_14823001_3 - 0.00083 18.4 0.4 0.0038 16.2 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.15 001328448.1_14823001_3 - 0.0029 16.7 0.1 0.063 12.4 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.10 001328448.1_14823001_3 - 0.0074 15.2 0.3 0.37 9.7 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.18 001328448.1_14823001_3 - 0.02 14.8 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.14 001328448.1_14823001_3 - 0.027 14.0 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.16 001328448.1_14823001_3 - 0.031 14.4 0.0 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.20 001328448.1_14823001_3 - 0.065 12.2 0.0 2.5 6.9 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A IlvN PF07991.10 001328448.1_14823001_3 - 0.12 11.9 0.0 7.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FMO-like PF00743.17 001328467.1_14823001_1 - 5.9e-34 117.3 0.0 9.4e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 001328467.1_14823001_1 - 5.9e-28 97.8 0.0 1.2e-24 87.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 001328467.1_14823001_1 - 3.6e-17 62.4 0.0 6.4e-12 45.1 0.0 3.0 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001328467.1_14823001_1 - 1.4e-12 47.3 0.0 2.4e-09 36.7 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001328467.1_14823001_1 - 7.6e-06 25.9 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.25 001328467.1_14823001_1 - 1e-05 25.8 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001328467.1_14823001_1 - 1.1e-05 24.7 0.1 2.7e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.4 001328467.1_14823001_1 - 0.00016 21.6 0.4 0.59 10.0 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.22 001328467.1_14823001_1 - 0.00049 19.7 1.5 0.11 12.0 0.2 3.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.15 001328467.1_14823001_1 - 0.00058 19.0 0.1 0.016 14.3 0.0 2.8 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.18 001328467.1_14823001_1 - 0.0017 18.3 0.0 0.94 9.4 0.0 3.1 4 0 0 4 4 3 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.22 001328467.1_14823001_1 - 0.003 16.8 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.17 001328467.1_14823001_1 - 0.0066 15.7 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.12 001328467.1_14823001_1 - 0.0088 14.6 0.2 0.066 11.8 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.20 001328467.1_14823001_1 - 0.016 14.1 0.0 4.7 6.1 0.0 2.8 4 0 0 4 4 4 0 Glucose inhibited division protein A TrkA_N PF02254.16 001328467.1_14823001_1 - 0.032 14.4 0.0 5.8 7.1 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain FAD_binding_2 PF00890.22 001328467.1_14823001_1 - 0.046 12.7 0.7 0.086 11.8 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.14 001328467.1_14823001_1 - 0.065 12.8 0.1 6.8 6.2 0.0 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.10 001328467.1_14823001_1 - 0.071 12.0 0.5 0.5 9.2 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.4 001328467.1_14823001_1 - 0.099 13.0 0.0 0.61 10.4 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding DNA_methylase PF00145.15 001293858.1_29826001_1 - 6e-12 45.4 0.0 8.1e-06 25.3 0.0 2.5 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase UBA PF00627.29 001293858.1_29826001_1 - 0.035 13.9 0.0 14 5.5 0.0 3.0 3 0 0 3 3 3 0 UBA/TS-N domain AP2 PF00847.18 001294023.1_29824001_1 - 9.4e-09 35.3 5.0 1.3e-08 34.8 2.5 2.2 2 0 0 2 2 2 1 AP2 domain Glyco_hydro_100 PF12899.5 001294124.1_29825001_1 - 2.3e-213 708.5 0.0 2.7e-213 708.3 0.0 1.0 1 0 0 1 1 1 1 Alkaline and neutral invertase GDE_C PF06202.12 001294124.1_29825001_1 - 2.7e-05 23.1 0.7 0.29 9.9 0.0 3.0 2 1 0 2 2 2 2 Amylo-alpha-1,6-glucosidase Linker_histone PF00538.17 001293834.1_29824001_3 - 2e-10 40.8 0.0 4.8e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Myb_DNA-binding PF00249.29 001293834.1_29824001_3 - 2.6e-07 30.5 0.5 5.5e-07 29.5 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001293834.1_29824001_3 - 0.00013 22.0 0.2 0.00028 21.0 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain CHDCT2 PF08074.9 001293834.1_29824001_3 - 0.27 11.3 1.5 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Alanine_zipper PF11839.6 001293834.1_29824001_3 - 0.47 10.6 24.1 0.87 9.8 24.1 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DIOX_N PF14226.4 001293838.1_29823001_1 - 1.2e-25 90.5 0.1 1.9e-25 89.8 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.18 001293838.1_29823001_1 - 2.7e-25 88.6 0.0 6.7e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_3 PF07859.11 001294353.1_29823001_1 - 1.1e-60 204.9 0.0 1.4e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.26 001294353.1_29823001_1 - 8.5e-08 31.4 0.3 2.9e-07 29.7 0.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.5 001294353.1_29823001_1 - 0.00013 20.8 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2974 PF11187.6 001294353.1_29823001_1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.6 001294353.1_29823001_1 - 0.038 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.7 001294353.1_29823001_1 - 0.041 12.6 0.0 0.093 11.4 0.0 1.5 1 1 0 1 1 1 0 Steryl acetyl hydrolase Aminotran_3 PF00202.19 001293859.1_29824001_3 - 3.8e-89 299.0 0.0 4.8e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Dehydrin PF00257.17 001294078.1_29822001_2 - 1.7e-41 142.4 41.8 1.9e-23 83.7 12.7 3.1 1 1 2 3 3 3 3 Dehydrin GDP_Man_Dehyd PF16363.3 001293887.1_29823001_3 - 9.4e-65 219.0 0.0 1.1e-64 218.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.19 001293887.1_29823001_3 - 5.7e-54 183.0 0.0 7.1e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.13 001293887.1_29823001_3 - 3.9e-16 58.9 0.0 1.4e-15 57.1 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.17 001293887.1_29823001_3 - 2e-15 56.4 0.0 3.2e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.23 001293887.1_29823001_3 - 4.8e-09 35.8 0.0 7.8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.15 001293887.1_29823001_3 - 6.5e-09 35.2 0.0 1.3e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.4 001293887.1_29823001_3 - 7.2e-07 29.2 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001293887.1_29823001_3 - 1.1e-05 24.6 0.1 4.7e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein KR PF08659.8 001293887.1_29823001_3 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.16 001293887.1_29823001_3 - 0.0094 15.7 0.0 0.023 14.5 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.16 001293887.1_29823001_3 - 0.02 15.0 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.12 001293887.1_29823001_3 - 0.028 13.8 0.0 0.073 12.5 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.11 001293887.1_29823001_3 - 0.072 12.5 0.1 0.28 10.6 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family SAM_decarbox PF01536.14 001293896.1_29824001_3 - 3.4e-109 365.0 0.0 4.7e-109 364.5 0.0 1.2 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase AdoMetDC_leader PF08132.9 001293896.1_29824001_3 - 2.6e-31 107.3 5.5 2.6e-31 107.3 5.5 2.1 2 0 0 2 2 2 1 S-adenosyl-l-methionine decarboxylase leader peptide Pec_lyase_C PF00544.17 001293910.1_29824001_2 - 6.5e-21 74.8 4.9 3.6e-20 72.3 4.9 1.9 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.4 001293910.1_29824001_2 - 6.3e-06 26.0 3.0 1.1e-05 25.2 3.0 1.4 1 0 0 1 1 1 1 Right handed beta helix region adh_short_C2 PF13561.4 001293918.1_29823001_1 - 1.2e-52 178.7 1.3 5.7e-49 166.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001293918.1_29823001_1 - 7e-10 38.6 0.1 6.7e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Enoyl_reductase PF12241.6 001293918.1_29823001_1 - 0.0013 17.9 0.0 0.29 10.3 0.0 2.2 1 1 1 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region AP2 PF00847.18 001329037.1_29822001_2 - 4.5e-13 49.1 0.1 7.3e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 AP2 domain SRF-TF PF00319.16 001328882.1_29822001_1 - 5.6e-26 89.6 0.2 1.3e-25 88.5 0.2 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001328882.1_29822001_1 - 3.3e-17 62.3 13.1 3.3e-17 62.3 13.1 1.8 1 1 1 2 2 2 1 K-box region Vps54_N PF10475.7 001328882.1_29822001_1 - 0.024 13.8 4.0 0.035 13.3 3.6 1.5 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex USP7_ICP0_bdg PF12436.6 001328882.1_29822001_1 - 0.033 13.5 0.3 0.055 12.7 0.1 1.5 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 Sipho_Gp157 PF05565.9 001328882.1_29822001_1 - 0.093 12.6 9.5 0.21 11.4 4.9 2.4 1 1 1 2 2 2 0 Siphovirus Gp157 APG6 PF04111.10 001328882.1_29822001_1 - 0.12 11.6 9.7 0.17 11.1 9.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 5_3_exonuc PF01367.18 001328882.1_29822001_1 - 0.29 11.6 3.0 11 6.6 0.1 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF1192 PF06698.9 001328882.1_29822001_1 - 0.57 10.2 6.0 4.2 7.4 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) OmpH PF03938.12 001328882.1_29822001_1 - 2.2 8.1 10.3 5.2 6.9 10.3 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-H PF05837.10 001328882.1_29822001_1 - 4.3 7.6 13.7 1.4 9.2 2.4 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.13 001328882.1_29822001_1 - 6.9 6.7 13.0 0.1 12.5 3.8 2.5 2 1 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.23 001328737.1_29823001_1 - 5.7e-70 235.6 0.3 1e-69 234.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001328737.1_29823001_1 - 7.8e-41 139.9 0.0 1.3e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001328737.1_29823001_1 - 1.9e-16 59.8 0.5 4.6e-16 58.6 0.5 1.7 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001328737.1_29823001_1 - 4.5e-06 26.1 0.0 1.1e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.20 001328737.1_29823001_1 - 3.2e-05 23.5 0.2 6.6e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.12 001328737.1_29823001_1 - 0.0024 17.2 1.1 0.0033 16.7 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001328737.1_29823001_1 - 0.087 12.6 0.0 5.1 6.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SQHop_cyclase_C PF13243.4 001328874.1_29825001_1 - 7.8e-55 186.1 0.7 2.4e-50 171.3 0.3 2.7 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.4 001328874.1_29825001_1 - 8.2e-40 136.6 0.1 4.9e-36 124.2 0.0 3.1 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.19 001328874.1_29825001_1 - 2.1e-29 100.8 10.4 4.4e-09 35.8 3.5 4.1 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.8 001328874.1_29825001_1 - 0.0064 15.7 0.0 0.2 10.8 0.0 3.3 4 0 0 4 4 4 1 Pectic acid lyase GATA PF00320.25 001328973.1_29823001_2 - 1e-15 56.9 3.4 1e-15 56.9 3.4 1.9 2 0 0 2 2 2 1 GATA zinc finger Lycopene_cycl PF05834.10 001329163.1_16324001_1 - 1.2e-155 518.2 0.0 1.4e-155 517.9 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.12 001329163.1_16324001_1 - 1.4e-05 24.4 0.2 0.00087 18.5 0.1 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001329163.1_16324001_1 - 0.00035 19.3 0.3 0.031 12.8 0.3 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.22 001329163.1_16324001_1 - 0.0057 16.2 0.0 2.5 7.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.20 001329163.1_16324001_1 - 0.0058 15.6 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.22 001329163.1_16324001_1 - 0.012 14.6 1.1 0.027 13.4 1.2 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.5 001329163.1_16324001_1 - 0.11 11.7 0.5 0.17 11.0 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.4 001329163.1_16324001_1 - 0.3 10.2 1.2 0.53 9.3 1.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.10 001329160.1_16325001_2 - 9.1e-145 482.3 0.0 1.1e-144 482.1 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.12 001329160.1_16325001_2 - 1.9e-07 30.5 0.4 0.0054 15.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001329160.1_16325001_2 - 8.6e-05 22.2 1.3 0.16 11.4 0.7 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.5 001329160.1_16325001_2 - 0.00043 19.6 0.4 0.0008 18.7 0.4 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.15 001329160.1_16325001_2 - 0.00085 18.5 0.8 0.12 11.5 0.1 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.12 001329160.1_16325001_2 - 0.0012 17.5 2.6 0.007 15.0 0.4 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.25 001329160.1_16325001_2 - 0.0014 19.0 0.2 0.49 10.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.12 001329160.1_16325001_2 - 0.0016 17.2 0.6 0.072 11.8 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.4 001329160.1_16325001_2 - 0.0024 17.8 0.5 2.4 8.0 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.4 001329160.1_16325001_2 - 0.0038 16.4 2.6 0.025 13.7 2.6 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001329160.1_16325001_2 - 0.0087 16.2 0.2 0.026 14.6 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.17 001329160.1_16325001_2 - 0.0095 15.1 0.2 0.016 14.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.22 001329160.1_16325001_2 - 0.015 14.2 0.6 0.03 13.3 0.6 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.20 001329160.1_16325001_2 - 0.025 13.5 2.2 0.15 11.0 2.2 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A SQS_PSY PF00494.17 001329177.1_16324001_1 - 4.9e-73 245.7 0.1 6.1e-73 245.4 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase polyprenyl_synt PF00348.15 001329174.1_16323001_2 - 4.3e-56 189.7 0.0 6e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Amino_oxidase PF01593.22 001329170.1_16325001_2 - 2.5e-18 66.5 0.0 3.4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001329170.1_16325001_2 - 2.3e-12 46.9 0.3 8.3e-12 45.1 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.22 001329170.1_16325001_2 - 1.4e-08 34.1 5.7 1.6e-05 24.1 3.1 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.22 001329170.1_16325001_2 - 2.3e-07 30.6 0.5 3.8e-05 23.4 1.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.15 001329170.1_16325001_2 - 5.5e-05 22.4 0.6 0.00017 20.8 0.3 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.12 001329170.1_16325001_2 - 5.8e-05 21.8 0.8 0.0051 15.4 0.8 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.12 001329170.1_16325001_2 - 8.2e-05 21.8 0.8 0.00036 19.7 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.16 001329170.1_16325001_2 - 0.00011 20.8 0.2 0.045 12.1 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_oxidored PF12831.5 001329170.1_16325001_2 - 0.00013 21.4 2.2 0.00024 20.5 2.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.20 001329170.1_16325001_2 - 0.0011 18.0 1.2 0.019 13.9 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.17 001329170.1_16325001_2 - 0.006 15.8 0.8 0.0091 15.2 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.17 001329170.1_16325001_2 - 0.07 12.3 0.3 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 GMC oxidoreductase MCRA PF06100.9 001329170.1_16325001_2 - 0.15 10.7 0.2 0.27 9.9 0.1 1.4 2 0 0 2 2 2 0 MCRA family Pyr_redox PF00070.25 001329170.1_16325001_2 - 4.3 7.8 7.5 15 6.1 1.0 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase SQS_PSY PF00494.17 001329167.1_16324001_3 - 1.3e-72 244.3 0.1 1.8e-72 243.9 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.13 001329173.1_16325001_2 - 4.4e-103 345.5 0.0 5.4e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPP1R35_C PF15503.4 001329173.1_16325001_2 - 0.12 12.0 0.3 0.25 11.0 0.3 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus RPE65 PF03055.13 001329172.1_16325001_3 - 8.8e-104 347.8 0.0 1e-103 347.6 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.13 001329169.1_16325001_3 - 2.9e-102 342.8 0.0 3.5e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FA_hydroxylase PF04116.11 001329176.1_16323001_1 - 6.5e-12 45.8 7.0 1.1e-11 45.1 7.0 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily UPF0233 PF06781.10 001329176.1_16323001_1 - 0.19 11.7 0.7 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) RPE65 PF03055.13 001329178.1_16325001_1 - 3.3e-121 405.2 0.0 3.9e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein bHLH-MYC_N PF14215.4 001330027.1_24324001_1 - 5.1e-52 176.5 0.4 1.1e-51 175.4 0.0 1.8 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 001330027.1_24324001_1 - 7.8e-13 48.1 0.7 1.6e-12 47.1 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tubulin-binding PF00418.17 001330027.1_24324001_1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat p450 PF00067.20 001330047.1_24324001_1 - 1.5e-95 320.5 0.0 1.8e-95 320.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.11 001330013.1_24323001_1 - 1.2e-52 178.7 0.0 1.5e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.4 001330013.1_24323001_1 - 1.9e-06 27.8 0.0 2.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.19 001330013.1_24323001_1 - 3.5e-06 26.5 0.1 7.7e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001330013.1_24323001_1 - 8.5e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.8 001330013.1_24323001_1 - 0.033 14.0 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.10 001330013.1_24323001_1 - 0.056 12.5 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Myb_DNA-binding PF00249.29 001330053.1_24322001_1 - 9.2e-33 112.0 3.3 4.6e-17 61.8 2.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001330053.1_24322001_1 - 1.7e-19 69.7 0.4 4.6e-11 42.7 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001330053.1_24322001_1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 SLIDE CAP_N PF01213.17 001330025.1_24323001_1 - 8.6e-81 271.7 0.0 1.2e-80 271.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.9 001330025.1_24323001_1 - 7.2e-60 201.0 0.2 7.2e-60 201.0 0.2 1.6 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.10 001330025.1_24323001_1 - 0.0023 17.5 4.7 0.0051 16.4 4.7 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C SRP-alpha_N PF04086.11 001330025.1_24323001_1 - 0.28 10.9 1.6 0.41 10.4 1.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PRIMA1 PF16101.3 001330025.1_24323001_1 - 7.7 6.4 10.4 15 5.5 10.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 BURP PF03181.13 001330034.1_24323001_3 - 1.1e-81 273.4 2.5 1.4e-81 273.1 2.5 1.1 1 0 0 1 1 1 1 BURP domain p450 PF00067.20 001330051.1_24323001_1 - 1.2e-64 218.7 0.0 1.7e-56 191.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Sucrose_synth PF00862.17 001330031.1_24327001_2 - 1.7e-270 897.9 0.0 2.1e-270 897.6 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001330031.1_24327001_2 - 9.9e-34 116.2 0.0 1.9e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001330031.1_24327001_2 - 1.1e-10 41.9 0.0 2.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001330031.1_24327001_2 - 0.00049 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_CodY PF08222.9 001330031.1_24327001_2 - 0.044 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 CodY helix-turn-helix domain DUF4913 PF16259.3 001330031.1_24327001_2 - 0.08 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) Response_reg PF00072.22 001330039.1_24325001_1 - 5.9e-19 68.2 0.4 2.4e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.24 001330039.1_24325001_1 - 7.5e-11 42.6 0.0 1.7e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain HisKA PF00512.23 001330039.1_24325001_1 - 4e-06 26.6 0.2 4e-06 26.6 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.24 001330039.1_24325001_1 - 6.3e-06 26.6 0.0 1.5e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase bHLH-MYC_N PF14215.4 001330033.1_24324001_1 - 1.8e-57 194.2 0.0 4.6e-57 192.9 0.0 1.7 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 001330033.1_24324001_1 - 3.8e-11 42.6 0.5 8.1e-11 41.6 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA_assoc_2 PF16193.3 001330033.1_24324001_1 - 0.016 15.4 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain Cu-oxidase_3 PF07732.13 001330043.1_24324001_2 - 4.9e-39 132.9 2.9 8.4e-39 132.1 0.7 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.12 001330043.1_24324001_2 - 1e-37 128.8 11.7 1.1e-36 125.4 0.6 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.20 001330043.1_24324001_2 - 6.4e-32 110.7 0.6 1.9e-31 109.2 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase DUF5001 PF16392.3 001330043.1_24324001_2 - 0.18 11.9 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function FA_hydroxylase PF04116.11 001330046.1_24322001_1 - 9.5e-29 100.3 17.0 9.5e-29 100.3 17.0 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sucrose_synth PF00862.17 001330029.1_24326001_1 - 2.8e-284 943.4 0.0 3.7e-284 943.0 0.0 1.2 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001330029.1_24326001_1 - 1.9e-30 105.6 0.0 3.7e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001330029.1_24326001_1 - 3e-10 40.5 0.0 7.2e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001330029.1_24326001_1 - 0.00021 21.5 0.0 0.00053 20.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.25 001330029.1_24326001_1 - 0.067 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain TMIE PF16038.3 001330029.1_24326001_1 - 1 9.2 4.5 2.5 7.9 4.5 1.6 1 0 0 1 1 1 0 TMIE protein DUF641 PF04859.10 001330014.1_24322001_1 - 0.0057 16.9 6.9 0.0057 16.9 6.9 2.4 1 1 0 2 2 2 1 Plant protein of unknown function (DUF641) XkdW PF09636.8 001330014.1_24322001_1 - 0.63 10.0 7.5 0.63 10.0 0.4 2.9 1 1 2 3 3 3 0 XkdW protein Exonuc_VII_L PF02601.13 001330014.1_24322001_1 - 1.3 8.4 7.2 1.6 8.1 7.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.6 001330014.1_24322001_1 - 2.1 7.0 11.0 2.7 6.6 11.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter D5_N PF08706.9 001330014.1_24322001_1 - 6.6 6.8 9.0 31 4.7 9.1 2.1 1 1 1 2 2 2 0 D5 N terminal like Sod_Cu PF00080.18 001330012.1_24322001_1 - 2e-45 154.3 2.9 2e-45 154.3 2.9 1.6 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) p450 PF00067.20 001330024.1_24323001_1 - 1.8e-65 221.4 0.0 3.5e-58 197.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Sucrose_synth PF00862.17 001330032.1_24326001_1 - 5.6e-291 965.5 0.0 7.6e-291 965.1 0.0 1.2 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001330032.1_24326001_1 - 3.2e-30 104.8 0.0 6.4e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001330032.1_24326001_1 - 4.8e-09 36.6 0.0 9.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001330032.1_24326001_1 - 0.0025 18.1 0.0 0.0063 16.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 OTCace PF00185.22 001330032.1_24326001_1 - 0.071 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Glyco_transf_20 PF00982.19 001330040.1_24327001_3 - 1.1e-187 624.4 0.0 1.3e-187 624.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.14 001330040.1_24327001_3 - 1.3e-77 259.9 0.0 2e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.10 001330040.1_24327001_3 - 1.8e-08 34.3 0.0 0.00037 20.2 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase p450 PF00067.20 001330036.1_24324001_1 - 8e-17 61.0 0.0 6e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 Calreticulin PF00262.16 001330021.1_24323001_1 - 1.8e-79 267.1 19.3 1e-59 202.1 5.9 2.3 2 1 1 3 3 3 2 Calreticulin family CDC45 PF02724.12 001330021.1_24323001_1 - 0.0051 15.0 11.1 0.024 12.8 11.9 1.7 2 0 0 2 2 2 1 CDC45-like protein DHR-2 PF06920.11 001330044.1_24329001_1 - 3.5e-156 520.8 0.0 4.8e-156 520.4 0.0 1.2 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.4 001330044.1_24329001_1 - 6.1e-35 120.7 0.0 5.1e-34 117.7 0.0 2.4 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins Sucrose_synth PF00862.17 001330054.1_24326001_2 - 3.4e-283 939.8 0.0 4.3e-283 939.5 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001330054.1_24326001_2 - 8.9e-32 109.9 0.0 1.7e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001330054.1_24326001_2 - 3.3e-10 40.4 0.0 8.2e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001330054.1_24326001_2 - 0.00022 21.5 0.0 0.00057 20.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.25 001330054.1_24326001_2 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain polyprenyl_synt PF00348.15 001330011.1_24323001_2 - 1.9e-94 315.4 0.0 2.4e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Zein-binding PF04576.13 001330011.1_24323001_2 - 0.029 14.5 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Zein-binding Epimerase PF01370.19 001330008.1_24323001_2 - 1.4e-25 90.1 0.0 1.9e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001330008.1_24323001_2 - 1.3e-17 63.6 0.0 1.8e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001330008.1_24323001_2 - 5.4e-14 52.4 0.0 7.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001330008.1_24323001_2 - 1.3e-13 50.5 0.0 1.5e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.3 001330008.1_24323001_2 - 3e-12 46.4 0.0 9.8e-12 44.7 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.11 001330008.1_24323001_2 - 3.1e-08 33.4 0.1 5.1e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.13 001330008.1_24323001_2 - 0.003 16.6 0.1 0.0048 15.9 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.8 001330008.1_24323001_2 - 0.015 15.1 0.1 0.046 13.5 0.1 1.7 1 1 0 1 1 1 0 KR domain adh_short PF00106.23 001330008.1_24323001_2 - 0.07 12.4 0.1 0.26 10.6 0.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase TBCC PF07986.10 001330049.1_24323001_1 - 1.5e-37 127.8 0.0 2.4e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.3 001330049.1_24323001_1 - 1.1e-29 103.1 3.9 1.6e-29 102.6 3.9 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Reo_sigmaC PF04582.10 001330049.1_24323001_1 - 0.14 11.3 4.8 0.14 11.4 3.6 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein RRM_1 PF00076.20 001302605.1_35122001_1 - 1.2e-20 72.9 0.0 1.7e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.21 001302605.1_35122001_1 - 2.2e-08 33.7 3.1 4.3e-08 32.7 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.4 001302605.1_35122001_1 - 0.0014 18.2 2.0 0.0014 18.2 2.0 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.4 001302605.1_35122001_1 - 0.044 13.6 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Sar8_2 PF03058.12 144373.1_48422120_3 - 0.00036 20.9 0.0 0.00036 20.9 0.0 2.1 2 0 0 2 2 2 1 Sar8.2 family GRP PF07172.9 144373.1_48422120_3 - 0.0012 19.4 1.6 0.0058 17.2 0.0 2.1 2 0 0 2 2 2 1 Glycine rich protein family DUF3139 PF11337.6 144373.1_48422120_3 - 0.62 10.5 7.9 3.8 8.0 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Kunitz_legume PF00197.16 001301877.1_07122001_3 - 8.1e-24 84.4 0.0 1e-23 84.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor PPR_2 PF13041.4 001302520.1_35324001_1 - 4.1e-129 420.6 37.6 4.7e-18 65.0 0.1 14.1 1 1 12 14 14 14 14 PPR repeat family PPR_1 PF12854.5 001302520.1_35324001_1 - 7.6e-117 380.5 38.4 2e-12 46.4 0.1 14.6 15 0 0 15 15 15 14 PPR repeat PPR PF01535.18 001302520.1_35324001_1 - 1.5e-88 284.9 39.2 1.8e-09 37.0 0.1 15.3 15 0 0 15 15 15 14 PPR repeat PPR_3 PF13812.4 001302520.1_35324001_1 - 4.2e-56 186.8 16.4 2.3e-11 43.5 0.2 8.7 7 2 2 9 9 9 8 Pentatricopeptide repeat domain PPR_long PF17177.2 001302520.1_35324001_1 - 1.9e-22 79.6 0.0 6.3e-06 25.6 0.0 5.2 1 1 2 5 5 5 5 Pentacotripeptide-repeat region of PROPR MRP-S27 PF10037.7 001302520.1_35324001_1 - 2.7e-08 33.0 3.2 0.00062 18.7 0.1 4.3 2 2 1 4 4 4 2 Mitochondrial 28S ribosomal protein S27 ECSIT PF06239.9 001302520.1_35324001_1 - 0.00015 20.8 0.8 2.9 6.8 0.1 4.8 3 1 0 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway SPOB_a PF14689.4 001302520.1_35324001_1 - 0.002 17.6 0.1 22 4.7 0.0 5.7 8 0 0 8 8 8 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_14 PF13428.4 001302520.1_35324001_1 - 0.018 15.7 0.0 2.5e+02 2.8 0.0 5.9 7 1 1 8 8 8 0 Tetratricopeptide repeat Epimerase PF01370.19 001302522.1_35323001_1 - 4.9e-28 98.1 0.0 8.1e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001302522.1_35323001_1 - 5e-19 68.2 0.0 7.4e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.3 001302522.1_35323001_1 - 4e-17 62.5 0.0 7.6e-17 61.5 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 001302522.1_35323001_1 - 2.5e-15 56.7 0.0 4.2e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001302522.1_35323001_1 - 1.4e-13 50.5 0.0 1.5e-12 47.1 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.11 001302522.1_35323001_1 - 2.3e-10 40.3 0.0 3.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.8 001302522.1_35323001_1 - 6.3e-07 29.3 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.23 001302522.1_35323001_1 - 2.9e-05 23.5 0.0 0.00013 21.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.13 001302522.1_35323001_1 - 5.5e-05 22.3 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001302522.1_35323001_1 - 0.043 12.8 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Phlebovirus_NSM PF07246.9 001302522.1_35323001_1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CDI PF02234.17 001302514.1_35322001_2 - 0.0034 17.4 1.2 0.0079 16.3 0.3 2.0 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor CDI PF02234.17 001302514.1_35322001_3 - 0.34 11.0 1.3 0.68 10.1 1.3 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor NDUFA12 PF05071.14 001248156.1_24122001_2 - 2.1e-26 92.4 2.5 3.3e-26 91.8 2.5 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Pkinase PF00069.23 001248343.1_24122001_1 - 1.3e-43 149.2 0.0 1.6e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001248343.1_24122001_1 - 2.8e-37 128.3 0.0 3.9e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001248343.1_24122001_1 - 0.00085 19.2 0.0 0.0018 18.1 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.6 001248343.1_24122001_1 - 0.0036 16.8 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 YukC PF10140.7 001248343.1_24122001_1 - 0.019 13.7 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pox_ser-thr_kin PF05445.9 001248343.1_24122001_1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Auxin_inducible PF02519.12 001250178.1_24122001_3 - 2.1e-26 91.8 0.0 2.9e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Auxin responsive protein KAAG1 PF15354.4 001249989.1_24122001_1 - 0.013 15.9 0.2 0.025 15.0 0.2 1.4 1 0 0 1 1 1 0 Kidney-associated antigen 1 Ribosomal_L18A PF01775.15 001249989.1_24122001_3 - 3.1e-53 178.9 3.2 4.2e-53 178.4 3.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF4050 PF13259.4 001250809.1_24122001_3 - 7.8e-28 97.9 2.4 4.2e-14 53.1 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF4050) Glutaredoxin PF00462.22 001251229.1_24122001_1 - 2.3e-11 43.6 0.1 3.4e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Spermine_synth PF01564.15 001280782.1_14923001_3 - 4.8e-97 323.7 0.0 6.5e-97 323.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_25 PF13649.4 001280782.1_14923001_3 - 1.3e-05 25.7 0.0 3.7e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.9 001280782.1_14923001_3 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.12 001280782.1_14923001_3 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.10 001280782.1_14923001_3 - 0.12 12.9 0.0 0.45 11.1 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.4 001280782.1_14923001_3 - 0.13 13.2 0.0 0.26 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.19 001305713.1_14924001_2 - 7.8e-107 357.4 0.0 9.1e-107 357.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001305713.1_14924001_2 - 0.014 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase iPGM_N PF06415.11 001305713.1_14924001_2 - 0.014 14.7 0.0 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 BPG-independent PGAM N-terminus (iPGM_N) Mem_trans PF03547.16 001280744.1_14925001_3 - 2.2e-179 595.7 5.2 3.2e-179 595.2 5.2 1.2 1 0 0 1 1 1 1 Membrane transport protein DUF3474 PF11960.6 001309351.1_24523001_1 - 3.5e-47 159.7 0.0 5.8e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.22 001309351.1_24523001_1 - 3.4e-32 112.1 25.0 5.1e-32 111.6 25.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Exostosin PF03016.13 001319973.1_21624001_1 - 1.9e-90 303.0 0.0 2.4e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Pkinase PF00069.23 001317876.1_06623001_1 - 2.2e-70 236.9 0.0 2.9e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001317876.1_06623001_1 - 2.4e-33 115.4 0.0 3.5e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_60s PF00428.17 001317876.1_06623001_1 - 0.035 14.5 5.3 0.082 13.3 5.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein APH PF01636.21 001317876.1_06623001_1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001317876.1_06623001_1 - 0.082 12.3 0.3 0.2 11.1 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase FA_hydroxylase PF04116.11 001319925.1_27123001_3 - 1.5e-19 70.5 20.9 1.5e-19 70.5 20.9 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Methyltransf_11 PF08241.10 001308690.1_27122001_1 - 1e-08 35.6 0.0 2.7e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.4 001308690.1_27122001_1 - 1.1e-06 29.1 0.0 2.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001308690.1_27122001_1 - 4.4e-05 24.0 0.0 8.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001308690.1_27122001_1 - 5.1e-05 23.0 0.0 9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 001308690.1_27122001_1 - 0.071 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RIP PF00161.17 001308815.1_27123001_1 - 1.8e-31 109.1 0.0 2.2e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome inactivating protein Glyco_hydro_18 PF00704.26 001308815.1_27123001_1 - 0.031 13.9 0.1 0.061 12.9 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 18 FeThRed_A PF02941.13 001308773.1_27122001_3 - 2.6e-27 94.6 0.1 3.9e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase variable alpha chain 2OG-FeII_Oxy PF03171.18 001305727.1_14923001_1 - 1.4e-29 102.4 0.1 2.4e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001305727.1_14923001_1 - 7.7e-24 84.6 0.1 1.7e-23 83.5 0.1 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_16 PF00722.19 001329810.1_52822001_3 - 1e-52 178.0 0.1 1.3e-52 177.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 XET_C PF06955.10 001329810.1_52822001_3 - 2e-13 49.9 1.0 4.7e-13 48.7 1.0 1.6 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus zf-RING_2 PF13639.4 001308797.1_27122001_3 - 3.3e-13 49.5 6.5 5e-13 49.0 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.4 001308797.1_27122001_3 - 5.1e-08 32.6 3.3 7.5e-08 32.1 3.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.3 001308797.1_27122001_3 - 5.3e-08 32.3 1.6 5.3e-08 32.3 1.6 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001308797.1_27122001_3 - 8e-08 31.9 4.6 1.4e-07 31.1 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001308797.1_27122001_3 - 1.1e-07 31.9 8.1 3e-07 30.5 8.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001308797.1_27122001_3 - 2.9e-07 30.1 3.7 4.7e-07 29.4 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001308797.1_27122001_3 - 1.6e-06 27.7 2.8 3.4e-06 26.7 2.8 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 001308797.1_27122001_3 - 4.4e-06 26.5 0.2 9.1e-06 25.5 0.1 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.5 001308797.1_27122001_3 - 5.4e-06 26.2 3.5 1.1e-05 25.2 3.5 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.3 001308797.1_27122001_3 - 5.3e-05 22.6 4.2 8.9e-05 21.9 4.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.4 001308797.1_27122001_3 - 0.0003 20.5 2.8 0.00049 19.8 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.4 001308797.1_27122001_3 - 0.0016 18.2 3.5 0.011 15.5 0.8 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.4 001308797.1_27122001_3 - 0.0054 16.3 5.1 0.0083 15.7 5.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.5 001308797.1_27122001_3 - 0.0083 16.1 7.1 0.015 15.3 7.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.9 001308797.1_27122001_3 - 0.035 14.3 4.4 0.072 13.3 4.4 1.5 1 0 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.12 001308797.1_27122001_3 - 0.041 13.6 0.6 0.19 11.4 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Rtf2 PF04641.10 001308797.1_27122001_3 - 0.062 12.5 0.2 0.098 11.9 0.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3H2C3 PF17122.3 001308797.1_27122001_3 - 0.066 13.1 3.4 0.2 11.6 3.4 1.8 1 1 0 1 1 1 0 Zinc-finger zf-RING_9 PF13901.4 001308797.1_27122001_3 - 0.11 12.3 1.6 0.17 11.7 1.6 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.6 001308797.1_27122001_3 - 0.14 12.2 6.7 0.45 10.6 6.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.27 001308797.1_27122001_3 - 0.54 10.1 5.2 0.88 9.4 5.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.4 001308797.1_27122001_3 - 0.64 10.1 3.0 0.52 10.4 0.8 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Ferritin PF00210.22 001329818.1_52822001_1 - 2.3e-36 124.7 2.1 2.9e-36 124.4 2.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain FCH PF00611.21 001329818.1_52822001_1 - 0.006 16.7 0.2 0.016 15.3 0.1 1.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Rubrerythrin PF02915.15 001329818.1_52822001_1 - 0.012 15.9 3.3 0.016 15.5 2.9 1.5 1 1 0 1 1 1 0 Rubrerythrin Sucrose_synth PF00862.17 001329834.1_52825001_1 - 1.6e-283 940.9 0.0 2.2e-283 940.5 0.0 1.2 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001329834.1_52825001_1 - 7.3e-31 106.9 0.0 1.3e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001329834.1_52825001_1 - 1.4e-09 38.3 0.0 3.5e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001329834.1_52825001_1 - 8.8e-06 25.9 0.0 2.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.25 001329834.1_52825001_1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain HTH_CodY PF08222.9 001329834.1_52825001_1 - 0.16 11.4 0.0 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 CodY helix-turn-helix domain SRF-TF PF00319.16 001301398.1_06622001_1 - 3.3e-20 71.2 0.1 5e-20 70.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PLD_C PF12357.6 001309350.1_24526001_1 - 1.1e-29 102.0 0.0 1.9e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.20 001309350.1_24526001_1 - 4.1e-21 74.1 0.3 1.7e-10 40.5 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif C2 PF00168.28 001309350.1_24526001_1 - 1.4e-14 54.1 0.0 3.2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain PLDc_2 PF13091.4 001309350.1_24526001_1 - 1.5e-10 40.9 0.0 1.2e-06 28.3 0.1 3.3 2 1 0 2 2 2 2 PLD-like domain SRF-TF PF00319.16 001310131.1_21322001_1 - 4.8e-24 83.4 0.1 7.6e-24 82.8 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001310131.1_21322001_1 - 2.3e-17 62.8 5.9 4.3e-17 62.0 5.9 1.4 1 0 0 1 1 1 1 K-box region Aida_N PF08910.8 001310131.1_21322001_1 - 0.042 14.1 1.1 0.091 13.0 1.1 1.6 1 0 0 1 1 1 0 Aida N-terminus Herpes_BLRF2 PF05812.10 001310131.1_21322001_1 - 0.094 12.7 5.6 0.04 13.9 3.0 1.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein T3SS_LEE_assoc PF13327.4 001310131.1_21322001_1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system subunit UPF0184 PF03670.11 001310131.1_21322001_1 - 0.67 10.2 5.1 3.2 8.1 0.3 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) K-box PF01486.15 001279943.1_06622001_1 - 5.1e-31 106.6 17.0 5.1e-31 106.6 17.0 2.3 2 0 0 2 2 1 1 K-box region SRF-TF PF00319.16 001279943.1_06622001_1 - 1.6e-27 94.6 0.1 2.6e-27 93.9 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CCDC84 PF14968.4 001279943.1_06622001_1 - 0.00012 21.7 11.2 0.00016 21.3 11.2 1.2 1 0 0 1 1 1 1 Coiled coil protein 84 Plasmodium_Vir PF05795.9 001279943.1_06622001_1 - 0.039 13.2 7.9 0.047 13.0 7.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDHD PF02862.15 001279943.1_06622001_1 - 0.11 12.5 13.5 0.13 12.2 13.5 1.3 1 0 0 1 1 1 0 DDHD domain Erythro_esteras PF05139.12 001279943.1_06622001_1 - 0.11 12.1 10.7 0.15 11.7 10.7 1.2 1 0 0 1 1 1 0 Erythromycin esterase DUF342 PF03961.11 001279943.1_06622001_1 - 0.22 9.9 14.0 0.34 9.3 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TFIIA PF03153.11 001279943.1_06622001_1 - 0.27 11.0 24.6 0.33 10.8 24.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.7 001279943.1_06622001_1 - 0.29 9.2 19.6 0.3 9.2 19.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.3 001279943.1_06622001_1 - 0.59 7.0 19.7 0.74 6.7 19.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3584 PF12128.6 001279943.1_06622001_1 - 0.72 7.2 30.9 1 6.7 30.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.10 001279943.1_06622001_1 - 0.74 9.0 25.5 1.2 8.4 25.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.4 001279943.1_06622001_1 - 1.1 8.4 18.5 1.1 8.4 17.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LMBR1 PF04791.14 001279943.1_06622001_1 - 1.7 7.3 14.5 1.9 7.2 14.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1192 PF06698.9 001279943.1_06622001_1 - 1.8 8.6 10.0 0.18 11.7 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Het-C PF07217.9 001279943.1_06622001_1 - 2.6 6.3 12.8 3.8 5.8 12.8 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C ALMT PF11744.6 001279943.1_06622001_1 - 3.7 6.1 16.8 4.8 5.8 16.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF572 PF04502.11 001279943.1_06622001_1 - 5.7 6.3 21.2 7.7 5.8 21.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PNGaseA PF12222.6 001279943.1_06622001_1 - 6 5.5 11.9 7.6 5.1 11.9 1.2 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Asp-B-Hydro_N PF05279.9 001279943.1_06622001_1 - 7.8 6.3 14.8 11 5.8 14.8 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2360 PF10152.7 001279943.1_06622001_1 - 9.1 6.5 15.3 17 5.7 15.3 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3474 PF11960.6 001309353.1_24523001_1 - 2.6e-44 150.4 0.1 4e-44 149.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.22 001309353.1_24523001_1 - 1.1e-31 110.4 27.0 1.9e-31 109.7 27.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Ribosomal_L7Ae PF01248.24 001308764.1_27121001_1 - 1.8e-23 81.9 0.0 2.1e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.4 001308764.1_27121001_1 - 0.0071 16.3 0.0 0.0083 16.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DPBB_1 PF03330.16 001308764.1_27121001_1 - 0.15 12.3 0.2 8.5 6.6 0.1 2.1 1 1 0 2 2 2 0 Lytic transglycolase BTB_2 PF02214.20 001308764.1_27121001_1 - 0.16 12.2 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Pkinase PF00069.23 001280693.1_14924001_2 - 3.9e-53 180.4 0.0 4.3e-52 177.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280693.1_14924001_2 - 9.1e-31 106.9 0.0 5.9e-23 81.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.4 001280693.1_14924001_2 - 0.00072 18.8 0.0 0.0035 16.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001280693.1_14924001_2 - 0.00072 19.4 0.1 0.0026 17.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.12 001280693.1_14924001_2 - 0.024 13.9 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRF-TF PF00319.16 001308935.1_14922001_1 - 7.6e-25 86.0 0.1 1.3e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001308935.1_14922001_1 - 9.6e-22 76.9 6.0 2e-21 75.8 6.0 1.5 1 0 0 1 1 1 1 K-box region DASH_Dad3 PF08656.8 001308935.1_14922001_1 - 0.15 12.0 0.9 0.35 10.8 0.9 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad3 zf-Dof PF02701.13 001308763.1_27124001_3 - 6.5e-34 115.7 10.9 1.7e-33 114.4 10.9 1.7 1 0 0 1 1 1 1 Dof domain, zinc finger SUIM_assoc PF16619.3 001308763.1_27124001_3 - 0.044 13.7 7.9 0.15 12.0 7.9 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.11 001308763.1_27124001_3 - 7.4 6.3 19.5 7.2 6.4 8.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy PF03171.18 001329828.1_52823001_2 - 1.6e-22 79.7 0.0 2.5e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001329828.1_52823001_2 - 4.4e-14 53.1 0.0 7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Melibiase_2 PF16499.3 001280571.1_14924001_1 - 7e-94 314.5 0.6 1e-93 314.0 0.6 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.16 001280571.1_14924001_1 - 2.4e-06 26.6 0.1 4.7e-06 25.7 0.0 1.4 2 0 0 2 2 2 1 Melibiase Raffinose_syn PF05691.10 001280571.1_14924001_1 - 0.052 11.2 0.0 0.075 10.7 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 TCP PF03634.11 001319923.1_27123001_1 - 2.1e-42 145.2 4.1 4.4e-42 144.2 4.1 1.5 1 0 0 1 1 1 1 TCP family transcription factor HLH PF00010.24 001305838.1_01624001_2 - 2.3e-13 49.7 2.6 5.1e-13 48.6 2.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_S20p PF01649.16 001305838.1_01624001_2 - 0.015 15.8 3.8 0.032 14.7 3.8 1.5 1 0 0 1 1 1 0 Ribosomal protein S20 SpoIIIAH PF12685.5 001305838.1_01624001_2 - 1.5 8.5 5.0 2.4 7.8 5.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SRF-TF PF00319.16 001302865.1_06623001_1 - 9.1e-26 89.0 0.1 1.9e-25 87.9 0.1 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001302865.1_06623001_1 - 7.8e-25 86.8 7.4 1.7e-24 85.6 7.4 1.5 1 0 0 1 1 1 1 K-box region DUF3508 PF12018.6 001302865.1_06623001_1 - 0.034 13.5 0.3 0.094 12.1 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3508) Occludin_ELL PF07303.11 001302865.1_06623001_1 - 0.084 13.5 0.8 0.23 12.0 0.8 1.8 1 0 0 1 1 1 0 Occludin homology domain Glyco_hydro_77 PF02446.15 001329821.1_52825001_2 - 1.3e-145 485.7 0.0 1.7e-145 485.3 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase Amino_oxidase PF01593.22 001329162.1_16325001_2 - 7e-69 233.1 0.0 8.1e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001329162.1_16325001_2 - 1.5e-14 53.8 0.1 3.1e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001329162.1_16325001_2 - 7.2e-07 29.0 0.0 1.4e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.9 001329162.1_16325001_2 - 9.7e-05 21.2 0.0 0.0092 14.7 0.0 2.1 2 0 0 2 2 2 1 MCRA family HI0933_like PF03486.12 001329162.1_16325001_2 - 0.00052 18.7 0.2 0.00081 18.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.12 001329162.1_16325001_2 - 0.00053 19.2 0.0 0.0012 18.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.22 001329162.1_16325001_2 - 0.00086 18.4 0.2 0.0013 17.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.5 001329162.1_16325001_2 - 0.0011 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.17 001329162.1_16325001_2 - 0.0031 16.7 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.25 001329162.1_16325001_2 - 0.046 14.1 0.1 0.13 12.7 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.4 001329162.1_16325001_2 - 0.047 13.6 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.20 001329162.1_16325001_2 - 0.049 12.6 0.1 0.074 12.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.16 001329162.1_16325001_2 - 0.054 13.3 0.1 0.098 12.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.19 001329162.1_16325001_2 - 0.066 12.4 0.2 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NMT PF01233.17 001317422.1_24124001_2 - 2.3e-78 261.4 0.2 3.3e-78 260.9 0.2 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.13 001317422.1_24124001_2 - 1.3e-75 253.4 0.0 2e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.5 001317422.1_24124001_2 - 0.0013 18.7 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain K-box PF01486.15 001329164.1_16322001_1 - 4.6e-27 93.9 14.5 4.6e-27 93.9 14.5 1.6 2 0 0 2 2 2 1 K-box region SRF-TF PF00319.16 001329164.1_16322001_1 - 2e-26 91.0 0.3 3.2e-26 90.4 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF4890 PF16231.3 001329164.1_16322001_1 - 0.014 15.8 2.0 0.032 14.6 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) DUF342 PF03961.11 001329164.1_16322001_1 - 0.043 12.3 2.4 0.054 12.0 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.13 001329164.1_16322001_1 - 0.13 11.7 5.4 0.15 11.5 5.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GIT_CC PF16559.3 001329164.1_16322001_1 - 3.8 7.5 10.5 5.6 7.0 5.0 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Occludin_ELL PF07303.11 001329164.1_16322001_1 - 5.2 7.7 9.9 3.3 8.3 6.3 2.3 2 1 1 3 3 3 0 Occludin homology domain p450 PF00067.20 001329171.1_16324001_3 - 2.1e-82 277.2 0.0 2.6e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AP2 PF00847.18 001319974.1_21623001_2 - 5.3e-13 48.9 0.9 1.5e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 AP2 domain UFD1 PF03152.12 001289201.1_24123001_2 - 7.3e-81 269.6 0.1 9.4e-81 269.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Connexin PF00029.17 001289201.1_24123001_2 - 1.2 8.7 4.3 2.2 7.8 4.3 1.4 1 0 0 1 1 1 0 Connexin UDPGT PF00201.16 001329809.1_52824001_1 - 3e-25 88.8 0.0 1.2e-24 86.9 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Cerato-platanin PF07249.10 001329809.1_52824001_1 - 0.048 13.6 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Cerato-platanin MIOX PF05153.13 001302717.1_21622001_1 - 8.9e-125 415.1 3.3 1.1e-124 414.8 3.3 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.20 001302717.1_21622001_1 - 0.009 16.1 0.8 0.046 13.8 0.1 2.3 3 0 0 3 3 3 1 HD domain Maf1 PF09174.8 001302717.1_21622001_1 - 0.039 14.0 1.4 0.14 12.1 0.2 2.3 2 1 0 2 2 2 0 Maf1 regulator PTPLA PF04387.12 001302717.1_21622001_1 - 0.083 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA Bac_small_YrzI PF09501.8 001302717.1_21622001_1 - 0.25 11.4 1.9 0.74 9.9 1.9 1.8 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) NAM PF02365.13 001279906.1_06623001_1 - 4.2e-26 91.5 0.1 8.2e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein AP2 PF00847.18 001251547.1_24122001_2 - 1.6e-13 50.6 1.6 2.2e-13 50.1 1.6 1.2 1 0 0 1 1 1 1 AP2 domain 2OG-FeII_Oxy PF03171.18 001329823.1_52823001_2 - 7e-26 90.5 0.0 1.4e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001329823.1_52823001_2 - 4.4e-16 59.6 0.0 7.1e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TcpA PF05946.10 001329823.1_52823001_2 - 0.032 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA Actin PF00022.17 001280818.1_48023001_1 - 1.5e-148 494.6 0.0 5e-148 492.9 0.0 1.7 1 1 0 1 1 1 1 Actin 2OG-FeII_Oxy PF03171.18 001305711.1_14922001_1 - 1.2e-27 96.2 0.0 2.1e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001305711.1_14922001_1 - 9.3e-17 61.8 0.0 1.5e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ricin_B_lectin PF00652.20 001287474.1_14923001_2 - 1.3e-40 138.5 2.5 6.9e-23 81.2 1.4 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.4 001287474.1_14923001_2 - 5.1e-08 33.4 7.9 0.047 14.3 0.0 4.2 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like Methuselah_N PF06652.10 001287474.1_14923001_2 - 0.019 14.7 0.6 0.11 12.2 0.3 2.1 1 1 2 3 3 3 0 Methuselah N-terminus SRF-TF PF00319.16 001302870.1_06622001_1 - 1.1e-23 82.3 0.1 1.9e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001302870.1_06622001_1 - 6.9e-13 48.5 7.9 1.3e-12 47.6 7.9 1.4 1 0 0 1 1 1 1 K-box region DUF4618 PF15397.4 001302870.1_06622001_1 - 0.042 13.2 4.1 0.14 11.4 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) NB-LRR PF12061.6 001302870.1_06622001_1 - 0.056 12.2 0.1 0.07 11.9 0.1 1.1 1 0 0 1 1 1 0 Late blight resistance protein R1 HLH PF00010.24 001308887.1_14922001_1 - 7.5e-10 38.5 2.1 1e-09 38.1 0.4 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Med19 PF10278.7 001308887.1_14922001_1 - 0.0098 15.7 1.2 0.0098 15.7 1.2 1.5 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 PP2C PF00481.19 001317885.1_06623001_1 - 5.9e-62 209.5 0.1 8.4e-62 209.0 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001317885.1_06623001_1 - 2.9e-06 26.9 0.1 2e-05 24.2 0.0 2.2 2 1 0 2 2 2 1 Protein phosphatase 2C Peroxidase_2 PF01328.15 001317885.1_06623001_1 - 0.029 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Peroxidase, family 2 SRF-TF PF00319.16 001302723.1_21623001_3 - 8e-26 89.1 0.3 1.3e-25 88.4 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001302723.1_21623001_3 - 2.3e-21 75.6 8.5 4.4e-21 74.7 8.5 1.4 1 0 0 1 1 1 1 K-box region Glyco_tran_28_C PF04101.14 001302723.1_21623001_3 - 0.016 15.1 3.5 0.025 14.4 3.5 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF4156 PF13698.4 001302723.1_21623001_3 - 0.022 15.0 1.9 0.045 14.0 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) GIT_CC PF16559.3 001302723.1_21623001_3 - 2 8.4 9.5 1.6 8.7 1.5 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.4 001302723.1_21623001_3 - 4.1 7.3 13.8 11 5.9 13.8 1.7 1 1 0 1 1 1 0 FlxA-like protein CENP-H PF05837.10 001302723.1_21623001_3 - 4.2 7.7 10.7 0.96 9.7 5.5 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Pkinase PF00069.23 001282152.1_48023001_1 - 1.9e-73 247.0 0.1 2.4e-73 246.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001282152.1_48023001_1 - 1.1e-44 152.5 0.0 1.4e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001282152.1_48023001_1 - 1.2e-23 82.9 1.2 3.2e-23 81.5 1.2 1.8 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001282152.1_48023001_1 - 2.4e-09 36.8 0.0 7.2e-09 35.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001282152.1_48023001_1 - 0.0018 18.1 0.0 0.18 11.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.20 001282152.1_48023001_1 - 0.0057 16.1 0.3 0.013 15.0 0.3 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.12 001282152.1_48023001_1 - 0.0057 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.14 001282152.1_48023001_1 - 0.077 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC1 family E1-E2_ATPase PF00122.18 001305776.1_14926001_1 - 3.2e-52 176.9 2.4 5.4e-52 176.1 1.8 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.24 001305776.1_14926001_1 - 1.3e-30 107.1 0.0 2.6e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.4 001305776.1_14926001_1 - 0.0054 16.7 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.10 001305776.1_14926001_1 - 1.1 8.8 11.7 0.36 10.4 0.7 3.3 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Clostridium_P47 PF06597.9 001305776.1_14926001_2 - 5.7 5.4 8.3 7.9 4.9 8.3 1.1 1 0 0 1 1 1 0 Clostridium P-47 protein DUF3474 PF11960.6 001309354.1_24523001_1 - 1.4e-39 135.1 0.0 2.3e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.22 001309354.1_24523001_1 - 2.4e-34 119.2 26.7 3.4e-34 118.7 26.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase AP2 PF00847.18 001287229.1_48022001_1 - 1.1e-12 47.9 0.5 2.6e-12 46.7 0.5 1.7 1 0 0 1 1 1 1 AP2 domain SRF-TF PF00319.16 001301394.1_06622001_1 - 3.2e-24 84.0 0.2 5.3e-24 83.3 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001301394.1_06622001_1 - 3.3e-15 55.9 11.3 3.3e-15 55.9 11.3 1.6 2 0 0 2 2 2 1 K-box region CCDC85 PF10226.7 001301394.1_06622001_1 - 0.0015 18.1 2.1 0.0016 18.0 0.9 1.7 1 1 0 1 1 1 1 CCDC85 family ZapB PF06005.10 001301394.1_06622001_1 - 0.032 14.6 3.7 0.032 14.6 3.7 2.8 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.19 001301394.1_06622001_1 - 0.4 10.7 10.3 0.3 11.1 3.1 3.2 2 1 1 3 3 3 0 bZIP transcription factor DUF972 PF06156.11 001301394.1_06622001_1 - 0.41 11.1 3.7 0.47 11.0 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF2721 PF11026.6 001301394.1_06622001_1 - 1 9.1 4.6 7.1 6.4 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2721) APG6 PF04111.10 001301394.1_06622001_1 - 1.2 8.3 9.0 3.7 6.7 9.1 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.12 001301394.1_06622001_1 - 1.9 8.1 8.5 1.3 8.7 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_P2_GpE PF06528.10 001308883.1_14922001_2 - 0.46 9.9 2.2 0.35 10.3 0.5 1.6 1 1 1 2 2 2 0 Phage P2 GpE TFIIS_C PF01096.16 001308883.1_14922001_3 - 4.2e-15 55.2 9.5 2e-14 53.0 4.2 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.5 001308883.1_14922001_3 - 0.0036 17.1 7.2 0.036 13.9 1.5 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.6 001308883.1_14922001_3 - 0.27 10.8 3.8 0.58 9.8 0.1 2.5 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DUF3797 PF12677.5 001308883.1_14922001_3 - 0.65 9.8 7.1 0.36 10.6 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) DZR PF12773.5 001308883.1_14922001_3 - 1.2 9.1 8.5 3.6 7.5 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.23 001280808.1_48023001_1 - 6.9e-74 248.4 0.0 8.9e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280808.1_48023001_1 - 2.6e-44 151.3 0.0 3.3e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001280808.1_48023001_1 - 9.8e-24 83.2 0.8 2.6e-23 81.8 0.8 1.8 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001280808.1_48023001_1 - 1.5e-09 37.5 0.0 2.8e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.12 001280808.1_48023001_1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001280808.1_48023001_1 - 0.0023 17.7 0.0 0.17 11.7 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.20 001280808.1_48023001_1 - 0.0053 16.2 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family ABC1 PF03109.14 001280808.1_48023001_1 - 0.12 12.4 0.3 0.34 11.0 0.2 1.7 1 1 0 1 1 1 0 ABC1 family Pkinase PF00069.23 001279955.1_06623001_1 - 5.7e-74 248.7 0.0 8.3e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001279955.1_06623001_1 - 8.5e-35 120.1 0.0 1.2e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001279955.1_06623001_1 - 2.5e-05 23.6 0.5 3.8e-05 23.0 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001279955.1_06623001_1 - 9.7e-05 21.7 0.0 0.00028 20.1 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Tom22 PF04281.11 001279955.1_06623001_1 - 0.045 13.4 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 APH PF01636.21 001279955.1_06623001_1 - 0.13 12.1 0.8 0.47 10.2 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family HLH PF00010.24 001319919.1_27124001_1 - 1e-09 38.1 1.5 2.7e-09 36.7 1.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WRKY PF03106.13 001305747.1_14923001_1 - 3.5e-51 171.2 11.6 2.7e-25 88.3 1.6 2.3 2 0 0 2 2 2 2 WRKY DNA -binding domain CG-1 PF03859.14 001305747.1_14923001_1 - 0.017 14.8 0.4 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 CG-1 domain FLYWCH PF04500.14 001305747.1_14923001_1 - 0.092 12.7 5.3 0.17 11.9 0.1 2.7 2 1 0 2 2 2 0 FLYWCH zinc finger domain FAR1 PF03101.13 001305747.1_14923001_1 - 0.2 12.3 3.0 1.5 9.4 0.0 2.7 2 1 0 2 2 2 0 FAR1 DNA-binding domain peroxidase PF00141.21 001329814.1_52823001_2 - 1.1e-70 237.8 0.0 1.3e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase MIP PF00230.18 001289334.1_24123001_3 - 7.1e-80 267.8 10.4 8.5e-80 267.6 10.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein MARVEL PF01284.21 001289334.1_24123001_3 - 4.7 7.1 16.3 5.2 6.9 1.4 3.0 1 1 1 2 2 2 0 Membrane-associating domain SRF-TF PF00319.16 001329166.1_16322001_1 - 4.1e-25 86.9 0.3 7.5e-25 86.0 0.3 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001329166.1_16322001_1 - 5.3e-14 52.1 12.2 9.4e-14 51.2 12.2 1.4 1 0 0 1 1 1 1 K-box region PTS_IIA PF02255.14 001329166.1_16322001_1 - 0.032 14.1 1.2 0.058 13.3 0.4 1.8 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit YflT PF11181.6 001329166.1_16322001_1 - 0.043 14.2 0.5 0.085 13.2 0.5 1.5 1 0 0 1 1 1 0 Heat induced stress protein YflT PsbP PF01789.14 001329166.1_16322001_1 - 0.091 12.7 0.8 0.13 12.2 0.8 1.2 1 0 0 1 1 1 0 PsbP K-box PF01486.15 001302866.1_06622001_1 - 2.9e-28 97.7 8.2 2.9e-28 97.7 8.2 2.2 3 0 0 3 3 3 1 K-box region SRF-TF PF00319.16 001302866.1_06622001_1 - 2.7e-26 90.6 0.3 4.8e-26 89.9 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Proton_antipo_C PF01010.17 001302866.1_06622001_1 - 0.19 11.2 1.2 0.29 10.6 1.2 1.3 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Exonuc_VII_L PF02601.13 001302866.1_06622001_1 - 0.22 10.9 6.4 0.25 10.7 6.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mem_trans PF03547.16 001329838.1_52825001_2 - 2.2e-199 661.6 0.3 2.5e-199 661.4 0.3 1.0 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.23 001317868.1_06623001_1 - 6.4e-73 245.2 0.0 8e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001317868.1_06623001_1 - 2.4e-32 112.1 0.0 4.5e-32 111.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.21 001317868.1_06623001_1 - 0.0047 16.8 0.0 0.032 14.0 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.18 001317868.1_06623001_1 - 0.023 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.23 001279920.1_06624001_1 - 1.4e-57 195.0 0.0 1.8e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001279920.1_06624001_1 - 1.4e-35 122.8 0.0 1.8e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001279920.1_06624001_1 - 0.00026 20.3 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001279920.1_06624001_1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family HLH PF00010.24 001252870.2_24123001_2 - 6.8e-08 32.2 0.0 6.8e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3450 PF11932.6 001252870.2_24123001_2 - 0.0026 16.9 6.6 0.0048 16.1 6.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ZapB PF06005.10 001252870.2_24123001_2 - 0.0066 16.7 9.7 0.0066 16.7 9.7 2.4 3 0 0 3 3 3 1 Cell division protein ZapB APG6 PF04111.10 001252870.2_24123001_2 - 0.011 15.0 4.5 0.011 15.0 4.5 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.4 001252870.2_24123001_2 - 0.013 14.9 4.3 0.013 14.9 4.3 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 AAA_23 PF13476.4 001252870.2_24123001_2 - 0.017 15.5 0.2 0.017 15.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain DUF4140 PF13600.4 001252870.2_24123001_2 - 0.018 15.3 1.9 0.018 15.3 1.9 1.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.12 001252870.2_24123001_2 - 0.031 13.9 4.0 0.055 13.1 4.0 1.4 1 0 0 1 1 1 0 IncA protein KfrA_N PF11740.6 001252870.2_24123001_2 - 0.18 12.4 2.0 0.32 11.5 2.0 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term EMP24_GP25L PF01105.22 001252870.2_24123001_2 - 5.7 6.7 6.9 14 5.4 6.9 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD K-box PF01486.15 001305835.1_01622001_1 - 9.3e-28 96.1 6.8 1.7e-27 95.3 6.8 1.4 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001305835.1_01622001_1 - 6.9e-27 92.5 0.2 1.3e-26 91.7 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HMMR_N PF15905.3 001305835.1_01622001_1 - 0.0063 15.9 5.1 0.0096 15.3 5.1 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal FlxA PF14282.4 001305835.1_01622001_1 - 0.021 14.7 3.6 0.033 14.0 3.3 1.5 1 1 0 1 1 1 0 FlxA-like protein SRF-TF PF00319.16 001301379.1_06622001_1 - 3.7e-25 87.0 0.1 5.7e-25 86.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001301379.1_06622001_1 - 3e-17 62.5 7.8 5.1e-17 61.7 7.8 1.3 1 0 0 1 1 1 1 K-box region HALZ PF02183.16 001301379.1_06622001_1 - 0.014 15.4 0.5 0.014 15.4 0.5 2.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper DivIC PF04977.13 001301379.1_06622001_1 - 0.12 12.0 0.7 0.3 10.8 0.7 1.7 1 0 0 1 1 1 0 Septum formation initiator CCDC-167 PF15188.4 001301379.1_06622001_1 - 8.7 6.6 9.6 7 6.9 2.0 2.6 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 AUX_IAA PF02309.14 001280781.1_14924001_2 - 9e-92 307.1 0.1 1.2e-91 306.8 0.1 1.1 1 0 0 1 1 1 1 AUX/IAA family E1-E2_ATPase PF00122.18 001305723.1_14926001_1 - 8.3e-63 211.5 0.5 8.3e-63 211.5 0.5 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.24 001305723.1_14926001_1 - 5.1e-46 157.5 2.1 9.3e-46 156.6 2.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.24 001305723.1_14926001_1 - 9.8e-33 112.3 1.0 1.2e-11 44.7 0.0 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.10 001305723.1_14926001_1 - 0.00061 19.5 2.3 0.00061 19.5 2.3 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Rbsn PF11464.6 001305723.1_14926001_1 - 0.082 12.5 0.2 0.58 9.8 0.1 2.2 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Glyco_transf_29 PF00777.16 001309352.1_24524001_2 - 3e-35 121.8 2.9 6.3e-35 120.7 2.8 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) UDPG_MGDP_dh_N PF03721.12 001319971.1_21623001_1 - 8.4e-67 224.2 0.2 1.4e-66 223.5 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.13 001319971.1_21623001_1 - 3.5e-37 126.9 0.1 4.1e-36 123.4 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.17 001319971.1_21623001_1 - 2.3e-32 110.9 0.0 4.3e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.13 001319971.1_21623001_1 - 0.0045 17.0 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2OG-FeII_Oxy PF03171.18 001329817.1_52824001_2 - 3.3e-25 88.4 0.0 5.6e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001329817.1_52824001_2 - 2.2e-16 60.5 0.0 3.8e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Myb_CC_LHEQLE PF14379.4 001252993.2_24123001_3 - 4.7e-13 48.5 7.3 7.1e-13 47.9 7.3 1.3 1 0 0 1 1 1 1 MYB-CC type transfactor, LHEQLE motif Myb_DNA-binding PF00249.29 001252993.2_24123001_3 - 6.9e-08 32.4 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mem_trans PF03547.16 001329833.1_52826001_2 - 4.5e-194 644.1 2.6 6.2e-194 643.6 2.6 1.2 1 0 0 1 1 1 1 Membrane transport protein PTR2 PF00854.19 001288600.1_14924001_1 - 1.5e-120 402.5 8.6 2.5e-120 401.8 8.6 1.3 1 0 0 1 1 1 1 POT family BT1 PF03092.14 001288600.1_14924001_1 - 0.0029 15.8 1.4 0.78 7.7 0.0 2.8 3 0 0 3 3 3 2 BT1 family DUF1304 PF06993.10 001288600.1_14924001_1 - 0.0032 17.3 0.9 0.0032 17.3 0.9 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1304) DUF1772 PF08592.9 001288600.1_14924001_1 - 0.37 11.0 0.1 0.37 11.0 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) PsbR PF04725.10 001308795.1_27121001_1 - 1.3e-49 166.4 5.5 1.6e-49 166.1 5.5 1.1 1 0 0 1 1 1 1 Photosystem II 10 kDa polypeptide PsbR Glyco_hydro_16 PF00722.19 001329830.1_52823001_3 - 2.2e-54 183.5 0.2 2.8e-54 183.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 XET_C PF06955.10 001329830.1_52823001_3 - 6.1e-15 54.8 0.3 1.3e-14 53.7 0.3 1.5 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus UDPGT PF00201.16 001329837.1_52824001_2 - 1.8e-26 92.9 0.0 3.7e-26 91.9 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Cerato-platanin PF07249.10 001329837.1_52824001_2 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Cerato-platanin Abhydrolase_3 PF07859.11 001290219.1_14922001_1 - 1.9e-57 194.4 0.0 2.3e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.26 001290219.1_14922001_1 - 1e-07 31.2 0.4 3.1e-07 29.6 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.5 001290219.1_14922001_1 - 0.0011 17.8 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.7 001290219.1_14922001_1 - 0.0022 16.8 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.6 001290219.1_14922001_1 - 0.045 12.9 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Myb_DNA-binding PF00249.29 001309349.1_24522001_1 - 7.8e-35 118.7 3.9 1.6e-17 63.2 1.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001309349.1_24522001_1 - 7.7e-23 80.4 1.5 5.9e-14 51.9 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Pkinase PF00069.23 001317347.1_06623001_1 - 1.7e-70 237.3 0.0 2.3e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001317347.1_06623001_1 - 1.6e-32 112.7 0.0 2.4e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_3_Rpc31 PF11705.6 001317347.1_06623001_1 - 8.4e-05 22.8 7.8 0.00013 22.1 7.8 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 APH PF01636.21 001317347.1_06623001_1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001317347.1_06623001_1 - 0.093 12.2 0.6 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase 14-3-3 PF00244.18 001329820.1_52823001_3 - 5.5e-105 349.6 1.9 6.5e-105 349.4 1.9 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF2890 PF11081.6 001329820.1_52823001_3 - 0.12 12.3 0.3 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NAM PF02365.13 001279950.1_06623001_1 - 1.2e-28 99.7 0.4 2e-28 98.9 0.4 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein DUF4632 PF15451.4 001279950.1_06623001_1 - 0.005 16.8 0.8 4.2 7.4 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4632) NTP_transferase PF00483.21 001253259.1_24123001_1 - 3e-53 180.8 0.0 4.3e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001253259.1_24123001_1 - 3.9e-10 40.2 0.0 5.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001253259.1_24123001_1 - 1.2e-08 34.2 6.4 5.5e-07 28.9 1.1 3.4 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.4 001253259.1_24123001_1 - 0.0039 16.8 4.9 0.074 12.7 3.7 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.3 001253259.1_24123001_1 - 0.018 13.1 0.2 0.026 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.17 001253259.1_24123001_1 - 0.039 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.17 001253259.1_24123001_1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF257 PF03192.11 001253259.1_24123001_1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 14-3-3 PF00244.18 001329822.1_52822001_2 - 1.7e-97 325.2 2.4 1.9e-97 324.9 2.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.4 001329822.1_52822001_2 - 0.036 13.4 0.1 0.055 12.8 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Phage_TAC_4 PF08748.9 001329822.1_52822001_2 - 0.048 13.8 0.1 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 Phage tail assembly chaperone MFS_1 PF07690.14 001308933.1_14923001_1 - 6.9e-23 81.0 39.1 6.9e-23 81.0 39.1 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily SRF-TF PF00319.16 001302879.1_06622001_1 - 1.3e-26 91.7 0.1 2.2e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001302879.1_06622001_1 - 4.6e-24 84.3 7.5 1.3e-23 82.9 7.5 1.7 1 0 0 1 1 1 1 K-box region Prominin PF05478.9 001302879.1_06622001_1 - 0.053 11.3 1.7 0.072 10.9 1.7 1.1 1 0 0 1 1 1 0 Prominin Proteasome_A_N PF10584.7 001302879.1_06622001_1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature HAUS6_N PF14661.4 001302879.1_06622001_1 - 0.061 12.8 8.9 0.083 12.4 8.3 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.13 001302879.1_06622001_1 - 0.37 10.4 7.7 1 9.0 2.0 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF5082 PF16888.3 001302879.1_06622001_1 - 1.4 9.2 7.3 0.81 9.9 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF972 PF06156.11 001302879.1_06622001_1 - 1.4 9.4 10.5 0.27 11.8 5.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) FlaC_arch PF05377.9 001302879.1_06622001_1 - 1.8 8.9 7.0 5.8 7.3 0.9 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) EMP24_GP25L PF01105.22 001302879.1_06622001_1 - 4.1 7.2 6.0 13 5.6 5.9 1.9 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD APG6 PF04111.10 001302879.1_06622001_1 - 5.9 6.1 12.8 6.7 5.9 11.6 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 WRKY PF03106.13 001280681.1_14923001_1 - 3.2e-50 168.2 10.9 1.7e-26 92.2 1.9 2.7 2 0 0 2 2 2 2 WRKY DNA -binding domain 2OG-FeII_Oxy PF03171.18 001255140.1_24123001_1 - 2e-28 98.7 0.0 4.1e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001255140.1_24123001_1 - 9.1e-28 97.3 0.1 2.1e-27 96.1 0.1 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal NmrA PF05368.11 001309355.1_24523001_3 - 8.7e-53 179.1 0.0 1.1e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.4 001309355.1_24523001_3 - 8.2e-07 29.0 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.19 001309355.1_24523001_3 - 3.3e-06 26.6 0.1 7.2e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001309355.1_24523001_3 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.8 001309355.1_24523001_3 - 0.037 13.8 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.10 001309355.1_24523001_3 - 0.055 12.5 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein UDPGT PF00201.16 001329836.1_52824001_1 - 1e-25 90.4 0.0 2.2e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Cerato-platanin PF07249.10 001329836.1_52824001_1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Cerato-platanin NADH-u_ox-rdase PF10785.7 001308724.1_27121001_1 - 1.8e-25 89.3 0.2 2.2e-25 89.0 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF3316 PF11777.6 001308724.1_27121001_1 - 0.014 15.3 0.1 0.018 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) K-box PF01486.15 001301377.1_06622001_1 - 6.8e-26 90.2 11.7 6.8e-26 90.2 11.7 1.7 2 0 0 2 2 2 1 K-box region SRF-TF PF00319.16 001301377.1_06622001_1 - 1.6e-25 88.1 0.4 3e-25 87.3 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FYTT PF07078.9 001301377.1_06622001_1 - 0.064 12.5 0.4 0.064 12.5 0.4 1.5 2 0 0 2 2 2 0 Forty-two-three protein DUF2721 PF11026.6 001301377.1_06622001_1 - 0.12 12.2 0.4 4.4 7.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) IncA PF04156.12 001301377.1_06622001_1 - 1.4 8.5 14.1 0.77 9.4 11.9 1.6 1 1 0 1 1 1 0 IncA protein bZIP_1 PF00170.19 001317878.1_06623001_1 - 1e-12 47.8 17.2 1.8e-12 47.1 17.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001317878.1_06623001_1 - 6.4e-11 42.0 17.4 1e-10 41.4 17.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001317878.1_06623001_1 - 0.00063 20.1 10.4 0.00063 20.1 10.4 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor HAUS6_N PF14661.4 001317878.1_06623001_1 - 0.7 9.4 8.2 1.1 8.8 8.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.12 001317878.1_06623001_1 - 0.87 9.4 10.3 3.7 7.4 11.1 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HSP20 PF00011.19 001308676.1_27122001_1 - 6e-19 68.0 1.9 8.2e-19 67.5 1.9 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Mem_trans PF03547.16 001329825.1_52826001_1 - 1e-194 646.2 3.1 1.2e-194 645.9 3.1 1.1 1 0 0 1 1 1 1 Membrane transport protein Fasciclin PF02469.20 001319972.1_21623001_1 - 9.9e-20 70.9 0.8 1.4e-19 70.5 0.8 1.2 1 0 0 1 1 1 1 Fasciclin domain LPAM_1 PF08139.10 001319972.1_21623001_1 - 0.077 13.4 1.7 0.24 11.9 1.7 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DEC-1_N PF04625.11 001319972.1_21623001_1 - 6.1 5.6 15.9 4.7 6.0 6.2 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Pkinase PF00069.23 001279912.1_06624001_1 - 2.8e-58 197.2 0.0 3.6e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001279912.1_06624001_1 - 5.3e-36 124.1 0.0 6.9e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001279912.1_06624001_1 - 0.00019 20.7 0.0 0.00032 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001279912.1_06624001_1 - 0.056 13.2 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.20 001279912.1_06624001_1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family DUF2624 PF11116.6 001279912.1_06624001_1 - 0.15 12.8 0.0 0.31 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) FA_desaturase PF00487.22 001309357.1_24523001_1 - 7.4e-33 114.3 27.2 1.1e-32 113.7 27.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.6 001309357.1_24523001_1 - 1.3e-25 89.9 0.1 2.2e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) SRF-TF PF00319.16 001329168.1_16323001_1 - 1.2e-26 91.8 0.2 2.3e-26 90.9 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001329168.1_16323001_1 - 1.3e-26 92.5 4.1 2.5e-26 91.6 4.1 1.4 1 0 0 1 1 1 1 K-box region HMMR_N PF15905.3 001329168.1_16323001_1 - 0.022 14.1 3.1 0.034 13.5 3.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF2499 PF10693.7 001249682.2_24122001_1 - 3.9e-39 132.7 6.0 5.8e-39 132.1 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) Pollen_allerg_1 PF01357.19 001280756.1_14923001_2 - 2.6e-25 88.1 1.8 3.9e-25 87.6 1.8 1.3 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001280756.1_14923001_2 - 1.2e-22 79.9 0.0 2.3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase SRF-TF PF00319.16 001302882.1_06622001_1 - 7e-27 92.5 0.2 1.2e-26 91.8 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001302882.1_06622001_1 - 7.9e-22 77.1 7.4 7.9e-22 77.1 7.4 1.8 2 0 0 2 2 2 1 K-box region Jnk-SapK_ap_N PF09744.7 001302882.1_06622001_1 - 0.01 15.9 5.9 0.01 15.9 5.9 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Viral_env_E26 PF11050.6 001302882.1_06622001_1 - 0.026 13.8 3.8 0.029 13.6 0.6 2.3 1 1 2 3 3 3 0 Virus envelope protein E26 DUF2115 PF09888.7 001302882.1_06622001_1 - 1 9.7 7.2 0.23 11.8 2.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) TMF_DNA_bd PF12329.6 001302882.1_06622001_1 - 3.3 7.7 9.9 1.7 8.6 0.3 2.8 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Tryp_alpha_amyl PF00234.20 001308754.1_27122001_2 - 1.4e-07 31.7 17.3 4e-07 30.2 17.3 1.6 1 1 0 1 1 1 1 Protease inhibitor/seed storage/LTP family Gliadin PF13016.4 001308754.1_27122001_2 - 0.00054 20.2 17.7 0.00054 20.2 17.7 1.8 2 0 0 2 2 2 1 Cys-rich Gliadin N-terminal DUF3591 PF12157.6 001308754.1_27122001_2 - 0.021 13.3 0.5 0.027 13.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) IncA PF04156.12 001308754.1_27122001_2 - 2.1 8.0 4.9 8.3 6.0 0.1 2.0 2 0 0 2 2 2 0 IncA protein Glycos_transf_1 PF00534.18 001305731.1_14927001_1 - 2.7e-27 95.3 0.0 1.1e-26 93.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 S6PP PF05116.11 001305731.1_14927001_1 - 9.1e-18 64.6 0.0 1.8e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Glyco_trans_1_4 PF13692.4 001305731.1_14927001_1 - 1.4e-15 57.8 0.0 4.8e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Sucrose_synth PF00862.17 001305731.1_14927001_1 - 7.1e-11 41.0 0.0 2.1e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Sucrose synthase Glyco_trans_4_4 PF13579.4 001305731.1_14927001_1 - 2.6e-07 31.1 0.0 9.3e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.4 001305731.1_14927001_1 - 2.6e-06 27.4 0.1 2.3e-05 24.3 0.0 2.7 3 1 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.4 001305731.1_14927001_1 - 0.0014 18.9 0.0 0.0054 17.0 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 SAP PF02037.25 001305731.1_14927001_1 - 0.0029 17.2 0.2 0.0079 15.8 0.2 1.8 1 0 0 1 1 1 1 SAP domain DUF1752 PF08550.8 001305731.1_14927001_1 - 0.0037 16.9 3.4 0.0037 16.9 3.4 2.0 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1752) Vpu PF00558.17 001305731.1_14927001_1 - 0.85 9.3 6.9 4.7 6.9 2.5 3.4 2 1 1 3 3 3 0 Vpu protein Lycopene_cycl PF05834.10 001329179.1_16324001_2 - 2.3e-140 467.8 0.0 2.7e-140 467.6 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.12 001329179.1_16324001_2 - 5e-07 29.1 0.2 8.8e-05 21.7 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001329179.1_16324001_2 - 8.4e-05 21.9 0.1 0.00013 21.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.22 001329179.1_16324001_2 - 0.00041 19.4 0.2 0.0006 18.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.12 001329179.1_16324001_2 - 0.00097 18.0 1.0 0.0059 15.4 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.15 001329179.1_16324001_2 - 0.002 17.3 0.2 0.054 12.6 0.0 2.5 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.12 001329179.1_16324001_2 - 0.0024 16.5 0.1 0.0045 15.6 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein 2-Hacid_dh_C PF02826.17 001329179.1_16324001_2 - 0.093 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.4 001329179.1_16324001_2 - 0.093 11.8 0.4 0.26 10.3 0.4 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001329179.1_16324001_2 - 0.12 11.9 0.1 15 4.9 0.1 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.4 001329179.1_16324001_2 - 0.13 12.4 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.25 001329179.1_16324001_2 - 0.13 12.7 0.0 0.84 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001329179.1_16324001_2 - 0.16 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A WRKY PF03106.13 001280755.1_14922001_1 - 1.9e-26 92.0 3.7 3.5e-26 91.2 3.7 1.4 1 0 0 1 1 1 1 WRKY DNA -binding domain SRF-TF PF00319.16 001301385.1_06622001_1 - 5.6e-24 83.2 0.1 8.4e-24 82.7 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mem_trans PF03547.16 001329824.1_52825001_3 - 2.8e-198 657.9 1.4 3.3e-198 657.7 1.4 1.0 1 0 0 1 1 1 1 Membrane transport protein Mem_trans PF03547.16 001329816.1_52825001_1 - 4.2e-190 631.0 0.7 4.9e-190 630.8 0.7 1.0 1 0 0 1 1 1 1 Membrane transport protein SRF-TF PF00319.16 001301396.1_06622001_1 - 3.1e-25 87.3 0.1 5.2e-25 86.5 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001301396.1_06622001_1 - 2.6e-21 75.5 7.3 4.4e-21 74.7 7.3 1.4 1 0 0 1 1 1 1 K-box region S-methyl_trans PF02574.14 001255423.1_24123001_2 - 1.3e-78 264.4 0.0 1.5e-78 264.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase 2OG-FeII_Oxy PF03171.18 001329813.1_52823001_3 - 7.4e-28 96.9 0.0 1.2e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001329813.1_52823001_3 - 4.9e-15 56.2 0.0 9.5e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal FA_desaturase PF00487.22 001309356.1_24523001_1 - 2e-32 112.9 24.3 3e-32 112.3 24.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.6 001309356.1_24523001_1 - 4.1e-28 98.1 0.2 7.3e-28 97.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) K-box PF01486.15 001301401.1_06622001_1 - 1.1e-29 102.3 9.5 1.1e-29 102.3 9.5 2.0 2 0 0 2 2 2 1 K-box region SRF-TF PF00319.16 001301401.1_06622001_1 - 4.6e-25 86.7 1.2 8.4e-25 85.9 0.1 2.0 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Stn1 PF10451.7 001301401.1_06622001_1 - 0.00042 19.2 2.2 0.025 13.4 0.2 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 LEA_5 PF00477.15 001301401.1_06622001_1 - 0.045 14.1 0.1 0.084 13.2 0.1 1.5 1 0 0 1 1 1 0 Small hydrophilic plant seed protein KASH_CCD PF14662.4 001301401.1_06622001_1 - 0.06 13.1 11.1 1.4 8.6 3.6 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-H PF05837.10 001301401.1_06622001_1 - 0.25 11.7 5.3 3.5 7.9 0.1 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) SOGA PF11365.6 001301401.1_06622001_1 - 0.49 11.4 6.2 9.4 7.3 5.9 2.5 1 1 1 2 2 2 0 Protein SOGA bZIP_1 PF00170.19 001301401.1_06622001_1 - 1.8 8.6 5.3 1.7 8.7 0.8 2.7 1 1 0 2 2 2 0 bZIP transcription factor ZapB PF06005.10 001301401.1_06622001_1 - 6.3 7.2 12.1 5.9 7.3 1.5 2.8 1 1 1 2 2 2 0 Cell division protein ZapB DAGAT PF03982.11 001306044.1_27123001_2 - 7.3e-73 244.9 0.1 9.1e-73 244.6 0.1 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.19 001306044.1_27123001_2 - 0.011 15.2 0.1 0.021 14.3 0.1 1.5 1 0 0 1 1 1 0 Acyltransferase TRAPPC10 PF12584.6 001306044.1_27123001_2 - 0.078 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 NmrA PF05368.11 001309358.1_24523001_1 - 1.1e-48 165.7 0.0 1.8e-48 165.0 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.19 001309358.1_24523001_1 - 4.7e-08 32.7 0.0 9.7e-08 31.6 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.4 001309358.1_24523001_1 - 3.2e-07 30.3 0.0 4.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.3 001309358.1_24523001_1 - 2e-06 27.3 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.17 001309358.1_24523001_1 - 1.1e-05 24.4 0.1 1.7e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.8 001309358.1_24523001_1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.13 001309358.1_24523001_1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.23 001309358.1_24523001_1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase SRF-TF PF00319.16 001310130.1_21322001_1 - 4.2e-25 86.8 0.2 6.5e-25 86.2 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001310130.1_21322001_1 - 3.9e-16 58.9 6.6 1e-15 57.5 6.6 1.7 1 0 0 1 1 1 1 K-box region Thioredoxin_8 PF13905.4 001310130.1_21322001_1 - 0.013 15.7 0.1 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like CHAD PF05235.12 001310130.1_21322001_1 - 0.018 14.9 0.3 0.023 14.6 0.3 1.2 1 0 0 1 1 1 0 CHAD domain Speriolin_C PF15059.4 001310130.1_21322001_1 - 0.034 14.2 1.7 0.068 13.2 1.7 1.5 1 0 0 1 1 1 0 Speriolin C-terminus Phage_Gp19 PF09355.8 001310130.1_21322001_1 - 0.084 13.2 0.5 0.51 10.7 0.1 2.2 1 1 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Taeniidae_ag PF05596.9 001310130.1_21322001_1 - 0.091 12.6 0.7 0.22 11.4 0.2 1.9 2 0 0 2 2 2 0 Taeniidae antigen Herpes_BLRF2 PF05812.10 001310130.1_21322001_1 - 0.16 12.0 3.6 0.081 12.9 1.3 1.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein 2OG-FeII_Oxy PF03171.18 001329840.1_52823001_2 - 4.6e-23 81.5 0.0 1.1e-22 80.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001329840.1_52823001_2 - 3.4e-10 40.6 0.0 6.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal zf-Dof PF02701.13 001308810.1_27123001_2 - 4e-33 113.2 8.7 6.8e-33 112.5 8.7 1.3 1 0 0 1 1 1 1 Dof domain, zinc finger Chal_sti_synt_N PF00195.17 001318155.1_34423001_1 - 4.3e-125 415.4 0.1 6e-125 414.9 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.13 001318155.1_34423001_1 - 1.8e-72 242.2 0.0 3e-72 241.4 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.8 001318155.1_34423001_1 - 7.4e-08 32.3 0.1 1.6e-06 28.0 0.0 2.8 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.8 001318155.1_34423001_1 - 2.9e-06 26.9 0.1 6.9e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.10 001318155.1_34423001_1 - 1.3e-05 24.5 0.0 1.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Pkinase PF00069.23 001281285.1_53023001_1 - 1.6e-72 243.9 0.0 2e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001281285.1_53023001_1 - 4.5e-39 134.2 0.0 6.1e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001281285.1_53023001_1 - 1.7e-23 82.4 0.4 4.3e-23 81.1 0.4 1.6 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001281285.1_53023001_1 - 1.4e-09 37.6 0.0 3.3e-08 33.1 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001281285.1_53023001_1 - 0.0059 15.8 0.0 0.015 14.5 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001281285.1_53023001_1 - 0.023 14.5 0.0 0.083 12.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.9 001281285.1_53023001_1 - 0.035 13.0 0.0 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Baculo_LEF5_C PF11792.6 001281285.1_53023001_1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain RRM_1 PF00076.20 001302984.1_08321001_1 - 4.3e-23 80.8 0.0 5.6e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001302984.1_08321001_1 - 6.5e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif GRP PF07172.9 001302984.1_08321001_1 - 0.011 16.3 22.4 0.015 15.8 22.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family RRM_occluded PF16842.3 001302984.1_08321001_1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.4 001302984.1_08321001_1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PLD_C PF12357.6 001288898.1_12726001_2 - 1.7e-29 101.4 0.0 2.9e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.20 001288898.1_12726001_2 - 1.9e-18 65.6 0.2 1.1e-07 31.6 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif C2 PF00168.28 001288898.1_12726001_2 - 2.5e-15 56.5 0.0 6.2e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 C2 domain PLDc_2 PF13091.4 001288898.1_12726001_2 - 1.5e-09 37.7 0.1 7.4e-07 29.0 0.1 3.5 2 2 0 2 2 2 1 PLD-like domain MFS_2 PF13347.4 001281141.2_53024001_2 - 9.2e-14 50.7 10.2 9.2e-14 50.7 10.2 1.9 2 0 0 2 2 2 1 MFS/sugar transport protein DUF485 PF04341.10 001281141.2_53024001_2 - 0.77 9.6 0.0 0.77 9.6 0.0 3.5 5 0 0 5 5 5 0 Protein of unknown function, DUF485 Caveolin PF01146.15 001281141.2_53024001_2 - 3.5 7.5 5.4 22 4.8 0.2 2.6 2 0 0 2 2 2 0 Caveolin Response_reg PF00072.22 001303066.1_05526001_3 - 4e-21 75.2 0.0 6.8e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain UDPGT PF00201.16 001303066.1_05526001_3 - 0.011 14.4 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase CCT PF06203.12 001303066.1_05526001_3 - 0.021 14.8 6.5 0.044 13.7 6.5 1.6 1 0 0 1 1 1 0 CCT motif CCT_2 PF09425.8 001303066.1_05526001_3 - 1.5 8.6 5.7 2.6 7.9 5.7 1.4 1 0 0 1 1 1 0 Divergent CCT motif Ras PF00071.20 001303083.1_05522001_1 - 3.1e-51 173.1 0.0 3.6e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001303083.1_05522001_1 - 3.6e-24 85.2 0.0 5.7e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001303083.1_05522001_1 - 7.6e-05 22.1 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001303083.1_05522001_1 - 0.074 12.5 0.0 0.21 10.9 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain bZIP_1 PF00170.19 001303075.1_05524001_2 - 7.1e-14 51.5 16.2 1.5e-13 50.5 16.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001303075.1_05524001_2 - 2.9e-11 43.1 17.0 2.9e-11 43.1 17.0 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.15 001303075.1_05524001_2 - 0.0043 17.4 11.3 0.0043 17.4 11.3 2.8 3 0 0 3 3 3 1 bZIP Maf transcription factor DUF1329 PF07044.9 001303075.1_05524001_2 - 0.0098 15.1 2.6 0.018 14.2 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) FAM70 PF14967.4 001303075.1_05524001_2 - 2.5 7.3 6.3 4 6.7 6.3 1.2 1 0 0 1 1 1 0 FAM70 protein Pex14_N PF04695.11 001303075.1_05524001_2 - 3.3 8.3 16.2 0.07 13.7 8.1 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.1 001303075.1_05524001_2 - 7.1 6.7 10.4 7.9 6.6 1.6 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF4834 PF16118.3 001303075.1_05524001_3 - 0.18 12.6 0.0 0.3 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ATP-synt_C PF00137.19 001303085.1_05523001_1 - 5.4e-34 116.2 36.7 3.9e-20 71.8 13.6 2.6 2 0 0 2 2 2 2 ATP synthase subunit C Ras PF00071.20 001303087.1_05523001_1 - 2.9e-61 205.6 0.3 3.7e-61 205.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001303087.1_05523001_1 - 6.6e-34 116.6 0.1 9.6e-34 116.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001303087.1_05523001_1 - 1.3e-13 50.6 0.1 1.9e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001303087.1_05523001_1 - 9.3e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001303087.1_05523001_1 - 0.005 16.3 0.1 0.011 15.1 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001303087.1_05523001_1 - 0.0079 16.0 0.1 0.15 11.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001303087.1_05523001_1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001303087.1_05523001_1 - 0.021 14.2 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.4 001303087.1_05523001_1 - 0.098 12.9 0.2 0.18 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.4 001303087.1_05523001_1 - 0.12 12.3 0.1 0.56 10.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.4 001303087.1_05523001_1 - 0.14 11.7 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Robl_LC7 PF03259.15 001303087.1_05523001_3 - 0.22 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Roadblock/LC7 domain Bac_globin PF01152.19 001303089.1_05523001_2 - 2.5e-42 143.7 0.3 4.1e-42 143.0 0.3 1.3 1 0 0 1 1 1 1 Bacterial-like globin Ras PF00071.20 001303069.1_05523001_1 - 5.3e-66 221.1 0.2 6.6e-66 220.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001303069.1_05523001_1 - 1.4e-34 118.8 0.1 2.1e-34 118.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001303069.1_05523001_1 - 7.8e-15 54.6 0.1 1.1e-14 54.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001303069.1_05523001_1 - 2.9e-05 23.6 0.2 7.2e-05 22.3 0.1 1.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001303069.1_05523001_1 - 9.4e-05 22.3 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001303069.1_05523001_1 - 0.00014 21.2 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.14 001303069.1_05523001_1 - 0.00044 20.1 0.8 0.62 9.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SRPRB PF09439.8 001303069.1_05523001_1 - 0.061 12.6 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.4 001303069.1_05523001_1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ldh_1_C PF02866.16 001303077.1_05522001_1 - 3.4e-36 124.5 0.0 4.9e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.21 001303077.1_05522001_1 - 8.9e-35 119.7 0.6 1.5e-34 119.0 0.6 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.17 001303077.1_05522001_1 - 0.025 13.4 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glycos_transf_1 PF00534.18 001303068.1_05528001_3 - 5.3e-24 84.6 0.0 1.1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 S6PP PF05116.11 001303068.1_05528001_3 - 5.9e-14 52.1 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Glyco_trans_1_4 PF13692.4 001303068.1_05528001_3 - 1e-13 51.8 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sucrose_synth PF00862.17 001303068.1_05528001_3 - 1.1e-11 43.6 0.0 3.5e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 Sucrose synthase Glyco_trans_4_4 PF13579.4 001303068.1_05528001_3 - 0.0029 17.9 0.0 0.0093 16.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF1752 PF08550.8 001303068.1_05528001_3 - 0.0039 16.8 4.3 0.013 15.2 4.3 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_transf_4 PF13439.4 001303068.1_05528001_3 - 0.0046 16.8 0.2 0.061 13.2 0.0 2.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.4 001303068.1_05528001_3 - 0.12 12.7 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF3886 PF13025.4 001303068.1_05528001_3 - 1.5 8.9 8.9 3.9 7.6 8.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Globin PF00042.20 001303093.1_05522001_3 - 2.7e-18 66.4 0.0 3.8e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Globin Protoglobin PF11563.6 001303093.1_05522001_3 - 0.036 13.9 0.0 0.047 13.5 0.0 1.3 1 1 0 1 1 1 0 Protoglobin MIP PF00230.18 001303070.1_05522001_1 - 4.9e-83 278.2 10.7 5.8e-83 277.9 10.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein NTP_transferase PF00483.21 001303063.1_05524001_1 - 3.1e-77 259.4 0.0 4e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.22 001303063.1_05524001_1 - 0.017 14.7 1.9 0.017 14.7 1.9 2.1 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.5 001303063.1_05524001_1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain MIP PF00230.18 001303079.1_05522001_1 - 4.9e-82 274.9 11.9 5.6e-82 274.7 11.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein ANAPC5 PF12862.5 001303079.1_05522001_3 - 0.078 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Glyco_hydro_17 PF00332.16 001320012.1_05523001_2 - 5.2e-116 387.3 0.8 6e-116 387.1 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Globin PF00042.20 001303090.1_05523001_3 - 1.7e-21 76.7 1.0 3.4e-21 75.7 1.0 1.5 1 0 0 1 1 1 1 Globin Calreticulin PF00262.16 001303065.1_05524001_2 - 8.5e-80 268.2 19.9 4.1e-60 203.4 8.6 2.6 2 1 1 3 3 3 2 Calreticulin family CDC45 PF02724.12 001303065.1_05524001_2 - 0.0028 15.9 10.7 0.025 12.8 12.6 1.6 2 0 0 2 2 2 1 CDC45-like protein Globin PF00042.20 001303091.1_05522001_1 - 4.1e-17 62.6 1.5 5.7e-17 62.1 0.7 1.6 2 0 0 2 2 2 1 Globin Response_reg PF00072.22 001303071.1_05525001_1 - 2.6e-18 66.1 0.0 4.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain CCT PF06203.12 001303071.1_05525001_1 - 1.5e-17 63.2 10.3 2.5e-17 62.5 10.3 1.4 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.8 001303071.1_05525001_1 - 0.026 14.3 2.8 0.055 13.2 2.8 1.5 1 0 0 1 1 1 0 Divergent CCT motif IATP PF04568.10 001303071.1_05525001_1 - 1.4 9.2 3.9 1.8 8.9 0.9 2.8 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP MFS_2 PF13347.4 001303092.1_05524001_2 - 1.3e-09 37.0 3.6 1.3e-09 37.0 3.6 1.9 3 0 0 3 3 3 1 MFS/sugar transport protein ATP-synt_ab PF00006.23 001303073.1_05525001_1 - 7.3e-105 349.2 0.0 1e-104 348.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.3 001303073.1_05525001_1 - 5.5e-43 145.5 0.0 1.6e-42 144.0 0.0 1.8 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.21 001303073.1_05525001_1 - 1.3e-13 51.2 0.9 2.3e-13 50.3 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain EF1_GNE PF00736.17 001303067.1_05523001_3 - 1.3e-31 108.5 1.1 2.1e-31 107.8 1.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain SURF2 PF05477.9 001303067.1_05523001_3 - 0.038 13.4 2.5 0.052 12.9 2.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF3246 PF11596.6 001303067.1_05523001_3 - 0.074 12.4 0.4 0.1 11.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) WRKY PF03106.13 001301918.1_07122001_1 - 1e-24 86.5 2.2 1e-24 86.5 2.2 2.2 2 0 0 2 2 2 1 WRKY DNA -binding domain PP2 PF14299.4 001329231.1_48423001_3 - 4.3e-35 120.7 0.1 6.1e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 Phloem protein 2 PTR2 PF00854.19 001320124.1_48424001_2 - 1.1e-74 251.5 6.5 1.6e-74 251.0 6.5 1.2 1 0 0 1 1 1 1 POT family Methyltransf_2 PF00891.16 001319172.1_48423001_2 - 4.6e-90 300.7 0.0 7.4e-90 300.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.9 001319172.1_48423001_2 - 6.6e-16 57.9 0.1 1.2e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.4 001319172.1_48423001_2 - 0.00067 19.5 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.10 001319172.1_48423001_2 - 0.009 15.4 0.1 0.087 12.2 0.0 2.1 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase ANF_receptor PF01094.26 001320992.1_48427001_3 - 2.1e-80 270.3 0.0 2.8e-80 269.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001320992.1_48427001_3 - 2.4e-33 114.9 0.3 4.4e-33 114.1 0.3 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.18 001320992.1_48427001_3 - 5.1e-19 68.5 0.0 1.1e-18 67.4 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.4 001320992.1_48427001_3 - 3e-16 59.9 0.0 4.5e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Lig_chan-Glu_bd PF10613.7 001320992.1_48427001_3 - 7.3e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site MIP PF00230.18 001251871.2_48423001_3 - 5.6e-37 127.5 15.8 7.6e-37 127.1 15.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein ODV-E18 PF10717.7 001251871.2_48423001_3 - 0.45 10.3 5.8 0.21 11.3 2.5 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Fig1 PF12351.6 001251871.2_48423001_3 - 6 6.6 14.6 8.1 6.2 11.6 2.2 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Vma12 PF11712.6 001251871.2_48423001_3 - 7.4 6.5 6.7 2.6 8.0 1.3 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RPE65 PF03055.13 001246909.2_48424001_3 - 1.2e-119 400.1 0.0 1.7e-119 399.6 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Sucrose_synth PF00862.17 001313910.1_48426001_1 - 2.3e-278 923.9 0.0 3.5e-278 923.3 0.0 1.3 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001313910.1_48426001_1 - 1.1e-33 116.1 0.1 2.7e-33 114.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001313910.1_48426001_1 - 1.9e-12 47.6 0.0 5.1e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001313910.1_48426001_1 - 7.5e-06 26.1 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_CodY PF08222.9 001313910.1_48426001_1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain eIF-1a PF01176.17 001347319.1_48422001_3 - 3.3e-21 74.7 0.1 4.7e-21 74.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Epimerase PF01370.19 001279174.2_48424001_1 - 1.8e-05 24.2 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TPT PF03151.14 001308011.1_48424001_1 - 3.4e-110 367.8 20.0 4.2e-110 367.5 20.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.18 001308011.1_48424001_1 - 4.4e-10 39.7 27.0 6.4e-07 29.5 7.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.9 001308011.1_48424001_1 - 0.8 8.7 20.0 0.038 13.1 12.3 1.9 1 1 1 2 2 2 0 UAA transporter family DUF2178 PF09946.7 001308011.1_48424001_1 - 2.5 8.1 5.7 0.47 10.5 0.5 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) Glyco_tranf_2_3 PF13641.4 001329781.1_48426001_1 - 1.6e-24 87.0 0.0 2.2e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.4 001329781.1_48426001_1 - 1.4e-20 74.0 0.5 1.4e-20 74.0 0.5 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.24 001329781.1_48426001_1 - 1.2e-12 47.8 0.0 2.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.4 001329781.1_48426001_1 - 6.5e-11 41.9 0.0 1.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Histidinol_dh PF00815.18 001321752.1_48424001_3 - 8.4e-160 532.1 0.2 9.8e-160 531.9 0.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase RINGv PF12906.5 001329130.1_48423001_1 - 1.6e-10 40.8 10.2 2.9e-10 40.0 10.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.4 001329130.1_48423001_1 - 0.027 14.6 6.7 0.071 13.3 6.7 1.8 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.5 001329130.1_48423001_1 - 0.099 12.8 5.9 0.26 11.5 5.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.9 001329130.1_48423001_1 - 0.26 11.5 7.6 0.91 9.8 7.5 2.1 1 1 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.23 001329130.1_48423001_1 - 0.87 9.4 5.0 4.7 7.0 5.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_ab PF00006.23 001247358.3_48425001_2 - 4.1e-107 356.5 0.0 5.6e-107 356.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.3 001247358.3_48425001_2 - 6.3e-41 138.9 0.0 1.1e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.21 001247358.3_48425001_2 - 7.5e-14 51.9 1.0 1.5e-13 50.9 1.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Doppel PF11466.6 001247358.3_48425001_2 - 0.43 10.2 2.3 0.91 9.1 2.3 1.5 1 0 0 1 1 1 0 Prion-like protein Doppel DUF4005 PF13178.4 001324079.1_48424001_1 - 7.6e-07 29.6 11.0 7.6e-07 29.6 11.0 3.2 3 2 0 3 3 3 1 Protein of unknown function (DUF4005) IQ PF00612.25 001324079.1_48424001_1 - 2e-06 27.0 1.1 5.7e-06 25.5 1.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-RING_2 PF13639.4 001321456.1_48423001_3 - 5.9e-11 42.3 14.0 1.1e-10 41.4 14.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001321456.1_48423001_3 - 3.7e-08 32.8 6.6 7.5e-08 31.8 6.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.5 001321456.1_48423001_3 - 0.0014 18.7 12.4 0.0047 17.1 12.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.4 001321456.1_48423001_3 - 0.0017 18.0 13.6 0.0032 17.2 13.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001321456.1_48423001_3 - 0.013 15.2 11.6 0.026 14.3 11.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.6 001321456.1_48423001_3 - 0.031 14.3 10.5 0.72 9.9 10.5 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.23 001321456.1_48423001_3 - 0.047 13.4 12.1 0.099 12.4 12.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001321456.1_48423001_3 - 0.88 9.4 10.4 1.6 8.6 10.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.27 001321456.1_48423001_3 - 2.6 7.9 11.1 5.5 6.8 11.1 1.6 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.23 001328539.1_48423001_2 - 7.6e-12 45.0 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.12 001328539.1_48423001_2 - 2.5e-08 33.4 0.0 1.2e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.15 001328539.1_48423001_2 - 5.5e-08 32.3 0.0 8e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001328539.1_48423001_2 - 2e-06 27.8 0.0 0.00075 19.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.20 001328539.1_48423001_2 - 1.1e-05 25.0 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.18 001328539.1_48423001_2 - 0.0028 17.1 0.0 0.0061 16.0 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.18 001328539.1_48423001_2 - 0.0034 16.6 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase WaaY PF06176.9 001328539.1_48423001_2 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) bHLH-MYC_N PF14215.4 001302525.1_35325001_1 - 6.8e-55 185.8 0.1 1.6e-54 184.6 0.1 1.7 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 001302525.1_35325001_1 - 4.7e-12 45.5 0.1 1.2e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain U3_snoRNA_assoc PF08297.9 001302525.1_35325001_1 - 3.9 8.1 5.9 0.46 11.1 0.8 2.1 2 0 0 2 2 2 0 U3 snoRNA associated Chal_sti_synt_N PF00195.17 001319862.1_35323001_1 - 1.9e-126 419.8 0.0 2.7e-126 419.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.13 001319862.1_35323001_1 - 3.1e-72 241.4 0.0 5.5e-72 240.6 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.8 001319862.1_35323001_1 - 3.3e-07 29.9 0.0 3.1e-06 26.8 0.1 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.10 001319862.1_35323001_1 - 7.2e-07 28.6 0.0 9.5e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.8 001319862.1_35323001_1 - 7.9e-07 29.0 0.2 6.4e-06 26.1 0.1 2.4 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Histone PF00125.22 001302521.1_35323001_1 - 8.6e-35 119.9 4.3 3.4e-34 117.9 4.3 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001302521.1_35323001_1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.21 001302521.1_35323001_1 - 0.054 13.7 0.1 0.09 12.9 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Alpha-amylase_C PF02806.16 001302849.1_34427001_1 - 1.1e-25 89.8 0.1 3.2e-25 88.3 0.1 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.16 001302849.1_34427001_1 - 6.8e-22 77.5 1.8 1e-21 76.9 0.2 2.2 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.22 001302849.1_34427001_1 - 4.7e-13 49.3 2.6 4.8e-10 39.4 2.6 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain NAM PF02365.13 001317128.1_53022001_1 - 1.8e-27 95.8 0.5 2.8e-27 95.2 0.5 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein Cupin_1 PF00190.20 001281015.1_53022001_3 - 5.4e-48 162.3 2.3 7e-48 161.9 2.3 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.9 001281015.1_53022001_3 - 2.6e-09 36.5 0.2 2.8e-08 33.2 0.1 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_7 PF12973.5 001281015.1_53022001_3 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 ChrR Cupin-like domain HAD_2 PF13419.4 001281217.1_53023001_2 - 4.5e-12 46.3 0.0 7.3e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.24 001281217.1_53023001_2 - 4.2e-06 27.1 0.0 0.09 12.9 0.0 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.4 001281217.1_53023001_2 - 1.1e-05 25.3 0.0 3.4e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.5 001281217.1_53023001_2 - 0.0074 16.0 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 1 Acid Phosphatase Pec_lyase_C PF00544.17 001303072.1_53023001_2 - 6.5e-23 81.3 3.5 4.5e-22 78.5 3.5 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.4 001303072.1_53023001_2 - 0.00014 21.6 8.6 0.00076 19.2 7.8 2.5 2 1 0 2 2 2 1 Right handed beta helix region AP2 PF00847.18 001280952.1_53025001_2 - 2.4e-19 69.2 9.7 2.2e-09 37.3 0.7 2.8 2 0 0 2 2 2 2 AP2 domain Voltage_CLC PF00654.18 001280981.1_53026001_1 - 2.3e-68 230.9 22.9 2.3e-68 230.9 22.9 1.6 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.26 001280981.1_53026001_1 - 3e-09 37.1 0.4 1.1e-05 25.6 0.2 2.5 2 0 0 2 2 2 2 CBS domain SRF-TF PF00319.16 001280946.1_53022001_3 - 3.4e-23 80.7 0.1 6.9e-23 79.7 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001280946.1_53022001_3 - 2.6e-18 65.8 8.7 4.2e-18 65.2 8.7 1.3 1 0 0 1 1 1 1 K-box region APG6 PF04111.10 001280946.1_53022001_3 - 0.0017 17.6 0.6 0.0023 17.2 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 HALZ PF02183.16 001280946.1_53022001_3 - 0.013 15.5 1.1 0.013 15.5 1.1 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.11 001280946.1_53022001_3 - 0.18 12.3 8.0 1.7 9.2 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SRF-TF PF00319.16 001302729.1_21623001_1 - 7.7e-27 92.4 1.7 1.7e-26 91.3 0.4 2.2 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001302729.1_21623001_1 - 7.8e-22 77.1 10.7 1.8e-21 76.0 10.7 1.5 1 0 0 1 1 1 1 K-box region Focal_AT PF03623.11 001302729.1_21623001_1 - 0.22 11.3 4.0 6.3 6.6 0.4 2.3 2 0 0 2 2 2 0 Focal adhesion targeting region GIT_CC PF16559.3 001302729.1_21623001_1 - 0.58 10.1 6.0 0.84 9.6 2.3 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cellulose_synt PF03552.12 001302716.1_21627001_3 - 0 1334.6 0.0 0 1333.8 0.0 1.4 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001302716.1_21627001_3 - 3e-16 59.2 6.4 7.1e-16 58.0 6.4 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001302716.1_21627001_3 - 1.2e-06 28.4 0.4 1.2e-06 28.4 0.4 3.3 4 0 0 4 4 4 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001302716.1_21627001_3 - 0.00026 20.5 7.2 0.00076 19.0 7.2 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Glyco_tranf_2_3 PF13641.4 001302716.1_21627001_3 - 0.089 12.5 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DoxX_2 PF13564.4 001302716.1_21627001_3 - 0.28 11.2 3.4 4.6 7.3 0.3 2.6 2 0 0 2 2 2 0 DoxX-like family Cellulose_synt PF03552.12 001302739.1_21628001_3 - 0 1377.1 0.0 0 1376.8 0.0 1.1 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001302739.1_21628001_3 - 3e-39 132.9 6.8 5.6e-39 132.0 6.8 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001302739.1_21628001_3 - 2.2e-08 34.1 0.3 2.2e-08 34.1 0.3 2.8 4 0 0 4 4 4 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001302739.1_21628001_3 - 7.3e-05 22.3 11.5 0.00014 21.4 11.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Glyco_tranf_2_3 PF13641.4 001302739.1_21628001_3 - 0.023 14.4 0.0 0.31 10.8 0.0 2.4 3 0 0 3 3 3 0 Glycosyltransferase like family 2 FYVE_2 PF02318.14 001302739.1_21628001_3 - 0.025 14.7 1.8 0.058 13.5 1.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.4 001302739.1_21628001_3 - 1.1 9.1 12.8 5.3 6.9 11.7 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Tubulin PF00091.23 001302733.1_21624001_2 - 1e-69 234.6 0.0 1.6e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001302733.1_21624001_2 - 3.1e-40 137.2 0.3 4.6e-40 136.6 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001302733.1_21624001_2 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.4 001302733.1_21624001_2 - 0.0013 17.9 0.1 0.0035 16.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.4 001302733.1_21624001_2 - 0.0016 18.0 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain CAP_N PF01213.17 001302733.1_21624001_2 - 0.12 11.7 8.5 0.21 10.9 8.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Astro_capsid_p PF12226.6 001302733.1_21624001_2 - 0.41 9.6 4.3 0.62 9.0 4.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PRIMA1 PF16101.3 001302733.1_21624001_2 - 0.45 10.4 8.9 0.87 9.5 8.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.9 001302733.1_21624001_2 - 1.7 8.5 8.4 1.8 8.4 7.0 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator SRF-TF PF00319.16 001302708.1_21622001_1 - 2.9e-26 90.6 0.3 5e-26 89.8 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001302708.1_21622001_1 - 7.9e-16 57.9 12.6 1.5e-15 57.0 12.6 1.5 1 0 0 1 1 1 1 K-box region CAMP_factor PF07373.9 001302708.1_21622001_1 - 0.11 11.9 3.1 0.13 11.7 0.8 1.9 2 0 0 2 2 2 0 CAMP factor (Cfa) PRR20 PF15708.3 001302708.1_21622001_1 - 0.16 11.8 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 Proline-rich protein family 20 DUF1192 PF06698.9 001302708.1_21622001_1 - 0.24 11.4 3.2 5.1 7.1 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) APG6 PF04111.10 001302708.1_21622001_1 - 0.28 10.4 7.0 0.42 9.8 7.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 XhlA PF10779.7 001302708.1_21622001_1 - 0.51 10.4 4.0 0.81 9.8 1.5 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Osmo_CC PF08946.8 001302708.1_21622001_1 - 1.2 9.3 4.6 2.7 8.2 1.6 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil ZapB PF06005.10 001302708.1_21622001_1 - 2.2 8.7 14.1 0.19 12.0 3.4 2.5 1 1 1 2 2 2 0 Cell division protein ZapB SlyX PF04102.10 001302708.1_21622001_1 - 7.4 7.1 7.0 2.9 8.5 1.0 2.5 1 1 1 2 2 2 0 SlyX AKNA PF12443.6 001302708.1_21622001_1 - 8.6 6.9 10.9 1.4 9.5 4.7 2.7 1 1 2 3 3 3 0 AT-hook-containing transcription factor DivIC PF04977.13 001302708.1_21622001_1 - 9.3 6.0 9.1 0.65 9.7 1.2 2.9 2 1 1 3 3 3 0 Septum formation initiator BES1_N PF05687.11 001319975.1_21622001_1 - 3.3e-65 219.0 0.4 3.3e-65 219.0 0.4 2.6 2 1 1 3 3 3 1 BES1/BZR1 plant transcription factor, N-terminal K-box PF01486.15 001302720.1_21623001_1 - 1.8e-27 95.3 6.1 3.6e-27 94.3 6.1 1.5 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001302720.1_21623001_1 - 9.9e-27 92.0 0.2 1.9e-26 91.1 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FAM209 PF15206.4 001302720.1_21623001_1 - 0.061 13.0 0.4 0.47 10.1 0.2 2.2 1 1 1 2 2 2 0 FAM209 family GIT_CC PF16559.3 001302720.1_21623001_1 - 0.5 10.3 6.6 0.95 9.4 1.9 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Myb_DNA-binding PF00249.29 001302722.1_21622001_1 - 2.9e-37 126.5 1.9 7.6e-18 64.3 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001302722.1_21622001_1 - 1.1e-22 79.9 0.1 3.8e-14 52.5 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001302722.1_21622001_1 - 0.00035 20.4 0.0 0.21 11.5 0.0 2.3 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.6 001302722.1_21622001_1 - 0.054 13.4 0.4 0.19 11.7 0.4 2.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SRF-TF PF00319.16 001302727.1_21622001_2 - 2.1e-24 84.6 0.1 4.5e-24 83.5 0.1 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001302727.1_21622001_2 - 3.4e-17 62.3 8.3 6.9e-17 61.3 8.3 1.4 1 0 0 1 1 1 1 K-box region HALZ PF02183.16 001302727.1_21622001_2 - 0.027 14.5 2.8 0.027 14.5 2.8 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.13 001302727.1_21622001_2 - 0.46 10.2 3.6 0.71 9.6 0.7 2.4 2 0 0 2 2 2 0 Septum formation initiator Homeobox PF00046.27 001302738.1_21622001_1 - 2.2e-19 68.9 3.9 3.5e-19 68.2 1.8 2.4 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.9 001302738.1_21622001_1 - 0.026 14.3 0.2 0.076 12.8 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF4471 PF14740.4 001302738.1_21622001_1 - 0.032 13.3 7.6 0.2 10.6 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) CbtA PF09490.8 001302738.1_21622001_1 - 0.56 9.8 4.7 0.81 9.3 4.7 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF444 PF04285.10 001302738.1_21622001_1 - 2.9 6.7 8.7 0.4 9.6 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF444) DUF4638 PF15472.4 001302738.1_21622001_1 - 3.6 7.2 9.0 0.5 10.0 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) SARAF PF06682.10 001302738.1_21622001_1 - 4 6.9 11.0 0.4 10.2 3.5 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis FAM76 PF16046.3 001302738.1_21622001_1 - 4.1 6.5 16.3 0.21 10.8 5.9 2.1 2 0 0 2 2 2 0 FAM76 protein Tubulin PF00091.23 001302731.1_21624001_3 - 1.9e-68 230.5 0.0 2.5e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001302731.1_21624001_3 - 1.1e-50 171.0 0.1 1.8e-50 170.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001302731.1_21624001_3 - 0.0045 16.6 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Thioredoxin PF00085.18 001302721.1_21621001_1 - 4.1e-32 110.1 0.2 4.8e-32 109.9 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.4 001302721.1_21621001_1 - 2.2e-06 27.9 0.2 6.3e-05 23.3 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001302721.1_21621001_1 - 1.7e-05 24.9 0.0 0.00017 21.7 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.4 001302721.1_21621001_1 - 3.6e-05 23.7 0.2 6.7e-05 22.9 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.4 001302721.1_21621001_1 - 8.6e-05 22.2 0.0 0.0001 22.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.19 001302721.1_21621001_1 - 0.00013 21.7 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.14 001302721.1_21621001_1 - 0.00036 19.4 0.0 0.00042 19.2 0.0 1.0 1 0 0 1 1 1 1 Phosducin OST3_OST6 PF04756.11 001302721.1_21621001_1 - 0.00037 19.8 0.0 0.00043 19.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.8 001302721.1_21621001_1 - 0.0014 18.2 0.2 0.0069 15.9 0.2 1.9 1 1 0 1 1 1 1 Redoxin HyaE PF07449.9 001302721.1_21621001_1 - 0.0027 17.5 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DIM1 PF02966.14 001302721.1_21621001_1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Cation_efflux PF01545.19 001302735.1_21624001_2 - 3.6e-48 163.8 4.1 4.7e-48 163.4 4.1 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.20 001302735.1_21624001_2 - 0.0044 16.1 6.9 0.0079 15.3 6.9 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Metal_resist PF13801.4 001302735.1_21624001_2 - 0.048 13.7 0.7 0.11 12.5 0.7 1.6 1 0 0 1 1 1 0 Heavy-metal resistance DUF1510 PF07423.9 001302735.1_21624001_2 - 0.11 11.8 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Tubulin PF00091.23 001302709.1_21624001_3 - 3.3e-69 232.9 0.0 5e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001302709.1_21624001_3 - 1e-40 138.7 0.3 1.5e-40 138.2 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.4 001302709.1_21624001_3 - 0.00098 18.3 0.1 0.0027 16.8 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Misat_Tub_SegII PF10644.7 001302709.1_21624001_3 - 0.0015 18.7 0.0 0.0041 17.3 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001302709.1_21624001_3 - 0.0017 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Cellulose_synt PF03552.12 001302736.1_21627001_1 - 0 1369.8 0.0 0 1369.5 0.0 1.0 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001302736.1_21627001_1 - 4.5e-35 119.5 9.7 9.1e-35 118.5 9.7 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001302736.1_21627001_1 - 7e-07 29.2 0.7 7e-07 29.2 0.7 3.3 5 0 0 5 5 5 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001302736.1_21627001_1 - 0.0013 18.2 13.7 0.0013 18.2 13.7 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Glyco_tranf_2_3 PF13641.4 001302736.1_21627001_1 - 0.016 15.0 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Tubulin PF00091.23 001302737.1_21624001_1 - 9.3e-70 234.7 0.0 1.4e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001302737.1_21624001_1 - 5e-40 136.5 0.2 7.4e-40 136.0 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001302737.1_21624001_1 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.4 001302737.1_21624001_1 - 0.0021 17.2 0.1 0.0056 15.8 0.0 1.6 2 0 0 2 2 2 1 Tubulin like Misat_Tub_SegII PF10644.7 001302737.1_21624001_1 - 0.0037 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Sucrose_synth PF00862.17 001302732.1_21625001_3 - 9.2e-283 938.4 0.0 1.2e-282 938.1 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001302732.1_21625001_3 - 6.7e-35 120.1 0.0 1.4e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001302732.1_21625001_3 - 6.6e-11 42.6 0.0 1.6e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001302732.1_21625001_3 - 0.00037 20.7 0.0 0.0015 18.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF1845 PF08900.9 001302732.1_21625001_3 - 0.04 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) OTCace PF00185.22 001302732.1_21625001_3 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain WD40 PF00400.30 001302725.1_21624001_3 - 3.4e-14 52.9 14.2 2.6e-06 27.9 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001302725.1_21624001_3 - 0.00097 19.3 0.1 6.4 7.0 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.4 001302711.1_21622001_1 - 1.9e-13 50.5 3.0 5.3e-09 36.3 0.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001302711.1_21622001_1 - 5.2e-10 38.3 0.1 0.00043 19.9 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.30 001302711.1_21622001_1 - 8e-10 37.4 0.6 0.0002 20.5 0.2 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.4 001302711.1_21622001_1 - 8.9e-07 28.5 0.8 4.8e-05 22.9 0.3 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.4 001302711.1_21622001_1 - 6.1e-05 22.2 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.4 001302711.1_21622001_1 - 0.0025 18.0 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain GPHH PF16905.3 001302711.1_21622001_1 - 0.099 12.3 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated MIP PF00230.18 001302973.1_08322001_1 - 2.5e-84 282.4 10.5 2.8e-84 282.2 10.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.23 001302298.1_45325001_3 - 1.7e-59 201.2 0.0 8.3e-36 123.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.15 001302298.1_45325001_3 - 2.9e-27 95.4 0.0 1.2e-18 67.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.4 001302298.1_45325001_3 - 0.0048 16.1 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pec_lyase_C PF00544.17 001302329.1_45323001_1 - 4.4e-21 75.3 4.6 2.8e-20 72.7 4.6 1.9 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.4 001302329.1_45323001_1 - 6.8e-06 25.9 4.1 1.1e-05 25.2 3.9 1.5 1 1 0 1 1 1 1 Right handed beta helix region PBP PF01161.18 001302325.1_45322001_2 - 3.5e-14 53.1 0.0 3.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_35 PF01301.17 001302331.1_45326001_3 - 6.6e-116 387.2 0.5 8.7e-116 386.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.13 001302331.1_45326001_3 - 6.2e-06 25.7 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.4 001302331.1_45326001_3 - 7.7e-05 23.1 2.5 0.45 11.0 0.1 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain Glyco_hydro_16 PF00722.19 001302275.1_45323001_1 - 2.3e-62 209.5 1.1 3.4e-62 208.9 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 XET_C PF06955.10 001302275.1_45323001_1 - 4.1e-23 80.9 1.3 8.2e-23 80.0 1.3 1.5 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus NIR_SIR PF01077.20 001319809.1_45324001_1 - 4.3e-49 165.9 0.0 2.6e-36 124.4 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.15 001319809.1_45324001_1 - 1.5e-40 136.7 0.0 4.1e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Pollen_allerg_1 PF01357.19 001302322.1_45323001_1 - 3.3e-30 103.8 0.7 5.4e-30 103.1 0.7 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001302322.1_45323001_1 - 3.3e-23 81.6 0.0 7.9e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase DUF1255 PF06865.9 001302322.1_45323001_1 - 0.087 13.1 0.1 0.28 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1255) PEPcase PF00311.15 001319804.1_45327001_1 - 0 1014.4 0.0 0 1014.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.4 001319804.1_45327001_1 - 0.00052 18.5 0.0 0.0009 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Pollen_allerg_1 PF01357.19 001302302.1_45322001_1 - 1.7e-30 104.7 1.1 2.9e-30 104.0 1.1 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001302302.1_45322001_1 - 1.1e-23 83.2 1.4 2.4e-23 82.1 0.0 2.2 3 0 0 3 3 3 1 Lytic transglycolase DUF1255 PF06865.9 001302302.1_45322001_1 - 0.015 15.6 0.1 0.065 13.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1255) adh_short PF00106.23 001302299.1_45323001_1 - 8.8e-44 149.2 0.1 1.1e-43 148.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001302299.1_45323001_1 - 1.1e-32 113.4 0.1 1.5e-32 112.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001302299.1_45323001_1 - 1.1e-07 31.8 0.3 2.1e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.19 001302299.1_45323001_1 - 0.00046 19.6 0.0 0.00075 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.13 001302299.1_45323001_1 - 0.0011 18.1 0.0 0.0018 17.3 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.15 001302299.1_45323001_1 - 0.0041 17.5 0.0 0.0098 16.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.3 001302299.1_45323001_1 - 0.022 14.0 0.0 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Myb_DNA-binding PF00249.29 001302297.1_45324001_1 - 6.8e-15 54.8 0.8 1.5e-14 53.7 0.8 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001302297.1_45324001_1 - 1.2e-05 25.3 0.1 2.7e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001302297.1_45324001_1 - 0.0026 17.5 0.4 0.0052 16.5 0.4 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Glyco_hydro_9 PF00759.17 001302305.1_45324001_1 - 5.5e-136 454.1 0.0 6.3e-136 453.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 ESR1_C PF12743.5 001302305.1_45324001_3 - 0.095 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal PSII_BNR PF14870.4 001302282.1_45324001_1 - 9.3e-125 415.7 1.0 1.1e-124 415.5 1.0 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.3 001302282.1_45324001_1 - 9.3e-11 41.0 0.0 0.00076 18.3 0.0 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.18 001302282.1_45324001_1 - 0.00025 20.5 11.1 3.6 7.8 1.1 5.1 4 0 0 4 4 4 3 BNR/Asp-box repeat Ferritin PF00210.22 001302284.1_45323001_3 - 1.1e-34 119.2 6.2 1.5e-34 118.9 6.2 1.1 1 0 0 1 1 1 1 Ferritin-like domain FCH PF00611.21 001302284.1_45323001_3 - 0.019 15.1 0.4 0.041 14.0 0.4 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Rubrerythrin PF02915.15 001302284.1_45323001_3 - 0.023 14.9 3.5 0.037 14.3 3.4 1.5 1 1 0 1 1 1 0 Rubrerythrin PPP1R35_C PF15503.4 001302284.1_45323001_3 - 0.045 13.4 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Ferritin PF00210.22 001302313.1_45323001_1 - 1.1e-34 119.2 4.7 1.5e-34 118.9 4.7 1.2 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.15 001302313.1_45323001_1 - 0.045 14.0 1.1 0.084 13.1 0.9 1.6 1 1 0 1 1 1 0 Rubrerythrin Pectinesterase PF01095.17 001302330.1_45325001_3 - 6.6e-143 474.7 1.9 8.7e-143 474.3 1.9 1.1 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.13 001302330.1_45325001_3 - 3e-32 111.8 1.8 3e-32 111.8 1.8 2.3 3 0 0 3 3 3 1 Plant invertase/pectin methylesterase inhibitor Pectate_lyase_3 PF12708.5 001302330.1_45325001_3 - 0.0077 16.0 2.5 0.12 12.1 2.5 2.5 1 1 0 1 1 1 1 Pectate lyase superfamily protein IF-2 PF11987.6 001302330.1_45325001_3 - 0.1 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Translation-initiation factor 2 Na_H_Exchanger PF00999.19 001302292.1_45324001_1 - 3.9e-58 196.9 36.7 5.1e-58 196.6 36.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Auxin_repressed PF05564.10 001302326.1_45322001_2 - 6.5e-47 158.9 1.5 9.3e-47 158.4 1.5 1.2 1 0 0 1 1 1 1 Dormancy/auxin associated protein GTP_EFTU PF00009.25 001303081.2_05526001_2 - 8.5e-65 217.8 0.1 1.3e-64 217.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.16 001303081.2_05526001_2 - 6.9e-35 119.3 0.0 1.9e-34 117.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.22 001303081.2_05526001_2 - 6.5e-21 74.0 0.0 2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.23 001303081.2_05526001_2 - 3e-14 53.0 0.0 8.7e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.4 001303081.2_05526001_2 - 3.2e-12 46.2 0.0 6.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.21 001303081.2_05526001_2 - 0.005 16.8 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2892 PF11127.6 131331.1_48423120_1 - 0.038 13.9 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) UreD PF01774.15 131331.1_48423120_3 - 2.2e-52 177.9 0.0 2.9e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein FrhB_FdhB_C PF04432.11 136515.1_48427120_2 - 1.5e-21 76.7 0.0 2.4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.11 136515.1_48427120_3 - 4.1e-25 87.6 0.0 6.9e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term FrhB_FdhB_C PF04432.11 136515.1_48427120_3 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus EDR1 PF14381.4 131258.1_48426120_2 - 3.2e-76 255.5 0.0 4.2e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Pkinase_Tyr PF07714.15 131258.1_48426120_3 - 1e-69 234.6 0.0 1.4e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 131258.1_48426120_3 - 2e-55 187.9 0.0 2.9e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ABC1 PF03109.14 131258.1_48426120_3 - 0.036 14.1 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family APH PF01636.21 131258.1_48426120_3 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Transposase_24 PF03004.12 136341.1_48422120_1 - 0.00048 20.1 0.2 0.0028 17.6 0.2 2.0 1 1 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) Auxin_resp PF06507.11 131334.1_48426120_2 - 1.4e-33 114.8 0.1 2.5e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 Auxin response factor B3 PF02362.19 131334.1_48426120_2 - 6.5e-23 80.4 0.0 5.3e-22 77.5 0.0 2.4 3 0 0 3 3 3 1 B3 DNA binding domain AUX_IAA PF02309.14 131334.1_48426120_2 - 7.5e-09 35.7 0.4 0.0025 17.6 0.0 2.5 1 1 1 2 2 2 2 AUX/IAA family Citrate_synt PF00285.19 136340.1_48422120_1 - 0.02 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain RRM_1 PF00076.20 001347950.1_48423001_3 - 4.9e-15 55.0 0.0 8.1e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.4 001347950.1_48423001_3 - 2.6e-07 31.0 8.2 2.6e-07 31.0 8.2 2.2 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.9 001347950.1_48423001_3 - 0.058 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.4 001347950.1_48423001_3 - 0.079 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.14 001323771.1_46324001_1 - 7.4e-22 77.6 44.3 3.1e-15 55.8 32.6 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.4 001323771.1_46324001_1 - 2e-11 43.0 3.7 2e-11 43.0 3.7 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2070 PF09843.7 001323771.1_46324001_1 - 0.27 9.3 4.4 0.55 8.3 4.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) p450 PF00067.20 001323695.1_46324001_1 - 1.9e-102 343.3 0.0 2.2e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.17 001329161.1_16325001_3 - 6.1e-15 55.2 0.8 1.6e-13 50.6 0.8 2.5 1 1 0 1 1 1 1 FAD binding domain FHA PF00498.24 001329161.1_16325001_3 - 7.8e-10 38.8 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Pyr_redox_2 PF07992.12 001329161.1_16325001_3 - 1.2e-05 24.6 1.3 0.0033 16.6 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001329161.1_16325001_3 - 9.7e-05 22.4 0.6 0.00023 21.2 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001329161.1_16325001_3 - 0.0043 16.6 1.0 0.052 13.0 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.22 001329161.1_16325001_3 - 0.006 15.6 0.9 0.0094 14.9 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.8 001329161.1_16325001_3 - 0.038 12.9 0.0 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.5 001329161.1_16325001_3 - 0.038 13.2 0.3 0.056 12.7 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Topo_Zn_Ribbon PF08272.9 001329161.1_16325001_3 - 0.1 12.2 0.4 0.32 10.6 0.4 1.8 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like AlaDh_PNT_C PF01262.19 001329161.1_16325001_3 - 0.1 11.7 0.3 0.18 11.0 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Yop-YscD_cpl PF16697.3 001329161.1_16325001_3 - 0.12 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Pyr_redox PF00070.25 001329161.1_16325001_3 - 0.28 11.6 1.8 0.44 11.0 0.7 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bax1-I PF01027.18 001324969.1_09322001_1 - 3.1e-35 121.7 17.4 3.7e-35 121.5 17.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PDH PF02153.15 001323460.1_48523001_1 - 2.5e-18 65.9 0.0 3.4e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.15 001323460.1_48523001_1 - 6e-12 45.9 0.0 2.2e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.13 001323460.1_48523001_1 - 7.7e-06 26.0 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.17 001323460.1_48523001_1 - 7.8e-05 22.0 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SMC_N PF02463.17 001323460.1_48523001_1 - 0.00073 18.9 0.0 0.0013 18.1 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NAD_Gly3P_dh_N PF01210.21 001323460.1_48523001_1 - 0.0018 18.2 0.0 0.013 15.3 0.0 2.5 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.20 001323460.1_48523001_1 - 0.0019 18.9 0.0 0.0074 17.0 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.16 001323460.1_48523001_1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.19 001323460.1_48523001_1 - 0.089 12.4 0.0 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.18 001323460.1_48523001_1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cupin_1 PF00190.20 001323742.1_46324001_1 - 7.9e-80 265.6 1.1 7.4e-39 132.6 0.0 3.0 3 0 0 3 3 3 2 Cupin Cupin_2 PF07883.9 001323742.1_46324001_1 - 4.6e-09 35.7 0.2 0.00026 20.5 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.10 001323742.1_46324001_1 - 0.0077 15.7 0.1 1.6 8.3 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF861) ARD PF03079.12 001323742.1_46324001_1 - 0.023 14.7 0.2 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family DUF4115 PF13464.4 001323742.1_46324001_1 - 0.028 14.5 0.1 0.079 13.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) PSI_PsaF PF02507.13 001317301.1_52922001_1 - 1.7e-82 275.3 0.0 2.3e-82 274.8 0.0 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit III TFIIA PF03153.11 001317301.1_52922001_3 - 0.095 12.5 1.0 0.11 12.4 1.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Malic_M PF03949.13 001323739.1_46325001_1 - 3.6e-100 334.3 0.1 4.6e-100 334.0 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.17 001323739.1_46325001_1 - 4.1e-78 261.2 0.0 6e-78 260.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Epimerase PF01370.19 001323774.1_46323001_1 - 1.1e-05 25.0 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lipase_3 PF01764.23 001323708.1_46323001_1 - 1.3e-38 131.9 0.0 2.7e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.6 001323708.1_46323001_1 - 2.2e-05 24.0 0.4 0.041 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.5 001323708.1_46323001_1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.5 001323708.1_46323001_1 - 0.04 14.4 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family GHMP_kinases_C PF08544.11 001323708.1_46323001_1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Hydrolase_4 PF12146.6 001323708.1_46323001_1 - 0.19 10.9 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF642 PF04862.10 001323747.1_46323001_1 - 1.6e-90 300.8 0.0 4e-73 244.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF642) Acyltransferase PF01553.19 001323700.1_46323001_1 - 3.6e-18 65.3 0.0 5.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.3 001323700.1_46323001_1 - 2.8e-16 59.3 0.0 6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Staygreen PF12638.5 001324918.1_09322001_2 - 2e-59 199.5 0.0 2.5e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Staygreen protein Citrate_synt PF00285.19 001326505.1_44324001_3 - 2.6e-129 431.3 0.0 3.1e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MBOAT PF03062.17 001323715.1_46324001_2 - 1.8e-64 218.2 4.8 1.8e-64 218.2 4.8 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PsbK PF02533.13 001323715.1_46324001_2 - 2.6 8.1 8.7 13 5.8 0.9 2.8 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component Lipase_3 PF01764.23 001323724.1_46324001_1 - 6e-40 136.3 0.0 1.4e-39 135.1 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.6 001323724.1_46324001_1 - 0.00012 21.6 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.5 001323724.1_46324001_1 - 0.0062 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.5 001323724.1_46324001_1 - 0.014 15.9 0.0 0.049 14.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001323724.1_46324001_1 - 0.015 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.18 001323724.1_46324001_1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.18 001323724.1_46324001_1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lycopene_cycl PF05834.10 001328461.1_14824001_3 - 1.2e-144 482.0 0.0 1.4e-144 481.7 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.12 001328461.1_14824001_3 - 8.3e-08 31.7 0.6 0.0011 18.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001328461.1_14824001_3 - 4.2e-05 23.2 0.4 0.04 13.4 0.5 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.15 001328461.1_14824001_3 - 4.8e-05 22.6 0.1 0.0078 15.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.5 001328461.1_14824001_3 - 5.7e-05 22.5 0.9 0.00031 20.1 0.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.22 001328461.1_14824001_3 - 0.0004 19.4 0.4 0.00066 18.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.12 001328461.1_14824001_3 - 0.0008 18.1 1.4 0.0014 17.3 0.3 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.4 001328461.1_14824001_3 - 0.00093 19.3 0.2 0.0059 16.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.25 001328461.1_14824001_3 - 0.0012 19.3 0.2 0.083 13.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.12 001328461.1_14824001_3 - 0.0015 17.4 0.2 0.27 9.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.17 001328461.1_14824001_3 - 0.0029 16.8 0.6 0.0043 16.2 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.4 001328461.1_14824001_3 - 0.0034 16.5 2.2 0.021 13.9 2.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001328461.1_14824001_3 - 0.0042 16.1 1.5 0.029 13.3 1.5 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A XdhC_C PF13478.4 001328461.1_14824001_3 - 0.063 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_9 PF13454.4 001328461.1_14824001_3 - 0.076 12.9 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding p450 PF00067.20 001323696.1_46324001_1 - 2.6e-104 349.4 0.0 3.3e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-Dof PF02701.13 001318616.1_48623001_1 - 2.4e-32 110.7 10.1 5.4e-32 109.6 10.1 1.6 1 0 0 1 1 1 1 Dof domain, zinc finger NAD_Gly3P_dh_C PF07479.12 001323699.1_46325001_3 - 1.7e-23 83.3 0.0 2.8e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.21 001323699.1_46325001_3 - 1.2e-12 48.0 0.0 4.2e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lipase_3 PF01764.23 001323736.1_46324001_1 - 2.7e-43 147.1 0.1 5.9e-43 146.0 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.6 001323736.1_46324001_1 - 0.00017 21.1 0.1 0.088 12.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.5 001323736.1_46324001_1 - 0.022 14.4 0.0 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001323736.1_46324001_1 - 0.032 13.4 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.5 001323736.1_46324001_1 - 0.094 13.2 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PPO1_KFDV PF12143.6 001323852.1_53924001_3 - 2.2e-52 176.4 0.5 3.1e-52 176.0 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF_B2219) Tyrosinase PF00264.18 001323852.1_53924001_3 - 3e-31 109.3 3.2 7.4e-31 108.0 3.2 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase PPO1_DWL PF12142.6 001323852.1_53924001_3 - 2.5e-28 97.5 1.2 4.5e-28 96.7 1.2 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain Spermine_synth PF01564.15 001323852.1_53924001_3 - 0.051 12.4 0.1 0.082 11.7 0.1 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase LCAT PF02450.13 001323718.1_46324001_1 - 5.9e-67 226.4 0.0 6.7e-47 160.4 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase DUF4708 PF15813.3 001323718.1_46324001_1 - 0.22 10.5 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) AhpC-TSA PF00578.19 001317288.1_52922001_1 - 1e-39 135.1 0.0 1.4e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001317288.1_52922001_1 - 1.7e-14 53.6 0.0 2.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 001317288.1_52922001_1 - 2.5e-11 43.1 0.1 4.8e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Acyl-ACP_TE PF01643.15 001323751.1_46323001_1 - 1.2e-98 329.2 0.3 1.5e-98 328.9 0.3 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase Gp_dh_C PF02800.18 001323870.1_53923001_1 - 7.9e-72 239.9 0.0 1.1e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001323870.1_53923001_1 - 2.8e-34 117.3 0.1 7.2e-34 116.0 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001323870.1_53923001_1 - 0.01 15.8 0.2 0.026 14.5 0.1 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.17 001323870.1_53923001_1 - 0.078 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.19 001327416.1_24423001_1 - 2.4e-25 89.3 0.0 3.5e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001327416.1_24423001_1 - 9.2e-18 64.1 0.0 1.4e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001327416.1_24423001_1 - 2.5e-14 53.5 0.0 7.1e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001327416.1_24423001_1 - 7.7e-14 51.3 0.0 1e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.3 001327416.1_24423001_1 - 1.2e-12 47.8 0.0 4.2e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.11 001327416.1_24423001_1 - 3e-08 33.4 0.1 5.5e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.13 001327416.1_24423001_1 - 0.0019 17.2 0.1 0.0036 16.4 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.8 001327416.1_24423001_1 - 0.01 15.6 0.1 0.032 14.0 0.1 1.7 1 1 0 1 1 1 0 KR domain adh_short PF00106.23 001327416.1_24423001_1 - 0.054 12.8 0.1 0.21 10.9 0.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase MAS20 PF02064.13 001327416.1_24423001_1 - 4.6 7.2 8.5 8.7 6.3 8.5 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor SR-25 PF10500.7 001327416.1_24423001_2 - 3.7 7.0 16.5 5.3 6.5 16.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OAD_gamma PF04277.11 001327416.1_24423001_2 - 5.6 7.5 8.2 11 6.6 8.2 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Lipase_3 PF01764.23 001323749.1_46323001_1 - 1.4e-37 128.5 0.0 2.3e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.5 001323749.1_46323001_1 - 0.00042 20.9 0.0 0.001 19.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.6 001323749.1_46323001_1 - 0.00043 19.8 0.0 0.051 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.18 001323749.1_46323001_1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001323749.1_46323001_1 - 0.0061 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.5 001323749.1_46323001_1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.13 001323749.1_46323001_1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase p450 PF00067.20 001323694.1_46324001_1 - 7.3e-106 354.5 0.0 9.1e-106 354.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2333 PF10095.7 001323694.1_46324001_1 - 0.018 14.0 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Latarcin PF10279.7 001323694.1_46324001_1 - 0.2 12.0 0.9 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Latarcin precursor S6PP PF05116.11 001323692.1_46324001_3 - 9.4e-103 342.9 0.0 1.2e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase S6PP_C PF08472.8 001323692.1_46324001_3 - 2.7e-54 182.5 0.0 5.1e-54 181.6 0.0 1.5 1 0 0 1 1 1 1 Sucrose-6-phosphate phosphohydrolase C-terminal Hydrolase_3 PF08282.10 001323692.1_46324001_3 - 5.9e-16 58.8 0.0 1.4e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PMM PF03332.11 001323692.1_46324001_3 - 0.00068 19.3 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Amino_oxidase PF01593.22 001329175.1_16325001_3 - 1.6e-82 278.0 0.0 2e-82 277.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001329175.1_16325001_3 - 2.8e-14 53.0 0.1 7.3e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001329175.1_16325001_3 - 5.1e-09 36.1 0.0 0.00041 19.9 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 001329175.1_16325001_3 - 1.9e-07 30.5 0.1 0.0015 17.7 0.2 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001329175.1_16325001_3 - 8.6e-06 26.1 0.1 0.053 14.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001329175.1_16325001_3 - 0.00026 19.7 0.6 0.094 11.3 0.7 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.22 001329175.1_16325001_3 - 0.00055 19.0 0.9 0.00086 18.4 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.9 001329175.1_16325001_3 - 0.00056 18.7 0.0 0.58 8.7 0.0 2.2 2 0 0 2 2 2 2 MCRA family FAD_oxidored PF12831.5 001329175.1_16325001_3 - 0.00065 19.0 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.15 001329175.1_16325001_3 - 0.0018 17.5 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.17 001329175.1_16325001_3 - 0.0034 16.6 0.1 0.0057 15.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.12 001329175.1_16325001_3 - 0.019 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RNase_H2-Ydr279 PF09468.8 001329175.1_16325001_3 - 0.029 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Lycopene_cycl PF05834.10 001329175.1_16325001_3 - 0.057 12.3 0.2 0.23 10.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.12 001329175.1_16325001_3 - 0.074 11.8 0.6 7.6 5.1 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.20 001329175.1_16325001_3 - 1.1 8.2 3.3 1.7 7.5 1.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A AhpC-TSA PF00578.19 001323886.1_53922001_1 - 2.8e-40 136.9 0.0 4.1e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001323886.1_53922001_1 - 3.1e-13 49.5 0.0 4.6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 001323886.1_53922001_1 - 4.5e-11 42.3 0.1 9.2e-11 41.3 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Polysacc_syn_2C PF08485.8 001323886.1_53922001_1 - 0.11 12.1 0.1 9.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal Amino_oxidase PF01593.22 001329165.1_16325001_2 - 3.9e-70 237.2 0.0 4.7e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001329165.1_16325001_2 - 1.1e-14 54.3 0.1 2e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001329165.1_16325001_2 - 5.1e-07 29.5 0.0 1.1e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.9 001329165.1_16325001_2 - 6.9e-05 21.7 0.0 0.0075 15.0 0.0 2.1 2 0 0 2 2 2 2 MCRA family HI0933_like PF03486.12 001329165.1_16325001_2 - 0.00051 18.7 0.1 0.00077 18.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.12 001329165.1_16325001_2 - 0.00078 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.22 001329165.1_16325001_2 - 0.00086 18.4 0.2 0.0014 17.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.5 001329165.1_16325001_2 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.17 001329165.1_16325001_2 - 0.0035 16.5 0.0 0.0068 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.4 001329165.1_16325001_2 - 0.032 14.1 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.20 001329165.1_16325001_2 - 0.039 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.25 001329165.1_16325001_2 - 0.052 14.0 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.19 001329165.1_16325001_2 - 0.054 12.7 0.1 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.16 001329165.1_16325001_2 - 0.059 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.23 001329016.2_29825001_2 - 5.1e-38 130.8 0.0 7.6e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001329016.2_29825001_2 - 4e-35 121.2 0.0 5.7e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRRNT_2 PF08263.10 001329016.2_29825001_2 - 1.4e-09 37.9 4.7 2.8e-09 37.0 4.7 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001329016.2_29825001_2 - 6e-08 32.7 18.6 0.002 18.3 1.0 4.3 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001329016.2_29825001_2 - 1.5e-07 30.9 16.2 0.00014 21.4 6.9 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.31 001329016.2_29825001_2 - 0.0037 17.4 13.7 0.95 10.0 0.1 5.6 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.4 001329016.2_29825001_2 - 1.2 9.3 10.5 17 5.6 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeat PPR_2 PF13041.4 001302519.1_35324001_1 - 2.4e-139 453.4 42.5 3.8e-18 65.3 0.1 14.0 2 2 12 14 14 14 14 PPR repeat family PPR_1 PF12854.5 001302519.1_35324001_1 - 1.7e-119 389.0 39.3 2e-13 49.7 0.2 14.6 15 0 0 15 15 15 14 PPR repeat PPR PF01535.18 001302519.1_35324001_1 - 2.1e-88 284.5 35.1 6.9e-08 32.1 0.0 15.3 15 0 0 15 15 15 13 PPR repeat PPR_3 PF13812.4 001302519.1_35324001_1 - 1.1e-57 191.9 20.3 3.2e-13 49.4 0.1 8.3 6 1 2 9 9 9 8 Pentatricopeptide repeat domain PPR_long PF17177.2 001302519.1_35324001_1 - 5.2e-24 84.6 0.0 5.9e-06 25.7 0.0 5.0 1 1 3 5 5 5 4 Pentacotripeptide-repeat region of PROPR MRP-S27 PF10037.7 001302519.1_35324001_1 - 1.7e-09 37.0 4.9 0.0019 17.0 0.3 4.9 2 1 4 6 6 6 3 Mitochondrial 28S ribosomal protein S27 ECSIT PF06239.9 001302519.1_35324001_1 - 0.00075 18.6 0.3 7.3 5.5 0.0 3.7 2 1 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.9 001302519.1_35324001_1 - 0.0016 18.6 7.9 8.5 6.6 0.2 6.5 3 2 3 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) SPOB_a PF14689.4 001302519.1_35324001_1 - 0.003 17.1 0.1 50 3.6 0.0 5.5 7 0 0 7 7 7 0 Sensor_kinase_SpoOB-type, alpha-helical domain ATP13 PF12921.5 001302519.1_35324001_1 - 0.012 15.3 0.1 4.3 7.1 0.0 4.5 2 2 2 4 4 4 0 Mitochondrial ATPase expression TPR_14 PF13428.4 001302519.1_35324001_1 - 0.017 15.8 0.0 2.5e+02 2.8 0.0 6.6 9 1 1 10 10 9 0 Tetratricopeptide repeat MIP PF00230.18 001302526.1_35322001_1 - 2.2e-36 125.6 18.9 2.7e-36 125.3 18.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein ODV-E18 PF10717.7 001302526.1_35322001_1 - 0.25 11.1 7.3 0.45 10.3 3.2 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Allene_ox_cyc PF06351.9 001302515.1_35323001_2 - 3.4e-91 303.4 0.1 4.6e-91 303.0 0.1 1.2 1 0 0 1 1 1 1 Allene oxide cyclase Dirigent PF03018.12 001302515.1_35323001_2 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Dirigent-like protein Mis12 PF05859.10 001302516.1_35323001_2 - 7.8e-22 77.7 0.2 7.8e-22 77.7 0.2 1.6 2 0 0 2 2 2 1 Mis12 protein ApbA_C PF08546.9 001302516.1_35323001_2 - 0.0057 16.7 0.3 0.052 13.6 0.2 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DUF342 PF03961.11 001302516.1_35323001_2 - 0.061 11.8 0.9 0.094 11.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.12 001302516.1_35323001_2 - 0.67 9.6 7.7 1.7 8.3 7.7 1.7 1 1 0 1 1 1 0 IncA protein Spc24 PF08286.9 001302516.1_35323001_2 - 1.8 8.7 6.5 2.7 8.1 2.0 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 MTHFR PF02219.15 001302523.1_35324001_1 - 5.5e-122 406.4 0.0 8.4e-122 405.8 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DNA_methylase PF00145.15 001302594.1_35126001_2 - 5.6e-37 127.7 0.0 1.1e-33 116.9 0.0 2.6 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase Chromo PF00385.22 001302594.1_35126001_2 - 2e-10 40.3 0.1 3.8e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BAH PF01426.16 001302594.1_35126001_2 - 1.2e-07 31.4 0.4 3.8e-07 29.8 0.3 1.9 2 0 0 2 2 2 1 BAH domain MTHFR PF02219.15 001302580.1_35124001_1 - 3.7e-123 410.3 0.0 5.7e-123 409.7 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase 2OG-FeII_Oxy PF03171.18 001302582.1_35124001_1 - 2.3e-28 98.5 0.0 4.2e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001302582.1_35124001_1 - 8.9e-24 84.4 0.0 1.6e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Terpene_synth_C PF03936.14 001302564.1_35124001_1 - 5e-106 353.8 9.7 8.1e-106 353.1 9.7 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001302564.1_35124001_1 - 1.3e-50 171.7 7.0 2.8e-50 170.5 7.0 1.6 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain DUF3654 PF12376.6 001302564.1_35124001_1 - 0.033 14.2 5.0 0.7 10.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3654) DNA_methylase PF00145.15 001302606.1_35125001_2 - 4.9e-15 55.6 0.0 1.1e-10 41.3 0.0 2.6 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Tox-SGS PF15651.4 001302606.1_35125001_2 - 0.048 13.8 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin 2OG-FeII_Oxy PF03171.18 001302586.1_35124001_2 - 7.5e-29 100.1 0.0 1.4e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001302586.1_35124001_2 - 8e-25 87.8 0.0 8e-25 87.8 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal START PF01852.17 001302569.1_35127001_1 - 1.1e-51 175.1 0.0 1.9e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 START domain MEKHLA PF08670.9 001302569.1_35127001_1 - 4.6e-48 162.6 0.1 7.7e-48 161.9 0.1 1.4 1 0 0 1 1 1 1 MEKHLA domain Homeobox PF00046.27 001302569.1_35127001_1 - 3.7e-16 58.5 0.8 7.9e-16 57.5 0.8 1.6 1 0 0 1 1 1 1 Homeobox domain bZIP_1 PF00170.19 001302569.1_35127001_1 - 0.0023 17.9 7.2 0.0044 16.9 7.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor GHMP_kinases_N PF00288.24 001302575.1_35123001_1 - 2.9e-20 72.1 0.3 2.9e-20 72.1 0.3 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.11 001302575.1_35123001_1 - 3.8e-06 27.0 0.1 3.8e-06 27.0 0.1 2.6 2 1 1 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.7 001302575.1_35123001_1 - 0.0053 16.2 0.2 0.011 15.2 0.2 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature 2OG-FeII_Oxy PF03171.18 001302577.1_35123001_2 - 2.3e-27 95.3 0.0 4e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001302577.1_35123001_2 - 1.1e-16 61.6 0.0 2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Tryp_alpha_amyl PF00234.20 001302974.1_08322001_1 - 1.3e-08 35.0 25.5 8.4e-08 32.4 25.5 2.0 1 1 0 1 1 1 1 Protease inhibitor/seed storage/LTP family DUF3331 PF11811.6 120822.1_07121120_1 - 0.045 13.5 0.1 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) KTI12 PF08433.8 120822.1_07121120_1 - 0.066 12.5 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Meckelin PF09773.7 120703.1_14821120_3 - 0.013 13.5 4.7 0.014 13.4 4.7 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF1201 PF06716.9 127891.1_53021120_3 - 0.01 15.7 0.4 0.012 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) Antimicrobial12 PF08107.9 127893.1_53020120_2 - 0.09 12.4 0.1 0.16 11.7 0.1 1.4 1 1 0 1 1 1 0 Pleurocidin family F-box PF00646.31 001348175.1_48425001_1 - 2.2e-09 36.8 0.6 6.6e-09 35.3 0.6 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001348175.1_48425001_1 - 6.6e-06 25.8 0.3 2.2e-05 24.1 0.3 1.9 1 0 0 1 1 1 1 F-box-like Kelch_6 PF13964.4 001348175.1_48425001_1 - 2e-05 24.6 8.5 0.0024 17.9 0.1 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.13 001348175.1_48425001_1 - 0.025 14.4 5.6 22 5.1 0.0 5.5 6 0 0 6 6 6 0 Kelch motif Kelch_1 PF01344.23 001348175.1_48425001_1 - 0.048 13.1 2.2 4.9 6.7 0.3 3.6 3 0 0 3 3 3 0 Kelch motif LRR_4 PF12799.5 001303580.1_20528001_2 - 3.9e-38 128.5 53.1 1.8e-07 31.2 0.9 9.9 9 1 1 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001303580.1_20528001_2 - 5.4e-37 125.2 63.2 2.6e-08 33.4 2.5 8.9 4 2 6 11 11 11 10 Leucine rich repeat Pkinase PF00069.23 001303580.1_20528001_2 - 5.9e-36 124.1 0.0 9.1e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001303580.1_20528001_2 - 6.4e-36 123.8 0.0 9.2e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_1 PF00560.31 001303580.1_20528001_2 - 7.9e-14 49.8 55.5 0.46 11.0 0.2 16.4 16 0 0 16 16 16 6 Leucine Rich Repeat LRRNT_2 PF08263.10 001303580.1_20528001_2 - 1.8e-08 34.4 1.1 5.3e-08 32.9 1.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.4 001303580.1_20528001_2 - 1.5e-07 30.8 54.0 0.37 10.8 0.4 14.9 15 0 0 15 15 15 5 Leucine Rich repeat LRR_5 PF13306.4 001303580.1_20528001_2 - 0.037 13.9 0.6 3.5 7.5 0.1 2.8 3 0 0 3 3 3 0 Leucine rich repeats (6 copies) LRR_2 PF07723.11 001303580.1_20528001_2 - 3.1 8.5 13.6 21 5.9 0.5 7.1 9 0 0 9 9 9 0 Leucine Rich Repeat SRF-TF PF00319.16 001303583.1_20522001_2 - 3.2e-23 80.8 0.1 5.3e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001303583.1_20522001_2 - 2.6e-21 75.4 8.8 5.5e-21 74.4 8.8 1.5 1 0 0 1 1 1 1 K-box region Sec8_exocyst PF04048.12 001303583.1_20522001_2 - 0.008 16.0 0.5 1.1 9.0 0.1 2.2 2 0 0 2 2 2 2 Sec8 exocyst complex component specific domain Halogen_Hydrol PF10112.7 001303583.1_20522001_2 - 0.14 12.0 3.5 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein HAP1_N PF04849.11 001303583.1_20522001_2 - 1.6 7.8 9.7 4 6.4 0.9 2.1 1 1 0 2 2 2 0 HAP1 N-terminal conserved region RGP PF03214.11 001319914.1_20523001_2 - 1e-179 596.9 0.0 1.2e-179 596.6 0.0 1.0 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide Glyco_tranf_2_2 PF10111.7 001319914.1_20523001_2 - 0.057 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.24 001319914.1_20523001_2 - 0.08 12.6 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 GTP_EFTU PF00009.25 001303577.1_20524001_2 - 1e-53 181.6 0.0 2.4e-53 180.4 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001303577.1_20524001_2 - 6.3e-38 129.4 0.0 1.3e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001303577.1_20524001_2 - 2.2e-14 53.5 1.2 3.1e-14 53.0 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001303577.1_20524001_2 - 0.0014 18.5 0.2 0.0052 16.7 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001303577.1_20524001_2 - 0.0067 16.3 1.0 0.017 15.0 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 SRPRB PF09439.8 001303577.1_20524001_2 - 0.02 14.2 0.1 0.29 10.4 0.1 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FlpD PF02662.14 001303577.1_20524001_2 - 0.064 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit AAA_22 PF13401.4 001303577.1_20524001_2 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Semialdhyde_dhC PF02774.16 001303577.1_20524001_2 - 0.15 12.0 0.2 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain K_trans PF02705.14 001317732.1_20525001_1 - 2.7e-188 626.7 22.9 3.3e-188 626.4 22.9 1.1 1 0 0 1 1 1 1 K+ potassium transporter Thg1 PF04446.10 001317732.1_20525001_1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 tRNAHis guanylyltransferase K-box PF01486.15 001319908.1_20522001_1 - 4.3e-27 94.0 13.1 4.3e-27 94.0 13.1 1.6 2 0 0 2 2 2 1 K-box region SRF-TF PF00319.16 001319908.1_20522001_1 - 2.2e-26 90.9 0.3 3.7e-26 90.2 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Nnf1 PF03980.12 001319908.1_20522001_1 - 3.4 7.9 12.2 6.8 7.0 4.7 2.6 1 1 2 3 3 3 0 Nnf1 SRF-TF PF00319.16 001319915.1_20523001_3 - 1.3e-24 85.3 0.4 2.3e-24 84.5 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001319915.1_20523001_3 - 1.8e-21 75.9 3.6 1.8e-21 75.9 3.6 1.7 2 0 0 2 2 2 1 K-box region ERG2_Sigma1R PF04622.10 001319915.1_20523001_3 - 0.076 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein DUF1192 PF06698.9 001319915.1_20523001_3 - 0.41 10.6 2.3 0.26 11.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Occludin_ELL PF07303.11 001319915.1_20523001_3 - 0.94 10.1 7.6 0.58 10.8 4.7 2.0 2 0 0 2 2 2 0 Occludin homology domain ChaC PF04752.10 001304425.1_20522001_2 - 2.4e-44 151.4 0.0 3.2e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein Actin PF00022.17 001319906.1_20523001_2 - 1.1e-148 495.0 0.0 3.3e-148 493.5 0.0 1.6 1 1 0 1 1 1 1 Actin Bax1-I PF01027.18 001319911.1_20522001_1 - 1.1e-45 155.9 32.0 1.2e-45 155.7 32.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CPSase_L_D2 PF02786.15 001303559.1_20525001_2 - 3.5e-78 261.8 0.0 5.5e-78 261.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.20 001303559.1_20525001_2 - 7.7e-40 135.7 0.0 1.4e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.17 001303559.1_20525001_2 - 2.2e-39 133.8 0.0 2.4e-38 130.4 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.4 001303559.1_20525001_2 - 9.6e-07 27.7 0.0 5.6e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.20 001303559.1_20525001_2 - 4.8e-06 26.1 0.0 1e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.11 001303559.1_20525001_2 - 8.1e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.9 001303559.1_20525001_2 - 0.0067 15.9 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain AP_endonuc_2 PF01261.22 001303559.1_20525001_2 - 0.013 14.9 0.0 6.3 6.0 0.0 3.0 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel ATP-grasp_5 PF13549.4 001303559.1_20525001_2 - 0.031 13.6 0.0 0.074 12.4 0.0 1.5 2 0 0 2 2 2 0 ATP-grasp domain K-box PF01486.15 001303592.1_20523001_3 - 3.4e-30 103.9 14.3 6.3e-30 103.1 14.3 1.4 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001303592.1_20523001_3 - 1.9e-25 87.9 0.3 3.1e-25 87.2 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF342 PF03961.11 001303592.1_20523001_3 - 1.6 7.1 5.5 2.4 6.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MIP PF00230.18 001303605.1_20523001_2 - 1.7e-81 273.1 12.9 2e-81 272.9 12.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein AUX_IAA PF02309.14 001303591.1_20522001_3 - 2.7e-63 213.9 1.2 3.1e-59 200.6 1.2 3.0 1 1 0 1 1 1 1 AUX/IAA family EF1_GNE PF00736.17 001319916.1_20523001_3 - 7.4e-34 115.7 0.6 1.4e-33 114.8 0.6 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_3 PF14497.4 001319916.1_20523001_3 - 0.00055 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001319916.1_20523001_3 - 0.0038 17.3 0.0 0.021 14.9 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001319916.1_20523001_3 - 0.046 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain K-box PF01486.15 001305068.1_20522001_2 - 2.4e-28 98.0 8.4 5.2e-28 96.9 8.4 1.5 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001305068.1_20522001_2 - 1.3e-26 91.7 0.2 2.1e-26 91.0 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CENP-F_leu_zip PF10473.7 001305068.1_20522001_2 - 0.95 9.3 8.9 5 7.0 8.9 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DXP_synthase_N PF13292.4 001303573.1_20525001_1 - 3.2e-113 377.4 0.1 5.1e-113 376.7 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.22 001303573.1_20525001_1 - 1.6e-43 148.3 0.2 3.7e-43 147.1 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 001303573.1_20525001_1 - 1.2e-30 105.8 0.0 2.1e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.19 001303573.1_20525001_1 - 1.3e-06 28.2 0.4 4e-05 23.3 0.3 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.18 001303573.1_20525001_1 - 7.2e-06 25.0 0.1 1.5e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.19 001303573.1_20525001_1 - 0.00024 20.0 0.0 0.039 12.8 0.1 3.0 4 0 0 4 4 4 1 Transketolase, thiamine diphosphate binding domain SeleniumBinding PF11524.6 001303573.1_20525001_1 - 0.074 13.4 0.0 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 Selenium binding protein GPAT_N PF14829.4 001303609.1_20525001_1 - 1.6e-35 120.8 0.0 4.4e-35 119.4 0.0 1.8 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase N-terminal Acyltransferase PF01553.19 001303609.1_20525001_1 - 2.7e-15 56.1 0.0 4.4e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase 14-3-3 PF00244.18 001319912.1_20523001_1 - 3.2e-103 343.9 3.1 3.8e-103 343.6 3.1 1.1 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.15 001319912.1_20523001_1 - 0.024 12.9 2.5 0.039 12.2 2.5 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 UPF0160 PF03690.11 001319912.1_20523001_1 - 0.035 13.6 0.2 0.061 12.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) AP2 PF00847.18 001303564.1_20524001_2 - 1.3e-23 82.9 8.1 3.6e-12 46.2 3.5 2.6 2 0 0 2 2 2 2 AP2 domain DUF2967 PF11179.6 001303564.1_20524001_2 - 0.2 10.9 6.1 0.041 13.2 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Spt20 PF12090.6 001303564.1_20524001_2 - 2 7.8 5.4 4.5 6.7 2.4 2.1 2 0 0 2 2 2 0 Spt20 family DUF3700 PF12481.6 001319917.1_20523001_2 - 6.3e-106 352.8 0.0 7.5e-106 352.5 0.0 1.1 1 0 0 1 1 1 1 Aluminium induced protein GATase_7 PF13537.4 001319917.1_20523001_2 - 5e-05 23.1 0.0 7.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001319917.1_20523001_2 - 0.026 14.6 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain DUF4588 PF15251.4 001304427.1_20523001_3 - 0.0074 16.0 3.6 0.021 14.5 3.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) CBFD_NFYB_HMF PF00808.21 001319907.1_20523001_2 - 2.8e-21 75.4 1.6 5.5e-21 74.5 1.6 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001319907.1_20523001_2 - 1.6e-15 57.5 2.9 1.6e-15 57.5 2.9 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.11 001319907.1_20523001_2 - 1.2 8.9 7.3 1.5 8.6 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tetraspannin PF00335.18 001319909.1_20523001_3 - 5.7e-31 107.8 6.9 8e-31 107.4 6.9 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1510 PF07423.9 001319909.1_20523001_3 - 0.028 13.7 2.0 0.97 8.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF2207 PF09972.7 001319909.1_20523001_3 - 0.11 11.1 11.2 0.19 10.3 8.4 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) BRI3BP PF14965.4 001319909.1_20523001_3 - 3.9 6.8 11.7 2.5 7.4 7.7 2.4 3 0 0 3 3 3 0 Negative regulator of p53/TP53 zf-C3HC4_3 PF13920.4 001303597.1_20523001_1 - 1.5e-08 34.2 15.8 2.9e-08 33.3 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001303597.1_20523001_1 - 0.00057 19.6 16.5 0.0012 18.6 16.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ADIP PF11559.6 001303597.1_20523001_1 - 0.0044 17.0 3.5 0.0046 16.9 2.2 1.5 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding Atg14 PF10186.7 001303597.1_20523001_1 - 0.043 12.8 4.4 0.089 11.7 4.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YjcZ PF13990.4 001303597.1_20523001_1 - 0.14 11.4 1.6 0.19 10.9 1.6 1.1 1 0 0 1 1 1 0 YjcZ-like protein NYD-SP28_assoc PF14775.4 001303597.1_20523001_1 - 0.46 10.5 2.9 1.4 8.9 2.9 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain Sipho_Gp157 PF05565.9 001303597.1_20523001_1 - 0.82 9.5 11.2 2.8 7.8 4.0 2.2 1 1 1 2 2 2 0 Siphovirus Gp157 eIF-4B PF06273.9 001303597.1_20523001_1 - 2.4 7.0 7.2 3.3 6.5 7.2 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF4057 PF13266.4 001348290.1_48423001_1 - 2.2e-141 470.7 7.9 4e-141 469.9 7.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4057) BRD4_CDT PF17105.3 144627.1_53022120_1 - 2.8 7.5 8.8 11 5.6 0.2 2.4 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 WRKY PF03106.13 001250616.1_24122001_1 - 2.4e-25 88.5 7.2 4.2e-25 87.7 7.2 1.4 1 0 0 1 1 1 1 WRKY DNA -binding domain p450 PF00067.20 001349002.1_35224001_1 - 4.6e-94 315.6 0.0 5.7e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.23 001323856.1_53927001_2 - 4.2e-62 209.8 0.0 6.2e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PAS_9 PF13426.5 001323856.1_53927001_2 - 1.2e-42 144.2 0.0 2.1e-20 72.8 0.0 3.3 3 0 0 3 3 3 2 PAS domain Pkinase_Tyr PF07714.15 001323856.1_53927001_2 - 7.3e-28 97.4 0.0 8.6e-26 90.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PAS_3 PF08447.10 001323856.1_53927001_2 - 1.4e-18 66.8 0.0 8.5e-08 32.2 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS PF00989.23 001323856.1_53927001_2 - 4.2e-17 62.0 0.0 1.9e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.8 001323856.1_53927001_2 - 4.8e-08 33.1 0.0 0.0086 16.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold Kinase-like PF14531.4 001323856.1_53927001_2 - 5e-05 22.6 0.0 0.00093 18.5 0.0 2.1 1 1 0 1 1 1 1 Kinase-like PAS_8 PF13188.5 001323856.1_53927001_2 - 0.014 15.3 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 PAS domain DUF1180 PF06679.10 001323856.1_53927001_2 - 2.6 8.3 5.1 0.64 10.3 0.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1180) Glyco_hydro_17 PF00332.16 001318642.1_48623001_1 - 5.5e-69 232.8 0.1 8.5e-69 232.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001318642.1_48623001_1 - 3.1e-18 66.1 7.5 6.6e-18 65.0 7.5 1.6 1 0 0 1 1 1 1 X8 domain GTP_cyclohydro2 PF00925.18 001318642.1_48623001_1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II Mito_carr PF00153.25 001288217.1_48623001_1 - 1.4e-61 204.3 0.3 4e-19 68.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Alpha-amyl_C2 PF07821.10 001329839.1_52823001_1 - 8.1e-21 73.9 0.2 2.5e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.22 001329839.1_52823001_1 - 1.3e-14 54.4 0.0 1.1e-12 48.1 0.0 2.5 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.14 001329839.1_52823001_1 - 0.018 13.1 0.0 0.72 7.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 Raffinose_syn PF05691.10 001329819.1_52827001_3 - 0 1071.0 0.0 0 1070.8 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Clat_adaptor_s PF01217.18 001301957.1_07122001_2 - 3.9e-21 75.3 0.5 4.9e-21 75.0 0.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sugar_tr PF00083.22 001326210.1_35224001_1 - 3.1e-47 161.4 22.3 4.5e-47 160.8 22.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001326210.1_35224001_1 - 3.5e-22 78.7 26.1 1.6e-20 73.2 28.0 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.20 001302563.1_35122001_3 - 2.5e-22 78.3 0.0 3.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001302563.1_35122001_3 - 7.3e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.6 001302563.1_35122001_3 - 0.026 14.4 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.3 001302563.1_35122001_3 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF393 PF04134.10 001317318.1_52923001_1 - 4.2e-22 79.5 0.0 5.9e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 PC4 PF02229.14 001301994.1_07122001_2 - 9.4e-24 82.7 0.5 1.6e-23 81.9 0.5 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DEK_C PF08766.9 001301994.1_07122001_2 - 3.5e-16 58.7 0.9 5.8e-16 58.0 0.9 1.4 1 0 0 1 1 1 1 DEK C terminal domain GDPD PF03009.15 001301994.1_07122001_2 - 0.015 14.9 0.2 0.023 14.3 0.2 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Phage_holin_6_1 PF09682.8 001301994.1_07122001_2 - 0.031 14.6 0.4 0.11 12.8 0.0 2.1 2 1 1 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) MIS13 PF08202.9 001301994.1_07122001_2 - 0.036 13.2 7.3 0.049 12.8 7.3 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Thaumatin PF00314.15 001279109.1_12222001_3 - 1.3e-38 132.8 6.1 3.4e-35 121.7 1.1 2.1 1 1 1 2 2 2 2 Thaumatin family Cyclin_N PF00134.21 001325208.1_35223001_1 - 1.4e-28 99.0 1.6 3.4e-28 97.9 1.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001325208.1_35223001_1 - 2.1e-21 76.1 0.3 4.8e-21 74.9 0.3 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Aldedh PF00171.20 001303094.1_05524001_2 - 1.6e-173 577.4 0.0 1.8e-173 577.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.9 001303094.1_05524001_2 - 0.0004 19.8 0.0 0.67 9.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Actin PF00022.17 001317309.1_52924001_3 - 9.7e-148 492.0 0.0 2.7e-147 490.5 0.0 1.6 1 1 0 1 1 1 1 Actin Peptidase_C1 PF00112.21 001325387.1_35223001_2 - 1.3e-78 263.9 1.6 1.7e-78 263.6 1.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001325387.1_35223001_2 - 2.9e-15 56.3 0.9 5.5e-15 55.4 0.9 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 001325387.1_35223001_2 - 3.4e-06 26.0 2.0 0.0015 17.3 0.5 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Hemopexin PF00045.17 001317153.1_52922001_2 - 1.4e-24 85.6 0.8 1.4e-08 34.4 0.0 4.2 4 0 0 4 4 4 3 Hemopexin Autoind_synth PF00765.15 001317153.1_52922001_2 - 0.01 15.2 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 Autoinducer synthase DUF4467 PF14729.4 001317153.1_52922001_2 - 0.086 13.1 7.2 11 6.3 0.1 3.8 5 0 0 5 5 5 0 Domain of unknown function with cystatin-like fold (DUF4467) F-box PF00646.31 100885.4_03723001_2 - 2e-06 27.4 0.2 4.2e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 100885.4_03723001_2 - 0.00026 20.7 0.6 0.00064 19.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like HLH PF00010.24 001331837.1_03725001_2 - 3.6e-14 52.3 1.6 6.3e-14 51.6 1.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_C65 PF10275.7 102577.4_03723001_3 - 1.7e-89 299.4 0.1 2.7e-89 298.7 0.0 1.4 2 0 0 2 2 2 1 Peptidase C65 Otubain OTU PF02338.17 102577.4_03723001_3 - 0.00032 21.0 0.0 0.0039 17.5 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease Resistin PF06954.9 001332951.1_03722001_3 - 0.15 12.5 13.6 0.55 10.7 0.4 3.3 3 0 0 3 3 3 0 Resistin MSL1_dimer PF16801.3 139839.1_03729120_1 - 0.17 11.6 3.6 0.58 9.8 3.6 1.9 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 zf-C2H2_11 PF16622.3 139839.1_03729120_3 - 0.26 10.9 4.0 0.99 9.1 4.0 2.1 1 0 0 1 1 1 0 zinc-finger C2H2-type Abhydrolase_6 PF12697.5 127926.3_03723001_1 - 3.5e-16 60.3 0.0 4.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 127926.3_03723001_1 - 4.2e-13 49.4 0.0 6.6e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 127926.3_03723001_1 - 6.8e-06 25.4 0.0 3.3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.11 127926.3_03723001_1 - 0.0051 16.6 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.5 127926.3_03723001_1 - 0.02 14.5 0.0 0.053 13.1 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.7 127926.3_03723001_1 - 0.021 14.3 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase VirJ PF06057.9 127926.3_03723001_1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Peptidase_S9 PF00326.19 127926.3_03723001_1 - 0.034 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.11 127926.3_03723001_1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.23 127926.3_03723001_1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_8 PF06259.10 127926.3_03723001_1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Reticulon PF02453.15 127928.3_03722001_1 - 5.5e-36 123.8 5.4 6.8e-36 123.5 5.4 1.1 1 0 0 1 1 1 1 Reticulon Halogen_Hydrol PF10112.7 127928.3_03722001_1 - 0.072 13.0 0.5 0.26 11.2 0.3 1.8 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2937 PF11157.6 127928.3_03722001_1 - 0.16 11.6 0.1 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) GST_C PF00043.23 128638.3_03723001_2 - 3e-16 59.3 0.0 5.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 128638.3_03723001_2 - 1.1e-15 57.5 0.0 1.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 128638.3_03723001_2 - 5e-11 42.7 0.0 9.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 128638.3_03723001_2 - 7e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 128638.3_03723001_2 - 2.7e-05 24.2 0.0 4.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 128638.3_03723001_2 - 9.8e-05 22.1 0.0 0.00037 20.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain zf-C3H1 PF10650.7 129516.5_03729001_2 - 5.1e-10 38.8 1.5 5.1e-10 38.8 1.5 2.3 2 0 0 2 2 2 1 Putative zinc-finger domain UPF0184 PF03670.11 129516.5_03729001_2 - 0.035 14.3 0.1 0.33 11.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Na_H_Exchanger PF00999.19 111512.3_03725001_1 - 1.9e-61 207.8 34.0 2.5e-61 207.4 34.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4328 PF14219.4 111512.3_03725001_1 - 5.2 6.4 11.9 0.4 10.1 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4328) Myb_DNA-binding PF00249.29 111963.3_03723001_1 - 1.3e-18 66.7 0.0 1e-09 38.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 111963.3_03723001_1 - 3.2e-07 30.4 0.2 0.00096 19.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 111963.3_03723001_1 - 0.15 11.9 1.9 6.2 6.6 0.1 2.7 3 0 0 3 3 3 0 Myb DNA-binding like polyprenyl_synt PF00348.15 112315.4_03723001_3 - 1.7e-59 200.8 0.0 2.4e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDI PF02234.17 113393.3_03722001_2 - 2.1e-16 59.7 0.2 4e-16 58.8 0.2 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor CDP-OH_P_transf PF01066.19 001035690.1_03724001_1 - 5.9e-17 62.1 0.0 5.9e-17 62.1 0.0 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RseC_MucC PF04246.10 001035690.1_03724001_1 - 0.02 14.7 0.4 0.061 13.2 0.4 1.8 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC EamA PF00892.18 001338936.1_03724001_1 - 3.3e-10 40.1 27.8 4.4e-05 23.5 17.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.9 001338936.1_03724001_1 - 0.00014 21.1 5.6 0.00092 18.4 0.9 2.4 1 1 0 2 2 2 2 UAA transporter family PP2C PF00481.19 115006.3_03723001_2 - 3.4e-70 236.5 0.0 4.5e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C TMEM234 PF10639.7 141024.1_03724120_3 - 0.014 15.3 0.4 0.029 14.3 0.4 1.4 1 0 0 1 1 1 0 Putative transmembrane family 234 LRR_8 PF13855.4 118133.3_03729001_3 - 1.9e-66 219.6 112.3 2.3e-10 40.0 0.6 13.7 4 3 11 16 16 16 16 Leucine rich repeat LRR_4 PF12799.5 118133.3_03729001_3 - 1.4e-57 190.3 102.5 8.6e-06 25.9 0.2 15.9 13 3 3 17 17 17 15 Leucine Rich repeats (2 copies) Pkinase PF00069.23 118133.3_03729001_3 - 4.8e-47 160.4 0.0 7.2e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 118133.3_03729001_3 - 8.3e-44 149.7 0.0 1.6e-43 148.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_1 PF00560.31 118133.3_03729001_3 - 2.1e-16 57.7 99.7 0.22 12.0 0.2 26.3 28 2 1 29 29 29 7 Leucine Rich Repeat LRRNT_2 PF08263.10 118133.3_03729001_3 - 2.2e-12 46.9 1.0 5.4e-12 45.6 1.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Kinase-like PF14531.4 118133.3_03729001_3 - 0.041 13.0 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.14 118133.3_03729001_3 - 0.069 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family LRR_9 PF14580.4 118133.3_03729001_3 - 0.41 10.0 19.3 2.2 7.6 0.1 5.4 3 1 2 5 5 5 0 Leucine-rich repeat tRNA-synt_1d PF00750.17 001341794.1_03724001_3 - 9.8e-123 409.4 0.1 1.3e-122 409.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.13 001341794.1_03724001_3 - 8.3e-32 109.7 0.1 2.5e-31 108.2 0.0 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.14 001341794.1_03724001_3 - 4.8e-16 59.0 0.0 1.6e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Methyltransf_11 PF08241.10 119104.4_03724001_2 - 2.2e-09 37.7 0.0 5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 119104.4_03724001_2 - 9.9e-06 26.1 0.0 2.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.16 119104.4_03724001_2 - 0.00019 20.7 0.0 0.0003 20.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.4 119104.4_03724001_2 - 0.0024 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 119104.4_03724001_2 - 0.051 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.13 119104.4_03724001_2 - 0.062 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF547 PF04784.12 001342429.1_03726001_2 - 3.5e-29 100.9 0.4 2.3e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF547 Lzipper-MIP1 PF14389.4 001342429.1_03726001_2 - 3.2e-22 78.4 3.5 1.1e-21 76.7 3.5 2.0 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 betaPIX_CC PF16523.3 001342429.1_03726001_2 - 0.38 10.4 10.1 0.024 14.3 2.5 2.7 2 1 1 3 3 3 0 betaPIX coiled coil zf-4CXXC_R1 PF10497.7 001342432.1_03724001_1 - 7.9e-37 125.4 12.6 1.8e-36 124.2 12.6 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF260 PF03195.12 143994.1_03721120_1 - 0.0025 18.0 3.6 0.0044 17.2 3.6 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF260 DUF260 PF03195.12 143994.1_03721120_2 - 0.0026 18.0 0.0 0.0036 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF260 LRR_2 PF07723.11 001345065.1_03722001_1 - 8.9e-08 32.3 1.7 2e-07 31.2 0.1 2.5 2 0 0 2 2 2 1 Leucine Rich Repeat F-box PF00646.31 001345065.1_03722001_1 - 5.8e-07 29.1 0.8 3.7e-06 26.5 0.5 2.3 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.5 001345065.1_03722001_1 - 0.00098 18.8 0.9 0.0036 17.0 0.7 2.0 2 0 0 2 2 2 1 F-box-like DUF2420 PF10336.7 001345065.1_03722001_1 - 0.0026 17.6 0.2 0.031 14.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Hydrolase_6 PF13344.4 001203499.1_03723001_1 - 4.1e-36 123.0 0.0 1e-35 121.8 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.4 001203499.1_03723001_1 - 3.1e-19 68.7 0.0 6.7e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.24 001203499.1_03723001_1 - 7.7e-12 45.8 0.0 1e-11 45.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.4 001203499.1_03723001_1 - 9.3e-09 35.5 0.0 8.5e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.8 001203499.1_03723001_1 - 0.00034 20.1 0.0 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Ion_trans_2 PF07885.14 180865.1_03724001_1 - 1.7e-29 101.4 17.9 2.2e-16 59.5 3.1 2.5 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.29 180865.1_03724001_1 - 5.7e-06 25.6 13.0 0.00027 20.1 0.6 2.6 1 1 1 2 2 2 2 Ion transport protein EF-hand_5 PF13202.4 180865.1_03724001_1 - 0.00049 19.4 0.3 0.86 9.1 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 180865.1_03724001_1 - 0.00068 19.9 0.4 0.12 12.7 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.4 180865.1_03724001_1 - 0.0085 15.8 0.1 0.57 10.1 0.1 3.0 2 1 0 2 2 2 1 EF-hand domain Gate PF07670.12 180865.1_03724001_1 - 0.034 14.3 0.7 0.034 14.3 0.7 2.0 1 1 0 1 1 1 0 Nucleoside recognition EF-hand_1 PF00036.30 180865.1_03724001_1 - 0.039 13.4 0.2 11 5.7 0.0 2.8 2 1 0 2 2 2 0 EF hand Tfb4 PF03850.12 137199.1_53723120_2 - 4.3e-10 39.3 1.7 4.3e-10 39.3 1.7 1.4 2 0 0 2 2 2 1 Transcription factor Tfb4 GPCR_chapero_1 PF11904.6 137199.1_53723120_3 - 6e-21 75.1 0.0 8.1e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 GPCR-chaperone Metallophos PF00149.26 145672.1_53723120_1 - 0.013 15.9 0.1 0.016 15.6 0.1 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos_C PF14008.4 145672.1_53723120_2 - 0.00031 21.4 0.0 0.006 17.3 0.0 2.3 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_C PF14008.4 145672.1_53723120_3 - 0.026 15.2 0.0 0.044 14.5 0.0 1.3 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C FA_desaturase PF00487.22 001306039.1_27123001_1 - 8.1e-31 107.6 24.0 1.1e-30 107.2 24.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase FAD_binding_3 PF01494.17 001319685.1_47924001_3 - 5.3e-10 39.0 0.5 5.8e-05 22.4 0.1 3.0 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.12 001319685.1_47924001_3 - 2.6e-06 26.8 0.7 7.1e-06 25.3 0.7 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001319685.1_47924001_3 - 3.9e-05 22.8 0.1 5.8e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.10 001319685.1_47924001_3 - 0.00017 20.7 0.1 0.41 9.5 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.5 001319685.1_47924001_3 - 0.0045 16.3 1.0 0.0074 15.5 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.12 001319685.1_47924001_3 - 0.0071 15.0 0.3 0.012 14.2 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.4 001319685.1_47924001_3 - 0.0095 16.0 0.2 0.024 14.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.15 001319685.1_47924001_3 - 0.01 15.0 0.1 0.02 14.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.22 001319685.1_47924001_3 - 0.027 13.4 0.8 0.05 12.6 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.22 001319685.1_47924001_3 - 0.057 12.9 2.3 0.67 9.4 0.4 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.25 001319685.1_47924001_3 - 0.099 13.1 0.2 0.22 12.0 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.4 001319685.1_47924001_3 - 0.11 11.5 0.6 0.2 10.7 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.12 001319685.1_47924001_3 - 0.54 8.9 2.8 4.4 5.9 1.4 2.3 2 1 0 3 3 3 0 Tryptophan halogenase Oleosin PF01277.15 001305986.1_47922001_3 - 4e-37 126.3 5.0 5.2e-37 125.9 5.0 1.1 1 0 0 1 1 1 1 Oleosin DUF1700 PF08006.9 001305986.1_47922001_3 - 6.5 6.1 7.0 9.2 5.6 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) UDPGT PF00201.16 001319687.1_47923001_1 - 8.3e-21 74.2 0.0 2.3e-20 72.8 0.0 1.5 1 1 1 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001319687.1_47923001_1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Peptidase_C13 PF01650.16 001304404.1_47924001_3 - 2e-114 381.3 0.0 2.8e-114 380.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.20 001304404.1_47924001_3 - 3.6e-06 27.0 0.0 4.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain SRF-TF PF00319.16 001319686.1_47922001_1 - 5.8e-24 83.2 0.2 1e-23 82.4 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001319686.1_47922001_1 - 1e-18 67.1 5.9 1.9e-18 66.3 5.9 1.4 1 0 0 1 1 1 1 K-box region Herpes_BLRF2 PF05812.10 001319686.1_47922001_1 - 0.29 11.2 3.6 0.13 12.3 1.1 1.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein UPF0184 PF03670.11 001319686.1_47922001_1 - 0.46 10.8 3.8 0.23 11.7 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) peroxidase PF00141.21 001319692.1_47923001_1 - 2.4e-70 236.7 0.1 3.3e-70 236.2 0.1 1.1 1 0 0 1 1 1 1 Peroxidase FAM35_C PF15793.3 001319692.1_47923001_1 - 0.13 11.5 0.1 0.37 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein family FAM35, C-terminal Actin PF00022.17 001304413.1_47923001_3 - 1.6e-148 494.5 0.0 5.3e-148 492.8 0.0 1.7 1 1 0 1 1 1 1 Actin PALP PF00291.23 001304408.1_47923001_1 - 5.1e-68 229.5 0.1 5.9e-68 229.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cupin_1 PF00190.20 001304414.1_47925001_2 - 4.5e-37 126.8 0.1 2.7e-30 104.8 0.1 2.4 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.9 001304414.1_47925001_2 - 1.3e-06 27.9 0.0 0.027 14.1 0.0 3.4 2 1 0 2 2 2 2 Cupin domain Vicilin_N PF04702.10 001304414.1_47925001_2 - 0.0024 17.6 43.4 0.0024 17.6 43.4 2.9 2 1 1 3 3 3 2 Vicilin N terminal region Cupin_6 PF12852.5 001304414.1_47925001_2 - 0.0037 16.9 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.17 001304414.1_47925001_2 - 0.024 14.4 0.0 10 5.9 0.0 2.8 3 0 0 3 3 3 0 AraC-like ligand binding domain GRP PF07172.9 001304414.1_47925001_2 - 1.2 9.8 0.0 1.2 9.8 0.0 2.9 2 0 0 2 2 2 0 Glycine rich protein family Catalase PF00199.17 001304397.1_47924001_1 - 7.3e-173 574.9 0.0 8.5e-173 574.7 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.10 001304397.1_47924001_1 - 6e-17 61.5 0.0 1.5e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive adh_short PF00106.23 001304401.1_47923001_3 - 6.6e-39 133.3 0.0 8.9e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001304401.1_47923001_3 - 6.8e-24 84.6 0.0 8.5e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001304401.1_47923001_3 - 1.4e-05 24.9 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.13 001304401.1_47923001_3 - 0.026 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltr_RsmB-F PF01189.15 001304401.1_47923001_3 - 0.049 13.1 0.0 0.072 12.6 0.0 1.1 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Mucin PF01456.15 001304395.1_47924001_1 - 0.17 11.8 0.2 0.3 10.9 0.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein p450 PF00067.20 001304395.1_47924001_2 - 4.3e-82 276.2 0.0 6e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_1 PF00190.20 001304398.1_47924001_3 - 4.4e-62 208.0 0.2 1.1e-33 115.9 0.1 2.8 3 0 0 3 3 3 2 Cupin Cupin_2 PF07883.9 001304398.1_47924001_3 - 9.3e-05 21.9 0.0 0.44 10.2 0.0 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_6 PF12852.5 001304398.1_47924001_3 - 0.004 16.8 0.0 0.43 10.2 0.0 2.5 2 0 0 2 2 2 2 Cupin MGDG_synth PF06925.9 001304402.1_47923001_1 - 2.8e-59 199.9 0.1 4e-59 199.4 0.1 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.14 001304402.1_47923001_1 - 7.5e-10 38.9 0.0 1.2e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.4 001304402.1_47923001_1 - 0.0041 17.4 0.0 0.0094 16.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001304402.1_47923001_1 - 0.046 13.6 1.1 0.16 11.8 0.9 2.0 2 1 0 2 2 2 0 Glycosyltransferase Family 4 p450 PF00067.20 001304410.1_47924001_1 - 2.8e-103 346.0 0.0 3.4e-103 345.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_1 PF00190.20 001304399.1_47924001_3 - 7.1e-73 243.0 0.1 8.1e-37 126.0 0.0 3.2 3 0 0 3 3 3 3 Cupin Cupin_2 PF07883.9 001304399.1_47924001_3 - 4.5e-06 26.1 0.0 0.74 9.4 0.0 3.4 3 0 0 3 3 3 2 Cupin domain ARD PF03079.12 001304399.1_47924001_3 - 0.0017 18.4 0.3 0.35 10.9 0.2 2.5 2 0 0 2 2 2 2 ARD/ARD' family AraC_binding PF02311.17 001304399.1_47924001_3 - 0.0032 17.2 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 AraC-like ligand binding domain GST_N_3 PF13417.4 001304412.1_47922001_1 - 5.7e-20 71.3 0.0 1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001304412.1_47922001_1 - 2.5e-15 56.4 0.0 4.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001304412.1_47922001_1 - 6.6e-08 32.7 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001304412.1_47922001_1 - 2.7e-06 27.1 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 001304412.1_47922001_1 - 0.0014 18.7 0.1 0.0028 17.7 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.2 001304412.1_47922001_1 - 0.0072 16.9 0.0 0.015 15.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.4 001304412.1_47922001_1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FA_desaturase_2 PF03405.12 001304406.1_47923001_1 - 6.1e-158 524.7 0.0 7e-158 524.5 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.15 001304406.1_47923001_1 - 0.0041 17.4 0.0 0.92 9.8 0.1 2.4 2 0 0 2 2 2 2 Rubrerythrin Exonuc_V_gamma PF04257.12 001304406.1_47923001_1 - 0.11 10.6 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Sod_Fe_C PF02777.16 001319689.1_47922001_2 - 9.5e-35 118.7 1.0 1.1e-34 118.5 0.1 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.20 001319689.1_47922001_2 - 1.1e-32 112.2 0.3 1.8e-32 111.5 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Tocopherol_cycl PF14249.4 001304411.1_47924001_1 - 3.6e-145 483.2 8.9 4.3e-145 482.9 8.9 1.1 1 0 0 1 1 1 1 Tocopherol cyclase p450 PF00067.20 001319691.1_47924001_1 - 6.2e-87 292.1 0.0 7.6e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRP14 PF15459.4 001319691.1_47924001_1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Tubulin PF00091.23 001304396.1_47924001_3 - 4.7e-68 229.1 0.0 6.4e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001304396.1_47924001_3 - 3.7e-51 172.5 0.1 5.6e-51 171.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001304396.1_47924001_3 - 0.0094 15.5 0.0 0.028 14.0 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain NAM PF02365.13 001305828.1_01623001_2 - 5.1e-28 97.6 0.3 8.5e-28 96.9 0.3 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein YABBY PF04690.11 001305831.1_01622001_3 - 7.4e-71 237.8 0.9 9.9e-71 237.4 0.9 1.2 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.8 001305831.1_01622001_3 - 2.9e-05 24.4 0.3 5.4e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.17 001305831.1_01622001_3 - 0.00075 19.7 0.3 0.0014 18.8 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box DUF1014 PF06244.10 001305831.1_01622001_3 - 0.0028 18.1 0.0 0.0034 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) Elf1 PF05129.11 001305831.1_01622001_3 - 0.064 13.2 0.5 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_12 PF11331.6 001305831.1_01622001_3 - 0.099 12.3 4.7 0.24 11.1 3.2 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain zf-LSD1 PF06943.10 001305831.1_01622001_3 - 0.12 12.2 3.8 5.4 6.8 0.2 2.4 2 0 0 2 2 2 0 LSD1 zinc finger K-box PF01486.15 001305833.1_01623001_1 - 2.1e-30 104.6 15.0 2.1e-30 104.6 15.0 1.5 2 0 0 2 2 2 1 K-box region SRF-TF PF00319.16 001305833.1_01623001_1 - 6.3e-27 92.7 0.3 1.3e-26 91.6 0.3 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1192 PF06698.9 001305833.1_01623001_1 - 0.012 15.5 0.3 0.012 15.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Auxin_resp PF06507.11 001305826.1_01627001_3 - 5.6e-35 119.3 0.2 9.7e-35 118.5 0.2 1.4 1 0 0 1 1 1 1 Auxin response factor B3 PF02362.19 001305826.1_01627001_3 - 7.2e-23 80.3 0.0 6.7e-22 77.1 0.0 2.4 3 0 0 3 3 3 1 B3 DNA binding domain AUX_IAA PF02309.14 001305826.1_01627001_3 - 2.5e-06 27.4 10.6 8.6e-05 22.4 0.0 3.2 2 1 0 2 2 2 1 AUX/IAA family PB1 PF00564.22 001305826.1_01627001_3 - 0.0076 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Nicastrin PF05450.13 001305826.1_01627001_3 - 0.94 8.7 7.3 1.8 7.8 7.3 1.3 1 0 0 1 1 1 0 Nicastrin AF-4 PF05110.11 001305826.1_01627001_3 - 6 4.7 26.5 8.1 4.3 26.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein K-box PF01486.15 001305829.1_01622001_1 - 4.9e-29 100.2 11.5 4.9e-29 100.2 11.5 1.6 2 0 0 2 2 2 1 K-box region SRF-TF PF00319.16 001305829.1_01622001_1 - 2e-26 91.0 0.3 3.3e-26 90.4 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) ArAE_2_N PF10337.7 001305829.1_01622001_1 - 0.041 12.8 0.2 0.089 11.7 0.0 1.5 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal ZapB PF06005.10 001305829.1_01622001_1 - 8.2 6.8 12.1 1.2e+02 3.1 4.8 2.7 1 1 1 2 2 2 0 Cell division protein ZapB YABBY PF04690.11 001305830.2_01622001_1 - 1.5e-53 181.6 0.3 2.5e-53 180.8 0.3 1.4 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.8 001305830.2_01622001_1 - 7.4e-05 23.1 0.5 0.00014 22.2 0.5 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.17 001305830.2_01622001_1 - 0.00043 20.5 0.3 0.00082 19.6 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box DUF1014 PF06244.10 001305830.2_01622001_1 - 0.054 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) Mu-like_Com PF10122.7 001305830.2_01622001_1 - 0.1 11.9 2.7 0.19 11.1 2.7 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com NAM PF02365.13 001305836.1_01623001_2 - 1.5e-29 102.5 0.7 9.8e-29 99.9 0.5 2.2 3 0 0 3 3 3 1 No apical meristem (NAM) protein Auxin_resp PF06507.11 001305827.1_01626001_3 - 1.7e-32 111.4 0.2 3.1e-32 110.5 0.2 1.5 1 0 0 1 1 1 1 Auxin response factor B3 PF02362.19 001305827.1_01626001_3 - 2.7e-22 78.4 0.0 2.8e-21 75.2 0.0 2.4 2 0 0 2 2 2 1 B3 DNA binding domain AUX_IAA PF02309.14 001305827.1_01626001_3 - 6.8e-09 35.8 0.1 1.9e-06 27.8 0.1 2.8 1 1 0 1 1 1 1 AUX/IAA family K-box PF01486.15 001305834.1_01622001_1 - 1.2e-27 95.8 13.7 1.2e-27 95.8 13.7 1.7 2 0 0 2 2 2 1 K-box region SRF-TF PF00319.16 001305834.1_01622001_1 - 1.7e-25 88.1 0.3 2.5e-25 87.5 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF972 PF06156.11 001305834.1_01622001_1 - 0.31 11.6 4.6 0.12 12.9 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ZapB PF06005.10 001305834.1_01622001_1 - 1.4 9.3 18.7 1.9 8.8 8.6 2.9 2 1 2 4 4 4 0 Cell division protein ZapB Cupin_1 PF00190.20 001308760.1_27124001_1 - 6e-71 236.8 5.0 1.6e-36 125.0 1.1 3.0 3 0 0 3 3 3 2 Cupin Cupin_2 PF07883.9 001308760.1_27124001_1 - 8.1e-05 22.1 0.0 0.04 13.5 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.10 001308760.1_27124001_1 - 0.012 15.1 0.0 1.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) peroxidase PF00141.21 001308704.1_27123001_2 - 2.7e-48 164.5 0.0 4e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase p450 PF00067.20 001306026.1_27124001_1 - 1.6e-77 261.1 0.0 2.2e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MVP_shoulder PF11978.6 001306026.1_27124001_1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Shoulder domain Legionella_OMP PF05150.10 001306026.1_27124001_1 - 0.18 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Ribosom_S12_S23 PF00164.23 001308789.1_27122001_1 - 4.7e-59 197.7 1.0 7e-59 197.2 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF866 PF05907.11 001308694.1_27122001_1 - 1.2e-49 168.1 0.0 1.3e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-NADH-PPase PF09297.9 001308694.1_27122001_1 - 5.9 6.5 7.3 15 5.2 0.2 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Profilin PF00235.17 001308729.1_27121001_1 - 1.8e-44 150.9 0.0 2e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Profilin Robl_LC7 PF03259.15 001308729.1_27121001_1 - 0.092 12.4 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 Roadblock/LC7 domain MFS_1 PF07690.14 001319920.1_27124001_1 - 7.4e-12 44.7 9.0 7.4e-12 44.7 9.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.4 001319920.1_27124001_1 - 5.4e-10 38.2 1.6 5.4e-10 38.2 1.6 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Gate PF07670.12 001319920.1_27124001_1 - 0.0025 17.9 0.7 0.0025 17.9 0.7 3.2 4 0 0 4 4 4 1 Nucleoside recognition MFS_2 PF13347.4 001318706.1_27125001_2 - 6.4e-11 41.3 17.9 7.4e-10 37.8 17.0 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein AAA PF00004.27 001323428.1_48524001_2 - 1.6e-15 57.6 0.0 3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.9 001323428.1_48524001_2 - 0.0002 21.4 0.0 0.00081 19.4 0.0 2.0 2 0 0 2 2 2 1 Torsin AAA PF00004.27 001293890.1_29824001_2 - 1.2e-13 51.4 0.0 4.9e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.9 001293890.1_29824001_2 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Torsin AP2 PF00847.18 001304317.1_43622001_1 - 2e-12 47.0 0.2 4.5e-12 45.9 0.2 1.7 1 0 0 1 1 1 1 AP2 domain Cu-oxidase_4 PF02578.13 001304317.1_43622001_1 - 0.054 13.0 0.1 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase CARD PF00619.19 001290600.1_39922001_1 - 0.0011 18.8 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Caspase recruitment domain Ras PF00071.20 001290605.1_39923001_2 - 1e-56 190.9 0.0 1.2e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001290605.1_39923001_2 - 1.6e-21 76.6 0.0 2.1e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001290605.1_39923001_2 - 2.3e-08 33.5 0.0 3.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001290605.1_39923001_2 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TMEM173 PF15009.4 001319778.1_08423001_1 - 7.2e-122 406.0 0.0 8.5e-122 405.7 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 173 DSBA PF01323.18 001319877.1_08522001_1 - 4.2e-58 196.2 0.0 4.7e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Helicase_C_3 PF13625.4 001319877.1_08522001_1 - 0.027 14.5 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Helicase conserved C-terminal domain TMEM173 PF15009.4 001319879.1_08525001_2 - 2.1e-121 404.4 0.0 2.6e-121 404.2 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 173 NGF PF00243.16 001320170.1_39922001_1 - 5.1e-46 155.4 0.0 6.1e-46 155.1 0.0 1.1 1 0 0 1 1 1 1 Nerve growth factor family Spaetzle PF16077.3 001320170.1_39922001_1 - 0.093 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Spaetzle DMA PF03474.12 001193777.1_29629001_1 - 0.012 15.0 0.1 0.033 13.6 0.1 1.7 1 0 0 1 1 1 0 DMRTA motif TMEM219 PF14940.4 001193777.1_29629001_2 - 1.8e-82 276.3 0.1 2.6e-82 275.8 0.1 1.2 1 0 0 1 1 1 1 Transmembrane 219 V-set PF07686.15 001302781.1_29623001_1 - 0.0084 16.1 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain TRAM_LAG1_CLN8 PF03798.14 001194451.1_29623001_2 - 6.2e-18 65.1 20.9 7.4e-18 64.9 20.9 1.1 1 0 0 1 1 1 1 TLC domain DUF727 PF05303.10 001194191.1_29625001_2 - 9.9e-32 109.0 0.0 1.5e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Glyco_transf_6 PF03414.11 132141.1_39627120_1 - 4e-40 137.4 0.2 5.6e-40 136.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_transf_6 PF03414.11 132141.1_39627120_3 - 5.4e-49 166.5 5.4 7.9e-49 166.0 2.0 2.0 1 1 1 2 2 2 2 Glycosyltransferase family 6 DnaJ PF00226.29 001205038.1_37623001_1 - 2.5e-19 69.0 0.0 7.6e-19 67.5 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain TNF PF00229.16 001323334.1_21222001_1 - 1.6e-39 134.6 0.0 2.6e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Proteasome PF00227.24 001242744.1_37622001_1 - 1.9e-46 157.8 0.1 2.3e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit YedD PF13987.4 001242744.1_37622001_1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 YedD-like protein Hormone_1 PF00103.18 001323333.1_21222001_1 - 5.7e-44 150.3 0.0 6.4e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family MHC_I PF00129.16 001242715.1_37623001_1 - 4.8e-64 215.1 3.1 7e-64 214.5 3.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001242715.1_37623001_1 - 2.6e-14 53.3 0.0 7.4e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001242715.1_37623001_1 - 8.8e-07 29.3 0.2 2.7e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.4 001242715.1_37623001_1 - 6.7e-05 23.0 0.1 0.00046 20.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001242715.1_37623001_1 - 0.00086 19.3 0.2 0.0056 16.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain MHC_I_3 PF16497.3 001242715.1_37623001_1 - 0.0064 15.9 0.3 0.0092 15.3 0.3 1.1 1 0 0 1 1 1 1 MHC-I family domain C2-set_2 PF08205.10 001242715.1_37623001_1 - 0.0098 15.8 0.5 0.071 13.1 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain FOXP-CC PF16159.3 001323781.1_20925001_1 - 3.3e-35 120.4 4.2 3.3e-35 120.4 4.2 4.7 3 1 2 5 5 1 1 FOXP coiled-coil domain Forkhead PF00250.16 001323781.1_20925001_1 - 2.6e-28 98.0 0.2 1e-27 96.1 0.2 2.1 1 0 0 1 1 1 1 Forkhead domain Plasmodium_Vir PF05795.9 001323781.1_20925001_1 - 0.24 10.6 10.4 0.5 9.6 8.4 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein RR_TM4-6 PF06459.10 001323781.1_20925001_1 - 1.1 8.9 22.0 2.7 7.6 22.0 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2347 PF09804.7 001323781.1_20925001_1 - 1.7 8.0 13.9 3.5 7.0 13.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) hDGE_amylase PF14701.4 001323781.1_20925001_1 - 2.1 7.2 19.3 4.6 6.1 19.3 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain TT_ORF1 PF02956.12 001323781.1_20925001_1 - 2.5 6.5 22.5 3.9 5.9 22.5 1.2 1 0 0 1 1 1 0 TT viral orf 1 Membralin PF09746.7 001323781.1_20925001_1 - 4.5 6.1 14.0 9.7 5.0 14.0 1.6 1 0 0 1 1 1 0 Tumour-associated protein CobT PF06213.10 001323781.1_20925001_1 - 6.9 5.8 29.7 12 5.0 29.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Asp-B-Hydro_N PF05279.9 001323781.1_20925001_1 - 7.9 6.3 16.5 16 5.3 16.5 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AIF_C PF14721.4 001323781.1_20925001_1 - 8.7 6.6 11.1 31 4.8 11.1 2.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Folate_carrier PF01770.16 001323781.1_20925001_1 - 9.3 4.7 12.2 15 4.0 12.2 1.3 1 0 0 1 1 1 0 Reduced folate carrier STAT_bind PF02864.13 001323592.1_46428001_3 - 1.2e-64 218.4 0.1 1.9e-64 217.8 0.1 1.3 1 0 0 1 1 1 1 STAT protein, DNA binding domain STAT_alpha PF01017.18 001323592.1_46428001_3 - 4.9e-48 163.2 7.3 8.7e-48 162.4 7.3 1.4 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT2_C PF12188.6 001323592.1_46428001_3 - 7.4e-32 109.0 5.5 8.1e-32 108.8 4.4 1.7 2 0 0 2 2 2 1 Signal transducer and activator of transcription 2 C terminal STAT_int PF02865.15 001323592.1_46428001_3 - 3.3e-29 101.7 2.3 3.3e-29 101.7 2.3 2.4 3 0 0 3 3 3 1 STAT protein, protein interaction domain SH2 PF00017.22 001323592.1_46428001_3 - 5.4e-10 39.1 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain CorA PF01544.16 001323592.1_46428001_3 - 0.33 10.1 2.4 0.58 9.3 2.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein p450 PF00067.20 001323474.1_00424001_1 - 8.1e-128 426.9 0.0 9.2e-128 426.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RLL PF10036.7 001323474.1_00424001_1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein Asp_protease_2 PF13650.4 001292088.2_21229001_1 - 0.00038 20.9 0.0 0.00066 20.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001292088.2_21229001_1 - 0.0046 16.8 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001292088.2_21229001_1 - 0.018 15.5 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001292088.2_21229001_2 - 2.8e-15 56.3 0.1 2.8e-15 56.3 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001292088.2_21229001_2 - 2.3e-14 53.1 0.0 4.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001292088.2_21229001_2 - 0.0012 18.3 0.2 0.0031 17.1 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001292088.2_21229001_2 - 0.0014 18.4 8.4 0.0024 17.6 8.4 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001292088.2_21229001_2 - 0.0077 16.2 12.9 0.016 15.2 12.9 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.17 001292088.2_21229001_2 - 0.031 12.1 2.5 0.043 11.6 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC106 PF15794.3 001292088.2_21229001_2 - 0.051 13.2 5.3 0.089 12.4 5.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TFIIA PF03153.11 001292088.2_21229001_2 - 0.051 13.4 16.5 0.083 12.7 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCHC PF00098.21 001292088.2_21229001_2 - 0.09 12.8 2.2 0.22 11.5 2.2 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF1664 PF07889.10 001292088.2_21229001_2 - 0.22 11.4 3.8 0.22 11.4 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.10 001292088.2_21229001_2 - 0.51 10.6 12.8 1.1 9.6 10.8 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001292088.2_21229001_2 - 0.96 10.0 10.3 2.9 8.5 10.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001292088.2_21229001_2 - 1.1 9.6 17.2 3.6 8.0 17.2 1.9 1 0 0 1 1 1 0 Cell division protein ZapB DUF4106 PF13388.4 001292088.2_21229001_2 - 1.4 7.9 11.0 2.5 7.1 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Spc7 PF08317.9 001292088.2_21229001_2 - 2.9 6.6 11.8 2.9 6.5 10.7 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein TBPIP PF07106.11 001292088.2_21229001_2 - 3.3 7.3 9.7 6.5 6.4 9.7 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.12 001292088.2_21229001_2 - 4 7.1 10.8 9.9 5.8 10.8 1.6 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.6 001292088.2_21229001_2 - 6.1 6.8 13.3 12 5.9 13.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.10 001292088.2_21229001_2 - 6.6 5.9 10.2 14 4.8 10.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 GIT_CC PF16559.3 001292088.2_21229001_2 - 7.4 6.6 10.3 37 4.3 10.3 2.0 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TNF PF00229.16 001291884.1_21222001_1 - 1e-10 41.5 0.0 1.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DUF1049 PF06305.9 001291884.1_21222001_1 - 0.021 14.5 1.4 0.048 13.3 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Orn_Arg_deC_N PF02784.14 001293802.1_21225001_3 - 9.6e-68 228.1 0.0 1.2e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293802.1_21225001_3 - 6.8e-22 77.5 0.0 1.4e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293802.1_21225001_3 - 0.0027 17.0 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001292055.1_21226001_1 - 6.8e-62 209.0 0.1 8.5e-62 208.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001292055.1_21226001_1 - 8.4e-24 83.7 0.0 1.5e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301815.1_21225001_2 - 6.1e-62 209.1 0.1 7.6e-62 208.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301815.1_21225001_2 - 7.5e-24 83.8 0.0 1.4e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301803.1_44829001_3 - 2.6e-62 210.3 0.2 3.4e-62 210.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301803.1_44829001_3 - 5.1e-24 84.4 0.0 9.5e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Asp_protease_2 PF13650.4 001291363.1_44829001_1 - 0.0035 17.9 0.0 0.0063 17.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291363.1_44829001_1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291363.1_44829001_1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291363.1_44829001_2 - 2.1e-15 56.4 0.0 3.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291363.1_44829001_2 - 5.6e-15 55.3 0.0 5.6e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.4 001291363.1_44829001_2 - 0.0049 16.4 0.2 0.0049 16.4 0.2 1.9 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001291363.1_44829001_2 - 0.0091 15.7 2.8 0.015 15.0 2.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC PF00098.21 001291363.1_44829001_2 - 0.076 13.0 2.2 0.35 10.9 2.2 2.3 1 0 0 1 1 1 0 Zinc knuckle ZapB PF06005.10 001291363.1_44829001_2 - 0.1 12.9 7.4 0.21 11.9 7.4 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Rootletin PF15035.4 001291363.1_44829001_2 - 0.71 9.8 7.9 0.033 14.1 2.1 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.13 001291363.1_44829001_2 - 1.4 8.6 3.8 3.4 7.4 3.8 1.6 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.9 001291363.1_44829001_2 - 1.6 7.4 4.7 1.6 7.4 3.5 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Orn_Arg_deC_N PF02784.14 001291772.1_44829001_3 - 2.6e-62 210.3 0.2 3.4e-62 210.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291772.1_44829001_3 - 9.3e-24 83.5 0.0 1.7e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AAA PF00004.27 001293058.1_44823001_2 - 5.8e-43 146.3 0.0 1.3e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293058.1_44823001_2 - 2.4e-07 30.9 0.0 6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293058.1_44823001_2 - 3.1e-06 27.1 0.0 1.7e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293058.1_44823001_2 - 4.1e-06 27.1 0.2 8e-05 22.9 0.0 2.7 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293058.1_44823001_2 - 2.5e-05 24.4 1.4 0.0057 16.8 0.2 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293058.1_44823001_2 - 0.0001 21.5 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293058.1_44823001_2 - 0.0016 17.3 0.0 0.0034 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293058.1_44823001_2 - 0.0018 17.9 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293058.1_44823001_2 - 0.0018 18.3 0.0 0.004 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293058.1_44823001_2 - 0.0025 18.2 0.2 0.021 15.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.19 001293058.1_44823001_2 - 0.0067 15.7 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.9 001293058.1_44823001_2 - 0.0068 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.14 001293058.1_44823001_2 - 0.0078 15.6 0.1 0.14 11.4 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein ATPase PF06745.11 001293058.1_44823001_2 - 0.0089 15.3 0.0 0.025 13.8 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.4 001293058.1_44823001_2 - 0.019 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293058.1_44823001_2 - 0.024 14.7 3.4 0.055 13.6 3.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293058.1_44823001_2 - 0.025 14.1 0.1 0.11 12.1 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293058.1_44823001_2 - 0.029 13.9 0.0 0.07 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.15 001293058.1_44823001_2 - 0.044 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.11 001293058.1_44823001_2 - 0.046 12.7 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.4 001293058.1_44823001_2 - 0.047 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.15 001293058.1_44823001_2 - 0.051 12.5 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.4 001293058.1_44823001_2 - 0.053 12.9 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001293058.1_44823001_2 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.4 001293058.1_44823001_2 - 0.079 12.5 0.5 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.4 001293058.1_44823001_2 - 0.088 13.1 0.5 0.5 10.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.10 001293058.1_44823001_2 - 0.098 11.8 0.0 0.33 10.1 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.4 001293058.1_44823001_2 - 0.12 12.6 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.10 001293058.1_44823001_2 - 0.23 11.3 3.5 1.3 8.9 0.9 2.7 3 0 0 3 3 3 0 Laminin Domain II DivIC PF04977.13 001293058.1_44823001_2 - 0.44 10.2 3.4 1.1 9.0 3.4 1.6 1 0 0 1 1 1 0 Septum formation initiator MscS_porin PF12795.5 001293058.1_44823001_2 - 4.3 6.7 11.6 6.8 6.0 11.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain OAS1_C PF10421.7 001290162.1_44823001_1 - 4.5e-86 286.9 0.3 6.1e-86 286.5 0.3 1.2 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.21 001290162.1_44823001_1 - 1.7e-08 34.5 0.0 4.5e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain DZF PF07528.12 001290162.1_44823001_1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 DZF domain Orn_Arg_deC_N PF02784.14 001293793.1_44824001_1 - 1.5e-67 227.5 0.0 1.9e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293793.1_44824001_1 - 2.4e-19 69.4 0.0 4.5e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293793.1_44824001_1 - 4.9e-05 22.7 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel B12-binding PF02310.17 001293793.1_44824001_1 - 0.16 11.9 0.0 0.51 10.3 0.0 1.8 1 1 0 1 1 1 0 B12 binding domain Pox_F17 PF04767.10 001293793.1_44824001_2 - 1.9 8.9 7.5 2.8 8.3 1.7 2.7 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein WD40 PF00400.30 001284567.1_29523001_2 - 1.7e-37 126.6 22.7 2.1e-08 34.5 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001284567.1_29523001_2 - 2.1e-21 75.9 1.3 4.9e-08 33.0 0.0 6.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001284567.1_29523001_2 - 4.5e-10 39.6 0.0 0.00017 21.4 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001284567.1_29523001_2 - 1.2e-06 27.7 3.6 0.17 10.7 0.0 4.1 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.6 001284567.1_29523001_2 - 2.9e-05 22.7 2.4 0.11 11.0 0.0 2.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.14 001284567.1_29523001_2 - 3.8e-05 22.2 2.0 0.049 12.0 0.1 3.4 1 1 3 4 4 4 4 Cytochrome D1 heme domain HPS3_N PF14761.4 001284567.1_29523001_2 - 0.00032 20.3 0.0 0.072 12.6 0.0 3.0 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 GSDH PF07995.9 001284567.1_29523001_2 - 0.0056 15.9 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 1 Glucose / Sorbosone dehydrogenase PD40 PF07676.10 001284567.1_29523001_2 - 0.0097 15.7 0.2 1.9 8.4 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40_like PF17005.3 001284567.1_29523001_2 - 0.017 14.3 0.1 0.25 10.5 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.9 001284567.1_29523001_2 - 0.043 12.5 0.1 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like Frtz PF11768.6 001284567.1_29523001_2 - 0.053 11.7 0.0 0.084 11.0 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Methyltransf_3 PF01596.15 001283256.1_29522001_1 - 6.6e-56 188.7 0.0 8.6e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001283256.1_29522001_1 - 2.3e-11 44.5 0.0 3.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001283256.1_29522001_1 - 0.0012 19.3 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001283256.1_29522001_1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.17 001283256.1_29522001_1 - 0.017 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.5 001283256.1_29522001_1 - 0.046 13.5 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.4 001283299.1_29524001_2 - 2e-15 56.8 10.0 5.3e-09 36.3 1.3 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.30 001283299.1_29524001_2 - 2.1e-15 54.9 2.9 1.5e-06 27.2 0.1 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.4 001283299.1_29524001_2 - 4.7e-14 50.9 0.5 1e-05 24.9 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain Acyltransferase PF01553.19 001283299.1_29524001_2 - 1.1e-10 41.1 0.0 1.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase EF-hand_5 PF13202.4 001283299.1_29524001_2 - 1.2e-10 40.3 5.8 9.8e-05 21.6 0.2 3.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.4 001283299.1_29524001_2 - 2e-08 33.7 3.9 0.00041 19.9 0.2 3.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.5 001283299.1_29524001_2 - 0.00075 19.3 0.3 0.29 11.0 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand IF2_N PF04760.13 001283299.1_29524001_2 - 0.014 15.0 0.0 0.065 12.9 0.0 2.1 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Caleosin PF05042.11 001283299.1_29524001_2 - 0.15 11.8 0.4 3.8 7.3 0.0 2.4 1 1 1 2 2 2 0 Caleosin related protein APG12 PF04110.11 001285312.1_29524001_2 - 4.8e-40 135.7 0.0 8.5e-40 134.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.14 001285312.1_29524001_2 - 3e-05 24.0 0.0 4.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like RITA PF17066.3 001284769.1_29525001_2 - 2.6e-129 430.4 17.7 3.4e-129 430.0 17.7 1.1 1 0 0 1 1 1 1 RBPJ-interacting and tubulin associated protein AAA_18 PF13238.4 001286227.1_29522001_2 - 8.6e-31 107.0 0.3 1.4e-30 106.3 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.4 001286227.1_29522001_2 - 2.7e-09 37.4 0.0 6.1e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.27 001286227.1_29522001_2 - 8.5e-05 22.9 0.0 0.00019 21.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.20 001286227.1_29522001_2 - 0.00021 21.3 0.8 0.015 15.3 0.0 2.4 2 1 1 3 3 3 1 Shikimate kinase AAA_28 PF13521.4 001286227.1_29522001_2 - 0.0003 20.9 0.0 0.00047 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001286227.1_29522001_2 - 0.0011 19.0 0.1 0.027 14.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain ADK PF00406.20 001286227.1_29522001_2 - 0.0016 18.4 0.0 0.0059 16.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_16 PF13191.4 001286227.1_29522001_2 - 0.002 18.4 0.0 0.0058 16.9 0.0 1.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.4 001286227.1_29522001_2 - 0.0034 17.5 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain dNK PF01712.17 001286227.1_29522001_2 - 0.0058 16.4 2.0 0.77 9.4 0.3 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase NTPase_1 PF03266.13 001286227.1_29522001_2 - 0.0066 16.2 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.12 001286227.1_29522001_2 - 0.0067 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.20 001286227.1_29522001_2 - 0.0099 16.1 0.0 0.028 14.7 0.0 1.7 2 0 0 2 2 2 1 RNA helicase Cytidylate_kin PF02224.16 001286227.1_29522001_2 - 0.024 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase KTI12 PF08433.8 001286227.1_29522001_2 - 0.04 13.2 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RuvB_N PF05496.10 001286227.1_29522001_2 - 0.054 12.6 0.1 0.08 12.1 0.1 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.4 001286227.1_29522001_2 - 0.056 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.4 001286227.1_29522001_2 - 0.07 12.7 1.2 0.12 12.0 0.3 1.8 2 1 0 2 2 2 0 AAA domain TsaE PF02367.15 001286227.1_29522001_2 - 0.075 12.9 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.11 001286227.1_29522001_2 - 0.11 11.7 1.5 0.25 10.5 0.2 1.9 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.9 001286227.1_29522001_2 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EOS1 PF12326.6 001283564.1_29525001_1 - 0.11 12.3 2.6 0.16 11.7 2.6 1.4 1 0 0 1 1 1 0 N-glycosylation protein Sushi PF00084.18 001283564.1_29525001_3 - 1.3e-66 220.9 46.2 3.5e-11 43.4 0.1 7.4 6 1 1 7 7 7 7 Sushi repeat (SCR repeat) DUF3405 PF11885.6 001283564.1_29525001_3 - 0.68 8.3 7.3 0.85 8.0 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Presenilin PF01080.15 001283564.1_29525001_3 - 0.78 8.3 6.3 1.1 7.8 6.3 1.2 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.6 001283564.1_29525001_3 - 1.3 8.8 4.9 1.8 8.3 4.9 1.3 1 0 0 1 1 1 0 N-glycosylation protein Pentapeptide PF00805.20 001260902.1_29625001_1 - 1.7e-34 116.9 23.8 2.7e-12 46.0 1.9 4.5 2 2 1 4 4 4 4 Pentapeptide repeats (8 copies) BTB_2 PF02214.20 001260902.1_29625001_1 - 7e-20 71.1 0.0 1.2e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_4 PF13599.4 001260902.1_29625001_1 - 6.1e-19 67.8 0.7 1.5e-09 37.7 0.0 3.1 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) KHA PF11834.6 001260902.1_29625001_1 - 7.8e-18 64.2 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Pentapeptide_3 PF13576.4 001260902.1_29625001_1 - 1.3e-11 44.3 0.0 2.1e-05 24.5 0.0 4.0 2 1 0 3 3 3 3 Pentapeptide repeats (9 copies) BTB PF00651.29 001260902.1_29625001_1 - 0.00018 21.5 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.3 001260902.1_29625001_1 - 0.0003 20.7 0.0 0.00056 19.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CBFD_NFYB_HMF PF00808.21 001266669.1_29623001_2 - 2.3e-11 43.7 0.0 4.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone USP8_dimer PF08969.9 001260604.1_29625001_3 - 4.8e-21 74.9 0.2 4.8e-21 74.9 0.2 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain JAB PF01398.19 001260604.1_29625001_3 - 1.3e-20 73.4 0.0 1.3e-20 73.4 0.0 2.4 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.4 001260604.1_29625001_3 - 1e-06 28.4 0.0 2.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3526 PF12040.6 001260604.1_29625001_3 - 0.13 12.6 5.4 0.23 11.9 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) FAM176 PF14851.4 001260604.1_29625001_3 - 7.8 6.0 10.0 16 5.1 10.0 1.4 1 0 0 1 1 1 0 FAM176 family BST2 PF16716.3 001279218.1_39622001_1 - 4.4e-36 123.2 9.9 5.8e-36 122.8 9.9 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 MAD PF05557.11 001279218.1_39622001_1 - 1.5e-05 23.4 6.0 1.8e-05 23.2 6.0 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein CALCOCO1 PF07888.9 001279218.1_39622001_1 - 0.00034 19.2 4.0 0.00039 19.0 4.0 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.6 001279218.1_39622001_1 - 0.0025 17.0 3.8 0.0025 17.0 3.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) ATG16 PF08614.9 001279218.1_39622001_1 - 0.0039 17.3 10.3 0.0067 16.5 10.1 1.4 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.3 001279218.1_39622001_1 - 0.0041 17.9 5.9 0.0058 17.4 5.9 1.2 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.6 001279218.1_39622001_1 - 0.0045 17.1 5.8 0.008 16.2 5.8 1.3 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding CCDC-167 PF15188.4 001279218.1_39622001_1 - 0.0046 17.1 4.4 0.0054 16.9 3.4 1.6 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF4618 PF15397.4 001279218.1_39622001_1 - 0.0049 16.2 3.7 0.006 15.9 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Bap31 PF05529.10 001279218.1_39622001_1 - 0.0054 16.2 5.3 0.01 15.3 5.3 1.4 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Spc7 PF08317.9 001279218.1_39622001_1 - 0.006 15.4 5.1 0.0079 15.0 5.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.10 001279218.1_39622001_1 - 0.0074 16.2 6.7 0.013 15.4 6.6 1.5 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.7 001279218.1_39622001_1 - 0.0074 16.4 4.0 0.01 15.9 4.0 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.7 001279218.1_39622001_1 - 0.0099 15.8 4.7 0.0099 15.8 4.7 1.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.11 001279218.1_39622001_1 - 0.016 15.3 4.6 0.023 14.9 4.6 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Golgin_A5 PF09787.7 001279218.1_39622001_1 - 0.018 14.4 5.5 0.023 14.1 5.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 FliJ PF02050.14 001279218.1_39622001_1 - 0.02 15.0 5.5 0.033 14.3 5.5 1.3 1 1 0 1 1 1 0 Flagellar FliJ protein IncA PF04156.12 001279218.1_39622001_1 - 0.022 14.4 15.8 0.0083 15.8 13.0 1.8 1 1 1 2 2 1 0 IncA protein FlaC_arch PF05377.9 001279218.1_39622001_1 - 0.024 14.9 3.1 0.6 10.4 2.1 2.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Filament PF00038.19 001279218.1_39622001_1 - 0.027 13.9 7.6 0.071 12.6 7.6 1.5 1 1 0 1 1 1 0 Intermediate filament protein EMP24_GP25L PF01105.22 001279218.1_39622001_1 - 0.029 14.2 1.1 0.049 13.4 1.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Cob_adeno_trans PF01923.16 001279218.1_39622001_1 - 0.032 14.2 1.1 0.043 13.8 1.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase HAUS-augmin3 PF14932.4 001279218.1_39622001_1 - 0.036 13.5 5.8 0.046 13.1 5.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Tropomyosin_1 PF12718.5 001279218.1_39622001_1 - 0.036 14.0 4.9 0.036 14.0 4.9 1.8 1 1 0 2 2 2 0 Tropomyosin like CASP_C PF08172.10 001279218.1_39622001_1 - 0.04 13.1 3.8 0.03 13.5 2.1 1.5 1 1 0 1 1 1 0 CASP C terminal Reo_sigmaC PF04582.10 001279218.1_39622001_1 - 0.041 13.1 0.7 0.051 12.8 0.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin PF00261.18 001279218.1_39622001_1 - 0.041 13.1 7.2 0.25 10.5 3.2 1.8 1 1 0 1 1 1 0 Tropomyosin DUF342 PF03961.11 001279218.1_39622001_1 - 0.048 12.1 0.7 0.056 11.9 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.10 001279218.1_39622001_1 - 0.05 12.9 5.5 0.063 12.5 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tektin PF03148.12 001279218.1_39622001_1 - 0.058 12.0 9.3 0.14 10.8 3.5 2.0 1 1 1 2 2 2 0 Tektin family Med9 PF07544.11 001279218.1_39622001_1 - 0.068 13.1 0.7 0.16 11.9 0.7 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.17 001279218.1_39622001_1 - 0.072 10.9 1.9 0.087 10.6 1.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.20 001279218.1_39622001_1 - 0.074 13.2 4.4 0.11 12.7 4.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.4 001279218.1_39622001_1 - 0.078 12.5 8.5 0.066 12.7 5.2 1.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc24 PF08286.9 001279218.1_39622001_1 - 0.079 13.1 8.3 0.05 13.7 3.9 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GrpE PF01025.17 001279218.1_39622001_1 - 0.085 12.4 6.2 0.046 13.2 3.8 1.7 1 1 1 2 2 2 0 GrpE CENP-H PF05837.10 001279218.1_39622001_1 - 0.089 13.1 8.5 0.23 11.8 8.1 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FUSC PF04632.10 001279218.1_39622001_1 - 0.11 10.9 2.0 0.15 10.5 2.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4472 PF14739.4 001279218.1_39622001_1 - 0.11 13.1 5.8 1.2 9.8 1.9 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF972 PF06156.11 001279218.1_39622001_1 - 0.12 12.9 3.8 0.1 13.1 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.10 001279218.1_39622001_1 - 0.13 12.1 3.9 3.5 7.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.4 001279218.1_39622001_1 - 0.13 11.4 8.0 0.083 12.1 4.3 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.13 001279218.1_39622001_1 - 0.14 11.8 4.7 0.19 11.5 4.7 1.1 1 0 0 1 1 1 0 Mnd1 family DUF4200 PF13863.4 001279218.1_39622001_1 - 0.19 12.0 7.0 0.32 11.3 7.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ZapB PF06005.10 001279218.1_39622001_1 - 0.2 12.0 8.9 0.11 12.8 3.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Cluap1 PF10234.7 001279218.1_39622001_1 - 0.21 10.8 7.0 0.75 9.0 7.0 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 ERM PF00769.17 001279218.1_39622001_1 - 0.23 11.1 8.0 0.27 10.9 8.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2205 PF10224.7 001279218.1_39622001_1 - 0.24 11.3 6.9 0.35 10.7 3.6 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) EFTUD2 PF16004.3 001279218.1_39622001_1 - 0.24 11.9 2.4 0.34 11.4 2.4 1.3 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus KLRAQ PF10205.7 001279218.1_39622001_1 - 0.25 11.5 6.3 0.31 11.2 2.6 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Nup54 PF13874.4 001279218.1_39622001_1 - 0.31 11.0 7.3 0.25 11.3 2.5 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 KELK PF15796.3 001279218.1_39622001_1 - 0.33 11.3 8.7 0.23 11.8 4.4 2.0 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_DNA_bd PF12329.6 001279218.1_39622001_1 - 0.33 10.9 6.4 0.089 12.7 3.3 1.6 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.10 001279218.1_39622001_1 - 0.34 11.4 7.4 0.29 11.7 1.3 2.4 1 1 2 3 3 3 0 SlyX TMPIT PF07851.11 001279218.1_39622001_1 - 0.37 9.9 2.4 0.47 9.5 2.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.10 001279218.1_39622001_1 - 0.44 10.9 2.9 2.4 8.6 0.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.18 001279218.1_39622001_1 - 0.46 10.4 7.6 1.5 8.7 7.6 1.7 1 1 0 1 1 1 0 Prefoldin subunit CLZ PF16526.3 001279218.1_39622001_1 - 0.63 10.3 5.3 0.43 10.8 3.3 1.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin PF02996.15 001279218.1_39622001_1 - 0.64 9.8 6.6 0.76 9.6 2.5 2.1 1 1 1 2 2 2 0 Prefoldin subunit APC_N_CC PF16689.3 001279218.1_39622001_1 - 0.73 9.8 4.6 0.69 9.9 3.0 1.7 2 0 0 2 2 1 0 Coiled-coil N-terminus of APC, dimerisation domain ABC_tran_CTD PF16326.3 001279218.1_39622001_1 - 0.79 9.9 7.6 8.8 6.5 6.8 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.4 001279218.1_39622001_1 - 1 8.5 7.6 0.26 10.5 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.6 001279218.1_39622001_1 - 1.5 8.8 8.7 8 6.4 8.6 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.13 001279218.1_39622001_1 - 2.2 8.0 10.0 3.2 7.4 4.6 2.9 1 1 2 3 3 3 0 Septum formation initiator OmpH PF03938.12 001279218.1_39622001_1 - 2.2 8.1 10.1 10 6.0 10.2 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4140 PF13600.4 001279218.1_39622001_1 - 2.9 8.3 7.8 18 5.7 7.8 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF948 PF06103.9 001279218.1_39622001_1 - 4.2 7.5 6.7 13 6.0 1.1 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) 7tm_1 PF00001.19 174381.1_06525001_1 - 1.2e-29 103.3 22.1 1.8e-29 102.6 22.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.4 174381.1_06525001_1 - 1.4e-18 66.3 5.3 1.1e-05 24.9 0.3 4.6 3 2 1 4 4 4 4 Leucine rich repeat LRR_5 PF13306.4 174381.1_06525001_1 - 8.1e-13 48.3 13.2 1.9e-07 31.0 1.5 3.1 1 1 1 3 3 3 2 Leucine rich repeats (6 copies) Comm PF15957.3 174381.1_06525001_1 - 0.12 12.6 0.9 0.29 11.4 0.9 1.6 1 0 0 1 1 1 0 Commissureless LRR_4 PF12799.5 174381.1_06525001_1 - 0.14 12.4 3.9 8.4 6.8 0.2 4.0 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_transf_6 PF03414.11 132148.1_29524120_2 - 1.2e-100 336.3 1.5 1.6e-100 335.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 APS_kinase PF01583.18 001290602.1_39925001_3 - 2.3e-75 251.7 0.0 3.7e-75 251.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.15 001290602.1_39925001_3 - 1.4e-70 237.0 0.1 1.9e-70 236.5 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.4 001290602.1_39925001_3 - 2e-48 163.9 0.0 3.9e-48 163.0 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.4 001290602.1_39925001_3 - 1.7e-07 31.4 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001290602.1_39925001_3 - 0.00052 20.4 0.0 0.0022 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.16 001290602.1_39925001_3 - 0.056 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.15 001290602.1_39925001_3 - 0.057 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase PEPCK_ATP PF01293.18 001290602.1_39925001_3 - 0.081 11.4 0.1 0.74 8.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase KTI12 PF08433.8 001290602.1_39925001_3 - 0.082 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF258 PF03193.14 001290602.1_39925001_3 - 0.1 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.10 001290602.1_39925001_3 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ArsA_ATPase PF02374.13 001290603.1_39923001_3 - 1.9e-125 418.1 0.1 2.1e-125 417.9 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.4 001290603.1_39923001_3 - 3.4e-10 40.0 0.0 1.9e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.21 001290603.1_39923001_3 - 3.5e-10 39.9 0.2 2e-09 37.5 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.7 001290603.1_39923001_3 - 5.1e-06 26.0 0.1 0.0002 20.8 0.1 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.10 001290603.1_39923001_3 - 0.00017 21.0 0.0 0.00032 20.1 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.16 001290603.1_39923001_3 - 0.0005 19.5 0.1 0.0011 18.3 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.20 001290603.1_39923001_3 - 0.0018 17.8 0.0 0.0068 15.9 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.4 001290603.1_39923001_3 - 0.0021 17.6 0.0 0.0044 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.10 001290603.1_39923001_3 - 0.024 13.8 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.14 001290603.1_39923001_3 - 0.027 13.8 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.20 001290603.1_39923001_3 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.4 001290603.1_39923001_3 - 0.22 11.9 0.2 0.71 10.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain AICARFT_IMPCHas PF01808.16 001290592.1_39924001_2 - 2.1e-95 319.5 0.0 2.7e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.20 001290592.1_39924001_2 - 2.4e-25 88.4 0.0 4.2e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Ribosomal_L23eN PF03939.11 001301052.1_39922001_1 - 4.5e-28 97.1 17.1 4.5e-28 97.1 17.1 2.3 4 0 0 4 4 4 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.18 001301052.1_39922001_1 - 4e-16 59.0 3.2 4e-16 59.0 3.2 3.2 3 1 0 3 3 3 1 Ribosomal protein L23 Ribosomal_L6 PF00347.21 001301052.1_39922001_1 - 0.061 13.9 1.4 0.083 13.4 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L6 Orn_Arg_deC_N PF02784.14 001301809.1_39928001_1 - 1.6e-63 214.3 0.1 2e-63 214.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301809.1_39928001_1 - 1.5e-24 86.1 0.0 2.7e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Proteasome PF00227.24 001290585.1_39922001_3 - 4.2e-60 202.4 0.0 6.4e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001290585.1_39922001_3 - 6.1e-10 38.5 0.1 1.1e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PBP_dimer PF03717.13 001290585.1_39922001_3 - 0.11 12.7 0.0 9.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain Lyase_1 PF00206.18 001290598.1_39924001_2 - 8.9e-26 90.9 0.0 1.3e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.7 001290598.1_39924001_2 - 4.9e-18 65.3 0.0 1.3e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.4 001290598.1_39924001_2 - 0.0082 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4089) HTH_Tnp_Tc5 PF03221.14 001290598.1_39924001_2 - 0.034 14.0 0.7 0.11 12.4 0.1 2.1 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain DUF1331 PF07048.9 001290598.1_39924001_2 - 0.07 12.7 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) HMG14_17 PF01101.16 001290586.1_39921001_3 - 8.1e-33 113.1 25.6 8.1e-33 113.1 25.6 2.1 2 0 0 2 2 2 1 HMG14 and HMG17 SP_C-Propep PF08999.8 001290610.1_39922001_1 - 4.3e-52 173.7 2.0 6.3e-52 173.2 2.0 1.3 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide BRICHOS PF04089.12 001290610.1_39922001_1 - 2.1e-19 69.3 0.0 3.1e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 BRICHOS domain PTPS_related PF10131.7 001290610.1_39922001_1 - 0.03 12.5 0.0 0.04 12.1 0.0 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF945 PF06097.9 001290610.1_39922001_1 - 0.35 9.8 0.9 0.51 9.2 0.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) SPARC_Ca_bdg PF10591.7 001290612.1_39925001_3 - 1.2e-39 134.9 0.2 2.9e-39 133.8 0.2 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.19 001290612.1_39925001_3 - 3.8e-13 49.1 7.7 4.1e-13 49.0 4.4 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 001290612.1_39925001_3 - 6.2e-11 42.2 2.2 1.6e-10 40.8 2.2 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain FOLN PF09289.8 001290612.1_39925001_3 - 7.9e-10 38.6 8.3 2.3e-09 37.1 8.3 1.9 1 0 0 1 1 1 1 Follistatin/Osteonectin-like EGF domain Fer2_3 PF13085.4 001290613.1_39922001_3 - 1.8e-33 114.6 0.0 3.4e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.4 001290613.1_39922001_3 - 1.3e-09 38.3 4.8 1.3e-09 38.3 4.8 2.6 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.4 001290613.1_39922001_3 - 5.9e-08 32.9 21.6 4.7e-07 30.0 7.4 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.4 001290613.1_39922001_3 - 8.9e-07 28.8 2.5 8.9e-07 28.8 2.5 2.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.25 001290613.1_39922001_3 - 0.0026 17.5 3.2 0.0036 17.1 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.5 001290613.1_39922001_3 - 0.0027 18.1 14.3 0.027 14.9 6.6 3.1 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.4 001290613.1_39922001_3 - 0.0061 16.6 5.0 0.0061 16.6 5.0 3.0 2 2 0 2 2 2 1 4Fe-4S dicluster domain AAA PF00004.27 001293055.1_33723001_1 - 6e-43 146.3 0.0 1.3e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293055.1_33723001_1 - 2.5e-07 30.8 0.0 6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293055.1_33723001_1 - 3.2e-06 27.0 0.0 1.7e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293055.1_33723001_1 - 4.7e-06 27.0 0.2 8.1e-05 22.9 0.0 2.6 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293055.1_33723001_1 - 3.3e-05 24.0 1.7 0.0057 16.8 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293055.1_33723001_1 - 0.0001 21.5 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293055.1_33723001_1 - 0.0017 17.3 0.0 0.0034 16.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293055.1_33723001_1 - 0.0019 17.9 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293055.1_33723001_1 - 0.0019 18.2 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293055.1_33723001_1 - 0.0027 18.1 0.2 0.021 15.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.9 001293055.1_33723001_1 - 0.0069 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.19 001293055.1_33723001_1 - 0.0069 15.6 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.14 001293055.1_33723001_1 - 0.008 15.5 0.1 0.14 11.4 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein ATPase PF06745.11 001293055.1_33723001_1 - 0.0086 15.3 0.0 0.025 13.8 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.4 001293055.1_33723001_1 - 0.021 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293055.1_33723001_1 - 0.024 14.7 3.4 0.055 13.6 3.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293055.1_33723001_1 - 0.026 14.1 0.1 0.11 12.1 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293055.1_33723001_1 - 0.03 13.9 0.0 0.081 12.5 0.0 1.8 1 1 1 2 2 2 0 AAA domain TsaE PF02367.15 001293055.1_33723001_1 - 0.047 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293055.1_33723001_1 - 0.051 12.5 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.4 001293055.1_33723001_1 - 0.055 12.9 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.4 001293055.1_33723001_1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.11 001293055.1_33723001_1 - 0.058 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.20 001293055.1_33723001_1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.4 001293055.1_33723001_1 - 0.073 12.7 0.4 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.4 001293055.1_33723001_1 - 0.093 13.0 0.5 0.51 10.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.10 001293055.1_33723001_1 - 0.12 11.5 0.0 0.33 10.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.4 001293055.1_33723001_1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.10 001293055.1_33723001_1 - 0.24 11.3 3.5 1.3 8.9 0.9 2.7 3 0 0 3 3 3 0 Laminin Domain II MscS_porin PF12795.5 001293055.1_33723001_1 - 4.4 6.6 11.6 6.8 6.0 11.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Orn_Arg_deC_N PF02784.14 001301800.1_33728001_1 - 8.9e-65 218.4 0.1 1.1e-64 218.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301800.1_33728001_1 - 2.3e-22 79.0 0.0 4.3e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291764.1_33728001_1 - 8.9e-65 218.4 0.1 1.1e-64 218.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291764.1_33728001_1 - 4.3e-22 78.2 0.0 8e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001293788.1_33724001_3 - 3.5e-67 226.3 0.0 4.3e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293788.1_33724001_3 - 1.3e-20 73.4 0.0 2.2e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293788.1_33724001_3 - 0.0003 20.1 0.0 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001291773.1_41229001_3 - 7.4e-64 215.4 0.1 9.5e-64 215.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291773.1_41229001_3 - 1.2e-23 83.2 0.0 2e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001294180.1_41224001_1 - 1.8e-68 230.5 0.0 2.3e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001294180.1_41224001_1 - 2.1e-17 63.1 0.0 3.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001294180.1_41224001_1 - 0.00017 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001301806.1_41229001_2 - 7.8e-64 215.3 0.1 1e-63 215.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301806.1_41229001_2 - 1.2e-23 83.1 0.0 2.1e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301807.1_41229001_3 - 7.4e-64 215.4 0.1 9.5e-64 215.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301807.1_41229001_3 - 6.6e-24 84.0 0.0 1.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF5032 PF16435.3 001301807.1_41229001_3 - 0.057 12.8 0.1 0.098 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) Asp_protease_2 PF13650.4 001291365.1_41226001_1 - 0.0011 19.5 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291365.1_41226001_1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291365.1_41226001_1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291365.1_41226001_2 - 1.9e-16 60.0 0.0 3.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.3 001291365.1_41226001_2 - 9.3e-11 41.5 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001291365.1_41226001_2 - 0.00027 20.4 0.3 0.00069 19.1 0.3 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.21 001291365.1_41226001_2 - 0.027 14.4 1.8 0.074 13.0 1.8 1.8 1 0 0 1 1 1 0 Zinc knuckle COX17 PF05051.11 001291365.1_41226001_3 - 4.2 7.7 7.4 1.5 9.1 0.7 2.6 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DED PF01335.19 001114360.1_32323001_1 - 4.4e-38 129.3 20.3 1.2e-21 76.6 4.7 2.8 2 0 0 2 2 2 2 Death effector domain Peptidase_C14 PF00656.20 001114360.1_32323001_1 - 4.1e-31 108.7 0.3 7.6e-31 107.8 0.1 1.6 2 0 0 2 2 2 1 Caspase domain Orn_Arg_deC_N PF02784.14 001291426.2_32325001_1 - 9.1e-62 208.6 0.1 1.2e-61 208.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291426.2_32325001_1 - 1.5e-24 86.0 0.0 2.8e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain RRM_1 PF00076.20 001172361.1_32326001_1 - 9.9e-07 28.4 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.5 001172361.1_32326001_1 - 0.032 14.6 49.8 0.068 13.6 49.8 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term CD4-extracel PF09191.8 001099290.1_32325001_2 - 8.3e-31 106.5 1.3 2e-30 105.2 0.0 2.3 3 0 0 3 3 3 1 CD4, extracellular ig PF00047.23 001099290.1_32325001_2 - 5.6e-20 71.2 2.9 7.8e-13 48.3 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.4 001099290.1_32325001_2 - 3.4e-15 56.3 0.8 2.1e-05 24.9 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Tcell_CD4_C PF12104.6 001099290.1_32325001_2 - 3.9e-15 55.3 5.5 1.3e-14 53.7 5.5 1.9 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region V-set PF07686.15 001099290.1_32325001_2 - 8.6e-12 45.1 3.1 1.4e-10 41.2 0.2 3.2 2 1 1 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.14 001099290.1_32325001_2 - 1.3e-10 41.1 0.2 3.8e-06 26.8 0.1 3.0 1 1 1 2 2 2 2 Immunoglobulin I-set domain C2-set PF05790.13 001099290.1_32325001_2 - 9.5e-10 38.4 8.0 8.3e-06 25.8 0.4 3.5 3 0 0 3 3 3 2 Immunoglobulin C2-set domain Ig_2 PF13895.4 001099290.1_32325001_2 - 2.5e-09 37.2 0.3 0.00086 19.5 0.0 3.6 2 1 1 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.3 001099290.1_32325001_2 - 0.0008 19.3 0.1 0.74 9.8 0.0 3.6 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 001099290.1_32325001_2 - 0.0048 17.0 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 7tm_3 PF00003.20 001099541.1_32325001_1 - 2.7e-65 220.3 18.9 4.3e-65 219.7 18.9 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099541.1_32325001_1 - 2.1e-52 178.3 0.2 3.3e-52 177.6 0.2 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099541.1_32325001_1 - 1.7e-16 59.7 13.1 3.6e-16 58.7 13.1 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.16 001099541.1_32325001_1 - 0.36 11.1 9.3 0.84 10.0 5.7 2.7 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region DUF2157 PF09925.7 001099541.1_32325001_1 - 0.59 9.8 4.5 7.4 6.2 0.6 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Ephrin_rec_like PF07699.11 001099541.1_32325001_1 - 2.2 8.0 12.4 0.22 11.2 4.9 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like MHC_I_C PF06623.9 001246247.1_32324001_1 - 1.3e-05 24.8 1.2 2.9e-05 23.8 1.2 1.5 1 0 0 1 1 1 1 MHC_I C-terminus MHC_I PF00129.16 001246247.1_32324001_2 - 4.5e-64 215.2 1.7 6.2e-64 214.7 1.7 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001246247.1_32324001_2 - 1.5e-15 57.3 0.0 3.7e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.10 001246247.1_32324001_2 - 0.026 14.5 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain ig PF00047.23 001246247.1_32324001_2 - 0.1 12.6 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain 7tm_3 PF00003.20 001099580.1_32326001_1 - 5.2e-62 209.6 29.0 1e-61 208.6 29.0 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099580.1_32326001_1 - 2.1e-40 138.8 0.0 3.4e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099580.1_32326001_1 - 9.9e-19 66.9 13.2 2.4e-18 65.7 13.2 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099580.1_32326001_1 - 0.0051 16.4 5.3 0.014 15.0 5.3 1.7 1 0 0 1 1 1 1 Putative ephrin-receptor like 7tm_3 PF00003.20 001099582.1_32326001_1 - 1.6e-61 208.0 29.9 2.9e-61 207.1 29.9 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099582.1_32326001_1 - 5.1e-44 150.7 0.0 6.7e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099582.1_32326001_1 - 3.3e-17 62.0 13.6 3.3e-17 62.0 13.6 1.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR SP2 PF03014.12 001099582.1_32326001_1 - 0.084 10.8 0.1 0.15 9.9 0.1 1.3 1 0 0 1 1 1 0 Structural protein 2 Ephrin_rec_like PF07699.11 001099582.1_32326001_1 - 0.084 12.5 5.3 0.14 11.8 4.4 1.8 1 1 0 1 1 1 0 Putative ephrin-receptor like TNFR_c6 PF00020.16 001099582.1_32326001_1 - 6 7.2 9.0 22 5.5 3.9 2.8 1 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region 7tm_3 PF00003.20 001102435.1_32326001_1 - 5.5e-62 209.5 30.8 1.2e-61 208.4 29.2 2.3 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102435.1_32326001_1 - 1.6e-45 155.6 0.1 2.2e-45 155.1 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102435.1_32326001_1 - 1.5e-17 63.2 11.8 3e-17 62.2 11.8 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001102435.1_32326001_1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Asp_protease_2 PF13650.4 001291338.1_52729001_1 - 0.00035 21.1 0.0 0.00058 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291338.1_52729001_1 - 0.017 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291338.1_52729001_1 - 0.056 13.9 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291338.1_52729001_2 - 1.3e-15 57.3 2.0 1.1e-14 54.3 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291338.1_52729001_2 - 9.7e-15 54.3 0.0 1.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291338.1_52729001_2 - 0.00041 20.1 2.5 0.00069 19.4 2.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291338.1_52729001_2 - 0.0016 18.0 0.2 0.0049 16.4 0.2 1.9 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291338.1_52729001_2 - 0.0019 18.2 2.9 0.0033 17.4 2.9 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CASP_C PF08172.10 001291338.1_52729001_2 - 0.0079 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 CASP C terminal bZIP_1 PF00170.19 001291338.1_52729001_2 - 0.018 15.0 2.0 0.058 13.4 2.0 1.9 1 0 0 1 1 1 0 bZIP transcription factor CENP-H PF05837.10 001291338.1_52729001_2 - 0.088 13.1 3.3 0.18 12.1 3.3 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SR-25 PF10500.7 001291338.1_52729001_2 - 0.093 12.2 2.2 0.25 10.8 2.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.21 001291338.1_52729001_2 - 0.11 12.5 2.2 0.35 10.9 2.2 2.0 1 0 0 1 1 1 0 Zinc knuckle SHE3 PF17078.3 001291338.1_52729001_2 - 0.12 11.9 4.5 0.23 11.0 4.5 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 IncA PF04156.12 001291338.1_52729001_2 - 0.15 11.7 4.0 0.26 10.9 4.0 1.3 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.6 001291338.1_52729001_2 - 0.24 10.5 2.0 0.4 9.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.10 001291338.1_52729001_2 - 0.27 11.5 8.6 0.58 10.5 8.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB TolA_bind_tri PF16331.3 001291338.1_52729001_2 - 0.28 11.1 3.9 0.53 10.3 3.9 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Spc7 PF08317.9 001291338.1_52729001_2 - 0.36 9.5 4.8 0.6 8.8 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291338.1_52729001_2 - 0.37 11.3 3.5 0.9 10.1 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.6 001291338.1_52729001_2 - 0.38 10.6 5.5 0.7 9.8 5.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.13 001291338.1_52729001_2 - 1.2 8.8 5.3 3 7.5 5.3 1.7 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291338.1_52729001_2 - 1.6 8.7 6.8 3.7 7.5 6.8 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291338.1_52729001_2 - 2.1 8.9 5.0 4.8 7.7 5.0 1.5 1 0 0 1 1 1 0 SlyX RCDG1 PF15725.3 001291338.1_52729001_2 - 2.3 8.6 9.1 6 7.2 9.1 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Orn_Arg_deC_N PF02784.14 001291757.1_52729001_2 - 9.9e-64 215.0 0.1 1.3e-63 214.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291757.1_52729001_2 - 2.9e-24 85.1 0.0 4.9e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301798.1_52729001_3 - 9.3e-64 215.1 0.1 1.2e-63 214.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301798.1_52729001_3 - 2.8e-24 85.2 0.0 4.7e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Agouti PF05039.10 001287858.1_52721001_1 - 3.3e-15 56.4 4.2 5.5e-15 55.7 4.2 1.4 1 0 0 1 1 1 1 Agouti protein ETRAMP PF09716.8 001287858.1_52721001_1 - 0.009 15.9 1.4 0.014 15.4 1.4 1.4 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Chordopox_A30L PF06015.10 001287858.1_52721001_1 - 0.35 10.6 4.3 0.53 10.0 4.3 1.3 1 0 0 1 1 1 0 Chordopoxvirus A30L protein OAD_gamma PF04277.11 001287858.1_52721001_1 - 0.4 11.2 1.4 2.2 8.8 2.3 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ERCC3_RAD25_C PF16203.3 001246794.1_14225001_1 - 1.7e-125 417.1 1.6 2.9e-125 416.3 1.6 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.4 001246794.1_14225001_1 - 2.9e-39 134.0 0.0 9.3e-39 132.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001246794.1_14225001_1 - 7e-16 58.6 0.0 2.1e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.29 001246794.1_14225001_1 - 2.1e-10 40.8 0.1 5.6e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.21 001246794.1_14225001_1 - 0.0022 16.6 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.27 001246794.1_14225001_1 - 0.0025 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2748 PF10871.6 001246794.1_14225001_1 - 0.013 14.0 0.0 0.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2748) LRR_9 PF14580.4 001282002.1_14222001_3 - 2.9e-12 46.3 0.1 2.1e-11 43.5 0.0 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.4 001282002.1_14222001_3 - 5.6e-07 29.1 2.5 5.6e-07 29.1 2.5 2.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.5 001282002.1_14222001_3 - 1.4e-05 25.2 10.6 0.00055 20.1 0.4 3.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001282002.1_14222001_3 - 2.7 8.7 8.0 64 4.5 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Ald_Xan_dh_C2 PF02738.16 001291944.1_14228001_1 - 1.2e-183 611.4 0.1 1.6e-183 611.0 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001291944.1_14228001_1 - 1.1e-43 148.8 0.0 2.8e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001291944.1_14228001_1 - 5e-33 113.6 0.7 9.4e-33 112.7 0.7 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001291944.1_14228001_1 - 1.8e-29 101.8 0.0 5.1e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.18 001291944.1_14228001_1 - 7.4e-29 99.4 1.1 1.8e-28 98.2 1.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain MHC_I PF00129.16 001243997.1_14223001_1 - 1.9e-85 284.8 0.1 3e-85 284.1 0.1 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001243997.1_14223001_1 - 5.5e-16 58.7 0.1 1.1e-15 57.8 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001243997.1_14223001_1 - 0.00058 20.3 0.5 0.014 15.8 0.1 2.7 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.23 001243997.1_14223001_1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001243997.1_14223001_1 - 0.0045 16.9 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain DUF4448 PF14610.4 001243997.1_14223001_1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3377 PF11857.6 001243997.1_14223001_1 - 0.16 11.7 1.3 19 5.1 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) zf-H2C2_2 PF13465.4 001246447.2_39724001_2 - 8.5e-69 225.0 86.9 4.3e-10 39.4 0.9 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.24 001246447.2_39724001_2 - 7.3e-62 202.4 93.6 1.2e-07 31.7 0.7 12.8 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001246447.2_39724001_2 - 4e-31 104.8 87.1 0.00082 19.9 1.8 12.3 12 0 0 12 12 12 10 C2H2-type zinc finger KRAB PF01352.25 001246447.2_39724001_2 - 2.6e-23 81.3 0.7 5.4e-23 80.3 0.7 1.6 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001246447.2_39724001_2 - 1.3e-14 53.6 76.5 0.00019 21.1 2.3 11.1 11 0 0 11 11 11 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001246447.2_39724001_2 - 1.8e-11 43.8 59.4 0.0027 17.7 2.2 8.0 5 2 4 9 9 9 6 Zinc ribbon domain zf-trcl PF13451.4 001246447.2_39724001_2 - 0.0033 17.1 48.8 0.5 10.2 1.8 10.8 10 1 0 10 10 10 3 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.3 001246447.2_39724001_2 - 0.0039 17.8 47.5 0.067 13.8 0.6 6.9 1 1 8 9 9 9 6 zinc-ribbon family zf-C2H2_jaz PF12171.6 001246447.2_39724001_2 - 0.01 16.0 57.3 0.069 13.4 0.7 10.2 10 0 0 10 10 10 3 Zinc-finger double-stranded RNA-binding CpXC PF14353.4 001246447.2_39724001_2 - 0.18 11.7 41.6 2.1 8.2 0.1 10.1 5 3 1 8 8 8 0 CpXC protein DUF3268 PF11672.6 001246447.2_39724001_2 - 0.46 10.7 40.2 0.43 10.8 1.0 6.5 3 1 7 10 10 10 0 zinc-finger-containing domain zinc_ribbon_9 PF14369.4 001246447.2_39724001_2 - 1.2 9.3 0.0 1.2 9.3 0.0 7.8 8 2 0 8 8 8 0 zinc-ribbon ADK_lid PF05191.12 001246447.2_39724001_2 - 1.3 9.0 33.7 3.9 7.4 0.7 8.6 3 3 5 8 8 8 0 Adenylate kinase, active site lid Ank PF00023.28 027417.1_26225120_2 - 0.0026 18.0 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.4 027417.1_26225120_2 - 0.057 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.5 027417.1_26225120_2 - 0.065 13.7 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) GBP_PSP PF02425.13 037685.1_43529120_3 - 0.71 9.4 2.8 19 4.9 2.4 2.8 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide P33MONOX PF15302.4 045552.1_49822120_3 - 9.6e-13 48.3 0.1 1.4e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 P33 mono-oxygenase NDK PF00334.17 001204753.1_37622001_2 - 4.7e-56 188.4 0.0 5.5e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PRNT PF15174.4 038114.1_43525120_1 - 4.4e-34 116.1 4.0 9e-34 115.1 4.0 1.6 1 0 0 1 1 1 1 Prion-related protein testis-specific V1R PF03402.12 001167270.1_37922001_1 - 1.2e-28 100.3 16.3 1.6e-28 99.9 16.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167270.1_37922001_1 - 3.6e-08 32.7 22.7 4.4e-08 32.5 22.7 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Asp PF00026.21 001285562.1_09023001_1 - 3.6e-94 315.6 0.0 4.5e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease A1_Propeptide PF07966.10 001285562.1_09023001_1 - 7.8e-14 51.1 0.8 1.3e-13 50.3 0.8 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_N PF14543.4 001285562.1_09023001_1 - 3.9e-10 40.1 0.2 4.6e-08 33.4 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MHC_I PF00129.16 002155.1_45722120_1 - 5.7e-35 120.4 0.2 7.3e-35 120.0 0.2 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I PF00129.16 002155.1_45722120_2 - 2.8e-41 140.9 0.8 3.7e-41 140.5 0.8 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Globin PF00042.20 001286594.1_40021001_1 - 1.5e-29 102.6 0.0 8.6e-29 100.2 0.0 1.8 2 0 0 2 2 2 1 Globin Globin PF00042.20 001286593.1_40022001_3 - 3.6e-29 101.4 0.1 9.9e-29 100.0 0.0 1.8 2 0 0 2 2 2 1 Globin RNase_H PF00075.22 001286029.1_35723001_2 - 7.4e-27 94.2 0.0 8.2e-19 68.1 0.0 2.3 1 1 1 2 2 2 2 RNase H Cauli_VI PF01693.14 001286029.1_35723001_2 - 1.9e-19 69.5 1.2 3.2e-19 68.8 1.2 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001286029.1_35723001_2 - 0.024 14.2 0.0 0.056 13.0 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase-like RNase_H PF00075.22 001285868.1_36523001_1 - 2.1e-45 154.3 0.0 3.4e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285868.1_36523001_1 - 1.5e-18 66.7 4.8 3.2e-18 65.6 2.9 2.3 2 0 0 2 2 2 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285868.1_36523001_1 - 0.00064 19.3 0.0 0.0021 17.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase-like RNase_H PF00075.22 001286019.1_36222001_1 - 7.8e-45 152.4 0.0 1e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001286019.1_36222001_1 - 3.5e-18 65.5 1.9 7.6e-18 64.4 1.9 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001286019.1_36222001_1 - 0.00011 21.7 0.0 0.00045 19.8 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like RNase_H PF00075.22 001285889.1_20322001_1 - 1.3e-45 155.0 0.3 7.6e-45 152.5 0.0 1.9 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.14 001285889.1_20322001_1 - 2.4e-19 69.2 1.3 4.6e-19 68.3 1.3 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285889.1_20322001_1 - 0.0011 18.6 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like RNase_H PF00075.22 001285996.1_27023001_1 - 9.1e-33 113.3 0.0 2.3e-32 112.1 0.0 1.6 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.14 001285996.1_27023001_1 - 5.5e-19 68.1 0.9 5.5e-19 68.1 0.9 1.7 2 0 0 2 2 2 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285996.1_27023001_1 - 0.005 16.4 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.22 001285876.1_48822001_1 - 4.1e-33 114.5 0.0 6.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285876.1_48822001_1 - 8.1e-07 29.1 1.1 1.7e-06 28.1 1.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285876.1_48822001_1 - 0.065 12.8 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like ODC_AZ PF02100.15 001290366.1_24222001_2 - 6.9e-14 51.7 0.0 9.9e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme V1R PF03402.12 001166721.1_32922001_1 - 5.3e-20 72.0 7.8 7.3e-20 71.6 7.8 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001166721.1_32922001_1 - 7.6e-12 44.8 12.3 1.1e-11 44.3 12.3 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001166721.1_32922001_1 - 1.2e-05 24.5 12.6 1.6e-05 24.2 12.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Vpu PF00558.17 001166721.1_32922001_1 - 0.033 13.8 0.4 0.88 9.3 0.1 2.3 2 0 0 2 2 2 0 Vpu protein CEBP_ZZ PF16366.3 001166721.1_32922001_1 - 0.11 12.7 2.3 2.3 8.4 0.1 2.7 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain 7tm_4 PF13853.4 146292.1_32922001_1 - 4.2e-58 197.2 16.7 5e-58 196.9 16.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146292.1_32922001_1 - 5.4e-26 91.3 18.4 1.4e-25 89.9 18.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 146292.1_32922001_1 - 1.8e-06 27.4 18.1 5.2e-06 25.9 18.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 146562.1_32922001_1 - 9.1e-52 176.4 21.9 1.1e-51 176.1 21.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146562.1_32922001_1 - 6.9e-24 84.4 21.0 1.7e-23 83.1 21.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 146562.1_32922001_1 - 6.3e-07 28.9 19.2 9.7e-07 28.3 19.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx RIC1 PF07064.11 146562.1_32922001_1 - 0.025 13.9 1.3 0.046 13.0 1.3 1.4 1 0 0 1 1 1 0 RIC1 SLC3A2_N PF16028.3 146562.1_32922001_1 - 0.088 12.2 4.4 0.47 9.9 0.1 2.7 2 1 1 3 3 3 0 Solute carrier family 3 member 2 N-terminus Orn_Arg_deC_N PF02784.14 001291477.1_35728001_2 - 4.7e-64 216.1 0.1 5.9e-64 215.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291477.1_35728001_2 - 2.5e-24 85.3 0.0 4.8e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301735.1_24229001_3 - 1.5e-63 214.4 0.1 1.8e-63 214.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301735.1_24229001_3 - 2.9e-24 85.2 0.0 5.2e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301742.1_36529001_1 - 1.9e-63 214.1 0.1 2.4e-63 213.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301742.1_36529001_1 - 3.9e-24 84.7 0.0 7.2e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301748.1_48829001_3 - 7.9e-63 212.0 0.1 1e-62 211.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301748.1_48829001_3 - 1.1e-23 83.2 0.0 1.9e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301749.1_27026001_1 - 5.6e-63 212.5 0.1 7.3e-63 212.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301749.1_27026001_1 - 1.5e-23 82.9 0.0 3e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301751.1_20329001_2 - 1.6e-64 217.6 0.2 2e-64 217.3 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301751.1_20329001_2 - 4.3e-24 84.6 0.0 7.7e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291515.1_36529001_3 - 2e-63 214.0 0.1 2.5e-63 213.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291515.1_36529001_3 - 4.1e-24 84.7 0.0 7.6e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291520.1_48829001_2 - 8.4e-63 212.0 0.1 1.1e-62 211.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291520.1_48829001_2 - 1.2e-23 83.2 0.0 2e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291551.1_27026001_3 - 6.2e-63 212.4 0.1 8e-63 212.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291551.1_27026001_3 - 1.6e-23 82.7 0.0 3.2e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291554.1_20329001_3 - 1.6e-64 217.6 0.2 2.1e-64 217.2 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291554.1_20329001_3 - 4.4e-24 84.6 0.0 8.1e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291720.1_06428001_1 - 9.8e-64 215.0 0.1 1.2e-63 214.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291720.1_06428001_1 - 7.1e-24 83.9 0.0 1.2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291724.1_40029001_3 - 4.5e-64 216.1 0.1 5.7e-64 215.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291724.1_40029001_3 - 1.1e-23 83.3 0.0 1.8e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291763.1_28329001_2 - 2.9e-63 213.4 0.1 3.8e-63 213.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291763.1_28329001_2 - 8.4e-24 83.7 0.0 1.5e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291770.1_12129001_2 - 5.1e-64 215.9 0.2 6.5e-64 215.6 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291770.1_12129001_2 - 6.7e-22 77.6 0.0 1.2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301799.1_28329001_3 - 2.8e-63 213.5 0.1 3.6e-63 213.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301799.1_28329001_3 - 8e-24 83.7 0.0 1.4e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301801.1_12129001_3 - 4.9e-64 216.0 0.2 6.2e-64 215.7 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301801.1_12129001_3 - 6.3e-22 77.6 0.0 1.2e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291771.1_20626001_3 - 1.8e-63 214.2 0.1 2.3e-63 213.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291771.1_20626001_3 - 2.4e-23 82.2 0.0 4.7e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301814.1_28829001_2 - 1e-62 211.7 0.1 1.3e-62 211.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301814.1_28829001_2 - 4.4e-24 84.6 0.0 7.7e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291788.1_28829001_1 - 1.1e-62 211.6 0.1 1.4e-62 211.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291788.1_28829001_1 - 4.7e-24 84.5 0.0 8.1e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain MHC_I PF00129.16 001279231.1_39623001_1 - 4.6e-94 312.9 0.4 6.6e-94 312.4 0.4 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001279231.1_39623001_1 - 2.7e-17 62.9 0.0 6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001279231.1_39623001_1 - 9e-17 60.6 8.1 1.7e-16 59.7 8.1 1.5 1 0 0 1 1 1 1 MHC_I C-terminus C2-set_2 PF08205.10 001279231.1_39623001_1 - 0.0016 18.3 1.6 0.0017 18.3 0.1 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001279231.1_39623001_1 - 0.0043 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain DUF202 PF02656.13 001279231.1_39623001_1 - 0.03 14.6 0.1 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) bZIP_1 PF00170.19 001246812.1_14223001_1 - 6.8e-17 61.2 15.5 1e-16 60.6 15.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001246812.1_14223001_1 - 1.6e-06 27.9 13.5 1.6e-06 27.9 13.5 1.6 1 1 0 1 1 1 1 Basic region leucine zipper DUF4407 PF14362.4 001246812.1_14223001_1 - 0.0071 15.6 2.8 0.0099 15.1 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Fez1 PF06818.13 001246812.1_14223001_1 - 0.095 13.0 10.0 0.13 12.5 10.0 1.1 1 0 0 1 1 1 0 Fez1 AAA_13 PF13166.4 001246812.1_14223001_1 - 0.097 11.2 10.3 0.12 10.9 10.3 1.0 1 0 0 1 1 1 0 AAA domain Taxilin PF09728.7 001246812.1_14223001_1 - 0.099 11.8 13.1 0.18 10.9 13.1 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF4653 PF15546.4 001246812.1_14223001_1 - 0.1 12.1 1.8 0.14 11.7 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) OmpH PF03938.12 001246812.1_14223001_1 - 0.11 12.4 7.7 0.17 11.8 7.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.10 001246812.1_14223001_1 - 0.14 12.0 6.7 0.22 11.4 6.7 1.2 1 0 0 1 1 1 0 Laminin Domain II CENP-F_leu_zip PF10473.7 001246812.1_14223001_1 - 0.23 11.4 11.5 0.37 10.7 11.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.6 001246812.1_14223001_1 - 0.25 10.5 8.3 0.37 9.9 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.12 001246812.1_14223001_1 - 0.68 9.6 9.7 1 9.0 9.7 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.10 001246812.1_14223001_1 - 0.72 9.1 10.8 1 8.5 10.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_Maf PF03131.15 001246812.1_14223001_1 - 0.77 10.2 8.6 1.2 9.6 8.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Mnd1 PF03962.13 001246812.1_14223001_1 - 1.7 8.4 13.6 2.7 7.7 13.6 1.2 1 0 0 1 1 1 0 Mnd1 family Baculo_F PF12259.6 001246812.1_14223001_1 - 1.8 6.9 4.5 2.3 6.5 4.5 1.1 1 0 0 1 1 1 0 Baculovirus F protein ZapB PF06005.10 001246812.1_14223001_1 - 1.9 8.8 14.6 0.082 13.2 4.4 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF724 PF05266.12 001246812.1_14223001_1 - 2.8 7.6 14.6 2.4 7.8 12.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Cnn_1N PF07989.9 001246812.1_14223001_1 - 4 7.5 11.9 13 5.8 11.9 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF342 PF03961.11 001246812.1_14223001_1 - 5.1 5.5 9.3 6.7 5.1 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PNRC PF15365.4 001205202.1_37925001_1 - 1.6e-09 38.0 6.5 1.6e-09 38.0 6.5 2.8 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator Rsm22 PF09243.8 001082160.1_37923001_1 - 2.2 7.3 4.5 3.5 6.7 4.5 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RRM_1 PF00076.20 001082160.1_37923001_2 - 7.7e-29 99.2 1.2 2.6e-14 52.7 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001082160.1_37923001_2 - 7.8e-08 31.8 0.0 0.0075 15.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001082160.1_37923001_2 - 1.9e-07 30.7 0.0 0.001 18.7 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.4 001082160.1_37923001_2 - 0.0081 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) UNC-79 PF14776.4 001306216.1_37921001_2 - 0.04 12.5 0.0 0.047 12.3 0.0 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Ribosomal_L27A PF00828.17 001290589.1_39922001_3 - 2e-24 86.5 0.1 3e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_L_2 PF13656.4 003655.3_26229120_1 - 4.9e-23 80.6 0.1 9.3e-23 79.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain C2 PF00168.28 003655.3_26229120_1 - 4.8e-13 49.2 0.0 8.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain RNA_pol_L PF01193.22 003655.3_26229120_1 - 1.2e-06 27.8 0.0 1.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain C2 PF00168.28 003655.3_26229120_2 - 3.4e-08 33.6 0.0 5.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain HTH_37 PF13744.4 003655.3_26229120_2 - 0.053 13.3 0.2 0.09 12.6 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S26e PF01283.17 001267787.1_29624001_2 - 2e-21 76.3 2.3 3.5e-21 75.5 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S26e RNA_pol_Rpb4 PF03874.14 001267787.1_29624001_3 - 6.2e-24 84.5 6.0 8.5e-24 84.1 6.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Tfb4 PF03850.12 001267787.1_29624001_3 - 0.064 12.5 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 IIGP PF05049.11 001289892.1_39624001_2 - 1.8e-64 218.0 0.0 2.3e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Arrestin_N PF00339.27 001173086.1_09924001_3 - 1.6e-37 128.7 0.1 6.7e-34 116.9 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 001173086.1_09924001_3 - 3.3e-22 79.2 0.7 4.9e-22 78.6 0.7 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Transglut_C PF00927.20 001173086.1_09924001_3 - 0.026 14.5 0.6 0.053 13.5 0.6 1.4 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Collagen PF01391.16 001323779.1_20929001_2 - 6.5e-177 573.4 721.5 9.1e-12 44.4 28.1 20.3 2 1 12 15 15 15 12 Collagen triple helix repeat (20 copies) COLFI PF01410.16 001323779.1_20929001_2 - 5.7e-112 372.6 0.4 7.2e-112 372.2 0.4 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.16 001323779.1_20929001_2 - 2.9e-10 40.1 14.9 6.5e-10 39.0 14.9 1.6 1 0 0 1 1 1 1 von Willebrand factor type C domain VWA PF00092.26 001290868.1_07327001_1 - 2.7e-86 288.1 0.0 8.1e-29 101.0 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.16 001290868.1_07327001_1 - 1.4e-51 171.9 200.0 5.8e-09 35.4 28.2 7.4 1 1 6 7 7 7 7 Collagen triple helix repeat (20 copies) VWA_2 PF13519.4 001290868.1_07327001_1 - 3.8e-37 127.1 0.0 3.7e-15 56.4 0.0 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_CoxE PF05762.12 001290868.1_07327001_1 - 0.0016 17.7 0.0 0.31 10.3 0.0 3.2 3 0 0 3 3 3 1 VWA domain containing CoxE-like protein YcaO PF02624.14 001290868.1_07327001_1 - 0.19 10.9 0.1 0.39 9.8 0.1 1.4 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Sedlin_N PF04628.11 001290579.1_39922001_3 - 6.8e-35 119.9 0.7 8.4e-35 119.6 0.7 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.10 001290579.1_39922001_3 - 1.2e-09 38.1 0.2 1.5e-09 37.8 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family Aldose_epim PF01263.18 001290593.1_39923001_3 - 6.7e-103 344.0 0.2 7.6e-103 343.8 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_transf_7C PF02709.12 001290593.1_39923001_3 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase LRR_8 PF13855.4 001305947.1_10826001_3 - 1.6e-60 200.6 60.0 2.2e-13 49.6 5.0 10.9 6 2 3 10 10 10 9 Leucine rich repeat TIR PF01582.18 001305947.1_10826001_3 - 8.7e-36 123.2 0.8 1.3e-35 122.6 0.8 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001305947.1_10826001_3 - 1.9e-27 94.7 65.9 5.7e-05 23.2 2.8 12.2 6 4 7 13 13 13 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001305947.1_10826001_3 - 2.7e-14 53.1 0.7 1.2e-06 28.4 0.2 4.2 3 2 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_1 PF00560.31 001305947.1_10826001_3 - 9.8e-11 40.4 48.8 0.31 11.5 0.7 15.8 14 2 1 15 15 15 4 Leucine Rich Repeat LRR_9 PF14580.4 001305947.1_10826001_3 - 8.3e-10 38.3 21.5 0.018 14.4 0.7 6.1 2 2 4 6 6 6 5 Leucine-rich repeat LRR_6 PF13516.4 001305947.1_10826001_3 - 1.5e-06 27.7 40.6 1.9 8.6 0.3 13.5 14 0 0 14 14 14 4 Leucine Rich repeat TIR_2 PF13676.4 001305947.1_10826001_3 - 4.8e-06 26.7 0.0 9.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRRCT PF01463.22 001305947.1_10826001_3 - 0.047 14.1 0.1 3.4 8.3 0.0 3.1 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain LRR_8 PF13855.4 001305967.1_10826001_2 - 8.2e-79 259.2 94.2 3.9e-12 45.6 6.0 10.7 7 3 2 10 10 10 10 Leucine rich repeat LRR_4 PF12799.5 001305967.1_10826001_2 - 1e-34 117.7 99.1 5.5e-05 23.3 6.4 12.9 6 2 5 14 14 14 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001305967.1_10826001_2 - 1.4e-21 76.6 26.6 8.9e-06 25.6 1.2 5.8 3 2 3 6 6 6 5 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001305967.1_10826001_2 - 3e-12 46.3 34.5 7.4e-06 25.4 2.1 7.5 2 1 6 8 8 8 5 Leucine-rich repeat LRR_1 PF00560.31 001305967.1_10826001_2 - 2e-10 39.5 84.2 1.6 9.4 0.1 20.7 21 1 0 21 21 21 7 Leucine Rich Repeat TIR PF01582.18 001305967.1_10826001_2 - 2.5e-09 37.1 0.8 4.5e-09 36.2 0.8 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001305967.1_10826001_2 - 5.6e-05 22.7 92.7 0.34 10.9 0.1 18.4 19 0 0 19 19 19 7 Leucine Rich repeat LRRNT PF01462.16 001305967.1_10826001_2 - 0.0037 16.7 0.2 0.013 15.0 0.2 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRRCT PF01463.22 001305967.1_10826001_2 - 0.011 16.1 0.1 0.049 14.1 0.1 2.3 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain TIR_2 PF13676.4 001305967.1_10826001_2 - 0.034 14.4 0.1 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 TIR domain RHIM PF12721.5 001279226.1_39625001_1 - 3.7e-13 49.6 7.3 3.7e-13 49.6 7.3 3.7 3 1 0 3 3 3 1 RIP homotypic interaction motif TIR_2 PF13676.4 001279226.1_39625001_1 - 0.027 14.7 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 TIR domain bZIP_2 PF07716.13 001139449.1_39522001_1 - 3.2e-16 59.0 11.6 4.9e-16 58.4 11.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.19 001139449.1_39522001_1 - 0.0038 17.2 7.8 0.0064 16.4 7.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.15 001139449.1_39522001_1 - 0.66 10.4 7.8 1 9.8 7.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor 7tm_1 PF00001.19 001329794.1_11723001_1 - 9e-51 172.5 15.6 1.2e-50 172.1 15.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001329794.1_11723001_1 - 3.2e-11 43.0 19.4 4.2e-11 42.6 19.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001329794.1_11723001_1 - 0.0001 22.0 9.4 0.0001 22.0 9.4 1.5 2 0 0 2 2 2 1 Olfactory receptor CtIP_N PF10482.7 001280089.1_35726001_1 - 1.6e-53 179.8 21.8 8.3e-53 177.4 21.8 2.3 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain SAE2 PF08573.8 001280089.1_35726001_1 - 4.6e-05 24.4 0.5 4.6e-05 24.4 0.5 5.8 5 1 1 6 6 6 2 DNA repair protein endonuclease SAE2/CtIP C-terminus tRNA_SAD PF07973.12 001280089.1_35726001_2 - 0.095 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain LRR_8 PF13855.4 001290918.1_07326001_1 - 1.5e-56 187.9 69.9 1.4e-12 47.0 4.3 12.1 9 4 4 13 13 13 10 Leucine rich repeat TIR PF01582.18 001290918.1_07326001_1 - 1.3e-30 106.4 2.4 1.6e-30 106.1 1.3 1.7 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.5 001290918.1_07326001_1 - 2.1e-20 72.3 65.2 2.9e-05 24.2 2.9 12.0 5 2 8 14 14 14 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001290918.1_07326001_1 - 2.1e-11 43.7 6.6 1.2e-06 28.4 0.3 4.5 5 1 1 6 6 6 3 Leucine rich repeats (6 copies) TIR_2 PF13676.4 001290918.1_07326001_1 - 1.3e-06 28.5 0.0 9.7e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.4 001290918.1_07326001_1 - 4.9e-06 26.0 17.0 0.18 11.2 1.1 5.6 3 2 3 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.4 001290918.1_07326001_1 - 1.3e-05 24.7 45.1 1.6 8.9 0.2 14.1 16 0 0 16 16 16 3 Leucine Rich repeat LRR_1 PF00560.31 001290918.1_07326001_1 - 6.7e-05 22.7 54.4 0.29 11.6 0.0 14.8 14 4 0 14 14 14 3 Leucine Rich Repeat LRRCT PF01463.22 001290918.1_07326001_1 - 0.066 13.6 0.1 4.3 8.0 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain Dynamin_M PF01031.18 001280102.1_35724001_1 - 2.1e-87 292.8 9.8 2.1e-87 292.8 9.8 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.21 001280102.1_35724001_1 - 3.5e-50 170.2 2.3 3.8e-50 170.1 0.3 2.2 2 0 0 2 2 2 1 Dynamin family GED PF02212.16 001280102.1_35724001_1 - 1.9e-25 88.7 1.5 1.9e-25 88.7 1.5 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.21 001280102.1_35724001_1 - 0.00021 21.2 3.1 0.0017 18.3 0.6 3.3 2 2 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.4 001280102.1_35724001_1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.4 001280102.1_35724001_1 - 0.022 14.3 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.4 001280102.1_35724001_1 - 0.031 14.5 0.7 0.82 9.9 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Usher PF00577.18 001280102.1_35724001_1 - 0.12 11.0 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Outer membrane usher protein ABC_tran PF00005.25 001280102.1_35724001_1 - 0.21 11.9 3.6 0.24 11.8 0.0 2.7 2 1 0 2 2 2 0 ABC transporter PP_kinase_N PF13089.4 001280102.1_35724001_1 - 0.56 10.4 4.1 0.84 9.9 1.7 2.7 2 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain IL28A PF15177.4 001290171.1_44822001_1 - 6e-73 243.7 4.0 7.2e-73 243.5 4.0 1.1 1 0 0 1 1 1 1 Interleukin-28A Peptidase_C54 PF03416.17 001257887.1_29624001_3 - 1.4e-102 342.5 0.0 2.1e-102 341.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Dynamin_M PF01031.18 001290174.1_44825001_1 - 2.8e-84 282.6 15.2 2.8e-84 282.6 15.2 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.21 001290174.1_44825001_1 - 3.2e-50 170.3 0.0 3.2e-50 170.3 0.0 2.9 2 1 0 2 2 2 1 Dynamin family GED PF02212.16 001290174.1_44825001_1 - 1.5e-22 79.4 0.5 1.5e-22 79.4 0.5 2.6 3 0 0 3 3 2 1 Dynamin GTPase effector domain AAA_21 PF13304.4 001290174.1_44825001_1 - 0.0035 17.1 0.3 0.022 14.5 0.0 2.3 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.21 001290174.1_44825001_1 - 0.0043 17.0 4.6 0.0053 16.7 0.2 3.2 3 2 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.4 001290174.1_44825001_1 - 0.02 15.2 0.9 0.97 9.7 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.25 001290174.1_44825001_1 - 0.02 15.3 0.0 0.02 15.3 0.0 2.8 3 2 0 3 3 3 0 ABC transporter AAA_29 PF13555.4 001290174.1_44825001_1 - 0.021 14.4 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDT1_C PF16679.3 001290174.1_44825001_1 - 0.041 14.1 2.6 0.2 11.9 0.5 3.0 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain CHDNT PF08073.10 001290174.1_44825001_1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 CHDNT (NUC034) domain AAA_23 PF13476.4 001290174.1_44825001_1 - 0.24 11.7 23.9 0.98 9.8 10.4 3.7 3 1 0 3 3 3 0 AAA domain NYD-SP28_assoc PF14775.4 001290174.1_44825001_1 - 0.72 9.9 4.2 1.7 8.7 2.6 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain Cnd1 PF12717.5 001290174.1_44825001_1 - 1.1 9.1 6.1 1.1 9.1 1.6 2.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Mito_carr PF00153.25 001294326.1_06422001_1 - 1.2e-68 226.9 3.7 7.4e-25 86.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein APOC4 PF15119.4 001290577.1_39921001_2 - 2.9e-43 145.9 0.7 4e-43 145.5 0.7 1.2 1 0 0 1 1 1 1 Apolipoprotein C4 Ephrin PF00812.15 001290165.1_44823001_1 - 8.9e-43 145.5 0.0 2e-42 144.3 0.0 1.5 2 0 0 2 2 2 1 Ephrin TIR PF01582.18 001305972.1_10826001_1 - 1.8e-27 96.1 0.4 4.2e-27 94.9 0.4 1.6 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001305972.1_10826001_1 - 4.1e-21 74.4 35.9 1.1e-10 41.0 3.7 7.6 3 3 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.5 001305972.1_10826001_1 - 1e-18 66.9 43.4 1.4e-06 28.4 0.5 8.6 6 2 3 9 9 9 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001305972.1_10826001_1 - 5e-12 45.9 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001305972.1_10826001_1 - 4.3e-06 26.2 8.1 0.07 12.5 0.2 3.4 3 0 0 3 3 3 3 Leucine-rich repeat LRRCT PF01463.22 001305972.1_10826001_1 - 7.2e-06 26.0 0.0 2.3e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001305972.1_10826001_1 - 0.00061 19.8 29.2 8.9 7.1 0.1 11.1 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.4 001305972.1_10826001_1 - 0.001 18.8 25.2 2.9 8.1 0.0 9.6 10 0 0 10 10 10 2 Leucine Rich repeat Tautomerase PF01361.19 001305972.1_10826001_1 - 0.037 13.8 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Tautomerase enzyme LRR_8 PF13855.4 001279539.1_24225001_1 - 1.8e-23 81.9 40.5 1.9e-12 46.6 4.2 6.6 3 2 2 6 6 6 5 Leucine rich repeat TIR PF01582.18 001279539.1_24225001_1 - 2.5e-23 82.6 0.3 4.6e-23 81.8 0.3 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001279539.1_24225001_1 - 2.4e-16 59.4 46.5 1.9e-06 27.9 0.4 8.3 4 3 4 9 9 9 8 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001279539.1_24225001_1 - 2.3e-07 31.0 0.0 4.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001279539.1_24225001_1 - 3.6e-06 26.5 43.3 1.4 9.5 0.1 12.5 12 1 0 12 12 12 2 Leucine Rich Repeat LRR_6 PF13516.4 001279539.1_24225001_1 - 8.2e-06 25.3 30.3 3.9 7.7 0.0 10.7 11 0 0 11 11 11 4 Leucine Rich repeat LRRCT PF01463.22 001279539.1_24225001_1 - 0.00044 20.4 0.3 0.0046 17.3 0.0 2.8 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.4 001279539.1_24225001_1 - 0.0013 18.1 12.0 0.71 9.2 1.7 3.8 2 1 2 4 4 4 2 Leucine-rich repeat LRR_8 PF13855.4 001305889.1_29725001_1 - 3.9e-41 138.5 66.3 4.3e-11 42.3 0.4 10.5 5 4 7 12 12 12 11 Leucine rich repeat TIR PF01582.18 001305889.1_29725001_1 - 2.5e-33 115.2 0.8 4.2e-33 114.5 0.8 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001305889.1_29725001_1 - 9.2e-27 92.4 59.2 1.3e-05 25.2 4.8 11.8 7 2 6 13 13 13 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001305889.1_29725001_1 - 3.8e-10 39.4 20.2 3.7e-05 23.1 0.0 5.1 3 2 2 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.31 001305889.1_29725001_1 - 6.2e-10 38.0 52.5 0.17 12.4 0.1 15.6 14 2 0 14 14 14 3 Leucine Rich Repeat TIR_2 PF13676.4 001305889.1_29725001_1 - 2.5e-09 37.2 0.1 4.7e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001305889.1_29725001_1 - 8.5e-07 28.4 49.8 0.3 11.1 1.6 13.1 15 0 0 15 15 15 3 Leucine Rich repeat DUF1863 PF08937.9 001305889.1_29725001_1 - 0.00012 22.2 0.5 0.00055 20.1 0.5 2.0 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) Curto_V2 PF07325.9 001305889.1_29725001_1 - 0.16 11.7 0.3 0.46 10.2 0.3 1.7 1 0 0 1 1 1 0 Curtovirus V2 protein Exo_endo_phos PF03372.21 001290614.1_39923001_3 - 1e-12 48.2 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.4 001290614.1_39923001_3 - 0.0062 16.2 0.0 0.035 13.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Lipocalin PF00061.21 001287575.1_09021001_1 - 1.7e-15 57.4 1.7 1.8e-15 57.2 1.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001287575.1_09021001_1 - 1.2e-08 34.8 1.7 1.4e-08 34.6 1.7 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_4 PF13648.4 001287575.1_09021001_1 - 0.0029 18.4 1.2 0.0082 17.0 1.2 1.8 1 1 0 1 1 1 1 Lipocalin-like domain PARP PF00644.18 001279213.1_39626001_1 - 1.6e-21 76.7 6.2 1.9e-19 70.0 6.2 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.18 001279213.1_39626001_1 - 3.4e-15 56.2 3.6 1.7e-12 47.6 2.3 2.8 2 0 0 2 2 2 2 WWE domain ERbeta_N PF12497.6 001279251.1_10724001_1 - 1.4e-53 179.4 7.6 2.6e-53 178.5 7.6 1.5 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.28 001279251.1_10724001_1 - 1.2e-34 119.6 0.3 1.9e-34 118.9 0.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001279251.1_10724001_1 - 1.8e-30 105.1 13.4 1.8e-30 105.1 13.4 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Piwi PF02171.15 001301752.1_39626001_1 - 2e-87 293.1 0.1 3e-87 292.5 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.20 001301752.1_39626001_1 - 1e-33 116.0 0.4 1.7e-33 115.2 0.4 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.8 001301752.1_39626001_1 - 4.7e-09 35.6 0.0 1.4e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.3 001301752.1_39626001_1 - 0.0036 17.9 0.0 0.0076 16.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute Fer2 PF00111.25 001290587.1_39922001_1 - 8.8e-10 38.3 0.1 1.5e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain adh_short_C2 PF13561.4 001281886.1_39423001_3 - 2.2e-58 197.4 0.0 3.9e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001281886.1_39423001_3 - 1.8e-48 164.5 0.3 2.2e-48 164.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001281886.1_39423001_3 - 9.8e-11 41.7 0.6 1.5e-10 41.2 0.6 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.13 001281886.1_39423001_3 - 0.044 13.6 0.2 0.077 12.7 0.2 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.19 001281886.1_39423001_3 - 0.057 12.7 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AA_permease PF00324.19 001009756.1_39527001_1 - 1.7e-64 218.0 35.9 5.2e-39 134.0 6.5 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.13 001009756.1_39527001_1 - 1.2e-47 162.7 4.0 1e-29 103.7 2.5 3.0 1 1 1 2 2 2 2 Solute carrier family 12 Cys_knot PF00007.20 001280863.1_36322001_3 - 1.7e-32 111.7 15.6 2.7e-32 111.0 15.6 1.3 1 0 0 1 1 1 1 Cystine-knot domain Mito_carr PF00153.25 001195393.1_29622001_1 - 5.8e-67 221.5 3.3 8.1e-25 86.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_8 PF13855.4 001279234.1_39626001_1 - 8.2e-79 259.2 95.9 7.9e-12 44.6 3.3 11.1 7 4 3 11 11 11 11 Leucine rich repeat LRR_4 PF12799.5 001279234.1_39626001_1 - 7.3e-34 115.0 98.5 1.9e-05 24.8 5.9 13.8 6 3 9 16 16 16 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001279234.1_39626001_1 - 2.2e-21 76.0 28.9 1.3e-06 28.3 6.6 6.1 2 1 3 6 6 6 5 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001279234.1_39626001_1 - 8.7e-13 48.0 36.0 5.2e-06 25.9 1.8 7.6 2 1 7 9 9 9 6 Leucine-rich repeat LRR_1 PF00560.31 001279234.1_39626001_1 - 1.5e-10 39.8 85.9 1.5 9.4 0.1 20.7 21 1 0 21 21 21 6 Leucine Rich Repeat LRR_6 PF13516.4 001279234.1_39626001_1 - 3.9e-09 35.7 86.4 0.33 11.0 0.1 18.9 19 0 0 19 19 19 7 Leucine Rich repeat TIR PF01582.18 001279234.1_39626001_1 - 1.1e-08 35.0 0.8 1.9e-08 34.2 0.8 1.4 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.16 001279234.1_39626001_1 - 0.0042 16.6 0.4 0.0042 16.6 0.4 1.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.22 001279234.1_39626001_1 - 0.01 16.2 0.2 0.071 13.6 0.2 2.6 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain TIR_2 PF13676.4 001279234.1_39626001_1 - 0.079 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 TIR domain DUF776 PF05604.9 001284007.1_29523001_2 - 3.9e-93 310.7 15.7 5.4e-93 310.3 15.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF776) Copine PF07002.14 001169012.1_40429001_1 - 1.4e-84 282.8 0.0 2.4e-84 282.0 0.0 1.4 1 0 0 1 1 1 1 Copine RRM_1 PF00076.20 001169012.1_40429001_1 - 6.2e-30 102.7 1.0 1.9e-07 30.7 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C2 PF00168.28 001169012.1_40429001_1 - 3.6e-25 88.1 0.0 2.4e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.7 001169012.1_40429001_1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.26 001169012.1_40429001_1 - 0.0065 16.6 0.1 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain bZIP_1 PF00170.19 001169006.1_40422001_1 - 2.6e-10 40.1 7.6 4.2e-10 39.5 7.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001169006.1_40422001_1 - 1.7e-06 27.8 13.7 2.6e-06 27.3 13.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001169006.1_40422001_1 - 2.1e-05 24.8 6.6 3.6e-05 24.1 6.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.16 001169006.1_40422001_1 - 0.0003 20.8 3.8 0.00069 19.6 3.8 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper HAP1_N PF04849.11 001169006.1_40422001_1 - 0.00086 18.5 2.4 0.0012 18.0 2.4 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Vir_act_alpha_C PF10400.7 001169006.1_40422001_1 - 1.8 9.1 5.3 3.3 8.3 5.3 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term APG6 PF04111.10 001169006.1_40422001_1 - 2.4 7.3 7.0 3.4 6.9 7.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mito_carr PF00153.25 001294327.1_06422001_1 - 3.5e-69 228.6 4.6 2.4e-25 88.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein 7tm_1 PF00001.19 001173415.1_09923001_1 - 2.4e-49 167.9 24.6 4.6e-49 166.9 24.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001173415.1_09923001_1 - 2.8e-11 43.2 22.7 3.5e-11 42.8 22.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001173415.1_09923001_1 - 0.0011 18.2 17.7 0.0017 17.6 17.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF423 PF04241.13 001173415.1_09923001_1 - 0.36 10.9 2.6 0.97 9.5 1.1 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF423) Tissue_fac PF01108.15 001290173.1_44827001_1 - 2.7e-22 78.5 0.2 5.5e-22 77.5 0.2 1.5 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001290173.1_44827001_1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III WRNPLPNID PF15017.4 001290173.1_44827001_1 - 0.31 11.8 4.7 2.5 8.9 0.6 2.7 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Serpin PF00079.18 001174114.2_39523001_1 - 9.5e-107 357.4 0.2 9.5e-107 357.4 0.2 1.3 2 0 0 2 2 2 1 Serpin (serine protease inhibitor) Ephrin PF00812.15 001305198.1_44923001_1 - 8.9e-43 145.5 0.0 2e-42 144.3 0.0 1.5 2 0 0 2 2 2 1 Ephrin Tcp11 PF05794.11 001261173.1_29624001_1 - 1.6e-106 356.9 0.3 2.2e-106 356.4 0.3 1.2 1 0 0 1 1 1 1 T-complex protein 11 Mito_carr PF00153.25 001281305.1_20323001_1 - 3.8e-59 196.5 0.5 5.5e-19 67.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TIR PF01582.18 001279215.1_39625001_1 - 1.4e-27 96.5 0.3 3.2e-27 95.3 0.3 1.7 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001279215.1_39625001_1 - 4.7e-21 74.2 38.0 6.8e-11 41.6 3.4 8.0 3 2 7 10 10 10 8 Leucine rich repeat LRR_4 PF12799.5 001279215.1_39625001_1 - 2.4e-19 68.9 43.3 2e-05 24.7 0.2 9.0 5 1 5 10 10 10 8 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001279215.1_39625001_1 - 3.6e-12 46.4 0.0 9.4e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001279215.1_39625001_1 - 2.9e-07 30.0 6.6 0.061 12.7 0.2 3.5 3 0 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.4 001279215.1_39625001_1 - 2.3e-05 24.0 26.9 3.8 7.7 0.2 10.3 10 0 0 10 10 10 2 Leucine Rich repeat LRRCT PF01463.22 001279215.1_39625001_1 - 4.8e-05 23.5 0.1 0.00016 21.8 0.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001279215.1_39625001_1 - 0.055 13.8 38.4 7.6 7.3 0.1 10.9 10 2 0 10 10 10 0 Leucine Rich Repeat TGF_beta PF00019.18 001169019.1_40423001_1 - 6.5e-14 52.5 0.3 2.9e-13 50.5 0.3 1.9 1 1 0 1 1 1 1 Transforming growth factor beta like domain LRR_8 PF13855.4 001305955.1_10827001_3 - 3.4e-71 234.8 100.9 3.4e-10 39.4 1.9 14.9 11 3 3 14 14 14 14 Leucine rich repeat LRR_4 PF12799.5 001305955.1_10827001_3 - 1.2e-33 114.3 106.7 6.7e-06 26.2 4.5 16.2 6 4 12 20 20 20 16 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001305955.1_10827001_3 - 1.6e-13 50.6 28.1 0.00055 19.8 0.8 7.2 3 1 4 7 7 7 5 Leucine rich repeats (6 copies) TIR PF01582.18 001305955.1_10827001_3 - 6.5e-13 48.7 0.2 1.1e-12 48.0 0.2 1.3 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001305955.1_10827001_3 - 9.7e-12 44.6 44.3 0.006 16.0 1.0 7.5 3 3 3 7 7 7 5 Leucine-rich repeat LRR_1 PF00560.31 001305955.1_10827001_3 - 2e-11 42.5 85.7 0.64 10.6 1.0 21.5 20 6 0 20 20 20 8 Leucine Rich Repeat TIR_2 PF13676.4 001305955.1_10827001_3 - 0.00071 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001305955.1_10827001_3 - 0.0081 16.0 75.0 0.29 11.2 0.4 18.4 21 0 0 21 21 21 4 Leucine Rich repeat FNIP PF05725.10 001305955.1_10827001_3 - 2.4 8.2 24.4 1.4 9.0 0.1 8.4 7 2 0 7 7 7 0 FNIP Repeat IFN-gamma PF00714.15 001290166.1_44822001_2 - 2.1e-69 231.6 7.7 3.1e-69 231.0 7.7 1.2 1 0 0 1 1 1 1 Interferon gamma API5 PF05918.9 001290166.1_44822001_2 - 0.023 13.4 2.2 0.025 13.3 0.5 1.7 1 1 1 2 2 2 0 Apoptosis inhibitory protein 5 (API5) UCH PF00443.27 001285328.1_29525001_1 - 1e-50 172.5 1.8 1e-50 172.5 1.8 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 001285328.1_29525001_1 - 3.1e-14 53.2 9.2 6.6e-14 52.1 9.2 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.4 001285328.1_29525001_1 - 0.017 14.5 2.2 0.024 14.0 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CARD_2 PF16739.3 001290175.1_44828001_3 - 1.2e-45 153.3 0.3 1.3e-21 76.3 0.0 2.7 2 0 0 2 2 2 2 Caspase recruitment domain RIG-I_C-RD PF11648.6 001290175.1_44828001_3 - 9.3e-40 135.4 7.1 1.1e-39 135.3 5.0 2.3 2 0 0 2 2 2 1 C-terminal domain of RIG-I ResIII PF04851.13 001290175.1_44828001_3 - 2.6e-21 76.3 0.3 1.3e-20 73.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.29 001290175.1_44828001_3 - 5.6e-20 71.6 1.0 5.4e-19 68.5 0.3 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.27 001290175.1_44828001_3 - 7.1e-18 64.8 0.0 1.7e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CARD PF00619.19 001290175.1_44828001_3 - 2.4e-14 53.0 0.6 2.7e-10 40.0 1.1 2.6 2 0 0 2 2 2 2 Caspase recruitment domain DUF3638 PF12340.6 001290175.1_44828001_3 - 0.016 14.4 0.0 0.041 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) AAA_22 PF13401.4 001290175.1_44828001_3 - 0.022 14.9 0.4 0.32 11.1 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.4 001290175.1_44828001_3 - 0.048 13.9 1.0 0.19 11.9 0.2 2.5 2 1 0 2 2 2 0 AAA domain PIP5K PF01504.16 001261154.1_29627001_1 - 1.4e-68 231.0 0.0 1.9e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase IL8 PF00048.18 001024589.1_49821001_2 - 2.7e-20 72.1 0.4 4.4e-20 71.4 0.4 1.4 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Dynamin_M PF01031.18 001301762.1_39624001_1 - 1.9e-88 296.3 11.0 1.9e-88 296.3 11.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.21 001301762.1_39624001_1 - 3.2e-50 170.3 2.0 5.2e-50 169.7 0.2 2.3 2 0 0 2 2 2 1 Dynamin family GED PF02212.16 001301762.1_39624001_1 - 5.6e-26 90.4 1.0 5.6e-26 90.4 1.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.21 001301762.1_39624001_1 - 0.0003 20.7 4.2 0.0018 18.2 0.7 3.4 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_21 PF13304.4 001301762.1_39624001_1 - 0.014 15.0 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2120 PF09893.7 001301762.1_39624001_1 - 0.019 15.0 0.4 0.12 12.3 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) AAA_29 PF13555.4 001301762.1_39624001_1 - 0.022 14.4 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.4 001301762.1_39624001_1 - 0.028 14.7 1.1 0.79 9.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.25 001301762.1_39624001_1 - 0.14 12.5 2.9 0.15 12.5 0.0 2.5 2 1 0 2 2 2 0 ABC transporter PP_kinase_N PF13089.4 001301762.1_39624001_1 - 0.84 9.8 5.7 0.75 10.0 1.4 3.1 2 1 1 3 3 3 0 Polyphosphate kinase N-terminal domain TIR PF01582.18 001279183.1_39625001_1 - 1.1e-26 93.6 0.9 1.8e-26 92.9 0.9 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001279183.1_39625001_1 - 6.2e-21 73.8 29.3 7e-11 41.6 4.9 7.3 4 3 4 8 8 8 5 Leucine rich repeat LRR_4 PF12799.5 001279183.1_39625001_1 - 2e-17 62.8 36.4 2e-05 24.7 0.2 8.1 6 2 3 9 9 9 6 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001279183.1_39625001_1 - 9.1e-13 48.3 0.0 1.9e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001279183.1_39625001_1 - 3.2e-07 29.9 7.0 0.0038 16.6 0.6 4.0 3 1 1 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.4 001279183.1_39625001_1 - 4.4e-07 29.3 22.2 0.44 10.6 0.1 10.4 12 0 0 12 12 12 3 Leucine Rich repeat LRRCT PF01463.22 001279183.1_39625001_1 - 4.2e-05 23.6 0.1 0.00017 21.8 0.1 2.2 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001279183.1_39625001_1 - 0.00057 19.9 33.0 2.2 8.9 2.2 11.0 9 3 0 9 9 9 2 Leucine Rich Repeat TIR-like PF10137.7 001279183.1_39625001_1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain UPF0239 PF06783.9 001266836.1_29623001_3 - 1.3e-32 111.7 0.0 1.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) adh_short_C2 PF13561.4 001278540.1_46723001_3 - 1.2e-60 204.9 0.0 1.6e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001278540.1_46723001_3 - 4e-48 163.3 0.1 4.8e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001278540.1_46723001_3 - 6.5e-10 39.1 0.2 9.6e-10 38.5 0.2 1.1 1 0 0 1 1 1 1 KR domain DFP PF04127.13 001278540.1_46723001_3 - 0.004 16.9 0.4 0.0069 16.1 0.4 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.8 001278540.1_46723001_3 - 0.0069 15.7 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Bcl-2 PF00452.17 001280000.1_46722001_2 - 1.2e-34 118.7 0.1 2e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.15 001280000.1_46722001_2 - 1.6e-14 53.2 0.3 2.8e-14 52.4 0.3 1.4 1 0 0 1 1 1 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.4 001280000.1_46722001_2 - 0.022 15.3 0.0 0.032 14.8 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Nitrate_red_del PF02613.13 001280000.1_46722001_2 - 0.13 12.1 0.0 0.53 10.2 0.0 2.0 1 1 1 2 2 2 0 Nitrate reductase delta subunit XRCC4 PF06632.10 001280092.1_35723001_1 - 5.5e-159 528.3 9.6 6.2e-159 528.2 9.6 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF927 PF06048.9 001280092.1_35723001_1 - 0.015 14.7 0.3 0.021 14.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) IncA PF04156.12 001280092.1_35723001_1 - 6.5 6.4 10.3 0.28 10.8 4.2 1.7 2 0 0 2 2 2 0 IncA protein LRR_8 PF13855.4 001109231.1_45726001_2 - 3.8e-08 32.8 15.0 1.5e-05 24.5 5.3 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 001109231.1_45726001_2 - 1.1e-07 31.9 10.1 4.3e-05 23.6 1.3 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001109231.1_45726001_2 - 8.9e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.31 001109231.1_45726001_2 - 0.15 12.5 5.7 11 6.8 0.1 4.3 3 1 1 4 4 4 0 Leucine Rich Repeat DUF4681 PF15732.3 036618.2_45722120_2 - 2.8e-31 108.3 2.4 5.5e-31 107.4 2.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4681) MHC_I PF00129.16 001008849.1_45723001_1 - 1.8e-48 164.4 0.1 2.4e-48 163.9 0.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001008849.1_45723001_1 - 1e-16 61.0 0.0 2.9e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001008849.1_45723001_1 - 1.1e-05 25.8 0.3 0.039 14.4 0.0 2.5 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 001008849.1_45723001_1 - 0.00037 20.4 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001008849.1_45723001_1 - 0.0022 18.0 0.0 0.0056 16.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain MHC_I_3 PF16497.3 001008849.1_45723001_1 - 0.0045 16.4 0.2 0.0068 15.8 0.2 1.3 1 0 0 1 1 1 1 MHC-I family domain DUF4448 PF14610.4 001008849.1_45723001_1 - 0.072 12.7 0.8 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF3377 PF11857.6 001008849.1_45723001_1 - 0.11 12.3 3.8 13 5.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Globin PF00042.20 001329918.1_11722001_2 - 8.8e-32 109.8 0.1 1.3e-30 106.0 0.0 2.0 2 0 0 2 2 2 1 Globin BCA_ABC_TP_C PF12399.6 001329918.1_11722001_2 - 0.08 12.7 0.5 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter WD40 PF00400.30 001280011.1_46723001_1 - 3.2e-63 208.0 17.8 9.9e-09 35.6 0.3 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280011.1_46723001_1 - 1.6e-16 60.2 2.8 0.054 13.7 0.0 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 001280011.1_46723001_1 - 9e-13 47.5 11.7 0.0087 14.6 0.0 6.4 2 2 4 7 7 7 4 Nucleoporin Nup120/160 LisH PF08513.9 001280011.1_46723001_1 - 6.2e-09 35.4 0.4 1.6e-08 34.1 0.4 1.8 1 0 0 1 1 1 1 LisH eIF2A PF08662.9 001280011.1_46723001_1 - 2e-05 24.4 2.1 0.057 13.1 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.9 001280011.1_46723001_1 - 6.8e-05 21.7 2.3 0.43 9.2 0.0 4.2 1 1 4 5 5 5 1 Nup133 N terminal like Ge1_WD40 PF16529.3 001280011.1_46723001_1 - 0.00024 20.0 8.4 0.96 8.2 0.1 4.9 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Pox_A_type_inc PF04508.10 001280011.1_46723001_1 - 0.0015 18.2 0.1 0.0034 17.0 0.1 1.6 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat LisH_2 PF16045.3 001280011.1_46723001_1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 LisH TFIID-31kDa PF02291.13 001286172.1_20323001_3 - 7e-51 171.3 0.0 1e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001286172.1_20323001_3 - 1.2e-07 32.2 0.0 2.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001286172.1_20323001_3 - 2.4e-06 27.7 0.1 4.4e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.11 001286172.1_20323001_3 - 8.6e-05 22.3 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001286172.1_20323001_3 - 0.00017 21.9 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.4 001286172.1_20323001_3 - 0.00024 21.4 0.2 0.00056 20.2 0.2 1.6 1 0 0 1 1 1 1 AAA domain Histone PF00125.22 001286172.1_20323001_3 - 0.00027 21.2 0.3 0.00052 20.3 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 AAA_28 PF13521.4 001286172.1_20323001_3 - 0.00047 20.3 0.0 0.00071 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.4 001286172.1_20323001_3 - 0.0027 17.9 0.1 0.0048 17.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain CENP-T_C PF15511.4 001286172.1_20323001_3 - 0.0029 17.6 0.1 0.0056 16.6 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001286172.1_20323001_3 - 0.0043 17.3 0.1 0.0079 16.4 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.4 001286172.1_20323001_3 - 0.015 15.3 0.5 0.062 13.3 0.5 2.0 1 1 0 1 1 1 0 AAA domain SKI PF01202.20 001286172.1_20323001_3 - 0.018 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.13 001286172.1_20323001_3 - 0.02 14.7 0.2 0.033 14.0 0.2 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.12 001286172.1_20323001_3 - 0.028 14.3 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.4 001286172.1_20323001_3 - 0.053 13.1 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.4 001286172.1_20323001_3 - 0.056 13.6 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.4 001286172.1_20323001_3 - 0.058 12.0 0.1 0.71 8.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.15 001286172.1_20323001_3 - 0.088 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.10 001286172.1_20323001_3 - 0.088 11.9 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ATPase PF06745.11 001286172.1_20323001_3 - 0.12 11.6 0.5 0.31 10.2 0.1 1.8 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.15 001286172.1_20323001_3 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TFIID-31kDa PF02291.13 001286193.1_10723001_2 - 9.3e-51 170.9 0.0 1.3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001286193.1_10723001_2 - 1.9e-07 31.5 0.2 3.8e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001286193.1_10723001_2 - 2.6e-06 27.6 0.1 5.4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein AAA_28 PF13521.4 001286193.1_10723001_2 - 7.9e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.4 001286193.1_10723001_2 - 9.1e-05 22.8 0.1 9.1e-05 22.8 0.1 1.8 2 0 0 2 2 1 1 AAA domain Bromo_TP PF07524.11 001286193.1_10723001_2 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001286193.1_10723001_2 - 0.00025 21.3 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Histone PF00125.22 001286193.1_10723001_2 - 0.0003 21.1 0.3 0.00063 20.0 0.3 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001286193.1_10723001_2 - 0.0039 17.2 0.1 0.0071 16.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001286193.1_10723001_2 - 0.01 16.1 0.5 0.019 15.2 0.5 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.4 001286193.1_10723001_2 - 0.017 15.1 0.4 0.075 13.1 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.4 001286193.1_10723001_2 - 0.02 15.0 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SKI PF01202.20 001286193.1_10723001_2 - 0.024 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.13 001286193.1_10723001_2 - 0.024 14.4 0.2 0.039 13.7 0.2 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.12 001286193.1_10723001_2 - 0.034 14.0 0.1 0.068 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.15 001286193.1_10723001_2 - 0.043 13.7 0.2 0.081 12.8 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ADK PF00406.20 001286193.1_10723001_2 - 0.047 13.7 0.1 0.077 13.0 0.1 1.3 1 0 0 1 1 1 0 Adenylate kinase Cytidylate_kin PF02224.16 001286193.1_10723001_2 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase RuvB_N PF05496.10 001286193.1_10723001_2 - 0.1 11.7 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.4 001286193.1_10723001_2 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.4 001286193.1_10723001_2 - 0.13 10.8 0.2 0.91 8.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain RXT2_N PF08595.9 001286193.1_10723001_2 - 0.15 12.0 1.1 0.24 11.3 1.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal ATPase PF06745.11 001286193.1_10723001_2 - 0.17 11.0 0.5 0.52 9.5 0.1 1.8 2 0 0 2 2 2 0 KaiC CBFD_NFYB_HMF PF00808.21 001286193.1_10723001_2 - 0.4 10.9 0.1 0.4 10.9 0.1 1.8 2 0 0 2 2 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cwf_Cwc_15 PF04889.10 001286193.1_10723001_2 - 0.83 9.2 5.5 1.2 8.7 5.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIID-31kDa PF02291.13 001286202.1_16223001_2 - 5.9e-51 171.5 0.0 8.6e-51 171.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001286202.1_16223001_2 - 9.7e-08 32.5 0.3 2.2e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001286202.1_16223001_2 - 2.4e-06 27.7 0.1 4.7e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.11 001286202.1_16223001_2 - 9e-05 22.3 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001286202.1_16223001_2 - 0.00021 21.6 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.4 001286202.1_16223001_2 - 0.00022 21.5 0.1 0.00046 20.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.4 001286202.1_16223001_2 - 0.00027 21.1 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Histone PF00125.22 001286202.1_16223001_2 - 0.0003 21.0 0.3 0.00055 20.2 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001286202.1_16223001_2 - 0.0034 17.3 0.1 0.0062 16.5 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001286202.1_16223001_2 - 0.0057 16.9 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 001286202.1_16223001_2 - 0.013 15.7 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.4 001286202.1_16223001_2 - 0.013 15.5 0.5 0.052 13.6 0.5 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.13 001286202.1_16223001_2 - 0.017 14.9 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.12 001286202.1_16223001_2 - 0.023 14.6 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SKI PF01202.20 001286202.1_16223001_2 - 0.029 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase TsaE PF02367.15 001286202.1_16223001_2 - 0.055 13.3 0.1 0.094 12.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.10 001286202.1_16223001_2 - 0.059 12.5 0.1 0.094 11.8 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.4 001286202.1_16223001_2 - 0.064 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.4 001286202.1_16223001_2 - 0.087 11.5 0.2 0.8 8.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.4 001286202.1_16223001_2 - 0.12 12.6 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain FBPase PF00316.18 001319798.1_07323001_1 - 2.9e-80 268.1 0.3 3.8e-80 267.7 0.3 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.23 001319798.1_07323001_1 - 6e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Inositol monophosphatase family Ank_5 PF13857.4 001319798.1_07323001_1 - 0.06 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ABC2_membrane PF01061.22 001319798.1_07323001_1 - 0.063 12.6 0.0 0.56 9.5 0.0 2.0 2 0 0 2 2 2 0 ABC-2 type transporter TFIID-31kDa PF02291.13 001286161.1_36523001_1 - 9.7e-51 170.8 0.0 1.4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001286161.1_36523001_1 - 1.9e-07 31.5 0.2 3.9e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001286161.1_36523001_1 - 2.7e-06 27.6 0.1 5.5e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein AAA_17 PF13207.4 001286161.1_36523001_1 - 9.4e-05 22.7 0.1 9.4e-05 22.7 0.1 1.7 2 0 0 2 2 1 1 AAA domain Bromo_TP PF07524.11 001286161.1_36523001_1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA_28 PF13521.4 001286161.1_36523001_1 - 0.00012 22.3 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.27 001286161.1_36523001_1 - 0.00024 21.4 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Histone PF00125.22 001286161.1_36523001_1 - 0.00031 21.0 0.3 0.00065 20.0 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001286161.1_36523001_1 - 0.0041 17.1 0.1 0.0073 16.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001286161.1_36523001_1 - 0.01 16.1 0.2 0.019 15.2 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.10 001286161.1_36523001_1 - 0.021 14.0 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.4 001286161.1_36523001_1 - 0.021 14.8 0.5 0.083 12.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain SKI PF01202.20 001286161.1_36523001_1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.13 001286161.1_36523001_1 - 0.025 14.4 0.2 0.04 13.7 0.2 1.3 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.4 001286161.1_36523001_1 - 0.025 14.7 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.12 001286161.1_36523001_1 - 0.041 13.8 0.6 0.069 13.0 0.1 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) ADK PF00406.20 001286161.1_36523001_1 - 0.056 13.4 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Adenylate kinase Cytidylate_kin PF02224.16 001286161.1_36523001_1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.4 001286161.1_36523001_1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.15 001286161.1_36523001_1 - 0.11 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_32 PF13654.4 001286161.1_36523001_1 - 0.14 10.8 0.2 0.93 8.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.11 001286161.1_36523001_1 - 0.14 11.3 0.3 0.68 9.1 0.0 1.9 2 0 0 2 2 2 0 KaiC RXT2_N PF08595.9 001286161.1_36523001_1 - 0.19 11.6 1.9 0.3 10.9 1.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.10 001286161.1_36523001_1 - 0.87 9.1 6.3 1.3 8.6 6.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Connexin PF00029.17 001172761.1_09923001_1 - 1.7e-83 279.7 7.3 2.4e-83 279.2 7.3 1.2 1 0 0 1 1 1 1 Connexin BPD_transp_2 PF02653.14 001172761.1_09923001_3 - 3.7e-13 49.1 7.6 4.8e-13 48.7 7.6 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Synuclein PF01387.15 001287378.1_52121001_1 - 1.7e-51 173.8 17.0 1.9e-51 173.6 17.0 1.0 1 0 0 1 1 1 1 Synuclein TFIID-31kDa PF02291.13 001286187.1_48823001_1 - 7.5e-51 171.2 0.0 1.1e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001286187.1_48823001_1 - 1.1e-07 32.3 0.2 2.3e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001286187.1_48823001_1 - 2.3e-06 27.7 0.1 4.6e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein AAA_28 PF13521.4 001286187.1_48823001_1 - 5.4e-05 23.4 0.0 8.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.4 001286187.1_48823001_1 - 8.8e-05 22.8 0.1 8.8e-05 22.8 0.1 1.8 2 0 0 2 2 1 1 AAA domain Bromo_TP PF07524.11 001286187.1_48823001_1 - 8.8e-05 22.3 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001286187.1_48823001_1 - 0.00022 21.5 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Histone PF00125.22 001286187.1_48823001_1 - 0.00025 21.3 0.3 0.00054 20.2 0.3 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001286187.1_48823001_1 - 0.0033 17.4 0.1 0.0061 16.5 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001286187.1_48823001_1 - 0.007 16.6 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.4 001286187.1_48823001_1 - 0.014 15.5 0.6 0.057 13.4 0.6 2.1 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.13 001286187.1_48823001_1 - 0.017 14.9 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.10 001286187.1_48823001_1 - 0.018 14.2 0.1 0.03 13.5 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.4 001286187.1_48823001_1 - 0.02 15.0 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.12 001286187.1_48823001_1 - 0.028 14.3 0.7 0.049 13.5 0.1 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) SKI PF01202.20 001286187.1_48823001_1 - 0.029 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase TsaE PF02367.15 001286187.1_48823001_1 - 0.08 12.8 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.4 001286187.1_48823001_1 - 0.093 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain ADK PF00406.20 001286187.1_48823001_1 - 0.096 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Adenylate kinase AAA_32 PF13654.4 001286187.1_48823001_1 - 0.096 11.3 0.2 0.78 8.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.11 001286187.1_48823001_1 - 0.15 11.3 0.3 0.55 9.4 0.0 1.9 2 0 0 2 2 2 0 KaiC RXT2_N PF08595.9 001286187.1_48823001_1 - 0.29 11.0 2.7 0.48 10.3 2.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.10 001286187.1_48823001_1 - 1.3 8.6 7.1 1.9 8.1 7.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIID-31kDa PF02291.13 001286165.1_37423001_1 - 9.8e-51 170.8 0.0 1.4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001286165.1_37423001_1 - 1.4e-07 32.0 0.2 2.8e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001286165.1_37423001_1 - 2.9e-06 27.4 0.1 5.5e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein AAA_28 PF13521.4 001286165.1_37423001_1 - 6.7e-05 23.1 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.4 001286165.1_37423001_1 - 0.0001 22.6 0.1 0.0001 22.6 0.1 1.8 2 0 0 2 2 1 1 AAA domain Bromo_TP PF07524.11 001286165.1_37423001_1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001286165.1_37423001_1 - 0.00027 21.2 0.0 0.00045 20.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Histone PF00125.22 001286165.1_37423001_1 - 0.00035 20.9 0.3 0.00065 20.0 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001286165.1_37423001_1 - 0.0041 17.1 0.1 0.0074 16.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001286165.1_37423001_1 - 0.0065 16.7 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.10 001286165.1_37423001_1 - 0.011 14.9 0.1 0.019 14.1 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.4 001286165.1_37423001_1 - 0.017 15.1 0.6 0.067 13.2 0.6 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.13 001286165.1_37423001_1 - 0.02 14.7 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.12 001286165.1_37423001_1 - 0.024 14.5 0.1 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.4 001286165.1_37423001_1 - 0.026 14.6 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain SKI PF01202.20 001286165.1_37423001_1 - 0.035 14.1 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase TsaE PF02367.15 001286165.1_37423001_1 - 0.044 13.7 0.1 0.078 12.8 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.4 001286165.1_37423001_1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain ADK PF00406.20 001286165.1_37423001_1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase AAA_32 PF13654.4 001286165.1_37423001_1 - 0.13 10.9 0.2 0.94 8.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.11 001286165.1_37423001_1 - 0.2 10.8 0.3 0.64 9.2 0.0 1.8 2 0 0 2 2 2 0 KaiC Cwf_Cwc_15 PF04889.10 001286165.1_37423001_1 - 1.5 8.3 6.6 2.2 7.8 6.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Stk19 PF10494.7 001329950.1_11722001_1 - 4.9e-39 134.4 0.0 7.2e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 LBP_BPI_CETP PF01273.23 001282365.1_11322001_1 - 4.3e-39 133.6 2.1 5.3e-39 133.3 2.1 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Abi_HHR PF07815.12 001131345.1_43524001_1 - 4.2e-28 97.2 0.0 7.1e-28 96.4 0.0 1.3 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.4 001131345.1_43524001_1 - 4.5e-13 48.7 0.3 1.4e-12 47.1 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.26 001131345.1_43524001_1 - 3.1e-10 39.3 0.0 4.9e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001131345.1_43524001_1 - 9.6e-09 34.7 0.1 1.8e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PMG PF05287.10 001329969.1_11722001_1 - 3.4e-44 150.9 58.8 3.9e-44 150.7 58.8 1.0 1 0 0 1 1 1 1 PMG protein Keratin_B2 PF01500.15 001329969.1_11722001_1 - 0.14 12.0 48.2 0.0095 15.8 35.1 2.1 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein PMG PF05287.10 001329967.1_11721001_1 - 4.1e-15 56.2 9.6 5.4e-15 55.8 9.6 1.2 1 0 0 1 1 1 1 PMG protein PMG PF05287.10 001329967.1_11721001_3 - 9.6e-12 45.2 10.3 1.2e-11 44.8 10.3 1.1 1 0 0 1 1 1 1 PMG protein Keratin_B2_2 PF13885.4 001329967.1_11721001_3 - 2.2 8.2 18.9 5.9 6.8 18.9 1.7 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Ferlin_C PF16165.3 001318039.1_11729001_2 - 6e-70 234.0 0.2 6e-70 234.0 0.2 1.6 2 0 0 2 2 2 1 Ferlin C-terminus C2 PF00168.28 001318039.1_11729001_2 - 7.6e-61 202.7 0.0 3.5e-17 62.5 0.0 7.8 8 0 0 8 8 8 7 C2 domain FerB PF08150.10 001318039.1_11729001_2 - 2.6e-24 85.5 0.0 7.4e-24 84.0 0.0 1.8 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.10 001318039.1_11729001_2 - 4.5e-16 58.5 0.0 1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 FerI (NUC094) domain DUF2628 PF10947.6 001318039.1_11729001_2 - 0.045 14.0 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Ribosomal_L36 PF00444.16 001329980.1_39722001_3 - 2e-14 53.4 8.2 3.8e-14 52.5 8.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 Ferlin_C PF16165.3 001318032.1_29729001_3 - 2.1e-68 229.0 0.2 3.8e-68 228.1 0.2 1.5 1 0 0 1 1 1 1 Ferlin C-terminus C2 PF00168.28 001318032.1_29729001_3 - 2.3e-62 207.6 0.0 3e-17 62.7 0.0 8.1 8 0 0 8 8 8 7 C2 domain FerB PF08150.10 001318032.1_29729001_3 - 1.1e-23 83.5 0.0 3.9e-23 81.7 0.0 2.0 2 0 0 2 2 2 1 FerB (NUC096) domain FerI PF08151.10 001318032.1_29729001_3 - 3.8e-16 58.8 0.0 8.7e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain DUF2628 PF10947.6 001318032.1_29729001_3 - 0.034 14.3 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Aminotran_5 PF00266.17 001169013.1_40423001_1 - 3.2e-91 305.9 0.0 3.6e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.19 001169013.1_40423001_1 - 2.6e-10 39.9 0.0 3.8e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.15 001169013.1_40423001_1 - 3.4e-05 23.2 0.1 5.2e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.17 001169013.1_40423001_1 - 0.0053 15.4 0.0 0.01 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain P53 PF00870.16 001319288.1_34023001_1 - 3.2e-115 382.5 0.8 4.5e-115 382.0 0.8 1.2 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.9 001319288.1_34023001_1 - 2.2e-17 62.0 2.6 4.3e-17 61.0 2.6 1.5 1 0 0 1 1 1 1 P53 tetramerisation motif P53_TAD PF08563.9 001319288.1_34023001_1 - 5.5e-13 47.9 4.3 1.6e-12 46.4 4.3 1.9 1 0 0 1 1 1 1 P53 transactivation motif TLV_coat PF00429.17 001305383.1_34024001_1 - 3.5e-61 207.4 12.6 6e-57 193.4 0.9 3.0 2 1 0 3 3 3 3 ENV polyprotein (coat polyprotein) Trypsin PF00089.24 001329959.1_11726001_3 - 2e-48 165.0 0.0 3.3e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin VWA PF00092.26 001329959.1_11726001_3 - 1.1e-38 133.1 0.0 1.7e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sushi PF00084.18 001329959.1_11726001_3 - 1.4e-24 86.3 23.3 7.1e-12 45.6 2.3 4.3 5 0 0 5 5 5 3 Sushi repeat (SCR repeat) VWA_2 PF13519.4 001329959.1_11726001_3 - 8.7e-11 42.3 0.0 3.1e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain HRM PF02793.20 001329959.1_11726001_3 - 0.00052 20.1 10.1 1.3 9.2 0.4 3.5 2 1 1 3 3 3 3 Hormone receptor domain DUF1986 PF09342.9 001329959.1_11726001_3 - 0.0073 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001329959.1_11726001_3 - 0.014 16.2 0.0 0.053 14.3 0.0 2.0 1 1 0 1 1 1 0 Trypsin-like peptidase domain DUF316 PF03761.13 001329959.1_11726001_3 - 0.12 11.8 0.0 2.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 EpoR_lig-bind PF09067.8 001301677.1_34024001_1 - 1.2e-25 89.6 0.0 1.8e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.19 001301677.1_34024001_1 - 2.3e-08 34.1 0.0 4.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Glyco_hydro_79n PF03662.12 001301679.1_34025001_3 - 2.5e-25 89.0 0.0 1e-24 87.0 0.1 1.8 1 1 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain Ank_2 PF12796.5 001330099.1_34022001_2 - 1.6e-32 111.8 5.1 1.4e-17 63.9 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001330099.1_34022001_2 - 9.2e-20 70.6 1.4 5.9e-14 52.1 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001330099.1_34022001_2 - 1.9e-18 64.5 1.9 4.1e-05 23.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.28 001330099.1_34022001_2 - 5.1e-18 64.5 4.4 1.7e-05 24.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.4 001330099.1_34022001_2 - 2e-17 62.9 7.4 1.4e-07 31.6 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Aldo_ket_red PF00248.19 001319875.1_08522001_1 - 3e-56 190.6 0.0 4e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.4 001290909.1_07325001_1 - 1.1e-49 164.6 93.1 9e-09 35.3 0.7 11.3 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.24 001290909.1_07325001_1 - 2.7e-33 112.4 102.0 8e-05 22.7 1.1 11.2 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001290909.1_07325001_1 - 8.2e-26 88.3 96.5 0.0048 17.5 2.7 11.3 11 0 0 11 11 11 10 C2H2-type zinc finger zf-H2C2_5 PF13909.4 001290909.1_07325001_1 - 1e-14 53.8 87.9 9.7e-07 28.3 0.6 10.5 11 0 0 11 11 11 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.6 001290909.1_07325001_1 - 1.3e-08 34.8 57.2 0.022 15.0 0.2 10.9 9 1 2 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001290909.1_07325001_1 - 0.0068 16.6 2.5 0.0068 16.6 2.5 10.3 12 0 0 12 12 11 5 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.3 001290909.1_07325001_1 - 0.77 10.4 41.8 0.82 10.3 0.6 5.9 2 1 4 7 7 7 0 zinc-ribbon family zf-C2H2_2 PF12756.5 001290909.1_07325001_1 - 1.1 9.5 60.2 2.2 8.5 6.8 7.5 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-ribbon_3 PF13248.4 001290909.1_07325001_1 - 1.2 8.6 10.7 4.4 6.7 0.1 5.1 5 0 0 5 5 5 0 zinc-ribbon domain GAGA PF09237.9 001290909.1_07325001_1 - 2.7 7.7 30.5 3 7.6 0.0 7.7 2 2 8 10 10 10 0 GAGA factor Actin_micro PF17003.3 001290909.1_07325001_1 - 9.3 5.2 44.9 5.7 5.9 2.9 6.9 1 1 5 6 6 6 0 Putative actin-like family Cys_knot PF00007.20 001290881.1_07321001_1 - 1.9e-34 118.0 14.4 2.4e-34 117.7 14.4 1.1 1 0 0 1 1 1 1 Cystine-knot domain Autophagy_C PF10381.7 001290881.1_07321001_2 - 1.2 8.6 4.4 1.3 8.5 1.6 2.1 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal Trypsin PF00089.24 001305930.1_29723001_3 - 6.3e-66 222.2 0.1 7.3e-66 222.0 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001305930.1_29723001_3 - 1.1e-06 29.4 0.0 1.6e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001305930.1_29723001_3 - 2.4e-06 27.8 0.0 4.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) FPN1 PF06963.10 001132161.1_43527001_1 - 1.5e-191 636.6 14.2 1.8e-191 636.3 14.2 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF347 PF03988.10 001132161.1_43527001_1 - 9.5 6.4 9.9 0.57 10.3 0.1 3.6 3 1 0 3 3 3 0 Repeat of Unknown Function (DUF347) TIR PF01582.18 001320281.1_44826001_2 - 1.1e-26 93.5 2.0 2.1e-26 92.6 2.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001320281.1_44826001_2 - 1.2e-22 79.3 31.0 2.6e-11 43.0 5.6 7.0 4 2 4 8 8 8 6 Leucine rich repeat LRR_4 PF12799.5 001320281.1_44826001_2 - 8.7e-17 60.8 30.3 8.2e-07 29.1 1.3 8.0 4 2 3 8 8 8 5 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001320281.1_44826001_2 - 9.6e-12 45.0 0.0 1.7e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001320281.1_44826001_2 - 1.7e-09 37.3 4.5 0.0024 17.3 0.0 3.5 3 0 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.4 001320281.1_44826001_2 - 1.5e-07 30.7 22.6 0.43 10.6 0.1 10.0 11 0 0 11 11 11 3 Leucine Rich repeat LRRCT PF01463.22 001320281.1_44826001_2 - 0.12 12.8 0.5 0.48 11.0 0.1 2.3 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain LRRNT PF01462.16 001320281.1_44826001_2 - 0.15 11.6 0.7 0.63 9.6 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.31 001320281.1_44826001_2 - 1.5 9.4 51.2 2.1 9.0 0.2 11.5 12 2 1 13 13 13 0 Leucine Rich Repeat MACPF PF01823.17 001305924.1_29725001_1 - 1.5e-38 132.9 0.0 1.9e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 MAC/Perforin domain C2 PF00168.28 001305924.1_29725001_1 - 9.6e-10 38.5 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain PX PF00787.22 001280645.1_52223001_1 - 1.3e-19 70.1 0.0 2.1e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.22 001280645.1_52223001_1 - 2.3e-15 56.1 0.2 5.8e-15 54.8 0.2 1.7 2 0 0 2 2 2 1 PB1 domain SH3_1 PF00018.26 001280645.1_52223001_1 - 1.3e-12 47.0 0.1 8.5e-12 44.4 0.0 2.5 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.15 001280645.1_52223001_1 - 3.2e-12 45.8 0.0 5.7e-11 41.8 0.0 2.8 3 0 0 3 3 3 1 Variant SH3 domain SH3_9 PF14604.4 001280645.1_52223001_1 - 8.8e-12 44.6 0.4 4.3e-11 42.3 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain Integrin_alpha2 PF08441.10 001303547.1_08527001_3 - 1.1e-113 380.5 0.0 1.3e-113 380.3 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 001303547.1_08527001_3 - 2.1e-21 75.6 18.5 2.2e-09 37.1 0.0 5.2 5 0 0 5 5 5 3 FG-GAP repeat VCBS PF13517.4 001303547.1_08527001_3 - 5.8e-12 45.9 7.2 9.7e-06 26.0 0.8 4.4 4 1 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001303547.1_08527001_3 - 1.6e-05 24.4 0.3 4.2e-05 23.1 0.3 1.8 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region DUF4365 PF14280.4 001303547.1_08527001_3 - 0.022 14.6 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) STAT_bind PF02864.13 001314278.1_09025001_1 - 5.6e-76 255.6 0.0 5.6e-76 255.6 0.0 2.0 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.18 001314278.1_09025001_1 - 4.5e-56 189.4 18.1 8.9e-56 188.4 18.1 1.5 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.15 001314278.1_09025001_1 - 8.3e-38 129.5 7.9 8.3e-38 129.5 7.9 3.4 3 1 1 4 4 3 1 STAT protein, protein interaction domain SH2 PF00017.22 001314278.1_09025001_1 - 1.4e-13 50.5 0.0 3.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain E2R135 PF11570.6 001314278.1_09025001_1 - 0.1 12.8 1.1 0.2 11.8 1.1 1.4 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 YojJ PF10372.7 001314278.1_09025001_1 - 0.23 11.5 7.1 1.1 9.3 0.4 2.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Syntaxin-6_N PF09177.9 001314278.1_09025001_1 - 0.49 10.9 7.6 0.43 11.0 2.4 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.8 001314278.1_09025001_1 - 1.2 9.2 12.7 0.91 9.6 7.4 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RecG_N PF17190.2 001314278.1_09025001_1 - 1.3 9.7 10.1 1.9 9.2 0.2 3.8 3 1 0 3 3 3 0 RecG N-terminal helical domain Baculo_PEP_C PF04513.10 001314278.1_09025001_1 - 1.3 8.9 5.3 1.3 8.9 3.4 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MerR-DNA-bind PF09278.9 001314278.1_09025001_1 - 3.5 8.1 14.8 3.1 8.3 0.6 3.9 4 0 0 4 4 4 0 MerR, DNA binding DUF1664 PF07889.10 001314278.1_09025001_1 - 3.8 7.4 9.3 6.1 6.7 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF2408 PF10303.7 001314278.1_09025001_1 - 4.1 7.8 7.7 4.1 7.8 1.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF342 PF03961.11 001314278.1_09025001_1 - 7.1 5.0 8.7 0.45 8.9 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Tropomyosin_1 PF12718.5 001314278.1_09025001_1 - 7.7 6.5 11.6 1 9.4 6.3 2.0 2 0 0 2 2 2 0 Tropomyosin like CSD PF00313.20 001290843.1_07322001_1 - 8.4e-17 60.7 0.3 2.4e-16 59.2 0.3 1.7 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.21 001290843.1_07322001_1 - 1.7e-08 34.0 9.4 4.2e-05 23.3 3.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.4 001290843.1_07322001_1 - 0.015 14.9 9.3 0.39 10.3 1.6 2.5 2 0 0 2 2 2 0 Zinc knuckle S1 PF00575.21 001290843.1_07322001_1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain CusF_Ec PF11604.6 001290843.1_07322001_1 - 0.17 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF zf-CCHC_6 PF15288.4 001290843.1_07322001_1 - 0.2 11.4 8.0 1.7 8.4 1.1 2.5 2 0 0 2 2 2 0 Zinc knuckle IL8 PF00048.18 001292081.1_11721001_2 - 3.8e-16 58.9 0.8 7e-16 58.0 0.6 1.5 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.18 001310189.1_33421001_1 - 5.1e-21 74.4 0.8 6.9e-21 74.0 0.8 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.18 001305905.1_29721001_1 - 1.1e-23 83.0 3.0 1.3e-23 82.7 3.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF4725 PF15854.3 001305905.1_29721001_1 - 0.029 14.5 0.3 0.036 14.2 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4725) STAT_bind PF02864.13 001323591.1_46428001_1 - 2.2e-78 263.4 0.2 2.2e-78 263.4 0.2 1.9 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.18 001323591.1_46428001_1 - 6.5e-54 182.4 20.4 6.5e-54 182.4 20.4 1.9 2 0 0 2 2 2 1 STAT protein, all-alpha domain STAT_int PF02865.15 001323591.1_46428001_1 - 8.9e-40 135.8 8.5 8.9e-40 135.8 8.5 3.0 3 0 0 3 3 3 1 STAT protein, protein interaction domain STAT1_TAZ2bind PF12162.6 001323591.1_46428001_1 - 1.5e-13 49.9 0.2 3e-13 48.9 0.2 1.5 1 0 0 1 1 1 1 STAT1 TAZ2 binding domain SH2 PF00017.22 001323591.1_46428001_1 - 4.7e-09 36.0 0.1 2.8e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 SH2 domain TRPM_tetra PF16519.3 001323591.1_46428001_1 - 0.29 11.1 8.0 0.63 10.1 0.4 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF4407 PF14362.4 001323591.1_46428001_1 - 3.3 6.9 6.2 5.3 6.2 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCLC PF05934.9 001329797.1_11725001_1 - 0 1159.9 0.0 0 1159.7 0.0 1.0 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) MCLC PF05934.9 001329797.1_11725001_3 - 3e-66 224.2 1.2 3.8e-66 223.8 1.2 1.1 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) 7tm_1 PF00001.19 001317071.1_52123001_1 - 7.5e-55 185.9 13.3 2.1e-54 184.5 13.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001317071.1_52123001_1 - 0.0007 18.9 10.3 0.0011 18.3 10.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cyclin_N PF00134.21 001317071.1_52123001_1 - 0.044 13.4 0.1 0.074 12.7 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain TrbC PF04956.11 001317071.1_52123001_1 - 0.46 10.6 8.0 1.8 8.7 0.2 2.7 3 0 0 3 3 3 0 TrbC/VIRB2 family DUF2701 PF10857.6 001317071.1_52123001_1 - 2.2 8.2 6.1 1.6 8.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) IL8 PF00048.18 001310170.1_33423001_1 - 1.8e-12 47.0 1.8 4.2e-12 45.9 1.2 1.9 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like RRM_1 PF00076.20 001286596.1_40025001_3 - 1.4e-07 31.1 0.0 2.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tox-ODYAM1 PF15642.4 001286596.1_40025001_3 - 0.24 10.2 1.5 0.39 9.5 1.5 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Integrin_alpha2 PF08441.10 001303572.1_08527001_1 - 4.8e-123 411.4 0.0 5.7e-123 411.1 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 001303572.1_08527001_1 - 8.7e-28 96.0 28.9 6.1e-08 32.5 3.8 4.8 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.4 001303572.1_08527001_1 - 2e-15 57.0 10.3 3.7e-05 24.1 0.1 4.7 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001303572.1_08527001_1 - 7.5e-05 22.3 0.7 0.00017 21.2 0.7 1.7 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.3 001303572.1_08527001_1 - 0.00038 20.0 0.0 0.00057 19.4 0.0 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family IL8 PF00048.18 001310176.1_33422001_2 - 8.1e-16 57.8 0.9 1.8e-15 56.7 0.9 1.6 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like TRH PF05438.10 001310176.1_33422001_2 - 0.064 12.9 6.5 0.094 12.3 6.5 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) 7tm_3 PF00003.20 001314264.1_09023001_2 - 6.4e-23 81.6 32.0 1e-22 81.0 31.4 1.5 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF1345 PF07077.9 001314264.1_09023001_2 - 2.4 7.7 14.7 0.038 13.5 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF373 PF04123.11 001314264.1_09023001_2 - 4.5 6.5 11.3 8.8 5.5 11.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Ldl_recept_a PF00057.16 001199891.1_49826001_1 - 1.2e-73 242.9 139.9 3.2e-12 46.3 10.2 8.1 8 0 0 8 8 7 7 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.15 001199891.1_49826001_1 - 1.1e-57 192.2 2.9 1.1e-13 51.3 0.0 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.4 001199891.1_49826001_1 - 1.3e-14 54.0 34.8 3e-09 36.9 7.8 6.2 6 1 0 6 6 4 3 Coagulation Factor Xa inhibitory site cEGF PF12662.5 001199891.1_49826001_1 - 2.5e-07 30.4 7.7 7.8e-07 28.8 1.4 5.1 4 0 0 4 4 3 2 Complement Clr-like EGF-like SGL PF08450.10 001199891.1_49826001_1 - 3.6e-07 29.9 0.1 0.0088 15.5 0.0 2.7 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region EGF_CA PF07645.13 001199891.1_49826001_1 - 5.3e-06 26.4 8.6 5.3e-06 26.4 8.6 9.3 5 2 4 10 10 5 2 Calcium-binding EGF domain TMEM154 PF15102.4 001199891.1_49826001_1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.7 1 1 0 1 1 1 1 TMEM154 protein family EGF_3 PF12947.5 001199891.1_49826001_1 - 0.016 15.3 2.5 0.016 15.3 2.5 7.8 7 1 1 8 8 3 0 EGF domain SKG6 PF08693.8 001199891.1_49826001_1 - 0.037 13.3 0.8 0.081 12.2 0.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4690 PF15756.3 001199891.1_49826001_1 - 0.044 14.2 3.9 0.16 12.5 2.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4690) Arylesterase PF01731.18 001199891.1_49826001_1 - 0.092 12.8 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Arylesterase PAP_PilO PF06864.10 001199891.1_49826001_1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) AF-4 PF05110.11 001199891.1_49826001_1 - 2.4 6.0 6.2 3.4 5.5 6.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Dynamin_M PF01031.18 001305954.1_10824001_1 - 9.6e-87 290.7 10.4 2.4e-86 289.4 10.4 1.7 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.21 001305954.1_10824001_1 - 2.4e-49 167.5 0.1 2.4e-49 167.5 0.1 2.6 2 1 0 2 2 2 1 Dynamin family GED PF02212.16 001305954.1_10824001_1 - 1.7e-26 92.0 1.6 1.7e-26 92.0 1.6 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.21 001305954.1_10824001_1 - 0.00015 21.7 2.8 0.0021 18.0 0.4 3.5 3 2 0 3 3 3 1 50S ribosome-binding GTPase AAA_21 PF13304.4 001305954.1_10824001_1 - 0.011 15.5 0.0 0.038 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.4 001305954.1_10824001_1 - 0.021 14.4 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.4 001305954.1_10824001_1 - 0.025 14.8 1.2 0.77 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.25 001305954.1_10824001_1 - 0.037 14.4 2.2 0.078 13.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter DUF2120 PF09893.7 001305954.1_10824001_1 - 0.048 13.6 0.2 0.048 13.6 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF4886 PF16227.3 001305954.1_10824001_1 - 0.054 12.5 1.7 0.11 11.5 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) AA_permease_2 PF13520.4 001318341.1_52724001_1 - 1.1e-58 199.0 39.8 1.3e-58 198.7 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.19 001318341.1_52724001_1 - 3.8e-32 111.4 38.4 6.8e-32 110.5 38.4 1.3 1 1 0 1 1 1 1 Amino acid permease FBPase PF00316.18 001290866.1_07323001_1 - 6.9e-75 250.6 0.3 9.2e-75 250.2 0.3 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.23 001290866.1_07323001_1 - 2.8e-05 23.6 0.0 5.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family 7tm_1 PF00001.19 001172875.1_09923001_1 - 1.6e-52 178.3 21.5 3.4e-52 177.2 21.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.19 001135970.1_22423001_1 - 3.9e-51 173.7 25.4 9.9e-51 172.4 25.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001135970.1_22423001_1 - 4.5e-08 32.7 21.1 5.6e-08 32.4 21.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Sugar_tr PF00083.22 001305197.1_44924001_1 - 7.5e-152 506.2 18.2 8.6e-152 506.0 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001305197.1_44924001_1 - 1.6e-17 63.3 41.9 1.4e-16 60.3 34.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.3 001305197.1_44924001_1 - 0.01 15.4 0.2 0.056 13.1 0.2 2.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 HD PF01966.20 001292080.1_11724001_1 - 5.4e-18 65.2 0.0 1.7e-17 63.6 0.0 1.8 2 0 0 2 2 2 1 HD domain SAM_2 PF07647.15 001292080.1_11724001_1 - 1.7e-09 37.5 0.0 3.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001292080.1_11724001_1 - 3.2e-09 37.0 0.0 7.7e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001292080.1_11724001_1 - 0.0083 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase AAA_18 PF13238.4 001286190.1_10722001_2 - 2.4e-30 105.6 0.0 4e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.4 001286190.1_10722001_2 - 4e-07 30.4 0.1 1e-06 29.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.4 001286190.1_10722001_2 - 5.7e-05 23.3 0.0 8.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.27 001286190.1_10722001_2 - 5.9e-05 23.4 0.0 0.00019 21.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.20 001286190.1_10722001_2 - 0.00062 19.8 1.5 0.02 14.9 0.0 2.5 2 1 1 3 3 3 1 Shikimate kinase AAA_33 PF13671.4 001286190.1_10722001_2 - 0.0011 19.0 0.1 0.033 14.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.4 001286190.1_10722001_2 - 0.0012 19.1 0.4 0.0029 17.9 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain ADK PF00406.20 001286190.1_10722001_2 - 0.0027 17.7 0.0 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_22 PF13401.4 001286190.1_10722001_2 - 0.0041 17.2 2.2 0.017 15.3 0.3 2.2 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.13 001286190.1_10722001_2 - 0.0083 15.9 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.12 001286190.1_10722001_2 - 0.011 15.5 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.16 001286190.1_10722001_2 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase TsaE PF02367.15 001286190.1_10722001_2 - 0.02 14.7 0.2 0.035 14.0 0.2 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.17 001286190.1_10722001_2 - 0.03 14.0 2.5 3.5 7.3 0.3 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.20 001286190.1_10722001_2 - 0.037 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.4 001286190.1_10722001_2 - 0.038 13.6 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.10 001286190.1_10722001_2 - 0.041 13.0 0.1 0.064 12.4 0.1 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KTI12 PF08433.8 001286190.1_10722001_2 - 0.049 12.9 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_14 PF13173.4 001286190.1_10722001_2 - 0.076 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.11 001286190.1_10722001_2 - 0.091 12.0 0.7 0.24 10.6 0.1 1.8 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.9 001286190.1_10722001_2 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.15 001286190.1_10722001_2 - 0.15 11.6 0.6 1.6 8.3 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase Homeobox PF00046.27 001289867.1_52224001_2 - 1.9e-20 72.3 7.9 3.6e-20 71.4 7.9 1.5 1 0 0 1 1 1 1 Homeobox domain Integrin_beta PF00362.16 001318340.1_52726001_3 - 4.6e-116 386.7 0.0 6.7e-116 386.1 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.9 001318340.1_52726001_3 - 6e-17 60.9 0.8 6e-17 60.9 0.8 1.7 2 0 0 2 2 2 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.10 001318340.1_52726001_3 - 3.6e-16 59.3 1.5 3.6e-16 59.3 1.5 3.9 4 1 0 4 4 4 1 Integrin beta tail domain PSI_integrin PF17205.1 001318340.1_52726001_3 - 3.9e-14 52.1 7.5 3.9e-14 52.1 7.5 4.2 4 0 0 4 4 4 1 Integrin plexin domain EGF_2 PF07974.11 001318340.1_52726001_3 - 0.00029 21.0 29.6 0.0011 19.2 11.9 7.3 7 3 2 9 9 9 4 EGF-like domain Integrin_beta PF00362.16 001290912.1_07325001_1 - 3.8e-115 383.7 0.0 5.5e-115 383.1 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.9 001290912.1_07325001_1 - 4.4e-16 58.1 0.6 7.5e-16 57.4 0.6 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.10 001290912.1_07325001_1 - 5.5e-15 55.5 2.0 5.5e-15 55.5 2.0 4.1 3 1 1 4 4 4 1 Integrin beta tail domain PSI_integrin PF17205.1 001290912.1_07325001_1 - 7.1e-15 54.4 7.7 7.1e-15 54.4 7.7 4.8 5 0 0 5 5 5 1 Integrin plexin domain EGF_2 PF07974.11 001290912.1_07325001_1 - 3e-11 43.4 82.4 0.0002 21.5 11.5 6.5 4 2 1 5 5 5 4 EGF-like domain IL8 PF00048.18 001305906.1_29721001_1 - 8.7e-26 89.7 2.9 1.3e-25 89.2 2.9 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like adh_short_C2 PF13561.4 001278660.1_33423001_1 - 7.3e-59 199.0 0.0 9.5e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001278660.1_33423001_1 - 3.8e-50 169.9 0.2 5e-50 169.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001278660.1_33423001_1 - 2.2e-10 40.6 0.2 3.2e-10 40.1 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.8 001278660.1_33423001_1 - 0.0019 17.5 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) YjeF_N PF03853.13 001278660.1_33423001_1 - 0.019 14.7 0.2 0.036 13.8 0.2 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus F420_oxidored PF03807.15 001278660.1_33423001_1 - 0.057 13.9 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.19 001278660.1_33423001_1 - 0.18 11.1 0.4 0.44 9.8 0.4 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family V-set PF07686.15 001305952.1_10823001_1 - 1.4e-07 31.5 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set_2 PF15910.3 001305952.1_10823001_1 - 8e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 ICOS V-set domain Ig_3 PF13927.4 001305952.1_10823001_1 - 0.038 14.5 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.14 001305952.1_10823001_1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain HD PF01966.20 001305824.1_30124001_1 - 4.1e-18 65.6 0.0 1.7e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 HD domain SAM_1 PF00536.28 001305824.1_30124001_1 - 6.3e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 001305824.1_30124001_1 - 8.8e-09 35.2 0.0 1.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001305824.1_30124001_1 - 0.008 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ste50p-SAM PF09235.8 001305824.1_30124001_1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif HD PF01966.20 001305948.1_10824001_1 - 6.2e-18 65.0 0.0 1.7e-17 63.6 0.0 1.8 2 0 0 2 2 2 1 HD domain SAM_2 PF07647.15 001305948.1_10824001_1 - 5.3e-09 35.9 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001305948.1_10824001_1 - 8.4e-09 35.6 0.0 2.2e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001305948.1_10824001_1 - 0.0077 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.20 001305839.1_13124001_1 - 1.2e-17 64.2 0.0 3.4e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 HD domain SAM_2 PF07647.15 001305839.1_13124001_1 - 2.2e-09 37.2 0.0 4.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001305839.1_13124001_1 - 6.8e-09 35.9 0.0 2.1e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001305839.1_13124001_1 - 0.008 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ste50p-SAM PF09235.8 001305839.1_13124001_1 - 0.055 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif V-set PF07686.15 001305974.1_10824001_3 - 6.1e-20 71.3 2.2 4.3e-15 55.7 0.2 4.7 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_2 PF13895.4 001305974.1_10824001_3 - 3.8e-16 59.1 2.0 2.7e-06 27.5 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.4 001305974.1_10824001_3 - 1.6e-14 54.1 6.6 1.6e-07 31.7 0.0 5.2 4 1 2 6 6 6 3 Immunoglobulin domain ig PF00047.23 001305974.1_10824001_3 - 3.2e-11 43.1 3.1 0.00099 19.1 0.0 4.5 5 1 0 5 5 5 3 Immunoglobulin domain I-set PF07679.14 001305974.1_10824001_3 - 2.1e-09 37.2 0.0 0.00072 19.4 0.0 4.3 4 1 0 4 4 4 2 Immunoglobulin I-set domain C2-set_2 PF08205.10 001305974.1_10824001_3 - 4.6e-08 32.9 4.9 0.00026 20.8 0.1 4.3 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.13 001305974.1_10824001_3 - 0.032 14.6 0.0 3.6 8.0 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Syndecan PF01034.18 001305974.1_10824001_3 - 1.6 8.6 3.2 1.2 9.0 0.9 1.9 2 0 0 2 2 2 0 Syndecan domain LST1 PF05083.11 001305974.1_10824001_3 - 3.5 7.8 4.6 2.6 8.3 0.1 2.3 2 0 0 2 2 2 0 LST-1 protein IL6 PF00489.15 001310092.1_36222001_1 - 6.5e-56 188.7 1.7 7.7e-56 188.5 1.7 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family Pkinase_Tyr PF07714.15 001317070.1_52128001_1 - 2.1e-86 289.3 0.0 3.1e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.22 001317070.1_52128001_1 - 1.8e-55 185.7 0.0 1.1e-31 109.0 0.0 2.3 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.4 001317070.1_52128001_1 - 3e-44 149.9 75.2 8e-41 138.8 27.2 3.7 2 1 2 4 4 4 3 Growth factor receptor domain IV Pkinase PF00069.23 001317070.1_52128001_1 - 5e-37 127.5 0.0 7.2e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.18 001317070.1_52128001_1 - 7.4e-28 97.2 82.5 6e-25 87.7 36.8 4.1 2 1 2 4 4 4 3 Furin-like cysteine rich region APH PF01636.21 001317070.1_52128001_1 - 0.011 15.5 0.9 0.024 14.4 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family CBP_BcsF PF11120.6 001317070.1_52128001_1 - 0.66 9.9 5.3 0.3 11.0 2.4 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF Ig_5 PF16681.3 001310174.1_33422001_1 - 1.6e-28 98.8 1.7 2.5e-28 98.2 1.7 1.3 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.3 001310174.1_33422001_1 - 4.1e-21 75.0 0.9 6.5e-21 74.3 0.9 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Ig_2 PF13895.4 001310174.1_33422001_1 - 1.3e-05 25.4 0.9 1.6e-05 25.0 0.1 1.5 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.4 001310174.1_33422001_1 - 4e-05 24.0 0.7 0.00012 22.4 0.2 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ITAM PF02189.13 001310174.1_33422001_1 - 4.5e-05 23.5 0.7 7.6e-05 22.8 0.7 1.4 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif ig PF00047.23 001310174.1_33422001_1 - 0.006 16.6 1.4 0.033 14.2 0.9 2.2 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.14 001310174.1_33422001_1 - 0.029 14.3 0.5 0.11 12.5 0.5 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain P5-ATPase PF12409.6 001310174.1_33422001_1 - 0.065 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 P5-type ATPase cation transporter IL12 PF03039.12 001290878.1_07322001_2 - 6.4e-114 378.6 6.5 7.2e-114 378.4 6.5 1.0 1 0 0 1 1 1 1 Interleukin-12 alpha subunit Nup153 PF08604.8 001308667.1_35729001_1 - 1.5e-216 720.0 44.9 1.5e-216 720.0 44.9 5.3 3 2 0 4 4 4 1 Nucleoporin Nup153-like zf-RanBP PF00641.16 001308667.1_35729001_1 - 5.1e-44 147.1 38.4 2.2e-12 45.9 1.0 4.6 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Nup_retrotrp_bd PF10599.7 001308667.1_35729001_1 - 3.6e-24 85.1 20.3 3.6e-24 85.1 20.3 12.4 5 3 3 8 8 8 1 Retro-transposon transporting motif Vps36-NZF-N PF16988.3 001308667.1_35729001_1 - 0.075 12.3 20.6 3.1 7.1 3.0 4.9 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain HTH_IclR PF09339.8 001308667.1_35729001_1 - 0.15 11.8 0.1 0.33 10.7 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Collagen PF01391.16 001323780.1_20929001_1 - 1.6e-165 536.9 665.5 7.9e-09 35.0 26.3 21.1 2 1 18 20 20 20 17 Collagen triple helix repeat (20 copies) COLFI PF01410.16 001323780.1_20929001_1 - 3.1e-107 357.0 0.1 3.8e-107 356.8 0.1 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Pkinase PF00069.23 001290926.1_07324001_1 - 3.9e-36 124.6 0.0 5.7e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001290926.1_07324001_1 - 1.8e-34 119.1 0.0 2.5e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.10 001290926.1_07324001_1 - 2.7e-17 61.8 0.4 5.3e-17 60.9 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.21 001290926.1_07324001_1 - 1e-09 39.2 11.0 1e-09 39.2 11.0 1.9 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.21 001290926.1_07324001_1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.4 001290926.1_07324001_1 - 0.1 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Integrin_beta PF00362.16 001303517.1_08425001_1 - 8.4e-108 359.6 0.0 1.3e-107 359.0 0.0 1.3 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.9 001303517.1_08425001_1 - 3.8e-20 71.2 0.1 6.8e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.10 001303517.1_08425001_1 - 6.2e-17 61.7 8.0 6.2e-17 61.7 8.0 3.6 3 1 0 3 3 3 1 Integrin beta tail domain PSI_integrin PF17205.1 001303517.1_08425001_1 - 9e-15 54.1 4.5 9e-15 54.1 4.5 5.0 5 1 0 5 5 5 1 Integrin plexin domain EGF_2 PF07974.11 001303517.1_08425001_1 - 6.7e-08 32.6 97.0 4.3e-05 23.6 17.2 6.5 5 2 1 6 6 6 4 EGF-like domain 7tm_1 PF00001.19 001305956.1_10823001_1 - 8.2e-49 166.1 24.7 1.5e-48 165.2 24.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001305956.1_10823001_1 - 3.4e-12 46.2 23.1 4.4e-12 45.8 23.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM223 PF14640.4 001305956.1_10823001_1 - 0.073 13.1 1.6 0.26 11.3 0.7 2.2 1 1 1 2 2 2 0 Transmembrane protein 223 NIF PF03031.16 001310205.1_33423001_1 - 1.9e-53 180.3 0.0 2.7e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ATP-gua_Ptrans PF00217.17 001290723.1_42224001_3 - 2.4e-94 315.4 0.0 3.1e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.13 001290723.1_42224001_3 - 2.5e-35 120.6 0.0 4.7e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain NAC PF01849.16 001330263.1_11722001_1 - 3.5e-25 87.7 1.0 1.1e-24 86.0 0.3 2.2 2 0 0 2 2 2 1 NAC domain HTH_13 PF11972.6 001330263.1_11722001_1 - 0.21 11.5 0.6 12 5.9 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain RNA_pol_Rpo13 PF12136.6 001330263.1_11722001_1 - 4 7.3 10.3 0.13 12.0 3.9 1.9 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain ATP-gua_Ptrans PF00217.17 001290724.1_42223001_2 - 1.3e-93 313.1 0.0 1.6e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.13 001290724.1_42223001_2 - 7.2e-33 112.7 0.0 1.6e-32 111.6 0.0 1.6 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain Fer4_2 PF12797.5 001290724.1_42223001_3 - 0.0078 16.1 0.2 0.024 14.6 0.2 1.9 1 0 0 1 1 1 1 4Fe-4S binding domain Glyco_transf_41 PF13844.4 001290907.1_07327001_3 - 4.6e-254 842.9 0.0 6e-254 842.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.26 001290907.1_07327001_3 - 8.5e-97 313.3 29.8 2.7e-10 39.5 0.3 13.7 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_11 PF13414.4 001290907.1_07327001_3 - 1.3e-89 293.5 36.3 9.4e-11 41.1 0.4 12.8 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.15 001290907.1_07327001_3 - 2.4e-73 236.3 29.2 2.5e-08 33.3 0.4 13.1 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_17 PF13431.4 001290907.1_07327001_3 - 8.3e-68 219.9 29.3 1.7e-05 24.8 0.1 13.6 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_8 PF13181.4 001290907.1_07327001_3 - 1.1e-66 215.4 13.2 1.1e-06 28.3 0.1 13.4 14 0 0 14 14 13 11 Tetratricopeptide repeat TPR_12 PF13424.4 001290907.1_07327001_3 - 3.8e-48 161.5 29.6 1.1e-10 41.5 0.4 9.5 6 2 4 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.4 001290907.1_07327001_3 - 2.2e-46 152.4 18.3 0.00037 20.9 0.1 12.2 5 3 7 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.4 001290907.1_07327001_3 - 3e-44 149.3 16.8 6.2e-09 36.3 0.1 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.4 001290907.1_07327001_3 - 6.8e-43 144.9 22.0 3.8e-07 30.4 0.5 9.6 3 3 5 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.4 001290907.1_07327001_3 - 1.6e-42 140.2 17.2 6.5e-05 22.5 0.0 12.9 13 1 1 14 14 13 10 Tetratricopeptide repeat TPR_10 PF13374.4 001290907.1_07327001_3 - 2e-39 132.3 47.4 6.6e-07 28.9 0.4 12.2 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_9 PF13371.4 001290907.1_07327001_3 - 3.9e-17 62.1 16.7 0.001 19.1 0.4 6.8 5 1 3 8 8 7 6 Tetratricopeptide repeat TPR_6 PF13174.4 001290907.1_07327001_3 - 4.1e-15 55.2 15.2 0.46 11.1 0.0 10.6 11 0 0 11 11 10 2 Tetratricopeptide repeat NARP1 PF12569.6 001290907.1_07327001_3 - 3.4e-14 52.5 5.5 0.0011 17.8 0.0 5.6 1 1 4 5 5 5 3 NMDA receptor-regulated protein 1 TPR_4 PF07721.12 001290907.1_07327001_3 - 1.5e-13 49.8 11.2 1.5 9.6 0.2 9.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.4 001290907.1_07327001_3 - 4.9e-10 38.9 8.6 1.5e-05 24.2 0.7 4.7 1 1 2 4 4 4 2 Tetratricopeptide repeat FAT PF02259.21 001290907.1_07327001_3 - 7e-08 31.9 0.1 0.21 10.6 0.3 5.7 2 2 2 4 4 4 2 FAT domain MIT PF04212.16 001290907.1_07327001_3 - 1.9e-07 30.9 20.8 0.11 12.4 0.0 8.6 7 1 2 9 9 8 2 MIT (microtubule interacting and transport) domain TPR_21 PF09976.7 001290907.1_07327001_3 - 2.1e-06 27.5 10.9 0.14 11.7 0.0 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat-like domain TPR_3 PF07720.10 001290907.1_07327001_3 - 3.2e-06 26.9 1.0 1.2 9.0 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat Wzy_C_2 PF11846.6 001290907.1_07327001_3 - 5.4e-05 23.1 11.3 0.01 15.6 0.3 4.5 4 1 0 5 5 4 1 Virulence factor membrane-bound polymerase, C-terminal SNAP PF14938.4 001290907.1_07327001_3 - 0.00051 19.4 16.1 0.042 13.1 3.3 4.6 1 1 3 5 5 5 2 Soluble NSF attachment protein, SNAP BTAD PF03704.15 001290907.1_07327001_3 - 0.00067 20.0 16.6 0.33 11.2 0.5 5.7 3 2 2 5 5 5 2 Bacterial transcriptional activator domain SHNi-TPR PF10516.7 001290907.1_07327001_3 - 0.0015 17.9 1.6 12 5.3 0.0 5.5 7 0 0 7 7 7 0 SHNi-TPR EST1_DNA_bind PF10373.7 001290907.1_07327001_3 - 0.004 16.6 13.0 0.48 9.7 0.1 4.6 5 0 0 5 5 5 2 Est1 DNA/RNA binding domain RPN7 PF10602.7 001290907.1_07327001_3 - 0.0055 16.2 8.7 19 4.7 0.1 6.8 5 2 4 9 9 9 0 26S proteasome subunit RPN7 Tcf25 PF04910.12 001290907.1_07327001_3 - 0.035 13.1 0.1 0.13 11.2 0.0 1.9 2 0 0 2 2 2 0 Transcriptional repressor TCF25 ANAPC3 PF12895.5 001290907.1_07327001_3 - 0.065 13.3 16.9 0.089 12.9 1.0 5.1 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.10 001290907.1_07327001_3 - 0.071 12.7 0.4 37 3.9 0.0 3.8 3 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.4 001290907.1_07327001_3 - 0.094 12.7 0.7 1 9.3 0.0 3.2 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.4 001290907.1_07327001_3 - 0.14 12.5 1.2 24 5.3 0.2 3.1 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation Mad3_BUB1_I PF08311.10 001290907.1_07327001_3 - 0.28 11.0 7.9 94 2.9 0.2 6.3 6 1 2 8 8 7 0 Mad3/BUB1 homology region 1 DUF627 PF04781.10 001290907.1_07327001_3 - 0.4 10.6 3.8 11 6.0 0.0 4.4 3 1 3 6 6 5 0 Protein of unknown function (DUF627) TPR_20 PF14561.4 001290907.1_07327001_3 - 0.6 10.4 14.7 1.6 9.0 0.1 5.9 4 2 3 8 8 8 0 Tetratricopeptide repeat Trypsin PF00089.24 001305934.1_29722001_2 - 9.1e-65 218.4 0.1 1.1e-64 218.2 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001305934.1_29722001_2 - 6.4e-08 33.5 0.0 1e-07 32.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain LRR_8 PF13855.4 001135930.1_39526001_1 - 2.2e-53 177.7 56.4 9.8e-13 47.5 1.8 10.4 3 3 8 12 12 12 12 Leucine rich repeat TIR PF01582.18 001135930.1_39526001_1 - 6.7e-33 113.8 0.1 1.2e-32 113.0 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001135930.1_39526001_1 - 1.3e-31 107.8 53.3 1.8e-07 31.1 1.0 10.2 6 2 2 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001135930.1_39526001_1 - 2.5e-14 51.3 49.8 0.41 11.2 0.0 15.8 15 1 0 15 15 15 5 Leucine Rich Repeat LRR_9 PF14580.4 001135930.1_39526001_1 - 3.9e-11 42.6 18.8 0.0013 18.1 0.1 5.0 2 2 3 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.4 001135930.1_39526001_1 - 7.9e-10 38.7 10.9 6.6e-05 22.7 0.1 4.7 2 2 3 5 5 5 3 Leucine rich repeats (6 copies) TIR_2 PF13676.4 001135930.1_39526001_1 - 5e-09 36.3 0.1 9e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001135930.1_39526001_1 - 2.3e-07 30.2 50.1 0.33 11.0 0.4 13.2 14 0 0 14 14 14 3 Leucine Rich repeat DUF1863 PF08937.9 001135930.1_39526001_1 - 3.9e-05 23.8 0.3 0.00015 21.9 0.3 1.9 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) CBP_BcsR PF10945.6 001135930.1_39526001_1 - 0.27 10.6 1.7 0.87 9.0 0.2 2.7 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR Gtr1_RagA PF04670.10 001161867.1_39523001_1 - 6.5e-73 244.8 0.9 8.5e-73 244.4 0.9 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.11 001161867.1_39523001_1 - 4.7e-05 23.5 0.0 7.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001161867.1_39523001_1 - 7e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001161867.1_39523001_1 - 0.00036 19.9 0.0 0.0006 19.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.20 001161867.1_39523001_1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.4 001161867.1_39523001_1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.4 001161867.1_39523001_1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.21 001161867.1_39523001_1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Crystallin PF00525.16 001173076.1_09922001_3 - 3.4e-29 100.7 7.5 6.6e-29 99.8 7.5 1.5 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.19 001173076.1_09922001_3 - 6.6e-25 87.1 0.1 8.6e-25 86.7 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PAS_3 PF08447.10 001173054.1_09926001_2 - 6.5e-20 71.1 0.2 1.4e-13 50.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001173054.1_09926001_2 - 3.7e-15 55.9 0.1 5.9e-12 45.6 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 001173054.1_09926001_2 - 5.2e-15 55.3 0.1 2.5e-13 49.9 0.0 2.8 3 0 0 3 3 3 1 PAS fold HLH PF00010.24 001173054.1_09926001_2 - 1.2e-05 25.1 0.2 2.5e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001173054.1_09926001_2 - 0.054 13.6 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 PAS domain PAS_4 PF08448.8 001173054.1_09926001_2 - 0.13 12.3 0.1 0.95 9.6 0.0 2.2 2 0 0 2 2 2 0 PAS fold SOBP PF15279.4 001104534.1_29626001_1 - 1.2e-90 305.2 38.2 1.2e-90 305.2 38.2 3.8 3 1 1 4 4 4 1 Sine oculis-binding protein zf-FCS PF06467.12 001104534.1_29626001_1 - 4.6e-05 23.2 9.4 0.016 15.0 1.3 2.9 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-C6H2 PF15801.3 001104534.1_29626001_1 - 0.18 12.0 5.4 0.35 11.1 1.7 2.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding DUF4834 PF16118.3 001133986.1_43527001_3 - 0.057 14.2 1.6 0.22 12.4 1.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.11 001133986.1_43527001_3 - 7.5 6.3 16.9 14 5.4 16.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Crystall PF00030.17 001173071.1_09922001_3 - 2e-59 197.6 0.2 2.6e-30 104.3 0.0 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001173071.1_09922001_3 - 6.4e-06 25.9 0.0 0.029 14.2 0.0 2.5 2 0 0 2 2 2 2 Peptidase inhibitor family I36 Crystall_3 PF08964.8 001173071.1_09922001_3 - 2.5e-05 24.2 0.2 0.18 11.8 0.1 3.3 3 0 0 3 3 3 2 Beta/Gamma crystallin F-box-like PF12937.5 001129739.1_39523001_1 - 4.5e-08 32.7 1.7 1e-07 31.6 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.31 001129739.1_39523001_1 - 2.7e-07 30.1 2.8 3.4e-07 29.8 0.2 2.6 3 0 0 3 3 3 1 F-box domain DUF4116 PF13475.4 001129739.1_39523001_1 - 0.0076 15.8 0.6 0.026 14.1 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4116) TACI-CRD2 PF09305.8 001261540.1_29623001_2 - 0.79 9.7 5.0 0.2 11.6 1.0 2.1 2 0 0 2 2 2 0 TACI, cysteine-rich domain Synuclein PF01387.15 001261540.1_29623001_3 - 1.5e-48 164.2 10.2 3.7e-48 163.0 10.2 1.6 1 1 0 1 1 1 1 Synuclein TIR_2 PF13676.4 001279203.1_39622001_1 - 1e-10 41.7 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001279203.1_39622001_1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain IIGP PF05049.11 001289893.1_35724001_1 - 6.4e-61 206.3 0.1 8.1e-61 206.0 0.1 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pkinase PF00069.23 001287200.1_52722001_1 - 1.4e-74 250.6 0.0 1.6e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001287200.1_52722001_1 - 5.5e-34 117.5 0.0 7e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001287200.1_52722001_1 - 0.0026 17.0 0.0 0.066 12.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.9 001287200.1_52722001_1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.21 001287200.1_52722001_1 - 0.038 13.8 0.0 0.086 12.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Insulin PF00049.16 001280873.1_29221001_1 - 8.9e-09 36.1 0.8 2.7e-08 34.6 0.8 1.7 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001280873.1_29221001_1 - 0.002 18.0 3.3 0.035 14.0 0.8 2.3 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type 7tm_4 PF13853.4 001279243.1_39622001_1 - 3.9e-55 187.4 22.0 4.6e-55 187.2 22.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001279243.1_39622001_1 - 2.3e-25 89.2 27.4 5.3e-25 88.0 27.4 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001279243.1_39622001_1 - 0.0001 21.7 23.0 0.00015 21.1 23.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001279243.1_39622001_1 - 0.0005 19.3 21.5 0.00066 18.9 21.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SLC3A2_N PF16028.3 001279243.1_39622001_1 - 2.5 7.6 4.5 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Heme_oxygenase PF01126.18 001286597.1_40023001_3 - 2.4e-80 269.0 2.8 2.9e-80 268.8 2.8 1.1 1 0 0 1 1 1 1 Heme oxygenase Cyclin_N PF00134.21 001244388.1_49828001_3 - 4.9e-14 52.1 0.2 7.7e-14 51.5 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.9 001244388.1_49828001_3 - 7.6e-11 42.5 0.0 1.2e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin Interferon PF00143.17 001031832.1_22422001_1 - 4.2e-58 195.9 0.1 4.8e-58 195.7 0.1 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain TGF_beta PF00019.18 001285581.1_09023001_1 - 1.3e-31 109.4 1.6 2.8e-31 108.4 1.6 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 001285581.1_09023001_1 - 1.9e-09 37.5 0.5 1.4e-08 34.7 0.5 2.2 1 1 0 1 1 1 1 TGF-beta propeptide Insulin PF00049.16 001280868.1_29222001_1 - 3.9e-10 40.5 3.2 2.6e-09 37.8 3.2 2.1 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001280868.1_29222001_1 - 0.00078 19.3 6.5 0.039 13.8 0.1 2.9 3 0 0 3 3 3 2 Nematode insulin-related peptide beta type Arf PF00025.19 103708.1_26223120_3 - 8.4e-30 103.4 0.0 1.2e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 103708.1_26223120_3 - 3.7e-09 36.1 0.1 6.6e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.11 103708.1_26223120_3 - 5.8e-06 26.4 0.0 1.3e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.18 103708.1_26223120_3 - 0.00027 20.1 0.1 0.13 11.2 0.0 2.5 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.20 103708.1_26223120_3 - 0.00037 20.0 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 Ras family AAA_15 PF13175.4 103708.1_26223120_3 - 0.0062 16.1 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.21 103708.1_26223120_3 - 0.032 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.4 103708.1_26223120_3 - 0.038 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IL10 PF00726.15 001303520.1_08422001_1 - 9.2e-107 353.9 0.7 1.1e-106 353.7 0.7 1.0 1 0 0 1 1 1 1 Interleukin 10 IL22 PF14565.4 001303520.1_08422001_1 - 7.7e-08 32.6 0.2 1e-07 32.2 0.2 1.1 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor Helicase_IV_N PF12462.6 001303520.1_08422001_1 - 0.095 12.5 0.1 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal IL7 PF01415.14 001292079.1_11722001_3 - 7.1e-47 158.7 3.9 9.8e-47 158.2 3.9 1.2 1 0 0 1 1 1 1 Interleukin 7/9 family LRR_8 PF13855.4 001320279.1_44826001_1 - 5.4e-38 128.4 56.5 2.3e-12 46.4 9.9 8.9 6 3 2 9 9 9 7 Leucine rich repeat TIR PF01582.18 001320279.1_44826001_1 - 4.1e-22 78.7 0.3 8.4e-22 77.7 0.3 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001320279.1_44826001_1 - 5.7e-21 74.0 59.6 1.3e-05 25.2 2.9 9.6 8 1 2 10 10 10 5 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001320279.1_44826001_1 - 4.1e-10 39.8 0.0 7.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001320279.1_44826001_1 - 1.2e-08 34.6 20.6 0.0013 18.2 0.2 4.8 2 2 1 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.4 001320279.1_44826001_1 - 0.00025 20.7 38.9 1.7 8.8 0.0 10.6 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.31 001320279.1_44826001_1 - 0.0013 18.8 45.7 0.63 10.6 1.4 12.2 13 0 0 13 13 13 2 Leucine Rich Repeat LRRCT PF01463.22 001320279.1_44826001_1 - 0.0078 16.5 0.1 0.026 14.9 0.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain DUF1863 PF08937.9 001320279.1_44826001_1 - 0.08 13.1 0.4 0.3 11.3 0.4 1.9 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) TIR PF01582.18 001290161.1_44827001_3 - 4.5e-27 94.8 0.4 7.6e-27 94.1 0.4 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001290161.1_44827001_3 - 3.5e-19 68.2 37.3 7.9e-09 35.0 1.9 7.9 4 2 5 9 9 9 7 Leucine rich repeat LRR_4 PF12799.5 001290161.1_44827001_3 - 4.1e-13 49.1 45.6 0.00015 21.9 0.8 9.2 7 3 1 10 10 10 5 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001290161.1_44827001_3 - 1.4e-11 44.5 0.0 2.7e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001290161.1_44827001_3 - 4e-05 23.0 9.7 0.02 14.3 0.0 3.4 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.4 001290161.1_44827001_3 - 1.2 9.3 26.9 9.6 6.4 0.1 9.9 11 0 0 11 11 11 0 Leucine Rich repeat DUF4605 PF15378.4 001290161.1_44827001_3 - 1.9 8.3 5.0 37 4.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4605) LRR_8 PF13855.4 001290164.1_44828001_2 - 9.7e-64 210.9 97.0 6.5e-10 38.5 1.3 15.4 10 3 5 15 15 15 13 Leucine rich repeat LRR_4 PF12799.5 001290164.1_44828001_2 - 4e-30 103.1 96.3 8e-06 25.9 0.6 14.5 7 3 8 15 15 15 13 Leucine Rich repeats (2 copies) TIR PF01582.18 001290164.1_44828001_2 - 2.6e-12 46.8 0.2 4.2e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001290164.1_44828001_2 - 3.2e-06 26.6 42.8 0.01 15.2 0.7 6.9 4 3 3 7 7 7 4 Leucine-rich repeat LRR_1 PF00560.31 001290164.1_44828001_2 - 1.6e-05 24.5 84.3 4.5 8.0 1.7 21.0 21 5 1 22 22 22 6 Leucine Rich Repeat LRR_6 PF13516.4 001290164.1_44828001_2 - 0.00011 21.8 61.8 1.8 8.7 0.1 16.3 18 0 0 18 18 18 4 Leucine Rich repeat TIR_2 PF13676.4 001290164.1_44828001_2 - 0.00063 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.16 001290164.1_44828001_2 - 0.036 13.6 3.9 0.087 12.4 0.1 3.6 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain Prot_inhib_II PF02428.13 001303548.1_08521001_1 - 1.4 9.2 7.0 0.12 12.7 1.8 1.9 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family IL2 PF00715.15 001303548.1_08521001_2 - 1.2e-76 255.4 6.8 1.3e-76 255.3 6.8 1.0 1 0 0 1 1 1 1 Interleukin 2 Baculo_PEP_C PF04513.10 001303548.1_08521001_2 - 0.013 15.4 1.6 0.017 15.0 1.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_8 PF13855.4 001320280.1_44828001_1 - 5.5e-53 176.5 59.9 1.3e-11 44.0 1.2 9.9 7 3 3 11 11 11 10 Leucine rich repeat TIR PF01582.18 001320280.1_44828001_1 - 5.2e-29 101.1 0.2 8.1e-29 100.5 0.2 1.2 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001320280.1_44828001_1 - 2.9e-22 78.2 50.4 5.5e-05 23.3 0.3 10.7 6 3 7 13 13 13 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001320280.1_44828001_1 - 1.8e-11 43.9 0.7 2.5e-06 27.4 0.3 3.7 4 1 0 4 4 4 2 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001320280.1_44828001_1 - 1.4e-10 40.9 16.1 0.15 11.4 0.1 5.7 3 2 3 6 6 6 4 Leucine-rich repeat TIR_2 PF13676.4 001320280.1_44828001_1 - 8.5e-08 32.3 0.1 1.7e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001320280.1_44828001_1 - 0.0046 16.8 24.0 29 4.9 0.0 10.8 11 0 0 11 11 11 0 Leucine Rich repeat LRR_1 PF00560.31 001320280.1_44828001_1 - 0.022 15.0 37.8 10 6.9 0.1 12.8 12 2 0 12 12 12 0 Leucine Rich Repeat TGFb_propeptide PF00688.16 001290071.1_52723001_3 - 3.8e-40 138.1 0.0 5.1e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 001290071.1_52723001_3 - 2.3e-22 79.7 1.6 4.3e-22 78.8 1.6 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain EF-hand_1 PF00036.30 001320172.1_39924001_2 - 1.9e-20 70.6 18.2 0.00035 19.8 0.1 6.5 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.4 001320172.1_39924001_2 - 1.6e-18 64.9 14.1 0.0014 18.2 0.0 6.4 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.4 001320172.1_39924001_2 - 8.2e-14 51.7 24.6 0.00013 22.2 3.4 4.9 3 1 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.4 001320172.1_39924001_2 - 2.7e-09 36.0 27.9 0.0047 16.3 0.1 6.4 6 1 0 6 6 6 3 EF hand EF-hand_8 PF13833.4 001320172.1_39924001_2 - 1.8e-05 24.2 16.4 0.3 10.7 0.0 6.1 6 0 0 6 6 6 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001320172.1_39924001_2 - 0.18 12.0 13.2 1.9 8.7 1.1 3.3 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2229 PF09989.7 001320172.1_39924001_3 - 0.078 12.5 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) IL10 PF00726.15 001290845.1_07322001_1 - 7.3e-108 357.4 0.6 8.3e-108 357.3 0.6 1.0 1 0 0 1 1 1 1 Interleukin 10 IL22 PF14565.4 001290845.1_07322001_1 - 6.2e-07 29.6 0.1 7.9e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor Helicase_IV_N PF12462.6 001290845.1_07322001_1 - 0.05 13.4 0.2 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal IL4 PF00727.16 001303554.1_08521001_1 - 5.3e-48 161.7 6.4 6.5e-48 161.4 6.4 1.1 1 0 0 1 1 1 1 Interleukin 4 DUF4942 PF13708.4 001303554.1_08521001_1 - 0.011 15.6 0.1 0.013 15.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4942) DUF1732 PF08340.9 001303554.1_08521001_1 - 0.026 14.4 0.2 0.089 12.7 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) SecIII_SopE_N PF05364.12 001303554.1_08521001_1 - 0.087 12.8 0.1 0.23 11.4 0.0 1.6 1 1 1 2 2 2 0 Salmonella type III secretion SopE effector N-terminus Yip1 PF04893.15 001290580.1_39922001_3 - 9e-07 28.6 18.7 1.3e-06 28.1 18.5 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.13 001290580.1_39922001_3 - 9.1e-05 21.9 10.0 0.0061 16.0 9.6 2.1 1 1 0 1 1 1 1 YIF1 Romo1 PF10247.7 001290580.1_39922001_3 - 0.012 15.8 1.3 0.032 14.4 1.3 1.8 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 LRR_8 PF13855.4 001320282.1_44827001_1 - 2.1e-87 286.7 62.2 6.1e-14 51.4 2.0 15.3 10 5 5 15 15 15 14 Leucine rich repeat LRR_4 PF12799.5 001320282.1_44827001_1 - 3.2e-42 141.5 59.1 0.00033 20.8 0.1 15.8 9 3 7 17 17 17 16 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001320282.1_44827001_1 - 1.3e-15 55.2 53.6 1.4 9.6 0.0 22.4 22 3 1 23 23 23 2 Leucine Rich Repeat LRR_6 PF13516.4 001320282.1_44827001_1 - 8.2e-08 31.6 66.5 1.5 8.9 1.2 18.9 21 0 0 21 21 21 5 Leucine Rich repeat TIR PF01582.18 001320282.1_44827001_1 - 2.2e-06 27.5 0.0 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001320282.1_44827001_1 - 0.0017 17.8 11.6 0.46 9.8 0.1 5.9 4 2 2 7 7 7 2 Leucine-rich repeat FNIP PF05725.10 001320282.1_44827001_1 - 0.0071 16.4 3.2 2.7 8.1 0.0 4.7 5 2 1 6 6 6 1 FNIP Repeat TIR_2 PF13676.4 001320282.1_44827001_1 - 0.43 10.8 1.6 1.6 8.9 1.6 1.9 1 1 0 1 1 1 0 TIR domain IL7 PF01415.14 001292075.1_11722001_3 - 9.2e-46 155.1 2.5 1.1e-45 154.9 2.5 1.0 1 0 0 1 1 1 1 Interleukin 7/9 family IL4 PF00727.16 001303522.1_08421001_1 - 5.5e-48 161.6 6.4 6.5e-48 161.4 6.4 1.1 1 0 0 1 1 1 1 Interleukin 4 DUF4942 PF13708.4 001303522.1_08421001_1 - 0.011 15.5 0.1 0.013 15.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4942) DUF1732 PF08340.9 001303522.1_08421001_1 - 0.028 14.3 0.2 0.099 12.5 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) Nipped-B_C PF12830.5 001303522.1_08421001_1 - 0.058 13.2 0.9 0.23 11.2 0.9 1.8 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus SecIII_SopE_N PF05364.12 001303522.1_08421001_1 - 0.088 12.8 0.1 0.23 11.4 0.0 1.6 1 1 1 2 2 2 0 Salmonella type III secretion SopE effector N-terminus Macro PF01661.19 001305950.1_10825001_1 - 3.3e-46 156.0 0.1 5.4e-29 100.5 0.0 2.5 2 0 0 2 2 2 2 Macro domain PARP PF00644.18 001305950.1_10825001_1 - 3.3e-05 23.5 0.1 0.0012 18.4 0.0 2.8 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain LRR_8 PF13855.4 001290160.1_44827001_1 - 3.5e-25 87.4 44.7 8.6e-14 50.9 4.2 6.6 4 3 3 7 7 7 5 Leucine rich repeat TIR PF01582.18 001290160.1_44827001_1 - 6.1e-20 71.6 0.1 1.2e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001290160.1_44827001_1 - 1.5e-16 60.0 48.7 7.4e-07 29.2 0.6 8.8 4 3 7 11 11 11 9 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001290160.1_44827001_1 - 2.7e-09 37.1 0.0 4.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001290160.1_44827001_1 - 1.9e-05 24.3 41.4 2.1 9.0 0.1 11.2 7 3 2 9 9 9 3 Leucine Rich Repeat LRR_9 PF14580.4 001290160.1_44827001_1 - 3.2e-05 23.4 15.9 0.091 12.1 0.1 3.6 3 1 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.4 001290160.1_44827001_1 - 0.00047 19.9 35.8 3 8.0 1.7 9.9 11 0 0 11 11 11 2 Leucine Rich repeat CSN8_PSD8_EIF3K PF10075.7 001290160.1_44827001_1 - 0.038 13.9 0.4 3.1 7.6 0.0 3.0 3 0 0 3 3 3 0 CSN8/PSMD8/EIF3K family DUF1863 PF08937.9 001290160.1_44827001_1 - 0.057 13.6 0.0 1.4 9.1 0.1 2.2 1 1 1 2 2 2 0 MTH538 TIR-like domain (DUF1863) Pkinase PF00069.23 001290168.1_44824001_1 - 8.9e-56 189.0 0.1 1.9e-55 187.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001290168.1_44824001_1 - 1.2e-35 122.9 0.4 4.8e-35 121.0 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase dsrm PF00035.24 001290168.1_44824001_1 - 1.1e-24 86.7 4.9 3.8e-12 46.6 0.1 3.0 3 0 0 3 3 3 2 Double-stranded RNA binding motif Kdo PF06293.12 001290168.1_44824001_1 - 0.00016 20.9 0.0 0.00036 19.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DND1_DSRM PF14709.5 001290168.1_44824001_1 - 0.018 15.1 0.1 0.36 11.0 0.0 2.6 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 APH PF01636.21 001290168.1_44824001_1 - 0.026 14.3 0.0 1.5 8.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.4 001290168.1_44824001_1 - 0.03 13.5 0.0 0.07 12.3 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.9 001290168.1_44824001_1 - 0.076 11.8 4.3 4.9 5.9 0.1 3.0 3 0 0 3 3 3 0 Poxvirus serine/threonine protein kinase GrpE PF01025.17 001294290.1_39922001_3 - 2.4e-38 131.3 0.0 2.9e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 GrpE GOLGA2L5 PF15070.4 001294290.1_39922001_3 - 0.00072 18.2 0.1 0.00089 17.9 0.1 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Laminin_I PF06008.12 001294290.1_39922001_3 - 0.028 14.0 0.2 0.038 13.6 0.2 1.1 1 0 0 1 1 1 0 Laminin Domain I 7tm_4 PF13853.4 001309002.1_29722001_1 - 3.2e-52 177.9 22.6 3.7e-52 177.7 22.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001309002.1_29722001_1 - 9.9e-24 83.9 27.5 2.2e-23 82.7 27.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001309002.1_29722001_1 - 2.6e-05 23.6 22.0 4.4e-05 22.8 22.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_8 PF13855.4 001290172.1_44826001_3 - 2.6e-46 155.1 54.0 2.2e-11 43.2 0.8 10.8 7 3 5 12 12 12 9 Leucine rich repeat TIR PF01582.18 001290172.1_44826001_3 - 6.7e-33 113.8 0.2 1.1e-32 113.2 0.2 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001290172.1_44826001_3 - 2e-27 94.5 57.2 7.6e-07 29.2 2.5 11.0 4 2 9 14 14 14 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001290172.1_44826001_3 - 4.9e-12 45.6 15.5 0.00069 19.0 0.1 5.2 2 2 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.31 001290172.1_44826001_3 - 5.7e-12 44.2 51.0 1.3 9.6 0.1 15.5 15 2 0 15 15 15 5 Leucine Rich Repeat LRR_6 PF13516.4 001290172.1_44826001_3 - 1.1e-09 37.4 48.0 0.84 9.7 0.1 14.0 15 0 0 15 15 15 4 Leucine Rich repeat LRR_5 PF13306.4 001290172.1_44826001_3 - 1.4e-09 37.8 11.0 0.00052 19.8 0.0 5.0 2 2 4 6 6 6 4 Leucine rich repeats (6 copies) TIR_2 PF13676.4 001290172.1_44826001_3 - 5e-09 36.3 0.1 9.4e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.9 001290172.1_44826001_3 - 0.0021 18.3 0.2 0.0083 16.3 0.2 1.9 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) Curto_V2 PF07325.9 001290172.1_44826001_3 - 0.031 14.0 0.2 0.078 12.7 0.2 1.6 1 0 0 1 1 1 0 Curtovirus V2 protein YdiH PF15930.3 001290172.1_44826001_3 - 0.29 11.2 2.2 1.1 9.3 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function LRR_8 PF13855.4 001329083.1_37927001_2 - 1.2e-57 191.3 63.1 6.7e-12 44.9 1.9 9.6 7 2 3 10 10 10 9 Leucine rich repeat TIR PF01582.18 001329083.1_37927001_2 - 1.4e-32 112.8 2.7 2.2e-32 112.1 2.7 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001329083.1_37927001_2 - 4e-28 96.8 49.5 1.5e-05 25.1 0.5 11.2 9 1 2 11 11 11 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001329083.1_37927001_2 - 2e-12 47.0 0.3 3.8e-06 26.7 0.1 4.1 3 2 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001329083.1_37927001_2 - 9.8e-08 31.6 17.4 0.022 14.1 0.9 4.9 3 2 2 5 5 5 5 Leucine-rich repeat TIR_2 PF13676.4 001329083.1_37927001_2 - 1.5e-05 25.1 0.1 3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001329083.1_37927001_2 - 0.0001 22.1 46.4 5.5 7.7 0.0 14.6 11 2 1 12 12 12 1 Leucine Rich Repeat LRR_6 PF13516.4 001329083.1_37927001_2 - 0.0056 16.5 37.4 21 5.4 1.1 12.9 14 0 0 14 14 14 0 Leucine Rich repeat FNIP PF05725.10 001329083.1_37927001_2 - 0.0064 16.5 0.0 3.4 7.8 0.0 4.4 2 2 0 2 2 2 1 FNIP Repeat LRRCT PF01463.22 001329083.1_37927001_2 - 0.016 15.6 0.4 20 5.9 0.0 4.1 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain Orn_Arg_deC_N PF02784.14 001293732.1_36224001_3 - 3.9e-69 232.7 0.0 4.9e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293732.1_36224001_3 - 3.5e-19 68.8 0.0 6.4e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293732.1_36224001_3 - 0.00018 20.9 0.0 0.00088 18.6 0.0 1.9 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel MRP PF09387.8 001135353.1_43529001_2 - 3.6e-93 310.9 0.5 6.3e-93 310.1 0.5 1.4 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Sad1_UNC PF07738.11 001135353.1_43529001_2 - 2.6e-46 156.9 0.0 5.6e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CENP-F_N PF10481.7 001135353.1_43529001_2 - 0.0078 15.8 1.6 0.015 14.8 1.6 1.4 1 0 0 1 1 1 1 Cenp-F N-terminal domain Mnd1 PF03962.13 001135353.1_43529001_2 - 0.013 15.3 1.9 0.024 14.4 1.9 1.3 1 0 0 1 1 1 0 Mnd1 family Trimer_CC PF08954.9 001135353.1_43529001_2 - 0.015 14.7 0.2 0.015 14.7 0.2 2.4 3 0 0 3 3 3 0 Trimerisation motif Prefoldin_2 PF01920.18 001135353.1_43529001_2 - 0.025 14.4 3.4 0.14 12.0 0.6 2.8 2 1 1 3 3 3 0 Prefoldin subunit ZapB PF06005.10 001135353.1_43529001_2 - 0.076 13.3 0.7 18 5.8 2.6 2.5 1 1 1 2 2 2 0 Cell division protein ZapB JIP_LZII PF16471.3 001135353.1_43529001_2 - 0.086 12.9 2.7 0.17 11.9 1.1 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II GrpE PF01025.17 001135353.1_43529001_2 - 0.097 12.2 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 GrpE CCDC144C PF14915.4 001135353.1_43529001_2 - 0.32 9.9 6.6 2.3 7.1 5.2 2.2 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region MCC-bdg_PDZ PF10506.7 001131104.1_43529001_2 - 2.3e-42 142.7 21.2 7.3e-28 96.2 7.4 6.4 6 1 1 7 7 7 2 PDZ domain of MCC-2 bdg protein for Usher syndrome Mod_r PF07200.11 001131104.1_43529001_2 - 0.00038 20.5 0.2 0.00038 20.5 0.2 6.0 5 1 0 5 5 5 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.9 001131104.1_43529001_2 - 0.0028 16.5 3.4 0.0028 16.5 3.4 5.5 4 1 1 5 5 5 2 Spc7 kinetochore protein ERM PF00769.17 001131104.1_43529001_2 - 0.098 12.3 77.3 0.11 12.2 14.6 4.4 4 0 0 4 4 4 0 Ezrin/radixin/moesin family GAS PF13851.4 001131104.1_43529001_2 - 1.9 7.7 67.9 0.28 10.4 1.4 6.4 5 1 1 6 6 6 0 Growth-arrest specific micro-tubule binding APG6 PF04111.10 001131104.1_43529001_2 - 3.4 6.9 72.7 0.08 12.2 1.6 5.4 5 0 0 5 5 5 0 Autophagy protein Apg6 T2SSF PF00482.21 001131104.1_43529001_2 - 7.5 6.4 6.7 1.9 8.3 1.1 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Translin PF01997.14 038093.1_43526120_2 - 4.1e-53 180.3 0.1 5.5e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 Translin family ODR4-like PF14778.4 024161.1_43525120_2 - 2.8e-52 177.7 0.2 2.5e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 Olfactory receptor 4-like ODR4-like PF14778.4 024161.1_43525120_3 - 2.4e-56 191.1 2.1 3.4e-56 190.6 2.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like Asp_protease_2 PF13650.4 001302513.1_36226001_1 - 2.5e-05 24.7 0.1 7.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.9 001302513.1_36226001_1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001302513.1_36226001_1 - 0.0051 17.2 0.0 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001302513.1_36226001_2 - 2.7e-15 56.3 0.8 3.7e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001302513.1_36226001_2 - 2.9e-14 52.8 0.0 6.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) RP-C_C PF11800.6 001302513.1_36226001_2 - 0.44 10.4 8.8 0.85 9.5 8.8 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.15 001302513.1_36226001_2 - 4.4 5.8 5.0 5.5 5.5 5.0 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.8 001302513.1_36226001_2 - 8.1 4.9 7.1 11 4.4 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Asp_protease_2 PF13650.4 001291351.1_12129001_2 - 0.00028 21.4 0.0 0.00045 20.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291351.1_12129001_2 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease PRIMA1 PF16101.3 001291351.1_12129001_2 - 0.014 15.3 0.8 0.014 15.3 0.8 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 gag-asp_proteas PF13975.4 001291351.1_12129001_2 - 0.029 14.8 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291351.1_12129001_3 - 2.2e-15 56.4 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291351.1_12129001_3 - 2.5e-14 53.2 3.2 7.7e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein KASH_CCD PF14662.4 001291351.1_12129001_3 - 0.00014 21.6 5.5 0.00024 20.9 5.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001291351.1_12129001_3 - 0.00029 20.8 0.1 0.00052 20.0 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion zf-CCHC_5 PF14787.4 001291351.1_12129001_3 - 0.0029 17.1 0.2 0.0084 15.7 0.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger IncA PF04156.12 001291351.1_12129001_3 - 0.013 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 IncA protein Uso1_p115_C PF04871.11 001291351.1_12129001_3 - 0.023 14.9 3.9 0.037 14.3 3.9 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.10 001291351.1_12129001_3 - 0.031 14.6 7.9 0.085 13.2 7.9 1.7 1 0 0 1 1 1 0 Cell division protein ZapB CCDC106 PF15794.3 001291351.1_12129001_3 - 0.05 13.2 1.0 0.1 12.2 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TolA_bind_tri PF16331.3 001291351.1_12129001_3 - 0.055 13.4 3.3 0.11 12.5 3.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3450 PF11932.6 001291351.1_12129001_3 - 0.14 11.3 5.9 0.22 10.6 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ERM PF00769.17 001291351.1_12129001_3 - 0.16 11.7 5.9 0.27 10.9 5.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.10 001291351.1_12129001_3 - 0.16 11.8 1.4 0.33 10.8 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.9 001291351.1_12129001_3 - 0.17 10.6 4.5 0.31 9.7 4.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291351.1_12129001_3 - 0.28 11.7 3.4 0.7 10.4 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) SlyX PF04102.10 001291351.1_12129001_3 - 0.38 11.3 4.6 0.14 12.6 1.5 1.9 2 0 0 2 2 1 0 SlyX TMF_DNA_bd PF12329.6 001291351.1_12129001_3 - 0.5 10.3 8.5 0.95 9.4 8.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.13 001291351.1_12129001_3 - 0.57 9.9 5.1 1.4 8.6 5.1 1.6 1 0 0 1 1 1 0 Septum formation initiator CENP-H PF05837.10 001291351.1_12129001_3 - 0.58 10.4 4.4 1.2 9.4 4.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_1 PF00170.19 001291351.1_12129001_3 - 1.2 9.2 8.0 3.1 7.8 8.0 1.7 1 0 0 1 1 1 0 bZIP transcription factor SHE3 PF17078.3 001291351.1_12129001_3 - 1.7 8.2 8.1 0.59 9.7 5.3 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 GIT_CC PF16559.3 001291351.1_12129001_3 - 2.4 8.1 7.6 6.9 6.7 7.6 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.16 001291351.1_12129001_3 - 7.6 6.7 6.8 7.4 6.7 2.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper IL8 PF00048.18 001310178.1_33421001_1 - 9.2e-17 60.8 0.8 9.2e-17 60.8 0.8 1.4 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like Hormone_1 PF00103.18 001290352.1_08022001_3 - 4.8e-47 160.4 0.9 5.5e-47 160.2 0.9 1.0 1 0 0 1 1 1 1 Somatotropin hormone family HipA_C PF07804.10 001290352.1_08022001_3 - 0.068 13.1 0.1 4.7 7.2 0.0 2.2 2 0 0 2 2 2 0 HipA-like C-terminal domain CLTH PF10607.7 001290352.1_08022001_3 - 0.078 12.7 1.4 0.14 11.9 1.4 1.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Trp_leader1 PF08055.9 001290352.1_08022001_3 - 0.11 12.1 2.1 0.23 11.1 2.1 1.5 1 0 0 1 1 1 0 Tryptophan leader peptide Ribosomal_60s PF00428.17 001204128.1_08029001_2 - 4 7.9 10.1 9.5 6.7 10.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein AKAP2_C PF15304.4 001204128.1_08029001_3 - 8.3e-19 67.9 4.4 8.3e-19 67.9 4.4 2.7 2 1 0 2 2 2 1 A-kinase anchor protein 2 C-terminus SUIM_assoc PF16619.3 001204128.1_08029001_3 - 1.9 8.5 12.0 0.25 11.4 6.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ANAPC15 PF15243.4 001282058.1_08022001_2 - 7.3e-39 131.9 15.2 7.3e-39 131.9 15.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 DUF4746 PF15928.3 001282058.1_08022001_2 - 0.095 12.0 6.8 0.13 11.5 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.10 001282058.1_08022001_2 - 1.5 6.8 18.8 1.8 6.5 18.8 1.0 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.6 001282058.1_08022001_2 - 1.6 7.7 15.7 2 7.3 15.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2457 PF10446.7 001282058.1_08022001_2 - 3.9 6.4 28.8 5.3 5.9 28.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.12 001282058.1_08022001_2 - 7.2 4.6 16.7 9.3 4.3 16.7 1.0 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.8 001282058.1_08022001_2 - 9.4 4.5 14.4 12 4.1 14.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein MFS_1 PF07690.14 001168942.1_40423001_1 - 6.7e-61 206.0 32.8 1.2e-59 201.9 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cas1_AcylT PF07779.10 001168942.1_40423001_1 - 0.0026 16.6 1.9 0.0052 15.6 1.9 1.4 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p CoA_transf_3 PF02515.15 001112633.1_40423001_1 - 2.3e-82 276.9 0.0 4.3e-82 276.0 0.0 1.4 1 1 0 1 1 1 1 CoA-transferase family III IL8 PF00048.18 001173538.1_40421001_1 - 5.6e-23 80.7 2.9 6.9e-23 80.4 2.9 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF4725 PF15854.3 001173538.1_40421001_1 - 0.0078 16.3 0.2 0.0096 16.0 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4725) zf-H2C2_2 PF13465.4 001270904.1_08029001_2 - 1.4e-87 284.3 92.2 1.1e-08 35.0 1.9 15.9 15 0 0 15 15 15 13 Zinc-finger double domain zf-C2H2 PF00096.24 001270904.1_08029001_2 - 8.2e-52 170.8 102.6 4.3e-06 26.8 1.6 14.4 13 0 0 13 13 13 13 Zinc finger, C2H2 type KRAB PF01352.25 001270904.1_08029001_2 - 1.8e-22 78.6 0.5 3.4e-22 77.7 0.5 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001270904.1_08029001_2 - 1e-19 69.3 104.4 0.0091 16.6 0.5 15.3 14 0 0 14 14 14 11 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001270904.1_08029001_2 - 1.3e-11 44.0 78.2 0.13 12.1 0.2 13.8 13 0 0 13 13 13 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001270904.1_08029001_2 - 1.9e-08 34.3 52.4 0.37 11.0 0.1 12.7 13 0 0 13 13 13 7 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001270904.1_08029001_2 - 4.3e-06 26.6 66.3 0.24 11.4 2.6 9.6 5 3 3 9 9 9 8 Zinc ribbon domain XPA_N PF01286.16 001270904.1_08029001_2 - 0.014 15.3 59.1 7 6.7 0.1 13.2 13 0 0 13 13 13 0 XPA protein N-terminal zf-H2C2_2 PF13465.4 001270917.1_08026001_3 - 3.4e-125 403.3 118.4 3e-09 36.8 2.4 17.4 18 0 0 18 18 18 16 Zinc-finger double domain zf-C2H2 PF00096.24 001270917.1_08026001_3 - 1.8e-76 248.4 108.2 1.4e-06 28.3 0.3 16.8 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270917.1_08026001_3 - 3.2e-42 139.4 107.6 0.013 16.2 0.2 16.9 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001270917.1_08026001_3 - 2.5e-27 94.1 98.8 0.0011 18.7 0.8 16.6 16 0 0 16 16 16 12 C2H2-type zinc finger KRAB PF01352.25 001270917.1_08026001_3 - 4.1e-27 93.5 0.2 8e-27 92.5 0.2 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 001270917.1_08026001_3 - 1.5e-20 72.8 66.9 0.025 14.8 0.1 15.3 16 0 0 16 16 15 10 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001270917.1_08026001_3 - 1.5e-14 53.7 92.3 0.015 15.3 1.9 11.0 6 3 3 10 10 10 9 Zinc ribbon domain XPA_N PF01286.16 001270917.1_08026001_3 - 2.4e-08 33.7 77.4 2.9 7.9 0.1 16.2 16 0 0 16 16 16 6 XPA protein N-terminal zf-trcl PF13451.4 001270917.1_08026001_3 - 3.8e-08 32.9 76.8 0.34 10.7 5.5 15.3 14 2 2 16 16 16 6 Probable zinc-ribbon domain C1_4 PF07975.10 001270917.1_08026001_3 - 1.8e-05 24.7 84.4 0.15 12.2 7.5 11.3 3 1 10 14 14 14 7 TFIIH C1-like domain BHD_1 PF10403.7 001270917.1_08026001_3 - 0.015 15.0 6.1 45 3.9 0.0 6.7 4 3 3 7 7 7 0 Rad4 beta-hairpin domain 1 zf-LYAR PF08790.9 001270917.1_08026001_3 - 0.044 13.6 0.1 0.044 13.6 0.1 12.5 16 0 0 16 16 16 0 LYAR-type C2HC zinc finger DUF3268 PF11672.6 001270917.1_08026001_3 - 4.1 7.6 64.1 1.1 9.4 1.6 8.7 4 1 5 11 11 11 0 zinc-finger-containing domain zf-H2C2_2 PF13465.4 001270907.1_08028001_2 - 1.7e-99 322.0 95.7 6.4e-09 35.7 3.2 14.7 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.24 001270907.1_08028001_2 - 8.6e-68 221.1 100.3 1.7e-06 28.0 2.9 13.8 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270907.1_08028001_2 - 1.8e-31 105.9 95.0 0.0071 17.0 0.2 14.1 13 0 0 13 13 13 12 C2H2-type zinc finger KRAB PF01352.25 001270907.1_08028001_2 - 8.3e-23 79.7 0.3 1.4e-22 78.9 0.3 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 001270907.1_08028001_2 - 2.7e-12 46.5 57.8 0.12 12.6 0.4 13.2 13 0 0 13 13 13 6 Zinc-finger double-stranded RNA-binding XPA_N PF01286.16 001270907.1_08028001_2 - 5.2e-11 42.3 56.8 3.4 7.7 0.1 13.7 13 0 0 13 13 13 6 XPA protein N-terminal zf-C2H2_6 PF13912.4 001270907.1_08028001_2 - 7.5e-11 41.6 85.9 0.084 12.7 0.8 14.3 13 1 0 13 13 13 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001270907.1_08028001_2 - 8.2e-09 35.3 73.8 0.021 14.8 1.9 9.7 2 2 9 12 12 12 8 Zinc ribbon domain zf-C2H2_11 PF16622.3 001270907.1_08028001_2 - 0.0012 18.4 71.2 0.41 10.3 0.5 12.8 13 0 0 13 13 13 7 zinc-finger C2H2-type zinc_ribbon_15 PF17032.3 001270907.1_08028001_2 - 0.0025 18.4 48.5 1.6 9.4 1.0 7.1 1 1 5 6 6 6 3 zinc-ribbon family BHD_1 PF10403.7 001270907.1_08028001_2 - 0.004 16.8 2.0 30 4.4 0.0 4.7 3 1 0 3 3 3 0 Rad4 beta-hairpin domain 1 zf-LYAR PF08790.9 001270907.1_08028001_2 - 0.066 13.0 59.6 2.5 7.9 0.1 12.5 13 0 0 13 13 13 0 LYAR-type C2HC zinc finger C1_4 PF07975.10 001270907.1_08028001_2 - 0.33 11.1 54.0 0.12 12.6 1.4 7.7 5 3 3 8 8 8 0 TFIIH C1-like domain Raffinose_syn PF05691.10 001270907.1_08028001_2 - 3.4 5.2 6.0 23 2.4 0.1 3.6 2 1 3 5 5 5 0 Raffinose synthase or seed imbibition protein Sip1 LRR_8 PF13855.4 001285555.1_09023001_3 - 7.9e-42 140.7 20.5 5.6e-16 57.9 2.8 4.4 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.5 001285555.1_09023001_3 - 3.4e-23 81.1 22.2 2e-05 24.7 2.2 5.8 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001285555.1_09023001_3 - 6.6e-12 45.4 0.8 6.7e-05 22.7 0.2 3.1 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001285555.1_09023001_3 - 3e-11 43.0 6.5 1.3e-05 24.7 3.1 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.16 001285555.1_09023001_3 - 2.9e-09 36.2 5.4 2.9e-09 36.2 5.4 2.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.31 001285555.1_09023001_3 - 8.8e-05 22.3 11.1 14 6.5 0.1 7.2 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.4 001285555.1_09023001_3 - 0.0021 17.8 17.3 0.34 11.0 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich repeat STAR_dimer PF16544.3 001285555.1_09023001_3 - 0.079 12.4 0.2 0.18 11.2 0.2 1.6 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein Glyco_hydro_38 PF01074.20 001289106.1_09028001_1 - 2.6e-109 364.9 1.5 3.9e-109 364.3 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.11 001289106.1_09028001_1 - 5.4e-86 289.3 0.0 7.4e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.9 001289106.1_09028001_1 - 1.1e-25 89.7 0.6 2.6e-25 88.4 0.6 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.13 001289106.1_09028001_1 - 0.00018 20.6 0.1 0.00038 19.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Pkinase PF00069.23 001285608.1_09023001_1 - 8.8e-79 264.4 0.0 1e-78 264.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001285608.1_09023001_1 - 2.2e-35 122.1 0.0 3.3e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001285608.1_09023001_1 - 0.0034 16.6 0.0 0.1 11.8 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.21 001285608.1_09023001_1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Lipocalin PF00061.21 001285623.1_09021001_1 - 5.9e-28 97.7 1.0 6.5e-28 97.6 1.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001285623.1_09021001_1 - 5.6e-07 29.4 1.2 7.1e-07 29.1 1.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Asp PF00026.21 001285722.1_09023001_1 - 1.4e-104 349.8 0.0 1.6e-104 349.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285722.1_09023001_1 - 6e-17 62.3 3.4 3.2e-09 37.2 0.1 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.4 001285722.1_09023001_1 - 7e-05 23.3 0.2 2.5 8.7 0.1 3.8 3 1 0 3 3 3 2 Aspartyl protease A1_Propeptide PF07966.10 001285722.1_09023001_1 - 0.00034 20.3 0.1 0.00059 19.5 0.1 1.4 1 0 0 1 1 1 1 A1 Propeptide OTCace PF00185.22 001285729.1_09023001_3 - 3.9e-51 173.1 0.0 5.5e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.19 001285729.1_09023001_3 - 1.6e-41 141.5 0.0 2.6e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_transf_7N PF13733.4 001285775.1_09024001_2 - 1.5e-59 199.3 0.1 2.1e-59 198.9 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.12 001285775.1_09024001_2 - 1.9e-29 101.0 0.1 3.5e-29 100.1 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.7 001285775.1_09024001_2 - 0.0033 16.8 0.0 0.0084 15.5 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Homeobox PF00046.27 001314271.1_09023001_2 - 2.6e-18 65.4 5.5 4.6e-18 64.7 5.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.6 001314271.1_09023001_2 - 0.033 13.5 2.5 0.1 12.0 0.6 2.5 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez TFIIF_alpha PF05793.10 001314271.1_09023001_2 - 0.14 10.6 2.5 0.18 10.2 2.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GLTT PF01744.18 001314271.1_09023001_3 - 0.43 10.3 3.1 0.74 9.5 2.1 1.9 1 1 0 1 1 1 0 GLTT repeat (6 copies) SRF-TF PF00319.16 001314200.1_09024001_3 - 1.6e-24 84.9 0.4 2.6e-24 84.3 0.4 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.6 001314200.1_09024001_3 - 5.7e-20 71.0 0.7 5.7e-20 71.0 0.7 3.1 2 1 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat DUF2360 PF10152.7 001314200.1_09024001_3 - 7.4 6.8 8.2 11 6.2 7.1 1.9 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Asp_protease_2 PF13650.4 001291087.1_46729001_2 - 0.00072 20.1 0.0 0.0012 19.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291087.1_46729001_2 - 0.015 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291087.1_46729001_2 - 0.048 14.1 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291087.1_46729001_3 - 4e-15 55.8 2.1 1.7e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291087.1_46729001_3 - 4.8e-15 55.3 0.0 8.2e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291087.1_46729001_3 - 0.00018 21.5 0.1 0.0003 20.8 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291087.1_46729001_3 - 0.002 17.9 5.0 0.0033 17.2 5.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291087.1_46729001_3 - 0.0028 17.2 0.2 0.0065 16.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291087.1_46729001_3 - 0.0044 16.8 0.5 0.0076 16.0 0.5 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF1664 PF07889.10 001291087.1_46729001_3 - 0.2 11.5 1.0 0.4 10.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.9 001291087.1_46729001_3 - 0.22 10.2 3.6 0.39 9.4 3.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.10 001291087.1_46729001_3 - 0.24 11.7 4.9 0.48 10.7 4.9 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001291087.1_46729001_3 - 0.28 11.7 3.9 0.69 10.4 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291087.1_46729001_3 - 0.36 11.2 9.9 0.83 10.0 9.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB TolA_bind_tri PF16331.3 001291087.1_46729001_3 - 0.45 10.5 4.4 0.85 9.6 4.4 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation SlyX PF04102.10 001291087.1_46729001_3 - 0.53 10.8 2.8 1.3 9.5 2.8 1.7 1 0 0 1 1 1 0 SlyX IncA PF04156.12 001291087.1_46729001_3 - 0.63 9.7 4.5 1.3 8.7 4.5 1.4 1 0 0 1 1 1 0 IncA protein bZIP_1 PF00170.19 001291087.1_46729001_3 - 0.77 9.8 6.5 2 8.5 6.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor TMF_DNA_bd PF12329.6 001291087.1_46729001_3 - 0.92 9.4 6.5 1.9 8.4 6.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.13 001291087.1_46729001_3 - 2.8 7.6 6.8 6.5 6.5 6.8 1.5 1 0 0 1 1 1 0 Septum formation initiator CCDC106 PF15794.3 001291087.1_46729001_3 - 4.5 6.8 6.9 0.5 9.9 2.5 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 GIT_CC PF16559.3 001291087.1_46729001_3 - 4.7 7.2 7.9 13 5.8 8.0 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SHE3 PF17078.3 001291087.1_46729001_3 - 6.6 6.2 10.8 1.7 8.1 7.8 1.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Orn_Arg_deC_N PF02784.14 001293720.1_46725001_1 - 6.4e-70 235.3 0.0 8e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293720.1_46725001_1 - 6.9e-20 71.1 0.0 1.1e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293720.1_46725001_1 - 0.00041 19.7 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel APOBEC_N PF08210.9 001345916.1_30124001_3 - 1.2e-87 292.3 4.9 1.8e-44 151.6 0.2 2.1 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001345916.1_30124001_3 - 4e-62 206.0 0.0 1.2e-29 101.9 0.0 2.7 2 0 0 2 2 2 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001345916.1_30124001_3 - 0.0019 17.9 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region DUF3024 PF11225.6 001345916.1_30124001_3 - 0.03 14.4 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) Toxin-deaminase PF14424.4 001345916.1_30124001_3 - 0.056 13.4 0.1 9.4 6.2 0.1 2.3 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases Pox_A3L PF05288.9 001345916.1_30124001_3 - 0.076 12.9 0.2 4.8 7.1 0.0 2.8 2 1 0 2 2 2 0 Poxvirus A3L Protein NODP PF07684.10 001345916.1_30124001_3 - 0.54 10.3 2.1 1.4 9.0 0.2 2.1 2 0 0 2 2 2 0 NOTCH protein APOBEC_N PF08210.9 001345905.1_46224001_3 - 1.2e-86 289.0 5.8 4.4e-45 153.6 0.0 2.1 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001345905.1_46224001_3 - 4.2e-60 199.5 0.1 8.8e-29 99.2 0.0 3.1 3 0 0 3 3 3 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001345905.1_46224001_3 - 0.001 18.8 0.1 1.7 8.4 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.4 001345905.1_46224001_3 - 0.0064 16.5 0.1 0.78 9.7 0.1 2.2 2 0 0 2 2 2 1 The BURPS668_1122 family of deaminases Pox_A3L PF05288.9 001345905.1_46224001_3 - 0.061 13.2 1.8 3.6 7.5 0.0 3.5 3 1 0 3 3 3 0 Poxvirus A3L Protein NODP PF07684.10 001345905.1_46224001_3 - 0.32 11.0 3.2 0.63 10.1 0.3 2.2 2 0 0 2 2 2 0 NOTCH protein APOBEC_N PF08210.9 001345963.1_46223001_2 - 1.1e-57 194.7 4.7 1.4e-57 194.4 4.7 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001345963.1_46223001_2 - 1.1e-32 111.7 0.0 2.2e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001345963.1_46223001_2 - 0.0047 16.6 0.1 0.0073 16.0 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Hairy_orange PF07527.11 001345963.1_46223001_2 - 0.044 13.9 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Hairy Orange Toxin-deaminase PF14424.4 001345963.1_46223001_2 - 0.1 12.6 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases APOBEC_N PF08210.9 001345971.1_35726001_2 - 8.8e-58 195.0 5.1 1.2e-57 194.6 5.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001345971.1_35726001_2 - 1.9e-32 110.9 0.2 3.1e-32 110.2 0.2 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001345971.1_35726001_2 - 0.019 14.7 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.9 001345972.1_35724001_3 - 3.8e-98 326.4 5.5 9.4e-49 165.6 2.7 2.1 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001345972.1_35724001_3 - 1.6e-60 200.8 1.6 1.7e-29 101.5 0.0 2.8 2 1 0 2 2 2 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001345972.1_35724001_3 - 0.04 13.7 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.9 001345954.1_11723001_2 - 1.2e-100 334.6 6.7 3.3e-51 173.6 1.9 2.0 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001345954.1_11723001_2 - 3.2e-62 206.3 0.3 3.4e-30 103.7 0.0 2.4 2 0 0 2 2 2 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001345954.1_11723001_2 - 0.0024 17.6 0.0 0.036 13.8 0.0 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.4 001345954.1_11723001_2 - 0.063 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases DUF2749 PF10907.6 001280287.1_39726001_1 - 0.76 9.9 3.1 5.4 7.1 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) HMG_box PF00505.17 001280287.1_39726001_2 - 5.4e-23 81.1 2.4 9e-23 80.4 2.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001280287.1_39726001_2 - 1.6e-10 41.3 0.8 3.1e-10 40.4 0.8 1.4 1 0 0 1 1 1 1 HMG-box domain 7tm_1 PF00001.19 001242410.1_39727001_2 - 2.5e-37 128.4 7.7 4e-37 127.8 7.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001242410.1_39727001_2 - 6.2e-06 26.0 1.5 1.2e-05 25.1 1.5 1.4 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001242410.1_39727001_2 - 0.00052 19.3 3.0 0.00052 19.3 3.0 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.7 001242410.1_39727001_2 - 0.00098 18.4 1.9 0.0016 17.7 1.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv PgaD PF13994.4 001242410.1_39727001_2 - 0.25 11.2 2.3 0.9 9.4 1.3 2.2 2 0 0 2 2 2 0 PgaD-like protein DUF3429 PF11911.6 001242410.1_39727001_2 - 1.9 8.7 6.8 0.93 9.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) DP PF08781.8 001280410.1_39724001_3 - 3.4e-61 205.0 2.9 6.3e-61 204.2 2.9 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.18 001280410.1_39724001_3 - 2.2e-26 91.5 0.3 4.5e-26 90.5 0.3 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain FliD_C PF07195.10 001280410.1_39724001_3 - 0.25 10.6 4.7 0.33 10.2 2.0 2.0 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus PRAS PF15798.3 001246387.1_39725001_2 - 9.7e-49 164.9 0.7 1.7e-48 164.1 0.7 1.4 1 0 0 1 1 1 1 Proline-rich AKT1 substrate 1 FWWh PF14922.4 001246614.1_39725001_3 - 2.1e-54 183.4 0.3 4.3e-54 182.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function DegS PF05384.9 001246614.1_39725001_3 - 0.013 14.9 0.1 0.032 13.6 0.1 1.7 1 0 0 1 1 1 0 Sensor protein DegS DUF4897 PF16238.3 001246614.1_39725001_3 - 0.081 12.6 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) DUF2655 PF10848.6 001134339.1_39724001_1 - 0.67 10.2 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2655) MHC_II_alpha PF00993.18 001134339.1_39724001_2 - 2.1e-34 116.9 0.2 3e-34 116.4 0.2 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001134339.1_39724001_2 - 7.1e-29 98.8 0.1 1.5e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 C1-set C-terminal domain C1-set PF07654.13 001134339.1_39724001_2 - 5e-22 78.0 0.0 1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Marek_A PF02124.13 001134339.1_39724001_2 - 0.00088 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Marek's disease glycoprotein A Ig_3 PF13927.4 001134339.1_39724001_2 - 0.0045 17.4 0.0 0.0083 16.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Arm_2 PF04826.11 001279976.1_39724001_1 - 1.7e-112 374.9 5.0 2.1e-112 374.6 5.0 1.1 1 0 0 1 1 1 1 Armadillo-like Atx10homo_assoc PF09759.7 001279976.1_39724001_1 - 0.0017 18.3 0.5 0.12 12.3 0.2 3.4 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.21 001279976.1_39724001_1 - 0.048 13.6 1.4 1.3 9.0 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PUL PF08324.9 001279976.1_39724001_1 - 0.2 10.8 5.0 0.26 10.4 4.0 1.6 1 1 1 2 2 2 0 PUL domain Choline_kinase PF01633.18 001280076.1_39724001_2 - 1.9e-76 256.3 0.1 2.7e-76 255.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.21 001280076.1_39724001_2 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.18 001280076.1_39724001_2 - 1.2e-05 24.7 0.0 2.4e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.12 001280076.1_39724001_2 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SYCE1 PF15233.4 001280134.1_39723001_2 - 4.7e-67 224.6 22.8 4.7e-67 224.6 22.8 4.0 4 0 0 4 4 4 1 Synaptonemal complex central element protein 1 CENP-Q PF13094.4 001280134.1_39723001_2 - 0.01 15.9 4.6 0.01 15.9 4.6 4.1 4 1 0 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.10 001280134.1_39723001_2 - 0.065 12.5 0.8 0.085 12.1 0.4 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF745 PF05335.11 001280134.1_39723001_2 - 1.1 8.9 30.9 0.057 13.0 9.3 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF745) P16-Arc PF04699.12 001246501.1_39724001_3 - 1.9e-59 200.3 0.0 2.6e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UTP15_C PF09384.8 001246501.1_39724001_3 - 0.054 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal Utp12 PF04003.10 001246501.1_39724001_3 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family SSXT PF05030.10 001246581.1_39724001_3 - 3.9e-29 99.9 4.3 6.4e-29 99.3 4.3 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Methyltransf_23 PF13489.4 001243095.1_39725001_3 - 0.0019 18.0 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001243095.1_39725001_3 - 0.024 15.2 0.0 0.048 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Metallothio PF00131.18 125723.1_39721120_2 - 7.5e-13 48.3 33.3 1.1e-12 47.8 33.3 1.1 1 0 0 1 1 1 1 Metallothionein LINES_C PF14695.4 125723.1_39721120_2 - 0.067 12.5 0.1 0.067 12.5 0.1 2.2 2 1 1 3 3 3 0 Lines C-terminus VESA1_N PF12785.5 125723.1_39721120_2 - 9.6 4.9 22.4 11 4.7 22.4 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 ARA70 PF12489.6 073402.2_39726120_1 - 6.5e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear coactivator ARA70 PF12489.6 073402.2_39726120_2 - 0.078 13.0 3.5 3.4 7.7 0.2 3.3 2 1 1 3 3 3 0 Nuclear coactivator IncA PF04156.12 132631.1_39721120_1 - 0.031 14.0 6.4 0.033 13.8 6.4 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.10 132631.1_39721120_1 - 0.094 12.0 6.4 0.11 11.8 6.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.11 132631.1_39721120_1 - 0.53 10.8 4.8 0.74 10.3 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CENP-H PF05837.10 132631.1_39721120_1 - 0.8 10.0 9.6 1.1 9.6 9.6 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) NuA4 PF09340.8 132631.1_39721120_1 - 0.97 9.2 2.7 2.2 8.1 0.6 2.2 1 1 1 2 2 2 0 Histone acetyltransferase subunit NuA4 OmpH PF03938.12 132631.1_39721120_1 - 1.7 8.5 11.2 2.6 7.9 11.2 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MHC_I PF00129.16 024036.1_39723120_3 - 5e-93 309.5 1.5 7.2e-93 309.0 1.5 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 024036.1_39723120_3 - 1.5e-17 63.7 0.0 4.7e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 024036.1_39723120_3 - 1.2e-13 50.6 7.7 2e-13 49.8 7.7 1.4 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 024036.1_39723120_3 - 2.5e-06 27.9 0.9 0.042 14.3 0.0 3.2 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 024036.1_39723120_3 - 0.00052 19.9 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 024036.1_39723120_3 - 0.0041 17.1 0.1 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain EphA2_TM PF14575.4 024036.1_39723120_3 - 0.12 13.1 0.1 0.36 11.5 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Defensin_beta_2 PF13841.4 036558.1_39721120_1 - 0.00038 20.7 2.3 0.00038 20.7 2.3 1.5 2 0 0 2 2 2 1 Beta defensin PIP5K PF01504.16 024414.2_39728120_3 - 3.5e-89 298.6 0.0 6.7e-89 297.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase VWA_2 PF13519.4 024414.2_39728120_3 - 4.6e-20 72.2 0.0 1.2e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.12 024414.2_39728120_3 - 2.8e-05 23.9 0.1 4.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like Glyco_transf_6 PF03414.11 132137.2_39727120_2 - 1.5e-50 171.7 5.1 1.8e-50 171.4 2.0 1.9 1 1 1 2 2 2 2 Glycosyltransferase family 6 Glyco_transf_6 PF03414.11 132137.2_39727120_3 - 4.6e-40 137.2 0.2 6.5e-40 136.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 MHC_II_beta PF00969.17 036548.1_39722120_1 - 3e-25 88.0 0.2 5e-25 87.3 0.2 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 036548.1_39722120_2 - 6.3e-26 90.5 0.1 1.3e-25 89.5 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.23 036548.1_39722120_2 - 0.00021 21.3 0.1 0.00042 20.3 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain EF-hand_1 PF00036.30 001199977.1_43529001_2 - 0.007 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.4 001199977.1_43529001_2 - 0.026 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.4 001199977.1_43529001_2 - 0.04 14.3 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair RskA PF10099.7 001199977.1_43529001_2 - 7 6.8 15.5 0.48 10.6 9.4 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA CARD_2 PF16739.3 001290158.1_44827001_2 - 5.8e-53 176.7 0.8 2e-25 88.5 0.0 2.7 2 0 0 2 2 2 2 Caspase recruitment domain RIG-I_C-RD PF11648.6 001290158.1_44827001_2 - 3.1e-35 120.9 4.4 8.6e-35 119.4 4.4 1.8 1 0 0 1 1 1 1 C-terminal domain of RIG-I ResIII PF04851.13 001290158.1_44827001_2 - 1.3e-16 60.9 0.1 8.1e-16 58.4 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.29 001290158.1_44827001_2 - 4.7e-16 59.0 0.1 3e-15 56.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.27 001290158.1_44827001_2 - 3.2e-15 56.2 0.0 9.4e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.4 001290158.1_44827001_2 - 0.00013 22.1 0.1 0.0052 16.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain Latarcin PF10279.7 001290158.1_44827001_2 - 0.061 13.6 0.4 1.8 8.9 0.0 3.1 3 1 0 3 3 3 0 Latarcin precursor PTS_IIB PF02302.15 001290158.1_44827001_2 - 0.069 13.7 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit AAA_25 PF13481.4 001290158.1_44827001_2 - 0.13 11.7 0.0 0.65 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain CCDC85 PF10226.7 001290158.1_44827001_2 - 0.18 11.3 2.4 0.16 11.5 0.4 1.8 2 0 0 2 2 2 0 CCDC85 family DUF846 PF05832.10 001281943.1_13422001_3 - 3.9e-56 188.8 9.8 4.9e-56 188.5 9.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) HXXEE PF13787.4 001281943.1_13422001_3 - 0.23 12.1 7.4 0.81 10.3 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif DUF846 PF05832.10 001281970.1_27022001_2 - 9.8e-56 187.5 8.1 1.2e-55 187.2 8.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM192 PF14802.4 001281970.1_27022001_2 - 0.083 11.8 0.2 0.15 11.0 0.2 1.3 1 0 0 1 1 1 0 TMEM192 family DUF846 PF05832.10 001281947.1_10722001_1 - 1.6e-56 190.1 9.2 1.9e-56 189.8 9.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMC PF07810.11 001281947.1_10722001_1 - 0.02 15.3 0.1 0.02 15.3 0.1 1.7 2 0 0 2 2 2 0 TMC domain HXXEE PF13787.4 001281947.1_10722001_1 - 0.44 11.2 7.7 2.2 9.0 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif DUF846 PF05832.10 001281925.1_48822001_2 - 7.1e-56 188.0 9.8 8.7e-56 187.7 9.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMC PF07810.11 001281925.1_48822001_2 - 0.12 12.8 3.0 0.22 12.0 3.0 1.7 1 1 0 1 1 1 0 TMC domain HXXEE PF13787.4 001281925.1_48822001_2 - 3.5 8.3 8.8 4.7 7.9 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif DUF846 PF05832.10 001281962.1_36222001_1 - 5.4e-56 188.3 7.1 6.7e-56 188.0 7.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMC PF07810.11 001281962.1_36222001_1 - 0.026 15.0 0.8 0.026 15.0 0.8 1.8 2 0 0 2 2 2 0 TMC domain TMEM192 PF14802.4 001281962.1_36222001_1 - 0.042 12.8 0.2 0.07 12.1 0.2 1.3 1 0 0 1 1 1 0 TMEM192 family DUF846 PF05832.10 001281964.1_37424001_1 - 8.5e-56 187.7 9.1 2e-55 186.5 9.1 1.7 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF846 PF05832.10 001281949.1_36522001_1 - 4.6e-56 188.6 10.3 5.8e-56 188.2 10.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMC PF07810.11 001281949.1_36522001_1 - 0.082 13.3 3.2 0.16 12.4 3.2 1.7 1 1 0 1 1 1 0 TMC domain HXXEE PF13787.4 001281949.1_36522001_1 - 4.4 8.0 9.0 10 6.8 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif DUF846 PF05832.10 001281860.1_46724001_3 - 7.2e-55 184.7 9.9 1.4e-54 183.8 9.9 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Snf7 PF03357.19 001276456.1_45723001_2 - 2.6e-55 186.5 17.9 2.6e-55 186.5 17.9 1.4 2 0 0 2 2 2 1 Snf7 SYF2 PF08231.10 001276456.1_45723001_2 - 0.0017 18.6 9.0 0.0029 17.9 9.0 1.4 1 0 0 1 1 1 1 SYF2 splicing factor WD-3 PF09765.7 001276456.1_45723001_2 - 0.3 10.2 2.5 0.47 9.6 2.5 1.3 1 1 0 1 1 1 0 WD-repeat region DUF4407 PF14362.4 001276456.1_45723001_2 - 2.5 7.2 9.0 3.8 6.6 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) 7tm_4 PF13853.4 001000804.1_45722001_1 - 4.8e-48 164.2 26.8 6.5e-48 163.7 26.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000804.1_45722001_1 - 9.2e-22 77.4 24.4 1.8e-21 76.4 24.4 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000804.1_45722001_1 - 0.0055 16.0 26.1 0.0084 15.4 26.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ribosomal_S4e PF00900.18 131253.1_45723120_1 - 0.00038 20.2 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.3 131253.1_45723120_2 - 2.1e-25 88.0 0.1 3.2e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus Ribosomal_S4e PF00900.18 131253.1_45723120_2 - 0.0017 18.1 0.0 0.0059 16.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.10 131253.1_45723120_3 - 1.8e-13 50.2 0.2 3.9e-13 49.1 0.2 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain Ribosomal_S4e PF00900.18 131253.1_45723120_3 - 6.8e-12 45.0 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal family S4e S4 PF01479.23 131253.1_45723120_3 - 0.055 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 S4 domain TLV_coat PF00429.17 131094.1_45726120_2 - 2e-12 46.5 6.2 7.2e-08 31.4 0.1 2.8 3 0 0 3 3 3 2 ENV polyprotein (coat polyprotein) POT1PC PF16686.3 001319559.1_29527001_2 - 1.1e-40 138.9 0.0 6.8e-40 136.4 0.0 2.1 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.15 001319559.1_29527001_2 - 7.8e-36 122.9 0.1 2e-35 121.5 0.1 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.23 001319559.1_29527001_2 - 0.0056 16.5 1.3 28 4.6 0.0 4.0 3 1 1 4 4 4 2 OB-fold nucleic acid binding domain Zn_Tnp_IS1 PF03811.11 001319559.1_29527001_2 - 0.031 13.9 0.0 0.088 12.4 0.0 1.8 1 0 0 1 1 1 0 InsA N-terminal domain Pyridoxal_deC PF00282.17 001319425.1_29525001_2 - 6.8e-135 449.4 0.0 8.3e-135 449.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.17 001319425.1_29525001_2 - 0.00034 19.6 0.0 0.0012 17.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.19 001319425.1_29525001_2 - 0.002 17.4 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Proteasome PF00227.24 001285064.1_29524001_2 - 1.5e-53 181.0 0.2 2e-53 180.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001285064.1_29524001_2 - 1e-14 53.7 0.1 1.8e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Filament PF00038.19 001279670.1_24224001_1 - 1.1e-99 333.8 28.1 1.3e-99 333.6 28.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Jnk-SapK_ap_N PF09744.7 001279670.1_24224001_1 - 0.014 15.5 26.1 0.039 14.0 7.2 3.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF3373 PF11853.6 001279670.1_24224001_1 - 0.65 8.5 6.1 8.5 4.9 6.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) DUF5082 PF16888.3 001279670.1_24224001_1 - 1.5 9.1 14.4 0.057 13.6 4.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF1664 PF07889.10 001279670.1_24224001_1 - 2.1 8.2 10.0 6.8 6.6 0.3 3.5 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) IMD PF08397.9 001279670.1_24224001_1 - 4.2 6.6 12.2 0.12 11.6 3.8 2.3 1 1 0 2 2 2 0 IRSp53/MIM homology domain TPR_MLP1_2 PF07926.10 001279670.1_24224001_1 - 4.2 7.3 29.4 0.16 11.9 4.0 3.8 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Lzipper-MIP1 PF14389.4 001279670.1_24224001_1 - 8.5 6.6 16.3 0.1 12.7 3.5 3.7 3 2 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 BRCT_assoc PF12820.5 001308668.1_35729001_1 - 3.7e-81 270.6 1.5 3.7e-81 270.6 1.5 3.5 4 0 0 4 4 4 1 Serine-rich domain associated with BRCT BRCT PF00533.24 001308668.1_35729001_1 - 1.1e-18 67.3 0.0 6.1e-09 36.0 0.0 3.1 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-C3HC4 PF00097.23 001308668.1_35729001_1 - 1.3e-09 37.7 10.7 4.6e-09 35.9 10.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001308668.1_35729001_1 - 4.8e-09 35.8 11.1 1.3e-08 34.4 11.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.4 001308668.1_35729001_1 - 9.3e-08 32.0 10.7 3.3e-07 30.2 10.7 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.4 001308668.1_35729001_1 - 3.6e-07 29.8 7.6 8.7e-07 28.6 7.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001308668.1_35729001_1 - 6.5e-07 29.4 8.6 2.8e-06 27.4 8.6 2.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.4 001308668.1_35729001_1 - 7.5e-07 28.9 9.0 2.4e-06 27.3 9.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001308668.1_35729001_1 - 1.1e-05 25.1 8.7 3.5e-05 23.5 8.7 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.6 001308668.1_35729001_1 - 0.0002 21.0 7.4 0.00057 19.5 7.4 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.4 001308668.1_35729001_1 - 0.00033 20.3 2.1 0.00077 19.2 2.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein BRCT_2 PF16589.3 001308668.1_35729001_1 - 0.00046 20.4 0.0 0.33 11.3 0.0 2.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain zf-ANAPC11 PF12861.5 001308668.1_35729001_1 - 0.002 18.0 1.6 0.0046 16.8 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.4 001308668.1_35729001_1 - 0.0023 17.6 9.2 0.0048 16.6 7.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.3 001308668.1_35729001_1 - 0.0035 17.3 7.0 0.012 15.6 7.0 1.9 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.5 001308668.1_35729001_1 - 0.0098 16.0 4.7 0.039 14.1 4.7 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.4 001308668.1_35729001_1 - 0.68 9.6 7.1 1.9 8.2 7.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain JmjC PF02373.20 001291400.1_28828001_1 - 2.2e-08 34.4 0.0 6.4e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase BCAS2 PF05700.9 001284559.1_29523001_1 - 6.1e-81 270.9 8.5 7.4e-81 270.6 8.5 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) HAUS2 PF15003.4 001284559.1_29523001_1 - 0.0047 16.5 0.3 0.0074 15.9 0.3 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 THOC7 PF05615.11 001284559.1_29523001_1 - 0.015 15.4 2.3 0.015 15.4 2.3 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Mesd PF10185.7 001284559.1_29523001_1 - 0.08 12.7 2.7 4.6 7.0 0.2 2.2 1 1 0 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor CENP-F_leu_zip PF10473.7 001284559.1_29523001_1 - 0.43 10.5 8.0 0.96 9.3 8.1 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.8 001284559.1_29523001_1 - 0.49 10.6 11.7 1.1 9.4 2.1 3.2 1 1 1 3 3 3 0 Tup N-terminal PRKG1_interact PF15898.3 001284559.1_29523001_1 - 1.5 9.7 9.6 0.31 11.8 5.1 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Uso1_p115_C PF04871.11 001284559.1_29523001_1 - 2 8.7 5.7 2.7 8.3 4.5 1.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cep57_MT_bd PF06657.11 001284559.1_29523001_1 - 5.5 7.4 8.6 6.2 7.2 1.6 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Transferrin PF00405.15 001303546.1_24225001_1 - 4.5e-268 887.1 11.7 1.1e-174 580.1 0.4 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.5 001303546.1_24225001_1 - 1e-12 48.1 0.0 5.6e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.18 001303546.1_24225001_1 - 0.0096 15.2 0.1 1.5 8.0 0.0 2.7 2 1 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 DRMBL PF07522.12 001279748.1_24225001_1 - 4.7e-19 68.6 0.2 9.4e-19 67.6 0.2 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.5 001279748.1_24225001_1 - 2.6e-07 30.2 0.0 1.1e-06 28.2 0.0 2.0 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.25 001279748.1_24225001_1 - 0.0066 16.3 0.1 0.058 13.3 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF3290 PF11694.6 001279748.1_24225001_1 - 0.027 14.3 0.1 0.41 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) PARP PF00644.18 001279609.1_24226001_1 - 5.6e-23 81.5 5.9 5.7e-21 75.0 5.9 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.18 001279609.1_24226001_1 - 2.2e-15 56.8 3.1 1.4e-12 47.8 2.1 2.7 2 0 0 2 2 2 2 WWE domain TIR_2 PF13676.4 001279568.1_24222001_1 - 1e-10 41.7 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001279568.1_24222001_1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain HD PF01966.20 001279619.1_24224001_1 - 1.4e-18 67.1 0.0 4e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 HD domain SAM_2 PF07647.15 001279619.1_24224001_1 - 3.1e-10 39.9 0.0 6.3e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001279619.1_24224001_1 - 2.4e-09 37.4 0.0 5.6e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001279619.1_24224001_1 - 0.0085 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ste50p-SAM PF09235.8 001279619.1_24224001_1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif BST2 PF16716.3 001279631.1_24222001_1 - 7.6e-37 125.6 8.5 1e-36 125.2 8.5 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 MAD PF05557.11 001279631.1_24222001_1 - 9.2e-05 20.9 4.3 0.00011 20.6 4.3 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein ATG16 PF08614.9 001279631.1_24222001_1 - 0.0005 20.2 5.5 0.00076 19.6 5.5 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.9 001279631.1_24222001_1 - 0.0005 18.6 2.6 0.00059 18.4 2.6 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.6 001279631.1_24222001_1 - 0.0035 16.6 3.1 0.0038 16.4 2.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.10 001279631.1_24222001_1 - 0.0039 17.1 4.1 0.0081 16.1 4.1 1.5 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.6 001279631.1_24222001_1 - 0.0042 17.2 4.3 0.0069 16.5 4.3 1.3 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding IncA PF04156.12 001279631.1_24222001_1 - 0.0049 16.5 11.2 0.0099 15.6 11.2 1.6 1 1 0 1 1 1 1 IncA protein DUF4618 PF15397.4 001279631.1_24222001_1 - 0.0052 16.1 2.6 0.0065 15.8 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Spc7 PF08317.9 001279631.1_24222001_1 - 0.0058 15.4 3.1 0.0075 15.0 3.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein PRKG1_interact PF15898.3 001279631.1_24222001_1 - 0.0079 17.0 4.1 0.012 16.4 4.1 1.2 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain CCDC-167 PF15188.4 001279631.1_24222001_1 - 0.0086 16.3 2.5 0.012 15.8 1.7 1.6 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 Bap31 PF05529.10 001279631.1_24222001_1 - 0.0097 15.4 4.0 0.019 14.5 4.0 1.4 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF3584 PF12128.6 001279631.1_24222001_1 - 0.011 13.2 2.2 0.012 13.0 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.7 001279631.1_24222001_1 - 0.012 15.5 2.4 0.012 15.5 2.4 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.9 001279631.1_24222001_1 - 0.013 15.8 1.0 0.47 10.8 0.6 2.5 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.7 001279631.1_24222001_1 - 0.016 14.5 3.7 0.02 14.2 3.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Filament PF00038.19 001279631.1_24222001_1 - 0.019 14.4 6.0 0.058 12.8 5.9 1.6 1 1 0 1 1 1 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.7 001279631.1_24222001_1 - 0.021 14.9 3.1 0.029 14.5 3.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FliJ PF02050.14 001279631.1_24222001_1 - 0.026 14.6 3.8 0.049 13.7 3.8 1.3 1 1 0 1 1 1 0 Flagellar FliJ protein NRBF2 PF08961.8 001279631.1_24222001_1 - 0.03 13.8 0.2 0.04 13.4 0.2 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator CASP_C PF08172.10 001279631.1_24222001_1 - 0.031 13.5 0.7 0.031 13.5 0.7 1.5 1 1 0 1 1 1 0 CASP C terminal Reo_sigmaC PF04582.10 001279631.1_24222001_1 - 0.033 13.5 0.6 0.04 13.2 0.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein HAUS-augmin3 PF14932.4 001279631.1_24222001_1 - 0.034 13.5 3.8 0.041 13.3 3.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc24 PF08286.9 001279631.1_24222001_1 - 0.035 14.2 1.9 0.035 14.2 1.9 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.5 001279631.1_24222001_1 - 0.037 14.0 2.4 0.037 14.0 2.4 1.8 1 1 1 2 2 2 0 Tropomyosin like CENP-H PF05837.10 001279631.1_24222001_1 - 0.039 14.2 5.9 0.08 13.2 5.7 1.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) EMP24_GP25L PF01105.22 001279631.1_24222001_1 - 0.041 13.7 0.9 0.067 13.0 0.9 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD THOC7 PF05615.11 001279631.1_24222001_1 - 0.049 13.8 3.4 0.07 13.3 3.4 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Lipoprotein_7 PF01540.14 001279631.1_24222001_1 - 0.049 12.8 0.6 0.062 12.5 0.6 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Tropomyosin PF00261.18 001279631.1_24222001_1 - 0.054 12.7 5.4 0.2 10.8 1.5 1.8 1 1 0 1 1 1 0 Tropomyosin APG6 PF04111.10 001279631.1_24222001_1 - 0.067 12.4 3.8 0.085 12.1 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.20 001279631.1_24222001_1 - 0.07 13.2 2.2 0.098 12.8 2.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cob_adeno_trans PF01923.16 001279631.1_24222001_1 - 0.072 13.1 0.8 0.095 12.7 0.8 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF4200 PF13863.4 001279631.1_24222001_1 - 0.085 13.1 3.8 0.14 12.4 3.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1647 PF07801.9 001279631.1_24222001_1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) GAS PF13851.4 001279631.1_24222001_1 - 0.1 11.8 5.6 0.068 12.4 2.0 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding GrpE PF01025.17 001279631.1_24222001_1 - 0.12 11.9 4.4 0.06 12.9 1.8 1.7 1 1 1 2 2 2 0 GrpE Lebercilin PF15619.4 001279631.1_24222001_1 - 0.12 11.9 6.3 0.09 12.3 3.2 1.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mnd1 PF03962.13 001279631.1_24222001_1 - 0.15 11.8 3.0 0.19 11.4 3.0 1.1 1 0 0 1 1 1 0 Mnd1 family Tektin PF03148.12 001279631.1_24222001_1 - 0.16 10.5 6.6 0.57 8.7 1.4 2.0 1 1 1 2 2 2 0 Tektin family V_ATPase_I PF01496.17 001279631.1_24222001_1 - 0.17 9.6 1.2 0.2 9.4 1.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.10 001279631.1_24222001_1 - 0.17 11.7 2.9 3.1 7.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.11 001279631.1_24222001_1 - 0.17 12.4 2.1 0.26 11.8 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cluap1 PF10234.7 001279631.1_24222001_1 - 0.17 11.1 4.8 0.57 9.4 4.8 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF4472 PF14739.4 001279631.1_24222001_1 - 0.18 12.4 4.7 2.5 8.7 1.3 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF2205 PF10224.7 001279631.1_24222001_1 - 0.24 11.3 4.9 0.53 10.2 2.1 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Nup54 PF13874.4 001279631.1_24222001_1 - 0.24 11.3 5.6 0.47 10.4 3.0 1.8 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ZapB PF06005.10 001279631.1_24222001_1 - 0.26 11.6 6.4 0.22 11.9 1.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB KLRAQ PF10205.7 001279631.1_24222001_1 - 0.39 10.8 4.2 0.78 9.9 1.2 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein SlyX PF04102.10 001279631.1_24222001_1 - 0.41 11.2 5.7 0.68 10.5 0.5 2.4 1 1 2 3 3 3 0 SlyX Prefoldin_2 PF01920.18 001279631.1_24222001_1 - 0.46 10.3 5.4 1.5 8.7 5.4 1.7 1 1 0 1 1 1 0 Prefoldin subunit KELK PF15796.3 001279631.1_24222001_1 - 0.66 10.4 6.0 0.56 10.6 2.0 2.0 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ABC_tran_CTD PF16326.3 001279631.1_24222001_1 - 0.67 10.1 5.2 8 6.7 4.7 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain ADIP PF11559.6 001279631.1_24222001_1 - 0.79 9.7 6.8 0.48 10.4 2.0 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.13 001279631.1_24222001_1 - 1.4 8.6 7.5 2.8 7.7 2.4 3.0 1 1 2 3 3 3 0 Septum formation initiator CLZ PF16526.3 001279631.1_24222001_1 - 1.7 8.9 6.1 0.31 11.3 1.7 2.0 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels OmpH PF03938.12 001279631.1_24222001_1 - 1.8 8.4 7.2 6 6.7 7.2 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LRR_8 PF13855.4 001279583.1_24226001_1 - 1.7e-50 168.5 96.2 2.7e-11 42.9 0.3 10.6 4 2 10 14 14 14 13 Leucine rich repeat TIR PF01582.18 001279583.1_24226001_1 - 1.3e-35 122.6 0.1 2.2e-35 121.9 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001279583.1_24226001_1 - 2.7e-30 103.7 52.9 1.9e-06 27.9 1.5 11.7 8 2 5 13 13 13 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001279583.1_24226001_1 - 4.1e-11 42.6 14.5 4.7e-05 22.8 0.0 4.6 3 2 2 5 5 5 4 Leucine-rich repeat TIR_2 PF13676.4 001279583.1_24226001_1 - 2.6e-09 37.2 0.1 4.8e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001279583.1_24226001_1 - 2.9e-08 32.9 51.2 0.16 12.4 0.4 15.3 13 4 1 14 14 14 3 Leucine Rich Repeat LRR_6 PF13516.4 001279583.1_24226001_1 - 1.6e-06 27.6 49.1 0.33 11.0 0.4 13.4 16 0 0 16 16 16 4 Leucine Rich repeat DUF1863 PF08937.9 001279583.1_24226001_1 - 0.00013 22.2 0.5 0.00056 20.1 0.5 2.0 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) Pam16 PF03656.11 001347988.1_08022001_3 - 9.2e-59 196.9 1.8 1.1e-58 196.7 1.8 1.0 1 0 0 1 1 1 1 Pam16 Integrase_Zn PF02022.17 001347988.1_08022001_3 - 0.21 11.4 2.0 4.3 7.2 0.8 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain CD20 PF04103.13 001009388.2_22424001_2 - 1.2e-48 165.1 3.1 1.7e-48 164.5 3.1 1.2 1 0 0 1 1 1 1 CD20-like family Neur_chan_memb PF02932.14 001310194.1_33426001_1 - 9.5e-80 267.9 11.4 3.4e-56 190.8 12.5 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.21 001310194.1_33426001_1 - 1.9e-72 243.1 1.7 2.7e-72 242.6 1.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.7 001310194.1_33426001_1 - 0.31 10.3 8.2 0.084 12.1 4.7 1.8 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Oest_recep PF02159.13 001317072.1_52124001_1 - 6.2e-68 227.5 5.4 1.2e-67 226.6 5.4 1.5 1 0 0 1 1 1 1 Oestrogen receptor Hormone_recep PF00104.28 001317072.1_52124001_1 - 1.7e-34 119.1 3.3 2.6e-34 118.5 3.3 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001317072.1_52124001_1 - 1.5e-31 108.5 13.9 2.4e-31 107.9 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ESR1_C PF12743.5 001317072.1_52124001_1 - 1.9e-26 91.4 3.9 3.9e-26 90.4 3.9 1.6 1 0 0 1 1 1 1 Oestrogen-type nuclear receptor final C-terminal Jiv90 PF14901.4 001317072.1_52124001_1 - 0.25 11.4 4.4 1 9.5 4.1 2.1 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Interferon PF00143.17 001293099.1_11722001_3 - 8e-65 217.8 5.2 9.5e-65 217.5 5.2 1.1 1 0 0 1 1 1 1 Interferon alpha/beta domain DDHD PF02862.15 001293099.1_11722001_3 - 0.0067 16.5 0.0 0.0073 16.3 0.0 1.1 1 0 0 1 1 1 1 DDHD domain Hormone_1 PF00103.18 001287198.1_52722001_1 - 2e-46 158.3 0.0 2.4e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Somatotropin hormone family ODC_AZ PF02100.15 001291898.1_52223001_1 - 3.3e-20 72.1 0.0 5.1e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Sod_Fe_C PF02777.16 001319878.1_08522001_1 - 1.3e-37 127.9 0.0 2.4e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.20 001319878.1_08522001_1 - 2.4e-33 114.3 3.1 3.5e-33 113.8 3.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Methyltransf_3 PF01596.15 001282046.1_01324001_1 - 7.5e-13 48.0 0.0 1.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001282046.1_01324001_1 - 1.6e-10 41.9 0.1 3.6e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain LRR_8 PF13855.4 001282046.1_01324001_1 - 6e-07 29.0 1.6 6e-07 29.0 1.6 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282046.1_01324001_1 - 9.9e-06 25.7 4.1 0.00059 20.0 0.2 3.3 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001282046.1_01324001_1 - 0.00021 20.7 0.1 0.00071 19.0 0.1 1.9 1 1 0 1 1 1 1 Leucine-rich repeat PCMT PF01135.17 001282046.1_01324001_1 - 0.049 13.3 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LRR_1 PF00560.31 001282046.1_01324001_1 - 3.7 8.3 5.6 1.1e+02 3.8 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat Ribosomal_S30 PF04758.12 001304904.1_01321001_1 - 5.7e-31 106.4 12.9 8.5e-31 105.8 12.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.21 001304904.1_01321001_1 - 4.4e-14 51.8 0.0 6.1e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 001304904.1_01321001_1 - 0.0021 17.7 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S17e PF00833.16 001304891.1_01321001_3 - 3.5e-70 233.5 0.6 4e-70 233.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S9 PF00380.17 001304899.1_01321001_2 - 4.7e-34 117.4 0.3 5.3e-34 117.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L21e PF01157.16 001304847.1_01322001_1 - 4.6e-52 173.8 8.8 4.6e-52 173.8 8.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e CLP_protease PF00574.21 001304847.1_01322001_1 - 0.069 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Clp protease Ribosomal_S7 PF00177.19 001304926.1_01322001_3 - 4.1e-37 127.0 1.0 5e-37 126.7 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Dynactin_p22 PF07426.9 001304931.1_01322001_2 - 3e-58 196.2 0.7 3.6e-58 196.0 0.7 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 DUF4011 PF13195.4 001304931.1_01322001_2 - 0.0038 17.1 0.6 0.0057 16.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4011) DUF948 PF06103.9 001304931.1_01322001_2 - 0.026 14.7 0.9 1.7 8.8 0.2 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spidroin_MaSp PF11260.6 001304931.1_01322001_2 - 0.028 14.6 0.1 0.06 13.5 0.1 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Jnk-SapK_ap_N PF09744.7 001304931.1_01322001_2 - 0.033 14.3 3.2 0.021 14.9 1.6 1.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4515 PF14988.4 001304931.1_01322001_2 - 0.036 13.8 4.5 0.073 12.8 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DivIC PF04977.13 001304931.1_01322001_2 - 0.046 13.4 6.0 0.31 10.7 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator Ribosomal_60s PF00428.17 001304844.1_01321001_2 - 6.4e-25 87.4 1.6 9.2e-25 86.9 1.6 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DEC-1_N PF04625.11 001304844.1_01321001_2 - 0.12 11.3 1.3 0.15 10.9 1.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RNA_pol_Rpb8 PF03870.13 001304900.1_01322001_3 - 4.1e-54 182.4 0.2 4.6e-54 182.2 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.3 001304900.1_01322001_3 - 7.1e-05 22.7 0.0 0.057 13.3 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G SUI1 PF01253.20 001304841.1_01321001_3 - 6.3e-28 97.0 0.9 9.5e-28 96.4 0.9 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 RNase_H PF00075.22 001285939.1_01323001_1 - 7.6e-46 155.7 0.0 1.2e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285939.1_01323001_1 - 1.3e-18 66.9 2.9 3.1e-18 65.7 2.9 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285939.1_01323001_1 - 0.00089 18.8 0.0 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like Crystallin PF00525.16 001304874.1_01322001_1 - 5.1e-30 103.3 7.2 8.8e-30 102.6 7.2 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.19 001304874.1_01322001_1 - 2.6e-25 88.4 0.1 3.2e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Ribosomal_L35Ae PF01247.16 001304936.1_01321001_1 - 5.6e-48 161.0 0.4 6.3e-48 160.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.16 001304936.1_01321001_1 - 0.0097 16.0 0.0 0.88 9.7 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.7 001304936.1_01321001_1 - 0.041 13.5 0.2 0.2 11.3 0.0 2.2 2 1 1 3 3 3 0 Putative transposon-encoded protein (DUF2080) DUF846 PF05832.10 001281868.1_01322001_3 - 1.7e-55 186.8 10.1 2.1e-55 186.4 10.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMC PF07810.11 001281868.1_01322001_3 - 0.071 13.6 3.3 0.13 12.7 3.3 1.7 1 1 0 1 1 1 0 TMC domain TMEM192 PF14802.4 001281868.1_01322001_3 - 0.092 11.7 0.2 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 TMEM192 family HXXEE PF13787.4 001281868.1_01322001_3 - 1.4 9.6 8.2 9.1 7.0 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif Ribosomal_S8e PF01201.20 001304920.1_01322001_3 - 3.1e-63 211.9 1.0 3.6e-63 211.6 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_S17_N PF16205.3 001304884.1_01322001_3 - 5.4e-37 125.9 0.8 5.4e-37 125.9 0.8 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.18 001304884.1_01322001_3 - 1.4e-29 101.8 1.7 2.5e-29 101.1 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.9 001304884.1_01322001_3 - 0.12 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Ribosomal_L13 PF00572.16 001304873.1_01322001_1 - 4.1e-10 39.9 0.5 7.8e-09 35.7 0.0 2.7 2 1 0 2 2 2 1 Ribosomal protein L13 Ribosomal_L28e PF01778.15 001304854.1_01321001_2 - 3.9e-36 124.1 1.8 4.8e-36 123.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family MipZ PF09140.9 001304854.1_01321001_2 - 0.022 13.9 0.1 0.023 13.8 0.1 1.2 1 0 0 1 1 1 0 ATPase MipZ Ribosomal_L7Ae PF01248.24 001304913.1_01321001_3 - 2.8e-30 103.8 1.8 3.5e-30 103.5 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HAD PF12710.5 001304913.1_01321001_3 - 0.085 13.1 0.0 0.098 12.9 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short_C2 PF13561.4 001278922.1_01322001_1 - 3.8e-62 209.8 0.1 4.8e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001278922.1_01322001_1 - 2e-50 170.9 0.3 2.4e-50 170.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001278922.1_01322001_1 - 5.2e-11 42.6 0.1 7.7e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.8 001278922.1_01322001_1 - 0.019 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DFP PF04127.13 001278922.1_01322001_1 - 0.042 13.6 0.8 0.14 11.9 0.3 1.8 1 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.15 001278922.1_01322001_1 - 0.051 14.0 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Orn_Arg_deC_N PF02784.14 001291458.1_01329001_2 - 9.8e-64 215.0 0.1 1.3e-63 214.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291458.1_01329001_2 - 4.3e-24 84.6 0.0 7.4e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ribosomal_L16 PF00252.16 001304855.1_01322001_3 - 1.5e-44 151.0 0.3 1.9e-44 150.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e OST-HTH PF12872.5 001110448.1_22423001_1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Band_7 PF01145.23 001110448.1_22423001_3 - 9.1e-27 94.1 1.5 1.2e-26 93.6 1.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.6 001110448.1_22423001_3 - 0.013 15.6 0.4 0.02 14.9 0.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 CFTR_R PF14396.4 001048009.1_22429001_2 - 7.1e-100 332.8 1.0 1.1e-99 332.2 1.0 1.3 1 0 0 1 1 1 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain ABC_membrane PF00664.21 001048009.1_22429001_2 - 2.7e-93 312.5 43.4 9.6e-50 169.6 20.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001048009.1_22429001_2 - 9.1e-59 197.7 0.0 1.3e-32 113.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.4 001048009.1_22429001_2 - 1.8e-07 31.1 1.1 0.029 14.0 0.1 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.17 001048009.1_22429001_2 - 4.8e-07 29.3 1.1 0.062 12.6 0.0 3.7 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.18 001048009.1_22429001_2 - 2.3e-06 26.8 0.0 0.011 14.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.4 001048009.1_22429001_2 - 4.5e-06 26.1 1.0 0.00092 18.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.14 001048009.1_22429001_2 - 5.5e-06 26.3 0.4 0.026 14.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.15 001048009.1_22429001_2 - 5.1e-05 23.3 1.1 0.015 15.2 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.4 001048009.1_22429001_2 - 0.00028 21.2 0.0 0.51 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.21 001048009.1_22429001_2 - 0.00045 20.2 0.4 0.081 12.9 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.10 001048009.1_22429001_2 - 0.00076 19.3 0.4 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.10 001048009.1_22429001_2 - 0.002 17.3 0.7 0.21 10.7 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin ArgK PF03308.14 001048009.1_22429001_2 - 0.0036 16.2 1.0 0.013 14.4 0.1 2.1 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.4 001048009.1_22429001_2 - 0.0047 17.1 0.8 3.2 7.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.13 001048009.1_22429001_2 - 0.0055 16.5 0.1 0.19 11.5 0.0 2.6 3 0 0 3 3 2 1 NTPase FtsK_SpoIIIE PF01580.16 001048009.1_22429001_2 - 0.021 14.1 0.5 2.6 7.2 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.4 001048009.1_22429001_2 - 0.034 13.7 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.12 001048009.1_22429001_2 - 0.036 13.9 3.1 4.4 7.1 0.2 3.4 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.15 001048009.1_22429001_2 - 0.036 13.9 0.6 12 5.7 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.20 001048009.1_22429001_2 - 0.037 12.9 0.1 0.96 8.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.4 001048009.1_22429001_2 - 0.043 14.0 0.1 15 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.17 001048009.1_22429001_2 - 0.055 12.9 2.2 5.9 6.3 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.11 001048009.1_22429001_2 - 0.058 13.5 0.1 15 5.7 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.7 001048009.1_22429001_2 - 0.12 11.1 0.6 2.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.23 001048009.1_22429001_2 - 0.15 11.5 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.21 001048009.1_22429001_2 - 0.15 12.0 0.6 23 4.9 0.2 2.7 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.4 001048009.1_22429001_2 - 0.18 12.2 11.4 0.92 9.8 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_18 PF13238.4 001048009.1_22429001_2 - 0.18 12.2 0.1 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.4 001048009.1_22429001_2 - 0.22 10.9 0.6 14 5.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain 3Beta_HSD PF01073.17 001246194.1_22424001_1 - 7.2e-113 376.1 0.0 8.7e-113 375.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.19 001246194.1_22424001_1 - 4.1e-19 68.9 0.0 5.9e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.10 001246194.1_22424001_1 - 3.4e-15 55.8 0.1 1.2e-14 54.0 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.3 001246194.1_22424001_1 - 1.9e-11 43.8 0.1 9e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.13 001246194.1_22424001_1 - 1.9e-09 37.0 0.0 3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.4 001246194.1_22424001_1 - 8.1e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.15 001246194.1_22424001_1 - 3.9e-05 22.7 0.0 6.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.16 001246194.1_22424001_1 - 0.00089 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.11 001246194.1_22424001_1 - 0.00092 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.8 001246194.1_22424001_1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Ald_Xan_dh_C2 PF02738.16 001290238.1_22428001_1 - 2.4e-185 617.0 0.0 3.2e-185 616.6 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001290238.1_22428001_1 - 1.2e-45 155.2 0.0 3.2e-45 153.8 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001290238.1_22428001_1 - 1.4e-32 112.1 0.3 2.7e-32 111.3 0.3 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001290238.1_22428001_1 - 1.7e-29 101.5 0.3 4.1e-29 100.2 0.3 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001290238.1_22428001_1 - 3.3e-28 97.7 0.0 5.2e-26 90.7 0.0 3.1 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001290238.1_22428001_1 - 6.8e-08 32.2 0.1 6.8e-08 32.2 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001290238.1_22428001_1 - 0.18 11.5 5.7 0.034 13.8 1.4 2.1 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 7tm_1 PF00001.19 001009861.1_22423001_1 - 7.5e-18 64.6 13.3 7.5e-18 64.6 13.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.13 001009861.1_22423001_1 - 4.3e-05 23.4 1.7 4.3e-05 23.4 1.7 2.7 2 1 1 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srv PF10323.7 001009861.1_22423001_1 - 0.0013 18.0 14.2 0.0014 17.9 12.5 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv RPA PF10134.7 001009861.1_22423001_1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Replication initiator protein A NPCC PF08058.9 001009861.1_22423001_1 - 2.8 7.9 8.2 64 3.5 4.1 3.2 2 1 0 2 2 2 0 Nuclear pore complex component SAA PF00277.16 001281804.1_52221001_1 - 3.2e-51 171.9 2.6 3.7e-51 171.7 2.6 1.0 1 0 0 1 1 1 1 Serum amyloid A protein Ldh_1_N PF00056.21 001280640.1_52224001_2 - 3.8e-50 169.5 0.5 5.5e-50 169.0 0.5 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001280640.1_52224001_2 - 3.1e-23 82.4 0.0 6.5e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.14 001280640.1_52224001_2 - 0.025 14.0 0.4 0.079 12.4 0.0 2.0 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Pyr_redox_2 PF07992.12 001280640.1_52224001_2 - 0.038 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ferritin PF00210.22 001280630.1_52222001_1 - 1.5e-30 105.8 2.1 1.8e-30 105.6 2.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain ANAPC4 PF12896.5 001280630.1_52222001_1 - 0.013 14.9 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 V_cholerae_RfbT PF05575.9 001280630.1_52222001_1 - 0.2 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein Na_Ca_ex PF01699.22 001280647.1_52227001_1 - 2.5e-55 186.5 48.2 3e-29 101.8 22.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SNARE_assoc PF09335.9 001280647.1_52227001_1 - 0.0017 18.7 0.0 0.0017 18.7 0.0 2.9 3 0 0 3 3 3 1 SNARE associated Golgi protein V-set PF07686.15 001280605.1_52223001_3 - 5.9e-14 52.0 0.0 8.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001280605.1_52223001_3 - 0.0001 22.7 0.0 0.00023 21.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001280605.1_52223001_3 - 0.039 14.2 0.1 0.19 12.0 0.1 2.0 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.14 001280605.1_52223001_3 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin I-set domain JmjC PF02373.20 001280667.1_52228001_1 - 2.1e-08 34.5 0.0 6.4e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase CD34_antigen PF06365.10 001281809.1_52225001_3 - 1.6e-74 249.9 0.0 2.2e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family RNase_H PF00075.22 001285509.1_52222001_1 - 2.8e-38 131.2 0.0 4.7e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285509.1_52222001_1 - 6.1e-19 67.9 1.3 1.1e-18 67.1 1.3 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin CD34_antigen PF06365.10 001281810.1_52225001_1 - 2.1e-18 66.6 1.0 2.9e-18 66.1 1.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family CD34_antigen PF06365.10 001281810.1_52225001_3 - 4.5e-47 160.2 0.3 6.3e-47 159.8 0.3 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family IL1 PF00340.17 001280652.1_52222001_1 - 3.6e-45 152.4 0.0 5.7e-45 151.7 0.0 1.3 1 0 0 1 1 1 1 Interleukin-1 / 18 IL1_propep PF02394.14 001280652.1_52222001_1 - 2.1e-37 128.2 0.9 4.3e-37 127.2 0.2 1.8 2 0 0 2 2 2 1 Interleukin-1 propeptide 7tm_1 PF00001.19 001280859.1_29224001_2 - 5.4e-40 137.2 14.8 7.1e-40 136.8 14.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001280859.1_29224001_2 - 7.4e-08 31.9 15.0 1.2e-07 31.3 15.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001280859.1_29224001_2 - 0.00036 20.2 9.8 0.00065 19.4 1.7 2.1 2 0 0 2 2 2 2 Olfactory receptor zf-LITAF-like PF10601.7 001280859.1_29224001_2 - 6.3 7.0 9.8 9.2 6.5 0.7 3.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF805 PF05656.12 001280859.1_29224001_2 - 8.1 6.8 8.1 0.71 10.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF805) SR-25 PF10500.7 033706.1_49823120_1 - 2.2e-75 253.1 17.5 3.2e-75 252.5 17.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.3 033706.1_49823120_1 - 0.13 11.8 16.1 0.22 11.1 16.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Med19 PF10278.7 033706.1_49823120_1 - 0.2 11.4 15.4 0.36 10.6 15.4 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 IMUP PF15761.3 033706.1_49823120_1 - 0.21 12.2 24.0 0.45 11.1 24.0 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF4614 PF15391.4 033706.1_49823120_1 - 0.53 10.1 6.5 0.84 9.5 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Dehydrin PF00257.17 033706.1_49823120_1 - 0.58 10.5 13.2 1 9.7 13.2 1.4 1 0 0 1 1 1 0 Dehydrin FAM199X PF15814.3 033706.1_49823120_1 - 0.68 8.8 6.5 0.98 8.3 6.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X AP3D1 PF06375.9 033706.1_49823120_1 - 2 8.5 14.9 3.2 7.9 14.9 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF3827 PF12877.5 033706.1_49823120_1 - 3.3 5.8 8.3 4.5 5.4 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SR-25 PF10500.7 033706.1_49823120_2 - 4.1e-08 33.0 13.4 4.1e-08 33.0 13.4 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SR-25 PF10500.7 033706.1_49823120_3 - 0.0031 17.0 0.2 0.0031 17.0 0.2 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein zinc_ribbon_6 PF14599.4 001163595.1_39522001_1 - 7.7e-28 96.2 1.8 7.7e-28 96.2 1.8 3.9 2 1 2 4 4 2 1 Zinc-ribbon zf-CHY PF05495.10 001163595.1_39522001_1 - 4.7e-21 75.0 22.3 4.7e-21 75.0 22.3 3.9 3 1 0 3 3 2 2 CHY zinc finger zf-RING_2 PF13639.4 001163595.1_39522001_1 - 4.5e-11 42.7 5.2 4.5e-11 42.7 5.2 5.7 4 2 2 6 6 4 1 Ring finger domain zf-C3HC4 PF00097.23 001163595.1_39522001_1 - 2.3e-07 30.4 4.9 2.3e-07 30.4 4.9 6.1 4 1 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001163595.1_39522001_1 - 4.4e-07 29.5 5.5 4.4e-07 29.5 5.5 5.6 5 2 1 6 6 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001163595.1_39522001_1 - 2e-06 27.6 2.3 2e-06 27.6 2.3 4.4 5 2 1 6 6 5 1 RING-type zinc-finger zf-RING_5 PF14634.4 001163595.1_39522001_1 - 4.7e-06 26.3 4.8 4.7e-06 26.3 4.8 6.3 3 2 1 4 4 3 1 zinc-RING finger domain zf-RING_11 PF17123.3 001163595.1_39522001_1 - 6.8e-06 25.6 2.5 6.8e-06 25.6 2.5 5.2 7 1 0 7 7 6 1 RING-like zinc finger Prok-RING_4 PF14447.4 001163595.1_39522001_1 - 8e-06 25.5 0.5 8e-06 25.5 0.5 6.0 4 2 3 7 7 4 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.4 001163595.1_39522001_1 - 1.1e-05 25.0 5.9 1.1e-05 25.0 5.9 6.4 2 1 3 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001163595.1_39522001_1 - 0.028 14.6 7.4 0.028 14.6 7.4 5.2 3 2 1 4 4 3 0 RING-H2 zinc finger domain KRAB PF01352.25 001348689.1_26224001_3 - 3.3e-24 84.1 0.2 5.7e-24 83.4 0.2 1.4 1 0 0 1 1 1 1 KRAB box Peptidase_M10 PF00413.22 001348795.1_49823001_1 - 1.3e-56 190.6 0.0 1.9e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.16 001348795.1_49823001_1 - 1.7e-09 37.6 0.0 2.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Metallopep PF12044.6 001348795.1_49823001_1 - 0.0073 14.8 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M54 PF07998.9 001348795.1_49823001_1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_5 PF13688.4 001348795.1_49823001_1 - 0.076 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.22 001348795.1_49823001_1 - 0.11 11.9 0.7 2.8 7.4 0.1 2.4 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.4 001348795.1_49823001_1 - 0.13 12.6 1.1 0.27 11.6 1.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ECH_1 PF00378.18 001280141.1_39724001_3 - 3.8e-29 101.6 0.0 5.2e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chromo PF00385.22 001280141.1_39724001_3 - 1.5e-15 56.7 1.4 2.9e-15 55.8 1.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ECH_2 PF16113.3 001280141.1_39724001_3 - 2.4e-11 43.6 0.0 3.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Mtf2_C PF14061.4 001280141.1_39724001_3 - 0.056 13.5 0.8 0.12 12.4 0.8 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 XTBD PF11952.6 001280141.1_39724001_3 - 0.091 12.4 0.6 2.7 7.7 0.0 2.8 1 1 1 2 2 2 0 XRN-Two Binding Domain, XTBD PRY PF13765.4 001290237.1_22424001_3 - 3.1e-17 61.8 0.1 6e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.26 001290237.1_22424001_3 - 1.2e-15 57.5 0.0 3e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_4 PF15227.4 001290237.1_22424001_3 - 2.5e-10 40.2 9.6 2.5e-10 40.2 9.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.22 001290237.1_22424001_3 - 6.1e-09 35.8 2.3 6.1e-09 35.8 2.3 3.2 2 1 0 2 2 1 1 B-box zinc finger zf-RING_UBOX PF13445.4 001290237.1_22424001_3 - 2.6e-08 33.6 2.3 2.6e-08 33.6 2.3 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001290237.1_22424001_3 - 2.5e-06 27.1 9.3 2.5e-06 27.1 9.3 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001290237.1_22424001_3 - 5.6e-06 26.4 8.5 5.6e-06 26.4 8.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.4 001290237.1_22424001_3 - 1.3e-05 24.8 6.3 1.3e-05 24.8 6.3 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.13 001290237.1_22424001_3 - 2.4e-05 24.3 0.3 0.00011 22.2 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-C3HC4_2 PF13923.4 001290237.1_22424001_3 - 0.00024 20.7 9.7 0.00024 20.7 9.7 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.7 001290237.1_22424001_3 - 0.00044 19.3 20.4 0.00044 19.3 20.4 1.9 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Trm112p PF03966.14 001290237.1_22424001_3 - 0.0016 18.8 2.8 0.0044 17.4 0.8 2.8 3 0 0 3 3 3 1 Trm112p-like protein zf-RING_4 PF14570.4 001290237.1_22424001_3 - 0.0059 16.2 2.8 0.022 14.3 2.8 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.4 001290237.1_22424001_3 - 0.0097 15.6 2.7 0.078 12.7 2.7 2.4 1 1 0 1 1 1 1 zf-RING of BARD1-type protein DUF4618 PF15397.4 001290237.1_22424001_3 - 0.011 15.0 4.1 0.011 15.0 4.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Flagellin_N PF00669.18 001290237.1_22424001_3 - 0.013 15.4 0.8 0.013 15.4 0.8 2.0 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region zf-RING_5 PF14634.4 001290237.1_22424001_3 - 0.017 14.9 7.9 0.017 14.9 7.9 3.3 2 2 0 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.6 001290237.1_22424001_3 - 0.028 14.1 7.0 0.09 12.5 4.9 2.7 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit FliD_C PF07195.10 001290237.1_22424001_3 - 0.03 13.6 0.3 0.03 13.6 0.3 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.8 001290237.1_22424001_3 - 0.1 12.7 17.0 0.2 11.7 17.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RDM PF11002.6 001290237.1_22424001_3 - 0.12 12.2 1.5 0.13 12.1 0.0 1.8 2 0 0 2 2 1 0 RFPL defining motif (RDM) DUF4407 PF14362.4 001290237.1_22424001_3 - 0.3 10.3 10.5 0.019 14.2 4.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-RING_10 PF16685.3 001290237.1_22424001_3 - 0.34 11.0 11.3 0.039 14.0 5.3 2.7 2 1 0 2 2 2 0 zinc RING finger of MSL2 FANCL_C PF11793.6 001290237.1_22424001_3 - 0.41 10.7 14.6 0.037 14.1 6.8 3.1 3 1 0 3 3 3 0 FANCL C-terminal domain Gp-FAR-1 PF05823.10 001290237.1_22424001_3 - 1.3 9.1 14.4 0.14 12.3 2.3 2.9 2 1 1 3 3 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) LMBR1 PF04791.14 001290237.1_22424001_3 - 1.4 7.6 7.0 1.8 7.2 7.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IBR PF01485.19 001290237.1_22424001_3 - 2.7 8.2 15.6 0.18 11.9 3.3 3.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain ApoLp-III PF07464.9 001290237.1_22424001_3 - 3.2 7.7 16.7 34 4.4 15.7 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Prok-RING_4 PF14447.4 001290237.1_22424001_3 - 5.2 6.9 14.7 0.24 11.2 7.6 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Cob_adeno_trans PF01923.16 001290237.1_22424001_3 - 5.7 6.9 8.5 2.3 8.2 1.8 2.4 2 1 1 3 3 2 0 Cobalamin adenosyltransferase zf-RING_UBOX PF13445.4 001280099.1_35723001_1 - 1e-11 44.5 6.5 2.2e-11 43.5 3.7 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001280099.1_35723001_1 - 2.8e-11 43.2 8.4 2.8e-11 43.2 8.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.23 001280099.1_35723001_1 - 5.4e-10 38.8 7.2 1.4e-09 37.5 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.22 001280099.1_35723001_1 - 2.4e-09 37.1 2.6 2.4e-09 37.1 2.6 3.1 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4_2 PF13923.4 001280099.1_35723001_1 - 1.7e-08 34.1 7.0 3.2e-07 29.9 8.1 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SPRY PF00622.26 001280099.1_35723001_1 - 4.5e-08 33.1 2.0 5.9e-08 32.7 0.2 2.0 2 0 0 2 2 2 1 SPRY domain zf-RING_2 PF13639.4 001280099.1_35723001_1 - 5.5e-07 29.6 7.0 5.5e-07 29.6 7.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.4 001280099.1_35723001_1 - 1.8e-06 27.7 5.3 1.8e-06 27.7 5.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001280099.1_35723001_1 - 4.2e-06 26.4 5.3 4.2e-06 26.4 5.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.4 001280099.1_35723001_1 - 0.00089 18.9 4.7 0.0038 16.9 4.7 2.1 1 1 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.13 001280099.1_35723001_1 - 0.0024 17.9 0.1 0.0093 16.0 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.6 001280099.1_35723001_1 - 0.003 17.2 4.3 0.0074 15.9 4.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.3 001280099.1_35723001_1 - 0.0077 16.2 4.1 0.0077 16.2 4.1 2.3 2 1 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.4 001280099.1_35723001_1 - 0.017 14.8 9.7 0.017 14.8 9.7 2.7 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 FAM76 PF16046.3 001280099.1_35723001_1 - 0.077 12.2 11.5 0.16 11.2 11.5 1.5 1 0 0 1 1 1 0 FAM76 protein UBZ_FAAP20 PF15750.3 001280099.1_35723001_1 - 0.097 12.5 2.2 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-RING_4 PF14570.4 001280099.1_35723001_1 - 0.21 11.2 5.2 1.6 8.4 5.4 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain YojJ PF10372.7 001280099.1_35723001_1 - 0.84 9.6 7.8 4 7.5 0.4 2.9 3 0 0 3 3 2 0 Bacterial membrane-spanning protein N-terminus Allexi_40kDa PF05549.9 001280099.1_35723001_1 - 1.1 8.5 3.6 1.3 8.3 2.6 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein zf-rbx1 PF12678.5 001280099.1_35723001_1 - 1.2 9.4 13.6 0.041 14.0 4.5 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-Di19 PF05605.10 001280099.1_35723001_1 - 1.9 8.7 9.1 8.5 6.6 0.1 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.3 001280099.1_35723001_1 - 2 8.1 5.6 10 5.8 3.8 2.8 2 1 0 2 2 2 0 RING-like zinc finger DUF4407 PF14362.4 001280099.1_35723001_1 - 5.2 6.2 9.4 7.7 5.6 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rad50_zn_hook PF04423.12 001280099.1_35723001_1 - 8 6.3 9.2 1.4 8.7 0.1 3.7 4 0 0 4 4 4 0 Rad50 zinc hook motif Lectin_C PF00059.19 001309925.1_31522001_1 - 8.2e-12 45.7 0.4 8.2e-12 45.7 0.4 2.2 1 1 1 2 2 2 1 Lectin C-type domain UL45 PF05473.10 001309925.1_31522001_1 - 7.4e-06 25.6 0.5 1.2e-05 24.9 0.5 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001309925.1_31522001_1 - 0.0002 20.5 1.6 0.0002 20.5 1.6 1.6 1 1 0 2 2 2 1 Chordopoxvirus A33R protein DUF2678 PF10856.6 001309925.1_31522001_1 - 0.028 14.2 0.1 0.044 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Lectin_C PF00059.19 001309932.1_31522001_2 - 6e-12 46.1 5.8 7.4e-12 45.8 1.2 2.3 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.10 001309932.1_31522001_2 - 3.8e-05 23.3 0.2 0.00036 20.1 0.2 2.1 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001309932.1_31522001_2 - 7.2e-05 22.0 0.2 0.00015 21.0 0.2 1.5 1 0 0 1 1 1 1 Chordopoxvirus A33R protein NUP PF06516.9 001309932.1_31522001_2 - 0.033 13.3 0.1 0.05 12.7 0.1 1.3 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Lectin_C PF00059.19 001309927.1_31522001_2 - 1.4e-11 44.9 0.1 1.4e-11 44.9 0.1 1.9 1 1 1 2 2 2 1 Lectin C-type domain UL45 PF05473.10 001309927.1_31522001_2 - 0.00012 21.7 0.2 0.0002 20.9 0.0 1.5 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001309927.1_31522001_2 - 0.0022 17.1 0.2 0.0037 16.4 0.2 1.4 1 0 0 1 1 1 1 Chordopoxvirus A33R protein LMBR1 PF04791.14 001309927.1_31522001_2 - 0.017 13.9 0.3 0.025 13.4 0.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ly49 PF08391.8 001309941.1_31522001_1 - 5.5e-40 136.3 8.4 5.5e-40 136.3 8.4 2.2 2 0 0 2 2 2 1 Ly49-like protein, N-terminal region Lectin_C PF00059.19 001309941.1_31522001_1 - 7.7e-17 61.9 4.8 1.5e-16 61.0 4.8 1.5 1 0 0 1 1 1 1 Lectin C-type domain MHC_II_beta PF00969.17 001309922.1_31522001_3 - 1.8e-36 124.0 0.3 2.7e-36 123.4 0.3 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001309922.1_31522001_3 - 1.1e-23 83.4 0.2 2.7e-23 82.1 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.10 001309922.1_31522001_3 - 0.023 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF202 PF02656.13 001309922.1_31522001_3 - 0.056 13.8 0.6 0.082 13.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) ig PF00047.23 001309922.1_31522001_3 - 0.068 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain DAP10 PF07213.9 001309947.1_31521001_1 - 0.00073 19.3 2.9 0.001 18.9 2.9 1.2 1 0 0 1 1 1 1 DAP10 membrane protein IncA PF04156.12 001309947.1_31521001_1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 IncA protein Syndecan PF01034.18 001309947.1_31521001_1 - 0.22 11.4 0.4 0.35 10.7 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain Prion PF00377.16 001309920.1_31522001_1 - 1.4e-35 121.5 3.6 1.8e-35 121.2 3.6 1.1 1 0 0 1 1 1 1 Prion/Doppel alpha-helical domain Prion_bPrPp PF11587.6 001309920.1_31522001_1 - 2.1e-17 62.5 3.1 4.1e-17 61.6 3.1 1.5 1 0 0 1 1 1 1 Major prion protein bPrPp - N terminal MNSV_P7B PF06692.9 001309920.1_31522001_1 - 1.2 9.0 5.2 3.6 7.5 0.2 2.5 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein HD PF01966.20 001309948.1_31524001_1 - 6.9e-17 61.7 0.0 2.4e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 HD domain SAM_2 PF07647.15 001309948.1_31524001_1 - 6.1e-14 51.7 0.1 1.2e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001309948.1_31524001_1 - 2.8e-11 43.5 0.3 1.1e-10 41.7 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001309948.1_31524001_1 - 0.012 15.2 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Lectin_C PF00059.19 001309929.1_31522001_1 - 6e-15 55.8 2.4 6e-15 55.8 2.4 2.0 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.10 001309929.1_31522001_1 - 1.2e-05 25.0 0.8 2.1e-05 24.1 0.8 1.5 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001309929.1_31522001_1 - 2.7e-05 23.4 0.7 5.2e-05 22.5 0.7 1.4 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Lectin_C PF00059.19 001309936.1_31522001_1 - 6.3e-17 62.1 4.0 1.1e-16 61.3 4.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.10 001309936.1_31522001_1 - 0.0009 18.8 0.7 0.0009 18.8 0.7 2.0 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001309936.1_31522001_1 - 0.0084 15.3 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Ly49 PF08391.8 001309936.1_31522001_1 - 3.3 7.9 11.0 36 4.6 11.0 2.5 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Lectin_C PF00059.19 001309931.1_31522001_3 - 5.7e-15 55.9 1.8 1.3e-14 54.7 1.8 1.6 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.10 001309931.1_31522001_3 - 0.00083 18.9 3.3 0.0017 17.9 3.3 1.5 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001309931.1_31522001_3 - 0.0053 15.9 1.9 0.0099 15.0 1.9 1.6 1 1 0 1 1 1 1 Chordopoxvirus A33R protein Peptidase_M11 PF05548.9 001309931.1_31522001_3 - 0.044 12.8 0.1 0.056 12.5 0.1 1.2 1 0 0 1 1 1 0 Gametolysin peptidase M11 ig PF00047.23 001309950.1_31523001_2 - 2.2e-19 69.2 7.1 2.3e-06 27.5 0.2 3.6 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.4 001309950.1_31523001_2 - 5.8e-19 68.1 3.0 5.6e-06 26.5 0.1 4.1 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.4 001309950.1_31523001_2 - 2.1e-16 60.1 0.5 4.3e-05 23.9 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001309950.1_31523001_2 - 2.2e-06 27.6 5.6 1.7 8.7 0.0 5.6 4 2 2 6 6 6 2 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001309950.1_31523001_2 - 0.0068 16.3 0.2 1.2 9.1 0.0 3.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Glycogen_syn PF05693.11 001303551.2_08528001_1 - 0 1204.4 0.0 0 1204.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.4 001303551.2_08528001_1 - 7.6e-07 29.2 0.1 1.4e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.9 001303551.2_08528001_1 - 1.2e-05 25.0 0.3 2.5e-05 24.0 0.3 1.5 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 001303551.2_08528001_1 - 2.5e-05 23.8 0.1 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.4 001303551.2_08528001_1 - 4.5e-05 23.8 0.3 0.00011 22.5 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.4 001303551.2_08528001_1 - 0.00029 21.1 0.0 0.02 15.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Lectin_C PF00059.19 001309934.1_31522001_2 - 1e-16 61.5 2.2 1e-16 61.5 2.2 1.5 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.10 001309934.1_31522001_2 - 6.1e-07 29.1 0.7 1e-06 28.4 0.7 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Ly49 PF08391.8 001309934.1_31522001_2 - 0.0016 18.6 0.7 0.0016 18.6 0.7 2.3 1 1 1 2 2 2 1 Ly49-like protein, N-terminal region ANP PF00212.16 001303557.1_08522001_3 - 9.2e-14 51.2 8.9 9.2e-14 51.2 8.9 2.4 3 0 0 3 3 3 1 Atrial natriuretic peptide Pox_A_type_inc PF04508.10 001303557.1_08522001_3 - 0.18 11.6 1.0 0.38 10.6 1.0 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF4723 PF15851.3 001082084.1_37923001_1 - 1.3 9.1 9.4 1.9 8.6 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4723) Cys_knot PF00007.20 001280877.1_36321001_2 - 3.2e-32 110.8 7.7 3.7e-32 110.6 7.7 1.0 1 0 0 1 1 1 1 Cystine-knot domain adh_short PF00106.23 001244007.1_14223001_1 - 1.7e-36 125.4 0.0 4e-28 98.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.4 001244007.1_14223001_1 - 1.8e-28 99.6 0.0 1.1e-19 70.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001244007.1_14223001_1 - 4.4e-08 33.1 0.0 8.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001244007.1_14223001_1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.16 001244007.1_14223001_1 - 0.07 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain STAT_bind PF02864.13 001286592.1_40029001_2 - 2.3e-76 256.8 0.0 2.3e-76 256.8 0.0 1.9 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.18 001286592.1_40029001_2 - 1.1e-55 188.2 18.5 1.7e-55 187.5 18.5 1.3 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.15 001286592.1_40029001_2 - 1.4e-32 112.6 2.6 1.4e-32 112.6 2.6 2.9 3 1 1 4 4 4 1 STAT protein, protein interaction domain SH2 PF00017.22 001286592.1_40029001_2 - 3.9e-13 49.1 0.0 8.7e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain E2R135 PF11570.6 001286592.1_40029001_2 - 0.23 11.6 1.4 0.44 10.7 1.4 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 YojJ PF10372.7 001286592.1_40029001_2 - 1.2 9.2 7.1 2.3 8.2 0.4 2.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Syntaxin-6_N PF09177.9 001286592.1_40029001_2 - 1.3 9.5 6.7 0.19 12.2 0.6 2.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.8 001286592.1_40029001_2 - 3.1 7.8 12.4 1.2 9.1 7.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RecG_N PF17190.2 001286592.1_40029001_2 - 9 7.0 10.1 4 8.1 0.2 3.5 3 1 0 3 3 3 0 RecG N-terminal helical domain V-set PF07686.15 001009841.1_22424001_2 - 8.4e-08 32.2 0.0 2.6e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain C2-set PF05790.13 001009841.1_22424001_2 - 3.1e-05 23.9 1.6 6.7e-05 22.9 1.6 1.6 1 0 0 1 1 1 1 Immunoglobulin C2-set domain Ig_3 PF13927.4 001009841.1_22424001_2 - 0.0021 18.5 0.7 2.3 8.7 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001009841.1_22424001_2 - 0.0043 17.0 0.7 0.039 13.9 0.1 2.7 1 1 1 2 2 2 1 Immunoglobulin I-set domain Cadherin_C_2 PF16492.3 001009841.1_22424001_2 - 0.08 13.6 0.0 0.25 12.0 0.0 1.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal PspB PF06667.10 001009841.1_22424001_2 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein B YhzD PF14120.4 001009841.1_22424001_2 - 0.16 12.0 1.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 YhzD-like protein FAM176 PF14851.4 001009841.1_22424001_2 - 0.2 11.2 0.1 0.38 10.3 0.1 1.3 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.16 001290900.1_07323001_1 - 1.2e-116 390.1 7.9 1.2e-116 390.1 7.9 1.4 2 0 0 2 2 2 1 Myc amino-terminal region Myc-LZ PF02344.13 001290900.1_07323001_1 - 4.9e-16 58.4 10.4 4.9e-16 58.4 10.4 2.1 2 0 0 2 2 2 1 Myc leucine zipper domain HLH PF00010.24 001290900.1_07323001_1 - 2.4e-14 52.9 1.5 2.4e-14 52.9 1.5 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TFIIE-A_C PF11521.6 001290900.1_07323001_1 - 2 8.7 7.1 5.1 7.4 3.9 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha SRP-alpha_N PF04086.11 001290900.1_07323001_1 - 2.8 7.7 9.9 4.4 7.0 9.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Casein PF00363.16 001303519.1_08423001_1 - 6.1e-19 68.3 15.1 6.1e-19 68.3 15.1 3.2 2 1 1 3 3 3 1 Casein Chromo_shadow PF01393.17 001246702.1_14224001_1 - 1.7e-31 107.9 0.1 1.7e-28 98.3 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.22 001246702.1_14224001_1 - 5e-18 64.6 0.0 2.2e-15 56.1 0.1 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.4 001246702.1_14224001_1 - 0.036 14.1 0.1 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Hormone_1 PF00103.18 001287199.1_52722001_1 - 1.8e-56 191.1 0.1 2.5e-56 190.7 0.1 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Hormone_1 PF00103.18 001287199.1_52722001_3 - 4.2e-17 62.5 2.7 5.5e-17 62.1 2.7 1.1 1 0 0 1 1 1 1 Somatotropin hormone family V-set PF07686.15 001318342.1_52722001_1 - 2.6e-14 53.2 0.3 8.6e-14 51.5 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001318342.1_52722001_1 - 5.5e-07 30.0 0.2 4.4e-06 27.1 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.13 001318342.1_52722001_1 - 2.8e-06 27.6 0.2 2.8e-06 27.6 0.2 2.9 4 1 0 4 4 4 1 Immunoglobulin C1-set domain Ig_2 PF13895.4 001318342.1_52722001_1 - 8.1e-06 26.0 0.5 0.0072 16.5 0.1 3.0 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001318342.1_52722001_1 - 0.00016 21.5 0.0 0.00065 19.6 0.0 2.0 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.23 001318342.1_52722001_1 - 0.00022 21.2 0.4 0.004 17.2 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin domain ANP PF00212.16 001303555.1_08522001_3 - 4.4e-11 42.6 3.3 1e-10 41.5 3.3 1.6 1 0 0 1 1 1 1 Atrial natriuretic peptide Hormone_6 PF00236.16 001280865.1_36322001_2 - 3.3e-50 167.9 11.2 6.1e-50 167.0 11.2 1.5 1 0 0 1 1 1 1 Glycoprotein hormone p450 PF00067.20 001267751.1_08024001_2 - 1.3e-145 485.6 0.0 1.5e-145 485.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Casein_kappa PF00997.16 001303518.1_08422001_3 - 1.2e-71 239.8 20.6 1.4e-71 239.6 18.9 1.8 2 0 0 2 2 2 1 Kappa casein Histone PF00125.22 001282367.1_11322001_1 - 2.3e-53 180.0 1.9 2.7e-53 179.7 1.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001282367.1_11322001_1 - 0.00011 22.1 0.1 0.00021 21.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.4 001282367.1_11322001_1 - 0.00067 19.8 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.3 001282367.1_11322001_1 - 0.02 15.4 2.2 0.029 14.8 2.2 1.2 1 0 0 1 1 1 0 PCNA-associated factor WD40 PF00400.30 073602.1_43525120_3 - 3.5e-09 37.0 3.1 1.8 9.5 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 073602.1_43525120_3 - 0.00043 20.4 0.1 2.6 8.3 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TNF PF00229.16 001323335.1_21222001_1 - 5.8e-45 152.2 0.9 1e-44 151.4 0.9 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.19 001323335.1_21222001_1 - 0.059 13.5 1.3 0.56 10.3 0.1 2.4 1 1 1 2 2 2 0 C1q domain TNF PF00229.16 001205141.1_32322001_1 - 5.9e-14 52.0 0.0 1.4e-13 50.7 0.0 1.6 2 0 0 2 2 2 1 TNF(Tumour Necrosis Factor) family C1q PF00386.19 001205141.1_32322001_1 - 0.0075 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 C1q domain Porin_2 PF02530.12 001205141.1_32322001_1 - 0.13 11.4 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Porin subfamily Ald_Xan_dh_C2 PF02738.16 001309952.1_31529001_1 - 8.9e-188 625.0 0.0 1.2e-187 624.6 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001309952.1_31529001_1 - 4.5e-46 156.6 0.0 1.2e-45 155.2 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001309952.1_31529001_1 - 8.5e-33 112.9 0.2 1.6e-32 112.0 0.2 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001309952.1_31529001_1 - 1.1e-30 105.2 0.2 2.6e-30 104.1 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001309952.1_31529001_1 - 2.9e-29 101.1 0.1 1.6e-27 95.5 0.0 3.1 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001309952.1_31529001_1 - 9.6e-09 35.0 0.1 9.6e-09 35.0 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001309952.1_31529001_1 - 0.011 15.4 1.3 0.037 13.7 1.3 1.9 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B ODC_AZ PF02100.15 001289669.1_35723001_3 - 8e-20 70.8 0.0 1.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289801.1_37423001_3 - 4.7e-20 71.6 0.0 7.9e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289810.1_10723001_3 - 4.7e-20 71.6 0.0 8.6e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289825.1_36222001_2 - 2.3e-20 72.5 0.0 3.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme TYA PF01021.17 001289829.1_27022001_1 - 0.56 10.4 8.1 7.7 6.8 4.4 2.2 2 0 0 2 2 2 0 TYA transposon protein ODC_AZ PF02100.15 001289829.1_27022001_3 - 3.7e-21 75.1 0.0 6.2e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289835.1_13423001_3 - 1.2e-19 70.3 0.0 2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289870.1_31923001_3 - 6.3e-21 74.4 0.0 1.1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289871.1_11322001_1 - 3.8e-20 71.9 0.0 6.4e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289904.1_33424001_1 - 6.4e-20 71.1 0.0 1.2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289954.1_35724001_3 - 1e-19 70.4 0.0 1.7e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290019.1_37423001_3 - 2.8e-20 72.3 0.0 5.8e-20 71.3 0.0 1.4 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290029.1_36524001_1 - 6.7e-20 71.1 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290032.1_10725001_1 - 7.6e-20 70.9 0.0 1.4e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290034.1_16224001_3 - 1.1e-19 70.3 0.0 1.8e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290035.1_36224001_1 - 5.9e-20 71.3 0.0 9.5e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290037.1_27024001_1 - 3.8e-19 68.7 0.0 7.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290038.1_13424001_2 - 6.3e-20 71.2 0.0 1.2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290041.1_20323001_2 - 6.6e-20 71.1 0.0 1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290102.1_31924001_3 - 1e-19 70.5 0.0 1.7e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290103.1_11324001_1 - 4.4e-20 71.7 0.0 8.7e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290136.1_06424001_2 - 6.6e-20 71.1 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290147.1_52124001_2 - 5.1e-20 71.5 0.0 1.1e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290156.1_52724001_1 - 1.2e-19 70.2 0.0 2.4e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290195.1_28323001_2 - 1.7e-19 69.8 0.0 2.8e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290198.1_20624001_2 - 6.2e-20 71.2 0.0 1.2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290197.1_12124001_2 - 4.3e-20 71.7 0.0 8.1e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290203.1_12122001_2 - 5.1e-21 74.7 0.0 8.6e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290275.1_35722001_1 - 1.3e-14 54.0 0.0 1.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290373.1_37422001_1 - 1.6e-15 57.0 0.0 2.2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290386.1_51322001_2 - 4.9e-14 52.2 0.0 6.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290394.1_36522001_3 - 2e-15 56.6 0.0 2.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290396.1_10722001_3 - 2.6e-15 56.3 0.0 3.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290400.1_16222001_1 - 5.6e-14 52.0 0.0 8.8e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290401.1_36222001_1 - 4.2e-14 52.4 0.0 6.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290408.1_48822001_3 - 4.7e-15 55.4 0.0 6.8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290450.1_27022001_1 - 2.8e-14 52.9 0.0 5.8e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290456.1_13422001_1 - 4.3e-15 55.6 0.0 6.2e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290458.1_20322001_1 - 2.1e-15 56.6 0.0 3.1e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290471.1_33422001_3 - 1.2e-15 57.3 0.0 1.7e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290494.1_26722001_3 - 1.4e-14 54.0 0.0 2.1e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290499.1_31922001_2 - 2.4e-16 59.6 0.0 3.5e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290507.1_11322001_3 - 1.1e-14 54.2 0.0 1.8e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Cu-oxidase_3 PF07732.13 001290507.1_11322001_3 - 0.019 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase ODC_AZ PF02100.15 001290531.1_33622001_1 - 9.5e-15 54.5 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Cu-oxidase_3 PF07732.13 001290531.1_33622001_1 - 0.027 14.4 0.0 0.067 13.1 0.0 1.5 1 1 0 1 1 1 0 Multicopper oxidase ODC_AZ PF02100.15 001290534.1_06422001_1 - 7.2e-13 48.4 0.0 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290538.1_40022001_1 - 4.9e-15 55.4 0.0 6.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290632.1_52122001_2 - 3e-16 59.3 0.0 4.3e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Cu-oxidase_3 PF07732.13 001290632.1_52122001_2 - 0.17 11.8 0.2 0.43 10.5 0.0 1.6 1 1 0 2 2 2 0 Multicopper oxidase ODC_AZ PF02100.15 001290638.1_08622001_1 - 9.3e-15 54.5 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290647.1_52722001_1 - 4.2e-15 55.6 0.0 5.8e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290653.1_33722001_1 - 9.5e-15 54.5 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Cu-oxidase_3 PF07732.13 001290653.1_33722001_1 - 0.027 14.3 0.0 0.067 13.1 0.0 1.5 1 1 0 1 1 1 0 Multicopper oxidase ODC_AZ PF02100.15 001290650.1_28322001_3 - 2e-15 56.6 0.0 3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290657.1_12122001_2 - 1.2e-16 60.6 0.0 1.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290663.1_44822001_3 - 2.4e-15 56.4 0.0 3.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290668.1_41222001_1 - 1.5e-16 60.3 0.0 2.2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290748.1_42222001_1 - 1.6e-14 53.8 0.0 2.2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290754.1_05122001_1 - 1.8e-15 56.8 0.0 2.5e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Asp_protease_2 PF13650.4 001291072.1_40429001_2 - 0.00079 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291072.1_40429001_2 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291072.1_40429001_2 - 0.053 14.0 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291072.1_40429001_3 - 4.8e-15 55.5 1.9 1.9e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291072.1_40429001_3 - 5.1e-15 55.2 0.0 9.4e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291072.1_40429001_3 - 0.00034 20.6 0.1 0.00067 19.7 0.1 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291072.1_40429001_3 - 0.0021 17.8 4.6 0.0035 17.1 4.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291072.1_40429001_3 - 0.0029 17.1 0.2 0.0069 15.9 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291072.1_40429001_3 - 0.0078 15.9 0.5 0.013 15.2 0.5 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 SlyX PF04102.10 001291072.1_40429001_3 - 0.3 11.6 2.4 0.71 10.4 2.4 1.7 1 0 0 1 1 1 0 SlyX CENP-H PF05837.10 001291072.1_40429001_3 - 0.41 10.9 4.7 0.85 9.9 4.7 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.10 001291072.1_40429001_3 - 0.59 10.5 9.7 1.4 9.3 9.7 1.6 1 0 0 1 1 1 0 Cell division protein ZapB CCDC106 PF15794.3 001291072.1_40429001_3 - 0.67 9.5 3.6 0.86 9.1 2.3 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF972 PF06156.11 001291072.1_40429001_3 - 0.76 10.3 3.9 2 9.0 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.12 001291072.1_40429001_3 - 1.1 8.8 3.4 2.3 7.8 3.4 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.13 001291072.1_40429001_3 - 3.6 7.3 7.1 8.7 6.1 7.1 1.6 1 0 0 1 1 1 0 Septum formation initiator SHE3 PF17078.3 001291072.1_40429001_3 - 8.2 5.9 10.2 2.2 7.8 7.1 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Asp_protease_2 PF13650.4 001291086.1_46729001_2 - 0.00072 20.1 0.0 0.0012 19.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291086.1_46729001_2 - 0.015 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291086.1_46729001_2 - 0.048 14.1 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291086.1_46729001_3 - 4e-15 55.8 2.1 1.7e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291086.1_46729001_3 - 4.8e-15 55.3 0.0 8.2e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291086.1_46729001_3 - 0.00018 21.5 0.1 0.0003 20.8 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291086.1_46729001_3 - 0.002 17.9 5.0 0.0033 17.2 5.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291086.1_46729001_3 - 0.0028 17.2 0.2 0.0065 16.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291086.1_46729001_3 - 0.0044 16.8 0.5 0.0076 16.0 0.5 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF1664 PF07889.10 001291086.1_46729001_3 - 0.2 11.5 1.0 0.4 10.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.9 001291086.1_46729001_3 - 0.22 10.2 3.6 0.39 9.4 3.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.10 001291086.1_46729001_3 - 0.24 11.7 4.9 0.48 10.7 4.9 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001291086.1_46729001_3 - 0.28 11.7 3.9 0.69 10.4 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291086.1_46729001_3 - 0.36 11.2 9.9 0.83 10.0 9.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB TolA_bind_tri PF16331.3 001291086.1_46729001_3 - 0.45 10.5 4.4 0.85 9.6 4.4 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation SlyX PF04102.10 001291086.1_46729001_3 - 0.53 10.8 2.8 1.3 9.5 2.8 1.7 1 0 0 1 1 1 0 SlyX IncA PF04156.12 001291086.1_46729001_3 - 0.63 9.7 4.5 1.3 8.7 4.5 1.4 1 0 0 1 1 1 0 IncA protein bZIP_1 PF00170.19 001291086.1_46729001_3 - 0.77 9.8 6.5 2 8.5 6.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor TMF_DNA_bd PF12329.6 001291086.1_46729001_3 - 0.92 9.4 6.5 1.9 8.4 6.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.13 001291086.1_46729001_3 - 2.8 7.6 6.8 6.5 6.5 6.8 1.5 1 0 0 1 1 1 0 Septum formation initiator CCDC106 PF15794.3 001291086.1_46729001_3 - 4.5 6.8 6.9 0.5 9.9 2.5 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 GIT_CC PF16559.3 001291086.1_46729001_3 - 4.7 7.2 7.9 13 5.8 8.0 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SHE3 PF17078.3 001291086.1_46729001_3 - 6.6 6.2 10.8 1.7 8.1 7.8 1.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Asp_protease_2 PF13650.4 001291095.1_35729001_2 - 0.00077 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291095.1_35729001_2 - 0.011 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291095.1_35729001_2 - 0.051 14.0 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291095.1_35729001_3 - 5e-15 55.2 0.0 9.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291095.1_35729001_3 - 1.2e-14 54.3 1.9 5e-14 52.2 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001291095.1_35729001_3 - 0.00034 20.6 0.1 0.00065 19.7 0.1 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291095.1_35729001_3 - 0.0019 17.9 4.7 0.0033 17.2 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291095.1_35729001_3 - 0.0029 17.1 0.2 0.0064 16.0 0.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291095.1_35729001_3 - 0.0066 16.2 0.4 0.011 15.5 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 ZapB PF06005.10 001291095.1_35729001_3 - 0.23 11.8 9.2 0.68 10.3 9.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapB CENP-H PF05837.10 001291095.1_35729001_3 - 0.25 11.6 5.4 0.47 10.8 4.8 1.7 2 0 0 2 2 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001291095.1_35729001_3 - 0.32 11.5 3.8 0.79 10.3 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CCDC106 PF15794.3 001291095.1_35729001_3 - 0.36 10.4 4.1 0.55 9.8 2.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Spc7 PF08317.9 001291095.1_35729001_3 - 0.37 9.5 3.4 0.65 8.7 3.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.3 001291095.1_35729001_3 - 0.4 10.9 3.9 0.68 10.2 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) SlyX PF04102.10 001291095.1_35729001_3 - 0.49 10.9 2.6 1.4 9.4 2.6 1.8 1 0 0 1 1 1 0 SlyX LPP PF04728.11 001291095.1_35729001_3 - 0.66 10.3 2.1 1.3 9.4 2.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper SHE3 PF17078.3 001291095.1_35729001_3 - 0.73 9.4 7.3 1.6 8.3 7.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001291095.1_35729001_3 - 1.1 9.0 5.9 2.3 7.9 5.9 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001291095.1_35729001_3 - 1.3 9.0 8.4 3.3 7.7 8.4 1.7 1 0 0 1 1 1 0 bZIP transcription factor TMF_DNA_bd PF12329.6 001291095.1_35729001_3 - 1.5 8.7 6.5 3.8 7.4 6.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.12 001291095.1_35729001_3 - 1.6 8.3 5.3 3.2 7.4 5.3 1.4 1 0 0 1 1 1 0 IncA protein GIT_CC PF16559.3 001291095.1_35729001_3 - 1.8 8.5 7.1 5.2 7.0 7.1 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291095.1_35729001_3 - 5.5 7.2 7.5 39 4.5 7.5 2.3 1 1 0 1 1 1 0 TSC-22/dip/bun family Asp_protease_2 PF13650.4 001291097.1_37429001_1 - 0.00033 21.1 0.0 0.00057 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291097.1_37429001_1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291097.1_37429001_1 - 0.048 14.1 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CAP_N PF01213.17 001291097.1_37429001_1 - 6.8 5.9 10.7 14 4.9 10.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Retrotrans_gag PF03732.15 001291097.1_37429001_2 - 3.1e-15 56.1 3.5 6.6e-15 55.1 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291097.1_37429001_2 - 2.4e-14 53.0 0.0 4.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291097.1_37429001_2 - 0.00029 20.6 5.0 0.00051 19.8 5.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291097.1_37429001_2 - 0.0021 17.6 0.2 0.0049 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger IncA PF04156.12 001291097.1_37429001_2 - 0.0091 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 IncA protein Rootletin PF15035.4 001291097.1_37429001_2 - 0.05 13.5 8.0 0.09 12.7 8.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CCDC106 PF15794.3 001291097.1_37429001_2 - 0.084 12.4 1.4 0.19 11.2 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 zf-CCHC PF00098.21 001291097.1_37429001_2 - 0.09 12.8 2.2 0.35 10.9 2.2 2.1 1 0 0 1 1 1 0 Zinc knuckle DUF1664 PF07889.10 001291097.1_37429001_2 - 0.24 11.2 0.6 0.43 10.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.3 001291097.1_37429001_2 - 0.31 11.0 4.3 0.69 9.9 4.3 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation SHE3 PF17078.3 001291097.1_37429001_2 - 0.34 10.4 6.8 0.72 9.4 6.8 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CENP-H PF05837.10 001291097.1_37429001_2 - 0.35 11.2 3.7 0.83 9.9 3.7 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001291097.1_37429001_2 - 0.38 11.3 3.9 0.88 10.1 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001291097.1_37429001_2 - 0.81 8.4 7.0 1.4 7.6 7.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.10 001291097.1_37429001_2 - 0.84 10.0 10.4 2 8.8 10.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.13 001291097.1_37429001_2 - 1.4 8.6 5.9 3.7 7.2 5.9 1.7 1 0 0 1 1 1 0 Septum formation initiator Mito_fiss_reg PF05308.9 001291097.1_37429001_2 - 1.7 8.5 5.4 3.2 7.6 5.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3450 PF11932.6 001291097.1_37429001_2 - 2 7.5 5.8 3.6 6.7 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.19 001291097.1_37429001_2 - 2.1 8.4 9.7 5.6 7.0 9.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor SlyX PF04102.10 001291097.1_37429001_2 - 2.4 8.7 5.8 5.9 7.5 5.8 1.6 1 0 0 1 1 1 0 SlyX APG6 PF04111.10 001291097.1_37429001_2 - 3.9 6.6 6.0 7.2 5.8 6.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GIT_CC PF16559.3 001291097.1_37429001_2 - 4 7.4 8.2 10 6.1 8.2 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CAP_N PF01213.17 001291097.1_37429001_2 - 8.9 5.5 8.0 16 4.7 8.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4939 PF16297.3 001291102.1_51329001_1 - 7e-15 54.8 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291102.1_51329001_1 - 5e-14 52.2 2.9 1.4e-13 50.8 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001291102.1_51329001_1 - 0.00039 20.4 0.5 0.00078 19.4 0.1 1.6 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291102.1_51329001_1 - 0.001 18.8 5.6 0.0017 18.1 5.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291102.1_51329001_1 - 0.0062 16.1 0.2 0.014 15.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291102.1_51329001_1 - 0.039 13.7 0.5 0.063 13.0 0.5 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF737 PF05300.9 001291102.1_51329001_1 - 0.11 12.7 3.5 0.19 11.9 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ZapB PF06005.10 001291102.1_51329001_1 - 0.12 12.7 8.2 0.3 11.4 8.2 1.6 1 0 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.10 001291102.1_51329001_1 - 0.14 12.7 1.6 0.32 11.5 1.6 1.6 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291102.1_51329001_1 - 0.18 11.0 6.1 0.31 10.2 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.12 001291102.1_51329001_1 - 0.24 11.0 4.5 0.44 10.2 4.5 1.3 1 0 0 1 1 1 0 IncA protein SHE3 PF17078.3 001291102.1_51329001_1 - 0.3 10.6 5.6 0.62 9.6 5.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.3 001291102.1_51329001_1 - 0.3 11.0 4.3 0.56 10.2 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Uso1_p115_C PF04871.11 001291102.1_51329001_1 - 0.38 11.0 6.3 0.64 10.3 6.3 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF972 PF06156.11 001291102.1_51329001_1 - 0.51 10.8 3.7 1.2 9.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.13 001291102.1_51329001_1 - 0.97 9.1 4.6 2.4 7.9 4.6 1.6 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.9 001291102.1_51329001_1 - 1 8.1 5.9 1.7 7.3 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.10 001291102.1_51329001_1 - 1.2 9.5 4.9 2.4 8.4 4.9 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.6 001291102.1_51329001_1 - 1.6 8.6 8.6 3.1 7.7 8.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.3 001291102.1_51329001_1 - 3.6 7.6 7.4 9.4 6.2 7.4 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Asp_protease_2 PF13650.4 001291102.1_51329001_3 - 0.00038 21.0 0.0 0.0006 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291102.1_51329001_3 - 0.041 13.7 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291102.1_51329001_3 - 0.068 13.6 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291109.1_36527001_1 - 7.1e-16 58.1 2.7 5.1e-15 55.4 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291109.1_36527001_1 - 3e-15 55.9 0.0 5.6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291109.1_36527001_1 - 3.3e-05 23.9 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291109.1_36527001_1 - 0.00025 20.8 4.3 0.00044 20.0 4.3 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291109.1_36527001_1 - 0.0011 18.5 0.2 0.0024 17.4 0.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CASP_C PF08172.10 001291109.1_36527001_1 - 0.0011 18.2 0.1 0.0018 17.5 0.1 1.2 1 0 0 1 1 1 1 CASP C terminal SR-25 PF10500.7 001291109.1_36527001_1 - 0.0074 15.8 6.4 0.0074 15.8 6.4 2.8 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein CENP-H PF05837.10 001291109.1_36527001_1 - 0.049 13.9 4.3 0.13 12.5 4.3 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-CCHC PF00098.21 001291109.1_36527001_1 - 0.053 13.5 2.2 0.17 11.9 2.2 2.0 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_C PF04871.11 001291109.1_36527001_1 - 0.066 13.4 3.8 0.11 12.8 3.8 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SHE3 PF17078.3 001291109.1_36527001_1 - 0.073 12.6 5.3 0.048 13.2 3.4 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ZapB PF06005.10 001291109.1_36527001_1 - 0.082 13.2 8.3 0.22 11.9 8.3 1.6 1 0 0 1 1 1 0 Cell division protein ZapB eIF3g PF12353.6 001291109.1_36527001_1 - 0.11 12.8 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Spc7 PF08317.9 001291109.1_36527001_1 - 0.11 11.2 4.4 0.22 10.2 4.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291109.1_36527001_1 - 0.13 12.7 3.4 0.39 11.2 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.17 001291109.1_36527001_1 - 0.14 9.9 0.4 0.2 9.3 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.10 001291109.1_36527001_1 - 0.15 12.0 0.6 0.3 10.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.6 001291109.1_36527001_1 - 0.16 11.9 5.5 0.33 10.8 5.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TolA_bind_tri PF16331.3 001291109.1_36527001_1 - 0.22 11.5 4.9 0.48 10.4 4.9 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation IncA PF04156.12 001291109.1_36527001_1 - 0.34 10.5 8.0 0.65 9.6 8.0 1.4 1 0 0 1 1 1 0 IncA protein Prominin PF05478.9 001291109.1_36527001_1 - 0.36 8.6 1.0 0.56 8.0 1.0 1.1 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.6 001291109.1_36527001_1 - 0.48 9.5 5.4 0.83 8.8 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.10 001291109.1_36527001_1 - 0.8 10.2 5.2 2.6 8.6 5.2 1.8 1 0 0 1 1 1 0 SlyX GIT_CC PF16559.3 001291109.1_36527001_1 - 1.9 8.4 8.3 5.7 6.9 8.3 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.4 001291109.1_36527001_1 - 3.6 7.5 10.0 12 5.9 9.9 1.7 1 1 0 1 1 1 0 FlxA-like protein TSC22 PF01166.16 001291109.1_36527001_1 - 8 6.7 7.5 43 4.4 7.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family APG6 PF04111.10 001291109.1_36527001_1 - 10 5.3 7.3 2.2 7.4 4.0 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Asp_protease_2 PF13650.4 001291109.1_36527001_3 - 0.0002 21.8 0.0 0.00034 21.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291109.1_36527001_3 - 0.0049 16.7 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291109.1_36527001_3 - 0.022 15.2 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001291112.1_10729001_1 - 0.00077 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291112.1_10729001_1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291112.1_10729001_1 - 0.051 14.0 0.0 0.087 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291112.1_10729001_2 - 3.1e-15 56.1 2.6 1.2e-14 54.2 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291112.1_10729001_2 - 4.9e-15 55.2 0.0 9e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291112.1_10729001_2 - 0.00015 21.8 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291112.1_10729001_2 - 0.00021 21.1 2.3 0.00044 20.0 2.3 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291112.1_10729001_2 - 0.0019 17.7 0.2 0.005 16.4 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CASP_C PF08172.10 001291112.1_10729001_2 - 0.017 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 CASP C terminal SHE3 PF17078.3 001291112.1_10729001_2 - 0.042 13.4 3.1 0.086 12.4 3.1 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Spc29 PF17082.3 001291112.1_10729001_2 - 0.043 13.5 0.8 0.07 12.8 0.8 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Uso1_p115_C PF04871.11 001291112.1_10729001_2 - 0.062 13.5 2.2 0.11 12.8 2.2 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.6 001291112.1_10729001_2 - 0.086 12.0 1.2 0.14 11.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.10 001291112.1_10729001_2 - 0.11 12.8 7.6 0.26 11.6 7.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291112.1_10729001_2 - 0.2 12.2 2.3 0.49 10.9 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TolA_bind_tri PF16331.3 001291112.1_10729001_2 - 0.24 11.3 4.2 0.5 10.3 4.2 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation IncA PF04156.12 001291112.1_10729001_2 - 0.25 11.0 4.9 0.47 10.1 4.9 1.4 1 0 0 1 1 1 0 IncA protein zf-CCHC PF00098.21 001291112.1_10729001_2 - 0.3 11.1 5.0 0.36 10.9 2.2 2.6 2 0 0 2 2 2 0 Zinc knuckle Spc7 PF08317.9 001291112.1_10729001_2 - 0.32 9.7 3.7 0.56 8.9 3.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.6 001291112.1_10729001_2 - 0.78 9.6 6.8 1.6 8.6 6.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.13 001291112.1_10729001_2 - 1.1 8.9 5.2 2.8 7.6 5.2 1.7 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.10 001291112.1_10729001_2 - 1.4 9.4 4.9 3.6 8.1 4.9 1.6 1 0 0 1 1 1 0 SlyX RCDG1 PF15725.3 001291112.1_10729001_2 - 1.6 9.1 8.3 3.8 7.9 8.3 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein GIT_CC PF16559.3 001291112.1_10729001_2 - 3.4 7.6 7.3 8.6 6.3 7.3 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.19 001291112.1_10729001_2 - 3.5 7.7 8.3 14 5.7 8.3 2.0 1 1 1 2 2 2 0 bZIP transcription factor CENP-H PF05837.10 001291112.1_10729001_2 - 4.9 7.5 10.0 0.87 9.9 4.1 2.4 3 0 0 3 3 2 0 Centromere protein H (CENP-H) CAP_N PF01213.17 001291112.1_10729001_2 - 8.6 5.6 12.1 16 4.7 12.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4939 PF16297.3 001291116.1_16229001_1 - 1.1e-15 57.3 0.0 2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291116.1_16229001_1 - 3.7e-15 55.9 3.4 5.2e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein KASH_CCD PF14662.4 001291116.1_16229001_1 - 0.00087 19.1 6.0 0.0014 18.4 6.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291116.1_16229001_1 - 0.0058 16.2 0.2 0.014 15.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CCDC106 PF15794.3 001291116.1_16229001_1 - 0.056 13.0 0.5 0.091 12.3 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ZapB PF06005.10 001291116.1_16229001_1 - 0.25 11.7 9.1 0.59 10.5 9.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291116.1_16229001_1 - 0.33 11.5 4.0 0.77 10.3 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Rootletin PF15035.4 001291116.1_16229001_1 - 0.35 10.8 9.2 0.6 10.0 9.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.10 001291116.1_16229001_1 - 0.43 10.9 6.2 0.91 9.8 6.2 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SHE3 PF17078.3 001291116.1_16229001_1 - 0.43 10.1 5.6 0.81 9.2 5.6 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TBPIP PF07106.11 001291116.1_16229001_1 - 0.68 9.5 5.1 1.3 8.6 5.1 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.9 001291116.1_16229001_1 - 1 8.0 6.6 1.7 7.3 6.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.6 001291116.1_16229001_1 - 1.2 9.0 8.5 2.3 8.2 8.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.3 001291116.1_16229001_1 - 1.4 8.8 6.5 3.7 7.5 6.5 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.19 001291116.1_16229001_1 - 1.6 8.7 7.2 3.6 7.6 7.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.13 001291116.1_16229001_1 - 2 8.1 6.0 5 6.8 6.0 1.7 1 0 0 1 1 1 0 Septum formation initiator Uso1_p115_C PF04871.11 001291116.1_16229001_1 - 2.2 8.5 9.7 3.7 7.8 9.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.16 001291116.1_16229001_1 - 2.4 8.3 6.2 5.2 7.2 1.6 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper CAP_N PF01213.17 001291116.1_16229001_1 - 3.3 7.0 5.3 6.4 6.0 5.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SlyX PF04102.10 001291116.1_16229001_1 - 3.4 8.2 5.8 8.9 6.9 5.8 1.6 1 0 0 1 1 1 0 SlyX IncA PF04156.12 001291116.1_16229001_1 - 4.7 6.8 8.8 11 5.6 8.8 1.6 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.6 001291116.1_16229001_1 - 6.4 5.9 6.3 10 5.2 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Asp_protease_2 PF13650.4 001291116.1_16229001_3 - 0.00034 21.1 0.0 0.00056 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291116.1_16229001_3 - 0.0034 17.2 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291116.1_16229001_3 - 0.026 15.0 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001291139.1_48829001_2 - 0.00031 21.2 0.0 0.00051 20.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291139.1_48829001_2 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291139.1_48829001_2 - 0.033 14.6 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291139.1_48829001_3 - 1.3e-15 57.3 5.4 3.1e-15 56.1 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291139.1_48829001_3 - 5.9e-15 55.0 0.0 2e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) ATG16 PF08614.9 001291139.1_48829001_3 - 2.2e-05 24.6 0.8 3.7e-05 23.9 0.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Rootletin PF15035.4 001291139.1_48829001_3 - 8.5e-05 22.6 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291139.1_48829001_3 - 0.0002 21.2 5.1 0.00033 20.4 5.1 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291139.1_48829001_3 - 0.0011 18.5 0.2 0.0034 16.9 0.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger SR-25 PF10500.7 001291139.1_48829001_3 - 0.0088 15.5 10.4 0.018 14.5 10.4 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3450 PF11932.6 001291139.1_48829001_3 - 0.016 14.4 4.9 0.028 13.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uso1_p115_C PF04871.11 001291139.1_48829001_3 - 0.045 14.0 4.0 0.077 13.2 4.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF5082 PF16888.3 001291139.1_48829001_3 - 0.057 13.6 4.6 0.28 11.4 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF737 PF05300.9 001291139.1_48829001_3 - 0.062 13.5 4.1 0.11 12.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CENP-H PF05837.10 001291139.1_48829001_3 - 0.063 13.6 3.5 0.14 12.5 3.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.10 001291139.1_48829001_3 - 0.094 13.0 8.6 0.21 11.9 8.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB IncA PF04156.12 001291139.1_48829001_3 - 0.11 12.2 10.9 0.21 11.2 10.9 1.4 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.10 001291139.1_48829001_3 - 0.14 12.0 1.8 0.28 11.1 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-CCHC PF00098.21 001291139.1_48829001_3 - 0.16 12.0 7.1 0.24 11.4 2.2 3.1 2 0 0 2 2 2 0 Zinc knuckle DUF972 PF06156.11 001291139.1_48829001_3 - 0.17 12.4 4.0 0.43 11.1 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.10 001291139.1_48829001_3 - 0.17 11.1 3.1 0.28 10.4 3.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.9 001291139.1_48829001_3 - 0.41 9.3 5.3 0.75 8.5 5.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.10 001291139.1_48829001_3 - 0.64 8.0 6.3 0.92 7.4 6.3 1.1 1 0 0 1 1 1 0 HOOK protein TMF_DNA_bd PF12329.6 001291139.1_48829001_3 - 0.8 9.6 8.2 1.6 8.7 8.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.10 001291139.1_48829001_3 - 0.82 10.2 5.4 2.3 8.8 5.4 1.7 1 0 0 1 1 1 0 SlyX bZIP_1 PF00170.19 001291139.1_48829001_3 - 0.83 9.7 8.1 2 8.5 4.0 2.2 1 1 0 1 1 1 0 bZIP transcription factor FlxA PF14282.4 001291139.1_48829001_3 - 0.86 9.5 13.8 2.5 8.0 13.8 1.7 1 1 0 1 1 1 0 FlxA-like protein APG6 PF04111.10 001291139.1_48829001_3 - 1.9 7.7 6.0 3.6 6.7 6.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.16 001291139.1_48829001_3 - 2.1 8.5 8.6 8 6.6 2.2 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper SHE3 PF17078.3 001291139.1_48829001_3 - 2.3 7.8 8.5 0.91 9.1 6.0 1.5 2 0 0 2 2 1 0 SWI5-dependent HO expression protein 3 Mnd1 PF03962.13 001291139.1_48829001_3 - 2.7 7.7 5.9 5.7 6.6 5.9 1.4 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.13 001291139.1_48829001_3 - 4.1 7.1 11.2 15 5.3 0.9 2.5 1 1 1 2 2 2 0 Septum formation initiator GIT_CC PF16559.3 001291139.1_48829001_3 - 5 7.1 10.2 21 5.1 9.8 2.1 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Asp_protease_2 PF13650.4 001291180.1_27029001_1 - 0.0093 16.5 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291180.1_27029001_1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.15 001291180.1_27029001_2 - 3e-16 59.3 0.1 3e-16 59.3 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291180.1_27029001_2 - 4.2e-15 55.5 0.0 7.4e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001291180.1_27029001_2 - 0.0016 18.0 0.2 0.004 16.7 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001291180.1_27029001_2 - 0.0024 17.6 3.5 0.004 16.9 3.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH IncA PF04156.12 001291180.1_27029001_2 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 IncA protein Spc29 PF17082.3 001291180.1_27029001_2 - 0.048 13.4 0.2 0.081 12.6 0.2 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 TolA_bind_tri PF16331.3 001291180.1_27029001_2 - 0.095 12.7 2.6 0.19 11.7 2.6 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Rootletin PF15035.4 001291180.1_27029001_2 - 0.1 12.5 7.1 0.2 11.6 7.1 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ERM PF00769.17 001291180.1_27029001_2 - 0.14 11.8 4.6 0.25 11.0 4.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ZapB PF06005.10 001291180.1_27029001_2 - 0.15 12.4 8.0 0.32 11.3 8.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291180.1_27029001_2 - 0.48 11.0 3.0 1.4 9.5 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) SlyX PF04102.10 001291180.1_27029001_2 - 0.51 10.9 4.7 1.4 9.4 4.7 1.7 1 0 0 1 1 1 0 SlyX CCDC106 PF15794.3 001291180.1_27029001_2 - 0.52 9.9 2.3 0.9 9.1 2.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 bZIP_1 PF00170.19 001291180.1_27029001_2 - 1.1 9.3 6.5 2.5 8.2 6.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor zf-CCHC PF00098.21 001291180.1_27029001_2 - 1.3 9.0 7.1 0.31 11.1 2.2 2.5 2 0 0 2 2 2 0 Zinc knuckle GIT_CC PF16559.3 001291180.1_27029001_2 - 2.4 8.1 6.2 8.4 6.4 6.2 1.9 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291180.1_27029001_2 - 4.2 7.6 5.9 11 6.3 5.6 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family CENP-H PF05837.10 001291180.1_27029001_2 - 7.3 6.9 9.9 0.35 11.2 4.1 1.7 2 0 0 2 2 1 0 Centromere protein H (CENP-H) DUF4939 PF16297.3 001291193.1_20328001_1 - 6.8e-15 54.8 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291193.1_20328001_1 - 8.2e-14 51.5 2.7 1.9e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein KASH_CCD PF14662.4 001291193.1_20328001_1 - 0.01 15.5 6.2 0.017 14.8 6.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.10 001291193.1_20328001_1 - 0.019 15.3 8.2 0.046 14.0 8.2 1.6 1 0 0 1 1 1 0 Cell division protein ZapB CCDC106 PF15794.3 001291193.1_20328001_1 - 0.03 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Rootletin PF15035.4 001291193.1_20328001_1 - 0.038 13.9 6.2 0.07 13.1 6.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.10 001291193.1_20328001_1 - 0.048 13.5 0.5 0.097 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.11 001291193.1_20328001_1 - 0.093 13.2 3.8 0.24 11.9 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.19 001291193.1_20328001_1 - 0.11 12.5 6.9 0.33 11.0 6.9 1.8 1 0 0 1 1 1 0 bZIP transcription factor Dynactin_p22 PF07426.9 001291193.1_20328001_1 - 0.14 11.9 2.4 0.27 11.0 2.4 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 Spc7 PF08317.9 001291193.1_20328001_1 - 0.15 10.7 2.4 0.28 9.9 2.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF737 PF05300.9 001291193.1_20328001_1 - 0.2 11.9 3.1 0.42 10.8 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF737) SlyX PF04102.10 001291193.1_20328001_1 - 0.43 11.1 2.9 1.6 9.2 2.9 2.0 1 0 0 1 1 1 0 SlyX DUF3138 PF11336.6 001291193.1_20328001_1 - 0.6 8.5 1.8 0.89 8.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) IncA PF04156.12 001291193.1_20328001_1 - 0.68 9.6 4.2 1.2 8.7 4.2 1.3 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.6 001291193.1_20328001_1 - 0.94 8.6 3.6 1.6 7.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.13 001291193.1_20328001_1 - 4.1 7.1 10.1 0.35 10.6 5.4 1.6 2 0 0 2 2 1 0 Septum formation initiator GIT_CC PF16559.3 001291193.1_20328001_1 - 4.4 7.3 7.6 11 6.1 7.6 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291193.1_20328001_1 - 4.6 7.5 9.3 51 4.2 9.3 2.2 1 1 0 1 1 1 0 TSC-22/dip/bun family Asp_protease_2 PF13650.4 001291193.1_20328001_3 - 0.00021 21.8 0.0 0.00037 21.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.4 001291193.1_20328001_3 - 0.023 15.1 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.9 001291193.1_20328001_3 - 0.041 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.4 001291187.1_13429001_1 - 0.00048 20.6 0.0 0.00078 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291187.1_13429001_1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291187.1_13429001_1 - 0.05 14.0 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291187.1_13429001_2 - 2.8e-15 56.2 3.8 4.8e-15 55.5 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291187.1_13429001_2 - 6.9e-15 54.8 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291187.1_13429001_2 - 0.00065 19.5 4.5 0.0014 18.4 4.5 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291187.1_13429001_2 - 0.0018 17.8 0.2 0.005 16.4 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291187.1_13429001_2 - 0.0053 16.7 4.3 0.0099 15.8 4.3 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF737 PF05300.9 001291187.1_13429001_2 - 0.025 14.8 1.8 0.045 14.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CENP-H PF05837.10 001291187.1_13429001_2 - 0.081 13.2 3.7 0.19 12.0 3.7 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-CCHC PF00098.21 001291187.1_13429001_2 - 0.086 12.8 2.2 0.36 10.9 2.2 2.2 1 0 0 1 1 1 0 Zinc knuckle bZIP_1 PF00170.19 001291187.1_13429001_2 - 0.1 12.6 4.4 0.26 11.3 4.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 001291187.1_13429001_2 - 0.17 11.5 4.8 0.32 10.6 4.8 1.3 1 0 0 1 1 1 0 IncA protein TolA_bind_tri PF16331.3 001291187.1_13429001_2 - 0.37 10.8 4.3 0.71 9.9 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation ZapB PF06005.10 001291187.1_13429001_2 - 0.41 11.0 9.3 0.96 9.8 9.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB SHE3 PF17078.3 001291187.1_13429001_2 - 0.45 10.1 6.4 0.93 9.0 6.4 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001291187.1_13429001_2 - 0.54 9.9 4.1 1.4 8.6 4.1 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.11 001291187.1_13429001_2 - 0.61 10.6 4.1 1.4 9.5 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001291187.1_13429001_2 - 0.62 8.8 5.9 1.1 8.0 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.6 001291187.1_13429001_2 - 1.1 9.1 7.3 2.5 8.0 7.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.3 001291187.1_13429001_2 - 1.9 8.5 6.9 4.3 7.3 6.9 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Retrotrans_gag PF03732.15 001291198.1_33429001_1 - 6.7e-15 55.0 3.4 1.2e-14 54.2 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291198.1_33429001_1 - 6.9e-15 54.8 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291198.1_33429001_1 - 0.00014 21.9 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291198.1_33429001_1 - 0.00044 20.0 4.1 0.00072 19.3 4.1 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH CASP_C PF08172.10 001291198.1_33429001_1 - 0.0028 16.9 0.1 0.0043 16.3 0.1 1.2 1 0 0 1 1 1 1 CASP C terminal zf-CCHC_5 PF14787.4 001291198.1_33429001_1 - 0.005 16.4 0.2 0.005 16.4 0.2 2.2 2 0 0 2 2 1 1 GAG-polyprotein viral zinc-finger SHE3 PF17078.3 001291198.1_33429001_1 - 0.11 12.1 4.7 0.22 11.1 4.7 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ZapB PF06005.10 001291198.1_33429001_1 - 0.11 12.8 7.5 0.25 11.7 7.5 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Spc7 PF08317.9 001291198.1_33429001_1 - 0.19 10.4 3.3 0.34 9.6 3.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291198.1_33429001_1 - 0.23 12.0 2.9 0.54 10.8 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CENP-H PF05837.10 001291198.1_33429001_1 - 0.38 11.0 3.7 0.82 10.0 3.7 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SR-25 PF10500.7 001291198.1_33429001_1 - 0.62 9.5 12.9 0.0067 15.9 4.8 1.8 2 0 0 2 2 1 0 Nuclear RNA-splicing-associated protein FlxA PF14282.4 001291198.1_33429001_1 - 0.81 9.6 5.9 1.7 8.5 5.9 1.5 1 0 0 1 1 1 0 FlxA-like protein IncA PF04156.12 001291198.1_33429001_1 - 0.87 9.2 6.8 1.6 8.4 6.8 1.4 1 0 0 1 1 1 0 IncA protein zf-CCHC PF00098.21 001291198.1_33429001_1 - 0.88 9.6 6.2 0.36 10.9 2.2 2.5 2 0 0 2 2 2 0 Zinc knuckle GIT_CC PF16559.3 001291198.1_33429001_1 - 2.1 8.3 6.7 5.4 7.0 6.7 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291198.1_33429001_1 - 4.9 7.7 5.9 12 6.5 5.9 1.6 1 0 0 1 1 1 0 SlyX DivIC PF04977.13 001291198.1_33429001_1 - 5.4 6.7 7.3 12 5.6 7.3 1.6 1 0 0 1 1 1 0 Septum formation initiator RCDG1 PF15725.3 001291198.1_33429001_1 - 6.9 7.0 11.6 20 5.6 11.6 1.8 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein TSC22 PF01166.16 001291198.1_33429001_1 - 8.2 6.7 7.1 40 4.5 7.1 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family Asp_protease_2 PF13650.4 001291198.1_33429001_3 - 0.00048 20.6 0.0 0.00078 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291198.1_33429001_3 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291198.1_33429001_3 - 0.05 14.0 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001291231.1_26729001_2 - 0.00032 21.2 0.0 0.00053 20.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291231.1_26729001_2 - 0.0083 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291231.1_26729001_2 - 0.047 14.1 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291231.1_26729001_3 - 4.6e-15 55.3 0.0 8.6e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291231.1_26729001_3 - 6.3e-15 55.1 1.9 1.7e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.4 001291231.1_26729001_3 - 0.0018 17.8 0.2 0.0043 16.6 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001291231.1_26729001_3 - 0.0036 17.0 3.8 0.006 16.3 3.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc29 PF17082.3 001291231.1_26729001_3 - 0.038 13.7 0.2 0.063 13.0 0.2 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Rootletin PF15035.4 001291231.1_26729001_3 - 0.11 12.4 6.6 0.2 11.5 6.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.10 001291231.1_26729001_3 - 0.15 12.4 9.0 0.33 11.3 9.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF1664 PF07889.10 001291231.1_26729001_3 - 0.28 11.1 0.8 0.56 10.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.12 001291231.1_26729001_3 - 0.3 10.7 1.6 0.61 9.7 1.6 1.4 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.11 001291231.1_26729001_3 - 0.44 11.1 2.8 1.1 9.8 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.19 001291231.1_26729001_3 - 0.53 10.3 5.6 1.4 8.9 4.4 2.0 1 1 0 1 1 1 0 bZIP transcription factor CCDC106 PF15794.3 001291231.1_26729001_3 - 0.62 9.6 3.0 1.1 8.8 3.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001291231.1_26729001_3 - 0.8 10.0 4.3 1.9 8.8 4.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.13 001291231.1_26729001_3 - 0.92 9.2 4.5 2.4 7.9 4.5 1.6 1 0 0 1 1 1 0 Septum formation initiator SHE3 PF17078.3 001291231.1_26729001_3 - 1.1 8.8 5.6 0.65 9.5 3.9 1.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 SlyX PF04102.10 001291231.1_26729001_3 - 1.8 9.1 4.5 4.6 7.8 4.5 1.6 1 0 0 1 1 1 0 SlyX GIT_CC PF16559.3 001291231.1_26729001_3 - 4.1 7.4 7.3 14 5.7 7.3 1.9 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Asp_protease_2 PF13650.4 001291243.1_31929001_1 - 0.0023 18.4 0.0 0.0035 17.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291243.1_31929001_1 - 0.0024 17.7 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291243.1_31929001_1 - 0.038 14.4 0.0 0.055 13.9 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291243.1_31929001_2 - 7.1e-18 64.4 0.0 1.3e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291243.1_31929001_2 - 3e-17 62.6 0.3 5.6e-17 61.7 0.3 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_5 PF14787.4 001291243.1_31929001_2 - 0.00054 19.5 0.3 0.0013 18.3 0.3 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.21 001291243.1_31929001_2 - 0.049 13.6 1.8 0.14 12.2 1.8 1.9 1 0 0 1 1 1 0 Zinc knuckle DUF5129 PF17173.2 001291243.1_31929001_2 - 0.23 10.4 1.3 0.36 9.8 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Mito_fiss_reg PF05308.9 001291243.1_31929001_2 - 2.2 8.2 5.5 4.7 7.1 5.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Toxin_11 PF07473.9 001291250.1_11329001_1 - 0.58 10.2 4.2 6.7 6.8 4.2 2.9 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species Asp_protease_2 PF13650.4 001291250.1_11329001_2 - 0.0029 18.1 0.0 0.0046 17.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291250.1_11329001_2 - 0.013 15.4 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291250.1_11329001_2 - 0.18 12.2 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291250.1_11329001_3 - 9.7e-14 51.3 1.3 2.4e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291250.1_11329001_3 - 2.2e-13 49.9 0.0 3.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291250.1_11329001_3 - 0.00032 20.5 1.4 0.00054 19.7 1.4 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291250.1_11329001_3 - 0.0032 17.0 2.9 0.0033 17.0 0.2 2.2 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291250.1_11329001_3 - 0.004 16.9 0.1 0.0065 16.2 0.1 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 SlyX PF04102.10 001291250.1_11329001_3 - 0.032 14.7 3.9 0.091 13.3 3.9 1.7 1 0 0 1 1 1 0 SlyX bZIP_1 PF00170.19 001291250.1_11329001_3 - 0.075 13.0 1.7 0.22 11.5 1.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor Rootletin PF15035.4 001291250.1_11329001_3 - 0.1 12.5 3.9 0.2 11.6 3.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.17 001291250.1_11329001_3 - 0.2 9.4 1.8 0.26 9.0 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GIT_CC PF16559.3 001291250.1_11329001_3 - 0.24 11.3 5.2 0.44 10.5 5.2 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.10 001291250.1_11329001_3 - 0.61 10.4 6.8 1.5 9.2 6.8 1.5 1 0 0 1 1 1 0 Cell division protein ZapB zf-CCHC PF00098.21 001291250.1_11329001_3 - 0.73 9.9 7.2 0.25 11.4 2.2 2.9 2 0 0 2 2 2 0 Zinc knuckle CENP-H PF05837.10 001291250.1_11329001_3 - 1.1 9.6 4.4 2.2 8.6 4.4 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.13 001291250.1_11329001_3 - 1.1 8.9 3.5 3 7.5 3.5 1.7 1 0 0 1 1 1 0 Septum formation initiator zf-CCHC_2 PF13696.4 001291250.1_11329001_3 - 2.1 8.1 10.6 0.72 9.6 0.7 3.1 2 0 0 2 2 2 0 Zinc knuckle IncA PF04156.12 001291250.1_11329001_3 - 2.2 7.9 4.6 4.9 6.8 4.6 1.5 1 0 0 1 1 1 0 IncA protein Retrotrans_gag PF03732.15 001291312.1_40029001_1 - 3.3e-15 56.0 2.6 4.5e-15 55.6 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291312.1_40029001_1 - 7.6e-15 54.6 0.0 1.3e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001291312.1_40029001_1 - 0.0019 17.7 0.2 0.0048 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001291312.1_40029001_1 - 0.015 15.1 4.9 0.024 14.4 4.9 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001291312.1_40029001_1 - 0.056 13.4 6.4 0.1 12.6 6.4 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.10 001291312.1_40029001_1 - 0.24 11.3 4.6 0.42 10.5 4.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SHE3 PF17078.3 001291312.1_40029001_1 - 0.32 10.6 5.3 0.53 9.8 5.3 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.19 001291312.1_40029001_1 - 0.33 11.0 5.2 0.88 9.6 5.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.11 001291312.1_40029001_1 - 0.64 10.5 3.7 1.4 9.4 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001291312.1_40029001_1 - 0.75 8.5 4.2 1.3 7.7 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mito_fiss_reg PF05308.9 001291312.1_40029001_1 - 0.78 9.6 5.4 1.5 8.7 5.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator ZapB PF06005.10 001291312.1_40029001_1 - 1.5 9.2 9.4 3.2 8.1 9.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.13 001291312.1_40029001_1 - 6 6.6 4.9 14 5.4 4.9 1.5 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.16 001291312.1_40029001_1 - 9.7 6.5 7.0 69 3.7 7.0 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family Asp_protease_2 PF13650.4 001291312.1_40029001_3 - 0.00064 20.2 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291312.1_40029001_3 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291312.1_40029001_3 - 0.059 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001291334.1_08629001_1 - 0.00036 21.0 0.0 0.00058 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291334.1_08629001_1 - 0.017 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291334.1_08629001_1 - 0.058 13.8 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291334.1_08629001_2 - 1.2e-15 57.4 2.0 1.1e-14 54.3 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291334.1_08629001_2 - 6.7e-15 54.8 0.1 1.7e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291334.1_08629001_2 - 0.00031 20.5 2.2 0.00055 19.7 2.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001291334.1_08629001_2 - 0.0015 18.5 2.7 0.0027 17.7 2.7 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion zf-CCHC_5 PF14787.4 001291334.1_08629001_2 - 0.0019 17.8 0.2 0.0049 16.4 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CASP_C PF08172.10 001291334.1_08629001_2 - 0.0064 15.7 0.0 0.0097 15.1 0.0 1.2 1 0 0 1 1 1 1 CASP C terminal CENP-H PF05837.10 001291334.1_08629001_2 - 0.08 13.2 3.3 0.18 12.1 3.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-CCHC PF00098.21 001291334.1_08629001_2 - 0.1 12.6 2.2 0.35 10.9 2.2 2.1 1 0 0 1 1 1 0 Zinc knuckle SHE3 PF17078.3 001291334.1_08629001_2 - 0.11 12.1 4.5 0.23 11.0 4.5 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 IncA PF04156.12 001291334.1_08629001_2 - 0.14 11.8 4.1 0.28 10.8 4.1 1.4 1 0 0 1 1 1 0 IncA protein ZapB PF06005.10 001291334.1_08629001_2 - 0.21 12.0 8.6 0.58 10.5 8.6 1.7 1 0 0 1 1 1 0 Cell division protein ZapB TolA_bind_tri PF16331.3 001291334.1_08629001_2 - 0.24 11.4 3.9 0.53 10.3 3.9 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.6 001291334.1_08629001_2 - 0.28 11.1 5.5 0.7 9.8 5.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.9 001291334.1_08629001_2 - 0.36 9.5 4.8 0.6 8.8 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.6 001291334.1_08629001_2 - 0.36 9.9 2.5 0.61 9.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF972 PF06156.11 001291334.1_08629001_2 - 0.38 11.3 3.5 0.9 10.1 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.13 001291334.1_08629001_2 - 0.95 9.1 5.3 3 7.5 5.3 1.9 1 0 0 1 1 1 0 Septum formation initiator RCDG1 PF15725.3 001291334.1_08629001_2 - 0.99 9.7 10.5 2.5 8.5 10.5 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DUF3446 PF11928.6 001291334.1_08629001_2 - 1.4 9.2 12.1 4.4 7.6 12.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) GIT_CC PF16559.3 001291334.1_08629001_2 - 1.6 8.7 6.8 3.7 7.5 6.8 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291334.1_08629001_2 - 1.9 9.0 5.0 4.8 7.7 5.0 1.6 1 0 0 1 1 1 0 SlyX bZIP_1 PF00170.19 001291334.1_08629001_2 - 2 8.4 8.4 6.9 6.7 8.5 1.9 1 1 0 1 1 1 0 bZIP transcription factor Mito_fiss_reg PF05308.9 001291334.1_08629001_3 - 1.7 8.6 6.7 3.3 7.6 6.7 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Asp_protease_2 PF13650.4 001291330.1_52129001_1 - 0.00032 21.2 0.0 0.00058 20.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291330.1_52129001_1 - 0.0082 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291330.1_52129001_1 - 0.037 14.5 0.0 0.061 13.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291330.1_52129001_2 - 1.3e-15 57.3 1.8 1.4e-14 54.0 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291330.1_52129001_2 - 5.4e-15 55.1 0.0 9.6e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291330.1_52129001_2 - 0.0033 17.2 5.3 0.0055 16.4 5.3 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291330.1_52129001_2 - 0.0044 16.6 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291330.1_52129001_2 - 0.019 14.9 8.8 0.035 14.0 8.8 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.10 001291330.1_52129001_2 - 0.15 12.4 4.4 0.3 11.4 4.4 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CCDC106 PF15794.3 001291330.1_52129001_2 - 0.22 11.1 2.1 0.4 10.2 2.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 bZIP_1 PF00170.19 001291330.1_52129001_2 - 0.23 11.4 5.7 0.7 9.9 5.7 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.11 001291330.1_52129001_2 - 0.24 11.9 3.6 0.62 10.6 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1664 PF07889.10 001291330.1_52129001_2 - 0.25 11.2 1.0 0.53 10.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.12 001291330.1_52129001_2 - 0.3 10.7 5.2 0.64 9.6 5.2 1.5 1 0 0 1 1 1 0 IncA protein SlyX PF04102.10 001291330.1_52129001_2 - 0.33 11.5 2.9 0.9 10.1 2.9 1.7 1 0 0 1 1 1 0 SlyX ERM PF00769.17 001291330.1_52129001_2 - 0.38 10.4 6.1 0.63 9.7 6.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ZapB PF06005.10 001291330.1_52129001_2 - 0.39 11.1 10.0 0.9 9.9 10.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Spc7 PF08317.9 001291330.1_52129001_2 - 0.41 9.4 5.3 0.76 8.5 5.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.3 001291330.1_52129001_2 - 0.53 10.3 5.7 1 9.4 5.7 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.6 001291330.1_52129001_2 - 0.81 9.6 7.3 1.6 8.7 7.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SHE3 PF17078.3 001291330.1_52129001_2 - 1.9 8.0 7.1 3.4 7.2 7.1 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF3450 PF11932.6 001291330.1_52129001_2 - 2.3 7.3 4.3 3.9 6.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GIT_CC PF16559.3 001291330.1_52129001_2 - 3.2 7.7 8.2 8.7 6.3 8.2 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.13 001291330.1_52129001_2 - 3.3 7.4 7.8 9.9 5.9 7.8 1.8 1 1 0 1 1 1 0 Septum formation initiator Asp_protease_2 PF13650.4 001291337.1_52729001_1 - 0.00035 21.1 0.0 0.00058 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291337.1_52729001_1 - 0.017 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291337.1_52729001_1 - 0.056 13.9 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291337.1_52729001_2 - 1.3e-15 57.3 2.0 1.1e-14 54.3 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291337.1_52729001_2 - 9.7e-15 54.3 0.0 1.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291337.1_52729001_2 - 0.00041 20.1 2.5 0.00069 19.4 2.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291337.1_52729001_2 - 0.0016 18.0 0.2 0.0049 16.4 0.2 1.9 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291337.1_52729001_2 - 0.0019 18.2 2.9 0.0033 17.4 2.9 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CASP_C PF08172.10 001291337.1_52729001_2 - 0.0079 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 CASP C terminal bZIP_1 PF00170.19 001291337.1_52729001_2 - 0.018 15.0 2.0 0.058 13.4 2.0 1.9 1 0 0 1 1 1 0 bZIP transcription factor CENP-H PF05837.10 001291337.1_52729001_2 - 0.088 13.1 3.3 0.18 12.1 3.3 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SR-25 PF10500.7 001291337.1_52729001_2 - 0.093 12.2 2.2 0.25 10.8 2.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.21 001291337.1_52729001_2 - 0.11 12.5 2.2 0.35 10.9 2.2 2.0 1 0 0 1 1 1 0 Zinc knuckle SHE3 PF17078.3 001291337.1_52729001_2 - 0.12 11.9 4.5 0.23 11.0 4.5 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 IncA PF04156.12 001291337.1_52729001_2 - 0.15 11.7 4.0 0.26 10.9 4.0 1.3 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.6 001291337.1_52729001_2 - 0.24 10.5 2.0 0.4 9.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.10 001291337.1_52729001_2 - 0.27 11.5 8.6 0.58 10.5 8.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB TolA_bind_tri PF16331.3 001291337.1_52729001_2 - 0.28 11.1 3.9 0.53 10.3 3.9 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Spc7 PF08317.9 001291337.1_52729001_2 - 0.36 9.5 4.8 0.6 8.8 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291337.1_52729001_2 - 0.37 11.3 3.5 0.9 10.1 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.6 001291337.1_52729001_2 - 0.38 10.6 5.5 0.7 9.8 5.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.13 001291337.1_52729001_2 - 1.2 8.8 5.3 3 7.5 5.3 1.7 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291337.1_52729001_2 - 1.6 8.7 6.8 3.7 7.5 6.8 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291337.1_52729001_2 - 2.1 8.9 5.0 4.8 7.7 5.0 1.5 1 0 0 1 1 1 0 SlyX RCDG1 PF15725.3 001291337.1_52729001_2 - 2.3 8.6 9.1 6 7.2 9.1 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Retrotrans_gag PF03732.15 001291341.1_28326001_1 - 3e-16 59.4 2.2 4.1e-15 55.7 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291341.1_28326001_1 - 2.4e-15 56.2 0.0 4.5e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291341.1_28326001_1 - 2.6e-05 24.3 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291341.1_28326001_1 - 0.0002 21.2 4.3 0.00036 20.3 4.3 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291341.1_28326001_1 - 0.00078 19.0 0.2 0.002 17.7 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CASP_C PF08172.10 001291341.1_28326001_1 - 0.00094 18.5 0.1 0.0015 17.8 0.1 1.2 1 0 0 1 1 1 1 CASP C terminal SR-25 PF10500.7 001291341.1_28326001_1 - 0.006 16.1 6.4 0.006 16.1 6.4 2.3 3 0 0 3 3 2 1 Nuclear RNA-splicing-associated protein CENP-H PF05837.10 001291341.1_28326001_1 - 0.036 14.3 4.3 0.11 12.8 4.3 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-CCHC PF00098.21 001291341.1_28326001_1 - 0.049 13.6 2.2 0.14 12.1 2.2 1.9 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_C PF04871.11 001291341.1_28326001_1 - 0.053 13.7 3.8 0.088 13.0 3.8 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF972 PF06156.11 001291341.1_28326001_1 - 0.059 13.9 2.7 0.19 12.2 2.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291341.1_28326001_1 - 0.06 13.7 8.3 0.18 12.1 8.3 1.7 1 0 0 1 1 1 0 Cell division protein ZapB eIF3g PF12353.6 001291341.1_28326001_1 - 0.083 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G SHE3 PF17078.3 001291341.1_28326001_1 - 0.088 12.4 6.0 0.039 13.5 3.4 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.9 001291341.1_28326001_1 - 0.089 11.5 4.4 0.18 10.5 4.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.10 001291341.1_28326001_1 - 0.11 12.4 0.6 0.25 11.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.17 001291341.1_28326001_1 - 0.12 10.1 0.4 0.16 9.7 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.6 001291341.1_28326001_1 - 0.13 12.1 5.5 0.27 11.1 5.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TolA_bind_tri PF16331.3 001291341.1_28326001_1 - 0.16 12.0 4.9 0.4 10.7 4.9 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation IncA PF04156.12 001291341.1_28326001_1 - 0.27 10.9 8.0 0.53 9.9 8.0 1.4 1 0 0 1 1 1 0 IncA protein Prominin PF05478.9 001291341.1_28326001_1 - 0.3 8.9 1.0 0.46 8.2 1.0 1.2 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.6 001291341.1_28326001_1 - 0.38 9.9 5.4 0.68 9.0 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.10 001291341.1_28326001_1 - 0.61 10.6 5.3 2.2 8.8 5.3 1.9 1 0 0 1 1 1 0 SlyX RasGAP_C PF03836.13 001291341.1_28326001_1 - 1.7 8.6 5.6 4.9 7.2 2.5 3.0 4 0 0 4 4 4 0 RasGAP C-terminus GIT_CC PF16559.3 001291341.1_28326001_1 - 1.8 8.5 8.6 5.9 6.9 8.6 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.4 001291341.1_28326001_1 - 2.1 8.3 9.8 7.7 6.4 9.8 1.9 1 1 0 1 1 1 0 FlxA-like protein RCDG1 PF15725.3 001291341.1_28326001_1 - 2.7 8.3 11.6 7.9 6.9 11.6 1.8 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein TSC22 PF01166.16 001291341.1_28326001_1 - 5.1 7.4 7.4 32 4.8 7.4 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family HALZ PF02183.16 001291341.1_28326001_1 - 5.3 7.2 5.7 12 6.1 3.8 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper APG6 PF04111.10 001291341.1_28326001_1 - 6.1 6.0 7.0 1.8 7.7 4.0 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 XhlA PF10779.7 001291341.1_28326001_1 - 9.9 6.3 6.2 19 5.4 6.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Asp_protease_2 PF13650.4 001291341.1_28326001_3 - 0.00017 22.1 0.0 0.00028 21.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291341.1_28326001_3 - 0.0041 17.0 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291341.1_28326001_3 - 0.018 15.5 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001291350.1_12129001_2 - 0.00028 21.4 0.0 0.00045 20.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291350.1_12129001_2 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease PRIMA1 PF16101.3 001291350.1_12129001_2 - 0.014 15.3 0.8 0.014 15.3 0.8 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 gag-asp_proteas PF13975.4 001291350.1_12129001_2 - 0.029 14.8 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291350.1_12129001_3 - 2.2e-15 56.4 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291350.1_12129001_3 - 2.5e-14 53.2 3.2 7.7e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein KASH_CCD PF14662.4 001291350.1_12129001_3 - 0.00014 21.6 5.5 0.00024 20.9 5.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001291350.1_12129001_3 - 0.00029 20.8 0.1 0.00052 20.0 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion zf-CCHC_5 PF14787.4 001291350.1_12129001_3 - 0.0029 17.1 0.2 0.0084 15.7 0.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger IncA PF04156.12 001291350.1_12129001_3 - 0.013 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 IncA protein Uso1_p115_C PF04871.11 001291350.1_12129001_3 - 0.023 14.9 3.9 0.037 14.3 3.9 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.10 001291350.1_12129001_3 - 0.031 14.6 7.9 0.085 13.2 7.9 1.7 1 0 0 1 1 1 0 Cell division protein ZapB CCDC106 PF15794.3 001291350.1_12129001_3 - 0.05 13.2 1.0 0.1 12.2 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TolA_bind_tri PF16331.3 001291350.1_12129001_3 - 0.055 13.4 3.3 0.11 12.5 3.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3450 PF11932.6 001291350.1_12129001_3 - 0.14 11.3 5.9 0.22 10.6 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ERM PF00769.17 001291350.1_12129001_3 - 0.16 11.7 5.9 0.27 10.9 5.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.10 001291350.1_12129001_3 - 0.16 11.8 1.4 0.33 10.8 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.9 001291350.1_12129001_3 - 0.17 10.6 4.5 0.31 9.7 4.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291350.1_12129001_3 - 0.28 11.7 3.4 0.7 10.4 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) SlyX PF04102.10 001291350.1_12129001_3 - 0.38 11.3 4.6 0.14 12.6 1.5 1.9 2 0 0 2 2 1 0 SlyX TMF_DNA_bd PF12329.6 001291350.1_12129001_3 - 0.5 10.3 8.5 0.95 9.4 8.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.13 001291350.1_12129001_3 - 0.57 9.9 5.1 1.4 8.6 5.1 1.6 1 0 0 1 1 1 0 Septum formation initiator CENP-H PF05837.10 001291350.1_12129001_3 - 0.58 10.4 4.4 1.2 9.4 4.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_1 PF00170.19 001291350.1_12129001_3 - 1.2 9.2 8.0 3.1 7.8 8.0 1.7 1 0 0 1 1 1 0 bZIP transcription factor SHE3 PF17078.3 001291350.1_12129001_3 - 1.7 8.2 8.1 0.59 9.7 5.3 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 GIT_CC PF16559.3 001291350.1_12129001_3 - 2.4 8.1 7.6 6.9 6.7 7.6 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.16 001291350.1_12129001_3 - 7.6 6.7 6.8 7.4 6.7 2.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4939 PF16297.3 001291360.1_20626001_1 - 3.3e-14 52.6 0.0 6.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291360.1_20626001_1 - 1.3e-13 50.9 2.5 1.5e-13 50.7 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.4 001291360.1_20626001_1 - 0.00062 19.3 0.2 0.0015 18.1 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.21 001291360.1_20626001_1 - 0.046 13.7 2.2 0.13 12.2 2.2 1.9 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.6 001291360.1_20626001_1 - 0.14 12.4 0.1 0.14 12.4 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Asp-B-Hydro_N PF05279.9 001291360.1_20626001_1 - 0.59 10.0 11.2 0.95 9.3 11.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2052 PF09747.7 001291360.1_20626001_1 - 1.3 9.0 10.5 2.3 8.2 10.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC27 PF09507.8 001291360.1_20626001_1 - 3.7 6.7 15.7 6.1 6.0 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp_protease_2 PF13650.4 001291360.1_20626001_3 - 0.0053 17.3 0.0 0.0091 16.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291360.1_20626001_3 - 0.017 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291360.1_20626001_3 - 0.14 12.6 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001291362.1_44829001_1 - 0.0035 17.9 0.0 0.0063 17.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291362.1_44829001_1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291362.1_44829001_1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291362.1_44829001_2 - 2.1e-15 56.4 0.0 3.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291362.1_44829001_2 - 5.6e-15 55.3 0.0 5.6e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.4 001291362.1_44829001_2 - 0.0049 16.4 0.2 0.0049 16.4 0.2 1.9 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001291362.1_44829001_2 - 0.0091 15.7 2.8 0.015 15.0 2.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC PF00098.21 001291362.1_44829001_2 - 0.076 13.0 2.2 0.35 10.9 2.2 2.3 1 0 0 1 1 1 0 Zinc knuckle ZapB PF06005.10 001291362.1_44829001_2 - 0.1 12.9 7.4 0.21 11.9 7.4 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Rootletin PF15035.4 001291362.1_44829001_2 - 0.71 9.8 7.9 0.033 14.1 2.1 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.13 001291362.1_44829001_2 - 1.4 8.6 3.8 3.4 7.4 3.8 1.6 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.9 001291362.1_44829001_2 - 1.6 7.4 4.7 1.6 7.4 3.5 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Asp_protease_2 PF13650.4 001291364.1_41226001_1 - 0.0011 19.5 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291364.1_41226001_1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291364.1_41226001_1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291364.1_41226001_2 - 1.9e-16 60.0 0.0 3.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.3 001291364.1_41226001_2 - 9.3e-11 41.5 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001291364.1_41226001_2 - 0.00027 20.4 0.3 0.00069 19.1 0.3 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.21 001291364.1_41226001_2 - 0.027 14.4 1.8 0.074 13.0 1.8 1.8 1 0 0 1 1 1 0 Zinc knuckle COX17 PF05051.11 001291364.1_41226001_3 - 4.2 7.7 7.4 1.5 9.1 0.7 2.6 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Asp_protease_2 PF13650.4 001291372.1_42229001_2 - 0.00036 21.0 0.0 0.00059 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291372.1_42229001_2 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291372.1_42229001_2 - 0.058 13.8 0.0 0.097 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291372.1_42229001_3 - 7.7e-15 54.8 3.4 1.2e-14 54.3 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291372.1_42229001_3 - 1.7e-14 53.5 0.0 3.1e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291372.1_42229001_3 - 0.0016 18.2 5.8 0.0026 17.5 5.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291372.1_42229001_3 - 0.0019 17.7 0.2 0.0049 16.4 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291372.1_42229001_3 - 0.054 13.4 7.9 0.098 12.6 7.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CCDC106 PF15794.3 001291372.1_42229001_3 - 0.085 12.4 1.4 0.2 11.2 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 IncA PF04156.12 001291372.1_42229001_3 - 0.26 10.9 4.3 0.49 10.0 4.3 1.3 1 0 0 1 1 1 0 IncA protein TolA_bind_tri PF16331.3 001291372.1_42229001_3 - 0.37 10.8 4.3 0.7 9.9 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation SHE3 PF17078.3 001291372.1_42229001_3 - 0.43 10.1 6.9 0.82 9.2 6.9 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CENP-H PF05837.10 001291372.1_42229001_3 - 0.43 10.9 3.7 0.84 9.9 3.7 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.9 001291372.1_42229001_3 - 0.56 8.9 6.0 0.95 8.1 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.19 001291372.1_42229001_3 - 0.67 10.0 8.2 2.3 8.3 8.2 1.9 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.11 001291372.1_42229001_3 - 0.75 10.3 4.7 1.7 9.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291372.1_42229001_3 - 0.89 9.9 10.4 2 8.8 10.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.13 001291372.1_42229001_3 - 1.6 8.4 5.9 4.2 7.1 5.9 1.6 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291372.1_42229001_3 - 1.8 8.5 7.1 4.7 7.2 7.1 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291372.1_42229001_3 - 2.4 8.7 5.8 5.7 7.5 5.8 1.6 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291372.1_42229001_3 - 3 6.9 5.3 5 6.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Asp_protease_2 PF13650.4 001291374.1_05129001_2 - 0.00029 21.3 0.0 0.00058 20.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291374.1_05129001_2 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291374.1_05129001_2 - 0.05 14.0 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291374.1_05129001_3 - 6.5e-15 55.1 3.4 1.1e-14 54.3 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291374.1_05129001_3 - 1.7e-14 53.5 0.0 3.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291374.1_05129001_3 - 0.0015 18.3 5.8 0.0026 17.5 5.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291374.1_05129001_3 - 0.002 17.7 0.2 0.0049 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291374.1_05129001_3 - 0.056 13.4 7.9 0.097 12.6 7.9 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion zf-CCHC PF00098.21 001291374.1_05129001_3 - 0.078 13.0 2.2 0.35 10.9 2.2 2.3 1 0 0 1 1 1 0 Zinc knuckle CCDC106 PF15794.3 001291374.1_05129001_3 - 0.086 12.4 1.4 0.2 11.2 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 IncA PF04156.12 001291374.1_05129001_3 - 0.29 10.7 4.5 0.55 9.9 4.5 1.3 1 0 0 1 1 1 0 IncA protein TolA_bind_tri PF16331.3 001291374.1_05129001_3 - 0.38 10.7 4.3 0.7 9.9 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation CENP-H PF05837.10 001291374.1_05129001_3 - 0.4 11.0 3.7 0.84 9.9 3.7 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SHE3 PF17078.3 001291374.1_05129001_3 - 0.42 10.2 6.9 0.82 9.2 6.9 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.9 001291374.1_05129001_3 - 0.55 8.9 6.0 0.95 8.1 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291374.1_05129001_3 - 0.76 10.3 4.7 1.7 9.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291374.1_05129001_3 - 0.76 10.1 10.4 2 8.8 10.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.19 001291374.1_05129001_3 - 0.78 9.8 8.2 2.2 8.3 8.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.13 001291374.1_05129001_3 - 1.5 8.5 5.9 4.2 7.1 5.9 1.7 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291374.1_05129001_3 - 2 8.4 7.1 4.7 7.2 7.1 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291374.1_05129001_3 - 2.4 8.7 5.8 5.7 7.5 5.8 1.6 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291374.1_05129001_3 - 3.1 6.9 5.3 5 6.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.6 001291374.1_05129001_3 - 3.3 7.6 8.2 6.4 6.7 8.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Asp_protease_2 PF13650.4 001291377.1_28829001_1 - 0.00033 21.2 0.0 0.00058 20.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291377.1_28829001_1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291377.1_28829001_1 - 0.053 14.0 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291377.1_28829001_2 - 6.2e-15 55.1 3.3 6.6e-15 55.1 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291377.1_28829001_2 - 1.8e-14 53.5 0.0 3.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291377.1_28829001_2 - 0.00084 19.1 4.1 0.0016 18.2 4.1 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291377.1_28829001_2 - 0.0021 17.6 0.2 0.0049 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291377.1_28829001_2 - 0.051 13.5 7.5 0.089 12.7 7.5 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion zf-CCHC PF00098.21 001291377.1_28829001_2 - 0.1 12.6 2.2 0.35 10.9 2.2 2.0 1 0 0 1 1 1 0 Zinc knuckle bZIP_1 PF00170.19 001291377.1_28829001_2 - 0.18 11.8 7.2 0.56 10.2 7.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor CENP-H PF05837.10 001291377.1_28829001_2 - 0.28 11.5 3.0 0.71 10.2 3.0 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SHE3 PF17078.3 001291377.1_28829001_2 - 0.31 10.6 6.6 0.64 9.6 6.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ZapB PF06005.10 001291377.1_28829001_2 - 0.5 10.7 9.7 1.2 9.5 9.7 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291377.1_28829001_2 - 0.58 10.7 4.2 1.3 9.5 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CCDC106 PF15794.3 001291377.1_28829001_2 - 0.62 9.6 3.7 0.27 10.8 1.4 1.5 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 106 IncA PF04156.12 001291377.1_28829001_2 - 0.8 9.3 5.9 1.5 8.5 5.9 1.3 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.9 001291377.1_28829001_2 - 1.1 7.9 6.5 2 7.1 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.10 001291377.1_28829001_2 - 2 9.0 5.8 6.1 7.4 5.8 1.8 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291377.1_28829001_2 - 2.4 7.2 5.2 4.1 6.5 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.13 001291377.1_28829001_2 - 3.5 7.3 7.4 8.6 6.1 7.4 1.6 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291377.1_28829001_2 - 6.7 6.7 7.6 16 5.5 7.6 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291377.1_28829001_2 - 8.2 6.7 6.5 36 4.6 6.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family ODC_AZ PF02100.15 001291385.1_41223001_3 - 2e-20 72.8 0.0 3.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme RskA PF10099.7 001291385.1_41223001_3 - 0.0049 17.1 2.5 0.0078 16.4 2.5 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA ODC_AZ PF02100.15 001291397.1_28823001_3 - 4.7e-20 71.6 0.0 7.9e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001291405.1_41224001_2 - 1e-19 70.4 0.0 1.7e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001291407.1_42224001_3 - 6.5e-20 71.1 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001291409.1_28824001_2 - 6.4e-20 71.1 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001291423.1_28822001_1 - 4.2e-15 55.6 0.0 6.1e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001292065.1_21222001_3 - 6.3e-18 64.7 0.0 9e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001292067.1_21222001_1 - 2.8e-20 72.3 0.0 4.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001292068.1_21222001_2 - 9.4e-15 54.5 0.0 1.3e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF4939 PF16297.3 001292093.1_37829001_1 - 5.5e-15 55.1 0.0 1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001292093.1_37829001_1 - 6.4e-14 51.9 3.0 1.4e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein KASH_CCD PF14662.4 001292093.1_37829001_1 - 0.0002 21.1 6.8 0.00033 20.4 6.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001292093.1_37829001_1 - 0.00038 20.5 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion zf-CCHC_5 PF14787.4 001292093.1_37829001_1 - 0.0055 16.2 0.2 0.014 15.0 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001292093.1_37829001_1 - 0.0098 15.6 0.6 0.016 14.9 0.6 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 IncA PF04156.12 001292093.1_37829001_1 - 0.016 14.9 0.7 0.029 14.0 0.7 1.3 1 0 0 1 1 1 0 IncA protein DUF737 PF05300.9 001292093.1_37829001_1 - 0.053 13.7 2.0 0.094 12.9 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ZapB PF06005.10 001292093.1_37829001_1 - 0.12 12.7 8.1 0.26 11.6 8.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.10 001292093.1_37829001_1 - 0.13 12.7 1.6 0.32 11.5 1.6 1.6 1 0 0 1 1 1 0 SlyX ERM PF00769.17 001292093.1_37829001_1 - 0.22 11.2 7.7 0.38 10.4 7.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.3 001292093.1_37829001_1 - 0.31 11.0 4.3 0.56 10.2 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF1664 PF07889.10 001292093.1_37829001_1 - 0.44 10.4 2.0 0.83 9.5 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.11 001292093.1_37829001_1 - 0.45 11.0 3.5 1 9.9 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3450 PF11932.6 001292093.1_37829001_1 - 0.51 9.5 7.1 0.81 8.8 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uso1_p115_C PF04871.11 001292093.1_37829001_1 - 0.56 10.4 7.8 0.92 9.8 7.8 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-H PF05837.10 001292093.1_37829001_1 - 1.1 9.5 4.8 2.4 8.5 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.6 001292093.1_37829001_1 - 1.1 9.1 7.9 2.1 8.3 7.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.9 001292093.1_37829001_1 - 1.3 7.7 6.7 2.2 6.9 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SHE3 PF17078.3 001292093.1_37829001_1 - 1.7 8.2 8.0 0.58 9.7 5.4 1.4 2 0 0 2 2 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001292093.1_37829001_1 - 1.7 8.3 5.2 4.2 7.1 5.2 1.6 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001292093.1_37829001_1 - 1.9 8.5 7.5 5.1 7.1 7.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.3 001292093.1_37829001_1 - 3.7 7.5 7.4 9.4 6.2 7.4 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Asp_protease_2 PF13650.4 001292093.1_37829001_3 - 0.00047 20.7 0.0 0.00078 19.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001292093.1_37829001_3 - 0.012 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001292093.1_37829001_3 - 0.046 14.1 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001292095.1_11729001_2 - 0.00078 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001292095.1_11729001_2 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001292095.1_11729001_2 - 0.053 13.9 0.0 0.086 13.3 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001292095.1_11729001_3 - 5.1e-15 55.4 1.9 1.9e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001292095.1_11729001_3 - 5.3e-15 55.1 0.0 9.4e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001292095.1_11729001_3 - 0.00035 20.6 0.1 0.00066 19.7 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001292095.1_11729001_3 - 0.0021 17.8 4.6 0.0035 17.1 4.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001292095.1_11729001_3 - 0.0031 17.0 0.2 0.0069 15.9 0.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001292095.1_11729001_3 - 0.0082 15.9 0.4 0.014 15.2 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 SlyX PF04102.10 001292095.1_11729001_3 - 0.23 12.0 2.4 0.71 10.4 2.4 1.9 1 0 0 1 1 1 0 SlyX CENP-H PF05837.10 001292095.1_11729001_3 - 0.43 10.9 5.2 0.85 9.9 4.7 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.10 001292095.1_11729001_3 - 0.59 10.5 9.7 1.4 9.3 9.7 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001292095.1_11729001_3 - 0.8 10.2 3.9 2 9.0 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.13 001292095.1_11729001_3 - 3.8 7.2 7.1 8.7 6.1 7.1 1.5 1 0 0 1 1 1 0 Septum formation initiator ODC_AZ PF02100.15 001289795.2_39523001_1 - 2.1e-20 72.7 0.0 3.8e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289806.2_36523001_2 - 1.7e-19 69.8 0.0 2.9e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme TYA PF01021.17 001289806.2_36523001_3 - 9.4 6.5 9.1 4.3 7.6 4.7 2.0 2 0 0 2 2 2 0 TYA transposon protein ODC_AZ PF02100.15 001289891.2_33822001_2 - 1.8e-20 72.9 0.0 3e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001301413.1_35722001_3 - 1e-14 54.3 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001301420.1_37422001_3 - 1.6e-15 56.9 0.0 2.4e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001301421.1_51322001_3 - 5.1e-14 52.1 0.0 7.4e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001301630.1_40022001_3 - 5.1e-15 55.4 0.0 7.4e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001301632.1_52722001_1 - 4.2e-15 55.6 0.0 6.2e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001301633.1_12122001_3 - 1.3e-16 60.5 0.0 1.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001301637.1_05122001_3 - 1.8e-15 56.8 0.0 2.7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001301638.1_28822001_3 - 4.3e-15 55.6 0.0 6.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Asp_protease_2 PF13650.4 001302512.1_36226001_1 - 2.5e-05 24.7 0.1 7.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.9 001302512.1_36226001_1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001302512.1_36226001_1 - 0.0051 17.2 0.0 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001302512.1_36226001_2 - 2.7e-15 56.3 0.8 3.7e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001302512.1_36226001_2 - 2.9e-14 52.8 0.0 6.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) RP-C_C PF11800.6 001302512.1_36226001_2 - 0.44 10.4 8.8 0.85 9.5 8.8 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.15 001302512.1_36226001_2 - 4.4 5.8 5.0 5.5 5.5 5.0 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.8 001302512.1_36226001_2 - 8.1 4.9 7.1 11 4.4 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Asp_protease_2 PF13650.4 001292087.2_21229001_1 - 0.00038 20.9 0.0 0.00066 20.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001292087.2_21229001_1 - 0.0046 16.8 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001292087.2_21229001_1 - 0.018 15.5 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001292087.2_21229001_2 - 2.8e-15 56.3 0.1 2.8e-15 56.3 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001292087.2_21229001_2 - 2.3e-14 53.1 0.0 4.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001292087.2_21229001_2 - 0.0012 18.3 0.2 0.0031 17.1 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001292087.2_21229001_2 - 0.0014 18.4 8.4 0.0024 17.6 8.4 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001292087.2_21229001_2 - 0.0077 16.2 12.9 0.016 15.2 12.9 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.17 001292087.2_21229001_2 - 0.031 12.1 2.5 0.043 11.6 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC106 PF15794.3 001292087.2_21229001_2 - 0.051 13.2 5.3 0.089 12.4 5.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TFIIA PF03153.11 001292087.2_21229001_2 - 0.051 13.4 16.5 0.083 12.7 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCHC PF00098.21 001292087.2_21229001_2 - 0.09 12.8 2.2 0.22 11.5 2.2 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF1664 PF07889.10 001292087.2_21229001_2 - 0.22 11.4 3.8 0.22 11.4 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.10 001292087.2_21229001_2 - 0.51 10.6 12.8 1.1 9.6 10.8 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001292087.2_21229001_2 - 0.96 10.0 10.3 2.9 8.5 10.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001292087.2_21229001_2 - 1.1 9.6 17.2 3.6 8.0 17.2 1.9 1 0 0 1 1 1 0 Cell division protein ZapB DUF4106 PF13388.4 001292087.2_21229001_2 - 1.4 7.9 11.0 2.5 7.1 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Spc7 PF08317.9 001292087.2_21229001_2 - 2.9 6.6 11.8 2.9 6.5 10.7 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein TBPIP PF07106.11 001292087.2_21229001_2 - 3.3 7.3 9.7 6.5 6.4 9.7 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.12 001292087.2_21229001_2 - 4 7.1 10.8 9.9 5.8 10.8 1.6 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.6 001292087.2_21229001_2 - 6.1 6.8 13.3 12 5.9 13.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.10 001292087.2_21229001_2 - 6.6 5.9 10.2 14 4.8 10.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 GIT_CC PF16559.3 001292087.2_21229001_2 - 7.4 6.6 10.3 37 4.3 10.3 2.0 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ODC_AZ PF02100.15 001289721.1_39623001_3 - 8.3e-20 70.8 0.0 1.4e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001301415.1_39622001_3 - 5.2e-15 55.3 0.0 8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Asp_protease_2 PF13650.4 001302494.1_39629001_2 - 0.0008 19.9 0.0 0.0013 19.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001302494.1_39629001_2 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001302494.1_39629001_2 - 0.053 13.9 0.0 0.085 13.3 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001302494.1_39629001_3 - 5.3e-15 55.1 0.0 9.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001302494.1_39629001_3 - 1.3e-14 54.1 1.9 5e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001302494.1_39629001_3 - 0.001 19.0 1.1 0.0019 18.2 1.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001302494.1_39629001_3 - 0.002 17.9 4.7 0.0033 17.2 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001302494.1_39629001_3 - 0.0025 17.3 0.9 0.0064 16.0 0.2 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001302494.1_39629001_3 - 0.0069 16.1 0.4 0.011 15.4 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 CENP-H PF05837.10 001302494.1_39629001_3 - 0.23 11.7 4.8 0.47 10.8 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.10 001302494.1_39629001_3 - 0.32 11.3 9.2 0.68 10.3 9.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001302494.1_39629001_3 - 0.33 11.5 3.8 0.79 10.3 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF5082 PF16888.3 001302494.1_39629001_3 - 0.41 10.9 3.9 0.68 10.2 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CCDC106 PF15794.3 001302494.1_39629001_3 - 0.65 9.5 4.2 0.55 9.8 2.2 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SHE3 PF17078.3 001302494.1_39629001_3 - 0.79 9.3 7.3 1.6 8.3 7.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001302494.1_39629001_3 - 1.1 8.9 5.9 2.3 7.9 5.9 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001302494.1_39629001_3 - 1.5 8.8 8.4 3.3 7.8 8.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 001302494.1_39629001_3 - 1.7 8.3 5.3 3.3 7.3 5.3 1.4 1 0 0 1 1 1 0 IncA protein GIT_CC PF16559.3 001302494.1_39629001_3 - 2.1 8.3 7.1 5.2 7.0 7.1 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001302494.1_39629001_3 - 7.4 6.8 7.5 39 4.5 7.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family TLV_coat PF00429.17 001308131.1_13125001_2 - 5.3e-29 101.2 0.0 5.3e-29 101.2 0.0 2.3 2 1 1 3 3 3 1 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 001308194.1_35725001_1 - 2.7e-08 32.8 0.8 2.7e-08 32.8 0.8 2.3 2 1 0 2 2 2 1 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 001305097.1_46227001_3 - 5.1e-66 223.4 6.0 3.2e-63 214.2 3.0 2.2 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 001304545.1_35726001_3 - 1.4e-65 222.0 2.1 1.4e-65 222.0 2.1 1.9 1 1 1 2 2 2 2 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 001304546.1_39626001_3 - 2.5e-68 231.0 7.0 5.2e-68 230.0 6.5 1.6 1 1 1 2 2 2 2 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 001306048.1_30127001_3 - 1e-65 222.4 5.9 1.6e-62 211.8 2.7 2.2 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 001306046.1_10828001_3 - 3.2e-66 224.0 6.3 4.6e-63 213.6 3.2 2.2 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 001305072.1_35727001_1 - 1.2e-65 222.1 8.3 1.6e-62 211.9 5.0 2.2 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) CwsA PF10814.6 001305072.1_35727001_1 - 0.16 12.0 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA TLV_coat PF00429.17 001306045.1_13127001_3 - 1.2e-66 225.4 6.6 3.2e-63 214.1 3.3 2.2 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) CwsA PF10814.6 001306045.1_13127001_3 - 0.1 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA FYVE PF01363.19 001305073.1_46727001_1 - 0.018 15.0 4.2 0.036 14.1 4.2 1.4 1 0 0 1 1 1 0 FYVE zinc finger TLV_coat PF00429.17 001305073.1_46727001_2 - 8.2e-64 216.1 8.0 1.8e-60 205.1 4.4 2.3 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) CwsA PF10814.6 001305073.1_46727001_2 - 0.058 13.4 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA TLV_coat PF00429.17 001305098.1_11727001_3 - 4.7e-67 226.8 6.6 1.4e-63 215.3 3.3 2.2 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) Trypsin PF00089.24 001330481.1_29223001_1 - 1.9e-62 210.8 0.0 2.6e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin Gla PF00594.18 001330481.1_29223001_1 - 1.4e-18 66.7 9.2 2.1e-18 66.1 7.3 2.1 1 1 1 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1986 PF09342.9 001330481.1_29223001_1 - 2.1e-11 44.1 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) FXa_inhibition PF14670.4 001330481.1_29223001_1 - 1.2e-08 34.9 11.4 1.2e-08 34.9 11.4 2.8 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF PF00008.25 001330481.1_29223001_1 - 8.7e-07 29.0 5.4 8.7e-07 29.0 5.4 2.9 2 0 0 2 2 2 1 EGF-like domain cEGF PF12662.5 001330481.1_29223001_1 - 5.2e-05 22.9 1.3 5.2e-05 22.9 1.3 3.4 3 1 0 3 3 3 1 Complement Clr-like EGF-like hEGF PF12661.5 001330481.1_29223001_1 - 0.0046 17.4 2.5 0.0046 17.4 2.5 3.4 2 1 0 2 2 2 1 Human growth factor-like EGF Trypsin_2 PF13365.4 001330481.1_29223001_1 - 0.051 14.3 0.0 0.28 11.9 0.0 2.2 2 1 0 2 2 2 0 Trypsin-like peptidase domain EGF_2 PF07974.11 001330481.1_29223001_1 - 0.076 13.3 21.0 0.066 13.5 5.4 3.0 1 1 1 2 2 2 0 EGF-like domain Sep15_SelM PF08806.9 144533.1_29623120_2 - 5.3e-22 77.7 0.0 1.1e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Sep15/SelM redox domain EF-hand_7 PF13499.4 001047118.1_29621001_1 - 0.00013 22.2 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.4 001047118.1_29621001_1 - 0.00071 19.2 0.1 0.0023 17.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.30 001047118.1_29621001_1 - 0.013 14.9 1.8 0.02 14.3 0.7 2.0 2 0 0 2 2 2 0 EF hand G-alpha PF00503.18 001244058.1_14223001_1 - 5.3e-123 410.5 2.1 6.1e-123 410.3 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001244058.1_14223001_1 - 2.2e-17 62.9 1.9 1e-12 47.7 0.1 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001244058.1_14223001_1 - 2e-05 23.9 2.5 0.0035 16.6 0.6 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.11 001244058.1_14223001_1 - 0.00016 21.8 0.5 0.58 10.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.9 001244058.1_14223001_1 - 0.084 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.4 001244058.1_14223001_1 - 0.092 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.4 001244058.1_14223001_1 - 0.097 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.16 001244058.1_14223001_1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.20 001244058.1_14223001_1 - 0.18 11.3 2.0 7.7 5.9 0.5 2.5 2 0 0 2 2 2 0 Ras family DAGK_acc PF00609.17 001081206.1_32929001_2 - 2.3e-47 161.2 0.0 6.4e-47 159.7 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.22 001081206.1_32929001_2 - 1.5e-28 98.8 0.0 2.9e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.20 001081206.1_32929001_2 - 1.5e-13 50.3 27.6 9e-11 41.4 16.1 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_2 PF12796.5 001081206.1_32929001_2 - 9.6e-12 45.2 0.1 1.9e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001081206.1_32929001_2 - 1.9e-08 34.3 0.1 0.0012 19.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001081206.1_32929001_2 - 3.4e-07 29.9 0.1 0.015 15.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.28 001081206.1_32929001_2 - 5.5e-07 29.6 0.6 0.031 14.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.4 001081206.1_32929001_2 - 5.7e-06 26.6 0.1 3e-05 24.3 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF3915 PF13054.4 033536.1_32926120_3 - 1.9 8.3 5.4 3.4 7.5 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) 7tm_1 PF00001.19 001009744.1_39525001_1 - 6.3e-52 176.3 22.1 1.1e-51 175.6 20.7 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001009744.1_39525001_1 - 2.1e-07 30.5 20.4 3.3e-07 29.8 20.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LIM PF00412.20 001025715.1_45723001_2 - 1.6e-10 40.9 10.1 2.5e-10 40.3 10.1 1.3 1 0 0 1 1 1 1 LIM domain LLC1 PF14945.4 001123088.1_49822001_2 - 1.6e-49 167.3 0.2 2.2e-49 166.9 0.2 1.2 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein POT1PC PF16686.3 001137635.2_49824001_1 - 1.7e-39 135.1 0.0 2.9e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.15 001137635.2_49824001_1 - 0.0077 15.9 0.0 0.033 13.9 0.0 2.1 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 PP-binding_2 PF14573.4 001137635.2_49824001_1 - 0.13 12.4 0.2 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Acyl-carrier LRR_8 PF13855.4 001244951.1_49826001_1 - 1.9e-16 59.4 11.0 1.9e-09 37.0 5.7 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.5 001244951.1_49826001_1 - 6.3e-13 48.5 8.9 2.9e-06 27.3 2.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001244951.1_49826001_1 - 0.0015 18.6 6.8 18 6.2 0.4 5.1 4 0 0 4 4 4 1 Leucine Rich Repeat Rrn6 PF10214.7 001244951.1_49826001_1 - 0.023 13.0 4.0 0.034 12.4 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4366 PF14283.4 001244951.1_49826001_1 - 0.063 12.6 1.8 0.062 12.6 0.6 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) PBP1_TM PF14812.4 001244951.1_49826001_1 - 9.3 6.6 14.7 0.34 11.2 7.8 2.0 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APG6 PF04111.10 001244951.1_49826001_1 - 9.7 5.3 20.2 14 4.9 20.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 G-alpha PF00503.18 001123115.1_49823001_1 - 2.5e-125 418.2 1.6 2.9e-125 418.0 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001123115.1_49823001_1 - 4.2e-18 65.3 0.1 3.6e-13 49.2 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001123115.1_49823001_1 - 2.1e-06 27.1 1.3 0.0067 15.7 0.8 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.11 001123115.1_49823001_1 - 7.4e-05 22.8 0.1 0.59 10.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.4 001123115.1_49823001_1 - 0.022 15.0 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.20 001123115.1_49823001_1 - 0.042 13.3 1.4 3.2 7.2 0.7 2.4 2 0 0 2 2 2 0 Ras family TniB PF05621.9 001123115.1_49823001_1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.4 001123115.1_49823001_1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Radial_spoke_3 PF06098.9 001168984.1_40423001_1 - 1.4e-129 431.3 8.1 1.4e-129 431.3 8.1 1.7 2 0 0 2 2 2 1 Radial spoke protein 3 ATP_synt_H PF05493.11 110612.1_26226120_1 - 1.4e-22 79.7 4.9 2.8e-22 78.8 4.9 1.5 1 0 0 1 1 1 1 ATP synthase subunit H Parathyroid PF01279.15 001082653.1_37922001_1 - 2e-33 115.1 0.7 4.2e-33 114.1 0.7 1.5 1 0 0 1 1 1 1 Parathyroid hormone family MTS PF05175.12 110977.1_32922120_1 - 3.8e-14 52.4 0.0 5.5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.11 110977.1_32922120_1 - 4.3e-12 45.9 0.2 5.7e-12 45.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.4 110977.1_32922120_1 - 5e-11 42.5 0.2 7.6e-11 41.9 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 110977.1_32922120_1 - 6.2e-09 36.3 0.0 9.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.13 110977.1_32922120_1 - 6.8e-09 35.5 0.0 9.6e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.8 110977.1_32922120_1 - 6.2e-06 26.0 0.2 8.4e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.16 110977.1_32922120_1 - 7.1e-06 25.7 0.3 5.3e-05 22.8 0.3 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.10 110977.1_32922120_1 - 0.00095 19.7 0.0 0.0016 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DNA_methylase PF00145.15 110977.1_32922120_1 - 0.0014 17.9 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_16 PF10294.7 110977.1_32922120_1 - 0.0015 18.1 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DUF43 PF01861.14 110977.1_32922120_1 - 0.0028 16.8 0.0 0.0038 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF43 Met_10 PF02475.14 110977.1_32922120_1 - 0.0053 16.4 0.1 0.0076 15.9 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.15 110977.1_32922120_1 - 0.0056 16.0 0.1 0.0079 15.5 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.16 110977.1_32922120_1 - 0.03 13.5 0.1 0.041 13.1 0.1 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.5 110977.1_32922120_1 - 0.036 13.9 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.17 110977.1_32922120_1 - 0.081 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_Mtase PF02384.14 110977.1_32922120_1 - 0.092 11.9 0.2 0.16 11.1 0.2 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase FmrO PF07091.9 110977.1_32922120_1 - 0.12 11.8 0.2 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) EF-hand_1 PF00036.30 001310223.1_25625001_1 - 2.7e-40 132.8 9.6 3.1e-09 35.6 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001310223.1_25625001_1 - 1.1e-34 118.6 2.7 6.4e-18 64.9 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001310223.1_25625001_1 - 4.4e-32 109.5 9.1 4.7e-14 51.8 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001310223.1_25625001_1 - 5e-28 94.5 5.7 8.1e-09 34.6 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001310223.1_25625001_1 - 9.1e-25 84.9 6.9 6.2e-06 25.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001310223.1_25625001_1 - 9.2e-14 51.4 0.2 2.7e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001310223.1_25625001_1 - 2.7e-08 33.6 0.2 0.00064 19.5 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001310223.1_25625001_1 - 3.7e-06 27.1 0.0 0.049 13.8 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001310223.1_25625001_1 - 0.00021 22.0 0.0 0.011 16.4 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.8 001310223.1_25625001_1 - 0.00049 20.0 0.6 0.001 19.0 0.1 1.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.11 001310223.1_25625001_1 - 0.0014 18.5 0.0 0.3 11.0 0.0 2.7 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF1103 PF06513.9 001310223.1_25625001_1 - 0.017 14.6 1.5 0.024 14.1 1.5 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) DUF4497 PF14924.4 001310223.1_25625001_1 - 0.045 14.1 0.0 9.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) DUF3349 PF11829.6 001310223.1_25625001_1 - 0.11 13.1 0.3 11 6.8 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Caleosin PF05042.11 001310223.1_25625001_1 - 0.15 11.8 0.1 3.8 7.3 0.0 2.6 1 1 2 3 3 3 0 Caleosin related protein RNA_pol_Rpb4 PF03874.14 001310223.1_25625001_1 - 0.2 11.8 0.5 11 6.2 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF755 PF05501.9 025385.3_32923001_3 - 6.9 6.8 21.7 12 6.1 21.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Kelch_1 PF01344.23 001161649.1_49826001_3 - 1.1e-84 277.7 14.7 1.4e-15 56.5 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.4 001161649.1_49826001_3 - 7.7e-45 149.7 4.9 1.2e-09 37.9 0.0 6.4 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.13 001161649.1_49826001_3 - 3.5e-34 115.3 4.0 3.1e-05 23.6 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.4 001161649.1_49826001_3 - 3.4e-33 113.1 19.8 1.9e-08 34.2 0.2 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.4 001161649.1_49826001_3 - 3.6e-30 103.5 3.2 9.5e-08 31.8 0.1 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB PF00651.29 001161649.1_49826001_3 - 8.7e-27 93.4 0.3 1.6e-26 92.5 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.4 001161649.1_49826001_3 - 4.5e-15 55.1 8.2 0.00034 20.4 0.1 5.8 6 0 0 6 6 6 5 Kelch motif BACK PF07707.13 001161649.1_49826001_3 - 1.1e-12 47.8 0.4 3.1e-12 46.4 0.2 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch PQQ_3 PF13570.4 001161649.1_49826001_3 - 1.7 9.1 10.6 8.7 6.8 0.1 4.2 5 0 0 5 5 5 0 PQQ-like domain Aminotran_1_2 PF00155.19 029391.1_49824120_1 - 1.1e-48 166.2 0.0 1.4e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.8 029391.1_49824120_1 - 4.7e-47 159.2 4.0 7.5e-47 158.5 4.0 1.3 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Aminotran_5 PF00266.17 029391.1_49824120_1 - 0.001 18.0 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.19 029391.1_49824120_2 - 3.3e-21 75.7 0.0 4.5e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II ODC_AZ PF02100.15 001301426.1_31322001_1 - 3e-15 56.1 0.0 4.4e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme TCTP PF00838.15 001279828.1_25622001_2 - 1e-80 269.7 0.3 1.2e-80 269.5 0.3 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein ESSS PF10183.7 001279848.2_25622001_2 - 3.4e-46 155.6 0.2 4.9e-46 155.1 0.2 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DNA_pol_B_palm PF14792.4 001310265.1_25623001_1 - 6.8e-40 135.7 0.1 1.4e-39 134.6 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.7 001310265.1_25623001_1 - 2.8e-21 75.0 0.1 7.5e-20 70.4 0.0 2.4 1 1 1 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.4 001310265.1_25623001_1 - 1e-19 70.5 0.3 6.1e-18 64.8 0.2 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.4 001310265.1_25623001_1 - 1e-17 63.9 0.0 2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_5 PF14520.4 001310265.1_25623001_1 - 2.3e-09 37.6 0.1 3.4e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain Cdd1 PF11731.6 001310265.1_25623001_1 - 0.00063 19.8 0.0 0.085 13.0 0.0 2.6 1 1 1 2 2 2 1 Pathogenicity locus HHH PF00633.21 001310265.1_25623001_1 - 0.00063 19.3 0.1 0.79 9.6 0.3 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.5 001310265.1_25623001_1 - 0.0035 17.4 0.3 11 6.3 0.0 3.9 4 1 0 4 4 4 1 Helix-hairpin-helix motif NTP_transf_2 PF01909.21 001310265.1_25623001_1 - 0.0059 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_2 PF12826.5 001310265.1_25623001_1 - 0.0086 16.0 0.0 1.1 9.3 0.0 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix motif WSN PF02206.16 001310265.1_25623001_1 - 0.015 15.0 0.1 12 5.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF3701 PF12482.6 001310265.1_25623001_1 - 0.05 13.5 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Phage integrase protein Pyr_redox_2 PF07992.12 001310225.1_25626001_3 - 4.5e-38 131.0 0.2 5.8e-38 130.7 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001310225.1_25626001_3 - 2.1e-14 53.7 0.3 6.5e-07 29.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.4 001310225.1_25626001_3 - 3.2e-08 33.0 0.1 1.3e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001310225.1_25626001_3 - 3.2e-05 23.1 0.6 0.11 11.4 0.2 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.22 001310225.1_25626001_3 - 6.9e-05 22.5 0.9 0.054 13.0 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.4 001310225.1_25626001_3 - 0.00017 20.7 0.0 0.00017 20.7 0.0 1.4 2 0 0 2 2 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.4 001310225.1_25626001_3 - 0.00063 19.8 0.2 0.022 14.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.15 001310225.1_25626001_3 - 0.0011 18.1 0.6 0.022 13.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.12 001310225.1_25626001_3 - 0.0037 15.9 0.9 1.5 7.3 0.1 2.6 3 0 0 3 3 3 2 HI0933-like protein Trp_halogenase PF04820.12 001310225.1_25626001_3 - 0.0073 15.1 1.5 3.7 6.2 0.2 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.10 001310225.1_25626001_3 - 0.01 14.8 0.6 0.37 9.6 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.19 001310225.1_25626001_3 - 0.014 14.5 2.2 0.051 12.7 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.4 001310225.1_25626001_3 - 0.026 14.4 0.8 16 5.3 0.1 3.3 4 0 0 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.16 001310225.1_25626001_3 - 0.034 14.3 0.1 10 6.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.22 001310225.1_25626001_3 - 0.037 13.0 1.3 0.44 9.4 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.5 001310225.1_25626001_3 - 0.12 11.6 2.2 0.48 9.6 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase RGS PF00615.17 001310247.1_25629001_3 - 3.9e-34 117.3 2.8 6.2e-34 116.7 2.8 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain AAA PF00004.27 001310283.1_25628001_3 - 3.7e-57 192.3 0.0 2.3e-41 141.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.16 001310283.1_25628001_3 - 1.1e-11 44.6 0.0 1e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.15 001310283.1_25628001_3 - 5.7e-11 41.9 0.8 2.8e-10 39.7 0.1 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.4 001310283.1_25628001_3 - 1.2e-08 35.2 0.2 0.0047 17.1 0.2 4.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.4 001310283.1_25628001_3 - 2.3e-08 34.4 0.0 0.0013 19.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.20 001310283.1_25628001_3 - 2.9e-07 30.7 0.0 0.025 14.8 0.0 3.2 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.10 001310283.1_25628001_3 - 3.5e-07 29.6 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.12 001310283.1_25628001_3 - 3.6e-07 30.3 0.0 2.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.4 001310283.1_25628001_3 - 2.1e-06 27.8 0.0 0.056 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.4 001310283.1_25628001_3 - 3.2e-06 27.1 0.0 0.047 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.12 001310283.1_25628001_3 - 3.6e-06 26.9 0.0 0.0013 18.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.4 001310283.1_25628001_3 - 4.1e-06 27.2 0.0 0.02 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.11 001310283.1_25628001_3 - 8.1e-06 24.9 0.0 0.077 11.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.19 001310283.1_25628001_3 - 2.7e-05 23.5 0.1 0.0052 16.1 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.15 001310283.1_25628001_3 - 8.1e-05 22.5 0.0 0.055 13.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.4 001310283.1_25628001_3 - 8.7e-05 22.2 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.16 001310283.1_25628001_3 - 0.00014 21.8 0.1 0.16 11.7 0.0 3.7 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea NACHT PF05729.10 001310283.1_25628001_3 - 0.00015 21.6 0.0 0.27 11.0 0.0 3.3 3 1 0 3 3 2 1 NACHT domain ABC_tran PF00005.25 001310283.1_25628001_3 - 0.0022 18.4 0.0 0.0081 16.5 0.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_28 PF13521.4 001310283.1_25628001_3 - 0.0026 17.9 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.4 001310283.1_25628001_3 - 0.0026 18.1 0.0 3 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.10 001310283.1_25628001_3 - 0.0086 15.3 0.0 2.9 7.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.15 001310283.1_25628001_3 - 0.0087 15.7 0.0 0.21 11.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.11 001310283.1_25628001_3 - 0.0095 15.2 0.1 0.078 12.2 0.0 2.3 2 1 1 3 3 3 1 KaiC AAA_3 PF07726.9 001310283.1_25628001_3 - 0.013 15.2 0.0 0.92 9.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.24 001310283.1_25628001_3 - 0.018 14.6 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.20 001310283.1_25628001_3 - 0.019 13.9 0.0 0.24 10.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.15 001310283.1_25628001_3 - 0.021 13.8 0.0 3 6.7 0.0 3.1 4 0 0 4 4 4 0 Parvovirus non-structural protein NS1 KTI12 PF08433.8 001310283.1_25628001_3 - 0.031 13.6 0.2 12 5.1 0.0 3.1 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_25 PF13481.4 001310283.1_25628001_3 - 0.032 13.7 0.2 2 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.4 001310283.1_25628001_3 - 0.067 12.8 0.0 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4939 PF16297.3 001291216.1_25629001_1 - 9.8e-16 57.5 0.0 1.7e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291216.1_25629001_1 - 2.2e-14 53.3 0.0 2.2e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein KASH_CCD PF14662.4 001291216.1_25629001_1 - 0.00051 19.8 2.8 0.00089 19.0 2.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291216.1_25629001_1 - 0.0016 18.0 0.2 0.0042 16.6 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291216.1_25629001_1 - 0.0038 17.0 0.3 0.0064 16.2 0.3 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 Rootletin PF15035.4 001291216.1_25629001_1 - 0.013 15.4 3.7 0.024 14.6 3.7 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.19 001291216.1_25629001_1 - 0.16 12.0 4.0 0.43 10.6 4.0 1.7 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 001291216.1_25629001_1 - 0.25 11.0 2.3 0.52 9.9 2.3 1.4 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.11 001291216.1_25629001_1 - 0.29 11.7 1.9 0.75 10.3 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CENP-H PF05837.10 001291216.1_25629001_1 - 0.39 11.0 4.3 1.2 9.5 4.3 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.10 001291216.1_25629001_1 - 0.42 11.1 4.5 1.1 9.8 4.5 1.7 1 0 0 1 1 1 0 SlyX ZapB PF06005.10 001291216.1_25629001_1 - 0.46 10.8 9.0 1 9.7 9.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB TolA_bind_tri PF16331.3 001291216.1_25629001_1 - 2.1 8.3 7.0 3.9 7.5 7.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation GIT_CC PF16559.3 001291216.1_25629001_1 - 2.7 8.0 6.3 9.6 6.2 6.3 1.9 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.13 001291216.1_25629001_1 - 3.3 7.4 6.4 8.1 6.2 6.4 1.6 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.16 001291216.1_25629001_1 - 6.5 7.0 6.0 22 5.3 6.0 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family Asp_protease_2 PF13650.4 001291216.1_25629001_3 - 0.002 18.6 0.0 0.0033 17.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.4 001291216.1_25629001_3 - 0.078 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.9 001291216.1_25629001_3 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Rer1 PF03248.11 001310239.1_25623001_1 - 9.8e-78 259.6 9.1 1.2e-77 259.3 9.1 1.1 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.7 001310239.1_25623001_1 - 2 7.8 8.6 0.09 12.2 0.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) TRF PF08558.8 001310285.1_25625001_3 - 1e-29 103.7 0.2 1.6e-29 103.1 0.2 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.29 001310285.1_25625001_3 - 4.8e-10 39.3 2.3 1.1e-09 38.1 2.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001310285.1_25625001_3 - 0.00027 21.0 3.1 0.00033 20.7 1.3 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Filament PF00038.19 001310297.1_25624001_2 - 1e-116 389.7 42.2 1.2e-116 389.5 42.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.3 001310297.1_25624001_2 - 3e-15 56.6 3.1 3e-15 56.6 3.1 2.1 2 0 0 2 2 2 1 Keratin type II head TPR_MLP1_2 PF07926.10 001310297.1_25624001_2 - 8.6e-05 22.5 2.8 8.6e-05 22.5 2.8 4.2 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.7 001310297.1_25624001_2 - 8.6e-05 22.4 38.1 0.0013 18.7 7.2 3.8 1 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.9 001310297.1_25624001_2 - 0.00093 18.0 39.2 0.069 11.9 14.0 3.1 1 1 1 2 2 2 2 Spc7 kinetochore protein ADIP PF11559.6 001310297.1_25624001_2 - 0.0017 18.3 27.2 0.012 15.6 8.3 3.6 2 2 0 3 3 3 2 Afadin- and alpha -actinin-Binding IncA PF04156.12 001310297.1_25624001_2 - 0.011 15.4 35.4 0.73 9.5 12.5 3.4 1 1 2 3 3 3 0 IncA protein DivIC PF04977.13 001310297.1_25624001_2 - 0.012 15.2 0.8 0.012 15.2 0.8 5.8 3 2 4 7 7 7 0 Septum formation initiator TolA_bind_tri PF16331.3 001310297.1_25624001_2 - 0.021 14.7 2.0 0.021 14.7 2.0 5.4 4 2 1 5 5 5 0 TolA binding protein trimerisation Taxilin PF09728.7 001310297.1_25624001_2 - 0.04 13.1 31.1 0.15 11.2 31.1 1.8 1 1 0 1 1 1 0 Myosin-like coiled-coil protein NT5C PF06941.10 001310297.1_25624001_2 - 0.042 13.6 0.2 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) PKcGMP_CC PF16808.3 001310297.1_25624001_2 - 0.076 12.7 8.2 7.1 6.4 0.4 4.9 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Alanine_zipper PF11839.6 001310297.1_25624001_2 - 0.089 12.9 7.3 0.39 10.9 7.3 2.1 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein CALCOCO1 PF07888.9 001310297.1_25624001_2 - 0.17 10.3 33.0 1.7 7.0 32.7 2.0 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.10 001310297.1_25624001_2 - 0.23 10.7 8.3 1.4 8.1 2.4 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein ABC_tran_CTD PF16326.3 001310297.1_25624001_2 - 0.3 11.2 33.9 0.025 14.7 8.3 4.5 3 2 1 4 4 3 0 ABC transporter C-terminal domain ATG16 PF08614.9 001310297.1_25624001_2 - 0.4 10.7 33.7 4 7.4 9.4 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.10 001310297.1_25624001_2 - 0.45 10.4 19.4 2.3 8.1 2.2 3.8 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Jnk-SapK_ap_N PF09744.7 001310297.1_25624001_2 - 0.79 9.8 33.8 0.4 10.8 7.4 3.5 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF1192 PF06698.9 001310297.1_25624001_2 - 1.2 9.1 13.3 1.5 8.8 1.4 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) CHDCT2 PF08074.9 001310297.1_25624001_2 - 1.3 9.0 17.6 0.33 11.0 5.6 2.6 1 1 0 2 2 2 0 CHDCT2 (NUC038) domain DUF4407 PF14362.4 001310297.1_25624001_2 - 1.4 8.1 23.7 98 2.0 2.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.10 001310297.1_25624001_2 - 1.5 8.7 21.4 0.37 10.6 1.3 4.6 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) COG5 PF10392.7 001310297.1_25624001_2 - 1.5 8.8 10.9 0.45 10.6 1.6 3.5 1 1 2 3 3 3 0 Golgi transport complex subunit 5 COMP PF11598.6 001310297.1_25624001_2 - 1.6 9.1 4.6 6.9 7.1 0.9 3.0 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein BRE1 PF08647.9 001310297.1_25624001_2 - 2 8.4 36.4 0.15 12.0 7.3 4.5 1 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase GAS PF13851.4 001310297.1_25624001_2 - 2.6 7.2 38.9 0.11 11.8 8.0 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3138 PF11336.6 001310297.1_25624001_2 - 2.6 6.4 4.4 4.6 5.6 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF5082 PF16888.3 001310297.1_25624001_2 - 4 7.7 32.6 0.099 12.9 4.2 4.5 2 2 2 4 4 4 0 Domain of unknown function (DUF5082) DUF1451 PF07295.9 001310297.1_25624001_2 - 8.6 6.3 15.2 5.1 7.0 2.5 2.7 2 1 0 2 2 2 0 Zinc-ribbon containing domain zf-RING_2 PF13639.4 001310274.1_25626001_2 - 9.2e-09 35.3 15.4 3.8e-08 33.3 15.4 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.4 001310274.1_25626001_2 - 1.6e-08 34.1 10.0 1.6e-08 34.1 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001310274.1_25626001_2 - 3.5e-07 29.8 10.7 1.1e-06 28.3 10.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.23 001310274.1_25626001_2 - 4.4e-06 26.3 13.9 4.4e-06 26.3 13.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001310274.1_25626001_2 - 1.5e-05 24.6 13.8 1.5e-05 24.6 13.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001310274.1_25626001_2 - 0.00038 20.5 11.0 0.00038 20.5 11.0 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.4 001310274.1_25626001_2 - 0.00065 19.5 11.3 0.00065 19.5 11.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001310274.1_25626001_2 - 0.00068 19.5 12.7 0.00069 19.5 9.0 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001310274.1_25626001_2 - 0.033 14.2 11.7 0.09 12.8 11.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.5 001310274.1_25626001_2 - 0.12 12.3 4.5 0.36 10.8 4.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.3 001310274.1_25626001_2 - 1.3 9.1 7.8 3.4 7.8 7.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.3 001310274.1_25626001_2 - 2.2 7.9 5.9 7.3 6.3 4.8 2.5 2 0 0 2 2 2 0 RING-like zinc finger Pex2_Pex12 PF04757.12 001310274.1_25626001_3 - 1.2e-37 129.5 4.3 1.7e-37 129.1 4.3 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region TROVE PF05731.9 001310313.1_25629001_1 - 4.8e-127 424.1 1.6 7.8e-127 423.4 1.6 1.3 1 0 0 1 1 1 1 TROVE domain TEP1_N PF05386.9 001310313.1_25629001_1 - 3.5e-49 163.9 8.1 8e-18 63.6 0.8 3.8 3 0 0 3 3 3 3 TEP1 N-terminal domain WD40 PF00400.30 001310313.1_25629001_1 - 2.2e-42 142.1 44.1 1.7e-05 25.3 0.1 17.4 18 0 0 18 18 16 9 WD domain, G-beta repeat NACHT PF05729.10 001310313.1_25629001_1 - 3.9e-32 111.3 0.2 1.1e-31 109.9 0.2 1.8 1 0 0 1 1 1 1 NACHT domain DUF4062 PF13271.4 001310313.1_25629001_1 - 8e-18 64.5 0.0 1.9e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) ANAPC4_WD40 PF12894.5 001310313.1_25629001_1 - 5.5e-13 48.9 0.4 0.14 12.3 0.0 7.7 7 1 1 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001310313.1_25629001_1 - 9.8e-08 31.2 0.0 0.11 11.3 0.0 5.0 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.4 001310313.1_25629001_1 - 2.6e-06 27.8 0.5 8.6e-06 26.1 0.5 1.9 1 0 0 1 1 1 1 AAA ATPase domain WD40_like PF17005.3 001310313.1_25629001_1 - 4.9e-06 25.9 0.0 0.0031 16.7 0.0 3.3 3 0 0 3 3 3 1 WD40-like domain AAA_22 PF13401.4 001310313.1_25629001_1 - 4.2e-05 23.7 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Nup160 PF11715.6 001310313.1_25629001_1 - 0.00079 18.0 0.6 1 7.8 0.1 3.8 4 0 0 4 4 4 2 Nucleoporin Nup120/160 AAA_25 PF13481.4 001310313.1_25629001_1 - 0.0048 16.4 0.2 0.014 14.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain Frtz PF11768.6 001310313.1_25629001_1 - 0.0054 15.0 0.0 0.87 7.7 0.0 2.6 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz AAA_19 PF13245.4 001310313.1_25629001_1 - 0.01 16.0 0.0 0.051 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.4 001310313.1_25629001_1 - 0.013 15.0 0.1 0.035 13.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.4 001310313.1_25629001_1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PQQ_3 PF13570.4 001310313.1_25629001_1 - 0.065 13.6 2.1 29 5.2 0.0 4.8 4 1 0 4 4 4 0 PQQ-like domain T2SSE PF00437.18 001310313.1_25629001_1 - 0.079 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.21 001310313.1_25629001_1 - 0.14 12.1 0.3 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SH3_2 PF07653.15 001305106.1_25625001_1 - 1.1e-34 117.7 0.5 2.1e-13 49.6 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.4 001305106.1_25625001_1 - 1.9e-32 110.7 0.3 7.2e-12 44.8 0.0 3.5 3 1 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.26 001305106.1_25625001_1 - 3.8e-31 106.3 0.1 2.1e-10 39.9 0.0 3.4 3 0 0 3 3 3 3 SH3 domain zf-C3HC4 PF00097.23 001305106.1_25625001_1 - 4.2e-09 36.0 10.8 7.5e-09 35.2 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001305106.1_25625001_1 - 8.5e-09 35.0 11.7 1.7e-08 34.0 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001305106.1_25625001_1 - 2e-08 34.2 10.1 3.7e-08 33.4 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.4 001305106.1_25625001_1 - 2e-08 34.0 9.4 4.9e-08 32.7 9.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 001305106.1_25625001_1 - 4.9e-08 32.6 7.4 9.4e-08 31.7 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001305106.1_25625001_1 - 4.1e-07 29.7 10.3 7e-07 29.0 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.4 001305106.1_25625001_1 - 6.6e-05 22.4 8.1 0.00014 21.4 8.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.4 001305106.1_25625001_1 - 0.0021 18.0 9.9 0.0042 17.1 9.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.4 001305106.1_25625001_1 - 0.0043 16.7 9.8 0.02 14.6 10.1 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.3 001305106.1_25625001_1 - 0.17 11.5 7.3 0.05 13.2 3.7 2.0 1 1 1 2 2 2 0 RING-like zinc finger DUF1272 PF06906.9 001305106.1_25625001_1 - 0.56 10.2 5.0 1.1 9.2 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-MYND PF01753.16 001305106.1_25625001_1 - 0.75 9.8 3.4 1.9 8.5 3.4 1.7 1 1 0 1 1 1 0 MYND finger zf-MIZ PF02891.18 001305106.1_25625001_1 - 0.9 9.2 8.3 2 8.1 8.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.5 001305106.1_25625001_1 - 2.9 8.1 7.8 6.3 7.0 7.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zinc-ribbons_6 PF07191.10 001305106.1_25625001_1 - 3.2 7.7 8.0 5.6 6.9 8.0 1.3 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.5 001305106.1_25625001_1 - 3.4 7.6 9.3 7.6 6.5 9.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon Trm112p PF03966.14 001305106.1_25625001_1 - 4.5 7.8 5.0 12 6.4 5.0 1.8 1 0 0 1 1 1 0 Trm112p-like protein zf-Nse PF11789.6 001305106.1_25625001_1 - 9.2 6.0 8.0 21 4.9 8.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.9 001305106.1_25625001_1 - 9.6 6.5 7.7 20 5.5 7.7 1.6 1 0 0 1 1 1 0 RING-like domain Crystallin PF00525.16 001279857.2_25622001_3 - 1.4e-29 101.9 5.7 2.5e-29 101.1 5.7 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.19 001279857.2_25622001_3 - 1.5e-24 85.9 0.1 1.9e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family SSrecog PF03531.12 001310301.1_25626001_3 - 1e-87 292.9 0.0 1.9e-87 292.1 0.0 1.5 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.10 001310301.1_25626001_3 - 2.5e-27 95.0 0.1 2.5e-26 91.8 0.1 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HMG_box PF00505.17 001310301.1_25626001_3 - 3.6e-24 84.8 5.8 1.1e-23 83.2 5.8 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001310301.1_25626001_3 - 4.1e-12 46.4 4.3 4.1e-12 46.4 4.3 2.3 2 0 0 2 2 2 1 HMG-box domain Orn_Arg_deC_N PF02784.14 001293743.1_25627001_1 - 6e-70 235.3 0.1 7.8e-70 235.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293743.1_25627001_1 - 8.5e-19 67.6 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293743.1_25627001_1 - 0.00037 19.9 0.0 0.00072 18.9 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF846 PF05832.10 001281982.1_25625001_3 - 1.5e-54 183.7 9.9 1.5e-54 183.7 9.9 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF846) P53 PF00870.16 001310270.1_25625001_1 - 6e-113 375.1 1.0 8e-113 374.7 1.0 1.1 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.9 001310270.1_25625001_1 - 2.8e-17 61.6 3.2 6.2e-17 60.5 3.2 1.6 1 0 0 1 1 1 1 P53 tetramerisation motif P53_TAD PF08563.9 001310270.1_25625001_1 - 2.4e-13 49.0 4.3 4.9e-13 48.0 4.3 1.6 1 0 0 1 1 1 1 P53 transactivation motif DEC-1_N PF04625.11 001310270.1_25625001_1 - 0.36 9.7 3.3 0.51 9.2 3.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region LRR_9 PF14580.4 001282106.1_25622001_1 - 2.2e-12 46.7 0.0 1e-11 44.5 0.0 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.4 001282106.1_25622001_1 - 1.1e-06 28.1 3.2 1.1e-06 28.1 3.2 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282106.1_25622001_1 - 1.9e-06 28.0 8.2 0.012 15.9 0.3 3.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001282106.1_25622001_1 - 1.2 9.8 7.8 62 4.5 0.3 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat IL1 PF00340.17 001280620.1_52224001_2 - 6.6e-33 112.8 0.0 8.7e-33 112.4 0.0 1.2 1 0 0 1 1 1 1 Interleukin-1 / 18 Peptidase_M1 PF01433.18 001282364.1_11324001_1 - 4.5e-78 263.1 0.0 6e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.9 001282364.1_11324001_1 - 7.6e-45 152.3 0.6 1.3e-44 151.5 0.6 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal E1_DerP2_DerF2 PF02221.13 001282364.1_11324001_1 - 0.026 14.8 0.1 0.05 13.9 0.1 1.4 1 0 0 1 1 1 0 ML domain Peptidase_C58 PF03543.12 001282364.1_11324001_1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Peptidase_M48 PF01435.16 001282364.1_11324001_1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M48 G-alpha PF00503.18 073434.1_49824120_1 - 1e-99 333.9 0.2 1.3e-99 333.6 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 073434.1_49824120_1 - 1e-13 51.0 0.8 3.1e-13 49.4 0.5 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.11 073434.1_49824120_1 - 0.034 14.2 0.9 0.096 12.8 0.2 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.18 033292.2_49824120_1 - 1.2e-100 337.0 0.2 1.5e-100 336.7 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 033292.2_49824120_1 - 1.6e-13 50.3 1.5 3.1e-13 49.4 0.5 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.11 033292.2_49824120_1 - 0.022 14.8 0.9 0.096 12.8 0.2 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.18 033291.2_49824120_1 - 1.2e-97 327.1 0.0 1.6e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 033291.2_49824120_1 - 1.3e-13 50.7 1.0 3.3e-13 49.3 0.5 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.11 033291.2_49824120_1 - 0.041 14.0 0.5 0.1 12.7 0.2 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Casein_kappa PF00997.16 001290972.1_07322001_1 - 2.2e-71 239.0 17.8 2.8e-71 238.6 17.8 1.1 1 0 0 1 1 1 1 Kappa casein 7tm_1 PF00001.19 001310165.1_33423001_1 - 5.4e-50 170.0 12.1 6.7e-50 169.7 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.7 001310165.1_33423001_1 - 3.1e-11 43.0 8.7 8.3e-11 41.6 8.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.7 001310165.1_33423001_1 - 4.3e-07 29.4 7.0 7e-07 28.7 6.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.7 001310165.1_33423001_1 - 6.2e-07 28.9 12.7 9e-07 28.4 12.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001310165.1_33423001_1 - 3.5e-05 23.6 8.9 0.00041 20.1 3.2 2.4 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001310165.1_33423001_1 - 0.00016 21.0 4.9 0.00016 21.0 4.9 2.1 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Hormone_6 PF00236.16 001308524.1_02621001_1 - 1.9e-49 165.5 12.9 2.2e-49 165.3 12.9 1.0 1 0 0 1 1 1 1 Glycoprotein hormone PDGF PF00341.15 001308524.1_02621001_1 - 0.03 14.5 10.8 0.046 13.9 10.8 1.3 1 0 0 1 1 1 0 PDGF/VEGF domain Cys_knot PF00007.20 001308522.1_02621001_1 - 2.5e-29 101.5 6.4 3.1e-29 101.2 6.4 1.1 1 0 0 1 1 1 1 Cystine-knot domain Interferon PF00143.17 001310172.2_33422001_1 - 3.4e-54 183.2 0.0 3.9e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain ubiquitin PF00240.21 001310172.2_33422001_1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family BCNT PF07572.10 001319876.1_08523001_1 - 2.7e-31 107.3 0.7 1e-30 105.5 0.7 2.0 1 0 0 1 1 1 1 Bucentaur or craniofacial development Cys_knot PF00007.20 001304859.1_01321001_1 - 4.8e-33 113.5 2.5 5.5e-33 113.3 2.5 1.0 1 0 0 1 1 1 1 Cystine-knot domain Globin PF00042.20 001286598.3_40023001_1 - 3.3e-21 75.8 1.8 4.6e-21 75.3 1.8 1.2 1 0 0 1 1 1 1 Globin Aldo_ket_red PF00248.19 145511.1_49823120_3 - 2.9e-52 177.5 0.0 3.2e-51 174.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.20 132429.1_49823120_1 - 0.034 12.8 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 p450 PF00067.20 132429.1_49823120_2 - 2.4e-15 56.1 0.1 2.8e-07 29.5 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 Semenogelin PF05474.9 038076.2_29624120_1 - 5e-124 414.9 25.7 6.3e-124 414.5 25.7 1.0 1 0 0 1 1 1 1 Semenogelin Destabilase PF05497.10 038076.2_29624120_1 - 0.1 12.8 1.4 0.19 11.9 1.4 1.3 1 0 0 1 1 1 0 Destabilase Semenogelin PF05474.9 038076.2_29624120_2 - 2.2e-99 333.5 46.8 3.1e-99 333.0 46.8 1.1 1 0 0 1 1 1 1 Semenogelin FlgH PF02107.14 038076.2_29624120_3 - 0.037 13.5 0.0 4.5 6.7 0.0 2.9 3 0 0 3 3 3 0 Flagellar L-ring protein TRIC PF05197.11 001190164.1_49823001_2 - 1.5e-77 259.3 3.5 2e-77 258.9 3.5 1.2 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.11 001190164.1_49823001_2 - 0.0036 17.2 0.2 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 UPF0126 domain ODC_AZ PF02100.15 001289802.1_52222001_3 - 3.2e-20 72.1 0.0 5.3e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme 7tm_4 PF13853.4 001000999.1_45722001_1 - 2.1e-51 175.1 24.8 2.6e-51 174.9 24.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000999.1_45722001_1 - 1.6e-22 79.9 25.9 2.8e-22 79.1 25.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_transf_6 PF03414.11 132143.2_24228120_1 - 5.7e-39 133.6 0.2 7.7e-39 133.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_transf_6 PF03414.11 132143.2_24228120_2 - 6.3e-53 179.5 1.3 6.3e-53 179.5 1.3 1.9 1 1 1 2 2 2 2 Glycosyltransferase family 6 Glyco_transf_6 PF03414.11 132147.2_29625120_2 - 1.4e-99 332.8 1.5 1.8e-99 332.4 1.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 Calpain_inhib PF00748.17 001009788.1_39526001_1 - 5.5e-103 340.6 122.5 1.3e-34 119.3 9.1 7.1 5 1 1 6 6 6 4 Calpain inhibitor Maf_N PF08383.9 001009788.1_39526001_1 - 0.011 15.4 0.3 2.8 7.7 0.1 2.7 2 0 0 2 2 2 0 Maf N-terminal region zf-CCHC_5 PF14787.4 001009788.1_39526001_1 - 0.91 9.1 6.5 6.9 6.3 0.1 3.5 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger TMEM174 PF15029.4 001132669.2_43523001_1 - 1e-117 391.8 0.6 1.3e-117 391.5 0.6 1.1 1 0 0 1 1 1 1 Transmembrane protein 174 PTE PF02126.16 001133311.1_43524001_2 - 7.9e-133 442.3 0.0 9.4e-133 442.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family TatD_DNase PF01026.19 001133311.1_43524001_2 - 6.4e-05 22.3 0.0 8.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase NESP55 PF06390.10 001132300.2_43525001_1 - 0.0014 18.2 2.9 0.0029 17.1 2.9 1.5 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) Fip1 PF05182.11 001132300.2_43525001_3 - 2e-25 87.9 2.1 6.2e-25 86.3 2.1 1.9 1 0 0 1 1 1 1 Fip1 motif zf-C4 PF00105.16 001082726.1_37924001_3 - 1.3e-28 99.1 14.3 1.3e-28 99.1 14.3 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001082726.1_37924001_3 - 4e-25 88.5 0.8 4e-25 88.5 0.8 2.0 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor FAM110_N PF14161.4 001133233.1_43527001_3 - 1.9e-46 156.8 2.6 3.4e-46 156.0 2.6 1.4 1 0 0 1 1 1 1 Centrosome-associated N terminus FAM110_C PF14160.4 001133233.1_43527001_3 - 4.5e-33 114.5 0.3 1.1e-32 113.2 0.3 1.7 1 0 0 1 1 1 1 Centrosome-associated C terminus GCFC PF07842.10 001133272.1_43526001_3 - 2.1e-100 335.8 17.1 3.3e-100 335.1 14.1 2.1 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.6 001133272.1_43526001_3 - 1.6e-29 102.2 10.2 1.6e-29 102.2 10.2 2.0 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.21 001133272.1_43526001_3 - 1.7e-16 59.7 4.5 3.2e-16 58.9 4.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.5 001133272.1_43526001_3 - 0.0002 21.3 1.1 0.00048 20.0 1.1 1.7 1 0 0 1 1 1 1 G-patch domain 7tm_1 PF00001.19 001185041.1_08023001_1 - 2e-51 174.7 23.4 7.4e-51 172.8 23.8 1.8 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001185041.1_08023001_1 - 2.1e-09 37.0 21.4 2.6e-09 36.7 21.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UPF0233 PF06781.10 001185041.1_08023001_1 - 0.61 10.0 3.0 1.1 9.3 0.0 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) Ank_2 PF12796.5 001204919.1_08029001_3 - 6.2e-150 488.1 36.7 4e-19 68.9 0.6 12.3 3 3 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001204919.1_08029001_3 - 1.9e-119 388.5 17.3 9.1e-10 38.8 0.1 16.0 8 3 7 17 17 17 16 Ankyrin repeats (many copies) Ank PF00023.28 001204919.1_08029001_3 - 3.4e-112 362.3 50.9 5e-08 32.9 0.0 24.6 24 0 0 24 24 24 23 Ankyrin repeat Ank_3 PF13606.4 001204919.1_08029001_3 - 1.9e-102 322.6 28.8 6.4e-05 22.9 0.0 25.5 25 0 0 25 25 25 23 Ankyrin repeat Ank_5 PF13857.4 001204919.1_08029001_3 - 7.7e-98 318.7 46.6 5.4e-08 32.9 0.0 20.9 5 3 15 21 21 21 20 Ankyrin repeats (many copies) KH_1 PF00013.27 001204919.1_08029001_3 - 1.1e-14 53.9 0.6 2.9e-14 52.5 0.6 1.8 1 0 0 1 1 1 1 KH domain S10_plectin PF03501.13 001193579.1_29622001_1 - 3.5e-50 167.9 0.2 4.3e-50 167.6 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain eIF_4EBP PF05456.9 001205007.1_08022001_3 - 1.2e-37 128.2 1.5 1.6e-37 127.8 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Somatostatin PF03002.13 001204927.1_08023001_3 - 2.3e-09 36.9 7.5 4.3e-09 36.0 7.5 1.5 1 0 0 1 1 1 1 Somatostatin/Cortistatin family RnaseA PF00074.18 001270922.1_08023001_2 - 6.9e-32 110.4 0.4 1e-31 109.9 0.4 1.2 1 0 0 1 1 1 1 Pancreatic ribonuclease UQ_con PF00179.24 001205089.1_08022001_3 - 1.2e-17 63.7 0.0 1.6e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001205089.1_08022001_3 - 0.091 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ribonuclease_T2 PF00445.16 001266725.1_29623001_1 - 2.5e-65 220.0 1.6 3.5e-65 219.5 1.6 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DHODB_Fe-S_bind PF10418.7 001266725.1_29623001_1 - 0.012 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Integrin_alpha2 PF08441.10 001265953.1_29629001_1 - 1.8e-121 406.2 0.0 2.1e-121 405.9 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 001265953.1_29629001_1 - 1.3e-27 95.4 25.0 1.7e-07 31.1 3.0 4.8 4 0 0 4 4 4 4 FG-GAP repeat VCBS PF13517.4 001265953.1_29629001_1 - 6.4e-14 52.2 13.3 7.4e-05 23.1 0.2 4.5 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001265953.1_29629001_1 - 0.00014 21.5 0.7 0.00029 20.5 0.7 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.3 001265953.1_29629001_1 - 0.00053 19.5 0.0 0.00077 19.0 0.0 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family RNase_H PF00075.22 001285495.1_08023001_1 - 1.5e-44 151.5 0.0 2.2e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285495.1_08023001_1 - 2.4e-19 69.2 1.2 4.4e-19 68.4 1.2 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285495.1_08023001_1 - 0.0028 17.2 0.0 0.0058 16.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase-like Rdx PF10262.7 001278377.1_08022001_2 - 5.2e-08 32.8 0.1 1.6e-07 31.3 0.1 1.8 1 1 0 1 1 1 1 Rdx family Insulin PF00049.16 001285579.1_09021001_1 - 4.9e-06 27.3 4.1 5.4e-05 24.0 4.1 2.0 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001285579.1_09021001_1 - 0.0049 16.7 2.1 0.35 10.8 0.2 2.2 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type ODR4-like PF14778.4 001260697.2_29624001_1 - 1.4e-118 395.9 0.2 1.7e-118 395.7 0.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like Ribosomal_S19 PF00203.19 001265922.1_29622001_1 - 2.1e-40 136.3 0.4 3e-40 135.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Prok_Ub PF14454.4 001265922.1_29622001_1 - 0.026 14.0 0.1 0.063 12.8 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin MAP65_ASE1 PF03999.10 001265922.1_29622001_1 - 0.04 12.5 1.0 0.049 12.2 1.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Hormone_recep PF00104.28 001267749.2_08026001_1 - 5.2e-30 104.4 6.8 8.8e-30 103.7 6.8 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001267749.2_08026001_1 - 6.9e-26 90.4 14.4 1.3e-25 89.5 14.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CAP_N PF01213.17 001267749.2_08026001_1 - 4 6.7 6.2 8.5 5.6 6.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SAM_1 PF00536.28 001267763.1_08029001_1 - 9.4e-21 73.9 0.1 1.7e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_2 PF12796.5 001267763.1_08029001_1 - 1.5e-20 73.5 4.3 1.8e-09 37.9 0.6 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001267763.1_08029001_1 - 2.2e-15 56.7 7.9 4.5e-07 30.2 0.3 5.9 1 1 5 6 6 6 5 Ankyrin repeats (many copies) SAM_2 PF07647.15 001267763.1_08029001_1 - 7.1e-13 48.3 0.1 1.3e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FERM_f0 PF16511.3 001267763.1_08029001_1 - 9.8e-12 44.9 0.0 1.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM SH3_2 PF07653.15 001267763.1_08029001_1 - 2.1e-11 43.2 0.2 4.9e-11 42.0 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.4 001267763.1_08029001_1 - 1.5e-10 41.0 8.3 0.00066 19.9 0.5 4.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.28 001267763.1_08029001_1 - 8.4e-09 35.4 12.6 0.0011 19.2 0.0 5.7 6 0 0 6 6 5 3 Ankyrin repeat SH3_9 PF14604.4 001267763.1_08029001_1 - 2.1e-08 33.7 0.0 4.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.4 001267763.1_08029001_1 - 2.3e-08 33.5 5.6 0.58 10.8 0.0 6.8 7 0 0 7 7 6 2 Ankyrin repeat PDZ PF00595.22 001267763.1_08029001_1 - 1.3e-06 28.5 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_1 PF00018.26 001267763.1_08029001_1 - 2.2e-05 23.9 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Tektin PF03148.12 001285262.1_29524001_2 - 3.6e-139 463.6 27.8 4.1e-139 463.4 27.8 1.0 1 0 0 1 1 1 1 Tektin family Exonuc_VII_L PF02601.13 001285262.1_29524001_2 - 2.1 7.7 14.0 0.33 10.3 4.1 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Lzipper-MIP1 PF14389.4 001285262.1_29524001_2 - 2.3 8.4 11.4 0.16 12.1 0.8 3.6 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Laminin_II PF06009.10 001285262.1_29524001_2 - 2.6 7.9 9.4 1.5 8.7 0.9 3.2 4 1 0 4 4 4 0 Laminin Domain II PID PF00640.21 001266317.1_29626001_2 - 0.014 15.3 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Zona_pellucida PF00100.21 001267734.2_08024001_2 - 2.3e-55 188.0 0.4 7.6e-55 186.3 0.3 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain Trefoil PF00088.16 001267734.2_08024001_2 - 1.5e-10 40.6 6.5 4.4e-10 39.1 6.5 1.9 1 0 0 1 1 1 1 Trefoil (P-type) domain DUF846 PF05832.10 001281865.1_08023001_3 - 5.8e-55 185.0 9.8 8.1e-55 184.5 9.8 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF3169 PF11368.6 001281865.1_08023001_3 - 0.026 14.0 1.7 0.38 10.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) HXXEE PF13787.4 001281865.1_08023001_3 - 2.8 8.6 7.7 4.1 8.1 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif CD34_antigen PF06365.10 001267735.1_08023001_1 - 1.1e-70 237.4 0.0 1.6e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF4064 PF13273.4 001267735.1_08023001_1 - 0.011 16.0 0.6 0.027 14.7 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) PAP1 PF08601.8 001267735.1_08023001_1 - 8.7 5.8 19.4 3.2 7.2 13.7 2.0 2 0 0 2 2 2 0 Transcription factor PAP1 MMADHC PF10229.7 001285614.1_09022001_1 - 5.8e-132 439.3 0.0 6.6e-132 439.1 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein MHC_II_beta PF00969.17 001267731.1_08022001_1 - 1.5e-39 133.9 1.0 2.2e-39 133.3 1.0 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001267731.1_08022001_1 - 1.6e-24 86.1 0.2 2.9e-24 85.2 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.23 001267731.1_08022001_1 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001267731.1_08022001_1 - 0.00019 21.9 0.4 0.0004 20.8 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin domain DUF202 PF02656.13 001267731.1_08022001_1 - 0.074 13.4 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Trypsin PF00089.24 001290979.1_07323001_2 - 2.9e-54 184.1 0.1 3.8e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 Trypsin Sushi PF00084.18 001290979.1_07323001_2 - 0.026 15.0 4.0 2.2 8.8 0.7 3.0 2 1 0 2 2 2 0 Sushi repeat (SCR repeat) TLV_coat PF00429.17 001316726.1_36523001_1 - 2.7e-10 39.4 8.2 3e-10 39.3 1.2 2.6 2 1 0 2 2 2 2 ENV polyprotein (coat polyprotein) GP41 PF00517.15 001316726.1_36523001_1 - 4.4e-05 23.3 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 Retroviral envelope protein Baculo_F PF12259.6 001316726.1_36523001_1 - 0.048 12.1 0.6 0.075 11.4 0.6 1.2 1 0 0 1 1 1 0 Baculovirus F protein TMEM52 PF14979.4 001316726.1_36523001_1 - 4.7 7.0 6.7 8.7 6.1 6.7 1.3 1 0 0 1 1 1 0 Transmembrane 52 Ldh_1_N PF00056.21 001310281.1_25624001_1 - 9.7e-51 171.4 0.7 1.4e-50 170.9 0.7 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001310281.1_25624001_1 - 5.2e-23 81.7 0.0 8.9e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.14 001310281.1_25624001_1 - 0.031 13.7 0.8 0.074 12.5 0.0 2.0 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Pyr_redox_2 PF07992.12 001310281.1_25624001_1 - 0.052 12.7 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.14 001310305.1_25627001_2 - 2.4e-34 118.7 28.9 8.4e-32 110.3 24.0 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily CbtA PF09490.8 001310305.1_25627001_2 - 0.87 9.2 4.9 0.47 10.1 0.7 2.4 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) V-set PF07686.15 001302787.1_08023001_3 - 0.041 13.9 0.3 0.069 13.2 0.3 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain Macro PF01661.19 001310271.1_25624001_1 - 3.5e-26 91.4 0.1 5.7e-26 90.7 0.1 1.3 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.3 001310271.1_25624001_1 - 3.8e-17 61.6 0.8 1.2e-16 60.0 0.8 1.9 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.22 001310271.1_25624001_1 - 2.1e-12 47.5 0.0 2.1e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001310271.1_25624001_1 - 0.003 17.7 0.0 0.0082 16.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IRF-3 PF10401.7 001320278.1_44824001_1 - 2.9e-48 163.9 0.0 4e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.15 001320278.1_44824001_1 - 2.6e-36 123.9 0.0 7.9e-36 122.4 0.0 1.8 2 0 0 2 2 2 1 Interferon regulatory factor transcription factor TLV_coat PF00429.17 001305586.1_20324001_1 - 1.7e-31 109.4 1.4 1.8e-30 106.0 0.2 2.4 2 1 1 3 3 3 2 ENV polyprotein (coat polyprotein) CBP_BcsN PF17038.3 001305586.1_20324001_1 - 0.18 10.9 0.1 0.18 10.9 0.1 1.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsN CUB PF00431.18 001290873.1_07326001_1 - 2.4e-190 620.0 5.9 2.2e-40 137.3 0.1 5.2 5 0 0 5 5 5 5 CUB domain Astacin PF01400.22 001290873.1_07326001_1 - 2.1e-69 232.9 0.0 3.6e-69 232.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.4 001290873.1_07326001_1 - 1.8e-18 66.4 28.8 9.5e-10 38.5 9.1 3.2 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.13 001290873.1_07326001_1 - 1.9e-13 50.3 26.0 1.7e-07 31.2 5.5 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.5 001290873.1_07326001_1 - 6.5e-11 41.8 9.0 5.2e-06 26.2 1.7 3.4 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.25 001290873.1_07326001_1 - 1.3e-05 25.3 20.6 0.0064 16.6 6.9 3.0 2 0 0 2 2 2 2 EGF-like domain EGF_3 PF12947.5 001290873.1_07326001_1 - 3.5e-05 23.8 20.1 0.0013 18.7 4.6 3.1 2 1 1 3 3 3 2 EGF domain hEGF PF12661.5 001290873.1_07326001_1 - 8e-05 23.0 16.6 0.014 15.9 3.7 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF CUB_2 PF02408.18 001290873.1_07326001_1 - 0.00066 19.3 5.1 6.5 6.4 0.3 5.4 5 1 0 5 5 5 1 CUB-like domain Peptidase_M10 PF00413.22 001290873.1_07326001_1 - 0.0017 18.1 0.1 0.49 10.1 0.0 2.5 2 0 0 2 2 2 1 Matrixin EGF_MSP1_1 PF12946.5 001290873.1_07326001_1 - 0.018 14.9 15.1 0.2 11.6 6.3 2.8 2 0 0 2 2 2 0 MSP1 EGF domain 1 Reprolysin_4 PF13583.4 001290873.1_07326001_1 - 0.048 13.2 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Plasmod_Pvs28 PF06247.9 001290873.1_07326001_1 - 0.22 11.7 15.0 1.2 9.3 1.4 2.9 2 0 0 2 2 2 0 Pvs28 EGF domain DUF498 PF04430.12 001194523.1_29623001_2 - 4.2e-32 110.3 0.0 6e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) MHC_II_alpha PF00993.18 001314188.1_09022001_1 - 1.6e-36 123.7 0.2 2.2e-36 123.3 0.2 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001314188.1_09022001_1 - 3.8e-27 93.3 0.1 1.1e-26 91.9 0.1 1.8 1 0 0 1 1 1 1 C1-set C-terminal domain C1-set PF07654.13 001314188.1_09022001_1 - 2.3e-22 79.1 0.0 3.4e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001314188.1_09022001_1 - 4.8e-05 23.8 0.0 8.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.13 001314188.1_09022001_1 - 0.022 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A Globin PF00042.20 001310269.1_25623001_2 - 4.6e-14 52.8 0.0 6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Globin APOBEC_N PF08210.9 001292076.2_11723001_1 - 3.7e-86 287.4 4.1 5.1e-46 156.7 0.3 2.0 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001292076.2_11723001_1 - 5.2e-62 205.6 0.0 5.3e-30 103.1 0.0 2.7 2 0 0 2 2 2 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001292076.2_11723001_1 - 0.00014 21.5 0.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.4 001292076.2_11723001_1 - 0.0029 17.6 0.3 0.94 9.4 0.5 2.2 2 0 0 2 2 2 2 The BURPS668_1122 family of deaminases Pox_A3L PF05288.9 001292076.2_11723001_1 - 0.067 13.0 0.3 1.5 8.7 0.0 2.7 2 1 1 3 3 3 0 Poxvirus A3L Protein NODP PF07684.10 001292076.2_11723001_1 - 0.6 10.1 4.4 1.1 9.3 1.0 2.2 2 0 0 2 2 2 0 NOTCH protein RRM_1 PF00076.20 029425.1_32925120_2 - 7.2e-23 80.1 0.1 1.1e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM1CTR PF08081.9 029425.1_32925120_2 - 3e-22 78.3 12.2 3e-22 78.3 12.2 5.4 4 2 1 5 5 5 1 RBM1CTR (NUC064) family RRM_7 PF16367.3 029425.1_32925120_2 - 0.0069 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.4 029425.1_32925120_2 - 0.054 13.0 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 029425.1_32925120_2 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Cauli_VI PF01693.14 104352.1_08023120_1 - 2.2e-19 69.3 1.2 4.4e-19 68.4 1.2 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RNase_H PF00075.22 104352.1_08023120_1 - 3.2e-09 37.0 0.0 5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 RNase H RNase_H PF00075.22 104352.1_08023120_3 - 2.4e-26 92.5 0.1 3.5e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 RNase H ODC_AZ PF02100.15 125743.1_08025120_1 - 2.1e-19 69.4 0.0 4.1e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 125741.1_08025120_2 - 2.3e-19 69.4 0.0 4.4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme TIR PF01582.18 120680.1_49824120_2 - 3.9e-31 108.1 0.2 5.7e-31 107.5 0.2 1.1 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.4 120680.1_49824120_2 - 3e-06 27.3 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.9 120680.1_49824120_2 - 0.00014 22.1 0.1 0.00027 21.1 0.1 1.4 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_8 PF13855.4 120680.1_49824120_3 - 1.5e-06 27.7 0.3 2.7e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.31 120680.1_49824120_3 - 0.0053 16.9 0.7 0.19 12.2 0.6 3.3 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_4 PF12799.5 120680.1_49824120_3 - 0.016 15.4 0.4 0.029 14.6 0.4 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) ODC_AZ PF02100.15 125744.1_08024120_3 - 2.1e-19 69.5 0.0 3.3e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 125742.1_08025120_1 - 2.2e-19 69.4 0.0 4.2e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Prenyltrans PF00432.19 145513.1_49824120_1 - 1.6e-66 219.5 12.1 1.4e-15 56.6 0.1 6.5 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.4 145513.1_49824120_1 - 0.18 10.8 0.0 13 4.6 0.0 2.2 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain HMG_box PF00505.17 001288.1_26225120_1 - 3.6e-08 33.6 1.8 4.4e-08 33.3 0.5 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001288.1_26225120_3 - 3.4e-08 33.8 2.9 6.4e-08 33.0 2.9 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.17 001288.1_26225120_3 - 2.3e-05 24.6 2.4 2.3e-05 24.6 2.4 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box WASH_WAHD PF11945.6 024540.1_26224120_1 - 1.6e-93 313.3 0.0 2.1e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex WASH_WAHD PF11945.6 024540.1_26224120_2 - 2.1e-12 47.1 0.0 3.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 WAHD domain of WASH complex SERTA PF06031.11 030735.1_32922120_2 - 6.8e-14 51.1 2.8 1.1e-13 50.5 2.8 1.3 1 0 0 1 1 1 1 SERTA motif UPF0730 PF15827.3 030735.1_32922120_2 - 2.2e-11 43.6 2.8 3.8e-11 42.9 2.8 1.4 1 0 0 1 1 1 1 UPF0730 unknown protein family Hormone_1 PF00103.18 110935.1_08022120_1 - 1.1e-27 97.1 0.4 1.5e-27 96.7 0.4 1.2 1 0 0 1 1 1 1 Somatotropin hormone family Hormone_1 PF00103.18 110935.1_08022120_3 - 1.1e-06 28.4 1.0 1.4e-06 28.1 1.0 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Transferrin PF00405.15 001308518.1_02625001_1 - 4.3e-260 860.8 13.3 3e-171 568.8 0.2 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.5 001308518.1_02625001_1 - 1.4e-12 47.6 0.0 6.9e-06 25.7 0.0 2.6 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.18 001308518.1_02625001_1 - 0.19 11.0 0.1 11 5.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 Nop PF01798.16 001244674.2_39724001_3 - 2.1e-87 292.3 0.0 2.1e-87 292.3 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.11 001244674.2_39724001_3 - 1.2e-18 67.1 0.2 6.8e-18 64.6 0.2 2.5 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Cytochrom_NNT PF03264.12 001244674.2_39724001_3 - 1.1 8.8 3.3 2.1 7.9 3.3 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DUF1669 PF07894.10 001243845.2_39726001_1 - 8.6e-118 392.7 0.0 1.1e-117 392.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.4 001243845.2_39726001_1 - 3.2e-09 36.6 0.0 9.3e-09 35.1 0.1 1.7 2 0 0 2 2 2 1 PLD-like domain FXMRP1_C_core PF12235.6 001290248.1_22422001_1 - 2.8 8.4 6.4 4.9 7.7 6.4 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Ank_5 PF13857.4 001290248.1_22422001_2 - 6.3e-12 45.4 3.5 6e-05 23.2 0.6 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.4 001290248.1_22422001_2 - 1.2e-10 41.5 0.1 0.0098 16.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.5 001290248.1_22422001_2 - 2e-08 34.6 0.0 0.0037 17.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001290248.1_22422001_2 - 4.2e-06 26.8 0.3 0.019 15.3 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.4 001290248.1_22422001_2 - 0.0034 17.6 0.2 5.5 7.8 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Y_phosphatase PF00102.25 001308521.1_02628001_1 - 5.6e-158 523.4 2.8 7.4e-82 274.3 0.1 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CD45 PF12567.6 001308521.1_02628001_1 - 2.3e-24 85.0 6.8 2.3e-24 85.0 6.8 2.3 2 0 0 2 2 2 1 Leukocyte receptor CD45 fn3 PF00041.19 001308521.1_02628001_1 - 1.7e-16 60.2 5.0 4.8e-08 33.1 0.1 3.9 4 0 0 4 4 4 2 Fibronectin type III domain PTP_N PF12453.6 001308521.1_02628001_1 - 3.1e-16 58.6 2.9 8.1e-16 57.3 2.9 1.8 1 0 0 1 1 1 1 Protein tyrosine phosphatase N terminal Y_phosphatase3 PF13350.4 001308521.1_02628001_1 - 1.1e-07 31.9 0.0 0.0097 15.8 0.0 2.8 3 0 0 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.4 001308521.1_02628001_1 - 1.1e-05 25.5 0.0 0.49 10.4 0.0 3.7 3 0 0 3 3 3 2 Inositol hexakisphosphate DSPc PF00782.18 001308521.1_02628001_1 - 0.00068 19.3 0.0 0.074 12.7 0.0 3.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.11 001308521.1_02628001_1 - 0.0069 15.8 0.1 1.2 8.6 0.0 2.7 3 0 0 3 3 3 1 Tyrosine phosphatase family GnsAB_toxin PF08178.9 001308521.1_02628001_1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system MHC_II_alpha PF00993.18 001308528.1_02622001_2 - 4.4e-35 119.1 0.0 6.1e-35 118.6 0.0 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001308528.1_02622001_2 - 7.7e-27 92.3 0.8 7.7e-27 92.3 0.8 1.7 2 0 0 2 2 2 1 C1-set C-terminal domain C1-set PF07654.13 001308528.1_02622001_2 - 3.8e-25 88.0 0.0 5.9e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001308528.1_02622001_2 - 8e-05 23.0 0.0 0.00014 22.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001308528.1_02622001_2 - 8.7e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Marek_A PF02124.13 001308528.1_02622001_2 - 0.0029 17.4 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Marek's disease glycoprotein A ITAM PF02189.13 001308517.1_02622001_1 - 5e-20 70.5 10.6 3.1e-06 27.2 0.1 3.8 4 0 0 4 4 4 3 Immunoreceptor tyrosine-based activation motif TCR_zetazeta PF11628.6 001308517.1_02622001_1 - 5.7e-18 64.1 1.2 8.9e-18 63.5 1.2 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 zeta chain CD4-extracel PF09191.8 001308523.1_02623001_1 - 9e-45 151.4 2.8 3.7e-44 149.4 0.4 2.6 2 0 0 2 2 2 1 CD4, extracellular C2-set PF05790.13 001308523.1_02623001_1 - 7.3e-40 134.9 9.9 1.5e-19 69.8 0.4 3.7 3 0 0 3 3 3 2 Immunoglobulin C2-set domain ig PF00047.23 001308523.1_02623001_1 - 1.6e-22 79.3 5.6 1.8e-18 66.3 0.2 4.2 4 1 0 4 4 4 2 Immunoglobulin domain Tcell_CD4_C PF12104.6 001308523.1_02623001_1 - 2.1e-17 62.6 8.8 2.1e-17 62.6 8.8 1.8 2 0 0 2 2 1 1 T cell CD4 receptor C terminal region V-set PF07686.15 001308523.1_02623001_1 - 1.1e-13 51.1 0.1 1e-09 38.4 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.4 001308523.1_02623001_1 - 4.9e-11 42.9 3.3 1.5e-06 28.6 0.1 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.14 001308523.1_02623001_1 - 1.8e-10 40.6 1.7 8.9e-06 25.6 0.5 4.5 4 2 1 5 5 5 2 Immunoglobulin I-set domain Ig_2 PF13895.4 001308523.1_02623001_1 - 1.7e-09 37.8 1.2 0.00045 20.4 0.1 4.2 3 1 0 3 3 3 2 Immunoglobulin domain Receptor_2B4 PF11465.6 001308523.1_02623001_1 - 0.0026 17.8 0.3 0.019 15.0 0.1 2.5 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.3 001308523.1_02623001_1 - 0.029 14.3 0.0 12 5.9 0.0 3.1 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain ATP1G1_PLM_MAT8 PF02038.14 001308523.1_02623001_1 - 2 7.7 4.1 0.45 9.8 0.3 1.9 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family 7tm_1 PF00001.19 001308529.1_02623001_1 - 6.9e-52 176.2 16.2 1.5e-51 175.1 16.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CXCR4_N PF12109.6 001308529.1_02623001_1 - 2.6e-18 65.8 2.7 3.9e-18 65.2 2.7 1.3 1 0 0 1 1 1 1 CXCR4 Chemokine receptor N terminal 7TM_GPCR_Srsx PF10320.7 001308529.1_02623001_1 - 4.1e-06 26.2 15.3 5.7e-06 25.8 15.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4564 PF15169.4 001308529.1_02623001_1 - 0.16 11.5 0.3 0.31 10.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) TctB PF07331.9 001308529.1_02623001_1 - 3.1 7.9 10.7 0.43 10.7 2.1 2.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family COX2_TM PF02790.13 001308529.1_02623001_1 - 3.4 7.7 7.3 0.48 10.5 0.1 2.8 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain ODC_AZ PF02100.15 001289865.2_26723001_3 - 1e-20 73.7 0.0 2e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ald_Xan_dh_C2 PF02738.16 001282257.1_26729001_1 - 5.4e-187 622.4 0.1 7.2e-187 622.0 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001282257.1_26729001_1 - 2.1e-44 151.1 0.0 4.8e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001282257.1_26729001_1 - 1e-32 112.6 0.4 2.3e-32 111.5 0.4 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001282257.1_26729001_1 - 3.9e-30 103.5 1.0 1.1e-29 102.1 1.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001282257.1_26729001_1 - 1.8e-29 101.8 0.0 5.7e-29 100.2 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001282257.1_26729001_1 - 2.9e-09 36.6 3.4 7.7e-09 35.3 0.1 2.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain RhoGAP PF00620.25 001282257.1_26729001_1 - 0.076 12.7 0.3 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 RhoGAP domain TFIID-31kDa PF02291.13 001286240.1_26723001_2 - 9.6e-51 170.8 0.0 1.4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001286240.1_26723001_2 - 1.6e-07 31.7 0.2 3.2e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001286240.1_26723001_2 - 2.7e-06 27.6 0.1 5.4e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.11 001286240.1_26723001_2 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001286240.1_26723001_2 - 0.00022 21.5 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Histone PF00125.22 001286240.1_26723001_2 - 0.00034 20.9 0.3 0.00064 20.0 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 AAA_28 PF13521.4 001286240.1_26723001_2 - 0.00056 20.1 0.0 0.00083 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.4 001286240.1_26723001_2 - 0.00057 20.2 0.1 0.00057 20.2 0.1 1.8 2 0 0 2 2 1 1 AAA domain CENP-T_C PF15511.4 001286240.1_26723001_2 - 0.0041 17.1 0.1 0.0072 16.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001286240.1_26723001_2 - 0.008 16.4 0.1 0.015 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain SKI PF01202.20 001286240.1_26723001_2 - 0.019 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase RuvB_N PF05496.10 001286240.1_26723001_2 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.4 001286240.1_26723001_2 - 0.021 14.9 0.4 0.076 13.0 0.4 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.13 001286240.1_26723001_2 - 0.024 14.4 0.2 0.039 13.7 0.2 1.3 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.4 001286240.1_26723001_2 - 0.024 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.12 001286240.1_26723001_2 - 0.041 13.7 0.7 0.069 13.0 0.1 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.15 001286240.1_26723001_2 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.4 001286240.1_26723001_2 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.4 001286240.1_26723001_2 - 0.14 10.8 0.2 0.92 8.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.11 001286240.1_26723001_2 - 0.17 11.1 0.3 0.68 9.1 0.0 1.9 2 0 0 2 2 2 0 KaiC RXT2_N PF08595.9 001286240.1_26723001_2 - 0.2 11.5 2.0 0.32 10.9 2.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.10 001286240.1_26723001_2 - 1.4 8.4 7.7 2 7.9 7.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein 7tm_1 PF00001.19 001282263.1_26723001_3 - 7.7e-37 126.8 14.3 1.1e-36 126.3 14.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cytochrom_B_N_2 PF13631.4 001282263.1_26723001_3 - 0.00031 20.7 0.7 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB 7TM_GPCR_Srw PF10324.7 001282263.1_26723001_3 - 0.00031 20.0 8.2 0.0011 18.2 7.9 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srt PF10321.7 001282263.1_26723001_3 - 0.0023 16.8 20.3 0.23 10.2 20.4 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srv PF10323.7 001282263.1_26723001_3 - 0.0024 17.1 13.0 0.0058 15.9 12.0 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Sru PF10322.7 001282263.1_26723001_3 - 0.0071 15.6 0.4 0.0071 15.6 0.4 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Sru 7TM_GPCR_Srsx PF10320.7 001282263.1_26723001_3 - 0.019 14.2 10.0 0.54 9.4 0.5 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001282263.1_26723001_3 - 0.026 13.7 11.3 0.079 12.1 11.3 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001282263.1_26723001_3 - 0.079 12.5 9.2 1.2 8.7 9.2 2.1 1 1 0 1 1 1 0 Olfactory receptor Colipase PF01114.16 001282249.1_26722001_2 - 7.3e-27 92.6 4.0 1.7e-26 91.4 4.0 1.7 1 0 0 1 1 1 1 Colipase, N-terminal domain Colipase_C PF02740.12 001282249.1_26722001_2 - 7.3e-27 93.1 6.6 1.2e-26 92.5 6.6 1.3 1 0 0 1 1 1 1 Colipase, C-terminal domain Hormone_1 PF00103.18 001279978.1_46722001_1 - 5.3e-57 192.9 0.1 6e-57 192.7 0.1 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Peptidase_C1 PF00112.21 001280006.1_46723001_1 - 2.4e-82 276.2 5.4 3.4e-82 275.7 5.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001280006.1_46723001_1 - 4.6e-13 49.3 0.5 1.2e-12 47.9 0.5 1.8 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 001280006.1_46723001_1 - 0.00051 18.8 1.3 0.047 12.3 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family ATP-gua_Ptrans PF00217.17 001169031.1_40423001_1 - 9.8e-96 319.9 0.0 1.2e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.13 001169031.1_40423001_1 - 2e-31 108.1 0.0 3.2e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain VWA PF00092.26 001169027.1_40425001_1 - 1.3e-95 318.5 0.0 2.3e-49 167.9 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.4 001169027.1_40425001_1 - 1.8e-34 118.5 0.0 7.2e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain FXa_inhibition PF14670.4 001169027.1_40425001_1 - 3.4e-22 78.3 43.9 1.8e-09 37.6 7.7 3.6 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site cEGF PF12662.5 001169027.1_40425001_1 - 7.1e-13 48.1 16.9 4.8e-05 23.1 0.5 3.8 3 0 0 3 3 3 3 Complement Clr-like EGF-like Matrilin_ccoil PF10393.7 001169027.1_40425001_1 - 9.8e-12 44.4 0.4 1.8e-11 43.5 0.4 1.4 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin EGF_CA PF07645.13 001169027.1_40425001_1 - 2.5e-10 40.2 33.0 1.2e-06 28.5 5.0 3.5 3 0 0 3 3 3 3 Calcium-binding EGF domain EGF PF00008.25 001169027.1_40425001_1 - 1.4e-06 28.3 41.0 0.00052 20.1 6.8 4.0 4 0 0 4 4 4 3 EGF-like domain VWA_3 PF13768.4 001169027.1_40425001_1 - 1.7e-06 27.9 0.1 0.0015 18.3 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain DUF1194 PF06707.9 001169027.1_40425001_1 - 0.0059 15.7 0.0 0.48 9.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) hEGF PF12661.5 001169027.1_40425001_1 - 0.2 12.3 30.8 0.19 12.3 5.4 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF Interfer-bind PF09294.8 001168782.1_40422001_1 - 4.1e-31 107.2 0.1 1.2e-30 105.7 0.1 1.8 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001168782.1_40422001_1 - 1.2e-14 53.9 6.9 2.1e-14 53.1 0.0 2.9 2 1 0 2 2 2 1 Tissue factor fn3 PF00041.19 001168782.1_40422001_1 - 0.0067 16.6 3.0 0.038 14.2 0.8 2.9 2 2 0 2 2 2 1 Fibronectin type III domain DUF3844 PF12955.5 001168782.1_40422001_1 - 0.093 12.7 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) 53-BP1_Tudor PF09038.8 001168963.1_40429001_1 - 2.3e-77 256.7 0.3 4e-77 255.9 0.3 1.4 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor BRCT PF00533.24 001168963.1_40429001_1 - 0.00027 21.1 0.0 0.16 12.3 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.3 001168963.1_40429001_1 - 0.0058 16.9 0.1 0.073 13.4 0.1 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.3 001168963.1_40429001_1 - 0.0068 16.1 0.0 0.053 13.3 0.0 2.6 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain DUF4537 PF15057.4 001168963.1_40429001_1 - 0.025 14.4 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DZR PF12773.5 001168963.1_40429001_2 - 0.092 12.7 2.3 0.66 9.9 0.4 2.7 2 0 0 2 2 2 0 Double zinc ribbon MHC_II_alpha PF00993.18 001331060.1_40422001_1 - 6.9e-34 115.3 0.3 9.6e-34 114.8 0.3 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001331060.1_40422001_1 - 6.5e-29 99.0 0.3 1.2e-28 98.2 0.3 1.4 1 0 0 1 1 1 1 C1-set C-terminal domain C1-set PF07654.13 001331060.1_40422001_1 - 8e-24 83.8 0.0 1.3e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001331060.1_40422001_1 - 5.1e-05 23.7 0.0 8.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.13 001331060.1_40422001_1 - 0.0025 17.5 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Marek's disease glycoprotein A MITF_TFEB_C_3_N PF15951.3 001168746.1_40423001_1 - 5.8e-67 225.0 11.2 1.4e-66 223.7 11.2 1.7 1 0 0 1 1 1 1 MITF/TFEB/TFEC/TFE3 N-terminus DUF3371 PF11851.6 001168746.1_40423001_1 - 2.9e-35 121.9 6.3 2.9e-35 121.9 6.3 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3371) HLH PF00010.24 001168746.1_40423001_1 - 1.5e-15 56.7 0.7 3.3e-15 55.6 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VWA PF00092.26 001281594.1_31328001_3 - 5e-85 284.0 0.1 4.7e-28 98.5 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.16 001281594.1_31328001_3 - 5.1e-51 170.1 191.9 4.7e-09 35.7 26.1 7.3 1 1 5 6 6 6 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.4 001281594.1_31328001_3 - 7.5e-38 129.4 0.1 5.3e-16 59.1 0.0 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.4 001281594.1_31328001_3 - 3.4e-09 36.6 0.0 0.0011 18.7 0.1 3.5 3 1 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.12 001281594.1_31328001_3 - 8.1e-06 25.2 0.0 0.15 11.3 0.0 3.4 3 0 0 3 3 3 2 VWA domain containing CoxE-like protein Toprim_3 PF13362.4 001281594.1_31328001_3 - 0.1 12.8 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Toprim domain YcaO PF02624.14 001281594.1_31328001_3 - 0.17 11.0 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding ETF PF01012.19 001281594.1_31328001_3 - 0.18 11.5 0.1 0.34 10.6 0.1 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Ank_4 PF13637.4 001281385.1_31321001_1 - 2.8e-17 62.7 0.0 7.6e-07 29.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.4 001281385.1_31321001_1 - 2.3e-11 43.6 1.7 0.00021 21.4 0.3 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.5 001281385.1_31321001_1 - 1.4e-10 41.5 0.0 9.9e-07 29.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.4 001281385.1_31321001_1 - 2.3e-06 27.3 0.0 2.9 8.6 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.28 001281385.1_31321001_1 - 1.3e-05 25.3 0.1 0.059 13.7 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat DPPIV_N PF00930.19 001310571.1_31325001_1 - 1.1e-109 366.3 6.3 1.4e-109 366.0 6.3 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.19 001310571.1_31325001_1 - 1.8e-59 200.6 2.1 1.8e-59 200.6 2.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.16 001310571.1_31325001_1 - 2.5e-06 27.1 0.0 5.8e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.5 001310571.1_31325001_1 - 0.001 19.6 0.0 0.0047 17.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.12 001310571.1_31325001_1 - 0.001 18.3 0.1 0.0028 16.9 0.1 1.7 2 0 0 2 2 2 1 Secretory lipase Hydrolase_4 PF12146.6 001310571.1_31325001_1 - 0.0054 15.9 0.2 0.47 9.5 0.1 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.11 001310571.1_31325001_1 - 0.0075 16.0 0.2 0.11 12.2 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.14 001310571.1_31325001_1 - 0.0082 15.8 1.5 1.5 8.4 0.4 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.10 001310571.1_31325001_1 - 0.029 12.9 0.0 0.25 9.9 0.0 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.16 001310571.1_31325001_1 - 0.23 10.9 8.0 0.16 11.4 0.8 2.6 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Cys_knot PF00007.20 001281370.1_31322001_2 - 1.1e-31 109.0 3.0 1.4e-31 108.8 3.0 1.1 1 0 0 1 1 1 1 Cystine-knot domain DUF3772 PF12607.6 001281370.1_31322001_3 - 0.018 14.7 2.5 0.042 13.5 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) AA_permease_2 PF13520.4 001310565.1_31324001_1 - 3.7e-43 147.8 16.7 3.7e-43 147.8 16.7 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.19 001310565.1_31324001_1 - 8.5e-37 126.7 18.9 8.5e-37 126.7 18.9 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.4 001310565.1_31324001_1 - 3.5e-25 87.7 7.1 3.5e-25 87.7 7.1 3.1 4 0 0 4 4 4 1 C-terminus of AA_permease 7tm_1 PF00001.19 001319637.1_31323001_1 - 7.4e-34 117.1 20.8 1.1e-33 116.6 20.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4870 PF09685.8 001319637.1_31323001_1 - 0.018 15.0 3.1 0.018 15.0 3.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4870) SpoIIM PF01944.15 001319637.1_31323001_1 - 0.074 12.9 7.7 0.057 13.3 5.8 1.9 1 1 0 1 1 1 0 Stage II sporulation protein M DUF2678 PF10856.6 001319637.1_31323001_1 - 2.2 8.1 10.9 0.28 11.0 4.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Sec62 PF03839.14 001319637.1_31323001_1 - 4 6.8 5.6 0.51 9.7 0.9 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 Gastrin PF00918.15 001281707.1_31322001_3 - 6.3e-39 133.7 0.0 9.2e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Gastrin/cholecystokinin family RNase_H PF00075.22 001285915.1_31322001_1 - 5.2e-45 153.0 0.0 7e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285915.1_31322001_1 - 1.8e-18 66.4 0.5 3.3e-18 65.6 0.5 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285915.1_31322001_1 - 0.0018 17.8 0.0 0.005 16.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase-like Ank_4 PF13637.4 001281539.1_31322001_1 - 3.8e-11 43.2 0.0 0.00052 20.4 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.4 001281539.1_31322001_1 - 3.8e-10 39.7 0.6 0.00024 21.2 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001281539.1_31322001_1 - 1.4e-07 31.8 0.0 4.8e-07 30.2 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.28 001281539.1_31322001_1 - 6.9e-05 23.0 0.0 0.29 11.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.4 001281539.1_31322001_1 - 0.0018 18.5 0.0 0.75 10.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat IL8 PF00048.18 001281341.1_31322001_3 - 1.1e-13 51.0 0.8 1.6e-13 50.4 0.8 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like wnt PF00110.17 001281324.1_31323001_1 - 1.8e-106 356.0 15.2 2.1e-106 355.8 15.2 1.0 1 0 0 1 1 1 1 wnt family Pkinase PF00069.23 001281945.1_31325001_3 - 4.7e-54 183.4 0.2 1.1e-53 182.1 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001281945.1_31325001_3 - 3.8e-33 114.7 1.3 6.3e-33 114.0 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase dsrm PF00035.24 001281945.1_31325001_3 - 7.6e-26 90.5 8.9 1.2e-13 51.3 0.0 3.5 3 0 0 3 3 3 2 Double-stranded RNA binding motif Kdo PF06293.12 001281945.1_31325001_3 - 0.0045 16.2 0.0 0.0098 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DND1_DSRM PF14709.5 001281945.1_31325001_3 - 0.0051 16.9 3.1 0.13 12.4 0.0 3.1 2 1 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 Kinase-like PF14531.4 001281945.1_31325001_3 - 0.015 14.5 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.14 001281945.1_31325001_3 - 0.034 14.2 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC1 family MIF PF01187.16 001287197.1_52722001_2 - 2.2e-53 179.3 0.0 2.6e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Kelch_1 PF01344.23 001287197.1_52722001_2 - 0.09 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Kelch motif SNF2_N PF00176.21 001123183.1_49826001_3 - 4.2e-57 193.3 0.0 6.3e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.29 001123183.1_49826001_3 - 2.4e-15 56.7 0.0 4.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001123183.1_49826001_3 - 1.7e-08 34.5 0.0 2.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.6 001123183.1_49826001_3 - 4.2e-07 29.3 0.0 1.2e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.8 001123183.1_49826001_3 - 2.3e-06 27.8 0.1 2.6e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 Rad54 N terminal TLV_coat PF00429.17 001308485.1_02627001_2 - 2.7e-65 221.0 5.7 5.9e-62 210.0 2.2 2.3 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) CwsA PF10814.6 001308485.1_02627001_2 - 0.057 13.4 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA DUF3332 PF11810.6 029115.3_32924001_3 - 7 6.1 7.4 0.99 8.9 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) NAC PF01849.16 001282372.1_11322001_1 - 6.3e-25 86.8 0.8 1.4e-24 85.7 0.3 1.9 2 0 0 2 2 2 1 NAC domain CDK2AP PF09806.7 001281691.1_31322001_1 - 4.5e-20 72.6 0.0 6.2e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein 7tm_1 PF00001.19 001308336.1_10823001_1 - 1.1e-50 172.3 16.6 2.4e-50 171.2 16.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CXCR4_N PF12109.6 001308336.1_10823001_1 - 2.6e-18 65.8 2.7 3.9e-18 65.2 2.7 1.3 1 0 0 1 1 1 1 CXCR4 Chemokine receptor N terminal 7TM_GPCR_Srsx PF10320.7 001308336.1_10823001_1 - 5.8e-06 25.7 15.9 8e-06 25.3 15.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx COX2_TM PF02790.13 001308336.1_10823001_1 - 4.2 7.4 7.7 0.48 10.5 0.1 2.8 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain TctB PF07331.9 001308336.1_10823001_1 - 5.1 7.2 11.7 1.1 9.4 3.1 2.6 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family 7tm_1 PF00001.19 001287366.1_52123001_1 - 2.2e-51 174.5 16.6 4.9e-51 173.4 16.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CXCR4_N PF12109.6 001287366.1_52123001_1 - 2.8e-18 65.7 2.5 4.3e-18 65.1 2.5 1.3 1 0 0 1 1 1 1 CXCR4 Chemokine receptor N terminal 7TM_GPCR_Srsx PF10320.7 001287366.1_52123001_1 - 6.9e-06 25.5 15.4 9.5e-06 25.0 15.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx COX2_TM PF02790.13 001287366.1_52123001_1 - 3.8 7.6 7.5 0.48 10.5 0.1 2.8 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Orn_Arg_deC_N PF02784.14 001291698.1_09029001_2 - 2.5e-63 213.7 0.1 3.2e-63 213.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291698.1_09029001_2 - 8.6e-24 83.6 0.0 1.5e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain IIGP PF05049.11 001289890.1_24224001_1 - 8e-64 215.9 0.0 1e-63 215.6 0.0 1.0 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Asp_protease_2 PF13650.4 001302495.1_39629001_2 - 0.0008 19.9 0.0 0.0013 19.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001302495.1_39629001_2 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001302495.1_39629001_2 - 0.053 13.9 0.0 0.085 13.3 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001302495.1_39629001_3 - 5.3e-15 55.1 0.0 9.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001302495.1_39629001_3 - 1.3e-14 54.1 1.9 5e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001302495.1_39629001_3 - 0.001 19.0 1.1 0.0019 18.2 1.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001302495.1_39629001_3 - 0.002 17.9 4.7 0.0033 17.2 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001302495.1_39629001_3 - 0.0025 17.3 0.9 0.0064 16.0 0.2 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001302495.1_39629001_3 - 0.0069 16.1 0.4 0.011 15.4 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 CENP-H PF05837.10 001302495.1_39629001_3 - 0.23 11.7 4.8 0.47 10.8 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.10 001302495.1_39629001_3 - 0.32 11.3 9.2 0.68 10.3 9.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001302495.1_39629001_3 - 0.33 11.5 3.8 0.79 10.3 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF5082 PF16888.3 001302495.1_39629001_3 - 0.41 10.9 3.9 0.68 10.2 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CCDC106 PF15794.3 001302495.1_39629001_3 - 0.65 9.5 4.2 0.55 9.8 2.2 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SHE3 PF17078.3 001302495.1_39629001_3 - 0.79 9.3 7.3 1.6 8.3 7.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001302495.1_39629001_3 - 1.1 8.9 5.9 2.3 7.9 5.9 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001302495.1_39629001_3 - 1.5 8.8 8.4 3.3 7.8 8.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 001302495.1_39629001_3 - 1.7 8.3 5.3 3.3 7.3 5.3 1.4 1 0 0 1 1 1 0 IncA protein GIT_CC PF16559.3 001302495.1_39629001_3 - 2.1 8.3 7.1 5.2 7.0 7.1 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001302495.1_39629001_3 - 7.4 6.8 7.5 39 4.5 7.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family Orn_Arg_deC_N PF02784.14 001301740.1_52228001_1 - 1.5e-62 211.1 0.1 1.9e-62 210.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301740.1_52228001_1 - 4e-24 84.7 0.0 7.1e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291513.1_52228001_3 - 1.6e-62 211.1 0.1 2e-62 210.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291513.1_52228001_3 - 4.2e-24 84.6 0.0 7.4e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301730.1_39629001_1 - 1.5e-63 214.4 0.1 1.9e-63 214.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301730.1_39629001_1 - 3e-24 85.1 0.0 5.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Asp_protease_2 PF13650.4 001291091.1_24229001_2 - 0.00077 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291091.1_24229001_2 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291091.1_24229001_2 - 0.052 14.0 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291091.1_24229001_3 - 5.4e-15 55.1 0.0 9.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291091.1_24229001_3 - 1.3e-14 54.1 1.9 5e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001291091.1_24229001_3 - 0.00034 20.6 0.1 0.00065 19.7 0.1 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291091.1_24229001_3 - 0.002 17.9 4.7 0.0033 17.2 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291091.1_24229001_3 - 0.0028 17.2 0.2 0.0064 16.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291091.1_24229001_3 - 0.0068 16.1 0.4 0.011 15.5 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 CCDC106 PF15794.3 001291091.1_24229001_3 - 0.14 11.7 3.8 0.55 9.8 2.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001291091.1_24229001_3 - 0.24 11.7 4.8 0.47 10.8 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.10 001291091.1_24229001_3 - 0.32 11.3 9.2 0.68 10.3 9.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291091.1_24229001_3 - 0.34 11.4 3.8 0.79 10.2 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001291091.1_24229001_3 - 0.37 9.5 3.4 0.65 8.7 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.3 001291091.1_24229001_3 - 0.39 10.9 3.9 0.68 10.2 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) SHE3 PF17078.3 001291091.1_24229001_3 - 0.79 9.3 7.3 1.6 8.3 7.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001291091.1_24229001_3 - 1.2 8.8 5.9 2.3 7.9 5.9 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001291091.1_24229001_3 - 1.5 8.8 8.4 3.3 7.7 8.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 001291091.1_24229001_3 - 1.7 8.3 5.3 3.2 7.4 5.3 1.3 1 0 0 1 1 1 0 IncA protein GIT_CC PF16559.3 001291091.1_24229001_3 - 2.2 8.3 7.1 5.2 7.0 7.1 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291091.1_24229001_3 - 7 6.9 7.5 39 4.5 7.5 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family Asp_protease_2 PF13650.4 001291092.1_24229001_2 - 0.00077 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291092.1_24229001_2 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291092.1_24229001_2 - 0.052 14.0 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291092.1_24229001_3 - 5.4e-15 55.1 0.0 9.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291092.1_24229001_3 - 1.3e-14 54.1 1.9 5e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001291092.1_24229001_3 - 0.00034 20.6 0.1 0.00065 19.7 0.1 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291092.1_24229001_3 - 0.002 17.9 4.7 0.0033 17.2 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291092.1_24229001_3 - 0.0028 17.2 0.2 0.0064 16.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291092.1_24229001_3 - 0.0068 16.1 0.4 0.011 15.5 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 CCDC106 PF15794.3 001291092.1_24229001_3 - 0.14 11.7 3.8 0.55 9.8 2.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001291092.1_24229001_3 - 0.24 11.7 4.8 0.47 10.8 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.10 001291092.1_24229001_3 - 0.32 11.3 9.2 0.68 10.3 9.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291092.1_24229001_3 - 0.34 11.4 3.8 0.79 10.2 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001291092.1_24229001_3 - 0.37 9.5 3.4 0.65 8.7 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.3 001291092.1_24229001_3 - 0.39 10.9 3.9 0.68 10.2 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) SHE3 PF17078.3 001291092.1_24229001_3 - 0.79 9.3 7.3 1.6 8.3 7.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001291092.1_24229001_3 - 1.2 8.8 5.9 2.3 7.9 5.9 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001291092.1_24229001_3 - 1.5 8.8 8.4 3.3 7.7 8.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 001291092.1_24229001_3 - 1.7 8.3 5.3 3.2 7.4 5.3 1.3 1 0 0 1 1 1 0 IncA protein GIT_CC PF16559.3 001291092.1_24229001_3 - 2.2 8.3 7.1 5.2 7.0 7.1 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291092.1_24229001_3 - 7 6.9 7.5 39 4.5 7.5 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family Orn_Arg_deC_N PF02784.14 001293718.1_39625001_2 - 1.9e-69 233.7 0.0 2.3e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293718.1_39625001_2 - 1.5e-20 73.2 0.0 2.5e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293718.1_39625001_2 - 0.00015 21.2 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001291493.1_39629001_3 - 1.5e-63 214.4 0.1 2e-63 214.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291493.1_39629001_3 - 3e-24 85.1 0.0 5.5e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ODC_AZ PF02100.15 001290382.1_52222001_3 - 1.6e-15 57.0 0.0 2.4e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme WD40 PF00400.30 018255.3_26229001_1 - 7.6e-30 102.4 29.2 0.00015 22.4 1.8 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat DUF1725 PF08333.9 018255.3_26229001_3 - 6e-05 22.4 0.3 0.00014 21.2 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) p450 PF00067.20 001310560.1_31324001_2 - 9.8e-139 462.9 0.0 1.1e-138 462.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AI-2E_transport PF01594.14 121568.2_26224120_2 - 0.078 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 AI-2E family transporter TSNAXIP1_N PF15739.3 001353783.1_26229001_2 - 2e-13 50.6 0.1 3.2e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus Clathrin_H_link PF13838.4 001353783.1_26229001_3 - 6.4e-12 45.1 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Clathrin-H-link TSNAXIP1_N PF15739.3 001353783.1_26229001_3 - 0.0034 17.6 0.0 0.0034 17.6 0.0 2.3 3 0 0 3 3 3 1 Translin-associated factor X-interacting N-terminus SNURF PF07192.9 001349457.1_26225001_1 - 1.5e-42 143.1 3.9 2.6e-42 142.3 3.9 1.3 1 0 0 1 1 1 1 SNURF/RPN4 protein LSM PF01423.20 001349457.1_26225001_3 - 2e-19 68.9 0.1 2.8e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Asp PF00026.21 001303574.1_08523001_3 - 6.4e-118 393.6 0.3 7.4e-118 393.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001303574.1_08523001_3 - 3.5e-15 56.6 0.2 3.8e-10 40.2 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001303574.1_08523001_3 - 2e-12 46.5 0.6 3.6e-12 45.7 0.6 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.4 001303574.1_08523001_3 - 0.12 12.0 0.1 0.43 10.2 0.0 2.0 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Peptidase_M16 PF00675.18 001280125.1_39724001_1 - 4.5e-50 169.4 0.0 6.4e-50 168.9 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001280125.1_39724001_1 - 6.2e-32 110.9 0.0 1.3e-31 110.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain Ammonium_transp PF00909.19 001279570.1_24223001_1 - 2.1e-91 306.5 25.3 2.7e-91 306.1 25.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family AzlD PF05437.10 001279570.1_24223001_1 - 0.02 14.9 1.1 0.02 14.9 1.1 3.8 3 2 2 5 5 5 0 Branched-chain amino acid transport protein (AzlD) LMWPc PF01451.19 001290609.1_39922001_1 - 4.9e-51 172.7 0.0 5.8e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase TMEM206 PF15122.4 001290609.1_39922001_1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 TMEM206 protein family DUF4205 PF13898.4 001355536.1_32925001_2 - 1.6e-07 30.4 0.0 2.4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) DUF4205 PF13898.4 001355536.1_32925001_3 - 2.7e-40 138.2 0.0 1.2e-37 129.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) RVT_thumb PF06817.12 001165943.2_32929001_1 - 2e-14 52.9 1.0 4.1e-14 51.9 1.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain GP41 PF00517.15 001165943.2_32929001_1 - 7.4e-09 35.6 0.6 1.2e-08 34.9 0.6 1.2 1 0 0 1 1 1 1 Retroviral envelope protein RVT_1 PF00078.25 001165943.2_32929001_1 - 2.1e-06 27.3 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltr_RsmB-F PF01189.15 001165943.2_32929001_2 - 1.6e-44 151.8 0.0 2.9e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F rve PF00665.24 001165943.2_32929001_2 - 3.5e-24 85.2 0.0 6.9e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain GP41 PF00517.15 001165943.2_32929001_2 - 3e-17 63.0 2.1 5.2e-17 62.2 2.1 1.3 1 0 0 1 1 1 1 Retroviral envelope protein Integrase_Zn PF02022.17 001165943.2_32929001_2 - 1.8e-16 59.6 2.2 4.4e-16 58.4 2.2 1.7 1 0 0 1 1 1 1 Integrase Zinc binding domain Methyltransf_31 PF13847.4 001165943.2_32929001_2 - 1.2e-07 31.5 0.0 6.7e-07 29.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain FtsJ PF01728.17 001165943.2_32929001_2 - 1.4e-05 25.1 0.1 3.5e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase PUA PF01472.18 001165943.2_32929001_2 - 0.00024 20.9 0.3 0.00042 20.1 0.3 1.4 1 0 0 1 1 1 1 PUA domain RVT_1 PF00078.25 001165943.2_32929001_2 - 0.008 15.6 0.3 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PCMT PF01135.17 001165943.2_32929001_2 - 0.033 13.8 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DDE_Tnp_IS240 PF13610.4 001165943.2_32929001_2 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 DDE domain IN_DBD_C PF00552.19 001165943.2_32929001_3 - 1.1e-14 53.4 0.1 2.3e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 Integrase DNA binding domain RNase_H PF00075.22 001165943.2_32929001_3 - 5.5e-08 33.0 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 RNase H Actin PF00022.17 001330273.1_11723001_3 - 1.2e-151 504.8 0.0 3.9e-151 503.2 0.0 1.6 1 1 0 1 1 1 1 Actin SecE PF00584.18 001003325.1_08921001_2 - 1.8e-14 53.3 0.1 1.8e-14 53.3 0.1 1.6 2 0 0 2 2 2 1 SecE/Sec61-gamma subunits of protein translocation complex Zona_pellucida PF00100.21 001009330.2_22423001_1 - 3.6e-41 141.5 0.0 4.4e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Acyltransferase PF01553.19 212458.1_45725001_1 - 3.8e-33 113.8 0.0 5.3e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Branch PF02485.19 022276.1_45729001_1 - 5.5e-62 209.3 0.1 7.3e-62 208.9 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme SIP1 PF04938.10 001009183.1_26223001_2 - 2.9e-68 229.7 0.1 3.9e-68 229.3 0.1 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Proteasome PF00227.24 001004094.1_45722001_1 - 1.6e-51 174.4 0.1 2.5e-51 173.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001004094.1_45722001_1 - 3.5e-14 52.0 0.1 5.9e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Trypsin PF00089.24 022630.1_45723001_2 - 4.5e-67 225.9 1.7 5.6e-67 225.6 1.7 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 022630.1_45723001_2 - 2.3e-07 31.7 0.3 3.2e-07 31.2 0.3 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 022630.1_45723001_2 - 1.5e-06 28.4 0.1 2.5e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) zf-H2C2_2 PF13465.4 001014017.2_45725001_2 - 2.9e-71 232.8 71.5 4.7e-09 36.2 1.0 12.5 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.24 001014017.2_45725001_2 - 2.4e-54 178.7 80.9 3.6e-07 30.1 3.9 12.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001014017.2_45725001_2 - 4.2e-29 98.5 88.0 0.018 15.7 2.3 12.7 12 0 0 12 12 12 11 C2H2-type zinc finger KRAB PF01352.25 001014017.2_45725001_2 - 5.8e-22 77.0 0.6 1.1e-21 76.1 0.6 1.5 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001014017.2_45725001_2 - 2e-12 46.8 37.2 0.0011 18.9 2.1 7.7 4 1 5 9 9 9 6 Zinc ribbon domain zf-C2H2_jaz PF12171.6 001014017.2_45725001_2 - 2.4e-10 40.3 29.0 0.064 13.5 0.0 10.6 10 0 0 10 10 10 2 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.4 001014017.2_45725001_2 - 2.5e-08 33.5 31.9 1.2 9.0 0.1 10.8 10 0 0 10 10 10 2 Probable zinc-ribbon domain DUF3268 PF11672.6 001014017.2_45725001_2 - 1.6e-07 31.5 25.6 0.45 10.7 0.6 6.2 4 1 1 6 6 6 6 zinc-finger-containing domain zf-LYAR PF08790.9 001014017.2_45725001_2 - 1.1e-05 25.1 45.3 0.38 10.6 1.0 10.9 11 0 0 11 11 11 6 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.4 001014017.2_45725001_2 - 2.1e-05 24.2 66.2 0.042 13.7 1.5 11.8 12 0 0 12 12 11 5 C2H2-type zinc finger HypA PF01155.17 001014017.2_45725001_2 - 0.001 18.9 30.8 0.23 11.4 0.3 6.8 1 1 5 6 6 6 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.3 001014017.2_45725001_2 - 0.0041 17.7 41.0 0.66 10.6 0.5 7.4 1 1 5 8 8 7 4 zinc-ribbon family zf-C2HE PF16278.3 001014017.2_45725001_2 - 0.024 14.9 3.2 0.024 14.9 3.2 9.2 2 1 4 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger FYDLN_acid PF09538.8 001014017.2_45725001_2 - 0.039 14.5 20.0 16 6.1 0.1 8.3 1 1 7 8 8 8 0 Protein of unknown function (FYDLN_acid) zf-met PF12874.5 001014017.2_45725001_2 - 0.048 13.9 70.1 0.23 11.7 2.2 11.6 11 0 0 11 11 11 0 Zinc-finger of C2H2 type XPA_N PF01286.16 001014017.2_45725001_2 - 0.13 12.1 33.7 33 4.5 0.1 10.6 11 0 0 11 11 11 0 XPA protein N-terminal YhfH PF14149.4 001014017.2_45725001_2 - 2.6 8.0 33.4 21 5.1 0.1 10.0 10 0 0 10 10 10 0 YhfH-like protein ADK_lid PF05191.12 001014017.2_45725001_2 - 3.2 7.7 34.7 1 9.3 1.5 6.8 6 2 2 8 8 7 0 Adenylate kinase, active site lid zinc_ribbon_9 PF14369.4 001014017.2_45725001_2 - 3.3 7.9 33.7 10 6.4 0.1 9.1 9 1 0 9 9 9 0 zinc-ribbon zf-C2H2_11 PF16622.3 001014017.2_45725001_2 - 9.9 5.9 47.9 7 6.4 1.1 9.6 9 0 0 9 9 9 0 zinc-finger C2H2-type IQ PF00612.25 198026.2_32925001_3 - 0.001 18.6 0.3 0.0022 17.5 0.3 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Proteasome PF00227.24 001097476.2_49822001_3 - 9.3e-50 168.6 0.1 1.2e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.6 001097476.2_49822001_3 - 2.2e-15 55.6 1.0 5.2e-15 54.4 1.0 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Proteasome PF00227.24 001034040.2_06522001_2 - 2.8e-48 163.8 0.2 3.4e-48 163.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.6 001034040.2_06522001_2 - 4.6e-15 54.6 0.3 9.9e-15 53.5 0.3 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal zf-H2C2_2 PF13465.4 003456.2_26225001_3 - 9.3e-55 180.6 64.8 2.1e-08 34.1 1.6 9.6 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.24 003456.2_26225001_3 - 8.6e-42 139.2 75.9 2e-06 27.8 1.3 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 003456.2_26225001_3 - 3.1e-21 74.1 70.0 0.00025 21.5 1.5 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger KRAB PF01352.25 003456.2_26225001_3 - 2.9e-13 49.1 0.0 5.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 003456.2_26225001_3 - 4.5e-11 42.6 32.9 0.013 15.7 0.2 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 003456.2_26225001_3 - 3.9e-09 36.4 30.8 0.011 15.8 1.2 5.7 3 2 2 5 5 5 4 Zinc ribbon domain zf-C2H2_6 PF13912.4 003456.2_26225001_3 - 5.3e-07 29.3 52.2 0.015 15.1 0.3 8.6 8 0 0 8 8 8 4 C2H2-type zinc finger zf-met PF12874.5 003456.2_26225001_3 - 9.5e-05 22.5 58.5 0.0065 16.7 2.1 8.2 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-Di19 PF05605.10 003456.2_26225001_3 - 0.0013 18.8 40.1 0.0057 16.8 3.8 5.2 2 1 3 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.9 003456.2_26225001_3 - 0.14 12.0 28.4 0.28 11.0 0.9 6.9 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger C1_4 PF07975.10 003456.2_26225001_3 - 0.17 12.1 31.6 1 9.6 2.2 5.3 3 1 3 6 6 6 0 TFIIH C1-like domain zinc_ribbon_15 PF17032.3 003456.2_26225001_3 - 0.28 11.8 23.9 3.9 8.2 0.6 4.6 1 1 6 7 7 7 0 zinc-ribbon family DUF3268 PF11672.6 003456.2_26225001_3 - 3.2 8.0 22.9 0.96 9.7 0.9 4.4 1 1 2 5 5 5 0 zinc-finger-containing domain AKAP7_NLS PF10469.7 001007632.2_45724001_3 - 1.9e-59 200.9 0.6 2.5e-59 200.5 0.6 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.27 001007632.2_45724001_3 - 6e-08 32.3 0.6 1.1e-07 31.4 0.6 1.4 1 0 0 1 1 1 1 KH domain TraC_F_IV PF11130.6 001007632.2_45724001_3 - 0.025 14.0 0.0 0.29 10.6 0.0 2.3 3 0 0 3 3 3 0 F pilus assembly Type-IV secretion system for plasmid transfer Ig_3 PF13927.4 199082.2_45723001_3 - 0.0025 18.2 0.0 0.007 16.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain F-box-like PF12937.5 001106416.2_45726001_1 - 9.7e-14 50.9 3.9 2.2e-13 49.7 3.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001106416.2_45726001_1 - 4.6e-08 32.6 5.4 1.1e-07 31.4 5.4 1.7 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.31 001106416.2_45726001_1 - 1.9 9.2 13.9 44 5.0 0.1 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat V-set PF07686.15 001302663.1_46723001_1 - 2.6e-07 30.7 0.3 6.6e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001302663.1_46723001_1 - 5.2e-06 26.9 0.1 0.027 14.9 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 001302663.1_46723001_1 - 3.4e-05 24.0 0.2 0.018 15.2 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001302663.1_46723001_1 - 0.0008 19.4 0.4 1.5 8.9 0.3 3.1 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001302663.1_46723001_1 - 0.0062 16.4 0.0 0.087 12.8 0.0 2.5 3 0 0 3 3 3 1 Immunoglobulin I-set domain DUF4320 PF14208.4 001302663.1_46723001_1 - 0.057 13.4 0.2 5.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) Vpu PF00558.17 001302663.1_46723001_1 - 0.059 13.0 0.6 0.13 12.0 0.6 1.4 1 0 0 1 1 1 0 Vpu protein Flo11 PF10182.7 001302663.1_46723001_1 - 0.11 12.4 0.1 0.21 11.6 0.1 1.4 1 1 0 1 1 1 0 Flo11 domain Orn_Arg_deC_N PF02784.14 001291497.1_46729001_1 - 3.7e-64 216.4 0.2 4.9e-64 216.0 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291497.1_46729001_1 - 2.3e-24 85.5 0.0 4.3e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301731.1_46729001_2 - 3.5e-64 216.5 0.2 4.7e-64 216.1 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301731.1_46729001_2 - 2.2e-24 85.5 0.0 4.1e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Insulin PF00049.16 001280870.1_29222001_1 - 1.2e-12 48.5 7.8 3.5e-12 47.0 7.8 1.7 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001280870.1_29222001_1 - 0.0037 17.1 4.0 0.7 9.8 0.9 2.3 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type TSP_1 PF00090.17 001280870.1_29222001_3 - 9e-09 35.3 5.3 9e-09 35.3 5.3 1.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain Dickkopf_N PF04706.10 001280880.1_29224001_3 - 1.9e-16 60.1 16.8 1.9e-16 60.1 16.8 3.8 4 1 1 5 5 5 2 Dickkopf N-terminal cysteine-rich region ARD PF03079.12 001286027.1_29222001_1 - 1.2e-59 200.8 0.8 1.4e-59 200.6 0.8 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.9 001286027.1_29222001_1 - 2.2e-08 33.5 0.0 3.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.17 001286027.1_29222001_1 - 2.8e-05 23.9 0.0 4.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.20 001286027.1_29222001_1 - 0.03 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.4 001286027.1_29222001_1 - 0.051 13.2 0.0 0.36 10.5 0.0 1.9 1 1 0 1 1 1 0 Cupin-like domain Ribosomal_S7e PF01251.16 001286026.1_29222001_1 - 6.5e-94 312.7 3.8 7.3e-94 312.6 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ald_Xan_dh_C2 PF02738.16 001303260.1_29229001_1 - 2.6e-179 597.1 0.2 3.5e-179 596.7 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001303260.1_29229001_1 - 1.7e-40 138.4 0.0 3.5e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001303260.1_29229001_1 - 3.9e-30 104.3 2.4 1.1e-29 102.8 2.0 2.0 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001303260.1_29229001_1 - 5.1e-30 103.1 0.2 1.7e-29 101.5 0.2 2.0 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001303260.1_29229001_1 - 3.9e-29 100.7 0.0 1.8e-28 98.6 0.0 2.1 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001303260.1_29229001_1 - 2.8e-08 33.5 1.7 1.6e-07 31.0 0.0 2.9 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Perilipin PF03036.14 001113774.1_39523001_1 - 2.9e-124 415.0 7.3 2.4e-123 412.0 7.3 1.9 1 1 0 1 1 1 1 Perilipin family V-SNARE PF05008.13 001113774.1_39523001_1 - 0.01 16.1 0.1 2.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus ApoO PF09769.7 001113774.1_39523001_1 - 0.029 14.2 0.1 5.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Apolipoprotein O NPV_P10 PF05531.10 001113774.1_39523001_1 - 0.16 12.4 0.1 7.6 6.9 0.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Peptidase_S8 PF00082.20 001111122.1_39725001_1 - 4.5e-24 85.1 0.0 9.5e-24 84.0 0.0 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.14 001111122.1_39725001_1 - 3.1e-06 27.6 0.0 5.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1669 PF07894.10 001130565.1_45729001_3 - 1.5e-101 339.4 0.0 2.2e-101 338.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.4 001130565.1_45729001_3 - 2.4e-05 24.1 0.0 0.0001 22.1 0.0 1.9 2 0 0 2 2 2 1 PLD-like domain CTD PF12815.5 001130565.1_45729001_3 - 0.00067 20.0 18.7 0.0024 18.2 18.7 2.0 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Regulator_TrmB PF11495.6 001130565.1_45729001_3 - 0.21 10.6 0.1 0.34 9.9 0.1 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB DUF937 PF06078.9 001130565.1_45729001_3 - 0.25 11.8 1.4 0.5 10.8 0.5 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) GLTP PF08718.9 001114758.1_39722001_3 - 8.1e-44 149.4 0.0 1e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) EF-hand_1 PF00036.30 001195640.1_37923001_1 - 3.1e-41 135.7 9.6 1.8e-09 36.3 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001195640.1_37923001_1 - 2.5e-35 120.6 2.7 3.5e-18 65.7 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001195640.1_37923001_1 - 7.3e-33 112.0 9.4 6.5e-15 54.5 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001195640.1_37923001_1 - 4.6e-29 97.7 5.5 4.7e-09 35.3 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001195640.1_37923001_1 - 1.2e-25 87.7 6.9 3.7e-06 26.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001195640.1_37923001_1 - 2.7e-14 53.1 0.2 1.5e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001195640.1_37923001_1 - 8.1e-09 35.2 0.2 0.00035 20.4 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001195640.1_37923001_1 - 9.5e-07 29.0 0.0 0.025 14.8 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001195640.1_37923001_1 - 6.8e-05 23.6 0.0 0.007 17.1 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.8 001195640.1_37923001_1 - 0.00023 21.0 0.7 0.00052 19.9 0.1 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.11 001195640.1_37923001_1 - 0.00045 20.0 0.0 0.18 11.7 0.0 2.8 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) DUF1103 PF06513.9 001195640.1_37923001_1 - 0.0068 15.9 1.2 0.0091 15.5 1.2 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF4497 PF14924.4 001195640.1_37923001_1 - 0.012 16.0 0.0 5.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Caleosin PF05042.11 001195640.1_37923001_1 - 0.039 13.7 0.3 2.4 7.9 0.0 2.9 1 1 3 4 4 4 0 Caleosin related protein DUF3349 PF11829.6 001195640.1_37923001_1 - 0.041 14.5 0.3 7.2 7.3 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.14 001195640.1_37923001_1 - 0.054 13.7 0.2 6.8 6.9 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 TerB PF05099.11 001195640.1_37923001_1 - 0.067 13.0 0.4 4.1 7.2 0.0 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB GPHH PF16905.3 001195640.1_37923001_1 - 0.13 11.9 0.0 0.74 9.5 0.0 2.2 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated DUF2267 PF10025.7 001195640.1_37923001_1 - 0.17 12.1 0.0 0.41 10.8 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) SurA_N_2 PF13623.4 001195640.1_37923001_1 - 0.19 11.5 0.7 2.6 7.7 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain P53 PF00870.16 001172740.1_09925001_3 - 2.2e-112 373.2 1.1 3.1e-112 372.7 1.1 1.2 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.9 001172740.1_09925001_3 - 1.8e-16 59.0 2.0 4e-16 57.9 2.0 1.6 1 0 0 1 1 1 1 P53 tetramerisation motif P53_TAD PF08563.9 001172740.1_09925001_3 - 3.9e-13 48.3 3.2 9.9e-13 47.0 3.2 1.8 1 0 0 1 1 1 1 P53 transactivation motif Ribosom_S12_S23 PF00164.23 001282369.1_11322001_1 - 8.6e-64 213.1 2.0 1.2e-63 212.7 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 NDUF_B12 PF08122.10 001279717.1_24221001_1 - 2.1e-23 82.0 2.0 3.9e-23 81.1 2.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Ald_Xan_dh_C2 PF02738.16 001278764.1_09929001_1 - 2.5e-189 630.1 0.0 3.3e-189 629.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001278764.1_09929001_1 - 2.6e-42 144.3 0.1 5.7e-42 143.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001278764.1_09929001_1 - 1.7e-30 105.5 0.1 3e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001278764.1_09929001_1 - 5.7e-29 99.8 0.1 1.5e-28 98.4 0.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001278764.1_09929001_1 - 1.4e-28 99.0 0.0 3.6e-26 91.2 0.0 2.6 2 0 0 2 2 2 2 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001278764.1_09929001_1 - 8e-09 35.2 0.2 3.9e-08 33.0 0.2 2.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NDUF_B6 PF09782.7 001279763.1_24221001_1 - 1.9e-51 174.2 1.8 2.1e-51 174.0 1.8 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Sensor PF13796.4 001279763.1_24221001_1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Putative sensor PspB PF06667.10 001279763.1_24221001_1 - 1.3 9.0 4.2 0.66 9.9 1.3 1.9 2 0 0 2 2 2 0 Phage shock protein B zf-C2H2_7 PF15269.4 001279763.1_24221001_3 - 0.044 13.7 0.4 0.066 13.2 0.4 1.1 1 0 0 1 1 1 0 Zinc-finger Glyco_transf_29 PF00777.16 001244250.1_14225001_1 - 2.1e-75 253.4 0.0 2.7e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Lipocalin PF00061.21 001282265.1_26722001_2 - 2.2e-29 102.4 3.2 2.7e-29 102.1 3.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001282265.1_26722001_2 - 2.6e-10 40.2 0.9 3.5e-10 39.8 0.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_4 PF13648.4 001282265.1_26722001_2 - 0.015 16.1 1.2 0.021 15.6 1.2 1.2 1 0 0 1 1 1 0 Lipocalin-like domain DUF35_N PF12172.6 001282265.1_26722001_2 - 0.024 14.4 0.1 0.062 13.1 0.1 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) INTS2 PF14750.4 001100630.2_45729001_3 - 0 1587.1 21.0 0 1586.8 21.0 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 Med30 PF11315.6 001100630.2_45729001_3 - 0.04 14.0 0.1 0.75 9.9 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 30 TIR PF01582.18 001281307.1_16225001_1 - 1e-25 90.4 0.8 2e-25 89.5 0.8 1.5 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001281307.1_16225001_1 - 1.3e-21 76.0 34.0 1.1e-10 41.0 7.6 7.0 3 3 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.5 001281307.1_16225001_1 - 1.2e-17 63.5 39.1 6.1e-06 26.3 0.5 8.3 5 2 4 9 9 9 6 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001281307.1_16225001_1 - 2.3e-11 43.8 0.0 4.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001281307.1_16225001_1 - 2.8e-05 23.7 26.8 0.61 10.2 0.1 9.2 10 0 0 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.4 001281307.1_16225001_1 - 3.6e-05 23.2 13.1 0.053 12.9 1.0 4.3 2 2 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.31 001281307.1_16225001_1 - 8.7e-05 22.3 35.6 1.2 9.8 0.3 10.1 9 2 1 10 10 10 3 Leucine Rich Repeat LRRCT PF01463.22 001281307.1_16225001_1 - 0.0026 18.1 0.0 0.011 16.0 0.0 2.2 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain TIR-like PF10137.7 001281307.1_16225001_1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain AAA PF00004.27 001282260.1_26724001_1 - 1.3e-43 148.5 0.0 2.4e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 001282260.1_26724001_1 - 1.4e-06 28.7 0.2 0.00077 19.7 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.12 001282260.1_26724001_1 - 1.1e-05 25.3 0.1 0.0002 21.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.12 001282260.1_26724001_1 - 1.5e-05 25.1 0.0 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.4 001282260.1_26724001_1 - 1.9e-05 24.8 0.8 0.0035 17.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.10 001282260.1_26724001_1 - 3.8e-05 22.9 0.0 7.6e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Prot_ATP_ID_OB PF16450.3 001282260.1_26724001_1 - 0.00054 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Proteasomal ATPase OB/ID domain AAA_18 PF13238.4 001282260.1_26724001_1 - 0.00082 19.8 0.0 0.0032 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001282260.1_26724001_1 - 0.0022 18.0 0.0 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.11 001282260.1_26724001_1 - 0.0065 15.5 0.0 0.02 13.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.15 001282260.1_26724001_1 - 0.0092 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.9 001282260.1_26724001_1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.15 001282260.1_26724001_1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.4 001282260.1_26724001_1 - 0.012 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001282260.1_26724001_1 - 0.014 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.11 001282260.1_26724001_1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.19 001282260.1_26724001_1 - 0.018 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.15 001282260.1_26724001_1 - 0.022 14.3 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_11 PF13086.4 001282260.1_26724001_1 - 0.028 14.0 0.3 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.4 001282260.1_26724001_1 - 0.033 13.8 0.0 0.091 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.10 001282260.1_26724001_1 - 0.092 12.5 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.11 001282260.1_26724001_1 - 0.095 11.9 0.2 0.73 9.0 0.0 2.3 3 0 0 3 3 3 0 KaiC GAS PF13851.4 001282260.1_26724001_1 - 0.1 11.8 4.9 0.17 11.1 4.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_25 PF13481.4 001282260.1_26724001_1 - 0.1 12.0 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Med4 PF10018.7 001282260.1_26724001_1 - 0.27 10.8 2.9 0.53 9.8 2.9 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 AAA_23 PF13476.4 001282260.1_26724001_1 - 1.1 9.6 5.0 61 3.9 5.8 2.2 2 0 0 2 2 2 0 AAA domain IncA PF04156.12 001282260.1_26724001_1 - 2.2 7.9 5.8 4.4 6.9 5.8 1.4 1 0 0 1 1 1 0 IncA protein Rad51 PF08423.9 001246757.1_14223001_1 - 1e-129 431.1 0.1 1.2e-129 430.9 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.4 001246757.1_14223001_1 - 3.7e-10 39.6 0.0 5.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.19 001246757.1_14223001_1 - 2.8e-09 36.7 0.1 4.4e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.4 001246757.1_14223001_1 - 3.7e-08 33.7 1.0 1.2e-07 32.1 0.9 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.11 001246757.1_14223001_1 - 0.00014 21.1 1.8 0.00075 18.8 1.8 2.1 1 1 0 1 1 1 1 KaiC HhH-GPD PF00730.23 001246757.1_14223001_1 - 0.047 14.0 0.0 0.41 11.0 0.0 2.1 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.21 001246757.1_14223001_1 - 0.052 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DnaB_C PF03796.13 001246757.1_14223001_1 - 0.087 12.0 0.1 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain dNK PF01712.17 001279649.1_24223001_1 - 4e-34 118.2 0.0 5.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.15 001279649.1_24223001_1 - 0.0013 18.3 0.1 0.003 17.1 0.1 1.6 1 1 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.4 001279649.1_24223001_1 - 0.0035 17.6 0.2 1.1 9.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain Cytidylate_kin PF02224.16 001279649.1_24223001_1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_18 PF13238.4 001279649.1_24223001_1 - 0.045 14.1 0.0 0.26 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain SKI PF01202.20 001279649.1_24223001_1 - 0.089 12.8 0.3 1.2 9.1 0.1 2.5 3 0 0 3 3 3 0 Shikimate kinase DAD PF02109.14 001281624.1_31321001_3 - 1.4e-47 160.4 1.7 1.6e-47 160.2 1.7 1.0 1 0 0 1 1 1 1 DAD family TIR PF01582.18 001279189.1_39622001_1 - 4.4e-14 52.5 0.2 2e-13 50.4 0.2 2.0 1 1 0 1 1 1 1 TIR domain Death PF00531.20 001279189.1_39622001_1 - 4.7e-14 52.2 0.8 1.1e-13 51.0 0.1 2.0 3 0 0 3 3 3 1 Death domain TIR_2 PF13676.4 001279189.1_39622001_1 - 2.9e-12 46.7 0.0 5.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain UQ_con PF00179.24 001282268.1_26721001_1 - 1.8e-49 166.9 0.0 2e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001282268.1_26721001_1 - 3.7e-05 23.3 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Esterase PF00756.18 001270865.1_45723001_1 - 8.8e-70 235.1 0.0 1.1e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.5 001270865.1_45723001_1 - 0.00013 20.9 0.0 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.19 001270865.1_45723001_1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.7 001270865.1_45723001_1 - 0.00019 20.8 0.0 0.0017 17.7 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.10 001270865.1_45723001_1 - 0.00031 19.4 0.0 0.00044 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.6 001270865.1_45723001_1 - 0.0005 19.3 0.0 0.00072 18.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.14 001270865.1_45723001_1 - 0.0093 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.11 001270865.1_45723001_1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.23 001270865.1_45723001_1 - 0.037 13.8 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.9 001270865.1_45723001_1 - 0.13 11.1 0.0 0.41 9.5 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase Translin PF01997.14 001246675.1_14223001_1 - 1.9e-56 191.2 0.1 1.9e-56 191.2 0.1 1.5 2 0 0 2 2 2 1 Translin family NDUF_B5 PF09781.7 001279594.1_24222001_1 - 4.3e-88 293.7 0.0 4.8e-88 293.5 0.0 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DUF3749 PF12568.6 001279594.1_24222001_1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HSP70 PF00012.18 001246739.2_14225001_3 - 7.5e-272 902.8 9.3 8.6e-272 902.6 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001246739.2_14225001_3 - 8e-18 64.2 0.9 1.3e-16 60.2 0.3 2.4 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.4 001246739.2_14225001_3 - 9.6e-05 22.6 6.0 0.27 11.5 0.1 4.3 4 1 0 4 4 4 2 Cell division protein FtsA DUF4624 PF15417.4 001246739.2_14225001_3 - 0.0014 18.3 0.1 0.37 10.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4624) Hydantoinase_A PF01968.16 001246739.2_14225001_3 - 0.0041 16.3 1.9 0.017 14.2 0.1 2.7 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.8 001246739.2_14225001_3 - 0.012 14.4 1.1 0.028 13.3 0.5 1.8 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.14 001246739.2_14225001_3 - 0.047 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4795 PF16043.3 001246739.2_14225001_3 - 1 8.8 11.4 0.18 11.2 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Radial_spoke_3 PF06098.9 001246739.2_14225001_3 - 9.3 5.3 13.6 0.17 11.0 6.3 1.7 2 0 0 2 2 2 0 Radial spoke protein 3 Pyr_redox_2 PF07992.12 001246697.1_14224001_1 - 1.7e-66 224.3 4.7 1.7e-66 224.3 4.7 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.20 001246697.1_14224001_1 - 3.2e-42 143.1 0.4 8.1e-42 141.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.25 001246697.1_14224001_1 - 2.7e-18 66.2 5.0 7e-16 58.4 1.1 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.5 001246697.1_14224001_1 - 4.6e-09 36.0 0.0 4.6e-09 36.0 0.0 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.4 001246697.1_14224001_1 - 6.3e-09 35.4 2.0 2e-05 23.8 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001246697.1_14224001_1 - 4.5e-08 33.1 2.5 1.5e-05 25.0 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.22 001246697.1_14224001_1 - 6.1e-07 28.7 7.6 2.6e-06 26.7 0.3 2.8 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.20 001246697.1_14224001_1 - 8.3e-07 28.3 0.1 8.3e-07 28.3 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.19 001246697.1_14224001_1 - 1.6e-05 24.2 3.1 0.037 13.2 0.3 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.12 001246697.1_14224001_1 - 0.0002 20.1 9.9 0.00079 18.1 0.4 3.3 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.17 001246697.1_14224001_1 - 0.00023 20.4 4.4 0.015 14.5 0.1 3.2 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.4 001246697.1_14224001_1 - 0.00069 18.7 1.6 0.47 9.4 0.3 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.15 001246697.1_14224001_1 - 0.0011 18.1 0.4 0.0025 16.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.13 001246697.1_14224001_1 - 0.064 11.7 0.8 0.87 7.9 0.0 2.1 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Baseplate_J PF04865.12 001246697.1_14224001_1 - 0.067 12.2 1.1 1 8.3 0.2 2.4 2 0 0 2 2 2 0 Baseplate J-like protein UDPG_MGDP_dh_N PF03721.12 001246697.1_14224001_1 - 0.081 12.4 4.5 2.5 7.5 0.1 2.9 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.22 001246697.1_14224001_1 - 0.098 12.1 10.0 1.5 8.2 0.5 3.7 3 1 0 3 3 3 0 FAD dependent oxidoreductase 3HCDH_N PF02737.16 001246697.1_14224001_1 - 0.18 11.5 3.8 1.6 8.5 0.4 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Insulin PF00049.16 001282255.1_26721001_2 - 9e-25 87.4 1.3 1.1e-24 87.1 1.3 1.1 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001282255.1_26721001_2 - 0.088 12.7 5.4 0.67 9.9 0.2 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type NDUF_B8 PF05821.9 001279724.1_24222001_1 - 2.4e-77 258.7 6.5 2.7e-77 258.5 6.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Glucosamine_iso PF01182.18 001281599.1_31323001_3 - 4.7e-18 65.8 0.0 7.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase START PF01852.17 001281682.1_31324001_2 - 2.5e-53 180.4 0.0 3.6e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.18 001281682.1_31324001_2 - 0.045 13.8 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport CD4-extracel PF09191.8 001319342.1_10823001_1 - 7.2e-47 158.1 6.0 2e-46 156.7 1.1 3.4 4 0 0 4 4 4 1 CD4, extracellular C2-set PF05790.13 001319342.1_10823001_1 - 4.1e-38 129.3 7.0 2.5e-20 72.3 0.2 3.9 3 0 0 3 3 3 2 Immunoglobulin C2-set domain ig PF00047.23 001319342.1_10823001_1 - 5.9e-21 74.3 6.6 4e-16 58.8 0.3 4.2 4 1 0 4 4 4 2 Immunoglobulin domain Tcell_CD4_C PF12104.6 001319342.1_10823001_1 - 2.1e-17 62.6 8.8 2.1e-17 62.6 8.8 2.0 2 0 0 2 2 1 1 T cell CD4 receptor C terminal region Ig_3 PF13927.4 001319342.1_10823001_1 - 1.6e-12 47.7 4.6 1.2e-06 28.9 0.1 3.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.14 001319342.1_10823001_1 - 1.8e-11 43.8 3.6 1.2e-06 28.4 1.1 4.1 4 1 0 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.15 001319342.1_10823001_1 - 2.4e-11 43.6 1.2 7.6e-08 32.4 0.1 3.0 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.4 001319342.1_10823001_1 - 7.5e-09 35.7 5.3 0.0027 17.9 0.5 4.2 3 1 0 3 3 3 2 Immunoglobulin domain Receptor_2B4 PF11465.6 001319342.1_10823001_1 - 5.6e-05 23.2 0.6 0.00051 20.1 0.6 2.5 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.3 001319342.1_10823001_1 - 0.021 14.7 0.1 23 5.0 0.0 3.7 3 1 1 4 4 4 0 Izumo-like Immunoglobulin domain P_proprotein PF01483.18 001319342.1_10823001_1 - 0.035 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Proprotein convertase P-domain Pilin PF00114.17 001319342.1_10823001_1 - 0.039 14.7 0.3 0.9 10.3 0.0 2.6 2 0 0 2 2 2 0 Pilin (bacterial filament) Herpes_gE PF02480.14 001319342.1_10823001_1 - 0.048 12.3 0.0 0.54 8.8 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E ATP1G1_PLM_MAT8 PF02038.14 001319342.1_10823001_1 - 3.1 7.1 4.4 0.59 9.4 0.4 1.9 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family TNF PF00229.16 001305960.1_10822001_1 - 7.1e-34 116.4 2.6 1e-33 115.9 2.6 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family SSP160 PF06933.9 001305960.1_10822001_3 - 0.21 9.6 7.5 0.26 9.3 7.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.7 001305960.1_10822001_3 - 0.23 9.4 2.9 0.29 9.1 2.9 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ets PF00178.20 001191735.1_45725001_1 - 4.8e-34 116.5 1.5 8.7e-34 115.7 1.5 1.4 1 0 0 1 1 1 1 Ets-domain Elf-1_N PF12310.6 001191735.1_45725001_1 - 4.4e-30 104.3 0.1 1e-29 103.1 0.1 1.7 1 0 0 1 1 1 1 Transcription factor protein N terminal ERM PF00769.17 001009959.2_26228001_1 - 9.7e-05 22.2 0.4 9.7e-05 22.2 0.4 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family zf-TRAF PF02176.16 001305961.1_10824001_3 - 1.7e-20 73.3 36.0 2.4e-19 69.6 5.7 4.4 3 1 1 4 4 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.4 001305961.1_10824001_3 - 7.7e-10 38.3 5.8 7.7e-10 38.3 5.8 3.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001305961.1_10824001_3 - 1.8e-08 34.0 5.6 1.8e-08 34.0 5.6 3.7 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001305961.1_10824001_3 - 2.2e-07 30.5 4.7 2.2e-07 30.5 4.7 4.4 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001305961.1_10824001_3 - 2.6e-07 30.6 4.7 2.6e-07 30.6 4.7 3.8 3 1 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.4 001305961.1_10824001_3 - 7.1e-07 29.0 6.2 7.1e-07 29.0 6.2 2.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001305961.1_10824001_3 - 5e-06 26.4 4.2 5e-06 26.4 4.2 3.4 4 0 0 4 4 1 1 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.3 001305961.1_10824001_3 - 2.2e-05 24.7 7.6 2.2e-05 24.7 7.6 4.1 3 1 1 4 4 3 1 TRAF-like zinc-finger zf-RING_5 PF14634.4 001305961.1_10824001_3 - 4.1e-05 23.3 3.9 4.1e-05 23.3 3.9 4.2 3 1 1 4 4 2 1 zinc-RING finger domain SlyX PF04102.10 001305961.1_10824001_3 - 0.00039 20.9 2.9 0.00039 20.9 2.9 2.1 2 0 0 2 2 1 1 SlyX Spc29 PF17082.3 001305961.1_10824001_3 - 0.0023 17.7 1.1 0.004 16.9 1.1 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 U-box PF04564.13 001305961.1_10824001_3 - 0.0064 16.5 0.1 0.084 12.9 0.0 2.3 2 0 0 2 2 2 1 U-box domain Tropomyosin_1 PF12718.5 001305961.1_10824001_3 - 0.011 15.7 1.1 0.019 15.0 1.1 1.3 1 0 0 1 1 1 0 Tropomyosin like zf-RING_11 PF17123.3 001305961.1_10824001_3 - 0.014 15.0 3.6 0.067 12.8 3.6 2.3 1 0 0 1 1 1 0 RING-like zinc finger DUF16 PF01519.14 001305961.1_10824001_3 - 0.041 14.2 0.9 0.09 13.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 PspA_IM30 PF04012.10 001305961.1_10824001_3 - 0.044 13.2 1.9 0.079 12.4 1.9 1.4 1 0 0 1 1 1 0 PspA/IM30 family EzrA PF06160.10 001305961.1_10824001_3 - 0.052 11.6 0.7 0.073 11.1 0.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA KASH_CCD PF14662.4 001305961.1_10824001_3 - 0.052 13.2 2.2 0.081 12.6 2.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.6 001305961.1_10824001_3 - 0.074 13.0 2.2 0.14 12.1 2.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FliJ PF02050.14 001305961.1_10824001_3 - 0.087 12.9 6.5 0.16 12.0 6.5 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein Med21 PF11221.6 001305961.1_10824001_3 - 0.09 12.9 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex AAA_13 PF13166.4 001305961.1_10824001_3 - 0.093 11.3 0.3 0.13 10.8 0.3 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.6 001305961.1_10824001_3 - 0.097 11.8 0.5 0.16 11.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PI3K_P85_iSH2 PF16454.3 001305961.1_10824001_3 - 0.12 11.8 2.6 0.1 12.1 0.9 1.6 2 0 0 2 2 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Myosin_tail_1 PF01576.17 001305961.1_10824001_3 - 0.13 9.9 2.3 0.17 9.5 2.3 1.1 1 0 0 1 1 1 0 Myosin tail Tropomyosin PF00261.18 001305961.1_10824001_3 - 0.13 11.5 1.9 0.2 10.8 1.9 1.2 1 0 0 1 1 1 0 Tropomyosin HMMR_N PF15905.3 001305961.1_10824001_3 - 0.15 11.4 1.9 0.21 10.9 1.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.9 001305961.1_10824001_3 - 0.15 10.8 2.4 0.24 10.1 2.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.10 001305961.1_10824001_3 - 0.15 11.9 2.4 0.41 10.5 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.12 001305961.1_10824001_3 - 0.16 11.6 1.4 0.35 10.5 1.4 1.5 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.6 001305961.1_10824001_3 - 0.16 11.8 0.5 0.31 10.9 0.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.7 001305961.1_10824001_3 - 0.17 11.7 2.8 0.35 10.8 2.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.19 001305961.1_10824001_3 - 0.22 10.9 3.6 0.38 10.1 3.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.13 001305961.1_10824001_3 - 0.3 10.8 1.3 0.61 9.8 1.3 1.5 1 0 0 1 1 1 0 Septum formation initiator DM PF00751.16 001305961.1_10824001_3 - 0.3 10.9 14.9 0.67 9.8 0.7 3.4 2 1 1 3 3 3 0 DM DNA binding domain Sina PF03145.14 001305961.1_10824001_3 - 0.41 10.5 22.0 0.23 11.3 3.3 3.7 2 1 1 4 4 3 0 Seven in absentia protein family ABC_tran_CTD PF16326.3 001305961.1_10824001_3 - 0.48 10.6 2.0 3.1 8.0 2.1 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain PKcGMP_CC PF16808.3 001305961.1_10824001_3 - 2.8 7.7 4.8 3.1 7.6 0.2 2.8 2 1 2 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TIR PF01582.18 001305949.1_10822001_1 - 4.6e-14 52.5 0.2 2e-13 50.4 0.2 2.0 1 1 0 1 1 1 1 TIR domain Death PF00531.20 001305949.1_10822001_1 - 5e-14 52.1 0.8 1.1e-13 51.0 0.1 1.9 3 0 0 3 3 3 1 Death domain TIR_2 PF13676.4 001305949.1_10822001_1 - 3.1e-12 46.6 0.0 6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain Presenilin PF01080.15 001309945.1_31523001_1 - 5.5e-165 548.8 10.4 5.5e-165 548.8 10.4 1.5 2 0 0 2 2 2 1 Presenilin VIT1 PF01988.17 001309945.1_31523001_1 - 0.62 9.7 3.5 2 8.1 0.0 2.4 2 1 0 2 2 2 0 VIT family WD40 PF00400.30 001128212.2_26224001_2 - 7.2e-44 146.8 19.7 9.9e-07 29.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat U-box PF04564.13 001128212.2_26224001_2 - 2.7e-26 91.4 0.3 5.2e-26 90.5 0.3 1.5 1 0 0 1 1 1 1 U-box domain ANAPC4_WD40 PF12894.5 001128212.2_26224001_2 - 2.9e-14 53.0 0.0 0.0084 16.3 0.0 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SAM_2 PF07647.15 001128212.2_26224001_2 - 1.6e-11 44.0 0.3 3.1e-11 43.1 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001128212.2_26224001_2 - 4.8e-11 42.8 0.3 9.4e-11 41.9 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ge1_WD40 PF16529.3 001128212.2_26224001_2 - 5.9e-08 31.9 8.7 0.078 11.8 2.4 4.6 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.6 001128212.2_26224001_2 - 1.2e-07 30.3 0.1 0.005 15.1 0.1 2.4 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.9 001128212.2_26224001_2 - 2.7e-05 24.0 0.0 1.5 8.5 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A SAM_PNT PF02198.14 001128212.2_26224001_2 - 3.9e-05 23.4 0.1 9.1e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf-NOSIP PF15906.3 001128212.2_26224001_2 - 0.00054 19.9 0.0 0.00054 19.9 0.0 3.0 4 0 0 4 4 3 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.6 001128212.2_26224001_2 - 0.0077 15.9 0.5 0.018 14.7 0.0 1.8 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit PALB2_WD40 PF16756.3 001128212.2_26224001_2 - 0.0094 14.8 0.4 0.19 10.5 0.1 2.4 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain DUF2415 PF10313.7 001128212.2_26224001_2 - 2.8 7.8 4.9 27 4.7 0.1 4.2 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) Calponin PF00402.16 001310211.1_33423001_3 - 3.3e-43 144.8 21.2 1.3e-15 56.6 2.4 3.4 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.29 001310211.1_33423001_3 - 5e-24 84.5 0.1 7.7e-24 83.9 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.9 001310211.1_33423001_3 - 0.058 13.6 0.1 0.092 12.9 0.1 1.3 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.6 001310211.1_33423001_3 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain ALG3 PF05208.11 024535.1_45723120_3 - 1.5e-114 383.1 15.8 1.9e-114 382.7 15.8 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.4 024535.1_45723120_3 - 0.0012 18.1 15.7 0.0017 17.6 15.7 1.3 1 0 0 1 1 1 1 EpsG family WD40 PF00400.30 073140.1_45725120_1 - 0.0034 18.1 0.0 0.011 16.5 0.0 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat WD40 PF00400.30 073140.1_45725120_3 - 6.5e-16 58.3 5.1 1e-06 29.2 0.1 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 073140.1_45725120_3 - 7.8e-07 29.2 0.4 0.00076 19.6 0.2 3.3 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 073140.1_45725120_3 - 0.036 12.6 3.4 1.9 6.9 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 FtsX PF02687.19 073054.1_45728120_2 - 0.058 13.2 1.8 0.09 12.6 1.8 1.2 1 0 0 1 1 1 0 FtsX-like permease family P2X_receptor PF00864.17 073054.1_45728120_3 - 2.9e-146 487.1 1.4 3.5e-146 486.9 1.4 1.1 1 0 0 1 1 1 1 ATP P2X receptor Ribosomal_S4 PF00163.17 132728.1_45722120_3 - 1.1e-05 26.1 0.1 2e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.23 132728.1_45722120_3 - 1.2e-05 24.7 1.3 2.9e-05 23.5 1.3 1.7 1 0 0 1 1 1 1 S4 domain Glyco_transf_10 PF00852.17 199491.1_45725001_3 - 1.6e-57 194.0 0.0 2e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.3 199491.1_45725001_3 - 8.1e-36 122.7 0.0 1.4e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal SMN PF06003.10 172429.3_32925001_1 - 3.5e-15 55.8 1.4 3.5e-15 55.8 1.4 2.1 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.22 172429.3_32925001_1 - 0.0072 16.2 0.0 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 Tudor domain 7tm_1 PF00001.19 001309049.1_22424001_1 - 3.5e-50 170.6 30.2 5.8e-50 169.9 30.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.7 001309049.1_22424001_1 - 0.00017 20.9 19.8 0.00017 20.9 19.8 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MscS_TM PF12794.5 001309049.1_22424001_1 - 0.25 10.0 5.1 0.41 9.3 0.3 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Kinocilin PF15033.4 001357069.1_11726001_1 - 5.2e-72 239.3 0.2 7.1e-72 238.9 0.2 1.2 1 0 0 1 1 1 1 Kinocilin protein GBP_C PF02841.12 001102261.2_06526001_1 - 1.5e-118 395.4 21.0 2.1e-118 394.9 21.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain GBP PF02263.17 001102261.2_06526001_1 - 2e-117 391.0 0.1 2e-117 391.0 0.1 2.3 3 0 0 3 3 3 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.21 001102261.2_06526001_1 - 0.015 15.2 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MnmE_helical PF12631.5 001102261.2_06526001_1 - 0.022 14.8 0.5 0.059 13.4 0.5 1.6 1 1 0 1 1 1 0 MnmE helical domain MHC_I_3 PF16497.3 001046021.1_06523001_1 - 1.9e-73 246.0 0.0 2.4e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.13 001046021.1_06523001_1 - 6.6e-13 48.8 0.0 1.8e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001046021.1_06523001_1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_3 PF13927.4 001046021.1_06523001_1 - 0.02 15.4 0.1 0.44 11.1 0.0 2.3 1 1 1 2 2 2 0 Immunoglobulin domain DUF4381 PF14316.4 001046021.1_06523001_1 - 8.1 6.6 7.0 12 6.0 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) LRR_9 PF14580.4 001075904.1_06524001_2 - 5.9e-14 51.8 1.7 1.1e-13 50.9 1.7 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.5 001075904.1_06524001_2 - 9.2e-11 41.6 9.9 4.2e-05 23.7 2.3 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001075904.1_06524001_2 - 1.1e-05 24.9 5.4 1.1e-05 24.9 5.4 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.4 001075904.1_06524001_2 - 0.032 14.2 3.6 11 6.2 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Perilipin PF03036.14 001077046.1_06524001_2 - 5.9e-170 565.4 21.6 1.2e-169 564.4 21.6 1.5 1 1 0 1 1 1 1 Perilipin family DUF883 PF05957.11 001077046.1_06524001_2 - 0.23 12.0 15.2 3.2 8.2 0.7 4.7 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.10 001077046.1_06524001_2 - 0.36 10.7 7.4 2.2 8.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) KxDL PF10241.7 001077046.1_06524001_2 - 0.59 10.3 6.0 0.25 11.5 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein Aldedh PF00171.20 174239.2_06525001_1 - 6.2e-182 605.1 0.0 7.1e-182 604.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.12 174239.2_06525001_1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ion_trans PF00520.29 001024493.1_06526001_2 - 2.5e-15 56.2 17.4 3.3e-15 55.8 17.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.5 001024493.1_06526001_2 - 1.2e-14 54.6 0.1 5.1e-07 30.1 0.0 3.5 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001024493.1_06526001_2 - 1.3e-11 44.3 0.5 0.00051 20.2 0.1 4.0 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.28 001024493.1_06526001_2 - 3.5e-09 36.6 1.5 0.0012 19.0 0.1 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.4 001024493.1_06526001_2 - 2.9e-07 30.1 1.2 0.018 15.4 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.4 001024493.1_06526001_2 - 1e-06 29.0 0.0 0.021 15.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) 7tm_1 PF00001.19 001005261.1_08923001_1 - 3.6e-48 164.0 22.4 9.2e-48 162.7 22.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001005261.1_08923001_1 - 1.3e-07 31.2 20.2 1.6e-07 30.9 20.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.7 001005261.1_08923001_1 - 0.032 13.4 22.8 0.11 11.6 6.2 2.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Mito_carr PF00153.25 001075841.2_06524001_2 - 3.3e-49 164.7 0.1 8.1e-21 73.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TMPIT PF07851.11 001079600.1_06523001_2 - 7.5e-157 521.5 13.2 8.7e-157 521.3 13.2 1.0 1 0 0 1 1 1 1 TMPIT-like protein CEP209_CC5 PF16574.3 174722.2_06529001_3 - 7e-51 171.6 22.6 7e-51 171.6 22.6 12.8 5 3 9 16 16 16 1 Coiled-coil region of centrosome protein CE290 TBPIP PF07106.11 174722.2_06529001_3 - 0.005 16.5 8.2 0.005 16.5 8.2 15.9 3 3 13 17 17 17 6 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Transposase_1 PF01359.16 001103318.1_06526001_1 - 0.011 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Transposase (partial DDE domain) Transposase_1 PF01359.16 001103318.1_06526001_3 - 1.2e-12 47.3 0.1 2.8e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) 5-FTHF_cyc-lig PF01812.18 001075616.1_06524001_2 - 8.2e-58 195.2 0.0 1.1e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family XPG_N PF00752.15 001035113.1_06524001_3 - 1.2e-37 128.3 0.0 2.1e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.16 001035113.1_06524001_3 - 3.9e-30 103.9 0.0 7.2e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.18 001035113.1_06524001_3 - 7.7e-07 29.5 0.0 1.8e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.4 001035113.1_06524001_3 - 0.037 14.5 0.0 0.079 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Asp PF00026.21 176625.1_06523001_1 - 5.3e-101 338.0 0.0 6.2e-101 337.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 176625.1_06523001_1 - 3e-15 56.8 0.3 1.7e-08 34.8 0.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 176625.1_06523001_1 - 1.6e-14 53.3 1.4 2.9e-14 52.4 1.4 1.4 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.4 176625.1_06523001_1 - 8.9e-05 23.0 0.0 0.0035 17.9 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.4 176625.1_06523001_1 - 0.16 12.4 0.0 2.5 8.6 0.0 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Ion_trans PF00520.29 001003329.1_08924001_1 - 1e-50 172.1 10.9 1e-50 172.1 10.9 1.8 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.20 001003329.1_08924001_1 - 2e-25 88.8 0.0 3.9e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001003329.1_08924001_1 - 1.7e-14 53.4 4.1 1.7e-14 53.4 4.1 3.2 3 1 1 4 4 4 1 Ion channel PKD_channel PF08016.10 001003329.1_08924001_1 - 0.029 12.9 3.3 0.072 11.6 3.3 1.7 1 1 0 1 1 1 0 Polycystin cation channel Sigma_reg_N PF13800.4 001003329.1_08924001_1 - 0.12 12.5 0.4 11 6.3 0.0 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal SAA PF00277.16 001081853.1_21021001_1 - 8.5e-50 167.4 3.5 1e-49 167.1 3.5 1.1 1 0 0 1 1 1 1 Serum amyloid A protein MHC_I PF00129.16 001020810.1_08923001_1 - 5.1e-69 231.3 0.1 6.8e-69 230.9 0.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001020810.1_08923001_1 - 1.3e-15 57.5 0.0 3e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.10 001020810.1_08923001_1 - 0.00015 21.6 1.5 0.0091 15.9 0.1 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.4 001020810.1_08923001_1 - 0.00019 21.8 2.5 0.00093 19.6 0.1 2.9 2 1 1 3 3 3 1 Immunoglobulin domain MHC_I_C PF06623.9 001020810.1_08923001_1 - 0.00035 20.3 5.2 0.00086 19.1 5.2 1.7 1 1 0 1 1 1 1 MHC_I C-terminus Syndecan PF01034.18 001020810.1_08923001_1 - 0.036 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.4 001020810.1_08923001_1 - 0.092 13.4 0.0 0.31 11.8 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.12 001020810.1_08923001_1 - 4.9 6.8 5.4 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 IncA protein KRAB PF01352.25 001075261.1_06523001_3 - 2.8e-25 87.6 0.1 4.2e-25 87.0 0.1 1.3 1 0 0 1 1 1 1 KRAB box Mis12 PF05859.10 001076969.1_06524001_3 - 2.8e-28 98.5 0.8 5.1e-28 97.7 0.8 1.4 1 0 0 1 1 1 1 Mis12 protein 7tm_1 PF00001.19 001048107.1_08923001_1 - 1.1e-37 129.6 12.7 3e-37 128.2 12.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) T4_deiodinase PF00837.15 001007126.2_08923001_2 - 5.5e-116 385.8 0.1 7e-116 385.4 0.1 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase LSR PF05624.12 001083394.1_06524001_1 - 3.2e-23 81.3 37.7 5.5e-23 80.6 37.7 1.4 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.15 001083394.1_06524001_1 - 0.00011 22.2 0.2 0.0022 18.0 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.23 001083394.1_06524001_1 - 0.045 13.8 0.2 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.4 001083394.1_06524001_1 - 0.054 14.0 1.7 2.3 8.8 1.7 2.5 1 1 0 1 1 1 0 Immunoglobulin domain Pkinase PF00069.23 001075826.1_06523001_1 - 6.1e-33 114.2 0.3 8e-33 113.8 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001075826.1_06523001_1 - 4.9e-24 84.9 0.4 6.4e-24 84.5 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001075826.1_06523001_1 - 0.062 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001075826.1_06523001_1 - 0.086 12.6 0.0 0.59 9.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Collagen PF01391.16 001002980.1_08929001_1 - 1e-200 649.6 909.3 4e-09 36.0 24.1 29.8 2 2 22 24 24 24 21 Collagen triple helix repeat (20 copies) fn3 PF00041.19 001002980.1_08929001_1 - 5.9e-94 308.4 15.4 3.9e-15 55.8 0.2 9.3 9 0 0 9 9 9 9 Fibronectin type III domain VWA PF00092.26 001002980.1_08929001_1 - 6.5e-68 228.3 0.0 5.4e-44 150.4 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.4 001002980.1_08929001_1 - 3e-23 82.4 0.0 3.7e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Kunitz_BPTI PF00014.21 001002980.1_08929001_1 - 2.4e-17 62.8 1.7 3.9e-17 62.1 1.7 1.4 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Pur_ac_phosph_N PF16656.3 001002980.1_08929001_1 - 8.3e-14 51.8 10.2 0.051 14.0 0.7 9.2 8 4 0 8 8 8 3 Purple acid Phosphatase, N-terminal domain DUF4992 PF16383.3 001002980.1_08929001_1 - 3.9e-11 42.7 1.2 0.027 13.9 0.0 6.5 7 1 0 8 8 8 3 Domain of unknown function Interfer-bind PF09294.8 001002980.1_08929001_1 - 5.9e-06 26.4 0.0 1.2 9.3 0.0 5.7 6 1 1 7 7 7 1 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.7 001002980.1_08929001_1 - 0.11 12.9 0.0 55 4.2 0.0 4.1 4 1 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) Voltage_CLC PF00654.18 001003124.2_08929001_2 - 8e-84 281.7 30.4 8e-84 281.7 30.4 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.26 001003124.2_08929001_2 - 0.024 14.9 0.1 0.061 13.6 0.1 1.7 1 0 0 1 1 1 0 CBS domain CtaG_Cox11 PF04442.12 001083403.2_06523001_1 - 3.3e-62 208.8 0.3 4.4e-62 208.5 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 UCR_Fe-S_N PF10399.7 001083403.2_06523001_1 - 0.023 13.9 0.1 0.023 13.9 0.1 1.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fumarate_red_C PF02300.15 001083403.2_06523001_1 - 0.13 12.2 0.0 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 Fumarate reductase subunit C Collagen PF01391.16 001003187.1_08929001_3 - 1.3e-165 537.2 660.8 3.7e-09 36.1 34.8 20.9 2 1 15 17 17 17 14 Collagen triple helix repeat (20 copies) COLFI PF01410.16 001003187.1_08929001_3 - 1.7e-107 357.9 0.2 2.2e-107 357.6 0.2 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Pkinase PF00069.23 001048135.1_08924001_1 - 3e-56 190.6 0.0 5.7e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001048135.1_08924001_1 - 7e-33 113.9 0.0 1.5e-32 112.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase dsrm PF00035.24 001048135.1_08924001_1 - 2.2e-24 85.8 5.8 1.5e-13 51.1 0.1 3.4 3 0 0 3 3 3 2 Double-stranded RNA binding motif ABC1 PF03109.14 001048135.1_08924001_1 - 0.0035 17.4 0.0 0.0098 15.9 0.0 1.8 1 0 0 1 1 1 1 ABC1 family APH PF01636.21 001048135.1_08924001_1 - 0.013 15.3 0.0 0.32 10.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.4 001048135.1_08924001_1 - 0.02 14.4 0.2 0.28 10.7 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.12 001048135.1_08924001_1 - 0.039 13.2 0.0 0.084 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001048135.1_08924001_1 - 0.048 12.8 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Peptidase_S8_N PF16361.3 001048135.1_08924001_1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal of Subtilase family DND1_DSRM PF14709.5 001048135.1_08924001_1 - 0.31 11.2 1.9 0.72 10.0 0.1 2.5 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Interferon PF00143.17 001172041.1_06522001_1 - 1.2e-60 204.2 0.3 1.4e-60 204.0 0.3 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Longin PF13774.4 001309225.1_21024001_3 - 3.9e-19 68.3 0.2 6.6e-19 67.6 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1754 PF08555.8 001287072.1_08922001_2 - 1.5e-06 28.8 26.0 7e-06 26.6 20.8 2.3 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) UPF0172 PF03665.11 001287072.1_08922001_2 - 0.15 12.0 0.4 0.19 11.6 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) PRORP PF16953.3 001301261.1_21025001_1 - 1.6e-103 345.3 0.2 2.3e-103 344.8 0.2 1.2 1 0 0 1 1 1 1 Protein-only RNase P PPR_2 PF13041.4 001301261.1_21025001_1 - 0.022 14.8 0.0 8.2 6.6 0.0 3.4 2 1 1 3 3 3 0 PPR repeat family PPR PF01535.18 001301261.1_21025001_1 - 0.044 13.9 0.0 2.4 8.4 0.0 3.3 4 0 0 4 4 4 0 PPR repeat EB1 PF03271.15 001251946.1_08926001_2 - 1.5e-17 63.4 0.5 5.4e-17 61.6 0.4 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.29 001251946.1_08926001_2 - 6.7e-13 48.7 0.3 1.2e-12 47.9 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.6 001251946.1_08926001_2 - 0.025 14.3 0.1 0.084 12.6 0.0 1.9 2 0 0 2 2 2 0 CAMSAP CH domain zf-TRAF PF02176.16 001301218.1_21029001_3 - 6.1e-22 78.0 25.6 1.2e-14 54.6 9.6 4.7 3 1 1 4 4 3 2 TRAF-type zinc finger zf-C3HC4 PF00097.23 001301218.1_21029001_3 - 0.0024 17.5 13.6 0.0024 17.5 13.6 3.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) MPS2 PF17060.3 001301218.1_21029001_3 - 0.011 14.9 6.9 0.018 14.2 6.9 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Spc29 PF17082.3 001301218.1_21029001_3 - 0.044 13.5 4.3 0.08 12.6 4.3 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Spc7 PF08317.9 001301218.1_21029001_3 - 0.056 12.2 13.7 0.082 11.6 13.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FliJ PF02050.14 001301218.1_21029001_3 - 0.23 11.6 7.8 0.42 10.7 7.8 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein KxDL PF10241.7 001301218.1_21029001_3 - 0.23 11.6 3.4 0.43 10.7 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.5 001301218.1_21029001_3 - 0.28 11.2 13.3 0.65 10.0 13.3 1.6 1 1 0 1 1 1 0 Tropomyosin like T3SSipB PF16535.3 001301218.1_21029001_3 - 0.5 10.7 3.8 0.85 10.0 3.8 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB IncA PF04156.12 001301218.1_21029001_3 - 0.78 9.4 13.3 1.5 8.5 13.3 1.4 1 0 0 1 1 1 0 IncA protein ATG16 PF08614.9 001301218.1_21029001_3 - 1.4 8.9 16.1 0.24 11.4 8.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.10 001301218.1_21029001_3 - 2.1 8.2 5.2 1.9 8.4 3.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.7 001301218.1_21029001_3 - 3.3 8.0 7.4 1.7 8.9 3.6 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.6 001301218.1_21029001_3 - 3.9 6.6 8.1 5.9 6.0 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SPATA24 PF15175.4 001301218.1_21029001_3 - 4.2 7.1 12.4 2.2 8.0 9.3 1.8 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 ADIP PF11559.6 001301218.1_21029001_3 - 4.2 7.3 12.9 2.4 8.1 9.2 1.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Reprolysin_5 PF13688.4 001308552.1_21026001_1 - 5.7e-35 121.1 0.0 1.2e-34 120.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.4 001308552.1_21026001_1 - 1e-31 110.2 0.0 1.8e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.3 001308552.1_21026001_1 - 1.8e-21 76.1 16.9 1.8e-21 76.1 16.9 3.6 2 1 1 3 3 3 1 Membrane-proximal domain, switch, for ADAM17 Disintegrin PF00200.21 001308552.1_21026001_1 - 3.5e-15 56.4 23.9 3.5e-15 56.4 23.9 3.2 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.4 001308552.1_21026001_1 - 1.1e-12 48.4 0.0 2.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.17 001308552.1_21026001_1 - 1.2e-11 44.8 0.1 1.7e-06 27.9 0.1 3.2 3 0 0 3 3 3 2 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.17 001308552.1_21026001_1 - 7.3e-08 32.6 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.4 001308552.1_21026001_1 - 1.4e-05 24.7 0.1 2.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Filament PF00038.19 001346241.1_21026001_1 - 1e-112 376.7 25.6 1.2e-112 376.4 25.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.3 001346241.1_21026001_1 - 5.3e-33 114.3 102.1 3.1e-19 69.6 21.6 4.2 2 2 2 4 4 2 2 Keratin type II head CENP-F_leu_zip PF10473.7 001346241.1_21026001_1 - 2.1e-05 24.4 26.2 5.2e-05 23.2 8.8 3.3 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.10 001346241.1_21026001_1 - 6e-05 22.5 6.4 0.012 14.8 2.2 2.3 2 0 0 2 2 2 2 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.10 001346241.1_21026001_1 - 7.5e-05 22.7 32.0 0.00015 21.7 1.1 3.8 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein DUF4407 PF14362.4 001346241.1_21026001_1 - 0.00013 21.3 16.5 0.011 15.0 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) ADIP PF11559.6 001346241.1_21026001_1 - 0.00086 19.3 5.5 0.00086 19.3 5.5 3.9 3 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.9 001346241.1_21026001_1 - 0.0017 17.2 13.3 0.0017 17.2 13.3 3.5 1 1 3 4 4 4 1 Spc7 kinetochore protein Atg14 PF10186.7 001346241.1_21026001_1 - 0.0024 16.9 8.7 0.0024 16.9 8.7 2.2 1 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 TSNAXIP1_N PF15739.3 001346241.1_21026001_1 - 0.0061 16.8 1.8 0.0061 16.8 1.8 3.4 2 1 1 4 4 4 1 Translin-associated factor X-interacting N-terminus Alanine_zipper PF11839.6 001346241.1_21026001_1 - 0.013 15.7 4.8 0.013 15.7 4.8 2.1 3 0 0 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein Baculo_PEP_C PF04513.10 001346241.1_21026001_1 - 0.027 14.4 16.5 0.17 11.8 4.2 4.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.4 001346241.1_21026001_1 - 0.13 10.8 14.8 0.19 10.2 14.0 1.5 1 1 0 1 1 1 0 AAA domain MCC-bdg_PDZ PF10506.7 001346241.1_21026001_1 - 0.4 10.6 11.8 0.024 14.5 5.7 2.2 3 0 0 3 3 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DASH_Duo1 PF08651.8 001346241.1_21026001_1 - 0.68 9.6 6.5 4.8 6.9 1.3 3.4 3 0 0 3 3 3 0 DASH complex subunit Duo1 Jnk-SapK_ap_N PF09744.7 001346241.1_21026001_1 - 0.68 10.0 26.0 1.8 8.6 5.1 3.6 2 1 1 4 4 4 0 JNK_SAPK-associated protein-1 IncA PF04156.12 001346241.1_21026001_1 - 0.86 9.2 28.0 7.3 6.2 17.1 3.5 2 1 1 3 3 3 0 IncA protein Rootletin PF15035.4 001346241.1_21026001_1 - 1.4 8.8 18.4 0.36 10.7 5.6 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion SPATA1_C PF15743.3 001346241.1_21026001_1 - 3.1 7.7 16.2 0.27 11.2 0.4 3.0 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus Golgin_A5 PF09787.7 001346241.1_21026001_1 - 3.5 6.9 22.6 2.3 7.5 10.5 2.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 TMPIT PF07851.11 001346241.1_21026001_1 - 6.1 5.8 14.7 10 5.1 5.0 2.4 1 1 1 2 2 2 0 TMPIT-like protein TEX13 PF15186.4 001346241.1_21026001_1 - 8.4 5.9 9.5 2 7.9 4.9 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family ABC_tran_CTD PF16326.3 001346241.1_21026001_1 - 8.6 6.6 19.8 0.13 12.4 5.8 3.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain Syntaxin-6_N PF09177.9 001346241.1_21026001_1 - 9.4 6.7 11.7 1.7 9.1 3.3 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal RnaseA PF00074.18 001309410.1_21021001_1 - 7.6e-27 94.1 3.7 9.6e-27 93.8 3.7 1.0 1 0 0 1 1 1 1 Pancreatic ribonuclease Filament PF00038.19 001346172.1_21024001_2 - 2.5e-110 368.8 36.8 2.9e-110 368.6 36.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein Gp58 PF07902.9 001346172.1_21024001_2 - 0.0015 16.9 9.3 0.0015 16.9 9.3 1.5 1 1 1 2 2 2 1 gp58-like protein Lzipper-MIP1 PF14389.4 001346172.1_21024001_2 - 0.0095 16.0 4.4 0.0095 16.0 4.4 4.1 3 2 0 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 TPR_MLP1_2 PF07926.10 001346172.1_21024001_2 - 0.015 15.2 2.6 0.015 15.2 2.6 4.0 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.10 001346172.1_21024001_2 - 0.077 12.9 19.3 0.39 10.6 11.9 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4677 PF15726.3 001346172.1_21024001_2 - 0.091 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) TNF PF00229.16 001346172.1_21024001_2 - 0.2 11.5 2.2 1.6 8.5 0.1 2.8 3 0 0 3 3 3 0 TNF(Tumour Necrosis Factor) family Uso1_p115_C PF04871.11 001346172.1_21024001_2 - 0.39 10.9 20.4 0.78 10.0 5.5 2.9 2 2 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region NYD-SP28_assoc PF14775.4 001346172.1_21024001_2 - 0.76 9.8 10.6 3.4 7.7 1.0 3.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain Spc7 PF08317.9 001346172.1_21024001_2 - 1.8 7.2 30.7 1.1 7.9 10.6 2.4 1 1 0 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.7 001346172.1_21024001_2 - 2.3 8.3 34.0 1.4 9.0 9.8 3.7 1 1 2 4 4 4 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.10 001346172.1_21024001_2 - 3 7.7 18.0 2.9 7.8 2.0 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) FliD_C PF07195.10 001346172.1_21024001_2 - 3.3 6.9 9.2 2.5 7.4 5.7 2.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF5082 PF16888.3 001346172.1_21024001_2 - 6.1 7.1 21.1 5.8 7.2 8.8 3.9 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.8 001346172.1_21024001_2 - 7 6.7 25.4 4.1 7.4 9.6 3.5 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family ADIP PF11559.6 001346172.1_21024001_2 - 8.8 6.3 32.8 2.3 8.2 13.3 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding NAC PF01849.16 001252258.1_08922001_2 - 4.8e-25 87.2 1.0 1.4e-24 85.7 0.3 2.1 2 0 0 2 2 2 1 NAC domain RNA_pol_Rpo13 PF12136.6 001252258.1_08922001_2 - 0.05 13.4 3.9 0.15 11.8 3.9 1.8 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain Mem_trans PF03547.16 001252258.1_08922001_2 - 3.7 5.7 7.2 3.4 5.8 0.7 2.1 2 0 0 2 2 2 0 Membrane transport protein ECM1 PF05782.9 001252258.1_08922001_2 - 7.2 5.3 11.8 0.39 9.5 4.8 1.9 2 0 0 2 2 2 0 Extracellular matrix protein 1 (ECM1) DUF2203 PF09969.7 001252258.1_08922001_2 - 7.6 7.1 7.1 2.7 8.6 1.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ras PF00071.20 001301209.1_21027001_2 - 4.1e-54 182.4 0.0 5.6e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001301209.1_21027001_2 - 4.7e-19 68.7 0.0 6.9e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001301209.1_21027001_2 - 1.1e-07 31.3 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001301209.1_21027001_2 - 6.6e-05 22.7 0.5 0.049 13.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001301209.1_21027001_2 - 0.0012 18.3 0.0 0.0046 16.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001301209.1_21027001_2 - 0.0037 17.2 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase T2SSK PF03934.11 001301209.1_21027001_3 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K CRF PF00473.15 001014278.2_08924001_3 - 1.5e-15 56.8 1.1 1.5e-15 56.8 1.1 2.0 2 0 0 2 2 2 1 Corticotropin-releasing factor family IIGP PF05049.11 001313803.1_08925001_3 - 6.6e-149 495.9 0.1 8.3e-149 495.6 0.1 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.21 001313803.1_08925001_3 - 1.5e-06 28.1 0.0 3.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.25 001313803.1_08925001_3 - 0.00011 22.6 0.0 0.00026 21.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.21 001313803.1_08925001_3 - 0.00037 20.5 0.1 0.0059 16.5 0.2 2.2 1 1 1 2 2 2 1 Dynamin family Roc PF08477.11 001313803.1_08925001_3 - 0.00051 20.1 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF258 PF03193.14 001313803.1_08925001_3 - 0.006 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.4 001313803.1_08925001_3 - 0.0085 16.3 0.0 0.023 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.16 001313803.1_08925001_3 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.4 001313803.1_08925001_3 - 0.027 14.1 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.20 001313803.1_08925001_3 - 0.042 13.3 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Ras family AAA_21 PF13304.4 001313803.1_08925001_3 - 0.062 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.24 001313803.1_08925001_3 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.16 001313803.1_08925001_3 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Septin 7tm_4 PF13853.4 001017519.1_08923001_1 - 2.7e-49 168.3 24.3 3.3e-49 168.0 24.3 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001017519.1_08923001_1 - 1.5e-19 70.2 27.1 5.9e-19 68.2 27.1 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001017519.1_08923001_1 - 0.0014 17.9 29.3 0.0014 17.9 29.3 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Fungal_trans_2 PF11951.6 001017519.1_08923001_1 - 0.033 12.8 0.4 0.05 12.2 0.4 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF872 PF05915.10 001017519.1_08923001_1 - 8.6 6.5 8.7 2.3 8.3 0.7 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Defensin_beta_2 PF13841.4 001284451.1_08921001_1 - 7.4e-05 23.0 11.8 7.4e-05 23.0 11.8 1.8 2 0 0 2 2 2 1 Beta defensin Myticin-prepro PF10690.7 001284451.1_08921001_1 - 0.028 14.5 0.6 0.033 14.3 0.6 1.2 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Acyltransferase PF01553.19 001309262.1_21023001_3 - 9.7e-10 38.1 0.0 2e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.11 001309262.1_21023001_3 - 0.00026 19.9 0.0 0.00042 19.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Troponin PF00992.18 001003012.2_08923001_2 - 1.6e-35 122.2 51.3 2.5e-31 108.6 37.7 3.1 2 1 1 3 3 3 2 Troponin DARPP-32 PF05395.10 001313823.1_08922001_3 - 2e-37 128.7 7.3 2.6e-37 128.4 7.3 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 PLA2_B PF01735.16 001204236.1_08925001_1 - 1.4e-28 99.4 0.0 5.9e-28 97.4 0.0 1.8 2 0 0 2 2 2 1 Lysophospholipase catalytic domain C2 PF00168.28 001204236.1_08925001_1 - 1.2e-19 70.4 0.0 2.3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.4 001204236.1_08925001_1 - 0.072 12.5 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 CEP76 C2 domain SOCS_box PF07525.14 001003018.2_08923001_3 - 4.2e-09 36.5 1.3 1.1e-08 35.1 1.3 1.8 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.5 001003018.2_08923001_3 - 0.00035 21.0 0.0 0.0027 18.1 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001003018.2_08923001_3 - 0.001 19.5 0.0 0.0061 17.0 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.4 001003018.2_08923001_3 - 0.016 15.5 0.0 6.1 7.6 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat TPR_2 PF07719.15 001284469.1_08924001_1 - 9.8e-32 106.4 10.5 0.00073 19.3 0.3 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.26 001284469.1_08924001_1 - 1.7e-28 97.1 13.2 7.9e-05 22.2 0.4 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.4 001284469.1_08924001_1 - 9.1e-20 70.6 11.3 5.2e-06 26.5 1.4 6.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.4 001284469.1_08924001_1 - 2.9e-19 67.5 9.1 0.0032 17.4 0.1 6.4 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_14 PF13428.4 001284469.1_08924001_1 - 5.7e-19 67.1 10.5 0.019 15.6 0.0 8.3 5 2 4 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.4 001284469.1_08924001_1 - 3.1e-16 58.0 12.0 0.0066 16.3 0.1 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.4 001284469.1_08924001_1 - 2.6e-13 50.1 12.8 0.0031 17.9 0.0 6.3 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.4 001284469.1_08924001_1 - 2.4e-11 44.0 6.7 0.001 19.6 0.1 5.9 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.4 001284469.1_08924001_1 - 4e-11 42.4 8.5 0.0016 18.5 0.4 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.4 001284469.1_08924001_1 - 3.2e-09 36.7 11.6 0.65 10.6 0.4 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.4 001284469.1_08924001_1 - 2.4e-06 26.9 6.6 7.7e-06 25.2 0.7 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.4 001284469.1_08924001_1 - 7.3e-06 25.9 4.2 0.023 14.7 0.1 4.9 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.4 001284469.1_08924001_1 - 1.7e-05 24.3 11.3 3.2 7.4 0.1 5.7 3 1 2 5 5 5 2 TPR repeat ANAPC3 PF12895.5 001284469.1_08924001_1 - 3.6e-05 23.8 18.7 0.018 15.1 0.7 4.7 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.4 001284469.1_08924001_1 - 0.00053 19.6 12.0 0.077 12.8 0.8 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat Coatomer_E PF04733.12 001284469.1_08924001_1 - 0.00073 18.9 7.2 0.026 13.8 0.4 3.0 1 1 2 3 3 3 2 Coatomer epsilon subunit PknG_TPR PF16918.3 001284469.1_08924001_1 - 0.018 13.6 0.2 0.041 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat DUF5112 PF17139.2 001284469.1_08924001_1 - 0.023 14.1 0.4 0.023 14.1 0.4 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5112) NARP1 PF12569.6 001284469.1_08924001_1 - 0.028 13.2 5.8 1.1 8.0 0.0 3.2 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 PPR PF01535.18 001284469.1_08924001_1 - 0.16 12.2 1.8 21 5.5 0.2 4.7 6 0 0 6 6 5 0 PPR repeat TPR_4 PF07721.12 001284469.1_08924001_1 - 0.22 12.1 1.3 6.8 7.5 0.2 4.0 5 0 0 5 5 2 0 Tetratricopeptide repeat IIGP PF05049.11 001313846.1_08923001_1 - 2.3e-125 418.4 0.0 2.6e-125 418.2 0.0 1.0 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.21 001313846.1_08923001_1 - 2.1e-05 24.5 0.0 4.8e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.21 001313846.1_08923001_1 - 0.00056 19.9 0.0 0.29 11.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AAA_29 PF13555.4 001313846.1_08923001_1 - 0.054 13.1 0.3 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain PRK PF00485.16 001313846.1_08923001_1 - 0.13 11.9 0.2 0.35 10.5 0.1 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cu2_monoox_C PF03712.13 001081770.2_21028001_3 - 8e-65 217.0 0.0 1.3e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.18 001081770.2_21028001_3 - 4.3e-46 156.3 0.0 7.3e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.15 001081770.2_21028001_3 - 1.7e-26 92.7 0.0 2.9e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 DOMON domain UbiA PF01040.16 001145274.1_21023001_1 - 2.9e-57 193.7 14.8 4.1e-57 193.2 14.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Pkinase PF00069.23 001197157.1_08929001_3 - 1.2e-73 247.6 0.0 1.8e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.5 001197157.1_08929001_3 - 1.4e-51 172.9 4.8 6.3e-17 61.8 0.2 5.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001197157.1_08929001_3 - 4.1e-41 138.2 10.9 1.5e-08 34.6 0.0 7.8 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.4 001197157.1_08929001_3 - 5.2e-41 138.4 6.6 4e-09 36.7 0.0 7.2 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.28 001197157.1_08929001_3 - 1.3e-37 126.5 8.1 2.4e-06 27.6 0.0 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.4 001197157.1_08929001_3 - 2.7e-36 119.3 11.9 0.00011 22.2 0.0 9.5 9 0 0 9 9 8 7 Ankyrin repeat Pkinase_Tyr PF07714.15 001197157.1_08929001_3 - 5.3e-36 124.1 0.0 1e-35 123.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Death PF00531.20 001197157.1_08929001_3 - 4.6e-21 74.6 0.0 3.9e-20 71.7 0.0 2.7 3 0 0 3 3 3 1 Death domain COR PF16095.3 001197157.1_08929001_3 - 2.2e-06 27.5 0.0 6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Kdo PF06293.12 001197157.1_08929001_3 - 2.7e-06 26.8 0.0 5.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001197157.1_08929001_3 - 4.1e-05 23.1 0.1 7.9e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family AAA_23 PF13476.4 001197157.1_08929001_3 - 0.047 14.1 0.8 0.18 12.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain Roc PF08477.11 001197157.1_08929001_3 - 0.057 13.5 0.2 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Choline_kinase PF01633.18 001197157.1_08929001_3 - 0.071 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.21 001197157.1_08929001_3 - 0.09 12.5 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family AAA_29 PF13555.4 001197157.1_08929001_3 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.25 001197157.1_08929001_3 - 0.15 12.4 0.2 0.48 10.8 0.2 1.8 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.4 001197157.1_08929001_3 - 0.16 12.1 0.1 1.1 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.22 001257186.1_21025001_1 - 5.5e-22 77.9 0.1 2.3e-10 39.6 0.0 2.3 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family PIP49_C PF12260.6 001206721.1_06525001_2 - 4.3e-07 29.6 0.0 7.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase PF00069.23 001206721.1_06525001_2 - 0.004 16.4 0.0 0.0058 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001206721.1_06525001_2 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Stonin2_N PF12016.6 001191218.3_06526001_1 - 2.7e-174 579.3 27.0 5.2e-174 578.4 27.0 1.5 1 0 0 1 1 1 1 Stonin 2 Adap_comp_sub PF00928.19 001191218.3_06526001_1 - 2.3e-61 207.4 0.2 1.3e-60 204.9 0.0 1.9 2 0 0 2 2 2 1 Adaptor complexes medium subunit family SET PF00856.26 001349451.1_26229001_1 - 2.9e-05 24.4 2.8 3.7e-05 24.0 0.1 2.5 2 1 0 2 2 2 1 SET domain MIP PF00230.18 132651.1_08923120_2 - 7.6e-80 267.7 13.2 9e-80 267.5 13.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Defensin_beta_2 PF13841.4 132650.1_08922120_1 - 5.9e-09 36.1 12.9 1.2e-08 35.2 12.9 1.5 1 0 0 1 1 1 1 Beta defensin tRNA_Me_trans PF03054.14 028029.1_06523120_1 - 5.6e-60 202.9 0.0 7.2e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.12 028029.1_06523120_1 - 3.6e-06 26.6 0.0 4.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.15 028029.1_06523120_1 - 0.00077 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD synthase QueC PF06508.11 028029.1_06523120_1 - 0.056 12.8 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.14 028029.1_06523120_2 - 6.3e-69 232.3 0.0 8e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase Neugrin PF06413.9 028054.1_06524120_3 - 2.3e-95 318.8 0.0 3e-95 318.4 0.0 1.1 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.5 028054.1_06524120_3 - 0.0037 17.3 0.1 0.006 16.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SelK_SelG PF10961.6 144938.1_06522120_3 - 1.7e-08 34.8 1.3 2.8e-08 34.1 1.3 1.3 1 0 0 1 1 1 1 Selenoprotein SelK_SelG GSHPx PF00255.17 138142.1_06523120_2 - 6.3e-27 93.2 0.2 9.5e-27 92.6 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Rdx PF10262.7 146805.1_06527120_1 - 1.3e-09 38.0 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Rdx family DUF3791 PF12668.5 103807.1_06525120_1 - 0.026 14.4 0.1 0.087 12.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Helicase_C PF00271.29 103807.1_06525120_2 - 2.9e-30 104.8 0.1 5.3e-30 103.9 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.27 103807.1_06525120_2 - 2.3e-12 46.9 0.0 5.5e-12 45.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD PF00270.27 103807.1_06525120_3 - 3.4e-20 72.4 0.0 5.5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.13 103807.1_06525120_3 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Endonuc-EcoRV PF09233.9 045536.1_06523120_2 - 0.0063 15.8 0.2 0.009 15.3 0.2 1.1 1 0 0 1 1 1 1 Restriction endonuclease EcoRV 7tm_4 PF13853.4 003184.1_08921120_2 - 4.8e-19 69.0 3.9 5.7e-19 68.8 3.9 1.0 1 0 0 1 1 1 1 Olfactory receptor Romo1 PF10247.7 003184.1_08921120_2 - 0.29 11.4 7.3 0.11 12.7 3.6 2.1 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 PPARgamma_N PF12577.6 003097.1_06527120_1 - 1.4e-31 108.9 1.4 3.2e-31 107.7 1.4 1.7 1 0 0 1 1 1 1 PPAR gamma N-terminal region zf-C4 PF00105.16 003097.1_06527120_1 - 4.2e-27 94.3 15.0 7.2e-27 93.5 15.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) tRNA_int_endo PF01974.15 003097.1_06527120_1 - 4.7e-20 71.3 0.0 2.3e-19 69.1 0.0 2.1 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.12 003097.1_06527120_1 - 5.6e-17 61.0 0.3 1.5e-12 46.8 0.1 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Hormone_recep PF00104.28 003097.1_06527120_1 - 8.1e-08 32.0 0.0 2.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Tmemb_55A PF09788.7 003097.1_06527120_1 - 0.057 12.4 3.2 0.094 11.6 3.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A Pro_isomerase PF00160.19 036671.1_08922120_1 - 8.7e-38 129.9 0.4 1.1e-37 129.6 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.19 036669.1_08922120_2 - 2e-08 34.5 0.0 3.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.19 036669.1_08922120_3 - 8.4e-30 104.0 0.2 1.1e-29 103.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FixQ PF05545.9 038187.1_06521120_3 - 0.082 12.7 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ NEP PF10167.7 027315.1_06524120_1 - 1.2e-39 134.6 0.1 1.2e-39 134.6 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein SRF-TF PF00319.16 027315.1_06524120_1 - 2.4e-23 81.2 0.3 4.9e-23 80.2 0.3 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SR-25 PF10500.7 027315.1_06524120_1 - 0.0038 16.7 18.3 0.0056 16.2 18.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4604 PF15377.4 027315.1_06524120_2 - 0.056 13.8 13.8 0.08 13.2 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) AP3D1 PF06375.9 027315.1_06524120_2 - 1.4 9.0 19.0 2 8.6 19.0 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4604 PF15377.4 027315.1_06524120_3 - 0.012 15.9 10.9 0.022 15.1 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) ig PF00047.23 036568.1_21023120_2 - 3.8e-11 42.9 0.1 0.00018 21.5 0.3 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 036568.1_21023120_2 - 4.3e-05 23.7 0.0 0.037 14.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 036568.1_21023120_2 - 0.00011 22.6 0.1 0.051 14.1 0.1 3.1 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 036568.1_21023120_2 - 0.00063 19.7 0.1 14 5.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin V-set domain DUF4721 PF15848.3 036568.1_21023120_3 - 1.3 9.4 7.6 6.2 7.2 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4721) Pro_isomerase PF00160.19 036670.1_08922120_3 - 1.5e-46 158.5 0.2 1.7e-46 158.2 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.19 036673.1_08922120_1 - 6e-16 59.0 0.0 8.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.19 036673.1_08922120_2 - 5.5e-23 81.8 0.1 6.4e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MHC_I PF00129.16 036560.1_21023120_1 - 2e-18 66.4 0.0 2.8e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 036560.1_21023120_3 - 1e-11 45.0 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 036560.1_21023120_3 - 9.5e-11 41.4 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 BiPBP_C PF06832.10 036560.1_21023120_3 - 0.019 14.8 0.0 0.071 13.0 0.0 1.9 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Ig_2 PF13895.4 036566.2_21023120_1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain DUF4721 PF15848.3 036566.2_21023120_1 - 0.048 14.0 2.3 6.9 7.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4721) ig PF00047.23 036566.2_21023120_3 - 2.3e-13 50.0 0.0 3.4e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 036566.2_21023120_3 - 3.2e-07 30.7 0.0 0.00025 21.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 036566.2_21023120_3 - 3.7e-06 27.0 0.0 0.021 15.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 036566.2_21023120_3 - 0.00014 21.8 1.3 4.6 7.3 0.0 3.2 2 1 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.23 036567.1_21022120_2 - 3.7e-05 23.7 0.3 0.00012 22.1 0.3 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 036567.1_21022120_2 - 0.0037 17.7 0.2 0.036 14.6 0.2 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 036567.1_21022120_2 - 0.0095 16.1 0.1 0.024 14.9 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 036567.1_21022120_2 - 0.066 13.2 0.6 10 6.2 0.0 2.6 3 0 0 3 3 3 0 Immunoglobulin V-set domain Pro_isomerase PF00160.19 036672.1_08922120_2 - 6.2e-35 120.7 0.2 7.7e-35 120.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SAA PF00277.16 001357495.1_29722001_1 - 2.1e-39 134.0 0.2 3e-39 133.5 0.2 1.2 1 0 0 1 1 1 1 Serum amyloid A protein DUF1049 PF06305.9 132745.2_39722120_3 - 0.0023 17.6 0.5 0.004 16.8 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) IL8 PF00048.18 001009827.1_22422001_1 - 1.7e-19 69.6 1.1 3e-19 68.8 1.1 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like p450 PF00067.20 001048013.1_22424001_1 - 1.9e-101 340.0 0.0 2.3e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ets PF00178.20 001001865.1_49823001_2 - 1.2e-22 80.1 2.4 1.9e-22 79.4 2.4 1.4 1 0 0 1 1 1 1 Ets-domain 7tm_2 PF00002.22 001009727.1_39523001_1 - 2.3e-78 262.8 18.9 3.1e-78 262.3 18.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.20 001009727.1_39523001_1 - 1.4e-12 47.6 1.1 2.9e-12 46.5 1.1 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF2976 PF11190.6 001009727.1_39523001_1 - 0.17 11.5 1.0 24 4.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Tissue_fac PF01108.15 001009748.1_39529001_2 - 1.7e-26 92.0 3.1 2.4e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 Tissue factor Interfer-bind PF09294.8 001009748.1_39529001_2 - 3.8e-22 78.4 0.1 7.5e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III PPV_E1_C PF00519.15 001009748.1_39529001_2 - 0.06 12.0 0.4 0.095 11.4 0.4 1.1 1 0 0 1 1 1 0 Papillomavirus helicase WAP PF00095.19 001035225.1_39521001_1 - 4.5e-19 68.4 37.0 9.4e-10 38.6 10.9 2.1 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Phosducin PF02114.14 001043340.1_22422001_1 - 9.3e-133 441.0 2.0 1.1e-132 440.8 2.0 1.0 1 0 0 1 1 1 1 Phosducin COesterase PF00135.26 001082765.2_37924001_2 - 8.3e-164 546.1 0.0 9.5e-164 546.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001082765.2_37924001_2 - 7.4e-11 42.2 1.3 4.3e-10 39.7 1.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001082765.2_37924001_2 - 0.00027 20.3 0.0 0.00056 19.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.7 001082765.2_37924001_2 - 0.024 13.4 0.0 0.088 11.5 0.0 1.8 1 1 0 1 1 1 0 Steryl acetyl hydrolase Esterase PF00756.18 001082765.2_37924001_2 - 0.026 14.0 0.3 0.1 12.1 0.3 1.8 1 1 0 1 1 1 0 Putative esterase P53 PF00870.16 001082404.1_37925001_1 - 1.6e-114 380.2 1.3 2.4e-114 379.7 1.3 1.2 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.9 001082404.1_37925001_1 - 1.2e-16 59.6 3.9 2.2e-16 58.7 3.9 1.4 1 0 0 1 1 1 1 P53 tetramerisation motif P53_TAD PF08563.9 001082404.1_37925001_1 - 1.8e-12 46.2 7.0 3.6e-12 45.2 7.0 1.6 1 0 0 1 1 1 1 P53 transactivation motif DEC-1_N PF04625.11 001082404.1_37925001_1 - 1 8.2 3.7 1.5 7.6 3.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Collagen PF01391.16 001082404.1_37925001_3 - 0.92 9.2 11.4 2.2 8.0 5.6 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) GSHPx PF00255.17 001077512.2_39722001_2 - 1.7e-37 127.1 0.0 2.2e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Caveolin PF01146.15 001168694.1_22427001_3 - 9.3e-55 184.1 0.8 1.5e-54 183.4 0.8 1.3 1 0 0 1 1 1 1 Caveolin Filament PF00038.19 001098563.1_39724001_2 - 1.8e-98 329.9 16.1 2.4e-98 329.4 16.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein Phage_Mu_Gam PF07352.10 001098563.1_39724001_2 - 0.0097 15.7 15.5 0.013 15.2 0.3 3.7 3 1 0 4 4 4 2 Bacteriophage Mu Gam like protein TPR_MLP1_2 PF07926.10 001098563.1_39724001_2 - 0.21 11.5 32.8 0.038 13.9 1.4 3.8 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.10 001098563.1_39724001_2 - 1.5 8.1 8.8 0.28 10.4 2.9 2.3 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Allexi_40kDa PF05549.9 001098563.1_39724001_2 - 2 7.7 6.8 0.37 10.1 2.4 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Atg14 PF10186.7 001098563.1_39724001_2 - 2 7.3 10.2 1.2 8.0 4.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.12 001098563.1_39724001_2 - 2.5 7.8 8.5 1.4 8.5 4.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.17 001098563.1_39724001_2 - 4.3 5.0 9.4 0.49 8.1 4.5 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Bacillus_HBL PF05791.9 001098563.1_39724001_2 - 7 6.2 10.6 0.18 11.4 2.7 2.4 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) FlxA PF14282.4 001098563.1_39724001_2 - 9.2 6.2 19.3 0.093 12.6 7.0 3.2 2 1 1 3 3 3 0 FlxA-like protein GCR PF02155.13 001114186.1_39525001_1 - 3.5e-182 605.4 9.2 4.3e-182 605.1 9.2 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor Hormone_recep PF00104.28 001114186.1_39525001_1 - 8.7e-30 103.7 5.3 4.3e-29 101.4 4.4 2.1 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001114186.1_39525001_1 - 2.8e-28 98.1 13.0 5.2e-28 97.2 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Pheromone PF08015.9 001114186.1_39525001_1 - 0.96 10.4 0.0 0.96 10.4 0.0 3.9 4 0 0 4 4 4 0 Fungal mating-type pheromone WAP PF00095.19 001169024.1_40422001_3 - 2.6e-08 34.0 12.6 2.6e-08 34.0 12.6 2.1 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Peptidase_C14 PF00656.20 001082117.1_37922001_1 - 2e-53 181.8 0.1 2.4e-53 181.5 0.1 1.1 1 0 0 1 1 1 1 Caspase domain DUF846 PF05832.10 001133963.1_43524001_3 - 4.2e-55 185.5 9.6 6.9e-55 184.8 9.6 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) RRM_1 PF00076.20 001131220.1_43523001_2 - 2.3e-25 88.1 0.1 3.9e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001131220.1_43523001_2 - 0.00056 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.3 001131220.1_43523001_2 - 0.0024 17.5 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Costars PF14705.4 001135960.2_49823001_2 - 2e-31 107.9 0.0 3.3e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Costars zf-C2H2 PF00096.24 001133450.1_43527001_1 - 3.3e-61 200.3 122.7 6.1e-06 26.3 1.7 20.3 20 0 0 20 20 20 18 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001133450.1_43527001_1 - 2.3e-52 173.0 121.9 5.2e-08 32.9 0.2 20.3 22 0 0 22 22 21 11 Zinc-finger double domain zf-C2H2_4 PF13894.4 001133450.1_43527001_1 - 6.8e-50 163.3 126.6 0.00049 20.6 0.3 20.3 20 0 0 20 20 20 20 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001133450.1_43527001_1 - 4.7e-27 93.5 43.3 0.0059 16.8 0.0 16.7 18 0 0 18 18 18 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001133450.1_43527001_1 - 3.2e-15 55.5 110.2 0.00055 19.7 1.3 18.7 20 0 0 20 20 20 8 C2H2-type zinc finger zf-met PF12874.5 001133450.1_43527001_1 - 1.5e-11 44.2 71.2 0.00097 19.3 0.0 14.6 16 0 0 16 16 15 5 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 001133450.1_43527001_1 - 1.4e-07 31.0 85.8 0.005 16.4 0.6 15.6 17 0 0 17 17 17 6 zinc-finger C2H2-type zinc_ribbon_15 PF17032.3 001133450.1_43527001_1 - 4.1e-05 24.1 31.6 1.9 9.2 0.1 9.1 8 3 1 9 9 9 3 zinc-ribbon family FYDLN_acid PF09538.8 001133450.1_43527001_1 - 0.00036 21.1 16.0 1.6 9.3 0.1 7.3 3 2 4 7 7 7 2 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.8 001133450.1_43527001_1 - 0.00041 20.3 74.2 0.068 13.2 1.0 13.4 12 3 3 15 15 15 4 Zinc ribbon domain zf-LYAR PF08790.9 001133450.1_43527001_1 - 0.0046 16.7 40.5 3.2 7.6 0.2 12.2 14 0 0 14 14 14 2 LYAR-type C2HC zinc finger C1_4 PF07975.10 001133450.1_43527001_1 - 0.011 15.9 53.5 4.2 7.6 0.0 13.0 8 3 6 15 15 15 0 TFIIH C1-like domain BolA PF01722.16 001133450.1_43527001_1 - 0.044 13.9 16.0 3.8 7.7 0.3 6.7 6 2 2 8 8 7 0 BolA-like protein zinc_ribbon_12 PF11331.6 001133450.1_43527001_1 - 0.076 12.7 0.2 0.076 12.7 0.2 8.8 8 1 1 9 9 9 0 Probable zinc-ribbon domain CpXC PF14353.4 001133450.1_43527001_1 - 0.69 9.8 58.0 0.82 9.6 0.0 13.7 6 4 8 15 15 15 0 CpXC protein zf-RING_7 PF02591.13 001133450.1_43527001_1 - 3.2 7.9 20.8 5.6 7.1 0.1 7.3 7 0 0 7 7 7 0 C4-type zinc ribbon domain RIG-I_C-RD PF11648.6 001133450.1_43527001_1 - 8 6.6 15.1 33 4.7 0.0 5.8 5 0 0 5 5 5 0 C-terminal domain of RIG-I p450 PF00067.20 001173117.1_09925001_1 - 1.1e-128 429.8 2.3 1.2e-128 429.6 2.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DSPc PF00782.18 001197094.1_21022001_1 - 1e-26 93.2 0.0 1.3e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001197094.1_21022001_1 - 0.0011 18.5 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.10 001197094.1_21022001_1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain DSPn PF14671.4 001197094.1_21022001_1 - 0.085 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.4 001197094.1_21022001_1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DZF PF07528.12 001132986.1_43525001_3 - 9e-81 271.0 0.0 1.4e-80 270.4 0.0 1.3 1 0 0 1 1 1 1 DZF domain dsrm PF00035.24 001132986.1_43525001_3 - 2e-25 89.1 0.0 3.1e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.5 001132986.1_43525001_3 - 0.0024 18.0 0.6 4.6 7.4 0.1 3.3 2 2 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 zf-C3HC4_3 PF13920.4 001133390.1_43525001_1 - 3.9e-11 42.5 11.7 3.9e-11 42.5 11.7 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.25 001133390.1_43525001_1 - 0.0016 18.0 1.0 0.54 10.0 0.1 2.9 3 0 0 3 3 3 2 SAP domain Armet PF10208.7 001133390.1_43525001_1 - 0.0016 18.2 10.4 0.035 13.9 0.3 2.4 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding FYVE PF01363.19 001133390.1_43525001_1 - 0.0045 17.0 9.5 0.0045 17.0 9.5 3.0 2 1 0 2 2 2 1 FYVE zinc finger Cwf_Cwc_15 PF04889.10 001133390.1_43525001_1 - 0.11 12.0 5.8 0.21 11.2 5.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Collagen PF01391.16 001131194.2_43525001_1 - 0.0037 16.9 16.5 0.0072 15.9 0.9 2.7 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) MAGE PF01454.17 001131194.2_43525001_2 - 2.9e-22 79.3 4.6 9.9e-22 77.5 0.0 3.0 2 1 0 2 2 2 1 MAGE family AhpC-TSA PF00578.19 001246780.2_14222001_2 - 1.3e-42 144.5 0.0 1.7e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001246780.2_14222001_2 - 4.9e-18 65.1 0.0 6.5e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 001246780.2_14222001_2 - 9e-14 50.9 0.0 1.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin zf-C2H2 PF00096.24 001252582.1_32926001_1 - 1.1e-15 57.0 17.5 0.00011 22.3 1.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001252582.1_32926001_1 - 1e-12 47.7 27.7 3.6e-05 23.9 0.1 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 001252582.1_32926001_1 - 3.1e-05 24.3 26.8 0.18 12.6 0.2 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001252582.1_32926001_1 - 0.00052 20.1 4.5 0.17 12.0 0.9 2.6 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.3 001252582.1_32926001_1 - 0.0046 17.0 9.8 3.3 7.7 0.1 4.1 1 1 3 4 4 4 2 Aberrant zinc-finger zf-C2H2_11 PF16622.3 001252582.1_32926001_1 - 0.0064 16.1 4.4 1.6 8.4 0.4 2.8 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.4 001252582.1_32926001_1 - 0.1 12.4 5.0 0.54 10.1 0.4 3.8 4 1 0 4 4 4 0 zinc-finger of a C2HC-type zf-RRN7 PF11781.6 001252582.1_32926001_1 - 0.42 10.2 5.3 8.4 6.0 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-met PF12874.5 001252582.1_32926001_1 - 1.4 9.3 4.5 15 6.0 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Hist_deacetyl PF00850.17 001246781.1_14227001_1 - 1.4e-80 270.9 2.9 3.4e-80 269.7 0.0 2.2 2 0 0 2 2 2 1 Histone deacetylase domain HDAC4_Gln PF12203.6 001246781.1_14227001_1 - 6.3e-32 109.5 48.8 6.3e-32 109.5 48.8 3.0 2 0 0 2 2 2 1 Glutamine rich N terminal domain of histone deacetylase 4 TFIIA PF03153.11 001246781.1_14227001_1 - 0.014 15.2 36.8 0.37 10.6 16.6 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PGK PF00162.17 001246725.1_14224001_3 - 6.4e-150 499.2 0.4 7.4e-150 499.0 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3172 PF11371.6 001246725.1_14224001_3 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Pannexin_like PF12534.6 133897.2_32926001_2 - 7.2e-151 502.1 2.4 9.9e-151 501.6 2.4 1.2 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.4 133897.2_32926001_2 - 2.5e-24 84.6 29.6 4.3e-09 35.9 2.8 7.3 4 3 3 7 7 7 5 Leucine rich repeat LRR_4 PF12799.5 133897.2_32926001_2 - 5.4e-17 61.4 35.9 0.00074 19.7 0.7 9.4 3 2 6 11 11 11 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 133897.2_32926001_2 - 0.0025 17.2 14.9 0.19 11.1 0.4 4.1 2 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.31 133897.2_32926001_2 - 0.64 10.6 29.4 8.7 7.1 0.0 10.2 11 0 0 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.4 133897.2_32926001_2 - 3.7 7.7 24.2 0.85 9.7 0.1 7.5 9 0 0 9 9 9 0 Leucine Rich repeat ABC_membrane PF00664.21 001243989.1_14229001_3 - 3.3e-166 551.6 35.4 9.7e-94 313.9 12.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001243989.1_14229001_3 - 1.2e-76 255.7 0.7 2.5e-37 128.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.17 001243989.1_14229001_3 - 8.2e-17 61.2 3.6 6.3e-07 28.9 1.5 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.4 001243989.1_14229001_3 - 9e-11 42.3 1.6 0.00026 21.3 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.7 001243989.1_14229001_3 - 3.2e-10 39.3 0.9 5.6e-05 22.0 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.10 001243989.1_14229001_3 - 1.5e-08 34.0 1.2 0.0004 19.6 0.0 3.5 4 0 0 4 4 4 2 Zeta toxin AAA_22 PF13401.4 001243989.1_14229001_3 - 6.7e-08 32.8 1.9 0.019 15.1 0.2 3.3 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.14 001243989.1_14229001_3 - 2.3e-07 30.7 0.2 0.029 14.2 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 G-alpha PF00503.18 001243989.1_14229001_3 - 4e-07 29.4 0.1 0.0093 15.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.27 001243989.1_14229001_3 - 4.2e-07 30.3 3.6 0.071 13.4 0.1 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.13 001243989.1_14229001_3 - 1.3e-06 27.5 0.0 0.0063 15.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_5 PF07728.12 001243989.1_14229001_3 - 2e-06 27.7 0.6 0.11 12.4 0.0 3.6 3 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.4 001243989.1_14229001_3 - 5.1e-06 26.0 1.4 0.057 13.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.4 001243989.1_14229001_3 - 8.8e-06 25.4 0.0 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.4 001243989.1_14229001_3 - 2.4e-05 24.2 0.1 0.055 13.4 0.0 3.5 2 2 0 2 2 2 1 AAA domain APS_kinase PF01583.18 001243989.1_14229001_3 - 5.8e-05 22.9 0.3 0.35 10.6 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_30 PF13604.4 001243989.1_14229001_3 - 0.0002 21.0 2.7 0.12 11.9 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.4 001243989.1_14229001_3 - 0.00028 21.2 0.0 0.52 10.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.4 001243989.1_14229001_3 - 0.00033 20.7 3.7 0.7 10.0 0.3 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF815 PF05673.11 001243989.1_14229001_3 - 0.00042 19.4 0.1 0.25 10.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.4 001243989.1_14229001_3 - 0.00044 20.4 0.3 5.1 7.2 0.0 3.9 3 1 1 4 4 3 0 AAA domain ATP-synt_ab PF00006.23 001243989.1_14229001_3 - 0.00054 19.5 1.1 1.8 8.0 0.0 3.1 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.15 001243989.1_14229001_3 - 0.00061 19.8 2.4 0.58 10.0 0.1 2.9 3 0 0 3 3 3 2 Domain of unknown function DUF87 PRK PF00485.16 001243989.1_14229001_3 - 0.00084 19.0 0.0 0.98 9.0 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.4 001243989.1_14229001_3 - 0.0011 18.6 0.0 0.35 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.20 001243989.1_14229001_3 - 0.0011 19.1 0.0 3.3 8.0 0.0 3.2 2 0 0 2 2 2 1 RNA helicase AAA_21 PF13304.4 001243989.1_14229001_3 - 0.0012 18.6 0.0 5.5 6.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.4 001243989.1_14229001_3 - 0.0049 16.9 0.0 5.6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.9 001243989.1_14229001_3 - 0.0063 16.5 0.0 3.2 7.7 0.0 2.7 3 0 0 3 3 2 1 tRNA ligase kinase domain NACHT PF05729.10 001243989.1_14229001_3 - 0.0091 15.8 0.3 2.4 7.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.4 001243989.1_14229001_3 - 0.022 14.2 0.2 4.4 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.15 001243989.1_14229001_3 - 0.026 14.1 1.6 61 3.2 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein Mg_chelatase PF01078.19 001243989.1_14229001_3 - 0.04 13.2 0.0 6.6 5.9 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.13 001243989.1_14229001_3 - 0.049 13.4 1.4 0.84 9.4 0.1 2.9 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.20 001243989.1_14229001_3 - 0.056 12.3 0.8 8.2 5.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.7 001243989.1_14229001_3 - 0.064 12.9 1.2 10 5.7 0.1 3.1 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Dala_Dala_lig_N PF01820.19 001243989.1_14229001_3 - 0.072 13.1 0.2 1 9.4 0.0 2.9 3 0 0 3 3 2 0 D-ala D-ala ligase N-terminus MMR_HSR1 PF01926.21 001243989.1_14229001_3 - 0.083 12.9 0.0 8.8 6.3 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.4 001243989.1_14229001_3 - 0.09 13.1 0.2 11 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain Spore_YhaL PF14147.4 001243989.1_14229001_3 - 0.15 11.6 0.0 2.9 7.5 0.1 2.8 2 0 0 2 2 2 0 Sporulation protein YhaL RuvX PF03652.13 001243989.1_14229001_3 - 0.19 12.0 0.9 1.9 8.7 0.2 2.4 2 0 0 2 2 2 0 Holliday junction resolvase DPM3 PF08285.9 001243989.1_14229001_3 - 2.1 8.5 5.5 3.5 7.7 0.4 3.3 3 0 0 3 3 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Ofd1_CTDD PF10637.7 001324360.1_26227001_1 - 1.6e-40 139.0 0.9 4.4e-38 131.0 0.6 2.4 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.4 001324360.1_26227001_1 - 6.5e-35 119.6 0.1 3.6e-30 104.3 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.4 001324360.1_26227001_1 - 6.9e-16 58.8 0.0 1.3e-13 51.5 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.14 001133261.1_43528001_3 - 7.6e-33 113.8 52.1 7.3e-24 84.2 24.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glypican PF01153.17 001135737.1_39725001_3 - 2e-184 614.4 0.0 2.4e-184 614.1 0.0 1.0 1 0 0 1 1 1 1 Glypican Lipase PF00151.17 001009394.1_39524001_1 - 1.4e-132 441.9 0.0 2e-132 441.4 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.21 001009394.1_39524001_1 - 3.1e-23 82.4 0.5 5.5e-23 81.6 0.5 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.5 001009394.1_39524001_1 - 2.1e-05 25.1 0.4 2.1e-05 25.1 0.4 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001009394.1_39524001_1 - 0.00036 20.1 0.1 0.00056 19.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PX PF00787.22 001133205.1_43523001_3 - 1.3e-27 95.8 0.0 2.6e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 PX domain Cofilin_ADF PF00241.18 001025320.2_06523001_1 - 1.8e-41 141.1 3.1 2e-21 76.3 0.2 2.4 3 0 0 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein 7tm_1 PF00001.19 001172957.2_09923001_1 - 1.1e-40 139.5 11.6 1.1e-40 139.5 11.6 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Colicin_V PF02674.14 001172957.2_09923001_1 - 0.039 13.8 1.8 1.5 8.7 0.1 3.1 3 0 0 3 3 3 0 Colicin V production protein DUF788 PF05620.9 001283197.1_29524001_2 - 0.031 14.1 2.5 0.043 13.6 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Cpn60_TCP1 PF00118.22 001283197.1_29524001_3 - 3.8e-147 490.7 11.7 4.5e-147 490.5 11.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2529 PF10740.7 001283197.1_29524001_3 - 0.0055 16.2 0.3 0.018 14.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2529) IL8 PF00048.18 001281311.1_16221001_1 - 1.4e-14 53.9 0.4 1.8e-14 53.5 0.4 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like zf-RING_UBOX PF13445.4 001280113.1_35723001_1 - 2.5e-12 46.5 4.9 4.2e-12 45.7 3.6 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001280113.1_35723001_1 - 2.6e-11 43.3 8.6 7.3e-11 41.9 8.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING SPRY PF00622.26 001280113.1_35723001_1 - 7.4e-10 38.9 0.1 1.6e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 SPRY domain zf-C3HC4 PF00097.23 001280113.1_35723001_1 - 2.5e-09 36.7 7.9 6.8e-09 35.3 7.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.22 001280113.1_35723001_1 - 7.2e-08 32.3 21.2 1.5e-07 31.3 4.3 3.4 3 1 0 3 3 3 2 B-box zinc finger zf-RING_2 PF13639.4 001280113.1_35723001_1 - 2.1e-07 30.9 8.1 2.1e-07 30.9 8.1 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.4 001280113.1_35723001_1 - 2.8e-07 30.1 6.4 2.8e-07 30.1 6.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001280113.1_35723001_1 - 3.2e-07 30.0 9.1 9.9e-07 28.4 9.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001280113.1_35723001_1 - 4.9e-07 29.5 6.5 4.9e-07 29.5 6.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain TMF_TATA_bd PF12325.6 001280113.1_35723001_1 - 4.9e-06 26.6 3.4 4.9e-06 26.6 3.4 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding U-box PF04564.13 001280113.1_35723001_1 - 0.00093 19.2 0.0 0.0025 17.8 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-RING_10 PF16685.3 001280113.1_35723001_1 - 0.0094 15.9 5.2 0.0094 15.9 5.2 2.0 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-UDP PF14569.4 001280113.1_35723001_1 - 0.026 14.5 2.3 0.046 13.7 0.7 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.4 001280113.1_35723001_1 - 0.097 12.3 6.9 0.87 9.2 7.2 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.6 001280113.1_35723001_1 - 0.28 10.9 4.5 0.93 9.2 4.5 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.4 001280113.1_35723001_1 - 0.49 10.2 16.0 0.22 11.3 10.9 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 AAA_11 PF13086.4 001280113.1_35723001_1 - 0.5 9.9 5.5 0.74 9.4 5.5 1.2 1 0 0 1 1 1 0 AAA domain Baculo_IE-1 PF05290.9 001280113.1_35723001_1 - 0.53 10.1 4.4 0.43 10.4 1.1 2.4 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.4 001280113.1_35723001_1 - 0.95 9.2 6.0 0.58 9.9 3.3 2.1 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Fib_alpha PF08702.8 001280113.1_35723001_1 - 1.5 8.9 9.7 13 5.8 0.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.12 001280113.1_35723001_1 - 1.7 8.3 13.7 3.5 7.2 13.7 1.5 1 0 0 1 1 1 0 IncA protein zf-rbx1 PF12678.5 001280113.1_35723001_1 - 3.8 7.8 12.0 1.1 9.5 7.4 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain SpecificRecomb PF10136.7 001280113.1_35723001_1 - 5.1 5.1 6.5 8 4.5 6.5 1.2 1 0 0 1 1 1 0 Site-specific recombinase ApoLp-III PF07464.9 001280113.1_35723001_1 - 6.7 6.7 14.2 6.6 6.7 6.1 2.7 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Peptidase_C14 PF00656.20 001281582.1_31325001_1 - 1.5e-53 182.2 0.1 2.1e-53 181.7 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Gp_dh_C PF02800.18 001244854.2_14223001_1 - 1.3e-70 235.9 0.0 1.9e-70 235.4 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001244854.2_14223001_1 - 1.2e-39 134.6 0.3 2.1e-39 133.8 0.3 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001244854.2_14223001_1 - 0.046 13.7 0.1 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus OstA PF03968.12 001244854.2_14223001_1 - 0.15 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 OstA-like protein MHC_I PF00129.16 001279551.1_24223001_1 - 7.7e-93 308.9 2.0 1.1e-92 308.4 2.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001279551.1_24223001_1 - 5.3e-17 61.9 0.1 1.3e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001279551.1_24223001_1 - 4.4e-16 58.4 9.6 8e-16 57.5 9.6 1.5 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001279551.1_24223001_1 - 1.9e-06 28.2 1.9 0.0063 17.0 0.1 3.0 1 1 1 2 2 2 2 Immunoglobulin domain DUF202 PF02656.13 001279551.1_24223001_1 - 0.0014 18.9 0.2 0.48 10.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF202) ig PF00047.23 001279551.1_24223001_1 - 0.0018 18.2 0.4 0.0038 17.2 0.4 1.6 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001279551.1_24223001_1 - 0.0043 17.0 0.4 0.0043 17.0 0.4 1.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain MHC_I_3 PF16497.3 001279551.1_24223001_1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 MHC-I family domain DUF2755 PF10954.6 001279551.1_24223001_1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) DUF4006 PF13179.4 001282362.1_11322001_2 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Aldo_ket_red PF00248.19 001170956.1_37924001_1 - 1.1e-70 237.9 0.0 1.4e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_q6 PF01058.20 001279585.1_24222001_1 - 5.2e-24 84.4 0.1 7.6e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit FKBP_C PF00254.26 001280014.1_46723001_3 - 5.3e-49 164.4 0.0 2.2e-30 104.7 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.26 001280014.1_46723001_3 - 3.4e-18 64.5 4.7 7.4e-08 31.8 0.8 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.15 001280014.1_46723001_3 - 2.7e-13 48.8 3.9 0.00013 21.6 0.5 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.4 001280014.1_46723001_3 - 8.9e-11 41.0 2.9 6.3e-05 22.8 0.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.4 001280014.1_46723001_3 - 2.3e-08 34.0 0.4 0.057 14.0 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.4 001280014.1_46723001_3 - 8e-08 32.6 1.4 0.021 15.2 0.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.4 001280014.1_46723001_3 - 1.5e-06 28.3 0.2 0.00055 20.1 0.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.4 001280014.1_46723001_3 - 6.9e-06 25.6 0.8 0.00019 21.1 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001280014.1_46723001_3 - 4.1e-05 23.4 1.1 0.016 15.1 0.2 2.5 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.4 001280014.1_46723001_3 - 0.00028 20.4 1.3 0.079 12.5 0.0 3.2 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.4 001280014.1_46723001_3 - 0.0006 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001280014.1_46723001_3 - 0.0025 17.9 4.5 0.069 13.2 0.3 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.4 001280014.1_46723001_3 - 0.0027 18.2 0.1 0.81 10.5 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.6 001280014.1_46723001_3 - 0.0042 15.9 5.2 0.48 9.1 1.6 2.5 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 PknG_TPR PF16918.3 001280014.1_46723001_3 - 0.0075 14.9 0.1 0.011 14.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_16 PF13432.4 001280014.1_46723001_3 - 0.011 16.3 0.1 2.4 8.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.4 001280014.1_46723001_3 - 0.017 14.9 0.3 0.083 12.7 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.15 001281764.1_16229001_1 - 2.8e-93 311.8 0.0 4.3e-93 311.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sema PF01403.17 001281764.1_16229001_1 - 4.1e-61 206.9 3.0 6.4e-61 206.3 3.0 1.2 1 0 0 1 1 1 1 Sema domain Pkinase PF00069.23 001281764.1_16229001_1 - 7.9e-40 136.7 0.0 1.3e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.22 001281764.1_16229001_1 - 1.9e-38 130.2 10.5 4.4e-13 49.0 0.4 4.7 4 0 0 4 4 4 4 IPT/TIG domain PSI PF01437.23 001281764.1_16229001_1 - 2.7e-05 24.5 14.3 2.7e-05 24.5 14.3 2.7 2 0 0 2 2 2 1 Plexin repeat Kinase-like PF14531.4 001281764.1_16229001_1 - 0.00032 20.0 0.0 0.00055 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Linker_histone PF00538.17 001281764.1_16229001_1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family DUF1049 PF06305.9 001281764.1_16229001_1 - 0.13 12.0 0.6 0.29 10.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) wnt PF00110.17 001281763.1_16226001_2 - 5.6e-121 403.6 25.1 6.8e-121 403.4 25.1 1.1 1 0 0 1 1 1 1 wnt family Tubulin PF00091.23 001243978.1_14224001_2 - 7e-69 231.9 0.0 9.3e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001243978.1_14224001_2 - 2.7e-51 172.9 0.0 4.2e-51 172.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001243978.1_14224001_2 - 0.0018 17.9 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Ribosomal_L21e PF01157.16 001282366.1_11322001_2 - 1.6e-50 168.8 9.4 1.6e-50 168.8 9.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e CFTR_R PF14396.4 001278757.1_09929001_2 - 1.8e-98 328.1 4.0 3.3e-98 327.3 4.0 1.4 1 0 0 1 1 1 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain ABC_membrane PF00664.21 001278757.1_09929001_2 - 3.3e-93 312.1 44.4 2.2e-50 171.7 21.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001278757.1_09929001_2 - 3.2e-59 199.2 0.1 3.2e-33 115.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.17 001278757.1_09929001_2 - 4e-08 32.8 0.0 0.018 14.4 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.4 001278757.1_09929001_2 - 2.2e-07 30.9 2.0 0.043 13.5 0.0 3.7 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.4 001278757.1_09929001_2 - 2.2e-06 27.2 0.7 0.00072 19.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.18 001278757.1_09929001_2 - 6.8e-06 25.2 0.0 0.13 11.2 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.14 001278757.1_09929001_2 - 1.5e-05 24.8 1.0 0.015 15.1 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.4 001278757.1_09929001_2 - 2.8e-05 24.4 0.0 0.1 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.15 001278757.1_09929001_2 - 0.00041 20.3 3.9 0.063 13.2 0.1 2.9 3 0 0 3 3 2 2 Domain of unknown function DUF87 Zeta_toxin PF06414.10 001278757.1_09929001_2 - 0.00043 19.5 0.4 0.097 11.8 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.4 001278757.1_09929001_2 - 0.00088 19.4 0.4 2.8 8.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.21 001278757.1_09929001_2 - 0.0009 19.2 0.4 0.33 10.9 0.1 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.10 001278757.1_09929001_2 - 0.0016 18.2 0.5 2.3 8.0 0.0 2.9 2 0 0 2 2 2 2 NACHT domain ArgK PF03308.14 001278757.1_09929001_2 - 0.0041 16.0 0.7 0.021 13.7 0.1 2.2 2 0 0 2 2 2 1 ArgK protein NTPase_1 PF03266.13 001278757.1_09929001_2 - 0.012 15.4 0.2 0.71 9.6 0.0 2.9 3 0 0 3 3 3 0 NTPase MobB PF03205.12 001278757.1_09929001_2 - 0.02 14.7 1.5 7.3 6.4 0.1 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.4 001278757.1_09929001_2 - 0.023 14.3 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.11 001278757.1_09929001_2 - 0.026 14.6 0.1 4.8 7.3 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.15 001278757.1_09929001_2 - 0.027 14.4 0.4 9.5 6.1 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.17 001278757.1_09929001_2 - 0.042 13.3 2.0 2.9 7.3 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.4 001278757.1_09929001_2 - 0.05 13.8 0.1 18 5.5 0.0 3.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.16 001278757.1_09929001_2 - 0.051 12.8 0.6 4.5 6.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.4 001278757.1_09929001_2 - 0.098 13.0 16.0 0.88 9.9 0.1 4.3 4 0 0 4 4 4 0 AAA domain TrwB_AAD_bind PF10412.7 001278757.1_09929001_2 - 0.13 11.0 1.2 5.2 5.7 0.1 2.9 2 1 1 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.21 001278757.1_09929001_2 - 0.51 10.2 2.1 14 5.6 0.1 3.0 2 1 0 2 2 2 0 Dynamin family Peptidase_C14 PF00656.20 001279966.1_46722001_1 - 3.8e-54 184.1 0.2 4.6e-54 183.8 0.2 1.1 1 0 0 1 1 1 1 Caspase domain Ribosomal_L11_N PF03946.12 001282370.1_11322001_1 - 2.1e-26 91.3 0.1 4e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.17 001282370.1_11322001_1 - 4.1e-19 68.7 0.1 6.5e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ITI_HC_C PF06668.10 001281662.1_31327001_1 - 3.2e-71 238.8 0.0 5.9e-71 237.9 0.0 1.5 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.8 001281662.1_31327001_1 - 1.5e-31 108.8 0.4 2.8e-31 107.9 0.4 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.26 001281662.1_31327001_1 - 3.2e-22 79.5 2.2 5.4e-22 78.7 2.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.4 001281662.1_31327001_1 - 1.1e-18 67.5 0.0 1.9e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.4 001281662.1_31327001_1 - 4.6e-12 46.4 0.2 1.6e-11 44.7 0.2 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.12 001281662.1_31327001_1 - 0.00019 20.8 0.0 0.00042 19.6 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein SH3_8 PF13457.4 001281662.1_31327001_1 - 0.037 14.5 0.1 0.46 11.0 0.1 2.5 2 0 0 2 2 2 0 SH3-like domain DUF2201 PF09967.7 001281662.1_31327001_1 - 0.047 13.7 0.5 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 VWA-like domain (DUF2201) SWIB PF02201.16 001281662.1_31327001_1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain Transthyretin PF00576.19 001280678.1_48822001_1 - 3.5e-18 66.2 0.0 4.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Arrestin_N PF00339.27 001282266.1_26723001_3 - 6.2e-35 120.3 0.0 8.9e-33 113.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 001282266.1_26723001_3 - 4.3e-17 62.6 0.3 7.2e-17 61.9 0.3 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain CBM49 PF09478.8 001282266.1_26723001_3 - 6.4e-05 23.0 0.7 0.00011 22.4 0.7 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 V-set PF07686.15 001284856.1_29525001_1 - 1e-10 41.6 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001284856.1_29525001_1 - 4.5e-05 23.9 0.0 0.00019 21.9 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001284856.1_29525001_1 - 5.7e-05 23.0 0.0 0.00019 21.3 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.23 001284856.1_29525001_1 - 0.00063 19.7 0.0 0.0082 16.2 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 001257242.1_08022001_1 - 2.9e-11 43.3 0.0 3.9e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 001257242.1_08022001_1 - 2.9e-05 24.0 0.0 0.00031 20.7 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001257242.1_08022001_1 - 6.7e-05 22.7 0.0 0.00022 21.1 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 001257242.1_08022001_1 - 9.8e-05 22.8 0.0 0.0005 20.5 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Longin PF13774.4 001257242.1_08022001_1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain IL12 PF03039.12 001285638.1_09022001_1 - 1.6e-112 374.0 6.6 1.8e-112 373.9 6.6 1.0 1 0 0 1 1 1 1 Interleukin-12 alpha subunit DCX PF03607.15 001280013.1_46729001_1 - 3.4e-35 119.8 0.0 2.2e-20 72.4 0.0 2.8 2 0 0 2 2 2 2 Doublecortin p450 PF00067.20 001281373.1_31324001_2 - 1.7e-100 336.8 0.0 2.2e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec8_exocyst PF04048.12 001281373.1_31324001_2 - 0.03 14.1 0.7 0.06 13.1 0.7 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Pkinase PF00069.23 001282270.1_26727001_2 - 2.1e-59 200.9 0.0 2.7e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001282270.1_26727001_2 - 1.4e-30 106.3 0.0 2.3e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.17 001282270.1_26727001_2 - 2.4e-16 59.9 0.9 4.9e-16 58.9 0.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.4 001282270.1_26727001_2 - 1.7e-05 24.2 0.0 2.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ribosomal_L6e PF01159.17 001282363.1_11322001_3 - 2e-44 150.4 1.2 2e-44 150.4 1.2 3.5 4 0 0 4 4 4 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.13 001282363.1_11322001_3 - 6.9e-34 115.7 12.0 6.9e-34 115.7 12.0 3.4 4 0 0 4 4 4 1 Ribosomal protein L6, N-terminal domain 7tm_1 PF00001.19 001267759.1_08023001_2 - 5.4e-43 147.0 0.7 6.8e-43 146.7 0.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ribosomal_L5 PF00281.17 001282371.1_11322001_1 - 4.7e-23 81.2 0.0 2.4e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.19 001282371.1_11322001_1 - 1.4e-21 76.3 0.0 2.2e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus IL8 PF00048.18 001280642.1_52221001_1 - 8e-18 64.2 1.2 1.3e-17 63.5 1.2 1.4 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like TNF PF00229.16 001280615.1_52224001_3 - 4.5e-39 133.2 0.0 7e-39 132.5 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family LRR_8 PF13855.4 001279236.1_39625001_1 - 3e-34 116.4 48.0 1e-13 50.7 7.4 7.8 5 2 2 7 7 7 7 Leucine rich repeat TIR PF01582.18 001279236.1_39625001_1 - 1e-21 77.4 0.6 1e-21 77.4 0.6 1.8 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.5 001279236.1_39625001_1 - 2e-19 69.1 49.8 0.00086 19.5 4.6 9.3 7 1 2 10 10 10 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001279236.1_39625001_1 - 1.1e-09 38.4 0.1 2.9e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.4 001279236.1_39625001_1 - 6.6e-09 35.4 15.6 6.4e-05 22.4 0.4 4.5 2 2 1 4 4 4 2 Leucine-rich repeat LRR_5 PF13306.4 001279236.1_39625001_1 - 1.9e-06 27.7 2.0 1.9e-06 27.7 2.0 4.3 3 1 2 5 5 5 3 Leucine rich repeats (6 copies) LRRCT PF01463.22 001279236.1_39625001_1 - 0.00019 21.6 0.2 0.00073 19.8 0.2 2.1 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001279236.1_39625001_1 - 0.00043 20.2 38.6 0.11 12.9 0.6 10.7 11 1 0 11 11 11 3 Leucine Rich Repeat DUF1863 PF08937.9 001279236.1_39625001_1 - 0.17 12.0 0.4 0.76 10.0 0.4 2.0 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) FOXO_KIX_bdg PF16675.3 001282256.1_26726001_2 - 1.7e-30 104.9 3.5 1.7e-30 104.9 3.5 2.4 3 0 0 3 3 3 1 KIX-binding domain of forkhead box O, CR2 Forkhead PF00250.16 001282256.1_26726001_2 - 5e-25 87.5 0.1 9.6e-25 86.6 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain FOXO-TAD PF16676.3 001282256.1_26726001_2 - 2e-19 69.5 7.9 3.6e-19 68.8 7.9 1.4 1 0 0 1 1 1 1 Transactivation domain of FOXO protein family TAL_FSA PF00923.17 001246775.1_14223001_2 - 1.9e-102 342.3 0.1 2.2e-102 342.1 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase 7tm_1 PF00001.19 001279992.1_46724001_1 - 2.1e-79 266.4 2.3 2.8e-79 266.0 2.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001279992.1_46724001_1 - 6.1e-08 32.2 11.3 3.7e-07 29.7 2.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001279992.1_46724001_1 - 2.7e-06 26.8 5.0 2.7e-06 26.8 5.0 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001279992.1_46724001_1 - 2.7e-05 23.9 1.5 2.7e-05 23.9 1.5 2.4 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srbc PF10316.7 001279992.1_46724001_1 - 0.0022 17.4 7.2 0.0022 17.4 7.2 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2693 PF10902.6 001279992.1_46724001_1 - 0.15 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) DUF2417 PF10329.7 001279992.1_46724001_1 - 2.2 7.5 9.5 7.6 5.7 7.0 2.5 2 1 0 2 2 2 0 Region of unknown function (DUF2417) TPR_2 PF07719.15 001279960.1_46723001_1 - 3.9e-10 38.9 1.3 0.0012 18.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.26 001279960.1_46723001_1 - 5.3e-05 23.3 0.0 0.00025 21.2 0.0 2.0 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.26 001279960.1_46723001_1 - 6.1e-05 22.5 1.4 0.9 9.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.4 001279960.1_46723001_1 - 0.00023 21.0 0.2 0.16 12.1 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.4 001279960.1_46723001_1 - 0.00058 19.4 1.8 0.0012 18.3 0.2 2.1 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.4 001279960.1_46723001_1 - 0.002 18.2 0.2 0.49 10.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001279960.1_46723001_1 - 0.014 15.4 2.9 0.18 11.9 1.5 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 F-box-like_2 PF13013.4 001279960.1_46723001_1 - 0.047 13.6 0.3 0.09 12.7 0.3 1.4 1 0 0 1 1 1 0 F-box-like domain TPR_10 PF13374.4 001279960.1_46723001_1 - 0.27 11.1 2.9 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat XPG_N PF00752.15 001285179.1_29525001_1 - 1.2e-37 128.3 0.0 2.2e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.16 001285179.1_29525001_1 - 3.8e-30 104.0 0.0 7.4e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.18 001285179.1_29525001_1 - 7.6e-07 29.5 0.0 1.9e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.4 001285179.1_29525001_1 - 0.097 13.2 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain zf-CSL PF05207.11 001244538.1_14221001_1 - 7.6e-25 86.3 2.0 1e-24 85.8 2.0 1.2 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.13 001244538.1_14221001_1 - 0.055 13.5 0.5 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain Acetyltransf_1 PF00583.23 001281591.1_31322001_1 - 3.9e-14 52.8 0.0 5.7e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.5 001281591.1_31322001_1 - 2.9e-06 27.5 0.0 5.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.5 001281591.1_31322001_1 - 0.00026 20.8 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.8 001281591.1_31322001_1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein XAP5 PF04921.12 001284132.1_29524001_3 - 6.6e-78 261.7 12.3 6.6e-78 261.7 12.3 1.8 1 1 1 2 2 2 1 XAP5, circadian clock regulator IL12p40_C PF10420.7 001285700.1_09022001_1 - 4.4e-22 78.2 4.7 5.4e-22 77.9 0.7 2.4 2 0 0 2 2 2 1 Cytokine interleukin-12p40 C-terminus Ig_5 PF16681.3 001285700.1_09022001_1 - 1.3e-06 28.6 2.2 1.4e-05 25.3 0.1 2.7 2 1 1 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.4 001285700.1_09022001_1 - 8.2e-06 26.2 4.9 2.3e-05 24.8 0.2 3.0 3 0 0 3 3 3 1 Immunoglobulin domain fn3 PF00041.19 001285700.1_09022001_1 - 1.4e-05 25.2 0.3 0.00029 21.0 0.3 2.8 2 0 0 2 2 2 1 Fibronectin type III domain Ig_4 PF16680.3 001285700.1_09022001_1 - 1.8e-05 24.9 2.2 0.0003 21.0 0.0 2.9 2 1 1 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_2 PF13895.4 001285700.1_09022001_1 - 8.6e-05 22.7 0.3 0.0025 18.0 0.0 2.8 1 1 1 2 2 2 1 Immunoglobulin domain I-set PF07679.14 001285700.1_09022001_1 - 0.066 13.1 4.2 0.24 11.4 0.2 3.7 4 2 0 4 4 4 0 Immunoglobulin I-set domain V-set PF07686.15 001285700.1_09022001_1 - 0.09 12.8 3.3 26 4.9 0.0 3.7 3 1 0 4 4 4 0 Immunoglobulin V-set domain FOXP-CC PF16159.3 001279537.1_24225001_1 - 3.3e-35 120.4 4.2 3.3e-35 120.4 4.2 4.8 3 1 2 5 5 5 1 FOXP coiled-coil domain Forkhead PF00250.16 001279537.1_24225001_1 - 2.5e-28 98.1 0.2 1.1e-27 96.1 0.2 2.1 1 0 0 1 1 1 1 Forkhead domain Plasmodium_Vir PF05795.9 001279537.1_24225001_1 - 0.38 10.0 11.3 0.85 8.8 9.3 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein CobT PF06213.10 001279537.1_24225001_1 - 0.43 9.8 33.3 0.78 8.9 33.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.10 001279537.1_24225001_1 - 0.68 9.6 24.6 1.6 8.4 24.6 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.3 001279537.1_24225001_1 - 1.2 8.3 14.7 2.6 7.3 14.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1764 PF08576.8 001279537.1_24225001_1 - 3.6 8.4 17.7 14 6.5 17.7 2.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TT_ORF1 PF02956.12 001279537.1_24225001_1 - 6.2 5.2 25.5 10 4.5 25.5 1.2 1 0 0 1 1 1 0 TT viral orf 1 hDGE_amylase PF14701.4 001279537.1_24225001_1 - 6.3 5.6 22.2 14 4.5 22.2 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Apt1 PF10351.7 001279537.1_24225001_2 - 0.42 9.3 19.5 0.56 8.9 19.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1510 PF07423.9 001279537.1_24225001_2 - 4.6 6.5 8.6 6.5 6.0 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PET PF06297.12 001281762.1_16223001_2 - 2.7e-41 139.6 3.5 4.6e-41 138.9 3.5 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.20 001281762.1_16223001_2 - 1.4e-27 95.5 58.0 4.4e-14 52.3 8.6 4.4 4 1 1 5 5 5 3 LIM domain Ig_Tie2_1 PF10430.7 001281762.1_16223001_2 - 0.068 13.5 0.5 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 Serpin PF00079.18 001312684.1_26723001_1 - 7e-115 384.1 1.3 7.9e-115 384.0 1.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1280 PF06918.12 001312684.1_26723001_1 - 0.023 14.2 0.9 0.042 13.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1280) IL2 PF00715.15 001308532.1_02621001_1 - 2.1e-80 267.6 4.8 2.4e-80 267.4 4.8 1.0 1 0 0 1 1 1 1 Interleukin 2 Plasmid_RAQPRD PF09686.8 001308532.1_02621001_1 - 0.012 15.7 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Desmo_N PF06771.9 001308532.1_02621001_1 - 0.11 12.7 0.3 1.8 8.8 0.1 2.2 1 1 0 2 2 2 0 Viral Desmoplakin N-terminus LRR_8 PF13855.4 001290891.1_07325001_1 - 3.6e-34 116.2 52.3 2.1e-13 49.7 6.1 8.2 6 3 2 8 8 8 7 Leucine rich repeat TIR PF01582.18 001290891.1_07325001_1 - 9.8e-22 77.5 0.7 2.1e-21 76.4 0.7 1.6 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001290891.1_07325001_1 - 1.3e-20 72.9 49.7 2.7e-05 24.2 2.1 8.8 7 1 2 9 9 9 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001290891.1_07325001_1 - 7.8e-10 38.9 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001290891.1_07325001_1 - 7.7e-06 25.4 19.3 0.0012 18.2 0.6 4.4 2 2 3 5 5 5 3 Leucine-rich repeat LRRCT PF01463.22 001290891.1_07325001_1 - 0.0029 17.9 0.4 0.016 15.6 0.4 2.4 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001290891.1_07325001_1 - 0.011 16.0 42.7 0.1 13.0 1.0 11.2 10 2 0 10 10 10 0 Leucine Rich Repeat LRR_6 PF13516.4 001290891.1_07325001_1 - 0.028 14.3 30.9 1.2 9.2 0.6 8.8 10 0 0 10 10 10 0 Leucine Rich repeat DUF1863 PF08937.9 001290891.1_07325001_1 - 0.15 12.3 0.9 0.61 10.3 0.9 2.0 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) IL8 PF00048.18 001305922.1_29721001_3 - 1.9e-17 63.0 0.3 4.5e-17 61.8 0.3 1.6 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like LPAM_1 PF08139.10 001305922.1_29721001_3 - 0.056 13.8 0.4 0.27 11.7 0.2 2.0 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Carb_anhydrase PF00194.19 001305891.1_29723001_1 - 5.6e-94 314.3 0.1 6.7e-94 314.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Casein PF00363.16 001303563.1_08523001_1 - 9.7e-20 70.9 15.8 9.7e-20 70.9 15.8 3.2 2 1 1 3 3 3 1 Casein TNFR_c6 PF00020.16 001305971.1_10823001_1 - 5.3e-17 61.8 38.7 2e-09 37.6 9.1 3.8 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region Death PF00531.20 001305971.1_10823001_1 - 1.9e-16 59.8 0.1 4.1e-16 58.8 0.0 1.6 2 0 0 2 2 2 1 Death domain Peptidase_C8 PF03569.11 001305971.1_10823001_1 - 0.0019 17.7 0.4 0.0078 15.6 0.4 1.8 2 0 0 2 2 2 1 Peptidase family C8 Stn1_C PF12659.5 001305971.1_10823001_1 - 0.054 13.3 0.1 0.17 11.7 0.1 1.8 1 1 1 2 2 2 0 Telomere capping C-terminal wHTH Lys PF00062.18 001290067.1_28322001_1 - 2.1e-55 186.2 2.5 2.7e-55 185.8 2.5 1.2 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.18 001290067.1_28322001_1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain 7tm_1 PF00001.19 001309022.1_29723001_1 - 6.5e-47 159.9 24.1 1.1e-46 159.1 24.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001309022.1_29723001_1 - 1.4e-06 27.8 23.9 1.8e-06 27.4 23.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001309022.1_29723001_1 - 0.071 12.3 20.9 0.031 13.5 18.2 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001309022.1_29723001_1 - 1.7 8.1 20.9 11 5.5 20.9 2.4 1 1 0 1 1 1 0 Olfactory receptor EF-hand_1 PF00036.30 001310577.1_31322001_1 - 1.3e-16 58.6 24.5 0.00088 18.5 0.4 7.5 7 0 0 7 7 7 6 EF hand EF-hand_7 PF13499.4 001310577.1_31322001_1 - 1.6e-16 60.4 21.9 0.0001 22.5 0.7 4.5 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001310577.1_31322001_1 - 2.6e-14 51.7 19.1 0.003 17.2 0.1 7.3 7 0 0 7 7 7 5 EF-hand domain EF-hand_5 PF13202.4 001310577.1_31322001_1 - 1.6e-12 46.2 32.7 0.0025 17.1 0.6 7.1 8 0 0 8 8 8 6 EF hand EF-hand_8 PF13833.4 001310577.1_31322001_1 - 1.5e-08 34.2 10.8 0.00079 19.0 0.0 4.9 5 0 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001310577.1_31322001_1 - 0.014 15.5 15.3 0.66 10.2 0.4 4.1 2 2 2 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region C2 PF00168.28 001301370.1_32929001_3 - 2.4e-16 59.8 0.0 3.4e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 C2 domain GHBP PF12772.5 001302931.1_46724001_1 - 1e-125 419.1 1.7 1.4e-125 418.7 1.7 1.1 1 0 0 1 1 1 1 Growth hormone receptor binding EpoR_lig-bind PF09067.8 001302931.1_46724001_1 - 2.5e-10 40.4 1.5 2.5e-10 40.4 1.5 2.1 3 0 0 3 3 3 1 Erythropoietin receptor, ligand binding fn3 PF00041.19 001302931.1_46724001_1 - 1.9e-06 28.0 0.2 4.5e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Transthyretin PF00576.19 001291885.1_21222001_1 - 3.5e-20 72.6 0.1 4.9e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family C1-set PF07654.13 001308516.1_02622001_2 - 4.2e-23 81.5 0.1 6.1e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001308516.1_02622001_2 - 0.00082 19.8 0.1 0.0018 18.7 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.14 001308516.1_02622001_2 - 0.024 14.6 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain MRAP PF15183.4 001308516.1_02622001_2 - 0.53 10.1 0.0 0.53 10.1 0.0 2.3 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family Casein PF00363.16 001303566.1_08523001_1 - 0.016 15.8 6.6 0.024 15.2 5.8 1.8 1 1 0 1 1 1 0 Casein Gp_dh_C PF02800.18 001310173.1_33423001_1 - 2.4e-70 235.0 0.0 3.6e-70 234.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001310173.1_33423001_1 - 1.3e-39 134.4 0.3 3.1e-39 133.3 0.2 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001310173.1_33423001_1 - 0.042 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 7tm_1 PF00001.19 001310199.1_33423001_1 - 1.4e-87 293.2 10.0 1.9e-87 292.8 10.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001310199.1_33423001_1 - 8.2e-18 64.6 23.7 5.4e-14 52.1 15.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.7 001310199.1_33423001_1 - 2.6e-05 23.6 26.0 0.0078 15.5 18.7 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001310199.1_33423001_1 - 0.00014 21.6 11.6 0.00014 21.6 11.6 2.4 2 1 0 2 2 2 1 Olfactory receptor Rifin_STEVOR PF02009.14 001310199.1_33423001_1 - 0.03 14.1 0.8 0.073 12.8 0.8 1.6 1 0 0 1 1 1 0 Rifin/stevor family CcmH PF03918.12 001310199.1_33423001_1 - 0.058 12.5 0.2 0.6 9.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF3806 PF12713.5 001310199.1_33423001_1 - 0.11 12.2 0.9 4.4 7.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3806) DUF2207 PF09972.7 001310199.1_33423001_1 - 0.89 8.1 10.4 16 4.0 0.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF912 PF06024.10 001310199.1_33423001_1 - 1.5 9.1 9.5 2 8.6 0.6 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.4 001310199.1_33423001_1 - 2.2 9.0 4.8 4.9 7.9 0.0 3.4 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Virul_fac_BrkB PF03631.13 001310199.1_33423001_1 - 8.6 5.7 14.8 0.19 11.2 1.3 2.9 3 0 0 3 3 3 0 Virulence factor BrkB IL1 PF00340.17 001310200.1_33422001_1 - 2.1e-42 143.4 0.6 3.7e-42 142.7 0.6 1.4 1 0 0 1 1 1 1 Interleukin-1 / 18 IL1_propep PF02394.14 001310200.1_33422001_1 - 8.3e-40 136.0 0.6 5.7e-38 130.0 0.1 2.4 2 0 0 2 2 2 2 Interleukin-1 propeptide Transferrin PF00405.15 001303567.1_08525001_2 - 2.8e-255 845.0 4.5 1.8e-172 572.8 0.0 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.5 001303567.1_08525001_2 - 1.2e-08 34.7 0.0 0.0029 17.1 0.0 2.6 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein IL12p40_C PF10420.7 001290887.1_07323001_1 - 2.5e-21 75.8 4.8 3e-21 75.6 1.0 2.4 2 0 0 2 2 2 1 Cytokine interleukin-12p40 C-terminus Ig_5 PF16681.3 001290887.1_07323001_1 - 1.3e-06 28.6 2.0 9.4e-06 25.8 0.0 2.8 2 1 1 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.4 001290887.1_07323001_1 - 6.7e-06 26.5 4.5 4.7e-05 23.8 0.1 3.0 3 0 0 3 3 3 1 Immunoglobulin domain fn3 PF00041.19 001290887.1_07323001_1 - 1.8e-05 24.9 0.3 0.00052 20.2 0.3 2.8 2 1 0 2 2 2 1 Fibronectin type III domain Ig_4 PF16680.3 001290887.1_07323001_1 - 2e-05 24.7 1.7 0.00019 21.5 0.0 2.8 2 1 2 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_2 PF13895.4 001290887.1_07323001_1 - 0.00024 21.3 1.4 0.003 17.8 0.0 2.8 2 1 1 3 3 3 1 Immunoglobulin domain I-set PF07679.14 001290887.1_07323001_1 - 0.055 13.4 3.6 0.29 11.1 0.2 3.6 3 2 0 3 3 3 0 Immunoglobulin I-set domain V-set PF07686.15 001290887.1_07323001_1 - 0.31 11.1 4.0 28 4.8 0.0 3.6 3 1 1 4 4 4 0 Immunoglobulin V-set domain Neur_chan_memb PF02932.14 001310197.1_33425001_1 - 8.7e-103 343.4 0.0 1.5e-102 342.5 0.0 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.21 001310197.1_33425001_1 - 2.9e-75 252.3 1.5 3.7e-75 251.9 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.7 001310197.1_33425001_1 - 0.48 9.7 7.1 0.97 8.7 7.1 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Endothelin PF00322.15 001310179.1_33423001_2 - 3.8e-23 80.6 14.8 3.2e-20 71.3 6.4 2.4 2 0 0 2 2 2 2 Endothelin family MHC_I PF00129.16 001303570.1_08524001_1 - 4.1e-44 150.1 0.0 5.8e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001303570.1_08524001_1 - 8.4e-09 35.7 0.1 4.1e-08 33.4 0.0 2.1 3 0 0 3 3 3 1 Immunoglobulin C1-set domain MHC_I_3 PF16497.3 001303570.1_08524001_1 - 0.0084 15.5 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 MHC-I family domain Ig_3 PF13927.4 001303570.1_08524001_1 - 0.075 13.5 0.7 0.36 11.3 0.0 2.4 3 0 0 3 3 3 0 Immunoglobulin domain IL2 PF00715.15 001305898.1_29721001_1 - 2.1e-80 267.6 6.5 2.3e-80 267.5 6.5 1.0 1 0 0 1 1 1 1 Interleukin 2 Plasmid_RAQPRD PF09686.8 001305898.1_29721001_1 - 0.0024 17.9 0.1 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 Plasmid protein of unknown function (Plasmid_RAQPRD) IL13 PF03487.11 001303521.1_08421001_1 - 7.8e-63 210.0 1.6 9e-63 209.8 1.6 1.0 1 0 0 1 1 1 1 Interleukin-13 TNF PF00229.16 001319779.1_08422001_2 - 2.5e-38 130.7 0.0 3.7e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family FKBP_C PF00254.26 001308526.1_02623001_3 - 1.9e-48 162.6 0.0 8e-30 102.9 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.26 001308526.1_02623001_3 - 6.1e-18 63.7 5.6 7.4e-08 31.8 0.8 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.15 001308526.1_02623001_3 - 5.8e-13 47.8 4.7 0.00013 21.6 0.5 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.4 001308526.1_02623001_3 - 1.1e-10 40.7 3.8 6.3e-05 22.8 0.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.4 001308526.1_02623001_3 - 1.6e-08 34.5 0.5 0.057 14.0 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.4 001308526.1_02623001_3 - 8.1e-08 32.5 1.4 0.021 15.2 0.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.4 001308526.1_02623001_3 - 2.3e-06 27.6 0.4 0.00055 20.1 0.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.4 001308526.1_02623001_3 - 5.3e-06 25.9 0.8 0.00019 21.1 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001308526.1_02623001_3 - 4.1e-05 23.4 1.1 0.016 15.1 0.2 2.5 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.4 001308526.1_02623001_3 - 0.00052 19.5 1.6 0.079 12.5 0.0 3.2 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.4 001308526.1_02623001_3 - 0.00057 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.6 001308526.1_02623001_3 - 0.0019 17.1 4.3 0.3 9.8 1.0 2.5 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.4 001308526.1_02623001_3 - 0.0029 18.2 0.1 0.81 10.5 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat PknG_TPR PF16918.3 001308526.1_02623001_3 - 0.0076 14.9 0.1 0.011 14.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_16 PF13432.4 001308526.1_02623001_3 - 0.0094 16.5 0.1 2.4 8.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001308526.1_02623001_3 - 0.0095 16.0 5.4 0.058 13.5 1.6 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.4 001308526.1_02623001_3 - 0.018 14.8 0.3 0.083 12.7 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Casein_kappa PF00997.16 001303560.1_08522001_3 - 9.7e-71 236.9 18.8 1.5e-70 236.3 18.8 1.3 1 0 0 1 1 1 1 Kappa casein Serum_albumin PF00273.18 001323778.1_20925001_1 - 8.7e-155 510.7 44.7 4.3e-60 202.4 10.3 3.0 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.8 001323778.1_20925001_1 - 1.9e-07 30.8 17.2 0.03 14.2 0.2 6.1 5 0 0 5 5 5 3 Vitamin D binding protein, domain III 7tm_1 PF00001.19 001323782.1_20925001_1 - 5.9e-32 110.8 18.0 9.8e-32 110.1 18.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.4 001323782.1_20925001_1 - 1.9e-21 75.4 13.4 6e-07 29.0 0.0 5.3 2 2 3 5 5 5 4 Leucine rich repeat GnHR_trans PF12369.6 001323782.1_20925001_1 - 1.4e-16 60.9 1.4 2.9e-16 59.9 1.4 1.5 1 0 0 1 1 1 1 Gonadotropin hormone receptor transmembrane region LRR_5 PF13306.4 001323782.1_20925001_1 - 3e-14 52.9 0.3 1.9e-07 31.0 0.0 2.4 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.5 001323782.1_20925001_1 - 2.6e-05 24.3 22.4 0.37 11.1 0.2 4.9 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRRNT PF01462.16 001323782.1_20925001_1 - 2.8e-05 23.5 2.5 4.3e-05 22.9 0.5 2.4 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.4 001323782.1_20925001_1 - 0.031 13.6 6.0 0.039 13.3 1.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeat TPR_1 PF00515.26 148465.1_26226120_1 - 2.1e-16 58.8 3.0 1.5e-06 27.6 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.15 148465.1_26226120_1 - 1.2e-13 49.9 0.1 0.00029 20.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.4 148465.1_26226120_1 - 3.9e-12 45.2 0.1 0.00025 20.7 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.4 148465.1_26226120_1 - 6.5e-12 45.5 0.1 2.9e-08 33.7 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.4 148465.1_26226120_1 - 1.3e-09 38.0 7.2 0.43 11.2 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.4 148465.1_26226120_1 - 2e-09 37.7 0.8 0.041 14.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.4 148465.1_26226120_1 - 1.6e-08 34.0 13.3 0.093 12.9 0.0 5.3 6 0 0 6 6 5 4 Tetratricopeptide repeat DUF3808 PF10300.7 148465.1_26226120_1 - 1.5e-06 27.1 0.5 2.9e-06 26.1 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.4 148465.1_26226120_1 - 1.3e-05 25.7 0.0 0.067 13.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.4 148465.1_26226120_1 - 1.5e-05 24.5 0.8 1.5e-05 24.5 0.8 2.3 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_10 PF13374.4 148465.1_26226120_1 - 0.0023 17.6 6.1 2.6 7.9 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat Foie-gras_1 PF11817.6 148465.1_26226120_1 - 0.0081 15.6 1.4 7.5 5.9 0.1 3.2 2 1 1 3 3 3 1 Foie gras liver health family 1 TPR_11 PF13414.4 148465.1_26226120_1 - 0.01 15.3 5.7 0.84 9.2 0.0 3.6 4 0 0 4 4 4 0 TPR repeat RPN7 PF10602.7 148465.1_26226120_1 - 0.011 15.2 4.6 0.087 12.3 0.0 2.9 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_14 PF13428.4 148465.1_26226120_1 - 0.019 15.6 0.0 3 8.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Heme_oxygenase PF01126.18 148465.1_26226120_1 - 0.025 14.2 0.6 0.062 12.9 0.6 1.5 1 0 0 1 1 1 0 Heme oxygenase Fis1_TPR_C PF14853.4 148465.1_26226120_1 - 0.034 14.1 0.9 16 5.5 0.2 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.5 148465.1_26226120_1 - 0.046 13.8 5.6 0.6 10.2 0.3 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.16 148465.1_26226120_1 - 0.13 12.2 4.8 14 5.7 0.0 4.9 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.4 148465.1_26226120_2 - 0.046 14.2 0.0 0.08 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4521 PF15021.4 001358260.1_32923001_2 - 7.7e-96 319.8 5.4 9.4e-96 319.5 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4521) ATP-synt PF00231.17 001310268.1_25623001_1 - 2.6e-78 263.5 4.6 3e-78 263.2 4.6 1.0 1 0 0 1 1 1 1 ATP synthase Pkinase PF00069.23 001009322.1_22424001_3 - 7.1e-65 218.8 0.0 9.1e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001009322.1_22424001_3 - 4e-21 75.3 0.0 5.7e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001009322.1_22424001_3 - 5.7e-09 35.6 0.0 8.1e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001009322.1_22424001_3 - 1.2e-06 27.9 0.0 1.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001009322.1_22424001_3 - 0.04 13.7 0.4 0.073 12.8 0.1 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.9 001009322.1_22424001_3 - 0.21 10.5 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.18 001009322.1_22424001_3 - 0.23 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Spectrin PF00435.19 031675.2_45728001_1 - 4.8e-70 232.6 30.2 4.4e-23 81.6 5.3 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.29 031675.2_45728001_1 - 1.6e-53 179.4 1.1 3.8e-26 91.3 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.8 031675.2_45728001_1 - 1.4e-26 92.2 0.0 3.9e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.30 031675.2_45728001_1 - 1e-09 37.1 0.1 0.0022 17.3 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.4 031675.2_45728001_1 - 2.5e-06 26.8 0.2 0.0038 16.9 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain CAMSAP_CH PF11971.6 031675.2_45728001_1 - 4.6e-06 26.2 0.0 0.00012 21.7 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_7 PF13499.4 031675.2_45728001_1 - 2.4e-05 24.6 0.1 7e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.4 031675.2_45728001_1 - 0.0039 16.8 0.1 0.068 12.8 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair F-box-like PF12937.5 001033156.4_32927001_2 - 5.3e-09 35.7 5.0 6.5e-09 35.4 3.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.31 001033156.4_32927001_2 - 3.3e-08 33.1 0.4 1.3e-07 31.1 0.4 2.1 1 0 0 1 1 1 1 F-box domain SAM_1 PF00536.28 001082164.1_37926001_3 - 9.1e-09 35.5 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.14 001082164.1_37926001_3 - 0.00037 20.3 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.15 001082164.1_37926001_3 - 0.015 15.3 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_60s PF00428.17 001082164.1_37926001_3 - 0.02 15.3 7.5 0.02 15.3 7.5 5.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein PTPRCAP PF15713.3 001082164.1_37926001_3 - 0.23 11.6 7.1 0.41 10.8 7.1 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PBP1_TM PF14812.4 001082164.1_37926001_3 - 0.92 9.8 6.0 3.3 8.1 6.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.4 001082164.1_37926001_3 - 1.4 8.5 3.9 2.6 7.6 3.9 1.3 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.8 001082164.1_37926001_3 - 7.4 6.9 12.9 13 6.2 12.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain F-actin_cap_A PF01267.15 001168692.1_22425001_2 - 6e-106 353.6 1.7 7.2e-106 353.3 1.7 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CAP_N PF01213.17 001168692.1_22425001_2 - 0.18 11.1 0.7 4.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GTP_EFTU PF00009.25 001133289.1_43527001_1 - 6.3e-63 211.7 0.0 9.2e-63 211.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.16 001133289.1_43527001_1 - 7.6e-34 116.0 0.0 2.6e-33 114.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.4 001133289.1_43527001_1 - 4.3e-29 100.3 0.0 8.4e-29 99.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.22 001133289.1_43527001_1 - 1.2e-23 82.9 0.0 3.5e-23 81.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.23 001133289.1_43527001_1 - 2e-16 60.0 0.0 5e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.3 001133289.1_43527001_1 - 3e-06 26.9 0.0 1.7e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.21 001133289.1_43527001_1 - 0.0071 16.3 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.14 001133289.1_43527001_1 - 0.038 13.2 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AvrPtoB_bdg PF16847.3 001133289.1_43527001_1 - 0.085 13.2 0.0 0.46 10.9 0.0 2.2 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain Ribosomal_L5 PF00281.17 001131913.2_43522001_1 - 4.7e-23 81.1 0.0 3.1e-21 75.3 0.0 2.6 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.19 001131913.2_43522001_1 - 1.1e-21 76.7 0.0 2.1e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus DUF4604 PF15377.4 001131913.2_43522001_1 - 0.4 11.0 24.1 0.75 10.1 24.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Med19 PF10278.7 001131913.2_43522001_1 - 3.5 7.4 28.2 4.7 7.0 28.2 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.7 001131913.2_43522001_2 - 0.0031 17.0 27.9 0.0051 16.3 27.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4604 PF15377.4 001131913.2_43522001_2 - 0.14 12.4 20.6 0.21 11.9 20.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RNA_polI_A34 PF08208.9 001131913.2_43522001_2 - 0.66 9.9 25.3 0.79 9.7 25.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Connexin PF00029.17 001134825.1_43522001_1 - 2.3 7.8 15.7 3 7.4 15.7 1.1 1 0 0 1 1 1 0 Connexin TOM_sub5 PF15178.4 001134825.1_43522001_2 - 1.3e-34 117.7 1.3 2.3e-34 117.0 1.3 1.4 1 0 0 1 1 1 1 Mitochondrial import receptor subunit TOM5 homolog Tom5 PF10642.7 001134825.1_43522001_2 - 0.006 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Otopetrin PF03189.11 001134825.1_43522001_2 - 0.011 14.4 1.5 0.014 14.1 1.5 1.1 1 0 0 1 1 1 0 Otopetrin EOS1 PF12326.6 001134825.1_43522001_2 - 0.05 13.4 0.3 0.048 13.5 0.3 1.2 1 0 0 1 1 1 0 N-glycosylation protein Eapp_C PF10238.7 001134825.1_43522001_2 - 0.59 10.1 17.3 1 9.3 17.3 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein 7tm_1 PF00001.19 001134825.1_43522001_3 - 1.6 7.8 7.3 2.1 7.4 7.3 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) FAD_binding_1 PF00667.18 001173002.1_09925001_2 - 4.4e-87 291.2 0.0 6.5e-87 290.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.23 001173002.1_09925001_2 - 9.7e-39 132.7 0.2 4.1e-38 130.7 0.3 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.19 001173002.1_09925001_2 - 1.9e-18 67.0 0.0 5.7e-18 65.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain TUDOR PF00567.22 001133919.2_43528001_3 - 2.4e-85 282.5 6.5 1.1e-32 112.5 0.4 3.7 3 0 0 3 3 3 3 Tudor domain OST-HTH PF12872.5 001133919.2_43528001_3 - 3.3e-19 68.4 0.1 5.5e-10 38.9 0.0 4.7 4 0 0 4 4 4 3 OST-HTH/LOTUS domain Agenet PF05641.10 001133919.2_43528001_3 - 0.00039 20.7 0.3 0.22 11.9 0.1 3.1 2 0 0 2 2 2 2 Agenet domain FAD_binding_1 PF00667.18 001160290.1_37925001_1 - 6.9e-83 277.4 0.0 1e-82 276.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.23 001160290.1_37925001_1 - 5.8e-40 136.7 0.3 2.8e-39 134.5 0.5 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.19 001160290.1_37925001_1 - 6.5e-17 62.0 0.0 2.4e-16 60.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Rad60-SLD PF11976.6 001282258.1_26721001_1 - 7.2e-22 76.9 0.1 8.7e-22 76.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.21 001282258.1_26721001_1 - 1.5e-18 66.2 0.5 1.7e-18 65.9 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.23 001281659.1_31323001_1 - 2.8e-73 246.4 0.0 1.6e-64 217.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.15 001281659.1_31323001_1 - 3.8e-35 121.3 0.0 5.7e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001281659.1_31323001_1 - 0.0066 15.7 0.1 0.6 9.2 0.0 2.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.21 001281659.1_31323001_1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABA_GPCR PF12430.6 001246813.1_14224001_1 - 1.9e-42 145.0 11.5 1.9e-42 145.0 11.5 2.1 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.6 001246813.1_14224001_1 - 1.1e-28 99.0 0.4 2.9e-28 97.6 0.1 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal NPCC PF08058.9 001246813.1_14224001_1 - 0.64 9.9 0.0 0.64 9.9 0.0 3.3 3 0 0 3 3 3 0 Nuclear pore complex component Mito_carr PF00153.25 001284116.1_29524001_2 - 3.5e-70 231.9 0.1 1.3e-23 82.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase_Tyr PF07714.15 001283991.1_29525001_3 - 2.9e-09 36.5 0.2 2e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.23 001283991.1_29525001_3 - 6.9e-05 22.2 0.2 0.00042 19.6 0.1 2.1 1 1 1 2 2 2 1 Protein kinase domain PIP49_C PF12260.6 001283991.1_29525001_3 - 0.083 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 TNF PF00229.16 001305919.1_29722001_2 - 3e-29 101.4 0.1 5.4e-29 100.6 0.1 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family LETM1 PF07766.11 001351313.1_26225001_3 - 4.7e-56 189.9 0.3 5.8e-56 189.6 0.3 1.1 1 0 0 1 1 1 1 LETM1-like protein LSM PF01423.20 001291883.1_21222001_3 - 6.1e-20 70.6 0.1 7.7e-20 70.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Reticulon PF02453.15 135830.1_26224120_1 - 6.9e-47 159.2 6.7 9.1e-47 158.8 6.7 1.2 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.10 135830.1_26224120_1 - 0.1 11.9 4.2 0.025 13.9 1.1 1.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) RHD_DNA_bind PF00554.20 019408.3_32927001_1 - 3.3e-65 219.0 0.0 4.8e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 019408.3_32927001_1 - 4.3e-39 132.6 0.0 7.5e-39 131.8 0.0 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.5 019408.3_32927001_1 - 4.7e-26 91.0 4.1 1.2e-10 41.7 0.2 4.4 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.28 019408.3_32927001_1 - 5.4e-25 86.6 21.1 3.6e-05 23.9 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.4 019408.3_32927001_1 - 1.5e-23 82.4 7.1 2.1e-06 27.8 0.2 5.5 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 019408.3_32927001_1 - 1.1e-21 74.4 7.9 0.00017 21.7 0.1 7.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.4 019408.3_32927001_1 - 5.5e-17 61.8 3.4 2.6e-05 24.5 0.1 5.0 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Death PF00531.20 019408.3_32927001_1 - 6.1e-07 29.4 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Death domain DUF2917 PF11142.6 001290722.1_42223001_2 - 0.019 14.3 0.2 0.041 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Globin PF00042.20 001290722.1_42223001_3 - 3.6e-21 75.7 1.9 5.5e-21 75.1 1.9 1.3 1 0 0 1 1 1 1 Globin Bromodomain PF00439.23 037970.1_32929120_3 - 8.2e-36 121.8 2.5 2e-20 72.5 0.1 2.3 2 0 0 2 2 2 2 Bromodomain BET PF17035.3 037970.1_32929120_3 - 5.5e-28 96.8 0.1 5.5e-28 96.8 0.1 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation AF-4 PF05110.11 037970.1_32929120_3 - 0.00095 17.3 50.5 0.019 13.0 23.1 2.3 2 0 0 2 2 2 2 AF-4 proto-oncoprotein Sigma70_ner PF04546.11 037970.1_32929120_3 - 0.0072 16.1 9.2 0.0072 16.1 9.2 1.8 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF4667 PF15700.3 037970.1_32929120_3 - 0.048 13.6 17.0 0.067 13.2 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) CDK2AP PF09806.7 037970.1_32929120_3 - 1.1 9.1 9.1 6.7 6.6 4.3 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein RRN3 PF05327.9 037970.1_32929120_3 - 1.7 7.0 5.6 3.2 6.1 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.8 037970.1_32929120_3 - 2.9 8.2 12.9 9.1 6.6 12.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C2H2 PF00096.24 001169077.1_40426001_1 - 5.3e-26 89.4 53.8 4.9e-06 26.6 2.8 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001169077.1_40426001_1 - 4.5e-16 58.0 50.3 0.0021 18.6 0.9 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001169077.1_40426001_1 - 9.9e-15 54.1 47.9 2.7e-07 30.6 1.2 7.9 8 0 0 8 8 8 4 Zinc-finger double domain zf-H2C2_5 PF13909.4 001169077.1_40426001_1 - 5.8e-05 22.6 34.4 8.5e-05 22.1 3.9 4.6 5 0 0 5 5 5 2 C2H2-type zinc-finger domain DUF3268 PF11672.6 001169077.1_40426001_1 - 0.00024 21.3 14.4 0.007 16.6 0.8 2.6 2 1 0 2 2 2 2 zinc-finger-containing domain FYVE PF01363.19 001169077.1_40426001_1 - 0.0022 17.9 20.4 0.66 10.0 0.5 5.2 5 0 0 5 5 5 2 FYVE zinc finger Actin_micro PF17003.3 001169077.1_40426001_1 - 0.07 12.2 6.4 2.2 7.2 0.4 3.6 3 1 1 4 4 4 0 Putative actin-like family GAGA PF09237.9 001169077.1_40426001_1 - 0.075 12.7 7.9 1.6 8.5 0.6 3.0 2 1 0 2 2 2 0 GAGA factor zf-C2H2_7 PF15269.4 001169077.1_40426001_1 - 0.21 11.6 17.6 0.34 10.9 0.5 3.8 3 1 0 3 3 3 0 Zinc-finger zf-C2HC_2 PF13913.4 001169077.1_40426001_1 - 6.6 6.6 8.9 6.8 6.6 0.8 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.6 001169077.1_40426001_1 - 8.6 6.7 44.3 0.86 9.9 2.0 6.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Skp1_POZ PF03931.13 001246227.1_22421001_1 - 4.6e-11 42.6 0.0 6.3e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ank_2 PF12796.5 001315716.1_49823001_1 - 5.4e-34 116.5 2.2 9.1e-13 48.5 0.5 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001315716.1_49823001_1 - 3.5e-28 97.1 12.6 4.5e-08 33.1 0.2 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.4 001315716.1_49823001_1 - 7.3e-28 93.4 6.3 1.2e-05 25.1 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.28 001315716.1_49823001_1 - 1.6e-27 94.5 19.5 2.5e-05 24.4 0.1 7.2 6 1 1 7 7 7 6 Ankyrin repeat Ank_4 PF13637.4 001315716.1_49823001_1 - 7.7e-27 93.2 5.4 3e-12 46.7 0.2 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) DER1 PF04511.13 152573.1_32923120_1 - 7.6e-21 74.6 2.7 1e-20 74.2 2.7 1.1 1 0 0 1 1 1 1 Der1-like family DER1 PF04511.13 152573.1_32923120_3 - 7.8e-29 100.6 0.5 1.1e-28 100.2 0.5 1.1 1 0 0 1 1 1 1 Der1-like family MFS_1 PF07690.14 152573.1_32923120_3 - 0.01 14.7 2.8 0.017 13.9 2.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NAD_kinase PF01513.19 001198993.1_26227001_1 - 2.4e-67 227.1 0.0 3.2e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.22 001198993.1_26227001_1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Bcl-2 PF00452.17 001009282.2_22422001_1 - 1.4e-27 96.0 0.1 2.5e-27 95.3 0.1 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family CF222 PF15661.3 001009282.2_22422001_1 - 0.032 13.0 0.0 0.035 12.8 0.0 1.0 1 0 0 1 1 1 0 C6orf222, uncharacterised family V-set PF07686.15 001009296.1_22422001_1 - 3.5e-11 43.1 0.0 5.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001009296.1_22422001_1 - 0.00015 22.2 0.1 0.00095 19.6 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001009296.1_22422001_1 - 0.0094 16.0 0.0 0.036 14.1 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001009296.1_22422001_1 - 0.011 15.7 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.4 001009296.1_22422001_1 - 0.022 14.9 0.0 0.07 13.3 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin domain ig PF00047.23 001105171.1_29624001_2 - 5.7e-34 116.0 0.0 4.5e-12 45.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001105171.1_29624001_2 - 1.4e-20 73.3 0.0 6.4e-08 32.7 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001105171.1_29624001_2 - 3.4e-16 59.5 0.0 0.00025 21.5 0.0 4.0 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001105171.1_29624001_2 - 2.1e-08 34.2 0.2 0.96 9.5 0.0 4.8 3 2 1 4 4 4 3 Immunoglobulin V-set domain AAA_12 PF13087.4 152862.1_32929120_1 - 1.5e-30 106.1 0.0 2.2e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.4 152862.1_32929120_1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Dna2 PF08696.9 152862.1_32929120_2 - 9.3e-61 205.0 0.0 1.5e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.4 152862.1_32929120_2 - 7.1e-35 120.9 0.0 1.4e-18 67.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.4 152862.1_32929120_2 - 1.5e-17 63.7 0.0 3.3e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.4 152862.1_32929120_2 - 9.1e-15 54.7 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.4 152862.1_32929120_2 - 1.5e-09 38.2 0.0 3.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.20 152862.1_32929120_2 - 0.0029 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.16 152862.1_32929120_2 - 0.0053 16.4 1.0 1.7 8.2 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.4 152862.1_32929120_2 - 0.0087 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.21 152862.1_32929120_2 - 0.023 14.6 0.5 0.049 13.5 0.5 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.4 152862.1_32929120_2 - 0.024 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_RecD PF05127.12 152862.1_32929120_2 - 0.034 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Helicase PhoH PF02562.14 152862.1_32929120_2 - 0.038 13.3 0.0 0.077 12.3 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein cobW PF02492.17 152862.1_32929120_2 - 0.04 13.4 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.12 152862.1_32929120_2 - 0.055 13.2 0.1 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF853 PF05872.10 152862.1_32929120_2 - 0.058 11.8 0.0 0.083 11.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Cas_Cas4 PF01930.15 152862.1_32929120_2 - 0.06 13.3 1.7 0.78 9.7 1.5 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF83 AAA_16 PF13191.4 152862.1_32929120_2 - 0.061 13.6 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.27 152862.1_32929120_2 - 0.074 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.19 152862.1_32929120_2 - 0.093 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_18 PF13238.4 152862.1_32929120_2 - 0.1 13.0 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Vac_Fusion PF02346.14 152862.1_32929120_2 - 0.12 11.9 0.2 0.56 9.7 0.2 2.1 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 AAA_23 PF13476.4 152862.1_32929120_2 - 0.12 12.7 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Auts2 PF15336.4 010183.1_32926001_2 - 2.7e-69 233.5 6.6 2.7e-69 233.5 6.6 2.2 2 0 0 2 2 2 1 Autism susceptibility gene 2 protein ADH_N_2 PF16884.3 214385.1_49823001_2 - 2.3e-38 130.3 0.0 4.2e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.24 214385.1_49823001_2 - 2.9e-23 82.1 0.0 4.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.4 214385.1_49823001_2 - 7.5e-09 36.6 0.0 1.9e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HDNR PF15115.4 001077085.2_06522001_3 - 9.3e-20 71.4 0.2 1.2e-19 71.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function with conserved HDNR motif zf-RING_UBOX PF13445.4 001112632.1_40423001_1 - 5.7e-13 48.5 6.1 6.4e-13 48.4 3.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger SPRY PF00622.26 001112632.1_40423001_1 - 9.3e-11 41.8 0.3 2.2e-10 40.6 0.3 1.6 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_4 PF15227.4 001112632.1_40423001_1 - 9.7e-11 41.5 8.8 9.7e-11 41.5 8.8 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.23 001112632.1_40423001_1 - 8.3e-10 38.2 8.2 2.1e-09 36.9 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001112632.1_40423001_1 - 2.3e-08 33.6 8.7 9.9e-08 31.6 8.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001112632.1_40423001_1 - 6.7e-08 32.5 8.0 6.7e-08 32.5 8.0 2.0 2 0 0 2 2 1 1 Ring finger domain zf-B_box PF00643.22 001112632.1_40423001_1 - 7.6e-08 32.3 3.6 7.6e-08 32.3 3.6 3.0 3 1 0 3 3 2 1 B-box zinc finger zf-C3HC4_3 PF13920.4 001112632.1_40423001_1 - 1.3e-07 31.2 6.1 1.3e-07 31.2 6.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001112632.1_40423001_1 - 2e-07 30.7 6.2 2e-07 30.7 6.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.13 001112632.1_40423001_1 - 2.7e-05 24.1 0.0 6.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 U-box domain TMF_TATA_bd PF12325.6 001112632.1_40423001_1 - 0.00052 20.1 1.6 0.00052 20.1 1.6 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding zf-RING_10 PF16685.3 001112632.1_40423001_1 - 0.021 14.8 4.3 0.021 14.8 4.3 2.0 2 0 0 2 2 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.4 001112632.1_40423001_1 - 0.021 14.6 9.5 0.021 14.6 9.5 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-Nse PF11789.6 001112632.1_40423001_1 - 0.025 14.3 4.8 0.066 12.9 4.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.9 001112632.1_40423001_1 - 0.068 13.0 3.8 0.051 13.4 1.4 2.1 2 0 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.4 001112632.1_40423001_1 - 0.079 12.7 4.7 0.12 12.2 3.4 2.0 2 1 0 2 2 1 0 zf-RING of BARD1-type protein AAA_11 PF13086.4 001112632.1_40423001_1 - 0.34 10.5 4.8 0.5 9.9 4.8 1.2 1 0 0 1 1 1 0 AAA domain zf-RING_11 PF17123.3 001112632.1_40423001_1 - 0.4 10.3 4.8 1.6 8.4 4.8 2.2 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.4 001112632.1_40423001_1 - 0.49 10.4 4.0 0.52 10.3 1.1 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.4 001112632.1_40423001_1 - 0.69 9.6 8.3 5.7 6.6 8.6 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.5 001112632.1_40423001_1 - 1.2 9.3 10.6 0.53 10.5 6.7 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain LsmAD PF06741.11 001112632.1_40423001_1 - 1.6 9.2 4.6 1.1 9.8 2.4 1.9 1 1 0 1 1 1 0 LsmAD domain DUF4407 PF14362.4 001112632.1_40423001_1 - 3.2 6.9 6.3 4.6 6.4 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CBS PF00571.26 013010.2_45724001_2 - 9.1e-35 118.8 2.4 9.3e-10 38.7 0.4 4.3 4 0 0 4 4 4 4 CBS domain DRTGG PF07085.10 013010.2_45724001_2 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 DRTGG domain Actin PF00022.17 001101682.2_37923001_2 - 1.4e-149 498.0 0.0 4.3e-149 496.4 0.0 1.6 1 1 0 1 1 1 1 Actin SNARE_assoc PF09335.9 001329394.1_26229001_1 - 6.5e-08 32.9 0.0 1.7e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein Hormone_recep PF00104.28 001308519.1_02626001_1 - 5.3e-30 104.4 6.8 8.7e-30 103.7 6.8 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001308519.1_02626001_1 - 1.4e-28 99.0 12.8 2.8e-28 98.1 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CAP_N PF01213.17 001308519.1_02626001_1 - 4.1 6.7 6.2 8.5 5.6 6.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal E1-E2_ATPase PF00122.18 001114532.2_21027001_1 - 7.2e-58 195.4 2.1 7.2e-58 195.4 2.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.19 001114532.2_21027001_1 - 5.6e-44 149.9 0.3 5.6e-44 149.9 0.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.4 001114532.2_21027001_1 - 1.2e-23 82.9 0.0 2.6e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.24 001114532.2_21027001_1 - 7.6e-19 68.7 0.1 1.2e-09 38.6 0.0 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 001114532.2_21027001_1 - 3.8e-18 64.8 0.0 7e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.10 001114532.2_21027001_1 - 7.2e-06 25.8 1.1 0.00081 19.1 0.5 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase GDA1_CD39 PF01150.15 001281951.1_31324001_2 - 3.9e-76 256.3 0.0 1.4e-75 254.5 0.0 1.8 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4703 PF15775.3 001271236.1_45723001_3 - 9.9e-76 253.6 8.7 1.2e-75 253.3 8.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4703) GCR PF02155.13 001308533.1_02625001_1 - 1.3e-181 603.5 13.3 1.7e-181 603.1 13.3 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor Hormone_recep PF00104.28 001308533.1_02625001_1 - 2.4e-30 105.6 4.7 2.4e-30 105.6 4.7 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001308533.1_02625001_1 - 2.8e-28 98.0 13.0 5.2e-28 97.2 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001279987.1_46726001_1 - 5e-30 104.5 6.8 8.7e-30 103.7 6.8 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001279987.1_46726001_1 - 1.4e-28 99.0 12.8 2.8e-28 98.1 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) IL6 PF00489.15 001310169.1_33422001_2 - 5.2e-84 280.3 0.7 6e-84 280.1 0.7 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family GCSF PF16647.3 001310169.1_33422001_2 - 0.0046 16.7 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Granulocyte colony-stimulating factor PAS_11 PF14598.4 001301675.1_34024001_1 - 3.1e-26 91.6 0.2 2.5e-22 79.0 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 001301675.1_34024001_1 - 5.5e-21 74.6 0.0 2.5e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.10 001301675.1_34024001_1 - 5.2e-20 71.4 0.0 7.2e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.24 001301675.1_34024001_1 - 1.7e-17 63.0 0.8 3.3e-17 62.0 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001301675.1_34024001_1 - 1e-08 35.2 0.0 4.6e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001301675.1_34024001_1 - 2.5e-05 24.4 0.0 0.009 16.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.9 001301675.1_34024001_1 - 0.022 15.3 0.0 0.087 13.4 0.0 1.9 2 0 0 2 2 2 0 PAS fold PAS_11 PF14598.4 001330100.1_34026001_1 - 2.4e-23 82.3 1.2 1.5e-20 73.2 0.0 3.9 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.10 001330100.1_34026001_1 - 6.2e-18 64.7 1.5 9e-16 57.8 0.1 2.8 3 0 0 3 3 3 2 PAS fold HLH PF00010.24 001330100.1_34026001_1 - 1.3e-09 37.7 0.6 3.6e-09 36.3 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.23 001330100.1_34026001_1 - 2.2e-09 37.2 3.3 1.9e-07 30.9 0.0 3.8 4 0 0 4 4 4 1 PAS fold PAS_9 PF13426.5 001330100.1_34026001_1 - 0.00027 21.0 0.0 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain Hormone_1 PF00103.18 001304934.1_01322001_1 - 2.2e-80 269.3 0.2 2.5e-80 269.1 0.2 1.0 1 0 0 1 1 1 1 Somatotropin hormone family KIAA1430 PF13879.4 001304934.1_01322001_1 - 0.018 15.6 0.2 0.44 11.2 0.0 2.2 2 0 0 2 2 2 0 KIAA1430 homologue zf-RING_2 PF13639.4 001100739.1_45726001_3 - 9.6e-11 41.6 8.4 2.4e-10 40.4 8.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 001100739.1_45726001_3 - 8.2e-09 35.5 6.0 2.2e-08 34.1 6.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001100739.1_45726001_3 - 1.3e-07 31.3 7.5 2.8e-07 30.2 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001100739.1_45726001_3 - 4.8e-07 29.4 7.2 1e-06 28.3 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001100739.1_45726001_3 - 9.3e-06 25.4 4.3 2.5e-05 24.1 4.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 001100739.1_45726001_3 - 3.1e-05 23.6 5.5 6.6e-05 22.5 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.3 001100739.1_45726001_3 - 6.1e-05 22.4 3.8 0.00014 21.3 3.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.4 001100739.1_45726001_3 - 0.00022 21.0 6.9 0.0005 19.9 6.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.3 001100739.1_45726001_3 - 0.00023 20.7 3.4 0.00023 20.7 3.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.4 001100739.1_45726001_3 - 0.00096 18.8 4.5 0.0018 18.0 4.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.6 001100739.1_45726001_3 - 0.026 14.6 1.4 0.068 13.2 1.4 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.5 001100739.1_45726001_3 - 0.046 13.6 6.4 0.25 11.3 6.4 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.9 001100739.1_45726001_3 - 0.066 13.4 7.2 0.14 12.4 7.2 1.6 1 0 0 1 1 1 0 RING-like domain Zf_RING PF16744.3 001100739.1_45726001_3 - 0.11 12.5 3.1 0.25 11.4 3.1 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3H2C3 PF17122.3 001100739.1_45726001_3 - 0.27 11.2 4.1 0.74 9.8 4.1 1.8 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.5 001100739.1_45726001_3 - 1.1 9.3 7.1 2.6 8.1 7.1 1.6 1 0 0 1 1 1 0 RING-variant domain UPF0193 PF05250.9 132765.1_06524120_2 - 7.6e-59 199.0 1.2 1.3e-58 198.2 1.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) UPF0193 PF05250.9 132765.1_06524120_3 - 1.6e-23 83.5 1.7 3.3e-23 82.5 1.7 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) Bromodomain PF00439.23 151733.1_32929120_2 - 6.9e-24 83.6 0.6 1e-23 83.0 0.6 1.3 1 0 0 1 1 1 1 Bromodomain PCAF_N PF06466.9 151733.1_32929120_3 - 5.5e-110 366.7 1.1 7.5e-110 366.3 1.1 1.2 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Acetyltransf_1 PF00583.23 151733.1_32929120_3 - 1e-09 38.5 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.5 151733.1_32929120_3 - 8.5e-07 28.8 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 151733.1_32929120_3 - 2e-05 24.8 0.2 3.8e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Yip1 PF04893.15 038062.1_32924120_3 - 2.3e-19 69.6 8.7 3.1e-19 69.2 8.2 1.4 1 1 0 1 1 1 1 Yip1 domain DUF2070 PF09843.7 038062.1_32924120_3 - 0.43 8.7 4.3 0.58 8.2 4.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_M10 PF00413.22 001081847.2_21024001_3 - 4.7e-62 208.4 0.0 8.6e-62 207.5 0.0 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.17 001081847.2_21024001_3 - 8.2e-44 147.2 23.7 2e-16 59.5 0.3 4.9 5 0 0 5 5 5 4 Hemopexin PG_binding_1 PF01471.16 001081847.2_21024001_3 - 1.8e-14 53.5 0.6 5.2e-14 52.1 0.1 2.1 3 0 0 3 3 3 1 Putative peptidoglycan binding domain Astacin PF01400.22 001081847.2_21024001_3 - 0.0066 16.0 0.0 4.4 6.7 0.0 2.6 3 0 0 3 3 3 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.4 001081847.2_21024001_3 - 0.018 15.4 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.4 001081847.2_21024001_3 - 0.031 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.4 001081847.2_21024001_3 - 0.043 13.8 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.3 001081847.2_21024001_3 - 0.059 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Met-zincin RCC1 PF00415.16 148015.1_26229120_1 - 5.9e-54 180.4 25.6 2.7e-14 53.4 2.1 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 148015.1_26229120_1 - 6.9e-28 95.7 26.1 8.8e-10 38.0 2.5 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.29 148015.1_26229120_3 - 6.9e-20 71.2 2.1 4.7e-19 68.5 0.1 2.7 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.13 148015.1_26229120_3 - 4.2e-05 23.5 1.5 0.012 15.6 0.1 3.0 2 1 0 2 2 2 2 BTB And C-terminal Kelch Microcephalin PF12258.6 136159.1_26228120_1 - 3.9e-169 562.9 21.1 3.9e-169 562.9 21.1 1.6 2 0 0 2 2 2 1 Microcephalin protein PTCB-BRCT PF12738.5 136159.1_26228120_2 - 1.3e-17 63.3 1.3 2.2e-17 62.6 1.3 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.24 136159.1_26228120_2 - 2.4e-05 24.6 0.2 4.5e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.3 136159.1_26228120_2 - 0.00076 19.7 0.1 0.0015 18.7 0.1 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.3 136159.1_26228120_2 - 0.04 14.1 0.4 0.068 13.3 0.4 1.3 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain CD4-extracel PF09191.8 001308980.1_47125001_1 - 6.3e-35 119.7 0.3 2.4e-34 117.8 0.2 2.1 2 0 0 2 2 2 1 CD4, extracellular ig PF00047.23 001308980.1_47125001_1 - 2.4e-18 65.9 1.2 7.7e-14 51.5 0.0 5.2 4 1 0 4 4 4 1 Immunoglobulin domain Tcell_CD4_C PF12104.6 001308980.1_47125001_1 - 5.5e-14 51.6 3.7 1.4e-13 50.4 3.7 1.6 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region Ig_3 PF13927.4 001308980.1_47125001_1 - 1e-13 51.5 0.7 1.7e-07 31.6 0.0 4.4 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.15 001308980.1_47125001_1 - 1.1e-12 48.0 0.2 9.9e-11 41.6 0.0 3.6 3 1 2 5 5 5 1 Immunoglobulin V-set domain I-set PF07679.14 001308980.1_47125001_1 - 1.1e-10 41.3 0.2 1.9e-08 34.1 0.0 3.6 4 0 0 4 4 4 1 Immunoglobulin I-set domain C2-set PF05790.13 001308980.1_47125001_1 - 1.5e-10 41.0 2.3 0.0013 18.8 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin C2-set domain Ig_2 PF13895.4 001308980.1_47125001_1 - 1.8e-10 40.9 1.3 1.5e-05 25.1 0.0 4.8 3 1 1 4 4 4 1 Immunoglobulin domain Receptor_2B4 PF11465.6 001308980.1_47125001_1 - 0.0012 18.9 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.3 001308980.1_47125001_1 - 0.021 14.7 0.0 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF1049 PF06305.9 001308980.1_47125001_1 - 0.1 12.3 0.3 0.21 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Homeobox PF00046.27 001289868.1_37424001_2 - 1.9e-20 72.3 7.9 3.6e-20 71.4 7.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.27 001289852.1_37425001_1 - 2.6e-20 71.8 7.9 4.8e-20 71.0 7.9 1.4 1 0 0 1 1 1 1 Homeobox domain DUF3915 PF13054.4 001289852.1_37425001_2 - 6.4 6.7 5.5 4 7.3 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) RGM_C PF06534.11 001283308.1_29527001_1 - 2.2e-70 235.5 0.0 3.4e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.10 001283308.1_29527001_1 - 1.6e-68 230.0 2.0 1.6e-68 230.0 2.0 1.6 2 0 0 2 2 2 1 Repulsive guidance molecule (RGM) N-terminus Pkinase PF00069.23 020341.3_26229001_3 - 1.1e-66 224.8 0.0 1.4e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 020341.3_26229001_3 - 1.6e-43 148.7 0.0 2.4e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.26 020341.3_26229001_3 - 3.2e-16 59.3 0.1 7.6e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.4 020341.3_26229001_3 - 3.9e-07 29.6 0.0 6.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MHC_I PF00129.16 001280855.1_47123001_1 - 3.9e-77 257.7 2.4 5.4e-77 257.3 2.4 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001280855.1_47123001_1 - 4e-16 59.1 0.0 1.1e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001280855.1_47123001_1 - 3.8e-14 52.2 4.6 3.8e-14 52.2 4.6 1.9 2 0 0 2 2 2 1 MHC_I C-terminus Ig_3 PF13927.4 001280855.1_47123001_1 - 6.9e-06 26.5 1.3 4.3e-05 23.9 0.0 2.7 2 1 1 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.4 001280855.1_47123001_1 - 0.00012 22.2 0.0 0.0004 20.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001280855.1_47123001_1 - 0.00028 20.8 0.1 0.0017 18.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain MHC_I_3 PF16497.3 001280855.1_47123001_1 - 0.00029 20.2 0.1 0.00051 19.4 0.0 1.5 1 1 0 1 1 1 1 MHC-I family domain C2-set_2 PF08205.10 001280855.1_47123001_1 - 0.012 15.5 0.7 0.026 14.4 0.1 1.9 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain I-set PF07679.14 001280855.1_47123001_1 - 0.12 12.4 0.2 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin I-set domain MHC_I PF00129.16 001308992.1_47123001_1 - 3.2e-51 173.3 1.3 4.1e-51 173.0 1.3 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001308992.1_47123001_1 - 1.4e-14 54.2 0.0 2.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_3 PF16497.3 001308992.1_47123001_1 - 4.5e-10 39.2 0.3 6.9e-10 38.6 0.3 1.3 1 0 0 1 1 1 1 MHC-I family domain Ig_2 PF13895.4 001308992.1_47123001_1 - 0.00051 20.2 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001308992.1_47123001_1 - 0.0019 18.7 0.0 0.0038 17.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001308992.1_47123001_1 - 0.0027 17.7 0.1 0.0064 16.5 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain Rep_N PF08724.8 001308992.1_47123001_1 - 0.028 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Rep protein catalytic domain like SKG6 PF08693.8 001308992.1_47123001_1 - 0.31 10.3 1.6 0.51 9.6 1.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ODC_AZ PF02100.15 001290301.1_47122001_1 - 5.1e-15 55.4 0.0 7.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290317.1_39422001_2 - 6.5e-15 55.0 0.0 9.6e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF846 PF05832.10 001281858.1_39422001_2 - 1.2e-55 187.2 8.7 1.6e-55 186.8 8.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMC PF07810.11 001281858.1_39422001_2 - 0.061 13.8 3.0 0.12 12.9 2.9 1.7 1 1 0 1 1 1 0 TMC domain TMEM192 PF14802.4 001281858.1_39422001_2 - 0.081 11.9 0.2 0.14 11.1 0.2 1.3 1 0 0 1 1 1 0 TMEM192 family HXXEE PF13787.4 001281858.1_39422001_2 - 0.6 10.8 6.9 2.7 8.7 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif DUF2207 PF09972.7 001281858.1_39422001_2 - 2.2 6.8 5.3 2.5 6.6 0.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Ald_Xan_dh_C2 PF02738.16 001308454.1_39429001_2 - 1.5e-185 617.7 0.0 1.8e-185 617.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001308454.1_39429001_2 - 6e-44 149.6 0.0 1.5e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001308454.1_39429001_2 - 3.9e-31 107.5 0.0 7.6e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001308454.1_39429001_2 - 1e-30 105.3 0.7 2.6e-30 104.1 0.7 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001308454.1_39429001_2 - 1.5e-28 98.8 0.0 4.6e-28 97.3 0.0 1.9 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001308454.1_39429001_2 - 6.2e-09 35.6 3.4 2.3e-08 33.7 0.1 3.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Asp_protease_2 PF13650.4 001291038.1_39426001_1 - 0.00042 20.8 0.0 0.00067 20.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291038.1_39426001_1 - 0.0035 17.2 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291038.1_39426001_1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291038.1_39426001_2 - 2.9e-16 59.4 1.7 1.4e-15 57.3 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291038.1_39426001_2 - 2.1e-15 56.4 0.0 3.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291038.1_39426001_2 - 0.00031 20.5 2.9 0.00053 19.8 2.9 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291038.1_39426001_2 - 0.00037 20.0 0.2 0.00088 18.8 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291038.1_39426001_2 - 0.003 17.3 0.2 0.0053 16.5 0.2 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 zf-CCHC PF00098.21 001291038.1_39426001_2 - 0.03 14.3 2.2 0.12 12.3 2.2 2.2 1 0 0 1 1 1 0 Zinc knuckle bZIP_1 PF00170.19 001291038.1_39426001_2 - 0.07 13.1 5.4 0.067 13.2 1.8 2.1 1 1 1 2 2 2 0 bZIP transcription factor V_ATPase_I PF01496.17 001291038.1_39426001_2 - 0.086 10.6 0.6 0.12 10.1 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rootletin PF15035.4 001291038.1_39426001_2 - 0.088 12.7 6.5 0.17 11.8 6.5 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion eIF3g PF12353.6 001291038.1_39426001_2 - 0.091 13.0 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G SlyX PF04102.10 001291038.1_39426001_2 - 0.095 13.2 2.9 0.39 11.2 2.9 2.1 1 0 0 1 1 1 0 SlyX Uso1_p115_C PF04871.11 001291038.1_39426001_2 - 0.11 12.7 2.4 0.2 11.9 2.4 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.6 001291038.1_39426001_2 - 0.16 11.1 2.3 0.3 10.2 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.10 001291038.1_39426001_2 - 0.17 12.2 8.9 0.48 10.8 8.9 1.7 1 0 0 1 1 1 0 Cell division protein ZapB IncA PF04156.12 001291038.1_39426001_2 - 0.25 11.0 3.3 0.56 9.8 3.3 1.5 1 0 0 1 1 1 0 IncA protein SHE3 PF17078.3 001291038.1_39426001_2 - 0.52 9.8 6.7 0.33 10.5 4.5 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 GIT_CC PF16559.3 001291038.1_39426001_2 - 0.55 10.2 6.6 4.8 7.2 6.6 2.2 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.10 001291038.1_39426001_2 - 0.62 10.4 5.1 1.5 9.1 5.1 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001291038.1_39426001_2 - 0.71 10.4 4.7 0.52 10.8 2.5 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001291038.1_39426001_2 - 1.1 7.9 5.1 1.8 7.2 5.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.11 001291038.1_39426001_2 - 1.9 8.1 5.3 4.1 7.0 5.3 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TSC22 PF01166.16 001291038.1_39426001_2 - 2.3 8.5 6.3 13 6.0 6.3 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family HALZ PF02183.16 001291038.1_39426001_2 - 2.4 8.3 4.8 1.5 9.0 1.0 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper XhlA PF10779.7 001291038.1_39426001_2 - 5.4 7.2 5.2 10 6.3 5.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_2 PF07716.13 001291038.1_39426001_2 - 6.8 6.7 16.8 0.19 11.7 3.0 3.5 2 1 1 3 3 3 0 Basic region leucine zipper DivIC PF04977.13 001291038.1_39426001_2 - 7.9 6.2 9.7 1.3 8.7 5.7 1.7 2 0 0 2 2 1 0 Septum formation initiator RNase_H PF00075.22 001285809.1_39422001_2 - 6.9e-46 155.9 0.0 9.7e-46 155.4 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285809.1_39422001_2 - 2.1e-19 69.4 0.9 4.7e-19 68.3 0.9 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285809.1_39422001_2 - 0.0006 19.4 0.0 0.0021 17.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase-like Orn_Arg_deC_N PF02784.14 001293717.1_39425001_3 - 1.9e-71 240.3 0.0 2.4e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293717.1_39425001_3 - 1.2e-18 67.1 0.0 2.4e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293717.1_39425001_3 - 7.8e-05 22.1 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ODC_AZ PF02100.15 001289715.1_39423001_3 - 2.2e-20 72.6 0.0 3.9e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Orn_Arg_deC_N PF02784.14 001291492.1_39429001_1 - 8.1e-64 215.3 0.1 1e-63 214.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291492.1_39429001_1 - 1e-24 86.6 0.0 1.9e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ODC_AZ PF02100.15 001289994.1_39424001_1 - 6.4e-20 71.1 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Orn_Arg_deC_N PF02784.14 001301729.1_39429001_2 - 7.9e-64 215.3 0.1 9.9e-64 215.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301729.1_39429001_2 - 1e-24 86.6 0.0 1.8e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 7tm_2 PF00002.22 126014.1_45725120_2 - 2.7e-36 125.0 1.0 3.5e-36 124.6 1.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.20 126014.1_45725120_3 - 2.6e-16 59.5 1.1 4.8e-16 58.7 1.1 1.5 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.22 126014.1_45725120_3 - 1e-15 57.6 2.4 1.4e-15 57.1 2.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ald_Xan_dh_C2 PF02738.16 001282155.1_47129001_1 - 2.6e-188 626.8 0.0 3.4e-188 626.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001282155.1_47129001_1 - 9e-47 158.8 0.0 2e-46 157.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001282155.1_47129001_1 - 4.6e-36 123.4 0.2 1.5e-35 121.7 0.2 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001282155.1_47129001_1 - 8.7e-31 106.0 0.0 3.9e-30 103.9 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.18 001282155.1_47129001_1 - 3e-30 103.8 0.5 8.4e-30 102.4 0.5 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.25 001282155.1_47129001_1 - 1.4e-09 37.6 0.1 1.4e-09 37.6 0.1 3.0 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain UQ_con PF00179.24 038137.1_06522120_3 - 1.4e-34 118.6 0.1 2.2e-34 117.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF544 PF04424.11 133858.4_32926001_2 - 2.3e-38 130.7 0.0 3.8e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF371 PF04027.11 133858.4_32926001_2 - 0.034 14.0 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF371) ANF_receptor PF01094.26 000908.3_26229001_2 - 1.3e-50 172.4 0.0 1.6e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Orn_Arg_deC_N PF02784.14 001301744.1_16227001_1 - 2.7e-63 213.6 0.1 3.4e-63 213.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301744.1_16227001_1 - 8e-24 83.7 0.0 1.5e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291518.1_16227001_3 - 2.9e-63 213.5 0.1 3.7e-63 213.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291518.1_16227001_3 - 8.5e-24 83.7 0.0 1.6e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain IL2 PF00715.15 001281314.1_16221001_1 - 4.8e-72 240.5 6.9 5.5e-72 240.3 6.9 1.0 1 0 0 1 1 1 1 Interleukin 2 Desmo_N PF06771.9 001281314.1_16221001_1 - 0.032 14.4 0.4 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus RNase_H PF00075.22 001285475.1_16224001_2 - 2.3e-43 147.7 0.0 3.5e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285475.1_16224001_2 - 4.9e-19 68.2 0.5 9.3e-19 67.3 0.5 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285475.1_16224001_2 - 0.0059 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like TNF PF00229.16 001281316.1_16222001_1 - 4.3e-35 120.3 0.0 5.7e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family AAA PF00004.27 001293084.1_16223001_1 - 5.3e-43 146.5 0.0 1.2e-42 145.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293084.1_16223001_1 - 2.2e-07 31.0 0.0 5.5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293084.1_16223001_1 - 2.9e-06 27.2 0.0 1.6e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293084.1_16223001_1 - 4e-06 27.2 0.2 7.5e-05 23.0 0.0 2.7 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293084.1_16223001_1 - 2.4e-05 24.5 1.4 0.0053 16.9 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293084.1_16223001_1 - 9.6e-05 21.6 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293084.1_16223001_1 - 0.0015 17.4 0.0 0.0032 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293084.1_16223001_1 - 0.0017 18.0 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293084.1_16223001_1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293084.1_16223001_1 - 0.0024 18.3 0.2 0.02 15.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.9 001293084.1_16223001_1 - 0.0063 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.19 001293084.1_16223001_1 - 0.0064 15.8 0.1 0.016 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.14 001293084.1_16223001_1 - 0.0073 15.7 0.1 0.13 11.5 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein ATPase PF06745.11 001293084.1_16223001_1 - 0.0082 15.4 0.0 0.024 13.9 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.4 001293084.1_16223001_1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293084.1_16223001_1 - 0.023 14.8 3.4 0.052 13.6 3.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293084.1_16223001_1 - 0.024 14.2 0.1 0.1 12.2 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293084.1_16223001_1 - 0.027 14.1 0.0 0.076 12.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain TsaE PF02367.15 001293084.1_16223001_1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293084.1_16223001_1 - 0.048 12.6 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.4 001293084.1_16223001_1 - 0.051 13.0 0.0 0.17 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.4 001293084.1_16223001_1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.11 001293084.1_16223001_1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.20 001293084.1_16223001_1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.4 001293084.1_16223001_1 - 0.073 12.6 0.4 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.4 001293084.1_16223001_1 - 0.079 13.2 0.5 0.47 10.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.10 001293084.1_16223001_1 - 0.12 11.5 0.2 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.4 001293084.1_16223001_1 - 0.13 12.5 0.2 0.43 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain Laminin_II PF06009.10 001293084.1_16223001_1 - 0.18 11.7 3.4 1.2 9.0 0.9 2.7 3 0 0 3 3 3 0 Laminin Domain II DivIC PF04977.13 001293084.1_16223001_1 - 0.41 10.3 3.4 1 9.1 3.4 1.6 1 0 0 1 1 1 0 Septum formation initiator MscS_porin PF12795.5 001293084.1_16223001_1 - 4.1 6.8 11.6 6.4 6.1 11.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain RNase_H PF00075.22 001286025.1_29223001_2 - 2.9e-44 150.6 0.0 4.3e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001286025.1_29223001_2 - 6.9e-19 67.8 0.6 1.4e-18 66.8 0.6 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001286025.1_29223001_2 - 0.00038 20.0 0.0 0.00093 18.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase-like Ald_Xan_dh_C2 PF02738.16 001303259.1_29229001_1 - 2.1e-187 623.8 0.0 2.9e-187 623.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001303259.1_29229001_1 - 1.3e-39 135.5 0.3 3.6e-39 134.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.15 001303259.1_29229001_1 - 6.5e-32 109.6 0.4 3.3e-27 94.5 0.0 3.7 4 0 0 4 4 4 2 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.20 001303259.1_29229001_1 - 9.1e-30 103.1 0.3 1.8e-29 102.2 0.3 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001303259.1_29229001_1 - 5.5e-29 99.8 0.2 1.6e-28 98.3 0.2 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.25 001303259.1_29229001_1 - 9.2e-05 22.2 1.0 0.00022 21.0 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain 7tm_1 PF00001.19 001280862.1_29223001_3 - 3.9e-37 127.8 13.2 5.3e-37 127.4 13.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.7 001280862.1_29223001_3 - 9e-05 21.4 16.7 0.019 13.8 5.2 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt Cytochrom_B_N_2 PF13631.4 001280862.1_29223001_3 - 0.00022 21.1 0.8 0.00094 19.1 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB 7TM_GPCR_Srv PF10323.7 001280862.1_29223001_3 - 0.00042 19.6 8.4 0.00067 19.0 8.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.7 001280862.1_29223001_3 - 0.0008 18.7 8.0 0.0017 17.6 8.0 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.7 001280862.1_29223001_3 - 0.0011 18.3 6.2 0.13 11.5 2.3 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF846 PF05832.10 001281878.1_29222001_1 - 6.2e-56 188.2 10.0 7.9e-56 187.8 10.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM192 PF14802.4 001281878.1_29222001_1 - 0.045 12.7 0.3 0.08 11.9 0.3 1.4 1 0 0 1 1 1 0 TMEM192 family HXXEE PF13787.4 001281878.1_29222001_1 - 0.67 10.6 8.1 1.9e+02 2.7 8.1 2.1 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif Promethin PF16015.3 001281878.1_29222001_1 - 2.7 7.8 14.2 0.15 11.9 2.7 2.2 2 0 0 2 2 2 0 Promethin Globin PF00042.20 001280882.1_29221001_3 - 1e-30 106.4 0.3 7.6e-30 103.6 0.0 1.9 2 0 0 2 2 2 1 Globin Orn_Arg_deC_N PF02784.14 001301776.1_29229001_3 - 5.1e-62 209.4 0.1 6.5e-62 209.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301776.1_29229001_3 - 8.7e-25 86.8 0.0 1.6e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Globin PF00042.20 001280884.1_29222001_3 - 2.7e-27 95.4 0.2 4.1e-27 94.8 0.2 1.3 1 0 0 1 1 1 1 Globin Orn_Arg_deC_N PF02784.14 001291479.1_29229001_1 - 5.3e-62 209.3 0.1 6.8e-62 209.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291479.1_29229001_1 - 9.1e-25 86.8 0.0 1.7e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ephrin PF00812.15 001305196.1_44923001_1 - 1.8e-51 173.6 0.3 1.6e-50 170.6 0.1 2.0 2 0 0 2 2 2 1 Ephrin TMEM132D_C PF15706.3 001305196.1_44923001_1 - 0.002 17.7 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM154 PF15102.4 001305196.1_44923001_1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF4381 PF14316.4 001305196.1_44923001_1 - 0.043 13.9 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.4 001305196.1_44923001_1 - 0.083 13.6 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.3 001305196.1_44923001_1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator CDI PF02234.17 001305195.1_44922001_1 - 5.6e-21 74.4 2.6 9.4e-21 73.6 2.6 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor V1R PF03402.12 001360013.1_26122001_1 - 4.6e-25 88.6 10.4 6.3e-25 88.2 10.4 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001360013.1_26122001_1 - 2.2e-09 36.7 10.4 2.8e-09 36.4 10.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001360013.1_26122001_1 - 1e-05 24.8 15.1 1.9e-05 23.9 15.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Asp_protease_2 PF13650.4 001291140.1_48829001_2 - 0.00031 21.2 0.0 0.00051 20.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291140.1_48829001_2 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291140.1_48829001_2 - 0.033 14.6 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291140.1_48829001_3 - 1.3e-15 57.3 5.4 3.1e-15 56.1 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291140.1_48829001_3 - 5.9e-15 55.0 0.0 2e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) ATG16 PF08614.9 001291140.1_48829001_3 - 2.2e-05 24.6 0.8 3.7e-05 23.9 0.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Rootletin PF15035.4 001291140.1_48829001_3 - 8.5e-05 22.6 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291140.1_48829001_3 - 0.0002 21.2 5.1 0.00033 20.4 5.1 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291140.1_48829001_3 - 0.0011 18.5 0.2 0.0034 16.9 0.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger SR-25 PF10500.7 001291140.1_48829001_3 - 0.0088 15.5 10.4 0.018 14.5 10.4 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3450 PF11932.6 001291140.1_48829001_3 - 0.016 14.4 4.9 0.028 13.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uso1_p115_C PF04871.11 001291140.1_48829001_3 - 0.045 14.0 4.0 0.077 13.2 4.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF5082 PF16888.3 001291140.1_48829001_3 - 0.057 13.6 4.6 0.28 11.4 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF737 PF05300.9 001291140.1_48829001_3 - 0.062 13.5 4.1 0.11 12.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CENP-H PF05837.10 001291140.1_48829001_3 - 0.063 13.6 3.5 0.14 12.5 3.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.10 001291140.1_48829001_3 - 0.094 13.0 8.6 0.21 11.9 8.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB IncA PF04156.12 001291140.1_48829001_3 - 0.11 12.2 10.9 0.21 11.2 10.9 1.4 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.10 001291140.1_48829001_3 - 0.14 12.0 1.8 0.28 11.1 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-CCHC PF00098.21 001291140.1_48829001_3 - 0.16 12.0 7.1 0.24 11.4 2.2 3.1 2 0 0 2 2 2 0 Zinc knuckle DUF972 PF06156.11 001291140.1_48829001_3 - 0.17 12.4 4.0 0.43 11.1 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.10 001291140.1_48829001_3 - 0.17 11.1 3.1 0.28 10.4 3.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.9 001291140.1_48829001_3 - 0.41 9.3 5.3 0.75 8.5 5.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.10 001291140.1_48829001_3 - 0.64 8.0 6.3 0.92 7.4 6.3 1.1 1 0 0 1 1 1 0 HOOK protein TMF_DNA_bd PF12329.6 001291140.1_48829001_3 - 0.8 9.6 8.2 1.6 8.7 8.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.10 001291140.1_48829001_3 - 0.82 10.2 5.4 2.3 8.8 5.4 1.7 1 0 0 1 1 1 0 SlyX bZIP_1 PF00170.19 001291140.1_48829001_3 - 0.83 9.7 8.1 2 8.5 4.0 2.2 1 1 0 1 1 1 0 bZIP transcription factor FlxA PF14282.4 001291140.1_48829001_3 - 0.86 9.5 13.8 2.5 8.0 13.8 1.7 1 1 0 1 1 1 0 FlxA-like protein APG6 PF04111.10 001291140.1_48829001_3 - 1.9 7.7 6.0 3.6 6.7 6.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.16 001291140.1_48829001_3 - 2.1 8.5 8.6 8 6.6 2.2 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper SHE3 PF17078.3 001291140.1_48829001_3 - 2.3 7.8 8.5 0.91 9.1 6.0 1.5 2 0 0 2 2 1 0 SWI5-dependent HO expression protein 3 Mnd1 PF03962.13 001291140.1_48829001_3 - 2.7 7.7 5.9 5.7 6.6 5.9 1.4 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.13 001291140.1_48829001_3 - 4.1 7.1 11.2 15 5.3 0.9 2.5 1 1 1 2 2 2 0 Septum formation initiator GIT_CC PF16559.3 001291140.1_48829001_3 - 5 7.1 10.2 21 5.1 9.8 2.1 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Asp_protease_2 PF13650.4 001291373.1_42229001_2 - 0.00036 21.0 0.0 0.00059 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291373.1_42229001_2 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291373.1_42229001_2 - 0.058 13.8 0.0 0.097 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291373.1_42229001_3 - 7.7e-15 54.8 3.4 1.2e-14 54.3 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291373.1_42229001_3 - 1.7e-14 53.5 0.0 3.1e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291373.1_42229001_3 - 0.0016 18.2 5.8 0.0026 17.5 5.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291373.1_42229001_3 - 0.0019 17.7 0.2 0.0049 16.4 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291373.1_42229001_3 - 0.054 13.4 7.9 0.098 12.6 7.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CCDC106 PF15794.3 001291373.1_42229001_3 - 0.085 12.4 1.4 0.2 11.2 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 IncA PF04156.12 001291373.1_42229001_3 - 0.26 10.9 4.3 0.49 10.0 4.3 1.3 1 0 0 1 1 1 0 IncA protein TolA_bind_tri PF16331.3 001291373.1_42229001_3 - 0.37 10.8 4.3 0.7 9.9 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation SHE3 PF17078.3 001291373.1_42229001_3 - 0.43 10.1 6.9 0.82 9.2 6.9 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CENP-H PF05837.10 001291373.1_42229001_3 - 0.43 10.9 3.7 0.84 9.9 3.7 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.9 001291373.1_42229001_3 - 0.56 8.9 6.0 0.95 8.1 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.19 001291373.1_42229001_3 - 0.67 10.0 8.2 2.3 8.3 8.2 1.9 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.11 001291373.1_42229001_3 - 0.75 10.3 4.7 1.7 9.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291373.1_42229001_3 - 0.89 9.9 10.4 2 8.8 10.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.13 001291373.1_42229001_3 - 1.6 8.4 5.9 4.2 7.1 5.9 1.6 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291373.1_42229001_3 - 1.8 8.5 7.1 4.7 7.2 7.1 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291373.1_42229001_3 - 2.4 8.7 5.8 5.7 7.5 5.8 1.6 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291373.1_42229001_3 - 3 6.9 5.3 5 6.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Retrotrans_gag PF03732.15 001291110.1_36527001_1 - 7.1e-16 58.1 2.7 5.1e-15 55.4 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291110.1_36527001_1 - 3e-15 55.9 0.0 5.6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291110.1_36527001_1 - 3.3e-05 23.9 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291110.1_36527001_1 - 0.00025 20.8 4.3 0.00044 20.0 4.3 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291110.1_36527001_1 - 0.0011 18.5 0.2 0.0024 17.4 0.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CASP_C PF08172.10 001291110.1_36527001_1 - 0.0011 18.2 0.1 0.0018 17.5 0.1 1.2 1 0 0 1 1 1 1 CASP C terminal SR-25 PF10500.7 001291110.1_36527001_1 - 0.0074 15.8 6.4 0.0074 15.8 6.4 2.8 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein CENP-H PF05837.10 001291110.1_36527001_1 - 0.049 13.9 4.3 0.13 12.5 4.3 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-CCHC PF00098.21 001291110.1_36527001_1 - 0.053 13.5 2.2 0.17 11.9 2.2 2.0 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_C PF04871.11 001291110.1_36527001_1 - 0.066 13.4 3.8 0.11 12.8 3.8 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SHE3 PF17078.3 001291110.1_36527001_1 - 0.073 12.6 5.3 0.048 13.2 3.4 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ZapB PF06005.10 001291110.1_36527001_1 - 0.082 13.2 8.3 0.22 11.9 8.3 1.6 1 0 0 1 1 1 0 Cell division protein ZapB eIF3g PF12353.6 001291110.1_36527001_1 - 0.11 12.8 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Spc7 PF08317.9 001291110.1_36527001_1 - 0.11 11.2 4.4 0.22 10.2 4.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291110.1_36527001_1 - 0.13 12.7 3.4 0.39 11.2 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.17 001291110.1_36527001_1 - 0.14 9.9 0.4 0.2 9.3 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.10 001291110.1_36527001_1 - 0.15 12.0 0.6 0.3 10.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.6 001291110.1_36527001_1 - 0.16 11.9 5.5 0.33 10.8 5.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TolA_bind_tri PF16331.3 001291110.1_36527001_1 - 0.22 11.5 4.9 0.48 10.4 4.9 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation IncA PF04156.12 001291110.1_36527001_1 - 0.34 10.5 8.0 0.65 9.6 8.0 1.4 1 0 0 1 1 1 0 IncA protein Prominin PF05478.9 001291110.1_36527001_1 - 0.36 8.6 1.0 0.56 8.0 1.0 1.1 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.6 001291110.1_36527001_1 - 0.48 9.5 5.4 0.83 8.8 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.10 001291110.1_36527001_1 - 0.8 10.2 5.2 2.6 8.6 5.2 1.8 1 0 0 1 1 1 0 SlyX GIT_CC PF16559.3 001291110.1_36527001_1 - 1.9 8.4 8.3 5.7 6.9 8.3 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.4 001291110.1_36527001_1 - 3.6 7.5 10.0 12 5.9 9.9 1.7 1 1 0 1 1 1 0 FlxA-like protein TSC22 PF01166.16 001291110.1_36527001_1 - 8 6.7 7.5 43 4.4 7.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family APG6 PF04111.10 001291110.1_36527001_1 - 10 5.3 7.3 2.2 7.4 4.0 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Asp_protease_2 PF13650.4 001291110.1_36527001_3 - 0.0002 21.8 0.0 0.00034 21.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291110.1_36527001_3 - 0.0049 16.7 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291110.1_36527001_3 - 0.022 15.2 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001291375.1_05129001_2 - 0.00029 21.3 0.0 0.00058 20.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291375.1_05129001_2 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291375.1_05129001_2 - 0.05 14.0 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291375.1_05129001_3 - 6.5e-15 55.1 3.4 1.1e-14 54.3 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291375.1_05129001_3 - 1.7e-14 53.5 0.0 3.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291375.1_05129001_3 - 0.0015 18.3 5.8 0.0026 17.5 5.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291375.1_05129001_3 - 0.002 17.7 0.2 0.0049 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291375.1_05129001_3 - 0.056 13.4 7.9 0.097 12.6 7.9 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion zf-CCHC PF00098.21 001291375.1_05129001_3 - 0.078 13.0 2.2 0.35 10.9 2.2 2.3 1 0 0 1 1 1 0 Zinc knuckle CCDC106 PF15794.3 001291375.1_05129001_3 - 0.086 12.4 1.4 0.2 11.2 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 IncA PF04156.12 001291375.1_05129001_3 - 0.29 10.7 4.5 0.55 9.9 4.5 1.3 1 0 0 1 1 1 0 IncA protein TolA_bind_tri PF16331.3 001291375.1_05129001_3 - 0.38 10.7 4.3 0.7 9.9 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation CENP-H PF05837.10 001291375.1_05129001_3 - 0.4 11.0 3.7 0.84 9.9 3.7 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SHE3 PF17078.3 001291375.1_05129001_3 - 0.42 10.2 6.9 0.82 9.2 6.9 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.9 001291375.1_05129001_3 - 0.55 8.9 6.0 0.95 8.1 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291375.1_05129001_3 - 0.76 10.3 4.7 1.7 9.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291375.1_05129001_3 - 0.76 10.1 10.4 2 8.8 10.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.19 001291375.1_05129001_3 - 0.78 9.8 8.2 2.2 8.3 8.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.13 001291375.1_05129001_3 - 1.5 8.5 5.9 4.2 7.1 5.9 1.7 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291375.1_05129001_3 - 2 8.4 7.1 4.7 7.2 7.1 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291375.1_05129001_3 - 2.4 8.7 5.8 5.7 7.5 5.8 1.6 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291375.1_05129001_3 - 3.1 6.9 5.3 5 6.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.6 001291375.1_05129001_3 - 3.3 7.6 8.2 6.4 6.7 8.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Asp_protease_2 PF13650.4 001291181.1_27029001_1 - 0.0093 16.5 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291181.1_27029001_1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.15 001291181.1_27029001_2 - 3e-16 59.3 0.1 3e-16 59.3 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291181.1_27029001_2 - 4.2e-15 55.5 0.0 7.4e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001291181.1_27029001_2 - 0.0016 18.0 0.2 0.004 16.7 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001291181.1_27029001_2 - 0.0024 17.6 3.5 0.004 16.9 3.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH IncA PF04156.12 001291181.1_27029001_2 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 IncA protein Spc29 PF17082.3 001291181.1_27029001_2 - 0.048 13.4 0.2 0.081 12.6 0.2 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 TolA_bind_tri PF16331.3 001291181.1_27029001_2 - 0.095 12.7 2.6 0.19 11.7 2.6 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Rootletin PF15035.4 001291181.1_27029001_2 - 0.1 12.5 7.1 0.2 11.6 7.1 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ERM PF00769.17 001291181.1_27029001_2 - 0.14 11.8 4.6 0.25 11.0 4.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ZapB PF06005.10 001291181.1_27029001_2 - 0.15 12.4 8.0 0.32 11.3 8.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291181.1_27029001_2 - 0.48 11.0 3.0 1.4 9.5 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) SlyX PF04102.10 001291181.1_27029001_2 - 0.51 10.9 4.7 1.4 9.4 4.7 1.7 1 0 0 1 1 1 0 SlyX CCDC106 PF15794.3 001291181.1_27029001_2 - 0.52 9.9 2.3 0.9 9.1 2.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 bZIP_1 PF00170.19 001291181.1_27029001_2 - 1.1 9.3 6.5 2.5 8.2 6.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor zf-CCHC PF00098.21 001291181.1_27029001_2 - 1.3 9.0 7.1 0.31 11.1 2.2 2.5 2 0 0 2 2 2 0 Zinc knuckle GIT_CC PF16559.3 001291181.1_27029001_2 - 2.4 8.1 6.2 8.4 6.4 6.2 1.9 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291181.1_27029001_2 - 4.2 7.6 5.9 11 6.3 5.6 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family CENP-H PF05837.10 001291181.1_27029001_2 - 7.3 6.9 9.9 0.35 11.2 4.1 1.7 2 0 0 2 2 1 0 Centromere protein H (CENP-H) DUF4939 PF16297.3 001291194.1_20328001_1 - 6.8e-15 54.8 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291194.1_20328001_1 - 8.2e-14 51.5 2.7 1.9e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein KASH_CCD PF14662.4 001291194.1_20328001_1 - 0.01 15.5 6.2 0.017 14.8 6.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.10 001291194.1_20328001_1 - 0.019 15.3 8.2 0.046 14.0 8.2 1.6 1 0 0 1 1 1 0 Cell division protein ZapB CCDC106 PF15794.3 001291194.1_20328001_1 - 0.03 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Rootletin PF15035.4 001291194.1_20328001_1 - 0.038 13.9 6.2 0.07 13.1 6.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.10 001291194.1_20328001_1 - 0.048 13.5 0.5 0.097 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.11 001291194.1_20328001_1 - 0.093 13.2 3.8 0.24 11.9 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.19 001291194.1_20328001_1 - 0.11 12.5 6.9 0.33 11.0 6.9 1.8 1 0 0 1 1 1 0 bZIP transcription factor Dynactin_p22 PF07426.9 001291194.1_20328001_1 - 0.14 11.9 2.4 0.27 11.0 2.4 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 Spc7 PF08317.9 001291194.1_20328001_1 - 0.15 10.7 2.4 0.28 9.9 2.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF737 PF05300.9 001291194.1_20328001_1 - 0.2 11.9 3.1 0.42 10.8 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF737) SlyX PF04102.10 001291194.1_20328001_1 - 0.43 11.1 2.9 1.6 9.2 2.9 2.0 1 0 0 1 1 1 0 SlyX DUF3138 PF11336.6 001291194.1_20328001_1 - 0.6 8.5 1.8 0.89 8.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) IncA PF04156.12 001291194.1_20328001_1 - 0.68 9.6 4.2 1.2 8.7 4.2 1.3 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.6 001291194.1_20328001_1 - 0.94 8.6 3.6 1.6 7.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.13 001291194.1_20328001_1 - 4.1 7.1 10.1 0.35 10.6 5.4 1.6 2 0 0 2 2 1 0 Septum formation initiator GIT_CC PF16559.3 001291194.1_20328001_1 - 4.4 7.3 7.6 11 6.1 7.6 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291194.1_20328001_1 - 4.6 7.5 9.3 51 4.2 9.3 2.2 1 1 0 1 1 1 0 TSC-22/dip/bun family Asp_protease_2 PF13650.4 001291194.1_20328001_3 - 0.00021 21.8 0.0 0.00037 21.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.4 001291194.1_20328001_3 - 0.023 15.1 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.9 001291194.1_20328001_3 - 0.041 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4939 PF16297.3 001291361.1_20626001_1 - 3.3e-14 52.6 0.0 6.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291361.1_20626001_1 - 1.3e-13 50.9 2.5 1.5e-13 50.7 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.4 001291361.1_20626001_1 - 0.00062 19.3 0.2 0.0015 18.1 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.21 001291361.1_20626001_1 - 0.046 13.7 2.2 0.13 12.2 2.2 1.9 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.6 001291361.1_20626001_1 - 0.14 12.4 0.1 0.14 12.4 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Asp-B-Hydro_N PF05279.9 001291361.1_20626001_1 - 0.59 10.0 11.2 0.95 9.3 11.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2052 PF09747.7 001291361.1_20626001_1 - 1.3 9.0 10.5 2.3 8.2 10.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC27 PF09507.8 001291361.1_20626001_1 - 3.7 6.7 15.7 6.1 6.0 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp_protease_2 PF13650.4 001291361.1_20626001_3 - 0.0053 17.3 0.0 0.0091 16.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291361.1_20626001_3 - 0.017 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291361.1_20626001_3 - 0.14 12.6 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291342.1_28326001_1 - 3e-16 59.4 2.2 4.1e-15 55.7 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291342.1_28326001_1 - 2.4e-15 56.2 0.0 4.5e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291342.1_28326001_1 - 2.6e-05 24.3 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291342.1_28326001_1 - 0.0002 21.2 4.3 0.00036 20.3 4.3 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291342.1_28326001_1 - 0.00078 19.0 0.2 0.002 17.7 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CASP_C PF08172.10 001291342.1_28326001_1 - 0.00094 18.5 0.1 0.0015 17.8 0.1 1.2 1 0 0 1 1 1 1 CASP C terminal SR-25 PF10500.7 001291342.1_28326001_1 - 0.006 16.1 6.4 0.006 16.1 6.4 2.3 3 0 0 3 3 2 1 Nuclear RNA-splicing-associated protein CENP-H PF05837.10 001291342.1_28326001_1 - 0.036 14.3 4.3 0.11 12.8 4.3 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-CCHC PF00098.21 001291342.1_28326001_1 - 0.049 13.6 2.2 0.14 12.1 2.2 1.9 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_C PF04871.11 001291342.1_28326001_1 - 0.053 13.7 3.8 0.088 13.0 3.8 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF972 PF06156.11 001291342.1_28326001_1 - 0.059 13.9 2.7 0.19 12.2 2.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291342.1_28326001_1 - 0.06 13.7 8.3 0.18 12.1 8.3 1.7 1 0 0 1 1 1 0 Cell division protein ZapB eIF3g PF12353.6 001291342.1_28326001_1 - 0.083 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G SHE3 PF17078.3 001291342.1_28326001_1 - 0.088 12.4 6.0 0.039 13.5 3.4 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.9 001291342.1_28326001_1 - 0.089 11.5 4.4 0.18 10.5 4.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.10 001291342.1_28326001_1 - 0.11 12.4 0.6 0.25 11.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.17 001291342.1_28326001_1 - 0.12 10.1 0.4 0.16 9.7 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.6 001291342.1_28326001_1 - 0.13 12.1 5.5 0.27 11.1 5.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TolA_bind_tri PF16331.3 001291342.1_28326001_1 - 0.16 12.0 4.9 0.4 10.7 4.9 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation IncA PF04156.12 001291342.1_28326001_1 - 0.27 10.9 8.0 0.53 9.9 8.0 1.4 1 0 0 1 1 1 0 IncA protein Prominin PF05478.9 001291342.1_28326001_1 - 0.3 8.9 1.0 0.46 8.2 1.0 1.2 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.6 001291342.1_28326001_1 - 0.38 9.9 5.4 0.68 9.0 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.10 001291342.1_28326001_1 - 0.61 10.6 5.3 2.2 8.8 5.3 1.9 1 0 0 1 1 1 0 SlyX RasGAP_C PF03836.13 001291342.1_28326001_1 - 1.7 8.6 5.6 4.9 7.2 2.5 3.0 4 0 0 4 4 4 0 RasGAP C-terminus GIT_CC PF16559.3 001291342.1_28326001_1 - 1.8 8.5 8.6 5.9 6.9 8.6 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.4 001291342.1_28326001_1 - 2.1 8.3 9.8 7.7 6.4 9.8 1.9 1 1 0 1 1 1 0 FlxA-like protein RCDG1 PF15725.3 001291342.1_28326001_1 - 2.7 8.3 11.6 7.9 6.9 11.6 1.8 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein TSC22 PF01166.16 001291342.1_28326001_1 - 5.1 7.4 7.4 32 4.8 7.4 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family HALZ PF02183.16 001291342.1_28326001_1 - 5.3 7.2 5.7 12 6.1 3.8 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper APG6 PF04111.10 001291342.1_28326001_1 - 6.1 6.0 7.0 1.8 7.7 4.0 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 XhlA PF10779.7 001291342.1_28326001_1 - 9.9 6.3 6.2 19 5.4 6.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Asp_protease_2 PF13650.4 001291342.1_28326001_3 - 0.00017 22.1 0.0 0.00028 21.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291342.1_28326001_3 - 0.0041 17.0 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291342.1_28326001_3 - 0.018 15.5 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease NUDIX_5 PF16705.3 001350674.1_26229001_1 - 6.9e-85 283.1 0.0 1e-84 282.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX, or N-terminal NPxY motif-rich, region of KRIT FERM_M PF00373.16 001350674.1_26229001_1 - 2.6e-19 69.6 0.1 6.2e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 FERM central domain Ank_2 PF12796.5 001350674.1_26229001_1 - 1.5e-15 57.4 0.0 2.3e-06 28.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001350674.1_26229001_1 - 9.6e-13 48.0 0.1 1.3e-08 34.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.4 001350674.1_26229001_1 - 1.8e-10 41.0 0.7 3.1e-07 30.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.28 001350674.1_26229001_1 - 5.4e-09 36.0 0.0 0.073 13.4 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.4 001350674.1_26229001_1 - 8.5e-05 22.5 0.1 0.23 12.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Fes1 PF08609.8 022464.4_26224001_2 - 0.00039 21.1 6.5 0.00048 20.8 2.0 2.5 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 RTTN_N PF14726.4 022464.4_26224001_2 - 0.0081 16.8 1.5 2.2 9.1 0.2 2.7 2 0 0 2 2 2 2 Rotatin, an armadillo repeat protein, centriole functioning DUF4704 PF15787.3 022464.4_26224001_2 - 0.015 14.4 0.8 0.015 14.4 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) HEAT PF02985.20 022464.4_26224001_2 - 0.066 13.4 0.3 2.1 8.7 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat TRAP_beta PF05753.12 001309328.1_21023001_2 - 9.3e-70 233.5 0.0 1.3e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) zf-C4 PF00105.16 001081851.1_21025001_3 - 1.8e-31 108.3 11.5 3.9e-31 107.2 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001081851.1_21025001_3 - 1e-24 87.2 6.3 2.3e-24 86.0 6.3 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SBP56 PF05694.9 001309514.1_21024001_2 - 2.5e-222 738.5 0.0 3e-222 738.2 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.7 001309514.1_21024001_2 - 0.036 13.2 0.0 0.087 11.9 0.0 1.6 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Pkinase PF00069.23 001143800.2_21025001_3 - 4e-56 190.2 0.1 7.2e-56 189.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001143800.2_21025001_3 - 4.7e-36 124.3 0.0 8.2e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase dsrm PF00035.24 001143800.2_21025001_3 - 1.6e-25 89.4 2.8 3.2e-13 50.0 0.0 3.4 3 0 0 3 3 3 2 Double-stranded RNA binding motif Kdo PF06293.12 001143800.2_21025001_3 - 0.036 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DND1_DSRM PF14709.5 001143800.2_21025001_3 - 0.056 13.6 0.0 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 ABC1 PF03109.14 001143800.2_21025001_3 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 ABC1 family IL8 PF00048.18 001081931.2_21022001_1 - 2.2e-21 75.6 2.2 3.8e-21 74.9 2.2 1.4 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Lectin_C PF00059.19 001081812.2_21022001_2 - 8.4e-20 71.4 0.0 1.2e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.16 001081812.2_21022001_2 - 1.7e-10 40.4 36.1 5.2e-05 22.8 18.9 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Arf PF00025.19 001309322.1_21022001_2 - 5e-77 257.2 0.0 6.2e-77 256.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.11 001309322.1_21022001_2 - 4.1e-14 52.7 0.0 5.8e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 001309322.1_21022001_2 - 2.6e-13 49.8 0.0 3.2e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.18 001309322.1_21022001_2 - 2.6e-10 39.9 0.5 2.1e-06 27.0 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.8 001309322.1_21022001_2 - 3.8e-10 39.3 0.0 4.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001309322.1_21022001_2 - 2.4e-09 36.8 0.0 3.1e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001309322.1_21022001_2 - 8.6e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001309322.1_21022001_2 - 0.0025 17.2 0.1 0.015 14.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.14 001309322.1_21022001_2 - 0.008 15.0 0.3 0.18 10.6 0.0 2.3 2 1 0 2 2 2 1 ArgK protein ABC_tran PF00005.25 001309322.1_21022001_2 - 0.025 15.0 0.1 0.48 10.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.4 001309322.1_21022001_2 - 0.043 14.2 0.0 0.06 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.16 001309322.1_21022001_2 - 0.086 12.2 0.5 0.41 10.0 0.5 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.14 001309322.1_21022001_2 - 0.13 12.0 0.1 16 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 bZIP_2 PF07716.13 001278933.1_21023001_2 - 0.13 12.2 1.1 0.3 11.1 1.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper MHC_I PF00129.16 001278933.1_21023001_3 - 3.9e-92 306.6 0.4 5.1e-92 306.2 0.4 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001278933.1_21023001_3 - 3.1e-17 62.7 0.0 6.7e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001278933.1_21023001_3 - 2.8e-11 43.0 5.6 5e-11 42.2 5.6 1.4 1 0 0 1 1 1 1 MHC_I C-terminus C2-set_2 PF08205.10 001278933.1_21023001_3 - 3.6e-05 23.6 0.5 8.4e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.4 001278933.1_21023001_3 - 0.00025 21.5 1.7 0.0038 17.7 0.1 2.7 2 1 1 3 3 3 2 Immunoglobulin domain ig PF00047.23 001278933.1_21023001_3 - 0.0033 17.4 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.4 001278933.1_21023001_3 - 0.0066 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ribosomal_S7e PF01251.16 001286001.1_09922001_3 - 1.3e-93 311.8 3.8 1.5e-93 311.6 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ABC_membrane PF00664.21 001278770.1_09928001_1 - 1.7e-170 565.6 24.6 1.4e-93 313.4 5.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001278770.1_09928001_1 - 9.4e-77 256.0 1.5 2.3e-38 131.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.17 001278770.1_09928001_1 - 1.1e-15 57.5 5.8 4.7e-07 29.3 1.4 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.4 001278770.1_09928001_1 - 1.3e-11 45.1 1.2 0.00018 21.8 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.7 001278770.1_09928001_1 - 4.6e-09 35.4 1.0 0.0006 18.6 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class G-alpha PF00503.18 001278770.1_09928001_1 - 2.5e-08 33.4 0.2 0.0032 16.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF258 PF03193.14 001278770.1_09928001_1 - 9.2e-08 32.0 0.2 0.0055 16.5 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.4 001278770.1_09928001_1 - 9.7e-08 32.3 3.5 0.0095 16.1 0.1 3.4 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.10 001278770.1_09928001_1 - 1.2e-07 31.1 1.2 0.00077 18.7 0.0 3.4 4 0 0 4 4 4 2 Zeta toxin Rad17 PF03215.13 001278770.1_09928001_1 - 3e-06 26.3 0.0 0.033 13.0 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_5 PF07728.12 001278770.1_09928001_1 - 3.5e-06 26.9 0.5 0.049 13.5 0.0 3.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.4 001278770.1_09928001_1 - 1.2e-05 24.8 2.0 0.056 13.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.27 001278770.1_09928001_1 - 2.7e-05 24.4 4.7 0.26 11.6 0.2 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.4 001278770.1_09928001_1 - 3e-05 23.7 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.4 001278770.1_09928001_1 - 0.00011 22.3 2.7 0.28 11.3 0.2 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.4 001278770.1_09928001_1 - 0.00013 22.2 1.2 1.5 8.9 0.1 3.5 2 2 1 3 3 3 2 AAA domain AAA_30 PF13604.4 001278770.1_09928001_1 - 0.00014 21.5 2.9 0.13 11.8 0.2 3.0 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.15 001278770.1_09928001_1 - 0.00018 21.5 1.8 0.7 9.7 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_21 PF13304.4 001278770.1_09928001_1 - 0.00069 19.4 0.1 14 5.2 0.0 4.2 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.11 001278770.1_09928001_1 - 0.00086 18.4 0.1 0.51 9.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) PRK PF00485.16 001278770.1_09928001_1 - 0.0011 18.6 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.18 001278770.1_09928001_1 - 0.0017 18.2 0.3 0.26 11.0 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase ATP-synt_ab PF00006.23 001278770.1_09928001_1 - 0.0022 17.6 1.5 1.8 8.0 0.0 3.1 2 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.20 001278770.1_09928001_1 - 0.0023 18.2 0.0 3.7 7.8 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.4 001278770.1_09928001_1 - 0.0037 16.9 0.1 1.5 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.4 001278770.1_09928001_1 - 0.0056 17.1 0.0 3.3 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.4 001278770.1_09928001_1 - 0.011 15.8 0.0 7.1 6.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.15 001278770.1_09928001_1 - 0.011 15.3 1.6 27 4.3 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein tRNA_lig_kinase PF08303.9 001278770.1_09928001_1 - 0.021 14.8 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain NACHT PF05729.10 001278770.1_09928001_1 - 0.025 14.4 0.3 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.19 001278770.1_09928001_1 - 0.029 13.6 0.0 7.5 5.7 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AIG1 PF04548.14 001278770.1_09928001_1 - 0.057 12.6 0.1 12 5.0 0.1 2.5 2 0 0 2 2 2 0 AIG1 family AAA_25 PF13481.4 001278770.1_09928001_1 - 0.058 12.8 0.1 11 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Peptidase_M23 PF01551.20 001278770.1_09928001_1 - 0.1 12.7 0.3 28 4.9 0.0 3.2 3 0 0 3 3 2 0 Peptidase family M23 MMR_HSR1 PF01926.21 001278770.1_09928001_1 - 0.11 12.5 0.1 9.8 6.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dala_Dala_lig_N PF01820.19 001278770.1_09928001_1 - 0.16 12.0 0.4 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus PduV-EutP PF10662.7 001278770.1_09928001_1 - 0.17 11.5 0.7 15 5.2 0.1 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.13 001278770.1_09928001_1 - 0.26 11.0 3.2 0.71 9.6 0.2 2.7 3 0 0 3 3 3 0 NTPase RNase_H PF00075.22 001286014.1_36322001_1 - 6e-44 149.6 0.0 8.2e-44 149.1 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001286014.1_36322001_1 - 5.9e-20 71.2 2.1 1.1e-19 70.3 2.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001286014.1_36322001_1 - 0.0056 16.2 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase-like LRR_9 PF14580.4 001282029.1_36322001_1 - 3e-13 49.5 0.0 1.3e-12 47.5 0.0 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.5 001282029.1_36322001_1 - 1.7e-07 31.2 6.5 0.00022 21.4 0.1 3.3 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001282029.1_36322001_1 - 1.9e-07 30.6 1.4 1.9e-07 30.6 1.4 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.31 001282029.1_36322001_1 - 0.33 11.5 5.7 91 4.0 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat Calc_CGRP_IAPP PF00214.17 001280872.1_36322001_3 - 4e-15 56.1 4.1 5.4e-14 52.4 0.5 2.1 1 1 1 2 2 2 2 Calcitonin / CGRP / IAPP family ODC_AZ PF02100.15 001289827.1_36323001_1 - 4.9e-20 71.5 0.0 8.2e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290036.1_36324001_2 - 4.2e-20 71.7 0.0 8.2e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Neur_chan_LBD PF02931.21 001323272.1_36324001_1 - 2.1e-73 246.2 1.4 2.7e-73 245.9 1.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001323272.1_36324001_1 - 1.1e-61 208.9 0.0 1.6e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TcpE PF12648.5 001323272.1_36324001_1 - 2.3 8.7 4.8 0.41 11.1 0.7 1.8 2 0 0 2 2 2 0 TcpE family Asp_protease_2 PF13650.4 001291164.1_36329001_1 - 0.016 15.8 0.0 0.026 15.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.15 001291164.1_36329001_2 - 9.6e-15 54.5 1.5 2.7e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291164.1_36329001_2 - 4.1e-14 52.3 0.0 7.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291164.1_36329001_2 - 0.0011 18.8 3.7 0.0017 18.1 3.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291164.1_36329001_2 - 0.0015 18.1 0.2 0.0044 16.6 0.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291164.1_36329001_2 - 0.025 14.3 0.1 0.038 13.7 0.1 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Rootletin PF15035.4 001291164.1_36329001_2 - 0.049 13.6 5.3 0.086 12.8 5.3 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2505 PF10698.7 001291164.1_36329001_2 - 0.063 13.3 0.5 0.11 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) ZapB PF06005.10 001291164.1_36329001_2 - 0.14 12.5 8.5 0.31 11.4 8.5 1.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.19 001291164.1_36329001_2 - 0.2 11.7 3.9 0.52 10.3 3.9 1.7 1 0 0 1 1 1 0 bZIP transcription factor CCDC106 PF15794.3 001291164.1_36329001_2 - 0.22 11.1 1.8 0.36 10.4 1.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001291164.1_36329001_2 - 0.35 11.2 3.1 0.78 10.0 3.1 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001291164.1_36329001_2 - 0.54 10.8 2.4 1.2 9.6 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TolA_bind_tri PF16331.3 001291164.1_36329001_2 - 0.59 10.1 4.0 1.1 9.2 4.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation SlyX PF04102.10 001291164.1_36329001_2 - 0.7 10.4 3.6 1.7 9.2 3.6 1.6 1 0 0 1 1 1 0 SlyX zf-CCHC PF00098.21 001291164.1_36329001_2 - 0.95 9.5 6.7 0.34 10.9 2.2 2.7 2 0 0 2 2 2 0 Zinc knuckle GIT_CC PF16559.3 001291164.1_36329001_2 - 3 7.8 6.5 8.9 6.3 6.5 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.13 001291164.1_36329001_2 - 7.4 6.3 7.0 15 5.3 7.0 1.5 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.16 001291164.1_36329001_2 - 7.5 6.8 6.2 26 5.1 6.2 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family ODC_AZ PF02100.15 001290447.1_36322001_3 - 9.8e-15 54.4 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Cu-oxidase_3 PF07732.13 001290447.1_36322001_3 - 0.014 15.3 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase Asp_protease_2 PF13650.4 001291165.1_36329001_1 - 0.016 15.8 0.0 0.026 15.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.15 001291165.1_36329001_2 - 9.6e-15 54.5 1.5 2.7e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291165.1_36329001_2 - 4.1e-14 52.3 0.0 7.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291165.1_36329001_2 - 0.0011 18.8 3.7 0.0017 18.1 3.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291165.1_36329001_2 - 0.0015 18.1 0.2 0.0044 16.6 0.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291165.1_36329001_2 - 0.025 14.3 0.1 0.038 13.7 0.1 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Rootletin PF15035.4 001291165.1_36329001_2 - 0.049 13.6 5.3 0.086 12.8 5.3 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2505 PF10698.7 001291165.1_36329001_2 - 0.063 13.3 0.5 0.11 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) ZapB PF06005.10 001291165.1_36329001_2 - 0.14 12.5 8.5 0.31 11.4 8.5 1.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.19 001291165.1_36329001_2 - 0.2 11.7 3.9 0.52 10.3 3.9 1.7 1 0 0 1 1 1 0 bZIP transcription factor CCDC106 PF15794.3 001291165.1_36329001_2 - 0.22 11.1 1.8 0.36 10.4 1.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001291165.1_36329001_2 - 0.35 11.2 3.1 0.78 10.0 3.1 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001291165.1_36329001_2 - 0.54 10.8 2.4 1.2 9.6 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TolA_bind_tri PF16331.3 001291165.1_36329001_2 - 0.59 10.1 4.0 1.1 9.2 4.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation SlyX PF04102.10 001291165.1_36329001_2 - 0.7 10.4 3.6 1.7 9.2 3.6 1.6 1 0 0 1 1 1 0 SlyX zf-CCHC PF00098.21 001291165.1_36329001_2 - 0.95 9.5 6.7 0.34 10.9 2.2 2.7 2 0 0 2 2 2 0 Zinc knuckle GIT_CC PF16559.3 001291165.1_36329001_2 - 3 7.8 6.5 8.9 6.3 6.5 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.13 001291165.1_36329001_2 - 7.4 6.3 7.0 15 5.3 7.0 1.5 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.16 001291165.1_36329001_2 - 7.5 6.8 6.2 26 5.1 6.2 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family Orn_Arg_deC_N PF02784.14 001293737.1_36324001_3 - 2.4e-69 233.4 0.0 3e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293737.1_36324001_3 - 1.6e-19 69.9 0.0 2.9e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293737.1_36324001_3 - 3.9e-05 23.1 0.0 8.5e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001291536.1_36326001_1 - 3.3e-61 206.7 0.0 4.2e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291536.1_36326001_1 - 1.9e-22 79.3 0.0 3.4e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301796.1_33828001_1 - 5.3e-65 219.2 0.2 6.7e-65 218.8 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301796.1_33828001_1 - 1.6e-22 79.6 0.0 3.4e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ODC_AZ PF02100.15 001290571.1_33822001_2 - 8.9e-15 54.6 0.0 1.3e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Cu-oxidase_3 PF07732.13 001290571.1_33822001_2 - 0.027 14.4 0.0 0.061 13.2 0.0 1.4 1 1 0 1 1 1 0 Multicopper oxidase ODC_AZ PF02100.15 001301631.1_33822001_1 - 9.5e-15 54.5 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Cu-oxidase_3 PF07732.13 001301631.1_33822001_1 - 0.027 14.4 0.0 0.067 13.1 0.0 1.5 1 1 0 1 1 1 0 Multicopper oxidase Asp_protease_2 PF13650.4 001291326.1_33829001_1 - 0.0027 18.2 0.0 0.0044 17.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291326.1_33829001_1 - 0.0051 16.7 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291326.1_33829001_1 - 0.097 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291326.1_33829001_2 - 1.2e-14 54.2 0.1 1.2e-14 54.2 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291326.1_33829001_2 - 1.2e-13 50.8 0.0 2.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001291326.1_33829001_2 - 0.0015 18.0 0.2 0.0043 16.6 0.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CCDC106 PF15794.3 001291326.1_33829001_2 - 0.07 12.7 2.0 0.14 11.7 2.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Rootletin PF15035.4 001291326.1_33829001_2 - 0.82 9.6 16.0 1.8 8.5 16.0 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.10 001291326.1_33829001_2 - 0.86 10.1 8.9 2.4 8.7 8.9 1.7 1 0 0 1 1 1 0 SlyX zf-CCHC PF00098.21 001291326.1_33829001_2 - 1 9.4 7.1 0.31 11.1 2.2 2.7 2 0 0 2 2 2 0 Zinc knuckle DUF972 PF06156.11 001291326.1_33829001_2 - 1.3 9.6 8.0 2.8 8.5 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Uso1_p115_C PF04871.11 001291326.1_33829001_2 - 1.6 9.0 13.6 2.5 8.3 13.6 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.10 001291326.1_33829001_2 - 2.2 8.7 14.0 4.7 7.6 14.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB IncA PF04156.12 001291326.1_33829001_2 - 4.9 6.8 13.7 8.6 6.0 13.7 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.13 001291326.1_33829001_2 - 5.8 6.6 9.2 14 5.4 9.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Asp_protease_2 PF13650.4 001291327.1_33829001_1 - 0.0027 18.2 0.0 0.0044 17.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291327.1_33829001_1 - 0.0051 16.7 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291327.1_33829001_1 - 0.097 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291327.1_33829001_2 - 1.2e-14 54.2 0.1 1.2e-14 54.2 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291327.1_33829001_2 - 1.2e-13 50.8 0.0 2.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001291327.1_33829001_2 - 0.0015 18.0 0.2 0.0043 16.6 0.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CCDC106 PF15794.3 001291327.1_33829001_2 - 0.07 12.7 2.0 0.14 11.7 2.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Rootletin PF15035.4 001291327.1_33829001_2 - 0.82 9.6 16.0 1.8 8.5 16.0 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.10 001291327.1_33829001_2 - 0.86 10.1 8.9 2.4 8.7 8.9 1.7 1 0 0 1 1 1 0 SlyX zf-CCHC PF00098.21 001291327.1_33829001_2 - 1 9.4 7.1 0.31 11.1 2.2 2.7 2 0 0 2 2 2 0 Zinc knuckle DUF972 PF06156.11 001291327.1_33829001_2 - 1.3 9.6 8.0 2.8 8.5 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Uso1_p115_C PF04871.11 001291327.1_33829001_2 - 1.6 9.0 13.6 2.5 8.3 13.6 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.10 001291327.1_33829001_2 - 2.2 8.7 14.0 4.7 7.6 14.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB IncA PF04156.12 001291327.1_33829001_2 - 4.9 6.8 13.7 8.6 6.0 13.7 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.13 001291327.1_33829001_2 - 5.8 6.6 9.2 14 5.4 9.2 1.6 1 0 0 1 1 1 0 Septum formation initiator AhpC-TSA PF00578.19 001287017.1_33822001_1 - 6e-41 139.1 0.0 9.8e-41 138.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001287017.1_33822001_1 - 1.8e-15 56.8 0.0 2.4e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 001287017.1_33822001_1 - 5.6e-15 54.8 0.1 9.3e-15 54.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Endothelin PF00322.15 001287017.1_33822001_1 - 0.17 11.4 0.7 0.37 10.3 0.7 1.5 1 0 0 1 1 1 0 Endothelin family Hormone_1 PF00103.18 001316914.1_33822001_1 - 4e-41 141.0 0.0 5.1e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Orn_Arg_deC_N PF02784.14 001291740.1_33828001_1 - 5.3e-65 219.2 0.2 6.7e-65 218.8 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291740.1_33828001_1 - 2.9e-22 78.7 0.0 6.2e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ald_Xan_dh_C2 PF02738.16 001287018.1_33828001_1 - 2.3e-189 630.3 0.0 3.1e-189 629.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001287018.1_33828001_1 - 1.6e-43 148.3 0.0 4.3e-43 146.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.18 001287018.1_33828001_1 - 1.4e-30 104.9 0.6 4.3e-30 103.3 0.6 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001287018.1_33828001_1 - 1.4e-29 102.2 0.0 4.5e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.20 001287018.1_33828001_1 - 1.8e-25 89.3 1.1 1.4e-16 60.7 0.0 2.9 1 1 1 2 2 2 2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.25 001287018.1_33828001_1 - 1.3e-09 37.8 1.5 1.1e-08 34.7 0.0 2.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Orn_Arg_deC_N PF02784.14 001293726.1_51325001_1 - 3.3e-71 239.5 0.0 4.1e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293726.1_51325001_1 - 3.9e-19 68.7 0.0 6.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293726.1_51325001_1 - 0.00024 20.5 0.0 0.00051 19.4 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AAA_18 PF13238.4 001286154.1_51322001_3 - 4.7e-31 107.9 0.3 1.1e-30 106.7 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.4 001286154.1_51322001_3 - 2.2e-06 28.0 0.1 4.8e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.27 001286154.1_51322001_3 - 7.2e-05 23.1 0.1 0.00033 20.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.4 001286154.1_51322001_3 - 0.00033 20.8 0.0 0.00051 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.20 001286154.1_51322001_3 - 0.0013 18.7 3.0 0.028 14.4 0.1 2.6 2 1 1 3 3 3 1 Shikimate kinase AAA_16 PF13191.4 001286154.1_51322001_3 - 0.0018 18.5 0.2 0.0039 17.4 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 001286154.1_51322001_3 - 0.0023 18.0 0.1 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.4 001286154.1_51322001_3 - 0.0064 16.5 0.3 0.069 13.2 0.2 2.2 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.15 001286154.1_51322001_3 - 0.007 15.9 1.2 0.038 13.5 0.1 2.0 2 0 0 2 2 2 1 Thymidylate kinase NTPase_1 PF03266.13 001286154.1_51322001_3 - 0.01 15.6 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.12 001286154.1_51322001_3 - 0.018 14.9 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.20 001286154.1_51322001_3 - 0.027 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.15 001286154.1_51322001_3 - 0.038 13.8 0.2 0.067 13.1 0.2 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.17 001286154.1_51322001_3 - 0.039 13.7 3.6 1.8 8.2 0.6 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_24 PF13479.4 001286154.1_51322001_3 - 0.04 13.5 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ADK PF00406.20 001286154.1_51322001_3 - 0.044 13.8 0.1 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase RuvB_N PF05496.10 001286154.1_51322001_3 - 0.049 12.8 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.4 001286154.1_51322001_3 - 0.07 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.11 001286154.1_51322001_3 - 0.091 12.0 0.8 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 KaiC Cytidylate_kin PF02224.16 001286154.1_51322001_3 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_19 PF13245.4 001286154.1_51322001_3 - 0.12 12.5 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.9 001286154.1_51322001_3 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IL1 PF00340.17 001279256.1_51322001_2 - 6.6e-41 138.6 0.5 1.5e-40 137.5 0.1 1.8 2 0 0 2 2 2 1 Interleukin-1 / 18 IL1_propep PF02394.14 001279256.1_51322001_2 - 6.1e-36 123.5 0.1 1.8e-35 122.0 0.0 1.8 2 0 0 2 2 2 1 Interleukin-1 propeptide TNF PF00229.16 001279259.1_51322001_1 - 1.6e-39 134.6 0.0 2.1e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DUF846 PF05832.10 001281940.1_51322001_3 - 1.6e-55 186.8 9.6 2.1e-55 186.4 9.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMC PF07810.11 001281940.1_51322001_3 - 0.028 14.9 0.1 0.028 14.9 0.1 1.7 2 0 0 2 2 2 0 TMC domain TMEM192 PF14802.4 001281940.1_51322001_3 - 0.039 12.9 0.2 0.069 12.1 0.2 1.4 1 0 0 1 1 1 0 TMEM192 family HXXEE PF13787.4 001281940.1_51322001_3 - 5.4 7.7 9.4 6.7 7.4 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif TFIID-31kDa PF02291.13 001286153.1_51323001_3 - 9.5e-51 170.8 0.0 1.3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001286153.1_51323001_3 - 1.7e-07 31.6 0.3 3.5e-07 30.7 0.3 1.5 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001286153.1_51323001_3 - 2.8e-06 27.5 0.1 5.4e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.11 001286153.1_51323001_3 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001286153.1_51323001_3 - 0.00022 21.5 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Histone PF00125.22 001286153.1_51323001_3 - 0.00034 20.9 0.3 0.00063 20.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 AAA_17 PF13207.4 001286153.1_51323001_3 - 0.00051 20.3 0.1 0.00051 20.3 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.4 001286153.1_51323001_3 - 0.00057 20.0 0.0 0.00086 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain CENP-T_C PF15511.4 001286153.1_51323001_3 - 0.0041 17.1 0.1 0.0071 16.3 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001286153.1_51323001_3 - 0.0069 16.6 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 001286153.1_51323001_3 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.4 001286153.1_51323001_3 - 0.021 14.8 0.5 0.085 12.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain SKI PF01202.20 001286153.1_51323001_3 - 0.023 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.13 001286153.1_51323001_3 - 0.024 14.4 0.2 0.039 13.7 0.2 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.12 001286153.1_51323001_3 - 0.032 14.1 0.1 0.068 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.15 001286153.1_51323001_3 - 0.049 13.5 0.2 0.099 12.5 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.4 001286153.1_51323001_3 - 0.073 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.10 001286153.1_51323001_3 - 0.076 12.1 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_32 PF13654.4 001286153.1_51323001_3 - 0.11 11.1 0.2 0.91 8.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.11 001286153.1_51323001_3 - 0.12 11.5 0.2 0.51 9.5 0.0 1.9 2 0 0 2 2 2 0 KaiC ODC_AZ PF02100.15 001290025.1_51324001_2 - 3.7e-20 71.9 0.0 7.6e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Orn_Arg_deC_N PF02784.14 001301741.1_51329001_2 - 3.6e-64 216.4 0.1 4.6e-64 216.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301741.1_51329001_2 - 8.5e-25 86.9 0.0 1.5e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain RNase_H PF00075.22 001285848.1_51322001_1 - 1e-44 152.1 0.0 1.7e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285848.1_51322001_1 - 5.7e-19 68.0 0.6 1.1e-18 67.1 0.6 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285848.1_51322001_1 - 0.00012 21.7 0.0 0.00031 20.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like Orn_Arg_deC_N PF02784.14 001291514.1_51329001_3 - 3.8e-64 216.4 0.1 4.9e-64 216.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291514.1_51329001_3 - 8.9e-25 86.8 0.0 1.6e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ODC_AZ PF02100.15 001289805.1_51322001_3 - 5.1e-20 71.4 0.0 8.2e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Pro_CA PF00484.17 001289805.1_51322001_3 - 0.052 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Carbonic anhydrase E1-E2_ATPase PF00122.18 027839.1_45729120_3 - 1.3e-64 217.4 2.7 4.8e-64 215.6 1.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.19 027839.1_45729120_3 - 4.5e-46 156.7 2.2 1e-45 155.6 2.2 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.4 027839.1_45729120_3 - 6.5e-21 74.1 0.5 1.1e-20 73.4 0.5 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.24 027839.1_45729120_3 - 2.9e-17 63.5 0.0 2e-16 60.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 027839.1_45729120_3 - 1.9e-16 59.3 0.9 7e-16 57.5 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.10 027839.1_45729120_3 - 3.3e-05 23.6 0.5 6.4e-05 22.7 0.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.5 027839.1_45729120_3 - 0.00068 19.9 0.0 0.0022 18.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Myosin_tail_1 PF01576.17 015344.1_21022120_1 - 1.9e-09 35.8 14.4 2.3e-09 35.6 14.4 1.0 1 0 0 1 1 1 1 Myosin tail Alanine_zipper PF11839.6 015344.1_21022120_1 - 0.0001 22.4 4.4 0.0013 18.8 4.4 2.0 1 1 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein Tropomyosin PF00261.18 015344.1_21022120_1 - 0.0048 16.2 17.6 0.047 12.9 7.9 2.0 1 1 1 2 2 2 2 Tropomyosin DUF3635 PF12330.6 015344.1_21022120_1 - 0.0048 17.3 0.9 0.0068 16.8 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) GAT PF03127.12 015344.1_21022120_1 - 0.0091 16.2 1.7 0.017 15.3 1.7 1.4 1 0 0 1 1 1 1 GAT domain Rootletin PF15035.4 015344.1_21022120_1 - 0.017 15.1 13.3 0.07 13.1 7.0 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF3573 PF12097.6 015344.1_21022120_1 - 0.024 13.4 1.1 0.027 13.2 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) APG6 PF04111.10 015344.1_21022120_1 - 0.066 12.5 10.1 0.08 12.2 10.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.12 015344.1_21022120_1 - 0.073 12.8 10.9 0.089 12.5 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ISG65-75 PF11727.6 015344.1_21022120_1 - 0.094 11.8 8.3 0.12 11.5 8.3 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Noelin-1 PF12308.6 015344.1_21022120_1 - 0.33 10.8 4.4 0.28 11.0 3.0 1.6 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF2203 PF09969.7 015344.1_21022120_1 - 0.35 11.4 4.7 0.51 10.9 4.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) SlyX PF04102.10 015344.1_21022120_1 - 0.54 10.8 8.8 16 6.1 0.1 3.0 1 1 1 2 2 2 0 SlyX DUF4337 PF14235.4 015344.1_21022120_1 - 0.6 10.1 5.8 0.85 9.6 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) YtxH PF12732.5 015344.1_21022120_1 - 0.76 10.2 4.6 12 6.4 4.6 2.1 1 1 0 1 1 1 0 YtxH-like protein DUF1664 PF07889.10 015344.1_21022120_1 - 1 9.2 6.3 1.1 9.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OEP PF02321.16 015344.1_21022120_1 - 1.4 8.6 7.8 1.9 8.1 7.8 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein DUF342 PF03961.11 015344.1_21022120_1 - 1.5 7.2 9.1 1.7 7.0 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF948 PF06103.9 015344.1_21022120_1 - 1.9 8.7 4.4 25 5.1 4.2 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.7 015344.1_21022120_1 - 2.9 8.0 10.3 3.3 7.8 4.1 2.6 1 1 1 2 2 2 0 Haemolysin XhlA IncA PF04156.12 015344.1_21022120_1 - 4.9 6.8 15.2 1.9 8.1 3.8 2.0 1 1 1 2 2 2 0 IncA protein Synaptobrevin PF00957.19 015344.1_21022120_1 - 5.9 6.6 7.3 1.6 8.5 3.3 1.9 1 1 1 2 2 2 0 Synaptobrevin Myosin_tail_1 PF01576.17 015344.1_21022120_3 - 1.3e-07 29.8 14.7 1.5e-07 29.6 14.7 1.0 1 0 0 1 1 1 1 Myosin tail Bacillus_HBL PF05791.9 015344.1_21022120_3 - 0.0097 15.5 2.8 0.013 15.1 2.8 1.1 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) LUC7 PF03194.13 015344.1_21022120_3 - 0.021 14.3 4.2 0.024 14.1 4.2 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Apolipoprotein PF01442.16 015344.1_21022120_3 - 0.063 13.1 11.9 0.082 12.7 11.9 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BLOC1_2 PF10046.7 015344.1_21022120_3 - 0.072 13.3 4.9 0.14 12.4 4.9 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.10 015344.1_21022120_3 - 0.11 12.4 5.4 0.15 11.9 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BRI3BP PF14965.4 015344.1_21022120_3 - 0.14 11.5 6.9 1.9 7.9 0.9 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 FlxA PF14282.4 015344.1_21022120_3 - 0.2 11.5 9.6 0.38 10.6 9.6 1.4 1 0 0 1 1 1 0 FlxA-like protein ALMT PF11744.6 015344.1_21022120_3 - 0.5 9.0 7.6 0.67 8.6 7.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Trimer_CC PF08954.9 015344.1_21022120_3 - 0.51 9.8 13.6 0.075 12.5 4.0 2.3 2 0 0 2 2 2 0 Trimerisation motif GreA_GreB_N PF03449.13 015344.1_21022120_3 - 0.59 10.2 10.3 0.99 9.5 10.3 1.4 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Tropomyosin_1 PF12718.5 015344.1_21022120_3 - 0.68 9.9 18.0 1.2 9.1 18.0 1.4 1 1 0 1 1 1 0 Tropomyosin like BshC PF10079.7 015344.1_21022120_3 - 0.71 8.4 9.7 0.87 8.1 9.7 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Exonuc_VII_L PF02601.13 015344.1_21022120_3 - 0.78 9.1 7.0 0.97 8.8 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_13 PF13166.4 015344.1_21022120_3 - 0.87 8.0 8.1 1.1 7.7 8.1 1.0 1 0 0 1 1 1 0 AAA domain Muted PF14942.4 015344.1_21022120_3 - 0.89 9.7 12.1 1.2 9.3 12.1 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ACCA PF03255.12 015344.1_21022120_3 - 0.9 9.3 7.0 0.8 9.4 5.6 1.5 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FUSC PF04632.10 015344.1_21022120_3 - 0.97 7.8 3.5 1.2 7.4 3.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-Q PF13094.4 015344.1_21022120_3 - 1.1 9.3 14.4 2.7 8.0 14.4 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1043 PF06295.10 015344.1_21022120_3 - 1.1 9.1 9.0 1.6 8.6 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Uso1_p115_C PF04871.11 015344.1_21022120_3 - 1.5 9.1 15.6 5.2 7.3 15.5 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF883 PF05957.11 015344.1_21022120_3 - 1.5 9.3 7.0 0.9 10.0 4.9 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.4 015344.1_21022120_3 - 1.6 7.9 7.9 2.7 7.1 7.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Helo_like_N PF17111.3 015344.1_21022120_3 - 1.8 7.7 7.1 2.4 7.4 7.1 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins HemX PF04375.12 015344.1_21022120_3 - 2 7.5 9.2 2.5 7.2 9.2 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase G_path_suppress PF15991.3 015344.1_21022120_3 - 2.2 8.2 13.7 3.1 7.7 13.7 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor XhlA PF10779.7 015344.1_21022120_3 - 2.2 8.4 7.5 0.82 9.8 3.2 2.1 1 1 1 2 2 2 0 Haemolysin XhlA IncA PF04156.12 015344.1_21022120_3 - 2.6 7.7 10.8 4.2 7.0 10.8 1.3 1 0 0 1 1 1 0 IncA protein PspB PF06667.10 015344.1_21022120_3 - 2.8 7.9 4.2 2.4 8.1 3.0 1.5 1 1 1 2 2 2 0 Phage shock protein B Fib_alpha PF08702.8 015344.1_21022120_3 - 3.6 7.6 8.5 6.2 6.9 7.5 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF812 PF05667.9 015344.1_21022120_3 - 4.3 6.0 15.5 5.3 5.7 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HSP70 PF00012.18 015344.1_21022120_3 - 4.4 5.2 9.6 5.6 4.9 9.6 1.0 1 0 0 1 1 1 0 Hsp70 protein BST2 PF16716.3 015344.1_21022120_3 - 6 7.4 14.5 40 4.7 14.5 2.0 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 SlyX PF04102.10 015344.1_21022120_3 - 6.3 7.4 9.6 1.3e+02 3.2 9.6 2.2 1 1 0 1 1 1 0 SlyX Spc7 PF08317.9 015344.1_21022120_3 - 6.6 5.4 13.7 7.8 5.1 13.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.12 015344.1_21022120_3 - 9 6.1 14.9 12 5.8 14.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) 5_nucleotid PF05761.12 015344.1_21022120_3 - 9.9 4.8 7.3 13 4.4 7.3 1.0 1 0 0 1 1 1 0 5' nucleotidase family PNP_UDP_1 PF01048.18 036563.1_21023120_2 - 7.6e-48 162.7 0.0 8.9e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Cupin_1 PF00190.20 036563.1_21023120_2 - 0.07 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF4938 PF16292.3 036563.1_21023120_2 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4938) bZIP_2 PF07716.13 003616.2_21023120_1 - 0.082 12.9 2.7 0.14 12.1 2.7 1.3 1 0 0 1 1 1 0 Basic region leucine zipper MHC_I PF00129.16 003616.2_21023120_2 - 1.2e-78 262.7 4.3 1.6e-78 262.2 4.3 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 003616.2_21023120_2 - 3.3e-16 59.4 2.6 3.6e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.10 003616.2_21023120_2 - 3.1e-06 27.0 0.2 7.5e-06 25.8 0.2 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.4 003616.2_21023120_2 - 9.4e-06 26.0 1.0 0.027 14.9 0.0 2.7 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.23 003616.2_21023120_2 - 0.0013 18.7 0.1 0.0034 17.4 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain MATalpha_HMGbox PF04769.10 003616.2_21023120_2 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box 7tm_1 PF00001.19 073042.1_45726120_1 - 1.1e-46 159.1 0.0 1.5e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4106 PF13388.4 073042.1_45726120_1 - 7.1 5.6 4.8 11 5.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) 7tm_1 PF00001.19 073042.1_45726120_2 - 3.2e-06 26.5 0.4 3.2e-06 26.5 0.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Ribosomal_L24e PF01246.18 001128841.1_22422001_1 - 6.4e-34 115.8 0.7 6.4e-34 115.8 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e VGCC_alpha2 PF08473.9 001082276.1_37928001_3 - 6.8e-215 713.7 1.1 1.5e-214 712.6 1.2 1.6 2 0 0 2 2 2 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.9 001082276.1_37928001_3 - 2.2e-40 137.8 0.3 6.1e-40 136.4 0.2 1.8 2 0 0 2 2 2 1 VWA N-terminal VWA PF00092.26 001082276.1_37928001_3 - 3.9e-21 76.0 0.8 7.2e-21 75.1 0.8 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.4 001082276.1_37928001_3 - 1.9e-15 57.0 0.0 3.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.16 001082276.1_37928001_3 - 5.5e-11 42.6 11.2 6e-09 35.9 0.1 4.1 4 1 0 4 4 4 2 Cache domain VWA_2 PF13519.4 001082276.1_37928001_3 - 7.6e-11 42.5 1.1 4.5e-10 40.0 0.4 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain IFN-gamma PF00714.15 001082276.1_37928001_3 - 0.07 12.8 0.5 0.17 11.6 0.5 1.6 1 0 0 1 1 1 0 Interferon gamma Rgp1 PF08737.8 172866.3_32929001_1 - 5.1e-43 147.7 0.0 5.5e-21 75.1 0.0 2.1 2 0 0 2 2 2 2 Rgp1 Hormone_6 PF00236.16 001032990.1_32322001_2 - 1.3e-52 175.6 11.2 2.1e-52 174.9 11.2 1.4 1 0 0 1 1 1 1 Glycoprotein hormone DUF1218 PF06749.10 001032990.1_32322001_2 - 0.13 12.7 5.7 0.64 10.4 4.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Cyclophil_like PF04126.11 001032990.1_32322001_3 - 0.058 13.1 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Cyclophilin-like 14-3-3 PF00244.18 031603.1_45724001_1 - 2e-103 344.5 2.6 2.4e-103 344.2 2.6 1.1 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.15 031603.1_45724001_1 - 0.11 10.8 2.8 0.16 10.2 2.8 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 MACPF PF01823.17 001009015.1_39726001_1 - 1.2e-46 159.3 2.3 1.4e-46 159.1 0.9 1.8 2 0 0 2 2 2 1 MAC/Perforin domain Sushi PF00084.18 001009015.1_39726001_1 - 1.3e-13 51.2 5.5 6e-09 36.3 1.2 3.8 4 0 0 4 4 4 2 Sushi repeat (SCR repeat) TSP_1 PF00090.17 001009015.1_39726001_1 - 9.8e-13 48.0 20.8 5e-09 36.1 0.7 5.7 6 1 0 6 6 6 3 Thrombospondin type 1 domain Kazal_2 PF07648.13 001009015.1_39726001_1 - 2e-10 40.5 4.0 2e-10 40.5 4.0 3.4 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Ldl_recept_a PF00057.16 001009015.1_39726001_1 - 2.4e-10 40.3 15.6 2.4e-10 40.3 15.6 5.2 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A 7tm_1 PF00001.19 001280858.1_29224001_2 - 1.1e-43 149.3 13.5 1.5e-43 148.9 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.7 001280858.1_29224001_2 - 3e-24 84.4 3.7 1.1e-23 82.6 3.7 2.0 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.7 001280858.1_29224001_2 - 7.7e-09 35.1 15.0 1.6e-08 34.1 15.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.7 001280858.1_29224001_2 - 3.5e-08 33.0 17.7 5.5e-08 32.4 17.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.7 001280858.1_29224001_2 - 1.9e-06 27.3 16.8 2.8e-06 26.8 16.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.11 001280858.1_29224001_2 - 0.0073 15.3 3.5 0.0073 15.3 3.5 2.1 2 0 0 2 2 2 1 Taste receptor protein (TAS2R) 7tm_4 PF13853.4 001280858.1_29224001_2 - 0.02 14.5 15.7 0.085 12.4 15.7 1.8 1 1 0 1 1 1 0 Olfactory receptor Arif-1 PF06770.9 001280858.1_29224001_2 - 0.087 12.4 4.8 0.26 10.8 4.8 1.7 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) TctB PF07331.9 001280858.1_29224001_2 - 0.76 9.9 12.9 1.7 8.7 2.1 2.6 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4407 PF14362.4 001280858.1_29224001_2 - 2.8 7.1 3.7 1.7 7.8 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_S8 PF00082.20 001279999.1_46725001_1 - 5.2e-24 84.9 0.0 1.5e-23 83.4 0.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.14 001279999.1_46725001_1 - 2.8e-06 27.7 0.0 4.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Guanylate_kin PF00625.19 007862.3_32929001_2 - 7.9e-66 221.1 1.3 1.4e-65 220.3 1.3 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.22 007862.3_32929001_2 - 4.2e-61 203.1 8.0 2.1e-19 69.5 0.1 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) MAGUK_N_PEST PF10608.7 007862.3_32929001_2 - 8.4e-55 184.2 8.7 8.4e-55 184.2 8.7 1.8 2 0 0 2 2 2 1 Polyubiquitination (PEST) N-terminal domain of MAGUK L27_1 PF09058.8 007862.3_32929001_2 - 1.4e-29 101.8 4.3 3.4e-29 100.6 4.3 1.7 1 0 0 1 1 1 1 L27_1 PDZ_assoc PF10600.7 007862.3_32929001_2 - 2.1e-24 86.0 3.3 8e-24 84.1 3.3 2.1 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_2 PF13180.4 007862.3_32929001_2 - 4.6e-16 58.8 0.5 0.00034 20.8 0.1 3.6 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.26 007862.3_32929001_2 - 8.3e-08 31.6 0.1 1.9e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 007862.3_32929001_2 - 1.2e-07 31.2 0.0 2.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 007862.3_32929001_2 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Lipocalin PF00061.21 001287019.1_33822001_1 - 2.5e-28 98.9 2.9 3e-28 98.7 2.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001287019.1_33822001_1 - 9e-09 35.2 0.9 1.2e-08 34.8 0.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PHD PF00628.27 001287286.1_29524001_1 - 3.5e-09 36.3 9.4 7.7e-09 35.2 9.4 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.20 001287286.1_29524001_1 - 2.5e-05 24.0 2.9 2.5e-05 24.0 2.9 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.4 001287286.1_29524001_1 - 0.0001 22.0 3.3 0.00028 20.6 3.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.4 001287286.1_29524001_1 - 0.0033 16.8 4.6 0.009 15.4 4.6 1.8 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.3 001287286.1_29524001_1 - 0.0041 17.1 8.5 0.012 15.6 8.5 1.8 1 1 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.4 001287286.1_29524001_1 - 0.0047 16.4 3.6 0.0099 15.4 3.6 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.14 001287286.1_29524001_1 - 4.3 7.4 10.2 0.8 9.8 5.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger ANF_receptor PF01094.26 175768.3_26229001_3 - 2.5e-81 273.4 0.0 3.3e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 175768.3_26229001_3 - 1e-54 184.3 0.2 1.6e-54 183.6 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 175768.3_26229001_3 - 1e-45 154.5 0.0 2.7e-45 153.1 0.0 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 175768.3_26229001_3 - 2e-17 63.3 0.0 3.4e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.4 175768.3_26229001_3 - 1.1e-08 35.0 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_1 PF00001.19 001280659.1_52223001_1 - 1.6e-45 155.3 14.8 2.1e-45 154.9 14.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.7 001280659.1_52223001_1 - 8.2e-24 83.0 2.4 8.2e-24 83.0 2.4 2.0 2 0 0 2 2 2 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srv PF10323.7 001280659.1_52223001_1 - 2.3e-10 40.2 20.0 3.6e-10 39.5 20.0 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.7 001280659.1_52223001_1 - 3e-10 39.8 19.0 2e-09 37.1 19.0 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.7 001280659.1_52223001_1 - 7.7e-09 35.2 18.2 9.8e-09 34.8 18.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.11 001280659.1_52223001_1 - 2.3e-05 23.6 10.5 0.00022 20.3 2.0 2.1 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) 7tm_4 PF13853.4 001280659.1_52223001_1 - 0.0003 20.5 16.0 0.00099 18.8 16.0 1.7 1 1 0 1 1 1 1 Olfactory receptor DUF4407 PF14362.4 001280659.1_52223001_1 - 1.1 8.4 4.6 1.2 8.3 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Arif-1 PF06770.9 001280659.1_52223001_1 - 2.2 7.8 10.7 0.13 11.7 5.3 1.7 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) zf-DHHC PF01529.18 001280659.1_52223001_1 - 4.6 7.2 20.6 0.24 11.4 2.6 3.0 2 1 1 3 3 3 0 DHHC palmitoyltransferase DUF4079 PF13301.4 001280659.1_52223001_1 - 5.3 7.1 9.8 22 5.0 6.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) 7tm_1 PF00001.19 001244407.1_14223001_1 - 1.6e-47 161.9 12.2 2.1e-47 161.5 12.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.7 001244407.1_14223001_1 - 1.5e-23 82.1 3.7 1.5e-23 82.1 3.7 2.2 2 0 0 2 2 2 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.7 001244407.1_14223001_1 - 3.4e-12 46.1 15.8 2.7e-11 43.2 15.8 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.7 001244407.1_14223001_1 - 2.3e-11 43.4 18.0 3.9e-11 42.7 18.0 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.7 001244407.1_14223001_1 - 5.8e-10 38.9 15.7 7.7e-10 38.4 15.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.11 001244407.1_14223001_1 - 6.1e-05 22.1 11.3 0.00037 19.6 3.6 2.1 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) 7tm_4 PF13853.4 001244407.1_14223001_1 - 0.00015 21.5 15.1 0.00099 18.8 15.1 1.9 1 1 0 1 1 1 1 Olfactory receptor 60KD_IMP PF02096.18 001244407.1_14223001_1 - 0.36 10.6 6.6 2.7 7.8 5.8 2.5 1 1 0 1 1 1 0 60Kd inner membrane protein 7TM_GPCR_Srh PF10318.7 001244407.1_14223001_1 - 2.9 6.7 29.5 27 3.5 29.5 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF4079 PF13301.4 001244407.1_14223001_1 - 4.8 7.2 7.4 29 4.7 3.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) TctB PF07331.9 001244407.1_14223001_1 - 8.3 6.5 20.4 19 5.4 5.3 2.7 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family LEDGF PF11467.6 008233.4_32925001_2 - 2.8e-28 97.9 1.9 4.7e-28 97.1 1.9 1.3 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.15 008233.4_32925001_2 - 9e-15 54.8 0.1 3.7e-14 52.8 0.1 2.1 1 0 0 1 1 1 1 PWWP domain Casein PF00363.16 001303561.1_08522001_1 - 6.5e-22 77.9 17.8 2.1e-17 63.4 6.0 2.6 2 1 0 2 2 2 2 Casein SapC PF07277.9 001303561.1_08522001_1 - 0.037 13.5 0.2 0.062 12.7 0.2 1.3 1 0 0 1 1 1 0 SapC UPF0239 PF06783.9 001303561.1_08522001_1 - 1.8 8.7 4.3 0.57 10.3 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Cys_knot PF00007.20 001308527.1_02621001_1 - 5.6e-33 113.3 17.3 7.1e-33 112.9 17.3 1.1 1 0 0 1 1 1 1 Cystine-knot domain HMG_box_5 PF14887.4 001244013.1_14225001_1 - 1.2e-55 185.3 45.0 4e-53 177.2 7.3 5.8 5 1 1 6 6 6 3 HMG (high mobility group) box 5 HMG_box PF00505.17 001244013.1_14225001_1 - 6.6e-54 180.1 64.9 1.2e-17 63.9 7.0 7.6 6 1 1 7 7 7 6 HMG (high mobility group) box HMG_box_2 PF09011.8 001244013.1_14225001_1 - 4.4e-28 97.5 56.9 2.7e-08 34.2 0.2 7.3 6 1 1 7 7 7 6 HMG-box domain DUF4473 PF14747.4 001244013.1_14225001_1 - 0.0014 19.0 0.5 0.0014 19.0 0.5 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4473) Chlor_dismutase PF06778.10 001244013.1_14225001_1 - 0.8 9.1 6.8 0.39 10.1 0.0 2.8 3 0 0 3 3 3 0 Chlorite dismutase DUF1074 PF06382.9 001244013.1_14225001_1 - 2.3 8.3 24.4 1.7 8.7 0.3 5.4 4 2 1 5 5 5 0 Protein of unknown function (DUF1074) DUF1298 PF06974.11 001244013.1_14225001_2 - 2.4 8.0 4.4 4.5 7.1 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) IQ PF00612.25 001323027.1_26225001_2 - 0.00024 20.5 0.5 0.00064 19.2 0.5 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif ODC_AZ PF02100.15 001301636.1_42222001_3 - 1.6e-14 53.8 0.0 2.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme HLH PF00010.24 178161.2_26223001_1 - 2.4e-18 65.7 0.1 2.4e-18 65.7 0.1 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Caldesmon PF02029.13 153845.1_32923120_1 - 8.8e-06 24.6 32.4 1.1e-05 24.3 32.4 1.1 1 0 0 1 1 1 1 Caldesmon DDHD PF02862.15 153845.1_32923120_1 - 0.0022 18.0 8.4 0.0033 17.5 8.4 1.4 1 0 0 1 1 1 1 DDHD domain Nop14 PF04147.10 153845.1_32923120_1 - 0.0027 15.9 39.7 0.0035 15.5 39.7 1.0 1 0 0 1 1 1 1 Nop14-like family SID-1_RNA_chan PF13965.4 153845.1_32923120_1 - 0.007 14.8 0.2 0.0089 14.4 0.2 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Presenilin PF01080.15 153845.1_32923120_1 - 0.025 13.2 23.8 0.036 12.7 23.8 1.2 1 0 0 1 1 1 0 Presenilin DUF1510 PF07423.9 153845.1_32923120_1 - 0.031 13.6 46.4 0.047 13.0 46.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.8 153845.1_32923120_1 - 0.031 13.5 42.7 0.043 13.0 42.7 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.13 153845.1_32923120_1 - 0.04 12.6 17.9 0.049 12.3 17.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nha1_C PF08619.8 153845.1_32923120_1 - 0.16 11.0 31.2 0.22 10.5 31.2 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus SDA1 PF05285.10 153845.1_32923120_1 - 0.22 10.8 48.6 0.31 10.3 48.6 1.1 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.11 153845.1_32923120_1 - 0.52 8.9 31.8 0.75 8.4 31.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.5 153845.1_32923120_1 - 0.59 9.8 24.0 0.95 9.1 24.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Smg8_Smg9 PF10220.7 153845.1_32923120_1 - 0.62 8.2 16.9 0.77 7.9 16.9 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Spore_coat_CotO PF14153.4 153845.1_32923120_1 - 1.4 8.7 37.3 2.1 8.1 37.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4045 PF13254.4 153845.1_32923120_1 - 1.6 8.2 26.7 2.2 7.7 26.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF262 PF03235.12 153845.1_32923120_1 - 3.2 7.7 13.5 4.2 7.3 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 FAM60A PF15396.4 153845.1_32923120_1 - 3.2 7.6 22.2 4.7 7.0 22.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CDC27 PF09507.8 153845.1_32923120_1 - 4.1 6.6 42.5 5.6 6.1 42.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Rrn6 PF10214.7 153845.1_32923120_1 - 4.2 5.5 13.3 5.4 5.2 13.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Raftlin PF15250.4 153845.1_32923120_1 - 5.7 5.4 20.6 7.6 5.0 20.6 1.1 1 0 0 1 1 1 0 Raftlin Cwf_Cwc_15 PF04889.10 153845.1_32923120_1 - 5.7 6.5 38.1 8.2 5.9 38.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.8 153845.1_32923120_1 - 6.4 6.9 39.9 13 5.9 39.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.12 153845.1_32923120_2 - 2.6 8.4 10.5 4.1 7.7 10.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop53 PF07767.9 153845.1_32923120_3 - 2 7.6 10.8 2.7 7.2 10.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Rrn6 PF10214.7 153845.1_32923120_3 - 7.8 4.6 11.6 10 4.3 11.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GalP_UDP_tr_C PF02744.15 016658.3_32925001_2 - 2.1e-65 219.4 0.1 3.4e-65 218.7 0.1 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.20 016658.3_32925001_2 - 1.5e-64 217.7 0.0 2.4e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.21 016658.3_32925001_2 - 0.0052 17.4 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 HIT domain MHC_I_3 PF16497.3 001128836.1_08922001_1 - 2.2e-76 255.7 0.1 2.7e-76 255.3 0.1 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.13 001128836.1_08922001_1 - 6e-12 45.7 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001128836.1_08922001_1 - 4.8e-06 26.1 0.0 7.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 ig PF00047.23 001128836.1_08922001_1 - 0.0047 16.9 0.0 0.015 15.3 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001128836.1_08922001_1 - 0.0088 16.5 0.0 0.027 15.0 0.0 1.8 1 1 1 2 2 2 1 Immunoglobulin domain MRI PF15325.4 001246792.1_14221001_1 - 6.8e-44 149.2 0.1 1e-43 148.7 0.1 1.2 1 0 0 1 1 1 1 Modulator of retrovirus infection PTPLA PF04387.12 131895.1_08922120_1 - 9.3e-27 93.7 2.9 1.2e-26 93.3 2.9 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PTPLA PF04387.12 131895.1_08922120_3 - 2.4e-11 43.5 1.1 2.4e-11 43.5 1.1 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA NB-ARC PF00931.20 181868.1_26229001_2 - 3.8e-81 272.1 1.1 5.8e-81 271.5 1.1 1.3 1 0 0 1 1 1 1 NB-ARC domain WD40 PF00400.30 181868.1_26229001_2 - 1.2e-58 193.6 40.5 2.1e-08 34.6 0.2 12.5 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 181868.1_26229001_2 - 4.4e-25 87.7 11.1 0.00077 19.6 0.1 8.6 5 4 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain CARD PF00619.19 181868.1_26229001_2 - 8.8e-19 67.2 0.2 2e-18 66.0 0.2 1.7 1 0 0 1 1 1 1 Caspase recruitment domain Ge1_WD40 PF16529.3 181868.1_26229001_2 - 3e-10 39.4 5.4 0.36 9.6 0.1 7.2 5 2 1 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.3 181868.1_26229001_2 - 3.5e-09 36.3 0.5 0.0065 15.7 0.1 3.6 2 1 1 3 3 3 3 WD40-like domain CARD_2 PF16739.3 181868.1_26229001_2 - 1.8e-08 34.1 0.1 4.3e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Caspase recruitment domain AAA_16 PF13191.4 181868.1_26229001_2 - 3.1e-05 24.3 0.0 5.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Nbas_N PF15492.4 181868.1_26229001_2 - 0.03 13.5 0.0 5.5 6.1 0.0 2.9 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal NACHT PF05729.10 181868.1_26229001_2 - 0.094 12.5 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.4 181868.1_26229001_2 - 0.1 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cactin_mid PF10312.7 181868.1_26229001_2 - 0.12 11.9 0.4 0.35 10.4 0.4 1.7 1 1 0 1 1 1 0 Conserved mid region of cactin SIM_C PF06621.10 011376.3_32929001_1 - 2.4e-110 369.1 16.3 3.8e-110 368.4 16.3 1.3 1 0 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.10 011376.3_32929001_1 - 2.5e-24 85.2 2.4 3.6e-18 65.5 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.4 011376.3_32929001_1 - 2.5e-19 69.3 0.4 3.6e-14 52.7 0.1 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 011376.3_32929001_1 - 8.9e-17 61.0 0.0 2.6e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.24 011376.3_32929001_1 - 1.8e-05 24.5 0.7 0.00011 21.9 0.8 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 011376.3_32929001_1 - 0.00031 20.8 0.0 0.058 13.5 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.8 011376.3_32929001_1 - 0.0086 16.2 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold DUF3772 PF12607.6 011376.3_32929001_2 - 0.12 12.1 0.4 0.21 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) PP1_inhibitor PF05361.10 033256.2_26222001_1 - 2e-58 196.3 0.1 2.6e-58 195.9 0.1 1.1 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Sec7 PF01369.18 001114664.2_32929001_2 - 9.8e-56 188.2 0.0 1.7e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.3 001114664.2_32929001_2 - 1.8e-51 173.6 0.4 4.1e-51 172.5 0.2 1.8 2 0 0 2 2 2 1 PH domain SlyX PF04102.10 001114664.2_32929001_2 - 0.25 11.8 5.3 1.4 9.5 5.3 2.4 1 0 0 1 1 1 0 SlyX Atg14 PF10186.7 001114664.2_32929001_2 - 1.2 8.0 5.2 2.7 6.8 5.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TLV_coat PF00429.17 001305653.1_34024001_1 - 4.4e-58 197.2 15.2 8.1e-56 189.7 2.2 2.6 3 0 0 3 3 3 2 ENV polyprotein (coat polyprotein) PRY PF13765.4 001132780.1_43526001_2 - 4.4e-22 77.3 0.7 8.3e-22 76.4 0.7 1.5 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.26 001132780.1_43526001_2 - 3.7e-13 49.5 0.0 6.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain V-set PF07686.15 001132780.1_43526001_2 - 8.7e-13 48.3 0.0 1.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001132780.1_43526001_2 - 2.4e-05 24.7 0.0 0.00027 21.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001132780.1_43526001_2 - 0.00058 19.8 0.1 0.0052 16.8 0.1 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001132780.1_43526001_2 - 0.0014 18.8 0.0 0.0065 16.7 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001132780.1_43526001_2 - 0.024 14.5 0.0 0.083 12.8 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin I-set domain DUF4446 PF14584.4 001132780.1_43526001_2 - 0.045 13.6 0.9 0.071 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Izumo-Ig PF16706.3 001132780.1_43526001_2 - 0.14 12.1 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain TLV_coat PF00429.17 001305453.1_05825001_2 - 6.8e-18 64.5 2.4 1.5e-17 63.4 0.4 2.2 2 1 0 2 2 2 1 ENV polyprotein (coat polyprotein) QueC PF06508.11 001305453.1_05825001_2 - 0.018 14.4 0.2 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC GP41 PF00517.15 001305453.1_05825001_2 - 0.044 13.5 0.6 0.083 12.6 0.6 1.4 1 0 0 1 1 1 0 Retroviral envelope protein SASA PF03629.16 170601.4_26226001_3 - 2.4e-14 53.4 0.0 5.5e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase LRR_9 PF14580.4 001144865.1_39725001_2 - 7.6e-12 44.9 0.0 2.4e-11 43.3 0.0 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.4 001144865.1_39725001_2 - 1.9e-06 27.4 1.5 1.9e-06 27.4 1.5 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001144865.1_39725001_2 - 0.00026 21.2 4.6 0.0053 17.0 0.3 3.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Trypsin PF00089.24 001172932.1_09922001_2 - 7.2e-54 182.8 0.0 8.3e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001172932.1_09922001_2 - 0.00044 21.0 0.0 0.0013 19.5 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S29 PF02907.13 001172932.1_09922001_2 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease TLV_coat PF00429.17 001305587.1_26724001_1 - 6.2e-14 51.5 0.8 6.6e-13 48.1 0.3 2.5 2 1 0 2 2 2 1 ENV polyprotein (coat polyprotein) DUF4006 PF13179.4 001305587.1_26724001_1 - 0.027 14.2 0.2 0.052 13.3 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Lipocalin PF00061.21 001290964.1_07322001_1 - 1.1e-37 129.3 0.0 1.3e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family TLV_coat PF00429.17 001305590.1_01323001_1 - 4.3e-09 35.5 8.3 8.9e-08 31.1 8.2 2.7 1 1 0 1 1 1 1 ENV polyprotein (coat polyprotein) GP41 PF00517.15 001305590.1_01323001_1 - 0.049 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Retroviral envelope protein Corona_S2 PF01601.14 001305590.1_01323001_1 - 0.85 7.9 7.1 1.4 7.2 7.1 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PilX_N PF14341.4 001305590.1_01323001_1 - 5.7 6.8 5.4 1.2 9.0 0.3 2.1 2 0 0 2 2 2 0 PilX N-terminal Neugrin PF06413.9 028055.1_45724120_2 - 4.6e-88 294.9 0.6 5.8e-88 294.5 0.6 1.1 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.5 028055.1_45724120_2 - 0.0025 17.9 1.8 0.0039 17.2 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 AAR2 PF05282.9 028055.1_45724120_2 - 0.2 10.9 1.4 12 5.0 0.0 2.5 2 1 1 3 3 3 0 AAR2 protein V-set PF07686.15 145981.2_49824120_3 - 1.6e-16 60.3 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 145981.2_49824120_3 - 1e-09 38.7 0.0 3.3e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 145981.2_49824120_3 - 7.4e-06 25.9 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 145981.2_49824120_3 - 7.6e-06 25.8 0.0 3.1e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.4 145981.2_49824120_3 - 0.014 15.6 0.2 0.2 11.9 0.2 2.4 1 1 0 1 1 1 0 Immunoglobulin domain zf-H2C2_2 PF13465.4 001965.3_26225001_1 - 3.2e-12 46.2 7.9 3.4e-07 30.3 0.8 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001965.3_26225001_1 - 1.6e-10 40.7 13.9 0.0047 17.5 2.4 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.24 001965.3_26225001_1 - 5.5e-10 39.0 22.4 0.001 19.3 3.8 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 001965.3_26225001_1 - 0.0002 21.1 5.1 0.41 10.5 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001965.3_26225001_1 - 0.015 15.5 6.3 0.03 14.5 3.6 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.5 001965.3_26225001_1 - 0.054 13.8 11.1 0.28 11.5 1.4 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.4 001965.3_26225001_1 - 0.099 12.4 8.7 4.4 7.2 0.5 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zf_RING PF16744.3 001965.3_26225001_1 - 0.14 12.2 1.5 2.6 8.1 0.1 2.3 1 1 1 2 2 2 0 KIAA1045 RING finger DUF3446 PF11928.6 001965.3_26225001_1 - 2.1 8.6 10.4 1.5 9.1 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) zf-C2H2_11 PF16622.3 001965.3_26225001_1 - 6.8 6.4 7.7 22 4.8 0.2 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type Defensin_propep PF00879.16 001141941.1_40421001_1 - 7.9e-23 80.4 6.4 9.8e-23 80.1 6.4 1.1 1 0 0 1 1 1 1 Defensin propeptide Glyco_transf_7N PF13733.4 004776.3_26229001_3 - 8.3e-53 177.5 0.0 1.2e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.12 004776.3_26229001_3 - 1.5e-28 98.1 0.4 3e-28 97.1 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase 7tm_1 PF00001.19 001279979.1_46723001_1 - 3.1e-59 200.3 28.5 4.5e-59 199.7 28.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001279979.1_46723001_1 - 3.3e-09 36.4 27.1 4.1e-09 36.1 27.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001279979.1_46723001_1 - 4.8e-06 25.9 27.9 7.4e-06 25.3 27.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001279979.1_46723001_1 - 0.0012 18.5 20.9 0.0029 17.3 20.9 1.5 1 1 0 1 1 1 1 Olfactory receptor MWFE PF15879.3 001279979.1_46723001_1 - 0.18 11.9 0.9 0.92 9.6 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF4347 PF14252.4 001270628.1_45726001_1 - 0.00058 19.6 0.0 0.00092 18.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) SNURF PF07192.9 001287684.1_29523001_1 - 5.5e-45 150.9 6.1 9.2e-45 150.2 6.1 1.4 1 0 0 1 1 1 1 SNURF/RPN4 protein LSM PF01423.20 001287684.1_29523001_3 - 1e-19 69.8 0.1 1.4e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Casein PF00363.16 001172894.1_09923001_2 - 5.8e-19 68.4 1.2 5.8e-19 68.4 1.2 2.5 3 0 0 3 3 3 2 Casein YtzH PF14165.4 001172894.1_09923001_2 - 0.016 15.4 1.4 0.026 14.8 0.3 1.9 2 0 0 2 2 2 0 YtzH-like protein EspB PF05802.9 001172894.1_09923001_2 - 0.027 13.5 0.8 0.049 12.6 0.8 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein Globin PF00042.20 001085432.1_21021001_1 - 3.8e-29 101.3 0.1 5.3e-29 100.9 0.1 1.2 1 0 0 1 1 1 1 Globin DEAD PF00270.27 001357703.1_32929001_1 - 3.3e-42 144.1 0.7 1.7e-41 141.8 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001357703.1_32929001_1 - 7.6e-27 93.8 0.8 2.6e-26 92.0 0.5 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.4 001357703.1_32929001_1 - 0.0029 16.9 0.2 0.0049 16.1 0.2 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Aldedh PF00171.20 001290159.1_20625001_1 - 9.9e-183 607.7 0.1 1.1e-182 607.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.12 001290159.1_20625001_1 - 0.00018 20.6 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.9 001290159.1_20625001_1 - 0.051 12.9 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TAS2R PF05296.11 001039857.1_32322001_1 - 7.2e-84 281.3 44.4 8.1e-84 281.2 44.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) TAS2R PF05296.11 001039874.1_32322001_1 - 7.9e-81 271.3 33.5 9.5e-81 271.1 33.5 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) CTNNB1_binding PF08347.9 001039874.1_32322001_3 - 0.031 14.3 0.7 0.04 14.0 0.7 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding 7tm_3 PF00003.20 001099547.1_32325001_1 - 6.1e-66 222.4 19.3 9.8e-66 221.8 19.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099547.1_32325001_1 - 2.6e-51 174.7 0.0 3.7e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099547.1_32325001_1 - 1.4e-15 56.9 12.1 2.7e-15 55.9 12.1 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099547.1_32325001_1 - 0.064 12.9 6.2 0.17 11.5 6.2 1.7 1 0 0 1 1 1 0 Putative ephrin-receptor like DUF3611 PF12263.6 001099547.1_32325001_1 - 7 6.4 11.0 0.038 13.7 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) 7tm_3 PF00003.20 001099543.1_32325001_1 - 5.7e-62 209.4 27.3 9.7e-62 208.7 27.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099543.1_32325001_1 - 2e-53 181.6 0.0 2.6e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099543.1_32325001_1 - 2e-18 65.9 12.9 4.4e-18 64.9 12.9 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099543.1_32325001_1 - 0.0043 16.7 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.20 001099577.1_32326001_1 - 3.1e-60 203.7 27.6 5.3e-60 203.0 27.6 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099577.1_32326001_1 - 3.2e-48 164.5 0.0 4.3e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099577.1_32326001_1 - 6.4e-18 64.3 15.9 1.4e-17 63.3 15.9 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099577.1_32326001_1 - 0.052 13.1 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF2157 PF09925.7 001099577.1_32326001_1 - 1.7 8.3 7.8 9.6 5.9 0.9 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) ANF_receptor PF01094.26 001099569.1_32325001_1 - 3.3e-56 190.8 0.0 4.4e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.20 001099569.1_32325001_1 - 4.7e-56 190.1 22.8 8e-56 189.3 22.8 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.12 001099569.1_32325001_1 - 6.7e-20 70.7 12.9 1.4e-19 69.7 12.9 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099569.1_32325001_1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Ephrin_rec_like PF07699.11 001099569.1_32325001_1 - 0.015 15.0 5.1 0.015 15.0 5.1 2.3 1 1 1 2 2 2 0 Putative ephrin-receptor like 7tm_1 PF00001.19 001127627.1_37623001_1 - 5.8e-45 153.5 13.5 7.4e-45 153.1 13.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.7 001127627.1_37623001_1 - 7.6e-26 89.5 2.8 7.6e-26 89.5 2.8 2.2 2 0 0 2 2 2 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.7 001127627.1_37623001_1 - 1.4e-08 34.3 19.9 6.1e-08 32.2 19.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.7 001127627.1_37623001_1 - 1.5e-07 31.0 21.8 2.9e-07 30.0 21.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.7 001127627.1_37623001_1 - 5.4e-07 29.1 19.8 7.4e-07 28.7 19.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.11 001127627.1_37623001_1 - 0.0023 17.0 3.4 0.0023 17.0 3.4 2.1 2 0 0 2 2 2 1 Taste receptor protein (TAS2R) 7tm_4 PF13853.4 001127627.1_37623001_1 - 0.02 14.5 16.7 0.093 12.3 16.7 1.8 1 1 0 1 1 1 0 Olfactory receptor DUF4407 PF14362.4 001127627.1_37623001_1 - 0.55 9.4 3.0 0.48 9.6 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4079 PF13301.4 001127627.1_37623001_1 - 3.6 7.6 7.1 7.7 6.5 3.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) 7tm_3 PF00003.20 001102429.1_32325001_1 - 1.2e-61 208.4 29.4 4.6e-61 206.5 28.7 2.3 3 0 0 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102429.1_32325001_1 - 5.4e-47 160.5 0.0 7.3e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102429.1_32325001_1 - 1.2e-16 60.2 11.7 2.5e-16 59.2 11.7 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001102429.1_32325001_1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF1600 PF07667.9 001102429.1_32325001_1 - 0.43 10.7 5.8 0.068 13.2 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) V1R PF03402.12 001167518.1_32322001_1 - 2.3e-28 99.4 22.0 3.1e-28 99.0 22.0 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167518.1_32322001_1 - 3.9e-17 62.2 32.0 4.4e-17 62.0 32.0 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001167518.1_32322001_1 - 3.6e-05 23.0 24.6 5.4e-05 22.4 24.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001167300.1_37922001_1 - 2.8e-65 220.4 26.9 3.4e-65 220.2 26.9 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167300.1_37922001_1 - 0.013 14.5 30.8 0.021 13.8 30.8 1.3 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) V1R PF03402.12 001166799.1_32322001_1 - 4.1e-34 118.3 9.1 5.7e-34 117.8 9.1 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001166799.1_32322001_1 - 6e-15 55.0 14.8 7.3e-15 54.7 14.8 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001166832.1_32322001_1 - 1.6e-32 113.0 11.4 2.3e-32 112.5 11.4 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001166832.1_32322001_1 - 3e-15 56.0 19.0 3.6e-15 55.7 19.0 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001166832.1_32322001_1 - 0.00025 20.3 14.6 0.00038 19.7 14.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001171439.1_37922001_1 - 1.4e-121 405.4 24.5 1.7e-121 405.1 24.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001171439.1_37922001_1 - 2.4e-16 59.6 24.2 5.8e-16 58.4 24.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001171439.1_37922001_1 - 0.0018 17.6 22.0 0.0025 17.1 22.0 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001171458.1_37922001_1 - 4.2e-114 380.8 22.4 5e-114 380.6 22.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001171458.1_37922001_1 - 2.4e-17 62.9 21.3 1.2e-16 60.6 21.3 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001171458.1_37922001_1 - 2e-08 33.8 7.7 2e-08 33.8 7.7 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx ubiquitin PF00240.21 001171468.1_37924001_1 - 2.7e-18 65.3 0.3 5.4e-18 64.4 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.29 001171468.1_37924001_1 - 3.4e-06 26.7 0.1 1.1e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.6 001171468.1_37924001_1 - 1.6e-05 24.5 0.2 2.6e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.4 001171468.1_37924001_1 - 0.0026 17.7 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001171468.1_37924001_1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain YukD PF08817.8 001171468.1_37924001_1 - 0.0089 16.6 0.0 0.025 15.1 0.0 1.8 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD YopE_N PF09020.8 001171468.1_37924001_1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 YopE, N terminal HOIP-UBA PF16678.3 001171468.1_37924001_1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase 7tm_4 PF13853.4 001171470.1_37922001_1 - 3.4e-108 361.5 25.1 3.9e-108 361.3 25.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001171470.1_37922001_1 - 4.1e-20 72.0 27.0 1.3e-19 70.4 27.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001171470.1_37922001_1 - 2.4e-06 27.0 22.9 4.5e-06 26.1 22.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1418 PF07214.10 001171470.1_37922001_1 - 1.4 8.8 4.5 4.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) 7tm_4 PF13853.4 001171477.1_37922001_1 - 1.8e-106 355.8 19.5 2.2e-106 355.6 19.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001171477.1_37922001_1 - 1.9e-19 69.8 18.9 4e-19 68.7 18.9 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001171477.1_37922001_1 - 9.3e-11 41.5 16.5 1.3e-10 41.0 15.8 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DNA_ligase_A_N PF04675.12 001171477.1_37922001_1 - 0.036 14.3 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 DNA ligase N terminus DUF4083 PF13314.4 001171477.1_37922001_1 - 4.5 7.2 5.2 0.94 9.3 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Lectin_C PF00059.19 001161885.1_39522001_1 - 2.4e-17 63.5 0.0 4.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.16 001161885.1_39522001_1 - 5.6e-09 35.5 30.1 2.7e-08 33.3 30.1 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) V1R PF03402.12 001167497.1_32322001_1 - 1.1e-34 120.1 15.1 1.5e-34 119.7 15.1 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167497.1_32322001_1 - 1.8e-10 40.3 23.2 2.4e-10 39.9 23.2 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167521.1_32322001_1 - 6.5e-33 114.3 17.3 8.8e-33 113.9 17.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167521.1_32322001_1 - 9.6e-17 60.9 27.4 1.1e-16 60.7 27.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001167521.1_32322001_1 - 1.9e-05 23.9 20.9 2.6e-05 23.5 20.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ABC2_membrane_2 PF12679.5 001167521.1_32322001_1 - 0.024 13.8 1.6 0.049 12.8 1.6 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein V1R PF03402.12 001166802.1_32322001_1 - 5.2e-33 114.7 10.3 7.2e-33 114.2 10.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001166802.1_32322001_1 - 1.7e-14 53.5 16.8 2e-14 53.3 16.8 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001166802.1_32322001_1 - 0.044 12.9 17.6 0.11 11.6 17.6 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001253482.1_37622001_1 - 5e-36 124.5 11.0 6.8e-36 124.1 11.0 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253482.1_37622001_1 - 1.4e-15 57.0 13.1 1.8e-15 56.7 13.1 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001253482.1_37622001_1 - 4e-05 22.9 9.3 5.8e-05 22.3 9.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001253487.1_37622001_1 - 3.1e-34 118.7 8.0 4.1e-34 118.3 8.0 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253487.1_37622001_1 - 3.6e-14 52.4 7.0 4.7e-14 52.1 7.0 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Cation_ATPase_C PF00689.19 001253487.1_37622001_1 - 0.36 10.4 6.8 0.022 14.4 1.5 1.6 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus V1R PF03402.12 001253592.1_37622001_1 - 2.8e-34 118.8 13.3 3.3e-34 118.6 13.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253592.1_37622001_1 - 8.2e-08 31.6 14.5 9.2e-08 31.4 14.5 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) GCM PF03615.13 001253592.1_37622001_1 - 0.096 12.4 0.1 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 GCM motif protein V1R PF03402.12 001253597.1_37622001_1 - 4.5e-33 114.9 14.2 6.1e-33 114.4 14.2 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253597.1_37622001_1 - 3.4e-10 39.4 18.8 4.1e-10 39.1 18.8 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001253610.1_37622001_1 - 2.3e-32 112.5 10.6 3e-32 112.1 10.6 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253610.1_37622001_1 - 1.7e-08 33.8 12.9 2.5e-08 33.2 12.9 1.3 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001253653.1_37622001_1 - 7.5e-43 146.9 14.7 1.1e-42 146.3 14.7 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253653.1_37622001_1 - 1.5e-12 47.2 16.4 1.9e-12 46.8 16.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001253653.1_37622001_1 - 0.0002 20.6 11.5 0.00035 19.7 11.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001253660.1_37622001_1 - 1.9e-36 125.9 10.5 2.3e-36 125.7 10.5 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253660.1_37622001_1 - 1.9e-08 33.7 12.7 2.3e-08 33.4 12.7 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001253660.1_37622001_1 - 3.4 6.7 8.2 4.8 6.2 8.1 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001253662.1_37622001_1 - 5.5e-36 124.4 12.9 7e-36 124.1 12.9 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253662.1_37622001_1 - 9.2e-11 41.3 13.3 1.1e-10 41.0 13.3 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF4271 PF14093.4 001253662.1_37622001_1 - 2.7 7.7 16.1 1.1 9.1 0.9 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4271) V1R PF03402.12 001253417.1_37622001_1 - 1.3e-37 129.7 8.1 1.6e-37 129.4 8.1 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253417.1_37622001_1 - 1.7e-12 47.0 6.5 2e-12 46.7 6.5 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) MMPL PF03176.13 001253417.1_37622001_1 - 0.015 14.1 0.6 0.015 14.1 0.6 2.2 3 0 0 3 3 3 0 MMPL family V1R PF03402.12 001253672.1_37622001_1 - 2.7e-40 138.5 11.3 3.6e-40 138.1 11.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253672.1_37622001_1 - 2.3e-12 46.5 13.8 2.9e-12 46.2 13.8 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001253672.1_37622001_1 - 0.013 14.6 10.4 0.019 14.1 10.4 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4079 PF13301.4 001253672.1_37622001_1 - 0.26 11.3 4.8 0.12 12.3 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) V1R PF03402.12 001253420.1_37622001_1 - 2e-39 135.7 12.3 2.9e-39 135.1 12.3 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253420.1_37622001_1 - 7.4e-13 48.1 16.6 9.4e-13 47.8 16.6 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001253420.1_37622001_1 - 0.014 14.5 11.0 0.021 13.9 11.0 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001253427.1_37622001_1 - 1.4e-36 126.4 14.8 1.8e-36 126.0 14.8 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253427.1_37622001_1 - 1.8e-06 27.2 19.0 2.1e-06 27.0 19.0 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001253427.1_37622001_1 - 0.00021 20.5 12.3 0.00028 20.1 12.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001253432.1_37622001_1 - 1.4e-28 100.1 15.7 1.9e-28 99.7 15.7 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253432.1_37622001_1 - 0.0018 17.3 18.9 0.0025 16.8 18.9 1.2 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001253445.1_37622001_1 - 4.2e-47 160.9 14.3 5e-47 160.6 14.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253445.1_37622001_1 - 2.2e-12 46.6 14.0 3e-12 46.1 14.0 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001253498.1_37622001_1 - 6e-39 134.1 12.4 7.9e-39 133.7 12.4 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253498.1_37622001_1 - 4e-12 45.7 15.4 5.1e-12 45.4 15.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001253498.1_37622001_1 - 0.0043 16.2 11.3 0.0058 15.8 11.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001253511.1_37622001_1 - 1.7e-35 122.8 9.3 2.2e-35 122.4 9.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253511.1_37622001_1 - 8.1e-12 44.7 8.4 1.2e-11 44.1 8.4 1.3 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001253511.1_37622001_1 - 3.3e-05 23.1 6.7 3.3e-05 23.1 6.7 1.5 1 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) MDMPI_C PF07398.9 001253511.1_37622001_1 - 0.032 15.0 0.0 0.068 13.9 0.0 1.5 1 0 0 1 1 1 0 MDMPI C-terminal domain WD40 PF00400.30 001253511.1_37622001_1 - 0.033 14.9 0.2 0.089 13.6 0.2 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat MMPL PF03176.13 001253511.1_37622001_1 - 0.036 12.9 0.1 0.036 12.9 0.1 1.9 2 0 0 2 2 2 0 MMPL family V1R PF03402.12 001253516.1_37622001_1 - 1.3e-37 129.7 12.2 1.6e-37 129.4 12.2 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253516.1_37622001_1 - 1e-11 44.4 16.2 1.3e-11 44.1 16.2 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) MMPL PF03176.13 001253516.1_37622001_1 - 0.1 11.3 0.8 0.13 11.0 0.1 1.5 2 0 0 2 2 2 0 MMPL family V1R PF03402.12 001253529.1_37622001_1 - 6e-33 114.4 22.9 8.1e-33 114.0 22.9 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253529.1_37622001_1 - 2.5e-11 43.1 28.6 6.3e-11 41.8 29.0 1.4 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_4 PF13853.4 001168830.1_40422001_1 - 1.9e-108 362.3 20.4 2.3e-108 362.1 20.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001168830.1_40422001_1 - 3.3e-20 72.3 18.3 8.1e-20 71.0 18.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001168830.1_40422001_1 - 4e-09 36.1 16.2 7.6e-09 35.2 16.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001168843.1_40422001_1 - 6.1e-102 341.0 24.6 7.4e-102 340.7 24.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001168843.1_40422001_1 - 4e-12 45.8 23.8 1.4e-11 44.0 23.8 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001168843.1_40422001_1 - 2.3e-08 33.6 17.6 7e-08 32.0 17.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Interferon PF00143.17 001245022.1_22422001_1 - 2.7e-57 193.3 0.2 3e-57 193.1 0.2 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Insulin PF00049.16 001122687.1_37622001_1 - 1.8e-08 35.1 0.1 4.5e-08 33.9 0.1 1.6 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001122687.1_37622001_1 - 0.00031 20.5 6.6 0.059 13.3 1.6 2.2 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type Insulin PF00049.16 001122688.1_37621001_1 - 5.3e-08 33.6 3.4 2.8e-07 31.3 3.4 1.9 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001122688.1_37621001_1 - 0.045 13.6 3.3 4.7 7.2 0.1 2.5 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Cementoin PF10511.7 001173035.1_09929001_2 - 8.7e-103 331.5 393.5 2.9e-06 26.8 2.1 64.5 61 11 8 71 71 71 39 Trappin protein transglutaminase binding domain WAP PF00095.19 001173035.1_09929001_2 - 1.1e-06 28.8 15.8 1.9e-06 28.0 15.8 1.4 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF1474 PF07342.9 001173035.1_09929001_2 - 0.16 12.2 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) DUF3645 PF12359.6 001173035.1_09929001_3 - 0.1 11.9 1.2 1.2e+02 2.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3645) Histone_H2A_C PF16211.3 001265626.1_29621001_3 - 1.3e-20 72.7 1.2 2.1e-20 72.0 1.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.22 001265626.1_29621001_3 - 3.4e-17 63.0 0.0 4.5e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001265626.1_29621001_3 - 0.00014 22.0 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ras PF00071.20 001161870.1_39522001_1 - 3.2e-57 192.5 0.0 3.8e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001161870.1_39522001_1 - 7.3e-30 103.5 0.0 1.1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001161870.1_39522001_1 - 1.6e-11 43.8 0.0 2.1e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001161870.1_39522001_1 - 3.3e-06 27.0 0.0 1.5e-05 25.0 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.14 001161870.1_39522001_1 - 1.8e-05 24.6 0.0 0.011 15.6 0.1 2.4 2 1 0 2 2 2 2 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001161870.1_39522001_1 - 0.00022 20.5 0.0 0.00027 20.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001161870.1_39522001_1 - 0.0078 15.6 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.15 001161870.1_39522001_1 - 0.014 15.0 0.1 0.095 12.3 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.4 001161870.1_39522001_1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.18 001161870.1_39522001_1 - 0.051 12.6 0.7 3.1 6.7 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.7 001161870.1_39522001_1 - 0.067 12.8 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.8 001161870.1_39522001_1 - 0.099 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit p450 PF00067.20 001009743.1_39524001_1 - 6.1e-127 424.0 0.1 7.1e-127 423.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 V1R PF03402.12 001167447.1_09922001_1 - 4.9e-83 278.7 17.0 6.1e-83 278.3 17.0 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167447.1_09922001_1 - 9.4e-05 21.5 22.2 0.00013 21.0 22.2 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001167447.1_09922001_1 - 0.012 14.7 13.1 0.02 14.0 13.1 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001167448.1_09922001_1 - 6.6e-88 294.6 13.4 8.3e-88 294.3 13.4 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167448.1_09922001_1 - 0.00017 20.7 20.1 0.00034 19.7 20.1 1.4 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001167448.1_09922001_1 - 0.0034 16.5 12.0 0.0057 15.8 12.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.6 001167448.1_09922001_1 - 3.3 7.7 6.3 0.96 9.4 1.1 2.8 3 1 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term V1R PF03402.12 001167457.1_09923001_1 - 5.9e-99 330.8 21.7 5.9e-99 330.8 21.7 1.4 2 0 0 2 2 2 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167457.1_09923001_1 - 0.32 9.9 28.5 0.79 8.6 28.5 1.9 1 1 0 1 1 1 0 Taste receptor protein (TAS2R) V1R PF03402.12 001167399.1_09922001_1 - 1.7e-27 96.6 18.8 2.2e-27 96.2 18.8 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167399.1_09922001_1 - 9.8e-10 37.9 24.2 1.2e-09 37.6 24.2 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001167399.1_09922001_1 - 0.0014 17.8 17.5 0.002 17.3 17.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BRI3BP PF14965.4 001167399.1_09922001_1 - 1.5 8.1 5.8 0.51 9.7 0.5 2.7 3 0 0 3 3 3 0 Negative regulator of p53/TP53 V1R PF03402.12 001167400.1_09922001_1 - 1.4e-29 103.4 16.8 1.8e-29 103.0 16.8 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167400.1_09922001_1 - 9.4e-10 37.9 24.6 1.2e-09 37.6 24.6 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167408.1_09922001_1 - 1.8e-32 112.9 11.8 2.5e-32 112.4 11.8 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167408.1_09922001_1 - 2.3e-08 33.4 18.4 2.7e-08 33.1 18.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001167408.1_09922001_1 - 6.3e-07 28.8 11.6 8.6e-07 28.3 11.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001167421.1_09922001_1 - 3.6e-21 75.8 26.8 4.8e-21 75.4 26.8 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167421.1_09922001_1 - 0.0079 15.3 18.3 0.01 15.0 18.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.11 001167421.1_09922001_1 - 0.0093 15.0 31.2 0.017 14.1 31.2 1.4 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) Bac_export_2 PF01312.17 001167421.1_09922001_1 - 8.5 5.3 8.8 2.5 7.1 0.7 2.3 2 1 0 2 2 2 0 FlhB HrpN YscU SpaS Family TGF_beta PF00019.18 037587.1_37923120_1 - 4.9e-24 85.1 0.0 7.4e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain QueC PF06508.11 037587.1_37923120_3 - 6.7 6.0 5.0 1.5 8.1 0.2 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC 7tm_4 PF13853.4 001279642.1_24222001_1 - 2.4e-51 175.0 20.6 2.8e-51 174.8 20.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001279642.1_24222001_1 - 2.6e-24 85.8 24.7 5.8e-24 84.6 24.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001279642.1_24222001_1 - 2e-05 24.0 19.9 3.1e-05 23.3 19.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001279642.1_24222001_1 - 0.00036 19.8 18.1 0.00049 19.4 18.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CPP1-like PF11833.6 001279642.1_24222001_1 - 5.5 6.4 7.9 0.32 10.5 2.0 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like 7tm_1 PF00001.19 001280878.1_29223001_3 - 1e-49 169.1 16.8 1.7e-49 168.3 16.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001280878.1_29223001_3 - 3.5e-06 26.5 17.4 4.7e-06 26.0 17.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srab PF10292.7 001280878.1_29223001_3 - 0.011 14.5 9.6 0.013 14.4 2.2 2.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7tm_4 PF13853.4 001280878.1_29223001_3 - 0.012 15.2 0.4 0.012 15.2 0.4 2.8 2 1 0 3 3 3 0 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001280878.1_29223001_3 - 0.013 14.7 14.7 0.012 14.9 13.6 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF4239 PF14023.4 001280878.1_29223001_3 - 0.73 9.4 7.3 0.1 12.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) LRR_9 PF14580.4 001282023.1_36523001_1 - 4.8e-12 45.6 0.0 2.2e-11 43.4 0.0 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.4 001282023.1_36523001_1 - 3.8e-07 29.7 1.6 3.8e-07 29.7 1.6 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282023.1_36523001_1 - 4.4e-06 26.8 4.4 0.00044 20.4 0.2 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001282023.1_36523001_1 - 5.8 7.7 7.5 1.4e+02 3.4 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat Methyltransf_3 PF01596.15 001282080.1_13422001_1 - 3.8e-11 42.4 0.0 5.2e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001282080.1_13422001_1 - 4.4e-11 43.6 0.0 9e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.17 001282080.1_13422001_1 - 0.015 14.9 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.4 001282080.1_13422001_1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain LRR_9 PF14580.4 001282094.1_20322001_1 - 1.8e-12 47.0 0.1 8.8e-12 44.7 0.0 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.4 001282094.1_20322001_1 - 2.7e-07 30.1 2.4 2.7e-07 30.1 2.4 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282094.1_20322001_1 - 2.6e-06 27.5 7.7 0.0039 17.4 0.6 3.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001282094.1_20322001_1 - 0.16 12.4 5.1 44 5.0 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat Methyltransf_3 PF01596.15 001282111.1_29222001_1 - 1.2e-14 53.9 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001282111.1_29222001_1 - 1.6e-11 45.0 0.0 2.9e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 001282111.1_29222001_1 - 0.0026 17.4 0.0 0.0038 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.4 001282111.1_29222001_1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LRR_9 PF14580.4 001282004.1_35726001_3 - 1.6e-11 43.9 0.0 3.5e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.4 001282004.1_35726001_3 - 1.3e-06 27.9 1.8 1.3e-06 27.9 1.8 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282004.1_35726001_3 - 0.015 15.6 10.5 0.07 13.4 1.4 3.3 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001282124.1_27022001_2 - 2.1e-12 46.8 0.1 1.2e-11 44.3 0.0 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.4 001282124.1_27022001_2 - 4e-07 29.6 1.6 4e-07 29.6 1.6 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282124.1_27022001_2 - 5.6e-06 26.4 7.2 0.007 16.6 0.2 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001282124.1_27022001_2 - 0.75 10.4 6.4 86 4.1 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat Methyltransf_3 PF01596.15 001282125.1_27022001_1 - 9e-16 57.5 0.0 1.2e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001282125.1_27022001_1 - 3.4e-10 40.8 0.0 6.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 001282125.1_27022001_1 - 0.0011 18.7 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.4 001282125.1_27022001_1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.10 001282125.1_27022001_1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_3 PF01596.15 001282009.1_37422001_1 - 4.9e-14 51.9 0.0 6.6e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001282009.1_37422001_1 - 4.4e-13 50.1 0.0 8.9e-13 49.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.17 001282009.1_37422001_1 - 0.0026 17.4 0.0 0.0036 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.4 001282009.1_37422001_1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.15 001282026.1_36522001_1 - 7.1e-13 48.1 0.0 9.5e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001282026.1_36522001_1 - 6e-10 40.0 0.1 1.2e-09 39.0 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.17 001282026.1_36522001_1 - 0.026 14.2 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.4 001282026.1_36522001_1 - 0.054 13.2 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.15 001282030.1_36322001_1 - 3.7e-14 52.3 0.0 4.8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001282030.1_36322001_1 - 1.3e-10 42.1 0.0 2.6e-10 41.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.17 001282030.1_36322001_1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.4 001282030.1_36322001_1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Ald_Xan_dh_C2 PF02738.16 001282264.1_26729001_1 - 2e-181 604.1 0.0 2.6e-181 603.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001282264.1_26729001_1 - 2.1e-42 144.7 0.0 6.5e-42 143.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001282264.1_26729001_1 - 2.7e-31 108.1 2.4 3.4e-31 107.7 1.1 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001282264.1_26729001_1 - 8.1e-30 102.5 0.3 2.7e-29 100.8 0.3 2.0 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001282264.1_26729001_1 - 3.1e-27 94.6 0.0 3.1e-26 91.4 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001282264.1_26729001_1 - 1.2e-06 28.3 1.8 6.9e-06 25.8 0.3 2.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.15 001282264.1_26729001_1 - 0.098 12.5 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 DUF218 domain Ald_Xan_dh_C2 PF02738.16 001302930.1_46729001_1 - 1.3e-159 532.1 0.0 2e-159 531.4 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001302930.1_46729001_1 - 2.6e-45 154.1 0.0 7.3e-45 152.6 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001302930.1_46729001_1 - 1.3e-32 112.3 0.5 2.3e-32 111.5 0.5 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001302930.1_46729001_1 - 2.2e-30 104.3 0.6 5.7e-30 103.0 0.6 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001302930.1_46729001_1 - 8.1e-27 93.3 0.0 5.2e-25 87.5 0.0 2.7 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001302930.1_46729001_1 - 2.5e-08 33.6 0.1 2.5e-08 33.6 0.1 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001302930.1_46729001_1 - 0.0064 16.1 1.7 0.032 13.9 1.7 2.3 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Ald_Xan_dh_C2 PF02738.16 001302930.1_46729001_2 - 1.2e-05 23.9 0.5 1.6e-05 23.5 0.5 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Lys PF00062.18 001290070.1_28322001_3 - 4.2e-54 181.9 7.2 5.6e-54 181.5 7.2 1.1 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family ig PF00047.23 001290068.1_28323001_1 - 6.7e-26 90.2 0.3 5.4e-10 39.2 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001290068.1_28323001_1 - 2.2e-20 72.6 0.2 1.9e-08 34.4 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001290068.1_28323001_1 - 4.5e-20 71.9 0.3 1.7e-06 28.4 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.15 001290068.1_28323001_1 - 2.3e-06 27.6 4.7 4.8 7.2 0.0 5.8 3 3 2 5 5 5 3 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001290068.1_28323001_1 - 0.099 12.6 0.0 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain AAA_18 PF13238.4 001286166.1_37422001_1 - 6.6e-30 104.2 0.0 1e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.4 001286166.1_37422001_1 - 2.3e-07 31.2 0.0 4.5e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.4 001286166.1_37422001_1 - 7.3e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.27 001286166.1_37422001_1 - 0.00018 21.8 0.3 0.00042 20.6 0.1 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 001286166.1_37422001_1 - 0.0013 19.0 0.1 0.0034 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain SKI PF01202.20 001286166.1_37422001_1 - 0.0016 18.4 1.0 0.041 13.9 0.0 2.5 2 1 1 3 3 3 1 Shikimate kinase AAA_33 PF13671.4 001286166.1_37422001_1 - 0.0026 17.8 0.1 0.04 13.9 0.1 2.1 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001286166.1_37422001_1 - 0.0068 15.6 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.4 001286166.1_37422001_1 - 0.0072 16.5 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.13 001286166.1_37422001_1 - 0.01 15.6 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 NTPase ADK PF00406.20 001286166.1_37422001_1 - 0.011 15.7 0.0 0.074 13.0 0.0 2.0 2 0 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.12 001286166.1_37422001_1 - 0.016 15.0 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.15 001286166.1_37422001_1 - 0.033 14.0 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.16 001286166.1_37422001_1 - 0.047 13.3 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase RNA_helicase PF00910.20 001286166.1_37422001_1 - 0.061 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.4 001286166.1_37422001_1 - 0.062 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.17 001286166.1_37422001_1 - 0.093 12.4 1.5 5.9 6.6 0.1 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase ATPase PF06745.11 001286166.1_37422001_1 - 0.13 11.5 0.4 0.45 9.7 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.9 001286166.1_37422001_1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Homeobox PF00046.27 001289851.1_37425001_1 - 1.1e-21 76.2 8.1 2e-21 75.4 8.1 1.5 1 0 0 1 1 1 1 Homeobox domain DUF2209 PF09974.7 001289851.1_37425001_1 - 0.093 12.9 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) MHC_I PF00129.16 001280854.1_47123001_1 - 5.6e-72 240.9 0.9 8e-72 240.4 0.9 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001280854.1_47123001_1 - 3.4e-18 65.8 0.7 7.7e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001280854.1_47123001_1 - 6e-12 45.1 8.4 1.3e-11 44.1 8.4 1.6 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001280854.1_47123001_1 - 7.7e-09 35.9 1.0 2e-08 34.6 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.4 001280854.1_47123001_1 - 9.2e-06 25.8 0.0 2.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001280854.1_47123001_1 - 0.00012 22.1 1.2 0.00023 21.2 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.10 001280854.1_47123001_1 - 0.00032 20.6 0.1 0.00084 19.2 0.1 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain MHC_I_3 PF16497.3 001280854.1_47123001_1 - 0.0024 17.3 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 MHC-I family domain I-set PF07679.14 001280854.1_47123001_1 - 0.0076 16.2 0.4 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain MAP17 PF15807.3 001280854.1_47123001_1 - 0.016 15.3 0.1 0.016 15.3 0.1 2.3 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Orn_Arg_deC_N PF02784.14 001291487.1_47127001_1 - 1.6e-61 207.7 0.0 2.1e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291487.1_47127001_1 - 1.8e-24 85.8 0.0 3.1e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001293731.1_16225001_1 - 9e-73 244.6 0.0 1.1e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293731.1_16225001_1 - 7e-18 64.6 0.0 1.1e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293731.1_16225001_1 - 1.8e-05 24.1 0.0 5.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF4939 PF16297.3 001291117.1_16229001_1 - 1.1e-15 57.3 0.0 2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291117.1_16229001_1 - 3.7e-15 55.9 3.4 5.2e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein KASH_CCD PF14662.4 001291117.1_16229001_1 - 0.00087 19.1 6.0 0.0014 18.4 6.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291117.1_16229001_1 - 0.0058 16.2 0.2 0.014 15.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CCDC106 PF15794.3 001291117.1_16229001_1 - 0.056 13.0 0.5 0.091 12.3 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ZapB PF06005.10 001291117.1_16229001_1 - 0.25 11.7 9.1 0.59 10.5 9.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291117.1_16229001_1 - 0.33 11.5 4.0 0.77 10.3 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Rootletin PF15035.4 001291117.1_16229001_1 - 0.35 10.8 9.2 0.6 10.0 9.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.10 001291117.1_16229001_1 - 0.43 10.9 6.2 0.91 9.8 6.2 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SHE3 PF17078.3 001291117.1_16229001_1 - 0.43 10.1 5.6 0.81 9.2 5.6 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TBPIP PF07106.11 001291117.1_16229001_1 - 0.68 9.5 5.1 1.3 8.6 5.1 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.9 001291117.1_16229001_1 - 1 8.0 6.6 1.7 7.3 6.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.6 001291117.1_16229001_1 - 1.2 9.0 8.5 2.3 8.2 8.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.3 001291117.1_16229001_1 - 1.4 8.8 6.5 3.7 7.5 6.5 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.19 001291117.1_16229001_1 - 1.6 8.7 7.2 3.6 7.6 7.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.13 001291117.1_16229001_1 - 2 8.1 6.0 5 6.8 6.0 1.7 1 0 0 1 1 1 0 Septum formation initiator Uso1_p115_C PF04871.11 001291117.1_16229001_1 - 2.2 8.5 9.7 3.7 7.8 9.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.16 001291117.1_16229001_1 - 2.4 8.3 6.2 5.2 7.2 1.6 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper CAP_N PF01213.17 001291117.1_16229001_1 - 3.3 7.0 5.3 6.4 6.0 5.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SlyX PF04102.10 001291117.1_16229001_1 - 3.4 8.2 5.8 8.9 6.9 5.8 1.6 1 0 0 1 1 1 0 SlyX IncA PF04156.12 001291117.1_16229001_1 - 4.7 6.8 8.8 11 5.6 8.8 1.6 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.6 001291117.1_16229001_1 - 6.4 5.9 6.3 10 5.2 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Asp_protease_2 PF13650.4 001291117.1_16229001_3 - 0.00034 21.1 0.0 0.00056 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291117.1_16229001_3 - 0.0034 17.2 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291117.1_16229001_3 - 0.026 15.0 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease AAA_18 PF13238.4 001286204.1_16222001_1 - 3.6e-29 101.8 0.2 7.7e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.4 001286204.1_16222001_1 - 1.9e-06 28.2 0.1 3.9e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain SKI PF01202.20 001286204.1_16222001_1 - 0.0025 17.8 2.5 0.036 14.1 0.1 2.6 2 1 1 3 3 3 1 Shikimate kinase AAA PF00004.27 001286204.1_16222001_1 - 0.0071 16.6 0.1 0.02 15.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.4 001286204.1_16222001_1 - 0.017 15.1 0.2 0.38 10.8 0.2 2.3 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.4 001286204.1_16222001_1 - 0.026 14.6 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.17 001286204.1_16222001_1 - 0.2 11.4 2.1 8.3 6.1 0.4 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Thymidylate_kin PF02223.15 001286204.1_16222001_1 - 0.2 11.2 1.6 0.63 9.5 0.1 2.0 2 0 0 2 2 2 0 Thymidylate kinase VWD PF00094.23 001281306.1_16229001_3 - 8.7e-128 422.4 9.5 4.9e-39 134.0 0.1 4.5 4 0 0 4 4 4 4 von Willebrand factor type D domain VWA PF00092.26 001281306.1_16229001_3 - 9.9e-78 260.3 0.0 3.9e-30 105.3 0.0 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain C8 PF08742.9 001281306.1_16229001_3 - 4.4e-53 177.5 59.9 8.5e-17 61.2 7.8 8.8 11 0 0 11 11 11 4 C8 domain VWA_N2 PF16164.3 001281306.1_16229001_3 - 2e-35 120.7 3.4 2e-35 120.7 3.4 8.6 8 0 0 8 8 8 1 VWA N-terminal TIL PF01826.15 001281306.1_16229001_3 - 2.1e-27 95.0 108.5 7.4e-12 45.2 14.9 20.2 17 4 2 19 19 19 5 Trypsin Inhibitor like cysteine rich domain VWA_2 PF13519.4 001281306.1_16229001_3 - 1.2e-24 86.9 0.1 1.8e-09 38.1 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWC PF00093.16 001281306.1_16229001_3 - 1.9e-16 59.9 73.3 1.3e-08 34.8 12.1 21.5 16 5 3 19 19 19 7 von Willebrand factor type C domain VWA_3 PF13768.4 001281306.1_16229001_3 - 6.9e-07 29.2 0.1 0.011 15.5 0.1 3.2 3 0 0 3 3 3 2 von Willebrand factor type A domain Pacifastin_I PF05375.11 001281306.1_16229001_3 - 0.00011 21.7 23.1 0.00048 19.7 5.8 12.4 16 0 0 16 16 16 2 Pacifastin inhibitor (LCMII) SMP_LBD PF17047.3 001281306.1_16229001_3 - 0.0059 16.0 0.3 0.4 10.0 0.2 2.3 2 0 0 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain Ald_Xan_dh_C2 PF02738.16 001308994.1_47128001_1 - 2.8e-184 613.5 0.0 3.7e-184 613.1 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001308994.1_47128001_1 - 4.2e-45 153.4 0.0 8.7e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001308994.1_47128001_1 - 5.3e-32 110.3 0.6 1.1e-31 109.4 0.6 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001308994.1_47128001_1 - 1.5e-28 98.4 0.2 3.7e-28 97.1 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001308994.1_47128001_1 - 3.6e-26 91.2 0.0 5.4e-24 84.2 0.0 3.0 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001308994.1_47128001_1 - 9.9e-09 34.9 0.6 9.9e-09 34.9 0.6 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain MHC_I PF00129.16 001309025.1_29723001_2 - 2.7e-92 307.1 1.0 4.1e-92 306.5 1.0 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001309025.1_29723001_2 - 4.4e-18 65.4 0.1 1e-17 64.2 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001309025.1_29723001_2 - 9.1e-15 54.2 8.7 1.7e-14 53.3 8.7 1.5 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001309025.1_29723001_2 - 4.2e-06 27.1 0.5 0.013 16.0 0.0 2.6 1 1 1 2 2 2 2 Immunoglobulin domain MHC_I_3 PF16497.3 001309025.1_29723001_2 - 3.9e-05 23.1 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 MHC-I family domain C2-set_2 PF08205.10 001309025.1_29723001_2 - 0.0014 18.5 0.2 0.0036 17.2 0.2 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001309025.1_29723001_2 - 0.0024 17.9 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain CYYR1 PF10873.6 001309025.1_29723001_2 - 0.038 14.3 0.5 0.068 13.5 0.5 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Podoplanin PF05808.9 001309025.1_29723001_2 - 0.1 12.6 1.2 0.23 11.5 1.2 1.5 1 0 0 1 1 1 0 Podoplanin MHC_II_beta PF00969.17 001308998.1_29722001_1 - 3.8e-37 126.1 1.1 5.9e-37 125.5 1.1 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001308998.1_29722001_1 - 3.4e-25 88.2 0.1 7.1e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001308998.1_29722001_1 - 7.8e-06 26.3 0.1 2.5e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001308998.1_29722001_1 - 0.00036 20.5 0.1 0.00062 19.8 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain DUF202 PF02656.13 001308998.1_29722001_1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) I-set PF07679.14 001308998.1_29722001_1 - 0.12 12.4 0.0 0.35 10.8 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain APOBEC_N PF08210.9 001308530.1_02623001_1 - 2.3e-80 268.6 6.8 6.6e-45 153.1 0.2 2.0 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001308530.1_02623001_1 - 1.2e-60 201.2 0.1 6.9e-30 102.7 0.0 2.6 2 0 0 2 2 2 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001308530.1_02623001_1 - 0.00019 21.1 0.0 0.54 10.0 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Pox_A3L PF05288.9 001308530.1_02623001_1 - 0.02 14.8 0.1 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A3L Protein Toxin-deaminase PF14424.4 001308530.1_02623001_1 - 0.1 12.6 0.1 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases Pox_E10 PF04805.10 001308530.1_02623001_1 - 0.12 12.1 0.2 14 5.5 0.1 2.5 2 0 0 2 2 2 0 E10-like protein conserved region NODP PF07684.10 001308530.1_02623001_1 - 1.1 9.3 2.6 8.2 6.5 0.9 2.2 2 0 0 2 2 2 0 NOTCH protein DUF2162 PF09930.7 001308530.1_02623001_1 - 1.2 8.4 4.0 0.2 10.9 0.3 1.5 2 0 0 2 2 2 0 Predicted transporter (DUF2162) AAA_18 PF13238.4 001286162.1_36523001_1 - 4.9e-31 107.8 0.1 7.9e-31 107.1 0.0 1.4 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.4 001286162.1_36523001_1 - 1e-07 32.3 0.0 2.2e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.4 001286162.1_36523001_1 - 0.00017 21.7 0.0 0.00025 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.27 001286162.1_36523001_1 - 0.00018 21.8 0.2 0.00042 20.6 0.1 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 001286162.1_36523001_1 - 0.0013 19.0 0.0 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SKI PF01202.20 001286162.1_36523001_1 - 0.0014 18.6 1.2 0.032 14.2 0.0 2.5 2 1 1 3 3 3 1 Shikimate kinase ADK PF00406.20 001286162.1_36523001_1 - 0.0029 17.6 0.0 0.045 13.7 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.4 001286162.1_36523001_1 - 0.0037 17.3 0.2 0.06 13.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.4 001286162.1_36523001_1 - 0.0069 16.5 0.1 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.13 001286162.1_36523001_1 - 0.014 15.2 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.10 001286162.1_36523001_1 - 0.015 14.5 0.1 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.12 001286162.1_36523001_1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.20 001286162.1_36523001_1 - 0.026 14.8 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.16 001286162.1_36523001_1 - 0.028 14.0 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.4 001286162.1_36523001_1 - 0.066 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.17 001286162.1_36523001_1 - 0.083 12.6 2.6 6.3 6.5 0.3 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.15 001286162.1_36523001_1 - 0.092 12.6 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.11 001286162.1_36523001_1 - 0.15 11.3 0.6 0.52 9.5 0.0 1.9 2 0 0 2 2 2 0 KaiC 7tm_4 PF13853.4 001287651.1_29524001_2 - 7.4e-95 317.7 28.2 9.4e-95 317.4 28.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001287651.1_29524001_2 - 6.8e-12 45.0 24.8 1.9e-11 43.6 24.8 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001287651.1_29524001_2 - 2.9e-06 26.7 16.8 5.5e-06 25.8 16.3 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TLV_coat PF00429.17 001305389.1_41225001_2 - 3.3e-63 214.1 5.4 8.2e-58 196.3 1.6 2.1 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 001305382.1_31925001_1 - 5.5e-60 203.5 9.0 1.6e-56 192.0 0.2 2.9 3 0 0 3 3 3 2 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 001305239.1_41224001_1 - 2e-61 208.2 2.2 2.2e-56 191.6 0.2 2.3 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) RasGEF PF00617.17 110444.1_32922120_2 - 0.00042 20.4 0.3 0.00085 19.4 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain Glyco_transf_6 PF03414.11 132145.1_35724120_1 - 1.2e-25 89.8 5.1 1.1e-23 83.4 0.1 3.0 3 0 0 3 3 3 3 Glycosyltransferase family 6 Glyco_transf_6 PF03414.11 132145.1_35724120_2 - 1.7e-12 46.6 0.0 2.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_transf_6 PF03414.11 132145.1_35724120_3 - 1.2e-41 142.4 0.2 1.7e-41 141.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_transf_6 PF03414.11 132144.1_43524120_1 - 7.2e-61 205.6 5.2 9.4e-61 205.2 1.4 2.0 1 1 1 2 2 2 2 Glycosyltransferase family 6 Glyco_transf_6 PF03414.11 132144.1_43524120_3 - 5.4e-43 146.8 0.1 7e-43 146.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 Ald_Xan_dh_C2 PF02738.16 001308456.1_39429001_1 - 2.8e-187 623.4 0.0 3.8e-187 622.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001308456.1_39429001_1 - 1.6e-45 154.8 0.0 5e-45 153.2 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001308456.1_39429001_1 - 3.7e-31 107.6 0.2 7.1e-31 106.7 0.2 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001308456.1_39429001_1 - 2.4e-29 101.0 0.5 6e-29 99.7 0.5 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001308456.1_39429001_1 - 6.1e-28 96.9 0.0 2.5e-26 91.7 0.0 2.8 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001308456.1_39429001_1 - 4.9e-09 35.9 0.1 4.9e-09 35.9 0.1 3.2 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001308456.1_39429001_1 - 0.025 14.2 2.1 0.086 12.5 2.1 1.9 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B TLV_coat PF00429.17 001305390.1_31926001_1 - 4.1e-61 207.2 6.6 3.3e-57 194.3 1.5 2.3 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) FGF PF00167.16 001291399.1_28822001_1 - 4.9e-43 146.1 0.1 6.7e-43 145.6 0.1 1.2 1 0 0 1 1 1 1 Fibroblast growth factor PAGK PF15284.4 001291399.1_28822001_2 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phage-encoded virulence factor MHC_I PF00129.16 001292074.1_11723001_2 - 2e-91 304.3 1.0 2.8e-91 303.8 1.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001292074.1_11723001_2 - 4e-17 62.3 0.1 7.8e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001292074.1_11723001_2 - 6.1e-16 57.9 9.7 1.1e-15 57.1 9.7 1.4 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001292074.1_11723001_2 - 1.8e-05 25.2 0.7 0.056 13.9 0.0 2.7 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 001292074.1_11723001_2 - 9.6e-05 22.3 0.1 0.00021 21.2 0.1 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001292074.1_11723001_2 - 0.0099 15.9 0.2 0.045 13.8 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain DUF1049 PF06305.9 001292074.1_11723001_2 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Globin PF00042.20 001290069.1_28321001_1 - 1.8e-21 76.6 0.4 1.8e-21 76.6 0.4 1.5 2 0 0 2 2 2 1 Globin Androgen_recep PF02166.14 001279963.1_46726001_1 - 3e-251 834.2 42.4 3e-251 834.2 42.4 2.0 2 0 0 2 2 2 1 Androgen receptor Hormone_recep PF00104.28 001279963.1_46726001_1 - 2.8e-31 108.6 2.9 4.9e-31 107.8 2.9 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001279963.1_46726001_1 - 4.1e-27 94.3 14.4 8.6e-27 93.3 14.4 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Presenilin PF01080.15 001279963.1_46726001_1 - 1.1 7.9 4.1 1.7 7.2 4.1 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.17 001279963.1_46726001_2 - 4 7.9 16.9 7.2 7.1 16.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4713 PF15831.3 001290584.1_39921001_2 - 9.6e-23 80.3 7.3 1.4e-22 79.7 7.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) EVC2_like PF12297.6 001290584.1_39921001_2 - 0.027 13.0 0.1 0.031 12.8 0.1 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein I-set PF07679.14 001280637.1_52226001_1 - 5e-80 263.5 8.6 1.7e-19 69.5 0.3 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.4 001280637.1_52226001_1 - 4.9e-70 232.0 10.6 8.6e-17 61.4 0.4 5.6 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.23 001280637.1_52226001_1 - 5e-54 180.3 4.8 7.6e-11 41.9 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.4 001280637.1_52226001_1 - 4.6e-45 151.7 4.2 4.9e-09 36.3 0.3 5.3 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.15 001280637.1_52226001_1 - 3e-20 72.3 8.9 0.0026 17.8 0.6 7.7 5 4 0 5 5 5 4 Immunoglobulin V-set domain fn3 PF00041.19 001280637.1_52226001_1 - 1.8e-18 66.5 0.1 4e-12 46.2 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain C1-set PF07654.13 001280637.1_52226001_1 - 1.3e-14 54.3 6.5 0.0027 18.0 0.1 5.6 5 0 0 5 5 5 4 Immunoglobulin C1-set domain Ig_5 PF16681.3 001280637.1_52226001_1 - 2.6e-13 50.1 1.9 0.00017 21.8 0.1 6.0 5 2 0 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.10 001280637.1_52226001_1 - 2.2e-12 46.8 3.1 0.014 15.3 0.1 5.1 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.3 001280637.1_52226001_1 - 5e-11 42.4 0.6 0.2 11.6 0.0 5.1 5 0 0 5 5 5 4 Izumo-like Immunoglobulin domain Ig_4 PF16680.3 001280637.1_52226001_1 - 2.8e-08 33.9 4.6 0.85 9.9 0.1 6.5 5 1 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.13 001280637.1_52226001_1 - 1.7e-05 24.3 2.9 0.27 10.9 0.0 4.0 4 0 0 4 4 4 2 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.6 001280637.1_52226001_1 - 0.00039 20.5 0.5 8.8 6.5 0.0 4.4 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Collagen_bind_2 PF12904.5 001280637.1_52226001_1 - 0.032 14.1 2.3 0.36 10.7 0.1 3.3 3 0 0 3 3 3 0 Putative collagen-binding domain of a collagenase Pur_ac_phosph_N PF16656.3 001280637.1_52226001_1 - 0.25 11.8 3.2 5.3 7.5 0.0 4.0 5 1 0 5 5 5 0 Purple acid Phosphatase, N-terminal domain CD4-extracel PF09191.8 001280654.1_52223001_3 - 2.3e-46 156.5 0.7 1.8e-45 153.6 0.3 2.7 3 0 0 3 3 3 1 CD4, extracellular C2-set PF05790.13 001280654.1_52223001_3 - 1.4e-42 143.6 6.6 4e-22 78.0 0.2 3.5 3 0 0 3 3 3 2 Immunoglobulin C2-set domain ig PF00047.23 001280654.1_52223001_3 - 6.8e-24 83.7 2.9 9.2e-15 54.5 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin domain Ig_3 PF13927.4 001280654.1_52223001_3 - 8.6e-15 55.0 0.9 5.6e-05 23.5 0.0 4.5 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.15 001280654.1_52223001_3 - 9.2e-14 51.4 0.1 1.5e-08 34.6 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.4 001280654.1_52223001_3 - 9.2e-13 48.2 1.0 2.3e-05 24.5 0.0 3.7 2 1 1 3 3 3 2 Immunoglobulin domain Tcell_CD4_C PF12104.6 001280654.1_52223001_3 - 5.5e-12 45.2 9.3 5.5e-12 45.2 9.3 1.8 2 0 0 2 2 1 1 T cell CD4 receptor C terminal region I-set PF07679.14 001280654.1_52223001_3 - 3.3e-11 43.0 0.3 0.00027 20.8 0.0 5.3 3 1 1 4 4 4 2 Immunoglobulin I-set domain Receptor_2B4 PF11465.6 001280654.1_52223001_3 - 8.9e-06 25.7 0.1 0.00021 21.3 0.1 2.6 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 Ig_5 PF16681.3 001280654.1_52223001_3 - 0.00028 21.1 0.0 0.23 11.8 0.0 3.1 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.3 001280654.1_52223001_3 - 0.00083 19.2 0.1 1.3 9.0 0.0 3.3 4 0 0 4 4 3 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.3 001280654.1_52223001_3 - 0.0038 17.4 0.1 7.6 6.8 0.0 3.5 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Sp38 PF07354.10 001280654.1_52223001_3 - 0.0061 15.3 0.0 0.11 11.1 0.0 2.3 2 0 0 2 2 2 1 Zona-pellucida-binding protein (Sp38) E1_DerP2_DerF2 PF02221.13 001279220.1_39621001_1 - 1.7e-14 54.3 0.2 2e-14 54.0 0.2 1.1 1 0 0 1 1 1 1 ML domain IL15 PF02372.13 001292082.1_11722001_3 - 1.4e-53 180.4 3.6 1.4e-53 180.4 3.6 1.4 2 0 0 2 2 2 1 Interleukin 15 Endothelin PF00322.15 001286595.1_40022001_1 - 2.2e-24 84.6 13.8 1.6e-21 75.4 3.6 2.5 2 0 0 2 2 2 2 Endothelin family HECT PF00632.23 001280106.1_35729001_3 - 9.6e-99 330.6 0.3 1.3e-98 330.1 0.3 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.24 001280106.1_35729001_3 - 1.9e-47 158.7 31.1 7.4e-13 48.1 4.2 4.7 4 0 0 4 4 4 4 WW domain Acetyltransf_1 PF00583.23 001280875.1_36322001_1 - 1.4e-13 51.0 0.0 1.7e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.5 001280875.1_36322001_1 - 2.9e-08 33.6 0.0 4.1e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 001280875.1_36322001_1 - 2.4e-05 24.6 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain IL10 PF00726.15 001281318.1_16222001_1 - 4.9e-79 263.6 0.1 5.7e-79 263.4 0.1 1.0 1 0 0 1 1 1 1 Interleukin 10 Hist_deacetyl PF00850.17 001286591.1_40023001_1 - 4.9e-83 279.0 0.1 8.5e-83 278.2 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Transferrin PF00405.15 001308674.1_35725001_1 - 1.7e-265 878.6 11.4 9.5e-174 577.0 0.3 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.5 001308674.1_35725001_1 - 3e-14 53.1 0.0 7.5e-07 28.8 0.0 2.8 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.18 001308674.1_35725001_1 - 0.0093 15.3 0.0 1.6 8.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Leptin PF02024.13 001302928.1_46222001_1 - 1.2e-69 232.6 1.7 1.3e-69 232.4 1.7 1.0 1 0 0 1 1 1 1 Leptin Ald_Xan_dh_C2 PF02738.16 001302929.1_46728001_1 - 4.6e-187 622.7 0.1 5.7e-187 622.4 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001302929.1_46728001_1 - 1.1e-44 152.1 0.0 2.5e-44 150.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001302929.1_46728001_1 - 4.2e-32 110.6 0.0 8.9e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001302929.1_46728001_1 - 6.2e-31 106.0 0.8 1.8e-30 104.6 0.8 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001302929.1_46728001_1 - 1.3e-26 92.6 0.0 3.7e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001302929.1_46728001_1 - 5.1e-09 35.8 0.1 5.1e-09 35.8 0.1 3.1 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain ACP_syn_III_C PF08541.8 001302929.1_46728001_1 - 0.1 12.6 0.0 0.58 10.2 0.0 2.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ldh_1_N PF00056.21 001310204.1_33424001_3 - 5.7e-51 172.2 0.7 8.1e-51 171.7 0.7 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001310204.1_33424001_3 - 8.6e-24 84.2 0.0 1.7e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Pyr_redox_2 PF07992.12 001310204.1_33424001_3 - 0.02 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_4 PF02056.14 001310204.1_33424001_3 - 0.025 14.0 0.7 0.075 12.5 0.0 2.0 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase TNF PF00229.16 001310183.1_33422001_1 - 2.3e-39 134.1 0.0 3.2e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family KAR9 PF08580.8 001310183.1_33422001_2 - 1.1 7.6 5.6 1.4 7.2 5.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 LRR_9 PF14580.4 001282036.1_33423001_2 - 1e-12 47.8 0.0 3.8e-12 45.9 0.0 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.4 001282036.1_33423001_2 - 4.1e-07 29.5 1.6 4.1e-07 29.5 1.6 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282036.1_33423001_2 - 1.5e-05 25.1 5.1 0.00048 20.3 0.2 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001282036.1_33423001_2 - 6 7.6 7.2 1.5e+02 3.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat 7tm_1 PF00001.19 001310182.1_33425001_3 - 2.2e-29 102.4 22.2 3.4e-29 101.8 22.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.4 001310182.1_33425001_3 - 6.6e-17 60.9 4.3 0.00035 20.2 0.7 4.8 3 2 1 4 4 4 4 Leucine rich repeat LRR_5 PF13306.4 001310182.1_33425001_3 - 9e-13 48.2 13.1 1.9e-07 31.0 1.6 3.2 1 1 2 3 3 3 2 Leucine rich repeats (6 copies) LRR_4 PF12799.5 001310182.1_33425001_3 - 0.019 15.2 4.5 1.5 9.2 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001282008.1_37423001_2 - 1e-12 47.8 0.0 3.2e-12 46.1 0.0 1.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.4 001282008.1_37423001_2 - 3.6e-07 29.7 1.6 3.6e-07 29.7 1.6 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282008.1_37423001_2 - 3.4e-06 27.1 4.2 0.00042 20.5 0.2 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001282008.1_37423001_2 - 8.3 7.2 7.4 1.4e+02 3.5 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat RNase_H PF00075.22 001285515.1_37422001_1 - 2.5e-45 154.1 0.0 4e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285515.1_37422001_1 - 5e-19 68.2 1.3 9.7e-19 67.3 1.3 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285515.1_37422001_1 - 0.00054 19.5 0.0 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like Orn_Arg_deC_N PF02784.14 001291512.1_37429001_1 - 1.8e-62 210.9 0.1 2.3e-62 210.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291512.1_37429001_1 - 4.7e-24 84.5 0.0 8.3e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301739.1_37429001_2 - 1.7e-62 211.0 0.1 2.2e-62 210.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301739.1_37429001_2 - 4.4e-24 84.6 0.0 7.9e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PTEN_C2 PF10409.7 001309477.1_37424001_1 - 5.4e-47 158.8 2.5 8.1e-47 158.2 2.5 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.18 001309477.1_37424001_1 - 6.5e-08 32.3 0.0 3e-07 30.2 0.0 2.0 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001309477.1_37424001_1 - 0.00017 21.1 0.0 0.00043 19.8 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.4 001309477.1_37424001_1 - 0.0031 17.4 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.4 001309477.1_37424001_1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF3256 PF11644.6 001309477.1_37424001_1 - 0.02 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Orn_Arg_deC_N PF02784.14 001293724.1_37425001_3 - 7.6e-71 238.3 0.0 9.4e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293724.1_37425001_3 - 3.2e-18 65.7 0.0 5.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293724.1_37425001_3 - 7.6e-05 22.1 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SLAM PF06214.9 001279809.1_37423001_1 - 4.1e-63 210.8 0.1 7e-63 210.1 0.1 1.4 1 0 0 1 1 1 1 Signaling lymphocytic activation molecule (SLAM) protein Ig_3 PF13927.4 001279809.1_37423001_1 - 4.9e-05 23.7 0.3 0.011 16.2 0.2 2.6 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001279809.1_37423001_1 - 0.0037 17.3 0.1 0.037 14.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 001279809.1_37423001_1 - 0.0075 16.3 0.1 0.069 13.2 0.0 2.5 3 1 0 3 3 3 1 Immunoglobulin V-set domain Syndecan PF01034.18 001279809.1_37423001_1 - 0.051 13.4 0.3 2 8.3 0.2 2.4 2 0 0 2 2 2 0 Syndecan domain Arm PF00514.21 001159312.1_49824001_1 - 1.5e-42 142.3 21.4 1e-09 38.0 0.0 8.4 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT PF02985.20 001159312.1_49824001_1 - 9.1e-17 59.6 6.9 0.017 15.2 0.0 7.5 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.4 001159312.1_49824001_1 - 4.5e-15 55.7 10.7 0.00021 21.5 0.5 5.5 3 2 1 5 5 5 4 HEAT repeats Cnd1 PF12717.5 001159312.1_49824001_1 - 1e-14 54.7 1.1 0.0032 17.4 0.0 4.8 1 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.4 001159312.1_49824001_1 - 6.9e-12 45.4 16.6 0.001 19.4 0.0 6.3 6 1 1 7 7 6 3 HEAT-like repeat CHASE6_C PF17150.2 001159312.1_49824001_1 - 1.1e-07 32.3 2.5 8 7.1 0.0 7.0 7 1 0 7 7 7 1 C-terminal domain of two-partite extracellular sensor domain DNA_alkylation PF08713.9 001159312.1_49824001_1 - 5.2e-07 29.5 0.1 0.89 9.1 0.0 4.4 2 1 0 4 4 4 2 DNA alkylation repair enzyme Adaptin_N PF01602.18 001159312.1_49824001_1 - 2.4e-05 23.0 5.5 0.019 13.4 1.2 3.7 1 1 1 3 3 3 2 Adaptin N terminal region Proteasom_PSMB PF10508.7 001159312.1_49824001_1 - 5.4e-05 21.8 6.2 0.0014 17.1 0.7 3.3 1 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.7 001159312.1_49824001_1 - 0.00011 22.1 1.6 0.54 10.2 0.1 4.8 3 2 3 6 6 6 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.6 001159312.1_49824001_1 - 0.0013 18.3 0.3 2.6 7.4 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal V-ATPase_H_C PF11698.6 001159312.1_49824001_1 - 0.0089 16.0 1.1 1.3 9.0 0.1 3.8 3 1 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.14 001159312.1_49824001_1 - 0.016 15.7 14.3 0.4 11.4 0.2 5.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.7 001159312.1_49824001_1 - 0.018 15.0 1.0 0.055 13.5 0.3 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.5 001159312.1_49824001_1 - 0.094 13.2 0.2 1.5 9.3 0.1 2.9 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Rcd1 PF04078.11 001159312.1_49824001_1 - 0.11 11.7 1.4 0.32 10.1 0.2 2.3 3 1 0 3 3 3 0 Cell differentiation family, Rcd1-like DUF3361 PF11841.6 001159312.1_49824001_1 - 0.19 11.5 2.2 1.1 9.0 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) DUF3731 PF12531.6 001159312.1_49824001_1 - 0.32 10.6 5.0 4 7.0 0.1 3.5 3 1 0 3 3 3 0 DNA-K related protein XPC-binding PF09280.9 001159312.1_49824001_1 - 0.39 10.4 4.5 60 3.4 0.0 4.9 5 0 0 5 5 5 0 XPC-binding domain RTTN_N PF14726.4 001159312.1_49824001_1 - 0.41 11.4 2.7 8.6 7.2 0.2 3.3 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning rRNA_processing PF08524.9 001243859.1_49822001_3 - 5.8e-12 45.7 25.0 5.8e-12 45.7 25.0 2.2 2 0 0 2 2 2 1 rRNA processing Peptidase_M10 PF00413.22 001099938.1_49823001_1 - 3.2e-60 202.4 0.1 5.3e-60 201.7 0.1 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.17 001099938.1_49823001_1 - 4.1e-41 138.5 20.0 1.9e-16 59.6 1.2 4.5 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.16 001099938.1_49823001_1 - 2.8e-13 49.7 0.1 4.9e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.22 001099938.1_49823001_1 - 0.0034 16.9 0.1 1.3 8.4 0.1 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Metallopep PF12044.6 001099938.1_49823001_1 - 0.014 13.9 0.1 0.022 13.2 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.7 001099938.1_49823001_1 - 0.024 13.5 0.4 0.038 12.8 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.4 001099938.1_49823001_1 - 0.035 14.5 0.1 0.06 13.7 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.9 001099938.1_49823001_1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_5 PF13688.4 001099938.1_49823001_1 - 0.15 12.1 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Uteroglobin PF01099.15 001123161.1_49821001_1 - 8.1e-20 70.7 1.7 9.8e-20 70.4 1.7 1.1 1 0 0 1 1 1 1 Uteroglobin family GDP_Man_Dehyd PF16363.3 001244774.1_49824001_3 - 1e-55 189.3 0.0 3.8e-55 187.4 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.19 001244774.1_49824001_3 - 5.8e-50 169.9 0.0 8e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UXS1_N PF11803.6 001244774.1_49824001_3 - 1.1e-34 118.5 0.5 2.4e-34 117.4 0.0 1.9 2 0 0 2 2 2 1 UDP-glucuronate decarboxylase N-terminal NAD_binding_4 PF07993.10 001244774.1_49824001_3 - 2.8e-10 39.7 0.0 2.4e-06 26.8 0.0 2.5 2 1 0 3 3 3 2 Male sterility protein RmlD_sub_bind PF04321.15 001244774.1_49824001_3 - 5.5e-10 38.7 0.0 7.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.17 001244774.1_49824001_3 - 9.2e-08 31.3 0.0 1.8e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.13 001244774.1_49824001_3 - 1.2e-07 31.1 0.3 0.00037 19.6 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein PDZ PF00595.22 001206404.1_49829001_2 - 3.3e-44 149.0 6.9 5e-15 55.5 0.2 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001206404.1_49829001_2 - 1.4e-15 57.2 1.5 0.00094 19.3 0.0 3.4 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.19 001206404.1_49829001_2 - 1.8e-11 43.9 0.0 4.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.15 001206404.1_49829001_2 - 4.3e-08 32.6 0.2 3.2e-07 29.8 0.0 2.6 4 0 0 4 4 4 1 Variant SH3 domain SH3_1 PF00018.26 001206404.1_49829001_2 - 0.00074 18.9 0.0 0.0056 16.1 0.0 2.5 2 0 0 2 2 2 1 SH3 domain EF-hand_6 PF13405.4 001244975.1_49823001_3 - 3.6e-18 63.8 0.4 0.0011 18.5 0.0 5.0 5 1 1 6 6 6 4 EF-hand domain EF-hand_7 PF13499.4 001244975.1_49823001_3 - 8.2e-18 64.5 0.1 3.3e-08 33.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001244975.1_49823001_3 - 1.1e-16 58.9 0.1 0.00033 19.9 0.0 5.1 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.4 001244975.1_49823001_3 - 1.6e-08 33.5 0.7 0.14 11.6 0.1 4.4 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.4 001244975.1_49823001_3 - 2.8e-08 33.3 0.8 0.00028 20.5 0.0 3.9 3 2 0 4 4 4 2 EF-hand domain pair RSN1_7TM PF02714.13 001243189.1_49827001_3 - 3.5e-54 183.9 19.7 8.5e-54 182.6 19.7 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.4 001243189.1_49827001_3 - 4.6e-42 144.1 0.1 6.5e-42 143.6 0.1 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.4 001243189.1_49827001_3 - 2.5e-20 72.7 1.8 2.5e-20 72.7 1.8 4.7 5 1 1 6 6 6 2 Late exocytosis, associated with Golgi transport RRM_1 PF00076.20 001243189.1_49827001_3 - 0.0014 18.2 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDK PF00334.17 045137.1_49822120_2 - 1.5e-54 183.5 0.0 1.9e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ODC_AZ PF02100.15 125342.1_49823120_2 - 4.2e-20 71.7 0.0 7.4e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme CD36 PF01130.19 001285580.1_09024001_1 - 6.9e-145 483.0 1.0 8.1e-145 482.8 1.0 1.0 1 0 0 1 1 1 1 CD36 family LRR_8 PF13855.4 001285613.1_09022001_1 - 5.8e-19 67.5 9.1 1.2e-09 37.7 0.1 4.1 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 001285613.1_09022001_1 - 9.8e-10 38.4 15.2 3.6e-05 23.9 2.0 4.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001285613.1_09022001_1 - 8.3e-06 25.4 12.2 1.2 9.7 0.0 5.8 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_5 PF13306.4 001285613.1_09022001_1 - 0.00042 20.1 1.5 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_6 PF13516.4 001285613.1_09022001_1 - 0.0046 16.8 1.5 6.8 6.9 0.0 4.2 4 0 0 4 4 4 1 Leucine Rich repeat LRR_9 PF14580.4 001285613.1_09022001_1 - 0.036 13.4 2.1 0.17 11.2 0.1 2.1 1 1 2 3 3 3 0 Leucine-rich repeat DUF1409 PF07197.10 001285613.1_09022001_1 - 0.095 12.5 0.1 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) p450 PF00067.20 001286090.1_09024001_1 - 6.3e-130 433.9 0.0 7.7e-130 433.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Replic_Relax PF13814.4 001286090.1_09024001_1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Replication-relaxation YjcB PF15940.3 001286090.1_09024001_2 - 0.024 14.7 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function Perilipin PF03036.14 001285596.1_09023001_1 - 9.3e-164 545.0 11.8 1.1e-163 544.8 11.8 1.0 1 0 0 1 1 1 1 Perilipin family DUF4618 PF15397.4 001285596.1_09023001_1 - 0.048 13.0 3.2 0.071 12.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF1664 PF07889.10 001285596.1_09023001_1 - 0.25 11.2 4.5 11 5.9 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) V-SNARE_C PF12352.6 001285596.1_09023001_1 - 0.34 11.1 3.5 0.38 11.0 0.9 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Apolipoprotein PF01442.16 001285596.1_09023001_1 - 0.34 10.7 4.7 1.6 8.5 0.1 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain HSP9_HSP12 PF04119.10 001285596.1_09023001_1 - 0.36 11.1 4.5 4.9 7.5 0.0 3.6 3 1 0 3 3 3 0 Heat shock protein 9/12 Snapin_Pallidin PF14712.4 001285596.1_09023001_1 - 1 9.7 6.1 1.5 9.1 0.7 3.3 3 1 0 3 3 3 0 Snapin/Pallidin Laminin_II PF06009.10 001285596.1_09023001_1 - 1.2 9.0 6.1 3.6 7.5 0.1 3.4 3 1 1 4 4 4 0 Laminin Domain II Nup54 PF13874.4 001285596.1_09023001_1 - 4.7 7.2 6.7 47 3.9 6.3 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.10 001285596.1_09023001_1 - 7.2 6.5 10.2 2.6 8.0 0.4 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reticulon PF02453.15 001145178.1_39522001_1 - 2.4e-47 160.6 6.8 3.2e-47 160.3 6.8 1.1 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.10 001145178.1_39522001_1 - 0.01 15.1 1.8 0.016 14.5 1.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF4736 PF15883.3 001145178.1_39522001_1 - 0.13 11.8 0.2 0.13 11.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Pkinase_Tyr PF07714.15 001165890.1_39524001_1 - 1.4e-60 204.7 0.0 1.8e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001165890.1_39524001_1 - 1.9e-55 188.0 0.0 2.7e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.13 001165890.1_39524001_1 - 4.1e-24 84.3 0.1 7.1e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.20 001165890.1_39524001_1 - 1.2e-10 41.0 10.2 2e-10 40.2 10.2 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.4 001165890.1_39524001_1 - 4.8e-08 32.5 0.0 7.3e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.9 001165890.1_39524001_1 - 0.0021 18.2 4.7 0.0056 16.8 4.7 1.7 1 0 0 1 1 1 1 RING-like domain APH PF01636.21 001165890.1_39524001_1 - 0.0071 16.2 0.5 0.14 11.9 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family TUG-UBL1 PF11470.6 001165890.1_39524001_1 - 0.038 14.1 0.1 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 TUG ubiquitin-like domain Kdo PF06293.12 001165890.1_39524001_1 - 0.087 12.0 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.4 001165890.1_39524001_1 - 5.6 7.2 8.6 14 5.9 8.6 1.7 1 0 0 1 1 1 0 Ring finger domain Lectin_C PF00059.19 001038014.1_39522001_2 - 5.6e-18 65.5 0.0 7.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Ald_Xan_dh_C2 PF02738.16 001279815.1_36229001_1 - 2.8e-184 613.5 0.0 3.7e-184 613.1 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001279815.1_36229001_1 - 6.2e-43 146.3 0.0 1.3e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.18 001279815.1_36229001_1 - 3.3e-31 106.9 0.3 7.7e-31 105.7 0.3 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.20 001279815.1_36229001_1 - 1.5e-30 105.7 0.5 2.9e-30 104.7 0.5 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001279815.1_36229001_1 - 2.1e-29 101.6 0.0 5.5e-29 100.2 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001279815.1_36229001_1 - 8.8e-10 38.3 0.6 4.4e-09 36.1 0.0 2.6 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain RhoGAP PF00620.25 001279815.1_36229001_1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain LRR_8 PF13855.4 001282160.1_36222001_2 - 4e-08 32.8 1.4 4e-08 32.8 1.4 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282160.1_36222001_2 - 4.3e-06 26.8 8.8 0.0037 17.5 0.6 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001282160.1_36222001_2 - 1.4e-05 24.5 0.2 0.00011 21.6 0.0 2.0 1 1 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.31 001282160.1_36222001_2 - 0.19 12.2 5.4 60 4.6 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat Orn_Arg_deC_N PF02784.14 001291519.1_36229001_3 - 4.5e-62 209.6 0.0 5.8e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291519.1_36229001_3 - 2.2e-23 82.3 0.0 3.8e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301747.1_36229001_2 - 4.3e-62 209.6 0.0 5.5e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301747.1_36229001_2 - 2.1e-23 82.4 0.0 3.6e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Lectin_C PF00059.19 001309938.1_31522001_1 - 3.3e-16 59.8 2.4 3.3e-16 59.8 2.4 1.8 2 0 0 2 2 2 1 Lectin C-type domain Ly49 PF08391.8 001309938.1_31522001_1 - 5.4 7.3 12.4 64 3.8 12.4 2.5 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region zf-C3HC4_4 PF15227.4 001309943.1_31523001_1 - 4.9e-11 42.5 9.3 4.9e-11 42.5 9.3 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.4 001309943.1_31523001_1 - 1.4e-10 40.9 4.0 1.4e-10 40.9 4.0 2.7 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001309943.1_31523001_1 - 2.7e-09 36.6 9.1 1.2e-08 34.5 9.1 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SPRY PF00622.26 001309943.1_31523001_1 - 9.4e-09 35.3 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.22 001309943.1_31523001_1 - 1.1e-07 31.8 6.1 1.1e-07 31.8 6.1 3.2 3 1 0 3 3 3 2 B-box zinc finger zf-RING_2 PF13639.4 001309943.1_31523001_1 - 3.3e-07 30.3 8.5 3.3e-07 30.3 8.5 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.4 001309943.1_31523001_1 - 7.4e-07 28.8 6.2 7.4e-07 28.8 6.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001309943.1_31523001_1 - 1.1e-06 28.3 8.9 1.1e-06 28.3 8.9 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001309943.1_31523001_1 - 4.7e-06 26.3 8.0 4.7e-06 26.3 8.0 2.9 2 1 1 3 3 3 1 zinc-RING finger domain U-box PF04564.13 001309943.1_31523001_1 - 0.0025 17.8 0.0 0.011 15.8 0.0 2.1 1 1 0 1 1 1 1 U-box domain zf-RING_10 PF16685.3 001309943.1_31523001_1 - 0.0041 17.1 4.3 0.0041 17.1 4.3 2.9 2 1 1 3 3 3 1 zinc RING finger of MSL2 zf-Nse PF11789.6 001309943.1_31523001_1 - 0.0055 16.4 5.0 0.021 14.5 5.0 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TF_AP-2 PF03299.12 001309943.1_31523001_1 - 0.059 13.2 3.1 0.11 12.4 3.1 1.5 1 0 0 1 1 1 0 Transcription factor AP-2 zf-RING_6 PF14835.4 001309943.1_31523001_1 - 0.14 11.9 9.0 0.044 13.5 4.1 2.6 2 1 0 2 2 2 0 zf-RING of BARD1-type protein AAA_9 PF12781.5 001309943.1_31523001_1 - 0.23 10.4 11.5 0.32 9.9 0.3 2.3 1 1 1 2 2 2 0 ATP-binding dynein motor region D5 DUF3510 PF12022.6 001309943.1_31523001_1 - 0.38 11.0 4.5 1.2 9.4 4.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) Dynein_light PF01221.16 001309943.1_31523001_1 - 0.55 10.4 6.8 1.9 8.7 0.1 3.0 2 0 0 2 2 2 0 Dynein light chain type 1 GAGA PF09237.9 001309943.1_31523001_1 - 0.63 9.8 5.7 5.2 6.8 2.3 2.7 2 0 0 2 2 2 0 GAGA factor zf-RING_4 PF14570.4 001309943.1_31523001_1 - 3.8 7.2 12.2 0.039 13.5 2.2 2.7 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain Vps36-NZF-N PF16988.3 001309943.1_31523001_1 - 6 6.2 7.9 3.5 7.0 2.3 3.2 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Orn_Arg_deC_N PF02784.14 001291639.1_11328001_2 - 8.3e-62 208.7 0.1 1.1e-61 208.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291639.1_11328001_2 - 1.3e-22 79.8 0.0 2.4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Toxin_11 PF07473.9 001291251.1_11329001_1 - 0.58 10.2 4.2 6.7 6.8 4.2 2.9 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species Asp_protease_2 PF13650.4 001291251.1_11329001_2 - 0.0029 18.1 0.0 0.0046 17.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291251.1_11329001_2 - 0.013 15.4 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291251.1_11329001_2 - 0.18 12.2 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291251.1_11329001_3 - 9.7e-14 51.3 1.3 2.4e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291251.1_11329001_3 - 2.2e-13 49.9 0.0 3.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291251.1_11329001_3 - 0.00032 20.5 1.4 0.00054 19.7 1.4 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291251.1_11329001_3 - 0.0032 17.0 2.9 0.0033 17.0 0.2 2.2 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291251.1_11329001_3 - 0.004 16.9 0.1 0.0065 16.2 0.1 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 SlyX PF04102.10 001291251.1_11329001_3 - 0.032 14.7 3.9 0.091 13.3 3.9 1.7 1 0 0 1 1 1 0 SlyX bZIP_1 PF00170.19 001291251.1_11329001_3 - 0.075 13.0 1.7 0.22 11.5 1.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor Rootletin PF15035.4 001291251.1_11329001_3 - 0.1 12.5 3.9 0.2 11.6 3.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.17 001291251.1_11329001_3 - 0.2 9.4 1.8 0.26 9.0 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GIT_CC PF16559.3 001291251.1_11329001_3 - 0.24 11.3 5.2 0.44 10.5 5.2 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.10 001291251.1_11329001_3 - 0.61 10.4 6.8 1.5 9.2 6.8 1.5 1 0 0 1 1 1 0 Cell division protein ZapB zf-CCHC PF00098.21 001291251.1_11329001_3 - 0.73 9.9 7.2 0.25 11.4 2.2 2.9 2 0 0 2 2 2 0 Zinc knuckle CENP-H PF05837.10 001291251.1_11329001_3 - 1.1 9.6 4.4 2.2 8.6 4.4 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.13 001291251.1_11329001_3 - 1.1 8.9 3.5 3 7.5 3.5 1.7 1 0 0 1 1 1 0 Septum formation initiator zf-CCHC_2 PF13696.4 001291251.1_11329001_3 - 2.1 8.1 10.6 0.72 9.6 0.7 3.1 2 0 0 2 2 2 0 Zinc knuckle IncA PF04156.12 001291251.1_11329001_3 - 2.2 7.9 4.6 4.9 6.8 4.6 1.5 1 0 0 1 1 1 0 IncA protein Orn_Arg_deC_N PF02784.14 001293750.2_11325001_2 - 6.3e-69 232.0 0.0 7.8e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293750.2_11325001_2 - 2.8e-19 69.1 0.0 4.5e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291632.1_26729001_1 - 4.3e-62 209.6 0.1 5.4e-62 209.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291632.1_26729001_1 - 2.1e-24 85.6 0.0 3.7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001293747.1_26725001_1 - 2e-72 243.5 0.0 2.5e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293747.1_26725001_1 - 1.9e-16 60.0 0.0 3.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293747.1_26725001_1 - 4.6e-05 22.8 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001301789.1_26729001_3 - 4.5e-62 209.6 0.1 5.6e-62 209.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301789.1_26729001_3 - 2.2e-24 85.6 0.0 3.9e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AAA_18 PF13238.4 001286241.1_26722001_2 - 1.8e-30 106.0 0.0 3e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.4 001286241.1_26722001_2 - 4e-06 27.2 0.0 8.2e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.27 001286241.1_26722001_2 - 6.7e-05 23.2 0.0 0.00026 21.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.4 001286241.1_26722001_2 - 0.00033 20.8 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.20 001286241.1_26722001_2 - 0.00074 19.5 1.7 0.022 14.8 0.0 2.7 2 1 1 3 3 3 1 Shikimate kinase AAA_16 PF13191.4 001286241.1_26722001_2 - 0.002 18.4 0.2 0.004 17.4 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 001286241.1_26722001_2 - 0.0046 17.1 0.0 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.4 001286241.1_26722001_2 - 0.0084 16.1 0.1 0.047 13.7 0.1 2.0 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.13 001286241.1_26722001_2 - 0.011 15.5 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.10 001286241.1_26722001_2 - 0.013 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.12 001286241.1_26722001_2 - 0.018 14.9 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.4 001286241.1_26722001_2 - 0.058 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001286241.1_26722001_2 - 0.072 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.15 001286241.1_26722001_2 - 0.075 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ADK PF00406.20 001286241.1_26722001_2 - 0.077 13.0 0.0 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Adenylate kinase dNK PF01712.17 001286241.1_26722001_2 - 0.12 12.1 2.3 6.7 6.4 0.1 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin PF02224.16 001286241.1_26722001_2 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase ATPase PF06745.11 001286241.1_26722001_2 - 0.16 11.2 0.6 0.46 9.6 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.9 001286241.1_26722001_2 - 0.16 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ald_Xan_dh_C2 PF02738.16 001282248.1_26728001_1 - 4.2e-186 619.5 0.0 5.7e-186 619.1 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001282248.1_26728001_1 - 3.1e-46 157.1 0.0 7.5e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001282248.1_26728001_1 - 2.4e-31 108.2 0.3 4.7e-31 107.3 0.3 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001282248.1_26728001_1 - 1.2e-29 101.9 0.2 3e-29 100.7 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001282248.1_26728001_1 - 8.7e-28 96.4 0.0 6.2e-26 90.4 0.0 3.3 4 0 0 4 4 4 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001282248.1_26728001_1 - 4.1e-09 36.1 2.0 6.5e-09 35.5 0.2 2.5 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001282248.1_26728001_1 - 0.23 11.2 5.6 0.035 13.8 0.8 2.2 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Asp_protease_2 PF13650.4 001291232.1_26729001_2 - 0.00032 21.2 0.0 0.00053 20.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291232.1_26729001_2 - 0.0083 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291232.1_26729001_2 - 0.047 14.1 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291232.1_26729001_3 - 4.6e-15 55.3 0.0 8.6e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291232.1_26729001_3 - 6.3e-15 55.1 1.9 1.7e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.4 001291232.1_26729001_3 - 0.0018 17.8 0.2 0.0043 16.6 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001291232.1_26729001_3 - 0.0036 17.0 3.8 0.006 16.3 3.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc29 PF17082.3 001291232.1_26729001_3 - 0.038 13.7 0.2 0.063 13.0 0.2 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Rootletin PF15035.4 001291232.1_26729001_3 - 0.11 12.4 6.6 0.2 11.5 6.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.10 001291232.1_26729001_3 - 0.15 12.4 9.0 0.33 11.3 9.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF1664 PF07889.10 001291232.1_26729001_3 - 0.28 11.1 0.8 0.56 10.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.12 001291232.1_26729001_3 - 0.3 10.7 1.6 0.61 9.7 1.6 1.4 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.11 001291232.1_26729001_3 - 0.44 11.1 2.8 1.1 9.8 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.19 001291232.1_26729001_3 - 0.53 10.3 5.6 1.4 8.9 4.4 2.0 1 1 0 1 1 1 0 bZIP transcription factor CCDC106 PF15794.3 001291232.1_26729001_3 - 0.62 9.6 3.0 1.1 8.8 3.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001291232.1_26729001_3 - 0.8 10.0 4.3 1.9 8.8 4.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.13 001291232.1_26729001_3 - 0.92 9.2 4.5 2.4 7.9 4.5 1.6 1 0 0 1 1 1 0 Septum formation initiator SHE3 PF17078.3 001291232.1_26729001_3 - 1.1 8.8 5.6 0.65 9.5 3.9 1.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 SlyX PF04102.10 001291232.1_26729001_3 - 1.8 9.1 4.5 4.6 7.8 4.5 1.6 1 0 0 1 1 1 0 SlyX GIT_CC PF16559.3 001291232.1_26729001_3 - 4.1 7.4 7.3 14 5.7 7.3 1.9 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Asp_protease_2 PF13650.4 001291244.1_31929001_1 - 0.0023 18.4 0.0 0.0035 17.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291244.1_31929001_1 - 0.0024 17.7 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291244.1_31929001_1 - 0.038 14.4 0.0 0.055 13.9 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291244.1_31929001_2 - 7.1e-18 64.4 0.0 1.3e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291244.1_31929001_2 - 3e-17 62.6 0.3 5.6e-17 61.7 0.3 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_5 PF14787.4 001291244.1_31929001_2 - 0.00054 19.5 0.3 0.0013 18.3 0.3 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.21 001291244.1_31929001_2 - 0.049 13.6 1.8 0.14 12.2 1.8 1.9 1 0 0 1 1 1 0 Zinc knuckle DUF5129 PF17173.2 001291244.1_31929001_2 - 0.23 10.4 1.3 0.36 9.8 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Mito_fiss_reg PF05308.9 001291244.1_31929001_2 - 2.2 8.2 5.5 4.7 7.1 5.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Orn_Arg_deC_N PF02784.14 001291634.1_31929001_2 - 4.5e-64 216.1 0.1 5.6e-64 215.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291634.1_31929001_2 - 6.8e-24 84.0 0.0 1.2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301793.1_31929001_1 - 4.7e-64 216.1 0.1 5.9e-64 215.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301793.1_31929001_1 - 7.1e-24 83.9 0.0 1.3e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Oest_recep PF02159.13 001282251.1_31924001_1 - 2.4e-57 193.1 7.3 4.8e-57 192.2 5.9 2.0 2 0 0 2 2 2 1 Oestrogen receptor Hormone_recep PF00104.28 001282251.1_31924001_1 - 1e-34 119.8 2.7 1.6e-34 119.2 2.7 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001282251.1_31924001_1 - 1.7e-31 108.4 13.9 2.8e-31 107.7 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ESR1_C PF12743.5 001282251.1_31924001_1 - 1.5e-22 78.9 5.6 3.1e-22 77.9 5.6 1.6 1 0 0 1 1 1 1 Oestrogen-type nuclear receptor final C-terminal Jiv90 PF14901.4 001282251.1_31924001_1 - 0.39 10.8 4.7 1.3 9.1 4.2 2.0 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Orn_Arg_deC_N PF02784.14 001294179.1_31925001_1 - 3.2e-68 229.7 0.0 4.1e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001294179.1_31925001_1 - 1.8e-18 66.5 0.0 3.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001294179.1_31925001_1 - 0.00064 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Hormone_5 PF00184.15 001282253.1_31922001_1 - 6.9e-34 116.4 25.9 1.1e-33 115.8 25.9 1.3 1 0 0 1 1 1 1 Neurohypophysial hormones, C-terminal Domain Hormone_4 PF00220.15 001282253.1_31922001_1 - 0.00015 21.2 3.3 0.00051 19.6 3.3 2.0 1 0 0 1 1 1 1 Neurohypophysial hormones, N-terminal Domain Orn_Arg_deC_N PF02784.14 001301750.1_13429001_1 - 2.3e-61 207.2 0.1 2.9e-61 206.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301750.1_13429001_1 - 2.4e-24 85.4 0.0 4.1e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291553.1_13429001_3 - 2.5e-61 207.1 0.1 3.1e-61 206.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291553.1_13429001_3 - 2.5e-24 85.4 0.0 4.3e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Globin PF00042.20 001279263.1_13422001_3 - 1.6e-29 102.5 0.0 3.5e-29 101.5 0.0 1.5 2 0 0 2 2 2 1 Globin Globin PF00042.20 001287785.1_13421001_1 - 7.1e-23 81.1 0.6 9.3e-23 80.8 0.2 1.4 2 0 0 2 2 2 1 Globin Orn_Arg_deC_N PF02784.14 001293738.1_13425001_1 - 3.9e-68 229.4 0.0 4.9e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293738.1_13425001_1 - 9.2e-20 70.7 0.0 1.7e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293738.1_13425001_1 - 2.9e-05 23.5 0.0 6.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Asp_protease_2 PF13650.4 001291188.1_13429001_1 - 0.00048 20.6 0.0 0.00078 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291188.1_13429001_1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291188.1_13429001_1 - 0.05 14.0 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291188.1_13429001_2 - 2.8e-15 56.2 3.8 4.8e-15 55.5 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291188.1_13429001_2 - 6.9e-15 54.8 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291188.1_13429001_2 - 0.00065 19.5 4.5 0.0014 18.4 4.5 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291188.1_13429001_2 - 0.0018 17.8 0.2 0.005 16.4 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291188.1_13429001_2 - 0.0053 16.7 4.3 0.0099 15.8 4.3 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF737 PF05300.9 001291188.1_13429001_2 - 0.025 14.8 1.8 0.045 14.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CENP-H PF05837.10 001291188.1_13429001_2 - 0.081 13.2 3.7 0.19 12.0 3.7 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-CCHC PF00098.21 001291188.1_13429001_2 - 0.086 12.8 2.2 0.36 10.9 2.2 2.2 1 0 0 1 1 1 0 Zinc knuckle bZIP_1 PF00170.19 001291188.1_13429001_2 - 0.1 12.6 4.4 0.26 11.3 4.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 001291188.1_13429001_2 - 0.17 11.5 4.8 0.32 10.6 4.8 1.3 1 0 0 1 1 1 0 IncA protein TolA_bind_tri PF16331.3 001291188.1_13429001_2 - 0.37 10.8 4.3 0.71 9.9 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation ZapB PF06005.10 001291188.1_13429001_2 - 0.41 11.0 9.3 0.96 9.8 9.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB SHE3 PF17078.3 001291188.1_13429001_2 - 0.45 10.1 6.4 0.93 9.0 6.4 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001291188.1_13429001_2 - 0.54 9.9 4.1 1.4 8.6 4.1 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.11 001291188.1_13429001_2 - 0.61 10.6 4.1 1.4 9.5 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001291188.1_13429001_2 - 0.62 8.8 5.9 1.1 8.0 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.6 001291188.1_13429001_2 - 1.1 9.1 7.3 2.5 8.0 7.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.3 001291188.1_13429001_2 - 1.9 8.5 6.9 4.3 7.3 6.9 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Globin PF00042.20 001281855.1_13422001_1 - 1.2e-28 99.7 0.1 1.7e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Globin ESP PF16590.3 001281855.1_13422001_1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Exocrine gland-secreting peptide LRR_9 PF14580.4 001282079.1_13422001_3 - 1.2e-12 47.6 0.0 5.1e-12 45.5 0.0 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.4 001282079.1_13422001_3 - 9.7e-07 28.3 3.0 9.7e-07 28.3 3.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.5 001282079.1_13422001_3 - 1.5e-06 28.2 9.3 0.00078 19.6 0.6 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001282079.1_13422001_3 - 4.2 8.1 10.5 79 4.2 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat Transferrin PF00405.15 001311351.1_06425001_1 - 2.4e-250 828.8 13.5 1.1e-166 553.8 0.3 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.5 001311351.1_06425001_1 - 1.8e-11 44.0 0.0 0.00011 21.7 0.0 2.6 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.18 001311351.1_06425001_1 - 0.089 12.1 0.0 2.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 P53 PF00870.16 001287369.1_52123001_3 - 4.7e-114 378.7 0.8 6.6e-114 378.2 0.8 1.2 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.9 001287369.1_52123001_3 - 4e-19 67.5 2.5 7.8e-19 66.6 2.5 1.5 1 0 0 1 1 1 1 P53 tetramerisation motif P53_TAD PF08563.9 001287369.1_52123001_3 - 3.3e-12 45.4 5.3 6.8e-12 44.4 5.3 1.6 1 0 0 1 1 1 1 P53 transactivation motif DEC-1_N PF04625.11 001287369.1_52123001_3 - 0.49 9.2 5.3 0.63 8.9 5.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Mito_fiss_reg PF05308.9 001293760.1_33625001_1 - 3.5 7.5 4.2 5.4 6.9 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Orn_Arg_deC_N PF02784.14 001293760.1_33625001_2 - 1.5e-67 227.5 0.0 1.9e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293760.1_33625001_2 - 1.6e-20 73.1 0.0 2.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293760.1_33625001_2 - 0.0075 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001291714.1_33626001_3 - 4e-65 219.6 0.1 5e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291714.1_33626001_3 - 7.3e-23 80.7 0.0 1.5e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301794.1_33626001_3 - 4e-65 219.6 0.1 5e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301794.1_33626001_3 - 3.9e-23 81.5 0.0 8.1e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF5032 PF16435.3 001301794.1_33626001_3 - 0.097 12.0 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) Orn_Arg_deC_N PF02784.14 001301797.1_52125001_2 - 5.9e-62 209.2 0.3 7.5e-62 208.8 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301797.1_52125001_2 - 2.6e-24 85.3 0.0 4.7e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Asp_protease_2 PF13650.4 001291331.1_52129001_1 - 0.00032 21.2 0.0 0.00058 20.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291331.1_52129001_1 - 0.0082 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291331.1_52129001_1 - 0.037 14.5 0.0 0.061 13.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291331.1_52129001_2 - 1.3e-15 57.3 1.8 1.4e-14 54.0 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291331.1_52129001_2 - 5.4e-15 55.1 0.0 9.6e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291331.1_52129001_2 - 0.0033 17.2 5.3 0.0055 16.4 5.3 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291331.1_52129001_2 - 0.0044 16.6 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291331.1_52129001_2 - 0.019 14.9 8.8 0.035 14.0 8.8 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.10 001291331.1_52129001_2 - 0.15 12.4 4.4 0.3 11.4 4.4 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CCDC106 PF15794.3 001291331.1_52129001_2 - 0.22 11.1 2.1 0.4 10.2 2.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 bZIP_1 PF00170.19 001291331.1_52129001_2 - 0.23 11.4 5.7 0.7 9.9 5.7 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.11 001291331.1_52129001_2 - 0.24 11.9 3.6 0.62 10.6 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1664 PF07889.10 001291331.1_52129001_2 - 0.25 11.2 1.0 0.53 10.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.12 001291331.1_52129001_2 - 0.3 10.7 5.2 0.64 9.6 5.2 1.5 1 0 0 1 1 1 0 IncA protein SlyX PF04102.10 001291331.1_52129001_2 - 0.33 11.5 2.9 0.9 10.1 2.9 1.7 1 0 0 1 1 1 0 SlyX ERM PF00769.17 001291331.1_52129001_2 - 0.38 10.4 6.1 0.63 9.7 6.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ZapB PF06005.10 001291331.1_52129001_2 - 0.39 11.1 10.0 0.9 9.9 10.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Spc7 PF08317.9 001291331.1_52129001_2 - 0.41 9.4 5.3 0.76 8.5 5.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.3 001291331.1_52129001_2 - 0.53 10.3 5.7 1 9.4 5.7 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.6 001291331.1_52129001_2 - 0.81 9.6 7.3 1.6 8.7 7.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SHE3 PF17078.3 001291331.1_52129001_2 - 1.9 8.0 7.1 3.4 7.2 7.1 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF3450 PF11932.6 001291331.1_52129001_2 - 2.3 7.3 4.3 3.9 6.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GIT_CC PF16559.3 001291331.1_52129001_2 - 3.2 7.7 8.2 8.7 6.3 8.2 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.13 001291331.1_52129001_2 - 3.3 7.4 7.8 9.9 5.9 7.8 1.8 1 1 0 1 1 1 0 Septum formation initiator Orn_Arg_deC_N PF02784.14 001291749.1_52124001_3 - 5e-62 209.4 0.3 6.3e-62 209.1 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291749.1_52124001_3 - 2.3e-24 85.5 0.0 4.1e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291750.1_52124001_3 - 1.9e-47 161.7 0.7 1.7e-26 93.1 0.2 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291750.1_52124001_3 - 2.3e-24 85.5 0.0 3.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain GATA PF00320.25 001290515.1_52123001_1 - 3.7e-29 99.9 19.6 1.5e-14 53.2 5.3 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.10 001290515.1_52123001_1 - 1.2e-05 24.6 8.0 0.019 14.3 0.7 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.8 001290515.1_52123001_1 - 0.011 15.7 5.1 2.2 8.4 0.6 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.8 001290515.1_52123001_1 - 0.013 15.4 2.4 2.4 8.2 0.1 2.8 2 1 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.10 001290515.1_52123001_1 - 0.073 13.1 5.2 1.1 9.3 0.4 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Prim_Zn_Ribbon PF08273.10 001290515.1_52123001_1 - 0.84 9.9 12.2 0.21 11.8 2.6 2.9 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.5 001290515.1_52123001_1 - 1.3 9.0 12.5 4.8 7.1 2.1 3.1 1 1 2 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.15 001290515.1_52123001_1 - 1.3 8.7 5.9 14 5.4 1.2 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Elf1 PF05129.11 001290515.1_52123001_1 - 6.1 6.8 8.3 11 6.0 0.3 2.8 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.9 001290515.1_52123001_1 - 7.5 6.4 13.4 6.8 6.6 2.7 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Vps36-NZF-N PF16988.3 001290515.1_52123001_1 - 9.3 5.6 8.7 1.3 8.4 0.4 2.9 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Orn_Arg_deC_N PF02784.14 001293785.1_08624001_1 - 3.5e-69 232.9 0.0 4.3e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293785.1_08624001_1 - 3.4e-18 65.6 0.0 6.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293785.1_08624001_1 - 4.3e-05 22.9 0.0 9e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Asp_protease_2 PF13650.4 001291335.1_08629001_1 - 0.00036 21.0 0.0 0.00058 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291335.1_08629001_1 - 0.017 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291335.1_08629001_1 - 0.058 13.8 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291335.1_08629001_2 - 1.2e-15 57.4 2.0 1.1e-14 54.3 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291335.1_08629001_2 - 6.7e-15 54.8 0.1 1.7e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291335.1_08629001_2 - 0.00031 20.5 2.2 0.00055 19.7 2.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001291335.1_08629001_2 - 0.0015 18.5 2.7 0.0027 17.7 2.7 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion zf-CCHC_5 PF14787.4 001291335.1_08629001_2 - 0.0019 17.8 0.2 0.0049 16.4 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CASP_C PF08172.10 001291335.1_08629001_2 - 0.0064 15.7 0.0 0.0097 15.1 0.0 1.2 1 0 0 1 1 1 1 CASP C terminal CENP-H PF05837.10 001291335.1_08629001_2 - 0.08 13.2 3.3 0.18 12.1 3.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-CCHC PF00098.21 001291335.1_08629001_2 - 0.1 12.6 2.2 0.35 10.9 2.2 2.1 1 0 0 1 1 1 0 Zinc knuckle SHE3 PF17078.3 001291335.1_08629001_2 - 0.11 12.1 4.5 0.23 11.0 4.5 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 IncA PF04156.12 001291335.1_08629001_2 - 0.14 11.8 4.1 0.28 10.8 4.1 1.4 1 0 0 1 1 1 0 IncA protein ZapB PF06005.10 001291335.1_08629001_2 - 0.21 12.0 8.6 0.58 10.5 8.6 1.7 1 0 0 1 1 1 0 Cell division protein ZapB TolA_bind_tri PF16331.3 001291335.1_08629001_2 - 0.24 11.4 3.9 0.53 10.3 3.9 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.6 001291335.1_08629001_2 - 0.28 11.1 5.5 0.7 9.8 5.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.9 001291335.1_08629001_2 - 0.36 9.5 4.8 0.6 8.8 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.6 001291335.1_08629001_2 - 0.36 9.9 2.5 0.61 9.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF972 PF06156.11 001291335.1_08629001_2 - 0.38 11.3 3.5 0.9 10.1 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.13 001291335.1_08629001_2 - 0.95 9.1 5.3 3 7.5 5.3 1.9 1 0 0 1 1 1 0 Septum formation initiator RCDG1 PF15725.3 001291335.1_08629001_2 - 0.99 9.7 10.5 2.5 8.5 10.5 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DUF3446 PF11928.6 001291335.1_08629001_2 - 1.4 9.2 12.1 4.4 7.6 12.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) GIT_CC PF16559.3 001291335.1_08629001_2 - 1.6 8.7 6.8 3.7 7.5 6.8 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291335.1_08629001_2 - 1.9 9.0 5.0 4.8 7.7 5.0 1.6 1 0 0 1 1 1 0 SlyX bZIP_1 PF00170.19 001291335.1_08629001_2 - 2 8.4 8.4 6.9 6.7 8.5 1.9 1 1 0 1 1 1 0 bZIP transcription factor Mito_fiss_reg PF05308.9 001291335.1_08629001_3 - 1.7 8.6 6.7 3.3 7.6 6.7 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Orn_Arg_deC_N PF02784.14 001291751.1_08628001_3 - 6.7e-64 215.6 0.1 8.5e-64 215.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291751.1_08628001_3 - 2.5e-24 85.3 0.0 4.4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AAA PF00004.27 001293056.1_33623001_1 - 5.8e-43 146.4 0.0 1.3e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293056.1_33623001_1 - 2.4e-07 30.9 0.0 5.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293056.1_33623001_1 - 3e-06 27.1 0.0 1.7e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293056.1_33623001_1 - 4.4e-06 27.0 0.2 8e-05 22.9 0.0 2.7 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293056.1_33623001_1 - 2.4e-05 24.5 1.3 0.0057 16.8 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293056.1_33623001_1 - 0.0001 21.5 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293056.1_33623001_1 - 0.0016 17.3 0.0 0.0034 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293056.1_33623001_1 - 0.0018 17.9 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293056.1_33623001_1 - 0.0019 18.3 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293056.1_33623001_1 - 0.0026 18.1 0.3 0.021 15.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.9 001293056.1_33623001_1 - 0.0068 16.1 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.19 001293056.1_33623001_1 - 0.0068 15.7 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.14 001293056.1_33623001_1 - 0.0077 15.6 0.1 0.14 11.4 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein ATPase PF06745.11 001293056.1_33623001_1 - 0.0088 15.3 0.0 0.025 13.8 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.4 001293056.1_33623001_1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293056.1_33623001_1 - 0.024 14.7 3.4 0.054 13.6 3.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293056.1_33623001_1 - 0.026 14.1 0.1 0.11 12.1 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293056.1_33623001_1 - 0.029 14.0 0.0 0.08 12.5 0.0 1.8 1 1 1 2 2 2 0 AAA domain TsaE PF02367.15 001293056.1_33623001_1 - 0.046 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293056.1_33623001_1 - 0.05 12.5 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.4 001293056.1_33623001_1 - 0.054 12.9 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.4 001293056.1_33623001_1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.11 001293056.1_33623001_1 - 0.057 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.4 001293056.1_33623001_1 - 0.067 12.8 0.4 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.20 001293056.1_33623001_1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.4 001293056.1_33623001_1 - 0.09 13.1 0.5 0.5 10.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.4 001293056.1_33623001_1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.10 001293056.1_33623001_1 - 0.23 11.3 3.5 1.3 8.9 0.9 2.7 3 0 0 3 3 3 0 Laminin Domain II Oest_recep PF02159.13 001279253.1_10724001_1 - 3.6e-51 173.1 6.5 1.1e-48 165.1 6.5 2.5 1 1 0 1 1 1 1 Oestrogen receptor Hormone_recep PF00104.28 001279253.1_10724001_1 - 1.3e-33 116.2 4.1 2.1e-33 115.6 4.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001279253.1_10724001_1 - 1.4e-31 108.6 13.9 2.3e-31 107.9 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ESR1_C PF12743.5 001279253.1_10724001_1 - 1.3e-24 85.5 1.9 2.4e-24 84.7 1.9 1.4 1 0 0 1 1 1 1 Oestrogen-type nuclear receptor final C-terminal Jiv90 PF14901.4 001279253.1_10724001_1 - 0.39 10.8 5.1 1.3 9.1 4.6 2.1 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Asp_protease_2 PF13650.4 001291113.1_10729001_1 - 0.00077 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291113.1_10729001_1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291113.1_10729001_1 - 0.051 14.0 0.0 0.087 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291113.1_10729001_2 - 3.1e-15 56.1 2.6 1.2e-14 54.2 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291113.1_10729001_2 - 4.9e-15 55.2 0.0 9e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001291113.1_10729001_2 - 0.00015 21.8 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291113.1_10729001_2 - 0.00021 21.1 2.3 0.00044 20.0 2.3 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291113.1_10729001_2 - 0.0019 17.7 0.2 0.005 16.4 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CASP_C PF08172.10 001291113.1_10729001_2 - 0.017 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 CASP C terminal SHE3 PF17078.3 001291113.1_10729001_2 - 0.042 13.4 3.1 0.086 12.4 3.1 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Spc29 PF17082.3 001291113.1_10729001_2 - 0.043 13.5 0.8 0.07 12.8 0.8 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Uso1_p115_C PF04871.11 001291113.1_10729001_2 - 0.062 13.5 2.2 0.11 12.8 2.2 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.6 001291113.1_10729001_2 - 0.086 12.0 1.2 0.14 11.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.10 001291113.1_10729001_2 - 0.11 12.8 7.6 0.26 11.6 7.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291113.1_10729001_2 - 0.2 12.2 2.3 0.49 10.9 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TolA_bind_tri PF16331.3 001291113.1_10729001_2 - 0.24 11.3 4.2 0.5 10.3 4.2 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation IncA PF04156.12 001291113.1_10729001_2 - 0.25 11.0 4.9 0.47 10.1 4.9 1.4 1 0 0 1 1 1 0 IncA protein zf-CCHC PF00098.21 001291113.1_10729001_2 - 0.3 11.1 5.0 0.36 10.9 2.2 2.6 2 0 0 2 2 2 0 Zinc knuckle Spc7 PF08317.9 001291113.1_10729001_2 - 0.32 9.7 3.7 0.56 8.9 3.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.6 001291113.1_10729001_2 - 0.78 9.6 6.8 1.6 8.6 6.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.13 001291113.1_10729001_2 - 1.1 8.9 5.2 2.8 7.6 5.2 1.7 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.10 001291113.1_10729001_2 - 1.4 9.4 4.9 3.6 8.1 4.9 1.6 1 0 0 1 1 1 0 SlyX RCDG1 PF15725.3 001291113.1_10729001_2 - 1.6 9.1 8.3 3.8 7.9 8.3 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein GIT_CC PF16559.3 001291113.1_10729001_2 - 3.4 7.6 7.3 8.6 6.3 7.3 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.19 001291113.1_10729001_2 - 3.5 7.7 8.3 14 5.7 8.3 2.0 1 1 1 2 2 2 0 bZIP transcription factor CENP-H PF05837.10 001291113.1_10729001_2 - 4.9 7.5 10.0 0.87 9.9 4.1 2.4 3 0 0 3 3 2 0 Centromere protein H (CENP-H) CAP_N PF01213.17 001291113.1_10729001_2 - 8.6 5.6 12.1 16 4.7 12.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RNase_H PF00075.22 001285786.1_10722001_1 - 5.7e-45 152.9 0.0 9.3e-45 152.2 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285786.1_10722001_1 - 1e-18 67.2 1.5 2.1e-18 66.2 1.5 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285786.1_10722001_1 - 0.00051 19.6 0.0 0.0019 17.8 0.0 2.0 3 0 0 3 3 3 1 Reverse transcriptase-like Orn_Arg_deC_N PF02784.14 001291517.1_10729001_2 - 1e-62 211.7 0.1 1.3e-62 211.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291517.1_10729001_2 - 3.4e-24 84.9 0.0 5.9e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301743.1_10729001_3 - 9.6e-63 211.8 0.1 1.2e-62 211.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301743.1_10729001_3 - 3.2e-24 85.0 0.0 5.7e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Cyt-b5 PF00173.26 001308580.1_39523001_3 - 3.7e-14 52.5 0.0 6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MHC_I PF00129.16 001308452.1_39523001_1 - 6.3e-91 302.7 0.4 8.9e-91 302.2 0.4 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001308452.1_39523001_1 - 1.9e-17 63.4 0.0 4e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001308452.1_39523001_1 - 1.1e-16 60.2 1.3 2.3e-16 59.3 1.3 1.6 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001308452.1_39523001_1 - 9.7e-06 26.0 0.3 0.00029 21.3 0.0 2.9 1 1 1 2 2 2 1 Immunoglobulin domain ig PF00047.23 001308452.1_39523001_1 - 0.00034 20.6 0.3 0.0014 18.7 0.0 2.1 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.4 001308452.1_39523001_1 - 0.0009 19.4 0.0 0.0075 16.5 0.0 2.5 3 0 0 3 3 3 1 Immunoglobulin domain MHC_I_3 PF16497.3 001308452.1_39523001_1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 MHC-I family domain C2-set_2 PF08205.10 001308452.1_39523001_1 - 0.0031 17.4 0.1 0.006 16.5 0.1 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain EphA2_TM PF14575.4 001308452.1_39523001_1 - 0.037 14.7 0.1 0.082 13.6 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4245 PF14030.4 001308452.1_39523001_1 - 0.23 11.3 2.1 9.6 6.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4245) P12 PF12669.5 001308452.1_39523001_1 - 0.69 10.2 2.3 1.3 9.3 2.3 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Orn_Arg_deC_N PF02784.14 001293796.1_42225001_2 - 1.3e-70 237.5 0.0 1.7e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293796.1_42225001_2 - 5.7e-18 64.9 0.0 1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293796.1_42225001_2 - 0.00028 20.2 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Globin PF00042.20 001301376.1_52421001_1 - 3.8e-22 78.8 0.5 5.8e-22 78.2 0.5 1.3 1 0 0 1 1 1 1 Globin 7tm_1 PF00001.19 001082693.1_37923001_1 - 1e-69 234.6 0.0 1.3e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001082693.1_37923001_1 - 1.9e-07 31.0 9.2 3.3e-06 26.9 2.8 2.3 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.7 001082693.1_37923001_1 - 1.5e-06 27.7 17.6 2.7e-06 26.8 3.3 2.5 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001082693.1_37923001_1 - 0.00016 21.0 6.4 0.00016 21.0 6.4 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4727 PF15856.3 001082693.1_37923001_1 - 0.065 12.7 0.3 0.76 9.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4727) Orn_Arg_deC_N PF02784.14 001291555.1_33429001_2 - 4.2e-64 216.2 0.1 5.3e-64 215.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291555.1_33429001_2 - 6.2e-24 84.1 0.0 1.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PMP22_Claudin PF00822.18 001287364.1_52122001_1 - 3.8e-52 176.4 11.1 4.4e-52 176.2 11.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001287364.1_52122001_1 - 3.7e-11 43.0 11.2 4.6e-10 39.4 11.2 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.10 001287364.1_52122001_1 - 0.00072 19.1 3.0 0.00072 19.1 3.0 1.9 1 1 1 2 2 2 1 SUR7/PalI family DUF3169 PF11368.6 001287364.1_52122001_1 - 0.0044 16.5 0.5 0.0044 16.5 0.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) DUF996 PF06195.11 001287364.1_52122001_1 - 0.013 15.6 5.3 0.018 15.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF4134 PF13572.4 001287364.1_52122001_1 - 0.016 15.4 3.5 0.016 15.4 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Amastin PF07344.9 001287364.1_52122001_1 - 0.086 12.6 9.1 0.048 13.4 6.7 1.8 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF898 PF05987.11 001287364.1_52122001_1 - 0.092 11.6 8.6 0.01 14.8 2.5 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) YccF PF03733.11 001287364.1_52122001_1 - 0.23 12.1 0.5 0.23 12.1 0.5 4.3 5 0 0 5 5 5 0 Inner membrane component domain DUF2613 PF11021.6 001287364.1_52122001_1 - 0.3 11.1 0.0 0.3 11.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) DUF962 PF06127.9 001287364.1_52122001_1 - 0.88 9.6 3.0 1.5 8.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF962) FtsX PF02687.19 001287364.1_52122001_1 - 1.2 9.0 14.8 0.49 10.3 0.7 2.4 2 1 0 2 2 2 0 FtsX-like permease family DUF4131 PF13567.4 001287364.1_52122001_1 - 2.5 7.5 8.2 0.4 10.1 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF2207 PF09972.7 001287364.1_52122001_1 - 3 6.4 9.3 0.21 10.2 4.0 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.4 001287364.1_52122001_1 - 4.7 7.5 15.7 4.5 7.6 11.7 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF4064) Orn_Arg_deC_N PF02784.14 001301810.1_42228001_1 - 6e-64 215.7 0.1 7.6e-64 215.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301810.1_42228001_1 - 3.5e-24 84.9 0.0 6.6e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Cyclin_N PF00134.21 001287376.1_52125001_1 - 3.4e-23 81.7 1.3 3e-20 72.2 0.2 2.7 2 0 0 2 2 2 2 Cyclin, N-terminal domain Tetraspannin PF00335.18 001287371.1_52122001_1 - 2.8e-46 157.8 13.9 3.3e-46 157.6 13.9 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF21 PF01595.18 001287371.1_52122001_1 - 2.6 7.6 7.2 1.3 8.5 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF21 XPA_N PF01286.16 001287371.1_52122001_3 - 0.14 12.1 0.2 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 XPA protein N-terminal Ig_2 PF13895.4 001302660.1_11723001_1 - 1.7e-07 31.3 0.6 0.0067 16.6 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001302660.1_11723001_1 - 1.7e-07 31.6 0.2 0.0017 18.8 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001302660.1_11723001_1 - 1.2e-06 28.5 0.0 3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 001302660.1_11723001_1 - 1.5e-05 24.9 0.3 0.3 11.2 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001302660.1_11723001_1 - 0.00085 19.2 0.0 0.072 13.0 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain LAX PF15681.3 001302660.1_11723001_1 - 0.14 10.6 0.6 0.24 9.9 0.6 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X Vpu PF00558.17 001302660.1_11723001_1 - 0.19 11.4 1.0 0.44 10.2 1.0 1.5 1 0 0 1 1 1 0 Vpu protein Ald_Xan_dh_C2 PF02738.16 001303261.1_29229001_1 - 1.4e-184 614.5 0.0 1.7e-184 614.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001303261.1_29229001_1 - 2.8e-44 150.7 0.0 5.9e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001303261.1_29229001_1 - 6.8e-34 116.4 0.1 1.5e-33 115.3 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001303261.1_29229001_1 - 1.4e-31 108.1 0.7 3.7e-31 106.8 0.7 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001303261.1_29229001_1 - 7.4e-30 103.0 0.0 2.7e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001303261.1_29229001_1 - 9.6e-09 34.9 2.6 5e-08 32.7 0.0 2.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain RhoGAP PF00620.25 001303261.1_29229001_1 - 0.035 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain ACP_syn_III_C PF08541.8 001303261.1_29229001_1 - 0.11 12.5 0.0 0.71 10.0 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal IL10 PF00726.15 001303549.1_08522001_2 - 2e-10 40.3 0.8 2.8e-10 39.8 0.8 1.2 1 0 0 1 1 1 1 Interleukin 10 IL22 PF14565.4 001303549.1_08522001_2 - 1.2e-06 28.7 0.3 2e-06 28.0 0.3 1.3 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor E1_DerP2_DerF2 PF02221.13 001305897.1_29721001_1 - 1.6e-15 57.6 0.2 1.9e-15 57.4 0.2 1.1 1 0 0 1 1 1 1 ML domain MHC_I PF00129.16 001305902.1_29723001_1 - 1.3e-92 308.1 0.8 1.9e-92 307.6 0.8 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001305902.1_29723001_1 - 3.2e-17 62.6 0.0 7.1e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001305902.1_29723001_1 - 2.5e-13 49.6 10.9 5.4e-13 48.5 10.9 1.6 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001305902.1_29723001_1 - 2.5e-06 27.9 0.8 0.018 15.5 0.0 3.1 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 001305902.1_29723001_1 - 0.00012 21.9 1.1 0.0005 20.0 0.1 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001305902.1_29723001_1 - 0.0017 18.3 0.1 0.0061 16.6 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Tetraspannin PF00335.18 001305901.1_29722001_1 - 6e-47 160.0 13.8 6.9e-47 159.8 13.8 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF21 PF01595.18 001305901.1_29722001_1 - 8.4 5.9 7.6 4 7.0 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF21 V-set_2 PF15910.3 001305918.1_29722001_2 - 1.5e-13 50.7 1.0 2.1e-13 50.2 1.0 1.2 1 0 0 1 1 1 1 ICOS V-set domain V-set PF07686.15 001305918.1_29722001_2 - 5.3e-06 26.4 0.6 7.6e-06 25.9 0.3 1.4 2 0 0 2 2 2 1 Immunoglobulin V-set domain Syndecan PF01034.18 001305918.1_29722001_2 - 0.13 12.1 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain MHC_II_alpha PF00993.18 001305927.1_29722001_1 - 2.1e-35 120.1 0.1 3e-35 119.6 0.1 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001305927.1_29722001_1 - 1.4e-29 101.1 0.1 2.7e-29 100.2 0.1 1.5 1 0 0 1 1 1 1 C1-set C-terminal domain C1-set PF07654.13 001305927.1_29722001_1 - 7.7e-23 80.7 0.0 1.2e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001305927.1_29722001_1 - 3e-05 24.4 0.0 6.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.13 001305927.1_29722001_1 - 0.00064 19.5 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 Marek's disease glycoprotein A C2-set_2 PF08205.10 001305927.1_29722001_1 - 0.027 14.4 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 001305927.1_29722001_1 - 0.045 14.0 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain PA14 PF07691.10 001305927.1_29722001_1 - 0.051 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 PA14 domain BST2 PF16716.3 001305931.1_29722001_1 - 3.1e-35 120.5 6.8 5.1e-35 119.8 6.8 1.3 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 MAD PF05557.11 001305931.1_29722001_1 - 0.00019 19.8 4.3 0.00023 19.6 4.3 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein CALCOCO1 PF07888.9 001305931.1_29722001_1 - 0.0016 17.0 2.5 0.002 16.7 2.5 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.7 001305931.1_29722001_1 - 0.0025 17.7 3.5 0.0027 17.6 2.3 1.6 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.10 001305931.1_29722001_1 - 0.0041 17.6 3.8 0.0064 16.9 0.2 2.2 1 1 1 2 2 2 1 SlyX ATG16 PF08614.9 001305931.1_29722001_1 - 0.0042 17.2 7.4 0.0084 16.2 7.4 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Bap31 PF05529.10 001305931.1_29722001_1 - 0.0057 16.2 2.4 0.0057 16.2 2.4 1.5 2 0 0 2 2 1 1 B-cell receptor-associated protein 31-like NRBF2 PF08961.8 001305931.1_29722001_1 - 0.009 15.5 0.5 0.012 15.1 0.5 1.2 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Filament PF00038.19 001305931.1_29722001_1 - 0.012 15.1 4.5 0.018 14.5 4.4 1.3 1 1 0 1 1 1 0 Intermediate filament protein DUF2353 PF09789.7 001305931.1_29722001_1 - 0.013 14.9 1.0 0.016 14.5 1.0 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CASP_C PF08172.10 001305931.1_29722001_1 - 0.017 14.3 0.7 0.022 14.0 0.7 1.3 1 0 0 1 1 1 0 CASP C terminal Lebercilin PF15619.4 001305931.1_29722001_1 - 0.02 14.4 2.9 0.03 13.8 2.9 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.6 001305931.1_29722001_1 - 0.024 14.5 0.8 0.024 14.5 0.8 1.5 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.6 001305931.1_29722001_1 - 0.03 14.4 3.7 0.07 13.2 3.5 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.5 001305931.1_29722001_1 - 0.031 14.3 2.4 0.031 14.3 2.4 1.7 1 1 1 2 2 2 0 Tropomyosin like Spc7 PF08317.9 001305931.1_29722001_1 - 0.038 12.7 4.4 0.047 12.4 4.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein EMP24_GP25L PF01105.22 001305931.1_29722001_1 - 0.039 13.8 0.7 0.039 13.8 0.7 1.9 2 0 0 2 2 1 0 emp24/gp25L/p24 family/GOLD IncA PF04156.12 001305931.1_29722001_1 - 0.039 13.6 14.3 0.037 13.7 12.5 2.0 1 1 0 1 1 1 0 IncA protein Tropomyosin PF00261.18 001305931.1_29722001_1 - 0.04 13.1 5.9 0.037 13.3 1.5 1.7 1 1 1 2 2 2 0 Tropomyosin GAS PF13851.4 001305931.1_29722001_1 - 0.042 13.1 3.0 0.037 13.3 1.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lipoprotein_7 PF01540.14 001305931.1_29722001_1 - 0.043 13.0 0.6 0.053 12.7 0.6 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein APG6 PF04111.10 001305931.1_29722001_1 - 0.048 12.9 3.0 0.062 12.6 3.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Jnk-SapK_ap_N PF09744.7 001305931.1_29722001_1 - 0.06 13.4 3.3 0.085 12.9 3.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.4 001305931.1_29722001_1 - 0.062 12.7 2.5 0.071 12.5 2.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc24 PF08286.9 001305931.1_29722001_1 - 0.062 13.4 4.6 0.053 13.6 2.0 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.9 001305931.1_29722001_1 - 0.066 13.5 1.0 0.17 12.2 0.5 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FliJ PF02050.14 001305931.1_29722001_1 - 0.067 13.3 3.6 0.16 12.0 3.6 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.10 001305931.1_29722001_1 - 0.079 12.9 5.1 0.29 11.1 4.5 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.3 001305931.1_29722001_1 - 0.086 13.6 3.4 0.13 13.1 3.4 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF972 PF06156.11 001305931.1_29722001_1 - 0.087 13.3 1.1 0.14 12.7 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) SYCE1 PF15233.4 001305931.1_29722001_1 - 0.096 12.6 2.8 0.19 11.7 2.8 1.4 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 GrpE PF01025.17 001305931.1_29722001_1 - 0.1 12.1 2.4 0.1 12.1 1.3 1.5 1 1 0 1 1 1 0 GrpE CENP-H PF05837.10 001305931.1_29722001_1 - 0.11 12.8 6.2 0.32 11.3 5.2 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF3450 PF11932.6 001305931.1_29722001_1 - 0.11 11.7 4.2 0.15 11.2 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4200 PF13863.4 001305931.1_29722001_1 - 0.11 12.7 2.7 0.17 12.1 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Macoilin PF09726.7 001305931.1_29722001_1 - 0.11 10.9 1.9 0.13 10.7 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein CCDC-167 PF15188.4 001305931.1_29722001_1 - 0.11 12.7 1.9 0.23 11.7 1.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Golgin_A5 PF09787.7 001305931.1_29722001_1 - 0.14 11.5 4.0 0.17 11.2 4.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 T2SSM PF04612.10 001305931.1_29722001_1 - 0.14 12.1 2.7 0.31 11.0 0.2 2.0 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M DUF2205 PF10224.7 001305931.1_29722001_1 - 0.32 10.9 3.2 0.33 10.8 1.4 1.9 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) V_ATPase_I PF01496.17 001305931.1_29722001_1 - 0.32 8.7 0.8 0.37 8.5 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.10 001305931.1_29722001_1 - 0.35 11.2 6.3 0.22 11.8 1.9 2.3 1 1 1 2 2 2 0 Cell division protein ZapB KELK PF15796.3 001305931.1_29722001_1 - 0.38 11.1 3.6 0.35 11.3 1.6 1.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ABC_tran_CTD PF16326.3 001305931.1_29722001_1 - 0.43 10.7 4.8 6.4 7.0 4.5 2.7 1 1 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.13 001305931.1_29722001_1 - 2.5 7.8 7.5 1.1 8.9 0.4 2.8 1 1 2 3 3 3 0 Septum formation initiator IL13 PF03487.11 001305946.1_10821001_1 - 2.5e-69 231.0 0.1 2.9e-69 230.8 0.1 1.0 1 0 0 1 1 1 1 Interleukin-13 TNF PF00229.16 001305957.1_10822001_1 - 1.2e-38 131.8 0.0 1.7e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family BST2 PF16716.3 001305963.1_10822001_1 - 3e-35 120.5 6.5 4.9e-35 119.8 6.5 1.3 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 MAD PF05557.11 001305963.1_10822001_1 - 0.0002 19.7 3.8 0.00023 19.5 3.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein CALCOCO1 PF07888.9 001305963.1_10822001_1 - 0.0017 16.9 2.3 0.0021 16.6 2.3 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.7 001305963.1_10822001_1 - 0.0021 18.0 3.2 0.0023 17.8 2.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bap31 PF05529.10 001305963.1_10822001_1 - 0.004 16.7 2.1 0.0071 15.9 2.1 1.3 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like SlyX PF04102.10 001305963.1_10822001_1 - 0.0043 17.5 3.6 0.0064 16.9 0.2 2.2 1 1 1 2 2 2 1 SlyX ATG16 PF08614.9 001305963.1_10822001_1 - 0.0045 17.1 7.2 0.0093 16.0 7.2 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.6 001305963.1_10822001_1 - 0.0063 16.6 3.3 0.015 15.4 3.1 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding NRBF2 PF08961.8 001305963.1_10822001_1 - 0.0092 15.5 0.5 0.012 15.0 0.5 1.2 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Spc24 PF08286.9 001305963.1_10822001_1 - 0.011 15.8 1.9 0.018 15.1 0.6 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Filament PF00038.19 001305963.1_10822001_1 - 0.013 15.0 4.3 0.021 14.3 4.2 1.3 1 1 0 1 1 1 0 Intermediate filament protein DUF2353 PF09789.7 001305963.1_10822001_1 - 0.014 14.7 0.8 0.018 14.3 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CASP_C PF08172.10 001305963.1_10822001_1 - 0.018 14.2 0.7 0.022 14.0 0.7 1.2 1 0 0 1 1 1 0 CASP C terminal Lebercilin PF15619.4 001305963.1_10822001_1 - 0.023 14.2 2.5 0.034 13.7 2.5 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.6 001305963.1_10822001_1 - 0.024 14.5 0.8 0.024 14.5 0.8 1.5 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding EMP24_GP25L PF01105.22 001305963.1_10822001_1 - 0.031 14.1 0.4 0.031 14.1 0.4 1.4 2 0 0 2 2 1 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.9 001305963.1_10822001_1 - 0.037 12.8 4.3 0.045 12.5 4.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin PF00261.18 001305963.1_10822001_1 - 0.039 13.2 5.5 0.039 13.2 1.3 1.7 1 1 1 2 2 2 0 Tropomyosin Lipoprotein_7 PF01540.14 001305963.1_10822001_1 - 0.039 13.1 0.7 0.048 12.8 0.7 1.0 1 0 0 1 1 1 0 Adhesin lipoprotein CENP-H PF05837.10 001305963.1_10822001_1 - 0.041 14.2 5.6 0.099 12.9 4.8 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GAS PF13851.4 001305963.1_10822001_1 - 0.044 13.0 2.8 0.043 13.1 1.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.5 001305963.1_10822001_1 - 0.049 13.6 4.6 0.038 14.0 2.6 1.7 1 1 1 2 2 2 0 Tropomyosin like APG6 PF04111.10 001305963.1_10822001_1 - 0.05 12.9 2.6 0.063 12.5 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FliJ PF02050.14 001305963.1_10822001_1 - 0.061 13.4 3.4 0.16 12.1 3.4 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein FlaC_arch PF05377.9 001305963.1_10822001_1 - 0.065 13.5 0.9 0.17 12.2 0.5 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.3 001305963.1_10822001_1 - 0.077 13.8 3.0 0.11 13.3 3.0 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain HAUS-augmin3 PF14932.4 001305963.1_10822001_1 - 0.08 12.3 2.3 0.09 12.1 2.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF972 PF06156.11 001305963.1_10822001_1 - 0.085 13.4 1.0 0.14 12.7 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.10 001305963.1_10822001_1 - 0.085 12.8 5.2 0.33 10.9 4.4 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GrpE PF01025.17 001305963.1_10822001_1 - 0.1 12.1 2.4 0.072 12.6 0.9 1.5 2 0 0 2 2 2 0 GrpE DUF4200 PF13863.4 001305963.1_10822001_1 - 0.11 12.8 2.3 0.16 12.2 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Macoilin PF09726.7 001305963.1_10822001_1 - 0.11 10.9 1.8 0.13 10.7 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3450 PF11932.6 001305963.1_10822001_1 - 0.12 11.5 4.0 0.16 11.1 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Golgin_A5 PF09787.7 001305963.1_10822001_1 - 0.12 11.6 3.7 0.15 11.4 3.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 CCDC-167 PF15188.4 001305963.1_10822001_1 - 0.14 12.4 1.7 0.25 11.6 1.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2205 PF10224.7 001305963.1_10822001_1 - 0.27 11.1 2.5 0.34 10.8 1.3 1.7 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) KELK PF15796.3 001305963.1_10822001_1 - 0.31 11.4 3.2 0.3 11.5 1.3 1.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ZapB PF06005.10 001305963.1_10822001_1 - 0.35 11.2 6.2 0.2 12.0 1.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB ABC_tran_CTD PF16326.3 001305963.1_10822001_1 - 0.57 10.3 4.6 6.2 7.0 4.3 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.13 001305963.1_10822001_1 - 0.91 9.2 5.8 1.2 8.9 0.4 2.7 1 1 2 3 3 3 0 Septum formation initiator IncA PF04156.12 001305963.1_10822001_1 - 7.6 6.1 17.1 7.8 6.1 14.4 2.2 1 1 0 1 1 1 0 IncA protein zf-RING_UBOX PF13445.4 001305964.1_10823001_1 - 5.7e-13 48.5 6.1 6.4e-13 48.4 3.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001305964.1_10823001_1 - 9.7e-11 41.5 8.8 9.7e-11 41.5 8.8 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING SPRY PF00622.26 001305964.1_10823001_1 - 1e-10 41.6 0.3 2.2e-10 40.6 0.3 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4 PF00097.23 001305964.1_10823001_1 - 8.2e-10 38.3 8.2 2.1e-09 36.9 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001305964.1_10823001_1 - 2.3e-08 33.6 8.7 9.9e-08 31.6 8.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001305964.1_10823001_1 - 6.7e-08 32.5 8.0 6.7e-08 32.5 8.0 2.0 2 0 0 2 2 1 1 Ring finger domain zf-B_box PF00643.22 001305964.1_10823001_1 - 8.2e-08 32.1 4.3 8.2e-08 32.1 4.3 3.0 3 1 0 3 3 2 1 B-box zinc finger zf-C3HC4_3 PF13920.4 001305964.1_10823001_1 - 1.3e-07 31.2 6.1 1.3e-07 31.2 6.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001305964.1_10823001_1 - 2e-07 30.7 6.2 2e-07 30.7 6.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.13 001305964.1_10823001_1 - 2.9e-05 24.0 0.0 6.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain TMF_TATA_bd PF12325.6 001305964.1_10823001_1 - 0.00069 19.7 2.0 0.00069 19.7 2.0 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding zf-RING_10 PF16685.3 001305964.1_10823001_1 - 0.021 14.8 4.3 0.021 14.8 4.3 2.0 2 0 0 2 2 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.4 001305964.1_10823001_1 - 0.021 14.6 9.5 0.021 14.6 9.5 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-Nse PF11789.6 001305964.1_10823001_1 - 0.025 14.3 4.8 0.066 12.9 4.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.9 001305964.1_10823001_1 - 0.072 12.9 4.9 0.051 13.4 1.4 2.4 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.4 001305964.1_10823001_1 - 0.079 12.7 4.7 0.12 12.2 3.4 2.0 2 1 0 2 2 1 0 zf-RING of BARD1-type protein AAA_11 PF13086.4 001305964.1_10823001_1 - 0.29 10.7 5.7 0.43 10.1 5.7 1.2 1 0 0 1 1 1 0 AAA domain zf-RING_11 PF17123.3 001305964.1_10823001_1 - 0.4 10.3 4.8 1.6 8.4 4.8 2.2 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.4 001305964.1_10823001_1 - 0.45 10.5 4.0 0.52 10.3 1.1 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.4 001305964.1_10823001_1 - 0.65 9.6 8.3 5.7 6.6 8.6 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.5 001305964.1_10823001_1 - 1.3 9.2 10.8 0.53 10.5 6.7 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain LsmAD PF06741.11 001305964.1_10823001_1 - 2.4 8.7 5.1 6 7.4 4.6 1.9 1 1 0 1 1 1 0 LsmAD domain DUF4407 PF14362.4 001305964.1_10823001_1 - 5.3 6.2 7.0 7.6 5.6 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-UBR PF02207.18 001305964.1_10823001_1 - 6 7.0 11.8 0.42 10.7 1.4 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-RING_UBOX PF13445.4 001305965.1_10823001_1 - 1.3e-12 47.3 6.0 3.6e-11 42.8 2.4 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001305965.1_10823001_1 - 1.2e-11 44.4 8.2 1.2e-11 44.4 8.2 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.23 001305965.1_10823001_1 - 5.8e-10 38.8 7.2 1.5e-09 37.4 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.22 001305965.1_10823001_1 - 9.3e-09 35.2 3.9 9.3e-09 35.2 3.9 3.1 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4_2 PF13923.4 001305965.1_10823001_1 - 1.6e-08 34.1 7.2 2.9e-07 30.1 8.2 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SPRY PF00622.26 001305965.1_10823001_1 - 1.1e-07 31.8 1.8 1.6e-07 31.3 0.2 1.9 2 0 0 2 2 2 1 SPRY domain zf-RING_2 PF13639.4 001305965.1_10823001_1 - 2.4e-07 30.8 7.0 2.4e-07 30.8 7.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.4 001305965.1_10823001_1 - 2.2e-06 27.4 5.4 2.2e-06 27.4 5.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001305965.1_10823001_1 - 4.7e-06 26.2 5.2 4.7e-06 26.2 5.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.6 001305965.1_10823001_1 - 0.002 17.8 4.4 0.0066 16.1 4.4 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.13 001305965.1_10823001_1 - 0.0026 17.7 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.4 001305965.1_10823001_1 - 0.0073 16.0 5.2 0.025 14.3 5.2 1.9 1 1 0 1 1 1 1 zf-RING of BARD1-type protein SF-assemblin PF06705.9 001305965.1_10823001_1 - 0.0074 15.5 11.0 1.7 7.8 9.1 2.3 1 1 1 2 2 2 2 SF-assemblin/beta giardin zf-RING_10 PF16685.3 001305965.1_10823001_1 - 0.0093 16.0 4.5 0.0093 16.0 4.5 2.6 1 1 1 2 2 2 1 zinc RING finger of MSL2 ABC1 PF03109.14 001305965.1_10823001_1 - 0.094 12.8 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 ABC1 family UBZ_FAAP20 PF15750.3 001305965.1_10823001_1 - 0.095 12.5 2.6 0.91 9.4 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Prok-RING_4 PF14447.4 001305965.1_10823001_1 - 0.12 12.1 15.8 0.036 13.8 10.3 2.7 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.4 001305965.1_10823001_1 - 0.22 11.2 5.4 1.6 8.4 5.7 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.12 001305965.1_10823001_1 - 0.39 10.4 0.1 0.39 10.4 0.1 3.7 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-RING_11 PF17123.3 001305965.1_10823001_1 - 1.4 8.5 5.7 10 5.8 3.8 2.9 2 1 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.5 001305965.1_10823001_1 - 2 8.7 14.8 0.065 13.4 5.2 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-Di19 PF05605.10 001305965.1_10823001_1 - 4.7 7.5 11.5 8.5 6.6 0.1 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding RRM_3 PF08777.9 001305965.1_10823001_1 - 6.7 6.7 8.0 2.7 8.0 4.5 2.0 1 1 1 2 2 2 0 RNA binding motif IRF-3 PF10401.7 001305977.1_10824001_2 - 3.2e-47 160.5 0.0 4.6e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.15 001305977.1_10824001_2 - 7.3e-38 128.9 0.0 1.6e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor C2-set PF05790.13 001308337.1_10823001_1 - 1.2e-15 57.3 2.3 2.4e-15 56.3 2.3 1.5 1 0 0 1 1 1 1 Immunoglobulin C2-set domain V-set PF07686.15 001308337.1_10823001_1 - 2.7e-08 33.8 0.0 6.7e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.4 001308337.1_10823001_1 - 0.00049 20.3 2.0 0.00071 19.7 0.8 1.9 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.14 001308337.1_10823001_1 - 0.0068 16.3 3.7 0.12 12.3 0.4 3.2 1 1 1 2 2 2 1 Immunoglobulin I-set domain EphA2_TM PF14575.4 001308337.1_10823001_1 - 0.069 13.8 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Receptor_2B4 PF11465.6 001308337.1_10823001_1 - 0.097 12.8 0.4 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 DUF1191 PF06697.10 001308337.1_10823001_1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SNURF PF07192.9 001308337.1_10823001_3 - 0.054 13.2 0.3 0.099 12.3 0.3 1.3 1 0 0 1 1 1 0 SNURF/RPN4 protein IL2 PF00715.15 001308990.1_47121001_1 - 1.9e-22 79.6 0.1 2.5e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Interleukin 2 IL15 PF02372.13 001308990.1_47121001_1 - 7e-07 29.2 0.0 9.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Interleukin 15 Glyco_transf_6 PF03414.11 132146.1_29724120_2 - 1.2e-100 336.3 1.5 1.6e-100 335.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 7tm_1 PF00001.19 001318077.1_39523001_1 - 4.6e-49 166.9 7.3 6.1e-49 166.5 7.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001318077.1_39523001_1 - 3.2e-07 29.9 1.7 5e-07 29.2 1.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001318077.1_39523001_1 - 7.3e-07 29.1 1.5 1.1e-06 28.5 1.5 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001318077.1_39523001_1 - 0.041 13.1 3.1 0.068 12.3 3.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Caldesmon PF02029.13 001169066.1_40422001_1 - 4.5e-26 91.6 19.0 5.4e-26 91.3 5.6 2.5 2 1 0 2 2 2 2 Caldesmon DASH_Dad1 PF08649.8 001169066.1_40422001_1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad1 DUF3528 PF12045.6 001168900.1_40422001_1 - 3.3e-64 215.7 0.2 4.8e-64 215.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeobox PF00046.27 001168900.1_40422001_1 - 4.3e-20 71.1 7.4 6.7e-20 70.5 7.4 1.3 1 0 0 1 1 1 1 Homeobox domain DTHCT PF08070.9 001168900.1_40422001_1 - 0.019 15.6 1.5 0.035 14.7 1.5 1.4 1 0 0 1 1 1 0 DTHCT (NUC029) region Homeobox_KN PF05920.9 001168900.1_40422001_1 - 0.046 13.5 0.8 0.096 12.5 0.8 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF1178 PF06676.9 001168900.1_40422001_2 - 0.33 11.2 0.2 0.33 11.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Oest_recep PF02159.13 001164587.1_40424001_1 - 5.8e-65 217.8 6.0 6.7e-65 217.6 4.3 1.9 2 0 0 2 2 2 1 Oestrogen receptor Hormone_recep PF00104.28 001164587.1_40424001_1 - 7.5e-35 120.3 3.3 1.2e-34 119.6 3.3 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001164587.1_40424001_1 - 1.5e-31 108.5 13.9 2.4e-31 107.9 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ESR1_C PF12743.5 001164587.1_40424001_1 - 3.3e-25 87.4 1.3 6.2e-25 86.6 1.3 1.5 1 0 0 1 1 1 1 Oestrogen-type nuclear receptor final C-terminal Jiv90 PF14901.4 001164587.1_40424001_1 - 0.29 11.2 4.9 1.2 9.2 4.5 2.2 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone NDK PF00334.17 001204749.1_37921001_1 - 7.3e-55 184.5 0.0 8.3e-55 184.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Benyvirus_14KDa PF07255.9 001204749.1_37921001_1 - 0.029 14.4 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Benyvirus 14KDa protein Radical_SAM PF04055.19 001279531.1_40423001_1 - 7.5e-16 58.8 0.1 3.4e-15 56.7 0.1 2.1 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.4 001279531.1_40423001_1 - 1.8e-08 34.4 0.5 9.8e-07 28.8 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.4 001279531.1_40423001_1 - 1.2e-07 32.0 0.2 2.1e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Prion PF00377.16 001279818.1_36222001_1 - 1.2e-35 121.7 4.6 1.5e-35 121.4 4.6 1.1 1 0 0 1 1 1 1 Prion/Doppel alpha-helical domain Prion_bPrPp PF11587.6 001279818.1_36222001_1 - 3.5e-17 61.8 1.0 6.8e-17 60.9 1.0 1.5 1 0 0 1 1 1 1 Major prion protein bPrPp - N terminal Prion_octapep PF03991.10 001279818.1_36222001_1 - 0.13 13.0 89.9 1.3 9.9 9.9 7.2 6 0 0 6 6 6 0 Copper binding octapeptide repeat MNSV_P7B PF06692.9 001279818.1_36222001_1 - 3.2 7.7 5.5 10 6.1 0.2 2.6 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Ras PF00071.20 001285685.1_09022001_1 - 2.6e-57 192.8 0.0 3.3e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001285685.1_09022001_1 - 2.6e-23 82.4 0.0 4e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001285685.1_09022001_1 - 1.7e-10 40.5 0.0 3.2e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001285685.1_09022001_1 - 0.00013 21.4 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001285685.1_09022001_1 - 0.029 14.1 0.0 0.13 12.0 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001285685.1_09022001_1 - 0.037 13.3 0.0 0.056 12.7 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001285685.1_09022001_1 - 0.047 13.0 0.0 0.076 12.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TGFb_propeptide PF00688.16 001290858.1_07323001_1 - 1.3e-98 329.5 0.0 1.8e-98 329.1 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 001290858.1_07323001_1 - 3.1e-36 124.3 2.5 5.4e-36 123.5 2.5 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain Ribosomal_L37ae PF01780.17 001290889.1_07321001_3 - 2e-47 159.0 11.2 2.4e-47 158.8 11.2 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rsm1 PF08600.8 001290889.1_07321001_3 - 0.028 14.4 0.7 0.044 13.8 0.7 1.3 1 0 0 1 1 1 0 Rsm1-like Elf1 PF05129.11 001290889.1_07321001_3 - 0.029 14.3 0.4 0.065 13.1 0.3 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.5 001290889.1_07321001_3 - 0.055 13.3 1.6 0.098 12.5 1.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.11 001290889.1_07321001_3 - 0.12 12.1 3.6 0.36 10.6 3.6 1.9 1 1 0 1 1 1 0 ClpX C4-type zinc finger Ras PF00071.20 001290930.1_07322001_1 - 1.1e-53 181.0 0.0 1.3e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001290930.1_07322001_1 - 7.7e-20 71.2 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001290930.1_07322001_1 - 4.4e-08 32.6 0.0 5.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.3 001290930.1_07322001_1 - 0.00037 20.5 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial GTP_EFTU PF00009.25 001290930.1_07322001_1 - 0.0051 16.2 0.1 0.023 14.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Hormone_1 PF00103.18 001290929.1_07322001_1 - 2.9e-47 161.1 0.0 3.3e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family XTBD PF11952.6 001290929.1_07322001_1 - 0.031 13.9 0.0 0.2 11.3 0.0 2.2 2 1 0 2 2 2 0 XRN-Two Binding Domain, XTBD AhpC-TSA PF00578.19 001290946.1_07322001_2 - 1.4e-40 137.9 0.0 2.2e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.7 001290946.1_07322001_2 - 6.6e-15 54.6 0.1 1.1e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.8 001290946.1_07322001_2 - 8e-15 54.7 0.0 1.1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Endothelin PF00322.15 001290946.1_07322001_2 - 0.22 11.0 0.7 0.42 10.1 0.7 1.5 1 0 0 1 1 1 0 Endothelin family Asp_protease_2 PF13650.4 001291096.1_35729001_2 - 0.00077 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291096.1_35729001_2 - 0.011 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291096.1_35729001_2 - 0.051 14.0 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291096.1_35729001_3 - 5e-15 55.2 0.0 9.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291096.1_35729001_3 - 1.2e-14 54.3 1.9 5e-14 52.2 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001291096.1_35729001_3 - 0.00034 20.6 0.1 0.00065 19.7 0.1 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291096.1_35729001_3 - 0.0019 17.9 4.7 0.0033 17.2 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291096.1_35729001_3 - 0.0029 17.1 0.2 0.0064 16.0 0.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291096.1_35729001_3 - 0.0066 16.2 0.4 0.011 15.5 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 ZapB PF06005.10 001291096.1_35729001_3 - 0.23 11.8 9.2 0.68 10.3 9.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapB CENP-H PF05837.10 001291096.1_35729001_3 - 0.25 11.6 5.4 0.47 10.8 4.8 1.7 2 0 0 2 2 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001291096.1_35729001_3 - 0.32 11.5 3.8 0.79 10.3 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CCDC106 PF15794.3 001291096.1_35729001_3 - 0.36 10.4 4.1 0.55 9.8 2.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Spc7 PF08317.9 001291096.1_35729001_3 - 0.37 9.5 3.4 0.65 8.7 3.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.3 001291096.1_35729001_3 - 0.4 10.9 3.9 0.68 10.2 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) SlyX PF04102.10 001291096.1_35729001_3 - 0.49 10.9 2.6 1.4 9.4 2.6 1.8 1 0 0 1 1 1 0 SlyX LPP PF04728.11 001291096.1_35729001_3 - 0.66 10.3 2.1 1.3 9.4 2.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper SHE3 PF17078.3 001291096.1_35729001_3 - 0.73 9.4 7.3 1.6 8.3 7.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001291096.1_35729001_3 - 1.1 9.0 5.9 2.3 7.9 5.9 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001291096.1_35729001_3 - 1.3 9.0 8.4 3.3 7.7 8.4 1.7 1 0 0 1 1 1 0 bZIP transcription factor TMF_DNA_bd PF12329.6 001291096.1_35729001_3 - 1.5 8.7 6.5 3.8 7.4 6.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.12 001291096.1_35729001_3 - 1.6 8.3 5.3 3.2 7.4 5.3 1.4 1 0 0 1 1 1 0 IncA protein GIT_CC PF16559.3 001291096.1_35729001_3 - 1.8 8.5 7.1 5.2 7.0 7.1 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291096.1_35729001_3 - 5.5 7.2 7.5 39 4.5 7.5 2.3 1 1 0 1 1 1 0 TSC-22/dip/bun family Asp_protease_2 PF13650.4 001291098.1_37429001_1 - 0.00033 21.1 0.0 0.00057 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291098.1_37429001_1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291098.1_37429001_1 - 0.048 14.1 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CAP_N PF01213.17 001291098.1_37429001_1 - 6.8 5.9 10.7 14 4.9 10.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Retrotrans_gag PF03732.15 001291098.1_37429001_2 - 3.1e-15 56.1 3.5 6.6e-15 55.1 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291098.1_37429001_2 - 2.4e-14 53.0 0.0 4.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291098.1_37429001_2 - 0.00029 20.6 5.0 0.00051 19.8 5.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291098.1_37429001_2 - 0.0021 17.6 0.2 0.0049 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger IncA PF04156.12 001291098.1_37429001_2 - 0.0091 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 IncA protein Rootletin PF15035.4 001291098.1_37429001_2 - 0.05 13.5 8.0 0.09 12.7 8.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CCDC106 PF15794.3 001291098.1_37429001_2 - 0.084 12.4 1.4 0.19 11.2 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 zf-CCHC PF00098.21 001291098.1_37429001_2 - 0.09 12.8 2.2 0.35 10.9 2.2 2.1 1 0 0 1 1 1 0 Zinc knuckle DUF1664 PF07889.10 001291098.1_37429001_2 - 0.24 11.2 0.6 0.43 10.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.3 001291098.1_37429001_2 - 0.31 11.0 4.3 0.69 9.9 4.3 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation SHE3 PF17078.3 001291098.1_37429001_2 - 0.34 10.4 6.8 0.72 9.4 6.8 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CENP-H PF05837.10 001291098.1_37429001_2 - 0.35 11.2 3.7 0.83 9.9 3.7 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001291098.1_37429001_2 - 0.38 11.3 3.9 0.88 10.1 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001291098.1_37429001_2 - 0.81 8.4 7.0 1.4 7.6 7.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.10 001291098.1_37429001_2 - 0.84 10.0 10.4 2 8.8 10.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.13 001291098.1_37429001_2 - 1.4 8.6 5.9 3.7 7.2 5.9 1.7 1 0 0 1 1 1 0 Septum formation initiator Mito_fiss_reg PF05308.9 001291098.1_37429001_2 - 1.7 8.5 5.4 3.2 7.6 5.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3450 PF11932.6 001291098.1_37429001_2 - 2 7.5 5.8 3.6 6.7 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.19 001291098.1_37429001_2 - 2.1 8.4 9.7 5.6 7.0 9.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor SlyX PF04102.10 001291098.1_37429001_2 - 2.4 8.7 5.8 5.9 7.5 5.8 1.6 1 0 0 1 1 1 0 SlyX APG6 PF04111.10 001291098.1_37429001_2 - 3.9 6.6 6.0 7.2 5.8 6.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GIT_CC PF16559.3 001291098.1_37429001_2 - 4 7.4 8.2 10 6.1 8.2 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CAP_N PF01213.17 001291098.1_37429001_2 - 8.9 5.5 8.0 16 4.7 8.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Asp_protease_2 PF13650.4 001291099.1_52229001_1 - 0.00034 21.1 0.0 0.00058 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291099.1_52229001_1 - 0.015 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291099.1_52229001_1 - 0.054 13.9 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CAP_N PF01213.17 001291099.1_52229001_1 - 7 5.9 10.7 14 4.9 10.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Retrotrans_gag PF03732.15 001291099.1_52229001_2 - 4.3e-15 55.6 3.6 6.6e-15 55.1 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291099.1_52229001_2 - 2.3e-14 53.1 0.0 4.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291099.1_52229001_2 - 0.0015 18.3 5.8 0.0026 17.5 5.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291099.1_52229001_2 - 0.0021 17.6 0.2 0.0049 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291099.1_52229001_2 - 0.053 13.5 7.9 0.097 12.6 7.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.12 001291099.1_52229001_2 - 0.091 12.4 2.9 0.17 11.6 2.9 1.3 1 0 0 1 1 1 0 IncA protein zf-CCHC PF00098.21 001291099.1_52229001_2 - 0.11 12.5 2.2 0.35 10.9 2.2 2.0 1 0 0 1 1 1 0 Zinc knuckle CCDC106 PF15794.3 001291099.1_52229001_2 - 0.11 12.0 1.4 0.19 11.2 1.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001291099.1_52229001_2 - 0.35 11.1 3.7 0.83 9.9 3.7 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.3 001291099.1_52229001_2 - 0.37 10.8 4.3 0.69 9.9 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation SHE3 PF17078.3 001291099.1_52229001_2 - 0.39 10.3 6.9 0.82 9.2 6.9 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.9 001291099.1_52229001_2 - 0.55 8.9 6.0 0.95 8.1 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291099.1_52229001_2 - 0.72 10.4 4.7 1.7 9.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291099.1_52229001_2 - 0.82 10.0 10.4 2 8.8 10.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.19 001291099.1_52229001_2 - 0.85 9.6 8.2 2.2 8.3 8.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.13 001291099.1_52229001_2 - 1.6 8.4 5.9 4.2 7.1 5.9 1.7 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291099.1_52229001_2 - 1.8 8.5 7.1 4.7 7.2 7.1 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291099.1_52229001_2 - 2.4 8.7 5.8 5.7 7.5 5.8 1.6 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291099.1_52229001_2 - 2.9 7.0 5.3 4.9 6.2 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.6 001291099.1_52229001_2 - 3.5 7.6 8.2 6.4 6.7 8.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Asp_protease_2 PF13650.4 001291100.1_52229001_1 - 0.00034 21.1 0.0 0.00058 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291100.1_52229001_1 - 0.015 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291100.1_52229001_1 - 0.054 13.9 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CAP_N PF01213.17 001291100.1_52229001_1 - 7 5.9 10.7 14 4.9 10.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Retrotrans_gag PF03732.15 001291100.1_52229001_2 - 4.3e-15 55.6 3.6 6.6e-15 55.1 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291100.1_52229001_2 - 2.3e-14 53.1 0.0 4.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291100.1_52229001_2 - 0.0015 18.3 5.8 0.0026 17.5 5.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291100.1_52229001_2 - 0.0021 17.6 0.2 0.0049 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291100.1_52229001_2 - 0.053 13.5 7.9 0.097 12.6 7.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.12 001291100.1_52229001_2 - 0.091 12.4 2.9 0.17 11.6 2.9 1.3 1 0 0 1 1 1 0 IncA protein zf-CCHC PF00098.21 001291100.1_52229001_2 - 0.11 12.5 2.2 0.35 10.9 2.2 2.0 1 0 0 1 1 1 0 Zinc knuckle CCDC106 PF15794.3 001291100.1_52229001_2 - 0.11 12.0 1.4 0.19 11.2 1.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001291100.1_52229001_2 - 0.35 11.1 3.7 0.83 9.9 3.7 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.3 001291100.1_52229001_2 - 0.37 10.8 4.3 0.69 9.9 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation SHE3 PF17078.3 001291100.1_52229001_2 - 0.39 10.3 6.9 0.82 9.2 6.9 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.9 001291100.1_52229001_2 - 0.55 8.9 6.0 0.95 8.1 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.11 001291100.1_52229001_2 - 0.72 10.4 4.7 1.7 9.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001291100.1_52229001_2 - 0.82 10.0 10.4 2 8.8 10.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.19 001291100.1_52229001_2 - 0.85 9.6 8.2 2.2 8.3 8.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.13 001291100.1_52229001_2 - 1.6 8.4 5.9 4.2 7.1 5.9 1.7 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291100.1_52229001_2 - 1.8 8.5 7.1 4.7 7.2 7.1 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.10 001291100.1_52229001_2 - 2.4 8.7 5.8 5.7 7.5 5.8 1.6 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291100.1_52229001_2 - 2.9 7.0 5.3 4.9 6.2 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.6 001291100.1_52229001_2 - 3.5 7.6 8.2 6.4 6.7 8.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4939 PF16297.3 001291103.1_51329001_1 - 7e-15 54.8 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291103.1_51329001_1 - 5e-14 52.2 2.9 1.4e-13 50.8 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001291103.1_51329001_1 - 0.00039 20.4 0.5 0.00078 19.4 0.1 1.6 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291103.1_51329001_1 - 0.001 18.8 5.6 0.0017 18.1 5.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291103.1_51329001_1 - 0.0062 16.1 0.2 0.014 15.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291103.1_51329001_1 - 0.039 13.7 0.5 0.063 13.0 0.5 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF737 PF05300.9 001291103.1_51329001_1 - 0.11 12.7 3.5 0.19 11.9 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ZapB PF06005.10 001291103.1_51329001_1 - 0.12 12.7 8.2 0.3 11.4 8.2 1.6 1 0 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.10 001291103.1_51329001_1 - 0.14 12.7 1.6 0.32 11.5 1.6 1.6 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291103.1_51329001_1 - 0.18 11.0 6.1 0.31 10.2 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.12 001291103.1_51329001_1 - 0.24 11.0 4.5 0.44 10.2 4.5 1.3 1 0 0 1 1 1 0 IncA protein SHE3 PF17078.3 001291103.1_51329001_1 - 0.3 10.6 5.6 0.62 9.6 5.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.3 001291103.1_51329001_1 - 0.3 11.0 4.3 0.56 10.2 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Uso1_p115_C PF04871.11 001291103.1_51329001_1 - 0.38 11.0 6.3 0.64 10.3 6.3 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF972 PF06156.11 001291103.1_51329001_1 - 0.51 10.8 3.7 1.2 9.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.13 001291103.1_51329001_1 - 0.97 9.1 4.6 2.4 7.9 4.6 1.6 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.9 001291103.1_51329001_1 - 1 8.1 5.9 1.7 7.3 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.10 001291103.1_51329001_1 - 1.2 9.5 4.9 2.4 8.4 4.9 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.6 001291103.1_51329001_1 - 1.6 8.6 8.6 3.1 7.7 8.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.3 001291103.1_51329001_1 - 3.6 7.6 7.4 9.4 6.2 7.4 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Asp_protease_2 PF13650.4 001291103.1_51329001_3 - 0.00038 21.0 0.0 0.0006 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291103.1_51329001_3 - 0.041 13.7 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291103.1_51329001_3 - 0.068 13.6 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291313.1_40029001_1 - 3.3e-15 56.0 2.6 4.5e-15 55.6 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291313.1_40029001_1 - 7.6e-15 54.6 0.0 1.3e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.4 001291313.1_40029001_1 - 0.0019 17.7 0.2 0.0048 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger KASH_CCD PF14662.4 001291313.1_40029001_1 - 0.015 15.1 4.9 0.024 14.4 4.9 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001291313.1_40029001_1 - 0.056 13.4 6.4 0.1 12.6 6.4 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.10 001291313.1_40029001_1 - 0.24 11.3 4.6 0.42 10.5 4.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SHE3 PF17078.3 001291313.1_40029001_1 - 0.32 10.6 5.3 0.53 9.8 5.3 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.19 001291313.1_40029001_1 - 0.33 11.0 5.2 0.88 9.6 5.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.11 001291313.1_40029001_1 - 0.64 10.5 3.7 1.4 9.4 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001291313.1_40029001_1 - 0.75 8.5 4.2 1.3 7.7 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mito_fiss_reg PF05308.9 001291313.1_40029001_1 - 0.78 9.6 5.4 1.5 8.7 5.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator ZapB PF06005.10 001291313.1_40029001_1 - 1.5 9.2 9.4 3.2 8.1 9.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.13 001291313.1_40029001_1 - 6 6.6 4.9 14 5.4 4.9 1.5 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.16 001291313.1_40029001_1 - 9.7 6.5 7.0 69 3.7 7.0 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family Asp_protease_2 PF13650.4 001291313.1_40029001_3 - 0.00064 20.2 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291313.1_40029001_3 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291313.1_40029001_3 - 0.059 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001291378.1_28829001_1 - 0.00033 21.2 0.0 0.00058 20.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291378.1_28829001_1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291378.1_28829001_1 - 0.053 14.0 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001291378.1_28829001_2 - 6.2e-15 55.1 3.3 6.6e-15 55.1 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001291378.1_28829001_2 - 1.8e-14 53.5 0.0 3.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) KASH_CCD PF14662.4 001291378.1_28829001_2 - 0.00084 19.1 4.1 0.0016 18.2 4.1 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291378.1_28829001_2 - 0.0021 17.6 0.2 0.0049 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Rootletin PF15035.4 001291378.1_28829001_2 - 0.051 13.5 7.5 0.089 12.7 7.5 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion zf-CCHC PF00098.21 001291378.1_28829001_2 - 0.1 12.6 2.2 0.35 10.9 2.2 2.0 1 0 0 1 1 1 0 Zinc knuckle bZIP_1 PF00170.19 001291378.1_28829001_2 - 0.18 11.8 7.2 0.56 10.2 7.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor CENP-H PF05837.10 001291378.1_28829001_2 - 0.28 11.5 3.0 0.71 10.2 3.0 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SHE3 PF17078.3 001291378.1_28829001_2 - 0.31 10.6 6.6 0.64 9.6 6.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ZapB PF06005.10 001291378.1_28829001_2 - 0.5 10.7 9.7 1.2 9.5 9.7 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001291378.1_28829001_2 - 0.58 10.7 4.2 1.3 9.5 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CCDC106 PF15794.3 001291378.1_28829001_2 - 0.62 9.6 3.7 0.27 10.8 1.4 1.5 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 106 IncA PF04156.12 001291378.1_28829001_2 - 0.8 9.3 5.9 1.5 8.5 5.9 1.3 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.9 001291378.1_28829001_2 - 1.1 7.9 6.5 2 7.1 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.10 001291378.1_28829001_2 - 2 9.0 5.8 6.1 7.4 5.8 1.8 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.6 001291378.1_28829001_2 - 2.4 7.2 5.2 4.1 6.5 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.13 001291378.1_28829001_2 - 3.5 7.3 7.4 8.6 6.1 7.4 1.6 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.3 001291378.1_28829001_2 - 6.7 6.7 7.6 16 5.5 7.6 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.16 001291378.1_28829001_2 - 8.2 6.7 6.5 36 4.6 6.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family Orn_Arg_deC_N PF02784.14 001291782.1_42228001_2 - 5.6e-64 215.8 0.1 7.1e-64 215.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291782.1_42228001_2 - 3.2e-24 85.0 0.0 6.3e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF4939 PF16297.3 001292094.1_37829001_1 - 5.5e-15 55.1 0.0 1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001292094.1_37829001_1 - 6.4e-14 51.9 3.0 1.4e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein KASH_CCD PF14662.4 001292094.1_37829001_1 - 0.0002 21.1 6.8 0.00033 20.4 6.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.4 001292094.1_37829001_1 - 0.00038 20.5 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion zf-CCHC_5 PF14787.4 001292094.1_37829001_1 - 0.0055 16.2 0.2 0.014 15.0 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001292094.1_37829001_1 - 0.0098 15.6 0.6 0.016 14.9 0.6 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 IncA PF04156.12 001292094.1_37829001_1 - 0.016 14.9 0.7 0.029 14.0 0.7 1.3 1 0 0 1 1 1 0 IncA protein DUF737 PF05300.9 001292094.1_37829001_1 - 0.053 13.7 2.0 0.094 12.9 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ZapB PF06005.10 001292094.1_37829001_1 - 0.12 12.7 8.1 0.26 11.6 8.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.10 001292094.1_37829001_1 - 0.13 12.7 1.6 0.32 11.5 1.6 1.6 1 0 0 1 1 1 0 SlyX ERM PF00769.17 001292094.1_37829001_1 - 0.22 11.2 7.7 0.38 10.4 7.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.3 001292094.1_37829001_1 - 0.31 11.0 4.3 0.56 10.2 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF1664 PF07889.10 001292094.1_37829001_1 - 0.44 10.4 2.0 0.83 9.5 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.11 001292094.1_37829001_1 - 0.45 11.0 3.5 1 9.9 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3450 PF11932.6 001292094.1_37829001_1 - 0.51 9.5 7.1 0.81 8.8 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uso1_p115_C PF04871.11 001292094.1_37829001_1 - 0.56 10.4 7.8 0.92 9.8 7.8 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-H PF05837.10 001292094.1_37829001_1 - 1.1 9.5 4.8 2.4 8.5 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.6 001292094.1_37829001_1 - 1.1 9.1 7.9 2.1 8.3 7.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.9 001292094.1_37829001_1 - 1.3 7.7 6.7 2.2 6.9 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SHE3 PF17078.3 001292094.1_37829001_1 - 1.7 8.2 8.0 0.58 9.7 5.4 1.4 2 0 0 2 2 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001292094.1_37829001_1 - 1.7 8.3 5.2 4.2 7.1 5.2 1.6 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001292094.1_37829001_1 - 1.9 8.5 7.5 5.1 7.1 7.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.3 001292094.1_37829001_1 - 3.7 7.5 7.4 9.4 6.2 7.4 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Asp_protease_2 PF13650.4 001292094.1_37829001_3 - 0.00047 20.7 0.0 0.00078 19.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001292094.1_37829001_3 - 0.012 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001292094.1_37829001_3 - 0.046 14.1 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.4 001292096.1_11729001_2 - 0.00078 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001292096.1_11729001_2 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001292096.1_11729001_2 - 0.053 13.9 0.0 0.086 13.3 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.15 001292096.1_11729001_3 - 5.1e-15 55.4 1.9 1.9e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.3 001292096.1_11729001_3 - 5.3e-15 55.1 0.0 9.4e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Rootletin PF15035.4 001292096.1_11729001_3 - 0.00035 20.6 0.1 0.00066 19.7 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001292096.1_11729001_3 - 0.0021 17.8 4.6 0.0035 17.1 4.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001292096.1_11729001_3 - 0.0031 17.0 0.2 0.0069 15.9 0.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001292096.1_11729001_3 - 0.0082 15.9 0.4 0.014 15.2 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 SlyX PF04102.10 001292096.1_11729001_3 - 0.23 12.0 2.4 0.71 10.4 2.4 1.9 1 0 0 1 1 1 0 SlyX CENP-H PF05837.10 001292096.1_11729001_3 - 0.43 10.9 5.2 0.85 9.9 4.7 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.10 001292096.1_11729001_3 - 0.59 10.5 9.7 1.4 9.3 9.7 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001292096.1_11729001_3 - 0.8 10.2 3.9 2 9.0 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.13 001292096.1_11729001_3 - 3.8 7.2 7.1 8.7 6.1 7.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Orn_Arg_deC_N PF02784.14 001293729.1_36525001_1 - 2.6e-68 230.0 0.0 3.3e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293729.1_36525001_1 - 5.7e-19 68.1 0.0 1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293729.1_36525001_1 - 8.2e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293730.1_10725001_1 - 1.4e-69 234.1 0.0 1.8e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293730.1_10725001_1 - 7.2e-19 67.8 0.0 1.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293730.1_10725001_1 - 6e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293736.1_48825001_2 - 3.4e-66 223.0 0.0 4.2e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293736.1_48825001_2 - 1.4e-18 66.9 0.0 2.9e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293736.1_48825001_2 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293740.1_20325001_2 - 6.5e-71 238.5 0.0 8.1e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293740.1_20325001_2 - 5.4e-22 77.8 0.0 8.4e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293740.1_20325001_2 - 0.00053 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293770.1_06425001_3 - 2.5e-70 236.6 0.0 3.2e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293770.1_06425001_3 - 1.2e-15 57.5 0.0 2.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293770.1_06425001_3 - 6.5e-05 22.3 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293771.1_40024001_1 - 1.6e-70 237.3 0.0 2e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293771.1_40024001_1 - 6.4e-18 64.7 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293771.1_40024001_1 - 0.00013 21.3 0.0 0.0003 20.1 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293786.1_52725001_3 - 1.4e-69 234.2 0.0 1.7e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293786.1_52725001_3 - 3.5e-18 65.6 0.0 6.1e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293786.1_52725001_3 - 5.7e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293787.1_28325001_3 - 5.4e-69 232.2 0.0 6.7e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293787.1_28325001_3 - 1.9e-18 66.5 0.0 3.2e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293787.1_28325001_3 - 4.8e-05 22.7 0.0 9.7e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293789.1_12125001_1 - 6.4e-69 232.0 0.0 8e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293789.1_12125001_1 - 5.2e-20 71.5 0.0 9.4e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293789.1_12125001_1 - 0.00044 19.6 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293790.1_20625001_2 - 8.1e-71 238.2 0.0 1e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293790.1_20625001_2 - 4.4e-21 74.9 0.0 7.3e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293790.1_20625001_2 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293799.1_28825001_1 - 9.1e-69 231.5 0.0 1.1e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293799.1_28825001_1 - 1.6e-17 63.4 0.0 3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293799.1_28825001_1 - 0.0029 16.9 0.0 0.0059 15.9 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001293803.1_37825001_1 - 3.2e-72 242.8 0.0 4e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293803.1_37825001_1 - 3.4e-19 68.8 0.0 5.6e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293803.1_37825001_1 - 2e-06 27.3 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001294178.1_27025001_3 - 1e-71 241.2 0.0 1.2e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001294178.1_27025001_3 - 4.5e-18 65.2 0.0 8.3e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001294178.1_27025001_3 - 1.4e-06 27.8 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001291785.2_05128001_2 - 1.7e-63 214.2 0.1 2.1e-63 213.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291785.2_05128001_2 - 3.5e-24 84.9 0.0 6.3e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain MHC_I PF00129.16 001305895.1_29723001_1 - 9.8e-92 305.3 1.2 1.4e-91 304.8 1.2 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001305895.1_29723001_1 - 7.2e-17 61.5 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001305895.1_29723001_1 - 2.9e-14 52.6 12.0 5.1e-14 51.8 12.0 1.4 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001305895.1_29723001_1 - 4e-05 24.0 0.5 0.0017 18.8 0.2 2.8 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 001305895.1_29723001_1 - 9.9e-05 22.2 0.1 0.00022 21.1 0.1 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001305895.1_29723001_1 - 0.015 15.4 0.1 0.046 13.8 0.1 1.8 2 0 0 2 2 2 0 Immunoglobulin domain ig PF00047.23 001305904.1_29723001_1 - 1.2e-30 105.4 0.0 1.9e-11 43.8 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001305904.1_29723001_1 - 2.3e-18 66.2 0.1 5.8e-08 32.8 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001305904.1_29723001_1 - 4.8e-16 59.0 0.0 0.00013 22.4 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001305904.1_29723001_1 - 6e-08 32.7 1.8 2.9 8.0 0.0 5.1 4 2 1 6 6 6 3 Immunoglobulin V-set domain Lep_receptor_Ig PF06328.9 001305904.1_29723001_1 - 0.087 12.7 0.0 5.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Ig-like C2-type domain Ald_Xan_dh_C2 PF02738.16 001308455.1_39429001_1 - 8.2e-180 598.7 0.0 1.1e-179 598.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001308455.1_39429001_1 - 1.5e-41 141.8 0.0 3e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001308455.1_39429001_1 - 1.8e-31 108.6 1.9 4.1e-31 107.5 1.4 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001308455.1_39429001_1 - 4.1e-30 103.4 0.3 1.1e-29 102.0 0.3 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001308455.1_39429001_1 - 1.6e-27 95.5 0.1 5.4e-26 90.6 0.0 2.9 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001308455.1_39429001_1 - 4.2e-08 32.9 0.7 4.7e-07 29.5 0.1 2.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.15 001308455.1_39429001_1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 DUF218 domain Urease_beta PF00699.18 001308455.1_39429001_1 - 0.085 12.8 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Urease beta subunit CARD_2 PF16739.3 001308672.1_35724001_1 - 1.4e-18 66.5 0.0 2e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Caspase recruitment domain MHC_II_beta PF00969.17 001309030.1_29722001_1 - 5.5e-29 100.0 0.6 9.7e-29 99.2 0.6 1.4 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001309030.1_29722001_1 - 2.7e-27 94.9 0.1 1.2e-26 92.9 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001309030.1_29722001_1 - 0.00022 21.6 0.0 0.00075 19.9 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001309030.1_29722001_1 - 0.00066 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.13 001309030.1_29722001_1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Marek's disease glycoprotein A Ig_2 PF13895.4 001309030.1_29722001_1 - 0.002 18.3 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001309030.1_29722001_1 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain PTEN_C2 PF10409.7 001301760.1_39624001_1 - 5.6e-47 158.8 2.5 8.2e-47 158.2 2.5 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.18 001301760.1_39624001_1 - 6.6e-08 32.3 0.0 3.1e-07 30.1 0.0 2.0 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001301760.1_39624001_1 - 0.00015 21.2 0.0 0.00043 19.8 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.4 001301760.1_39624001_1 - 0.0033 17.3 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.4 001301760.1_39624001_1 - 0.0072 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF3256 PF11644.6 001301760.1_39624001_1 - 0.021 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) PV-1 PF06637.9 001319556.1_29523001_1 - 1e-254 845.1 15.8 1.1e-254 844.9 15.8 1.0 1 0 0 1 1 1 1 PV-1 protein (PLVAP) DUF4050 PF13259.4 001319556.1_29523001_1 - 0.042 14.0 2.7 0.087 13.0 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) FA_desaturase PF00487.22 001319797.1_07323001_1 - 2.1e-34 119.4 24.8 2.1e-34 119.4 24.8 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.26 001319797.1_07323001_1 - 3.4e-19 68.6 0.0 6.1e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TNF PF00229.16 001319880.1_08522001_2 - 2.2e-38 130.9 0.0 3.4e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family 7tm_1 PF00001.19 001319792.1_46224001_1 - 1.7e-48 165.0 24.6 2.8e-48 164.4 24.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001319792.1_46224001_1 - 8.3e-11 41.6 21.2 1.1e-10 41.3 21.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001319792.1_46224001_1 - 1.6e-10 40.6 17.2 1.6e-10 40.6 17.2 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001319792.1_46224001_1 - 0.00055 19.6 16.7 0.012 15.2 16.7 2.1 1 1 0 1 1 1 1 Olfactory receptor Git3 PF11710.6 001319792.1_46224001_1 - 1.4 8.5 24.2 0.052 13.2 18.0 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Orn_Arg_deC_N PF02784.14 001308118.1_42726001_2 - 9.8e-60 201.9 0.0 1.3e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001308118.1_42726001_2 - 3.4e-16 59.2 0.0 8.9e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain HLH PF00010.24 001293112.1_02222001_1 - 1.8e-17 62.9 0.3 3.2e-17 62.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF773 PF05600.10 001293112.1_02222001_1 - 0.019 13.6 0.3 0.025 13.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) Dscam_C PF12355.6 001293112.1_02222001_1 - 7.2 7.5 16.1 13 6.7 14.1 2.2 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal Glyco_transf_29 PF00777.16 001293129.1_02223001_1 - 6.9e-37 127.1 0.1 1.9e-36 125.7 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase family 29 (sialyltransferase) PNPase_C PF12111.6 001293129.1_02223001_1 - 0.49 9.7 2.1 0.8 9.1 0.4 2.2 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal zf-AN1 PF01428.14 001293125.1_02227001_1 - 6.6e-08 32.5 7.9 2.2e-07 30.8 7.9 2.0 1 0 0 1 1 1 1 AN1-like Zinc finger zf-A20 PF01754.14 001293125.1_02227001_1 - 8.1e-05 22.3 6.5 8.1e-05 22.3 6.5 2.4 2 0 0 2 2 2 1 A20-like zinc finger Ion_trans PF00520.29 001293124.1_02229001_1 - 4.7e-257 847.9 106.0 2.6e-80 269.0 17.6 4.2 4 0 0 4 4 4 4 Ion transport protein Na_trans_cytopl PF11933.6 001293124.1_02229001_1 - 1.3e-68 231.0 4.7 3.3e-68 229.6 4.7 1.7 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.11 001293124.1_02229001_1 - 2.4e-56 190.9 2.0 2.4e-56 190.9 2.0 3.0 2 1 0 2 2 2 1 Sodium ion transport-associated PKD_channel PF08016.10 001293124.1_02229001_1 - 1.8e-08 33.4 84.1 0.0004 19.1 0.2 9.9 6 4 4 10 10 10 7 Polycystin cation channel GPHH PF16905.3 001293124.1_02229001_1 - 1.3e-05 24.8 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.25 001293124.1_02229001_1 - 0.018 14.7 0.6 0.048 13.3 0.6 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Lustrin_cystein PF14625.4 001293124.1_02229001_1 - 0.087 13.1 0.7 0.29 11.4 0.7 1.8 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain TMEM51 PF15345.4 001293124.1_02229001_1 - 0.7 9.6 8.2 4.8 6.8 0.5 2.7 2 0 0 2 2 2 0 Transmembrane protein 51 Tmemb_9 PF05434.9 001293124.1_02229001_1 - 3.5 7.3 6.1 18 5.0 0.1 3.9 4 0 0 4 4 4 0 TMEM9 FLO_LFY PF01698.14 001293124.1_02229001_1 - 9.6 5.2 12.2 25 3.8 12.2 1.6 1 0 0 1 1 1 0 Floricaula / Leafy protein RNase_H PF00075.22 001286008.1_02223001_3 - 2.8e-44 150.7 0.1 5.1e-44 149.8 0.1 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001286008.1_02223001_3 - 8.6e-19 67.5 3.9 1.9e-18 66.4 3.9 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001286008.1_02223001_3 - 0.0012 18.4 0.0 0.0074 15.9 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase-like COesterase PF00135.26 001291390.1_02226001_1 - 2e-198 660.3 0.0 2.5e-198 660.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001291390.1_02226001_1 - 3.2e-07 30.3 0.2 2.2e-06 27.5 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Filament PF00038.19 001293119.1_02223001_1 - 5.3e-106 354.6 30.0 6.5e-106 354.3 30.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.10 001293119.1_02223001_1 - 0.0034 17.3 4.6 0.0034 17.3 4.6 3.8 2 2 1 3 3 3 1 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.9 001293119.1_02223001_1 - 0.04 13.5 5.3 0.028 14.0 2.3 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.10 001293119.1_02223001_1 - 0.057 13.3 7.9 1.5 8.7 0.2 3.4 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.15 001293119.1_02223001_1 - 0.058 13.2 9.8 1.4 8.7 0.9 4.0 4 1 0 4 4 4 0 Prefoldin subunit CVNH PF08881.8 001293119.1_02223001_1 - 0.077 13.6 2.2 0.44 11.1 0.3 2.9 1 1 1 2 2 2 0 CVNH domain DUF2730 PF10805.6 001293119.1_02223001_1 - 0.093 12.7 4.9 0.69 9.9 1.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) ADIP PF11559.6 001293119.1_02223001_1 - 0.23 11.4 25.8 0.095 12.6 8.8 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.10 001293119.1_02223001_1 - 0.27 10.4 3.8 0.44 9.8 1.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Lzipper-MIP1 PF14389.4 001293119.1_02223001_1 - 0.5 10.5 13.7 0.15 12.2 1.9 3.7 4 1 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF342 PF03961.11 001293119.1_02223001_1 - 0.53 8.7 10.6 0.81 8.1 8.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Tropomyosin_1 PF12718.5 001293119.1_02223001_1 - 0.7 9.9 19.5 0.069 13.2 6.8 3.4 3 0 0 3 3 3 0 Tropomyosin like Sec2p PF06428.9 001293119.1_02223001_1 - 1.1 9.2 14.6 4.1 7.3 3.3 4.0 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Macoilin PF09726.7 001293119.1_02223001_1 - 2.5 6.4 17.9 15 3.9 17.1 2.0 1 1 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.7 001293119.1_02223001_1 - 2.8 7.2 22.2 2.4 7.4 10.8 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Fez1 PF06818.13 001293119.1_02223001_1 - 3.7 7.8 22.3 0.064 13.6 7.2 2.8 1 1 1 2 2 2 0 Fez1 DUF641 PF04859.10 001293119.1_02223001_1 - 4.5 7.5 18.2 2.5 8.3 3.1 3.6 2 2 1 3 3 3 0 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.7 001293119.1_02223001_1 - 7.1 6.7 27.3 0.58 10.2 5.9 3.5 2 2 2 4 4 4 0 JNK_SAPK-associated protein-1 TBPIP PF07106.11 001293119.1_02223001_1 - 8 6.1 20.3 0.07 12.8 8.0 3.0 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Filament PF00038.19 001293120.1_02223001_1 - 4.4e-104 348.3 28.3 5e-104 348.1 28.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.10 001293120.1_02223001_1 - 5.7e-06 26.3 3.0 5.7e-06 26.3 3.0 3.4 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.7 001293120.1_02223001_1 - 0.00082 19.3 35.6 0.0016 18.4 7.4 4.6 2 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SPATA1_C PF15743.3 001293120.1_02223001_1 - 0.022 14.7 0.3 0.022 14.7 0.3 3.5 2 1 0 2 2 1 0 Spermatogenesis-associated C-terminus DUF2746 PF10874.6 001293120.1_02223001_1 - 0.11 12.8 3.5 0.62 10.4 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) DUF972 PF06156.11 001293120.1_02223001_1 - 0.17 12.4 24.4 2.1 8.9 0.2 5.6 2 2 4 6 6 6 0 Protein of unknown function (DUF972) RasGAP_C PF03836.13 001293120.1_02223001_1 - 0.34 11.0 10.0 1.3 9.1 0.4 3.3 2 1 1 3 3 3 0 RasGAP C-terminus Laminin_II PF06009.10 001293120.1_02223001_1 - 0.42 10.5 12.7 3.3 7.6 2.2 4.0 2 2 2 4 4 4 0 Laminin Domain II Phage_GP20 PF06810.9 001293120.1_02223001_1 - 2.3 7.9 14.5 0.2 11.3 3.3 3.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.5 001293120.1_02223001_1 - 3.1 7.8 26.8 2.3 8.2 1.8 3.4 3 0 0 3 3 3 0 Tropomyosin like DUF4349 PF14257.4 001293120.1_02223001_1 - 3.2 7.1 8.3 0.28 10.5 3.1 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) Jnk-SapK_ap_N PF09744.7 001293120.1_02223001_1 - 3.4 7.7 29.3 2 8.5 4.5 3.8 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 FlxA PF14282.4 001293120.1_02223001_1 - 3.5 7.5 22.2 1.7 8.6 6.8 4.2 2 2 1 4 4 4 0 FlxA-like protein DUF4407 PF14362.4 001293120.1_02223001_1 - 5.1 6.2 15.9 0.77 8.9 2.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF724 PF05266.12 001293120.1_02223001_1 - 8 6.1 19.8 3.1 7.4 0.7 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF724) Kinetocho_Slk19 PF12709.5 001293120.1_02223001_1 - 9.3 6.6 21.8 2.2 8.7 0.9 4.9 3 3 2 5 5 5 0 Central kinetochore-associated VWD PF00094.23 001302556.1_02229001_1 - 7.8e-119 393.3 20.2 2.6e-36 125.1 1.1 4.3 4 0 0 4 4 4 4 von Willebrand factor type D domain C8 PF08742.9 001302556.1_02229001_1 - 5.8e-55 183.5 44.1 9.7e-20 70.6 1.1 8.2 5 0 0 5 5 5 3 C8 domain TIL PF01826.15 001302556.1_02229001_1 - 7.5e-27 93.2 67.8 1.4e-12 47.5 17.1 29.8 17 3 8 25 25 25 3 Trypsin Inhibitor like cysteine rich domain TILa PF12714.5 001302556.1_02229001_1 - 4e-19 68.2 503.0 2.4e-10 40.1 7.2 50.6 28 16 23 51 51 51 32 TILa domain FOLN PF09289.8 001302556.1_02229001_1 - 0.00035 20.6 11.1 0.00079 19.4 3.1 39.9 44 0 0 44 44 44 14 Follistatin/Osteonectin-like EGF domain Dynein_light PF01221.16 001302556.1_02229001_1 - 0.14 12.4 0.2 0.89 9.8 0.0 2.4 2 0 0 2 2 2 0 Dynein light chain type 1 Amelotin PF15757.3 001328228.1_02223001_2 - 4.8e-24 84.9 20.8 3.1e-22 79.0 15.5 2.4 2 1 0 2 2 2 2 Amelotin Amelin PF05111.10 001328227.1_02224001_1 - 2.6e-61 207.9 25.3 3.5e-61 207.5 25.3 1.1 1 0 0 1 1 1 1 Ameloblastin precursor (Amelin) PI3K_P85_iSH2 PF16454.3 001328241.1_15725001_3 - 3.8e-61 205.2 21.0 6.1e-61 204.6 21.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.22 001328241.1_15725001_3 - 8e-41 137.8 0.1 3e-20 71.9 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.25 001328241.1_15725001_3 - 4.7e-15 55.6 0.2 1.8e-13 50.4 0.0 2.7 2 1 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.26 001328241.1_15725001_3 - 0.00031 20.2 0.6 0.00087 18.7 0.0 2.1 2 0 0 2 2 2 1 SH3 domain AAA_13 PF13166.4 001328241.1_15725001_3 - 0.00066 18.3 14.5 0.00093 17.9 14.5 1.1 1 0 0 1 1 1 1 AAA domain Mod_r PF07200.11 001328241.1_15725001_3 - 0.012 15.6 14.8 0.53 10.2 6.3 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SH3_9 PF14604.4 001328241.1_15725001_3 - 0.02 14.6 0.1 0.05 13.3 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.15 001328241.1_15725001_3 - 0.025 14.1 0.0 0.064 12.8 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain Lant_dehydr_C PF14028.4 001328241.1_15725001_3 - 0.041 13.3 0.7 0.066 12.6 0.7 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term RNA_binding PF01877.15 001328241.1_15725001_3 - 0.057 13.6 3.9 0.12 12.5 3.9 1.4 1 0 0 1 1 1 0 RNA binding Laminin_I PF06008.12 001328241.1_15725001_3 - 0.083 12.4 9.5 0.16 11.5 9.5 1.4 1 0 0 1 1 1 0 Laminin Domain I DUF4806 PF16064.3 001328241.1_15725001_3 - 0.44 10.7 2.5 1.6 9.0 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) IncA PF04156.12 001328241.1_15725001_3 - 0.88 9.2 11.5 1.7 8.3 11.5 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.17 001328241.1_15725001_3 - 3 5.5 9.3 4.9 4.8 9.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BRE1 PF08647.9 001328241.1_15725001_3 - 6.6 6.8 13.8 0.45 10.5 3.0 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ZapB PF06005.10 001328241.1_15725001_3 - 9.2 6.7 8.9 5.2 7.5 0.6 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Interfer-bind PF09294.8 001328225.1_02223001_3 - 7.9e-22 77.4 0.9 1.7e-21 76.3 0.0 2.1 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001328225.1_02223001_3 - 3.8e-16 58.7 3.4 5.3e-15 55.0 0.5 2.5 2 0 0 2 2 2 2 Tissue factor V-set_CD47 PF08204.9 001328225.1_02223001_3 - 0.033 14.0 0.6 0.069 13.0 0.6 1.5 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Sushi PF00084.18 001328248.1_15729001_3 - 1e-90 298.1 101.3 2.4e-08 34.4 0.1 18.9 19 0 0 19 19 19 18 Sushi repeat (SCR repeat) Sushi_2 PF09014.8 001328248.1_15729001_3 - 0.0078 16.0 8.2 0.68 9.8 0.2 4.5 4 0 0 4 4 4 2 Beta-2-glycoprotein-1 fifth domain HRM PF02793.20 001328248.1_15729001_3 - 3.6 7.8 81.7 0.06 13.5 0.8 13.6 13 1 1 14 14 14 0 Hormone receptor domain DUF3242 PF11586.6 001328238.1_15724001_1 - 0.024 14.2 4.8 0.023 14.3 3.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3242) Hormone_recep PF00104.28 001297487.1_43024001_1 - 2.7e-36 125.0 2.9 4.1e-36 124.4 2.9 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Oest_recep PF02159.13 001297487.1_43024001_1 - 7.5e-36 123.5 3.4 1.8e-35 122.3 3.4 1.7 1 0 0 1 1 1 1 Oestrogen receptor zf-C4 PF00105.16 001297487.1_43024001_1 - 3.6e-31 107.3 13.9 6.5e-31 106.5 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Ald_Xan_dh_C2 PF02738.16 001297448.1_43029001_2 - 8.3e-187 621.8 0.0 1.2e-186 621.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001297448.1_43029001_2 - 7.5e-45 152.6 0.0 1.5e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001297448.1_43029001_2 - 2e-32 111.6 0.1 3.6e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001297448.1_43029001_2 - 5.9e-32 109.3 1.4 1.8e-31 107.8 0.3 2.4 2 0 0 2 2 2 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001297448.1_43029001_2 - 8e-29 99.7 0.0 1.8e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001297448.1_43029001_2 - 1.7e-08 34.2 0.2 1.7e-08 34.2 0.2 2.5 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Pkinase_Tyr PF07714.15 001297466.1_43027001_2 - 5.9e-103 343.5 0.0 9e-103 342.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001297466.1_43027001_2 - 2.5e-42 144.9 0.0 3.9e-28 98.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.4 001297466.1_43027001_2 - 2e-27 95.5 6.2 2e-09 37.8 0.1 6.1 5 1 1 6 6 6 4 Immunoglobulin domain I-set PF07679.14 001297466.1_43027001_2 - 5.2e-22 77.6 0.0 2.1e-08 34.0 0.0 5.1 5 0 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.23 001297466.1_43027001_2 - 3e-15 56.0 0.3 1.7e-05 24.8 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.4 001297466.1_43027001_2 - 3.4e-10 40.0 3.8 0.0037 17.4 0.0 5.6 4 1 1 5 5 5 2 Immunoglobulin domain V-set PF07686.15 001297466.1_43027001_2 - 3.9e-05 23.6 7.2 0.00027 20.9 0.1 5.1 5 2 0 5 5 5 1 Immunoglobulin V-set domain C2-set_2 PF08205.10 001297466.1_43027001_2 - 0.0021 17.9 0.4 0.07 13.1 0.0 3.3 4 0 0 4 4 3 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.13 001297466.1_43027001_2 - 0.027 14.8 0.4 0.24 11.8 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C1-set domain APH PF01636.21 001297466.1_43027001_2 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3817 PF12823.5 001297466.1_43027001_2 - 0.27 12.0 0.8 1.8 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) Ribosomal_S19 PF00203.19 001297462.1_43022001_1 - 9.5e-39 131.0 0.3 1.5e-38 130.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.14 001297462.1_43022001_1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH Ribosomal_L30_N PF08079.10 001297468.1_43022001_2 - 1.1e-27 96.0 12.9 1.1e-27 96.0 12.9 2.4 3 0 0 3 3 3 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.18 001297468.1_43022001_2 - 3.2e-25 87.7 1.0 3.2e-25 87.7 1.0 2.3 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e Pkinase_Tyr PF07714.15 001297470.1_43027001_1 - 2.1e-101 338.4 0.0 3.2e-101 337.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001297470.1_43027001_1 - 1.3e-41 142.6 0.0 6.3e-27 94.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.4 001297470.1_43027001_1 - 6.2e-22 77.9 7.0 7.2e-07 29.6 0.5 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.14 001297470.1_43027001_1 - 1.6e-16 60.0 0.0 0.00023 21.1 0.0 5.7 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.4 001297470.1_43027001_1 - 4.2e-09 36.5 5.6 0.018 15.2 0.2 4.7 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.23 001297470.1_43027001_1 - 1.2e-07 31.7 8.9 4.3e-05 23.5 0.6 5.0 5 1 0 5 5 5 1 Immunoglobulin domain C2-set_2 PF08205.10 001297470.1_43027001_1 - 0.0034 17.3 3.7 0.12 12.3 0.3 3.7 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.15 001297470.1_43027001_1 - 0.0091 16.0 9.8 11 6.1 0.6 6.0 6 1 0 6 6 6 1 Immunoglobulin V-set domain TIM PF00121.16 001328623.1_43023001_2 - 7.4e-86 287.3 0.1 9.1e-86 287.0 0.1 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase HMG_box PF00505.17 001297444.1_43023001_1 - 3.1e-25 88.2 1.0 7.8e-25 87.0 1.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.6 001297444.1_43023001_1 - 5.3e-25 88.2 0.4 5.3e-25 88.2 0.4 3.5 4 0 0 4 4 4 1 Sox developmental protein N terminal HMG_box_2 PF09011.8 001297444.1_43023001_1 - 2.3e-10 40.8 0.7 8e-10 39.1 0.7 2.0 1 0 0 1 1 1 1 HMG-box domain PTPLA PF04387.12 001319338.1_43022001_1 - 2.2e-60 203.0 11.6 3.7e-60 202.3 11.6 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA VHS PF00790.17 001319339.1_43024001_1 - 1.9e-41 141.1 0.5 4.1e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.26 001319339.1_43024001_1 - 1.2e-17 63.1 0.1 2.3e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001319339.1_43024001_1 - 6.1e-13 48.1 0.0 1.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 001319339.1_43024001_1 - 8.5e-13 47.8 0.1 2.1e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.18 001319339.1_43024001_1 - 0.00013 21.5 2.4 0.00029 20.4 2.4 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif GAT PF03127.12 001319339.1_43024001_1 - 0.33 11.2 2.8 0.8 9.9 2.8 1.7 1 0 0 1 1 1 0 GAT domain adh_short PF00106.23 001329062.1_43023001_1 - 1.5e-44 151.7 0.0 2e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001329062.1_43023001_1 - 1.2e-23 83.8 0.0 1.6e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001329062.1_43023001_1 - 0.0028 17.4 0.2 0.0062 16.3 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.19 001329062.1_43023001_1 - 0.0039 16.6 0.4 0.24 10.7 0.2 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ApbA PF02558.14 001329062.1_43023001_1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.16 001329062.1_43023001_1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.4 001329062.1_43023001_1 - 0.18 11.5 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Cyclin_N PF00134.21 001329063.1_43023001_2 - 1.8e-19 69.7 0.3 3.8e-19 68.6 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain IRF-3 PF10401.7 001294228.1_15724001_1 - 1.4e-50 171.5 0.3 1.9e-50 171.0 0.3 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.15 001294228.1_15724001_1 - 1.6e-33 115.0 0.9 2.8e-33 114.2 0.9 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor G_path_suppress PF15991.3 001294228.1_15724001_1 - 0.12 12.3 1.7 0.18 11.8 1.7 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor UQ_con PF00179.24 001294186.1_15724001_3 - 2.9e-47 159.7 0.0 4.2e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001294186.1_15724001_3 - 0.00064 19.3 0.0 0.00099 18.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B V-set_2 PF15910.3 001294233.1_15722001_1 - 0.00027 20.9 0.6 0.00043 20.2 0.6 1.3 1 0 0 1 1 1 1 ICOS V-set domain V-set PF07686.15 001294233.1_15722001_1 - 0.0016 18.4 0.6 0.008 16.2 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain DUF4389 PF14333.4 001294233.1_15722001_1 - 0.0062 16.3 2.1 0.012 15.4 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4389) V-set_CD47 PF08204.9 001294233.1_15722001_1 - 0.035 13.9 0.5 0.098 12.5 0.5 1.7 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Ig_4 PF16680.3 001294233.1_15722001_1 - 0.041 14.1 0.2 0.13 12.5 0.2 1.9 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain RRM_1 PF00076.20 001294234.1_15724001_2 - 6.5e-10 38.6 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001294234.1_15724001_2 - 0.0038 17.2 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif DZF PF07528.12 001294217.1_15726001_2 - 4.5e-59 200.0 0.0 6.3e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 DZF domain dsrm PF00035.24 001294217.1_15726001_2 - 6.1e-22 77.9 0.0 1.5e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif Dicer_dimer PF03368.12 001294217.1_15726001_2 - 0.12 12.5 0.7 27 4.9 0.0 3.4 4 0 0 4 4 4 0 Dicer dimerisation domain Nramp PF01566.16 001319816.1_15728001_2 - 9.9e-122 406.2 11.9 9.9e-122 406.2 11.9 2.0 2 1 1 3 3 3 1 Natural resistance-associated macrophage protein zf-C4 PF00105.16 001294202.1_15727001_1 - 8.9e-32 109.2 11.6 2.4e-31 107.9 11.6 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001294202.1_15727001_1 - 1.1e-28 100.1 3.7 1.8e-28 99.4 3.7 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor CTP_transf_like PF01467.24 001294203.1_15725001_1 - 4e-29 101.5 0.7 6.3e-29 100.9 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like GldM_N PF12081.6 001294203.1_15725001_1 - 0.053 13.5 1.6 0.082 12.9 1.6 1.2 1 0 0 1 1 1 0 GldM N-terminal domain XhlA PF10779.7 001294203.1_15725001_1 - 0.64 10.1 2.5 1.2 9.2 2.5 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Lipase PF00151.17 001319821.1_15725001_3 - 7.9e-111 370.4 0.1 1.1e-110 370.0 0.1 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.21 001319821.1_15725001_3 - 1.6e-13 51.1 0.1 4e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.5 001319821.1_15725001_3 - 0.0002 22.0 0.2 0.00029 21.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001319821.1_15725001_3 - 0.00045 19.8 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold NAGLU PF05089.10 001319821.1_15725001_3 - 0.011 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Zona_pellucida PF00100.21 001294225.1_15724001_2 - 5.4e-39 134.3 0.0 7.6e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain UCR_hinge PF02320.14 001200319.2_26622001_1 - 2e-22 79.0 8.0 2.9e-22 78.5 8.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Hormone_recep PF00104.28 001329339.1_27324001_1 - 3.9e-34 117.9 4.5 5.7e-34 117.4 4.5 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001329339.1_27324001_1 - 2.8e-31 107.6 13.5 4.7e-31 106.9 13.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ERbeta_N PF12497.6 001329339.1_27324001_1 - 5.9e-27 93.6 6.3 1.2e-26 92.5 6.3 1.5 1 0 0 1 1 1 1 Estrogen receptor beta Calsarcin PF05556.9 001329278.1_26623001_2 - 3e-80 269.1 1.8 3.5e-80 268.8 1.8 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) Zona_pellucida PF00100.21 001329333.1_27324001_2 - 1.7e-48 165.5 0.0 2.2e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.16 001329333.1_27324001_2 - 1.3e-05 24.8 6.8 1.3e-05 24.8 6.8 2.4 2 0 0 2 2 2 1 Trefoil (P-type) domain TEX29 PF15839.3 001329333.1_27324001_2 - 2 9.0 6.8 0.68 10.5 3.2 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 29 protein HSP70 PF00012.18 001329345.1_27324001_1 - 2.3e-261 868.1 9.6 2.7e-261 867.9 9.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001329345.1_27324001_1 - 9.5e-17 60.7 0.7 3.9e-15 55.4 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.14 001329345.1_27324001_1 - 0.00081 19.0 0.0 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.4 001329345.1_27324001_1 - 0.0017 18.7 2.2 1.1 9.5 0.1 3.3 3 1 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.18 001329345.1_27324001_1 - 0.033 13.6 0.2 5.7 6.2 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FKBP_N PF01346.16 001329345.1_27324001_1 - 0.2 11.9 6.4 0.22 11.8 4.4 2.1 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase GST_N_3 PF13417.4 001329352.1_27322001_1 - 1.1e-23 83.2 0.0 2.3e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001329352.1_27322001_1 - 2e-16 59.9 0.0 5.5e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001329352.1_27322001_1 - 4.3e-15 55.7 0.1 1.1e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001329352.1_27322001_1 - 6.3e-11 42.2 0.2 1e-10 41.6 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001329352.1_27322001_1 - 1.9e-10 40.4 0.0 3.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001329352.1_27322001_1 - 1.5e-09 37.8 0.4 3e-09 36.8 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 001329352.1_27322001_1 - 0.00023 21.2 0.0 0.00061 19.8 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C_6 PF17171.2 001329352.1_27322001_1 - 0.023 14.4 0.0 0.054 13.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.3 001329352.1_27322001_1 - 0.078 13.4 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAD_binding_7 PF03441.12 001329347.1_27324001_1 - 1.6e-69 233.1 1.7 2.2e-69 232.7 1.7 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.16 001329347.1_27324001_1 - 5.8e-44 149.9 0.0 1.5e-43 148.5 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase AMH_N PF04709.10 001329363.1_27325001_1 - 3.3e-63 213.8 10.5 1.7e-50 172.0 2.7 3.1 3 0 0 3 3 3 3 Anti-Mullerian hormone, N terminal region TGF_beta PF00019.18 001329363.1_27325001_1 - 4.5e-16 59.5 0.2 9.6e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain GHBP PF12772.5 001329341.1_27325001_2 - 3.3e-87 292.7 1.0 5.1e-87 292.1 1.0 1.3 1 0 0 1 1 1 1 Growth hormone receptor binding EpoR_lig-bind PF09067.8 001329341.1_27325001_2 - 1.9e-07 31.1 2.4 4.2e-07 30.0 2.4 1.5 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.19 001329341.1_27325001_2 - 2.2e-05 24.6 0.5 8.2e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III domain Interfer-bind PF09294.8 001329341.1_27325001_2 - 0.06 13.5 0.2 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III IL6Ra-bind PF09240.8 001329341.1_27325001_2 - 0.083 13.2 1.9 0.18 12.1 1.9 1.5 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding TraV PF09676.8 001329341.1_27325001_2 - 6.4 7.6 6.8 2.3 9.1 3.4 1.9 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) EpoR_lig-bind PF09067.8 001329340.1_27326001_2 - 2.7e-21 75.6 0.0 6e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.8 001329340.1_27326001_2 - 4.7e-06 26.8 0.2 1.7e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding fn3 PF00041.19 001329340.1_27326001_2 - 8.5e-05 22.7 4.5 0.0007 19.8 1.5 2.9 3 1 0 3 3 3 1 Fibronectin type III domain Hormone_recep PF00104.28 001329360.1_27325001_3 - 1.7e-36 125.6 4.9 2.7e-36 125.0 4.9 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001329360.1_27325001_3 - 4.5e-31 107.0 14.0 7.6e-31 106.2 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ERbeta_N PF12497.6 001329360.1_27325001_3 - 1.3e-24 86.0 10.8 1.3e-24 86.0 10.8 2.1 2 0 0 2 2 2 1 Estrogen receptor beta ANTH PF07651.14 001329360.1_27325001_3 - 0.076 11.8 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 ANTH domain HSP90 PF00183.16 001329337.1_27325001_1 - 8.3e-242 803.5 34.7 1.1e-241 803.0 34.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.24 001329337.1_27325001_1 - 4.9e-15 55.9 0.1 1.6e-14 54.3 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001329337.1_27325001_1 - 5.9e-12 45.5 0.1 1.6e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1198 PF06711.9 001329337.1_27325001_1 - 0.12 12.4 0.4 0.47 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) Zip PF02535.20 001329337.1_27325001_1 - 0.25 10.4 3.8 0.11 11.6 1.3 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter CDC45 PF02724.12 001329337.1_27325001_1 - 0.26 9.4 17.5 0.54 8.4 17.5 1.5 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.15 001329337.1_27325001_1 - 3.8 6.0 7.9 2.7 6.5 5.4 1.8 2 0 0 2 2 2 0 Presenilin DUF1510 PF07423.9 001329337.1_27325001_1 - 5.5 6.2 33.7 0.24 10.7 25.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FAD_binding_7 PF03441.12 001329338.1_27324001_1 - 2.8e-68 229.1 0.6 5.1e-68 228.2 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.16 001329338.1_27324001_1 - 1.4e-42 145.3 0.0 2.6e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Ras PF00071.20 001329374.1_27323001_3 - 3.4e-52 176.2 0.1 4.3e-52 175.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001329374.1_27323001_3 - 2.7e-19 69.4 0.0 4.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.25 001329374.1_27323001_3 - 1.3e-06 28.0 0.5 2.1e-06 27.3 0.1 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.19 001329374.1_27323001_3 - 4.9e-06 26.0 0.0 7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001329374.1_27323001_3 - 7.4e-05 22.6 0.1 0.051 13.3 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001329374.1_27323001_3 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001329374.1_27323001_3 - 0.02 14.1 0.2 0.027 13.7 0.2 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.15 001329374.1_27323001_3 - 0.044 13.4 0.2 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 7tm_1 PF00001.19 001329358.1_27328001_2 - 1.9e-28 99.3 17.8 3.9e-28 98.3 17.8 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.4 001329358.1_27328001_2 - 2.7e-24 84.5 1.3 1.2e-07 31.3 0.0 4.7 2 2 3 5 5 5 5 Leucine rich repeat LRR_5 PF13306.4 001329358.1_27328001_2 - 3.3e-17 62.5 0.0 4.4e-12 45.9 0.2 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.5 001329358.1_27328001_2 - 1.1e-07 31.9 0.7 0.0081 16.4 0.0 5.4 4 2 3 7 7 7 1 Leucine Rich repeats (2 copies) Comm PF15957.3 001329358.1_27328001_2 - 0.0084 16.3 0.4 0.031 14.5 0.4 2.0 1 0 0 1 1 1 1 Commissureless GST_N PF02798.18 001329343.1_27322001_2 - 1.3e-16 60.5 0.0 3.2e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001329343.1_27322001_2 - 1.1e-13 51.0 0.4 3.3e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001329343.1_27322001_2 - 5.6e-12 45.6 1.1 6.9e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001329343.1_27322001_2 - 0.0083 16.4 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Vitellogenin_N PF01347.20 001329344.1_27329001_1 - 3.6e-160 534.2 6.8 1.1e-158 529.4 0.0 2.2 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.9 001329344.1_27329001_1 - 1.9e-64 217.7 0.0 1.9e-64 217.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1943) DUF1944 PF09175.8 001329344.1_27329001_1 - 9.1e-63 210.9 0.9 2.1e-62 209.7 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) VWD PF00094.23 001329344.1_27329001_1 - 1.1e-25 90.6 1.7 2e-25 89.8 0.3 2.3 2 0 0 2 2 2 1 von Willebrand factor type D domain Apt1 PF10351.7 001329344.1_27329001_1 - 0.31 9.7 21.9 0.67 8.6 21.9 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hormone_1 PF00103.18 001329353.1_27322001_1 - 4.5e-20 72.2 3.1 1.3e-19 70.7 3.1 1.6 1 1 0 1 1 1 1 Somatotropin hormone family PAS_11 PF14598.4 001329351.1_27324001_1 - 5.2e-29 100.5 0.3 8.2e-24 83.8 0.2 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 001329351.1_27324001_1 - 4.8e-23 81.2 0.0 4.6e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.10 001329351.1_27324001_1 - 2.7e-22 78.7 0.0 1.1e-13 51.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.24 001329351.1_27324001_1 - 1.1e-14 53.9 2.3 2.7e-14 52.7 2.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001329351.1_27324001_1 - 7.9e-12 45.2 0.0 8e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001329351.1_27324001_1 - 6.4e-06 26.3 0.0 0.05 13.7 0.0 2.7 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.9 001329351.1_27324001_1 - 0.0059 17.1 0.0 0.053 14.1 0.0 2.2 2 0 0 2 2 2 1 PAS fold Ras PF00071.20 001141632.1_46929001_3 - 3.4e-57 192.4 0.0 4.7e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001141632.1_46929001_3 - 3.2e-20 72.4 0.0 4.8e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001141632.1_46929001_3 - 3.5e-08 33.0 0.0 5.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001141632.1_46929001_3 - 0.00011 21.6 0.0 0.00024 20.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001141632.1_46929001_3 - 0.0007 19.4 0.0 0.47 10.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001141632.1_46929001_3 - 0.00076 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_S3Ae PF01015.16 001292403.1_08122001_3 - 4e-106 353.1 7.7 4.8e-106 352.8 7.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.14 001292403.1_08122001_3 - 0.014 14.8 0.1 0.039 13.4 0.1 1.8 1 1 1 2 2 2 0 Partial alpha/beta-hydrolase lipase region Crystall PF00030.17 001200568.1_26623001_1 - 3.6e-50 168.0 13.0 2.1e-26 91.8 2.3 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001200568.1_26623001_1 - 0.001 18.8 6.4 0.023 14.5 2.6 2.5 2 0 0 2 2 2 2 Peptidase inhibitor family I36 DSPc PF00782.18 001201259.1_26622001_1 - 1.2e-32 112.3 0.0 3e-32 111.1 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001201259.1_26622001_1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.10 001201259.1_26622001_1 - 0.0003 20.9 0.0 0.013 15.6 0.0 2.4 2 1 0 2 2 2 1 Rit1 DUSP-like domain SUI1 PF01253.20 001245942.1_26622001_1 - 1.7e-28 98.8 0.8 2.6e-28 98.2 0.8 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 SH3BGR PF04908.13 001201203.1_26622001_2 - 3.1e-26 91.3 0.1 4e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.22 001201203.1_26622001_2 - 0.0022 18.1 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin AhpC-TSA_2 PF13911.4 001201270.1_26623001_3 - 2.1e-13 50.3 0.1 3.5e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme adh_short PF00106.23 001200383.1_26623001_2 - 2.2e-34 118.5 0.0 1.9e-33 115.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001200383.1_26623001_2 - 1.6e-25 89.9 0.0 9.9e-25 87.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001200383.1_26623001_2 - 2.4e-07 30.7 0.0 3.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001200383.1_26623001_2 - 0.00038 19.9 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family C1q PF00386.19 001292826.1_08124001_2 - 1.1e-30 106.3 0.1 1.8e-30 105.6 0.1 1.4 1 0 0 1 1 1 1 C1q domain Collagen PF01391.16 001292826.1_08124001_2 - 3.2e-10 39.5 36.6 3.4e-05 23.4 22.0 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Ig_5 PF16681.3 001286901.1_41122001_1 - 7.3e-10 39.0 1.9 1.1e-09 38.4 1.9 1.3 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.3 001286901.1_41122001_1 - 1.1e-07 32.0 3.1 1.7e-07 31.3 3.1 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain ITAM PF02189.13 001286901.1_41122001_1 - 0.0031 17.7 0.1 0.0055 17.0 0.1 1.4 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif 7tm_1 PF00001.19 001286322.1_25023001_2 - 5e-16 58.6 14.9 6.5e-16 58.2 14.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Vma12 PF11712.6 001286322.1_25023001_2 - 0.94 9.4 3.2 20 5.1 0.2 2.8 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Laminin_I PF06008.12 001141033.2_46922001_3 - 0.00055 19.6 3.2 0.00071 19.2 3.2 1.1 1 0 0 1 1 1 1 Laminin Domain I Apolipoprotein PF01442.16 001141033.2_46922001_3 - 0.055 13.2 3.6 0.075 12.8 3.6 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ADIP PF11559.6 001141033.2_46922001_3 - 0.092 12.7 5.3 0.13 12.2 5.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.9 001141033.2_46922001_3 - 0.15 10.8 5.0 0.24 10.1 5.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.10 001141033.2_46922001_3 - 0.32 10.2 4.9 0.42 9.8 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.12 001141033.2_46922001_3 - 0.55 9.9 2.8 0.78 9.4 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LRR_8 PF13855.4 001310348.1_02125001_1 - 2.1e-40 136.2 42.6 2e-16 59.4 6.7 8.3 4 3 4 8 8 8 8 Leucine rich repeat TIR PF01582.18 001310348.1_02125001_1 - 1.8e-23 83.1 1.8 2.9e-23 82.5 1.8 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001310348.1_02125001_1 - 1.9e-21 75.6 45.8 0.00018 21.7 4.8 9.2 6 3 4 11 11 11 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001310348.1_02125001_1 - 2.9e-11 43.5 0.0 8e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001310348.1_02125001_1 - 3e-10 39.8 9.6 0.00038 19.9 0.0 4.2 2 2 2 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.4 001310348.1_02125001_1 - 1.2e-05 25.1 0.0 8.4e-05 22.4 0.0 2.4 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_1 PF00560.31 001310348.1_02125001_1 - 0.00013 21.8 41.7 0.09 13.2 0.7 11.9 9 2 0 9 9 9 2 Leucine Rich Repeat DUF1863 PF08937.9 001310348.1_02125001_1 - 0.065 13.4 0.2 0.41 10.8 0.2 2.2 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) LRR_6 PF13516.4 001310348.1_02125001_1 - 0.68 10.0 30.4 2.5 8.2 0.2 9.9 10 0 0 10 10 10 0 Leucine Rich repeat Actin PF00022.17 001286847.1_01524001_1 - 6.4e-151 502.4 0.0 1.7e-150 501.1 0.0 1.6 1 1 0 1 1 1 1 Actin Thioredoxin_7 PF13899.4 001286928.1_41122001_1 - 2.9e-17 62.5 0.0 4.5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.18 001286928.1_41122001_1 - 1.7e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.4 001286928.1_41122001_1 - 0.00055 20.2 0.0 0.00084 19.6 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.13 001286928.1_41122001_1 - 0.0019 18.0 0.1 0.0024 17.7 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_9 PF14595.4 001286928.1_41122001_1 - 0.0055 16.3 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF2973 PF11189.6 001286928.1_41122001_1 - 0.14 12.1 0.0 0.54 10.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2973) Thioredoxin_8 PF13905.4 001286928.1_41122001_1 - 0.16 12.2 0.0 0.6 10.4 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Cys_knot PF00007.20 001286935.1_41122001_2 - 1.1e-29 102.6 13.2 1.4e-29 102.3 13.2 1.1 1 0 0 1 1 1 1 Cystine-knot domain bZIP_Maf PF03131.15 001303986.1_21523001_1 - 1e-06 29.0 8.4 1.4e-06 28.5 8.4 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.19 001303986.1_21523001_1 - 2.5e-05 24.1 13.3 3.5e-05 23.7 13.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001303986.1_21523001_1 - 0.006 16.5 13.6 0.012 15.5 13.6 1.5 1 1 0 1 1 1 1 Basic region leucine zipper LRR_8 PF13855.4 001286933.1_41127001_3 - 2.6e-46 155.1 44.3 5.2e-12 45.2 0.1 9.5 4 3 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.5 001286933.1_41127001_3 - 7.8e-24 83.1 50.5 2.8e-05 24.2 2.9 10.4 5 3 3 10 10 10 8 Leucine Rich repeats (2 copies) TIR PF01582.18 001286933.1_41127001_3 - 3.4e-21 75.7 0.2 5.2e-21 75.1 0.2 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.4 001286933.1_41127001_3 - 7.6e-09 35.7 0.1 1.5e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.4 001286933.1_41127001_3 - 3.2e-08 33.4 3.7 0.0012 18.7 0.0 3.1 3 0 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_1 PF00560.31 001286933.1_41127001_3 - 1.8e-06 27.4 46.5 4 8.1 0.8 14.4 14 3 0 14 14 14 4 Leucine Rich Repeat LRR_9 PF14580.4 001286933.1_41127001_3 - 2.6e-05 23.7 13.8 0.023 14.1 0.2 4.7 2 2 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.4 001286933.1_41127001_3 - 0.00018 21.1 47.7 1.5 8.9 0.1 13.3 14 0 0 14 14 14 3 Leucine Rich repeat Cmc1 PF08583.8 001305641.1_21523001_3 - 2.8e-16 59.1 11.6 4.8e-16 58.4 11.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.11 001305641.1_21523001_3 - 0.0011 18.5 2.0 0.0011 18.5 2.0 2.7 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.9 001305641.1_21523001_3 - 0.044 14.1 7.1 0.095 13.0 7.1 1.5 1 0 0 1 1 1 0 GCK domain Cys_knot PF00007.20 001287605.1_01422001_1 - 1.6e-29 102.1 16.6 2.2e-29 101.7 16.6 1.2 1 0 0 1 1 1 1 Cystine-knot domain 7tm_1 PF00001.19 001134455.1_50022001_1 - 3.4e-31 108.3 36.7 2.2e-30 105.7 36.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001134455.1_50022001_1 - 2.4e-10 40.1 36.2 9.5e-10 38.1 36.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001134455.1_50022001_1 - 3.2e-10 40.1 24.7 4.5e-09 36.3 21.4 2.5 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001134455.1_50022001_1 - 1.9 7.6 38.1 1.1e+02 1.8 38.1 2.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx IFN-gamma PF00714.15 001286902.1_41122001_1 - 9.9e-28 96.6 2.6 1.4e-27 96.1 2.6 1.3 1 0 0 1 1 1 1 Interferon gamma Talin_middle PF09141.8 001286902.1_41122001_1 - 0.00093 19.1 0.5 0.0012 18.7 0.5 1.1 1 0 0 1 1 1 1 Talin, middle domain BNR_2 PF13088.4 001293132.1_02224001_1 - 4.7e-34 117.8 0.0 9.5e-29 100.4 0.0 2.1 2 0 0 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.4 001293132.1_02224001_1 - 1e-06 28.2 0.0 1.3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.18 001293132.1_02224001_1 - 0.00063 19.2 12.4 0.05 13.5 1.2 4.1 4 0 0 4 4 4 2 BNR/Asp-box repeat DNA_methylase PF00145.15 001293127.1_02226001_1 - 8.6e-17 61.3 0.1 1.1e-12 47.8 0.0 2.6 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase PWWP PF00855.15 001293127.1_02226001_1 - 4.1e-11 43.1 0.3 1.4e-10 41.4 0.3 1.9 1 0 0 1 1 1 1 PWWP domain E1-E2_ATPase PF00122.18 001245840.2_49923001_3 - 4e-27 94.8 0.0 7.1e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.24 001245840.2_49923001_3 - 1.2e-18 66.4 0.0 1.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_efflux PF01545.19 001245840.2_49923001_3 - 0.039 13.5 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family Oxidored_q3 PF00499.18 001245840.2_49923001_3 - 0.2 11.3 0.2 0.3 10.8 0.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 CHCH PF06747.11 001141580.2_46922001_1 - 0.009 16.0 0.9 0.12 12.4 0.7 2.5 1 1 1 2 2 2 2 CHCH domain p450 PF00067.20 138143.1_23524120_3 - 8e-16 57.7 0.4 1e-10 40.9 0.1 2.1 1 1 1 2 2 2 2 Cytochrome P450 DNA_methylase PF00145.15 001329369.1_27329001_1 - 1.3e-50 172.6 0.0 4.5e-50 170.7 0.0 2.0 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.6 001329369.1_27329001_1 - 3.6e-46 156.6 0.1 1.4e-45 154.7 0.0 2.1 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.16 001329369.1_27329001_1 - 5.1e-32 110.1 1.1 7e-16 58.0 0.1 2.9 3 0 0 3 3 3 2 BAH domain DMAP_binding PF06464.9 001329369.1_27329001_1 - 9.3e-18 64.9 4.8 9.3e-18 64.9 4.8 2.6 3 0 0 3 3 3 1 DMAP1-binding Domain zf-CXXC PF02008.18 001329369.1_27329001_1 - 3.4e-14 52.5 19.1 3.4e-14 52.5 19.1 2.6 2 0 0 2 2 2 1 CXXC zinc finger domain RST PF12174.6 001329369.1_27329001_1 - 0.018 14.8 0.3 0.098 12.5 0.6 2.0 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain GvpG PF05120.10 001329369.1_27329001_1 - 0.077 12.9 1.1 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Gas vesicle protein G BNR_2 PF13088.4 001293126.1_02224001_1 - 4.9e-35 121.0 0.0 6.6e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.18 001293126.1_02224001_1 - 1.9e-06 26.9 1.6 1.7 8.8 0.0 4.0 3 0 0 3 3 3 3 BNR/Asp-box repeat BNR_3 PF13859.4 001293126.1_02224001_1 - 1.1e-05 24.8 0.0 1.5e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain Insulin PF00049.16 001286846.1_01522001_3 - 1.6e-14 54.5 5.9 7.9e-12 45.9 5.9 2.5 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Basic PF01586.14 001282891.1_37522001_1 - 1.9e-29 102.5 0.5 1.3e-28 99.9 0.0 2.2 2 0 0 2 2 2 1 Myogenic Basic domain HLH PF00010.24 001282891.1_37522001_1 - 2.1e-13 49.9 5.1 3.7e-13 49.1 5.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HicB PF05534.10 001282891.1_37522001_3 - 0.035 13.8 0.3 0.065 13.0 0.3 1.5 1 0 0 1 1 1 0 HicB family Hormone_recep PF00104.28 001286292.1_25028001_1 - 2.9e-31 108.6 4.2 5.3e-31 107.7 4.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001286292.1_25028001_1 - 1.4e-24 86.1 12.6 4e-24 84.7 12.6 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GCR PF02155.13 001286292.1_25028001_1 - 1.6e-21 76.7 4.6 7e-21 74.5 4.6 1.8 1 1 0 1 1 1 1 Glucocorticoid receptor HSP70 PF00012.18 001286908.1_41125001_3 - 2.4e-264 878.0 12.5 2.7e-264 877.8 12.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001286908.1_41125001_3 - 2.2e-18 66.0 0.5 5.3e-17 61.5 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.4 001286908.1_41125001_3 - 0.002 18.4 4.3 1.4 9.2 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.14 001286908.1_41125001_3 - 0.0022 17.6 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.18 001286908.1_41125001_3 - 0.017 14.5 0.1 5.6 6.2 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.8 001286908.1_41125001_3 - 0.042 12.7 0.3 0.2 10.5 0.2 1.9 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Radial_spoke_3 PF06098.9 001286908.1_41125001_3 - 0.16 11.1 8.2 0.32 10.1 8.2 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 GLE1 PF07817.11 001286908.1_41125001_3 - 0.48 9.4 2.5 11 5.1 0.0 2.4 2 0 0 2 2 2 0 GLE1-like protein Basic PF01586.14 001286931.1_41122001_1 - 6.5e-24 84.8 0.2 1.9e-23 83.3 0.0 1.9 2 1 0 2 2 2 1 Myogenic Basic domain HLH PF00010.24 001286931.1_41122001_1 - 2.5e-13 49.6 5.6 4.5e-13 48.8 5.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myf5 PF12232.6 001286931.1_41122001_1 - 0.00016 22.2 2.7 0.0004 21.0 2.7 1.7 1 0 0 1 1 1 1 Myogenic determination factor 5 Arm PF00514.21 001286932.1_41126001_3 - 1.9e-42 141.9 19.2 1e-07 31.6 0.1 12.0 13 0 0 13 13 13 7 Armadillo/beta-catenin-like repeat Cnd1 PF12717.5 001286932.1_41126001_3 - 7.7e-09 35.6 2.4 0.0038 17.1 0.3 4.4 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.4 001286932.1_41126001_3 - 1.1e-06 28.8 6.6 1.3 9.5 0.0 6.3 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.20 001286932.1_41126001_3 - 2.4e-06 27.1 1.5 18 5.7 0.0 5.8 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.4 001286932.1_41126001_3 - 3.2e-06 27.3 6.4 0.034 14.4 0.3 5.0 4 1 1 5 5 5 1 HEAT repeats Adaptin_N PF01602.18 001286932.1_41126001_3 - 3.7e-06 25.7 2.7 0.00099 17.6 1.1 3.1 3 0 0 3 3 3 2 Adaptin N terminal region KAP PF05804.10 001286932.1_41126001_3 - 0.00022 19.4 1.4 0.038 12.0 0.0 3.3 1 1 1 3 3 3 1 Kinesin-associated protein (KAP) Atx10homo_assoc PF09759.7 001286932.1_41126001_3 - 0.00098 19.0 1.3 0.013 15.4 0.2 3.3 3 2 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.6 001286932.1_41126001_3 - 0.0013 18.6 2.4 2 8.2 0.0 4.5 2 1 1 4 4 4 1 Domain of unknown function (DUF3361) RasGEF_N_2 PF14663.4 001286932.1_41126001_3 - 0.0041 17.3 5.8 5.9 7.2 0.0 4.9 5 1 1 6 6 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Queuosine_synth PF02547.13 001286932.1_41126001_3 - 0.019 14.0 0.4 0.039 12.9 0.1 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein Arm_2 PF04826.11 001286932.1_41126001_3 - 0.024 14.0 3.9 0.77 9.0 0.0 3.5 2 1 1 3 3 3 0 Armadillo-like AAA PF00004.27 001293051.1_22323001_1 - 4.6e-43 146.7 0.0 1.2e-42 145.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293051.1_22323001_1 - 2.1e-07 31.1 0.0 5.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293051.1_22323001_1 - 2.7e-06 27.3 0.0 1.5e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293051.1_22323001_1 - 3.8e-06 27.3 0.2 7.4e-05 23.1 0.0 2.7 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293051.1_22323001_1 - 3.3e-05 24.1 1.0 0.0052 16.9 0.2 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293051.1_22323001_1 - 9e-05 21.7 0.0 0.00018 20.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293051.1_22323001_1 - 0.0015 17.4 0.0 0.0031 16.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293051.1_22323001_1 - 0.0018 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293051.1_22323001_1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293051.1_22323001_1 - 0.0025 18.2 0.2 0.02 15.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.9 001293051.1_22323001_1 - 0.0061 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.19 001293051.1_22323001_1 - 0.0063 15.8 0.1 0.016 14.5 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.11 001293051.1_22323001_1 - 0.0082 15.4 0.0 0.023 13.9 0.0 1.7 1 0 0 1 1 1 1 KaiC PhoH PF02562.14 001293051.1_22323001_1 - 0.0089 15.4 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.4 001293051.1_22323001_1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293051.1_22323001_1 - 0.019 15.0 3.4 0.051 13.7 3.4 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293051.1_22323001_1 - 0.022 14.3 0.1 0.099 12.2 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293051.1_22323001_1 - 0.026 14.1 0.0 0.074 12.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain TsaE PF02367.15 001293051.1_22323001_1 - 0.041 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293051.1_22323001_1 - 0.046 12.7 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.11 001293051.1_22323001_1 - 0.05 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.4 001293051.1_22323001_1 - 0.05 13.0 0.0 0.16 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.4 001293051.1_22323001_1 - 0.053 13.1 0.3 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.4 001293051.1_22323001_1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001293051.1_22323001_1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.4 001293051.1_22323001_1 - 0.074 13.3 0.6 0.47 10.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.10 001293051.1_22323001_1 - 0.12 11.5 0.2 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.4 001293051.1_22323001_1 - 0.13 12.5 0.2 0.51 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain SlyX PF04102.10 001293051.1_22323001_1 - 0.14 12.6 2.3 0.5 10.9 2.3 2.0 1 0 0 1 1 1 0 SlyX Laminin_II PF06009.10 001293051.1_22323001_1 - 0.18 11.7 3.6 1.2 9.0 1.0 2.7 3 0 0 3 3 3 0 Laminin Domain II DivIC PF04977.13 001293051.1_22323001_1 - 0.25 11.0 3.0 0.6 9.8 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator MscS_porin PF12795.5 001293051.1_22323001_1 - 6.8 6.0 12.7 11 5.3 12.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain 7tm_1 PF00001.19 001286737.1_27823001_1 - 1.4e-42 145.7 25.5 2.3e-42 145.0 25.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FixH PF05751.9 001286737.1_27823001_1 - 0.34 10.8 2.3 19 5.1 0.0 2.5 2 0 0 2 2 2 0 FixH Hormone_recep PF00104.28 001279723.1_37523001_1 - 5.2e-23 81.6 0.0 8.4e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor EF-hand_7 PF13499.4 001146542.1_46923001_1 - 2.3e-11 43.9 7.0 6.1e-10 39.3 2.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.30 001146542.1_46923001_1 - 2.5e-10 39.0 6.3 0.00072 18.8 0.1 4.1 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.4 001146542.1_46923001_1 - 1.1e-09 37.3 8.9 0.00063 19.4 0.6 4.6 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.4 001146542.1_46923001_1 - 4.7e-06 26.1 5.2 0.2 11.4 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.4 001146542.1_46923001_1 - 0.0029 16.9 7.7 0.46 10.0 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.5 001146542.1_46923001_1 - 0.1 12.4 3.5 1 9.2 0.1 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001146542.1_46923001_1 - 0.11 12.7 1.2 0.46 10.7 0.1 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Synaptobrevin PF00957.19 001141806.1_46924001_1 - 1.8e-33 114.1 3.8 3.2e-33 113.3 3.8 1.4 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.22 001245416.1_49922001_3 - 4.7e-42 143.8 0.0 5.9e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TerD PF02342.16 001245416.1_49922001_3 - 0.017 14.5 0.1 0.022 14.1 0.1 1.1 1 0 0 1 1 1 0 TerD domain Tubulin PF00091.23 001099690.2_49923001_2 - 8.3e-69 231.6 0.0 1.3e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001099690.2_49923001_2 - 8.7e-43 145.4 0.1 1.3e-42 144.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001099690.2_49923001_2 - 1.2e-05 25.4 0.0 3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001099690.2_49923001_2 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.4 001099690.2_49923001_2 - 0.016 14.3 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Patatin PF01734.20 001282838.1_13323001_2 - 1.4e-14 54.6 3.4 2.9e-13 50.3 3.4 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase LAT PF15234.4 003556.1_53421120_3 - 0.12 11.9 0.1 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells TMEM43 PF07787.10 001293002.1_08124001_2 - 3.2e-82 275.6 0.1 5.1e-82 274.9 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 43 Patatin PF01734.20 001311079.1_30924001_1 - 1.3e-14 54.7 3.6 2.1e-13 50.8 3.6 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4414 PF14377.4 001311079.1_30924001_1 - 0.14 12.3 0.8 0.22 11.7 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) SapB_1 PF05184.13 001311079.1_30924001_1 - 0.65 9.9 3.1 22 5.1 0.0 2.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 PurA PF04845.11 001315545.1_25022001_1 - 9.2e-101 335.6 0.0 1.1e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.6 001315545.1_25022001_1 - 0.049 13.6 6.5 2.7 8.0 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3276) PAS_11 PF14598.4 001329364.1_27324001_1 - 3.6e-26 91.4 0.5 4.6e-22 78.1 0.2 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 001329364.1_27324001_1 - 9.9e-21 73.7 0.0 2.6e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.10 001329364.1_27324001_1 - 3.3e-20 72.0 0.1 1.7e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.24 001329364.1_27324001_1 - 3.6e-17 61.9 1.0 6.8e-17 61.0 1.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001329364.1_27324001_1 - 9.3e-09 35.4 0.0 1.5e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001329364.1_27324001_1 - 0.00052 20.1 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.9 001329364.1_27324001_1 - 0.0076 16.8 0.0 0.067 13.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold Integrin_beta PF00362.16 001323203.1_13925001_1 - 2.5e-116 387.5 0.1 3.3e-116 387.1 0.1 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.9 001323203.1_13925001_1 - 4e-23 80.7 0.4 6.9e-23 79.9 0.4 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.10 001323203.1_13925001_1 - 4.3e-22 78.3 8.4 4.3e-22 78.3 8.4 4.3 6 0 0 6 6 6 1 Integrin beta tail domain PSI_integrin PF17205.1 001323203.1_13925001_1 - 3.1e-13 49.2 7.6 3.1e-13 49.2 7.6 5.0 5 2 0 5 5 5 1 Integrin plexin domain EGF_2 PF07974.11 001323203.1_13925001_1 - 2e-07 31.1 58.4 3.9e-05 23.8 15.2 6.7 6 1 1 7 7 7 3 EGF-like domain zf-AN1 PF01428.14 001256231.1_49927001_3 - 4.5e-08 33.0 7.9 2.3e-07 30.7 7.9 2.4 1 0 0 1 1 1 1 AN1-like Zinc finger zf-A20 PF01754.14 001256231.1_49927001_3 - 1.9e-05 24.3 6.5 8.5e-05 22.3 6.5 2.2 1 0 0 1 1 1 1 A20-like zinc finger Serpin PF00079.18 001329381.1_27323001_1 - 1.1e-94 317.7 1.0 1.3e-94 317.5 1.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4694 PF15765.3 001292873.1_08122001_2 - 0.063 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4694) Ribosomal_S30 PF04758.12 001292873.1_08122001_3 - 4.6e-30 103.5 12.1 6.4e-30 103.0 12.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.21 001292873.1_08122001_3 - 4.9e-12 45.3 0.0 6.8e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 001292873.1_08122001_3 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NAD_binding_4 PF07993.10 001302698.1_52324001_1 - 8.5e-78 260.9 0.0 1.1e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.17 001302698.1_52324001_1 - 5.2e-35 119.4 2.9 1.2e-34 118.3 2.9 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.19 001302698.1_52324001_1 - 4.2e-09 36.1 0.0 3e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001302698.1_52324001_1 - 1.1e-05 24.4 0.0 0.0049 15.8 0.1 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.13 001302698.1_52324001_1 - 4.6e-05 22.6 0.1 0.00011 21.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.3 001302698.1_52324001_1 - 7.4e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.22 001302698.1_52324001_1 - 0.00026 21.3 0.0 0.00049 20.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.8 001302698.1_52324001_1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.5 1 1 0 1 1 1 0 KR domain IRK PF01007.18 001323204.1_13923001_1 - 2.5e-157 522.9 1.9 3.1e-157 522.6 1.9 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK_N PF08466.8 001323204.1_13923001_1 - 1.6e-26 92.1 1.3 3.3e-26 91.0 1.3 1.6 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.14 001323204.1_13923001_1 - 0.00031 20.5 5.4 0.00069 19.4 5.4 1.7 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.29 001323204.1_13923001_1 - 0.003 16.7 5.4 0.0043 16.2 5.4 1.2 1 0 0 1 1 1 1 Ion transport protein SGT1 PF07093.9 001323487.1_23925001_1 - 5.9e-230 764.5 0.0 6.8e-230 764.3 0.0 1.0 1 0 0 1 1 1 1 SGT1 protein eIF3_subunit PF08597.8 001245471.1_49922001_2 - 5e-64 216.4 26.5 6.3e-64 216.0 26.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit GILT PF03227.14 001317044.1_41124001_1 - 5.6e-31 106.8 0.4 1e-30 105.9 0.4 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) SapA PF02199.13 001317044.1_41124001_1 - 0.027 14.5 2.9 0.072 13.1 2.9 1.7 1 0 0 1 1 1 0 Saposin A-type domain Reticulon PF02453.15 001292275.1_08123001_2 - 0.00021 21.1 6.2 0.00036 20.4 6.2 1.2 1 0 0 1 1 1 1 Reticulon DUF456 PF04306.11 001292275.1_08123001_2 - 0.69 10.1 6.9 0.15 12.2 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Rep_fac-A_C PF08646.8 001329378.1_27324001_1 - 2.9e-55 185.9 3.5 2.1e-52 176.6 2.3 2.6 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.3 001329378.1_27324001_1 - 1.2e-35 121.2 1.2 2.3e-34 117.1 0.5 2.3 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.10 001329378.1_27324001_1 - 9e-22 76.9 0.0 1.8e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.23 001329378.1_27324001_1 - 6.5e-13 48.4 0.9 1.4e-11 44.1 0.2 2.8 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Pox_vIL-18BP PF05566.10 001329378.1_27324001_1 - 0.046 13.8 0.7 0.64 10.1 0.2 2.8 2 1 1 3 3 3 0 Orthopoxvirus interleukin 18 binding protein zf-like PF04071.10 001329378.1_27324001_1 - 0.098 12.5 2.8 0.26 11.1 2.8 1.7 1 0 0 1 1 1 0 Cysteine-rich small domain zf-AN1 PF01428.14 001329378.1_27324001_1 - 0.98 9.5 3.8 2.2 8.4 3.8 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger IBR PF01485.19 001329378.1_27324001_1 - 7.7 6.7 11.2 0.71 10.0 5.8 2.0 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain adh_short PF00106.23 001292533.1_08123001_2 - 1.9e-26 92.6 1.1 1.1e-25 90.1 1.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001292533.1_08123001_2 - 5.2e-17 62.1 0.2 4.3e-16 59.1 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001292533.1_08123001_2 - 3.3e-07 30.3 0.2 5.8e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001292533.1_08123001_2 - 1.6e-05 24.3 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.8 001292533.1_08123001_2 - 0.0099 15.1 0.6 0.22 10.7 0.4 2.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.3 001292533.1_08123001_2 - 0.032 13.5 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 001292533.1_08123001_2 - 0.032 14.0 1.4 0.29 10.9 1.4 2.1 1 1 0 1 1 1 0 NAD(P)H-binding Pyr_redox_3 PF13738.4 001292533.1_08123001_2 - 0.033 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OprD PF03573.11 001292533.1_08123001_2 - 0.037 12.9 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 outer membrane porin, OprD family GDC-P PF02347.14 001310367.1_02128001_1 - 2.3e-204 679.0 0.0 1.7e-193 643.2 0.0 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.19 001310367.1_02128001_1 - 2.2e-09 36.9 0.0 5.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.17 001310367.1_02128001_1 - 3.4e-05 22.8 0.0 0.00019 20.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.19 001310367.1_02128001_1 - 0.016 14.3 0.0 0.046 12.8 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II Pyridoxal_deC PF00282.17 001310367.1_02128001_1 - 0.031 12.9 0.0 1.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain Collagen PF01391.16 001303357.1_27624001_1 - 1.6e-23 82.1 71.9 7.6e-09 35.1 25.2 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) HalX PF08663.8 001303357.1_27624001_1 - 0.022 14.9 0.9 5.9 7.1 0.1 3.5 3 0 0 3 3 3 0 HalX domain IncA PF04156.12 001303357.1_27624001_1 - 0.028 14.1 17.8 0.019 14.6 8.1 3.1 1 1 1 2 2 2 0 IncA protein PspA_IM30 PF04012.10 001303357.1_27624001_1 - 0.17 11.3 10.1 0.095 12.1 5.2 2.2 2 0 0 2 2 2 0 PspA/IM30 family DUF3450 PF11932.6 001303357.1_27624001_1 - 0.47 9.6 23.8 0.065 12.4 2.7 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.5 001303357.1_27624001_1 - 0.52 10.3 7.7 5.7 6.9 0.0 3.1 2 1 1 3 3 3 0 Tropomyosin like DUF4795 PF16043.3 001303357.1_27624001_1 - 0.58 9.6 18.1 72 2.7 15.7 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) COG5 PF10392.7 001303357.1_27624001_1 - 0.67 10.0 20.6 0.43 10.6 3.1 4.2 2 2 2 4 4 4 0 Golgi transport complex subunit 5 KxDL PF10241.7 001303357.1_27624001_1 - 1.1 9.4 17.7 2.8 8.1 0.6 4.1 2 1 1 3 3 3 0 Uncharacterized conserved protein TSNAXIP1_N PF15739.3 001303357.1_27624001_1 - 1.2 9.4 11.0 8.4 6.7 0.5 3.6 2 1 2 4 4 4 0 Translin-associated factor X-interacting N-terminus HIP1_clath_bdg PF16515.3 001303357.1_27624001_1 - 1.3 9.5 15.0 6.6 7.3 2.5 3.7 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mnd1 PF03962.13 001303357.1_27624001_1 - 1.6 8.4 12.1 0.82 9.4 3.1 2.6 1 1 2 3 3 3 0 Mnd1 family Laminin_II PF06009.10 001303357.1_27624001_1 - 1.9 8.3 20.3 1.3 8.9 1.8 4.4 2 1 2 4 4 4 0 Laminin Domain II FUSC PF04632.10 001303357.1_27624001_1 - 3 6.2 11.0 2.5 6.4 4.3 2.4 2 1 0 2 2 2 0 Fusaric acid resistance protein family BRE1 PF08647.9 001303357.1_27624001_1 - 3.3 7.7 18.1 0.11 12.4 1.8 3.5 4 1 0 4 4 3 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.10 001303357.1_27624001_1 - 5.5 6.9 20.4 12 5.8 0.6 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF1096 PF06493.9 001303357.1_27624001_3 - 5.1 7.5 9.7 19 5.7 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1096) Homeobox PF00046.27 001323492.1_23925001_1 - 1.3e-20 72.8 5.8 3.1e-20 71.6 5.8 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001323492.1_23925001_1 - 0.041 13.7 0.5 0.13 12.1 0.5 1.9 1 0 0 1 1 1 0 Homeobox KN domain EOS1 PF12326.6 001323492.1_23925001_1 - 1.6 8.5 5.9 0.096 12.5 0.3 1.8 2 0 0 2 2 2 0 N-glycosylation protein 7tm_1 PF00001.19 001323492.1_23925001_2 - 0.2 10.7 2.2 0.3 10.1 2.2 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Presenilin PF01080.15 001323492.1_23925001_2 - 5.3 5.6 9.6 0.086 11.4 2.9 1.4 2 0 0 2 2 2 0 Presenilin Ureide_permease PF07168.9 001323492.1_23925001_3 - 0.14 10.8 4.0 0.2 10.2 4.0 1.1 1 0 0 1 1 1 0 Ureide permease 7tm_1 PF00001.19 001323492.1_23925001_3 - 0.42 9.7 7.4 0.8 8.7 7.4 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Zip PF02535.20 001323492.1_23925001_3 - 0.6 9.1 5.3 0.95 8.5 5.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter EIIBC-GUT_N PF03612.12 001323492.1_23925001_3 - 0.97 9.0 13.4 1.7 8.2 13.4 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EOS1 PF12326.6 001323492.1_23925001_3 - 1.5 8.6 7.5 0.94 9.2 5.7 1.5 2 0 0 2 2 2 0 N-glycosylation protein Connexin PF00029.17 001323492.1_23925001_3 - 2 8.0 15.8 4.4 6.9 15.8 1.5 1 0 0 1 1 1 0 Connexin CLN3 PF02487.15 001323492.1_23925001_3 - 3.9 6.3 5.4 5.5 5.8 5.4 1.2 1 0 0 1 1 1 0 CLN3 protein 7tm_1 PF00001.19 001323794.1_35923001_2 - 2.3e-32 112.2 33.4 1.6e-31 109.4 33.4 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001323794.1_35923001_2 - 2.8e-11 43.5 12.2 2.8e-11 43.5 12.2 2.4 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.7 001323794.1_35923001_2 - 5.6e-09 35.6 31.2 2.7e-08 33.4 31.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001323794.1_35923001_2 - 1.4 8.0 34.6 0.0074 15.5 22.2 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx HlyIII PF03006.18 001323224.1_13923001_1 - 2.6e-46 158.0 16.6 4.1e-46 157.4 16.6 1.3 1 0 0 1 1 1 1 Haemolysin-III related IL6Ra-bind PF09240.8 001310388.1_02124001_3 - 2.6e-18 66.1 0.2 4e-18 65.5 0.2 1.3 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.8 001310388.1_02124001_3 - 1.1e-05 25.5 0.1 1.8e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.19 001310388.1_02124001_3 - 2.2e-05 24.6 0.5 4.6e-05 23.5 0.5 1.6 1 0 0 1 1 1 1 Fibronectin type III domain SRP14 PF02290.13 001292881.1_08122001_2 - 6.4e-26 90.4 0.0 1.1e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein zf-Tim10_DDP PF02953.13 001292165.1_08122001_1 - 2.3e-15 55.8 5.1 3.7e-15 55.2 5.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ion_trans PF00520.29 001315523.1_13324001_1 - 4.4e-50 170.1 9.2 5.9e-50 169.7 9.2 1.1 1 0 0 1 1 1 1 Ion transport protein K_channel_TID PF07941.9 001315523.1_13324001_1 - 5.6e-34 116.3 16.1 1.3e-33 115.2 16.1 1.6 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain BTB_2 PF02214.20 001315523.1_13324001_1 - 1.8e-27 95.3 0.0 4.3e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001315523.1_13324001_1 - 2.9e-13 49.5 4.9 2.9e-13 49.5 4.9 2.2 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.10 001315523.1_13324001_1 - 0.01 14.4 0.3 0.01 14.4 0.3 1.9 1 1 1 2 2 2 0 Polycystin cation channel Sigma_reg_N PF13800.4 001315523.1_13324001_1 - 0.068 13.3 2.7 7.6 6.8 0.0 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal IL6Ra-bind PF09240.8 001323202.1_13924001_1 - 1e-19 70.6 0.7 2.1e-19 69.6 0.7 1.6 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.8 001323202.1_13924001_1 - 3.4e-07 30.3 0.1 7e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.19 001323202.1_13924001_1 - 3.4e-06 27.2 3.1 5.6e-06 26.5 0.4 2.3 2 0 0 2 2 2 1 Fibronectin type III domain DCP1 PF06058.11 001323202.1_13924001_1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Dcp1-like decapping family Caveolin PF01146.15 001310814.1_02126001_1 - 5.3e-58 194.6 1.7 5.3e-58 194.6 1.7 1.9 2 0 0 2 2 2 1 Caveolin Adipogenin PF15202.4 001310814.1_02126001_3 - 1.8 8.5 9.1 3.2 7.7 2.9 2.4 2 0 0 2 2 2 0 Adipogenin SH3_9 PF14604.4 001318911.1_28124001_1 - 3.9e-10 39.3 0.0 7.3e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001318911.1_28124001_1 - 0.00038 19.9 0.0 0.00076 18.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain IncA PF04156.12 001318911.1_28124001_1 - 0.33 10.6 2.9 0.29 10.8 0.4 2.1 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.5 001318911.1_28124001_1 - 6.7 6.7 7.2 2.8 7.9 1.0 2.9 2 1 0 3 3 3 0 Tropomyosin like HMG_box PF00505.17 001323233.1_13924001_1 - 8.2e-26 90.1 1.3 2.5e-25 88.5 1.3 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.6 001323233.1_13924001_1 - 2e-25 89.5 0.3 2e-25 89.5 0.3 4.0 4 0 0 4 4 4 1 Sox developmental protein N terminal HMG_box_2 PF09011.8 001323233.1_13924001_1 - 1e-10 41.9 1.1 3e-10 40.4 1.1 1.9 1 0 0 1 1 1 1 HMG-box domain COQ7 PF03232.11 001311055.1_21522001_2 - 2.9e-73 245.1 0.0 3.5e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.15 001311055.1_21522001_2 - 0.0072 16.6 0.0 0.023 14.9 0.0 1.8 1 1 0 1 1 1 1 Rubrerythrin 7tm_1 PF00001.19 001303192.1_30824001_2 - 1.8e-44 151.9 25.5 2.8e-44 151.3 25.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.13 001303192.1_30824001_2 - 0.0027 17.6 4.7 0.0027 17.6 4.7 2.2 1 1 1 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa TFIID-18kDa PF02269.14 037143.1_49923120_3 - 3.2e-35 119.9 0.2 4.3e-35 119.5 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TP_methylase PF00590.18 001323486.1_23922001_3 - 8.9e-24 84.5 0.0 1.5e-23 83.7 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PBC PF03792.11 001323496.1_23925001_3 - 6.2e-92 306.4 0.3 1e-91 305.7 0.3 1.4 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.27 001323496.1_23925001_3 - 6.9e-18 64.1 0.5 1.4e-17 63.1 0.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001323496.1_23925001_3 - 6.9e-15 54.5 0.0 1.9e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.20 001323496.1_23925001_3 - 0.052 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix ANF_receptor PF01094.26 001315518.1_13327001_1 - 8.9e-59 199.2 0.1 1.5e-58 198.5 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001315518.1_13327001_1 - 1.8e-58 196.4 0.1 3.2e-58 195.7 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001315518.1_13327001_1 - 8e-46 154.8 0.1 1.5e-45 153.9 0.1 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001315518.1_13327001_1 - 2.2e-23 82.7 0.0 4.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.4 001315518.1_13327001_1 - 0.00029 20.5 0.0 0.0017 18.0 0.0 2.1 2 1 0 2 2 2 1 Periplasmic binding protein FtsJ PF01728.17 001311026.1_21522001_2 - 1.4e-51 175.0 0.0 1.7e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.4 001311026.1_21522001_2 - 0.013 15.2 0.0 0.42 10.2 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain AAA PF00004.27 001292411.1_08124001_2 - 9.5e-44 148.9 0.0 1.7e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 001292411.1_08124001_2 - 1.7e-06 28.4 0.2 0.00073 19.8 0.1 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.12 001292411.1_08124001_2 - 7.9e-06 25.8 0.2 0.0002 21.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.12 001292411.1_08124001_2 - 1.5e-05 25.1 0.0 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.4 001292411.1_08124001_2 - 1.9e-05 24.8 0.8 0.0035 17.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.10 001292411.1_08124001_2 - 3.6e-05 23.0 0.0 7.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Prot_ATP_ID_OB PF16450.3 001292411.1_08124001_2 - 0.00036 19.9 0.0 0.00085 18.7 0.0 1.5 2 0 0 2 2 1 1 Proteasomal ATPase OB/ID domain AAA_18 PF13238.4 001292411.1_08124001_2 - 0.00086 19.7 0.0 0.0035 17.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001292411.1_08124001_2 - 0.0022 18.1 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.11 001292411.1_08124001_2 - 0.0055 15.8 0.0 0.02 13.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.15 001292411.1_08124001_2 - 0.0093 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.15 001292411.1_08124001_2 - 0.01 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.9 001292411.1_08124001_2 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.4 001292411.1_08124001_2 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.11 001292411.1_08124001_2 - 0.015 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.20 001292411.1_08124001_2 - 0.016 15.5 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.19 001292411.1_08124001_2 - 0.018 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.15 001292411.1_08124001_2 - 0.019 14.5 0.2 2.8 7.4 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_24 PF13479.4 001292411.1_08124001_2 - 0.031 13.9 0.0 0.092 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.4 001292411.1_08124001_2 - 0.032 13.8 0.2 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain GAS PF13851.4 001292411.1_08124001_2 - 0.045 13.0 3.1 0.078 12.2 3.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding NACHT PF05729.10 001292411.1_08124001_2 - 0.084 12.6 0.0 0.26 11.1 0.0 1.8 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.11 001292411.1_08124001_2 - 0.092 11.9 0.1 0.76 8.9 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.4 001292411.1_08124001_2 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Bap31 PF05529.10 001292411.1_08124001_2 - 0.19 11.2 1.2 0.34 10.4 1.2 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like AAA_23 PF13476.4 001292411.1_08124001_2 - 0.83 10.0 4.2 51 4.2 4.9 2.3 2 0 0 2 2 2 0 AAA domain IncA PF04156.12 001292411.1_08124001_2 - 2.3 7.8 5.7 4.7 6.8 5.7 1.4 1 0 0 1 1 1 0 IncA protein Neur_chan_LBD PF02931.21 001323300.1_49624001_2 - 1.9e-73 246.3 1.1 2.5e-73 246.0 1.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001323300.1_49624001_2 - 1.8e-65 221.2 0.0 2.4e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Lipocalin PF00061.21 001303299.1_36022001_1 - 1.3e-24 86.9 2.8 1.6e-24 86.6 2.8 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001303299.1_36022001_1 - 4.7e-05 23.2 1.1 6.7e-05 22.7 1.1 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF3801 PF12687.5 001303299.1_36022001_1 - 0.045 13.7 0.1 0.053 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Cpn60_TCP1 PF00118.22 001303290.1_36024001_2 - 3.5e-154 514.0 5.8 4e-154 513.7 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.9 001303290.1_36024001_2 - 0.037 13.5 0.1 0.088 12.3 0.1 1.6 1 0 0 1 1 1 0 Propionate catabolism activator Fer4_15 PF13459.4 001303290.1_36024001_2 - 0.042 14.5 0.4 0.33 11.6 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain zf-C4 PF00105.16 001323221.1_13924001_2 - 1.5e-32 111.7 12.4 3.5e-32 110.6 12.4 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001323221.1_13924001_2 - 3.4e-25 88.7 8.5 7.2e-25 87.7 8.5 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-P11 PF03854.12 001323221.1_13924001_2 - 9.2 5.9 11.1 2.9 7.5 6.7 2.5 2 0 0 2 2 2 0 P-11 zinc finger UEV PF05743.11 001290672.1_11123001_2 - 1.3e-47 160.5 0.2 2.6e-47 159.5 0.2 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.8 001290672.1_11123001_2 - 3.9e-28 97.0 0.1 6.7e-28 96.3 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain DUF3450 PF11932.6 001290672.1_11123001_2 - 0.00041 19.6 7.3 0.0008 18.6 7.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) UQ_con PF00179.24 001290672.1_11123001_2 - 0.00043 19.8 0.3 0.00091 18.8 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APG6 PF04111.10 001290672.1_11123001_2 - 0.00093 18.5 4.7 0.0014 18.0 4.7 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 GPS2_interact PF15784.3 001290672.1_11123001_2 - 0.0077 16.8 6.5 0.023 15.2 6.5 1.8 1 1 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain Macoilin PF09726.7 001290672.1_11123001_2 - 0.0084 14.6 2.8 0.011 14.2 2.8 1.1 1 0 0 1 1 1 1 Transmembrane protein IncA PF04156.12 001290672.1_11123001_2 - 0.022 14.4 4.3 0.041 13.5 4.3 1.5 1 0 0 1 1 1 0 IncA protein DUF1640 PF07798.9 001290672.1_11123001_2 - 0.043 13.7 8.6 0.033 14.1 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ERM PF00769.17 001290672.1_11123001_2 - 0.044 13.5 12.6 0.083 12.6 12.6 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.13 001290672.1_11123001_2 - 0.058 12.8 1.5 0.079 12.4 1.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TBPIP PF07106.11 001290672.1_11123001_2 - 0.065 12.9 7.2 0.13 11.9 7.2 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fzo_mitofusin PF04799.11 001290672.1_11123001_2 - 0.097 12.1 4.3 0.21 10.9 4.3 1.5 1 0 0 1 1 1 0 fzo-like conserved region DUF342 PF03961.11 001290672.1_11123001_2 - 0.098 11.1 4.8 0.15 10.5 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Reo_sigmaC PF04582.10 001290672.1_11123001_2 - 0.11 11.7 0.3 0.18 11.1 0.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Prominin PF05478.9 001290672.1_11123001_2 - 0.17 9.6 1.3 0.24 9.2 1.3 1.1 1 0 0 1 1 1 0 Prominin Spc7 PF08317.9 001290672.1_11123001_2 - 0.25 10.0 10.8 0.41 9.4 10.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.10 001290672.1_11123001_2 - 0.31 10.9 4.4 0.73 9.7 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.10 001290672.1_11123001_2 - 0.35 11.4 11.6 0.29 11.6 2.4 3.3 2 1 1 3 3 3 0 SlyX Spc24 PF08286.9 001290672.1_11123001_2 - 0.53 10.4 12.1 0.89 9.7 4.6 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DASH_Spc19 PF08287.9 001290672.1_11123001_2 - 0.59 9.9 9.9 1.1 9.1 1.2 2.4 1 1 1 2 2 2 0 Spc19 TMPIT PF07851.11 001290672.1_11123001_2 - 0.62 9.1 3.7 0.96 8.5 3.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.9 001290672.1_11123001_2 - 0.73 10.1 10.5 1 9.6 0.8 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF724 PF05266.12 001290672.1_11123001_2 - 0.9 9.2 9.2 1.7 8.3 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1690 PF07956.9 001290672.1_11123001_2 - 1.4 9.2 8.2 2.4 8.5 8.2 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Spore_III_AB PF09548.8 001290672.1_11123001_2 - 1.6 8.7 5.2 2.5 8.0 5.2 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) V_ATPase_I PF01496.17 001290672.1_11123001_2 - 1.8 6.2 4.5 2.5 5.8 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.10 001290672.1_11123001_2 - 1.9 8.9 4.6 6.8 7.1 2.8 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Nsp1_C PF05064.11 001290672.1_11123001_2 - 3.3 7.4 9.0 1 9.1 4.4 2.4 2 1 1 3 3 3 0 Nsp1-like C-terminal region DUF4140 PF13600.4 001290672.1_11123001_2 - 4 7.8 7.8 42 4.5 7.2 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3782 PF12644.5 001290672.1_11123001_2 - 4.9 7.2 5.6 60 3.8 0.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3782) DivIC PF04977.13 001290672.1_11123001_2 - 5.9 6.6 12.4 1.7 8.3 2.0 2.6 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.7 001290672.1_11123001_2 - 7.2 5.5 7.3 13 4.6 7.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bap31 PF05529.10 001290672.1_11123001_2 - 8.4 5.8 8.0 15 5.0 8.0 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Snapin_Pallidin PF14712.4 001290672.1_11123001_2 - 9 6.7 12.5 0.93 9.8 1.8 2.8 2 1 1 3 3 3 0 Snapin/Pallidin Fib_alpha PF08702.8 001290672.1_11123001_2 - 10 6.2 8.8 2 8.5 5.2 1.7 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Neur_chan_LBD PF02931.21 001323085.1_07929001_1 - 9.9e-73 244.0 1.1 1.4e-72 243.5 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001323085.1_07929001_1 - 9.7e-65 218.8 0.0 1.3e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SNAP-25 PF00835.17 001323499.1_23925001_2 - 1.8e-20 72.9 0.2 3.3e-20 72.0 0.2 1.5 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.3 001323499.1_23925001_2 - 0.00039 20.2 5.8 0.0011 18.7 5.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) Sec20 PF03908.11 001323499.1_23925001_2 - 0.094 12.5 0.9 0.26 11.1 0.9 1.7 1 0 0 1 1 1 0 Sec20 Exonuc_VII_L PF02601.13 001323499.1_23925001_2 - 0.25 10.8 5.6 0.62 9.4 5.6 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit V-SNARE_C PF12352.6 001323499.1_23925001_2 - 0.55 10.4 5.8 0.36 11.0 0.8 2.7 2 2 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Spc7 PF08317.9 001323499.1_23925001_2 - 3.4 6.3 9.9 0.55 8.9 4.8 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.6 001323499.1_23925001_2 - 5.4 6.1 9.9 0.59 9.3 4.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Snapin_Pallidin PF14712.4 001323499.1_23925001_2 - 7.3 7.0 9.9 6.6 7.1 4.9 2.4 2 0 0 2 2 2 0 Snapin/Pallidin LIM PF00412.20 001292216.1_08124001_2 - 1.6e-40 137.0 30.0 5.2e-14 52.1 6.0 3.3 3 0 0 3 3 3 3 LIM domain PDZ PF00595.22 001292216.1_08124001_2 - 6.3e-16 58.4 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001292216.1_08124001_2 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Arm PF00514.21 001323485.1_23927001_1 - 2.7e-41 138.2 19.0 1.3e-07 31.3 0.1 11.8 13 0 0 13 13 13 7 Armadillo/beta-catenin-like repeat Cnd1 PF12717.5 001323485.1_23927001_1 - 1.4e-08 34.7 1.7 0.0055 16.6 0.3 4.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.4 001323485.1_23927001_1 - 5.6e-06 26.6 7.0 1.6 9.1 0.0 6.2 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.20 001323485.1_23927001_1 - 8.5e-06 25.5 1.5 24 5.4 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.4 001323485.1_23927001_1 - 9.1e-06 25.8 6.1 0.049 13.9 0.4 4.8 4 1 1 5 5 5 1 HEAT repeats Adaptin_N PF01602.18 001323485.1_23927001_1 - 1.4e-05 23.7 2.6 0.0025 16.3 0.9 3.1 3 0 0 3 3 3 2 Adaptin N terminal region Atx10homo_assoc PF09759.7 001323485.1_23927001_1 - 0.0016 18.3 0.9 0.016 15.1 0.2 3.0 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.6 001323485.1_23927001_1 - 0.0025 17.6 1.7 2.7 7.8 0.0 4.3 2 1 1 4 4 4 1 Domain of unknown function (DUF3361) RasGEF_N_2 PF14663.4 001323485.1_23927001_1 - 0.0029 17.8 3.7 7.7 6.8 0.0 4.6 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm_2 PF04826.11 001323485.1_23927001_1 - 0.025 13.9 3.2 0.93 8.8 0.1 3.3 2 1 1 3 3 3 0 Armadillo-like Queuosine_synth PF02547.13 001323485.1_23927001_1 - 0.032 13.2 0.4 0.061 12.3 0.1 1.5 2 0 0 2 2 2 0 Queuosine biosynthesis protein LSM PF01423.20 001292488.1_08122001_1 - 2.8e-14 52.4 0.2 4.4e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 LSM domain Neur_chan_LBD PF02931.21 001323081.1_13925001_3 - 5.1e-73 244.9 1.0 6.6e-73 244.6 1.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001323081.1_13925001_3 - 2e-65 221.0 0.0 2.6e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Orn_Arg_deC_N PF02784.14 001292635.1_08124001_1 - 1.4e-84 283.2 0.0 1.8e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001292635.1_08124001_1 - 1.6e-34 118.1 0.0 3.4e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Neur_chan_LBD PF02931.21 001323313.1_44624001_3 - 1.8e-73 246.4 1.1 2.5e-73 246.0 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001323313.1_44624001_3 - 2e-65 221.1 0.0 2.9e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region 2OG-FeII_Oxy_3 PF13640.4 001323785.1_15923001_2 - 3.4e-21 75.8 0.1 6.1e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.4 001323785.1_15923001_2 - 1.2e-09 38.6 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ion_trans PF00520.29 001302699.1_52324001_1 - 1.1e-44 152.4 12.8 1.4e-44 152.1 12.8 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001302699.1_52324001_1 - 8.1e-28 96.5 0.0 1.9e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001302699.1_52324001_1 - 4.8e-11 42.3 2.6 4.8e-11 42.3 2.6 2.4 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.3 001302699.1_52324001_1 - 0.0033 17.4 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Carn_acyltransf PF00755.18 001328250.1_15725001_1 - 1.9e-200 667.3 0.0 2.2e-200 667.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.3 001328250.1_15725001_1 - 9.2e-26 89.5 0.1 1.7e-25 88.6 0.1 1.5 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus HATPase_c_3 PF13589.4 001328250.1_15725001_1 - 0.051 13.3 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ras PF00071.20 001303210.1_30822001_1 - 1.2e-58 197.2 0.0 1.4e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001303210.1_30822001_1 - 1.6e-23 83.1 0.0 2.1e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001303210.1_30822001_1 - 3.5e-10 39.5 0.0 6.3e-10 38.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001303210.1_30822001_1 - 0.00024 20.5 0.0 0.00047 19.6 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001303210.1_30822001_1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001303210.1_30822001_1 - 0.038 13.2 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Enolase_C PF00113.20 001323488.1_23923001_1 - 3e-158 525.6 0.0 3.7e-158 525.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.14 001323488.1_23923001_1 - 2.3e-59 199.1 0.0 3.8e-59 198.4 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.4 001323488.1_23923001_1 - 7e-09 35.5 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.9 001323488.1_23923001_1 - 7.4e-05 21.9 0.3 7.4e-05 21.9 0.3 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Proteasome PF00227.24 001292230.1_08122001_1 - 8.5e-54 181.8 0.3 1.1e-53 181.4 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001292230.1_08122001_1 - 4.5e-15 54.9 0.1 9.4e-15 53.8 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DEAD PF00270.27 001329368.1_27325001_2 - 6e-48 162.8 0.0 1.4e-47 161.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001329368.1_27325001_2 - 6.1e-32 110.2 0.1 1.8e-31 108.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001329368.1_27325001_2 - 0.062 13.2 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PAS_11 PF14598.4 001323187.1_13928001_1 - 1.8e-20 73.0 2.1 9.7e-19 67.4 0.0 3.8 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.10 001323187.1_13928001_1 - 7.3e-16 58.1 1.1 3.2e-14 52.8 0.1 2.8 3 0 0 3 3 3 1 PAS fold PAS PF00989.23 001323187.1_13928001_1 - 3.2e-07 30.2 1.1 3e-06 27.1 0.0 3.1 3 0 0 3 3 3 1 PAS fold HLH PF00010.24 001323187.1_13928001_1 - 2.2e-06 27.4 0.4 5.4e-06 26.1 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001323187.1_13928001_1 - 0.0005 20.2 0.0 0.0017 18.4 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.4 001329366.1_27327001_3 - 3.1e-19 69.0 0.0 1.5e-16 60.4 0.0 3.1 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.10 001329366.1_27327001_3 - 2.7e-17 62.7 0.1 1.9e-13 50.4 0.1 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.23 001329366.1_27327001_3 - 2.1e-11 43.7 0.0 3.8e-08 33.2 0.0 3.1 2 0 0 2 2 2 2 PAS fold HLH PF00010.24 001329366.1_27327001_3 - 9.8e-06 25.3 0.3 2.5e-05 24.0 0.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001329366.1_27327001_3 - 0.00031 20.8 0.0 0.00094 19.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain RNA_pol_Rpb4 PF03874.14 001329366.1_27327001_3 - 0.056 13.6 11.2 1.4 9.2 0.3 2.8 2 1 0 2 2 2 0 RNA polymerase Rpb4 Tup_N PF08581.8 001329366.1_27327001_3 - 0.12 12.5 6.2 0.48 10.6 6.2 2.0 1 0 0 1 1 1 0 Tup N-terminal DUF2808 PF10989.6 001329366.1_27327001_3 - 0.41 10.5 6.8 0.08 12.8 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Patatin PF01734.20 001323228.1_13923001_2 - 1.1e-13 51.7 2.7 1.8e-12 47.7 2.7 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase IL15 PF02372.13 001033048.1_50022001_2 - 1.2e-08 34.9 1.0 2.2e-08 34.1 1.0 1.5 1 0 0 1 1 1 1 Interleukin 15 Yip1 PF04893.15 001200351.1_26623001_2 - 8.5e-19 67.8 13.6 1.2e-18 67.3 13.6 1.1 1 0 0 1 1 1 1 Yip1 domain DUF2070 PF09843.7 001200351.1_26623001_2 - 0.28 9.3 8.9 0.37 8.9 8.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CAF1 PF04857.18 001200811.1_26623001_3 - 3.7e-23 82.1 0.3 1.7e-11 43.8 0.0 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease Hormone_recep PF00104.28 001294191.1_15723001_2 - 1.1e-20 74.0 0.0 3.8e-20 72.2 0.0 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Band_7 PF01145.23 001303348.1_27624001_2 - 2.8e-21 76.2 0.1 2.8e-21 76.2 0.1 2.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.3 001303348.1_27624001_2 - 9.5e-09 35.4 3.7 9.5e-09 35.4 3.7 3.7 2 2 1 3 3 3 2 Flotillin 7tm_1 PF00001.19 001294190.1_15727001_2 - 9.4e-28 97.0 19.0 9.4e-28 97.0 19.0 2.2 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.4 001294190.1_15727001_2 - 4.7e-25 87.0 7.0 1.3e-08 34.3 0.1 4.3 3 1 1 4 4 4 3 Leucine rich repeat LRR_5 PF13306.4 001294190.1_15727001_2 - 5e-16 58.7 4.1 1.8e-09 37.5 2.6 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.5 001294190.1_15727001_2 - 2.2e-07 30.9 7.3 0.0096 16.2 0.1 5.6 2 2 4 6 6 6 4 Leucine Rich repeats (2 copies) Archease PF01951.14 001292171.1_08125001_2 - 2.7e-44 150.6 0.4 3.6e-44 150.2 0.4 1.2 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Ank_2 PF12796.5 001293113.1_02227001_1 - 3.1e-82 271.1 16.4 8.3e-13 48.6 0.1 7.9 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001293113.1_02227001_1 - 8.9e-65 214.2 21.5 9.5e-09 35.5 0.1 11.4 5 3 8 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.4 001293113.1_02227001_1 - 3e-61 196.0 14.8 9e-05 22.5 0.0 15.8 15 0 0 15 15 15 11 Ankyrin repeat Ank PF00023.28 001293113.1_02227001_1 - 5.5e-58 190.9 19.6 1.3e-06 28.5 0.0 15.4 15 0 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.4 001293113.1_02227001_1 - 3.2e-54 179.9 12.7 1.6e-07 31.4 0.0 11.7 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ion_trans PF00520.29 001293113.1_02227001_1 - 4.3e-14 52.2 22.9 7.6e-14 51.4 22.9 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.10 001293113.1_02227001_1 - 0.00028 19.5 22.6 0.00065 18.4 12.4 2.2 1 1 1 2 2 2 2 Polycystin cation channel DUF1843 PF08898.8 001293113.1_02227001_1 - 0.14 12.6 0.5 6.3 7.3 0.1 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) C1-set PF07654.13 001294240.1_15721001_1 - 7.4e-19 67.9 0.0 9.8e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_2 PF13895.4 001294240.1_15721001_1 - 0.00011 22.3 0.1 0.00033 20.8 0.0 1.7 1 1 1 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.4 001294240.1_15721001_1 - 0.0038 17.7 0.0 0.007 16.8 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Cna_B PF05738.11 001294240.1_15721001_1 - 0.053 14.0 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 Cna protein B-type domain ig PF00047.23 001294240.1_15721001_1 - 0.064 13.3 0.5 0.26 11.4 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.14 001294240.1_15721001_1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain 7tm_1 PF00001.19 001286288.1_25023001_2 - 1.1e-49 168.9 19.9 1.5e-49 168.5 19.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MHC_II_beta PF00969.17 001323214.1_13922001_1 - 3.2e-32 110.4 0.9 5.2e-32 109.7 0.9 1.4 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001323214.1_13922001_1 - 1.8e-24 85.9 0.0 2.6e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001323214.1_13922001_1 - 3.8e-05 24.1 0.0 6.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001323214.1_13922001_1 - 0.00035 20.6 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001323214.1_13922001_1 - 0.00056 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.4 001323214.1_13922001_1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.10 001323214.1_13922001_1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain MHC_I PF00129.16 001323214.1_13922001_1 - 0.076 12.4 0.4 0.22 10.9 0.5 1.5 1 1 1 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 IncA PF04156.12 001323214.1_13922001_1 - 0.19 11.4 0.1 21 4.7 0.0 2.1 2 0 0 2 2 2 0 IncA protein Phage_holin_3_6 PF07332.9 001323214.1_13922001_1 - 8.1 6.4 7.2 3.8 7.4 2.5 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DEAD PF00270.27 001294221.1_15725001_3 - 9e-50 168.7 0.0 1.5e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001294221.1_15725001_3 - 1e-29 103.0 0.0 7.2e-29 100.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001294221.1_15725001_3 - 0.027 14.3 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Glyco_transf_29 PF00777.16 001280068.1_50023001_1 - 2.8e-68 230.1 0.0 3.3e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF3346 PF11826.6 001280068.1_50023001_1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) A2M_N PF01835.17 033392.1_53529120_1 - 2.6e-06 27.7 0.0 4.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 MG2 domain A2M_comp PF07678.12 033392.1_53529120_2 - 1.8e-40 138.9 1.2 1.9e-39 135.5 1.2 2.1 1 1 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.20 033392.1_53529120_2 - 2.5e-28 97.6 0.1 4.7e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.12 033392.1_53529120_2 - 3.3e-23 82.4 0.0 8.3e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin family N-terminal region Thiol-ester_cl PF10569.7 033392.1_53529120_2 - 5.4e-08 32.3 0.2 1.1e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Cas_Cas2CT1978 PF09707.8 033392.1_53529120_2 - 0.13 12.3 0.0 29 4.7 0.0 2.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) A2M_recep PF07677.12 033392.1_53529120_3 - 1.4e-25 89.7 0.1 3.2e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 A-macroglobulin receptor NTR PF01759.19 033392.1_53529120_3 - 2.1e-24 85.3 0.9 7.2e-24 83.5 0.1 2.0 2 0 0 2 2 2 1 UNC-6/NTR/C345C module DUF1451 PF07295.9 036688.1_53525120_1 - 0.18 11.7 2.3 0.28 11.1 2.3 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain MARVEL PF01284.21 036688.1_53525120_2 - 6.1e-13 48.9 10.3 1.6e-12 47.5 10.3 1.6 1 0 0 1 1 1 1 Membrane-associating domain NfeD PF01957.16 036688.1_53525120_2 - 1.6 9.0 5.7 3.1 8.1 5.7 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding GARS_A PF01071.17 131617.1_16128001_3 - 4.5e-89 297.3 0.0 6.9e-89 296.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.17 131617.1_16128001_3 - 7.9e-63 211.3 0.0 1.3e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.13 131617.1_16128001_3 - 1.8e-34 118.2 0.6 1.2e-32 112.4 0.1 2.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.20 131617.1_16128001_3 - 1.1e-32 113.1 0.0 1.3e-31 109.7 0.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.14 131617.1_16128001_3 - 1.9e-28 98.4 0.8 1.1e-27 96.0 0.4 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.22 131617.1_16128001_3 - 3.5e-15 56.3 1.3 1.5e-14 54.3 1.3 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.4 131617.1_16128001_3 - 6.9e-07 28.1 0.0 1.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.15 131617.1_16128001_3 - 0.0011 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.20 131617.1_16128001_3 - 0.0017 17.8 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.12 131617.1_16128001_3 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.4 131617.1_16128001_3 - 0.045 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.9 131617.1_16128001_3 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain CARD_2 PF16739.3 001311190.1_02526001_1 - 9.8e-41 137.5 7.1 6.4e-21 74.0 0.3 3.5 4 0 0 4 4 4 2 Caspase recruitment domain RIG-I_C-RD PF11648.6 001311190.1_02526001_1 - 1.5e-36 125.1 4.0 5.3e-36 123.3 4.0 2.1 1 0 0 1 1 1 1 C-terminal domain of RIG-I ResIII PF04851.13 001311190.1_02526001_1 - 2.6e-18 66.5 2.7 4.4e-17 62.5 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.27 001311190.1_02526001_1 - 2e-17 63.4 0.0 6e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001311190.1_02526001_1 - 1.3e-14 54.3 0.0 4.7e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_25 PF13481.4 001311190.1_02526001_1 - 0.0068 15.9 0.0 0.02 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.4 001311190.1_02526001_1 - 0.14 12.3 0.2 0.84 9.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.4 001311190.1_02526001_1 - 0.16 12.2 1.0 0.77 10.0 0.0 2.6 3 1 0 3 3 3 0 AAA domain Cytochrome_C554 PF13435.4 001311190.1_02526001_1 - 0.35 11.7 3.1 1.4 9.7 1.9 2.7 2 0 0 2 2 2 0 Cytochrome c554 and c-prime UvrD-helicase PF00580.19 001311190.1_02526001_1 - 0.98 8.7 6.6 6.3 6.1 0.0 3.1 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF846 PF05832.10 001281928.1_30922001_1 - 1.7e-54 183.5 10.0 2e-54 183.2 10.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF846 PF05832.10 001281869.1_30823001_2 - 2.6e-54 182.9 8.1 3.5e-54 182.5 8.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) EBA-175_VI PF11556.6 001281963.1_22524001_1 - 0.18 12.0 1.1 0.44 10.8 0.1 2.1 2 0 0 2 2 2 0 Erythrocyte binding antigen 175 DUF846 PF05832.10 001281963.1_22524001_3 - 1.4e-53 180.6 8.8 2e-53 180.0 8.8 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) p450 PF00067.20 001302363.1_41624001_1 - 1e-108 363.9 0.0 1.3e-108 363.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001302368.1_41626001_2 - 2.3e-106 356.2 0.0 3e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 T4_deiodinase PF00837.15 001136144.1_50022001_1 - 1.8e-68 230.2 0.0 2.2e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase CHORD PF04968.10 001006700.1_53524001_2 - 4.5e-52 174.5 17.1 2.3e-28 98.6 1.7 3.2 3 0 0 3 3 3 2 CHORD CS PF04969.14 001006700.1_53524001_3 - 0.0002 22.2 0.1 0.00077 20.3 0.0 1.9 2 0 0 2 2 2 1 CS domain Daxx PF03344.13 001092990.1_53427001_3 - 1.7e-40 136.9 1.1 1.7e-40 136.9 1.1 2.4 2 0 0 2 2 2 1 Daxx N-terminal Rassf1C-interacting domain Ribosomal_L7Ae PF01248.24 001016151.3_53523001_2 - 7.3e-13 47.9 0.1 1.4e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L15e PF00827.15 001011478.1_53522001_2 - 1.1e-93 312.1 4.6 1.4e-93 311.8 4.6 1.1 1 0 0 1 1 1 1 Ribosomal L15 DUF106 PF01956.14 001016907.1_53525001_3 - 1.6e-50 171.0 3.5 1.6e-50 171.0 3.5 2.1 2 0 0 2 2 2 1 Integral membrane protein DUF106 G-alpha PF00503.18 001090213.1_53427001_1 - 1.9e-105 352.8 5.5 1.9e-105 352.8 5.5 1.5 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.19 001090213.1_53427001_1 - 2.3e-15 56.3 3.1 6.8e-13 48.3 0.5 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.11 001090213.1_53427001_1 - 0.00038 20.5 1.6 0.16 12.1 0.2 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.10 001090213.1_53427001_1 - 0.0053 16.0 0.2 0.0053 16.0 0.2 2.7 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region TniB PF05621.9 001090213.1_53427001_1 - 0.019 14.0 0.3 0.033 13.3 0.3 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF4604 PF15377.4 001090213.1_53427001_2 - 0.21 11.9 20.2 0.096 13.0 13.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Ribosomal_L37ae PF01780.17 001005137.1_53521001_2 - 1.2e-46 156.6 10.8 1.4e-46 156.3 10.8 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rsm1 PF08600.8 001005137.1_53521001_2 - 0.022 14.8 0.6 0.031 14.3 0.6 1.2 1 0 0 1 1 1 0 Rsm1-like zf-C4_ClpX PF06689.11 001005137.1_53521001_2 - 0.24 11.2 4.2 0.69 9.7 4.2 1.8 1 1 0 1 1 1 0 ClpX C4-type zinc finger PX PF00787.22 001091476.1_53424001_2 - 4e-25 87.9 2.5 4.1e-25 87.8 1.0 1.7 2 0 0 2 2 2 1 PX domain Vps5 PF09325.8 001091476.1_53424001_2 - 2.9e-06 26.9 6.5 1e-05 25.1 2.8 2.4 2 1 0 2 2 2 1 Vps5 C terminal like DUF16 PF01519.14 001091476.1_53424001_2 - 0.0021 18.4 2.1 0.49 10.8 0.3 3.7 3 1 0 3 3 3 1 Protein of unknown function DUF16 DUF713 PF05218.12 001091476.1_53424001_2 - 0.0034 17.0 4.0 0.0046 16.6 1.7 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF713) BAR PF03114.16 001091476.1_53424001_2 - 0.0078 15.7 2.8 0.023 14.2 2.8 1.7 1 1 0 1 1 1 1 BAR domain Kinetocho_Slk19 PF12709.5 001091476.1_53424001_2 - 0.05 13.9 1.3 0.13 12.5 1.3 1.7 1 0 0 1 1 1 0 Central kinetochore-associated ZapB PF06005.10 001091476.1_53424001_2 - 0.23 11.8 1.5 0.62 10.4 1.5 1.7 1 0 0 1 1 1 0 Cell division protein ZapB Tetraspannin PF00335.18 001091476.1_53424001_2 - 0.61 9.7 2.2 2.3 7.9 2.4 1.8 1 1 0 1 1 1 0 Tetraspanin family TPR_2 PF07719.15 001006868.1_53526001_3 - 7e-18 63.1 0.4 2.1e-05 24.1 0.0 5.3 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.26 001006868.1_53526001_3 - 2.2e-15 55.6 0.4 0.00061 19.4 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.4 001006868.1_53526001_3 - 3.7e-12 46.2 1.6 0.00034 20.7 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.4 001006868.1_53526001_3 - 1.4e-10 41.4 0.2 3.2e-07 30.7 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.4 001006868.1_53526001_3 - 5.7e-09 36.4 0.0 0.0056 17.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.4 001006868.1_53526001_3 - 2.4e-08 33.4 0.3 0.42 10.8 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.4 001006868.1_53526001_3 - 3.1e-07 30.5 0.0 0.00078 19.8 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.4 001006868.1_53526001_3 - 4.4e-06 26.9 0.0 0.41 11.5 0.0 4.5 4 1 2 6 6 3 1 Tetratricopeptide repeat TPR_17 PF13431.4 001006868.1_53526001_3 - 1.1e-05 25.3 1.4 0.16 12.3 0.1 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat Coatomer_E PF04733.12 001006868.1_53526001_3 - 7.7e-05 22.1 0.2 0.00014 21.3 0.2 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.5 001006868.1_53526001_3 - 0.00024 21.1 0.3 0.0089 16.1 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.4 001006868.1_53526001_3 - 0.11 12.5 0.0 8.7 6.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.4 001006868.1_53526001_3 - 0.16 11.6 0.2 3.7 7.2 0.1 2.8 2 1 0 2 2 2 0 TPR repeat Ribosomal_S2 PF00318.18 001091834.1_53423001_1 - 1.7e-42 145.0 0.4 2.9e-21 75.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 DAGK_cat PF00781.22 001092758.1_53425001_2 - 1.6e-26 92.3 0.0 2.4e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SRP_TPR_like PF17004.3 001092495.1_53425001_1 - 3.9e-21 75.1 1.7 3.9e-21 75.1 1.7 3.1 3 1 0 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.10 001092495.1_53425001_1 - 1e-18 67.3 8.3 1e-18 67.3 8.3 2.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.4 001092495.1_53425001_1 - 3e-16 59.6 9.1 5.7e-05 23.4 0.1 6.5 6 2 1 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.5 001092495.1_53425001_1 - 2e-14 53.4 12.1 0.00018 21.5 0.3 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.4 001092495.1_53425001_1 - 2.2e-14 52.7 0.3 0.2 12.5 0.6 8.1 4 2 4 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.15 001092495.1_53425001_1 - 1e-10 40.8 7.6 0.02 14.8 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.4 001092495.1_53425001_1 - 7.1e-10 38.7 10.0 0.0061 17.0 0.1 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.4 001092495.1_53425001_1 - 7.3e-08 32.5 10.0 0.56 10.4 0.1 7.1 5 3 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.4 001092495.1_53425001_1 - 5.6e-07 30.0 0.0 3.3 8.3 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.15 001092495.1_53425001_1 - 2.5e-06 27.9 4.7 0.074 13.3 0.1 4.2 4 2 0 4 4 4 2 Bacterial transcriptional activator domain TPR_1 PF00515.26 001092495.1_53425001_1 - 3.5e-06 26.5 4.4 0.034 13.8 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.4 001092495.1_53425001_1 - 0.00014 21.8 0.1 3.5 7.7 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.4 001092495.1_53425001_1 - 0.00018 21.0 0.7 0.57 9.8 0.0 5.1 5 0 0 5 5 5 1 TPR repeat TPR_8 PF13181.4 001092495.1_53425001_1 - 0.00035 20.4 7.0 3.2 8.1 0.0 7.1 9 1 0 9 9 7 1 Tetratricopeptide repeat TPR_21 PF09976.7 001092495.1_53425001_1 - 0.00073 19.2 3.4 0.00073 19.2 3.4 4.3 3 2 2 5 5 5 1 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.8 001092495.1_53425001_1 - 0.0013 18.2 1.7 0.053 13.0 0.3 3.7 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) DUF627 PF04781.10 001092495.1_53425001_1 - 0.0026 17.6 4.5 1 9.3 0.4 5.0 4 1 1 5 5 5 1 Protein of unknown function (DUF627) TPR_3 PF07720.10 001092495.1_53425001_1 - 0.053 13.4 2.9 16 5.5 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.4 001092495.1_53425001_1 - 0.072 13.4 2.6 3.8 7.8 0.9 3.5 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TraS PF10624.7 001092495.1_53425001_1 - 0.1 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS HemY_N PF07219.11 001092495.1_53425001_1 - 0.3 11.1 4.9 2.1 8.4 0.0 4.2 5 0 0 5 5 4 0 HemY protein N-terminus EAP30 PF04157.14 001092495.1_53425001_1 - 0.4 9.8 10.4 1.5 7.9 1.4 3.7 1 1 2 4 4 4 0 EAP30/Vps36 family TPR_20 PF14561.4 001092495.1_53425001_1 - 0.41 10.9 10.7 1.5 9.1 0.8 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF4919 PF16266.3 001092495.1_53425001_1 - 2.4 7.9 7.3 1.3 8.8 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4919) CCDC-167 PF15188.4 001092495.1_53425001_1 - 3.4 7.9 5.8 1.8 8.8 0.2 3.0 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 MA3 PF02847.15 001086428.1_53423001_3 - 1.6e-40 137.5 0.0 3.4e-20 72.0 0.1 2.2 2 0 0 2 2 2 2 MA3 domain PPR PF01535.18 001086428.1_53423001_3 - 0.12 12.5 1.2 41 4.6 0.1 3.4 3 0 0 3 3 3 0 PPR repeat Sin_N PF04801.11 001091761.1_53426001_3 - 1.4e-156 521.9 7.4 1.4e-156 521.9 7.4 2.6 2 1 0 2 2 2 2 Sin-like protein conserved region PA26 PF04636.11 001092009.1_53425001_1 - 1.4e-203 676.6 5.1 1.6e-203 676.4 5.1 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.18 001092009.1_53425001_1 - 2.8e-05 23.9 0.0 8.1e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF342 PF03961.11 001092009.1_53425001_1 - 0.014 13.9 0.8 0.019 13.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cwf_Cwc_15 PF04889.10 001092009.1_53425001_1 - 0.015 14.9 5.4 0.022 14.3 5.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_S6 PF01250.15 001097389.1_53522001_1 - 3.5e-18 65.5 0.0 4.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Bcl-2 PF00452.17 001011065.1_53524001_3 - 3e-30 104.6 0.1 5.7e-30 103.7 0.1 1.5 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.15 001011065.1_53524001_3 - 3.8e-10 39.2 0.0 7.2e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Bcl-2 homology region 4 DUF1360 PF07098.9 001097941.1_53421001_1 - 0.05 13.4 1.7 0.088 12.6 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) NDUF_C2 PF06374.9 001097941.1_53421001_2 - 4.3e-39 133.0 0.0 5.3e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Shal-type PF11601.6 001093997.1_53427001_1 - 0.25 10.8 1.2 0.45 10.0 1.2 1.4 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal DUF4628 PF15429.4 001093997.1_53427001_3 - 1.4e-89 300.3 7.4 1.4e-89 300.3 7.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4628) PID PF00640.21 001093997.1_53427001_3 - 2e-29 102.3 1.8 5.1e-29 101.0 1.8 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) CoA_binding_3 PF13727.4 001093997.1_53427001_3 - 0.044 13.7 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 CoA-binding domain DivIC PF04977.13 001093997.1_53427001_3 - 2 8.1 9.7 1.4 8.6 7.5 1.8 1 1 0 1 1 1 0 Septum formation initiator Cadherin PF00028.15 001093921.1_53427001_2 - 9.6e-17 61.1 9.1 6.5e-07 29.6 0.2 4.4 4 0 0 4 4 4 3 Cadherin domain Met_10 PF02475.14 001096340.1_53424001_2 - 2.2e-41 141.6 0.0 3.7e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Met_10 PF02475.14 001096340.1_53424001_3 - 1.7e-17 63.7 0.0 2.5e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.14 001096340.1_53424001_3 - 0.012 14.7 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MENTAL PF10457.7 001130258.1_53526001_2 - 3.3e-60 202.8 5.7 5.6e-60 202.1 5.7 1.4 1 0 0 1 1 1 1 Cholesterol-capturing domain CAP PF00188.24 001114032.1_53525001_3 - 4.1e-49 166.5 9.0 9.9e-21 74.8 0.4 3.2 3 0 0 3 3 3 3 Cysteine-rich secretory protein family RRM_1 PF00076.20 001093280.1_53423001_2 - 4.8e-16 58.2 0.0 7e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.21 001093280.1_53423001_2 - 7.6e-05 22.5 5.5 0.00021 21.1 5.5 1.8 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.4 001093280.1_53423001_2 - 0.00032 20.1 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.4 001093280.1_53423001_2 - 0.0015 18.4 3.8 0.0041 16.9 3.8 1.8 1 0 0 1 1 1 1 Zinc knuckle DEAD PF00270.27 001142076.1_53527001_3 - 3e-18 66.1 0.0 4.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001142076.1_53527001_3 - 1.6e-15 57.3 0.0 5.9e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.3 001142076.1_53527001_3 - 1.2e-11 44.9 1.9 3.9e-11 43.3 1.7 2.1 2 0 0 2 2 2 1 RecQ zinc-binding RecQ5 PF06959.9 001142076.1_53527001_3 - 8.1e-08 32.3 7.4 8.1e-08 32.3 7.4 3.7 3 1 1 4 4 4 2 RecQ helicase protein-like 5 (RecQ5) ResIII PF04851.13 001142076.1_53527001_3 - 0.00028 20.8 0.0 0.00069 19.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KIX_2 PF16987.3 001142076.1_53527001_3 - 0.0016 18.2 0.1 0.0057 16.5 0.1 2.0 1 0 0 1 1 1 1 KIX domain SRI PF08236.9 001142076.1_53527001_3 - 0.01 15.8 0.9 0.035 14.1 0.9 1.9 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain PAG PF15347.4 001093210.1_53425001_2 - 5.6e-177 588.9 16.2 6.7e-177 588.7 16.2 1.0 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched Cadherin_C_2 PF16492.3 001093210.1_53425001_2 - 0.04 14.6 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Comm PF15957.3 001093210.1_53425001_2 - 0.077 13.2 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Commissureless EF-hand_1 PF00036.30 001114265.1_53524001_2 - 4.5e-28 94.5 17.2 4.3e-09 35.1 0.4 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.4 001114265.1_53524001_2 - 2.5e-24 82.9 5.9 1.1e-08 34.2 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.4 001114265.1_53524001_2 - 2.9e-24 85.2 7.9 3e-14 53.1 1.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001114265.1_53524001_2 - 2.3e-20 72.0 12.3 2.5e-12 46.2 0.9 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.4 001114265.1_53524001_2 - 5.1e-19 66.7 11.7 4.2e-08 32.2 0.2 3.7 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.4 001114265.1_53524001_2 - 3.5e-10 39.9 0.5 0.00048 20.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.7 001114265.1_53524001_2 - 0.00056 20.1 0.1 0.041 14.1 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DIMCO_N PF16844.3 001114265.1_53524001_2 - 0.052 13.7 0.1 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal TerB PF05099.11 001114265.1_53524001_2 - 0.082 12.7 0.1 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB EF-hand_4 PF12763.5 001114265.1_53524001_2 - 0.15 11.9 2.0 0.35 10.7 0.2 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.16 001114265.1_53524001_2 - 0.86 9.5 3.9 23 5.0 0.1 2.6 2 0 0 2 2 2 0 Dockerin type I repeat G-gamma PF00631.20 001171620.1_53522001_1 - 8.3e-16 57.6 0.0 1.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 GGL domain EphA2_TM PF14575.4 001171620.1_53522001_1 - 0.57 10.9 0.0 0.57 10.9 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Kinesin PF00225.21 001128654.1_53529001_3 - 1.6e-109 365.7 0.8 1.6e-109 365.7 0.8 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.3 001128654.1_53529001_3 - 1.1e-27 96.7 0.1 1.1e-27 96.7 0.1 2.5 3 0 0 3 3 3 1 Microtubule binding Reo_sigmaC PF04582.10 001128654.1_53529001_3 - 0.12 11.7 24.8 0.5 9.6 3.8 3.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein RELT PF12606.6 045263.1_53524120_1 - 4.9e-22 76.9 0.4 1.2e-21 75.7 0.4 1.7 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 ARPC4 PF05856.10 001303878.1_21522001_1 - 2.2e-61 206.2 1.8 2.9e-61 205.8 1.8 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.3 001303878.1_21522001_1 - 0.0011 18.9 0.1 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 Sm_like domain ARPC4 PF05856.10 001303878.1_21522001_2 - 5.4e-17 61.8 0.3 7.6e-17 61.3 0.3 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Rft-1 PF04506.11 001142872.1_23526001_1 - 9e-141 470.0 21.7 1.1e-140 469.7 21.7 1.1 1 0 0 1 1 1 1 Rft protein Leptin PF02024.13 001311350.1_22322001_1 - 2.5e-26 92.1 0.0 3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Leptin GSHPx PF00255.17 138101.1_53523120_3 - 2.4e-30 104.1 0.3 1.8e-19 69.2 0.0 2.3 2 0 0 2 2 2 2 Glutathione peroxidase GSHPx PF00255.17 138100.1_53523120_2 - 2.2e-08 33.5 0.0 3.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.17 138100.1_53523120_3 - 6e-20 70.7 0.0 9.8e-20 70.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase Pro_isomerase PF00160.19 046434.1_53524120_3 - 4.4e-37 127.7 0.4 6e-37 127.2 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bcl-2 PF00452.17 001257283.2_23526001_1 - 3.1e-24 85.3 0.3 4.9e-24 84.7 0.3 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BALF1 PF06861.9 001257283.2_23526001_1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 BALF1 protein Exo_endo_phos PF03372.21 001184759.1_23524001_2 - 7.5e-12 45.4 0.0 1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.4 001184759.1_23524001_2 - 0.0004 20.1 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Ctr PF04145.13 001305656.1_23529001_2 - 3.4e-32 112.0 4.1 6.3e-32 111.1 4.1 1.5 1 0 0 1 1 1 1 Ctr copper transporter family A_deamin PF02137.16 004440.1_23529120_2 - 7.5e-117 390.3 0.0 9.5e-117 389.9 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.24 004440.1_23529120_2 - 2.7e-26 91.9 0.2 5.6e-13 49.2 0.1 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif E1-E2_ATPase PF00122.18 073529.2_23529120_3 - 6.3e-64 215.2 1.3 6.3e-64 215.2 1.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.19 073529.2_23529120_3 - 1.3e-45 155.2 2.4 3.7e-45 153.7 2.4 1.9 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.4 073529.2_23529120_3 - 9e-21 73.6 0.3 1.6e-20 72.8 0.3 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.24 073529.2_23529120_3 - 2e-17 64.1 0.0 3.7e-16 59.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 073529.2_23529120_3 - 1e-16 60.2 1.2 3e-16 58.7 0.2 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.10 073529.2_23529120_3 - 1.6e-05 24.6 0.6 3.3e-05 23.6 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.5 073529.2_23529120_3 - 0.0067 16.7 0.1 0.021 15.1 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Nramp PF01566.16 001128101.1_23524001_3 - 1.1e-118 396.1 12.8 1.8e-118 395.5 12.8 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein MRG PF05712.11 001037176.1_23524001_3 - 1.1e-54 184.6 0.6 1.9e-54 183.9 0.6 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.6 001037176.1_23524001_3 - 8.6e-16 57.5 0.4 1.8e-15 56.4 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Fmp27_WPPW PF10359.7 001037176.1_23524001_3 - 0.047 12.4 0.7 0.063 12.0 0.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain EF-hand_7 PF13499.4 102414.1_23523120_1 - 5.9e-11 42.6 4.2 5.5e-10 39.5 0.9 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.4 102414.1_23523120_1 - 7.7e-10 37.8 5.2 0.00019 21.0 0.6 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.30 102414.1_23523120_1 - 1.4e-09 36.7 8.1 0.0002 20.5 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.4 102414.1_23523120_1 - 8e-06 25.4 6.3 0.016 14.8 2.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 102414.1_23523120_1 - 0.00043 19.6 4.7 0.08 12.4 0.1 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.7 102414.1_23523120_1 - 0.0022 18.2 0.2 0.012 15.8 0.2 1.9 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Gal4_dimer PF03902.11 102414.1_23523120_1 - 0.45 10.6 1.9 1.4 9.0 0.3 2.1 1 1 1 2 2 2 0 Gal4-like dimerisation domain EF-hand_4 PF12763.5 102414.1_23523120_1 - 1.1 9.1 4.8 1.1 9.1 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.4 102415.1_23522120_3 - 2.1e-06 27.9 0.7 3.2e-06 27.4 0.7 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.30 102415.1_23522120_3 - 2.9e-05 23.2 0.7 0.00016 20.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.4 102415.1_23522120_3 - 0.00046 19.8 0.5 0.076 12.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.4 102415.1_23522120_3 - 0.052 13.2 0.5 0.096 12.3 0.3 1.5 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.4 102415.1_23522120_3 - 0.067 12.6 0.1 0.067 12.6 0.1 2.0 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.7 102415.1_23522120_3 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Gal4_dimer PF03902.11 102415.1_23522120_3 - 0.46 10.5 1.3 1.2 9.3 0.3 1.9 1 1 1 2 2 2 0 Gal4-like dimerisation domain Ham1p_like PF01725.14 073522.2_23522120_2 - 2.7e-43 147.7 0.0 3.4e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Ham1 family Tropomodulin PF03250.12 204774.1_23523001_3 - 1.3e-60 203.4 6.1 2.3e-60 202.6 6.1 1.4 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.4 204774.1_23523001_3 - 0.62 10.1 0.0 0.62 10.1 0.0 3.2 4 0 0 4 4 4 0 Leucine Rich repeat FOXP-CC PF16159.3 001311335.1_37525001_1 - 2e-35 121.1 4.2 2e-35 121.1 4.2 3.6 2 1 1 3 3 3 1 FOXP coiled-coil domain Forkhead PF00250.16 001311335.1_37525001_1 - 1.5e-27 95.6 0.1 4.1e-27 94.2 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain Bestrophin PF01062.19 001311335.1_37525001_1 - 0.18 11.0 0.0 0.18 11.0 0.0 2.5 3 0 0 3 3 3 0 Bestrophin, RFP-TM, chloride channel zf-C4 PF00105.16 001282896.1_37524001_3 - 4e-24 84.7 14.3 4e-24 84.7 14.3 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001282896.1_37524001_3 - 7.9e-11 41.8 0.4 7.9e-11 41.8 0.4 2.3 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Hormone_recep PF00104.28 001279472.1_37523001_1 - 2.9e-15 56.3 0.0 6.6e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Hormone_1 PF00103.18 001279528.1_37522001_1 - 3.1e-39 134.8 2.0 4e-39 134.5 2.0 1.1 1 0 0 1 1 1 1 Somatotropin hormone family HTH_Tnp_4 PF13613.4 001032429.1_12424001_3 - 0.035 13.8 0.1 3.1 7.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease zf-H2C2_2 PF13465.4 001128118.1_12424001_1 - 1.2e-18 66.5 21.6 2.7e-08 33.8 0.6 4.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.24 001128118.1_12424001_1 - 4.2e-14 52.0 22.8 3.8e-05 23.8 4.9 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001128118.1_12424001_1 - 2e-10 40.4 18.4 0.0016 19.0 3.1 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001128118.1_12424001_1 - 1.5e-06 27.9 10.6 0.00066 19.4 0.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001128118.1_12424001_1 - 0.00093 19.3 10.6 0.11 12.7 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001128118.1_12424001_1 - 0.011 15.9 17.3 0.012 15.8 1.2 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type BolA PF01722.16 001128118.1_12424001_1 - 0.037 14.2 1.5 0.13 12.4 0.7 2.3 2 0 0 2 2 2 0 BolA-like protein zf-RAG1 PF10426.7 001128118.1_12424001_1 - 0.048 13.7 0.2 0.74 9.9 0.0 2.8 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-Di19 PF05605.10 001128118.1_12424001_1 - 0.053 13.7 7.1 0.18 11.9 4.5 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.10 001128118.1_12424001_1 - 0.066 13.1 2.9 0.23 11.3 2.9 2.0 1 0 0 1 1 1 0 zinc-ribbons zf-C2H2_4 PF13894.4 001093742.1_12425001_1 - 0.11 13.2 6.2 1.9 9.4 0.2 3.6 2 0 0 2 2 2 0 C2H2-type zinc finger PAX PF00292.16 001032469.1_12424001_3 - 2e-69 231.1 0.4 3.1e-69 230.6 0.4 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.27 001032469.1_12424001_3 - 2e-21 75.4 4.3 3.7e-21 74.6 4.3 1.5 1 0 0 1 1 1 1 Homeobox domain HTH_Tnp_IS1 PF12759.5 001032469.1_12424001_3 - 0.00042 19.7 0.1 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 InsA C-terminal domain HTH_23 PF13384.4 001032469.1_12424001_3 - 0.0043 16.7 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain zf-C4 PF00105.16 001032486.1_12425001_2 - 1.3e-27 95.9 21.4 2e-27 95.3 19.4 2.3 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001032486.1_12425001_2 - 4.8e-18 65.4 0.9 1.2e-17 64.0 0.9 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor IL17 PF06083.9 001129874.1_12422001_1 - 7.1e-22 77.6 2.4 7.1e-22 77.6 2.4 2.2 2 1 0 2 2 2 1 Interleukin-17 zf-C2H2 PF00096.24 001078460.1_12423001_2 - 4.1e-05 23.7 34.1 0.22 11.9 5.6 6.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type Vps36-NZF-N PF16988.3 001078460.1_12423001_2 - 0.0001 21.5 4.4 0.00033 19.8 0.1 2.8 3 0 0 3 3 3 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3505 PF12013.6 001078460.1_12423001_2 - 0.00043 20.6 25.1 0.62 10.4 2.6 4.7 2 2 2 4 4 4 4 Protein of unknown function (DUF3505) zf-C2H2_4 PF13894.4 001078460.1_12423001_2 - 0.001 19.6 33.9 0.61 10.9 4.7 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001078460.1_12423001_2 - 0.009 16.3 0.1 0.009 16.3 0.1 5.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-Mss51 PF13824.4 001078460.1_12423001_2 - 0.21 11.6 0.1 0.21 11.6 0.1 3.2 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-NADH-PPase PF09297.9 001078460.1_12423001_2 - 4.6 6.9 8.8 1.3 8.6 0.1 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Neur_chan_memb PF02932.14 001204049.1_12424001_1 - 2.6e-87 292.7 7.2 6e-87 291.5 7.2 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.21 001204049.1_12424001_1 - 1.6e-73 246.6 4.0 2.3e-73 246.1 4.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain RIIa PF02197.15 001159764.1_12422001_1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Forkhead PF00250.16 001078525.1_12428001_1 - 3.8e-29 100.7 0.9 1e-28 99.4 0.9 1.8 1 0 0 1 1 1 1 Forkhead domain PBC PF03792.11 001078535.1_12425001_3 - 7.4e-87 289.9 3.0 1.2e-86 289.2 3.0 1.3 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.27 001078535.1_12425001_3 - 2.6e-18 65.4 1.6 5e-18 64.5 1.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001078535.1_12425001_3 - 7.2e-15 54.5 0.0 1.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.3 001078535.1_12425001_3 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT IRF PF00605.15 001078274.1_12424001_3 - 4.9e-40 135.9 0.0 1.2e-39 134.7 0.0 1.7 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor DUF972 PF06156.11 001078274.1_12424001_3 - 0.016 15.7 7.0 0.22 12.0 1.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) HMMR_C PF15908.3 001078274.1_12424001_3 - 0.03 14.5 1.6 0.056 13.6 1.6 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal ZapB PF06005.10 001078274.1_12424001_3 - 0.039 14.3 7.3 9.1 6.7 0.1 3.5 3 0 0 3 3 3 0 Cell division protein ZapB TMCO5 PF14992.4 001078274.1_12424001_3 - 0.092 12.2 8.4 0.013 14.9 3.8 1.8 2 0 0 2 2 2 0 TMCO5 family Fez1 PF06818.13 001078274.1_12424001_3 - 0.31 11.3 13.2 0.98 9.7 13.2 1.8 1 1 0 1 1 1 0 Fez1 GAS PF13851.4 001078274.1_12424001_3 - 0.78 8.9 7.1 2.4 7.3 7.2 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CC2-LZ PF16516.3 001078274.1_12424001_3 - 7 6.9 10.3 42 4.4 10.3 2.2 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Ras PF00071.20 001032615.1_12422001_3 - 7.4e-55 184.8 0.0 8.7e-55 184.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001032615.1_12422001_3 - 2.4e-21 76.1 0.0 3.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001032615.1_12422001_3 - 5.9e-09 35.5 0.0 7.5e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DP PF08781.8 001303399.1_27623001_3 - 2.7e-63 211.8 1.3 6.1e-63 210.7 1.3 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.18 001303399.1_27623001_3 - 2.9e-26 91.2 0.2 6.4e-26 90.0 0.2 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DRY_EERY PF09750.7 001303399.1_27623001_3 - 0.053 13.6 0.7 0.1 12.7 0.7 1.4 1 0 0 1 1 1 0 Alternative splicing regulator HSP20 PF00011.19 001303311.1_27623001_1 - 1.4e-22 79.6 0.1 2.8e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.16 001303311.1_27623001_1 - 0.0056 16.7 0.6 0.014 15.5 0.6 1.7 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal YabP PF07873.9 001303311.1_27623001_1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 YabP family GvpO PF05800.9 001303311.1_27623001_1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Ras PF00071.20 001303394.1_27622001_1 - 3.2e-66 221.8 0.5 3.9e-66 221.5 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001303394.1_27622001_1 - 5.7e-34 116.8 0.1 9.8e-34 116.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001303394.1_27622001_1 - 8.8e-17 61.0 0.5 1.1e-16 60.6 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001303394.1_27622001_1 - 3.8e-06 26.3 0.2 5e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001303394.1_27622001_1 - 0.00016 21.1 0.1 0.00022 20.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.25 001303394.1_27622001_1 - 0.00065 19.1 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001303394.1_27622001_1 - 0.0027 17.6 0.1 0.0048 16.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001303394.1_27622001_1 - 0.013 15.3 0.1 4 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF3963 PF13124.4 001303394.1_27622001_1 - 0.028 14.3 0.8 0.054 13.3 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_16 PF13191.4 001303394.1_27622001_1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain GILT PF03227.14 001303352.1_27623001_2 - 3.6e-29 101.0 1.1 9.4e-29 99.6 1.1 1.8 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) SapA PF02199.13 001303352.1_27623001_2 - 9.4e-05 22.4 1.7 9.4e-05 22.4 1.7 2.2 2 0 0 2 2 2 1 Saposin A-type domain Ras PF00071.20 001303375.1_27623001_3 - 2.1e-49 167.1 0.0 2.6e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001303375.1_27623001_3 - 1.7e-30 105.6 0.0 2.8e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001303375.1_27623001_3 - 6e-10 38.7 0.0 8.4e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001303375.1_27623001_3 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.6 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001303375.1_27623001_3 - 0.0012 18.3 0.2 0.0056 16.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RNA_helicase PF00910.20 001303375.1_27623001_3 - 0.0015 18.8 0.2 0.0087 16.3 0.2 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.10 001303375.1_27623001_3 - 0.0043 16.3 0.0 0.0056 15.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.4 001303375.1_27623001_3 - 0.024 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.10 001303375.1_27623001_3 - 0.058 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ArgoMid PF16487.3 001303375.1_27623001_3 - 0.06 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute TsaE PF02367.15 001303375.1_27623001_3 - 0.065 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.18 001303375.1_27623001_3 - 0.098 11.7 1.6 2.9 6.8 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit SRPRB PF09439.8 001303375.1_27623001_3 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.14 001303375.1_27623001_3 - 0.14 11.9 0.1 8.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.4 001303375.1_27623001_3 - 0.16 12.2 0.1 0.26 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain Insulin PF00049.16 001303334.1_27625001_1 - 3.9e-13 50.1 6.5 3.3e-06 27.9 2.6 2.8 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family Peptidase_M23 PF01551.20 001303395.1_27622001_3 - 2.8e-05 24.1 0.0 5.3e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M23 AhpC-TSA PF00578.19 001303379.1_27622001_3 - 5.1e-35 119.9 0.0 8.6e-35 119.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.7 001303379.1_27622001_3 - 3.9e-13 48.9 0.1 9.3e-13 47.7 0.0 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.8 001303379.1_27622001_3 - 2.2e-12 46.8 0.0 4e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin SRCR PF00530.16 001303324.1_27624001_1 - 1.1e-30 105.9 2.9 1.1e-30 105.9 2.9 2.1 2 1 0 2 2 2 1 Scavenger receptor cysteine-rich domain Collagen PF01391.16 001303324.1_27624001_1 - 6.8e-14 51.2 59.6 1.2e-08 34.4 28.8 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) SRCR_2 PF15494.4 001303324.1_27624001_1 - 5.2e-06 26.8 0.1 2.2e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1664 PF07889.10 001303324.1_27624001_1 - 0.14 12.0 2.9 0.96 9.3 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) FOXP-CC PF16159.3 001282893.1_37523001_3 - 7.9e-30 103.2 0.8 2.3e-29 101.7 0.8 1.9 1 0 0 1 1 1 1 FOXP coiled-coil domain Forkhead PF00250.16 001282893.1_37523001_3 - 1.6e-26 92.3 0.3 4.4e-26 90.9 0.3 1.8 1 0 0 1 1 1 1 Forkhead domain NSP2-B_epitope PF14757.4 001282893.1_37523001_3 - 0.043 13.4 0.3 0.077 12.5 0.3 1.3 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Cpn60_TCP1 PF00118.22 001279708.1_37524001_1 - 9.5e-150 499.3 10.3 1.1e-149 499.1 10.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2529 PF10740.7 001279708.1_37524001_1 - 0.016 14.7 0.2 0.041 13.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) Peptidase_S10 PF00450.20 001311320.1_37523001_1 - 2.4e-133 445.5 0.5 2.7e-133 445.3 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ACTH_domain PF00976.16 001287606.2_01423001_3 - 8e-24 83.0 28.1 5.8e-09 35.5 0.7 4.0 4 0 0 4 4 4 3 Corticotropin ACTH domain NPP PF08384.8 001287606.2_01423001_3 - 1.9e-23 82.1 1.1 4.4e-23 80.9 1.1 1.7 1 0 0 1 1 1 1 Pro-opiomelanocortin, N-terminal region Op_neuropeptide PF08035.9 001287606.2_01423001_3 - 7.5e-16 57.6 0.3 1.6e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 Opioids neuropeptide HSP90 PF00183.16 001287265.1_01426001_2 - 2.2e-228 759.1 33.1 2.2e-228 759.1 33.1 2.0 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.24 001287265.1_01426001_2 - 3e-15 56.6 0.6 5.5e-15 55.8 0.6 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001287265.1_01426001_2 - 2.6e-12 46.6 0.4 9.1e-12 44.8 0.4 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Presenilin PF01080.15 001287265.1_01426001_2 - 6.7 5.2 5.5 15 4.0 0.9 2.4 2 0 0 2 2 2 0 Presenilin HSP70 PF00012.18 001287291.1_01426001_3 - 2.3e-268 891.2 9.8 2.8e-268 891.0 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001287291.1_01426001_3 - 7.6e-17 61.0 0.9 1.9e-14 53.1 0.1 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.14 001287291.1_01426001_3 - 3.1e-05 23.7 0.1 7.9e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.4 001287291.1_01426001_3 - 0.17 12.2 5.8 14 6.0 0.1 3.8 3 1 0 3 3 3 0 Cell division protein FtsA ERbeta_N PF12497.6 001287264.1_01424001_1 - 9e-55 183.2 11.4 1.6e-54 182.4 11.4 1.4 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.28 001287264.1_01424001_1 - 3.6e-36 124.6 1.8 5.3e-36 124.0 1.8 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001287264.1_01424001_1 - 1.4e-31 108.6 13.4 3.1e-31 107.5 13.4 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001317143.1_01423001_3 - 1.5e-40 138.9 0.0 2.5e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.6 001317143.1_01423001_3 - 2.8e-40 136.8 20.5 4.2e-40 136.2 20.5 1.3 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.16 001317143.1_01423001_3 - 3.7e-32 110.5 16.3 6.1e-32 109.8 16.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RRM_1 PF00076.20 001287301.1_01423001_3 - 2.5e-25 87.9 0.1 3.9e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001287301.1_01423001_3 - 0.00055 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.3 001287301.1_01423001_3 - 0.0025 17.5 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-C4 PF00105.16 001287311.2_01423001_2 - 6.9e-30 103.2 16.2 1.3e-29 102.3 16.2 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001287311.2_01423001_2 - 4.7e-17 62.1 0.1 1.2e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Neur_chan_LBD PF02931.21 001323297.1_40829001_1 - 9.9e-73 244.0 1.1 1.3e-72 243.6 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001323297.1_40829001_1 - 1.4e-64 218.3 0.0 1.8e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Abhydrolase_1 PF00561.18 001303226.1_30823001_1 - 1.4e-21 77.2 0.0 6.1e-21 75.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001303226.1_30823001_1 - 3.9e-18 66.7 0.0 5.1e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001303226.1_30823001_1 - 1.3e-12 47.4 0.0 1.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.12 001303226.1_30823001_1 - 0.00038 19.1 0.0 0.0014 17.3 0.0 1.8 2 0 0 2 2 2 1 Ndr family DUF1071 PF06378.9 001303226.1_30823001_1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Abhydrolase_3 PF07859.11 001303226.1_30823001_1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Asp2 PF16929.3 001303226.1_30823001_1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Ras PF00071.20 001303203.1_30823001_1 - 2.4e-55 186.4 0.3 3.2e-55 186.0 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001303203.1_30823001_1 - 1e-19 70.8 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001303203.1_30823001_1 - 2.4e-08 33.5 0.1 3.1e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001303203.1_30823001_1 - 0.00034 20.1 0.1 0.0008 18.9 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001303203.1_30823001_1 - 0.0046 16.9 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.18 001303203.1_30823001_1 - 0.0055 15.8 0.0 0.02 13.9 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit DUF258 PF03193.14 001303203.1_30823001_1 - 0.0078 16.0 1.7 2.9 7.6 0.0 2.3 1 1 0 2 2 2 2 Protein of unknown function, DUF258 Troponin PF00992.18 001303214.1_30822001_1 - 4.7e-33 114.2 45.7 9.4e-32 110.0 34.5 2.6 2 1 1 3 3 3 2 Troponin IncA PF04156.12 001303214.1_30822001_1 - 2.3 7.8 26.5 2.2 7.9 2.3 2.3 2 0 0 2 2 2 0 IncA protein ELO PF01151.16 001303148.1_30822001_1 - 3.6e-67 226.4 26.5 4.5e-67 226.1 26.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Nfu_N PF08712.9 001006305.2_23522001_3 - 1.1e-34 118.2 0.0 2.2e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.15 001006305.2_23522001_3 - 1.4e-25 89.1 0.1 2.2e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain FGGY_N PF00370.19 001096930.1_53424001_1 - 7.6e-25 87.8 0.0 7.5e-24 84.5 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF4445 PF14574.4 001096930.1_53424001_1 - 0.038 12.4 0.0 0.13 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4445) DDHD PF02862.15 001086336.2_53423001_1 - 2.4 8.1 10.4 3.4 7.6 10.4 1.2 1 0 0 1 1 1 0 DDHD domain Trypsin PF00089.24 001086336.2_53423001_2 - 2e-67 227.1 1.5 3.2e-67 226.4 1.5 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001086336.2_53423001_2 - 8.6e-06 26.0 0.1 1.9e-05 24.9 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001086336.2_53423001_2 - 7.5e-05 23.5 0.2 0.00015 22.5 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DDHD PF02862.15 001086336.2_53423001_2 - 0.02 14.9 4.2 0.025 14.6 4.2 1.2 1 0 0 1 1 1 0 DDHD domain EOS1 PF12326.6 001086336.2_53423001_2 - 0.17 11.7 5.3 0.24 11.2 5.3 1.3 1 0 0 1 1 1 0 N-glycosylation protein Connexin PF00029.17 001086336.2_53423001_2 - 0.39 10.3 14.3 0.6 9.7 14.3 1.4 1 0 0 1 1 1 0 Connexin RNA_pol_Rpc4 PF05132.12 001086336.2_53423001_2 - 0.96 9.8 19.4 1.4 9.2 19.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 EOS1 PF12326.6 001086336.2_53423001_3 - 0.0076 16.1 0.3 0.01 15.7 0.3 1.3 1 0 0 1 1 1 1 N-glycosylation protein Peroxin-13_N PF04088.11 001086336.2_53423001_3 - 1.6 8.9 5.5 2.4 8.3 5.5 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Thioredoxin_7 PF13899.4 001286926.1_41121001_1 - 6.4e-25 87.0 0.3 1.4e-24 86.0 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.4 001286926.1_41121001_1 - 3.1e-06 27.5 0.2 9.4e-06 25.9 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.13 001286926.1_41121001_1 - 7.8e-06 25.8 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 TAP42 PF04177.10 001286926.1_41121001_1 - 0.079 11.9 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 TAP42-like family 7tm_1 PF00001.19 001297452.1_43023001_1 - 1.8e-36 125.6 14.4 2.5e-36 125.1 14.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.7 001297452.1_43023001_1 - 2.5e-05 23.6 1.2 2.5e-05 23.6 1.2 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw Cytochrom_B_N_2 PF13631.4 001297452.1_43023001_1 - 0.0015 18.4 1.9 0.0026 17.6 0.1 2.2 2 1 1 3 3 3 1 Cytochrome b(N-terminal)/b6/petB 7TM_GPCR_Srsx PF10320.7 001297452.1_43023001_1 - 0.0031 16.8 9.5 0.16 11.2 0.3 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001297452.1_43023001_1 - 0.066 12.8 12.2 1.1 8.9 12.2 2.2 1 1 0 1 1 1 0 Olfactory receptor DUF4190 PF13828.4 001297452.1_43023001_1 - 4.1 7.1 9.5 1.1 8.9 2.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) GST_N PF02798.18 001329371.1_27322001_1 - 2.1e-14 53.5 0.0 4.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001329371.1_27322001_1 - 2.7e-14 53.2 0.0 5.7e-14 52.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001329371.1_27322001_1 - 1.1e-10 41.6 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001329371.1_27322001_1 - 5.2e-08 32.9 0.0 8.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001329371.1_27322001_1 - 9.1e-08 32.1 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001329371.1_27322001_1 - 0.0037 17.1 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 001329371.1_27322001_1 - 0.13 12.3 0.0 0.72 10.0 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin A2M_comp PF07678.12 001172060.1_53429001_3 - 8.2e-89 297.2 0.2 1.2e-88 296.6 0.2 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.12 001172060.1_53429001_3 - 2.2e-29 102.4 0.3 1.7e-25 89.9 0.0 3.3 2 1 0 2 2 2 2 Alpha-2-macroglobulin family N-terminal region A2M PF00207.20 001172060.1_53429001_3 - 9.1e-29 99.0 0.1 2.4e-28 97.7 0.1 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.12 001172060.1_53429001_3 - 1.6e-26 92.8 0.5 5.2e-26 91.1 0.5 2.0 1 0 0 1 1 1 1 A-macroglobulin receptor A2M_N PF01835.17 001172060.1_53429001_3 - 2.7e-20 72.5 0.0 1.5e-19 70.1 0.0 2.4 2 0 0 2 2 2 1 MG2 domain Thiol-ester_cl PF10569.7 001172060.1_53429001_3 - 1.6e-14 53.1 1.7 4.1e-14 51.8 1.7 1.8 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region CarboxypepD_reg PF13620.4 001172060.1_53429001_3 - 0.0032 17.6 1.3 0.014 15.5 0.3 2.8 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Prenyltrans PF00432.19 001172060.1_53429001_3 - 0.034 13.8 0.6 0.54 9.9 0.2 3.3 3 1 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat SVA PF05326.9 001172060.1_53429001_3 - 0.068 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) Thioredoxin_7 PF13899.4 001286930.1_41122001_1 - 3.2e-24 84.8 0.0 6.5e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.4 001286930.1_41122001_1 - 0.0062 16.8 0.1 0.048 14.0 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain HycA_repressor PF11046.6 001286930.1_41122001_1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons Pkinase_Tyr PF07714.15 204996.3_23528001_2 - 1e-137 457.5 0.0 2.4e-79 266.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.23 204996.3_23528001_2 - 5.2e-73 245.5 0.0 8.1e-50 169.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SH2 PF00017.22 204996.3_23528001_2 - 1.5e-06 28.1 0.0 4.1e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.4 204996.3_23528001_2 - 0.00087 18.5 0.0 0.19 10.9 0.0 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.21 204996.3_23528001_2 - 0.014 15.1 0.2 0.12 12.2 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family FERM_M PF00373.16 204996.3_23528001_2 - 0.11 12.8 0.0 0.42 10.9 0.0 2.0 3 0 0 3 3 3 0 FERM central domain RIO1 PF01163.20 204996.3_23528001_2 - 0.2 11.1 0.2 0.78 9.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Sod_Cu PF00080.18 001303360.1_27621001_1 - 4.2e-49 166.2 4.8 4.9e-49 166.0 4.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ald_Xan_dh_C2 PF02738.16 001303285.1_30829001_1 - 2.6e-184 613.6 0.0 3.8e-184 613.0 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001303285.1_30829001_1 - 3e-38 131.1 0.0 5.7e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.15 001303285.1_30829001_1 - 2.2e-30 104.7 0.0 5.4e-29 100.3 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.20 001303285.1_30829001_1 - 1.3e-29 102.6 1.6 2.7e-29 101.6 1.6 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001303285.1_30829001_1 - 4.9e-28 96.8 0.2 1.2e-27 95.5 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.25 001303285.1_30829001_1 - 1.8e-08 34.1 1.0 4.3e-07 29.6 0.1 2.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001303285.1_30829001_1 - 0.034 13.8 2.4 0.096 12.4 2.4 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B p450 PF00067.20 001303202.1_30824001_3 - 9.3e-109 364.1 0.2 1.1e-108 363.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_C_3 PF14497.4 001303153.1_30822001_3 - 3.7e-18 65.4 0.0 6.6e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001303153.1_30822001_3 - 9e-18 64.3 0.0 2.3e-17 62.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001303153.1_30822001_3 - 3.2e-14 52.8 0.0 5.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001303153.1_30822001_3 - 0.0039 17.4 0.0 0.021 15.1 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_4 PF14834.4 001303153.1_30822001_3 - 0.037 14.3 0.0 0.073 13.3 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001303153.1_30822001_3 - 0.17 11.8 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IL4 PF00727.16 001303181.1_30821001_1 - 5e-09 36.2 0.6 7.2e-09 35.7 0.6 1.3 1 0 0 1 1 1 1 Interleukin 4 IL13 PF03487.11 001303181.1_30821001_1 - 3.4e-08 33.3 0.5 4.2e-08 33.0 0.5 1.1 1 0 0 1 1 1 1 Interleukin-13 IL8 PF00048.18 001303219.1_30821001_1 - 3.3e-17 62.3 0.6 4e-17 62.0 0.6 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like 7tm_1 PF00001.19 001297490.1_43023001_3 - 1.5e-38 132.5 9.3 1.8e-38 132.2 9.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.7 001297490.1_43023001_3 - 4.8e-05 22.7 8.0 4.8e-05 22.7 8.0 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.7 001297490.1_43023001_3 - 0.001 18.4 12.4 0.0026 17.0 12.4 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001297490.1_43023001_3 - 0.16 11.5 6.8 0.092 12.3 0.4 2.2 2 0 0 2 2 2 0 Olfactory receptor 7TM_GPCR_Srsx PF10320.7 001297490.1_43023001_3 - 1.5 8.0 12.5 3.2 6.9 12.5 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2070 PF09843.7 001297490.1_43023001_3 - 2.3 6.3 6.6 3.6 5.6 6.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 7tm_1 PF00001.19 001310074.1_30523001_1 - 3.5e-41 141.1 12.1 4.5e-41 140.7 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001310074.1_30523001_1 - 1.6e-07 30.9 13.4 3.5e-07 29.7 13.4 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Rhodopsin_N PF10413.7 001310074.1_30523001_1 - 0.012 15.3 0.4 0.035 13.8 0.4 1.8 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin SAP PF02037.25 001030603.2_23524001_1 - 2.1e-10 40.0 0.2 5.3e-10 38.7 0.2 1.7 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.4 001030603.2_23524001_1 - 8e-09 35.1 8.2 8e-09 35.1 8.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001030603.2_23524001_1 - 4.8e-07 29.4 9.7 4.8e-07 29.4 9.7 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.4 001030603.2_23524001_1 - 1.8e-06 27.5 5.4 1.8e-06 27.5 5.4 3.0 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.4 001030603.2_23524001_1 - 1.2e-05 24.9 12.3 4e-05 23.3 9.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001030603.2_23524001_1 - 7.7e-05 22.8 12.2 7.7e-05 22.8 12.2 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.4 001030603.2_23524001_1 - 0.0038 17.0 18.0 0.0039 17.0 13.1 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001030603.2_23524001_1 - 0.0042 16.9 10.4 0.0042 16.9 10.4 2.5 3 0 0 3 3 2 1 RING-type zinc-finger PRP21_like_P PF12230.6 001030603.2_23524001_1 - 0.0071 16.1 0.1 0.0071 16.1 0.1 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein zf-RING_10 PF16685.3 001030603.2_23524001_1 - 0.019 15.0 5.7 0.074 13.1 5.7 2.1 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.5 001030603.2_23524001_1 - 0.021 14.9 8.1 0.021 14.9 8.1 3.1 3 0 0 3 3 3 0 RING-H2 zinc finger domain LEM PF03020.13 001030603.2_23524001_1 - 0.065 12.7 0.3 0.13 11.7 0.3 1.4 1 0 0 1 1 1 0 LEM domain GAT PF03127.12 001030603.2_23524001_1 - 0.25 11.5 3.2 1.3 9.2 0.1 3.1 2 1 2 4 4 4 0 GAT domain zf-C3HC4_2 PF13923.4 001123467.1_53524001_3 - 5.5e-12 45.2 10.9 1.1e-11 44.2 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001123467.1_53524001_3 - 2.9e-09 36.9 8.4 6.1e-09 35.9 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.23 001123467.1_53524001_3 - 2e-08 33.9 11.6 4.4e-08 32.7 11.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001123467.1_53524001_3 - 1.4e-07 31.1 7.3 2.5e-07 30.3 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001123467.1_53524001_3 - 2.5e-07 30.5 6.6 5.5e-07 29.4 6.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.5 001123467.1_53524001_3 - 6e-05 23.1 8.9 0.00017 21.6 8.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.4 001123467.1_53524001_3 - 8.9e-05 22.2 10.8 0.00039 20.2 11.2 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.6 001123467.1_53524001_3 - 0.0024 17.5 5.5 0.0048 16.6 5.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.4 001123467.1_53524001_3 - 0.0033 17.1 10.2 0.069 12.9 10.1 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.3 001123467.1_53524001_3 - 0.0051 16.8 4.0 0.013 15.5 4.0 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.5 001123467.1_53524001_3 - 0.016 15.1 2.9 0.048 13.6 2.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.3 001123467.1_53524001_3 - 0.016 14.8 6.1 0.038 13.6 6.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.4 001123467.1_53524001_3 - 0.021 14.8 9.3 0.05 13.6 9.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.4 001123467.1_53524001_3 - 0.22 11.1 9.8 0.75 9.4 9.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.4 001123467.1_53524001_3 - 0.36 10.6 2.8 0.91 9.3 2.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.9 001123467.1_53524001_3 - 0.72 9.9 7.3 0.68 9.9 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-P11 PF03854.12 001123467.1_53524001_3 - 1.4 8.5 6.4 14 5.3 7.0 2.4 2 1 0 2 2 2 0 P-11 zinc finger DZR PF12773.5 001123467.1_53524001_3 - 2 8.4 7.3 4.9 7.1 7.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon GST_C_3 PF14497.4 001304130.1_21522001_1 - 1.1e-15 57.5 0.0 1.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001304130.1_21522001_1 - 1.9e-12 47.1 0.0 3.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001304130.1_21522001_1 - 2.6e-09 37.2 0.0 5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001304130.1_21522001_1 - 0.001 18.9 0.0 0.0033 17.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Proteasome PF00227.24 001304159.1_21523001_3 - 3.1e-46 157.1 0.0 3.8e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.6 001304159.1_21523001_3 - 2.2e-16 58.8 0.6 4.4e-16 57.9 0.6 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal UBX PF00789.18 001310871.1_21524001_3 - 1.5e-08 34.6 0.0 3.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Neurensin PF14927.4 001310871.1_21524001_3 - 0.038 13.6 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Neurensin GST_C_3 PF14497.4 001304128.1_21523001_1 - 3.7e-21 75.0 0.3 6.7e-21 74.2 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001304128.1_21523001_1 - 3e-11 43.2 0.0 6.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001304128.1_21523001_1 - 2.4e-10 40.5 0.0 4.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001304128.1_21523001_1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MYEOV2 PF15004.4 102421.1_23523120_2 - 2.5e-32 111.0 6.9 3.5e-32 110.4 6.9 1.2 1 0 0 1 1 1 1 Myeloma-overexpressed-like MYEOV2 PF15004.4 102420.1_23523120_2 - 2.9e-32 110.7 6.9 4.1e-32 110.3 6.9 1.2 1 0 0 1 1 1 1 Myeloma-overexpressed-like NTF2 PF02136.18 001303647.1_21522001_3 - 1.4e-31 109.4 0.2 2e-31 108.9 0.2 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.4 001303647.1_21522001_3 - 0.055 13.7 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Annexin PF00191.18 001304049.1_21523001_1 - 2e-89 293.5 12.9 5.5e-24 83.9 0.3 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.3 001304049.1_21523001_1 - 0.0032 17.2 0.2 0.87 9.4 0.0 3.0 3 0 0 3 3 3 2 Myb DNA-binding like DUF2312 PF10073.7 001304049.1_21523001_1 - 0.015 14.8 0.4 0.37 10.3 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) GST_N PF02798.18 001304221.1_21523001_2 - 1.5e-19 69.9 0.0 2.5e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001304221.1_21523001_2 - 2.8e-19 69.0 0.4 4.8e-19 68.3 0.4 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001304221.1_21523001_2 - 2.8e-12 46.6 0.1 4.5e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001304221.1_21523001_2 - 4.5e-05 23.0 0.6 9.7e-05 22.0 0.6 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001304221.1_21523001_2 - 0.0019 18.4 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001304221.1_21523001_2 - 0.012 15.4 0.1 0.053 13.3 0.1 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001304221.1_21523001_2 - 0.067 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain UNC-50 PF05216.11 001304066.1_21523001_1 - 1.9e-87 292.3 19.3 2.3e-87 292.0 19.3 1.1 1 0 0 1 1 1 1 UNC-50 family WD40 PF00400.30 001303743.1_21523001_1 - 4.6e-33 112.6 11.6 0.00012 22.7 0.1 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001303743.1_21523001_1 - 1e-10 41.7 1.0 0.0029 17.7 0.1 5.2 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001303743.1_21523001_1 - 0.00029 19.8 0.2 6.4 5.5 0.0 4.2 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.9 001303743.1_21523001_1 - 0.01 15.5 0.2 0.46 10.0 0.0 2.7 2 1 1 3 3 3 1 TUP1-like enhancer of split Nup160 PF11715.6 001303743.1_21523001_1 - 0.028 12.9 2.0 13 4.1 0.0 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 HPS3_N PF14761.4 001303743.1_21523001_1 - 0.14 11.6 0.0 0.53 9.8 0.1 1.8 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 LRR_8 PF13855.4 001323498.1_23926001_3 - 1.7e-48 162.1 60.2 2.3e-15 56.0 3.3 4.8 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.5 001323498.1_23926001_3 - 5.3e-15 55.1 35.5 1.9e-05 24.8 1.2 5.7 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001323498.1_23926001_3 - 1.3e-11 44.5 0.0 1e-07 31.8 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001323498.1_23926001_3 - 4e-06 26.3 3.7 0.038 13.4 0.1 2.9 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.31 001323498.1_23926001_3 - 2.7 8.7 34.7 2.5 8.8 0.1 8.0 7 1 1 8 8 8 0 Leucine Rich Repeat AMP-binding PF00501.26 001303293.1_36025001_1 - 1.4e-107 359.7 0.0 1.8e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001303293.1_36025001_1 - 0.0016 19.3 0.0 0.0035 18.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Insulin PF00049.16 001098641.1_50021001_1 - 1.1e-07 32.6 2.7 7.9e-07 29.9 2.7 2.1 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001098641.1_50021001_1 - 0.0011 18.8 4.3 0.53 10.2 0.1 2.3 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type Globin PF00042.20 001303298.1_36022001_1 - 1.5e-26 93.0 0.0 2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Globin Globin PF00042.20 001303294.1_36022001_2 - 2.7e-19 69.6 0.0 4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Globin Arf PF00025.19 001016111.2_53525001_2 - 1.4e-44 151.5 0.1 1.9e-44 151.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.20 001016111.2_53525001_2 - 4e-16 58.9 0.0 5.5e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001016111.2_53525001_2 - 1e-14 54.7 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.10 001016111.2_53525001_2 - 2.6e-07 30.1 0.0 3.6e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.18 001016111.2_53525001_2 - 1.5e-06 27.5 0.1 0.00022 20.4 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.8 001016111.2_53525001_2 - 1.3e-05 24.6 0.0 1.8e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001016111.2_53525001_2 - 0.0016 18.4 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase VirE PF05272.9 001016111.2_53525001_2 - 0.026 14.1 0.3 0.57 9.7 0.1 2.1 2 0 0 2 2 2 0 Virulence-associated protein E Na_Ca_ex PF01699.22 001323798.1_35924001_1 - 3.5e-48 163.3 45.3 1.8e-28 99.3 18.2 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DSPc PF00782.18 001016109.2_53526001_1 - 5e-46 155.7 0.2 7.2e-46 155.2 0.2 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.18 001016109.2_53526001_1 - 1.1e-07 32.2 0.0 2.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.25 001016109.2_53526001_1 - 5.4e-06 26.0 0.0 8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.10 001016109.2_53526001_1 - 0.024 14.2 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.4 001016109.2_53526001_1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate PNP_UDP_1 PF01048.18 001323790.1_35922001_1 - 1e-40 139.3 0.0 1.2e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily HSP90 PF00183.16 001323197.1_13926001_1 - 6.6e-230 764.2 28.7 1.4e-229 763.2 28.7 1.5 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.24 001323197.1_13926001_1 - 3.2e-15 56.5 0.5 5.9e-15 55.7 0.5 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001323197.1_13926001_1 - 2.5e-12 46.7 0.4 8.3e-12 45.0 0.4 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3408 PF11888.6 001323197.1_13926001_1 - 8.5 6.4 15.4 6 6.9 3.9 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Peptidase_M20 PF01546.26 001279542.1_37524001_3 - 2.4e-35 122.0 0.0 3.2e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.12 001279542.1_37524001_3 - 2.1e-15 56.4 0.0 3.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain WG_beta_rep PF14903.4 001279542.1_37524001_3 - 0.035 14.3 0.0 0.27 11.4 0.0 2.3 2 0 0 2 2 2 0 WG containing repeat Glyco_transf_10 PF00852.17 001032525.1_12424001_3 - 2.5e-47 160.7 0.6 4.2e-47 160.0 0.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.3 001032525.1_12424001_3 - 5.7e-25 87.8 0.4 1.1e-24 86.9 0.4 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal NO_synthase PF02898.13 001303213.1_30829001_3 - 6.6e-190 630.7 0.1 1e-189 630.1 0.1 1.3 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.18 001303213.1_30829001_3 - 3.7e-69 232.5 0.0 6e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.23 001303213.1_30829001_3 - 3.8e-43 147.0 0.0 7.6e-43 146.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.19 001303213.1_30829001_3 - 1.7e-21 76.8 0.0 4.4e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.10 001303213.1_30829001_3 - 0.051 13.5 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF1400 PF07176.9 001303213.1_30829001_3 - 0.14 12.3 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Hormone_1 PF00103.18 001279786.1_37523001_3 - 1.1e-28 100.3 0.1 1.6e-28 99.8 0.1 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Vitellogenin_N PF01347.20 001323180.1_42829001_2 - 2.2e-172 574.6 0.5 2.2e-172 574.6 0.5 2.2 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.9 001323180.1_42829001_2 - 5.5e-57 193.2 0.0 5.5e-57 193.2 0.0 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF1943) DUF1944 PF09175.8 001323180.1_42829001_2 - 2.7e-52 176.8 0.1 5.2e-52 175.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) VWD PF00094.23 001323180.1_42829001_2 - 6.6e-21 75.1 0.1 1.8e-20 73.7 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type D domain SPX PF03105.17 001323180.1_42829001_2 - 4.3 7.1 35.3 7.4 6.3 35.3 1.3 1 0 0 1 1 1 0 SPX domain 7tm_1 PF00001.19 001287458.2_22325001_1 - 5.6e-60 202.7 22.1 7.8e-60 202.2 22.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001287458.2_22325001_1 - 5.1e-10 39.0 22.6 8.6e-10 38.3 22.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx T4_deiodinase PF00837.15 001308654.1_30823001_2 - 8.1e-81 270.6 0.0 1.1e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase Zona_pellucida PF00100.21 001323210.1_13923001_1 - 2.5e-46 158.3 0.0 3.1e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain VWD PF00094.23 001267630.1_23628001_1 - 1e-28 100.5 6.8 2.8e-18 66.6 0.4 2.3 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.9 001267630.1_23628001_1 - 2.7e-16 59.6 12.4 3.4e-14 52.9 0.5 3.3 3 0 0 3 3 3 2 C8 domain VWC PF00093.16 001267630.1_23628001_2 - 1.7e-05 24.9 10.8 1.7e-05 24.9 10.8 6.5 4 1 3 7 7 7 2 von Willebrand factor type C domain Telomerase_RBD PF12009.6 001323235.1_13929001_1 - 5.6e-42 142.9 3.6 1.5e-41 141.4 3.6 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.25 001323235.1_13929001_1 - 1.8e-13 50.4 0.0 6.3e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Lipoprotein_11 PF03260.11 001323235.1_13929001_1 - 0.033 13.4 0.1 0.07 12.4 0.1 1.5 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein SelK_SelG PF10961.6 001308659.1_30822001_3 - 3e-28 98.1 0.9 5.1e-28 97.4 0.9 1.4 1 0 0 1 1 1 1 Selenoprotein SelK_SelG HSP90 PF00183.16 001323196.1_13926001_3 - 7.6e-242 803.6 31.2 9.6e-242 803.2 31.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.24 001323196.1_13926001_3 - 2e-12 47.6 0.0 4.3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001323196.1_13926001_3 - 3.8e-10 39.6 0.1 1e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 4F5 PF04419.12 001016744.1_53524001_2 - 4.1e-09 37.0 16.2 4.1e-09 37.0 16.2 1.7 2 0 0 2 2 2 1 4F5 protein family zf-met PF12874.5 001016744.1_53524001_2 - 0.00064 19.9 0.1 0.00064 19.9 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001016744.1_53524001_2 - 0.0022 18.1 3.2 0.034 14.3 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.10 001016744.1_53524001_2 - 0.027 14.6 1.2 0.027 14.6 1.2 2.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.4 001016744.1_53524001_2 - 1.8 9.4 14.0 0.1 13.4 1.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Globin PF00042.20 001303297.1_36022001_1 - 2.4e-24 85.9 0.0 5.7e-24 84.7 0.0 1.6 2 0 0 2 2 2 1 Globin Ank_2 PF12796.5 001016356.2_53523001_2 - 2.3e-47 159.3 3.4 1.2e-15 57.7 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001016356.2_53523001_2 - 3e-46 155.1 6.9 8.2e-13 48.5 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.4 001016356.2_53523001_2 - 5.9e-42 140.9 10.2 2.3e-13 49.9 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.28 001016356.2_53523001_2 - 2.9e-39 131.7 1.7 1.3e-07 31.7 0.1 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.4 001016356.2_53523001_2 - 1e-37 123.7 0.5 1.2e-06 28.2 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat UDPGT PF00201.16 033480.1_16123120_1 - 8e-05 21.5 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.16 033480.1_16123120_2 - 6.7e-13 48.1 0.1 8.7e-13 47.7 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.16 033480.1_16123120_3 - 1.5e-08 33.8 0.0 1.8e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Sod_Fe_C PF02777.16 001281540.2_30923001_3 - 2.1e-38 130.4 0.0 3.5e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.20 001281540.2_30923001_3 - 2.8e-33 114.1 2.7 4.5e-33 113.4 2.7 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ODC_AZ PF02100.15 001289855.1_22523001_2 - 3.9e-21 75.1 0.0 9.1e-21 73.9 0.0 1.5 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289860.1_22323001_3 - 5.3e-21 74.6 0.0 9.7e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289872.1_22223001_3 - 5.3e-21 74.6 0.0 9.7e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289873.1_54023001_2 - 5.6e-21 74.5 0.0 8.9e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289876.1_44623001_1 - 6.8e-21 74.3 0.0 1.6e-20 73.1 0.0 1.5 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289889.1_27823001_2 - 7.1e-19 67.8 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290054.1_22523001_1 - 4.8e-21 74.8 0.0 1.7e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290057.1_30923001_3 - 1.5e-20 73.2 0.0 2.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290106.1_54023001_1 - 7.6e-21 74.1 0.0 2.1e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290115.1_44623001_2 - 1.1e-20 73.6 0.0 1.9e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290544.1_01522001_1 - 1e-14 54.4 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290739.1_11122001_2 - 8.8e-13 48.1 0.0 1.3e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001291895.1_02227001_1 - 3.3e-20 72.1 0.0 5.6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001291998.1_02222001_1 - 3.8e-13 49.3 0.0 5.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001289869.1_12023001_3 - 1.7e-21 76.2 0.0 2.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290064.2_12025001_3 - 5.2e-20 71.4 0.0 8.8e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001304716.1_27829001_2 - 2.1e-19 69.4 0.0 3.9e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001305094.1_45422001_1 - 1.4e-21 76.5 0.0 2.3e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001308082.1_42724001_2 - 4.4e-18 65.2 0.0 7.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001308099.1_42723001_3 - 7.3e-21 74.2 0.0 1.3e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001308113.1_42725001_3 - 4.9e-19 68.3 0.0 8e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Trypsin PF00089.24 001303337.1_27625001_2 - 3.9e-63 213.1 0.0 5.4e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.16 001303337.1_27625001_2 - 1.6e-43 146.8 6.3 9.7e-24 83.4 1.1 2.6 2 0 0 2 2 2 2 Kringle domain Thrombin_light PF09396.8 001303337.1_27625001_2 - 5.5e-24 83.6 0.6 1.2e-23 82.5 0.6 1.6 1 0 0 1 1 1 1 Thrombin light chain Gla PF00594.18 001303337.1_27625001_2 - 1.8e-20 72.7 7.4 3.7e-20 71.7 7.4 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1986 PF09342.9 001303337.1_27625001_2 - 6.9e-06 26.3 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001303337.1_27625001_2 - 0.073 13.8 0.0 0.16 12.7 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Gastrin PF00918.15 001303339.1_27622001_3 - 1.4e-35 122.8 0.0 2.1e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Gastrin/cholecystokinin family Hormone_recep PF00104.28 001303309.1_27625001_3 - 2.6e-31 108.7 0.3 4.2e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001303309.1_27625001_3 - 1e-30 105.8 12.3 2.1e-30 104.8 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PA28_beta PF02252.16 001303330.1_27623001_2 - 1.9e-52 176.6 1.2 3.1e-52 176.0 1.2 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.16 001303330.1_27623001_2 - 4.7e-24 84.2 0.6 9.7e-24 83.2 0.1 1.8 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit Phytoreo_P8 PF07124.9 001303330.1_27623001_2 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 PLA2_B PF01735.16 001303390.1_27626001_3 - 3e-140 467.8 0.0 3.7e-140 467.5 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.28 001303390.1_27626001_3 - 1.8e-14 53.7 0.0 4.2e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Sod_Cu PF00080.18 001303353.1_27622001_1 - 1.3e-28 99.9 0.2 2e-28 99.2 0.2 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DEAD PF00270.27 001303336.1_27625001_1 - 3.1e-49 167.0 0.0 6.4e-49 166.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001303336.1_27625001_1 - 2e-31 108.5 0.0 7.6e-31 106.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001303336.1_27625001_1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit p450 PF00067.20 001303344.1_27624001_1 - 5.8e-124 414.2 0.2 6.7e-124 414.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.29 001287276.1_01423001_1 - 9.2e-19 67.2 0.3 3.4e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain DUF1843 PF08898.8 001287276.1_01423001_1 - 0.093 13.1 1.7 0.42 11.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF4407 PF14362.4 001287276.1_01423001_1 - 0.2 10.8 6.7 0.28 10.3 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1266 PF06889.9 001287276.1_01423001_1 - 6.4 6.6 6.8 0.74 9.7 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1266) DnaJ_C PF01556.16 001287299.1_01423001_2 - 3.4e-43 147.1 0.4 4.6e-43 146.7 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 001287299.1_01423001_2 - 7.1e-27 93.2 2.3 1.4e-26 92.2 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.17 001287299.1_01423001_2 - 1.9e-15 56.8 20.8 4.9e-15 55.5 20.8 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.3 001287299.1_01423001_2 - 0.07 13.0 12.0 0.72 9.7 4.6 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.17 001287299.1_01423001_2 - 0.11 12.3 7.9 1.1 9.1 0.9 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cys_knot PF00007.20 001287317.1_01422001_2 - 3.9e-29 100.9 15.3 3.9e-29 100.9 15.3 1.6 2 0 0 2 2 2 1 Cystine-knot domain Toxin_11 PF07473.9 001287317.1_01422001_3 - 1.7 8.7 12.2 1.2 9.1 9.0 2.4 2 1 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species Cpn60_TCP1 PF00118.22 001287284.1_01425001_2 - 4.7e-86 289.2 15.3 1.2e-85 287.9 15.3 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSP20 PF00011.19 001287309.1_01422001_2 - 1.2e-24 86.2 0.0 1.8e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YabP PF07873.9 001287309.1_01422001_2 - 0.018 14.7 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 YabP family AMH_N PF04709.10 001287280.1_01425001_3 - 7.4e-121 403.6 9.3 9.6e-121 403.2 9.3 1.1 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region TGF_beta PF00019.18 001287280.1_01425001_3 - 3.3e-15 56.7 0.7 5.4e-15 56.0 0.7 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain Jun PF03957.11 001287608.1_01422001_2 - 7.1e-95 317.1 12.4 9.7e-95 316.7 12.4 1.2 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.19 001287608.1_01422001_2 - 9.2e-18 64.0 17.8 1.7e-17 63.1 17.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001287608.1_01422001_2 - 2.7e-09 36.8 14.4 6.1e-09 35.7 14.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001287608.1_01422001_2 - 8e-09 35.8 9.3 1.5e-08 34.9 9.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.10 001287608.1_01422001_2 - 0.00053 20.2 6.2 0.002 18.4 3.6 2.3 2 0 0 2 2 2 1 Cell division protein ZapB PspA_IM30 PF04012.10 001287608.1_01422001_2 - 0.0067 15.9 5.6 0.0067 15.9 5.6 1.4 1 1 0 1 1 1 1 PspA/IM30 family Fib_alpha PF08702.8 001287608.1_01422001_2 - 0.011 15.7 1.1 0.017 15.2 1.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.7 001287608.1_01422001_2 - 0.023 14.8 7.1 0.038 14.1 7.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.9 001287608.1_01422001_2 - 0.026 14.8 1.6 0.055 13.7 1.6 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TSC22 PF01166.16 001287608.1_01422001_2 - 0.058 13.6 1.0 0.18 12.0 1.0 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family Mnd1 PF03962.13 001287608.1_01422001_2 - 0.061 13.0 3.2 0.087 12.5 3.2 1.2 1 0 0 1 1 1 0 Mnd1 family DUF3450 PF11932.6 001287608.1_01422001_2 - 0.096 11.8 4.5 0.14 11.3 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.20 001287608.1_01422001_2 - 0.86 9.7 7.9 1.7 8.8 7.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.10 001287608.1_01422001_2 - 1.4 8.8 5.0 2.2 8.1 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.13 001287608.1_01422001_2 - 4.1 7.1 8.4 1.3 8.7 4.5 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF724 PF05266.12 001287608.1_01422001_2 - 5.6 6.6 8.8 9.4 5.9 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HSP90 PF00183.16 001287295.1_01426001_1 - 8e-99 331.7 3.5 1.6e-93 314.2 1.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.4 001287295.1_01426001_1 - 7.4e-11 41.9 0.0 2.7e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.24 001287295.1_01426001_1 - 5.1e-07 30.1 0.1 1e-06 29.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box PF00505.17 001287268.1_01423001_1 - 6.6e-26 90.4 1.3 1.8e-25 89.0 1.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.6 001287268.1_01423001_1 - 2e-25 89.5 0.3 2e-25 89.5 0.3 3.5 4 1 0 4 4 4 1 Sox developmental protein N terminal HMG_box_2 PF09011.8 001287268.1_01423001_1 - 8.6e-11 42.2 1.1 2.2e-10 40.8 1.1 1.8 1 0 0 1 1 1 1 HMG-box domain IBV_3B PF03622.11 001287268.1_01423001_1 - 0.13 12.3 0.3 0.31 11.1 0.3 1.5 1 0 0 1 1 1 0 IBV 3B protein OTCace PF00185.22 001287307.1_01424001_2 - 1.3e-50 171.4 0.0 2e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.19 001287307.1_01424001_2 - 2.9e-42 144.0 0.0 4.9e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Lipase_GDSL_2 PF13472.4 001287307.1_01424001_2 - 0.011 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CD225 PF04505.10 001310785.1_02121001_2 - 9.1e-19 67.2 1.1 1.2e-18 66.8 1.1 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein HORMA PF02301.16 045201.1_53527120_2 - 9.1e-08 31.8 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Arrestin_N PF00339.27 001104829.1_39124001_2 - 2.7e-39 134.4 0.2 1.9e-35 121.9 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 001104829.1_39124001_2 - 3.3e-22 79.2 0.1 6.1e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.5 001104829.1_39124001_2 - 0.014 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like Acetyltransf_1 PF00583.23 001104846.2_39122001_1 - 9.2e-12 45.1 0.0 1.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.5 001104846.2_39122001_1 - 1.5e-08 34.5 0.0 2.6e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 001104846.2_39122001_1 - 0.00042 20.6 0.0 0.00066 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-Mss51 PF13824.4 001104846.2_39122001_2 - 0.012 15.6 0.4 0.038 14.0 0.4 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 IL17 PF06083.9 001204788.1_39121001_2 - 9.7e-17 61.1 0.5 1.8e-16 60.2 0.5 1.4 1 0 0 1 1 1 1 Interleukin-17 MHC_I PF00129.16 001278878.2_39123001_1 - 1.5e-45 154.8 2.3 1.9e-45 154.5 2.3 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001278878.2_39123001_1 - 4.6e-11 42.9 0.0 1.3e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001278878.2_39123001_1 - 0.00035 21.0 0.0 0.00074 20.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001278878.2_39123001_1 - 0.00061 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain DUF973 PF06157.9 001278878.2_39123001_1 - 0.025 13.5 0.1 0.037 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Claudin_2 PF13903.4 001278878.2_39123001_1 - 0.044 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction AMA-1 PF02430.13 001278878.2_39123001_1 - 0.05 12.4 0.3 0.074 11.9 0.3 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 GSHPx PF00255.17 144456.1_53422120_1 - 8.9e-41 137.7 0.0 1.5e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 144456.1_53422120_1 - 4.9e-05 23.1 0.0 8.8e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family EF-hand_5 PF13202.4 144456.1_53422120_1 - 0.013 14.9 0.9 0.089 12.2 0.4 2.2 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.30 144456.1_53422120_1 - 0.4 10.2 1.8 1.2 8.7 0.7 2.1 2 0 0 2 2 2 0 EF hand GSHPx PF00255.17 144457.1_53422120_3 - 9.1e-41 137.7 0.0 1.2e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 144457.1_53422120_3 - 6.3e-05 22.7 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family EF-hand_5 PF13202.4 144457.1_53422120_3 - 0.012 15.0 0.9 0.078 12.4 0.4 2.1 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.30 144457.1_53422120_3 - 0.35 10.4 1.8 1.1 8.9 0.7 2.1 2 0 0 2 2 2 0 EF hand GSHPx PF00255.17 144460.1_53422120_1 - 7.1e-41 138.0 0.0 1e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 144460.1_53422120_1 - 0.00013 21.8 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family EF-hand_5 PF13202.4 144460.1_53422120_1 - 0.017 14.5 0.7 0.083 12.3 0.4 2.1 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.30 144460.1_53422120_1 - 0.27 10.7 1.8 1.1 8.8 0.7 2.3 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.30 001032461.1_12422001_3 - 1.6e-41 136.6 11.4 1.2e-09 36.9 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001032461.1_12422001_3 - 5e-35 119.7 2.8 1.2e-17 64.0 0.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001032461.1_12422001_3 - 6.9e-32 108.9 10.8 4.7e-15 55.0 0.6 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001032461.1_12422001_3 - 2.9e-30 101.5 6.0 2.4e-09 36.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001032461.1_12422001_3 - 8.2e-27 91.4 8.5 8e-07 28.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001032461.1_12422001_3 - 4.5e-15 55.6 0.2 6.7e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001032461.1_12422001_3 - 4.8e-09 36.0 0.4 0.0004 20.2 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001032461.1_12422001_3 - 3.1e-07 30.6 0.0 0.012 15.8 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001032461.1_12422001_3 - 6.1e-06 26.9 0.0 0.0013 19.4 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.11 001032461.1_12422001_3 - 0.0001 22.1 0.0 0.094 12.6 0.0 3.0 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.8 001032461.1_12422001_3 - 0.00032 20.6 0.5 0.0012 18.7 0.1 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.9 001032461.1_12422001_3 - 0.0037 16.8 1.5 0.0049 16.4 1.5 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.6 001032461.1_12422001_3 - 0.0046 17.6 0.3 1.8 9.2 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.4 001032461.1_12422001_3 - 0.01 16.2 0.0 3.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Caleosin PF05042.11 001032461.1_12422001_3 - 0.01 15.6 0.5 0.87 9.4 0.3 3.2 1 1 1 2 2 2 0 Caleosin related protein RNA_pol_Rpb4 PF03874.14 001032461.1_12422001_3 - 0.013 15.7 0.5 3.3 7.9 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb4 TerB PF05099.11 001032461.1_12422001_3 - 0.014 15.3 0.4 1.9 8.3 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB MotA_activ PF09114.8 001032461.1_12422001_3 - 0.032 14.2 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain GPHH PF16905.3 001032461.1_12422001_3 - 0.034 13.8 0.0 0.37 10.5 0.0 2.7 4 0 0 4 4 4 0 Voltage-dependent L-type calcium channel, IQ-associated SurA_N_2 PF13623.4 001032461.1_12422001_3 - 0.063 13.0 0.6 1.7 8.3 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain Poly_export PF02563.14 001032461.1_12422001_3 - 0.068 13.3 0.0 2.3 8.3 0.0 2.9 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein DUF2267 PF10025.7 001032461.1_12422001_3 - 0.13 12.4 0.0 0.45 10.7 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Cadherin PF00028.15 001172196.1_53427001_3 - 1.3e-74 246.5 4.5 1.2e-14 54.4 0.0 6.5 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.10 001172196.1_53427001_3 - 0.022 14.4 0.1 0.39 10.4 0.0 3.0 4 0 0 4 4 4 0 Cadherin-like LAX PF15681.3 001172196.1_53427001_3 - 0.046 12.3 0.3 0.082 11.5 0.1 1.4 2 0 0 2 2 2 0 Lymphocyte activation family X GAPT PF11770.6 001172196.1_53427001_3 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) SCAB-IgPH PF16709.3 001172196.1_53427001_3 - 0.1 12.1 0.2 3.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Fused Ig-PH domain of plant-specific actin-binding protein Ras PF00071.20 001310354.1_02122001_1 - 1e-58 197.4 0.5 1.3e-58 197.0 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001310354.1_02122001_1 - 7.2e-36 122.9 0.2 1.2e-35 122.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001310354.1_02122001_1 - 3.2e-15 55.9 0.2 4e-15 55.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001310354.1_02122001_1 - 2.3e-06 27.1 0.1 1.1e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001310354.1_02122001_1 - 7.3e-06 25.4 0.1 1.3e-05 24.6 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001310354.1_02122001_1 - 4.7e-05 23.3 0.0 8.4e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001310354.1_02122001_1 - 0.00022 21.0 0.1 0.093 12.5 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001310354.1_02122001_1 - 0.00028 20.2 0.3 0.00038 19.8 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.16 001310354.1_02122001_1 - 0.00029 20.3 0.3 0.006 16.0 0.2 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B CD225 PF04505.10 001310795.1_02122001_1 - 2.9e-20 72.0 0.6 2.9e-20 72.0 0.6 1.6 2 0 0 2 2 2 1 Interferon-induced transmembrane protein TMEM237 PF15383.4 001310795.1_02122001_1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 Elongin_A PF06881.9 001310361.1_02123001_1 - 0.00058 20.2 1.2 0.0014 18.9 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.5 001310361.1_02123001_1 - 0.0027 17.4 0.3 0.0093 15.7 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001310361.1_02123001_1 - 0.081 12.7 0.6 0.35 10.7 0.2 2.4 2 0 0 2 2 2 0 F-box domain zf-C4 PF00105.16 001310383.1_02123001_3 - 1.3e-28 99.1 15.9 2.4e-28 98.3 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001310383.1_02123001_3 - 1.1e-14 54.4 0.1 2.7e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Tautomerase PF01361.19 001310383.1_02123001_3 - 0.13 12.1 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Tautomerase enzyme zf-BED PF02892.13 001310383.1_02123001_3 - 9.6 6.2 13.2 34 4.5 0.0 3.4 3 0 0 3 3 3 0 BED zinc finger Biliv-reduc_cat PF09166.8 001310378.1_02123001_3 - 8.2e-59 196.7 0.0 1.3e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Biliverdin reductase, catalytic GFO_IDH_MocA PF01408.20 001310378.1_02123001_3 - 7.6e-17 62.1 0.2 1.6e-16 61.1 0.2 1.6 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF2737 PF10930.6 001310378.1_02123001_3 - 0.058 12.8 0.0 0.17 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) PAX PF00292.16 001310395.1_02124001_1 - 6e-73 242.6 0.7 9.3e-73 241.9 0.7 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.27 001310395.1_02124001_1 - 1.4e-23 82.4 6.8 2.7e-23 81.4 6.8 1.5 1 0 0 1 1 1 1 Homeobox domain Pax7 PF12360.6 001310395.1_02124001_1 - 7.5e-20 70.7 6.7 1.7e-19 69.6 6.7 1.7 1 0 0 1 1 1 1 Paired box protein 7 Homeobox_KN PF05920.9 001310395.1_02124001_1 - 5.6e-05 22.8 1.6 9.3e-05 22.1 0.8 1.8 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.4 001310395.1_02124001_1 - 7e-05 22.4 2.1 0.0025 17.4 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.4 001310395.1_02124001_1 - 0.0016 18.9 6.0 0.071 13.6 0.0 3.4 2 2 1 3 3 3 2 Homeodomain-like domain HTH_Tnp_IS1 PF12759.5 001310395.1_02124001_1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 InsA C-terminal domain TGFb_propeptide PF00688.16 001310789.1_02123001_1 - 1.4e-53 182.1 0.9 1.9e-53 181.6 0.9 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 001310789.1_02123001_1 - 8.1e-34 116.5 0.5 1.7e-33 115.5 0.5 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Tnp_DNA_bind PF14706.4 001310789.1_02123001_1 - 0.076 12.7 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Transposase DNA-binding LRR_8 PF13855.4 001310782.1_02126001_1 - 9.6e-80 262.2 99.4 2.2e-12 46.4 0.6 11.8 5 4 8 13 13 13 13 Leucine rich repeat LRR_4 PF12799.5 001310782.1_02126001_1 - 2.8e-29 100.4 112.0 1.9e-05 24.8 0.7 13.4 6 3 9 16 16 16 15 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001310782.1_02126001_1 - 3.4e-26 91.6 30.3 2e-10 40.6 6.7 5.9 2 1 5 7 7 7 7 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001310782.1_02126001_1 - 2e-13 50.1 40.9 4.5e-05 22.9 0.7 7.1 1 1 5 7 7 7 5 Leucine-rich repeat TIR PF01582.18 001310782.1_02126001_1 - 4.9e-13 49.1 2.8 8.5e-13 48.3 2.8 1.4 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001310782.1_02126001_1 - 5.9e-08 32.0 89.8 0.59 10.7 0.3 19.5 19 2 0 19 19 19 5 Leucine Rich Repeat TIR_2 PF13676.4 001310782.1_02126001_1 - 1.3e-06 28.6 0.3 4.6e-06 26.8 0.2 1.9 2 0 0 2 2 2 1 TIR domain LRRNT PF01462.16 001310782.1_02126001_1 - 0.0056 16.2 0.2 0.0056 16.2 0.2 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain cEGF PF12662.5 001310421.1_02124001_2 - 0.053 13.3 0.5 0.11 12.3 0.5 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like Actin PF00022.17 001310421.1_02124001_3 - 4.4e-150 499.7 0.0 1.1e-149 498.3 0.0 1.6 1 1 0 1 1 1 1 Actin ARD PF03079.12 001285955.1_02125001_2 - 2.3e-48 164.2 0.2 3.2e-48 163.7 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.9 001285955.1_02125001_2 - 1.3e-07 31.1 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.17 001285955.1_02125001_2 - 0.00026 20.8 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.20 001285955.1_02125001_2 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Cupin RFC1 PF08519.10 001310384.1_02128001_1 - 1.5e-60 203.7 0.0 3.7e-60 202.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.24 001310384.1_02128001_1 - 4.7e-18 65.2 0.0 2e-17 63.2 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.27 001310384.1_02128001_1 - 1.4e-15 57.8 0.0 3e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.5 001310384.1_02128001_1 - 4.5e-07 29.6 0.0 1.5e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 twin BRCT domain AAA_22 PF13401.4 001310384.1_02128001_1 - 0.00015 22.0 0.0 0.00056 20.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.4 001310384.1_02128001_1 - 0.00024 21.0 0.0 0.00079 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.12 001310384.1_02128001_1 - 0.00029 20.7 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.20 001310384.1_02128001_1 - 0.00046 20.4 0.1 0.007 16.6 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_33 PF13671.4 001310384.1_02128001_1 - 0.0018 18.3 0.0 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.10 001310384.1_02128001_1 - 0.002 17.3 0.0 0.0048 16.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.4 001310384.1_02128001_1 - 0.0021 18.3 0.0 0.0055 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.11 001310384.1_02128001_1 - 0.0025 16.7 0.0 0.0055 15.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_30 PF13604.4 001310384.1_02128001_1 - 0.0036 16.9 0.0 0.0091 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain BRCT_2 PF16589.3 001310384.1_02128001_1 - 0.0062 16.8 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain AAA_17 PF13207.4 001310384.1_02128001_1 - 0.0072 16.6 0.0 0.039 14.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.10 001310384.1_02128001_1 - 0.0075 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.4 001310384.1_02128001_1 - 0.0076 16.6 0.6 0.034 14.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.13 001310384.1_02128001_1 - 0.065 13.0 0.2 0.21 11.4 0.1 1.9 1 1 1 2 2 2 0 NTPase AAA_assoc_2 PF16193.3 001310384.1_02128001_1 - 0.094 12.9 0.0 7.4 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA C-terminal domain MHC_II_alpha PF00993.18 001310349.1_02122001_1 - 1.2e-33 114.5 0.3 1.7e-33 114.0 0.3 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001310349.1_02122001_1 - 9.5e-28 95.2 0.6 2.1e-27 94.1 0.6 1.6 1 0 0 1 1 1 1 C1-set C-terminal domain C1-set PF07654.13 001310349.1_02122001_1 - 8.5e-25 86.9 0.0 1.7e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001310349.1_02122001_1 - 0.00045 20.7 0.0 0.00077 19.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001310349.1_02122001_1 - 0.0033 17.3 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Oest_recep PF02159.13 001282825.1_13324001_2 - 2.5e-67 225.5 8.1 2.5e-67 225.5 8.1 2.0 2 0 0 2 2 2 1 Oestrogen receptor Hormone_recep PF00104.28 001282825.1_13324001_2 - 2.1e-34 118.8 3.8 2.1e-34 118.8 3.8 1.5 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001282825.1_13324001_2 - 1.4e-31 108.6 13.9 2.5e-31 107.8 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ESR1_C PF12743.5 001282825.1_13324001_2 - 6.2e-19 67.4 4.4 6.2e-19 67.4 4.4 2.1 2 0 0 2 2 2 1 Oestrogen-type nuclear receptor final C-terminal Thyroglob_assoc PF16597.3 001282825.1_13324001_2 - 0.1 12.7 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain Tyrosinase PF00264.18 001315525.1_13324001_1 - 2.4e-33 116.2 0.1 6.6e-33 114.7 0.1 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Laminin_EGF PF00053.22 001315525.1_13324001_1 - 0.65 10.0 13.4 0.95 9.5 9.8 2.7 2 1 0 2 2 2 0 Laminin EGF domain IFN-gamma PF00714.15 001282845.1_13321001_1 - 4.4e-28 97.7 0.9 5.4e-28 97.4 0.9 1.1 1 0 0 1 1 1 1 Interferon gamma API5 PF05918.9 001282845.1_13321001_1 - 0.0071 15.1 0.7 0.0087 14.8 0.7 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Fib_alpha PF08702.8 001282845.1_13321001_1 - 0.026 14.6 4.9 0.041 13.9 0.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.12 001282845.1_13321001_1 - 0.067 12.9 3.1 0.11 12.1 3.1 1.5 1 1 0 1 1 1 0 IncA protein LPP PF04728.11 001282845.1_13321001_1 - 0.19 12.0 2.0 0.38 11.0 0.1 2.3 2 1 0 2 2 2 0 Lipoprotein leucine-zipper IL1 PF00340.17 001282824.1_13322001_1 - 3.9e-21 74.8 0.0 6.5e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Interleukin-1 / 18 IL1_propep PF02394.14 001282824.1_13322001_1 - 1.9e-06 28.6 0.0 3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Interleukin-1 propeptide FYVE_2 PF02318.14 001282836.1_13325001_1 - 9.2e-50 167.7 12.4 9.2e-50 167.7 12.4 2.7 3 0 0 3 3 3 1 FYVE-type zinc finger Rab_eff_C PF04698.10 001282836.1_13325001_1 - 3e-41 141.4 20.1 6.7e-41 140.3 19.9 1.4 1 1 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus SecA_DEAD PF07517.12 001282836.1_13325001_1 - 0.062 12.5 0.8 0.47 9.6 0.1 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain DUF1664 PF07889.10 001282836.1_13325001_1 - 0.071 13.0 0.2 0.071 13.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Phage_tail_NK PF16532.3 001282836.1_13325001_1 - 0.13 11.8 0.1 0.37 10.2 0.1 1.8 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales PEGA PF08308.9 001282836.1_13325001_1 - 0.16 11.8 0.4 0.31 10.8 0.4 1.5 1 0 0 1 1 1 0 PEGA domain NPV_P10 PF05531.10 001282836.1_13325001_1 - 0.18 12.2 3.2 12 6.3 0.5 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.12 001282836.1_13325001_1 - 2.1 8.0 27.7 0.34 10.5 3.0 2.8 3 0 0 3 3 3 0 IncA protein BLOC1_2 PF10046.7 001282836.1_13325001_1 - 2.4 8.4 10.1 1.2 9.4 1.1 3.2 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.14 001282836.1_13325001_1 - 3.6 8.0 13.1 0.15 12.4 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function DUF16 DUF4094 PF13334.4 001282836.1_13325001_1 - 4.9 7.5 8.8 1.9 8.8 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) 7tm_1 PF00001.19 001282818.1_13324001_1 - 1.6e-81 273.4 0.1 2.6e-81 272.7 0.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001282818.1_13324001_1 - 5.4e-09 35.7 5.1 5.4e-09 35.7 5.1 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001282818.1_13324001_1 - 7e-07 28.7 6.1 7e-07 28.7 6.1 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001282818.1_13324001_1 - 1.6e-05 24.6 13.3 1.7e-05 24.6 2.7 2.4 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srbc PF10316.7 001282818.1_13324001_1 - 0.00011 21.7 8.5 0.00011 21.7 8.5 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc KCNQ_channel PF03520.12 001282826.1_13326001_1 - 4.2e-82 274.5 0.2 6.4e-82 273.9 0.2 1.3 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.6 001282826.1_13326001_1 - 1e-39 134.8 1.7 2.1e-39 133.8 1.7 1.6 1 0 0 1 1 1 1 Ankyrin-G binding motif of KCNQ2-3 Ion_trans PF00520.29 001282826.1_13326001_1 - 3.9e-29 101.4 2.9 3.9e-29 101.4 2.9 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.14 001282826.1_13326001_1 - 2.4e-12 46.5 0.5 2.4e-12 46.5 0.5 1.9 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.24 001282826.1_13326001_1 - 0.00031 20.5 0.0 0.00079 19.2 0.0 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.26 001315526.1_13327001_1 - 2.6e-81 273.3 0.0 3.6e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001315526.1_13327001_1 - 1.5e-53 180.6 0.1 2.3e-53 179.9 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001315526.1_13327001_1 - 8.5e-47 158.0 0.0 4.9e-46 155.5 0.0 2.3 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001315526.1_13327001_1 - 1.4e-17 63.8 0.0 2.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.4 001315526.1_13327001_1 - 4.2e-09 36.4 0.0 7.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein AhpC-TSA PF00578.19 001282840.1_13322001_2 - 1.2e-29 102.7 0.0 1.5e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.7 001282840.1_13322001_2 - 9.3e-13 47.7 0.3 1.6e-12 46.9 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.8 001282840.1_13322001_2 - 1.3e-12 47.5 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.4 001282840.1_13322001_2 - 0.039 14.0 0.0 0.07 13.2 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme PPARgamma_N PF12577.6 001282827.1_13324001_1 - 1.7e-34 118.2 1.6 3.9e-34 117.0 1.6 1.7 1 0 0 1 1 1 1 PPAR gamma N-terminal region zf-C4 PF00105.16 001282827.1_13324001_1 - 2.1e-27 95.3 15.2 3.8e-27 94.4 15.2 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001282827.1_13324001_1 - 5.5e-17 61.9 0.2 1.4e-16 60.6 0.2 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Tmemb_55A PF09788.7 001282827.1_13324001_1 - 0.039 12.9 3.1 0.064 12.2 3.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A Orn_Arg_deC_N PF02784.14 001293753.1_13323001_3 - 4.7e-60 203.0 0.0 5.8e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293753.1_13323001_3 - 5.4e-14 52.1 0.0 1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293753.1_13323001_3 - 1.8e-05 24.2 0.0 9.6e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel NMDAR2_C PF10565.7 001315519.1_13329001_1 - 2.2e-272 905.7 34.5 2.6e-272 905.5 34.5 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.24 001315519.1_13329001_1 - 1.1e-34 119.3 0.1 1.1e-34 119.3 0.1 2.7 3 0 0 3 3 3 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001315519.1_13329001_1 - 3.4e-30 104.4 0.1 1.5e-29 102.3 0.1 2.0 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001315519.1_13329001_1 - 4.2e-21 75.3 0.0 1.3e-20 73.7 0.0 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.26 001315519.1_13329001_1 - 3.6e-10 39.4 1.7 1.4e-09 37.4 1.7 1.9 1 1 0 1 1 1 1 Receptor family ligand binding region Cript PF10235.7 001315519.1_13329001_1 - 0.33 11.4 5.1 0.15 12.5 0.4 2.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-C4 PF00105.16 001315520.1_13324001_2 - 4.9e-33 113.3 12.9 4.9e-33 113.3 12.9 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001315520.1_13324001_2 - 6.1e-24 84.6 4.6 6.1e-24 84.6 4.6 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001282834.1_13324001_3 - 1.5e-28 98.9 16.1 3.2e-28 97.9 16.1 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001282834.1_13324001_3 - 9e-16 57.9 0.1 1.8e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor IRK PF01007.18 001290101.1_13325001_1 - 1.3e-156 520.5 1.9 1.8e-156 520.1 1.9 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK_N PF08466.8 001290101.1_13325001_1 - 3.1e-26 91.1 1.3 7.5e-26 89.9 1.3 1.7 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.14 001290101.1_13325001_1 - 0.001 18.9 4.6 0.001 18.9 4.6 1.8 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.29 001290101.1_13325001_1 - 0.0036 16.4 4.5 0.0062 15.7 4.5 1.4 1 0 0 1 1 1 1 Ion transport protein Syndecan PF01034.18 001282832.1_13322001_3 - 1.8e-24 85.3 0.2 2.8e-24 84.7 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.9 001282832.1_13322001_3 - 0.026 14.3 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Gastrin PF00918.15 001303434.1_13321001_1 - 5.5e-51 172.6 0.0 6.2e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Gastrin/cholecystokinin family AAA PF00004.27 001293052.1_13323001_1 - 4.4e-43 146.8 0.0 1.1e-42 145.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293052.1_13323001_1 - 2e-07 31.2 0.0 5.1e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293052.1_13323001_1 - 2.5e-06 27.4 0.0 1.5e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293052.1_13323001_1 - 3.4e-06 27.4 0.2 7.2e-05 23.1 0.0 2.7 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293052.1_13323001_1 - 3.7e-05 23.9 1.3 0.005 17.0 0.2 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293052.1_13323001_1 - 8.6e-05 21.8 0.0 0.00017 20.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293052.1_13323001_1 - 0.0014 17.5 0.0 0.0029 16.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293052.1_13323001_1 - 0.0017 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293052.1_13323001_1 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293052.1_13323001_1 - 0.0023 18.3 0.2 0.019 15.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.9 001293052.1_13323001_1 - 0.0058 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.19 001293052.1_13323001_1 - 0.0059 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.11 001293052.1_13323001_1 - 0.0079 15.4 0.0 0.023 13.9 0.0 1.7 1 0 0 1 1 1 1 KaiC PhoH PF02562.14 001293052.1_13323001_1 - 0.0086 15.4 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.4 001293052.1_13323001_1 - 0.018 15.2 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293052.1_13323001_1 - 0.018 15.1 3.4 0.049 13.7 3.4 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293052.1_13323001_1 - 0.021 14.4 0.1 0.096 12.3 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293052.1_13323001_1 - 0.025 14.2 0.1 0.061 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.15 001293052.1_13323001_1 - 0.04 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293052.1_13323001_1 - 0.045 12.7 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.11 001293052.1_13323001_1 - 0.048 12.7 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.4 001293052.1_13323001_1 - 0.048 13.1 0.0 0.16 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.4 001293052.1_13323001_1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001293052.1_13323001_1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.4 001293052.1_13323001_1 - 0.068 13.5 0.6 0.45 10.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.4 001293052.1_13323001_1 - 0.073 12.6 0.7 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.10 001293052.1_13323001_1 - 0.11 11.6 0.2 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.4 001293052.1_13323001_1 - 0.12 12.5 0.2 0.49 10.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain SlyX PF04102.10 001293052.1_13323001_1 - 0.15 12.6 2.4 0.51 10.9 2.4 2.0 1 0 0 1 1 1 0 SlyX Laminin_II PF06009.10 001293052.1_13323001_1 - 0.17 11.8 3.6 1.1 9.1 1.0 2.7 3 0 0 3 3 3 0 Laminin Domain II DivIC PF04977.13 001293052.1_13323001_1 - 0.24 11.1 3.0 0.58 9.8 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator MscS_porin PF12795.5 001293052.1_13323001_1 - 6.6 6.1 12.7 11 5.4 12.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Abhydrolase_1 PF00561.18 103454.1_23527120_3 - 1.9e-14 53.8 0.0 2.6e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 103454.1_23527120_3 - 4e-10 40.6 0.3 6.9e-10 39.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 103454.1_23527120_3 - 5.7e-08 32.2 0.0 8.3e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 GnRH PF00446.15 001286338.1_25021001_2 - 0.00018 21.4 7.6 0.00034 20.6 7.6 1.5 1 0 0 1 1 1 1 Gonadotropin-releasing hormone zf-C4 PF00105.16 001309944.1_23124001_1 - 8.5e-31 106.1 11.7 1.7e-30 105.1 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001309944.1_23124001_1 - 6.4e-30 104.1 0.2 9.1e-30 103.7 0.2 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001309942.1_23125001_1 - 9.6e-27 93.1 14.8 2.7e-26 91.7 14.8 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001309942.1_23125001_1 - 9.3e-17 61.2 0.8 3.2e-16 59.4 0.8 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ATP-synt_ab PF00006.23 001309933.1_23126001_3 - 8.5e-109 362.0 0.0 1.2e-108 361.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.3 001309933.1_23126001_3 - 5.1e-44 148.9 0.0 9e-44 148.1 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.21 001309933.1_23126001_3 - 5.4e-14 52.3 2.4 1.6e-13 50.9 2.4 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-gua_Ptrans PF00217.17 001309976.1_23123001_1 - 3.7e-98 327.9 0.0 5e-98 327.4 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.13 001309976.1_23123001_1 - 1.5e-30 105.3 0.0 2.9e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain ANP PF00212.16 001309965.1_23122001_2 - 5.2e-10 39.2 4.3 1.3e-09 37.9 4.3 1.7 1 0 0 1 1 1 1 Atrial natriuretic peptide ANP PF00212.16 001309966.1_23122001_1 - 4.8e-12 45.7 7.1 8.3e-12 44.9 7.1 1.4 1 0 0 1 1 1 1 Atrial natriuretic peptide DUF4661 PF15576.4 001309966.1_23122001_1 - 0.05 13.4 0.5 0.073 12.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) 7tm_1 PF00001.19 001310010.1_23124001_1 - 2.7e-49 167.7 17.6 4.4e-49 167.0 17.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MIP PF00230.18 001310008.1_23122001_2 - 4.2e-77 258.8 16.0 5e-77 258.5 16.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein TMEM237 PF15383.4 001310008.1_23122001_2 - 0.2 10.6 0.6 0.29 10.0 0.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 p450 PF00067.20 001309992.1_23124001_3 - 2.8e-88 296.5 0.0 3.4e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Runt PF00853.17 001309972.1_23123001_1 - 8.7e-73 241.9 0.1 1.3e-72 241.3 0.1 1.3 1 0 0 1 1 1 1 Runt domain RunxI PF08504.9 001309972.1_23123001_1 - 2.2e-36 124.4 4.7 2.2e-36 124.4 4.7 2.0 2 0 0 2 2 2 1 Runx inhibition domain Zona_pellucida PF00100.21 001309997.1_23125001_2 - 3.5e-49 167.7 0.0 4.7e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.16 001309997.1_23125001_2 - 3.8e-06 26.5 6.7 3.8e-06 26.5 6.7 2.7 3 0 0 3 3 3 1 Trefoil (P-type) domain DUF4573 PF15140.4 001309997.1_23125001_3 - 7.9e-11 41.9 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) DUF4868 PF16162.3 001309997.1_23125001_3 - 0.58 9.9 4.9 0.84 9.4 2.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4868) BCDHK_Adom3 PF10436.7 001309964.2_23123001_2 - 3.6e-50 169.8 0.0 5.3e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.24 001309964.2_23123001_2 - 1.8e-13 50.9 0.0 2.7e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Calici_PP_N PF08405.9 001309964.2_23123001_2 - 0.022 13.5 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal HATPase_c_3 PF13589.4 001309964.2_23123001_2 - 0.048 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.10 001309914.1_23127001_3 - 9.3e-29 99.4 0.0 3.8e-22 78.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001309914.1_23127001_3 - 2.4e-24 85.5 0.2 5.3e-21 74.7 0.0 2.4 2 0 0 2 2 2 2 PAS domain HIF-1a_CTAD PF08778.8 001309914.1_23127001_3 - 4.3e-19 67.7 5.3 1.7e-18 65.8 5.8 1.8 2 0 0 2 2 2 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.6 001309914.1_23127001_3 - 2.1e-17 62.1 3.5 3.7e-17 61.3 3.5 1.4 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 PAS PF00989.23 001309914.1_23127001_3 - 1.9e-16 59.9 0.0 1.2e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.5 001309914.1_23127001_3 - 2e-12 47.1 0.1 1.2e-06 28.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001309914.1_23127001_3 - 3.6e-07 30.3 0.0 0.038 14.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.24 001309914.1_23127001_3 - 0.02 14.7 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Homeobox PF00046.27 001309978.1_23123001_1 - 9.1e-22 76.5 4.2 1.8e-21 75.6 4.2 1.5 1 0 0 1 1 1 1 Homeobox domain Vps36-NZF-N PF16988.3 001309978.1_23123001_2 - 0.082 12.2 2.4 0.33 10.3 0.1 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain E1-E2_ATPase PF00122.18 001309999.1_23127001_2 - 4.7e-56 189.4 3.8 4.7e-56 189.4 3.8 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.19 001309999.1_23127001_2 - 3.3e-44 150.6 0.2 3.3e-44 150.6 0.2 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.4 001309999.1_23127001_2 - 3.1e-22 78.3 0.0 7.1e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.24 001309999.1_23127001_2 - 3.8e-19 69.7 0.0 5e-10 39.9 0.0 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 001309999.1_23127001_2 - 1.5e-16 59.7 0.0 3e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.10 001309999.1_23127001_2 - 9.6e-06 25.4 1.1 0.00088 18.9 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.14 001309999.1_23127001_2 - 0.013 14.9 0.1 1.1 8.7 0.0 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 Phage_holin_3_6 PF07332.9 001309999.1_23127001_2 - 3.6 7.5 7.3 9.1 6.2 2.8 2.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III An_peroxidase PF03098.13 001309923.1_23125001_1 - 1.2e-50 172.4 0.0 2.1e-44 151.9 0.0 2.3 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.25 001309923.1_23125001_1 - 0.65 10.2 12.3 1.1 9.5 10.9 2.1 2 0 0 2 2 2 0 EGF-like domain Zona_pellucida PF00100.21 001309917.1_23123001_3 - 3.8e-41 141.4 0.4 4.9e-41 141.0 0.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain UQ_con PF00179.24 001309940.1_23122001_1 - 2.5e-53 179.3 0.0 3.2e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001309940.1_23122001_1 - 0.001 19.2 0.1 0.0016 18.6 0.1 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.11 001309940.1_23122001_1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain p450 PF00067.20 001309970.1_23124001_1 - 1e-79 268.3 0.0 1.2e-79 268.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF349 PF03993.10 001309970.1_23124001_1 - 1.2 9.3 4.9 0.75 10.0 1.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) TMEM154 PF15102.4 001309970.1_23124001_1 - 1.9 8.3 6.6 0.52 10.1 1.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family p450 PF00067.20 001309918.1_23124001_1 - 8.2e-105 351.1 0.0 9.5e-105 350.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2232 PF09991.7 001309918.1_23124001_1 - 0.17 10.9 0.3 0.31 10.1 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Hormone_recep PF00104.28 001309977.2_23125001_2 - 1.4e-37 129.2 4.0 2.2e-37 128.6 4.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001309977.2_23125001_2 - 1.7e-31 108.4 13.0 3.5e-31 107.3 13.0 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ERbeta_N PF12497.6 001309977.2_23125001_2 - 8.6e-28 96.3 12.1 2e-27 95.1 12.1 1.6 1 0 0 1 1 1 1 Estrogen receptor beta ANTH PF07651.14 001309977.2_23125001_2 - 0.0056 15.6 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain zf-C4 PF00105.16 001279560.2_37527001_1 - 5.9e-32 109.8 12.3 1.7e-31 108.3 12.3 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001279560.2_37527001_1 - 1.5e-30 106.2 3.6 2.3e-30 105.6 3.6 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Cys_knot PF00007.20 001309987.1_23121001_1 - 1.4e-22 79.9 16.1 1.6e-22 79.6 16.1 1.1 1 0 0 1 1 1 1 Cystine-knot domain 7tm_1 PF00001.19 001323590.1_40823001_3 - 1e-69 234.6 4.4 1.2e-69 234.4 4.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001323590.1_40823001_3 - 8.3e-13 48.2 8.1 2.1e-06 27.2 7.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001323590.1_40823001_3 - 1.6e-06 28.0 9.1 1e-05 25.3 3.0 2.1 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001323590.1_40823001_3 - 0.0024 17.1 10.5 0.0032 16.7 7.2 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4635 PF15466.4 001323590.1_40823001_3 - 0.095 12.1 0.2 7.1 6.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Ependymin PF00811.16 001309838.1_12822001_3 - 7.3e-30 103.7 0.2 9.7e-30 103.3 0.2 1.2 1 0 0 1 1 1 1 Ependymin 7tm_1 PF00001.19 001311081.1_30923001_1 - 2.9e-42 144.6 16.2 3.5e-42 144.4 16.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001311081.1_30923001_1 - 3.7e-07 29.7 15.6 6.7e-07 28.8 15.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001311081.1_30923001_1 - 3.6e-06 26.8 11.8 0.00013 21.7 2.3 2.0 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001311081.1_30923001_1 - 0.00046 19.5 17.4 0.00096 18.4 17.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1673 PF07895.9 001311081.1_30923001_1 - 0.02 14.5 7.8 0.47 10.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Peptidase_M56 PF05569.9 001311081.1_30923001_1 - 0.26 10.3 1.6 0.62 9.1 0.2 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 Ribosomal_L26 PF16906.3 001310981.2_21522001_1 - 1.9e-44 149.9 6.3 2.7e-44 149.4 6.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.27 001310981.2_21522001_1 - 1.1e-07 31.4 5.8 3e-07 30.0 5.8 1.9 1 1 0 1 1 1 1 KOW motif eIF3_subunit PF08597.8 077062.2_53526120_2 - 9.8e-48 163.0 7.3 1.4e-47 162.6 7.3 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit zf-rbx1 PF12678.5 077062.2_53526120_2 - 0.34 11.1 5.1 1.3 9.3 5.1 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain eIF3_subunit PF08597.8 077062.2_53526120_3 - 0.012 15.5 5.3 0.016 15.0 5.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit BTD PF09270.8 001278692.1_30524001_3 - 2.6e-73 245.2 0.0 4.2e-73 244.5 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.9 001278692.1_30524001_3 - 1.8e-49 168.2 0.7 4.3e-49 166.9 0.7 1.7 1 0 0 1 1 1 1 LAG1, DNA binding ER_lumen_recept PF00810.16 001011046.1_53523001_2 - 3.5e-56 190.0 10.0 3.5e-56 190.0 10.0 1.9 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.12 001011046.1_53523001_2 - 1.9 8.2 15.9 1.5 8.5 1.0 4.0 3 1 1 4 4 4 0 PQ loop repeat zf-C2H2 PF00096.24 001002314.1_16126001_1 - 1.4e-24 85.0 24.6 1.4e-05 25.1 1.6 6.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type BTB PF00651.29 001002314.1_16126001_1 - 1.4e-23 83.1 0.0 2.4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.4 001002314.1_16126001_1 - 8.6e-19 66.9 30.4 2.8e-07 30.6 0.1 7.5 8 0 0 8 8 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 001002314.1_16126001_1 - 5.5e-18 64.0 35.3 0.00027 21.4 0.7 6.4 6 0 0 6 6 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001002314.1_16126001_1 - 1.5e-14 53.7 5.4 0.00088 19.4 0.2 5.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001002314.1_16126001_1 - 1.5e-10 40.6 20.0 0.0088 15.8 0.3 6.0 5 1 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.5 001002314.1_16126001_1 - 4.1e-10 39.6 16.8 0.0088 16.3 0.7 6.0 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 001002314.1_16126001_1 - 0.0071 15.9 16.8 0.49 10.1 0.6 4.3 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-Di19 PF05605.10 001002314.1_16126001_1 - 0.01 16.0 14.1 0.14 12.3 0.6 4.0 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.8 001002314.1_16126001_1 - 0.058 13.4 10.9 0.24 11.4 1.3 3.5 2 1 1 3 3 3 0 Zinc ribbon domain Pox_VERT_large PF04441.11 001002314.1_16126001_1 - 0.073 11.2 0.1 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit zf-C2H2_2 PF12756.5 001002314.1_16126001_1 - 0.076 13.2 24.5 2.7 8.2 8.0 5.8 3 1 2 5 5 4 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.20 001002314.1_16126001_1 - 0.18 11.6 2.7 0.94 9.3 0.1 3.0 2 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_9 PF16293.3 001002314.1_16126001_1 - 0.22 11.3 3.1 18 5.1 0.0 3.9 3 1 1 4 4 3 0 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.4 001002314.1_16126001_1 - 0.41 10.3 24.5 8.2 6.1 0.5 5.5 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-AN1 PF01428.14 001002314.1_16126001_1 - 0.47 10.5 9.3 39 4.4 0.2 4.6 4 0 0 4 4 4 0 AN1-like Zinc finger DZR PF12773.5 001002314.1_16126001_1 - 1.6 8.7 7.3 3.7e+02 1.1 7.1 3.0 1 1 0 1 1 1 0 Double zinc ribbon LIM PF00412.20 001002314.1_16126001_1 - 2 8.6 10.5 0.23 11.6 0.2 3.4 2 1 2 4 4 4 0 LIM domain zinc_ribbon_15 PF17032.3 001002314.1_16126001_1 - 4.2 8.0 7.9 14 6.4 0.4 3.3 2 1 0 3 3 3 0 zinc-ribbon family zf-HYPF PF07503.10 001002314.1_16126001_1 - 7.4 6.3 6.7 15 5.3 0.4 3.3 3 1 0 3 3 3 0 HypF finger SGT1 PF07093.9 001078270.1_12426001_2 - 1e-180 601.9 1.6 1.3e-180 601.6 1.6 1.0 1 0 0 1 1 1 1 SGT1 protein zf-H2C2_2 PF13465.4 001078387.1_12425001_2 - 1.8e-20 72.2 78.2 2.8e-06 27.4 5.1 10.0 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2 PF00096.24 001078387.1_12425001_2 - 6.5e-15 54.5 93.4 0.00031 20.9 1.7 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_5 PF13909.4 001078387.1_12425001_2 - 1.4e-05 24.6 18.2 0.00047 19.7 2.3 8.3 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.4 001078387.1_12425001_2 - 1.5e-05 25.3 88.8 0.02 15.6 0.9 9.5 9 0 0 9 9 9 6 C2H2-type zinc finger GAGA PF09237.9 001078387.1_12425001_2 - 0.24 11.1 11.3 7.5 6.3 0.0 4.7 4 1 0 4 4 4 0 GAGA factor BolA PF01722.16 001078387.1_12425001_2 - 0.44 10.7 4.7 23 5.2 0.1 3.6 3 0 0 3 3 3 0 BolA-like protein DUF1299 PF06975.9 001078387.1_12425001_2 - 1.6 8.7 7.2 4.4 7.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1299) Rad50_zn_hook PF04423.12 001078387.1_12425001_2 - 2.4 7.9 7.6 4.6 7.0 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-met PF12874.5 001078387.1_12425001_2 - 3.6 8.0 42.2 1.7 9.0 1.1 7.8 7 1 0 7 7 7 0 Zinc-finger of C2H2 type Sld5 PF05916.9 001200633.1_26623001_3 - 6.2e-06 26.5 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Iso_dh PF00180.18 001200742.1_26624001_1 - 2.4e-109 365.5 0.0 2.9e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase S4 PF01479.23 001200145.2_26622001_1 - 1.1e-10 40.9 2.1 2.8e-10 39.6 2.1 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.17 001200145.2_26622001_1 - 9.4e-06 26.4 0.5 1.9e-05 25.4 0.2 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L14e PF01929.15 001200114.1_26621001_1 - 5.7e-32 109.9 8.5 5.7e-32 109.9 8.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.27 001200114.1_26621001_1 - 0.0014 18.4 0.3 0.0023 17.7 0.3 1.4 1 0 0 1 1 1 1 KOW motif Pterin_4a PF01329.17 001200222.2_26622001_1 - 1.6e-29 101.8 0.0 2.2e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase zf-RING_2 PF13639.4 001200961.1_26622001_1 - 2.9e-12 46.5 9.4 2.9e-12 46.5 9.4 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.3 001200961.1_26622001_1 - 1.1e-09 37.7 5.4 2.7e-09 36.5 5.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001200961.1_26622001_1 - 1.6e-08 34.1 9.6 4.8e-08 32.6 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001200961.1_26622001_1 - 1.9e-08 34.4 8.8 5.8e-08 32.8 8.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.4 001200961.1_26622001_1 - 1.2e-07 31.5 3.9 1.3e-07 31.4 2.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001200961.1_26622001_1 - 1.6e-06 27.8 8.5 1.6e-06 27.8 8.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001200961.1_26622001_1 - 3.1e-06 26.9 7.4 3.1e-06 26.9 7.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001200961.1_26622001_1 - 2e-05 24.2 6.7 2e-05 24.2 6.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001200961.1_26622001_1 - 4.4e-05 23.3 2.0 0.00011 22.1 2.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.4 001200961.1_26622001_1 - 7.4e-05 22.5 4.1 0.00027 20.7 1.1 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Orthoreo_P10 PF07204.9 001200961.1_26622001_1 - 0.068 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FANCL_C PF11793.6 001200961.1_26622001_1 - 0.68 10.0 9.7 20 5.3 9.7 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.3 001200961.1_26622001_1 - 6 6.4 14.8 0.031 13.8 5.4 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DAGAT PF03982.11 001201076.1_26623001_3 - 8.2e-128 425.3 0.0 9.9e-128 425.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.19 001201076.1_26623001_3 - 0.062 12.8 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Acyltransferase GnRH PF00446.15 001286296.1_25021001_1 - 0.0018 18.4 4.5 0.0032 17.6 4.5 1.4 1 0 0 1 1 1 1 Gonadotropin-releasing hormone TNF PF00229.16 001286849.1_01523001_1 - 9.2e-10 38.4 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family SYF2 PF08231.10 001323500.1_23923001_1 - 1e-53 181.9 11.9 1e-53 181.9 11.9 2.0 2 1 0 2 2 2 1 SYF2 splicing factor Ank_2 PF12796.5 001317145.1_01426001_1 - 3.2e-14 53.2 0.4 1.4e-05 25.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ion_trans PF00520.29 001317145.1_01426001_1 - 7.3e-13 48.2 21.3 1.1e-12 47.7 21.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.4 001317145.1_01426001_1 - 3.6e-10 39.0 0.1 0.002 18.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.28 001317145.1_01426001_1 - 1e-09 38.3 0.3 0.00044 20.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.4 001317145.1_01426001_1 - 2.7e-09 37.0 0.5 0.05 13.9 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.4 001317145.1_01426001_1 - 1e-08 35.4 0.4 0.01 16.3 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) MIP PF00230.18 001309963.1_23125001_2 - 1.6e-46 158.7 8.9 2.3e-46 158.2 8.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein 7tm_1 PF00001.19 001297460.1_43023001_3 - 2e-41 141.9 9.7 2.9e-41 141.3 9.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.7 001297460.1_43023001_3 - 3.4e-25 87.4 2.0 6.9e-25 86.4 2.0 1.5 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srsx PF10320.7 001297460.1_43023001_3 - 6.3e-06 25.6 10.0 9.3e-06 25.1 10.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.7 001297460.1_43023001_3 - 8.4e-06 25.2 14.6 0.00012 21.4 14.6 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.7 001297460.1_43023001_3 - 0.00034 19.9 17.2 0.0033 16.7 16.7 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001297460.1_43023001_3 - 0.00069 19.3 5.1 0.33 10.5 0.1 2.1 2 0 0 2 2 2 2 Olfactory receptor DUF3040 PF11239.6 001297460.1_43023001_3 - 0.042 14.0 6.9 0.82 9.8 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF2569 PF10754.7 001297460.1_43023001_3 - 0.4 11.0 12.9 0.39 11.0 5.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) FA_desaturase PF00487.22 001297460.1_43023001_3 - 1 9.0 8.9 1.1 8.9 2.3 2.2 2 0 0 2 2 2 0 Fatty acid desaturase TAS2R PF05296.11 001297460.1_43023001_3 - 2 7.3 11.8 3.8 6.4 1.9 2.1 2 0 0 2 2 2 0 Taste receptor protein (TAS2R) Ig_3 PF13927.4 001311341.1_37523001_1 - 2.2e-13 50.5 5.2 3.4e-08 33.8 0.1 2.9 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 001311341.1_37523001_1 - 3.6e-13 49.5 4.0 1.4e-08 34.9 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001311341.1_37523001_1 - 1.3e-07 31.6 11.3 0.0029 17.6 0.6 3.9 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.14 001311341.1_37523001_1 - 9.8e-06 25.4 2.2 0.00013 21.8 0.3 3.0 2 1 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.15 001311341.1_37523001_1 - 1.3e-05 25.2 11.2 0.52 10.4 0.3 4.9 2 1 0 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.10 001311341.1_37523001_1 - 0.00014 21.7 2.2 0.021 14.8 0.8 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain SIT PF15330.4 001311341.1_37523001_1 - 0.00072 19.8 1.5 0.00072 19.8 1.5 2.0 2 1 1 3 3 2 1 SHP2-interacting transmembrane adaptor protein, SIT Tmemb_9 PF05434.9 001311341.1_37523001_1 - 0.0079 15.9 3.0 0.018 14.8 3.0 1.7 1 1 0 1 1 1 1 TMEM9 Sigma_reg_N PF13800.4 001311341.1_37523001_1 - 0.018 15.2 0.4 0.11 12.7 0.2 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Ly49 PF08391.8 001311341.1_37523001_1 - 0.018 15.2 1.8 0.045 14.0 1.8 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Shisa PF13908.4 001311341.1_37523001_1 - 0.025 14.7 1.9 0.028 14.5 0.0 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator O-antigen_lig PF13425.4 001311341.1_37523001_1 - 0.054 12.2 0.6 0.076 11.7 0.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein EphA2_TM PF14575.4 001311341.1_37523001_1 - 0.057 14.1 2.4 0.15 12.8 2.4 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.6 001311341.1_37523001_1 - 0.15 11.9 1.7 0.39 10.5 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Vpu PF00558.17 001311341.1_37523001_1 - 0.25 11.0 2.6 0.55 9.9 2.6 1.5 1 0 0 1 1 1 0 Vpu protein TMEM154 PF15102.4 001311341.1_37523001_1 - 0.26 11.1 5.3 0.68 9.7 4.9 2.0 1 1 0 1 1 1 0 TMEM154 protein family Baculo_11_kDa PF06143.9 001311341.1_37523001_1 - 0.65 9.5 4.9 1.6 8.3 4.9 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family IncA PF04156.12 001311341.1_37523001_1 - 1.3 8.6 10.8 4.4 6.9 10.8 1.8 1 1 0 1 1 1 0 IncA protein DUF4446 PF14584.4 001311341.1_37523001_1 - 1.5 8.7 4.6 0.94 9.3 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4578 PF15147.4 001311341.1_37523001_1 - 3.1 8.5 7.0 0.43 11.3 2.5 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4578) DUF2681 PF10883.6 001311341.1_37523001_1 - 6.6 7.1 7.8 0.37 11.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Conotoxin PF02950.15 001311341.1_37523001_1 - 9.8 7.1 6.4 4.3 8.3 0.1 3.0 3 0 0 3 3 2 0 Conotoxin Pkinase PF00069.23 001319868.1_37524001_1 - 3.8e-73 246.0 0.0 5.2e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001319868.1_37524001_1 - 3.2e-42 144.5 0.0 5e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.3 001319868.1_37524001_1 - 8.7e-12 45.4 0.0 4e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.4 001319868.1_37524001_1 - 2.6e-07 30.1 0.0 4.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001319868.1_37524001_1 - 0.00033 19.9 0.2 0.0006 19.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001319868.1_37524001_1 - 0.00041 19.9 0.3 0.00071 19.1 0.3 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.7 001319868.1_37524001_1 - 0.032 12.9 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.21 001319868.1_37524001_1 - 0.032 14.0 0.0 0.22 11.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family 7tm_1 PF00001.19 001297458.1_43024001_3 - 1.4e-39 135.8 9.8 2.7e-39 134.9 9.8 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.7 001297458.1_43024001_3 - 9.3e-25 86.0 3.3 2e-24 84.9 3.3 1.6 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.7 001297458.1_43024001_3 - 2.4e-09 36.8 5.4 4.6e-09 35.9 5.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.7 001297458.1_43024001_3 - 3.6e-05 23.1 9.6 0.00011 21.6 9.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001297458.1_43024001_3 - 0.0086 15.7 8.7 0.16 11.5 8.7 2.2 1 1 0 1 1 1 1 Olfactory receptor Git3 PF11710.6 001297458.1_43024001_3 - 0.016 14.8 5.9 0.087 12.5 5.9 2.1 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 FA_desaturase PF00487.22 001297458.1_43024001_3 - 0.35 10.5 8.4 0.48 10.1 2.8 2.3 2 0 0 2 2 2 0 Fatty acid desaturase DUF4079 PF13301.4 001297458.1_43024001_3 - 1.3 9.1 8.7 4 7.5 3.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) PTPS PF01242.17 001297446.1_43022001_3 - 1.7e-23 82.7 0.1 3.4e-23 81.8 0.1 1.5 1 1 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase 7tm_1 PF00001.19 001314074.1_54023001_1 - 5.4e-46 156.9 13.3 7.3e-46 156.4 13.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.7 001314074.1_54023001_1 - 9.6e-26 89.2 3.3 2.3e-25 88.0 3.3 1.7 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.7 001314074.1_54023001_1 - 3e-14 52.9 15.5 1.8e-13 50.4 15.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.7 001314074.1_54023001_1 - 1.7e-08 34.0 15.7 2.7e-08 33.4 15.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.7 001314074.1_54023001_1 - 8.4e-07 28.5 13.0 8.4e-07 28.5 13.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001314074.1_54023001_1 - 2.6e-05 23.9 12.3 0.00012 21.7 12.3 1.9 1 1 0 1 1 1 1 Olfactory receptor TAS2R PF05296.11 001314074.1_54023001_1 - 0.00037 19.6 9.9 0.0054 15.7 2.2 2.2 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) DUF4079 PF13301.4 001314074.1_54023001_1 - 0.0056 16.7 4.1 0.15 12.1 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4079) 60KD_IMP PF02096.18 001314074.1_54023001_1 - 0.3 10.8 3.7 0.8 9.5 3.5 2.1 1 1 0 1 1 1 0 60Kd inner membrane protein FA_desaturase PF00487.22 001314074.1_54023001_1 - 2.3 7.8 11.8 0.17 11.5 0.5 2.3 2 1 0 2 2 2 0 Fatty acid desaturase DUF4407 PF14362.4 001314074.1_54023001_1 - 8.4 5.5 8.5 1.7 7.8 5.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MHC_II_alpha PF00993.18 001320031.1_35623001_1 - 6.5e-32 108.9 0.6 9.3e-32 108.4 0.6 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001320031.1_35623001_1 - 7.1e-28 95.6 0.4 1.3e-27 94.8 0.4 1.5 1 0 0 1 1 1 1 C1-set C-terminal domain C1-set PF07654.13 001320031.1_35623001_1 - 1.4e-23 83.0 0.0 2.8e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001320031.1_35623001_1 - 0.0027 18.1 0.0 0.0058 17.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Homeobox PF00046.27 001301787.1_23522001_1 - 4e-22 77.7 2.2 5.8e-22 77.1 2.2 1.2 1 0 0 1 1 1 1 Homeobox domain TF_Otx PF03529.11 001301787.1_23522001_1 - 3.8e-21 75.2 10.4 3.8e-21 75.2 10.4 2.2 1 1 1 2 2 2 1 Otx1 transcription factor 7tm_1 PF00001.19 001329059.1_43023001_1 - 2.9e-36 125.0 14.0 2.9e-36 125.0 14.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001329059.1_43023001_1 - 0.003 17.2 10.4 0.045 13.3 10.4 2.0 1 1 0 1 1 1 1 Olfactory receptor EF-hand_1 PF00036.30 001310359.1_02123001_1 - 5.5e-10 37.9 2.5 0.028 13.8 0.1 4.8 4 1 1 5 5 5 2 EF hand EF-hand_7 PF13499.4 001310359.1_02123001_1 - 2.5e-09 37.3 0.1 0.00068 19.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001310359.1_02123001_1 - 3e-09 35.9 1.0 0.0018 17.9 0.2 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.4 001310359.1_02123001_1 - 1.7e-05 24.3 0.3 0.17 11.6 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.4 001310359.1_02123001_1 - 0.0081 16.3 0.0 3.2 8.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain DUF4813 PF16072.3 001310359.1_02123001_1 - 0.039 13.5 4.8 0.063 12.8 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Cas9_REC PF16592.3 001310359.1_02123001_1 - 0.1 11.2 0.4 0.13 10.8 0.4 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 Ribosomal_60s PF00428.17 001310359.1_02123001_1 - 4 7.9 9.3 1.2 9.6 4.2 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein LSM14 PF12701.5 001310414.2_02126001_1 - 2.5e-33 113.9 0.0 4e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.8 001310414.2_02126001_1 - 1.1e-30 106.4 9.5 2.4e-30 105.4 7.0 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.4 001310414.2_02126001_1 - 4.3e-08 33.1 0.0 7.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3729 PF12526.6 001310414.2_02126001_1 - 8.8 7.8 8.8 20 6.7 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Lipocalin PF00061.21 001310343.1_02122001_1 - 5.7e-15 55.6 2.4 7.1e-15 55.3 2.4 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001310343.1_02122001_1 - 2.9e-09 36.8 1.3 3.7e-09 36.5 1.3 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_4 PF13648.4 001310343.1_02122001_1 - 0.032 15.1 2.7 0.069 14.0 2.7 1.6 1 1 0 1 1 1 0 Lipocalin-like domain Serum_albumin PF00273.18 001310394.1_02125001_3 - 8.6e-156 514.0 36.7 3e-57 193.1 13.1 3.1 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.8 001310394.1_02125001_3 - 6.3e-06 26.0 16.8 0.31 10.9 0.1 6.4 6 0 0 6 6 6 3 Vitamin D binding protein, domain III CYTL1 PF15153.4 001310394.1_02125001_3 - 0.0078 16.0 4.2 0.014 15.2 0.4 2.7 2 0 0 2 2 2 1 Cytokine-like protein 1 PPR_long PF17177.2 001310394.1_02125001_3 - 0.22 10.7 4.5 27 3.9 0.1 3.7 4 0 0 4 4 4 0 Pentacotripeptide-repeat region of PROPR DUF728 PF05304.10 001310394.1_02125001_3 - 1.2 8.9 5.3 12 5.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF728) Interfer-bind PF09294.8 001310411.1_02124001_3 - 4.8e-29 100.6 0.2 1.3e-28 99.2 0.0 1.9 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001310411.1_02124001_3 - 1.7e-16 59.9 0.9 2.9e-16 59.1 0.1 1.9 2 0 0 2 2 2 1 Tissue factor fn3 PF00041.19 001310411.1_02124001_3 - 1.9e-08 34.4 1.8 0.0048 17.1 0.1 2.7 2 1 0 2 2 2 2 Fibronectin type III domain Snf7 PF03357.19 001165070.2_36924001_2 - 2.4e-46 157.3 26.3 3.3e-46 156.9 26.3 1.2 1 0 0 1 1 1 1 Snf7 DUF342 PF03961.11 001165070.2_36924001_2 - 3.5 6.0 9.4 4.9 5.5 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) C1q PF00386.19 001281343.2_36922001_2 - 2.5e-32 111.6 0.1 3.1e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.16 001281343.2_36922001_2 - 9.4e-12 44.4 54.2 1e-07 31.5 25.5 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF1180 PF06679.10 001281343.2_36922001_2 - 0.16 12.3 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Kazal_1 PF00050.19 001353218.1_16021001_3 - 2.1e-15 56.3 3.3 3.5e-15 55.6 3.3 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 001353218.1_16021001_3 - 1.6e-08 34.5 1.1 2.6e-08 33.8 1.1 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Penaeidin PF05927.9 001353218.1_16021001_3 - 0.033 14.8 0.7 0.057 14.0 0.7 1.3 1 0 0 1 1 1 0 Penaeidin Myelin_MBP PF01669.15 205280.1_23525001_3 - 6.8e-72 240.9 10.6 9.4e-72 240.4 10.6 1.2 1 0 0 1 1 1 1 Myelin basic protein DUF3893 PF13032.4 200303.1_16122001_1 - 1.1 9.9 4.0 2.3 8.9 3.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3893) SUI1 PF01253.20 200303.1_16122001_2 - 3.9e-28 97.7 1.8 8.9e-28 96.5 1.8 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 LYRIC PF15686.3 200303.1_16122001_2 - 0.0016 18.0 6.1 0.002 17.6 6.1 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family OAD_gamma PF04277.11 200303.1_16122001_2 - 9.3 6.8 7.6 16 6.0 7.6 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SET PF00856.26 001045562.1_16124001_1 - 3.3e-14 53.5 0.0 5.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.9 001045562.1_16124001_1 - 1.1e-09 39.0 1.9 2.5e-09 37.8 1.9 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Ribosomal_L5e PF17144.2 199756.2_16123001_2 - 2.1e-90 300.8 0.1 2.1e-90 300.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.4 199756.2_16123001_2 - 4.8e-38 129.8 4.7 1.1e-37 128.6 4.7 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Methyltransf_3 PF01596.15 001160639.1_36923001_2 - 1.7e-67 226.6 0.6 2.1e-67 226.2 0.6 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001160639.1_36923001_2 - 4.1e-11 43.7 0.0 7.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 001160639.1_36923001_2 - 0.08 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Gal-bind_lectin PF00337.20 001160662.1_36922001_2 - 1.4e-27 95.7 0.2 2e-27 95.2 0.2 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin RA PF00788.21 001171853.1_36923001_1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain SH2 PF00017.22 001171853.1_36923001_3 - 2.7e-09 36.8 0.0 5.5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.14 001171853.1_36923001_3 - 2.6e-07 30.7 2.0 5e-07 29.8 2.0 1.5 1 0 0 1 1 1 1 SOCS box REV PF00424.16 001171853.1_36923001_3 - 0.076 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) T4_deiodinase PF00837.15 001124268.1_36925001_3 - 2e-85 285.8 0.0 2.5e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase CRF PF00473.15 001124286.1_36923001_1 - 7.9e-15 54.6 2.3 1.3e-14 53.9 2.3 1.3 1 0 0 1 1 1 1 Corticotropin-releasing factor family DUF4716 PF15837.3 001124286.1_36923001_2 - 0.77 9.7 4.9 1.6 8.7 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4716) CoA_binding PF02629.17 001160498.1_36923001_2 - 5.9e-30 103.7 1.1 1.2e-29 102.7 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.17 001160498.1_36923001_2 - 4.7e-24 84.8 0.2 7e-24 84.2 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.4 001160498.1_36923001_2 - 1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.4 001160498.1_36923001_2 - 0.0011 19.3 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain FOXP-CC PF16159.3 001246333.1_36925001_3 - 1.8e-28 98.8 2.6 4.7e-28 97.5 2.6 1.8 1 0 0 1 1 1 1 FOXP coiled-coil domain Forkhead PF00250.16 001246333.1_36925001_3 - 2.3e-24 85.4 0.2 4.8e-24 84.3 0.2 1.6 1 0 0 1 1 1 1 Forkhead domain Proteasome_A_N PF10584.7 023334.2_16122120_2 - 0.011 15.2 0.1 0.097 12.2 0.0 2.3 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature NHL PF01436.19 023334.2_16122120_2 - 0.072 13.0 0.5 9.3 6.4 0.0 3.7 4 0 0 4 4 4 0 NHL repeat Carb_anhydrase PF00194.19 137291.1_16123120_1 - 1e-75 254.5 0.2 1.2e-75 254.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF2254 PF10011.7 137291.1_16123120_3 - 0.19 10.4 0.0 0.24 10.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) zf-C3HC4_4 PF15227.4 037706.1_16125120_3 - 1.1e-13 50.9 11.9 1.1e-13 50.9 11.9 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.4 037706.1_16125120_3 - 5.2e-11 42.2 9.0 5.2e-11 42.2 9.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.23 037706.1_16125120_3 - 3.9e-09 36.1 9.6 3.9e-09 36.1 9.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 037706.1_16125120_3 - 8.8e-09 34.9 10.1 8.8e-09 34.9 10.1 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 037706.1_16125120_3 - 2.7e-07 30.2 7.3 2.7e-07 30.2 7.3 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 037706.1_16125120_3 - 8.1e-07 29.1 10.3 8.1e-07 29.1 10.3 3.5 3 0 0 3 3 3 1 Ring finger domain zf-B_box PF00643.22 037706.1_16125120_3 - 3.1e-06 27.1 9.3 3.1e-06 27.1 9.3 3.9 4 0 0 4 4 4 1 B-box zinc finger zf-RING_5 PF14634.4 037706.1_16125120_3 - 9.6e-05 22.1 9.2 9.6e-05 22.1 9.2 3.2 2 1 0 2 2 1 1 zinc-RING finger domain U-box PF04564.13 037706.1_16125120_3 - 0.0003 20.8 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.4 037706.1_16125120_3 - 0.0053 16.5 8.5 0.0053 16.5 8.5 3.2 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.4 037706.1_16125120_3 - 0.017 14.8 4.1 0.05 13.3 4.1 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein EF-hand_6 PF13405.4 137289.1_16122120_3 - 0.0087 15.8 0.0 0.047 13.5 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.4 137289.1_16122120_3 - 0.13 11.7 0.5 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 EF hand V-set PF07686.15 001124301.1_36923001_1 - 9.5e-26 90.0 0.1 2.9e-12 46.6 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.4 001124301.1_36923001_1 - 7.4e-11 42.4 1.0 1.4e-05 25.5 0.8 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001124301.1_36923001_1 - 2.4e-07 30.6 0.0 0.022 14.7 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.23 001124301.1_36923001_1 - 8.6e-07 28.9 1.1 0.00063 19.7 0.3 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 001124301.1_36923001_1 - 0.0013 18.9 5.9 0.0069 16.6 1.8 3.0 2 2 0 2 2 2 1 Immunoglobulin domain PTCRA PF15028.4 001124301.1_36923001_1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Ras PF00071.20 001165060.1_36923001_3 - 1.6e-57 193.5 0.0 2e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001165060.1_36923001_3 - 5.5e-23 81.3 0.0 8e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001165060.1_36923001_3 - 5.4e-10 38.9 0.0 9.5e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001165060.1_36923001_3 - 0.00094 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001165060.1_36923001_3 - 0.069 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001165060.1_36923001_3 - 0.073 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_membrane PF00664.21 001124656.1_36929001_1 - 2.4e-118 394.6 16.7 1.8e-67 227.8 8.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001124656.1_36929001_1 - 8.3e-70 233.5 0.1 2.6e-34 118.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.17 001124656.1_36929001_1 - 2.4e-13 49.9 0.1 1.7e-06 27.5 0.1 3.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.4 001124656.1_36929001_1 - 5.6e-08 33.2 0.2 0.015 15.5 0.0 3.0 2 2 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.14 001124656.1_36929001_1 - 1.2e-07 31.6 0.0 0.0048 16.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.4 001124656.1_36929001_1 - 2.5e-06 27.0 0.2 0.012 15.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.4 001124656.1_36929001_1 - 4.9e-06 26.7 0.3 0.076 13.1 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.4 001124656.1_36929001_1 - 2.6e-05 23.9 0.0 0.19 11.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.4 001124656.1_36929001_1 - 3.1e-05 23.7 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.10 001124656.1_36929001_1 - 0.00036 19.8 0.2 0.086 12.0 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.4 001124656.1_36929001_1 - 0.0012 18.9 0.4 0.84 9.7 0.2 3.2 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.7 001124656.1_36929001_1 - 0.0018 17.0 0.3 0.22 10.1 0.1 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.27 001124656.1_36929001_1 - 0.002 18.4 1.2 4 7.7 0.6 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.20 001124656.1_36929001_1 - 0.0032 17.7 0.0 7.7 6.8 0.0 3.9 4 0 0 4 4 4 0 RNA helicase AAA_5 PF07728.12 001124656.1_36929001_1 - 0.0062 16.4 0.0 4 7.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.4 001124656.1_36929001_1 - 0.0068 16.5 0.7 1.4 9.1 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.4 001124656.1_36929001_1 - 0.0076 16.0 0.0 1.1 8.9 0.0 3.0 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.15 001124656.1_36929001_1 - 0.0076 16.2 0.4 2.3 8.0 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 G-alpha PF00503.18 001124656.1_36929001_1 - 0.021 13.8 0.0 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.13 001124656.1_36929001_1 - 0.023 13.5 0.0 1.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein APS_kinase PF01583.18 001124656.1_36929001_1 - 0.03 14.1 0.0 1.2 8.9 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.4 001124656.1_36929001_1 - 0.07 13.5 0.8 2.4 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.4 001124656.1_36929001_1 - 0.11 12.6 0.0 12 6.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.23 001124656.1_36929001_1 - 0.14 11.7 0.1 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.4 001124656.1_36929001_1 - 0.14 11.6 0.1 14 5.1 0.0 3.1 4 0 0 4 4 3 0 AAA domain SR-25 PF10500.7 001165221.2_36923001_2 - 0.00024 20.6 37.4 0.0023 17.4 26.7 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF4298 PF14131.4 001165221.2_36923001_2 - 0.033 14.0 0.8 0.18 11.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) AP3D1 PF06375.9 001165221.2_36923001_2 - 1.8 8.7 27.8 0.12 12.5 16.1 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF2347 PF09804.7 001165221.2_36923001_2 - 5.2 6.4 9.5 3.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) UQ_con PF00179.24 001165240.2_36923001_3 - 7.4e-14 51.5 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001165240.2_36923001_3 - 0.075 13.2 0.0 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 RWD domain Pkinase PF00069.23 199885.1_16127001_3 - 1.1e-74 251.0 0.0 1.7e-74 250.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 199885.1_16127001_3 - 1.4e-44 152.2 0.0 2e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.17 199885.1_16127001_3 - 1.5e-20 72.5 0.0 2.8e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.4 199885.1_16127001_3 - 1.4e-06 27.7 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA PF00627.29 199885.1_16127001_3 - 8e-05 22.3 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.20 199885.1_16127001_3 - 0.00023 20.7 0.3 0.00044 19.8 0.3 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.12 199885.1_16127001_3 - 0.01 15.0 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.17 001124235.1_36924001_1 - 2.3e-150 500.6 0.0 2.3e-150 500.6 0.0 2.1 2 1 0 2 2 2 1 Actin DUF4604 PF15377.4 001124235.1_36924001_1 - 2.4 8.4 22.9 4.1 7.7 22.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) FAM176 PF14851.4 001124235.1_36924001_2 - 1.2 8.7 2.9 1.8 8.1 2.9 1.2 1 0 0 1 1 1 0 FAM176 family Herpes_UL52 PF03121.13 001165127.1_36923001_1 - 0.011 15.6 0.8 0.51 10.2 0.0 2.4 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase Exo_endo_phos PF03372.21 001165127.1_36923001_2 - 0.0004 20.5 0.1 0.00064 19.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family dUTPase PF00692.17 001006005.1_16122001_2 - 5.7e-46 155.2 0.0 7.6e-46 154.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase DUF4604 PF15377.4 001006005.1_16122001_2 - 0.00021 21.7 8.2 0.00032 21.1 8.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) PigN PF04987.12 001006005.1_16122001_2 - 0.2 10.3 0.4 0.26 10.0 0.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) 7TM_GPCR_Sru PF10322.7 001006005.1_16122001_2 - 0.34 10.1 3.3 0.48 9.6 3.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru O-ag_pol_Wzy PF14296.4 001006005.1_16122001_2 - 4.2 5.8 6.3 5.6 5.4 6.3 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy OAD_gamma PF04277.11 001006005.1_16122001_2 - 5.4 7.6 14.0 0.43 11.1 8.8 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.4 001006005.1_16122001_2 - 6.1 7.6 5.7 2 9.2 2.7 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SNARE_assoc PF09335.9 001020765.1_16124001_2 - 1.6e-19 70.4 7.4 1.6e-19 70.4 7.4 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4024 PF13216.4 001020765.1_16124001_3 - 0.073 12.9 0.3 0.25 11.2 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) HSP70 PF00012.18 001160520.1_36922001_1 - 4.6e-48 163.7 0.0 5.6e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Filament PF00038.19 001124743.1_36926001_3 - 2.2e-117 392.0 35.6 2.6e-117 391.8 35.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.3 001124743.1_36926001_3 - 1.2e-06 28.6 101.8 1.2e-06 28.6 101.8 4.9 2 2 2 4 4 1 1 Keratin type II head TPR_MLP1_2 PF07926.10 001124743.1_36926001_3 - 3.4e-06 27.0 25.0 0.00068 19.6 0.1 3.5 2 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.9 001124743.1_36926001_3 - 5e-05 22.2 26.2 0.0025 16.6 13.6 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein ADIP PF11559.6 001124743.1_36926001_3 - 8.8e-05 22.5 16.5 0.0052 16.8 7.4 3.3 3 1 1 4 4 3 2 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.7 001124743.1_36926001_3 - 9.3e-05 22.3 24.8 0.0029 17.5 10.4 3.1 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.4 001124743.1_36926001_3 - 0.00067 18.3 12.6 0.00095 17.8 12.3 1.4 1 1 0 1 1 1 1 AAA domain Jnk-SapK_ap_N PF09744.7 001124743.1_36926001_3 - 0.012 15.7 23.8 0.27 11.3 0.6 3.3 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF1192 PF06698.9 001124743.1_36926001_3 - 0.039 13.9 10.8 0.26 11.2 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FPP PF05911.9 001124743.1_36926001_3 - 0.043 12.0 22.8 0.15 10.2 12.4 2.1 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4201 PF13870.4 001124743.1_36926001_3 - 0.077 12.5 16.3 0.18 11.3 0.7 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4201) VirD1 PF07328.9 001124743.1_36926001_3 - 0.08 12.8 0.1 0.21 11.4 0.0 1.7 2 0 0 2 2 1 0 T-DNA border endonuclease VirD1 Alanine_zipper PF11839.6 001124743.1_36926001_3 - 0.086 13.0 7.0 0.26 11.4 7.0 1.8 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Baculo_PEP_C PF04513.10 001124743.1_36926001_3 - 0.15 11.9 11.3 1.8 8.4 0.7 3.8 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.12 001124743.1_36926001_3 - 0.19 11.4 26.3 0.75 9.4 12.8 3.5 1 1 3 4 4 4 0 IncA protein Cauli_AT PF03233.11 001124743.1_36926001_3 - 0.24 11.2 4.7 0.065 13.0 1.0 1.9 2 0 0 2 2 2 0 Aphid transmission protein Reo_sigmaC PF04582.10 001124743.1_36926001_3 - 0.37 10.0 3.7 4.9 6.3 0.2 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Golgin_A5 PF09787.7 001124743.1_36926001_3 - 0.58 9.4 25.6 1.1 8.6 3.5 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Cep57_MT_bd PF06657.11 001124743.1_36926001_3 - 0.96 9.8 12.0 2.1 8.7 2.1 3.7 2 2 2 4 4 3 0 Centrosome microtubule-binding domain of Cep57 DUF5082 PF16888.3 001124743.1_36926001_3 - 0.96 9.7 18.7 1.5 9.0 3.8 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) Occludin_ELL PF07303.11 001124743.1_36926001_3 - 1 10.0 10.2 0.13 12.8 3.7 2.7 1 1 3 4 4 3 0 Occludin homology domain DUF4407 PF14362.4 001124743.1_36926001_3 - 1.3 8.1 17.0 64 2.6 17.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1451 PF07295.9 001124743.1_36926001_3 - 1.7 8.5 12.0 1.5 8.8 1.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF883 PF05957.11 001124743.1_36926001_3 - 2.4 8.7 12.6 1.6 9.3 5.3 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) BRE1 PF08647.9 001124743.1_36926001_3 - 2.6 8.1 28.2 0.019 14.9 3.3 3.9 2 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase CALCOCO1 PF07888.9 001124743.1_36926001_3 - 3.3 6.1 27.3 12 4.1 26.5 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Rab5-bind PF09311.9 001124743.1_36926001_3 - 4.7 6.4 25.7 0.36 10.1 10.6 2.8 1 1 2 3 3 3 0 Rabaptin-like protein Rootletin PF15035.4 001124743.1_36926001_3 - 5 7.0 24.0 5.3 6.9 8.3 2.5 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF720 PF05302.9 001124743.1_36926001_3 - 6.5 6.5 8.0 1.5 8.6 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF720) HIT PF01230.21 001005593.2_16122001_2 - 4.2e-31 107.5 0.0 5.6e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.6 001005593.2_16122001_2 - 3.9e-22 78.8 0.0 5.4e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Pkinase PF00069.23 001030091.1_16124001_1 - 1.4e-66 224.5 0.0 1.7e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001030091.1_16124001_1 - 1.4e-34 119.4 0.0 2.1e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.22 001030091.1_16124001_1 - 7.4e-16 57.7 0.0 1.9e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 PB1 domain C1_1 PF00130.20 001030091.1_16124001_1 - 1.7e-15 56.5 9.2 3.4e-15 55.5 9.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.22 001030091.1_16124001_1 - 2.8e-06 27.8 2.3 6.6e-06 26.6 1.9 1.9 2 0 0 2 2 1 1 Protein kinase C terminal domain Kinase-like PF14531.4 001030091.1_16124001_1 - 3.2e-06 26.6 0.0 4.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001030091.1_16124001_1 - 0.012 14.8 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001030091.1_16124001_1 - 0.027 14.3 0.1 0.13 12.0 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_2 PF03107.14 001030091.1_16124001_1 - 0.033 14.4 3.1 0.069 13.3 3.1 1.5 1 0 0 1 1 1 0 C1 domain FTA2 PF13095.4 001030091.1_16124001_1 - 0.035 13.6 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 FYDLN_acid PF09538.8 001030091.1_16124001_1 - 0.07 13.7 0.3 0.22 12.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DZR PF12773.5 001030091.1_16124001_1 - 8.1 6.4 6.2 2.6 8.0 2.8 1.9 2 0 0 2 2 2 0 Double zinc ribbon 7tm_1 PF00001.19 001308970.2_16124001_2 - 2.3e-36 125.3 28.9 7.2e-36 123.7 28.9 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) E1-E2_ATPase PF00122.18 001308970.2_16124001_2 - 2.1 7.5 9.3 0.031 13.4 0.6 2.2 1 1 0 2 2 2 0 E1-E2 ATPase Mob1_phocein PF03637.15 001160540.2_36923001_1 - 8.4e-32 110.4 1.1 8.4e-32 110.4 1.1 1.7 2 1 0 2 2 2 1 Mob1/phocein family Gelsolin PF00626.20 001257146.1_16128001_1 - 2.2e-64 213.2 2.3 7.9e-16 57.6 0.0 6.7 6 0 0 6 6 6 6 Gelsolin repeat LRR_8 PF13855.4 001257146.1_16128001_1 - 2.6e-40 135.9 52.1 1.2e-08 34.4 11.8 6.7 5 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.5 001257146.1_16128001_1 - 1.5e-27 94.9 64.5 1.2e-07 31.7 2.4 8.8 4 1 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001257146.1_16128001_1 - 7.5e-05 22.2 23.5 0.067 12.5 3.1 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.31 001257146.1_16128001_1 - 0.0025 17.9 51.4 1.3 9.7 0.3 12.4 13 0 0 13 13 13 4 Leucine Rich Repeat LRR_5 PF13306.4 001257146.1_16128001_1 - 0.006 16.4 1.5 0.21 11.4 0.7 2.6 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_6 PF13516.4 001257146.1_16128001_1 - 1.1 9.3 57.5 2.8 8.1 0.3 10.7 12 0 0 12 12 12 0 Leucine Rich repeat CSTF_C PF14304.4 001257146.1_16128001_1 - 5 6.6 6.3 6.9 6.2 0.2 3.7 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal PI3Ka PF00613.18 137316.1_16126120_1 - 1.5e-57 193.9 0.7 3.2e-57 192.8 0.7 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.22 137316.1_16126120_1 - 5.8e-47 159.0 0.0 1.1e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3_PI4_kinase PF00454.25 137316.1_16126120_1 - 1.7e-14 54.1 0.0 3.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HEAT_2 PF13646.4 137316.1_16126120_1 - 0.015 15.6 0.2 0.033 14.4 0.2 1.6 1 0 0 1 1 1 0 HEAT repeats WD40 PF00400.30 130148.1_16127120_3 - 9.7e-26 89.4 15.0 1.5e-05 25.5 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 130148.1_16127120_3 - 4.7e-10 39.5 0.0 0.0055 16.8 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SR-25 PF10500.7 134974.1_16122120_1 - 0.32 10.4 5.0 0.42 10.0 5.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C2H2 PF00096.24 023328.1_16121120_1 - 2.4e-14 52.8 11.5 0.00017 21.7 0.9 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 023328.1_16121120_1 - 2.6e-13 49.4 10.7 0.00016 22.1 0.5 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.4 023328.1_16121120_1 - 2e-10 40.5 13.6 1.2e-05 25.4 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.4 023328.1_16121120_1 - 1.5e-08 34.3 7.4 0.0024 17.6 0.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.5 023328.1_16121120_1 - 7.6e-08 32.4 9.4 0.00082 19.6 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 023328.1_16121120_1 - 1.2e-07 31.8 7.5 0.016 15.4 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.12 023328.1_16121120_1 - 1.6e-05 24.5 1.3 0.037 13.7 0.0 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C2HE PF16278.3 023328.1_16121120_1 - 4.5e-05 23.7 12.6 0.0085 16.4 1.0 3.1 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.3 023328.1_16121120_1 - 0.00027 20.5 3.5 0.46 10.1 0.1 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.5 023328.1_16121120_1 - 0.00029 21.0 9.0 0.097 12.9 0.6 2.3 1 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.8 023328.1_16121120_1 - 0.0012 18.7 4.7 0.0017 18.3 1.2 2.3 2 0 0 2 2 2 1 Zinc ribbon domain zf-Di19 PF05605.10 023328.1_16121120_1 - 0.0024 18.0 10.5 0.082 13.1 0.9 2.4 1 1 2 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding C1_4 PF07975.10 023328.1_16121120_1 - 0.0025 17.9 7.3 0.027 14.6 2.4 2.5 1 1 1 2 2 2 2 TFIIH C1-like domain zf-C2H2_9 PF16293.3 023328.1_16121120_1 - 0.0031 17.2 4.2 0.023 14.4 0.1 2.6 2 1 1 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.3 023328.1_16121120_1 - 0.007 16.5 5.1 0.019 15.2 1.6 2.1 1 1 1 2 2 2 1 C2H2-type zinc ribbon BolA PF01722.16 023328.1_16121120_1 - 0.0081 16.3 0.8 1.6 8.9 0.1 2.2 2 0 0 2 2 2 1 BolA-like protein Elf1 PF05129.11 023328.1_16121120_1 - 0.0084 16.0 7.3 0.03 14.2 1.6 2.2 1 1 1 2 2 2 1 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.4 023328.1_16121120_1 - 0.0093 15.7 8.3 0.012 15.4 2.6 3.0 2 1 0 2 2 2 1 zinc-ribbon domain CpXC PF14353.4 023328.1_16121120_1 - 0.023 14.6 5.7 0.76 9.7 1.1 2.6 1 1 1 2 2 2 0 CpXC protein Prok-RING_1 PF14446.4 023328.1_16121120_1 - 0.069 13.0 6.1 3 7.7 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-Sec23_Sec24 PF04810.13 023328.1_16121120_1 - 0.083 12.8 4.9 0.25 11.3 0.7 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger ADK_lid PF05191.12 023328.1_16121120_1 - 0.16 11.9 3.3 3.4 7.6 1.4 2.6 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-BED PF02892.13 023328.1_16121120_1 - 0.19 11.7 5.9 2.3 8.2 0.6 2.4 2 0 0 2 2 2 0 BED zinc finger zf-trcl PF13451.4 023328.1_16121120_1 - 0.2 11.5 6.2 0.18 11.6 1.8 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain HypA PF01155.17 023328.1_16121120_1 - 0.27 11.1 6.5 7.2 6.5 6.3 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.10 023328.1_16121120_1 - 0.34 10.8 8.4 18 5.2 8.4 2.9 1 1 0 1 1 1 0 zinc-ribbons DUF2225 PF09986.7 023328.1_16121120_1 - 0.45 10.1 6.2 0.8 9.3 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) SprT-like PF10263.7 023328.1_16121120_1 - 0.61 9.8 8.1 0.54 10.0 2.9 2.1 1 1 1 2 2 2 0 SprT-like family zf-FPG_IleRS PF06827.12 023328.1_16121120_1 - 0.63 9.8 5.8 5.7 6.8 0.1 3.0 3 0 0 3 3 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_15 PF17032.3 023328.1_16121120_1 - 0.68 10.6 9.4 0.25 12.0 2.4 2.2 1 1 1 2 2 2 0 zinc-ribbon family C1_2 PF03107.14 023328.1_16121120_1 - 1.2 9.4 15.0 5.9 7.2 0.8 3.3 2 1 1 3 3 2 0 C1 domain RNA_POL_M_15KD PF02150.14 023328.1_16121120_1 - 2 8.2 8.4 3.9 7.3 0.3 3.1 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-RING_5 PF14634.4 023328.1_16121120_1 - 4 7.4 10.3 7.2 6.5 0.4 2.8 1 1 1 2 2 2 0 zinc-RING finger domain PAX PF00292.16 001305635.1_39124001_1 - 1.1e-71 238.5 0.9 1.7e-71 237.9 0.9 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.27 001305635.1_39124001_1 - 1.1e-23 82.6 6.8 2.8e-23 81.4 6.8 1.7 1 0 0 1 1 1 1 Homeobox domain Pax7 PF12360.6 001305635.1_39124001_1 - 1.5e-23 82.5 13.2 4.5e-23 81.0 13.2 1.9 1 0 0 1 1 1 1 Paired box protein 7 Homeobox_KN PF05920.9 001305635.1_39124001_1 - 5.6e-05 22.8 1.6 9.4e-05 22.1 0.8 1.8 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.4 001305635.1_39124001_1 - 6.8e-05 22.4 2.1 0.0026 17.4 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.4 001305635.1_39124001_1 - 0.0024 18.3 6.6 0.062 13.8 0.1 3.4 2 1 1 3 3 3 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.5 001305635.1_39124001_1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain bZIP_1 PF00170.19 001309021.1_39124001_2 - 1.2e-11 44.4 15.9 2.1e-11 43.6 15.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001309021.1_39124001_2 - 4e-06 26.7 15.2 6.9e-06 25.9 15.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF3450 PF11932.6 001309021.1_39124001_2 - 0.0033 16.6 5.4 0.0048 16.1 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) MCU PF04678.11 001309021.1_39124001_2 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter ZapB PF06005.10 001309021.1_39124001_2 - 0.028 14.7 8.4 0.028 14.7 8.4 1.7 1 1 1 2 2 2 0 Cell division protein ZapB SPX PF03105.17 001309021.1_39124001_2 - 0.078 12.8 17.3 0.012 15.5 13.4 1.4 1 1 1 2 2 2 0 SPX domain Fez1 PF06818.13 001309021.1_39124001_2 - 0.1 12.9 9.4 0.18 12.1 9.4 1.3 1 0 0 1 1 1 0 Fez1 EMP24_GP25L PF01105.22 001309021.1_39124001_2 - 0.18 11.6 1.9 0.37 10.6 1.9 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD bZIP_Maf PF03131.15 001309021.1_39124001_2 - 0.4 11.1 7.6 0.7 10.3 7.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.12 001309021.1_39124001_2 - 0.44 10.2 7.5 0.87 9.2 7.5 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.10 001309021.1_39124001_2 - 0.61 9.3 7.0 0.88 8.8 7.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.13 001309021.1_39124001_2 - 1.1 9.0 4.8 2 8.1 4.8 1.4 1 0 0 1 1 1 0 Septum formation initiator AAA_13 PF13166.4 001309021.1_39124001_2 - 1.1 7.7 7.6 1.9 6.9 7.6 1.3 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.13 001309021.1_39124001_2 - 1.3 8.7 9.6 2.2 8.0 9.6 1.2 1 0 0 1 1 1 0 Mnd1 family Syntaxin-6_N PF09177.9 001309021.1_39124001_2 - 2.1 8.8 7.5 1.6 9.2 3.9 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF342 PF03961.11 001309021.1_39124001_2 - 3.2 6.1 7.0 4.3 5.7 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMPIT PF07851.11 001309021.1_39124001_2 - 8.7 5.3 7.6 13 4.8 7.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-nanos PF05741.11 001122828.1_39122001_1 - 1.8e-25 88.8 5.0 4.5e-25 87.5 5.0 1.7 1 0 0 1 1 1 1 Nanos RNA binding domain Cyt-b5 PF00173.26 001105102.1_39124001_1 - 3.1e-12 46.3 0.0 5.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M10 PF00413.22 001104880.1_39126001_1 - 9.4e-67 223.6 0.0 3.4e-66 221.8 0.0 1.8 1 1 0 1 1 1 1 Matrixin fn2 PF00040.17 001104880.1_39126001_1 - 1.1e-54 182.3 34.3 4.8e-18 65.0 6.3 3.9 3 0 0 3 3 3 3 Fibronectin type II domain Hemopexin PF00045.17 001104880.1_39126001_1 - 1.5e-27 95.1 8.5 4.1e-07 29.7 0.0 4.5 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.16 001104880.1_39126001_1 - 3.7e-10 39.7 0.9 7.4e-10 38.8 0.9 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.22 001104880.1_39126001_1 - 0.027 13.9 0.0 0.8 9.2 0.0 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.4 001104880.1_39126001_1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.3 001104880.1_39126001_1 - 0.078 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.4 001104880.1_39126001_1 - 0.096 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.7 001104880.1_39126001_1 - 0.1 11.4 0.4 0.15 10.8 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 ANF_receptor PF01094.26 001104713.1_39125001_1 - 3.7e-45 154.4 0.0 4.4e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Sec23_trunk PF04811.13 001201520.1_39127001_1 - 2.4e-83 279.3 0.4 3.6e-83 278.7 0.4 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.13 001201520.1_39127001_1 - 3.5e-22 78.0 0.3 8.3e-22 76.8 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.10 001201520.1_39127001_1 - 7.3e-19 68.2 0.0 1.7e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.13 001201520.1_39127001_1 - 1e-13 50.9 11.1 3.6e-13 49.2 11.1 2.0 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.20 001201520.1_39127001_1 - 2.9e-07 30.1 0.0 9.5e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat GDP_Man_Dehyd PF16363.3 001201520.1_39127001_1 - 0.15 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase T-box PF00907.20 001201500.1_39124001_1 - 2.9e-79 265.5 0.0 4.7e-79 264.8 0.0 1.3 1 0 0 1 1 1 1 T-box Hormone_recep PF00104.28 001110789.1_39123001_1 - 1.9e-20 73.2 0.0 4e-20 72.2 0.0 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Pkinase PF00069.23 001278896.1_39127001_1 - 4.3e-45 154.0 0.0 6.2e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.10 001278896.1_39127001_1 - 7.7e-42 142.3 0.0 1.5e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.15 001278896.1_39127001_1 - 5.4e-26 91.3 0.0 8.4e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.4 001278896.1_39127001_1 - 3.1e-08 33.4 0.1 0.0061 16.0 0.1 2.3 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.19 001278896.1_39127001_1 - 1.6e-06 27.6 1.3 0.016 15.0 0.0 3.4 4 0 0 4 4 4 2 PQQ enzyme repeat APH PF01636.21 001278896.1_39127001_1 - 2.6e-05 24.1 2.3 0.021 14.6 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.12 001278896.1_39127001_1 - 0.0011 18.2 0.1 0.002 17.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_3 PF13570.4 001278896.1_39127001_1 - 0.21 12.0 1.9 5.3 7.5 0.0 4.1 6 0 0 6 6 6 0 PQQ-like domain zf-RING_UBOX PF13445.4 001278896.1_39127001_3 - 0.14 12.0 3.7 0.36 10.7 1.0 2.8 2 0 0 2 2 2 0 RING-type zinc-finger MIF PF01187.16 001200304.1_26622001_2 - 1.1e-46 157.7 0.0 1.6e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.19 001200304.1_26622001_2 - 0.0097 15.7 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 1 Tautomerase enzyme MIF PF01187.16 001309981.1_23122001_3 - 6.3e-46 155.2 0.0 7.6e-46 155.0 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.19 001309981.1_23122001_3 - 0.078 12.8 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme MIF PF01187.16 001303400.1_27622001_3 - 8.5e-47 158.0 0.0 1e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.19 001303400.1_27622001_3 - 0.019 14.8 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme ATP-gua_Ptrans PF00217.17 001200451.1_26623001_1 - 6e-97 323.9 0.0 8.1e-97 323.5 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.13 001200451.1_26623001_1 - 1.3e-33 115.1 0.0 2.3e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain RPN7 PF10602.7 001201265.1_26623001_1 - 1.1e-58 197.7 2.0 2e-58 196.8 2.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.25 001201265.1_26623001_1 - 6e-17 61.9 0.1 4.1e-16 59.3 0.1 2.2 2 0 0 2 2 2 1 PCI domain Ocnus PF05005.13 001201196.1_26622001_2 - 3.4e-40 136.3 0.2 4.5e-40 136.0 0.2 1.2 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Neur_chan_LBD PF02931.21 001323060.1_54029001_1 - 1.1e-72 243.9 1.1 1.5e-72 243.4 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001323060.1_54029001_1 - 1.5e-64 218.2 0.0 2.1e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Orn_Arg_deC_N PF02784.14 001292044.1_30825001_1 - 2e-62 210.7 0.0 2.5e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001292044.1_30825001_1 - 7.4e-20 71.0 0.0 1.8e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ODC_AZ PF02100.15 001291881.2_30822001_2 - 1e-21 76.9 0.0 1.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Tropomyosin PF00261.18 001032538.1_12422001_2 - 8.3e-95 316.5 75.0 1e-89 299.9 53.2 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.5 001032538.1_12422001_2 - 4.9e-33 114.1 61.0 1.3e-31 109.5 35.7 3.0 2 1 0 2 2 2 2 Tropomyosin like CLZ PF16526.3 001032538.1_12422001_2 - 8e-11 42.0 8.8 8e-11 42.0 8.8 5.0 2 2 3 5 5 5 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.10 001032538.1_12422001_2 - 6.3e-07 29.4 27.1 0.0022 17.9 8.9 3.4 1 1 1 3 3 3 3 Laminin Domain II XhlA PF10779.7 001032538.1_12422001_2 - 0.004 17.2 44.3 0.006 16.6 1.1 5.8 3 1 2 5 5 5 2 Haemolysin XhlA Mnd1 PF03962.13 001032538.1_12422001_2 - 0.0045 16.7 14.6 0.0045 16.7 14.6 3.8 1 1 3 4 4 4 1 Mnd1 family DUF1515 PF07439.9 001032538.1_12422001_2 - 0.07 13.0 0.6 0.07 13.0 0.6 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1515) WES_acyltransf PF03007.14 001032538.1_12422001_2 - 0.15 11.7 2.1 0.43 10.2 2.1 1.8 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain AAA_13 PF13166.4 001032538.1_12422001_2 - 0.25 9.8 41.6 0.99 7.8 29.7 2.1 1 1 1 2 2 2 0 AAA domain Reo_sigmaC PF04582.10 001032538.1_12422001_2 - 0.26 10.5 7.6 0.64 9.2 0.5 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.10 001032538.1_12422001_2 - 0.29 11.0 21.8 0.38 10.6 4.3 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.9 001032538.1_12422001_2 - 1.1 9.2 25.7 0.24 11.4 2.7 4.2 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Lebercilin PF15619.4 001032538.1_12422001_2 - 1.7 8.1 53.7 15 5.0 10.5 3.3 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease BST2 PF16716.3 001032538.1_12422001_2 - 1.8 9.0 38.4 1.4 9.5 0.7 4.3 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 Golgin_A5 PF09787.7 001032538.1_12422001_2 - 2.2 7.5 46.2 1.4 8.1 10.8 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF2721 PF11026.6 001032538.1_12422001_2 - 3.1 7.5 6.0 9.4 6.0 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Fez1 PF06818.13 001032538.1_12422001_2 - 3.3 8.0 45.1 18 5.6 20.6 2.8 1 1 2 3 3 3 0 Fez1 DUF2333 PF10095.7 001032538.1_12422001_2 - 4.6 6.1 12.6 0.34 9.8 6.7 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) Flagellin_C PF00700.19 001032538.1_12422001_2 - 8.3 6.7 10.3 1.4 9.2 1.3 3.4 2 1 2 4 4 4 0 Bacterial flagellin C-terminal helical region IncA PF04156.12 001032538.1_12422001_2 - 8.4 6.0 49.4 0.18 11.4 22.9 2.5 1 1 1 2 2 2 0 IncA protein DUF2781 PF10914.6 130902.1_53522120_2 - 0.07 13.4 0.4 0.11 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) GSHPx PF00255.17 130902.1_53522120_3 - 2.9e-32 110.3 0.0 4e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AAA PF00004.27 001293067.1_01423001_1 - 6.4e-43 146.2 0.0 1.6e-42 144.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293067.1_01423001_1 - 3e-07 30.6 0.0 7.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293067.1_01423001_1 - 4.2e-06 26.7 0.0 2e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293067.1_01423001_1 - 6.4e-06 26.5 0.2 8.7e-05 22.8 0.0 2.6 3 1 1 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293067.1_01423001_1 - 4.3e-05 23.7 0.9 0.0066 16.6 0.2 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293067.1_01423001_1 - 0.00012 21.3 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293067.1_01423001_1 - 0.002 17.0 0.0 0.0039 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293067.1_01423001_1 - 0.0023 17.6 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293067.1_01423001_1 - 0.0023 18.0 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293067.1_01423001_1 - 0.004 17.5 0.2 0.024 15.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.19 001293067.1_01423001_1 - 0.0081 15.4 0.1 0.019 14.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.9 001293067.1_01423001_1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.11 001293067.1_01423001_1 - 0.011 15.0 0.0 0.029 13.6 0.0 1.7 1 0 0 1 1 1 0 KaiC PhoH PF02562.14 001293067.1_01423001_1 - 0.013 14.9 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein RILP PF11461.6 001293067.1_01423001_1 - 0.025 14.7 3.4 0.062 13.4 3.4 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_28 PF13521.4 001293067.1_01423001_1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.24 001293067.1_01423001_1 - 0.033 13.8 0.1 0.14 11.7 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293067.1_01423001_1 - 0.036 13.7 0.1 0.079 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.15 001293067.1_01423001_1 - 0.053 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293067.1_01423001_1 - 0.058 12.3 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.4 001293067.1_01423001_1 - 0.066 12.6 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.11 001293067.1_01423001_1 - 0.069 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.4 001293067.1_01423001_1 - 0.071 12.7 0.4 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.4 001293067.1_01423001_1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001293067.1_01423001_1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.4 001293067.1_01423001_1 - 0.11 12.9 0.5 0.58 10.5 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.4 001293067.1_01423001_1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SlyX PF04102.10 001293067.1_01423001_1 - 0.22 12.0 2.4 0.7 10.4 2.4 1.9 1 0 0 1 1 1 0 SlyX DivIC PF04977.13 001293067.1_01423001_1 - 0.32 10.7 3.0 0.74 9.5 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Laminin_II PF06009.10 001293067.1_01423001_1 - 0.33 10.8 3.6 1.5 8.7 1.0 2.6 3 0 0 3 3 3 0 Laminin Domain II MscS_porin PF12795.5 001293067.1_01423001_1 - 8.7 5.7 12.7 14 5.0 12.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA PF00004.27 001293068.1_01423001_1 - 6.4e-43 146.2 0.0 1.6e-42 144.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293068.1_01423001_1 - 3e-07 30.6 0.0 7.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293068.1_01423001_1 - 4.2e-06 26.7 0.0 2e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293068.1_01423001_1 - 6.4e-06 26.5 0.2 8.7e-05 22.8 0.0 2.6 3 1 1 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293068.1_01423001_1 - 4.3e-05 23.7 0.9 0.0066 16.6 0.2 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293068.1_01423001_1 - 0.00012 21.3 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293068.1_01423001_1 - 0.002 17.0 0.0 0.0039 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293068.1_01423001_1 - 0.0023 17.6 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293068.1_01423001_1 - 0.0023 18.0 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293068.1_01423001_1 - 0.004 17.5 0.2 0.024 15.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.19 001293068.1_01423001_1 - 0.0081 15.4 0.1 0.019 14.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.9 001293068.1_01423001_1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.11 001293068.1_01423001_1 - 0.011 15.0 0.0 0.029 13.6 0.0 1.7 1 0 0 1 1 1 0 KaiC PhoH PF02562.14 001293068.1_01423001_1 - 0.013 14.9 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein RILP PF11461.6 001293068.1_01423001_1 - 0.025 14.7 3.4 0.062 13.4 3.4 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_28 PF13521.4 001293068.1_01423001_1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.24 001293068.1_01423001_1 - 0.033 13.8 0.1 0.14 11.7 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293068.1_01423001_1 - 0.036 13.7 0.1 0.079 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.15 001293068.1_01423001_1 - 0.053 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293068.1_01423001_1 - 0.058 12.3 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.4 001293068.1_01423001_1 - 0.066 12.6 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.11 001293068.1_01423001_1 - 0.069 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.4 001293068.1_01423001_1 - 0.071 12.7 0.4 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.4 001293068.1_01423001_1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001293068.1_01423001_1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.4 001293068.1_01423001_1 - 0.11 12.9 0.5 0.58 10.5 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.4 001293068.1_01423001_1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SlyX PF04102.10 001293068.1_01423001_1 - 0.22 12.0 2.4 0.7 10.4 2.4 1.9 1 0 0 1 1 1 0 SlyX DivIC PF04977.13 001293068.1_01423001_1 - 0.32 10.7 3.0 0.74 9.5 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Laminin_II PF06009.10 001293068.1_01423001_1 - 0.33 10.8 3.6 1.5 8.7 1.0 2.6 3 0 0 3 3 3 0 Laminin Domain II MscS_porin PF12795.5 001293068.1_01423001_1 - 8.7 5.7 12.7 14 5.0 12.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Orn_Arg_deC_N PF02784.14 001291759.1_01425001_3 - 5e-59 199.6 0.0 6.4e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291759.1_01425001_3 - 9.6e-22 77.0 0.0 1.9e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain RCC1 PF00415.16 001205222.1_12425001_3 - 2.2e-68 226.6 6.5 3.5e-10 40.2 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 001205222.1_12425001_3 - 5.1e-30 102.5 22.1 3.1e-10 39.5 1.3 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Leptin PF02024.13 001354912.1_13322001_1 - 1.9e-16 60.0 0.0 3.4e-16 59.2 0.0 1.3 1 1 0 1 1 1 1 Leptin SRCR PF00530.16 001294196.1_15725001_3 - 1.8e-30 105.3 2.6 1.8e-30 105.3 2.6 1.8 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain BACK PF07707.13 001294196.1_15725001_3 - 2.6e-12 46.6 0.3 5.6e-12 45.5 0.3 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch SRCR_2 PF15494.4 001294196.1_15725001_3 - 0.00078 19.8 0.1 0.0022 18.3 0.1 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain BTB PF00651.29 001294196.1_15725001_3 - 0.0095 16.0 0.0 0.031 14.4 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain SelP_N PF04592.12 001348999.1_53422001_2 - 1.3e-78 263.4 0.0 1.7e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Selenoprotein P, N terminal region HA2 PF04408.21 207093.1_16125001_2 - 0.28 11.4 2.1 0.74 10.1 2.1 1.6 1 0 0 1 1 1 0 Helicase associated domain (HA2) DUF4604 PF15377.4 207093.1_16125001_2 - 0.9 9.8 19.4 1.4 9.2 19.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) OAD_gamma PF04277.11 207093.1_16125001_2 - 7.9 7.0 9.5 17 6.0 9.5 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Connexin PF00029.17 207093.1_16125001_3 - 1.4e-90 302.9 2.3 1.4e-90 302.9 2.3 2.1 2 0 0 2 2 2 1 Connexin SNF5 PF04855.10 001006818.1_53524001_3 - 1.7e-56 191.5 0.8 1.5e-29 103.3 0.1 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 DUF1679 PF07914.9 001006818.1_53524001_3 - 0.0076 15.0 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) LIN52 PF10044.7 001007937.1_23527001_2 - 1.4e-37 128.1 0.1 2.6e-37 127.3 0.1 1.4 1 0 0 1 1 1 1 Retinal tissue protein Cofilin_ADF PF00241.18 001030589.1_23526001_1 - 1.4e-40 138.3 2.4 5.1e-22 78.2 0.7 2.6 3 0 0 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein MCM PF00493.21 001087997.1_53426001_2 - 4.9e-137 456.3 0.1 8.2e-137 455.6 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_OB PF17207.1 001087997.1_53426001_2 - 5.3e-34 116.7 0.8 9.3e-34 115.9 0.8 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.4 001087997.1_53426001_2 - 4.3e-22 78.5 4.1 1e-21 77.3 3.3 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.19 001087997.1_53426001_2 - 1.9e-08 33.9 0.1 4.4e-06 26.1 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.12 001087997.1_53426001_2 - 1.6e-05 24.8 0.0 3.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_bind PF09739.7 001087997.1_53426001_2 - 0.0011 17.4 0.6 0.0023 16.3 0.6 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor AAA_3 PF07726.9 001087997.1_53426001_2 - 0.017 14.8 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.24 001087997.1_53426001_2 - 0.1 12.2 0.0 0.35 10.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain P3A PF08727.9 001104668.1_39124001_1 - 0.15 11.3 1.1 0.29 10.4 1.1 1.3 1 0 0 1 1 1 0 Poliovirus 3A protein like Cyclin_N PF00134.21 001104668.1_39124001_3 - 1.8e-43 147.3 0.5 3.4e-43 146.4 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001104668.1_39124001_3 - 7.5e-35 119.5 0.7 1.5e-34 118.5 0.7 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Hist_deacetyl PF00850.17 204156.1_23527001_1 - 7.4e-83 278.4 0.1 1.4e-82 277.5 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain RNA_polI_A34 PF08208.9 204156.1_23527001_1 - 5 7.1 19.6 7.4 6.5 19.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 7tm_1 PF00001.19 001291266.1_04123001_1 - 2.9e-39 134.8 18.9 4.7e-39 134.1 18.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001291266.1_04123001_1 - 0.00011 21.5 4.2 0.00011 21.5 4.2 3.2 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2975 PF11188.6 001291266.1_04123001_1 - 0.012 15.3 2.3 0.012 15.3 2.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) 7TM_GPCR_Srx PF10328.7 001291266.1_04123001_1 - 3.7 6.6 20.3 15 4.7 20.1 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF962 PF06127.9 001291266.1_04123001_1 - 7.8 6.5 7.3 1.2 9.1 1.3 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Orn_Arg_deC_N PF02784.14 001292029.1_04127001_1 - 9.5e-57 192.1 0.0 1.3e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001292029.1_04127001_1 - 5.7e-19 68.1 0.0 1.1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SOXp PF12336.6 001319965.1_04123001_1 - 2.9e-36 124.2 2.2 2.9e-36 124.2 2.2 2.7 3 0 0 3 3 3 1 SOX transcription factor HMG_box PF00505.17 001319965.1_04123001_1 - 7e-28 96.7 3.2 1.1e-27 96.1 3.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001319965.1_04123001_1 - 1.1e-11 45.0 2.4 1.8e-11 44.3 2.4 1.4 1 0 0 1 1 1 1 HMG-box domain FTP PF07504.11 001319965.1_04123001_1 - 0.0088 15.7 0.6 0.016 14.8 0.6 1.4 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Sporozoite_P67 PF05642.9 001319965.1_04123001_1 - 4.2 5.2 9.6 6.8 4.5 9.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ODC_AZ PF02100.15 001292010.1_04123001_1 - 3e-19 69.0 0.0 4.4e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme FAD_binding_7 PF03441.12 001329367.1_27324001_1 - 2.2e-68 229.4 0.6 2.2e-68 229.4 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.16 001329367.1_27324001_1 - 3.9e-42 143.9 0.0 7.3e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase DUF3128 PF11326.6 001329367.1_27324001_1 - 0.12 12.6 1.2 2.1 8.6 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) ODC_AZ PF02100.15 001291919.1_04124001_1 - 1.3e-18 66.9 0.0 2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme TGFb_propeptide PF00688.16 001291252.1_04125001_1 - 8.6e-52 176.2 0.5 1.2e-51 175.7 0.5 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 001291252.1_04125001_1 - 3.7e-34 117.6 0.6 6.2e-34 116.9 0.6 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain CART PF06373.9 001291260.1_04122001_1 - 9.8e-39 131.3 1.8 1.4e-38 130.7 1.8 1.2 1 0 0 1 1 1 1 Cocaine and amphetamine regulated transcript protein (CART) Homeobox PF00046.27 001291261.1_04128001_3 - 2e-23 81.9 4.5 3.4e-23 81.1 4.5 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.15 001291261.1_04128001_3 - 1.5e-08 34.1 2.2 3.1e-08 33.0 2.2 1.6 1 0 0 1 1 1 1 OAR domain HSP90 PF00183.16 001291257.1_04126001_1 - 1.6e-237 789.4 28.7 2.1e-237 789.0 28.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.24 001291257.1_04126001_1 - 2.1e-14 53.9 0.1 5.9e-14 52.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001291257.1_04126001_1 - 1.3e-11 44.3 0.1 3.4e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crystall PF00030.17 001320208.1_04122001_1 - 6e-55 183.3 5.6 2.6e-27 94.7 0.2 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001320208.1_04122001_1 - 1e-07 31.6 0.8 0.0014 18.3 0.1 2.5 2 1 0 2 2 2 2 Peptidase inhibitor family I36 TagA PF12561.6 001320208.1_04122001_1 - 0.011 15.7 1.5 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein ODC_AZ PF02100.15 001291392.1_04123001_2 - 2.1e-20 72.7 0.0 3.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Hormone_3 PF00159.16 001291253.1_04122001_3 - 5.4e-16 58.3 1.2 8.9e-16 57.6 1.2 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide Homeobox PF00046.27 001291264.1_04125001_3 - 3.8e-23 80.9 2.7 6.7e-23 80.1 2.7 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.15 001291264.1_04125001_3 - 3.1e-07 29.8 2.4 6.1e-07 28.9 2.4 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.9 001291264.1_04125001_3 - 0.016 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain PAX PF00292.16 001291265.1_04125001_2 - 5.5e-71 236.2 0.7 9.5e-71 235.4 0.7 1.4 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.27 001291265.1_04125001_2 - 8.3e-23 79.8 4.5 1.9e-22 78.7 4.5 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.4 001291265.1_04125001_2 - 0.0037 16.9 0.0 0.015 15.0 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.5 001291265.1_04125001_2 - 0.0077 15.7 0.0 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 InsA C-terminal domain HTH_28 PF13518.4 001291265.1_04125001_2 - 0.39 10.8 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Period_C PF12114.6 001291258.1_04129001_1 - 5.9e-85 283.7 6.2 5.9e-85 283.7 6.2 4.1 4 0 0 4 4 4 1 Period protein 2/3C-terminal region PAS_3 PF08447.10 001291258.1_04129001_1 - 8.8e-12 45.0 0.0 8.6e-11 41.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.4 001291258.1_04129001_1 - 1.8e-09 37.6 0.0 7.1e-08 32.4 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.23 001291258.1_04129001_1 - 2.6e-07 30.5 0.0 0.00076 19.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold HH_signal PF01085.16 001291255.1_04124001_2 - 4.7e-87 289.5 0.0 7.1e-87 288.9 0.0 1.3 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Hint PF01079.18 001291255.1_04124001_2 - 4.5e-82 274.6 0.1 6.3e-82 274.1 0.1 1.2 1 0 0 1 1 1 1 Hint module Peptidase_M15_3 PF08291.9 001291255.1_04124001_2 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M15 Vint PF14623.4 001291255.1_04124001_2 - 0.031 14.0 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Hint-domain Gcd10p PF04189.11 001291255.1_04124001_2 - 0.035 13.1 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Gcd10p family SOTI PF17079.3 001291255.1_04124001_2 - 0.21 11.9 0.6 0.59 10.4 0.1 2.0 2 0 0 2 2 2 0 Male-specific protein scotti FAD_binding_7 PF03441.12 001291262.1_04124001_1 - 1.1e-68 230.4 0.6 2e-68 229.5 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.16 001291262.1_04124001_1 - 3.3e-43 147.4 0.0 6e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Crystall PF00030.17 001320206.1_04122001_2 - 1.4e-59 198.1 1.6 7.6e-29 99.6 0.4 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001320206.1_04122001_2 - 4.2e-09 36.1 0.6 0.0048 16.7 0.0 3.2 1 1 2 3 3 3 3 Peptidase inhibitor family I36 Trypan_PARP PF05887.9 001320206.1_04122001_2 - 0.05 13.5 14.5 0.073 13.0 14.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.9 001320206.1_04122001_3 - 5 7.0 18.0 0.3 11.0 7.8 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CitMHS PF03600.14 001320209.1_04126001_1 - 1.5e-56 191.7 17.4 1.5e-56 191.7 17.4 1.9 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.17 001320209.1_04126001_1 - 9.9e-16 57.7 31.0 1.2e-10 40.9 11.8 2.3 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region ArsB PF02040.13 001320209.1_04126001_1 - 2e-07 30.6 25.5 0.00022 20.6 9.8 2.6 2 1 0 2 2 2 2 Arsenical pump membrane protein DUF4491 PF14898.4 001320209.1_04126001_1 - 2.2 8.6 9.4 0.15 12.4 2.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Crystall PF00030.17 001318743.1_04123001_1 - 2.6e-55 184.4 10.3 5.4e-29 100.1 2.3 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin DUF3188 PF11384.6 001318743.1_04123001_2 - 0.083 12.5 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) 3HCDH_N PF02737.16 001319964.1_04123001_3 - 7.2e-45 152.9 0.0 1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.20 001319964.1_04123001_3 - 1.6e-14 54.1 0.0 3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.17 001319964.1_04123001_3 - 0.002 17.3 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.13 001319964.1_04123001_3 - 0.0041 17.2 0.1 0.0081 16.2 0.1 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.21 001319964.1_04123001_3 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.4 001319964.1_04123001_3 - 0.049 13.9 0.1 0.084 13.2 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.23 001319964.1_04123001_3 - 0.099 12.0 0.1 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Pyr_redox PF00070.25 001319964.1_04123001_3 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase wnt PF00110.17 001088168.1_53424001_1 - 4.8e-92 308.6 22.7 6.3e-92 308.2 22.7 1.1 1 0 0 1 1 1 1 wnt family Fer4_19 PF06902.9 001088168.1_53424001_2 - 0.021 14.7 0.5 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Ank_2 PF12796.5 001012915.1_23529001_2 - 5.9e-187 606.7 103.4 8.5e-20 71.0 1.8 14.9 2 2 16 18 18 18 18 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001012915.1_23529001_2 - 5.1e-152 492.3 52.6 5.6e-14 52.2 0.2 20.6 7 4 14 22 22 22 22 Ankyrin repeats (many copies) Ank PF00023.28 001012915.1_23529001_2 - 2.6e-141 454.3 76.9 4.1e-07 30.0 0.1 28.1 28 0 0 28 28 28 26 Ankyrin repeat Ank_5 PF13857.4 001012915.1_23529001_2 - 9.5e-117 378.9 66.4 7.3e-10 38.8 0.3 22.2 5 3 18 23 23 23 22 Ankyrin repeats (many copies) Ank_3 PF13606.4 001012915.1_23529001_2 - 1.8e-108 341.1 56.2 3.1e-06 27.0 0.3 28.9 29 0 0 29 29 29 23 Ankyrin repeat Ank_2 PF12796.5 204551.1_23529001_1 - 2.6e-90 297.0 18.8 9.9e-17 61.2 0.0 8.1 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.4 204551.1_23529001_1 - 1.6e-67 222.9 17.2 1.4e-10 41.3 0.1 11.0 4 2 8 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.28 204551.1_23529001_1 - 1.9e-62 205.0 20.1 5.4e-05 23.3 0.1 15.5 15 0 0 15 15 15 13 Ankyrin repeat Ank_3 PF13606.4 204551.1_23529001_1 - 3.5e-60 192.7 18.4 0.00075 19.6 0.0 15.7 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.4 204551.1_23529001_1 - 2e-58 193.3 23.1 7.5e-10 38.8 0.1 11.8 4 3 8 12 12 12 12 Ankyrin repeats (many copies) IQ PF00612.25 204551.1_23529001_1 - 4.9e-08 31.9 6.1 0.0038 16.8 0.3 3.2 2 0 0 2 2 2 2 IQ calmodulin-binding motif Ribosomal_L29 PF00831.21 203585.1_53521001_1 - 1.5e-20 72.7 2.2 1.5e-20 72.7 2.2 2.5 2 1 2 4 4 4 1 Ribosomal L29 protein Snf7 PF03357.19 200563.2_16124001_3 - 2.5e-11 43.4 14.8 4.1e-11 42.6 14.8 1.3 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.12 200563.2_16124001_3 - 0.92 9.3 8.7 2.5 7.9 8.7 1.7 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Caveolin PF01146.15 001170356.1_50022001_1 - 5e-60 201.1 0.6 6.1e-60 200.8 0.6 1.1 1 0 0 1 1 1 1 Caveolin DUF3169 PF11368.6 001170356.1_50022001_1 - 0.15 11.4 4.2 0.25 10.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Neur_chan_LBD PF02931.21 001124439.1_36925001_3 - 7.7e-70 234.6 1.9 1.1e-69 234.1 1.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001124439.1_36925001_3 - 6.2e-44 150.7 0.0 2e-43 149.0 0.0 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.30 001079324.2_53526001_2 - 4e-18 65.3 9.7 8e-05 23.2 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001079324.2_53526001_2 - 1.3e-06 28.5 0.1 0.081 13.1 0.0 4.6 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001079324.2_53526001_2 - 0.00037 19.4 0.5 0.0026 16.7 0.1 2.4 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hormone_1 PF00103.18 001200245.1_26622001_1 - 4.4e-22 78.8 4.0 8.4e-21 74.6 4.0 2.0 1 1 0 1 1 1 1 Somatotropin hormone family WD40 PF00400.30 001323501.1_23924001_2 - 6.2e-13 48.9 11.8 1.2e-05 25.8 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF1079 PF06435.9 001323501.1_23924001_2 - 0.18 11.9 2.4 0.65 10.1 2.4 2.0 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) RRM_1 PF00076.20 213214.1_16124001_2 - 9.4e-12 44.5 0.1 1.6e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.3 213214.1_16124001_2 - 1.2e-05 25.9 0.0 3.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Torus domain Nup35_RRM_2 PF14605.4 213214.1_16124001_2 - 7.4e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.3 213214.1_16124001_2 - 0.00091 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.22 213214.1_16124001_2 - 0.003 17.3 1.8 0.003 17.3 1.8 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.9 213214.1_16124001_2 - 0.011 15.6 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif zf-CCCH_2 PF14608.4 213214.1_16124001_2 - 0.018 15.4 0.5 0.018 15.4 0.5 2.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Calcipressin PF04847.10 213214.1_16124001_2 - 0.062 12.9 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Calcipressin FYVE PF01363.19 213214.1_16124001_2 - 0.75 9.8 8.4 0.057 13.4 1.6 2.5 3 0 0 3 3 3 0 FYVE zinc finger T-box PF00907.20 001085863.1_53424001_1 - 8.6e-81 270.4 0.0 1.1e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 T-box C2 PF00168.28 205171.1_23526001_3 - 4.6e-54 180.9 0.4 2.4e-26 91.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain Comm PF15957.3 205171.1_23526001_3 - 0.01 16.1 0.0 0.01 16.1 0.0 2.8 3 0 0 3 3 3 1 Commissureless CEP76-C2 PF15627.4 205171.1_23526001_3 - 0.013 14.9 0.0 2.5 7.5 0.0 2.3 1 1 1 2 2 2 0 CEP76 C2 domain DOCK-C2 PF14429.4 205171.1_23526001_3 - 0.054 13.2 0.3 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins MAP17 PF15807.3 205171.1_23526001_3 - 0.062 13.4 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.4 205171.1_23526001_3 - 0.18 12.5 0.3 0.43 11.3 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.4 205171.1_23526001_3 - 0.35 11.0 3.1 0.51 10.4 2.0 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Annexin PF00191.18 001282846.1_13323001_1 - 2.5e-79 261.1 10.9 2.3e-22 78.7 0.3 4.1 4 0 0 4 4 4 4 Annexin Phage_TAC_5 PF08890.9 001282846.1_13323001_1 - 0.11 12.5 6.5 0.48 10.3 0.4 3.1 1 1 2 3 3 3 0 Phage XkdN-like tail assembly chaperone protein, TAC Fer4_13 PF13370.4 001282846.1_13323001_1 - 0.14 12.6 1.3 0.99 9.9 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I TPR_2 PF07719.15 001282846.1_13323001_1 - 0.16 12.0 0.6 9.7 6.5 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DSPc PF00782.18 001281713.1_02223001_1 - 3e-29 101.4 0.0 3.9e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.10 001281713.1_02223001_1 - 0.0048 17.1 0.0 0.0089 16.2 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.25 001281713.1_02223001_1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPn PF14671.4 001281713.1_02223001_1 - 0.018 15.4 0.1 0.027 14.8 0.1 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Ldh_1_N PF00056.21 001287263.1_01424001_2 - 2.6e-49 166.8 0.2 3.7e-49 166.3 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001287263.1_01424001_2 - 9.7e-22 77.5 0.0 2.1e-21 76.4 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.21 001287287.1_01423001_1 - 4.1e-49 166.2 0.3 5.9e-49 165.7 0.3 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001287287.1_01423001_1 - 6.7e-21 74.8 0.0 1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.14 001287287.1_01423001_1 - 0.0007 19.1 0.2 0.0018 17.7 0.1 1.8 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase AlaDh_PNT_C PF01262.19 001287287.1_01423001_1 - 0.012 14.8 0.4 0.018 14.2 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GHBP PF12772.5 001282815.1_13325001_1 - 1.7e-131 438.1 8.1 2.1e-131 437.8 8.1 1.1 1 0 0 1 1 1 1 Growth hormone receptor binding EpoR_lig-bind PF09067.8 001282815.1_13325001_1 - 4.8e-13 49.1 2.1 4.8e-13 49.1 2.1 2.3 3 0 0 3 3 3 1 Erythropoietin receptor, ligand binding fn3 PF00041.19 001282815.1_13325001_1 - 2.5e-06 27.6 0.2 5.1e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain IL6Ra-bind PF09240.8 001282815.1_13325001_1 - 0.79 10.1 4.7 0.21 11.9 1.0 1.9 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding Gp_dh_C PF02800.18 001282835.1_13323001_1 - 9.4e-70 233.1 0.0 1.4e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001282835.1_13323001_1 - 4.6e-39 132.7 0.4 9.3e-39 131.7 0.2 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001282835.1_13323001_1 - 0.024 14.6 0.2 0.097 12.7 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus OstA PF03968.12 001282835.1_13323001_1 - 0.033 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 OstA-like protein 2-Hacid_dh_C PF02826.17 001282835.1_13323001_1 - 0.053 12.7 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ubiquitin PF00240.21 001305023.1_21523001_1 - 6.2e-20 70.6 0.0 9.6e-20 70.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 001305023.1_21523001_1 - 3.9e-09 36.1 0.0 6.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.6 001305023.1_21523001_1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF2407 PF10302.7 001305023.1_21523001_1 - 0.061 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain 7tm_1 PF00001.19 001303175.1_30824001_1 - 6.4e-78 261.6 7.2 1.1e-77 260.8 7.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001303175.1_30824001_1 - 1.8e-16 60.1 5.1 3e-16 59.5 5.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001303175.1_30824001_1 - 6.5e-07 28.8 5.8 1.6e-06 27.5 5.8 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001303175.1_30824001_1 - 1.2e-06 28.4 12.1 1.2e-05 25.1 9.0 2.4 2 1 0 2 2 2 1 Olfactory receptor DUF1180 PF06679.10 001303175.1_30824001_1 - 0.0071 16.6 0.1 0.12 12.6 0.0 2.8 4 0 0 4 4 4 1 Protein of unknown function (DUF1180) DUF1049 PF06305.9 001303175.1_30824001_1 - 0.98 9.2 3.6 1.6 8.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Asp PF00026.21 001309828.1_12823001_1 - 2.2e-121 405.0 0.0 2.6e-121 404.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001309828.1_12823001_1 - 3.5e-11 43.6 0.1 1e-09 38.7 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001309828.1_12823001_1 - 3.5e-08 33.0 0.1 6.4e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.4 001309828.1_12823001_1 - 3.9e-06 26.6 0.0 1.1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal DUF3626 PF12294.6 001309828.1_12823001_1 - 0.023 13.6 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3626) Asp_protease_2 PF13650.4 001309828.1_12823001_1 - 0.029 14.9 0.1 22 5.7 0.0 3.3 3 0 0 3 3 3 0 Aspartyl protease PRK PF00485.16 199764.2_16124001_3 - 1.2e-48 165.3 0.0 1.6e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.4 199764.2_16124001_3 - 6.8e-06 26.5 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain CoaE PF01121.18 199764.2_16124001_3 - 8.3e-06 25.4 0.1 2e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase Zeta_toxin PF06414.10 199764.2_16124001_3 - 0.00037 19.7 0.0 0.00053 19.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.4 199764.2_16124001_3 - 0.045 14.0 1.2 0.13 12.6 1.2 1.7 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.16 199764.2_16124001_3 - 0.1 12.2 0.1 3.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase LTXXQ PF07813.10 199764.2_16124001_3 - 0.15 12.6 0.1 0.26 11.9 0.1 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein Synuclein PF01387.15 001302099.1_47623001_1 - 1.7e-54 183.5 18.0 2.2e-54 183.1 18.0 1.1 1 0 0 1 1 1 1 Synuclein Gp_dh_C PF02800.18 001303179.1_30823001_1 - 7.1e-70 233.5 0.0 1.1e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001303179.1_30823001_1 - 3.8e-39 133.0 0.4 8.5e-39 131.9 0.3 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA PF03968.12 001303179.1_30823001_1 - 0.019 15.0 0.0 0.062 13.4 0.0 1.8 2 0 0 2 2 2 0 OstA-like protein DapB_N PF01113.18 001303179.1_30823001_1 - 0.079 13.0 0.4 0.42 10.6 0.2 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Reprolysin PF01421.17 001323249.1_44123001_1 - 3.7e-60 203.1 0.3 5.5e-60 202.6 0.3 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.17 001323249.1_44123001_1 - 9.4e-30 103.6 0.1 1.8e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.4 001323249.1_44123001_1 - 5.5e-23 82.0 0.0 1e-22 81.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.21 001323249.1_44123001_1 - 1e-14 54.9 25.0 1e-14 54.9 25.0 2.1 2 0 0 2 2 2 1 Disintegrin Reprolysin_4 PF13583.4 001323249.1_44123001_1 - 2.8e-14 53.1 0.0 4.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.4 001323249.1_44123001_1 - 7.4e-13 49.0 0.1 1.3e-12 48.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.4 001323249.1_44123001_1 - 2.8e-12 46.8 0.1 5.8e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.6 001323249.1_44123001_1 - 0.00084 18.9 0.4 0.0019 17.7 0.1 1.6 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.22 001323249.1_44123001_1 - 0.0017 18.1 0.5 0.003 17.3 0.5 1.6 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.7 001323249.1_44123001_1 - 0.069 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.11 001323249.1_44123001_1 - 0.095 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A CUB PF00431.18 001323497.1_23926001_1 - 3.2e-16 59.5 0.0 5.5e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.15 001323497.1_23926001_1 - 1.5e-12 47.5 12.1 3e-12 46.5 12.1 1.6 1 0 0 1 1 1 1 PDGF/VEGF domain Reprolysin PF01421.17 001323248.1_44125001_3 - 2.5e-61 206.9 2.5 3.7e-61 206.4 2.5 1.2 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.17 001323248.1_44125001_3 - 2e-28 99.2 0.1 4.3e-28 98.2 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.4 001323248.1_44125001_3 - 1.4e-19 70.9 0.5 2.6e-19 70.0 0.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.21 001323248.1_44125001_3 - 1.7e-14 54.3 25.0 1.7e-14 54.3 25.0 2.2 2 0 0 2 2 1 1 Disintegrin Reprolysin_4 PF13583.4 001323248.1_44125001_3 - 2.4e-13 50.1 0.2 4.3e-13 49.2 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.4 001323248.1_44125001_3 - 5.1e-13 49.5 0.1 8.4e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.4 001323248.1_44125001_3 - 8.8e-10 38.7 0.7 1.9e-09 37.6 0.7 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.22 001323248.1_44125001_3 - 0.0027 17.4 0.9 0.0044 16.8 0.9 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.11 001323248.1_44125001_3 - 0.0079 16.0 0.2 0.015 15.1 0.2 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M57 PF12388.6 001323248.1_44125001_3 - 0.016 14.7 0.2 0.083 12.4 0.1 2.0 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF4041 PF13250.4 001323248.1_44125001_3 - 0.035 13.9 0.1 0.08 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) Zincin_1 PF06262.9 001323248.1_44125001_3 - 0.17 11.9 0.2 0.35 10.9 0.2 1.4 1 0 0 1 1 1 0 Zinicin-like metallopeptidase Pyr_redox_2 PF07992.12 001353394.1_16129001_1 - 7.6e-57 192.6 0.1 9.4e-57 192.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.20 001353394.1_16129001_1 - 8.1e-28 96.7 0.0 1.4e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.25 001353394.1_16129001_1 - 2.2e-16 60.1 0.0 5.6e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.4 001353394.1_16129001_1 - 3.1e-08 33.1 0.9 2.5e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.22 001353394.1_16129001_1 - 1.8e-06 27.2 5.3 3.4e-05 23.0 1.8 2.2 1 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.12 001353394.1_16129001_1 - 0.0012 17.5 0.4 0.0022 16.6 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.19 001353394.1_16129001_1 - 0.0045 16.2 0.1 0.012 14.8 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.4 001353394.1_16129001_1 - 0.0052 15.8 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.20 001353394.1_16129001_1 - 0.0078 15.2 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.5 001353394.1_16129001_1 - 0.012 14.8 0.1 0.017 14.4 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.15 001353394.1_16129001_1 - 0.033 13.3 0.2 0.062 12.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.22 001353394.1_16129001_1 - 0.07 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.4 001353394.1_16129001_1 - 0.15 12.2 0.2 0.31 11.2 0.2 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Histone_H2A_C PF16211.3 001024396.1_16123001_3 - 8e-21 73.4 1.7 8e-21 73.4 1.7 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.22 001024396.1_16123001_3 - 1.9e-16 60.6 0.0 2.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001024396.1_16123001_3 - 0.00016 21.7 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Trypsin PF00089.24 001323246.1_44122001_1 - 6.5e-61 205.8 0.0 7.4e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001323246.1_44122001_1 - 5.7e-06 27.1 0.0 9.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001323246.1_44122001_1 - 0.00024 21.3 0.0 0.00042 20.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Fucose_iso_N2 PF07882.10 001323246.1_44122001_1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain AZUL PF16558.3 001323246.1_44122001_2 - 0.011 15.8 0.3 0.025 14.7 0.3 1.6 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Trypsin PF00089.24 001323247.1_44122001_1 - 1.2e-60 205.0 0.0 1.3e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001323247.1_44122001_1 - 4.8e-06 27.4 0.0 9.7e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001323247.1_44122001_1 - 0.00017 21.8 0.0 0.00037 20.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Ras PF00071.20 001303223.1_30822001_1 - 4.5e-58 195.3 0.0 5.5e-58 195.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001303223.1_30822001_1 - 2.2e-21 76.2 0.0 3.7e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001303223.1_30822001_1 - 2.5e-09 36.7 0.0 3.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001303223.1_30822001_1 - 1e-06 28.3 0.3 5.7e-06 25.9 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001303223.1_30822001_1 - 8.9e-06 25.6 0.0 0.036 13.8 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001303223.1_30822001_1 - 5.1e-05 23.2 0.1 0.0001 22.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ArgK PF03308.14 001303223.1_30822001_1 - 0.0039 16.1 0.1 0.048 12.5 0.0 2.0 2 0 0 2 2 2 1 ArgK protein G-alpha PF00503.18 001303223.1_30822001_1 - 0.0075 15.3 0.3 0.24 10.4 0.3 2.0 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.16 001303223.1_30822001_1 - 0.0086 15.5 0.0 0.054 12.9 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.15 001303223.1_30822001_1 - 0.08 12.5 0.4 1.2 8.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Cys_knot PF00007.20 001303152.1_30822001_3 - 4.9e-29 100.6 4.3 5.8e-29 100.3 4.3 1.1 1 0 0 1 1 1 1 Cystine-knot domain ATP_synt_H PF05493.11 001172635.1_16122001_3 - 5.5e-22 77.9 2.6 9e-22 77.2 2.6 1.3 1 0 0 1 1 1 1 ATP synthase subunit H SOAR PF16533.3 001278693.1_30529001_1 - 4.7e-41 138.7 3.8 4.7e-41 138.7 3.8 2.7 2 0 0 2 2 2 1 STIM1 Orai1-activating region SAM_2 PF07647.15 001278693.1_30529001_1 - 6.5e-06 26.0 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001278693.1_30529001_1 - 9.1e-05 22.7 0.3 0.00038 20.7 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ERM PF00769.17 001278693.1_30529001_1 - 2 8.0 28.5 6.1 6.5 28.5 1.8 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4446 PF14584.4 001278693.1_30529001_1 - 2.9 7.7 6.5 0.99 9.2 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) VIT1 PF01988.17 001278693.1_30529001_1 - 7.4 6.2 7.5 20 4.8 7.5 1.8 1 1 0 1 1 1 0 VIT family MITF_TFEB_C_3_N PF15951.3 001310076.1_30524001_1 - 4.8e-49 166.8 11.4 4.8e-49 166.8 11.4 2.5 2 0 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus DUF3371 PF11851.6 001310076.1_30524001_1 - 8.2e-34 117.2 4.2 8.2e-34 117.2 4.2 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3371) HLH PF00010.24 001310076.1_30524001_1 - 1.3e-16 60.2 0.5 1.3e-16 60.2 0.5 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Ilar_coat PF01787.14 001310076.1_30524001_1 - 1.1 8.9 5.0 2.2 7.9 5.0 1.4 1 0 0 1 1 1 0 Ilarvirus coat protein Ribophorin_I PF04597.12 001310076.1_30524001_1 - 1.1 8.3 4.9 1.6 7.7 4.9 1.2 1 0 0 1 1 1 0 Ribophorin I Lbh PF15317.4 001310075.1_30524001_3 - 1.2e-26 93.3 4.8 1.2e-26 93.3 4.8 1.6 2 0 0 2 2 2 1 Cardiac transcription factor regulator, Developmental protein RNase_H PF00075.22 001285799.1_30523001_3 - 2.3e-40 138.0 0.1 3.2e-40 137.5 0.1 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285799.1_30523001_3 - 1.5e-18 66.7 3.8 2.8e-18 65.8 3.8 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285799.1_30523001_3 - 2.6e-06 27.0 0.1 5.8e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like DUF846 PF05832.10 001281887.1_30523001_2 - 9.9e-55 184.3 8.2 1.3e-54 183.9 8.2 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) BTB PF00651.29 001078601.1_50025001_1 - 7.6e-27 93.6 0.4 4.8e-26 91.0 0.5 2.1 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.4 001078601.1_50025001_1 - 2.4e-24 84.5 53.8 8.8e-07 29.0 0.5 7.7 9 0 0 9 9 7 5 Zinc-finger double domain zf-C2H2 PF00096.24 001078601.1_50025001_1 - 1.2e-20 72.6 48.8 3.3e-05 24.0 0.3 7.8 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001078601.1_50025001_1 - 5.2e-14 51.6 45.7 0.00086 19.8 0.3 7.4 7 0 0 7 7 6 5 C2H2-type zinc finger zf-met PF12874.5 001078601.1_50025001_1 - 1.1e-10 41.4 30.1 0.00025 21.2 0.1 7.0 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001078601.1_50025001_1 - 6.8e-07 29.3 18.6 0.12 12.6 1.3 6.1 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding DZR PF12773.5 001078601.1_50025001_1 - 4.5e-06 26.4 21.4 0.081 12.8 2.3 4.5 4 0 0 4 4 4 4 Double zinc ribbon zf-C2HE PF16278.3 001078601.1_50025001_1 - 0.00092 19.5 36.8 0.061 13.7 0.2 7.0 1 1 5 6 6 6 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.4 001078601.1_50025001_1 - 0.0023 17.7 36.3 0.02 14.7 0.0 7.1 7 0 0 7 7 7 3 C2H2-type zinc finger DUF3342 PF11822.6 001078601.1_50025001_1 - 0.014 15.5 0.2 0.029 14.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Zn-ribbon_8 PF09723.8 001078601.1_50025001_1 - 0.022 14.7 0.9 0.022 14.7 0.9 5.7 3 2 3 6 6 6 0 Zinc ribbon domain zinc_ribbon_15 PF17032.3 001078601.1_50025001_1 - 0.049 14.3 19.8 4.3 8.0 2.2 4.5 2 1 0 4 4 4 0 zinc-ribbon family DUF3268 PF11672.6 001078601.1_50025001_1 - 0.27 11.5 12.6 1.1 9.4 0.3 4.0 3 1 1 4 4 4 0 zinc-finger-containing domain zf-C2H2_11 PF16622.3 001078601.1_50025001_1 - 0.27 10.9 0.0 0.27 10.9 0.0 6.3 8 0 0 8 8 7 0 zinc-finger C2H2-type GAGA PF09237.9 001078601.1_50025001_1 - 0.3 10.8 15.5 5.6 6.7 0.0 5.0 1 1 4 5 5 5 0 GAGA factor C1_4 PF07975.10 001078601.1_50025001_1 - 1.6 8.9 21.7 2.8 8.1 4.0 4.7 3 1 0 4 4 4 0 TFIIH C1-like domain zf-C2H2_9 PF16293.3 001078601.1_50025001_1 - 2 8.2 7.0 40 4.0 0.0 4.8 4 2 1 5 5 5 0 C2H2 type zinc-finger (1 copy) HypA PF01155.17 001078601.1_50025001_1 - 3.6 7.5 22.7 1.1 9.2 0.4 4.5 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA COE1_DBD PF16422.3 001164535.1_49924001_1 - 1.1e-142 473.1 3.4 1.1e-142 473.1 3.4 2.0 2 0 0 2 2 2 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.3 001164535.1_49924001_1 - 6.1e-34 115.3 1.8 9.4e-28 95.5 0.3 2.5 2 0 0 2 2 2 2 Transcription factor COE1 helix-loop-helix domain TIG PF01833.22 001164535.1_49924001_1 - 2.7e-12 46.4 0.1 9.8e-12 44.7 0.1 2.0 1 0 0 1 1 1 1 IPT/TIG domain Homeobox PF00046.27 001012251.1_16123001_1 - 1.3e-21 76.0 4.7 2.7e-21 75.0 4.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001012251.1_16123001_1 - 0.1 12.4 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain GSHPx PF00255.17 144467.1_16122120_2 - 4.1e-31 106.6 0.0 6e-31 106.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase EF-hand_5 PF13202.4 144467.1_16122120_2 - 0.48 9.9 1.4 2.4 7.7 0.5 2.1 2 0 0 2 2 2 0 EF hand Mit_proteolip PF08039.9 001357587.1_53529001_1 - 0.41 10.9 4.2 1.5 9.1 4.2 1.9 1 0 0 1 1 1 0 Mitochondrial proteolipid Syja_N PF02383.16 001357587.1_53529001_3 - 1.7e-92 310.0 0.6 2.2e-92 309.5 0.6 1.2 1 0 0 1 1 1 1 SacI homology domain Ribosomal_S5 PF00333.18 001200138.1_26622001_1 - 1.4e-32 111.3 0.3 2.5e-32 110.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.13 001200138.1_26622001_1 - 2.3e-28 97.4 0.0 3.9e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain zf-C4 PF00105.16 001323241.1_13924001_2 - 1.6e-28 98.8 15.8 3.1e-28 97.9 15.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001323241.1_13924001_2 - 3e-24 85.6 1.1 4.2e-24 85.2 0.1 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.3 001323241.1_13924001_2 - 0.055 13.4 2.9 0.11 12.5 2.9 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type ERbeta_N PF12497.6 001323589.1_49627001_2 - 3.5e-50 168.4 6.4 5.7e-50 167.7 6.4 1.3 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.28 001323589.1_49627001_2 - 1.1e-34 119.7 1.8 1.6e-34 119.2 1.8 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001323589.1_49627001_2 - 3.4e-31 107.4 13.4 7.5e-31 106.3 13.4 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Dynamin_M PF01031.18 001200174.1_26626001_2 - 1e-75 254.5 6.5 1.9e-75 253.6 6.5 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.21 001200174.1_26626001_2 - 1.3e-46 158.6 1.6 1.8e-46 158.1 0.1 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.16 001200174.1_26626001_2 - 1.5e-23 82.6 4.7 4.3e-23 81.1 4.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.21 001200174.1_26626001_2 - 5.8e-05 23.0 0.3 0.00031 20.7 0.3 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.25 001200174.1_26626001_2 - 0.0091 16.4 0.2 0.088 13.2 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.4 001200174.1_26626001_2 - 0.013 15.2 0.0 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.4 001200174.1_26626001_2 - 0.038 13.6 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Oest_recep PF02159.13 001279770.1_37529001_2 - 1.3e-39 135.8 7.3 6.1e-39 133.5 3.3 2.3 2 0 0 2 2 2 1 Oestrogen receptor Hormone_recep PF00104.28 001279770.1_37529001_2 - 3e-34 118.3 3.7 5.3e-34 117.5 3.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001279770.1_37529001_2 - 1.2e-30 105.6 13.9 1.2e-30 105.6 13.9 3.3 2 1 1 3 3 3 1 Zinc finger, C4 type (two domains) AP3D1 PF06375.9 001279770.1_37529001_2 - 6.8 6.8 9.0 11 6.1 9.0 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Dmrt1 PF12374.6 001286311.1_53622001_1 - 2.1e-22 79.2 8.2 2.1e-22 79.2 8.2 2.7 3 0 0 3 3 3 1 Double-sex mab3 related transcription factor 1 DM PF00751.16 001286311.1_53622001_1 - 1.1e-21 76.3 12.0 1.6e-21 75.8 10.4 2.0 2 0 0 2 2 2 1 DM DNA binding domain Anp1 PF03452.12 001286311.1_53622001_1 - 0.14 11.5 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Anp1 Zona_pellucida PF00100.21 001316908.1_53625001_1 - 2.1e-45 155.4 0.0 2.8e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.16 001316908.1_53625001_1 - 3.5e-07 29.9 7.5 3.5e-07 29.9 7.5 2.2 2 0 0 2 2 2 1 Trefoil (P-type) domain Tat PF00539.16 001316908.1_53625001_1 - 0.041 13.9 3.0 0.13 12.3 3.0 1.8 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) DUF4723 PF15851.3 001316908.1_53625001_2 - 2.7 8.1 31.0 19 5.3 1.2 6.2 1 1 6 7 7 7 0 Domain of unknown function (DUF4723) 7tm_1 PF00001.19 001316912.1_53622001_1 - 3.3e-32 111.6 39.7 3.8e-31 108.2 39.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001316912.1_53622001_1 - 7.4e-10 38.9 28.6 1.7e-07 31.2 21.2 2.9 1 1 2 3 3 3 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.7 001316912.1_53622001_1 - 4.4e-08 32.7 33.8 2.2e-07 30.4 33.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001316912.1_53622001_1 - 0.81 8.8 39.8 0.44 9.7 27.4 2.7 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Lipase_GDSL_2 PF13472.4 001316906.1_53623001_1 - 0.0031 17.8 0.0 0.0052 17.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DNA_pol_B_palm PF14792.4 001286303.1_53623001_2 - 2.6e-39 133.8 0.1 7.9e-39 132.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.4 001286303.1_53623001_2 - 3.2e-19 68.9 1.4 1.1e-17 64.1 1.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.7 001286303.1_53623001_2 - 3.3e-19 68.4 0.2 6.2e-18 64.3 0.0 2.4 1 1 1 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.4 001286303.1_53623001_2 - 4.4e-18 65.0 0.1 1.4e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_5 PF14520.4 001286303.1_53623001_2 - 9.7e-08 32.4 0.4 0.00011 22.7 0.0 2.8 3 0 0 3 3 3 2 Helix-hairpin-helix domain HHH_2 PF12826.5 001286303.1_53623001_2 - 0.0047 16.9 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif NTP_transf_2 PF01909.21 001286303.1_53623001_2 - 0.0062 16.7 0.1 0.024 14.8 0.0 2.1 1 1 1 2 2 2 1 Nucleotidyltransferase domain HHH_3 PF12836.5 001286303.1_53623001_2 - 0.015 15.4 0.2 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif Cdd1 PF11731.6 001286303.1_53623001_2 - 0.031 14.4 0.0 0.23 11.6 0.0 2.3 2 1 0 2 2 2 0 Pathogenicity locus HHH PF00633.21 001286303.1_53623001_2 - 0.052 13.3 1.7 6.8 6.6 0.3 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif DUF3701 PF12482.6 001286303.1_53623001_2 - 0.17 11.8 0.0 23 5.0 0.0 2.6 2 0 0 2 2 2 0 Phage integrase protein HSP70 PF00012.18 001316911.1_53625001_2 - 3.6e-262 870.8 7.4 4.1e-262 870.6 7.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001316911.1_53625001_2 - 7.9e-17 60.9 0.2 4.4e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.14 001316911.1_53625001_2 - 0.00099 18.8 0.0 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.4 001316911.1_53625001_2 - 0.0049 17.1 2.6 1.8 8.9 0.0 3.2 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.16 001316911.1_53625001_2 - 0.2 10.7 1.2 0.35 9.9 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase XPG_N PF00752.15 001286299.1_53623001_1 - 2.2e-36 124.3 0.0 5.1e-36 123.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.16 001286299.1_53623001_1 - 3.1e-29 101.0 0.1 8.6e-29 99.6 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.18 001286299.1_53623001_1 - 5.3e-09 36.4 0.0 4.6e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.4 001286299.1_53623001_1 - 0.0063 17.0 0.1 0.022 15.2 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain Rb_C PF08934.8 001286307.2_53627001_2 - 4.1e-75 250.5 2.0 8e-75 249.6 2.0 1.5 1 0 0 1 1 1 1 Rb C-terminal domain RB_A PF01858.15 001286307.2_53627001_2 - 1.6e-72 243.4 0.0 5.4e-72 241.7 0.0 2.0 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain RB_B PF01857.18 001286307.2_53627001_2 - 1.5e-30 105.8 6.3 1.5e-30 105.8 6.3 3.7 4 0 0 4 4 4 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.6 001286307.2_53627001_2 - 3.3e-13 49.2 4.7 3.3e-13 49.2 4.7 5.0 5 2 0 6 6 6 1 Domain of unknown function (DUF3452) FOXO_KIX_bdg PF16675.3 001286287.1_53626001_2 - 1.5e-28 98.8 7.3 1.5e-28 98.8 7.3 1.8 2 0 0 2 2 2 1 KIX-binding domain of forkhead box O, CR2 Forkhead PF00250.16 001286287.1_53626001_2 - 3.7e-25 87.9 0.1 8.3e-25 86.8 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain FOXO-TAD PF16676.3 001286287.1_53626001_2 - 8.5e-20 70.8 10.1 8.5e-20 70.8 10.1 1.9 2 0 0 2 2 2 1 Transactivation domain of FOXO protein family EGF PF00008.25 001286280.1_53622001_3 - 0.0012 19.0 5.7 0.0028 17.8 5.7 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.11 001286280.1_53622001_3 - 0.23 11.7 6.7 0.45 10.8 6.7 1.5 1 0 0 1 1 1 0 EGF-like domain HSP70 PF00012.18 001286281.1_53625001_3 - 3.6e-259 860.9 8.6 4.1e-259 860.7 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001286281.1_53625001_3 - 8.3e-17 60.9 0.3 1.8e-15 56.5 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.14 001286281.1_53625001_3 - 0.00063 19.4 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.4 001286281.1_53625001_3 - 0.0015 18.8 0.7 1.7 9.0 0.0 2.9 3 0 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.18 001286281.1_53625001_3 - 0.002 17.5 0.5 1.6 8.0 0.0 3.0 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.8 001286281.1_53625001_3 - 0.017 14.0 0.1 0.1 11.5 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain SHS2_FTSA PF02491.18 001286281.1_53625001_3 - 0.39 11.0 1.5 8.4 6.7 0.3 2.6 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA Torus PF16131.3 001286297.1_53623001_3 - 9.6e-08 32.6 19.5 0.0031 18.1 1.9 3.8 3 1 1 4 4 4 3 Torus domain zf-RING_2 PF13639.4 001286297.1_53623001_3 - 5.8e-07 29.5 5.0 5.8e-07 29.5 5.0 3.1 4 0 0 4 4 4 1 Ring finger domain zf-CCCH PF00642.22 001286297.1_53623001_3 - 2.7e-06 27.0 3.4 2.7e-06 27.0 3.4 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.23 001286297.1_53623001_3 - 4.3e-06 26.4 4.3 1.3e-05 24.8 4.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001286297.1_53623001_3 - 2.7e-05 24.2 3.6 2.7e-05 24.2 3.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-UDP PF14569.4 001286297.1_53623001_3 - 5.7e-05 23.0 2.5 0.00017 21.5 2.5 1.8 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-CCCH_3 PF15663.3 001286297.1_53623001_3 - 0.00016 21.8 3.4 0.00016 21.8 3.4 2.9 2 0 0 2 2 2 1 Zinc-finger containing family zf-RING_UBOX PF13445.4 001286297.1_53623001_3 - 0.00019 21.2 2.7 0.00041 20.2 2.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001286297.1_53623001_3 - 0.00064 19.7 3.6 0.0011 18.9 1.2 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.4 001286297.1_53623001_3 - 0.0014 18.4 3.6 0.0014 18.4 3.6 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_11 PF17123.3 001286297.1_53623001_3 - 0.0083 15.7 1.6 0.027 14.1 1.6 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-CCCH_2 PF14608.4 001286297.1_53623001_3 - 0.018 15.4 4.3 0.018 15.4 4.3 4.4 5 1 0 5 5 4 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_2 PF13923.4 001286297.1_53623001_3 - 0.085 12.6 12.1 0.24 11.1 9.5 3.1 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001286297.1_53623001_3 - 4.9 7.1 15.2 0.066 13.1 3.2 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger TIM PF00121.16 001286301.1_53622001_1 - 2.3e-86 289.0 0.1 2.6e-86 288.8 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Ribosomal_S24e PF01282.17 001286301.1_53622001_1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S24e C1-set PF07654.13 001286293.1_53622001_1 - 3.4e-23 81.8 0.1 5.1e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_II_beta PF00969.17 001286293.1_53622001_1 - 8.9e-07 28.8 0.1 1.4e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C2-set_2 PF08205.10 001286293.1_53622001_1 - 2.3e-06 27.4 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.4 001286293.1_53622001_1 - 0.015 15.8 0.1 0.03 14.8 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin domain DUF2627 PF11118.6 001286293.1_53622001_1 - 0.055 13.9 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Peptidase_C48 PF02902.17 001286305.1_53629001_1 - 4.5e-12 46.2 0.1 1.4e-11 44.6 0.0 1.8 1 1 1 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain F-box PF00646.31 001286305.1_53629001_1 - 0.02 14.7 0.0 0.079 12.7 0.0 2.1 1 0 0 1 1 1 0 F-box domain SAP PF02037.25 001286305.1_53629001_1 - 0.034 13.8 0.1 0.11 12.1 0.1 1.9 1 0 0 1 1 1 0 SAP domain PsbW PF07123.10 001286305.1_53629001_1 - 0.16 11.8 0.1 25 4.7 0.0 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) zf-Di19 PF05605.10 001286305.1_53629001_1 - 0.5 10.6 17.1 1.9 8.7 2.4 4.8 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding EGF PF00008.25 001286291.1_53625001_2 - 0.001 19.2 2.6 0.0021 18.2 2.6 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.11 001286291.1_53625001_2 - 2 8.7 4.0 4.6 7.6 4.0 1.6 1 0 0 1 1 1 0 EGF-like domain Ald_Xan_dh_C2 PF02738.16 001286285.1_53628001_1 - 2.5e-181 603.7 0.0 3.7e-181 603.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001286285.1_53628001_1 - 3.6e-46 156.9 0.0 8.1e-46 155.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.18 001286285.1_53628001_1 - 5.1e-32 109.5 0.4 1.4e-31 108.2 0.4 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.20 001286285.1_53628001_1 - 9e-32 109.6 0.1 1.6e-31 108.8 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001286285.1_53628001_1 - 1.7e-28 98.7 0.0 3.6e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001286285.1_53628001_1 - 8.3e-09 35.1 0.2 8.3e-09 35.1 0.2 2.6 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain TIM PF00121.16 001286295.1_53622001_3 - 9.8e-86 286.9 0.0 1.1e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase FA_hydroxylase PF04116.11 001082924.1_16122001_3 - 3e-22 79.3 17.6 7e-22 78.1 17.6 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Ras PF00071.20 001089562.2_16123001_2 - 6.2e-66 220.9 0.7 8e-66 220.5 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001089562.2_16123001_2 - 1.5e-33 115.4 0.2 2.6e-33 114.7 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001089562.2_16123001_2 - 1.3e-16 60.4 0.4 1.8e-16 60.0 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001089562.2_16123001_2 - 2.5e-05 23.6 0.2 3.4e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001089562.2_16123001_2 - 0.00017 20.9 0.3 0.00025 20.4 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001089562.2_16123001_2 - 0.0091 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001089562.2_16123001_2 - 0.0094 15.4 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001089562.2_16123001_2 - 0.036 13.8 0.2 9.9 5.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF3963 PF13124.4 001089562.2_16123001_2 - 0.047 13.5 0.8 0.11 12.3 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) zf-C4 PF00105.16 001287278.1_01423001_2 - 9.8e-30 102.7 17.9 1.9e-29 101.8 17.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001287278.1_01423001_2 - 1.8e-18 66.8 0.0 4.6e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DUF3921 PF13060.4 001287278.1_01423001_2 - 0.17 11.8 0.1 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) BK_channel_a PF03493.16 204224.1_23528001_1 - 3.9e-32 110.3 0.1 9.9e-32 109.0 0.1 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.29 204224.1_23528001_1 - 5.9e-18 64.8 19.6 1.4e-17 63.6 19.6 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.14 204224.1_23528001_1 - 3e-14 52.6 3.6 3e-14 52.6 3.6 2.6 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.16 204224.1_23528001_1 - 2.6e-05 24.3 0.1 0.00017 21.7 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain Lig_chan PF00060.24 204224.1_23528001_1 - 0.05 13.3 3.7 0.27 10.9 1.0 2.7 2 0 0 2 2 2 0 Ligand-gated ion channel SR-25 PF10500.7 204224.1_23528001_1 - 6.4 6.2 13.0 12 5.3 13.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein P53 PF00870.16 001286289.1_53624001_1 - 1.9e-101 337.6 0.4 2.6e-101 337.1 0.4 1.2 1 0 0 1 1 1 1 P53 DNA-binding domain P53_TAD PF08563.9 001286289.1_53624001_1 - 5.6e-13 47.8 1.5 1.2e-12 46.7 1.5 1.6 1 0 0 1 1 1 1 P53 transactivation motif P53_tetramer PF07710.9 001286289.1_53624001_1 - 1.6e-11 43.2 0.5 4.2e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 P53 tetramerisation motif 7tm_1 PF00001.19 001312652.1_43024001_3 - 9.6e-43 146.2 9.6 1.3e-42 145.8 9.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.7 001312652.1_43024001_3 - 1.1e-19 69.8 7.3 2.5e-19 68.7 7.3 1.7 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srv PF10323.7 001312652.1_43024001_3 - 2.4e-08 33.5 13.1 4.2e-08 32.8 13.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.7 001312652.1_43024001_3 - 6.5e-08 32.1 11.8 1e-07 31.5 11.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001312652.1_43024001_3 - 0.00053 19.2 12.5 0.001 18.3 12.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001312652.1_43024001_3 - 0.18 11.4 12.0 1.1 8.8 12.0 2.0 1 1 0 1 1 1 0 Olfactory receptor Homeobox PF00046.27 131530.2_16123001_3 - 1.9e-20 72.3 7.5 3.2e-20 71.6 7.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 131530.2_16123001_3 - 0.21 11.4 1.1 0.45 10.3 1.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain IFN-gamma PF00714.15 001360715.1_05922001_3 - 0.031 14.0 0.0 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Interferon gamma IFN-gamma PF00714.15 001360732.1_32522001_1 - 0.07 12.8 0.1 0.72 9.6 0.1 2.0 2 0 0 2 2 2 0 Interferon gamma IFN-gamma PF00714.15 001360737.1_53624001_3 - 0.0023 17.6 0.3 1.8 8.3 0.1 2.2 2 0 0 2 2 2 2 Interferon gamma QueC PF06508.11 001360726.1_26022001_1 - 0.25 10.7 1.3 0.37 10.1 1.3 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC IFN-gamma PF00714.15 001360739.1_42822001_1 - 0.00015 21.5 0.7 0.063 13.0 0.2 2.1 2 0 0 2 2 2 2 Interferon gamma IFN-gamma PF00714.15 001360736.1_23124001_2 - 0.054 13.2 0.5 0.15 11.8 0.2 1.8 2 0 0 2 2 2 0 Interferon gamma IFN-gamma PF00714.15 001360735.1_35922001_2 - 0.006 16.3 0.1 2.7 7.7 0.0 2.2 2 0 0 2 2 2 2 Interferon gamma IFN-gamma PF00714.15 001360740.1_42722001_3 - 0.00027 20.7 0.7 0.088 12.5 0.2 2.2 2 0 0 2 2 2 2 Interferon gamma IFN-gamma PF00714.15 001360738.1_42922001_1 - 0.00015 21.5 0.7 0.063 13.0 0.2 2.1 2 0 0 2 2 2 2 Interferon gamma AAA_18 PF13238.4 102288.1_16124120_1 - 7.9e-06 26.3 0.0 1.1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 102288.1_16124120_2 - 0.0069 16.8 0.1 0.0097 16.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.21 102288.1_16124120_2 - 0.1 12.6 0.7 0.16 12.0 0.1 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.4 102288.1_16124120_2 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.20 132430.1_16123120_2 - 6.1e-22 77.1 0.0 9e-22 76.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 132430.1_16123120_2 - 0.0041 16.9 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Presenilin PF01080.15 132430.1_16123120_2 - 2.7 6.5 10.0 3.9 6.0 10.0 1.2 1 0 0 1 1 1 0 Presenilin Interfer-bind PF09294.8 001360774.1_48123001_2 - 2.9e-08 33.8 1.1 5.7e-08 32.9 1.1 1.5 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001360774.1_48123001_2 - 2.4e-06 27.2 0.1 5.4e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 Tissue factor fn3 PF00041.19 001360774.1_48123001_2 - 0.0017 18.5 1.2 0.64 10.3 0.1 2.6 2 1 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.15 001360765.1_27725001_1 - 1.5e-12 47.2 3.1 1.5e-12 47.2 3.1 2.4 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.8 001360765.1_27725001_1 - 9.3e-05 22.6 0.1 9.3e-05 22.6 0.1 2.5 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III DUF912 PF06024.10 001360765.1_27725001_1 - 0.02 15.0 0.1 0.05 13.8 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) fn3 PF00041.19 001360765.1_27725001_1 - 0.091 13.0 3.5 3.4 8.0 1.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain Interfer-bind PF09294.8 001360769.1_16025001_3 - 6.9e-07 29.4 1.4 1.3e-06 28.5 1.4 1.5 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001360769.1_16025001_3 - 1.9e-05 24.3 0.1 0.00095 18.8 0.0 3.0 3 0 0 3 3 3 1 Tissue factor fn3 PF00041.19 001360769.1_16025001_3 - 0.011 15.9 0.7 5 7.4 0.1 2.4 2 0 0 2 2 2 0 Fibronectin type III domain Interfer-bind PF09294.8 001360757.1_42723001_3 - 7e-09 35.8 0.1 1.7e-07 31.4 0.2 2.3 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001360757.1_42723001_3 - 8.4e-07 28.6 0.9 2e-06 27.4 0.9 1.6 1 0 0 1 1 1 1 Tissue factor fn3 PF00041.19 001360757.1_42723001_3 - 0.057 13.6 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Fibronectin type III domain Interfer-bind PF09294.8 001360771.1_48223001_3 - 3.2e-07 30.5 2.1 3.8e-07 30.2 0.7 1.9 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001360771.1_48223001_3 - 1.8e-05 24.4 0.9 0.00051 19.7 0.0 3.2 4 0 0 4 4 4 1 Tissue factor Tissue_fac PF01108.15 001360759.1_27424001_1 - 1.6e-14 53.5 0.3 3.9e-14 52.2 0.3 1.6 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001360759.1_27424001_1 - 0.00083 19.5 1.1 0.001 19.2 0.0 1.7 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.19 001360759.1_27424001_1 - 0.01 16.1 1.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.15 001360802.1_40524001_2 - 9.5e-13 47.8 0.6 1.9e-12 46.8 0.6 1.5 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001360802.1_40524001_2 - 1.2e-07 31.8 0.3 1.2e-07 31.8 0.3 1.9 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.19 001360802.1_40524001_2 - 7.5e-05 22.9 0.8 0.27 11.5 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.15 001360786.1_26024001_1 - 2.3e-11 43.3 0.2 4e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001360786.1_26024001_1 - 0.055 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001360795.1_35923001_1 - 1.2e-07 31.3 0.2 2.3e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001360795.1_35923001_1 - 0.00078 19.6 0.0 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Interfer-bind PF09294.8 001360797.1_42823001_2 - 2e-09 37.6 0.1 3.2e-08 33.7 0.1 2.3 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001360797.1_42823001_2 - 3.1e-07 30.0 0.7 6.8e-07 28.9 0.7 1.6 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360788.1_32524001_2 - 1.5e-10 40.7 0.2 3.1e-10 39.7 0.2 1.6 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001360788.1_32524001_2 - 2.5e-06 27.6 0.9 1.8e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III DUF3377 PF11857.6 001360788.1_32524001_2 - 2.8e-05 23.8 0.3 6.3e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) SKG6 PF08693.8 001360788.1_32524001_2 - 0.0032 16.7 0.1 0.0091 15.3 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain fn3 PF00041.19 001360788.1_32524001_2 - 0.0054 16.9 0.2 1.6 9.0 0.0 2.6 2 0 0 2 2 2 1 Fibronectin type III domain TMEM154 PF15102.4 001360788.1_32524001_2 - 0.011 15.5 0.2 0.022 14.5 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF912 PF06024.10 001360788.1_32524001_2 - 0.11 12.6 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3827 PF12877.5 001360788.1_32524001_2 - 0.16 10.2 0.1 0.23 9.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Tissue_fac PF01108.15 001360796.1_00326001_2 - 9.8e-13 47.7 1.0 1.8e-12 46.9 0.4 1.8 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.8 001360796.1_00326001_2 - 2e-05 24.7 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.19 001360796.1_00326001_2 - 0.0024 18.1 0.4 2.7 8.3 0.0 2.3 2 0 0 2 2 2 2 Fibronectin type III domain Interfer-bind PF09294.8 001360799.1_53625001_1 - 4.1e-10 39.8 0.0 7.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001360799.1_53625001_1 - 4.6e-07 29.5 0.1 1.2e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001360785.1_45127001_3 - 1.2e-08 35.1 0.0 3e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001360785.1_45127001_3 - 0.00024 20.7 0.8 0.00062 19.4 0.8 1.7 1 1 0 1 1 1 1 Tissue factor fn3 PF00041.19 001360785.1_45127001_3 - 0.00074 19.7 0.3 1.1 9.5 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.15 001360839.1_43029001_2 - 0.00023 20.8 0.0 0.00067 19.3 0.0 1.8 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360821.1_04129001_1 - 3.3e-06 26.7 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360832.1_15929001_3 - 8.9e-09 35.0 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360828.1_35926001_3 - 0.00027 20.6 0.0 0.00071 19.2 0.0 1.6 1 1 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360815.1_45128001_3 - 6.4e-06 25.8 0.1 2e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001360806.1_04123001_3 - 1.8e-07 31.3 0.0 3.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001360806.1_04123001_3 - 6.3e-07 29.1 0.1 1.2e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Tissue factor fn3 PF00041.19 001360806.1_04123001_3 - 0.00041 20.5 0.6 0.7 10.1 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.15 001360841.1_27624001_1 - 0.03 14.0 0.2 0.1 12.3 0.0 2.0 2 1 0 2 2 2 0 Tissue factor TMEM154 PF15102.4 001360841.1_27624001_1 - 0.077 12.8 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.8 001360841.1_27624001_1 - 0.78 9.1 7.9 1.8 7.9 7.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Tissue_fac PF01108.15 001360835.1_49228001_2 - 0.0015 18.2 0.0 0.0039 16.8 0.0 1.7 1 0 0 1 1 1 1 Tissue factor SKG6 PF08693.8 001360835.1_49228001_2 - 0.15 11.4 2.1 0.31 10.4 2.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Tissue_fac PF01108.15 001360836.1_49227001_3 - 6.8e-10 38.6 0.2 1.5e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360851.1_45027001_3 - 1.4e-06 28.0 0.1 3.7e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360826.1_26023001_1 - 0.0088 15.7 0.0 0.064 13.0 0.0 2.2 2 1 0 2 2 2 1 Tissue factor Phage_holin_3_6 PF07332.9 001360826.1_26023001_1 - 0.26 11.2 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Tissue_fac PF01108.15 001360846.1_30527001_3 - 1e-07 31.6 1.7 2e-07 30.6 0.3 2.3 2 1 0 2 2 2 1 Tissue factor Tissue_fac PF01108.15 001360852.1_45027001_1 - 0.02 14.6 4.9 0.029 14.1 0.3 2.7 2 1 0 2 2 2 0 Tissue factor Tissue_fac PF01108.15 001360880.1_28127001_3 - 3.4e-14 52.4 0.8 7.5e-14 51.3 0.8 1.6 1 0 0 1 1 1 1 Tissue factor DUF4750 PF15938.3 001360880.1_28127001_3 - 0.36 10.4 7.7 0.74 9.4 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) Tissue_fac PF01108.15 001360848.1_30527001_3 - 0.038 13.7 0.3 0.038 13.7 0.3 2.7 2 1 0 2 2 2 0 Tissue factor Tissue_fac PF01108.15 001360892.1_48124001_2 - 2.3e-10 40.1 1.2 1.1e-08 34.6 0.2 2.4 2 0 0 2 2 2 1 Tissue factor fn3 PF00041.19 001360892.1_48124001_2 - 0.047 13.9 0.5 0.1 12.8 0.3 1.7 2 0 0 2 2 2 0 Fibronectin type III domain Interfer-bind PF09294.8 001360892.1_48124001_2 - 0.13 12.5 1.2 0.98 9.6 0.0 2.4 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF2284 PF10050.7 001360892.1_48124001_2 - 1.5 8.4 7.1 4.7 6.8 1.0 2.5 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) Tissue_fac PF01108.15 001360866.1_42726001_3 - 3e-06 26.9 0.0 6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360870.1_27426001_3 - 1.6e-05 24.6 0.1 4.6e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360893.1_48124001_2 - 0.00035 20.2 0.9 0.0012 18.5 0.1 2.0 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.8 001360893.1_48124001_2 - 0.0018 18.5 0.1 0.0044 17.2 0.1 1.7 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III ATP1G1_PLM_MAT8 PF02038.14 001360893.1_48124001_2 - 0.031 13.5 0.3 0.077 12.2 0.3 1.6 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family fn3 PF00041.19 001360893.1_48124001_2 - 0.035 14.3 0.2 0.076 13.2 0.2 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Tissue_fac PF01108.15 001360861.1_45127001_2 - 2.1e-05 24.2 0.0 4.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Tissue factor fn3 PF00041.19 001360861.1_45127001_2 - 0.00096 19.3 0.3 0.002 18.3 0.3 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Tissue_fac PF01108.15 001360877.1_04525001_3 - 1.2e-08 34.5 4.2 2.3e-06 27.2 0.4 2.4 2 0 0 2 2 2 2 Tissue factor Ninjurin PF04923.10 001360877.1_04525001_3 - 0.032 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Ninjurin Tissue_fac PF01108.15 001360864.1_04124001_2 - 0.013 15.1 0.2 0.026 14.2 0.2 1.4 1 0 0 1 1 1 0 Tissue factor Tissue_fac PF01108.15 001360908.1_48324001_2 - 6.8e-10 38.6 2.3 2.1e-08 33.8 0.1 2.4 2 0 0 2 2 2 2 Tissue factor Interfer-bind PF09294.8 001360908.1_48324001_2 - 0.015 15.5 1.1 0.069 13.3 0.1 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.19 001360908.1_48324001_2 - 0.04 14.1 0.2 0.097 12.9 0.2 1.7 2 0 0 2 2 2 0 Fibronectin type III domain adh_short_C2 PF13561.4 001094273.1_53423001_3 - 1e-67 228.0 0.1 1.2e-67 227.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001094273.1_53423001_3 - 5.3e-55 185.8 0.1 7e-55 185.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001094273.1_53423001_3 - 3.7e-13 49.6 0.1 5.7e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Tissue_fac PF01108.15 001360865.1_35923001_1 - 2.9e-06 26.9 0.5 5.7e-06 26.0 0.5 1.4 1 0 0 1 1 1 1 Tissue factor DUF4201 PF13870.4 001360865.1_35923001_1 - 0.0021 17.6 2.7 0.0034 16.9 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) TelA PF05816.9 001360865.1_35923001_1 - 0.006 15.6 1.0 0.0089 15.0 1.0 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) KfrA_N PF11740.6 001360865.1_35923001_1 - 0.0063 17.1 5.5 0.011 16.3 5.5 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term GAPT PF11770.6 001360865.1_35923001_1 - 0.0083 15.9 1.2 0.015 15.0 0.6 1.7 1 1 0 1 1 1 1 GRB2-binding adapter (GAPT) Jnk-SapK_ap_N PF09744.7 001360865.1_35923001_1 - 0.011 15.8 5.8 0.019 15.1 5.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMEM190 PF15431.4 001360865.1_35923001_1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 190 APG6 PF04111.10 001360865.1_35923001_1 - 0.019 14.2 5.4 0.028 13.7 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4140 PF13600.4 001360865.1_35923001_1 - 0.029 14.7 0.8 0.086 13.2 0.8 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FadA PF09403.8 001360865.1_35923001_1 - 0.033 14.5 0.8 0.058 13.7 0.8 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Spc7 PF08317.9 001360865.1_35923001_1 - 0.034 12.9 5.0 0.064 12.0 5.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein HemX PF04375.12 001360865.1_35923001_1 - 0.045 12.9 5.9 0.072 12.2 5.9 1.4 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fmp27_WPPW PF10359.7 001360865.1_35923001_1 - 0.057 12.1 4.7 0.083 11.6 4.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3450 PF11932.6 001360865.1_35923001_1 - 0.065 12.4 4.9 0.1 11.7 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LAM_C PF12544.6 001360865.1_35923001_1 - 0.069 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Exonuc_VII_L PF02601.13 001360865.1_35923001_1 - 0.079 12.4 1.8 0.13 11.7 1.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.12 001360865.1_35923001_1 - 0.1 12.5 5.5 0.16 11.8 5.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DASH_Spc34 PF08657.8 001360865.1_35923001_1 - 0.12 12.1 5.4 0.19 11.5 5.4 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 M PF02370.14 001360865.1_35923001_1 - 0.13 12.8 17.5 0.77 10.4 6.0 2.7 1 1 2 3 3 3 0 M protein repeat Serine_rich PF08824.8 001360865.1_35923001_1 - 0.15 11.9 4.0 0.35 10.7 4.0 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF3287 PF11690.6 001360865.1_35923001_1 - 0.24 11.0 4.7 0.66 9.6 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) DUF3552 PF12072.6 001360865.1_35923001_1 - 0.38 10.0 8.4 0.62 9.3 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) MctB PF11382.6 001360865.1_35923001_1 - 0.43 10.1 3.1 0.64 9.5 3.1 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB YlqD PF11068.6 001360865.1_35923001_1 - 0.47 10.7 10.2 1 9.6 10.2 1.5 1 0 0 1 1 1 0 YlqD protein bZIP_1 PF00170.19 001360865.1_35923001_1 - 0.79 9.7 4.0 1.6 8.7 4.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor Spc24 PF08286.9 001360865.1_35923001_1 - 1 9.5 9.5 1.9 8.7 9.5 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Prefoldin PF02996.15 001360865.1_35923001_1 - 1.7 8.4 7.1 2.9 7.7 7.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit IncA PF04156.12 001360865.1_35923001_1 - 4 7.0 17.8 14 5.3 17.8 1.9 1 1 0 1 1 1 0 IncA protein DivIC PF04977.13 001360865.1_35923001_1 - 6 6.6 8.3 18 5.1 8.3 1.8 1 0 0 1 1 1 0 Septum formation initiator Herpes_BLLF1 PF05109.11 001360865.1_35923001_3 - 0.93 7.2 7.5 1.3 6.8 7.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Tissue_fac PF01108.15 001360905.1_48123001_2 - 2.6e-09 36.7 0.1 4.6e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Tissue factor DUF4793 PF16041.3 001360905.1_48123001_2 - 0.5 10.5 4.8 1.6 8.9 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4793) Tissue_fac PF01108.15 001360901.1_48126001_2 - 5.9e-10 38.8 0.1 1e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001360904.1_48123001_1 - 7.9e-09 35.2 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Tissue factor DUF4793 PF16041.3 001360904.1_48123001_1 - 0.0075 16.3 6.2 0.083 13.0 0.8 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4793) BtpA PF03437.13 001016400.2_53523001_1 - 6.1e-65 219.0 0.3 7.3e-65 218.8 0.3 1.0 1 0 0 1 1 1 1 BtpA family His_biosynth PF00977.19 001016400.2_53523001_1 - 0.043 13.1 0.0 0.14 11.5 0.0 1.7 1 1 0 2 2 2 0 Histidine biosynthesis protein Tissue_fac PF01108.15 001360911.1_48325001_1 - 7.9e-09 35.2 0.2 7.9e-09 35.2 0.2 2.0 2 0 0 2 2 2 1 Tissue factor Tissue_fac PF01108.15 001360902.1_48125001_2 - 3.1e-10 39.7 0.2 8.1e-10 38.3 0.2 1.7 1 0 0 1 1 1 1 Tissue factor 7tm_1 PF00001.19 001285977.1_45022001_1 - 2e-10 40.2 8.0 3e-10 39.7 8.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.11 001285977.1_45022001_1 - 1.2e-08 34.3 23.0 7.3e-05 21.9 4.5 2.1 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001286735.1_27822001_1 - 4.6e-39 134.1 15.9 4.6e-39 134.1 15.9 1.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.19 001286738.1_27823001_1 - 2.3e-52 177.7 19.2 2.3e-52 177.7 19.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.6 001286738.1_27823001_1 - 0.14 11.8 15.7 0.31 10.7 15.7 1.6 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Sigma_reg_N PF13800.4 001286738.1_27823001_1 - 2.2 8.5 8.4 1.5 9.0 0.5 3.6 4 0 0 4 4 4 0 Sigma factor regulator N-terminal FA_desaturase PF00487.22 001286738.1_27823001_1 - 3.4 7.3 8.9 0.087 12.5 1.3 2.1 1 1 1 2 2 2 0 Fatty acid desaturase 7tm_1 PF00001.19 001286736.1_27823001_1 - 4.5e-52 176.8 22.3 6.9e-52 176.2 22.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.6 001286736.1_27823001_1 - 0.88 9.2 14.5 17 5.0 13.9 2.3 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 RNase_H PF00075.22 001285934.1_30923001_1 - 1e-45 155.3 0.0 1.7e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285934.1_30923001_1 - 1.6e-19 69.8 3.2 3.4e-19 68.7 3.2 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285934.1_30923001_1 - 0.00013 21.5 0.0 0.00032 20.2 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like 7tm_1 PF00001.19 001287403.1_25024001_2 - 1.3e-32 113.0 38.4 5.3e-32 111.0 38.4 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001287403.1_25024001_2 - 1.3e-10 41.3 25.4 1.3e-08 34.8 18.1 2.8 1 1 2 3 3 3 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.7 001287403.1_25024001_2 - 1.1e-07 31.4 33.1 3e-07 30.0 33.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.19 001287867.1_45022001_1 - 6.4e-14 51.7 9.5 9.1e-14 51.2 9.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.11 001287867.1_45022001_1 - 1.4e-12 47.2 10.2 1.9e-12 46.8 10.2 1.2 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001287867.1_45022001_1 - 0.014 14.9 11.1 0.031 13.8 11.2 1.5 1 1 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001289977.1_34723001_3 - 1.5e-37 129.1 10.3 2e-37 128.8 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.7 001289977.1_34723001_3 - 1.2e-25 88.9 2.6 2.5e-25 87.8 2.6 1.6 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.7 001289977.1_34723001_3 - 2.9e-08 33.2 8.6 7.1e-08 32.0 8.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.7 001289977.1_34723001_3 - 0.00015 21.1 14.4 0.00023 20.5 14.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001289977.1_34723001_3 - 0.0002 21.0 6.7 0.11 12.1 1.6 2.1 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srv PF10323.7 001289977.1_34723001_3 - 0.00035 19.9 8.7 0.00035 19.9 8.7 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF4079 PF13301.4 001289977.1_34723001_3 - 0.47 10.5 9.3 4.1 7.4 4.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) TAS2R PF05296.11 001289977.1_34723001_3 - 1.1 8.2 11.1 1.1 8.1 1.5 2.1 2 0 0 2 2 2 0 Taste receptor protein (TAS2R) IRK PF01007.18 001290045.1_34723001_1 - 9.3e-86 287.6 0.0 1.1e-85 287.4 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.14 001290045.1_34723001_1 - 0.00017 21.4 3.8 0.00038 20.2 3.8 1.7 1 1 0 1 1 1 1 Ion channel Homeobox PF00046.27 130934.1_16122001_1 - 1.2e-20 72.9 4.6 1.8e-20 72.3 4.6 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 130934.1_16122001_1 - 0.0037 17.0 0.2 0.0076 16.0 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Clathrin PF00637.18 001104819.1_39127001_1 - 3.6e-17 62.4 10.3 4.7e-13 49.1 2.0 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.6 001104819.1_39127001_1 - 8.8e-16 57.7 1.0 2.2e-15 56.4 1.0 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.4 001104819.1_39127001_1 - 4.7e-07 29.4 9.6 1.5e-06 27.8 9.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001104819.1_39127001_1 - 1.2e-05 25.3 7.7 3.5e-05 23.9 7.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3H2C3 PF17122.3 001104819.1_39127001_1 - 2.4e-05 24.1 10.2 6.3e-05 22.8 10.2 1.8 1 0 0 1 1 1 1 Zinc-finger zf-RING_2 PF13639.4 001104819.1_39127001_1 - 5.1e-05 23.3 9.5 5.1e-05 23.3 9.5 2.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.4 001104819.1_39127001_1 - 0.0027 17.5 9.5 0.008 16.0 9.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 001104819.1_39127001_1 - 0.0038 17.1 2.2 0.012 15.5 2.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.23 001104819.1_39127001_1 - 0.004 16.9 9.8 0.012 15.3 9.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.9 001104819.1_39127001_1 - 0.11 12.7 6.8 0.36 11.0 6.8 2.0 1 0 0 1 1 1 0 RING-like domain WD40 PF00400.30 001104819.1_39127001_1 - 0.16 12.8 0.5 14 6.6 0.0 3.6 4 0 0 4 4 3 0 WD domain, G-beta repeat zf-C3HC4_3 PF13920.4 001104819.1_39127001_1 - 0.22 11.3 6.1 0.55 10.0 6.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001104819.1_39127001_1 - 0.29 11.0 9.5 1.4 8.9 9.5 2.2 1 0 0 1 1 1 0 RING-type zinc-finger DivIC PF04977.13 001104819.1_39127001_1 - 0.37 10.5 2.3 0.87 9.3 2.3 1.6 1 0 0 1 1 1 0 Septum formation initiator zf-Nse PF11789.6 001104819.1_39127001_1 - 1.7 8.4 6.5 5.4 6.8 6.5 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.3 001104819.1_39127001_1 - 2 8.0 5.5 4.7 6.8 5.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type WD40 PF00400.30 001104853.1_39124001_2 - 9.8e-42 140.0 20.5 3.1e-08 34.0 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001104853.1_39124001_2 - 2e-14 53.5 0.0 0.00069 19.7 0.0 5.5 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.3 001104853.1_39124001_2 - 9.4e-05 21.7 0.0 0.017 14.4 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain eIF2A PF08662.9 001104853.1_39124001_2 - 0.00017 21.4 0.0 0.5 10.1 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Myc-LZ PF02344.13 001104853.1_39124001_2 - 0.05 13.6 2.4 0.11 12.4 2.4 1.6 1 0 0 1 1 1 0 Myc leucine zipper domain CALM_bind PF16025.3 001104853.1_39124001_2 - 0.097 13.0 1.7 0.18 12.1 1.7 1.3 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding DUF4407 PF14362.4 001104853.1_39124001_2 - 0.42 9.8 4.0 0.61 9.3 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TNFR_c6 PF00020.16 001160435.1_39122001_1 - 3.8e-07 30.3 41.3 5.4e-05 23.4 1.5 4.8 3 1 0 4 4 4 4 TNFR/NGFR cysteine-rich region ECSCR PF15820.3 001160435.1_39122001_1 - 0.1 12.3 0.2 0.1 12.3 0.2 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF410 PF04190.11 001104911.1_39122001_3 - 1.2e-78 264.4 0.2 1.4e-78 264.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Vps39_1 PF10366.7 001104911.1_39122001_3 - 0.017 15.2 1.1 0.12 12.6 0.1 2.5 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.15 001104911.1_39122001_3 - 0.21 11.7 1.6 4 7.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad60-SLD PF11976.6 001172045.1_39121001_1 - 3.1e-20 71.6 0.4 3.9e-20 71.3 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.21 001172045.1_39121001_1 - 1.3e-16 60.0 1.0 1.8e-16 59.5 1.0 1.2 1 0 0 1 1 1 1 Ubiquitin family p450 PF00067.20 001105095.1_39125001_1 - 2.1e-117 392.6 1.1 2.5e-117 392.3 1.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Synuclein PF01387.15 001305408.1_39121001_1 - 4.7e-43 146.4 17.6 5.4e-43 146.3 17.6 1.0 1 0 0 1 1 1 1 Synuclein YtxH PF12732.5 001305408.1_39121001_1 - 0.048 14.1 2.2 0.19 12.2 0.2 2.0 2 0 0 2 2 2 0 YtxH-like protein HSP70 PF00012.18 001104800.1_39125001_2 - 1e-248 826.3 10.3 1.2e-248 826.1 10.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001104800.1_39125001_2 - 1.3e-17 63.5 0.3 3.6e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.4 001104800.1_39125001_2 - 0.00077 19.7 1.6 4.9 7.5 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.18 001104800.1_39125001_2 - 0.0019 17.6 0.2 0.48 9.7 0.0 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.14 001104800.1_39125001_2 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.8 001104800.1_39125001_2 - 0.05 12.5 0.1 0.22 10.4 0.1 1.9 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Tissue_fac PF01108.15 001360952.1_32523001_3 - 2.1e-10 40.3 0.5 4.8e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Tissue factor DUF912 PF06024.10 001360952.1_32523001_3 - 0.072 13.3 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3377 PF11857.6 001360952.1_32523001_3 - 0.074 12.8 4.0 0.15 11.8 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Tissue_fac PF01108.15 001360871.1_27424001_1 - 0.00024 20.7 0.4 0.00074 19.2 0.1 2.0 2 0 0 2 2 2 1 Tissue factor Tissue_fac PF01108.15 001360872.1_27424001_1 - 0.00026 20.7 0.4 0.00072 19.2 0.1 1.9 2 0 0 2 2 2 1 Tissue factor GLTP PF08718.9 001360712.1_16022001_2 - 8.7e-05 22.7 4.1 0.013 15.7 0.9 2.2 1 1 1 2 2 2 2 Glycolipid transfer protein (GLTP) HBM PF16591.3 001360712.1_16022001_2 - 0.029 13.7 1.5 0.037 13.3 0.4 1.6 1 1 1 2 2 2 0 Helical bimodular sensor domain CorA PF01544.16 001360712.1_16022001_2 - 0.19 10.9 2.3 0.58 9.3 2.1 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein PhageP22-tail PF09251.8 001360712.1_16022001_2 - 0.2 9.9 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike IncA PF04156.12 001360712.1_16022001_2 - 5.3 6.7 9.0 23 4.6 9.0 1.9 1 1 0 1 1 1 0 IncA protein Tissue_fac PF01108.15 001360761.1_30523001_3 - 4.8e-13 48.7 0.0 1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001360761.1_30523001_3 - 0.00034 20.7 0.0 0.0013 18.9 0.0 1.9 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.19 001360761.1_30523001_3 - 0.027 14.7 0.3 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Fibronectin type III domain DUF3329 PF11808.6 001360761.1_30523001_3 - 0.092 13.0 0.0 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Golgin_A5 PF09787.7 001360734.1_27722001_2 - 0.0028 17.0 0.1 0.0037 16.6 0.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 AAA_18 PF13238.4 001360734.1_27722001_2 - 0.12 12.8 0.6 0.3 11.4 0.6 1.6 2 0 0 2 2 2 0 AAA domain ODC_AZ PF02100.15 001290488.2_12022001_1 - 2.5e-12 46.7 0.0 3.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme p450 PF00067.20 001282243.1_12025001_3 - 1.4e-99 333.8 0.2 1.9e-99 333.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Orn_Arg_deC_N PF02784.14 001293746.1_12024001_2 - 1.9e-75 253.3 0.0 2.4e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293746.1_12024001_2 - 5.8e-30 103.5 0.0 1e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293746.1_12024001_2 - 3.2e-05 23.3 0.0 5.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel LRR_8 PF13855.4 001328253.1_15726001_3 - 1.1e-41 140.2 28.1 4.3e-15 55.1 2.2 5.4 1 1 4 5 5 5 5 Leucine rich repeat 7tm_1 PF00001.19 001328253.1_15726001_3 - 7.4e-19 67.9 10.0 7.4e-19 67.9 10.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.5 001328253.1_15726001_3 - 1.9e-15 56.5 25.7 4.6e-05 23.5 1.2 6.1 1 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001328253.1_15726001_3 - 5.2e-14 52.2 2.0 1.6e-05 24.7 0.9 2.9 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001328253.1_15726001_3 - 2.1e-10 40.3 10.3 0.0003 20.2 0.0 3.4 1 1 2 3 3 3 3 Leucine-rich repeat Ldl_recept_a PF00057.16 001328253.1_15726001_3 - 5e-08 32.9 2.5 5e-08 32.9 2.5 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRR_1 PF00560.31 001328253.1_15726001_3 - 0.0033 17.5 29.4 0.095 13.1 0.3 8.2 7 1 0 7 7 7 2 Leucine Rich Repeat Gastrin PF00918.15 001032539.1_12422001_2 - 1.6e-24 87.1 0.6 4.6e-24 85.7 0.6 1.7 1 1 0 1 1 1 1 Gastrin/cholecystokinin family Tissue_fac PF01108.15 001361110.1_25023001_1 - 1.9e-12 46.8 0.0 3.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001361110.1_25023001_1 - 0.00032 20.8 0.0 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.19 001361110.1_25023001_1 - 0.0078 16.4 0.2 3.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Fibronectin type III domain Cys_knot PF00007.20 001309833.1_12822001_2 - 1.5e-35 121.5 10.9 2.1e-35 121.0 10.9 1.2 1 0 0 1 1 1 1 Cystine-knot domain IL15 PF02372.13 001303182.1_30822001_1 - 7.1e-53 178.1 4.3 9e-53 177.8 4.3 1.1 1 0 0 1 1 1 1 Interleukin 15 Trep_dent_lipo PF09710.8 001303182.1_30822001_1 - 0.004 16.0 2.7 0.005 15.7 2.7 1.1 1 0 0 1 1 1 1 Treponema clustered lipoprotein (Trep_dent_lipo) Ntox1 PF15500.4 001303182.1_30822001_1 - 0.069 13.4 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Tissue_fac PF01108.15 001361161.1_27729001_1 - 2.1e-06 27.4 0.2 5.7e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Tissue factor Tissue_fac PF01108.15 001360948.1_36825001_2 - 6.4e-09 35.5 0.1 1.3e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001361160.1_53626001_2 - 2.3e-05 24.0 0.0 5.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.15 001361162.1_25027001_3 - 1e-07 31.6 0.2 2.9e-07 30.1 0.2 1.8 1 1 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001361157.1_48323001_3 - 5.7e-07 29.7 4.8 6.4e-07 29.5 2.2 2.3 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001361157.1_48323001_3 - 5e-05 22.9 0.0 5e-05 22.9 0.0 3.1 5 0 0 5 5 5 1 Tissue factor Tissue_fac PF01108.15 001361163.1_25027001_2 - 0.036 13.7 0.3 0.036 13.7 0.3 2.4 2 1 0 2 2 2 0 Tissue factor CFEM PF05730.9 001361163.1_25027001_2 - 0.26 11.3 4.3 0.25 11.3 1.1 2.5 2 0 0 2 2 2 0 CFEM domain Tissue_fac PF01108.15 001361159.1_53629001_3 - 1.3e-05 24.8 0.0 8.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Tissue factor Tropomyosin PF00261.18 205446.1_23523001_3 - 5.4e-92 307.3 63.7 6.3e-92 307.1 63.7 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.5 205446.1_23523001_3 - 2.5e-24 85.9 60.4 2.9e-19 69.5 29.2 3.5 1 1 2 3 3 3 3 Tropomyosin like HrpB7 PF09486.8 205446.1_23523001_3 - 0.0013 19.0 43.5 0.002 18.4 18.3 3.2 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB7) YscO PF07321.10 205446.1_23523001_3 - 0.0092 15.8 2.4 0.0092 15.8 2.4 4.0 1 1 3 4 4 4 2 Type III secretion protein YscO Laminin_II PF06009.10 205446.1_23523001_3 - 0.0093 15.9 27.6 0.041 13.7 2.1 3.5 1 1 2 3 3 3 2 Laminin Domain II SlyX PF04102.10 205446.1_23523001_3 - 0.035 14.6 0.4 0.035 14.6 0.4 5.1 2 2 3 5 5 5 0 SlyX Reo_sigmaC PF04582.10 205446.1_23523001_3 - 0.074 12.3 4.0 0.27 10.4 0.9 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein HOOK PF05622.10 205446.1_23523001_3 - 0.097 10.7 42.2 0.12 10.3 42.2 1.1 1 0 0 1 1 1 0 HOOK protein Fib_alpha PF08702.8 205446.1_23523001_3 - 0.24 11.5 23.3 0.053 13.6 6.2 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.5 205446.1_23523001_3 - 0.36 10.2 40.8 0.15 11.4 31.3 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain IncA PF04156.12 205446.1_23523001_3 - 0.42 10.2 52.2 0.099 12.3 17.6 2.9 1 1 1 2 2 2 0 IncA protein TB PF00683.15 205446.1_23523001_3 - 0.46 10.1 4.3 0.2 11.2 0.5 2.3 2 0 0 2 2 2 0 TB domain DUF16 PF01519.14 205446.1_23523001_3 - 0.54 10.6 33.4 0.21 11.9 2.5 4.0 1 1 3 4 4 4 0 Protein of unknown function DUF16 CLZ PF16526.3 205446.1_23523001_3 - 0.58 10.4 37.2 0.31 11.3 4.7 4.4 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SNARE PF05739.17 205446.1_23523001_3 - 0.9 9.5 3.4 3 7.8 0.1 2.9 3 0 0 3 3 3 0 SNARE domain XhlA PF10779.7 205446.1_23523001_3 - 1.2 9.3 38.2 0.56 10.3 0.8 5.8 3 2 3 6 6 6 0 Haemolysin XhlA Golgin_A5 PF09787.7 205446.1_23523001_3 - 1.2 8.3 48.2 0.64 9.3 19.8 2.7 1 1 2 3 3 2 0 Golgin subfamily A member 5 EzrA PF06160.10 205446.1_23523001_3 - 1.8 6.5 44.4 0.54 8.3 8.1 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.7 205446.1_23523001_3 - 2.4 8.0 55.2 1.4 8.8 30.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.6 205446.1_23523001_3 - 3.3 7.6 50.7 0.027 14.3 12.6 5.0 2 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding BST2 PF16716.3 205446.1_23523001_3 - 5 7.6 33.8 0.17 12.3 6.6 3.6 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 ATG16 PF08614.9 205446.1_23523001_3 - 5.1 7.1 53.0 2.9 7.9 7.8 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HR1 PF02185.14 205446.1_23523001_3 - 6.7 6.8 37.8 0.46 10.5 12.7 4.6 2 1 1 4 4 4 0 Hr1 repeat Snapin_Pallidin PF14712.4 205446.1_23523001_3 - 8.9 6.7 26.0 4.5 7.7 0.0 4.8 2 1 3 5 5 5 0 Snapin/Pallidin DUF1664 PF07889.10 205446.1_23523001_3 - 9 6.2 25.1 2.9 7.8 2.8 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DNA_pol_E_B PF04042.14 001006493.1_23524001_2 - 6.1e-52 175.9 0.7 1.1e-51 175.1 0.7 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.6 001006493.1_23524001_2 - 1.5e-33 114.7 0.3 3.3e-33 113.7 0.3 1.6 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal DUF5100 PF17029.3 001006493.1_23524001_2 - 0.18 11.5 1.8 0.39 10.4 1.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5100) Ribosomal_S19 PF00203.19 001286309.1_53622001_3 - 5.6e-38 128.6 0.2 7.8e-38 128.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Prok_Ub PF14454.4 001286309.1_53622001_3 - 0.15 11.6 0.1 0.35 10.4 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin PDR_CDR PF06422.10 001146431.1_46923001_1 - 0.086 12.6 0.7 0.15 11.9 0.7 1.4 1 0 0 1 1 1 0 CDR ABC transporter VKOR PF07884.12 001146431.1_46923001_2 - 4.5e-08 33.2 0.3 4.5e-08 33.2 0.3 1.9 2 0 0 2 2 2 1 Vitamin K epoxide reductase family NADHdh_A3 PF14987.4 001245482.1_49921001_2 - 2.1e-32 111.2 0.1 2.1e-32 111.2 0.1 1.6 2 0 0 2 2 2 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 V-set PF07686.15 001137590.1_39123001_1 - 5.3e-24 84.3 1.6 1.4e-11 44.4 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.4 001137590.1_39123001_1 - 1.1e-16 61.0 0.8 1e-07 32.3 0.6 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001137590.1_39123001_1 - 9.8e-12 44.7 0.0 0.00015 21.6 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.4 001137590.1_39123001_1 - 2.7e-09 37.1 3.0 1.7e-05 24.9 0.4 3.2 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001137590.1_39123001_1 - 9.9e-07 28.7 7.0 0.0011 18.9 0.7 2.9 3 1 0 3 3 3 2 Immunoglobulin domain Syndecan PF01034.18 001137590.1_39123001_1 - 0.0059 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Syndecan domain Nucleoside_tran PF01733.16 001137590.1_39123001_1 - 0.048 12.9 0.6 0.1 11.9 0.1 1.7 2 0 0 2 2 2 0 Nucleoside transporter RSN1_TM PF13967.4 001137590.1_39123001_1 - 0.082 12.5 1.0 1.7 8.3 0.0 2.6 3 0 0 3 3 3 0 Late exocytosis, associated with Golgi transport APG5 PF04106.10 001267627.1_23623001_2 - 4.5e-59 199.4 0.0 6.1e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 Peptidase_M99 PF17033.3 001267627.1_23623001_2 - 0.13 11.5 0.0 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 Carboxypeptidase controlling helical cell shape catalytic VWD PF00094.23 001267629.1_23627001_2 - 2.1e-34 119.0 9.8 2.1e-14 54.0 0.0 3.5 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.9 001267629.1_23627001_2 - 7.4e-19 67.8 11.9 4e-16 59.1 0.4 5.0 6 0 0 6 6 6 2 C8 domain TIL PF01826.15 001267629.1_23627001_2 - 4.3e-08 33.1 42.1 3.8e-05 23.7 12.7 8.5 7 2 1 8 8 8 3 Trypsin Inhibitor like cysteine rich domain VWC PF00093.16 001267629.1_23627001_2 - 0.00024 21.2 8.4 0.00024 21.2 8.4 7.8 4 3 3 7 7 7 2 von Willebrand factor type C domain APG6 PF04111.10 001267632.1_23624001_1 - 2.5e-126 421.2 7.6 3.4e-126 420.7 7.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 BH3 PF15285.4 001267632.1_23624001_1 - 7.8e-17 60.5 0.2 1.6e-16 59.5 0.2 1.5 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting Exonuc_VII_L PF02601.13 001267632.1_23624001_1 - 0.0012 18.3 2.6 0.0024 17.4 2.6 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit SPAM PF02090.13 001267632.1_23624001_1 - 0.013 15.2 10.1 0.022 14.4 10.1 1.4 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF342 PF03961.11 001267632.1_23624001_1 - 0.13 10.7 11.5 0.23 9.9 10.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Suppressor_APC PF11414.6 001267632.1_23624001_1 - 0.35 10.8 10.0 0.96 9.4 10.0 1.8 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Seryl_tRNA_N PF02403.20 001267632.1_23624001_1 - 0.57 10.3 9.0 1.2 9.3 9.0 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2968 PF11180.6 001267632.1_23624001_1 - 1 8.9 15.9 0.76 9.3 14.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) FlgN PF05130.10 001267632.1_23624001_1 - 3.5 8.0 17.1 7.4 6.9 17.1 1.5 1 1 0 1 1 1 0 FlgN protein Glyco_transf_29 PF00777.16 001267634.1_23623001_1 - 6.7e-75 251.8 0.1 9.3e-75 251.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) MMADHC PF10229.7 001267634.1_23623001_1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein MOZART2 PF12926.5 001245512.1_49922001_1 - 1.6e-31 107.6 0.0 2.7e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Globin PF00042.20 001267638.1_23622001_2 - 1.6e-26 92.9 0.0 3.1e-26 92.0 0.0 1.5 2 0 0 2 2 2 1 Globin COX16 PF14138.4 001165169.1_36922001_2 - 6.8e-07 29.6 2.8 2.5e-06 27.8 2.8 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 S_100 PF01023.17 001165171.1_36922001_1 - 2.9e-16 58.7 0.1 4.9e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.4 001165171.1_36922001_1 - 3e-07 30.7 0.2 5.2e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.30 001165171.1_36922001_1 - 2e-06 26.8 0.2 9.7e-06 24.7 0.1 2.2 2 1 0 2 2 2 1 EF hand EF-hand_6 PF13405.4 001165171.1_36922001_1 - 7.9e-05 22.2 0.2 0.071 13.0 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.4 001165171.1_36922001_1 - 0.00011 21.4 0.5 0.0003 20.0 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.4 001165171.1_36922001_1 - 0.00097 18.7 0.4 0.0017 17.9 0.4 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.5 001165171.1_36922001_1 - 0.082 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DM PF00751.16 001267642.1_23622001_1 - 1.5e-22 79.1 10.5 1.5e-22 79.1 10.5 1.9 2 0 0 2 2 2 1 DM DNA binding domain Dmrt1 PF12374.6 001267642.1_23622001_1 - 6.2e-21 74.5 3.8 6.2e-21 74.5 3.8 2.3 2 0 0 2 2 2 1 Double-sex mab3 related transcription factor 1 GCFC PF07842.10 001267643.1_23626001_2 - 3.2e-98 328.6 19.3 4.6e-98 328.1 16.6 2.2 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.6 001267643.1_23626001_2 - 1.6e-26 92.6 9.7 1.6e-26 92.6 9.7 1.9 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.21 001267643.1_23626001_2 - 2.3e-16 59.3 5.0 4.7e-16 58.3 5.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.5 001267643.1_23626001_2 - 0.00014 21.7 1.6 0.00038 20.4 1.6 1.7 1 0 0 1 1 1 1 G-patch domain Rab5-bind PF09311.9 001267643.1_23626001_2 - 0.1 11.9 1.5 0.17 11.1 1.5 1.3 1 0 0 1 1 1 0 Rabaptin-like protein VCBS PF13517.4 001267644.1_23624001_2 - 5.5e-32 110.0 28.5 2.2e-11 44.1 0.7 5.5 4 2 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.21 001267644.1_23624001_2 - 3.4e-14 52.5 22.3 1.6e-05 24.8 0.1 5.9 6 0 0 6 6 6 4 FG-GAP repeat UnbV_ASPIC PF07593.10 001267644.1_23624001_2 - 8.2e-13 48.0 0.1 1.9e-12 46.8 0.1 1.7 1 0 0 1 1 1 1 ASPIC and UnbV TcdB_toxin_midN PF12256.6 001267644.1_23624001_2 - 0.0012 18.1 1.5 6 6.1 0.0 4.0 4 0 0 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region BBS1 PF14779.4 001267644.1_23624001_2 - 0.098 11.9 0.0 11 5.3 0.0 2.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 1 DUF737 PF05300.9 001141562.1_46923001_3 - 1.6e-48 165.6 15.4 2.1e-48 165.2 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF737) CHCH PF06747.11 001141562.1_46923001_3 - 0.00086 19.2 3.6 0.00086 19.2 3.6 1.8 2 0 0 2 2 2 1 CHCH domain GrpE PF01025.17 001141562.1_46923001_3 - 0.048 13.2 5.9 0.079 12.5 5.9 1.4 1 0 0 1 1 1 0 GrpE GMC_oxred_C PF05199.11 001141562.1_46923001_3 - 0.12 12.7 0.0 0.85 10.0 0.0 2.1 1 1 0 2 2 2 0 GMC oxidoreductase PAS_3 PF08447.10 001267649.1_23625001_1 - 6.7e-27 93.5 0.0 1.5e-20 73.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001267649.1_23625001_1 - 2.6e-22 78.9 0.6 8.5e-19 67.6 0.1 2.6 2 0 0 2 2 2 2 PAS domain HIF-1a_CTAD PF08778.8 001267649.1_23625001_1 - 5.7e-20 70.5 2.2 1.5e-19 69.1 2.2 1.8 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.6 001267649.1_23625001_1 - 1.6e-17 62.5 6.4 1.6e-17 62.5 6.4 2.4 2 0 0 2 2 2 1 Hypoxia-inducible factor-1 PAS PF00989.23 001267649.1_23625001_1 - 3.5e-16 59.1 0.0 9.5e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.5 001267649.1_23625001_1 - 6.4e-10 39.1 0.0 0.0011 19.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001267649.1_23625001_1 - 1.8e-07 31.2 0.0 0.0034 17.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.9 001267649.1_23625001_1 - 0.11 13.0 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 PAS fold HLH PF00010.24 001267649.1_23625001_1 - 0.13 12.2 0.3 0.69 9.8 0.0 2.3 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Glyco_transf_29 PF00777.16 001267651.1_23623001_1 - 3.5e-76 256.0 0.0 4.3e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Guanylate_kin PF00625.19 001267653.1_23624001_1 - 3.1e-47 160.5 0.1 5.7e-47 159.6 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.6 001267653.1_23624001_1 - 2.2e-14 53.1 12.8 3.4e-09 36.5 1.4 2.8 2 0 0 2 2 2 2 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.26 001267653.1_23624001_1 - 0.0035 16.8 0.1 0.013 14.9 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.4 001267653.1_23624001_1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.15 001267653.1_23624001_1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain p450 PF00067.20 001267655.1_23624001_1 - 3.6e-116 388.5 0.0 4.3e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_29 PF00777.16 001267660.1_23624001_1 - 2.3e-36 125.4 0.0 3.8e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Gal-bind_lectin PF00337.20 001200929.1_26622001_3 - 7e-25 87.0 0.1 1.3e-24 86.1 0.1 1.5 1 1 1 2 2 2 1 Galactoside-binding lectin DED PF01335.19 001267666.1_23626001_2 - 7.5e-25 86.9 1.7 9.4e-22 77.0 0.4 2.5 2 0 0 2 2 2 2 Death effector domain Peptidase_C14 PF00656.20 001267666.1_23626001_2 - 2.5e-13 50.4 0.0 4.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain COesterase PF00135.26 001267670.1_23626001_1 - 1.9e-194 647.2 0.0 2.4e-194 646.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001267670.1_23626001_1 - 2.1e-07 30.9 0.1 1.2e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sarcoglycan_2 PF05510.11 001267670.1_23626001_1 - 0.13 10.9 0.2 0.22 10.1 0.2 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon I-set PF07679.14 001267671.1_23625001_1 - 6.1e-17 61.3 0.0 1.9e-16 59.7 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 001267671.1_23625001_1 - 1.2e-08 35.3 0.0 3.6e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001267671.1_23625001_1 - 3.9e-05 23.6 0.1 0.00027 20.9 0.1 2.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001267671.1_23625001_1 - 0.055 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Pkinase PF00069.23 001267675.1_23626001_3 - 1.2e-41 142.7 0.0 2e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001267675.1_23626001_3 - 5e-28 98.0 0.0 1.1e-22 80.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase dsrm PF00035.24 001267675.1_23626001_3 - 1.8e-21 76.4 0.2 1.2e-11 44.9 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif Kinase-like PF14531.4 001267675.1_23626001_3 - 0.077 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SOCS_box PF07525.14 001267678.1_23622001_1 - 3.8e-13 49.4 1.0 6.4e-13 48.7 1.0 1.4 1 0 0 1 1 1 1 SOCS box SH2 PF00017.22 001267678.1_23622001_1 - 1.7e-11 43.9 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH2 PF00017.22 001267679.1_23624001_1 - 2.2e-12 46.7 0.2 6e-12 45.3 0.1 1.9 2 0 0 2 2 2 1 SH2 domain SOCS_box PF07525.14 001267679.1_23624001_1 - 9.9e-12 44.9 1.7 5.6e-11 42.5 1.5 2.2 2 0 0 2 2 2 1 SOCS box SOCS PF12610.6 001267680.1_23624001_1 - 1.2e-14 54.3 0.1 4.1e-14 52.6 0.1 2.0 1 0 0 1 1 1 1 Suppressor of cytokine signalling SH2 PF00017.22 001267680.1_23624001_1 - 5.4e-09 35.9 0.0 9.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.14 001267680.1_23624001_1 - 1.2e-07 31.8 0.0 2.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 SOCS box IL15 PF02372.13 001267682.1_23621001_1 - 2.7e-09 37.0 0.3 3.1e-09 36.8 0.3 1.0 1 0 0 1 1 1 1 Interleukin 15 IL15 PF02372.13 001267684.1_23622001_1 - 2.4e-11 43.7 0.2 3.1e-11 43.3 0.2 1.2 1 0 0 1 1 1 1 Interleukin 15 IL15 PF02372.13 001267687.1_23621001_1 - 5.1e-15 55.5 0.3 6.4e-15 55.2 0.3 1.1 1 0 0 1 1 1 1 Interleukin 15 SOCS PF12610.6 001267689.1_23624001_1 - 9.6e-19 67.4 3.8 9.6e-19 67.4 3.8 3.2 3 0 0 3 3 3 1 Suppressor of cytokine signalling SOCS_box PF07525.14 001267689.1_23624001_1 - 2.2e-09 37.3 0.1 1.4e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 SOCS box SH2 PF00017.22 001267689.1_23624001_1 - 2.4e-08 33.8 0.0 4.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 SH2 domain MSSP PF03940.11 001267689.1_23624001_1 - 0.19 11.2 1.6 0.41 10.1 1.6 1.5 1 0 0 1 1 1 0 Male specific sperm protein Filament PF00038.19 001100432.1_12425001_2 - 3.4e-54 184.4 52.5 5.9e-54 183.6 52.5 1.4 1 0 0 1 1 1 1 Intermediate filament protein Snapin_Pallidin PF14712.4 001100432.1_12425001_2 - 0.0023 18.2 4.2 0.0023 18.2 4.2 5.2 3 1 4 7 7 7 1 Snapin/Pallidin TetR_C_4 PF08359.9 001100432.1_12425001_2 - 0.56 10.2 7.7 0.52 10.3 5.3 2.2 2 0 0 2 2 2 0 YsiA-like protein, C-terminal region CP12 PF02672.13 001100432.1_12425001_2 - 0.9 10.2 7.5 0.48 11.1 0.1 3.3 3 1 1 4 4 4 0 CP12 domain TraF_2 PF13729.4 001100432.1_12425001_2 - 1.2 8.3 4.7 0.66 9.2 0.5 2.2 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein DUF1515 PF07439.9 001100432.1_12425001_2 - 8.1 6.4 7.9 7 6.6 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Ribosomal_L35Ae PF01247.16 001245613.1_49921001_1 - 7.9e-47 157.3 0.3 9.9e-47 157.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae DUF2080 PF09853.7 001245613.1_49921001_1 - 0.1 12.2 0.3 0.35 10.5 0.0 2.0 3 0 0 3 3 3 0 Putative transposon-encoded protein (DUF2080) Cys_Met_Meta_PP PF01053.18 001124685.1_36923001_1 - 4.8e-154 512.4 0.0 5.4e-154 512.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.19 001124685.1_36923001_1 - 4.4e-06 26.0 0.1 6.3e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.9 001124685.1_36923001_1 - 0.00018 20.0 0.0 0.00024 19.6 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.17 001124685.1_36923001_1 - 0.00037 19.4 0.4 0.00058 18.8 0.4 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.15 001124685.1_36923001_1 - 0.00045 19.5 0.5 0.00076 18.7 0.5 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family P-mevalo_kinase PF04275.12 001245642.1_49922001_3 - 4.1e-46 155.5 0.0 5.8e-46 155.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomevalonate kinase CPT_N PF16484.3 001245642.1_49922001_3 - 0.048 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus 7tm_1 PF00001.19 001033824.1_12423001_1 - 5.2e-33 114.3 12.8 8e-33 113.7 12.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ERM PF00769.17 001032427.1_12426001_2 - 1.4e-49 169.0 64.1 1.4e-49 169.0 64.1 2.3 2 0 0 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.8 001032427.1_12426001_2 - 1e-26 93.0 0.1 3.6e-26 91.2 0.0 2.0 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.16 001032427.1_12426001_2 - 5.8e-26 91.1 0.6 5.8e-26 91.1 0.6 3.5 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.8 001032427.1_12426001_2 - 2.4e-13 49.7 0.1 8.5e-13 47.9 0.1 2.0 2 0 0 2 2 2 1 FERM N-terminal domain zf-C2H2 PF00096.24 001078560.1_12423001_3 - 0.0059 16.9 0.7 0.014 15.7 0.7 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001078573.1_12426001_3 - 1.6e-42 141.9 59.0 1.1e-08 35.0 0.5 9.2 10 0 0 10 10 8 8 Zinc-finger double domain zf-C2H2 PF00096.24 001078573.1_12426001_3 - 1.2e-32 110.3 66.1 8.7e-05 22.6 0.3 9.8 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001078573.1_12426001_3 - 2.3e-29 99.4 63.3 0.00064 20.2 0.8 9.8 9 0 0 9 9 9 9 C2H2-type zinc finger CUT PF02376.13 001078573.1_12426001_3 - 6e-22 77.5 0.0 2.4e-21 75.6 0.0 2.0 2 0 0 2 2 2 1 CUT domain zf-met PF12874.5 001078573.1_12426001_3 - 1.4e-10 41.0 46.0 0.012 15.8 0.2 9.2 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001078573.1_12426001_3 - 2e-06 27.4 53.4 0.086 12.7 0.3 9.3 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001078573.1_12426001_3 - 5.3e-05 23.3 31.8 0.7 10.2 0.0 8.5 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.12 001078573.1_12426001_3 - 0.0088 15.7 3.6 0.063 13.0 1.3 3.2 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Di19 PF05605.10 001078573.1_12426001_3 - 0.018 15.2 4.4 0.018 15.2 4.4 6.9 2 2 5 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.4 001078573.1_12426001_3 - 0.043 13.5 0.2 0.043 13.5 0.2 7.9 8 0 0 8 8 8 0 C2H2-type zinc-finger domain DUF2197 PF09963.7 001078573.1_12426001_3 - 0.15 12.2 7.8 0.34 11.1 0.5 3.7 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2197) BolA PF01722.16 001078573.1_12426001_3 - 4 7.6 13.0 2.2 8.5 1.0 5.1 3 1 1 4 4 4 0 BolA-like protein Zn-ribbon_8 PF09723.8 001078573.1_12426001_3 - 5.4 7.1 31.8 2.7 8.1 1.5 6.7 6 1 1 7 7 7 0 Zinc ribbon domain Noggin PF05806.10 001078600.1_50022001_1 - 1.6e-36 126.1 1.4 2e-36 125.8 1.4 1.1 1 0 0 1 1 1 1 Noggin TGF_beta PF00019.18 001032671.1_50023001_1 - 1.9e-27 96.0 2.1 2.7e-27 95.5 0.7 2.0 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 001032671.1_50023001_1 - 1e-22 81.0 0.2 1.2e-21 77.5 0.2 2.0 1 1 0 1 1 1 1 TGF-beta propeptide Glyco_transf_10 PF00852.17 001032697.1_50022001_1 - 2.2e-56 190.3 0.4 3e-56 189.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.3 001032697.1_50022001_1 - 1.4e-35 122.0 0.0 5.5e-35 120.0 0.0 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Exostosin PF03016.13 001032697.1_50022001_1 - 0.027 13.6 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Exostosin family Med7 PF05983.9 001032697.1_50022001_1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 MED7 protein p450 PF00067.20 001105236.1_50024001_1 - 1.9e-134 448.8 0.0 2.3e-134 448.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ectatomin PF06457.9 001105236.1_50024001_2 - 0.002 17.9 0.5 0.011 15.5 0.5 2.4 1 0 0 1 1 1 1 Ectatomin DUF3254 PF11630.6 001105236.1_50024001_3 - 0.089 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) Ald_Xan_dh_C2 PF02738.16 001281542.1_30929001_1 - 5e-179 596.1 0.0 7e-179 595.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001281542.1_30929001_1 - 1.1e-34 119.5 0.0 2.1e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.15 001281542.1_30929001_1 - 1.9e-29 101.7 0.0 3.6e-27 94.4 0.0 2.9 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.18 001281542.1_30929001_1 - 3.7e-29 100.4 0.5 1e-28 99.0 0.5 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.20 001281542.1_30929001_1 - 5.4e-26 91.0 2.0 1.1e-25 90.0 2.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.25 001281542.1_30929001_1 - 0.00011 21.9 5.2 0.00056 19.7 0.7 3.5 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Methyltransf_3 PF01596.15 001282103.1_22322001_1 - 2.6e-16 59.3 0.0 3.5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001282103.1_22322001_1 - 2.5e-12 47.6 0.0 4.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001282103.1_22322001_1 - 0.043 13.5 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.17 001282103.1_22322001_1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NAD_binding_4 PF07993.10 001302697.1_52324001_1 - 1e-78 264.0 0.0 1.4e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.17 001302697.1_52324001_1 - 4.2e-32 110.1 2.2 1.1e-31 108.7 2.2 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.19 001302697.1_52324001_1 - 6.5e-10 38.7 0.3 1e-08 34.8 0.1 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001302697.1_52324001_1 - 1.1e-08 34.7 0.1 3.8e-08 32.9 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.17 001302697.1_52324001_1 - 1.3e-08 34.0 0.0 1.5e-05 24.0 0.0 3.1 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.13 001302697.1_52324001_1 - 1.1e-06 27.9 0.1 3.6e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.22 001302697.1_52324001_1 - 4.8e-05 23.7 0.0 0.00021 21.6 0.0 2.0 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.15 001302697.1_52324001_1 - 0.001 18.1 0.1 0.061 12.3 0.1 2.9 2 1 0 2 2 2 1 RmlD substrate binding domain KR PF08659.8 001302697.1_52324001_1 - 0.027 14.2 0.0 0.059 13.1 0.0 1.6 1 1 0 1 1 1 0 KR domain DapB_N PF01113.18 001302697.1_52324001_1 - 0.079 13.0 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Troponin PF00992.18 001303224.1_30822001_1 - 3.5e-37 127.6 0.6 6.9e-37 126.6 0.6 1.5 1 0 0 1 1 1 1 Troponin Troponin-I_N PF11636.6 001303224.1_30822001_1 - 5.4e-08 32.5 0.7 1.5e-07 31.1 0.7 1.7 1 0 0 1 1 1 1 Troponin I residues 1-32 DUF3418 PF11898.6 001303224.1_30822001_1 - 0.02 13.4 0.9 0.025 13.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) CENP-H PF05837.10 001303224.1_30822001_1 - 1.8 8.9 5.9 1.1 9.6 0.1 2.5 2 1 1 3 3 3 0 Centromere protein H (CENP-H) PAX PF00292.16 001303185.1_30824001_1 - 6.1e-74 245.8 0.8 9.2e-74 245.2 0.8 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.27 001303185.1_30824001_1 - 5.8e-26 89.9 9.6 2.5e-17 62.3 3.5 2.7 1 1 1 2 2 2 2 Homeobox domain Pax7 PF12360.6 001303185.1_30824001_1 - 1.1e-19 70.1 8.6 2.6e-19 69.0 8.6 1.6 1 0 0 1 1 1 1 Paired box protein 7 Homeobox_KN PF05920.9 001303185.1_30824001_1 - 3e-05 23.7 0.8 9.7e-05 22.1 0.8 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_32 PF13565.4 001303185.1_30824001_1 - 7.1e-05 23.2 5.6 0.0028 18.1 0.0 3.5 2 2 1 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.4 001303185.1_30824001_1 - 7.5e-05 22.3 2.2 0.0026 17.4 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.5 001303185.1_30824001_1 - 0.15 11.5 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain Death PF00531.20 001303200.1_30825001_3 - 8.9e-18 64.1 1.0 2.5e-17 62.7 0.0 2.1 3 0 0 3 3 3 1 Death domain TNFR_c6 PF00020.16 001303200.1_30825001_3 - 3.2e-16 59.3 34.4 5.6e-08 32.9 11.9 3.8 2 1 1 3 3 3 3 TNFR/NGFR cysteine-rich region Myosin_head PF00063.19 001303284.1_36029001_3 - 2.5e-277 921.5 8.1 2.5e-277 921.5 8.1 3.3 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.17 001303284.1_36029001_3 - 1.4e-154 516.4 252.5 1.7e-154 516.1 252.5 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.17 001303284.1_36029001_3 - 2.5e-09 36.6 0.7 8.9e-09 34.9 0.7 2.1 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain HALZ PF02183.16 001303284.1_36029001_3 - 0.0028 17.7 1.7 0.0028 17.7 1.7 11.9 15 1 1 16 16 16 2 Homeobox associated leucine zipper AAA_22 PF13401.4 001303284.1_36029001_3 - 0.097 12.8 0.0 0.097 12.8 0.0 5.8 3 2 3 6 6 6 0 AAA domain Reo_sigmaC PF04582.10 001303284.1_36029001_3 - 0.4 9.9 68.8 0.037 13.3 2.4 9.1 1 1 10 11 11 11 0 Reovirus sigma C capsid protein AAA_16 PF13191.4 001303284.1_36029001_3 - 0.45 10.7 0.0 0.45 10.7 0.0 5.2 4 1 1 5 5 5 0 AAA ATPase domain Sigma54_AID PF00309.18 001303284.1_36029001_3 - 3.6 7.4 10.6 0.18 11.5 2.4 3.3 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) Apolipoprotein PF01442.16 001303288.1_36022001_2 - 9.9e-06 25.5 5.5 2.7e-05 24.0 5.6 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain AAA_13 PF13166.4 001303288.1_36022001_2 - 0.0011 17.6 2.4 0.0014 17.3 2.4 1.0 1 0 0 1 1 1 1 AAA domain DHC_N1 PF08385.10 001303288.1_36022001_2 - 0.0089 14.6 0.5 0.011 14.3 0.5 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Mod_r PF07200.11 001303288.1_36022001_2 - 0.0095 15.9 2.3 0.014 15.4 2.3 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TrbC PF04956.11 001303288.1_36022001_2 - 0.013 15.6 2.3 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family ApoA-II PF04711.11 001303288.1_36022001_2 - 0.037 14.1 2.7 0.069 13.2 0.7 2.1 1 1 1 2 2 2 0 Apolipoprotein A-II (ApoA-II) Baculo_PEP_C PF04513.10 001303288.1_36022001_2 - 0.044 13.7 6.4 0.41 10.6 6.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSCB_C PF07743.11 001303288.1_36022001_2 - 0.054 13.9 4.5 1.7 9.1 0.8 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF2497 PF10691.7 001303288.1_36022001_2 - 0.097 13.0 0.8 2.6 8.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Phage_Mu_Gam PF07352.10 001303288.1_36022001_2 - 0.18 11.6 3.4 0.46 10.2 3.4 1.7 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein YlqD PF11068.6 001303288.1_36022001_2 - 0.25 11.6 8.8 0.33 11.2 8.3 1.4 1 1 0 1 1 1 0 YlqD protein DUF948 PF06103.9 001303288.1_36022001_2 - 0.25 11.5 4.6 6.3 7.0 4.6 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.14 001303288.1_36022001_2 - 0.43 10.7 9.5 0.27 11.3 1.5 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein BLOC1_2 PF10046.7 001303288.1_36022001_2 - 1.5 9.1 5.9 9.9 6.4 1.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.4 001303288.1_36022001_2 - 1.8 8.5 13.4 3 7.7 13.2 1.5 1 1 0 1 1 1 0 FlxA-like protein DUF3373 PF11853.6 001303288.1_36022001_2 - 3.3 6.2 5.4 57 2.1 5.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Transferrin PF00405.15 001303296.1_36025001_3 - 5.5e-192 637.0 10.3 9.2e-104 347.0 1.0 2.1 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.5 001303296.1_36025001_3 - 1.5e-09 37.7 0.0 0.00018 21.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter, phosphonate, periplasmic substrate-binding protein Lipocalin PF00061.21 001303291.1_36022001_1 - 6.1e-23 81.5 1.9 7.4e-23 81.2 1.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001303291.1_36022001_1 - 1.2e-06 28.3 1.0 1.8e-06 27.8 1.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family EF-hand_1 PF00036.30 001303295.1_36021001_1 - 1.7e-11 42.7 5.4 6.6e-06 25.2 0.9 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 001303295.1_36021001_1 - 1.8e-11 44.2 0.3 2.8e-11 43.6 0.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.4 001303295.1_36021001_1 - 1.2e-09 37.2 4.0 0.00014 21.1 0.5 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.4 001303295.1_36021001_1 - 2.8e-09 36.0 1.3 2.8e-05 23.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.4 001303295.1_36021001_1 - 1e-06 28.3 2.2 1.8e-06 27.5 0.5 2.1 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001303295.1_36021001_1 - 0.028 14.6 0.0 0.042 14.0 0.0 1.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PTR2 PF00854.19 001303366.1_27626001_2 - 5.7e-131 436.9 12.2 2.5e-120 401.8 8.7 2.2 2 0 0 2 2 2 2 POT family DUF4397 PF14344.4 001303366.1_27626001_2 - 0.0097 16.6 0.1 0.029 15.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4397) DUF2681 PF10883.6 001303366.1_27626001_2 - 1.2 9.4 0.0 1.2 9.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) zf-DHHC PF01529.18 001078596.1_50027001_1 - 7e-35 119.9 11.9 7e-35 119.9 11.9 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ig_3 PF13927.4 001098658.1_50024001_1 - 1.5e-30 105.4 9.8 9.3e-08 32.5 0.0 5.8 5 1 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.4 001098658.1_50024001_1 - 9.5e-28 96.2 3.1 6e-07 29.6 0.4 5.3 5 1 0 5 5 5 4 Immunoglobulin domain C2-set_2 PF08205.10 001098658.1_50024001_1 - 7.2e-20 70.7 1.6 4.9e-13 48.8 0.0 4.9 5 1 0 5 5 5 2 CD80-like C2-set immunoglobulin domain ig PF00047.23 001098658.1_50024001_1 - 1.1e-18 67.0 3.6 0.0097 15.9 0.0 6.1 5 1 0 5 5 5 4 Immunoglobulin domain I-set PF07679.14 001098658.1_50024001_1 - 1.2e-13 50.8 16.1 0.0041 17.0 0.1 7.8 6 3 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.15 001098658.1_50024001_1 - 4.7e-09 36.3 0.2 0.00026 21.0 0.0 4.4 4 1 1 5 5 5 2 Immunoglobulin V-set domain C1-set PF07654.13 001098658.1_50024001_1 - 1.8e-08 34.6 0.8 0.0077 16.6 0.0 5.3 5 1 0 5 5 5 1 Immunoglobulin C1-set domain Herpes_gE PF02480.14 001098658.1_50024001_1 - 0.00014 20.6 0.1 2.8 6.5 0.0 3.1 3 0 0 3 3 3 3 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.10 001098658.1_50024001_1 - 0.0033 16.9 0.1 0.0058 16.1 0.1 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family C2-set PF05790.13 001098658.1_50024001_1 - 0.008 16.2 2.2 1.9 8.6 0.0 4.7 4 1 2 6 6 6 1 Immunoglobulin C2-set domain DUF1191 PF06697.10 001098658.1_50024001_1 - 0.0092 15.1 0.2 0.083 12.0 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1191) DUF4366 PF14283.4 001098658.1_50024001_1 - 0.0095 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) SKG6 PF08693.8 001098658.1_50024001_1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.18 001098658.1_50024001_1 - 0.04 13.7 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain DUF2650 PF10853.6 001098658.1_50024001_3 - 2.8 7.6 7.5 0.93 9.2 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Filament PF00038.19 001097807.1_53423001_1 - 1.1e-104 350.3 31.1 1.3e-104 350.1 31.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.10 001097807.1_53423001_1 - 0.0014 18.6 1.0 0.0014 18.6 1.0 4.1 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein IncA PF04156.12 001097807.1_53423001_1 - 0.0016 18.1 22.3 0.13 11.9 15.1 3.3 2 1 1 3 3 3 1 IncA protein Spc7 PF08317.9 001097807.1_53423001_1 - 0.006 15.4 33.0 0.059 12.1 12.5 3.2 1 1 2 3 3 3 3 Spc7 kinetochore protein DUF4407 PF14362.4 001097807.1_53423001_1 - 0.0066 15.7 18.1 1.1 8.4 16.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) GDH_N PF12466.6 001097807.1_53423001_1 - 0.11 12.6 0.1 0.41 10.8 0.1 2.1 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Laminin_II PF06009.10 001097807.1_53423001_1 - 0.33 10.8 19.3 0.071 13.0 4.8 3.6 2 1 1 3 3 3 0 Laminin Domain II UPF0184 PF03670.11 001097807.1_53423001_1 - 0.66 10.3 4.5 1.6 9.0 0.0 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) CENP-F_leu_zip PF10473.7 001097807.1_53423001_1 - 1.9 8.3 35.9 0.2 11.6 9.7 4.8 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.10 001097807.1_53423001_1 - 2.2 7.5 11.0 4.3 6.5 0.7 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Jnk-SapK_ap_N PF09744.7 001097807.1_53423001_1 - 2.2 8.3 29.1 4.6 7.3 6.9 3.5 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.7 001097807.1_53423001_1 - 2.8 8.2 17.1 3.1 8.1 0.1 4.1 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lectin_N PF03954.12 001097807.1_53423001_1 - 3.6 7.2 12.4 3.8 7.1 3.9 3.3 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain SlyX PF04102.10 001097807.1_53423001_1 - 5.3 7.6 26.0 0.64 10.6 0.4 5.3 3 1 2 5 5 5 0 SlyX ProSAAS PF07259.10 033288.1_53421120_2 - 0.0075 16.1 0.1 0.0086 15.9 0.1 1.1 1 0 0 1 1 1 1 ProSAAS precursor p450 PF00067.20 001302367.1_41625001_3 - 3.7e-133 444.5 0.3 4.4e-133 444.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001302360.1_41624001_2 - 6.2e-148 493.2 0.0 7.4e-148 493.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001302366.1_41626001_3 - 8.5e-139 463.1 0.0 9.9e-139 462.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 4F5 PF04419.12 001245395.1_49921001_1 - 3.4e-11 43.7 10.7 3.4e-11 43.7 10.7 2.6 3 0 0 3 3 3 1 4F5 protein family TFIIS_C PF01096.16 001245455.1_49922001_3 - 4.2e-20 71.2 6.8 4.2e-20 71.2 6.8 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.6 001245455.1_49922001_3 - 0.042 13.4 0.3 0.087 12.4 0.3 1.5 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain PAS_3 PF08447.10 001302362.1_41629001_1 - 8.9e-18 64.2 0.1 4.8e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001302362.1_41629001_1 - 4.8e-13 49.1 0.0 3.8e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 001302362.1_41629001_1 - 2.3e-09 37.1 0.0 7.9e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 PAS fold HLH PF00010.24 001302362.1_41629001_1 - 3.5e-05 23.5 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.8 001302362.1_41629001_1 - 0.0038 17.3 0.0 0.0096 16.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.5 001302362.1_41629001_1 - 0.01 16.0 0.0 0.048 13.8 0.0 2.0 2 0 0 2 2 2 0 PAS domain PAS_3 PF08447.10 001302361.1_41626001_1 - 6.6e-19 67.9 0.1 1.5e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001302361.1_41626001_1 - 1.5e-14 54.0 1.0 6.7e-11 42.2 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS PF00989.23 001302361.1_41626001_1 - 4.9e-13 48.9 2.2 1.3e-11 44.4 0.0 3.1 3 0 0 3 3 3 1 PAS fold HLH PF00010.24 001302361.1_41626001_1 - 2e-05 24.4 0.1 4.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.8 001302361.1_41626001_1 - 0.0029 17.7 1.6 0.081 13.0 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.5 001302361.1_41626001_1 - 0.01 15.9 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 0 PAS domain Actin PF00022.17 001309832.1_12823001_1 - 3.3e-148 493.5 0.0 9.6e-148 492.0 0.0 1.6 1 1 0 1 1 1 1 Actin Troponin PF00992.18 001309830.1_12822001_2 - 6.4e-38 129.9 4.6 8.6e-38 129.5 4.6 1.2 1 0 0 1 1 1 1 Troponin Frigida PF07899.9 001309830.1_12822001_2 - 0.41 9.8 6.9 0.042 13.0 1.1 2.1 2 1 0 2 2 2 0 Frigida-like protein Actin PF00022.17 001309834.1_12824001_2 - 1.7e-149 497.7 0.0 4.9e-149 496.2 0.0 1.6 1 1 0 1 1 1 1 Actin Fer4_7 PF12838.5 001303760.1_21523001_1 - 0.021 15.3 0.3 0.27 11.7 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.5 001303760.1_21523001_1 - 0.14 12.6 8.1 0.25 11.8 2.7 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Synuclein PF01387.15 001303760.1_21523001_3 - 3.8e-44 150.0 17.2 6e-44 149.3 17.2 1.3 1 0 0 1 1 1 1 Synuclein P5CR_dimer PF14748.4 001303760.1_21523001_3 - 0.061 13.4 5.6 0.085 13.0 4.4 1.8 1 1 1 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation 7tm_1 PF00001.19 001310825.1_02123001_2 - 1.3e-30 106.4 8.6 3.3e-30 105.1 8.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001310825.1_02123001_2 - 0.00019 20.8 0.3 0.00024 20.4 0.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.7 001310825.1_02123001_2 - 0.0039 16.5 0.3 0.0056 16.0 0.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001310825.1_02123001_2 - 0.055 12.6 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Leptin PF02024.13 001311191.1_24822001_1 - 2.7e-25 88.7 0.0 3.4e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Leptin p450 PF00067.20 001279576.1_37525001_1 - 9.9e-102 340.9 0.0 1.1e-101 340.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Leptin PF02024.13 001301050.1_37521001_1 - 9.1e-06 25.4 0.0 1.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Leptin Insulin PF00049.16 001279636.1_37524001_2 - 0.00043 21.1 3.7 0.25 12.2 1.3 2.6 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family Pkinase_Tyr PF07714.15 001309405.1_37525001_2 - 3.1e-94 315.0 0.0 4e-94 314.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001309405.1_37525001_2 - 4.5e-48 163.8 0.0 6.5e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.22 001309405.1_37525001_2 - 5.3e-25 87.2 0.1 1.1e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.26 001309405.1_37525001_2 - 7.7e-16 57.3 0.1 1.7e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001309405.1_37525001_2 - 1.1e-09 37.7 0.0 2.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 001309405.1_37525001_2 - 2.1e-09 37.0 0.1 4.1e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kdo PF06293.12 001309405.1_37525001_2 - 0.042 13.1 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GRIP PF01465.18 001309405.1_37525001_2 - 0.12 12.2 0.1 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 GRIP domain ELO PF01151.16 001279460.1_37523001_3 - 1.7e-63 214.3 32.0 2.2e-63 214.0 32.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Folate_rec PF03024.12 001279741.1_37525001_1 - 8.7e-52 175.3 16.0 1.2e-51 174.9 16.0 1.2 1 0 0 1 1 1 1 Folate receptor family BNR_2 PF13088.4 001293135.1_37523001_1 - 2.5e-43 148.3 0.0 3.1e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.4 001293135.1_37523001_1 - 3.4e-09 36.3 0.0 5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.18 001293135.1_37523001_1 - 0.00027 20.3 4.0 0.2 11.6 0.2 2.9 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_4 PF15892.3 001293135.1_37523001_1 - 0.027 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 BNR repeat-containing family member EF-hand_1 PF00036.30 001309837.1_12821001_1 - 8.2e-10 37.4 2.1 0.00058 19.1 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 001309837.1_12821001_1 - 1.9e-09 37.7 0.2 2.8e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.4 001309837.1_12821001_1 - 1.1e-08 34.1 0.9 0.0025 17.2 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.4 001309837.1_12821001_1 - 1.8e-08 33.9 1.0 1.1e-07 31.4 0.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001309837.1_12821001_1 - 9e-08 31.3 0.3 0.0012 18.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain DUF1641 PF07849.9 001309837.1_12821001_1 - 0.024 14.3 0.0 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) SPARC_Ca_bdg PF10591.7 001309837.1_12821001_1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region p450 PF00067.20 001290671.1_11124001_1 - 4.2e-110 368.5 0.1 5.3e-110 368.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec8_exocyst PF04048.12 001290671.1_11124001_1 - 0.058 13.2 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF3600 PF12207.6 001290671.1_11124001_1 - 0.069 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) EF-hand_1 PF00036.30 001309839.1_12821001_1 - 5e-13 47.4 5.8 3e-07 29.4 1.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 001309839.1_12821001_1 - 8e-12 45.3 1.2 1.2e-11 44.8 1.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.4 001309839.1_12821001_1 - 3.3e-11 42.0 2.4 2.2e-06 27.0 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.4 001309839.1_12821001_1 - 1.2e-09 37.1 6.2 4e-05 22.8 0.9 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.4 001309839.1_12821001_1 - 8.4e-06 25.3 1.5 2e-05 24.1 0.4 1.9 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001309839.1_12821001_1 - 0.0062 16.7 0.1 0.011 15.9 0.1 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Skp1 PF01466.17 001309839.1_12821001_1 - 0.068 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain EFhand_Ca_insen PF08726.8 001309839.1_12821001_1 - 0.12 12.3 0.1 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand RNase_H PF00075.22 001285516.1_22323001_1 - 7.4e-46 155.8 0.0 1.1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285516.1_22323001_1 - 2.6e-06 27.5 2.9 5.5e-06 26.5 2.9 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285516.1_22323001_1 - 5.5e-05 22.7 0.0 0.00017 21.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like Orn_Arg_deC_N PF02784.14 001291600.1_22325001_1 - 2.5e-62 210.4 0.0 3.2e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291600.1_22325001_1 - 5.9e-22 77.7 0.0 1.2e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001293745.1_22323001_2 - 1.2e-62 211.5 0.0 1.4e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293745.1_22323001_2 - 2.2e-14 53.3 0.0 3.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293745.1_22323001_2 - 0.043 13.1 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Transthyretin PF00576.19 001291402.1_22322001_1 - 1.9e-20 73.4 0.1 2.8e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family Glyco_hydro_9 PF00759.17 001292325.1_08123001_1 - 1.8 7.7 5.0 2.5 7.3 5.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 RRM_1 PF00076.20 001292325.1_08123001_3 - 3.4e-23 81.1 0.0 4.7e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001292325.1_08123001_3 - 0.0055 16.7 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.3 001292325.1_08123001_3 - 0.058 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif HEXIM PF15313.4 001245403.1_49923001_1 - 2.2e-55 186.6 3.8 3.7e-55 185.9 3.8 1.4 1 0 0 1 1 1 1 Hexamethylene bis-acetamide-inducible protein Trypan_PARP PF05887.9 001245403.1_49923001_1 - 0.055 13.4 19.6 0.12 12.3 19.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) bZIP_2 PF07716.13 001245403.1_49923001_1 - 0.16 11.9 13.2 0.68 9.9 3.5 3.3 2 0 0 2 2 2 0 Basic region leucine zipper CAGE1 PF15066.4 001245403.1_49923001_1 - 8.2 4.8 9.7 0.51 8.8 4.8 1.4 2 0 0 2 2 2 0 Cancer-associated gene protein 1 family Filament PF00038.19 001293122.1_02224001_1 - 3.2e-94 315.9 30.7 3.7e-94 315.7 30.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.3 001293122.1_02224001_1 - 7.1e-06 26.2 18.0 7.1e-06 26.2 18.0 2.3 2 1 0 2 2 1 1 Keratin type II head Spc7 PF08317.9 001293122.1_02224001_1 - 1.9e-05 23.6 22.7 0.0052 15.6 7.2 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.10 001293122.1_02224001_1 - 4.2e-05 23.5 20.5 0.005 16.8 4.2 2.6 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.9 001293122.1_02224001_1 - 5.1e-05 23.4 22.4 0.00016 21.8 3.7 3.1 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.7 001293122.1_02224001_1 - 0.0011 18.4 20.7 0.03 13.7 7.4 2.3 2 0 0 2 2 2 2 Golgin subfamily A member 5 DivIC PF04977.13 001293122.1_02224001_1 - 0.0032 17.1 13.7 0.089 12.4 0.4 3.6 2 1 1 3 3 3 2 Septum formation initiator CENP-F_leu_zip PF10473.7 001293122.1_02224001_1 - 0.0045 16.9 27.5 0.097 12.6 8.8 3.2 2 2 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1192 PF06698.9 001293122.1_02224001_1 - 0.022 14.7 5.4 0.38 10.7 1.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) BRE1 PF08647.9 001293122.1_02224001_1 - 0.028 14.4 21.8 0.046 13.7 1.1 3.6 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4793 PF16041.3 001293122.1_02224001_1 - 0.034 14.2 0.5 0.24 11.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4793) COG2 PF06148.9 001293122.1_02224001_1 - 0.057 13.4 11.4 0.66 9.9 0.8 3.6 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.20 001293122.1_02224001_1 - 0.1 12.7 15.6 1.3 9.2 3.6 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.10 001293122.1_02224001_1 - 0.12 12.3 0.1 1.7 8.5 0.0 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.9 001293122.1_02224001_1 - 0.2 12.1 9.8 1 9.8 1.3 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal IFT20 PF14931.4 001293122.1_02224001_1 - 0.24 11.5 10.8 4.7 7.3 4.6 2.7 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF3450 PF11932.6 001293122.1_02224001_1 - 0.26 10.4 17.3 0.032 13.4 3.0 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.4 001293122.1_02224001_1 - 0.29 10.3 10.5 1.6 7.9 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.9 001293122.1_02224001_1 - 0.31 10.8 16.3 0.045 13.6 3.6 2.3 2 0 0 2 2 2 0 Spc19 KxDL PF10241.7 001293122.1_02224001_1 - 0.33 11.1 3.3 0.18 12.0 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein APG6 PF04111.10 001293122.1_02224001_1 - 0.39 9.9 26.5 0.41 9.8 8.5 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 GIT_CC PF16559.3 001293122.1_02224001_1 - 0.51 10.3 10.3 20 5.2 0.4 4.3 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Alanine_zipper PF11839.6 001293122.1_02224001_1 - 0.54 10.4 8.4 0.39 10.9 4.6 2.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein ADIP PF11559.6 001293122.1_02224001_1 - 0.99 9.3 15.9 0.62 10.0 5.3 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding MscS_porin PF12795.5 001293122.1_02224001_1 - 1.1 8.6 9.1 0.1 12.0 1.9 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TMF_TATA_bd PF12325.6 001293122.1_02224001_1 - 1.4 9.0 19.2 4.6 7.4 3.9 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Bacillus_HBL PF05791.9 001293122.1_02224001_1 - 1.5 8.4 7.5 0.88 9.1 0.3 2.8 3 1 0 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.10 001293122.1_02224001_1 - 1.7 8.5 8.2 1.5 8.7 0.6 2.9 2 1 1 3 3 3 0 Laminin Domain II SOGA PF11365.6 001293122.1_02224001_1 - 2 9.5 11.3 8.6 7.4 0.1 3.0 3 0 0 3 3 2 0 Protein SOGA Tma16 PF11176.6 001293122.1_02224001_1 - 2.9 7.6 12.2 0.048 13.4 3.9 2.2 2 1 1 3 3 3 0 Translation machinery-associated protein 16 Jnk-SapK_ap_N PF09744.7 001293122.1_02224001_1 - 2.9 8.0 25.8 0.58 10.2 5.4 3.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF342 PF03961.11 001293122.1_02224001_1 - 3.5 6.0 15.6 1.3 7.5 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Spc24 PF08286.9 001293122.1_02224001_1 - 3.6 7.7 13.0 1.4 9.1 1.6 3.1 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 JIP_LZII PF16471.3 001293122.1_02224001_1 - 5 7.2 14.1 6.3 6.9 0.9 4.3 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.10 001293122.1_02224001_1 - 5.7 6.8 8.1 3.9 7.3 0.4 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.10 001293122.1_02224001_1 - 6.1 7.2 25.5 5.1 7.5 3.9 4.2 3 1 0 3 3 3 0 Cell division protein ZapB DUF4140 PF13600.4 001293122.1_02224001_1 - 7.7 6.9 12.2 3 8.2 2.2 3.3 3 1 1 4 4 3 0 N-terminal domain of unknown function (DUF4140) DUF883 PF05957.11 001293122.1_02224001_1 - 8.2 6.9 11.9 7.6 7.1 3.5 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ERM PF00769.17 001293122.1_02224001_1 - 8.8 5.9 27.8 2.1 8.0 8.2 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Ald_Xan_dh_C2 PF02738.16 001282244.1_12029001_1 - 6.7e-189 628.7 0.2 8.7e-189 628.4 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001282244.1_12029001_1 - 4.1e-43 146.9 0.0 8.1e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.18 001282244.1_12029001_1 - 1.5e-31 108.0 0.4 4.1e-31 106.6 0.4 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001282244.1_12029001_1 - 2.1e-31 108.0 0.0 5.2e-30 103.5 0.0 2.7 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.20 001282244.1_12029001_1 - 1.3e-30 105.8 4.2 2.7e-30 104.8 4.2 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.25 001282244.1_12029001_1 - 1.5e-07 31.2 3.3 9.4e-07 28.6 0.0 2.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001282244.1_12029001_1 - 0.023 14.4 1.8 0.07 12.8 1.8 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Actin PF00022.17 001290670.1_11123001_1 - 2.1e-150 500.7 0.0 7e-150 499.0 0.0 1.7 1 1 0 1 1 1 1 Actin Hormone_2 PF00123.18 001286848.1_01522001_2 - 2.2e-45 152.1 3.9 1.4e-14 53.6 0.1 3.6 3 0 0 3 3 3 3 Peptide hormone Lipoprotein_10 PF03202.11 001286848.1_01522001_2 - 0.0021 18.4 5.7 3.2 8.1 0.1 3.7 2 2 2 4 4 4 2 Putative mycoplasma lipoprotein, C-terminal region SBP_bac_8 PF13416.4 001286848.1_01522001_2 - 0.022 14.4 0.4 11 5.7 0.0 2.9 2 1 0 3 3 3 0 Bacterial extracellular solute-binding protein Hormone_1 PF00103.18 001286848.1_01522001_2 - 0.13 11.9 0.5 1.2 8.7 0.1 2.1 1 1 1 2 2 2 0 Somatotropin hormone family Thioredoxin PF00085.18 001281553.1_30922001_3 - 4.4e-30 103.6 0.8 5.7e-30 103.2 0.8 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.4 001281553.1_30922001_3 - 0.00011 22.4 0.1 0.00018 21.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.4 001281553.1_30922001_3 - 0.0013 18.7 0.1 0.0022 18.0 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.4 001281553.1_30922001_3 - 0.0049 17.2 0.5 0.016 15.5 0.5 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.4 001281553.1_30922001_3 - 0.0063 16.2 0.0 0.0092 15.6 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.11 001281553.1_30922001_3 - 0.0091 15.2 0.2 0.012 14.8 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.19 001281553.1_30922001_3 - 0.011 15.5 0.2 0.016 15.0 0.2 1.2 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.22 001281553.1_30922001_3 - 0.011 15.7 0.6 0.021 14.9 0.6 1.4 1 0 0 1 1 1 0 Glutaredoxin DIM1 PF02966.14 001281553.1_30922001_3 - 0.068 12.8 0.1 0.089 12.4 0.1 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 PAS_3 PF08447.10 001281961.1_22326001_1 - 6e-19 68.0 0.1 1.4e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001281961.1_22326001_1 - 1e-14 54.4 1.8 6.5e-11 42.2 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS PF00989.23 001281961.1_22326001_1 - 6.2e-13 48.6 2.4 1.2e-11 44.4 0.0 3.0 3 0 0 3 3 3 1 PAS fold HLH PF00010.24 001281961.1_22326001_1 - 1.8e-05 24.4 0.1 4.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.8 001281961.1_22326001_1 - 0.0022 18.1 0.1 0.089 12.9 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.5 001281961.1_22326001_1 - 0.0088 16.2 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 1 PAS domain Hormone_1 PF00103.18 001281556.1_30923001_2 - 3.9e-72 242.3 0.0 5e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Oest_recep PF02159.13 001282246.1_12024001_2 - 4.2e-68 228.0 9.3 4.2e-68 228.0 9.3 1.9 2 0 0 2 2 2 1 Oestrogen receptor Hormone_recep PF00104.28 001282246.1_12024001_2 - 1.2e-34 119.6 1.4 1.9e-34 118.9 1.4 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001282246.1_12024001_2 - 1.5e-31 108.5 13.9 2.7e-31 107.7 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ESR1_C PF12743.5 001282246.1_12024001_2 - 1.4e-20 72.6 1.9 4.5e-20 71.0 1.9 2.0 1 0 0 1 1 1 1 Oestrogen-type nuclear receptor final C-terminal PAS_3 PF08447.10 001281960.1_22325001_1 - 3.4e-24 84.8 0.0 2.5e-18 66.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001281960.1_22325001_1 - 7.3e-22 77.5 0.1 1.1e-19 70.5 0.3 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.23 001281960.1_22325001_1 - 4.9e-18 65.1 0.1 7.9e-10 38.6 0.0 3.3 3 1 0 3 3 3 2 PAS fold HLH PF00010.24 001281960.1_22325001_1 - 2.5e-15 56.0 1.0 9.2e-15 54.2 1.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001281960.1_22325001_1 - 5.8e-09 36.0 0.0 4e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001281960.1_22325001_1 - 0.0009 19.3 0.0 0.66 10.1 0.0 2.8 3 0 0 3 3 3 2 PAS fold PRAS PF15798.3 001281960.1_22325001_1 - 0.038 14.4 0.2 0.093 13.2 0.2 1.6 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 Catalase PF00199.17 001281560.1_30925001_2 - 6.7e-196 650.7 0.0 8.5e-196 650.4 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.10 001281560.1_30925001_2 - 8.5e-20 70.6 1.0 1.8e-19 69.5 0.4 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive UBA_4 PF14555.4 001292132.1_08124001_3 - 5.7e-11 41.9 0.2 1.3e-10 40.7 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.18 001292132.1_08124001_3 - 6e-05 23.0 0.2 0.00022 21.2 0.1 2.0 2 0 0 2 2 2 1 UBX domain DUF1682 PF07946.12 001292132.1_08124001_3 - 0.00031 19.9 6.4 0.00045 19.4 6.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4253 PF14062.4 001292132.1_08124001_3 - 0.14 12.2 0.1 1 9.4 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4253) Selenoprotein_S PF06936.9 001292132.1_08124001_3 - 0.49 10.1 8.7 0.82 9.3 8.7 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) CDC45 PF02724.12 001292132.1_08124001_3 - 8.3 4.4 9.6 12 3.9 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Cyt_bd_oxida_II PF02322.13 001281546.1_30926001_2 - 0.13 11.5 9.6 0.18 11.0 9.6 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II FOXP-CC PF16159.3 001281546.1_30926001_3 - 4.2e-35 120.0 4.6 4.2e-35 120.0 4.6 4.6 2 1 1 3 3 1 1 FOXP coiled-coil domain Forkhead PF00250.16 001281546.1_30926001_3 - 4.2e-28 97.4 0.2 1.4e-27 95.7 0.2 1.9 1 0 0 1 1 1 1 Forkhead domain Presenilin PF01080.15 001281546.1_30926001_3 - 0.11 11.0 22.1 0.25 9.9 22.1 1.6 1 0 0 1 1 1 0 Presenilin Draxin PF15550.4 001281546.1_30926001_3 - 0.46 10.2 19.4 0.12 12.1 14.2 2.3 2 0 0 2 2 2 0 Draxin Plasmodium_Vir PF05795.9 001281546.1_30926001_3 - 0.65 9.2 10.2 0.93 8.7 8.6 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein RR_TM4-6 PF06459.10 001281546.1_30926001_3 - 2.1 8.0 23.7 4.6 6.9 23.7 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.6 001281546.1_30926001_3 - 2.3 6.8 26.8 5.2 5.7 26.8 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter hDGE_amylase PF14701.4 001281546.1_30926001_3 - 4.2 6.2 21.5 8.4 5.2 21.5 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain CobT PF06213.10 001281546.1_30926001_3 - 4.4 6.5 32.3 7.2 5.8 32.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Isy1 PF06246.10 001281546.1_30926001_3 - 4.8 6.5 27.0 8.9 5.7 27.0 1.5 1 0 0 1 1 1 0 Isy1-like splicing family DUF2347 PF09804.7 001281546.1_30926001_3 - 5.5 6.3 15.4 11 5.3 15.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) TT_ORF1 PF02956.12 001281546.1_30926001_3 - 7 5.1 24.1 11 4.4 24.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 SID-1_RNA_chan PF13965.4 001281546.1_30926001_3 - 7.3 4.8 10.9 11 4.2 10.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Membralin PF09746.7 001281546.1_30926001_3 - 8.6 5.2 15.8 18 4.1 15.8 1.5 1 0 0 1 1 1 0 Tumour-associated protein Ald_Xan_dh_C2 PF02738.16 001281550.1_30928001_1 - 3.3e-194 646.2 0.0 4.1e-194 645.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001281550.1_30928001_1 - 8.2e-44 149.2 0.0 1.7e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.18 001281550.1_30928001_1 - 1.4e-29 101.7 0.7 3.9e-29 100.3 0.7 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.20 001281550.1_30928001_1 - 1e-28 99.8 1.5 2.2e-28 98.7 1.5 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001281550.1_30928001_1 - 1.1e-28 99.3 0.0 4.2e-27 94.2 0.0 2.7 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001281550.1_30928001_1 - 9.2e-11 41.4 0.6 2.3e-09 36.9 0.1 2.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Ald_Xan_dh_C2 PF02738.16 001282245.1_12029001_1 - 2.4e-191 636.8 0.0 3e-191 636.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001282245.1_12029001_1 - 1.2e-43 148.6 0.0 2.4e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001282245.1_12029001_1 - 2e-34 118.1 2.3 4.8e-34 116.9 2.3 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001282245.1_12029001_1 - 1.5e-31 108.5 0.0 1.4e-30 105.3 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.18 001282245.1_12029001_1 - 3e-30 103.8 2.3 9.1e-30 102.3 2.3 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.25 001282245.1_12029001_1 - 4.7e-05 23.1 1.0 4.7e-05 23.1 1.0 3.5 4 0 0 4 4 4 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.4 001282245.1_12029001_1 - 0.89 9.5 3.6 1 9.3 0.1 2.8 2 1 1 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain IRF-3 PF10401.7 001310369.1_02125001_2 - 3.4e-66 222.3 0.1 4.7e-66 221.9 0.1 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.15 001310369.1_02125001_2 - 4.8e-41 139.2 0.5 7.8e-41 138.5 0.5 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.12 001310369.1_02125001_2 - 0.00052 20.1 0.0 0.0009 19.4 0.0 1.2 1 0 0 1 1 1 1 MH2 domain SCF PF02404.13 001297464.1_43023001_3 - 1.2e-12 47.7 0.4 1.7e-12 47.1 0.4 1.4 1 1 0 1 1 1 1 Stem cell factor BatD PF13584.4 001297464.1_43023001_3 - 0.0075 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Oxygen tolerance Gastrin PF00918.15 001309836.1_12822001_3 - 2.8e-37 128.4 0.0 3.3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Gastrin/cholecystokinin family Acyltransferase PF01553.19 001302696.1_52322001_1 - 2.9e-08 33.3 0.0 5.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.11 001302696.1_52322001_1 - 1.8e-06 27.0 0.1 3e-06 26.2 0.1 1.5 1 1 0 1 1 1 1 Diacylglycerol acyltransferase PAS_3 PF08447.10 001302365.1_41627001_1 - 6e-24 84.0 0.0 3.3e-18 65.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001302365.1_41627001_1 - 1.4e-21 76.6 0.1 1.5e-19 70.1 0.3 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.23 001302365.1_41627001_1 - 2.4e-17 62.8 0.1 2.4e-09 37.0 0.0 3.2 3 1 0 3 3 3 2 PAS fold HLH PF00010.24 001302365.1_41627001_1 - 6.1e-15 54.8 1.5 1.2e-14 53.9 1.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001302365.1_41627001_1 - 1.1e-08 35.1 0.0 5.3e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001302365.1_41627001_1 - 0.002 18.2 0.0 0.86 9.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold Glycolytic PF00274.17 001297481.1_43023001_1 - 1.9e-176 585.8 0.0 2.1e-176 585.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Globin PF00042.20 001302369.1_41022001_1 - 6.3e-27 94.2 0.0 8.7e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Globin ATP-gua_Ptrans PF00217.17 001297484.1_43024001_3 - 4.3e-93 311.3 0.0 5.7e-93 310.9 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.13 001297484.1_43024001_3 - 7.4e-34 115.9 0.0 1.2e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Tubulin PF00091.23 001303301.1_36024001_3 - 2.4e-68 230.1 0.0 3.8e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001303301.1_36024001_3 - 1.8e-42 144.4 0.1 3e-42 143.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001303301.1_36024001_3 - 7.3e-07 29.4 0.0 1.9e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001303301.1_36024001_3 - 0.015 14.8 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.4 001303301.1_36024001_3 - 0.032 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin like EF-hand_1 PF00036.30 001309835.1_12821001_1 - 3e-12 45.0 4.7 6.5e-07 28.3 1.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 001309835.1_12821001_1 - 1.1e-11 44.9 0.2 1.5e-11 44.5 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.4 001309835.1_12821001_1 - 1.9e-10 39.7 1.1 3.4e-06 26.4 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.4 001309835.1_12821001_1 - 8.4e-10 37.6 4.4 4e-05 22.8 0.9 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.4 001309835.1_12821001_1 - 7.9e-08 31.8 1.2 1.8e-07 30.7 0.5 1.9 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001309835.1_12821001_1 - 0.029 14.5 0.0 0.048 13.8 0.0 1.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region zf-C4 PF00105.16 001294215.1_15724001_1 - 6.8e-30 103.2 16.6 1.5e-29 102.1 16.6 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001294215.1_15724001_1 - 7.5e-21 74.5 0.3 2.9e-20 72.6 0.1 1.9 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor AAA PF00004.27 001293048.1_24024001_2 - 2.6e-26 92.5 0.0 9e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 001293048.1_24024001_2 - 3.6e-05 24.1 0.0 0.00011 22.6 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.12 001293048.1_24024001_2 - 0.00014 21.7 0.0 0.00043 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.10 001293048.1_24024001_2 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293048.1_24024001_2 - 0.0031 16.4 0.0 0.0057 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293048.1_24024001_2 - 0.0036 17.0 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293048.1_24024001_2 - 0.004 17.2 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.4 001293048.1_24024001_2 - 0.0075 16.4 1.3 0.017 15.3 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.4 001293048.1_24024001_2 - 0.0086 16.5 0.7 0.03 14.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.9 001293048.1_24024001_2 - 0.012 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.19 001293048.1_24024001_2 - 0.013 14.7 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.11 001293048.1_24024001_2 - 0.02 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.14 001293048.1_24024001_2 - 0.022 14.1 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein RILP PF11461.6 001293048.1_24024001_2 - 0.034 14.2 3.4 0.082 13.0 3.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293048.1_24024001_2 - 0.037 13.6 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.4 001293048.1_24024001_2 - 0.055 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.4 001293048.1_24024001_2 - 0.072 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.15 001293048.1_24024001_2 - 0.075 12.0 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.15 001293048.1_24024001_2 - 0.077 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.4 001293048.1_24024001_2 - 0.1 12.0 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.4 001293048.1_24024001_2 - 0.13 11.9 0.4 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain SlyX PF04102.10 001293048.1_24024001_2 - 0.37 11.3 2.6 1.1 9.8 2.6 1.8 1 0 0 1 1 1 0 SlyX Actin PF00022.17 001297475.1_43024001_2 - 1.2e-150 501.6 0.0 2.9e-150 500.3 0.0 1.6 1 1 0 1 1 1 1 Actin 7tm_1 PF00001.19 001302370.1_35623001_1 - 4.1e-71 239.2 4.2 4.8e-71 239.0 4.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001302370.1_35623001_1 - 1.2e-12 47.6 10.1 1.6e-06 27.6 7.1 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001302370.1_35623001_1 - 1.3e-06 28.2 8.9 9.2e-06 25.4 3.0 2.1 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001302370.1_35623001_1 - 0.0012 18.1 12.0 0.002 17.4 7.5 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx AAA PF00004.27 001293054.1_44623001_3 - 5e-43 146.5 0.0 1.3e-42 145.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293054.1_44623001_3 - 2.4e-07 30.9 0.0 5.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293054.1_44623001_3 - 3.1e-06 27.1 0.0 1.7e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293054.1_44623001_3 - 4.4e-06 27.0 0.2 7.9e-05 23.0 0.0 2.7 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293054.1_44623001_3 - 3.4e-05 24.0 0.9 0.0056 16.8 0.2 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293054.1_44623001_3 - 0.0001 21.6 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293054.1_44623001_3 - 0.0016 17.3 0.0 0.0034 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.4 001293054.1_44623001_3 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.15 001293054.1_44623001_3 - 0.0019 17.8 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.4 001293054.1_44623001_3 - 0.0028 18.0 0.2 0.021 15.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.19 001293054.1_44623001_3 - 0.0067 15.7 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.9 001293054.1_44623001_3 - 0.0067 16.1 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.11 001293054.1_44623001_3 - 0.0092 15.2 0.0 0.025 13.8 0.0 1.7 1 0 0 1 1 1 1 KaiC PhoH PF02562.14 001293054.1_44623001_3 - 0.011 15.1 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein RILP PF11461.6 001293054.1_44623001_3 - 0.02 15.0 3.4 0.054 13.6 3.4 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_28 PF13521.4 001293054.1_44623001_3 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.24 001293054.1_44623001_3 - 0.025 14.1 0.1 0.1 12.1 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293054.1_44623001_3 - 0.029 14.0 0.0 0.069 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.15 001293054.1_44623001_3 - 0.045 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293054.1_44623001_3 - 0.05 12.6 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.11 001293054.1_44623001_3 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.4 001293054.1_44623001_3 - 0.056 12.9 0.0 0.17 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.4 001293054.1_44623001_3 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.4 001293054.1_44623001_3 - 0.064 12.8 0.5 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.20 001293054.1_44623001_3 - 0.068 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.4 001293054.1_44623001_3 - 0.084 13.2 0.6 0.5 10.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.10 001293054.1_44623001_3 - 0.11 11.6 0.0 0.32 10.1 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.4 001293054.1_44623001_3 - 0.13 12.5 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain SlyX PF04102.10 001293054.1_44623001_3 - 0.16 12.5 2.3 0.54 10.8 2.3 2.0 1 0 0 1 1 1 0 SlyX Laminin_II PF06009.10 001293054.1_44623001_3 - 0.24 11.3 3.7 1.3 8.9 1.0 2.7 3 0 0 3 3 3 0 Laminin Domain II MscS_porin PF12795.5 001293054.1_44623001_3 - 7.4 5.9 12.7 12 5.2 12.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain IRF PF00605.15 001303381.1_27624001_2 - 1.9e-37 127.6 1.4 3.3e-37 126.8 1.4 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Ldh_1_N PF00056.21 001303292.1_36023001_3 - 1.7e-48 164.2 1.2 2.8e-48 163.5 1.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001303292.1_36023001_3 - 9.7e-26 90.5 0.2 2.1e-25 89.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.14 001303292.1_36023001_3 - 0.018 14.5 0.8 0.054 12.9 0.1 2.1 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Tubulin PF00091.23 001303286.1_36024001_3 - 7.2e-70 235.1 0.0 1.1e-69 234.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001303286.1_36024001_3 - 7.8e-43 145.6 0.1 1.2e-42 145.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001303286.1_36024001_3 - 1.6e-05 25.0 0.0 3.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001303286.1_36024001_3 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.4 001303286.1_36024001_3 - 0.018 14.1 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Hormone_recep PF00104.28 001286330.1_25029001_3 - 3e-33 115.0 3.4 4.7e-33 114.4 3.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001286330.1_25029001_3 - 1.7e-30 105.1 13.5 1.7e-30 105.1 13.5 2.1 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) ERbeta_N PF12497.6 001286330.1_25029001_3 - 4.3e-28 97.2 3.7 7.9e-28 96.4 3.7 1.4 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.28 001286336.1_25026001_1 - 6.8e-33 113.9 3.8 1.5e-32 112.8 3.8 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001286336.1_25026001_1 - 2.4e-24 85.4 16.5 2.4e-24 85.4 16.5 2.3 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) CRAL_TRIO PF00650.18 001286336.1_25026001_1 - 0.035 13.7 0.3 0.061 12.9 0.3 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain PAS_11 PF14598.4 001286316.1_25026001_1 - 1e-21 77.0 4.3 6.1e-21 74.5 0.0 4.0 3 1 1 4 4 4 1 PAS domain PAS_3 PF08447.10 001286316.1_25026001_1 - 8e-19 67.6 0.6 1.7e-15 56.9 0.1 3.0 3 0 0 3 3 3 2 PAS fold HLH PF00010.24 001286316.1_25026001_1 - 4.6e-10 39.2 0.7 1.2e-09 37.9 0.7 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.23 001286316.1_25026001_1 - 1.5e-07 31.3 11.3 7.3e-07 29.1 0.0 4.7 4 2 0 4 4 4 2 PAS fold PAS_9 PF13426.5 001286316.1_25026001_1 - 0.0015 18.6 0.5 0.012 15.7 0.0 2.9 3 0 0 3 3 3 1 PAS domain RNA_pol_Rpb4 PF03874.14 001286316.1_25026001_1 - 0.019 15.1 1.0 0.019 15.1 1.0 4.2 3 2 1 4 4 4 0 RNA polymerase Rpb4 PAS_11 PF14598.4 001286304.1_25025001_3 - 2.9e-26 91.7 0.4 2.6e-22 78.9 0.2 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 001286304.1_25025001_3 - 3.3e-21 75.3 0.0 1.5e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.10 001286304.1_25025001_3 - 1e-19 70.5 0.1 3.1e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 PAS fold HLH PF00010.24 001286304.1_25025001_3 - 2.3e-17 62.5 0.8 4.3e-17 61.7 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001286304.1_25025001_3 - 9.6e-09 35.3 0.0 1.1e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001286304.1_25025001_3 - 0.00051 20.1 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.9 001286304.1_25025001_3 - 0.0096 16.4 0.0 0.093 13.3 0.0 2.2 2 0 0 2 2 2 1 PAS fold bZIP_1 PF00170.19 001286320.1_25024001_3 - 1.4e-06 28.2 13.4 1.4e-06 28.2 13.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.15 001286320.1_25024001_3 - 0.00081 19.7 10.0 0.0017 18.7 10.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.13 001286320.1_25024001_3 - 0.0016 18.4 14.1 0.0016 18.4 14.1 1.9 2 0 0 2 2 2 1 Basic region leucine zipper Abhydro_lipase PF04083.14 001286320.1_25024001_3 - 0.11 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Casc1_N PF15927.3 001286320.1_25024001_3 - 1.7 8.2 10.7 2.7 7.5 10.7 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus EF-1_beta_acid PF10587.7 001286320.1_25024001_3 - 3.9 7.9 7.3 9 6.7 7.3 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Hormone_recep PF00104.28 001286331.1_25026001_2 - 5.6e-32 110.9 5.7 9.7e-32 110.1 5.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001286331.1_25026001_2 - 3.4e-27 94.6 14.0 1.1e-26 92.9 14.0 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Androgen_recep PF02166.14 001286331.1_25026001_2 - 2.6e-05 23.1 0.3 5.3e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 Androgen receptor 7tm_1 PF00001.19 001286302.1_25023001_3 - 3e-40 138.0 20.6 5.3e-40 137.2 20.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001286302.1_25023001_3 - 0.00036 19.9 21.6 0.00055 19.3 21.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_2 PF00002.22 001286300.1_25023001_2 - 6.7e-76 254.7 18.2 9.4e-76 254.2 18.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.20 001286300.1_25023001_2 - 2.6e-16 59.5 2.0 5.5e-16 58.5 2.0 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF4083 PF13314.4 001286300.1_25023001_2 - 1.1 9.1 4.5 8 6.4 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) NPP PF08384.8 001286333.1_25022001_1 - 7.3e-26 89.8 5.6 1.2e-25 89.1 5.6 1.4 1 0 0 1 1 1 1 Pro-opiomelanocortin, N-terminal region Op_neuropeptide PF08035.9 001286333.1_25022001_1 - 3.5e-20 71.4 0.1 5.8e-20 70.7 0.1 1.4 1 0 0 1 1 1 1 Opioids neuropeptide ACTH_domain PF00976.16 001286333.1_25022001_1 - 2.2e-17 62.4 17.9 3.8e-09 36.1 3.8 2.2 2 0 0 2 2 2 2 Corticotropin ACTH domain ACTH_domain PF00976.16 001286282.1_25023001_1 - 2.2e-25 87.9 30.7 7.1e-11 41.6 3.1 3.3 3 0 0 3 3 3 3 Corticotropin ACTH domain NPP PF08384.8 001286282.1_25023001_1 - 2.2e-06 27.5 1.3 4.7e-06 26.4 1.3 1.6 1 0 0 1 1 1 1 Pro-opiomelanocortin, N-terminal region Op_neuropeptide PF08035.9 001286282.1_25023001_1 - 0.0016 18.1 0.2 0.0016 18.1 0.2 1.8 2 0 0 2 2 2 1 Opioids neuropeptide Hormone_2 PF00123.18 001286323.1_25022001_1 - 1.5e-18 66.3 1.1 3.1e-12 46.1 0.2 2.4 2 0 0 2 2 2 2 Peptide hormone 7tm_2 PF00002.22 001286313.1_25023001_2 - 1.1e-77 260.5 22.7 1.4e-77 260.1 22.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.20 001286313.1_25023001_2 - 3.1e-17 62.5 2.9 6.9e-17 61.4 2.9 1.6 1 0 0 1 1 1 1 Hormone receptor domain PetL PF05115.12 001286313.1_25023001_2 - 3 7.8 8.2 0.16 11.8 0.5 2.7 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) DUF2976 PF11190.6 001286313.1_25023001_2 - 7 6.4 7.0 23 4.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Homeobox PF00046.27 001286284.1_25024001_3 - 2.6e-20 71.9 2.4 5.6e-20 70.8 2.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001286284.1_25024001_3 - 0.03 14.1 0.1 0.03 14.1 0.1 2.6 3 0 0 3 3 3 0 Homeobox KN domain GCR PF02155.13 001286286.1_25026001_1 - 1.5e-70 238.0 12.3 2.1e-70 237.5 12.3 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor Hormone_recep PF00104.28 001286286.1_25026001_1 - 2.4e-30 105.5 3.7 4e-30 104.8 3.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001286286.1_25026001_1 - 1.6e-27 95.6 13.2 1.6e-27 95.6 13.2 2.1 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) zf-P11 PF03854.12 001286286.1_25026001_1 - 2.6 7.6 6.9 11 5.7 2.1 2.8 2 0 0 2 2 2 0 P-11 zinc finger Homeobox PF00046.27 001286290.1_25025001_2 - 3.2e-20 71.6 3.2 5.7e-20 70.7 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001286290.1_25025001_2 - 0.019 14.7 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Zona_pellucida PF00100.21 001315649.1_45026001_2 - 9.9e-42 143.3 9.8 9.9e-42 143.3 9.8 2.8 3 1 0 3 3 3 1 Zona pellucida-like domain C8 PF08742.9 001315649.1_45026001_2 - 1.5e-14 54.0 3.5 1.5e-14 54.0 3.5 3.6 3 0 0 3 3 3 1 C8 domain VWD PF00094.23 001315649.1_45026001_2 - 3.3e-07 30.6 6.4 6.5e-07 29.6 0.0 3.2 3 1 0 3 3 3 1 von Willebrand factor type D domain ecTbetaR2 PF08917.8 001315649.1_45026001_2 - 0.0053 16.5 0.1 0.0053 16.5 0.1 5.0 5 2 2 7 7 7 1 Transforming growth factor beta receptor 2 ectodomain XK-related PF09815.7 001032709.1_50025001_3 - 6.3e-85 285.0 25.0 6.3e-85 285.0 25.0 1.9 2 0 0 2 2 2 1 XK-related protein Glyco_transf_29 PF00777.16 001032760.1_50023001_1 - 1.4e-73 247.5 0.0 1.7e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Filament PF00038.19 001305599.1_50023001_1 - 8.7e-116 386.7 41.2 1.1e-115 386.5 41.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.12 001305599.1_50023001_1 - 1.1e-14 54.9 15.1 1.5e-14 54.5 10.1 2.3 2 0 0 2 2 2 1 Intermediate filament head (DNA binding) region Reo_sigmaC PF04582.10 001305599.1_50023001_1 - 0.00016 21.1 6.4 0.25 10.6 0.2 3.1 1 1 1 3 3 3 3 Reovirus sigma C capsid protein FAM184 PF15665.3 001305599.1_50023001_1 - 0.00026 20.7 34.0 0.013 15.2 1.1 3.4 1 1 2 3 3 3 3 Family with sequence similarity 184, A and B DUF3584 PF12128.6 001305599.1_50023001_1 - 0.0052 14.3 33.8 0.0094 13.4 14.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) KASH_CCD PF14662.4 001305599.1_50023001_1 - 0.0084 15.8 33.4 0.24 11.1 10.0 3.5 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.7 001305599.1_50023001_1 - 0.013 15.4 35.3 0.19 11.7 2.2 3.6 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4515 PF14988.4 001305599.1_50023001_1 - 0.014 15.1 35.1 0.087 12.5 16.3 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4515) Spc7 PF08317.9 001305599.1_50023001_1 - 0.02 13.7 35.5 0.55 8.9 5.3 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein IncA PF04156.12 001305599.1_50023001_1 - 0.023 14.3 39.0 0.42 10.2 13.7 3.7 1 1 3 4 4 4 0 IncA protein Prefoldin PF02996.15 001305599.1_50023001_1 - 0.039 13.7 0.9 0.039 13.7 0.9 5.9 4 1 0 4 4 3 0 Prefoldin subunit DUF1664 PF07889.10 001305599.1_50023001_1 - 0.096 12.6 19.7 0.21 11.5 2.4 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF4407 PF14362.4 001305599.1_50023001_1 - 0.12 11.6 27.3 0.26 10.5 12.6 2.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) KLRAQ PF10205.7 001305599.1_50023001_1 - 0.12 12.5 25.1 0.3 11.2 9.2 4.1 2 2 1 3 3 3 0 Predicted coiled-coil domain-containing protein APG6 PF04111.10 001305599.1_50023001_1 - 0.14 11.4 36.5 0.33 10.2 16.1 3.2 1 1 2 3 3 3 0 Autophagy protein Apg6 TolA_bind_tri PF16331.3 001305599.1_50023001_1 - 0.16 12.0 45.9 0.043 13.8 4.2 6.6 3 1 4 7 7 7 0 TolA binding protein trimerisation DUF972 PF06156.11 001305599.1_50023001_1 - 0.16 12.5 33.9 0.36 11.4 4.3 5.3 1 1 4 5 5 5 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.10 001305599.1_50023001_1 - 0.23 11.4 12.8 0.77 9.7 0.4 3.9 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.4 001305599.1_50023001_1 - 0.38 11.0 40.7 7.6 6.8 14.1 5.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4200) Jnk-SapK_ap_N PF09744.7 001305599.1_50023001_1 - 0.39 10.8 38.5 0.19 11.8 14.6 4.1 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 CENP-H PF05837.10 001305599.1_50023001_1 - 0.63 10.3 30.3 0.93 9.8 3.4 4.1 2 2 1 4 4 4 0 Centromere protein H (CENP-H) Macoilin PF09726.7 001305599.1_50023001_1 - 0.63 8.4 28.8 0.76 8.1 10.2 3.1 1 1 1 2 2 2 0 Transmembrane protein DUF812 PF05667.9 001305599.1_50023001_1 - 0.82 8.4 33.6 0.18 10.5 16.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.10 001305599.1_50023001_1 - 1 9.3 39.7 0.56 10.1 17.2 4.3 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein FlxA PF14282.4 001305599.1_50023001_1 - 1.1 9.2 26.0 1.9 8.4 2.3 4.1 1 1 2 3 3 3 0 FlxA-like protein ACR_tran PF00873.17 001305599.1_50023001_1 - 1.3 6.4 6.6 1.7 6.1 6.6 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family bZIP_1 PF00170.19 001305599.1_50023001_1 - 1.4 8.9 21.7 5.6 7.0 4.9 5.8 3 2 3 6 6 6 0 bZIP transcription factor WD40_alt PF14077.4 001305599.1_50023001_1 - 1.5 8.6 5.0 11 5.9 1.2 3.5 3 0 0 3 3 3 0 Alternative WD40 repeat motif WXG100 PF06013.10 001305599.1_50023001_1 - 1.7 8.8 16.3 4 7.6 5.0 4.1 3 1 1 4 4 4 0 Proteins of 100 residues with WXG DUF573 PF04504.12 001305599.1_50023001_1 - 2.8 8.5 6.8 1.5 9.4 0.8 3.1 3 1 0 3 3 2 0 Protein of unknown function, DUF573 LPP PF04728.11 001305599.1_50023001_1 - 3.3 8.0 15.6 2.5 8.4 1.2 5.1 4 2 1 5 5 5 0 Lipoprotein leucine-zipper DUF5082 PF16888.3 001305599.1_50023001_1 - 4.6 7.5 31.0 1.3 9.2 11.4 4.7 2 1 3 5 5 5 0 Domain of unknown function (DUF5082) Apo-CII PF05355.9 001032718.1_50021001_1 - 9.8e-09 35.1 0.3 1.2e-08 34.8 0.3 1.1 1 0 0 1 1 1 1 Apolipoprotein C-II zf-C4 PF00105.16 001097630.1_50023001_1 - 3.8e-28 97.6 16.5 6.6e-28 96.8 16.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001097630.1_50023001_1 - 2.2e-15 56.7 0.0 5.8e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PET PF06297.12 001245095.1_50024001_1 - 5.7e-36 122.6 0.3 9.6e-36 121.8 0.3 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.20 001245095.1_50024001_1 - 1.6e-24 85.7 57.0 9.7e-13 48.0 6.6 5.3 4 2 0 4 4 4 3 LIM domain SOCS PF12610.6 001122864.1_50025001_2 - 3.1e-14 53.0 0.1 3.1e-14 53.0 0.1 2.5 2 0 0 2 2 2 1 Suppressor of cytokine signalling SH2 PF00017.22 001122864.1_50025001_2 - 1.1e-09 38.1 0.1 2.4e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.14 001122864.1_50025001_2 - 2e-06 27.9 0.1 4.8e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 SOCS box DUF4668 PF15701.3 001122864.1_50025001_3 - 1.7 8.3 3.7 3.1 7.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Hemopexin PF00045.17 001032589.1_50024001_2 - 6.8e-30 102.6 8.7 0.00021 21.0 0.0 7.6 8 0 0 8 8 8 7 Hemopexin F5_F8_type_C PF00754.23 001032750.1_50029001_1 - 2.3e-55 186.0 4.2 1.1e-26 93.3 0.3 3.1 3 0 0 3 3 3 2 F5/8 type C domain Cu-oxidase_3 PF07732.13 001032750.1_50029001_1 - 1.3e-17 63.7 1.4 3.3e-09 36.7 0.0 4.9 5 0 0 5 5 5 3 Multicopper oxidase Cu-oxidase_2 PF07731.12 001032750.1_50029001_1 - 1.8e-10 40.6 7.6 0.00017 21.2 1.3 4.0 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.20 001032750.1_50029001_1 - 0.00053 20.0 0.0 1.2 9.1 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Aldedh PF00171.20 001160185.1_50024001_3 - 2.2e-179 596.7 0.0 2.6e-179 596.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IL15 PF02372.13 001033640.1_50022001_2 - 1.8e-07 31.1 1.5 9.6e-07 28.8 1.5 1.9 1 1 0 1 1 1 1 Interleukin 15 Orn_Arg_deC_N PF02784.14 001291659.1_54027001_1 - 9.4e-64 215.1 0.0 1.2e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291659.1_54027001_1 - 3.9e-22 78.3 0.0 6.9e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PH_12 PF16457.3 001245222.1_49923001_2 - 2.1e-19 70.2 0.7 4.5e-19 69.2 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain ZFYVE21_C PF16696.3 001245222.1_49923001_2 - 0.07 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus PH_12 PF16457.3 001245222.1_49923001_3 - 2.5e-11 44.1 0.0 3.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain zf-CCCH PF00642.22 001245241.2_49922001_3 - 8.8e-14 50.9 16.6 8.7e-07 28.6 2.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.20 001245241.2_49922001_3 - 1.1e-06 28.3 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.3 001245241.2_49922001_3 - 1.4e-06 28.9 1.3 0.041 14.4 0.1 2.4 2 0 0 2 2 2 2 Torus domain KMP11 PF03037.14 001245241.2_49922001_3 - 0.031 14.9 0.5 0.99 10.1 0.3 2.2 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Nup35_RRM_2 PF14605.4 001245241.2_49922001_3 - 0.061 13.2 0.0 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.3 001245241.2_49922001_3 - 0.19 11.8 5.4 2.4 8.3 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger containing family DUF543 PF04418.10 001245605.2_49922001_3 - 5.7e-23 80.6 0.8 9.3e-23 79.9 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF543) KRTAP PF11759.6 001245605.2_49922001_3 - 0.37 11.2 3.8 0.63 10.5 3.8 1.4 1 0 0 1 1 1 0 Keratin-associated matrix EF-hand_1 PF00036.30 001245865.2_49923001_2 - 1.4e-15 55.4 8.8 2.5e-08 32.8 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.4 001245865.2_49923001_2 - 1.7e-14 53.9 1.5 1.8e-13 50.6 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.4 001245865.2_49923001_2 - 7.4e-14 50.3 1.9 5.9e-08 31.9 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.4 001245865.2_49923001_2 - 9.6e-12 43.7 10.3 8.6e-06 24.9 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.4 001245865.2_49923001_2 - 2.1e-11 43.3 9.2 2.7e-09 36.5 0.4 4.1 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.4 001245865.2_49923001_2 - 0.0039 17.4 0.0 0.0095 16.1 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.5 001245865.2_49923001_2 - 0.024 14.4 0.1 0.059 13.2 0.1 1.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001245865.2_49923001_2 - 0.047 13.9 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Serpin PF00079.18 001245196.1_49924001_3 - 9.8e-115 383.6 1.6 1.1e-114 383.4 1.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Rsbr_N PF08678.8 001245196.1_49924001_3 - 0.12 12.3 0.9 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 Rsbr N terminal Ras PF00071.20 001245713.2_49923001_3 - 1.5e-59 200.1 0.1 1.9e-59 199.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001245713.2_49923001_3 - 3.3e-31 107.9 0.0 4.9e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001245713.2_49923001_3 - 9.9e-12 44.5 0.0 1.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001245713.2_49923001_3 - 0.00059 19.3 0.0 0.0066 15.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001245713.2_49923001_3 - 0.00098 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001245713.2_49923001_3 - 0.0024 17.7 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001245713.2_49923001_3 - 0.0071 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.15 001245713.2_49923001_3 - 0.048 13.3 0.0 0.69 9.5 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.27 001245713.2_49923001_3 - 0.12 12.7 0.0 0.4 11.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FAA_hydrolase PF01557.16 001245120.1_49922001_1 - 1.1e-27 97.0 0.0 1.5e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase PF01557.16 001245120.1_49922001_3 - 7.3e-27 94.3 0.0 9.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SPC12 PF06645.11 001245441.1_49923001_1 - 8.7e-30 102.5 0.7 8.7e-30 102.5 0.7 1.6 2 0 0 2 2 2 1 Microsomal signal peptidase 12 kDa subunit (SPC12) UCR_hinge PF02320.14 001245935.1_49922001_1 - 4.2e-24 84.4 8.0 4.2e-24 84.4 8.0 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Ribosomal_L22 PF00237.17 001076700.2_49922001_1 - 7.6e-43 145.0 0.1 1.2e-42 144.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Tom37 PF10568.7 001245401.1_49923001_2 - 2.9e-28 98.6 0.0 6.1e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.2 001245401.1_49923001_2 - 1.1e-23 83.7 0.0 2.4e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.2 001245401.1_49923001_2 - 2.2e-23 81.7 0.2 5.7e-23 80.4 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001245401.1_49923001_2 - 5.2e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Somatostatin PF03002.13 001245475.1_49922001_2 - 5.2e-12 45.4 7.8 1.1e-11 44.3 7.8 1.6 1 0 0 1 1 1 1 Somatostatin/Cortistatin family 7tm_1 PF00001.19 001310072.1_30523001_1 - 3.2e-40 137.9 18.3 4.3e-40 137.5 18.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001310072.1_30523001_1 - 7.4e-06 25.4 5.5 7.4e-06 25.4 5.5 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.7 001310072.1_30523001_1 - 0.00014 21.2 20.1 0.00029 20.2 20.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.11 001310072.1_30523001_1 - 0.004 16.2 11.7 0.016 14.2 0.9 2.1 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) zf-DHHC PF01529.18 001310072.1_30523001_1 - 3.7 7.5 18.1 0.75 9.8 4.5 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2569 PF10754.7 001310072.1_30523001_1 - 8.5 6.7 15.2 3.6 7.9 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) FOXP-CC PF16159.3 001310073.1_30525001_1 - 2e-35 121.1 4.2 2e-35 121.1 4.2 3.6 2 1 1 3 3 3 1 FOXP coiled-coil domain Forkhead PF00250.16 001310073.1_30525001_1 - 1.5e-27 95.6 0.1 4.1e-27 94.2 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain Bestrophin PF01062.19 001310073.1_30525001_1 - 0.18 11.0 0.0 0.18 11.0 0.0 2.5 3 0 0 3 3 3 0 Bestrophin, RFP-TM, chloride channel Orn_Arg_deC_N PF02784.14 001291662.1_44625001_2 - 5.3e-64 215.9 0.0 6.7e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291662.1_44625001_2 - 2.8e-22 78.8 0.0 5.7e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001293754.1_44623001_1 - 9.6e-61 205.2 0.0 1.2e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293754.1_44623001_1 - 4.6e-16 58.7 0.0 1.9e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain P5CR_dimer PF14748.4 001292083.1_44623001_3 - 3.2e-37 126.8 0.0 8.6e-37 125.4 0.0 1.8 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.15 001292083.1_44623001_3 - 6.4e-19 68.2 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.7 001292083.1_44623001_3 - 0.0045 16.7 0.2 0.0045 16.7 0.2 1.8 2 0 0 2 2 2 1 Rossmann-like domain ApbA PF02558.14 001292083.1_44623001_3 - 0.056 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.21 001292083.1_44623001_3 - 0.15 11.9 1.2 0.76 9.6 1.2 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.15 001292083.1_44623001_3 - 0.16 10.8 0.1 0.26 10.1 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase FOXP-CC PF16159.3 001315652.1_45025001_1 - 2e-35 121.1 4.2 2e-35 121.1 4.2 3.6 2 1 1 3 3 3 1 FOXP coiled-coil domain Forkhead PF00250.16 001315652.1_45025001_1 - 1.5e-27 95.6 0.1 4.1e-27 94.2 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain Leptin PF02024.13 001311192.1_03522001_1 - 1.5e-26 92.8 0.0 1.9e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Leptin Orn_Arg_deC_N PF02784.14 001291657.1_22225001_2 - 2.3e-62 210.5 0.0 2.9e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291657.1_22225001_2 - 5.4e-22 77.8 0.0 1.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AAA PF00004.27 001293050.1_22223001_1 - 4.6e-43 146.7 0.0 1.2e-42 145.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293050.1_22223001_1 - 2.1e-07 31.1 0.0 5.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293050.1_22223001_1 - 2.7e-06 27.3 0.0 1.5e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293050.1_22223001_1 - 3.8e-06 27.3 0.2 7.4e-05 23.1 0.0 2.7 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293050.1_22223001_1 - 3.3e-05 24.1 1.0 0.0052 16.9 0.2 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293050.1_22223001_1 - 9e-05 21.7 0.0 0.00018 20.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293050.1_22223001_1 - 0.0015 17.4 0.0 0.0031 16.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293050.1_22223001_1 - 0.0018 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293050.1_22223001_1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293050.1_22223001_1 - 0.0025 18.2 0.2 0.02 15.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.9 001293050.1_22223001_1 - 0.0061 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.19 001293050.1_22223001_1 - 0.0063 15.8 0.1 0.016 14.5 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.11 001293050.1_22223001_1 - 0.0082 15.4 0.0 0.023 13.9 0.0 1.7 1 0 0 1 1 1 1 KaiC PhoH PF02562.14 001293050.1_22223001_1 - 0.0089 15.4 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.4 001293050.1_22223001_1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293050.1_22223001_1 - 0.019 15.0 3.4 0.051 13.7 3.4 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293050.1_22223001_1 - 0.022 14.3 0.1 0.099 12.2 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293050.1_22223001_1 - 0.026 14.1 0.0 0.074 12.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain TsaE PF02367.15 001293050.1_22223001_1 - 0.041 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293050.1_22223001_1 - 0.046 12.7 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.11 001293050.1_22223001_1 - 0.05 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.4 001293050.1_22223001_1 - 0.05 13.0 0.0 0.16 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.4 001293050.1_22223001_1 - 0.053 13.1 0.3 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.4 001293050.1_22223001_1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001293050.1_22223001_1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.4 001293050.1_22223001_1 - 0.074 13.3 0.6 0.47 10.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.10 001293050.1_22223001_1 - 0.12 11.5 0.2 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.4 001293050.1_22223001_1 - 0.13 12.5 0.2 0.51 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain SlyX PF04102.10 001293050.1_22223001_1 - 0.14 12.6 2.3 0.5 10.9 2.3 2.0 1 0 0 1 1 1 0 SlyX Laminin_II PF06009.10 001293050.1_22223001_1 - 0.18 11.7 3.6 1.2 9.0 1.0 2.7 3 0 0 3 3 3 0 Laminin Domain II DivIC PF04977.13 001293050.1_22223001_1 - 0.25 11.0 3.0 0.6 9.8 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator MscS_porin PF12795.5 001293050.1_22223001_1 - 6.8 6.0 12.7 11 5.3 12.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Orn_Arg_deC_N PF02784.14 001293752.1_22223001_2 - 1.2e-62 211.4 0.0 1.5e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293752.1_22223001_2 - 1.5e-14 53.9 0.0 2.4e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001293752.1_22223001_2 - 0.044 13.1 0.0 0.093 12.0 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Acetyltransf_1 PF00583.23 073061.1_49923120_3 - 1.8e-14 53.8 0.0 3.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.5 073061.1_49923120_3 - 2.2e-06 27.9 0.0 5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.5 073061.1_49923120_3 - 0.00062 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.8 073061.1_49923120_3 - 0.0033 17.2 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein 7tm_1 PF00001.19 001316881.1_27823001_1 - 4.4e-51 173.5 21.8 6.2e-51 173.1 21.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_transf_29 PF00777.16 001316886.1_27823001_1 - 1.4e-80 270.5 0.1 1.6e-80 270.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.19 001316886.1_27823001_1 - 0.00019 20.2 0.0 0.00025 19.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glyco_transf_29 PF00777.16 001309394.1_27822001_1 - 1.6e-63 214.5 0.0 2.2e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Orn_Arg_deC_N PF02784.14 001294167.1_01524001_2 - 6.5e-73 245.1 0.0 7.9e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001294167.1_01524001_2 - 1.7e-27 95.6 0.0 2.9e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.22 001294167.1_01524001_2 - 0.0035 16.7 0.0 0.0079 15.5 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.14 001291725.1_01525001_1 - 5e-60 202.9 0.0 6.3e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291725.1_01525001_1 - 8.4e-22 77.2 0.0 1.7e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain TIR PF01582.18 001286912.1_41123001_2 - 1.5e-12 47.5 0.2 3.1e-12 46.5 0.2 1.5 2 0 0 2 2 2 1 TIR domain Death PF00531.20 001286912.1_41123001_2 - 2.3e-12 46.8 0.0 6.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Death domain TIR_2 PF13676.4 001286912.1_41123001_2 - 2.2e-11 43.8 0.0 3.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 TIR domain HMG_box_2 PF09011.8 001286910.1_41122001_3 - 3.1e-49 165.3 9.2 4.5e-30 103.9 6.2 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.17 001286910.1_41122001_3 - 2e-45 152.9 8.7 1.2e-27 95.9 0.1 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.4 001286910.1_41122001_3 - 0.00075 19.3 9.6 0.11 12.3 0.8 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Ribosomal_60s PF00428.17 001286910.1_41122001_3 - 0.094 13.1 18.7 0.24 11.8 18.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein YABBY PF04690.11 001286910.1_41122001_3 - 0.27 11.6 4.2 0.8 10.1 0.1 2.5 1 1 2 3 3 3 0 YABBY protein AAA PF00004.27 001293082.1_01524001_2 - 1.1e-42 145.5 0.0 2.4e-42 144.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293082.1_01524001_2 - 4.9e-07 29.9 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293082.1_01524001_2 - 6.8e-06 26.0 0.0 2.8e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293082.1_01524001_2 - 1.1e-05 25.8 0.1 0.00012 22.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.4 001293082.1_01524001_2 - 8e-05 22.8 0.8 0.017 15.3 0.0 2.6 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.10 001293082.1_01524001_2 - 0.00018 20.7 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293082.1_01524001_2 - 0.0028 16.5 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293082.1_01524001_2 - 0.0032 17.1 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293082.1_01524001_2 - 0.0033 17.5 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293082.1_01524001_2 - 0.0066 16.8 0.1 0.033 14.6 0.0 2.2 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.19 001293082.1_01524001_2 - 0.012 14.9 0.1 0.025 13.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.9 001293082.1_01524001_2 - 0.012 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.11 001293082.1_01524001_2 - 0.017 14.4 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.14 001293082.1_01524001_2 - 0.022 14.1 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.4 001293082.1_01524001_2 - 0.034 14.2 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293082.1_01524001_2 - 0.035 14.2 3.4 0.081 13.0 3.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293082.1_01524001_2 - 0.05 13.2 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293082.1_01524001_2 - 0.054 13.1 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.15 001293082.1_01524001_2 - 0.073 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293082.1_01524001_2 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.4 001293082.1_01524001_2 - 0.1 12.0 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.11 001293082.1_01524001_2 - 0.1 11.6 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.20 001293082.1_01524001_2 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.4 001293082.1_01524001_2 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.4 001293082.1_01524001_2 - 0.12 12.0 0.3 0.66 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain SlyX PF04102.10 001293082.1_01524001_2 - 0.39 11.2 2.6 1.1 9.8 2.6 1.7 1 0 0 1 1 1 0 SlyX Laminin_II PF06009.10 001293082.1_01524001_2 - 0.9 9.4 4.1 2 8.3 1.0 2.5 3 0 0 3 3 2 0 Laminin Domain II FOXP-CC PF16159.3 001316882.1_27825001_1 - 3.2e-35 120.4 4.2 3.2e-35 120.4 4.2 4.6 3 1 0 3 3 3 1 FOXP coiled-coil domain Forkhead PF00250.16 001316882.1_27825001_1 - 2.7e-28 98.0 0.2 1e-27 96.1 0.2 2.0 1 0 0 1 1 1 1 Forkhead domain Plasmodium_Vir PF05795.9 001316882.1_27825001_1 - 1.4 8.1 9.4 1.8 7.8 6.9 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TT_ORF1 PF02956.12 001316882.1_27825001_1 - 1.9 7.0 20.3 2.9 6.3 20.3 1.2 1 0 0 1 1 1 0 TT viral orf 1 Peptidase_S49_N PF08496.8 001316882.1_27825001_1 - 3.9 7.4 22.1 11 5.9 22.1 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2347 PF09804.7 001316882.1_27825001_1 - 4.2 6.7 12.9 8.4 5.8 12.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) hDGE_amylase PF14701.4 001316882.1_27825001_1 - 5.4 5.8 17.2 12 4.7 17.2 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain RR_TM4-6 PF06459.10 001316882.1_27825001_1 - 5.4 6.6 18.0 13 5.4 18.0 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_29 PF00777.16 001316883.1_27823001_1 - 2.1e-85 286.2 0.0 2.6e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.19 001316883.1_27823001_1 - 0.0029 16.3 0.0 0.0041 15.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glyco_transf_29 PF00777.16 001316884.1_27823001_1 - 8e-84 281.1 0.1 1e-83 280.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.19 001316884.1_27823001_1 - 0.0028 16.4 0.0 0.0037 16.0 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glyco_transf_29 PF00777.16 001316879.1_27822001_1 - 8.7e-78 261.3 0.2 1.1e-77 260.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Glyco_hydro_18 PF00704.26 001316885.1_27824001_2 - 5.6e-92 308.7 0.5 6.7e-92 308.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.22 001316885.1_27824001_2 - 9.5e-10 38.4 6.4 2e-09 37.3 6.4 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain SAA PF00277.16 001286929.1_41122001_2 - 1.7e-49 166.4 8.3 2.1e-49 166.1 8.3 1.1 1 0 0 1 1 1 1 Serum amyloid A protein Basic PF01586.14 001286906.1_41122001_1 - 1.6e-22 80.4 0.5 1.6e-22 80.4 0.5 2.2 3 0 0 3 3 3 1 Myogenic Basic domain Myf5 PF12232.6 001286906.1_41122001_1 - 4.9e-22 78.3 8.2 4.9e-22 78.3 8.2 2.1 2 0 0 2 2 2 1 Myogenic determination factor 5 HLH PF00010.24 001286906.1_41122001_1 - 1.2e-15 57.1 2.7 9.5e-15 54.2 4.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain GTP_EFTU PF00009.25 001286922.1_41124001_2 - 1.3e-54 184.6 0.0 1.8e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001286922.1_41124001_2 - 1e-39 135.2 0.0 2.1e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001286922.1_41124001_2 - 1.3e-14 54.2 2.1 1.4e-14 54.1 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001286922.1_41124001_2 - 0.00047 20.1 0.2 0.01 15.8 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001286922.1_41124001_2 - 0.011 15.6 1.6 0.019 14.8 0.3 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.21 001286922.1_41124001_2 - 0.13 12.2 0.1 20 5.0 0.1 2.4 2 0 0 2 2 2 0 Dynamin family ACTH_domain PF00976.16 001286918.1_41123001_1 - 2.1e-25 88.0 28.2 2.2e-09 36.9 5.2 3.6 3 0 0 3 3 3 3 Corticotropin ACTH domain NPP PF08384.8 001286918.1_41123001_1 - 2.3e-23 81.8 1.5 4.4e-23 80.9 1.5 1.5 1 0 0 1 1 1 1 Pro-opiomelanocortin, N-terminal region Op_neuropeptide PF08035.9 001286918.1_41123001_1 - 9e-16 57.3 0.2 1.6e-15 56.5 0.2 1.4 1 0 0 1 1 1 1 Opioids neuropeptide Tetraspannin PF00335.18 001286914.1_41123001_2 - 4e-43 147.6 12.3 5.5e-43 147.1 12.3 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1218 PF06749.10 001286914.1_41123001_2 - 0.79 10.1 10.3 0.68 10.4 2.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) DUF4870 PF09685.8 001286914.1_41123001_2 - 8 6.5 11.2 10 6.1 5.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Ig_J_chain PF15097.4 001286896.1_41125001_1 - 8.9e-66 219.7 8.0 1.3e-65 219.1 8.0 1.2 1 0 0 1 1 1 1 Immunoglobulin J chain Catalase PF00199.17 001286934.1_41125001_1 - 1.5e-195 649.5 0.0 2e-195 649.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.10 001286934.1_41125001_1 - 4.5e-16 58.7 0.5 1.5e-15 57.0 0.1 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive Orn_Arg_deC_N PF02784.14 001291741.1_41126001_3 - 1.9e-61 207.5 0.0 2.4e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291741.1_41126001_3 - 3.1e-22 78.6 0.0 5.8e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain TCR_zetazeta PF11628.6 001286921.1_41123001_3 - 1.5e-17 62.8 1.6 2.8e-17 62.0 1.6 1.5 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 zeta chain ITAM PF02189.13 001286921.1_41123001_3 - 2.6e-10 40.0 4.2 2.2e-05 24.5 0.1 3.5 3 0 0 3 3 3 3 Immunoreceptor tyrosine-based activation motif MHC_I_3 PF16497.3 001317039.1_01523001_1 - 6e-27 94.3 0.0 7.7e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.13 001317039.1_01523001_1 - 1.4e-15 57.3 0.0 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001317039.1_01523001_1 - 5.6e-11 42.2 0.0 7.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_3 PF13927.4 001317039.1_01523001_1 - 0.0022 18.4 0.0 0.0046 17.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ATP-synt_I PF03899.13 001317039.1_01523001_1 - 0.023 14.9 1.2 0.062 13.5 1.2 1.6 1 0 0 1 1 1 0 ATP synthase I chain I-set PF07679.14 001317039.1_01523001_1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.4 001317039.1_01523001_1 - 0.16 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Glyco_transf_29 PF00777.16 001317053.1_41123001_1 - 4.5e-58 196.6 0.1 5.6e-58 196.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Calc_CGRP_IAPP PF00214.17 001292180.1_08123001_2 - 8.1e-20 71.3 0.5 1.4e-19 70.5 0.5 1.4 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family 7tm_1 PF00001.19 001292206.1_08123001_3 - 9.1e-47 159.4 16.9 1.2e-46 159.0 16.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001292206.1_08123001_3 - 5.4e-06 25.8 12.5 6e-06 25.7 11.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001292206.1_08123001_3 - 2.1e-05 24.3 5.4 2.1e-05 24.3 5.4 2.1 3 0 0 3 3 3 1 Olfactory receptor DUF997 PF06196.10 001292206.1_08123001_3 - 1.3 8.9 10.7 2.9 7.8 1.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF997) CHD5 PF04420.12 001292322.1_08124001_3 - 8.2e-32 110.1 0.3 1.3e-31 109.5 0.3 1.2 1 0 0 1 1 1 1 CHD5-like protein EF-hand_1 PF00036.30 001292457.1_08122001_2 - 3.9e-16 57.2 7.1 2.4e-07 29.7 1.6 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.4 001292457.1_08122001_2 - 1.4e-15 57.3 5.3 1.9e-07 31.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001292457.1_08122001_2 - 1.2e-12 46.5 7.0 1.5e-07 30.6 0.9 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.4 001292457.1_08122001_2 - 6.7e-10 38.5 6.0 0.00046 19.8 0.1 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.4 001292457.1_08122001_2 - 1.2e-06 27.6 1.7 3.3e-05 23.1 1.5 2.7 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.8 001292457.1_08122001_2 - 0.00019 21.3 0.8 0.21 11.6 0.1 2.4 2 0 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_9 PF14658.4 001292457.1_08122001_2 - 0.0022 18.2 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.11 001292457.1_08122001_2 - 0.0047 16.8 0.0 3 7.8 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.9 001292457.1_08122001_2 - 0.014 16.1 0.3 0.047 14.4 0.1 1.8 1 1 1 2 2 2 0 EF-hand domain GPHH PF16905.3 001292457.1_08122001_2 - 0.032 13.9 0.1 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated SPARC_Ca_bdg PF10591.7 001292457.1_08122001_2 - 0.034 14.3 2.3 0.2 11.8 0.4 2.1 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_2 PF13623.4 001292457.1_08122001_2 - 0.047 13.4 0.3 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain DEAD PF00270.27 001292647.1_08125001_2 - 6.7e-43 146.4 0.1 1e-42 145.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001292647.1_08125001_2 - 2.9e-31 108.0 0.4 3.4e-30 104.5 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.13 001292647.1_08125001_2 - 8.4e-07 29.0 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.4 001292647.1_08125001_2 - 0.0036 17.5 0.2 0.0087 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.4 001292647.1_08125001_2 - 0.0059 16.2 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.12 001292647.1_08125001_2 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Helicase adh_short PF00106.23 001292800.1_08123001_2 - 2.8e-51 173.6 0.5 3.7e-51 173.2 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001292800.1_08123001_2 - 9.1e-40 136.5 0.3 1.2e-39 136.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001292800.1_08123001_2 - 3.3e-07 30.3 0.2 4.8e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001292800.1_08123001_2 - 0.00093 18.6 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001292800.1_08123001_2 - 0.0018 17.6 0.1 0.0066 15.7 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase LBP_BPI_CETP_C PF02886.15 001292820.1_08124001_3 - 7.6e-61 205.5 0.6 1.3e-60 204.7 0.6 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.23 001292820.1_08124001_3 - 2.8e-39 134.2 0.0 5.2e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Spuma_A9PTase PF03539.12 001292820.1_08124001_3 - 0.089 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Peptidase_M16 PF00675.18 001293025.1_08124001_1 - 1.3e-27 96.4 0.0 2.2e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001293025.1_08124001_1 - 1.1e-17 64.5 0.0 2.4e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain NTPase_1 PF03266.13 001293032.1_08122001_2 - 5.6e-61 205.2 0.1 6.6e-61 205.0 0.1 1.0 1 0 0 1 1 1 1 NTPase AAA_30 PF13604.4 001293032.1_08122001_2 - 3.2e-05 23.6 0.0 7.3e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.4 001293032.1_08122001_2 - 3.7e-05 23.9 0.1 0.0006 20.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.4 001293032.1_08122001_2 - 6.6e-05 23.2 0.1 0.00011 22.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.27 001293032.1_08122001_2 - 0.00033 21.0 0.1 0.00088 19.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.4 001293032.1_08122001_2 - 0.00042 20.5 0.2 0.00084 19.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.10 001293032.1_08122001_2 - 0.0019 17.4 0.1 0.0033 16.6 0.1 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.4 001293032.1_08122001_2 - 0.0021 18.4 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.4 001293032.1_08122001_2 - 0.0029 17.2 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.20 001293032.1_08122001_2 - 0.0029 17.8 0.3 0.01 16.1 0.0 2.0 3 0 0 3 3 2 1 RNA helicase AAA_14 PF13173.4 001293032.1_08122001_2 - 0.0041 17.0 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.10 001293032.1_08122001_2 - 0.0044 16.8 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.12 001293032.1_08122001_2 - 0.0064 16.4 0.1 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SRPRB PF09439.8 001293032.1_08122001_2 - 0.0074 15.6 0.0 0.5 9.6 0.0 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.17 001293032.1_08122001_2 - 0.02 14.3 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.14 001293032.1_08122001_2 - 0.021 13.7 0.1 0.041 12.7 0.1 1.4 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.4 001293032.1_08122001_2 - 0.022 14.8 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.19 001293032.1_08122001_2 - 0.023 13.9 0.2 0.038 13.2 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.16 001293032.1_08122001_2 - 0.023 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.4 001293032.1_08122001_2 - 0.028 14.0 0.1 0.064 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.4 001293032.1_08122001_2 - 0.039 14.1 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.7 001293032.1_08122001_2 - 0.042 12.6 0.2 0.062 12.1 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.21 001293032.1_08122001_2 - 0.045 13.7 0.1 0.077 13.0 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.12 001293032.1_08122001_2 - 0.048 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.15 001293032.1_08122001_2 - 0.056 13.1 0.1 0.13 11.9 0.0 1.6 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein DUF258 PF03193.14 001293032.1_08122001_2 - 0.06 13.1 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TsaE PF02367.15 001293032.1_08122001_2 - 0.09 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.4 001293032.1_08122001_2 - 0.097 12.1 0.3 0.22 10.9 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.4 001293032.1_08122001_2 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.20 001293032.1_08122001_2 - 0.13 11.1 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.11 001293032.1_08122001_2 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.7 001293032.1_08122001_2 - 0.16 11.0 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 7tm_1 PF00001.19 001293131.1_02223001_1 - 3.2e-39 134.7 14.8 4.4e-39 134.2 14.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001293131.1_02223001_1 - 1e-06 28.2 10.1 1e-06 28.2 10.1 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.11 001293131.1_02223001_1 - 0.00012 21.1 1.3 0.00012 21.1 1.3 2.4 3 0 0 3 3 3 1 Taste receptor protein (TAS2R) 7tm_4 PF13853.4 001293131.1_02223001_1 - 0.013 15.1 14.5 0.15 11.7 14.5 2.0 1 1 0 1 1 1 0 Olfactory receptor DUF1201 PF06716.9 001293131.1_02223001_1 - 3.9 7.4 7.3 8 6.4 2.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) BNR_2 PF13088.4 001293247.1_02223001_1 - 6.8e-40 137.0 0.0 9e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.4 001293247.1_02223001_1 - 8.2e-10 38.3 0.0 1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.18 001293247.1_02223001_1 - 0.02 14.7 14.8 0.03 14.1 0.5 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat Sortilin-Vps10 PF15902.3 001293247.1_02223001_1 - 0.13 10.9 0.1 3.1 6.4 0.0 2.0 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.11 001293247.1_02223001_1 - 0.14 12.0 0.2 28 4.7 0.0 2.9 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF4185 PF13810.4 001293247.1_02223001_1 - 0.21 10.7 0.3 3 6.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4185) Ald_Xan_dh_C2 PF02738.16 001293248.1_02229001_1 - 1.2e-193 644.4 0.0 1.5e-193 644.1 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001293248.1_02229001_1 - 4.1e-43 146.9 0.0 9.8e-43 145.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001293248.1_02229001_1 - 9.5e-34 115.9 3.0 2e-33 114.9 3.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001293248.1_02229001_1 - 3.9e-32 110.4 0.0 1.7e-31 108.3 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.18 001293248.1_02229001_1 - 9.5e-31 105.5 0.1 2.8e-30 103.9 0.1 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.25 001293248.1_02229001_1 - 1.2e-08 34.7 3.1 1.2e-08 34.7 0.1 2.7 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain 7tm_1 PF00001.19 001294182.1_49225001_2 - 4.2e-48 163.8 18.5 6.4e-48 163.2 18.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001294182.1_49225001_2 - 3.2e-06 26.9 5.2 6e-06 26.1 5.2 1.4 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001294184.1_49224001_2 - 3.8e-47 160.6 19.2 5.1e-47 160.2 19.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001294184.1_49224001_2 - 1.1e-08 34.6 18.3 1.7e-08 34.0 18.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001294184.1_49224001_2 - 4.9e-06 26.4 5.3 8.9e-06 25.5 5.3 1.4 1 0 0 1 1 1 1 Olfactory receptor DUF5134 PF17197.2 001294184.1_49224001_2 - 0.58 9.9 3.6 0.48 10.2 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) MIP PF00230.18 001294192.1_15723001_1 - 7.6e-69 231.7 8.0 9.5e-69 231.4 8.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Transferrin PF00405.15 001294244.1_15725001_3 - 2.1e-196 651.5 9.8 1.5e-107 359.5 0.7 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.5 001294244.1_15725001_3 - 3.4e-05 23.4 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein Ank_2 PF12796.5 001297585.1_15722001_1 - 3.8e-24 85.0 5.7 4e-14 52.8 0.7 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.28 001297585.1_15722001_1 - 5e-21 74.0 14.8 0.00048 20.3 0.2 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.4 001297585.1_15722001_1 - 5.5e-21 72.3 7.6 0.00025 21.1 0.1 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.4 001297585.1_15722001_1 - 4e-20 71.8 8.7 2.2e-05 24.8 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.4 001297585.1_15722001_1 - 7.9e-20 70.5 7.4 8.2e-08 32.3 0.1 4.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) ubiquitin PF00240.21 001301006.1_15723001_1 - 7.3e-26 89.6 0.5 6.2e-14 51.4 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.6 001301006.1_15723001_1 - 1.1e-09 37.9 0.5 4.4e-05 23.1 0.2 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001301006.1_15723001_1 - 1.4e-07 31.7 0.4 0.01 16.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-like domain UN_NPL4 PF11543.6 001301006.1_15723001_1 - 5.2e-06 26.7 0.4 0.011 16.0 0.0 2.4 2 0 0 2 2 2 2 Nuclear pore localisation protein NPL4 USP7_C2 PF14533.4 001301006.1_15723001_1 - 0.0011 18.6 0.1 0.083 12.5 0.0 2.2 1 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal bZIP_2 PF07716.13 001172496.1_36923001_2 - 2.2e-15 56.3 11.3 2.2e-15 56.3 11.3 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.19 001172496.1_36923001_2 - 8.3e-05 22.5 5.8 0.00017 21.5 5.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Lipoprotein_20 PF13942.4 001172496.1_36923001_2 - 0.014 15.3 1.1 0.024 14.4 1.1 1.3 1 0 0 1 1 1 0 YfhG lipoprotein Nup54 PF13874.4 001172496.1_36923001_2 - 0.014 15.4 0.9 0.014 15.4 0.9 1.7 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 bZIP_Maf PF03131.15 001172496.1_36923001_2 - 0.03 14.7 4.4 0.03 14.7 4.4 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF2514 PF10721.7 001172496.1_36923001_2 - 0.059 13.3 3.5 0.42 10.5 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Orn_Arg_deC_N PF02784.14 001301788.1_12026001_2 - 5.2e-66 222.4 0.0 6.5e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301788.1_12026001_2 - 3.1e-23 81.8 0.0 5.3e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291606.1_12026001_2 - 4.9e-66 222.5 0.0 6.1e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291606.1_12026001_2 - 2.9e-23 81.9 0.0 5.1e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Globin PF00042.20 001302160.1_03322001_1 - 3.6e-21 75.7 0.1 6.1e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Globin Lipocalin PF00061.21 001303662.1_21522001_3 - 1.4e-23 83.6 2.3 1.9e-23 83.1 2.3 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001303662.1_21522001_3 - 0.0011 18.8 1.2 0.0016 18.2 1.2 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Myotoxins PF00819.15 001303737.1_21523001_1 - 0.031 14.4 0.2 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 Myotoxin, crotamine TMEM18 PF14770.4 001303737.1_21523001_3 - 8.2e-45 151.4 11.4 1.3e-44 150.8 11.4 1.3 1 0 0 1 1 1 1 Transmembrane protein 18 DUF4752 PF15944.3 001303737.1_21523001_3 - 0.34 10.9 0.1 0.34 10.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4752) MRP-L47 PF06984.11 001303992.1_21522001_1 - 8e-32 109.1 0.5 1.7e-31 108.1 0.5 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.21 001303992.1_21522001_1 - 0.0002 21.2 3.7 0.00051 19.8 3.7 1.8 1 0 0 1 1 1 1 Ribosomal L29 protein Rotamase_3 PF13616.4 001304012.1_21522001_2 - 3.2e-19 69.5 0.1 1e-18 67.8 0.1 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.19 001304012.1_21522001_2 - 2.7e-15 57.0 0.0 5.1e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.4 001304012.1_21522001_2 - 0.041 14.6 0.0 0.061 14.1 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain GDP_Man_Dehyd PF16363.3 001304225.1_21523001_1 - 3.5e-54 184.3 0.0 4.1e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.19 001304225.1_21523001_1 - 4e-50 170.4 0.0 5e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001304225.1_21523001_1 - 1.1e-16 60.6 0.0 2.2e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.13 001304225.1_21523001_1 - 1.4e-11 44.0 0.0 9.1e-11 41.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001304225.1_21523001_1 - 4.1e-11 42.4 0.0 6.4e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.10 001304225.1_21523001_1 - 1.4e-06 27.5 0.0 1.8e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.8 001304225.1_21523001_1 - 9.8e-05 22.2 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.4 001304225.1_21523001_1 - 0.0001 22.1 0.0 0.00026 20.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.23 001304225.1_21523001_1 - 0.0046 16.3 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.11 001304225.1_21523001_1 - 0.019 14.4 0.3 5.8 6.3 0.0 2.6 2 1 0 2 2 2 0 NmrA-like family Orn_Arg_deC_N PF02784.14 001308125.1_42727001_3 - 1.3e-57 194.9 0.0 1.7e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001308125.1_42727001_3 - 5e-12 45.8 0.0 9.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Palm_thioest PF02089.13 001310905.1_21523001_3 - 2.9e-139 462.9 0.0 3.4e-139 462.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Ocnus PF05005.13 001310944.1_21521001_3 - 2.8e-34 117.3 0.1 3.7e-34 116.9 0.1 1.1 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) UQ_con PF00179.24 001310989.1_21523001_1 - 1.9e-53 179.7 0.0 2.7e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001310989.1_21523001_1 - 0.0017 18.5 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.4 001310989.1_21523001_1 - 0.019 14.5 0.6 0.035 13.7 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic E2 family B MIP PF00230.18 001311333.1_37523001_3 - 2.6e-47 161.3 10.3 3.6e-47 160.8 10.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Thioredoxin PF00085.18 001281547.1_30923001_2 - 1.1e-27 95.9 0.1 1.5e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.4 001281547.1_30923001_2 - 3.7e-07 30.4 0.1 3.1e-06 27.5 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.4 001281547.1_30923001_2 - 8e-05 22.6 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.4 001281547.1_30923001_2 - 0.0012 18.7 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.4 001281547.1_30923001_2 - 0.0064 16.7 0.0 0.19 12.0 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.19 001281547.1_30923001_2 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.4 001281547.1_30923001_2 - 0.056 13.1 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.18 001281547.1_30923001_2 - 0.12 11.9 0.1 1.2 8.7 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain RNase_H PF00075.22 001286010.1_02223001_3 - 2.5e-44 150.8 0.1 4.6e-44 150.0 0.1 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001286010.1_02223001_3 - 7.8e-19 67.6 3.9 1.8e-18 66.5 3.9 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001286010.1_02223001_3 - 0.0011 18.5 0.0 0.0069 16.0 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase-like COesterase PF00135.26 001291388.1_02225001_1 - 3.8e-194 646.3 0.0 4.5e-194 646.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001291388.1_02225001_1 - 2.6e-07 30.6 0.2 1.6e-06 28.0 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001291388.1_02225001_1 - 0.013 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Orn_Arg_deC_N PF02784.14 001291596.1_30925001_3 - 1e-62 211.7 0.0 1.2e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291596.1_30925001_3 - 3e-22 78.7 0.0 8.3e-22 77.2 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291648.1_24025001_3 - 3.9e-64 216.3 0.0 5e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291648.1_24025001_3 - 1.3e-22 79.9 0.0 2.7e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291775.1_11125001_1 - 8.7e-67 225.0 0.2 1.7e-66 224.1 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291775.1_11125001_1 - 4e-24 84.7 0.0 7.6e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DM PF00751.16 001309024.1_39123001_3 - 5.9e-21 74.0 11.7 1.3e-20 72.9 11.7 1.6 1 0 0 1 1 1 1 DM DNA binding domain Dmrt1 PF12374.6 001309024.1_39123001_3 - 1.9e-19 69.7 2.9 4.4e-19 68.5 2.9 1.7 1 0 0 1 1 1 1 Double-sex mab3 related transcription factor 1 MAGE_N PF12440.6 001309024.1_39123001_3 - 0.11 13.0 1.4 0.28 11.8 1.4 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal MHC_II_beta PF00969.17 001310784.1_02123001_1 - 7.1e-31 106.0 0.4 1.1e-30 105.4 0.4 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001310784.1_02123001_1 - 4.5e-25 87.8 0.5 6.6e-25 87.3 0.5 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001310784.1_02123001_1 - 1.4e-05 25.4 0.2 2.2e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001310784.1_02123001_1 - 0.002 18.0 0.1 0.0033 17.3 0.1 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 001310784.1_02123001_1 - 0.0069 16.6 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001310784.1_02123001_1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.23 001310784.1_02123001_1 - 0.093 12.8 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Immunoglobulin domain zf-H2C2_2 PF13465.4 001317046.1_41125001_1 - 2.6e-14 52.8 7.4 1.2e-08 34.9 1.1 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.24 001317046.1_41125001_1 - 1.7e-13 50.1 26.8 2.4e-06 27.6 0.8 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001317046.1_41125001_1 - 3.6e-06 27.2 8.7 0.00026 21.4 1.6 4.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.10 001317046.1_41125001_1 - 0.00081 19.5 2.0 0.00081 19.5 2.0 2.5 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.5 001317046.1_41125001_1 - 0.0024 18.1 8.0 0.078 13.3 0.8 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001317046.1_41125001_1 - 0.0032 17.6 3.7 1.3 9.3 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001317046.1_41125001_1 - 0.0094 15.8 14.6 0.013 15.3 1.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001317046.1_41125001_1 - 0.022 14.9 4.2 0.061 13.5 4.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_9 PF16293.3 001317046.1_41125001_1 - 1.6 8.5 4.6 0.28 10.9 0.2 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) IRF PF00605.15 001317050.1_41122001_1 - 1.8e-40 137.3 0.5 4.5e-40 136.0 0.5 1.7 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Glyco_transf_29 PF00777.16 001318912.1_28122001_1 - 2.1e-79 266.6 0.1 2.6e-79 266.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF5051 PF16473.3 001318912.1_28122001_1 - 0.017 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like DUF1453 PF07301.9 001318912.1_28122001_1 - 0.065 13.1 0.5 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) Glyco_transf_29 PF00777.16 001318910.1_28123001_1 - 7.6e-67 225.4 0.0 9.9e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Laminin_G_2 PF02210.22 001319130.1_14729001_1 - 5.4e-149 489.0 10.8 3.4e-28 98.6 0.0 6.3 6 0 0 6 6 6 6 Laminin G domain Laminin_G_1 PF00054.21 001319130.1_14729001_1 - 2.9e-106 350.9 5.7 5.3e-25 88.0 0.0 7.7 7 1 0 7 7 7 6 Laminin G domain Laminin_G_3 PF13385.4 001319130.1_14729001_1 - 9.8e-22 77.6 5.5 0.0001 22.4 0.2 6.5 6 0 0 6 6 6 6 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.25 001319130.1_14729001_1 - 7.4e-14 51.6 35.5 1.9e-06 27.9 7.5 3.6 3 0 0 3 3 3 3 EGF-like domain Syndecan PF01034.18 001319130.1_14729001_1 - 2.7e-07 30.3 0.0 5.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain hEGF PF12661.5 001319130.1_14729001_1 - 4.5e-05 23.8 25.7 0.29 11.7 2.8 4.2 3 0 0 3 3 3 3 Human growth factor-like EGF DUF1080 PF06439.9 001319130.1_14729001_1 - 7.6e-05 22.8 2.5 2.9 7.8 0.0 4.4 4 0 0 4 4 4 2 Domain of Unknown Function (DUF1080) DUF202 PF02656.13 001319130.1_14729001_1 - 0.089 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) p450 PF00067.20 001302364.1_41624001_3 - 3.3e-125 418.3 0.1 4.5e-125 417.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4750 PF15938.3 001302364.1_41624001_3 - 0.14 11.7 2.3 0.56 9.8 2.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) Cid2 PF09774.7 102734.1_23522120_1 - 4.1e-15 56.4 10.1 1.8e-10 41.3 2.7 2.2 2 0 0 2 2 2 2 Caffeine-induced death protein 2 Herpes_BTRF1 PF04682.10 102734.1_23522120_1 - 0.055 12.7 0.1 0.081 12.1 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region FUN14 PF04930.13 075082.1_23526120_1 - 2.1e-10 40.7 0.1 3.2e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 FUN14 family Prefoldin_2 PF01920.18 102331.1_23522120_2 - 6.5e-15 54.9 4.5 9.6e-15 54.3 4.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit COMM_domain PF07258.12 102412.2_23522120_2 - 2.2e-16 59.6 0.0 4.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 COMM domain Troponin-I_N PF11636.6 102412.2_23522120_3 - 0.00081 19.1 1.2 0.00081 19.1 1.2 3.2 3 0 0 3 3 3 1 Troponin I residues 1-32 Glyco_transf_29 PF00777.16 001321139.1_45423001_1 - 5.6e-71 238.9 0.0 8.5e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.19 001321139.1_45423001_1 - 0.076 11.6 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Glyco_transf_29 PF00777.16 001321138.1_45422001_1 - 3.6e-77 259.2 0.0 4.1e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Glyco_transf_29 PF00777.16 001321141.1_45423001_1 - 2.8e-65 220.3 0.0 3.5e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Glyco_transf_29 PF00777.16 001321140.1_45423001_1 - 6.7e-69 232.1 0.0 7.8e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) WD40 PF00400.30 033391.1_53524120_1 - 1.3e-18 66.8 5.7 0.00013 22.5 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 033391.1_53524120_1 - 0.00011 22.2 0.0 3 8.1 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CDT1 PF08839.9 001323186.1_13925001_1 - 1.5e-62 210.9 0.4 4.9e-62 209.2 0.4 1.8 2 0 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.3 001323186.1_13925001_1 - 4e-29 100.7 0.6 1e-27 96.2 0.5 3.0 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain fn3 PF00041.19 001323190.1_13929001_1 - 5.7e-263 850.1 74.8 4.8e-20 71.6 0.4 17.3 17 0 0 17 17 17 17 Fibronectin type III domain fn1 PF00039.16 001323190.1_13929001_1 - 3.8e-148 481.3 168.1 4.5e-15 55.4 5.2 12.7 12 0 0 12 12 12 12 Fibronectin type I domain DUF2369 PF10179.7 001323190.1_13929001_1 - 1.6e-32 111.7 11.4 0.084 13.2 0.0 14.5 16 1 1 17 17 15 8 Uncharacterised conserved protein (DUF2369) fn2 PF00040.17 001323190.1_13929001_1 - 1.8e-31 108.0 29.5 1.1e-16 60.6 7.1 3.8 3 0 0 3 3 2 2 Fibronectin type II domain Pur_ac_phosph_N PF16656.3 001323190.1_13929001_1 - 2.3e-29 101.7 55.2 0.00034 21.0 0.0 20.1 16 8 1 17 17 17 8 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.8 001323190.1_13929001_1 - 1.7e-18 66.7 0.0 0.66 10.2 0.0 12.1 13 0 0 13 13 13 3 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.3 001323190.1_13929001_1 - 1.4e-09 38.1 5.3 1.9 8.7 0.0 8.8 9 0 0 9 9 9 2 Domain of unknown function (DUF4959) DUF4912 PF16258.3 001323190.1_13929001_1 - 2.2e-07 31.0 0.0 3.8 7.6 0.0 7.1 9 0 0 9 9 9 2 Domain of unknown function (DUF4912) DUF1410 PF07198.9 001323190.1_13929001_1 - 0.00026 21.4 3.9 16 6.0 0.0 6.9 9 0 0 9 9 8 0 Protein of unknown function (DUF1410) TILa PF12714.5 001323190.1_13929001_1 - 0.00085 19.1 1.2 0.00085 19.1 1.2 11.1 5 3 7 12 12 12 1 TILa domain fn3_2 PF16893.3 001323190.1_13929001_1 - 0.0098 15.9 9.4 0.7 9.9 0.0 7.3 7 1 0 7 7 7 1 Fibronectin type III domain Glyco_hydro_66 PF13199.4 001323190.1_13929001_1 - 0.012 14.1 3.9 33 2.8 0.0 5.8 5 2 2 7 7 7 0 Glycosyl hydrolase family 66 DUF2012 PF09430.8 001323190.1_13929001_1 - 0.027 14.5 0.2 25 4.9 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2012) 7tm_1 PF00001.19 001323192.1_13922001_1 - 6.8e-36 123.7 13.5 1.1e-35 123.0 13.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001323192.1_13922001_1 - 2.9e-06 27.1 6.3 5.4e-06 26.2 6.4 1.3 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001323192.1_13922001_1 - 0.006 15.8 14.5 0.0099 15.1 14.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Gaa1 PF04114.12 001323192.1_13922001_1 - 0.069 12.1 6.0 0.089 11.7 6.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component zf-LITAF-like PF10601.7 001323192.1_13922001_1 - 7.9 6.7 10.9 33 4.7 0.1 3.9 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain Peptidase_M28 PF04389.15 001323250.1_44123001_2 - 6e-46 156.5 0.0 7.6e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 7tm_1 PF00001.19 001323208.1_13923001_2 - 2.6e-33 115.3 12.9 3.7e-33 114.8 12.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001323208.1_13923001_2 - 0.00021 20.6 13.4 0.0018 17.6 13.4 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001323208.1_13923001_2 - 0.0067 15.6 8.1 0.01 15.0 7.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001323208.1_13923001_2 - 0.038 13.6 7.4 0.051 13.2 7.4 1.2 1 0 0 1 1 1 0 Olfactory receptor DUF2070 PF09843.7 001323208.1_13923001_2 - 1.5 6.8 4.0 0.38 8.9 0.3 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Zona_pellucida PF00100.21 001323213.1_13923001_1 - 1.2e-49 169.3 1.0 1.5e-49 168.9 1.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.25 001323213.1_13923001_1 - 8.5e-07 29.0 6.5 8.5e-07 29.0 6.5 2.0 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.5 001323213.1_13923001_1 - 0.0011 19.5 2.2 0.0011 19.5 2.2 2.0 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_2 PF07974.11 001323213.1_13923001_1 - 0.0011 19.1 7.1 0.0024 18.1 7.1 1.6 1 0 0 1 1 1 1 EGF-like domain cEGF PF12662.5 001323213.1_13923001_1 - 0.062 13.1 1.7 0.14 12.0 1.7 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_3 PF12947.5 001323213.1_13923001_1 - 0.39 10.8 5.5 0.82 9.8 5.5 1.6 1 0 0 1 1 1 0 EGF domain Pou PF00157.15 001323230.1_13923001_2 - 3e-38 129.5 0.2 4.6e-38 129.0 0.2 1.3 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001323230.1_13923001_2 - 1.4e-18 66.3 1.4 2.3e-18 65.6 0.3 1.8 2 0 0 2 2 2 1 Homeobox domain HTH_31 PF13560.4 001323230.1_13923001_2 - 0.0021 18.2 0.3 0.098 12.9 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain Homeobox_KN PF05920.9 001323230.1_13923001_2 - 0.01 15.6 0.1 0.038 13.8 0.0 1.9 2 0 0 2 2 2 0 Homeobox KN domain 7tm_2 PF00002.22 001323242.1_13925001_1 - 9.2e-92 306.6 23.4 1.4e-91 306.0 23.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.20 001323242.1_13925001_1 - 4e-21 74.9 3.4 4e-21 74.9 3.4 2.0 2 0 0 2 2 2 1 Hormone receptor domain DUF805 PF05656.12 001323242.1_13925001_1 - 5.6 7.3 10.4 0.85 9.9 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) 7tm_1 PF00001.19 001323223.1_13923001_1 - 1.7e-40 138.9 11.9 2.7e-40 138.2 11.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.7 001323223.1_13923001_1 - 0.15 11.2 11.0 0.61 9.2 11.0 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx YqzM PF14141.4 001323223.1_13923001_1 - 1.3 9.0 3.6 4.1 7.4 3.6 1.9 1 0 0 1 1 1 0 YqzM-like protein PAS_11 PF14598.4 001323217.1_13929001_1 - 2.5e-37 127.3 0.0 4e-33 113.8 0.0 2.4 2 0 0 2 2 2 2 PAS domain NCOA_u2 PF16665.3 001323217.1_13929001_1 - 1.5e-31 109.0 17.3 1.5e-31 109.0 17.3 5.6 6 1 0 6 6 3 1 Unstructured region on nuclear receptor coactivator protein DUF1518 PF07469.10 001323217.1_13929001_1 - 1.8e-30 105.0 41.4 1.9e-19 69.6 20.3 8.5 10 1 0 10 10 3 2 Domain of unknown function (DUF1518) SRC-1 PF08832.8 001323217.1_13929001_1 - 1.8e-22 80.1 4.6 1.8e-22 80.1 4.6 2.9 2 0 0 2 2 1 1 Steroid receptor coactivator Nuc_rec_co-act PF08815.8 001323217.1_13929001_1 - 2.6e-20 71.9 1.3 2.6e-20 71.9 1.3 2.5 2 0 0 2 2 2 1 Nuclear receptor coactivator PAS PF00989.23 001323217.1_13929001_1 - 1e-08 35.0 0.0 6.8e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.10 001323217.1_13929001_1 - 7.4e-08 32.4 0.0 0.00063 19.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.5 001323217.1_13929001_1 - 1.1e-06 28.7 0.0 5.1e-05 23.3 0.0 2.7 2 0 0 2 2 2 1 PAS domain DUF4927 PF16279.3 001323217.1_13929001_1 - 4.4e-06 27.5 5.4 4.4e-06 27.5 5.4 3.0 3 0 0 3 3 2 1 Domain of unknown function (DUF4927) HLH PF00010.24 001323217.1_13929001_1 - 9.5e-06 25.4 0.5 9.5e-06 25.4 0.5 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.8 001323217.1_13929001_1 - 0.026 14.6 0.0 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold CXCL17 PF15211.4 001323217.1_13929001_1 - 0.1 13.3 2.7 2.3 8.9 0.2 2.7 2 0 0 2 2 2 0 VEGF co-regulated chemokine 1 HMG_box PF00505.17 001323491.1_23923001_2 - 5.9e-43 145.0 10.1 6.8e-26 90.3 0.1 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.8 001323491.1_23923001_2 - 3.9e-42 142.6 11.0 1.6e-26 92.5 7.5 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.4 001323491.1_23923001_2 - 0.0051 16.6 10.2 0.4 10.6 2.9 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 5 DUF769 PF05590.9 001323491.1_23923001_2 - 0.014 14.7 0.4 0.022 14.1 0.4 1.4 1 1 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) DUF913 PF06025.10 001323491.1_23923001_2 - 0.034 13.0 0.5 0.054 12.3 0.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.10 001323491.1_23923001_2 - 0.42 9.8 20.3 0.76 9.0 20.3 1.4 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.10 001323491.1_23923001_2 - 3 7.0 17.0 4.4 6.5 17.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Noggin PF05806.10 001323493.1_23923001_1 - 1e-96 322.9 6.4 1.4e-96 322.4 6.4 1.2 1 0 0 1 1 1 1 Noggin PMSR PF01625.19 001323795.1_35922001_1 - 7.9e-66 220.8 2.5 9.9e-66 220.5 2.5 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PCNA_C PF02747.13 001323796.1_35923001_3 - 5e-61 204.4 0.1 7.7e-61 203.8 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.16 001323796.1_35923001_3 - 4.9e-58 194.2 3.1 9.8e-58 193.2 3.1 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.14 001323796.1_35923001_3 - 7.7e-10 38.2 0.6 1.8e-09 37.0 0.6 1.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.11 001323796.1_35923001_3 - 1.4e-05 24.6 0.2 1.9e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 Rad9 SIR2 PF02146.15 001323797.1_35925001_2 - 2.8e-64 216.1 0.0 4.3e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.11 001323797.1_35925001_2 - 0.0028 17.3 0.2 0.0051 16.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.20 001323797.1_35925001_2 - 0.0036 16.9 0.1 4 7.1 0.0 2.6 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain MRP-L47 PF06984.11 001323495.1_23922001_3 - 2.1e-35 120.6 1.1 3.4e-35 119.9 1.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) WT1 PF02165.13 001323793.1_35925001_2 - 1.3e-124 415.1 28.7 1.6e-97 326.2 22.8 2.2 1 1 1 2 2 2 2 Wilm's tumour protein zf-H2C2_2 PF13465.4 001323793.1_35925001_2 - 5.3e-15 55.0 26.8 1.5e-05 25.1 0.7 5.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.24 001323793.1_35925001_2 - 2.7e-07 30.6 21.8 9.7e-05 22.5 0.8 6.3 7 0 0 7 7 7 4 Zinc finger, C2H2 type FOXP-CC PF16159.3 001323793.1_35925001_2 - 0.0002 21.7 4.9 0.0063 17.0 0.4 3.2 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-met PF12874.5 001323793.1_35925001_2 - 0.00075 19.7 2.6 0.00075 19.7 2.6 5.7 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001323793.1_35925001_2 - 0.021 15.0 0.7 0.021 15.0 0.7 4.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.4 001323793.1_35925001_2 - 0.029 15.0 0.5 0.029 15.0 0.5 7.2 6 0 0 6 6 6 0 C2H2-type zinc finger P53 PF00870.16 001323800.1_35923001_1 - 5.7e-104 345.8 0.7 8.3e-104 345.2 0.7 1.2 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.9 001323800.1_35923001_1 - 4.8e-05 22.5 1.2 4.8e-05 22.5 1.2 2.0 2 0 0 2 2 2 1 P53 tetramerisation motif WT1 PF02165.13 001323791.1_35925001_1 - 4.7e-145 482.2 9.9 4.7e-145 482.2 9.9 2.2 2 0 0 2 2 2 1 Wilm's tumour protein zf-C2H2 PF00096.24 001323791.1_35925001_1 - 1.2e-15 56.8 35.8 2.2e-06 27.7 2.1 6.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001323791.1_35925001_1 - 9.3e-10 38.4 9.3 3.8e-06 27.0 1.5 6.1 6 1 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 001323791.1_35925001_1 - 9.2e-07 29.1 30.8 0.00092 19.7 1.3 6.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.5 001323791.1_35925001_1 - 0.003 17.8 2.0 0.003 17.8 2.0 5.2 5 1 0 5 5 5 2 Zinc-finger of C2H2 type FOXP-CC PF16159.3 001323791.1_35925001_1 - 0.016 15.7 0.3 0.016 15.7 0.3 4.1 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.6 001323791.1_35925001_1 - 0.019 15.2 8.8 0.14 12.4 0.3 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Neuromodulin PF06614.9 001323489.1_23924001_1 - 9.5e-52 175.5 61.2 9.5e-52 175.5 61.2 1.6 1 1 0 1 1 1 1 Neuromodulin Neuromodulin_N PF10580.7 001323489.1_23924001_1 - 1.5e-18 66.0 5.4 4e-18 64.7 5.4 1.8 1 0 0 1 1 1 1 Gap junction protein N-terminal region IQ PF00612.25 001323489.1_23924001_1 - 6.1e-06 25.4 0.4 6.1e-06 25.4 0.4 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif Connexin PF00029.17 001323789.1_35923001_1 - 2.4e-96 321.7 7.1 3e-96 321.4 7.1 1.1 1 0 0 1 1 1 1 Connexin Forkhead PF00250.16 001323961.1_44622001_1 - 2.9e-25 88.2 0.1 4e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 Forkhead domain FOXP-CC PF16159.3 001323961.1_44622001_1 - 0.007 16.8 1.4 0.012 16.0 1.4 1.3 1 0 0 1 1 1 1 FOXP coiled-coil domain CENP-Q PF13094.4 001323961.1_44622001_1 - 0.028 14.5 0.1 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Bcr-Abl_Oligo PF09036.8 001323961.1_44622001_1 - 0.051 13.4 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Telomerase_RBD PF12009.6 001323799.1_35927001_1 - 8.5e-33 113.2 0.1 2.7e-32 111.6 0.1 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.25 001323799.1_35927001_1 - 4.3e-15 55.7 0.0 6.6e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.15 001323792.1_35929001_2 - 3.6e-93 311.5 0.0 6e-93 310.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.22 001323792.1_35929001_2 - 4.1e-54 181.3 3.1 2.1e-27 95.3 0.2 2.6 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.23 001323792.1_35929001_2 - 2e-39 135.4 0.0 2.9e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.18 001323792.1_35929001_2 - 8.7e-39 132.6 39.3 1.8e-38 131.7 39.3 1.5 1 0 0 1 1 1 1 Furin-like cysteine rich region fn3 PF00041.19 001323792.1_35929001_2 - 7.3e-19 67.8 5.6 0.00047 20.3 0.2 4.7 4 0 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.4 001323792.1_35929001_2 - 0.03 13.5 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Y_Y_Y PF07495.11 001323792.1_35929001_2 - 0.1 12.4 0.5 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Y_Y_Y domain Ald_Xan_dh_C2 PF02738.16 001289422.1_28128001_1 - 7.9e-193 641.7 0.1 1.1e-192 641.2 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001289422.1_28128001_1 - 1.4e-43 148.4 0.0 4.2e-43 146.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001289422.1_28128001_1 - 3.1e-34 117.5 0.1 7.9e-34 116.2 0.1 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001289422.1_28128001_1 - 2.3e-31 107.5 0.1 5.7e-31 106.2 0.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001289422.1_28128001_1 - 4.1e-29 100.6 0.0 8.6e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001289422.1_28128001_1 - 3.7e-08 33.1 0.1 3.7e-08 33.1 0.1 2.8 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001289422.1_28128001_1 - 0.15 11.8 5.4 0.056 13.1 1.3 2.5 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Ald_Xan_dh_C2 PF02738.16 001289424.1_28129001_1 - 6.4e-192 638.7 0.0 8.5e-192 638.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001289424.1_28129001_1 - 1.9e-44 151.3 0.0 4.9e-44 149.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.18 001289424.1_28129001_1 - 5.1e-31 106.3 0.3 1.5e-30 104.8 0.2 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.20 001289424.1_28129001_1 - 1.3e-29 102.6 0.1 3.6e-28 98.0 0.1 2.6 1 1 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.15 001289424.1_28129001_1 - 1e-28 99.4 0.0 5.2e-28 97.1 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001289424.1_28129001_1 - 2.1e-09 37.0 0.2 2.1e-09 37.0 0.2 2.7 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r4 PF04545.14 001289424.1_28129001_1 - 0.034 13.5 0.1 0.19 11.2 0.0 2.3 3 0 0 3 3 3 0 Sigma-70, region 4 DHODB_Fe-S_bind PF10418.7 001289424.1_28129001_1 - 0.066 12.9 2.2 0.23 11.1 2.2 1.9 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Glyco_transf_29 PF00777.16 001318705.1_28123001_1 - 9.8e-83 277.5 0.0 1.1e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.19 001318705.1_28123001_1 - 0.046 12.4 0.0 0.065 11.9 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Orn_Arg_deC_N PF02784.14 001292031.1_04126001_1 - 2.6e-55 187.4 0.0 3.1e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001292031.1_04126001_1 - 1.8e-15 56.9 0.0 3.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain TPR_1 PF00515.26 001165315.1_46928001_3 - 1.4e-06 27.7 5.0 0.03 14.0 1.2 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.4 001165315.1_46928001_3 - 8.4e-06 26.1 1.1 1.1e-05 25.8 0.1 1.7 2 0 0 2 2 1 1 Tetratricopeptide repeat zf-C2H2_jaz PF12171.6 001165315.1_46928001_3 - 0.00013 22.1 3.2 0.00038 20.6 3.2 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding TPR_2 PF07719.15 001165315.1_46928001_3 - 0.00078 19.2 0.3 4.9 7.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.4 001165315.1_46928001_3 - 0.0038 17.2 1.8 0.17 12.1 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C2H2_2 PF12756.5 001165315.1_46928001_3 - 0.0042 17.3 1.1 0.016 15.4 1.1 2.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) ANAPC3 PF12895.5 001165315.1_46928001_3 - 0.02 14.9 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-CCCH PF00642.22 001165315.1_46928001_3 - 0.027 14.3 0.8 0.027 14.3 0.8 4.8 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-met PF12874.5 001165315.1_46928001_3 - 0.08 13.2 3.5 0.35 11.2 3.5 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type TPR_12 PF13424.4 001165315.1_46928001_3 - 0.14 12.3 3.2 2.9 8.1 1.7 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.4 001165315.1_46928001_3 - 0.18 12.5 0.8 5 8.1 0.6 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.4 001165315.1_46928001_3 - 1.7 9.1 4.6 0.24 11.7 0.2 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat Tmemb_18A PF09771.7 001141446.2_46922001_2 - 6.3e-57 190.9 0.0 8.2e-57 190.6 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 188 KapB PF08810.8 001141446.2_46922001_2 - 0.076 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase associated protein B YchF-GTPase_C PF06071.11 001165356.1_46925001_2 - 2e-39 133.5 0.4 2e-39 133.5 0.4 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.21 001165356.1_46925001_2 - 1.7e-22 79.5 0.0 4.5e-22 78.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.16 001165356.1_46925001_2 - 5.4e-07 29.1 0.0 9.4e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.19 001165356.1_46925001_2 - 0.00075 19.4 0.0 0.0021 18.0 0.0 1.7 2 0 0 2 2 2 1 TGS domain ArgK PF03308.14 001165356.1_46925001_2 - 0.023 13.6 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein FERM_C PF09380.8 001165400.1_46927001_2 - 1.7e-20 73.1 0.0 2.9e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.16 001165400.1_46927001_2 - 2.2e-16 60.2 0.1 4.8e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.8 001165400.1_46927001_2 - 8.7e-15 54.3 0.1 2.2e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.9 001165400.1_46927001_2 - 1.2e-12 47.6 12.7 2.3e-12 46.6 12.7 1.6 1 0 0 1 1 1 1 FERM adjacent (FA) ACBP PF00887.17 001165400.1_46927001_2 - 0.015 15.4 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Acyl CoA binding protein FA_desaturase PF00487.22 001171780.1_46926001_1 - 1.1e-35 123.6 29.5 1.1e-35 123.6 29.5 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.26 001171780.1_46926001_1 - 8.7e-21 73.7 0.0 1.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GH-E PF14410.4 001171780.1_46926001_1 - 6.4 7.1 7.5 0.51 10.6 1.0 2.1 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Peptidase_C78 PF07910.11 001173714.1_46928001_1 - 1.3e-65 220.7 0.0 1.9e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 zf-C2H2_4 PF13894.4 001173714.1_46928001_1 - 0.012 16.3 8.3 0.33 11.8 1.6 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger DDRGK PF09756.7 001173714.1_46928001_1 - 0.017 14.6 4.3 0.026 14.0 4.3 1.1 1 0 0 1 1 1 0 DDRGK domain zf-C2H2 PF00096.24 001173714.1_46928001_1 - 0.16 12.3 6.0 2.4 8.7 0.9 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type HSP20 PF00011.19 001141294.1_46922001_1 - 9.5e-15 54.5 0.1 1.5e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GH3 PF03321.11 001173755.1_46926001_3 - 2e-149 498.7 0.0 2.4e-149 498.5 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Acyl-CoA_dh_1 PF00441.22 001141719.1_46924001_2 - 2.2e-37 128.4 0.1 3.4e-37 127.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.17 001141719.1_46924001_2 - 9.2e-24 83.3 0.1 1.6e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.14 001141719.1_46924001_2 - 8.5e-23 81.0 0.0 1.6e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.9 001141719.1_46924001_2 - 2e-10 40.9 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.6 001141719.1_46924001_2 - 0.0016 18.0 0.0 0.0042 16.6 0.0 1.6 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal SNAP PF14938.4 001141047.1_46923001_3 - 7.5e-108 360.1 19.6 9e-108 359.8 19.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.4 001141047.1_46923001_3 - 2.2e-09 37.3 12.3 4.6e-05 23.5 0.5 3.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.4 001141047.1_46923001_3 - 2.5e-06 27.0 4.8 0.32 11.0 0.1 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat NSF PF02071.18 001141047.1_46923001_3 - 0.00013 21.9 33.2 0.78 10.6 2.7 8.7 7 2 2 9 9 9 1 Aromatic-di-Alanine (AdAR) repeat Spatacsin_C PF14649.4 001141047.1_46923001_3 - 0.00043 19.4 8.5 0.029 13.4 2.5 2.4 1 1 1 2 2 2 2 Spatacsin C-terminus TPR_6 PF13174.4 001141047.1_46923001_3 - 0.00049 20.4 12.2 0.82 10.3 0.0 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.4 001141047.1_46923001_3 - 0.00069 19.5 11.0 1.4 9.2 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.15 001141047.1_46923001_3 - 0.0007 19.4 17.4 0.45 10.6 0.0 5.6 4 1 3 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.26 001141047.1_46923001_3 - 0.0072 16.0 15.3 0.39 10.5 0.1 5.0 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.4 001141047.1_46923001_3 - 0.011 16.3 3.2 1.4 9.6 1.7 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2989 PF11207.6 001141047.1_46923001_3 - 0.017 14.7 3.1 0.047 13.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) Lant_dehydr_C PF14028.4 001141047.1_46923001_3 - 0.025 14.0 0.2 0.034 13.6 0.2 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Sel1 PF08238.10 001141047.1_46923001_3 - 0.23 12.1 3.4 8.1 7.2 0.1 3.5 4 0 0 4 4 3 0 Sel1 repeat TPR_14 PF13428.4 001141047.1_46923001_3 - 0.3 11.9 10.6 47 5.0 0.0 5.5 5 2 2 7 7 4 0 Tetratricopeptide repeat YfdX PF10938.6 001141047.1_46923001_3 - 0.48 10.2 4.8 2.9 7.7 1.0 2.6 2 0 0 2 2 2 0 YfdX protein FRB_dom PF08771.9 001141047.1_46923001_3 - 0.52 10.6 3.5 4.8 7.5 0.2 3.4 1 1 2 3 3 3 0 FKBP12-rapamycin binding domain RPN7 PF10602.7 001141047.1_46923001_3 - 1.7 8.2 7.9 2.5 7.6 3.0 2.7 1 1 2 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.4 001141047.1_46923001_3 - 2.7 7.9 11.8 24 4.9 0.0 5.1 5 1 2 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.4 001141047.1_46923001_3 - 2.7 8.4 15.0 8.6 6.8 3.3 4.3 3 2 1 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.4 001141047.1_46923001_3 - 5.2 6.7 18.5 3.4 7.3 0.2 4.9 4 1 1 5 5 5 0 TPR repeat TPR_3 PF07720.10 001141047.1_46923001_3 - 5.5 7.0 11.7 22 5.0 1.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat PDGF PF00341.15 001140636.1_46923001_1 - 1.7e-21 76.2 9.0 1.7e-21 76.2 9.0 2.0 2 0 0 2 2 2 1 PDGF/VEGF domain Ras PF00071.20 001140207.1_46926001_1 - 1.7e-44 151.1 0.3 2.3e-44 150.7 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001140207.1_46926001_1 - 8.3e-15 54.9 0.1 1.2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001140207.1_46926001_1 - 4.5e-05 22.9 0.0 7.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001140207.1_46926001_1 - 0.00072 19.5 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.8 001140207.1_46926001_1 - 0.0021 17.4 0.1 0.0046 16.3 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.25 001140207.1_46926001_1 - 0.0033 16.9 0.5 0.013 14.9 0.3 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001140207.1_46926001_1 - 0.058 13.2 0.1 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Homeobox PF00046.27 001141667.1_46922001_1 - 6.4e-21 73.8 7.9 1.2e-20 73.0 7.9 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001141667.1_46922001_1 - 0.24 11.2 1.5 0.45 10.3 0.9 1.8 2 0 0 2 2 2 0 Homeobox KN domain CENP-H PF05837.10 001146471.1_46923001_3 - 8e-26 90.5 3.6 8e-26 90.5 3.6 1.7 2 0 0 2 2 2 1 Centromere protein H (CENP-H) IncA PF04156.12 001146471.1_46923001_3 - 0.089 12.4 3.0 0.12 12.0 3.0 1.3 1 0 0 1 1 1 0 IncA protein CorA PF01544.16 001146471.1_46923001_3 - 0.83 8.8 3.1 1.3 8.1 3.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ras PF00071.20 001141323.1_46922001_1 - 2.6e-31 108.3 0.1 4.3e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001141323.1_46922001_1 - 6.8e-24 84.3 0.3 1.1e-23 83.6 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001141323.1_46922001_1 - 1.5e-09 37.4 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001141323.1_46922001_1 - 0.00085 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001141323.1_46922001_1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001141323.1_46922001_1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.14 001141323.1_46922001_1 - 0.026 14.3 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.4 001141323.1_46922001_1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain VirE PF05272.9 001141323.1_46922001_1 - 0.067 12.8 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_16 PF13191.4 001141323.1_46922001_1 - 0.069 13.4 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.12 001141323.1_46922001_1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.4 001141323.1_46922001_1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PH PF00169.27 001141323.1_46922001_1 - 0.14 12.6 0.1 0.25 11.7 0.0 1.4 2 0 0 2 2 1 0 PH domain Ribosomal_S13_N PF08069.10 001139592.1_46922001_2 - 2e-32 110.9 0.1 3.4e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.20 001139592.1_46922001_2 - 1.9e-15 56.7 1.9 2.9e-15 56.1 1.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.16 001139592.1_46922001_2 - 0.045 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain SNN_linker PF09050.8 001173624.1_46928001_3 - 1.1e-15 56.9 2.7 2.1e-15 56.0 2.7 1.5 1 0 0 1 1 1 1 Stannin unstructured linker SNN_transmemb PF09049.8 001173624.1_46928001_3 - 1.8e-15 56.4 8.8 3.4e-15 55.5 8.8 1.4 1 0 0 1 1 1 1 Stannin transmembrane SNN_cytoplasm PF09051.8 001173624.1_46928001_3 - 5.1e-13 48.5 0.6 5.1e-13 48.5 0.6 1.7 2 0 0 2 2 2 1 Stannin cytoplasmic Sugar_tr PF00083.22 001173883.1_46926001_3 - 4.2e-149 497.1 19.7 5.3e-149 496.8 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001173883.1_46926001_3 - 2.1e-20 72.9 32.5 2.7e-19 69.2 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.11 001173883.1_46926001_3 - 0.00071 18.0 2.9 0.00071 18.0 2.9 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2626 PF11117.6 001173883.1_46926001_3 - 1.1 9.9 7.7 5.5 7.7 7.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2626) Ig_J_chain PF15097.4 204263.1_23524001_3 - 3.7e-68 227.4 5.4 5.7e-68 226.8 5.4 1.2 1 0 0 1 1 1 1 Immunoglobulin J chain Fascin PF06268.11 001178132.1_23523001_1 - 2.6e-115 378.4 0.4 6.5e-34 116.4 0.0 4.0 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.10 001178132.1_23523001_1 - 3.3e-20 72.5 0.6 0.00027 20.6 0.0 5.8 2 1 4 6 6 6 5 FRG1-like domain DUF569 PF04601.11 001178132.1_23523001_1 - 2.5e-05 23.9 0.2 0.029 13.9 0.0 3.4 2 1 2 4 4 4 3 Domain of unknown function (DUF569) FGF PF00167.16 001178132.1_23523001_1 - 0.0011 18.9 0.0 0.89 9.5 0.0 3.0 2 1 0 2 2 2 2 Fibroblast growth factor RicinB_lectin_2 PF14200.4 001178132.1_23523001_1 - 0.02 15.5 1.6 1.4 9.6 0.0 3.8 3 2 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like 7tm_1 PF00001.19 001031479.1_23523001_1 - 1.9e-43 148.5 23.9 2.3e-43 148.2 23.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001031479.1_23523001_1 - 0.00086 18.6 24.2 0.0016 17.7 24.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF543 PF04418.10 001031479.1_23523001_1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) SPC25 PF06703.9 001031479.1_23523001_1 - 1 9.0 5.3 0.52 9.9 2.2 2.0 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Homeobox_KN PF05920.9 001030336.1_23523001_1 - 8.9e-16 57.4 1.1 1.6e-15 56.5 0.4 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.27 001030336.1_23523001_1 - 1.9e-07 30.7 0.6 3.8e-07 29.7 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain MRP-S32 PF10210.7 001030336.1_23523001_1 - 0.0032 17.9 1.7 0.0033 17.8 0.3 1.7 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S32 FAM176 PF14851.4 001030336.1_23523001_1 - 0.16 11.5 7.8 1 8.9 0.5 2.3 2 0 0 2 2 2 0 FAM176 family BUD22 PF09073.8 001030336.1_23523001_1 - 0.33 10.1 10.8 0.5 9.5 10.8 1.2 1 0 0 1 1 1 0 BUD22 PGA2 PF07543.10 001030336.1_23523001_1 - 6.9 6.5 12.2 0.26 11.1 0.6 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 SDA1 PF05285.10 001030336.1_23523001_1 - 7.9 5.7 13.7 12 5.0 13.7 1.2 1 0 0 1 1 1 0 SDA1 DHHA1 PF02272.17 102411.1_23522120_2 - 0.27 11.2 6.7 0.77 9.7 6.7 1.7 1 0 0 1 1 1 0 DHHA1 domain EF-hand_1 PF00036.30 102411.1_23522120_3 - 2.5e-31 104.7 13.1 1.2e-09 36.8 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 102411.1_23522120_3 - 6e-27 91.1 2.9 3.6e-09 35.7 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.4 102411.1_23522120_3 - 3e-24 85.2 8.5 6.1e-16 58.5 1.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 102411.1_23522120_3 - 3e-23 81.2 8.9 3.1e-13 49.2 0.9 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.4 102411.1_23522120_3 - 9.2e-22 75.4 10.2 1.1e-08 34.0 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.4 102411.1_23522120_3 - 5.7e-09 36.0 0.3 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.7 102411.1_23522120_3 - 0.00027 21.1 0.0 0.053 13.7 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.11 102411.1_23522120_3 - 0.0062 16.3 0.0 0.6 9.9 0.0 2.3 2 1 0 2 2 2 1 Caleosin related protein EF-hand_4 PF12763.5 102411.1_23522120_3 - 0.0063 16.3 2.7 0.086 12.7 0.2 2.6 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Prefoldin_3 PF13758.4 102411.1_23522120_3 - 0.015 15.2 0.0 1.4 8.9 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit DIMCO_N PF16844.3 102411.1_23522120_3 - 0.026 14.7 0.1 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal DUF3349 PF11829.6 102411.1_23522120_3 - 0.029 15.0 0.0 1.1 9.9 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) GPHH PF16905.3 102411.1_23522120_3 - 0.035 13.8 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated TerB PF05099.11 102411.1_23522120_3 - 0.043 13.6 0.2 2.8 7.8 0.0 2.4 2 1 0 2 2 2 0 Tellurite resistance protein TerB OST-HTH PF12872.5 102411.1_23522120_3 - 0.045 13.5 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Dockerin_1 PF00404.16 102411.1_23522120_3 - 1.7 8.5 5.6 13 5.7 0.1 2.7 3 0 0 3 3 3 0 Dockerin type I repeat Ribosomal_L11_N PF03946.12 102416.1_23522120_1 - 2.4e-25 87.9 0.1 3.6e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.17 102416.1_23522120_3 - 3.3e-18 65.8 0.1 5.5e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ctf8 PF09696.8 102418.1_23523120_1 - 1.4e-06 28.5 0.7 0.00013 22.2 0.3 3.0 2 1 0 2 2 2 1 Ctf8 Ctf8 PF09696.8 102419.1_23523120_2 - 1.5e-06 28.5 0.7 0.00013 22.2 0.3 3.0 2 1 0 2 2 2 1 Ctf8 Peptidase_C12 PF01088.19 131183.1_23524120_3 - 5.2e-71 238.6 0.0 6.3e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Alpha-amylase PF00128.22 003250.2_23523120_3 - 0.016 14.6 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Orn_Arg_deC_N PF02784.14 001291591.1_22528001_1 - 9.7e-64 215.0 0.0 1.3e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291591.1_22528001_1 - 3.9e-22 78.3 0.0 7.2e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF4617 PF15395.4 001291591.1_22528001_2 - 0.21 9.7 0.0 0.29 9.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) RNase_H PF00075.22 001285880.1_22524001_3 - 2.5e-45 154.0 0.0 5.2e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285880.1_22524001_3 - 2e-18 66.3 2.7 3.9e-18 65.3 2.7 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285880.1_22524001_3 - 0.00011 21.7 0.0 0.00031 20.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase-like P5CR_dimer PF14748.4 001292084.1_22523001_1 - 3.8e-37 126.6 0.0 8.9e-37 125.4 0.0 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.15 001292084.1_22523001_1 - 6.7e-19 68.1 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.7 001292084.1_22523001_1 - 0.0019 18.0 0.2 0.0041 16.9 0.2 1.5 1 0 0 1 1 1 1 Rossmann-like domain NAD_Gly3P_dh_N PF01210.21 001292084.1_22523001_1 - 0.14 12.0 2.2 0.99 9.2 1.5 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AAA PF00004.27 001293053.1_22523001_1 - 5.3e-43 146.5 0.0 1.4e-42 145.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293053.1_22523001_1 - 2.5e-07 30.8 0.0 6.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293053.1_22523001_1 - 3.3e-06 27.0 0.0 1.7e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293053.1_22523001_1 - 4.7e-06 26.9 0.2 8.1e-05 22.9 0.0 2.6 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293053.1_22523001_1 - 3.6e-05 23.9 0.9 0.0058 16.8 0.2 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293053.1_22523001_1 - 0.0001 21.5 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293053.1_22523001_1 - 0.0017 17.3 0.0 0.0034 16.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.4 001293053.1_22523001_1 - 0.0019 18.2 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.15 001293053.1_22523001_1 - 0.002 17.8 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.4 001293053.1_22523001_1 - 0.0029 18.0 0.3 0.022 15.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.19 001293053.1_22523001_1 - 0.0069 15.7 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.9 001293053.1_22523001_1 - 0.0069 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.11 001293053.1_22523001_1 - 0.0095 15.2 0.0 0.026 13.8 0.0 1.7 1 0 0 1 1 1 1 KaiC PhoH PF02562.14 001293053.1_22523001_1 - 0.011 15.1 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein RILP PF11461.6 001293053.1_22523001_1 - 0.02 14.9 3.4 0.055 13.5 3.4 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_28 PF13521.4 001293053.1_22523001_1 - 0.021 14.9 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.24 001293053.1_22523001_1 - 0.026 14.1 0.1 0.11 12.1 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293053.1_22523001_1 - 0.029 14.0 0.0 0.081 12.5 0.0 1.8 1 1 1 2 2 2 0 AAA domain TsaE PF02367.15 001293053.1_22523001_1 - 0.046 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293053.1_22523001_1 - 0.05 12.6 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.11 001293053.1_22523001_1 - 0.057 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.4 001293053.1_22523001_1 - 0.057 12.8 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.4 001293053.1_22523001_1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.4 001293053.1_22523001_1 - 0.064 12.8 0.4 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.20 001293053.1_22523001_1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.4 001293053.1_22523001_1 - 0.089 13.1 0.6 0.51 10.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.10 001293053.1_22523001_1 - 0.12 11.5 0.0 0.33 10.1 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.4 001293053.1_22523001_1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain SlyX PF04102.10 001293053.1_22523001_1 - 0.16 12.4 2.3 0.55 10.8 2.3 1.9 1 0 0 1 1 1 0 SlyX Laminin_II PF06009.10 001293053.1_22523001_1 - 0.25 11.2 3.7 1.3 8.9 1.0 2.7 3 0 0 3 3 3 0 Laminin Domain II MscS_porin PF12795.5 001293053.1_22523001_1 - 7.6 5.9 12.7 12 5.2 12.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Orn_Arg_deC_N PF02784.14 001293744.1_22525001_1 - 1.6e-62 211.0 0.0 2e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293744.1_22525001_1 - 2.9e-13 49.8 0.0 5.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-C4 PF00105.16 001323206.1_13923001_2 - 3.4e-29 101.0 13.9 5.6e-29 100.3 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001323206.1_13923001_2 - 4.2e-19 68.8 0.9 9.8e-19 67.6 0.9 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Filament PF00038.19 001323494.1_23924001_1 - 1.1e-109 366.7 50.4 1.3e-109 366.5 50.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.12 001323494.1_23924001_1 - 1.5e-10 41.7 3.0 4.9e-10 40.0 3.0 1.9 1 0 0 1 1 1 1 Intermediate filament head (DNA binding) region TolA_bind_tri PF16331.3 001323494.1_23924001_1 - 0.0074 16.2 4.3 0.0074 16.2 4.3 4.5 3 2 1 4 4 4 2 TolA binding protein trimerisation Reo_sigmaC PF04582.10 001323494.1_23924001_1 - 0.026 13.8 12.1 0.084 12.1 2.0 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.10 001323494.1_23924001_1 - 0.086 12.7 18.9 0.11 12.4 0.3 3.3 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.7 001323494.1_23924001_1 - 0.81 9.0 39.9 1.2 8.4 22.0 2.3 1 1 0 2 2 2 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.10 001323494.1_23924001_1 - 2.7 7.9 47.4 1.6 8.6 17.1 4.4 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein T2SSF PF00482.21 001323494.1_23924001_1 - 3.9 7.3 12.3 0.064 13.1 2.7 2.7 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F Fib_alpha PF08702.8 001323494.1_23924001_1 - 4.2 7.4 26.3 0.22 11.6 3.7 3.1 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.7 001323494.1_23924001_1 - 4.4 7.2 42.3 1.2 9.0 8.3 3.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.7 001323494.1_23924001_1 - 5.6 7.0 44.8 0.76 9.8 15.8 3.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.10 001323494.1_23924001_1 - 9 6.2 20.4 1.9 8.4 3.9 3.9 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.23 001323490.1_23923001_1 - 2e-68 230.5 0.0 2.4e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001323490.1_23923001_1 - 5.1e-24 84.8 0.0 7e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001323490.1_23923001_1 - 7.6e-05 22.0 0.0 0.00048 19.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001323490.1_23923001_1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.12 001323490.1_23923001_1 - 0.031 13.5 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.14 001323490.1_23923001_1 - 0.088 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Transferrin PF00405.15 001291386.1_45425001_1 - 1.4e-194 645.5 7.9 6.9e-121 403.3 0.2 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.5 001291386.1_45425001_1 - 1.1e-11 44.7 0.0 1.9e-05 24.3 0.0 3.1 3 0 0 3 3 3 3 ABC transporter, phosphonate, periplasmic substrate-binding protein Glyco_transf_29 PF00777.16 001319649.1_45423001_1 - 4.9e-83 278.5 0.0 6.5e-83 278.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.19 001319649.1_45423001_1 - 0.0052 15.5 0.0 0.0076 14.9 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1660 PF07874.9 001319649.1_45423001_1 - 0.012 16.0 0.0 0.74 10.2 0.0 2.4 2 0 0 2 2 2 0 Prophage protein (DUF1660) Ribonuc_red_sm PF00268.19 001319649.1_45423001_1 - 0.034 13.5 0.9 0.051 12.9 0.9 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain Orn_Arg_deC_N PF02784.14 001291786.2_45427001_3 - 1.4e-57 194.8 0.0 1.8e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291786.2_45427001_3 - 1.9e-19 69.7 0.0 3.7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AAA PF00004.27 001293087.1_45423001_3 - 5.4e-43 146.4 0.0 1.2e-42 145.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293087.1_45423001_3 - 2.2e-07 31.0 0.0 5.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293087.1_45423001_3 - 2.9e-06 27.2 0.0 1.6e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293087.1_45423001_3 - 4.3e-06 27.1 0.2 7.6e-05 23.0 0.0 2.6 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293087.1_45423001_3 - 2e-05 24.7 1.2 0.0054 16.9 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293087.1_45423001_3 - 9.6e-05 21.6 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293087.1_45423001_3 - 0.0015 17.4 0.0 0.0032 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293087.1_45423001_3 - 0.0017 18.0 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293087.1_45423001_3 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293087.1_45423001_3 - 0.0024 18.2 0.2 0.02 15.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.9 001293087.1_45423001_3 - 0.0063 16.2 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.19 001293087.1_45423001_3 - 0.0065 15.7 0.1 0.016 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.14 001293087.1_45423001_3 - 0.0078 15.6 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein ATPase PF06745.11 001293087.1_45423001_3 - 0.0084 15.4 0.0 0.024 13.9 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.4 001293087.1_45423001_3 - 0.019 15.0 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293087.1_45423001_3 - 0.023 14.8 3.4 0.052 13.6 3.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293087.1_45423001_3 - 0.023 14.2 0.1 0.1 12.2 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293087.1_45423001_3 - 0.027 14.1 0.0 0.076 12.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain TsaE PF02367.15 001293087.1_45423001_3 - 0.043 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293087.1_45423001_3 - 0.048 12.6 0.0 0.082 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.4 001293087.1_45423001_3 - 0.051 13.0 0.0 0.17 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.4 001293087.1_45423001_3 - 0.052 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.11 001293087.1_45423001_3 - 0.053 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.20 001293087.1_45423001_3 - 0.063 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.4 001293087.1_45423001_3 - 0.068 12.7 0.3 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.4 001293087.1_45423001_3 - 0.085 13.2 0.5 0.48 10.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain HR1 PF02185.14 001293087.1_45423001_3 - 0.12 12.4 5.2 0.35 10.9 5.2 1.8 1 0 0 1 1 1 0 Hr1 repeat AAA_19 PF13245.4 001293087.1_45423001_3 - 0.13 12.5 0.2 0.44 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain Laminin_II PF06009.10 001293087.1_45423001_3 - 0.19 11.6 3.4 1.2 9.0 0.9 2.7 3 0 0 3 3 3 0 Laminin Domain II DivIC PF04977.13 001293087.1_45423001_3 - 0.23 11.1 2.6 0.55 9.9 2.6 1.6 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.10 001293087.1_45423001_3 - 0.31 11.6 2.0 1.1 9.9 2.0 2.0 1 0 0 1 1 1 0 SlyX MscS_porin PF12795.5 001293087.1_45423001_3 - 4.2 6.7 11.6 6.4 6.1 11.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Death PF00531.20 001324179.1_48222001_1 - 1.3e-13 50.8 0.3 3.2e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Death domain TIR PF01582.18 001324179.1_48222001_1 - 1.5e-13 50.8 0.0 2.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.4 001324179.1_48222001_1 - 1.9e-12 47.3 0.0 6.1e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 TIR domain Orn_Arg_deC_N PF02784.14 001293751.1_24024001_2 - 2.8e-61 207.0 0.0 3.4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293751.1_24024001_2 - 0.0026 17.7 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain # # Program: hmmscan # Version: 3.1b2 (February 2015) # Pipeline mode: SCAN # Query file: /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/all_spe/wd/all_spe.p.fa # Target file: /home/yduan/database/Pfam/Pfam-A.hmm # Option settings: hmmscan -o /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/all_spe/hmmscan.outm --tblout /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/all_spe/hmmscan.t.out /home/yduan/database/Pfam/Pfam-A.hmm /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/all_spe/wd/all_spe.p.fa # Current dir: /home/yduan/work_file/lncRNAdb/methods_assement # Date: Sun Jul 8 16:14:52 2018 # [ok]