# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Myticin-prepro PF10690.7 NONMMLT004946.1_29611102_1 - 0.18 11.9 5.5 0.29 11.3 5.5 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Cupin_1 PF00190.20 NONMMLT004951.1_29611102_2 - 0.16 11.4 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Cupin zf-C4_Topoisom PF01396.17 NONMMLT004962.1_29612102_3 - 0.084 12.5 0.9 0.15 11.7 0.9 1.4 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger RAM PF15320.4 NONMMLT004968.1_29612102_3 - 0.036 14.5 1.0 0.052 14.0 1.0 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein FancD2 PF14631.4 NONMMLT004985.1_29612102_2 - 7.5e-30 103.1 1.8 9e-30 102.8 1.8 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FancD2 PF14631.4 NONMMLT004985.1_29612102_3 - 2.1e-19 68.4 0.5 2.7e-19 68.1 0.5 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease IL17_R_N PF15037.4 NONMMLT004986.1_29611102_1 - 3.4e-08 32.7 0.2 4.6e-08 32.3 0.2 1.1 1 0 0 1 1 1 1 Interleukin-17 receptor extracellular region zinc-ribbons_6 PF07191.10 NONMMLT005000.1_29612104_3 - 0.065 13.1 0.6 0.093 12.6 0.6 1.3 1 0 0 1 1 1 0 zinc-ribbons OrfB_Zn_ribbon PF07282.9 NONMMLT005000.1_29612104_3 - 0.45 10.3 2.6 0.87 9.4 2.6 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain LRRNT PF01462.16 NONMMLT005034.1_29612102_1 - 0.95 9.1 9.1 2.7 7.6 9.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain TMA7 PF09072.8 NONMMLT005046.1_29612118_2 - 2.4e-08 34.5 3.8 2.4e-08 34.5 3.8 2.9 3 0 0 3 3 3 1 Translation machinery associated TMA7 SRP40_C PF05022.10 NONMMLT005046.1_29612118_2 - 0.36 11.6 4.9 0.71 10.6 4.9 1.4 1 0 0 1 1 1 0 SRP40, C-terminal domain TMA7 PF09072.8 NONMMLT005046.1_29612118_3 - 9.2e-13 48.7 13.4 9.2e-13 48.7 13.4 2.0 2 0 0 2 2 2 1 Translation machinery associated TMA7 TMA7 PF09072.8 NONMMLT005048.1_29612118_2 - 2.4e-08 34.5 3.8 2.4e-08 34.5 3.8 2.0 2 0 0 2 2 2 1 Translation machinery associated TMA7 TMA7 PF09072.8 NONMMLT005048.1_29612118_3 - 1.1e-10 42.0 5.0 1.8e-10 41.3 5.0 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 TMA7 PF09072.8 NONMMLT005049.1_29611118_1 - 8.9e-10 39.1 5.6 1.3e-09 38.6 5.6 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 TMA7 PF09072.8 NONMMLT005049.1_29611118_3 - 1.5e-09 38.4 7.2 2e-09 38.0 7.2 1.3 1 0 0 1 1 1 1 Translation machinery associated TMA7 PTCB-BRCT PF12738.5 NONMMLT005051.1_29612102_2 - 0.16 11.8 0.0 21 5.0 0.0 2.1 2 0 0 2 2 2 0 twin BRCT domain Ribosomal_L14e PF01929.15 NONMMLT005054.1_29611102_2 - 4e-21 75.2 10.5 5.6e-21 74.7 10.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 DUF1220 PF06758.11 NONMMLT005062.1_29611104_3 - 2.2e-17 63.0 3.3 2.2e-17 63.0 3.3 2.0 2 0 0 2 2 2 1 Repeat of unknown function (DUF1220) DUF3795 PF12675.5 NONMMLT005062.1_29611104_3 - 0.044 14.0 0.1 0.083 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) zf-U11-48K PF05253.10 NONMMLT005063.1_29613104_1 - 9.6 6.1 6.8 31 4.5 0.7 2.4 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger LRR_9 PF14580.4 NONMMLT005097.1_29613102_2 - 1.6e-05 24.3 1.1 2.7e-05 23.6 1.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.4 NONMMLT005097.1_29613102_2 - 0.00064 19.3 6.3 0.0061 16.2 0.6 2.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.5 NONMMLT005097.1_29613102_2 - 0.00069 19.8 5.8 0.0059 16.8 0.3 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) DUF4675 PF15720.3 NONMMLT005118.1_29612102_2 - 0.015 14.9 0.2 0.028 14.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) Cons_hypoth95 PF03602.13 NONMMLT005118.1_29612102_2 - 0.14 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 VP_N-CPKC PF11475.6 NONMMLT005187.1_29614102_1 - 0.0036 17.0 0.4 0.01 15.6 0.4 1.7 1 0 0 1 1 1 1 Virion protein N terminal domain DUF389 PF04087.12 NONMMLT005187.1_29614102_3 - 0.32 10.9 1.7 0.5 10.3 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF389) DUF389 PF04087.12 NONMMLT005188.1_29611102_1 - 0.036 14.0 1.7 0.057 13.3 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF389) SNARE PF05739.17 NONMMLT005240.1_29611102_2 - 3.9e-14 52.2 5.6 7.1e-14 51.4 5.6 1.5 1 1 0 1 1 1 1 SNARE domain DUF3671 PF12420.6 NONMMLT005240.1_29611102_2 - 0.00043 20.2 0.4 0.00055 19.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function Rax2 PF12768.5 NONMMLT005240.1_29611102_2 - 0.019 14.4 0.4 0.022 14.2 0.4 1.0 1 0 0 1 1 1 0 Cortical protein marker for cell polarity ETRAMP PF09716.8 NONMMLT005240.1_29611102_2 - 0.024 14.6 3.1 0.03 14.2 2.7 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) LRRC37AB_C PF14914.4 NONMMLT005240.1_29611102_2 - 0.039 13.7 0.8 0.045 13.5 0.8 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain COG2 PF06148.9 NONMMLT005240.1_29611102_2 - 0.067 13.1 0.8 0.08 12.9 0.8 1.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sigma_reg_N PF13800.4 NONMMLT005240.1_29611102_2 - 0.088 13.0 2.0 0.13 12.5 2.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF1510 PF07423.9 NONMMLT005240.1_29611102_2 - 0.11 11.8 2.1 0.13 11.5 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Prok-RING_1 PF14446.4 NONMMLT005276.1_29611102_2 - 0.045 13.5 0.9 0.074 12.9 0.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Prok-RING_1 PF14446.4 NONMMLT005277.1_29611102_1 - 0.04 13.7 0.9 0.065 13.0 0.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RB_A PF01858.15 NONMMLT005281.1_29613102_1 - 9.6e-40 136.4 0.6 3.2e-39 134.7 0.3 1.9 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.18 NONMMLT005281.1_29613102_1 - 1.3e-30 106.0 2.8 2.5e-30 105.1 2.8 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain TFIIA PF03153.11 NONMMLT005281.1_29613102_1 - 0.38 10.6 4.9 0.49 10.2 4.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRRCT PF01463.22 NONMMLT005332.1_29611104_2 - 2.2e-05 24.5 0.8 0.00013 22.1 0.1 2.5 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain WSC PF01822.17 NONMMLT005332.1_29611104_2 - 0.0074 16.3 0.5 0.012 15.7 0.0 1.6 2 0 0 2 2 2 1 WSC domain TPKR_C2 PF16920.3 NONMMLT005332.1_29611104_2 - 0.015 15.2 0.3 0.03 14.3 0.3 1.6 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain DUF4644 PF15486.4 NONMMLT005343.1_29613102_2 - 1e-84 282.0 10.0 1.6e-84 281.4 10.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4644) HLH PF00010.24 NONMMLT005346.1_29612102_2 - 1.5e-17 63.2 0.2 3.5e-17 62.0 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.3 NONMMLT005346.1_29612102_2 - 0.00066 19.2 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain CortBP2 PF09727.7 NONMMLT005346.1_29612102_2 - 0.016 15.0 0.8 0.027 14.2 0.8 1.3 1 1 0 1 1 1 0 Cortactin-binding protein-2 WD40 PF00400.30 NONMMLT005350.1_29611102_2 - 1.6e-05 25.5 0.2 4e-05 24.2 0.2 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF1899 PF08953.9 NONMMLT005350.1_29611102_2 - 0.00074 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Lipoprotein_3 PF00938.15 NONMMLT005366.1_29612102_1 - 0.1 12.7 0.3 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein Gag_MA PF01140.17 NONMMLT005371.1_29613102_2 - 1.2e-10 41.1 0.0 1.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Matrix protein (MA), p15 Sushi PF00084.18 NONMMLT005389.1_29612102_3 - 3.1e-09 37.2 0.7 5.4e-09 36.4 0.7 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) CUB PF00431.18 NONMMLT005389.1_29612102_3 - 0.00042 20.5 0.0 0.0006 20.0 0.0 1.2 1 0 0 1 1 1 1 CUB domain ERbeta_N PF12497.6 NONMMLT005393.1_29615102_1 - 0.36 10.5 4.4 3.4 7.3 1.5 3.1 2 1 0 2 2 2 0 Estrogen receptor beta Adeno_E1B_55K_N PF04623.10 NONMMLT005415.1_29611102_1 - 1.1 9.9 12.4 1.7 9.3 12.4 1.2 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus A_amylase_inhib PF01356.17 NONMMLT005451.1_29615104_2 - 0.1 12.5 1.1 0.22 11.4 1.1 1.5 1 0 0 1 1 1 0 Alpha amylase inhibitor Herpes_BTRF1 PF04682.10 NONMMLT005466.1_29612102_1 - 0.08 12.1 0.6 0.11 11.7 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region DUF3577 PF12101.6 NONMMLT005467.1_29612102_3 - 0.1 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) DUF3311 PF11755.6 NONMMLT005496.1_29611117_1 - 0.042 13.7 0.3 0.58 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Protocadherin PF08374.9 NONMMLT005496.1_29611117_3 - 7.9 6.3 5.8 10 5.9 5.8 1.1 1 0 0 1 1 1 0 Protocadherin VPS9 PF02204.16 NONMMLT005504.1_29612102_3 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain Golgin_A5 PF09787.7 NONMMLT005614.1_29611102_2 - 0.0068 15.8 10.5 0.0078 15.6 10.5 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 SOR_SNZ PF01680.15 NONMMLT005614.1_29611102_2 - 0.014 15.1 1.2 0.017 14.8 1.2 1.0 1 0 0 1 1 1 0 SOR/SNZ family Stathmin PF00836.17 NONMMLT005614.1_29611102_2 - 0.014 15.2 9.6 0.019 14.8 9.6 1.1 1 0 0 1 1 1 0 Stathmin family zf-C4H2 PF10146.7 NONMMLT005614.1_29611102_2 - 0.66 10.1 10.4 0.69 10.0 10.4 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.12 NONMMLT005614.1_29611102_2 - 0.88 9.2 14.1 0.94 9.1 14.1 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.7 NONMMLT005614.1_29611102_2 - 2.5 7.0 12.0 2.6 6.9 12.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP-synt_DE PF00401.18 NONMMLT005614.1_29611102_2 - 3.8 7.7 15.1 7.1 6.9 3.5 2.4 1 1 1 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain FlaC_arch PF05377.9 NONMMLT005614.1_29611102_2 - 4.3 7.7 6.6 1.9 8.8 1.0 2.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.11 NONMMLT005614.1_29611102_2 - 5.3 6.1 6.4 5.6 6.0 6.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Zein-binding PF04576.13 NONMMLT005614.1_29611102_2 - 7 6.9 18.9 2.5 8.3 12.9 2.1 1 1 1 2 2 2 0 Zein-binding APG6 PF04111.10 NONMMLT005614.1_29611102_2 - 7.5 5.7 12.7 8.3 5.6 12.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 dUTPase PF00692.17 NONMMLT005635.1_29613102_2 - 4e-09 36.1 0.0 5.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 dUTPase DUF4692 PF15763.3 NONMMLT005635.1_29613102_3 - 0.015 15.7 0.1 0.022 15.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4692) EF-hand_2 PF09068.9 NONMMLT005658.1_29613102_2 - 0.079 13.0 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 EF hand TBCC PF07986.10 NONMMLT005693.1_29612102_2 - 0.076 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C PEX-2N PF09263.8 NONMMLT005719.1_29614102_3 - 7.8e-29 99.6 1.0 1.9e-19 69.5 0.1 2.6 2 0 0 2 2 2 2 Peroxisome biogenesis factor 1, N-terminal PEX-1N PF09262.9 NONMMLT005719.1_29614102_3 - 9.3e-26 89.9 0.8 2.7e-25 88.5 0.8 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PNGaseA PF12222.6 NONMMLT005719.1_29614102_3 - 0.01 14.6 1.0 0.015 14.0 1.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF2870 PF11069.6 NONMMLT005719.1_29614102_3 - 3.3 8.0 6.8 0.67 10.2 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) PEX-2N PF09263.8 NONMMLT005720.1_29614102_1 - 1e-19 70.4 0.1 1.7e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PEX-1N PF09262.9 NONMMLT005720.1_29614102_1 - 0.0023 18.2 0.1 0.0045 17.3 0.1 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PEX-1N PF09262.9 NONMMLT005720.1_29614102_3 - 2.2e-14 53.5 0.5 4.2e-14 52.6 0.1 1.7 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal PNGaseA PF12222.6 NONMMLT005720.1_29614102_3 - 0.0096 14.7 1.0 0.013 14.2 1.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF2870 PF11069.6 NONMMLT005720.1_29614102_3 - 3 8.1 6.9 0.61 10.3 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Vps4_C PF09336.8 NONMMLT005725.1_29612102_1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain ATP-synt_F PF01990.15 NONMMLT005766.1_29612102_1 - 5.6e-17 61.7 0.1 7.9e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Thrombin_light PF09396.8 NONMMLT005766.1_29612102_1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Thrombin light chain DUF1987 PF09345.8 NONMMLT005770.1_29611102_2 - 0.081 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Phage_BR0599 PF09356.8 NONMMLT005799.1_29612102_3 - 0.0071 16.6 0.2 4.4 7.6 0.0 2.2 2 0 0 2 2 2 2 Phage conserved hypothetical protein BR0599 TIL PF01826.15 NONMMLT005804.1_29612102_1 - 1.9e-08 34.3 9.3 1.9e-08 34.3 9.3 2.7 2 0 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain TSP_1 PF00090.17 NONMMLT005804.1_29612102_3 - 5e-11 42.5 7.8 5e-11 42.5 7.8 3.1 3 0 0 3 3 3 1 Thrombospondin type 1 domain TIL PF01826.15 NONMMLT005804.1_29612102_3 - 2.7e-08 33.8 13.7 2.7e-08 33.8 13.7 3.9 3 1 1 4 4 4 1 Trypsin Inhibitor like cysteine rich domain YcxB PF14317.4 NONMMLT005829.1_29612102_1 - 0.0027 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 YcxB-like protein LCE6A PF15858.3 NONMMLT005829.1_29612102_2 - 6.7 7.4 11.6 2.3 8.9 5.2 2.5 2 0 0 2 2 2 0 Late cornified envelope protein 6A family ACT_7 PF13840.4 NONMMLT005916.1_29617118_2 - 1.6e-13 50.1 0.0 2.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 ACT domain GTF2I PF02946.12 NONMMLT005924.1_29612102_1 - 5.7e-05 22.9 0.0 9.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 GTF2I-like repeat GTF2I PF02946.12 NONMMLT005924.1_29612102_3 - 0.0011 18.8 0.1 0.98 9.4 0.0 2.2 2 0 0 2 2 2 2 GTF2I-like repeat GTF2I PF02946.12 NONMMLT005925.1_29612102_1 - 0.00084 19.2 0.1 0.87 9.5 0.0 2.2 2 0 0 2 2 2 2 GTF2I-like repeat GTF2I PF02946.12 NONMMLT005925.1_29612102_2 - 5e-05 23.1 0.0 8.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 GTF2I-like repeat Cpn60_TCP1 PF00118.22 NONMMLT005930.1_29613102_1 - 4.6e-15 55.1 0.0 5.6e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Septin PF00735.16 NONMMLT005937.1_29612118_1 - 0.0025 17.0 0.0 0.0025 17.0 0.0 1.4 2 0 0 2 2 2 1 Septin Septin PF00735.16 NONMMLT005938.1_29612118_2 - 0.00016 20.9 1.2 0.00016 20.9 0.0 1.4 2 0 0 2 2 2 1 Septin MSA-2c PF12238.6 NONMMLT005939.1_29613102_1 - 4.9 7.0 6.5 7.2 6.4 6.5 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c PP_kinase PF02503.15 NONMMLT005977.1_29612102_2 - 0.025 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase middle domain SLAM PF06214.9 NONMMLT006012.1_29611102_2 - 0.0073 16.2 0.1 0.0089 15.9 0.1 1.1 1 0 0 1 1 1 1 Signaling lymphocytic activation molecule (SLAM) protein PSI PF01437.23 NONMMLT006031.1_29612102_3 - 0.061 13.7 12.4 0.12 12.8 12.4 1.4 1 0 0 1 1 1 0 Plexin repeat Thioredoxin_2 PF13098.4 NONMMLT006055.1_29611102_1 - 0.0032 17.7 0.4 0.0043 17.4 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain zf-XS PF03470.12 NONMMLT006055.1_29611102_1 - 0.029 14.5 1.7 0.046 13.9 1.7 1.3 1 0 0 1 1 1 0 XS zinc finger domain Thioredoxin_2 PF13098.4 NONMMLT006056.1_29612102_1 - 0.011 16.1 0.6 0.015 15.6 0.6 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain zf-XS PF03470.12 NONMMLT006056.1_29612102_1 - 0.063 13.4 1.7 0.11 12.6 1.7 1.4 1 0 0 1 1 1 0 XS zinc finger domain MRI PF15325.4 NONMMLT006089.1_29612102_1 - 9e-11 42.8 0.1 1.6e-10 41.9 0.1 1.4 1 0 0 1 1 1 1 Modulator of retrovirus infection DENN PF02141.19 NONMMLT006093.1_29611102_3 - 3.1e-26 92.4 2.0 3.5e-26 92.1 2.0 1.0 1 0 0 1 1 1 1 DENN (AEX-3) domain TAFH PF07531.12 NONMMLT006093.1_29611102_3 - 0.0043 16.9 0.1 0.0061 16.4 0.1 1.3 1 0 0 1 1 1 1 NHR1 homology to TAF SPATA3 PF15662.3 NONMMLT006115.1_29612102_3 - 0.04 14.4 1.5 0.069 13.6 1.5 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Toxin_11 PF07473.9 NONMMLT006144.1_29615104_3 - 0.076 13.0 6.5 0.26 11.3 0.5 2.7 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species Pox_A8 PF04745.10 NONMMLT006197.1_29612102_2 - 0.16 10.8 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 VITF-3 subunit protein DUF2706 PF10913.6 NONMMLT006217.1_29611102_3 - 2.1 8.1 8.8 0.5 10.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) dUTPase PF00692.17 NONMMLT006298.1_29612102_1 - 0.0079 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 dUTPase AAA_11 PF13086.4 NONMMLT006315.1_29611102_1 - 0.064 12.8 6.0 0.071 12.7 6.0 1.0 1 0 0 1 1 1 0 AAA domain MAS20 PF02064.13 NONMMLT006315.1_29611102_1 - 0.3 11.0 10.6 0.39 10.7 10.6 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor Rtf2 PF04641.10 NONMMLT006315.1_29611102_1 - 0.34 10.1 13.0 0.4 9.9 13.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Afi1 PF07792.10 NONMMLT006315.1_29611102_1 - 0.36 11.2 8.0 0.45 10.9 8.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3984 PF13136.4 NONMMLT006315.1_29611102_1 - 0.68 9.2 13.1 0.85 8.8 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Spem1 PF15670.3 NONMMLT006315.1_29611102_1 - 1 8.7 8.8 1.2 8.5 8.8 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 RR_TM4-6 PF06459.10 NONMMLT006315.1_29611102_1 - 1.2 8.8 11.6 1.4 8.6 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.15 NONMMLT006315.1_29611102_1 - 1.4 7.5 10.2 1.7 7.2 10.2 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.11 NONMMLT006315.1_29611102_1 - 1.7 7.2 13.7 2 7.0 13.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 V_ATPase_I PF01496.17 NONMMLT006315.1_29611102_1 - 3 5.5 13.3 3.4 5.3 13.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.3 NONMMLT006315.1_29611102_1 - 3.8 6.7 9.4 4.5 6.5 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.14 NONMMLT006315.1_29611102_1 - 5.2 6.9 8.1 6.1 6.7 8.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec62 PF03839.14 NONMMLT006315.1_29611102_1 - 6.2 6.1 13.4 7.8 5.8 13.4 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 CLN3 PF02487.15 NONMMLT006315.1_29611102_1 - 9.8 5.0 5.4 11 4.8 5.4 1.0 1 0 0 1 1 1 0 CLN3 protein dUTPase PF00692.17 NONMMLT006405.1_29612102_1 - 0.0025 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 dUTPase PyrI_C PF02748.13 NONMMLT006409.1_29611102_2 - 0.04 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain LEF-8 PF04941.10 NONMMLT006409.1_29611102_2 - 0.2 9.7 0.0 0.26 9.4 0.0 1.0 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) DUF1087 PF06465.11 NONMMLT006423.1_29616104_1 - 0.16 11.9 0.2 0.28 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Homez PF11569.6 NONMMLT006440.1_29611102_3 - 0.007 15.7 0.2 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF1443 PF07280.9 NONMMLT006472.1_29611102_2 - 0.0069 16.0 0.2 0.01 15.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1443) SCAN PF02023.15 NONMMLT006509.1_29612102_2 - 9.2e-07 28.5 0.8 2.2e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 SCAN domain HCR PF07111.10 NONMMLT006519.1_29613118_1 - 3.7e-24 84.7 0.5 4.6e-24 84.4 0.5 1.0 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) HCR PF07111.10 NONMMLT006521.1_29611118_1 - 1.2e-24 86.3 1.9 1.4e-24 86.1 1.9 1.0 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) TAS2R PF05296.11 NONMMLT006529.1_29611102_1 - 0.33 9.9 0.8 0.43 9.5 0.8 1.0 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) PXT1 PF15214.4 NONMMLT006533.1_29613102_2 - 8e-29 99.6 9.3 1.1e-28 99.2 8.4 1.7 2 0 0 2 2 2 1 Peroxisomal testis-specific protein 1 BID PF06393.9 NONMMLT006533.1_29613102_2 - 0.00085 18.7 0.2 0.0013 18.1 0.2 1.2 1 0 0 1 1 1 1 BH3 interacting domain (BID) Pro_isomerase PF00160.19 NONMMLT006534.1_29611102_1 - 2.2e-10 40.9 0.0 2.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD COX7a PF02238.13 NONMMLT006586.1_29611102_2 - 0.077 13.3 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII MMS22L_N PF14910.4 NONMMLT006613.1_29612102_2 - 2.4e-30 105.5 0.0 2.8e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal Adeno_E3_CR2 PF02439.13 NONMMLT006664.1_29611102_2 - 0.031 13.9 0.8 0.057 13.1 0.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rtf2 PF04641.10 NONMMLT006664.1_29611102_2 - 0.12 11.6 0.5 0.85 8.8 0.1 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger Tubulin-binding PF00418.17 NONMMLT006681.1_29611102_3 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat Sod_Fe_N PF00081.20 NONMMLT006690.1_29611118_1 - 4.2e-07 30.2 0.0 5.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain BCMA-Tall_bind PF09257.8 NONMMLT006713.1_29612102_3 - 4.4 7.3 6.6 2 8.4 0.2 2.9 2 1 1 3 3 3 0 BCMA, TALL-1 binding HAUS4 PF14735.4 NONMMLT006779.1_29611102_2 - 0.0031 17.1 0.1 0.0039 16.8 0.1 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 RNF111_N PF15303.4 NONMMLT006779.1_29611102_2 - 0.021 14.5 1.7 0.021 14.5 1.7 1.3 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Sel1 PF08238.10 NONMMLT006842.1_29612102_3 - 0.021 15.4 0.1 0.039 14.5 0.1 1.4 1 0 0 1 1 1 0 Sel1 repeat TMEM72 PF16054.3 NONMMLT006864.1_29611102_2 - 0.019 14.5 0.3 0.021 14.4 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 DUF1853 PF08907.9 NONMMLT006882.1_29611102_1 - 0.011 15.4 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) DUF1853 PF08907.9 NONMMLT006883.1_29612102_2 - 0.0004 20.0 0.0 0.0005 19.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1853) DUF4722 PF15849.3 NONMMLT006884.1_29613118_1 - 9.8e-95 314.8 0.2 1.2e-94 314.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4722) COX7B PF05392.9 NONMMLT006992.1_29612118_2 - 6.7e-42 140.9 0.1 9.7e-42 140.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB PROL5-SMR PF15621.4 NONMMLT007017.1_29612104_3 - 1.4e-24 86.4 23.8 1.4e-24 86.4 23.8 2.2 2 0 0 2 2 2 1 Proline-rich submaxillary gland androgen-regulated family DUF3079 PF11278.6 NONMMLT007024.1_29611102_3 - 0.45 10.2 3.4 0.25 11.0 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) Endomucin PF07010.10 NONMMLT007039.1_29612102_1 - 3.2e-25 89.5 3.3 4.1e-25 89.1 3.3 1.1 1 0 0 1 1 1 1 Endomucin Endomucin PF07010.10 NONMMLT007041.1_29612102_3 - 1.5e-72 244.5 28.9 1.8e-72 244.3 28.9 1.0 1 0 0 1 1 1 1 Endomucin DUF2207 PF09972.7 NONMMLT007041.1_29612102_3 - 0.54 8.9 5.3 1.1 7.8 5.3 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.23 NONMMLT007046.1_29611102_2 - 0.00015 21.1 0.0 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIX1 PF08167.10 NONMMLT007046.1_29611102_2 - 0.015 15.0 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Pkinase_Tyr PF07714.15 NONMMLT007046.1_29611102_2 - 0.054 12.6 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase DICT PF10069.7 NONMMLT007073.1_29611102_2 - 0.059 13.0 0.1 0.068 12.8 0.1 1.0 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system MT0933_antitox PF14013.4 NONMMLT007187.1_29611102_1 - 0.23 11.7 0.5 0.35 11.1 0.1 1.4 2 0 0 2 2 2 0 MT0933-like antitoxin protein DUF1725 PF08333.9 NONMMLT007237.1_29612102_1 - 4.2e-08 32.5 0.1 6.4e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) S36_mt PF10937.6 NONMMLT007247.1_29612102_2 - 0.02 16.3 1.5 0.59 11.6 1.4 2.2 1 1 0 1 1 1 0 Ribosomal protein S36, mitochondrial COX7C PF02935.14 NONMMLT007267.1_29611118_3 - 9.5e-15 54.5 0.9 1.5e-14 53.8 0.9 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc CYSTM PF12734.5 NONMMLT007334.1_29611117_3 - 4.8e-07 29.9 6.8 6.5e-07 29.5 6.8 1.2 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance PsbX PF06596.9 NONMMLT007360.1_29612102_1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) AAA_13 PF13166.4 NONMMLT007388.1_29611102_2 - 0.00026 19.7 1.3 0.00027 19.6 1.3 1.0 1 0 0 1 1 1 1 AAA domain ASD2 PF08687.9 NONMMLT007388.1_29611102_2 - 0.0047 16.5 13.0 0.0056 16.2 13.0 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 HMMR_N PF15905.3 NONMMLT007388.1_29611102_2 - 0.026 13.9 18.0 0.041 13.2 18.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ADIP PF11559.6 NONMMLT007388.1_29611102_2 - 0.028 14.3 21.2 0.072 13.0 18.5 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YlqD PF11068.6 NONMMLT007388.1_29611102_2 - 0.049 13.9 19.8 0.079 13.2 10.8 2.1 1 1 1 2 2 2 0 YlqD protein DUF4200 PF13863.4 NONMMLT007388.1_29611102_2 - 0.056 13.7 14.3 0.26 11.6 13.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Rab5-bind PF09311.9 NONMMLT007388.1_29611102_2 - 0.083 12.1 20.6 0.027 13.7 8.0 2.0 1 1 1 2 2 2 0 Rabaptin-like protein Syntaxin-6_N PF09177.9 NONMMLT007388.1_29611102_2 - 0.099 13.1 8.2 0.15 12.5 8.2 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal IncA PF04156.12 NONMMLT007388.1_29611102_2 - 0.12 12.0 23.5 0.12 12.1 21.1 1.8 1 1 1 2 2 2 0 IncA protein Jnk-SapK_ap_N PF09744.7 NONMMLT007388.1_29611102_2 - 0.13 12.4 20.3 0.2 11.8 20.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Prefoldin_2 PF01920.18 NONMMLT007388.1_29611102_2 - 0.16 11.9 15.7 0.041 13.7 4.4 2.7 1 1 2 3 3 3 0 Prefoldin subunit Laminin_II PF06009.10 NONMMLT007388.1_29611102_2 - 0.17 11.8 6.2 0.27 11.1 5.9 1.5 1 1 0 1 1 1 0 Laminin Domain II Syntaxin_2 PF14523.4 NONMMLT007388.1_29611102_2 - 0.18 12.1 9.8 0.29 11.4 9.8 1.4 1 0 0 1 1 1 0 Syntaxin-like protein Fez1 PF06818.13 NONMMLT007388.1_29611102_2 - 0.18 12.1 20.7 3.7 7.8 20.6 1.9 1 1 0 1 1 1 0 Fez1 DUF2408 PF10303.7 NONMMLT007388.1_29611102_2 - 0.22 11.9 10.3 0.28 11.6 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Golgin_A5 PF09787.7 NONMMLT007388.1_29611102_2 - 0.23 10.8 20.4 0.32 10.3 20.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fib_alpha PF08702.8 NONMMLT007388.1_29611102_2 - 0.26 11.3 10.2 0.34 11.0 10.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.10 NONMMLT007388.1_29611102_2 - 0.3 10.3 16.7 0.36 10.0 16.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.12 NONMMLT007388.1_29611102_2 - 0.34 10.6 13.4 0.43 10.2 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PI3K_P85_iSH2 PF16454.3 NONMMLT007388.1_29611102_2 - 0.34 10.3 18.4 0.28 10.6 10.4 1.9 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3450 PF11932.6 NONMMLT007388.1_29611102_2 - 0.45 9.6 15.9 0.39 9.9 14.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3584 PF12128.6 NONMMLT007388.1_29611102_2 - 0.45 7.8 18.4 0.5 7.7 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4795 PF16043.3 NONMMLT007388.1_29611102_2 - 0.46 9.9 14.2 0.45 9.9 6.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Spc7 PF08317.9 NONMMLT007388.1_29611102_2 - 0.48 9.1 17.3 0.77 8.4 17.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.11 NONMMLT007388.1_29611102_2 - 0.59 10.4 6.2 0.35 11.2 1.5 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF4407 PF14362.4 NONMMLT007388.1_29611102_2 - 0.62 9.2 11.0 0.38 9.9 8.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.10 NONMMLT007388.1_29611102_2 - 0.75 9.7 9.4 0.6 10.0 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.11 NONMMLT007388.1_29611102_2 - 0.76 9.4 13.0 1.7 8.3 12.6 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMPIT PF07851.11 NONMMLT007388.1_29611102_2 - 0.84 8.7 11.3 1 8.4 11.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Allexi_40kDa PF05549.9 NONMMLT007388.1_29611102_2 - 1.1 8.6 7.7 1.3 8.4 7.7 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Mnd1 PF03962.13 NONMMLT007388.1_29611102_2 - 1.2 8.8 21.5 7.1 6.3 21.5 1.8 1 1 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.17 NONMMLT007388.1_29611102_2 - 1.3 6.6 9.9 1.6 6.4 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.11 NONMMLT007388.1_29611102_2 - 1.3 9.6 11.0 2.5 8.7 4.8 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF812 PF05667.9 NONMMLT007388.1_29611102_2 - 1.4 7.6 19.3 3.8 6.1 19.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) SlyX PF04102.10 NONMMLT007388.1_29611102_2 - 1.4 9.4 15.8 1.4 9.5 4.6 2.7 1 1 2 3 3 3 0 SlyX SKA1 PF07160.10 NONMMLT007388.1_29611102_2 - 1.5 8.5 12.9 1.9 8.1 5.7 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 ATG16 PF08614.9 NONMMLT007388.1_29611102_2 - 1.8 8.6 22.2 4.3 7.3 22.2 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3510 PF12022.6 NONMMLT007388.1_29611102_2 - 1.8 8.8 8.6 13 6.0 8.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) DUF972 PF06156.11 NONMMLT007388.1_29611102_2 - 2.2 8.8 11.9 0.83 10.2 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HAUS6_N PF14661.4 NONMMLT007388.1_29611102_2 - 2.2 7.7 12.3 2.6 7.5 12.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Neur_chan_memb PF02932.14 NONMMLT007388.1_29611102_2 - 2.3 8.1 4.5 2.5 8.0 4.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region KELK PF15796.3 NONMMLT007388.1_29611102_2 - 3.3 8.1 22.3 0.23 11.9 9.6 2.1 1 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tho2 PF11262.6 NONMMLT007388.1_29611102_2 - 3.4 6.6 14.2 20 4.1 14.2 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.13 NONMMLT007388.1_29611102_2 - 3.6 6.9 14.9 4.3 6.7 14.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.14 NONMMLT007388.1_29611102_2 - 3.8 7.9 12.3 11 6.4 8.6 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 LMBR1 PF04791.14 NONMMLT007388.1_29611102_2 - 4 6.1 7.7 4.8 5.8 7.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.7 NONMMLT007388.1_29611102_2 - 4.6 6.1 18.9 5.7 5.8 18.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.10 NONMMLT007388.1_29611102_2 - 5.2 5.4 9.5 6.4 5.1 9.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4763 PF15960.3 NONMMLT007388.1_29611102_2 - 5.6 6.0 21.7 31 3.6 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Macoilin PF09726.7 NONMMLT007388.1_29611102_2 - 5.9 5.2 20.4 25 3.1 18.7 1.9 1 1 1 2 2 2 0 Transmembrane protein Swi5 PF07061.9 NONMMLT007388.1_29611102_2 - 6.1 6.8 10.7 0.86 9.6 3.5 2.4 1 1 1 2 2 2 0 Swi5 Spc24 PF08286.9 NONMMLT007388.1_29611102_2 - 7.5 6.7 16.5 5.4 7.2 7.7 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.10 NONMMLT007388.1_29611102_2 - 7.6 6.9 22.6 0.1 12.9 9.0 2.8 1 1 1 3 3 2 0 Cell division protein ZapB DUF342 PF03961.11 NONMMLT007388.1_29611102_2 - 7.8 4.8 10.6 9.8 4.5 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlaC_arch PF05377.9 NONMMLT007388.1_29611102_2 - 7.9 6.8 7.1 4.9 7.5 0.1 2.7 2 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.11 NONMMLT007388.1_29611102_2 - 8.2 5.8 13.8 39 3.6 13.8 1.9 1 1 0 1 1 1 0 fzo-like conserved region FYVE PF01363.19 NONMMLT007390.1_29613102_1 - 1.1e-19 70.2 10.4 1.1e-19 70.2 10.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_5 PF14634.4 NONMMLT007390.1_29613102_1 - 0.0011 18.8 15.1 0.004 16.9 15.1 2.1 1 0 0 1 1 1 1 zinc-RING finger domain FYVE_2 PF02318.14 NONMMLT007390.1_29613102_1 - 0.0066 16.5 6.9 0.018 15.1 6.9 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger HypA PF01155.17 NONMMLT007390.1_29613102_1 - 0.017 15.0 3.3 0.045 13.6 3.3 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.5 NONMMLT007390.1_29613102_1 - 1.9 8.4 19.4 1.7 8.6 3.7 3.6 2 1 1 3 3 3 0 Double zinc ribbon ADK_lid PF05191.12 NONMMLT007390.1_29613102_1 - 9.6 6.2 9.9 5.4 7.0 6.9 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid BAGE PF08180.9 NONMMLT007394.1_29613102_2 - 0.0002 21.2 0.6 0.00035 20.5 0.6 1.4 1 0 0 1 1 1 1 B melanoma antigen family Hira PF07569.9 NONMMLT007400.1_29612102_3 - 0.13 11.8 0.8 0.18 11.4 0.8 1.1 1 0 0 1 1 1 0 TUP1-like enhancer of split ECSCR PF15820.3 NONMMLT007560.1_29611102_2 - 0.0079 15.9 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator DER1 PF04511.13 NONMMLT007596.1_29611102_1 - 0.021 14.4 0.1 0.022 14.3 0.1 1.0 1 0 0 1 1 1 0 Der1-like family PsbM PF05151.10 NONMMLT007600.1_29612102_1 - 0.051 13.3 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) Cys_rich_CWC PF14375.4 NONMMLT007602.1_29611102_2 - 0.032 14.5 1.2 0.051 13.9 1.2 1.3 1 0 0 1 1 1 0 Cysteine-rich CWC Cortexin PF11057.6 NONMMLT007710.1_29612118_3 - 8.9e-41 137.5 0.1 1.4e-40 136.9 0.1 1.3 1 0 0 1 1 1 1 Cortexin of kidney Cadherin_3 PF16184.3 NONMMLT007754.1_29611102_2 - 0.066 13.1 0.0 0.29 11.0 0.0 1.9 2 1 0 2 2 2 0 Cadherin-like Bombesin PF02044.15 NONMMLT007767.1_29612102_3 - 0.015 15.2 2.4 0.039 13.9 2.4 1.7 1 0 0 1 1 1 0 Bombesin-like peptide DUF3719 PF12516.6 NONMMLT007792.1_29614102_2 - 3.6e-16 58.5 2.5 2.3e-15 55.9 2.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3719) PRP38 PF03371.13 NONMMLT007839.1_29611104_2 - 0.03 14.1 0.3 0.041 13.6 0.3 1.3 1 1 0 1 1 1 0 PRP38 family Integrin_B_tail PF07965.10 NONMMLT007914.1_29612102_2 - 0.0038 17.6 0.0 0.0092 16.3 0.0 1.6 1 0 0 1 1 1 1 Integrin beta tail domain ENOD40 PF08247.9 NONMMLT007922.1_29617102_2 - 6.4 6.9 8.3 4.4 7.4 1.0 3.7 3 0 0 3 3 3 0 ENOD40 protein Peptidase_A22B PF04258.11 NONMMLT007983.1_29612102_3 - 4.1e-38 131.4 3.8 4.8e-38 131.2 3.8 1.0 1 0 0 1 1 1 1 Signal peptide peptidase Presenilin PF01080.15 NONMMLT007983.1_29612102_3 - 0.049 12.3 4.8 0.069 11.8 4.8 1.2 1 0 0 1 1 1 0 Presenilin DUF2418 PF10332.7 NONMMLT007991.1_29612102_1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) DUF2418 PF10332.7 NONMMLT007993.1_29612102_1 - 0.16 12.4 0.3 0.32 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) COX7C PF02935.14 NONMMLT008020.1_29612102_2 - 6.7e-21 74.2 0.2 1.3e-20 73.3 0.2 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc CD225 PF04505.10 NONMMLT008157.1_29611102_2 - 8.3e-10 38.5 0.1 1.3e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein TOBE PF03459.15 NONMMLT008168.1_29612102_2 - 0.065 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 TOBE domain DUF1725 PF08333.9 NONMMLT008198.1_29612102_1 - 3.4e-06 26.4 0.1 4.9e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) GETHR PF05671.9 NONMMLT008222.1_29612102_1 - 1.3 8.3 6.0 0.79 9.0 1.4 2.4 2 0 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) PDEase_I_N PF08499.10 NONMMLT008268.1_29613102_2 - 0.017 14.8 0.3 0.028 14.1 0.3 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal TNFR_c6 PF00020.16 NONMMLT008278.1_29612102_3 - 0.0025 18.0 7.3 0.0047 17.2 3.1 2.4 2 0 0 2 2 2 1 TNFR/NGFR cysteine-rich region IDO PF01231.16 NONMMLT008301.1_29612102_2 - 0.009 14.7 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1725 PF08333.9 NONMMLT008323.1_29612102_1 - 6.3e-06 25.6 0.3 1.1e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) DUF2489 PF10675.7 NONMMLT008323.1_29612102_1 - 0.01 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) zf-CCHC PF00098.21 NONMMLT008324.1_29616102_1 - 9.4e-10 38.0 11.3 6.3e-07 29.1 3.5 2.8 2 0 0 2 2 2 2 Zinc knuckle Gag_p30 PF02093.14 NONMMLT008324.1_29616102_1 - 8.7e-07 28.5 0.0 2.2e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Gag P30 core shell protein zf-CCHC_5 PF14787.4 NONMMLT008324.1_29616102_1 - 0.00014 21.3 11.5 0.0035 16.9 3.1 2.7 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger Gag_MA PF01140.17 NONMMLT008324.1_29616102_1 - 0.00027 20.5 0.0 0.00064 19.3 0.0 1.6 1 0 0 1 1 1 1 Matrix protein (MA), p15 zf-CCHC_3 PF13917.4 NONMMLT008324.1_29616102_1 - 0.00097 18.9 4.3 0.0058 16.4 1.3 2.6 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.4 NONMMLT008324.1_29616102_1 - 0.0023 17.5 1.7 1.9 8.1 0.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.4 NONMMLT008324.1_29616102_1 - 0.24 11.1 11.0 0.11 12.1 2.3 2.7 2 0 0 2 2 2 0 Zinc knuckle Gag_p30 PF02093.14 NONMMLT008324.1_29616102_2 - 1.8e-15 56.9 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Gag P30 core shell protein Ank_4 PF13637.4 NONMMLT008331.1_29612102_2 - 0.067 13.7 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) FAST_1 PF06743.13 NONMMLT008379.1_29612102_2 - 0.013 15.3 0.4 0.019 14.7 0.4 1.2 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 FAST_1 PF06743.13 NONMMLT008380.1_29612102_2 - 0.084 12.7 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 FAST_1 PF06743.13 NONMMLT008381.1_29612102_3 - 0.08 12.8 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 zf-C2H2 PF00096.24 NONMMLT008453.1_29613102_2 - 0.35 11.3 2.6 0.41 11.1 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type KRAB PF01352.25 NONMMLT008455.1_29613102_3 - 1e-19 69.8 0.0 1.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 KRAB box CD45 PF12567.6 NONMMLT008489.1_29612102_3 - 0.11 12.4 1.2 0.22 11.4 1.2 1.5 1 1 0 1 1 1 0 Leukocyte receptor CD45 LRR_8 PF13855.4 NONMMLT008511.1_29612102_1 - 6.8e-12 44.8 1.7 1.3e-11 43.9 1.7 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.5 NONMMLT008511.1_29612102_1 - 9.7e-06 25.7 2.3 0.0017 18.6 0.2 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 NONMMLT008511.1_29612102_1 - 0.0054 16.5 0.0 0.0084 15.9 0.0 1.2 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_9 PF14580.4 NONMMLT008511.1_29612102_1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.31 NONMMLT008511.1_29612102_1 - 0.46 11.0 2.7 11 6.9 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.4 NONMMLT008511.1_29612102_3 - 0.0069 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_8 PF13855.4 NONMMLT008512.1_29612102_2 - 0.0077 15.8 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_8 PF13855.4 NONMMLT008512.1_29612102_3 - 0.00052 19.6 0.2 0.0012 18.4 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat PSY3 PF16836.3 NONMMLT008516.1_29612102_3 - 0.02 14.3 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description DUF3558 PF12079.6 NONMMLT008600.1_29611102_3 - 0.043 13.7 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) MamL-1 PF09596.8 NONMMLT008651.1_29612102_1 - 0.05 13.7 0.8 0.076 13.1 0.8 1.2 1 0 0 1 1 1 0 MamL-1 domain YppG PF14179.4 NONMMLT008752.1_29613104_2 - 0.31 11.6 6.2 0.17 12.5 0.7 2.2 2 0 0 2 2 2 0 YppG-like protein PNRC PF15365.4 NONMMLT008799.1_29613102_2 - 0.053 14.0 0.7 0.053 14.0 0.7 1.7 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator DASH_Hsk3 PF08227.9 NONMMLT008803.1_29613104_3 - 0.29 11.4 1.8 0.34 11.2 0.2 1.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like RRP14 PF15459.4 NONMMLT008810.1_29612102_2 - 3 8.4 8.3 5.5 7.5 8.3 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 DDT PF02791.15 NONMMLT008973.1_29612102_1 - 0.08 13.1 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 DDT domain ADH_N PF08240.10 NONMMLT008974.1_29612102_2 - 0.013 15.2 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain zf-C3H1 PF10650.7 NONMMLT009040.1_29613102_3 - 0.054 13.1 0.2 0.096 12.3 0.2 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain Metallothio_6 PF05522.9 NONMMLT009063.1_29613102_1 - 0.03 14.7 1.1 0.03 14.7 1.1 2.1 2 0 0 2 2 2 0 Metallothionein Pkinase PF00069.23 NONMMLT009069.1_29611102_1 - 3.3e-12 46.2 0.1 3.8e-12 46.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 NONMMLT009069.1_29611102_1 - 4.6e-05 22.7 0.0 5.4e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Phospholip_A2_2 PF05826.10 NONMMLT009071.1_29611102_3 - 0.03 14.4 0.8 0.048 13.7 0.8 1.2 1 0 0 1 1 1 0 Phospholipase A2 Trypsin PF00089.24 NONMMLT009129.1_29611102_2 - 3.6e-13 49.7 0.0 4.3e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 NONMMLT009129.1_29611102_2 - 0.017 15.3 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) SHNi-TPR PF10516.7 NONMMLT009129.1_29611102_2 - 0.067 12.5 1.4 0.073 12.4 0.1 1.7 2 0 0 2 2 2 0 SHNi-TPR Trypsin PF00089.24 NONMMLT009129.1_29611102_3 - 1.6e-06 27.9 0.2 1.8e-06 27.8 0.2 1.1 1 0 0 1 1 1 1 Trypsin Acyl-CoA_dh_C PF12806.5 NONMMLT009136.1_29612102_3 - 0.074 13.1 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like DUF1725 PF08333.9 NONMMLT009200.1_29615102_3 - 0.12 11.9 0.9 0.22 11.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Carb_anhydrase PF00194.19 NONMMLT009206.1_29612102_1 - 9.8e-07 28.4 0.1 1.4e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.19 NONMMLT009206.1_29612102_3 - 1.8e-11 44.0 0.0 2.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Phage_tail_APC PF16778.3 NONMMLT009250.1_29614102_1 - 0.2 11.4 0.9 0.5 10.1 0.9 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Drf_FH1 PF06346.10 NONMMLT009252.1_29614102_1 - 1.2e-09 37.8 74.9 1e-06 28.4 20.7 4.4 4 2 0 4 4 4 3 Formin Homology Region 1 DUF1388 PF07142.10 NONMMLT009252.1_29614102_1 - 0.015 15.2 1.1 1.2 9.0 0.1 3.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) Drf_FH1 PF06346.10 NONMMLT009252.1_29614102_2 - 0.084 12.4 5.8 0.18 11.3 5.8 1.5 1 0 0 1 1 1 0 Formin Homology Region 1 DUF4072 PF13284.4 NONMMLT009280.1_29612102_1 - 9.8 6.6 6.4 13 6.1 5.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4072) FAM27 PF15832.3 NONDRET000438.2_16111104_1 - 0.0083 16.5 7.5 0.011 16.1 7.5 1.2 1 0 0 1 1 1 1 FAM27 D and E protein family PAN_4 PF14295.4 NONDRET000438.2_16111104_1 - 0.013 15.2 0.6 0.33 10.8 0.1 2.2 2 0 0 2 2 2 0 PAN domain CBFB_NFYA PF02045.13 NONDRET000438.2_16111104_2 - 0.12 13.0 1.3 0.12 13.0 1.3 1.8 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF2852 PF11014.6 NONDRET000550.2_16111102_1 - 0.055 13.5 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF4131 PF13567.4 NONDRET000565.2_16111102_2 - 0.0017 17.9 0.0 0.0021 17.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) UPF0086 PF01868.14 NONDRET000565.2_16111102_3 - 0.077 12.8 0.0 4.8 7.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function UPF0086 ATP_synth_reg PF14960.4 NONDRET000574.2_16112102_1 - 1.6e-16 59.4 0.1 2.6e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase regulation BTB PF00651.29 NONDRET000691.2_16111102_3 - 6.7e-15 55.1 0.2 8.4e-15 54.8 0.2 1.1 1 0 0 1 1 1 1 BTB/POZ domain Exo_endo_phos_2 PF14529.4 NONDRET000798.2_16112117_2 - 4.3e-07 29.7 0.3 5.5e-07 29.3 0.3 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.21 NONDRET000798.2_16112117_2 - 0.015 15.4 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family WAP PF00095.19 NONDRET000989.2_16112104_3 - 0.05 13.9 1.7 0.05 13.9 1.7 1.9 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' N2227 PF07942.10 NONDRET001030.2_16111102_1 - 0.077 12.0 0.1 0.096 11.7 0.1 1.1 1 0 0 1 1 1 0 N2227-like protein HOOK PF05622.10 NONDRET001031.2_16112102_2 - 0.0022 16.1 0.9 0.0027 15.8 0.9 1.0 1 0 0 1 1 1 1 HOOK protein Synaptobrevin PF00957.19 NONDRET001144.2_16111118_1 - 6.5e-13 48.2 0.9 9.3e-13 47.7 0.9 1.2 1 0 0 1 1 1 1 Synaptobrevin LOH1CR12 PF10158.7 NONDRET001144.2_16111118_1 - 0.067 13.1 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressor protein Pkinase PF00069.23 NONDRET001162.2_16113102_3 - 0.00012 21.4 0.2 0.0002 20.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain 5_nucleotid PF05761.12 NONDRET001284.2_16112102_1 - 1.1e-17 64.0 0.7 1.7e-17 63.4 0.7 1.2 1 0 0 1 1 1 1 5' nucleotidase family 5_nucleotid PF05761.12 NONDRET001284.2_16112102_2 - 2.4e-07 29.9 0.0 3.2e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family 5_nucleotid PF05761.12 NONDRET001284.2_16112102_3 - 1.1e-23 83.8 1.5 2.3e-23 82.7 0.1 1.8 2 0 0 2 2 2 1 5' nucleotidase family SET PF00856.26 NONDRET001297.2_16112102_2 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 SET domain Urease_beta PF00699.18 NONDRET001434.2_16111118_3 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Urease beta subunit CLN3 PF02487.15 NONDRET001482.2_16111102_1 - 0.042 12.8 0.2 0.05 12.5 0.2 1.0 1 0 0 1 1 1 0 CLN3 protein 7tm_1 PF00001.19 NONDRET001502.2_16111102_1 - 2.6e-08 33.3 2.0 3.4e-08 32.9 2.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-LITAF-like PF10601.7 NONDRET001502.2_16111102_1 - 0.027 14.6 1.7 0.032 14.4 1.0 1.5 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain 7tm_1 PF00001.19 NONDRET001506.2_16113102_2 - 1.9e-43 148.5 24.3 3e-43 147.8 24.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF212 PF02681.12 NONDRET001506.2_16113102_2 - 0.011 15.7 0.2 0.022 14.8 0.2 1.4 1 0 0 1 1 1 0 Divergent PAP2 family 7TM_GPCR_Srx PF10328.7 NONDRET001506.2_16113102_2 - 0.062 12.5 24.8 0.0088 15.2 19.1 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Tissue_fac PF01108.15 NONDRET001506.2_16113102_2 - 0.13 11.9 3.1 2.9 7.6 0.0 3.6 3 1 1 4 4 4 0 Tissue factor 7tm_1 PF00001.19 NONDRET001511.2_16111102_1 - 0.0055 15.9 0.2 0.0065 15.6 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) R3H PF01424.20 NONDRET001511.2_16111102_1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 R3H domain 7tm_1 PF00001.19 NONDRET001512.2_16111102_2 - 1.8e-06 27.3 0.5 2.3e-06 26.9 0.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.19 NONDRET001516.2_16113102_1 - 4.7e-40 137.4 28.8 4.7e-40 137.4 28.8 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 NONDRET001516.2_16113102_1 - 0.72 9.4 28.5 1.2 8.7 28.5 1.4 1 1 0 1 1 1 0 Olfactory receptor CBM_10 PF02013.14 NONDRET001520.2_16111104_1 - 0.041 14.2 0.6 0.08 13.3 0.6 1.5 1 0 0 1 1 1 0 Cellulose or protein binding domain FYVE PF01363.19 NONDRET001707.2_16112104_3 - 0.47 10.5 5.1 2.4 8.2 0.4 2.2 2 0 0 2 2 2 0 FYVE zinc finger PspB PF06667.10 NONDRET001835.2_16112117_1 - 1.9 8.5 5.1 3.2 7.8 5.1 1.3 1 0 0 1 1 1 0 Phage shock protein B DUF962 PF06127.9 NONDRET001912.2_16111102_2 - 1.3 9.0 4.8 14 5.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF962) PKcGMP_CC PF16808.3 NONDRET001930.2_16112102_2 - 8.4e-13 47.8 9.7 1.3e-12 47.2 9.7 1.3 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Wtap PF17098.3 NONDRET001930.2_16112102_2 - 0.0075 16.1 0.6 0.0097 15.7 0.6 1.1 1 0 0 1 1 1 1 WTAP/Mum2p family Phage_HK97_TLTM PF06120.9 NONDRET001930.2_16112102_2 - 0.012 14.6 0.2 0.014 14.5 0.2 1.1 1 0 0 1 1 1 0 Tail length tape measure protein TPD52 PF04201.13 NONDRET001930.2_16112102_2 - 0.017 14.6 3.4 0.034 13.6 3.4 1.4 1 0 0 1 1 1 0 Tumour protein D52 family LMSTEN PF07988.10 NONDRET001930.2_16112102_2 - 0.57 9.5 7.0 1 8.7 7.0 1.4 1 0 0 1 1 1 0 LMSTEN motif DUF1658 PF07871.9 NONDRET002023.2_16114102_3 - 0.41 10.5 2.6 0.99 9.3 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) Axin_b-cat_bind PF08833.8 NONDRET002153.2_16112102_1 - 0.0073 16.3 0.2 0.016 15.1 0.2 1.7 2 0 0 2 2 2 1 Axin beta-catenin binding domain ETAA1 PF15350.4 NONDRET002187.2_16111102_2 - 4.2e-05 21.9 1.1 5.9e-05 21.5 1.1 1.2 1 0 0 1 1 1 1 Ewing's tumour-associated antigen 1 homologue PDZ_2 PF13180.4 NONDRET002218.2_16113102_1 - 3.6e-06 27.1 0.0 6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.22 NONDRET002218.2_16113102_1 - 0.0023 18.1 0.1 0.0034 17.5 0.1 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Trypsin_2 PF13365.4 NONDRET002218.2_16113102_2 - 5.8e-12 46.6 0.1 7.4e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.24 NONDRET002218.2_16113102_2 - 3e-06 27.1 0.0 4.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.7 NONDRET002218.2_16113102_2 - 0.019 13.5 0.2 0.023 13.2 0.2 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.14 NONDRET002218.2_16113102_2 - 0.21 10.9 0.4 0.27 10.6 0.4 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) DUF4212 PF13937.4 NONDRET002265.2_16112102_1 - 0.039 14.2 0.5 0.058 13.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) TRC8_N PF13705.4 NONDRET002310.2_16112102_1 - 7.4e-15 54.7 0.2 8.3e-15 54.5 0.2 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain Chromate_transp PF02417.13 NONDRET002310.2_16112102_1 - 0.073 13.1 0.1 0.097 12.7 0.1 1.1 1 0 0 1 1 1 0 Chromate transporter DUF1736 PF08409.9 NONDRET002310.2_16112102_1 - 0.097 12.6 1.8 0.099 12.5 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1736) SET PF00856.26 NONDRET002324.2_16112117_3 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 SET domain B_lectin PF01453.22 NONDRET002597.2_16111102_3 - 0.051 13.5 0.1 0.071 13.0 0.1 1.3 1 1 0 1 1 1 0 D-mannose binding lectin DUF2418 PF10332.7 NONDRET002601.2_16112104_2 - 0.12 12.8 0.1 0.18 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) LSR PF05624.12 NONDRET002603.2_16112102_2 - 0.00096 19.0 2.6 0.00096 19.0 2.6 2.5 2 0 0 2 2 2 1 Lipolysis stimulated receptor (LSR) Cadherin_C_2 PF16492.3 NONDRET002603.2_16112102_2 - 0.015 15.9 0.1 0.033 14.8 0.0 1.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF1689 PF07954.9 NONDRET002786.2_16112102_2 - 0.063 13.6 0.1 0.095 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) zf-C2H2 PF00096.24 NONDRET003229.2_16113102_1 - 4.7e-07 29.8 6.1 0.24 11.8 0.0 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET003229.2_16113102_1 - 6.4e-07 29.5 4.4 0.45 11.4 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zinc_ribbon_10 PF10058.7 NONDRET003229.2_16113102_1 - 0.0019 17.7 2.9 8.2 6.1 0.1 3.3 3 0 0 3 3 3 2 Predicted integral membrane zinc-ribbon metal-binding protein C1_4 PF07975.10 NONDRET003229.2_16113102_1 - 0.002 18.2 4.6 0.0086 16.2 0.2 3.1 3 0 0 3 3 3 1 TFIIH C1-like domain E6 PF00518.15 NONDRET003229.2_16113102_1 - 0.91 9.9 4.7 0.92 9.9 2.1 2.0 1 1 1 2 2 2 0 Early Protein (E6) zf-C2H2_11 PF16622.3 NONDRET003229.2_16113102_1 - 2.6 7.8 5.1 3.3 7.4 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-UBP PF02148.17 NONDRET003229.2_16113102_1 - 9.9 6.5 7.2 75 3.6 3.4 2.9 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DUF1818 PF08848.9 NONDRET003276.2_16112102_2 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) Atrophin-1 PF03154.13 NONDRET003378.2_16112102_1 - 1.4 6.9 6.0 1.9 6.6 6.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DEK_C PF08766.9 NONDRET003584.2_16113102_2 - 7.3e-16 57.7 1.0 1.2e-15 57.1 1.0 1.3 1 0 0 1 1 1 1 DEK C terminal domain ATP1G1_PLM_MAT8 PF02038.14 NONDRET003623.2_16111118_3 - 2.5e-08 33.0 0.0 3.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family LMBR1 PF04791.14 NONDRET003643.2_16111102_2 - 0.17 10.6 0.6 0.19 10.4 0.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein RNA_pol_Rpc4 PF05132.12 NONDRET003643.2_16111102_2 - 8 6.8 14.3 10 6.4 14.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNA_pol_Rpc4 PF05132.12 NONDRET003643.2_16111102_3 - 0.0007 19.9 5.0 0.0007 19.9 5.0 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 DDHD PF02862.15 NONDRET003643.2_16111102_3 - 0.068 13.2 7.3 0.067 13.2 7.3 1.1 1 0 0 1 1 1 0 DDHD domain PgpA PF04608.11 NONDRET003742.2_16111102_3 - 0.022 14.7 0.1 0.025 14.5 0.1 1.0 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A Fer4_5 PF12801.5 NONDRET003976.2_16113102_3 - 0.014 15.2 0.2 0.029 14.2 0.2 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain SH3_5 PF08460.8 NONDRET004008.2_16111102_1 - 0.061 13.3 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain LCE PF14672.4 NONDRET004076.2_16114102_2 - 3.6 8.2 7.8 0.18 12.3 1.3 2.1 2 0 0 2 2 2 0 Late cornified envelope Tme5_EGF_like PF09064.8 NONDRET004127.2_16111102_1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like DUF4303 PF14136.4 NONDRET004275.2_16114102_3 - 0.06 13.0 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) C1-set_C PF16196.3 NONDRET004283.2_16112102_1 - 0.013 14.7 0.6 0.021 14.1 0.6 1.3 1 0 0 1 1 1 0 C1-set C-terminal domain MHC_II_alpha PF00993.18 NONDRET004283.2_16112102_3 - 3.4e-17 61.8 0.2 7.2e-17 60.7 0.2 1.6 1 1 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set PF07654.13 NONDRET004283.2_16112102_3 - 5.3e-15 55.5 0.1 1.3e-14 54.3 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 NONDRET004283.2_16112102_3 - 0.0033 17.9 0.0 0.0063 17.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain SET PF00856.26 NONDRET004314.2_16113102_3 - 6.1e-09 36.3 0.1 1.4e-08 35.2 0.0 1.6 2 0 0 2 2 2 1 SET domain DUF1541 PF07563.9 NONDRET004314.2_16113102_3 - 0.073 12.8 0.0 32 4.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) TIL PF01826.15 NONDRET004505.2_16112102_3 - 0.17 12.1 9.0 0.4 10.8 9.0 1.6 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain MAP7 PF05672.9 NONDRET004582.2_16112102_1 - 1.2e-15 57.4 14.3 2.3e-15 56.6 14.3 1.4 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family MAP7 PF05672.9 NONDRET004584.2_16113102_2 - 7.9e-21 74.3 15.5 1.1e-20 73.9 15.5 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family V-set PF07686.15 NONDRET004630.2_16111102_1 - 0.00088 19.3 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain V-set PF07686.15 NONDRET004635.2_16111102_1 - 1.5e-16 60.4 0.0 1.8e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 NONDRET004635.2_16111102_1 - 1.6e-07 31.2 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 NONDRET004635.2_16111102_1 - 8.5e-07 29.4 0.0 1.5e-06 28.6 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 NONDRET004635.2_16111102_1 - 0.00025 21.2 0.0 0.00051 20.2 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 NONDRET004635.2_16111102_1 - 0.00027 20.8 0.0 0.00046 20.1 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.15 NONDRET004636.2_16111102_1 - 3.2e-16 59.3 3.3 4.5e-16 58.8 3.3 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 NONDRET004636.2_16111102_1 - 8.7e-07 29.3 3.6 4.1e-06 27.2 3.6 1.9 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 NONDRET004636.2_16111102_1 - 1.8e-06 27.9 4.4 1.5e-05 25.0 4.4 2.2 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 NONDRET004636.2_16111102_1 - 9.9e-05 22.2 0.4 0.0004 20.3 0.3 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.4 NONDRET004636.2_16111102_1 - 0.19 12.0 7.7 1.1 9.6 7.1 2.1 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.15 NONDRET004638.2_16111102_2 - 2.6e-07 30.6 0.0 2.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 NONDRET004638.2_16111102_2 - 0.042 14.3 0.0 0.049 14.1 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.14 NONDRET004638.2_16111102_2 - 0.049 13.6 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.23 NONDRET004638.2_16111102_2 - 0.053 13.6 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.15 NONDRET004638.2_16111102_3 - 0.0077 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 NONDRET004638.2_16111102_3 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain C1-set PF07654.13 NONDRET004640.2_16111102_2 - 2.3e-09 37.4 0.1 2.6e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain V-set PF07686.15 NONDRET004641.2_16111102_1 - 2.3e-18 66.2 0.0 2.7e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 NONDRET004641.2_16111102_1 - 8.7e-08 32.1 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 NONDRET004641.2_16111102_1 - 3.5e-07 30.6 0.0 6.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 NONDRET004641.2_16111102_1 - 2.4e-05 24.2 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.4 NONDRET004641.2_16111102_1 - 4.5e-05 23.6 0.0 0.00011 22.3 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 NONDRET004643.2_16111102_1 - 0.0014 18.6 0.3 0.042 13.9 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.4 NONDRET004643.2_16111102_1 - 0.3 11.6 2.2 4.8 7.7 2.2 2.1 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.15 NONDRET004643.2_16111102_2 - 0.002 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain MACPF PF01823.17 NONDRET004657.2_16113102_1 - 1.3e-11 44.9 0.0 1.8e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 MAC/Perforin domain C2 PF00168.28 NONDRET004657.2_16113102_3 - 1.8e-10 40.9 0.1 4.6e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 C2 domain Gal_Lectin PF02140.16 NONDRET004705.2_16112102_2 - 6.6e-16 58.4 1.6 3.9e-07 30.3 0.2 2.4 2 0 0 2 2 2 2 Galactose binding lectin domain Gal_Lectin PF02140.16 NONDRET004705.2_16112102_3 - 0.0092 16.3 0.1 0.085 13.2 0.0 2.0 2 0 0 2 2 2 1 Galactose binding lectin domain mTERF PF02536.12 NONDRET004848.2_16112118_1 - 0.0031 16.4 0.0 0.0041 16.0 0.0 1.1 1 0 0 1 1 1 1 mTERF UCR_14kD PF02271.14 NONDRET004848.2_16112118_2 - 1.7e-30 104.8 0.5 2.8e-30 104.1 0.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF2967 PF11179.6 NONDRET004936.2_16112102_1 - 0.31 10.3 4.0 0.46 9.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF2967 PF11179.6 NONDRET004937.2_16112102_2 - 0.37 10.1 4.4 0.51 9.6 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF2887 PF11103.6 NONDRET005007.2_16111104_3 - 0.078 12.8 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) DUF4303 PF14136.4 NONDRET005019.2_16115102_1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) FAIM1 PF06905.11 NONDRET005161.2_16112104_2 - 0.11 12.0 0.2 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 Fas apoptotic inhibitory molecule (FAIM1) zf-rbx1 PF12678.5 NONDRET005241.2_16111102_2 - 0.053 13.7 1.8 0.053 13.7 1.8 1.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain UPF0560 PF10577.7 NONDRET005268.2_16112102_2 - 1.4 7.2 6.4 1.8 6.8 6.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Tachystatin_B PF11478.6 NONDRET005287.2_16112102_1 - 0.05 13.4 1.0 0.12 12.2 1.0 1.7 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B TMEM132D_C PF15706.3 NONDRET005403.2_16111102_3 - 0.033 13.8 0.4 0.044 13.4 0.4 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Pro-rich PF15240.4 NONDRET005404.2_16112102_2 - 2.3 8.4 42.2 86 3.3 42.2 2.0 1 1 0 1 1 1 0 Proline-rich Synaphin PF05835.10 NONDRET005413.2_16113102_1 - 0.15 12.2 0.7 0.3 11.3 0.7 1.4 1 0 0 1 1 1 0 Synaphin protein Ost4 PF10215.7 NONDRET005421.2_16112102_2 - 0.89 9.3 4.4 1.8 8.3 4.4 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase Ost4 PF10215.7 NONDRET005422.2_16112102_3 - 0.79 9.5 4.4 1.6 8.5 4.4 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase Ost4 PF10215.7 NONDRET005424.2_16112102_2 - 0.75 9.5 4.4 1.5 8.6 4.4 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase Neugrin PF06413.9 NONDRET005431.2_16112102_2 - 0.37 10.6 8.9 0.48 10.3 8.9 1.1 1 0 0 1 1 1 0 Neugrin DX PF01666.15 NONDRET005431.2_16112102_3 - 0.071 13.5 1.9 0.22 11.9 0.5 2.4 2 1 0 2 2 2 0 DX module PP2C PF00481.19 NONDRET005515.2_16111102_3 - 0.11 11.9 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C PDDEXK_2 PF12784.5 NONDRET005518.2_16111102_2 - 0.1 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase DUF997 PF06196.10 NONDRET005518.2_16111102_3 - 0.024 14.5 5.4 0.024 14.5 5.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF997) MVL PF12151.6 NONDRET005609.2_16112102_1 - 0.018 14.8 0.6 0.032 13.9 0.6 1.4 1 0 0 1 1 1 0 Mannan-binding protein Cadherin_pro PF08758.9 NONDRET005657.2_16112118_1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like p450 PF00067.20 NONDRET005740.2_16113102_2 - 6e-28 97.7 0.0 1.9e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 zf-4CXXC_R1 PF10497.7 NONDRET005848.2_16113102_1 - 0.039 14.1 3.2 0.073 13.2 3.2 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Ferritin PF00210.22 NONDRET005889.2_16112102_2 - 0.082 12.7 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Ferritin-like domain Ferritin PF00210.22 NONDRET005890.2_16112102_2 - 0.11 12.3 0.2 0.16 11.7 0.2 1.1 1 0 0 1 1 1 0 Ferritin-like domain FKBP_C PF00254.26 NONDRET005906.2_16112118_3 - 3.1e-27 94.6 0.0 4.1e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PSII PF00421.17 NONDRET005936.2_16111102_2 - 0.12 10.8 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Photosystem II protein DUF2635 PF10948.6 NONDRET005958.2_16112104_2 - 0.071 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) 7tm_4 PF13853.4 NONDRET006198.2_16112102_1 - 2.7e-18 66.6 13.3 3.5e-18 66.2 13.3 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 NONDRET006198.2_16112102_1 - 1.1e-16 60.8 14.7 1.3e-16 60.5 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GET2 PF08690.8 NONDRET006198.2_16112102_1 - 0.13 11.8 1.4 0.18 11.3 1.4 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 BCLP PF12304.6 NONDRET006316.2_16111104_2 - 0.033 13.6 4.3 0.053 12.9 4.3 1.3 1 0 0 1 1 1 0 Beta-casein like protein zf-H2C2_2 PF13465.4 NONDRET006434.2_16113118_2 - 3.4e-61 201.0 79.0 5.1e-10 39.2 0.4 10.7 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET006434.2_16113118_2 - 1e-45 151.5 97.7 2.5e-07 30.6 3.4 9.8 10 0 0 10 10 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET006434.2_16113118_2 - 1.8e-30 102.8 87.3 0.00021 21.7 2.5 10.0 10 0 0 10 10 9 9 C2H2-type zinc finger zf-C2H2_11 PF16622.3 NONDRET006434.2_16113118_2 - 4e-11 42.3 70.1 0.0063 16.1 4.6 9.3 9 0 0 9 9 9 6 zinc-finger C2H2-type zf-C2H2_jaz PF12171.6 NONDRET006434.2_16113118_2 - 8.5e-10 38.6 49.6 0.37 11.0 2.8 9.5 9 0 0 9 9 9 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 NONDRET006434.2_16113118_2 - 5e-09 35.8 79.1 0.064 13.1 2.2 10.5 10 1 0 10 10 10 7 C2H2-type zinc finger zf-LYAR PF08790.9 NONDRET006434.2_16113118_2 - 3.4e-06 26.7 50.9 0.018 14.8 1.6 9.0 9 0 0 9 9 9 4 LYAR-type C2HC zinc finger zf-met PF12874.5 NONDRET006434.2_16113118_2 - 1.4e-05 25.2 74.2 0.025 14.8 4.4 9.9 9 1 1 10 10 10 4 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.8 NONDRET006434.2_16113118_2 - 1.7e-05 24.7 36.0 0.5 10.4 0.1 7.4 4 2 5 9 9 9 6 Zinc ribbon domain E7 PF00527.16 NONDRET006434.2_16113118_2 - 0.03 14.4 0.7 0.22 11.6 0.7 2.5 1 0 0 1 1 1 0 E7 protein, Early protein ADK_lid PF05191.12 NONDRET006434.2_16113118_2 - 0.06 13.2 34.4 0.17 11.8 0.4 6.0 5 2 0 5 5 5 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.3 NONDRET006434.2_16113118_2 - 0.39 11.3 36.5 1.4 9.6 1.2 5.7 1 1 3 6 6 6 0 zinc-ribbon family zf-trcl PF13451.4 NONDRET006434.2_16113118_2 - 0.82 9.5 38.0 2.1 8.2 0.1 8.8 8 1 0 8 8 8 0 Probable zinc-ribbon domain DUF3268 PF11672.6 NONDRET006434.2_16113118_2 - 1.6 9.0 22.0 0.31 11.3 0.3 4.5 3 2 0 4 4 4 0 zinc-finger-containing domain zf-C2HC_2 PF13913.4 NONDRET006434.2_16113118_2 - 1.8 8.4 51.0 0.42 10.5 0.3 9.2 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.5 NONDRET006434.2_16113118_2 - 1.9 8.8 56.5 0.35 11.1 1.9 8.6 2 1 5 8 8 8 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.16 NONDRET006434.2_16113118_2 - 3.3 7.7 37.1 11 6.1 0.3 9.1 9 0 0 9 9 9 0 XPA protein N-terminal zf-H2C2_2 PF13465.4 NONDRET006446.2_16111102_2 - 6.2e-14 51.6 11.4 4.9e-10 39.3 0.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET006446.2_16111102_2 - 1.5e-12 47.1 7.6 3.6e-06 27.0 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET006446.2_16111102_2 - 3.5e-10 39.7 6.8 0.00021 21.7 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.4 NONDRET006446.2_16111102_2 - 3.7e-05 23.4 13.7 0.0051 16.6 0.9 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 NONDRET006446.2_16111102_2 - 6.4e-05 23.0 1.2 0.25 11.6 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding LIM PF00412.20 NONDRET006446.2_16111102_2 - 0.0017 18.4 6.2 0.022 14.9 1.0 2.4 2 0 0 2 2 2 1 LIM domain zf-C2H2_11 PF16622.3 NONDRET006446.2_16111102_2 - 0.0018 17.9 12.1 0.016 14.8 4.9 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type DZR PF12773.5 NONDRET006446.2_16111102_2 - 0.0032 17.3 3.2 0.0067 16.3 3.2 1.7 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.3 NONDRET006446.2_16111102_2 - 0.004 17.7 2.0 0.004 17.7 2.0 1.6 1 1 0 1 1 1 1 zinc-ribbon family zf-RING_7 PF02591.13 NONDRET006446.2_16111102_2 - 0.0071 16.4 1.8 4.4 7.4 0.2 2.9 3 0 0 3 3 3 2 C4-type zinc ribbon domain zf-LYAR PF08790.9 NONDRET006446.2_16111102_2 - 0.014 15.1 10.3 0.03 14.1 0.5 3.1 3 0 0 3 3 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.4 NONDRET006446.2_16111102_2 - 0.019 14.6 1.5 0.019 14.6 1.5 3.1 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HE PF16278.3 NONDRET006446.2_16111102_2 - 0.023 15.0 10.9 0.13 12.6 0.5 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.5 NONDRET006446.2_16111102_2 - 0.055 13.7 6.9 0.67 10.3 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.5 NONDRET006446.2_16111102_2 - 0.13 12.4 9.5 0.52 10.5 2.0 2.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.8 NONDRET006446.2_16111102_2 - 0.17 11.9 5.9 0.93 9.5 0.5 2.6 1 1 2 3 3 3 0 Zinc ribbon domain HypA PF01155.17 NONDRET006446.2_16111102_2 - 0.17 11.8 3.6 0.22 11.4 2.8 1.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-FCS PF06467.12 NONDRET006446.2_16111102_2 - 0.23 11.3 7.0 1.5 8.7 0.8 2.5 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-CHY PF05495.10 NONDRET006446.2_16111102_2 - 0.64 10.5 9.9 0.79 10.2 4.3 2.3 1 1 1 2 2 2 0 CHY zinc finger FYDLN_acid PF09538.8 NONDRET006446.2_16111102_2 - 5.6 7.6 16.5 1.5 9.4 0.5 2.8 1 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-H2C2_2 PF13465.4 NONDRET006447.2_16111102_1 - 2.1e-19 68.9 17.8 1.9e-09 37.4 0.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET006447.2_16111102_1 - 4.6e-11 42.4 21.4 6.3e-08 32.5 1.0 4.1 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET006447.2_16111102_1 - 8.7e-10 38.5 18.4 6.5e-05 23.3 0.7 3.8 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.4 NONDRET006447.2_16111102_1 - 5.1e-06 26.2 13.5 0.012 15.4 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-LYAR PF08790.9 NONDRET006447.2_16111102_1 - 2.1e-05 24.2 9.7 0.058 13.2 0.1 3.4 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.6 NONDRET006447.2_16111102_1 - 0.00043 20.4 4.7 0.6 10.4 0.0 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.6 NONDRET006447.2_16111102_1 - 0.0027 17.9 3.8 0.054 13.7 0.6 2.2 2 0 0 2 2 2 1 zinc-finger-containing domain zf-RING_7 PF02591.13 NONDRET006447.2_16111102_1 - 0.0039 17.2 2.5 3.7 7.7 0.0 3.5 3 0 0 3 3 3 1 C4-type zinc ribbon domain XPA_N PF01286.16 NONDRET006447.2_16111102_1 - 0.0056 16.6 7.0 3.7 7.5 0.1 3.4 3 0 0 3 3 3 2 XPA protein N-terminal LIM PF00412.20 NONDRET006447.2_16111102_1 - 0.015 15.4 13.2 0.098 12.8 1.7 3.2 2 1 0 2 2 2 0 LIM domain GAGA PF09237.9 NONDRET006447.2_16111102_1 - 0.034 13.8 1.8 0.081 12.6 0.1 2.2 1 1 1 2 2 2 0 GAGA factor zf-C2HE PF16278.3 NONDRET006447.2_16111102_1 - 0.036 14.4 0.2 0.036 14.4 0.2 3.4 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.8 NONDRET006447.2_16111102_1 - 0.049 13.6 12.1 8.5 6.5 12.0 2.9 1 1 1 2 2 2 0 Zinc ribbon domain DZR PF12773.5 NONDRET006447.2_16111102_1 - 0.061 13.2 12.0 2.2 8.2 12.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-met PF12874.5 NONDRET006447.2_16111102_1 - 0.15 12.4 15.0 1.6 9.1 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DNA_RNApol_7kD PF03604.11 NONDRET006447.2_16111102_1 - 0.17 11.4 10.5 4.1 7.0 0.1 3.4 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-trcl PF13451.4 NONDRET006447.2_16111102_1 - 0.19 11.5 10.8 2.4 8.0 0.1 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain TFIIS_C PF01096.16 NONDRET006447.2_16111102_1 - 0.2 11.4 14.4 1.8 8.4 0.4 3.3 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) C1_1 PF00130.20 NONDRET006447.2_16111102_1 - 0.45 10.3 13.1 0.41 10.4 3.5 3.1 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-AN1 PF01428.14 NONDRET006447.2_16111102_1 - 0.64 10.1 12.6 5.6 7.1 0.1 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger YhfH PF14149.4 NONDRET006447.2_16111102_1 - 1.2 9.0 11.3 3.2 7.7 0.1 3.3 3 0 0 3 3 3 0 YhfH-like protein SprT-like PF10263.7 NONDRET006447.2_16111102_1 - 1.5 8.5 10.0 2.4 7.8 4.3 1.9 1 1 1 2 2 2 0 SprT-like family zinc-ribbons_6 PF07191.10 NONDRET006447.2_16111102_1 - 2.3 8.1 11.3 2.7e+02 1.5 11.3 2.8 1 1 0 1 1 1 0 zinc-ribbons ADK_lid PF05191.12 NONDRET006447.2_16111102_1 - 3 7.8 7.9 1.5 8.8 0.3 3.2 1 1 2 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.5 NONDRET006447.2_16111102_1 - 3.4 7.9 11.6 6.2 7.1 3.6 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) HypA PF01155.17 NONDRET006447.2_16111102_1 - 6.1 6.8 8.7 0.47 10.4 1.1 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.8 NONDRET006447.2_16111102_1 - 7.2 7.2 5.9 9.9 6.8 1.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2H2_11 PF16622.3 NONDRET006447.2_16111102_1 - 7.3 6.3 16.6 0.28 10.8 1.0 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.4 NONDRET006448.2_16116102_2 - 2.2e-05 24.6 4.4 9.2e-05 22.6 1.9 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET006448.2_16116102_2 - 0.0052 17.1 3.8 0.0071 16.6 0.7 3.0 1 1 1 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 NONDRET006448.2_16116102_2 - 0.012 15.5 1.2 0.026 14.3 1.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.4 NONDRET006448.2_16116102_2 - 0.042 14.6 1.6 0.25 12.1 1.6 2.5 1 0 0 1 1 1 0 C2H2-type zinc finger Ig_2 PF13895.4 NONDRET006473.2_16111102_3 - 0.00055 20.1 3.3 0.00099 19.3 3.3 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 NONDRET006473.2_16111102_3 - 0.0036 17.2 0.1 0.0054 16.6 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 NONDRET006473.2_16111102_3 - 0.015 15.8 2.1 0.026 15.0 2.1 1.4 1 0 0 1 1 1 0 Immunoglobulin domain A2M PF00207.20 NONDRET006473.2_16111102_3 - 0.063 13.0 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family Collectrin PF16959.3 NONDRET006473.2_16111102_3 - 0.078 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Renal amino acid transporter DC_STAMP PF07782.11 NONDRET006473.2_16111102_3 - 0.27 10.9 1.9 0.32 10.7 1.9 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein Ig_3 PF13927.4 NONDRET006552.2_16116102_3 - 3.3e-10 40.3 2.0 0.0003 21.2 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 NONDRET006552.2_16116102_3 - 6.7e-07 29.3 0.5 7.7e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.14 NONDRET006552.2_16116102_3 - 2.1e-06 27.6 0.1 0.08 12.9 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.4 NONDRET006552.2_16116102_3 - 0.021 15.0 1.2 0.021 15.0 1.2 3.1 3 1 0 3 3 3 0 Immunoglobulin domain GAPT PF11770.6 NONDRET006552.2_16116102_3 - 0.074 12.8 0.3 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) ig PF00047.23 NONDRET006552.2_16116102_3 - 1.8 8.6 7.1 4 7.5 0.1 2.8 3 0 0 3 3 3 0 Immunoglobulin domain zf-H2C2_2 PF13465.4 NONDRET006553.2_16112102_2 - 2.8e-30 103.3 29.5 6.9e-09 35.6 2.0 5.2 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET006553.2_16112102_2 - 2.7e-21 74.6 38.4 2.9e-06 27.3 1.3 4.8 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET006553.2_16112102_2 - 4.7e-17 61.1 33.1 6e-05 23.4 0.6 4.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.3 NONDRET006553.2_16112102_2 - 6.7e-12 44.8 19.7 0.0017 17.9 0.3 5.0 5 0 0 5 5 5 4 zinc-finger C2H2-type zf-RING_7 PF02591.13 NONDRET006553.2_16112102_2 - 4.3e-09 36.3 12.3 0.013 15.6 0.1 5.2 5 0 0 5 5 5 3 C4-type zinc ribbon domain zf-C2H2_6 PF13912.4 NONDRET006553.2_16112102_2 - 5.6e-09 35.6 28.4 0.00036 20.3 0.6 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_5 PF13909.4 NONDRET006553.2_16112102_2 - 1.1e-05 24.9 44.0 0.027 14.1 2.2 6.4 5 2 0 5 5 5 4 C2H2-type zinc-finger domain ADK_lid PF05191.12 NONDRET006553.2_16112102_2 - 0.00014 21.7 12.3 0.0016 18.3 0.1 3.7 2 1 2 4 4 4 2 Adenylate kinase, active site lid zf-met PF12874.5 NONDRET006553.2_16112102_2 - 0.00074 19.7 23.0 0.071 13.4 1.7 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.4 NONDRET006553.2_16112102_2 - 0.00086 19.0 12.2 0.38 10.6 0.1 4.1 4 0 0 4 4 3 2 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.3 NONDRET006553.2_16112102_2 - 0.0012 19.0 8.3 0.028 14.6 0.8 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon C1_1 PF00130.20 NONDRET006553.2_16112102_2 - 0.0013 18.4 22.4 0.18 11.6 2.9 4.5 1 1 3 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.6 NONDRET006553.2_16112102_2 - 0.0038 17.4 12.5 0.3 11.3 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.7 NONDRET006553.2_16112102_2 - 0.0043 17.0 11.7 2.3 8.3 0.6 4.2 4 0 0 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.9 NONDRET006553.2_16112102_2 - 0.0076 15.9 8.4 0.016 14.9 0.5 3.2 1 1 1 3 3 3 1 GAGA factor DZR PF12773.5 NONDRET006553.2_16112102_2 - 0.008 16.1 22.3 5.9e+02 0.5 22.3 3.2 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.3 NONDRET006553.2_16112102_2 - 0.0081 16.8 17.1 0.19 12.4 3.0 2.9 1 1 3 4 4 4 2 zinc-ribbon family Zn-ribbon_8 PF09723.8 NONDRET006553.2_16112102_2 - 0.027 14.5 1.4 0.027 14.5 1.4 3.6 2 2 2 4 4 4 0 Zinc ribbon domain HypA PF01155.17 NONDRET006553.2_16112102_2 - 0.027 14.4 12.9 1.1e+02 2.8 12.9 2.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.5 NONDRET006553.2_16112102_2 - 0.032 14.4 20.0 0.093 12.9 0.7 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) PknG_rubred PF16919.3 NONDRET006553.2_16112102_2 - 0.046 13.7 1.0 0.046 13.7 1.0 2.6 1 1 2 3 3 3 0 Protein kinase G rubredoxin domain zf-FCS PF06467.12 NONDRET006553.2_16112102_2 - 0.06 13.2 15.0 2.5 8.0 0.3 4.2 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-LYAR PF08790.9 NONDRET006553.2_16112102_2 - 0.078 12.8 23.6 0.73 9.7 0.5 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.3 NONDRET006553.2_16112102_2 - 0.17 12.2 25.8 0.15 12.4 3.5 4.4 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger GATA PF00320.25 NONDRET006553.2_16112102_2 - 0.19 11.3 9.5 16 5.1 0.3 4.2 3 1 0 3 3 3 0 GATA zinc finger zf-TRAF PF02176.16 NONDRET006553.2_16112102_2 - 0.2 12.2 19.5 1.9 9.1 2.1 3.6 1 1 3 4 4 4 0 TRAF-type zinc finger FYVE PF01363.19 NONDRET006553.2_16112102_2 - 1.4 8.9 20.5 16 5.6 13.9 3.1 1 1 1 2 2 2 0 FYVE zinc finger XPA_N PF01286.16 NONDRET006553.2_16112102_2 - 1.5 8.8 22.7 3.3 7.7 0.2 4.8 5 0 0 5 5 5 0 XPA protein N-terminal CpXC PF14353.4 NONDRET006553.2_16112102_2 - 1.8 8.5 19.3 0.97 9.3 0.2 4.1 1 1 3 4 4 4 0 CpXC protein DUF3268 PF11672.6 NONDRET006553.2_16112102_2 - 1.8 8.8 10.4 0.15 12.3 0.7 2.7 1 1 2 3 3 3 0 zinc-finger-containing domain zf-trcl PF13451.4 NONDRET006553.2_16112102_2 - 1.9 8.3 21.1 4.3 7.2 0.2 4.8 5 0 0 5 5 5 0 Probable zinc-ribbon domain zf-RRPl_C4 PF17026.3 NONDRET006553.2_16112102_2 - 3.1 7.8 11.4 0.48 10.4 3.5 2.3 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Lar_restr_allev PF14354.4 NONDRET006553.2_16112102_2 - 8.1 6.8 12.1 1.3e+02 2.9 0.1 3.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar DUF983 PF06170.10 NONDRET006553.2_16112102_2 - 8.9 6.7 12.6 49 4.3 0.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF983) YyzF PF14116.4 NONDRET006553.2_16112102_2 - 9.2 6.3 17.7 8.5 6.4 0.3 4.8 5 0 0 5 5 5 0 YyzF-like protein DUF4303 PF14136.4 NONDRET006554.2_16113102_1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) UPF0242 PF06785.9 NONDRET006563.2_16111102_1 - 0.034 12.7 0.0 0.043 12.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Ig_3 PF13927.4 NONDRET006566.2_16112102_1 - 1.1e-05 25.8 0.3 5.2e-05 23.6 0.3 1.8 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 NONDRET006566.2_16112102_1 - 0.00018 21.5 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.14 NONDRET006566.2_16112102_1 - 0.00027 20.8 0.2 0.0013 18.6 0.2 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.23 NONDRET006566.2_16112102_1 - 0.0018 18.3 0.2 0.5 10.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 NONDRET006566.2_16112102_1 - 0.013 15.7 0.2 0.094 12.9 0.2 2.0 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.15 NONDRET006568.2_16112102_2 - 1.8e-08 34.4 0.0 3.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 NONDRET006568.2_16112102_2 - 0.0057 17.1 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 NONDRET006568.2_16112102_2 - 0.015 15.5 0.0 0.059 13.6 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.14 NONDRET006568.2_16112102_2 - 0.1 12.6 0.0 0.56 10.2 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin I-set domain DUF1079 PF06435.9 NONDRET006598.2_16112102_1 - 0.55 10.4 2.3 0.52 10.4 0.9 1.7 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) DUF1079 PF06435.9 NONDRET006599.2_16111102_2 - 0.39 10.8 2.5 0.35 11.0 0.9 1.7 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) Crystall PF00030.17 NONDRET006612.2_16112102_1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin Trypsin PF00089.24 NONDRET006644.2_16112102_1 - 1e-07 31.8 0.0 1.4e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.24 NONDRET006644.2_16112102_2 - 0.00026 20.8 0.0 0.00034 20.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.24 NONDRET006644.2_16112102_3 - 1.3e-22 80.5 0.3 1.7e-22 80.2 0.3 1.1 1 0 0 1 1 1 1 Trypsin Sushi PF00084.18 NONDRET006683.2_16113102_2 - 2.5e-13 50.3 7.3 0.00017 22.0 0.0 4.2 4 0 0 4 4 4 3 Sushi repeat (SCR repeat) HRM PF02793.20 NONDRET006683.2_16113102_2 - 0.0015 18.7 6.2 0.083 13.1 0.2 2.4 2 0 0 2 2 2 2 Hormone receptor domain zinc_ribbon_2 PF13240.4 NONDRET006733.2_16112118_2 - 0.05 13.2 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Gal_Lectin PF02140.16 NONDRET006733.2_16112118_3 - 3.2e-24 85.0 3.1 5.8e-24 84.2 3.1 1.4 1 0 0 1 1 1 1 Galactose binding lectin domain ANF_receptor PF01094.26 NONDRET006783.2_16111118_1 - 7.1e-27 94.3 0.0 7.9e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Alpha_L_fucos PF01120.15 NONDRET006783.2_16111118_1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.0 1 0 0 1 1 1 0 Alpha-L-fucosidase zf-CDGSH PF09360.8 NONDRET006818.2_16112117_3 - 0.028 14.5 0.6 0.059 13.5 0.6 1.5 1 0 0 1 1 1 0 Iron-binding zinc finger CDGSH type LRRNT PF01462.16 NONDRET006883.2_16111102_3 - 2.6e-06 26.8 1.6 4.8e-06 26.0 1.6 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.4 NONDRET006883.2_16111102_3 - 0.00078 19.0 0.3 0.0012 18.5 0.3 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.5 NONDRET006883.2_16111102_3 - 0.098 13.0 0.3 0.22 11.8 0.3 1.6 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) MoCo_carrier PF12694.5 NONDRET006994.2_16112104_3 - 0.033 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative molybdenum carrier DUF4303 PF14136.4 NONDRET007003.2_16112102_2 - 0.11 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) GARP PF16731.3 NONDRET007021.2_16112117_2 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma TNFR_c6 PF00020.16 NONDRET007045.2_16112102_2 - 0.12 12.7 4.6 0.22 11.8 4.6 1.5 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region SET PF00856.26 NONDRET007073.2_16113102_1 - 2e-07 31.4 0.0 3.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 SET domain 4_1_CTD PF05902.11 NONDRET007073.2_16113102_1 - 0.14 12.3 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.3 NONDRET007247.2_16112104_3 - 4.4 6.9 7.9 0.61 9.6 2.2 2.4 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type SelP_N PF04592.12 NONDRET007302.2_16112102_1 - 9 5.5 10.7 12 5.0 10.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Atrophin-1 PF03154.13 NONDRET007302.2_16112102_2 - 3.1 5.8 11.5 4.1 5.4 11.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family PPI_Ypi1 PF07491.9 NONDRET007527.2_16114104_2 - 0.49 10.1 3.2 0.82 9.4 0.8 2.1 2 0 0 2 2 2 0 Protein phosphatase inhibitor LELP1 PF15042.4 NONDRET007596.2_16111102_2 - 0.023 15.0 1.3 0.027 14.8 1.3 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 EF-hand_6 PF13405.4 NONDRET007656.2_16112102_3 - 0.00022 20.8 3.5 0.14 12.0 0.9 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.30 NONDRET007656.2_16112102_3 - 0.0032 16.8 2.2 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 NONDRET007656.2_16112102_3 - 0.032 14.6 3.0 0.086 13.2 3.0 1.8 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.4 NONDRET007656.2_16112102_3 - 0.047 13.3 4.0 0.49 10.1 3.0 2.2 1 1 1 2 2 2 0 EF-hand domain pair GIT_CC PF16559.3 NONDRET007656.2_16112102_3 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Transposase_1 PF01359.16 NONDRET007775.2_16112102_1 - 0.012 15.4 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Transposase (partial DDE domain) DAP10 PF07213.9 NONDRET007824.2_16112104_1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 DAP10 membrane protein SEC-C PF02810.13 NONDRET007824.2_16112104_2 - 0.25 11.2 4.2 0.23 11.3 1.5 2.3 2 0 0 2 2 2 0 SEC-C motif Ornatin PF02088.13 NONDRET008093.2_16112104_1 - 4.5e-05 23.0 1.3 7.8e-05 22.2 1.3 1.3 1 0 0 1 1 1 1 Ornatin Ornatin PF02088.13 NONDRET008094.2_16112104_3 - 6.9e-05 22.4 1.3 0.00016 21.3 1.3 1.6 1 0 0 1 1 1 1 Ornatin TF_Zn_Ribbon PF08271.10 NONDRET008095.2_16112104_2 - 0.081 12.3 1.1 1.5 8.3 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Ornatin PF02088.13 NONDRET008095.2_16112104_3 - 7.2e-05 22.4 1.3 0.00013 21.5 1.3 1.4 1 0 0 1 1 1 1 Ornatin DUF3915 PF13054.4 NONDRET008119.2_16113104_1 - 0.05 13.5 10.6 0.082 12.8 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 NONDRET008119.2_16113104_1 - 0.11 10.6 19.0 0.15 10.2 19.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3824 PF12868.5 NONDRET008119.2_16113104_1 - 0.29 11.6 7.8 0.43 11.1 7.8 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3915 PF13054.4 NONDRET008119.2_16113104_2 - 0.1 12.4 11.4 0.19 11.6 11.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Auts2 PF15336.4 NONDRET008119.2_16113104_3 - 3 7.8 8.4 4.6 7.2 8.4 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Atrophin-1 PF03154.13 NONDRET008119.2_16113104_3 - 3.7 5.6 24.8 4.9 5.2 24.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Atrophin-1 PF03154.13 NONDRET008120.2_16113104_1 - 0.077 11.1 8.3 0.093 10.9 8.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 NONDRET008120.2_16113104_1 - 1 9.2 13.1 1.6 8.6 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3915 PF13054.4 NONDRET008120.2_16113104_2 - 0.0023 17.8 1.8 0.0039 17.0 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) FAM27 PF15832.3 NONDRET008120.2_16113104_2 - 0.003 17.9 5.3 0.0063 16.9 5.3 1.5 1 0 0 1 1 1 1 FAM27 D and E protein family Atrophin-1 PF03154.13 NONDRET008120.2_16113104_2 - 0.093 10.9 7.8 0.13 10.4 7.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family Ycf54 PF10674.7 NONDRET008120.2_16113104_2 - 0.15 12.2 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) BES1_N PF05687.11 NONDRET008120.2_16113104_2 - 3 8.1 6.7 5.2 7.3 6.7 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Atrophin-1 PF03154.13 NONDRET008120.2_16113104_3 - 0.62 8.1 9.1 0.88 7.6 9.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family FAM27 PF15832.3 NONDRET008120.2_16113104_3 - 0.98 9.9 16.9 0.18 12.2 7.9 2.4 2 0 0 2 2 2 0 FAM27 D and E protein family DUF3915 PF13054.4 NONDRET008120.2_16113104_3 - 1.1 9.1 10.8 0.12 12.3 5.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) V-set PF07686.15 NONDRET008189.2_16111102_3 - 0.00094 19.2 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set PF07686.15 NONDRET008190.2_16111102_1 - 2.6e-10 40.3 0.0 3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 NONDRET008190.2_16111102_1 - 0.02 15.4 0.2 0.049 14.1 0.2 1.7 1 1 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.4 NONDRET008190.2_16111102_1 - 0.021 15.0 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.15 NONDRET008193.2_16112102_1 - 0.0015 18.5 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set PF07686.15 NONDRET008193.2_16112102_2 - 0.0094 16.0 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set PF07686.15 NONDRET008196.2_16111102_1 - 2.8e-05 24.1 0.0 3.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 NONDRET008196.2_16111102_1 - 0.035 14.2 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.15 NONDRET008196.2_16111102_3 - 0.014 15.4 0.1 0.014 15.4 0.1 1.5 2 0 0 2 2 2 0 Immunoglobulin V-set domain Mpv17_PMP22 PF04117.10 NONDRET008239.2_16112102_1 - 3.2e-09 36.7 6.3 6.2e-09 35.8 6.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family TruD PF01142.16 NONDRET008527.2_16113102_2 - 0.0012 17.6 0.7 3 6.4 0.1 3.0 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Dimer_Tnp_hAT PF05699.12 NONDRET008809.2_16112102_1 - 9.2e-10 38.1 0.7 1.4e-09 37.5 0.7 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-H2C2_2 PF13465.4 NONDRET009105.2_16112102_1 - 2.9e-12 46.3 30.6 6.5e-07 29.4 2.4 5.4 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET009105.2_16112102_1 - 3.3e-07 30.3 11.3 5.5e-06 26.4 3.3 5.3 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET009105.2_16112102_1 - 4.5e-05 23.8 9.4 0.00077 20.0 2.7 5.7 6 0 0 6 6 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 NONDRET009105.2_16112102_1 - 0.00078 19.6 12.5 0.0082 16.3 0.5 3.8 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 NONDRET009105.2_16112102_1 - 0.0047 16.9 4.2 1.1 9.3 0.2 3.3 3 0 0 3 3 3 1 Zinc ribbon domain zf-C2H2_6 PF13912.4 NONDRET009105.2_16112102_1 - 0.01 15.6 2.3 0.01 15.6 2.3 5.0 6 1 0 6 6 5 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.4 NONDRET009105.2_16112102_1 - 0.029 14.7 7.0 0.69 10.3 2.5 2.7 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain CpXC PF14353.4 NONDRET009105.2_16112102_1 - 0.037 13.9 2.2 6.5 6.7 0.4 2.7 1 1 1 2 2 2 0 CpXC protein zinc_ribbon_5 PF13719.4 NONDRET009105.2_16112102_1 - 0.04 13.5 3.9 1.5 8.5 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain LIM PF00412.20 NONDRET009105.2_16112102_1 - 0.052 13.7 6.4 3.8 7.7 1.0 3.0 1 1 0 2 2 2 0 LIM domain zf-H2C2_5 PF13909.4 NONDRET009105.2_16112102_1 - 0.067 12.8 23.4 1.4 8.6 0.1 5.2 4 1 0 4 4 4 0 C2H2-type zinc-finger domain COX5B PF01215.17 NONDRET009105.2_16112102_1 - 0.16 11.5 0.1 0.16 11.5 0.1 2.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Vb YhfH PF14149.4 NONDRET009105.2_16112102_1 - 0.46 10.4 5.6 24 4.9 0.1 3.4 3 0 0 3 3 3 0 YhfH-like protein zf-LYAR PF08790.9 NONDRET009105.2_16112102_1 - 1 9.2 6.6 6.4 6.6 0.4 2.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DNA_RNApol_7kD PF03604.11 NONDRET009105.2_16112102_1 - 2.1 7.9 9.7 1.3 8.6 0.7 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.4 NONDRET009105.2_16112102_1 - 3.9 7.3 9.7 1.2 8.9 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.4 NONDRET009105.2_16112102_1 - 4.5 7.0 8.1 13 5.5 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.4 NONDRET009105.2_16112102_1 - 4.9 7.0 7.5 5 7.0 0.3 3.2 3 0 0 3 3 3 0 Nudix N-terminal zf-H2C2_2 PF13465.4 NONDRET009105.2_16112102_2 - 0.00013 22.2 0.1 0.00036 20.7 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET009105.2_16112102_2 - 0.018 15.4 0.3 0.058 13.7 0.3 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 NONDRET009105.2_16112102_3 - 5.4e-11 42.3 15.2 4.1e-05 23.7 0.6 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET009105.2_16112102_3 - 4.5e-06 26.7 0.5 4.5e-06 26.7 0.5 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET009105.2_16112102_3 - 0.00032 21.2 0.3 0.00032 21.2 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.4 NONDRET009105.2_16112102_3 - 0.0042 16.9 0.2 0.0042 16.9 0.2 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.4 NONDRET009146.2_16113102_3 - 1e-89 291.2 100.8 4.1e-10 39.5 0.2 13.4 15 0 0 15 15 14 12 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET009146.2_16113102_3 - 1.1e-65 214.5 100.5 1.3e-07 31.5 0.9 13.2 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET009146.2_16113102_3 - 1.9e-48 158.7 93.3 2.4e-05 24.6 0.6 13.1 13 0 0 13 13 13 11 C2H2-type zinc finger zf-C2H2_6 PF13912.4 NONDRET009146.2_16113102_3 - 1.1e-22 79.4 77.6 0.002 17.9 0.9 13.4 13 0 0 13 13 13 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 NONDRET009146.2_16113102_3 - 1.9e-19 69.3 55.9 0.00058 20.0 0.2 12.1 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 NONDRET009146.2_16113102_3 - 3.4e-11 43.0 50.5 0.00031 20.7 1.2 8.9 3 2 8 11 11 11 7 Zinc ribbon domain zf-LYAR PF08790.9 NONDRET009146.2_16113102_3 - 9.3e-11 41.3 68.9 0.024 14.4 0.4 13.1 13 0 0 13 13 13 5 LYAR-type C2HC zinc finger C1_1 PF00130.20 NONDRET009146.2_16113102_3 - 4.1e-09 36.1 48.6 0.14 12.0 3.9 9.2 3 3 4 8 8 8 6 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.5 NONDRET009146.2_16113102_3 - 4.8e-09 36.0 44.2 0.16 11.9 0.3 6.7 3 2 0 3 3 2 2 Double zinc ribbon zf-met PF12874.5 NONDRET009146.2_16113102_3 - 2.4e-08 33.9 83.5 0.011 15.9 1.6 12.6 13 0 0 13 13 13 5 Zinc-finger of C2H2 type HypA PF01155.17 NONDRET009146.2_16113102_3 - 1.4e-07 31.4 33.8 1.4 8.9 4.7 6.8 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_7 PF02591.13 NONDRET009146.2_16113102_3 - 1.8e-07 31.1 26.5 4.9 7.3 0.1 9.8 10 0 0 10 10 10 2 C4-type zinc ribbon domain CpXC PF14353.4 NONDRET009146.2_16113102_3 - 1.9e-06 27.8 45.3 0.15 11.9 0.2 10.2 3 2 4 9 9 9 3 CpXC protein zf-trcl PF13451.4 NONDRET009146.2_16113102_3 - 2.8e-06 27.0 49.0 3.2 7.6 0.6 10.5 9 2 0 9 9 9 3 Probable zinc-ribbon domain zf-AN1 PF01428.14 NONDRET009146.2_16113102_3 - 6e-06 26.2 57.8 4.6 7.4 0.2 11.4 9 1 2 11 11 11 1 AN1-like Zinc finger zinc_ribbon_15 PF17032.3 NONDRET009146.2_16113102_3 - 1.4e-05 25.7 41.3 0.085 13.5 1.6 6.4 1 1 6 8 8 8 2 zinc-ribbon family DUF3268 PF11672.6 NONDRET009146.2_16113102_3 - 5.2e-05 23.4 37.1 1.2 9.4 0.4 6.7 3 2 5 9 9 9 5 zinc-finger-containing domain zf-C2H2_2 PF12756.5 NONDRET009146.2_16113102_3 - 5.3e-05 23.4 60.5 0.31 11.3 0.5 10.9 2 2 10 12 12 12 3 C2H2 type zinc-finger (2 copies) XPA_N PF01286.16 NONDRET009146.2_16113102_3 - 0.0011 18.8 44.0 13 5.8 0.1 11.3 11 0 0 11 11 11 0 XPA protein N-terminal zf-C2H2_11 PF16622.3 NONDRET009146.2_16113102_3 - 0.0018 17.8 60.3 0.0076 15.8 0.1 11.5 12 0 0 12 12 12 3 zinc-finger C2H2-type zinc_ribbon_9 PF14369.4 NONDRET009146.2_16113102_3 - 0.0042 17.2 37.9 2 8.6 0.1 10.2 9 2 2 11 11 10 1 zinc-ribbon zf-H2C2_5 PF13909.4 NONDRET009146.2_16113102_3 - 0.022 14.4 0.1 0.022 14.4 0.1 17.3 15 6 0 15 15 15 0 C2H2-type zinc-finger domain zf-C2HE PF16278.3 NONDRET009146.2_16113102_3 - 0.031 14.6 68.1 0.16 12.3 1.2 11.0 5 5 6 11 11 11 0 C2HE / C2H2 / C2HC zinc-binding finger ADK_lid PF05191.12 NONDRET009146.2_16113102_3 - 0.064 13.2 43.3 3.1 7.8 1.6 9.1 3 2 7 10 10 10 0 Adenylate kinase, active site lid LIM PF00412.20 NONDRET009146.2_16113102_3 - 0.13 12.4 53.7 0.12 12.5 4.0 8.7 4 3 4 8 8 6 0 LIM domain C1_4 PF07975.10 NONDRET009146.2_16113102_3 - 0.49 10.6 54.5 2.1 8.6 3.6 8.5 4 3 5 9 9 9 0 TFIIH C1-like domain zf-C2HC_2 PF13913.4 NONDRET009146.2_16113102_3 - 0.93 9.3 0.1 0.93 9.3 0.1 11.3 13 1 0 13 13 12 0 zinc-finger of a C2HC-type AAA_14 PF13173.4 NONDRET009146.2_16113102_3 - 1.6 8.6 3.6 73 3.3 0.2 4.0 3 1 2 5 5 4 0 AAA domain TerY_C PF15616.4 NONDRET009146.2_16113102_3 - 2.5 8.1 28.4 0.2 11.7 1.2 5.1 2 2 3 5 5 5 0 TerY-C metal binding domain HTH_18 PF12833.5 NONDRET009146.2_16113102_3 - 4.3 7.5 5.4 23 5.2 0.1 3.6 3 1 1 4 4 3 0 Helix-turn-helix domain DUF2316 PF10078.7 NONDRET009264.2_16111102_1 - 0.27 11.4 1.4 0.65 10.2 1.4 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF3979 PF13141.4 NONDRET009480.2_16113102_3 - 0.1 12.8 0.1 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3979) UPF0560 PF10577.7 NONDRET009557.2_16112102_3 - 0.42 8.9 6.5 0.55 8.5 6.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 IKKbetaNEMObind PF12179.6 NONDRET009622.2_16113102_3 - 1.1 9.2 7.2 3.4 7.6 0.7 3.6 1 1 2 3 3 3 0 I-kappa-kinase-beta NEMO binding domain DUF912 PF06024.10 NONDRET009679.2_16112102_3 - 8.6 6.6 5.9 17 5.7 5.9 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) KASH_CCD PF14662.4 NONDRET009748.2_16112102_2 - 0.034 13.8 0.1 0.048 13.4 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SET PF00856.26 NONDRET009749.2_16112102_3 - 5.2e-08 33.3 0.0 7.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF1541 PF07563.9 NONDRET009749.2_16112102_3 - 0.054 13.2 0.1 67 3.3 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1541) 4_1_CTD PF05902.11 NONDRET009749.2_16112102_3 - 0.11 12.6 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Atrophin-1 PF03154.13 NONDRET009792.2_16112104_1 - 6 4.9 6.2 7.2 4.6 6.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 NONDRET009792.2_16112104_3 - 0.0064 16.3 2.8 0.0094 15.8 2.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 NONDRET009792.2_16112104_3 - 0.037 12.2 1.9 0.046 11.9 1.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family FAM27 PF15832.3 NONDRET009792.2_16112104_3 - 0.075 13.5 2.2 0.075 13.5 2.2 1.6 2 0 0 2 2 2 0 FAM27 D and E protein family Mit_proteolip PF08039.9 NONDRET009925.2_16112102_3 - 0.76 10.0 5.3 1.3 9.2 5.3 1.4 1 0 0 1 1 1 0 Mitochondrial proteolipid CLLAC PF15675.3 NONDRET009960.2_16112102_2 - 0.024 14.0 0.2 0.054 12.9 0.2 1.6 1 0 0 1 1 1 0 CLLAC-motif containing domain BESS PF02944.18 NONDRET009984.2_16111102_3 - 0.13 12.0 0.5 0.23 11.2 0.5 1.4 1 0 0 1 1 1 0 BESS motif WBP-1 PF11669.6 NONDRET009987.2_16112102_3 - 0.072 13.6 2.9 0.072 13.6 1.4 1.8 2 0 0 2 2 2 0 WW domain-binding protein 1 zf-UBP PF02148.17 NONDRET010093.2_16112102_3 - 0.2 11.9 2.3 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein Trypsin PF00089.24 NONDRET010173.2_16112118_1 - 1.3e-14 54.4 0.4 1.9e-14 53.9 0.4 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.4 NONDRET010173.2_16112118_1 - 0.00016 22.0 1.0 0.00026 21.3 1.0 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.9 NONDRET010173.2_16112118_1 - 0.035 14.4 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.24 NONDRET010173.2_16112118_2 - 1.5e-14 54.2 0.0 1.8e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Trypsin GCHY-1 PF02649.12 NONDRET010173.2_16112118_2 - 0.097 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 IL8 PF00048.18 NONDRET010190.2_16111104_3 - 0.037 14.1 0.2 0.056 13.5 0.2 1.3 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like MAP7 PF05672.9 NONDRET010442.2_16111102_1 - 1.9e-18 66.6 18.0 1.9e-18 66.6 18.0 1.3 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family NAD_binding_1 PF00175.19 NONDRET010442.2_16111102_1 - 0.12 12.9 0.8 0.17 12.4 0.8 1.2 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Synaptobrevin PF00957.19 NONDRET010442.2_16111102_1 - 0.34 10.6 2.0 0.4 10.4 0.3 1.9 1 1 1 2 2 2 0 Synaptobrevin AP-5_subunit_s1 PF15001.4 NONDRET010442.2_16111102_1 - 3 7.7 7.1 3.6 7.4 7.0 1.3 1 1 0 1 1 1 0 AP-5 complex subunit sigma-1 RtcR PF06956.9 NONDRET010505.2_16111102_3 - 0.099 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase DUF4303 PF14136.4 NONDRET010511.2_16116102_2 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) DUF4303 PF14136.4 NONDRET010512.2_16116102_2 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) DUF3880 PF12996.5 NONDRET010801.2_16111104_1 - 0.14 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) DDE_3 PF13358.4 NONDRET010828.2_16114102_3 - 0.00033 20.3 0.1 0.0006 19.5 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease 7tm_1 PF00001.19 NONDRET011086.2_16111118_3 - 8.9e-06 25.0 0.2 1.2e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V-set PF07686.15 NONDRET011149.2_16111102_1 - 1e-05 25.5 2.2 1.7e-05 24.8 2.2 1.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 NONDRET011149.2_16111102_1 - 0.00088 19.7 2.0 0.0022 18.5 2.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 NONDRET011149.2_16111102_1 - 0.0084 16.1 2.3 0.024 14.7 2.3 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 NONDRET011149.2_16111102_1 - 0.017 15.1 0.4 0.77 9.7 0.2 2.1 2 0 0 2 2 2 0 Immunoglobulin I-set domain SET PF00856.26 NONDRET011453.2_16113102_2 - 1.2e-06 28.9 0.0 1.8e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 SET domain DUF1541 PF07563.9 NONDRET011453.2_16113102_2 - 0.027 14.2 0.0 16 5.3 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1541) DUF1541 PF07563.9 NONDRET011454.2_16113102_2 - 0.19 11.5 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) DUF1543 PF07566.10 NONDRET011478.2_16113102_1 - 0.084 12.5 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) SET PF00856.26 NONDRET011539.2_16112102_1 - 9.9e-07 29.2 0.0 1.5e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 SET domain Presenilin PF01080.15 NONDRET011608.2_16113104_3 - 2.9 6.4 7.0 3.7 6.1 7.0 1.1 1 0 0 1 1 1 0 Presenilin Reeler PF02014.14 NONDRET011769.2_16114102_2 - 2.4e-18 67.0 0.1 4e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Reeler domain Raffinose_syn PF05691.10 NONDRET011769.2_16114102_2 - 0.081 10.6 0.0 0.11 10.1 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Lamp PF01299.15 NONDRET011769.2_16114102_2 - 1.5 8.2 26.6 2.3 7.5 26.6 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) GF_recep_IV PF14843.4 NONDRET011977.2_16112102_3 - 2.2e-06 27.4 8.5 2.2e-06 27.4 8.5 1.5 2 0 0 2 2 2 1 Growth factor receptor domain IV Furin-like PF00757.18 NONDRET011977.2_16112102_3 - 6.7e-05 22.7 8.9 6.7e-05 22.7 8.9 1.5 2 0 0 2 2 2 1 Furin-like cysteine rich region VSP PF03302.11 NONDRET011977.2_16112102_3 - 0.013 14.3 4.1 0.018 13.8 4.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein SET PF00856.26 NONDRET011979.2_16115117_1 - 0.024 14.9 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 SET domain Peptidase_C48 PF02902.17 NONDRET012022.2_16112102_1 - 0.002 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PLDc_N PF13396.4 NONDRET012091.2_16112102_3 - 0.87 9.4 4.2 0.59 10.0 1.1 2.3 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal BING4CT PF08149.9 NONDRET012170.2_16111118_3 - 4.3e-15 55.2 0.0 7.9e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 BING4CT (NUC141) domain OSTbeta PF15048.4 NONDRET012191.2_16111118_1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein UCH_N PF16674.3 NONDRET012191.2_16111118_3 - 3.8e-15 55.6 0.0 5.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 HGAL PF15666.3 NONDRET012264.2_16114102_2 - 0.11 12.5 0.5 0.58 10.1 0.5 2.0 1 1 0 1 1 1 0 Germinal center-associated lymphoma Tom7 PF08038.10 NONDRET012300.2_16114104_3 - 0.1 12.2 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 TOM7 family DUF2635 PF10948.6 NONDRET012474.2_16112102_2 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Pkinase PF00069.23 NONDRET012590.2_16112102_1 - 2.4e-12 46.6 0.3 3.6e-12 46.1 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 NONDRET012590.2_16112102_1 - 3.9e-05 22.9 0.1 7.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 NONDRET012590.2_16112102_1 - 0.00027 20.8 1.5 0.00028 20.8 0.4 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.4 NONDRET012590.2_16112102_1 - 0.0043 16.3 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.9 NONDRET012590.2_16112102_1 - 0.0081 15.1 0.4 0.011 14.6 0.4 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 M-factor PF03855.11 NONDRET012590.2_16112102_1 - 1.1 9.3 3.6 2.2 8.4 3.6 1.5 1 0 0 1 1 1 0 M-factor Sperm_Ag_HE2 PF05324.11 NONDRET012590.2_16112102_3 - 0.062 13.6 1.6 0.1 12.8 0.2 2.1 2 0 0 2 2 2 0 Sperm antigen HE2 Pkinase PF00069.23 NONDRET012591.2_16111102_3 - 0.065 12.5 0.1 0.078 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.23 NONDRET012593.2_16111102_3 - 0.0031 16.8 0.1 0.0038 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.23 NONDRET012594.2_16111102_2 - 2.9e-10 39.8 0.0 3.2e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 NONDRET012594.2_16111102_2 - 0.0092 15.1 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 NONDRET012596.2_16111102_2 - 2.8e-10 39.9 0.0 3.2e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 NONDRET012596.2_16111102_2 - 0.0091 15.2 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 NONDRET012598.2_16112102_1 - 2.4e-12 46.6 0.3 3.6e-12 46.1 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 NONDRET012598.2_16112102_1 - 3.9e-05 22.9 0.1 7.1e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 NONDRET012598.2_16112102_1 - 0.00017 21.5 0.4 0.00028 20.8 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.4 NONDRET012598.2_16112102_1 - 0.0042 16.3 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.9 NONDRET012598.2_16112102_1 - 0.008 15.1 0.4 0.011 14.7 0.4 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 M-factor PF03855.11 NONDRET012598.2_16112102_1 - 1.1 9.4 3.6 2.1 8.4 3.6 1.5 1 0 0 1 1 1 0 M-factor Sperm_Ag_HE2 PF05324.11 NONDRET012598.2_16112102_3 - 0.062 13.5 1.6 0.1 12.9 0.2 2.0 2 0 0 2 2 2 0 Sperm antigen HE2 Pkinase PF00069.23 NONDRET012602.2_16111102_3 - 0.0031 16.8 0.1 0.0038 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.23 NONDRET012604.2_16112102_1 - 2.4e-12 46.6 0.3 3.6e-12 46.1 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 NONDRET012604.2_16112102_1 - 3.9e-05 22.9 0.1 7.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 NONDRET012604.2_16112102_1 - 0.00027 20.8 1.5 0.00028 20.8 0.4 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.4 NONDRET012604.2_16112102_1 - 0.0043 16.3 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.9 NONDRET012604.2_16112102_1 - 0.0081 15.1 0.4 0.011 14.6 0.4 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 M-factor PF03855.11 NONDRET012604.2_16112102_1 - 1.1 9.3 3.6 2.2 8.4 3.6 1.5 1 0 0 1 1 1 0 M-factor Sperm_Ag_HE2 PF05324.11 NONDRET012604.2_16112102_3 - 0.069 13.4 1.6 0.1 12.8 0.2 2.0 2 0 0 2 2 2 0 Sperm antigen HE2 Pkinase PF00069.23 NONDRET012605.2_16111102_3 - 4.9e-05 22.7 0.1 4.9e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Rad10 PF03834.12 NONDRET012611.2_16111102_1 - 6.7e-12 45.3 0.1 8.1e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.21 NONDRET012611.2_16111102_2 - 0.032 13.9 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif LcnG-beta PF11632.6 NONDRET012688.2_16111102_3 - 0.053 13.3 0.2 0.072 12.9 0.2 1.2 1 0 0 1 1 1 0 Lactococcin G-beta GluR_Homer-bdg PF10606.7 NONDRET012717.2_16112104_3 - 0.22 11.6 3.4 0.29 11.2 1.2 2.2 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor Transposase_1 PF01359.16 NONDRET012839.1_16112102_2 - 0.1 12.3 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Transposase (partial DDE domain) DBD_Tnp_Hermes PF10683.7 NONDRET012848.1_16111102_1 - 0.047 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain HOOK PF05622.10 NONDRET012856.1_16112102_2 - 0.0034 15.5 0.9 0.0043 15.1 0.9 1.1 1 0 0 1 1 1 1 HOOK protein CD34_antigen PF06365.10 NONDRET012861.1_16112102_3 - 0.17 11.3 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family UPF0560 PF10577.7 NONDRET012863.1_16112102_3 - 1.8 6.9 6.0 2.3 6.5 6.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 I-set PF07679.14 NONDRET012876.1_16114102_3 - 0.00081 19.3 0.1 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.4 NONDRET012876.1_16114102_3 - 0.012 15.8 0.3 0.027 14.7 0.3 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.4 NONDRET012876.1_16114102_3 - 0.06 13.8 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin domain zf-BED PF02892.13 NONDRET012916.1_16111102_1 - 3e-06 27.1 2.3 3e-06 27.1 2.3 1.6 2 0 0 2 2 2 1 BED zinc finger Dimer_Tnp_hAT PF05699.12 NONDRET012916.1_16111102_1 - 0.0049 16.5 0.8 0.013 15.1 0.2 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-met2 PF12907.5 NONDRET012916.1_16111102_1 - 0.24 11.5 1.4 0.39 10.8 1.4 1.3 1 0 0 1 1 1 0 Zinc-binding 7tm_1 PF00001.19 NONDRET012926.1_16112102_3 - 1.1e-37 129.6 20.1 1.4e-37 129.3 20.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Lectin_C PF00059.19 NONDRET012951.1_16111102_2 - 4e-05 24.2 0.0 5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain UPAR_LY6 PF00021.19 NONDRET012991.1_16113102_2 - 0.0039 17.7 14.9 0.014 16.0 14.9 1.9 1 1 0 1 1 1 1 u-PAR/Ly-6 domain FERM_N PF09379.8 NONDRET013010.1_16115102_1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 FERM N-terminal domain stn_TNFRSF12A PF12191.6 NONDRET013064.1_16115102_2 - 0.0004 20.5 0.1 0.00063 19.8 0.1 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF2967 PF11179.6 NONDRET013087.1_16112102_3 - 0.39 10.0 4.0 0.56 9.5 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF2967 PF11179.6 NONDRET013089.1_16112102_2 - 0.33 10.2 4.0 0.47 9.7 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PDE6_gamma PF04868.10 NONDRET013098.1_16112118_1 - 1.5e-22 79.5 0.0 2.4e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit SpoU_methylas_C PF12105.6 NONDRET013106.1_16112102_1 - 0.072 12.7 0.3 0.89 9.2 0.1 2.3 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal Lbh PF15317.4 NONDRET013118.1_16112102_1 - 2.2e-15 57.2 0.7 3.1e-15 56.7 0.6 1.4 1 1 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein MbtH PF03621.11 NONDRET013137.1_16111102_1 - 1.3 8.4 3.8 0.48 9.8 0.7 1.8 2 0 0 2 2 2 0 MbtH-like protein Mucin PF01456.15 NONDRET013168.1_16111102_3 - 0.15 11.9 0.4 0.18 11.7 0.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3020 PF11223.6 NONDRET013181.1_16111102_1 - 0.0068 16.8 1.6 0.01 16.2 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3020) DUF2642 PF10842.6 NONDRET013222.1_16114104_3 - 0.22 11.3 1.4 9.4 6.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2642) Pkinase PF00069.23 NONDRET013252.1_16112102_2 - 2.2e-09 36.9 0.0 0.0068 15.7 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.15 NONDRET013252.1_16112102_2 - 0.12 11.5 0.1 1.7 7.7 0.0 2.5 3 0 0 3 3 3 0 Protein tyrosine kinase TEX12 PF15219.4 NONDRET013259.1_16112104_3 - 2.7e-14 53.1 0.2 4.3e-14 52.5 0.2 1.2 1 0 0 1 1 1 1 Testis-expressed 12 DUF1661 PF07877.9 NONDRET013270.1_16113104_2 - 0.026 14.1 0.2 0.055 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) DUF4213 PF13938.4 NONDRET013275.1_16114102_1 - 0.21 11.7 0.3 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Putative heavy-metal chelation Myb_DNA-bind_5 PF13873.4 NONDRET013289.1_16111102_1 - 1.4e-05 25.0 0.1 2e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain TMEM52 PF14979.4 NONDRET013302.1_16112102_1 - 0.073 12.9 5.1 0.047 13.5 2.4 1.8 2 0 0 2 2 2 0 Transmembrane 52 COPI_C PF06957.9 NONDRET013308.1_16112117_2 - 0.067 11.9 0.0 0.084 11.5 0.0 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Yae1_N PF09811.7 NONDRET013320.1_16112102_1 - 0.73 9.5 5.5 0.4 10.3 1.0 2.2 2 0 0 2 2 2 0 Essential protein Yae1, N terminal DUF788 PF05620.9 NONDRET013369.1_16112102_2 - 0.019 14.7 1.1 0.019 14.7 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF788) CASP_C PF08172.10 NONDRET013395.1_16111102_2 - 2.4 7.3 3.8 3 7.0 3.8 1.1 1 0 0 1 1 1 0 CASP C terminal IL31 PF15209.4 NONDRET013399.1_16111104_1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Interleukin 31 Lectin_C PF00059.19 NONDRET013420.1_16114102_2 - 2.1e-08 34.7 20.2 1.5e-06 28.7 3.6 2.6 2 0 0 2 2 2 2 Lectin C-type domain V-set PF07686.15 NONDRET013422.1_16111102_1 - 0.02 14.9 0.2 0.026 14.5 0.2 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain Dexa_ind PF15198.4 NONDRET013427.1_16112102_1 - 0.077 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Dexamethasone-induced BRX PF08381.9 NONDRET013448.1_16111104_2 - 0.16 11.3 0.3 0.84 8.9 0.0 1.9 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 zf-RVT PF13966.4 NONDRET013450.1_16112104_3 - 0.0018 18.9 0.1 0.0048 17.6 0.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF1033 PF06279.9 NONDRET013450.1_16112104_3 - 0.063 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Arc PF03869.12 NONDRET013496.1_16111117_3 - 0.022 14.5 1.4 3.2 7.5 0.0 3.3 2 1 2 4 4 4 0 Arc-like DNA binding domain ChW PF07538.9 NONDRET013518.1_16111104_3 - 0.085 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Clostridial hydrophobic W SET PF00856.26 NONDRET013523.1_16111102_1 - 0.012 15.9 0.0 0.054 13.7 0.0 1.9 2 0 0 2 2 2 0 SET domain HTH_23 PF13384.4 NONDRET013527.1_16112102_3 - 1.1e-07 31.3 3.1 5.2e-07 29.1 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.16 NONDRET013527.1_16112102_3 - 8e-06 25.9 0.5 2.3e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.4 NONDRET013527.1_16112102_3 - 0.00018 21.5 2.0 0.00059 19.8 0.1 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.4 NONDRET013527.1_16112102_3 - 0.00018 21.3 2.5 0.00021 21.1 0.4 2.1 2 0 0 2 2 2 1 Winged helix-turn helix LacI PF00356.19 NONDRET013527.1_16112102_3 - 0.015 14.9 1.8 0.045 13.4 0.6 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.4 NONDRET013527.1_16112102_3 - 0.019 14.3 1.3 0.4 10.0 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.25 NONDRET013527.1_16112102_3 - 0.022 14.6 0.7 0.81 9.6 0.2 2.4 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_DeoR PF08220.10 NONDRET013527.1_16112102_3 - 0.029 14.0 0.2 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_Crp_2 PF13545.4 NONDRET013527.1_16112102_3 - 0.041 13.7 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_38 PF13936.4 NONDRET013527.1_16112102_3 - 0.059 13.1 3.0 0.89 9.3 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.4 NONDRET013527.1_16112102_3 - 0.11 12.8 0.3 0.21 11.8 0.3 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain Crp PF00325.18 NONDRET013527.1_16112102_3 - 0.15 11.6 0.4 0.49 10.0 0.4 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_32 PF13565.4 NONDRET013527.1_16112102_3 - 0.22 12.0 0.2 0.22 12.0 0.2 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_23 PF13384.4 NONDRET013528.1_16112102_1 - 1.2e-08 34.4 0.3 3e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.16 NONDRET013528.1_16112102_1 - 4.8e-06 26.6 0.8 1.4e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.4 NONDRET013528.1_16112102_1 - 3e-05 23.9 0.1 0.00036 20.5 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.4 NONDRET013528.1_16112102_1 - 0.00011 22.1 2.5 0.00012 21.8 0.4 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.4 NONDRET013528.1_16112102_1 - 0.0084 15.4 1.3 0.26 10.6 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.25 NONDRET013528.1_16112102_1 - 0.012 15.4 1.0 0.55 10.1 0.3 2.4 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family LacI PF00356.19 NONDRET013528.1_16112102_1 - 0.013 15.1 2.6 0.03 14.0 0.6 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_DeoR PF08220.10 NONDRET013528.1_16112102_1 - 0.013 15.0 0.2 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_Crp_2 PF13545.4 NONDRET013528.1_16112102_1 - 0.024 14.5 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_38 PF13936.4 NONDRET013528.1_16112102_1 - 0.028 14.1 3.0 0.59 9.9 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.4 NONDRET013528.1_16112102_1 - 0.066 13.4 0.4 0.15 12.3 0.4 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.4 NONDRET013528.1_16112102_1 - 0.068 13.7 0.2 0.13 12.8 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.13 NONDRET013528.1_16112102_1 - 0.089 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.5 NONDRET013528.1_16112102_1 - 0.22 11.6 1.0 0.67 10.0 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Crp PF00325.18 NONDRET013528.1_16112102_1 - 0.72 9.4 2.9 0.33 10.5 0.4 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family V-set PF07686.15 NONDRET013535.1_16112102_2 - 4.9e-11 42.6 0.0 6.9e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 NONDRET013535.1_16112102_2 - 0.00028 21.3 0.0 0.00048 20.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 NONDRET013535.1_16112102_2 - 0.032 14.5 0.0 0.22 11.7 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.14 NONDRET013535.1_16112102_2 - 0.049 13.6 0.0 0.084 12.8 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain HTH_23 PF13384.4 NONDRET013541.1_16111102_2 - 0.00012 21.6 0.1 0.00018 21.1 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.6 NONDRET013541.1_16111102_2 - 0.00055 19.6 0.0 0.00084 19.0 0.0 1.2 1 0 0 1 1 1 1 Tc3 transposase HTH_38 PF13936.4 NONDRET013541.1_16111102_2 - 0.00057 19.5 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.4 NONDRET013541.1_16111102_2 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_31 PF13560.4 NONDRET013541.1_16111102_2 - 0.0021 18.2 0.4 0.015 15.5 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_ECF PF07638.9 NONDRET013541.1_16111102_2 - 0.0071 16.1 0.0 0.0082 15.9 0.0 1.1 1 0 0 1 1 1 1 ECF sigma factor HTH_29 PF13551.4 NONDRET013541.1_16111102_2 - 0.022 14.7 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix HTH_AraC PF00165.21 NONDRET013541.1_16111102_2 - 0.026 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_3 PF01381.20 NONDRET013541.1_16111102_2 - 0.046 13.7 0.1 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix HTH_psq PF05225.14 NONDRET013541.1_16111102_2 - 0.11 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_28 PF13518.4 NONDRET013541.1_16111102_2 - 0.15 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4806 PF16064.3 NONDRET013545.1_16112102_1 - 3.6e-09 36.7 0.1 7.3e-09 35.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4806) F-box PF00646.31 NONDRET013548.1_16112102_3 - 0.079 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 F-box domain DDE_Tnp_4 PF13359.4 NONDRET013625.1_16111102_1 - 0.026 14.1 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF4189 PF13827.4 NONDRET013652.1_16112104_3 - 0.036 14.4 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4189) DUF4303 PF14136.4 NONDRET013653.1_16112102_2 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4303) DUF4303 PF14136.4 NONDRET013654.1_16112102_1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4303) PEX-2N PF09263.8 NONDRET013666.1_16112102_2 - 0.066 13.3 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal Phospholamban PF04272.12 NONDRET013741.1_16113118_1 - 1.5e-31 107.4 6.8 1.5e-31 107.4 6.8 1.7 2 0 0 2 2 2 1 Phospholamban Sarcolipin PF05366.9 NONDRET013741.1_16113118_1 - 0.0046 16.5 3.6 0.0095 15.5 3.6 1.4 1 0 0 1 1 1 1 Sarcolipin zf-RVT PF13966.4 NONDRET013754.1_16111102_2 - 0.029 15.1 0.2 0.033 14.9 0.2 1.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF1440 PF07274.10 NONDRET013775.1_16111102_1 - 0.16 12.2 0.1 0.22 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) EspG PF06872.9 NONDRET013775.1_16111102_3 - 0.088 11.2 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 EspG protein zf-H2C2_2 PF13465.4 NONDRET013779.1_16111118_1 - 3.7e-11 42.8 19.7 8.6e-09 35.3 3.0 3.8 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET013779.1_16111118_1 - 3.2e-10 39.8 10.6 0.00013 22.1 4.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET013779.1_16111118_1 - 8.9e-06 26.0 13.3 0.01 16.5 3.4 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.4 NONDRET013779.1_16111118_1 - 2.8e-05 23.8 9.2 0.041 13.7 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.3 NONDRET013779.1_16111118_1 - 0.00025 20.6 5.0 0.003 17.1 3.2 2.4 2 1 0 2 2 2 1 zinc-finger C2H2-type C1_4 PF07975.10 NONDRET013779.1_16111118_1 - 0.011 15.8 6.9 0.25 11.5 0.1 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain zf-H2C2_5 PF13909.4 NONDRET013779.1_16111118_1 - 0.017 14.8 1.6 0.017 14.8 1.6 3.6 4 1 0 4 4 4 0 C2H2-type zinc-finger domain CpXC PF14353.4 NONDRET013779.1_16111118_1 - 0.022 14.6 4.3 0.35 10.8 1.9 2.2 1 1 1 2 2 2 0 CpXC protein PyrI_C PF02748.13 NONDRET013779.1_16111118_1 - 0.032 14.0 0.8 0.032 14.0 0.8 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.6 NONDRET013779.1_16111118_1 - 0.035 14.3 9.5 1.8 8.8 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LIM PF00412.20 NONDRET013779.1_16111118_1 - 0.042 14.0 8.3 2.9 8.1 9.4 2.3 1 1 1 2 2 2 0 LIM domain zf-met PF12874.5 NONDRET013779.1_16111118_1 - 0.05 13.9 11.3 0.32 11.3 3.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-trcl PF13451.4 NONDRET013779.1_16111118_1 - 0.084 12.6 3.9 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-AN1 PF01428.14 NONDRET013779.1_16111118_1 - 0.2 11.7 9.9 1 9.4 1.1 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.3 NONDRET013779.1_16111118_1 - 0.47 10.8 11.1 2.3 8.6 4.3 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger IBR PF01485.19 NONDRET013779.1_16111118_1 - 1.2 9.3 10.7 8.9 6.5 10.7 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Evr1_Alr PF04777.11 NONDRET013779.1_16111118_1 - 1.2 9.5 7.1 4 7.9 2.1 2.2 1 1 1 2 2 2 0 Erv1 / Alr family Ribosomal_L37ae PF01780.17 NONDRET013779.1_16111118_1 - 1.4 8.9 7.7 0.4 10.7 1.6 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family HNH PF01844.21 NONDRET013779.1_16111118_1 - 2.3 8.3 10.4 5.7 7.1 1.4 3.0 3 0 0 3 3 3 0 HNH endonuclease zf-H2C2_2 PF13465.4 NONDRET013781.1_16112117_2 - 8e-17 60.7 23.1 3.5e-10 39.7 3.1 3.8 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET013781.1_16112117_2 - 1.9e-09 37.3 23.5 5.3e-07 29.6 3.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET013781.1_16112117_2 - 1.2e-07 31.8 11.6 0.00015 22.2 2.2 3.8 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.4 NONDRET013781.1_16112117_2 - 2.1e-05 24.2 20.0 0.0032 17.3 3.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.3 NONDRET013781.1_16112117_2 - 0.0002 20.9 15.6 0.0041 16.7 3.3 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.6 NONDRET013781.1_16112117_2 - 0.0049 17.0 11.1 0.22 11.8 2.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 NONDRET013781.1_16112117_2 - 0.01 16.0 13.2 0.26 11.6 4.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CpXC PF14353.4 NONDRET013781.1_16112117_2 - 0.014 15.3 0.5 0.014 15.3 0.5 2.8 1 1 0 2 2 2 0 CpXC protein Fer4_9 PF13187.4 NONDRET013781.1_16112117_2 - 0.39 10.8 9.7 3 7.9 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn-ribbon_8 PF09723.8 NONDRET013781.1_16112117_2 - 0.98 9.5 11.5 4.9 7.2 4.4 2.6 1 1 1 2 2 2 0 Zinc ribbon domain zf-AN1 PF01428.14 NONDRET013781.1_16112117_2 - 2 8.5 13.6 3.1 7.9 0.6 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger ADK_lid PF05191.12 NONDRET013781.1_16112117_2 - 2.1 8.3 10.7 2.4e+02 1.7 10.7 2.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-TFIIB PF13453.4 NONDRET013781.1_16112117_2 - 2.7 7.2 7.1 15 4.9 0.2 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger PyrI_C PF02748.13 NONDRET013781.1_16112117_2 - 4.5 7.1 14.0 0.14 12.0 2.6 2.9 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain LIM PF00412.20 NONDRET013781.1_16112117_2 - 5.1 7.3 15.0 2 8.6 7.8 2.7 1 1 1 2 2 2 0 LIM domain zf-H2C2_2 PF13465.4 NONDRET013782.1_16113118_2 - 3.4e-61 201.0 79.0 5.1e-10 39.2 0.4 10.7 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET013782.1_16113118_2 - 1e-45 151.5 97.7 2.5e-07 30.6 3.4 9.8 10 0 0 10 10 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET013782.1_16113118_2 - 1.8e-30 102.8 87.3 0.00021 21.7 2.5 10.0 10 0 0 10 10 9 9 C2H2-type zinc finger zf-C2H2_11 PF16622.3 NONDRET013782.1_16113118_2 - 4e-11 42.3 70.1 0.0063 16.1 4.6 9.3 9 0 0 9 9 9 6 zinc-finger C2H2-type zf-C2H2_jaz PF12171.6 NONDRET013782.1_16113118_2 - 8.5e-10 38.6 49.6 0.37 11.0 2.8 9.5 9 0 0 9 9 9 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 NONDRET013782.1_16113118_2 - 5e-09 35.8 79.1 0.064 13.1 2.2 10.5 10 1 0 10 10 10 7 C2H2-type zinc finger zf-LYAR PF08790.9 NONDRET013782.1_16113118_2 - 3.4e-06 26.7 50.9 0.018 14.8 1.6 9.0 9 0 0 9 9 9 4 LYAR-type C2HC zinc finger zf-met PF12874.5 NONDRET013782.1_16113118_2 - 1.4e-05 25.2 74.2 0.025 14.8 4.4 9.9 9 1 1 10 10 10 4 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.8 NONDRET013782.1_16113118_2 - 1.7e-05 24.7 36.0 0.5 10.4 0.1 7.4 4 2 5 9 9 9 6 Zinc ribbon domain E7 PF00527.16 NONDRET013782.1_16113118_2 - 0.03 14.4 0.7 0.22 11.6 0.7 2.5 1 0 0 1 1 1 0 E7 protein, Early protein ADK_lid PF05191.12 NONDRET013782.1_16113118_2 - 0.06 13.2 34.4 0.17 11.8 0.4 6.0 5 2 0 5 5 5 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.3 NONDRET013782.1_16113118_2 - 0.39 11.3 36.5 1.4 9.6 1.2 5.7 1 1 3 6 6 6 0 zinc-ribbon family zf-trcl PF13451.4 NONDRET013782.1_16113118_2 - 0.82 9.5 38.0 2.1 8.2 0.1 8.8 8 1 0 8 8 8 0 Probable zinc-ribbon domain DUF3268 PF11672.6 NONDRET013782.1_16113118_2 - 1.6 9.0 22.0 0.31 11.3 0.3 4.5 3 2 0 4 4 4 0 zinc-finger-containing domain zf-C2HC_2 PF13913.4 NONDRET013782.1_16113118_2 - 1.8 8.4 51.0 0.42 10.5 0.3 9.2 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.5 NONDRET013782.1_16113118_2 - 1.9 8.8 56.5 0.35 11.1 1.9 8.6 2 1 5 8 8 8 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.16 NONDRET013782.1_16113118_2 - 3.3 7.7 37.1 11 6.1 0.3 9.1 9 0 0 9 9 9 0 XPA protein N-terminal EphA2_TM PF14575.4 NONDRET013797.1_16111102_3 - 0.0031 18.1 0.4 0.0031 18.1 0.4 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain AgrB PF04647.13 NONDRET013797.1_16111102_3 - 0.067 12.4 15.9 0.082 12.1 15.9 1.1 1 0 0 1 1 1 0 Accessory gene regulator B AA_permease_2 PF13520.4 NONDRET013797.1_16111102_3 - 0.1 11.3 15.7 0.1 11.2 15.7 1.0 1 0 0 1 1 1 0 Amino acid permease DUF4131 PF13567.4 NONDRET013797.1_16111102_3 - 0.25 10.8 1.2 0.33 10.4 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1510 PF07423.9 NONDRET013797.1_16111102_3 - 0.91 8.8 7.8 1.3 8.3 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2207 PF09972.7 NONDRET013797.1_16111102_3 - 4.6 5.8 9.0 5.2 5.6 9.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AC_N PF16214.3 NONDRET013797.1_16111102_3 - 5.4 5.9 7.9 6.2 5.7 7.9 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region zf-DHHC PF01529.18 NONDRET013797.1_16111102_3 - 8.3 6.4 11.5 0.77 9.7 7.0 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Sigma_reg_N PF13800.4 NONDRET013797.1_16111102_3 - 9.4 6.5 20.0 0.31 11.2 12.6 1.9 1 1 1 2 2 2 0 Sigma factor regulator N-terminal HTH_Tnp_Tc3_2 PF01498.16 NONDRET013887.1_16112102_1 - 5.8e-09 35.9 7.2 6.8e-09 35.7 3.1 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.4 NONDRET013887.1_16112102_1 - 4.5e-08 32.9 0.2 3.1e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.4 NONDRET013887.1_16112102_1 - 1.2e-07 32.0 0.5 3.2e-07 30.7 0.5 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.4 NONDRET013887.1_16112102_1 - 5.9e-07 29.4 0.2 5.4e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.4 NONDRET013887.1_16112102_1 - 9.7e-05 21.9 0.2 0.0084 15.7 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.4 NONDRET013887.1_16112102_1 - 0.00032 19.9 0.0 0.044 13.1 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.14 NONDRET013887.1_16112102_1 - 0.0082 15.5 0.3 0.045 13.2 0.0 2.3 2 1 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.10 NONDRET013887.1_16112102_1 - 0.014 15.0 0.1 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_WhiA PF02650.12 NONDRET013887.1_16112102_1 - 0.014 15.6 0.3 0.03 14.5 0.3 1.6 1 0 0 1 1 1 0 WhiA C-terminal HTH domain HTH_38 PF13936.4 NONDRET013887.1_16112102_1 - 0.023 14.3 0.7 1.3 8.7 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.17 NONDRET013887.1_16112102_1 - 0.041 13.6 0.2 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_30 PF13556.4 NONDRET013887.1_16112102_1 - 0.041 13.6 0.2 0.88 9.3 0.3 2.3 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.4 NONDRET013887.1_16112102_1 - 0.041 13.3 0.9 2 7.9 0.3 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF4303 PF14136.4 NONDRET013920.1_16112102_1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) NTF2 PF02136.18 NONDRET013937.1_16114104_2 - 0.046 14.1 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SWIM PF04434.15 NONDRET013956.1_16112102_1 - 0.03 13.9 1.7 0.03 13.9 1.7 2.5 2 0 0 2 2 2 0 SWIM zinc finger DUF4806 PF16064.3 NONDRET014022.1_16111102_1 - 0.0029 17.7 0.1 0.0038 17.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) V-set PF07686.15 NONDRET014045.1_16112118_1 - 5.7e-08 32.8 0.7 1.2e-07 31.7 0.7 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 NONDRET014045.1_16112118_1 - 7.3e-06 26.4 1.9 1.8e-05 25.1 0.9 2.2 1 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 NONDRET014045.1_16112118_1 - 0.00025 21.0 1.4 0.00025 21.0 1.4 2.1 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.14 NONDRET014045.1_16112118_1 - 0.00059 19.7 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain G6B PF15096.4 NONDRET014045.1_16112118_1 - 0.0043 16.7 0.9 0.054 13.1 0.1 2.5 1 1 2 3 3 3 1 G6B family Ig_2 PF13895.4 NONDRET014045.1_16112118_1 - 0.0087 16.3 1.3 0.0087 16.3 1.3 2.1 2 1 0 2 2 2 1 Immunoglobulin domain IncA PF04156.12 NONDRET014045.1_16112118_1 - 0.028 14.1 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 IncA protein CD34_antigen PF06365.10 NONDRET014045.1_16112118_1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Izumo-Ig PF16706.3 NONDRET014045.1_16112118_1 - 0.061 13.2 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain TMEM154 PF15102.4 NONDRET014045.1_16112118_1 - 0.3 10.9 2.0 1.4 8.7 2.0 2.1 1 1 0 1 1 1 0 TMEM154 protein family zf-H2C2_2 PF13465.4 NONDRET014056.1_16112118_3 - 3.4e-42 140.9 50.7 1.9e-11 43.7 0.9 7.2 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET014056.1_16112118_3 - 6.6e-27 92.3 57.1 1.8e-08 34.2 2.3 7.2 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET014056.1_16112118_3 - 7.6e-18 63.5 56.0 2.6e-05 24.5 1.6 7.8 8 0 0 8 8 7 6 C2H2-type zinc finger zf-H2C2_5 PF13909.4 NONDRET014056.1_16112118_3 - 1.4e-07 31.0 6.6 0.00012 21.6 0.2 9.5 8 2 0 8 8 7 2 C2H2-type zinc-finger domain GAGA PF09237.9 NONDRET014056.1_16112118_3 - 1.4e-07 31.1 7.7 0.095 12.4 0.0 4.3 3 1 1 4 4 4 2 GAGA factor DZR PF12773.5 NONDRET014056.1_16112118_3 - 8.6e-07 28.8 22.2 0.091 12.7 5.0 4.0 2 1 1 3 3 3 3 Double zinc ribbon zf-C2H2_11 PF16622.3 NONDRET014056.1_16112118_3 - 1.5e-06 27.7 27.6 0.0033 17.0 1.2 5.1 6 0 0 6 6 5 3 zinc-finger C2H2-type Zn-ribbon_8 PF09723.8 NONDRET014056.1_16112118_3 - 1.3e-05 25.0 25.0 0.0087 16.0 0.5 5.4 3 2 2 5 5 5 3 Zinc ribbon domain zf-C2H2_6 PF13912.4 NONDRET014056.1_16112118_3 - 5e-05 23.0 47.2 0.0079 16.0 0.8 7.4 7 2 0 7 7 7 4 C2H2-type zinc finger zf-C2HE PF16278.3 NONDRET014056.1_16112118_3 - 6.4e-05 23.2 45.1 0.0052 17.1 1.1 6.9 1 1 6 7 7 7 4 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.6 NONDRET014056.1_16112118_3 - 0.00028 21.0 33.9 0.17 12.1 0.1 6.9 7 1 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.3 NONDRET014056.1_16112118_3 - 0.00057 20.4 24.0 0.017 15.8 2.5 4.1 2 1 3 5 5 5 3 zinc-ribbon family zf-met PF12874.5 NONDRET014056.1_16112118_3 - 0.002 18.3 47.2 0.088 13.1 0.8 6.8 7 0 0 7 7 6 4 Zinc-finger of C2H2 type zf-LYAR PF08790.9 NONDRET014056.1_16112118_3 - 0.0027 17.5 23.5 0.016 15.0 0.7 6.2 6 0 0 6 6 6 1 LYAR-type C2HC zinc finger HypA PF01155.17 NONDRET014056.1_16112118_3 - 0.0091 15.9 20.7 0.97 9.3 0.8 4.1 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.12 NONDRET014056.1_16112118_3 - 0.017 15.0 0.3 0.017 15.0 0.3 4.6 3 2 2 5 5 4 0 Adenylate kinase, active site lid BHD_1 PF10403.7 NONDRET014056.1_16112118_3 - 0.024 14.3 2.6 22 4.9 0.0 3.7 2 1 0 3 3 3 0 Rad4 beta-hairpin domain 1 DUF3268 PF11672.6 NONDRET014056.1_16112118_3 - 0.025 14.8 17.5 1.9 8.7 0.7 4.2 2 1 1 4 4 4 0 zinc-finger-containing domain XPA_N PF01286.16 NONDRET014056.1_16112118_3 - 0.14 12.1 22.9 0.34 10.8 0.1 6.2 7 0 0 7 7 7 0 XPA protein N-terminal AAA_14 PF13173.4 NONDRET014056.1_16112118_3 - 0.2 11.5 0.7 0.88 9.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain Zn_Tnp_IS1595 PF12760.5 NONDRET014056.1_16112118_3 - 0.42 10.5 30.3 0.71 9.8 2.4 4.4 3 1 1 4 4 4 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.4 NONDRET014056.1_16112118_3 - 0.45 10.3 25.6 3.8 7.4 0.1 6.6 6 1 0 6 6 6 0 Nudix N-terminal PHD PF00628.27 NONDRET014056.1_16112118_3 - 0.56 10.0 24.7 17 5.3 2.5 5.7 4 2 1 5 5 5 0 PHD-finger zf-RING_7 PF02591.13 NONDRET014056.1_16112118_3 - 0.78 9.9 19.7 4.2 7.5 0.1 6.2 7 0 0 7 7 7 0 C4-type zinc ribbon domain PknG_rubred PF16919.3 NONDRET014056.1_16112118_3 - 0.86 9.6 11.7 3 7.8 0.6 3.9 1 1 3 4 4 4 0 Protein kinase G rubredoxin domain zf-C2H2_2 PF12756.5 NONDRET014056.1_16112118_3 - 2.3 8.5 36.4 0.67 10.2 1.5 6.1 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) TerY_C PF15616.4 NONDRET014056.1_16112118_3 - 3.1 7.8 11.1 0.71 9.9 1.5 3.4 1 1 2 3 3 3 0 TerY-C metal binding domain SIR2 PF02146.15 NONDRET014056.1_16112118_3 - 4.6 7.0 16.4 1.6e+02 1.9 16.4 2.5 1 1 0 1 1 1 0 Sir2 family zinc-ribbons_6 PF07191.10 NONDRET014056.1_16112118_3 - 7.3 6.5 27.6 1.6e+04 -15.7 27.6 5.7 1 1 0 1 1 0 0 zinc-ribbons zf-HYPF PF07503.10 NONDRET014056.1_16112118_3 - 8.7 6.1 0.0 8.7 6.1 0.0 5.7 7 0 0 7 7 7 0 HypF finger GST_N_4 PF17172.2 NONDRET014075.1_16112102_2 - 0.062 13.9 0.0 0.097 13.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF4303 PF14136.4 NONDRET014082.1_16114104_1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Flu_M1 PF00598.17 NONDRET014083.1_16112102_2 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M1) Dynamin_N PF00350.21 NONDRET014116.1_16111102_1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 1 0 1 1 1 0 Dynamin family HTH_OrfB_IS605 PF12323.6 NONDRET014116.1_16111102_2 - 0.077 12.4 0.4 0.18 11.2 0.4 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SWIM PF04434.15 NONDRET014119.1_16112102_2 - 0.0094 15.5 1.7 0.025 14.1 1.7 1.7 1 0 0 1 1 1 1 SWIM zinc finger AAA PF00004.27 NONDRET014137.1_16111118_1 - 1e-11 45.3 0.0 1.1e-11 45.2 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RVT_1 PF00078.25 NONDRET014156.1_16112102_2 - 6.7e-10 38.7 0.0 9.4e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4303 PF14136.4 NONDRET014167.1_16113102_3 - 0.099 12.3 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) zf-HC5HC2H PF13771.4 NONDRET014173.1_16111102_3 - 0.0063 16.6 1.2 0.009 16.1 1.2 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain Topo_Zn_Ribbon PF08272.9 NONDRET014191.1_16113117_1 - 0.087 12.4 6.4 1.1e+02 2.5 0.0 5.5 6 0 0 6 6 6 0 Topoisomerase I zinc-ribbon-like zf-H2C2_2 PF13465.4 NONDRET014191.1_16113117_2 - 9.3e-87 281.8 62.2 9.9e-10 38.3 0.8 11.3 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET014191.1_16113117_2 - 4.4e-65 212.6 83.6 1e-06 28.7 2.9 11.0 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET014191.1_16113117_2 - 2.6e-43 142.8 76.3 5.2e-05 23.6 3.5 10.9 11 0 0 11 11 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.4 NONDRET014191.1_16113117_2 - 2.4e-22 78.2 60.5 0.01 15.6 2.0 10.8 11 0 0 11 11 10 10 C2H2-type zinc finger zf-LYAR PF08790.9 NONDRET014191.1_16113117_2 - 7e-20 70.5 58.7 0.041 13.7 0.5 10.4 10 0 0 10 10 10 10 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.6 NONDRET014191.1_16113117_2 - 1.5e-17 63.3 30.2 0.38 11.0 0.1 10.3 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.3 NONDRET014191.1_16113117_2 - 3.6e-15 56.0 69.6 0.13 12.6 1.8 10.4 1 1 9 10 10 10 9 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.3 NONDRET014191.1_16113117_2 - 7.8e-12 44.6 70.4 0.00029 20.4 2.7 10.3 10 0 0 10 10 10 7 zinc-finger C2H2-type zf-Sec23_Sec24 PF04810.13 NONDRET014191.1_16113117_2 - 1.3e-11 44.2 37.9 0.048 13.6 0.0 9.8 7 3 3 10 10 10 5 Sec23/Sec24 zinc finger ADK_lid PF05191.12 NONDRET014191.1_16113117_2 - 1.8e-08 34.2 18.5 0.034 14.0 0.0 7.6 3 3 6 9 9 9 4 Adenylate kinase, active site lid zf-C2H2_2 PF12756.5 NONDRET014191.1_16113117_2 - 7.6e-08 32.5 52.8 2.6 8.3 0.5 10.2 1 1 9 10 10 10 1 C2H2 type zinc-finger (2 copies) HypA PF01155.17 NONDRET014191.1_16113117_2 - 5.8e-07 29.4 31.4 0.63 9.9 9.1 6.1 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_7 PF02591.13 NONDRET014191.1_16113117_2 - 9.8e-07 28.7 24.7 4.3 7.5 0.0 9.9 10 0 0 10 10 10 1 C4-type zinc ribbon domain XPA_N PF01286.16 NONDRET014191.1_16113117_2 - 2.5e-06 27.3 43.3 0.95 9.4 0.0 10.0 10 0 0 10 10 10 3 XPA protein N-terminal LIM PF00412.20 NONDRET014191.1_16113117_2 - 3.1e-06 27.2 47.7 5.8 7.1 2.6 9.8 4 1 6 10 10 10 0 LIM domain zf-trcl PF13451.4 NONDRET014191.1_16113117_2 - 8.7e-06 25.4 49.2 1.9 8.3 0.1 10.4 9 1 0 9 9 9 1 Probable zinc-ribbon domain zf-AN1 PF01428.14 NONDRET014191.1_16113117_2 - 1.5e-05 24.9 54.3 5 7.2 0.2 10.3 8 2 2 10 10 10 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.8 NONDRET014191.1_16113117_2 - 3.2e-05 23.8 42.4 0.46 10.5 2.0 7.6 1 1 9 10 10 10 6 Zinc ribbon domain DUF4476 PF14771.4 NONDRET014191.1_16113117_2 - 0.00012 22.2 16.2 6.4 7.0 0.0 7.8 2 1 8 10 10 10 0 Domain of unknown function (DUF4476) zinc_ribbon_15 PF17032.3 NONDRET014191.1_16113117_2 - 0.00013 22.5 37.0 0.11 13.1 0.6 6.0 1 1 7 8 8 8 3 zinc-ribbon family PknG_rubred PF16919.3 NONDRET014191.1_16113117_2 - 0.00021 21.3 30.8 0.059 13.4 0.3 5.8 1 1 5 6 6 6 3 Protein kinase G rubredoxin domain YhfH PF14149.4 NONDRET014191.1_16113117_2 - 0.00086 19.1 38.2 4.8 7.1 0.1 9.4 10 0 0 10 10 10 0 YhfH-like protein GAGA PF09237.9 NONDRET014191.1_16113117_2 - 0.0012 18.5 16.7 0.67 9.7 0.0 7.3 2 1 7 9 9 9 1 GAGA factor zf-FCS PF06467.12 NONDRET014191.1_16113117_2 - 0.0017 18.1 50.9 2.6 8.0 0.1 9.3 9 0 0 9 9 9 1 MYM-type Zinc finger with FCS sequence motif zf-CHY PF05495.10 NONDRET014191.1_16113117_2 - 0.002 18.5 49.1 0.87 10.1 3.4 6.4 1 1 6 7 7 7 1 CHY zinc finger zf-met PF12874.5 NONDRET014191.1_16113117_2 - 0.013 15.7 74.9 0.56 10.5 1.4 10.3 10 0 0 10 10 10 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.4 NONDRET014191.1_16113117_2 - 0.079 12.8 42.5 0.34 10.7 0.5 9.5 10 0 0 10 10 9 0 zinc-finger of a C2HC-type zf-Di19 PF05605.10 NONDRET014191.1_16113117_2 - 0.2 11.8 40.3 0.4 10.9 1.6 6.6 3 2 3 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.8 NONDRET014191.1_16113117_2 - 0.27 11.8 34.6 12 6.5 0.1 9.4 2 2 6 9 9 9 0 Protein of unknown function (FYDLN_acid) zf-BED PF02892.13 NONDRET014191.1_16113117_2 - 0.32 10.9 58.5 1.6 8.7 1.5 9.5 1 1 8 9 9 9 0 BED zinc finger DUF3268 PF11672.6 NONDRET014191.1_16113117_2 - 1.4 9.1 24.7 5.9 7.1 0.3 5.2 2 2 2 6 6 6 0 zinc-finger-containing domain zinc_ribbon_4 PF13717.4 NONDRET014191.1_16113117_2 - 2.6 7.9 47.6 28 4.6 0.3 9.6 9 1 1 10 10 10 0 zinc-ribbon domain zf-H2C2_5 PF13909.4 NONDRET014191.1_16113117_2 - 2.9 7.6 94.5 0.13 11.9 0.7 12.5 11 6 0 11 11 11 0 C2H2-type zinc-finger domain zinc_ribbon_9 PF14369.4 NONDRET014191.1_16113117_2 - 6.9 6.9 33.9 26 5.1 0.1 9.3 9 1 1 10 10 10 0 zinc-ribbon BolA PF01722.16 NONDRET014191.1_16113117_2 - 9.5 6.5 15.5 21 5.4 0.1 5.0 3 1 1 5 5 5 0 BolA-like protein zf-H2C2_2 PF13465.4 NONDRET014191.1_16113117_3 - 4e-11 42.7 8.9 6.6e-07 29.4 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.24 NONDRET014191.1_16113117_3 - 1.6e-09 37.5 11.1 0.00018 21.6 0.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 NONDRET014191.1_16113117_3 - 0.00016 22.1 9.5 0.053 14.2 0.2 4.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 NONDRET014191.1_16113117_3 - 1 9.6 11.2 0.58 10.4 0.4 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Toxin_35 PF10530.7 NONDRET014202.1_16115102_2 - 0.5 10.2 3.8 1.4 8.8 3.8 1.7 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold Peptidase_C48 PF02902.17 NONDRET014202.1_16115102_3 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF4806 PF16064.3 NONDRET014203.1_16112117_1 - 4.7e-09 36.3 0.0 9.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) DUF4591 PF15261.4 NONDRET014203.1_16112117_1 - 0.52 10.9 5.0 1 9.9 5.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4591) DUF4303 PF14136.4 NONDRET014206.1_16114102_1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) UDPGT PF00201.16 NONDRET014223.1_16113117_2 - 1e-33 116.8 0.0 2.1e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Prok-RING_4 PF14447.4 NONDRET014237.1_16115117_1 - 0.024 14.4 0.4 0.051 13.3 0.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.10 NONDRET014237.1_16115117_1 - 0.16 12.2 1.4 0.54 10.5 0.4 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MAP7 PF05672.9 NONDRET014273.1_16112102_3 - 1.4e-15 57.3 21.1 2.2e-15 56.6 21.1 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family MAP7 PF05672.9 NONDRET014274.1_16112102_3 - 6.3e-10 38.9 10.8 8.2e-10 38.5 10.8 1.1 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Atrophin-1 PF03154.13 NONDRET014274.1_16112102_3 - 0.12 10.5 2.7 0.14 10.2 2.7 1.0 1 0 0 1 1 1 0 Atrophin-1 family MAP7 PF05672.9 NONDRET014275.1_16113102_3 - 1.5e-19 70.2 13.4 2.1e-19 69.7 13.4 1.1 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family MAP7 PF05672.9 NONDRET014278.1_16112102_3 - 6.2e-10 38.9 10.8 8.2e-10 38.5 10.8 1.1 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Atrophin-1 PF03154.13 NONDRET014278.1_16112102_3 - 0.32 9.1 4.0 0.4 8.8 4.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family MAP7 PF05672.9 NONDRET014279.1_16112102_3 - 1.4e-15 57.3 21.1 2.2e-15 56.6 21.1 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Chromo PF00385.22 NONDRET014289.1_16112102_3 - 3.4e-10 39.5 0.0 4.8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.4 NONDRET014289.1_16112102_3 - 0.13 12.3 0.2 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF4303 PF14136.4 NONDRET014301.1_16111102_1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) HTH_Tnp_Tc3_2 PF01498.16 NONDRET014313.1_16115102_1 - 0.00018 21.6 0.1 0.0004 20.4 0.0 1.6 2 0 0 2 2 2 1 Transposase MAP7 PF05672.9 NONDRET014338.1_16112102_2 - 1.2e-20 73.8 17.2 1.6e-20 73.4 17.2 1.1 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family MAP7 PF05672.9 NONDRET014340.1_16113102_2 - 8.4e-21 74.2 13.9 1.2e-20 73.8 13.9 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family DUF4806 PF16064.3 NONDRET014363.1_16112102_2 - 0.0036 17.4 0.0 0.0072 16.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) F-box PF00646.31 NONDRET014443.1_16111102_2 - 0.00015 21.4 3.2 0.0003 20.5 0.0 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.5 NONDRET014443.1_16111102_2 - 0.001 18.8 1.2 0.0053 16.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like Lipase_GDSL_2 PF13472.4 NONDRET014454.1_16112102_1 - 6.4e-08 33.1 0.0 7.9e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.20 NONDRET014454.1_16112102_1 - 0.017 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase zf-LSD1 PF06943.10 NONDRET014461.1_16111102_3 - 5.5 6.8 8.1 35 4.2 1.0 3.8 1 1 2 3 3 3 0 LSD1 zinc finger SKG6 PF08693.8 NONDRET014497.1_16112102_2 - 0.71 9.2 3.5 2.1 7.7 3.5 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4843 PF16132.3 NONDRET014503.1_16111102_3 - 0.019 14.4 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4843) Lipase_GDSL_2 PF13472.4 NONDRET014515.1_16112102_1 - 7.7e-08 32.8 0.0 9.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.20 NONDRET014515.1_16112102_1 - 0.021 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase HTH_Tnp_Tc3_2 PF01498.16 NONDRET014527.1_16112102_2 - 1e-09 38.3 0.3 1.5e-09 37.8 0.3 1.2 1 0 0 1 1 1 1 Transposase Glycoprotein_G PF00802.17 NONDRET014552.1_16111102_1 - 6.6 5.9 5.7 7.1 5.8 5.7 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G TAFA PF12020.6 NONDRET014625.1_16115102_1 - 4.1e-46 155.2 12.3 8.8e-46 154.2 12.3 1.6 1 0 0 1 1 1 1 TAFA family YmcE_antitoxin PF15939.3 NONDRET014628.1_16113104_3 - 0.064 13.3 2.1 0.13 12.3 2.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system Guanylin PF02058.13 NONDRET014647.1_16112118_1 - 1.4e-15 57.4 0.0 2.4e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Guanylin precursor LAT PF15234.4 NONDRET014647.1_16112118_1 - 0.031 13.9 0.4 0.043 13.4 0.4 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells Guanylin PF02058.13 NONDRET014647.1_16112118_2 - 0.00015 22.1 1.5 0.00015 22.1 1.5 1.8 2 0 0 2 2 2 1 Guanylin precursor Apo-CII PF05355.9 NONDRET014696.1_16112118_3 - 1.1e-09 38.2 0.6 1.5e-09 37.7 0.6 1.2 1 0 0 1 1 1 1 Apolipoprotein C-II FixQ PF05545.9 NONDRET014730.1_16112102_1 - 0.46 10.4 4.1 0.92 9.4 4.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ FliD_N PF02465.16 NONDRET014730.1_16112102_3 - 0.089 13.4 0.1 0.15 12.7 0.1 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF4662 PF15578.4 NONDRET014736.1_16112102_3 - 2.2e-05 24.2 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4662) Collagen PF01391.16 NONDRET014750.1_16112102_1 - 0.0002 20.9 2.5 0.087 12.5 0.3 2.5 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Collagen PF01391.16 NONDRET014750.1_16112102_3 - 0.0026 17.4 50.2 85 2.9 50.2 4.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DDE_Tnp_4 PF13359.4 NONDRET014753.1_16112102_2 - 7.4e-16 58.1 0.0 3.4e-15 55.9 0.0 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease MAP7 PF05672.9 NONDRET014754.1_16112102_1 - 8e-10 38.5 11.4 1.2e-09 37.9 11.4 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family DUF3880 PF12996.5 NONDRET014757.1_16111104_1 - 0.14 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) Ten1_2 PF15490.4 NONDRET014759.1_16112118_1 - 3.4e-20 71.8 0.0 4.6e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Ten1_2 PF15490.4 NONDRET014759.1_16112118_2 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit DUF1582 PF07621.9 NONDRET014779.1_16111104_3 - 0.46 10.3 0.0 0.46 10.3 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1582) RVT_1 PF00078.25 NONDRET014794.1_16117102_1 - 1.5e-06 27.8 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipase_GDSL_2 PF13472.4 NONDRET014794.1_16117102_2 - 3.3e-14 53.5 0.0 7.4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Exo_endo_phos_2 PF14529.4 NONDRET014794.1_16117102_2 - 4.7e-05 23.1 0.2 0.00021 21.0 0.1 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Lipase_GDSL PF00657.20 NONDRET014794.1_16117102_2 - 0.00013 21.8 0.0 0.00038 20.4 0.0 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Exo_endo_phos PF03372.21 NONDRET014794.1_16117102_2 - 0.00032 20.8 0.0 0.00061 19.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OSK PF17182.2 NONDRET014794.1_16117102_2 - 0.033 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 OSK domain DDE_Tnp_4 PF13359.4 NONDRET014833.1_16111102_3 - 0.048 13.2 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Ras PF00071.20 058274.3_07622001_1 - 1.5e-62 209.9 0.3 1.7e-62 209.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 058274.3_07622001_1 - 2.1e-35 121.4 0.1 3.2e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 058274.3_07622001_1 - 1.3e-12 47.4 0.1 1.7e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 058274.3_07622001_1 - 1.5e-07 31.3 0.1 2.4e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 058274.3_07622001_1 - 4.3e-05 23.0 0.2 0.00019 20.9 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 058274.3_07622001_1 - 0.00011 22.0 0.3 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.4 058274.3_07622001_1 - 0.00013 22.1 0.0 0.0022 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.10 058274.3_07622001_1 - 0.00063 19.0 0.1 0.0009 18.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.8 058274.3_07622001_1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.4 058274.3_07622001_1 - 0.0076 16.5 0.1 0.011 15.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.16 058274.3_07622001_1 - 0.016 14.6 0.2 0.038 13.4 0.2 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.4 058274.3_07622001_1 - 0.016 15.1 0.1 0.04 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.25 058274.3_07622001_1 - 0.02 15.2 0.1 0.037 14.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.7 058274.3_07622001_1 - 0.036 13.7 0.0 0.098 12.3 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FAD-SLDH PF12318.6 058274.3_07622001_1 - 0.037 14.0 0.1 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_24 PF13479.4 058274.3_07622001_1 - 0.075 12.6 0.1 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.4 058274.3_07622001_1 - 0.094 12.4 0.2 0.22 11.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TniB PF05621.9 058274.3_07622001_1 - 0.12 11.4 0.0 0.3 10.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.12 058274.3_07622001_1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RRM_1 PF00076.20 058323.4_07624001_1 - 7.3e-05 22.4 0.0 0.00023 20.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox PF00046.27 001306308.1_07627001_1 - 3e-46 154.9 24.0 8.6e-17 60.6 2.6 4.5 4 0 0 4 4 4 3 Homeobox domain Homeobox_KN PF05920.9 001306308.1_07627001_1 - 1.8e-09 37.2 3.9 0.00053 19.7 0.0 4.3 4 0 0 4 4 4 2 Homeobox KN domain zf-C2H2_2 PF12756.5 001306308.1_07627001_1 - 4e-07 30.2 21.0 0.012 15.8 0.3 6.3 5 1 1 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.4 001306308.1_07627001_1 - 6.2e-07 29.6 31.6 0.063 14.0 0.2 6.4 7 0 0 7 7 6 4 C2H2-type zinc finger zf-C2H2 PF00096.24 001306308.1_07627001_1 - 0.003 17.8 25.9 0.066 13.6 1.1 5.7 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-met PF12874.5 001306308.1_07627001_1 - 0.0048 17.1 0.5 0.0048 17.1 0.5 4.5 5 0 0 5 5 4 1 Zinc-finger of C2H2 type Homez PF11569.6 001306308.1_07627001_1 - 0.011 15.0 2.2 2.2 7.7 0.3 3.2 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez zf-DBF PF07535.10 001306308.1_07627001_1 - 0.017 15.1 0.2 0.017 15.1 0.2 2.5 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_jaz PF12171.6 001306308.1_07627001_1 - 0.023 14.9 0.2 0.023 14.9 0.2 4.3 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding MerR_1 PF13411.4 001306308.1_07627001_1 - 0.13 12.2 0.1 2.6 8.1 0.0 2.9 3 0 0 3 3 3 0 MerR HTH family regulatory protein Evr1_Alr PF04777.11 001306308.1_07627001_1 - 1.4 9.3 14.5 4.1 7.9 1.1 4.0 3 0 0 3 3 3 0 Erv1 / Alr family zf-C2HE PF16278.3 001306308.1_07627001_1 - 1.4 9.3 10.9 6.6 7.2 0.1 4.6 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.14 001306308.1_07627001_1 - 1.6 8.9 14.8 0.8 9.8 2.9 4.3 4 0 0 4 4 4 0 AN1-like Zinc finger zf-BED PF02892.13 001306308.1_07627001_1 - 1.8 8.6 10.6 5 7.1 0.1 5.2 6 0 0 6 6 6 0 BED zinc finger HypA PF01155.17 001306308.1_07627001_1 - 5.8 6.8 12.4 5 7.0 1.7 4.0 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SF3a60_bindingd PF12108.6 001306263.1_07621001_2 - 0.013 15.2 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain I_LWEQ PF01608.15 001306510.1_07629001_1 - 1.3e-44 151.9 9.9 1.3e-44 151.9 9.9 11.6 8 2 3 12 12 12 7 I/LWEQ domain VBS PF08913.8 001306510.1_07629001_1 - 2.7e-18 66.5 52.3 1.9e-17 63.8 0.7 8.7 8 2 2 10 10 10 5 Vinculin Binding Site SLT PF01464.18 001306510.1_07629001_1 - 0.0025 17.3 1.2 0.017 14.6 0.1 3.0 4 0 0 4 4 4 1 Transglycosylase SLT domain RNA_polI_A14 PF08203.9 001306510.1_07629001_1 - 4.5 7.9 9.8 3.4 8.3 0.9 4.8 4 0 0 4 4 4 0 Yeast RNA polymerase I subunit RPA14 Vinculin PF01044.17 058607.4_07625001_1 - 3.5e-76 257.2 10.5 1e-40 139.7 2.1 3.0 1 1 1 3 3 3 3 Vinculin family DUF1003 PF06210.9 058607.4_07625001_1 - 0.04 13.9 1.1 0.22 11.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) GTP_EFTU PF00009.25 058937.4_07623001_1 - 1.6e-49 168.0 0.9 2.5e-49 167.3 0.9 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.23 058937.4_07623001_1 - 5.4e-14 52.2 4.0 1.3e-13 51.0 4.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.15 058937.4_07623001_1 - 1.4e-06 28.4 0.0 2.2e-05 24.6 0.0 2.8 2 2 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.21 058937.4_07623001_1 - 0.00031 20.7 1.7 0.00041 20.3 0.2 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.17 058937.4_07623001_1 - 0.011 15.3 1.5 0.035 13.6 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.14 058937.4_07623001_1 - 0.031 14.1 1.1 0.076 12.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF258 DUF1732 PF08340.9 001262693.1_07623001_2 - 0.011 15.6 0.8 0.028 14.3 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) E3_UbLigase_R4 PF13764.4 001318271.1_07629001_1 - 6.1e-207 689.4 0.2 6.1e-207 689.4 0.2 3.3 3 1 0 3 3 3 1 E3 ubiquitin-protein ligase UBR4 DNA_PPF PF02916.13 001318271.1_07629001_1 - 1.9e-33 115.1 0.3 1.9e-33 115.1 0.3 2.7 2 0 0 2 2 2 1 DNA polymerase processivity factor zf-UBR PF02207.18 001318271.1_07629001_1 - 3.7e-08 33.3 13.6 3.7e-08 33.3 13.6 3.4 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) DUF383 PF04063.12 001318271.1_07629001_1 - 0.07 12.7 2.0 1.4 8.5 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF383) Cnd1 PF12717.5 001318271.1_07629001_1 - 1.1 9.1 7.2 4.8 7.0 0.0 4.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ACBP PF00887.17 059011.5_07621001_1 - 1.7e-29 101.7 0.3 2e-29 101.5 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein MG1 PF11974.6 059011.5_07621001_1 - 0.06 13.2 0.1 0.073 12.9 0.1 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain TTR-52 PF01060.21 059011.5_07621001_1 - 0.088 13.4 0.1 0.2 12.2 0.0 1.5 1 1 0 2 2 2 0 Transthyretin-like family Pkinase_Tyr PF07714.15 170855.4_07625001_1 - 8.6e-83 277.4 0.0 1.3e-82 276.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 170855.4_07625001_1 - 6.7e-45 153.4 0.0 1.9e-44 151.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Focal_AT PF03623.11 170855.4_07625001_1 - 3.4e-11 43.1 1.8 7.9e-11 41.9 1.8 1.6 1 0 0 1 1 1 1 Focal adhesion targeting region Kinase-like PF14531.4 170855.4_07625001_1 - 0.00092 18.5 0.0 0.018 14.2 0.0 2.4 2 1 1 3 3 3 1 Kinase-like CENP-B_dimeris PF09026.8 170855.4_07625001_1 - 0.072 13.4 1.3 0.15 12.3 1.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain APH PF01636.21 170855.4_07625001_1 - 0.13 12.0 0.2 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family IKI3 PF04762.10 059123.5_07628001_1 - 5.2e-97 325.8 16.6 9.4e-76 255.5 8.6 2.3 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.5 059123.5_07628001_1 - 4e-06 26.9 4.6 0.3 11.3 0.2 6.2 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain MRP-L47 PF06984.11 001047168.1_07622001_1 - 6.4e-31 106.2 0.7 1.3e-30 105.2 0.7 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.21 001047168.1_07622001_1 - 0.017 14.9 0.3 0.037 13.9 0.3 1.6 1 0 0 1 1 1 0 Ribosomal L29 protein LLGL PF08366.11 001129023.1_07627001_1 - 6.5e-25 87.4 0.0 1.5e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 LLGL2 ANAPC4_WD40 PF12894.5 001129023.1_07627001_1 - 1.3e-07 31.7 0.5 0.15 12.2 0.0 5.1 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.8 001129023.1_07627001_1 - 3.4e-07 29.2 0.0 0.0038 15.8 0.1 3.3 2 2 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.30 001129023.1_07627001_1 - 6.7e-07 29.8 6.0 1.1 10.1 0.0 7.0 7 1 0 7 7 7 2 WD domain, G-beta repeat RAB3GAP2_N PF14655.4 001129023.1_07627001_1 - 0.00012 21.3 2.1 3.4 6.6 0.1 4.8 4 1 1 5 5 5 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.3 001129023.1_07627001_1 - 0.0064 15.7 0.2 0.054 12.7 0.0 2.4 3 0 0 3 3 3 1 WD40-like domain Hydrolase_4 PF12146.6 001129023.1_07627001_1 - 0.029 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Synaptobrevin PF00957.19 001129023.1_07627001_1 - 0.05 13.3 0.7 0.11 12.2 0.7 1.5 1 0 0 1 1 1 0 Synaptobrevin DIM1 PF02966.14 001129023.1_07627001_1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Mitosis protein DIM1 Homeobox PF00046.27 059345.4_07622001_1 - 3.9e-22 77.7 2.2 5.9e-22 77.1 2.2 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 059345.4_07622001_1 - 0.0085 15.8 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.6 059345.4_07622001_1 - 0.02 14.2 0.3 0.19 11.1 0.0 2.3 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez DUF4611 PF15387.4 059345.4_07622001_1 - 3.2 7.9 10.3 15 5.7 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.8 059345.4_07622001_1 - 5.1 7.4 10.2 0.98 9.7 2.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.4 059345.4_07622001_1 - 5.3 7.4 7.9 19 5.7 0.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTPRCAP PF15713.3 059345.4_07622001_1 - 7 6.8 10.6 16 5.6 6.3 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Fumble PF03630.12 170879.6_07623001_1 - 4.6e-88 295.4 0.1 6e-88 295.1 0.1 1.1 1 0 0 1 1 1 1 Fumble zf-C2H2 PF00096.24 059539.5_07625001_1 - 0.64 10.5 3.3 1.3 9.5 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Nse4_C PF08743.8 059539.5_07625001_1 - 3.4 7.8 8.1 1.1 9.5 2.8 3.0 2 0 0 2 2 2 0 Nse4 C-terminal DUF21 PF01595.18 059639.3_07623001_1 - 8.5e-37 126.4 1.7 1.2e-36 125.9 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.26 059639.3_07623001_1 - 0.00013 22.2 0.1 0.62 10.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain ASC PF00858.22 059829.4_07624001_1 - 3.1e-93 312.8 7.6 4.1e-93 312.4 7.6 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel IncA PF04156.12 059829.4_07624001_1 - 0.0067 16.1 0.4 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 IncA protein SieB PF14163.4 059829.4_07624001_1 - 0.02 14.3 1.6 0.85 9.0 0.3 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B Gemini_AL1_M PF08283.9 059829.4_07624001_1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Geminivirus rep protein central domain Sigma_reg_N PF13800.4 059829.4_07624001_1 - 0.85 9.8 3.2 14 5.9 0.9 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal UPF0183 PF03676.12 171841.6_07623001_1 - 5.8e-130 433.9 1.1 6.7e-130 433.7 1.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) CK_II_beta PF01214.16 059854.4_07622001_1 - 3.1e-82 274.7 0.0 3.6e-82 274.5 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HCO3_cotransp PF00955.19 001136305.2_07628001_1 - 3.7e-217 722.1 12.7 5.6e-217 721.5 12.7 1.3 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.11 001136305.2_07628001_1 - 6.8e-101 337.5 0.0 7.6e-68 229.1 0.0 2.4 1 1 1 2 2 2 2 Band 3 cytoplasmic domain LSM14 PF12701.5 059927.5_07624001_1 - 3.3e-08 33.4 0.3 1.7e-07 31.1 0.3 2.2 1 1 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.4 059927.5_07624001_1 - 0.002 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Mu-transpos_C PF09299.9 059927.5_07624001_1 - 0.16 11.8 0.1 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Mu transposase, C-terminal FDF PF09532.8 059927.5_07624001_1 - 5.9 7.7 8.7 0.23 12.2 1.9 2.1 2 0 0 2 2 2 0 FDF domain FYVE PF01363.19 059964.3_07627001_2 - 0.00048 20.1 0.4 0.0011 18.9 0.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Peptidase_A22B PF04258.11 001025852.4_07624001_1 - 2.2e-81 273.4 15.8 3.5e-81 272.7 15.8 1.3 1 0 0 1 1 1 1 Signal peptide peptidase Presenilin PF01080.15 001025852.4_07624001_1 - 0.013 14.1 0.6 0.013 14.1 0.6 2.7 2 1 0 2 2 2 0 Presenilin PINIT PF14324.4 060041.3_07625001_1 - 6e-24 84.9 0.4 6e-24 84.9 0.4 2.8 4 1 1 5 5 5 1 PINIT domain zf-MIZ PF02891.18 060041.3_07625001_1 - 4.5e-18 64.6 6.1 9.8e-18 63.5 6.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.6 060041.3_07625001_1 - 1.3e-05 24.7 2.2 3.5e-05 23.4 2.2 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PHD_4 PF16866.3 060041.3_07625001_1 - 0.14 12.2 3.9 0.54 10.3 3.9 2.0 1 0 0 1 1 1 0 PHD-finger PHD PF00628.27 060041.3_07625001_1 - 0.16 11.8 6.1 0.4 10.5 6.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.23 060041.3_07625001_1 - 0.83 9.5 7.0 1.6 8.5 7.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 060041.3_07625001_1 - 4.2 7.2 8.7 9 6.1 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lectin_C PF00059.19 060047.4_07622001_1 - 2.6e-12 47.3 0.3 4.5e-12 46.5 0.3 1.4 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.10 060047.4_07622001_1 - 0.0046 16.1 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein PhoLip_ATPase_C PF16212.3 001026286.3_07627001_1 - 1.7e-48 165.4 23.7 1.7e-48 165.4 23.7 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.3 001026286.3_07627001_1 - 2.6e-17 62.2 4.1 6.1e-17 61.0 4.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.18 001026286.3_07627001_1 - 2e-15 56.6 0.0 2e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.24 001026286.3_07627001_1 - 1.9e-14 54.3 0.2 7.9e-07 29.4 0.1 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.4 001026286.3_07627001_1 - 1.5e-10 40.9 0.0 2.8e-09 36.8 0.0 2.7 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.10 001026286.3_07627001_1 - 0.0019 17.8 0.0 0.0057 16.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AbfB PF05270.11 001026286.3_07627001_1 - 0.053 13.4 0.4 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) domain Skp1 PF01466.17 060112.5_07622001_1 - 8.3e-31 105.7 0.8 1.5e-30 104.9 0.8 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.13 060112.5_07622001_1 - 1.3e-19 69.9 0.2 3.2e-19 68.7 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.29 060112.5_07622001_1 - 0.081 13.0 0.3 18 5.5 0.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain IPK PF03770.14 060118.4_07622001_1 - 9.8e-47 159.2 0.0 1.5e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase SMN PF06003.10 060124.4_07622001_1 - 1.9e-20 73.1 13.7 1.7e-10 40.5 1.9 3.0 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) ATE_C PF04377.13 001348618.1_07623001_1 - 8.8e-47 159.0 2.9 8.8e-47 159.0 2.9 1.6 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.11 001348618.1_07623001_1 - 1.6e-16 60.3 2.4 2.4e-16 59.7 0.5 2.2 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.5 001348618.1_07623001_1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RNase_H PF00075.22 060180.3_07621001_1 - 7.2e-28 97.4 0.3 8.7e-28 97.2 0.3 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.4 060180.3_07621001_1 - 0.00058 19.4 0.0 0.011 15.2 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase-like DNA_primase_lrg PF04104.12 001264994.1_07622001_1 - 1.6e-81 273.5 0.3 1.8e-81 273.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit SLT_L PF14718.4 001264994.1_07622001_1 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Soluble lytic murein transglycosylase L domain ThiF PF00899.19 001306225.1_07624001_1 - 2.7e-66 223.3 0.1 3.8e-66 222.8 0.1 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.4 001306225.1_07624001_1 - 1.3e-21 76.9 0.1 2.6e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.7 001306225.1_07624001_1 - 1.2e-05 25.2 9.9 0.0011 18.8 0.1 3.1 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.4 001306225.1_07624001_1 - 3.5e-05 24.1 0.0 9.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.18 001306225.1_07624001_1 - 0.00065 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.22 001306225.1_07624001_1 - 0.003 17.9 0.5 0.0096 16.2 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox PF00070.25 001306225.1_07624001_1 - 0.0033 17.8 0.1 0.0094 16.4 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.12 001306225.1_07624001_1 - 0.036 13.5 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.16 001306225.1_07624001_1 - 0.052 13.7 0.6 0.6 10.2 0.6 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Flavi_NS2B PF01002.17 001306225.1_07624001_1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Esterase PF00756.18 060970.6_07622001_1 - 1e-48 166.1 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.5 060970.6_07622001_1 - 8.1e-06 24.8 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.6 060970.6_07622001_1 - 6.9e-05 22.1 0.0 9.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.19 060970.6_07622001_1 - 0.0015 17.9 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.9 060970.6_07622001_1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_1 PF00561.18 060970.6_07622001_1 - 0.015 14.8 0.1 0.029 13.9 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.7 060970.6_07622001_1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase UPF0227 PF05728.10 060970.6_07622001_1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.14 060970.6_07622001_1 - 0.087 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3251 PF11622.6 049899.1_07621120_1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Sigma54_AID PF00309.18 049924.1_07621120_2 - 0.75 9.6 6.0 14 5.5 0.2 3.2 1 1 1 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) KRTAP PF11759.6 049931.1_07621120_2 - 0.0044 17.4 28.7 4.8 7.7 28.7 2.2 1 1 0 1 1 1 1 Keratin-associated matrix Keratin_2_head PF16208.3 049931.1_07621120_2 - 0.4 10.7 29.5 20 5.2 29.5 2.1 1 1 0 1 1 1 0 Keratin type II head OMP_b-brl PF13505.4 049931.1_07621120_2 - 1.2 9.1 7.9 0.49 10.4 1.8 2.2 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain SH2 PF00017.22 132554.1_07629120_2 - 3.7e-17 62.0 0.1 6.8e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 SH2 domain PID PF00640.21 132554.1_07629120_2 - 0.00036 20.4 0.1 0.00065 19.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) MFS_1 PF07690.14 131353.1_07624120_2 - 2.4e-42 145.0 33.4 7.6e-42 143.4 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 131353.1_07624120_2 - 2.2e-06 26.7 30.5 3.6e-06 26.0 30.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter AA_permease_2 PF13520.4 131780.1_07624120_1 - 7.8e-28 97.3 26.6 9.4e-28 97.1 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.19 131780.1_07624120_1 - 1.2e-09 37.2 20.1 1.5e-09 36.9 20.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.4 131780.1_07624120_2 - 2.2e-09 36.5 13.3 2.8e-09 36.2 11.7 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.19 131780.1_07624120_2 - 0.00045 18.8 15.4 0.0018 16.8 15.4 1.8 1 1 0 1 1 1 1 Amino acid permease TPR_MLP1_2 PF07926.10 131364.1_07621120_3 - 0.0011 19.0 0.5 0.0012 18.8 0.5 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF3972 PF13118.4 131364.1_07621120_3 - 0.028 14.7 0.1 0.037 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) RIO1 PF01163.20 132555.1_07625120_1 - 4.9e-36 124.0 0.0 1.1e-35 122.8 0.0 1.6 1 0 0 1 1 1 1 RIO1 family RIO1 PF01163.20 132555.1_07625120_3 - 3.9e-33 114.5 0.1 3.9e-33 114.5 0.1 1.9 2 0 0 2 2 2 1 RIO1 family CDC45 PF02724.12 132555.1_07625120_3 - 0.0047 15.2 8.9 0.0054 15.0 8.9 1.1 1 0 0 1 1 1 1 CDC45-like protein CAP_N PF01213.17 131381.1_07623120_1 - 8.4e-71 238.9 0.0 1.1e-70 238.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal NeA_P2 PF12312.6 131381.1_07623120_1 - 0.25 10.6 1.2 0.38 10.0 1.2 1.2 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein CAP_C PF08603.9 131381.1_07623120_2 - 3.5e-55 185.8 6.2 4.9e-55 185.3 6.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.10 131381.1_07623120_2 - 0.00019 21.0 4.8 0.051 13.2 0.3 2.5 1 1 0 2 2 2 2 Tubulin binding cofactor C CH PF00307.29 136357.1_07624120_3 - 4.8e-09 36.2 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Integrin_alpha PF00357.18 136357.1_07624120_3 - 0.83 9.7 4.7 0.59 10.1 0.2 2.5 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region KfrA_N PF11740.6 050183.1_07621120_3 - 0.1 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term tRNA-synt_2 PF00152.18 002344.1_07622120_1 - 1.4e-33 116.2 0.0 2.4e-33 115.5 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) VAD1-2 PF15310.4 002344.1_07622120_1 - 0.25 11.1 3.6 0.35 10.6 3.6 1.2 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Dodecin PF07311.10 002344.1_07622120_1 - 5.8 7.1 6.6 1.3 9.2 0.5 2.4 2 1 1 3 3 3 0 Dodecin Na_K-ATPase PF00287.16 136361.1_07625120_2 - 1.4e-79 267.1 0.3 1.4e-79 267.1 0.3 1.8 2 0 0 2 2 2 1 Sodium / potassium ATPase beta chain MFMR_assoc PF16596.3 050472.1_07621120_2 - 0.092 13.1 0.1 0.11 12.9 0.1 1.0 1 0 0 1 1 1 0 Disordered region downstream of MFMR AAA_12 PF13087.4 132564.1_07624120_2 - 4.1e-33 114.5 0.1 6.1e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.16 132564.1_07624120_2 - 0.0019 17.8 0.1 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.4 132564.1_07624120_2 - 0.002 17.7 0.1 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MerR_2 PF13591.4 132564.1_07624120_2 - 0.028 14.1 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein AAA_11 PF13086.4 132564.1_07624120_3 - 1.2e-35 123.4 1.4 1.6e-22 80.4 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.4 132564.1_07624120_3 - 1.3e-12 47.7 0.0 7.5e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.4 132564.1_07624120_3 - 1.4e-11 44.8 0.3 3.4e-11 43.5 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.4 132564.1_07624120_3 - 6.8e-11 42.0 0.9 1.2e-10 41.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.13 132564.1_07624120_3 - 1e-06 28.7 0.4 3.4e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.16 132564.1_07624120_3 - 1.2e-06 28.3 0.0 0.00088 18.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.12 132564.1_07624120_3 - 9.3e-06 25.5 3.2 0.00025 20.8 1.0 2.6 2 1 0 2 2 2 1 Helicase Flavi_DEAD PF07652.12 132564.1_07624120_3 - 1.2e-05 25.2 0.4 4.2e-05 23.4 0.2 1.8 2 0 0 2 2 2 1 Flavivirus DEAD domain PIF1 PF05970.12 132564.1_07624120_3 - 0.00011 21.4 0.0 0.00085 18.5 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.7 132564.1_07624120_3 - 0.00012 21.3 0.2 0.01 15.0 0.2 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.19 132564.1_07624120_3 - 0.0071 15.8 5.2 0.46 9.8 3.5 2.5 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_22 PF13401.4 132564.1_07624120_3 - 0.0086 16.2 0.1 0.1 12.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.20 132564.1_07624120_3 - 0.014 15.6 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.16 132564.1_07624120_3 - 0.021 14.6 0.1 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.27 132564.1_07624120_3 - 0.027 14.8 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.20 132564.1_07624120_3 - 0.033 13.7 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.4 132564.1_07624120_3 - 0.049 13.9 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.23 132564.1_07624120_3 - 0.11 12.0 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Thioredoxin_8 PF13905.4 003150.1_07626120_1 - 5.3e-23 81.0 1.9 1.2e-22 79.9 0.1 2.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin PF00085.18 003150.1_07626120_1 - 8.7e-06 25.5 0.4 4.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin CENP-B_dimeris PF09026.8 050711.1_07624120_1 - 0.21 11.8 5.3 0.4 11.0 5.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PB1 PF00564.22 050711.1_07624120_2 - 6.4e-11 41.9 0.2 1.2e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 PB1 domain Anillin_N PF16018.3 050711.1_07624120_2 - 0.45 11.0 2.5 6.4 7.3 0.9 2.5 2 0 0 2 2 2 0 Anillin N-terminus ADP_PFK_GK PF04587.13 061256.4_07624001_1 - 2.2e-126 421.7 0.0 2.5e-126 421.5 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF2561 PF10812.6 061278.3_07623001_1 - 0.0041 17.1 0.1 0.0041 17.1 0.1 2.7 2 1 2 4 4 4 1 Protein of unknown function (DUF2561) Biopterin_H PF00351.19 001267080.1_07624001_1 - 4.4e-148 492.6 0.1 5.9e-148 492.2 0.1 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase EF-hand_1 PF00036.30 061311.4_07623001_1 - 2e-31 105.1 30.9 0.0022 17.3 0.0 11.3 11 0 0 11 11 11 11 EF hand EF-hand_5 PF13202.4 061311.4_07623001_1 - 3.9e-30 101.9 34.8 0.00089 18.5 0.3 11.4 11 0 0 11 11 11 10 EF hand EF-hand_7 PF13499.4 061311.4_07623001_1 - 4e-27 94.3 22.2 1.5e-06 28.5 0.3 8.0 5 1 5 10 10 10 8 EF-hand domain pair EF-hand_6 PF13405.4 061311.4_07623001_1 - 9.1e-26 87.4 26.0 0.019 14.8 0.1 11.2 11 0 0 11 11 11 10 EF-hand domain EF-hand_8 PF13833.4 061311.4_07623001_1 - 1e-13 50.6 31.2 0.0024 17.4 0.2 10.0 9 1 1 10 10 10 6 EF-hand domain pair SPARC_Ca_bdg PF10591.7 061311.4_07623001_1 - 6.9e-13 48.8 6.9 8.9e-06 25.9 0.1 6.2 2 2 4 7 7 7 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.4 061311.4_07623001_1 - 3.6e-07 29.8 0.6 0.75 9.6 0.0 6.4 7 0 0 7 7 7 2 EF hand DUF2774 PF11242.6 061311.4_07623001_1 - 0.033 14.2 0.0 0.61 10.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2774) 7TM_GPCR_Sri PF10327.7 061381.2_07623001_1 - 9.8e-102 340.1 24.0 1.1e-101 339.9 24.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Srh PF10318.7 061381.2_07623001_1 - 5.1e-24 84.7 26.9 6e-24 84.5 26.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srd PF10317.7 061381.2_07623001_1 - 7.1e-05 22.0 24.6 0.00011 21.4 24.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd DUF2269 PF10027.7 061381.2_07623001_1 - 0.019 14.9 1.8 0.055 13.4 1.3 2.1 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF3557 PF12078.6 061470.4_07622001_1 - 1.2e-33 116.0 0.3 2.3e-33 115.1 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3557) F-box PF00646.31 061470.4_07622001_1 - 0.047 13.5 1.5 0.14 11.9 0.2 2.2 2 0 0 2 2 2 0 F-box domain His_Phos_2 PF00328.20 061510.1_07623001_1 - 2.8e-30 105.8 0.0 8.1e-28 97.7 0.0 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FBA_2 PF07735.15 061635.1_07622001_1 - 1.3e-19 69.9 5.0 1.3e-19 69.9 5.0 2.3 2 1 1 3 3 3 1 F-box associated F-box PF00646.31 061635.1_07622001_1 - 0.0052 16.5 0.1 0.018 14.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain Recep_L_domain PF01030.22 061662.1_07624001_1 - 1.2e-35 121.8 15.4 3.9e-19 68.7 0.3 3.3 3 0 0 3 3 3 3 Receptor L domain AsmA_1 PF13109.4 061662.1_07624001_1 - 0.034 13.5 2.8 2.5 7.4 0.1 2.7 3 0 0 3 3 3 0 AsmA-like C-terminal region FTH PF01827.25 061683.2_07622001_1 - 3.1e-38 130.7 3.2 5.5e-38 129.9 3.2 1.4 1 0 0 1 1 1 1 FTH domain F-box PF00646.31 061683.2_07622001_1 - 4.1e-08 32.8 0.1 1.3e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 F-box domain MATH PF00917.24 001267117.1_07621001_1 - 2.8e-44 149.7 0.7 3.4e-44 149.4 0.7 1.1 1 0 0 1 1 1 1 MATH domain PAT1 PF09770.7 061877.6_07624001_1 - 7.8 4.5 26.7 9.8 4.2 26.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAP PF00188.24 062095.4_07622001_1 - 2.2e-20 73.6 3.1 2.2e-20 73.6 3.1 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family BTB PF00651.29 182266.2_07622001_1 - 2.4e-19 69.4 0.2 6e-19 68.2 0.2 1.7 1 0 0 1 1 1 1 BTB/POZ domain 7TM_GPCR_Srx PF10328.7 062216.2_07622001_1 - 1.8e-65 220.8 30.7 2.3e-65 220.5 30.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Copine PF07002.14 062336.4_07627001_1 - 1.2e-60 204.5 0.0 2.5e-60 203.5 0.0 1.6 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.7 062336.4_07627001_1 - 3.9e-07 30.3 0.0 1.3e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 vWA found in TerF C terminus YtxH PF12732.5 062336.4_07627001_1 - 0.036 14.5 2.9 6.2 7.3 0.0 3.5 2 1 1 3 3 3 0 YtxH-like protein SAS4 PF15460.4 062336.4_07627001_1 - 0.23 11.5 3.4 1.6 8.8 0.4 3.2 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 COG5 PF10392.7 062336.4_07627001_1 - 1.5 8.8 5.9 0.32 11.0 0.2 2.7 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF3140 PF11338.6 062336.4_07627001_1 - 9.3 6.6 6.8 2.8 8.3 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) Pkinase_Tyr PF07714.15 062406.3_07627001_1 - 3.3e-83 278.8 0.0 6e-83 278.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 062406.3_07627001_1 - 5.2e-44 150.5 0.0 1.4e-43 149.0 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Ephrin_lbd PF01404.17 062406.3_07627001_1 - 4.7e-37 127.6 1.8 7.8e-37 126.9 1.8 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain EphA2_TM PF14575.4 062406.3_07627001_1 - 7.6e-23 81.0 0.0 2.1e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain fn3 PF00041.19 062406.3_07627001_1 - 1.6e-19 69.9 1.0 1.1e-09 38.4 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.3 062406.3_07627001_1 - 7.9e-06 26.2 0.1 0.25 11.8 0.1 3.2 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Ephrin_rec_like PF07699.11 062406.3_07627001_1 - 0.001 18.6 9.2 0.001 18.6 9.2 2.2 2 1 0 2 2 2 1 Putative ephrin-receptor like TMEM154 PF15102.4 062406.3_07627001_1 - 0.025 14.4 0.2 0.061 13.1 0.2 1.6 1 0 0 1 1 1 0 TMEM154 protein family Kdo PF06293.12 062406.3_07627001_1 - 0.028 13.6 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 062406.3_07627001_1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4366 PF14283.4 062406.3_07627001_1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SAM_2 PF07647.15 062406.3_07627001_1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PrgH PF09480.8 062406.3_07627001_1 - 0.16 11.0 0.1 0.84 8.7 0.0 1.9 2 0 0 2 2 2 0 Type III secretion system protein PrgH-EprH (PrgH) COX2_TM PF02790.13 062406.3_07627001_1 - 0.21 11.6 1.8 0.51 10.4 0.2 2.4 2 1 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain EGF_MSP1_1 PF12946.5 062406.3_07627001_1 - 0.36 10.8 4.4 1.7 8.6 0.2 2.6 2 0 0 2 2 2 0 MSP1 EGF domain 1 AhpC-TSA PF00578.19 001129132.2_07622001_1 - 2.8e-38 130.5 0.0 7.1e-38 129.2 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.8 001129132.2_07622001_1 - 6.9e-15 54.9 0.0 1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 001129132.2_07622001_1 - 2.9e-12 46.1 0.1 6.3e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Filament PF00038.19 062732.5_07624001_1 - 2.9e-50 171.5 35.0 4e-50 171.0 35.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein TSC22 PF01166.16 062732.5_07624001_1 - 0.0017 18.5 11.1 0.0092 16.1 0.6 4.4 4 0 0 4 4 4 1 TSC-22/dip/bun family DUF4407 PF14362.4 062732.5_07624001_1 - 0.0023 17.2 22.8 0.072 12.3 5.1 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4407) DUF972 PF06156.11 062732.5_07624001_1 - 0.0026 18.2 25.1 0.37 11.3 3.0 5.1 2 2 2 4 4 4 2 Protein of unknown function (DUF972) Fez1 PF06818.13 062732.5_07624001_1 - 0.0096 16.3 2.4 0.0096 16.3 2.4 3.1 1 1 3 4 4 4 2 Fez1 TolA_bind_tri PF16331.3 062732.5_07624001_1 - 0.012 15.5 1.8 0.012 15.5 1.8 4.6 4 1 0 4 4 4 0 TolA binding protein trimerisation TPR_MLP1_2 PF07926.10 062732.5_07624001_1 - 0.014 15.3 7.5 0.014 15.3 7.5 4.7 2 1 3 5 5 4 0 TPR/MLP1/MLP2-like protein UPF0184 PF03670.11 062732.5_07624001_1 - 0.04 14.2 9.4 0.35 11.1 0.1 3.6 3 1 1 4 4 3 0 Uncharacterised protein family (UPF0184) Laminin_II PF06009.10 062732.5_07624001_1 - 0.07 13.0 16.1 0.32 10.9 4.1 4.1 2 1 1 4 4 4 0 Laminin Domain II IncA PF04156.12 062732.5_07624001_1 - 0.1 12.2 39.5 0.017 14.8 2.8 3.6 1 1 4 5 5 5 0 IncA protein TBPIP PF07106.11 062732.5_07624001_1 - 0.11 12.1 22.8 0.26 10.9 6.7 4.7 1 1 4 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.6 062732.5_07624001_1 - 0.12 12.3 0.2 0.12 12.3 0.2 3.8 3 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding DASH_Dad4 PF08650.8 062732.5_07624001_1 - 0.16 11.8 3.7 0.39 10.6 0.5 2.8 3 0 0 3 3 2 0 DASH complex subunit Dad4 Reo_sigmaC PF04582.10 062732.5_07624001_1 - 0.2 10.9 4.9 0.21 10.8 0.6 2.6 1 1 0 3 3 3 0 Reovirus sigma C capsid protein Shugoshin_N PF07558.9 062732.5_07624001_1 - 0.29 10.9 5.9 1.6 8.5 0.9 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region BLOC1_2 PF10046.7 062732.5_07624001_1 - 0.38 11.0 8.9 3.6 7.8 0.2 3.6 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.8 062732.5_07624001_1 - 0.39 10.8 16.3 0.58 10.2 3.7 3.9 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF3251 PF11622.6 062732.5_07624001_1 - 0.59 9.6 3.0 0.47 10.0 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) Spc7 PF08317.9 062732.5_07624001_1 - 0.73 8.5 31.7 0.21 10.3 11.2 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein SOGA PF11365.6 062732.5_07624001_1 - 0.88 10.6 21.0 5.1 8.2 1.4 5.4 2 2 2 5 5 5 0 Protein SOGA CENP-F_leu_zip PF10473.7 062732.5_07624001_1 - 0.97 9.3 32.9 0.39 10.6 5.4 4.8 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc42p PF11544.6 062732.5_07624001_1 - 1 9.3 8.6 0.086 12.7 1.0 3.0 3 0 0 3 3 2 0 Spindle pole body component Spc42p Tropomyosin_1 PF12718.5 062732.5_07624001_1 - 2 8.4 20.4 1.3 9.0 5.7 3.6 2 1 1 3 3 3 0 Tropomyosin like DUF641 PF04859.10 062732.5_07624001_1 - 4.1 7.6 21.8 0.77 10.0 2.9 4.7 3 1 2 5 5 5 0 Plant protein of unknown function (DUF641) APG6 PF04111.10 062732.5_07624001_1 - 4.5 6.5 35.3 1.1 8.5 7.7 3.5 1 1 2 3 3 3 0 Autophagy protein Apg6 JIP_LZII PF16471.3 062732.5_07624001_1 - 5 7.2 16.3 2.6 8.2 0.1 4.7 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II DUF5082 PF16888.3 062732.5_07624001_1 - 6.8 6.9 19.3 0.25 11.6 3.7 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) RasGAP_C PF03836.13 062732.5_07624001_1 - 8.7 6.4 18.9 9.1 6.3 8.0 4.0 2 2 1 3 3 3 0 RasGAP C-terminus NADHdeh_related PF10125.7 062862.2_07622001_1 - 0.024 13.8 0.3 0.035 13.3 0.3 1.1 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein Anillin PF08174.9 062881.3_07627001_1 - 1.1e-24 87.3 0.1 3.1e-24 85.9 0.1 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.27 062881.3_07627001_1 - 2.9e-16 59.8 0.1 8.3e-16 58.3 0.1 1.9 1 0 0 1 1 1 1 PH domain AMP-binding PF00501.26 063049.3_07624001_1 - 3.3e-79 266.3 0.0 4e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 063049.3_07624001_1 - 8.8e-20 71.3 0.0 2.5e-19 69.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Spond_N PF06468.11 063072.7_07625001_1 - 5.4e-67 225.5 1.1 9e-67 224.8 1.1 1.4 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.17 063072.7_07625001_1 - 3.5e-48 161.5 59.7 7e-11 42.0 2.3 6.2 5 0 0 5 5 5 5 Thrombospondin type 1 domain Kunitz_BPTI PF00014.21 063072.7_07625001_1 - 1.7e-17 63.2 11.8 1.7e-17 63.2 11.8 3.4 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Reeler PF02014.14 063072.7_07625001_1 - 2.1e-17 64.0 0.2 4.7e-17 62.8 0.2 1.6 1 0 0 1 1 1 1 Reeler domain zf-C4 PF00105.16 001047301.2_07623001_1 - 3.8e-28 97.6 12.6 8e-28 96.6 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001047301.2_07623001_1 - 7.6e-09 35.3 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DEAD PF00270.27 001026814.3_07623001_1 - 2.7e-39 134.6 0.1 4.8e-39 133.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001026814.3_07623001_1 - 7.4e-26 90.6 0.5 6.9e-25 87.4 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.13 001026814.3_07623001_1 - 6.1e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.4 001026814.3_07623001_1 - 0.0028 16.9 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit dsrm PF00035.24 063489.5_07628001_1 - 7.8e-21 74.4 1.7 2.3e-09 37.7 0.3 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.29 063489.5_07628001_1 - 4.4e-18 65.5 0.1 1.2e-17 64.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.21 063489.5_07628001_1 - 2.1e-13 50.4 0.0 5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.14 063489.5_07628001_1 - 4.5e-09 36.3 0.1 9.9e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.27 063489.5_07628001_1 - 3.5e-08 33.3 0.0 7.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.11 063489.5_07628001_1 - 0.00047 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.4 063489.5_07628001_1 - 0.013 15.7 0.0 0.039 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.4 063489.5_07628001_1 - 0.053 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DND1_DSRM PF14709.5 063489.5_07628001_1 - 0.063 13.4 0.0 6 7.1 0.0 3.1 3 0 0 3 3 3 0 double strand RNA binding domain from DEAD END PROTEIN 1 ABC_tran PF00005.25 063489.5_07628001_1 - 0.13 12.7 0.2 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.4 063489.5_07628001_1 - 0.18 12.0 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.4 063489.5_07628001_1 - 0.36 10.7 1.7 2.4 8.1 0.1 3.1 3 1 0 3 3 3 0 AAA domain bZIP_1 PF00170.19 001027196.3_07622001_1 - 2.5e-06 27.3 14.1 3.8e-06 26.8 14.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.15 001027196.3_07622001_1 - 0.0005 20.4 11.6 0.00086 19.6 11.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.13 001027196.3_07622001_1 - 0.0035 17.2 15.0 0.0058 16.5 15.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF4763 PF15960.3 001027196.3_07622001_1 - 0.077 12.2 6.5 0.13 11.5 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Protamine_3 PF08188.9 001027196.3_07622001_2 - 0.021 14.9 0.6 0.071 13.2 0.6 1.9 1 0 0 1 1 1 0 Spermatozal protamine family 7TM_GPCR_Sra PF02117.14 063646.3_07622001_1 - 5.6e-147 488.7 30.0 6.3e-147 488.5 30.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sra 7TM_GPCR_Srab PF10292.7 063646.3_07622001_1 - 3.6e-09 35.9 24.2 4.4e-09 35.6 24.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srb PF02175.14 063646.3_07622001_1 - 0.018 14.7 24.4 0.033 13.8 24.4 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb Ion_trans PF00520.29 001047364.2_07623001_1 - 2.2e-41 141.6 16.1 2.8e-41 141.2 16.1 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001047364.2_07623001_1 - 1.1e-31 108.9 0.6 2.4e-31 107.8 0.6 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001047364.2_07623001_1 - 1.5e-12 47.1 4.5 1.5e-12 47.1 4.5 2.4 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.10 001047364.2_07623001_1 - 0.017 13.7 6.6 0.025 13.1 6.6 1.3 1 0 0 1 1 1 0 Polycystin cation channel Lig_chan PF00060.24 001047364.2_07623001_1 - 0.16 11.7 2.7 0.12 12.0 0.4 1.9 2 0 0 2 2 2 0 Ligand-gated ion channel DUF202 PF02656.13 001047364.2_07623001_1 - 0.4 11.0 7.9 20 5.6 4.3 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Corona_3 PF04694.10 001047364.2_07623001_3 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Coronavirus ORF3 protein zf-C2H2 PF00096.24 063774.6_07624001_1 - 2.3e-08 33.9 27.8 0.023 15.0 2.6 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 063774.6_07624001_1 - 2.9e-07 30.6 21.0 0.022 15.4 1.4 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.5 063774.6_07624001_1 - 4.3e-07 30.1 9.6 0.00056 20.1 1.8 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.4 063774.6_07624001_1 - 0.0018 17.8 0.8 0.0018 17.8 0.8 3.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-met PF12874.5 063774.6_07624001_1 - 0.0036 17.5 0.7 0.0036 17.5 0.7 4.8 4 1 0 4 4 4 1 Zinc-finger of C2H2 type DUF4729 PF15866.3 063774.6_07624001_1 - 0.0052 16.0 1.2 0.15 11.2 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4729) zf-C2H2_jaz PF12171.6 063774.6_07624001_1 - 0.013 15.6 0.3 0.013 15.6 0.3 5.5 4 1 1 5 5 5 0 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.3 063774.6_07624001_1 - 0.056 12.5 4.0 0.45 9.5 0.6 3.1 1 1 1 2 2 2 0 Putative actin-like family Yippee-Mis18 PF03226.12 063774.6_07624001_1 - 0.26 11.4 5.1 2.8 8.1 0.2 3.5 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3505 PF12013.6 063774.6_07624001_1 - 5.8 7.3 9.5 27 5.1 0.7 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF3505) CLP_protease PF00574.21 001267311.1_07622001_1 - 9.9e-79 263.3 0.0 1.2e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.14 001267311.1_07622001_1 - 0.092 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase GTP-bdg_M PF16360.3 001267311.1_07622001_1 - 0.11 13.0 0.0 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Gp_dh_C PF02800.18 063836.4_07623001_1 - 9e-71 236.4 0.0 1.9e-70 235.4 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 063836.4_07623001_1 - 7e-36 122.5 0.2 1.6e-35 121.4 0.2 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 063836.4_07623001_1 - 0.015 15.3 0.4 0.08 12.9 0.1 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.17 063836.4_07623001_1 - 0.098 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pept_tRNA_hydro PF01195.17 063836.4_07623001_1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase Homeobox PF00046.27 063925.4_07622001_1 - 4.5e-21 74.3 3.5 8.3e-21 73.4 3.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 063925.4_07622001_1 - 0.0044 16.8 0.1 0.012 15.3 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Sec10 PF07393.9 063925.4_07622001_1 - 0.0056 15.0 0.6 0.0062 14.9 0.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Homez PF11569.6 063925.4_07622001_1 - 0.015 14.7 0.2 0.05 12.9 0.2 1.9 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez TPR_19 PF14559.4 063925.4_07622001_1 - 0.041 14.3 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Auxin_canalis PF05703.9 063925.4_07622001_1 - 0.15 11.9 4.3 0.11 12.2 3.3 1.3 1 1 0 1 1 1 0 Auxin canalisation Gly-rich_Ago1 PF12764.5 063925.4_07622001_1 - 4.5 7.9 13.0 0.14 12.8 6.3 2.0 2 1 0 2 2 2 0 Glycine-rich region of argonaut Y_phosphatase PF00102.25 001306540.1_07629001_1 - 1.1e-154 512.7 0.1 4.2e-84 281.6 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.19 001306540.1_07629001_1 - 6.4e-89 292.3 30.4 4.3e-13 49.3 0.1 10.3 10 0 0 10 10 10 9 Fibronectin type III domain Ig_3 PF13927.4 001306540.1_07629001_1 - 1.7e-33 115.0 3.9 3.5e-11 43.4 0.0 6.4 6 0 0 6 6 6 3 Immunoglobulin domain I-set PF07679.14 001306540.1_07629001_1 - 3.1e-31 107.2 0.0 8.3e-14 51.3 0.0 4.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.4 001306540.1_07629001_1 - 1.3e-18 67.0 0.0 2.1e-05 24.7 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.3 001306540.1_07629001_1 - 4.8e-15 55.8 24.9 0.092 13.2 0.0 8.7 8 1 0 8 8 8 5 Purple acid Phosphatase, N-terminal domain ig PF00047.23 001306540.1_07629001_1 - 7.9e-14 51.5 0.1 0.0018 18.3 0.0 4.6 5 0 0 5 5 4 3 Immunoglobulin domain Interfer-bind PF09294.8 001306540.1_07629001_1 - 5.2e-07 29.8 3.6 1.3 9.3 0.1 6.8 7 1 0 7 7 7 2 Interferon-alpha/beta receptor, fibronectin type III C2-set_2 PF08205.10 001306540.1_07629001_1 - 1.8e-05 24.6 0.0 0.056 13.4 0.0 4.0 4 0 0 4 4 3 1 CD80-like C2-set immunoglobulin domain DSPc PF00782.18 001306540.1_07629001_1 - 2e-05 24.2 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.4 001306540.1_07629001_1 - 5.8e-05 23.1 0.1 0.046 13.7 0.0 2.8 2 0 0 2 2 2 2 Inositol hexakisphosphate PhoD_N PF16655.3 001306540.1_07629001_1 - 0.00039 20.7 0.8 9.2 6.8 0.1 4.7 4 0 0 4 4 4 1 PhoD-like phosphatase, N-terminal domain SusE PF14292.4 001306540.1_07629001_1 - 0.00047 20.4 2.9 5.6 7.3 0.1 4.9 5 0 0 5 5 5 2 SusE outer membrane protein V-set PF07686.15 001306540.1_07629001_1 - 0.00076 19.5 0.1 0.26 11.3 0.0 4.6 4 1 0 4 4 3 1 Immunoglobulin V-set domain Y_phosphatase3 PF13350.4 001306540.1_07629001_1 - 0.00087 19.2 0.1 0.59 9.9 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family DUF2369 PF10179.7 001306540.1_07629001_1 - 0.0011 19.3 0.0 11 6.5 0.0 4.9 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.3 001306540.1_07629001_1 - 0.0055 16.4 4.9 6 6.7 0.0 6.2 7 0 0 7 7 6 1 Fibronectin-III type domain V_ATPase_I PF01496.17 064035.6_07626001_1 - 2.9e-292 971.4 16.0 2.6e-228 759.8 0.7 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family QCR10 PF09796.7 064035.6_07626001_1 - 0.36 10.8 4.0 0.41 10.6 1.6 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RhoGAP PF00620.25 001027220.3_07622001_1 - 9.6e-41 139.0 0.1 1.3e-40 138.5 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain SIS PF01380.20 064078.5_07625001_1 - 3.1e-53 179.0 0.3 1.7e-32 111.8 0.0 2.8 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.4 064078.5_07625001_1 - 9.2e-21 74.3 0.0 2.1e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.4 064078.5_07625001_1 - 6.6e-15 55.0 0.0 1.4e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.4 064078.5_07625001_1 - 2.7e-05 23.1 0.1 5.4e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.4 064078.5_07625001_1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.9 1 1 0 1 1 1 0 SIS domain GATase_2 PF00310.19 064078.5_07625001_1 - 0.018 13.6 0.0 0.042 12.4 0.0 1.5 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Mtc PF03820.15 001267380.1_07621001_1 - 6.2e-55 186.3 0.1 6.8e-55 186.2 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Sdh5 PF03937.14 064206.4_07621001_1 - 9.3e-24 83.0 0.1 2.1e-23 81.9 0.1 1.6 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase 7TM_GPCR_Srz PF10325.7 064263.2_07622001_1 - 3.5e-43 147.7 36.9 4.4e-43 147.4 36.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srz DUF4736 PF15883.3 064263.2_07622001_1 - 0.95 9.0 8.9 2.3 7.8 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4736) DUF1412 PF07203.9 001027254.3_07621001_1 - 8.4e-33 112.2 0.3 9.7e-33 112.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1412) VWA PF00092.26 064343.1_07623001_1 - 3.5e-27 95.7 0.3 4.5e-27 95.3 0.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.4 064343.1_07623001_1 - 4.7e-09 36.8 0.1 7.9e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Rad17 PF03215.13 064392.5_07624001_1 - 6.8e-36 124.1 0.0 1.4e-33 116.5 0.0 2.8 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_29 PF13555.4 064392.5_07624001_1 - 0.002 17.7 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.27 064392.5_07624001_1 - 0.0043 17.3 0.0 0.0078 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 064392.5_07624001_1 - 0.01 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.4 064392.5_07624001_1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.20 064392.5_07624001_1 - 0.014 14.3 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_PrkA PF08298.9 064392.5_07624001_1 - 0.035 12.9 0.0 0.069 11.9 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain T2SSE PF00437.18 064392.5_07624001_1 - 0.036 13.0 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.25 064392.5_07624001_1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.4 064392.5_07624001_1 - 0.06 13.4 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.4 064392.5_07624001_1 - 0.072 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.15 064392.5_07624001_1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.20 064392.5_07624001_1 - 0.15 12.4 0.0 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase E2F_TDP PF02319.18 001129187.2_07622001_1 - 1e-21 76.6 0.6 2e-21 75.6 0.6 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.17 001129187.2_07622001_1 - 4.5e-07 29.5 0.1 8.7e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB E2F_CC-MB PF16421.3 001129187.2_07622001_1 - 4e-05 23.8 0.3 8.1e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain DUF4423 PF14394.4 001129187.2_07622001_1 - 0.0029 17.2 0.3 0.0051 16.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) B-block_TFIIIC PF04182.10 001129187.2_07622001_1 - 0.0035 17.3 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_11 PF08279.10 001129187.2_07622001_1 - 0.0048 16.7 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.5 001129187.2_07622001_1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.4 001129187.2_07622001_1 - 0.01 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.14 001129187.2_07622001_1 - 0.015 14.6 0.1 0.056 12.9 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_IclR PF09339.8 001129187.2_07622001_1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.4 001129187.2_07622001_1 - 0.023 14.1 0.1 0.023 14.1 0.1 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TnsD PF15978.3 001129187.2_07622001_1 - 0.03 13.2 0.2 0.049 12.5 0.2 1.3 1 0 0 1 1 1 0 Tn7-like transposition protein D eIF-4B PF06273.9 001129187.2_07622001_1 - 0.032 13.2 0.2 0.048 12.6 0.2 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B HTH_17 PF12728.5 001129187.2_07622001_1 - 0.033 14.3 0.1 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.18 001129187.2_07622001_1 - 0.04 14.1 0.1 0.083 13.1 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator UPF0122 PF04297.12 001129187.2_07622001_1 - 0.043 13.9 0.4 0.12 12.5 0.4 1.8 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_36 PF13730.4 001129187.2_07622001_1 - 0.064 13.1 0.1 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain RPA_C PF08784.9 001129187.2_07622001_1 - 0.073 13.6 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Replication protein A C terminal HTH_23 PF13384.4 001129187.2_07622001_1 - 0.093 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain EF-hand_1 PF00036.30 182166.5_07622001_1 - 1e-13 49.7 5.5 8.6e-07 28.0 1.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.4 182166.5_07622001_1 - 2.4e-10 39.4 5.8 1e-05 24.9 0.4 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.4 182166.5_07622001_1 - 8.8e-10 38.8 8.4 1e-09 38.6 2.6 3.1 1 1 2 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.4 182166.5_07622001_1 - 1.2e-07 31.2 2.2 0.004 16.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 182166.5_07622001_1 - 6.4e-06 25.3 4.8 0.0074 15.6 0.4 2.7 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.7 182166.5_07622001_1 - 2.6e-05 24.4 4.4 2.7e-05 24.3 0.3 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.11 182166.5_07622001_1 - 0.0079 16.0 1.5 0.092 12.5 0.7 2.2 1 1 1 2 2 2 1 Caleosin related protein MADF_DNA_bdg PF10545.7 064627.4_07623001_1 - 2.2e-19 69.4 1.0 2.2e-19 69.4 1.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.4 064627.4_07623001_1 - 0.0086 16.0 1.6 0.014 15.3 0.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.4 064627.4_07623001_1 - 0.043 14.1 0.3 0.043 14.1 0.3 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lin-8 PF03353.13 064627.4_07623001_1 - 0.62 9.4 7.7 0.96 8.8 7.7 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2360 PF10152.7 064627.4_07623001_1 - 3.2 8.0 13.6 0.28 11.4 7.4 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Roughex PF06020.9 064627.4_07623001_1 - 8.9 5.2 11.9 0.26 10.2 5.7 1.7 2 0 0 2 2 2 0 Drosophila roughex protein Ig_3 PF13927.4 064645.4_07629001_1 - 3.4e-143 466.4 28.2 9.7e-13 48.4 0.5 16.5 16 0 0 16 16 16 16 Immunoglobulin domain I-set PF07679.14 064645.4_07629001_1 - 1.1e-116 381.0 0.0 9.1e-11 41.6 0.0 17.4 16 1 0 16 16 16 15 Immunoglobulin I-set domain Ig_2 PF13895.4 064645.4_07629001_1 - 4.9e-114 372.7 11.1 2e-08 34.3 0.0 16.5 16 0 0 16 16 16 16 Immunoglobulin domain ig PF00047.23 064645.4_07629001_1 - 1.8e-84 277.9 0.2 1.3e-07 31.5 0.0 17.5 16 2 0 16 16 16 13 Immunoglobulin domain Laminin_B PF00052.16 064645.4_07629001_1 - 3e-68 227.7 0.1 9.8e-36 122.5 0.0 2.4 2 0 0 2 2 2 2 Laminin B (Domain IV) Laminin_EGF PF00053.22 064645.4_07629001_1 - 6.8e-34 115.6 145.4 2.9e-09 36.8 18.1 9.6 9 1 0 9 9 7 7 Laminin EGF domain Ldl_recept_a PF00057.16 064645.4_07629001_1 - 5.5e-32 109.6 75.6 2.7e-13 49.8 14.0 5.2 4 0 0 4 4 3 3 Low-density lipoprotein receptor domain class A V-set PF07686.15 064645.4_07629001_1 - 4e-31 107.3 23.5 0.0072 16.3 0.0 21.0 17 8 7 24 24 24 6 Immunoglobulin V-set domain Izumo-Ig PF16706.3 064645.4_07629001_1 - 1.8e-12 47.0 2.6 0.2 11.6 0.0 11.2 12 0 0 12 12 12 1 Izumo-like Immunoglobulin domain C1-set PF07654.13 064645.4_07629001_1 - 0.00059 20.1 2.8 0.33 11.3 0.0 6.6 8 1 0 8 8 6 1 Immunoglobulin C1-set domain DUF3301 PF11743.6 064645.4_07629001_1 - 0.023 14.3 0.2 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) C2-set_2 PF08205.10 064645.4_07629001_1 - 0.031 14.2 21.1 0.54 10.2 0.1 9.5 12 0 0 12 12 12 0 CD80-like C2-set immunoglobulin domain MerB PF03243.13 064645.4_07629001_2 - 0.052 13.5 3.5 0.57 10.1 0.8 2.9 2 0 0 2 2 2 0 Alkylmercury lyase GST_C_3 PF14497.4 171054.4_07622001_1 - 1.1e-12 47.9 0.5 3.3e-12 46.3 0.1 2.0 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 171054.4_07622001_1 - 1.3e-09 38.2 0.0 2.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 171054.4_07622001_1 - 3.8e-06 26.9 0.1 4.3e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 171054.4_07622001_1 - 3.9e-05 23.8 0.0 7.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 171054.4_07622001_1 - 0.023 14.9 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 171054.4_07622001_1 - 0.035 13.9 0.0 0.099 12.5 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain wnt PF00110.17 132572.1_07624120_1 - 1e-87 294.4 4.1 1.3e-87 294.1 4.1 1.1 1 0 0 1 1 1 1 wnt family wnt PF00110.17 132572.1_07624120_3 - 4.5e-11 42.7 17.2 4.5e-11 42.7 17.2 2.0 2 0 0 2 2 2 1 wnt family Hyccin PF09790.7 132576.1_07625120_1 - 1e-79 267.8 0.3 1.3e-79 267.4 0.3 1.1 1 0 0 1 1 1 1 Hyccin FBA_2 PF07735.15 133623.1_07624120_1 - 3.3e-11 43.0 2.6 3.3e-11 43.0 2.6 2.1 3 0 0 3 3 3 1 F-box associated IHHNV_capsid PF16530.3 133623.1_07624120_1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid VOMI PF03762.15 133628.1_07623120_1 - 1.6e-39 135.6 1.4 2.8e-39 134.8 1.4 1.4 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) MpPF26 PF07666.9 133628.1_07623120_2 - 0.012 15.5 0.3 0.027 14.4 0.3 1.5 1 0 0 1 1 1 0 M penetrans paralogue family 26 Rax2 PF12768.5 133628.1_07623120_2 - 0.039 13.4 0.6 0.055 12.9 0.6 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.4 133628.1_07623120_2 - 0.049 13.4 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family PIG-X PF08320.10 134551.1_07621120_1 - 0.061 13.1 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 PIG-X / PBN1 PT PF04886.10 134551.1_07621120_2 - 0.00091 18.6 2.1 0.0015 17.9 2.1 1.3 1 0 0 1 1 1 1 PT repeat 4HBT PF03061.20 134552.1_07624120_1 - 1.7e-07 31.3 0.1 0.029 14.6 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_2 PF13279.4 134552.1_07624120_1 - 0.025 14.9 0.6 3.2 8.1 0.0 3.1 2 1 1 3 3 3 0 Thioesterase-like superfamily SPK PF04435.16 131411.1_07623120_1 - 4e-24 84.9 0.9 4e-24 84.9 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF545) PHD PF00628.27 131411.1_07623120_1 - 7.1e-05 22.5 11.6 0.00015 21.4 11.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.4 131411.1_07623120_1 - 0.016 14.6 7.2 0.032 13.6 7.2 1.6 1 0 0 1 1 1 0 PHD-finger Guanylate_cyc PF00211.18 134556.1_07629120_1 - 3.8e-64 215.6 0.1 7e-64 214.7 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.26 134556.1_07629120_1 - 5e-38 131.0 4.1 5e-38 131.0 4.1 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region Pkinase_Tyr PF07714.15 134556.1_07629120_1 - 1.4e-35 122.7 0.0 3.9e-35 121.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 134556.1_07629120_1 - 2.7e-28 98.9 0.0 6.3e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.12 134556.1_07629120_1 - 0.0059 15.9 2.7 0.0059 15.9 2.7 1.9 2 0 0 2 2 2 1 Heme NO binding associated LOH1CR12 PF10158.7 132581.1_07622120_1 - 9.1e-60 200.3 0.0 1.3e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Tumour suppressor protein RE_Eco29kI PF09517.8 132581.1_07622120_1 - 0.026 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Eco29kI restriction endonuclease Apc13p PF05839.9 132581.1_07622120_1 - 0.17 11.9 0.7 0.45 10.6 0.2 1.9 2 0 0 2 2 2 0 Apc13p protein MAGE_N PF12440.6 132581.1_07622120_1 - 9.3 6.9 9.2 0.12 12.9 0.9 2.1 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal Solute_trans_a PF03619.14 136363.1_07624120_3 - 3.5e-15 56.1 15.3 5.2e-15 55.6 15.3 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2070 PF09843.7 136363.1_07624120_3 - 2.6 6.1 11.1 3.7 5.6 11.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PAP2 PF01569.19 132583.1_07623120_1 - 1.4e-22 79.9 2.2 2.7e-22 78.9 2.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.4 132583.1_07623120_1 - 0.00023 21.5 3.5 0.00023 21.5 3.5 2.1 2 0 0 2 2 2 1 PAP2 superfamily C-terminal Abhydrolase_9_N PF15420.4 132583.1_07623120_1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2976 PF11190.6 132583.1_07623120_1 - 0.035 13.8 1.1 0.47 10.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) PAP2 PF01569.19 132584.1_07623120_1 - 3.5e-09 36.4 0.1 7.7e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 PAP2 superfamily Abhydrolase_9_N PF15420.4 132584.1_07623120_1 - 0.027 14.3 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus PAP2 PF01569.19 132584.1_07623120_3 - 5.8e-09 35.7 0.7 5.8e-09 35.7 0.7 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.4 132584.1_07623120_3 - 0.035 14.5 0.4 0.035 14.5 0.4 2.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Spec3 PF15795.3 132584.1_07623120_3 - 0.67 10.4 4.6 0.29 11.6 0.5 2.3 2 2 0 2 2 2 0 Ectodermal ciliogenesis protein Collagen PF01391.16 145831.1_07624120_3 - 2.9e-16 58.8 109.5 0.00012 21.6 10.4 5.6 4 1 0 4 4 4 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.15 145831.1_07624120_3 - 1.8e-08 34.2 0.3 3.2e-08 33.4 0.3 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Sec62 PF03839.14 051341.1_07621120_2 - 0.27 10.6 0.5 0.29 10.5 0.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Pox_A_type_inc PF04508.10 051453.2_07628120_1 - 0.16 11.8 1.1 0.33 10.7 1.1 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Autophagy_act_C PF03987.13 051453.2_07628120_2 - 0.0035 17.8 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain zf-CCHC_2 PF13696.4 051453.2_07628120_2 - 0.016 14.9 1.3 0.039 13.6 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Sec62 PF03839.14 023948.1_07623120_1 - 4e-68 229.0 5.4 4e-68 229.0 5.4 2.2 1 1 1 2 2 2 1 Translocation protein Sec62 TIMELESS_C PF05029.11 023948.1_07623120_1 - 4.9e-08 32.5 4.3 7.1e-08 31.9 4.3 1.1 1 0 0 1 1 1 1 Timeless protein C terminal region DUF1510 PF07423.9 023948.1_07623120_1 - 4.1e-06 26.3 25.4 3.8e-05 23.1 6.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1510) LacY_symp PF01306.17 023948.1_07623120_1 - 0.0027 16.4 2.8 0.0036 16.0 2.8 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter DUF4834 PF16118.3 023948.1_07623120_1 - 0.0028 18.5 12.6 0.0066 17.3 0.4 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) VIT1 PF01988.17 023948.1_07623120_1 - 0.0071 16.1 5.2 0.012 15.3 0.0 2.3 2 0 0 2 2 2 1 VIT family SpoIIIAH PF12685.5 023948.1_07623120_1 - 0.0094 15.7 3.4 0.0094 15.7 3.4 2.4 3 0 0 3 3 3 2 SpoIIIAH-like protein SID-1_RNA_chan PF13965.4 023948.1_07623120_1 - 0.01 14.2 2.3 0.23 9.8 0.0 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Connexin PF00029.17 023948.1_07623120_1 - 0.012 15.3 1.8 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Connexin DUF1614 PF07758.9 023948.1_07623120_1 - 0.016 15.0 0.6 0.024 14.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) DUF913 PF06025.10 023948.1_07623120_1 - 0.033 13.0 14.5 0.075 11.9 1.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.12 023948.1_07623120_1 - 0.083 13.2 20.9 0.48 10.7 7.1 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 EOS1 PF12326.6 023948.1_07623120_1 - 0.26 11.1 1.7 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 N-glycosylation protein DDHD PF02862.15 023948.1_07623120_1 - 0.52 10.3 13.1 2.7 7.9 1.4 2.2 2 0 0 2 2 2 0 DDHD domain PEX11 PF05648.12 023948.1_07623120_1 - 0.62 9.4 0.0 0.62 9.4 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Gti1_Pac2 PF09729.7 023948.1_07623120_1 - 0.79 9.6 21.1 0.42 10.5 3.5 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DUF3341 PF11821.6 023948.1_07623120_1 - 1 8.8 3.3 1.8 8.1 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) CPSF100_C PF13299.4 023948.1_07623120_1 - 1.6 8.8 18.5 1.9 8.5 5.8 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.13 023948.1_07623120_1 - 1.7 7.4 6.1 3.9 6.2 0.2 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) Vfa1 PF08432.8 023948.1_07623120_1 - 1.7 8.8 42.0 0.61 10.3 15.7 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PA26 PF04636.11 023948.1_07623120_1 - 3.2 6.4 14.1 2 7.1 3.6 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) RXT2_N PF08595.9 023948.1_07623120_1 - 5.5 6.9 27.4 3.3 7.6 12.0 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal SAPS PF04499.13 023948.1_07623120_1 - 7 5.2 21.3 1.1 7.8 7.7 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Pkinase_Tyr PF07714.15 145829.1_07624120_3 - 3.2e-73 246.1 0.0 5.6e-73 245.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.23 145829.1_07624120_3 - 2.9e-48 164.4 0.0 4.6e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.22 145829.1_07624120_3 - 1.8e-08 34.2 0.0 4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Kdo PF06293.12 145829.1_07624120_3 - 0.049 12.8 0.2 0.12 11.6 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD1 PF04904.11 138506.1_07624120_1 - 7.1e-40 134.7 0.1 1.3e-39 134.0 0.1 1.4 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) NCD2 PF04905.11 138506.1_07624120_3 - 9.4e-60 201.0 0.0 1.7e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) RRM_1 PF00076.20 138514.1_07625120_2 - 1.2e-16 60.1 0.1 2.2e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 138514.1_07625120_2 - 0.023 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.4 138514.1_07625120_2 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 138514.1_07625120_3 - 0.018 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.7 138514.1_07625120_3 - 5.1 5.6 20.3 7 5.1 20.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PIG-P PF08510.10 132587.1_07626120_1 - 9.5e-17 60.9 2.1 1.7e-16 60.1 2.1 1.4 1 0 0 1 1 1 1 PIG-P MMR_HSR1 PF01926.21 132587.1_07626120_3 - 3.6e-07 30.1 0.0 1.5e-06 28.1 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.21 132587.1_07626120_3 - 0.0017 18.3 0.0 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.25 132587.1_07626120_3 - 0.0026 17.2 0.0 0.069 12.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.16 132587.1_07626120_3 - 0.0082 15.5 0.1 0.18 11.2 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Ras PF00071.20 132587.1_07626120_3 - 0.05 13.1 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.4 132587.1_07626120_3 - 0.092 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.14 132587.1_07626120_3 - 0.18 11.6 0.0 0.47 10.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Hormone_recep PF00104.28 181901.1_07624001_1 - 4.5e-22 78.5 0.4 6.8e-22 77.9 0.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 181901.1_07624001_1 - 1.2e-16 60.8 14.1 2.6e-16 59.7 14.1 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PEPCK PF00821.16 181904.3_07624001_1 - 9e-244 810.0 0.0 1e-243 809.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Complex1_LYR PF05347.13 064752.4_07622001_1 - 0.08 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) PHM7_cyt PF14703.4 064752.4_07622001_1 - 0.099 12.8 1.1 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF16 PF01519.14 064752.4_07622001_1 - 7 7.1 7.6 14 6.1 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function DUF16 Lipase_3 PF01764.23 171860.4_07625001_1 - 1.9e-18 66.6 0.0 3.4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.5 171860.4_07625001_1 - 0.071 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FTH PF01827.25 064959.1_07622001_1 - 2.3e-14 53.3 0.3 3.9e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 FTH domain F-box PF00646.31 064959.1_07622001_1 - 3.3e-05 23.5 0.1 9.2e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain Sec5 PF15469.4 064959.1_07622001_1 - 0.023 14.4 0.2 0.034 13.8 0.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 7tm_1 PF00001.19 065051.5_07623001_1 - 8.1e-70 235.0 0.0 1.4e-69 234.2 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EST1_DNA_bind PF10373.7 001047420.3_07627001_1 - 1.3e-51 175.6 0.9 2.1e-51 174.9 0.9 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.7 001047420.3_07627001_1 - 7.5e-15 55.6 0.1 7.5e-15 55.6 0.1 3.3 3 1 0 3 3 3 1 Telomerase activating protein Est1 PIN_4 PF13638.4 001047420.3_07627001_1 - 2.1e-07 31.2 0.9 0.00013 22.2 0.0 3.1 2 1 1 3 3 3 2 PIN domain DUF935 PF06074.10 001047420.3_07627001_1 - 0.0018 17.0 0.7 0.0031 16.2 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF935) Pannexin_like PF12534.6 001047420.3_07627001_1 - 0.024 13.6 0.9 0.056 12.4 0.9 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 EURL PF06937.9 001047420.3_07627001_1 - 0.23 10.7 4.0 3.4 6.9 2.4 2.3 2 0 0 2 2 2 0 EURL protein Dmrt1 PF12374.6 001047420.3_07627001_1 - 3.2 8.1 5.9 10 6.5 5.9 1.8 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Spb1_C PF07780.10 065254.5_07626001_1 - 9.3e-61 205.0 38.0 9.3e-61 205.0 38.0 3.7 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.17 065254.5_07626001_1 - 9.6e-58 195.1 0.1 1.8e-57 194.2 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.6 065254.5_07626001_1 - 4.4e-36 124.0 14.1 4.4e-36 124.0 14.1 5.1 4 1 2 6 6 6 1 Domain of unknown function (DUF3381) HECT PF00632.23 001330981.1_07628001_1 - 8.3e-78 261.8 0.7 1.9e-77 260.7 0.7 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.24 001330981.1_07628001_1 - 2.1e-12 46.6 2.1 3.8e-08 33.0 2.3 2.5 2 0 0 2 2 2 2 WW domain FBA_2 PF07735.15 001330981.1_07628001_1 - 1.6e-08 34.4 1.7 1.6e-08 34.4 1.7 3.1 3 0 0 3 3 3 1 F-box associated HECW_N PF16562.3 001330981.1_07628001_1 - 0.0054 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 DUF1106 PF06523.9 001330981.1_07628001_1 - 0.04 13.8 0.3 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1106) Shal-type PF11601.6 065706.4_07622001_1 - 4.1e-05 22.9 0.3 7.1e-05 22.1 0.3 1.3 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal tRNA-synt_1b PF00579.23 001026030.3_07623001_1 - 1.2e-69 234.8 0.0 1.5e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NIDO PF06119.12 065782.3_07627001_1 - 2.7e-30 105.1 0.6 1.3e-15 58.0 0.7 2.8 2 0 0 2 2 2 2 Nidogen-like EGF_3 PF12947.5 065782.3_07627001_1 - 2.6e-09 37.0 8.6 2.6e-09 37.0 8.6 3.8 3 1 0 3 3 3 2 EGF domain EGF_CA PF07645.13 065782.3_07627001_1 - 4.2e-08 33.1 10.9 4.2e-08 33.1 10.9 4.2 3 1 0 3 3 3 1 Calcium-binding EGF domain EGF PF00008.25 065782.3_07627001_1 - 3.6e-05 23.8 7.7 3.6e-05 23.8 7.7 4.1 3 1 1 4 4 4 1 EGF-like domain cEGF PF12662.5 065782.3_07627001_1 - 5.6e-05 22.9 4.1 5.6e-05 22.9 4.1 3.3 3 0 0 3 3 3 2 Complement Clr-like EGF-like hEGF PF12661.5 065782.3_07627001_1 - 0.0023 18.4 3.0 0.0023 18.4 3.0 4.6 4 1 2 6 6 6 1 Human growth factor-like EGF AJAP1_PANP_C PF15298.4 065782.3_07627001_1 - 0.0047 17.0 7.5 0.0047 17.0 7.5 2.1 2 0 0 2 2 2 1 AJAP1/PANP C-terminus DUF1679 PF07914.9 065784.4_07623001_1 - 1.3e-35 123.0 0.2 1.6e-35 122.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.21 065784.4_07623001_1 - 6.5e-14 52.3 0.0 9.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.18 065784.4_07623001_1 - 1.2e-13 51.0 0.2 4.1e-13 49.2 0.2 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.18 065784.4_07623001_1 - 4.8e-08 32.7 0.5 8e-08 32.0 0.5 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.12 065784.4_07623001_1 - 0.099 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ldl_recept_a PF00057.16 065836.7_07624001_1 - 1.5e-56 188.2 143.2 8.7e-10 38.5 5.3 10.2 9 1 1 10 10 10 8 Low-density lipoprotein receptor domain class A Flp1_like PF16982.3 065836.7_07624001_1 - 0.2 10.9 0.1 0.34 10.2 0.1 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Aldedh PF00171.20 065862.3_07624001_1 - 1.8e-133 445.3 0.2 2.2e-133 445.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Alpha-mann_mid PF09261.9 065862.3_07624001_2 - 0.11 12.7 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Alpha mannosidase middle domain Srg PF02118.19 001306705.1_07622001_1 - 3.2e-79 266.3 45.1 3.7e-79 266.1 45.1 1.0 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Sru PF10322.7 001306705.1_07622001_1 - 3.3e-06 26.5 40.6 5e-06 25.9 40.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru WD40 PF00400.30 065981.4_07624001_1 - 0.001 19.7 0.0 0.51 11.2 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Adap_comp_sub PF00928.19 066062.4_07624001_1 - 8.3e-31 107.2 1.4 1.2e-30 106.7 1.4 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.18 066062.4_07624001_1 - 6.6e-06 26.0 0.5 1.1e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.7 066062.4_07624001_1 - 0.0036 16.6 0.1 0.0056 16.0 0.1 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain UbiA PF01040.16 181955.4_07623001_1 - 1e-49 169.0 13.4 1.3e-49 168.6 13.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family SYF2 PF08231.10 066165.6_07622001_1 - 4.7e-46 157.0 6.2 4.7e-46 157.0 6.2 2.0 2 0 0 2 2 2 1 SYF2 splicing factor Transferase PF02458.13 066165.6_07622001_1 - 0.067 11.7 0.9 0.084 11.4 0.9 1.2 1 0 0 1 1 1 0 Transferase family SPARC_Ca_bdg PF10591.7 066165.6_07622001_1 - 5.2 7.3 9.5 1.4 9.1 6.0 1.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF972 PF06156.11 066165.6_07622001_2 - 1.5 9.3 5.2 0.98 9.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) OmdA PF13376.4 066165.6_07622001_2 - 2 8.3 6.2 1 9.3 0.5 2.9 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Ribul_P_3_epim PF00834.17 066219.5_07622001_1 - 1.9e-66 223.1 0.1 2.2e-66 222.9 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.17 066219.5_07622001_1 - 0.00076 19.2 0.0 0.0094 15.6 0.1 2.2 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.19 066219.5_07622001_1 - 0.0071 15.7 0.8 0.092 12.1 0.3 2.3 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.12 066219.5_07622001_1 - 0.011 14.9 0.6 0.016 14.4 0.6 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PRAI PF00697.20 066219.5_07622001_1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Alpha_L_fucos PF01120.15 066219.5_07622001_1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.4 1 1 0 1 1 1 0 Alpha-L-fucosidase zf-C2H2_4 PF13894.4 001027859.2_07622001_1 - 3.4e-10 39.7 15.5 0.0013 19.3 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.24 001027859.2_07622001_1 - 6.2e-08 32.5 15.8 0.0072 16.6 0.4 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.5 001027859.2_07622001_1 - 1.5e-06 28.3 14.9 0.00053 20.1 0.2 3.9 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.4 001027859.2_07622001_1 - 2e-06 27.8 8.2 8.5e-05 22.7 0.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.6 001027859.2_07622001_1 - 2.5e-06 27.5 15.3 0.00051 20.1 0.7 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001027859.2_07622001_1 - 0.00045 19.8 9.2 0.28 10.8 0.4 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type DUF4143 PF13635.4 001027859.2_07622001_1 - 0.0026 17.8 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4143) zf-C2H2_8 PF15909.3 001027859.2_07622001_1 - 0.0057 16.8 8.8 0.0088 16.2 0.6 3.2 2 2 1 3 3 3 1 C2H2-type zinc ribbon DUF2256 PF10013.7 001027859.2_07622001_1 - 0.014 15.4 2.5 0.86 9.6 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.10 001027859.2_07622001_1 - 0.031 14.3 4.3 0.62 10.1 0.1 2.8 3 0 0 3 3 3 0 DBF zinc finger FOXP-CC PF16159.3 001027859.2_07622001_1 - 0.046 14.2 2.2 7.3 7.2 0.1 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain Sgf11 PF08209.9 001027859.2_07622001_1 - 0.37 10.2 4.1 2.2 7.8 0.1 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_15 PF17032.3 001027859.2_07622001_1 - 0.46 11.1 9.1 0.64 10.7 1.0 2.7 1 1 1 2 2 2 0 zinc-ribbon family XPA_N PF01286.16 001027859.2_07622001_1 - 2.1 8.3 7.3 14 5.7 0.5 3.1 3 0 0 3 3 3 0 XPA protein N-terminal zf-BED PF02892.13 001027859.2_07622001_1 - 3.4 7.7 9.6 24 5.0 0.3 3.4 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.5 001027859.2_07622001_1 - 9.8 6.4 18.4 70 3.7 0.8 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) TIP41 PF04176.11 066312.5_07622001_1 - 1.1e-56 190.8 0.1 1.7e-56 190.3 0.1 1.2 1 0 0 1 1 1 1 TIP41-like family Proteasome PF00227.24 066405.4_07622001_1 - 2e-35 121.9 0.0 3.2e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit UBX PF00789.18 066455.4_07623001_1 - 4e-22 78.1 0.1 9.2e-22 76.9 0.1 1.7 1 0 0 1 1 1 1 UBX domain Med26_M PF15694.3 066455.4_07623001_1 - 0.01 15.8 11.3 0.01 15.8 11.3 1.8 2 0 0 2 2 2 0 Mediator complex subunit 26 middle domain DUF4776 PF16003.3 066455.4_07623001_1 - 0.63 8.8 13.1 0.92 8.3 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Hamartin PF04388.10 066455.4_07623001_1 - 1.1 7.6 10.3 1.7 7.1 10.3 1.2 1 0 0 1 1 1 0 Hamartin protein Hid1 PF12722.5 066455.4_07623001_1 - 7.7 4.3 8.6 10 3.9 8.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rpn3_C PF08375.9 066468.4_07624001_1 - 8.1e-25 86.9 2.8 2e-24 85.7 2.8 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.25 066468.4_07624001_1 - 3e-22 79.0 0.2 8.8e-22 77.5 0.2 1.8 1 0 0 1 1 1 1 PCI domain YfhD PF14151.4 066468.4_07624001_1 - 0.19 11.7 2.2 0.48 10.5 2.2 1.6 1 0 0 1 1 1 0 YfhD-like protein TPR_2 PF07719.15 066468.4_07624001_1 - 7.7 6.8 9.8 2.4 8.4 2.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ_C PF01556.16 066501.3_07623001_1 - 1.4e-27 96.5 0.0 2.4e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 066501.3_07623001_1 - 1.8e-24 85.5 6.3 4e-24 84.4 6.3 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.17 066501.3_07623001_1 - 2.5e-11 43.7 16.8 6.1e-11 42.4 16.8 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.3 066501.3_07623001_1 - 0.0021 17.8 9.7 0.22 11.4 1.8 2.7 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.17 066501.3_07623001_1 - 0.79 9.6 8.9 2.2 8.2 0.3 2.8 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.4 066501.3_07623001_1 - 4.8 7.6 12.2 0.46 10.8 5.9 2.5 2 0 0 2 2 2 0 Cytochrome c3 Rhodanese PF00581.18 066571.4_07622001_1 - 1.9e-11 44.3 0.0 4.5e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.23 066614.2_07622001_1 - 1.9e-12 47.0 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 066614.2_07622001_1 - 0.00099 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 066614.2_07622001_1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 066614.2_07622001_1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Leader_CPA1 PF08252.9 066614.2_07622001_2 - 0.11 11.8 0.5 0.22 10.8 0.5 1.5 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide IF-2B PF01008.15 066705.4_07622001_1 - 8.9e-84 280.9 0.2 1e-83 280.7 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Dynactin_p22 PF07426.9 066705.4_07622001_1 - 0.12 12.1 0.1 0.32 10.7 0.1 1.7 1 1 0 1 1 1 0 Dynactin subunit p22 Glyco_transf_7C PF02709.12 066763.6_07622001_1 - 1.7e-26 91.6 0.1 3e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.4 066763.6_07622001_1 - 7.5e-21 74.0 0.1 1.1e-20 73.5 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 CHGN PF05679.14 066763.6_07622001_1 - 0.0025 16.6 0.2 0.03 13.0 0.0 2.0 2 0 0 2 2 2 1 Chondroitin N-acetylgalactosaminyltransferase GCN5L1 PF06320.11 066861.4_07621001_1 - 1.1e-42 144.6 8.5 1.2e-42 144.5 8.5 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Prominin PF05478.9 066861.4_07621001_1 - 0.033 12.0 3.8 0.037 11.9 3.8 1.2 1 0 0 1 1 1 0 Prominin DUF4619 PF15398.4 066861.4_07621001_1 - 0.19 11.1 4.1 0.24 10.8 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) DNA_pol_E_B PF04042.14 066867.4_07624001_1 - 4.6e-41 140.4 0.6 1.2e-40 139.1 0.6 1.7 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B OMPdecase PF00215.22 066890.4_07623001_1 - 6.9e-51 172.9 0.1 9.2e-51 172.5 0.1 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.25 066890.4_07623001_1 - 3.5e-06 26.5 0.0 6.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.4 066890.4_07623001_1 - 0.03 13.7 0.1 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosyl transferase ArfGap PF01412.16 001027667.2_07626001_1 - 1.3e-39 134.7 0.0 5.5e-39 132.7 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ras PF00071.20 001027667.2_07626001_1 - 8e-21 74.2 0.1 1.6e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.5 001027667.2_07626001_1 - 4.1e-09 36.8 0.0 8.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001027667.2_07626001_1 - 2.3e-08 34.3 0.1 8.9e-06 26.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH PF00169.27 001027667.2_07626001_1 - 5.5e-08 33.1 1.1 0.0088 16.4 0.1 2.9 2 0 0 2 2 2 2 PH domain Ank PF00023.28 001027667.2_07626001_1 - 2.1e-06 27.8 0.1 9.7e-06 25.7 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.4 001027667.2_07626001_1 - 2.9e-05 24.0 0.0 0.031 14.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.4 001027667.2_07626001_1 - 0.00017 21.7 0.1 0.00037 20.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Roc PF08477.11 001027667.2_07626001_1 - 0.00024 21.2 0.0 0.0012 19.0 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PH_11 PF15413.4 001027667.2_07626001_1 - 0.00099 19.4 0.6 0.21 11.9 0.2 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain Arf PF00025.19 001027667.2_07626001_1 - 0.0043 16.4 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001027667.2_07626001_1 - 0.035 13.4 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Chitin_synth_1 PF01644.15 001027667.2_07626001_1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Chitin synthase HECT PF00632.23 066991.4_07627001_1 - 5.2e-89 298.6 0.2 1.2e-88 297.5 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) N6-adenineMlase PF10237.7 001268162.1_07622001_1 - 4.4e-47 159.7 0.0 5.4e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase DUF43 PF01861.14 001268162.1_07622001_1 - 0.024 13.7 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 Pkinase PF00069.23 067046.3_07624001_1 - 1.2e-68 231.3 0.0 1.6e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 067046.3_07624001_1 - 3.3e-33 114.9 0.0 4.8e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.22 067046.3_07624001_1 - 6.9e-10 39.3 2.8 1.9e-09 37.9 2.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.4 067046.3_07624001_1 - 4.8e-06 25.9 0.0 1.4e-05 24.5 0.0 1.7 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.4 067046.3_07624001_1 - 0.00039 20.0 0.0 0.54 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.12 067046.3_07624001_1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.9 067046.3_07624001_1 - 0.029 13.3 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Metallophos PF00149.26 067202.5_07623001_1 - 4.3e-40 138.3 0.0 5.8e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.3 067202.5_07623001_1 - 0.015 15.6 0.2 0.034 14.4 0.2 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.13 067202.5_07623001_1 - 0.079 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain CBFD_NFYB_HMF PF00808.21 067349.1_07622001_1 - 1.2e-20 73.4 1.0 2.6e-20 72.3 1.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 067349.1_07622001_1 - 1.2e-05 25.6 0.2 1.2e-05 25.6 0.2 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.12 067349.1_07622001_1 - 0.0015 18.3 4.4 0.0019 17.9 4.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CENP-W PF15510.4 067349.1_07622001_1 - 0.0056 16.8 0.9 0.011 15.9 0.1 1.8 2 0 0 2 2 2 1 CENP-W protein AAA_32 PF13654.4 067349.1_07622001_1 - 0.0091 14.7 0.1 0.0091 14.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain CENP-T_C PF15511.4 067349.1_07622001_1 - 0.024 14.6 0.5 0.043 13.8 0.4 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold MutS_I PF01624.18 067349.1_07622001_1 - 0.048 13.8 0.9 0.22 11.7 0.3 2.2 1 1 0 2 2 2 0 MutS domain I Virul_Fac PF10139.7 067349.1_07622001_1 - 0.061 11.4 4.8 0.1 10.7 4.8 1.3 1 1 0 1 1 1 0 Putative bacterial virulence factor TPR_1 PF00515.26 067410.3_07623001_1 - 5.8e-14 51.1 0.3 5.1e-06 26.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.15 067410.3_07623001_1 - 3e-13 48.7 0.7 0.0015 18.4 0.0 4.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.4 067410.3_07623001_1 - 2.6e-08 34.3 0.0 2.6e-08 34.3 0.0 3.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.4 067410.3_07623001_1 - 3.6e-07 29.6 3.5 0.0053 16.3 0.0 4.2 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.4 067410.3_07623001_1 - 5.2e-07 29.8 1.8 0.037 14.7 0.0 3.7 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.4 067410.3_07623001_1 - 2.5e-06 27.8 0.8 5.2e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.4 067410.3_07623001_1 - 1.1e-05 25.1 0.1 0.081 13.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.4 067410.3_07623001_1 - 1.3e-05 25.1 0.1 0.0076 16.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.4 067410.3_07623001_1 - 0.00074 19.5 0.1 0.011 15.7 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.4 067410.3_07623001_1 - 0.0021 18.2 0.1 0.22 11.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Motile_Sperm PF00635.24 067436.1_07622001_1 - 3.8e-24 84.5 2.5 3.8e-24 84.5 2.5 2.5 2 1 0 2 2 2 1 MSP (Major sperm protein) domain MIP-T3 PF10243.7 067436.1_07622001_1 - 0.00086 18.0 53.4 0.0011 17.6 53.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Presenilin PF01080.15 067436.1_07622001_1 - 0.0036 16.0 20.1 0.0042 15.8 20.1 1.3 1 0 0 1 1 1 1 Presenilin Nop14 PF04147.10 067436.1_07622001_1 - 0.0089 14.2 43.9 0.012 13.8 43.9 1.1 1 0 0 1 1 1 1 Nop14-like family DUF966 PF06136.11 067436.1_07622001_1 - 0.22 11.1 25.1 0.27 10.8 25.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.5 067436.1_07622001_1 - 6.1 4.7 25.2 7.6 4.3 25.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDM1 PF15501.4 067436.1_07622001_1 - 6.8 5.6 39.4 15 4.5 39.4 1.5 1 0 0 1 1 1 0 Nuclear protein MDM1 LAP1C PF05609.10 067436.1_07622001_1 - 8 5.3 30.2 12 4.7 30.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Crust_neurohorm PF01147.15 132449.1_07621120_3 - 5.4e-08 32.4 3.9 8.6e-08 31.8 3.9 1.4 1 1 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family BatA PF07584.9 052351.1_07622120_3 - 0.14 12.4 0.4 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal NMT_C PF02799.13 132450.1_07623120_1 - 3.2e-73 245.6 1.8 4.4e-73 245.1 1.8 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.17 132450.1_07623120_1 - 6e-73 243.8 0.0 1.8e-72 242.3 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.5 132450.1_07623120_1 - 4.7e-06 26.6 0.0 0.0007 19.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.23 132450.1_07623120_1 - 0.0098 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_trans_2_3 PF13632.4 132454.1_07623120_1 - 5.9e-43 146.9 1.5 5.9e-43 146.9 1.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.4 132454.1_07623120_1 - 4.4e-09 36.5 0.0 7.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fringe PF02434.14 132454.1_07623120_1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Fringe-like PET122 PF05476.9 132454.1_07623120_1 - 0.022 13.9 0.3 0.042 13.0 0.3 1.4 1 0 0 1 1 1 0 PET122 Prefoldin_2 PF01920.18 052645.1_07621120_2 - 0.00057 19.7 1.4 0.001 18.9 1.4 1.3 1 0 0 1 1 1 1 Prefoldin subunit TMCO5 PF14992.4 052645.1_07621120_2 - 0.0035 16.8 0.5 0.0037 16.7 0.5 1.2 1 0 0 1 1 1 1 TMCO5 family SlyX PF04102.10 052645.1_07621120_2 - 0.0062 17.0 0.4 0.012 16.0 0.2 1.5 2 0 0 2 2 2 1 SlyX DUF4201 PF13870.4 052645.1_07621120_2 - 0.028 14.0 0.7 0.028 14.0 0.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF148 PF02520.15 052645.1_07621120_2 - 0.056 13.4 0.8 0.075 13.0 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF148 ComC PF03047.12 052719.1_07621120_2 - 0.071 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 COMC family Homeobox PF00046.27 147825.1_07624120_1 - 5.3e-14 51.6 1.5 5.3e-14 51.6 1.5 2.0 2 0 0 2 2 2 1 Homeobox domain SPK PF04435.16 052832.1_07621120_1 - 0.019 15.2 0.1 0.025 14.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF545) SPK PF04435.16 052832.1_07621120_2 - 6.6e-21 74.6 0.2 8.8e-21 74.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF545) Inhibitor_I9 PF05922.14 052832.1_07621120_2 - 0.077 13.5 0.1 0.11 13.0 0.1 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 DUF1192 PF06698.9 132456.1_07622120_1 - 0.0019 18.1 0.6 0.0038 17.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) CENP-Q PF13094.4 132456.1_07622120_1 - 0.012 15.7 2.0 0.019 15.0 2.0 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Coa1 PF08695.8 001356895.1_07621001_1 - 5.9e-07 29.1 0.0 6.6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF559 PF04480.10 001356895.1_07621001_2 - 0.055 13.2 0.1 0.086 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF559) RE_Eco29kI PF09517.8 001356895.1_07621001_2 - 0.095 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Eco29kI restriction endonuclease Filamin PF00630.17 001268292.1_07629001_1 - 3.9e-158 515.7 29.0 5.3e-16 59.2 0.0 19.2 19 1 0 19 19 19 17 Filamin/ABP280 repeat CH PF00307.29 001268292.1_07629001_1 - 2.7e-42 143.2 1.8 4.1e-22 78.3 2.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.11 001268292.1_07629001_1 - 3e-09 36.6 0.2 21 5.0 0.0 8.6 9 0 0 9 9 9 0 Y_Y_Y domain CAMSAP_CH PF11971.6 001268292.1_07629001_1 - 7.3e-05 22.4 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain DUF5060 PF16586.3 001268292.1_07629001_1 - 0.00013 22.1 0.0 44 4.4 0.0 6.9 7 0 0 7 7 7 0 Domain of unknown function (DUF5060) Big_1 PF02369.14 001268292.1_07629001_1 - 0.00049 19.9 0.1 3.1 7.7 0.0 5.6 6 0 0 6 6 6 1 Bacterial Ig-like domain (group 1) PPC PF04151.13 001268292.1_07629001_1 - 0.002 19.1 5.7 30 5.7 0.0 6.3 6 0 0 6 6 5 0 Bacterial pre-peptidase C-terminal domain DUF2012 PF09430.8 001268292.1_07629001_1 - 0.017 15.1 0.0 0.074 13.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DUF4369 PF14289.4 001268292.1_07629001_1 - 0.038 14.5 0.4 1.4 9.5 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4369) Big_3_5 PF16640.3 001268292.1_07629001_1 - 0.084 12.9 11.1 0.26 11.4 0.0 7.0 9 1 1 10 10 10 0 Bacterial Ig-like domain (group 3) CH_2 PF06294.9 001268292.1_07629001_1 - 0.086 12.8 1.1 16 5.6 0.8 2.5 2 0 0 2 2 2 0 CH-like domain in sperm protein HTH_3 PF01381.20 001268292.1_07629001_2 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix RNase_T PF00929.22 171245.4_07623001_1 - 1.8e-42 145.6 0.4 5.4e-42 144.0 0.0 2.0 3 0 0 3 3 3 1 Exonuclease SAP PF02037.25 171245.4_07623001_1 - 3.8e-06 26.4 0.1 9.9e-06 25.1 0.1 1.8 1 0 0 1 1 1 1 SAP domain zf-H2C2_2 PF13465.4 001307473.1_07621001_1 - 1e-22 79.3 22.5 8.8e-09 35.3 1.5 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.24 001307473.1_07621001_1 - 6.9e-17 60.7 22.3 1.8e-07 31.1 0.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001307473.1_07621001_1 - 6.2e-12 45.1 18.5 0.00034 21.1 2.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger Zf_RING PF16744.3 001307473.1_07621001_1 - 0.00056 19.8 2.9 0.13 12.2 0.1 2.4 1 1 1 2 2 2 2 KIAA1045 RING finger zf-C2H2_8 PF15909.3 001307473.1_07621001_1 - 0.00087 19.4 6.8 0.008 16.3 1.8 2.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.5 001307473.1_07621001_1 - 0.002 18.3 13.2 0.26 11.6 1.3 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001307473.1_07621001_1 - 0.0051 16.6 20.3 0.055 13.3 0.5 4.0 4 1 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.4 001307473.1_07621001_1 - 0.0057 16.3 1.3 0.0057 16.3 1.3 4.1 4 1 0 4 4 4 2 C2H2-type zinc-finger domain zf-BED PF02892.13 001307473.1_07621001_1 - 0.011 15.6 13.5 0.051 13.5 3.7 3.5 1 1 2 3 3 3 0 BED zinc finger zf-RING_11 PF17123.3 001307473.1_07621001_1 - 0.055 13.1 2.0 2.4 7.8 0.0 2.9 3 0 0 3 3 3 0 RING-like zinc finger HHH_4 PF14490.4 001307473.1_07621001_1 - 0.11 12.4 0.0 15 5.6 0.0 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix containing domain zf-C2H2_jaz PF12171.6 001307473.1_07621001_1 - 0.74 10.1 16.7 0.84 9.9 0.1 4.1 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding DENN PF02141.19 001307456.1_07629001_1 - 3.1e-58 196.7 0.9 4e-57 193.0 1.0 2.2 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.16 001307456.1_07629001_1 - 3e-16 59.9 0.4 1.3e-15 57.8 0.2 2.3 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.17 001307456.1_07629001_1 - 5.6e-12 45.3 7.2 1.3e-11 44.2 7.2 1.7 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.4 001307456.1_07629001_1 - 1.1e-06 28.7 0.3 2.3e-05 24.4 0.0 2.9 2 1 1 3 3 3 2 PPR repeat family PPR_3 PF13812.4 001307456.1_07629001_1 - 0.0056 16.6 0.1 0.12 12.3 0.1 2.4 1 1 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.18 001307456.1_07629001_1 - 0.022 14.9 0.6 0.062 13.4 0.1 2.1 2 0 0 2 2 2 0 PPR repeat PPR_long PF17177.2 001307456.1_07629001_1 - 0.084 12.1 0.0 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PROPR CPSF_A PF03178.13 001307656.1_07628001_1 - 4.2e-77 259.5 0.0 1.9e-76 257.3 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.7 001307656.1_07628001_1 - 4.6e-39 134.2 0.0 8e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Glyco_hydro_15 PF00723.19 001307665.1_07624001_1 - 2e-12 46.5 0.0 2.6e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF1840 PF08895.9 001307665.1_07624001_1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF2975 PF11188.6 068140.3_07625001_1 - 0.4 10.4 9.5 0.23 11.2 6.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Ion_trans PF00520.29 068140.3_07625001_1 - 0.64 9.1 30.1 0.012 14.7 22.2 2.3 2 1 0 2 2 2 0 Ion transport protein 7TM_GPCR_Str PF10326.7 068301.1_07622001_1 - 1.7e-21 76.7 31.1 2.1e-21 76.4 31.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.7 068301.1_07622001_1 - 1.4e-10 40.9 27.6 1.7e-10 40.6 27.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.7 068301.1_07622001_1 - 2.3e-05 23.4 12.8 2.3e-05 23.4 12.8 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srd PF10317.7 068301.1_07622001_1 - 0.0016 17.5 35.8 0.029 13.4 35.8 3.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd DUF1467 PF07330.10 068301.1_07622001_1 - 0.45 10.3 11.7 2.5 8.0 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) Hist_deacetyl PF00850.17 001129308.2_07626001_1 - 6.3e-165 547.9 1.5 5.7e-90 301.8 0.0 2.1 2 0 0 2 2 2 2 Histone deacetylase domain zf-UBP PF02148.17 001129308.2_07626001_1 - 1.3e-17 63.7 9.3 4e-17 62.2 9.3 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein ZU5 PF00791.18 068422.5_07626001_1 - 1.3e-22 79.8 0.0 3.1e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.4 068422.5_07626001_1 - 6.5e-17 61.8 0.3 1.1e-13 51.5 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 068422.5_07626001_1 - 8.1e-16 58.0 0.3 1.4e-14 54.0 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Death PF00531.20 068422.5_07626001_1 - 5.4e-13 48.8 0.0 9.6e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Death domain I-set PF07679.14 068422.5_07626001_1 - 6.2e-13 48.5 0.0 2.5e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain UPA PF17217.1 068422.5_07626001_1 - 2.4e-10 40.5 0.0 4.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 UPA domain ig PF00047.23 068422.5_07626001_1 - 4.8e-09 36.1 0.0 4e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 068422.5_07626001_1 - 6.5e-07 29.3 0.3 0.012 15.6 0.0 2.8 1 1 1 2 2 2 2 Immunoglobulin V-set domain TSP_1 PF00090.17 068422.5_07626001_1 - 4.2e-06 26.7 8.2 4.2e-06 26.7 8.2 4.1 4 0 0 4 4 3 2 Thrombospondin type 1 domain V-set_CD47 PF08204.9 068422.5_07626001_1 - 0.009 15.9 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain PMP22_Claudin PF00822.18 068422.5_07626001_1 - 0.04 13.7 0.1 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family C2-set_2 PF08205.10 068422.5_07626001_1 - 0.054 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain NTS_2 PF15448.4 068422.5_07626001_1 - 0.058 13.8 0.7 3.9 7.9 0.0 2.8 2 1 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein Receptor_2B4 PF11465.6 068422.5_07626001_1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 bZIP_Maf PF03131.15 001306754.1_07622001_1 - 2.2e-10 40.8 4.4 2.2e-10 40.8 4.4 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.19 001306754.1_07622001_1 - 0.0012 18.8 6.3 0.0038 17.2 6.3 1.8 1 0 0 1 1 1 1 bZIP transcription factor SWIRM-assoc_2 PF16496.3 001306754.1_07622001_1 - 0.13 11.0 2.8 0.16 10.7 2.8 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal bZIP_2 PF07716.13 001306754.1_07622001_1 - 0.17 11.8 6.8 0.24 11.4 5.6 1.9 1 1 0 1 1 1 0 Basic region leucine zipper DUF2959 PF11172.6 001306754.1_07622001_2 - 0.075 12.9 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) PseudoU_synth_1 PF01416.18 001306850.1_07622001_1 - 1.5e-09 38.1 0.0 2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase Cadherin_C_2 PF16492.3 001028407.3_07623001_1 - 0.00034 21.2 1.9 0.17 12.5 0.0 3.5 3 1 0 3 3 3 1 Cadherin cytoplasmic C-terminal Ctr PF04145.13 001028407.3_07623001_1 - 0.007 16.9 0.1 1.8 9.1 0.0 2.3 2 0 0 2 2 2 1 Ctr copper transporter family DUF2448 PF10476.7 001028407.3_07623001_1 - 0.0098 15.7 0.3 1.3 8.7 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2448) EphA2_TM PF14575.4 001028407.3_07623001_1 - 0.047 14.4 0.1 7.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.3 001028407.3_07623001_1 - 0.062 14.1 9.1 13 6.6 7.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) Ly49 PF08391.8 001028407.3_07623001_1 - 0.079 13.2 1.9 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region PsbH PF00737.18 001028407.3_07623001_1 - 0.13 11.9 0.3 0.27 10.9 0.3 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein CD20 PF04103.13 001028407.3_07623001_1 - 4.1 7.3 8.5 13 5.7 3.1 2.4 2 0 0 2 2 2 0 CD20-like family VRR_NUC PF08774.9 068596.4_07626001_1 - 8.1e-31 106.2 0.0 2.2e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain ResIII PF04851.13 068617.7_07627001_1 - 4e-19 69.1 1.1 1.2e-18 67.5 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RIG-I_C-RD PF11648.6 068617.7_07627001_1 - 1.1e-18 67.5 0.7 3.1e-18 66.0 0.7 1.8 1 0 0 1 1 1 1 C-terminal domain of RIG-I DEAD PF00270.27 068617.7_07627001_1 - 4.5e-17 62.2 0.0 1.5e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 068617.7_07627001_1 - 6.3e-16 58.6 0.2 2.9e-15 56.4 0.2 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.4 068617.7_07627001_1 - 0.0012 19.0 0.2 0.011 15.9 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.4 068617.7_07627001_1 - 0.0059 16.8 0.0 0.018 15.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain Sec34 PF04136.13 068617.7_07627001_1 - 0.0097 15.7 0.3 0.031 14.0 0.3 1.9 1 0 0 1 1 1 1 Sec34-like family T2SSE PF00437.18 068617.7_07627001_1 - 0.014 14.4 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.10 068617.7_07627001_1 - 0.038 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.7 068617.7_07627001_1 - 0.043 12.9 0.0 0.089 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Yippee-Mis18 PF03226.12 068617.7_07627001_1 - 0.044 13.9 2.2 0.14 12.2 2.2 1.9 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA PF00004.27 068617.7_07627001_1 - 0.062 13.6 0.0 0.33 11.2 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.4 068617.7_07627001_1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.19 068617.7_07627001_1 - 1 8.7 5.4 3.4 7.0 0.0 3.3 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Acetyltransf_10 PF13673.5 001083194.2_07622001_1 - 0.00048 19.9 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.23 001083194.2_07622001_1 - 0.00057 20.0 0.0 0.00094 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.5 001083194.2_07622001_1 - 0.0055 17.0 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Trehalase PF01204.16 001306845.1_07624001_1 - 6e-173 576.2 0.0 8.1e-173 575.8 0.0 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.12 001306845.1_07624001_1 - 0.00063 18.7 0.0 0.00086 18.2 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_63 PF03200.14 001306845.1_07624001_1 - 0.013 14.2 0.6 0.044 12.4 0.1 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 C-terminal domain Bac_rhamnosid PF05592.9 001306845.1_07624001_1 - 0.043 12.2 0.2 3.4 5.9 0.0 2.6 3 0 0 3 3 3 0 Bacterial alpha-L-rhamnosidase Glyco_hydro_18 PF00704.26 068681.4_07627001_1 - 4.3e-59 200.7 0.1 3.4e-35 122.1 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolases family 18 Bestrophin PF01062.19 001028173.4_07623001_1 - 1.5e-88 296.8 6.5 1.9e-88 296.5 6.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel EF-G-binding_N PF07299.9 001307220.2_07629001_1 - 1.1 9.7 4.2 7.5 7.0 0.6 4.7 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal FARP PF01581.14 068854.1_07621001_1 - 1.8e-20 69.3 2.4 1.8 9.3 0.0 9.4 9 0 0 9 9 9 9 FMRFamide related peptide family DUF3248 PF11609.6 068854.1_07621001_1 - 0.12 12.1 0.4 52 3.7 0.0 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3248) 7tm_1 PF00001.19 001027917.4_07623001_1 - 9.5e-46 156.1 24.7 1.2e-45 155.7 24.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001027917.4_07623001_1 - 8e-09 35.1 20.6 1.6e-08 34.1 20.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001027917.4_07623001_1 - 0.063 12.4 26.8 0.018 14.2 22.0 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001027917.4_07623001_1 - 0.1 12.2 12.9 0.22 11.1 12.9 1.5 1 1 0 1 1 1 0 Olfactory receptor Peptidase_A22B PF04258.11 001307235.1_07621001_1 - 0.0038 16.7 0.5 0.0041 16.5 0.5 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Oxidored_q2 PF00420.22 001307235.1_07621001_1 - 1.5 8.3 5.7 2.4 7.7 2.2 2.6 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L UCR_UQCRX_QCR9 PF05365.10 001307235.1_07621001_1 - 2.9 7.8 10.5 3.3 7.6 0.2 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-C4 PF00105.16 001307205.1_07625001_1 - 4e-20 71.9 12.0 9.9e-20 70.6 12.0 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001307205.1_07625001_1 - 6.6e-10 38.8 1.1 6.6e-10 38.8 1.1 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor TFIIA PF03153.11 001307205.1_07625001_1 - 0.12 12.2 9.7 0.21 11.4 9.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YscJ_FliF_C PF08345.9 001307205.1_07625001_1 - 0.4 10.8 5.9 0.058 13.6 1.6 1.8 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal Spt20 PF12090.6 001307205.1_07625001_1 - 1.2 8.6 11.5 2.8 7.4 11.5 1.6 1 0 0 1 1 1 0 Spt20 family Tmemb_40 PF10160.7 001268428.1_07623001_1 - 1.1e-81 273.8 13.4 1.4e-81 273.6 13.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein 7tm_1 PF00001.19 182289.3_07623001_1 - 7.4e-45 153.1 17.9 9.2e-45 152.8 17.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 182289.3_07623001_1 - 6.9e-07 28.8 20.1 2.5e-06 26.9 20.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 182289.3_07623001_1 - 0.31 10.6 11.7 0.1 12.2 8.5 1.8 1 1 0 1 1 1 0 Olfactory receptor DUF2116 PF09889.7 182289.3_07623001_1 - 5 7.0 5.9 19 5.2 0.1 3.9 4 0 0 4 4 4 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Motile_Sperm PF00635.24 069361.5_07621001_1 - 1.2e-24 86.1 0.0 1.4e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Sortase PF04203.11 069361.5_07621001_1 - 0.05 13.3 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Sortase family Nucleoside_tran PF01733.16 001268522.1_07623001_1 - 5.3e-66 223.0 21.0 5.3e-66 223.0 21.0 3.2 1 1 1 3 3 3 1 Nucleoside transporter MFS_1 PF07690.14 001268522.1_07623001_1 - 0.0056 15.5 47.5 0.011 14.6 3.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily FMO-like PF00743.17 069567.4_07624001_1 - 1.1e-168 561.9 0.1 1.2e-168 561.7 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 069567.4_07624001_1 - 6.9e-23 81.2 0.1 6.4e-19 68.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.12 069567.4_07624001_1 - 5.3e-13 48.7 0.0 1.2e-11 44.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 069567.4_07624001_1 - 7.8e-12 44.8 0.0 4.3e-11 42.4 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.25 069567.4_07624001_1 - 1.2e-06 28.9 1.0 0.0011 19.4 0.2 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 069567.4_07624001_1 - 0.00029 20.9 0.0 0.00091 19.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 069567.4_07624001_1 - 0.00062 19.4 0.6 1.1 8.6 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.4 069567.4_07624001_1 - 0.003 17.5 0.1 0.057 13.3 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.17 069567.4_07624001_1 - 0.016 14.4 0.0 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.4 069567.4_07624001_1 - 0.054 13.8 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.15 069567.4_07624001_1 - 0.084 12.0 0.1 9.6 5.2 0.1 2.2 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.14 069567.4_07624001_1 - 0.14 11.7 0.0 0.88 9.1 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.17 069567.4_07624001_1 - 0.21 10.7 1.2 4.1 6.4 0.1 2.7 2 0 0 2 2 2 0 FAD binding domain 6PGD PF00393.17 069597.5_07623001_1 - 2.1e-126 421.0 0.0 2.9e-126 420.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.13 069597.5_07623001_1 - 1.4e-49 168.2 0.0 2.1e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.10 069597.5_07623001_1 - 0.00046 19.7 0.2 0.15 11.5 0.1 2.5 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_11 PF14833.4 069597.5_07623001_1 - 0.0065 16.6 0.2 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DNA_pol3_beta PF00712.17 069597.5_07623001_1 - 0.035 14.1 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain Histone_H2A_C PF16211.3 069740.1_07621001_1 - 1.5e-20 72.4 1.0 3.1e-20 71.5 1.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.22 069740.1_07621001_1 - 2.4e-15 57.0 0.0 2.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 069740.1_07621001_1 - 2.1e-06 27.8 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.3 001276859.1_07621001_1 - 1.7e-20 72.3 1.0 3.5e-20 71.3 1.0 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.22 001276859.1_07621001_1 - 2.8e-15 56.7 0.0 3.6e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001276859.1_07621001_1 - 2.5e-06 27.5 0.0 3.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Piwi PF02171.15 069816.1_07627001_1 - 4e-109 364.3 2.0 5.6e-109 363.9 2.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.3 069816.1_07627001_1 - 1e-13 52.0 0.0 2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.20 069816.1_07627001_1 - 7.1e-13 48.4 0.2 1.5e-12 47.3 0.0 1.7 2 0 0 2 2 2 1 PAZ domain ArgoL1 PF08699.8 069816.1_07627001_1 - 1.4e-10 40.5 0.0 3.6e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.3 069816.1_07627001_1 - 4.4e-10 39.6 0.0 9.9e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.3 069816.1_07627001_1 - 9.9e-07 28.8 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute Collagen PF01391.16 069971.6_07622001_1 - 1.5e-24 85.3 113.5 8e-10 38.2 39.6 4.3 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.15 069971.6_07622001_1 - 1.4e-19 69.7 1.0 1.8e-19 69.4 1.0 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain 7TM_GPCR_Sru PF10322.7 069992.2_07622001_1 - 4.1e-110 367.7 33.8 4.7e-110 367.5 33.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru Srg PF02118.19 069992.2_07622001_1 - 1.5e-11 44.3 27.6 3e-11 43.4 27.6 1.4 1 1 0 1 1 1 1 Srg family chemoreceptor Pex24p PF06398.9 069992.2_07622001_1 - 0.041 12.7 0.0 0.041 12.7 0.0 2.3 1 1 2 3 3 3 0 Integral peroxisomal membrane peroxin CUB_2 PF02408.18 070071.1_07623001_1 - 6.5e-35 119.4 3.7 6.5e-35 119.4 3.7 1.9 2 0 0 2 2 2 1 CUB-like domain Ammonium_transp PF00909.19 070095.3_07624001_1 - 3.9e-127 424.1 18.8 4.6e-127 423.9 18.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UPF0029 PF01205.17 070095.3_07624001_1 - 0.047 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 tRNA-synt_1c PF00749.19 001268916.1_07623001_1 - 1.6e-58 198.0 0.0 2.2e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.16 001268916.1_07623001_1 - 1.7e-45 154.9 0.0 3.1e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF1096 PF06493.9 070471.1_07623001_1 - 2.9e-23 81.9 26.4 2.9e-23 81.9 26.4 9.1 4 3 3 7 7 7 1 Protein of unknown function (DUF1096) C_tripleX PF02363.17 070471.1_07623001_1 - 0.011 15.8 11.6 0.011 15.8 11.6 14.7 14 3 2 16 16 16 0 Cysteine rich repeat CLIP PF12032.6 070471.1_07623001_2 - 0.99 9.6 3.8 7.2 6.8 1.3 2.7 1 1 1 2 2 2 0 Regulatory CLIP domain of proteinases Guanylate_cyc PF00211.18 001307188.1_07626001_1 - 7.1e-47 159.3 0.1 2.5e-46 157.5 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.15 001307188.1_07626001_1 - 5.7e-16 58.4 0.4 3.8e-13 49.2 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ANF_receptor PF01094.26 001307188.1_07626001_1 - 5.2e-13 48.7 0.0 1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.23 001307188.1_07626001_1 - 5.6e-11 42.2 1.5 2.7e-10 39.9 1.3 2.0 1 1 1 2 2 2 1 Protein kinase domain HNOBA PF07701.12 001307188.1_07626001_1 - 0.00087 18.7 0.3 0.0018 17.6 0.3 1.5 1 0 0 1 1 1 1 Heme NO binding associated MIF4G PF02854.17 001307188.1_07626001_1 - 0.013 15.1 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 MIF4G domain 7TM_GPCR_Srz PF10325.7 001028415.1_07622001_1 - 1.1e-75 254.3 43.3 1.4e-75 254.0 43.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srz Rhomboid PF01694.20 001313038.1_07626001_1 - 4.8e-37 127.1 3.9 4.8e-37 127.1 3.9 1.8 2 0 0 2 2 2 1 Rhomboid family Homeobox PF00046.27 070680.2_07622001_1 - 3.7e-13 48.9 3.9 7.9e-10 38.3 0.0 2.9 3 0 0 3 3 3 2 Homeobox domain Homeobox_KN PF05920.9 070680.2_07622001_1 - 2e-10 40.3 0.1 1e-06 28.4 0.1 2.6 2 0 0 2 2 2 2 Homeobox KN domain Homez PF11569.6 070680.2_07622001_1 - 1e-05 24.7 0.2 0.082 12.3 0.0 2.8 3 0 0 3 3 3 2 Homeodomain leucine-zipper encoding, Homez KilA-N PF04383.11 070680.2_07622001_1 - 0.02 14.6 3.3 0.54 10.0 0.3 2.8 3 0 0 3 3 3 0 KilA-N domain MerR_1 PF13411.4 070680.2_07622001_1 - 0.039 13.9 0.2 11 6.0 0.0 2.9 3 0 0 3 3 3 0 MerR HTH family regulatory protein CAP PF00188.24 101891.1_07621120_2 - 0.00088 20.0 0.1 0.0012 19.6 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RCR PF12273.6 136368.1_07622120_2 - 0.001 19.5 0.1 0.0019 18.7 0.1 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Baculo_11_kDa PF06143.9 136368.1_07622120_2 - 0.0029 17.0 1.3 0.005 16.2 1.3 1.3 1 0 0 1 1 1 1 Baculovirus 11 kDa family EphA2_TM PF14575.4 136368.1_07622120_2 - 0.019 15.6 1.1 0.033 14.9 1.1 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF948 PF06103.9 136368.1_07622120_2 - 0.047 13.8 0.2 0.083 13.0 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) WBP-1 PF11669.6 136368.1_07622120_2 - 0.055 14.0 0.5 0.14 12.7 0.5 1.7 1 1 0 1 1 1 0 WW domain-binding protein 1 CYYR1 PF10873.6 136368.1_07622120_2 - 0.077 13.3 0.4 0.13 12.6 0.4 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF1772 PF08592.9 136368.1_07622120_2 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF912 PF06024.10 136368.1_07622120_2 - 0.13 12.4 0.1 0.26 11.4 0.1 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4389 PF14333.4 136368.1_07622120_2 - 0.14 12.0 0.3 0.21 11.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DUF2749 PF10907.6 136368.1_07622120_2 - 0.41 10.7 3.0 0.2 11.8 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) TMEM52 PF14979.4 136368.1_07622120_2 - 3.9 7.2 8.7 37 4.1 4.8 2.8 1 1 1 2 2 2 0 Transmembrane 52 Shisa PF13908.4 136368.1_07622120_2 - 5.9 7.0 5.8 1.4 9.0 0.6 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator CT47 PF15623.4 138528.1_07624120_1 - 7.5 6.3 8.0 11 5.8 8.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF1505 PF07403.9 101897.1_07621120_3 - 3.7e-11 43.0 0.3 4.9e-11 42.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1505) ANF_receptor PF01094.26 132462.1_07626120_1 - 2.4e-59 201.1 0.0 3.1e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.20 132462.1_07626120_1 - 6.3e-55 186.4 26.3 1e-54 185.7 26.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.12 132462.1_07626120_1 - 4.4e-11 42.5 13.6 9.7e-11 41.4 13.6 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 132462.1_07626120_1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein S-AdoMet_synt_N PF00438.18 131525.1_07624120_1 - 5.9e-19 68.5 0.2 8.9e-19 67.9 0.2 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_C PF02773.14 131525.1_07624120_2 - 1.4e-68 229.0 0.0 3.4e-68 227.8 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.14 131525.1_07624120_2 - 4.6e-45 152.6 0.0 7.8e-45 151.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.18 131525.1_07624120_2 - 4.6e-17 62.4 0.1 9.5e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.15 131525.1_07624120_2 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase S-AdoMet_synt_N PF00438.18 131528.1_07623120_1 - 1.4e-36 125.0 0.3 2.4e-36 124.2 0.3 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_C PF02773.14 131528.1_07623120_3 - 3.4e-68 227.8 0.0 8.8e-68 226.5 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.14 131528.1_07623120_3 - 3.7e-45 152.9 0.0 5.5e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain Amidinotransf PF02274.15 131528.1_07623120_3 - 0.085 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Amidinotransferase DUF272 PF03312.13 131541.1_07623120_1 - 6.6e-31 107.0 0.7 2.1e-30 105.4 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF272) DNA_ligase_OB_2 PF14743.4 131541.1_07623120_1 - 0.0059 16.5 6.7 2.4 8.1 0.1 5.2 2 1 3 5 5 5 1 DNA ligase OB-like domain Ribonuc_red_sm PF00268.19 131542.1_07623120_1 - 2e-103 345.6 2.0 2.8e-103 345.1 2.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain AA_permease_2 PF13520.4 131543.1_07624120_1 - 6.4e-05 21.8 2.8 8.6e-05 21.4 2.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.4 131543.1_07624120_3 - 4.1e-36 124.6 37.7 5.8e-36 124.1 37.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.19 131543.1_07624120_3 - 1.5e-14 53.3 30.2 1.5e-14 53.3 30.2 1.5 2 0 0 2 2 2 1 Amino acid permease WSN PF02206.16 131548.1_07627120_3 - 1.4e-15 56.8 1.5 6e-15 54.8 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function Adeno_E3_CR2 PF02439.13 131548.1_07627120_3 - 0.0083 15.7 0.5 0.018 14.6 0.5 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.18 131548.1_07627120_3 - 0.14 12.0 0.2 0.37 10.6 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain DUF2207 PF09972.7 131548.1_07627120_3 - 0.29 9.7 0.0 0.29 9.7 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) COX16 PF14138.4 131548.1_07627120_3 - 0.7 10.3 4.2 0.64 10.5 1.7 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF1179 PF06678.9 131548.1_07627120_3 - 0.86 9.5 4.7 0.48 10.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1179) Exo70 PF03081.13 056048.1_07621120_2 - 0.018 14.1 0.2 0.018 14.1 0.2 1.0 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Gemini_AL3 PF01407.15 056048.1_07621120_2 - 0.048 13.4 0.1 0.05 13.3 0.1 1.1 1 0 0 1 1 1 0 Geminivirus AL3 protein BAR PF03114.16 131563.1_07622120_1 - 0.014 14.9 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 BAR domain TPR_MLP1_2 PF07926.10 131563.1_07622120_2 - 0.0057 16.6 1.8 0.0088 16.0 1.8 1.3 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein ApoLp-III PF07464.9 131564.1_07623120_3 - 0.00027 20.9 0.5 0.00057 19.9 0.3 1.6 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF3510 PF12022.6 131564.1_07623120_3 - 0.046 14.0 0.3 0.16 12.2 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) PHO4 PF01384.18 131566.1_07624120_1 - 3.9e-56 190.4 10.8 3.9e-56 190.4 10.8 1.6 1 1 0 1 1 1 1 Phosphate transporter family DUF4040 PF13244.4 131566.1_07624120_1 - 0.0084 16.1 1.9 0.0084 16.1 1.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4040) PHO4 PF01384.18 131566.1_07624120_3 - 1.6e-60 204.8 0.1 1.6e-60 204.8 0.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family TMEM51 PF15345.4 056181.1_07621120_3 - 0.042 13.5 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 7tm_1 PF00001.19 131572.1_07623120_1 - 8.8e-07 28.3 3.0 1.4e-06 27.6 3.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.19 131572.1_07623120_2 - 2.2e-33 115.5 18.5 3.3e-33 114.9 18.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.20 131573.1_07622120_1 - 1.5e-18 66.2 0.0 2.2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 131573.1_07622120_1 - 4.5e-05 23.4 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.4 131573.1_07622120_1 - 0.00059 19.3 0.0 0.00088 18.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.7 131573.1_07622120_2 - 0.085 11.4 14.4 0.1 11.2 14.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.10 131573.1_07622120_2 - 8.9 6.4 51.2 14 5.7 51.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Neurensin PF14927.4 131575.1_07621120_3 - 0.055 13.1 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Neurensin CYSTM PF12734.5 131575.1_07621120_3 - 0.45 10.8 21.1 32 4.8 21.1 2.5 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Peptidase_M20 PF01546.26 131576.1_07624120_1 - 2.7e-21 76.1 0.0 3.4e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.12 131576.1_07624120_1 - 1.1e-18 67.0 0.0 2.5e-18 65.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.15 131576.1_07624120_1 - 0.0092 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.26 131576.1_07624120_2 - 1.1e-07 31.6 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Phage_30_8 PF06019.9 056279.1_07621120_1 - 0.066 13.0 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 Phage GP30.8 protein ABC_export PF16962.3 056449.1_07621120_2 - 0.071 11.4 2.8 0.073 11.4 2.8 1.1 1 0 0 1 1 1 0 Putative ABC exporter Pkinase_Tyr PF07714.15 131592.1_07623120_1 - 2.3e-84 282.6 0.3 2.9e-84 282.3 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 131592.1_07623120_1 - 1.8e-45 155.2 0.4 2.8e-45 154.6 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.22 131592.1_07623120_1 - 1.8e-10 40.6 0.0 4.6e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.4 131592.1_07623120_1 - 0.0006 19.1 0.0 0.0026 17.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like zf-C4 PF00105.16 138498.1_07624120_2 - 2.1e-25 88.8 12.4 4.4e-25 87.8 12.4 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Ion_trans_2 PF07885.14 101961.1_07625120_3 - 3.1e-26 91.0 12.0 7.9e-15 54.5 0.6 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.29 101961.1_07625120_3 - 3.7e-07 29.5 7.0 0.0036 16.4 0.1 2.3 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.18 101961.1_07625120_3 - 0.15 10.8 1.2 0.89 8.3 0.0 2.3 2 0 0 2 2 2 0 Inward rectifier potassium channel DUF3188 PF11384.6 056664.1_07622120_2 - 0.017 14.7 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DUF2371 PF10177.7 056664.1_07622120_2 - 0.046 13.8 0.1 0.16 12.0 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF2207 PF09972.7 056664.1_07622120_2 - 0.1 11.2 0.0 0.28 9.8 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) UPF0197 PF05251.10 056664.1_07622120_2 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) FA_hydroxylase PF04116.11 056672.1_07621120_3 - 0.031 14.5 2.3 0.046 13.9 2.3 1.4 1 1 0 1 1 1 0 Fatty acid hydroxylase superfamily His_Phos_2 PF00328.20 131610.1_07624120_3 - 1.8e-07 30.7 0.0 3.8e-05 23.1 0.0 2.4 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.20 003454.1_07623120_1 - 0.0061 16.2 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.4 003454.1_07623120_3 - 5.7e-08 33.1 3.6 5.7e-08 33.1 3.6 2.4 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 UDPGT PF00201.16 131619.1_07623120_2 - 5.1e-37 127.7 0.0 6.2e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 131619.1_07623120_2 - 3.8e-05 23.6 0.0 5.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF1265 PF06887.12 131622.1_07623120_2 - 5.8e-19 67.7 2.2 5.8e-19 67.7 2.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1265) DUF1265 PF06887.12 131623.1_07623120_2 - 2.3e-19 68.9 2.2 4.9e-19 67.9 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1265) DUF1265 PF06887.12 131624.1_07622120_2 - 4.8e-19 67.9 2.2 4.8e-19 67.9 2.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1265) BTB PF00651.29 131639.1_07622120_2 - 2.1e-10 40.7 0.1 3.7e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_C2 PF00648.19 131640.1_07625120_1 - 9.5e-105 349.7 0.1 1.2e-104 349.4 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.20 131640.1_07625120_3 - 1.8e-26 93.0 0.1 4.9e-25 88.3 0.0 2.3 2 0 0 2 2 2 1 Calpain large subunit, domain III C2 PF00168.28 131640.1_07625120_3 - 0.00073 19.7 0.2 0.003 17.7 0.1 2.0 2 0 0 2 2 2 1 C2 domain Methyltransf_23 PF13489.4 131652.1_07621120_3 - 4.9e-08 32.9 0.0 5.8e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 131652.1_07621120_3 - 0.039 14.5 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1639 PF07797.12 131655.1_07621120_1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) zf-C4 PF00105.16 101983.1_07625120_1 - 3.1e-13 49.8 2.4 6.4e-13 48.8 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 101983.1_07625120_3 - 7.7e-20 71.2 0.0 1.6e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 101983.1_07625120_3 - 0.01 16.1 5.6 0.028 14.8 5.6 1.8 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) DUF4440 PF14534.4 131663.1_07621120_3 - 2e-10 40.8 0.0 2.4e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.5 131663.1_07621120_3 - 1.5e-05 25.4 0.0 1.8e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.4 131663.1_07621120_3 - 5.3e-05 23.3 0.1 6.5e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF3225 PF11533.6 131663.1_07621120_3 - 0.0098 15.5 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) SnoaL PF07366.10 131663.1_07621120_3 - 0.014 15.0 0.0 0.021 14.5 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_4 PF13577.4 131663.1_07621120_3 - 0.023 14.7 0.1 0.029 14.3 0.1 1.2 1 1 0 1 1 1 0 SnoaL-like domain 7TM_GPCR_Srz PF10325.7 131666.1_07622120_1 - 1.8e-08 33.9 1.9 1.8e-08 33.9 1.9 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srz 7TM_GPCR_Srz PF10325.7 131666.1_07622120_3 - 4.2e-59 199.9 39.4 5.8e-59 199.5 39.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srz DnaJ PF00226.29 003159.1_07623120_1 - 1.1e-09 38.1 0.2 1.6e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.11 003159.1_07623120_1 - 1.6e-06 27.6 2.8 2.8e-06 26.8 2.8 1.4 1 0 0 1 1 1 1 CSL zinc finger CAP_N PF01213.17 003159.1_07623120_2 - 0.0022 17.4 3.5 0.0032 16.9 3.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.9 003159.1_07623120_2 - 1.6 8.6 6.9 2.6 7.9 6.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Roc PF08477.11 003159.1_07623120_3 - 6.2e-14 52.1 0.0 4.5e-13 49.4 0.0 2.0 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 003159.1_07623120_3 - 1.6e-11 44.0 0.0 9.6e-11 41.4 0.0 2.0 1 1 0 1 1 1 1 Ras family Arf PF00025.19 003159.1_07623120_3 - 0.016 14.5 0.1 0.17 11.2 0.0 2.4 2 1 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.21 003159.1_07623120_3 - 0.061 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase NIP_1 PF08995.8 003159.1_07623120_3 - 0.14 12.4 1.0 0.25 11.6 0.1 1.9 2 0 0 2 2 2 0 Necrosis inducing protein-1 DUF258 PF03193.14 003159.1_07623120_3 - 0.14 11.9 0.0 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF1777 PF08648.10 132466.1_07625120_1 - 1.9 8.6 48.8 0.5 10.5 45.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.7 132466.1_07625120_1 - 2.4 6.7 20.4 4 5.9 20.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SF1-HH PF16275.3 132466.1_07625120_3 - 2.8e-21 75.8 0.5 5.9e-21 74.8 0.5 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.27 132466.1_07625120_3 - 3.2e-08 33.1 0.0 6.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.21 132466.1_07625120_3 - 3e-05 23.8 1.9 3e-05 23.8 1.9 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.4 132466.1_07625120_3 - 0.0002 21.1 5.9 0.056 13.3 0.5 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.4 132466.1_07625120_3 - 0.00028 20.5 1.3 0.00028 20.5 1.3 2.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.4 132466.1_07625120_3 - 0.021 14.4 1.1 0.021 14.4 1.1 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.4 132466.1_07625120_3 - 5.3 6.5 19.6 14 5.1 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Fructosamin_kin PF03881.12 132467.1_07621120_1 - 1.5e-10 40.6 0.1 2e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 Fructosamine kinase Glyco_hydro_30 PF02055.14 132469.1_07624120_1 - 2e-129 431.4 2.4 2.4e-129 431.2 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30 PF02055.14 132469.1_07624120_3 - 2.2e-31 109.0 0.3 2.9e-31 108.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.2 132469.1_07624120_3 - 1.7e-05 24.8 1.6 2.5e-05 24.3 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain PI-PLC-X PF00388.17 001313102.1_07628001_1 - 1.4e-57 193.2 0.0 4.2e-57 191.7 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.17 001313102.1_07628001_1 - 9.5e-41 138.6 0.1 9.5e-41 138.6 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF1154 PF06631.9 001313102.1_07628001_1 - 6.7e-17 61.1 8.7 6.7e-17 61.1 8.7 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1154) EF-hand_like PF09279.9 001313102.1_07628001_1 - 1.1e-09 38.5 0.1 1.1e-09 38.5 0.1 3.8 5 0 0 5 5 5 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.28 001313102.1_07628001_1 - 9.7e-07 28.9 0.0 2.8e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain PLC-beta_C PF08703.8 001313102.1_07628001_1 - 0.0028 17.5 26.1 0.0028 17.5 26.1 2.3 2 0 0 2 2 2 1 PLC-beta C terminal Pkinase PF00069.23 070759.4_07622001_1 - 1.2e-53 182.1 0.0 1.3e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 070759.4_07622001_1 - 4.4e-28 98.1 0.0 5.2e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1987 PF09345.8 070759.4_07622001_1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) 7TM_GPCR_Srh PF10318.7 070802.1_07623001_1 - 3.9e-31 108.1 23.5 4.5e-31 107.9 23.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srd PF10317.7 070802.1_07623001_1 - 1.4e-06 27.6 22.7 1.7e-06 27.3 22.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Hormone_recep PF00104.28 070813.1_07623001_1 - 5.7e-55 186.0 4.0 5.7e-55 186.0 4.0 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 070813.1_07623001_1 - 1.4e-16 60.6 15.8 2.7e-16 59.6 15.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) LHH PF14411.4 070813.1_07623001_1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH 7TM_GPCR_Srbc PF10316.7 070899.3_07622001_1 - 1.7e-88 296.5 32.9 2e-88 296.3 32.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srbc PF10316.7 070922.1_07622001_1 - 1.4e-91 306.7 33.6 1.6e-91 306.5 33.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.19 070922.1_07622001_1 - 0.45 9.6 15.4 0.29 10.2 13.5 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Glyco_hydro_18 PF00704.26 071019.3_07623001_1 - 0.00013 21.6 0.0 0.00038 20.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 7TM_GPCR_Str PF10326.7 071178.2_07622001_1 - 2e-44 152.1 20.5 2.5e-44 151.7 20.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.7 071178.2_07622001_1 - 1.4e-11 44.2 16.9 1.6e-11 44.0 16.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srd PF10317.7 071178.2_07622001_1 - 0.0059 15.7 18.4 0.0082 15.2 18.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Hormone_recep PF00104.28 071201.5_07623001_1 - 1.2e-51 175.1 1.0 2e-51 174.4 1.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 071201.5_07623001_1 - 4e-15 55.9 13.4 7.2e-15 55.1 13.4 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.14 071201.5_07623001_1 - 5.4 7.3 12.1 1.3 9.3 0.3 2.5 2 0 0 2 2 2 0 C1 domain Hormone_recep PF00104.28 001038398.2_07623001_1 - 7.3e-50 169.3 6.2 7.3e-50 169.3 6.2 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001038398.2_07623001_1 - 5.1e-17 62.0 9.7 9.6e-17 61.1 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.3 001038398.2_07623001_1 - 0.016 15.2 3.1 0.051 13.6 3.1 1.8 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_2 PF03107.14 001038398.2_07623001_1 - 3.2 8.0 11.2 0.58 10.4 0.5 2.7 1 1 1 2 2 2 0 C1 domain Recep_L_domain PF01030.22 001316835.1_07623001_1 - 1.2e-21 76.7 13.6 2.8e-16 59.5 6.3 2.7 2 1 0 2 2 2 2 Receptor L domain Recep_L_domain PF01030.22 071248.1_07623001_1 - 3.8e-23 81.6 19.9 3.7e-16 59.1 6.4 3.4 2 1 2 4 4 4 4 Receptor L domain 7TM_GPCR_Srd PF10317.7 071291.1_07622001_1 - 8.4e-79 264.7 33.2 9.6e-79 264.5 33.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srh PF10318.7 071291.1_07622001_1 - 4.5e-13 48.8 31.7 5.8e-13 48.4 31.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Str PF10326.7 071291.1_07622001_1 - 6.8e-10 38.6 30.4 2.2e-08 33.7 30.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.7 071291.1_07622001_1 - 0.001 18.3 21.7 0.0038 16.5 21.7 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srt PF10321.7 071434.3_07622001_1 - 5.5e-87 291.5 26.9 6.8e-87 291.2 26.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.7 071434.3_07622001_1 - 9.9e-08 31.5 21.2 9.9e-08 31.5 21.2 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx FixQ PF05545.9 071434.3_07622001_1 - 0.013 15.3 0.3 0.013 15.3 0.3 3.2 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Abi PF02517.14 071434.3_07622001_1 - 8 6.8 19.3 2.5 8.4 3.1 3.6 2 2 1 3 3 3 0 CAAX protease self-immunity 7TM_GPCR_Str PF10326.7 071448.1_07622001_1 - 1.6e-84 283.7 25.9 1.9e-84 283.5 25.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.7 071448.1_07622001_1 - 5.1e-27 94.9 23.2 5.7e-27 94.7 23.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.7 071448.1_07622001_1 - 1e-09 37.7 17.2 1e-09 37.7 17.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.7 071448.1_07622001_1 - 0.00015 20.9 15.5 0.00037 19.7 15.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Srd PF10317.7 071448.1_07622001_1 - 0.0018 17.4 28.8 0.0046 16.1 28.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srj PF10319.7 071562.1_07623001_1 - 5.4e-126 420.0 25.2 6.4e-126 419.7 25.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Str PF10326.7 071562.1_07623001_1 - 3e-68 230.3 27.3 3.4e-68 230.1 27.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srd PF10317.7 071562.1_07623001_1 - 7.1e-27 94.2 25.6 1e-26 93.7 25.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srh PF10318.7 071562.1_07623001_1 - 5e-13 48.6 28.5 1.6e-12 46.9 28.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.7 071562.1_07623001_1 - 1.4e-12 47.3 24.2 2.2e-12 46.6 24.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri DUF747 PF05346.9 071562.1_07623001_1 - 0.006 15.9 1.0 0.011 15.1 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic membrane protein family Caprin-1_C PF12287.6 071562.1_07623001_3 - 0.037 14.0 0.7 0.052 13.6 0.1 1.4 2 0 0 2 2 2 0 Cytoplasmic activation/proliferation-associated protein-1 C term zf-C4 PF00105.16 071669.5_07623001_1 - 3.4e-17 62.5 13.0 9.1e-17 61.1 13.0 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 071669.5_07623001_1 - 2.4e-12 46.8 0.0 4.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF2318 PF10080.7 071669.5_07623001_1 - 0.035 14.1 4.3 0.11 12.5 4.3 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) p450 PF00067.20 071698.1_07623001_1 - 9.2e-91 304.8 0.0 1.1e-90 304.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fip1 PF05182.11 071802.4_07624001_1 - 9.2e-25 85.7 1.0 1.7e-24 84.9 1.0 1.5 1 0 0 1 1 1 1 Fip1 motif DUF591 PF04569.12 071802.4_07624001_2 - 0.75 10.1 7.0 1.5 9.1 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function UDPGT PF00201.16 071908.5_07624001_1 - 3.2e-49 168.0 0.1 3.5e-49 167.8 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 071908.5_07624001_1 - 1.8e-13 50.6 0.0 4.2e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.4 071908.5_07624001_1 - 0.011 14.9 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 1 C_tripleX PF02363.17 071983.1_07623001_1 - 0.011 15.9 28.1 0.022 14.9 10.1 14.7 14 2 0 14 14 14 0 Cysteine rich repeat Neur_chan_LBD PF02931.21 072040.5_07623001_1 - 1.6e-45 155.1 0.0 2.3e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 072040.5_07623001_1 - 5.4e-32 111.6 0.3 4e-28 99.0 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region C_tripleX PF02363.17 001129376.2_07624001_1 - 1.6e-07 31.0 449.2 0.011 15.8 7.9 24.2 25 1 1 26 26 26 19 Cysteine rich repeat EF-hand_4 PF12763.5 001356659.1_07624001_1 - 1e-16 60.6 0.0 4.9e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.3 001356659.1_07624001_1 - 1.9e-15 56.3 3.1 4.3e-15 55.2 3.1 1.7 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.21 001356659.1_07624001_1 - 5.3e-14 52.5 0.0 7.1e-13 48.8 0.0 2.5 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.21 001356659.1_07624001_1 - 8.4e-09 35.4 0.0 1.8e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.30 001356659.1_07624001_1 - 0.00015 20.9 0.3 0.00073 18.8 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.4 001356659.1_07624001_1 - 0.01 15.5 1.5 4.7 6.9 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair Roc PF08477.11 001356659.1_07624001_1 - 0.011 15.8 0.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.10 001356659.1_07624001_1 - 0.013 14.8 0.0 0.074 12.3 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region EF-hand_6 PF13405.4 001356659.1_07624001_1 - 0.014 15.2 0.1 0.082 12.8 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain DUF258 PF03193.14 001356659.1_07624001_1 - 0.019 14.8 0.0 2.3 8.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.4 001356659.1_07624001_1 - 0.02 15.1 0.1 0.72 10.1 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain EF-hand_5 PF13202.4 001356659.1_07624001_1 - 0.025 14.0 0.3 0.082 12.3 0.3 1.9 1 0 0 1 1 1 0 EF hand AAA_28 PF13521.4 001356659.1_07624001_1 - 0.046 13.8 0.1 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.4 001356659.1_07624001_1 - 0.096 13.1 0.1 9.1 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.17 001356659.1_07624001_1 - 0.14 11.6 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.4 001356659.1_07624001_1 - 0.15 12.2 0.0 3.3 7.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain FTH PF01827.25 072214.1_07623001_1 - 7.2e-32 110.0 6.4 1.8e-31 108.7 6.4 1.7 1 0 0 1 1 1 1 FTH domain F-box PF00646.31 072214.1_07623001_1 - 8.8e-07 28.5 0.1 2.1e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain Hormone_recep PF00104.28 072397.5_07623001_1 - 5e-28 98.0 0.0 7.9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 072397.5_07623001_1 - 3.8e-12 46.3 14.5 7.6e-12 45.4 14.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF267 PF03268.12 072469.3_07621001_1 - 0.0026 16.6 1.1 0.0028 16.5 1.1 1.0 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF267 Hormone_recep PF00104.28 072469.3_07621001_1 - 0.0089 15.5 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Myosin_head PF00063.19 072693.3_07629001_1 - 3.3e-288 957.4 3.9 3.3e-288 957.4 3.9 3.7 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.17 072693.3_07629001_1 - 1.3e-151 506.6 268.0 1.7e-151 506.2 268.0 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.17 072693.3_07629001_1 - 8.2e-14 51.0 5.8 2.1e-13 49.7 5.8 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Syntaxin-6_N PF09177.9 072693.3_07629001_1 - 7.6e-06 26.3 6.9 7.6e-06 26.3 6.9 12.3 4 2 2 7 7 7 1 Syntaxin 6, N-terminal Filament PF00038.19 072693.3_07629001_1 - 1.7e-05 24.5 50.2 1.7e-05 24.5 50.2 7.8 1 1 3 5 5 5 2 Intermediate filament protein DUF745 PF05335.11 072693.3_07629001_1 - 0.00073 19.2 16.8 0.00073 19.2 16.8 10.9 5 2 8 13 13 13 4 Protein of unknown function (DUF745) Reo_sigmaC PF04582.10 072693.3_07629001_1 - 0.56 9.4 68.8 0.085 12.1 3.6 8.3 2 1 7 9 9 9 0 Reovirus sigma C capsid protein IQ PF00612.25 072693.3_07629001_1 - 2.3 8.1 9.0 0.12 12.1 0.3 3.0 3 0 0 3 3 3 0 IQ calmodulin-binding motif DUF4265 PF14085.4 072693.3_07629001_1 - 2.6 7.9 6.4 1.9 8.3 0.6 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4265) Img2 PF05046.12 072693.3_07629001_1 - 7.6 6.8 8.3 10 6.3 0.1 5.2 5 0 0 5 5 5 0 Mitochondrial large subunit ribosomal protein (Img2) SNAP PF14938.4 072698.3_07622001_1 - 1.2e-104 349.6 16.2 1.3e-104 349.4 16.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.4 072698.3_07622001_1 - 3.8e-06 26.9 6.7 0.00096 19.3 0.3 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.7 072698.3_07622001_1 - 0.0089 15.6 3.9 0.042 13.4 0.9 2.8 1 1 1 2 2 2 1 26S proteasome subunit RPN7 NSF PF02071.18 072698.3_07622001_1 - 0.011 16.2 27.0 1.1 10.1 0.4 8.1 10 0 0 10 10 10 0 Aromatic-di-Alanine (AdAR) repeat TPR_6 PF13174.4 072698.3_07622001_1 - 0.015 15.8 9.4 13 6.6 0.1 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_9 PF00759.17 072698.3_07622001_1 - 0.04 13.2 4.0 0.046 13.0 4.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 ANAPC3 PF12895.5 072698.3_07622001_1 - 0.051 13.6 1.7 0.051 13.6 1.7 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Spatacsin_C PF14649.4 072698.3_07622001_1 - 0.51 9.3 8.6 11 4.9 8.8 2.5 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_2 PF07719.15 072698.3_07622001_1 - 2.6 8.3 19.2 29 5.0 0.0 6.4 6 1 2 8 8 7 0 Tetratricopeptide repeat TIMP PF00965.15 072712.5_07621001_1 - 1.7e-13 50.7 0.0 2.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.19 072712.5_07621001_1 - 2.9e-05 23.7 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Metallophos PF00149.26 072715.5_07622001_1 - 2.8e-18 67.0 3.5 4.1e-18 66.5 3.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.5 072715.5_07622001_1 - 2.2e-06 27.9 1.7 1.4e-05 25.3 1.7 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Histone PF00125.22 072798.1_07621001_1 - 1.4e-54 183.9 2.8 1.6e-54 183.7 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 072798.1_07621001_1 - 0.00011 22.2 0.5 0.00017 21.5 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.4 072798.1_07621001_1 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.21 072798.1_07621001_1 - 0.0083 16.3 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.3 072798.1_07621001_1 - 0.02 15.4 1.9 0.028 14.9 1.9 1.3 1 0 0 1 1 1 0 PCNA-associated factor TFIID-31kDa PF02291.13 072798.1_07621001_1 - 0.027 14.4 0.1 0.047 13.6 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.22 072875.1_07621001_1 - 1.4e-54 183.9 2.8 1.6e-54 183.7 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 072875.1_07621001_1 - 0.00011 22.2 0.5 0.00017 21.5 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.4 072875.1_07621001_1 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.21 072875.1_07621001_1 - 0.0083 16.3 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.3 072875.1_07621001_1 - 0.02 15.4 1.9 0.028 14.9 1.9 1.3 1 0 0 1 1 1 0 PCNA-associated factor TFIID-31kDa PF02291.13 072875.1_07621001_1 - 0.027 14.4 0.1 0.047 13.6 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit 7TM_GPCR_Srx PF10328.7 072929.1_07623001_1 - 2.2e-16 59.9 33.3 2.8e-16 59.5 33.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.7 072929.1_07623001_1 - 0.00031 20.1 26.8 0.00093 18.5 26.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv HSP20 PF00011.19 072955.3_07621001_1 - 2.5e-23 82.0 0.4 3.1e-23 81.7 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family IMUP PF15761.3 073017.4_07621001_1 - 0.021 15.3 2.4 0.34 11.5 0.4 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein MAD PF05557.11 073061.4_07625001_1 - 1.9e-06 26.4 39.9 1.7e-05 23.3 21.3 3.4 2 1 0 2 2 2 2 Mitotic checkpoint protein Spc7 PF08317.9 073061.4_07625001_1 - 1.5 7.5 34.3 0.14 10.9 7.3 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein GAS PF13851.4 073061.4_07625001_1 - 2.4 7.4 40.9 1.1 8.4 10.2 4.4 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding SHE3 PF17078.3 073061.4_07625001_1 - 4.7 6.7 32.4 0.093 12.3 14.2 3.8 4 0 0 4 4 4 0 SWI5-dependent HO expression protein 3 DUF2316 PF10078.7 073061.4_07625001_1 - 7.8 6.7 10.8 0.11 12.7 0.9 3.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) RNase_T PF00929.22 001269256.1_07622001_1 - 1.1e-34 120.2 0.1 1.3e-34 120.0 0.1 1.0 1 0 0 1 1 1 1 Exonuclease Osmo_CC PF08946.8 001269256.1_07622001_1 - 0.01 15.9 0.1 0.87 9.7 0.0 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil UDPGT PF00201.16 073327.4_07624001_1 - 9.6e-59 199.3 0.2 1.2e-58 199.0 0.2 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 073327.4_07624001_1 - 1.4e-11 44.5 0.0 2.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.4 073327.4_07624001_1 - 0.068 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF2648 PF10855.6 001269335.1_07622001_1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) ECSCR PF15820.3 001269335.1_07622001_1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4245 PF14030.4 001269335.1_07622001_1 - 0.058 13.3 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Collagen PF01391.16 073461.6_07622001_1 - 4.4e-05 23.0 10.7 8.1e-05 22.2 10.7 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Furin-like_2 PF15913.3 073461.6_07622001_1 - 0.041 13.9 0.9 0.47 10.5 0.3 2.3 2 0 0 2 2 2 0 Furin-like repeat, cysteine-rich Globin PF00042.20 073546.4_07622001_1 - 0.0012 19.3 0.1 0.0022 18.4 0.1 1.4 1 0 0 1 1 1 1 Globin ADH_N PF08240.10 073590.5_07623001_1 - 6.1e-28 96.8 1.1 6.1e-28 96.8 1.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.24 073590.5_07623001_1 - 1.5e-27 96.0 0.2 2.2e-27 95.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.17 073590.5_07623001_1 - 0.0092 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.23 073590.5_07623001_1 - 0.03 13.6 0.2 0.058 12.7 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III_C PF08541.8 073590.5_07623001_1 - 0.083 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Epimerase PF01370.19 073590.5_07623001_1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_47 PF01532.18 001269460.1_07624001_1 - 7.5e-144 479.9 4.0 1.1e-143 479.4 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 7TM_GPCR_Str PF10326.7 073775.2_07623001_1 - 5.5e-102 341.1 23.2 6.3e-102 340.9 23.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.7 073775.2_07623001_1 - 7.8e-49 166.5 20.7 9.6e-49 166.2 20.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srd PF10317.7 073775.2_07623001_1 - 1.1e-22 80.5 28.0 8.2e-22 77.6 28.0 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srh PF10318.7 073775.2_07623001_1 - 1.1e-18 67.1 22.7 1.5e-18 66.8 22.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh Rhomboid PF01694.20 073775.2_07623001_1 - 1.2 8.9 8.2 0.21 11.4 4.1 1.8 2 0 0 2 2 2 0 Rhomboid family FKBP_C PF00254.26 073796.5_07622001_1 - 1.2e-44 150.4 0.0 7.9e-25 86.9 0.0 2.2 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Citrate_bind PF16114.3 073866.3_07627001_1 - 4.8e-88 293.2 0.1 8.2e-88 292.4 0.1 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Ligase_CoA PF00549.17 073866.3_07627001_1 - 4e-22 78.5 0.2 9.3e-22 77.4 0.1 1.7 2 0 0 2 2 2 1 CoA-ligase Citrate_synt PF00285.19 073866.3_07627001_1 - 2.2e-21 76.2 0.0 7.3e-20 71.2 0.0 2.5 1 1 1 2 2 2 1 Citrate synthase, C-terminal domain CoA_binding PF02629.17 073866.3_07627001_1 - 2.2e-17 63.4 0.0 5.6e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.8 073866.3_07627001_1 - 6.8e-08 32.2 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.4 073866.3_07627001_1 - 0.00063 19.4 0.0 0.0063 16.2 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.4 073866.3_07627001_1 - 0.041 14.2 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain PH PF00169.27 001269564.1_07623001_1 - 0.0027 18.0 0.1 0.0074 16.7 0.1 1.7 1 0 0 1 1 1 1 PH domain Enkurin PF13864.4 001269564.1_07623001_1 - 0.11 12.9 5.4 0.32 11.3 0.1 3.2 3 0 0 3 3 3 0 Calmodulin-binding NRBF2 PF08961.8 073924.3_07622001_1 - 0.61 9.5 1.5 0.85 9.1 1.5 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator NicO PF03824.14 073924.3_07622001_2 - 0.66 9.1 4.7 0.86 8.7 4.7 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein 7tm_1 PF00001.19 001276953.1_07623001_1 - 1.7e-13 50.3 26.5 2.5e-13 49.8 26.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.7 001276953.1_07623001_1 - 6e-09 35.5 27.1 9.3e-09 34.9 27.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw VPS9 PF02204.16 001276953.1_07623001_1 - 0.0072 16.4 0.3 0.018 15.1 0.3 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF898 PF05987.11 001276953.1_07623001_1 - 0.0099 14.8 1.5 0.0099 14.8 1.5 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) 7TM_GPCR_Srsx PF10320.7 001276953.1_07623001_1 - 0.14 11.4 29.9 0.21 10.8 29.9 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF5056 PF16479.3 001276953.1_07623001_1 - 0.46 10.6 3.0 7.8 6.7 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Tmemb_9 PF05434.9 001276953.1_07623001_1 - 0.99 9.1 5.5 0.51 10.0 0.5 2.6 2 1 0 2 2 2 0 TMEM9 Caveolin PF01146.15 001269594.1_07623001_1 - 6e-29 100.5 5.3 8.7e-29 100.0 5.3 1.2 1 0 0 1 1 1 1 Caveolin DUF4491 PF14898.4 001269594.1_07623001_1 - 0.0082 16.4 3.8 0.018 15.3 3.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4491) DUF2207 PF09972.7 001269594.1_07623001_1 - 0.44 9.1 2.7 0.82 8.2 2.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SelP_N PF04592.12 001269594.1_07623001_1 - 5.7 6.1 15.9 11 5.1 15.9 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ly-6_related PF06579.10 171552.3_07622001_1 - 3e-40 137.1 0.6 3.9e-40 136.8 0.6 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein Sec23_helical PF04815.13 171552.3_07622001_1 - 0.031 13.9 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain 7TM_GPCR_Srw PF10324.7 001269729.1_07622001_1 - 1.4e-46 159.1 26.0 3.2e-36 125.1 16.6 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF4579 PF15158.4 001269729.1_07622001_1 - 2.4 7.7 9.4 0.93 9.0 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) FTH PF01827.25 001276970.1_07622001_1 - 4.7e-23 81.5 5.3 4.7e-23 81.5 5.3 1.8 2 0 0 2 2 2 1 FTH domain F-box PF00646.31 001276970.1_07622001_1 - 8.6e-12 44.5 0.0 4.8e-10 38.9 0.0 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.5 001276970.1_07622001_1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Mtc PF03820.15 001029110.2_07622001_1 - 6.4e-118 393.2 0.6 7.2e-118 393.0 0.6 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier MBOAT PF03062.17 001029110.2_07622001_1 - 0.0088 15.3 0.1 0.015 14.6 0.1 1.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family NOD PF06816.11 001029110.2_07622001_2 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 NOTCH protein Hormone_recep PF00104.28 074567.3_07623001_1 - 9.4e-43 146.1 10.1 1.2e-42 145.7 10.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 074567.3_07623001_1 - 1.3e-18 67.1 15.0 2.8e-18 66.0 15.0 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) 7TM_GPCR_Srh PF10318.7 074681.2_07622001_1 - 4e-110 367.4 25.8 4.6e-110 367.3 25.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.7 074681.2_07622001_1 - 4.9e-24 84.9 24.2 6.7e-24 84.5 24.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Srd PF10317.7 074681.2_07622001_1 - 1.2e-15 57.3 24.1 1.4e-15 57.1 24.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.7 074681.2_07622001_1 - 2.7e-14 53.1 22.7 3.5e-14 52.7 22.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.7 074681.2_07622001_1 - 5.9e-06 25.7 14.3 1.1e-05 24.8 14.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Sru PF10322.7 074764.1_07622001_1 - 8.6e-75 251.7 27.8 9.6e-75 251.6 27.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru Ninjurin PF04923.10 074764.1_07622001_1 - 0.0034 17.2 3.1 0.0065 16.3 1.7 2.2 2 0 0 2 2 2 1 Ninjurin DUF1746 PF08508.8 074764.1_07622001_1 - 0.013 15.8 1.4 0.013 15.8 1.4 2.9 3 1 0 3 3 3 0 Fungal domain of unknown function (DUF1746) DUF3283 PF11686.6 074764.1_07622001_1 - 0.13 11.9 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) EIIC-GAT PF03611.12 074764.1_07622001_1 - 1.3 7.9 13.4 0.02 13.9 3.9 2.2 2 1 0 2 2 2 0 PTS system sugar-specific permease component DUF1980 PF09323.8 074764.1_07622001_1 - 8.7 6.1 10.7 6.9 6.4 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) 7TM_GPCR_Str PF10326.7 001356771.1_07623001_1 - 4.3e-87 292.2 23.4 4.9e-87 292.0 23.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.7 001356771.1_07623001_1 - 1.8e-22 80.0 19.8 2e-22 79.8 19.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srh PF10318.7 001356771.1_07623001_1 - 1.5e-12 47.0 3.9 1.5e-12 47.0 3.9 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srd PF10317.7 001356771.1_07623001_1 - 0.0024 17.0 22.1 0.0047 16.0 22.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd DNA_ligase_IV PF11411.6 001356771.1_07623001_1 - 0.039 13.9 0.5 0.078 12.9 0.5 1.5 1 0 0 1 1 1 0 DNA ligase IV Syndecan PF01034.18 001356771.1_07623001_1 - 1.6 8.5 4.3 0.53 10.1 0.2 2.3 2 0 0 2 2 2 0 Syndecan domain PseudoU_synth_1 PF01416.18 074841.6_07623001_1 - 2.5e-11 43.9 0.1 2.7e-09 37.3 0.0 3.1 3 0 0 3 3 3 1 tRNA pseudouridine synthase Lectin_C PF00059.19 001269798.1_07623001_1 - 4.1e-22 78.8 1.8 1.6e-10 41.6 0.6 2.3 2 0 0 2 2 2 2 Lectin C-type domain Vps5 PF09325.8 001269834.1_07623001_1 - 4.3e-18 65.6 19.5 1.9e-17 63.5 12.7 2.8 2 1 0 2 2 2 1 Vps5 C terminal like PX PF00787.22 001269834.1_07623001_1 - 3.5e-17 62.3 1.3 1.4e-16 60.4 0.4 2.4 2 0 0 2 2 2 1 PX domain FTH PF01827.25 075129.3_07622001_1 - 6.5e-39 132.8 0.5 1.1e-38 132.2 0.5 1.3 1 0 0 1 1 1 1 FTH domain F-box PF00646.31 075129.3_07622001_1 - 1.1e-10 41.0 0.1 2.1e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 075129.3_07622001_1 - 0.00024 20.8 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like Hormone_recep PF00104.28 075272.2_07623001_1 - 5.1e-71 238.4 6.6 9.8e-71 237.5 6.6 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 075272.2_07623001_1 - 4e-17 62.3 13.0 7.4e-17 61.4 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GST_N PF02798.18 075272.2_07623001_1 - 0.0095 16.1 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Asp PF00026.21 171585.1_07623001_1 - 4.8e-71 239.6 0.4 5.7e-71 239.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 171585.1_07623001_1 - 1.6e-09 38.1 0.8 7e-08 32.8 0.4 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal SK_channel PF03530.12 001129366.2_07625001_1 - 6.2e-39 132.4 2.2 6.2e-39 132.4 2.2 1.7 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.14 001129366.2_07625001_1 - 1e-28 99.3 3.8 2.9e-28 97.8 3.8 1.8 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.14 001129366.2_07625001_1 - 7.6e-12 44.9 4.4 7.6e-12 44.9 4.4 1.9 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.24 001129366.2_07625001_1 - 0.0042 16.8 1.6 0.0064 16.2 0.1 2.1 2 0 0 2 2 2 1 Ligand-gated ion channel DUF1461 PF07314.9 001129366.2_07625001_1 - 0.47 10.2 5.9 0.051 13.4 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) FTH PF01827.25 075431.2_07622001_1 - 6.2e-30 103.7 0.7 1.8e-29 102.3 0.2 2.0 2 1 0 2 2 2 1 FTH domain F-box PF00646.31 075431.2_07622001_1 - 2.1e-10 40.1 0.8 5.2e-10 38.8 0.8 1.7 1 0 0 1 1 1 1 F-box domain DUF3365 PF11845.6 075510.4_07621001_1 - 0.017 15.3 1.6 0.02 15.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Joubert PF15392.4 075510.4_07621001_1 - 0.039 13.5 0.5 0.044 13.4 0.5 1.0 1 0 0 1 1 1 0 Joubert syndrome-associated Ground-like PF04155.16 001270027.1_07623001_1 - 1.3e-18 67.3 1.2 2e-18 66.7 0.3 1.8 2 0 0 2 2 2 1 Ground-like domain PID PF00640.21 001028927.1_07624001_1 - 3.3e-22 78.9 0.0 6.5e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.4 001028927.1_07624001_1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) NumbF PF06311.10 001028927.1_07624001_1 - 0.00042 20.7 0.1 0.0022 18.4 0.1 2.2 1 0 0 1 1 1 1 NUMB domain PTB PF08416.11 001028927.1_07624001_1 - 0.0087 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain adh_short PF00106.23 132472.1_07622120_2 - 1.6e-23 83.0 0.0 1.7e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.4 132472.1_07622120_2 - 2.6e-15 56.5 0.0 6.4e-15 55.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 132472.1_07622120_2 - 1.3e-11 44.6 0.0 1.8e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 KR domain UL40 PF10682.7 132472.1_07622120_2 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 7TM_GPCR_Sri PF10327.7 132479.1_07622120_1 - 2.9e-109 364.8 38.7 1.4e-64 218.0 20.3 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Srh PF10318.7 132479.1_07622120_1 - 4.1e-30 104.7 38.4 5.8e-30 104.2 38.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srd PF10317.7 132479.1_07622120_1 - 3.4e-06 26.3 39.7 4.7e-06 25.9 39.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Str PF10326.7 132479.1_07622120_1 - 0.0016 17.8 37.9 0.0041 16.4 37.9 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str DUF2269 PF10027.7 132479.1_07622120_1 - 0.42 10.5 15.1 0.088 12.7 4.4 2.8 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2269) DUF2197 PF09963.7 132480.1_07622120_2 - 0.05 13.7 0.1 0.086 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) Coatomer_b_Cpla PF14806.4 151566.1_07624120_1 - 0.055 13.3 0.0 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform LRR_4 PF12799.5 132491.1_07623120_1 - 9.1e-06 25.8 15.6 0.004 17.4 4.2 4.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 132491.1_07623120_1 - 0.043 13.4 7.7 0.12 12.1 2.3 3.3 2 1 0 2 2 2 0 Leucine rich repeat Hormone_recep PF00104.28 132512.1_07623120_2 - 3.1e-18 66.0 8.5 3.1e-18 66.0 8.5 1.7 1 1 1 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 132512.1_07623120_2 - 4.5e-09 36.5 6.0 9.4e-09 35.5 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Phage_connect_1 PF05135.11 132518.1_07622120_1 - 0.096 13.1 1.0 0.18 12.2 1.0 1.4 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein Lipase_3 PF01764.23 132522.1_07624120_3 - 2.9e-27 95.1 0.0 4.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.6 132522.1_07624120_3 - 0.037 13.4 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.23 132523.1_07622120_3 - 4.6e-32 110.7 0.0 6.3e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.6 132523.1_07622120_3 - 0.0012 18.3 0.1 0.01 15.2 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.12 132523.1_07622120_3 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Glyco_transf_92 PF01697.25 132525.1_07623120_2 - 2.6e-43 148.4 3.4 3.5e-43 148.0 3.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.4 132525.1_07623120_2 - 0.13 12.6 0.7 0.36 11.3 0.7 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Choline_kinase PF01633.18 132528.1_07623120_1 - 3.8e-57 193.2 0.0 5.2e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.21 132528.1_07623120_1 - 1.3e-08 35.0 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.18 132528.1_07623120_1 - 0.008 15.4 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Hormone_recep PF00104.28 133581.1_07623120_3 - 3.2e-54 183.6 5.7 4.6e-54 183.0 5.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 133581.1_07623120_3 - 1.2e-11 44.8 11.9 2.1e-11 43.9 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) MFS_1 PF07690.14 133589.1_07621120_1 - 0.004 16.0 0.1 0.0044 15.9 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily 7TM_GPCR_Srd PF10317.7 133596.1_07621120_1 - 5e-08 32.4 0.1 6e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Peptidase_S66 PF02016.13 133596.1_07621120_1 - 0.098 11.9 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 LD-carboxypeptidase 7TM_GPCR_Srd PF10317.7 133596.1_07621120_2 - 6.9e-07 28.6 0.0 9.5e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Na_Pi_cotrans PF02690.13 133596.1_07621120_2 - 0.079 12.9 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Na+/Pi-cotransporter Recep_L_domain PF01030.22 133600.1_07622120_2 - 1.4e-06 28.3 1.3 0.0039 17.1 0.4 2.7 2 1 0 2 2 2 2 Receptor L domain Recep_L_domain PF01030.22 133600.1_07622120_3 - 3.2e-05 23.9 4.1 5.1e-05 23.2 4.1 1.3 1 0 0 1 1 1 1 Receptor L domain Pentapeptide_4 PF13599.4 133600.1_07622120_3 - 0.1 12.6 0.5 1.7 8.7 0.4 2.5 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) 7TM_GPCR_Srd PF10317.7 133605.1_07621120_1 - 5e-08 32.4 0.1 6e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Peptidase_S66 PF02016.13 133605.1_07621120_1 - 0.098 11.9 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 LD-carboxypeptidase 7TM_GPCR_Srd PF10317.7 133605.1_07621120_2 - 6.9e-07 28.6 0.0 9.5e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Na_Pi_cotrans PF02690.13 133605.1_07621120_2 - 0.079 12.9 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Na+/Pi-cotransporter DSL PF01414.17 134545.1_07623120_1 - 8.7e-15 54.5 4.6 8.7e-15 54.5 4.6 4.6 3 2 1 4 4 4 1 Delta serrate ligand EGF PF00008.25 134545.1_07623120_1 - 9.2e-07 28.9 16.3 0.00015 21.9 4.2 7.4 7 0 0 7 7 7 3 EGF-like domain EGF_2 PF07974.11 134545.1_07623120_1 - 5.2e-06 26.6 90.9 0.01 16.1 14.1 7.9 7 1 0 7 7 7 5 EGF-like domain hEGF PF12661.5 134545.1_07623120_1 - 0.028 15.0 58.6 0.031 14.8 4.4 7.4 8 0 0 8 8 8 0 Human growth factor-like EGF Laminin_EGF PF00053.22 134545.1_07623120_1 - 2.1 8.4 70.8 0.39 10.8 13.8 6.6 2 2 4 6 6 6 0 Laminin EGF domain zf-C4 PF00105.16 136393.1_07623120_1 - 1.2e-15 57.5 9.6 2.2e-15 56.7 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 136393.1_07623120_3 - 1.4e-06 27.9 0.0 2.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor 7TM_GPCR_Srbc PF10316.7 136392.1_07622120_1 - 5.5e-11 42.4 2.6 9.4e-11 41.6 2.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srbc PF10316.7 136392.1_07622120_2 - 5.6e-14 52.2 1.7 8.1e-14 51.6 1.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srbc PF10316.7 136392.1_07622120_3 - 8.2e-38 130.3 17.1 1.3e-37 129.7 17.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc AAA_28 PF13521.4 138515.1_07624120_3 - 3.6e-20 72.7 0.0 5.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.15 138515.1_07624120_3 - 0.0081 15.7 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 Thymidylate kinase DAP3 PF10236.7 138515.1_07624120_3 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_33 PF13671.4 138515.1_07624120_3 - 0.043 13.8 0.1 3.2 7.8 0.1 2.3 1 1 0 2 2 2 0 AAA domain KTI12 PF08433.8 138515.1_07624120_3 - 0.06 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Hormone_recep PF00104.28 138494.1_07623120_1 - 1.2e-20 73.9 0.1 1.6e-20 73.4 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor CPL PF08144.9 138494.1_07623120_1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 CPL (NUC119) domain Creatinase_N_2 PF16189.3 138522.1_07627120_1 - 2.4e-33 115.3 0.1 3.5e-30 105.1 0.1 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.22 138522.1_07627120_1 - 2e-25 89.6 0.1 3e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.3 138522.1_07627120_1 - 1.9e-21 75.7 0.2 5.1e-21 74.4 0.2 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.16 138522.1_07627120_1 - 1.1e-12 48.6 0.0 5.8e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain 7TM_GPCR_Srh PF10318.7 138496.1_07622120_1 - 2e-14 53.2 1.5 2e-14 53.2 1.5 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srh PF10318.7 138496.1_07622120_2 - 7.4e-71 238.5 29.7 1.3e-70 237.7 29.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.7 138496.1_07622120_2 - 3.6e-15 55.8 24.3 5.2e-15 55.3 24.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri 7TM_GPCR_Str PF10326.7 138496.1_07622120_2 - 7.8e-08 31.9 29.6 2.8e-07 30.1 29.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srd PF10317.7 138496.1_07622120_2 - 9.8e-06 24.8 29.0 1.9e-05 23.9 29.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srj PF10319.7 138496.1_07622120_2 - 0.022 14.0 25.9 0.053 12.7 25.9 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj 7tm_1 PF00001.19 138496.1_07622120_2 - 5.1 6.1 16.0 8.5 5.4 16.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) tRNA_Me_trans PF03054.14 138493.1_07621120_1 - 0.17 10.5 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase DUF1011 PF06237.10 138524.1_07623120_1 - 2.8e-28 98.0 10.2 6.2e-28 96.9 10.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1011) Methyltransf_31 PF13847.4 000460.1_07621120_2 - 0.015 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4725 PF15854.3 068777.1_07621120_2 - 0.0074 16.4 0.3 0.011 15.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4725) adh_short PF00106.23 136375.1_07624120_1 - 2.6e-20 72.6 0.0 1.1e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 136375.1_07624120_1 - 2.2e-08 33.8 0.0 3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 136375.1_07624120_1 - 4.4e-08 33.1 0.0 6.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 KR domain F-box PF00646.31 136375.1_07624120_3 - 0.025 14.3 0.0 0.085 12.6 0.0 1.9 1 0 0 1 1 1 0 F-box domain AAA_10 PF12846.5 068857.1_07621120_3 - 0.084 11.6 0.0 0.093 11.5 0.0 1.0 1 0 0 1 1 1 0 AAA-like domain TMEM126 PF07114.9 068860.1_07621120_2 - 0.046 13.0 0.1 0.048 12.9 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 126 Acyl_transf_3 PF01757.20 136394.1_07625120_3 - 1.5e-06 27.4 37.7 1.5e-06 27.4 37.7 1.4 2 0 0 2 2 2 1 Acyltransferase family DUF1240 PF06836.10 136394.1_07625120_3 - 0.36 11.2 6.7 0.25 11.7 2.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DUF4190 PF13828.4 136394.1_07625120_3 - 0.39 10.4 7.4 0.047 13.3 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) AAA PF00004.27 136364.1_07624120_2 - 5.9e-40 136.6 0.1 1.3e-39 135.5 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.10 136364.1_07624120_2 - 5.9e-06 25.6 0.0 1.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.12 136364.1_07624120_2 - 1.5e-05 25.1 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 136364.1_07624120_2 - 0.00014 21.7 0.2 0.0023 17.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.8 136364.1_07624120_2 - 0.00056 19.7 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.4 136364.1_07624120_2 - 0.0064 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.4 136364.1_07624120_2 - 0.007 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.4 136364.1_07624120_2 - 0.0096 16.1 0.2 0.24 11.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.11 136364.1_07624120_2 - 0.011 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.15 136364.1_07624120_2 - 0.03 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.24 136364.1_07624120_2 - 0.03 13.9 0.0 0.71 9.4 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.4 136364.1_07624120_2 - 0.032 14.5 0.2 0.88 9.8 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.19 136364.1_07624120_2 - 0.038 13.2 0.7 0.077 12.2 0.1 1.7 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.4 136364.1_07624120_2 - 0.099 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.25 136364.1_07624120_2 - 0.11 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter G-patch PF01585.21 138502.1_07624120_2 - 8.4e-12 44.7 0.5 8.4e-12 44.7 0.5 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.5 138502.1_07624120_2 - 0.053 13.5 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 G-patch domain Smg4_UPF3 PF03467.13 138502.1_07624120_3 - 0.046 13.6 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Smg-4/UPF3 family RRM_1 PF00076.20 138502.1_07624120_3 - 0.057 13.1 0.1 4.9 6.9 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1679 PF07914.9 131696.1_07623120_1 - 1.6e-60 205.0 0.1 2.1e-60 204.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF1679 PF07914.9 131696.1_07623120_3 - 2e-76 257.4 0.7 2.4e-76 257.1 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.18 131696.1_07623120_3 - 3.9e-16 59.1 0.0 7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.21 131696.1_07623120_3 - 2.9e-10 40.4 0.0 3.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.18 131696.1_07623120_3 - 0.0074 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Sulfate_transp PF00916.18 069213.1_07624120_3 - 3.1e-107 358.5 18.8 3.9e-107 358.2 18.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 069213.1_07624120_3 - 2.7e-16 59.1 0.0 4.5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.4 069213.1_07624120_3 - 0.029 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 STAS domain GTP_EFTU PF00009.25 002401.1_07625120_3 - 1.8e-31 109.1 3.0 1.7e-29 102.6 3.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.6 002401.1_07625120_3 - 2.2e-26 91.9 0.2 2.2e-26 91.9 0.2 2.3 3 0 0 3 3 3 1 Translation-initiation factor 2 MMR_HSR1 PF01926.21 002401.1_07625120_3 - 7.7e-11 42.0 0.2 2.1e-10 40.6 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.16 002401.1_07625120_3 - 6.6e-06 25.6 0.4 4.2e-05 23.0 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.7 002401.1_07625120_3 - 0.00015 21.4 0.1 0.00056 19.6 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.4 002401.1_07625120_3 - 0.00034 20.1 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.14 002401.1_07625120_3 - 0.00045 20.0 1.7 0.11 12.2 0.3 2.4 1 1 1 2 2 2 2 Protein of unknown function, DUF258 Arf PF00025.19 002401.1_07625120_3 - 0.00073 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 002401.1_07625120_3 - 0.00076 18.8 0.0 0.0035 16.7 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.11 002401.1_07625120_3 - 0.0086 16.2 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.21 002401.1_07625120_3 - 0.012 15.6 0.4 3.1 7.7 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_23 PF13476.4 002401.1_07625120_3 - 0.019 15.4 0.7 0.81 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain BDHCT_assoc PF16204.3 069237.1_07621120_3 - 0.1 12.2 0.7 0.12 11.9 0.7 1.0 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein VWC PF00093.16 132530.1_07626120_1 - 0.00011 22.3 4.8 0.00011 22.3 4.8 5.8 2 1 3 5 5 5 2 von Willebrand factor type C domain VWC PF00093.16 132530.1_07626120_3 - 1.4e-21 76.4 114.4 2.1e-09 37.4 14.4 9.2 8 1 0 8 8 8 5 von Willebrand factor type C domain Antistasin PF02822.12 132530.1_07626120_3 - 8.2e-13 48.6 42.6 2.8e-06 27.7 9.7 10.0 12 1 0 12 12 12 3 Antistasin family Pacifastin_I PF05375.11 132530.1_07626120_3 - 0.0043 16.6 6.2 0.0043 16.6 6.2 8.0 8 0 0 8 8 8 5 Pacifastin inhibitor (LCMII) TILa PF12714.5 132530.1_07626120_3 - 0.013 15.3 8.3 0.013 15.3 8.3 9.2 7 2 4 11 11 11 0 TILa domain DUF4692 PF15763.3 132530.1_07626120_3 - 0.036 14.4 0.3 0.082 13.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4692) Rifin_STEVOR PF02009.14 132530.1_07626120_3 - 1.4 8.6 0.0 1.4 8.6 0.0 3.7 3 1 0 3 3 3 0 Rifin/stevor family Cadherin_C_2 PF16492.3 132530.1_07626120_3 - 2.3 8.9 4.7 1.6 9.5 1.2 2.6 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal VWC PF00093.16 132531.1_07625120_1 - 8.3e-20 70.7 92.5 1.7e-09 37.7 14.4 11.0 6 2 4 10 10 10 5 von Willebrand factor type C domain Antistasin PF02822.12 132531.1_07625120_1 - 2.9e-13 50.0 42.6 2.2e-06 28.0 9.7 11.9 13 3 0 13 13 13 3 Antistasin family P33MONOX PF15302.4 069324.1_07622120_1 - 0.082 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase Chorismate_bind PF00425.16 069341.1_07621120_2 - 0.0068 15.9 0.1 0.0083 15.6 0.1 1.0 1 0 0 1 1 1 1 chorismate binding enzyme HTH_Tnp_Tc3_1 PF11427.6 069411.1_07621120_3 - 0.98 9.2 4.4 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Tc3 transposase INCENP_N PF12178.6 069542.1_07621120_3 - 0.092 12.5 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal ANF_receptor PF01094.26 132532.1_07627120_1 - 7.6e-09 35.0 0.1 1.1e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region CGGC PF08821.9 132532.1_07627120_1 - 0.096 12.7 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 CGGC domain RELT PF12606.6 132532.1_07627120_1 - 0.66 9.3 5.7 66 2.9 0.0 2.7 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Guanylate_cyc PF00211.18 132532.1_07627120_3 - 9.2e-45 152.4 0.0 1.4e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.15 132532.1_07627120_3 - 1.1e-14 54.2 0.1 1.7e-13 50.3 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 132532.1_07627120_3 - 2.9e-12 46.4 0.3 9.4e-12 44.7 0.3 1.8 1 1 0 1 1 1 1 Protein kinase domain HNOBA PF07701.12 132532.1_07627120_3 - 0.0003 20.2 0.3 0.0003 20.2 0.3 2.0 2 0 0 2 2 2 1 Heme NO binding associated Sre PF03125.16 003167.3_07624120_1 - 0.0011 18.1 13.3 0.004 16.2 13.3 1.9 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor Cyt-b5 PF00173.26 003167.3_07624120_3 - 1.4e-20 73.0 0.0 2.9e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sre PF03125.16 003167.3_07624120_3 - 0.00013 21.2 0.5 0.00021 20.4 0.5 1.3 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor UDPGT PF00201.16 145830.1_07625120_3 - 5e-28 98.0 0.1 6.5e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 145830.1_07625120_3 - 7.8e-05 22.6 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain 7TM_GPCR_Srx PF10328.7 136387.1_07622120_1 - 2.6e-13 49.8 7.4 4.6e-13 49.0 7.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srx PF10328.7 136387.1_07622120_2 - 1.2e-27 96.8 12.6 1.4e-27 96.6 12.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CUB_2 PF02408.18 069914.1_07624120_1 - 7.9e-06 25.5 0.3 2.3e-05 24.0 0.3 1.8 1 0 0 1 1 1 1 CUB-like domain WD40 PF00400.30 003169.1_07624120_1 - 1.1e-47 158.9 34.1 5.2e-08 33.3 0.6 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 003169.1_07624120_1 - 2e-13 50.3 6.3 0.0019 18.3 0.2 6.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 003169.1_07624120_1 - 3.6e-08 32.4 14.4 0.021 13.3 0.1 6.3 2 1 5 7 7 7 4 Nucleoporin Nup120/160 F-box-like PF12937.5 003169.1_07624120_1 - 1.3e-06 28.1 0.0 2.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 003169.1_07624120_1 - 1.1e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain PRANC PF09372.8 003169.1_07624120_1 - 0.028 14.6 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 PRANC domain RAG2_PHD PF13341.4 003169.1_07624120_1 - 0.099 12.6 0.2 3.5 7.6 0.0 2.8 2 0 0 2 2 2 0 RAG2 PHD domain AsnC_trans_reg PF01037.19 003169.1_07624120_1 - 0.19 11.6 1.4 86 3.1 0.0 4.1 4 0 0 4 4 4 0 Lrp/AsnC ligand binding domain PQQ_3 PF13570.4 003169.1_07624120_1 - 0.42 11.0 2.0 4.8 7.7 0.1 3.3 3 0 0 3 3 3 0 PQQ-like domain ELM2 PF01448.22 136374.1_07623120_3 - 0.0027 18.3 0.2 0.0076 16.9 0.2 1.8 1 0 0 1 1 1 1 ELM2 domain SRP_TPR_like PF17004.3 136374.1_07623120_3 - 0.029 14.2 0.1 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 Putative TPR-like repeat Hormone_recep PF00104.28 136353.1_07623120_3 - 7.2e-19 68.1 3.3 1.1e-18 67.5 3.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 136353.1_07623120_3 - 3.9e-11 43.1 14.6 3.9e-11 43.1 14.6 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Pox_A31 PF05771.9 102108.1_07621120_1 - 0.031 14.2 0.1 0.031 14.2 0.1 1.4 2 0 0 2 2 2 0 Poxvirus A31 protein FTH PF01827.25 070114.1_07626120_1 - 9.2e-32 109.7 2.9 2.2e-18 66.3 0.1 2.8 2 0 0 2 2 2 2 FTH domain F-box PF00646.31 070114.1_07626120_1 - 2e-06 27.4 1.3 2.4e-05 23.9 0.1 3.0 3 0 0 3 3 3 1 F-box domain FTH PF01827.25 070114.1_07626120_2 - 4.2e-19 68.6 2.4 7.3e-19 67.9 2.4 1.3 1 0 0 1 1 1 1 FTH domain Cornifin PF02389.13 070119.1_07621120_1 - 0.0085 16.2 0.6 0.0087 16.1 0.6 1.0 1 0 0 1 1 1 1 Cornifin (SPRR) family Cir_N PF10197.7 070119.1_07621120_1 - 0.31 11.1 9.9 4.6e+02 1.0 0.0 6.9 8 0 0 8 8 8 0 N-terminal domain of CBF1 interacting co-repressor CIR Cornifin PF02389.13 070119.1_07621120_2 - 0.013 15.6 0.9 0.013 15.6 0.9 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family Cir_N PF10197.7 070119.1_07621120_2 - 6.9 6.8 12.8 4.5e+02 1.0 0.0 6.6 8 0 0 8 8 8 0 N-terminal domain of CBF1 interacting co-repressor CIR Cornifin PF02389.13 070119.1_07621120_3 - 0.007 16.4 0.7 0.0073 16.4 0.7 1.0 1 0 0 1 1 1 1 Cornifin (SPRR) family Cir_N PF10197.7 070119.1_07621120_3 - 0.28 11.3 9.9 4.5e+02 1.0 0.0 6.9 8 0 0 8 8 8 0 N-terminal domain of CBF1 interacting co-repressor CIR Dicty_REP PF05086.10 002407.1_07624120_3 - 0.03 12.2 3.6 0.04 11.8 3.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Menin PF05053.11 002407.1_07624120_3 - 0.035 12.4 1.6 0.046 11.9 1.6 1.1 1 0 0 1 1 1 0 Menin Cupin_4 PF08007.10 002407.1_07624120_3 - 0.045 13.1 1.0 0.066 12.5 0.0 1.7 2 0 0 2 2 2 0 Cupin superfamily protein Inhibitor_I29 PF08246.10 070167.1_07623120_1 - 2.3e-08 34.2 5.2 4.9e-08 33.2 5.2 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.21 070167.1_07623120_1 - 3.1e-07 30.6 0.1 5e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.21 070167.1_07623120_3 - 6.6e-30 104.7 0.2 1.1e-29 104.0 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease TIL PF01826.15 070184.1_07626120_1 - 6.6e-06 26.1 17.2 6.6e-06 26.1 17.2 4.0 3 1 1 4 4 4 2 Trypsin Inhibitor like cysteine rich domain TIL PF01826.15 070184.1_07626120_3 - 2.5e-18 65.9 89.7 1.1e-08 35.0 18.4 7.4 6 1 1 7 7 7 4 Trypsin Inhibitor like cysteine rich domain Sialidase_penC PF12135.6 070186.1_07621120_1 - 2.7 7.7 7.8 23 4.7 0.0 4.1 4 1 0 4 4 4 0 Sialidase enzyme penultimate C terminal domain F-box PF00646.31 102122.1_07622120_1 - 0.00012 21.7 0.3 0.00024 20.8 0.3 1.5 1 0 0 1 1 1 1 F-box domain FBA_2 PF07735.15 102122.1_07622120_3 - 1.2e-11 44.5 3.0 2.8e-11 43.3 3.0 1.7 1 0 0 1 1 1 1 F-box associated Shisa PF13908.4 070283.1_07621120_3 - 0.00064 19.9 0.2 0.00074 19.7 0.2 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator FAM163 PF15069.4 070283.1_07621120_3 - 0.0066 16.8 0.3 0.0083 16.5 0.3 1.1 1 0 0 1 1 1 1 FAM163 family DUF4713 PF15831.3 070283.1_07621120_3 - 3.7 7.9 10.1 5.9 7.3 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Ribosomal_L2 PF00181.21 102132.1_07623120_1 - 6.6e-08 32.3 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.16 102132.1_07623120_3 - 1e-06 28.9 0.1 1.9e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain FTH PF01827.25 070290.1_07622120_2 - 5.6e-09 35.8 7.1 2.5e-08 33.7 5.6 2.5 1 1 1 2 2 2 1 FTH domain DUF3213 PF11491.6 070290.1_07622120_2 - 0.061 13.4 1.8 2.6 8.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3213) Peptidase_M28 PF04389.15 075684.5_07625001_1 - 4.1e-22 78.7 0.0 1.1e-21 77.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.13 075684.5_07625001_1 - 1.2e-18 67.3 0.0 2.6e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.20 075684.5_07625001_1 - 2.2e-13 50.0 0.0 6.4e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.13 075684.5_07625001_1 - 0.002 17.5 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.26 075684.5_07625001_1 - 0.0046 16.6 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2207 PF09972.7 075791.4_07624001_1 - 0.05 12.2 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cytochrom_B_N_2 PF13631.4 075791.4_07624001_1 - 0.05 13.5 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB SARAF PF06682.10 075791.4_07624001_1 - 0.59 9.6 6.4 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis LIM PF00412.20 001270052.1_07622001_1 - 1.6e-21 76.2 30.7 1.2e-10 41.3 7.6 2.2 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.27 001270052.1_07622001_1 - 2.1e-17 62.6 6.1 4.6e-17 61.4 6.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001270052.1_07622001_1 - 8.7e-06 25.4 0.1 1.9e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Lamp PF01299.15 075814.3_07622001_1 - 5.4e-23 81.9 0.7 2.1e-22 80.0 0.7 1.8 1 1 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Sedlin_N PF04628.11 075871.5_07621001_1 - 4e-47 159.5 0.3 4.4e-47 159.3 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.10 075871.5_07621001_1 - 2.7e-07 30.5 0.1 3.9e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Sybindin-like family FBA_2 PF07735.15 001322617.1_07623001_1 - 3.4e-18 65.4 1.0 1.3e-17 63.6 1.0 2.1 1 0 0 1 1 1 1 F-box associated F-box PF00646.31 001322617.1_07623001_1 - 3.5e-08 33.0 0.8 4.5e-07 29.5 0.2 2.7 2 0 0 2 2 2 1 F-box domain Claudin_2 PF13903.4 001029822.3_07622001_1 - 7.3e-09 35.5 6.2 1.1e-08 35.0 6.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.18 001029822.3_07622001_1 - 8.4e-08 32.1 6.3 3e-07 30.3 6.3 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.10 001029822.3_07622001_1 - 0.026 13.9 6.8 0.044 13.1 6.8 1.5 1 1 0 1 1 1 0 Clc-like UbiA PF01040.16 001029822.3_07622001_1 - 0.1 11.7 6.6 0.47 9.6 3.2 2.8 2 1 0 2 2 2 0 UbiA prenyltransferase family DUF1065 PF06358.9 001029822.3_07622001_1 - 0.14 11.9 0.9 0.45 10.3 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1065) Claudin_3 PF06653.9 001029822.3_07622001_1 - 2.8 7.7 9.7 12 5.7 9.7 2.2 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF1218 PF06749.10 001029822.3_07622001_1 - 3 8.3 11.9 1.6 9.2 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Toxin_21 PF08091.9 001029822.3_07622001_2 - 0.29 11.0 7.4 0.074 12.9 3.2 2.2 2 0 0 2 2 2 0 Spider insecticidal peptide Choline_transpo PF04515.10 171686.5_07625001_1 - 4e-100 335.0 30.6 4e-100 335.0 30.6 3.1 3 1 0 3 3 3 1 Plasma-membrane choline transporter Pox_EPC_I2-L1 PF12575.6 171686.5_07625001_1 - 0.007 16.4 0.7 0.007 16.4 0.7 4.5 6 0 0 6 6 6 1 Poxvirus entry protein complex L1 and I2 GSHPx PF00255.17 001129699.3_07622001_1 - 2.4e-33 113.8 0.0 3.4e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 001129699.3_07622001_1 - 0.00044 20.0 0.0 0.0013 18.5 0.0 1.7 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.8 001129699.3_07622001_1 - 0.00091 18.8 0.0 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 Redoxin XendoU PF09412.8 076990.4_07624001_1 - 9.8e-109 362.5 0.5 2e-62 210.7 0.1 2.0 2 0 0 2 2 2 2 Endoribonuclease XendoU Troponin PF00992.18 077087.6_07622001_1 - 3.2e-42 143.9 11.0 3.2e-42 143.9 11.0 2.8 4 0 0 4 4 4 1 Troponin Sin3_corepress PF08295.10 077087.6_07622001_1 - 0.0068 16.3 0.3 0.02 14.8 0.3 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Spc24 PF08286.9 077087.6_07622001_1 - 8.1 6.6 10.6 0.38 10.9 0.4 2.9 2 2 0 2 2 2 0 Spc24 subunit of Ndc80 Gal-bind_lectin PF00337.20 077248.4_07622001_1 - 6.1e-32 109.8 0.8 7.7e-32 109.5 0.8 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Yippee-Mis18 PF03226.12 077458.5_07621001_1 - 2.7e-06 27.4 0.1 4.3e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PHD PF00628.27 077656.1_07623001_1 - 5.6e-08 32.4 5.4 1.2e-07 31.3 5.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.4 077656.1_07623001_1 - 2.3e-05 23.7 0.5 5.3e-05 22.5 0.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.4 077656.1_07623001_1 - 0.029 13.9 2.1 0.1 12.1 2.0 2.0 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H_2 PF13832.4 077656.1_07623001_1 - 0.076 13.0 3.3 0.19 11.8 3.3 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.4 077656.1_07623001_1 - 0.082 13.0 2.4 0.23 11.6 2.4 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain 7tm_1 PF00001.19 001313375.1_07623001_1 - 4.5e-41 140.7 12.6 7.8e-41 139.9 12.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001313375.1_07623001_1 - 2.7e-11 43.2 19.0 4e-11 42.6 19.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001313375.1_07623001_1 - 0.00034 19.9 18.4 0.00071 18.8 18.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1772 PF08592.9 001313375.1_07623001_1 - 0.019 15.2 3.2 0.08 13.1 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF2116 PF09889.7 001313375.1_07623001_1 - 0.026 14.4 3.0 0.47 10.3 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PX PF00787.22 001083293.2_07624001_1 - 4.2e-13 49.1 0.5 4.2e-13 49.1 0.5 1.9 2 0 0 2 2 2 1 PX domain ENTH PF01417.18 078058.3_07623001_1 - 4.9e-46 155.7 0.0 1e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.14 078058.3_07623001_1 - 4.5e-10 38.8 0.3 7.5e-10 38.1 0.3 1.5 1 1 0 1 1 1 1 ANTH domain VHS PF00790.17 078058.3_07623001_1 - 0.0029 17.3 0.2 0.0046 16.7 0.2 1.3 1 0 0 1 1 1 1 VHS domain UIM PF02809.18 078058.3_07623001_1 - 4.2 7.4 17.2 3.6 7.6 5.8 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif 7TM_GPCR_Srw PF10324.7 078154.3_07624001_1 - 6.1e-19 68.3 21.7 5.7e-13 48.7 12.6 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.19 078154.3_07624001_1 - 1.6e-14 53.6 20.3 6.2e-14 51.7 20.3 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Collagen PF01391.16 078216.1_07623001_1 - 9.2e-19 66.8 100.9 0.58 9.8 21.4 4.0 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.15 078216.1_07623001_1 - 1e-15 57.4 0.8 1.3e-15 57.0 0.8 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Pr_beta_C PF12465.6 078216.1_07623001_2 - 0.1 11.9 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Proteasome beta subunits C terminal Hist_deacetyl PF00850.17 001270349.1_07626001_1 - 3.2e-81 273.0 0.1 5.8e-81 272.2 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain 7tm_1 PF00001.19 078378.2_07623001_1 - 3.2e-37 128.1 14.1 4.3e-37 127.7 14.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 078378.2_07623001_1 - 4.6e-08 32.6 13.4 4.9e-08 32.5 9.6 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 078378.2_07623001_1 - 1.4e-05 24.9 11.2 1.4e-05 24.9 11.2 1.8 2 0 0 2 2 2 1 Olfactory receptor DUF1049 PF06305.9 078378.2_07623001_1 - 0.0046 16.6 0.3 0.0046 16.6 0.3 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1049) 7TM_GPCR_Srx PF10328.7 078378.2_07623001_1 - 0.06 12.5 18.1 0.0088 15.3 13.6 1.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF1418 PF07214.10 078378.2_07623001_1 - 0.063 13.0 0.2 0.063 13.0 0.2 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1418) DUF621 PF04789.13 078378.2_07623001_1 - 0.13 11.3 15.2 0.21 10.6 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Involucrin_N PF10583.7 078378.2_07623001_2 - 0.17 12.4 2.0 0.33 11.4 2.0 1.4 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus DctQ PF04290.10 001047826.1_07621001_1 - 0.019 14.8 3.1 0.023 14.5 3.1 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component 7tm_1 PF00001.19 001047826.1_07621001_1 - 0.035 13.2 0.4 0.042 12.9 0.4 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) zf-DHHC PF01529.18 001047826.1_07621001_1 - 0.36 10.8 3.2 0.69 9.9 3.2 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF347 PF03988.10 001047826.1_07621001_1 - 6.7 6.9 9.3 14 5.8 0.4 2.4 1 1 1 2 2 2 0 Repeat of Unknown Function (DUF347) ULD PF16534.3 147826.1_07625120_1 - 3e-31 107.6 0.1 4.9e-31 106.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB Homeobox PF00046.27 147826.1_07625120_2 - 1.3e-11 44.0 7.7 2.7e-09 36.6 0.5 2.8 2 0 0 2 2 2 2 Homeobox domain Homez PF11569.6 147826.1_07625120_2 - 0.0066 15.8 0.4 0.1 12.0 0.2 2.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.9 147826.1_07625120_2 - 1.7 8.5 4.3 5.9 6.7 0.3 3.2 3 0 0 3 3 3 0 Homeobox KN domain TPR_1 PF00515.26 136377.1_07624120_1 - 1.7e-06 27.5 1.1 0.0018 17.9 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.4 136377.1_07624120_1 - 1.9e-05 24.7 0.1 3.2e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.15 136377.1_07624120_1 - 5.5e-05 22.8 0.6 0.21 11.6 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.4 136377.1_07624120_1 - 0.033 14.1 0.2 0.89 9.6 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.4 136377.1_07624120_1 - 0.051 13.7 1.0 2.7 8.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.4 136377.1_07624120_1 - 0.23 11.0 0.1 2.1 8.0 0.0 2.2 1 1 1 2 2 2 0 TPR repeat GoLoco PF02188.15 136377.1_07624120_3 - 1e-33 114.2 15.4 4e-10 38.8 0.7 4.4 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.4 136377.1_07624120_3 - 4.6e-20 71.6 26.7 3.1e-07 30.5 1.2 4.0 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.26 136377.1_07624120_3 - 2.5e-12 45.9 21.9 0.031 14.0 0.2 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.4 136377.1_07624120_3 - 3.7e-09 35.8 11.2 0.0091 15.8 0.2 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.15 136377.1_07624120_3 - 4e-05 23.3 15.7 0.77 9.9 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.4 136377.1_07624120_3 - 5.2e-05 23.7 0.1 0.18 12.4 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.4 136377.1_07624120_3 - 0.001 18.8 2.4 1.7 8.5 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4807 PF16065.3 136377.1_07624120_3 - 0.0049 16.4 0.4 0.53 9.8 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4807) Rapsyn_N PF10579.7 136377.1_07624120_3 - 0.021 14.8 0.2 0.59 10.1 0.0 3.0 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF4346 PF14251.4 136377.1_07624120_3 - 0.067 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) TPR_3 PF07720.10 136377.1_07624120_3 - 0.12 12.3 9.5 0.19 11.6 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.5 136377.1_07624120_3 - 2.7 8.1 7.9 2.4 8.3 0.8 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.4 136377.1_07624120_3 - 2.9 8.3 6.2 40 4.8 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.4 136377.1_07624120_3 - 3.3 8.1 22.9 9.9 6.5 0.1 6.7 6 1 1 7 7 7 0 Tetratricopeptide repeat Sprouty PF05210.11 071072.1_07621120_2 - 0.16 12.4 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 Sprouty protein (Spry) UvrD_C_2 PF13538.4 071131.1_07620120_1 - 0.088 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Nramp PF01566.16 132544.1_07623120_1 - 5.5e-78 262.3 6.3 6.9e-78 262.0 6.3 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Nramp PF01566.16 132544.1_07623120_2 - 6.1e-28 97.7 0.8 6.1e-28 97.7 0.8 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Globin PF00042.20 132546.1_07623120_1 - 0.0026 18.2 0.6 0.0044 17.4 0.0 1.6 2 0 0 2 2 2 1 Globin zf-C2H2_10 PF16588.3 071533.1_07621120_2 - 0.24 11.0 3.5 0.35 10.5 0.8 2.1 2 0 0 2 2 2 0 C2H2 zinc-finger DUF2735 PF10931.6 071549.2_07621120_1 - 0.058 14.0 0.0 0.089 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) Colicin_V PF02674.14 071549.2_07621120_2 - 0.052 13.4 0.1 0.052 13.4 0.1 1.1 1 0 0 1 1 1 0 Colicin V production protein RE_ScaI PF09569.8 102223.1_07621120_2 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 ScaI restriction endonuclease CAP PF00188.24 002412.1_07622120_1 - 0.00013 22.7 1.3 0.00024 21.8 0.1 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Tir_receptor_N PF07490.9 072492.1_07621120_2 - 0.14 11.9 0.2 0.15 11.7 0.2 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Gly_acyl_tr_C PF08444.8 002426.1_07622120_3 - 0.049 13.7 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region FR47 PF08445.8 002426.1_07622120_3 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein IP_trans PF02121.16 058478.3_07622001_1 - 5.4e-89 297.9 0.0 6.1e-89 297.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Aldo_ket_red PF00248.19 058904.6_07622001_1 - 5.9e-06 25.5 0.1 8.5e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family TBCC_N PF16752.3 058904.6_07622001_1 - 0.076 13.3 0.1 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain CCD48 PF15799.3 058904.6_07622001_1 - 0.19 10.0 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF896 PF05979.10 059828.4_07622001_1 - 0.0097 15.6 0.2 0.037 13.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF896) Costars PF14705.4 001136300.2_07621001_1 - 4.2e-32 110.0 0.4 8.8e-32 109.0 0.3 1.6 2 0 0 2 2 2 1 Costars AF-4 PF05110.11 001136300.2_07621001_2 - 0.032 12.2 0.0 0.036 12.0 0.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein cNMP_binding PF00027.27 060026.5_07625001_1 - 1.4e-18 66.6 0.0 2.5e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RPEL PF02755.13 060077.3_07624001_1 - 7.1e-14 50.9 10.8 9.8e-08 31.3 4.1 2.4 2 0 0 2 2 2 2 RPEL repeat BAR PF03114.16 060224.5_07622001_1 - 8.6e-07 28.7 3.3 1.1e-06 28.4 3.3 1.1 1 0 0 1 1 1 1 BAR domain HMMR_C PF15908.3 060224.5_07622001_1 - 0.0095 16.1 2.3 0.014 15.5 1.7 1.6 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal BAR_3 PF16746.3 060224.5_07622001_1 - 0.11 12.1 4.9 0.16 11.5 4.9 1.3 1 1 0 1 1 1 0 BAR domain of APPL family Ly49 PF08391.8 060224.5_07622001_1 - 0.11 12.7 1.2 0.24 11.6 1.1 1.7 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region TMPIT PF07851.11 060224.5_07622001_1 - 0.12 11.5 1.2 0.19 10.8 1.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein THOC7 PF05615.11 060224.5_07622001_1 - 0.16 12.2 2.1 0.32 11.1 2.1 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 DUF16 PF01519.14 060224.5_07622001_1 - 0.18 12.2 3.8 4.5 7.7 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1043 PF06295.10 060224.5_07622001_1 - 0.32 10.8 3.4 3.4 7.5 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Syntaxin_2 PF14523.4 060224.5_07622001_1 - 1.5 9.1 5.8 8.9 6.6 5.5 2.7 2 1 0 2 2 2 0 Syntaxin-like protein DPM3 PF08285.9 060224.5_07622001_1 - 2.5 8.2 3.9 10 6.2 0.2 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Ank_2 PF12796.5 001265157.1_07626001_1 - 1.6e-60 201.5 22.7 4.6e-07 30.2 0.0 11.3 2 2 8 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001265157.1_07626001_1 - 3.4e-56 186.8 16.3 3.6e-06 27.3 0.0 13.3 10 4 4 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.4 001265157.1_07626001_1 - 8.7e-42 136.2 19.9 0.037 14.4 0.1 19.3 21 0 0 21 21 21 9 Ankyrin repeat Ank_5 PF13857.4 001265157.1_07626001_1 - 2.5e-41 138.9 21.7 0.00016 21.8 0.3 13.5 7 3 9 16 16 16 13 Ankyrin repeats (many copies) Ank PF00023.28 001265157.1_07626001_1 - 1.1e-27 95.1 17.5 0.0098 16.2 0.0 16.3 17 0 0 17 17 17 7 Ankyrin repeat FYVE PF01363.19 001265157.1_07626001_1 - 8.9e-15 54.5 11.6 2.8e-14 52.9 11.6 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.14 001265157.1_07626001_1 - 0.07 13.2 9.2 0.021 14.9 5.1 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger DMAP1 PF05499.10 001129058.2_07623001_1 - 1.1e-56 191.1 5.3 1.3e-56 190.9 3.7 1.9 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.3 001129058.2_07623001_1 - 3.6e-30 103.8 4.4 8.9e-30 102.6 4.4 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Mucin PF01456.15 001129058.2_07623001_1 - 6.2 6.7 15.8 0.24 11.2 6.6 2.6 3 0 0 3 3 3 0 Mucin-like glycoprotein FBA_2 PF07735.15 001316863.1_07623001_1 - 7e-10 38.8 3.1 7e-10 38.8 3.1 2.3 2 0 0 2 2 2 1 F-box associated DUF4636 PF15468.4 061999.5_07623001_1 - 0.12 11.9 2.4 0.23 11.0 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) GxGYxYP_N PF16216.3 001026789.4_07623001_1 - 0.067 13.2 1.0 2.3 8.2 0.0 2.9 2 1 0 2 2 2 0 GxGYxY sequence motif in domain of unknown function N-terminal DUF3038 PF11237.6 001026789.4_07623001_1 - 0.18 11.7 8.2 4.9 7.0 2.8 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3038) Mut7-C PF01927.14 001026789.4_07623001_1 - 1.8 8.5 12.6 0.2 11.6 4.6 3.1 2 1 1 3 3 3 0 Mut7-C RNAse domain DUF948 PF06103.9 001026789.4_07623001_1 - 2.1 8.5 7.6 1.3 9.2 0.2 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Ribosomal_L17 PF01196.17 001026789.4_07623001_1 - 2.3 9.1 5.5 2.2 9.1 2.1 2.7 2 1 0 2 2 2 0 Ribosomal protein L17 FlaC_arch PF05377.9 001026789.4_07623001_1 - 6.8 7.0 8.6 8.5 6.7 0.4 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DB PF01682.17 001267184.1_07624001_1 - 1.8e-19 69.8 12.0 4.3e-19 68.5 12.0 1.7 1 0 0 1 1 1 1 DB module DOMON PF03351.15 063003.4_07622001_1 - 9.1e-06 25.8 0.2 1.8e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 DOMON domain Pkinase_Tyr PF07714.15 063018.4_07625001_1 - 5.6e-58 196.1 0.0 9.7e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 063018.4_07625001_1 - 1.5e-28 99.8 0.0 4.2e-28 98.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain DUF4448 PF14610.4 001026778.1_07625001_1 - 0.087 12.5 0.6 3.6 7.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) ABA_GPCR PF12430.6 001026778.1_07625001_3 - 0.073 12.7 2.1 0.12 12.0 2.1 1.2 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor FHA PF00498.24 063973.2_07623001_1 - 3.7e-10 39.9 0.0 9.2e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.3 063973.2_07623001_1 - 0.0023 18.1 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APC_u5 PF16630.3 063973.2_07623001_1 - 0.067 14.1 0.1 0.18 12.7 0.1 1.6 1 0 0 1 1 1 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs DdrB PF12747.5 001267353.1_07623001_1 - 0.83 9.3 11.9 29 4.3 0.2 5.0 1 1 5 6 6 6 0 DdrB-like protein Lipase_GDSL PF00657.20 064039.5_07623001_1 - 7.6e-10 39.0 0.0 1.6e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.4 064039.5_07623001_1 - 0.00018 21.9 0.1 0.003 17.8 0.0 2.5 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF2192 PF09958.7 064204.3_07623001_1 - 0.029 13.8 0.1 0.054 12.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) LUC7 PF03194.13 064204.3_07623001_1 - 0.27 10.7 1.8 0.27 10.7 0.1 1.9 2 1 0 2 2 2 0 LUC7 N_terminus BCD PF15461.4 182168.1_07622001_2 - 0.088 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase DUF3482 PF11981.6 001267462.1_07621001_1 - 0.084 12.1 1.2 0.097 11.9 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Iwr1 PF08574.8 064542.5_07622001_1 - 1.6e-09 38.5 15.6 1.6e-09 38.5 15.6 2.5 2 1 0 2 2 2 1 Transcription factor Iwr1 Autoind_bind PF03472.13 064542.5_07622001_2 - 0.016 14.5 0.1 0.036 13.4 0.1 1.5 1 0 0 1 1 1 0 Autoinducer binding domain ALG3 PF05208.11 001267489.1_07624001_1 - 1.1e-129 432.8 28.2 1.5e-129 432.4 28.2 1.1 1 0 0 1 1 1 1 ALG3 protein Laminin_G_2 PF02210.22 001267509.1_07626001_1 - 1.4e-56 190.4 2.0 6.5e-29 100.9 0.3 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.21 001267509.1_07626001_1 - 2.9e-50 169.7 0.9 1.9e-28 99.2 0.1 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.4 001267509.1_07626001_1 - 2.1e-08 34.3 0.5 0.003 17.6 0.2 2.9 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.25 001267509.1_07626001_1 - 2.2e-06 27.7 38.0 0.0022 18.2 3.9 3.7 4 0 0 4 4 4 3 EGF-like domain DUF1080 PF06439.9 001267509.1_07626001_1 - 0.036 14.0 0.3 0.35 10.8 0.1 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1080) MPS2 PF17060.3 001027296.3_07624001_1 - 0.00097 18.4 5.4 0.0016 17.7 5.4 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 CTNNB1_binding PF08347.9 001027296.3_07624001_1 - 0.044 13.8 1.9 0.085 12.9 1.9 1.5 1 0 0 1 1 1 0 N-terminal CTNNB1 binding AAA_23 PF13476.4 064750.3_07621001_1 - 0.074 13.4 9.7 0.085 13.2 9.7 1.0 1 0 0 1 1 1 0 AAA domain UNC45-central PF11701.6 064804.5_07626001_1 - 3.6e-26 91.8 1.7 1.4e-25 89.9 0.0 3.0 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central TPR_2 PF07719.15 064804.5_07626001_1 - 1.4e-10 40.3 0.6 0.054 13.5 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.26 064804.5_07626001_1 - 2.7e-06 26.8 0.8 0.053 13.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.4 064804.5_07626001_1 - 0.0019 18.1 1.5 2.1 8.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.4 064804.5_07626001_1 - 0.0025 17.8 1.4 1.2 9.2 0.2 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat HEAT_2 PF13646.4 064804.5_07626001_1 - 0.022 15.0 6.5 40 4.5 0.0 6.6 8 3 1 9 9 9 0 HEAT repeats TPR_12 PF13424.4 064804.5_07626001_1 - 0.028 14.6 4.5 0.037 14.2 0.6 3.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.4 064804.5_07626001_1 - 0.28 11.2 4.7 0.24 11.4 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.4 064804.5_07626001_1 - 0.61 10.7 5.1 0.26 11.9 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.4 064804.5_07626001_1 - 0.85 10.5 3.5 5.6 7.9 0.0 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat FtsJ PF01728.17 065255.4_07625001_1 - 7.4e-58 195.4 0.1 1.4e-57 194.5 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.6 065255.4_07625001_1 - 3.5e-36 124.3 14.1 3.5e-36 124.3 14.1 4.7 2 1 3 5 5 5 1 Domain of unknown function (DUF3381) Spb1_C PF07780.10 065255.4_07625001_1 - 7.6e-34 117.1 17.7 7.6e-34 117.1 17.7 3.8 2 1 1 3 3 3 1 Spb1 C-terminal domain YlqD PF11068.6 065255.4_07625001_1 - 6.4 7.0 14.7 0.61 10.3 8.9 2.3 2 0 0 2 2 2 0 YlqD protein MotB_plug PF13677.4 001027448.3_07625001_1 - 0.37 10.3 2.0 1.2 8.7 2.0 1.9 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Pox_D5 PF03288.14 001312940.1_07623001_1 - 1 9.8 8.0 7.5 7.0 0.1 3.3 3 1 0 3 3 3 0 Poxvirus D5 protein-like Cyclin_N PF00134.21 181947.4_07622001_1 - 4.2e-12 45.8 0.0 6.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.30 065804.7_07623001_1 - 2.1e-35 120.0 17.5 2.1e-07 31.4 0.6 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 065804.7_07623001_1 - 2e-06 27.9 2.4 3.7 7.8 0.1 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 065804.7_07623001_1 - 4.6e-05 22.1 6.7 0.00099 17.7 0.0 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.9 065804.7_07623001_1 - 0.01 14.5 0.2 0.22 10.1 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Motile_Sperm PF00635.24 001356772.1_07622001_1 - 4e-16 58.7 0.0 7.4e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PRIMA1 PF16101.3 001356772.1_07622001_1 - 0.073 13.0 1.3 0.18 11.7 1.3 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1754 PF08555.8 066209.4_07622001_1 - 3.2 8.5 5.2 0.97 10.1 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) RPAP1_N PF08621.8 001028061.3_07624001_1 - 8.8e-14 50.9 2.5 1.1e-13 50.6 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal DUF3835 PF12927.5 001028061.3_07624001_1 - 3.9 8.3 9.3 0.11 13.3 0.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3835) CpXC PF14353.4 171269.4_07623001_1 - 6.1e-05 22.9 5.8 0.0054 16.6 0.4 2.5 2 0 0 2 2 2 2 CpXC protein zf-C2HE PF16278.3 171269.4_07623001_1 - 0.0024 18.2 3.0 0.016 15.5 0.2 2.7 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.4 171269.4_07623001_1 - 0.012 15.4 0.9 0.037 13.8 0.9 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.4 171269.4_07623001_1 - 0.018 15.7 15.0 0.2 12.4 2.8 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger XPA_N PF01286.16 171269.4_07623001_1 - 1.1 9.2 4.4 0.32 11.0 0.4 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2 PF00096.24 171269.4_07623001_1 - 6.9 7.2 13.2 11 6.5 0.1 3.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type IBR PF01485.19 171269.4_07623001_1 - 9 6.5 9.5 16 5.7 3.9 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain SAPS PF04499.13 001028329.2_07624001_1 - 3 6.4 6.2 3.9 6.0 6.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_M24 PF00557.22 067910.6_07623001_1 - 7.5e-25 87.7 0.1 9.4e-25 87.4 0.1 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 RNase_P_Rpp14 PF01900.17 001347301.1_07621001_1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 Rpp14/Pop5 family ZU5 PF00791.18 001306822.1_07625001_1 - 1e-22 80.2 0.0 2.3e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Death PF00531.20 001306822.1_07625001_1 - 4.4e-13 49.1 0.0 7.3e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Death domain UPA PF17217.1 001306822.1_07625001_1 - 1.8e-10 40.9 0.0 3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 UPA domain TSP_1 PF00090.17 001306822.1_07625001_1 - 3.3e-06 27.1 8.2 3.3e-06 27.1 8.2 4.2 4 0 0 4 4 4 2 Thrombospondin type 1 domain Ig_2 PF13895.4 001306822.1_07625001_1 - 0.014 15.6 0.1 0.035 14.3 0.1 1.8 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.14 001306822.1_07625001_1 - 0.024 14.5 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain PMP22_Claudin PF00822.18 001306822.1_07625001_1 - 0.031 14.0 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Ig_3 PF13927.4 001306822.1_07625001_1 - 0.078 13.5 0.6 0.18 12.3 0.1 2.0 2 0 0 2 2 2 0 Immunoglobulin domain Ion_trans PF00520.29 001306892.1_07629001_1 - 1.9e-117 390.7 115.3 1.7e-33 115.7 19.2 4.1 4 0 0 4 4 4 4 Ion transport protein DUF272 PF03312.13 068531.3_07623001_1 - 1.2e-41 141.7 0.8 2.5e-41 140.6 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF272) Benyvirus_P25 PF05744.9 068531.3_07623001_1 - 0.0073 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Benyvirus P25/P26 protein GDPD PF03009.15 068775.3_07623001_1 - 8.5e-60 202.5 0.1 1.1e-59 202.2 0.1 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PGPGW PF09656.8 068775.3_07623001_1 - 0.00062 19.1 1.7 0.001 18.4 1.7 1.3 1 0 0 1 1 1 1 Putative transmembrane protein (PGPGW) DUF433 PF04255.12 068775.3_07623001_1 - 0.047 13.4 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF433) PDZ_2 PF13180.4 069158.2_07629001_1 - 7.5e-05 22.8 0.2 0.00025 21.2 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.22 069158.2_07629001_1 - 8.6e-05 22.7 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) C1_1 PF00130.20 069158.2_07629001_1 - 0.00033 20.3 5.4 0.00074 19.2 5.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TGF_beta PF00019.18 069165.5_07623001_1 - 4.2e-21 75.7 1.1 1.1e-20 74.3 1.1 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain Cys_knot PF00007.20 069165.5_07623001_1 - 0.089 13.0 0.8 0.2 11.8 0.8 1.6 1 0 0 1 1 1 0 Cystine-knot domain DAN PF03045.13 069165.5_07623001_1 - 0.24 11.3 5.2 0.04 13.8 1.1 1.8 2 0 0 2 2 2 0 DAN domain DUF2202 PF09968.7 069596.5_07623001_1 - 0.008 15.9 0.5 0.035 13.8 0.2 2.3 2 1 0 2 2 2 1 Uncharacterized protein domain (DUF2202) SAC3_GANP PF03399.14 171422.3_07622001_1 - 5.1e-47 160.5 0.3 6.4e-47 160.2 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP family PCI PF01399.25 171422.3_07622001_1 - 0.16 12.4 0.6 0.82 10.1 0.0 2.3 2 1 0 2 2 2 0 PCI domain FXa_inhibition PF14670.4 001307151.1_07629001_1 - 1.6e-60 200.9 154.4 6.3e-12 45.4 11.8 39.0 14 4 14 28 28 28 9 Coagulation Factor Xa inhibitory site cEGF PF12662.5 001307151.1_07629001_1 - 2.2e-29 100.9 51.1 4.7e-08 32.7 3.0 42.8 43 5 4 47 47 47 10 Complement Clr-like EGF-like Laminin_EGF PF00053.22 001307151.1_07629001_1 - 1.9e-27 95.0 640.8 0.0015 18.5 16.0 35.0 8 7 26 34 34 34 20 Laminin EGF domain EGF_CA PF07645.13 001307151.1_07629001_1 - 7.8e-18 64.3 93.0 1.4e-06 28.3 10.7 35.5 29 5 5 34 34 34 7 Calcium-binding EGF domain hEGF PF12661.5 001307151.1_07629001_1 - 6.2e-08 32.9 488.6 0.0011 19.4 6.3 41.8 39 4 2 41 41 41 20 Human growth factor-like EGF EGF PF00008.25 001307151.1_07629001_1 - 3.5e-06 27.1 37.1 0.0005 20.2 8.1 40.8 42 2 1 43 43 43 20 EGF-like domain EGF_2 PF07974.11 001307151.1_07629001_1 - 1.1e-05 25.5 67.9 0.00043 20.5 12.2 49.6 37 17 8 46 46 46 16 EGF-like domain EGF_3 PF12947.5 001307151.1_07629001_1 - 0.00059 19.8 3.8 0.00059 19.8 3.8 35.7 32 4 2 34 34 34 9 EGF domain zf-U11-48K PF05253.10 070599.1_07622001_1 - 4.4e-14 51.9 6.1 6.4e-07 29.0 1.2 2.4 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger UNC-93 PF05978.14 001029061.1_07623001_1 - 2.9e-59 199.2 12.6 2.9e-59 199.2 12.6 3.2 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.14 001029061.1_07623001_1 - 8.4e-08 31.4 46.6 3.4e-05 22.8 16.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PRiA4_ORF3 PF07929.9 071162.3_07623001_1 - 0.092 12.3 0.6 0.3 10.6 0.3 1.9 2 0 0 2 2 2 0 Plasmid pRiA4b ORF-3-like protein GIT1_C PF12205.6 071162.3_07623001_1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term WBP-1 PF11669.6 071162.3_07623001_1 - 0.46 11.0 2.2 0.96 10.0 0.6 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 FBA_2 PF07735.15 072033.6_07623001_1 - 6.7e-11 42.0 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 F-box associated F-box PF00646.31 072033.6_07623001_1 - 0.04 13.7 0.4 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 F-box domain HTH_3 PF01381.20 072033.6_07623001_3 - 0.018 14.9 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Ion_trans PF00520.29 001028621.3_07624001_1 - 2.6e-38 131.5 8.6 2.6e-38 131.5 8.6 1.4 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.20 001028621.3_07624001_1 - 5e-22 77.9 0.0 1.3e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001028621.3_07624001_1 - 4.7e-14 52.0 8.6 1.3e-13 50.6 8.6 1.8 1 0 0 1 1 1 1 Ion channel BTB_3 PF16017.3 001028621.3_07624001_1 - 0.0047 16.9 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain DUF423 PF04241.13 001028621.3_07624001_1 - 0.041 14.0 0.1 0.14 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF423) DUF3855 PF12967.5 001028621.3_07624001_1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) PKD_channel PF08016.10 001028621.3_07624001_1 - 0.81 8.2 10.2 0.039 12.5 4.0 1.8 2 0 0 2 2 2 0 Polycystin cation channel DUF3573 PF12097.6 072823.3_07622001_2 - 7.8 5.1 6.7 11 4.6 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TPR_7 PF13176.4 072911.4_07628001_1 - 6.1e-07 28.9 2.8 0.17 11.8 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.15 072911.4_07628001_1 - 3.2e-06 26.7 10.6 0.07 13.1 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.26 072911.4_07628001_1 - 2e-05 24.1 7.5 0.0055 16.3 0.1 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.4 072911.4_07628001_1 - 6e-05 23.4 2.2 1.3 9.9 0.0 6.0 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.4 072911.4_07628001_1 - 0.0017 18.3 0.1 0.61 10.3 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.4 072911.4_07628001_1 - 0.0022 18.1 9.6 0.057 13.6 0.3 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.4 072911.4_07628001_1 - 0.0054 16.3 0.1 6.7 6.4 0.1 3.6 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.4 072911.4_07628001_1 - 0.006 16.8 0.6 0.11 12.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Inhibitor_I34 PF10466.7 072911.4_07628001_1 - 0.0063 17.0 1.9 0.019 15.4 1.9 1.8 1 0 0 1 1 1 1 Saccharopepsin inhibitor I34 Gamma_PGA_hydro PF05908.9 072911.4_07628001_1 - 0.046 13.0 0.5 0.49 9.6 0.5 2.2 1 1 0 1 1 1 0 Poly-gamma-glutamate hydrolase TPR_19 PF14559.4 072911.4_07628001_1 - 0.11 12.9 4.5 1.8 9.0 0.0 4.1 4 1 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.4 072911.4_07628001_1 - 0.12 12.9 1.1 0.95 10.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4192 PF13830.4 072911.4_07628001_1 - 0.46 10.3 3.2 0.85 9.4 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) TPR_10 PF13374.4 072911.4_07628001_1 - 2.2 8.2 4.6 2 8.2 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat G-patch PF01585.21 001330874.1_07624001_1 - 4.1e-17 61.7 3.2 8e-17 60.8 3.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.5 001330874.1_07624001_1 - 0.00011 22.0 0.4 0.00035 20.5 0.4 1.9 1 0 0 1 1 1 1 G-patch domain Smg4_UPF3 PF03467.13 001330874.1_07624001_1 - 0.023 14.6 0.1 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 Smg-4/UPF3 family BRAP2 PF07576.10 001330874.1_07624001_1 - 0.025 14.7 0.3 0.28 11.3 0.3 2.2 1 1 0 1 1 1 0 BRCA1-associated protein 2 RRM_1 PF00076.20 001330874.1_07624001_1 - 0.028 14.1 0.1 4 7.2 0.0 3.4 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.22 001129449.2_07624001_1 - 9.6e-33 113.6 24.6 1.5e-32 113.0 24.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001129449.2_07624001_1 - 1.4e-12 47.1 17.1 1.4e-12 47.1 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2157 PF09925.7 001129449.2_07624001_1 - 0.61 9.7 11.8 0.26 11.0 0.4 3.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) DAN PF03045.13 001269413.1_07621001_1 - 1.9e-28 98.6 8.1 2.1e-28 98.5 8.1 1.0 1 0 0 1 1 1 1 DAN domain DUF2318 PF10080.7 001269413.1_07621001_1 - 0.067 13.2 2.8 0.088 12.8 2.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) Peptidase_C13 PF01650.16 073736.5_07623001_1 - 9.5e-104 346.3 0.5 1.6e-103 345.6 0.1 1.5 2 0 0 2 2 2 1 Peptidase C13 family Lipoprotein_19 PF13617.4 073736.5_07623001_1 - 0.054 13.2 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 YnbE-like lipoprotein MREG PF15812.3 073736.5_07623001_1 - 0.088 13.0 0.6 0.17 12.1 0.6 1.4 1 0 0 1 1 1 0 Melanoregulin DUF3287 PF11690.6 073736.5_07623001_1 - 0.15 11.6 1.0 0.32 10.6 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) FYVE PF01363.19 073780.6_07623001_1 - 8.5e-08 32.1 8.4 1.9e-07 31.0 8.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger UPF0184 PF03670.11 073780.6_07623001_1 - 0.0023 18.1 5.0 0.0023 18.1 5.0 2.2 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0184) zf-4CXXC_R1 PF10497.7 073780.6_07623001_1 - 0.061 13.5 5.8 0.18 12.0 5.8 1.8 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF2318 PF10080.7 073780.6_07623001_1 - 1.8 8.6 5.6 5.5 7.0 5.6 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) Aldo_ket_red PF00248.19 073921.5_07622001_1 - 4.9e-45 153.8 0.1 2.6e-43 148.1 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Tagatose_6_P_K PF08013.9 073921.5_07622001_1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Paf67 PF10255.7 073921.5_07622001_1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 CUB_2 PF02408.18 001028711.3_07623001_1 - 9.8e-06 25.2 2.6 1.1e-05 25.0 0.3 2.3 2 0 0 2 2 2 1 CUB-like domain DUF19 PF01579.16 074095.7_07622001_1 - 6.8e-20 71.3 29.0 9e-20 70.9 29.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF19) FadA PF09403.8 074095.7_07622001_1 - 0.007 16.7 2.1 0.016 15.5 1.8 1.8 1 1 0 1 1 1 1 Adhesion protein FadA IncA PF04156.12 074095.7_07622001_1 - 0.1 12.3 5.5 0.4 10.3 5.5 1.9 1 1 0 1 1 1 0 IncA protein FANCI_HD1 PF14679.4 074095.7_07622001_1 - 0.12 12.2 5.0 3.5 7.5 0.4 2.8 2 2 0 2 2 2 0 FANCI helical domain 1 Seryl_tRNA_N PF02403.20 074095.7_07622001_1 - 0.74 9.9 7.8 5.2 7.2 0.5 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LEAP-2 PF07359.9 074095.7_07622001_1 - 1.6 8.5 8.7 9.8 6.0 4.7 2.7 2 1 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) V-ATPase_G PF03179.13 074095.7_07622001_1 - 2.4 8.6 7.9 0.68 10.4 1.6 2.4 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DZF PF07528.12 074213.5_07623001_1 - 2.9e-108 361.1 0.0 4.6e-108 360.4 0.0 1.3 1 0 0 1 1 1 1 DZF domain zf-RING_2 PF13639.4 074286.5_07622001_1 - 7.7e-07 29.1 5.9 1.6e-06 28.1 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.4 074286.5_07622001_1 - 2.1e-06 27.5 6.3 4e-06 26.6 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.23 074286.5_07622001_1 - 4.5e-05 23.1 6.7 9.1e-05 22.1 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 074286.5_07622001_1 - 7.9e-05 22.5 6.2 0.00016 21.5 6.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.4 074286.5_07622001_1 - 0.0056 16.4 4.4 0.018 14.8 4.2 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.3 074286.5_07622001_1 - 0.0092 15.6 0.2 0.0092 15.6 0.2 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 074286.5_07622001_1 - 0.011 15.4 7.0 0.022 14.5 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.4 074286.5_07622001_1 - 0.043 13.4 7.7 0.1 12.2 7.1 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.4 074286.5_07622001_1 - 0.063 13.3 7.5 0.2 11.7 7.3 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.5 074286.5_07622001_1 - 0.11 12.7 4.6 0.21 11.7 4.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.9 074286.5_07622001_1 - 0.32 10.8 6.9 0.6 9.9 6.8 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) PRKG1_interact PF15898.3 074286.5_07622001_1 - 0.33 11.8 16.7 0.054 14.3 9.0 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FYVE PF01363.19 074286.5_07622001_1 - 0.65 10.0 5.5 1.3 9.1 5.5 1.6 1 0 0 1 1 1 0 FYVE zinc finger Exonuc_VII_L PF02601.13 074286.5_07622001_1 - 0.68 9.3 7.4 0.84 9.0 7.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.10 074286.5_07622001_1 - 2.2 7.4 10.9 2.8 7.1 10.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 NBP1 PF08537.8 074286.5_07622001_1 - 2.5 7.3 14.3 2.3 7.4 12.0 1.8 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 DUF342 PF03961.11 074286.5_07622001_1 - 2.5 6.5 8.2 2.9 6.2 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CLZ PF16526.3 074286.5_07622001_1 - 2.8 8.2 12.7 1.5 9.1 3.2 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.7 074286.5_07622001_1 - 8.6 6.5 9.3 8.5 6.5 2.2 3.3 3 1 1 4 4 4 0 Haemolysin XhlA TIL PF01826.15 001276999.1_07624001_1 - 3.5e-34 116.7 134.0 2.7e-11 43.4 18.5 9.0 7 2 1 8 8 8 5 Trypsin Inhibitor like cysteine rich domain TMF_TATA_bd PF12325.6 075763.4_07623001_1 - 0.00025 21.1 31.5 0.0025 17.9 11.7 3.7 1 1 3 4 4 4 2 TATA element modulatory factor 1 TATA binding Cluap1 PF10234.7 075763.4_07623001_1 - 0.3 10.3 24.0 1.7 7.9 10.7 3.2 1 1 2 3 3 3 0 Clusterin-associated protein-1 DUF1664 PF07889.10 075763.4_07623001_1 - 0.67 9.8 14.9 0.5 10.2 2.7 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.7 075763.4_07623001_1 - 0.76 9.0 35.6 0.011 15.2 15.5 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 BTB_2 PF02214.20 075982.5_07621001_1 - 3.9e-11 43.0 0.0 7.5e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RRM_1 PF00076.20 171681.4_07623001_1 - 1.2e-25 89.0 0.0 4.9e-17 61.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 171681.4_07623001_1 - 0.00023 21.1 0.0 0.0025 17.8 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.4 171681.4_07623001_1 - 0.012 15.1 0.0 0.032 13.7 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.9 171681.4_07623001_1 - 0.012 15.1 0.5 2.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Ribonuclease B OB domain SET_assoc PF11767.6 171681.4_07623001_1 - 0.16 11.5 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Band_7 PF01145.23 001029396.2_07622001_1 - 5.7e-32 111.0 2.0 8.1e-32 110.5 2.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.4 001029396.2_07622001_1 - 0.00066 19.3 0.2 0.00098 18.7 0.2 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family Clathrin_H_link PF13838.4 001029396.2_07622001_1 - 0.096 12.5 0.9 0.86 9.4 0.2 2.3 2 0 0 2 2 2 0 Clathrin-H-link zf-RanBP PF00641.16 076566.3_07623001_1 - 8.5e-07 28.0 2.0 1.8e-06 27.0 2.0 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF973 PF06157.9 171695.1_07622001_1 - 0.044 12.7 0.1 0.054 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Myb_DNA-bind_3 PF12776.5 001136449.1_07622001_1 - 0.04 14.6 1.7 0.098 13.4 0.6 2.0 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DSL PF01414.17 001129658.2_07623001_1 - 0.00067 19.6 1.4 0.0011 18.9 0.3 2.0 1 1 0 1 1 1 1 Delta serrate ligand zf-C2H2 PF00096.24 076812.4_07623001_1 - 4e-14 52.0 27.1 0.00019 21.6 1.1 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 076812.4_07623001_1 - 1.7e-07 31.3 26.9 0.002 18.6 1.3 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.4 076812.4_07623001_1 - 7.6e-06 26.0 25.1 0.00039 20.6 0.4 5.6 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.6 076812.4_07623001_1 - 0.00087 19.4 3.9 0.072 13.3 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding DZR PF12773.5 076812.4_07623001_1 - 0.00097 19.0 5.3 0.41 10.6 0.2 3.4 3 0 0 3 3 3 2 Double zinc ribbon zf-Di19 PF05605.10 076812.4_07623001_1 - 0.053 13.7 15.9 0.3 11.3 0.5 3.6 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.8 076812.4_07623001_1 - 0.37 10.8 10.8 1.1 9.3 0.9 3.7 3 1 0 3 3 3 0 Zinc ribbon domain DUF2256 PF10013.7 076812.4_07623001_1 - 0.65 10.0 3.9 12 6.0 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-trcl PF13451.4 076812.4_07623001_1 - 0.75 9.6 9.2 2.1 8.2 0.1 4.0 4 0 0 4 4 4 0 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.3 076812.4_07623001_1 - 0.82 10.3 7.5 15 6.3 2.4 3.2 2 1 1 3 3 3 0 zinc-ribbon family zf-C2H2_2 PF12756.5 076812.4_07623001_1 - 1.4 9.2 12.8 7.1 6.9 0.2 4.0 2 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_10 PF10058.7 076812.4_07623001_1 - 1.6 8.4 4.7 3.2 7.4 0.2 3.2 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF3505 PF12013.6 076812.4_07623001_1 - 4.3 7.7 9.0 28 5.0 0.1 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3505) FYVE PF01363.19 076812.4_07623001_1 - 5.4 7.1 11.0 53 3.9 0.1 3.3 2 1 0 2 2 2 0 FYVE zinc finger zf-RING_7 PF02591.13 076812.4_07623001_1 - 6.1 7.0 6.7 4 7.6 0.1 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain JAKMIP_CC3 PF16034.3 001083285.2_07623001_1 - 0.0001 22.2 4.0 0.0001 22.2 4.0 3.9 1 1 3 4 4 4 1 JAKMIP CC3 domain Lebercilin PF15619.4 001083285.2_07623001_1 - 0.013 15.0 18.5 0.013 15.0 18.5 4.1 1 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.19 001083285.2_07623001_1 - 0.051 13.0 53.7 0.31 10.4 15.9 4.4 1 1 3 4 4 4 0 Intermediate filament protein FTR1 PF03239.12 001083285.2_07623001_1 - 0.31 10.0 2.9 0.77 8.7 2.9 1.6 1 0 0 1 1 1 0 Iron permease FTR1 family IncA PF04156.12 001083285.2_07623001_1 - 9.3 5.9 65.5 1.8 8.2 18.7 4.3 1 1 3 4 4 4 0 IncA protein SlyX PF04102.10 001083285.2_07623001_1 - 9.9 6.7 39.7 0.98 10.0 4.2 5.8 2 1 2 4 4 4 0 SlyX Kunitz_BPTI PF00014.21 077467.4_07627001_1 - 5.1e-124 404.3 86.7 2.1e-16 59.8 1.5 9.3 9 0 0 9 9 9 8 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.4 077467.4_07627001_1 - 5.7e-67 221.7 129.2 1.5e-10 41.2 13.0 9.6 8 1 0 8 8 8 8 Lustrin, cysteine-rich repeated domain SWIRM PF04433.15 077467.4_07627001_1 - 0.86 9.9 3.0 45 4.3 0.0 4.1 4 0 0 4 4 4 0 SWIRM domain Rad60-SLD_2 PF13881.4 078014.4_07623001_1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2213 PF09979.7 078014.4_07623001_1 - 0.29 11.0 1.1 2.3 8.1 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2213) DMAP1 PF05499.10 078014.4_07623001_1 - 1.9 8.2 7.1 0.13 12.0 0.5 2.3 2 1 1 3 3 3 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF1002 PF06207.9 078048.5_07622001_1 - 0.015 14.7 5.6 0.02 14.3 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF1049 PF06305.9 078048.5_07622001_1 - 0.1 12.3 0.1 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF4407 PF14362.4 078048.5_07622001_1 - 0.11 11.7 2.9 0.15 11.2 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.20 078048.5_07622001_1 - 0.19 10.8 3.3 0.26 10.3 3.2 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.3 078048.5_07622001_1 - 1.9 5.4 14.9 2.2 5.1 14.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CENP-B_dimeris PF09026.8 078048.5_07622001_1 - 2.2 8.6 10.1 6.7 7.0 10.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ets PF00178.20 001270332.1_07623001_1 - 2.8e-29 101.3 0.0 5.9e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.14 001270332.1_07623001_1 - 2.9e-07 30.2 0.0 1.1e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain TSC22 PF01166.16 001307889.1_07621001_1 - 9.1e-26 89.8 0.7 1.2e-25 89.4 0.7 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family SOGA PF11365.6 001307889.1_07621001_1 - 0.049 14.6 0.2 0.074 14.1 0.2 1.3 1 0 0 1 1 1 0 Protein SOGA Fib_alpha PF08702.8 063017.1_07622001_1 - 0.42 10.7 5.8 0.82 9.7 5.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family 2OG-FeII_Oxy_2 PF13532.4 070121.2_07622001_1 - 1.6e-11 44.7 0.0 6.9e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.18 070121.2_07622001_1 - 0.0077 16.6 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-FLZ PF04570.12 001029156.2_07622001_1 - 0.14 11.6 2.1 0.26 10.7 2.1 1.4 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Pkinase PF00069.23 069692.1_07623001_1 - 6e-21 74.8 0.0 6e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 069692.1_07623001_1 - 1.7e-09 37.2 0.0 1.7e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.21 069692.1_07623001_1 - 0.013 15.3 0.0 0.5 10.1 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DDHD PF02862.15 069692.1_07623001_1 - 0.18 11.8 3.0 0.24 11.4 3.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF4110 PF13422.4 069692.1_07623001_1 - 2.3 8.2 17.7 3.6 7.6 16.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Osteopontin PF00865.16 075148.1_07622001_1 - 0.011 15.1 4.1 0.016 14.6 4.1 1.2 1 0 0 1 1 1 0 Osteopontin Moulting_cycle PF04870.14 075148.1_07622001_1 - 0.071 12.3 8.4 0.086 12.0 8.0 1.3 1 1 0 1 1 1 0 Moulting cycle Metalloenzyme PF01676.16 075148.1_07622001_1 - 0.12 11.6 0.2 0.16 11.2 0.2 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily FTA4 PF13093.4 075148.1_07622001_1 - 0.57 9.9 5.4 0.71 9.6 5.4 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GlutR_dimer PF00745.18 075148.1_07622001_1 - 0.94 9.8 5.3 1.3 9.4 2.6 2.1 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain zf-CpG_bind_C PF12269.6 075148.1_07622001_1 - 0.98 9.0 5.5 0.96 9.0 4.1 1.6 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Glyco_transf_92 PF01697.25 070842.3_07623001_1 - 3.8e-69 233.1 6.2 5.2e-69 232.7 6.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.4 070842.3_07623001_1 - 0.0023 18.3 3.1 0.007 16.7 3.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 TPR_MLP1_2 PF07926.10 062342.3_07623001_1 - 0.0042 17.0 40.1 0.14 12.1 9.7 2.9 2 1 0 2 2 2 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.10 062342.3_07623001_1 - 0.051 12.8 4.7 0.082 12.2 4.7 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Golgin_A5 PF09787.7 062342.3_07623001_1 - 1.4 8.2 41.5 3.5 6.9 41.5 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 Thioredoxin_3 PF13192.4 062342.3_07623001_1 - 1.6 8.7 4.9 42 4.1 2.0 3.7 3 1 1 4 4 4 0 Thioredoxin domain ZapB PF06005.10 062342.3_07623001_1 - 5.1 7.5 49.4 0.34 11.3 6.8 4.8 2 1 1 3 3 3 0 Cell division protein ZapB Methyltransf_21 PF05050.10 062267.1_07622001_1 - 4.3e-24 85.3 0.1 6.2e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Pkinase PF00069.23 062663.3_07621001_1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Baculo_11_kDa PF06143.9 063090.2_07622001_1 - 0.00019 20.8 2.5 0.043 13.3 0.1 3.2 3 0 0 3 3 3 2 Baculovirus 11 kDa family SID-1_RNA_chan PF13965.4 078339.1_07622001_1 - 1.6e-30 106.0 3.2 2.2e-30 105.6 3.2 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Thermopsin PF05317.9 078339.1_07622001_1 - 0.01 15.2 0.6 0.02 14.2 0.6 1.4 1 0 0 1 1 1 0 Thermopsin Endonuclease_7 PF02945.13 078402.1_07627001_1 - 1.5e-06 27.9 1.1 3e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Recombination endonuclease VII gpW PF02831.13 078402.1_07627001_1 - 0.2 11.3 0.0 0.5 10.0 0.0 1.6 1 0 0 1 1 1 0 gpW DUF2080 PF09853.7 068714.1_07623001_1 - 0.12 12.0 0.3 0.45 10.2 0.1 2.0 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) T2SS_PulS_OutS PF09691.8 068714.1_07623001_1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system pilotin lipoprotein (PulS_OutS) IlvGEDA_leader PF08046.9 061085.2_07622001_1 - 0.057 12.7 1.2 0.057 12.7 1.2 2.7 3 0 0 3 3 3 0 IlvGEDA operon leader peptide Tetraspannin PF00335.18 061085.2_07622001_1 - 0.17 11.6 19.9 0.054 13.2 12.4 2.3 1 1 1 2 2 2 0 Tetraspanin family CytochromB561_N PF09786.7 061085.2_07622001_1 - 0.29 10.0 0.9 0.55 9.1 0.9 1.5 1 1 0 1 1 1 0 Cytochrome B561, N terminal DUF996 PF06195.11 061085.2_07622001_1 - 0.32 11.2 25.6 0.047 13.8 15.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF996) DUF4728 PF15860.3 061085.2_07622001_1 - 1.7 9.2 27.3 1 9.9 6.8 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4728) DUF4834 PF16118.3 061085.2_07622001_1 - 2.1 9.2 0.0 2.1 9.2 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) Abhydrolase_9_N PF15420.4 061085.2_07622001_1 - 6.7 6.5 9.2 3.2 7.6 6.6 1.6 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus V-set PF07686.15 072557.4_07623001_1 - 0.07 13.2 0.2 0.65 10.1 0.2 2.4 1 1 0 1 1 1 0 Immunoglobulin V-set domain HSP20 PF00011.19 074185.1_07621001_1 - 1.8e-20 72.8 0.0 2.4e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family 7TM_GPCR_Srsx PF10320.7 062549.3_07623001_1 - 7.5e-10 38.5 12.8 7.5e-10 38.5 12.8 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.7 062549.3_07623001_1 - 0.0001 21.8 2.3 0.0001 21.8 2.3 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc LPG_synthase_TM PF03706.11 062549.3_07623001_1 - 1.6 8.1 10.1 0.19 11.1 3.3 2.1 1 1 1 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Globin PF00042.20 075882.3_07622001_1 - 0.011 16.2 1.9 0.011 16.1 0.4 1.8 2 0 0 2 2 2 0 Globin Ras PF00071.20 074682.1_07622001_1 - 1.8e-55 186.9 0.1 2.1e-55 186.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 074682.1_07622001_1 - 7.4e-29 100.3 0.0 1.3e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 074682.1_07622001_1 - 1.6e-11 43.8 0.0 2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 074682.1_07622001_1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.4 074682.1_07622001_1 - 0.0029 17.2 0.3 0.0046 16.6 0.3 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.14 074682.1_07622001_1 - 0.013 15.2 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Ph1570 PF09638.8 074682.1_07622001_1 - 0.017 14.8 0.4 0.035 13.8 0.1 1.7 1 1 1 2 2 2 0 Ph1570 protein AAA_21 PF13304.4 074682.1_07622001_1 - 0.12 12.0 0.3 0.64 9.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MFS_1 PF07690.14 001269646.1_07623001_1 - 5.4e-30 104.4 19.3 7.2e-30 104.0 19.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.22 063371.2_07623001_1 - 3.7e-57 194.1 24.1 4.4e-57 193.8 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 063371.2_07623001_1 - 2.4e-28 98.9 37.6 6.3e-23 81.1 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YMF19 PF02326.13 063371.2_07623001_1 - 0.02 15.5 1.6 0.038 14.6 0.1 2.4 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF788 PF05620.9 063371.2_07623001_1 - 1.3 8.8 6.2 2 8.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Glyco_transf_92 PF01697.25 067505.4_07624001_1 - 3.4e-48 164.4 5.7 4.9e-48 163.9 5.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Ly49 PF08391.8 067505.4_07624001_1 - 0.015 15.5 0.5 0.059 13.6 0.5 2.0 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region DUF3278 PF11683.6 072710.3_07623001_1 - 6.3 6.8 9.1 9.3 6.2 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Sacchrp_dh_NADP PF03435.16 071175.3_07623001_1 - 2.4e-15 56.8 0.1 3.4e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.13 071175.3_07623001_1 - 0.0013 17.8 0.1 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.15 071175.3_07623001_1 - 0.0039 17.6 0.8 0.11 13.0 0.1 2.4 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.8 071175.3_07623001_1 - 0.026 14.3 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 KR domain Peptidase_C80 PF11713.6 071175.3_07623001_1 - 0.068 13.3 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase C80 family Semialdhyde_dh PF01118.22 071175.3_07623001_1 - 0.13 12.6 0.1 0.26 11.6 0.1 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF316 PF03761.13 072514.1_07623001_1 - 1.5e-28 100.0 0.0 2e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Chymotrypsin family Peptidase-S1 Ank PF00023.28 060358.3_07622001_1 - 0.021 15.1 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.4 060358.3_07622001_1 - 0.034 14.4 0.2 0.084 13.2 0.2 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.5 060358.3_07622001_1 - 0.077 13.5 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) NlpE PF04170.10 060358.3_07622001_1 - 0.081 13.7 1.0 0.19 12.6 0.3 1.9 1 1 1 2 2 2 0 NlpE N-terminal domain Homeobox PF00046.27 062991.1_07622001_1 - 4.7e-23 80.6 4.6 7.8e-23 79.9 4.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 062991.1_07622001_1 - 0.0021 17.8 0.2 0.0055 16.5 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.6 062991.1_07622001_1 - 0.053 12.9 0.1 0.099 12.0 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Musclin PF11037.6 078067.2_07623001_1 - 0.029 14.1 0.3 0.052 13.3 0.3 1.4 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Mad3_BUB1_I PF08311.10 078067.2_07623001_1 - 0.035 14.0 0.2 0.062 13.1 0.2 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DUF268 PF03269.12 058624.3_07623001_1 - 7.9e-91 302.6 0.0 1.1e-90 302.1 0.0 1.2 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 Pkinase PF00069.23 062977.2_07622001_1 - 1.1e-18 67.4 0.0 1.4e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 062977.2_07622001_1 - 5.5e-09 35.6 0.0 6.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 062977.2_07622001_1 - 0.00046 19.5 0.0 0.005 16.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 062977.2_07622001_1 - 0.002 18.0 0.3 0.015 15.1 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.12 062977.2_07622001_1 - 0.0026 17.0 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.14 072116.2_07623001_1 - 1.9e-48 165.1 24.9 1.9e-48 165.1 24.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF647 PF04884.12 072116.2_07623001_1 - 0.022 14.3 2.7 0.05 13.1 2.7 1.5 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis CPP1-like PF11833.6 072116.2_07623001_1 - 2.7 7.4 5.8 14 5.1 0.8 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MgtC PF02308.14 072116.2_07623001_1 - 6.9 6.9 17.7 0.38 11.0 4.1 3.0 3 0 0 3 3 3 0 MgtC family DUF4956 PF16316.3 001267262.1_07622001_1 - 0.31 10.5 4.4 0.14 11.7 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4956) YccF PF03733.11 001267262.1_07622001_1 - 2.6 8.7 17.2 0.4 11.3 1.4 3.5 3 1 0 3 3 3 0 Inner membrane component domain SLC12 PF03522.13 060485.2_07622001_1 - 0.03 13.2 6.6 0.038 12.9 6.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.10 060485.2_07622001_1 - 0.051 12.5 10.7 0.059 12.3 10.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4778 PF16008.3 060485.2_07622001_1 - 0.27 11.1 9.1 0.4 10.5 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) VID27 PF08553.8 060485.2_07622001_1 - 0.29 9.5 9.1 0.34 9.3 9.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Hid1 PF12722.5 060485.2_07622001_1 - 0.31 8.9 12.9 0.37 8.7 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mitofilin PF09731.7 060485.2_07622001_1 - 0.43 9.2 16.8 0.49 9.0 16.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Rgp1 PF08737.8 060485.2_07622001_1 - 0.47 9.4 10.2 0.57 9.2 10.2 1.1 1 0 0 1 1 1 0 Rgp1 Bud13 PF09736.7 060485.2_07622001_1 - 0.52 10.6 17.2 0.7 10.1 17.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex RR_TM4-6 PF06459.10 060485.2_07622001_1 - 0.57 9.8 16.0 0.74 9.5 16.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF936 PF06075.10 060485.2_07622001_1 - 2.1 7.0 21.5 2.5 6.8 21.5 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Mlo PF03094.13 060485.2_07622001_1 - 4.4 5.4 5.4 5.7 5.1 5.4 1.2 1 0 0 1 1 1 0 Mlo family Suf PF05843.12 060485.2_07622001_1 - 4.6 7.0 14.7 5.8 6.7 14.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NST1 PF13945.4 060485.2_07622001_1 - 4.7 7.1 20.3 6.7 6.6 20.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Presenilin PF01080.15 060485.2_07622001_1 - 5.6 5.5 17.6 6.9 5.2 17.6 1.1 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.9 060485.2_07622001_1 - 8.7 4.6 21.5 10 4.3 21.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein TRA-1_regulated PF02343.14 076249.1_07622001_1 - 2.2e-22 79.4 0.0 3.9e-22 78.6 0.0 1.4 2 0 0 2 2 2 1 TRA-1 regulated protein R03H10.4 SNARE_assoc PF09335.9 077417.1_07621001_1 - 0.08 13.3 0.0 0.082 13.3 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF4503 PF14951.4 066333.1_07623001_1 - 0.033 12.5 0.4 0.11 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4503) zf-Di19 PF05605.10 001270256.1_07622001_1 - 0.48 10.6 4.8 0.21 11.7 1.1 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TMEM154 PF15102.4 068482.2_07622001_1 - 0.016 15.0 0.5 0.039 13.7 0.1 1.9 2 1 0 2 2 2 0 TMEM154 protein family MpPF26 PF07666.9 068482.2_07622001_1 - 0.032 14.2 0.5 0.032 14.2 0.5 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 Peptidase_S49_N PF08496.8 068482.2_07622001_1 - 0.033 14.1 0.3 0.033 14.1 0.3 2.8 2 1 1 3 3 3 0 Peptidase family S49 N-terminal Nucleoside_tran PF01733.16 068482.2_07622001_1 - 0.058 12.6 0.1 0.058 12.6 0.1 1.9 1 1 1 2 2 2 0 Nucleoside transporter DUF2970 PF11174.6 068482.2_07622001_1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) UCMA PF17085.3 068482.2_07622001_1 - 0.23 11.3 2.3 0.24 11.3 1.0 1.6 1 1 0 1 1 1 0 Unique cartilage matrix associated protein DUF1510 PF07423.9 068482.2_07622001_1 - 0.57 9.5 11.0 1.7 7.9 8.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) EphA2_TM PF14575.4 068482.2_07622001_1 - 0.84 10.4 2.5 5.8 7.7 1.9 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3492 PF11997.6 001313198.1_07622001_1 - 0.099 12.2 0.4 0.23 11.0 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) DUF2614 PF11023.6 074495.2_07621001_1 - 0.0047 16.9 0.7 0.0047 16.9 0.7 2.3 3 0 0 3 3 3 1 Zinc-ribbon containing domain MFP2b PF12150.6 063464.1_07623001_1 - 1.5e-111 372.9 0.2 1.9e-111 372.5 0.2 1.0 1 0 0 1 1 1 1 Cytosolic motility protein CbiQ PF02361.14 064794.1_07621001_1 - 0.23 10.9 1.5 5.6 6.4 1.5 2.0 1 1 0 1 1 1 0 Cobalt transport protein SH2 PF00017.22 077894.4_07622001_1 - 0.00012 21.9 0.0 0.00068 19.5 0.0 2.1 2 0 0 2 2 2 1 SH2 domain PID PF00640.21 077894.4_07622001_1 - 0.0003 20.7 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) zf-H2C2_2 PF13465.4 061968.2_07623001_1 - 0.086 13.2 11.7 0.3 11.5 0.4 4.3 3 0 0 3 3 3 0 Zinc-finger double domain CAF20 PF17052.3 061968.2_07623001_1 - 0.13 12.3 3.9 6 6.9 0.1 2.4 2 0 0 2 2 2 0 Cap associated factor DUF1059 PF06348.9 061968.2_07623001_1 - 0.19 11.8 3.1 0.53 10.4 0.3 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1059) zf-Di19 PF05605.10 061968.2_07623001_1 - 0.73 10.0 19.4 0.92 9.7 4.5 3.9 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DNA_RNApol_7kD PF03604.11 061968.2_07623001_1 - 1 9.0 10.9 25 4.5 0.0 4.5 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.4 061968.2_07623001_1 - 2.3 8.1 15.1 0.27 11.1 3.5 2.9 3 0 0 3 3 3 0 CpXC protein Zn_Tnp_IS1595 PF12760.5 061968.2_07623001_1 - 3 7.8 11.9 4.8 7.1 0.3 3.6 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Ribosomal_L33 PF00471.18 061968.2_07623001_1 - 3.4 8.0 9.5 8.7 6.8 0.2 3.4 3 0 0 3 3 3 0 Ribosomal protein L33 zf-RanBP PF00641.16 061968.2_07623001_1 - 4.2 6.6 12.2 0.29 10.4 0.4 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Glyco_hydro_63 PF03200.14 076734.4_07624001_1 - 3.8e-08 32.4 1.3 3.1e-05 22.8 0.0 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 63 C-terminal domain Chordopox_A15 PF05846.10 076734.4_07624001_1 - 0.11 12.6 0.0 0.52 10.4 0.0 2.2 1 0 0 1 1 1 0 Chordopoxvirus A15 protein Kunitz_BPTI PF00014.21 001129534.3_07626001_1 - 1.2e-40 137.4 64.4 2.7e-17 62.6 6.5 5.6 5 0 0 5 5 5 5 Kunitz/Bovine pancreatic trypsin inhibitor domain EGF_CA PF07645.13 001129534.3_07626001_1 - 1.4e-07 31.4 11.8 1.4e-07 31.4 11.8 4.6 3 1 0 3 3 3 1 Calcium-binding EGF domain cEGF PF12662.5 001129534.3_07626001_1 - 0.00034 20.3 5.3 0.33 10.8 0.0 3.2 2 0 0 2 2 2 2 Complement Clr-like EGF-like hEGF PF12661.5 001129534.3_07626001_1 - 0.0011 19.5 3.9 0.0011 19.5 3.9 4.2 4 0 0 4 4 4 1 Human growth factor-like EGF SSP160 PF06933.9 001129534.3_07626001_1 - 0.0037 15.4 1.2 0.0037 15.4 1.2 2.4 3 0 0 3 3 3 1 Special lobe-specific silk protein SSP160 EGF_3 PF12947.5 001129534.3_07626001_1 - 0.0044 17.0 9.1 0.0044 17.0 9.1 3.2 2 0 0 2 2 2 1 EGF domain Chordopox_A33R PF05966.10 001129534.3_07626001_1 - 9.6 5.3 10.8 4.5 6.4 0.2 2.8 3 0 0 3 3 3 0 Chordopoxvirus A33R protein PAW PF04721.15 001322511.1_07625001_1 - 2.8e-17 63.0 3.7 1.7e-05 24.6 0.2 3.4 3 0 0 3 3 3 3 PNGase C-terminal domain, mannose-binding module PAW PALP PF00291.23 061270.5_07623001_1 - 9e-31 107.2 0.0 1.3e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GKAP PF03359.11 065755.3_07622001_1 - 6.7e-21 75.1 7.5 7.9e-21 74.9 7.5 1.1 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein Peptidase_C2 PF00648.19 060996.3_07622001_1 - 8.4e-25 87.2 0.3 1e-24 87.0 0.3 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Spc97_Spc98 PF04130.11 060996.3_07622001_1 - 0.13 10.9 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 Spc97 / Spc98 family CstA PF02554.12 060996.3_07622001_1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Carbon starvation protein CstA LRR_4 PF12799.5 068284.1_07625001_1 - 3.4e-06 27.1 16.4 0.0043 17.3 0.3 5.7 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 068284.1_07625001_1 - 0.41 11.2 8.2 49 4.8 0.2 6.5 6 1 1 7 7 7 0 Leucine Rich Repeat Glyco_hydro_47 PF01532.18 069209.5_07621001_1 - 0.045 12.5 0.1 0.05 12.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 7TM_GPCR_Str PF10326.7 071258.2_07623001_1 - 3.2e-88 295.9 28.2 3.7e-88 295.7 28.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str 7TM_GPCR_Srj PF10319.7 071258.2_07623001_1 - 4e-36 124.8 22.2 5.7e-36 124.3 22.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj 7TM_GPCR_Srd PF10317.7 071258.2_07623001_1 - 4.6e-20 71.9 31.1 2.4e-19 69.5 31.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srh PF10318.7 071258.2_07623001_1 - 4.3e-14 52.1 29.7 9.2e-14 51.0 29.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.7 071258.2_07623001_1 - 9.3e-11 41.3 26.2 5.9e-10 38.7 26.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Atg14 PF10186.7 076495.5_07623001_1 - 1.6e-10 40.5 1.1 2.3e-10 39.9 1.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.10 076495.5_07623001_1 - 7.2e-05 22.2 9.9 0.0022 17.3 10.0 2.3 1 1 0 1 1 1 1 Autophagy protein Apg6 Methyltransf_22 PF13383.4 076495.5_07623001_1 - 0.033 13.6 0.2 0.059 12.8 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain WW PF00397.24 001265211.1_07621001_1 - 2e-07 30.7 0.4 3e-07 30.1 0.4 1.3 1 0 0 1 1 1 1 WW domain 7TM_GPCR_Srab PF10292.7 067718.3_07622001_1 - 6.7e-05 21.8 25.4 0.00017 20.5 25.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.16 067718.3_07622001_1 - 0.00074 18.6 26.3 0.011 14.8 26.3 2.4 1 1 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor DUF2569 PF10754.7 067718.3_07622001_1 - 0.012 15.9 0.3 0.012 15.9 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) DUF1265 PF06887.12 062157.1_07622001_1 - 4e-26 90.6 1.6 9.9e-26 89.3 1.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1265) CobT_C PF11775.6 062157.1_07622001_1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Crp PF00325.18 062157.1_07622001_2 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family THAP PF05485.10 001269687.1_07622001_1 - 4e-05 24.4 0.0 6.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 THAP domain Branch PF02485.19 001028310.3_07624001_1 - 1.8e-48 165.0 0.1 3.4e-48 164.2 0.1 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme SUR7 PF06687.10 060452.6_07622001_1 - 4.5 6.7 17.6 56 3.1 17.6 2.0 1 1 0 1 1 1 0 SUR7/PalI family MFS_1 PF07690.14 075118.2_07623001_1 - 4e-23 81.8 13.3 4e-23 81.8 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2733 PF10813.6 075118.2_07623001_1 - 0.003 17.1 0.7 0.0068 16.0 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2733) Sugar_tr PF00083.22 075118.2_07623001_1 - 0.16 10.7 29.4 0.66 8.6 6.6 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter DUF4156 PF13698.4 067095.1_07621001_1 - 0.12 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) Y_Y_Y PF07495.11 074875.3_07622001_1 - 0.041 13.7 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 Y_Y_Y domain YEATS PF03366.14 061141.4_07622001_1 - 2.1e-21 75.6 0.3 4e-21 74.7 0.3 1.5 1 0 0 1 1 1 1 YEATS family Smr PF01713.19 061988.2_07621001_1 - 0.045 14.0 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 Smr domain DUF19 PF01579.16 001268035.1_07622001_1 - 2.7e-08 33.6 4.4 3.5e-08 33.3 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF19) CPG4 PF15481.4 001268035.1_07622001_1 - 7.1e-08 32.9 2.6 9.9e-07 29.3 0.5 2.3 1 1 1 2 2 2 1 Chondroitin proteoglycan 4 DUF1397 PF07165.9 001268035.1_07622001_1 - 0.009 15.3 3.6 0.015 14.6 0.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1397) Conotoxin PF02950.15 076193.5_07621001_1 - 0.22 12.4 0.0 0.65 10.9 0.0 2.1 1 1 0 1 1 1 0 Conotoxin zf-C4H2 PF10146.7 064138.2_07622001_1 - 7.4e-52 176.4 11.4 8.6e-52 176.2 11.4 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein LUC7 PF03194.13 064138.2_07622001_1 - 2.9e-05 23.7 0.9 3.9e-05 23.3 0.9 1.1 1 0 0 1 1 1 1 LUC7 N_terminus zf-C3HC4_3 PF13920.4 064138.2_07622001_1 - 0.0011 18.6 1.7 0.0011 18.6 1.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.5 064138.2_07622001_1 - 0.0019 18.0 0.6 0.0044 16.9 0.6 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.4 064138.2_07622001_1 - 0.01 15.1 3.3 0.017 14.4 3.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.3 064138.2_07622001_1 - 0.012 16.2 0.3 0.032 14.9 0.3 1.8 1 0 0 1 1 1 0 zinc-ribbon family Syntaxin-6_N PF09177.9 064138.2_07622001_1 - 0.012 16.0 0.4 0.025 15.0 0.4 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Tup_N PF08581.8 064138.2_07622001_1 - 0.013 15.7 2.6 0.034 14.3 2.2 2.0 1 1 1 2 2 2 0 Tup N-terminal Lebercilin PF15619.4 064138.2_07622001_1 - 0.015 14.8 6.7 0.028 13.9 6.7 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease zinc_ribbon_2 PF13240.4 064138.2_07622001_1 - 0.024 14.2 3.6 0.045 13.3 3.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Prok-RING_4 PF14447.4 064138.2_07622001_1 - 0.029 14.1 1.3 0.081 12.7 1.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Lipoprotein_7 PF01540.14 064138.2_07622001_1 - 0.048 12.8 4.9 1.3 8.1 0.1 2.2 1 1 1 2 2 2 0 Adhesin lipoprotein Baculo_IE-1 PF05290.9 064138.2_07622001_1 - 0.052 13.4 0.5 0.052 13.4 0.5 2.4 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Spc7 PF08317.9 064138.2_07622001_1 - 0.068 11.9 4.1 0.091 11.5 4.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CortBP2 PF09727.7 064138.2_07622001_1 - 0.16 11.8 5.1 0.25 11.1 5.1 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 Syntaxin_2 PF14523.4 064138.2_07622001_1 - 0.17 12.1 5.6 3.8 7.8 1.7 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF3232 PF11554.6 064138.2_07622001_1 - 0.2 11.9 4.6 0.28 11.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3232) MA-Mit PF09245.8 064138.2_07622001_1 - 0.64 9.3 5.4 0.084 12.2 0.5 1.8 2 0 0 2 2 2 0 Mycoplasma arthritidis-derived mitogen zf-RING_2 PF13639.4 064138.2_07622001_1 - 3 8.1 5.9 0.6 10.3 1.5 2.1 2 0 0 2 2 2 0 Ring finger domain zf-met PF12874.5 001264595.1_07624001_1 - 0.01 16.0 0.5 0.01 16.0 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.3 001264595.1_07624001_1 - 0.12 12.1 1.7 21 4.9 0.0 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.24 001264595.1_07624001_1 - 0.82 10.1 23.7 0.19 12.1 0.4 5.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type FOXP-CC PF16159.3 001264595.1_07624001_1 - 3 8.4 7.2 27 5.4 0.6 3.8 3 0 0 3 3 3 0 FOXP coiled-coil domain GRAM PF02893.18 001307572.1_07621001_1 - 8.4e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 GRAM domain Glyco_transf_4 PF13439.4 072412.6_07621001_1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 TsaE PF02367.15 072412.6_07621001_1 - 0.14 12.0 0.3 0.2 11.5 0.2 1.3 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FBA_2 PF07735.15 001026339.1_07622001_1 - 2.8e-07 30.4 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 F-box associated CSRNP_N PF16019.3 001136286.2_07624001_1 - 2.9e-34 118.8 15.6 4.5e-26 92.0 4.5 3.0 3 0 0 3 3 3 2 Cysteine/serine-rich nuclear protein N-terminus TCR PF03638.13 001136286.2_07624001_1 - 9 6.6 14.7 52 4.1 14.7 2.0 1 1 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain OppC_N PF12911.5 001277043.1_07621001_1 - 0.2 11.6 1.2 0.28 11.1 0.4 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C F-box PF00646.31 001027272.1_07622001_1 - 1.9e-05 24.3 2.3 6.2e-05 22.6 0.9 2.4 2 0 0 2 2 2 1 F-box domain FBA_2 PF07735.15 001027272.1_07622001_1 - 0.026 14.5 1.1 0.026 14.5 1.1 3.0 3 1 0 3 3 3 0 F-box associated F-box-like PF12937.5 001027272.1_07622001_1 - 0.026 14.2 0.8 0.06 13.1 0.2 2.0 2 0 0 2 2 2 0 F-box-like APG6 PF04111.10 001029481.2_07624001_1 - 0.046 13.0 0.1 0.046 13.0 0.1 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Gly_reductase PF09338.9 001029481.2_07624001_1 - 1.7 6.8 4.4 3.2 5.9 4.4 1.3 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits SPK PF04435.16 062677.4_07622001_1 - 4.9e-21 75.0 0.8 7.5e-21 74.4 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF545) TSP_1 PF00090.17 001028512.5_07621001_1 - 3.2e-06 27.1 18.4 3.2e-06 27.1 18.4 1.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain MgtE PF01769.14 001028512.5_07621001_1 - 0.1 12.8 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Divalent cation transporter ShK PF01549.22 001029639.2_07622001_1 - 2.1e-31 108.0 49.2 5.4e-12 45.9 10.1 3.3 3 0 0 3 3 3 3 ShK domain-like DUF1510 PF07423.9 001029639.2_07622001_1 - 0.0024 17.2 4.3 0.0036 16.6 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) zf-CCCH PF00642.22 001029639.2_07622001_1 - 0.047 13.5 2.9 24 4.8 0.0 3.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Membralin PF09746.7 001029639.2_07622001_1 - 0.2 10.5 3.2 0.21 10.4 2.8 1.3 1 1 0 1 1 1 0 Tumour-associated protein SelP_N PF04592.12 001029639.2_07622001_1 - 0.37 10.0 28.4 0.25 10.6 6.8 3.1 2 1 1 3 3 3 0 Selenoprotein P, N terminal region Hid1 PF12722.5 001029639.2_07622001_1 - 0.38 8.7 14.7 0.44 8.4 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.11 001029639.2_07622001_1 - 0.57 8.6 8.3 0.58 8.6 8.3 1.1 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.10 001029639.2_07622001_1 - 0.88 7.6 7.0 1.1 7.2 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.10 001029639.2_07622001_1 - 3 7.1 11.1 3.7 6.8 11.1 1.1 1 0 0 1 1 1 0 SDA1 Fez1 PF06818.13 001038352.1_07621001_1 - 0.0038 17.6 5.5 0.0049 17.2 5.5 1.2 1 0 0 1 1 1 1 Fez1 AATF-Che1 PF13339.4 001038352.1_07621001_1 - 0.022 15.3 1.7 0.03 14.8 1.7 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor YPEB PF14620.4 001038352.1_07621001_1 - 0.026 13.8 0.5 0.03 13.6 0.5 1.1 1 0 0 1 1 1 0 YpeB sporulation IncA PF04156.12 001038352.1_07621001_1 - 0.46 10.1 9.8 0.53 9.9 9.8 1.1 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.8 001038352.1_07621001_1 - 0.91 9.6 7.1 1.2 9.2 7.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Atg14 PF10186.7 001038352.1_07621001_1 - 1.7 7.5 7.1 1.9 7.4 7.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 7TM_GPCR_Srt PF10321.7 001038362.1_07623001_1 - 3.5e-120 400.5 31.9 4.1e-120 400.3 31.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srx PF10328.7 001038362.1_07623001_1 - 0.00097 18.4 33.1 0.0013 17.9 33.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF713 PF05218.12 001038463.1_07621001_1 - 0.0071 16.0 0.2 0.0082 15.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF713) RHIM PF12721.5 001038463.1_07621001_3 - 0.033 14.5 0.8 0.067 13.5 0.8 1.5 1 0 0 1 1 1 0 RIP homotypic interaction motif SBF PF01758.14 001047593.2_07624001_1 - 3.6e-31 108.2 17.8 6e-31 107.5 17.8 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.4 001047593.2_07624001_1 - 4.3e-09 36.0 15.9 6.3e-09 35.4 15.9 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) PL48 PF15903.3 001268840.2_07627001_1 - 3.5e-34 118.2 3.0 8.9e-34 116.9 0.4 2.5 2 1 0 2 2 2 1 Filopodia upregulated, FAM65 HEAT_2 PF13646.4 001268840.2_07627001_1 - 0.003 17.8 0.1 0.0072 16.6 0.1 1.6 1 0 0 1 1 1 1 HEAT repeats DUF282 PF03380.12 001129105.3_07621001_1 - 1.1e-17 63.5 9.9 1.2e-17 63.4 8.3 2.0 2 0 0 2 2 2 1 Caenorhabditis protein of unknown function, DUF282 CX PF01705.17 001129467.1_07622001_1 - 3.3e-16 59.5 2.8 5.7e-16 58.7 1.8 1.9 2 0 0 2 2 2 1 CX module Sigma_reg_N PF13800.4 001129467.1_07622001_1 - 0.2 11.9 4.7 4.5 7.5 1.0 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal HemY_N PF07219.11 001129467.1_07622001_1 - 0.27 11.3 0.4 0.92 9.6 0.0 1.8 2 0 0 2 2 2 0 HemY protein N-terminus Sid-5 PF17204.1 001129467.1_07622001_1 - 1.1 9.4 6.2 12 6.0 2.4 2.3 2 0 0 2 2 2 0 Sid-5 family DUF3139 PF11337.6 001129467.1_07622001_1 - 1.5 9.4 8.0 4.7 7.7 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) TMEM52 PF14979.4 001129467.1_07622001_1 - 2.1 8.1 6.3 2.1 8.1 0.1 2.5 1 1 1 2 2 2 0 Transmembrane 52 DsbB PF02600.14 001262216.1_07622001_1 - 1 9.7 8.2 0.22 11.8 0.9 2.3 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB DUF2070 PF09843.7 001262216.1_07622001_1 - 5.4 5.0 8.7 6.5 4.8 8.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Invasin_D3 PF09134.8 001262991.1_07622001_1 - 0.082 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Invasin, domain 3 ATP-synt_DE PF00401.18 001263345.1_07621001_1 - 0.028 14.6 1.2 0.063 13.4 1.2 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain CDC27 PF09507.8 001263345.1_07621001_1 - 1.3 8.2 23.4 1.5 8.0 23.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SR-25 PF10500.7 001263345.1_07621001_1 - 1.8 8.0 21.1 2.2 7.7 21.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.11 001263345.1_07621001_1 - 4.8 6.9 18.6 5.4 6.7 18.6 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4551 PF15087.4 001263345.1_07621001_1 - 8.9 4.9 10.8 9.7 4.8 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Oxidored_q2 PF00420.22 001267083.1_07622001_1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7TM_GPCR_Srt PF10321.7 001276890.1_07622001_1 - 5.1e-58 196.3 15.1 6.2e-58 196.1 15.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt Spore_YhaL PF14147.4 001276890.1_07622001_1 - 0.043 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Sporulation protein YhaL GET2 PF08690.8 001276890.1_07622001_1 - 0.84 9.1 2.4 1.1 8.7 2.4 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Sec20 PF03908.11 001276890.1_07622001_1 - 0.88 9.4 4.6 8 6.3 0.3 2.3 2 0 0 2 2 2 0 Sec20 Fer4_4 PF12800.5 001276890.1_07622001_3 - 0.16 12.4 0.9 0.16 12.4 0.9 4.2 4 1 0 4 4 4 0 4Fe-4S binding domain 7TM_GPCR_Srh PF10318.7 001038417.1_07621001_1 - 9.5e-07 28.0 5.1 1e-06 27.9 5.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Sri PF10327.7 001038417.1_07621001_1 - 0.0011 18.1 3.5 0.0012 18.0 3.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Vma12 PF11712.6 001038417.1_07621001_1 - 0.088 12.7 3.4 0.046 13.6 1.6 1.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Recep_L_domain PF01030.22 001307809.2_07623001_1 - 9.9e-21 73.8 8.1 4.4e-13 49.2 1.7 3.1 2 1 0 2 2 2 2 Receptor L domain Phage_holin_3_6 PF07332.9 001026523.2_07621001_1 - 0.62 10.0 4.3 1.4 8.8 4.3 1.6 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2649 PF10854.6 001026523.2_07621001_2 - 0.078 13.2 0.2 0.098 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) RhoGAP PF00620.25 143657.5_18528001_2 - 2.2e-49 167.0 0.4 1.9e-48 164.0 0.1 2.5 2 0 0 2 2 2 1 RhoGAP domain Cation_ATPase_C PF00689.19 001014687.4_18528001_1 - 1.3e-40 138.9 9.2 1.3e-40 138.9 9.2 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.18 001014687.4_18528001_1 - 3.2e-35 121.3 13.8 1.6e-24 86.3 0.9 2.8 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.4 001014687.4_18528001_1 - 3.8e-18 65.2 0.0 8.5e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.24 001014687.4_18528001_1 - 2.9e-15 55.6 0.0 5.9e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.24 001014687.4_18528001_1 - 9.2e-15 55.4 0.1 1.1e-13 51.8 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.10 001014687.4_18528001_1 - 4.5e-07 29.7 1.6 4.5e-05 23.2 0.6 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.6 001014687.4_18528001_1 - 1.4e-05 25.3 4.4 4.4e-05 23.8 4.4 1.9 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Oxysterol_BP PF01237.16 001014687.4_18528001_1 - 0.17 10.5 0.4 0.26 9.9 0.4 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Pkinase PF00069.23 166761.2_18526001_3 - 2.7e-76 256.3 0.0 3.6e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 166761.2_18526001_3 - 7.1e-37 127.0 0.0 9.4e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 166761.2_18526001_3 - 5.9e-07 28.9 0.0 9.6e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 166761.2_18526001_3 - 2.6e-05 23.5 0.2 0.00011 21.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 166761.2_18526001_3 - 6.7e-05 22.4 0.1 0.00013 21.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.21 166761.2_18526001_3 - 0.018 14.9 0.0 0.65 9.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tyrosinase PF00264.18 166761.2_18526001_3 - 0.32 11.1 3.1 0.57 10.3 3.1 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase Pkinase_Tyr PF07714.15 079886.5_18529001_2 - 3.4e-97 324.7 0.0 4.9e-97 324.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.17 079886.5_18529001_2 - 2e-51 174.4 0.1 3.4e-51 173.7 0.1 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.23 079886.5_18529001_2 - 8.3e-45 153.1 0.0 1.7e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.4 079886.5_18529001_2 - 4.7e-20 72.0 0.0 1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain fn3 PF00041.19 079886.5_18529001_2 - 7.1e-18 64.6 7.6 8.6e-09 35.5 0.0 3.8 3 1 0 3 3 3 2 Fibronectin type III domain SAM_1 PF00536.28 079886.5_18529001_2 - 1.9e-17 63.3 0.8 3.7e-17 62.4 0.8 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 079886.5_18529001_2 - 9.9e-14 51.1 0.8 2.9e-13 49.6 0.8 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pur_ac_phosph_N PF16656.3 079886.5_18529001_2 - 5.9e-07 29.8 1.0 0.00066 20.1 0.5 2.7 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Ephrin_rec_like PF07699.11 079886.5_18529001_2 - 0.00042 19.9 7.1 0.00042 19.9 7.1 2.5 2 0 0 2 2 2 1 Putative ephrin-receptor like fn3_2 PF16893.3 079886.5_18529001_2 - 0.1 12.6 0.1 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 Fibronectin type III domain DUF2369 PF10179.7 079886.5_18529001_2 - 0.11 12.8 0.6 0.38 11.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) hEGF PF12661.5 079886.5_18529001_2 - 2.7 8.7 9.5 10 6.8 1.1 3.6 3 0 0 3 3 3 0 Human growth factor-like EGF cEGF PF12662.5 079886.5_18529001_2 - 3.2 7.6 11.9 0.98 9.3 2.4 3.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like SNF PF00209.16 143673.3_18526001_2 - 1.1e-222 740.2 44.8 1.3e-222 740.0 44.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family M_domain PF12938.5 166780.2_18529001_2 - 3e-91 305.5 49.9 3e-91 305.5 49.9 5.5 5 1 1 6 6 6 1 M domain of GW182 Ago_hook PF10427.7 166780.2_18529001_2 - 1.3e-25 90.7 22.9 1.3e-25 90.7 22.9 9.6 6 4 1 7 7 7 1 Argonaute hook UBA PF00627.29 166780.2_18529001_2 - 7.6e-07 28.8 0.1 2.2e-06 27.3 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain RRM_1 PF00076.20 166780.2_18529001_2 - 0.00046 19.8 0.0 0.00091 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 166780.2_18529001_2 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif KH_1 PF00013.27 143677.4_18529001_3 - 3.3e-25 87.5 1.8 4.7e-13 48.6 0.1 2.5 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.4 143677.4_18529001_3 - 1.7e-09 37.3 13.0 4.8e-09 35.8 13.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 143677.4_18529001_3 - 2.6e-05 23.8 11.2 5.8e-05 22.7 11.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 KH_2 PF07650.15 143677.4_18529001_3 - 0.019 14.6 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 KH domain zf-C3HC4 PF00097.23 143677.4_18529001_3 - 0.023 14.4 13.5 0.064 13.0 13.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) KH_4 PF13083.4 143677.4_18529001_3 - 0.057 13.2 0.0 7 6.5 0.0 2.3 2 0 0 2 2 2 0 KH domain zf-RING_UBOX PF13445.4 143677.4_18529001_3 - 1.5 8.8 6.6 1.4 8.8 5.0 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.4 143677.4_18529001_3 - 6.1 6.5 8.5 13 5.4 8.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.4 079891.3_18525001_3 - 5.5e-15 54.9 24.2 3.2e-07 30.4 0.2 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.24 079891.3_18525001_3 - 1.2e-14 53.7 26.4 0.00052 20.2 0.4 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 079891.3_18525001_3 - 3.4e-10 39.7 22.9 0.047 14.4 0.3 5.3 4 0 0 4 4 4 4 C2H2-type zinc finger Transpos_assoc PF13963.4 079891.3_18525001_3 - 0.00021 21.6 3.5 0.018 15.4 0.3 3.2 2 1 0 2 2 2 1 Transposase-associated domain zf-C2H2_jaz PF12171.6 079891.3_18525001_3 - 0.097 12.9 16.1 0.32 11.2 1.4 4.3 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.16 079891.3_18525001_3 - 0.11 12.4 2.4 7 6.6 0.1 4.2 4 0 0 4 4 4 0 XPA protein N-terminal zinc_ribbon_9 PF14369.4 079891.3_18525001_3 - 0.2 11.8 3.9 4.7 7.4 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-met PF12874.5 079891.3_18525001_3 - 0.93 9.8 8.6 1.8 8.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.19 079891.3_18525001_3 - 1.9 8.6 7.9 20 5.4 7.9 2.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain CCAP PF11105.6 079891.3_18525001_3 - 2 8.3 5.4 2.6 7.9 0.7 2.6 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a CHORD PF04968.10 079891.3_18525001_3 - 2.9 8.5 11.5 17 6.1 2.4 3.7 2 1 1 3 3 3 0 CHORD zf-C2H2_11 PF16622.3 079891.3_18525001_3 - 3.8 7.2 7.2 9.8 5.9 0.5 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Pkinase PF00069.23 166759.2_18525001_1 - 2.9e-71 239.8 0.0 4.1e-70 236.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 166759.2_18525001_1 - 5.2e-32 111.0 0.0 1e-30 106.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 166759.2_18525001_1 - 4.5e-07 29.3 0.0 7.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 166759.2_18525001_1 - 2.8e-05 23.4 0.1 0.00014 21.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 166759.2_18525001_1 - 0.005 16.3 0.1 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.21 166759.2_18525001_1 - 0.034 13.9 0.0 0.57 9.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tyrosinase PF00264.18 166759.2_18525001_1 - 0.25 11.4 3.1 0.45 10.6 3.1 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase PurA PF04845.11 166769.2_18526001_3 - 3e-107 356.8 0.3 3.7e-107 356.5 0.3 1.1 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein EFG_C PF00679.22 166769.2_18526001_3 - 0.037 13.9 0.0 9.4 6.2 0.0 2.9 3 0 0 3 3 3 0 Elongation factor G C-terminus SH3_2 PF07653.15 166743.3_18523001_1 - 3.2e-21 74.6 1.2 1.9e-10 40.2 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH2 PF00017.22 166743.3_18523001_1 - 1.2e-19 69.9 0.0 2.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.26 166743.3_18523001_1 - 2.6e-17 62.0 1.0 2.3e-13 49.4 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 166743.3_18523001_1 - 5.5e-16 58.0 0.1 1.5e-09 37.4 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.4 166743.3_18523001_1 - 6.2e-05 23.3 2.7 0.00014 22.2 0.1 2.6 3 0 0 3 3 3 1 Helically-extended SH3 domain PDZ PF00595.22 143676.2_18526001_3 - 2.4e-13 50.1 0.6 3.1e-10 40.1 0.4 2.6 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 143676.2_18526001_3 - 6.1e-07 29.5 0.8 0.00014 21.9 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDE8 PF08629.8 143676.2_18526001_3 - 0.69 9.8 4.7 0.23 11.4 0.5 2.5 2 0 0 2 2 2 0 PDE8 phosphodiesterase DUF3051 PF11252.6 001272137.1_18525001_3 - 0.012 15.1 0.6 0.026 14.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) PDE8 PF08629.8 001272137.1_18525001_3 - 0.73 9.7 4.7 0.2 11.6 0.5 2.3 2 0 0 2 2 2 0 PDE8 phosphodiesterase ABC_membrane_2 PF06472.13 166736.4_18527001_2 - 2.2e-96 322.4 7.7 2.2e-96 322.4 7.7 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.25 166736.4_18527001_2 - 7.3e-18 65.3 0.0 1.6e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.4 166736.4_18527001_2 - 0.00019 21.2 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.17 166736.4_18527001_2 - 0.005 16.2 0.0 0.49 9.7 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.4 166736.4_18527001_2 - 0.016 15.6 0.1 0.016 15.6 0.1 2.4 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.4 166736.4_18527001_2 - 0.049 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SurA_N_3 PF13624.4 166736.4_18527001_2 - 0.054 13.1 0.3 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain Membr_traf_MHD PF10540.7 166794.3_18529001_3 - 4.3e-50 169.7 2.1 4.3e-50 169.7 2.1 3.3 3 1 1 4 4 4 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.28 166794.3_18529001_3 - 2.8e-43 146.3 1.0 3.6e-27 94.5 0.3 3.0 2 0 0 2 2 2 2 C2 domain DUF1041 PF06292.15 166794.3_18529001_3 - 3.2e-34 117.3 4.0 1.3e-33 115.4 0.2 3.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.20 166794.3_18529001_3 - 8.7e-10 38.2 5.2 2e-09 37.1 5.2 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PAX PF00292.16 001014701.2_18529001_2 - 1.2e-69 231.9 0.4 2e-69 231.2 0.4 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.4 001014701.2_18529001_2 - 0.00018 21.1 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.4 001014701.2_18529001_2 - 0.0017 18.8 0.0 0.29 11.7 0.0 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_IS1 PF12759.5 001014701.2_18529001_2 - 0.015 14.8 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain HTH_28 PF13518.4 001014701.2_18529001_2 - 0.025 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Ski_Sno PF02437.15 001169358.2_18526001_1 - 1.6e-38 130.7 2.1 3.7e-38 129.5 2.1 1.6 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.8 001169358.2_18526001_1 - 3.8e-29 100.7 2.5 3.8e-29 100.7 2.5 1.9 2 0 0 2 2 2 1 c-SKI Smad4 binding domain Jas PF16135.3 001169358.2_18526001_1 - 0.096 12.7 0.5 0.3 11.1 0.5 1.8 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling 7tm_3 PF00003.20 001272148.1_18527001_2 - 5.5e-26 91.7 0.9 1.1e-25 90.7 0.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.12 001272148.1_18527001_2 - 3.2e-10 39.7 11.9 1.4e-09 37.6 11.9 2.2 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR ANF_receptor PF01094.26 001272148.1_18527001_3 - 6.7e-106 354.2 0.3 8.8e-106 353.8 0.3 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.4 001272148.1_18527001_3 - 4.1e-11 43.0 0.0 6.1e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.20 001272148.1_18527001_3 - 1.5e-07 31.4 1.7 2.8e-07 30.5 1.7 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR HNF-1A_C PF04813.10 001297790.1_18525001_1 - 0.0034 18.0 0.7 0.0065 17.1 0.7 1.4 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus ATP-synt_ab PF00006.23 001297790.1_18525001_3 - 2.1e-64 216.9 0.0 3.2e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.21 001297790.1_18525001_3 - 1.3e-22 80.0 0.7 2.4e-22 79.1 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.16 001297790.1_18525001_3 - 0.0065 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF258 PF03193.14 001297790.1_18525001_3 - 0.019 14.8 0.1 0.053 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NB-ARC PF00931.20 001297790.1_18525001_3 - 0.072 12.0 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.4 001297790.1_18525001_3 - 0.14 12.4 0.6 0.37 11.0 0.2 1.9 2 0 0 2 2 2 0 AAA domain RecO_C PF02565.13 123745.1_18521120_1 - 0.13 12.0 0.2 0.15 11.7 0.2 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal WRW PF10206.7 003114.2_18522120_3 - 5.5e-24 84.3 9.3 1.1e-20 73.7 1.1 2.7 1 1 1 2 2 2 2 Mitochondrial F1F0-ATP synthase, subunit f WRW PF10206.7 073623.1_18521120_2 - 1.2e-24 86.5 9.8 7.4e-22 77.5 9.8 2.5 1 1 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Galactosyl_T PF01762.19 130477.4_18524001_1 - 1.9e-30 106.0 0.0 2.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Peptidase_M14 PF00246.22 166846.5_18529001_3 - 5.6e-159 528.4 0.0 2.7e-81 273.4 0.0 4.1 4 1 0 4 4 4 3 Zinc carboxypeptidase CarboxypepD_reg PF13620.4 166846.5_18529001_3 - 1.9e-44 149.7 0.0 5e-14 52.2 0.0 4.5 4 0 0 4 4 4 4 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.4 166846.5_18529001_3 - 4.9e-20 71.2 0.0 1.1e-05 25.2 0.0 4.6 4 0 0 4 4 4 4 CarboxypepD_reg-like domain PEGA PF08308.9 166846.5_18529001_3 - 0.00024 20.8 0.0 6.4 6.6 0.0 4.5 4 0 0 4 4 4 2 PEGA domain DUF1416 PF07210.10 166846.5_18529001_3 - 0.0024 17.6 0.1 0.76 9.6 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1416) AstE_AspA PF04952.12 166846.5_18529001_3 - 0.0041 16.1 0.2 0.26 10.2 0.0 2.3 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.22 176679.3_18529001_1 - 5.3e-159 528.5 0.0 2.5e-81 273.5 0.0 4.1 4 1 0 4 4 4 3 Zinc carboxypeptidase CarboxypepD_reg PF13620.4 176679.3_18529001_1 - 1.6e-44 149.9 0.0 4.8e-14 52.3 0.0 4.5 4 0 0 4 4 4 4 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.4 176679.3_18529001_1 - 4.2e-20 71.4 0.0 1e-05 25.3 0.0 4.6 4 0 0 4 4 4 4 CarboxypepD_reg-like domain AstE_AspA PF04952.12 176679.3_18529001_1 - 0.0001 21.4 0.2 0.0071 15.3 0.0 2.3 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family PEGA PF08308.9 176679.3_18529001_1 - 0.00026 20.7 0.2 6.2 6.7 0.0 4.5 5 0 0 5 5 5 2 PEGA domain DUF1416 PF07210.10 176679.3_18529001_1 - 0.0022 17.7 0.1 0.73 9.6 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1416) Dioxygenase_C PF00775.19 176679.3_18529001_1 - 0.018 14.3 0.3 1e+02 2.1 0.0 4.7 5 0 0 5 5 5 0 Dioxygenase NAP PF00956.16 130515.3_18523001_1 - 1.9e-67 227.2 0.0 2.2e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Peptidase_S28 PF05577.10 130515.3_18523001_1 - 0.16 10.6 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 MFS_1 PF07690.14 130520.4_18525001_1 - 5.4e-23 81.4 55.4 6.8e-23 81.0 6.7 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 130520.4_18525001_1 - 9.1e-16 57.6 6.8 9.1e-16 57.6 6.8 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter tRNA_Me_trans PF03054.14 144382.4_18523001_1 - 5.2e-137 456.3 0.0 6.1e-137 456.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.15 144382.4_18523001_1 - 2.3e-07 30.1 0.0 4e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.12 144382.4_18523001_1 - 0.00011 21.7 0.0 0.0027 17.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.19 144382.4_18523001_1 - 0.0025 17.4 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.18 144382.4_18523001_1 - 0.036 13.7 1.1 0.44 10.2 1.1 2.3 1 1 0 1 1 1 0 PP-loop family QueC PF06508.11 144382.4_18523001_1 - 0.04 13.3 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.17 144382.4_18523001_1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.9 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Myb_DNA-bind_5 PF13873.4 166882.3_18527001_3 - 8.7e-16 57.6 3.2 8.7e-16 57.6 3.2 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.4 166882.3_18527001_3 - 0.00064 19.9 2.0 0.0016 18.6 2.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pyr_redox_2 PF07992.12 166924.3_18526001_1 - 1.5e-47 162.2 0.5 2.2e-47 161.6 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.24 166924.3_18526001_1 - 2e-15 56.3 0.0 5.8e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.25 166924.3_18526001_1 - 1.7e-13 50.8 3.4 7.7e-13 48.7 1.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.4 166924.3_18526001_1 - 2.2e-08 33.5 0.2 2.8e-07 30.0 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.4 166924.3_18526001_1 - 5.4e-06 26.1 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.4 166924.3_18526001_1 - 0.00083 19.8 0.0 0.0055 17.1 0.0 2.3 2 0 0 2 2 2 1 Reductase C-terminal HI0933_like PF03486.12 166924.3_18526001_1 - 0.052 12.1 0.2 7.1 5.1 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Dockerin_1 PF00404.16 166924.3_18526001_1 - 0.22 11.4 0.6 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Dockerin type I repeat Ig_3 PF13927.4 001258567.2_18529001_3 - 2.9e-128 418.6 27.0 1.5e-10 41.4 0.0 14.0 13 0 0 13 13 13 13 Immunoglobulin domain I-set PF07679.14 001258567.2_18529001_3 - 3e-116 379.6 0.7 7.6e-15 54.6 0.0 13.7 13 0 0 13 13 13 12 Immunoglobulin I-set domain Laminin_B PF00052.16 001258567.2_18529001_3 - 8.5e-104 342.7 0.6 2.8e-35 121.0 0.1 4.6 5 1 1 6 6 5 3 Laminin B (Domain IV) ig PF00047.23 001258567.2_18529001_3 - 4.5e-94 308.6 5.3 1.4e-06 28.2 0.0 14.0 13 0 0 13 13 13 13 Immunoglobulin domain Ig_2 PF13895.4 001258567.2_18529001_3 - 1.7e-90 297.3 22.7 2.5e-08 34.0 0.1 14.1 13 0 0 13 13 13 12 Immunoglobulin domain Laminin_G_2 PF02210.22 001258567.2_18529001_3 - 8.4e-63 210.5 0.0 2.1e-24 86.3 0.0 3.8 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.21 001258567.2_18529001_3 - 7.7e-62 207.2 0.0 1.2e-21 77.2 0.0 3.7 3 0 0 3 3 3 3 Laminin G domain Ldl_recept_a PF00057.16 001258567.2_18529001_3 - 1.8e-61 203.9 213.4 8.7e-12 44.9 7.5 12.2 12 0 0 12 12 9 9 Low-density lipoprotein receptor domain class A V-set PF07686.15 001258567.2_18529001_3 - 3.1e-38 130.1 30.2 0.0033 17.4 0.0 19.0 13 7 3 17 17 17 10 Immunoglobulin V-set domain Laminin_EGF PF00053.22 001258567.2_18529001_3 - 1.3e-13 50.7 90.2 3.9e-07 30.0 15.9 16.1 10 5 3 13 13 11 8 Laminin EGF domain Izumo-Ig PF16706.3 001258567.2_18529001_3 - 1.1e-11 44.4 8.6 3.2 7.7 0.0 10.6 12 0 0 12 12 11 2 Izumo-like Immunoglobulin domain EGF PF00008.25 001258567.2_18529001_3 - 3.9e-07 30.1 5.4 3.9e-07 30.1 5.4 16.8 18 0 0 18 18 12 4 EGF-like domain Trypan_PARP PF05887.9 001258567.2_18529001_3 - 3e-05 24.0 35.6 3e-05 24.0 35.6 2.1 2 0 0 2 2 1 1 Procyclic acidic repetitive protein (PARP) C1-set PF07654.13 001258567.2_18529001_3 - 0.0071 16.7 2.5 4.6 7.7 0.0 5.2 5 0 0 5 5 4 1 Immunoglobulin C1-set domain SEA PF01390.18 001258567.2_18529001_3 - 0.051 13.7 1.1 0.13 12.5 1.1 1.6 1 0 0 1 1 1 0 SEA domain Ig_3 PF13927.4 001258563.2_18529001_3 - 1.6e-128 419.4 27.0 1.5e-10 41.4 0.0 14.0 13 0 0 13 13 13 13 Immunoglobulin domain I-set PF07679.14 001258563.2_18529001_3 - 1.7e-116 380.4 0.7 7.2e-15 54.7 0.0 13.7 13 0 0 13 13 13 12 Immunoglobulin I-set domain Laminin_B PF00052.16 001258563.2_18529001_3 - 6.7e-104 343.0 0.5 2.7e-35 121.1 0.1 4.6 5 1 1 6 6 6 3 Laminin B (Domain IV) ig PF00047.23 001258563.2_18529001_3 - 2.5e-94 309.5 5.3 1.4e-06 28.3 0.0 14.1 13 0 0 13 13 13 13 Immunoglobulin domain Ig_2 PF13895.4 001258563.2_18529001_3 - 9.7e-91 298.1 22.7 2.3e-08 34.1 0.1 14.0 13 0 0 13 13 13 12 Immunoglobulin domain Laminin_G_2 PF02210.22 001258563.2_18529001_3 - 7.2e-63 210.7 0.0 2.1e-24 86.4 0.0 3.8 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.21 001258563.2_18529001_3 - 6.6e-62 207.4 0.0 1.1e-21 77.3 0.0 3.7 3 0 0 3 3 3 3 Laminin G domain Ldl_recept_a PF00057.16 001258563.2_18529001_3 - 2.8e-53 177.7 199.2 8.3e-12 45.0 7.5 11.3 11 0 0 11 11 8 8 Low-density lipoprotein receptor domain class A V-set PF07686.15 001258563.2_18529001_3 - 1.4e-38 131.2 30.2 0.0032 17.5 0.0 19.0 13 7 3 17 17 17 10 Immunoglobulin V-set domain Laminin_EGF PF00053.22 001258563.2_18529001_3 - 8.1e-14 51.4 90.2 3.8e-07 30.0 15.9 16.0 10 5 3 13 13 11 8 Laminin EGF domain Izumo-Ig PF16706.3 001258563.2_18529001_3 - 1.1e-11 44.5 8.8 4 7.4 0.0 10.7 12 0 0 12 12 11 2 Izumo-like Immunoglobulin domain EGF PF00008.25 001258563.2_18529001_3 - 3.8e-07 30.2 5.4 3.8e-07 30.2 5.4 16.8 18 0 0 18 18 12 4 EGF-like domain Trypan_PARP PF05887.9 001258563.2_18529001_3 - 2.8e-05 24.0 35.6 2.8e-05 24.0 35.6 2.1 2 0 0 2 2 1 1 Procyclic acidic repetitive protein (PARP) C1-set PF07654.13 001258563.2_18529001_3 - 0.0058 16.9 2.5 4.4 7.7 0.0 5.2 5 0 0 5 5 4 1 Immunoglobulin C1-set domain SEA PF01390.18 001258563.2_18529001_3 - 0.049 13.8 1.1 0.12 12.5 1.1 1.6 1 0 0 1 1 1 0 SEA domain Ig_3 PF13927.4 080319.5_18529001_1 - 3.6e-43 145.9 10.2 6.6e-10 39.3 0.0 6.2 6 0 0 6 6 6 5 Immunoglobulin domain I-set PF07679.14 080319.5_18529001_1 - 9.9e-36 121.6 4.0 6.5e-09 35.6 0.0 6.1 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.4 080319.5_18529001_1 - 1.3e-30 105.4 1.3 1.9e-08 34.4 0.1 5.7 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.23 080319.5_18529001_1 - 1.7e-20 72.8 10.1 0.00014 21.8 0.0 6.7 6 1 0 6 6 6 5 Immunoglobulin domain C2-set_2 PF08205.10 080319.5_18529001_1 - 7.5e-16 57.9 14.9 2.8e-15 56.0 0.0 5.9 6 2 1 7 7 7 1 CD80-like C2-set immunoglobulin domain V-set PF07686.15 080319.5_18529001_1 - 6.3e-11 42.3 3.9 5.3e-05 23.2 0.0 5.3 4 2 0 4 4 4 2 Immunoglobulin V-set domain Marek_A PF02124.13 080319.5_18529001_1 - 0.00028 20.7 1.0 0.69 9.6 0.2 2.8 2 0 0 2 2 2 2 Marek's disease glycoprotein A C1-set PF07654.13 080319.5_18529001_1 - 0.00091 19.5 7.2 0.23 11.8 0.0 4.7 5 0 0 5 5 5 1 Immunoglobulin C1-set domain V-set_CD47 PF08204.9 080319.5_18529001_1 - 0.0012 18.7 0.4 0.06 13.2 0.0 3.4 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain PKD_3 PF16820.3 080319.5_18529001_1 - 0.0084 15.7 0.0 2.5 7.8 0.0 3.3 3 0 0 3 3 3 1 PKD-like domain DUF2070 PF09843.7 130699.2_18524001_2 - 2.1 6.4 4.6 2.9 5.9 4.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Forkhead PF00250.16 166991.3_18527001_2 - 1e-23 83.3 0.0 2.5e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain CCDC71L PF15374.4 166991.3_18527001_2 - 3 6.9 14.3 0.065 12.4 6.9 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L Mit_proteolip PF08039.9 166991.3_18527001_3 - 0.052 13.7 5.1 0.14 12.4 5.1 1.7 1 0 0 1 1 1 0 Mitochondrial proteolipid Ras PF00071.20 206622.4_18529001_1 - 1e-23 83.6 0.6 2.7e-23 82.2 0.6 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.11 206622.4_18529001_1 - 0.00015 21.8 0.0 0.00015 21.8 0.0 2.5 4 0 0 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase DUF258 PF03193.14 206622.4_18529001_1 - 0.00019 21.3 6.5 0.046 13.5 0.0 3.6 2 1 1 3 3 3 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 206622.4_18529001_1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.19 206622.4_18529001_1 - 0.024 14.0 0.6 0.22 10.8 0.6 2.4 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.4 206622.4_18529001_1 - 0.029 14.0 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L33 PF00471.18 080242.4_18521001_2 - 0.0088 16.3 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L33 DUF4547 PF15080.4 080242.4_18521001_2 - 0.034 13.7 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) 7tm_1 PF00001.19 131955.2_18528001_1 - 1.9e-20 73.1 14.7 2.8e-10 39.8 1.7 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.7 131955.2_18528001_1 - 1.8e-18 66.8 19.2 1.3e-10 41.0 8.9 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.7 131955.2_18528001_1 - 5.1e-06 25.9 20.4 0.00099 18.4 3.3 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx HTH_Tnp_1 PF01527.18 131955.2_18528001_1 - 0.025 14.7 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 Transposase zf-H2C2_2 PF13465.4 080338.5_18529001_3 - 3e-11 43.1 25.3 5.2e-08 32.9 1.5 4.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.24 080338.5_18529001_3 - 0.00027 21.1 35.9 0.0025 18.1 1.8 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 080338.5_18529001_3 - 0.0023 18.4 36.2 0.0097 16.5 0.8 5.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.5 080338.5_18529001_3 - 9.2 6.7 18.4 0.94 9.8 6.5 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.4 167027.4_18529001_1 - 2e-11 43.7 25.3 4.8e-08 33.0 1.5 5.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.24 167027.4_18529001_1 - 0.00017 21.7 35.9 0.0023 18.2 1.8 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 167027.4_18529001_1 - 0.0012 19.4 36.2 0.0089 16.6 0.8 5.5 4 0 0 4 4 4 3 C2H2-type zinc finger DUF5134 PF17197.2 167027.4_18529001_1 - 0.69 9.7 6.2 0.19 11.5 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) Beach PF02138.16 001144686.2_18529001_3 - 1.3e-122 408.4 0.1 2.4e-122 407.5 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.3 001144686.2_18529001_3 - 4.4e-111 370.4 5.4 1.2e-110 369.0 5.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) DUF1088 PF06469.9 001144686.2_18529001_3 - 2.2e-75 251.8 2.4 4.7e-75 250.8 2.4 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.4 001144686.2_18529001_3 - 4e-27 94.1 0.0 1.4e-26 92.3 0.0 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.30 001144686.2_18529001_3 - 1.4e-08 35.1 3.9 0.083 13.7 0.3 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat SK_channel PF03530.12 080339.3_18528001_3 - 8.4e-49 164.2 0.4 8.4e-49 164.2 0.4 2.3 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.14 080339.3_18528001_3 - 1.8e-36 124.1 6.1 4.6e-36 122.8 6.1 1.8 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.14 080339.3_18528001_3 - 3.7e-12 45.9 0.9 3.7e-12 45.9 0.9 1.9 2 0 0 2 2 2 1 Ion channel DUF4446 PF14584.4 080339.3_18528001_3 - 2.1 8.2 6.1 1.6 8.6 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) EF-hand_7 PF13499.4 132005.3_18523001_1 - 0.00017 21.8 0.0 0.081 13.3 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair Peptidase_M14 PF00246.22 132031.3_18524001_2 - 5e-89 298.8 0.1 6.8e-89 298.3 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.14 132031.3_18524001_2 - 6.7e-06 26.3 0.1 1.5e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide AstE_AspA PF04952.12 132031.3_18524001_2 - 0.0044 16.0 0.0 0.0061 15.5 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family SNARE PF05739.17 132031.3_18524001_2 - 1.4 8.8 3.4 1.7 8.6 2.1 1.9 2 0 0 2 2 2 0 SNARE domain DUF1443 PF07280.9 132031.3_18524001_2 - 3.5 7.4 8.8 7.4 6.3 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) PHD PF00628.27 132083.4_18527001_1 - 4.4e-18 64.8 22.7 6.3e-11 41.9 10.6 2.5 2 0 0 2 2 2 2 PHD-finger PHF12_MRG_bd PF16737.3 132083.4_18527001_1 - 2.7e-17 62.1 1.9 6e-17 60.9 1.9 1.6 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain C1_1 PF00130.20 132083.4_18527001_1 - 7e-05 22.5 14.1 0.002 17.9 2.8 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FHA PF00498.24 132083.4_18527001_1 - 0.005 17.0 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain PHD_2 PF13831.4 132083.4_18527001_1 - 0.0062 15.9 16.5 0.022 14.1 0.1 3.2 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.4 132083.4_18527001_1 - 0.16 12.1 9.7 0.97 9.6 1.6 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.4 132083.4_18527001_1 - 0.27 10.7 9.2 0.81 9.2 1.2 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H_2 PF13832.4 132083.4_18527001_1 - 2 8.4 8.4 11 6.0 1.9 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain Pkinase PF00069.23 167080.2_18527001_3 - 2.4e-42 145.0 2.3 2.5e-24 85.9 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.15 167080.2_18527001_3 - 3.7e-15 55.8 3.8 1e-13 51.0 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase TFIIA PF03153.11 167080.2_18527001_3 - 0.0019 18.2 29.6 0.0019 18.2 29.6 2.5 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.6 167080.2_18527001_3 - 0.0025 17.3 25.8 0.0025 17.3 25.8 3.2 3 0 0 3 3 3 1 Spt20 family Inhibitor_I71 PF12628.5 167080.2_18527001_3 - 1.7 8.3 10.8 0.33 10.6 0.1 2.4 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Ndc1_Nup PF09531.8 167080.2_18527001_3 - 2.6 6.5 13.8 0.28 9.7 8.3 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CBM_25 PF03423.11 167080.2_18527001_3 - 2.8 8.1 10.0 1.5 8.9 0.3 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Ctr PF04145.13 132108.3_18525001_3 - 3.3e-36 125.0 2.7 5.8e-36 124.2 2.7 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Prenyltransf PF01255.17 132197.3_18523001_2 - 1e-75 254.0 0.1 1.4e-75 253.5 0.1 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Phospholip_A2_2 PF05826.10 132226.3_18523001_1 - 5.8e-35 119.2 3.4 1e-34 118.4 3.4 1.4 1 0 0 1 1 1 1 Phospholipase A2 Guanylate_kin PF00625.19 206652.2_18528001_2 - 2.7e-43 147.6 0.2 6e-43 146.5 0.0 1.7 2 0 0 2 2 2 1 Guanylate kinase SH3_2 PF07653.15 206652.2_18528001_2 - 1.3e-12 47.0 0.0 2.6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.22 206652.2_18528001_2 - 2.3e-12 47.0 0.4 4.5e-12 46.0 0.4 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.14 206652.2_18528001_2 - 1.2e-06 28.0 0.0 2.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 L27 domain SH3_1 PF00018.26 206652.2_18528001_2 - 6.8e-06 25.5 0.0 1.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PDZ_2 PF13180.4 206652.2_18528001_2 - 7.9e-05 22.8 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.4 206652.2_18528001_2 - 0.002 17.8 0.1 0.0042 16.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Sec66 PF09802.7 206652.2_18528001_2 - 0.052 13.0 1.5 0.4 10.1 0.0 2.7 3 0 0 3 3 3 0 Preprotein translocase subunit Sec66 TFIIA PF03153.11 206652.2_18528001_2 - 4.2 7.1 15.9 8.4 6.1 15.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPP1-like PF11833.6 167155.3_18522001_1 - 3.1 7.3 5.8 6.9 6.1 0.2 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TFIIA PF03153.11 132257.2_18523001_2 - 0.18 11.7 16.5 0.23 11.3 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Palm_thioest PF02089.13 167166.4_18523001_2 - 9.5e-101 336.5 0.1 1.2e-100 336.2 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.18 167166.4_18523001_2 - 0.0032 17.0 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.23 167188.2_18528001_1 - 2.1e-66 223.9 0.0 5e-66 222.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 167188.2_18528001_1 - 2.1e-30 105.8 0.0 4.6e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 167188.2_18528001_1 - 0.0015 17.8 0.0 0.0039 16.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.9 167188.2_18528001_1 - 0.0079 15.1 0.6 0.47 9.3 0.1 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 DUF423 PF04241.13 001144710.3_18522001_1 - 1.3e-15 57.2 0.6 3.4e-15 55.9 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF423) HECT PF00632.23 132347.2_18524001_1 - 2.3e-102 342.5 0.0 3e-102 342.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Lipase PF00151.17 078547.3_18524001_3 - 3e-92 309.4 0.2 4.5e-92 308.8 0.2 1.3 1 0 0 1 1 1 1 Lipase DUF4766 PF15973.3 132386.3_18523001_1 - 1.5e-35 122.2 24.8 1.5e-35 122.2 24.8 4.3 2 2 1 3 3 3 1 Domain of unknown function (DUF4766) DEC-1_N PF04625.11 132386.3_18523001_1 - 0.44 9.4 2.5 0.6 8.9 2.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Adeno_terminal PF02459.13 132391.3_18524001_3 - 0.3 9.3 0.6 0.51 8.5 0.6 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein BAT2_N PF07001.9 132403.5_18529001_3 - 2.9e-48 164.8 23.5 2.9e-48 164.8 23.5 15.8 8 5 8 18 18 18 2 BAT2 N-terminus IMPDH PF00478.23 079907.7_18525001_1 - 1.1e-137 458.5 2.6 1.4e-137 458.2 2.6 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.26 079907.7_18525001_1 - 5.4e-11 42.6 0.0 0.0003 21.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.13 079907.7_18525001_1 - 1.3e-09 37.8 0.6 7.2e-06 25.5 0.6 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.16 079907.7_18525001_1 - 2.3e-09 36.6 0.9 3.7e-09 35.9 0.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.19 079907.7_18525001_1 - 2.1e-05 23.9 3.3 0.00075 18.9 0.4 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein NanE PF04131.12 079907.7_18525001_1 - 0.00026 20.1 0.4 0.00054 19.1 0.4 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.12 079907.7_18525001_1 - 0.00035 19.9 0.6 0.00068 18.9 0.6 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.15 079907.7_18525001_1 - 0.0021 17.1 1.9 0.0038 16.3 1.9 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF1273 PF06908.9 079907.7_18525001_1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) DHO_dh PF01180.19 079907.7_18525001_1 - 0.061 12.4 1.0 0.14 11.2 1.0 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase SNARE_assoc PF09335.9 167244.3_18524001_1 - 1.1e-07 32.2 1.0 4.7e-07 30.2 0.3 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein MerE PF05052.10 167244.3_18524001_1 - 0.14 12.0 0.5 0.5 10.2 0.2 2.1 2 0 0 2 2 2 0 MerE protein CCDC106 PF15794.3 167244.3_18524001_1 - 0.3 10.6 7.3 0.51 9.9 7.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Pkinase_Tyr PF07714.15 078559.3_18529001_2 - 1.2e-91 306.5 0.0 2.1e-91 305.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.19 078559.3_18529001_2 - 1.8e-51 172.3 1.6 1.9e-12 47.2 0.9 9.4 9 1 0 9 9 9 6 Fibronectin type III domain Pkinase PF00069.23 078559.3_18529001_2 - 7.2e-37 127.0 0.0 1.2e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pur_ac_phosph_N PF16656.3 078559.3_18529001_2 - 6.2e-06 26.6 3.4 1.1 9.7 0.1 6.1 7 0 0 7 7 7 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.8 078559.3_18529001_2 - 0.01 16.0 0.0 0.52 10.5 0.0 3.6 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III CarboxypepD_reg PF13620.4 078559.3_18529001_2 - 0.061 13.5 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain SGL PF08450.10 078559.3_18529001_2 - 0.18 11.2 0.0 0.47 9.9 0.0 1.7 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region zf-C2H2_4 PF13894.4 132457.2_18529001_1 - 2 9.3 33.3 1.9 9.4 0.8 6.5 5 0 0 5 5 5 0 C2H2-type zinc finger Serglycin PF04360.10 132457.2_18529001_3 - 1.9 8.3 7.2 11 5.9 7.2 2.3 1 0 0 1 1 1 0 Serglycin EF-hand_7 PF13499.4 132471.5_18529001_1 - 1.2e-21 76.8 0.6 8.9e-16 58.0 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 132471.5_18529001_1 - 3.3e-20 69.9 1.5 3e-06 26.2 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.4 132471.5_18529001_1 - 1.1e-15 56.0 1.2 0.00019 21.0 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.4 132471.5_18529001_1 - 1.1e-13 49.9 5.3 6.3e-05 22.2 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.4 132471.5_18529001_1 - 4.1e-13 48.8 0.2 3.2e-05 23.5 0.5 3.3 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 132471.5_18529001_1 - 0.04 14.1 0.1 0.04 14.1 0.1 4.4 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Peptidase_M16_M PF16187.3 132529.4_18529001_1 - 2.9e-71 239.9 2.0 5e-71 239.1 2.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.18 132529.4_18529001_1 - 8.5e-34 116.6 0.2 6.7e-32 110.4 0.1 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 132529.4_18529001_1 - 6.9e-32 110.8 0.9 2.1e-15 57.1 0.1 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain SpoIIIAH PF12685.5 132529.4_18529001_1 - 0.056 13.1 5.5 0.48 10.1 0.5 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein PAGK PF15284.4 132529.4_18529001_1 - 0.13 12.0 0.5 0.36 10.7 0.5 1.7 1 0 0 1 1 1 0 Phage-encoded virulence factor RNase_H2_suC PF08615.9 132529.4_18529001_1 - 0.15 12.1 0.7 0.62 10.1 0.1 2.1 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF913 PF06025.10 132529.4_18529001_1 - 0.18 10.6 3.1 0.8 8.5 0.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SDA1 PF05285.10 132529.4_18529001_1 - 0.25 10.6 16.2 0.077 12.3 9.7 2.3 2 0 0 2 2 2 0 SDA1 PBP1_TM PF14812.4 132529.4_18529001_1 - 1.8 8.9 7.6 7.8 6.9 7.6 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tim54 PF11711.6 132529.4_18529001_1 - 2.8 6.5 5.4 5.9 5.4 3.6 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Myc_N PF01056.16 132529.4_18529001_1 - 5.1 6.7 12.4 1.6 8.4 4.3 2.2 2 0 0 2 2 2 0 Myc amino-terminal region Nop14 PF04147.10 132529.4_18529001_1 - 7.9 4.4 23.5 0.23 9.5 13.2 2.7 3 0 0 3 3 3 0 Nop14-like family SSP160 PF06933.9 132529.4_18529001_1 - 9.5 4.1 10.4 14 3.6 10.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Anoctamin PF04547.10 167312.4_18529001_1 - 5.3e-140 466.9 13.1 6.8e-140 466.6 13.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.3 167312.4_18529001_1 - 2.9e-52 177.5 0.8 4.3e-52 177.0 0.8 1.2 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.7 167312.4_18529001_1 - 0.92 8.1 3.0 2.1 6.9 3.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) INSC_LBD PF16748.3 167318.1_18524001_2 - 0.2 11.0 0.7 0.42 10.0 0.7 1.5 1 0 0 1 1 1 0 Inscuteable LGN-binding domain p450 PF00067.20 167318.1_18524001_3 - 1.4e-62 211.9 0.2 1.8e-62 211.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 HisKA_7TM PF16927.3 167318.1_18524001_3 - 0.065 13.1 0.6 0.11 12.4 0.6 1.3 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase Myb_DNA-binding PF00249.29 167335.2_18529001_3 - 0.0044 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2967 PF11179.6 132636.4_18525001_1 - 7.3 5.8 16.3 14 4.9 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) IPK PF03770.14 132647.2_18526001_1 - 3.1e-40 138.0 0.1 8.5e-40 136.6 0.1 1.8 1 1 0 1 1 1 1 Inositol polyphosphate kinase CDC45 PF02724.12 132647.2_18526001_1 - 0.27 9.4 4.3 0.41 8.8 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.10 132647.2_18526001_1 - 0.31 10.2 8.0 0.7 9.1 8.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PNISR PF15996.3 132647.2_18526001_1 - 0.63 10.1 4.4 1.9 8.5 4.4 1.8 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Nop14 PF04147.10 132647.2_18526001_1 - 2.4 6.1 8.2 3.7 5.5 8.2 1.2 1 0 0 1 1 1 0 Nop14-like family TANGO2 PF05742.10 132677.4_18523001_2 - 3.1e-63 214.0 0.0 3.7e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Peptidase_M14 PF00246.22 132686.3_18529001_3 - 8.9e-16 58.4 0.0 2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF4746 PF15928.3 132686.3_18529001_3 - 0.009 15.3 2.7 0.072 12.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) AstE_AspA PF04952.12 132686.3_18529001_3 - 0.096 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family LIM PF00412.20 132702.5_18526001_2 - 1.9e-34 117.5 37.6 4.4e-12 45.9 10.2 3.4 3 0 0 3 3 3 3 LIM domain A_deaminase PF00962.20 167385.4_18526001_3 - 1.1e-122 409.3 0.1 1.8e-122 408.6 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase PF00962.20 167386.2_18526001_1 - 9.2e-123 409.6 0.1 1.5e-122 408.9 0.1 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase BTB PF00651.29 167387.5_18529001_2 - 1.1e-22 80.2 0.4 2.6e-22 79.0 0.4 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.24 167387.5_18529001_2 - 2e-14 53.0 45.8 0.003 17.8 0.2 7.9 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 167387.5_18529001_2 - 2.9e-12 46.3 36.2 1.4e-07 31.5 2.4 6.7 6 0 0 6 6 6 2 Zinc-finger double domain ADK_lid PF05191.12 167387.5_18529001_2 - 1.3 8.9 5.0 0.78 9.7 0.2 2.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid CK_II_beta PF01214.16 206698.2_18522001_1 - 3.6e-47 160.4 0.0 4.3e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Zn_Tnp_IS1 PF03811.11 206698.2_18522001_1 - 0.0058 16.2 0.4 0.0058 16.2 0.4 2.1 3 0 0 3 3 3 1 InsA N-terminal domain NAC PF01849.16 132710.3_18523001_2 - 2.3e-11 43.4 0.1 2.3e-11 43.4 0.1 2.1 3 0 0 3 3 3 1 NAC domain HA2 PF04408.21 132719.3_18528001_3 - 2.3e-20 72.7 0.0 2.3e-20 72.7 0.0 4.0 5 0 0 5 5 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.14 132719.3_18528001_3 - 4.1e-17 62.2 0.0 1.3e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.29 132719.3_18528001_3 - 8.3e-14 51.8 0.0 2.6e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.4 132719.3_18528001_3 - 1.3e-06 28.6 0.0 6e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain DEAD PF00270.27 132719.3_18528001_3 - 1.6e-06 27.9 0.1 4.6e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.4 132719.3_18528001_3 - 0.00032 20.9 0.0 0.00097 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.7 132719.3_18528001_3 - 0.00077 18.7 2.2 0.0015 17.7 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.18 132719.3_18528001_3 - 0.0018 17.3 0.0 0.005 15.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.4 132719.3_18528001_3 - 0.0019 17.8 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Microtub_bd PF16796.3 132719.3_18528001_3 - 0.0056 16.5 0.5 0.025 14.4 0.2 2.3 3 0 0 3 3 2 1 Microtubule binding Flavi_DEAD PF07652.12 132719.3_18528001_3 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.20 132719.3_18528001_3 - 0.061 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.25 132719.3_18528001_3 - 0.077 13.4 0.0 0.29 11.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.4 132719.3_18528001_3 - 0.11 12.4 0.4 0.91 9.4 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.4 132719.3_18528001_3 - 0.11 12.5 0.0 0.11 12.5 0.0 2.8 2 1 0 2 2 1 0 AAA domain ATPase PF06745.11 132719.3_18528001_3 - 0.12 11.6 0.6 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 KaiC cobW PF02492.17 132719.3_18528001_3 - 0.15 11.5 1.1 0.72 9.3 0.1 2.5 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF883 PF05957.11 132719.3_18528001_3 - 7 7.2 13.7 3.9 8.0 2.8 3.1 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF883) I-set PF07679.14 167408.2_18529001_2 - 7.6e-18 64.2 0.0 1.3e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.23 167408.2_18529001_2 - 1.7e-17 63.2 0.2 2.8e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 167408.2_18529001_2 - 1.5e-16 60.6 0.3 2.4e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 167408.2_18529001_2 - 8.6e-14 51.5 0.1 5.5e-10 39.2 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.4 167408.2_18529001_2 - 1.9e-10 40.8 0.2 2.4e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Band_7 PF01145.23 167419.2_18526001_2 - 9.3e-13 48.4 0.1 9.3e-13 48.4 0.1 2.2 2 0 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.3 167419.2_18526001_2 - 1.4e-06 28.3 6.3 1.4e-06 28.3 6.3 3.2 2 2 1 3 3 3 1 Flotillin Band_7_1 PF13421.4 167419.2_18526001_2 - 0.067 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family CDP-OH_P_transf PF01066.19 132827.3_18523001_3 - 3.6e-13 50.0 1.2 3.6e-13 50.0 1.2 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Fer4_20 PF14691.4 078613.4_18525001_1 - 0.014 15.0 0.7 0.024 14.3 0.7 1.3 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster BRO1 PF03097.16 078613.4_18525001_3 - 2.6e-76 256.8 0.5 3.8e-76 256.3 0.5 1.2 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.14 078613.4_18525001_3 - 1.8e-18 66.3 4.6 1.8e-18 66.3 4.6 2.4 2 0 0 2 2 2 1 Hr1 repeat PDZ PF00595.22 078613.4_18525001_3 - 8e-10 38.8 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Peroxin-13_N PF04088.11 078613.4_18525001_3 - 0.045 13.9 0.4 0.14 12.3 0.4 1.8 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DALR_1 PF05746.13 078613.4_18525001_3 - 0.18 11.8 2.0 0.5 10.4 0.4 2.4 1 1 1 2 2 2 0 DALR anticodon binding domain Com_YlbF PF06133.9 078613.4_18525001_3 - 3.6 8.1 10.1 1.6 9.2 3.9 2.9 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA zf-C3HC4_3 PF13920.4 001103518.3_18523001_2 - 4e-10 39.3 5.4 7e-10 38.5 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001103518.3_18523001_2 - 2.1e-09 37.0 7.2 4.1e-09 36.0 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001103518.3_18523001_2 - 2.8e-09 36.9 9.3 5.1e-09 36.1 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.4 001103518.3_18523001_2 - 2.5e-08 33.5 9.3 5.2e-08 32.5 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001103518.3_18523001_2 - 3.6e-07 29.8 6.4 6.2e-07 29.0 6.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 001103518.3_18523001_2 - 2.8e-06 27.1 3.6 2.8e-06 27.1 3.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 001103518.3_18523001_2 - 6.7e-06 25.8 6.0 1.2e-05 25.1 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.9 001103518.3_18523001_2 - 0.0002 21.2 2.2 0.00034 20.4 2.2 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.5 001103518.3_18523001_2 - 0.00026 21.1 7.1 0.00052 20.1 7.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.4 001103518.3_18523001_2 - 0.001 19.0 7.1 0.0019 18.2 7.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.5 001103518.3_18523001_2 - 0.0012 18.8 2.3 0.002 18.0 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.10 001103518.3_18523001_2 - 0.0084 15.4 0.4 0.014 14.7 0.4 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Di19 PF05605.10 001103518.3_18523001_2 - 0.0093 16.1 1.1 4.1 7.6 0.2 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.19 001103518.3_18523001_2 - 0.16 12.1 7.4 0.5 10.5 3.3 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.4 001103518.3_18523001_2 - 0.29 10.8 5.8 0.75 9.4 5.8 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.3 001103518.3_18523001_2 - 2.3 7.9 8.0 0.31 10.7 3.7 1.9 2 0 0 2 2 2 0 RING-like zinc finger CPSase_L_D2 PF02786.15 206765.3_18529001_1 - 2.8e-106 353.6 0.0 3.7e-80 268.3 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.20 206765.3_18529001_1 - 1.1e-45 154.5 0.0 2.2e-45 153.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.26 206765.3_18529001_1 - 1.9e-43 148.3 0.0 1.1e-42 145.9 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.19 206765.3_18529001_1 - 3.3e-42 143.8 0.0 6.4e-42 142.8 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.17 206765.3_18529001_1 - 7.4e-39 132.7 0.0 1.7e-38 131.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.22 206765.3_18529001_1 - 2.6e-33 115.2 0.0 5.8e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.20 206765.3_18529001_1 - 5.2e-19 68.1 0.0 2.8e-18 65.8 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.20 206765.3_18529001_1 - 4.4e-17 62.0 0.1 6.8e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.11 206765.3_18529001_1 - 3.3e-15 56.0 0.1 9.2e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.4 206765.3_18529001_1 - 2.9e-13 49.1 0.0 0.00018 20.2 0.0 3.9 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Amidohydro_1 PF01979.18 206765.3_18529001_1 - 2.9e-11 43.1 0.4 4.1e-09 36.1 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family ATP-grasp_3 PF02655.12 206765.3_18529001_1 - 2e-06 27.8 0.1 0.0042 17.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.11 206765.3_18529001_1 - 1.3e-05 24.9 2.4 0.00025 20.8 0.3 2.8 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.22 206765.3_18529001_1 - 0.00015 21.5 0.0 0.0022 17.7 0.0 2.6 2 0 0 2 2 2 1 DJ-1/PfpI family GARS_A PF01071.17 206765.3_18529001_1 - 0.05 13.2 0.0 0.19 11.3 0.0 2.0 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SUI1 PF01253.20 132948.4_18522001_2 - 5.2e-19 68.4 0.0 9.4e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Aa_trans PF01490.16 132964.3_18524001_1 - 3.2e-62 210.4 27.0 4e-62 210.1 27.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phostensin_N PF13916.4 176747.1_18524001_3 - 1.9 8.8 13.3 2.3 8.5 5.1 2.7 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal SMN PF06003.10 176747.1_18524001_3 - 9.5 5.3 12.7 18 4.4 12.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RasGAP PF00616.17 133012.5_18529001_1 - 1e-22 80.7 0.1 3.2e-15 56.2 0.0 5.4 5 2 1 6 6 6 3 GTPase-activator protein for Ras-like GTPase DUF3498 PF12004.6 133012.5_18529001_1 - 7.6e-16 58.3 5.0 7.6e-16 58.3 5.0 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF3498) C2 PF00168.28 133012.5_18529001_1 - 1.1e-10 41.6 0.1 2.3e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 C2 domain PH PF00169.27 133012.5_18529001_1 - 0.0039 17.5 0.0 0.026 14.9 0.0 2.5 2 0 0 2 2 2 1 PH domain Homeobox PF00046.27 078665.3_18523001_1 - 4.1e-22 77.6 1.4 9.2e-22 76.5 1.4 1.6 1 0 0 1 1 1 1 Homeobox domain MarR_2 PF12802.5 078665.3_18523001_1 - 0.024 14.4 1.1 0.89 9.4 0.0 2.5 2 0 0 2 2 2 0 MarR family Fibrinogen_C PF00147.16 133026.1_18523001_1 - 2.3e-50 171.3 6.5 3.3e-50 170.8 6.5 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain IncA PF04156.12 133026.1_18523001_1 - 0.018 14.7 1.6 0.024 14.3 1.6 1.2 1 0 0 1 1 1 0 IncA protein Ion_trans PF00520.29 078669.5_18529001_3 - 3.2e-49 167.2 11.6 6.1e-49 166.3 11.6 1.5 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 078669.5_18529001_3 - 4.1e-27 94.2 0.0 7.8e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 078669.5_18529001_3 - 3.4e-12 46.0 8.2 3.4e-12 46.0 8.2 2.5 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.29 001272737.1_18528001_2 - 1.4e-49 168.4 11.6 2.1e-49 167.8 11.6 1.3 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001272737.1_18528001_2 - 1.8e-27 95.3 0.0 3.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001272737.1_18528001_2 - 1.5e-12 47.2 8.2 1.5e-12 47.2 8.2 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.10 001272737.1_18528001_2 - 0.016 13.8 4.8 0.031 12.8 4.8 1.4 1 0 0 1 1 1 0 Polycystin cation channel RhoGAP PF00620.25 176755.3_18526001_3 - 2.9e-26 92.0 0.0 9.3e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain PI3K_P85_iSH2 PF16454.3 176755.3_18526001_3 - 0.001 18.5 0.4 0.0019 17.7 0.4 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain 5_nucleotid PF05761.12 133061.3_18525001_1 - 1.1e-178 594.7 0.6 1.4e-178 594.4 0.6 1.0 1 0 0 1 1 1 1 5' nucleotidase family LRR_6 PF13516.4 133063.2_18523001_3 - 0.00012 21.7 8.0 0.17 11.9 0.2 4.7 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.5 133063.2_18523001_3 - 0.00024 21.3 13.7 0.011 16.0 0.8 5.1 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 133063.2_18523001_3 - 0.35 10.6 8.3 0.62 9.7 0.7 3.8 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.31 133063.2_18523001_3 - 1 9.9 13.2 22 5.9 0.1 5.9 4 1 0 4 4 4 0 Leucine Rich Repeat RGS PF00615.17 133100.4_18529001_3 - 7.2e-32 110.0 0.0 1.4e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.19 133100.4_18529001_3 - 3.9e-15 55.5 0.0 7.5e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.20 133100.4_18529001_3 - 8.6e-15 54.4 0.1 1.8e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 GGL domain Tudor-knot PF11717.6 133104.3_18529001_3 - 1.7e-14 53.3 0.4 4.2e-14 52.0 0.4 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.22 133104.3_18529001_3 - 0.017 14.8 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RBB1NT PF08169.9 133102.3_18529001_1 - 7.6e-31 106.1 1.2 2e-30 104.8 1.2 1.8 1 0 0 1 1 1 1 RBB1NT (NUC162) domain ARID PF01388.19 133102.3_18529001_1 - 1.7e-22 79.7 0.1 3.7e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.6 133102.3_18529001_1 - 1.6e-14 53.4 0.4 5.9e-14 51.6 0.4 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.22 133102.3_18529001_1 - 0.023 14.4 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.15 133102.3_18529001_1 - 0.17 12.2 8.3 0.25 11.7 0.1 3.4 3 0 0 3 3 3 0 PWWP domain OB_NTP_bind PF07717.14 167649.2_18528001_2 - 8.8e-21 74.0 0.0 2.6e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.21 167649.2_18528001_2 - 3.8e-14 52.7 0.8 1.6e-13 50.7 0.8 2.2 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.29 167649.2_18528001_2 - 2.5e-12 47.0 1.1 6.3e-12 45.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.27 167649.2_18528001_2 - 1.4e-05 24.8 0.1 8.7e-05 22.2 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.18 167649.2_18528001_2 - 0.024 13.6 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.4 167649.2_18528001_2 - 0.064 13.4 1.0 0.3 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.4 167649.2_18528001_2 - 0.22 11.7 6.4 0.35 11.1 0.1 3.2 2 1 0 2 2 2 0 AAA ATPase domain SR-25 PF10500.7 167649.2_18528001_2 - 0.23 10.9 11.2 1.4 8.3 6.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Kri1 PF05178.10 167649.2_18528001_2 - 0.47 10.9 3.7 2 8.9 3.7 2.1 1 0 0 1 1 1 0 KRI1-like family zf-TAZ PF02135.14 167649.2_18528001_2 - 0.77 10.1 3.4 2.4 8.6 3.4 1.8 1 0 0 1 1 1 0 TAZ zinc finger COX6B PF02297.15 167678.3_18522001_2 - 4.7e-17 61.9 6.4 8.4e-17 61.0 6.4 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.11 167678.3_18522001_2 - 0.41 10.7 3.1 0.77 9.8 3.1 1.5 1 0 0 1 1 1 0 CHCH domain TAFA PF12020.6 167678.3_18522001_3 - 0.061 13.6 0.8 0.061 13.6 0.8 2.0 2 1 0 2 2 2 0 TAFA family CH PF00307.29 134508.3_18524001_2 - 3.6e-37 126.8 1.2 6.1e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.6 134508.3_18524001_2 - 3.6e-05 23.4 0.1 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.9 134508.3_18524001_2 - 0.019 14.9 0.0 0.28 11.2 0.0 2.4 2 0 0 2 2 2 0 CH-like domain in sperm protein Asp2 PF16929.3 134508.3_18524001_2 - 0.1 11.5 0.4 0.22 10.4 0.0 1.6 2 0 0 2 2 2 0 Accessory Sec system GspB-transporter Dynein_IC2 PF11540.6 057727.5_18526001_2 - 5.3e-13 48.5 5.6 5.3e-13 48.5 5.6 2.6 2 0 0 2 2 2 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.30 057727.5_18526001_2 - 1.2e-06 28.9 6.6 1.3 9.9 0.1 7.0 7 0 0 7 7 7 2 WD domain, G-beta repeat Frtz PF11768.6 057727.5_18526001_2 - 0.075 11.2 0.1 3.1 5.9 0.1 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.5 057727.5_18526001_2 - 0.086 13.0 0.0 38 4.5 0.0 3.5 3 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PBP_GOBP PF01395.20 167701.2_18522001_2 - 6.6e-15 55.1 1.9 9.3e-15 54.7 1.9 1.2 1 0 0 1 1 1 1 PBP/GOBP family Tektin PF03148.12 167762.4_18524001_2 - 8e-130 432.9 21.9 9.3e-130 432.7 21.9 1.0 1 0 0 1 1 1 1 Tektin family Baculo_PEP_C PF04513.10 167762.4_18524001_2 - 0.58 10.1 3.7 2.7 7.9 0.4 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.10 167762.4_18524001_2 - 1.2 9.0 11.9 0.59 10.0 4.4 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) UCH PF00443.27 134618.3_18527001_3 - 5.8e-65 219.2 2.3 8e-65 218.7 2.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 134618.3_18527001_3 - 1.2e-22 80.8 3.2 1.9e-22 80.1 3.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CAP_N PF01213.17 134618.3_18527001_3 - 1.2 8.4 9.8 2.2 7.6 9.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.3 134618.3_18527001_3 - 2.2 8.2 10.7 6.7 6.6 10.7 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PP2C PF00481.19 134624.4_18526001_2 - 3.3e-26 92.4 0.2 6.8e-12 45.4 0.0 3.7 4 0 0 4 4 4 3 Protein phosphatase 2C SpoIIE PF07228.10 134624.4_18526001_2 - 0.0057 16.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Coilin_N PF15862.3 134624.4_18526001_2 - 0.77 9.4 9.4 1.4 8.5 9.4 1.5 1 0 0 1 1 1 0 Coilin N-terminus DUF2967 PF11179.6 134624.4_18526001_2 - 2.6 7.3 13.7 5 6.4 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) CBM_14 PF01607.22 167788.2_18524001_3 - 3.8e-12 46.1 7.2 3.8e-12 46.1 7.2 2.8 3 0 0 3 3 3 1 Chitin binding Peritrophin-A domain zf-H2C2_2 PF13465.4 001272459.1_18528001_2 - 3.5e-13 49.2 7.9 2.2e-08 34.0 1.1 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.24 001272459.1_18528001_2 - 4.2e-08 33.1 19.9 1.6e-05 25.0 1.0 4.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001272459.1_18528001_2 - 2.5e-05 24.6 8.6 0.00042 20.8 1.5 5.2 4 0 0 4 4 4 3 C2H2-type zinc finger EPL1 PF10513.7 001272459.1_18528001_2 - 0.00064 20.0 8.3 0.0017 18.6 8.3 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like TFIIA PF03153.11 001272459.1_18528001_2 - 0.12 12.2 49.6 0.012 15.6 38.2 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.4 001272459.1_18528001_2 - 0.15 12.1 7.8 0.37 10.8 7.8 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EOS1 PF12326.6 001272459.1_18528001_2 - 0.93 9.3 5.1 2.1 8.1 5.1 1.5 1 0 0 1 1 1 0 N-glycosylation protein Tim54 PF11711.6 001272459.1_18528001_2 - 1.1 7.8 13.7 1.8 7.1 13.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pex14_N PF04695.11 001272459.1_18528001_2 - 5.2 7.6 30.1 0.23 12.0 21.6 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.14 001272459.1_18528001_2 - 6.9 6.5 18.2 1.1 9.1 13.8 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Carb_anhydrase PF00194.19 001298057.1_18528001_2 - 5e-73 245.6 0.1 6.6e-73 245.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Bystin PF05291.9 078519.3_18524001_2 - 4.3e-135 449.5 0.5 6e-135 449.1 0.5 1.1 1 0 0 1 1 1 1 Bystin zf-HIT PF04438.14 001298231.1_18523001_3 - 1.2e-07 31.3 11.0 2.6e-07 30.2 11.0 1.6 1 0 0 1 1 1 1 HIT zinc finger LIAS_N PF16881.3 132501.3_18523001_3 - 0.08 13.2 0.3 0.2 12.0 0.1 1.7 1 1 1 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family EcKinase PF02958.18 206689.2_18525001_1 - 3.1e-73 246.5 0.0 4.9e-73 245.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.9 206689.2_18525001_1 - 1.3e-18 66.9 0.0 2.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.21 206689.2_18525001_1 - 5e-11 42.8 0.6 5e-11 42.8 0.6 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.18 206689.2_18525001_1 - 0.00032 20.2 0.0 0.00059 19.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase AhpC-TSA PF00578.19 001298275.1_18522001_2 - 1.5e-36 124.9 0.0 2.2e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001298275.1_18522001_2 - 6.8e-15 54.9 0.0 9.7e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 001298275.1_18522001_2 - 4.7e-14 51.8 0.1 8.1e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Metallophos PF00149.26 001298166.1_18525001_3 - 1.9e-25 90.5 0.3 3.1e-25 89.8 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.4 001298166.1_18525001_3 - 2.1e-24 86.0 0.3 8.8e-24 84.0 0.1 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.3 001298166.1_18525001_3 - 1.5e-18 67.0 0.0 3.1e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.5 001298166.1_18525001_3 - 0.00038 20.6 0.0 0.00068 19.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_1_2 PF00155.19 001298277.1_18525001_2 - 1.7e-35 122.7 0.0 2.8e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001298277.1_18525001_2 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase KH_1 PF00013.27 167251.3_18529001_3 - 3.7e-58 193.1 12.6 9.4e-14 50.9 0.7 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.15 167251.3_18529001_3 - 2.5e-15 55.9 7.7 5.3e-05 22.8 0.1 4.5 4 0 0 4 4 4 3 KH domain KH_4 PF13083.4 167251.3_18529001_3 - 1.9e-14 53.1 1.6 0.002 17.8 0.1 4.5 4 0 0 4 4 4 4 KH domain MOEP19 PF16005.3 167251.3_18529001_3 - 9.4e-09 35.1 0.0 0.0036 17.1 0.0 4.0 4 0 0 4 4 4 2 KH-like RNA-binding domain KH_5 PF13184.4 167251.3_18529001_3 - 1.7e-08 34.3 8.2 0.13 12.2 0.1 4.5 4 0 0 4 4 4 4 NusA-like KH domain Tweety PF04906.11 001272840.2_18529001_2 - 3.8e-155 516.4 4.2 3.8e-155 516.4 4.2 1.8 2 0 0 2 2 2 1 Tweety RR_TM4-6 PF06459.10 001272840.2_18529001_2 - 4.6 6.9 22.0 0.092 12.4 9.0 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 GST_C PF00043.23 001169337.2_18522001_2 - 2e-10 40.6 0.0 4.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001169337.2_18522001_2 - 2.8e-10 39.9 0.0 5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001169337.2_18522001_2 - 2.1e-08 34.3 0.0 3.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001169337.2_18522001_2 - 5.5e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001169337.2_18522001_2 - 0.00012 22.2 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001169337.2_18522001_2 - 0.002 18.3 0.0 0.0039 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Guanylate_kin PF00625.19 206681.4_18529001_1 - 4.3e-69 231.7 0.1 9.3e-69 230.6 0.1 1.6 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.22 206681.4_18529001_1 - 3.3e-61 203.5 14.1 2.3e-20 72.6 0.2 3.6 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) L27_1 PF09058.8 206681.4_18529001_1 - 2.3e-28 97.9 3.8 5.6e-28 96.7 3.8 1.7 1 0 0 1 1 1 1 L27_1 PDZ_2 PF13180.4 206681.4_18529001_1 - 1.8e-11 44.1 5.0 1.5e-05 25.1 0.4 3.6 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.26 206681.4_18529001_1 - 3.4e-09 36.0 0.1 8.4e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 206681.4_18529001_1 - 1.2e-08 34.3 0.0 2.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 206681.4_18529001_1 - 0.00058 19.5 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Intein_splicing PF14890.4 206681.4_18529001_1 - 0.0093 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Intein splicing domain Guanylate_kin PF00625.19 001103485.3_18529001_2 - 6.4e-69 231.2 0.1 1.3e-68 230.2 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.22 001103485.3_18529001_2 - 8.4e-61 202.2 14.1 3.1e-20 72.2 0.2 3.6 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001103485.3_18529001_2 - 3.4e-11 43.2 5.0 2e-05 24.7 0.4 3.8 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.26 001103485.3_18529001_2 - 4.9e-09 35.5 0.1 1.1e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001103485.3_18529001_2 - 1.8e-08 33.8 0.0 3.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 001103485.3_18529001_2 - 0.00077 19.1 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Intein_splicing PF14890.4 001103485.3_18529001_2 - 0.012 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Intein splicing domain Guanylate_kin PF00625.19 001272517.1_18529001_3 - 4.8e-69 231.6 0.1 8.7e-69 230.7 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.22 001272517.1_18529001_3 - 2.2e-61 204.0 14.1 2.2e-20 72.7 0.2 3.8 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001272517.1_18529001_3 - 1.3e-11 44.5 5.0 1.4e-05 25.2 0.4 3.7 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.26 001272517.1_18529001_3 - 3.2e-09 36.1 0.1 7.9e-09 34.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001272517.1_18529001_3 - 1.2e-08 34.4 0.0 2.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 001272517.1_18529001_3 - 0.00055 19.6 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Intein_splicing PF14890.4 001272517.1_18529001_3 - 0.0088 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Intein splicing domain Mit_proteolip PF08039.9 001272517.1_18529001_3 - 2.6 8.3 8.3 5.3 7.3 8.3 1.5 1 0 0 1 1 1 0 Mitochondrial proteolipid DUF4611 PF15387.4 132483.3_18529001_3 - 0.21 11.7 5.2 0.33 11.1 3.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AT_hook PF02178.17 132483.3_18529001_3 - 3.1 7.9 12.2 1.1 9.3 7.3 2.9 2 0 0 2 2 2 0 AT hook motif SPC25 PF06703.9 001298195.1_18522001_3 - 1.8e-39 135.0 0.0 2.4e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Integrin_alpha2 PF08441.10 001272576.2_18529001_2 - 6.7e-144 480.1 1.1 8.5e-144 479.8 1.1 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 001272576.2_18529001_2 - 8.5e-18 64.0 13.0 3.6e-10 39.6 0.1 4.3 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.4 001272576.2_18529001_2 - 7.4e-07 29.5 2.3 9.3e-05 22.8 0.0 4.0 2 1 2 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001272576.2_18529001_2 - 0.0013 18.5 0.0 0.0037 17.0 0.0 1.9 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region PliI PF16743.3 001272576.2_18529001_2 - 0.11 12.2 0.0 1 9.0 0.0 2.2 1 1 1 2 2 2 0 Periplasmic lysozyme inhibitor of I-type lysozyme ER PF01133.15 001272435.1_18523001_1 - 3.5e-44 148.7 0.2 6.1e-44 147.9 0.2 1.4 1 0 0 1 1 1 1 Enhancer of rudimentary Ras PF00071.20 167323.2_18524001_2 - 1.8e-34 118.6 0.0 3.6e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.11 167323.2_18524001_2 - 1.3e-19 70.5 0.0 2.4e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.14 167323.2_18524001_2 - 5.4e-07 29.7 0.4 1.2e-06 28.6 0.4 1.7 1 0 0 1 1 1 1 SOCS box Arf PF00025.19 167323.2_18524001_2 - 0.00014 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MS_channel PF00924.16 132158.2_18522001_3 - 0.13 11.6 0.8 0.22 10.9 0.1 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel GNAT_acetyltr_2 PF13718.4 001298096.1_18527001_2 - 3.2e-94 314.4 0.0 6.2e-94 313.5 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.4 001298096.1_18527001_2 - 4.8e-65 219.4 3.3 7.6e-65 218.8 3.3 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.12 001298096.1_18527001_2 - 1.6e-61 207.1 0.1 6.8e-61 205.1 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.9 001298096.1_18527001_2 - 2.9e-33 113.5 0.2 9.1e-33 111.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.5 001298096.1_18527001_2 - 0.0053 17.0 0.0 0.021 15.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.23 001298096.1_18527001_2 - 0.02 15.0 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Trypsin PF00089.24 001272413.1_18524001_1 - 4.8e-57 193.2 0.0 6.1e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001272413.1_18524001_1 - 1.9e-07 32.0 0.0 3.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Abhydrolase_1 PF00561.18 132160.3_18523001_2 - 6.8e-22 78.2 0.0 3e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 132160.3_18523001_2 - 1.2e-14 55.4 0.0 1.8e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 132160.3_18523001_2 - 2.2e-10 40.1 0.0 5.1e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2048 PF09752.7 132160.3_18523001_2 - 2.4e-05 23.5 0.0 4.1e-05 22.7 0.0 1.4 2 0 0 2 2 2 1 Abhydrolase domain containing 18 PGAP1 PF07819.11 132160.3_18523001_2 - 0.00081 19.0 0.0 0.014 15.0 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.18 132160.3_18523001_2 - 0.0042 17.1 0.0 0.019 15.0 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.12 132160.3_18523001_2 - 0.0056 15.3 0.0 0.011 14.3 0.0 1.6 1 1 0 1 1 1 1 Ndr family Esterase PF00756.18 132160.3_18523001_2 - 0.0059 16.1 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Bax1-I PF01027.18 132453.2_18523001_3 - 1.5e-42 145.6 10.4 2.3e-42 145.1 10.4 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 GETHR PF05671.9 132432.1_18529001_1 - 0.17 11.2 3.6 0.59 9.4 3.6 1.9 1 0 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) F-box PF00646.31 001258697.2_18527001_2 - 9e-05 22.1 0.2 0.00022 20.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001258697.2_18527001_2 - 0.00024 20.8 0.4 0.00065 19.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.5 001258697.2_18527001_2 - 0.1 12.9 7.8 5 7.5 0.1 4.2 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Cript PF10235.7 001258697.2_18527001_2 - 1.1 9.8 7.4 0.13 12.8 1.7 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT PT PF04886.10 167144.4_18529001_1 - 0.0046 16.3 13.7 0.0088 15.4 13.7 1.4 1 0 0 1 1 1 1 PT repeat Bromodomain PF00439.23 167144.4_18529001_2 - 3.3e-41 139.1 2.3 1.5e-19 69.7 0.6 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.3 167144.4_18529001_2 - 1.1e-28 99.1 0.1 3.7e-28 97.3 0.1 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation PT PF04886.10 167144.4_18529001_2 - 0.025 14.0 14.9 0.098 12.1 14.9 2.1 1 0 0 1 1 1 0 PT repeat TT_ORF2 PF02957.13 167299.2_18528001_1 - 0.00093 20.0 17.2 0.042 14.6 9.9 3.2 2 0 0 2 2 2 2 TT viral ORF2 Rod_cone_degen PF15201.4 167299.2_18528001_1 - 0.12 12.4 0.0 0.62 10.1 0.0 2.3 1 0 0 1 1 1 0 Progressive rod-cone degeneration PRIMA1 PF16101.3 167299.2_18528001_1 - 4.1 7.3 6.1 13 5.8 6.1 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.17 132540.3_18527001_2 - 0.37 10.1 5.5 1.3 8.3 0.4 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mur_ligase_M PF08245.10 001298232.1_18524001_2 - 0.00011 22.1 0.0 0.00047 20.1 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain DUF257 PF03192.11 001298232.1_18524001_2 - 0.097 12.1 0.1 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 Myb_DNA-binding PF00249.29 057757.4_18528001_2 - 0.00029 20.8 0.0 0.00076 19.4 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 057757.4_18528001_2 - 0.00052 19.7 0.1 0.0012 18.5 0.1 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.4 057757.4_18528001_2 - 0.88 9.7 3.8 3.6 7.8 0.5 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain RBD PF02196.13 080022.4_18529001_3 - 0.53 10.3 2.7 2.3 8.2 0.0 3.1 3 0 0 3 3 3 0 Raf-like Ras-binding domain Ras PF00071.20 166985.3_18525001_1 - 6.3e-54 181.8 0.1 9.3e-54 181.3 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 166985.3_18525001_1 - 5.5e-20 71.7 0.3 1.2e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 166985.3_18525001_1 - 3.9e-10 39.3 0.0 6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 166985.3_18525001_1 - 3.3e-05 23.7 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 166985.3_18525001_1 - 6.3e-05 22.5 0.0 0.00022 20.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 166985.3_18525001_1 - 0.0083 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SHMT PF00464.17 001297987.1_18524001_2 - 4.5e-195 647.8 0.0 5.3e-195 647.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.15 001297987.1_18524001_2 - 0.0065 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family UCH PF00443.27 132046.3_18525001_3 - 2.3e-31 109.1 0.0 3.1e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 132046.3_18525001_3 - 1.1e-16 61.2 0.0 1e-12 48.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MOZ_SAS PF01853.16 078496.3_18527001_3 - 8.1e-82 273.1 0.5 1.5e-81 272.2 0.5 1.4 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.6 078496.3_18527001_3 - 3.5e-18 65.1 1.2 3.2e-17 62.1 0.1 2.4 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.23 078496.3_18527001_3 - 0.00095 19.2 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.5 078496.3_18527001_3 - 0.0025 18.1 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Innexin PF00876.16 001258628.3_18525001_2 - 2.6e-84 283.4 12.8 3.5e-84 283.0 12.8 1.2 1 0 0 1 1 1 1 Innexin Nrf1_DNA-bind PF10491.7 001272163.1_18529001_1 - 4.9e-110 366.1 0.0 7.9e-110 365.4 0.0 1.3 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.7 001272163.1_18529001_1 - 5.2e-14 52.5 2.7 5.2e-14 52.5 2.7 5.6 3 1 3 6 6 6 1 Nrf1 activator activation site binding domain Nrf1_DNA-bind PF10491.7 001272164.1_18528001_1 - 4.9e-110 366.1 0.0 7.6e-110 365.5 0.0 1.3 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.7 001272164.1_18528001_1 - 5e-14 52.6 2.7 5e-14 52.6 2.7 5.1 3 1 2 5 5 5 1 Nrf1 activator activation site binding domain 7tm_1 PF00001.19 001297972.1_18524001_2 - 5.8e-41 140.4 14.1 8.8e-41 139.8 14.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sigma_reg_N PF13800.4 001297972.1_18524001_2 - 0.083 13.1 0.2 0.083 13.1 0.2 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal 7TM_GPCR_Srx PF10328.7 001297972.1_18524001_2 - 2.1 7.5 27.2 0.007 15.6 13.3 2.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx RRM_1 PF00076.20 001103414.3_18527001_2 - 5.1e-19 67.7 0.0 1.4e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.9 001103414.3_18527001_2 - 9.8e-09 34.3 0.7 2.3e-08 33.1 0.7 1.7 1 0 0 1 1 1 1 Lsm interaction motif 6PF2K PF01591.16 167654.2_18526001_2 - 2.7e-86 288.4 0.3 4.4e-86 287.7 0.3 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.20 167654.2_18526001_2 - 2.3e-40 138.2 0.2 9e-40 136.3 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.4 167654.2_18526001_2 - 2.2e-07 31.0 0.0 4.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.8 167654.2_18526001_2 - 0.069 12.4 0.3 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 GRIM-19 PF06212.10 001298014.1_18522001_1 - 4.5e-55 185.1 0.0 5.7e-55 184.7 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein ANAPC_CDC26 PF10471.7 130629.3_18522001_3 - 1.6e-06 28.8 0.1 1.6e-06 28.8 0.1 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 Serglycin PF04360.10 130629.3_18522001_3 - 0.13 12.0 14.4 0.29 10.9 14.2 1.6 1 1 0 1 1 1 0 Serglycin Tubulin PF00091.23 130629.3_18522001_3 - 0.4 10.7 5.0 0.69 9.9 5.0 1.3 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain AF-4 PF05110.11 130629.3_18522001_3 - 9.3 4.1 9.6 14 3.5 9.6 1.3 1 1 0 1 1 1 0 AF-4 proto-oncoprotein Choline_kinase PF01633.18 001258778.2_18525001_2 - 2.5e-59 200.3 0.3 6e-59 199.1 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.21 001258778.2_18525001_2 - 2.1e-09 37.6 0.0 3.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ndc1_Nup PF09531.8 131944.2_18525001_2 - 1.8 7.0 8.1 2.5 6.5 8.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup T-box PF00907.20 001258598.3_18529001_3 - 1.5e-83 279.4 0.9 1.5e-83 279.4 0.9 2.6 2 0 0 2 2 2 1 T-box Optomotor-blind PF11078.6 001258598.3_18529001_3 - 6.6e-31 106.5 22.1 6.6e-31 106.5 22.1 8.5 6 3 2 8 8 8 1 Optomotor-blind protein N-terminal region TFIIA PF03153.11 001258598.3_18529001_3 - 0.81 9.5 41.7 0.21 11.4 11.6 2.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EF-hand_6 PF13405.4 001298000.1_18523001_2 - 1.9e-08 33.4 6.3 3.8e-06 26.3 0.4 3.5 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.4 001298000.1_18523001_2 - 5.9e-08 32.9 3.5 2.4e-05 24.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001298000.1_18523001_2 - 4.4e-06 25.7 0.9 4.4e-06 25.7 0.9 3.3 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.4 001298000.1_18523001_2 - 0.00042 19.6 0.7 0.001 18.3 0.7 1.7 1 0 0 1 1 1 1 EF hand Herpes_UL32 PF06070.9 001298000.1_18523001_2 - 0.025 12.2 0.2 0.033 11.8 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 EF-hand_9 PF14658.4 001298000.1_18523001_2 - 0.037 14.2 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.4 001298000.1_18523001_2 - 0.23 11.1 4.7 1.1 8.9 0.3 2.9 2 1 1 3 3 3 0 EF-hand domain pair Ig_3 PF13927.4 167004.2_18526001_1 - 4.4e-57 190.5 6.4 1.9e-13 50.7 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.14 167004.2_18526001_1 - 4.1e-53 177.3 0.1 1.8e-15 56.6 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.4 167004.2_18526001_1 - 3.8e-38 129.6 2.6 1.1e-09 38.4 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.23 167004.2_18526001_1 - 4.6e-32 109.9 0.0 5.1e-07 29.6 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.15 167004.2_18526001_1 - 2.9e-18 65.9 1.0 0.0022 18.0 0.1 5.9 4 2 1 5 5 5 4 Immunoglobulin V-set domain fn3 PF00041.19 167004.2_18526001_1 - 2.9e-18 65.9 6.1 4.7e-10 39.6 0.1 3.2 4 0 0 4 4 4 2 Fibronectin type III domain C2-set_2 PF08205.10 167004.2_18526001_1 - 1.2e-15 57.2 1.4 9.5e-07 28.7 0.0 5.0 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.6 167004.2_18526001_1 - 0.053 13.6 0.0 2.5 8.2 0.0 2.9 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 V-set_CD47 PF08204.9 167004.2_18526001_1 - 0.67 9.8 4.7 28 4.6 0.0 4.1 3 2 1 4 4 4 0 CD47 immunoglobulin-like domain MFS_1 PF07690.14 001297835.1_18526001_1 - 8.9e-23 80.6 54.8 1.1e-22 80.3 6.7 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 001297835.1_18526001_1 - 1.2e-15 57.2 6.7 1.2e-15 57.2 6.7 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Trypsin PF00089.24 001297861.1_18523001_2 - 4.8e-46 157.2 0.0 6.3e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001297861.1_18523001_2 - 0.0025 18.6 0.0 0.0047 17.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain FAD-oxidase_C PF02913.17 166930.2_18524001_3 - 8.3e-62 208.9 0.0 1.8e-61 207.8 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.21 166930.2_18524001_3 - 7e-36 122.9 3.4 1.2e-35 122.1 3.4 1.4 1 0 0 1 1 1 1 FAD binding domain DUF601 PF04642.10 166930.2_18524001_3 - 0.058 12.8 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 zf-C2H2 PF00096.24 132089.4_18525001_1 - 8.4e-10 38.4 33.1 0.0016 18.7 1.0 6.3 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 132089.4_18525001_1 - 3e-09 36.8 37.4 0.005 17.4 1.2 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 132089.4_18525001_1 - 1.9e-05 24.7 33.7 0.0034 17.6 2.0 7.0 6 1 0 6 6 6 2 Zinc-finger double domain zf-C2H2_11 PF16622.3 132089.4_18525001_1 - 2.6e-05 23.7 22.4 0.00046 19.7 0.4 5.7 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2HE PF16278.3 132089.4_18525001_1 - 0.0032 17.7 20.5 0.25 11.7 0.3 5.5 2 1 3 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.5 132089.4_18525001_1 - 0.013 15.8 0.4 0.013 15.8 0.4 5.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 132089.4_18525001_1 - 0.016 15.0 0.6 0.016 15.0 0.6 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger DUF1610 PF07754.9 132089.4_18525001_1 - 0.065 13.1 2.4 0.18 11.7 2.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-C2H2_2 PF12756.5 132089.4_18525001_1 - 0.2 11.9 28.3 1.4 9.1 2.6 5.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.6 132089.4_18525001_1 - 0.26 11.5 29.2 0.1 12.8 0.5 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Spc97_Spc98 PF04130.11 001169327.2_18527001_2 - 1.3e-102 344.2 17.1 2.7e-102 343.2 17.1 1.5 1 1 0 1 1 1 1 Spc97 / Spc98 family Glyco_transf_5 PF08323.9 001169327.2_18527001_2 - 0.038 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain p450 PF00067.20 080292.4_18525001_3 - 9.3e-95 317.9 0.0 1.2e-94 317.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FixQ PF05545.9 080292.4_18525001_3 - 0.051 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Peptidase_M14 PF00246.22 206596.2_18529001_1 - 6.3e-159 528.2 0.0 2.7e-81 273.4 0.0 4.1 4 1 0 4 4 4 3 Zinc carboxypeptidase CarboxypepD_reg PF13620.4 206596.2_18529001_1 - 1.9e-44 149.7 0.0 5e-14 52.2 0.0 4.5 4 0 0 4 4 4 4 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.4 206596.2_18529001_1 - 4.3e-20 71.4 0.0 1.1e-05 25.2 0.0 4.7 4 0 0 4 4 4 4 CarboxypepD_reg-like domain AstE_AspA PF04952.12 206596.2_18529001_1 - 0.00011 21.3 0.2 0.0074 15.3 0.0 2.3 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family PEGA PF08308.9 206596.2_18529001_1 - 0.00023 20.8 0.0 6.4 6.6 0.0 4.5 4 0 0 4 4 4 2 PEGA domain DUF1416 PF07210.10 206596.2_18529001_1 - 0.0023 17.7 0.1 0.76 9.6 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1416) Dioxygenase_C PF00775.19 206596.2_18529001_1 - 0.021 14.1 0.3 1.1e+02 2.1 0.0 4.7 5 0 0 5 5 5 0 Dioxygenase UCH PF00443.27 167037.2_18529001_1 - 4.8e-41 140.8 0.1 3.3e-35 121.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.17 167037.2_18529001_1 - 1.9e-21 76.0 3.9 1.9e-21 76.0 3.9 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.4 167037.2_18529001_1 - 8.3e-08 32.1 2.6 2e-05 24.3 0.9 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PT-VENN PF04829.11 001297954.1_18524001_2 - 0.82 9.7 6.1 1 9.4 3.6 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Pkinase PF00069.23 130616.3_18529001_3 - 3.3e-74 249.4 0.0 5.4e-74 248.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 130616.3_18529001_3 - 7.7e-41 139.9 0.0 1.2e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 130616.3_18529001_3 - 7.7e-08 31.9 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like COPIIcoated_ERV PF07970.10 001272170.1_18524001_3 - 9.6e-34 117.0 0.0 1.4e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.4 001272170.1_18524001_3 - 4.5e-20 71.7 0.1 8.5e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) 7tm_1 PF00001.19 001272241.2_18526001_1 - 3.4e-47 160.8 6.4 4.8e-47 160.3 6.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001272241.2_18526001_1 - 1.7e-11 43.8 13.8 7.5e-11 41.8 13.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.7 001272241.2_18526001_1 - 1.8e-09 37.3 12.3 3.9e-08 32.8 6.5 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.7 001272241.2_18526001_1 - 1.2e-07 31.2 8.3 1.2e-07 31.2 8.3 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.7 001272241.2_18526001_1 - 2e-05 23.9 0.5 2e-05 23.9 0.5 2.6 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srw zf-RING_2 PF13639.4 130613.3_18522001_2 - 1.2e-12 47.7 7.8 2.4e-12 46.8 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 130613.3_18522001_2 - 1.2e-09 38.1 8.0 3.6e-09 36.7 8.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.4 130613.3_18522001_2 - 1.9e-08 34.0 6.4 3.3e-08 33.2 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.4 130613.3_18522001_2 - 2e-08 33.8 5.4 3.2e-08 33.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 130613.3_18522001_2 - 3.5e-08 33.2 1.1 5.1e-08 32.7 0.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 130613.3_18522001_2 - 1.6e-07 31.0 4.6 2.8e-07 30.2 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 130613.3_18522001_2 - 1.8e-07 30.7 5.4 1.8e-07 30.7 5.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.3 130613.3_18522001_2 - 2.1e-07 30.4 1.9 2.1e-07 30.4 1.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.4 130613.3_18522001_2 - 2.3e-07 30.4 4.4 5.4e-07 29.2 4.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.5 130613.3_18522001_2 - 0.00063 19.6 4.3 0.0017 18.2 4.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zf_RING PF16744.3 130613.3_18522001_2 - 0.00066 19.6 3.9 0.0019 18.1 3.9 1.7 1 1 0 1 1 1 1 KIAA1045 RING finger Zn_ribbon_17 PF17120.3 130613.3_18522001_2 - 0.0011 18.4 5.0 0.0023 17.4 5.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.4 130613.3_18522001_2 - 0.0058 16.4 1.6 0.0058 16.4 1.6 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.4 130613.3_18522001_2 - 0.0089 15.6 5.1 0.016 14.8 5.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.9 130613.3_18522001_2 - 0.016 15.4 7.8 0.037 14.2 7.8 1.6 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.5 130613.3_18522001_2 - 0.017 15.1 5.8 0.041 13.9 5.8 1.7 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.27 130613.3_18522001_2 - 0.025 14.3 6.4 0.025 14.3 6.4 2.0 2 1 1 3 3 2 0 PHD-finger zf-RING_10 PF16685.3 130613.3_18522001_2 - 0.037 14.0 0.8 0.067 13.2 0.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.4 130613.3_18522001_2 - 0.041 13.9 1.7 0.16 12.0 1.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_9 PF13901.4 130613.3_18522001_2 - 0.08 12.8 5.2 0.13 12.1 5.2 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.6 130613.3_18522001_2 - 0.13 12.3 6.9 0.56 10.3 6.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.4 130613.3_18522001_2 - 0.28 11.3 5.3 0.39 10.9 1.3 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-Di19 PF05605.10 130613.3_18522001_2 - 0.31 11.2 4.4 6.5 7.0 0.8 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.4 130613.3_18522001_2 - 1.4 9.8 0.0 1.4 9.8 0.0 3.0 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C3H2C3 PF17122.3 130613.3_18522001_2 - 2.9 7.9 5.8 6.9 6.7 5.8 1.7 1 1 0 1 1 1 0 Zinc-finger Zn-ribbon_8 PF09723.8 130613.3_18522001_2 - 3.9 7.5 5.3 1.6 8.8 1.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Fib_alpha PF08702.8 001258784.2_18524001_1 - 0.0048 16.9 9.8 0.0048 16.9 9.8 3.3 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family Telomere_reg-2 PF10193.7 001258784.2_18524001_1 - 0.078 13.3 0.9 0.34 11.2 0.9 2.1 1 0 0 1 1 1 0 Telomere length regulation protein Ribosomal_S30AE PF02482.17 001258784.2_18524001_1 - 0.99 10.1 7.6 3.5 8.3 2.3 3.3 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein RRM_1 PF00076.20 001103495.5_18529001_1 - 2.7e-55 184.0 1.4 2.7e-20 71.8 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001103495.5_18529001_1 - 5.7e-07 29.0 0.0 0.00062 19.2 0.0 4.0 2 1 2 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.16 001103532.3_18529001_3 - 4.2e-38 128.2 71.3 6.7e-08 31.6 4.9 6.6 6 0 0 6 6 6 6 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.13 001103532.3_18529001_3 - 0.33 10.9 16.8 11 6.0 0.2 6.1 6 0 0 6 6 6 0 Sec23/Sec24 zinc finger Trypsin PF00089.24 132922.3_18522001_2 - 4.3e-44 150.8 0.1 5.2e-44 150.5 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 132922.3_18522001_2 - 5e-05 24.1 0.0 7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF4588 PF15251.4 132936.4_18524001_1 - 1.3e-38 133.1 0.0 3e-38 131.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) Thymosin PF01290.18 167002.3_18522001_1 - 9.9e-16 57.0 5.8 1.6e-15 56.4 5.8 1.3 1 0 0 1 1 1 1 Thymosin beta-4 family DUF2556 PF10831.6 167002.3_18522001_1 - 0.23 11.2 0.4 0.37 10.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Thymosin PF01290.18 167002.3_18522001_3 - 3.3e-27 93.8 8.3 3.2e-16 58.6 1.7 2.2 2 0 0 2 2 2 2 Thymosin beta-4 family Homeobox PF00046.27 001272713.1_18526001_3 - 5.4e-23 80.4 6.4 1.3e-22 79.2 6.4 1.7 1 0 0 1 1 1 1 Homeobox domain DUF2561 PF10812.6 001316635.1_18529001_1 - 0.052 13.5 1.1 0.099 12.5 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DENN PF02141.19 001316635.1_18529001_2 - 4.5e-31 108.1 4.1 4.5e-31 108.1 4.1 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.16 001316635.1_18529001_2 - 6.4e-18 65.2 0.3 2.6e-17 63.2 0.3 2.2 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.17 001316635.1_18529001_2 - 0.22 11.4 2.5 0.76 9.7 1.1 2.5 2 0 0 2 2 2 0 dDENN domain SBF2 PF12335.6 001316635.1_18529001_2 - 0.68 9.4 4.9 0.68 9.4 0.0 2.4 2 0 0 2 2 2 0 Myotubularin protein CPSF100_C PF13299.4 001316635.1_18529001_2 - 8.5 6.4 6.8 34 4.4 2.7 2.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal IBR PF01485.19 206777.2_18526001_2 - 1.6e-16 60.1 31.3 4e-13 49.2 8.7 6.2 6 1 0 6 6 6 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.4 206777.2_18526001_2 - 2.9e-05 23.7 3.0 2.9e-05 23.7 3.0 5.4 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 206777.2_18526001_2 - 0.0002 21.4 3.6 0.0002 21.4 3.6 4.5 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.23 206777.2_18526001_2 - 0.0003 20.5 2.7 0.0003 20.5 2.7 5.7 5 1 1 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 206777.2_18526001_2 - 0.0027 17.5 4.1 0.0027 17.5 4.1 4.2 4 1 0 4 4 4 2 RING-type zinc-finger zf-C3HC4_4 PF15227.4 206777.2_18526001_2 - 1.1 9.3 28.6 0.33 11.0 1.3 4.9 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING IBR PF01485.19 001272743.1_18527001_1 - 1.1e-16 60.7 57.0 4.9e-13 49.0 8.7 5.7 5 1 0 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.4 001272743.1_18527001_1 - 3.5e-05 23.4 3.0 3.5e-05 23.4 3.0 5.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001272743.1_18527001_1 - 0.00025 21.1 3.6 0.00025 21.1 3.6 4.5 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.23 001272743.1_18527001_1 - 0.00037 20.2 2.7 0.00037 20.2 2.7 5.7 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001272743.1_18527001_1 - 0.0034 17.2 4.1 0.0034 17.2 4.1 4.3 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001272743.1_18527001_1 - 0.51 10.4 26.5 0.17 11.9 2.2 4.8 4 1 1 5 5 5 0 zinc finger of C3HC4-type, RING EF-hand_7 PF13499.4 133043.3_18529001_1 - 4.2e-22 78.3 4.0 4.4e-17 62.2 0.9 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 133043.3_18529001_1 - 1e-21 74.7 5.2 3.5e-06 26.0 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.4 133043.3_18529001_1 - 1.2e-18 65.6 3.9 9.9e-06 24.7 0.4 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.4 133043.3_18529001_1 - 1.6e-17 61.7 4.3 0.00031 20.3 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.4 133043.3_18529001_1 - 2.4e-13 49.5 3.1 1.1e-05 25.0 0.5 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.5 133043.3_18529001_1 - 0.014 15.2 3.5 0.91 9.4 0.0 3.3 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 133043.3_18529001_1 - 0.082 13.1 5.5 0.55 10.4 1.5 3.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region NRDE-2 PF08424.8 132786.4_18528001_3 - 5.8e-21 74.8 3.6 3.6e-20 72.2 2.6 2.2 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference Lipase PF00151.17 001297993.1_18528001_1 - 1.2e-84 284.4 0.0 1.7e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_1 PF00561.18 001297993.1_18528001_1 - 0.00015 21.4 0.3 0.00023 20.8 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001297993.1_18528001_1 - 0.00037 21.0 4.3 0.00057 20.4 4.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase PF00151.17 132058.3_18526001_3 - 6.3e-85 285.3 0.0 8e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_1 PF00561.18 132058.3_18526001_3 - 9.4e-05 22.0 0.3 0.00014 21.4 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 132058.3_18526001_3 - 0.00025 21.6 4.5 0.0004 21.0 4.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Unpaired PF15972.3 080356.4_18526001_1 - 7.6e-106 353.5 11.1 1.3e-105 352.7 11.1 1.4 1 0 0 1 1 1 1 Unpaired protein Serglycin PF04360.10 080356.4_18526001_1 - 0.44 10.3 4.3 0.083 12.7 0.6 1.6 2 0 0 2 2 2 0 Serglycin Unpaired PF15972.3 001298473.1_18526001_3 - 8.3e-106 353.4 11.1 1.3e-105 352.7 11.1 1.3 1 0 0 1 1 1 1 Unpaired protein Spt5_N PF11942.6 001298473.1_18526001_3 - 0.25 12.2 2.1 0.79 10.6 2.1 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Serglycin PF04360.10 001298473.1_18526001_3 - 0.93 9.3 5.4 0.12 12.2 1.0 1.7 2 0 0 2 2 2 0 Serglycin PET117 PF15786.3 001298473.1_18526001_3 - 6.9 6.9 10.1 3.7 7.7 7.4 2.0 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Topoisom_I PF01028.18 001258750.2_18529001_2 - 6.7e-100 332.9 7.6 1.2e-99 332.0 7.6 1.5 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.13 001258750.2_18529001_2 - 8.9e-96 319.3 2.9 8.9e-96 319.3 2.9 3.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.4 001258750.2_18529001_2 - 5.2e-34 115.8 0.4 5.2e-34 115.8 0.4 2.3 2 0 0 2 2 2 1 C-terminal topoisomerase domain 60KD_IMP PF02096.18 001297824.1_18529001_3 - 0.15 11.9 0.4 0.3 10.8 0.4 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Homeobox PF00046.27 001298460.1_18526001_3 - 2.5e-21 75.1 2.5 5.6e-21 74.0 2.5 1.6 1 0 0 1 1 1 1 Homeobox domain Metallopep PF12044.6 132798.3_18525001_2 - 2.1e-98 329.6 0.0 3.5e-98 328.9 0.0 1.3 1 1 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.4 132798.3_18525001_2 - 0.025 15.0 0.3 0.053 13.9 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SR-25 PF10500.7 132798.3_18525001_2 - 0.13 11.7 6.2 0.22 11.0 6.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Reprolysin_5 PF13688.4 132798.3_18525001_2 - 0.19 11.7 2.2 0.4 10.7 1.8 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12 zf-C4_Topoisom PF01396.17 132798.3_18525001_2 - 0.29 10.8 2.1 7.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger IMUP PF15761.3 132798.3_18525001_2 - 0.85 10.2 6.0 1.6 9.3 6.0 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein AF-4 PF05110.11 132798.3_18525001_2 - 5.8 4.7 6.5 8.2 4.2 6.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4597 PF15366.4 132798.3_18525001_3 - 0.27 10.9 3.6 0.27 10.9 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) GLTP PF08718.9 001298341.1_18523001_2 - 4.5e-35 121.0 0.0 7.5e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) SPX PF03105.17 001298344.1_18528001_1 - 0.68 9.7 15.6 1 9.1 15.6 1.1 1 0 0 1 1 1 0 SPX domain FtsJ PF01728.17 001297922.1_18527001_1 - 3.3e-37 128.2 0.0 5.4e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.21 001297922.1_18527001_1 - 5e-14 51.8 2.3 8.3e-14 51.1 2.3 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.5 001297922.1_18527001_1 - 0.0027 17.6 1.1 0.0051 16.7 1.1 1.4 1 0 0 1 1 1 1 G-patch domain Phage-scaffold PF09306.8 001297922.1_18527001_1 - 0.021 14.1 0.1 0.033 13.4 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein Asparaginase PF00710.18 130732.2_18526001_2 - 2.3e-64 216.3 0.0 3.4e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Ank_2 PF12796.5 130732.2_18526001_2 - 7e-23 80.9 0.8 4.6e-14 52.6 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.4 130732.2_18526001_2 - 6.1e-19 68.0 1.2 5.1e-10 39.6 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.4 130732.2_18526001_2 - 1.6e-17 61.7 0.1 5.5e-06 26.2 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.4 130732.2_18526001_2 - 9.2e-17 60.7 0.4 7.9e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.28 130732.2_18526001_2 - 2.8e-14 52.7 0.2 1.1e-05 25.5 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Lipase PF00151.17 001298468.1_18529001_2 - 7.5e-75 252.2 0.0 5.3e-74 249.4 0.0 2.0 1 1 1 2 2 2 1 Lipase Cofilin_ADF PF00241.18 133095.2_18522001_1 - 4.5e-15 55.8 0.0 6.4e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein 7tm_1 PF00001.19 001014723.2_18527001_3 - 1.1e-20 73.8 14.7 2.2e-10 40.1 1.7 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.7 001014723.2_18527001_3 - 1.1e-18 67.5 19.2 1e-10 41.3 8.9 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.7 001014723.2_18527001_3 - 3.2e-06 26.6 20.5 0.00079 18.7 3.3 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx HTH_Tnp_1 PF01527.18 001014723.2_18527001_3 - 0.021 15.0 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Transposase PDGF PF00341.15 001169321.2_18524001_2 - 1.1e-22 80.0 8.0 1.1e-22 80.0 8.0 2.3 2 0 0 2 2 2 1 PDGF/VEGF domain Ribosom_S12_S23 PF00164.23 001258561.1_18524001_3 - 2.7e-23 82.0 0.4 5e-23 81.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Transformer PF06495.9 001258575.1_18524001_1 - 4.3 7.2 6.3 8.6 6.3 6.3 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Tetraspannin PF00335.18 001258575.1_18524001_2 - 2.7e-49 167.7 13.1 4.4e-49 167.0 13.1 1.3 1 0 0 1 1 1 1 Tetraspanin family Carb_anhydrase PF00194.19 001258664.2_18525001_1 - 1.3e-74 250.9 0.0 1.7e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Glyco_hydro_18 PF00704.26 001258672.2_18529001_1 - 2.3e-94 316.5 2.0 2.3e-94 316.5 2.0 3.2 4 0 0 4 4 4 1 Glycosyl hydrolases family 18 CBM_14 PF01607.22 001258672.2_18529001_1 - 2.2e-14 53.2 3.6 4.1e-14 52.3 3.6 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Ig_3 PF13927.4 001258674.2_18527001_3 - 8.4e-06 26.2 0.2 3.6e-05 24.2 0.2 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001258674.2_18527001_3 - 0.0022 18.1 0.3 0.0054 16.9 0.3 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001258674.2_18527001_3 - 0.0088 16.1 0.1 0.0088 16.1 0.1 2.2 3 0 0 3 3 3 1 Immunoglobulin domain Aldo_ket_red PF00248.19 001258683.2_18528001_2 - 1.9e-74 250.3 0.0 3.5e-74 249.5 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4205 PF13898.4 133110.3_18525001_2 - 6.5e-56 189.6 0.0 3.3e-50 170.8 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) EF-hand_7 PF13499.4 133110.3_18525001_2 - 0.12 12.7 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.4 133110.3_18525001_2 - 0.16 11.8 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Miga PF10265.7 133110.3_18525001_2 - 0.19 10.6 6.2 0.35 9.6 6.2 1.3 1 0 0 1 1 1 0 Mitoguardin Anoctamin PF04547.10 001258704.1_18529001_3 - 4.8e-140 467.1 13.1 6.2e-140 466.7 13.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.3 001258704.1_18529001_3 - 2.7e-52 177.6 0.8 4e-52 177.1 0.8 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.7 001258704.1_18529001_3 - 0.85 8.2 3.0 1.9 7.0 2.9 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Fer2_3 PF13085.4 001298491.1_18524001_1 - 8.3e-33 112.5 0.3 1.4e-32 111.8 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.4 001298491.1_18524001_1 - 1e-08 35.4 6.1 1e-08 35.4 6.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.4 001298491.1_18524001_1 - 1.4e-07 31.7 7.0 1.4e-07 31.7 7.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.4 001298491.1_18524001_1 - 2e-06 27.7 3.1 2e-06 27.7 3.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.25 001298491.1_18524001_1 - 0.014 15.2 2.4 0.014 15.2 2.4 1.7 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.4 001298491.1_18524001_1 - 0.017 15.1 5.2 0.017 15.1 5.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Mito_fiss_reg PF05308.9 001298491.1_18524001_1 - 1.3 9.0 3.4 2.4 8.0 3.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Fer4_7 PF12838.5 001298491.1_18524001_1 - 6.1 7.4 15.5 0.83 10.2 8.8 2.8 2 2 1 3 3 3 0 4Fe-4S dicluster domain AMP-binding PF00501.26 001258744.1_18526001_3 - 2.1e-91 306.5 0.0 2.6e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001258744.1_18526001_3 - 8.7e-19 68.2 0.9 2e-18 67.0 0.9 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pou PF00157.15 001258753.2_18526001_1 - 2.4e-30 104.2 0.0 5.1e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001258753.2_18526001_1 - 1.8e-16 59.6 0.7 4.1e-16 58.4 0.7 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.4 001258753.2_18526001_1 - 0.027 14.7 5.0 0.046 13.9 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Pou PF00157.15 001258757.2_18526001_1 - 2.3e-30 104.3 0.0 5e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001258757.2_18526001_1 - 8e-17 60.7 1.0 1.8e-16 59.5 1.0 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.4 001258757.2_18526001_1 - 0.02 15.1 4.6 0.045 14.0 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain TIL PF01826.15 001258809.2_18521001_3 - 0.02 15.0 13.9 0.034 14.3 13.9 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Helo_like_N PF17111.3 001258809.2_18521001_3 - 0.73 9.0 2.5 0.96 8.6 2.5 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Sds3 PF08598.9 001258830.2_18524001_3 - 1.7e-13 50.9 15.1 3.3e-13 50.0 15.1 1.4 1 1 0 1 1 1 1 Sds3-like CBM_14 PF01607.22 001258850.2_18523001_1 - 8.2e-28 96.2 24.3 2.3e-10 40.3 4.6 3.8 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Sid-5 PF17204.1 001258850.2_18523001_2 - 0.083 12.9 1.1 0.16 12.1 1.1 1.4 1 0 0 1 1 1 0 Sid-5 family UCH PF00443.27 001258871.2_18529001_1 - 8e-65 218.7 2.3 1.6e-64 217.7 2.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 001258871.2_18529001_1 - 3.8e-22 79.2 3.2 3.8e-22 79.2 3.2 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PRIMA1 PF16101.3 001258871.2_18529001_3 - 5.9 6.8 11.1 15 5.5 11.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribosomal_L36e PF01158.16 057281.4_18522001_3 - 1.4e-40 137.3 9.4 1.8e-40 136.9 9.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Asparaginase_2 PF01112.16 132811.3_18523001_1 - 1.4e-93 313.2 1.1 1.8e-93 312.8 1.1 1.1 1 0 0 1 1 1 1 Asparaginase CBM_14 PF01607.22 001298502.1_18523001_1 - 2e-08 34.2 10.7 0.00034 20.6 0.3 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain MFS_1 PF07690.14 001298505.1_18525001_3 - 6e-23 81.2 34.5 2e-16 59.7 7.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.26 001298353.1_18524001_3 - 8.9e-19 67.7 0.2 2.1e-18 66.5 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain DUF4952 PF16310.3 001298353.1_18524001_3 - 0.041 14.1 0.3 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Domian of unknown function (DUF4952) DUF913 PF06025.10 001298360.1_18529001_3 - 7.8e-100 334.2 0.0 7.8e-100 334.2 0.0 5.2 3 1 0 3 3 3 1 Domain of Unknown Function (DUF913) HECT PF00632.23 001298360.1_18529001_3 - 5.2e-90 301.9 0.6 8.7e-90 301.2 0.6 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.4 001298360.1_18529001_3 - 3.8e-25 88.3 10.9 3.8e-25 88.3 10.9 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) DUF908 PF06012.10 001298360.1_18529001_3 - 2.1e-12 47.0 7.1 3.3e-11 43.1 3.1 6.1 5 2 1 6 6 6 2 Domain of Unknown Function (DUF908) WWE PF02825.18 001298360.1_18529001_3 - 1.7e-10 41.2 0.4 6.6e-10 39.3 0.4 2.1 1 0 0 1 1 1 1 WWE domain UBA PF00627.29 001298360.1_18529001_3 - 5.4e-06 26.1 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.8 001298360.1_18529001_3 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Como_LCP PF02247.14 001298360.1_18529001_3 - 0.11 11.0 0.1 0.18 10.2 0.1 1.2 1 0 0 1 1 1 0 Large coat protein DUF913 PF06025.10 001298362.1_18529001_3 - 1.8e-100 336.4 8.8 8e-100 334.2 0.0 4.8 3 1 0 3 3 3 1 Domain of Unknown Function (DUF913) HECT PF00632.23 001298362.1_18529001_3 - 5.3e-90 301.9 0.6 8.9e-90 301.1 0.6 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.4 001298362.1_18529001_3 - 3.9e-25 88.3 10.9 3.9e-25 88.3 10.9 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) DUF908 PF06012.10 001298362.1_18529001_3 - 2.2e-12 47.0 7.0 2.9e-11 43.3 3.0 5.8 4 2 1 5 5 5 2 Domain of Unknown Function (DUF908) WWE PF02825.18 001298362.1_18529001_3 - 1.7e-10 41.1 0.4 6.8e-10 39.2 0.4 2.1 1 0 0 1 1 1 1 WWE domain UBA PF00627.29 001298362.1_18529001_3 - 5.6e-06 26.0 0.0 1.4e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.8 001298362.1_18529001_3 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Como_LCP PF02247.14 001298362.1_18529001_3 - 0.11 10.9 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Large coat protein Staphylcoagulse PF04022.10 001298450.1_18524001_1 - 0.24 10.8 0.9 0.7 9.3 0.9 1.7 1 0 0 1 1 1 0 Staphylocoagulase repeat Chromo PF00385.22 001298450.1_18524001_2 - 1.7e-10 40.5 0.5 3.2e-10 39.6 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TEA PF01285.16 206727.3_18526001_2 - 5.7e-27 94.8 0.3 1.4e-26 93.5 0.0 1.7 2 0 0 2 2 2 1 TEA/ATTS domain family TEA PF01285.16 001103520.3_18527001_2 - 7e-27 94.5 0.2 1.7e-26 93.2 0.0 1.6 2 0 0 2 2 2 1 TEA/ATTS domain family CH PF00307.29 078661.4_18527001_1 - 4.7e-85 280.8 4.8 5.3e-22 77.9 0.1 4.5 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.6 078661.4_18527001_1 - 3.2e-07 30.0 0.0 0.001 18.8 0.1 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_7 PF13499.4 078661.4_18527001_1 - 7.1e-06 26.3 0.4 2.3e-05 24.6 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.30 078661.4_18527001_1 - 2.3e-05 23.5 2.0 0.00017 20.8 0.6 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.4 078661.4_18527001_1 - 3e-05 23.5 0.4 3e-05 23.5 0.4 2.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.4 078661.4_18527001_1 - 0.00015 21.0 1.5 0.00085 18.6 0.6 2.5 2 0 0 2 2 2 1 EF hand PgpA PF04608.11 078661.4_18527001_1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A HA2 PF04408.21 001298440.1_18529001_1 - 1.2e-13 51.2 0.0 2.9e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.29 001298440.1_18529001_1 - 1.4e-12 47.9 0.0 3.3e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain R3H PF01424.20 001298440.1_18529001_1 - 1.7e-09 37.4 0.6 6.4e-09 35.5 0.1 2.2 2 0 0 2 2 2 1 R3H domain DEAD PF00270.27 001298440.1_18529001_1 - 1.7e-08 34.3 0.6 5e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.14 001298440.1_18529001_1 - 1.9e-08 34.2 0.0 5.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.4 001298440.1_18529001_1 - 6.1e-06 26.5 1.8 6.2e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.4 001298440.1_18529001_1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.13 001298440.1_18529001_1 - 0.00031 20.6 0.0 0.00072 19.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.18 001298440.1_18529001_1 - 0.0059 15.6 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.12 001298440.1_18529001_1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.4 001298440.1_18529001_1 - 0.026 14.6 0.4 0.23 11.6 0.2 2.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.4 001298440.1_18529001_1 - 0.054 12.9 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.10 001298440.1_18529001_1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.4 001298440.1_18529001_1 - 0.1 12.1 0.1 0.32 10.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF126 PF01989.14 001298440.1_18529001_1 - 0.12 12.1 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF126 PBC PF03792.11 001272663.2_18526001_2 - 2.5e-93 311.0 1.8 3.5e-93 310.5 1.8 1.2 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.27 001272663.2_18526001_2 - 1.3e-18 66.4 0.6 2.5e-18 65.5 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001272663.2_18526001_2 - 2.3e-15 56.1 0.0 5.4e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Nucleoporin_FG2 PF15967.3 001272663.2_18526001_2 - 0.0035 15.8 2.2 0.0037 15.7 1.3 1.4 1 1 0 1 1 1 1 Nucleoporin FG repeated region YdaS_antitoxin PF15943.3 001272663.2_18526001_2 - 0.011 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.20 001272663.2_18526001_2 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix P21-Arc PF04062.12 132965.2_18522001_3 - 2.3e-70 236.0 0.0 2.6e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit WW PF00397.24 001272707.1_18529001_2 - 5.2e-09 35.8 0.5 1.2e-08 34.7 0.5 1.6 1 0 0 1 1 1 1 WW domain Tektin PF03148.12 167765.4_18525001_2 - 1e-129 432.5 21.9 1.2e-129 432.3 21.9 1.0 1 0 0 1 1 1 1 Tektin family Baculo_PEP_C PF04513.10 167765.4_18525001_2 - 1.1 9.2 4.2 3.1 7.7 0.4 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.10 167765.4_18525001_2 - 1.5 8.7 11.7 0.87 9.4 4.7 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Clathrin PF00637.18 206729.2_18529001_1 - 2.9e-201 659.3 41.0 6.6e-33 113.5 2.8 8.1 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.18 206729.2_18529001_1 - 2.4e-48 160.0 3.6 5.9e-08 32.5 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.4 206729.2_18529001_1 - 9.6e-29 99.0 1.5 5.3e-28 96.6 1.1 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.8 206729.2_18529001_1 - 3.7e-12 45.2 0.3 9.6e-12 43.9 0.3 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.12 206729.2_18529001_1 - 8.4e-06 25.0 7.0 0.0014 17.7 0.1 4.0 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.4 206729.2_18529001_1 - 0.0051 16.6 7.5 5.3 7.2 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat PSD2 PF07624.9 206729.2_18529001_1 - 0.088 12.5 0.1 0.46 10.2 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Alpha-amylase_C PF02806.16 206729.2_18529001_1 - 0.11 12.9 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain TPR_1 PF00515.26 206729.2_18529001_1 - 0.31 10.8 0.0 0.31 10.8 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.4 206729.2_18529001_1 - 0.82 10.5 14.5 12 6.9 0.1 6.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.4 206729.2_18529001_1 - 3.8 8.0 8.0 9.6 6.7 0.3 4.9 6 1 0 6 6 4 0 Tetratricopeptide repeat TPR_2 PF07719.15 206729.2_18529001_1 - 6.3 7.0 15.1 7.9 6.7 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat BTB PF00651.29 166897.2_18528001_2 - 1.4e-25 89.5 0.3 2.5e-25 88.7 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.4 166897.2_18528001_2 - 1.4e-05 24.8 8.8 9.7e-05 22.1 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.24 166897.2_18528001_2 - 0.015 15.6 15.1 0.051 13.9 2.2 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.5 166897.2_18528001_2 - 0.09 13.1 6.6 6 7.3 0.2 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 166897.2_18528001_2 - 0.22 11.7 6.3 0.9 9.8 1.0 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.19 166897.2_18528001_2 - 0.47 10.5 2.9 1.2 9.2 2.9 1.6 1 0 0 1 1 1 0 FYVE zinc finger COX17 PF05051.11 132770.2_18522001_1 - 9.5e-20 70.6 9.5 1.8e-19 69.7 9.5 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) NIPSNAP PF07978.11 001298387.1_18523001_3 - 1.9e-41 140.3 0.9 5.2e-31 106.8 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP Fascin PF06268.11 167143.3_18527001_2 - 4.5e-90 297.2 3.6 2.3e-33 114.6 0.0 4.4 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.10 167143.3_18527001_2 - 9.1e-13 48.2 1.0 0.022 14.3 0.0 5.4 4 2 2 6 6 6 4 FRG1-like domain DUF569 PF04601.11 167143.3_18527001_2 - 0.058 12.9 0.1 2 8.0 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF569) RRM_1 PF00076.20 167175.3_18522001_2 - 9.6e-05 22.0 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3291 PF11695.6 167175.3_18522001_2 - 0.035 13.7 0.3 0.061 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) DUF3421 PF11901.6 132670.4_18523001_2 - 3.5e-86 284.8 4.6 1.1e-39 134.8 0.3 4.3 1 1 3 4 4 4 4 Protein of unknown function (DUF3421) DUF2782 PF11191.6 132670.4_18523001_2 - 0.0066 16.5 0.1 9.8 6.3 0.0 3.3 2 1 0 3 3 3 2 Protein of unknown function (DUF2782) TBP PF00352.19 001103435.3_18529001_1 - 1.2e-43 146.8 0.0 3.6e-21 74.8 0.0 2.8 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) adh_short PF00106.23 132518.3_18523001_2 - 3.7e-43 147.1 0.3 4.6e-43 146.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 132518.3_18523001_2 - 5.2e-27 94.8 0.1 6.5e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 132518.3_18523001_2 - 0.00012 22.0 0.2 0.00015 21.6 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.4 132518.3_18523001_2 - 0.00017 21.4 0.1 0.00024 21.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.19 132518.3_18523001_2 - 0.00026 20.4 0.2 0.0011 18.3 0.1 2.1 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 132518.3_18523001_2 - 0.09 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DAGK_acc PF00609.17 001103446.2_18528001_3 - 1.2e-46 158.8 0.0 2.3e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain Ank_2 PF12796.5 001103446.2_18528001_3 - 1e-29 102.8 12.8 2e-16 60.2 1.9 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DAGK_cat PF00781.22 001103446.2_18528001_3 - 7.3e-29 99.8 0.0 1.8e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.20 001103446.2_18528001_3 - 8.1e-21 73.5 24.1 7.7e-13 48.0 10.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_4 PF13637.4 001103446.2_18528001_3 - 2.9e-15 56.3 0.9 6.9e-10 39.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.4 001103446.2_18528001_3 - 4.7e-15 55.3 1.8 2.4e-08 34.0 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 001103446.2_18528001_3 - 1.6e-12 46.3 0.9 0.0002 21.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.28 001103446.2_18528001_3 - 3.5e-09 36.6 1.0 0.0044 17.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DUF3915 PF13054.4 001103446.2_18528001_3 - 7.3 6.5 7.3 6.3 6.7 3.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) PT PF04886.10 167509.3_18529001_2 - 0.00027 20.3 4.2 0.00027 20.3 4.2 1.8 2 0 0 2 2 2 1 PT repeat Peptidase_S8 PF00082.20 167509.3_18529001_3 - 4.3e-48 163.9 1.2 8.8e-48 162.9 1.2 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.18 167509.3_18529001_3 - 1.9e-25 88.6 0.0 3.8e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.3 167509.3_18529001_3 - 9.6e-24 83.9 3.1 1.9e-23 83.0 3.1 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain GF_recep_IV PF14843.4 167509.3_18529001_3 - 8.4e-21 74.0 174.6 5.7e-14 51.9 29.8 6.2 1 1 4 5 5 5 3 Growth factor receptor domain IV Furin-like_2 PF15913.3 167509.3_18529001_3 - 4.9e-09 36.2 82.7 1.3e-05 25.2 17.6 7.9 1 1 6 7 7 7 4 Furin-like repeat, cysteine-rich Furin-like PF00757.18 167509.3_18529001_3 - 1.3e-07 31.5 26.8 1.3e-07 31.5 26.8 6.4 1 1 5 6 6 6 3 Furin-like cysteine rich region VSP PF03302.11 167509.3_18529001_3 - 4.1e-05 22.5 156.3 0.0012 17.7 5.6 9.7 1 1 8 9 9 9 5 Giardia variant-specific surface protein PT PF04886.10 167509.3_18529001_3 - 0.076 12.4 11.5 0.039 13.4 8.3 2.2 2 0 0 2 2 2 0 PT repeat AAA_34 PF13872.4 001103497.2_18529001_3 - 4.1e-141 469.1 0.0 6.4e-141 468.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.4 001103497.2_18529001_3 - 4.4e-123 410.0 0.0 7.8e-123 409.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.13 001103497.2_18529001_3 - 2.7e-08 33.9 0.5 5e-07 29.7 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.29 001103497.2_18529001_3 - 0.00087 19.5 0.2 0.0038 17.4 0.2 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CENP-B_dimeris PF09026.8 001103497.2_18529001_3 - 3.1 8.1 27.9 0.74 10.1 5.6 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BUD22 PF09073.8 001103497.2_18529001_3 - 8.8 5.4 36.5 4.9 6.3 29.0 2.5 2 0 0 2 2 2 0 BUD22 RasGAP PF00616.17 001103542.4_18529001_1 - 9e-23 80.9 0.1 3.1e-15 56.3 0.0 4.9 4 2 1 5 5 5 3 GTPase-activator protein for Ras-like GTPase DUF3498 PF12004.6 001103542.4_18529001_1 - 7.3e-16 58.3 5.0 7.3e-16 58.3 5.0 5.3 5 1 0 5 5 5 1 Domain of unknown function (DUF3498) C2 PF00168.28 001103542.4_18529001_1 - 1.1e-10 41.6 0.1 2.2e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 C2 domain PH PF00169.27 001103542.4_18529001_1 - 0.0036 17.7 0.0 0.025 14.9 0.0 2.5 2 0 0 2 2 2 1 PH domain 7tm_1 PF00001.19 001103551.2_18527001_1 - 3.8e-58 196.7 2.5 5.3e-58 196.2 2.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001103551.2_18527001_1 - 1.3e-06 27.9 15.2 0.00092 18.5 6.5 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001103551.2_18527001_1 - 2.2e-06 27.5 7.3 4.8e-06 26.4 7.3 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001103551.2_18527001_1 - 3.9e-06 26.2 9.8 1e-05 24.9 9.8 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx ABC_cobalt PF09819.7 001103551.2_18527001_1 - 0.098 12.7 3.0 0.22 11.6 3.0 1.5 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component EMP24_GP25L PF01105.22 167637.2_18524001_1 - 0.0079 16.0 0.0 0.017 14.9 0.0 1.6 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Casc1_N PF15927.3 167637.2_18524001_1 - 1.1 8.7 5.8 1.2 8.7 0.8 2.1 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DASH_Hsk3 PF08227.9 167637.2_18524001_1 - 2 8.7 5.6 3.1 8.1 2.9 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like ELM2 PF01448.22 001014755.2_18525001_1 - 3e-14 53.4 0.2 7.1e-14 52.2 0.2 1.7 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.29 001014755.2_18525001_1 - 6e-05 23.0 0.5 0.00013 21.9 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C2H2_4 PF13894.4 167685.3_18529001_3 - 9e-07 29.1 55.3 0.029 15.1 1.0 7.5 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.24 167685.3_18529001_3 - 9.4e-07 28.8 63.0 0.022 15.1 6.2 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 167685.3_18529001_3 - 2.3e-06 27.7 48.5 0.0099 16.2 2.1 8.0 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.6 167685.3_18529001_3 - 1.7e-05 24.9 41.4 8e-05 22.7 2.5 6.5 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 167685.3_18529001_3 - 0.0007 19.8 2.8 0.0007 19.8 2.8 6.7 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 167685.3_18529001_3 - 0.0045 16.8 1.1 0.0045 16.8 1.1 6.0 5 0 0 5 5 5 1 C2H2-type zinc finger Ig_5 PF16681.3 167685.3_18529001_3 - 0.064 13.6 0.6 0.31 11.3 0.6 2.2 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain zf-C2H2_11 PF16622.3 167685.3_18529001_3 - 4.7 6.9 28.3 0.078 12.6 0.7 6.3 6 0 0 6 6 6 0 zinc-finger C2H2-type FOG_N PF15888.3 001272853.2_18527001_3 - 6.2e-38 129.5 0.1 2.3e-37 127.7 0.1 2.0 1 0 0 1 1 1 1 Folded gastrulation N-terminus Annexin PF00191.18 001169333.2_18523001_3 - 2.8e-86 283.5 7.2 1.2e-22 79.5 0.1 4.1 4 0 0 4 4 4 4 Annexin Sigma70_ner PF04546.11 001169333.2_18523001_3 - 0.026 14.3 0.6 3.5 7.3 0.0 2.8 2 1 0 2 2 2 0 Sigma-70, non-essential region Integrin_alpha2 PF08441.10 001169306.2_18529001_1 - 2.2e-98 330.0 0.8 7.3e-98 328.3 0.0 1.9 2 0 0 2 2 2 1 Integrin alpha FG-GAP PF01839.21 001169306.2_18529001_1 - 1.6e-28 98.3 32.6 6.6e-13 48.4 3.3 4.9 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.4 001169306.2_18529001_1 - 1e-06 29.1 18.1 0.00019 21.8 5.1 4.4 2 1 4 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001169306.2_18529001_1 - 0.00015 21.4 0.1 0.00038 20.1 0.1 1.8 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.3 001169306.2_18529001_1 - 0.0072 15.8 0.0 0.0072 15.8 0.0 1.6 2 0 0 2 2 2 1 Lysine-rich CEACAM1 co-isolated protein family 7tm_6 PF02949.18 167283.3_18526001_2 - 2.8e-66 223.6 10.6 3.5e-66 223.3 10.6 1.1 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 167283.3_18526001_3 - 3.8e-55 187.5 24.6 4.8e-55 187.1 24.6 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor Pkinase PF00069.23 080535.3_18529001_1 - 7.5e-59 199.1 0.0 7.5e-59 199.1 0.0 2.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.15 080535.3_18529001_1 - 9.3e-28 97.1 0.0 9.3e-28 97.1 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Rho_Binding PF08912.9 080535.3_18529001_1 - 1.8e-16 60.5 11.2 1.8e-16 60.5 11.2 11.0 5 3 7 12 12 7 1 Rho Binding Kinase-like PF14531.4 080535.3_18529001_1 - 1.3e-09 37.6 0.0 4.7e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Kinase-like PH PF00169.27 080535.3_18529001_1 - 2e-05 24.9 1.3 0.002 18.5 0.0 3.1 3 0 0 3 3 2 1 PH domain C1_1 PF00130.20 080535.3_18529001_1 - 6.5e-05 22.6 6.6 0.00015 21.5 6.6 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ZapB PF06005.10 080535.3_18529001_1 - 0.0044 17.3 10.6 0.0044 17.3 10.6 10.3 5 2 3 8 8 5 1 Cell division protein ZapB C1_2 PF03107.14 080535.3_18529001_1 - 0.063 13.5 2.5 0.26 11.5 2.5 2.1 1 0 0 1 1 1 0 C1 domain Pkinase_C PF00433.22 080535.3_18529001_1 - 0.14 12.8 1.2 0.36 11.4 1.2 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain DUF1447 PF07288.9 080535.3_18529001_1 - 0.28 11.1 5.8 1 9.3 5.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) APH PF01636.21 080535.3_18529001_1 - 5.9 6.6 9.0 0.28 11.0 0.3 3.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family Ion_trans PF00520.29 001201675.1_18529001_2 - 1.7e-243 803.5 91.9 4.7e-70 235.5 11.5 4.2 4 0 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.11 001201675.1_18529001_2 - 4.8e-35 121.5 1.9 4.8e-35 121.5 1.9 2.5 3 0 0 3 3 3 1 Sodium ion transport-associated Na_trans_cytopl PF11933.6 001201675.1_18529001_2 - 1.8e-34 119.4 0.0 5.3e-33 114.6 0.0 2.9 1 1 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel PKD_channel PF08016.10 001201675.1_18529001_2 - 5.7e-13 48.2 81.2 5.6e-05 21.9 6.0 9.5 5 3 3 8 8 8 7 Polycystin cation channel GPHH PF16905.3 001201675.1_18529001_2 - 4.9e-07 29.3 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF2894 PF11445.6 001201675.1_18529001_2 - 2.5 8.4 6.6 41 4.4 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Ion_trans PF00520.29 001201694.1_18529001_2 - 5.6e-243 801.8 92.2 4.7e-70 235.5 11.5 4.2 4 0 0 4 4 4 4 Ion transport protein Na_trans_cytopl PF11933.6 001201694.1_18529001_2 - 7.3e-44 150.1 0.7 2.7e-43 148.2 0.7 1.9 1 1 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.11 001201694.1_18529001_2 - 3.7e-34 118.6 2.1 3.7e-34 118.6 2.1 2.5 3 0 0 3 3 3 1 Sodium ion transport-associated PKD_channel PF08016.10 001201694.1_18529001_2 - 8.8e-13 47.6 81.4 7.9e-05 21.4 6.2 9.5 5 3 3 8 8 8 7 Polycystin cation channel GPHH PF16905.3 001201694.1_18529001_2 - 5e-07 29.3 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF2894 PF11445.6 001201694.1_18529001_2 - 2.9 8.2 6.5 46 4.3 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Ion_trans PF00520.29 001201719.1_18529001_2 - 6.1e-243 801.7 92.2 4.8e-70 235.4 11.5 4.2 4 0 0 4 4 4 4 Ion transport protein Na_trans_cytopl PF11933.6 001201719.1_18529001_2 - 4.1e-51 173.7 0.1 1.6e-50 171.8 0.1 2.0 1 1 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.11 001201719.1_18529001_2 - 6.7e-35 121.0 1.9 6.7e-35 121.0 1.9 2.1 3 0 0 3 3 3 1 Sodium ion transport-associated PKD_channel PF08016.10 001201719.1_18529001_2 - 1.1e-12 47.2 81.5 8e-05 21.4 6.2 9.5 5 3 3 8 8 8 7 Polycystin cation channel GPHH PF16905.3 001201719.1_18529001_2 - 5e-07 29.3 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated UPF0239 PF06783.9 001201719.1_18529001_2 - 0.24 11.5 2.3 0.53 10.4 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) DUF1397 PF07165.9 132889.3_18524001_3 - 7.9e-74 247.4 13.5 1.1e-73 246.9 13.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) Ribosomal_L28e PF01778.15 001298097.1_18524001_1 - 3.5e-35 121.0 1.6 3.5e-35 121.0 1.6 2.1 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.12 001298097.1_18524001_1 - 1.2e-22 80.2 29.0 1.2e-22 80.2 29.0 2.8 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.8 001298097.1_18524001_1 - 0.00085 18.6 27.9 0.0014 18.0 27.9 1.4 1 0 0 1 1 1 1 BUD22 LAP1C PF05609.10 001298097.1_18524001_1 - 0.018 14.1 12.4 0.025 13.6 12.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TFIIF_alpha PF05793.10 001298097.1_18524001_1 - 1.8 6.9 45.2 2.8 6.3 45.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GTP_cyclohydro2 PF00925.18 001298097.1_18524001_3 - 0.1 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II ERM PF00769.17 206667.3_18525001_1 - 1.8e-69 234.1 55.9 1.8e-69 234.1 55.9 2.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.16 206667.3_18525001_1 - 5e-29 101.0 0.4 5e-29 101.0 0.4 3.1 2 1 0 2 2 2 1 FERM central domain FERM_C PF09380.8 206667.3_18525001_1 - 6.4e-26 90.4 0.0 2.3e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.8 206667.3_18525001_1 - 2.3e-12 46.5 1.3 4.1e-12 45.7 0.3 2.0 2 0 0 2 2 2 1 FERM N-terminal domain ACBP PF00887.17 206667.3_18525001_1 - 0.024 14.7 3.8 0.17 12.0 0.1 3.1 3 0 0 3 3 3 0 Acyl CoA binding protein Reo_sigmaC PF04582.10 206667.3_18525001_1 - 0.59 9.3 1.9 1 8.5 1.9 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein MA3 PF02847.15 001272603.1_18527001_2 - 7.7e-56 186.8 0.2 8e-30 103.0 0.3 2.3 2 0 0 2 2 2 2 MA3 domain RHD_DNA_bind PF00554.20 001298290.1_18529001_3 - 9.5e-34 116.6 0.7 9.5e-34 116.6 0.7 4.2 4 0 0 4 4 4 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 001298290.1_18529001_3 - 6.3e-21 74.2 0.4 6.3e-21 74.2 0.4 3.3 3 1 0 3 3 1 1 Rel homology dimerisation domain TIG PF01833.22 001298290.1_18529001_3 - 1.9e-05 24.5 0.2 9.2e-05 22.3 0.1 2.4 2 1 0 2 2 1 1 IPT/TIG domain Suf PF05843.12 001298290.1_18529001_3 - 0.00049 20.0 23.7 0.071 12.9 6.8 2.9 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) MecA PF05389.10 001298290.1_18529001_3 - 0.00079 19.0 12.6 0.11 12.0 2.3 2.4 2 0 0 2 2 2 2 Negative regulator of genetic competence (MecA) TERB2 PF15101.4 001298290.1_18529001_3 - 0.0014 18.6 26.6 0.055 13.4 6.4 2.7 2 0 0 2 2 2 2 Telomere-associated protein TERB2 MAT1 PF06391.11 001298290.1_18529001_3 - 0.0015 18.3 7.4 0.0015 18.3 7.4 2.7 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 CD20 PF04103.13 001298290.1_18529001_3 - 0.0015 18.5 0.2 0.0015 18.5 0.2 2.8 2 0 0 2 2 2 1 CD20-like family DUF3824 PF12868.5 001298290.1_18529001_3 - 0.0025 18.3 2.5 0.0025 18.3 2.5 4.3 4 0 0 4 4 3 1 Domain of unknwon function (DUF3824) FHIPEP PF00771.18 001298290.1_18529001_3 - 0.01 14.2 15.7 0.1 10.9 3.7 2.2 2 0 0 2 2 2 0 FHIPEP family Peptidase_S49_N PF08496.8 001298290.1_18529001_3 - 0.027 14.4 16.4 0.57 10.1 5.7 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.10 001298290.1_18529001_3 - 0.62 9.7 18.5 1.1 8.9 3.2 2.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.4 001298290.1_18529001_3 - 0.73 9.4 15.3 2.1 7.9 3.3 2.6 2 0 0 2 2 2 0 FAM176 family RLL PF10036.7 001298290.1_18529001_3 - 0.81 9.4 26.2 1.7 8.3 8.5 2.6 2 0 0 2 2 2 0 Putative carnitine deficiency-associated protein RAB3GAP2_N PF14655.4 001298290.1_18529001_3 - 1.2 8.1 21.3 2.1 7.3 4.9 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2052 PF09747.7 001298290.1_18529001_3 - 2.7 8.0 21.2 7.1 6.6 6.3 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PTPRCAP PF15713.3 001298290.1_18529001_3 - 3.2 7.9 20.8 4.8 7.3 4.1 2.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF2232 PF09991.7 001298290.1_18529001_3 - 3.3 6.7 13.1 6.2 5.8 3.6 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) FAM91_C PF14648.4 001298290.1_18529001_3 - 3.3 6.3 16.4 0.62 8.7 4.8 2.4 2 0 0 2 2 2 0 FAM91 C-terminus Exonuc_VII_L PF02601.13 001298290.1_18529001_3 - 4.1 6.8 29.9 0.26 10.7 8.9 2.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Velvet PF11754.6 001298290.1_18529001_3 - 4.1 7.1 24.2 0.86 9.4 2.5 3.4 3 0 0 3 3 3 0 Velvet factor Rxt3 PF08642.8 001298290.1_18529001_3 - 5 7.8 16.0 5 7.8 3.1 3.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF4175 PF13779.4 001298290.1_18529001_3 - 6 4.5 50.3 0.75 7.5 17.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4175) CPSF100_C PF13299.4 001298290.1_18529001_3 - 6.4 6.8 25.6 11 6.1 9.3 2.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TFB6 PF17110.3 001298290.1_18529001_3 - 6.5 6.3 12.9 9.6 5.8 3.3 2.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH GET2 PF08690.8 001298290.1_18529001_3 - 6.9 6.1 25.8 8.4 5.8 10.1 2.8 2 0 0 2 2 2 0 GET complex subunit GET2 IncA PF04156.12 001298290.1_18529001_3 - 7.7 6.1 31.5 6.4 6.4 11.3 2.5 2 0 0 2 2 2 0 IncA protein EIIBC-GUT_N PF03612.12 001298290.1_18529001_3 - 9.3 5.8 27.0 11 5.6 7.5 2.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4746 PF15928.3 001298290.1_18529001_3 - 9.4 5.4 17.3 0.32 10.2 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF4407 PF14362.4 001298290.1_18529001_3 - 9.7 5.3 29.9 3.8 6.6 9.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Helicase_C_2 PF13307.4 130542.4_18526001_1 - 5.7e-53 179.4 0.0 1.4e-52 178.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.13 130542.4_18526001_1 - 1e-52 178.2 0.0 2.9e-52 176.7 0.0 1.8 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.13 130542.4_18526001_1 - 5.9e-05 23.0 0.8 0.084 12.7 0.3 2.7 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.27 130542.4_18526001_1 - 0.0056 16.3 1.8 0.018 14.7 0.1 2.7 3 1 0 3 3 3 1 DEAD/DEAH box helicase DUF913 PF06025.10 130542.4_18526001_1 - 0.0089 14.9 1.1 0.66 8.7 0.0 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF913) PhoH PF02562.14 130542.4_18526001_1 - 0.052 12.9 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein CCDC-167 PF15188.4 130542.4_18526001_1 - 0.21 11.8 15.4 3.2 8.0 7.2 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DAG_kinase_N PF14513.4 130542.4_18526001_1 - 0.42 10.7 3.5 3.6 7.6 0.3 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Mnd1 PF03962.13 130542.4_18526001_1 - 6 6.6 13.8 3.5 7.3 5.5 2.7 2 0 0 2 2 2 0 Mnd1 family PAP_assoc PF03828.17 206602.2_18523001_1 - 2.8e-10 40.1 0.0 5.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Fam20C PF06702.10 206602.2_18523001_1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 BTB PF00651.29 001272205.1_18529001_1 - 1.6e-25 89.3 0.3 2.8e-25 88.6 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.4 001272205.1_18529001_1 - 1.7e-05 24.5 8.8 0.00011 22.0 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.24 001272205.1_18529001_1 - 0.0011 19.1 11.2 0.057 13.8 2.2 3.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.5 001272205.1_18529001_1 - 0.11 12.7 6.6 6.7 7.1 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001272205.1_18529001_1 - 0.29 11.4 6.3 1 9.7 1.0 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.19 001272205.1_18529001_1 - 0.52 10.3 2.9 1.3 9.1 2.9 1.6 1 0 0 1 1 1 0 FYVE zinc finger Arm PF00514.21 001272220.1_18527001_2 - 3.4e-45 150.7 24.0 3e-08 33.3 0.1 10.8 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.18 001272220.1_18527001_2 - 2.4e-08 32.9 9.2 2.1e-07 29.7 2.8 3.2 2 1 1 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.5 001272220.1_18527001_2 - 4.4e-07 29.9 6.0 0.0019 18.1 0.8 4.2 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.4 001272220.1_18527001_2 - 8.1e-07 29.2 6.9 0.0015 18.7 0.8 4.6 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.4 001272220.1_18527001_2 - 3.5e-05 24.0 5.3 3.2 8.2 0.1 5.1 3 1 1 4 4 4 2 HEAT-like repeat KAP PF05804.10 001272220.1_18527001_2 - 9.1e-05 20.7 2.9 0.021 12.8 0.6 2.9 3 0 0 3 3 3 2 Kinesin-associated protein (KAP) HEAT PF02985.20 001272220.1_18527001_2 - 0.00033 20.5 4.5 1 9.7 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat DUF3361 PF11841.6 001272220.1_18527001_2 - 0.00039 20.3 3.6 1.5 8.6 0.0 4.6 2 1 3 5 5 5 1 Domain of unknown function (DUF3361) Arm_2 PF04826.11 001272220.1_18527001_2 - 0.0045 16.3 9.3 0.13 11.5 0.1 3.6 3 1 1 4 4 4 2 Armadillo-like Atx10homo_assoc PF09759.7 001272220.1_18527001_2 - 0.0053 16.7 1.9 0.084 12.8 0.1 3.3 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.6 001272220.1_18527001_2 - 2.9 7.9 4.4 1.6e+02 2.3 0.6 4.1 3 1 3 6 6 6 0 V-ATPase subunit H RasGEF_N_2 PF14663.4 001272220.1_18527001_2 - 3.3 8.0 4.9 17 5.7 0.3 3.9 3 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain N2227 PF07942.10 001272225.1_18524001_1 - 3.7e-107 357.4 0.0 5.1e-107 357.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.10 001272225.1_18524001_1 - 0.13 12.8 0.0 0.39 11.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.4 132503.3_18525001_2 - 1.4e-18 65.9 82.5 0.0029 18.2 0.3 11.2 11 0 0 11 11 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.4 132503.3_18525001_2 - 6.6e-18 64.1 47.0 1.2e-05 25.4 4.6 9.5 9 0 0 9 9 9 5 Zinc-finger double domain zf-AD PF07776.13 132503.3_18525001_2 - 4.8e-13 49.0 1.8 4.8e-13 49.0 1.8 4.7 4 1 1 5 5 5 1 Zinc-finger associated domain (zf-AD) zf-C2H2 PF00096.24 132503.3_18525001_2 - 6.3e-13 48.3 72.3 0.0028 17.9 1.4 10.4 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 132503.3_18525001_2 - 1.9e-11 43.8 42.2 0.18 12.0 0.2 9.5 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.10 132503.3_18525001_2 - 5e-08 33.0 41.4 0.0036 17.4 2.3 7.3 4 1 5 9 9 8 6 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.5 132503.3_18525001_2 - 1.9e-07 31.1 43.5 0.27 11.5 0.6 9.1 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 132503.3_18525001_2 - 0.002 17.9 52.3 0.0069 16.2 0.2 8.8 8 0 0 8 8 8 4 C2H2-type zinc finger zinc_ribbon_15 PF17032.3 132503.3_18525001_2 - 0.01 16.4 32.3 3.2 8.4 0.3 6.0 4 1 0 5 5 5 0 zinc-ribbon family Mso1_Sec1_bdg PF14475.4 132503.3_18525001_2 - 1.1 8.8 3.3 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Sec1-binding region of Mso1 AT_hook PF02178.17 132503.3_18525001_2 - 2.9 8.0 16.5 0.085 12.7 3.2 2.9 2 0 0 2 2 2 0 AT hook motif GAGA PF09237.9 132503.3_18525001_2 - 5.6 6.7 12.2 8.9 6.1 0.1 5.0 5 1 1 6 6 6 0 GAGA factor Spt5_N PF11942.6 132503.3_18525001_2 - 8.1 7.4 19.1 2.1 9.2 3.6 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RabGAP-TBC PF00566.16 001169251.4_18529001_3 - 1e-50 172.3 0.4 1e-50 172.3 0.4 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain LOH1CR12 PF10158.7 132531.2_18523001_3 - 4.7e-59 198.0 0.9 6.4e-59 197.6 0.9 1.2 1 0 0 1 1 1 1 Tumour suppressor protein DUF1664 PF07889.10 132531.2_18523001_3 - 0.029 14.2 0.2 0.049 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF725 PF05267.10 132306.3_18522001_2 - 4e-12 46.1 5.8 7.6e-12 45.2 5.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF725) PNP_UDP_1 PF01048.18 001169238.2_18526001_3 - 4.2e-06 26.0 0.0 1.2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily MqsR_toxin PF15723.3 001169238.2_18526001_3 - 0.052 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA AAT PF03417.14 132315.1_18524001_1 - 3e-73 246.1 0.3 4.6e-73 245.5 0.3 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Homeobox PF00046.27 001272417.1_18529001_2 - 4.5e-21 74.3 1.4 1.3e-20 72.9 1.4 1.8 1 0 0 1 1 1 1 Homeobox domain SKG6 PF08693.8 001272417.1_18529001_2 - 1.4 8.2 6.1 4 6.8 6.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NHL PF01436.19 001298110.1_18529001_1 - 4.4e-24 83.1 23.6 2.3e-07 30.4 0.2 6.9 7 0 0 7 7 7 4 NHL repeat zf-B_box PF00643.22 001298110.1_18529001_1 - 6.6e-08 32.5 28.9 1.2e-07 31.6 9.0 5.5 5 1 0 5 5 5 2 B-box zinc finger zf-C3HC4_2 PF13923.4 001298110.1_18529001_1 - 0.00027 20.6 3.5 0.00027 20.6 3.5 5.1 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001298110.1_18529001_1 - 0.0011 18.8 3.3 0.0011 18.8 3.3 4.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001298110.1_18529001_1 - 0.0015 18.2 4.1 0.0015 18.2 4.1 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001298110.1_18529001_1 - 0.0036 17.0 2.6 0.0036 17.0 2.6 5.0 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 Pex14_N PF04695.11 001298110.1_18529001_1 - 2.4 8.8 50.9 0.017 15.7 12.3 3.8 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PHD PF00628.27 001272789.1_18529001_3 - 1.2e-13 50.6 24.6 1.6e-06 27.8 12.7 2.9 1 1 1 2 2 2 2 PHD-finger PHD_4 PF16866.3 001272789.1_18529001_3 - 4.4 7.3 19.7 0.025 14.6 7.5 3.1 1 1 1 2 2 2 0 PHD-finger zf-H2C2_2 PF13465.4 078545.3_18526001_3 - 4.8e-09 36.1 9.8 8.3e-06 25.9 1.7 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.24 078545.3_18526001_3 - 1.1e-07 31.8 33.4 0.00014 22.0 3.9 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 078545.3_18526001_3 - 0.00043 20.7 3.5 0.00043 20.7 3.5 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.4 078545.3_18526001_3 - 0.01 15.6 2.8 0.01 15.6 2.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.5 078545.3_18526001_3 - 0.06 13.6 12.0 0.88 9.9 2.3 4.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-LYAR PF08790.9 078545.3_18526001_3 - 0.25 11.2 2.1 2.8 7.8 0.0 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Rtf2 PF04641.10 078545.3_18526001_3 - 2.5 7.3 24.7 0.069 12.4 0.3 3.2 3 0 0 3 3 3 0 Rtf2 RING-finger zf-C2HC_2 PF13913.4 078545.3_18526001_3 - 5.8 6.8 14.1 0.34 10.8 0.8 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.8 078545.3_18526001_3 - 7.9 6.6 7.7 2 8.4 1.0 2.8 3 0 0 3 3 3 0 Zinc ribbon domain Lig_chan PF00060.24 132178.1_18524001_1 - 0.0077 15.9 0.0 0.037 13.7 0.0 2.1 1 1 0 1 1 1 1 Ligand-gated ion channel DUF819 PF05684.10 132178.1_18524001_1 - 0.038 12.9 1.9 0.069 12.1 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF819) Adipogenin PF15202.4 132178.1_18524001_1 - 6.3 6.8 9.1 0.22 11.4 1.4 2.4 2 0 0 2 2 2 0 Adipogenin BACK PF07707.13 001297928.1_18524001_1 - 2.8e-20 72.2 0.0 6.4e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF4734 PF15881.3 001297928.1_18524001_1 - 0.00044 20.2 0.3 0.0011 19.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4734) Tantalus PF15386.4 001297928.1_18524001_1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Drosophila Tantalus-like TMF_DNA_bd PF12329.6 134511.2_18526001_2 - 0.0011 18.8 10.7 0.0011 18.8 10.7 4.3 2 1 2 4 4 4 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.10 134511.2_18526001_2 - 0.0017 17.7 5.5 0.0017 17.7 5.5 2.5 1 1 1 3 3 3 1 Reovirus sigma C capsid protein FliJ PF02050.14 134511.2_18526001_2 - 0.012 15.7 34.4 0.39 10.8 1.0 3.4 1 1 1 3 3 3 0 Flagellar FliJ protein ATG16 PF08614.9 134511.2_18526001_2 - 0.017 15.1 42.5 0.092 12.8 21.3 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) IncA PF04156.12 134511.2_18526001_2 - 4.4 6.9 44.2 2.3 7.8 30.6 2.8 1 1 1 2 2 2 0 IncA protein DUF4201 PF13870.4 134511.2_18526001_2 - 5.6 6.5 38.7 1.7 8.1 26.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Phage_GP20 PF06810.9 134511.2_18526001_2 - 8.9 6.0 28.2 2.8 7.6 6.1 3.7 1 1 2 3 3 3 0 Phage minor structural protein GP20 MscS_porin PF12795.5 134511.2_18526001_2 - 9.8 5.5 41.6 3.8 6.8 17.1 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain BUD22 PF09073.8 001272721.1_18526001_2 - 0.64 9.2 9.4 1 8.5 9.4 1.3 1 0 0 1 1 1 0 BUD22 HLH PF00010.24 001169182.3_18529001_2 - 9.6e-11 41.4 0.4 3.8e-10 39.4 0.4 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SlyX PF04102.10 001169182.3_18529001_2 - 0.48 10.9 7.8 0.05 14.1 0.7 2.6 2 0 0 2 2 2 0 SlyX adh_short PF00106.23 130479.3_18524001_3 - 2.1e-16 59.9 0.0 3.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 130479.3_18524001_3 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 130479.3_18524001_3 - 0.00016 21.5 0.1 0.00036 20.3 0.0 1.5 2 0 0 2 2 2 1 KR domain Sel1 PF08238.10 001042859.2_18522001_1 - 4.6e-07 30.2 0.4 9.7e-05 22.8 0.3 2.5 2 0 0 2 2 2 2 Sel1 repeat TPR_8 PF13181.4 001042859.2_18522001_1 - 0.0045 17.0 0.8 2.8 8.3 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.15 001042859.2_18522001_1 - 6.9 6.9 6.3 10 6.4 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat PsbJ PF01788.15 167641.2_18525001_2 - 0.0015 18.3 1.3 0.004 16.9 1.3 1.8 1 0 0 1 1 1 1 PsbJ DSPc PF00782.18 134488.2_18525001_1 - 1.2e-26 92.9 0.0 1.8e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 134488.2_18525001_1 - 0.017 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.12 134488.2_18525001_1 - 0.024 14.7 0.5 0.23 11.5 0.5 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Acyl_transf_3 PF01757.20 134478.2_18525001_1 - 3.3e-20 72.3 42.0 7.1e-20 71.2 42.0 1.5 1 0 0 1 1 1 1 Acyltransferase family Zip PF02535.20 130678.3_18522001_1 - 9 5.3 12.9 12 4.9 12.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3295 PF11702.6 130678.3_18522001_2 - 0.0055 16.0 32.7 0.0065 15.8 32.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF4407 PF14362.4 130678.3_18522001_2 - 0.032 13.5 4.3 0.043 13.0 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hamartin PF04388.10 130678.3_18522001_2 - 0.32 9.4 32.0 0.4 9.1 32.0 1.0 1 0 0 1 1 1 0 Hamartin protein PRCC PF10253.7 130678.3_18522001_2 - 0.7 10.5 27.1 1.4 9.5 27.1 1.4 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Endomucin PF07010.10 130678.3_18522001_2 - 0.98 9.2 44.2 1.4 8.7 44.2 1.2 1 0 0 1 1 1 0 Endomucin GvpL_GvpF PF06386.9 130678.3_18522001_2 - 1.2 8.9 5.3 1.7 8.3 5.3 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PGA2 PF07543.10 130678.3_18522001_2 - 2.8 7.8 14.4 0.23 11.3 9.4 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 SRP-alpha_N PF04086.11 130678.3_18522001_2 - 4.9 6.8 30.3 7.3 6.3 30.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF334 PF03904.11 130678.3_18522001_2 - 7.6 5.9 10.6 15 4.9 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) CLN3 PF02487.15 130678.3_18522001_2 - 7.7 5.3 9.9 4.2 6.2 1.3 2.1 2 0 0 2 2 2 0 CLN3 protein Mucin PF01456.15 130687.3_18523001_1 - 0.00096 19.0 22.5 0.002 18.0 22.5 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein zf-AD PF07776.13 001272359.2_18529001_3 - 2.2e-10 40.5 1.9 2.2e-10 40.5 1.9 2.5 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) HTH_23 PF13384.4 001272359.2_18529001_3 - 1.6e-06 27.6 0.2 0.0054 16.4 0.0 2.7 2 0 0 2 2 2 2 Homeodomain-like domain SR-25 PF10500.7 001272359.2_18529001_3 - 0.0029 17.1 7.0 0.0029 17.1 7.0 4.8 4 1 0 5 5 5 1 Nuclear RNA-splicing-associated protein zf-C2H2_6 PF13912.4 001272359.2_18529001_3 - 0.0075 16.1 1.0 0.0075 16.1 1.0 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.24 001272359.2_18529001_3 - 0.017 15.4 19.2 0.49 10.8 2.7 4.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001272359.2_18529001_3 - 0.018 15.3 0.3 0.018 15.3 0.3 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.10 001272359.2_18529001_3 - 0.02 15.1 0.9 0.02 15.1 0.9 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.4 001272359.2_18529001_3 - 0.021 15.5 1.4 0.021 15.5 1.4 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger HTH_7 PF02796.13 001272359.2_18529001_3 - 0.023 14.7 0.4 1.2 9.2 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_11 PF08279.10 001272359.2_18529001_3 - 0.078 12.8 0.8 7.1 6.5 0.0 2.7 2 0 0 2 2 2 0 HTH domain PDZ PF00595.22 001297991.1_18528001_3 - 1.8e-63 210.7 5.7 2.3e-12 46.9 0.5 7.3 7 0 0 7 7 7 7 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001297991.1_18528001_3 - 1.5e-32 111.6 0.4 2e-06 27.9 0.0 7.2 7 0 0 7 7 7 6 PDZ domain Tricorn_PDZ PF14685.4 001297991.1_18528001_3 - 0.0014 18.5 0.7 2.5 8.0 0.0 4.4 5 0 0 5 5 5 2 Tricorn protease PDZ domain FH2 PF02181.21 001272197.1_18529001_2 - 2.3e-114 382.3 2.0 2.3e-114 382.3 2.0 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.14 001272197.1_18529001_2 - 7.6e-63 211.5 0.8 7.6e-63 211.5 0.8 2.8 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.11 001272197.1_18529001_2 - 5.9e-40 136.7 0.0 4.6e-39 133.8 0.0 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Fez1 PF06818.13 001272197.1_18529001_2 - 1.9 8.8 20.0 1.3 9.3 14.7 2.7 2 0 0 2 2 2 0 Fez1 PPR PF01535.18 130557.3_18527001_3 - 1e-09 37.8 3.3 0.075 13.2 0.1 5.5 6 0 0 6 6 6 3 PPR repeat PPR_2 PF13041.4 130557.3_18527001_3 - 1.8e-08 34.3 0.0 0.076 13.1 0.0 5.4 4 1 2 6 6 6 2 PPR repeat family PPR_3 PF13812.4 130557.3_18527001_3 - 0.00027 20.8 0.0 0.37 10.8 0.0 4.3 4 1 1 5 5 5 1 Pentatricopeptide repeat domain PPR_long PF17177.2 130557.3_18527001_3 - 0.00097 18.4 2.7 0.25 10.6 0.0 3.8 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PROPR PPR_1 PF12854.5 130557.3_18527001_3 - 0.059 13.0 3.1 8.4 6.1 0.1 4.2 5 0 0 5 5 5 0 PPR repeat Clathrin PF00637.18 130557.3_18527001_3 - 0.078 12.7 2.5 58 3.4 0.0 4.7 5 1 0 5 5 5 0 Region in Clathrin and VPS TPR_14 PF13428.4 130557.3_18527001_3 - 0.1 13.3 23.4 12 6.8 0.2 9.1 8 0 0 8 8 8 0 Tetratricopeptide repeat RFC1 PF08519.10 130557.3_18527001_3 - 0.26 11.3 1.3 0.79 9.7 0.2 2.4 2 1 0 2 2 2 0 Replication factor RFC1 C terminal domain TPR_7 PF13176.4 130557.3_18527001_3 - 0.53 10.3 3.6 1 9.4 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.4 130557.3_18527001_3 - 1.3 9.4 31.4 1.7 9.1 0.2 7.6 8 1 2 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.4 130557.3_18527001_3 - 6.3 7.5 15.8 73 4.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Adap_comp_sub PF00928.19 143755.4_18525001_2 - 2.8e-21 76.0 0.0 4.1e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.18 143755.4_18525001_2 - 4e-08 33.2 1.0 6.5e-08 32.5 1.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Prefoldin_2 PF01920.18 132341.3_18522001_3 - 0.059 13.2 3.6 4.4 7.2 2.0 3.0 2 1 0 2 2 2 0 Prefoldin subunit TACC PF05010.12 132341.3_18522001_3 - 0.076 12.7 1.1 0.16 11.6 0.1 1.7 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) RNA_pol_A_CTD PF03118.13 132341.3_18522001_3 - 0.077 12.6 0.4 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Mnd1 PF03962.13 132341.3_18522001_3 - 0.5 10.1 3.0 5.7 6.6 0.4 2.1 2 0 0 2 2 2 0 Mnd1 family ADIP PF11559.6 132341.3_18522001_3 - 0.52 10.3 7.1 6.7 6.6 0.8 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4600 PF15372.4 132341.3_18522001_3 - 0.6 10.4 4.1 12 6.2 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Sec34 PF04136.13 132341.3_18522001_3 - 0.8 9.5 7.4 0.73 9.6 0.5 2.8 2 1 1 3 3 3 0 Sec34-like family BLOC1_2 PF10046.7 132341.3_18522001_3 - 0.98 9.6 3.8 11 6.3 0.0 2.9 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spt20 PF12090.6 001298102.1_18526001_1 - 10 5.5 16.5 19 4.6 16.5 1.4 1 0 0 1 1 1 0 Spt20 family Fez1 PF06818.13 001298102.1_18526001_2 - 3.1e-17 63.6 102.3 4.4e-16 59.8 58.4 4.4 2 1 1 3 3 3 1 Fez1 Presenilin PF01080.15 001298102.1_18526001_2 - 0.77 8.3 55.6 1.4 7.5 30.6 2.5 2 0 0 2 2 2 0 Presenilin DUF1510 PF07423.9 001298102.1_18526001_2 - 1.7 7.9 45.5 2.4 7.4 6.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) VID27 PF08553.8 001298102.1_18526001_2 - 9.5 4.5 39.0 0.69 8.3 21.5 2.3 2 0 0 2 2 2 0 VID27 cytoplasmic protein zf-AD PF07776.13 080265.3_18522001_2 - 1.8e-12 47.2 1.2 1.8e-12 47.2 1.2 2.1 1 1 0 2 2 2 1 Zinc-finger associated domain (zf-AD) PBP_GOBP PF01395.20 134548.2_18522001_2 - 8.4e-15 54.8 1.9 1.5e-14 54.0 1.9 1.4 1 0 0 1 1 1 1 PBP/GOBP family LysM PF01476.18 001144684.2_18522001_3 - 0.0002 21.3 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 LysM domain DUF1487 PF07368.9 132628.3_18523001_1 - 4.5e-92 307.2 0.0 5.7e-92 306.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) SPX PF03105.17 001297962.1_18526001_3 - 0.00046 20.1 6.2 0.00046 20.1 6.2 2.5 3 0 0 3 3 3 2 SPX domain SR-25 PF10500.7 001297962.1_18526001_3 - 0.0035 16.9 48.9 0.0035 16.9 48.9 4.3 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein Apt1 PF10351.7 001297962.1_18526001_3 - 0.015 14.0 31.8 0.023 13.4 9.1 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Macoilin PF09726.7 001297962.1_18526001_3 - 2.3 6.5 44.7 0.22 9.9 15.8 2.3 2 0 0 2 2 2 0 Transmembrane protein DUF1168 PF06658.10 001297962.1_18526001_3 - 2.4 7.8 47.4 0.27 10.9 6.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1168) Mem_trans PF03547.16 001297962.1_18526001_3 - 4.5 5.4 9.7 0.48 8.6 0.1 2.1 2 0 0 2 2 2 0 Membrane transport protein DUF4692 PF15763.3 001297962.1_18526001_3 - 5.9 7.2 33.6 0.017 15.5 8.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4692) SPX PF03105.17 131995.2_18524001_2 - 0.00021 21.2 6.1 0.00021 21.2 6.1 2.7 3 0 0 3 3 3 2 SPX domain SR-25 PF10500.7 131995.2_18524001_2 - 0.002 17.6 48.9 0.002 17.6 48.9 4.4 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein DUF4692 PF15763.3 131995.2_18524001_2 - 0.0097 16.3 8.9 0.0097 16.3 8.9 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4692) SAPS PF04499.13 131995.2_18524001_2 - 5.9 5.4 23.0 5.9 5.4 0.8 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein LIN52 PF10044.7 132028.3_18522001_3 - 1e-31 109.4 0.4 1.6e-31 108.7 0.1 1.5 2 0 0 2 2 2 1 Retinal tissue protein 7TM_GPCR_Srw PF10324.7 001297964.1_18527001_2 - 5.3e-23 81.7 23.6 7.2e-23 81.2 23.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.19 001297964.1_18527001_2 - 5.4e-17 61.8 21.0 8.5e-17 61.1 21.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cyclin_N PF00134.21 130624.3_18524001_3 - 2.7e-13 49.7 0.2 3.1e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.17 130624.3_18524001_3 - 2.3e-05 24.3 0.4 0.00038 20.4 0.0 2.7 3 0 0 3 3 3 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.3 130624.3_18524001_3 - 3.2e-05 24.1 0.0 0.00025 21.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain TFIIB PF00382.17 130624.3_18524001_3 - 0.0083 16.0 0.6 3.6 7.6 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat E2F_TDP PF02319.18 130624.3_18524001_3 - 0.04 13.8 0.1 8 6.4 0.0 2.6 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Ribosomal_60s PF00428.17 130624.3_18524001_3 - 0.15 12.5 0.5 0.31 11.5 0.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein SOG2 PF10428.7 130624.3_18524001_3 - 0.82 8.7 23.8 1.4 7.9 23.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein ORC6 PF05460.11 130624.3_18524001_3 - 8 5.5 25.4 6.8 5.7 0.0 2.9 3 0 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) Innexin PF00876.16 132146.2_18524001_3 - 3e-91 306.2 18.8 4.3e-91 305.7 18.8 1.2 1 0 0 1 1 1 1 Innexin Suf PF05843.12 001111009.4_18526001_3 - 5.4e-90 302.2 1.7 1.3e-86 291.2 0.0 4.3 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.8 001111009.4_18526001_3 - 0.0008 18.5 8.9 2.5 7.0 0.0 5.3 2 1 2 5 5 5 2 NRDE-2, necessary for RNA interference dsrm PF00035.24 001169346.2_18527001_2 - 4.3e-08 33.6 0.0 8.2e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Mod_r PF07200.11 001272171.1_18523001_1 - 2.3e-22 79.6 2.0 3e-22 79.2 2.0 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein zf-C2H2 PF00096.24 166852.3_18525001_2 - 3.3e-10 39.7 76.5 0.0012 19.1 3.8 10.0 10 0 0 10 10 10 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 166852.3_18525001_2 - 1.4e-06 28.5 76.5 0.094 13.5 1.8 9.8 10 0 0 10 10 10 6 C2H2-type zinc finger zf-H2C2_2 PF13465.4 166852.3_18525001_2 - 0.0058 16.9 2.1 0.0058 16.9 2.1 8.1 8 0 0 8 8 8 5 Zinc-finger double domain zf-met PF12874.5 166852.3_18525001_2 - 0.023 14.9 2.0 0.023 14.9 2.0 5.9 7 0 0 7 7 7 0 Zinc-finger of C2H2 type FOXP-CC PF16159.3 166852.3_18525001_2 - 4.3 7.9 45.2 3.1 8.4 0.0 8.7 6 2 3 9 9 9 0 FOXP coiled-coil domain SAM_1 PF00536.28 001297873.1_18529001_3 - 5.8e-15 55.4 0.0 1.2e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 001297873.1_18529001_3 - 6.6e-11 42.0 0.0 2e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Laminin_N PF00055.15 001298314.1_18527001_1 - 1.7e-66 224.0 0.0 1.7e-66 224.0 0.0 2.7 2 1 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.22 001298314.1_18527001_1 - 1.2e-21 76.4 75.8 2.6e-09 36.9 13.6 5.3 5 0 0 5 5 5 3 Laminin EGF domain NTR PF01759.19 001298314.1_18527001_1 - 2.9e-16 59.1 0.1 3e-12 46.2 0.0 2.8 2 1 0 2 2 2 2 UNC-6/NTR/C345C module PT PF04886.10 001169303.2_18529001_1 - 0.00026 20.3 4.2 0.00026 20.3 4.2 1.8 2 0 0 2 2 2 1 PT repeat Peptidase_S8 PF00082.20 001169303.2_18529001_2 - 4.1e-48 164.0 1.2 8.4e-48 163.0 1.2 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.18 001169303.2_18529001_2 - 1.8e-25 88.7 0.0 3.7e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.3 001169303.2_18529001_2 - 9.2e-24 84.0 3.1 1.8e-23 83.0 3.1 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain GF_recep_IV PF14843.4 001169303.2_18529001_2 - 4.3e-21 74.9 174.0 4.6e-14 52.2 29.6 6.2 1 1 4 5 5 5 3 Growth factor receptor domain IV Furin-like_2 PF15913.3 001169303.2_18529001_2 - 7.8e-08 32.3 64.8 1.2e-05 25.3 17.5 8.0 1 1 7 8 8 8 5 Furin-like repeat, cysteine-rich Furin-like PF00757.18 001169303.2_18529001_2 - 1.4e-07 31.4 27.0 1.4e-07 31.4 27.0 6.4 1 1 5 6 6 6 3 Furin-like cysteine rich region VSP PF03302.11 001169303.2_18529001_2 - 3.4e-05 22.8 156.5 0.009 14.8 32.9 9.7 1 1 8 9 9 9 6 Giardia variant-specific surface protein PT PF04886.10 001169303.2_18529001_2 - 0.072 12.5 11.5 0.038 13.4 8.3 2.3 2 0 0 2 2 2 0 PT repeat DUF4149 PF13664.4 001272825.1_18523001_1 - 1.9e-21 76.1 5.8 1.9e-21 76.1 5.8 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) Neur_chan_LBD PF02931.21 001298507.1_18529001_1 - 4.8e-71 238.5 0.0 7.3e-71 237.9 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001298507.1_18529001_1 - 1.6e-57 195.2 0.0 2.7e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3915 PF13054.4 206773.2_18529001_2 - 2.5 8.0 37.6 0.02 14.7 7.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) DUF3915 PF13054.4 001298452.1_18529001_1 - 3.5 7.5 37.6 0.025 14.4 7.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) zf-C2HE PF16278.3 001272669.1_18529001_1 - 0.029 14.7 0.6 0.029 14.7 0.6 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.24 001272669.1_18529001_1 - 0.057 13.8 26.1 0.41 11.1 0.7 5.4 4 1 0 4 4 4 0 Zinc finger, C2H2 type Serglycin PF04360.10 001272669.1_18529001_1 - 0.33 10.7 19.1 0.66 9.8 9.7 3.7 3 0 0 3 3 3 0 Serglycin Band_7 PF01145.23 001169288.1_18525001_3 - 3.1e-08 33.7 0.1 3.1e-08 33.7 0.1 2.2 2 0 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.3 001169288.1_18525001_3 - 1.4e-06 28.4 6.4 1.4e-06 28.4 6.4 3.2 2 2 1 3 3 3 2 Flotillin TFIIA PF03153.11 001272592.1_18529001_1 - 0.00058 19.8 16.9 0.0014 18.5 16.9 1.6 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PIG-Y PF15159.4 001272592.1_18529001_1 - 0.046 14.4 0.5 0.11 13.2 0.5 1.6 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Iron_permease PF04120.10 001272592.1_18529001_1 - 2.9 7.6 15.0 5.6 6.6 15.0 1.4 1 0 0 1 1 1 0 Low affinity iron permease DUF4746 PF15928.3 001272592.1_18529001_1 - 3.9 6.7 11.3 6.4 6.0 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sulfotransfer_3 PF13469.4 001272592.1_18529001_3 - 8e-55 186.4 0.0 1.6e-54 185.5 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.25 001272592.1_18529001_3 - 9.2e-10 38.3 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain SNARE_assoc PF09335.9 001298157.1_18525001_1 - 2e-07 31.4 1.2 5.7e-07 29.9 0.2 2.2 2 1 0 2 2 2 1 SNARE associated Golgi protein PX PF00787.22 001297977.1_18528001_2 - 5.1e-20 71.4 0.0 1.3e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 PX domain RA PF00788.21 001297977.1_18528001_2 - 2.6e-13 50.3 0.3 6.5e-13 49.0 0.3 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.8 001297977.1_18528001_2 - 0.0029 17.4 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain zf-C2H2 PF00096.24 206628.2_18529001_2 - 1.2e-13 50.5 63.0 0.00034 20.8 1.0 9.6 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 206628.2_18529001_2 - 2.9e-12 46.3 39.1 0.00013 22.1 2.0 7.3 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.4 206628.2_18529001_2 - 1.7e-07 30.9 38.0 0.004 16.9 0.3 7.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.5 206628.2_18529001_2 - 0.0035 17.6 35.0 0.33 11.2 2.3 7.0 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.4 206628.2_18529001_2 - 0.067 13.9 0.2 0.051 14.3 2.5 10.2 11 0 0 11 11 11 0 C2H2-type zinc finger I-set PF07679.14 001272289.1_18529001_3 - 1.3e-36 124.4 0.1 1.1e-11 44.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.4 001272289.1_18529001_3 - 7.4e-35 119.3 0.5 3.3e-12 46.7 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.23 001272289.1_18529001_3 - 5.7e-29 100.0 0.2 4.9e-08 32.9 0.1 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001272289.1_18529001_3 - 5.1e-17 61.9 0.2 1.6e-06 28.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001272289.1_18529001_3 - 1.8e-15 56.9 0.3 2.8e-07 30.5 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin V-set domain Band_7 PF01145.23 001298499.1_18525001_1 - 2.6e-32 112.2 0.0 2.6e-32 112.2 0.0 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.4 001298499.1_18525001_1 - 0.0024 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family TFIIA PF03153.11 001298499.1_18525001_1 - 0.34 10.7 14.7 0.5 10.2 14.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.1 001298499.1_18525001_1 - 0.49 10.5 5.2 0.99 9.5 5.2 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SUIM_assoc PF16619.3 001298499.1_18525001_1 - 2 8.4 12.5 0.33 10.9 6.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dynein_IC2 PF11540.6 001298552.2_18525001_2 - 4.6e-13 48.7 5.6 4.6e-13 48.7 5.6 2.4 2 0 0 2 2 2 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.30 001298552.2_18525001_2 - 1.3e-06 28.9 7.7 1.1 10.1 0.1 6.9 7 0 0 7 7 7 2 WD domain, G-beta repeat Hira PF07569.9 001298552.2_18525001_2 - 0.04 13.5 0.1 0.48 10.0 0.1 2.6 2 1 1 3 3 3 0 TUP1-like enhancer of split Frtz PF11768.6 001298552.2_18525001_2 - 0.051 11.7 0.1 2.3 6.3 0.1 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.4 001298552.2_18525001_2 - 0.058 13.8 1.2 29 5.2 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain ANAPC4_WD40 PF12894.5 001298552.2_18525001_2 - 0.071 13.3 0.0 33 4.7 0.0 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_5 PF08323.9 001298552.2_18525001_2 - 0.14 11.7 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain Lig_chan-Glu_bd PF10613.7 001169166.1_18529001_3 - 3e-29 101.4 0.0 9.2e-29 99.8 0.0 1.8 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.24 001169166.1_18529001_3 - 4.1e-29 101.2 0.9 8.4e-29 100.2 0.9 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.26 001169166.1_18529001_3 - 1.1e-27 96.9 1.3 7.1e-26 91.0 1.3 2.2 1 1 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.18 001169166.1_18529001_3 - 7.8e-25 87.5 0.0 2.6e-24 85.8 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2834 PF11196.6 001169166.1_18529001_3 - 3.3 8.0 8.7 8.5 6.7 8.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) Innexin PF00876.16 170660.2_18527001_2 - 3.9e-93 312.4 14.5 5e-93 312.0 14.5 1.1 1 0 0 1 1 1 1 Innexin Pkinase PF00069.23 001272293.1_18529001_3 - 1.5e-60 204.7 0.1 1.5e-60 204.7 0.1 2.7 3 0 0 3 3 3 1 Protein kinase domain SUIM_assoc PF16619.3 001272293.1_18529001_3 - 4.2 7.4 0.0 0.047 13.7 6.7 14.9 10 2 4 14 14 14 0 Unstructured region C-term to UIM in Ataxin3 Smoothelin PF12510.6 001272347.1_18529001_1 - 1.1e-39 134.1 26.3 2.4e-19 69.0 2.6 3.7 3 0 0 3 3 3 3 Smoothelin cytoskeleton protein CH PF00307.29 001272347.1_18529001_1 - 3.1e-23 81.9 0.1 6.9e-23 80.8 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.6 001272347.1_18529001_1 - 3.9e-06 26.5 0.0 8.1e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain Ank_2 PF12796.5 001201729.1_18529001_1 - 1.5e-38 131.1 2.9 4.2e-16 59.2 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001201729.1_18529001_1 - 8.8e-27 93.0 0.6 5.7e-14 52.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.4 001201729.1_18529001_1 - 2.6e-21 75.2 6.3 3.7e-09 36.6 0.1 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.28 001201729.1_18529001_1 - 6.5e-17 61.0 3.0 1.3e-05 25.3 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.4 001201729.1_18529001_1 - 3.1e-14 51.6 0.9 2.3e-05 24.3 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat DUF3915 PF13054.4 001201729.1_18529001_1 - 0.052 13.4 0.2 0.052 13.4 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3915) ELM2 PF01448.22 001201742.3_18528001_1 - 7e-14 52.2 0.2 1.6e-13 51.1 0.2 1.6 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.29 001201742.3_18528001_1 - 1.1e-10 41.3 0.5 0.00028 20.8 0.0 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001201742.3_18528001_1 - 0.00022 20.9 0.2 0.96 9.2 0.1 2.6 2 0 0 2 2 2 2 Myb DNA-binding like GATA PF00320.25 001201742.3_18528001_1 - 0.041 13.4 0.9 9 5.9 0.0 2.8 2 0 0 2 2 2 0 GATA zinc finger LIM PF00412.20 176758.3_18527001_2 - 3.3e-25 88.0 24.6 2e-12 47.0 10.7 2.5 2 0 0 2 2 2 2 LIM domain Spt20 PF12090.6 176758.3_18527001_2 - 0.093 12.2 13.6 0.72 9.3 0.3 2.3 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.3 176758.3_18527001_2 - 0.89 9.6 11.8 4.3 7.4 1.5 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Glyco_hydro_47 PF01532.18 206676.3_18528001_2 - 5.4e-151 503.4 0.1 6.6e-151 503.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4516 PF14990.4 001144699.2_18522001_2 - 1.2e-22 79.2 0.1 1.8e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) UPF0640 PF15114.4 001144699.2_18522001_3 - 3e-33 113.3 0.5 4.1e-33 112.9 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 RasGEF PF00617.17 001272362.1_18529001_1 - 1.2e-47 162.1 0.3 2.9e-47 160.9 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.18 001272362.1_18529001_1 - 1.2e-09 38.2 0.3 3.9e-09 36.6 0.3 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.20 001272296.1_18529001_1 - 1.9e-23 82.7 0.6 4.1e-23 81.6 0.6 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001272296.1_18529001_1 - 0.00023 21.3 0.0 0.00023 21.3 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF258 PF03193.14 001272296.1_18529001_1 - 0.0011 18.8 7.3 0.067 13.0 0.0 3.3 2 1 1 3 3 3 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001272296.1_18529001_1 - 0.0019 18.2 0.0 0.0048 16.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.4 001272296.1_18529001_1 - 0.045 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.19 001272296.1_18529001_1 - 0.047 13.0 0.5 0.29 10.4 0.5 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family SUIM_assoc PF16619.3 001272389.1_18529001_1 - 1.4 9.0 5.0 3.5 7.7 5.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-UBR PF02207.18 001272389.1_18529001_3 - 7.5e-18 64.3 10.2 7.5e-18 64.3 10.2 3.1 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.4 001272389.1_18529001_3 - 0.00046 20.3 0.6 0.00046 20.3 0.6 4.3 4 0 0 4 4 4 1 Ring finger domain Nexin_C PF08628.10 001272389.1_18529001_3 - 0.0026 18.3 2.4 0.0095 16.5 2.4 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal SUIM_assoc PF16619.3 001272388.1_18529001_1 - 1.3 9.0 5.1 3.5 7.7 5.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-UBR PF02207.18 001272388.1_18529001_3 - 7.5e-18 64.3 10.2 7.5e-18 64.3 10.2 3.1 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.4 001272388.1_18529001_3 - 0.00046 20.2 0.6 0.00046 20.2 0.6 4.3 4 0 0 4 4 4 1 Ring finger domain Nexin_C PF08628.10 001272388.1_18529001_3 - 0.0027 18.2 2.4 0.0095 16.5 2.4 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal Ion_trans_2 PF07885.14 001297940.1_18529001_1 - 1.9e-30 104.5 17.8 1.7e-16 59.8 0.6 2.8 3 0 0 3 3 3 2 Ion channel TFIIA PF03153.11 001297940.1_18529001_1 - 0.0011 19.0 16.0 0.0011 19.0 16.0 2.6 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Ion_trans PF00520.29 001297940.1_18529001_1 - 0.0015 17.6 12.2 0.044 12.9 0.0 2.7 3 0 0 3 3 3 2 Ion transport protein DUF2722 PF10846.6 001297940.1_18529001_1 - 0.002 17.0 22.2 0.054 12.3 13.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Lig_chan PF00060.24 001297940.1_18529001_1 - 0.0058 16.4 0.0 0.0058 16.4 0.0 2.3 2 0 0 2 2 2 1 Ligand-gated ion channel Band_3_cyto PF07565.11 001297940.1_18529001_1 - 0.2 11.3 6.2 1.3 8.6 2.2 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2254 PF10011.7 001297940.1_18529001_1 - 0.32 9.7 5.0 0.43 9.2 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF4407 PF14362.4 001297940.1_18529001_1 - 0.62 9.2 14.0 1.3 8.1 14.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pex14_N PF04695.11 001297940.1_18529001_1 - 5 7.7 28.8 0.4 11.2 8.9 4.5 4 1 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.7 001297940.1_18529001_1 - 6.9 6.9 11.4 4.5 7.5 3.5 2.8 3 0 0 3 3 3 0 Enhancer of polycomb-like TFIIA PF03153.11 001297940.1_18529001_3 - 0.12 12.2 4.5 0.2 11.5 4.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAP PF00188.24 001298050.1_18522001_3 - 1.4e-13 51.7 0.3 2.3e-13 51.0 0.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-RING_6 PF14835.4 001298050.1_18522001_3 - 0.012 15.3 0.2 0.033 13.9 0.2 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein SAPIS-gp6 PF16722.3 001298050.1_18522001_3 - 0.075 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus zf-C2HC PF01530.16 001272298.2_18529001_2 - 6.9e-28 96.4 24.5 4.8e-15 55.3 8.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2HC type IncA PF04156.12 001272298.2_18529001_2 - 0.67 9.6 0.0 0.67 9.6 0.0 5.4 4 2 0 4 4 4 0 IncA protein zf-C4 PF00105.16 001038734.2_18529001_1 - 4.6e-29 100.5 13.4 4.6e-29 100.5 13.4 2.7 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001038734.2_18529001_1 - 1.5e-10 40.9 1.8 5.1e-07 29.4 3.5 4.5 6 0 0 6 6 6 2 Ligand-binding domain of nuclear hormone receptor MIP-T3 PF10243.7 001038734.2_18529001_1 - 0.0004 19.1 22.1 0.0004 19.1 22.1 7.1 6 2 0 6 6 6 2 Microtubule-binding protein MIP-T3 DUF3915 PF13054.4 001038734.2_18529001_1 - 1.2 8.9 18.2 0.0067 16.3 4.5 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3915) zf-C4 PF00105.16 001272227.1_18529001_3 - 5.2e-29 100.4 13.4 5.2e-29 100.4 13.4 2.9 4 0 0 4 4 4 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001272227.1_18529001_3 - 9.5e-11 41.5 1.7 2.1e-07 30.6 3.1 5.3 7 0 0 7 7 7 2 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001272233.2_18529001_2 - 5.6e-29 100.3 13.4 5.6e-29 100.3 13.4 2.9 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001272233.2_18529001_2 - 1.2e-10 41.2 1.8 2.5e-07 30.4 3.2 5.3 7 0 0 7 7 7 2 Ligand-binding domain of nuclear hormone receptor RhoGEF PF00621.18 001272260.1_18529001_2 - 1.4e-12 48.1 0.4 2.4e-12 47.3 0.4 1.3 1 0 0 1 1 1 1 RhoGEF domain C2 PF00168.28 001272260.1_18529001_2 - 1.4e-11 44.5 0.0 3.4e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF4799 PF16056.3 001272260.1_18529001_2 - 6e-09 35.4 14.3 2.1e-08 33.6 0.2 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4799) PDZ PF00595.22 001272260.1_18529001_2 - 3.3e-06 27.2 0.0 7.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Rap_GAP PF02145.13 001298249.1_18529001_1 - 7.8e-62 208.0 0.0 1.8e-61 206.9 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP BTB PF00651.29 001298249.1_18529001_1 - 2.3e-10 40.6 0.0 1.1e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain LIM PF00412.20 001298249.1_18529001_1 - 7.6e-05 22.7 0.7 0.00025 21.1 0.7 1.9 1 0 0 1 1 1 1 LIM domain BACK PF07707.13 001298249.1_18529001_1 - 0.0019 18.1 0.2 0.0051 16.8 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch LIM PF00412.20 167625.3_18525001_1 - 1.1e-22 79.8 24.6 1.4e-12 47.5 10.7 3.2 3 0 0 3 3 3 2 LIM domain Spt20 PF12090.6 167625.3_18525001_1 - 0.027 13.9 21.7 0.48 9.9 0.2 3.2 3 0 0 3 3 3 0 Spt20 family SUIM_assoc PF16619.3 167625.3_18525001_1 - 0.045 13.7 23.3 1.8 8.6 1.7 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 AAA_34 PF13872.4 078589.4_18529001_3 - 3.8e-141 469.2 0.0 5.9e-141 468.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.4 078589.4_18529001_3 - 4e-123 410.1 0.0 7.2e-123 409.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.13 078589.4_18529001_3 - 2.4e-08 34.1 0.6 4.7e-07 29.8 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.29 078589.4_18529001_3 - 0.00077 19.7 0.2 0.0036 17.5 0.2 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CENP-B_dimeris PF09026.8 078589.4_18529001_3 - 2.7 8.3 27.9 0.7 10.2 5.6 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BUD22 PF09073.8 078589.4_18529001_3 - 7.6 5.6 36.5 4.6 6.3 29.0 2.5 2 0 0 2 2 2 0 BUD22 DPPIV_N PF00930.19 001272704.1_18529001_1 - 4.2e-56 190.1 0.9 2.4e-54 184.3 0.2 2.9 1 1 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.19 001272704.1_18529001_1 - 1.5e-36 125.8 0.2 2.4e-36 125.1 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.16 001272704.1_18529001_1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Dynein_IC2 PF11540.6 001316648.1_18525001_2 - 4e-13 48.9 5.6 4e-13 48.9 5.6 2.2 2 0 0 2 2 2 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.30 001316648.1_18525001_2 - 2.5e-06 28.0 10.4 0.95 10.3 0.1 7.3 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001316648.1_18525001_2 - 0.036 14.2 0.0 28 5.0 0.0 3.6 3 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.4 001316648.1_18525001_2 - 0.04 14.3 1.1 24 5.4 0.0 4.0 3 0 0 3 3 3 0 PQQ-like domain Frtz PF11768.6 001316648.1_18525001_2 - 0.04 12.1 0.1 2.1 6.4 0.1 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Glyco_transf_5 PF08323.9 001316648.1_18525001_2 - 0.11 12.0 0.0 0.94 9.0 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain CDRT4 PF15213.4 123753.1_18522120_3 - 0.092 13.2 1.9 0.14 12.7 1.9 1.2 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein CDRT4 PF15213.4 123755.1_18523120_3 - 0.18 12.2 1.7 0.27 11.7 1.7 1.2 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Tweety PF04906.11 133503.1_18521120_2 - 0.37 9.3 2.7 0.47 8.9 2.7 1.0 1 0 0 1 1 1 0 Tweety Calc_CGRP_IAPP PF00214.17 123768.1_18529120_3 - 0.14 12.4 1.2 0.32 11.2 0.3 2.0 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family Trypan_PARP PF05887.9 123768.1_18529120_3 - 0.85 9.5 7.3 1.6 8.6 7.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Imm_superinfect PF14373.4 123768.1_18529120_3 - 2 8.3 10.6 0.16 11.7 4.4 2.5 2 0 0 2 2 2 0 Superinfection immunity protein zf-UBP PF02148.17 133508.1_18521120_1 - 0.14 12.3 1.9 0.93 9.7 0.2 2.1 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DUF2956 PF11169.6 123791.1_18523120_2 - 0.037 14.1 0.4 0.074 13.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Atrophin-1 PF03154.13 123799.1_18522120_1 - 0.11 10.7 6.1 0.14 10.3 6.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 123799.1_18522120_1 - 1.3 8.9 6.8 1.9 8.4 6.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 123799.1_18522120_2 - 0.0073 14.5 13.5 0.0084 14.3 13.5 1.0 1 0 0 1 1 1 1 Atrophin-1 family DUF3915 PF13054.4 123799.1_18522120_2 - 0.2 11.5 7.5 0.29 11.0 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3915 PF13054.4 123799.1_18522120_3 - 0.017 15.0 2.5 0.025 14.4 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 123799.1_18522120_3 - 0.86 7.7 6.5 1.1 7.3 6.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family LRRNT PF01462.16 123814.1_18523120_1 - 2.9 7.5 7.9 4.9 6.8 0.0 3.0 2 1 1 3 3 3 0 Leucine rich repeat N-terminal domain LcrG PF07216.10 123815.1_18524120_1 - 0.34 10.7 4.3 8.5 6.3 0.3 2.4 2 0 0 2 2 2 0 LcrG protein SKG6 PF08693.8 123816.1_18526120_2 - 1.9 7.8 4.8 3.7 6.9 4.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PT PF04886.10 123821.1_18529120_3 - 1.6 8.2 27.3 3.4 7.1 6.0 2.4 2 0 0 2 2 2 0 PT repeat zf-Sec23_Sec24 PF04810.13 123822.1_18524120_1 - 0.052 13.5 1.2 0.12 12.3 1.2 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger SelP_N PF04592.12 123833.1_18522120_1 - 0.08 12.2 12.6 0.13 11.5 12.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.20 123833.1_18522120_1 - 7.7 5.5 7.5 11 5.0 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GRP PF07172.9 073642.2_18523120_2 - 5.1 7.7 7.2 9.4 6.9 7.2 1.3 1 0 0 1 1 1 0 Glycine rich protein family OstA PF03968.12 123841.2_18521120_2 - 0.053 13.6 0.6 0.065 13.3 0.6 1.1 1 0 0 1 1 1 0 OstA-like protein Elf1 PF05129.11 123843.1_18521120_1 - 0.0053 16.6 3.8 0.0053 16.6 3.8 2.0 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like TRP_N PF14558.4 073645.1_18521120_1 - 0.012 15.8 0.1 0.014 15.7 0.1 1.1 1 0 0 1 1 1 0 ML-like domain TMEM52 PF14979.4 123892.1_18527120_1 - 0.028 14.2 0.2 0.066 13.0 0.2 1.5 1 0 0 1 1 1 0 Transmembrane 52 Nop14 PF04147.10 123892.1_18527120_2 - 0.15 10.1 12.1 0.25 9.4 12.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.12 123892.1_18527120_2 - 0.53 8.4 11.7 0.89 7.6 11.7 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.10 123892.1_18527120_2 - 2.7 7.2 9.1 4.5 6.4 9.1 1.3 1 0 0 1 1 1 0 NOA36 protein TMEM52 PF14979.4 123893.1_18524120_2 - 0.017 14.9 0.2 0.028 14.2 0.2 1.3 1 0 0 1 1 1 0 Transmembrane 52 Nop14 PF04147.10 123893.1_18524120_3 - 0.067 11.3 12.2 0.097 10.7 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.12 123893.1_18524120_3 - 0.25 9.5 11.7 0.39 8.8 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein M_domain PF12938.5 123893.1_18524120_3 - 1.1 8.9 9.1 0.83 9.3 3.0 2.3 2 0 0 2 2 2 0 M domain of GW182 NOA36 PF06524.10 123893.1_18524120_3 - 1.2 8.3 9.1 2.2 7.5 9.1 1.4 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.12 123893.1_18524120_3 - 3.2 7.4 11.3 6.8 6.3 11.3 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.10 123893.1_18524120_3 - 4.3 6.8 21.8 9.6 5.7 21.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFB6 PF17110.3 123893.1_18524120_3 - 5.4 6.6 7.7 12 5.4 7.7 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CENP-B_dimeris PF09026.8 123893.1_18524120_3 - 8.7 6.7 17.5 18 5.6 17.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ter PF05472.9 123895.1_18522120_1 - 0.011 14.6 0.2 0.014 14.4 0.2 1.1 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) CPSF73-100_C PF11718.6 123895.1_18522120_1 - 0.85 9.1 5.6 0.35 10.4 2.5 1.7 1 1 1 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Galanin PF01296.16 133524.1_18524120_2 - 0.025 14.4 7.9 24 4.9 0.0 5.4 5 0 0 5 5 5 0 Galanin TGF_beta_GS PF08515.10 133524.1_18524120_2 - 0.41 10.1 10.2 45 3.5 0.0 6.3 7 0 0 7 7 7 0 Transforming growth factor beta type I GS-motif Colicin_Ia PF11504.6 133524.1_18524120_2 - 1.1 9.2 3.3 49 4.0 0.0 3.3 2 1 1 3 3 3 0 Colicin Ia KRTAP PF11759.6 123911.1_18522120_3 - 0.021 15.3 2.7 0.04 14.3 2.7 1.4 1 0 0 1 1 1 0 Keratin-associated matrix Epiglycanin_C PF14654.4 123911.1_18522120_3 - 0.093 12.7 1.7 0.15 12.0 1.7 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Spike_NTD PF16451.3 133526.1_18522120_2 - 0.025 13.8 0.2 0.036 13.3 0.2 1.1 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain Spike_NTD PF16451.3 123923.1_18522120_2 - 0.021 14.1 0.2 0.029 13.6 0.2 1.1 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain MraZ PF02381.16 123929.1_18521120_2 - 0.04 13.8 0.1 0.057 13.3 0.1 1.2 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like FdtA PF05523.9 073659.2_18522120_3 - 0.14 11.7 0.2 0.21 11.2 0.2 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal DUF3544 PF12064.6 123946.1_18521120_2 - 0.048 13.8 0.0 0.061 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) MecA PF05389.10 123957.1_18522120_2 - 0.0077 15.8 0.7 0.0084 15.6 0.7 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) SPICE PF15678.3 123957.1_18522120_2 - 1 8.5 12.0 1.3 8.2 12.0 1.1 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression DUF4363 PF14276.4 123968.1_18522120_3 - 0.043 13.7 0.3 0.079 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DUF1674 PF07896.10 123972.1_18523120_1 - 0.17 12.3 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) YajC PF02699.13 123983.1_18521120_1 - 0.2 11.5 1.7 0.29 10.9 1.7 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Mucin PF01456.15 123983.1_18521120_3 - 8.2 6.3 18.2 10 6.0 18.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein PEGSRP PF07623.9 123987.1_18522120_2 - 0.16 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) DUF1569 PF07606.9 123992.1_18522120_2 - 0.05 13.5 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) Metallophos PF00149.26 001015497.4_18523001_3 - 1.8e-36 126.5 0.1 2.3e-36 126.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.3 001015497.4_18523001_3 - 9.9e-15 54.6 3.2 2.1e-14 53.5 3.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain HABP4_PAI-RBP1 PF04774.13 001316650.1_18523001_2 - 2.2e-25 89.6 8.7 2.2e-25 89.6 8.7 2.3 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family LRRNT_2 PF08263.10 001316650.1_18523001_3 - 0.48 10.6 5.0 0.54 10.5 0.1 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain CK_II_beta PF01214.16 048532.2_18524120_3 - 5.6e-24 84.9 0.0 9.3e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026622.2_18522120_1 - 3.1e-10 40.1 0.0 5.8e-09 35.9 0.0 2.0 2 0 0 2 2 2 2 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026622.2_18522120_2 - 0.0078 15.9 0.9 0.015 15.0 0.9 1.4 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026622.2_18522120_3 - 3.1e-07 30.3 0.3 3.1e-07 30.3 0.3 1.5 2 0 0 2 2 2 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 048531.2_18523120_1 - 0.0031 17.2 0.1 0.0053 16.5 0.1 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 048531.2_18523120_3 - 7.3e-19 68.2 1.7 9.9e-12 44.9 0.1 2.4 2 0 0 2 2 2 2 Casein kinase II regulatory subunit CK_II_beta PF01214.16 125437.1_18522120_1 - 1.4e-25 90.1 0.6 1.9e-25 89.6 0.6 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026606.2_18523120_3 - 1.4e-17 63.9 1.5 2.5e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Casein kinase II regulatory subunit CK_II_beta PF01214.16 133546.1_18523120_1 - 5.9e-15 55.4 1.4 8.8e-15 54.9 1.4 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 133546.1_18523120_2 - 0.0015 18.2 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026604.2_18523120_1 - 6.2e-08 32.6 0.0 9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026604.2_18523120_3 - 4.6e-27 94.9 0.0 7.5e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026608.1_18524120_1 - 1.2e-25 90.3 0.0 1.9e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026608.1_18524120_2 - 4e-07 29.9 0.6 6.1e-07 29.3 0.6 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026619.2_18524120_1 - 3e-18 66.2 0.7 4.5e-18 65.6 0.7 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026619.2_18524120_3 - 0.00014 21.6 0.2 0.0016 18.2 0.2 2.1 2 0 0 2 2 2 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026611.1_18522120_1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 133548.1_18523120_1 - 6.1e-08 32.6 0.6 2.7e-07 30.5 0.6 1.8 2 0 0 2 2 2 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 133548.1_18523120_2 - 4.5e-12 46.1 1.1 6.6e-12 45.5 1.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 133548.1_18523120_3 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Ectatomin PF06457.9 048530.1_18522120_1 - 0.036 13.8 1.0 0.089 12.6 1.0 1.6 1 0 0 1 1 1 0 Ectatomin CK_II_beta PF01214.16 048530.1_18522120_3 - 5e-19 68.7 0.0 6.9e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026623.2_18524120_2 - 2.9e-26 92.3 0.1 5e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026623.2_18524120_3 - 2.9e-07 30.4 0.6 4.3e-07 29.8 0.6 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Gelsolin PF00626.20 206426.4_18526001_2 - 6.5e-71 234.1 3.1 3.4e-14 52.4 0.0 6.1 6 1 0 6 6 6 5 Gelsolin repeat F-box-like PF12937.5 164340.4_18525001_3 - 2.8e-11 43.0 2.3 3.1e-11 42.8 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.31 164340.4_18525001_3 - 7.7e-10 38.3 1.9 2.5e-09 36.7 1.9 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.5 164340.4_18525001_3 - 1.1e-05 25.5 7.6 0.62 10.4 0.5 4.9 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.4 164340.4_18525001_3 - 0.00023 20.9 4.0 3.5 7.8 0.1 5.8 6 0 0 6 6 6 2 Leucine Rich repeat Claudin_2 PF13903.4 141199.4_18523001_1 - 0.013 15.2 14.1 0.71 9.5 14.1 2.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.9 141199.4_18523001_1 - 0.87 9.4 12.9 4.8 7.0 12.8 2.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like ELO PF01151.16 169003.4_18525001_2 - 3.9e-66 223.0 28.2 3.9e-66 223.0 28.2 1.6 2 0 0 2 2 2 1 GNS1/SUR4 family ELO PF01151.16 169001.4_18525001_1 - 5.6e-66 222.5 28.1 5.6e-66 222.5 28.1 1.7 2 0 0 2 2 2 1 GNS1/SUR4 family ELO PF01151.16 001259976.2_18525001_1 - 3.2e-66 223.3 28.2 3.2e-66 223.3 28.2 1.7 2 0 0 2 2 2 1 GNS1/SUR4 family LIM PF00412.20 141231.4_18528001_2 - 1.1e-06 28.6 7.6 4.7e-06 26.6 7.6 2.0 1 1 0 1 1 1 1 LIM domain HECT PF00632.23 141239.5_18529001_1 - 3.4e-80 269.7 0.1 6.9e-80 268.7 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WWE PF02825.18 141239.5_18529001_1 - 3.3e-20 72.3 1.4 9.8e-20 70.7 1.4 1.9 1 0 0 1 1 1 1 WWE domain HEAT_2 PF13646.4 141239.5_18529001_1 - 0.0046 17.2 1.0 0.12 12.7 0.1 3.6 4 0 0 4 4 4 1 HEAT repeats Arm PF00514.21 141239.5_18529001_1 - 0.023 14.6 6.4 0.12 12.3 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat NTP_transferase PF00483.21 001202248.2_18524001_3 - 3.8e-53 180.5 0.0 6e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001202248.2_18524001_3 - 8.8e-11 42.3 0.0 1.2e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001202248.2_18524001_3 - 1.7e-10 40.0 7.5 9.1e-09 34.6 1.9 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.4 001202248.2_18524001_3 - 0.00027 20.5 6.1 0.0029 17.2 2.7 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.17 001202248.2_18524001_3 - 0.056 13.0 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF1412 PF07203.9 001202248.2_18524001_3 - 0.14 12.2 0.0 0.66 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) JHBP PF06585.9 141250.3_18523001_1 - 1.5e-72 243.5 0.8 1.8e-72 243.3 0.8 1.0 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) RA PF00788.21 079508.4_18529001_1 - 3.1e-41 139.8 0.6 1.4e-21 76.8 0.0 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain DIL PF01843.17 079508.4_18529001_1 - 8.1e-25 87.0 7.3 8.1e-25 87.0 7.3 2.6 2 1 0 2 2 2 1 DIL domain PDZ PF00595.22 079508.4_18529001_1 - 1.4e-16 60.4 0.3 4.7e-16 58.8 0.3 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FHA PF00498.24 079508.4_18529001_1 - 2.7e-08 33.9 0.0 6.9e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain PDZ_2 PF13180.4 079508.4_18529001_1 - 0.00068 19.8 0.1 0.0023 18.1 0.1 1.9 1 0 0 1 1 1 1 PDZ domain Yop-YscD_cpl PF16697.3 079508.4_18529001_1 - 0.0026 17.9 0.0 0.01 16.0 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FERM_f0 PF16511.3 079508.4_18529001_1 - 0.045 13.9 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM E1_UFD PF09358.8 079508.4_18529001_1 - 0.11 13.1 0.3 4.6 7.9 0.0 3.2 2 0 0 2 2 2 0 Ubiquitin fold domain TLD PF07534.14 170644.3_18529001_1 - 2.6e-34 118.3 0.2 4e-34 117.7 0.2 1.3 1 0 0 1 1 1 1 TLD SLC12 PF03522.13 169057.1_18528001_2 - 1.9e-135 451.9 0.0 2.4e-135 451.6 0.0 1.1 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.19 169057.1_18528001_2 - 3.9e-104 348.8 36.6 4.8e-104 348.5 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease Pex24p PF06398.9 169057.1_18528001_2 - 0.14 10.9 0.9 0.4 9.5 0.9 1.7 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Sec23_trunk PF04811.13 169089.4_18526001_3 - 2.8e-83 279.1 0.0 4.1e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.10 169089.4_18526001_3 - 2.1e-33 114.8 0.1 4.3e-33 113.8 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.13 169089.4_18526001_3 - 4.2e-28 97.0 0.1 1.1e-27 95.7 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.13 169089.4_18526001_3 - 1.9e-15 56.5 8.0 3.7e-15 55.5 8.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.20 169089.4_18526001_3 - 8e-14 51.2 0.0 1.8e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat RAMP4 PF06624.10 169093.3_18527001_1 - 0.27 11.2 2.0 2 8.4 2.0 2.6 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 AAA PF00004.27 141329.3_18525001_1 - 9.3e-40 136.0 0.0 1.6e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.8 141329.3_18525001_1 - 1.4e-07 31.3 0.1 3.8e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.10 141329.3_18525001_1 - 7.8e-06 25.2 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.4 141329.3_18525001_1 - 1.7e-05 24.9 0.0 4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.12 141329.3_18525001_1 - 0.00019 21.3 0.4 0.0026 17.6 0.4 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.11 141329.3_18525001_1 - 0.00026 19.9 0.0 0.00054 18.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.19 141329.3_18525001_1 - 0.0011 18.2 0.2 0.0029 16.9 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.12 141329.3_18525001_1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TsaE PF02367.15 141329.3_18525001_1 - 0.0037 17.1 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.4 141329.3_18525001_1 - 0.004 17.5 0.0 0.0099 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.15 141329.3_18525001_1 - 0.0046 16.6 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.4 141329.3_18525001_1 - 0.0048 17.0 0.6 0.094 12.9 0.6 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.4 141329.3_18525001_1 - 0.0052 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.4 141329.3_18525001_1 - 0.015 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.10 141329.3_18525001_1 - 0.027 14.3 0.4 0.12 12.2 0.1 2.2 2 1 0 2 2 2 0 NACHT domain ATPase PF06745.11 141329.3_18525001_1 - 0.073 12.3 0.1 2.5 7.2 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.4 141329.3_18525001_1 - 0.095 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.14 141329.3_18525001_1 - 0.098 12.0 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.4 141329.3_18525001_1 - 0.26 11.6 1.1 0.46 10.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain Globin PF00042.20 141340.3_18523001_3 - 0.00052 20.4 0.1 0.00086 19.7 0.1 1.4 1 0 0 1 1 1 1 Globin T2SSG PF08334.9 141340.3_18523001_3 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Sugar_tr PF00083.22 141341.3_18525001_1 - 2.3e-87 293.6 27.7 3e-87 293.2 27.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 141341.3_18525001_1 - 4e-25 88.4 44.3 3.3e-19 68.9 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RFX_DNA_binding PF02257.13 141399.3_18529001_3 - 1e-28 99.6 0.1 1.9e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.14 141399.3_18529001_3 - 0.013 15.8 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Poxvirus D5 protein-like Acetyltransf_7 PF13508.5 141439.3_18522001_3 - 0.058 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.8 141439.3_18522001_3 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.5 169174.3_18523001_2 - 0.0089 16.3 0.0 0.024 14.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.23 169174.3_18523001_2 - 0.0099 16.0 0.2 0.02 15.0 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.8 169174.3_18523001_2 - 0.013 15.3 0.0 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein CBM_14 PF01607.22 001104229.3_18529001_1 - 8.9e-14 51.3 4.9 1.6e-13 50.4 4.9 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain MDM1 PF15501.4 141487.3_18525001_1 - 1.4e-67 229.1 13.2 1.4e-67 229.0 11.4 1.8 1 1 0 1 1 1 1 Nuclear protein MDM1 LRR_8 PF13855.4 141513.3_18524001_3 - 3.5e-40 135.4 29.6 3.6e-15 55.3 1.8 7.5 5 1 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.5 141513.3_18524001_3 - 6.3e-18 64.4 36.1 0.00056 20.1 1.5 9.2 5 3 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 141513.3_18524001_3 - 2e-08 33.8 5.8 0.0046 16.3 0.3 4.1 2 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.31 141513.3_18524001_3 - 9.1e-08 31.4 32.2 5.8 7.7 0.4 11.6 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_5 PF13306.4 141513.3_18524001_3 - 0.00016 21.5 0.0 0.0017 18.2 0.0 2.6 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_6 PF13516.4 141513.3_18524001_3 - 2 8.5 19.2 8.3 6.6 0.1 8.9 10 0 0 10 10 10 0 Leucine Rich repeat 7tm_6 PF02949.18 079555.2_18523001_1 - 9.9e-72 241.5 13.2 1.3e-71 241.1 13.2 1.2 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 079555.2_18523001_1 - 6.8e-11 41.8 19.8 1.1e-10 41.2 19.8 1.4 1 1 0 1 1 1 1 7tm Chemosensory receptor Transketolase_N PF00456.19 169231.2_18525001_1 - 2.8e-48 164.5 0.0 4.9e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.22 169231.2_18525001_1 - 5.1e-41 140.2 0.0 1.1e-40 139.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 169231.2_18525001_1 - 2.5e-32 111.2 0.1 6.4e-32 109.9 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.18 169231.2_18525001_1 - 3.9e-11 42.3 0.0 6.2e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.4 169231.2_18525001_1 - 1.8e-05 24.0 0.2 0.0012 18.0 0.1 2.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.19 169231.2_18525001_1 - 0.00016 21.4 0.6 0.0022 17.7 0.3 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.8 169231.2_18525001_1 - 0.005 15.5 0.1 0.009 14.7 0.1 1.3 1 0 0 1 1 1 1 XFP N-terminal domain Bd3614-deam PF14439.4 141566.2_18523001_1 - 1.2 9.0 3.4 2.1 8.3 3.4 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase zf-H2C2_2 PF13465.4 141566.2_18523001_3 - 5.5e-20 70.7 33.9 2.5e-06 27.6 0.3 6.0 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 141566.2_18523001_3 - 3.3e-14 52.2 40.4 0.0016 19.0 0.3 6.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.24 141566.2_18523001_3 - 1e-11 44.5 42.2 0.00058 20.0 0.3 6.3 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-AD PF07776.13 141566.2_18523001_3 - 1e-11 44.8 4.6 1e-11 44.8 4.6 3.6 3 1 0 4 4 4 1 Zinc-finger associated domain (zf-AD) zf-met PF12874.5 141566.2_18523001_3 - 4.4e-09 36.3 3.7 4.4e-09 36.3 3.7 6.1 7 0 0 7 7 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 141566.2_18523001_3 - 5.9e-08 32.7 23.7 0.0023 18.0 3.7 6.5 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 141566.2_18523001_3 - 0.029 14.0 26.3 0.15 11.7 0.8 5.7 5 0 0 5 5 5 0 zinc-finger C2H2-type XPA_N PF01286.16 141566.2_18523001_3 - 0.098 12.6 0.1 0.098 12.6 0.1 6.3 8 0 0 8 8 8 0 XPA protein N-terminal Arc_trans_TRASH PF08394.8 141566.2_18523001_3 - 0.12 12.6 5.1 3.8 7.8 0.0 3.5 3 1 0 3 3 3 0 Archaeal TRASH domain zf-AN1 PF01428.14 141566.2_18523001_3 - 0.15 12.1 18.1 16 5.7 0.1 6.0 6 0 0 6 6 6 0 AN1-like Zinc finger PyrI_C PF02748.13 141566.2_18523001_3 - 0.17 11.7 5.3 0.8 9.5 0.4 3.5 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.4 141566.2_18523001_3 - 0.27 11.1 15.3 3 7.7 1.3 4.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-BED PF02892.13 141566.2_18523001_3 - 0.93 9.5 26.7 4.4 7.3 0.7 5.1 3 1 2 5 5 5 0 BED zinc finger C1_1 PF00130.20 141566.2_18523001_3 - 0.94 9.3 22.5 0.082 12.7 1.3 4.5 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rep_fac-A_C PF08646.8 141566.2_18523001_3 - 2.6 7.7 9.2 16 5.1 0.2 4.2 3 1 2 5 5 4 0 Replication factor-A C terminal domain FYDLN_acid PF09538.8 141566.2_18523001_3 - 3.8 8.1 6.9 9 6.9 0.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DZR PF12773.5 141566.2_18523001_3 - 9.9 6.1 21.8 17 5.4 2.5 4.6 2 2 1 4 4 4 0 Double zinc ribbon RHD_DNA_bind PF00554.20 057746.4_18527001_3 - 1.1e-52 178.3 0.9 2.3e-52 177.2 0.4 1.9 2 0 0 2 2 2 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 057746.4_18527001_3 - 5.8e-35 119.3 0.0 1.2e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.5 057746.4_18527001_3 - 1.2e-19 70.6 8.9 2.3e-14 53.6 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.28 057746.4_18527001_3 - 5.6e-18 64.4 2.4 0.0031 17.8 0.2 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.4 057746.4_18527001_3 - 5.8e-15 55.3 3.4 2.9e-06 27.6 0.1 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.4 057746.4_18527001_3 - 1.6e-14 53.6 6.5 0.00011 22.4 0.6 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 057746.4_18527001_3 - 2.1e-14 52.1 0.5 0.0066 16.7 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ribonuc_P_40 PF08584.9 057746.4_18527001_3 - 0.059 12.5 0.3 0.14 11.3 0.3 1.5 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DUF4150 PF13665.4 141622.4_18523001_3 - 0.01 15.8 1.1 0.021 14.8 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) zf-A20 PF01754.14 001031990.4_18525001_3 - 1.1e-12 47.5 5.4 3.1e-12 46.1 5.4 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.14 001031990.4_18525001_3 - 1.1e-09 38.1 7.8 3.1e-09 36.7 7.8 1.8 1 0 0 1 1 1 1 AN1-like Zinc finger MBD PF01429.17 169293.2_18523001_1 - 5.8e-36 121.9 0.0 9.4e-24 82.8 0.0 2.2 2 0 0 2 2 2 2 Methyl-CpG binding domain MBD_C PF14048.4 169293.2_18523001_1 - 2.9e-29 101.5 0.2 2.9e-29 101.5 0.2 2.6 3 0 0 3 3 3 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.3 169293.2_18523001_1 - 1.4e-27 95.6 4.7 2.7e-27 94.6 4.7 1.5 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD DUF3446 PF11928.6 169293.2_18523001_1 - 1.2 9.3 9.4 2.8 8.2 3.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) M_domain PF12938.5 169293.2_18523001_1 - 1.6 8.4 14.8 0.021 14.5 5.9 2.1 2 0 0 2 2 2 0 M domain of GW182 AAA PF00004.27 141653.5_18526001_3 - 5.3e-12 46.2 0.1 4.1e-11 43.3 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.25 141653.5_18526001_3 - 0.00028 20.3 1.8 0.00082 18.8 1.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_23 PF13476.4 141653.5_18526001_3 - 1.5 9.2 14.0 1.5 9.1 1.1 3.6 3 0 0 3 3 3 0 AAA domain zf-C2H2_4 PF13894.4 169309.5_18525001_3 - 7.8e-07 29.3 14.2 0.033 14.9 1.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.24 169309.5_18525001_3 - 2.3e-06 27.6 15.8 0.00071 19.8 1.9 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type C1_4 PF07975.10 169309.5_18525001_3 - 0.0069 16.5 1.7 5.9 7.1 0.0 3.7 3 0 0 3 3 3 1 TFIIH C1-like domain THF_DHG_CYH_C PF02882.17 169309.5_18525001_3 - 0.0079 15.4 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-FCS PF06467.12 169309.5_18525001_3 - 0.25 11.2 6.7 4 7.4 0.2 3.7 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.4 169309.5_18525001_3 - 0.26 11.7 8.3 4.7 7.7 0.1 4.0 3 1 0 3 3 3 0 Zinc-finger double domain OTT_1508_deam PF14441.4 169309.5_18525001_3 - 0.31 10.8 3.4 1.1 9.2 0.1 3.0 2 1 1 3 3 3 0 OTT_1508-like deaminase zf-C2H2_2 PF12756.5 169309.5_18525001_3 - 1.8 8.8 8.9 18 5.6 0.6 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.6 169309.5_18525001_3 - 4 7.7 9.8 3.3 8.0 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3585 PF12130.6 001260087.3_18529001_2 - 5.1e-23 81.6 15.0 5.1e-23 81.6 15.0 4.4 3 0 0 3 3 1 1 Protein of unknown function (DUF3585) CH PF00307.29 001260087.3_18529001_2 - 3.5e-09 36.7 0.0 1.1e-08 35.1 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain Pyr_redox_2 PF07992.12 001260087.3_18529001_2 - 7.5e-06 25.3 0.2 0.0002 20.5 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase LIM PF00412.20 001260087.3_18529001_2 - 1.4e-05 25.0 6.0 3.6e-05 23.8 6.0 1.7 1 0 0 1 1 1 1 LIM domain Pyr_redox_3 PF13738.4 001260087.3_18529001_2 - 5.9e-05 22.3 0.0 5.9e-05 22.3 0.0 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001260087.3_18529001_2 - 0.00023 19.9 0.0 0.00071 18.2 0.0 1.9 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.22 001260087.3_18529001_2 - 0.00066 18.7 0.1 0.00066 18.7 0.1 1.9 2 0 0 2 2 1 1 FAD binding domain AlaDh_PNT_C PF01262.19 001260087.3_18529001_2 - 0.00088 18.5 0.6 0.0058 15.8 0.2 2.4 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.17 001260087.3_18529001_2 - 0.00093 18.4 0.2 0.0024 17.1 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.22 001260087.3_18529001_2 - 0.0092 15.5 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.25 001260087.3_18529001_2 - 0.011 16.2 0.1 0.034 14.6 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001260087.3_18529001_2 - 0.017 15.2 0.0 0.017 15.2 0.0 2.3 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain CAMSAP_CH PF11971.6 001260087.3_18529001_2 - 0.018 14.8 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain Lycopene_cycl PF05834.10 001260087.3_18529001_2 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MutS_II PF05188.15 001260087.3_18529001_2 - 0.79 9.9 3.6 3.6 7.7 3.6 2.2 1 0 0 1 1 1 0 MutS domain II zf-FCS PF06467.12 001260087.3_18529001_2 - 2.3 8.1 5.9 2.5 8.0 1.7 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RrnaAD PF00398.18 141714.4_18524001_3 - 4.9e-11 42.1 0.0 6.5e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Synapsin_C PF02750.12 176451.3_18529001_1 - 2.2e-73 246.0 0.0 3.3e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.14 176451.3_18529001_1 - 1.4e-43 147.1 0.0 7.7e-42 141.6 0.0 2.3 2 0 0 2 2 2 1 Synapsin, N-terminal domain Pkinase PF00069.23 141736.3_18529001_2 - 1.3e-75 254.1 1.3 2.4e-75 253.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 141736.3_18529001_2 - 6.4e-44 150.1 0.0 1.2e-43 149.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 141736.3_18529001_2 - 3e-06 26.6 0.8 6.4e-06 25.5 0.8 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 141736.3_18529001_2 - 0.0032 17.0 0.4 0.0075 15.8 0.4 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.4 141736.3_18529001_2 - 0.029 13.5 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.21 141736.3_18529001_2 - 0.052 13.3 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTHFS PF01268.17 169350.3_18527001_1 - 3.1e-248 824.4 0.5 3.8e-248 824.1 0.5 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.17 169350.3_18527001_1 - 3.1e-64 215.0 0.5 3.1e-64 215.0 0.5 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.21 169350.3_18527001_1 - 4.6e-36 123.5 0.3 9.6e-36 122.5 0.3 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AcetDehyd-dimer PF09290.9 169350.3_18527001_1 - 0.0022 18.1 0.0 0.0071 16.4 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic acetaldehyde dehydrogenase, dimerisation Peptidase_C39 PF03412.13 169350.3_18527001_1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase C39 family MFS_1 PF07690.14 141756.5_18525001_3 - 5.5e-22 78.0 36.5 6.3e-17 61.4 7.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 141756.5_18525001_3 - 2.1e-16 59.7 4.3 2.1e-16 59.7 4.3 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Ribosomal_L3 PF00297.20 079592.3_18523001_1 - 9.9e-178 590.6 11.9 1.1e-177 590.4 11.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 CAP PF00188.24 141796.2_18522001_2 - 1e-11 45.7 0.1 1.6e-11 45.0 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-RanBP PF00641.16 141850.2_18525001_1 - 3.6e-09 35.6 19.6 6.9e-05 21.9 7.1 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.20 141850.2_18525001_1 - 3.1e-07 30.0 0.1 1e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cortexin PF11057.6 141850.2_18525001_3 - 0.11 12.2 0.5 0.22 11.3 0.5 1.4 1 0 0 1 1 1 0 Cortexin of kidney FYRN PF05964.12 169443.3_18523001_1 - 0.052 13.3 0.1 0.052 13.3 0.1 2.1 2 0 0 2 2 2 0 F/Y-rich N-terminus Mito_carr PF00153.25 169443.3_18523001_2 - 3.3e-62 206.3 3.6 2.1e-23 81.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SDF PF00375.16 169443.3_18523001_2 - 0.0082 15.1 0.0 0.03 13.2 0.0 1.7 2 0 0 2 2 2 1 Sodium:dicarboxylate symporter family UDPGT PF00201.16 141972.2_18524001_2 - 1.6e-63 215.1 0.0 2.1e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 141972.2_18524001_2 - 1.4e-06 28.2 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.4 141972.2_18524001_2 - 0.0011 18.2 0.0 0.0029 16.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 1 EF-hand_1 PF00036.30 176487.2_18522001_3 - 2.1e-19 67.4 8.5 5.1e-05 22.4 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 176487.2_18522001_3 - 1.1e-18 67.3 5.0 4.3e-09 36.6 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 176487.2_18522001_3 - 5.8e-18 63.1 3.7 8.6e-05 22.1 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 176487.2_18522001_3 - 5.1e-14 50.9 6.9 8.7e-05 21.7 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 176487.2_18522001_3 - 3.8e-11 42.5 11.6 3e-05 23.6 1.4 4.4 3 2 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.7 176487.2_18522001_3 - 0.018 15.2 0.0 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1676 PF07898.11 001038961.2_18523001_3 - 0.01 15.8 7.9 0.31 10.9 7.9 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1676) SMK-1 PF04802.13 142047.4_18529001_3 - 1.1e-75 253.6 5.4 2.5e-75 252.4 5.4 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.16 142047.4_18529001_3 - 0.0033 17.5 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain BTB PF00651.29 169564.2_18528001_1 - 1.8e-32 111.7 0.3 4e-32 110.6 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.24 169564.2_18528001_1 - 3.7e-06 26.9 0.6 2.9e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 MATH domain DIM PF08194.10 143955.2_18521001_3 - 0.00019 21.4 0.9 0.0003 20.8 0.9 1.3 1 0 0 1 1 1 1 DIM protein zf-H2C2_2 PF13465.4 142172.3_18525001_2 - 8.1e-42 139.7 62.8 9.7e-09 35.2 2.4 10.6 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2 PF00096.24 142172.3_18525001_2 - 6.6e-37 123.8 67.4 7.2e-06 26.1 0.7 10.5 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 142172.3_18525001_2 - 5.9e-32 107.4 63.7 0.0015 19.1 0.6 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.4 142172.3_18525001_2 - 3.8e-22 77.6 53.0 0.0021 17.8 0.0 10.7 10 1 0 10 10 10 7 C2H2-type zinc finger zf-AD PF07776.13 142172.3_18525001_2 - 8.2e-15 54.7 2.6 8.2e-15 54.7 2.6 4.0 2 1 3 5 5 5 1 Zinc-finger associated domain (zf-AD) zf-met PF12874.5 142172.3_18525001_2 - 2.7e-14 52.9 56.5 0.026 14.8 0.4 10.4 10 0 0 10 10 10 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 142172.3_18525001_2 - 3.5e-06 27.0 44.0 0.12 12.6 0.1 9.9 10 0 0 10 10 10 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.10 142172.3_18525001_2 - 1.8e-05 24.8 4.7 1.8e-05 24.8 4.7 6.0 2 1 5 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.3 142172.3_18525001_2 - 0.00075 19.6 6.7 0.00075 19.6 6.7 5.2 1 1 3 5 5 5 2 C2H2-type zinc ribbon zf-C2H2_9 PF16293.3 142172.3_18525001_2 - 0.003 17.2 1.6 0.055 13.2 0.2 6.8 8 1 1 9 9 9 2 C2H2 type zinc-finger (1 copy) DUF3268 PF11672.6 142172.3_18525001_2 - 0.02 15.1 0.5 0.02 15.1 0.5 4.9 3 2 2 5 5 5 0 zinc-finger-containing domain GAGA PF09237.9 142172.3_18525001_2 - 0.024 14.3 15.2 0.26 11.0 0.2 5.4 2 2 3 5 5 5 0 GAGA factor zf-H2C2_5 PF13909.4 142172.3_18525001_2 - 0.043 13.5 0.3 0.043 13.5 0.3 8.1 8 0 0 8 8 8 0 C2H2-type zinc-finger domain UBZ_FAAP20 PF15750.3 142172.3_18525001_2 - 2.1 8.2 14.2 13 5.7 0.2 5.5 5 0 0 5 5 4 0 Ubiquitin-binding zinc-finger FOXP-CC PF16159.3 142172.3_18525001_2 - 3.4 8.2 11.6 1.4 9.5 2.2 3.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.5 142172.3_18525001_2 - 9.5 6.5 54.2 1 9.6 0.9 8.5 2 1 8 10 10 9 0 C2H2 type zinc-finger (2 copies) Fibrinogen_C PF00147.16 142236.2_18523001_2 - 8.5e-45 153.1 1.5 1e-44 152.8 1.5 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain GATA PF00320.25 142259.4_18527001_1 - 9.9e-13 47.3 7.8 9.9e-13 47.3 7.8 2.0 2 0 0 2 2 2 1 GATA zinc finger Auto_anti-p27 PF06677.10 142259.4_18527001_1 - 0.057 13.5 8.6 0.11 12.5 1.5 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.10 142259.4_18527001_1 - 0.74 9.2 11.4 0.4 10.1 1.9 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.5 142259.4_18527001_1 - 1.5 8.8 11.5 20 5.2 11.8 2.6 1 1 1 2 2 2 0 Double zinc ribbon DUF3716 PF12511.6 142259.4_18527001_1 - 2.4 8.1 6.3 1.9 8.5 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) A2L_zn_ribbon PF08792.8 142259.4_18527001_1 - 3.8 7.2 8.9 0.54 9.9 1.0 2.7 2 0 0 2 2 2 0 A2L zinc ribbon domain MAT1 PF06391.11 142259.4_18527001_1 - 4.7 6.8 36.0 0.13 11.9 17.9 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 OrfB_Zn_ribbon PF07282.9 142259.4_18527001_1 - 9.3 6.1 7.5 5.1 7.0 0.9 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain NAD_binding_4 PF07993.10 142309.2_18524001_2 - 6.6e-77 258.0 0.0 8.2e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.17 142309.2_18524001_2 - 1.3e-31 108.5 1.8 1.8e-31 108.0 0.5 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.17 142309.2_18524001_2 - 2.5e-07 29.9 0.0 3.9e-05 22.6 0.0 2.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.19 142309.2_18524001_2 - 6e-05 22.5 0.0 0.00036 19.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.13 142309.2_18524001_2 - 0.0059 15.7 0.2 0.013 14.5 0.2 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.22 142309.2_18524001_2 - 0.056 13.8 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SSF PF00474.15 001144597.2_18524001_1 - 1.8e-21 76.4 27.0 2.5e-21 75.9 27.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family zf-C2H2 PF00096.24 142400.2_18525001_1 - 2.5e-18 65.3 66.2 0.00031 20.9 2.9 8.8 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 142400.2_18525001_1 - 4.3e-18 64.7 40.8 0.0006 20.0 0.1 8.1 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.4 142400.2_18525001_1 - 6.9e-12 45.0 58.8 0.0061 17.2 0.3 8.8 9 0 0 9 9 9 6 C2H2-type zinc finger zf-AD PF07776.13 142400.2_18525001_1 - 1.6e-10 40.9 2.5 1.6e-10 40.9 2.5 3.3 3 1 0 3 3 3 1 Zinc-finger associated domain (zf-AD) zf-C2H2_jaz PF12171.6 142400.2_18525001_1 - 0.00065 19.8 40.2 0.081 13.1 3.8 7.5 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 142400.2_18525001_1 - 0.0018 18.4 0.1 0.0018 18.4 0.1 7.6 8 0 0 8 8 8 2 Zinc-finger of C2H2 type HypA PF01155.17 142400.2_18525001_1 - 0.032 14.1 0.3 0.032 14.1 0.3 4.8 2 2 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.3 142400.2_18525001_1 - 0.26 11.9 30.9 0.34 11.6 1.1 5.5 3 1 2 5 5 5 0 zinc-ribbon family Ribosomal_L32p PF01783.21 142400.2_18525001_1 - 1.7 8.8 13.9 1.8 8.7 2.1 3.9 4 0 0 4 4 4 0 Ribosomal L32p protein family zf-H2C2_2 PF13465.4 142402.3_18524001_1 - 9.5e-16 57.3 42.9 1.7e-06 28.1 0.6 6.3 7 0 0 7 7 7 4 Zinc-finger double domain zf-AD PF07776.13 142402.3_18524001_1 - 2.9e-11 43.3 5.8 4.8e-11 42.6 2.7 2.8 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) zf-C2H2 PF00096.24 142402.3_18524001_1 - 5.2e-11 42.2 45.3 0.0019 18.4 4.0 5.9 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-met PF12874.5 142402.3_18524001_1 - 2e-08 34.2 4.9 2e-08 34.2 4.9 5.6 7 0 0 7 7 6 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.4 142402.3_18524001_1 - 9.8e-06 25.9 46.9 0.013 16.2 2.1 6.4 7 0 0 7 7 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 142402.3_18524001_1 - 0.00049 20.2 31.1 0.0042 17.2 4.1 5.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.10 142402.3_18524001_1 - 0.0076 16.2 0.8 0.0076 16.2 0.8 3.1 4 0 0 4 4 3 1 DBF zinc finger HypA PF01155.17 142402.3_18524001_1 - 0.024 14.5 9.9 0.41 10.5 0.3 2.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.4 142402.3_18524001_1 - 0.031 14.4 3.7 3.5 7.8 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon Zn-ribbon_8 PF09723.8 142402.3_18524001_1 - 0.043 13.8 0.8 0.043 13.8 0.8 4.5 4 1 1 5 5 4 0 Zinc ribbon domain zf-C2H2_6 PF13912.4 142402.3_18524001_1 - 0.36 10.7 31.0 1.2 9.1 0.8 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-CHCC PF10276.7 142402.3_18524001_1 - 0.39 10.7 11.0 1.1 9.2 0.6 3.9 4 0 0 4 4 4 0 Zinc-finger domain PyrI_C PF02748.13 142402.3_18524001_1 - 0.53 10.1 16.7 0.15 11.8 1.6 4.3 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-ribbon_3 PF13248.4 142402.3_18524001_1 - 2.4 7.6 8.4 11 5.5 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-HYPF PF07503.10 142402.3_18524001_1 - 3.3 7.4 7.7 0.15 11.7 0.6 2.6 2 0 0 2 2 1 0 HypF finger C2 PF00168.28 001260237.2_18529001_1 - 7.7e-31 106.3 0.0 5.2e-14 52.3 0.0 2.6 2 0 0 2 2 2 2 C2 domain PDZ PF00595.22 001260237.2_18529001_1 - 5e-06 26.7 0.2 1.4e-05 25.2 0.2 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Baculo_11_kDa PF06143.9 001260237.2_18529001_2 - 0.1 12.0 1.9 0.76 9.3 0.0 2.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family RRM_1 PF00076.20 169782.3_18529001_1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 169782.3_18529001_3 - 5.4e-16 58.0 0.0 2.1e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.3 169782.3_18529001_3 - 0.019 14.9 0.0 0.019 14.9 0.0 8.0 5 1 2 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 adh_short PF00106.23 169806.2_18524001_2 - 4.3e-29 101.3 0.2 2.1e-21 76.1 0.2 3.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.4 169806.2_18524001_2 - 1.6e-18 67.0 0.2 7.5e-12 45.2 0.1 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 169806.2_18524001_2 - 0.00023 21.0 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 169806.2_18524001_2 - 0.0037 16.6 0.0 0.0072 15.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PDZ PF00595.22 142456.4_18529001_3 - 5.6e-47 157.9 7.7 4.1e-15 55.8 0.3 4.4 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 142456.4_18529001_3 - 2.1e-13 50.3 0.4 0.0031 17.7 0.0 4.5 4 0 0 4 4 4 4 PDZ domain KIAA1430 PF13879.4 142457.3_18525001_1 - 2.6e-13 50.4 6.3 2.6e-13 50.4 6.3 2.3 2 0 0 2 2 2 1 KIAA1430 homologue adh_short PF00106.23 142460.3_18523001_2 - 7.8e-36 123.2 0.5 4.1e-35 120.9 0.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 142460.3_18523001_2 - 8.3e-27 94.1 0.2 6e-26 91.3 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 142460.3_18523001_2 - 9.5e-10 38.5 0.2 1.7e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 142460.3_18523001_2 - 0.0083 15.5 0.2 0.014 14.7 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.17 142460.3_18523001_2 - 0.028 13.7 0.1 0.055 12.7 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Tim44 PF04280.13 001032022.2_18525001_2 - 4.2e-45 153.3 0.0 1e-44 152.0 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain DUF3251 PF11622.6 001032022.2_18525001_2 - 0.25 10.9 1.4 0.42 10.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) IncA PF04156.12 001032022.2_18525001_2 - 0.54 9.9 5.2 0.96 9.1 5.2 1.4 1 0 0 1 1 1 0 IncA protein BRAP2 PF07576.10 142532.3_18524001_1 - 9.5e-28 96.2 0.0 1.9e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.17 142532.3_18524001_1 - 4.1e-22 78.2 2.7 1.2e-21 76.6 2.7 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.4 142532.3_18524001_1 - 1.6e-09 37.7 5.2 1.6e-09 37.7 5.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.4 142532.3_18524001_1 - 4e-07 29.6 4.9 4e-07 29.6 4.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 142532.3_18524001_1 - 1.8e-05 24.4 3.6 1.8e-05 24.4 3.6 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Tropomyosin PF00261.18 142532.3_18524001_1 - 2.9e-05 23.4 18.8 5.8e-05 22.4 18.8 1.4 1 0 0 1 1 1 1 Tropomyosin zf-RING_UBOX PF13445.4 142532.3_18524001_1 - 3.5e-05 23.6 0.1 3.5e-05 23.6 0.1 2.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 142532.3_18524001_1 - 4.8e-05 23.1 3.4 4.8e-05 23.1 3.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.5 142532.3_18524001_1 - 5.6e-05 23.2 4.5 5.6e-05 23.2 4.5 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 142532.3_18524001_1 - 9.6e-05 21.9 1.6 9.6e-05 21.9 1.6 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.5 142532.3_18524001_1 - 0.00084 19.2 2.1 0.0019 18.0 2.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Spc7 PF08317.9 142532.3_18524001_1 - 0.00087 18.1 21.8 0.0014 17.5 21.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-C3HC4_3 PF13920.4 142532.3_18524001_1 - 0.001 18.7 14.0 0.0058 16.3 3.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.20 142532.3_18524001_1 - 0.0089 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM167 PF11652.6 142532.3_18524001_1 - 0.033 14.5 8.0 0.67 10.3 3.1 2.6 1 1 1 2 2 2 0 FAM167 zf-RING_4 PF14570.4 142532.3_18524001_1 - 0.044 13.4 2.6 0.13 11.9 2.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tmemb_cc2 PF10267.7 142532.3_18524001_1 - 0.046 12.7 16.7 0.088 11.8 16.7 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein IncA PF04156.12 142532.3_18524001_1 - 0.093 12.4 29.9 2.5 7.7 30.2 2.1 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.7 142532.3_18524001_1 - 0.15 12.0 30.0 5.9 6.8 30.0 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4085 PF13315.4 142532.3_18524001_1 - 0.15 11.5 11.3 0.33 10.4 11.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) APG6 PF04111.10 142532.3_18524001_1 - 0.44 9.8 24.5 0.81 8.9 24.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.11 142532.3_18524001_1 - 0.63 9.1 14.1 1.2 8.1 13.8 1.7 2 0 0 2 2 1 0 TMPIT-like protein DUF342 PF03961.11 142532.3_18524001_1 - 0.75 8.2 13.9 1.1 7.7 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3584 PF12128.6 142532.3_18524001_1 - 0.94 6.8 26.0 1.3 6.3 26.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.17 142532.3_18524001_1 - 0.95 9.1 29.1 0.49 10.0 27.0 1.6 2 0 0 2 2 1 0 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.13 142532.3_18524001_1 - 1.1 8.6 13.5 2 7.7 13.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4200 PF13863.4 142532.3_18524001_1 - 1.1 9.5 30.6 1.3 9.3 18.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3496 PF12001.6 142532.3_18524001_1 - 1.3 9.3 14.9 1.9 8.8 13.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) DUF1664 PF07889.10 142532.3_18524001_1 - 1.4 8.8 12.0 0.77 9.6 7.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prok-RING_4 PF14447.4 142532.3_18524001_1 - 3.6 7.4 18.1 0.08 12.7 2.8 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Vitelline_membr PF10542.7 142532.3_18524001_2 - 0.62 9.8 15.2 0.16 11.7 0.4 3.9 4 0 0 4 4 4 0 Vitelline membrane cysteine-rich region Kazal_1 PF00050.19 142532.3_18524001_3 - 0.062 13.2 2.2 0.16 11.9 2.2 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain AMP-binding PF00501.26 142575.2_18524001_1 - 8.6e-66 222.1 0.0 1e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 142575.2_18524001_1 - 1.3e-11 45.2 0.1 2.5e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7tm_6 PF02949.18 079690.2_18523001_2 - 1.6e-55 188.2 11.7 1.6e-55 188.2 11.7 1.4 1 1 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 079690.2_18523001_2 - 1.4e-05 24.3 24.2 4.3e-05 22.7 24.2 1.7 1 1 0 1 1 1 1 7tm Chemosensory receptor zf-B_box PF00643.22 079985.4_18529001_1 - 3.7e-12 46.1 20.9 2.6e-09 37.0 8.6 4.8 5 0 0 5 5 5 2 B-box zinc finger Bromodomain PF00439.23 079985.4_18529001_1 - 7.1e-11 41.9 0.3 1.7e-10 40.7 0.3 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.27 079985.4_18529001_1 - 4.6e-07 29.5 11.1 4.6e-07 29.5 11.1 5.0 4 2 0 4 4 4 1 PHD-finger zf-RING_5 PF14634.4 079985.4_18529001_1 - 4.6e-05 23.1 5.1 4.6e-05 23.1 5.1 3.8 4 0 0 4 4 4 2 zinc-RING finger domain Tautomerase PF01361.19 079985.4_18529001_1 - 0.21 11.4 0.3 0.5 10.2 0.3 1.5 1 0 0 1 1 1 0 Tautomerase enzyme RRM_1 PF00076.20 169928.3_18526001_3 - 1.8e-45 152.4 0.4 4.9e-16 58.2 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 169928.3_18526001_3 - 8.1e-08 31.8 0.0 1.4e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 169928.3_18526001_3 - 1.4e-07 31.4 0.0 0.46 10.5 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif RRM_occluded PF16842.3 169928.3_18526001_3 - 0.00034 20.3 0.0 0.008 15.9 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.6 169928.3_18526001_3 - 0.00082 19.3 0.5 1.6 8.7 0.1 3.4 2 2 2 4 4 4 2 Limkain b1 DUF1866 PF08952.9 169928.3_18526001_3 - 0.0018 18.0 0.1 0.012 15.3 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1866) RRM_3 PF08777.9 169928.3_18526001_3 - 0.15 11.9 1.7 0.32 10.9 0.9 1.9 2 0 0 2 2 2 0 RNA binding motif Nramp PF01566.16 206529.2_18526001_2 - 5.9e-117 390.5 16.9 5.9e-117 390.5 16.9 1.8 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein 7tm_1 PF00001.19 142709.2_18529001_3 - 5.9e-54 183.0 15.7 9.7e-54 182.3 15.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 142709.2_18529001_3 - 2.3e-10 40.2 13.9 1.3e-09 37.7 13.9 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 142709.2_18529001_3 - 3.6e-09 36.2 11.6 6.6e-09 35.3 11.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 142709.2_18529001_3 - 0.00034 20.3 11.6 0.00056 19.6 11.6 1.3 1 0 0 1 1 1 1 Olfactory receptor Pkinase_Tyr PF07714.15 079712.6_18529001_1 - 7.5e-91 303.9 0.0 1.2e-90 303.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.22 079712.6_18529001_1 - 1.2e-51 173.4 0.2 4.4e-27 94.3 0.0 3.0 3 0 0 3 3 3 2 Receptor L domain Pkinase PF00069.23 079712.6_18529001_1 - 5.8e-37 127.4 0.0 1.1e-36 126.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.18 079712.6_18529001_1 - 7e-31 107.0 39.9 7e-31 107.0 39.9 3.0 2 0 0 2 2 2 1 Furin-like cysteine rich region fn3 PF00041.19 079712.6_18529001_1 - 5.5e-12 45.7 1.1 0.00055 20.1 0.0 4.8 4 0 0 4 4 4 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.3 079712.6_18529001_1 - 0.0033 17.8 0.2 3.1 8.3 0.0 3.8 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain G6B PF15096.4 079712.6_18529001_1 - 0.054 13.1 6.5 0.73 9.4 0.0 3.6 4 0 0 4 4 4 0 G6B family 7tm_7 PF08395.10 169973.1_18523001_1 - 3.2e-43 148.2 23.3 3.6e-43 148.1 23.3 1.0 1 0 0 1 1 1 1 7tm Chemosensory receptor HTH_psq PF05225.14 143745.3_18529001_2 - 4.7e-15 54.9 0.2 3.9e-14 52.0 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain 2HCT PF03390.13 143745.3_18529001_2 - 0.016 13.7 0.4 0.029 12.9 0.4 1.3 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family FAA_hydrolase PF01557.16 142745.4_18523001_1 - 1.3e-64 217.7 0.0 1.7e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SAM_2 PF07647.15 001043277.3_18529001_2 - 2.6e-27 94.6 0.0 2.1e-14 53.2 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001043277.3_18529001_2 - 1.2e-25 89.6 0.0 1.2e-14 54.3 0.0 2.9 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SH3_2 PF07653.15 001043277.3_18529001_2 - 1.5e-08 34.0 0.0 3.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001043277.3_18529001_2 - 0.0016 17.9 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain TFIIA PF03153.11 001043277.3_18529001_2 - 0.019 14.8 15.0 0.036 14.0 15.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ELO PF01151.16 142805.4_18524001_2 - 2.1e-65 220.6 21.4 2.9e-65 220.1 21.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family zf-C2H2 PF00096.24 142889.3_18529001_2 - 7.7e-09 35.4 10.7 0.00016 21.8 2.2 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 142889.3_18529001_2 - 7e-08 32.4 0.2 7e-08 32.4 0.2 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 142889.3_18529001_2 - 8.1e-05 23.0 15.1 0.016 15.8 2.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 142889.3_18529001_2 - 0.0029 17.8 8.0 0.015 15.4 1.2 3.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 142889.3_18529001_2 - 1.5 9.2 14.8 0.14 12.4 1.6 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Dscam_C PF12355.6 142889.3_18529001_3 - 7.4 7.4 14.9 4 8.3 1.6 2.7 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Ig_3 PF13927.4 142899.2_18526001_3 - 5e-06 26.9 0.0 0.4 11.2 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.4 142899.2_18526001_3 - 4.5e-05 23.6 0.1 0.034 14.3 0.0 3.4 2 2 1 3 3 3 2 Immunoglobulin domain V-set PF07686.15 142899.2_18526001_3 - 0.0029 17.6 0.1 0.022 14.8 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.10 142899.2_18526001_3 - 0.0032 17.4 0.0 0.0095 15.9 0.0 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Trypsin PF00089.24 144395.5_18524001_1 - 1.6e-30 106.5 0.0 2.1e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin CLIP PF12032.6 144395.5_18524001_1 - 0.00029 20.9 3.6 0.00059 19.9 0.3 2.4 1 1 1 2 2 2 1 Regulatory CLIP domain of proteinases Trypsin_2 PF13365.4 144395.5_18524001_1 - 0.066 13.9 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.24 142918.4_18524001_1 - 2.2e-43 148.5 0.0 4.1e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 142918.4_18524001_1 - 4.7e-05 24.2 0.0 8.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 142918.4_18524001_1 - 0.00098 19.4 0.2 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) CLIP PF12032.6 142918.4_18524001_1 - 0.0047 17.0 0.1 0.0047 17.0 0.1 4.6 3 1 1 4 4 4 2 Regulatory CLIP domain of proteinases ELO PF01151.16 170095.3_18522001_1 - 1.1e-52 179.0 26.2 1.2e-52 178.8 26.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DAGK_acc PF00609.17 206552.4_18529001_3 - 6.5e-54 182.4 0.0 1.2e-53 181.6 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain RA PF00788.21 206552.4_18529001_3 - 6e-33 113.2 0.0 1.3e-18 67.2 0.0 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.20 206552.4_18529001_3 - 9.1e-30 102.2 46.2 1.4e-12 47.2 6.5 3.5 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.22 206552.4_18529001_3 - 2e-23 82.3 0.0 4.7e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_2 PF03107.14 206552.4_18529001_3 - 0.00012 22.2 32.7 0.004 17.3 3.5 3.9 3 0 0 3 3 3 2 C1 domain TUG-UBL1 PF11470.6 206552.4_18529001_3 - 0.0062 16.7 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 1 TUG ubiquitin-like domain RRM_1 PF00076.20 206552.4_18529001_3 - 0.14 11.8 0.1 0.39 10.4 0.1 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VIT1 PF01988.17 206552.4_18529001_3 - 0.39 10.4 2.2 0.87 9.3 0.6 2.1 2 0 0 2 2 2 0 VIT family IF4E PF01652.16 176552.3_18524001_1 - 7.4e-49 165.5 0.1 1.2e-48 164.8 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DM4_12 PF07841.11 142999.2_18523001_1 - 1.8e-12 47.6 0.2 4.6e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 DM4/DM12 family DM4_12 PF07841.11 143004.3_18523001_1 - 2.6e-10 40.7 0.0 4.4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 DM4/DM12 family C2 PF00168.28 170653.3_18526001_1 - 2.1e-57 191.7 0.6 9e-20 70.8 0.1 3.4 3 0 0 3 3 3 3 C2 domain SMP_LBD PF17047.3 170653.3_18526001_1 - 3.5e-44 150.3 0.3 6.2e-44 149.5 0.3 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.7 170653.3_18526001_1 - 0.00024 20.7 0.3 1 8.9 0.0 3.3 3 0 0 3 3 3 2 N-terminal C2 in EEIG1 and EHBP1 proteins TFIIA PF03153.11 170150.2_18528001_1 - 5.5e-06 26.5 34.7 0.0042 17.0 13.5 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Herpes_LMP1 PF05297.9 170150.2_18528001_1 - 0.03 13.4 1.1 0.058 12.5 1.1 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-C2H2_4 PF13894.4 001043289.2_18529001_3 - 1.6e-08 34.5 64.2 0.024 15.3 0.5 9.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2 PF00096.24 001043289.2_18529001_3 - 2.3e-08 33.9 69.0 0.0043 17.3 1.0 8.6 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-AD PF07776.13 001043289.2_18529001_3 - 5.7e-07 29.5 0.1 5.7e-07 29.5 0.1 4.0 4 0 0 4 4 4 1 Zinc-finger associated domain (zf-AD) zf-C2H2_jaz PF12171.6 001043289.2_18529001_3 - 9.5e-07 28.8 18.0 0.0035 17.5 0.1 6.4 5 1 1 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001043289.2_18529001_3 - 0.00012 22.2 14.7 0.56 10.5 0.1 5.5 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001043289.2_18529001_3 - 0.0019 17.9 34.6 0.0051 16.6 0.9 6.8 7 0 0 7 7 7 3 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001043289.2_18529001_3 - 0.012 15.9 0.1 0.012 15.9 0.1 8.5 10 0 0 10 10 10 0 Zinc-finger double domain Ogr_Delta PF04606.10 001043289.2_18529001_3 - 0.022 14.6 1.5 0.13 12.1 1.5 2.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.3 001043289.2_18529001_3 - 0.99 9.1 29.1 0.022 14.4 3.4 5.6 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-Di19 PF05605.10 001043289.2_18529001_3 - 6 7.1 25.2 0.61 10.3 6.4 4.7 2 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding ALMT PF11744.6 170166.3_18525001_3 - 5.5 5.6 10.8 7.5 5.1 10.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5040 PF16443.3 143030.3_18523001_2 - 0.06 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) Nicastrin PF05450.13 206568.4_18526001_1 - 1.8e-94 315.4 0.2 2.6e-94 314.9 0.2 1.2 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.15 206568.4_18526001_1 - 3.8e-10 39.7 0.0 5.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 C2 PF00168.28 001104439.3_18528001_1 - 7.3e-33 112.8 0.0 2.6e-17 62.9 0.0 3.2 2 1 0 2 2 2 2 C2 domain Membr_traf_MHD PF10540.7 001104439.3_18528001_1 - 3.3e-05 24.1 1.6 0.00031 20.9 0.9 2.8 1 1 1 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain Spore_III_AB PF09548.8 001104439.3_18528001_1 - 0.027 14.5 4.7 0.26 11.3 1.2 3.1 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) CEP76-C2 PF15627.4 001104439.3_18528001_1 - 0.073 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 CEP76 C2 domain Pkinase_Tyr PF07714.15 143092.3_18526001_3 - 7e-95 317.1 0.0 9.8e-95 316.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 143092.3_18526001_3 - 5.4e-46 156.9 0.0 8.1e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cadherin PF00028.15 143092.3_18526001_3 - 0.0015 18.8 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 Cadherin domain APH PF01636.21 143092.3_18526001_3 - 0.068 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Iso_dh PF00180.18 143159.3_18523001_3 - 2.4e-65 220.8 0.6 3.4e-65 220.3 0.6 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Gb3_synth PF04572.10 143177.4_18524001_2 - 1.6e-43 147.9 2.5 1.9e-43 147.7 1.1 1.8 2 0 0 2 2 2 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.13 143177.4_18524001_2 - 5.5e-19 68.5 0.0 1.9e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3068 PF11271.6 143177.4_18524001_2 - 0.18 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) Abhydro_lipase PF04083.14 170249.2_18523001_1 - 1.4e-22 78.9 0.1 2.6e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.18 170249.2_18523001_1 - 1.1e-13 51.4 1.3 5.6e-13 49.0 1.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 170249.2_18523001_1 - 0.00078 18.7 0.1 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.5 170249.2_18523001_1 - 0.023 15.2 1.4 0.032 14.7 1.4 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PNP_UDP_1 PF01048.18 170296.3_18524001_1 - 1.6e-32 112.5 0.0 1.9e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3783 PF12646.5 170296.3_18524001_1 - 0.035 13.9 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Aldedh PF00171.20 170304.2_18524001_3 - 5e-178 592.2 0.1 5.6e-178 592.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.9 170304.2_18524001_3 - 0.15 11.3 0.0 0.95 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SPT2 PF08243.9 143280.3_18525001_3 - 1.2e-21 77.2 11.3 1.2e-21 77.2 11.3 4.5 4 0 0 4 4 4 1 SPT2 chromatin protein Choline_kinase PF01633.18 143280.3_18525001_3 - 0.1 12.1 3.6 0.25 10.7 3.6 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase NTP_transf_5 PF14907.4 143280.3_18525001_3 - 0.21 11.0 0.7 0.41 10.1 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase DDE_Tnp_1_assoc PF13808.4 079808.4_18529001_2 - 0.087 12.7 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-associated Kinesin PF00225.21 079808.4_18529001_3 - 4.3e-109 364.3 0.0 9.3e-109 363.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.3 079808.4_18529001_3 - 1e-25 90.3 0.0 2.6e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding PX PF00787.22 079808.4_18529001_3 - 2.9e-10 40.0 0.1 1.4e-09 37.8 0.1 2.1 1 0 0 1 1 1 1 PX domain Kinesin_assoc PF16183.3 079808.4_18529001_3 - 0.0027 17.8 0.7 0.0027 17.8 0.7 4.9 4 2 2 6 6 6 2 Kinesin-associated DUF724 PF05266.12 079808.4_18529001_3 - 0.0061 16.3 9.4 0.0061 16.3 9.4 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF724) Yop-YscD_cpl PF16697.3 079808.4_18529001_3 - 0.0071 16.5 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MBF2 PF15868.3 143315.2_18524001_2 - 0.022 15.1 0.0 10 6.6 0.1 2.5 2 0 0 2 2 2 0 Transcription activator MBF2 DUF4786 PF16027.3 143323.4_18524001_3 - 9e-58 195.5 7.0 1.3e-57 195.0 7.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4786) RRM_1 PF00076.20 143352.4_18525001_2 - 2.6e-35 119.9 0.0 1.4e-20 72.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 143352.4_18525001_2 - 0.0043 16.8 0.0 0.076 12.8 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.3 143352.4_18525001_2 - 0.075 13.0 6.7 1.3 9.1 0.0 3.7 3 1 0 3 3 3 0 RNA recognition motif RRM_3 PF08777.9 143352.4_18525001_2 - 0.15 11.9 0.0 0.15 11.9 0.0 3.3 4 0 0 4 4 4 0 RNA binding motif Ndc1_Nup PF09531.8 143352.4_18525001_2 - 0.37 9.3 22.3 0.57 8.7 22.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3700 PF12481.6 143352.4_18525001_2 - 1 8.6 5.0 1.5 8.0 2.8 2.2 2 0 0 2 2 2 0 Aluminium induced protein Glycos_transf_2 PF00535.24 143373.3_18526001_3 - 2.9e-24 85.6 0.0 5e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.20 143373.3_18526001_3 - 6.4e-12 45.7 0.6 9.7e-12 45.1 0.6 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.12 143373.3_18526001_3 - 6e-10 38.5 0.0 1.2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.7 143373.3_18526001_3 - 2.5e-05 23.7 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GlcNAc PF11397.6 143373.3_18526001_3 - 0.0033 16.8 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) Glyco_tranf_2_3 PF13641.4 143373.3_18526001_3 - 0.0038 17.0 0.0 0.018 14.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF1248 PF06852.10 143373.3_18526001_3 - 0.015 14.7 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) DHR-2 PF06920.11 001144646.2_18529001_3 - 4.1e-94 316.0 1.3 4.1e-94 316.0 1.3 1.7 2 0 0 2 2 2 1 Dock homology region 2 DOCK_N PF16172.3 001144646.2_18529001_3 - 2.1e-83 280.2 0.0 4.4e-83 279.1 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.4 001144646.2_18529001_3 - 2.5e-47 161.0 0.0 5.4e-47 160.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Lin-8 PF03353.13 001144646.2_18529001_3 - 0.015 14.8 4.9 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Saw1 PF11561.6 001144646.2_18529001_3 - 0.026 13.9 0.5 0.05 13.0 0.5 1.4 1 0 0 1 1 1 0 Single strand annealing-weakened 1 PI3K_C2 PF00792.22 001144646.2_18529001_3 - 0.094 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Pkinase PF00069.23 001014678.3_18529001_1 - 7.3e-50 169.6 0.5 9.9e-50 169.2 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001014678.3_18529001_1 - 1.5e-20 73.4 0.2 2.8e-20 72.6 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001104491.3_18525001_3 - 2.4e-50 171.2 0.5 3.2e-50 170.8 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001104491.3_18525001_3 - 5.4e-21 74.9 0.2 1e-20 74.0 0.2 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase ABC_membrane PF00664.21 170399.2_18529001_3 - 5.4e-56 190.1 25.4 2e-32 112.8 9.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 170399.2_18529001_3 - 4.7e-51 172.8 0.0 4.2e-29 101.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.17 170399.2_18529001_3 - 6.4e-11 42.0 2.8 0.0056 16.0 0.0 4.4 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.21 170399.2_18529001_3 - 1.2e-06 28.4 0.1 0.06 13.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.14 170399.2_18529001_3 - 1.8e-06 27.9 0.0 0.0063 16.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.4 170399.2_18529001_3 - 1.4e-05 24.5 0.2 0.077 12.6 0.0 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain Dynamin_N PF00350.21 170399.2_18529001_3 - 7.4e-05 22.7 2.1 0.011 15.7 0.2 2.6 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.4 170399.2_18529001_3 - 0.00035 20.4 0.2 2.2 7.9 0.0 3.7 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.4 170399.2_18529001_3 - 0.00088 19.7 1.7 0.13 12.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.15 170399.2_18529001_3 - 0.0013 18.7 0.1 0.057 13.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.4 170399.2_18529001_3 - 0.0036 17.4 0.1 3.6 7.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.4 170399.2_18529001_3 - 0.0039 17.4 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.15 170399.2_18529001_3 - 0.0053 16.4 0.0 1.3 8.6 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.20 170399.2_18529001_3 - 0.0081 16.4 0.8 5.7 7.3 0.0 3.9 3 1 1 4 4 4 1 RNA helicase DUF815 PF05673.11 170399.2_18529001_3 - 0.012 14.6 0.1 0.059 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IIGP PF05049.11 170399.2_18529001_3 - 0.014 14.4 0.3 0.33 9.8 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.4 170399.2_18529001_3 - 0.035 13.7 0.0 0.56 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain IgG_binding_B PF01378.15 170399.2_18529001_3 - 0.041 13.8 0.1 0.091 12.7 0.1 1.5 1 0 0 1 1 1 0 B domain AAA_15 PF13175.4 170399.2_18529001_3 - 0.045 13.2 0.4 10 5.5 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.10 170399.2_18529001_3 - 0.061 12.5 0.2 4.7 6.3 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.4 170399.2_18529001_3 - 0.1 12.2 0.0 22 4.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Roc PF08477.11 170399.2_18529001_3 - 0.1 12.7 0.1 4.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.14 170399.2_18529001_3 - 0.64 9.2 4.2 3 7.0 0.0 2.9 3 0 0 3 3 3 0 AIG1 family Calreticulin PF00262.16 001043301.2_18526001_3 - 2.5e-162 539.8 11.8 3.4e-162 539.3 11.8 1.2 1 0 0 1 1 1 1 Calreticulin family DUF4381 PF14316.4 001043301.2_18526001_3 - 0.0082 16.3 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Connexin PF00029.17 001043301.2_18526001_3 - 0.16 11.6 3.6 0.7 9.5 3.7 1.9 1 1 0 1 1 1 0 Connexin DUF1510 PF07423.9 001043301.2_18526001_3 - 0.26 10.6 10.5 0.07 12.4 7.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Presenilin PF01080.15 001043301.2_18526001_3 - 3 6.4 8.8 5 5.6 8.8 1.2 1 0 0 1 1 1 0 Presenilin SPC12 PF06645.11 176583.3_18521001_2 - 8.3e-27 93.0 0.7 1.2e-26 92.5 0.7 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Arm PF00514.21 143469.2_18527001_2 - 1.5e-09 37.4 0.8 0.017 15.0 0.1 6.4 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat BTB PF00651.29 143469.2_18527001_2 - 1.3e-07 31.6 0.2 9e-07 29.0 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain V-ATPase_H_N PF03224.12 143469.2_18527001_2 - 0.00036 19.8 3.5 0.005 16.0 0.5 2.7 2 1 0 2 2 2 1 V-ATPase subunit H Sec7_N PF12783.5 143469.2_18527001_2 - 0.0048 16.7 7.9 0.034 14.0 2.5 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Arm_2 PF04826.11 143469.2_18527001_2 - 0.019 14.3 0.5 0.09 12.1 0.6 2.1 2 0 0 2 2 2 0 Armadillo-like RasGEF_N_2 PF14663.4 143469.2_18527001_2 - 0.067 13.4 0.6 3.5 7.9 0.1 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_2 PF13646.4 143469.2_18527001_2 - 0.093 13.0 0.2 1.9 8.8 0.0 3.4 5 0 0 5 5 5 0 HEAT repeats RICTOR_V PF14668.4 143469.2_18527001_2 - 0.1 12.7 2.6 0.56 10.3 0.3 3.3 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Reprolysin_5 PF13688.4 170455.3_18525001_3 - 7.2e-36 124.1 0.0 1.4e-35 123.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.4 170455.3_18525001_3 - 7e-34 117.3 0.0 1.3e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.3 170455.3_18525001_3 - 2.7e-18 66.0 13.9 2.7e-18 66.0 13.9 4.1 4 1 0 4 4 4 1 Membrane-proximal domain, switch, for ADAM17 Reprolysin_3 PF13582.4 170455.3_18525001_3 - 4.9e-13 49.6 0.0 9.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.21 170455.3_18525001_3 - 2e-12 47.6 27.3 2e-12 47.6 27.3 3.1 2 1 0 2 2 2 1 Disintegrin Pep_M12B_propep PF01562.17 170455.3_18525001_3 - 2.2e-09 37.5 0.7 4e-09 36.7 0.3 1.6 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.17 170455.3_18525001_3 - 2.8e-05 24.0 6.6 0.00019 21.3 0.0 3.2 4 0 0 4 4 4 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.4 170455.3_18525001_3 - 0.00024 20.7 0.0 0.00075 19.1 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EIIC-GAT PF03611.12 170455.3_18525001_3 - 0.045 12.7 0.1 0.067 12.1 0.1 1.1 1 0 0 1 1 1 0 PTS system sugar-specific permease component Peptidase_M10 PF00413.22 170455.3_18525001_3 - 0.074 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Matrixin Homeobox PF00046.27 001144658.2_18527001_2 - 6e-22 77.1 8.6 1e-21 76.4 8.6 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.15 001144658.2_18527001_2 - 1.9e-06 27.3 2.9 5e-06 26.0 2.9 1.8 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.9 001144658.2_18527001_2 - 0.0038 17.0 0.5 0.014 15.1 0.5 2.0 1 0 0 1 1 1 1 Homeobox KN domain G-patch PF01585.21 143594.3_18523001_2 - 2.1e-12 46.6 0.1 2.1e-12 46.6 0.1 3.7 4 0 0 4 4 4 1 G-patch domain G-patch_2 PF12656.5 143594.3_18523001_2 - 0.00018 21.4 0.3 0.00018 21.4 0.3 3.5 3 1 0 3 3 3 1 G-patch domain Cytochrom_B558a PF05038.11 143594.3_18523001_2 - 0.11 11.9 3.9 0.18 11.2 3.9 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit SSF PF00474.15 143632.4_18525001_1 - 8.7e-37 126.8 27.8 8.7e-37 126.8 27.8 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family RRM_5 PF13893.4 170582.4_18527001_3 - 5.3e-45 151.9 3.2 1.6e-31 108.3 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 170582.4_18527001_3 - 7.3e-26 89.7 0.0 1.5e-07 30.9 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox PF00046.27 206448.1_18529001_3 - 1.1e-20 73.0 8.1 2.9e-20 71.7 8.1 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.27 206453.1_18529001_2 - 9.4e-21 73.3 8.1 2.8e-20 71.8 8.1 1.9 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.27 206443.2_18528001_1 - 4.4e-21 74.3 9.4 1.1e-20 73.1 9.4 1.7 1 0 0 1 1 1 1 Homeobox domain TFIIA PF03153.11 206443.2_18528001_1 - 0.13 12.1 24.2 0.017 15.0 18.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.7 206443.2_18528001_1 - 4.6 5.6 9.0 6.5 5.0 9.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Carn_acyltransf PF00755.18 001300266.1_18525001_2 - 5.7e-177 589.7 0.0 6.6e-177 589.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase 7tm_1 PF00001.19 169011.3_18528001_1 - 7.6e-64 215.4 0.2 1.1e-63 214.9 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 169011.3_18528001_1 - 4.8e-06 26.0 12.4 0.00032 20.0 4.3 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Med31 PF05669.10 141226.4_18523001_1 - 1.1e-37 127.8 8.3 1.1e-37 127.8 8.3 1.7 2 0 0 2 2 2 1 SOH1 K_channel_TID PF07941.9 141226.4_18523001_3 - 3.1 8.2 10.4 0.51 10.7 6.2 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain SNF5 PF04855.10 169055.3_18523001_2 - 2.5e-55 187.7 0.4 7e-29 101.1 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 zf-HC5HC2H_2 PF13832.4 001275400.1_18529001_2 - 2.5e-32 111.2 18.1 9.4e-31 106.1 9.8 2.4 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.4 001275400.1_18529001_2 - 5.9e-22 77.6 25.0 1.6e-21 76.2 9.3 3.3 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.4 001275400.1_18529001_2 - 2.5e-13 49.2 3.9 2.5e-13 49.2 3.9 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.27 001275400.1_18529001_2 - 2.2e-07 30.5 9.3 2.2e-07 30.5 9.3 3.0 2 1 0 2 2 2 1 PHD-finger zf-RING-like PF08746.9 001275400.1_18529001_2 - 6.2 7.1 17.9 4.9 7.4 6.2 3.2 2 1 0 2 2 2 0 RING-like domain ATP-synt_F PF01990.15 001260014.1_18522001_3 - 2e-28 98.4 0.1 2.5e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Kazal_1 PF00050.19 141360.2_18525001_3 - 2.3e-10 40.2 26.4 1.4e-05 24.9 0.0 5.3 5 1 0 5 5 5 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 141360.2_18525001_3 - 1.7e-08 34.3 20.6 0.017 15.2 1.0 5.6 5 0 0 5 5 5 4 Kazal-type serine protease inhibitor domain zf-HC5HC2H_2 PF13832.4 141360.2_18525001_3 - 3.7 7.6 13.6 0.74 9.9 3.7 3.2 3 0 0 3 3 3 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.4 141360.2_18525001_3 - 9.4 6.4 15.3 0.54 10.4 3.2 3.4 3 0 0 3 3 3 0 PHD-like zinc-binding domain Gelsolin PF00626.20 080126.4_18526001_2 - 6.2e-71 234.2 3.1 3.4e-14 52.4 0.0 6.1 6 1 0 6 6 6 5 Gelsolin repeat PBP_GOBP PF01395.20 057642.3_18522001_2 - 1.1e-11 44.8 0.9 1.7e-11 44.2 0.9 1.3 1 0 0 1 1 1 1 PBP/GOBP family LSM PF01423.20 141388.4_18522001_2 - 1.1e-18 66.6 0.7 1.6e-18 66.0 0.7 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.1 141388.4_18522001_2 - 0.027 14.0 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 Hfq protein Reticulon PF02453.15 001260035.1_18522001_3 - 2.2e-35 121.8 3.8 3.3e-35 121.2 3.8 1.3 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.9 001260035.1_18522001_3 - 0.013 14.3 0.5 0.77 8.5 0.8 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DNA_binding_1 PF01035.18 001316493.1_18523001_1 - 4.9e-24 84.1 0.1 9.3e-24 83.2 0.1 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain RRM_1 PF00076.20 001276193.1_18524001_2 - 5.8e-12 45.1 0.1 1.1e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Leo1 PF04004.11 079516.3_18525001_3 - 7.4e-53 178.7 0.8 7.4e-53 178.7 0.8 2.4 2 0 0 2 2 2 1 Leo1-like protein AA_permease_2 PF13520.4 001276210.1_18526001_2 - 2.2e-52 178.2 48.0 3.1e-52 177.7 48.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.19 001276210.1_18526001_2 - 4.4e-24 84.8 44.5 6.7e-24 84.2 44.5 1.1 1 0 0 1 1 1 1 Amino acid permease ATP-synt_C PF00137.19 001260454.1_18523001_2 - 2.3e-10 40.5 12.2 4.5e-10 39.6 12.2 1.5 1 0 0 1 1 1 1 ATP synthase subunit C MH2 PF03166.12 170559.3_18527001_3 - 3.7e-76 255.3 0.1 4.1e-75 252.0 0.0 2.1 2 0 0 2 2 2 1 MH2 domain MH1 PF03165.14 170559.3_18527001_3 - 1e-38 131.5 0.2 2.3e-38 130.4 0.2 1.6 1 0 0 1 1 1 1 MH1 domain DUF2722 PF10846.6 170559.3_18527001_3 - 0.26 10.0 11.1 0.083 11.7 7.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.6 170559.3_18527001_3 - 3.8 6.9 25.6 1.2 8.5 17.1 2.4 2 0 0 2 2 2 0 Spt20 family BTB PF00651.29 001202400.1_18528001_2 - 6.4e-26 90.6 0.1 1.2e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.24 001202400.1_18528001_2 - 3.4e-06 27.1 9.5 0.00058 20.1 0.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001202400.1_18528001_2 - 0.00051 20.5 0.8 0.00051 20.5 0.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.10 001202400.1_18528001_2 - 0.027 14.6 1.9 0.076 13.2 1.9 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.6 001202400.1_18528001_2 - 0.06 13.5 0.0 0.06 13.5 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001202400.1_18528001_2 - 0.11 12.4 4.8 0.26 11.2 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001202400.1_18528001_2 - 0.18 12.2 7.3 0.15 12.4 3.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain AT_hook PF02178.17 001202400.1_18528001_2 - 0.42 10.5 5.3 1.5 8.8 5.3 2.0 1 0 0 1 1 1 0 AT hook motif TBCA PF02970.14 143628.3_18522001_2 - 1.1e-23 83.3 5.9 1.5e-23 82.7 5.9 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A PP2C PF00481.19 170419.3_18526001_3 - 2e-77 260.2 0.0 2.8e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.11 170419.3_18526001_3 - 3.2e-24 85.0 0.0 8.7e-24 83.6 0.0 1.8 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C PF00481.19 170417.3_18525001_2 - 1.6e-77 260.5 0.0 2.1e-77 260.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.11 170417.3_18525001_2 - 3.7e-24 84.8 0.0 7.2e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain Pkinase PF00069.23 079821.4_18529001_2 - 4.6e-66 222.8 0.0 6.8e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 079821.4_18529001_2 - 4.1e-36 124.5 0.0 6.6e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.20 079821.4_18529001_2 - 1.4e-32 111.2 23.2 1e-16 60.4 8.3 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.28 079821.4_18529001_2 - 3e-15 56.2 0.1 6.7e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.22 079821.4_18529001_2 - 7.7e-08 32.8 0.2 1.8e-07 31.6 0.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.14 079821.4_18529001_2 - 0.011 15.9 14.5 0.19 11.9 3.0 3.0 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.3 079821.4_18529001_2 - 1.1 9.3 11.5 0.4 10.7 2.6 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger FYVE_2 PF02318.14 079821.4_18529001_2 - 1.4 9.1 12.2 4.1 7.5 1.7 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.19 079821.4_18529001_2 - 2.2 8.4 10.8 5.6 7.0 0.9 3.0 2 0 0 2 2 2 0 FYVE zinc finger PHD PF00628.27 079821.4_18529001_2 - 2.5 7.9 21.1 1.5 8.6 5.4 3.0 3 0 0 3 3 3 0 PHD-finger PHD_2 PF13831.4 079821.4_18529001_2 - 4.4 6.8 14.7 1.4 8.3 2.0 2.9 2 0 0 2 2 2 0 PHD-finger DZR PF12773.5 079821.4_18529001_2 - 7 6.6 14.4 4.5 7.3 3.9 2.7 2 0 0 2 2 2 0 Double zinc ribbon Reprolysin_5 PF13688.4 001300661.1_18529001_3 - 2.4e-28 99.5 0.1 2.4e-28 99.5 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.4 001300661.1_18529001_3 - 6.6e-26 91.3 0.0 1.3e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.4 001300661.1_18529001_3 - 3.3e-19 69.5 0.0 3.3e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.21 001300661.1_18529001_3 - 2.2e-12 47.5 25.0 2.2e-12 47.5 25.0 4.3 4 0 0 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.17 001300661.1_18529001_3 - 7.9e-09 35.7 0.4 1.7e-08 34.7 0.4 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.17 001300661.1_18529001_3 - 6e-07 29.4 0.2 5.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.4 001300661.1_18529001_3 - 5e-05 22.9 0.3 0.00026 20.6 0.3 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADH_N PF08240.10 058000.3_18523001_1 - 2.5e-29 101.2 0.6 4.5e-29 100.4 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.24 058000.3_18523001_1 - 1.4e-20 73.4 0.7 2e-20 72.9 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.3 058000.3_18523001_1 - 8.7e-11 41.6 1.8 2.2e-10 40.3 1.8 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.4 058000.3_18523001_1 - 1.2e-05 26.2 0.1 2.4e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.12 058000.3_18523001_1 - 0.0022 17.2 0.6 0.47 9.5 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.19 058000.3_18523001_1 - 0.0059 15.8 0.7 0.0059 15.8 0.7 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.25 058000.3_18523001_1 - 0.022 15.2 0.4 3.4 8.2 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.17 058000.3_18523001_1 - 0.04 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.19 058000.3_18523001_1 - 0.11 11.7 0.8 0.22 10.7 0.8 1.4 1 0 0 1 1 1 0 ThiF family Methyltransf_16 PF10294.7 058000.3_18523001_1 - 0.15 11.6 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Ala_racemase_N PF01168.18 001300673.1_18524001_3 - 1.8e-21 76.7 0.0 2.4e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3775 PF12616.6 001170063.1_18525001_2 - 0.64 9.9 4.6 2.6 8.0 3.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3775) Pkinase PF00069.23 170536.3_18527001_1 - 3.5e-26 92.0 0.0 4.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 170536.3_18527001_1 - 8.8e-17 61.1 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 170536.3_18527001_1 - 0.0011 18.9 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4603 PF15376.4 170536.3_18527001_2 - 4.8 4.3 11.8 6.7 3.8 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Ndr PF03096.12 001170048.1_18523001_1 - 4e-71 238.9 0.1 5.7e-71 238.4 0.1 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.18 001170048.1_18523001_1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001170048.1_18523001_1 - 0.15 11.1 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.23 001275353.1_18529001_2 - 8.9e-52 175.9 0.0 3.2e-37 128.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.15 001275353.1_18529001_2 - 1e-32 113.3 0.0 4.3e-24 85.0 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.19 001275353.1_18529001_2 - 2.5e-07 30.2 0.2 0.0015 18.3 0.0 4.2 5 0 0 5 5 5 1 PQQ enzyme repeat Kinase-like PF14531.4 001275353.1_18529001_2 - 2.2e-05 23.8 0.0 0.0017 17.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PQQ_2 PF13360.4 001275353.1_18529001_2 - 0.00035 20.1 0.1 0.026 14.0 0.1 2.9 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.12 001275353.1_18529001_2 - 0.0025 17.1 0.1 0.0046 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_3 PF13570.4 001275353.1_18529001_2 - 0.0059 16.9 0.0 3.7 8.0 0.0 3.1 3 0 0 3 3 3 1 PQQ-like domain PI3K_1B_p101 PF10486.7 001275353.1_18529001_2 - 0.15 9.6 8.8 0.3 8.7 8.8 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit APH PF01636.21 001275353.1_18529001_2 - 1 9.1 3.8 0.43 10.3 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family RAMP4 PF06624.10 001275367.1_18527001_3 - 0.31 11.0 1.9 1.8 8.5 1.9 2.4 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 EF-hand_7 PF13499.4 001275366.1_18523001_2 - 1.2e-16 60.7 2.3 3.7e-10 40.0 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001275366.1_18523001_2 - 1.1e-12 46.7 1.1 1.6e-06 27.5 0.2 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.30 001275366.1_18523001_2 - 6e-11 41.0 3.1 7e-06 25.1 0.6 4.0 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.4 001275366.1_18523001_2 - 4.6e-06 25.8 1.1 0.00035 19.8 0.2 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.4 001275366.1_18523001_2 - 7e-05 22.4 5.3 0.00018 21.1 0.7 3.4 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001275366.1_18523001_2 - 0.00018 21.6 1.2 0.044 14.0 0.3 2.4 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF4780 PF16012.3 001300680.1_18524001_3 - 9.9e-41 139.0 0.2 1.5e-40 138.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4780) U-box PF04564.13 143533.3_18526001_2 - 1.4e-26 92.4 0.0 2.8e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.4 143533.3_18526001_2 - 0.053 13.3 8.6 0.13 12.0 8.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.23 143533.3_18526001_2 - 1.5 8.6 8.6 4.3 7.2 8.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trypsin PF00089.24 143542.2_18522001_2 - 2.4e-47 161.5 4.3 2.8e-47 161.2 4.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 143542.2_18522001_2 - 2.4e-07 31.6 0.3 4.4e-07 30.8 0.3 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 143542.2_18522001_2 - 0.029 14.6 0.6 0.068 13.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) Pribosyl_synth PF14572.4 001202397.2_18524001_2 - 1.3e-98 328.4 1.1 1.8e-98 327.9 1.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.4 001202397.2_18524001_2 - 7.2e-37 125.7 0.2 1.5e-36 124.7 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.25 001202397.2_18524001_2 - 8.3e-06 25.3 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UN_NPL4 PF11543.6 001202397.2_18524001_2 - 0.098 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Tubulin PF00091.23 079540.6_18524001_3 - 6.8e-68 228.6 0.0 9.3e-68 228.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 079540.6_18524001_3 - 6.7e-51 171.6 0.0 1.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 079540.6_18524001_3 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain SUIM_assoc PF16619.3 001259992.2_18528001_1 - 0.011 15.7 0.5 0.011 15.7 0.5 9.9 6 2 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 V_ATPase_I PF01496.17 001259992.2_18528001_1 - 9.6 3.8 40.8 0.18 9.5 12.5 2.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Mito_carr PF00153.25 141474.3_18524001_2 - 7.4e-66 218.0 2.1 1.1e-21 76.4 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein Arrestin_N PF00339.27 141480.2_18524001_3 - 2.3e-40 137.9 1.8 1.1e-39 135.8 0.1 2.3 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 141480.2_18524001_3 - 2.1e-20 73.4 0.9 4.3e-20 72.3 0.1 1.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain zf-C2H2_4 PF13894.4 001260044.2_18525001_2 - 2e-13 49.8 17.2 3.8e-05 24.0 0.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.24 001260044.2_18525001_2 - 4.8e-11 42.4 19.2 0.00031 20.9 0.6 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 001260044.2_18525001_2 - 1e-06 28.7 18.8 0.0043 17.2 1.2 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001260044.2_18525001_2 - 0.00053 20.1 13.7 0.0074 16.5 0.2 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001260044.2_18525001_2 - 0.0019 18.0 21.2 0.11 12.3 3.8 4.0 3 1 0 3 3 3 3 C2H2-type zinc finger zf-CSL PF05207.11 001260044.2_18525001_2 - 0.046 13.3 0.2 0.092 12.4 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger zf-C2H2_9 PF16293.3 001260044.2_18525001_2 - 0.079 12.7 0.7 0.17 11.6 0.4 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.3 001260044.2_18525001_2 - 0.11 12.2 0.3 0.11 12.2 0.3 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-FCS PF06467.12 001260044.2_18525001_2 - 0.49 10.3 7.0 6.8 6.6 1.0 3.2 1 1 2 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_5 PF13909.4 001260044.2_18525001_2 - 0.51 10.0 12.9 4.5 7.0 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.5 001260044.2_18525001_2 - 1.5 9.1 14.4 1.1 9.5 1.9 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.10 001260044.2_18525001_2 - 4 7.7 10.5 23 5.3 0.1 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.19 001260044.2_18525001_2 - 6.4 6.9 12.5 2.1e+02 2.0 12.5 2.4 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2 PF00096.24 001260044.2_18525001_3 - 3.1e-14 52.4 37.5 5.4e-05 23.3 2.2 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-AD PF07776.13 001260044.2_18525001_3 - 9.3e-13 48.1 0.4 9.3e-13 48.1 0.4 2.6 3 0 0 3 3 2 1 Zinc-finger associated domain (zf-AD) zf-C2H2_4 PF13894.4 001260044.2_18525001_3 - 1.1e-11 44.3 36.7 0.00053 20.5 1.0 5.1 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001260044.2_18525001_3 - 5.5e-05 23.3 30.5 0.0028 17.9 0.2 5.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-H2C2_5 PF13909.4 001260044.2_18525001_3 - 0.00063 19.3 2.7 0.00063 19.3 2.7 4.5 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.4 001260044.2_18525001_3 - 0.0022 17.8 33.6 0.012 15.4 4.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-HIT PF04438.14 001260044.2_18525001_3 - 0.013 15.2 3.6 0.013 15.2 3.6 3.9 4 0 0 4 4 4 0 HIT zinc finger ATPase-cat_bd PF12156.6 001260044.2_18525001_3 - 0.064 13.9 0.8 0.064 13.9 0.8 3.0 3 0 0 3 3 2 0 Putative metal-binding domain of cation transport ATPase zf-Di19 PF05605.10 001260044.2_18525001_3 - 0.29 11.3 21.7 0.58 10.4 1.4 3.7 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.5 001260044.2_18525001_3 - 0.61 10.4 20.8 0.063 13.6 3.5 4.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.3 001260044.2_18525001_3 - 8.1 6.9 24.5 6.7 7.1 3.9 4.7 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.6 001260044.2_18525001_3 - 8.2 6.7 33.8 0.081 13.1 2.2 5.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding AI-2E_transport PF01594.14 001275430.1_18527001_1 - 1e-05 24.8 14.3 1e-05 24.8 14.3 4.8 5 0 0 5 5 5 3 AI-2E family transporter DUF1620 PF07774.11 141490.2_18527001_1 - 8e-73 244.5 0.0 1.2e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.4 141490.2_18527001_1 - 5.5e-05 22.7 0.2 0.092 12.2 0.3 3.7 3 1 0 3 3 3 2 PQQ-like domain DUF4443 PF14544.4 141490.2_18527001_1 - 0.044 13.6 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4443) Forkhead PF00250.16 206483.3_18528001_1 - 6.8e-25 87.1 0.1 2.4e-24 85.3 0.1 1.9 1 0 0 1 1 1 1 Forkhead domain FOXO-TAD PF16676.3 206483.3_18528001_1 - 0.027 14.7 0.5 0.058 13.7 0.5 1.5 1 0 0 1 1 1 0 Transactivation domain of FOXO protein family CPSF100_C PF13299.4 206483.3_18528001_1 - 6.6 6.7 9.2 3.3 7.7 5.6 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal zf-C2H2 PF00096.24 141875.3_18524001_1 - 1.4e-34 116.4 57.1 1.5e-05 25.1 2.2 8.8 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 141875.3_18524001_1 - 2.3e-31 106.7 49.2 1.5e-07 31.4 0.7 9.6 9 1 0 9 9 8 5 Zinc-finger double domain zf-C2H2_4 PF13894.4 141875.3_18524001_1 - 7e-26 88.5 56.8 0.00026 21.4 2.3 9.1 9 0 0 9 9 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.4 141875.3_18524001_1 - 4.6e-12 45.4 44.8 4.2e-05 23.2 0.2 8.9 8 0 0 8 8 8 5 C2H2-type zinc finger zf-AD PF07776.13 141875.3_18524001_1 - 5.1e-12 45.7 2.4 3e-11 43.3 0.2 3.2 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) zf-C2H2_jaz PF12171.6 141875.3_18524001_1 - 2.4e-10 40.3 33.4 0.0052 16.9 0.2 7.4 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.5 141875.3_18524001_1 - 1.8e-07 31.3 32.6 0.015 15.5 1.7 7.9 2 1 5 7 7 7 6 C2H2 type zinc-finger (2 copies) zf-met PF12874.5 141875.3_18524001_1 - 1.4e-05 25.2 39.4 0.12 12.7 0.3 8.0 8 0 0 8 8 7 3 Zinc-finger of C2H2 type DUF3268 PF11672.6 141875.3_18524001_1 - 0.003 17.8 5.8 0.36 11.0 0.8 3.5 3 0 0 3 3 3 2 zinc-finger-containing domain zf-Di19 PF05605.10 141875.3_18524001_1 - 0.016 15.3 1.7 0.016 15.3 1.7 7.1 5 1 3 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.3 141875.3_18524001_1 - 0.051 14.2 25.4 0.49 11.1 1.3 5.9 3 1 2 5 5 5 0 zinc-ribbon family C1_4 PF07975.10 141875.3_18524001_1 - 0.074 13.2 23.9 0.47 10.6 1.9 6.4 5 1 1 6 6 6 0 TFIIH C1-like domain CpXC PF14353.4 141875.3_18524001_1 - 0.16 11.9 19.5 0.26 11.2 0.0 6.5 4 2 1 6 6 6 0 CpXC protein BolA PF01722.16 141875.3_18524001_1 - 0.27 11.4 3.2 2.9 8.1 0.1 3.8 3 1 1 4 4 4 0 BolA-like protein PRP21_like_P PF12230.6 141875.3_18524001_1 - 0.74 9.5 9.1 1.3 8.7 0.1 3.4 3 1 1 4 4 4 0 Pre-mRNA splicing factor PRP21 like protein zf-C2HC_2 PF13913.4 141875.3_18524001_1 - 1.2 9.0 40.9 0.23 11.3 0.3 7.9 8 0 0 8 8 8 0 zinc-finger of a C2HC-type DUF2175 PF09943.7 141875.3_18524001_1 - 1.9 8.7 12.9 0.8 9.9 0.2 5.1 6 0 0 6 6 6 0 Uncharacterized protein conserved in archaea (DUF2175) HLH PF00010.24 143299.3_18522001_1 - 4.7e-15 55.1 0.1 9.5e-15 54.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CRM1_C PF08767.9 143299.3_18522001_1 - 0.02 14.0 0.3 0.041 12.9 0.3 1.4 1 0 0 1 1 1 0 CRM1 C terminal Hira PF07569.9 143299.3_18522001_1 - 0.077 12.6 4.6 0.31 10.6 4.6 2.1 1 1 0 1 1 1 0 TUP1-like enhancer of split F-box-like PF12937.5 143299.3_18522001_2 - 0.046 13.5 0.5 0.046 13.5 0.5 2.7 3 0 0 3 3 3 0 F-box-like FAD_binding_7 PF03441.12 169852.2_18524001_2 - 1.9e-57 193.8 0.2 2.8e-57 193.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.16 169852.2_18524001_2 - 1.9e-36 125.4 0.0 4e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Trypsin PF00089.24 141910.2_18522001_2 - 5.9e-48 163.4 0.3 6.9e-48 163.2 0.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 141910.2_18522001_2 - 1.1e-06 29.4 0.1 1.7e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.13 141910.2_18522001_2 - 0.039 13.4 0.0 0.77 9.1 0.0 2.0 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Filamin PF00630.17 001202309.1_18529001_1 - 8.8e-274 887.2 53.5 3.2e-19 69.5 0.0 20.2 20 0 0 20 20 20 20 Filamin/ABP280 repeat CH PF00307.29 001202309.1_18529001_1 - 2.4e-37 127.3 1.6 5.1e-23 81.2 0.4 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.11 001202309.1_18529001_1 - 4.9e-11 42.3 4.5 4.9 7.0 0.0 10.4 11 0 0 11 11 11 2 Y_Y_Y domain DUF5060 PF16586.3 001202309.1_18529001_1 - 1.3e-08 34.9 0.0 30 4.9 0.0 10.1 11 0 0 11 11 11 0 Domain of unknown function (DUF5060) YtkA PF13115.4 001202309.1_18529001_1 - 0.00014 22.2 7.7 23 5.6 0.2 9.8 11 1 1 12 12 12 0 YtkA-like CH_2 PF06294.9 001202309.1_18529001_1 - 0.00063 19.7 0.2 0.0049 16.8 0.1 2.4 3 0 0 3 3 3 1 CH-like domain in sperm protein PKD PF00801.18 001202309.1_18529001_1 - 0.0017 18.0 7.2 18 5.1 0.0 7.8 8 0 0 8 8 8 1 PKD domain CAMSAP_CH PF11971.6 001202309.1_18529001_1 - 0.0019 17.8 0.1 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 CAMSAP CH domain Big_3_5 PF16640.3 001202309.1_18529001_1 - 0.0041 17.1 28.2 2.2 8.4 0.0 10.7 13 0 0 13 13 13 1 Bacterial Ig-like domain (group 3) GDC-P PF02347.14 001275527.1_18527001_3 - 1.1e-194 647.1 0.0 5.9e-184 611.7 0.0 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.19 001275527.1_18527001_3 - 5.6e-06 25.7 0.1 1.2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.17 001275527.1_18527001_3 - 2.3e-05 23.4 0.0 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.18 001275527.1_18527001_3 - 0.0069 14.8 0.0 0.052 11.9 0.0 2.2 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme PI3_PI4_kinase PF00454.25 142645.3_18529001_1 - 1.8e-60 204.7 3.3 2.2e-60 204.4 1.4 2.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.18 142645.3_18529001_1 - 3.3e-48 163.4 1.1 5.9e-48 162.6 1.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.22 142645.3_18529001_1 - 1.1e-35 122.5 0.0 2.3e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.16 142645.3_18529001_1 - 1.6e-32 111.8 0.3 3.6e-32 110.6 0.3 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_p85B PF02192.14 142645.3_18529001_1 - 3.1e-21 74.7 0.0 6.6e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain DUF4135 PF13575.4 142645.3_18529001_1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PI3_PI4_kinase PF00454.25 001275841.1_18529001_3 - 5.8e-61 206.3 1.4 2.5e-60 204.3 1.4 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.18 001275841.1_18529001_3 - 3.7e-48 163.2 1.1 6.7e-48 162.4 1.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.22 001275841.1_18529001_3 - 1.2e-35 122.3 0.0 2.5e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.16 001275841.1_18529001_3 - 1.8e-32 111.5 0.3 4e-32 110.4 0.3 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_p85B PF02192.14 001275841.1_18529001_3 - 3.3e-21 74.7 0.0 7.4e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain DUF4135 PF13575.4 001275841.1_18529001_3 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) HSP70 PF00012.18 176503.2_18525001_3 - 4.4e-262 870.5 9.0 5e-262 870.3 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 176503.2_18525001_3 - 8.5e-18 64.1 0.2 2e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.14 176503.2_18525001_3 - 0.007 16.0 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.4 176503.2_18525001_3 - 0.016 15.5 1.0 5.3 7.4 0.0 3.1 3 1 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.16 176503.2_18525001_3 - 0.043 12.9 1.1 0.075 12.1 0.2 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Actin PF00022.17 176503.2_18525001_3 - 0.058 11.9 0.1 1.6 7.1 0.0 2.3 1 1 1 2 2 2 0 Actin PIG-L PF02585.15 206519.2_18524001_1 - 2.5e-26 92.7 0.0 3.9e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SNF2_N PF00176.21 170228.3_18529001_2 - 2.4e-55 187.5 0.1 5.3e-55 186.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.29 170228.3_18529001_2 - 9e-15 54.9 0.0 3.2e-14 53.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_S10 PF00450.20 142579.4_18524001_2 - 1.6e-91 307.7 0.8 2.5e-91 307.0 0.8 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.23 001104369.2_18529001_2 - 5.4e-42 143.8 0.0 7.5e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.10 001104369.2_18529001_2 - 8.4e-37 126.0 0.1 1.4e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.15 001104369.2_18529001_2 - 2e-26 92.7 0.0 2.9e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.4 001104369.2_18529001_2 - 2.5e-05 23.9 0.1 0.0064 16.0 0.0 2.9 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.19 001104369.2_18529001_2 - 0.0073 16.0 0.0 0.026 14.3 0.0 2.0 1 0 0 1 1 1 1 PQQ enzyme repeat APH PF01636.21 001104369.2_18529001_2 - 0.013 15.3 0.7 0.071 12.9 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.12 001104369.2_18529001_2 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.19 001276028.1_18528001_2 - 3e-16 59.1 0.0 7.2e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase BALF1 PF06861.9 001276028.1_18528001_2 - 0.047 13.2 0.1 0.096 12.2 0.1 1.4 1 0 0 1 1 1 0 BALF1 protein EF-hand_8 PF13833.4 169877.2_18525001_2 - 1.8e-17 62.7 4.2 5.9e-12 45.0 0.1 4.7 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_7 PF13499.4 169877.2_18525001_2 - 3.2e-15 56.2 8.4 2.5e-07 30.9 0.0 4.3 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.30 169877.2_18525001_2 - 4.7e-12 44.4 15.5 2e-06 26.8 0.5 5.6 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.4 169877.2_18525001_2 - 4.4e-11 41.7 9.2 4.8e-05 22.9 0.3 4.8 6 0 0 6 6 6 2 EF-hand domain EF-hand_5 PF13202.4 169877.2_18525001_2 - 1.9e-07 30.1 5.2 0.00056 19.2 0.2 4.2 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.5 169877.2_18525001_2 - 0.011 15.5 0.1 0.55 10.1 0.0 2.7 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand AMP-binding PF00501.26 141903.3_18524001_2 - 2.8e-64 217.1 0.0 3.5e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 141903.3_18524001_2 - 1.1e-14 55.0 0.6 1.9e-14 54.3 0.6 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tropomyosin PF00261.18 001275663.1_18523001_1 - 1.1e-84 283.4 77.4 6.9e-83 277.5 55.6 2.9 2 1 1 3 3 3 2 Tropomyosin Tropomyosin_1 PF12718.5 001275663.1_18523001_1 - 9.2e-33 113.2 66.4 2.1e-26 92.7 37.6 3.3 2 1 1 3 3 3 3 Tropomyosin like DUF745 PF05335.11 001275663.1_18523001_1 - 5e-05 23.0 47.5 0.0064 16.1 19.7 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF745) ERM PF00769.17 001275663.1_18523001_1 - 9.5e-05 22.2 64.9 0.0031 17.2 20.0 2.3 1 1 1 2 2 2 2 Ezrin/radixin/moesin family MscS_porin PF12795.5 001275663.1_18523001_1 - 0.00018 21.0 44.5 0.0014 18.1 21.9 2.5 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain ATG16 PF08614.9 001275663.1_18523001_1 - 0.00022 21.4 63.8 0.0065 16.5 14.7 3.2 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) Alanine_zipper PF11839.6 001275663.1_18523001_1 - 0.00058 20.0 43.4 0.091 12.9 6.1 4.3 2 1 2 4 4 4 2 Alanine-zipper, major outer membrane lipoprotein Cep57_CLD_2 PF14197.4 001275663.1_18523001_1 - 0.00067 19.6 3.1 0.00067 19.6 3.1 5.1 2 1 3 5 5 2 1 Centrosome localisation domain of PPC89 EzrA PF06160.10 001275663.1_18523001_1 - 0.0026 15.9 4.1 0.0026 15.9 4.1 3.5 1 1 2 3 3 3 2 Septation ring formation regulator, EzrA CLZ PF16526.3 001275663.1_18523001_1 - 0.0029 17.8 5.7 0.0029 17.8 5.7 5.8 1 1 5 6 6 6 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.10 001275663.1_18523001_1 - 0.0065 16.3 43.3 0.029 14.2 7.0 3.6 1 1 1 3 3 3 2 Laminin Domain II BST2 PF16716.3 001275663.1_18523001_1 - 0.0072 16.7 4.4 0.0072 16.7 4.4 5.4 1 1 6 7 7 5 2 Bone marrow stromal antigen 2 Reo_sigmaC PF04582.10 001275663.1_18523001_1 - 0.014 14.7 13.2 0.027 13.7 0.5 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein BCL_N PF04714.11 001275663.1_18523001_1 - 0.024 14.6 0.1 0.024 14.6 0.1 3.6 4 1 1 5 5 3 0 BCL7, N-terminal conserver region Spc7 PF08317.9 001275663.1_18523001_1 - 0.025 13.4 59.1 0.15 10.8 24.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.10 001275663.1_18523001_1 - 0.058 13.2 40.2 0.37 10.7 3.2 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) WEMBL PF05701.9 001275663.1_18523001_1 - 0.28 9.6 54.8 0.69 8.4 11.1 3.2 1 1 2 3 3 3 0 Weak chloroplast movement under blue light FPP PF05911.9 001275663.1_18523001_1 - 0.35 8.9 56.5 6.1 4.8 29.4 2.6 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil AAA_13 PF13166.4 001275663.1_18523001_1 - 0.45 9.0 46.1 0.048 12.2 27.5 2.3 1 1 1 2 2 2 0 AAA domain HOOK PF05622.10 001275663.1_18523001_1 - 0.49 8.4 61.2 0.78 7.7 15.5 3.1 1 1 2 3 3 3 0 HOOK protein IncA PF04156.12 001275663.1_18523001_1 - 0.5 10.0 55.5 5.4 6.6 24.7 3.3 1 1 1 2 2 2 0 IncA protein Uds1 PF15456.4 001275663.1_18523001_1 - 0.51 10.4 46.1 0.23 11.5 17.6 4.5 1 1 3 4 4 4 0 Up-regulated During Septation Fez1 PF06818.13 001275663.1_18523001_1 - 0.52 10.6 56.9 1.6 9.0 23.0 3.3 1 1 2 3 3 3 0 Fez1 Golgin_A5 PF09787.7 001275663.1_18523001_1 - 0.54 9.5 57.2 1.2 8.4 33.4 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 APG6 PF04111.10 001275663.1_18523001_1 - 0.59 9.3 60.2 0.019 14.2 22.9 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF724 PF05266.12 001275663.1_18523001_1 - 1.1 8.9 54.5 0.14 11.8 11.3 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.10 001275663.1_18523001_1 - 2.2 8.2 58.7 2.2 8.2 11.2 3.8 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.7 001275663.1_18523001_1 - 2.8 8.2 41.7 0.03 14.5 5.2 4.5 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.13 001275663.1_18523001_1 - 2.9 7.2 39.1 1.6e+04 -10.5 39.1 2.7 1 1 0 1 1 0 0 Exonuclease VII, large subunit DUF3584 PF12128.6 001275663.1_18523001_1 - 3.1 5.0 53.6 0.19 9.0 12.8 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) FUSC PF04632.10 001275663.1_18523001_1 - 5 5.4 15.7 0.35 9.2 0.8 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.7 001275663.1_18523001_1 - 5.6 6.9 65.0 1.1 9.2 19.3 3.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_I PF06008.12 001275663.1_18523001_1 - 5.7 6.4 48.7 0.09 12.3 5.1 3.5 1 1 0 2 2 2 0 Laminin Domain I DUF4472 PF14739.4 001275663.1_18523001_1 - 9.6 6.9 49.1 2.8 8.6 12.4 4.3 1 1 2 4 4 4 0 Domain of unknown function (DUF4472) SlyX PF04102.10 001275663.1_18523001_1 - 9.8 6.8 40.3 0.64 10.6 0.4 5.7 1 1 4 5 5 3 0 SlyX Aconitase PF00330.18 058023.5_18526001_1 - 1.4e-176 587.9 0.0 1.8e-176 587.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.17 058023.5_18526001_1 - 5.5e-46 156.0 0.0 4.7e-45 153.0 0.0 2.2 2 0 0 2 2 2 1 Aconitase C-terminal domain RRM_1 PF00076.20 001276031.1_18529001_1 - 2.9e-29 100.5 0.5 9.6e-14 50.8 0.2 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001276031.1_18529001_1 - 6.1e-09 35.8 0.7 0.00058 19.8 0.2 2.8 2 0 0 2 2 2 2 RNA recognition motif TFIIA PF03153.11 001276031.1_18529001_1 - 2.6 7.8 48.6 0.58 10.0 25.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DcpS_C PF11969.6 001260266.2_18526001_2 - 2.7e-07 30.9 0.1 4.4e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.21 001260266.2_18526001_2 - 0.0066 17.0 0.1 0.013 16.1 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.6 001260266.2_18526001_3 - 1e-34 119.3 7.8 1.3e-19 70.7 1.3 2.5 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.3 001260266.2_18526001_3 - 1.8e-32 111.5 5.4 6.5e-16 58.4 0.2 3.0 3 0 0 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.21 001260266.2_18526001_3 - 2.6e-10 40.8 2.4 0.00049 20.7 0.1 2.5 2 0 0 2 2 2 2 HIT domain zf-H2C2_5 PF13909.4 001260266.2_18526001_3 - 0.0091 15.6 0.6 1.3 8.7 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain ELFV_dehydrog_N PF02812.16 206551.3_18525001_1 - 1.1e-58 196.5 0.0 2.2e-58 195.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.19 206551.3_18525001_1 - 5.3e-52 176.8 0.0 1.1e-49 169.3 0.0 2.2 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IFT20 PF14931.4 206551.3_18525001_1 - 0.047 13.7 0.1 0.099 12.7 0.1 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Abhydrolase_1 PF00561.18 142795.4_18523001_2 - 4.6e-19 68.9 0.0 8.9e-12 45.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 142795.4_18523001_2 - 3.5e-14 53.8 0.9 4.7e-14 53.4 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 142795.4_18523001_2 - 2.6e-11 43.1 0.0 1.7e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.16 142795.4_18523001_2 - 0.00018 21.0 0.0 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.11 142795.4_18523001_2 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.19 142795.4_18523001_2 - 0.057 12.7 0.1 0.74 9.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family JmjC PF02373.20 001275903.2_18524001_2 - 1.9e-28 99.1 0.0 3.6e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.4 001275903.2_18524001_2 - 2.5e-18 66.7 0.0 8.2e-18 65.0 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain SR-25 PF10500.7 001275903.2_18524001_2 - 0.95 8.9 21.4 0.03 13.8 14.4 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.11 001275903.2_18524001_2 - 2.8 5.8 12.8 3.9 5.3 12.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CCDC106 PF15794.3 001275903.2_18524001_2 - 3.6 7.1 6.9 6.7 6.2 6.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 EF_assoc_2 PF08356.10 001275966.1_18528001_2 - 9.8e-33 111.9 0.0 2.4e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.20 001275966.1_18528001_2 - 3.6e-25 88.3 0.0 6.1e-15 55.1 0.0 2.5 2 1 0 2 2 2 2 Ras family EF_assoc_1 PF08355.10 001275966.1_18528001_2 - 5.4e-24 83.5 0.3 4.8e-23 80.5 0.4 2.2 2 0 0 2 2 2 1 EF hand associated Roc PF08477.11 001275966.1_18528001_2 - 1.2e-11 44.8 0.0 4e-05 23.7 0.0 3.5 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.30 001275966.1_18528001_2 - 1.8e-06 26.9 0.2 0.0022 17.3 0.0 2.6 2 0 0 2 2 2 2 EF hand DUF258 PF03193.14 001275966.1_18528001_2 - 7.8e-06 25.8 0.1 0.27 11.0 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function, DUF258 EF-hand_6 PF13405.4 001275966.1_18528001_2 - 0.00012 21.6 0.7 0.09 12.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.4 001275966.1_18528001_2 - 0.0007 18.9 0.1 0.003 16.9 0.0 2.1 2 0 0 2 2 2 1 EF hand AAA_22 PF13401.4 001275966.1_18528001_2 - 0.0015 18.6 0.0 0.58 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain EF-hand_7 PF13499.4 001275966.1_18528001_2 - 0.0018 18.6 0.0 0.8 10.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair AAA_16 PF13191.4 001275966.1_18528001_2 - 0.0018 18.5 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.4 001275966.1_18528001_2 - 0.0038 16.9 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.8 001275966.1_18528001_2 - 0.018 14.3 0.0 0.064 12.6 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA PF00004.27 001275966.1_18528001_2 - 0.021 15.1 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.25 001275966.1_18528001_2 - 0.028 14.8 0.0 0.41 11.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.15 001275966.1_18528001_2 - 0.032 13.9 2.0 11 5.5 0.4 3.9 3 1 0 4 4 4 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.7 001275966.1_18528001_2 - 0.036 13.7 0.1 5.1 6.7 0.0 3.0 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.12 001275966.1_18528001_2 - 0.051 13.4 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.10 001275966.1_18528001_2 - 0.057 13.2 0.0 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.21 001275966.1_18528001_2 - 0.078 12.9 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.19 001275966.1_18528001_2 - 0.083 12.2 0.0 0.87 8.9 0.0 2.5 3 0 0 3 3 3 0 ADP-ribosylation factor family RNA_helicase PF00910.20 001275966.1_18528001_2 - 0.093 13.0 0.0 8.9 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.15 001275966.1_18528001_2 - 0.11 12.4 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.4 001275966.1_18528001_2 - 0.14 11.7 0.4 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.17 001275966.1_18528001_2 - 0.2 11.1 0.4 39 3.7 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.20 001275969.1_18527001_3 - 2.1e-53 177.9 0.1 1.7e-21 75.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001275969.1_18527001_3 - 4.2e-08 32.7 0.0 0.093 12.2 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001275969.1_18527001_3 - 7.9e-06 25.6 0.5 0.003 17.3 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.3 001275969.1_18527001_3 - 0.00054 19.9 0.0 0.51 10.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.3 001275969.1_18527001_3 - 0.004 16.8 0.0 1.3 8.8 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF3089 PF11288.6 170273.2_18526001_3 - 0.04 13.3 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LRR_8 PF13855.4 001276066.2_18529001_1 - 5.9e-46 153.9 65.5 1.9e-13 49.8 5.1 8.8 3 1 8 11 11 11 11 Leucine rich repeat LRR_5 PF13306.4 001276066.2_18529001_1 - 1.1e-29 102.8 0.0 1.8e-08 34.2 0.0 3.5 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) TIR PF01582.18 001276066.2_18529001_1 - 1.2e-17 64.1 0.0 2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001276066.2_18529001_1 - 3.4e-14 52.5 72.1 0.0046 17.2 0.3 11.4 9 2 1 12 12 12 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001276066.2_18529001_1 - 4.1e-12 46.2 0.0 8.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.16 001276066.2_18529001_1 - 4.4e-10 38.8 3.6 2.2e-09 36.6 3.6 2.4 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRRCT PF01463.22 001276066.2_18529001_1 - 0.0026 18.0 0.2 0.008 16.5 0.2 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.4 001276066.2_18529001_1 - 0.014 14.8 23.0 0.28 10.5 2.1 5.2 3 1 1 5 5 5 0 Leucine-rich repeat DUF1863 PF08937.9 001276066.2_18529001_1 - 0.03 14.5 2.4 0.18 12.0 2.4 2.1 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) LRR_1 PF00560.31 001276066.2_18529001_1 - 0.1 13.0 51.7 1.1 9.9 0.1 12.8 14 1 1 15 15 15 0 Leucine Rich Repeat BRK PF07533.14 001276066.2_18529001_3 - 0.12 11.8 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 BRK domain Acyltransferase PF01553.19 170359.3_18526001_3 - 1.9e-19 69.5 0.0 8.3e-19 67.4 0.0 2.1 1 1 1 2 2 2 1 Acyltransferase COMPASS-Shg1 PF05205.10 001276101.1_18528001_2 - 4e-18 65.9 0.1 1.5e-17 64.0 0.1 2.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF2939 PF11159.6 001276101.1_18528001_2 - 0.44 10.8 1.3 38 4.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Peptidase_M1 PF01433.18 001104469.3_18529001_2 - 2.3e-109 366.1 0.0 3.3e-109 365.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.6 001104469.3_18529001_2 - 3.4e-61 207.4 0.3 6.5e-61 206.5 0.3 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.18 001260394.2_18529001_2 - 2.1e-109 366.2 0.0 2.9e-109 365.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.6 001260394.2_18529001_2 - 3e-61 207.6 0.3 6e-61 206.6 0.3 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain LIP1 PF15904.3 001276085.2_18529001_1 - 0.12 12.6 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 Tub PF01167.16 001276085.2_18529001_2 - 1.5e-31 109.7 0.0 9.4e-26 90.7 0.1 2.7 3 0 0 3 3 3 2 Tub family ANAPC4_WD40 PF12894.5 001276085.2_18529001_2 - 6e-07 29.6 0.8 0.0042 17.2 0.1 4.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SOCS_box PF07525.14 001276085.2_18529001_2 - 0.0013 18.9 2.5 0.0029 17.8 2.5 1.6 1 0 0 1 1 1 1 SOCS box IKI3 PF04762.10 001276085.2_18529001_2 - 0.025 12.4 0.1 0.047 11.6 0.1 1.3 1 0 0 1 1 1 0 IKI3 family DUF3527 PF12043.6 001276085.2_18529001_2 - 0.033 13.6 0.1 0.033 13.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3527) WD40 PF00400.30 001276085.2_18529001_2 - 0.92 10.4 3.5 50 4.9 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat PsbL PF02419.15 001275860.1_18525001_1 - 0.095 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 PsbL protein 40S_SA_C PF16122.3 001275860.1_18525001_3 - 0.06 14.6 0.2 0.13 13.5 0.2 1.5 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus E1-E2_ATPase PF00122.18 206526.3_18529001_1 - 3.7e-56 189.8 1.7 7.3e-56 188.8 1.7 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.19 206526.3_18529001_1 - 2e-44 151.4 0.3 2e-44 151.4 0.3 2.6 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.4 206526.3_18529001_1 - 1.7e-24 85.6 0.0 3.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.24 206526.3_18529001_1 - 1.4e-19 71.1 0.0 3.3e-11 43.7 0.0 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 206526.3_18529001_1 - 2.7e-19 68.5 0.0 5.2e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.10 206526.3_18529001_1 - 2.9e-05 23.8 4.9 0.002 17.8 1.0 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_efflux PF01545.19 206526.3_18529001_1 - 0.0089 15.6 0.1 0.021 14.4 0.1 1.5 1 1 0 1 1 1 1 Cation efflux family HAD PF12710.5 206526.3_18529001_1 - 0.055 13.7 0.0 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SfLAP PF11139.6 206526.3_18529001_1 - 0.18 11.1 2.6 0.43 9.9 0.0 2.3 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein Tetraspannin PF00335.18 206526.3_18529001_1 - 2.1 8.0 5.7 0.58 9.8 0.6 2.3 2 0 0 2 2 2 0 Tetraspanin family Calx-beta PF03160.12 001260283.2_18528001_2 - 7.9e-55 183.1 4.1 3.8e-28 97.5 0.2 2.6 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.22 001260283.2_18528001_2 - 4.8e-53 179.1 45.2 3.6e-29 101.5 14.7 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.3 001260283.2_18528001_2 - 6.3e-38 130.0 4.1 1.2e-37 129.1 4.1 1.5 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain HTH_WhiA PF02650.12 001260283.2_18528001_2 - 0.088 13.0 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 WhiA C-terminal HTH domain Myosin_head PF00063.19 001300572.1_18529001_2 - 3.3e-261 868.2 0.1 3.3e-261 868.2 0.1 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin-VI_CBD PF16521.3 001300572.1_18529001_2 - 1.6e-42 143.4 0.1 1.6e-41 140.1 0.1 2.5 2 0 0 2 2 2 1 Myosin VI cargo binding domain Myosin_N PF02736.17 001300572.1_18529001_2 - 1.7e-07 30.8 0.1 1.7e-06 27.6 0.1 2.2 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain IQ PF00612.25 001300572.1_18529001_2 - 0.017 14.8 1.3 0.054 13.2 1.3 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF4496 PF14908.4 001300572.1_18529001_2 - 0.081 12.8 0.1 0.41 10.6 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) AAA_22 PF13401.4 001300572.1_18529001_2 - 0.12 12.6 2.7 0.21 11.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.4 001300572.1_18529001_2 - 0.58 10.4 0.0 0.58 10.4 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain DDHD PF02862.15 001300572.1_18529001_2 - 4.1 7.3 9.6 7.8 6.4 9.6 1.5 1 0 0 1 1 1 0 DDHD domain SLC3A2_N PF16028.3 001260289.1_18522001_3 - 5.1e-18 64.3 0.0 7.8e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Annexin PF00191.18 001275868.1_18523001_2 - 2.7e-100 328.3 9.1 1.4e-24 85.7 0.1 4.2 4 0 0 4 4 4 4 Annexin Annexin PF00191.18 001275867.1_18523001_1 - 2.7e-100 328.3 9.1 1.4e-24 85.7 0.1 4.2 4 0 0 4 4 4 4 Annexin Ras PF00071.20 134310.3_18524001_1 - 8.1e-62 207.5 0.1 1.1e-61 207.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 134310.3_18524001_1 - 1.8e-34 118.4 0.1 2.7e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 134310.3_18524001_1 - 2.5e-11 43.2 0.0 3.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 134310.3_18524001_1 - 2e-06 27.7 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.4 134310.3_18524001_1 - 0.00043 20.4 0.0 0.0024 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.14 134310.3_18524001_1 - 0.00075 19.3 0.1 0.066 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 134310.3_18524001_1 - 0.0015 18.0 0.0 0.0033 16.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.16 134310.3_18524001_1 - 0.046 13.1 0.1 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.7 134310.3_18524001_1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.10 134310.3_18524001_1 - 0.094 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.4 134310.3_18524001_1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.25 134310.3_18524001_1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RCDG1 PF15725.3 134310.3_18524001_1 - 2.2 8.7 6.3 4.9 7.5 6.3 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Ras PF00071.20 057822.4_18524001_2 - 6.6e-62 207.7 0.1 8.8e-62 207.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 057822.4_18524001_2 - 1.5e-34 118.7 0.1 2.3e-34 118.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 057822.4_18524001_2 - 2e-11 43.5 0.0 3.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 057822.4_18524001_2 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.4 057822.4_18524001_2 - 0.00033 20.8 0.0 0.002 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.14 057822.4_18524001_2 - 0.00056 19.7 0.1 0.058 13.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 057822.4_18524001_2 - 0.0012 18.3 0.0 0.003 17.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.16 057822.4_18524001_2 - 0.036 13.4 0.1 0.1 12.0 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.10 057822.4_18524001_2 - 0.078 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.7 057822.4_18524001_2 - 0.078 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.4 057822.4_18524001_2 - 0.084 13.1 0.1 0.13 12.4 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.25 057822.4_18524001_2 - 0.096 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RCDG1 PF15725.3 057822.4_18524001_2 - 2.4 8.5 6.3 4.3 7.7 6.3 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein ABC_tran PF00005.25 001260357.1_18529001_1 - 1.1e-51 174.8 0.0 2.3e-29 102.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.21 001260357.1_18529001_1 - 5.6e-46 157.3 34.4 1e-27 97.3 17.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.17 001260357.1_18529001_1 - 2.3e-10 40.1 0.6 0.032 13.5 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.4 001260357.1_18529001_1 - 2.2e-09 37.4 0.3 0.039 13.6 0.0 4.0 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.4 001260357.1_18529001_1 - 6.4e-06 26.5 0.5 0.075 13.3 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.21 001260357.1_18529001_1 - 1.1e-05 25.3 0.2 0.013 15.4 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.14 001260357.1_18529001_1 - 4.5e-05 23.3 0.3 0.074 12.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.4 001260357.1_18529001_1 - 7.4e-05 22.3 0.4 0.26 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.4 001260357.1_18529001_1 - 0.00045 20.4 0.1 0.64 10.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.21 001260357.1_18529001_1 - 0.002 18.1 0.6 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 Dynamin family AAA_23 PF13476.4 001260357.1_18529001_1 - 0.0049 17.3 1.8 1.8 8.9 0.2 3.0 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.15 001260357.1_18529001_1 - 0.013 15.4 1.3 0.92 9.4 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_30 PF13604.4 001260357.1_18529001_1 - 0.02 14.5 0.1 4.2 6.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.4 001260357.1_18529001_1 - 0.089 13.2 0.0 18 5.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain UAA PF08449.9 142692.3_18524001_2 - 1e-48 166.0 15.5 1.3e-48 165.7 15.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.18 142692.3_18524001_2 - 5.3e-10 39.5 24.4 3.4e-06 27.1 11.3 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.14 142692.3_18524001_2 - 9.9e-08 31.5 12.6 4.9e-07 29.2 12.6 1.9 1 1 0 1 1 1 1 Triose-phosphate Transporter family UQ_con PF00179.24 001275740.1_18524001_3 - 1.3e-17 63.6 0.0 2.1e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AMMECR1 PF01871.15 001170234.2_18524001_1 - 4.6e-49 166.1 0.0 9.3e-49 165.1 0.0 1.4 2 0 0 2 2 2 1 AMMECR1 DUF2205 PF10224.7 143295.4_18522001_1 - 8.5e-29 99.2 4.0 1.3e-28 98.7 4.0 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) CASP_C PF08172.10 143295.4_18522001_1 - 0.012 14.9 1.0 0.014 14.6 1.0 1.1 1 0 0 1 1 1 0 CASP C terminal CENP-H PF05837.10 143295.4_18522001_1 - 0.012 15.9 1.7 0.018 15.3 1.7 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.11 143295.4_18522001_1 - 0.014 15.9 1.0 0.022 15.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.19 143295.4_18522001_1 - 0.015 15.3 0.8 0.024 14.6 0.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 143295.4_18522001_1 - 0.016 14.9 3.6 0.022 14.4 3.6 1.1 1 0 0 1 1 1 0 IncA protein FlaC_arch PF05377.9 143295.4_18522001_1 - 0.018 15.3 1.8 0.037 14.3 1.8 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.4 143295.4_18522001_1 - 0.019 14.7 3.4 0.026 14.3 3.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FliT PF05400.11 143295.4_18522001_1 - 0.023 15.3 2.1 0.037 14.7 2.1 1.3 1 0 0 1 1 1 0 Flagellar protein FliT CENP-F_leu_zip PF10473.7 143295.4_18522001_1 - 0.026 14.4 3.7 0.036 13.9 3.7 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MbeD_MobD PF04899.10 143295.4_18522001_1 - 0.04 13.9 1.2 0.063 13.3 1.2 1.4 1 0 0 1 1 1 0 MbeD/MobD like ZapB PF06005.10 143295.4_18522001_1 - 0.057 13.7 3.0 0.092 13.1 3.0 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Sas10_Utp3 PF04000.13 143295.4_18522001_1 - 0.07 13.6 0.3 0.14 12.7 0.3 1.4 1 0 0 1 1 1 0 Sas10/Utp3/C1D family DASH_Dad4 PF08650.8 143295.4_18522001_1 - 0.11 12.3 0.7 0.19 11.6 0.7 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad4 HALZ PF02183.16 143295.4_18522001_1 - 0.19 11.8 7.7 0.48 10.5 2.6 2.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper SMC_N PF02463.17 142954.4_18528001_1 - 4.1e-52 176.7 42.6 4.3e-51 173.3 42.6 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.11 142954.4_18528001_1 - 4e-22 78.6 0.5 2.3e-21 76.2 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.4 142954.4_18528001_1 - 3e-12 46.7 13.6 3e-12 46.7 13.6 4.1 2 2 2 4 4 2 1 AAA ATPase domain AAA_21 PF13304.4 142954.4_18528001_1 - 4e-12 46.4 6.7 6.1e-07 29.4 0.1 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.4 142954.4_18528001_1 - 1e-06 28.2 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.4 142954.4_18528001_1 - 3.9e-05 24.1 36.7 3.9e-05 24.1 36.7 7.2 2 2 3 5 5 1 1 AAA domain Baculo_PEP_C PF04513.10 142954.4_18528001_1 - 0.0053 16.7 15.9 0.13 12.1 0.1 6.0 5 1 1 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.10 142954.4_18528001_1 - 0.06 12.6 12.7 1.4 8.2 0.3 4.2 3 1 0 4 4 4 0 Reovirus sigma C capsid protein ABC_tran PF00005.25 142954.4_18528001_1 - 0.42 11.0 0.0 0.42 11.0 0.0 6.7 4 3 0 4 4 2 0 ABC transporter CoA_transf_3 PF02515.15 142954.4_18528001_1 - 0.44 9.5 3.5 1.7 7.5 3.5 1.9 1 0 0 1 1 1 0 CoA-transferase family III DUF1664 PF07889.10 142954.4_18528001_1 - 2.1 8.2 72.7 0.22 11.4 7.0 8.8 5 3 2 8 8 8 0 Protein of unknown function (DUF1664) Exo84_C PF16528.3 143197.2_18525001_2 - 2e-18 66.8 5.4 2e-18 66.8 5.4 2.4 2 1 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.9 143197.2_18525001_2 - 5.7e-16 58.3 1.7 5.7e-16 58.3 1.7 2.3 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.9 143197.2_18525001_2 - 0.00022 21.2 2.2 0.0012 18.8 0.6 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 PH PF00169.27 143197.2_18525001_2 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 PH domain CCDC84 PF14968.4 143197.2_18525001_2 - 6.8 6.1 10.5 0.57 9.6 2.6 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 FXMRP1_C_core PF12235.6 001275518.1_18525001_2 - 6.6e-24 85.0 17.7 6.6e-24 85.0 17.7 3.3 2 1 1 3 3 3 1 Fragile X-related 1 protein core C terminal KH_1 PF00013.27 001275518.1_18525001_2 - 4.4e-19 67.9 0.3 1.2e-09 37.8 0.1 2.7 2 0 0 2 2 2 2 KH domain Agenet PF05641.10 001275518.1_18525001_2 - 5.9e-05 23.3 0.3 0.21 12.0 0.2 3.2 3 0 0 3 3 3 2 Agenet domain KH_4 PF13083.4 001275518.1_18525001_2 - 0.00014 21.5 1.0 0.9 9.3 0.0 3.1 3 0 0 3 3 3 2 KH domain S1 PF00575.21 001275518.1_18525001_2 - 0.064 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 S1 RNA binding domain KH_5 PF13184.4 001275518.1_18525001_2 - 0.083 12.9 0.7 1 9.4 0.3 2.3 2 0 0 2 2 2 0 NusA-like KH domain KH_2 PF07650.15 001275518.1_18525001_2 - 0.12 12.1 1.2 7.8 6.3 0.0 2.7 2 0 0 2 2 2 0 KH domain Creatinase_N_2 PF16189.3 001104289.2_18526001_3 - 1e-40 139.3 0.0 1.8e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.22 001104289.2_18526001_3 - 6e-30 104.4 0.0 1.1e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.3 001104289.2_18526001_3 - 8.9e-16 57.6 0.0 1.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.16 001104289.2_18526001_3 - 3e-14 53.7 0.0 7.7e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain ELO PF01151.16 001259978.1_18525001_2 - 3.6e-66 223.1 28.2 3.6e-66 223.1 28.2 1.7 2 0 0 2 2 2 1 GNS1/SUR4 family Sugar_tr PF00083.22 169865.2_18526001_1 - 7.4e-24 84.3 15.3 1.3e-23 83.5 15.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 169865.2_18526001_1 - 2.9e-21 75.6 45.3 5.9e-20 71.3 22.7 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily PH PF00169.27 001260007.1_18529001_1 - 4.6e-07 30.2 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 PH domain DAGK_acc PF00609.17 001260040.2_18529001_1 - 1.6e-53 181.2 0.0 2.8e-53 180.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.22 001260040.2_18529001_1 - 3e-25 88.1 0.0 6.1e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SAM_1 PF00536.28 001260040.2_18529001_1 - 3e-17 62.7 0.1 6e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) C1_1 PF00130.20 001260040.2_18529001_1 - 4.9e-17 61.4 31.0 1.6e-09 37.4 5.4 3.3 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.15 001260040.2_18529001_1 - 3.2e-15 55.9 0.0 2.4e-14 53.1 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.27 001260040.2_18529001_1 - 1.4e-12 47.9 0.6 4.4e-12 46.3 0.6 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 001260040.2_18529001_1 - 0.036 14.4 1.6 1 9.7 1.6 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain SAM_PNT PF02198.14 001260040.2_18529001_1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.8 001260040.2_18529001_1 - 0.059 13.5 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif C1_2 PF03107.14 001260040.2_18529001_1 - 2.9 8.2 21.0 0.8 9.9 7.2 3.4 3 0 0 3 3 3 0 C1 domain Xan_ur_permease PF00860.18 001275530.1_18526001_3 - 9.6e-80 268.0 27.6 1.3e-79 267.5 27.6 1.2 1 0 0 1 1 1 1 Permease family Bap31 PF05529.10 001275530.1_18526001_3 - 0.8 9.1 4.3 0.21 11.1 0.1 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF1049 PF06305.9 001275530.1_18526001_3 - 5.8 6.7 6.9 20 5.0 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) LIM PF00412.20 001260058.2_18523001_3 - 3.1e-55 184.1 62.0 1e-14 54.3 3.7 5.5 5 0 0 5 5 5 5 LIM domain zf-RRN7 PF11781.6 001260058.2_18523001_3 - 0.039 13.5 0.7 0.039 13.5 0.7 7.7 9 0 0 9 9 9 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4428 PF14471.4 001260058.2_18523001_3 - 0.063 13.1 0.2 0.063 13.1 0.2 5.6 6 1 1 7 7 7 0 Domain of unknown function (DUF4428) dNK PF01712.17 001275892.1_18523001_1 - 1.6e-34 119.4 0.2 2.3e-34 118.9 0.2 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.4 001275892.1_18523001_1 - 0.00025 21.1 0.0 0.00095 19.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain SKI PF01202.20 001275892.1_18523001_1 - 0.0013 18.7 0.1 2.6 8.0 0.0 3.1 2 1 0 2 2 2 2 Shikimate kinase Thymidylate_kin PF02223.15 001275892.1_18523001_1 - 0.0029 17.2 0.0 0.029 13.9 0.1 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.4 001275892.1_18523001_1 - 0.0036 17.7 0.0 0.008 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain TsaE PF02367.15 001275892.1_18523001_1 - 0.006 16.5 0.0 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.16 001275892.1_18523001_1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_PrkA PF08298.9 001275892.1_18523001_1 - 0.038 12.8 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_22 PF13401.4 001275892.1_18523001_1 - 0.1 12.8 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.10 001275892.1_18523001_1 - 0.12 11.6 0.0 0.35 10.0 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin Homeobox PF00046.27 079797.3_18523001_1 - 4.9e-20 71.0 8.6 9.8e-20 70.0 8.6 1.5 1 0 0 1 1 1 1 Homeobox domain SUIM_assoc PF16619.3 079797.3_18523001_1 - 0.0013 18.6 4.6 0.017 15.1 1.5 3.0 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF3983 PF13137.4 079797.3_18523001_1 - 0.014 15.1 1.9 0.024 14.3 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Homeobox_KN PF05920.9 079797.3_18523001_1 - 0.036 13.8 1.2 0.15 11.8 1.2 2.2 1 0 0 1 1 1 0 Homeobox KN domain Med3 PF11593.6 079797.3_18523001_1 - 0.09 11.8 4.1 0.18 10.8 4.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.20 001014674.2_18526001_2 - 2.3e-32 110.5 0.2 7.8e-15 54.3 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001014674.2_18526001_2 - 6.9e-06 26.0 0.3 0.054 13.5 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.4 001014674.2_18526001_2 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DNA_pol_A_exo1 PF01612.18 001260119.2_18524001_2 - 1.6e-17 63.7 0.0 2.7e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Ribosomal_S14 PF00253.19 001260119.2_18524001_2 - 0.13 11.9 2.0 0.14 11.8 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e zf-C2H2 PF00096.24 001260136.2_18529001_3 - 2.4e-12 46.5 26.5 0.0055 17.0 1.1 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001260136.2_18529001_3 - 9e-08 32.2 22.5 0.15 12.8 0.6 5.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001260136.2_18529001_3 - 3.2e-06 27.2 34.0 0.0045 17.3 0.3 6.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_6 PF13912.4 001260136.2_18529001_3 - 0.19 11.6 21.7 1.2 9.0 2.6 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Abi_HHR PF07815.12 001260161.1_18525001_1 - 1.8e-33 114.4 1.0 4.9e-33 113.0 1.0 1.8 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.4 001260161.1_18525001_1 - 3e-16 58.9 1.5 1.3e-15 56.8 0.7 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.26 001260161.1_18525001_1 - 4.8e-14 51.6 0.5 9.6e-14 50.6 0.5 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001260161.1_18525001_1 - 1.9e-10 40.2 0.1 5.1e-10 38.7 0.0 1.8 1 1 1 2 2 2 1 Variant SH3 domain GD_N PF16030.3 001260165.2_18522001_1 - 1.3e-19 70.4 0.1 1.7e-19 70.0 0.1 1.1 1 0 0 1 1 1 1 Serine protease gd N-terminus LysM PF01476.18 001260168.1_18525001_1 - 7.2e-06 25.9 0.0 1.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 LysM domain WD40 PF00400.30 001300616.1_18529001_1 - 2.8e-08 34.2 8.6 0.0084 16.8 0.5 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001300616.1_18529001_1 - 2.8e-07 30.6 0.0 0.66 10.2 0.0 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_C PF00137.19 001260182.2_18523001_1 - 4.7e-24 84.4 37.9 6.8e-14 51.8 7.6 2.8 3 0 0 3 3 3 2 ATP synthase subunit C UPF0167 PF03691.12 001260182.2_18523001_2 - 0.041 13.5 0.9 0.076 12.6 0.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Iso_dh PF00180.18 142743.3_18524001_2 - 1.1e-68 231.8 0.1 1.4e-68 231.5 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase T2SS-T3SS_pil_N PF13629.4 080511.3_18522001_2 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Pilus formation protein N terminal region ELH PF02323.13 080511.3_18522001_3 - 0.011 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Egg-laying hormone precursor ELH PF02323.13 001275982.1_18522001_1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Egg-laying hormone precursor Sec20 PF03908.11 001275982.1_18522001_1 - 0.068 13.0 0.1 17 5.3 0.0 2.3 2 0 0 2 2 2 0 Sec20 T2SS-T3SS_pil_N PF13629.4 001275982.1_18522001_3 - 0.071 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Pilus formation protein N terminal region Pigment_DH PF06324.9 079793.3_18522001_1 - 2.7e-09 36.3 3.7 6.4e-09 35.1 3.7 1.7 1 0 0 1 1 1 1 Pigment-dispersing hormone (PDH) CUB PF00431.18 001260257.2_18529001_3 - 1e-76 254.2 0.4 1.5e-20 73.4 0.0 5.3 5 0 0 5 5 5 5 CUB domain Ldl_recept_a PF00057.16 001260257.2_18529001_3 - 6.4e-06 26.2 6.1 1.8e-05 24.7 6.1 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A SCP2 PF02036.15 001260259.2_18521001_1 - 1.5e-08 34.9 0.2 2e-08 34.5 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.4 001260259.2_18521001_1 - 1.7e-05 24.9 0.1 2.5e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal GDNF PF02351.14 001260281.2_18529001_2 - 2.4e-22 79.6 72.3 7e-10 39.6 7.3 5.4 5 0 0 5 5 5 4 GDNF/GAS1 domain Mucin PF01456.15 001260281.2_18529001_2 - 0.072 12.9 33.6 0.81 9.5 0.2 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein FAP PF07174.9 001260281.2_18529001_2 - 0.76 9.0 8.4 1.8 7.8 8.4 1.6 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) T2SSC PF11356.6 001260281.2_18529001_3 - 0.36 10.6 2.6 0.81 9.5 2.6 1.5 1 0 0 1 1 1 0 Type II secretion system protein C CEP19 PF14933.4 001260321.2_18522001_1 - 0.016 15.4 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 CEP19-like protein Folate_carrier PF01770.16 141772.3_18524001_1 - 5.2e-163 542.4 15.1 6.3e-163 542.2 15.1 1.1 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.14 141772.3_18524001_1 - 2.7e-11 42.9 16.1 2.7e-11 42.9 16.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Bacteriocin_IIc PF10439.7 141772.3_18524001_1 - 0.062 13.3 0.2 0.19 11.7 0.2 1.8 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PEX11 PF05648.12 001260334.1_18522001_1 - 8.8e-47 159.3 0.1 1.1e-46 159.0 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DAGK_acc PF00609.17 001260346.1_18529001_2 - 1.2e-53 181.5 0.0 2.2e-53 180.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain RA PF00788.21 001260346.1_18529001_2 - 1.8e-32 111.7 0.0 2.3e-18 66.4 0.0 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.20 001260346.1_18529001_2 - 4.7e-29 99.9 46.2 2.3e-12 46.4 6.5 3.4 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.22 001260346.1_18529001_2 - 9.1e-21 73.6 0.0 2.2e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_2 PF03107.14 001260346.1_18529001_2 - 0.00059 20.0 32.7 0.0067 16.6 3.5 3.8 3 0 0 3 3 3 2 C1 domain TUG-UBL1 PF11470.6 001260346.1_18529001_2 - 0.014 15.5 0.0 0.37 10.9 0.0 2.6 2 0 0 2 2 2 0 TUG ubiquitin-like domain Mito_carr PF00153.25 141777.4_18525001_3 - 1.5e-65 217.1 2.0 1.7e-23 82.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ig_3 PF13927.4 001260406.2_18529001_3 - 3.1e-36 123.7 9.2 3.7e-09 36.9 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.4 001260406.2_18529001_3 - 4.2e-29 100.6 5.4 5.8e-12 45.7 0.0 6.6 6 1 0 6 6 6 4 Immunoglobulin domain C2-set_2 PF08205.10 001260406.2_18529001_3 - 4.7e-28 97.0 0.6 1.2e-12 47.6 0.0 4.1 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain ig PF00047.23 001260406.2_18529001_3 - 7.9e-28 96.3 1.4 6.6e-05 22.9 0.1 6.4 5 2 0 5 5 5 4 Immunoglobulin domain I-set PF07679.14 001260406.2_18529001_3 - 4.1e-23 81.1 0.7 1.2e-05 25.1 0.0 6.0 6 0 0 6 6 6 4 Immunoglobulin I-set domain V-set PF07686.15 001260406.2_18529001_3 - 5.4e-15 55.4 0.2 7.1e-09 35.7 0.0 5.4 4 1 1 5 5 5 2 Immunoglobulin V-set domain fn3 PF00041.19 001260406.2_18529001_3 - 3.2e-05 24.0 0.2 0.00023 21.3 0.0 2.5 3 0 0 3 3 3 1 Fibronectin type III domain Izumo-Ig PF16706.3 001260406.2_18529001_3 - 0.0019 18.1 0.0 0.061 13.2 0.0 2.5 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain GBP PF02263.17 170157.2_18527001_2 - 2.3e-100 335.1 0.0 3.2e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.12 170157.2_18527001_2 - 0.0016 17.8 0.6 0.0041 16.4 0.6 1.6 2 0 0 2 2 2 1 Guanylate-binding protein, C-terminal domain DUF2207 PF09972.7 170157.2_18527001_2 - 0.059 12.0 0.1 0.088 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_M1 PF01433.18 001260426.2_18526001_1 - 4.4e-129 431.0 0.3 5.3e-129 430.8 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.6 001260426.2_18526001_2 - 7.1e-70 235.9 1.2 8.9e-70 235.6 1.2 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Diedel PF13164.4 001260428.1_18521001_1 - 9.6e-22 77.1 14.3 1.4e-21 76.6 14.3 1.2 1 0 0 1 1 1 1 Diedel Gb3_synth PF04572.10 001260428.1_18521001_2 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region Sex_peptide PF08138.9 001260430.1_18521001_1 - 3e-05 23.9 1.3 3.9e-05 23.6 1.3 1.2 1 0 0 1 1 1 1 Sex peptide (SP) family zf-H2C2_2 PF13465.4 141794.2_18524001_2 - 3.2e-23 80.9 41.7 4.5e-05 23.6 0.3 9.4 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2 PF00096.24 141794.2_18524001_2 - 3.9e-19 67.8 53.3 0.0002 21.5 1.3 8.0 8 0 0 8 8 7 7 Zinc finger, C2H2 type THAP PF05485.10 141794.2_18524001_2 - 2.9e-14 53.7 2.9 2.9e-14 53.7 2.9 3.7 2 1 1 3 3 1 1 THAP domain zf-C2H2_4 PF13894.4 141794.2_18524001_2 - 2.6e-11 43.2 59.8 0.0022 18.5 1.4 8.7 10 0 0 10 10 7 7 C2H2-type zinc finger zf-AD PF07776.13 141794.2_18524001_2 - 7.7e-09 35.5 0.3 7.7e-09 35.5 0.3 4.1 4 1 1 5 5 4 1 Zinc-finger associated domain (zf-AD) zf-met PF12874.5 141794.2_18524001_2 - 2e-06 27.9 34.4 4e-05 23.7 3.3 6.8 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 141794.2_18524001_2 - 0.0014 18.4 2.1 0.0014 18.4 2.1 7.4 8 0 0 8 8 8 3 C2H2-type zinc finger zf-DBF PF07535.10 141794.2_18524001_2 - 0.023 14.7 0.7 0.023 14.7 0.7 3.0 3 0 0 3 3 3 0 DBF zinc finger Ribosomal_L32p PF01783.21 141794.2_18524001_2 - 0.023 14.8 0.6 0.023 14.8 0.6 3.5 3 1 0 3 3 3 0 Ribosomal L32p protein family HypA PF01155.17 141794.2_18524001_2 - 0.082 12.8 17.1 1.4 8.8 0.4 4.7 3 1 1 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_11 PF16622.3 141794.2_18524001_2 - 0.098 12.3 20.3 0.56 9.9 0.2 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.3 141794.2_18524001_2 - 0.13 12.9 29.5 0.22 12.2 0.3 5.4 4 2 2 6 6 5 0 zinc-ribbon family AP3D1 PF06375.9 141794.2_18524001_2 - 0.26 11.4 7.0 0.099 12.8 3.1 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF1677 PF07911.11 141794.2_18524001_2 - 0.87 9.9 4.9 0.57 10.5 0.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1677) zf-C2H2_jaz PF12171.6 141794.2_18524001_2 - 4.5 7.6 43.2 0.23 11.7 2.3 6.4 8 0 0 8 8 7 0 Zinc-finger double-stranded RNA-binding RRM_5 PF13893.4 001260469.2_18528001_3 - 6.1e-45 151.7 3.2 1.8e-31 108.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 001260469.2_18528001_3 - 1e-25 89.2 0.0 1.7e-07 30.8 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfatase PF00884.21 001275697.1_18529001_3 - 3.8e-55 187.3 1.0 5.4e-55 186.8 1.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF3740 PF12548.6 001275697.1_18529001_3 - 1.3e-31 109.9 2.6 1.3e-31 109.9 2.6 2.5 2 0 0 2 2 2 1 Sulfatase protein Phosphodiest PF01663.20 001275697.1_18529001_3 - 0.00019 21.0 1.7 0.00093 18.7 0.5 2.5 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase PAPS_reduct PF01507.17 001275697.1_18529001_3 - 0.045 13.6 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Sulfatase PF00884.21 001275698.1_18529001_1 - 3e-55 187.7 1.0 4.4e-55 187.1 1.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF3740 PF12548.6 001275698.1_18529001_1 - 1.4e-31 109.8 2.9 1.4e-31 109.8 2.9 2.6 2 0 0 2 2 2 1 Sulfatase protein Phosphodiest PF01663.20 001275698.1_18529001_1 - 0.00012 21.7 1.5 0.00073 19.1 0.5 2.6 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase PAPS_reduct PF01507.17 001275698.1_18529001_1 - 0.04 13.8 0.2 0.091 12.7 0.2 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family zf-C2H2 PF00096.24 001300361.1_18523001_2 - 1.2e-17 63.1 45.3 0.00035 20.7 0.2 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-AD PF07776.13 001300361.1_18523001_2 - 4.4e-12 45.9 1.6 4.4e-12 45.9 1.6 3.0 3 0 0 3 3 3 1 Zinc-finger associated domain (zf-AD) zf-C2H2_jaz PF12171.6 001300361.1_18523001_2 - 3.7e-10 39.7 25.6 0.00097 19.3 5.7 6.3 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.4 001300361.1_18523001_2 - 1.8e-09 37.4 45.0 3.2e-06 27.2 0.3 6.7 8 0 0 8 8 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 001300361.1_18523001_2 - 1.8e-08 34.3 41.8 0.075 13.8 2.3 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.5 001300361.1_18523001_2 - 0.00015 21.9 36.6 0.0013 18.9 5.4 6.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001300361.1_18523001_2 - 0.0043 16.8 1.6 0.0043 16.8 1.6 6.5 7 0 0 7 7 7 2 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001300361.1_18523001_2 - 0.011 15.9 3.4 0.011 15.9 3.4 3.5 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.5 001300361.1_18523001_2 - 0.026 14.7 1.1 0.026 14.7 1.1 4.5 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) TF_Zn_Ribbon PF08271.10 001300361.1_18523001_2 - 0.14 11.6 3.9 0.17 11.3 0.0 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding DZR PF12773.5 001300361.1_18523001_2 - 7 6.6 20.0 1.9 8.4 2.7 4.5 4 2 0 4 4 4 0 Double zinc ribbon zinc_ribbon_15 PF17032.3 001300361.1_18523001_2 - 8.2 7.1 18.2 41 4.9 0.0 4.2 4 1 1 5 5 5 0 zinc-ribbon family Glycogen_syn PF05693.11 142165.3_18527001_1 - 0 1193.3 0.0 0 1193.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.9 142165.3_18527001_1 - 1.4e-05 24.8 0.4 6.9e-05 22.5 0.1 2.2 3 0 0 3 3 3 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 142165.3_18527001_1 - 4.2e-05 23.1 0.0 0.0009 18.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 142165.3_18527001_1 - 0.00019 21.7 0.0 0.011 16.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 LRR_8 PF13855.4 001144565.2_18527001_2 - 5.6e-16 57.9 16.7 1.4e-07 31.1 4.2 4.6 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.5 001144565.2_18527001_2 - 7.9e-10 38.7 16.5 0.0018 18.4 2.2 4.8 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001144565.2_18527001_2 - 0.0023 17.3 5.2 0.4 10.0 0.1 3.0 1 1 2 3 3 3 2 Leucine-rich repeat Nicastrin PF05450.13 001170242.2_18526001_1 - 2.1e-94 315.3 0.2 2.9e-94 314.8 0.2 1.2 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.15 001170242.2_18526001_1 - 4.2e-10 39.5 0.0 6.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PK PF00224.19 170004.2_18524001_2 - 7e-162 538.1 2.4 9.8e-162 537.6 2.4 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.14 170004.2_18524001_2 - 1.6e-35 121.7 0.7 4.1e-35 120.4 0.2 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.12 170004.2_18524001_2 - 0.0072 15.3 0.6 0.018 14.0 0.4 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Arf PF00025.19 170002.3_18524001_3 - 1.3e-62 210.2 0.0 1.8e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.18 170002.3_18524001_3 - 9.8e-10 38.0 0.3 2.3e-07 30.1 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.11 170002.3_18524001_3 - 1.6e-07 31.4 1.4 2.9e-07 30.6 0.0 2.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.21 170002.3_18524001_3 - 5.7e-06 26.3 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.8 170002.3_18524001_3 - 1.3e-05 24.6 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 170002.3_18524001_3 - 2.7e-05 23.5 0.0 4.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.20 170002.3_18524001_3 - 3.3e-05 23.4 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ras family adh_short PF00106.23 001275902.1_18523001_2 - 1.2e-42 145.4 0.8 1.6e-42 145.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001275902.1_18523001_2 - 9.9e-27 93.9 0.2 1.3e-26 93.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001275902.1_18523001_2 - 3.2e-09 36.8 0.3 5.3e-09 36.1 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001275902.1_18523001_2 - 9.1e-06 25.2 0.2 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TfuA PF07812.10 001275902.1_18523001_2 - 0.37 10.4 2.3 1.6 8.4 1.8 2.0 1 1 0 2 2 2 0 TfuA-like protein MFS_1 PF07690.14 001300531.1_18528001_1 - 3.4e-22 78.7 18.3 2.9e-19 69.1 15.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 001300531.1_18528001_1 - 1e-21 77.3 16.1 1.5e-21 76.7 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.23 142440.3_18526001_3 - 1.5e-20 73.5 0.0 6.3e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.16 142440.3_18526001_3 - 4.9e-13 48.8 4.9 9.8e-13 47.8 4.9 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PX PF00787.22 142440.3_18526001_3 - 6.2e-13 48.6 0.7 1.5e-12 47.4 0.7 1.6 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.15 142440.3_18526001_3 - 2.2e-12 46.7 0.0 4.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Jnk-SapK_ap_N PF09744.7 141982.3_18522001_2 - 0.67 10.0 13.0 0.38 10.8 11.0 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 MerR-DNA-bind PF09278.9 141982.3_18522001_2 - 0.84 10.1 6.2 0.79 10.2 1.1 2.9 3 0 0 3 3 3 0 MerR, DNA binding EB PF01683.16 001275584.1_18526001_3 - 1.2e-36 124.6 130.8 3.5e-07 30.2 2.0 10.7 4 3 6 10 10 10 9 EB module UQ_con PF00179.24 001275649.1_18524001_2 - 2.3e-52 176.2 0.0 3.8e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001275649.1_18524001_2 - 0.058 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RWD domain Gly-rich_Ago1 PF12764.5 169764.3_18522001_1 - 0.00042 20.9 0.4 0.00042 20.9 0.4 1.7 2 0 0 2 2 2 1 Glycine-rich region of argonaut WD40 PF00400.30 143463.5_18526001_1 - 8.7e-19 67.4 16.7 1.7e-08 34.8 0.3 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 143463.5_18526001_1 - 2.6e-05 24.3 1.7 1.6 8.9 0.0 4.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 143463.5_18526001_1 - 0.00065 19.5 2.5 0.0019 17.9 0.5 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.4 001300465.1_18522001_3 - 7.9e-14 51.5 6.4 1.4e-13 50.8 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 001300465.1_18522001_3 - 5e-11 42.6 3.5 8.9e-11 41.8 3.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001300465.1_18522001_3 - 7.4e-10 38.2 5.0 7.8e-10 38.2 3.4 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001300465.1_18522001_3 - 1.2e-09 37.7 6.5 2e-09 37.0 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001300465.1_18522001_3 - 7.2e-09 35.2 7.3 7.2e-09 35.2 7.3 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001300465.1_18522001_3 - 9e-07 28.6 5.3 1.4e-06 28.0 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 001300465.1_18522001_3 - 9.4e-07 28.7 0.5 1.4e-06 28.1 0.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.4 001300465.1_18522001_3 - 9.9e-07 28.4 3.6 1.6e-06 27.8 3.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.4 001300465.1_18522001_3 - 5.6e-06 26.0 2.8 9e-06 25.3 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001300465.1_18522001_3 - 3.2e-05 23.7 5.1 6e-05 22.9 5.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger C1_2 PF03107.14 001300465.1_18522001_3 - 0.005 17.0 1.8 0.0088 16.2 0.3 1.9 2 0 0 2 2 2 1 C1 domain zf-Nse PF11789.6 001300465.1_18522001_3 - 0.0075 15.9 2.1 0.013 15.2 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.3 001300465.1_18522001_3 - 0.017 14.6 3.1 0.03 13.8 3.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.12 001300465.1_18522001_3 - 0.02 14.6 0.4 0.056 13.2 0.4 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING-like PF08746.9 001300465.1_18522001_3 - 0.029 14.6 3.5 0.043 14.0 3.5 1.3 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.5 001300465.1_18522001_3 - 0.037 14.0 4.8 0.078 13.0 4.8 1.6 1 1 0 1 1 1 0 RING-variant domain zf-P11 PF03854.12 001300465.1_18522001_3 - 0.11 12.0 4.0 0.18 11.4 1.6 2.0 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.4 001300465.1_18522001_3 - 0.25 11.0 5.1 0.51 10.0 5.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PAN_1 PF00024.24 143476.3_18526001_2 - 1.7e-30 104.7 18.2 2.3e-13 49.8 2.7 3.4 3 0 0 3 3 3 3 PAN domain PAN_3 PF08277.10 143476.3_18526001_2 - 3.7e-05 23.3 7.1 0.0034 17.0 0.1 3.6 3 0 0 3 3 3 3 PAN-like domain PAN_4 PF14295.4 143476.3_18526001_2 - 0.008 15.9 14.0 0.4 10.5 0.4 4.0 4 0 0 4 4 4 3 PAN domain Zip PF02535.20 170443.3_18524001_3 - 1.7e-70 237.8 0.1 2e-70 237.6 0.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter IF-2B PF01008.15 143495.3_18523001_2 - 9.8e-65 218.4 0.0 1.2e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Arf PF00025.19 001300297.1_18524001_2 - 1.1e-43 148.5 0.0 1.6e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.20 001300297.1_18524001_2 - 3.6e-15 55.8 0.0 6.1e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001300297.1_18524001_2 - 2.2e-14 53.6 0.0 3.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.10 001300297.1_18524001_2 - 3e-07 29.9 0.0 4.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.18 001300297.1_18524001_2 - 6.1e-07 28.8 0.1 6.6e-05 22.1 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.8 001300297.1_18524001_2 - 0.00043 19.6 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001300297.1_18524001_2 - 0.00077 19.4 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Homeobox PF00046.27 169958.2_18523001_1 - 9e-20 70.1 6.8 1.3e-19 69.6 5.2 2.0 2 0 0 2 2 2 1 Homeobox domain B56 PF01603.18 001144600.2_18524001_3 - 2.7e-198 658.9 11.7 3.5e-198 658.5 11.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF349 PF03993.10 001144600.2_18524001_3 - 7.3e-05 22.9 5.2 0.00023 21.3 2.9 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF349) PSDC PF12588.6 001144600.2_18524001_3 - 0.036 13.9 0.2 0.32 10.8 0.1 2.4 2 0 0 2 2 2 0 Phophatidylserine decarboxylase MGAT2 PF05060.12 001014684.2_18526001_2 - 2e-161 536.7 11.5 2.4e-161 536.4 11.5 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) MGAT2 PF05060.12 001276167.1_18527001_1 - 2.4e-155 516.7 16.2 2.2e-98 329.4 4.4 2.1 1 1 1 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) Ribosomal_L32e PF01655.16 170460.2_18522001_1 - 1.2e-53 179.9 1.9 1.6e-53 179.5 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 LEDGF PF11467.6 001276170.1_18524001_2 - 2.1e-41 140.2 0.5 4.2e-41 139.2 0.1 1.8 2 0 0 2 2 2 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.15 001276170.1_18524001_2 - 3.6e-14 52.8 0.1 1.3e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 PWWP domain zf-C2H2_4 PF13894.4 169587.2_18529001_1 - 7.4e-36 119.6 104.9 0.0015 19.1 0.8 16.1 16 0 0 16 16 16 15 C2H2-type zinc finger zf-C2H2 PF00096.24 169587.2_18529001_1 - 4.9e-35 117.9 102.8 0.00053 20.2 2.0 15.7 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 169587.2_18529001_1 - 2.1e-18 65.7 97.1 7.6e-08 32.3 0.4 15.2 15 2 0 15 15 15 9 Zinc-finger double domain zf-C2H2_jaz PF12171.6 169587.2_18529001_1 - 3.2e-11 43.1 75.8 0.43 10.8 0.1 15.4 16 0 0 16 16 16 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 169587.2_18529001_1 - 6.3e-11 41.8 84.5 0.00034 20.3 0.2 13.3 14 0 0 14 14 14 8 C2H2-type zinc finger zf-C2H2_8 PF15909.3 169587.2_18529001_1 - 1.5e-09 37.9 36.7 0.01 15.9 4.7 8.6 4 2 4 8 8 8 4 C2H2-type zinc ribbon zf-Di19 PF05605.10 169587.2_18529001_1 - 0.0065 16.6 71.2 0.083 13.1 1.3 9.4 8 2 2 10 10 10 5 Drought induced 19 protein (Di19), zinc-binding Hypoth_Ymh PF09509.8 206461.2_18524001_3 - 0.15 11.8 0.9 6.4 6.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (Hypoth_ymh) HLH PF00010.24 079779.3_18523001_1 - 3.9e-13 49.0 0.6 6.6e-13 48.3 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.11 079779.3_18523001_1 - 1.3e-07 31.5 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Hairy Orange TLE_N PF03920.13 206575.3_18527001_3 - 6.4e-64 213.8 4.8 6.4e-64 213.8 4.8 1.6 2 0 0 2 2 2 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.30 206575.3_18527001_3 - 1.5e-19 69.8 15.4 0.0025 18.5 0.4 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 206575.3_18527001_3 - 1.1e-08 35.1 0.0 0.099 12.8 0.0 4.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.3 206575.3_18527001_3 - 0.043 13.0 0.0 7.1 5.7 0.1 2.5 2 1 1 3 3 3 0 WD40-like domain TLE_N PF03920.13 001202365.2_18526001_3 - 6.4e-64 213.8 4.8 6.4e-64 213.8 4.8 1.6 2 0 0 2 2 2 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.30 001202365.2_18526001_3 - 1.5e-19 69.8 15.4 0.0025 18.5 0.4 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001202365.2_18526001_3 - 1.1e-08 35.1 0.0 0.099 12.8 0.0 4.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.3 001202365.2_18526001_3 - 0.043 13.0 0.0 7.1 5.7 0.1 2.5 2 1 1 3 3 3 0 WD40-like domain zf-C2H2 PF00096.24 079625.3_18527001_1 - 2.4e-48 159.8 84.5 5.6e-05 23.2 0.5 12.5 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 079625.3_18527001_1 - 1.4e-35 120.0 78.4 4.9e-09 36.1 1.0 13.6 13 1 0 13 13 13 8 Zinc-finger double domain zf-C2H2_4 PF13894.4 079625.3_18527001_1 - 9e-32 106.9 89.3 0.00017 22.0 0.9 13.0 13 0 0 13 13 12 11 C2H2-type zinc finger zf-C2H2_6 PF13912.4 079625.3_18527001_1 - 1.1e-22 79.3 62.2 1.1e-05 25.2 0.4 12.6 12 0 0 12 12 12 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 079625.3_18527001_1 - 7.1e-18 64.3 59.9 0.00055 20.0 0.6 11.6 12 0 0 12 12 11 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 079625.3_18527001_1 - 8.7e-14 51.3 64.7 0.012 15.9 0.3 12.3 12 0 0 12 12 12 8 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 079625.3_18527001_1 - 3.4e-09 36.1 37.8 0.5 10.0 0.3 10.4 10 0 0 10 10 10 6 zinc-finger C2H2-type zf-H2C2_5 PF13909.4 079625.3_18527001_1 - 0.014 15.0 0.7 0.014 15.0 0.7 8.3 9 1 0 9 9 9 0 C2H2-type zinc-finger domain BolA PF01722.16 079625.3_18527001_1 - 0.014 15.5 3.7 7.3 6.8 0.1 4.8 4 1 0 4 4 4 0 BolA-like protein DUF3108 PF11306.6 079625.3_18527001_1 - 0.05 13.5 0.3 0.088 12.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) zf-BED PF02892.13 079625.3_18527001_1 - 0.18 11.7 0.1 0.18 11.7 0.1 7.0 6 2 3 9 9 9 0 BED zinc finger zf-C2H2_2 PF12756.5 079625.3_18527001_1 - 0.61 10.3 67.5 0.81 9.9 0.3 10.1 1 1 7 9 9 9 0 C2H2 type zinc-finger (2 copies) Voltage_CLC PF00654.18 001104282.3_18528001_2 - 5.5e-85 285.6 30.3 5.5e-85 285.6 30.3 1.8 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.26 001104282.3_18528001_2 - 0.003 17.8 3.5 1.5 9.2 0.1 3.0 3 0 0 3 3 3 2 CBS domain Thymidylate_kin PF02223.15 001104282.3_18528001_2 - 0.043 13.4 0.3 0.092 12.3 0.3 1.5 1 0 0 1 1 1 0 Thymidylate kinase HMG_box PF00505.17 001104373.2_18529001_2 - 2.1e-16 59.9 4.4 5.6e-16 58.6 4.4 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001104373.2_18529001_2 - 4.3e-07 30.3 3.0 4.3e-07 30.3 3.0 2.3 2 0 0 2 2 2 1 HMG-box domain EBV-NA3 PF05009.10 001104373.2_18529001_2 - 5.2 6.4 10.2 0.28 10.6 4.2 1.9 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) His_Phos_1 PF00300.20 001104427.1_18525001_2 - 3.5e-21 75.7 0.0 9e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.4 001104427.1_18525001_2 - 2.1e-14 52.9 0.1 4.3e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001104427.1_18525001_2 - 0.009 15.5 0.1 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 SH3 domain Trypsin PF00089.24 001104440.5_18523001_3 - 1.9e-65 220.7 0.0 2.6e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001104440.5_18523001_3 - 2.5e-10 40.6 0.0 4.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001104440.5_18523001_3 - 1.3e-05 26.0 0.0 2.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain MADF_DNA_bdg PF10545.7 001104450.2_18524001_2 - 1.5e-20 73.2 1.2 1.5e-20 73.2 1.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.4 001104450.2_18524001_2 - 0.00018 21.7 0.1 0.00037 20.7 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DnaJ_C PF01556.16 169521.2_18524001_2 - 6e-39 133.4 1.1 8.3e-39 132.9 1.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 169521.2_18524001_2 - 4.4e-26 90.6 1.2 7.6e-26 89.9 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.17 169521.2_18524001_2 - 5.6e-15 55.3 19.6 1.1e-14 54.4 19.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.3 169521.2_18524001_2 - 0.0051 16.6 9.2 0.047 13.5 1.0 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.17 169521.2_18524001_2 - 0.52 10.2 9.1 2.5 8.0 2.3 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.3 169521.2_18524001_2 - 9.3 6.3 11.9 0.36 10.9 2.1 2.5 1 1 1 2 2 2 0 zinc RING finger of MSL2 BSD PF03909.15 001300421.1_18529001_1 - 6.7e-13 48.3 0.1 1.3e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 BSD domain EHD_N PF16880.3 176497.2_18529001_1 - 1.6e-08 34.1 0.4 3.2e-08 33.2 0.4 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.21 176497.2_18529001_1 - 5.2e-06 26.5 1.0 8.5e-05 22.5 0.0 2.9 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.21 176497.2_18529001_1 - 0.0066 16.4 0.0 0.02 14.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GST_N_3 PF13417.4 141637.3_18522001_3 - 1.4e-17 63.7 0.1 2.5e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 141637.3_18522001_3 - 1.9e-12 47.2 0.0 3.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 141637.3_18522001_3 - 4.4e-12 46.0 0.0 8.7e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 141637.3_18522001_3 - 4.1e-07 30.0 0.0 7.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 141637.3_18522001_3 - 3e-05 24.0 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 141637.3_18522001_3 - 0.00094 19.0 0.0 0.0022 17.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 141638.3_18523001_3 - 1.2e-18 67.1 0.0 2.3e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 141638.3_18523001_3 - 7.1e-14 51.8 0.0 1.4e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 141638.3_18523001_3 - 1.5e-13 50.7 0.0 3.1e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 141638.3_18523001_3 - 6.5e-07 29.4 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 141638.3_18523001_3 - 0.00015 21.7 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 141638.3_18523001_3 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 169286.2_18525001_2 - 4.1e-18 65.4 0.0 7.1e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 169286.2_18525001_2 - 2.7e-13 49.9 0.8 3.8e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 169286.2_18525001_2 - 5e-13 49.0 0.0 9.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 169286.2_18525001_2 - 1.9e-06 27.9 0.0 4.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 169286.2_18525001_2 - 0.00049 20.1 0.0 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 169286.2_18525001_2 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ras PF00071.20 057351.5_18524001_1 - 4e-56 189.0 0.1 5.8e-56 188.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 057351.5_18524001_1 - 2.3e-20 72.9 0.0 4.1e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 057351.5_18524001_1 - 2.3e-08 33.5 0.0 3.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 057351.5_18524001_1 - 3.2e-06 26.7 0.1 1.1e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 057351.5_18524001_1 - 7.7e-05 22.5 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 057351.5_18524001_1 - 0.00017 21.5 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.16 057351.5_18524001_1 - 0.1 12.0 0.1 0.39 10.1 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Dsh_C PF12316.6 057351.5_18524001_1 - 5.5 7.2 5.5 8.6 6.6 5.5 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PTB PF08416.11 001170099.3_18529001_1 - 8.6e-40 135.8 0.0 1.4e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.22 001170099.3_18529001_1 - 4.3e-10 39.4 0.0 1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 SH2 domain PTB PF08416.11 001170098.2_18529001_1 - 7.6e-40 136.0 0.0 1.2e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.22 001170098.2_18529001_1 - 3.7e-10 39.6 0.0 9.3e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain MPC PF03650.11 169294.2_18523001_3 - 1.5e-39 134.4 0.2 2e-39 134.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) CAP_N PF01213.17 169294.2_18523001_3 - 0.16 11.3 3.1 0.23 10.7 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MPC PF03650.11 001170100.2_18523001_3 - 1.4e-39 134.5 0.2 2.1e-39 133.9 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) CAP_N PF01213.17 001170100.2_18523001_3 - 0.085 12.2 2.2 0.12 11.7 2.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Arm PF00514.21 176437.2_18526001_3 - 9.6e-73 238.1 11.7 1.1e-10 41.0 0.4 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.4 176437.2_18526001_3 - 2.5e-21 75.6 0.4 1.4e-07 31.7 0.4 5.4 5 0 0 5 5 5 4 HEAT-like repeat Arm_3 PF16186.3 176437.2_18526001_3 - 2.7e-21 74.7 1.8 7.1e-21 73.4 1.8 1.7 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.18 176437.2_18526001_3 - 1.2e-19 70.3 9.5 3.2e-19 69.0 9.5 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.20 176437.2_18526001_3 - 1e-15 56.3 0.2 0.0003 20.6 0.0 6.4 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.4 176437.2_18526001_3 - 5.1e-15 55.5 0.3 0.0072 16.6 0.0 5.3 2 2 3 5 5 5 5 HEAT repeats Arm_2 PF04826.11 176437.2_18526001_3 - 4.3e-05 23.0 1.0 0.063 12.6 0.1 3.1 2 1 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.6 176437.2_18526001_3 - 0.0026 17.8 0.1 6.4 6.8 0.0 3.6 3 0 0 3 3 3 1 V-ATPase subunit H Cnd1 PF12717.5 176437.2_18526001_3 - 0.0027 17.6 0.1 0.33 10.8 0.0 3.5 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Pneumo_phosprot PF02478.14 176437.2_18526001_3 - 0.0031 17.0 3.1 0.0049 16.3 3.1 1.2 1 0 0 1 1 1 1 Pneumovirus phosphoprotein ParcG PF10274.7 176437.2_18526001_3 - 0.015 15.2 0.3 0.24 11.3 0.0 2.6 3 0 0 3 3 3 0 Parkin co-regulated protein Cornifin PF02389.13 079570.4_18523001_1 - 0.0012 18.9 12.7 0.0012 18.9 12.7 2.2 1 1 1 2 2 2 2 Cornifin (SPRR) family Jiv90 PF14901.4 142232.2_18522001_2 - 0.071 13.2 0.7 0.13 12.4 0.7 1.3 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone HEM4 PF02602.13 142232.2_18522001_3 - 2.9e-28 98.7 0.0 3.6e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD p450 PF00067.20 001300310.1_18525001_2 - 9.6e-71 238.8 0.0 1.2e-70 238.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Globin PF00042.20 169679.2_18522001_2 - 9.5e-15 55.0 0.0 1.6e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Globin DEAD PF00270.27 001275450.1_18528001_2 - 3.4e-54 183.1 0.0 9.6e-54 181.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001275450.1_18528001_2 - 7.1e-30 103.5 0.0 2e-29 102.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001275450.1_18528001_2 - 1.5e-05 24.9 0.0 3.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TACC PF05010.12 058085.5_18529001_1 - 9.5e-59 198.4 39.7 9.5e-59 198.4 39.7 2.7 2 1 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) JAB PF01398.19 141232.3_18523001_2 - 7.6e-21 74.2 0.2 1.5e-20 73.2 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.4 141232.3_18523001_2 - 1.7e-20 73.4 0.5 2.7e-20 72.8 0.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function C2 PF00168.28 141196.2_18526001_2 - 2e-25 88.9 0.0 2.3e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain Utp21 PF04192.10 142027.4_18526001_1 - 5.2e-64 215.8 0.3 8e-64 215.2 0.3 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.30 142027.4_18526001_1 - 2.5e-18 66.0 14.4 1.1e-07 32.3 0.1 8.7 9 0 0 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 142027.4_18526001_1 - 1.2e-15 57.5 0.1 2.8e-05 24.2 0.0 5.3 3 3 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 142027.4_18526001_1 - 0.0023 17.7 0.0 0.23 11.2 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 142027.4_18526001_1 - 0.012 14.5 0.0 2.3 7.0 0.0 2.6 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.10 142027.4_18526001_1 - 0.15 9.9 0.0 0.25 9.1 0.0 1.3 1 0 0 1 1 1 0 IKI3 family PNRC PF15365.4 176425.3_18529001_3 - 6.6e-16 58.5 0.9 6.6e-16 58.5 0.9 3.6 3 1 0 3 3 3 2 Proline-rich nuclear receptor coactivator DUF410 PF04190.11 001300227.1_18524001_3 - 8.8e-63 212.3 0.0 1.1e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) PWWP PF00855.15 142066.2_18522001_1 - 4.5e-09 36.5 0.0 1.9e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 PWWP domain 7tm_1 PF00001.19 001276113.1_18524001_2 - 9.5e-52 175.7 25.7 1.4e-51 175.2 25.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001276113.1_18524001_2 - 6.7e-13 48.5 24.1 8.6e-13 48.1 24.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001276113.1_18524001_2 - 5.8e-10 38.8 16.8 5.8e-10 38.8 16.8 2.1 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.13 001276113.1_18524001_2 - 0.31 10.9 15.2 0.075 12.9 11.0 2.0 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa Gaa1 PF04114.12 001276113.1_18524001_2 - 1.2 8.0 14.3 0.038 12.9 1.5 2.2 1 1 1 2 2 2 0 Gaa1-like, GPI transamidase component Forkhead PF00250.16 001170291.1_18529001_2 - 1.4e-35 121.3 0.1 4e-35 119.9 0.1 1.8 1 0 0 1 1 1 1 Forkhead domain Forkhead_N PF08430.10 001170291.1_18529001_2 - 7.2e-22 78.3 55.0 7.2e-22 78.3 55.0 5.2 3 1 1 4 4 4 1 Forkhead N-terminal region Serglycin PF04360.10 001170291.1_18529001_2 - 0.0001 22.2 7.2 0.0001 22.2 7.2 2.2 3 0 0 3 3 3 1 Serglycin EamA PF00892.18 001316533.1_18528001_1 - 0.00031 20.8 23.3 0.0013 18.8 4.8 2.8 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.13 001316533.1_18528001_1 - 0.0004 19.5 0.4 0.0004 19.5 0.4 2.5 2 1 1 3 3 3 2 Nucleotide-sugar transporter eIF-3_zeta PF05091.10 079739.4_18525001_3 - 2.3e-214 713.1 0.0 2.7e-214 712.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.7 079739.4_18525001_3 - 0.00037 20.0 0.0 0.0045 16.4 0.0 2.1 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Ran_BP1 PF00638.16 001275952.1_18524001_2 - 1.2e-08 35.1 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain DUF778 PF05608.10 001275952.1_18524001_2 - 0.069 13.3 6.0 5.7 7.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF778) Kinesin_assoc PF16183.3 001275952.1_18524001_2 - 1.2 9.1 10.1 6.7 6.7 10.1 2.2 1 1 0 1 1 1 0 Kinesin-associated zf-RING_2 PF13639.4 169139.2_18527001_2 - 1.9e-13 50.3 7.9 6.7e-13 48.5 7.9 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 169139.2_18527001_2 - 8.6e-09 34.8 4.8 8.6e-09 34.8 4.8 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.5 169139.2_18527001_2 - 8.9e-08 32.2 4.9 2.9e-07 30.5 4.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.20 169139.2_18527001_2 - 9.3e-08 32.0 0.0 2.2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.4 169139.2_18527001_2 - 1.3e-06 28.1 3.9 3.5e-06 26.7 3.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.4 169139.2_18527001_2 - 4e-06 26.4 6.7 9.8e-06 25.2 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 169139.2_18527001_2 - 5e-06 26.2 5.8 1.3e-05 24.9 5.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 169139.2_18527001_2 - 0.0004 20.0 4.1 0.0004 20.0 4.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 169139.2_18527001_2 - 0.00063 19.4 4.9 0.0015 18.2 4.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 169139.2_18527001_2 - 0.00064 19.6 4.3 0.0078 16.1 2.3 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.5 169139.2_18527001_2 - 0.0013 18.6 1.3 0.0013 18.6 1.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.6 169139.2_18527001_2 - 0.4 10.8 4.5 2.1 8.4 4.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Pkinase PF00069.23 001275384.1_18529001_3 - 3.1e-74 249.6 0.0 4.5e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001275384.1_18529001_3 - 1.6e-47 161.8 0.0 3.1e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.26 001275384.1_18529001_3 - 1.1e-23 83.3 0.1 2.7e-23 82.0 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.4 001275384.1_18529001_3 - 8.9e-05 21.8 0.1 0.0017 17.6 0.1 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001275384.1_18529001_3 - 0.0044 16.9 0.0 0.97 9.2 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DSHCT PF08148.10 001275384.1_18529001_3 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Reticulon PF02453.15 142313.3_18523001_2 - 1.6e-06 28.0 7.3 2.5e-06 27.4 7.3 1.2 1 0 0 1 1 1 1 Reticulon SecE PF00584.18 142313.3_18523001_2 - 1.9 8.3 5.5 6.4 6.6 0.5 2.4 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.20 080492.3_18526001_1 - 7.3e-30 102.5 0.1 1.4e-13 50.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.9 080492.3_18526001_1 - 1.5e-22 79.3 0.0 3.5e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_occluded PF16842.3 080492.3_18526001_1 - 0.017 14.9 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif APG6 PF04111.10 080492.3_18526001_1 - 4.7 6.4 22.4 7.2 5.8 22.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.4 080492.3_18526001_1 - 6.4 5.9 6.0 13 4.9 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DnaJ PF00226.29 142928.3_18523001_1 - 4.5e-14 52.2 0.0 1.1e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain SF3a60_bindingd PF12108.6 142928.3_18523001_1 - 0.05 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Homeobox PF00046.27 169730.3_18529001_1 - 2.9e-19 68.5 6.4 2.9e-19 68.5 6.4 2.1 2 0 0 2 2 2 1 Homeobox domain TAF6_C PF07571.11 001300252.1_18525001_3 - 1.2e-26 92.7 0.0 1.2e-24 86.3 0.0 2.6 2 0 0 2 2 2 2 TAF6 C-terminal HEAT repeat domain TAF PF02969.15 001300252.1_18525001_3 - 0.027 14.5 0.0 0.074 13.1 0.0 1.7 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) BK_channel_a PF03493.16 001014652.3_18529001_3 - 2.7e-38 130.0 0.0 6e-38 128.9 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.29 001014652.3_18529001_3 - 4.6e-17 61.9 20.8 1.2e-16 60.5 20.8 1.6 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.14 001014652.3_18529001_3 - 2e-14 53.2 5.4 2e-14 53.2 5.4 3.0 3 0 0 3 3 3 1 Ion channel TrkA_N PF02254.16 001014652.3_18529001_3 - 0.055 13.6 0.1 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Pmp3 PF01679.15 001170132.2_18528001_1 - 0.004 17.2 0.1 0.01 15.9 0.1 1.7 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RRM_1 PF00076.20 001170132.2_18528001_2 - 7.1e-28 96.1 0.2 3.9e-17 61.7 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.9 001170132.2_18528001_2 - 0.0027 17.6 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.4 001170132.2_18528001_2 - 0.041 13.3 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001170132.2_18528001_2 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Ion_trans_2 PF07885.14 142469.2_18524001_1 - 2.5e-28 97.7 19.3 8.2e-16 57.6 1.3 3.5 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.29 142469.2_18524001_1 - 4.8e-06 25.8 1.6 0.0015 17.7 0.0 2.3 1 1 0 2 2 2 2 Ion transport protein UPF0233 PF06781.10 142469.2_18524001_1 - 0.011 15.6 0.5 1 9.3 0.6 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Rib_5-P_isom_A PF06026.12 142469.2_18524001_1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Fibrillarin PF01269.15 141979.2_18523001_3 - 1.6e-77 259.6 0.0 1.9e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin PCMT PF01135.17 141979.2_18523001_3 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Jagunal PF07086.10 169103.2_18524001_3 - 1.4e-75 253.5 1.8 1.8e-75 253.0 1.8 1.2 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis zf-C2H2_4 PF13894.4 001275372.1_18529001_1 - 1e-08 35.1 36.6 0.021 15.5 2.3 6.7 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.24 001275372.1_18529001_1 - 1e-06 28.7 41.2 0.0088 16.3 4.5 6.7 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 001275372.1_18529001_1 - 7.9e-05 22.7 20.9 0.017 15.3 1.5 5.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001275372.1_18529001_1 - 0.0003 20.5 18.7 0.21 11.5 0.1 5.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.5 001275372.1_18529001_1 - 0.0013 18.9 25.4 0.27 11.5 0.9 6.3 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.3 001275372.1_18529001_1 - 0.02 15.0 13.9 0.38 11.0 0.7 3.6 3 1 0 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.4 001275372.1_18529001_1 - 0.025 14.9 0.3 0.025 14.9 0.3 6.5 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_2 PF12756.5 001275372.1_18529001_1 - 0.08 13.1 20.3 2.3 8.5 0.0 6.1 4 2 2 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.10 001275372.1_18529001_1 - 0.083 13.1 22.8 0.013 15.6 5.2 3.8 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding AKAP95 PF04988.10 001275372.1_18529001_1 - 0.11 12.6 3.3 0.9 9.6 0.1 2.7 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_9 PF16293.3 001275372.1_18529001_1 - 0.21 11.3 13.4 11 5.8 0.1 5.2 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) NPR1_interact PF15699.3 001275372.1_18529001_1 - 0.76 10.3 6.8 2.9 8.4 6.8 2.0 1 0 0 1 1 1 0 NPR1 interacting DnaJ PF00226.29 141506.3_18522001_1 - 5e-23 80.9 0.6 1.1e-22 79.8 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain PriCT_2 PF08707.9 141506.3_18522001_1 - 0.077 13.2 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) AICARFT_IMPCHas PF01808.16 001202357.1_18525001_1 - 2.5e-91 306.1 0.0 3.1e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.20 001202357.1_18525001_1 - 9.6e-25 86.5 0.0 1.7e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Trypsin PF00089.24 001276194.1_18523001_2 - 1.4e-43 149.1 0.0 2.1e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin CLIP PF12032.6 001276194.1_18523001_2 - 1.8e-10 40.8 4.6 4.4e-10 39.5 4.6 1.7 1 0 0 1 1 1 1 Regulatory CLIP domain of proteinases Trypsin_2 PF13365.4 001276194.1_18523001_2 - 5.2e-05 24.0 0.1 0.00014 22.7 0.1 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.13 001276194.1_18523001_2 - 0.001 18.6 0.0 0.97 8.8 0.0 2.2 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.9 001276194.1_18523001_2 - 0.004 17.4 0.1 0.038 14.2 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) IF-2B PF01008.15 170551.3_18524001_1 - 3.8e-83 278.8 0.1 4.5e-83 278.6 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PBP_GOBP PF01395.20 001300260.1_18522001_2 - 1.9e-22 79.4 0.6 1.9e-22 79.4 0.6 1.5 2 0 0 2 2 2 1 PBP/GOBP family PBP_GOBP PF01395.20 079518.3_18522001_3 - 1.4e-21 76.6 0.1 1.8e-21 76.3 0.1 1.1 1 0 0 1 1 1 1 PBP/GOBP family MADF_DNA_bdg PF10545.7 143501.4_18524001_1 - 6.2e-19 68.0 0.7 1.6e-18 66.7 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.4 143501.4_18524001_1 - 0.014 15.7 1.9 0.036 14.3 1.9 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Tup_N PF08581.8 143501.4_18524001_1 - 0.048 13.8 0.2 0.048 13.8 0.2 2.8 2 1 1 3 3 3 0 Tup N-terminal DUF2031 PF09592.8 143501.4_18524001_1 - 0.84 9.0 9.1 0.14 11.6 5.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) Homeobox PF00046.27 001316542.1_18529001_1 - 4.8e-18 64.6 12.2 9.1e-18 63.7 10.8 2.1 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.9 001316542.1_18529001_1 - 0.83 9.5 4.8 0.15 11.9 0.6 1.9 2 0 0 2 2 2 0 Homeobox KN domain Tim44 PF04280.13 142529.3_18525001_3 - 3.4e-45 153.6 0.0 9.1e-45 152.2 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain DUF3251 PF11622.6 142529.3_18525001_3 - 0.22 11.0 1.4 0.37 10.3 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) IncA PF04156.12 142529.3_18525001_3 - 0.39 10.3 4.9 0.71 9.5 4.9 1.4 1 0 0 1 1 1 0 IncA protein Trypsin PF00089.24 001202361.3_18523001_1 - 1.8e-65 220.7 0.0 2.5e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001202361.3_18523001_1 - 2.4e-10 40.7 0.0 4.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001202361.3_18523001_1 - 1.2e-05 26.1 0.0 2.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain RrnaAD PF00398.18 143403.4_18523001_3 - 2.2e-64 217.0 0.1 3.1e-64 216.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.4 143403.4_18523001_3 - 1.9e-06 28.4 0.0 3.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 143403.4_18523001_3 - 9.2e-05 22.1 0.0 0.00019 21.1 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.18 143403.4_18523001_3 - 0.00026 20.2 0.0 0.0006 19.0 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.10 143403.4_18523001_3 - 0.0029 18.1 0.0 0.006 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.12 143403.4_18523001_3 - 0.015 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.10 143403.4_18523001_3 - 0.026 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.15 143403.4_18523001_3 - 0.038 13.3 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.16 143403.4_18523001_3 - 0.051 12.6 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_23 PF13489.4 143403.4_18523001_3 - 0.054 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.10 143403.4_18523001_3 - 0.057 14.0 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.5 143403.4_18523001_3 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.4 143403.4_18523001_3 - 0.11 12.2 0.0 0.61 9.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Trypsin PF00089.24 143404.2_18523001_1 - 3e-45 154.6 0.0 3.6e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 143404.2_18523001_1 - 0.00014 22.6 0.0 0.00024 21.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain FERM_M PF00373.16 001170255.1_18528001_2 - 1.4e-19 70.5 0.0 1.4e-19 70.5 0.0 3.0 3 0 0 3 3 3 1 FERM central domain PAT1 PF09770.7 001170255.1_18528001_2 - 0.016 13.4 19.9 0.024 12.8 19.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TERB2 PF15101.4 001170255.1_18528001_2 - 0.075 13.0 9.8 0.15 12.0 9.8 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Glu_synthase PF01645.15 001170255.1_18528001_2 - 7.3 5.5 10.1 0.54 9.2 0.1 2.1 2 0 0 2 2 2 0 Conserved region in glutamate synthase JHBP PF06585.9 001300596.1_18523001_2 - 1.8e-63 213.8 0.2 2.4e-63 213.4 0.2 1.1 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) WD40 PF00400.30 143103.4_18523001_3 - 2.6e-07 31.1 5.9 1.1e-05 25.9 0.7 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 143103.4_18523001_3 - 0.0033 17.6 0.0 0.43 10.8 0.0 3.1 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.5 001275731.1_18528001_3 - 3.2e-41 139.7 0.3 1.9e-11 44.2 0.0 5.7 4 1 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001275731.1_18528001_3 - 2.7e-33 113.8 4.6 3.3e-09 37.0 0.0 7.6 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.28 001275731.1_18528001_3 - 5.9e-26 89.6 1.0 0.0018 18.5 0.0 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.4 001275731.1_18528001_3 - 1.1e-23 80.6 7.5 0.032 14.6 0.0 9.6 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.4 001275731.1_18528001_3 - 9.3e-22 76.6 0.3 3.7e-05 23.8 0.0 5.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Peptidase_M1 PF01433.18 001276136.1_18527001_1 - 7.4e-128 427.0 0.1 9.8e-128 426.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.6 001276136.1_18527001_1 - 8.4e-73 245.5 3.1 8.4e-73 245.5 3.1 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain zf-RING_2 PF13639.4 141602.4_18524001_1 - 1.3e-14 54.0 15.6 1.8e-13 50.3 8.9 2.4 2 0 0 2 2 2 2 Ring finger domain zf-RING_11 PF17123.3 141602.4_18524001_1 - 1.7e-10 40.3 2.7 1.7e-10 40.3 2.7 2.1 2 0 0 2 2 2 1 RING-like zinc finger zinc_ribbon_9 PF14369.4 141602.4_18524001_1 - 1.5e-09 37.8 4.7 1.8e-09 37.6 1.0 2.6 2 0 0 2 2 2 1 zinc-ribbon zf-C3HC4_2 PF13923.4 141602.4_18524001_1 - 1.4e-07 31.1 7.3 1.4e-07 31.1 7.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 141602.4_18524001_1 - 8.8e-07 28.7 2.1 8.8e-07 28.7 2.1 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.23 141602.4_18524001_1 - 5.9e-06 25.9 18.3 2.1e-05 24.1 7.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 141602.4_18524001_1 - 2e-05 24.3 4.6 2e-05 24.3 4.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.5 141602.4_18524001_1 - 4.7e-05 23.5 8.2 4.7e-05 23.5 8.2 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.4 141602.4_18524001_1 - 6.5e-05 22.6 11.4 0.00017 21.2 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 141602.4_18524001_1 - 0.00024 20.8 13.7 0.00089 18.9 5.0 2.6 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 HypA PF01155.17 141602.4_18524001_1 - 0.0081 16.0 2.9 1.5 8.7 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ANAPC11 PF12861.5 141602.4_18524001_1 - 0.02 14.8 6.8 0.02 14.8 3.1 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.4 141602.4_18524001_1 - 0.065 13.0 1.3 0.17 11.6 1.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-H2C2_2 PF13465.4 141602.4_18524001_1 - 0.36 11.2 2.3 12 6.4 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-Nse PF11789.6 141602.4_18524001_1 - 1.2 8.8 5.8 1.3 8.7 3.3 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.10 141602.4_18524001_1 - 2.5 8.3 9.6 24 5.2 0.2 3.5 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_17 PF17120.3 141602.4_18524001_1 - 2.5 7.6 13.0 0.63 9.6 5.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zinc-ribbons_6 PF07191.10 141602.4_18524001_1 - 3.3 7.6 7.0 8.3 6.4 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.5 141602.4_18524001_1 - 4.7 7.2 7.0 6 6.8 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon Neuralized PF07177.10 001170092.3_18527001_2 - 1.1e-93 311.0 0.0 2.1e-47 160.8 0.0 2.9 3 0 0 3 3 3 2 Neuralized zf-C3HC4_3 PF13920.4 001170092.3_18527001_2 - 1.3e-13 50.4 7.3 2.9e-13 49.3 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001170092.3_18527001_2 - 8.6e-05 22.2 6.3 0.00021 20.9 6.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.23 001170092.3_18527001_2 - 0.00013 21.7 7.7 0.00038 20.1 7.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF525 PF04379.12 141283.4_18524001_2 - 6.3e-28 96.7 0.0 1.2e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.9 141283.4_18524001_2 - 5.3e-12 46.0 0.1 3.9e-05 23.9 0.0 2.9 3 0 0 3 3 3 2 Hemimethylated DNA-binding protein YccV like CBP_BcsS PF17036.3 141283.4_18524001_2 - 0.38 10.5 1.3 0.64 9.8 1.3 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsS adh_short_C2 PF13561.4 141306.3_18523001_3 - 1.7e-62 210.9 1.1 2e-62 210.7 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 141306.3_18523001_3 - 2.9e-54 183.4 1.7 3.5e-54 183.1 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 141306.3_18523001_3 - 3.7e-14 52.9 0.4 5.5e-14 52.3 0.4 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.17 141306.3_18523001_3 - 0.097 11.8 1.0 0.15 11.2 0.3 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TipE PF16972.3 001275513.1_18529001_2 - 1.7e-29 103.2 9.5 3.1e-22 79.3 1.4 2.6 2 1 1 3 3 3 2 Na+ channel auxiliary subunit TipE zf-C2H2 PF00096.24 079576.3_18525001_2 - 2.7e-10 40.0 23.3 3e-06 27.2 2.3 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 079576.3_18525001_2 - 8.9e-05 22.2 9.5 0.024 14.4 1.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.5 079576.3_18525001_2 - 0.0005 20.2 19.1 0.053 13.8 1.1 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.4 079576.3_18525001_2 - 0.00097 19.6 10.9 0.0033 18.0 1.7 5.3 7 0 0 7 7 7 2 C2H2-type zinc finger TFIIS_C PF01096.16 079576.3_18525001_2 - 0.042 13.6 0.9 2 8.2 0.0 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_jaz PF12171.6 079576.3_18525001_2 - 0.045 13.9 0.9 0.045 13.9 0.9 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 079576.3_18525001_2 - 0.51 10.4 7.5 4.8 7.3 0.3 3.5 3 0 0 3 3 3 0 Zinc ribbon domain Trypsin PF00089.24 141623.2_18522001_1 - 4.2e-52 177.0 0.7 4.9e-52 176.8 0.7 1.0 1 0 0 1 1 1 1 Trypsin TLD PF07534.14 169038.3_18529001_1 - 2.7e-34 118.2 0.2 4.5e-34 117.5 0.2 1.4 1 0 0 1 1 1 1 TLD LysM PF01476.18 169038.3_18529001_1 - 1.6e-10 40.8 0.0 3.3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 LysM domain Synaphin PF05835.10 164329.3_18528001_1 - 5.7e-42 143.3 24.1 8.4e-42 142.7 24.1 1.2 1 0 0 1 1 1 1 Synaphin protein DOT1 PF08123.11 169143.2_18529001_3 - 1.7e-78 262.7 0.0 3e-78 261.9 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.15 169143.2_18529001_3 - 0.00042 19.7 0.0 0.0014 17.9 0.0 2.0 1 0 0 1 1 1 1 Putative methyltransferase Chibby PF14645.4 001275884.1_18521001_2 - 2e-26 92.6 0.1 2.9e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 Chibby family LIM PF00412.20 169301.3_18526001_1 - 7.7e-43 144.4 51.1 3.8e-13 49.3 4.7 4.5 4 0 0 4 4 4 4 LIM domain COX5A PF02284.14 169436.3_18522001_3 - 3.1e-43 145.8 0.0 4.2e-43 145.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Fis1_TPR_C PF14853.4 142119.3_18526001_2 - 3e-05 23.9 0.2 6.5e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.26 142119.3_18526001_2 - 0.063 13.0 0.4 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.14 001014635.3_18525001_1 - 1.2e-20 74.0 1.4 1.8e-20 73.4 1.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 AAA_5 PF07728.12 001014635.3_18525001_1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SWIRM PF04433.15 001014635.3_18525001_3 - 1.5e-08 34.8 0.1 6.5e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.4 001014635.3_18525001_3 - 1.5e-05 25.0 0.2 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.29 001014635.3_18525001_3 - 0.0001 22.2 0.3 0.00028 20.8 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.8 001014635.3_18525001_3 - 0.02 14.8 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 SLIDE ZZ PF00569.15 001014635.3_18525001_3 - 1.3 8.8 7.7 4.2 7.1 7.7 2.0 1 0 0 1 1 1 0 Zinc finger, ZZ type AT_hook PF02178.17 169840.3_18525001_3 - 0.033 13.9 1.2 0.033 13.9 1.2 2.2 2 0 0 2 2 2 0 AT hook motif bZIP_2 PF07716.13 169840.3_18525001_3 - 0.13 12.3 15.3 0.39 10.7 15.3 1.8 1 0 0 1 1 1 0 Basic region leucine zipper Ribosomal_S30 PF04758.12 169933.2_18522001_3 - 8.5e-30 102.6 11.2 1.2e-29 102.2 11.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.21 169933.2_18522001_3 - 0.0041 16.7 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family BTB PF00651.29 163885.2_18524001_3 - 9.8e-23 80.4 0.2 2.5e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain FLYWCH PF04500.14 163885.2_18524001_3 - 7e-16 58.0 2.4 1.3e-15 57.1 2.4 1.5 1 0 0 1 1 1 1 FLYWCH zinc finger domain Ig_3 PF13927.4 169977.3_18524001_3 - 3.6e-12 46.6 0.8 1.1e-08 35.4 0.0 2.9 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 169977.3_18524001_3 - 3e-10 39.9 0.0 6.3e-07 29.2 0.0 3.3 2 2 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.4 169977.3_18524001_3 - 2.6e-07 30.8 3.2 0.063 13.5 0.3 3.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 169977.3_18524001_3 - 1.9e-06 27.8 1.5 0.17 12.0 0.1 3.8 2 2 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.23 169977.3_18524001_3 - 2.3e-06 27.6 0.5 0.00062 19.8 0.0 3.0 2 2 0 2 2 2 1 Immunoglobulin domain bZIP_Maf PF03131.15 170056.2_18528001_3 - 5.8e-20 71.5 3.4 5.8e-20 71.5 3.4 2.9 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_1 PF00170.19 170056.2_18528001_3 - 8.5e-07 28.9 6.7 8.5e-07 28.9 6.7 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.13 170056.2_18528001_3 - 0.00093 19.1 5.7 0.00093 19.1 5.7 2.2 2 0 0 2 2 2 1 Basic region leucine zipper Exo_endo_phos PF03372.21 170128.2_18526001_2 - 2.9e-10 40.2 0.0 4.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.4 170128.2_18526001_2 - 6e-09 35.4 23.1 4.1e-07 29.5 8.6 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.5 170128.2_18526001_2 - 5.4e-08 32.8 7.2 1.9e-06 28.0 0.9 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.4 170128.2_18526001_2 - 0.046 13.6 5.3 0.99 9.5 0.5 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.31 170128.2_18526001_2 - 0.17 12.3 10.3 2.9 8.6 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Serglycin PF04360.10 170128.2_18526001_2 - 6.1 6.6 6.3 13 5.6 6.3 1.5 1 0 0 1 1 1 0 Serglycin SurA_N_3 PF13624.4 170301.2_18525001_3 - 0.18 11.4 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 SurA N-terminal domain SUI1 PF01253.20 058133.5_18524001_1 - 5.7e-19 68.3 0.2 1.3e-18 67.2 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.18 058133.5_18524001_1 - 1.7e-05 24.5 0.0 4.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 PUA domain Kin17_mid PF10357.7 058133.5_18524001_1 - 0.0038 17.0 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein DUF1947 PF09183.8 058133.5_18524001_1 - 0.067 13.4 0.0 0.28 11.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) UCH PF00443.27 170403.3_18529001_2 - 5.5e-30 104.6 0.9 1.7e-26 93.1 0.9 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 170403.3_18529001_2 - 3.3e-08 33.4 0.1 3.3e-08 33.4 0.1 3.5 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ATP-synt_S1 PF05827.10 170471.3_18524001_2 - 1.5e-34 118.8 0.0 2.4e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.15 170471.3_18524001_2 - 2.3e-05 24.0 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Peptidase_M14 PF00246.22 170512.1_18524001_1 - 2.9e-31 109.2 0.0 4.4e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase JHBP PF06585.9 143275.3_18523001_1 - 2.8e-67 226.3 0.6 3.6e-67 225.9 0.6 1.0 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) RRM_5 PF13893.4 079964.3_18526001_3 - 2.8e-45 152.8 3.2 1.4e-31 108.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 079964.3_18526001_3 - 4e-26 90.5 0.0 1.3e-07 31.1 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 079964.3_18526001_3 - 0.00025 20.7 2.3 5 6.9 0.0 4.4 5 0 0 5 5 5 2 Occluded RNA-recognition motif DUF4776 PF16003.3 142083.4_18527001_1 - 5.2e-167 556.7 33.7 1.3e-164 548.8 33.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4776) DUF4788 PF16032.3 142083.4_18527001_1 - 1.2e-87 292.6 1.2 2.4e-87 291.6 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4788) I-set PF07679.14 143392.3_18527001_1 - 1.9e-32 111.0 0.0 1.3e-13 50.7 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.4 143392.3_18527001_1 - 2.8e-32 111.0 0.0 6.4e-15 55.4 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.23 143392.3_18527001_1 - 2.9e-25 88.1 0.0 5.2e-09 36.0 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 143392.3_18527001_1 - 3.5e-21 75.3 0.0 7e-07 29.2 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.4 143392.3_18527001_1 - 1.1e-14 54.3 0.0 2.9e-07 30.6 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.10 143392.3_18527001_1 - 0.0011 18.9 0.0 0.0073 16.2 0.0 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain KIAA1430 PF13879.4 143205.2_18523001_3 - 4.6e-14 52.9 2.3 4.6e-14 52.9 2.3 2.6 3 0 0 3 3 3 1 KIAA1430 homologue Sugar_tr PF00083.22 001347749.1_18524001_3 - 1.2e-54 185.8 24.8 1.6e-54 185.4 24.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001347749.1_18524001_3 - 1e-23 83.8 42.4 6.9e-19 67.8 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RhodobacterPufX PF11511.6 001347749.1_18524001_3 - 6.7 6.3 6.9 3.3 7.3 0.9 2.7 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Amidase_2 PF01510.23 141822.3_18523001_3 - 5.1e-15 55.9 0.0 8.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase dsDNA_bind PF01984.18 001043249.2_18524001_3 - 0.2 11.8 0.2 0.2 11.8 0.2 2.3 3 0 0 3 3 3 0 Double-stranded DNA-binding domain Pkinase PF00069.23 001275709.1_18529001_3 - 4.7e-69 232.5 0.0 9e-69 231.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001275709.1_18529001_3 - 1.6e-45 155.3 0.0 2.5e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.26 001275709.1_18529001_3 - 1.1e-16 60.9 0.0 2.5e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.4 001275709.1_18529001_3 - 2.9e-06 26.7 0.0 3.1e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like SH2 PF00017.22 143516.4_18522001_3 - 6.2e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 SH2 domain DUF3460 PF11943.6 143534.3_18525001_1 - 0.18 12.0 0.1 0.36 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Metallophos PF00149.26 143534.3_18525001_2 - 1.8e-25 90.5 1.4 1.8e-25 90.5 1.4 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase ADK PF00406.20 143565.3_18523001_2 - 0.0003 20.8 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.4 143565.3_18523001_2 - 0.073 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_S30 PF04758.12 142665.3_18522001_1 - 8.9e-30 102.6 11.2 1.3e-29 102.1 11.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.21 142665.3_18522001_1 - 0.0042 16.6 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UCH PF00443.27 001276132.1_18529001_2 - 4.8e-30 104.8 0.6 1.8e-26 93.0 0.9 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 001276132.1_18529001_2 - 3.5e-08 33.3 0.2 3.5e-08 33.3 0.2 3.4 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Anoctamin PF04547.10 001275807.1_18528001_3 - 3.7e-149 497.1 17.1 4.9e-149 496.7 17.1 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.3 001275807.1_18528001_3 - 1.5e-68 230.8 0.6 2.2e-68 230.2 0.6 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF3810 PF12725.5 001275807.1_18528001_3 - 0.49 9.6 6.2 1.1 8.4 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) zf-C2H2 PF00096.24 001275489.2_18529001_1 - 1.4e-09 37.7 25.7 0.00049 20.3 1.3 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001275489.2_18529001_1 - 4.1e-06 27.0 33.4 0.041 14.6 0.9 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger Myb_DNA-binding PF00249.29 001275489.2_18529001_1 - 9.5e-06 25.5 0.1 1.8e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_6 PF13912.4 001275489.2_18529001_1 - 0.00019 21.2 22.6 0.00033 20.4 1.3 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger ELM2 PF01448.22 001275489.2_18529001_1 - 0.00026 21.5 0.0 0.00061 20.4 0.0 1.7 1 0 0 1 1 1 1 ELM2 domain zf-met PF12874.5 001275489.2_18529001_1 - 0.0031 17.7 10.1 0.95 9.8 0.6 4.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.5 001275489.2_18529001_1 - 0.24 11.6 10.0 0.69 10.1 0.1 2.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.4 001275489.2_18529001_1 - 0.41 11.1 36.4 0.01 16.1 1.5 6.2 7 0 0 7 7 7 0 Zinc-finger double domain zf-C2H2_jaz PF12171.6 001275489.2_18529001_1 - 0.61 10.3 12.7 3.6 7.9 0.6 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.3 001275489.2_18529001_1 - 7.5 7.0 8.4 0.22 11.9 0.1 2.8 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Surp PF01805.18 142326.3_18526001_1 - 7.2e-45 150.7 4.9 3.9e-22 77.9 0.1 2.8 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.6 142326.3_18526001_1 - 1e-43 149.6 10.6 5.1e-42 144.0 10.6 2.3 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.21 142326.3_18526001_1 - 4.1e-14 51.9 0.0 9.5e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.4 142326.3_18526001_1 - 0.021 15.1 0.0 0.091 13.1 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain Zip PF02535.20 142326.3_18526001_1 - 0.76 8.8 3.2 1.3 8.1 3.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PTPA PF03095.13 142611.1_18524001_1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein Ldh_2 PF02615.12 142611.1_18524001_2 - 1.6e-80 270.7 0.5 1.9e-80 270.4 0.5 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase SURF4 PF02077.13 206480.3_18523001_1 - 3.6e-09 36.5 5.0 8.3e-09 35.3 3.1 2.1 2 1 0 2 2 2 1 SURF4 family MOZART1 PF12554.6 206480.3_18523001_2 - 2.7e-09 36.5 0.1 6.5e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Peptidase_A22B PF04258.11 170244.2_18525001_2 - 2.2e-93 312.8 11.1 2.9e-93 312.4 11.1 1.1 1 0 0 1 1 1 1 Signal peptide peptidase MDM1 PF15501.4 001275421.1_18529001_1 - 3.9e-48 164.8 30.0 9.7e-42 143.7 17.9 4.1 1 1 1 3 3 3 2 Nuclear protein MDM1 Tmemb_9 PF05434.9 001275421.1_18529001_2 - 0.0078 15.9 6.8 0.019 14.6 6.8 1.6 1 0 0 1 1 1 1 TMEM9 DUF4834 PF16118.3 001275421.1_18529001_2 - 0.013 16.3 4.7 0.013 16.3 4.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Zip PF02535.20 001275421.1_18529001_2 - 0.047 12.8 1.1 0.083 12.0 1.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Cadherin_C_2 PF16492.3 001275421.1_18529001_2 - 0.56 10.9 8.4 0.096 13.3 3.4 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Shisa PF13908.4 001275421.1_18529001_2 - 1.7 8.7 15.7 1.5 8.9 6.6 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1510 PF07423.9 001275421.1_18529001_2 - 1.9 7.8 14.5 0.027 13.8 4.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) MAP17 PF15807.3 001275421.1_18529001_2 - 2.5 8.2 8.7 0.042 13.9 0.8 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EPL1 PF10513.7 001275789.1_18527001_1 - 1.6 8.9 10.9 0.92 9.7 3.7 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like EIIBC-GUT_N PF03612.12 001275789.1_18527001_1 - 4 7.0 5.2 9.4 5.8 5.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus 4F5 PF04419.12 001300436.1_18523001_1 - 2.7e-09 37.6 8.5 2.7e-09 37.6 8.5 2.4 2 0 0 2 2 2 1 4F5 protein family 7tm_1 PF00001.19 001275786.2_18529001_3 - 6e-76 255.1 0.0 1.4e-75 253.9 0.0 1.7 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Mito_carr PF00153.25 141877.2_18523001_2 - 2.4e-65 216.4 3.2 1.6e-25 88.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UNC80 PF15778.3 001276094.1_18529001_3 - 3.9e-82 274.3 0.0 7.7e-82 273.3 0.0 1.5 1 0 0 1 1 1 1 Cation channel complex component UNC80 UNC80 PF15778.3 001276095.1_18529001_3 - 3.9e-82 274.3 0.0 7.8e-82 273.3 0.0 1.5 1 0 0 1 1 1 1 Cation channel complex component UNC80 AWPM-19 PF05512.9 079611.2_18523001_1 - 0.58 10.2 2.4 0.26 11.3 0.2 1.4 2 0 0 2 2 2 0 AWPM-19-like family MRJP PF03022.14 079611.2_18523001_3 - 1.3e-107 359.3 0.0 1.6e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein Kelch_6 PF13964.4 079611.2_18523001_3 - 0.059 13.6 0.1 4 7.7 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Piezo_RRas_bdg PF12166.6 001316564.1_18529001_1 - 5.4e-58 197.1 2.3 5.4e-58 197.1 2.3 2.1 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.3 001316564.1_18529001_1 - 1.5e-29 102.9 2.6 4e-29 101.6 2.6 1.6 1 0 0 1 1 1 1 Piezo FLYWCH PF04500.14 001316605.1_18525001_1 - 9.9e-15 54.3 7.2 1.7e-14 53.5 7.2 1.4 1 0 0 1 1 1 1 FLYWCH zinc finger domain MAR_sialic_bdg PF10564.7 001316605.1_18525001_1 - 0.055 13.4 1.9 0.11 12.4 1.9 1.4 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat FLYWCH PF04500.14 001316605.1_18525001_2 - 3.4e-26 91.0 12.6 1.5e-14 53.7 2.1 2.6 2 0 0 2 2 2 2 FLYWCH zinc finger domain RRM_5 PF13893.4 001170318.2_18525001_2 - 1.6e-45 153.7 3.7 1e-31 109.0 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 001170318.2_18525001_2 - 1.2e-26 92.2 0.0 1e-07 31.5 0.0 4.9 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001170318.2_18525001_2 - 2.7e-05 23.8 0.4 3.8 7.3 0.0 4.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif SH3_9 PF14604.4 001276195.1_18528001_3 - 3.3e-44 148.4 2.6 6.9e-15 54.5 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.26 001276195.1_18528001_3 - 1.8e-35 120.2 3.8 6e-12 44.8 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.15 001276195.1_18528001_3 - 1e-32 111.5 1.1 3.3e-12 45.8 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SlyX PF04102.10 001276195.1_18528001_3 - 0.011 16.2 1.5 0.051 14.1 1.5 2.1 1 0 0 1 1 1 0 SlyX Mt_ATP-synt_D PF05873.10 001276195.1_18528001_3 - 0.048 13.4 0.3 0.1 12.3 0.3 1.5 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) IncA PF04156.12 001276195.1_18528001_3 - 0.4 10.3 8.0 0.72 9.5 8.0 1.4 1 0 0 1 1 1 0 IncA protein SH3_9 PF14604.4 001276196.1_18526001_3 - 7.4e-21 73.6 1.6 2.3e-14 52.8 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.15 001276196.1_18526001_3 - 6.5e-17 60.8 1.7 2.4e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.26 001276196.1_18526001_3 - 1.1e-12 47.2 3.4 5.5e-09 35.3 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SlyX PF04102.10 001276196.1_18526001_3 - 0.02 15.3 2.9 0.037 14.5 1.5 2.1 2 0 0 2 2 2 0 SlyX Mt_ATP-synt_D PF05873.10 001276196.1_18526001_3 - 0.033 13.9 0.3 0.075 12.7 0.3 1.5 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) IncA PF04156.12 001276196.1_18526001_3 - 0.29 10.8 8.0 0.5 10.0 8.0 1.4 1 0 0 1 1 1 0 IncA protein Mt_ATP-synt_D PF05873.10 001276198.1_18525001_1 - 0.023 14.4 0.3 0.054 13.2 0.3 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) SlyX PF04102.10 001276198.1_18525001_1 - 0.027 14.9 1.5 0.027 14.9 1.5 2.3 2 0 0 2 2 2 0 SlyX IncA PF04156.12 001276198.1_18525001_1 - 0.2 11.3 8.1 0.35 10.5 8.1 1.4 1 0 0 1 1 1 0 IncA protein RCC1 PF00415.16 001300664.1_18529001_2 - 1.8e-42 143.6 1.3 7.9e-13 48.7 0.1 8.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 001300664.1_18529001_2 - 4.8e-13 48.4 25.7 0.00057 19.5 0.1 7.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Ldl_recept_a PF00057.16 176565.2_18527001_1 - 1.3e-77 255.5 136.2 4.7e-13 49.0 12.9 8.3 7 1 1 8 8 8 7 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.15 176565.2_18527001_1 - 1.3e-35 121.5 5.8 1.7e-11 44.2 0.4 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.4 176565.2_18527001_1 - 6.7e-18 64.5 35.9 7.1e-10 38.9 11.6 5.8 5 1 0 5 5 5 3 Coagulation Factor Xa inhibitory site cEGF PF12662.5 176565.2_18527001_1 - 3.2e-14 52.4 14.1 1.1e-09 37.9 2.8 5.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_CA PF07645.13 176565.2_18527001_1 - 2.7e-09 37.0 22.3 1.1e-07 31.8 5.1 9.9 9 2 3 12 12 12 2 Calcium-binding EGF domain SGL PF08450.10 176565.2_18527001_1 - 0.00074 19.0 4.1 0.5 9.8 0.1 3.3 1 1 2 4 4 4 2 SMP-30/Gluconolaconase/LRE-like region Protocadherin PF08374.9 176565.2_18527001_1 - 0.045 13.6 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Ldl_recept_a PF00057.16 001276041.1_18527001_3 - 2.1e-79 261.3 138.1 3.4e-13 49.4 11.1 8.4 7 1 1 8 8 8 7 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.15 001276041.1_18527001_3 - 1.1e-35 121.7 5.8 1.7e-11 44.3 0.4 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.4 001276041.1_18527001_3 - 5.9e-18 64.7 35.9 6.9e-10 38.9 11.6 6.5 6 1 0 6 6 6 3 Coagulation Factor Xa inhibitory site cEGF PF12662.5 001276041.1_18527001_3 - 3.8e-10 39.4 28.6 1.1e-09 37.9 2.8 6.3 6 0 0 6 6 6 3 Complement Clr-like EGF-like EGF_CA PF07645.13 001276041.1_18527001_3 - 2.5e-09 37.1 22.3 1.1e-07 31.8 5.1 9.9 8 1 2 10 10 10 2 Calcium-binding EGF domain SGL PF08450.10 001276041.1_18527001_3 - 0.00061 19.3 3.9 0.48 9.8 0.3 3.3 1 1 3 4 4 4 2 SMP-30/Gluconolaconase/LRE-like region Protocadherin PF08374.9 001276041.1_18527001_3 - 0.041 13.7 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Protocadherin ATAD4 PF15321.4 001043199.2_18522001_1 - 0.01 17.0 3.9 0.018 16.3 3.9 1.6 1 1 0 1 1 1 0 ATPase family AAA domain containing 4 DUF455 PF04305.12 001043199.2_18522001_1 - 0.017 14.6 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF455) GTP_EFTU PF00009.25 001300539.1_18525001_1 - 1.4e-61 207.3 1.5 3.4e-61 206.0 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.4 001300539.1_18525001_1 - 2.8e-25 88.1 0.0 5.2e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.3 001300539.1_18525001_1 - 9e-09 35.1 0.0 1.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.23 001300539.1_18525001_1 - 1e-05 25.7 0.1 2.6e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001300539.1_18525001_1 - 0.00032 20.6 0.1 0.00066 19.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.3 001300539.1_18525001_1 - 0.014 15.7 0.0 0.33 11.3 0.0 2.8 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain EFG_C PF00679.22 001300539.1_18525001_2 - 5.9e-19 67.8 0.0 1.2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Trypsin PF00089.24 001043294.2_18522001_3 - 4.7e-19 69.0 0.0 5.7e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin Vps5 PF09325.8 001300433.1_18523001_2 - 0.0028 17.1 1.5 0.0028 17.1 1.5 1.5 1 1 0 1 1 1 1 Vps5 C terminal like Prefoldin PF02996.15 001300433.1_18523001_2 - 0.0049 16.6 1.5 0.0049 16.6 1.5 2.1 2 1 1 3 3 3 1 Prefoldin subunit DUF4795 PF16043.3 001300433.1_18523001_2 - 0.012 15.1 9.2 0.027 13.9 9.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) LMBR1 PF04791.14 001300433.1_18523001_2 - 0.052 12.3 2.9 0.073 11.8 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CtIP_N PF10482.7 001300433.1_18523001_2 - 0.065 13.2 5.2 0.23 11.4 0.2 2.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain FliJ PF02050.14 001300433.1_18523001_2 - 0.13 12.4 2.8 0.26 11.4 1.7 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein WEMBL PF05701.9 001300433.1_18523001_2 - 0.15 10.5 4.4 0.21 10.1 4.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF948 PF06103.9 001300433.1_18523001_2 - 0.17 12.0 3.4 0.72 10.0 0.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) P4Ha_N PF08336.9 001300433.1_18523001_2 - 0.2 11.5 3.2 0.24 11.3 0.1 2.4 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CENP-Q PF13094.4 001300433.1_18523001_2 - 0.21 11.6 2.9 0.16 12.0 1.1 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HMMR_N PF15905.3 001300433.1_18523001_2 - 0.21 10.9 8.1 0.32 10.3 8.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Reo_sigmaC PF04582.10 001300433.1_18523001_2 - 0.29 10.3 1.7 0.43 9.8 1.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Phage_GP20 PF06810.9 001300433.1_18523001_2 - 0.59 9.8 6.0 0.89 9.2 4.2 2.2 1 1 0 1 1 1 0 Phage minor structural protein GP20 Laminin_II PF06009.10 001300433.1_18523001_2 - 0.67 9.8 6.3 0.29 11.0 2.1 2.0 2 0 0 2 2 2 0 Laminin Domain II Prefoldin_2 PF01920.18 001300433.1_18523001_2 - 0.93 9.4 9.9 0.65 9.9 6.4 2.4 1 1 1 2 2 2 0 Prefoldin subunit Baculo_PEP_C PF04513.10 001300433.1_18523001_2 - 0.95 9.4 5.5 0.5 10.3 2.5 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.7 001300433.1_18523001_2 - 1.1 9.4 6.8 0.42 10.8 3.7 1.9 2 0 0 2 2 1 0 Uncharacterized conserved protein Laminin_I PF06008.12 001300433.1_18523001_2 - 1.2 8.6 8.8 0.33 10.5 4.1 1.8 1 1 0 2 2 2 0 Laminin Domain I DUF1664 PF07889.10 001300433.1_18523001_2 - 1.5 8.7 5.0 0.54 10.1 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.7 001300433.1_18523001_2 - 2.2 8.5 11.4 2.6 8.3 0.4 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3552 PF12072.6 001300433.1_18523001_2 - 3.3 6.9 8.2 0.13 11.6 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Exo_endo_phos PF03372.21 001275542.1_18524001_3 - 8.6e-15 54.9 0.0 1.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LIM PF00412.20 001170103.2_18527001_2 - 2.5e-42 142.8 51.1 5.1e-13 48.9 4.7 4.5 4 0 0 4 4 4 4 LIM domain VHP PF02209.17 001170103.2_18527001_2 - 2.8e-15 56.0 2.2 1.3e-13 50.6 0.1 2.7 2 0 0 2 2 2 2 Villin headpiece domain Lipocalin_2 PF08212.10 001275681.1_18522001_3 - 0.00036 20.4 0.1 0.00049 20.0 0.1 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.21 001275681.1_18522001_3 - 0.029 14.4 0.2 0.048 13.7 0.2 1.4 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Tet_res_leader PF08050.10 001275886.1_18527001_1 - 0.025 14.3 0.2 0.067 12.9 0.2 1.8 1 0 0 1 1 1 0 Tetracycline resistance leader peptide NifU PF01106.15 001300393.1_18523001_2 - 0.71 9.9 0.0 0.71 9.9 0.0 2.8 3 0 0 3 3 3 0 NifU-like domain adh_short_C2 PF13561.4 169084.2_18522001_3 - 1.8e-62 210.8 0.0 2.1e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 169084.2_18522001_3 - 1.9e-49 167.6 0.0 2.3e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 169084.2_18522001_3 - 3.1e-08 33.6 0.0 4.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Acetyltransf_1 PF00583.23 176441.2_18523001_1 - 0.0031 17.6 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Hydrolase_4 PF12146.6 001170248.2_18524001_2 - 3.5e-13 49.3 0.0 3.6e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.19 001170248.2_18524001_2 - 5.5e-06 25.9 0.0 5.9e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.18 001170248.2_18524001_2 - 7.6e-05 22.3 0.1 0.048 13.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.16 001170248.2_18524001_2 - 0.00012 21.6 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.5 001170248.2_18524001_2 - 0.00034 21.2 0.1 0.063 13.8 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.5 001170248.2_18524001_2 - 0.014 15.0 0.0 0.044 13.4 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF818 PF05677.10 001170248.2_18524001_2 - 0.052 12.4 0.1 0.078 11.8 0.1 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.14 001170248.2_18524001_2 - 0.058 13.1 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase UPF0227 PF05728.10 001170248.2_18524001_2 - 0.06 13.2 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.11 001170248.2_18524001_2 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) EF-hand_1 PF00036.30 176482.2_18522001_2 - 2.9e-08 32.5 0.6 2e-05 23.7 0.2 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.4 176482.2_18522001_2 - 3.8e-08 32.5 1.0 2.7e-05 23.6 0.3 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.4 176482.2_18522001_2 - 3.7e-06 27.2 1.3 2.9e-05 24.3 1.0 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.4 176482.2_18522001_2 - 0.00025 20.6 0.1 0.001 18.7 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.4 176482.2_18522001_2 - 0.00043 19.5 0.5 0.00043 19.5 0.5 2.0 2 0 0 2 2 2 1 EF hand GPHH PF16905.3 176482.2_18522001_2 - 0.028 14.1 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated UPF0154 PF03672.11 176482.2_18522001_2 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) 2OG-FeII_Oxy PF03171.18 176537.2_18523001_1 - 2.6e-16 59.8 0.0 5.8e-16 58.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 176537.2_18523001_1 - 5e-16 59.4 0.0 7.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WW PF00397.24 001202340.2_18525001_2 - 1.1e-12 47.5 9.9 1.4e-08 34.4 4.0 2.7 2 0 0 2 2 2 2 WW domain DUF3585 PF12130.6 176444.2_18529001_2 - 3.2e-23 82.2 15.0 3.2e-23 82.2 15.0 4.0 3 0 0 3 3 1 1 Protein of unknown function (DUF3585) CH PF00307.29 176444.2_18529001_2 - 2.1e-09 37.4 0.0 6.6e-09 35.8 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.20 176444.2_18529001_2 - 8.9e-06 25.7 6.0 2.2e-05 24.4 6.0 1.7 1 0 0 1 1 1 1 LIM domain Pyr_redox_3 PF13738.4 176444.2_18529001_2 - 3.8e-05 23.0 0.0 3.8e-05 23.0 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.12 176444.2_18529001_2 - 5e-05 22.6 0.1 0.00013 21.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 176444.2_18529001_2 - 0.00016 20.4 0.0 0.00046 18.9 0.0 1.8 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.19 176444.2_18529001_2 - 0.00035 19.8 0.5 0.0037 16.5 0.2 2.6 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.22 176444.2_18529001_2 - 0.00042 19.4 0.1 0.00042 19.4 0.1 2.0 2 0 0 2 2 1 1 FAD binding domain FAD_binding_3 PF01494.17 176444.2_18529001_2 - 0.00059 19.1 0.2 0.0015 17.7 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.22 176444.2_18529001_2 - 0.0053 16.3 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.25 176444.2_18529001_2 - 0.0079 16.6 0.1 0.021 15.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 176444.2_18529001_2 - 0.011 15.8 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain CAMSAP_CH PF11971.6 176444.2_18529001_2 - 0.011 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain Lycopene_cycl PF05834.10 176444.2_18529001_2 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MutS_II PF05188.15 176444.2_18529001_2 - 0.63 10.2 3.6 2.3 8.4 3.6 1.9 1 0 0 1 1 1 0 MutS domain II zf-FCS PF06467.12 176444.2_18529001_2 - 0.92 9.4 5.9 1.6 8.7 1.7 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif LMWPc PF01451.19 001032015.2_18522001_2 - 1.2e-39 135.7 0.0 1.5e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase WW PF00397.24 001300400.1_18529001_2 - 2.2e-17 62.6 0.3 4e-08 32.9 0.1 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.28 001300400.1_18529001_2 - 4.7e-07 29.9 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain zf-C3HC4_3 PF13920.4 001144628.3_18522001_2 - 4.8e-10 39.0 6.3 7.3e-10 38.4 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001144628.3_18522001_2 - 1.5e-08 34.3 8.6 2.4e-08 33.6 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001144628.3_18522001_2 - 4.2e-07 29.6 9.3 7.6e-07 28.7 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001144628.3_18522001_2 - 9.9e-07 28.8 9.9 1.8e-06 28.0 9.9 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.4 001144628.3_18522001_2 - 1.3e-06 28.0 7.0 2.2e-06 27.3 7.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 001144628.3_18522001_2 - 3.6e-06 26.7 8.0 6.9e-06 25.8 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001144628.3_18522001_2 - 1.3e-05 25.0 6.0 1.5e-05 24.7 4.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001144628.3_18522001_2 - 2.4e-05 24.3 9.0 4.1e-05 23.5 9.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.4 001144628.3_18522001_2 - 0.00027 20.5 5.5 0.00064 19.3 5.5 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.5 001144628.3_18522001_2 - 0.00053 20.1 5.5 0.00086 19.4 5.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain Rad50_zn_hook PF04423.12 001144628.3_18522001_2 - 0.0033 17.1 0.4 0.0056 16.4 0.4 1.3 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-ANAPC11 PF12861.5 001144628.3_18522001_2 - 0.014 15.3 1.7 0.025 14.5 1.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.3 001144628.3_18522001_2 - 0.051 13.6 4.6 0.086 12.9 4.6 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 PH PF00169.27 001275620.1_18529001_1 - 2.3e-17 63.3 0.1 7.4e-17 61.7 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.4 001275620.1_18529001_1 - 0.0027 17.8 0.1 0.0097 16.0 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.4 001275620.1_18529001_1 - 0.75 10.1 14.6 0.053 13.8 4.5 3.6 2 1 0 2 2 2 0 Pleckstrin homology domain CUB PF00431.18 001300376.1_18525001_1 - 2.5e-38 130.7 0.0 1.5e-13 50.9 0.0 3.4 3 0 0 3 3 3 3 CUB domain KH_1 PF00013.27 001202272.2_18527001_3 - 1.5e-40 136.7 12.0 3.5e-15 55.4 1.4 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.4 001202272.2_18527001_3 - 1.9e-06 27.5 2.1 0.042 13.6 0.0 3.0 3 0 0 3 3 3 2 KH domain KH_2 PF07650.15 001202272.2_18527001_3 - 2.6e-06 27.0 11.6 0.00011 21.8 0.8 2.9 2 1 1 3 3 3 2 KH domain TMEM65 PF10507.7 001202272.2_18527001_3 - 0.18 11.7 0.8 0.53 10.2 0.8 1.8 1 0 0 1 1 1 0 Transmembrane protein 65 KH_5 PF13184.4 001202272.2_18527001_3 - 0.96 9.5 4.8 2.5 8.1 0.2 2.8 3 0 0 3 3 3 0 NusA-like KH domain FLYWCH PF04500.14 001202327.2_18524001_1 - 1e-09 38.2 1.0 1.8e-09 37.4 1.0 1.4 1 0 0 1 1 1 1 FLYWCH zinc finger domain FLYWCH PF04500.14 001202327.2_18524001_3 - 5.4e-15 55.1 0.4 1.1e-14 54.1 0.4 1.6 1 0 0 1 1 1 1 FLYWCH zinc finger domain zf-C2H2 PF00096.24 001275414.2_18529001_2 - 6.1e-21 73.5 53.0 2.5e-05 24.3 3.3 7.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001275414.2_18529001_2 - 5.8e-16 58.0 47.4 1.5e-05 25.1 2.4 8.1 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 001275414.2_18529001_2 - 1.2e-08 35.0 62.5 0.0042 17.7 2.3 7.9 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001275414.2_18529001_2 - 4.8e-05 23.4 18.4 0.019 15.1 8.8 3.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.5 001275414.2_18529001_2 - 0.0012 19.0 1.8 0.0012 19.0 1.8 6.9 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.4 001275414.2_18529001_2 - 0.016 15.0 3.1 9 6.2 0.0 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.3 001275414.2_18529001_2 - 0.61 9.8 26.6 2.2 8.0 0.9 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type Fer4_10 PF13237.4 001275414.2_18529001_2 - 3.4 7.7 8.7 3.9 7.5 0.9 3.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain RA PF00788.21 001275343.1_18529001_1 - 2.7e-41 140.0 0.6 1.3e-21 76.9 0.0 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain DIL PF01843.17 001275343.1_18529001_1 - 7.7e-25 87.1 7.3 7.7e-25 87.1 7.3 2.6 2 1 0 2 2 2 1 DIL domain PDZ PF00595.22 001275343.1_18529001_1 - 1.4e-16 60.4 0.3 4.5e-16 58.8 0.3 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FHA PF00498.24 001275343.1_18529001_1 - 2.5e-08 34.0 0.0 6.5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain PDZ_2 PF13180.4 001275343.1_18529001_1 - 0.00064 19.9 0.1 0.0021 18.2 0.1 1.9 1 0 0 1 1 1 1 PDZ domain Yop-YscD_cpl PF16697.3 001275343.1_18529001_1 - 0.0025 18.0 0.0 0.0095 16.1 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FERM_f0 PF16511.3 001275343.1_18529001_1 - 0.043 14.0 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM E1_UFD PF09358.8 001275343.1_18529001_1 - 0.093 13.3 0.2 4.4 8.0 0.0 3.2 2 0 0 2 2 2 0 Ubiquitin fold domain Pkinase PF00069.23 001144649.2_18525001_1 - 1.9e-50 171.6 0.5 2.5e-50 171.1 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001144649.2_18525001_1 - 4.3e-21 75.2 0.2 8.2e-21 74.3 0.2 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Macoilin PF09726.7 001144649.2_18525001_1 - 0.066 11.6 6.6 0.093 11.1 6.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2062 PF09835.7 001170113.1_18522001_1 - 0.36 10.6 3.4 0.56 9.9 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) KH_1 PF00013.27 001300324.1_18526001_2 - 1.5e-41 139.9 10.7 2.8e-15 55.8 1.4 3.9 4 0 0 4 4 4 3 KH domain KH_2 PF07650.15 001300324.1_18526001_2 - 1.7e-07 30.8 10.8 8.9e-05 22.1 0.8 2.9 2 1 0 3 3 3 2 KH domain KH_4 PF13083.4 001300324.1_18526001_2 - 2.6e-06 27.1 3.7 0.028 14.2 0.1 3.2 3 0 0 3 3 3 2 KH domain KH_5 PF13184.4 001300324.1_18526001_2 - 0.32 11.0 4.1 2 8.4 0.2 2.9 3 0 0 3 3 3 0 NusA-like KH domain TMEM65 PF10507.7 001300324.1_18526001_2 - 4.9 7.0 6.3 0.42 10.5 0.8 2.2 2 0 0 2 2 2 0 Transmembrane protein 65 zn-ribbon_14 PF16503.3 001276063.1_18521001_1 - 0.16 11.3 0.0 0.16 11.3 0.0 2.3 2 1 0 2 2 2 0 Zinc-ribbon DUF4819 PF16090.3 001275826.1_18529001_2 - 2.6e-24 84.9 1.2 7e-24 83.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4819) HMG_box PF00505.17 001275826.1_18529001_2 - 3.8e-16 59.1 4.4 1e-15 57.8 4.4 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001275826.1_18529001_2 - 7.7e-07 29.5 3.0 7.7e-07 29.5 3.0 2.6 3 0 0 3 3 3 1 HMG-box domain bZIP_Maf PF03131.15 001275935.1_18529001_2 - 1.2e-19 70.4 3.4 1.2e-19 70.4 3.4 3.8 4 0 0 4 4 4 1 bZIP Maf transcription factor bZIP_1 PF00170.19 001275935.1_18529001_2 - 1.7e-06 27.9 6.7 1.7e-06 27.9 6.7 2.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.13 001275935.1_18529001_2 - 0.0019 18.1 5.7 0.0019 18.1 5.7 2.7 4 0 0 4 4 4 1 Basic region leucine zipper RNA_pol_Rpb4 PF03874.14 001014634.3_18525001_1 - 1.2e-20 74.0 1.4 1.7e-20 73.4 1.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 AAA_5 PF07728.12 001014634.3_18525001_1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SWIRM PF04433.15 001014634.3_18525001_3 - 1.5e-08 34.7 0.1 6.7e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.4 001014634.3_18525001_3 - 1.6e-05 25.0 0.3 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.29 001014634.3_18525001_3 - 0.0001 22.2 0.3 0.00028 20.8 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.8 001014634.3_18525001_3 - 0.02 14.8 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 SLIDE ZZ PF00569.15 001014634.3_18525001_3 - 1.4 8.7 7.7 4.2 7.1 7.7 1.9 1 0 0 1 1 1 0 Zinc finger, ZZ type RNA_pol_Rpb4 PF03874.14 001170174.2_18525001_3 - 1.4e-20 73.7 1.2 1.4e-20 73.7 1.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb4 SWIRM PF04433.15 001170174.2_18525001_3 - 6.8e-09 35.8 1.3 5.9e-08 32.8 0.0 3.0 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.4 001170174.2_18525001_3 - 8.4e-06 25.8 0.3 0.0001 22.4 0.1 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.29 001170174.2_18525001_3 - 5.7e-05 23.1 0.3 0.00025 21.0 0.3 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.8 001170174.2_18525001_3 - 0.016 15.1 0.0 0.051 13.5 0.0 1.8 1 0 0 1 1 1 0 SLIDE ZZ PF00569.15 001170174.2_18525001_3 - 1.9 8.3 7.7 3.7 7.3 7.7 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-BED PF02892.13 001300524.1_18524001_2 - 0.055 13.4 1.4 0.18 11.8 1.4 1.9 1 0 0 1 1 1 0 BED zinc finger FLYWCH PF04500.14 001300522.1_18525001_1 - 6.8e-16 58.0 1.9 6.8e-16 58.0 1.9 2.0 3 0 0 3 3 3 1 FLYWCH zinc finger domain PMP22_Claudin PF00822.18 001300542.1_18524001_2 - 4.4e-12 46.1 3.8 7.3e-12 45.3 3.8 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001300542.1_18524001_2 - 0.0012 18.5 14.2 0.0089 15.7 13.8 2.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.7 001300542.1_18524001_2 - 0.0028 17.8 4.7 0.0054 16.8 4.7 1.5 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.9 001300542.1_18524001_2 - 0.049 13.4 5.7 0.11 12.3 5.7 1.5 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Comm PF15957.3 001300542.1_18524001_2 - 0.058 13.6 1.1 0.45 10.7 0.3 2.5 2 0 0 2 2 2 0 Commissureless Lung_7-TM_R PF06814.11 001300542.1_18524001_2 - 0.15 11.1 3.2 0.27 10.3 3.2 1.3 1 0 0 1 1 1 0 Lung seven transmembrane receptor DUF4407 PF14362.4 001300542.1_18524001_2 - 7.5 5.7 7.6 0.62 9.2 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-AN1 PF01428.14 001300318.1_18526001_2 - 1.7e-09 37.6 7.8 3.4e-09 36.6 7.8 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger TIL PF01826.15 001300654.1_18521001_2 - 3.7e-08 33.4 16.8 5.4e-08 32.8 16.8 1.2 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain rve PF00665.24 133317.1_18521120_2 - 3.5e-12 46.5 0.1 1.7e-11 44.2 0.1 1.9 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.4 133317.1_18521120_2 - 0.00036 20.1 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Transglut_core PF01841.17 125059.1_18521120_2 - 0.027 14.8 0.1 0.033 14.5 0.1 1.2 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF229 PF02995.15 125059.1_18521120_2 - 0.033 12.7 0.0 0.038 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1265 PF06887.12 125068.1_18522120_2 - 0.11 12.3 0.3 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) Dimer_Tnp_hAT PF05699.12 125070.1_18523120_1 - 2.8e-06 26.9 0.5 5.7e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HNH_5 PF14279.4 073982.1_18521120_2 - 0.0032 17.1 0.9 0.0044 16.7 0.9 1.3 1 0 0 1 1 1 1 HNH endonuclease Corona_nucleoca PF00937.16 133330.1_18525120_2 - 0.6 8.9 3.5 0.89 8.4 3.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2806 PF10987.6 133332.1_18523120_2 - 0.13 12.0 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) Antimicrobial19 PF08225.9 125080.1_18522120_1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Pseudin antimicrobial peptide DUF4806 PF16064.3 037755.1_18522120_3 - 0.0021 18.2 0.1 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4806) DUF4716 PF15837.3 125094.1_18522120_3 - 0.092 12.7 1.2 0.2 11.6 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4716) FeoB_N PF02421.16 125105.1_18521120_3 - 0.006 16.0 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Nucleo_P87 PF07267.9 125106.1_18523120_2 - 0.21 10.3 5.1 0.37 9.5 5.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleo_P87 PF07267.9 125107.1_18523120_3 - 0.066 11.9 3.0 0.091 11.5 3.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CAP_N PF01213.17 125108.1_18529120_1 - 0.38 10.1 4.0 0.64 9.3 4.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FHA PF00498.24 133366.1_18521120_3 - 0.065 13.5 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 FHA domain UreE_N PF02814.13 073990.1_18524120_2 - 0.24 10.9 2.1 0.71 9.4 1.6 2.0 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain OAD_gamma PF04277.11 048359.2_18522120_3 - 0.41 11.1 4.7 0.32 11.5 2.7 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PMT_4TMC PF16192.3 125131.2_18524120_1 - 0.012 15.1 1.2 1 8.8 0.9 2.2 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase PmrD PF11183.6 133374.1_18522120_2 - 0.091 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Aerolysin PF01117.18 073999.1_18522120_1 - 0.073 12.1 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Aerolysin toxin DSX_dimer PF08828.8 073999.1_18522120_3 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Doublesex dimerisation domain zf-C3Hc3H PF13891.4 125150.1_18521120_2 - 0.016 15.4 0.1 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 Potential DNA-binding domain Rsm1 PF08600.8 133387.1_18522120_1 - 0.025 14.6 0.9 0.044 13.8 0.9 1.3 1 0 0 1 1 1 0 Rsm1-like FAM27 PF15832.3 074007.1_18522120_1 - 0.024 15.0 0.4 0.048 14.1 0.4 1.5 1 0 0 1 1 1 0 FAM27 D and E protein family NESP55 PF06390.10 125162.1_18524120_1 - 2.7 7.4 5.2 4.3 6.7 5.2 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF3915 PF13054.4 133398.1_18521120_1 - 0.25 11.2 6.0 0.55 10.1 6.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 133398.1_18521120_2 - 0.0079 14.4 0.4 0.0089 14.3 0.4 1.1 1 0 0 1 1 1 1 Atrophin-1 family Bac_export_2 PF01312.17 133398.1_18521120_2 - 0.021 13.9 0.0 0.023 13.8 0.0 1.0 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Phage_int_SAM_3 PF14659.4 125163.1_18522120_3 - 0.052 13.7 0.8 0.094 12.9 0.8 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF4802 PF16060.3 125166.1_18526120_2 - 2.3 8.3 6.3 1e+02 3.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4802) DIM PF08194.10 125171.1_18521120_1 - 0.008 16.2 1.5 0.015 15.4 1.5 1.4 1 0 0 1 1 1 1 DIM protein PT PF04886.10 125177.1_18521120_1 - 0.021 14.3 7.3 0.051 13.0 7.3 1.7 1 0 0 1 1 1 0 PT repeat PT PF04886.10 125177.1_18521120_3 - 5.4e-05 22.5 2.0 5.4e-05 22.5 2.0 1.8 2 0 0 2 2 2 1 PT repeat DNA_gyraseA_C PF03989.11 125181.1_18521120_2 - 0.32 10.4 0.7 4.8 6.6 0.2 2.2 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller CAAD PF14159.4 125181.1_18521120_3 - 1.9 8.2 5.2 2.6 7.8 4.5 1.6 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3797 PF12677.5 125182.1_18521120_1 - 0.0051 16.5 0.2 0.0075 16.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3797) Glyco_transf_36 PF06165.9 125182.1_18521120_1 - 0.054 12.8 0.1 0.066 12.5 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 36 BRD4_CDT PF17105.3 125183.1_18523120_1 - 0.19 11.2 3.2 0.19 11.2 1.3 1.9 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 LacI PF00356.19 133407.1_18529120_3 - 0.16 11.7 1.0 3 7.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family APC_r PF05923.10 002037.3_18525120_3 - 1.9 8.2 3.7 0.61 9.8 0.1 2.1 2 0 0 2 2 2 0 APC repeat APC_r PF05923.10 125190.1_18524120_1 - 2 8.1 3.7 0.52 10.0 0.1 1.9 2 0 0 2 2 2 0 APC repeat YadA_anchor PF03895.13 133415.1_18524120_1 - 0.033 14.4 0.3 0.033 14.4 0.3 1.9 2 0 0 2 2 2 0 YadA-like C-terminal region TIL PF01826.15 133421.1_18521120_3 - 1.3e-05 25.2 12.6 1.7e-05 24.8 12.6 1.2 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain TIL PF01826.15 133422.1_18521120_1 - 1.4e-05 25.1 12.6 1.8e-05 24.8 12.6 1.1 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain Deltaretro_Tax PF05599.9 037763.2_18522120_3 - 0.021 15.2 0.7 0.86 10.0 0.4 2.2 2 0 0 2 2 2 0 Deltaretrovirus Tax protein MCM_bind PF09739.7 125218.1_18522120_1 - 0.11 10.8 0.1 0.15 10.3 0.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF1435 PF07256.10 125218.1_18522120_2 - 0.052 13.5 0.2 0.088 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) DUF1435 PF07256.10 125219.1_18522120_1 - 0.052 13.5 0.3 0.087 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) MCM_bind PF09739.7 125219.1_18522120_3 - 0.11 10.8 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF1435 PF07256.10 125220.1_18522120_2 - 0.051 13.6 0.3 0.086 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) Cylicin_N PF15241.4 074039.1_18523120_3 - 0.067 13.3 0.5 0.067 13.3 0.5 2.1 2 0 0 2 2 2 0 Cylicin N-terminus Rhodanese PF00581.18 074056.1_18522120_3 - 4e-14 52.9 0.0 5.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.18 125240.1_18522120_3 - 3.6e-14 53.0 0.0 5.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain TAL_effector PF03377.11 074058.1_18521120_3 - 0.035 13.9 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 TAL effector repeat zf-Paramyx-P PF13008.5 074058.1_18521120_3 - 0.049 13.0 2.5 0.049 13.0 2.5 1.9 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein DUF3439 PF11921.6 133444.1_18522120_2 - 0.93 9.3 6.6 1.4 8.7 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Spt20 PF12090.6 133444.1_18522120_3 - 2.3 7.6 10.3 3 7.3 10.3 1.1 1 0 0 1 1 1 0 Spt20 family IMUP PF15761.3 048491.1_18522120_3 - 0.3 11.7 8.3 0.42 11.2 8.3 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.7 048491.1_18522120_3 - 0.61 9.5 13.7 0.77 9.2 13.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Surface_antigen PF11054.6 048496.1_18522120_2 - 0.027 14.0 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen BTP PF05232.10 074062.1_18522120_2 - 0.18 11.7 1.6 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Chlorhexidine efflux transporter Cwf_Cwc_15 PF04889.10 125269.1_18522120_1 - 0.13 11.8 1.1 0.17 11.4 1.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mgr1 PF08602.8 133465.1_18521120_2 - 0.028 13.1 0.4 0.035 12.8 0.4 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit F-112 PF09645.8 133468.1_18522120_3 - 0.62 10.3 7.0 1.1 9.5 7.0 1.3 1 0 0 1 1 1 0 F-112 protein Cas9-BH PF16593.3 133476.1_18521120_3 - 3.7 7.2 11.1 6.6 6.4 11.1 1.4 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 Peptidase_U32 PF01136.17 048512.1_18522120_3 - 0.16 10.9 0.5 0.22 10.5 0.5 1.1 1 0 0 1 1 1 0 Peptidase family U32 Calpain_III PF01067.20 133485.1_18522120_1 - 0.026 14.7 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 Calpain large subunit, domain III GxGYxYP_N PF16216.3 133497.1_18522120_3 - 0.14 12.1 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal 2C_adapt PF08793.8 048526.1_18521120_2 - 0.14 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 2-cysteine adaptor domain Maf1 PF09174.8 001015167.3_18523001_1 - 1.1e-60 204.1 0.2 1.6e-60 203.6 0.2 1.2 1 0 0 1 1 1 1 Maf1 regulator DUF21 PF01595.18 001110921.4_18528001_2 - 3.5e-37 127.7 0.2 7.3e-37 126.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.26 001110921.4_18528001_2 - 3.3e-05 24.1 0.1 0.3 11.4 0.1 2.8 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.27 001110921.4_18528001_2 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Nipped-B_C PF12830.5 001042986.3_18529001_3 - 2.3e-59 200.4 0.5 2.3e-59 200.4 0.5 3.5 4 1 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.5 001042986.3_18529001_3 - 3.9e-08 33.2 0.8 7.3e-07 29.1 0.2 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.20 001042986.3_18529001_3 - 0.0015 18.5 3.4 16 5.9 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.4 001042986.3_18529001_3 - 0.045 14.1 0.1 12 6.4 0.0 3.9 3 1 1 4 4 4 0 HEAT-like repeat FAT PF02259.21 001316406.1_18529001_1 - 2.6e-65 220.8 9.7 2.6e-65 220.8 9.7 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.25 001316406.1_18529001_1 - 1.4e-15 57.6 2.3 2.7e-15 56.7 0.6 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.18 001316406.1_18529001_1 - 2.4e-07 30.3 0.1 3.8e-06 26.5 0.1 2.7 2 0 0 2 2 2 1 FATC domain RIX1 PF08167.10 001316406.1_18529001_1 - 0.019 14.6 1.0 0.58 9.7 0.9 3.8 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis GatB_Yqey PF02637.16 001316406.1_18529001_1 - 0.043 13.6 0.5 0.24 11.1 0.1 2.6 3 0 0 3 3 3 0 GatB domain DUF3385 PF11865.6 001316406.1_18529001_1 - 0.079 12.7 10.9 18 5.0 0.2 6.3 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) U3snoRNP10 PF12397.6 001316406.1_18529001_1 - 6.8 7.0 19.3 0.077 13.3 0.1 5.4 6 0 0 6 6 6 0 U3 small nucleolar RNA-associated protein 10 PAW PF04721.15 136348.3_18525001_2 - 3.3e-60 203.2 1.9 3.3e-60 203.2 1.9 1.9 2 0 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.8 136348.3_18525001_2 - 2.3e-19 69.0 0.1 5.3e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.17 136348.3_18525001_2 - 1.7e-11 44.4 0.2 4.6e-11 43.0 0.2 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.13 136348.3_18525001_2 - 5.2e-11 42.3 0.8 1.1e-10 41.2 0.8 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PAW PF04721.15 165454.3_18526001_2 - 4.9e-60 202.6 1.9 4.9e-60 202.6 1.9 1.8 2 0 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.8 165454.3_18526001_2 - 3.3e-19 68.5 0.1 7.2e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.17 165454.3_18526001_2 - 2.8e-11 43.7 0.2 6.6e-11 42.5 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.13 165454.3_18526001_2 - 7.5e-11 41.8 0.8 1.5e-10 40.8 0.8 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain CAP_GLY PF01302.23 136353.2_18525001_2 - 2e-18 66.0 1.7 3.1e-18 65.4 1.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.5 136353.2_18525001_2 - 1.4e-05 25.2 23.3 0.026 14.8 0.9 5.3 2 2 4 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 136353.2_18525001_2 - 0.0022 17.6 16.9 0.013 15.1 0.6 4.4 3 1 1 4 4 4 2 Leucine rich repeat Ubiquitin_2 PF14560.4 136353.2_18525001_2 - 0.0047 17.2 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_9 PF14580.4 136353.2_18525001_2 - 0.17 11.2 5.3 7.4 5.9 0.2 3.3 1 1 2 3 3 3 0 Leucine-rich repeat zf-H2C2_2 PF13465.4 136367.3_18524001_1 - 2.4e-23 81.4 42.4 4.3e-06 26.8 2.6 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.24 136367.3_18524001_1 - 3e-21 74.5 49.5 0.00074 19.7 1.4 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 136367.3_18524001_1 - 6.3e-20 70.0 54.5 0.00033 21.1 1.3 7.7 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.4 136367.3_18524001_1 - 4.8e-09 35.8 40.2 5.3e-05 22.9 0.1 7.7 7 1 0 7 7 7 4 C2H2-type zinc finger zf-AD PF07776.13 136367.3_18524001_1 - 1.2e-08 35.0 3.4 1.2e-08 35.0 3.4 3.2 4 0 0 4 4 3 1 Zinc-finger associated domain (zf-AD) zf-C2H2_jaz PF12171.6 136367.3_18524001_1 - 5.6e-08 32.8 31.6 0.036 14.2 1.8 6.7 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 136367.3_18524001_1 - 8.9e-05 22.6 44.3 0.43 10.9 0.4 7.3 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.3 136367.3_18524001_1 - 0.00033 20.7 16.4 0.012 15.8 3.1 2.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.3 136367.3_18524001_1 - 0.008 15.8 1.8 0.008 15.8 1.8 5.4 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-Di19 PF05605.10 136367.3_18524001_1 - 0.041 14.0 31.7 0.6 10.3 0.7 5.5 2 1 3 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding PDCD2_C PF04194.11 136367.3_18524001_1 - 3.7 7.5 6.7 17 5.4 6.7 2.3 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain CpXC PF14353.4 136367.3_18524001_1 - 6.3 6.7 16.7 1.2 9.0 1.7 4.8 1 1 3 4 4 4 0 CpXC protein zf-C2H2_2 PF12756.5 136367.3_18524001_1 - 7.7 6.8 28.4 13 6.1 0.9 5.3 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) Tetraspannin PF00335.18 165502.2_18523001_3 - 1.6e-45 155.4 15.3 2e-45 155.1 15.3 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF373 PF04123.11 165502.2_18523001_3 - 0.0077 15.6 3.9 0.011 15.1 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF373) TMEM171 PF15471.4 165502.2_18523001_3 - 0.16 10.8 1.8 0.29 9.9 1.8 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 TctB PF07331.9 165502.2_18523001_3 - 2.6 8.2 9.1 25 5.0 6.4 2.4 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Reticulon PF02453.15 165502.2_18523001_3 - 3.1 7.6 9.2 2.1 8.1 0.7 2.2 1 1 1 2 2 2 0 Reticulon Cyt-b5 PF00173.26 136450.4_18522001_1 - 1.1e-24 86.2 0.0 1.6e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CARMIL_C PF16000.3 136472.6_18529001_2 - 1.2e-77 261.4 0.1 1.2e-77 261.4 0.1 2.2 2 0 0 2 2 2 1 CARMIL C-terminus LRR_6 PF13516.4 136472.6_18529001_2 - 2.3e-14 52.0 26.7 0.012 15.5 0.0 10.9 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.5 136472.6_18529001_2 - 1.5e-07 31.4 29.0 0.017 15.4 3.8 7.4 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 136472.6_18529001_2 - 2.2e-07 30.2 13.2 12 6.7 0.2 8.9 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_8 PF13855.4 136472.6_18529001_2 - 0.013 15.1 25.6 1.9 8.2 0.3 6.8 5 1 1 6 6 6 0 Leucine rich repeat DUF4778 PF16008.3 001103743.2_18524001_3 - 3.4e-10 40.3 0.2 1.6e-09 38.2 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4778) Methyltransf_32 PF13679.4 165576.4_18524001_1 - 2e-35 122.0 0.0 3.1e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 165576.4_18524001_1 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ACC_central PF08326.10 136498.3_18529001_1 - 9.9e-266 883.4 9.5 1.4e-265 882.8 9.5 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.20 136498.3_18529001_1 - 8e-162 539.2 0.0 1e-161 538.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.15 136498.3_18529001_1 - 2.8e-52 177.1 0.0 6.5e-52 176.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.20 136498.3_18529001_1 - 2.9e-32 111.3 0.0 8.6e-32 109.8 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.17 136498.3_18529001_1 - 9.4e-21 73.8 0.0 5.1e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.20 136498.3_18529001_1 - 1.7e-15 56.4 0.0 5.1e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.4 136498.3_18529001_1 - 7.3e-06 24.8 0.0 0.0032 16.1 0.0 3.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.11 136498.3_18529001_1 - 0.00091 18.7 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.20 136498.3_18529001_1 - 0.037 13.5 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain MetallophosN PF16371.3 136498.3_18529001_1 - 0.12 12.5 0.0 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase ACC_central PF08326.10 165581.3_18529001_1 - 9.4e-266 883.4 9.5 1.4e-265 882.9 9.5 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.20 165581.3_18529001_1 - 7.7e-162 539.3 0.0 1e-161 538.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.15 165581.3_18529001_1 - 2.8e-52 177.2 0.0 6.3e-52 176.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.20 165581.3_18529001_1 - 2.8e-32 111.4 0.0 8.4e-32 109.9 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.17 165581.3_18529001_1 - 9e-21 73.9 0.0 5e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.20 165581.3_18529001_1 - 1.7e-15 56.5 0.0 5e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.4 165581.3_18529001_1 - 6.7e-06 24.9 0.0 0.0031 16.1 0.0 3.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.11 165581.3_18529001_1 - 0.00088 18.7 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.20 165581.3_18529001_1 - 0.035 13.5 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain MetallophosN PF16371.3 165581.3_18529001_1 - 0.12 12.6 0.0 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase zf-SNAP50_C PF12251.6 136513.4_18524001_3 - 5.3e-56 189.3 0.1 1e-55 188.4 0.1 1.5 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal TFIIIC_sub6 PF10419.7 136513.4_18524001_3 - 4.2e-12 45.5 0.0 9.5e-12 44.4 0.0 1.7 1 0 0 1 1 1 1 TFIIIC subunit NIF PF03031.16 136560.2_18523001_2 - 3.2e-49 166.6 0.1 4.6e-49 166.0 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Trypsin PF00089.24 001103766.3_18524001_1 - 5.7e-64 215.8 0.1 7.8e-64 215.4 0.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001103766.3_18524001_1 - 1.5e-06 29.0 0.0 2.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.13 001103766.3_18524001_1 - 2.7e-06 27.0 0.0 0.026 13.9 0.0 2.8 2 1 1 3 3 3 2 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.9 001103766.3_18524001_1 - 0.0027 18.0 0.1 0.0089 16.3 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) BESS PF02944.18 001103766.3_18524001_2 - 0.2 11.4 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 BESS motif NAD_kinase PF01513.19 176108.2_18524001_3 - 2.5e-10 39.9 0.0 4.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase PAP2 PF01569.19 080252.4_18524001_3 - 6e-26 90.7 3.1 6e-26 90.7 3.1 2.2 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.4 080252.4_18524001_3 - 0.00036 20.1 0.9 0.0007 19.2 0.9 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF4131 PF13567.4 080252.4_18524001_3 - 0.093 12.2 1.6 0.25 10.8 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PID PF00640.21 001259297.2_18526001_2 - 1.1e-22 80.4 0.1 2.2e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.11 001259297.2_18526001_2 - 0.00084 19.4 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.4 001259297.2_18526001_2 - 0.046 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Plasmid_RAQPRD PF09686.8 001259297.2_18526001_2 - 0.055 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) BLOC1S3 PF15753.3 001259297.2_18526001_2 - 0.065 13.2 0.6 0.13 12.2 0.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 TMEM173 PF15009.4 136681.5_18524001_1 - 2.3e-90 302.5 0.1 2.8e-90 302.3 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 173 zf-DHHC PF01529.18 165728.4_18525001_2 - 3.5e-36 124.1 15.4 3.5e-36 124.1 15.4 3.1 3 0 0 3 3 3 1 DHHC palmitoyltransferase Spt4 PF06093.11 165728.4_18525001_2 - 1.6 8.8 7.1 3 7.9 7.1 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger COX7C PF02935.14 144140.3_18521001_3 - 3.5e-16 59.0 0.2 5.5e-16 58.4 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc PigN PF04987.12 136705.3_18527001_2 - 1.5e-86 291.0 46.2 3.8e-86 289.6 46.2 1.7 1 1 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.20 136705.3_18527001_2 - 6.5e-12 45.6 0.0 4.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase RNA_pol_I_A49 PF06870.10 136705.3_18527001_2 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Sulfatase PF00884.21 136705.3_18527001_2 - 0.16 11.2 0.1 1 8.6 0.1 2.0 1 1 1 2 2 2 0 Sulfatase BK_channel_a PF03493.16 001103788.3_18529001_2 - 8.8e-29 99.5 0.0 2.8e-28 97.9 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.14 001103788.3_18529001_2 - 8.2e-09 35.2 2.9 8.2e-09 35.2 2.9 1.9 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.29 001103788.3_18529001_2 - 0.062 12.4 7.6 0.13 11.3 7.6 1.5 1 0 0 1 1 1 0 Ion transport protein CENP-B_dimeris PF09026.8 001103788.3_18529001_2 - 0.2 11.9 0.5 2.5 8.4 0.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BTB PF00651.29 170619.3_18526001_1 - 2.6e-25 88.7 0.4 4.7e-25 87.8 0.4 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.4 170619.3_18526001_1 - 4.3e-05 23.8 7.5 0.013 16.1 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.4 170619.3_18526001_1 - 6.9e-05 22.4 0.6 0.00018 21.1 0.6 1.8 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.24 170619.3_18526001_1 - 0.0011 19.1 8.0 0.0034 17.6 0.4 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF1079 PF06435.9 170619.3_18526001_1 - 0.047 13.8 4.0 0.46 10.6 0.8 3.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) zf-Di19 PF05605.10 170619.3_18526001_1 - 0.12 12.5 4.7 0.79 9.9 4.5 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.5 170619.3_18526001_1 - 2.8 7.8 7.1 59 3.6 7.1 2.5 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cadherin PF00028.15 165794.4_18529001_1 - 2.3e-170 553.5 18.3 7.9e-24 83.8 0.1 10.6 10 0 0 10 10 10 10 Cadherin domain Laminin_G_2 PF02210.22 165794.4_18529001_1 - 9.2e-53 178.0 0.0 2.1e-31 109.0 0.0 2.9 2 0 0 2 2 2 2 Laminin G domain 7tm_2 PF00002.22 165794.4_18529001_1 - 8.4e-32 110.3 16.9 1.4e-31 109.6 16.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_1 PF00054.21 165794.4_18529001_1 - 4.5e-31 107.7 0.0 2.2e-23 82.8 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain GAIN PF16489.3 165794.4_18529001_1 - 1.2e-20 73.8 0.0 2.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain EGF PF00008.25 165794.4_18529001_1 - 4.8e-11 42.6 29.0 2.8e-08 33.8 10.6 8.1 9 0 0 9 9 7 3 EGF-like domain Cadherin_2 PF08266.10 165794.4_18529001_1 - 2e-10 40.2 0.1 3.2 7.5 0.0 7.7 8 0 0 8 8 8 3 Cadherin-like Laminin_EGF PF00053.22 165794.4_18529001_1 - 1.2e-07 31.6 10.9 1.2e-07 31.6 10.9 7.8 6 1 0 6 6 5 2 Laminin EGF domain GPS PF01825.19 165794.4_18529001_1 - 9.5e-06 26.0 1.3 9.5e-06 26.0 1.3 3.0 3 0 0 3 3 1 1 GPCR proteolysis site, GPS, motif Laminin_G_3 PF13385.4 165794.4_18529001_1 - 0.00021 21.4 0.8 1.8 8.6 0.0 3.7 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Dicty_CAR PF05462.9 165794.4_18529001_1 - 0.00061 18.9 3.2 0.001 18.1 3.2 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor hEGF PF12661.5 165794.4_18529001_1 - 0.0016 18.9 25.6 0.0025 18.3 7.7 6.9 6 0 0 6 6 6 3 Human growth factor-like EGF Ank_2 PF12796.5 136770.2_18527001_2 - 3.2e-30 104.4 1.6 8.4e-11 42.2 0.7 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 136770.2_18527001_2 - 2e-23 82.3 5.1 1.9e-07 31.4 0.5 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.28 136770.2_18527001_2 - 1.9e-17 62.7 6.2 0.0011 19.2 0.2 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.4 136770.2_18527001_2 - 5.8e-17 59.9 0.9 0.024 15.0 0.0 6.6 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.4 136770.2_18527001_2 - 2.7e-15 56.1 7.0 5e-07 29.8 0.7 5.3 3 1 3 6 6 6 4 Ankyrin repeats (many copies) LPP PF04728.11 136770.2_18527001_2 - 0.051 13.8 1.5 0.29 11.4 1.5 2.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Neur_chan_LBD PF02931.21 136775.3_18526001_1 - 1.8e-30 105.9 0.3 3.4e-30 105.0 0.3 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 136775.3_18526001_1 - 1.9e-17 64.0 12.0 8e-16 58.7 4.8 2.3 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Pax2_C PF12403.6 165808.2_18523001_3 - 0.31 11.0 3.5 0.18 11.8 1.1 1.8 2 0 0 2 2 2 0 Paired-box protein 2 C terminal Trypsin PF00089.24 136830.7_18522001_2 - 4.2e-53 180.3 0.1 4.9e-53 180.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.13 136830.7_18522001_2 - 0.041 13.3 0.0 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 PHD PF00628.27 078977.5_18529001_2 - 2e-21 75.5 19.2 2.9e-11 42.9 8.2 2.5 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.23 078977.5_18529001_2 - 7.9e-21 73.8 0.0 1.9e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain WSD PF15613.4 078977.5_18529001_2 - 2.8e-10 40.5 2.2 5.1e-06 26.8 0.1 4.9 4 1 0 4 4 4 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.15 078977.5_18529001_2 - 1.5e-07 31.5 3.4 3.3e-07 30.4 3.4 1.6 1 0 0 1 1 1 1 DDT domain MBD PF01429.17 078977.5_18529001_2 - 2.3e-07 30.3 0.0 4.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain WHIM1 PF15612.4 078977.5_18529001_2 - 4.2e-05 22.9 0.0 0.00012 21.5 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.4 078977.5_18529001_2 - 6.7e-05 22.2 12.7 0.0031 16.9 3.2 2.4 2 0 0 2 2 2 2 PHD-finger Zf_RING PF16744.3 078977.5_18529001_2 - 0.9 9.6 10.0 8.5 6.4 0.7 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger Prok-RING_1 PF14446.4 078977.5_18529001_2 - 1 9.2 12.9 3.2 7.6 1.9 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.20 078977.5_18529001_2 - 2.6 7.9 11.5 1.1 9.1 3.0 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lig_chan PF00060.24 136853.1_18524001_1 - 0.035 13.8 0.0 0.096 12.4 0.0 1.8 1 1 0 1 1 1 0 Ligand-gated ion channel AAA_5 PF07728.12 001103809.3_18529001_2 - 5.3e-97 321.1 0.0 1.7e-22 79.8 0.0 9.1 7 1 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA PF00004.27 001103809.3_18529001_2 - 1.7e-25 89.8 0.3 0.0001 22.6 0.0 7.1 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.9 001103809.3_18529001_2 - 7.2e-22 77.5 0.0 1.7e-09 37.5 0.0 6.1 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 001103809.3_18529001_2 - 4.7e-20 72.5 9.9 0.0094 16.2 0.0 8.7 7 2 0 7 7 6 5 AAA ATPase domain AAA_18 PF13238.4 001103809.3_18529001_2 - 1.6e-19 70.6 0.2 0.0061 16.9 0.0 7.9 6 0 0 6 6 6 4 AAA domain AAA_22 PF13401.4 001103809.3_18529001_2 - 2.3e-17 63.4 0.3 0.034 14.3 0.0 7.8 6 0 0 6 6 6 4 AAA domain TsaE PF02367.15 001103809.3_18529001_2 - 7.3e-16 58.2 0.2 0.09 12.6 0.0 6.6 6 0 0 6 6 6 5 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.4 001103809.3_18529001_2 - 3.2e-14 52.9 0.0 0.055 13.4 0.0 6.6 5 0 0 5 5 5 3 AAA domain DUF258 PF03193.14 001103809.3_18529001_2 - 5.6e-12 45.8 3.0 0.99 9.1 0.0 6.6 6 0 0 6 6 6 3 Protein of unknown function, DUF258 Mg_chelatase PF01078.19 001103809.3_18529001_2 - 2e-11 43.5 0.1 3 7.0 0.0 8.6 9 1 0 9 9 8 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.25 001103809.3_18529001_2 - 4.1e-11 43.4 14.6 0.046 14.1 0.0 8.3 8 0 0 8 8 6 3 ABC transporter AAA_28 PF13521.4 001103809.3_18529001_2 - 5.5e-11 42.8 0.1 0.14 12.2 0.0 6.2 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.20 001103809.3_18529001_2 - 8.3e-11 42.1 0.0 0.61 10.4 0.0 6.3 6 0 0 6 6 6 2 RNA helicase Sigma54_activat PF00158.24 001103809.3_18529001_2 - 1.4e-10 41.0 0.2 0.2 11.2 0.0 6.5 7 0 0 7 7 7 2 Sigma-54 interaction domain T2SSE PF00437.18 001103809.3_18529001_2 - 1.8e-10 40.2 0.6 1.3 7.9 0.0 6.2 6 0 0 6 6 6 3 Type II/IV secretion system protein Sigma54_activ_2 PF14532.4 001103809.3_18529001_2 - 2e-10 40.8 0.6 0.014 15.4 0.0 6.1 7 0 0 7 7 4 2 Sigma-54 interaction domain AAA_33 PF13671.4 001103809.3_18529001_2 - 2.2e-09 37.5 0.2 3.5 7.6 0.0 7.3 7 0 0 7 7 6 1 AAA domain AAA_29 PF13555.4 001103809.3_18529001_2 - 1.2e-08 34.4 2.7 1 9.0 0.0 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain RuvB_N PF05496.10 001103809.3_18529001_2 - 2.1e-08 33.6 0.1 0.059 12.5 0.0 5.8 6 0 0 6 6 5 2 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.10 001103809.3_18529001_2 - 5.3e-08 32.8 0.9 3.2 7.5 0.0 6.5 6 0 0 6 6 5 1 NACHT domain IstB_IS21 PF01695.15 001103809.3_18529001_2 - 1e-07 31.7 2.6 1.4 8.6 0.0 7.3 8 0 0 8 8 7 1 IstB-like ATP binding protein PduV-EutP PF10662.7 001103809.3_18529001_2 - 2e-07 30.7 0.3 0.2 11.2 0.0 5.7 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.4 001103809.3_18529001_2 - 3.2e-07 30.7 0.4 9.2 6.5 0.0 6.0 5 0 0 5 5 5 0 AAA domain DUF815 PF05673.11 001103809.3_18529001_2 - 3.3e-06 26.3 0.2 0.85 8.6 0.0 5.5 6 0 0 6 6 6 1 Protein of unknown function (DUF815) AAA_25 PF13481.4 001103809.3_18529001_2 - 4.5e-06 26.2 0.2 2.2 7.7 0.0 5.5 5 0 0 5 5 5 1 AAA domain cobW PF02492.17 001103809.3_18529001_2 - 1.3e-05 24.8 0.5 1.2 8.6 0.0 6.0 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain VWA PF00092.26 001103809.3_18529001_2 - 1.3e-05 25.5 0.9 1.3e-05 25.5 0.9 2.3 2 0 0 2 2 1 1 von Willebrand factor type A domain dNK PF01712.17 001103809.3_18529001_2 - 6.1e-05 22.8 2.4 0.085 12.6 0.0 5.7 6 0 0 6 6 5 1 Deoxynucleoside kinase VWA_2 PF13519.4 001103809.3_18529001_2 - 0.00011 22.7 0.6 0.002 18.7 0.0 3.2 2 0 0 2 2 2 1 von Willebrand factor type A domain SRP54 PF00448.20 001103809.3_18529001_2 - 0.00013 21.5 0.1 1.8 8.0 0.0 4.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Roc PF08477.11 001103809.3_18529001_2 - 0.00014 21.9 0.2 7.3 6.7 0.0 6.0 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.25 001103809.3_18529001_2 - 0.00047 19.6 0.1 0.11 11.8 0.0 3.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NTPase_1 PF03266.13 001103809.3_18529001_2 - 0.0015 18.3 3.7 15 5.3 0.1 4.9 4 0 0 4 4 4 0 NTPase Cytidylate_kin PF02224.16 001103809.3_18529001_2 - 0.0019 17.8 0.2 15 5.2 0.0 5.2 5 0 0 5 5 5 0 Cytidylate kinase MMR_HSR1 PF01926.21 001103809.3_18529001_2 - 0.0033 17.4 2.3 52 3.8 0.0 6.4 7 0 0 7 7 6 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.15 001103809.3_18529001_2 - 0.0088 15.7 2.5 9.3 5.8 0.0 4.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.16 001103809.3_18529001_2 - 0.016 14.8 0.4 5.3 6.6 0.3 3.4 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.4 001103809.3_18529001_2 - 0.021 14.5 1.5 2.7 7.6 0.0 4.6 5 0 0 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4388 PF14332.4 001103809.3_18529001_2 - 0.081 13.1 1.7 5 7.3 0.0 4.1 4 0 0 4 4 3 0 Domain of unknown function (DUF4388) RBR PF17208.1 001103809.3_18529001_2 - 0.14 12.7 2.9 0.38 11.4 2.9 1.7 1 0 0 1 1 1 0 RNA binding Region DUF1657 PF07870.9 001103809.3_18529001_2 - 3.3 7.5 8.1 0.31 10.8 1.1 3.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1657) PTCB-BRCT PF12738.5 165852.2_18526001_1 - 1.1e-19 70.0 0.3 2.4e-19 68.9 0.3 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.24 165852.2_18526001_1 - 6.4e-12 45.6 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.3 165852.2_18526001_1 - 0.00065 19.9 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.3 165852.2_18526001_1 - 0.0048 17.0 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PEGSRP PF07623.9 165852.2_18526001_3 - 0.37 10.5 2.5 1.2 8.9 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) ODC_AZ PF02100.15 165864.3_18523001_2 - 2.3e-16 59.7 0.0 4.1e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Arv1 PF04161.11 165865.3_18524001_2 - 0.0016 18.5 3.1 0.0024 17.9 3.1 1.2 1 0 0 1 1 1 1 Arv1-like family ODC_AZ PF02100.15 165865.3_18524001_3 - 3e-16 59.3 0.0 6.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Methyltransf_32 PF13679.4 136896.2_18525001_1 - 1.8e-44 151.4 0.6 3e-44 150.7 0.6 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 136896.2_18525001_1 - 0.006 17.1 0.1 0.024 15.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.10 136896.2_18525001_1 - 0.073 13.6 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.4 136896.2_18525001_1 - 0.096 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.12 136896.2_18525001_1 - 0.13 11.7 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Yae1_N PF09811.7 136896.2_18525001_2 - 3.1e-09 36.3 11.7 5.3e-09 35.5 11.7 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Pentapeptide_4 PF13599.4 136912.3_18526001_1 - 0.00012 22.0 0.0 0.0022 17.9 0.0 2.3 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.20 136912.3_18526001_1 - 0.0007 19.0 0.0 0.06 12.9 0.2 2.6 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Reo_sigmaC PF04582.10 136912.3_18526001_1 - 1.3 8.2 16.5 0.22 10.7 2.2 2.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Sec7 PF01369.18 136917.4_18529001_3 - 7.4e-65 218.0 0.5 1.7e-64 216.8 0.5 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.5 136917.4_18529001_3 - 6.3e-25 87.9 2.0 6.3e-25 87.9 2.0 3.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1045 PF06299.10 136917.4_18529001_3 - 0.023 14.6 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) EF-hand_2 PF09068.9 078988.4_18526001_1 - 1e-36 125.7 0.2 1.8e-36 124.8 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.9 078988.4_18526001_1 - 6.3e-25 87.3 0.0 1.4e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand ZZ PF00569.15 078988.4_18526001_1 - 6.9e-08 32.0 10.4 1.3e-07 31.1 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.14 078988.4_18526001_1 - 0.00086 19.4 6.3 0.0018 18.4 6.3 1.5 1 0 0 1 1 1 1 C1 domain zf-HIT PF04438.14 078988.4_18526001_1 - 0.39 10.5 5.6 0.77 9.6 5.6 1.5 1 0 0 1 1 1 0 HIT zinc finger DUF342 PF03961.11 078988.4_18526001_1 - 0.76 8.2 2.3 1.4 7.3 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Surfac_D-trimer PF09006.9 078988.4_18526001_1 - 3.4 7.5 6.0 5.1 6.9 0.3 2.7 1 1 1 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Tnp_zf-ribbon_2 PF13842.4 078988.4_18526001_1 - 4.2 8.1 9.7 9 7.1 9.7 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Ribosomal_L29 PF00831.21 078988.4_18526001_1 - 5 7.0 7.8 0.32 10.9 1.7 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein 7tm_2 PF00002.22 165907.4_18525001_3 - 4.4e-67 225.8 20.9 6.2e-67 225.3 20.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.20 165907.4_18525001_3 - 2.4e-16 59.6 1.8 5.8e-16 58.4 1.8 1.6 1 0 0 1 1 1 1 Hormone receptor domain Homeobox_KN PF05920.9 078990.3_18524001_1 - 1.6e-16 59.8 0.5 3.3e-16 58.8 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.27 078990.3_18524001_1 - 5.7e-06 25.9 0.5 1.1e-05 25.0 0.5 1.5 1 0 0 1 1 1 1 Homeobox domain PDZ PF00595.22 137016.4_18522001_3 - 2.9e-08 33.8 0.0 5.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 137016.4_18522001_3 - 0.0028 17.8 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF3117 PF11314.6 137016.4_18522001_3 - 0.51 10.1 3.1 8.8 6.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3117) Lys PF00062.18 165992.3_18522001_2 - 3e-32 111.4 0.4 3.6e-32 111.1 0.4 1.1 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.18 165992.3_18522001_2 - 0.001 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Spectrin PF00435.19 166016.2_18529001_1 - 1.3e-221 719.7 302.2 1.1e-15 57.8 7.1 40.9 38 3 3 41 41 41 36 Spectrin repeat CH PF00307.29 166016.2_18529001_1 - 2.3e-47 159.6 5.7 7.6e-24 83.9 0.4 4.8 4 0 0 4 4 4 2 Calponin homology (CH) domain GAS2 PF02187.15 166016.2_18529001_1 - 2.8e-32 110.5 0.7 9.8e-32 108.7 0.7 2.1 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_6 PF13405.4 166016.2_18529001_1 - 7.3e-07 28.5 0.5 0.016 14.9 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain ATG16 PF08614.9 166016.2_18529001_1 - 5.7e-06 26.5 2.6 5.7e-06 26.5 2.6 21.1 16 6 6 22 22 13 2 Autophagy protein 16 (ATG16) EF-hand_1 PF00036.30 166016.2_18529001_1 - 7.1e-06 25.1 0.6 0.055 12.9 0.0 3.3 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.6 166016.2_18529001_1 - 3.1e-05 23.6 0.0 0.061 13.0 0.0 3.0 2 0 0 2 2 2 2 CAMSAP CH domain Plectin PF00681.18 166016.2_18529001_1 - 3.6e-05 23.4 0.9 0.022 14.5 0.1 2.8 1 1 1 2 2 2 2 Plectin repeat EF-hand_7 PF13499.4 166016.2_18529001_1 - 3.6e-05 24.0 0.3 3.6e-05 24.0 0.3 5.2 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_8 PF13833.4 166016.2_18529001_1 - 0.00028 20.5 0.7 0.23 11.1 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair Med9 PF07544.11 166016.2_18529001_1 - 0.0071 16.3 0.2 0.0071 16.3 0.2 14.4 15 0 0 15 15 12 2 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.16 166016.2_18529001_1 - 0.013 14.7 0.1 0.013 14.7 0.1 19.7 13 6 6 23 23 23 0 CorA-like Mg2+ transporter protein DUF630 PF04783.10 166016.2_18529001_1 - 0.07 13.2 0.6 2.8 8.1 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF630) EF-hand_5 PF13202.4 166016.2_18529001_1 - 0.076 12.4 2.7 11 5.6 0.1 3.1 2 0 0 2 2 2 0 EF hand HD_5 PF13487.4 166016.2_18529001_1 - 0.15 12.2 6.7 1.2 9.3 0.1 5.0 5 0 0 5 5 4 0 HD domain DUF573 PF04504.12 166016.2_18529001_1 - 0.17 12.4 19.4 3.2 8.3 0.6 9.5 9 0 0 9 9 8 0 Protein of unknown function, DUF573 HEPN PF05168.12 166016.2_18529001_1 - 3.6 7.6 11.6 1.7 8.7 0.3 6.3 5 0 0 5 5 5 0 HEPN domain DUF1940 PF09155.8 166016.2_18529001_1 - 5.2 7.1 7.6 1.7 8.6 0.2 3.9 3 0 0 3 3 2 0 Domain of unknown function (DUF1940) DJ-1_PfpI PF01965.22 137072.1_18522001_1 - 4.6e-46 156.5 0.1 5.5e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.12 137072.1_18522001_1 - 0.097 12.1 0.0 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain RabGAP-TBC PF00566.16 137185.4_18529001_2 - 8.3e-42 143.1 0.9 2.3e-41 141.7 0.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HJURP_C PF12347.6 137185.4_18529001_2 - 0.12 12.3 0.0 0.44 10.5 0.0 2.0 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat ZU5 PF00791.18 137189.3_18529001_1 - 4.6e-17 62.0 0.1 9.4e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.4 137189.3_18529001_1 - 7.6e-12 45.6 0.6 2e-09 37.8 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.14 137189.3_18529001_1 - 2.7e-10 40.0 0.0 1.7e-09 37.5 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain UPA PF17217.1 137189.3_18529001_1 - 8.9e-09 35.4 0.1 1.9e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 UPA domain Ig_2 PF13895.4 137189.3_18529001_1 - 1.1e-07 31.9 0.2 1e-06 28.8 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin domain Death PF00531.20 137189.3_18529001_1 - 4.3e-07 29.9 0.0 7.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Death domain ig PF00047.23 137189.3_18529001_1 - 0.00011 22.1 0.0 0.00069 19.6 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.17 137189.3_18529001_1 - 0.00015 21.7 27.0 0.012 15.7 9.5 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain C2-set_2 PF08205.10 137189.3_18529001_1 - 0.042 13.8 2.7 0.12 12.3 0.0 2.9 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain SPEG_u2 PF16650.3 137189.3_18529001_1 - 0.099 12.7 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Unstructured region on SPEG complex protein Mab-21 PF03281.12 176180.2_18523001_1 - 2.6e-63 214.0 0.9 2.6e-63 214.0 0.9 1.5 2 0 0 2 2 2 1 Mab-21 protein DUF489 PF04356.10 176180.2_18523001_1 - 0.0097 15.8 0.5 0.59 10.0 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF489) Mlf1IP PF10248.7 166122.4_18524001_2 - 5.4e-52 176.0 4.8 5.4e-52 176.0 4.8 2.3 1 1 1 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein YqaJ PF09588.8 137224.3_18523001_1 - 7.1e-41 139.7 0.0 2.4e-31 108.8 0.0 2.3 1 1 0 2 2 2 2 YqaJ-like viral recombinase domain Ins_allergen_rp PF06757.11 137287.2_18522001_1 - 2.8e-50 170.7 0.3 3.2e-50 170.5 0.3 1.0 1 0 0 1 1 1 1 Insect allergen related repeat, nitrile-specifier detoxification DUF4214 PF13946.4 137287.2_18522001_1 - 0.13 12.1 0.1 18 5.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4214) NAD_binding_4 PF07993.10 137296.4_18525001_2 - 3.2e-76 255.8 0.0 4.1e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.17 137296.4_18525001_2 - 1.5e-24 85.8 0.4 3.6e-24 84.7 0.1 1.8 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.17 137296.4_18525001_2 - 1.7e-09 36.9 0.7 6.6e-09 35.0 0.7 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.19 137296.4_18525001_2 - 3.3e-07 29.9 0.1 1e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.22 137296.4_18525001_2 - 0.00047 20.5 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.8 137296.4_18525001_2 - 0.0033 17.2 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.13 137296.4_18525001_2 - 0.0055 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 137296.4_18525001_2 - 0.013 14.5 0.2 0.2 10.6 0.1 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.3 137296.4_18525001_2 - 0.015 14.6 0.2 0.25 10.6 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 137296.4_18525001_2 - 0.039 13.7 0.0 7.6 6.3 0.0 3.0 1 1 0 1 1 1 0 NAD(P)H-binding 7tm_1 PF00001.19 137324.4_18524001_3 - 3.1e-07 29.8 13.1 4.4e-07 29.3 12.6 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF3671 PF12420.6 137324.4_18524001_3 - 3.9 7.4 7.0 3.4 7.6 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function MIF4G PF02854.17 001259451.2_18526001_1 - 1.4e-10 41.1 1.8 2.7e-10 40.2 1.8 1.4 1 0 0 1 1 1 1 MIF4G domain Macoilin PF09726.7 001259451.2_18526001_1 - 0.68 8.3 11.7 1.2 7.5 11.7 1.4 1 0 0 1 1 1 0 Transmembrane protein QIL1 PF15884.3 166211.4_18524001_2 - 7.6e-22 77.6 0.1 3.1e-21 75.6 0.0 2.0 1 1 1 2 2 2 1 Protein QIL1 5_nucleotid_C PF02872.16 166233.4_18525001_3 - 4.9e-41 140.4 0.0 8.2e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.26 166233.4_18525001_3 - 9.3e-07 29.4 0.0 1.6e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lectin_C PF00059.19 001032265.4_18525001_2 - 1.5e-06 28.8 0.3 1.2e-05 25.9 0.3 2.2 1 1 0 1 1 1 1 Lectin C-type domain DUF725 PF05267.10 001038868.3_18522001_1 - 1.2e-29 102.6 3.2 1.2e-29 102.6 3.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF725) MMR_HSR1 PF01926.21 137453.3_18525001_1 - 5.3e-08 32.8 0.0 4.3e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 137453.3_18525001_1 - 0.0011 18.8 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 137453.3_18525001_1 - 0.012 15.0 0.0 0.042 13.3 0.0 1.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Ras PF00071.20 137453.3_18525001_1 - 0.034 13.6 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.16 137453.3_18525001_1 - 0.041 13.3 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.11 137453.3_18525001_1 - 0.087 12.9 0.0 3.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Kelch_1 PF01344.23 137533.4_18526001_2 - 2.6e-69 228.5 21.1 3.2e-12 45.7 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.4 137533.4_18526001_2 - 7.2e-38 127.5 10.4 1.4e-05 25.1 0.1 6.5 1 1 5 6 6 6 6 Kelch motif BACK PF07707.13 137533.4_18526001_2 - 6e-35 119.3 0.6 1.2e-34 118.4 0.6 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.4 137533.4_18526001_2 - 5.6e-21 74.1 0.7 0.0043 16.9 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.13 137533.4_18526001_2 - 3.2e-19 68.0 10.1 0.0022 17.7 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.4 137533.4_18526001_2 - 3.5e-18 65.3 17.3 0.001 19.2 0.1 7.0 7 0 0 7 7 7 6 Galactose oxidase, central domain BTB PF00651.29 137533.4_18526001_2 - 1.8e-10 40.9 0.0 3.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.4 137533.4_18526001_2 - 0.00067 19.4 6.5 2.3 8.2 0.1 5.3 5 0 0 5 5 5 1 Kelch motif BTB PF00651.29 137533.4_18526001_3 - 5.1e-12 45.9 0.0 8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain tRNA-synt_1g PF09334.9 137538.2_18527001_2 - 6.8e-147 489.2 0.0 8.9e-147 488.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.18 137538.2_18527001_2 - 1.1e-35 121.4 32.9 1.6e-12 47.2 6.9 3.6 3 0 0 3 3 3 3 WHEP-TRS domain GST_C_3 PF14497.4 137538.2_18527001_2 - 4.3e-07 29.9 0.1 4e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1 PF00133.20 137538.2_18527001_2 - 7.7e-06 24.3 0.3 0.00077 17.7 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) GST_C PF00043.23 137538.2_18527001_2 - 1.9e-05 24.6 0.1 0.00069 19.7 0.0 3.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 137538.2_18527001_2 - 7.8e-05 22.4 2.3 0.00014 21.6 0.1 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Anticodon_1 PF08264.11 137538.2_18527001_2 - 0.0055 16.5 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA GST_C_6 PF17171.2 137538.2_18527001_2 - 0.022 14.4 0.0 0.06 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF16 PF01519.14 137538.2_18527001_2 - 2.5 8.5 13.1 11 6.5 2.0 3.5 1 1 2 3 3 3 0 Protein of unknown function DUF16 Spectrin PF00435.19 137538.2_18527001_2 - 4.8 7.6 13.7 34 4.9 2.5 3.8 3 0 0 3 3 3 0 Spectrin repeat WH1 PF00568.21 166329.2_18527001_1 - 5.8e-33 113.0 0.4 1.1e-32 112.2 0.4 1.4 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.9 166329.2_18527001_1 - 1.3e-15 56.5 2.3 2.3e-15 55.8 2.3 1.4 1 0 0 1 1 1 1 VASP tetramerisation domain Ran_BP1 PF00638.16 166329.2_18527001_1 - 0.00021 21.4 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain C1_1 PF00130.20 001144242.2_18528001_3 - 3.1e-09 36.4 4.3 5.8e-09 35.6 4.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.28 001144242.2_18528001_3 - 7.1e-09 35.8 0.0 1.8e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain C1_2 PF03107.14 001144242.2_18528001_3 - 0.015 15.5 3.8 0.034 14.3 3.8 1.6 1 0 0 1 1 1 0 C1 domain zf-RING_9 PF13901.4 001144242.2_18528001_3 - 0.03 14.2 1.6 0.059 13.2 1.6 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon BAR PF03114.16 166340.3_18525001_3 - 1.6e-74 250.4 1.6 2.1e-74 250.0 1.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.4 166340.3_18525001_3 - 5e-11 42.1 0.0 8.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.7 166340.3_18525001_3 - 9.1e-06 24.9 0.7 1.3e-05 24.4 0.7 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_2 PF07653.15 166340.3_18525001_3 - 0.0029 17.1 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 166340.3_18525001_3 - 0.16 11.5 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Peptidase_M28 PF04389.15 137573.4_18526001_3 - 1.4e-38 132.4 0.0 2.1e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.26 137573.4_18526001_3 - 0.014 14.9 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Aldolase_II PF00596.19 166351.2_18526001_3 - 6.8e-38 130.3 0.0 1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain EF-hand_7 PF13499.4 137609.3_18522001_3 - 3.4e-11 43.3 0.0 0.00019 21.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 137609.3_18522001_3 - 5.9e-10 38.1 0.2 0.0011 18.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.30 137609.3_18522001_3 - 1.7e-06 27.0 4.5 0.0044 16.3 0.0 3.0 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.8 137609.3_18522001_3 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand ATE_C PF04377.13 058046.5_18524001_1 - 2.1e-49 167.5 1.0 3.6e-49 166.7 1.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.11 058046.5_18524001_1 - 2.6e-21 75.7 12.7 8.1e-21 74.1 12.7 1.9 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Mucin PF01456.15 058046.5_18524001_1 - 0.049 13.5 0.1 0.077 12.9 0.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein EF-hand_7 PF13499.4 137679.3_18522001_3 - 3.2e-14 53.0 2.5 1.8e-10 41.0 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 137679.3_18522001_3 - 6.8e-13 47.0 4.3 0.0002 20.5 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.4 137679.3_18522001_3 - 3.4e-12 45.1 3.5 7.3e-05 22.3 0.2 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.4 137679.3_18522001_3 - 2.5e-06 26.6 4.1 0.00054 19.2 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.4 137679.3_18522001_3 - 0.0061 16.2 7.2 0.074 12.7 0.8 3.1 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 137679.3_18522001_3 - 0.048 13.9 0.6 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Homeobox PF00046.27 001103918.3_18526001_1 - 8.6e-25 86.2 2.8 1.5e-24 85.4 2.8 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001103918.3_18526001_1 - 0.04 13.7 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain TFIIA PF03153.11 001103918.3_18526001_1 - 0.4 10.5 17.6 0.081 12.8 14.0 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Apc15p PF05841.9 001103918.3_18526001_1 - 0.62 10.7 14.1 0.6 10.8 0.6 2.4 2 0 0 2 2 2 0 Apc15p protein SelP_N PF04592.12 001103918.3_18526001_1 - 1.1 8.5 8.5 2.2 7.5 8.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ANF_receptor PF01094.26 166415.2_18527001_1 - 9.6e-79 264.9 0.0 1.3e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Guanylate_cyc PF00211.18 166415.2_18527001_1 - 6.5e-68 227.8 0.0 1.3e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.15 166415.2_18527001_1 - 1.2e-43 149.1 0.0 1.9e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 166415.2_18527001_1 - 1e-33 116.7 0.0 1.7e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.12 166415.2_18527001_1 - 8.2e-06 25.3 1.0 1.6e-05 24.3 1.0 1.5 1 0 0 1 1 1 1 Heme NO binding associated YajC PF02699.13 166415.2_18527001_1 - 0.014 15.1 0.1 0.58 10.0 0.1 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit DUF2102 PF09875.7 166415.2_18527001_3 - 0.51 10.0 3.2 8.5 6.0 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) RIC3 PF15361.4 166418.4_18525001_2 - 1.6e-36 125.8 1.6 2.6e-36 125.0 0.0 2.1 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 UDPGT PF00201.16 137720.4_18524001_1 - 3.8e-85 286.4 2.2 5.3e-85 286.0 2.2 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_4 PF13579.4 137720.4_18524001_1 - 0.0046 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.4 137720.4_18524001_1 - 0.0081 16.0 0.1 0.065 13.1 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 RSN1_TM PF13967.4 137720.4_18524001_1 - 0.026 14.2 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport ABC_tran PF00005.25 137727.3_18529001_1 - 5.7e-52 175.7 0.2 2.6e-26 92.6 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.21 137727.3_18529001_1 - 8.8e-52 176.3 36.5 4.7e-32 111.6 16.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.17 137727.3_18529001_1 - 1.3e-09 37.7 10.9 0.049 12.9 0.7 4.9 3 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.21 137727.3_18529001_1 - 1.1e-07 31.8 0.1 0.015 15.2 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.4 137727.3_18529001_1 - 1.1e-07 31.3 0.4 0.0083 15.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.4 137727.3_18529001_1 - 1.5e-06 28.1 1.8 0.031 14.0 0.1 3.7 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF258 PF03193.14 137727.3_18529001_1 - 2.6e-05 24.0 0.1 0.05 13.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.21 137727.3_18529001_1 - 0.00014 21.8 1.5 0.085 12.8 0.2 2.5 2 0 0 2 2 2 2 Dynamin family DUF815 PF05673.11 137727.3_18529001_1 - 0.00023 20.3 0.2 0.017 14.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.4 137727.3_18529001_1 - 0.00033 20.9 0.1 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.20 137727.3_18529001_1 - 0.00039 19.4 0.3 0.043 12.7 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain TrwB_AAD_bind PF10412.7 137727.3_18529001_1 - 0.001 17.9 1.8 0.97 8.1 0.1 2.7 2 1 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.4 137727.3_18529001_1 - 0.0012 19.0 0.2 2 8.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.4 137727.3_18529001_1 - 0.0016 18.9 9.1 0.05 14.0 0.1 2.6 3 0 0 3 3 2 2 AAA domain ArgK PF03308.14 137727.3_18529001_1 - 0.0023 16.8 0.2 1.5 7.6 0.0 2.3 2 0 0 2 2 2 2 ArgK protein DUF87 PF01935.15 137727.3_18529001_1 - 0.0028 17.6 2.4 0.34 10.8 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.16 137727.3_18529001_1 - 0.0033 16.7 0.2 3.2 6.9 0.0 2.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family Roc PF08477.11 137727.3_18529001_1 - 0.0097 16.0 0.5 1.3 9.2 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.4 137727.3_18529001_1 - 0.011 15.3 0.2 3.6 7.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.17 137727.3_18529001_1 - 0.029 13.8 0.6 0.46 9.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.10 137727.3_18529001_1 - 0.032 13.4 0.3 5.9 6.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.25 137727.3_18529001_1 - 0.069 12.5 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.4 137727.3_18529001_1 - 0.07 13.5 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.13 137727.3_18529001_1 - 0.074 12.8 0.7 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 NTPase Adeno_IVa2 PF02456.13 137727.3_18529001_1 - 0.086 11.5 0.9 1.2 7.7 0.0 2.5 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA_15 PF13175.4 137727.3_18529001_1 - 0.089 12.3 0.7 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.12 166442.3_18529001_3 - 2.1e-126 421.4 0.0 3.1e-126 420.9 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Ank_2 PF12796.5 166442.3_18529001_3 - 2e-68 226.9 12.3 2.2e-16 60.1 0.0 6.3 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.4 166442.3_18529001_3 - 8.8e-51 169.5 2.5 3.7e-10 40.0 0.2 7.7 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.4 166442.3_18529001_3 - 2.4e-44 144.1 7.2 0.00025 21.1 0.0 12.0 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.28 166442.3_18529001_3 - 1.8e-43 145.0 9.4 0.00013 22.1 0.1 11.8 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.4 166442.3_18529001_3 - 3e-43 145.0 14.1 3.5e-07 30.3 0.3 9.5 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Tmemb_55A PF09788.7 166442.3_18529001_3 - 6.8 5.6 8.2 0.48 9.3 1.5 2.1 2 0 0 2 2 2 0 Transmembrane protein 55A SNF2_N PF00176.21 176244.3_18529001_1 - 6.7e-67 225.5 3.3 1.6e-66 224.3 3.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.11 176244.3_18529001_1 - 2.7e-21 75.5 7.5 2.7e-21 75.5 7.5 5.2 5 1 1 6 6 6 1 HSA Helicase_C PF00271.29 176244.3_18529001_1 - 4.5e-20 72.0 2.1 9.5e-20 70.9 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ndr PF03096.12 206193.2_18526001_1 - 8.5e-100 333.0 0.0 1.1e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.18 206193.2_18526001_1 - 0.00047 19.7 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 206193.2_18526001_1 - 0.0013 19.3 0.1 0.0017 18.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Atrophin-1 PF03154.13 206193.2_18526001_1 - 0.18 9.9 3.1 0.26 9.4 3.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Spec3 PF15795.3 137759.5_18529001_3 - 1.6e-28 99.0 12.5 2.8e-28 98.2 12.5 1.4 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein TMEM213 PF15192.4 137759.5_18529001_3 - 0.07 13.0 1.2 0.32 10.9 1.2 2.2 1 0 0 1 1 1 0 TMEM213 family YscO PF07321.10 137759.5_18529001_3 - 9.9 6.0 9.6 0.84 9.5 0.8 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO MADF_DNA_bdg PF10545.7 166478.4_18523001_2 - 1.8e-09 37.6 0.0 2.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like WH2 PF02205.18 137796.3_18527001_3 - 4.4e-10 38.9 1.7 1e-09 37.7 1.7 1.7 1 0 0 1 1 1 1 WH2 motif Med16 PF11635.6 137806.4_18526001_2 - 5.8e-120 401.4 0.0 7.2e-120 401.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.5 137806.4_18526001_2 - 0.0079 16.3 0.7 0.34 11.1 0.0 3.7 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.5 166560.4_18524001_2 - 3.4e-11 43.4 0.1 6.2e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 166560.4_18524001_2 - 1.5e-05 25.3 0.0 0.013 15.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 166560.4_18524001_2 - 5.8e-05 23.1 0.1 0.39 11.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.4 166560.4_18524001_2 - 0.00091 19.4 0.3 0.036 14.3 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.28 166560.4_18524001_2 - 0.036 14.4 0.1 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.5 137876.4_18525001_2 - 1.5e-26 92.7 1.1 3.3e-12 46.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.4 137876.4_18525001_2 - 1.4e-21 76.1 0.2 9.4e-09 35.3 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.4 137876.4_18525001_2 - 1.2e-18 67.1 1.8 1.1e-07 32.2 0.0 5.1 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.28 137876.4_18525001_2 - 6.5e-17 61.0 0.9 0.0037 17.5 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.4 137876.4_18525001_2 - 6.8e-17 59.7 0.9 0.0027 17.9 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Dpy-30 PF05186.11 137876.4_18525001_2 - 7.2e-16 57.5 0.1 1.5e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Dpy-30 motif PAS_9 PF13426.5 137876.4_18525001_2 - 0.011 15.8 0.1 7.3 6.8 0.0 3.1 3 0 0 3 3 3 0 PAS domain MFS_1 PF07690.14 137878.2_18524001_3 - 6.9e-48 163.2 34.4 3.5e-45 154.3 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 137878.2_18524001_3 - 8e-13 47.9 11.2 8e-13 47.9 11.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter CPP1-like PF11833.6 137878.2_18524001_3 - 0.44 10.0 2.3 1 8.9 2.2 1.7 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DOMON PF03351.15 079091.4_18529001_1 - 1.8e-56 189.6 0.6 3.5e-32 111.1 0.2 3.6 3 0 0 3 3 3 3 DOMON domain Trypan_PARP PF05887.9 079091.4_18529001_1 - 1.5e-10 41.1 183.7 0.00022 21.1 43.3 4.7 1 1 3 4 4 4 4 Procyclic acidic repetitive protein (PARP) EGF_2 PF07974.11 079091.4_18529001_1 - 3.2e-09 36.9 23.0 1.4e-06 28.4 10.5 3.1 2 0 0 2 2 2 2 EGF-like domain SEA PF01390.18 079091.4_18529001_1 - 0.0062 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 SEA domain 7tm_7 PF08395.10 166586.1_18523001_1 - 7.5e-58 196.4 34.1 8.5e-58 196.2 34.1 1.0 1 0 0 1 1 1 1 7tm Chemosensory receptor Rib_5-P_isom_A PF06026.12 166594.2_18523001_1 - 2e-59 199.9 0.0 2.8e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) NHL PF01436.19 080379.5_18524001_2 - 5.9e-18 63.8 0.3 2.5e-05 23.9 0.0 5.8 6 0 0 6 6 6 4 NHL repeat Phytase-like PF13449.4 080379.5_18524001_2 - 0.012 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Esterase-like activity of phytase ADK PF00406.20 079112.4_18523001_2 - 3.4e-61 205.7 0.0 4.2e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.4 079112.4_18523001_2 - 3.1e-24 85.8 0.0 6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.12 079112.4_18523001_2 - 2.5e-14 52.9 0.0 5.7e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.4 079112.4_18523001_2 - 0.003 18.0 0.0 0.0084 16.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.16 079112.4_18523001_2 - 0.13 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase XPC-binding PF09280.9 138063.2_18522001_3 - 0.71 9.5 11.4 0.051 13.2 2.2 2.2 2 0 0 2 2 2 0 XPC-binding domain Pkinase PF00069.23 206214.4_18529001_2 - 1.4e-64 217.9 0.0 4.4e-64 216.2 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain PKK PF12474.6 206214.4_18529001_2 - 4.1e-62 208.2 85.5 2.3e-33 115.1 38.1 5.5 6 1 1 7 7 7 2 Polo kinase kinase Pkinase_Tyr PF07714.15 206214.4_18529001_2 - 4.3e-50 170.3 0.1 4.3e-50 170.3 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1091 PF06477.11 138074.2_18522001_1 - 5.6e-24 84.3 1.2 5.6e-24 84.3 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1091) E1_DerP2_DerF2 PF02221.13 138074.2_18522001_1 - 0.0047 17.2 0.0 0.0067 16.7 0.0 1.2 1 0 0 1 1 1 1 ML domain DUF3398 PF11878.6 138074.2_18522001_1 - 0.12 12.6 0.0 0.46 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) BRCA2 PF00634.16 138081.4_18527001_1 - 7.5e-11 41.2 5.2 0.0065 15.8 0.0 3.8 3 0 0 3 3 3 3 BRCA2 repeat PSP PF04046.14 001038882.3_18526001_2 - 6.5e-13 48.2 0.1 1.2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.21 001038882.3_18526001_2 - 0.0002 21.2 0.7 0.00042 20.1 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Vps55 PF04133.12 166691.4_18522001_2 - 1.9e-31 108.3 9.2 2.6e-31 107.9 9.2 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting 55 NKAIN PF05640.12 166694.3_18528001_3 - 6.1e-96 319.3 4.6 8.2e-96 318.9 4.6 1.2 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Ion_trans PF00520.29 166696.5_18529001_1 - 7.3e-226 745.7 101.1 3.8e-63 212.8 25.4 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.3 166696.5_18529001_1 - 9.7e-11 41.2 0.0 2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.10 166696.5_18529001_1 - 4.3e-07 28.8 83.3 4.1e-05 22.3 5.1 8.7 7 3 3 10 10 10 7 Polycystin cation channel CD36 PF01130.19 166702.3_18525001_1 - 1.1e-151 505.4 0.0 1.3e-151 505.1 0.0 1.1 1 0 0 1 1 1 1 CD36 family TMEM51 PF15345.4 166702.3_18525001_1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 IncA PF04156.12 166702.3_18525001_1 - 0.32 10.6 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 IncA protein Pkinase PF00069.23 078950.4_18523001_3 - 6.1e-66 222.3 0.0 7.3e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 078950.4_18523001_3 - 5e-35 120.9 0.0 7.5e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 078950.4_18523001_3 - 8.8e-05 21.8 0.1 0.0021 17.3 0.1 2.1 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.20 078950.4_18523001_3 - 0.0053 16.2 0.1 0.0087 15.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family PRA1 PF03208.17 136695.3_18523001_1 - 3.8e-32 110.7 10.7 5.3e-32 110.3 10.7 1.1 1 0 0 1 1 1 1 PRA1 family protein Asp PF00026.21 001347753.1_18524001_2 - 9.1e-122 406.2 0.0 1.1e-121 406.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001347753.1_18524001_2 - 3e-14 53.5 0.2 1.5e-12 48.0 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.4 001347753.1_18524001_2 - 1.2e-06 28.3 0.0 4.2e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal A1_Propeptide PF07966.10 001347753.1_18524001_2 - 2.9e-06 26.9 0.0 5.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 A1 Propeptide Synaptobrevin PF00957.19 001299326.1_18523001_3 - 1.3e-30 104.9 1.0 2.3e-30 104.1 1.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.4 001299326.1_18523001_3 - 4.9e-22 77.6 0.8 8.1e-22 76.9 0.8 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF808 PF05661.10 001299326.1_18523001_3 - 0.15 11.0 0.6 0.28 10.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF808) MADF_DNA_bdg PF10545.7 136446.3_18525001_1 - 6.5e-24 83.9 7.5 1.4e-15 57.3 0.2 2.9 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-C2H2 PF00096.24 136446.3_18525001_1 - 2.8e-17 62.0 47.9 0.00042 20.5 1.6 7.7 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 136446.3_18525001_1 - 1.3e-15 56.6 46.5 0.022 15.4 3.1 7.9 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.4 136446.3_18525001_1 - 1.3e-14 53.7 40.0 1.1e-05 25.6 0.3 8.0 8 0 0 8 8 7 5 Zinc-finger double domain zf-C2H2_jaz PF12171.6 136446.3_18525001_1 - 1.6e-06 28.1 42.0 0.0036 17.4 0.4 7.7 8 0 0 8 8 7 4 Zinc-finger double-stranded RNA-binding PHD PF00628.27 136446.3_18525001_1 - 0.026 14.3 0.6 0.026 14.3 0.6 3.7 3 1 0 3 3 3 0 PHD-finger zinc_ribbon_15 PF17032.3 136446.3_18525001_1 - 0.03 14.9 13.0 0.9 10.2 0.5 3.9 2 1 1 3 3 3 0 zinc-ribbon family PyrI_C PF02748.13 136446.3_18525001_1 - 0.042 13.6 0.3 0.042 13.6 0.3 6.4 7 1 1 8 8 8 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Myb_DNA-bind_3 PF12776.5 136446.3_18525001_1 - 0.056 14.1 0.2 0.22 12.2 0.0 2.0 2 0 0 2 2 1 0 Myb/SANT-like DNA-binding domain zf-C2H2_6 PF13912.4 136446.3_18525001_1 - 0.067 13.0 35.5 0.27 11.1 0.2 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger E2F_TDP PF02319.18 136446.3_18525001_1 - 0.084 12.8 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain HNH PF01844.21 136446.3_18525001_1 - 0.46 10.6 23.0 4.1 7.5 0.3 6.0 6 0 0 6 6 6 0 HNH endonuclease zf-Di19 PF05605.10 136446.3_18525001_1 - 0.53 10.5 37.7 0.035 14.2 2.0 5.9 4 1 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.6 136446.3_18525001_1 - 1 9.6 5.7 11 6.2 0.1 3.1 3 0 0 3 3 3 0 zinc-finger-containing domain zf-BED PF02892.13 136446.3_18525001_1 - 1.8 8.6 30.5 0.19 11.7 0.3 6.6 4 2 1 5 5 5 0 BED zinc finger zf-C2H2_8 PF15909.3 136446.3_18525001_1 - 1.8 8.8 16.3 0.15 12.3 3.0 3.5 1 1 2 3 3 3 0 C2H2-type zinc ribbon UBZ_FAAP20 PF15750.3 136446.3_18525001_1 - 5.8 6.8 7.5 9.9 6.1 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger zf-C2H2 PF00096.24 136677.3_18523001_1 - 8.9e-15 54.1 48.5 0.0007 19.8 0.8 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 136677.3_18523001_1 - 1.2e-07 31.8 53.1 0.012 16.2 4.4 8.2 8 0 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 136677.3_18523001_1 - 9.4e-07 28.9 35.5 0.11 12.9 2.3 7.4 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_jaz PF12171.6 136677.3_18523001_1 - 0.0063 16.7 4.4 0.042 14.0 1.3 5.9 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 136677.3_18523001_1 - 0.33 11.0 17.8 0.046 13.7 3.4 3.8 4 0 0 4 4 4 0 Zinc ribbon domain Rad50_zn_hook PF04423.12 136677.3_18523001_1 - 0.47 10.2 4.0 0.96 9.2 0.9 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif Arc_trans_TRASH PF08394.8 136677.3_18523001_1 - 1.2 9.4 7.4 0.82 9.9 1.2 3.5 3 0 0 3 3 3 0 Archaeal TRASH domain zinc_ribbon_9 PF14369.4 136677.3_18523001_1 - 4.1 7.6 17.7 0.43 10.7 0.5 4.6 4 0 0 4 4 4 0 zinc-ribbon Abhydrolase_1 PF00561.18 001299240.1_18524001_1 - 4e-22 78.9 0.0 5.4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001299240.1_18524001_1 - 8.8e-17 62.3 0.0 1.4e-16 61.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001299240.1_18524001_1 - 1.8e-16 60.0 0.0 3.8e-16 59.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.12 001299240.1_18524001_1 - 1.4e-05 23.8 0.0 2.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.5 001299240.1_18524001_1 - 0.00014 21.5 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.18 001299240.1_18524001_1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.11 001299240.1_18524001_1 - 0.0044 16.6 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.7 001299240.1_18524001_1 - 0.0044 16.5 0.0 0.014 14.9 0.0 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase PAF-AH_p_II PF03403.11 001299240.1_18524001_1 - 0.04 12.3 0.0 0.1 10.9 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF915 PF06028.9 001299240.1_18524001_1 - 0.046 12.9 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.18 001299240.1_18524001_1 - 0.082 12.9 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Peptidase_S9 PF00326.19 001299240.1_18524001_1 - 0.13 11.6 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family CRAL_TRIO PF00650.18 165689.3_18524001_3 - 2.7e-21 75.8 0.0 7.1e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.13 165689.3_18524001_3 - 0.034 14.2 0.4 0.071 13.2 0.4 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain DAGAT PF03982.11 001299232.1_18523001_2 - 2.5e-82 276.0 0.0 3.3e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase TMPIT PF07851.11 001299232.1_18523001_2 - 0.35 9.9 3.1 0.57 9.2 3.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.23 176112.2_18529001_3 - 5.7e-62 209.3 0.0 9.3e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 176112.2_18529001_3 - 1.6e-38 132.4 0.0 3e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.14 176112.2_18529001_3 - 2.6e-37 126.6 38.8 1.7e-14 53.5 1.4 4.4 4 0 0 4 4 4 3 Hr1 repeat Pkinase_C PF00433.22 176112.2_18529001_3 - 1.5e-11 44.7 0.5 1.5e-11 44.7 0.5 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.4 176112.2_18529001_3 - 5.6e-06 25.7 0.3 2.7e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like VPS13_mid_rpt PF16910.3 001273852.1_18529001_2 - 8.7e-73 244.5 12.2 8.1e-61 205.3 0.2 5.5 5 0 0 5 5 5 2 Repeating coiled region of VPS13 VPS13_C PF16909.3 001273852.1_18529001_2 - 1e-64 217.4 2.9 2.6e-60 203.1 0.2 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.3 001273852.1_18529001_2 - 1.7e-63 214.4 6.6 3.8e-61 206.8 0.3 4.7 5 0 0 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.10 001273852.1_18529001_2 - 3.7e-49 167.4 0.0 2e-48 165.0 0.0 2.3 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.5 001273852.1_18529001_2 - 3.5e-40 136.6 1.2 3.8e-39 133.3 0.8 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.9 001273852.1_18529001_2 - 1.3e-05 25.3 0.0 5.8e-05 23.2 0.0 2.2 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Apt1 PF10351.7 001273852.1_18529001_2 - 0.006 15.4 2.6 2.7 6.6 0.3 4.0 4 0 0 4 4 4 1 Golgi-body localisation protein domain HTH_psq PF05225.14 165790.3_18529001_1 - 3.4e-51 170.6 2.2 4.7e-15 54.9 0.0 4.5 4 0 0 4 4 4 4 helix-turn-helix, Psq domain BTB PF00651.29 165790.3_18529001_1 - 5.9e-21 74.6 0.1 1.6e-20 73.2 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain HTH_28 PF13518.4 165790.3_18529001_1 - 2e-07 30.9 0.4 0.32 11.0 0.0 4.7 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_23 PF13384.4 165790.3_18529001_1 - 0.0013 18.4 0.1 1.6 8.5 0.0 4.0 4 0 0 4 4 4 1 Homeodomain-like domain RWP-RK PF02042.13 165790.3_18529001_1 - 0.073 12.9 0.0 12 5.9 0.0 3.5 3 0 0 3 3 3 0 RWP-RK domain HTH_psq PF05225.14 165791.3_18529001_1 - 3.9e-54 180.0 1.1 4.2e-15 55.1 0.0 4.5 4 0 0 4 4 4 4 helix-turn-helix, Psq domain HTH_28 PF13518.4 165791.3_18529001_1 - 8.9e-08 32.0 0.8 0.28 11.2 0.0 4.7 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_23 PF13384.4 165791.3_18529001_1 - 0.00031 20.3 0.1 1.4 8.7 0.0 4.0 4 0 0 4 4 4 1 Homeodomain-like domain RWP-RK PF02042.13 165791.3_18529001_1 - 0.052 13.4 0.0 10 6.0 0.0 3.5 3 0 0 3 3 3 0 RWP-RK domain HTH_7 PF02796.13 165791.3_18529001_1 - 0.078 12.9 0.0 5.1 7.1 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase EIIBC-GUT_N PF03612.12 001014519.3_18529001_1 - 0.28 10.8 4.7 0.69 9.5 4.7 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF719 PF05334.11 001014519.3_18529001_1 - 6.1 6.9 14.9 5.6 7.0 9.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) HTH_psq PF05225.14 001014519.3_18529001_3 - 4.2e-54 179.9 1.1 4.3e-15 55.0 0.0 4.6 4 0 0 4 4 4 4 helix-turn-helix, Psq domain HTH_28 PF13518.4 001014519.3_18529001_3 - 6.9e-08 32.4 0.8 0.29 11.2 0.0 5.0 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_23 PF13384.4 001014519.3_18529001_3 - 0.00028 20.5 0.1 1.5 8.6 0.0 4.2 4 0 0 4 4 4 1 Homeodomain-like domain TFIIA PF03153.11 001014519.3_18529001_3 - 0.0034 17.3 67.8 0.026 14.4 37.8 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit RWP-RK PF02042.13 001014519.3_18529001_3 - 0.061 13.2 0.0 11 6.0 0.0 3.5 3 0 0 3 3 3 0 RWP-RK domain HTH_7 PF02796.13 001014519.3_18529001_3 - 0.08 12.9 0.0 5.3 7.1 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase DDHD PF02862.15 001014519.3_18529001_3 - 0.74 9.8 22.9 0.25 11.3 14.5 2.5 2 0 0 2 2 2 0 DDHD domain HTH_psq PF05225.14 001316414.1_18529001_1 - 6.5e-52 172.9 1.4 5.8e-15 54.6 0.0 4.5 4 0 0 4 4 4 4 helix-turn-helix, Psq domain BTB PF00651.29 001316414.1_18529001_1 - 7.9e-21 74.2 0.1 2e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain HTH_28 PF13518.4 001316414.1_18529001_1 - 1.2e-07 31.5 0.7 0.38 10.8 0.0 4.9 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_23 PF13384.4 001316414.1_18529001_1 - 0.00072 19.2 0.1 1.9 8.2 0.0 4.0 4 0 0 4 4 4 1 Homeodomain-like domain GGACT PF06094.10 001259585.2_18522001_3 - 1.9e-26 92.9 0.1 2.6e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.4 001259585.2_18522001_3 - 1.2e-05 25.4 0.3 4e-05 23.8 0.3 1.8 2 0 0 2 2 2 1 AIG2-like family zf-C2H2 PF00096.24 138017.2_18524001_1 - 1.8e-20 72.0 48.7 7e-06 26.1 2.8 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 138017.2_18524001_1 - 3.6e-19 68.1 57.1 1.2e-09 38.0 1.4 7.6 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 138017.2_18524001_1 - 1.8e-14 53.1 48.6 0.00015 22.2 1.5 6.0 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_8 PF15909.3 138017.2_18524001_1 - 0.00047 20.3 11.0 0.01 16.0 4.4 3.3 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.4 138017.2_18524001_1 - 0.00094 18.9 2.4 0.0074 16.1 0.3 5.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 138017.2_18524001_1 - 0.0033 17.6 0.6 0.0033 17.6 0.6 5.6 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.3 138017.2_18524001_1 - 0.2 12.3 10.3 0.94 10.1 2.4 3.0 2 1 0 2 2 2 0 zinc-ribbon family zf-C2HE PF16278.3 138017.2_18524001_1 - 5.4 7.4 27.1 1.2 9.5 0.2 4.6 2 2 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF829 PF05705.12 166583.2_18524001_1 - 9.9e-54 182.6 1.3 1.5e-53 182.1 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.16 166583.2_18524001_1 - 0.0083 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family M16C_assoc PF08367.9 001043005.2_18527001_3 - 2.8e-65 219.8 0.1 4e-65 219.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.19 001043005.2_18527001_3 - 6.9e-25 88.0 2.4 8.4e-19 68.2 0.1 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.18 001043005.2_18527001_3 - 4.5e-07 29.8 1.3 8.3e-05 22.5 0.0 3.3 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) DUF4898 PF16239.3 001043005.2_18527001_3 - 0.075 13.2 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) DUF1690 PF07956.9 001043005.2_18527001_3 - 0.098 12.9 0.3 0.22 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) RRM_1 PF00076.20 137925.3_18523001_3 - 7.7e-36 121.6 0.9 1.3e-13 50.4 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 137925.3_18523001_3 - 4.9e-05 23.2 0.0 0.056 13.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.3 137925.3_18523001_3 - 0.00067 19.3 0.0 5.1 6.9 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM PF05172.11 137925.3_18523001_3 - 0.11 12.3 0.0 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Glyco_transf_49 PF13896.4 138042.4_18524001_2 - 4e-104 348.4 4.9 4.8e-104 348.1 4.9 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan PDCD2_C PF04194.11 001299899.1_18523001_1 - 2.6e-46 157.6 2.0 2.7e-43 147.8 0.1 2.4 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.16 001299899.1_18523001_1 - 1.7e-08 34.2 19.2 1.7e-08 34.2 19.2 2.9 3 1 0 3 3 3 1 MYND finger DKCLD PF08068.10 080381.5_18524001_1 - 1e-31 108.7 0.6 5e-31 106.5 0.2 2.4 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.16 080381.5_18524001_1 - 5.6e-22 78.6 0.2 3.8e-19 69.4 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.3 080381.5_18524001_1 - 2.7e-19 68.9 0.9 5.4e-19 68.0 0.9 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.18 080381.5_18524001_1 - 5.2e-18 64.6 0.8 1.2e-17 63.5 0.8 1.7 1 0 0 1 1 1 1 PUA domain Coilin_N PF15862.3 080381.5_18524001_1 - 0.0058 16.3 4.6 0.0058 16.3 4.6 2.1 2 0 0 2 2 2 1 Coilin N-terminus Med19 PF10278.7 080381.5_18524001_1 - 1 9.1 23.5 0.086 12.6 16.0 2.4 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 DUF908 PF06012.10 080381.5_18524001_1 - 5.7 6.1 7.8 9 5.5 7.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RNA_polI_A34 PF08208.9 080381.5_18524001_1 - 8.9 6.2 36.3 1.6 8.7 28.7 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Metallophos PF00149.26 001259562.1_18526001_3 - 3.2e-20 73.4 2.1 3.2e-20 73.4 2.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SapB_1 PF05184.13 001259562.1_18526001_3 - 0.0077 16.1 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 1 PP2C_2 PF13672.4 001259562.1_18526001_3 - 0.084 12.4 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_8 PF13855.4 166526.2_18527001_1 - 6.7e-10 38.5 21.5 7.7e-06 25.5 11.6 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.5 166526.2_18527001_1 - 8.9e-07 29.0 20.0 0.0012 19.0 2.2 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.4 166526.2_18527001_1 - 0.051 13.5 15.9 0.74 9.9 0.4 4.8 5 0 0 5 5 5 0 Leucine Rich repeat Cyclin_N PF00134.21 166557.3_18526001_2 - 6.4e-37 126.1 0.3 1.5e-36 124.9 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 166557.3_18526001_2 - 4.5e-36 123.4 0.1 9.1e-36 122.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain MENTAL PF10457.7 001259566.2_18525001_2 - 2.9e-68 229.0 12.9 4.3e-68 228.5 12.9 1.2 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.17 001259566.2_18525001_2 - 1.6e-23 83.1 0.0 1.3e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 START domain Arm PF00514.21 057957.5_18527001_1 - 2.8e-05 23.9 12.4 3.2 7.8 0.0 7.1 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.4 057957.5_18527001_1 - 0.0052 17.0 3.0 0.61 10.4 0.0 4.5 4 2 1 5 5 5 1 HEAT repeats KH_1 PF00013.27 001299793.1_18524001_1 - 8.4e-11 41.4 0.0 2.3e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 KH domain Forkhead PF00250.16 079090.3_18525001_2 - 3.7e-36 123.2 0.0 5.8e-36 122.5 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain LysM PF01476.18 137258.3_18522001_1 - 0.012 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 LysM domain DUF505 PF04458.10 137258.3_18522001_1 - 0.1 10.8 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) zf-CCHC PF00098.21 137895.3_18526001_2 - 2.2e-36 122.2 51.0 4.4e-07 29.5 1.1 6.7 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.4 137895.3_18526001_2 - 3.3e-05 23.3 31.1 0.74 9.4 0.4 6.5 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.4 137895.3_18526001_2 - 3.4e-05 23.4 2.6 3.4e-05 23.4 2.6 6.7 7 0 0 7 7 7 4 Zinc knuckle zf-CCHC_5 PF14787.4 137895.3_18526001_2 - 5.4 6.7 40.8 0.63 9.7 1.5 6.3 5 1 1 6 6 6 0 GAG-polyprotein viral zinc-finger CD36 PF01130.19 001299945.1_18525001_3 - 7.6e-121 403.7 0.5 1e-120 403.3 0.5 1.1 1 0 0 1 1 1 1 CD36 family DUF2162 PF09930.7 001299945.1_18525001_3 - 0.12 11.7 2.0 0.34 10.2 0.0 2.0 2 0 0 2 2 2 0 Predicted transporter (DUF2162) RAWUL PF16207.3 001299439.1_18529001_1 - 1.2e-15 57.8 1.4 3.7e-15 56.2 1.4 2.0 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.4 001299439.1_18529001_1 - 4.9e-07 29.3 11.1 9.8e-07 28.4 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001299439.1_18529001_1 - 2.3e-06 27.3 12.4 5e-06 26.2 12.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001299439.1_18529001_1 - 0.0056 16.8 12.0 0.012 15.7 12.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.4 001299439.1_18529001_1 - 0.0075 16.0 10.8 0.016 14.9 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001299439.1_18529001_1 - 0.081 12.8 9.1 0.2 11.6 9.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.4 001299439.1_18529001_1 - 0.088 12.7 14.2 0.34 10.8 13.7 2.2 1 1 0 1 1 1 0 zinc-RING finger domain DZR PF12773.5 001299439.1_18529001_1 - 0.25 11.3 4.5 0.55 10.2 4.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.10 001299439.1_18529001_1 - 1.3 8.9 4.6 2.6 8.0 4.6 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-C3HC4_4 PF15227.4 001299439.1_18529001_1 - 3.9 7.6 14.9 0.76 9.8 9.9 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.5 001299439.1_18529001_1 - 9.1 6.5 10.1 27 5.0 10.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain PFK PF00365.18 001273918.1_18527001_1 - 1e-187 622.0 0.9 1.5e-93 313.0 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase PUB PF09409.8 166664.1_18529001_3 - 7.1e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 PUB domain LSM PF01423.20 137715.4_18522001_1 - 8.7e-16 57.2 0.3 1.3e-15 56.7 0.3 1.3 1 0 0 1 1 1 1 LSM domain PUF PF00806.17 137715.4_18522001_1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat HMG_CoA_synt_C PF08540.8 079972.4_18526001_1 - 7e-104 347.2 1.6 9.7e-104 346.8 1.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.15 079972.4_18526001_1 - 8.6e-98 325.2 0.1 1.3e-97 324.6 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.8 079972.4_18526001_1 - 0.16 11.7 0.4 0.38 10.5 0.4 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 7tm_1 PF00001.19 079120.3_18529001_1 - 1e-74 251.0 0.2 2.2e-74 249.9 0.0 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 079120.3_18529001_1 - 1.2e-06 28.0 4.5 5.6e-05 22.5 0.5 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 079120.3_18529001_1 - 2.3e-05 23.7 2.8 4.5e-05 22.8 2.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 079120.3_18529001_1 - 9.8e-05 22.1 0.3 0.0002 21.1 0.3 1.4 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.7 079120.3_18529001_1 - 0.23 10.8 10.8 0.021 14.2 5.2 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc BAF1_ABF1 PF04684.11 001103947.2_18529001_2 - 8.3 5.1 13.9 22 3.7 13.9 1.7 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lipocalin PF00061.21 079003.5_18523001_1 - 6.7e-10 39.2 0.0 1.5e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.10 079003.5_18523001_1 - 5.2e-05 23.1 0.0 0.00042 20.2 0.0 2.1 2 0 0 2 2 2 1 Lipocalin-like domain Triabin PF03973.11 079003.5_18523001_1 - 0.0028 17.4 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Triabin GST_N PF02798.18 137011.3_18523001_3 - 1.4e-12 47.6 0.0 1.5e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 137011.3_18523001_3 - 2.3e-12 47.0 0.0 5.9e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 137011.3_18523001_3 - 2.6e-08 33.9 0.0 4.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 137011.3_18523001_3 - 3.6e-07 30.2 0.0 6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 137011.3_18523001_3 - 8.7e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 137011.3_18523001_3 - 0.0001 22.0 0.1 0.00019 21.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 137011.3_18523001_3 - 0.089 13.4 0.0 0.6 10.8 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain Hemopexin PF00045.17 001202070.1_18528001_1 - 1.8e-54 181.3 17.9 4.2e-17 61.7 0.7 4.5 4 0 0 4 4 4 4 Hemopexin Peptidase_M10 PF00413.22 001202070.1_18528001_1 - 4.8e-54 182.4 0.0 7.4e-54 181.7 0.0 1.3 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.16 001202070.1_18528001_1 - 5.3e-10 39.2 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_4 PF13583.4 001202070.1_18528001_1 - 0.0061 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.3 001202070.1_18528001_1 - 0.011 14.9 0.3 0.017 14.2 0.3 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.4 001202070.1_18528001_1 - 0.088 13.2 0.2 0.18 12.2 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Sensor PF13796.4 001202070.1_18528001_1 - 1.2 9.0 4.3 0.31 10.9 0.8 1.8 2 0 0 2 2 2 0 Putative sensor Pro_isomerase PF00160.19 079049.4_18522001_2 - 1.6e-47 161.6 0.4 2.2e-47 161.1 0.4 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.20 079049.4_18522001_2 - 6.4e-21 73.8 0.0 1.2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 079049.4_18522001_2 - 0.00023 20.8 0.0 0.00064 19.4 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.3 079049.4_18522001_2 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.4 079049.4_18522001_2 - 0.056 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PDZ PF00595.22 176201.3_18524001_2 - 4.4e-15 55.7 0.4 7.9e-15 54.9 0.4 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PH PF00169.27 176201.3_18524001_2 - 0.015 15.7 0.0 0.08 13.3 0.0 2.2 2 0 0 2 2 2 0 PH domain PDZ_2 PF13180.4 176201.3_18524001_2 - 0.072 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Voldacs PF03517.11 137393.4_18522001_1 - 9.3e-26 90.5 1.8 1.7e-25 89.6 1.8 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Pkinase PF00069.23 176203.3_18526001_2 - 3.8e-34 118.1 0.0 5.9e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 176203.3_18526001_2 - 5e-22 78.3 0.0 1.1e-21 77.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.4 176203.3_18526001_2 - 2.5e-06 26.9 0.0 4.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 176203.3_18526001_2 - 0.0016 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family eIF-3c_N PF05470.10 137398.2_18527001_1 - 2.5e-256 851.6 30.8 3.7e-254 844.4 30.8 2.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.25 137398.2_18527001_1 - 7e-15 55.3 0.0 4.4e-14 52.7 0.0 2.5 2 0 0 2 2 2 1 PCI domain DUF2779 PF11074.6 137398.2_18527001_1 - 0.51 10.7 4.7 6.9 7.0 0.0 4.3 4 1 1 5 5 5 0 Domain of unknown function(DUF2779) Claudin_2 PF13903.4 001169711.2_18524001_1 - 4e-15 55.9 4.6 4.4e-07 29.7 0.1 2.4 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.18 001169711.2_18524001_1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 2.5 3 0 0 3 3 3 2 PMP-22/EMP/MP20/Claudin family Vps54_N PF10475.7 137414.3_18528001_1 - 1.7e-105 352.4 14.8 1.7e-105 352.4 14.8 2.3 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.7 137414.3_18528001_1 - 6.4e-74 248.5 3.9 6.4e-74 248.5 3.9 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Glyco_hydro_38C PF07748.11 137414.3_18528001_1 - 0.072 12.0 0.7 0.12 11.2 0.7 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain Sec8_exocyst PF04048.12 137414.3_18528001_1 - 0.12 12.2 10.1 7.1 6.4 2.5 3.7 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain RGS PF00615.17 001299621.1_18529001_1 - 7e-33 113.3 1.5 1.2e-32 112.5 1.5 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain NAD_binding_4 PF07993.10 001169698.3_18529001_1 - 6.3e-78 261.3 0.0 8.6e-78 260.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.17 001169698.3_18529001_1 - 1.8e-33 114.5 0.4 1.5e-32 111.5 0.4 2.4 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.17 001169698.3_18529001_1 - 2.5e-07 29.8 0.0 2.7e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.19 001169698.3_18529001_1 - 1e-05 25.0 0.0 5.8e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.13 001169698.3_18529001_1 - 0.00018 20.6 0.0 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.3 001169698.3_18529001_1 - 0.00069 18.9 0.0 0.0042 16.4 0.0 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.8 001169698.3_18529001_1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.22 001169698.3_18529001_1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RRM_1 PF00076.20 057319.5_18525001_3 - 4.6e-83 272.9 6.0 4.3e-22 77.6 0.6 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.16 057319.5_18525001_3 - 3.2e-29 100.8 3.7 5.2e-28 96.9 3.4 2.7 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.4 057319.5_18525001_3 - 5.4e-10 38.8 0.0 0.0058 16.1 0.0 4.4 1 1 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 057319.5_18525001_3 - 5e-07 29.6 0.5 1.1 9.3 0.0 4.6 3 1 1 4 4 4 3 RNA recognition motif Nup35_RRM_2 PF14605.4 057319.5_18525001_3 - 1.5e-05 24.7 2.5 1.4 8.8 0.1 4.7 5 0 0 5 5 5 3 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.3 057319.5_18525001_3 - 0.00096 18.8 0.0 0.86 9.4 0.0 3.4 4 0 0 4 4 4 1 Occluded RNA-recognition motif OB_RNB PF08206.9 057319.5_18525001_3 - 0.019 14.5 3.1 6.2 6.5 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain SET_assoc PF11767.6 057319.5_18525001_3 - 0.025 14.1 0.1 15 5.2 0.0 3.9 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated PHM7_cyt PF14703.4 057319.5_18525001_3 - 0.031 14.4 1.4 21 5.1 0.6 4.7 3 1 2 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Pkinase PF00069.23 057878.4_18523001_3 - 9.8e-70 234.8 0.0 1.4e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 057878.4_18523001_3 - 2.9e-33 115.1 0.0 5.1e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 057878.4_18523001_3 - 0.0066 15.7 0.2 0.041 13.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.20 057878.4_18523001_3 - 0.035 13.6 1.5 0.15 11.6 1.5 1.9 1 1 0 1 1 1 0 RIO1 family Shugoshin_N PF07558.9 001299776.1_18524001_3 - 6e-10 38.7 0.6 3.3e-09 36.3 0.5 2.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.9 001299776.1_18524001_3 - 5.3e-07 29.2 2.2 5.3e-07 29.2 2.2 3.1 3 0 0 3 3 3 1 Shugoshin C terminus Integrin_alpha2 PF08441.10 137964.2_18527001_1 - 3.3e-21 75.6 0.1 8.9e-21 74.2 0.1 1.7 1 1 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 137964.2_18527001_1 - 1.2e-20 73.2 24.6 5e-08 32.8 1.5 4.0 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.4 137964.2_18527001_1 - 2.9e-12 46.8 2.2 2.4e-09 37.5 0.9 2.7 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.4 137964.2_18527001_1 - 0.00018 21.5 15.4 0.1 12.7 1.4 4.7 6 0 0 6 6 6 3 FG-GAP repeat N_Asn_amidohyd PF14736.4 001169728.2_18524001_1 - 5.6e-109 363.3 0.0 7.1e-109 363.0 0.0 1.1 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase FKBP_C PF00254.26 001299652.1_18524001_3 - 1.5e-15 57.1 0.0 3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.26 001299652.1_18524001_3 - 2.9e-08 33.1 0.5 0.34 10.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.15 001299652.1_18524001_3 - 5.2e-07 29.2 0.5 0.045 13.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.4 001299652.1_18524001_3 - 2.5e-05 24.0 0.1 0.045 13.9 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat NARP1 PF12569.6 001299652.1_18524001_3 - 3.5e-05 22.8 0.8 6e-05 22.0 0.8 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.4 001299652.1_18524001_3 - 4.6e-05 23.8 0.5 0.065 14.0 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.4 001299652.1_18524001_3 - 7.7e-05 23.0 0.9 0.014 15.8 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.4 001299652.1_18524001_3 - 0.0003 20.8 0.4 0.016 15.4 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.4 001299652.1_18524001_3 - 0.0015 18.3 0.6 6 7.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.4 001299652.1_18524001_3 - 0.0029 18.1 0.1 0.37 11.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001299652.1_18524001_3 - 0.0042 17.0 0.6 0.027 14.4 0.2 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.4 001299652.1_18524001_3 - 0.011 15.9 0.5 4.9 7.4 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.4 001299652.1_18524001_3 - 0.021 14.3 0.1 4 7.1 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.4 001299652.1_18524001_3 - 0.052 14.1 2.1 0.12 13.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.4 001299652.1_18524001_3 - 0.096 12.7 0.5 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.29 001259554.2_18524001_2 - 3.3e-26 91.1 4.0 5.5e-26 90.3 4.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.16 001259554.2_18524001_2 - 3.2e-25 88.8 0.0 4.5e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.17 001259554.2_18524001_2 - 5.1e-09 36.3 18.2 1.2e-08 35.1 18.2 1.7 1 0 0 1 1 1 1 DnaJ central domain DUF498 PF04430.12 137996.4_18522001_2 - 9.1e-29 99.6 0.0 1.2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Death PF00531.20 133166.4_18523001_3 - 3e-08 33.6 0.3 6.9e-08 32.4 0.3 1.5 1 0 0 1 1 1 1 Death domain Death PF00531.20 001299643.1_18524001_3 - 3.8e-08 33.2 0.3 8.6e-08 32.1 0.3 1.5 1 0 0 1 1 1 1 Death domain AA_permease PF00324.19 001299864.1_18529001_2 - 3.6e-63 213.7 38.0 7.2e-41 140.1 6.5 2.5 3 0 0 3 3 3 2 Amino acid permease SLC12 PF03522.13 001299864.1_18529001_2 - 2.5e-50 171.6 8.5 1.1e-17 64.1 0.1 3.3 1 1 1 3 3 3 3 Solute carrier family 12 AA_permease PF00324.19 001299865.1_18528001_3 - 3e-63 213.9 38.5 5.6e-41 140.5 6.5 2.5 3 0 0 3 3 3 2 Amino acid permease SLC12 PF03522.13 001299865.1_18528001_3 - 1.5e-50 172.3 8.5 9.1e-18 64.3 0.1 3.3 1 1 1 3 3 3 3 Solute carrier family 12 Nucleopor_Nup85 PF07575.11 137456.3_18525001_1 - 4.8e-163 543.6 11.6 7.1e-163 543.1 10.5 1.6 2 0 0 2 2 2 1 Nup85 Nucleoporin BTB PF00651.29 001299635.1_18522001_2 - 1.1e-27 96.3 0.1 1.6e-27 95.8 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.29 001169715.2_18523001_3 - 1.1e-27 96.3 0.1 1.9e-27 95.5 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain ULD PF16534.3 057894.4_18529001_3 - 7.7e-39 132.0 0.1 7.7e-39 132.0 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-like oligomerisation domain of SATB Homeobox PF00046.27 057894.4_18529001_3 - 2.2e-14 52.8 8.9 4.4e-07 29.5 1.7 2.6 2 0 0 2 2 2 2 Homeobox domain MMR1 PF08505.8 057894.4_18529001_3 - 0.0035 17.5 12.9 0.0035 17.5 12.9 2.9 3 0 0 3 3 3 1 Mitochondrial Myo2 receptor-related protein SH3_1 PF00018.26 165998.2_18526001_3 - 2.2e-33 113.5 0.9 2.5e-16 58.9 0.1 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.4 165998.2_18526001_3 - 2.3e-28 97.7 0.1 2.7e-15 55.8 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.22 165998.2_18526001_3 - 4e-22 77.9 0.0 7.2e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_2 PF07653.15 165998.2_18526001_3 - 1.2e-21 76.0 0.0 2.7e-12 46.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH2_2 PF14633.4 165998.2_18526001_3 - 0.0021 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Wtap PF17098.3 001259377.2_18525001_2 - 6e-61 204.8 13.6 6e-61 204.8 13.6 2.9 4 0 0 4 4 4 2 WTAP/Mum2p family Bacillus_HBL PF05791.9 001259377.2_18525001_2 - 0.0022 17.6 13.9 0.0045 16.6 5.6 2.5 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) TBPIP PF07106.11 001259377.2_18525001_2 - 0.0028 17.3 8.7 0.0028 17.3 8.7 3.9 2 1 1 4 4 4 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.7 001259377.2_18525001_2 - 0.0043 16.9 8.4 0.0043 16.9 8.4 3.1 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.11 001259377.2_18525001_2 - 0.02 15.4 1.8 0.02 15.4 1.8 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF972) UvsY PF11056.6 001259377.2_18525001_2 - 0.11 12.8 1.8 2.8 8.1 0.4 2.5 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY DUF2312 PF10073.7 001259377.2_18525001_2 - 0.24 10.9 0.0 0.24 10.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF1664 PF07889.10 001259377.2_18525001_2 - 0.33 10.8 5.4 0.4 10.5 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.10 001259377.2_18525001_2 - 1.9 8.4 8.9 1.5 8.7 2.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus QVR PF17064.3 166011.3_18526001_1 - 0.24 11.1 5.0 0.55 9.9 5.0 1.5 1 1 0 1 1 1 0 Sleepless protein Glyco_transf_21 PF13506.4 137792.3_18527001_3 - 2.2e-52 176.9 0.0 3e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.4 137792.3_18527001_3 - 1.1e-16 61.3 0.0 1.7e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.4 137792.3_18527001_3 - 3.7e-06 26.8 2.9 3.7e-06 26.8 2.9 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Ras PF00071.20 078963.3_18528001_2 - 3.9e-61 205.2 1.7 5.2e-61 204.8 1.7 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 078963.3_18528001_2 - 5.2e-32 110.5 1.0 8.1e-32 109.8 1.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 078963.3_18528001_2 - 7.7e-13 48.1 0.3 1.1e-12 47.6 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 078963.3_18528001_2 - 0.0023 17.3 0.0 0.0048 16.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 078963.3_18528001_2 - 0.0055 16.0 0.2 0.008 15.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 078963.3_18528001_2 - 0.0083 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 078963.3_18528001_2 - 0.01 15.3 0.2 0.018 14.4 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.16 078963.3_18528001_2 - 0.018 14.4 0.0 0.14 11.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B WD40 PF00400.30 057609.6_18525001_3 - 1.1e-48 162.0 19.3 1.2e-10 41.6 0.2 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.13 057609.6_18525001_3 - 1.4e-31 109.3 3.5 2.8e-31 108.4 3.5 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.5 057609.6_18525001_3 - 4.2e-12 46.1 0.4 0.0019 18.3 0.0 5.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 057609.6_18525001_3 - 1.5e-07 30.6 1.3 0.05 12.4 0.0 4.2 2 1 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.3 057609.6_18525001_3 - 0.0028 16.9 0.1 0.18 10.9 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.6 057609.6_18525001_3 - 0.0081 14.7 11.7 0.093 11.2 0.1 4.5 1 1 4 6 6 6 2 Nucleoporin Nup120/160 DUF4471 PF14740.4 057609.6_18525001_3 - 0.033 13.2 0.7 0.072 12.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) TSGP1 PF07771.9 057609.6_18525001_3 - 0.62 10.1 3.3 1.1 9.2 3.3 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 Arf PF00025.19 137577.3_18522001_3 - 1.2e-42 145.2 0.1 1.4e-42 144.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.20 137577.3_18522001_3 - 3.6e-12 46.0 0.0 4.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.8 137577.3_18522001_3 - 5.4e-09 35.6 0.1 7.4e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.18 137577.3_18522001_3 - 2.2e-07 30.2 2.3 0.0064 15.6 0.4 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.11 137577.3_18522001_3 - 9.1e-07 29.0 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.21 137577.3_18522001_3 - 2e-06 27.7 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 137577.3_18522001_3 - 2e-05 23.9 0.3 2.5e-05 23.6 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.9 137577.3_18522001_3 - 0.0036 16.4 0.1 0.0059 15.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_15 PF13175.4 137577.3_18522001_3 - 0.014 14.9 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.25 137577.3_18522001_3 - 0.018 14.4 0.1 0.059 12.8 0.1 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.4 137577.3_18522001_3 - 0.042 14.1 0.0 0.1 12.8 0.0 1.5 1 1 1 2 2 2 0 AAA ATPase domain FeoB_N PF02421.16 137577.3_18522001_3 - 0.087 12.2 0.2 0.17 11.3 0.2 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.4 137577.3_18522001_3 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_M3 PF01432.18 136339.3_18525001_3 - 3.7e-122 408.7 0.0 4.9e-122 408.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Ig_3 PF13927.4 001259240.1_18529001_1 - 4.6e-111 363.5 4.9 2.2e-13 50.5 0.0 11.1 11 0 0 11 11 11 10 Immunoglobulin domain I-set PF07679.14 001259240.1_18529001_1 - 4.7e-110 359.8 4.1 1.5e-14 53.6 0.0 11.5 11 0 0 11 11 11 9 Immunoglobulin I-set domain fn3 PF00041.19 001259240.1_18529001_1 - 1.2e-74 246.5 24.5 3.5e-16 59.2 0.8 6.7 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.4 001259240.1_18529001_1 - 6.5e-72 237.8 0.0 6.4e-08 32.7 0.0 10.7 10 0 0 10 10 10 9 Immunoglobulin domain ig PF00047.23 001259240.1_18529001_1 - 1.2e-67 224.0 0.0 1.1e-08 34.9 0.0 10.7 10 0 0 10 10 10 9 Immunoglobulin domain Dscam_C PF12355.6 001259240.1_18529001_1 - 1.2e-62 209.9 22.0 4.7e-57 191.9 14.6 2.9 2 0 0 2 2 2 2 Down syndrome cell adhesion molecule C terminal V-set PF07686.15 001259240.1_18529001_1 - 4.2e-28 97.5 7.5 0.0038 17.2 0.1 12.9 10 5 1 11 11 11 7 Immunoglobulin V-set domain C2-set_2 PF08205.10 001259240.1_18529001_1 - 5.7e-20 71.1 0.6 0.0038 17.1 0.0 8.9 8 0 0 8 8 8 5 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001259240.1_18529001_1 - 8.7e-16 58.0 1.2 0.037 14.3 0.0 9.6 10 1 0 10 10 9 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001259240.1_18529001_1 - 1.6e-10 41.3 21.2 0.0068 16.8 0.3 6.2 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.3 001259240.1_18529001_1 - 1.8e-07 31.3 3.4 0.027 14.7 0.0 7.8 8 1 0 8 8 7 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.3 001259240.1_18529001_1 - 2e-05 24.4 0.6 8.3 6.4 0.0 6.3 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 001259240.1_18529001_1 - 0.005 16.9 1.2 11 6.1 0.0 5.3 7 0 0 7 7 6 0 Natural killer cell receptor 2B4 C2-set PF05790.13 001259240.1_18529001_1 - 0.024 14.7 0.0 42 4.3 0.0 4.8 5 0 0 5 5 5 0 Immunoglobulin C2-set domain ASH PF15780.3 001259240.1_18529001_1 - 0.11 12.6 2.8 2.3 8.3 0.3 3.1 3 0 0 3 3 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF3697 PF12478.6 001259271.2_18529001_1 - 1.9e-20 72.5 0.2 4.8e-20 71.2 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 DUF1296 PF06972.9 001259271.2_18529001_1 - 0.017 15.1 0.1 0.035 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) DpnD-PcfM PF14207.4 001259271.2_18529001_1 - 0.25 11.1 0.4 0.49 10.2 0.4 1.4 1 0 0 1 1 1 0 DpnD/PcfM-like protein GAIN PF16489.3 001259275.2_18528001_1 - 1.8e-49 167.9 2.0 1.8e-49 167.9 2.0 1.7 2 0 0 2 2 2 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.16 001259275.2_18528001_1 - 2.9e-20 72.3 0.6 8.6e-20 70.8 0.6 1.9 1 0 0 1 1 1 1 Galactose binding lectin domain GPS PF01825.19 001259275.2_18528001_1 - 3.6e-14 53.0 6.8 7.9e-14 51.9 6.8 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.20 001259275.2_18528001_1 - 0.0099 16.0 0.1 0.025 14.7 0.1 1.7 1 0 0 1 1 1 1 Hormone receptor domain Olfactory_mark PF06554.10 001259275.2_18528001_1 - 0.069 12.8 0.6 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Olfactory marker protein RskA PF10099.7 001259275.2_18528001_1 - 0.094 12.9 9.6 0.37 10.9 9.5 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF1049 PF06305.9 001259314.1_18521001_1 - 0.034 13.8 0.1 5.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) UPF0154 PF03672.11 001259314.1_18521001_1 - 5.6 6.9 6.8 13 5.8 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) 7TMR-DISM_7TM PF07695.9 001259341.2_18522001_2 - 0.00082 19.2 13.0 0.001 18.9 13.0 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling VWA_N PF08399.9 001259375.2_18529001_3 - 2e-37 128.3 0.9 4e-37 127.3 0.1 1.9 2 0 0 2 2 2 1 VWA N-terminal VGCC_alpha2 PF08473.9 001259375.2_18529001_3 - 4.6e-24 84.8 0.8 8.7e-23 80.7 0.1 2.4 2 0 0 2 2 2 1 Neuronal voltage-dependent calcium channel alpha 2acd dCache_1 PF02743.16 001259375.2_18529001_3 - 3.5e-18 66.2 1.8 6.5e-12 45.6 0.1 2.9 3 0 0 3 3 3 2 Cache domain VWA PF00092.26 001259375.2_18529001_3 - 1.7e-12 47.8 0.0 2.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.4 001259375.2_18529001_3 - 7.3e-12 45.3 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.4 001259375.2_18529001_3 - 1.4e-11 44.9 0.0 2.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_2 PF08269.9 001259375.2_18529001_3 - 0.02 14.0 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Cache domain Spectrin PF00435.19 001259383.1_18529001_2 - 5.4e-220 714.5 301.9 1.1e-15 57.8 7.1 40.9 38 3 3 41 41 41 36 Spectrin repeat GAS2 PF02187.15 001259383.1_18529001_2 - 2.8e-32 110.5 0.7 9.8e-32 108.7 0.7 2.1 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.29 001259383.1_18529001_2 - 2.8e-22 78.8 0.7 5.3e-21 74.7 0.0 3.8 3 0 0 3 3 3 1 Calponin homology (CH) domain EF-hand_6 PF13405.4 001259383.1_18529001_2 - 7.2e-07 28.5 0.5 0.016 14.9 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain ATG16 PF08614.9 001259383.1_18529001_2 - 5.7e-06 26.5 2.6 5.7e-06 26.5 2.6 21.1 16 6 7 23 23 13 2 Autophagy protein 16 (ATG16) EF-hand_1 PF00036.30 001259383.1_18529001_2 - 7.1e-06 25.1 0.6 0.055 12.9 0.0 3.3 2 0 0 2 2 2 2 EF hand Plectin PF00681.18 001259383.1_18529001_2 - 3.5e-05 23.4 0.9 0.022 14.5 0.1 2.8 1 1 1 2 2 2 2 Plectin repeat EF-hand_7 PF13499.4 001259383.1_18529001_2 - 3.7e-05 24.0 0.3 3.7e-05 24.0 0.3 5.2 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_8 PF13833.4 001259383.1_18529001_2 - 0.00028 20.4 0.7 0.23 11.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair Med9 PF07544.11 001259383.1_18529001_2 - 0.0071 16.3 0.2 0.0071 16.3 0.2 14.5 15 0 0 15 15 12 2 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.16 001259383.1_18529001_2 - 0.015 14.5 0.1 0.015 14.5 0.1 19.3 14 6 6 22 22 22 0 CorA-like Mg2+ transporter protein CAMSAP_CH PF11971.6 001259383.1_18529001_2 - 0.016 14.9 0.0 0.061 13.0 0.0 2.0 1 0 0 1 1 1 0 CAMSAP CH domain DUF630 PF04783.10 001259383.1_18529001_2 - 0.072 13.2 0.6 2.9 8.1 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF630) EF-hand_5 PF13202.4 001259383.1_18529001_2 - 0.075 12.5 2.7 11 5.6 0.1 3.1 2 0 0 2 2 2 0 EF hand HD_5 PF13487.4 001259383.1_18529001_2 - 0.15 12.2 6.7 1.2 9.3 0.1 5.0 5 0 0 5 5 4 0 HD domain DUF573 PF04504.12 001259383.1_18529001_2 - 0.17 12.4 19.4 3.2 8.3 0.6 9.5 9 0 0 9 9 8 0 Protein of unknown function, DUF573 HEPN PF05168.12 001259383.1_18529001_2 - 4 7.5 11.6 1.7 8.7 0.3 6.2 5 0 0 5 5 5 0 HEPN domain DUF1940 PF09155.8 001259383.1_18529001_2 - 5.2 7.0 7.6 1.7 8.6 0.2 3.9 3 0 0 3 3 2 0 Domain of unknown function (DUF1940) RNA_GG_bind PF10258.7 165644.3_18524001_1 - 6.2e-31 106.1 0.4 1.1e-30 105.3 0.4 1.4 1 0 0 1 1 1 1 PHAX RNA-binding domain Nucleos_tra2_C PF07662.11 206060.3_18525001_3 - 1.4e-66 224.3 6.2 1.4e-66 224.3 6.2 2.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.18 206060.3_18525001_3 - 2e-24 85.9 1.2 2e-24 85.9 1.2 4.0 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.12 206060.3_18525001_3 - 3.9e-08 33.4 21.3 2.2e-07 31.0 9.0 3.5 2 1 0 2 2 2 2 Nucleoside recognition DUF912 PF06024.10 206060.3_18525001_3 - 5 7.3 8.8 4.2 7.6 0.0 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-C2H2 PF00096.24 001259402.2_18529001_3 - 2.2e-06 27.7 28.2 0.022 15.1 0.8 6.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001259402.2_18529001_3 - 0.0004 20.6 8.1 0.001 19.3 1.6 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.4 001259402.2_18529001_3 - 0.022 14.4 35.7 0.033 13.8 0.1 5.0 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.4 001259402.2_18529001_3 - 0.38 11.6 36.6 1.3 9.9 1.0 6.8 6 0 0 6 6 6 0 C2H2-type zinc finger RabGAP-TBC PF00566.16 001274032.2_18526001_2 - 3.2e-52 177.2 4.2 4.9e-52 176.6 4.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1803 PF08820.8 001274032.2_18526001_2 - 0.022 14.7 0.3 0.074 12.9 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) zf-C2H2 PF00096.24 001259405.2_18529001_3 - 8.7e-07 28.9 28.2 0.018 15.4 0.8 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001259405.2_18529001_3 - 0.0002 21.5 8.1 0.00083 19.6 1.6 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 001259405.2_18529001_3 - 0.0015 19.0 29.2 1.1 10.2 1.0 6.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_5 PF13909.4 001259405.2_18529001_3 - 0.023 14.3 37.0 0.026 14.2 0.1 5.0 5 0 0 5 5 5 0 C2H2-type zinc-finger domain WBP-1 PF11669.6 001259414.2_18522001_2 - 0.0068 16.9 0.1 0.04 14.4 0.1 2.2 1 1 0 1 1 1 1 WW domain-binding protein 1 DUF4834 PF16118.3 001259414.2_18522001_2 - 0.036 14.9 0.0 0.057 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) HemY_N PF07219.11 001259414.2_18522001_2 - 0.17 12.0 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Asp_Arg_Hydrox PF05118.13 001259428.2_18526001_2 - 3.7e-54 182.7 1.1 1.2e-53 181.0 0.2 2.2 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_16 PF13432.4 001259428.2_18526001_2 - 0.0028 18.2 6.8 0.057 14.0 1.6 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.4 001259428.2_18526001_2 - 0.0038 17.3 10.9 0.19 11.9 2.2 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat DnaJ PF00226.29 001259435.2_18525001_2 - 9.5e-27 92.8 3.1 1.9e-26 91.8 3.1 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.4 001259435.2_18525001_2 - 0.094 12.5 0.1 0.3 10.9 0.1 1.8 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF2986 PF11661.6 137186.3_18521001_2 - 0.52 10.7 2.1 21 5.6 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2986) DUF1108 PF06531.9 137186.3_18521001_2 - 2.4 8.3 7.3 45 4.2 7.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1108) CDT1 PF08839.9 001299522.1_18526001_3 - 8.5e-55 185.6 9.7 5.9e-54 182.8 4.0 3.3 3 0 0 3 3 3 2 DNA replication factor CDT1 like CDT1_C PF16679.3 001299522.1_18526001_3 - 4.7e-24 84.5 1.7 4.7e-24 84.5 1.7 4.1 4 1 1 5 5 5 1 DNA replication factor Cdt1 C-terminal domain OGFr_III PF04680.11 001299522.1_18526001_3 - 0.18 12.3 3.9 0.55 10.8 3.9 1.9 1 0 0 1 1 1 0 Opioid growth factor receptor repeat Trypsin PF00089.24 001299293.1_18524001_1 - 6.7e-64 215.6 0.1 8.9e-64 215.2 0.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001299293.1_18524001_1 - 1.3e-06 29.2 0.4 3.1e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF316 PF03761.13 001299293.1_18524001_1 - 2.9e-05 23.6 0.0 0.24 10.8 0.0 2.8 2 1 1 3 3 3 2 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.9 001299293.1_18524001_1 - 0.0036 17.5 0.1 0.0097 16.2 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) BESS PF02944.18 001299293.1_18524001_2 - 0.07 12.8 0.2 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 BESS motif Pkinase PF00069.23 137190.4_18529001_2 - 6.6e-42 143.6 0.0 5.2e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.15 137190.4_18529001_2 - 2.6e-11 43.2 0.0 1.9e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase ASC PF00858.22 001347816.1_18524001_1 - 5e-84 282.5 12.1 5.8e-84 282.3 12.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Me-amine-dh_H PF06433.9 001347816.1_18524001_1 - 0.14 10.9 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) DUF912 PF06024.10 001347816.1_18524001_1 - 0.16 12.1 1.0 11 6.2 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RskA PF10099.7 137195.3_18525001_1 - 0.46 10.6 17.3 8.3 6.5 0.1 2.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Ldl_recept_a PF00057.16 137195.3_18525001_1 - 9.2 6.4 7.1 18 5.5 7.1 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A RskA PF10099.7 001299530.1_18526001_1 - 0.86 9.7 17.6 10 6.3 0.1 2.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA FlxA PF14282.4 001259552.1_18521001_1 - 0.0023 17.8 1.4 0.0031 17.4 1.4 1.2 1 0 0 1 1 1 1 FlxA-like protein DivIC PF04977.13 001259552.1_18521001_1 - 0.0086 15.7 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.13 001259552.1_18521001_1 - 0.017 15.1 0.3 0.017 15.1 0.3 1.6 2 0 0 2 2 2 0 Basic region leucine zipper FliS PF02561.12 001259552.1_18521001_1 - 0.043 14.0 1.9 0.055 13.6 1.9 1.1 1 0 0 1 1 1 0 Flagellar protein FliS NKAIN PF05640.12 001259577.2_18529001_3 - 8.7e-96 318.8 4.6 1.2e-95 318.4 4.6 1.2 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein BIR PF00653.19 176182.2_18524001_3 - 2.7e-55 184.8 15.0 1.6e-20 73.4 0.3 4.2 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.4 176182.2_18524001_3 - 1.7e-13 50.1 5.4 1.7e-13 50.1 5.4 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 176182.2_18524001_3 - 8.9e-06 25.3 9.1 3.6e-05 23.4 7.4 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC PF07967.11 176182.2_18524001_3 - 0.0062 16.4 0.3 0.09 12.6 0.1 2.4 2 0 0 2 2 2 1 C3HC zinc finger-like RNA_pol_N PF01194.15 176182.2_18524001_3 - 0.074 13.2 0.2 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit zf-RING_5 PF14634.4 176182.2_18524001_3 - 6.5 6.7 16.9 0.037 13.9 6.9 2.5 3 0 0 3 3 3 0 zinc-RING finger domain Thioredoxin PF00085.18 137221.3_18523001_3 - 0.00033 20.4 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin ARL6IP6 PF15062.4 136876.3_18523001_1 - 2.2e-43 146.2 0.1 4.8e-43 145.1 0.1 1.6 1 0 0 1 1 1 1 Haemopoietic lineage transmembrane helix Cytotoxic PF09000.8 136876.3_18523001_3 - 0.24 11.6 0.9 0.52 10.6 0.9 1.5 1 0 0 1 1 1 0 Cytotoxic Ribosomal_S19 PF00203.19 137292.4_18522001_1 - 5.9e-34 115.7 0.3 9.4e-34 115.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_S19 PF00203.19 166183.3_18522001_1 - 8.2e-34 115.2 0.3 1.3e-33 114.6 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 MFS_1 PF07690.14 137232.4_18524001_2 - 5e-33 114.4 41.5 3.6e-29 101.7 21.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily COesterase PF00135.26 001299547.1_18524001_1 - 4.5e-124 415.0 0.0 5.8e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001299547.1_18524001_1 - 2.8e-08 33.8 0.3 1e-07 31.9 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.18 001299547.1_18524001_1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.19 001299547.1_18524001_1 - 0.027 13.8 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family zf-C2H2_10 PF16588.3 001299547.1_18524001_1 - 0.13 11.9 3.3 0.22 11.2 3.3 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger MFS_1 PF07690.14 166146.2_18527001_1 - 3.4e-39 134.6 23.2 5.6e-39 133.9 23.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.18 166146.2_18527001_1 - 9.5e-15 53.8 13.0 9e-08 30.7 0.2 4.2 1 1 3 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.22 166146.2_18527001_1 - 1.8e-13 50.0 3.7 1.8e-13 50.0 3.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.12 166146.2_18527001_1 - 0.12 11.5 15.9 0.033 13.4 12.5 1.8 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.14 080084.3_18527001_1 - 5.3e-39 134.0 25.4 8.8e-39 133.3 25.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.18 080084.3_18527001_1 - 5.8e-13 47.9 11.6 9.2e-08 30.7 0.1 4.0 1 1 3 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.22 080084.3_18527001_1 - 1.7e-10 40.2 18.0 2.6e-09 36.3 18.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.12 080084.3_18527001_1 - 0.19 10.9 16.5 0.056 12.6 13.1 1.7 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB AIRS_C PF02769.20 166045.2_18524001_2 - 1.5e-30 106.3 0.1 2.2e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.22 166045.2_18524001_2 - 1.2e-09 38.6 1.0 2.2e-09 37.7 0.3 1.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain p450 PF00067.20 136952.3_18524001_3 - 8.2e-59 199.4 0.0 1e-58 199.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRR_8 PF13855.4 079073.3_18529001_1 - 1.2e-92 303.5 84.0 5.1e-15 54.8 2.3 13.9 5 2 8 15 15 15 13 Leucine rich repeat LRR_4 PF12799.5 079073.3_18529001_1 - 5.9e-38 128.0 93.3 8.2e-05 22.7 0.5 16.1 10 4 9 20 20 20 16 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 079073.3_18529001_1 - 1.1e-37 128.7 4.3 1.4e-10 41.1 0.3 6.4 3 1 5 8 8 8 6 Leucine rich repeats (6 copies) LRR_9 PF14580.4 079073.3_18529001_1 - 2.8e-16 59.4 29.6 0.0002 20.8 4.4 6.9 4 1 3 7 7 7 6 Leucine-rich repeat TIR PF01582.18 079073.3_18529001_1 - 4.2e-06 26.5 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 079073.3_18529001_1 - 5.5e-05 22.9 75.5 3.4 8.4 0.7 19.9 22 3 0 22 22 22 4 Leucine Rich Repeat TIR_2 PF13676.4 079073.3_18529001_1 - 0.0003 20.9 0.1 0.0006 20.0 0.1 1.4 1 0 0 1 1 1 1 TIR domain Cation_efflux PF01545.19 136962.3_18526001_3 - 7.4e-28 97.5 8.3 1.1e-27 97.0 8.3 1.2 1 0 0 1 1 1 1 Cation efflux family RhaT PF06379.10 136962.3_18526001_3 - 0.039 13.0 3.2 0.062 12.3 3.2 1.3 1 0 0 1 1 1 0 L-rhamnose-proton symport protein (RhaT) LNS2 PF08235.11 001201952.1_18527001_2 - 7.4e-103 342.7 0.0 1.2e-102 342.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_mid PF16876.3 001201952.1_18527001_2 - 6.1e-34 116.1 0.0 6.1e-34 116.1 0.0 2.8 3 0 0 3 3 3 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Lipin_N PF04571.12 001201952.1_18527001_2 - 2.3e-11 43.4 0.0 4.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region WRNPLPNID PF15017.4 001201952.1_18527001_2 - 0.00064 20.4 4.9 0.00071 20.3 0.1 3.5 2 0 0 2 2 2 1 Putative WW-binding domain and destruction box Fer4 PF00037.25 165583.2_18523001_1 - 2.1 8.2 7.4 0.93 9.3 1.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain zf-CXXC PF02008.18 165583.2_18523001_1 - 5.3 7.0 11.6 15 5.5 3.3 2.8 2 0 0 2 2 2 0 CXXC zinc finger domain WD40 PF00400.30 165583.2_18523001_2 - 1e-16 60.8 13.9 0.00014 22.4 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 165583.2_18523001_2 - 9e-06 25.8 1.5 0.096 12.9 0.0 4.0 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 165583.2_18523001_2 - 0.015 14.1 0.3 3.7 6.3 0.0 3.2 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PCI PF01399.25 001169609.2_18523001_3 - 9.8e-19 67.7 0.2 9.8e-19 67.7 0.2 2.2 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.4 001169609.2_18523001_3 - 0.015 15.7 0.1 0.81 10.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.4 001169609.2_18523001_3 - 0.033 14.1 2.2 2.5 8.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat GRP PF07172.9 001144149.2_18529001_3 - 0.2 12.2 4.2 0.66 10.6 4.2 1.9 1 0 0 1 1 1 0 Glycine rich protein family NAC PF01849.16 165950.2_18522001_1 - 6e-24 83.7 1.2 9.7e-24 83.0 0.5 1.7 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.4 165950.2_18522001_1 - 0.058 13.1 0.2 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 UBA-like domain Pkinase PF00069.23 136973.2_18523001_2 - 2e-40 138.7 0.0 3.2e-40 138.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 136973.2_18523001_2 - 1.9e-29 102.6 0.1 1.9e-28 99.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.9 136973.2_18523001_2 - 0.00049 19.1 0.0 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Cytochrom_B561 PF03188.14 165936.3_18524001_3 - 2.2e-40 137.8 15.6 2.8e-39 134.3 13.8 2.3 2 0 0 2 2 2 2 Eukaryotic cytochrome b561 Sin3a_C PF16879.3 165916.3_18529001_2 - 4.5e-58 197.1 0.2 4.5e-58 197.1 0.2 2.9 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.19 165916.3_18529001_2 - 6.1e-42 141.4 13.6 5.2e-17 61.6 1.9 4.2 5 0 0 5 5 5 3 Paired amphipathic helix repeat Sin3_corepress PF08295.10 165916.3_18529001_2 - 5.1e-41 138.6 0.4 2.3e-40 136.5 0.2 2.3 2 0 0 2 2 2 1 Sin3 family co-repressor She9_MDM33 PF05546.9 001299420.1_18525001_3 - 2.5 7.7 17.7 4.9 6.8 2.4 2.5 2 0 0 2 2 2 0 She9 / Mdm33 family DUF2433 PF10360.7 001299420.1_18525001_3 - 3.1 7.8 9.5 12 5.9 3.5 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2433) IncA PF04156.12 001299420.1_18525001_3 - 3.9 7.1 24.1 3.3 7.3 6.6 2.8 2 0 0 2 2 2 0 IncA protein Aida_N PF08910.8 001299420.1_18525001_3 - 6 7.2 7.6 1.7 8.9 2.3 2.9 2 1 1 3 3 3 0 Aida N-terminus Pkinase PF00069.23 001273984.1_18527001_3 - 7.8e-10 38.4 0.1 1.2e-05 24.7 0.2 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.15 001273984.1_18527001_3 - 9e-05 21.7 0.0 0.018 14.2 0.1 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.4 001273984.1_18527001_3 - 0.02 14.1 0.1 0.041 13.0 0.1 1.4 1 0 0 1 1 1 0 Kinase-like MIF4G PF02854.17 206145.3_18526001_1 - 1.4e-10 41.0 1.8 3.1e-10 39.9 1.8 1.6 1 0 0 1 1 1 1 MIF4G domain Pkinase_Tyr PF07714.15 078981.3_18529001_3 - 1.6e-62 211.0 0.0 4.5e-61 206.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Ig_3 PF13927.4 078981.3_18529001_3 - 3.2e-57 190.9 4.1 2.4e-13 50.4 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.14 078981.3_18529001_3 - 2.6e-56 187.5 0.1 3.2e-15 55.8 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.4 078981.3_18529001_3 - 3.7e-40 136.0 0.4 4.6e-09 36.4 0.1 5.9 5 1 0 5 5 5 5 Immunoglobulin domain Pkinase PF00069.23 078981.3_18529001_3 - 3.1e-32 111.8 0.0 2.7e-31 108.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain ig PF00047.23 078981.3_18529001_3 - 2.7e-31 107.5 1.3 3.5e-07 30.2 0.1 6.0 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.15 078981.3_18529001_3 - 2.6e-17 62.8 3.0 7.1e-06 26.0 0.0 7.2 5 3 1 6 6 6 3 Immunoglobulin V-set domain C2-set_2 PF08205.10 078981.3_18529001_3 - 6.9e-10 38.7 1.8 0.24 11.4 0.1 6.0 5 1 1 6 6 6 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.3 078981.3_18529001_3 - 1.2e-08 34.8 0.4 1.3 9.0 0.0 5.0 5 0 0 5 5 5 3 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.9 078981.3_18529001_3 - 0.00025 20.9 0.6 0.042 13.7 0.0 3.3 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain ATP-synt_C PF00137.19 137325.2_18522001_2 - 3.3e-33 113.7 34.9 4e-20 71.8 14.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TctB PF07331.9 137325.2_18522001_2 - 5 7.3 21.5 21 5.2 21.5 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family MIP PF00230.18 001273963.1_18523001_1 - 1.9e-61 207.6 14.3 2.9e-61 206.9 14.3 1.3 1 0 0 1 1 1 1 Major intrinsic protein Rep_N PF08724.8 001273963.1_18523001_2 - 0.043 13.4 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 Rep protein catalytic domain like Scramblase PF03803.13 001273955.2_18522001_3 - 4.7e-22 78.2 0.0 7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Scramblase ATE_C PF04377.13 001274172.1_18524001_1 - 1e-50 171.7 0.3 1.8e-50 170.9 0.3 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.11 001274172.1_18524001_1 - 2.6e-21 75.6 12.7 8.2e-21 74.1 12.7 1.9 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus RRM_5 PF13893.4 166369.5_18524001_2 - 9.6e-51 170.5 0.0 3.1e-50 168.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 166369.5_18524001_2 - 7.1e-06 25.6 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PNRC PF15365.4 166369.5_18524001_2 - 0.49 10.9 5.1 0.55 10.7 0.2 2.6 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Carb_anhydrase PF00194.19 137681.3_18523001_2 - 6.5e-57 192.9 0.0 7.8e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1899 PF08953.9 001273813.1_18526001_3 - 2.5e-34 116.8 0.2 2.5e-34 116.8 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.3 001273813.1_18526001_3 - 6.2e-20 70.7 0.0 1.1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.30 001273813.1_18526001_3 - 2.7e-11 43.7 7.7 0.00019 22.0 0.7 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001273813.1_18526001_3 - 8.9e-06 25.8 0.3 0.041 14.1 0.2 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001273813.1_18526001_3 - 0.047 12.5 0.0 0.45 9.3 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Serpin PF00079.18 206039.3_18524001_2 - 2.7e-111 372.3 2.1 3.4e-111 372.0 2.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) SNF2_N PF00176.21 001299747.1_18529001_1 - 6.5e-67 225.6 3.3 2.1e-66 223.9 3.3 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.11 001299747.1_18529001_1 - 3.3e-21 75.3 7.4 3.3e-21 75.3 7.4 4.4 3 1 1 4 4 4 1 HSA Helicase_C PF00271.29 001299747.1_18529001_1 - 4.1e-20 72.1 2.0 1.2e-19 70.6 0.1 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain bZIP_Maf PF03131.15 001299710.1_18522001_3 - 8.7e-28 96.6 8.1 8.7e-28 96.6 8.1 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor Mo-co_dimer PF03404.14 001299710.1_18522001_3 - 0.0042 17.0 0.1 0.006 16.5 0.1 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Ribosomal_L29e PF01779.15 166438.4_18521001_2 - 1.5e-20 73.0 9.2 3.2e-20 72.0 9.2 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family 3HCDH_N PF02737.16 137130.3_18523001_3 - 7.1e-46 156.2 0.0 1.5e-45 155.1 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.20 137130.3_18523001_3 - 1.3e-14 54.5 0.0 2.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.17 137130.3_18523001_3 - 4.7e-06 25.9 0.0 0.00012 21.3 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.13 137130.3_18523001_3 - 0.00071 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Spc7 PF08317.9 137130.3_18523001_3 - 0.0011 17.7 1.0 0.0011 17.7 1.0 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein ApbA PF02558.14 137130.3_18523001_3 - 0.0038 16.7 0.1 0.0061 16.1 0.1 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA adh_short PF00106.23 137130.3_18523001_3 - 0.011 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.12 137130.3_18523001_3 - 0.012 15.1 0.0 0.025 14.0 0.0 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.4 137130.3_18523001_3 - 0.016 15.3 0.6 0.062 13.4 0.3 2.1 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.21 137130.3_18523001_3 - 0.017 15.0 0.0 0.027 14.3 0.0 1.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.12 137130.3_18523001_3 - 0.024 13.8 0.1 0.072 12.2 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 137130.3_18523001_3 - 0.047 14.1 0.1 0.14 12.6 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.15 137130.3_18523001_3 - 0.048 14.1 0.1 0.11 12.9 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.4 137130.3_18523001_3 - 0.058 12.8 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SKA2 PF16740.3 137130.3_18523001_3 - 0.37 10.5 3.3 0.23 11.1 1.1 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 A_deaminase PF00962.20 137133.2_18524001_1 - 5e-21 75.2 0.0 7.1e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.9 137133.2_18524001_1 - 1e-15 57.7 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal zf-BED PF02892.13 166069.3_18523001_3 - 5.6e-19 67.8 3.8 1.2e-18 66.7 3.8 1.6 1 0 0 1 1 1 1 BED zinc finger BESS PF02944.18 166069.3_18523001_3 - 1.4e-11 43.9 0.6 2.6e-11 43.0 0.6 1.5 1 0 0 1 1 1 1 BESS motif Thymopoietin PF08198.9 166072.3_18522001_2 - 0.13 11.7 0.5 0.35 10.4 0.5 1.6 1 0 0 1 1 1 0 Thymopoietin protein CTD_bind PF04818.11 001299499.1_18529001_3 - 2.2e-06 28.3 0.2 8.3e-06 26.4 0.2 2.1 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Siah-Interact_N PF09032.9 001299499.1_18529001_3 - 0.02 15.0 0.6 0.02 15.0 0.6 3.9 4 0 0 4 4 4 0 Siah interacting protein, N terminal p450 PF00067.20 143818.3_18524001_2 - 1.6e-98 330.3 0.0 1.9e-98 330.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4388 PF14332.4 143818.3_18524001_2 - 0.0028 17.8 0.1 0.0055 16.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4388) p450 PF00067.20 001299503.1_18524001_2 - 2.5e-98 329.7 0.0 2.9e-98 329.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4388 PF14332.4 001299503.1_18524001_2 - 0.0034 17.5 0.1 0.0068 16.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4388) Ank_2 PF12796.5 137161.1_18529001_1 - 6.6e-23 81.0 5.0 5.3e-13 49.2 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.4 137161.1_18529001_1 - 6.1e-20 70.9 3.6 9.9e-09 35.2 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.4 137161.1_18529001_1 - 2.9e-19 67.0 1.8 4.3e-05 23.4 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.4 137161.1_18529001_1 - 1.6e-18 66.7 0.6 4.8e-09 36.4 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.28 137161.1_18529001_1 - 4.1e-16 58.5 3.3 0.00024 21.3 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat DUF3421 PF11901.6 137700.4_18523001_2 - 2.8e-54 181.9 1.3 1.6e-41 140.8 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Methyltransf_FA PF12248.6 137700.4_18523001_2 - 7.1e-31 106.4 0.0 2e-30 105.0 0.0 1.7 2 0 0 2 2 2 1 Farnesoic acid 0-methyl transferase RYDR_ITPR PF01365.19 057645.3_18529001_2 - 1.2e-132 439.4 9.8 2.1e-77 259.1 0.1 3.9 4 0 0 4 4 4 2 RIH domain RyR PF02026.14 057645.3_18529001_2 - 1.4e-122 400.1 6.9 1.7e-30 104.9 0.1 5.1 4 0 0 4 4 4 4 RyR domain SPRY PF00622.26 057645.3_18529001_2 - 5.9e-68 226.4 2.6 2e-22 79.4 0.0 3.6 3 0 0 3 3 3 3 SPRY domain Ins145_P3_rec PF08709.9 057645.3_18529001_2 - 2.8e-64 216.1 0.1 5.2e-64 215.2 0.1 1.4 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RR_TM4-6 PF06459.10 057645.3_18529001_2 - 2.2e-54 185.1 0.0 2.2e-54 185.1 0.0 3.1 2 1 0 2 2 1 1 Ryanodine Receptor TM 4-6 MIR PF02815.17 057645.3_18529001_2 - 5.9e-53 179.3 0.2 2.2e-47 161.2 0.0 2.7 2 0 0 2 2 2 2 MIR domain RIH_assoc PF08454.9 057645.3_18529001_2 - 6.8e-30 102.8 8.4 2e-29 101.3 0.1 4.3 4 0 0 4 4 4 1 RyR and IP3R Homology associated Ion_trans PF00520.29 057645.3_18529001_2 - 1.7e-13 50.2 8.3 4.4e-13 48.9 8.3 1.7 1 0 0 1 1 1 1 Ion transport protein GWT1 PF06423.10 057645.3_18529001_2 - 0.0012 18.9 1.0 0.048 13.7 0.0 2.9 2 0 0 2 2 2 1 GWT1 EF-hand_7 PF13499.4 057645.3_18529001_2 - 0.017 15.4 0.0 0.077 13.3 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.4 057645.3_18529001_2 - 0.039 13.6 0.0 0.16 11.6 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair DUF996 PF06195.11 057645.3_18529001_2 - 0.85 9.8 4.1 1.8 8.7 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) PHD PF00628.27 001273969.1_18529001_3 - 2.5e-21 75.2 19.2 3.3e-11 42.7 8.2 2.6 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.23 001273969.1_18529001_3 - 9.1e-21 73.6 0.0 2.1e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain WSD PF15613.4 001273969.1_18529001_3 - 4e-10 40.0 2.2 5.7e-06 26.6 0.1 4.3 4 0 0 4 4 4 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.15 001273969.1_18529001_3 - 1.7e-07 31.3 3.4 3.7e-07 30.2 3.4 1.6 1 0 0 1 1 1 1 DDT domain MBD PF01429.17 001273969.1_18529001_3 - 2.3e-07 30.3 0.0 5.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain WHIM1 PF15612.4 001273969.1_18529001_3 - 5.4e-05 22.5 0.0 0.00013 21.3 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.4 001273969.1_18529001_3 - 8.2e-05 21.9 12.7 0.0035 16.7 3.2 2.5 2 0 0 2 2 2 2 PHD-finger Zf_RING PF16744.3 001273969.1_18529001_3 - 0.79 9.7 9.6 7.2 6.7 2.5 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger Prok-RING_1 PF14446.4 001273969.1_18529001_3 - 1.1 9.1 12.3 3.7 7.4 1.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.20 001273969.1_18529001_3 - 6.6 6.6 12.0 1.2 8.9 3.0 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MADF_DNA_bdg PF10545.7 138016.3_18522001_2 - 6.1e-21 74.4 1.9 6.1e-21 74.4 1.9 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF334 PF03904.11 138016.3_18522001_2 - 0.012 15.0 1.2 0.012 15.0 1.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF334) SANT_DAMP1_like PF16282.3 138016.3_18522001_2 - 0.021 14.9 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 PBC PF03792.11 138016.3_18522001_2 - 0.053 13.2 1.9 0.13 12.0 0.4 2.0 2 0 0 2 2 2 0 PBC domain Myb_DNA-bind_4 PF13837.4 138016.3_18522001_2 - 0.11 12.8 4.3 0.18 12.1 2.7 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain CortBP2 PF09727.7 001299636.1_18527001_1 - 1.7e-59 200.8 51.9 1.7e-58 197.6 26.1 2.2 2 0 0 2 2 2 2 Cortactin-binding protein-2 FlaC_arch PF05377.9 001299636.1_18527001_1 - 0.2 11.9 5.6 1.2 9.4 0.2 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Borrelia_lipo_2 PF06238.9 001299636.1_18527001_1 - 0.23 11.7 1.8 1 9.6 1.9 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein DUF3421 PF11901.6 001274141.2_18525001_1 - 4.5e-31 107.1 0.5 6e-30 103.5 0.1 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) zf-RING_2 PF13639.4 001274141.2_18525001_1 - 5.5e-12 45.6 6.5 1.7e-11 44.0 6.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.4 001274141.2_18525001_1 - 1.2e-09 37.7 4.3 3.2e-09 36.3 4.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001274141.2_18525001_1 - 5.9e-09 36.0 6.3 1.8e-08 34.4 6.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.4 001274141.2_18525001_1 - 1.6e-08 34.3 2.4 3.9e-08 33.0 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001274141.2_18525001_1 - 5.1e-08 32.5 4.7 1.3e-07 31.2 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001274141.2_18525001_1 - 1.1e-05 25.1 4.9 1.1e-05 25.1 4.9 2.5 3 0 0 3 3 1 1 zinc-RING finger domain zf-RING_11 PF17123.3 001274141.2_18525001_1 - 1.5e-05 24.4 4.1 4e-05 23.1 4.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.4 001274141.2_18525001_1 - 1.9e-05 24.3 6.7 5.5e-05 22.8 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.3 001274141.2_18525001_1 - 3.1e-05 23.4 3.7 7.9e-05 22.1 3.7 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.5 001274141.2_18525001_1 - 0.00061 19.7 2.1 0.0014 18.5 2.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.5 001274141.2_18525001_1 - 0.0082 16.1 5.5 0.02 14.9 5.5 1.6 1 0 0 1 1 1 1 RING-variant domain Prok-RING_1 PF14446.4 001274141.2_18525001_1 - 0.011 15.5 0.4 0.011 15.5 0.4 2.2 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.27 001274141.2_18525001_1 - 0.012 15.4 3.0 0.035 13.9 3.0 1.9 1 0 0 1 1 1 0 PHD-finger Rtf2 PF04641.10 001274141.2_18525001_1 - 0.021 14.1 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Zf_RING PF16744.3 001274141.2_18525001_1 - 0.022 14.7 2.5 0.053 13.5 2.5 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-Nse PF11789.6 001274141.2_18525001_1 - 0.044 13.5 2.0 0.11 12.2 2.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.9 001274141.2_18525001_1 - 0.045 13.9 5.8 0.12 12.6 5.8 1.8 1 0 0 1 1 1 0 RING-like domain PDZ PF00595.22 079973.3_18524001_2 - 2e-15 56.8 0.1 4.7e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 079973.3_18524001_2 - 2.5e-07 30.8 0.1 5e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.4 079973.3_18524001_2 - 0.049 13.5 0.1 0.099 12.5 0.1 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain HSL_N PF06350.10 166381.2_18528001_1 - 6.3e-126 419.4 0.1 1.3e-125 418.3 0.0 1.6 2 0 0 2 2 2 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.11 166381.2_18528001_1 - 3.9e-40 137.8 0.0 5.6e-30 104.6 0.1 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.7 166381.2_18528001_1 - 0.0019 17.0 0.0 0.0038 16.0 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase IMPDH PF00478.23 166381.2_18528001_1 - 0.17 10.7 0.1 0.24 10.2 0.1 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain HSL_N PF06350.10 137619.3_18528001_2 - 6.1e-126 419.4 0.1 1.3e-125 418.3 0.0 1.6 2 0 0 2 2 2 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.11 137619.3_18528001_2 - 3.8e-40 137.9 0.0 5.5e-30 104.7 0.1 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.7 137619.3_18528001_2 - 0.0019 17.0 0.0 0.0038 16.0 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase IMPDH PF00478.23 137619.3_18528001_2 - 0.17 10.8 0.1 0.24 10.2 0.1 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Ribosomal_L7Ae PF01248.24 136420.4_18523001_3 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peptidase_S24 PF00717.21 137657.3_18522001_3 - 1.6e-07 31.0 0.1 3.6e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.7 137657.3_18522001_3 - 0.0024 17.6 0.0 0.37 10.4 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Aldedh PF00171.20 001273843.1_18524001_1 - 3.9e-83 279.4 0.0 4.8e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cyt-b5 PF00173.26 137575.2_18524001_3 - 1.2e-19 70.1 0.0 2.2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.22 137575.2_18524001_3 - 4.6e-13 49.2 0.0 1.4e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.19 137575.2_18524001_3 - 8.9e-12 45.5 0.0 1.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.10 137575.2_18524001_3 - 8.5e-09 35.6 0.0 3.4e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain MOZ_SAS PF01853.16 001299894.1_18529001_3 - 3e-78 261.5 1.4 8.3e-78 260.0 1.4 1.8 1 0 0 1 1 1 1 MOZ/SAS family Linker_histone PF00538.17 001299894.1_18529001_3 - 4e-09 36.6 1.5 0.00045 20.4 0.2 2.8 2 0 0 2 2 2 2 linker histone H1 and H5 family PHD PF00628.27 001299894.1_18529001_3 - 3.2e-05 23.6 28.1 4.1e-05 23.3 10.3 3.1 2 1 1 3 3 3 2 PHD-finger Acetyltransf_7 PF13508.5 001299894.1_18529001_3 - 0.0074 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Spectrin PF00435.19 001299894.1_18529001_3 - 0.064 13.6 4.9 4 7.8 0.1 3.0 2 0 0 2 2 2 0 Spectrin repeat mono-CXXC PF15626.4 137820.2_18522001_1 - 0.058 13.6 4.8 0.15 12.3 0.6 2.3 2 0 0 2 2 2 0 single CXXC unit Stathmin PF00836.17 137820.2_18522001_2 - 4.8e-08 32.9 6.5 4.8e-08 32.9 6.5 1.4 1 1 0 1 1 1 1 Stathmin family DUF106 PF01956.14 137820.2_18522001_2 - 0.99 9.0 3.0 0.44 10.1 0.5 1.6 2 0 0 2 2 2 0 Integral membrane protein DUF106 PA26 PF04636.11 001299849.1_18525001_1 - 2.8e-194 646.0 0.0 3.6e-194 645.6 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) PRCC PF10253.7 137981.2_18522001_2 - 0.45 11.1 6.5 0.61 10.7 6.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF1049 PF06305.9 137981.2_18522001_2 - 0.68 9.7 4.0 1.2 8.8 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Tetraspannin PF00335.18 057900.4_18523001_3 - 5.6e-30 104.6 12.6 7.5e-30 104.2 12.6 1.1 1 0 0 1 1 1 1 Tetraspanin family PID PF00640.21 165676.2_18526001_2 - 1.1e-22 80.4 0.1 2.2e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.11 165676.2_18526001_2 - 0.00084 19.4 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.4 165676.2_18526001_2 - 0.046 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Plasmid_RAQPRD PF09686.8 165676.2_18526001_2 - 0.055 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) BLOC1S3 PF15753.3 165676.2_18526001_2 - 0.065 13.2 0.6 0.13 12.2 0.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 BTB PF00651.29 170620.4_18527001_1 - 2.9e-25 88.5 0.4 5.6e-25 87.6 0.4 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.4 170620.4_18527001_1 - 0.00039 20.9 14.2 0.049 14.3 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.24 170620.4_18527001_1 - 0.0046 17.2 15.9 0.1 13.0 3.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.5 170620.4_18527001_1 - 0.078 13.2 3.6 1.9 8.7 1.3 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.5 170620.4_18527001_1 - 0.14 12.4 13.1 0.098 12.9 2.4 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1079 PF06435.9 170620.4_18527001_1 - 0.17 12.0 5.2 0.54 10.4 0.8 2.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) zf-C2H2_jaz PF12171.6 170620.4_18527001_1 - 1.9 8.7 9.0 11 6.3 1.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BTB PF00651.29 170618.5_18527001_3 - 2.7e-25 88.6 0.4 5e-25 87.8 0.4 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_5 PF13909.4 170618.5_18527001_3 - 7e-05 22.4 0.6 0.00019 21.0 0.6 1.8 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.24 170618.5_18527001_3 - 0.0011 19.1 8.0 0.0036 17.5 0.4 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 170618.5_18527001_3 - 0.014 16.1 0.4 0.014 16.1 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.10 170618.5_18527001_3 - 0.13 12.5 4.7 0.83 9.8 4.5 2.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF1079 PF06435.9 170618.5_18527001_3 - 0.14 12.3 5.2 0.48 10.5 0.8 2.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) polyprenyl_synt PF00348.15 058032.5_18523001_3 - 3.1e-90 301.6 0.2 4.2e-90 301.1 0.2 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3716 PF12511.6 137111.3_18525001_2 - 0.31 11.0 2.7 1 9.3 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Ribosomal_60s PF00428.17 137111.3_18525001_2 - 0.42 11.1 4.8 0.87 10.0 4.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein NHL PF01436.19 001299207.1_18525001_1 - 2.9e-36 121.5 0.3 3.6e-06 26.6 0.1 7.2 7 0 0 7 7 7 5 NHL repeat Thioredoxin_8 PF13905.4 001299207.1_18525001_1 - 1e-09 38.4 0.0 3.1e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like SGL PF08450.10 001299207.1_18525001_1 - 6.7e-05 22.5 0.0 0.00063 19.3 0.0 2.4 3 0 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.18 001299207.1_18525001_1 - 0.0066 16.5 0.1 8.5 6.5 0.0 3.5 4 0 0 4 4 4 2 Arylesterase SdiA-regulated PF06977.9 001299207.1_18525001_1 - 0.031 13.4 0.0 7.6 5.5 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated Pkinase PF00069.23 001300706.2_18525001_1 - 1.8e-65 220.8 0.0 2.3e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001300706.2_18525001_1 - 1.5e-33 116.1 0.0 2.6e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001300706.2_18525001_1 - 0.00079 19.3 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C2H2_4 PF13894.4 136686.4_18522001_2 - 2.2e-07 31.0 14.2 0.0097 16.5 1.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.24 136686.4_18522001_2 - 6.6e-05 23.0 13.6 0.012 15.9 0.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 136686.4_18522001_2 - 0.0017 18.5 9.1 0.37 11.0 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.4 136686.4_18522001_2 - 0.019 14.8 1.4 12 5.8 0.3 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.5 136686.4_18522001_2 - 0.043 14.1 10.7 0.35 11.2 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 136686.4_18522001_2 - 0.14 12.0 4.4 0.86 9.5 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.5 136686.4_18522001_2 - 0.18 12.0 10.1 0.67 10.2 0.1 3.1 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) HNH PF01844.21 136686.4_18522001_2 - 4.2 7.5 7.3 14 5.8 0.2 2.9 3 0 0 3 3 3 0 HNH endonuclease OTT_1508_deam PF14441.4 136686.4_18522001_2 - 8.4 6.3 7.2 20 5.0 2.3 2.9 2 1 0 2 2 2 0 OTT_1508-like deaminase Mon1 PF03164.12 137153.4_18525001_3 - 0.00049 19.1 0.0 0.0079 15.2 0.0 2.4 2 1 0 2 2 2 1 Trafficking protein Mon1 DUF2779 PF11074.6 137153.4_18525001_3 - 0.0039 17.5 0.2 0.0084 16.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) Glyco_transf_92 PF01697.25 001273929.1_18525001_1 - 5.5e-45 153.9 1.8 8.1e-45 153.4 1.8 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.4 001273929.1_18525001_1 - 0.0055 17.1 0.8 0.013 15.8 0.8 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 MWFE PF15879.3 001299351.1_18524001_1 - 0.49 10.5 0.0 0.49 10.5 0.0 2.4 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit SR-25 PF10500.7 001299351.1_18524001_1 - 3.2 7.2 20.1 0.45 10.0 16.0 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein WASH_WAHD PF11945.6 001299405.1_18524001_1 - 1.6e-79 267.4 0.0 2.1e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex HD_4 PF13328.4 001299405.1_18524001_1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 HD domain Dynein_attach_N PF15867.3 136831.2_18521001_3 - 3e-25 87.8 0.1 4.2e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RFXA_RFXANK_bdg PF15289.4 137059.3_18522001_3 - 0.0046 17.2 1.8 0.0046 17.2 1.8 2.0 1 1 1 2 2 2 1 Regulatory factor X-associated C-terminal binding domain Homeobox PF00046.27 001299706.1_18524001_1 - 1.2e-21 76.2 5.3 1.2e-21 76.2 5.3 1.9 3 0 0 3 3 3 1 Homeobox domain Homeobox_KN PF05920.9 001299706.1_18524001_1 - 0.013 15.3 0.5 0.028 14.2 0.5 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF3602 PF12223.6 001299706.1_18524001_3 - 0.15 12.5 1.2 0.32 11.5 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) I-set PF07679.14 001299716.1_18526001_2 - 8.1e-18 64.1 0.0 4.7e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.4 001299716.1_18526001_2 - 8e-17 61.5 0.0 1.1e-08 35.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001299716.1_18526001_2 - 5.8e-16 58.5 2.0 1.5e-08 34.6 0.1 2.8 3 0 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.23 001299716.1_18526001_2 - 6.4e-12 45.4 2.0 4e-05 23.6 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.4 001299716.1_18526001_2 - 1.6e-09 37.9 0.0 0.00018 21.6 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain PBP_GOBP PF01395.20 137866.2_18522001_1 - 1.9e-07 31.1 0.3 1.9e-07 31.1 0.3 2.1 1 1 1 2 2 2 1 PBP/GOBP family OCIA PF07051.9 137889.3_18523001_3 - 3.6e-39 132.5 0.2 5.2e-39 132.0 0.2 1.2 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) DUF5118 PF17162.2 001169744.2_18527001_2 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) DDE_3 PF13358.4 001299601.1_18529001_3 - 2.3e-20 72.7 0.0 5.1e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease FAD_binding_4 PF01565.21 001299601.1_18529001_3 - 0.18 11.4 0.5 0.5 10.0 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Kinesin_assoc PF16183.3 001299601.1_18529001_3 - 3.5 7.6 7.0 11 6.0 6.8 2.0 1 1 0 1 1 1 0 Kinesin-associated UCR_6-4kD PF08997.8 137389.4_18521001_3 - 5.5e-22 77.3 0.1 7.1e-22 77.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.7 137389.4_18521001_3 - 0.0021 18.0 1.8 0.01 15.7 1.8 1.9 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF2346 PF09803.7 137391.4_18522001_1 - 5.2e-29 100.5 2.9 7.1e-29 100.0 2.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) DUF2346 PF09803.7 001299612.1_18522001_1 - 1.6e-28 98.8 2.9 2.4e-28 98.3 2.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) MORN PF02493.18 137430.2_18522001_1 - 9.9e-23 78.5 30.5 1.3e-05 24.7 0.7 6.5 6 0 0 6 6 6 6 MORN repeat Trypsin PF00089.24 136522.2_18524001_1 - 8.6e-42 143.3 0.0 1.4e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.18 136522.2_18524001_1 - 1.1e-06 28.8 0.1 2.4e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 CUB domain Adeno_terminal PF02459.13 136522.2_18524001_1 - 1.3 7.2 3.8 2 6.5 3.8 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PSI_integrin PF17205.1 136522.2_18524001_3 - 0.38 10.5 3.9 6.4 6.6 0.5 2.6 2 0 0 2 2 2 0 Integrin plexin domain DIM PF08194.10 137476.4_18522001_1 - 2e-08 34.1 1.8 2e-08 34.1 1.8 2.3 2 0 0 2 2 2 1 DIM protein MFS_1 PF07690.14 166308.2_18524001_2 - 2.4e-57 194.3 26.2 9.5e-55 185.8 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 166308.2_18524001_2 - 1.6e-10 40.3 12.3 1.6e-10 40.3 12.3 2.4 1 1 0 2 2 2 2 Sugar (and other) transporter zf-C3HC4 PF00097.23 001299669.1_18527001_2 - 2.6e-06 27.1 10.7 2.6e-06 27.1 10.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001299669.1_18527001_2 - 8.7e-06 25.5 9.2 8.7e-06 25.5 9.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 001299669.1_18527001_2 - 0.00056 19.6 11.7 0.00056 19.6 11.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001299669.1_18527001_2 - 0.0017 18.4 11.6 0.0017 18.4 11.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.22 001299669.1_18527001_2 - 0.013 15.5 8.8 0.013 15.5 8.8 2.3 2 0 0 2 2 2 0 B-box zinc finger zf-RING_5 PF14634.4 001299669.1_18527001_2 - 1.7 8.5 25.0 0.013 15.3 10.1 2.5 2 0 0 2 2 2 0 zinc-RING finger domain WH1 PF00568.21 001299673.1_18529001_1 - 8.2e-33 112.5 0.4 1.5e-32 111.7 0.4 1.4 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.9 001299673.1_18529001_1 - 1.4e-15 56.4 2.3 3.1e-15 55.3 2.3 1.6 1 0 0 1 1 1 1 VASP tetramerisation domain Ran_BP1 PF00638.16 001299673.1_18529001_1 - 0.00028 21.0 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.21 001014536.2_18527001_2 - 5.9e-33 113.0 0.4 1.1e-32 112.1 0.4 1.4 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.9 001014536.2_18527001_2 - 1.3e-15 56.5 2.3 2.3e-15 55.7 2.3 1.4 1 0 0 1 1 1 1 VASP tetramerisation domain Ran_BP1 PF00638.16 001014536.2_18527001_2 - 0.00021 21.4 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DIM PF08194.10 144038.3_18521001_2 - 0.006 16.6 0.6 0.01 15.9 0.6 1.3 1 0 0 1 1 1 1 DIM protein RhoGEF PF00621.18 166218.2_18524001_3 - 7.2e-24 84.9 1.9 1.3e-23 84.1 1.9 1.4 1 0 0 1 1 1 1 RhoGEF domain SopD PF11047.6 166218.2_18524001_3 - 0.0059 15.7 0.0 0.025 13.7 0.0 1.8 2 0 0 2 2 2 1 Salmonella outer protein D Glyco_hydro_25 PF01183.18 166218.2_18524001_3 - 0.078 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 25 MADF_DNA_bdg PF10545.7 206028.2_18524001_2 - 4.6e-21 74.8 4.4 4.6e-21 74.8 4.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.4 206028.2_18524001_2 - 0.0012 19.1 2.1 0.0029 17.8 2.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.4 206028.2_18524001_2 - 0.016 15.1 0.3 0.13 12.2 0.4 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_AsnC-type PF13404.4 206028.2_18524001_2 - 0.08 12.6 2.5 0.12 12.1 0.0 2.6 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Fis1_TPR_C PF14853.4 001299211.1_18522001_3 - 5.5e-18 64.7 1.1 8.3e-18 64.1 1.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Mlp PF03304.11 001299211.1_18522001_3 - 0.027 14.6 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Mlp lipoprotein family GST_N_3 PF13417.4 137486.5_18522001_3 - 4.8e-19 68.4 0.0 8.4e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 137486.5_18522001_3 - 3e-14 53.0 0.0 4.7e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 137486.5_18522001_3 - 6e-10 39.2 0.0 1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 137486.5_18522001_3 - 1.3e-08 34.8 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 137486.5_18522001_3 - 1.1e-07 31.9 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 137486.5_18522001_3 - 4.9e-06 26.3 0.0 9.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 137486.5_18522001_3 - 0.041 14.0 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin zf-MYND PF01753.16 138001.4_18524001_3 - 1.5e-11 44.1 11.8 8.9e-06 25.6 3.9 2.8 2 0 0 2 2 2 2 MYND finger zf-Mss51 PF13824.4 138001.4_18524001_3 - 0.0004 20.3 0.8 0.0004 20.3 0.8 2.5 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 ASL_C PF08328.9 138001.4_18524001_3 - 0.14 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Ig_3 PF13927.4 206047.1_18529001_1 - 6.8e-110 359.7 9.7 2.2e-13 50.5 0.0 11.1 11 0 0 11 11 11 10 Immunoglobulin domain I-set PF07679.14 206047.1_18529001_1 - 3.5e-107 350.6 7.1 1.5e-14 53.6 0.0 11.7 11 0 0 11 11 11 10 Immunoglobulin I-set domain fn3 PF00041.19 206047.1_18529001_1 - 1.5e-74 246.2 24.5 3.5e-16 59.2 0.8 6.6 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.4 206047.1_18529001_1 - 2.1e-70 232.9 0.3 6.3e-08 32.7 0.0 10.7 10 0 0 10 10 10 10 Immunoglobulin domain Dscam_C PF12355.6 206047.1_18529001_1 - 1.4e-62 209.7 22.0 4.7e-57 191.9 14.6 2.7 2 0 0 2 2 2 2 Down syndrome cell adhesion molecule C terminal ig PF00047.23 206047.1_18529001_1 - 1e-60 201.8 0.3 3.2e-08 33.5 0.0 10.7 10 0 0 10 10 10 9 Immunoglobulin domain V-set PF07686.15 206047.1_18529001_1 - 2e-26 92.1 6.5 0.026 14.6 0.0 12.4 10 4 1 11 11 11 7 Immunoglobulin V-set domain C2-set_2 PF08205.10 206047.1_18529001_1 - 6.7e-19 67.6 0.9 0.0038 17.1 0.0 9.5 9 0 0 9 9 9 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 206047.1_18529001_1 - 2.3e-15 56.6 0.9 0.037 14.3 0.0 8.8 9 1 0 9 9 8 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 206047.1_18529001_1 - 1.1e-10 41.8 21.0 0.0067 16.8 0.3 6.5 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.3 206047.1_18529001_1 - 2.8e-07 30.7 4.6 0.027 14.7 0.0 7.9 8 1 0 8 8 8 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.3 206047.1_18529001_1 - 5.4e-06 26.2 0.6 8.2 6.4 0.0 6.6 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 206047.1_18529001_1 - 0.0015 18.5 1.0 4 7.6 0.0 5.3 7 0 0 7 7 6 1 Natural killer cell receptor 2B4 LAX PF15681.3 206047.1_18529001_1 - 0.015 13.9 0.0 0.031 12.8 0.0 1.5 1 0 0 1 1 1 0 Lymphocyte activation family X C2-set PF05790.13 206047.1_18529001_1 - 0.018 15.1 0.1 41 4.3 0.0 5.0 6 0 0 6 6 5 0 Immunoglobulin C2-set domain ASH PF15780.3 206047.1_18529001_1 - 0.16 12.0 3.6 2.3 8.3 0.3 3.2 3 0 0 3 3 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Ig_3 PF13927.4 078925.5_18529001_1 - 3.2e-108 354.4 5.9 2.2e-13 50.5 0.0 11.1 11 0 0 11 11 11 9 Immunoglobulin domain I-set PF07679.14 078925.5_18529001_1 - 8.7e-108 352.5 3.7 1.5e-14 53.6 0.0 11.3 11 0 0 11 11 11 9 Immunoglobulin I-set domain fn3 PF00041.19 078925.5_18529001_1 - 1.5e-74 246.2 24.5 3.5e-16 59.2 0.8 6.5 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.4 078925.5_18529001_1 - 1.1e-66 221.0 0.0 6.3e-08 32.7 0.0 10.7 10 0 0 10 10 10 9 Immunoglobulin domain Dscam_C PF12355.6 078925.5_18529001_1 - 1.4e-62 209.7 22.0 4.7e-57 191.9 14.6 2.7 2 0 0 2 2 2 2 Down syndrome cell adhesion molecule C terminal ig PF00047.23 078925.5_18529001_1 - 8.3e-57 189.2 0.0 1.4e-06 28.2 0.0 10.6 10 0 0 10 10 10 8 Immunoglobulin domain V-set PF07686.15 078925.5_18529001_1 - 1.8e-27 95.5 4.7 0.028 14.4 0.0 11.6 9 4 1 10 10 10 7 Immunoglobulin V-set domain C2-set_2 PF08205.10 078925.5_18529001_1 - 8.6e-19 67.3 0.3 0.0038 17.1 0.0 9.3 9 0 0 9 9 9 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 078925.5_18529001_1 - 2.4e-15 56.6 0.7 0.037 14.3 0.0 9.1 10 1 0 10 10 9 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 078925.5_18529001_1 - 1.4e-10 41.5 21.0 0.0067 16.8 0.3 6.2 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.3 078925.5_18529001_1 - 3.1e-08 33.7 3.1 0.027 14.7 0.0 8.3 9 1 0 9 9 8 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.3 078925.5_18529001_1 - 7.9e-07 28.9 0.3 8.2 6.4 0.0 6.9 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 078925.5_18529001_1 - 0.0049 16.9 1.2 11 6.1 0.0 5.2 7 0 0 7 7 6 0 Natural killer cell receptor 2B4 C2-set PF05790.13 078925.5_18529001_1 - 0.013 15.5 0.0 41 4.3 0.0 5.1 6 0 0 6 6 6 0 Immunoglobulin C2-set domain LAX PF15681.3 078925.5_18529001_1 - 0.015 13.9 0.0 0.031 12.8 0.0 1.5 1 0 0 1 1 1 0 Lymphocyte activation family X ASH PF15780.3 078925.5_18529001_1 - 0.19 11.8 3.6 2.3 8.3 0.3 3.1 3 0 0 3 3 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Ig_3 PF13927.4 165513.1_18529001_1 - 1.4e-110 361.9 5.2 2.2e-13 50.5 0.0 11.1 11 0 0 11 11 11 10 Immunoglobulin domain I-set PF07679.14 165513.1_18529001_1 - 9.9e-110 358.7 2.8 1.5e-14 53.7 0.0 11.7 11 0 0 11 11 11 9 Immunoglobulin I-set domain fn3 PF00041.19 165513.1_18529001_1 - 1.5e-74 246.3 24.5 3.5e-16 59.2 0.8 6.6 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.4 165513.1_18529001_1 - 8.8e-69 227.7 0.0 6.3e-08 32.7 0.0 10.7 10 0 0 10 10 10 10 Immunoglobulin domain Dscam_C PF12355.6 165513.1_18529001_1 - 1.4e-62 209.8 22.0 4.7e-57 191.9 14.6 2.7 2 0 0 2 2 2 2 Down syndrome cell adhesion molecule C terminal ig PF00047.23 165513.1_18529001_1 - 1.3e-56 188.6 0.0 1.4e-06 28.2 0.0 10.6 10 0 0 10 10 10 8 Immunoglobulin domain V-set PF07686.15 165513.1_18529001_1 - 1.2e-28 99.3 4.8 0.028 14.4 0.0 12.4 10 4 1 11 11 11 7 Immunoglobulin V-set domain C2-set_2 PF08205.10 165513.1_18529001_1 - 7.9e-19 67.4 0.3 0.0038 17.1 0.0 9.3 9 0 0 9 9 9 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 165513.1_18529001_1 - 2.1e-15 56.8 0.7 0.037 14.3 0.0 9.2 10 1 0 10 10 9 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 165513.1_18529001_1 - 1.3e-10 41.5 21.0 0.0067 16.8 0.3 6.3 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.3 165513.1_18529001_1 - 3.2e-08 33.7 3.2 0.027 14.7 0.0 8.4 9 1 0 9 9 8 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.3 165513.1_18529001_1 - 7.7e-07 28.9 0.3 8.2 6.4 0.0 6.9 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 165513.1_18529001_1 - 0.0047 17.0 1.2 11 6.1 0.0 5.3 7 0 0 7 7 6 0 Natural killer cell receptor 2B4 C2-set PF05790.13 165513.1_18529001_1 - 0.013 15.6 0.0 41 4.3 0.0 5.1 6 0 0 6 6 6 0 Immunoglobulin C2-set domain LAX PF15681.3 165513.1_18529001_1 - 0.015 13.9 0.0 0.031 12.8 0.0 1.5 1 0 0 1 1 1 0 Lymphocyte activation family X ASH PF15780.3 165513.1_18529001_1 - 0.14 12.3 3.2 2.3 8.3 0.3 3.1 3 0 0 3 3 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Ig_3 PF13927.4 001043025.1_18529001_1 - 2.3e-110 361.2 5.8 2.2e-13 50.5 0.0 11.1 11 0 0 11 11 11 10 Immunoglobulin domain I-set PF07679.14 001043025.1_18529001_1 - 9.6e-109 355.6 7.0 1.5e-14 53.6 0.0 11.6 11 0 0 11 11 11 9 Immunoglobulin I-set domain fn3 PF00041.19 001043025.1_18529001_1 - 1.3e-74 246.5 24.5 3.5e-16 59.2 0.8 6.7 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.4 001043025.1_18529001_1 - 3.1e-65 216.3 0.1 6.4e-08 32.7 0.0 10.7 10 0 0 10 10 10 9 Immunoglobulin domain ig PF00047.23 001043025.1_18529001_1 - 4.2e-65 215.8 0.0 1.4e-06 28.2 0.0 10.6 10 0 0 10 10 10 10 Immunoglobulin domain Dscam_C PF12355.6 001043025.1_18529001_1 - 1.2e-62 209.9 22.0 4.7e-57 191.9 14.6 2.9 2 0 0 2 2 2 2 Down syndrome cell adhesion molecule C terminal V-set PF07686.15 001043025.1_18529001_1 - 9.4e-26 90.0 7.3 0.031 14.3 0.0 12.1 10 4 1 11 11 11 7 Immunoglobulin V-set domain C2-set_2 PF08205.10 001043025.1_18529001_1 - 1.1e-18 67.0 0.1 0.0038 17.1 0.0 8.7 8 0 0 8 8 8 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001043025.1_18529001_1 - 2.6e-15 56.5 0.6 0.037 14.3 0.0 9.0 10 1 0 10 10 8 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.13 001043025.1_18529001_1 - 2e-12 47.2 0.1 1.1 9.7 0.0 7.7 7 0 0 7 7 7 3 Immunoglobulin C1-set domain Pur_ac_phosph_N PF16656.3 001043025.1_18529001_1 - 1.6e-10 41.3 21.2 0.0068 16.8 0.3 6.2 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.3 001043025.1_18529001_1 - 1.7e-07 31.3 3.2 0.027 14.7 0.0 7.6 8 1 0 8 8 7 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.3 001043025.1_18529001_1 - 8.7e-07 28.8 0.7 8.3 6.4 0.0 7.1 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 001043025.1_18529001_1 - 0.0021 18.1 0.6 7.2 6.7 0.0 5.3 7 0 0 7 7 6 1 Natural killer cell receptor 2B4 V-set_CD47 PF08204.9 001043025.1_18529001_1 - 0.0031 17.3 0.2 0.17 11.8 0.0 3.9 5 0 0 5 5 5 1 CD47 immunoglobulin-like domain C2-set PF05790.13 001043025.1_18529001_1 - 0.02 15.0 0.0 42 4.3 0.0 4.9 5 0 0 5 5 5 0 Immunoglobulin C2-set domain ASH PF15780.3 001043025.1_18529001_1 - 0.063 13.4 2.0 2.3 8.3 0.3 3.1 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin I-set PF07679.14 001043027.1_18529001_1 - 9.6e-113 368.4 7.1 1.5e-14 53.6 0.0 11.3 11 0 0 11 11 11 9 Immunoglobulin I-set domain Ig_3 PF13927.4 001043027.1_18529001_1 - 2e-112 367.8 6.3 2.2e-13 50.5 0.0 11.1 11 0 0 11 11 11 9 Immunoglobulin domain fn3 PF00041.19 001043027.1_18529001_1 - 1.1e-74 246.6 24.5 3.5e-16 59.2 0.8 6.8 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.4 001043027.1_18529001_1 - 7.9e-73 240.7 0.1 6.4e-08 32.7 0.0 10.6 10 0 0 10 10 10 9 Immunoglobulin domain ig PF00047.23 001043027.1_18529001_1 - 4.1e-66 219.0 0.0 4.9e-07 29.7 0.0 10.6 10 0 0 10 10 10 9 Immunoglobulin domain Dscam_C PF12355.6 001043027.1_18529001_1 - 1.2e-62 209.9 22.0 4.7e-57 191.9 14.6 2.9 2 0 0 2 2 2 2 Down syndrome cell adhesion molecule C terminal V-set PF07686.15 001043027.1_18529001_1 - 7.4e-27 93.5 5.9 0.028 14.4 0.0 12.0 9 5 1 10 10 10 7 Immunoglobulin V-set domain C2-set_2 PF08205.10 001043027.1_18529001_1 - 5.7e-21 74.3 0.3 0.0038 17.1 0.0 9.0 9 0 0 9 9 9 5 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001043027.1_18529001_1 - 6.4e-18 64.8 0.7 0.037 14.3 0.0 9.7 10 1 0 10 10 9 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001043027.1_18529001_1 - 3.3e-10 40.3 22.6 0.0068 16.8 0.3 6.5 6 1 0 6 6 5 4 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.3 001043027.1_18529001_1 - 3.2e-07 30.5 4.5 0.027 14.7 0.0 7.9 9 1 0 9 9 8 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.3 001043027.1_18529001_1 - 3.8e-07 29.9 0.2 8.3 6.4 0.0 6.8 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 001043027.1_18529001_1 - 0.0047 17.0 1.2 11 6.1 0.0 5.2 7 0 0 7 7 6 0 Natural killer cell receptor 2B4 C2-set PF05790.13 001043027.1_18529001_1 - 0.025 14.6 0.0 42 4.3 0.0 4.7 5 0 0 5 5 5 0 Immunoglobulin C2-set domain ASH PF15780.3 001043027.1_18529001_1 - 0.063 13.3 2.0 2.3 8.3 0.3 3.1 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Ig_3 PF13927.4 001043018.1_18529001_1 - 3.7e-115 376.6 4.5 2.2e-13 50.5 0.0 11.1 11 0 0 11 11 11 10 Immunoglobulin domain I-set PF07679.14 001043018.1_18529001_1 - 7.1e-110 359.2 6.1 1.5e-14 53.7 0.0 11.7 11 0 0 11 11 11 9 Immunoglobulin I-set domain fn3 PF00041.19 001043018.1_18529001_1 - 1.5e-74 246.2 24.5 3.5e-16 59.2 0.8 6.5 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.4 001043018.1_18529001_1 - 8.3e-71 234.2 0.0 6.3e-08 32.7 0.0 10.7 10 0 0 10 10 10 10 Immunoglobulin domain ig PF00047.23 001043018.1_18529001_1 - 1.8e-64 213.7 0.0 4.6e-07 29.8 0.0 10.7 10 0 0 10 10 10 9 Immunoglobulin domain Dscam_C PF12355.6 001043018.1_18529001_1 - 1.4e-62 209.7 22.0 4.7e-57 191.9 14.6 2.7 2 0 0 2 2 2 2 Down syndrome cell adhesion molecule C terminal V-set PF07686.15 001043018.1_18529001_1 - 1.2e-27 96.1 6.5 0.026 14.5 0.0 12.3 10 4 1 11 11 11 7 Immunoglobulin V-set domain C2-set_2 PF08205.10 001043018.1_18529001_1 - 7.2e-18 64.3 0.2 0.0038 17.1 0.0 8.5 8 0 0 8 8 8 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001043018.1_18529001_1 - 1.3e-15 57.5 1.0 0.037 14.3 0.0 9.5 10 1 0 10 10 9 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001043018.1_18529001_1 - 1.1e-10 41.8 21.0 0.0067 16.8 0.3 6.4 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain C1-set PF07654.13 001043018.1_18529001_1 - 5.8e-09 36.2 0.1 3.5 8.0 0.0 7.3 7 0 0 7 7 7 2 Immunoglobulin C1-set domain Izumo-Ig PF16706.3 001043018.1_18529001_1 - 8.5e-08 32.0 0.3 6.2 6.8 0.0 6.8 7 0 0 7 7 7 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.3 001043018.1_18529001_1 - 1.8e-07 31.3 4.2 0.027 14.7 0.0 8.1 9 1 0 9 9 8 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.6 001043018.1_18529001_1 - 0.0037 17.3 1.6 9.3 6.4 0.0 5.6 8 0 0 8 8 6 1 Natural killer cell receptor 2B4 LAX PF15681.3 001043018.1_18529001_1 - 0.015 13.9 0.0 0.031 12.8 0.0 1.5 1 0 0 1 1 1 0 Lymphocyte activation family X C2-set PF05790.13 001043018.1_18529001_1 - 0.022 14.8 0.0 41 4.3 0.0 4.8 5 0 0 5 5 5 0 Immunoglobulin C2-set domain ASH PF15780.3 001043018.1_18529001_1 - 0.14 12.3 3.2 2.3 8.3 0.3 3.1 3 0 0 3 3 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin I-set PF07679.14 001043064.1_18529001_1 - 1e-112 368.3 3.3 1.5e-14 53.7 0.0 11.7 11 0 0 11 11 11 9 Immunoglobulin I-set domain Ig_3 PF13927.4 001043064.1_18529001_1 - 1.5e-112 368.2 1.6 2.2e-13 50.5 0.0 11.1 11 0 0 11 11 11 10 Immunoglobulin domain fn3 PF00041.19 001043064.1_18529001_1 - 1.5e-74 246.2 24.5 3.5e-16 59.2 0.8 6.5 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.4 001043064.1_18529001_1 - 1.9e-72 239.5 0.0 6.3e-08 32.7 0.0 10.7 10 0 0 10 10 10 9 Immunoglobulin domain ig PF00047.23 001043064.1_18529001_1 - 4.4e-63 209.3 0.0 1.4e-06 28.2 0.0 10.6 10 0 0 10 10 10 9 Immunoglobulin domain Dscam_C PF12355.6 001043064.1_18529001_1 - 1.4e-62 209.7 22.0 4.7e-57 191.9 14.6 2.7 2 0 0 2 2 2 2 Down syndrome cell adhesion molecule C terminal V-set PF07686.15 001043064.1_18529001_1 - 2.6e-27 95.0 5.2 0.025 14.6 0.0 12.0 10 4 1 11 11 11 7 Immunoglobulin V-set domain C2-set_2 PF08205.10 001043064.1_18529001_1 - 3.6e-18 65.3 0.1 0.0038 17.1 0.0 8.8 9 0 0 9 9 9 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001043064.1_18529001_1 - 6.7e-16 58.4 0.5 0.037 14.3 0.0 9.4 10 1 0 10 10 9 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001043064.1_18529001_1 - 1.4e-10 41.5 21.0 0.0067 16.8 0.3 6.2 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.3 001043064.1_18529001_1 - 1e-07 31.7 0.4 8.2 6.4 0.0 6.9 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.3 001043064.1_18529001_1 - 1e-07 32.0 3.5 0.027 14.7 0.0 8.1 9 1 0 9 9 8 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.6 001043064.1_18529001_1 - 0.0026 17.8 0.6 9.4 6.4 0.0 5.2 7 0 0 7 7 6 1 Natural killer cell receptor 2B4 LAX PF15681.3 001043064.1_18529001_1 - 0.015 13.9 0.0 0.031 12.8 0.0 1.5 1 0 0 1 1 1 0 Lymphocyte activation family X C2-set PF05790.13 001043064.1_18529001_1 - 0.023 14.7 0.0 41 4.3 0.0 4.8 5 0 0 5 5 5 0 Immunoglobulin C2-set domain V-set_CD47 PF08204.9 001043064.1_18529001_1 - 0.041 13.7 0.3 2.3 8.1 0.0 4.0 5 0 0 5 5 5 0 CD47 immunoglobulin-like domain ASH PF15780.3 001043064.1_18529001_1 - 0.1 12.7 2.8 2.3 8.3 0.3 3.2 3 0 0 3 3 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Ig_3 PF13927.4 001043051.1_18529001_1 - 3.7e-113 370.2 6.8 2.2e-13 50.5 0.0 11.2 11 0 0 11 11 11 9 Immunoglobulin domain I-set PF07679.14 001043051.1_18529001_1 - 5.9e-109 356.3 6.4 1.5e-14 53.6 0.0 11.3 11 0 0 11 11 11 9 Immunoglobulin I-set domain fn3 PF00041.19 001043051.1_18529001_1 - 1.5e-74 246.2 24.5 3.5e-16 59.2 0.8 6.5 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.4 001043051.1_18529001_1 - 4.5e-70 231.9 0.1 6.3e-08 32.7 0.0 10.6 10 0 0 10 10 10 9 Immunoglobulin domain ig PF00047.23 001043051.1_18529001_1 - 2.3e-65 216.6 0.0 1.4e-06 28.2 0.0 10.6 10 0 0 10 10 10 9 Immunoglobulin domain Dscam_C PF12355.6 001043051.1_18529001_1 - 1.4e-62 209.7 22.0 4.7e-57 191.9 14.6 2.7 2 0 0 2 2 2 2 Down syndrome cell adhesion molecule C terminal V-set PF07686.15 001043051.1_18529001_1 - 6.6e-27 93.7 9.3 0.025 14.6 0.1 12.2 9 5 1 10 10 10 8 Immunoglobulin V-set domain C2-set_2 PF08205.10 001043051.1_18529001_1 - 5.7e-18 64.6 0.1 0.0038 17.1 0.0 8.5 8 0 0 8 8 8 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001043051.1_18529001_1 - 1.1e-16 60.9 0.7 0.037 14.3 0.0 9.6 10 1 0 10 10 9 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001043051.1_18529001_1 - 1.4e-10 41.5 21.0 0.0067 16.8 0.3 6.3 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain C1-set PF07654.13 001043051.1_18529001_1 - 5.6e-10 39.4 0.1 9 6.7 0.0 7.8 7 0 0 7 7 7 1 Immunoglobulin C1-set domain Ig_4 PF16680.3 001043051.1_18529001_1 - 6.2e-08 32.8 4.2 0.027 14.7 0.0 8.6 9 1 0 9 9 9 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.3 001043051.1_18529001_1 - 6.5e-08 32.4 0.3 7.1 6.6 0.0 6.9 7 0 0 7 7 7 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 001043051.1_18529001_1 - 0.004 17.2 1.2 11 6.2 0.0 5.3 7 0 0 7 7 6 0 Natural killer cell receptor 2B4 LAX PF15681.3 001043051.1_18529001_1 - 0.015 13.9 0.0 0.031 12.8 0.0 1.5 1 0 0 1 1 1 0 Lymphocyte activation family X C2-set PF05790.13 001043051.1_18529001_1 - 0.02 15.0 0.0 41 4.3 0.0 4.9 5 0 0 5 5 5 0 Immunoglobulin C2-set domain ASH PF15780.3 001043051.1_18529001_1 - 0.1 12.7 2.8 2.3 8.3 0.3 3.1 3 0 0 3 3 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin 14-3-3 PF00244.18 001014515.2_18524001_2 - 5.7e-108 359.4 4.1 7.6e-108 359.0 4.1 1.2 1 0 0 1 1 1 1 14-3-3 protein RabGAP-TBC PF00566.16 001042984.2_18524001_1 - 3.2e-25 88.9 0.9 3.2e-25 88.9 0.9 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DIM PF08194.10 137475.3_18521001_3 - 7.6e-17 61.1 1.1 1e-16 60.7 1.1 1.2 1 0 0 1 1 1 1 DIM protein Attacin_C PF03769.13 079022.3_18522001_3 - 7.8e-48 161.5 15.9 9.5e-46 154.7 6.7 2.2 1 1 1 2 2 2 2 Attacin, C-terminal region Attacin_N PF03768.13 079022.3_18522001_3 - 9.6e-30 102.4 19.9 6.7e-29 99.7 9.8 2.6 2 0 0 2 2 2 2 Attacin, N-terminal region SH3_9 PF14604.4 165762.3_18524001_1 - 2.4e-40 136.0 0.1 1.5e-16 59.9 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.26 165762.3_18524001_1 - 1.6e-37 126.7 0.0 5.2e-12 45.0 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.15 165762.3_18524001_1 - 1.1e-27 95.4 0.1 1.3e-08 34.3 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.4 001144168.2_18526001_2 - 1.1e-39 133.9 0.1 2.6e-16 59.1 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.26 001144168.2_18526001_2 - 1.9e-37 126.5 1.4 9.1e-12 44.3 0.0 4.4 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.15 001144168.2_18526001_2 - 5.6e-27 93.1 0.1 2.3e-08 33.5 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.14 001144168.2_18526001_2 - 5.9e-11 41.7 0.3 2.8e-10 39.6 0.4 2.2 2 0 0 2 2 2 1 Sorbin homologous domain SH3_9 PF14604.4 001273931.1_18529001_3 - 4e-38 128.9 0.1 9.2e-16 57.3 0.1 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.26 001273931.1_18529001_3 - 1.8e-35 120.1 1.3 3.2e-11 42.5 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.15 001273931.1_18529001_3 - 2.6e-25 87.7 0.1 8.1e-08 31.7 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain DUF1777 PF08648.10 137995.3_18525001_1 - 2.6e-31 109.0 47.5 2e-30 106.2 47.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.7 137995.3_18525001_1 - 0.69 8.4 15.2 1.1 7.8 15.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LZ_Tnp_IS66 PF13007.5 137995.3_18525001_2 - 1.8 9.2 5.1 2.2 9.0 1.0 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain HTH_25 PF13413.4 001110886.2_18526001_1 - 0.44 10.3 5.0 0.72 9.6 0.3 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain PDZ PF00595.22 136839.3_18526001_3 - 0.0013 18.9 0.0 0.0045 17.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 136839.3_18526001_3 - 0.12 12.6 0.0 0.47 10.7 0.0 2.0 1 0 0 1 1 1 0 PDZ domain Ldl_recept_a PF00057.16 001273981.1_18529001_3 - 0.0016 18.5 6.3 0.006 16.7 6.3 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF4728 PF15860.3 001299452.1_18523001_1 - 0.0025 18.2 15.3 0.0025 18.2 15.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4728) Vpu PF00558.17 001299452.1_18523001_1 - 0.012 15.2 4.0 0.012 15.2 4.0 3.2 2 1 2 4 4 4 0 Vpu protein PBP_GOBP PF01395.20 166051.3_18524001_3 - 0.21 11.6 2.0 0.19 11.8 0.3 1.8 2 0 0 2 2 2 0 PBP/GOBP family Rif1_N PF12231.6 166120.2_18529001_1 - 1.2e-14 54.0 1.7 4.9e-14 52.0 0.3 2.4 2 1 1 3 3 3 1 Rap1-interacting factor 1 N terminal AAA_33 PF13671.4 001169725.2_18529001_2 - 2.9e-26 92.2 0.0 2.9e-26 92.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain SPRY PF00622.26 001169725.2_18529001_2 - 5.9e-13 48.9 0.0 5.9e-13 48.9 0.0 2.6 2 1 0 2 2 2 1 SPRY domain SAP PF02037.25 001169725.2_18529001_2 - 1.2e-12 47.2 0.5 2.2e-12 46.3 0.5 1.5 1 0 0 1 1 1 1 SAP domain Zeta_toxin PF06414.10 001169725.2_18529001_2 - 0.0023 17.1 1.8 0.0029 16.8 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.4 001169725.2_18529001_2 - 0.08 13.3 0.1 0.08 13.3 0.1 2.8 3 1 0 3 3 3 0 AAA domain Roc PF08477.11 001169725.2_18529001_2 - 1.3 9.1 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MSV199 PF10553.7 166395.3_18522001_2 - 0.021 15.0 0.4 0.033 14.3 0.1 1.5 2 0 0 2 2 2 0 MSV199 domain Pox_F11 PF04943.10 166395.3_18522001_2 - 0.032 13.2 1.2 0.24 10.3 1.0 1.8 1 1 1 2 2 2 0 Poxvirus F11 protein HA2 PF04408.21 001299858.1_18529001_1 - 5.3e-14 52.3 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.14 001299858.1_18529001_1 - 3.9e-13 49.4 0.1 9.7e-13 48.1 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Ank_2 PF12796.5 001299858.1_18529001_1 - 0.0009 19.7 0.2 0.0032 17.9 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.28 001299858.1_18529001_1 - 0.0033 17.7 0.2 0.16 12.3 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.4 001299858.1_18529001_1 - 0.01 16.1 0.0 3.2 8.5 0.0 3.6 2 0 0 2 2 2 0 Ankyrin repeat OS-D PF03392.11 166649.2_18521001_2 - 2.4e-17 62.7 0.6 3.2e-17 62.3 0.6 1.1 1 0 0 1 1 1 1 Insect pheromone-binding family, A10/OS-D Ank_2 PF12796.5 001299816.2_18524001_1 - 3.3e-11 43.5 0.1 5.9e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001299816.2_18524001_1 - 1.2e-05 25.6 0.0 0.013 16.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001299816.2_18524001_1 - 5.1e-05 23.2 0.1 0.37 11.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.4 001299816.2_18524001_1 - 0.00064 19.9 0.3 0.034 14.4 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.28 001299816.2_18524001_1 - 0.039 14.3 0.1 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat RIC3 PF15361.4 001169753.2_18525001_2 - 1.7e-28 99.7 0.0 5.4e-28 98.1 0.0 1.9 1 1 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 CENP-B_N PF04218.11 166494.3_18523001_1 - 2.8e-08 33.1 0.1 6.5e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.4 166494.3_18523001_1 - 9e-06 25.6 0.3 6.1e-05 22.9 0.6 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.4 166494.3_18523001_1 - 2.4e-05 23.8 0.4 5.5e-05 22.7 0.4 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.18 166494.3_18523001_1 - 0.00041 20.5 0.1 0.001 19.2 0.1 1.6 1 0 0 1 1 1 1 Transposase Sigma70_r4_2 PF08281.10 166494.3_18523001_1 - 0.0057 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.4 166494.3_18523001_1 - 0.019 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.4 166494.3_18523001_1 - 0.024 14.5 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r4 PF04545.14 166494.3_18523001_1 - 0.062 12.7 0.5 0.16 11.4 0.2 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Terminase_5 PF06056.10 166494.3_18523001_1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) GerE PF00196.17 166494.3_18523001_1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF508 PF04370.10 001043079.2_18525001_1 - 4.7 6.8 15.1 0.039 13.5 6.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Pkinase PF00069.23 001043079.2_18525001_3 - 1.3e-66 224.6 0.6 3.1e-66 223.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001043079.2_18525001_3 - 5.7e-32 110.9 0.3 1.3e-31 109.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.20 001043079.2_18525001_3 - 1e-14 54.0 11.1 1.9e-14 53.1 11.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.22 001043079.2_18525001_3 - 7.9e-06 26.3 1.5 2.1e-05 25.0 1.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.4 001043079.2_18525001_3 - 3.2e-05 23.3 0.0 3.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001043079.2_18525001_3 - 0.079 12.7 3.8 0.082 12.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family PHD PF00628.27 001043079.2_18525001_3 - 0.5 10.2 6.0 1.3 8.9 6.0 1.7 1 0 0 1 1 1 0 PHD-finger Pex14_N PF04695.11 001043079.2_18525001_3 - 2.2 8.8 15.8 5.6 7.6 15.8 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_L34 PF00468.15 001043087.2_18521001_1 - 2.6e-15 55.9 0.2 4.3e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 YjcZ PF13990.4 001043087.2_18521001_1 - 0.074 12.3 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 YjcZ-like protein zf-H2C2_2 PF13465.4 001299450.1_18529001_1 - 0.0028 17.9 6.3 0.0033 17.7 0.5 3.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.4 001299450.1_18529001_1 - 0.012 16.2 0.7 0.012 16.2 0.7 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.24 001299450.1_18529001_1 - 0.022 15.1 1.0 0.022 15.1 1.0 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Caudo_TAP PF02413.15 001299450.1_18529001_2 - 1.1 9.4 7.9 2.7 8.1 7.9 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK CAMSAP_CKK PF08683.9 001274124.1_18529001_2 - 1.3e-50 170.4 0.1 2.5e-50 169.5 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.6 001274124.1_18529001_2 - 4e-29 100.1 0.8 1e-28 98.9 0.1 2.1 2 0 0 2 2 2 1 CAMSAP CH domain CAMSAP_CC1 PF17095.3 001274124.1_18529001_2 - 2.2e-19 68.9 4.7 2.2e-19 68.9 4.7 3.1 2 1 0 2 2 2 1 Spectrin-binding region of Ca2+-Calmodulin CH PF00307.29 001274124.1_18529001_2 - 1.6e-05 24.9 0.0 9.5e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain NAD_kinase PF01513.19 001103832.3_18524001_2 - 3.3e-65 220.0 0.0 4.7e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.22 001103832.3_18524001_2 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PEN-2 PF10251.7 001299637.1_18523001_3 - 2.7e-39 133.3 4.4 2.7e-39 133.3 4.4 1.6 2 0 0 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase I-set PF07679.14 001299875.1_18529001_1 - 0 1047.4 11.9 1.6e-18 66.4 0.1 21.6 22 0 0 22 22 21 21 Immunoglobulin I-set domain Ig_3 PF13927.4 001299875.1_18529001_1 - 1.3e-211 685.7 0.6 3.8e-11 43.3 0.0 21.8 21 0 0 21 21 21 21 Immunoglobulin domain Ig_2 PF13895.4 001299875.1_18529001_1 - 8.5e-105 343.1 3.9 5.5e-06 26.5 0.0 22.0 20 2 1 21 21 21 17 Immunoglobulin domain Pkinase PF00069.23 001299875.1_18529001_1 - 9.6e-93 310.2 0.0 4.8e-49 167.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain ig PF00047.23 001299875.1_18529001_1 - 2.3e-77 255.1 1.1 4e-05 23.6 0.0 19.2 19 0 0 19 19 19 13 Immunoglobulin domain V-set PF07686.15 001299875.1_18529001_1 - 5.3e-50 168.0 13.1 0.0005 20.1 0.0 22.2 19 7 1 20 20 19 10 Immunoglobulin V-set domain Pkinase_Tyr PF07714.15 001299875.1_18529001_1 - 5.7e-49 166.6 0.0 1.4e-23 83.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase C2-set_2 PF08205.10 001299875.1_18529001_1 - 1.7e-21 76.0 0.5 2.5 8.1 0.0 16.5 19 0 0 19 19 18 2 CD80-like C2-set immunoglobulin domain fn3 PF00041.19 001299875.1_18529001_1 - 2.7e-21 75.6 0.0 5e-12 45.9 0.0 3.7 3 0 0 3 3 3 2 Fibronectin type III domain Receptor_2B4 PF11465.6 001299875.1_18529001_1 - 4.1e-17 62.2 13.5 0.52 10.4 0.1 16.1 17 1 1 18 18 18 2 Natural killer cell receptor 2B4 Izumo-Ig PF16706.3 001299875.1_18529001_1 - 6.5e-08 32.4 11.1 7.3 6.6 0.1 10.9 13 0 0 13 13 13 1 Izumo-like Immunoglobulin domain Herpes_gE PF02480.14 001299875.1_18529001_1 - 1.4e-05 24.0 7.6 6.7 5.2 0.0 8.0 10 1 0 11 11 11 1 Alphaherpesvirus glycoprotein E RhoGEF PF00621.18 001299875.1_18529001_1 - 4.5e-05 23.6 0.4 0.00012 22.2 0.4 1.7 1 0 0 1 1 1 1 RhoGEF domain Kdo PF06293.12 001299875.1_18529001_1 - 0.00021 20.6 0.3 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pur_ac_phosph_N PF16656.3 001299875.1_18529001_1 - 0.0019 18.6 6.3 0.029 14.8 0.0 4.2 4 0 0 4 4 2 1 Purple acid Phosphatase, N-terminal domain DUF1831 PF08866.8 001299875.1_18529001_1 - 0.064 13.6 0.1 0.25 11.7 0.1 2.0 1 0 0 1 1 1 0 Putative amino acid metabolism DUF1214 PF06742.9 001299875.1_18529001_1 - 0.12 12.7 0.0 3.2 8.1 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1214) Peptidase_A4 PF01828.15 001299875.1_18529001_1 - 0.13 11.6 4.4 0.14 11.5 0.4 2.9 3 1 0 4 4 4 0 Peptidase A4 family V-set_CD47 PF08204.9 001299875.1_18529001_1 - 0.34 10.8 20.8 4.1 7.3 0.2 8.6 10 0 0 10 10 9 0 CD47 immunoglobulin-like domain DUF1091 PF06477.11 001032235.1_18522001_1 - 6.6e-10 39.2 0.1 1e-09 38.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1091) DUF1091 PF06477.11 001032228.1_18522001_1 - 2.1e-05 24.8 0.0 3.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1091) FlxA PF14282.4 001038853.3_18522001_2 - 0.0075 16.1 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 2 FlxA-like protein DUF753 PF05444.10 001038874.3_18522001_3 - 2e-23 82.9 28.1 2e-23 82.9 28.1 1.7 1 1 0 2 2 2 1 Protein of unknown function (DUF753) Sporozoite_P67 PF05642.9 001038874.3_18522001_3 - 0.062 11.3 5.2 0.061 11.3 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SOG2 PF10428.7 001038874.3_18522001_3 - 0.1 11.7 12.0 0.13 11.4 12.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1180 PF06679.10 001038874.3_18522001_3 - 0.6 10.4 5.3 1.1 9.5 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Menin PF05053.11 001038874.3_18522001_3 - 1.1 7.4 4.1 1.3 7.2 2.9 1.6 2 0 0 2 2 2 0 Menin Anillin_N PF16018.3 001038874.3_18522001_3 - 6.5 7.3 10.1 59 4.2 0.0 3.2 3 1 0 3 3 3 0 Anillin N-terminus Ufm1 PF03671.12 001103884.4_18522001_1 - 3.4e-41 139.1 0.1 4.8e-41 138.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein CBM_14 PF01607.22 001103783.2_18525001_1 - 1e-10 41.5 1.2 5.5e-10 39.1 1.2 2.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain zf-GRF PF06839.10 001103783.2_18525001_1 - 0.051 13.6 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 GRF zinc finger DUF4728 PF15860.3 001103807.1_18522001_3 - 0.012 16.0 10.9 0.013 16.0 9.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4728) GPHH PF16905.3 001274246.2_18529001_1 - 8.5e-06 25.4 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ion_trans PF00520.29 001274246.2_18529001_2 - 6.5e-226 745.9 101.1 3.7e-63 212.9 25.4 4.3 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.10 001274246.2_18529001_2 - 4.3e-07 28.8 83.5 4e-05 22.3 5.1 8.7 7 3 3 10 10 10 7 Polycystin cation channel NKAIN PF05640.12 001169826.3_18524001_3 - 1.2e-85 285.8 5.2 1.6e-85 285.3 5.2 1.1 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein 5-FTHF_cyc-lig PF01812.18 001103962.4_18522001_2 - 8.6e-46 156.0 0.1 1.2e-45 155.5 0.1 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF2070 PF09843.7 001103752.1_18522001_1 - 0.63 8.1 10.9 0.83 7.7 10.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DM4_12 PF07841.11 001103842.2_18522001_2 - 8e-20 71.2 0.0 1.5e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 DM4/DM12 family DM4_12 PF07841.11 001103843.2_18522001_2 - 1.4e-16 60.8 1.4 1.8e-16 60.4 0.0 1.9 2 0 0 2 2 2 1 DM4/DM12 family SPT6_acidic PF14632.4 001103843.2_18522001_2 - 0.18 12.3 14.4 1.9 9.0 1.6 2.2 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Spem1 PF15670.3 001103843.2_18522001_2 - 0.46 9.9 6.4 0.68 9.3 6.4 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 PT PF04886.10 001202029.2_18525001_1 - 0.08 12.4 1.2 0.16 11.4 1.2 1.4 1 0 0 1 1 1 0 PT repeat BPL_LplA_LipB PF03099.17 001202029.2_18525001_2 - 0.0014 18.4 0.0 0.0045 16.7 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family TB2_DP1_HVA22 PF03134.17 001202059.2_18526001_2 - 7.1e-27 93.0 9.3 1.5e-26 92.0 9.3 1.6 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4089 PF13318.4 001202059.2_18526001_2 - 0.062 13.6 0.2 0.99 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) PA14_2 PF10528.7 001202059.2_18526001_2 - 0.1 12.8 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 GLEYA domain DUF2306 PF10067.7 001202059.2_18526001_2 - 0.15 12.1 0.8 0.5 10.4 1.3 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) Pkinase PF00069.23 001169580.2_18525001_1 - 3.3e-71 239.6 0.0 5.4e-71 238.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001169580.2_18525001_1 - 4.9e-30 104.5 0.0 8.5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.17 001169580.2_18525001_1 - 2.3e-19 69.7 8.6 5.9e-19 68.3 8.6 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.27 001169580.2_18525001_1 - 4.7e-07 30.1 0.1 9.3e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 PH domain Oxidored_molyb PF00174.17 001169580.2_18525001_1 - 0.0053 16.2 0.1 0.03 13.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Kinase-like PF14531.4 001169580.2_18525001_1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.12 001169580.2_18525001_1 - 0.076 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.14 001015095.4_18526001_3 - 6.5e-42 143.6 32.0 1.1e-41 142.8 30.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.14 001276229.1_18525001_2 - 3.8e-42 144.4 32.6 5.9e-42 143.7 30.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily CENP-F_leu_zip PF10473.7 001201533.1_18525001_2 - 0.55 10.1 10.2 0.42 10.5 5.2 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.10 001201533.1_18525001_2 - 2.6 7.9 17.0 5.1 7.0 2.0 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) CG-1 PF03859.14 001144153.2_18529001_1 - 2.2e-43 146.6 1.5 2.2e-43 146.6 1.5 2.9 2 0 0 2 2 2 1 CG-1 domain Ank_2 PF12796.5 001144153.2_18529001_1 - 2.1e-08 34.5 0.4 0.00021 21.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001144153.2_18529001_1 - 0.0011 19.2 0.5 5.6 7.5 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.4 001144153.2_18529001_1 - 0.0032 17.7 0.5 0.26 11.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.4 001144153.2_18529001_1 - 0.015 15.7 2.4 11 6.8 0.1 3.9 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.4 001144153.2_18529001_1 - 0.071 13.6 0.2 2.8 8.5 0.1 3.3 1 1 2 3 3 3 0 Ankyrin repeats (many copies) IQ PF00612.25 001144153.2_18529001_1 - 0.12 12.1 20.7 0.19 11.5 0.2 4.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif DUF4820 PF16091.3 001144232.4_18524001_1 - 4.9e-77 258.2 0.3 4.9e-77 258.2 0.3 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4820) SEEEED PF14797.4 001144232.4_18524001_1 - 2.7 8.0 26.6 6.5 6.8 26.6 1.7 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex HGTP_anticodon2 PF12745.5 001144232.4_18524001_1 - 9.5 5.4 12.2 0.31 10.3 5.5 1.8 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Trypan_PARP PF05887.9 001144232.4_18524001_2 - 0.86 9.5 6.6 1.6 8.7 6.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Flavoprotein PF02441.17 001169772.2_18523001_3 - 1.8e-46 157.7 0.0 2.2e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein CHCH PF06747.11 001169772.2_18523001_3 - 1.8e-05 24.6 6.1 3.1e-05 23.8 6.1 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.3 001169772.2_18523001_3 - 0.00048 20.0 2.8 0.00094 19.0 2.8 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.11 001169772.2_18523001_3 - 0.039 13.5 1.5 0.066 12.8 1.5 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) AAA_23 PF13476.4 001169798.2_18522001_2 - 0.008 16.6 8.2 0.011 16.1 8.2 1.1 1 0 0 1 1 1 1 AAA domain Prominin PF05478.9 001169798.2_18522001_2 - 0.073 10.9 3.2 0.098 10.5 3.2 1.0 1 0 0 1 1 1 0 Prominin Paralemmin PF03285.13 001169798.2_18522001_2 - 0.8 9.1 6.7 1.1 8.7 6.7 1.2 1 0 0 1 1 1 0 Paralemmin DUF342 PF03961.11 001169798.2_18522001_2 - 3.1 6.2 9.1 3.7 5.9 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TB2_DP1_HVA22 PF03134.17 001274215.1_18523001_2 - 5.3e-27 93.4 9.3 5.3e-27 93.4 9.3 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family URO-D PF01208.15 001274215.1_18523001_2 - 0.071 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Pou PF00157.15 001299264.1_18529001_2 - 1.9e-28 98.1 0.1 4.6e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001299264.1_18529001_2 - 4.3e-16 58.3 0.2 1e-15 57.2 0.2 1.7 1 0 0 1 1 1 1 Homeobox domain DUF3915 PF13054.4 001299264.1_18529001_2 - 0.0024 17.7 4.9 0.0024 17.7 4.9 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3915) DUF2722 PF10846.6 001273935.1_18529001_1 - 0.00043 19.2 2.6 0.00058 18.8 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) BK_channel_a PF03493.16 001273935.1_18529001_2 - 9.4e-29 99.4 0.0 3e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.14 001273935.1_18529001_2 - 8.9e-09 35.1 2.9 8.9e-09 35.1 2.9 1.9 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.29 001273935.1_18529001_2 - 0.055 12.6 7.3 0.12 11.4 7.3 1.5 1 0 0 1 1 1 0 Ion transport protein CENP-B_dimeris PF09026.8 001273935.1_18529001_2 - 0.22 11.8 0.5 2.7 8.3 0.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF508 PF04370.10 001274055.1_18529001_1 - 0.016 14.8 6.5 0.049 13.2 6.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Pkinase PF00069.23 001274055.1_18529001_3 - 1.9e-66 224.0 0.3 1.3e-65 221.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001274055.1_18529001_3 - 2.6e-31 108.7 0.2 5.1e-31 107.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.20 001274055.1_18529001_3 - 5e-14 51.8 11.1 5e-14 51.8 11.1 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.22 001274055.1_18529001_3 - 1.4e-07 32.0 1.5 4.5e-07 30.3 1.5 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.21 001274055.1_18529001_3 - 0.25 11.1 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family TFIIA PF03153.11 001274055.1_18529001_3 - 5 6.9 49.9 1.8 8.3 31.0 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.23 001274056.2_18526001_2 - 1.7e-66 224.1 0.2 5.9e-66 222.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001274056.2_18526001_2 - 5.9e-32 110.8 0.1 2.4e-31 108.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.20 001274056.2_18526001_2 - 1.5e-14 53.5 11.1 2.9e-14 52.6 11.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.22 001274056.2_18526001_2 - 1.1e-07 32.2 1.5 2.6e-07 31.1 1.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.21 001274056.2_18526001_2 - 0.14 11.9 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family TFIIA PF03153.11 001274056.2_18526001_2 - 0.47 10.2 26.5 0.7 9.7 26.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.27 001274056.2_18526001_2 - 0.6 9.9 6.0 1.8 8.4 6.0 1.9 1 0 0 1 1 1 0 PHD-finger Pex14_N PF04695.11 001274056.2_18526001_2 - 1.3 9.6 15.1 3 8.4 15.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.4 001274056.2_18526001_2 - 7.4 4.2 20.2 10 3.7 20.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Erf4 PF10256.7 001274024.2_18528001_3 - 0.12 12.4 0.4 0.44 10.5 0.4 2.0 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family C1_1 PF00130.20 001299524.1_18529001_1 - 3.9e-09 36.1 4.7 9.3e-09 34.9 4.7 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.3 001299524.1_18529001_1 - 0.073 13.1 5.7 0.062 13.3 2.0 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger LRR_8 PF13855.4 001103864.3_18529001_3 - 6e-96 314.1 76.8 2.3e-14 52.7 3.7 10.7 5 4 6 11 11 11 10 Leucine rich repeat LRR_5 PF13306.4 001103864.3_18529001_3 - 1.7e-37 128.1 9.8 6.3e-07 29.3 0.1 5.4 4 1 1 5 5 5 5 Leucine rich repeats (6 copies) LRR_4 PF12799.5 001103864.3_18529001_3 - 1.3e-35 120.5 75.6 6e-05 23.2 2.7 13.4 8 3 3 13 13 13 12 Leucine Rich repeats (2 copies) LRRNT PF01462.16 001103864.3_18529001_3 - 5.8e-34 115.0 48.8 2e-10 39.9 2.1 8.0 6 0 0 6 6 6 4 Leucine rich repeat N-terminal domain Laminin_G_1 PF00054.21 001103864.3_18529001_3 - 3.2e-32 111.3 0.0 6.7e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.25 001103864.3_18529001_3 - 1.5e-30 105.0 141.8 1.5e-07 31.5 6.0 10.5 12 0 0 12 12 9 7 EGF-like domain Laminin_G_2 PF02210.22 001103864.3_18529001_3 - 3.7e-22 79.1 0.1 2.9e-21 76.2 0.0 2.3 2 0 0 2 2 2 1 Laminin G domain LRRCT PF01463.22 001103864.3_18529001_3 - 2.4e-19 68.1 8.2 3.9e-05 23.7 0.1 5.6 4 0 0 4 4 4 4 Leucine rich repeat C-terminal domain LRR_9 PF14580.4 001103864.3_18529001_3 - 6.7e-18 64.7 30.4 0.00087 18.7 0.6 7.0 4 3 3 7 7 7 6 Leucine-rich repeat hEGF PF12661.5 001103864.3_18529001_3 - 3.1e-14 52.9 113.3 1.7e-07 31.5 3.7 10.5 11 0 0 11 11 8 6 Human growth factor-like EGF LRR_1 PF00560.31 001103864.3_18529001_3 - 3.1e-05 23.7 58.0 4.2 8.1 0.0 17.1 16 2 0 16 16 16 2 Leucine Rich Repeat EGF_3 PF12947.5 001103864.3_18529001_3 - 0.0016 18.4 3.7 0.0016 18.4 3.7 9.6 7 2 2 9 9 7 4 EGF domain TRPM_tetra PF16519.3 001144201.2_18529001_1 - 9e-19 67.2 6.2 1.6e-18 66.4 6.2 1.4 1 0 0 1 1 1 1 Tetramerisation domain of TRPM Ion_trans PF00520.29 001144201.2_18529001_1 - 2.8e-16 59.4 14.4 6.1e-16 58.3 14.4 1.6 1 0 0 1 1 1 1 Ion transport protein MCPsignal PF00015.19 001144201.2_18529001_1 - 0.2 11.3 2.4 0.4 10.3 2.4 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain XhlA PF10779.7 001144201.2_18529001_1 - 0.56 10.3 5.2 1.2 9.2 5.2 1.6 1 0 0 1 1 1 0 Haemolysin XhlA DUF3421 PF11901.6 001299437.1_18524001_3 - 9.3e-75 247.9 11.0 1.1e-32 112.3 0.5 4.7 2 2 4 6 6 6 6 Protein of unknown function (DUF3421) OppC_N PF12911.5 001299696.1_18521001_2 - 0.092 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Zip PF02535.20 136733.5_18522001_2 - 0.00014 21.1 0.5 0.00016 20.9 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.12 136733.5_18522001_2 - 0.0038 17.5 11.4 0.0054 17.1 11.4 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 DUF1510 PF07423.9 136733.5_18522001_2 - 0.0063 15.8 23.2 0.008 15.5 23.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DDHD PF02862.15 136733.5_18522001_2 - 0.012 15.7 5.3 0.017 15.1 5.3 1.2 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.9 136733.5_18522001_2 - 0.12 12.3 40.1 0.16 12.0 40.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SID-1_RNA_chan PF13965.4 136733.5_18522001_2 - 0.29 9.4 1.8 0.39 9.0 1.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PTPRCAP PF15713.3 136733.5_18522001_2 - 0.32 11.2 16.7 0.41 10.8 16.7 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF913 PF06025.10 136733.5_18522001_2 - 0.33 9.7 7.1 0.42 9.4 7.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.3 136733.5_18522001_2 - 0.67 9.1 7.4 0.96 8.6 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Spt20 PF12090.6 136733.5_18522001_2 - 0.8 9.1 9.2 1.1 8.7 9.2 1.1 1 0 0 1 1 1 0 Spt20 family HemX PF04375.12 136733.5_18522001_2 - 0.85 8.7 6.8 1.2 8.3 6.8 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SLC12 PF03522.13 136733.5_18522001_2 - 1.5 7.6 12.6 1.9 7.3 12.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.9 136733.5_18522001_2 - 1.5 8.0 18.1 2.1 7.6 18.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.17 136733.5_18522001_2 - 2 6.1 13.0 2.6 5.7 13.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.15 136733.5_18522001_2 - 2.1 7.2 6.3 2.8 6.7 6.3 1.1 1 0 0 1 1 1 0 CLN3 protein DUF789 PF05623.10 136733.5_18522001_2 - 2.1 7.8 8.5 2.8 7.4 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) DNA_pol_phi PF04931.11 136733.5_18522001_2 - 2.2 6.2 15.2 2.8 5.8 15.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi MCM_bind PF09739.7 136733.5_18522001_2 - 2.2 6.5 12.2 2.8 6.2 12.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Afi1 PF07792.10 136733.5_18522001_2 - 3.8 7.9 12.5 5.6 7.3 12.5 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking O-antigen_lig PF13425.4 136733.5_18522001_2 - 4.4 5.8 7.5 6.2 5.4 7.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TRAP_alpha PF03896.14 136733.5_18522001_2 - 5.7 5.9 8.2 8.1 5.4 8.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MAP17 PF15807.3 136733.5_18522001_2 - 5.9 7.0 18.5 8.2 6.5 18.5 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CP2 PF04516.13 001347799.1_18529001_1 - 1.6e-60 204.2 13.3 1.2e-51 175.1 0.0 2.7 3 0 0 3 3 3 2 CP2 transcription factor SAM_2 PF07647.15 001347799.1_18529001_1 - 0.00081 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001347799.1_18529001_1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) rve PF00665.24 074072.2_18525120_3 - 0.012 15.7 0.0 0.047 13.7 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Ser_hydrolase PF06821.11 073834.1_18522120_1 - 0.069 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF5133 PF17196.2 124447.1_18522120_2 - 0.06 13.4 0.1 0.098 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF5133) FSAP_sig_propep PF03032.13 073854.1_18523120_3 - 4.8 7.2 7.0 8.5 6.4 7.0 1.3 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide FSAP_sig_propep PF03032.13 073855.1_18522120_3 - 3.4 7.7 7.8 5.7 6.9 7.8 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide ECR1_N PF14382.4 124481.1_18522120_2 - 0.056 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Trp_oprn_chp PF09534.8 124489.1_18523120_2 - 0.26 10.9 12.1 0.4 10.3 12.1 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) HigB_toxin PF09907.7 124496.1_18523120_3 - 0.066 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system TAF8_C PF10406.7 124509.1_18522120_2 - 8.2 6.9 8.4 9.3 6.8 0.5 2.4 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term FAM27 PF15832.3 124543.1_18526120_1 - 8.3 6.9 12.5 14 6.1 12.5 1.3 1 0 0 1 1 1 0 FAM27 D and E protein family IGFL PF14653.4 124559.1_18529120_1 - 8.2 6.3 11.7 28 4.6 0.3 3.4 3 0 0 3 3 3 0 Insulin growth factor-like family B9-C2 PF07162.9 073879.1_18523120_3 - 0.032 14.3 0.2 0.06 13.4 0.2 1.3 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein KRTAP PF11759.6 133126.1_18529120_1 - 0.012 16.0 6.7 0.041 14.3 6.7 1.8 1 0 0 1 1 1 0 Keratin-associated matrix KRTAP PF11759.6 124572.1_18529120_1 - 0.36 11.3 12.2 0.028 14.8 6.7 2.0 2 0 0 2 2 2 0 Keratin-associated matrix BHD_1 PF10403.7 124580.1_18521120_3 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 COA2 PF17051.3 048127.1_18523120_2 - 0.072 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 STOP PF05217.10 048127.1_18523120_2 - 0.86 9.8 7.6 0.85 9.8 3.2 2.7 2 0 0 2 2 2 0 STOP protein C1_2 PF03107.14 124593.1_18521120_1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.6 2 1 0 2 2 2 0 C1 domain UPF0547 PF10571.7 124598.1_18521120_3 - 0.08 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 CCER1 PF15482.4 124603.1_18523120_3 - 0.073 12.8 1.2 0.11 12.2 1.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 DUF3446 PF11928.6 124615.1_18522120_3 - 0.016 15.3 1.6 0.031 14.5 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Dicty_REP PF05086.10 124615.1_18522120_3 - 0.18 9.6 3.6 0.22 9.3 3.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.7 124615.1_18522120_3 - 0.69 7.8 3.7 0.83 7.6 3.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Lamp PF01299.15 124615.1_18522120_3 - 2 7.7 8.7 2.7 7.3 8.7 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) SSP160 PF06933.9 124615.1_18522120_3 - 2.8 5.9 12.8 3.5 5.6 12.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sigma70_r4_2 PF08281.10 124619.1_18521120_3 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 PT PF04886.10 124628.1_18522120_1 - 0.27 10.7 8.5 0.27 10.7 4.8 2.1 2 0 0 2 2 2 0 PT repeat PT PF04886.10 124628.1_18522120_2 - 7.4 6.1 13.6 0.26 10.8 7.5 1.6 2 0 0 2 2 2 0 PT repeat PT PF04886.10 124628.1_18522120_3 - 0.01 15.2 1.3 0.019 14.4 1.3 1.4 1 0 0 1 1 1 0 PT repeat PT PF04886.10 124641.1_18522120_1 - 0.029 13.8 2.7 0.058 12.8 2.7 1.4 1 0 0 1 1 1 0 PT repeat PT PF04886.10 124641.1_18522120_3 - 0.028 13.8 2.9 0.11 12.0 0.4 2.7 2 0 0 2 2 2 0 PT repeat APC_15aa PF05972.9 124641.1_18522120_3 - 0.15 12.2 2.7 0.44 10.8 0.4 2.4 1 1 0 2 2 2 0 APC 15 residue motif Ribosomal_S19 PF00203.19 124670.1_18521120_2 - 0.1 12.4 2.4 8.6 6.2 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S19 PAN_2 PF08276.9 124671.1_18522120_2 - 2.2 8.3 7.4 0.48 10.4 1.9 2.4 2 0 0 2 2 2 0 PAN-like domain CAP_N PF01213.17 048186.1_18523120_2 - 0.38 10.1 2.6 0.57 9.5 2.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNCAIP_SNCA_bd PF16700.3 124672.1_18522120_1 - 0.16 11.6 0.3 0.32 10.6 0.3 1.4 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain AP-5_subunit_s1 PF15001.4 124673.1_18523120_3 - 0.077 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Ectatomin PF06457.9 073895.1_18522120_2 - 0.074 12.9 1.6 0.12 12.2 1.6 1.3 1 0 0 1 1 1 0 Ectatomin zf-HYPF PF07503.10 048190.1_18523120_2 - 0.13 11.9 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 HypF finger RNA_pol_Rpb1_R PF05001.11 133136.1_18523120_1 - 0.073 13.3 0.7 0.19 12.0 0.7 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat Corona_nucleoca PF00937.16 133136.1_18523120_2 - 0.021 13.7 2.4 0.03 13.2 2.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1242 PF06842.10 124721.1_18521120_3 - 0.52 10.0 5.0 1.3 8.7 5.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) TMEM131_like PF12371.6 124722.1_18521120_1 - 0.028 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 131-like OmdA PF13376.4 124723.1_18523120_2 - 0.022 14.6 1.3 0.039 13.8 1.3 1.3 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Ribosomal_60s PF00428.17 124728.1_18523120_1 - 0.36 11.3 10.9 3.6 8.1 2.5 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3042 PF11240.6 124728.1_18523120_1 - 0.4 10.6 0.1 0.4 10.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) SUIM_assoc PF16619.3 124728.1_18523120_2 - 0.11 12.4 8.5 0.5 10.4 0.9 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1348 PF07080.9 048202.1_18523120_2 - 0.21 11.4 0.6 0.48 10.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) SpoVT_C PF15714.3 048202.1_18523120_2 - 0.27 11.2 0.7 0.78 9.7 0.2 1.7 1 1 1 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor Gal-bind_lectin PF00337.20 134644.4_18523001_3 - 5.3e-55 184.5 0.0 4.6e-27 94.0 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin ABC2_membrane PF01061.22 164365.2_18526001_1 - 5.2e-33 114.1 30.6 5.2e-33 114.1 30.6 2.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.25 164365.2_18526001_1 - 2.8e-26 92.5 0.0 4.3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.4 164365.2_18526001_1 - 6.9e-07 29.2 0.1 0.002 17.9 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF258 PF03193.14 164365.2_18526001_1 - 0.00026 20.8 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.17 164365.2_18526001_1 - 0.00032 20.1 0.0 0.011 15.0 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.4 164365.2_18526001_1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.4 164365.2_18526001_1 - 0.0019 18.6 0.1 0.0019 18.6 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.4 164365.2_18526001_1 - 0.0052 16.4 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.4 164365.2_18526001_1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.4 164365.2_18526001_1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.4 164365.2_18526001_1 - 0.035 14.2 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.4 164365.2_18526001_1 - 0.05 13.2 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.21 164365.2_18526001_1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.4 164365.2_18526001_1 - 0.12 12.4 0.0 1.2 9.2 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Phage_holin_3_6 PF07332.9 164365.2_18526001_1 - 0.25 11.2 4.8 0.89 9.5 0.0 2.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SPOC PF07744.11 079979.5_18529001_3 - 2.8e-34 118.1 0.1 2.8e-34 118.1 0.1 2.0 2 0 0 2 2 2 1 SPOC domain RRM_1 PF00076.20 079979.5_18529001_3 - 2.6e-24 84.7 0.4 1.1e-11 44.2 0.0 4.0 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 079979.5_18529001_3 - 0.051 13.4 0.1 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PI-PLC-X PF00388.17 205882.2_18529001_2 - 4.1e-61 204.7 0.0 1.9e-60 202.5 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.17 205882.2_18529001_2 - 3.6e-42 143.2 0.2 1e-41 141.8 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.9 205882.2_18529001_2 - 2.6e-17 62.9 0.0 1.2e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like PLC-beta_C PF08703.8 205882.2_18529001_2 - 4.7e-05 23.3 14.8 4.7e-05 23.3 14.8 2.2 2 0 0 2 2 2 1 PLC-beta C terminal LVIVD PF08309.9 205882.2_18529001_2 - 0.013 14.6 0.0 0.032 13.4 0.0 1.6 1 0 0 1 1 1 0 LVIVD repeat PH_12 PF16457.3 205882.2_18529001_2 - 0.073 13.5 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain COG5 PF10392.7 205882.2_18529001_2 - 5.5 7.0 9.0 0.16 12.0 1.8 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF4816 PF16086.3 205882.2_18529001_3 - 0.22 11.4 2.6 0.54 10.2 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4816) DRMBL PF07522.12 001144290.2_18525001_2 - 0.1 12.7 0.4 3.5 7.7 0.2 2.4 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase Homeobox PF00046.27 001144290.2_18525001_3 - 7.3e-21 73.6 4.1 1.3e-20 72.9 4.1 1.4 1 0 0 1 1 1 1 Homeobox domain Rrn6 PF10214.7 001014454.2_18526001_3 - 4e-06 25.5 19.4 4e-06 25.5 19.4 2.2 1 1 1 2 2 2 1 RNA polymerase I-specific transcription-initiation factor MIP-T3 PF10243.7 001014454.2_18526001_3 - 0.013 14.2 52.9 0.019 13.6 52.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Med26 PF08711.9 001014454.2_18526001_3 - 0.014 15.3 0.2 0.032 14.1 0.2 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Tfb4 PF03850.12 134730.3_18522001_1 - 1.9e-96 322.6 2.7 2.4e-96 322.3 2.7 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Ig_3 PF13927.4 134748.4_18529001_1 - 1.4e-73 243.3 0.0 1.4e-15 57.6 0.0 6.1 6 0 0 6 6 6 5 Immunoglobulin domain I-set PF07679.14 134748.4_18529001_1 - 4.9e-71 234.7 0.0 2.3e-14 53.1 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.4 134748.4_18529001_1 - 2.8e-44 149.2 0.2 2.5e-12 46.8 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin domain ig PF00047.23 134748.4_18529001_1 - 3.4e-36 123.2 0.0 6.7e-08 32.5 0.0 6.3 5 1 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.19 134748.4_18529001_1 - 3.2e-25 88.2 0.0 5.9e-09 36.0 0.0 3.5 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.15 134748.4_18529001_1 - 2.9e-15 56.2 0.9 0.23 11.5 0.0 8.8 5 4 0 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.10 134748.4_18529001_1 - 2.1e-11 43.6 0.2 0.015 15.3 0.0 5.2 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Sp38 PF07354.10 134748.4_18529001_1 - 0.0031 16.3 0.0 0.79 8.4 0.0 2.2 2 0 0 2 2 2 2 Zona-pellucida-binding protein (Sp38) BiPBP_C PF06832.10 134748.4_18529001_1 - 0.0092 15.9 0.0 0.51 10.3 0.0 2.8 2 0 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family Izumo-Ig PF16706.3 134748.4_18529001_1 - 0.075 13.0 0.1 3.2 7.7 0.0 3.1 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Lectin_C PF00059.19 134785.3_18522001_1 - 2.8e-15 56.8 0.2 5.1e-15 56.0 0.2 1.4 1 0 0 1 1 1 1 Lectin C-type domain Xlink PF00193.15 134785.3_18522001_1 - 0.12 12.7 0.2 2.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Extracellular link domain Bax1-I PF01027.18 001032047.3_18522001_3 - 7.4e-28 97.7 34.9 8.6e-28 97.5 34.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 RRM_1 PF00076.20 057589.3_18527001_1 - 6.6e-63 208.3 0.2 5.2e-21 74.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 057589.3_18527001_1 - 8.9e-12 44.6 0.5 3.8e-05 23.2 0.0 3.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 057589.3_18527001_1 - 0.00062 19.4 0.7 0.019 14.7 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.3 057589.3_18527001_1 - 0.013 15.4 0.0 2 8.5 0.0 3.4 3 0 0 3 3 3 0 RNA recognition motif RRM_3 PF08777.9 057589.3_18527001_1 - 0.056 13.4 0.0 6.1 6.8 0.0 3.2 2 1 0 2 2 2 0 RNA binding motif RNA_bind PF08675.9 057589.3_18527001_1 - 0.067 13.1 0.0 2.9 7.9 0.0 3.1 3 0 0 3 3 3 0 RNA binding domain ADH_zinc_N_2 PF13602.4 134902.2_18523001_3 - 5.6e-18 66.1 0.0 9.3e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.24 134902.2_18523001_3 - 3.5e-10 39.7 0.1 2.3e-09 37.1 0.1 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.10 134902.2_18523001_3 - 1.4e-05 24.7 0.0 5.6e-05 22.8 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.15 134902.2_18523001_3 - 0.00069 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.19 134902.2_18523001_3 - 0.001 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.19 134902.2_18523001_3 - 0.011 15.0 0.3 0.016 14.3 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.4 134902.2_18523001_3 - 0.024 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_3 PF03447.14 134902.2_18523001_3 - 0.073 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain RasGEF PF00617.17 134909.3_18526001_1 - 2.4e-18 66.8 0.1 7.7e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.18 134909.3_18526001_1 - 5.4e-08 32.9 1.5 9e-07 29.0 0.3 2.7 2 1 0 2 2 2 1 RasGEF N-terminal motif ABC2_membrane PF01061.22 134924.2_18529001_3 - 1.3e-33 116.1 17.2 1.3e-33 116.1 17.2 1.7 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.25 134924.2_18529001_3 - 2.8e-29 102.2 0.4 2.5e-28 99.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.4 134924.2_18529001_3 - 3.8e-06 26.8 0.0 0.0083 15.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.17 134924.2_18529001_3 - 0.00042 19.7 0.1 0.33 10.2 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.4 134924.2_18529001_3 - 0.00044 19.8 0.9 0.0044 16.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.4 134924.2_18529001_3 - 0.0011 19.4 0.7 0.015 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.14 134924.2_18529001_3 - 0.0013 18.6 0.0 0.0013 18.6 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.4 134924.2_18529001_3 - 0.0078 16.5 1.4 0.012 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.4 134924.2_18529001_3 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.4 134924.2_18529001_3 - 0.017 15.1 1.5 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.21 134924.2_18529001_3 - 0.13 12.2 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.4 134924.2_18529001_3 - 0.15 12.5 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain MAT1 PF06391.11 134924.2_18529001_3 - 0.51 10.0 11.7 1.8 8.2 11.7 2.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Pkinase PF00069.23 058141.4_18528001_3 - 2.5e-70 236.7 0.0 6.6e-70 235.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 058141.4_18528001_3 - 2e-37 128.8 0.0 4.2e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.27 058141.4_18528001_3 - 4.9e-30 103.3 0.2 8.5e-19 67.2 0.1 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.4 058141.4_18528001_3 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ig_3 PF13927.4 078745.3_18529001_1 - 2.8e-76 252.0 17.3 2.2e-14 53.7 0.1 8.5 8 0 0 8 8 8 7 Immunoglobulin domain I-set PF07679.14 078745.3_18529001_1 - 1.9e-57 191.2 2.5 2.9e-09 36.7 0.0 9.1 7 2 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.4 078745.3_18529001_1 - 6.5e-57 189.7 7.3 2.8e-09 37.1 0.0 8.2 7 2 0 7 7 7 6 Immunoglobulin domain ig PF00047.23 078745.3_18529001_1 - 3.3e-47 158.4 1.9 4e-10 39.6 0.2 8.5 7 3 0 7 7 7 6 Immunoglobulin domain V-set PF07686.15 078745.3_18529001_1 - 4e-25 88.0 11.6 3.3e-05 23.9 0.0 10.0 7 4 2 9 9 9 6 Immunoglobulin V-set domain C2-set_2 PF08205.10 078745.3_18529001_1 - 2.7e-21 75.3 1.9 3e-07 30.3 0.0 6.3 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain fn3 PF00041.19 078745.3_18529001_1 - 4.7e-10 39.6 0.0 4e-09 36.6 0.0 2.6 2 0 0 2 2 2 1 Fibronectin type III domain C1-set PF07654.13 078745.3_18529001_1 - 7.5e-09 35.8 4.6 1.4 9.3 0.0 6.2 6 0 0 6 6 6 3 Immunoglobulin C1-set domain Ig_5 PF16681.3 078745.3_18529001_1 - 1.2e-06 28.7 0.2 1.1 9.6 0.0 6.7 8 0 0 8 8 8 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.3 078745.3_18529001_1 - 2.3e-05 24.5 1.0 0.9 9.8 0.0 6.3 7 0 0 7 7 7 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.9 078745.3_18529001_1 - 0.00057 19.7 5.0 1.3 8.8 0.1 5.0 3 2 1 4 4 4 2 CD47 immunoglobulin-like domain Izumo-Ig PF16706.3 078745.3_18529001_1 - 0.001 19.0 0.3 14 5.7 0.0 5.5 7 0 0 7 7 7 0 Izumo-like Immunoglobulin domain Sporozoite_P67 PF05642.9 078745.3_18529001_1 - 0.057 11.4 8.2 0.082 10.8 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CH PF00307.29 134973.2_18524001_2 - 4.9e-08 33.0 0.0 1.3e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.6 134973.2_18524001_2 - 0.0093 15.6 0.2 0.034 13.8 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain zf-CCCH PF00642.22 134973.2_18524001_2 - 0.033 14.0 0.5 0.097 12.5 0.5 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cation_ATPase_C PF00689.19 134985.4_18529001_2 - 1.2e-05 24.9 4.1 1.2e-05 24.9 4.1 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus PI-PLC-X PF00388.17 134985.4_18529001_2 - 0.016 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Lig_chan PF00060.24 135019.2_18527001_3 - 2.1e-45 154.1 0.3 5e-45 152.8 0.3 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 135019.2_18527001_3 - 2.5e-34 117.8 0.3 5.3e-34 116.7 0.3 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 135019.2_18527001_3 - 2.7e-19 69.4 0.0 6.8e-19 68.1 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.14 135019.2_18527001_3 - 0.00013 21.8 3.7 0.00076 19.3 0.1 2.8 2 0 0 2 2 2 1 Ion channel ANF_receptor PF01094.26 135019.2_18527001_3 - 0.00046 19.3 0.0 0.00077 18.5 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region ASXH PF13919.4 135019.2_18527001_3 - 0.062 13.2 0.3 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Asx homology domain PMP1_2 PF08114.9 135019.2_18527001_3 - 0.088 12.4 0.2 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 ATPase proteolipid family MFS_1 PF07690.14 135021.4_18525001_1 - 1.3e-30 106.4 43.9 2.8e-16 59.3 18.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 135021.4_18525001_1 - 2.5e-06 26.5 30.7 0.00042 19.2 30.8 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Reticulon PF02453.15 175969.3_18526001_1 - 7.3e-44 149.3 5.2 7.3e-44 149.3 5.2 2.2 2 0 0 2 2 2 1 Reticulon Ig_3 PF13927.4 001201772.2_18525001_1 - 5.5e-39 132.5 0.6 5.4e-16 58.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.14 001201772.2_18525001_1 - 6.5e-36 122.1 0.0 1.6e-12 47.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.23 001201772.2_18525001_1 - 2.4e-22 78.7 0.1 9.5e-10 38.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001201772.2_18525001_1 - 2.5e-19 69.3 0.1 1.1e-10 41.5 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001201772.2_18525001_1 - 1e-15 57.7 0.8 5.8e-07 29.5 0.0 4.9 4 1 0 4 4 4 3 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.13 001201772.2_18525001_1 - 0.0035 17.0 0.0 0.083 12.5 0.0 2.5 2 0 0 2 2 2 1 Adenovirus E3 region protein CR1 C2-set_2 PF08205.10 001201772.2_18525001_1 - 0.0056 16.6 0.1 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Cpn60_TCP1 PF00118.22 164654.2_18525001_3 - 2.5e-82 276.9 12.5 9e-82 275.1 12.5 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family F5_F8_type_C PF00754.23 164688.2_18529001_3 - 2.6e-20 72.7 0.1 1.7e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 F5/8 type C domain TMEM154 PF15102.4 164688.2_18529001_3 - 0.031 14.1 0.1 0.075 12.8 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF912 PF06024.10 164688.2_18529001_3 - 0.07 13.3 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ASC PF00858.22 135173.2_18524001_1 - 1e-64 218.9 7.2 1.1e-64 218.7 7.2 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Fibrinogen_C PF00147.16 135174.3_18523001_3 - 4.8e-55 186.6 7.0 6.6e-55 186.2 7.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ACOX PF01756.17 135183.5_18525001_2 - 3.1e-43 147.3 0.0 4.8e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.17 135183.5_18525001_2 - 8.9e-18 64.2 0.0 1.6e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.22 135183.5_18525001_2 - 1.7e-07 31.4 0.1 8.4e-07 29.2 0.1 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNF PF00209.16 164766.3_18526001_2 - 5.2e-48 163.9 34.8 7.3e-48 163.4 34.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CUB PF00431.18 164771.4_18525001_3 - 8.8e-12 45.2 0.1 1.7e-09 37.9 0.0 3.1 3 0 0 3 3 3 1 CUB domain Activator_LAG-3 PF11498.6 164771.4_18525001_3 - 9.2e-06 24.8 46.4 9.2e-06 24.8 46.4 1.6 2 0 0 2 2 2 1 Transcriptional activator LAG-3 TFIIA PF03153.11 164771.4_18525001_3 - 3 7.6 30.8 5.7 6.7 30.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1674 PF07896.10 135326.5_18522001_3 - 1e-19 70.6 4.0 2.1e-19 69.6 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Lipase PF00151.17 135331.2_18523001_1 - 1e-58 199.2 0.0 1.4e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.5 135331.2_18523001_1 - 0.00022 21.8 0.0 0.00038 21.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.16 135331.2_18523001_1 - 0.00023 20.6 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) DUF676 PF05057.12 135331.2_18523001_1 - 0.0029 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.7 135331.2_18523001_1 - 0.023 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.18 135331.2_18523001_1 - 0.029 13.9 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.11 135331.2_18523001_1 - 0.041 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.10 135331.2_18523001_1 - 0.044 13.1 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Metallophos PF00149.26 164798.3_18524001_1 - 4.6e-13 50.0 1.1 8.4e-13 49.2 1.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.5 164798.3_18524001_1 - 0.0081 16.3 1.0 0.044 13.9 1.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mss4 PF04421.11 135365.3_18522001_1 - 8.4e-31 105.9 0.1 1.2e-30 105.4 0.1 1.2 1 0 0 1 1 1 1 Mss4 protein HEAT PF02985.20 001032056.3_18525001_1 - 5.2e-45 147.4 33.3 9.8e-05 22.1 0.0 13.7 15 0 0 15 15 15 12 HEAT repeat HEAT_2 PF13646.4 001032056.3_18525001_1 - 5.4e-41 138.8 6.4 1.8e-12 47.3 0.0 7.1 2 2 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.5 001032056.3_18525001_1 - 9.3e-12 45.2 2.5 0.064 13.7 0.0 6.8 4 1 4 8 8 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.5 001032056.3_18525001_1 - 3.1e-09 36.9 8.7 0.011 15.6 0.1 4.8 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.4 001032056.3_18525001_1 - 1.4e-08 34.9 17.7 0.00012 22.3 0.1 8.4 6 3 3 9 9 9 1 HEAT-like repeat Adaptin_N PF01602.18 001032056.3_18525001_1 - 1.1e-07 30.7 3.2 0.00094 17.7 0.1 3.0 1 1 0 2 2 2 2 Adaptin N terminal region Ecm29 PF13001.5 001032056.3_18525001_1 - 1.2 7.5 7.5 0.69 8.4 0.1 3.6 4 1 1 5 5 5 0 Proteasome stabiliser LRR_4 PF12799.5 135390.4_18523001_3 - 0.0093 16.2 18.0 1.7 9.0 0.2 6.2 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) MIF4G PF02854.17 135475.3_18527001_1 - 1.8e-41 142.0 0.4 2.9e-41 141.3 0.4 1.3 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.13 135475.3_18527001_1 - 0.2 11.3 0.4 0.49 10.1 0.4 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region FAST_1 PF06743.13 135485.7_18529001_3 - 0.00012 21.8 3.8 0.014 15.1 0.1 3.9 3 1 1 4 4 4 2 FAST kinase-like protein, subdomain 1 ANAPC4_WD40 PF12894.5 135506.2_18523001_3 - 7.6e-05 22.8 0.2 0.2 11.9 0.0 3.7 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.30 135506.2_18523001_3 - 0.0098 16.6 0.1 0.0098 16.6 0.1 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Nrf1_DNA-bind PF10491.7 135516.3_18525001_1 - 6.5e-12 45.5 0.0 2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 JmjC PF02373.20 164907.4_18527001_3 - 7.7e-32 110.0 4.5 1.3e-31 109.2 2.0 2.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase TPR_1 PF00515.26 164907.4_18527001_3 - 1.4e-13 49.9 22.4 2.9e-06 26.7 0.0 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.4 164907.4_18527001_3 - 2.6e-12 46.1 2.0 0.014 15.6 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.15 164907.4_18527001_3 - 1.5e-06 27.7 20.4 0.51 10.5 0.5 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.4 164907.4_18527001_3 - 1.7e-06 27.6 17.0 0.55 10.5 0.0 7.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.4 164907.4_18527001_3 - 4e-06 26.9 7.3 0.0021 18.2 0.1 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.4 164907.4_18527001_3 - 1.5e-05 25.3 3.3 0.13 12.7 1.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.4 164907.4_18527001_3 - 0.00023 20.6 9.0 0.024 14.2 0.3 5.0 3 1 3 6 6 6 2 TPR repeat TPR_16 PF13432.4 164907.4_18527001_3 - 0.00042 20.8 0.1 0.89 10.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.4 164907.4_18527001_3 - 0.0027 18.3 0.4 11 7.1 0.0 4.4 2 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.5 164907.4_18527001_3 - 0.016 15.2 2.5 0.027 14.6 0.2 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.4 164907.4_18527001_3 - 0.018 15.0 0.3 0.28 11.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.4 164907.4_18527001_3 - 0.091 12.7 6.0 3.5 7.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.4 164907.4_18527001_3 - 0.096 13.2 3.1 91 3.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.4 164907.4_18527001_3 - 0.23 11.3 0.5 41 4.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydro_lipase PF04083.14 164937.3_18527001_1 - 3e-14 52.2 0.0 8.8e-14 50.7 0.0 1.9 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.18 164937.3_18527001_1 - 4.7e-13 49.2 0.0 4.7e-13 49.2 0.0 3.2 2 1 0 3 3 3 1 alpha/beta hydrolase fold RNA_pol_inhib PF16857.3 164937.3_18527001_1 - 0.019 14.6 3.2 2.4 7.9 0.3 3.3 2 0 0 2 2 2 0 RNA polymerase inhibitor VWC PF00093.16 164944.4_18528001_1 - 0.00093 19.3 13.6 0.00093 19.3 13.6 2.5 2 0 0 2 2 2 1 von Willebrand factor type C domain FXR_C1 PF16096.3 164944.4_18528001_1 - 0.016 15.3 0.7 0.057 13.5 0.7 1.9 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 CstA PF02554.12 164944.4_18528001_1 - 0.21 10.3 2.5 0.31 9.7 2.5 1.1 1 0 0 1 1 1 0 Carbon starvation protein CstA Ge1_WD40 PF16529.3 164957.2_18529001_3 - 3.4e-150 499.4 1.2 3.4e-150 499.4 1.2 1.7 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.30 164957.2_18529001_3 - 0.0012 19.5 0.2 0.12 13.1 0.0 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 164957.2_18529001_3 - 0.0015 18.7 0.0 0.0096 16.1 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3226 PF11536.6 164957.2_18529001_3 - 0.049 13.2 1.4 0.11 12.1 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) RskA PF10099.7 164957.2_18529001_3 - 0.29 11.3 11.0 0.18 11.9 7.5 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA YpjP PF14005.4 164957.2_18529001_3 - 3.8 7.4 5.3 0.77 9.7 0.4 2.4 2 0 0 2 2 2 0 YpjP-like protein DNA_methylase PF00145.15 058127.4_18523001_1 - 8.5e-44 150.1 0.0 1.2e-43 149.6 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase MTS PF05175.12 058127.4_18523001_1 - 0.048 13.1 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PfkB PF00294.22 135716.3_18523001_1 - 4.2e-53 180.5 0.8 5e-53 180.2 0.8 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.10 135716.3_18523001_1 - 0.00033 20.0 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF4755 PF15947.3 135716.3_18523001_1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4755) OATP PF03137.18 135726.3_18526001_2 - 2e-72 244.1 22.4 2.3e-71 240.6 22.4 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.14 135726.3_18526001_2 - 4.8e-11 42.0 25.0 4.8e-11 42.0 25.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.13 135726.3_18526001_2 - 0.0016 18.5 4.2 0.003 17.6 4.2 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain TSC22 PF01166.16 165012.2_18525001_1 - 1.1e-25 89.6 6.8 2.1e-25 88.7 6.8 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.11 165012.2_18525001_1 - 4.5 7.8 8.0 0.18 12.3 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF1771 PF08590.8 165035.4_18527001_2 - 0.093 13.0 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Fra10Ac1 PF09725.7 165057.4_18523001_3 - 1.4e-49 167.1 0.9 2.6e-49 166.3 0.9 1.4 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Vpu PF00558.17 165057.4_18523001_3 - 6.2 6.5 7.5 17 5.1 7.5 1.7 1 0 0 1 1 1 0 Vpu protein Ig_3 PF13927.4 001014485.5_18529001_1 - 2.6e-46 156.0 4.4 1.2e-09 38.6 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.14 001014485.5_18529001_1 - 6.4e-34 115.8 0.1 1.6e-08 34.4 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.4 001014485.5_18529001_1 - 4.3e-31 107.0 2.3 4.8e-09 36.3 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.23 001014485.5_18529001_1 - 2e-23 82.2 16.5 4.7e-06 26.5 0.0 6.4 6 1 0 6 6 6 5 Immunoglobulin domain C2-set_2 PF08205.10 001014485.5_18529001_1 - 2e-17 62.9 1.2 8.5e-10 38.5 0.0 3.7 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.15 001014485.5_18529001_1 - 6.9e-10 38.9 0.3 2.5e-05 24.2 0.0 4.9 5 0 0 5 5 5 2 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001014485.5_18529001_1 - 0.0034 17.3 0.0 2.5 8.1 0.0 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain CDV3 PF15359.4 135934.2_18522001_2 - 2.1e-12 47.5 6.4 2.1e-12 47.5 6.4 1.8 2 1 0 2 2 2 1 Carnitine deficiency-associated protein 3 MNNL PF07657.11 135964.3_18524001_2 - 0.93 9.4 9.9 0.048 13.6 3.8 2.0 1 1 1 2 2 2 0 N terminus of Notch ligand zf-FCS PF06467.12 135964.3_18524001_3 - 0.13 12.2 6.9 0.5 10.3 1.7 2.4 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.24 135964.3_18524001_3 - 1.3 9.5 7.8 9.3 6.8 0.2 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 135964.3_18524001_3 - 6.4 7.8 14.3 3.4 8.6 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger FSA_C PF10479.7 001201896.2_18529001_1 - 0 1362.8 2.6 0 1362.1 2.6 1.4 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus DUF1127 PF06568.9 135995.4_18523001_2 - 0.046 13.3 0.4 0.14 11.7 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) DivIC PF04977.13 135995.4_18523001_2 - 0.048 13.3 22.1 0.43 10.3 4.8 4.3 4 0 0 4 4 4 0 Septum formation initiator ATG16 PF08614.9 135995.4_18523001_2 - 0.1 12.6 29.7 1.1 9.3 17.2 3.2 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.10 135995.4_18523001_2 - 0.21 10.8 5.5 2.8 7.1 3.1 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Syntaxin_2 PF14523.4 135995.4_18523001_2 - 0.73 10.1 22.3 0.34 11.2 0.3 3.3 2 1 1 3 3 3 0 Syntaxin-like protein DUF948 PF06103.9 135995.4_18523001_2 - 1.1 9.5 12.2 5.4 7.2 0.4 4.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.11 135995.4_18523001_2 - 2.4 7.8 15.8 8.4 6.0 7.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Laminin_II PF06009.10 135995.4_18523001_2 - 2.8 7.8 17.2 0.15 12.0 4.1 3.0 1 1 2 3 3 3 0 Laminin Domain II FlaC_arch PF05377.9 135995.4_18523001_2 - 4.4 7.6 14.6 1.5 9.1 1.4 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) IncA PF04156.12 135995.4_18523001_2 - 5.7 6.6 35.9 0.66 9.6 14.0 2.1 2 0 0 2 2 2 0 IncA protein Rop-like PF05082.11 135995.4_18523001_2 - 6.1 6.6 8.4 9.1 6.1 1.1 3.3 3 0 0 3 3 3 0 Rop-like CD36 PF01130.19 165238.3_18525001_1 - 3.8e-121 404.7 0.0 4.8e-121 404.4 0.0 1.0 1 0 0 1 1 1 1 CD36 family zf-C2H2_6 PF13912.4 136080.3_18527001_2 - 2.8e-07 30.2 0.2 2.8e-07 30.2 0.2 7.6 7 0 0 7 7 7 3 C2H2-type zinc finger zf-AD PF07776.13 136080.3_18527001_2 - 3.2e-06 27.2 8.1 3.2e-06 27.2 8.1 3.5 4 0 0 4 4 4 1 Zinc-finger associated domain (zf-AD) zf-C2H2 PF00096.24 136080.3_18527001_2 - 2.8e-05 24.2 66.1 0.0028 17.9 1.2 9.1 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-met PF12874.5 136080.3_18527001_2 - 7.4e-05 22.9 27.4 0.021 15.0 0.1 6.7 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.4 136080.3_18527001_2 - 0.002 18.7 5.8 0.0096 16.5 0.9 10.1 9 0 0 9 9 9 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 136080.3_18527001_2 - 0.0048 17.2 1.7 0.0048 17.2 1.7 8.7 9 1 0 9 9 9 3 Zinc-finger double domain zf-C2H2_jaz PF12171.6 136080.3_18527001_2 - 0.023 14.9 0.3 0.023 14.9 0.3 7.0 7 1 1 8 8 8 0 Zinc-finger double-stranded RNA-binding Pkinase_Tyr PF07714.15 057993.4_18526001_2 - 4.8e-67 225.8 0.0 1e-66 224.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase WIF PF02019.16 057993.4_18526001_2 - 7.1e-42 142.1 0.0 1.1e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 WIF domain Pkinase PF00069.23 057993.4_18526001_2 - 1.2e-25 90.3 0.0 3.4e-25 88.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.4 057993.4_18526001_2 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like LIM PF00412.20 165295.2_18525001_3 - 5.5e-62 205.7 44.0 7.8e-17 61.1 1.3 4.3 4 0 0 4 4 4 4 LIM domain LIM PF00412.20 165294.3_18525001_2 - 1.2e-61 204.6 44.0 9.8e-17 60.8 1.3 4.4 4 0 0 4 4 4 4 LIM domain zf-dskA_traR PF01258.15 165294.3_18525001_2 - 2.2 8.1 15.3 0.25 11.2 0.4 3.9 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger LIM PF00412.20 001038824.2_18526001_3 - 1.7e-61 204.2 44.0 1e-16 60.7 1.3 4.3 4 0 0 4 4 4 4 LIM domain zf-dskA_traR PF01258.15 001038824.2_18526001_3 - 3 7.7 15.3 0.27 11.1 0.4 3.8 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Prok-RING_4 PF14447.4 176061.3_18524001_3 - 0.0017 18.1 10.4 0.0033 17.1 10.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 176061.3_18524001_3 - 0.029 14.2 12.1 0.06 13.2 12.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FoP_duplication PF13865.4 176061.3_18524001_3 - 0.043 14.3 8.4 0.12 12.8 8.4 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-C3HC4_2 PF13923.4 176061.3_18524001_3 - 0.3 10.8 13.4 0.75 9.6 13.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 176061.3_18524001_3 - 0.39 10.6 8.7 0.77 9.7 8.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.23 176061.3_18524001_3 - 0.6 9.9 13.2 1.5 8.7 13.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 176061.3_18524001_3 - 3.9 7.7 13.8 7.9 6.7 13.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C2H2 PF00096.24 136152.4_18527001_1 - 4.8e-17 61.3 65.6 0.00021 21.5 3.9 8.9 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 136152.4_18527001_1 - 6.8e-15 54.6 57.9 1.4e-06 28.4 0.3 9.0 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_4 PF13894.4 136152.4_18527001_1 - 5.5e-14 51.5 68.2 0.0052 17.4 2.5 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_6 PF13912.4 136152.4_18527001_1 - 3.6e-06 26.7 47.2 0.00031 20.5 0.3 7.6 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 136152.4_18527001_1 - 3e-05 24.1 38.2 0.089 13.0 1.0 7.8 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 136152.4_18527001_1 - 8.4e-05 22.7 54.0 0.21 11.9 0.8 8.0 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-Di19 PF05605.10 136152.4_18527001_1 - 0.0066 16.6 29.0 0.039 14.1 0.6 5.2 5 0 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding AAA_22 PF13401.4 136167.3_18529001_2 - 5.6e-07 29.8 0.0 4e-06 27.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.27 136167.3_18529001_2 - 7.9e-06 26.2 0.0 3.2e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 136167.3_18529001_2 - 0.00077 19.7 0.1 0.065 13.5 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.15 136167.3_18529001_2 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.4 136167.3_18529001_2 - 0.0015 18.5 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.12 136167.3_18529001_2 - 0.0018 18.2 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.4 136167.3_18529001_2 - 0.0048 16.9 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.19 136167.3_18529001_2 - 0.0074 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF935 PF06074.10 136167.3_18529001_2 - 0.0077 14.9 1.8 0.013 14.1 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF935) PhoH PF02562.14 136167.3_18529001_2 - 0.023 14.0 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.4 136167.3_18529001_2 - 0.026 14.9 0.1 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.20 136167.3_18529001_2 - 0.05 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.4 136167.3_18529001_2 - 0.059 12.8 0.2 0.66 9.4 0.0 2.6 2 1 0 3 3 3 0 AAA domain NACHT PF05729.10 136167.3_18529001_2 - 0.097 12.5 0.3 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.4 136167.3_18529001_2 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IncA PF04156.12 136167.3_18529001_2 - 0.67 9.6 3.6 7 6.3 0.8 2.4 2 0 0 2 2 2 0 IncA protein COG5 PF10392.7 136167.3_18529001_2 - 1.3 9.0 6.6 7.8 6.6 1.9 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 SKA1 PF07160.10 136167.3_18529001_2 - 2 8.0 6.4 4.7 6.8 0.9 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF972 PF06156.11 136167.3_18529001_2 - 2.9 8.4 5.8 4.4 7.8 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.6 136167.3_18529001_2 - 3.4 7.8 10.8 4.4 7.4 4.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.6 136167.3_18529001_2 - 4.5 7.3 11.4 7.3 6.6 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Ceramidase PF05875.10 136176.4_18525001_2 - 1.2e-56 191.9 10.7 1.9e-56 191.3 10.7 1.3 1 0 0 1 1 1 1 Ceramidase LRR_4 PF12799.5 136207.4_18525001_3 - 4.3e-08 33.2 7.5 0.14 12.5 1.5 5.2 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.31 136207.4_18525001_3 - 0.00076 19.2 0.1 0.0029 17.3 0.1 2.1 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.31 136207.4_18525001_3 - 0.021 15.1 9.7 10 6.9 0.2 5.6 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.4 136207.4_18525001_3 - 0.63 9.7 12.0 0.17 11.6 1.8 3.9 4 2 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.4 136207.4_18525001_3 - 4.9 7.3 15.5 58 4.0 0.7 6.2 6 0 0 6 6 6 0 Leucine Rich repeat EcKinase PF02958.18 001014493.3_18524001_1 - 4.4e-36 124.6 1.1 6.9e-36 123.9 1.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.9 001014493.3_18524001_1 - 1e-18 67.3 0.8 1.5e-18 66.7 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.21 001014493.3_18524001_1 - 2.8e-08 33.9 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.18 001014493.3_18524001_1 - 0.0071 15.8 0.1 0.027 13.9 0.0 2.0 2 1 0 2 2 2 1 Choline/ethanolamine kinase Albumin_I PF08027.9 165402.3_18525001_1 - 0.044 13.6 0.7 0.13 12.1 0.7 1.7 1 0 0 1 1 1 0 Albumin I chain b CitMHS PF03600.14 165402.3_18525001_2 - 6.8e-47 160.0 29.1 6.9e-47 160.0 27.6 1.8 2 0 0 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.17 165402.3_18525001_2 - 8.7e-05 21.6 15.1 8.7e-05 21.6 15.1 2.9 3 0 0 3 3 3 1 Sodium:sulfate symporter transmembrane region G-patch PF01585.21 001042959.3_18523001_3 - 8.8e-12 44.6 0.5 2e-11 43.5 0.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.20 001042959.3_18523001_3 - 9.2e-05 22.1 0.1 0.00018 21.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.21 001042960.3_18523001_1 - 1e-11 44.4 0.5 2.2e-11 43.3 0.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.20 001042960.3_18523001_1 - 0.0001 21.9 0.1 0.0002 21.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cys_knot PF00007.20 001015386.3_18522001_2 - 3.1e-06 27.3 9.4 6.9e-06 26.2 9.4 1.5 1 0 0 1 1 1 1 Cystine-knot domain SH3_9 PF14604.4 001273734.1_18529001_1 - 5.1e-60 199.0 2.2 7.8e-17 60.7 0.2 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.26 001273734.1_18529001_1 - 3.6e-50 167.2 3.8 3.8e-15 55.1 0.1 4.4 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.15 001273734.1_18529001_1 - 7.7e-43 143.9 0.1 1.7e-10 40.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain EF-hand_4 PF12763.5 001273734.1_18529001_1 - 7.5e-31 106.0 0.0 9.1e-15 54.4 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.30 001273734.1_18529001_1 - 7.9e-09 34.3 0.1 0.0067 15.8 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.4 001273734.1_18529001_1 - 8.4e-05 22.1 0.1 6.9 6.8 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.4 001273734.1_18529001_1 - 0.00044 20.5 0.0 0.43 11.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001273734.1_18529001_1 - 0.094 12.4 2.1 0.2 11.3 0.2 2.2 2 0 0 2 2 2 0 EF-hand domain pair Reo_sigmaC PF04582.10 001273734.1_18529001_1 - 0.19 10.9 12.8 0.32 10.2 3.1 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein FH2 PF02181.21 165341.3_18529001_1 - 9.4e-108 360.5 11.1 9.4e-108 360.5 11.1 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.14 165341.3_18529001_1 - 3.2e-57 193.2 1.2 3.2e-57 193.2 1.2 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.11 165341.3_18529001_1 - 8.3e-53 178.6 1.0 8.3e-53 178.6 1.0 2.9 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Drf_DAD PF06345.9 165341.3_18529001_1 - 9.4e-08 31.4 1.1 2.2e-07 30.3 1.1 1.7 1 0 0 1 1 1 1 DRF Autoregulatory Domain DUF2207 PF09972.7 165341.3_18529001_1 - 0.11 11.1 0.8 0.23 10.1 0.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) IBN_N PF03810.17 001259180.2_18528001_3 - 1.4e-16 60.0 3.2 1.1e-15 57.2 0.7 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.4 001259180.2_18528001_3 - 1.8e-15 56.9 1.0 1.6e-08 34.7 0.0 7.3 9 0 0 9 9 9 2 HEAT-like repeat HEAT PF02985.20 001259180.2_18528001_3 - 1e-14 53.2 3.7 0.0065 16.5 0.0 8.8 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.4 001259180.2_18528001_3 - 1e-06 28.9 0.2 0.093 13.0 0.0 5.0 5 1 1 6 6 6 3 HEAT repeats Arm PF00514.21 001259180.2_18528001_3 - 0.0038 17.1 0.0 0.44 10.5 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat 3-PAP PF12578.6 001259180.2_18528001_3 - 0.032 13.8 0.1 0.078 12.6 0.1 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein CLASP_N PF12348.6 001259180.2_18528001_3 - 0.04 13.4 7.2 1.4 8.3 0.1 3.7 5 0 0 5 5 5 0 CLASP N terminal DUF3708 PF12501.6 001259180.2_18528001_3 - 0.098 12.3 0.2 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter ParcG PF10274.7 001259180.2_18528001_3 - 0.15 12.0 5.2 2.8 7.9 0.1 3.4 4 0 0 4 4 4 0 Parkin co-regulated protein S-AdoMet_synt_C PF02773.14 164361.2_18525001_2 - 4.6e-67 224.1 0.0 7.6e-67 223.4 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.14 164361.2_18525001_2 - 1.8e-42 144.2 0.0 2.9e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.18 164361.2_18525001_3 - 5.7e-43 145.5 0.1 8.4e-43 145.0 0.1 1.2 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_N PF00438.18 001258885.2_18522001_3 - 1.8e-36 124.6 0.2 2.6e-36 124.1 0.2 1.2 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.17 001258885.2_18522001_3 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Gln-synt_C PF00120.22 057222.4_18525001_1 - 6.9e-19 67.9 0.0 3.2e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 057222.4_18525001_1 - 6.1e-09 35.3 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Ion_trans PF00520.29 001144310.1_18525001_1 - 5.1e-44 150.2 15.7 7e-44 149.8 15.7 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001144310.1_18525001_1 - 9.4e-29 99.5 0.0 2e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001144310.1_18525001_1 - 2.8e-10 39.9 4.4 2.8e-10 39.9 4.4 2.2 3 0 0 3 3 3 1 Ion channel Forkhead PF00250.16 057486.4_18525001_2 - 8.3e-38 128.5 0.2 1.6e-37 127.6 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain Collagen PF01391.16 057486.4_18525001_2 - 0.5 10.0 13.3 0.9 9.2 13.3 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) PPTA PF01239.20 001273119.1_18523001_3 - 6.5e-46 152.7 11.9 5.2e-10 38.6 0.2 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RINGv PF12906.5 134881.6_18526001_3 - 5.9e-13 48.6 11.8 5.9e-13 48.6 11.8 2.0 2 0 0 2 2 2 1 RING-variant domain DUF1084 PF06454.9 134881.6_18526001_3 - 8.7e-07 28.5 11.4 2.1e-06 27.2 11.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) EGF_2 PF07974.11 134881.6_18526001_3 - 0.0002 21.5 6.3 0.00062 20.0 6.3 1.9 1 0 0 1 1 1 1 EGF-like domain zf-RING_2 PF13639.4 134881.6_18526001_3 - 0.2 11.8 10.3 0.78 9.9 10.3 2.2 1 0 0 1 1 1 0 Ring finger domain GDA1_CD39 PF01150.15 164513.4_18525001_1 - 4e-73 246.4 0.0 4.7e-72 242.9 0.0 1.9 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.14 164513.4_18525001_1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family PsbI PF02532.12 164513.4_18525001_1 - 0.68 9.8 2.9 1.5 8.7 2.9 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) AhpC-TSA PF00578.19 078739.3_18522001_3 - 8.6e-31 106.3 0.0 1.2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 078739.3_18522001_3 - 3.5e-12 46.1 0.0 4.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 078739.3_18522001_3 - 1.4e-09 37.5 0.3 2.3e-09 36.8 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.4 078739.3_18522001_3 - 0.0025 17.8 0.0 0.0052 16.8 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme RNase_H_2 PF13482.4 001298642.1_18523001_1 - 0.0012 18.7 0.0 0.0048 16.8 0.0 2.0 2 1 0 2 2 2 1 RNase_H superfamily RNase_T PF00929.22 001298642.1_18523001_1 - 0.0081 16.6 0.0 0.12 12.8 0.0 2.5 2 1 0 2 2 2 1 Exonuclease DNA_pol_B_exo1 PF03104.17 001298642.1_18523001_1 - 0.047 12.7 0.0 0.079 12.0 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase family B, exonuclease domain zf-C2H2 PF00096.24 057534.4_18526001_3 - 8.1e-22 76.3 40.5 1.8e-05 24.8 3.3 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 057534.4_18526001_3 - 2.6e-19 68.6 34.8 4.2e-05 23.7 0.1 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 057534.4_18526001_3 - 5.3e-16 57.8 36.1 0.0011 19.5 2.3 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.4 057534.4_18526001_3 - 7.1e-11 41.7 25.2 0.0004 20.1 0.5 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 057534.4_18526001_3 - 1.1e-05 25.4 24.6 0.012 15.7 2.5 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding C1_4 PF07975.10 057534.4_18526001_3 - 2e-05 24.6 14.6 0.11 12.6 1.6 4.0 3 0 0 3 3 3 3 TFIIH C1-like domain zf-met PF12874.5 057534.4_18526001_3 - 6.2e-05 23.1 32.3 0.0011 19.1 1.8 5.4 6 0 0 6 6 5 3 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.8 057534.4_18526001_3 - 0.0029 17.6 17.5 0.3 11.1 1.1 3.8 3 0 0 3 3 3 2 Zinc ribbon domain Rad50_zn_hook PF04423.12 057534.4_18526001_3 - 0.003 17.2 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 Rad50 zinc hook motif GAGA PF09237.9 057534.4_18526001_3 - 0.027 14.1 13.6 0.52 10.0 0.6 4.2 1 1 3 4 4 4 0 GAGA factor zf-C2H2_9 PF16293.3 057534.4_18526001_3 - 0.13 12.0 0.9 0.9 9.3 0.2 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.4 057534.4_18526001_3 - 1.2 9.0 21.2 0.13 12.0 1.5 4.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type FYVE PF01363.19 057534.4_18526001_3 - 1.3 9.1 24.5 0.52 10.4 4.7 3.9 1 1 1 2 2 2 0 FYVE zinc finger Pex19 PF04614.10 057534.4_18526001_3 - 5 6.7 5.5 3.3 7.3 3.0 1.8 1 1 0 1 1 1 0 Pex19 protein family FH2 PF02181.21 001144311.2_18529001_3 - 8e-74 248.8 1.6 1.4e-73 248.1 0.3 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain WD40 PF00400.30 134657.3_18523001_3 - 6.2e-56 185.0 5.6 2.2e-08 34.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 134657.3_18523001_3 - 5.8e-14 52.0 0.0 0.049 13.8 0.0 5.6 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 134657.3_18523001_3 - 2.7e-12 46.9 0.0 0.00073 19.3 0.0 3.2 2 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 134657.3_18523001_3 - 1.5e-07 30.6 0.0 0.022 13.6 0.0 3.5 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.6 134657.3_18523001_3 - 1.1e-05 24.1 0.2 0.73 8.2 0.0 3.9 4 1 0 4 4 4 3 Nucleoporin Nup120/160 zf-AD PF07776.13 001258882.2_18527001_2 - 4.2e-07 30.0 0.8 1.4e-06 28.3 0.4 2.1 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) GGDEF PF00990.19 001258882.2_18527001_2 - 0.0063 16.2 0.5 0.033 13.8 0.0 2.5 3 0 0 3 3 3 1 Diguanylate cyclase, GGDEF domain DUF1604 PF07713.11 001258882.2_18527001_2 - 0.023 14.4 0.3 0.068 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Gal-bind_lectin PF00337.20 001258884.1_18523001_1 - 5.7e-72 239.4 0.0 2.6e-38 130.5 0.0 2.6 2 1 1 3 3 3 2 Galactoside-binding lectin NADH_dehy_S2_C PF06444.9 001258887.2_18529001_1 - 1 9.8 4.6 5 7.6 0.3 3.4 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus SPOC PF07744.11 001258887.2_18529001_3 - 2.5e-34 118.2 0.1 2.5e-34 118.2 0.1 2.1 2 0 0 2 2 2 1 SPOC domain RRM_1 PF00076.20 001258887.2_18529001_3 - 2.6e-24 84.7 0.9 1e-11 44.3 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001258887.2_18529001_3 - 0.042 13.7 0.1 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.20 001258902.2_18528001_1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.7 001258902.2_18528001_1 - 6.6 5.2 20.3 12 4.3 20.3 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 G-patch PF01585.21 001258902.2_18528001_2 - 3.4e-17 61.9 3.9 6.5e-17 61.0 3.9 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.5 001258902.2_18528001_2 - 2.6e-08 33.7 0.7 7.1e-08 32.3 0.7 1.7 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.16 001258902.2_18528001_2 - 2.4e-05 23.4 2.3 5.3e-05 22.3 2.3 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C2H2_2 PF12756.5 001258902.2_18528001_2 - 0.019 15.2 2.2 0.8 9.9 0.1 2.9 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.14 001258902.2_18528001_2 - 0.089 13.0 1.0 0.19 11.9 1.0 1.5 1 0 0 1 1 1 0 C1 domain PEARLI-4 PF05278.10 001258902.2_18528001_2 - 0.17 11.3 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Dynein_light PF01221.16 001258907.2_18522001_2 - 1.3e-42 143.9 1.3 1.8e-42 143.4 1.3 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 zf-C2H2 PF00096.24 001258933.2_18527001_2 - 3.4e-22 77.5 41.2 4.4e-05 23.6 3.4 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001258933.2_18527001_2 - 3.7e-19 68.1 39.0 4.5e-05 23.6 2.4 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 001258933.2_18527001_2 - 4.4e-17 61.2 36.5 0.0016 19.0 1.6 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001258933.2_18527001_2 - 4.5e-11 42.3 27.1 0.00054 19.7 0.5 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger C1_4 PF07975.10 001258933.2_18527001_2 - 0.0011 19.1 15.6 0.32 11.2 2.3 3.5 3 0 0 3 3 3 2 TFIIH C1-like domain zf-C2H2_jaz PF12171.6 001258933.2_18527001_2 - 0.0015 18.7 32.7 0.017 15.3 2.5 6.5 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.12 001258933.2_18527001_2 - 0.0017 18.0 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Rad50 zinc hook motif Zn-ribbon_8 PF09723.8 001258933.2_18527001_2 - 0.0035 17.3 18.3 0.43 10.6 1.2 3.7 3 0 0 3 3 3 3 Zinc ribbon domain zf-met PF12874.5 001258933.2_18527001_2 - 0.011 15.9 36.3 0.024 14.9 1.8 5.7 7 0 0 7 7 6 0 Zinc-finger of C2H2 type GAGA PF09237.9 001258933.2_18527001_2 - 0.1 12.3 13.1 0.66 9.7 0.6 3.9 1 1 3 4 4 4 0 GAGA factor NADH-G_4Fe-4S_3 PF10588.7 001258933.2_18527001_2 - 1.2 8.5 4.9 6.7 6.2 0.3 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region PHD_4 PF16866.3 001258933.2_18527001_2 - 2.2 8.3 7.9 4.7 7.2 0.9 2.6 2 0 0 2 2 2 0 PHD-finger FYVE PF01363.19 001258933.2_18527001_2 - 8.3 6.5 24.7 0.66 10.0 4.7 3.2 1 1 1 2 2 2 0 FYVE zinc finger Ribosomal_L39 PF00832.18 001258974.1_18525001_1 - 0.087 12.3 1.8 0.16 11.5 0.1 2.3 2 0 0 2 2 2 0 Ribosomal L39 protein Propep_M14 PF02244.14 001259002.1_18522001_3 - 2.2e-12 47.0 1.1 3.4e-12 46.4 1.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase activation peptide SET PF00856.26 001259033.2_18524001_1 - 7.6e-05 23.0 0.0 0.00017 21.9 0.0 1.6 1 1 0 1 1 1 1 SET domain Ras PF00071.20 164476.2_18524001_2 - 1.4e-60 203.5 0.3 2e-60 203.0 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 164476.2_18524001_2 - 5.5e-35 120.1 0.1 1.2e-34 119.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 164476.2_18524001_2 - 6.6e-12 45.1 0.1 9.8e-12 44.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 164476.2_18524001_2 - 0.00016 21.0 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 164476.2_18524001_2 - 0.00018 21.4 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 164476.2_18524001_2 - 0.0026 17.5 0.2 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.4 164476.2_18524001_2 - 0.16 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PDEase_I PF00233.17 001259065.2_18529001_1 - 1.6e-81 273.4 2.6 2.8e-81 272.6 2.6 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.10 001259065.2_18529001_1 - 1.3e-32 111.2 0.2 2.8e-32 110.2 0.2 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal PRMT5 PF05185.14 001298671.1_18524001_2 - 3.9e-08 32.7 0.1 7.6e-08 31.7 0.0 1.5 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.11 001298671.1_18524001_2 - 4.7e-08 32.6 0.0 7.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.4 001298671.1_18524001_2 - 1.1e-07 32.3 0.1 2.7e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 001298671.1_18524001_2 - 1.7e-06 28.4 0.1 5.5e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.4 001298671.1_18524001_2 - 1.9e-06 27.7 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.12 001298671.1_18524001_2 - 1.4e-05 24.6 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.17 001298671.1_18524001_2 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.4 001298671.1_18524001_2 - 0.0037 17.1 0.0 0.012 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001298671.1_18524001_2 - 0.0063 17.1 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.18 001298671.1_18524001_2 - 0.0088 15.2 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.4 001298671.1_18524001_2 - 0.013 16.4 0.0 0.032 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.5 001298671.1_18524001_2 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CLPTM1 PF05602.10 001273088.1_18525001_3 - 2.3e-149 498.0 2.1 2.8e-149 497.7 2.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.12 001273088.1_18525001_3 - 0.068 12.8 6.3 0.92 9.2 0.1 3.1 3 0 0 3 3 3 0 PQ loop repeat DUF1097 PF06496.9 001273088.1_18525001_3 - 0.15 12.1 3.4 0.1 12.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) LEM PF03020.13 135437.4_18524001_2 - 0.0003 20.2 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 LEM domain VPS13 PF16908.3 135437.4_18524001_2 - 0.017 14.9 0.7 0.017 14.9 0.7 1.6 2 0 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal zf-C2H2 PF00096.24 057252.4_18525001_1 - 1.1e-24 85.4 35.9 3.8e-05 23.8 0.8 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 057252.4_18525001_1 - 4.3e-16 58.1 34.2 0.006 17.2 3.3 6.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 057252.4_18525001_1 - 5.1e-15 55.0 35.7 4.5e-06 26.7 1.4 6.6 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_jaz PF12171.6 057252.4_18525001_1 - 1.6e-09 37.7 17.0 0.0077 16.4 0.5 5.6 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 057252.4_18525001_1 - 3.9e-06 26.9 24.3 0.1 12.9 0.3 5.9 5 0 0 5 5 5 3 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.8 057252.4_18525001_1 - 0.004 17.1 17.4 0.89 9.6 0.1 4.5 2 1 2 4 4 4 2 Zinc ribbon domain zf-CHY PF05495.10 057252.4_18525001_1 - 0.025 15.0 3.1 0.025 15.0 3.1 3.1 3 0 0 3 3 2 0 CHY zinc finger zf-C2H2_6 PF13912.4 057252.4_18525001_1 - 0.053 13.3 0.4 0.053 13.3 0.4 5.9 6 0 0 6 6 5 0 C2H2-type zinc finger zf-C2HE PF16278.3 057252.4_18525001_1 - 0.07 13.5 27.0 0.63 10.4 1.6 5.4 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.9 057252.4_18525001_1 - 0.6 9.9 18.6 1.1 9.1 0.4 5.2 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zinc_ribbon_15 PF17032.3 057252.4_18525001_1 - 1.4 9.6 18.7 0.19 12.4 1.4 3.1 3 0 0 3 3 3 0 zinc-ribbon family DUF2180 PF09947.7 057252.4_18525001_1 - 5.7 6.9 7.8 7.6 6.5 1.3 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) ADK_lid PF05191.12 057252.4_18525001_1 - 9.8 6.2 11.1 1.7 8.6 1.4 3.6 3 1 1 4 4 4 0 Adenylate kinase, active site lid adh_short PF00106.23 078798.4_18522001_1 - 4.2e-35 120.8 8.1 6e-35 120.3 8.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 078798.4_18522001_1 - 4.7e-17 62.2 2.7 7.4e-17 61.6 2.7 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 078798.4_18522001_1 - 0.00015 21.6 1.3 0.00027 20.8 1.3 1.4 1 0 0 1 1 1 1 KR domain CRAL_TRIO PF00650.18 001259162.2_18524001_3 - 1.3e-39 135.4 0.1 2e-39 134.7 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.4 001259162.2_18524001_3 - 0.00017 21.5 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TAF PF02969.15 001272914.1_18525001_3 - 0.067 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) RAP1 PF07218.9 001272914.1_18525001_3 - 6.9 4.7 9.9 12 3.9 9.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC27 PF09507.8 135899.3_18523001_3 - 8.1e-05 22.1 72.3 0.00035 20.0 72.3 2.3 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Ribosomal_60s PF00428.17 057282.4_18522001_1 - 2.9e-28 98.1 6.4 3.6e-28 97.8 6.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.9 057282.4_18522001_1 - 0.1 10.9 0.1 0.13 10.6 0.1 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3824 PF12868.5 057282.4_18522001_1 - 0.18 12.3 2.7 0.32 11.5 2.7 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Collagen PF01391.16 164615.2_18529001_2 - 2.4e-205 664.4 745.7 2.3e-09 36.7 17.8 29.3 4 4 22 26 26 26 25 Collagen triple helix repeat (20 copies) C4 PF01413.17 164615.2_18529001_2 - 6.7e-77 254.9 4.1 7.2e-41 138.9 0.6 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen HABP4_PAI-RBP1 PF04774.13 165100.2_18527001_3 - 2.8e-25 89.3 11.1 2.8e-25 89.3 11.1 4.2 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.3 165100.2_18527001_3 - 0.0017 18.8 22.9 0.0017 18.8 22.9 4.0 3 1 1 4 4 4 1 Intracellular hyaluronan-binding protein 4 N-terminal MRJP PF03022.14 001299018.1_18524001_3 - 1.3e-110 369.1 0.0 1.7e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein Med15 PF09606.8 134684.3_18526001_2 - 8.9e-299 993.5 110.1 1.8e-231 771.0 60.7 2.0 1 1 1 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal KIX_2 PF16987.3 134684.3_18526001_2 - 0.0075 16.1 1.1 0.0075 16.1 1.1 2.5 2 0 0 2 2 2 1 KIX domain zf-C2H2 PF00096.24 205990.2_18527001_1 - 0.0003 20.9 0.1 0.0016 18.6 0.1 2.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 205990.2_18527001_1 - 0.055 13.3 0.2 0.055 13.3 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.4 205990.2_18527001_1 - 0.059 14.1 0.1 0.059 14.1 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Aminotran_1_2 PF00155.19 164445.4_18524001_2 - 4.5e-89 299.0 0.0 5.2e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HECT PF00632.23 001272966.1_18528001_2 - 3.9e-75 253.0 0.7 1.1e-73 248.3 0.1 2.4 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.17 001272966.1_18528001_2 - 1.4e-06 28.9 0.0 3.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Filamin/ABP280 repeat SAM_2 PF07647.15 001272966.1_18528001_2 - 0.0005 20.0 0.0 0.0046 16.9 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001272966.1_18528001_2 - 0.0038 17.5 0.0 0.18 12.1 0.0 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) CD36 PF01130.19 001272896.1_18526001_1 - 4.4e-143 477.0 0.4 5.8e-143 476.6 0.4 1.1 1 0 0 1 1 1 1 CD36 family 3HCDH_N PF02737.16 135455.3_18526001_3 - 5.1e-58 195.8 1.7 9.5e-58 194.9 1.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.18 135455.3_18526001_3 - 4.9e-35 120.9 0.1 7.8e-35 120.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.20 135455.3_18526001_3 - 3.2e-31 107.6 0.0 6.7e-25 87.4 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.3 135455.3_18526001_3 - 4e-23 82.3 0.0 7.3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.13 135455.3_18526001_3 - 0.016 15.2 2.4 0.026 14.6 1.1 2.0 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDI PF00996.16 001298852.1_18526001_1 - 2.3e-236 784.2 0.0 2.7e-236 783.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Glyco_hydro_18 PF00704.26 057910.5_18523001_1 - 9.5e-57 192.9 0.0 1.1e-56 192.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1707 PF08044.9 057910.5_18523001_1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) VGCC_alpha2 PF08473.9 001299035.1_18529001_3 - 4.4e-27 94.8 0.6 2.3e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.9 001299035.1_18529001_3 - 3.3e-25 88.8 0.2 1.8e-24 86.5 0.0 2.3 2 0 0 2 2 2 1 VWA N-terminal dCache_1 PF02743.16 001299035.1_18529001_3 - 7.4e-18 65.1 0.1 1.1e-14 54.8 0.1 2.8 2 0 0 2 2 2 2 Cache domain VWA PF00092.26 001299035.1_18529001_3 - 1.4e-15 57.9 0.1 2.3e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.4 001299035.1_18529001_3 - 3.4e-10 39.9 0.0 1e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.4 001299035.1_18529001_3 - 2.4e-08 34.5 0.1 5.1e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Cache_3-Cache_2 PF17201.2 001299035.1_18529001_3 - 0.0014 17.8 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain ECH_1 PF00378.18 135479.5_18523001_2 - 1.3e-44 152.3 0.0 1.5e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.3 135479.5_18523001_2 - 6.9e-12 45.4 0.0 8.3e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.16 135479.5_18523001_2 - 4.8e-05 23.2 0.0 0.05 13.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 TPR_1 PF00515.26 001273572.1_18526001_1 - 1e-30 104.1 24.2 3.3e-05 23.4 0.0 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.15 001273572.1_18526001_1 - 1.2e-27 93.6 20.8 1.9e-05 24.3 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.29 001273572.1_18526001_1 - 1.5e-22 79.3 3.3 1.5e-22 79.3 3.3 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.4 001273572.1_18526001_1 - 5e-15 55.6 12.6 0.036 14.5 1.1 6.5 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.4 001273572.1_18526001_1 - 5.3e-15 54.2 15.2 0.0018 18.2 0.1 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.4 001273572.1_18526001_1 - 1.4e-14 54.0 17.0 0.0045 17.1 1.7 6.2 3 2 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.4 001273572.1_18526001_1 - 5.2e-13 48.3 11.5 0.0022 17.5 2.4 6.6 5 2 1 6 6 6 3 TPR repeat ANAPC3 PF12895.5 001273572.1_18526001_1 - 5.2e-12 45.7 23.3 1.3e-05 25.2 1.5 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.4 001273572.1_18526001_1 - 2.9e-11 43.7 10.5 0.0047 17.4 0.6 6.0 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.4 001273572.1_18526001_1 - 1.5e-10 40.9 7.1 0.0018 18.2 0.6 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.4 001273572.1_18526001_1 - 3.3e-09 36.6 10.2 0.085 13.6 0.0 7.7 7 1 2 9 9 7 3 Tetratricopeptide repeat TPR_10 PF13374.4 001273572.1_18526001_1 - 7.7e-07 28.7 14.9 1.3 8.9 0.0 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.4 001273572.1_18526001_1 - 1.5e-06 28.0 11.1 0.79 10.1 1.5 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.4 001273572.1_18526001_1 - 1.9e-05 24.8 5.2 3.1 8.5 0.1 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.4 001273572.1_18526001_1 - 4.7e-05 23.0 5.2 0.056 13.4 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.3 001273572.1_18526001_1 - 0.0039 17.1 9.9 0.19 11.6 0.7 4.5 1 1 1 3 3 3 1 Putative TPR-like repeat RPT PF13446.4 001273572.1_18526001_1 - 0.022 14.5 0.0 0.24 11.2 0.0 2.9 1 0 0 1 1 1 0 A repeated domain in UCH-protein Fis1_TPR_C PF14853.4 001273572.1_18526001_1 - 0.053 13.5 13.3 0.16 12.0 0.9 5.4 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.16 001273572.1_18526001_1 - 0.92 9.5 9.6 0.31 11.0 0.3 4.3 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.7 001273572.1_18526001_1 - 3.4 7.1 10.0 0.96 8.8 0.2 4.4 5 0 0 5 5 5 0 SHNi-TPR YL1 PF05764.11 135631.4_18523001_1 - 6.1e-43 147.6 25.3 6.1e-43 147.6 25.3 1.4 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.9 135631.4_18523001_1 - 2.6e-13 49.3 0.4 6.2e-13 48.1 0.4 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RNA_pol PF00940.17 134721.3_18529001_1 - 4.2e-160 533.0 0.0 8.7e-160 531.9 0.0 1.6 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.4 134721.3_18529001_1 - 2.8e-49 168.2 0.5 2.8e-49 168.2 0.5 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.4 134721.3_18529001_1 - 1.3e-05 25.1 0.1 4.4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.18 134721.3_18529001_1 - 0.00027 20.9 1.0 0.0013 18.7 0.0 2.7 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.4 134721.3_18529001_1 - 0.0007 19.5 0.0 0.0026 17.7 0.0 2.0 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_1 PF12854.5 134721.3_18529001_1 - 0.023 14.3 0.1 0.071 12.7 0.0 1.8 2 0 0 2 2 2 0 PPR repeat zf-H2C2_5 PF13909.4 001273577.1_18525001_1 - 5.3e-12 45.1 16.7 0.00013 21.5 3.4 4.7 4 0 0 4 4 4 4 C2H2-type zinc-finger domain zf-C2H2 PF00096.24 001273577.1_18525001_1 - 9.5e-08 32.0 25.9 0.1 13.0 3.5 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type GAGA PF09237.9 001273577.1_18525001_1 - 0.0012 18.4 2.1 1.3 8.7 0.7 2.7 2 0 0 2 2 2 2 GAGA factor zf-H2C2_2 PF13465.4 001273577.1_18525001_1 - 0.021 15.1 1.5 0.021 15.1 1.5 4.6 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_4 PF13894.4 001273577.1_18525001_1 - 0.29 11.9 25.6 1.2 10.0 2.8 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger wnt PF00110.17 001273258.2_18526001_2 - 6.5e-78 262.2 35.5 1.2e-77 261.3 35.5 1.5 1 0 0 1 1 1 1 wnt family Nup160 PF11715.6 001298903.1_18529001_1 - 2.4e-132 442.2 2.7 3.2e-132 441.8 2.7 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 MVL PF12151.6 001298903.1_18529001_3 - 0.023 14.4 0.3 0.061 13.1 0.3 1.7 1 0 0 1 1 1 0 Mannan-binding protein ABC2_membrane PF01061.22 001038772.2_18526001_1 - 5.3e-33 114.1 30.6 5.3e-33 114.1 30.6 2.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.25 001038772.2_18526001_1 - 2.8e-26 92.5 0.0 4.4e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.4 001038772.2_18526001_1 - 7e-07 29.2 0.1 0.002 17.9 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF258 PF03193.14 001038772.2_18526001_1 - 0.00027 20.8 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.17 001038772.2_18526001_1 - 0.00032 20.1 0.0 0.011 15.0 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.4 001038772.2_18526001_1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.4 001038772.2_18526001_1 - 0.0019 18.6 0.1 0.0019 18.6 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.4 001038772.2_18526001_1 - 0.0052 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.4 001038772.2_18526001_1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.4 001038772.2_18526001_1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.4 001038772.2_18526001_1 - 0.036 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.4 001038772.2_18526001_1 - 0.05 13.2 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.21 001038772.2_18526001_1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.4 001038772.2_18526001_1 - 0.13 12.4 0.0 1.2 9.2 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Phage_holin_3_6 PF07332.9 001038772.2_18526001_1 - 0.28 11.1 4.9 0.89 9.5 0.0 2.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Rhodanese PF00581.18 001273562.2_18524001_1 - 8.2e-10 39.0 0.0 3e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain DUF4201 PF13870.4 001032082.3_18525001_3 - 6.5e-43 146.3 17.3 6.5e-43 146.3 17.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) ATG16 PF08614.9 001032082.3_18525001_3 - 0.0055 16.8 11.9 0.0055 16.8 11.9 3.4 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) OGG_N PF07934.10 001032082.3_18525001_3 - 0.092 12.7 2.3 0.79 9.7 0.2 2.8 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain DUF349 PF03993.10 001032082.3_18525001_3 - 1.2 9.3 15.6 1.1 9.5 3.3 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) FERM_C PF09380.8 135540.2_18525001_3 - 1.9e-18 66.5 0.1 3.5e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.8 135540.2_18525001_3 - 6.1e-17 61.2 0.2 1e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.16 135540.2_18525001_3 - 4.1e-14 52.9 0.0 1.2e-13 51.4 0.0 1.8 2 0 0 2 2 2 1 FERM central domain FA PF08736.9 135540.2_18525001_3 - 7.1e-12 45.1 0.5 1.8e-11 43.8 0.5 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) WRW PF10206.7 135540.2_18525001_3 - 0.056 13.7 1.1 0.29 11.4 0.8 2.2 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f DUF1664 PF07889.10 134734.3_18525001_3 - 0.021 14.7 14.6 1.1 9.1 0.1 5.2 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) GATase_7 PF13537.4 134734.3_18525001_3 - 0.091 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain DUF948 PF06103.9 134734.3_18525001_3 - 0.18 12.0 9.1 13 6.0 0.0 4.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) MbeD_MobD PF04899.10 134734.3_18525001_3 - 0.2 11.7 0.1 0.2 11.7 0.1 4.5 4 0 0 4 4 4 0 MbeD/MobD like Jnk-SapK_ap_N PF09744.7 134734.3_18525001_3 - 0.28 11.2 23.0 0.23 11.5 1.6 3.5 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 VSG_B PF13206.4 134734.3_18525001_3 - 0.34 10.0 7.3 0.76 8.8 7.3 1.6 1 0 0 1 1 1 0 Trypanosomal VSG domain DASH_Dad4 PF08650.8 134734.3_18525001_3 - 1.2 9.1 7.7 11 5.9 0.2 3.5 3 1 0 3 3 3 0 DASH complex subunit Dad4 YvbH_ext PF11724.6 134734.3_18525001_3 - 1.4 9.2 3.3 1.4 9.2 0.4 2.6 2 0 0 2 2 2 0 YvbH-like oligomerisation region Syntaxin-6_N PF09177.9 134734.3_18525001_3 - 2.2 8.8 15.9 2.3 8.7 1.9 5.1 4 2 1 5 5 5 0 Syntaxin 6, N-terminal DUF1993 PF09351.8 134734.3_18525001_3 - 2.7 8.0 8.0 1.2 9.1 1.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) Rootletin PF15035.4 134734.3_18525001_3 - 7.2 6.5 23.9 8.3 6.3 2.6 4.1 3 1 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.10 134734.3_18525001_3 - 7.2 7.2 15.0 18 5.9 0.7 5.4 5 0 0 5 5 4 0 SlyX LPP PF04728.11 134734.3_18525001_3 - 8.3 6.8 13.8 20 5.5 1.7 5.1 3 1 1 4 4 4 0 Lipoprotein leucine-zipper FAT PF02259.21 001273498.1_18529001_1 - 4.7e-118 394.2 2.3 4.7e-118 394.2 2.3 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.25 001273498.1_18529001_1 - 1.1e-75 254.6 0.1 2.3e-75 253.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.6 001273498.1_18529001_1 - 6.5e-58 195.0 7.2 3.1e-55 186.3 0.3 4.7 3 1 1 4 4 4 2 Domain of unknown function (DUF3385) FRB_dom PF08771.9 001273498.1_18529001_1 - 1.4e-42 144.0 0.5 1.4e-42 144.0 0.5 3.6 4 0 0 4 4 3 1 FKBP12-rapamycin binding domain FATC PF02260.18 001273498.1_18529001_1 - 9e-15 54.1 2.3 2.6e-14 52.6 2.3 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.4 001273498.1_18529001_1 - 6.3e-11 42.4 7.5 0.011 15.9 0.0 8.6 11 0 0 11 11 11 2 HEAT repeats HEAT PF02985.20 001273498.1_18529001_1 - 1.2e-06 28.0 4.1 0.42 10.8 0.0 8.4 9 0 0 9 9 9 1 HEAT repeat TPR_2 PF07719.15 001273498.1_18529001_1 - 8.7e-05 22.2 5.3 0.029 14.4 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.26 001273498.1_18529001_1 - 8.9e-05 22.0 0.1 0.068 12.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.5 001273498.1_18529001_1 - 0.00013 22.3 8.3 5.8 7.4 0.1 6.3 7 0 0 7 7 5 1 Vacuolar 14 Fab1-binding region TAF6_C PF07571.11 001273498.1_18529001_1 - 0.00016 21.8 0.0 5.4 7.3 0.0 6.3 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain TPR_7 PF13176.4 001273498.1_18529001_1 - 0.001 18.8 0.7 0.045 13.7 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.4 001273498.1_18529001_1 - 0.011 16.0 3.7 0.031 14.7 0.0 3.7 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.4 001273498.1_18529001_1 - 0.011 16.3 0.1 12 6.9 0.0 5.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Clathrin PF00637.18 001273498.1_18529001_1 - 0.014 15.1 3.3 0.02 14.7 0.9 2.6 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_12 PF13424.4 001273498.1_18529001_1 - 0.018 15.2 0.4 0.096 12.9 0.4 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001273498.1_18529001_1 - 9.5 6.4 8.0 4.1 7.5 0.2 3.6 3 1 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HLH PF00010.24 001273412.1_18527001_2 - 2.3e-12 46.5 1.3 6.7e-12 45.1 1.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_S7 PF00177.19 001273410.1_18522001_2 - 2.9e-41 140.5 0.4 3.8e-41 140.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DSBA PF01323.18 001273410.1_18522001_2 - 0.018 14.7 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain 2-oxoacid_dh PF00198.21 135274.2_18525001_3 - 3.3e-80 268.8 0.2 4.3e-80 268.4 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.20 135274.2_18525001_3 - 6.9e-18 64.1 0.1 1.8e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.15 135274.2_18525001_3 - 0.0022 18.2 0.0 0.0047 17.1 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain PBP PF01161.18 057650.3_18522001_3 - 9.6e-15 54.9 0.0 1.3e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RRM_1 PF00076.20 205967.2_18522001_3 - 1.2e-21 76.2 0.0 1.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 205967.2_18522001_3 - 2e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2457 PF10446.7 205967.2_18522001_3 - 3.3 6.7 9.1 3.9 6.4 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) THRAP3_BCLAF1 PF15440.4 205967.2_18522001_3 - 7.9 5.2 32.5 12 4.7 32.5 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family HLH PF00010.24 001299088.1_18523001_2 - 2e-14 53.1 0.6 2e-14 53.1 0.6 2.4 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain Noggin PF05806.10 057419.3_18522001_2 - 2.1e-07 31.0 2.8 7.9e-07 29.1 2.8 1.8 1 1 0 1 1 1 1 Noggin RRM_1 PF00076.20 057653.3_18522001_2 - 5.7e-16 58.0 0.0 1.1e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 057653.3_18522001_2 - 4.9e-07 29.3 0.0 7.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 057653.3_18522001_2 - 0.00091 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif IRS PF02174.15 001201843.2_18527001_1 - 5.9e-28 96.6 0.0 1.2e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) LST1 PF05083.11 001201843.2_18527001_1 - 0.089 13.0 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 LST-1 protein PCRF PF03462.16 135773.3_18523001_1 - 5.6e-45 153.4 2.4 5.6e-45 153.4 2.4 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.18 135773.3_18523001_1 - 2.6e-35 120.7 6.2 2.6e-35 120.7 6.2 2.1 2 0 0 2 2 2 1 RF-1 domain MIR PF02815.17 135773.3_18523001_1 - 0.022 14.5 0.7 0.033 13.9 0.1 1.6 2 0 0 2 2 2 0 MIR domain SieB PF14163.4 135773.3_18523001_1 - 0.15 11.4 0.4 0.41 10.0 0.3 1.8 1 1 0 1 1 1 0 Super-infection exclusion protein B C2-set_2 PF08205.10 001299110.1_18525001_2 - 4.9e-19 68.1 4.7 1.9e-18 66.2 0.1 3.2 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.4 001299110.1_18525001_2 - 1.5e-10 41.4 1.1 0.0099 16.3 0.1 4.0 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.14 001299110.1_18525001_2 - 2.5e-07 30.5 0.0 0.0015 18.4 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.4 001299110.1_18525001_2 - 0.0001 22.4 0.5 0.0086 16.3 0.1 3.4 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.23 001299110.1_18525001_2 - 0.018 15.1 0.3 0.32 11.1 0.1 3.0 3 0 0 3 3 3 0 Immunoglobulin domain Thioredoxin PF00085.18 001299050.1_18524001_1 - 4.7e-63 209.5 0.0 1.1e-31 108.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.4 001299050.1_18524001_1 - 1.4e-13 51.1 0.0 3.9e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.11 001299050.1_18524001_1 - 2.4e-07 30.3 0.0 0.001 18.3 0.0 2.4 2 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 001299050.1_18524001_1 - 1.1e-06 28.9 1.3 0.062 13.6 0.1 3.9 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001299050.1_18524001_1 - 5.8e-06 26.4 0.0 0.067 13.4 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.4 001299050.1_18524001_1 - 4.4e-05 23.4 0.0 0.23 11.5 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.19 001299050.1_18524001_1 - 0.00016 21.5 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.4 001299050.1_18524001_1 - 0.0012 18.5 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.4 001299050.1_18524001_1 - 0.0047 16.8 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.4 001299050.1_18524001_1 - 0.0076 16.3 0.5 0.8 9.7 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_5 PF13743.4 001299050.1_18524001_1 - 0.0077 15.8 0.0 33 4.0 0.0 3.9 2 2 2 4 4 4 0 Thioredoxin Redoxin PF08534.8 001299050.1_18524001_1 - 0.0095 15.5 0.1 0.32 10.5 0.0 2.4 2 0 0 2 2 2 1 Redoxin DDE_Tnp_1_2 PF13586.4 001299050.1_18524001_1 - 0.024 14.9 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Histone PF00125.22 078755.3_18522001_1 - 5.3e-54 182.0 1.7 9.1e-54 181.3 1.7 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 078755.3_18522001_1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.4 078755.3_18522001_1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.3 078755.3_18522001_1 - 0.013 15.9 1.4 0.03 14.8 1.4 1.5 1 0 0 1 1 1 0 PCNA-associated factor CAP_N PF01213.17 164628.3_18522001_1 - 2 7.7 9.0 2.4 7.4 9.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_L37ae PF01780.17 164628.3_18522001_3 - 2.9e-41 139.3 10.4 3.7e-41 139.0 10.4 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rsm1 PF08600.8 164628.3_18522001_3 - 0.0091 16.0 0.5 0.015 15.3 0.5 1.3 1 0 0 1 1 1 1 Rsm1-like Zn_Tnp_IS1595 PF12760.5 164628.3_18522001_3 - 0.02 14.7 2.0 0.037 13.9 2.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain UPF0544 PF15749.3 164628.3_18522001_3 - 0.13 12.8 3.6 4.9 7.8 1.0 2.5 1 1 2 3 3 3 0 Uncharacterised protein family UPF0544 C1_2 PF03107.14 164628.3_18522001_3 - 0.21 11.8 2.4 0.54 10.5 2.4 1.7 1 1 0 1 1 1 0 C1 domain DUF2053 PF09767.7 135945.3_18523001_3 - 2.1e-59 200.1 4.5 3.8e-59 199.3 4.5 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) TRAP-gamma PF07074.10 135477.3_18522001_3 - 2.7e-84 280.8 4.5 3.3e-84 280.5 4.5 1.1 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF1011 PF06237.10 135477.3_18522001_3 - 0.073 13.3 5.7 0.52 10.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) Ribosomal_S5 PF00333.18 001298856.1_18522001_1 - 3.2e-31 107.0 0.7 6.3e-31 106.1 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.13 001298856.1_18522001_1 - 1.2e-25 88.6 0.1 1.9e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain ATP_synth_reg PF14960.4 001298856.1_18522001_1 - 0.096 12.1 0.6 0.2 11.1 0.6 1.4 1 0 0 1 1 1 0 ATP synthase regulation FoP_duplication PF13865.4 001298856.1_18522001_1 - 4.4 7.8 8.0 9.1 6.8 8.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 JHBP PF06585.9 001273510.2_18523001_2 - 2.9e-60 203.3 0.2 3.4e-60 203.1 0.2 1.0 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) MADF_DNA_bdg PF10545.7 001273574.1_18529001_2 - 1.1e-17 63.9 3.0 1.1e-17 63.9 3.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Piwi PF02171.15 057527.4_18527001_2 - 1.8e-99 332.6 0.2 3.4e-99 331.8 0.2 1.5 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.20 057527.4_18527001_2 - 1.4e-32 112.3 0.5 2.4e-32 111.5 0.5 1.3 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.3 057527.4_18527001_2 - 0.061 13.4 0.0 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 Mid domain of argonaute Gelsolin PF00626.20 165223.3_18527001_2 - 2.5e-28 97.6 0.2 0.00059 19.6 0.0 6.7 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.17 165223.3_18527001_2 - 1.6e-12 47.2 6.1 5.3e-12 45.4 6.1 2.0 1 0 0 1 1 1 1 Villin headpiece domain RHD_DNA_bind PF00554.20 001169530.1_18526001_1 - 2.6e-69 232.3 0.0 2.6e-69 232.3 0.0 2.5 3 0 0 3 3 3 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 001169530.1_18526001_1 - 7.3e-39 131.9 0.0 7.3e-39 131.9 0.0 2.5 3 0 0 3 3 3 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.20 165219.2_18529001_3 - 6.8e-69 231.0 0.0 6.8e-69 231.0 0.0 1.7 2 0 0 2 2 2 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 165219.2_18529001_3 - 7.1e-39 131.9 0.0 1.7e-38 130.7 0.0 1.7 1 0 0 1 1 1 1 Rel homology dimerisation domain Brix PF04427.16 058131.5_18523001_2 - 9.4e-30 104.0 1.1 1.4e-29 103.4 1.1 1.3 1 0 0 1 1 1 1 Brix domain Nop53 PF07767.9 058131.5_18523001_2 - 0.056 12.7 21.3 0.084 12.2 21.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.10 058131.5_18523001_2 - 0.45 8.5 28.9 0.7 7.9 28.9 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.12 058131.5_18523001_2 - 3.6 5.6 22.7 6.2 4.9 22.7 1.4 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.30 135608.3_18524001_1 - 4.4e-29 100.0 20.3 5.4e-06 26.9 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.10 135608.3_18524001_1 - 8.6e-14 51.7 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.5 135608.3_18524001_1 - 0.00073 19.7 5.3 0.71 10.1 0.1 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.4 135608.3_18524001_1 - 0.0058 16.5 0.0 0.85 9.5 0.0 3.8 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region AsnC_trans_reg PF01037.19 135608.3_18524001_1 - 0.079 12.8 0.1 5.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Lrp/AsnC ligand binding domain p450 PF00067.20 135285.3_18524001_2 - 1.3e-98 330.6 0.0 1.8e-98 330.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RHD_DNA_bind PF00554.20 001169528.1_18526001_1 - 3e-59 199.6 0.0 5.4e-59 198.8 0.0 1.4 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 001169528.1_18526001_1 - 7e-37 125.5 0.0 1.6e-36 124.3 0.0 1.7 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.20 001169527.2_18529001_1 - 7.3e-59 198.4 0.0 1.2e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 001169527.2_18529001_1 - 1.6e-36 124.3 0.0 3.1e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain dsrm PF00035.24 001298965.1_18525001_1 - 2.2e-27 95.4 0.0 5e-11 43.0 0.0 3.5 3 0 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.5 001298965.1_18525001_1 - 7.1e-12 45.3 0.1 4.4e-06 26.7 0.1 3.7 3 1 0 3 3 3 3 double strand RNA binding domain from DEAD END PROTEIN 1 Staufen_C PF16482.3 001298965.1_18525001_1 - 1.1e-06 28.7 0.3 3.2e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Staufen C-terminal domain LPP20 PF02169.14 001298965.1_18525001_1 - 0.043 14.0 0.6 0.4 10.9 0.0 2.6 3 0 0 3 3 3 0 LPP20 lipoprotein Myosin_head PF00063.19 164758.2_18529001_1 - 2.4e-238 792.7 0.9 3.7e-238 792.0 0.9 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.15 164758.2_18529001_1 - 1.2e-47 160.6 9.9 1.3e-24 86.6 0.1 3.6 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.16 164758.2_18529001_1 - 1.2e-14 54.5 1.1 2.4e-09 37.5 0.0 3.6 3 0 0 3 3 3 2 FERM central domain FERM_N PF09379.8 164758.2_18529001_1 - 4.2e-14 52.1 0.0 1.5e-05 24.7 0.0 3.1 2 0 0 2 2 2 2 FERM N-terminal domain IQ PF00612.25 164758.2_18529001_1 - 4.9e-10 38.2 18.3 0.00095 18.6 4.3 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif ABC_tran PF00005.25 164758.2_18529001_1 - 0.0068 16.8 1.6 0.018 15.4 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_22 PF13401.4 164758.2_18529001_1 - 0.037 14.2 0.0 0.3 11.2 0.0 2.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.4 164758.2_18529001_1 - 0.056 13.7 4.8 0.062 13.5 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain TUDOR PF00567.22 164462.2_18525001_3 - 1.7e-36 124.8 0.3 7.3e-36 122.8 0.1 2.1 2 0 0 2 2 2 1 Tudor domain KH_1 PF00013.27 164462.2_18525001_3 - 5.4e-24 83.7 3.0 3.6e-12 45.8 0.1 2.7 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.3 164462.2_18525001_3 - 0.00041 20.2 0.0 0.0094 15.8 0.0 2.7 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_2 PF07650.15 164462.2_18525001_3 - 0.0056 16.4 0.5 0.0056 16.4 0.5 2.3 2 1 0 2 2 2 1 KH domain AATF-Che1 PF13339.4 164462.2_18525001_3 - 0.2 12.2 3.9 13 6.4 0.6 2.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor TUDOR PF00567.22 164463.2_18525001_1 - 1.6e-36 124.9 0.3 6.6e-36 122.9 0.1 2.0 2 0 0 2 2 2 1 Tudor domain KH_1 PF00013.27 164463.2_18525001_1 - 5.4e-24 83.7 3.0 3.4e-12 45.9 0.1 2.5 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.3 164463.2_18525001_1 - 0.00035 20.4 0.0 0.0087 15.9 0.0 2.7 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_2 PF07650.15 164463.2_18525001_1 - 0.0052 16.4 0.5 0.0052 16.4 0.5 2.3 2 1 0 2 2 2 1 KH domain AATF-Che1 PF13339.4 164463.2_18525001_1 - 0.3 11.6 4.4 12 6.5 0.6 2.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor PP2C PF00481.19 164774.3_18526001_2 - 4.9e-57 193.4 0.0 1.4e-49 168.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.4 164774.3_18526001_2 - 0.0009 18.8 0.0 0.018 14.6 0.0 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C Phage_holin_3_5 PF16085.3 164774.3_18526001_2 - 0.14 12.2 0.3 0.27 11.3 0.3 1.3 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III DSPn PF14671.4 001298792.1_18529001_3 - 4.3e-54 182.6 3.1 9.4e-54 181.6 2.5 2.0 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.18 001298792.1_18529001_3 - 2.9e-13 49.6 0.0 1e-12 47.9 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001298792.1_18529001_3 - 0.00039 19.9 0.0 0.0016 17.9 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.4 001298792.1_18529001_3 - 0.0089 16.0 0.1 0.03 14.3 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate CDP-OH_P_transf PF01066.19 001298789.1_18525001_3 - 5.8e-16 58.9 0.1 5.8e-16 58.9 0.1 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2569 PF10754.7 001298789.1_18525001_3 - 0.0046 17.2 2.8 0.0046 17.2 2.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) DEAD PF00270.27 164646.3_18524001_2 - 2.8e-39 134.6 0.1 4.9e-39 133.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 164646.3_18524001_2 - 4.7e-25 88.0 0.5 8.7e-24 83.9 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.13 164646.3_18524001_2 - 2.4e-07 30.8 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.4 164646.3_18524001_2 - 4.6e-06 26.0 0.0 9.3e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Cyt-b5 PF00173.26 001272956.1_18523001_2 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DUF4500 PF14937.4 001272956.1_18523001_2 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Kelch_4 PF13418.4 001298809.1_18529001_2 - 3.6e-42 141.9 16.0 2.1e-07 30.6 0.1 10.5 11 0 0 11 11 10 7 Galactose oxidase, central domain Kelch_5 PF13854.4 001298809.1_18529001_2 - 3.7e-38 128.8 21.7 0.00021 21.1 0.1 12.2 12 0 0 12 12 12 8 Kelch motif Kelch_3 PF13415.4 001298809.1_18529001_2 - 3.3e-37 125.9 21.4 1.4e-06 28.3 0.0 12.2 12 0 0 12 12 12 7 Galactose oxidase, central domain Kelch_6 PF13964.4 001298809.1_18529001_2 - 5.5e-32 108.9 26.0 0.00028 20.9 0.0 12.3 11 1 1 12 12 12 9 Kelch motif Kelch_1 PF01344.23 001298809.1_18529001_2 - 6.3e-23 80.0 20.2 0.0077 15.7 0.5 10.3 9 0 0 9 9 9 7 Kelch motif CUB PF00431.18 001298809.1_18529001_2 - 1.2e-18 67.3 0.2 8.6e-13 48.5 0.1 2.7 2 0 0 2 2 2 2 CUB domain Kelch_2 PF07646.13 001298809.1_18529001_2 - 2.2e-11 43.1 15.3 1.2 9.1 0.0 10.8 11 0 0 11 11 11 3 Kelch motif PSI PF01437.23 001298809.1_18529001_2 - 2.4e-11 43.9 48.5 2.8e-08 34.0 12.7 16.9 16 2 0 16 16 11 9 Plexin repeat Laminin_EGF PF00053.22 001298809.1_18529001_2 - 4.5e-11 42.6 76.4 3.7e-09 36.5 15.4 18.7 15 5 4 20 20 10 4 Laminin EGF domain EGF_CA PF07645.13 001298809.1_18529001_2 - 8.8e-11 41.7 9.0 8.8e-11 41.7 9.0 13.4 11 3 4 15 15 4 2 Calcium-binding EGF domain EGF_3 PF12947.5 001298809.1_18529001_2 - 1.2e-07 31.6 11.5 1.2e-07 31.6 11.5 12.2 10 1 1 12 12 5 2 EGF domain RPE65 PF03055.13 001298809.1_18529001_2 - 0.00084 18.5 0.1 0.035 13.2 0.0 2.2 2 0 0 2 2 2 1 Retinal pigment epithelial membrane protein DUF2052 PF09747.7 135362.4_18523001_1 - 1.8e-54 184.8 10.6 1.8e-54 184.8 10.6 1.9 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Pyridoxal_deC PF00282.17 057440.5_18525001_2 - 6e-108 360.8 0.0 7.7e-108 360.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.17 057440.5_18525001_2 - 1.1e-05 24.5 0.0 2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.19 057440.5_18525001_2 - 0.00013 21.2 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.11 057440.5_18525001_2 - 0.13 10.8 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Pkinase_Tyr PF07714.15 001169440.2_18529001_1 - 1e-92 309.9 0.0 1.5e-92 309.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.14 001169440.2_18529001_1 - 2e-40 136.6 8.1 1.7e-10 40.7 0.0 6.1 7 0 0 7 7 6 5 Immunoglobulin I-set domain Ig_3 PF13927.4 001169440.2_18529001_1 - 2.8e-40 136.7 13.5 7.1e-09 36.0 0.0 7.6 7 0 0 7 7 7 5 Immunoglobulin domain Pkinase PF00069.23 001169440.2_18529001_1 - 6.4e-38 130.5 0.3 4.9e-26 91.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain ig PF00047.23 001169440.2_18529001_1 - 5.5e-26 90.4 15.9 1.5e-06 28.1 0.0 7.4 7 1 0 7 7 7 5 Immunoglobulin domain Ig_2 PF13895.4 001169440.2_18529001_1 - 9.3e-23 80.2 9.7 0.00025 21.2 0.1 6.8 6 1 0 6 6 6 4 Immunoglobulin domain V-set PF07686.15 001169440.2_18529001_1 - 5.4e-17 61.8 18.0 9.6e-07 28.8 1.2 7.2 7 2 2 9 9 9 4 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.13 001169440.2_18529001_1 - 6.1e-06 25.8 9.2 0.091 12.4 0.4 4.7 4 0 0 4 4 4 2 Adenovirus E3 region protein CR1 C2-set_2 PF08205.10 001169440.2_18529001_1 - 0.00016 21.5 0.2 0.77 9.7 0.0 3.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.3 001169440.2_18529001_1 - 0.00033 20.5 2.0 0.52 10.3 0.0 4.8 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 001169440.2_18529001_1 - 0.025 14.7 0.1 0.57 10.3 0.0 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Kinase-like PF14531.4 001169440.2_18529001_1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like C1-set PF07654.13 001169440.2_18529001_1 - 0.14 12.5 6.7 0.18 12.2 0.1 3.8 4 0 0 4 4 4 0 Immunoglobulin C1-set domain Pkinase_Tyr PF07714.15 001273305.1_18529001_1 - 9.9e-93 310.0 0.0 1.4e-92 309.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.14 001273305.1_18529001_1 - 5.7e-41 138.4 6.9 1.6e-10 40.8 0.0 6.1 7 0 0 7 7 6 5 Immunoglobulin I-set domain Ig_3 PF13927.4 001273305.1_18529001_1 - 1.1e-40 138.0 12.9 6.8e-09 36.1 0.0 7.6 7 0 0 7 7 7 5 Immunoglobulin domain Pkinase PF00069.23 001273305.1_18529001_1 - 5.9e-38 130.6 0.3 4.7e-26 91.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain ig PF00047.23 001273305.1_18529001_1 - 4.6e-26 90.7 15.9 1.5e-06 28.2 0.0 7.4 7 1 0 7 7 7 5 Immunoglobulin domain Ig_2 PF13895.4 001273305.1_18529001_1 - 3.2e-23 81.7 10.3 0.00024 21.2 0.1 6.6 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.15 001273305.1_18529001_1 - 9.2e-17 61.0 16.9 9.2e-07 28.9 1.2 7.1 7 2 2 9 9 9 4 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.13 001273305.1_18529001_1 - 5.2e-06 26.0 9.2 0.088 12.5 0.4 4.7 4 0 0 4 4 4 2 Adenovirus E3 region protein CR1 C2-set_2 PF08205.10 001273305.1_18529001_1 - 0.00014 21.7 0.2 0.75 9.8 0.0 3.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.3 001273305.1_18529001_1 - 0.00028 20.7 2.0 0.5 10.3 0.0 4.8 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 001273305.1_18529001_1 - 0.023 14.8 0.1 0.55 10.3 0.0 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Kinase-like PF14531.4 001273305.1_18529001_1 - 0.07 12.3 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like C1-set PF07654.13 001273305.1_18529001_1 - 0.12 12.7 6.7 0.17 12.2 0.1 3.8 4 0 0 4 4 4 0 Immunoglobulin C1-set domain dCMP_cyt_deam_1 PF00383.21 001273304.1_18523001_2 - 2.1e-15 56.3 0.0 3.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.10 001273304.1_18523001_2 - 7.6e-09 35.8 0.1 1.2e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.4 001273304.1_18523001_2 - 0.005 16.3 0.6 0.51 9.8 0.1 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases AF-4 PF05110.11 001273044.1_18529001_2 - 1.2e-43 149.5 5.6 1.2e-43 149.5 5.6 7.1 4 2 2 8 8 8 2 AF-4 proto-oncoprotein IFT57 PF10498.7 134948.2_18523001_1 - 1.2e-106 356.6 18.4 1.5e-106 356.2 18.4 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 LPP PF04728.11 134948.2_18523001_1 - 1.6 9.0 6.3 6.6 7.1 1.6 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.9 134948.2_18523001_1 - 2.2 8.5 8.6 1.5 9.0 1.0 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Trypsin PF00089.24 135038.2_18522001_2 - 1e-48 165.9 3.9 1.4e-48 165.4 3.9 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 135038.2_18522001_2 - 0.0035 18.1 4.1 0.016 15.9 2.7 2.4 2 1 0 2 2 2 1 Trypsin-like peptidase domain Thioredoxin_7 PF13899.4 135047.4_18524001_3 - 3.8e-13 49.3 0.1 7e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.4 135047.4_18524001_3 - 4.8e-08 32.6 0.4 1.2e-07 31.3 0.4 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.18 135047.4_18524001_3 - 4.3e-07 29.9 0.0 8.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain EST1_DNA_bind PF10373.7 001298985.1_18529001_2 - 2.7e-36 125.4 8.9 9.8e-35 120.3 1.0 3.1 3 0 0 3 3 3 2 Est1 DNA/RNA binding domain EST1 PF10374.7 001298985.1_18529001_2 - 1.1e-16 61.5 0.2 1.1e-16 61.5 0.2 2.7 3 0 0 3 3 3 1 Telomerase activating protein Est1 PIN_4 PF13638.4 001298985.1_18529001_2 - 9.1e-08 32.4 0.3 3.2e-07 30.6 0.3 2.0 1 0 0 1 1 1 1 PIN domain RRF_GI PF12614.6 001298985.1_18529001_2 - 0.048 13.7 0.4 0.18 11.8 0.4 2.0 1 0 0 1 1 1 0 Ribosome recycling factor Ins_allergen_rp PF06757.11 001298718.1_18523001_2 - 9.1e-32 110.3 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Insect allergen related repeat, nitrile-specifier detoxification Mito_carr PF00153.25 135132.3_18523001_1 - 5.6e-59 196.0 0.3 2.2e-19 69.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GATase_5 PF13507.4 164675.2_18529001_2 - 4.8e-98 327.3 0.0 7.2e-98 326.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.20 164675.2_18529001_2 - 6.1e-35 120.5 0.7 8.6e-21 74.6 0.2 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.22 164675.2_18529001_2 - 2.4e-06 28.0 0.3 0.00027 21.4 0.1 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain RCC1 PF00415.16 001298726.1_18525001_1 - 4.6e-48 161.5 1.6 3.1e-08 34.0 0.2 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 001298726.1_18525001_1 - 2.4e-22 78.1 1.3 2.1e-07 30.4 0.1 6.4 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat PBP1_TM PF14812.4 001298726.1_18525001_1 - 0.21 11.9 1.7 0.43 10.9 1.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.30 001298736.1_18524001_1 - 6.1e-06 26.8 4.8 2.1 9.2 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Aconitase PF00330.18 001299190.1_18527001_2 - 1.6e-154 515.1 0.0 2.3e-154 514.7 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.17 001299190.1_18527001_2 - 1.2e-42 145.3 0.0 2e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain adh_short PF00106.23 001299190.1_18527001_2 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Complex1_LYR_2 PF13233.4 135798.3_18522001_1 - 2.2e-09 37.8 0.2 3.1e-09 37.3 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.13 135798.3_18522001_1 - 8.2e-05 22.5 3.1 0.00015 21.6 3.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF678 PF05077.10 135798.3_18522001_2 - 0.039 13.9 8.9 0.074 13.1 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF678) CoA_transf_3 PF02515.15 001273709.1_18523001_2 - 2.2e-75 254.0 0.0 6.5e-75 252.4 0.0 1.6 1 1 0 1 1 1 1 CoA-transferase family III 2-Hacid_dh_C PF02826.17 001201930.2_18523001_3 - 3e-56 189.4 0.0 4.2e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.28 001201930.2_18523001_3 - 7.7e-27 93.5 0.0 1e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.15 001201930.2_18523001_3 - 0.0003 21.2 0.0 0.00056 20.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.13 001201930.2_18523001_3 - 0.0011 19.0 0.1 0.0019 18.3 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.10 001201930.2_18523001_3 - 0.015 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Tetraspannin PF00335.18 078792.3_18523001_3 - 1.4e-36 126.2 11.7 1.7e-36 125.9 11.7 1.1 1 0 0 1 1 1 1 Tetraspanin family SNN_transmemb PF09049.8 078792.3_18523001_3 - 0.072 12.9 1.6 0.38 10.6 1.6 2.3 1 0 0 1 1 1 0 Stannin transmembrane PCI PF01399.25 001298842.1_18524001_3 - 3.9e-25 88.3 1.7 3.9e-25 88.3 1.7 2.5 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.4 001298842.1_18524001_3 - 0.041 13.8 1.6 40 4.5 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat CCM2_C PF16545.3 001298842.1_18524001_3 - 0.047 14.1 1.7 0.18 12.2 0.0 2.4 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology Peptidase_M15_2 PF05951.11 001298842.1_18524001_3 - 0.11 12.0 0.6 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) TPR_1 PF00515.26 001298842.1_18524001_3 - 0.62 9.9 4.2 15 5.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.12 135433.4_18522001_2 - 0.11 10.6 14.7 0.13 10.5 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF563 PF04577.12 134834.3_18524001_1 - 4.8e-33 114.9 0.6 7.3e-33 114.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) OAF PF14941.4 057692.2_18527001_1 - 1.4e-110 368.3 1.7 2e-110 367.8 1.7 1.2 1 0 0 1 1 1 1 Transcriptional regulator, Out at first Spt20 PF12090.6 057692.2_18527001_1 - 0.022 14.2 13.3 0.16 11.5 0.1 2.2 2 0 0 2 2 2 0 Spt20 family DUF755 PF05501.9 057692.2_18527001_1 - 0.022 14.9 16.3 0.06 13.5 16.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.7 057692.2_18527001_1 - 6.5 6.2 17.4 11 5.4 17.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TGF_beta PF00019.18 164488.2_18527001_1 - 7.8e-33 113.4 0.6 7.8e-33 113.4 0.6 2.1 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 164488.2_18527001_1 - 1.1e-32 113.6 0.5 1.1e-32 113.6 0.5 2.0 2 0 0 2 2 2 1 TGF-beta propeptide TFIIA PF03153.11 134862.4_18522001_1 - 4.4 7.0 29.1 5.9 6.6 29.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAD_M PF08527.8 134862.4_18522001_2 - 0.89 9.1 3.9 1.3 8.5 3.9 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Pkinase PF00069.23 134853.2_18523001_1 - 3.1e-29 102.0 0.0 4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 134853.2_18523001_1 - 2.9e-16 59.4 0.0 3.6e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.14 134853.2_18523001_1 - 0.043 13.8 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.12 134853.2_18523001_1 - 0.054 12.7 0.3 0.083 12.1 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2 PF00096.24 080527.3_18526001_2 - 7.3e-06 26.0 11.9 0.0001 22.4 2.1 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 080527.3_18526001_2 - 0.00048 19.9 8.4 0.0087 15.9 0.3 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.4 080527.3_18526001_2 - 0.00098 19.3 0.5 0.00098 19.3 0.5 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.4 080527.3_18526001_2 - 0.0016 18.9 7.1 0.0064 17.1 1.4 4.5 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 080527.3_18526001_2 - 0.025 14.7 1.0 0.025 14.7 1.0 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 080527.3_18526001_2 - 2 8.8 19.1 0.77 10.1 1.7 4.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CRAL_TRIO PF00650.18 001273652.1_18523001_3 - 3.5e-32 111.2 0.0 5.8e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.4 001273652.1_18523001_3 - 7e-06 26.1 0.1 1.3e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.13 001273652.1_18523001_3 - 0.014 15.5 0.1 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.18 165301.2_18524001_1 - 7e-32 110.2 0.0 1.2e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.4 165301.2_18524001_1 - 1.2e-05 25.3 0.1 2.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.13 165301.2_18524001_1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Nup35_RRM_2 PF14605.4 001273657.1_18529001_3 - 2e-18 66.0 0.1 6.2e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.15 001273657.1_18529001_3 - 8.9e-08 32.2 0.3 2.2e-07 30.9 0.3 1.7 1 0 0 1 1 1 1 PWI domain Nup35_RRM PF05172.11 001273657.1_18529001_3 - 0.0012 18.6 0.0 0.031 14.1 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.20 001273657.1_18529001_3 - 0.0012 18.4 0.1 0.0046 16.6 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.22 001273657.1_18529001_3 - 0.003 17.3 0.9 0.0055 16.5 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) OmpH PF03938.12 001273657.1_18529001_3 - 1.8 8.4 35.0 0.34 10.8 0.8 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Sushi PF00084.18 001144368.2_18523001_1 - 1.5e-23 83.0 18.6 5.3e-09 36.4 8.6 3.5 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) WAP PF00095.19 001144368.2_18523001_1 - 4.7e-05 23.6 15.7 4.7e-05 23.6 15.7 4.2 4 2 0 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Sporozoite_P67 PF05642.9 001144368.2_18523001_1 - 0.19 9.7 0.1 0.24 9.3 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CTU2 PF10288.7 136131.4_18523001_2 - 7e-18 64.8 0.4 7e-18 64.8 0.4 1.9 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 HypA PF01155.17 136131.4_18523001_2 - 0.63 9.9 4.6 0.61 10.0 0.1 2.8 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S26e PF01283.17 078871.6_18522001_2 - 1e-52 176.9 8.0 1e-52 176.9 8.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S26e zf-C2H2 PF00096.24 001299130.1_18528001_1 - 3.8e-17 61.6 20.4 6.2e-07 29.4 1.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001299130.1_18528001_1 - 5.2e-16 58.1 21.7 8.2e-08 32.2 1.9 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 001299130.1_18528001_1 - 1.2e-12 47.4 17.9 0.00041 20.8 1.0 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.4 001299130.1_18528001_1 - 4.7e-09 35.7 11.8 0.00064 19.3 2.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.4 001299130.1_18528001_1 - 3.5e-06 26.7 13.4 0.007 16.2 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.13 001299130.1_18528001_1 - 8.5e-06 25.6 14.3 0.0079 16.1 0.3 3.6 1 1 2 3 3 3 2 BED zinc finger GAGA PF09237.9 001299130.1_18528001_1 - 0.00018 21.1 6.4 0.47 10.2 0.6 3.7 1 1 2 3 3 3 3 GAGA factor zf-C2H2_11 PF16622.3 001299130.1_18528001_1 - 0.002 17.7 11.5 0.19 11.4 0.3 3.7 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-Di19 PF05605.10 001299130.1_18528001_1 - 0.0029 17.7 8.3 0.024 14.8 3.4 2.7 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.13 001299130.1_18528001_1 - 0.0081 15.9 10.4 0.23 11.3 0.9 3.7 2 1 1 3 3 3 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.6 001299130.1_18528001_1 - 0.02 15.1 20.2 0.31 11.3 0.1 4.1 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding A2L_zn_ribbon PF08792.8 001299130.1_18528001_1 - 0.024 14.2 0.8 0.85 9.3 0.0 2.8 2 0 0 2 2 2 0 A2L zinc ribbon domain SUIM_assoc PF16619.3 001299130.1_18528001_1 - 0.16 11.9 20.9 0.014 15.4 13.6 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-met PF12874.5 001299130.1_18528001_1 - 0.23 11.7 17.4 1.2 9.5 1.5 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PNISR PF15996.3 001299130.1_18528001_1 - 1.9 8.5 16.8 0.053 13.6 8.9 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR TFIIA PF03153.11 001299130.1_18528001_1 - 2.7 7.8 25.4 0.64 9.8 16.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.9 001299130.1_18528001_1 - 3.4 7.5 6.7 6.7 6.6 6.7 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region XRN_N PF03159.16 001273237.1_18526001_3 - 1.1e-100 335.9 0.0 1.1e-100 335.9 0.0 2.3 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus RRM_1 PF00076.20 164721.3_18525001_1 - 4.1e-34 116.1 0.4 4.8e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 164721.3_18525001_1 - 7.9e-15 54.6 0.1 1.2e-07 31.6 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif XPG_I PF00867.16 057797.4_18525001_1 - 5e-21 74.7 0.1 2.6e-20 72.5 0.1 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.15 057797.4_18525001_1 - 8.7e-21 74.2 0.0 7e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.5 057797.4_18525001_1 - 0.0075 15.6 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 XPG domain containing OrfB_IS605 PF01385.17 057797.4_18525001_1 - 0.055 13.6 3.3 0.081 13.1 0.3 2.3 2 0 0 2 2 2 0 Probable transposase TPR_4 PF07721.12 057797.4_18525001_1 - 0.35 11.5 2.0 1.4 9.7 2.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Enolase_C PF00113.20 164431.3_18525001_2 - 3.9e-158 525.2 0.1 5.5e-158 524.7 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.14 164431.3_18525001_2 - 2.7e-57 192.4 0.1 4.5e-57 191.7 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.4 164431.3_18525001_2 - 9.8e-06 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.9 164431.3_18525001_2 - 0.00071 18.7 0.7 0.0016 17.5 0.1 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Peptidase_M2 PF01401.16 057847.4_18525001_1 - 1.1e-221 737.4 3.9 1.2e-221 737.1 3.9 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Chorion_2 PF03964.13 057847.4_18525001_1 - 0.049 14.3 0.9 0.12 13.1 0.9 1.6 1 0 0 1 1 1 0 Chorion family 2 SUZ PF12752.5 164727.2_18524001_2 - 5e-10 39.8 3.0 5e-10 39.8 3.0 4.3 3 1 0 3 3 3 2 SUZ domain SUZ-C PF12901.5 164727.2_18524001_2 - 2.5e-07 30.4 1.4 2.5e-07 30.4 1.4 2.4 2 0 0 2 2 2 1 SUZ-C motif SUIM_assoc PF16619.3 164727.2_18524001_2 - 0.021 14.8 0.3 0.021 14.8 0.3 4.9 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Pkinase_Tyr PF07714.15 164756.3_18526001_3 - 0.0008 18.6 0.0 0.025 13.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PT PF04886.10 164785.2_18529001_2 - 0.22 11.0 7.1 0.69 9.4 7.1 1.8 1 0 0 1 1 1 0 PT repeat Ig_3 PF13927.4 164785.2_18529001_3 - 1.1e-17 64.3 0.1 3.3e-09 37.1 0.1 3.0 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 164785.2_18529001_3 - 3e-14 52.8 0.9 5.3e-08 32.8 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.14 164785.2_18529001_3 - 5.1e-14 52.0 0.0 5.8e-08 32.6 0.0 2.4 1 1 1 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.4 164785.2_18529001_3 - 4.6e-11 42.8 0.0 3.7e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 164785.2_18529001_3 - 0.014 15.4 0.2 0.23 11.5 0.2 2.8 2 1 0 2 2 2 0 Immunoglobulin V-set domain C1-set PF07654.13 164785.2_18529001_3 - 0.02 15.2 0.3 2.3 8.6 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Phage_CI_C PF16452.3 164785.2_18529001_3 - 0.11 12.6 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor C-terminal domain tRNA-synt_2 PF00152.18 136104.4_18524001_2 - 8.9e-102 340.2 0.0 1.2e-101 339.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.23 136104.4_18524001_2 - 1.7e-13 50.3 0.0 3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.4 136104.4_18524001_2 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF1565 PF07602.9 136104.4_18524001_2 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) HA2 PF04408.21 136102.4_18526001_3 - 4.5e-25 87.8 0.1 2.3e-24 85.5 0.1 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.14 136102.4_18526001_3 - 4.2e-23 81.5 0.0 1.4e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.29 136102.4_18526001_3 - 1.3e-12 47.9 0.0 4e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.27 136102.4_18526001_3 - 1.1e-05 25.1 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.4 136102.4_18526001_3 - 0.00013 21.7 0.2 0.00034 20.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.12 136102.4_18526001_3 - 0.00017 21.4 0.1 0.00035 20.5 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_22 PF13401.4 136102.4_18526001_3 - 0.00059 20.0 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.18 136102.4_18526001_3 - 0.0011 18.0 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.4 136102.4_18526001_3 - 0.007 16.6 0.4 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.20 136102.4_18526001_3 - 0.02 14.4 0.1 0.079 12.5 0.1 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.4 136102.4_18526001_3 - 2.5 8.4 0.0 2.5 8.4 0.0 3.3 2 1 1 3 3 1 0 AAA domain TMEM189_B_dmain PF10520.7 136182.2_18524001_3 - 1.5e-74 249.8 7.4 2.2e-74 249.3 7.4 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain bZIP_2 PF07716.13 164905.3_18522001_3 - 2.8e-05 24.0 8.4 4.9e-05 23.2 8.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.19 164905.3_18522001_3 - 0.00049 20.0 7.4 0.001 19.0 7.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor Ubiquitin_2 PF14560.4 165027.2_18525001_1 - 0.099 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Hep_core_N PF08290.9 165027.2_18525001_1 - 0.22 11.4 3.2 0.7 9.8 3.2 1.8 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger EGF_2 PF07974.11 165027.2_18525001_1 - 1.9 8.8 7.4 0.078 13.2 0.9 2.1 2 0 0 2 2 2 0 EGF-like domain Robl_LC7 PF03259.15 136287.4_18521001_1 - 3.7e-22 77.8 0.0 4.6e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.3 136287.4_18521001_1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Peptidase_U32 PF01136.17 136287.4_18521001_1 - 0.092 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family U32 Cpn60_TCP1 PF00118.22 165043.2_18524001_2 - 3.4e-70 236.9 3.5 1.5e-69 234.8 3.5 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fasciclin PF02469.20 176037.3_18529001_2 - 6.8e-46 155.5 2.9 1.1e-23 83.7 0.1 3.3 3 0 0 3 3 3 2 Fasciclin domain Methyltransf_16 PF10294.7 165329.3_18524001_1 - 2.2e-16 60.0 0.0 3.6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.12 165329.3_18524001_1 - 0.00041 19.8 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.4 165329.3_18524001_1 - 0.0022 18.6 0.0 0.0043 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 165329.3_18524001_1 - 0.0038 17.0 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 165329.3_18524001_1 - 0.016 15.8 0.0 0.038 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.10 165329.3_18524001_1 - 0.039 14.5 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SLM4 PF16818.3 165329.3_18524001_1 - 0.39 10.5 2.7 0.56 10.0 1.3 1.9 2 0 0 2 2 2 0 Protein SLM4 Methyltransf_16 PF10294.7 136187.3_18526001_1 - 4.9e-16 58.8 0.0 7.7e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.12 136187.3_18526001_1 - 0.0009 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.4 136187.3_18526001_1 - 0.0088 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 136187.3_18526001_1 - 0.04 14.5 0.0 0.077 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.10 136187.3_18526001_1 - 0.089 13.3 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Myosin_head PF00063.19 165181.3_18529001_1 - 4.2e-280 930.6 0.1 4.2e-280 930.6 0.1 2.7 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.17 165181.3_18529001_1 - 6.3e-169 563.9 262.4 7.7e-169 563.6 262.4 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.17 165181.3_18529001_1 - 2.1e-11 43.3 0.4 4.8e-11 42.2 0.4 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.10 165181.3_18529001_1 - 3.7e-05 23.2 62.9 0.052 12.8 2.8 9.0 1 1 11 12 12 12 8 Reovirus sigma C capsid protein ERM PF00769.17 165181.3_18529001_1 - 4.2e-05 23.4 50.8 0.00018 21.3 17.8 9.8 1 1 8 10 10 10 6 Ezrin/radixin/moesin family IQ PF00612.25 165181.3_18529001_1 - 0.027 14.1 2.2 0.053 13.2 0.3 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif Thionin PF00321.15 136086.6_18529001_2 - 0.68 10.4 3.3 0.4 11.1 0.2 2.3 2 0 0 2 2 2 0 Plant thionin ABC_tran PF00005.25 136086.6_18529001_3 - 1.1e-56 191.0 0.0 4.8e-29 101.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.21 136086.6_18529001_3 - 3.5e-55 187.4 29.0 1.9e-28 99.8 11.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.17 136086.6_18529001_3 - 5.5e-13 48.7 4.9 0.00066 19.0 1.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.4 136086.6_18529001_3 - 1.3e-09 38.2 1.2 0.0061 16.3 0.0 4.3 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.21 136086.6_18529001_3 - 5.7e-09 35.9 0.1 0.00033 20.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.4 136086.6_18529001_3 - 1.9e-08 33.8 0.2 0.0051 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.4 136086.6_18529001_3 - 7.1e-08 32.9 0.0 0.00096 19.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.14 136086.6_18529001_3 - 9.1e-07 28.8 2.9 0.041 13.6 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.4 136086.6_18529001_3 - 1.1e-05 25.9 0.0 0.074 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.21 136086.6_18529001_3 - 2.2e-05 24.5 5.3 0.029 14.3 0.5 2.8 3 0 0 3 3 3 2 Dynamin family AAA_22 PF13401.4 136086.6_18529001_3 - 9.3e-05 22.6 0.0 0.11 12.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.11 136086.6_18529001_3 - 0.00018 20.6 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DUF87 PF01935.15 136086.6_18529001_3 - 0.0014 18.6 0.1 0.23 11.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_15 PF13175.4 136086.6_18529001_3 - 0.0038 16.8 0.2 2.2 7.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain IIGP PF05049.11 136086.6_18529001_3 - 0.0074 15.2 0.2 0.66 8.8 0.1 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Adeno_IVa2 PF02456.13 136086.6_18529001_3 - 0.0078 14.9 0.8 4.6 5.8 0.0 3.2 3 0 0 3 3 3 1 Adenovirus IVa2 protein cobW PF02492.17 136086.6_18529001_3 - 0.011 15.2 0.1 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.11 136086.6_18529001_3 - 0.014 15.5 0.1 2.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.18 136086.6_18529001_3 - 0.015 14.2 0.0 0.34 9.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.4 136086.6_18529001_3 - 0.017 15.5 0.0 7.6 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.10 136086.6_18529001_3 - 0.021 14.0 0.2 3.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.4 136086.6_18529001_3 - 0.025 14.6 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.14 136086.6_18529001_3 - 0.042 12.7 0.1 3.6 6.3 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.4 136086.6_18529001_3 - 0.055 13.0 0.0 8.2 6.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.7 136086.6_18529001_3 - 0.067 12.8 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Guanylate_kin PF00625.19 136086.6_18529001_3 - 0.07 12.7 0.2 2.9 7.4 0.1 2.5 2 0 0 2 2 2 0 Guanylate kinase IstB_IS21 PF01695.15 136086.6_18529001_3 - 0.083 12.5 0.0 19 4.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AIG1 PF04548.14 136086.6_18529001_3 - 0.091 11.9 0.6 4.1 6.5 0.1 2.5 2 0 0 2 2 2 0 AIG1 family TsaE PF02367.15 136086.6_18529001_3 - 0.14 12.1 0.0 3.1 7.7 0.0 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.27 136086.6_18529001_3 - 0.15 12.3 0.1 3.4 8.0 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF1517 PF07466.9 136086.6_18529001_3 - 0.27 10.2 1.3 0.53 9.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) FtsK_SpoIIIE PF01580.16 136086.6_18529001_3 - 0.31 10.2 3.1 5.1 6.2 0.1 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family ACOX PF01756.17 136117.4_18526001_1 - 3.2e-42 144.0 0.1 6.2e-42 143.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.17 136117.4_18526001_1 - 1.4e-17 63.5 0.0 2.7e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.22 136117.4_18526001_1 - 4.1e-05 23.7 1.0 0.00013 22.1 1.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.4 136117.4_18526001_1 - 0.031 14.7 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Pkinase_Tyr PF07714.15 165359.2_18529001_1 - 6.8e-92 307.3 0.0 9.8e-92 306.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 165359.2_18529001_1 - 9.2e-42 143.1 0.0 1.4e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HLH PF00010.24 165368.1_18527001_3 - 3e-15 55.8 1.7 3.6e-13 49.1 0.6 2.9 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain DUF4988 PF16378.3 165368.1_18527001_3 - 0.049 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Histone_H2A_C PF16211.3 165382.3_18521001_2 - 1.6e-21 75.6 1.6 2.8e-21 74.8 1.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.22 165382.3_18521001_2 - 1e-14 54.9 0.0 1.3e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 165382.3_18521001_2 - 1.1e-05 25.5 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CD36 PF01130.19 165237.2_18524001_2 - 5.2e-129 430.6 0.0 6.1e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 CD36 family Neurensin PF14927.4 165237.2_18524001_2 - 0.12 12.0 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Neurensin zf-C3HC4_3 PF13920.4 001169425.2_18522001_2 - 0.15 11.8 5.9 0.27 11.0 5.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.22 001169425.2_18522001_2 - 5.9 7.0 9.0 1.4 9.0 5.8 1.7 2 0 0 2 2 2 0 B-box zinc finger DUF3456 PF11938.6 134646.4_18524001_2 - 2.5e-08 34.5 4.0 0.00072 20.0 0.2 2.4 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP EGF_CA PF07645.13 134646.4_18524001_2 - 4.2e-05 23.5 10.6 4.2e-05 23.5 10.6 5.2 4 1 1 5 5 5 1 Calcium-binding EGF domain Laminin_EGF PF00053.22 134646.4_18524001_2 - 0.00077 19.4 13.1 0.00077 19.4 13.1 5.2 2 1 3 5 5 5 1 Laminin EGF domain COX4_pro_2 PF07835.10 134646.4_18524001_2 - 0.25 11.3 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV FAD_binding_1 PF00667.18 001273199.1_18526001_2 - 1.6e-74 250.1 0.0 2.3e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.23 001273199.1_18526001_2 - 1.2e-33 116.2 0.2 1.9e-33 115.5 0.2 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.19 001273199.1_18526001_2 - 3.3e-16 59.7 0.0 1.1e-15 58.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Far-17a_AIG1 PF04750.12 001298616.1_18523001_1 - 1.4e-58 197.4 12.3 1.8e-58 197.1 12.3 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein RNase_P_p30 PF01876.14 001272879.1_18523001_3 - 1.6e-57 194.3 0.0 2e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Homeobox_KN PF05920.9 134658.3_18523001_2 - 3.1e-15 55.7 5.2 6.7e-15 54.6 2.0 2.6 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.27 134658.3_18523001_2 - 2.5e-09 36.7 1.9 6.3e-09 35.4 1.9 1.8 1 0 0 1 1 1 1 Homeobox domain TOM6p PF15184.4 134658.3_18523001_2 - 0.11 12.1 0.0 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog Sec7 PF01369.18 001273749.1_18529001_1 - 5.2e-66 221.7 0.0 9e-66 220.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.27 001273749.1_18529001_1 - 3.9e-25 88.2 0.4 9.2e-25 87.1 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 001273749.1_18529001_1 - 3.3e-08 33.8 0.4 3.3e-08 33.8 0.4 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.4 001273749.1_18529001_1 - 0.0074 16.4 0.1 0.48 10.6 0.0 2.5 1 1 0 2 2 2 1 Pleckstrin homology domain NAC PF01849.16 134688.3_18526001_1 - 5.5e-21 74.2 0.0 1.1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 NAC domain PAC3 PF10178.7 134678.3_18522001_1 - 2.9e-24 84.9 0.0 4.1e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 SRCR_2 PF15494.4 134678.3_18522001_2 - 0.037 14.4 0.8 0.068 13.6 0.8 1.4 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Mon1 PF03164.12 135024.2_18524001_3 - 4.3e-134 447.4 9.4 5.1e-134 447.2 9.4 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Mg_trans_NIPA PF05653.12 001273492.1_18523001_2 - 5.5e-145 481.9 18.7 6.6e-145 481.6 18.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.18 001273492.1_18523001_2 - 4.2e-06 26.8 5.3 4.2e-06 26.8 5.3 3.5 3 0 0 3 3 3 2 EamA-like transporter family PhrC_PhrF PF11131.6 001273492.1_18523001_2 - 0.058 12.9 0.2 0.17 11.4 0.2 1.8 1 0 0 1 1 1 0 Rap-phr extracellular signalling NDUF_C2 PF06374.9 134906.2_18521001_2 - 1.7e-43 147.1 0.0 2.1e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Paf1 PF03985.11 001272974.1_18523001_3 - 3.3e-16 59.2 5.2 5.6e-10 38.7 0.1 3.1 2 1 1 3 3 3 3 Paf1 PIG-U PF06728.11 135394.3_18523001_1 - 6.5e-112 374.2 28.0 7.7e-112 374.0 28.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U ThiF PF00899.19 001273327.1_18524001_1 - 2.4e-64 216.9 0.0 3.7e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.18 001273327.1_18524001_1 - 9.8e-12 45.2 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain 2-Hacid_dh_C PF02826.17 001273327.1_18524001_1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAS_11 PF14598.4 001201819.2_18529001_1 - 3.1e-37 127.0 0.0 3.1e-37 127.0 0.0 2.9 2 0 0 2 2 2 1 PAS domain HLH PF00010.24 001201819.2_18529001_1 - 0.002 17.9 0.3 0.0051 16.6 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RskA PF10099.7 001201819.2_18529001_1 - 0.0023 18.1 0.0 0.0023 18.1 0.0 7.8 5 3 3 8 8 8 1 Anti-sigma-K factor rskA PAS_3 PF08447.10 001201819.2_18529001_1 - 0.044 13.9 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 PAS fold PAS PF00989.23 001201819.2_18529001_1 - 0.15 12.0 0.0 0.15 12.0 0.0 3.0 3 0 0 3 3 3 0 PAS fold MIF4G PF02854.17 001169452.2_18526001_2 - 1.7e-41 142.1 0.4 2.8e-41 141.4 0.4 1.3 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.13 001169452.2_18526001_2 - 0.19 11.4 0.4 0.47 10.1 0.4 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Cation_ATPase_N PF00690.24 135967.3_18527001_1 - 0.18 11.4 0.2 11 5.7 0.1 2.6 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus ASC PF00858.22 135965.2_18523001_2 - 2.7e-34 118.7 6.7 4.6e-34 117.9 6.7 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel G0-G1_switch_2 PF15103.4 135965.2_18523001_2 - 0.037 14.3 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 TPR_2 PF07719.15 134680.3_18525001_1 - 1.5e-12 46.5 15.9 1.1 9.4 0.0 9.1 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.4 134680.3_18525001_1 - 7.8e-11 41.2 0.0 0.043 13.9 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.4 134680.3_18525001_1 - 4.8e-10 39.4 13.4 0.054 13.7 1.3 6.4 3 1 5 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.26 134680.3_18525001_1 - 1.2e-07 31.1 13.3 0.0027 17.3 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.4 134680.3_18525001_1 - 1.2e-05 25.6 12.5 0.77 10.2 0.0 6.2 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.4 134680.3_18525001_1 - 5.1e-05 23.7 11.9 0.24 12.0 0.4 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 134680.3_18525001_1 - 0.00013 21.8 2.4 0.31 11.0 0.4 3.4 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.4 134680.3_18525001_1 - 0.0002 21.0 8.6 21 5.3 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.4 134680.3_18525001_1 - 0.0012 19.3 15.5 13 6.8 1.1 7.3 3 1 6 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.4 134680.3_18525001_1 - 0.0014 18.6 9.1 0.33 11.0 0.1 4.3 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.4 134680.3_18525001_1 - 0.0032 17.6 6.4 3 8.3 0.2 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.5 134680.3_18525001_1 - 0.024 14.7 6.8 3.3 7.9 0.8 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.7 134680.3_18525001_1 - 0.087 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_6 PF13174.4 134680.3_18525001_1 - 1.7 9.3 6.7 43 4.9 0.9 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat Arf PF00025.19 134679.2_18522001_3 - 6.5e-20 71.2 0.3 4.9e-15 55.3 0.1 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.18 134679.2_18522001_3 - 7.7e-05 21.9 0.0 0.00049 19.2 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.8 134679.2_18522001_3 - 0.00026 20.3 0.4 0.27 10.5 0.2 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 134679.2_18522001_3 - 0.00061 19.1 0.4 0.0019 17.5 0.4 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.14 134679.2_18522001_3 - 0.04 13.7 0.1 2.5 7.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Roc PF08477.11 134679.2_18522001_3 - 0.049 13.7 0.1 0.26 11.4 0.0 2.1 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NPV_P10 PF05531.10 001272919.1_18522001_2 - 0.11 12.8 0.8 0.35 11.2 0.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CK_II_beta PF01214.16 001272919.1_18522001_2 - 0.44 10.2 2.3 0.3 10.8 0.2 1.6 2 0 0 2 2 2 0 Casein kinase II regulatory subunit DUF848 PF05852.9 001272919.1_18522001_2 - 3 7.8 8.3 1.5 8.8 0.8 2.5 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4407 PF14362.4 001272919.1_18522001_2 - 5 6.3 7.8 6.4 5.9 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sulfotransfer_2 PF03567.12 135076.4_18524001_1 - 2.2e-53 181.6 0.0 3.6e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.4 135076.4_18524001_1 - 0.0081 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family Lipase PF00151.17 001298689.1_18523001_2 - 7.1e-55 186.5 0.0 9.3e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Lipase CAP_N PF01213.17 001273605.2_18527001_1 - 2.4 7.5 6.2 3.7 6.8 6.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SH2 PF00017.22 001273605.2_18527001_2 - 7.3e-10 38.6 0.0 2.1e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.14 001273605.2_18527001_2 - 1.1e-06 28.8 0.1 3.6e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 SOCS box Macoilin PF09726.7 001273605.2_18527001_2 - 0.032 12.7 15.0 0.061 11.7 15.0 1.5 1 0 0 1 1 1 0 Transmembrane protein Astacin PF01400.22 001299029.1_18524001_2 - 1.7e-52 177.7 0.0 2.2e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Lectin_C PF00059.19 001316377.1_18523001_1 - 4.8e-15 56.1 0.2 8.2e-15 55.3 0.2 1.4 1 0 0 1 1 1 1 Lectin C-type domain zf-AD PF07776.13 134994.3_18524001_1 - 7.3e-12 45.2 0.6 2.6e-11 43.5 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) zf-C2H2 PF00096.24 134994.3_18524001_1 - 0.94 9.9 4.9 2.1 8.8 0.3 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 134994.3_18524001_1 - 3.8 8.5 11.5 13 6.8 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger TGF_beta PF00019.18 078737.3_18526001_1 - 7.4e-28 97.4 5.3 1e-27 96.9 3.8 2.1 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 078737.3_18526001_1 - 6.1e-09 35.9 2.8 2.6e-08 33.8 2.8 2.0 1 1 0 1 1 1 1 TGF-beta propeptide DUF667 PF05018.11 164941.2_18522001_3 - 1.1e-81 272.8 0.2 1.4e-81 272.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Rhomboid PF01694.20 001298943.1_18522001_1 - 4.7e-05 23.3 2.5 0.0001 22.2 2.5 1.5 1 0 0 1 1 1 1 Rhomboid family Rhomboid PF01694.20 001298943.1_18522001_3 - 7.6e-19 68.0 6.9 1e-18 67.6 6.9 1.1 1 0 0 1 1 1 1 Rhomboid family ADH_zinc_N_2 PF13602.4 164523.2_18523001_3 - 4.8e-18 66.3 0.0 8.1e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.24 164523.2_18523001_3 - 3e-10 40.0 0.1 2.1e-09 37.2 0.1 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.10 164523.2_18523001_3 - 1.3e-05 24.9 0.0 5.1e-05 23.0 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.15 164523.2_18523001_3 - 0.00062 18.8 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.19 164523.2_18523001_3 - 0.00091 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.19 164523.2_18523001_3 - 0.0094 15.1 0.3 0.015 14.5 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.4 164523.2_18523001_3 - 0.021 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_3 PF03447.14 164523.2_18523001_3 - 0.066 13.7 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Trypsin PF00089.24 001272992.2_18523001_3 - 1.5e-35 122.8 0.0 1.9e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001272992.2_18523001_3 - 0.00016 21.9 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001272992.2_18523001_3 - 0.00087 20.0 0.0 0.0015 19.3 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain CUB PF00431.18 134892.3_18526001_2 - 0.001 19.3 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 CUB domain CDC27 PF09507.8 134892.3_18526001_2 - 0.015 14.6 1.0 0.022 14.0 1.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Methyltransf_12 PF08242.10 001299051.1_18523001_2 - 3.3e-18 66.1 0.0 7.4e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001299051.1_18523001_2 - 4.6e-17 62.4 0.0 5.8e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.10 001299051.1_18523001_2 - 1.2e-15 57.8 0.0 2.2e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.4 001299051.1_18523001_2 - 6.5e-15 55.3 0.0 9.6e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001299051.1_18523001_2 - 2.9e-12 46.5 0.0 4.5e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.16 001299051.1_18523001_2 - 1.9e-10 40.4 0.0 3.7e-10 39.4 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.14 001299051.1_18523001_2 - 0.0035 16.4 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Peptidase_M14 PF00246.22 135466.4_18523001_1 - 3e-85 286.4 0.0 4e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.14 135466.4_18523001_1 - 1.9e-15 56.9 0.1 5e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide G-alpha PF00503.18 001273767.1_18526001_2 - 4.8e-99 331.7 4.9 6.2e-99 331.4 4.9 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001273767.1_18526001_2 - 8.3e-14 51.3 0.3 2.1e-10 40.2 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.4 001273767.1_18526001_2 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2052 PF09747.7 001299057.1_18528001_3 - 0.43 10.6 8.3 0.79 9.7 8.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) zf-C2H2_4 PF13894.4 001299057.1_18528001_3 - 2.1 9.3 9.5 9 7.3 0.2 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger DOR PF14839.4 001299057.1_18528001_3 - 2.2 8.1 17.4 4.5 7.0 17.4 1.4 1 0 0 1 1 1 0 DOR family zf-FCS PF06467.12 001299057.1_18528001_3 - 3 7.7 9.4 0.87 9.5 1.2 2.7 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif EPL1 PF10513.7 001299057.1_18528001_3 - 4.1 7.6 9.7 15 5.9 9.6 2.0 1 1 0 1 1 1 0 Enhancer of polycomb-like Myosin_head PF00063.19 001169519.2_18529001_1 - 2.9e-281 934.5 0.5 2.9e-281 934.5 0.5 2.7 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.17 001169519.2_18529001_1 - 6.5e-169 563.9 262.4 7.8e-169 563.6 262.4 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.17 001169519.2_18529001_1 - 1.8e-12 46.7 0.4 4.2e-12 45.6 0.4 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ERM PF00769.17 001169519.2_18529001_1 - 2.4e-05 24.1 49.8 0.00013 21.8 17.4 9.8 1 1 4 8 8 8 4 Ezrin/radixin/moesin family Reo_sigmaC PF04582.10 001169519.2_18529001_1 - 2.7e-05 23.6 62.4 0.044 13.0 2.7 9.0 1 1 9 11 11 11 6 Reovirus sigma C capsid protein IQ PF00612.25 001169519.2_18529001_1 - 0.026 14.1 2.2 0.053 13.2 0.3 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif NUDIX PF00293.26 001273655.1_18523001_3 - 3.5e-06 26.9 0.0 0.11 12.4 0.2 3.2 2 1 0 2 2 2 2 NUDIX domain PXPV PF12778.5 001273336.1_18529001_1 - 3.5 7.4 9.2 9.7 6.0 9.2 1.7 1 0 0 1 1 1 0 PXPV repeat (3 copies) Sema PF01403.17 001273336.1_18529001_2 - 4.6e-142 473.6 0.0 6.6e-142 473.1 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.23 001273336.1_18529001_2 - 1.8e-06 28.2 5.3 4.8e-06 26.9 5.3 1.8 1 0 0 1 1 1 1 Plexin repeat DEAD PF00270.27 001316393.1_18525001_1 - 1.1e-50 171.7 0.0 1.9e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001316393.1_18525001_1 - 1.5e-32 112.1 0.1 1.5e-30 105.7 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001316393.1_18525001_1 - 1.2e-06 28.4 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.10 001316393.1_18525001_1 - 0.00098 17.9 0.0 0.093 11.3 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.3 001316393.1_18525001_1 - 0.049 12.7 0.1 0.074 12.1 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2693 PF10902.6 001316393.1_18525001_1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) HEM4 PF02602.13 001316393.1_18525001_1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.6 1 1 0 2 2 2 0 Uroporphyrinogen-III synthase HemD MT0933_antitox PF14013.4 001316393.1_18525001_2 - 8.1 6.7 9.7 62 3.9 9.7 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein LRR_6 PF13516.4 001103632.2_18529001_1 - 0.038 13.9 0.1 0.038 13.9 0.1 8.4 10 0 0 10 10 10 0 Leucine Rich repeat LRR_8 PF13855.4 001103632.2_18529001_1 - 0.17 11.5 15.6 10 5.8 2.2 5.2 2 2 2 4 4 4 0 Leucine rich repeat Tho2 PF11262.6 001272976.1_18529001_1 - 6.7e-102 340.6 9.0 6.7e-102 340.6 9.0 2.8 3 0 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.3 001272976.1_18529001_1 - 2.6e-77 260.8 1.7 2.5e-52 178.3 0.7 3.1 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Thoc2 PF11732.6 001272976.1_18529001_1 - 7.4e-29 99.5 0.0 2.5e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Chs3p PF12271.6 001272976.1_18529001_1 - 0.039 13.2 0.1 0.064 12.5 0.1 1.3 1 0 0 1 1 1 0 Chitin synthase III catalytic subunit TMEM215 PF15746.3 001272976.1_18529001_1 - 0.046 13.1 0.5 0.15 11.4 0.5 1.9 1 0 0 1 1 1 0 TMEM215 family ERp29 PF07749.10 001272976.1_18529001_1 - 0.06 14.1 3.5 0.54 11.1 3.5 2.7 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Erf4 PF10256.7 001272976.1_18529001_1 - 0.093 12.7 0.5 0.79 9.7 0.0 2.7 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUF4813 PF16072.3 205964.2_18525001_3 - 9.6e-127 422.5 113.7 2e-108 362.3 77.3 5.9 2 1 4 6 6 6 3 Domain of unknown function (DUF4813) Ig_3 PF13927.4 001201815.2_18527001_2 - 2.5e-35 120.8 0.2 1.2e-13 51.3 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.14 001201815.2_18527001_2 - 2.9e-35 120.1 0.0 3.9e-13 49.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.23 001201815.2_18527001_2 - 2.2e-26 91.7 0.3 1.9e-08 34.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001201815.2_18527001_2 - 6.7e-19 67.9 0.3 1.4e-06 28.5 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001201815.2_18527001_2 - 1.4e-16 60.5 0.1 3.3e-07 30.3 0.1 4.2 3 1 0 3 3 3 3 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001201815.2_18527001_2 - 0.0031 17.4 0.0 0.54 10.2 0.0 3.1 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain tRNA-synt_2 PF00152.18 001273591.1_18528001_2 - 3.1e-94 315.4 0.1 4.3e-94 315.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.23 001273591.1_18528001_2 - 1.1e-19 70.1 0.8 1.2e-06 28.3 0.1 3.5 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain GAD PF02938.12 001273591.1_18528001_2 - 0.051 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 GAD domain tRNA-synt_2b PF00587.23 001273591.1_18528001_2 - 0.15 11.9 0.2 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) GRP PF07172.9 001273591.1_18528001_2 - 0.47 11.1 14.4 1.3 9.6 14.4 1.7 1 0 0 1 1 1 0 Glycine rich protein family CD36 PF01130.19 001201907.2_18523001_2 - 9e-116 387.0 0.4 1.1e-115 386.7 0.4 1.0 1 0 0 1 1 1 1 CD36 family Ig_3 PF13927.4 001298975.1_18526001_3 - 1.1e-32 112.3 0.0 2.9e-12 46.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.14 001298975.1_18526001_3 - 1.7e-30 104.8 0.0 2.6e-09 36.9 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.23 001298975.1_18526001_3 - 1.3e-22 79.7 0.1 3.2e-06 27.1 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001298975.1_18526001_3 - 1.4e-17 63.7 0.2 5e-07 29.8 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.15 001298975.1_18526001_3 - 2.2e-16 59.8 1.8 2.2e-07 30.9 0.2 4.4 3 1 0 3 3 3 3 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001298975.1_18526001_3 - 0.011 15.7 0.1 2.9 7.9 0.0 2.8 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain CRAL_TRIO PF00650.18 001273544.1_18523001_2 - 3.6e-20 72.2 0.1 5.5e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain ELM2 PF01448.22 001201837.2_18523001_1 - 0.00078 20.0 0.8 0.0013 19.3 0.8 1.4 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.29 001201837.2_18523001_1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001201837.2_18523001_1 - 0.092 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Myb DNA-binding like DUF1466 PF07326.9 001201837.2_18523001_2 - 0.56 9.9 3.7 0.78 9.5 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) DUF229 PF02995.15 176000.2_18524001_3 - 7.7e-147 489.7 6.2 7.7e-147 489.7 6.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.21 176000.2_18524001_3 - 0.00049 19.5 0.0 0.068 12.4 0.0 2.3 2 0 0 2 2 2 2 Sulfatase DUF608 PF04685.11 001298999.1_18527001_1 - 4.7e-169 562.1 7.6 6.3e-169 561.7 7.6 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.6 001298999.1_18527001_1 - 3.4e-100 335.3 0.0 5.1e-100 334.7 0.0 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Reticulon PF02453.15 175973.3_18523001_1 - 2.3e-44 150.9 5.2 2.3e-44 150.9 5.2 2.1 2 0 0 2 2 2 1 Reticulon Reticulon PF02453.15 001169405.2_18523001_2 - 2.6e-44 150.8 5.2 2.6e-44 150.8 5.2 2.6 3 0 0 3 3 3 1 Reticulon BRX PF08381.9 001273020.2_18528001_2 - 0.032 13.5 0.1 0.09 12.0 0.1 1.7 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 DUF1091 PF06477.11 175990.1_18522001_3 - 0.04 14.3 0.4 0.07 13.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) DUF1091 PF06477.11 206014.2_18522001_1 - 2.3e-06 27.8 0.1 3.7e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1091) EcKinase PF02958.18 001014494.2_18523001_1 - 1.4e-40 139.3 0.0 2.3e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.9 001014494.2_18523001_1 - 3.9e-15 55.5 0.0 9e-15 54.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.21 001014494.2_18523001_1 - 5.3e-10 39.5 0.0 7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.18 001014494.2_18523001_1 - 0.00044 19.8 0.0 0.0009 18.8 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pneumo_phosprot PF02478.14 001014494.2_18523001_1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Histone_H2A_C PF16211.3 001032195.2_18521001_2 - 1.6e-21 75.6 1.6 2.8e-21 74.8 1.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.22 001032195.2_18521001_2 - 3.1e-15 56.6 0.0 3.8e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001032195.2_18521001_2 - 1.1e-05 25.5 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.4 001032206.1_18522001_1 - 4.9e-08 32.9 0.0 7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.15 001032206.1_18522001_1 - 6.6e-05 22.9 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.4 001032206.1_18522001_1 - 0.00012 22.3 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.22 001032206.1_18522001_1 - 0.00044 20.5 0.1 0.00062 20.0 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001032206.1_18522001_1 - 0.00078 19.6 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.13 001032206.1_18522001_1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.11 001032206.1_18522001_1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated GMAP PF06540.9 001032206.1_18522001_2 - 0.12 12.3 0.2 0.18 11.7 0.2 1.2 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) CENP-T_C PF15511.4 001032161.2_18521001_3 - 2.9e-08 33.7 0.0 3.7e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.15 001032161.2_18521001_3 - 4.4e-05 23.4 0.2 6.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.4 001032161.2_18521001_3 - 7.4e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.22 001032161.2_18521001_3 - 0.00036 20.8 0.3 0.00042 20.6 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001032161.2_18521001_3 - 0.0005 20.2 0.1 0.00077 19.6 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.13 001032161.2_18521001_3 - 0.009 15.9 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.11 001032161.2_18521001_3 - 0.039 13.8 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Chorein_N PF12624.5 001273136.1_18529001_2 - 6.4e-15 55.2 2.0 6.4e-15 55.2 0.1 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 CCDC24 PF15669.3 001273136.1_18529001_2 - 2.8 7.6 7.0 54 3.4 0.0 3.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Chorein_N PF12624.5 001273138.1_18529001_2 - 6.3e-15 55.2 0.1 6.3e-15 55.2 0.1 2.4 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 Ribosomal_L30 PF00327.18 001103682.3_18524001_3 - 0.00026 20.7 0.1 0.00076 19.2 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.10 001103682.3_18524001_3 - 0.11 12.7 5.4 0.22 11.7 5.4 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Pou PF00157.15 001298947.1_18526001_1 - 6.3e-38 128.5 1.2 9.9e-38 127.9 0.1 2.0 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001298947.1_18526001_1 - 1.7e-17 62.8 2.5 1.7e-17 62.8 2.5 2.3 2 0 0 2 2 2 1 Homeobox domain ApbE PF02424.13 001298947.1_18526001_1 - 0.039 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 ApbE family Homeobox_KN PF05920.9 001298947.1_18526001_1 - 0.089 12.6 0.1 0.28 11.0 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain HTH_31 PF13560.4 001298947.1_18526001_1 - 0.12 12.6 0.0 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Spectrin PF00435.19 001201768.2_18529001_1 - 1.9e-132 433.2 859.8 2.6e-08 34.2 0.9 85.0 75 14 16 91 91 91 55 Spectrin repeat CH PF00307.29 001201768.2_18529001_1 - 2.5e-43 146.6 0.0 2.6e-20 72.5 0.0 4.7 2 0 0 2 2 2 2 Calponin homology (CH) domain KASH PF10541.7 001201768.2_18529001_1 - 1.3e-20 73.2 0.8 2.4e-20 72.4 0.8 1.5 1 0 0 1 1 1 1 Nuclear envelope localisation domain CAMSAP_CH PF11971.6 001201768.2_18529001_1 - 0.0052 16.5 0.0 9.6 6.0 0.0 3.8 3 0 0 3 3 3 2 CAMSAP CH domain TRCF PF03461.13 001201768.2_18529001_1 - 0.043 14.1 0.9 3.3 8.0 0.0 5.0 4 0 0 4 4 4 0 TRCF domain DUF3369 PF11849.6 001201768.2_18529001_1 - 0.8 9.7 12.3 0.018 15.1 0.5 4.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) Imm7 PF15585.4 001201768.2_18529001_1 - 7.9 6.7 8.0 17 5.6 0.2 5.8 3 0 0 3 3 3 0 Immunity protein 7 Piezo_RRas_bdg PF12166.6 001201789.2_18529001_1 - 2.4e-128 428.9 0.0 4.7e-128 427.9 0.0 1.5 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.3 001201789.2_18529001_1 - 2.6e-42 144.7 1.1 7.8e-42 143.1 1.1 1.8 1 0 0 1 1 1 1 Piezo DUF3593 PF12159.6 001201789.2_18529001_1 - 0.077 12.9 10.8 0.15 12.0 4.9 3.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) DUF347 PF03988.10 001201789.2_18529001_1 - 0.85 9.7 8.3 8.8 6.5 8.3 3.0 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF4750 PF15938.3 001201789.2_18529001_3 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) HCO3_cotransp PF00955.19 001273252.1_18529001_3 - 6.7e-224 744.3 10.6 9e-224 743.9 10.6 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.11 001273252.1_18529001_3 - 5e-105 351.0 0.0 7.8e-105 350.4 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain MFS_MOT1 PF16983.3 001273252.1_18529001_3 - 4.9 7.2 7.7 4.2 7.5 0.4 2.9 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF4574 PF15141.4 001144295.2_18522001_2 - 8.4e-23 80.0 0.0 1.2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4574) Guanylate_kin PF00625.19 001273446.1_18529001_2 - 2.2e-46 157.7 1.0 4.6e-46 156.7 0.1 1.9 2 0 0 2 2 2 1 Guanylate kinase VGCC_beta4Aa_N PF12052.6 001273446.1_18529001_2 - 2.3e-20 72.3 9.0 2.3e-20 72.3 9.0 3.2 3 0 0 3 3 3 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.26 001273446.1_18529001_2 - 0.14 11.7 0.1 0.32 10.5 0.1 1.6 1 0 0 1 1 1 0 SH3 domain HAP PF03866.11 001169486.2_18521001_2 - 0.07 13.0 0.0 0.087 12.7 0.0 1.1 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) Pkinase_Tyr PF07714.15 058001.3_18525001_2 - 0.00051 19.3 0.0 0.02 14.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RNA_pol_Rpb4 PF03874.14 001299164.1_18527001_1 - 0.18 12.0 2.7 0.78 9.9 0.0 2.3 1 1 1 2 2 2 0 RNA polymerase Rpb4 PDEase_I PF00233.17 001144345.3_18529001_3 - 2.1e-81 273.0 2.6 3.5e-81 272.3 2.6 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.10 001144345.3_18529001_3 - 1.4e-32 111.2 0.2 3.4e-32 109.9 0.2 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF1771 PF08590.8 001169498.1_18528001_2 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) DEAD PF00270.27 001273529.2_18525001_2 - 1.1e-50 171.6 0.0 2e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001273529.2_18525001_2 - 1.7e-32 111.9 0.1 1.5e-30 105.6 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001273529.2_18525001_2 - 1.3e-06 28.3 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.10 001273529.2_18525001_2 - 0.0011 17.7 0.0 0.099 11.3 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.3 001273529.2_18525001_2 - 0.052 12.6 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2693 PF10902.6 001273529.2_18525001_2 - 0.072 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) HEM4 PF02602.13 001273529.2_18525001_2 - 0.12 11.6 0.0 0.34 10.1 0.0 1.6 1 1 0 2 2 2 0 Uroporphyrinogen-III synthase HemD MT0933_antitox PF14013.4 001273529.2_18525001_3 - 8.5 6.6 9.6 60 3.9 9.7 2.0 1 1 0 1 1 1 0 MT0933-like antitoxin protein Sporozoite_P67 PF05642.9 135859.4_18529001_2 - 4.5e-08 31.5 0.1 4.5e-08 31.5 0.1 2.4 1 1 1 2 2 2 1 Sporozoite P67 surface antigen TFIIA PF03153.11 135859.4_18529001_2 - 0.093 12.6 20.1 0.036 13.9 11.9 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PHB_acc PF05233.11 047865.1_18525120_1 - 0.19 11.7 0.2 0.37 10.7 0.2 1.4 1 0 0 1 1 1 0 PHB accumulation regulatory domain DUF4796 PF16044.3 073687.1_18523120_3 - 0.033 13.6 0.0 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) G-patch_2 PF12656.5 124054.2_18521120_1 - 0.065 13.2 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 G-patch domain Baculo_LEF-10 PF07206.9 124062.1_18522120_2 - 0.14 12.2 0.6 0.25 11.4 0.2 1.5 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) zf-C2H2_11 PF16622.3 124062.1_18522120_3 - 0.053 13.2 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 zinc-finger C2H2-type DUF2179 PF10035.7 073716.2_18522120_1 - 0.074 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF1242 PF06842.10 073716.2_18522120_2 - 0.15 11.7 11.9 0.59 9.9 0.5 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1242) DUF4821 PF16092.3 073720.1_18522120_3 - 0.017 14.7 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) FAM27 PF15832.3 124076.1_18521120_3 - 2.9 8.4 10.6 1.5 9.3 3.1 2.0 1 1 1 2 2 2 0 FAM27 D and E protein family SMP_LBD PF17047.3 073723.2_18522120_3 - 0.049 13.0 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain zf-C2H2_assoc PF16606.3 047911.1_18523120_3 - 0.12 12.5 0.8 0.2 11.8 0.8 1.3 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers DUF5087 PF17006.3 124129.1_18521120_3 - 0.084 12.3 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) RELT PF12606.6 144653.1_18522120_1 - 2.5 7.4 8.1 4.7 6.5 8.1 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 C_tripleX PF02363.17 124158.1_18521120_2 - 0.17 12.1 0.9 0.17 12.1 0.9 2.5 4 0 0 4 4 4 0 Cysteine rich repeat FCSD-flav_bind PF09242.9 124162.1_18522120_3 - 0.0076 16.5 0.1 0.01 16.0 0.1 1.2 1 0 0 1 1 1 1 Flavocytochrome c sulphide dehydrogenase, flavin-binding Blt1 PF12754.5 073757.1_18522120_3 - 0.086 13.0 0.8 0.13 12.4 0.8 1.3 1 0 0 1 1 1 0 Blt1 N-terminal domain PRIMA1 PF16101.3 124194.1_18521120_1 - 0.3 11.0 4.3 0.38 10.7 4.3 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1655 PF07868.9 124197.1_18528120_2 - 0.084 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) TMEM52 PF14979.4 124204.1_18521120_2 - 6.5 6.5 11.4 8.4 6.2 11.4 1.3 1 0 0 1 1 1 0 Transmembrane 52 DUF4748 PF15932.3 124209.1_18521120_2 - 3.5 7.3 5.4 5.6 6.7 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) SUIM_assoc PF16619.3 124210.1_18521120_1 - 0.0024 17.8 8.0 0.0046 16.9 8.0 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF1815 PF08844.8 124216.1_18523120_2 - 0.025 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) SPT16 PF08644.9 124216.1_18523120_3 - 0.018 15.1 2.7 0.031 14.3 2.7 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) PHD_3 PF13922.4 124227.1_18521120_1 - 0.076 13.3 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx NAS PF03059.14 124240.1_18522120_1 - 0.023 13.9 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Myb_DNA-binding PF00249.29 124241.1_18522120_2 - 0.15 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Colicin_im PF03857.11 124244.1_18521120_3 - 0.047 13.5 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Colicin immunity protein Fer4_9 PF13187.4 124264.1_18522120_1 - 0.019 15.0 3.7 0.041 13.9 3.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-LSD1 PF06943.10 124265.1_18521120_3 - 5.5 6.8 6.1 8.3 6.2 0.1 2.6 3 0 0 3 3 3 0 LSD1 zinc finger DUF1611 PF07755.9 124269.1_18524120_3 - 0.19 10.5 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1611) DUF2225 PF09986.7 124272.1_18522120_2 - 0.046 13.3 0.7 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) AC_N PF16214.3 124272.1_18522120_2 - 0.055 12.5 0.3 0.073 12.1 0.3 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF2905 PF11146.6 073778.1_18522120_3 - 0.72 9.9 4.2 0.36 10.9 0.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2905) PT PF04886.10 073779.1_18522120_1 - 6.1e-08 31.9 16.8 1e-07 31.2 16.8 1.4 1 0 0 1 1 1 1 PT repeat DUF4106 PF13388.4 073779.1_18522120_1 - 6.1 5.8 9.6 8.1 5.4 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PT PF04886.10 073779.1_18522120_2 - 0.00011 21.6 9.4 0.00034 19.9 9.4 1.9 1 0 0 1 1 1 1 PT repeat PT PF04886.10 073779.1_18522120_3 - 2e-06 27.1 13.2 2e-06 27.1 13.2 1.6 2 0 0 2 2 2 1 PT repeat DUF4106 PF13388.4 073779.1_18522120_3 - 1.5 7.8 7.0 0.19 10.8 2.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) Ribosomal_S4e PF00900.18 124286.1_18522120_3 - 0.14 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal family S4e PTAC PF06130.10 073784.2_18524120_3 - 0.035 14.1 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphate propanoyltransferase UreE_N PF02814.13 124315.1_18521120_3 - 0.17 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Phostensin_N PF13916.4 124316.1_18522120_3 - 0.099 12.9 1.7 0.14 12.3 1.7 1.2 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal GETHR PF05671.9 124320.1_18522120_3 - 0.12 11.6 0.8 0.22 10.8 0.8 1.3 1 0 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) ARL6IP6 PF15062.4 124324.1_18521120_1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix K_channel_TID PF07941.9 124330.1_18521120_1 - 0.048 14.0 0.6 0.078 13.3 0.6 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Atrophin-1 PF03154.13 124330.1_18521120_1 - 0.083 11.0 1.4 0.075 11.2 1.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 124330.1_18521120_1 - 0.094 12.6 0.6 0.17 11.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Fer2 PF00111.25 124333.1_18521120_2 - 0.046 13.5 0.6 0.073 12.9 0.6 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain FAM220 PF15487.4 124336.1_18521120_2 - 0.031 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 FAM220 family Neur_chan_memb PF02932.14 124342.1_18521120_2 - 0.45 10.4 3.5 0.5 10.2 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region VMR2 PF17055.3 124350.1_18521120_1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral matrix protein M2 DUF2644 PF10841.6 124366.1_18522120_3 - 0.0058 16.7 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2644) DUF1658 PF07871.9 124369.1_18521120_3 - 0.0077 16.0 2.9 0.021 14.6 2.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1658) Connexin PF00029.17 124379.1_18523120_1 - 5.1 6.7 7.7 2.4 7.8 1.0 2.8 3 0 0 3 3 3 0 Connexin DUF4306 PF14154.4 048019.1_18522120_3 - 0.095 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Fer4_6 PF12837.5 133091.1_18527120_3 - 0.067 13.2 2.3 0.27 11.3 2.3 2.1 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_6 PF12837.5 124396.1_18523120_1 - 0.029 14.4 2.3 0.075 13.0 2.3 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain DUF2894 PF11445.6 124396.1_18523120_1 - 0.065 13.6 1.0 0.089 13.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF4725 PF15854.3 124400.1_18522120_2 - 0.09 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4725) Bunya_G2 PF03563.11 073815.1_18521120_2 - 0.083 12.0 0.5 0.11 11.6 0.5 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 DUF912 PF06024.10 073815.1_18521120_2 - 8.8 6.6 6.0 15 5.8 6.0 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SEC-C PF02810.13 124411.1_18523120_3 - 2.2 8.1 7.5 12 5.8 0.4 2.5 2 0 0 2 2 2 0 SEC-C motif SVIP PF15811.3 124428.1_18523120_2 - 0.066 13.5 3.8 0.14 12.5 3.8 1.5 1 0 0 1 1 1 0 Small VCP/p97-interacting protein DUF2892 PF11127.6 073819.1_18523120_3 - 0.035 14.0 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) P_proprotein PF01483.18 144658.1_18523120_3 - 0.089 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Proprotein convertase P-domain DUF3446 PF11928.6 124432.1_18522120_3 - 0.24 11.6 4.0 0.38 11.0 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Shugoshin_C PF07557.9 133093.1_18522120_3 - 0.25 11.1 5.0 2.1 8.1 0.1 2.9 3 0 0 3 3 3 0 Shugoshin C terminus GPS2_interact PF15784.3 133099.1_18523120_1 - 0.12 12.9 0.1 0.22 12.1 0.1 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain THOC7 PF05615.11 167804.2_18522001_1 - 1.3e-28 99.7 2.3 1.3e-28 99.7 2.3 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 APG6 PF04111.10 167804.2_18522001_1 - 0.17 11.1 11.8 0.25 10.6 11.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Bromodomain PF00439.23 167817.3_18529001_2 - 2.4e-25 88.3 1.3 6.7e-25 86.9 1.3 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.27 167817.3_18529001_2 - 1.5e-23 82.3 54.1 2.2e-09 36.9 6.4 4.2 4 0 0 4 4 4 3 PHD-finger DDT PF02791.15 167817.3_18529001_2 - 9.9e-15 54.5 0.6 2.2e-14 53.4 0.6 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.4 167817.3_18529001_2 - 1.8e-07 30.4 0.0 7.1e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 WSD PF15613.4 167817.3_18529001_2 - 0.0057 17.0 5.1 0.0057 17.0 5.1 4.9 3 2 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif RhoGEF PF00621.18 138180.4_18529001_3 - 2.1e-34 119.2 0.1 4.8e-34 118.0 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.26 138180.4_18529001_3 - 2.2e-05 23.8 0.0 5.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.27 138180.4_18529001_3 - 4.5e-05 23.8 0.4 0.00013 22.3 0.4 1.7 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.4 138180.4_18529001_3 - 0.039 13.7 0.1 0.095 12.4 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain DUF4802 PF16060.3 138180.4_18529001_3 - 0.41 10.7 7.7 1.8 8.6 7.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) zf-C2H2 PF00096.24 138190.2_18529001_1 - 1.3e-13 50.4 79.3 0.00013 22.1 2.0 10.5 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 138190.2_18529001_1 - 3.3e-13 49.1 74.4 0.0011 19.5 1.4 11.0 11 0 0 11 11 11 7 C2H2-type zinc finger zf-H2C2_2 PF13465.4 138190.2_18529001_1 - 2e-08 34.2 54.3 0.0023 18.2 0.8 10.1 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.6 138190.2_18529001_1 - 1.4e-05 25.1 36.7 0.0025 17.9 0.5 7.0 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 138190.2_18529001_1 - 0.01 15.7 1.5 0.01 15.7 1.5 7.2 9 0 0 9 9 9 2 C2H2-type zinc finger DUF2757 PF10955.6 138190.2_18529001_1 - 0.02 15.1 0.5 0.02 15.1 0.5 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2757) zf-H2C2_5 PF13909.4 138190.2_18529001_1 - 0.021 14.4 0.3 0.021 14.4 0.3 8.6 9 0 0 9 9 9 0 C2H2-type zinc-finger domain zf-met PF12874.5 138190.2_18529001_1 - 0.051 13.9 0.5 0.051 13.9 0.5 6.9 8 0 0 8 8 8 0 Zinc-finger of C2H2 type Sugar_tr PF00083.22 138229.2_18529001_2 - 1.6e-134 449.1 18.5 2.1e-134 448.7 18.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 138229.2_18529001_2 - 3.7e-22 78.6 23.6 3.7e-22 78.6 23.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily VPS28 PF03997.10 138229.2_18529001_2 - 0.07 12.7 1.6 0.17 11.4 1.6 1.6 1 0 0 1 1 1 0 VPS28 protein Sugar_tr PF00083.22 167846.3_18526001_1 - 7.1e-98 328.3 9.3 1.2e-97 327.5 9.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 167846.3_18526001_1 - 3.8e-23 81.8 10.4 5.8e-23 81.2 10.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily BLOC1_2 PF10046.7 167846.3_18526001_1 - 0.00061 19.9 3.4 0.0014 18.8 2.9 1.8 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.10 167846.3_18526001_1 - 0.0013 18.6 6.5 0.0028 17.5 6.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) MFS_2 PF13347.4 167846.3_18526001_1 - 0.0056 15.1 5.2 0.067 11.6 0.8 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Spc7 PF08317.9 167846.3_18526001_1 - 0.011 14.6 6.4 0.02 13.7 6.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.10 167846.3_18526001_1 - 0.011 15.6 2.6 0.016 15.1 0.9 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ran-binding PF05508.9 167846.3_18526001_1 - 0.016 14.0 3.3 0.036 12.9 3.3 1.5 1 0 0 1 1 1 0 RanGTP-binding protein DUF812 PF05667.9 167846.3_18526001_1 - 0.019 13.8 4.4 0.046 12.5 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TBPIP PF07106.11 167846.3_18526001_1 - 0.039 13.6 4.3 0.13 11.9 4.3 1.9 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ISG65-75 PF11727.6 167846.3_18526001_1 - 0.068 12.3 1.4 0.12 11.5 1.4 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein T2SSF PF00482.21 167846.3_18526001_1 - 0.07 13.0 3.1 0.19 11.6 0.3 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TMPIT PF07851.11 167846.3_18526001_1 - 0.074 12.1 8.4 0.38 9.8 8.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein Reo_sigmaC PF04582.10 167846.3_18526001_1 - 0.095 11.9 0.8 0.17 11.1 0.8 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein NPV_P10 PF05531.10 167846.3_18526001_1 - 0.29 11.5 3.9 0.39 11.1 1.7 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.11 167846.3_18526001_1 - 0.35 11.4 2.7 1.2 9.6 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF948 PF06103.9 167846.3_18526001_1 - 0.37 11.0 2.0 1.2 9.3 1.6 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.9 167846.3_18526001_1 - 0.38 11.0 6.4 9.6 6.5 2.3 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin_2 PF14523.4 167846.3_18526001_1 - 0.57 10.4 4.6 0.74 10.1 1.8 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Bcr-Abl_Oligo PF09036.8 167846.3_18526001_1 - 1.2 9.1 3.4 2.1 8.3 1.4 2.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Seryl_tRNA_N PF02403.20 167846.3_18526001_1 - 1.3 9.2 8.9 0.059 13.5 2.8 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Swi5 PF07061.9 167846.3_18526001_1 - 1.4 8.9 4.1 0.66 9.9 1.1 2.0 2 0 0 2 2 1 0 Swi5 COG2 PF06148.9 167846.3_18526001_1 - 2.3 8.2 8.1 9.4 6.2 8.2 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.9 167846.3_18526001_1 - 6.9 7.2 10.3 0.4 11.1 4.3 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Vac_Fusion PF02346.14 167846.3_18526001_1 - 8.8 5.9 9.2 24 4.5 1.3 3.3 1 1 3 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF4497 PF14924.4 001031923.2_18527001_3 - 2.1e-07 31.2 0.0 6.2e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4497) 5_nucleotid PF05761.12 138251.3_18525001_2 - 5.3e-60 203.5 0.2 1.8e-59 201.7 0.3 1.7 2 0 0 2 2 2 1 5' nucleotidase family Hydrolase PF00702.24 138251.3_18525001_2 - 0.00016 21.9 0.0 0.0015 18.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.5 138251.3_18525001_2 - 0.028 14.7 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.4 138251.3_18525001_2 - 0.12 12.4 0.0 12 5.8 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF3850 PF12961.5 139375.2_18529001_2 - 0.056 13.5 1.7 0.47 10.6 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3850) Chitin_bind_4 PF00379.21 139410.2_18522001_2 - 4.2e-13 49.5 2.2 4.2e-13 49.5 2.2 1.8 2 0 0 2 2 2 1 Insect cuticle protein SPT16 PF08644.9 167922.3_18528001_3 - 6.3e-60 201.6 0.2 6.3e-60 201.6 0.2 2.4 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.4 167922.3_18528001_3 - 2.1e-46 157.6 0.3 2.1e-46 157.6 0.3 2.4 2 1 1 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.22 167922.3_18528001_3 - 1.5e-29 103.1 0.0 2.3e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.10 167922.3_18528001_3 - 3.9e-17 62.3 0.1 1.1e-16 60.9 0.1 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Gelsolin PF00626.20 206244.3_18529001_3 - 1.2e-24 85.9 0.2 0.0016 18.2 0.0 6.1 6 0 0 6 6 6 5 Gelsolin repeat VHP PF02209.17 206244.3_18529001_3 - 1.3e-15 57.0 0.1 3.9e-15 55.5 0.1 1.9 1 0 0 1 1 1 1 Villin headpiece domain Pkinase PF00069.23 206249.3_18529001_3 - 9.3e-61 205.4 0.0 1.4e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.20 206249.3_18529001_3 - 8e-58 196.1 0.0 1.1e-57 195.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.15 206249.3_18529001_3 - 6.1e-45 153.4 0.0 9.7e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 206249.3_18529001_3 - 0.0019 17.5 0.0 0.0048 16.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.4 206249.3_18529001_3 - 0.12 11.8 5.1 0.15 11.5 0.1 2.9 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 GREB1 PF15782.3 206249.3_18529001_3 - 0.85 6.5 11.3 1.2 6.0 11.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAP PF02037.25 001144406.3_18529001_1 - 2.3e-12 46.2 0.0 5.4e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 SAP domain RPEL PF02755.13 001144406.3_18529001_1 - 8.5e-12 44.2 16.0 2.8e-06 26.7 1.1 3.7 3 0 0 3 3 3 2 RPEL repeat GrpE PF01025.17 001144406.3_18529001_1 - 4 6.9 22.6 0.011 15.2 2.2 2.8 2 0 0 2 2 2 0 GrpE DUF4797 PF16051.3 167980.3_18529001_2 - 1.5e-12 47.1 0.7 3.3e-12 46.0 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4797) Gamma-thionin PF00304.18 079177.4_18521001_1 - 2.4e-13 50.0 13.9 3.3e-13 49.5 13.9 1.1 1 0 0 1 1 1 1 Gamma-thionin family Toxin_3 PF00537.16 079177.4_18521001_1 - 0.00019 21.4 12.0 0.00026 21.0 12.0 1.2 1 0 0 1 1 1 1 Scorpion toxin-like domain Defensin_2 PF01097.16 079177.4_18521001_1 - 0.89 9.4 7.6 0.31 10.9 4.1 1.9 1 1 1 2 2 2 0 Arthropod defensin YTH PF04146.13 139554.4_18527001_2 - 2.4e-39 133.7 0.0 3.5e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain AAA_12 PF13087.4 139559.4_18529001_1 - 9.3e-37 126.4 0.0 3.8e-36 124.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.4 139559.4_18529001_1 - 4.2e-26 92.1 0.1 6.9e-14 52.1 0.0 2.8 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.4 139559.4_18529001_1 - 1.3e-09 37.9 0.0 3.2e-08 33.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.4 139559.4_18529001_1 - 5.3e-06 26.7 0.0 6.3e-05 23.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain ResIII PF04851.13 139559.4_18529001_1 - 0.00023 21.1 0.0 0.00084 19.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit S1-like PF14444.4 139559.4_18529001_1 - 0.004 17.1 0.0 0.051 13.5 0.0 2.7 2 0 0 2 2 2 1 S1-like PhoH PF02562.14 139559.4_18529001_1 - 0.0045 16.3 0.0 0.87 8.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.19 139559.4_18529001_1 - 0.0053 16.2 0.0 0.2 11.0 0.0 2.9 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.4 139559.4_18529001_1 - 0.025 14.7 0.0 0.27 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.19 139559.4_18529001_1 - 0.044 13.0 0.1 1.1 8.4 0.0 2.9 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.25 139559.4_18529001_1 - 0.14 12.5 0.7 6.4 7.2 0.0 3.6 3 1 1 4 4 4 0 ABC transporter TMF_TATA_bd PF12325.6 139562.3_18529001_1 - 0.62 10.2 8.4 5.1 7.2 4.1 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MIT_C PF16565.3 139589.3_18526001_3 - 3.1e-49 166.4 0.6 4.4e-49 166.0 0.6 1.2 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.16 139589.3_18526001_3 - 1.2e-12 47.6 0.1 2.1e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Trehalose_recp PF06151.11 079189.4_18524001_2 - 1.8e-172 573.5 19.9 2.2e-172 573.2 19.9 1.0 1 0 0 1 1 1 1 Trehalose receptor 7tm_7 PF08395.10 079189.4_18524001_2 - 6.2e-18 65.0 30.4 7.8e-18 64.7 30.4 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor DUF4131 PF13567.4 079189.4_18524001_2 - 2.5 7.5 7.3 4.3 6.8 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Trehalose_recp PF06151.11 168052.3_18523001_1 - 1.4e-172 573.8 17.1 1.4e-172 573.8 16.3 1.2 1 1 0 1 1 1 1 Trehalose receptor 7tm_7 PF08395.10 168052.3_18523001_1 - 9e-21 74.4 21.2 1.2e-20 74.0 21.2 1.2 1 0 0 1 1 1 1 7tm Chemosensory receptor CH PF00307.29 139603.3_18523001_3 - 1.3e-24 86.4 0.3 2.6e-24 85.3 0.2 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain Calponin PF00402.16 139603.3_18523001_3 - 2.8e-10 39.5 1.5 5.4e-10 38.6 1.5 1.5 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.6 139603.3_18523001_3 - 0.0032 17.1 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.9 139603.3_18523001_3 - 0.0034 17.5 0.8 0.0063 16.7 0.2 1.6 2 0 0 2 2 2 1 CDC24 Calponin MAP7 PF05672.9 168063.2_18529001_1 - 1.8e-20 73.2 75.5 1.8e-20 73.2 75.5 3.7 4 0 0 4 4 4 1 MAP7 (E-MAP-115) family Zip PF02535.20 139648.2_18523001_2 - 0.01 14.9 4.5 0.013 14.6 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.4 139651.2_18524001_1 - 0.001 18.6 0.8 0.001 18.6 0.8 1.7 2 0 0 2 2 2 1 FAM176 family Cytotoxic PF09000.8 139651.2_18524001_1 - 0.0042 17.3 0.2 19 5.6 0.0 4.1 1 1 3 4 4 4 1 Cytotoxic DUF1388 PF07142.10 139651.2_18524001_1 - 0.11 12.3 0.9 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) Neur_chan_memb PF02932.14 139651.2_18524001_1 - 2.4 8.0 4.3 4.8 7.0 4.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.20 139651.2_18524001_1 - 7.5 5.5 8.6 12 4.8 8.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter GYR PF02756.12 139653.3_18523001_3 - 3.8e-20 71.1 50.8 9.6e-07 28.3 12.4 3.2 3 0 0 3 3 3 3 GYR motif YLP PF02757.15 139653.3_18523001_3 - 1.2e-08 33.7 19.1 0.027 14.2 0.2 6.5 4 0 0 4 4 4 4 YLP motif Mucin-like PF16058.3 139653.3_18523001_3 - 0.0097 15.8 116.3 25 4.9 14.7 6.7 3 2 0 3 3 3 1 Mucin-like DUF3677 PF12432.6 001104049.4_18529001_1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Comm PF15957.3 001104049.4_18529001_1 - 0.13 12.5 0.6 0.26 11.5 0.6 1.5 1 0 0 1 1 1 0 Commissureless RhoGEF PF00621.18 001104049.4_18529001_2 - 5.1e-43 147.3 5.3 5.1e-43 147.3 5.3 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.27 001104049.4_18529001_2 - 1.1e-17 64.3 1.9 1.6e-12 47.8 0.0 3.3 3 0 0 3 3 3 2 PH domain RBD PF02196.13 001104049.4_18529001_2 - 5.9e-15 55.0 0.1 8.9e-14 51.2 0.0 2.6 2 0 0 2 2 2 1 Raf-like Ras-binding domain PH_9 PF15410.4 001104049.4_18529001_2 - 3.1e-09 37.1 0.4 2.2e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain WH1 PF00568.21 001104049.4_18529001_2 - 0.00068 19.4 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 WH1 domain PDZ PF00595.22 001104049.4_18529001_2 - 0.0057 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SUIM_assoc PF16619.3 001104049.4_18529001_2 - 2 8.5 16.0 31 4.6 0.2 3.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UCH PF00443.27 139729.3_18529001_3 - 5.2e-45 153.8 0.3 5.2e-45 153.8 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 139729.3_18529001_3 - 1.9e-18 67.0 0.4 1.9e-18 67.0 0.4 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF4728 PF15860.3 001104052.2_18524001_2 - 2.9e-23 82.1 8.8 2.9e-23 82.1 8.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4728) EMP24_GP25L PF01105.22 168155.3_18523001_1 - 6.6e-32 110.8 0.2 8.1e-32 110.5 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Chitin_bind_4 PF00379.21 057934.3_18522001_1 - 1e-18 67.4 0.8 1.7e-18 66.7 0.8 1.4 1 0 0 1 1 1 1 Insect cuticle protein Bestrophin PF01062.19 168162.2_18528001_2 - 8.7e-103 343.6 4.1 1.3e-102 343.0 4.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PH PF00169.27 079229.4_18529001_1 - 8.7e-05 22.9 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Ig_3 PF13927.4 168194.4_18529001_2 - 4.3e-105 344.3 7.4 3.5e-12 46.6 0.0 11.8 11 0 0 11 11 10 9 Immunoglobulin domain I-set PF07679.14 168194.4_18529001_2 - 1.2e-103 339.3 0.0 1.1e-16 60.6 0.0 10.4 10 0 0 10 10 10 9 Immunoglobulin I-set domain Ig_2 PF13895.4 168194.4_18529001_2 - 2.5e-81 267.9 0.1 2.2e-08 34.2 0.0 11.1 9 1 1 10 10 10 9 Immunoglobulin domain fn3 PF00041.19 168194.4_18529001_2 - 1.3e-75 249.7 5.4 5.5e-14 52.2 0.9 7.8 7 0 0 7 7 7 6 Fibronectin type III domain ig PF00047.23 168194.4_18529001_2 - 3.5e-57 190.4 10.6 2.4e-09 37.1 0.0 12.0 12 0 0 12 12 11 9 Immunoglobulin domain V-set PF07686.15 168194.4_18529001_2 - 3.6e-31 107.4 21.3 1.1e-05 25.4 0.1 14.6 11 4 2 13 13 12 7 Immunoglobulin V-set domain C2-set_2 PF08205.10 168194.4_18529001_2 - 3.1e-17 62.3 6.2 0.05 13.5 0.0 9.7 9 0 0 9 9 9 5 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 168194.4_18529001_2 - 2.4e-13 50.2 0.0 0.013 15.7 0.0 9.1 10 1 0 10 10 9 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 168194.4_18529001_2 - 3.7e-07 30.5 19.7 0.011 16.2 0.0 8.3 9 1 0 9 9 8 2 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.3 168194.4_18529001_2 - 2e-06 27.7 0.1 0.0034 17.4 0.0 4.0 4 0 0 4 4 4 1 Fibronectin type III domain Izumo-Ig PF16706.3 168194.4_18529001_2 - 5.1e-05 23.1 0.0 43 4.1 0.0 7.2 8 0 0 8 8 8 0 Izumo-like Immunoglobulin domain Macoilin PF09726.7 168194.4_18529001_3 - 1.7 7.0 15.6 3.1 6.1 15.6 1.3 1 0 0 1 1 1 0 Transmembrane protein DM4_12 PF07841.11 139832.3_18523001_3 - 7.2e-15 55.3 0.0 1.3e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 DM4/DM12 family Peptidase_M14 PF00246.22 139862.3_18523001_2 - 1.9e-83 280.5 0.0 2.4e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.14 139862.3_18523001_2 - 1.7e-05 25.0 0.0 4.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF3538 PF12057.6 168217.4_18529001_2 - 3.5e-45 152.3 0.0 9.3e-45 150.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3538) ubiquitin PF00240.21 168217.4_18529001_2 - 2.9e-17 62.0 0.2 5.3e-17 61.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 168217.4_18529001_2 - 7.3e-06 25.6 1.8 1.4e-05 24.7 1.8 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.4 168217.4_18529001_2 - 0.00016 21.6 0.1 0.0004 20.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 168217.4_18529001_2 - 0.067 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.7 168217.4_18529001_2 - 0.074 13.5 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain bZIP_2 PF07716.13 168234.3_18528001_2 - 7.3e-18 64.3 15.1 7.3e-18 64.3 15.1 3.0 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.19 168234.3_18528001_2 - 1.8e-05 24.6 11.9 8.8e-05 22.4 11.9 2.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.15 168234.3_18528001_2 - 0.00075 19.8 8.0 0.00075 19.8 8.0 2.9 3 0 0 3 3 3 1 bZIP Maf transcription factor CCDC92 PF14916.4 168234.3_18528001_2 - 0.014 15.1 0.2 0.032 13.9 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function NYD-SP28_assoc PF14775.4 168234.3_18528001_2 - 0.061 13.3 1.3 0.17 11.9 1.3 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain DivIC PF04977.13 168234.3_18528001_2 - 9.8 5.9 10.1 0.37 10.5 2.8 2.5 2 0 0 2 2 2 0 Septum formation initiator IMUP PF15761.3 168240.2_18525001_2 - 0.0023 18.5 0.3 0.011 16.3 0.3 2.1 1 0 0 1 1 1 1 Immortalisation up-regulated protein Spt20 PF12090.6 168240.2_18525001_2 - 0.043 13.3 10.6 0.092 12.2 10.6 1.5 1 0 0 1 1 1 0 Spt20 family CBM_14 PF01607.22 001104076.2_18523001_3 - 4e-14 52.4 6.4 1e-13 51.1 6.4 1.7 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF3099 PF11298.6 001104076.2_18523001_3 - 0.053 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) TFIIA PF03153.11 001104076.2_18523001_3 - 0.15 11.9 37.2 0.035 14.0 30.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AC_N PF16214.3 001104076.2_18523001_3 - 3.6 6.5 9.8 5.6 5.9 9.8 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DM4_12 PF07841.11 139943.2_18524001_1 - 1.5e-16 60.7 0.0 2.8e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 DM4/DM12 family PDZ PF00595.22 168284.3_18524001_3 - 2.5e-11 43.7 0.0 4.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF4749 PF15936.3 168284.3_18524001_3 - 3.1e-11 44.1 4.4 1.9e-10 41.7 4.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ_2 PF13180.4 168284.3_18524001_3 - 5.9e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain CBM_14 PF01607.22 140004.2_18522001_1 - 0.00084 19.3 4.8 0.00084 19.3 4.8 3.8 4 0 0 4 4 4 1 Chitin binding Peritrophin-A domain CBM_14 PF01607.22 001169922.3_18529001_2 - 1.6e-111 364.2 129.7 2.3e-12 46.7 4.6 17.1 17 0 0 17 17 17 15 Chitin binding Peritrophin-A domain Trypsin PF00089.24 001169922.3_18529001_2 - 2.2e-63 213.9 0.3 4.4e-63 212.9 0.3 1.6 1 0 0 1 1 1 1 Trypsin SRCR PF00530.16 001169922.3_18529001_2 - 1.6e-54 182.4 17.3 3.4e-27 94.7 1.0 4.8 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.4 001169922.3_18529001_2 - 8.5e-08 32.5 6.1 0.0029 18.0 0.6 3.4 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.16 001169922.3_18529001_2 - 9.7e-08 32.0 28.6 1.1e-06 28.5 7.7 5.2 5 0 0 5 5 5 2 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.4 001169922.3_18529001_2 - 8.8e-05 23.3 0.0 0.0002 22.1 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001169922.3_18529001_2 - 0.0014 18.9 0.0 0.0036 17.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.13 001169922.3_18529001_2 - 0.0021 17.6 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 Hepsin-SRCR PF09272.8 001169922.3_18529001_2 - 0.0071 16.5 0.4 8.3 6.6 0.0 3.7 3 0 0 3 3 3 1 Hepsin, SRCR Amidase_2 PF01510.23 206307.2_18524001_3 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase DUF3043 PF11241.6 206307.2_18524001_3 - 0.14 12.1 0.3 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) UDPGP PF01704.16 168325.4_18525001_1 - 1.2e-191 636.7 0.2 1.4e-191 636.5 0.2 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NUDIX_2 PF13869.4 140051.3_18525001_2 - 4.8e-59 199.0 0.0 7.3e-59 198.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX_2 PF13869.4 140051.3_18525001_3 - 4.8e-11 42.4 0.1 7.4e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase DUF2505 PF10698.7 001031947.3_18522001_2 - 0.084 12.8 10.0 0.41 10.6 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2505) Gly-zipper_OmpA PF13436.4 001031947.3_18522001_2 - 0.2 11.4 16.7 0.26 11.0 5.2 3.6 2 2 1 3 3 3 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.4 001031947.3_18522001_2 - 4.1 7.1 26.3 2.8 7.6 10.2 4.3 2 2 2 4 4 4 0 YMGG-like Gly-zipper CarS-like PF01864.15 001031947.3_18522001_2 - 7.8 6.3 9.1 14 5.5 1.2 3.0 1 1 2 3 3 3 0 CDP-archaeol synthase PT PF04886.10 001031947.3_18522001_3 - 2.4e-11 42.8 31.9 0.00032 20.0 11.8 4.4 3 1 1 4 4 4 3 PT repeat Apt1 PF10351.7 176309.3_18527001_2 - 4.6 5.9 13.6 10 4.7 13.6 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_55A PF09788.7 168389.2_18524001_3 - 2.3e-103 344.4 15.1 4.6e-103 343.5 15.1 1.4 1 0 0 1 1 1 1 Transmembrane protein 55A zinc_ribbon_12 PF11331.6 168389.2_18524001_3 - 0.037 13.7 0.6 0.037 13.7 0.6 3.7 3 2 1 4 4 4 0 Probable zinc-ribbon domain TMEM100 PF16311.3 168389.2_18524001_3 - 0.28 10.6 2.2 0.51 9.8 2.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 IBR PF01485.19 168389.2_18524001_3 - 2.4 8.3 24.5 50 4.1 14.1 3.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Pkinase PF00069.23 001104100.2_18529001_1 - 3.6e-15 55.9 0.1 2.4e-14 53.2 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001104100.2_18529001_1 - 2e-12 46.8 0.0 3.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AAA PF00004.27 001104100.2_18529001_1 - 0.051 13.9 0.2 0.16 12.3 0.2 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaJ PF00226.29 140218.4_18522001_3 - 6e-06 26.2 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.11 140218.4_18522001_3 - 0.0033 17.3 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 THAP PF05485.10 140238.2_18522001_3 - 2.2e-14 54.0 5.0 4.9e-14 52.9 5.0 1.6 1 0 0 1 1 1 1 THAP domain GrpE PF01025.17 140238.2_18522001_3 - 0.0019 17.7 1.2 0.0032 17.0 1.2 1.3 1 0 0 1 1 1 1 GrpE Med9 PF07544.11 140238.2_18522001_3 - 0.07 13.1 1.6 0.12 12.3 1.6 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 betaPIX_CC PF16523.3 140238.2_18522001_3 - 0.18 11.5 4.3 0.32 10.7 3.7 1.5 1 1 0 1 1 1 0 betaPIX coiled coil Anoctamin PF04547.10 140278.3_18529001_3 - 9.2e-163 541.9 16.1 1.1e-162 541.6 16.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.3 140278.3_18529001_3 - 1.1e-61 208.4 0.5 1.9e-61 207.5 0.5 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin MIOX PF05153.13 140299.3_18524001_2 - 4.8e-122 406.2 0.8 5.9e-122 405.9 0.8 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.20 140299.3_18524001_2 - 0.2 11.8 0.6 1.7 8.8 0.1 2.1 2 0 0 2 2 2 0 HD domain GRAM PF02893.18 140350.5_18524001_1 - 1.5e-15 56.9 0.0 2.3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.6 140350.5_18524001_1 - 0.0025 17.8 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 BTB PF00651.29 001104129.2_18526001_2 - 3.2e-20 72.3 0.0 6.2e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain GAGA PF09237.9 001104129.2_18526001_2 - 8.3e-05 22.2 3.2 0.02 14.6 0.1 2.6 1 1 1 2 2 2 2 GAGA factor zf-C2H2_4 PF13894.4 001104129.2_18526001_2 - 0.0036 17.9 10.1 0.6 11.0 1.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.24 001104129.2_18526001_2 - 0.015 15.6 2.1 0.015 15.6 2.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Patatin PF01734.20 001104129.2_18526001_2 - 0.079 13.0 0.1 0.3 11.1 0.1 2.0 1 1 0 1 1 1 0 Patatin-like phospholipase zf-C2H2_6 PF13912.4 001104129.2_18526001_2 - 0.26 11.1 7.3 5.1 7.0 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.13 001104129.2_18526001_2 - 4.8 7.2 8.8 1.2 9.1 2.8 2.5 1 1 1 2 2 2 0 BED zinc finger CBM_14 PF01607.22 140391.4_18522001_3 - 1.4e-36 124.3 43.8 4.8e-10 39.3 7.4 4.3 4 0 0 4 4 4 4 Chitin binding Peritrophin-A domain VWD PF00094.23 079336.3_18529001_2 - 9.3e-117 386.6 8.9 6.5e-28 97.9 0.0 6.1 6 0 0 6 6 6 5 von Willebrand factor type D domain C8 PF08742.9 079336.3_18529001_2 - 4.3e-50 167.9 76.0 1.5e-17 63.6 12.8 13.0 11 2 2 13 13 13 5 C8 domain F5_F8_type_C PF00754.23 079336.3_18529001_2 - 2e-35 121.6 0.0 2.1e-16 60.1 0.0 2.7 2 0 0 2 2 2 2 F5/8 type C domain TIL PF01826.15 079336.3_18529001_2 - 4.6e-24 84.3 122.4 2.2e-10 40.5 16.6 25.9 24 3 3 28 28 28 9 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.11 079336.3_18529001_2 - 0.00068 19.2 14.6 0.00068 19.2 14.6 14.1 13 1 1 14 14 14 4 Pacifastin inhibitor (LCMII) EGF_2 PF07974.11 079336.3_18529001_2 - 0.0022 18.2 12.2 0.0022 18.2 12.2 20.4 22 2 2 24 24 24 2 EGF-like domain DUF4826 PF16108.3 079336.3_18529001_3 - 0.071 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4826) COMM_domain PF07258.12 001038923.3_18522001_3 - 6.3e-06 26.1 0.1 1.4e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 COMM domain CBM_14 PF01607.22 001038931.2_18522001_2 - 2.1e-27 94.9 33.5 1.3e-11 44.4 6.2 3.2 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Cullin_binding PF03556.13 140520.4_18524001_1 - 6.4e-37 126.5 0.8 1.1e-36 125.7 0.8 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.4 140520.4_18524001_1 - 2.6e-08 33.4 0.2 6.3e-08 32.2 0.1 1.7 2 0 0 2 2 2 1 UBA-like domain SPRY PF00622.26 140562.2_18523001_2 - 4.8e-15 55.6 0.1 8.1e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 SPRY domain Arf PF00025.19 079374.4_18522001_2 - 7.3e-74 246.8 0.1 8.8e-74 246.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.11 079374.4_18522001_2 - 6.6e-14 52.0 0.0 9.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 079374.4_18522001_2 - 1.5e-12 47.3 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.18 079374.4_18522001_2 - 1.7e-10 40.5 0.3 1.1e-06 27.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.8 079374.4_18522001_2 - 1.1e-09 37.8 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 079374.4_18522001_2 - 3.3e-08 33.0 0.0 4.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 079374.4_18522001_2 - 0.00026 20.9 0.0 0.00042 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 079374.4_18522001_2 - 0.0051 16.2 0.2 0.027 13.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.14 079374.4_18522001_2 - 0.0097 14.8 0.4 0.21 10.4 0.0 2.3 2 1 0 2 2 2 1 ArgK protein AAA_18 PF13238.4 079374.4_18522001_2 - 0.039 14.3 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.25 079374.4_18522001_2 - 0.095 13.1 0.1 0.23 11.9 0.1 1.7 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.7 079374.4_18522001_2 - 0.11 12.2 0.1 7.5 6.2 0.1 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.16 079374.4_18522001_2 - 0.16 11.4 0.7 0.71 9.3 0.7 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B NIF PF03031.16 140568.3_18528001_3 - 4.1e-51 172.7 0.2 6.2e-51 172.1 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_8 PF13855.4 140598.3_18524001_1 - 8.2e-40 134.3 42.6 1.3e-14 53.5 3.8 7.8 3 2 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.5 140598.3_18524001_1 - 2.6e-19 68.8 49.4 0.00017 21.7 1.6 9.1 7 2 1 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 140598.3_18524001_1 - 1.2e-16 60.7 20.8 2.1e-08 34.1 1.0 4.1 1 1 3 5 5 5 4 Leucine rich repeats (6 copies) LRR_6 PF13516.4 140598.3_18524001_1 - 1.9e-10 39.8 22.1 0.85 9.7 0.1 10.3 10 0 0 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.4 140598.3_18524001_1 - 2.8e-07 30.1 16.8 0.027 13.8 1.1 5.0 1 1 4 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.31 140598.3_18524001_1 - 0.0096 16.1 42.1 3.7 8.2 0.1 11.6 12 2 0 12 12 12 3 Leucine Rich Repeat DUF1647 PF07801.9 140598.3_18524001_1 - 0.12 12.1 8.5 0.69 9.6 0.9 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1647) ASH PF15780.3 140649.4_18528001_1 - 0.00016 21.7 0.0 0.022 14.8 0.0 3.0 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.24 140649.4_18528001_1 - 0.067 12.9 0.0 4.7 7.0 0.0 3.1 3 0 0 3 3 3 0 MSP (Major sperm protein) domain DUF4774 PF15999.3 168696.4_18524001_2 - 7.9e-15 54.2 10.6 1.6e-14 53.2 10.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4774) Lig_chan PF00060.24 140755.3_18524001_1 - 6.6e-08 32.4 0.4 1.1e-07 31.7 0.4 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel GON PF08685.9 140757.2_18523001_2 - 0.066 13.0 0.4 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 GON domain P12 PF12669.5 140757.2_18523001_2 - 1.8 8.9 9.4 0.67 10.3 1.3 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family Hydrolase_6 PF13344.4 140757.2_18523001_3 - 1e-22 80.0 0.0 1.8e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.4 140757.2_18523001_3 - 2.8e-11 43.2 0.0 8.7e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.24 140757.2_18523001_3 - 4.1e-06 27.1 0.0 2.1e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.4 140757.2_18523001_3 - 0.022 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GIIM PF08388.9 140757.2_18523001_3 - 0.032 14.2 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Laminin_EGF PF00053.22 001038941.3_18527001_1 - 0.7 10.0 8.6 0.28 11.2 2.7 2.5 2 0 0 2 2 2 0 Laminin EGF domain P4Ha_N PF08336.9 001038941.3_18527001_3 - 1.7e-24 86.2 2.6 2.7e-24 85.5 2.6 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_8 PF13181.4 001038941.3_18527001_3 - 0.00013 21.8 2.4 0.3 11.3 0.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.15 001038941.3_18527001_3 - 0.00064 19.5 4.4 0.076 13.0 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.4 001038941.3_18527001_3 - 0.012 16.4 0.0 0.023 15.5 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ribosomal_L21p PF00829.19 140838.3_18522001_2 - 2.3e-27 95.1 0.0 3.4e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF4495 PF14906.4 140844.3_18526001_3 - 6.1e-120 399.9 5.2 1.1e-119 399.2 5.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4495) TMEM72 PF16054.3 140845.4_18524001_2 - 1.4e-28 99.7 2.5 2.1e-28 99.2 2.5 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 COPI_assoc PF08507.8 140845.4_18524001_2 - 0.088 12.8 4.6 2.4 8.1 0.3 2.3 2 0 0 2 2 2 0 COPI associated protein DUF308 PF03729.11 140845.4_18524001_2 - 0.64 10.2 6.8 0.045 14.0 1.7 1.7 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) AdoMetDC_leader PF08132.9 140857.3_18522001_2 - 4.2 7.3 6.0 16 5.4 0.8 2.9 2 1 0 2 2 2 0 S-adenosyl-l-methionine decarboxylase leader peptide His_Phos_2 PF00328.20 001275120.2_18523001_2 - 3.4e-24 85.8 0.1 1.5e-21 77.1 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lon_C PF05362.11 168806.3_18528001_1 - 2e-73 246.2 0.1 4.4e-73 245.0 0.1 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.14 168806.3_18528001_1 - 2.2e-37 128.8 1.9 4.9e-37 127.7 1.9 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.27 168806.3_18528001_1 - 5.8e-23 81.6 0.0 1.2e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.12 168806.3_18528001_1 - 9.5e-10 38.5 0.0 1.5e-07 31.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.4 168806.3_18528001_1 - 3.5e-07 29.9 0.0 7.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.12 168806.3_18528001_1 - 5.9e-07 29.6 0.0 1.7e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.4 168806.3_18528001_1 - 6.6e-06 26.5 0.3 2.3e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.9 168806.3_18528001_1 - 1e-05 24.5 0.0 1.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.10 168806.3_18528001_1 - 2.4e-05 23.6 0.0 0.00025 20.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.4 168806.3_18528001_1 - 0.00039 20.6 0.4 0.006 16.7 0.0 2.8 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.20 168806.3_18528001_1 - 0.0024 18.1 0.0 0.0077 16.5 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.4 168806.3_18528001_1 - 0.0029 17.5 0.0 0.0096 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.20 168806.3_18528001_1 - 0.017 14.0 0.0 0.038 12.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_3 PF07726.9 168806.3_18528001_1 - 0.018 14.8 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.15 168806.3_18528001_1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.4 168806.3_18528001_1 - 0.027 14.8 0.0 0.076 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.14 168806.3_18528001_1 - 0.039 13.7 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.4 168806.3_18528001_1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.10 168806.3_18528001_1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.15 168806.3_18528001_1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.4 168806.3_18528001_1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.9 168806.3_18528001_1 - 0.11 12.4 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 Torsin ClpB_D2-small PF10431.7 168806.3_18528001_1 - 0.14 12.1 2.9 0.81 9.7 0.0 3.2 2 1 2 4 4 4 0 C-terminal, D2-small domain, of ClpB protein ABC_tran PF00005.25 168806.3_18528001_1 - 0.25 11.7 1.6 0.64 10.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.4 168806.3_18528001_1 - 0.61 10.4 12.3 1 9.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain WWE PF02825.18 001144508.3_18523001_3 - 5.1e-09 36.4 0.4 1.9e-05 25.0 0.6 2.3 2 0 0 2 2 2 2 WWE domain zf-C3HC4_3 PF13920.4 001144508.3_18523001_3 - 2.4e-07 30.4 11.3 2.4e-07 30.4 11.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001144508.3_18523001_3 - 6.2e-06 26.2 12.6 1.5e-05 25.0 12.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.4 001144508.3_18523001_3 - 1.4e-05 24.8 11.0 3.4e-05 23.6 11.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001144508.3_18523001_3 - 6.2e-05 22.6 12.9 0.00014 21.5 12.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.4 001144508.3_18523001_3 - 0.00015 21.8 11.6 0.00032 20.6 11.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.4 001144508.3_18523001_3 - 0.00025 20.7 9.9 0.0015 18.3 10.3 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 001144508.3_18523001_3 - 0.0058 16.4 12.1 0.014 15.2 12.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.4 001144508.3_18523001_3 - 0.017 14.8 12.9 0.032 13.9 12.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Med12-LCEWAV PF12145.6 080047.2_18529001_3 - 1.6e-173 577.8 0.2 1.6e-173 577.8 0.2 3.7 2 2 1 3 3 3 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.8 080047.2_18529001_3 - 9e-15 54.6 0.1 2.8e-14 53.0 0.1 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 ELL PF10390.7 140898.5_18529001_1 - 1.7e-115 385.1 12.8 1.7e-115 385.1 12.8 4.5 4 1 0 4 4 4 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.11 140898.5_18529001_1 - 3.6e-28 98.1 4.7 3.6e-28 98.1 4.7 3.6 3 0 0 3 3 3 1 Occludin homology domain Cadherin PF00028.15 001031967.2_18529001_1 - 0 1587.8 87.7 2.3e-21 75.9 0.0 34.6 34 0 0 34 34 34 34 Cadherin domain Cadherin_2 PF08266.10 001031967.2_18529001_1 - 3.2e-33 113.3 7.2 0.53 10.0 0.0 21.9 23 0 0 23 23 23 7 Cadherin-like Laminin_G_2 PF02210.22 001031967.2_18529001_1 - 1.8e-24 86.6 0.0 1.5e-23 83.6 0.0 2.8 2 0 0 2 2 1 1 Laminin G domain Cadherin_3 PF16184.3 001031967.2_18529001_1 - 4.2e-22 78.1 79.7 0.12 12.3 0.2 24.4 23 2 2 25 25 25 8 Cadherin-like Laminin_G_1 PF00054.21 001031967.2_18529001_1 - 1.5e-16 60.6 0.0 6.9e-16 58.5 0.0 2.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.25 001031967.2_18529001_1 - 1.4e-10 41.1 86.5 0.00044 20.3 7.4 7.1 7 0 0 7 7 7 5 EGF-like domain Cadherin_pro PF08758.9 001031967.2_18529001_1 - 7.7e-10 38.7 7.5 3.6 7.7 0.0 12.4 15 0 0 15 15 15 2 Cadherin prodomain like EGF_CA PF07645.13 001031967.2_18529001_1 - 2.5e-05 24.3 7.5 2.5e-05 24.3 7.5 6.0 4 2 1 5 5 4 1 Calcium-binding EGF domain SusE PF14292.4 001031967.2_18529001_1 - 4.2e-05 23.8 14.4 0.05 13.9 0.0 8.8 8 2 1 9 9 7 2 SusE outer membrane protein hEGF PF12661.5 001031967.2_18529001_1 - 0.005 17.3 5.4 0.005 17.3 5.4 7.0 6 0 0 6 6 6 1 Human growth factor-like EGF PAP_PilO PF06864.10 001031967.2_18529001_1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) CBM_14 PF01607.22 140930.5_18523001_2 - 2.4e-28 98.0 62.1 8.7e-08 32.1 6.4 5.4 5 0 0 5 5 5 5 Chitin binding Peritrophin-A domain CBM_14 PF01607.22 140932.3_18523001_2 - 1.3e-38 130.8 53.8 7e-11 42.0 6.9 5.3 5 0 0 5 5 5 5 Chitin binding Peritrophin-A domain Serpin PF00079.18 140949.2_18523001_2 - 7e-42 143.9 0.0 1.2e-41 143.2 0.0 1.2 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) LEM PF03020.13 141014.2_18527001_2 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 LEM domain Peptidase_M16_M PF16187.3 141014.2_18527001_3 - 7.4e-67 225.4 1.5 1.9e-66 224.1 1.5 1.8 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.19 141014.2_18527001_3 - 1e-36 126.5 3.0 3e-17 63.1 0.1 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.18 141014.2_18527001_3 - 1.9e-33 115.4 1.4 8.9e-33 113.2 0.1 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF4729 PF15866.3 168899.1_18525001_2 - 5.8e-32 110.6 0.1 1.1e-31 109.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4729) Pkinase PF00069.23 001275245.3_18529001_2 - 1.2e-54 185.3 0.0 1.2e-54 185.3 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001275245.3_18529001_2 - 3.8e-42 144.2 0.0 3.8e-42 144.2 0.0 3.5 3 1 1 4 4 4 1 Protein tyrosine kinase OSR1_C PF12202.6 001275245.3_18529001_2 - 1.1e-16 60.4 0.7 1.1e-16 60.4 0.7 1.7 2 0 0 2 2 2 1 Oxidative-stress-responsive kinase 1 C terminal SMC_N PF02463.17 206419.3_18527001_2 - 5.8e-20 71.5 0.0 2e-19 69.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.4 206419.3_18527001_2 - 4.1e-08 33.8 36.8 4.1e-08 33.8 36.8 5.6 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.4 206419.3_18527001_2 - 6.4e-08 32.6 0.2 0.00025 20.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.4 206419.3_18527001_2 - 8e-06 25.4 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.4 206419.3_18527001_2 - 0.002 17.7 26.4 0.002 17.7 26.4 3.6 2 2 1 3 3 2 1 AAA ATPase domain ABC_tran PF00005.25 206419.3_18527001_2 - 0.026 14.9 0.4 0.026 14.9 0.4 3.7 2 2 0 3 3 1 0 ABC transporter AAA PF00004.27 206419.3_18527001_2 - 0.077 13.3 0.5 0.53 10.6 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HALZ PF02183.16 206419.3_18527001_2 - 0.098 12.7 14.5 0.8 9.8 5.0 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper AAA_25 PF13481.4 206419.3_18527001_2 - 0.11 11.9 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.4 206419.3_18527001_2 - 0.14 11.6 0.0 0.14 11.6 0.0 4.3 3 1 2 5 5 5 0 AAA domain RNA_helicase PF00910.20 206419.3_18527001_2 - 0.54 10.5 7.8 2.1 8.6 0.0 4.2 4 0 0 4 4 4 0 RNA helicase AAA_24 PF13479.4 206419.3_18527001_2 - 5.3 6.6 11.2 1.9 8.0 2.3 3.5 3 1 0 3 3 3 0 AAA domain BTB PF00651.29 206420.2_18529001_3 - 8.4e-19 67.7 1.3 3.9e-18 65.5 0.0 2.6 2 1 1 3 3 3 1 BTB/POZ domain Ank_2 PF12796.5 206420.2_18529001_3 - 1.6e-13 50.9 0.5 2e-08 34.6 0.1 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.4 206420.2_18529001_3 - 1.7e-10 40.8 6.4 0.002 18.3 0.1 5.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.4 206420.2_18529001_3 - 4.4e-08 32.6 6.0 0.37 11.4 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.4 206420.2_18529001_3 - 1.8e-06 28.2 0.2 0.005 17.3 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.28 206420.2_18529001_3 - 6.3e-06 26.3 4.3 0.012 15.9 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat DUF4794 PF16042.3 141098.3_18522001_3 - 1.8e-13 51.1 21.4 1.8e-13 51.1 21.4 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4794) PDZ PF00595.22 168937.3_18527001_3 - 8.1e-18 64.4 0.4 1.6e-17 63.5 0.4 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PH PF00169.27 168937.3_18527001_3 - 6.8e-05 23.2 0.0 0.49 10.8 0.0 2.5 2 0 0 2 2 2 2 PH domain PDZ_2 PF13180.4 168937.3_18527001_3 - 0.002 18.3 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GRP PF07172.9 168937.3_18527001_3 - 1.1 9.9 20.1 0.54 10.9 11.1 2.4 2 0 0 2 2 2 0 Glycine rich protein family Ssl1 PF04056.12 141170.3_18524001_2 - 1.9e-89 298.4 0.8 2.3e-89 298.2 0.2 1.4 2 0 0 2 2 2 1 Ssl1-like C1_4 PF07975.10 141170.3_18524001_2 - 1.3e-18 66.8 12.7 1.3e-18 66.8 12.7 3.1 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.4 141170.3_18524001_2 - 3.5e-12 46.8 0.0 7.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.26 141170.3_18524001_2 - 5.3e-05 23.4 0.0 9.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.19 141170.3_18524001_2 - 0.0072 16.4 1.8 0.0072 16.4 1.8 2.8 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain Piwi PF02171.15 001043163.3_18526001_2 - 3e-87 292.5 3.2 2.1e-86 289.7 2.3 2.2 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.20 001043163.3_18526001_2 - 7.1e-28 97.0 2.3 7.1e-28 97.0 2.3 1.8 2 0 0 2 2 2 1 PAZ domain ArgoL1 PF08699.8 001043163.3_18526001_2 - 0.0013 18.2 0.0 0.0032 16.9 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain GAIN PF16489.3 001043163.3_18526001_2 - 0.047 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain ERAP1_C PF11838.6 001043170.2_18526001_1 - 5.3e-55 187.1 0.0 7.3e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.18 001043170.2_18526001_1 - 5.6e-46 157.4 0.0 8.4e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Op_neuropeptide PF08035.9 001043170.2_18526001_1 - 0.083 12.6 1.0 0.22 11.3 0.1 2.2 2 0 0 2 2 2 0 Opioids neuropeptide Peptidase_M1 PF01433.18 167884.2_18528001_3 - 6.8e-143 476.5 0.0 9.5e-143 476.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.6 167884.2_18528001_3 - 4e-92 309.0 0.4 8.5e-92 307.9 0.1 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain CTP_transf_like PF01467.24 167893.2_18525001_1 - 1.2e-24 87.0 0.0 2.9e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase-like LIM PF00412.20 168042.2_18525001_3 - 2e-24 85.4 33.2 4.7e-14 52.2 4.5 2.9 3 0 0 3 3 3 2 LIM domain Homeobox PF00046.27 168042.2_18525001_3 - 1.1e-18 66.7 1.0 2.7e-18 65.4 1.0 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 168042.2_18525001_3 - 0.014 15.1 0.0 0.045 13.5 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain GIDE PF12483.6 001316436.1_18524001_1 - 4.4e-35 120.5 0.1 7.6e-35 119.7 0.1 1.4 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.4 001316436.1_18524001_1 - 4.6e-14 51.9 11.6 1.1e-13 50.7 11.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001316436.1_18524001_1 - 6.6e-09 35.4 11.3 1.2e-08 34.5 11.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 001316436.1_18524001_1 - 0.00057 19.7 11.2 0.00057 19.7 11.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.4 001316436.1_18524001_1 - 0.0014 18.7 13.3 0.0033 17.5 13.3 1.7 1 0 0 1 1 1 1 Ring finger domain Miga PF10265.7 001316436.1_18524001_1 - 0.087 11.6 0.4 0.13 11.0 0.4 1.2 1 0 0 1 1 1 0 Mitoguardin Vpu PF00558.17 001316436.1_18524001_1 - 0.18 11.4 0.4 0.45 10.2 0.4 1.6 1 0 0 1 1 1 0 Vpu protein Drc1-Sld2 PF11719.6 167951.2_18524001_3 - 0.017 14.6 3.4 0.026 14.0 3.0 1.4 1 1 0 1 1 1 0 DNA replication and checkpoint protein Pkinase PF00069.23 167791.3_18529001_2 - 5.3e-55 186.5 2.2 1.7e-34 119.3 0.1 2.5 3 0 0 3 3 3 2 Protein kinase domain PH_3 PF14593.4 167791.3_18529001_2 - 2.7e-41 139.8 0.0 5.5e-41 138.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.15 167791.3_18529001_2 - 6.3e-26 91.1 0.0 2.5e-19 69.5 0.2 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.12 167791.3_18529001_2 - 0.0018 17.6 0.3 0.0039 16.4 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pex14_N PF04695.11 167791.3_18529001_2 - 0.002 18.7 7.4 0.002 18.7 7.4 3.0 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RIO1 PF01163.20 167791.3_18529001_2 - 0.0046 16.4 1.8 0.01 15.3 0.4 2.1 1 1 1 2 2 2 1 RIO1 family APH PF01636.21 167791.3_18529001_2 - 0.012 15.5 0.2 0.012 15.5 0.2 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Activator_LAG-3 PF11498.6 167791.3_18529001_2 - 2.5 6.9 33.9 5.2 5.8 33.9 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HSP90 PF00183.16 001274433.1_18526001_1 - 5.9e-235 780.8 27.8 7.6e-235 780.5 27.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.24 001274433.1_18526001_1 - 1.8e-14 54.1 0.0 3.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001274433.1_18526001_1 - 2.5e-10 40.2 0.2 7.3e-10 38.7 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIE_beta PF02186.13 001169875.1_18523001_2 - 1.5e-19 69.9 0.0 4.6e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 TFIIE beta subunit core domain Trypsin PF00089.24 001274477.1_18524001_3 - 4.4e-58 196.6 0.0 6.9e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin CLIP PF12032.6 001274477.1_18524001_3 - 4.5e-10 39.5 5.3 1.1e-09 38.3 5.3 1.7 1 0 0 1 1 1 1 Regulatory CLIP domain of proteinases DUF1986 PF09342.9 001274477.1_18524001_3 - 0.00058 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001274477.1_18524001_3 - 0.0028 18.4 0.0 0.0068 17.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.13 001274477.1_18524001_3 - 0.0042 16.6 0.0 0.023 14.1 0.0 2.0 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 Chitin_bind_4 PF00379.21 001274364.1_18523001_3 - 4.6e-15 55.8 5.2 4.6e-15 55.8 5.2 1.9 2 0 0 2 2 2 1 Insect cuticle protein R3H PF01424.20 139503.3_18526001_3 - 1.6e-12 47.1 0.0 3.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain NCBP3 PF10309.7 139503.3_18526001_3 - 0.0003 20.4 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.9 139503.3_18526001_3 - 0.00056 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain UPF0561 PF10573.7 139503.3_18526001_3 - 0.024 14.6 1.6 0.024 14.6 1.6 3.3 3 1 0 3 3 3 0 Uncharacterised protein family UPF0561 zf-C2H2_4 PF13894.4 001274323.1_18526001_2 - 6.2e-11 42.0 55.2 0.01 16.5 1.8 9.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2 PF00096.24 001274323.1_18526001_2 - 1.3e-08 34.7 53.0 0.0037 17.5 2.7 8.8 9 0 0 9 9 9 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 001274323.1_18526001_2 - 7e-05 22.9 29.7 0.21 11.8 0.5 6.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001274323.1_18526001_2 - 0.0017 18.1 1.3 0.0017 18.1 1.3 7.9 9 0 0 9 9 9 3 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001274323.1_18526001_2 - 0.012 15.7 1.1 0.012 15.7 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc ribbon TEX19 PF15553.4 001274323.1_18526001_2 - 0.43 10.4 3.8 2.7 7.8 0.2 3.3 3 1 1 4 4 4 0 Testis-expressed protein 19 zf-met PF12874.5 001274323.1_18526001_2 - 0.92 9.8 43.2 0.039 14.2 1.3 8.0 9 0 0 9 9 9 0 Zinc-finger of C2H2 type zf-ribbon_3 PF13248.4 001274323.1_18526001_2 - 3.9 6.9 11.0 2.3 7.6 0.0 3.7 4 0 0 4 4 4 0 zinc-ribbon domain LRR_8 PF13855.4 140071.4_18524001_3 - 1.7e-22 78.8 24.3 6.3e-13 48.2 2.5 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 140071.4_18524001_3 - 1.4e-11 44.2 16.1 4.8e-06 26.7 1.3 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 140071.4_18524001_3 - 7e-07 28.7 6.8 0.12 12.8 0.4 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.4 140071.4_18524001_3 - 0.0011 18.7 4.9 4.9 7.3 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.4 140071.4_18524001_3 - 0.0017 17.7 0.9 0.0031 16.9 0.3 1.6 2 0 0 2 2 2 1 Leucine-rich repeat K_channel_TID PF07941.9 140071.4_18524001_3 - 5.3 7.4 7.2 0.61 10.4 2.2 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ECH_1 PF00378.18 001275198.1_18527001_3 - 3.4e-19 69.0 0.0 5.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase zf-H2C2_2 PF13465.4 168343.2_18527001_3 - 1.4e-24 85.3 37.1 1.5e-08 34.5 0.6 6.7 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.24 168343.2_18527001_3 - 7.2e-21 73.3 46.7 2.3e-05 24.5 3.3 6.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 168343.2_18527001_3 - 4.4e-06 26.9 62.2 0.001 19.5 3.6 7.0 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 168343.2_18527001_3 - 0.29 11.4 30.3 0.26 11.5 2.7 5.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 168343.2_18527001_3 - 0.57 10.1 34.2 0.044 13.6 2.4 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.5 168343.2_18527001_3 - 4.8 7.6 26.0 0.022 15.0 3.4 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type UDPGT PF00201.16 140828.3_18526001_3 - 8.8e-42 143.4 0.0 1.2e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 140828.3_18526001_3 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain EphA2_TM PF14575.4 140828.3_18526001_3 - 0.13 13.0 0.1 20 6.0 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UDPGT PF00201.16 001300182.1_18527001_3 - 1.2e-41 143.0 0.0 1.7e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001300182.1_18527001_3 - 0.02 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain EphA2_TM PF14575.4 001300182.1_18527001_3 - 0.18 12.5 0.1 23 5.7 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Endonuclease_NS PF01223.21 140821.5_18523001_2 - 5.9e-47 160.2 0.1 7.8e-47 159.8 0.1 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease AMP-binding PF00501.26 168781.3_18527001_2 - 1.7e-108 362.8 0.0 2.3e-108 362.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 168781.3_18527001_2 - 2.2e-05 25.2 0.0 4.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_16 PF05301.9 170631.1_18525001_2 - 1.5e-66 223.3 0.0 2.5e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 TonB_N PF16031.3 170631.1_18525001_2 - 0.00047 20.5 16.4 0.00077 19.8 16.4 1.3 1 0 0 1 1 1 1 TonB N-terminal region Trypan_PARP PF05887.9 170631.1_18525001_2 - 0.0025 17.7 19.8 0.0047 16.8 19.8 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Acetyltransf_10 PF13673.5 170631.1_18525001_2 - 0.0052 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 170631.1_18525001_2 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.23 170631.1_18525001_2 - 0.026 14.6 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SPESP1 PF15754.3 170631.1_18525001_2 - 4 6.4 6.6 6.3 5.7 6.6 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 IF4E PF01652.16 168334.1_18523001_3 - 5.3e-56 188.7 0.7 8.1e-56 188.1 0.7 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IF4E PF01652.16 001274697.1_18523001_2 - 5.8e-56 188.5 0.7 8.9e-56 187.9 0.7 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NUFIP1 PF10453.7 140801.4_18524001_3 - 9.4e-16 57.3 2.4 9.4e-16 57.3 2.4 2.6 2 1 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1644 PF07800.10 140801.4_18524001_3 - 8.3 6.3 9.9 0.3 11.0 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) Efg1 PF10153.7 140801.4_18524001_3 - 9.2 6.5 10.6 23 5.2 10.6 1.7 1 0 0 1 1 1 0 rRNA-processing protein Efg1 Glyco_hydro_16 PF00722.19 168772.2_18523001_2 - 5.5e-08 32.4 0.2 1.7e-05 24.2 0.2 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 CBM39 PF15886.3 168772.2_18523001_2 - 4.4e-06 26.5 0.2 2.9e-05 23.9 0.0 2.3 3 0 0 3 3 3 1 Carbohydrate binding domain (family 32) Abhydrolase_1 PF00561.18 001259635.2_18524001_2 - 3.6e-18 66.0 0.2 1.1e-17 64.4 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001259635.2_18524001_2 - 2.1e-10 41.5 0.0 3.4e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001259635.2_18524001_2 - 2.4e-05 23.6 0.0 5.3e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 CBM_14 PF01607.22 001259669.1_18527001_1 - 2e-09 37.4 3.8 3.2e-09 36.7 3.8 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain GTP_EFTU PF00009.25 001259671.2_18528001_2 - 1.1e-35 122.8 3.4 8.9e-35 119.9 0.0 2.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.6 001259671.2_18528001_2 - 1.9e-19 69.6 0.1 5.7e-19 68.0 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.23 001259671.2_18528001_2 - 5.1e-12 45.9 4.8 9.7e-11 41.8 0.2 4.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001259671.2_18528001_2 - 5.3e-08 32.8 0.5 5e-07 29.7 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001259671.2_18528001_2 - 4.4e-06 26.4 0.2 1.9e-05 24.5 0.2 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.11 001259671.2_18528001_2 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.15 001259671.2_18528001_2 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.20 001259671.2_18528001_2 - 0.018 14.5 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 Ras family DCA16 PF15349.4 001259671.2_18528001_2 - 0.046 13.1 0.0 0.17 11.3 0.0 1.9 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 AAA_22 PF13401.4 001259671.2_18528001_2 - 0.42 10.8 2.8 0.66 10.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain Endostatin PF06482.9 001259722.1_18528001_1 - 4.8e-81 272.1 0.0 1.2e-79 267.5 0.0 2.1 1 1 0 1 1 1 1 Collagenase NC10 and Endostatin Collagen PF01391.16 001259722.1_18528001_1 - 1.6e-34 117.3 164.7 1.5e-09 37.3 28.0 6.8 4 1 2 6 6 6 6 Collagen triple helix repeat (20 copies) Laminin_G_3 PF13385.4 001259722.1_18528001_1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily TFIIA PF03153.11 079413.3_18524001_1 - 0.042 13.7 11.1 0.081 12.8 11.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glypican PF01153.17 001259756.2_18529001_3 - 1.6e-176 588.3 0.1 2.1e-176 587.9 0.1 1.1 1 0 0 1 1 1 1 Glypican SH3_1 PF00018.26 001259761.2_18526001_3 - 2.3e-29 100.6 2.0 3.4e-15 55.3 0.5 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 001259761.2_18526001_3 - 1.5e-24 85.4 4.6 1.4e-11 43.9 0.4 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.15 001259761.2_18526001_3 - 5.6e-19 67.5 0.3 1.5e-09 37.2 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain FCH PF00611.21 001259761.2_18526001_3 - 5e-18 65.0 0.7 5e-18 65.0 0.7 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.9 001259761.2_18526001_3 - 6.9e-05 22.9 0.4 0.00019 21.5 0.4 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain AnfO_nitrog PF09582.8 001259761.2_18526001_3 - 0.041 13.1 0.8 0.099 11.8 0.8 1.6 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) SH3_1 PF00018.26 001259763.2_18529001_3 - 1.5e-28 98.0 2.0 7.8e-15 54.1 0.5 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 001259763.2_18529001_3 - 1.2e-23 82.5 4.6 3.3e-11 42.7 0.4 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.15 001259763.2_18529001_3 - 4.4e-18 64.6 0.2 3.6e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.21 001259763.2_18529001_3 - 1.1e-17 64.0 2.6 1.2e-17 63.7 0.7 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.9 001259763.2_18529001_3 - 0.00017 21.6 0.4 0.00044 20.3 0.4 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AnfO_nitrog PF09582.8 001259763.2_18529001_3 - 0.13 11.4 0.9 0.27 10.4 0.9 1.4 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) HSP20 PF00011.19 001259765.2_18522001_3 - 5.4e-30 103.4 0.1 7.3e-30 103.0 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Guanylate_cyc PF00211.18 001259814.1_18529001_1 - 8.6e-64 214.4 0.0 1.4e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.26 001259814.1_18529001_1 - 7.3e-39 133.7 0.0 1.1e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.15 001259814.1_18529001_1 - 2.9e-38 131.5 0.0 4.6e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001259814.1_18529001_1 - 3.7e-34 118.1 0.0 5.8e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.12 001259814.1_18529001_1 - 1.5e-05 24.4 0.6 2.8e-05 23.6 0.6 1.4 1 0 0 1 1 1 1 Heme NO binding associated 7tm_6 PF02949.18 001259834.2_18523001_1 - 4.2e-45 154.0 14.2 3e-43 147.9 14.2 2.1 1 1 0 1 1 1 1 7tm Odorant receptor Pkr1 PF08636.8 001259834.2_18523001_1 - 0.0074 16.3 0.1 0.037 14.0 0.1 2.2 1 0 0 1 1 1 1 ER protein Pkr1 FAM76 PF16046.3 140046.4_18524001_2 - 1.6e-103 346.1 22.4 1.6e-103 346.1 22.4 1.8 2 0 0 2 2 2 1 FAM76 protein IncA PF04156.12 140046.4_18524001_2 - 0.00021 21.0 1.3 0.00039 20.1 1.3 1.5 1 0 0 1 1 1 1 IncA protein PKcGMP_CC PF16808.3 140046.4_18524001_2 - 0.022 14.4 4.2 0.21 11.3 4.2 2.6 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4094 PF13334.4 140046.4_18524001_2 - 0.13 12.5 3.2 1.1 9.6 3.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Prefoldin PF02996.15 140046.4_18524001_2 - 1.3 8.8 10.2 0.65 9.8 2.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin_2 PF01920.18 140046.4_18524001_2 - 6.9 6.6 15.4 3 7.7 5.3 2.4 1 1 0 2 2 2 0 Prefoldin subunit CC2-LZ PF16516.3 140046.4_18524001_2 - 7.5 6.8 13.9 0.54 10.5 5.2 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MPS2 PF17060.3 140046.4_18524001_2 - 7.9 5.5 11.4 12 4.9 9.1 1.9 1 1 1 2 2 2 0 Monopolar spindle protein 2 Acyltransf_C PF16076.3 001259864.1_18524001_2 - 3.7e-24 84.5 0.0 7.8e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.19 001259864.1_18524001_2 - 6.3e-13 48.4 0.1 2.4e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase zf-C4 PF00105.16 001259893.2_18529001_2 - 5.6e-31 106.7 15.1 1.8e-30 105.0 15.1 2.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001259893.2_18529001_2 - 1e-19 70.8 0.0 2.6e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RIIa PF02197.15 001259893.2_18529001_3 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Trypsin PF00089.24 001259896.2_18523001_3 - 1.4e-59 201.5 0.5 1.7e-59 201.2 0.5 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001259896.2_18523001_3 - 4.8e-05 23.6 0.1 0.00022 21.4 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001259896.2_18523001_3 - 0.00038 21.2 0.0 0.0014 19.4 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Ras PF00071.20 001259908.2_18525001_2 - 2.3e-64 215.8 1.2 3.4e-64 215.2 1.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001259908.2_18525001_2 - 2.9e-33 114.5 0.2 4.9e-33 113.8 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001259908.2_18525001_2 - 2.5e-15 56.2 0.4 3.9e-15 55.6 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001259908.2_18525001_2 - 2.7e-05 23.5 0.2 3.9e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001259908.2_18525001_2 - 0.00014 21.2 0.5 0.00023 20.5 0.5 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001259908.2_18525001_2 - 0.0038 17.2 0.1 0.0075 16.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001259908.2_18525001_2 - 0.036 13.8 0.1 5.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001259908.2_18525001_2 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Lipase PF00151.17 001259915.1_18523001_1 - 3.1e-42 144.9 3.3 9.3e-39 133.5 3.3 2.8 1 1 0 1 1 1 1 Lipase LRR_8 PF13855.4 001259916.2_18526001_3 - 3.6e-40 135.4 21.6 5.7e-11 41.9 0.0 7.2 5 1 2 7 7 7 5 Leucine rich repeat TIR PF01582.18 001259916.2_18526001_3 - 1.7e-18 66.9 0.9 3.2e-18 66.0 0.9 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001259916.2_18526001_3 - 1.5e-15 56.8 24.6 0.00039 20.6 1.5 8.7 3 2 7 11 11 11 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001259916.2_18526001_3 - 8.6e-10 38.5 4.4 0.00081 19.2 0.1 4.2 2 1 1 4 4 4 2 Leucine rich repeats (6 copies) TIR_2 PF13676.4 001259916.2_18526001_3 - 9.5e-08 32.2 0.0 2.2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001259916.2_18526001_3 - 0.00013 21.4 4.8 0.94 8.8 0.4 4.0 2 2 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.31 001259916.2_18526001_3 - 0.00049 20.0 21.0 20 6.0 0.0 10.2 10 2 0 10 10 10 1 Leucine Rich Repeat LRR_6 PF13516.4 001259916.2_18526001_3 - 0.076 13.0 29.7 3.4 7.8 0.2 10.2 11 0 0 11 11 11 0 Leucine Rich repeat KH_1 PF00013.27 001259945.2_18527001_2 - 3e-50 167.8 15.2 3.3e-18 65.1 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.15 001259945.2_18527001_2 - 1.4e-10 40.7 9.3 0.00059 19.5 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.4 001259945.2_18527001_2 - 3.1e-06 26.8 6.5 0.038 13.7 0.2 3.8 4 0 0 4 4 4 3 KH domain KH_5 PF13184.4 001259945.2_18527001_2 - 0.01 15.7 8.7 4.8 7.2 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain MOEP19 PF16005.3 001259945.2_18527001_2 - 0.013 15.4 0.0 0.38 10.7 0.0 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain KH_1 PF00013.27 001259946.2_18527001_2 - 3.4e-50 167.6 15.2 3.4e-18 65.1 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.15 001259946.2_18527001_2 - 1.5e-10 40.7 7.7 0.0016 18.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.4 001259946.2_18527001_2 - 6.6e-06 25.8 7.1 0.039 13.7 0.2 3.8 4 0 0 4 4 4 3 KH domain KH_5 PF13184.4 001259946.2_18527001_2 - 0.012 15.6 8.7 5 7.2 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain MOEP19 PF16005.3 001259946.2_18527001_2 - 0.013 15.3 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain Ig_3 PF13927.4 001259961.2_18529001_3 - 1.3e-49 166.5 29.1 6.3e-11 42.6 0.8 10.2 9 0 0 9 9 9 9 Immunoglobulin domain Ig_2 PF13895.4 001259961.2_18529001_3 - 5.7e-39 132.2 27.9 9.3e-07 29.0 0.2 10.2 11 0 0 11 11 9 8 Immunoglobulin domain I-set PF07679.14 001259961.2_18529001_3 - 7.8e-34 115.5 13.3 5.6e-08 32.6 0.1 9.8 9 1 0 9 9 9 7 Immunoglobulin I-set domain ig PF00047.23 001259961.2_18529001_3 - 1.2e-24 86.1 16.4 0.00013 21.9 0.2 10.0 9 0 0 9 9 9 6 Immunoglobulin domain C2-set_2 PF08205.10 001259961.2_18529001_3 - 2.7e-22 78.5 5.2 2e-10 40.5 0.1 5.6 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain V-set PF07686.15 001259961.2_18529001_3 - 1.7e-18 66.6 9.1 1.8e-06 27.9 0.0 8.7 7 1 0 7 7 7 3 Immunoglobulin V-set domain C1-set PF07654.13 001259961.2_18529001_3 - 4.6e-12 46.1 19.7 1.3e-05 25.4 0.0 8.4 9 0 0 9 9 8 3 Immunoglobulin C1-set domain Receptor_2B4 PF11465.6 001259961.2_18529001_3 - 0.0051 16.9 3.6 0.033 14.3 0.1 3.6 4 0 0 4 4 3 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.3 001259961.2_18529001_3 - 0.013 15.3 0.1 0.92 9.5 0.0 3.4 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain EphA2_TM PF14575.4 001259961.2_18529001_3 - 0.023 15.4 0.0 0.084 13.6 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.4 001259961.2_18529001_3 - 0.22 11.8 2.9 0.29 11.5 0.6 2.4 2 0 0 2 2 1 0 SCIMP protein TMEM154 PF15102.4 001259961.2_18529001_3 - 0.42 10.4 6.7 0.032 14.0 0.6 2.4 2 0 0 2 2 2 0 TMEM154 protein family Homeobox PF00046.27 001259965.2_18522001_1 - 1.3e-20 72.9 6.4 1.8e-20 72.4 4.4 2.2 2 0 0 2 2 2 1 Homeobox domain Mitoc_L55 PF09776.7 001259965.2_18522001_1 - 0.011 15.3 1.4 0.024 14.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 Homeobox_KN PF05920.9 001259965.2_18522001_1 - 0.048 13.4 1.3 0.36 10.6 0.0 2.6 3 0 0 3 3 3 0 Homeobox KN domain Serinc PF03348.13 001275022.1_18524001_1 - 1.5e-149 498.4 17.6 1.9e-149 498.1 17.6 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Serinc PF03348.13 001275018.1_18524001_1 - 1.4e-133 445.8 15.4 1.9e-133 445.4 15.4 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Serinc PF03348.13 001275018.1_18524001_2 - 4.4e-11 42.2 0.1 6.6e-11 41.7 0.1 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) Sporozoite_P67 PF05642.9 140634.2_18524001_2 - 0.0073 14.3 2.2 0.012 13.7 2.2 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Retrotrans_gag PF03732.15 140634.2_18524001_2 - 0.015 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Acyltransf_C PF16076.3 168661.2_18524001_2 - 3.5e-24 84.6 0.0 6.8e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.19 168661.2_18524001_2 - 5.5e-13 48.6 0.1 2e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.3 001275013.1_18524001_1 - 8e-22 77.1 0.0 1.7e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.19 001275013.1_18524001_1 - 4.3e-12 45.7 0.0 7.3e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase YhdB PF14148.4 001275013.1_18524001_1 - 0.05 13.6 0.1 4.9 7.2 0.0 2.6 2 0 0 2 2 2 0 YhdB-like protein Hpre_diP_synt_I PF07456.9 001275013.1_18524001_1 - 0.11 12.4 5.7 0.12 12.3 2.6 2.1 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase component I RRM_1 PF00076.20 168320.2_18525001_3 - 1e-13 50.7 0.0 2.2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 168320.2_18525001_3 - 0.00041 20.3 0.0 0.0013 18.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif Peptidase_M22 PF00814.23 140623.4_18523001_1 - 9.5e-93 310.7 0.0 1.1e-92 310.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.13 140623.4_18523001_1 - 0.068 12.7 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus 60KD_IMP PF02096.18 140029.4_18523001_1 - 1.1e-11 44.8 6.3 5.3e-11 42.6 6.3 1.9 1 1 0 1 1 1 1 60Kd inner membrane protein F-box-like_2 PF13013.4 140029.4_18523001_1 - 0.074 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 F-box-like domain Tetraspannin PF00335.18 168299.2_18525001_2 - 6.7e-46 156.6 7.4 9.1e-46 156.2 7.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF846 PF05832.10 001169920.2_18523001_3 - 9.3e-55 184.3 14.9 1.2e-54 184.0 14.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2207 PF09972.7 001169920.2_18523001_3 - 2.2 6.9 4.8 0.34 9.5 0.6 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) BNIP3 PF06553.10 168865.2_18524001_3 - 1.1e-38 132.8 0.5 1.5e-38 132.3 0.5 1.2 1 0 0 1 1 1 1 BNIP3 BNIP3 PF06553.10 168864.2_18523001_2 - 7e-39 133.4 0.3 1.1e-38 132.7 0.3 1.2 1 0 0 1 1 1 1 BNIP3 Alk_phosphatase PF00245.18 139720.3_18524001_3 - 3.2e-128 428.1 0.3 3.7e-128 427.9 0.3 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.16 139720.3_18524001_3 - 0.015 14.6 0.1 0.026 13.7 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Cut8 PF08559.8 001275183.1_18524001_3 - 3.1e-47 161.1 0.4 5.4e-47 160.3 0.4 1.4 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein TAF4 PF05236.12 001274998.1_18529001_2 - 9.5e-70 235.4 4.9 9.5e-70 235.4 4.9 2.6 4 0 0 4 4 4 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.12 001274998.1_18529001_2 - 2.3e-31 107.5 1.0 2.3e-31 107.5 1.0 3.4 4 0 0 4 4 4 1 NHR1 homology to TAF LRR_8 PF13855.4 140957.4_18527001_3 - 2.7e-39 132.6 21.7 7.9e-11 41.4 0.0 7.1 5 1 2 7 7 7 5 Leucine rich repeat TIR PF01582.18 140957.4_18527001_3 - 2.5e-18 66.3 0.9 4.7e-18 65.5 0.9 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 140957.4_18527001_3 - 8.5e-14 51.3 26.2 0.00056 20.1 1.5 9.0 3 1 8 11 11 11 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 140957.4_18527001_3 - 6.1e-09 35.8 5.6 0.0014 18.5 0.1 4.3 2 1 2 4 4 4 2 Leucine rich repeats (6 copies) TIR_2 PF13676.4 140957.4_18527001_3 - 1.4e-07 31.6 0.0 3.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 140957.4_18527001_3 - 6.6e-05 22.4 3.8 0.74 9.2 0.0 3.9 2 2 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.31 140957.4_18527001_3 - 0.0012 18.8 22.0 27 5.6 0.0 10.7 10 2 0 10 10 10 0 Leucine Rich Repeat LRR_6 PF13516.4 140957.4_18527001_3 - 1.7 8.8 30.2 4.5 7.4 0.2 9.8 11 0 0 11 11 11 0 Leucine Rich repeat Med19 PF10278.7 001300174.1_18524001_2 - 6.7e-78 260.6 15.3 9.1e-78 260.1 15.3 1.2 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.7 001300174.1_18524001_2 - 0.05 13.1 12.7 0.1 12.0 12.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.12 001300174.1_18524001_2 - 0.13 10.4 1.0 0.17 10.0 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.27 140752.3_18525001_1 - 5.6e-40 136.8 0.0 1.5e-39 135.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 140752.3_18525001_1 - 3.8e-29 101.2 0.0 1.9e-28 98.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 140752.3_18525001_1 - 8.1e-10 38.8 0.1 9.1e-09 35.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.4 140752.3_18525001_1 - 2.5e-05 24.5 0.1 8.1e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.4 140752.3_18525001_1 - 0.01 15.5 0.0 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain HEM4 PF02602.13 140752.3_18525001_1 - 0.013 14.8 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD AAA_19 PF13245.4 140752.3_18525001_1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.12 140752.3_18525001_1 - 0.021 14.5 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.12 140752.3_18525001_1 - 0.076 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Sema PF01403.17 001169959.2_18529001_2 - 2.3e-109 365.8 0.3 3.3e-109 365.3 0.3 1.2 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.17 001169959.2_18529001_2 - 1.3e-41 140.4 98.7 2.4e-10 40.3 9.9 7.8 7 1 0 7 7 7 6 Thrombospondin type 1 domain PSI PF01437.23 001169959.2_18529001_2 - 2.9e-06 27.6 7.3 2.9e-06 27.6 7.3 4.2 4 1 0 4 4 4 1 Plexin repeat HMG_box PF00505.17 001274901.1_18524001_2 - 2.4e-26 91.8 2.7 4.6e-26 90.9 2.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001274901.1_18524001_2 - 9.7e-10 38.8 0.5 2.2e-09 37.7 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain CBM_14 PF01607.22 001169956.1_18524001_2 - 1.6e-26 92.1 55.8 2.4e-08 33.9 3.5 6.1 4 1 2 6 6 6 5 Chitin binding Peritrophin-A domain MRP-S31 PF15433.4 079376.3_18523001_2 - 1.9e-94 316.7 2.7 2.7e-94 316.2 2.5 1.3 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 VSG_B PF13206.4 079376.3_18523001_2 - 0.0042 16.3 3.3 0.0062 15.7 3.3 1.2 1 0 0 1 1 1 1 Trypanosomal VSG domain Myosin_tail_1 PF01576.17 079258.3_18528001_1 - 1.8e-77 261.1 148.9 2.5e-77 260.6 148.9 1.1 1 0 0 1 1 1 1 Myosin tail SlyX PF04102.10 079258.3_18528001_1 - 0.0049 17.3 1.1 0.0049 17.3 1.1 11.3 5 3 7 13 13 13 3 SlyX SNF2_N PF00176.21 168641.1_18529001_3 - 4.1e-73 246.0 1.5 4.1e-73 246.0 1.5 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.29 168641.1_18529001_3 - 8.9e-20 71.0 0.1 8.5e-19 67.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain BRK PF07533.14 168641.1_18529001_3 - 4.1e-18 64.6 0.2 9.7e-18 63.4 0.2 1.7 1 0 0 1 1 1 1 BRK domain Bromodomain PF00439.23 168641.1_18529001_3 - 5.6e-18 64.7 0.8 1.4e-17 63.4 0.8 1.7 1 0 0 1 1 1 1 Bromodomain HSA PF07529.11 168641.1_18529001_3 - 8.6e-18 64.3 18.9 8.6e-18 64.3 18.9 4.6 5 0 0 5 5 5 1 HSA SnAC PF14619.4 168641.1_18529001_3 - 2.4e-14 53.6 6.9 2.4e-14 53.6 6.9 5.4 5 1 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.9 168641.1_18529001_3 - 3.3e-09 36.2 1.8 3.3e-09 36.2 1.8 3.4 3 0 0 3 3 3 1 QLQ NAD_binding_1 PF00175.19 001300106.1_18524001_2 - 7.1e-36 123.0 0.0 2.1e-28 99.0 0.0 2.9 2 1 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.22 001300106.1_18524001_2 - 4.1e-35 119.9 0.0 6.7e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.10 001300106.1_18524001_2 - 9.9e-07 28.9 0.0 4.4e-06 26.8 0.0 2.1 2 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF3382 PF11862.6 001300106.1_18524001_2 - 0.0068 16.5 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3382) Phage_TAC_6 PF09550.8 001300106.1_18524001_2 - 0.0087 16.3 0.3 0.017 15.4 0.3 1.5 1 0 0 1 1 1 1 Phage tail assembly chaperone protein, TAC Sec66 PF09802.7 001300106.1_18524001_2 - 0.046 13.2 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 COX16 PF14138.4 001300106.1_18524001_2 - 0.13 12.7 0.0 0.32 11.4 0.0 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 WD40 PF00400.30 001274794.1_18524001_2 - 0.00031 21.4 2.9 1.5 9.7 0.5 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat IpaC_SipC PF09599.8 001274794.1_18524001_2 - 0.0087 15.5 0.4 0.011 15.1 0.4 1.1 1 0 0 1 1 1 1 Salmonella-Shigella invasin protein C (IpaC_SipC) Aldo_ket_red PF00248.19 001274787.1_18523001_2 - 1.2e-52 178.8 0.1 2.4e-52 177.8 0.1 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family MADF_DNA_bdg PF10545.7 140203.1_18525001_1 - 4e-22 78.2 11.2 8.4e-12 45.1 0.6 2.8 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.4 140203.1_18525001_1 - 0.0013 18.9 3.6 0.029 14.6 0.4 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain KaiA PF07688.10 140203.1_18525001_1 - 0.078 13.0 0.4 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 KaiA C-terminal domain PDGF_N PF04692.11 001014585.2_18526001_1 - 8.3 7.2 8.1 7.3 7.4 6.0 2.0 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region DCP2 PF05026.11 001014585.2_18526001_2 - 7.9e-31 106.1 0.4 4.8e-29 100.4 0.2 2.6 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.26 001014585.2_18526001_2 - 4.1e-15 55.8 0.0 1.6e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Rossmann-like PF10727.7 001014585.2_18526001_2 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Rossmann-like domain NARP1 PF12569.6 206395.3_18527001_3 - 0.78 8.4 14.1 1.3 7.6 14.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SAPS PF04499.13 206395.3_18527001_3 - 2 7.0 6.0 0.78 8.3 0.8 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF4746 PF15928.3 206395.3_18527001_3 - 3.2 7.0 12.0 0.45 9.8 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CDC45 PF02724.12 206395.3_18527001_3 - 5.4 5.1 12.3 0.03 12.5 2.8 1.9 2 0 0 2 2 2 0 CDC45-like protein Cyclin_N PF00134.21 079403.4_18529001_3 - 2.4e-24 85.4 2.4 9.6e-22 77.0 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.17 079403.4_18529001_3 - 0.026 14.4 1.5 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 Cyclin, C-terminal domain NARP1 PF12569.6 079403.4_18529001_3 - 1.1 7.9 14.2 2 7.1 14.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4746 PF15928.3 079403.4_18529001_3 - 5.7 6.1 11.9 0.65 9.2 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Tim54 PF11711.6 079403.4_18529001_3 - 5.8 5.4 10.8 23 3.5 10.8 2.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FRG1 PF06229.10 140945.3_18522001_3 - 3.4e-78 261.6 0.6 3.4e-78 261.6 0.6 1.6 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.11 140945.3_18522001_3 - 0.00037 20.5 0.0 0.00096 19.2 0.0 1.6 1 1 0 1 1 1 1 Fascin domain DUF569 PF04601.11 140945.3_18522001_3 - 0.065 12.8 0.2 0.42 10.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF569) IFNGR1 PF07140.9 140945.3_18522001_3 - 0.092 12.7 0.1 0.092 12.7 0.1 1.8 2 0 0 2 2 2 0 Interferon gamma receptor (IFNGR1) HSP70 PF00012.18 001202172.2_18527001_3 - 8.1e-172 572.4 1.7 1.1e-171 572.0 1.7 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001202172.2_18527001_3 - 1.9e-09 36.7 0.0 3.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.18 001202173.2_18527001_2 - 8e-172 572.4 1.7 1e-171 572.0 1.7 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001202173.2_18527001_2 - 1.9e-09 36.7 0.0 3.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein ADP_PFK_GK PF04587.13 140428.4_18526001_3 - 3.6e-141 470.5 0.0 4.2e-141 470.2 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region GST_N_3 PF13417.4 139980.3_18522001_2 - 1.9e-19 69.6 0.2 3.6e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 139980.3_18522001_2 - 5.2e-14 52.2 0.1 9.3e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 139980.3_18522001_2 - 8.5e-12 45.1 0.1 1.9e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 139980.3_18522001_2 - 3.2e-06 26.9 0.0 6.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 139980.3_18522001_2 - 0.00017 21.6 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 139980.3_18522001_2 - 0.0077 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin Pribosyl_synth PF14572.4 001274712.1_18525001_3 - 2.9e-44 151.2 2.4 3e-37 128.4 0.9 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.4 001274712.1_18525001_3 - 2.3e-43 146.7 0.5 7e-43 145.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.25 001274712.1_18525001_3 - 3.4e-15 55.8 1.6 4.3e-15 55.5 0.4 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.4 001274712.1_18525001_3 - 0.00075 18.9 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Zip PF02535.20 001274655.1_18527001_3 - 5.1e-109 364.4 11.4 3e-65 220.5 12.9 3.1 2 2 1 3 3 3 2 ZIP Zinc transporter ArfGap PF01412.16 001275288.1_18525001_2 - 3.4e-31 107.6 1.4 9.2e-31 106.2 1.4 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ribosomal_L26 PF16906.3 001275096.1_18522001_1 - 1.8e-41 140.4 3.6 2.5e-41 139.9 3.6 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.27 001275096.1_18522001_1 - 8e-07 28.7 4.1 8e-07 28.7 4.1 2.2 2 0 0 2 2 2 1 KOW motif Mito_carr PF00153.25 167800.3_18523001_2 - 5.9e-14 51.6 0.1 1.7e-07 30.9 0.0 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein COesterase PF00135.26 176322.3_18524001_3 - 3.1e-129 432.1 0.0 3.6e-129 431.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 176322.3_18524001_3 - 7.5e-07 29.1 0.0 1.7e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 176322.3_18524001_3 - 0.089 13.3 0.1 0.16 12.5 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family CBM_14 PF01607.22 140934.2_18523001_1 - 8.9e-20 70.5 60.2 5.4e-08 32.8 6.6 5.5 5 0 0 5 5 5 5 Chitin binding Peritrophin-A domain Anoctamin PF04547.10 001274804.1_18529001_3 - 9.2e-163 541.9 16.1 1.1e-162 541.6 16.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.3 001274804.1_18529001_3 - 1.1e-61 208.4 0.5 1.9e-61 207.5 0.5 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Atrophin-1 PF03154.13 001274651.1_18529001_3 - 7.7e-13 47.5 82.9 7.7e-13 47.5 82.9 8.1 2 2 4 7 7 7 1 Atrophin-1 family ELM2 PF01448.22 001274651.1_18529001_3 - 2.8e-10 40.7 0.0 1.6e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-bind_7 PF15963.3 001274651.1_18529001_3 - 0.00032 20.4 0.1 0.00032 20.4 0.1 2.6 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.29 001274651.1_18529001_3 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain COPIIcoated_ERV PF07970.10 140501.3_18523001_2 - 6.4e-76 254.9 1.1 8.3e-76 254.6 1.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.4 140501.3_18523001_2 - 8.9e-28 96.3 0.4 6e-27 93.7 0.1 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CSD PF00313.20 001300054.1_18529001_2 - 3.2e-60 199.7 16.9 1.5e-11 43.9 0.0 8.6 8 0 0 8 8 8 6 'Cold-shock' DNA-binding domain S1-like PF14444.4 001300054.1_18529001_2 - 1.3e-07 31.4 6.6 0.045 13.7 0.0 5.3 5 0 0 5 5 5 2 S1-like DUF4232 PF14016.4 001300054.1_18529001_2 - 0.0043 17.1 0.0 6.3 6.8 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4232) YcgR_2 PF12945.5 001300054.1_18529001_2 - 0.037 14.1 0.7 8.4 6.5 0.0 3.4 3 0 0 3 3 3 0 Flagellar protein YcgR AMP-binding PF00501.26 001274263.1_18529001_3 - 6.9e-83 278.4 0.0 1.5e-52 178.5 0.0 2.7 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.9 001274263.1_18529001_3 - 6e-31 107.4 8.8 1.3e-27 96.6 0.2 2.7 2 0 0 2 2 2 2 DMAP1-binding Domain GvpG PF05120.10 001274263.1_18529001_3 - 0.0033 17.3 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Ras PF00071.20 079246.4_18523001_2 - 8.4e-60 200.9 0.5 1.1e-59 200.5 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 079246.4_18523001_2 - 2e-35 121.5 0.4 3.1e-35 120.9 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 079246.4_18523001_2 - 4.6e-18 65.1 0.1 6.3e-18 64.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 079246.4_18523001_2 - 1.2e-07 31.2 0.1 1.6e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 079246.4_18523001_2 - 1.3e-06 28.0 0.5 4.9e-05 22.8 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 079246.4_18523001_2 - 0.00034 20.5 0.1 0.00074 19.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.8 079246.4_18523001_2 - 0.0018 17.6 0.0 0.0039 16.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.16 079246.4_18523001_2 - 0.087 12.2 0.3 0.18 11.2 0.3 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.4 079246.4_18523001_2 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain FOLN PF09289.8 079246.4_18523001_2 - 0.13 12.3 0.8 0.37 10.9 0.8 1.8 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain UPF0183 PF03676.12 139954.2_18525001_3 - 8.6e-161 535.5 0.2 1e-160 535.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) DUF229 PF02995.15 001274649.1_18526001_3 - 2.3e-160 534.3 0.0 3.1e-160 533.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.21 001274649.1_18526001_3 - 4.8e-07 29.3 0.1 1.9e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 Sulfatase YqbF PF14553.4 001274649.1_18526001_3 - 0.13 12.0 0.2 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 YqbF, hypothetical protein domain DnaJ PF00226.29 141123.3_18522001_3 - 6.4e-25 86.9 1.5 1.1e-24 86.2 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain Aldedh PF00171.20 141111.6_18526001_2 - 4.7e-102 341.7 0.0 5.9e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DHNA PF04038.10 141111.6_18526001_2 - 0.16 12.4 0.1 0.76 10.2 0.1 2.0 1 1 1 2 2 2 0 Dihydroneopterin aldolase VPS9 PF02204.16 141090.3_18529001_3 - 1.3e-19 70.2 0.4 1.8e-18 66.5 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.18 141090.3_18529001_3 - 6e-14 50.9 28.8 0.012 15.3 0.1 8.3 8 0 0 8 8 8 6 MORN repeat RCC1 PF00415.16 141090.3_18529001_3 - 1e-12 48.3 0.1 1.2e-05 25.7 0.0 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 141090.3_18529001_3 - 6.9e-10 38.3 4.2 2.9e-06 26.8 0.4 4.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat DUF5137 PF17220.1 141090.3_18529001_3 - 0.28 11.9 1.1 0.7 10.6 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5137) Med1 PF10744.7 001275254.1_18529001_2 - 5.1e-64 216.7 0.2 7.3e-64 216.1 0.2 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Iso_dh PF00180.18 176298.2_18524001_2 - 1.6e-73 247.7 0.0 2.2e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase L71 PF02448.13 001274960.1_18522001_3 - 1.8e-21 76.2 7.1 2.5e-21 75.7 7.1 1.2 1 0 0 1 1 1 1 L71 family UQ_con PF00179.24 139930.2_18522001_2 - 4.3e-39 133.2 0.1 6.8e-39 132.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Biopterin_H PF00351.19 001014573.2_18524001_2 - 5.3e-174 577.8 0.0 6.4e-174 577.5 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.23 001014573.2_18524001_2 - 2.2e-05 24.0 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ACT domain Mito_carr PF00153.25 139666.2_18523001_2 - 1e-59 198.3 6.3 1.1e-21 76.4 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Trypsin PF00089.24 001300170.1_18523001_3 - 3e-55 187.3 0.1 3.5e-55 187.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001300170.1_18523001_3 - 3.7e-06 27.8 0.0 5.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001300170.1_18523001_3 - 0.026 14.8 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Serglycin PF04360.10 001275057.1_18525001_1 - 0.071 12.9 0.7 0.13 12.1 0.7 1.3 1 0 0 1 1 1 0 Serglycin Neur_chan_LBD PF02931.21 001275057.1_18525001_2 - 1.6e-47 161.6 1.2 2.2e-47 161.2 1.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001275057.1_18525001_2 - 9.6e-23 81.3 5.6 9.6e-22 78.1 5.6 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Chitin_bind_4 PF00379.21 001300211.1_18522001_2 - 3.2e-11 43.5 3.2 5.2e-11 42.8 3.2 1.4 1 0 0 1 1 1 1 Insect cuticle protein Alanine_zipper PF11839.6 001300211.1_18522001_2 - 0.11 12.7 0.2 0.16 12.2 0.2 1.2 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein FERM_M PF00373.16 140690.3_18526001_1 - 1.2e-39 135.2 0.0 2.1e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 FERM central domain PH PF00169.27 140690.3_18526001_1 - 2.2e-07 31.2 0.0 4.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 PH domain TMEM190 PF15431.4 140690.3_18526001_3 - 0.026 14.5 0.7 0.042 13.9 0.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 RRM_1 PF00076.20 139369.2_18528001_3 - 8.1e-32 108.7 0.2 9.8e-08 31.6 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.10 139369.2_18528001_3 - 0.00066 19.8 1.5 0.00066 19.8 1.5 3.9 5 0 0 5 5 5 1 Protein of unknown function (DUF1777) Nup35_RRM PF05172.11 139369.2_18528001_3 - 0.023 14.5 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1669 PF07894.10 139369.2_18528001_3 - 1.3 8.4 6.5 2.4 7.5 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Tcf25 PF04910.12 001274629.1_18525001_3 - 1.1e-101 340.2 5.6 1.7e-101 339.6 5.6 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Coilin_N PF15862.3 001274629.1_18525001_3 - 0.89 9.2 6.4 1.8 8.2 6.4 1.5 1 0 0 1 1 1 0 Coilin N-terminus ATP-synt_E PF05680.10 001274629.1_18525001_3 - 1 9.6 4.9 3 8.1 4.9 1.7 1 0 0 1 1 1 0 ATP synthase E chain PGA2 PF07543.10 001274629.1_18525001_3 - 1.1 9.1 5.3 3 7.7 5.3 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 CTP_transf_1 PF01148.18 001300047.1_18526001_1 - 2.1e-88 296.4 25.0 2.7e-88 296.1 25.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family FGGY_N PF00370.19 139398.3_18525001_2 - 9.2e-63 211.9 0.2 1.4e-62 211.3 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.14 139398.3_18525001_2 - 1.1e-54 185.0 0.1 2.9e-54 183.7 0.1 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Ank_2 PF12796.5 140149.3_18523001_2 - 5.2e-14 52.5 1.4 3.1e-06 27.6 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.4 140149.3_18523001_2 - 5.3e-12 45.9 2.6 2e-07 31.3 0.3 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zf-MYND PF01753.16 140149.3_18523001_2 - 9.7e-10 38.2 17.0 9.7e-10 38.2 17.0 2.0 2 0 0 2 2 2 1 MYND finger Ank_3 PF13606.4 140149.3_18523001_2 - 2e-09 36.8 0.6 0.00082 19.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.4 140149.3_18523001_2 - 2.5e-09 37.1 0.7 0.00046 20.4 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.28 140149.3_18523001_2 - 5.6e-08 32.8 0.8 0.00083 19.6 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat PolC_DP2 PF03833.11 140149.3_18523001_2 - 0.055 11.2 3.6 0.082 10.6 3.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Tom37 PF10568.7 140904.2_18523001_3 - 3e-24 85.6 0.0 1.3e-23 83.6 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.2 140904.2_18523001_3 - 4e-19 69.1 0.0 7.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.2 140904.2_18523001_3 - 9.1e-17 60.5 0.2 2.2e-16 59.3 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 140904.2_18523001_3 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SWIM PF04434.15 140904.2_18523001_3 - 0.065 12.8 0.7 0.16 11.5 0.7 1.7 1 0 0 1 1 1 0 SWIM zinc finger CHDCT2 PF08074.9 001170005.2_18529001_2 - 7.8e-90 299.5 0.3 2.3e-89 298.0 0.3 1.9 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain SNF2_N PF00176.21 001170005.2_18529001_2 - 9.2e-60 202.1 0.0 1.8e-59 201.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1086 PF06461.9 001170005.2_18529001_2 - 1.5e-59 199.7 0.0 1.2e-58 196.7 0.0 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) DUF1087 PF06465.11 001170005.2_18529001_2 - 5.3e-26 90.3 3.1 5.3e-26 90.3 3.1 3.7 3 0 0 3 3 2 1 Domain of Unknown Function (DUF1087) CHDNT PF08073.10 001170005.2_18529001_2 - 1.9e-25 88.4 0.1 4.6e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 CHDNT (NUC034) domain Chromo PF00385.22 001170005.2_18529001_2 - 6.3e-23 80.3 3.5 4.1e-14 52.1 0.1 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.27 001170005.2_18529001_2 - 3.2e-21 74.8 25.5 1e-10 41.2 6.9 2.5 2 0 0 2 2 2 2 PHD-finger Helicase_C PF00271.29 001170005.2_18529001_2 - 6.9e-21 74.6 0.0 1.4e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001170005.2_18529001_2 - 1.1e-09 38.4 0.0 4.8e-09 36.3 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.6 001170005.2_18529001_2 - 7.9e-08 31.7 0.0 7.9e-08 31.7 0.0 2.0 2 0 0 2 2 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.27 001170005.2_18529001_2 - 0.011 15.4 0.0 0.034 13.8 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase PHD_2 PF13831.4 001170005.2_18529001_2 - 0.035 13.5 9.6 0.39 10.1 1.7 2.6 2 0 0 2 2 2 0 PHD-finger AAA_22 PF13401.4 001170005.2_18529001_2 - 0.073 13.2 0.1 0.33 11.1 0.0 2.3 2 0 0 2 2 1 0 AAA domain NUDE_C PF04880.11 001104099.2_18524001_2 - 2.8e-10 40.9 5.3 2.8e-10 40.9 5.3 3.3 2 1 1 3 3 3 1 NUDE protein, C-terminal conserved region GAS PF13851.4 001104099.2_18524001_2 - 0.014 14.6 29.3 0.015 14.5 16.1 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.3 001104099.2_18524001_2 - 0.1 12.0 23.0 0.2 10.9 23.0 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3391 PF11871.6 001104099.2_18524001_2 - 0.36 11.3 4.4 1 9.8 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF3450 PF11932.6 001104099.2_18524001_2 - 1.3 8.1 20.0 0.03 13.5 3.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF745 PF05335.11 001104099.2_18524001_2 - 1.4 8.5 7.4 3.4 7.2 7.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) APG6 PF04111.10 001104099.2_18524001_2 - 1.5 8.0 27.3 0.52 9.5 12.9 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 PilJ PF13675.4 001104099.2_18524001_2 - 1.9 8.4 6.5 2.8 7.9 1.0 3.0 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.10 001104099.2_18524001_2 - 2.5 8.0 14.1 1.3 8.9 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.13 001104099.2_18524001_2 - 2.5 8.4 22.1 4.5 7.5 8.4 2.8 1 1 3 4 4 4 0 Fez1 UPF0184 PF03670.11 001104099.2_18524001_2 - 7.3 6.9 13.3 0.93 9.8 1.5 3.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Exonuc_VII_L PF02601.13 001104099.2_18524001_2 - 9 5.6 14.2 7.7 5.9 13.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.6 001104099.2_18524001_2 - 9.5 6.2 19.8 0.6 10.0 4.5 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding NUDE_C PF04880.11 001300088.1_18525001_2 - 2e-12 47.8 4.7 2e-12 47.8 4.7 2.1 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region GAS PF13851.4 001300088.1_18525001_2 - 0.01 15.1 27.4 0.03 13.6 16.2 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.3 001300088.1_18525001_2 - 0.15 11.3 22.8 0.32 10.3 22.8 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3450 PF11932.6 001300088.1_18525001_2 - 2.3 7.3 19.5 0.045 12.9 3.4 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) APG6 PF04111.10 001300088.1_18525001_2 - 3.2 6.9 27.2 0.68 9.1 12.8 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.10 001300088.1_18525001_2 - 4 7.3 13.6 1.8 8.4 2.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.7 001300088.1_18525001_2 - 9 6.4 9.1 53 4.0 4.1 3.4 2 1 0 3 3 3 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.7 001300046.1_18529001_3 - 8e-53 178.7 23.4 8e-53 178.7 23.4 3.5 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.3 001300046.1_18529001_3 - 2e-30 104.6 10.0 2e-30 104.6 10.0 4.1 3 1 1 4 4 4 1 JNK-interacting protein leucine zipper II Atg14 PF10186.7 001300046.1_18529001_3 - 0.0075 15.3 25.5 0.095 11.6 8.7 2.6 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3373 PF11853.6 001300046.1_18529001_3 - 0.028 13.0 2.8 0.34 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Pox_A_type_inc PF04508.10 001300046.1_18529001_3 - 0.63 9.9 3.1 0.98 9.3 1.7 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat zf-C4 PF00105.16 168756.2_18529001_1 - 3.7e-31 107.3 15.1 1.2e-30 105.6 15.1 2.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 168756.2_18529001_1 - 8.7e-20 71.1 0.0 1.6e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor HCO3_cotransp PF00955.19 168374.2_18529001_2 - 1.2e-194 647.8 8.4 1.5e-194 647.5 8.4 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.11 168374.2_18529001_2 - 7.3e-119 396.4 0.0 7.3e-119 396.4 0.0 1.6 2 0 0 2 2 2 1 Band 3 cytoplasmic domain DUF3681 PF12442.6 168374.2_18529001_2 - 0.025 15.0 0.1 0.37 11.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) PTS_EIIA_2 PF00359.20 168374.2_18529001_2 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Pro_isomerase PF00160.19 001274707.1_18523001_1 - 3.1e-39 134.7 0.1 5.8e-39 133.8 0.0 1.5 2 0 0 2 2 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.15 001274707.1_18523001_1 - 8.9e-13 47.2 8.8 0.00023 20.9 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.26 001274707.1_18523001_1 - 5.2e-11 41.7 4.6 0.00015 21.3 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.4 001274707.1_18523001_1 - 1.2e-08 34.3 7.1 0.015 14.8 0.9 3.5 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.4 001274707.1_18523001_1 - 3.2e-07 29.9 3.2 0.17 12.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.4 001274707.1_18523001_1 - 1.4e-06 28.8 3.3 0.00015 22.2 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.4 001274707.1_18523001_1 - 2.8e-05 24.4 1.0 1.5 9.7 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.4 001274707.1_18523001_1 - 0.00016 21.7 4.9 0.12 12.5 0.5 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.4 001274707.1_18523001_1 - 0.00016 21.9 1.3 0.00064 20.1 0.1 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.4 001274707.1_18523001_1 - 0.00026 21.0 0.9 0.014 15.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001274707.1_18523001_1 - 0.0061 16.6 1.9 0.084 13.0 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.4 001274707.1_18523001_1 - 0.0096 15.8 7.1 0.16 11.9 0.0 3.4 2 2 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Ribonuc_2-5A PF06479.10 001274707.1_18523001_1 - 0.024 14.7 0.1 0.065 13.3 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease 2-5A DUF3856 PF12968.5 001274707.1_18523001_1 - 0.089 12.7 0.2 2.5 8.0 0.2 2.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.4 001274707.1_18523001_1 - 0.24 11.4 3.5 14 5.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.4 001274707.1_18523001_1 - 0.34 11.5 5.8 2.2 9.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RRN9 PF10680.7 001274707.1_18523001_2 - 0.028 14.6 1.6 0.059 13.5 1.6 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor APS_kinase PF01583.18 001275143.1_18525001_1 - 2.1e-72 242.0 0.0 3.2e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.15 001275143.1_18525001_1 - 2.7e-69 232.8 0.0 4e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.4 001275143.1_18525001_1 - 4.4e-46 156.3 0.0 6e-45 152.6 0.0 2.2 2 0 0 2 2 2 1 PUA-like domain AAA_33 PF13671.4 001275143.1_18525001_1 - 0.00021 21.4 0.0 0.00054 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001275143.1_18525001_1 - 0.022 15.1 0.0 0.064 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.4 001275143.1_18525001_1 - 0.087 13.1 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.13 001275143.1_18525001_1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 NTPase Arf PF00025.19 057607.6_18524001_1 - 2.6e-78 261.3 0.1 3.8e-78 260.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 057607.6_18524001_1 - 1.1e-13 50.9 0.0 1.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.11 057607.6_18524001_1 - 7.5e-13 48.6 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 057607.6_18524001_1 - 1.4e-11 44.1 0.0 1.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.18 057607.6_18524001_1 - 2.9e-10 39.7 1.0 7.4e-07 28.5 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.10 057607.6_18524001_1 - 3.8e-09 36.1 0.0 5.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 057607.6_18524001_1 - 0.00035 20.5 0.0 0.00059 19.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase BACK PF07707.13 206283.2_18525001_1 - 4.8e-05 23.3 0.1 0.00013 21.9 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.29 206283.2_18525001_1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Sugar_tr PF00083.22 001103997.3_18525001_2 - 1.4e-135 452.5 18.5 1.8e-135 452.2 18.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001103997.3_18525001_2 - 2e-22 79.4 26.1 2e-22 79.4 26.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily R3H PF01424.20 001104027.2_18529001_2 - 8e-13 48.1 0.0 1.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 R3H domain SUZ PF12752.5 001104027.2_18529001_2 - 1.1e-08 35.6 0.4 1.1e-08 35.6 0.4 5.5 4 0 0 4 4 4 1 SUZ domain DOR PF14839.4 001104033.2_18524001_3 - 1.2e-33 117.0 15.4 2e-25 90.0 11.3 4.2 5 0 0 5 5 5 2 DOR family Ank_2 PF12796.5 001104063.2_18529001_1 - 1e-143 468.1 50.0 9.7e-17 61.2 1.3 11.8 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.28 001104063.2_18529001_1 - 3.7e-131 422.2 68.8 1.2e-07 31.7 0.0 23.9 24 0 0 24 24 24 22 Ankyrin repeat Ank_4 PF13637.4 001104063.2_18529001_1 - 8.8e-129 418.3 78.3 5.8e-12 45.8 1.2 17.6 3 3 20 23 23 23 21 Ankyrin repeats (many copies) Ank_5 PF13857.4 001104063.2_18529001_1 - 8.3e-112 363.1 53.7 4.3e-12 45.9 0.1 17.4 3 3 15 20 20 20 19 Ankyrin repeats (many copies) Ank_3 PF13606.4 001104063.2_18529001_1 - 1.3e-110 347.7 45.9 4.3e-06 26.5 0.0 24.4 24 0 0 24 24 24 20 Ankyrin repeat ZU5 PF00791.18 001104063.2_18529001_1 - 2e-27 95.3 0.4 2.6e-26 91.7 0.1 2.5 2 0 0 2 2 2 1 ZU5 domain PK_C PF02887.14 001104063.2_18529001_1 - 0.00026 21.1 0.3 3.8 7.6 0.0 4.3 4 1 1 5 5 5 2 Pyruvate kinase, alpha/beta domain Ank_2 PF12796.5 001104068.2_18529001_1 - 9.2e-138 449.1 50.3 3.4e-16 59.5 1.3 11.8 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.28 001104068.2_18529001_1 - 4.4e-120 387.2 66.6 3.8e-07 30.1 0.0 23.8 23 0 0 23 23 23 20 Ankyrin repeat Ank_4 PF13637.4 001104068.2_18529001_1 - 4.1e-106 346.0 73.5 1.9e-11 44.1 1.2 16.3 3 3 15 20 20 20 19 Ankyrin repeats (many copies) Ank_5 PF13857.4 001104068.2_18529001_1 - 4.7e-105 341.6 49.0 1.4e-11 44.2 0.1 16.3 5 4 13 18 18 18 18 Ankyrin repeats (many copies) Ank_3 PF13606.4 001104068.2_18529001_1 - 3.7e-98 309.4 45.9 1.4e-05 24.9 0.0 24.4 24 0 0 24 24 24 19 Ankyrin repeat ZU5 PF00791.18 001104068.2_18529001_1 - 8e-32 109.3 1.3 9.1e-26 89.9 0.1 2.8 2 0 0 2 2 2 2 ZU5 domain Death PF00531.20 001104068.2_18529001_1 - 2.4e-15 56.3 0.0 7.2e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Death domain ER-remodelling PF14755.4 001104068.2_18529001_1 - 0.00048 20.3 4.9 0.00048 20.3 4.9 3.1 2 0 0 2 2 2 1 Intracellular membrane remodeller PK_C PF02887.14 001104068.2_18529001_1 - 0.0083 16.2 0.2 13 5.9 0.0 4.0 3 1 0 3 3 3 1 Pyruvate kinase, alpha/beta domain FSA_C PF10479.7 001104082.1_18523001_1 - 2.9 5.8 12.5 3.5 5.5 12.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PSI PF01437.23 001104082.1_18523001_1 - 4.6 7.7 10.6 2 8.9 1.0 2.9 2 0 0 2 2 2 0 Plexin repeat RRM_1 PF00076.20 001104102.4_18528001_2 - 1.2e-16 60.2 0.1 2.7e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.24 079442.3_18528001_3 - 1.4e-13 50.5 3.1 3.3e-13 49.2 3.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cnn_1N PF07989.9 079442.3_18528001_3 - 0.079 13.0 1.3 0.32 11.0 1.3 2.0 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 OmpH PF03938.12 079442.3_18528001_3 - 0.16 11.8 2.2 0.48 10.3 2.2 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ZapB PF06005.10 079442.3_18528001_3 - 2.8 8.3 9.0 0.74 10.2 0.2 3.6 3 0 0 3 3 3 0 Cell division protein ZapB Peptidase_M14 PF00246.22 001274591.1_18524001_1 - 3.7e-69 233.6 0.0 4.4e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Arm PF00514.21 079443.2_18525001_2 - 4.4e-84 274.1 11.4 2.2e-14 52.8 0.0 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.18 079443.2_18525001_2 - 5e-23 81.1 4.7 1.5e-22 79.6 4.7 1.9 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.3 079443.2_18525001_2 - 5.2e-23 80.2 1.4 1.6e-22 78.6 0.8 2.1 3 0 0 3 3 3 1 Atypical Arm repeat HEAT_EZ PF13513.4 079443.2_18525001_2 - 2.2e-18 66.2 0.6 1.3e-07 31.7 0.0 5.8 4 3 2 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.4 079443.2_18525001_2 - 2.7e-14 53.2 0.2 1e-05 25.7 0.0 4.8 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.20 079443.2_18525001_2 - 2.6e-12 45.7 2.9 0.0015 18.4 0.0 7.7 8 0 0 8 8 8 1 HEAT repeat Arm_2 PF04826.11 079443.2_18525001_2 - 3.6e-07 29.8 0.0 0.0054 16.1 0.0 3.0 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.18 079443.2_18525001_2 - 8.7e-05 21.1 0.0 0.00058 18.4 0.0 2.1 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.6 079443.2_18525001_2 - 0.00024 21.1 0.0 0.18 11.8 0.0 3.9 3 1 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.4 079443.2_18525001_2 - 0.01 15.9 4.0 8.3 6.6 0.0 4.7 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.14 079443.2_18525001_2 - 0.068 13.8 0.9 4.8 8.0 0.0 4.3 5 0 0 5 5 3 0 PBS lyase HEAT-like repeat NUSAP PF16006.3 079443.2_18525001_2 - 0.072 12.7 4.9 0.12 12.0 4.9 1.3 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein CTNNBL PF08216.9 079443.2_18525001_2 - 0.097 12.7 2.3 14 5.7 0.0 3.8 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear Ank_2 PF12796.5 001104145.3_18529001_1 - 4.6e-33 113.5 0.5 3.4e-17 62.7 0.1 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001104145.3_18529001_1 - 7.9e-32 109.1 1.1 3e-15 56.2 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.28 001104145.3_18529001_1 - 1.2e-25 88.6 0.8 3e-05 24.2 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.4 001104145.3_18529001_1 - 6.6e-24 83.5 9.3 3.5e-12 46.2 0.4 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 001104145.3_18529001_1 - 1.4e-22 77.2 0.5 3.8e-06 26.7 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat PRKG1_interact PF15898.3 001104145.3_18529001_1 - 1.6e-09 38.4 7.7 1.7e-07 32.0 0.4 6.3 7 2 1 8 8 8 2 cGMP-dependent protein kinase interacting domain DUF2360 PF10152.7 001104145.3_18529001_2 - 1.5 9.1 6.4 0.83 9.9 0.4 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4774 PF15999.3 001104154.3_18523001_3 - 2.6e-37 126.2 13.4 1e-19 69.9 4.5 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4774) Peptidase_M14 PF00246.22 001274586.1_18525001_3 - 5e-83 279.1 0.0 7.8e-83 278.5 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.14 001274586.1_18525001_3 - 0.00014 22.1 0.1 0.00034 20.8 0.1 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide AstE_AspA PF04952.12 001274586.1_18525001_3 - 0.0028 16.6 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family SAND PF01342.19 001275141.1_18525001_3 - 1.7e-23 82.0 1.4 3.9e-23 80.8 0.7 2.1 2 0 0 2 2 2 1 SAND domain zf-MYND PF01753.16 001275141.1_18525001_3 - 5e-10 39.2 13.5 1.6e-09 37.5 13.5 2.0 1 0 0 1 1 1 1 MYND finger BLOC1S3 PF15753.3 001104170.3_18522001_1 - 1.6e-16 60.8 20.3 8.6e-13 48.6 6.2 2.1 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex 1 subunit 3 BST2 PF16716.3 001104170.3_18522001_1 - 0.049 14.1 1.6 0.049 14.1 1.6 1.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DDHD PF02862.15 001104179.2_18525001_2 - 0.3 11.0 13.5 0.23 11.4 11.4 1.8 2 0 0 2 2 2 0 DDHD domain CDC45 PF02724.12 001104179.2_18525001_2 - 0.62 8.2 14.4 1 7.4 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3270 PF11674.6 001104179.2_18525001_2 - 0.75 9.9 0.0 0.75 9.9 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3270) AAA_11 PF13086.4 001104179.2_18525001_2 - 1.3 8.6 16.8 3 7.4 16.8 1.5 1 0 0 1 1 1 0 AAA domain DUF913 PF06025.10 001104179.2_18525001_2 - 1.9 7.2 6.5 3.8 6.2 6.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SH3BGR PF04908.13 001202126.1_18523001_3 - 8.9e-36 121.9 0.1 1.6e-35 121.1 0.1 1.4 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.22 001202126.1_18523001_3 - 0.028 14.5 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Pkinase PF00069.23 079446.4_18525001_3 - 1.8e-59 201.1 0.0 6.5e-59 199.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 079446.4_18525001_3 - 1.4e-28 99.8 0.4 4.2e-21 75.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.12 079446.4_18525001_3 - 0.00014 21.2 0.0 0.00034 19.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.22 079446.4_18525001_3 - 0.0014 19.1 0.1 0.0036 17.8 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.4 079446.4_18525001_3 - 0.0032 16.7 0.1 0.028 13.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PTPlike_phytase PF14566.4 079446.4_18525001_3 - 0.036 14.1 0.6 0.065 13.2 0.6 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate APH PF01636.21 079446.4_18525001_3 - 0.21 11.4 4.4 0.18 11.6 0.2 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family MADF_DNA_bdg PF10545.7 140884.3_18527001_2 - 7.7e-37 125.4 17.3 1e-19 70.5 6.9 3.5 4 0 0 4 4 4 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.4 140884.3_18527001_2 - 6.7e-13 48.7 12.5 2.1e-06 27.9 4.0 2.9 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.29 140884.3_18527001_2 - 0.00028 20.8 5.5 0.01 15.8 0.5 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.4 140884.3_18527001_2 - 0.00043 20.2 9.7 0.051 13.5 3.6 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain SUIM_assoc PF16619.3 140884.3_18527001_2 - 0.043 13.8 0.0 0.043 13.8 0.0 5.4 4 1 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 RNF220 PF15926.3 001275130.2_18527001_3 - 1.6e-14 54.0 4.1 1.6e-14 54.0 4.1 4.1 3 2 1 4 4 4 2 E3 ubiquitin-protein ligase RNF220 NPR3 PF03666.11 168570.1_18525001_2 - 3.4e-38 131.5 4.8 1.1e-30 106.8 1.9 2.4 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.9 168570.1_18525001_2 - 1e-05 24.4 0.1 8.9e-05 21.3 0.0 2.0 2 0 0 2 2 2 1 Nitrogen permease regulator 2 TRAPPC-Trs85 PF12739.5 001275129.1_18529001_2 - 1.7e-114 382.7 5.8 2.5e-114 382.2 5.8 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF2225 PF09986.7 001275129.1_18529001_2 - 0.008 15.8 1.6 0.027 14.1 1.3 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.15 001275129.1_18529001_2 - 0.18 11.9 11.5 11 6.3 0.6 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat RasGEF PF00617.17 001274885.1_18529001_2 - 5.4e-52 176.3 0.3 1.4e-51 175.0 0.3 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.18 001274885.1_18529001_2 - 2.1e-16 59.9 0.1 8.8e-16 57.9 0.1 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.21 001274885.1_18529001_2 - 5.3e-13 49.3 0.0 1.4e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain EF-hand_1 PF00036.30 058045.4_18523001_3 - 2.7e-17 60.8 6.5 0.00065 18.9 0.2 6.2 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.4 058045.4_18523001_3 - 5e-14 50.8 6.9 0.0051 16.5 0.0 6.1 6 0 0 6 6 6 3 EF-hand domain EF-hand_7 PF13499.4 058045.4_18523001_3 - 4.3e-13 49.4 16.3 3.3e-05 24.1 1.4 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.4 058045.4_18523001_3 - 7.7e-10 38.3 10.8 0.39 10.4 0.1 6.2 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.4 058045.4_18523001_3 - 9.6e-07 27.9 13.7 0.0037 16.6 0.2 4.6 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.7 058045.4_18523001_3 - 0.0079 16.4 8.4 1.1 9.5 0.9 3.1 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region PTS_IIB PF02302.15 058045.4_18523001_3 - 0.089 13.4 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Dynactin PF12455.6 140867.2_18529001_1 - 3.2e-57 193.8 9.6 3.2e-57 193.8 9.6 4.9 4 1 1 5 5 5 1 Dynein associated protein CAP_GLY PF01302.23 140867.2_18529001_1 - 3.7e-21 74.8 0.2 6.9e-21 73.9 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF1664 PF07889.10 140867.2_18529001_1 - 9.3 6.1 47.0 0.89 9.4 4.6 6.1 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) Chitin_bind_4 PF00379.21 001275124.1_18529001_3 - 4.2e-13 49.5 3.5 1e-12 48.3 3.5 1.7 1 0 0 1 1 1 1 Insect cuticle protein MBOAT PF03062.17 176349.2_18525001_1 - 4.4e-74 249.8 9.6 7.2e-74 249.1 9.6 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SOSSC PF15925.3 001144501.2_18524001_1 - 8.1e-25 87.9 0.2 1.5e-24 87.1 0.2 1.5 1 0 0 1 1 1 1 SOSS complex subunit C CRF PF00473.15 001144501.2_18524001_1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Corticotropin-releasing factor family MTS PF05175.12 001144501.2_18524001_3 - 4.2e-11 42.5 0.0 6.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.11 001144501.2_18524001_3 - 1e-07 31.5 0.1 1.6e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.13 001144501.2_18524001_3 - 4.8e-06 26.2 0.0 7.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.4 001144501.2_18524001_3 - 3.7e-05 24.2 0.0 9.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001144501.2_18524001_3 - 0.0004 20.1 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.14 001144501.2_18524001_3 - 0.0031 16.7 0.0 0.0072 15.5 0.0 1.4 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.10 001144501.2_18524001_3 - 0.0077 16.7 0.4 0.017 15.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.10 001144501.2_18524001_3 - 0.039 14.5 0.0 0.097 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.16 001144501.2_18524001_3 - 0.058 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Frizzled PF01534.15 001275108.2_18529001_1 - 1.4e-134 448.2 11.9 1.9e-134 447.7 11.9 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.20 001275108.2_18529001_1 - 2e-34 118.5 4.3 4.4e-34 117.4 4.3 1.6 1 0 0 1 1 1 1 Fz domain 7tm_1 PF00001.19 001275108.2_18529001_1 - 0.66 9.0 5.5 1.7 7.7 5.3 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Peptidase_S28 PF05577.10 139810.3_18524001_1 - 3.9e-175 582.7 0.5 4.5e-175 582.5 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.18 139810.3_18524001_1 - 8.4e-05 22.2 0.0 0.0004 20.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sharpin_PH PF16764.3 001274546.1_18523001_2 - 0.11 12.2 0.3 0.26 10.9 0.3 1.6 1 0 0 1 1 1 0 Sharpin PH domain Ldh_1_N PF00056.21 001274546.1_18523001_3 - 1.4e-42 145.0 0.2 2.1e-42 144.4 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001274546.1_18523001_3 - 4.7e-22 78.6 0.1 9.4e-22 77.6 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.14 001274546.1_18523001_3 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase SH2 PF00017.22 139749.3_18524001_1 - 7.5e-12 45.0 0.1 1.4e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 SH2 domain EXS PF03124.12 139743.4_18525001_1 - 5.7e-101 338.0 20.9 7.9e-101 337.5 20.9 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.17 139743.4_18525001_1 - 3.4e-32 112.7 15.3 1e-14 55.2 2.1 3.1 1 1 2 3 3 3 3 SPX domain Keratin_B2_2 PF13885.4 139743.4_18525001_3 - 0.11 12.3 3.3 0.38 10.6 3.3 1.8 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Neur_chan_memb PF02932.14 168321.3_18529001_3 - 2.7e-57 194.5 0.0 1.2e-56 192.3 0.0 2.0 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.21 168321.3_18529001_3 - 9.1e-48 162.4 0.0 1.6e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DnaJ PF00226.29 141027.4_18525001_2 - 6.9e-16 58.0 0.1 1.9e-15 56.6 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.29 141027.4_18525001_2 - 8.6e-15 54.5 0.4 3.8e-09 36.4 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain RAC_head PF16717.3 141027.4_18525001_2 - 9e-13 48.9 12.2 9e-13 48.9 12.2 3.8 3 2 0 3 3 3 1 Ribosome-associated complex head domain Myb_DNA-bind_6 PF13921.4 141027.4_18525001_2 - 2.2e-07 30.9 0.4 0.0013 18.8 0.2 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUP PF00674.16 141027.4_18525001_2 - 0.04 13.9 0.5 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 DUP family Sirohm_synth_C PF14823.4 141027.4_18525001_2 - 0.057 12.9 0.9 0.15 11.6 0.2 2.1 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal ATP-grasp_2 PF08442.8 001300012.1_18524001_2 - 6e-68 228.2 0.9 2.5e-67 226.2 0.3 1.9 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.17 001300012.1_18524001_2 - 6.5e-27 94.1 0.8 1.1e-26 93.4 0.8 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.4 001300012.1_18524001_2 - 1.1e-07 31.5 0.3 2.2e-07 30.4 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.17 001300012.1_18524001_2 - 9.5e-05 22.1 0.2 0.00022 20.9 0.2 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Collagen PF01391.16 139713.5_18525001_2 - 4.6 6.9 119.5 1.6e+04 -50.4 119.5 3.7 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) zf-C2H2 PF00096.24 001274838.1_18524001_2 - 2.4e-21 74.8 49.0 0.00052 20.2 1.4 6.8 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001274838.1_18524001_2 - 1.8e-10 40.6 54.0 0.0074 16.9 0.8 7.2 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001274838.1_18524001_2 - 2.6e-09 37.0 36.0 0.00073 19.7 0.4 6.9 6 1 0 6 6 6 4 Zinc-finger double domain zf-AD PF07776.13 001274838.1_18524001_2 - 3.5e-08 33.4 5.9 3.5e-08 33.4 5.9 4.0 2 1 0 2 2 2 1 Zinc-finger associated domain (zf-AD) zf-met PF12874.5 001274838.1_18524001_2 - 0.0005 20.2 40.3 0.044 14.0 0.1 7.2 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001274838.1_18524001_2 - 0.00073 19.7 31.1 0.0059 16.8 0.1 6.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding HNH_5 PF14279.4 001274838.1_18524001_2 - 7.6 6.4 18.7 2.3 8.0 2.6 4.7 4 1 0 4 4 4 0 HNH endonuclease FDF PF09532.8 001274841.1_18526001_1 - 1.3e-36 125.5 15.0 4.7e-29 101.2 5.8 4.0 2 2 1 3 3 3 2 FDF domain LSM14 PF12701.5 001274841.1_18526001_1 - 2.9e-28 97.6 0.0 4.9e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.4 001274841.1_18526001_1 - 9.7e-06 25.5 0.0 2.8e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF4110 PF13422.4 001274841.1_18526001_1 - 0.013 15.4 1.6 3 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Chromo PF00385.22 001300221.1_18529001_1 - 1.8e-11 43.6 0.2 4.1e-11 42.5 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4838 PF16126.3 001300221.1_18529001_1 - 0.0064 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) SF3A2 PF16835.3 140346.2_18522001_2 - 3.9e-38 129.6 0.1 6.2e-38 128.9 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.5 140346.2_18522001_2 - 3.5e-06 27.1 1.9 3.5e-06 27.1 1.9 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.7 140346.2_18522001_2 - 0.0013 18.5 0.3 0.0025 17.6 0.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.9 140346.2_18522001_2 - 0.22 10.9 1.5 0.39 10.2 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like zf-C2H2_jaz PF12171.6 140346.2_18522001_2 - 4.9 7.4 6.2 8.6 6.7 4.7 2.3 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF1518 PF07469.10 144173.3_18521001_1 - 0.091 13.0 2.0 0.13 12.5 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) Pox_EPC_I2-L1 PF12575.6 144173.3_18521001_3 - 0.35 11.0 3.2 0.81 9.8 0.0 2.6 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 MADF_DNA_bdg PF10545.7 168979.4_18525001_2 - 4.2e-20 71.7 0.0 8.3e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.4 168979.4_18525001_2 - 0.00016 21.5 0.2 0.00032 20.6 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Bindin PF02084.13 168979.4_18525001_2 - 0.0074 16.5 0.1 0.016 15.3 0.1 1.5 1 0 0 1 1 1 1 Bindin HAUS-augmin3 PF14932.4 141157.4_18525001_3 - 0.0022 17.5 6.0 0.0022 17.5 6.0 1.5 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 DUF4763 PF15960.3 141157.4_18525001_3 - 0.13 11.4 6.1 0.3 10.2 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) IncA PF04156.12 141157.4_18525001_3 - 0.43 10.2 9.7 0.84 9.3 9.7 1.5 1 0 0 1 1 1 0 IncA protein IFP_35_N PF07334.11 141157.4_18525001_3 - 0.52 10.3 2.1 26 4.8 3.2 2.5 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GAS PF13851.4 141157.4_18525001_3 - 0.53 9.5 13.3 0.041 13.1 8.2 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.4 141157.4_18525001_3 - 0.71 9.0 6.6 1.3 8.2 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1640 PF07798.9 141157.4_18525001_3 - 0.71 9.8 10.1 1.3 8.9 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) PRKG1_interact PF15898.3 141157.4_18525001_3 - 1.6 9.6 16.3 0.27 12.0 11.6 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain HALZ PF02183.16 141157.4_18525001_3 - 8.3 6.6 8.1 2.3 8.4 2.8 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Swi5 PF07061.9 141157.4_18525001_3 - 9.1 6.3 7.2 9.4 6.2 2.4 2.8 3 0 0 3 3 3 0 Swi5 Maelstrom PF13017.4 176388.3_18524001_1 - 3.6e-85 284.9 0.1 6.9e-85 284.0 0.1 1.5 1 0 0 1 1 1 1 piRNA pathway germ-plasm component Nitr_red_alph_N PF14710.4 176388.3_18524001_1 - 1.4 9.3 3.7 9.9 6.6 0.4 2.7 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal DNA_pol_A_exo1 PF01612.18 001169964.2_18523001_3 - 0.082 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease Acyl_transf_3 PF01757.20 168093.3_18526001_2 - 1.6e-16 60.2 36.3 1.6e-16 60.2 36.3 2.0 3 0 0 3 3 3 1 Acyltransferase family DUF423 PF04241.13 168093.3_18526001_2 - 2.3 8.4 5.5 0.65 10.1 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF423) Pkinase PF00069.23 168986.2_18523001_2 - 3.4e-67 226.4 0.3 4.5e-67 226.1 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 168986.2_18523001_2 - 1.2e-19 70.5 0.1 1.6e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 168986.2_18523001_2 - 1.8e-08 34.5 0.3 3.9e-06 26.8 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.12 168986.2_18523001_2 - 0.0005 19.3 0.1 0.00081 18.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.18 168986.2_18523001_2 - 0.011 15.1 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase PAP2 PF01569.19 001300216.1_18525001_2 - 6.4e-28 97.1 6.1 1.4e-27 96.0 6.1 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.4 001300216.1_18525001_2 - 3e-05 23.7 5.9 7.4e-05 22.4 5.9 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.4 001300216.1_18525001_2 - 1.9 8.9 5.7 5 7.6 5.7 1.7 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Spt20 PF12090.6 139366.3_18526001_2 - 9.4 5.6 10.4 15 5.0 10.4 1.2 1 0 0 1 1 1 0 Spt20 family zf-C3HC4 PF00097.23 139366.3_18526001_3 - 4.3e-07 29.6 6.9 9.6e-07 28.4 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 139366.3_18526001_3 - 1.6e-06 27.8 5.3 3e-06 26.9 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 139366.3_18526001_3 - 1.7e-05 24.9 8.6 3.9e-05 23.7 8.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.4 139366.3_18526001_3 - 4.5e-05 23.2 5.3 0.00015 21.5 5.5 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.4 139366.3_18526001_3 - 6.3e-05 22.6 8.6 0.00069 19.3 8.1 2.5 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 139366.3_18526001_3 - 0.00024 20.9 6.3 0.00024 20.9 6.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 139366.3_18526001_3 - 0.027 14.5 6.5 0.095 12.7 6.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.4 139366.3_18526001_3 - 0.29 10.9 6.0 1.1 9.1 6.2 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_9 PF13901.4 140292.3_18524001_3 - 1.3e-66 224.3 23.3 3.7e-62 209.8 11.8 2.4 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon C1_1 PF00130.20 140292.3_18524001_3 - 2.4e-07 30.4 36.4 2.2e-06 27.3 11.3 4.0 3 1 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.14 140292.3_18524001_3 - 0.0079 16.4 5.0 0.0079 16.4 5.0 5.2 5 0 0 5 5 5 2 C1 domain zf-LITAF-like PF10601.7 167992.2_18523001_1 - 5.1e-23 81.0 11.1 5.1e-23 81.0 11.1 2.6 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain CBM_14 PF01607.22 167997.2_18521001_2 - 0.0003 20.8 3.4 0.00046 20.2 3.4 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Varsurf_PPLC PF03490.11 167998.3_18522001_2 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C RAMP4 PF06624.10 167998.3_18522001_3 - 2.7e-27 94.5 0.0 4.1e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1206 PF06724.9 167998.3_18522001_3 - 0.0053 16.7 0.2 0.0082 16.1 0.2 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) Ureidogly_lyase PF04115.10 167998.3_18522001_3 - 0.046 13.4 0.1 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 Ureidoglycolate lyase Trypsin PF00089.24 168001.2_18522001_1 - 3.1e-53 180.7 2.9 3.7e-53 180.5 2.9 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 168001.2_18522001_1 - 7.6e-06 26.7 0.9 1.1e-05 26.2 0.9 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 168001.2_18522001_1 - 0.0001 22.5 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DARPP-32 PF05395.10 168014.2_18523001_1 - 2.3 8.3 4.4 3.3 7.8 4.4 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 PID PF00640.21 168014.2_18523001_3 - 0.00056 19.8 0.1 0.0017 18.3 0.0 1.8 3 0 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.4 168014.2_18523001_3 - 0.00069 19.4 0.0 0.00088 19.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Tom5 PF10642.7 168032.2_18521001_1 - 0.081 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Trehalose_recp PF06151.11 168048.2_18523001_1 - 2e-183 609.6 12.6 2.2e-183 609.4 12.6 1.0 1 0 0 1 1 1 1 Trehalose receptor 7tm_7 PF08395.10 168048.2_18523001_1 - 1.2e-21 77.2 34.6 2.3e-21 76.3 34.6 1.4 1 1 0 1 1 1 1 7tm Chemosensory receptor CTP_transf_3 PF02348.17 168828.2_18522001_3 - 2e-20 73.6 0.0 2.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.5 168828.2_18522001_3 - 1.2e-05 25.6 0.0 1.5e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Attacin_C PF03769.13 168735.2_18521001_1 - 0.00091 19.3 0.3 0.0011 18.9 0.3 1.1 1 0 0 1 1 1 1 Attacin, C-terminal region 7tm_6 PF02949.18 206347.1_18523001_1 - 7.4e-37 127.0 20.7 9e-37 126.7 20.7 1.1 1 0 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.10 206347.1_18523001_1 - 5.9e-07 28.9 18.5 9.4e-07 28.2 18.5 1.2 1 0 0 1 1 1 1 7tm Chemosensory receptor Mt_ATP-synt_B PF05405.12 206347.1_18523001_1 - 0.05 13.1 0.3 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Aa_trans PF01490.16 168430.3_18524001_3 - 1.5e-56 191.7 33.2 1.8e-56 191.5 33.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MoaC PF01967.19 176316.2_18525001_2 - 2.7e-52 176.2 5.5 4.1e-52 175.6 5.5 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.11 176316.2_18525001_2 - 7.6e-40 135.7 0.0 1.3e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.19 176316.2_18525001_2 - 1.6e-31 109.8 0.2 2.7e-31 109.0 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.4 176316.2_18525001_2 - 6.9e-07 29.5 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.4 176316.2_18525001_2 - 0.0071 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain GntR PF00392.19 176316.2_18525001_2 - 0.014 14.9 0.0 0.034 13.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Peptidase_M17 PF00883.19 140137.3_18525001_1 - 2.2e-84 283.3 0.0 2.9e-84 282.9 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.15 140137.3_18525001_1 - 1.2e-24 86.4 0.1 2.1e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain SPT_ssu-like PF11779.6 140137.3_18525001_3 - 0.079 12.5 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Solute_trans_a PF03619.14 001299970.1_18526001_3 - 2.7e-92 308.9 18.3 3.5e-92 308.6 18.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Spectrin PF00435.19 206265.3_18529001_3 - 0 1447.7 338.8 8.8e-21 74.2 3.0 31.4 31 0 0 31 31 31 31 Spectrin repeat CH PF00307.29 206265.3_18529001_3 - 6.3e-48 161.4 2.3 8.7e-24 83.7 0.0 5.1 5 0 0 5 5 5 2 Calponin homology (CH) domain PH_9 PF15410.4 206265.3_18529001_3 - 5.2e-15 55.7 0.8 3e-14 53.3 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.27 206265.3_18529001_3 - 4e-10 40.0 0.0 1.2e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.4 206265.3_18529001_3 - 1.9e-07 30.7 0.0 5.8e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 206265.3_18529001_3 - 5.9e-05 22.5 0.0 0.0002 20.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 206265.3_18529001_3 - 9.8e-05 21.8 0.2 0.00024 20.5 0.2 1.7 1 0 0 1 1 1 1 SH3 domain CAMSAP_CH PF11971.6 206265.3_18529001_3 - 0.0006 19.5 0.0 0.25 11.1 0.0 3.3 2 0 0 2 2 2 1 CAMSAP CH domain SH3_3 PF08239.9 206265.3_18529001_3 - 0.071 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Spectrin PF00435.19 001202112.2_18529001_3 - 0 1450.3 338.8 8.3e-21 74.3 3.0 31.3 31 0 0 31 31 31 31 Spectrin repeat CH PF00307.29 001202112.2_18529001_3 - 5.4e-48 161.6 2.4 8.2e-24 83.8 0.0 5.2 5 0 0 5 5 5 2 Calponin homology (CH) domain PH_9 PF15410.4 001202112.2_18529001_3 - 5e-15 55.8 0.8 2.8e-14 53.4 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.27 001202112.2_18529001_3 - 3.6e-10 40.1 0.0 1.1e-09 38.6 0.0 1.9 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.4 001202112.2_18529001_3 - 1.7e-07 30.8 0.0 5.5e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 001202112.2_18529001_3 - 5.4e-05 22.7 0.0 0.00019 20.9 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001202112.2_18529001_3 - 9.1e-05 21.9 0.2 0.00022 20.6 0.2 1.7 1 0 0 1 1 1 1 SH3 domain CAMSAP_CH PF11971.6 001202112.2_18529001_3 - 0.0005 19.7 0.0 0.23 11.2 0.0 3.4 2 0 0 2 2 2 1 CAMSAP CH domain SH3_3 PF08239.9 001202112.2_18529001_3 - 0.066 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Spectrin PF00435.19 001274438.1_18529001_1 - 0 1448.8 338.8 8.6e-21 74.3 3.0 31.4 31 0 0 31 31 31 31 Spectrin repeat CH PF00307.29 001274438.1_18529001_1 - 5.6e-48 161.5 2.3 8.5e-24 83.7 0.0 5.1 5 0 0 5 5 5 2 Calponin homology (CH) domain PH_9 PF15410.4 001274438.1_18529001_1 - 4.8e-15 55.8 0.8 2.9e-14 53.3 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.27 001274438.1_18529001_1 - 3.8e-10 40.1 0.0 1.1e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.4 001274438.1_18529001_1 - 1.8e-07 30.7 0.0 5.7e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 001274438.1_18529001_1 - 5.7e-05 22.6 0.0 0.0002 20.9 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001274438.1_18529001_1 - 9.5e-05 21.8 0.2 0.00023 20.5 0.2 1.7 1 0 0 1 1 1 1 SH3 domain CAMSAP_CH PF11971.6 001274438.1_18529001_1 - 0.00056 19.6 0.0 0.24 11.1 0.0 3.3 2 0 0 2 2 2 1 CAMSAP CH domain SH3_3 PF08239.9 001274438.1_18529001_1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain RRM_1 PF00076.20 168261.3_18523001_1 - 0.0013 18.4 0.0 0.0085 15.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3388 PF11868.6 168261.3_18523001_1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) CDC37_M PF08565.9 057658.5_18524001_3 - 2.2e-25 88.8 1.3 2.2e-25 88.8 1.3 2.2 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.12 057658.5_18524001_3 - 2.1e-12 47.9 16.9 2.1e-12 47.9 16.9 3.3 2 1 2 4 4 4 1 Cdc37 N terminal kinase binding CDC37_C PF08564.8 057658.5_18524001_3 - 4.3e-12 45.9 0.1 4.3e-12 45.9 0.1 3.4 3 1 0 3 3 3 1 Cdc37 C terminal domain DUF641 PF04859.10 057658.5_18524001_3 - 5.3 7.3 12.2 0.072 13.3 3.2 2.5 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.4 057658.5_18524001_3 - 7.3 5.7 10.8 5.1 6.2 5.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.13 168233.3_18526001_3 - 1.7e-18 66.3 15.1 5e-18 64.8 15.1 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.19 168233.3_18526001_3 - 6.1e-05 22.9 11.9 6.1e-05 22.9 11.9 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.15 168233.3_18526001_3 - 0.0013 19.1 9.8 0.0013 19.1 9.8 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor CCDC92 PF14916.4 168233.3_18526001_3 - 0.011 15.3 0.4 0.024 14.3 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function NYD-SP28_assoc PF14775.4 168233.3_18526001_3 - 0.04 13.9 1.3 0.12 12.4 1.3 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain Peptidase_S51 PF03575.15 001274328.1_18527001_1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 LRR_4 PF12799.5 001274328.1_18527001_2 - 0.027 14.7 8.6 1.1 9.7 0.9 4.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001274328.1_18527001_2 - 0.33 10.6 14.4 1.1 9.0 3.1 3.7 3 0 0 3 3 3 0 Leucine rich repeat Arm PF00514.21 001274328.1_18527001_2 - 0.38 10.7 3.2 14 5.7 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat LRR_6 PF13516.4 001274328.1_18527001_2 - 3.1 7.9 11.4 0.39 10.8 0.5 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Spt20 PF12090.6 167895.2_18526001_2 - 9.3 5.7 10.4 14 5.1 10.4 1.1 1 0 0 1 1 1 0 Spt20 family zf-C3HC4 PF00097.23 167895.2_18526001_3 - 4e-07 29.6 6.9 9.2e-07 28.5 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 167895.2_18526001_3 - 1.5e-06 27.8 5.3 2.8e-06 26.9 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 167895.2_18526001_3 - 1.6e-05 24.9 8.6 3.8e-05 23.7 8.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.4 167895.2_18526001_3 - 5.2e-05 23.0 5.5 0.00018 21.3 5.7 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.4 167895.2_18526001_3 - 5.9e-05 22.7 8.7 0.00068 19.3 8.2 2.6 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 167895.2_18526001_3 - 0.00023 21.0 6.3 0.00023 21.0 6.3 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 167895.2_18526001_3 - 0.025 14.6 6.5 0.092 12.8 6.5 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.4 167895.2_18526001_3 - 0.34 10.7 6.3 1.3 8.8 6.5 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 ADK PF00406.20 168493.2_18523001_2 - 7.8e-44 149.3 0.0 1.1e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.4 168493.2_18523001_2 - 5.8e-34 117.3 0.0 1.1e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 168493.2_18523001_2 - 3.6e-07 30.3 0.0 2.3e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.4 168493.2_18523001_2 - 0.0042 17.5 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.15 168493.2_18523001_2 - 0.013 15.1 0.9 0.32 10.5 0.2 2.4 2 0 0 2 2 2 0 Thymidylate kinase Chitin_bind_4 PF00379.21 140626.2_18522001_3 - 1.5e-09 38.1 3.3 1.5e-09 38.1 3.3 2.3 3 0 0 3 3 3 1 Insect cuticle protein Pkinase PF00069.23 001014592.2_18525001_3 - 2.5e-71 240.0 0.3 3.8e-71 239.4 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001014592.2_18525001_3 - 8.6e-39 133.2 0.0 1.4e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.16 001014592.2_18525001_3 - 8.3e-36 121.9 4.3 3.3e-18 65.5 0.4 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.4 001014592.2_18525001_3 - 6e-10 38.8 0.0 8.9e-09 34.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like dsrm PF00035.24 001274497.1_18523001_3 - 4.8e-06 27.0 1.0 0.003 18.1 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif zf-C2H2 PF00096.24 001274458.1_18529001_2 - 3e-18 65.0 36.8 7.9e-06 25.9 0.6 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001274458.1_18529001_2 - 2.2e-14 52.8 31.0 0.00089 19.8 0.5 6.0 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001274458.1_18529001_2 - 6.9e-11 41.9 30.4 3.2e-06 27.2 0.2 5.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.4 001274458.1_18529001_2 - 0.0041 16.9 35.0 0.36 10.7 0.4 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001274458.1_18529001_2 - 0.0099 16.0 24.8 0.025 14.8 0.1 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001274458.1_18529001_2 - 0.011 16.0 0.2 0.011 16.0 0.2 5.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 001274458.1_18529001_2 - 0.59 9.8 30.7 0.76 9.5 6.0 5.1 5 0 0 5 5 5 0 zinc-finger C2H2-type DUF3915 PF13054.4 001274458.1_18529001_2 - 0.66 9.8 9.9 0.12 12.2 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) SCAI PF12070.6 001274534.2_18529001_2 - 3.7e-217 722.3 0.0 5.4e-217 721.7 0.0 1.2 1 0 0 1 1 1 1 Protein SCAI MAS20 PF02064.13 001274534.2_18529001_3 - 0.29 11.1 3.8 0.58 10.1 3.8 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor DUF4461 PF14688.4 139764.3_18524001_3 - 7.9e-116 387.0 0.0 1e-115 386.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.4 139764.3_18524001_3 - 5.2e-34 116.5 0.2 1.3e-33 115.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF1708 PF08101.9 139764.3_18524001_3 - 0.0056 15.7 5.1 0.15 11.0 1.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) EF-hand_2 PF09068.9 139764.3_18524001_3 - 0.0088 16.0 1.0 0.79 9.7 0.4 2.4 2 0 0 2 2 2 1 EF hand WD-3 PF09765.7 139764.3_18524001_3 - 0.047 12.9 0.2 0.047 12.9 0.2 2.5 3 0 0 3 3 3 0 WD-repeat region FAM176 PF14851.4 139786.3_18529001_2 - 0.17 11.4 1.2 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 FAM176 family Glycophorin_A PF01102.16 139786.3_18529001_3 - 0.67 10.1 3.1 0.39 10.8 0.1 2.2 2 0 0 2 2 2 0 Glycophorin A Cadherin_C_2 PF16492.3 139786.3_18529001_3 - 0.73 10.5 0.0 0.73 10.5 0.0 2.8 4 0 0 4 4 4 0 Cadherin cytoplasmic C-terminal SUR7 PF06687.10 001275076.1_18524001_3 - 8e-05 22.2 1.1 8e-05 22.2 1.1 1.6 2 0 0 2 2 2 1 SUR7/PalI family MTABC_N PF16185.3 001275076.1_18524001_3 - 0.28 10.5 5.4 0.6 9.5 5.4 1.5 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Claudin_2 PF13903.4 001275076.1_18524001_3 - 4.3 6.9 9.6 25 4.4 9.5 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NfeD PF01957.16 001275076.1_18524001_3 - 5.8 7.2 8.0 3.2 8.0 4.9 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding 7tm_6 PF02949.18 079399.3_18523001_1 - 6.5e-13 48.3 15.4 8.3e-13 48.0 15.4 1.1 1 0 0 1 1 1 1 7tm Odorant receptor DBR1 PF05011.11 001169835.1_18522001_3 - 0.064 13.5 1.6 2.5 8.4 0.7 2.1 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain DUF737 PF05300.9 001169835.1_18522001_3 - 0.12 12.6 4.6 0.23 11.7 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Trehalose_recp PF06151.11 001299963.1_18524001_1 - 2e-50 171.5 0.1 2.5e-50 171.2 0.1 1.0 1 0 0 1 1 1 1 Trehalose receptor YtpI PF14007.4 001299963.1_18524001_1 - 0.027 14.5 2.8 0.073 13.1 2.8 1.7 1 0 0 1 1 1 0 YtpI-like protein Trehalose_recp PF06151.11 001299963.1_18524001_3 - 3e-111 371.8 10.7 4e-111 371.4 10.7 1.1 1 0 0 1 1 1 1 Trehalose receptor 7tm_7 PF08395.10 001299963.1_18524001_3 - 1.1e-16 60.9 12.3 1.5e-16 60.4 12.3 1.2 1 0 0 1 1 1 1 7tm Chemosensory receptor HTH_Tnp_Tc5 PF03221.14 001274291.1_18524001_1 - 8.8e-12 44.8 2.0 7.2e-07 29.0 0.0 3.0 2 1 0 2 2 2 2 Tc5 transposase DNA-binding domain CENP-B_N PF04218.11 001274291.1_18524001_1 - 1.1e-07 31.2 0.0 2.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sperm_Ag_HE2 PF05324.11 001274296.1_18523001_1 - 0.041 14.1 0.2 0.11 12.8 0.2 1.7 1 0 0 1 1 1 0 Sperm antigen HE2 Cupin_8 PF13621.4 001274296.1_18523001_2 - 8.6e-42 143.5 0.0 1.3e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.10 001274296.1_18523001_2 - 1.4e-09 37.7 0.0 3.4e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.20 001274296.1_18523001_2 - 9.1e-05 22.8 0.0 0.0002 21.6 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.9 001274296.1_18523001_2 - 0.056 13.0 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Cupin domain zf-C2H2 PF00096.24 080044.4_18527001_1 - 3.1e-11 43.0 14.1 5.5e-05 23.3 1.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 080044.4_18527001_1 - 1.7e-07 31.4 12.8 0.005 17.4 1.4 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.5 080044.4_18527001_1 - 2.2e-05 24.5 5.7 0.094 13.0 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 080044.4_18527001_1 - 0.02 14.7 8.7 0.24 11.3 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CpXC PF14353.4 080044.4_18527001_1 - 0.036 14.0 8.9 0.058 13.3 1.4 2.7 2 1 1 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.8 080044.4_18527001_1 - 0.083 12.9 11.3 0.33 11.0 0.2 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.6 080044.4_18527001_1 - 0.2 11.9 11.7 0.49 10.6 2.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 080044.4_18527001_1 - 1.6 8.4 15.1 4 7.2 0.4 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.3 080044.4_18527001_1 - 4.1 7.2 5.1 15 5.4 0.1 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) XPA_N PF01286.16 080044.4_18527001_1 - 8.3 6.4 9.6 2 8.4 0.1 3.3 3 0 0 3 3 3 0 XPA protein N-terminal MFS_1 PF07690.14 001299965.1_18528001_2 - 1.3e-34 119.5 28.0 1.7e-23 83.0 11.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Fer4_5 PF12801.5 001299965.1_18528001_2 - 0.32 10.8 5.1 0.15 11.9 1.2 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain CENP-B_dimeris PF09026.8 001299965.1_18528001_2 - 0.48 10.7 7.1 0.57 10.5 1.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CbtA PF09490.8 001299965.1_18528001_2 - 1 8.9 5.9 2.7 7.6 5.9 1.7 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF733 PF05306.9 140378.3_18522001_1 - 1.4e-23 82.8 1.3 1.4e-23 82.8 1.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF733) I-set PF07679.14 001274746.1_18526001_2 - 6.6e-21 74.1 0.0 7.2e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.4 001274746.1_18526001_2 - 7.2e-19 68.1 0.4 7.9e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001274746.1_18526001_2 - 8.6e-18 64.4 2.9 2.3e-09 37.3 0.4 2.8 3 0 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.23 001274746.1_18526001_2 - 1.1e-16 60.7 0.4 1.3e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 001274746.1_18526001_2 - 4.8e-12 45.9 0.2 1.7e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Receptor_2B4 PF11465.6 001274746.1_18526001_2 - 0.06 13.4 0.1 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 LAMTOR PF15454.4 001202207.2_18522001_3 - 1.1e-20 73.9 0.8 1.9e-20 73.1 0.8 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator HpaB_N PF11794.6 001202207.2_18522001_3 - 0.028 13.9 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Destabilase PF05497.10 168186.3_18525001_2 - 6e-31 107.1 0.7 1.2e-30 106.1 0.7 1.5 1 0 0 1 1 1 1 Destabilase FERM_M PF00373.16 139601.4_18527001_1 - 4.8e-42 142.9 0.0 8e-42 142.3 0.0 1.4 1 0 0 1 1 1 1 FERM central domain PH PF00169.27 139601.4_18527001_1 - 8e-08 32.6 0.0 2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PH domain MAP7 PF05672.9 001274473.1_18529001_1 - 1.7e-20 73.2 75.5 1.7e-20 73.2 75.5 4.3 4 0 0 4 4 4 1 MAP7 (E-MAP-115) family MAP7 PF05672.9 001300004.1_18529001_1 - 2e-20 73.0 75.5 2e-20 73.0 75.5 3.5 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family Trypsin PF00089.24 001274479.1_18528001_2 - 6.1e-59 199.4 0.6 6.1e-59 199.4 0.6 2.0 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.4 001274479.1_18528001_2 - 5.8e-06 27.1 0.1 2e-05 25.4 0.1 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain Chitin_bind_4 PF00379.21 139617.2_18522001_1 - 1.5e-13 50.9 2.1 2.3e-13 50.3 2.1 1.3 1 0 0 1 1 1 1 Insect cuticle protein DUF3439 PF11921.6 168072.2_18529001_1 - 0.22 11.4 1.0 0.41 10.5 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.30 168072.2_18529001_2 - 6.3e-46 153.3 36.2 2.9e-07 30.9 0.3 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.5 168072.2_18529001_2 - 2.4e-12 46.4 2.8 4.6e-12 45.5 2.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 168072.2_18529001_2 - 2.4e-11 43.1 1.8 2e-10 40.2 2.7 2.1 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.5 168072.2_18529001_2 - 2.4e-11 43.6 7.2 0.66 10.2 0.0 7.0 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 168072.2_18529001_2 - 9e-09 34.3 13.6 0.27 9.7 0.1 6.3 3 2 3 6 6 6 6 Nucleoporin Nup120/160 EF-hand_7 PF13499.4 001202116.1_18526001_1 - 9e-24 83.6 2.2 5.9e-12 45.8 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001202116.1_18526001_1 - 3.1e-22 76.3 3.4 2.4e-07 29.7 0.3 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.4 001202116.1_18526001_1 - 9.3e-20 68.7 2.8 3.3e-07 29.6 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.4 001202116.1_18526001_1 - 2.9e-18 64.3 3.5 3.7e-06 26.1 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.4 001202116.1_18526001_1 - 7e-17 60.8 5.8 4.3e-10 39.1 0.1 4.3 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001202116.1_18526001_1 - 6e-05 23.2 0.2 0.031 14.5 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001202116.1_18526001_1 - 0.0022 17.8 1.1 0.0041 16.9 0.2 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001202116.1_18526001_1 - 0.0022 18.1 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.4 001202116.1_18526001_1 - 0.0035 17.0 1.4 0.025 14.3 0.0 2.6 2 1 1 3 3 3 1 EF hand DUF733 PF05306.9 139668.4_18522001_2 - 1.8e-23 82.5 1.6 2.5e-23 82.0 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF733) SRPRB PF09439.8 139668.4_18522001_2 - 0.04 13.2 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Transformer PF06495.9 079390.3_18522001_2 - 7.1e-51 172.8 81.4 2.4e-50 171.1 81.4 1.7 1 1 0 1 1 1 1 Fruit fly transformer protein SOBP PF15279.4 079390.3_18522001_2 - 1.5 9.1 13.2 2 8.8 13.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MIP-T3 PF10243.7 079390.3_18522001_2 - 3.4 6.2 31.1 4.2 5.8 31.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF725 PF05267.10 139465.2_18522001_3 - 8.5e-33 112.8 5.8 1.4e-32 112.1 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF725) Mucin PF01456.15 139465.2_18522001_3 - 0.0022 17.9 14.9 0.004 17.0 14.9 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Vps8 PF12816.5 139465.2_18522001_3 - 0.01 15.2 0.1 0.013 14.9 0.1 1.1 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 DUF3439 PF11921.6 139465.2_18522001_3 - 0.031 14.1 7.2 0.062 13.1 7.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Helicase_C PF00271.29 001276240.1_18523001_1 - 8.2e-25 87.2 0.1 1.7e-24 86.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.27 001276240.1_18523001_1 - 6.6e-17 61.7 0.0 9.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase tRNA-synt_1b PF00579.23 001276240.1_18523001_1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) PLA2G12 PF06951.9 001144485.3_18523001_1 - 3.8e-48 163.7 7.6 5.3e-48 163.2 7.6 1.1 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) KASH PF10541.7 001274282.2_18529001_3 - 9.6e-20 70.5 2.2 2.4e-19 69.2 2.2 1.7 1 0 0 1 1 1 1 Nuclear envelope localisation domain Med30 PF11315.6 138202.4_18523001_2 - 6.7e-47 159.3 1.0 6.7e-47 159.3 1.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 30 NEMO PF11577.6 138202.4_18523001_2 - 0.0019 18.1 0.4 0.0055 16.6 0.4 1.7 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO DRMBL PF07522.12 138202.4_18523001_2 - 0.0075 16.4 0.9 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Sigma70_ner PF04546.11 138202.4_18523001_2 - 0.011 15.5 0.5 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region EB PF01683.16 001274888.1_18529001_3 - 0.0047 17.0 14.6 0.19 11.9 14.6 2.7 1 1 0 1 1 1 1 EB module Ribosomal_L15e PF00827.15 001258468.1_18522001_1 - 5e-91 303.5 7.5 6.1e-91 303.2 7.5 1.1 1 0 0 1 1 1 1 Ribosomal L15 Vinculin PF01044.17 079495.3_18526001_1 - 0 1040.9 41.1 1.5e-213 711.8 21.7 2.1 1 1 1 2 2 2 2 Vinculin family Rotamase PF00639.19 079495.3_18526001_1 - 0.0087 16.9 0.4 0.44 11.4 0.0 3.7 2 1 1 3 3 3 1 PPIC-type PPIASE domain Spectrin PF00435.19 079495.3_18526001_1 - 1.2 9.6 6.2 1 9.8 0.3 3.8 4 0 0 4 4 4 0 Spectrin repeat PEP-utilisers_N PF05524.11 079495.3_18526001_1 - 2.1 8.4 5.9 1.2 9.2 0.3 3.4 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal 4F5 PF04419.12 001274964.1_18522001_3 - 1.5e-09 38.4 13.6 2.6e-09 37.7 13.6 1.4 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.5 001274964.1_18522001_3 - 0.01 16.1 0.8 0.017 15.4 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF629 PF04780.10 001274964.1_18522001_3 - 0.015 13.8 0.4 0.017 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-met2 PF12907.5 001274964.1_18522001_3 - 4.9 7.2 8.8 0.74 9.9 3.9 2.2 2 1 0 2 2 2 0 Zinc-binding GWT1 PF06423.10 139397.3_18524001_3 - 1.3e-30 106.4 1.6 1.3e-30 106.4 1.6 2.2 2 1 1 3 3 3 1 GWT1 DUF3493 PF11998.6 139397.3_18524001_3 - 1.5 8.9 3.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) PHtD_u1 PF16645.3 001274272.1_18523001_1 - 0.08 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein PTN_MK_C PF01091.16 001274272.1_18523001_3 - 4.2e-19 68.6 17.5 8.3e-12 45.2 5.4 2.7 1 1 1 2 2 2 2 PTN/MK heparin-binding protein family, C-terminal domain Chitin_bind_4 PF00379.21 144405.2_18522001_1 - 5.9e-17 61.8 1.7 8.2e-17 61.3 1.7 1.2 1 0 0 1 1 1 1 Insect cuticle protein LVIVD PF08309.9 144405.2_18522001_1 - 0.73 9.1 0.0 0.73 9.1 0.0 2.3 3 0 0 3 3 3 0 LVIVD repeat DUF86 PF01934.15 001300178.1_18529001_2 - 0.12 12.2 0.6 0.32 10.7 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF86 DUF3225 PF11533.6 001300178.1_18529001_3 - 0.025 14.2 0.5 0.048 13.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) Ribosomal_S5_C PF03719.13 001043187.2_18523001_3 - 6.5e-22 76.7 0.0 1.1e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.18 001043187.2_18523001_3 - 3.4e-15 55.6 0.6 7.9e-15 54.5 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain MOR2-PAG1_N PF14222.4 001274709.1_18529001_2 - 2.6e-165 551.4 6.9 2.9e-165 551.2 2.8 2.2 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.4 001274709.1_18529001_2 - 3.2e-74 249.9 2.8 3.2e-74 249.9 2.8 3.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.4 001274709.1_18529001_2 - 6.5e-39 133.3 13.2 7.7e-09 33.7 0.1 5.1 5 0 0 5 5 5 5 Cell morphogenesis central region Spt20 PF12090.6 001274709.1_18529001_2 - 0.001 18.6 11.9 0.001 18.6 11.9 4.6 4 0 0 4 4 4 1 Spt20 family HEAT_2 PF13646.4 001274709.1_18529001_2 - 0.042 14.1 0.3 0.24 11.7 0.3 2.4 1 0 0 1 1 1 0 HEAT repeats Caerin_1 PF07440.10 001274709.1_18529001_2 - 0.1 12.6 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Caerin 1 protein IMD PF08397.9 001300098.1_18527001_2 - 1.2e-34 119.5 7.4 2.2e-34 118.6 7.4 1.5 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_1 PF00018.26 001300098.1_18527001_2 - 2.9e-10 39.5 0.0 5.4e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 001300098.1_18527001_2 - 9.4e-08 31.7 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.3 001300098.1_18527001_2 - 1.4e-06 28.0 7.9 2.3e-06 27.3 7.9 1.3 1 0 0 1 1 1 1 BAR domain of APPL family SH3_2 PF07653.15 001300098.1_18527001_2 - 8.2e-05 22.1 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.16 001300098.1_18527001_2 - 8.4e-05 22.2 7.3 0.00015 21.4 7.3 1.3 1 0 0 1 1 1 1 BAR domain DNA_pol_phi PF04931.11 001169870.1_18522001_3 - 0.38 8.7 11.0 0.49 8.3 11.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi RPEL PF02755.13 001202114.1_18525001_3 - 1.2e-25 88.3 11.2 5.9e-09 35.2 0.8 3.7 3 0 0 3 3 3 3 RPEL repeat zf-LITAF-like PF10601.7 001299998.1_18523001_1 - 6.3e-23 80.7 11.1 6.3e-23 80.7 11.1 3.5 3 0 0 3 3 3 2 LITAF-like zinc ribbon domain Xylo_C PF12529.6 139448.4_18527001_2 - 2.3e-52 177.1 0.0 3.9e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.19 139448.4_18527001_2 - 1.9e-47 161.7 0.0 2.7e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme WSC PF01822.17 139448.4_18527001_2 - 7.4e-20 70.8 6.7 7.4e-20 70.8 6.7 1.8 2 0 0 2 2 2 1 WSC domain zf-C3HC4_3 PF13920.4 167916.3_18528001_2 - 0.17 11.6 3.5 0.61 9.9 3.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Codanin-1_C PF15296.4 167916.3_18528001_3 - 4.8e-34 117.0 2.8 4.8e-34 117.0 2.8 3.1 4 0 0 4 4 4 1 Codanin-1 C-terminus DUF3677 PF12432.6 167916.3_18528001_3 - 0.99 9.6 4.0 4.8 7.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) Ank_2 PF12796.5 001274275.1_18525001_3 - 1.7e-30 105.3 1.1 5.6e-13 49.2 0.2 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.28 001274275.1_18525001_3 - 2.8e-20 71.7 0.6 3.1e-06 27.3 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.4 001274275.1_18525001_3 - 1.9e-17 63.2 5.3 1e-07 32.2 0.3 3.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.4 001274275.1_18525001_3 - 3e-16 59.1 0.2 7.1e-06 26.1 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.4 001274275.1_18525001_3 - 5.2e-16 57.0 1.3 0.0016 18.7 0.1 4.2 3 0 0 3 3 3 3 Ankyrin repeat Lipocalin_5 PF13924.4 001274275.1_18525001_3 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipocalin-like domain Pro-NT_NN PF07421.9 001274275.1_18525001_3 - 1.2 9.3 6.7 0.85 9.7 2.3 2.3 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor DUF3461 PF11944.6 001274275.1_18525001_3 - 2 8.4 7.6 0.3 11.1 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) DUF4535 PF15054.4 001275295.1_18521001_1 - 3.5e-18 64.9 0.9 8.5e-18 63.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4535) INCENP_N PF12178.6 001275295.1_18521001_1 - 0.11 12.3 0.2 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal RIX1 PF08167.10 206425.3_18525001_1 - 8.7e-07 28.7 1.9 2.3e-06 27.4 1.1 2.2 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis CNOT1_TTP_bind PF16417.3 206425.3_18525001_1 - 0.003 16.6 1.0 0.14 11.1 0.0 3.4 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain PI-PLC-Y PF00387.17 206425.3_18525001_1 - 0.021 15.1 0.4 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, Y domain ACP53EA PF06313.9 206425.3_18525001_1 - 0.13 12.4 5.8 1.6 8.8 0.1 3.3 4 0 0 4 4 4 0 Drosophila ACP53EA protein GAGA PF09237.9 206356.3_18529001_3 - 3.7e-34 116.2 3.1 1.2e-33 114.6 3.1 2.0 1 0 0 1 1 1 1 GAGA factor BTB PF00651.29 206356.3_18529001_3 - 3.2e-21 75.5 0.0 7.7e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain FYDLN_acid PF09538.8 206356.3_18529001_3 - 0.23 12.0 2.8 2.4 8.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Attacin_C PF03769.13 001274757.1_18522001_3 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 Attacin, C-terminal region FH2 PF02181.21 001014571.1_18529001_1 - 2.1e-80 270.5 1.1 3.5e-80 269.8 1.1 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.14 001014571.1_18529001_1 - 1.9e-21 76.5 0.1 5.7e-21 74.9 0.1 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.11 001014571.1_18529001_1 - 0.0001 21.8 0.0 0.00032 20.2 0.0 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain IBB PF01749.18 001014571.1_18529001_1 - 0.00014 22.0 1.2 0.00014 22.0 1.2 3.7 3 0 0 3 3 3 1 Importin beta binding domain DUF1091 PF06477.11 001031971.1_18522001_1 - 1.7e-15 57.1 0.0 2.8e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1091) Axin_b-cat_bind PF08833.8 001031971.1_18522001_2 - 6.1 6.9 8.6 13 5.9 8.6 1.5 1 0 0 1 1 1 0 Axin beta-catenin binding domain E1_dh PF00676.18 001031930.2_18528001_2 - 8.4e-69 231.7 0.7 1.5e-68 230.8 0.0 1.7 2 0 0 2 2 2 1 Dehydrogenase E1 component Transket_pyr PF02779.22 001031930.2_18528001_2 - 6.4e-59 198.5 0.0 1.1e-58 197.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.3 001031930.2_18528001_2 - 1.3e-53 180.6 0.0 2.3e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.3 001031930.2_18528001_2 - 7.9e-15 54.0 2.0 1.6e-14 53.0 2.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus DUF1091 PF06477.11 001031968.1_18521001_1 - 3.4e-12 46.5 3.6 1.6e-11 44.4 1.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1091) PACT_coil_coil PF10495.7 001274934.1_18529001_1 - 2.6e-16 59.8 1.1 2.6e-16 59.8 1.1 4.9 3 0 0 3 3 3 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein L27_N PF09060.8 001038897.1_18524001_1 - 0.06 13.3 1.1 0.2 11.6 0.1 2.3 2 0 0 2 2 2 0 L27_N Lig_chan PF00060.24 001038897.1_18524001_1 - 0.41 10.4 2.4 0.8 9.4 0.0 2.2 1 1 1 2 2 2 0 Ligand-gated ion channel Sugar_tr PF00083.22 001202150.1_18523001_1 - 3.2e-21 75.6 19.7 4.5e-21 75.1 19.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001202150.1_18523001_1 - 8.8e-05 21.5 40.5 0.0036 16.1 15.9 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily RRM_1 PF00076.20 001202164.2_18525001_2 - 2.3e-24 84.8 0.3 3.2e-17 62.0 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001202164.2_18525001_2 - 0.022 14.3 0.0 9.1 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.4 001144404.2_18529001_1 - 1.8e-08 34.4 30.2 0.33 11.8 0.7 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-Di19 PF05605.10 001144404.2_18529001_1 - 0.00095 19.3 2.8 0.00095 19.3 2.8 4.8 4 1 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.24 001144404.2_18529001_1 - 0.14 12.5 32.4 4.1 7.9 1.0 7.3 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-BED PF02892.13 001144404.2_18529001_1 - 3.6 7.6 7.3 14 5.7 0.0 3.4 3 0 0 3 3 3 0 BED zinc finger DUF4604 PF15377.4 001144404.2_18529001_2 - 3.2e-17 63.4 26.4 1.9e-15 57.7 26.4 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) I-set PF07679.14 001300035.1_18529001_2 - 2.7e-110 360.5 0.0 1e-16 60.6 0.0 10.4 10 0 0 10 10 10 9 Immunoglobulin I-set domain Ig_3 PF13927.4 001300035.1_18529001_2 - 1.5e-109 358.6 5.7 5.4e-13 49.2 0.1 11.1 10 0 0 10 10 10 9 Immunoglobulin domain Ig_2 PF13895.4 001300035.1_18529001_2 - 2e-84 277.9 1.0 2.2e-08 34.2 0.0 11.1 9 1 1 10 10 10 9 Immunoglobulin domain fn3 PF00041.19 001300035.1_18529001_2 - 1.2e-75 249.8 5.2 5.3e-14 52.2 0.9 7.5 7 0 0 7 7 7 6 Fibronectin type III domain ig PF00047.23 001300035.1_18529001_2 - 2.1e-63 210.4 5.9 2.3e-09 37.1 0.0 11.2 11 0 0 11 11 10 9 Immunoglobulin domain V-set PF07686.15 001300035.1_18529001_2 - 8.7e-34 115.8 23.4 1e-05 25.5 0.1 15.2 10 4 5 15 15 14 9 Immunoglobulin V-set domain C2-set_2 PF08205.10 001300035.1_18529001_2 - 2.8e-16 59.2 7.4 0.049 13.6 0.0 9.5 9 0 0 9 9 9 5 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001300035.1_18529001_2 - 2e-15 56.8 0.3 0.013 15.8 0.0 9.1 10 1 0 10 10 9 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001300035.1_18529001_2 - 1e-09 38.7 10.8 0.01 16.2 0.0 7.8 8 1 0 8 8 7 2 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.3 001300035.1_18529001_2 - 2e-06 27.7 0.1 0.0033 17.4 0.0 3.9 4 0 0 4 4 4 1 Fibronectin type III domain Izumo-Ig PF16706.3 001300035.1_18529001_2 - 1.2e-05 25.1 0.0 42 4.2 0.0 7.4 8 0 0 8 8 8 0 Izumo-like Immunoglobulin domain Spore_YhcN_YlaJ PF09580.8 001300035.1_18529001_2 - 0.0087 16.0 0.3 0.02 14.8 0.1 1.7 1 1 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) CorA PF01544.16 001274720.1_18526001_1 - 0.54 9.4 7.7 1.8 7.7 1.7 2.4 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein CALCOCO1 PF07888.9 001274567.1_18529001_1 - 0.64 8.4 34.9 0.24 9.8 13.8 3.3 3 0 0 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.13 001274567.1_18529001_1 - 7.4 6.8 39.4 1.6 9.0 1.1 4.0 4 0 0 4 4 4 0 Fez1 HECT PF00632.23 001144492.2_18529001_3 - 9e-100 334.0 0.0 1.3e-99 333.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.24 001144492.2_18529001_3 - 5.5e-38 128.5 10.7 1.8e-13 50.0 1.4 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.28 001144492.2_18529001_3 - 4.4e-22 78.2 0.1 1e-21 77.0 0.1 1.6 1 0 0 1 1 1 1 C2 domain Spt20 PF12090.6 001144492.2_18529001_3 - 3.9 6.9 10.4 11 5.4 10.4 1.7 1 0 0 1 1 1 0 Spt20 family DUF1074 PF06382.9 001299982.1_18522001_1 - 3.7e-07 30.3 14.3 0.00016 21.8 8.7 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1074) HMG_box PF00505.17 001299982.1_18522001_1 - 0.029 14.6 9.9 0.48 10.7 0.9 2.8 2 2 0 2 2 2 0 HMG (high mobility group) box SOSSC PF15925.3 001144500.2_18523001_1 - 5.1e-25 88.6 0.2 9.3e-25 87.7 0.2 1.4 1 0 0 1 1 1 1 SOSS complex subunit C CRF PF00473.15 001144500.2_18523001_1 - 0.098 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Corticotropin-releasing factor family MTS PF05175.12 001144500.2_18523001_3 - 2.6e-11 43.2 0.0 3.8e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.11 001144500.2_18523001_3 - 6.6e-08 32.1 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.13 001144500.2_18523001_3 - 2.9e-06 26.9 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.4 001144500.2_18523001_3 - 2.5e-05 24.8 0.0 5.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001144500.2_18523001_3 - 0.00024 20.8 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.14 001144500.2_18523001_3 - 0.0017 17.5 0.0 0.0037 16.4 0.0 1.5 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.10 001144500.2_18523001_3 - 0.0048 17.4 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001144500.2_18523001_3 - 0.026 15.1 0.0 0.062 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.16 001144500.2_18523001_3 - 0.035 13.6 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ank_2 PF12796.5 001274607.1_18529001_1 - 3.8e-143 466.3 49.9 1.1e-16 61.0 1.3 11.8 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.28 001274607.1_18529001_1 - 5.4e-130 418.6 68.8 1.3e-07 31.6 0.0 23.9 24 0 0 24 24 24 22 Ankyrin repeat Ank_4 PF13637.4 001274607.1_18529001_1 - 1.5e-127 414.4 78.3 6.5e-12 45.6 1.2 17.4 3 3 20 23 23 23 21 Ankyrin repeats (many copies) Ank_5 PF13857.4 001274607.1_18529001_1 - 4.3e-111 360.9 53.4 7.7e-13 48.3 0.1 17.2 3 3 15 20 20 20 19 Ankyrin repeats (many copies) Ank_3 PF13606.4 001274607.1_18529001_1 - 2.1e-109 343.9 45.9 4.8e-06 26.4 0.0 24.4 24 0 0 24 24 24 20 Ankyrin repeat ZU5 PF00791.18 001274607.1_18529001_1 - 2.5e-27 94.9 0.4 3e-26 91.5 0.1 2.5 2 0 0 2 2 2 1 ZU5 domain PK_C PF02887.14 001274607.1_18529001_1 - 0.00039 20.5 0.2 4.3 7.5 0.0 4.2 4 1 1 5 5 5 2 Pyruvate kinase, alpha/beta domain Ig_3 PF13927.4 001275303.1_18529001_3 - 6.7e-49 164.3 29.1 7.3e-11 42.4 0.8 9.9 9 0 0 9 9 9 9 Immunoglobulin domain Ig_2 PF13895.4 001275303.1_18529001_3 - 9.9e-41 137.8 20.3 1.1e-06 28.8 0.2 10.1 9 0 0 9 9 9 8 Immunoglobulin domain I-set PF07679.14 001275303.1_18529001_3 - 1.9e-33 114.2 12.6 6.5e-08 32.4 0.1 9.6 9 0 0 9 9 9 7 Immunoglobulin I-set domain ig PF00047.23 001275303.1_18529001_3 - 7.1e-24 83.7 16.8 0.00015 21.7 0.2 9.7 9 0 0 9 9 9 6 Immunoglobulin domain C2-set_2 PF08205.10 001275303.1_18529001_3 - 6.1e-22 77.4 5.3 2.3e-10 40.3 0.1 5.4 6 0 0 6 6 5 2 CD80-like C2-set immunoglobulin domain V-set PF07686.15 001275303.1_18529001_3 - 6.6e-18 64.7 9.1 2.1e-06 27.7 0.0 8.4 7 1 0 7 7 7 3 Immunoglobulin V-set domain C1-set PF07654.13 001275303.1_18529001_3 - 1.7e-12 47.5 16.4 1.5e-05 25.2 0.0 8.0 8 0 0 8 8 8 3 Immunoglobulin C1-set domain Receptor_2B4 PF11465.6 001275303.1_18529001_3 - 0.0015 18.6 0.2 0.038 14.1 0.1 2.9 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 TMEM154 PF15102.4 001275303.1_18529001_3 - 0.0027 17.5 0.0 0.0084 15.9 0.0 1.8 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.4 001275303.1_18529001_3 - 0.0048 17.6 0.0 0.019 15.6 0.0 2.0 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.4 001275303.1_18529001_3 - 0.0062 16.9 0.0 0.03 14.6 0.0 2.2 1 0 0 1 1 1 1 SCIMP protein Izumo-Ig PF16706.3 001275303.1_18529001_3 - 0.02 14.8 0.1 1.1 9.3 0.0 3.3 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Vpu PF00558.17 001275303.1_18529001_3 - 0.055 13.1 0.3 0.19 11.4 0.3 1.9 1 0 0 1 1 1 0 Vpu protein SIT PF15330.4 001275303.1_18529001_3 - 0.096 13.0 0.0 0.096 13.0 0.0 2.5 3 0 0 3 3 1 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM52 PF14979.4 001275303.1_18529001_3 - 0.74 9.6 4.2 2.2 8.1 4.2 1.7 1 0 0 1 1 1 0 Transmembrane 52 RRM_7 PF16367.3 001274679.1_18529001_2 - 5.9e-35 119.1 0.0 2.1e-33 114.2 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.3 001274679.1_18529001_2 - 9.3e-20 70.5 6.7 9.3e-20 70.5 6.7 2.2 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.20 001274679.1_18529001_2 - 8.1e-11 41.5 0.0 3e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.11 001274679.1_18529001_2 - 0.0096 15.8 8.7 0.015 15.2 8.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-O PF09496.8 001274679.1_18529001_2 - 0.038 13.8 0.5 0.075 12.9 0.5 1.4 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component RhoGEF PF00621.18 001347801.1_18529001_1 - 3.8e-43 147.7 5.3 7.4e-43 146.8 5.3 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.27 001347801.1_18529001_1 - 1.1e-17 64.3 0.5 2.2e-12 47.3 0.0 3.1 2 0 0 2 2 2 2 PH domain RBD PF02196.13 001347801.1_18529001_1 - 1.1e-14 54.2 0.1 1.2e-13 50.8 0.0 2.5 2 0 0 2 2 2 1 Raf-like Ras-binding domain PH_9 PF15410.4 001347801.1_18529001_1 - 1.2e-08 35.2 0.0 3.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain WH1 PF00568.21 001347801.1_18529001_1 - 0.001 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 WH1 domain PDZ PF00595.22 001347801.1_18529001_1 - 0.0081 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF1041 PF06292.15 001347801.1_18529001_1 - 0.21 11.8 2.5 6.1 7.1 0.4 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) SUIM_assoc PF16619.3 001347801.1_18529001_1 - 5.5 7.0 27.8 15 5.6 4.0 4.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF3677 PF12432.6 001347801.1_18529001_3 - 0.016 15.3 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Atrophin-1 PF03154.13 133140.1_18522120_3 - 1.9 6.5 5.2 2.7 6.0 5.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family PT PF04886.10 124740.2_18523120_1 - 0.2 11.1 8.9 0.54 9.7 8.9 1.6 1 0 0 1 1 1 0 PT repeat TMEM206 PF15122.4 124742.1_18521120_3 - 0.067 12.2 0.1 0.088 11.8 0.1 1.1 1 0 0 1 1 1 0 TMEM206 protein family TMIE PF16038.3 124742.1_18521120_3 - 0.16 11.7 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 TMIE protein DUF1196 PF06709.9 073905.1_18526120_2 - 0.11 12.6 0.4 0.25 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1196) DUF1505 PF07403.9 124746.1_18521120_1 - 5.6 7.0 7.5 2.7 8.0 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1505) Orthopox_B11R PF07033.9 073906.1_18521120_2 - 0.011 15.3 0.6 0.073 12.7 0.0 2.0 1 1 1 2 2 2 0 Orthopoxvirus B11R protein Val_tRNA-synt_C PF10458.7 073906.1_18521120_2 - 0.31 11.2 3.5 4.9 7.4 0.1 2.1 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Co_AT_N PF12557.6 073906.1_18521120_2 - 1.8 8.5 6.6 0.81 9.6 0.5 2.4 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal Orthopox_B11R PF07033.9 073907.1_18521120_3 - 0.018 14.7 0.6 0.11 12.1 0.0 2.0 1 1 1 2 2 2 0 Orthopoxvirus B11R protein Co_AT_N PF12557.6 073907.1_18521120_3 - 5.2 7.0 7.6 1.1 9.2 0.5 2.4 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal CPSF_A PF03178.13 124748.1_18526120_2 - 2.9e-100 335.6 0.0 5e-100 334.8 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.7 124748.1_18526120_2 - 7.2e-19 67.6 0.0 1e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term ANAPC4_WD40 PF12894.5 124748.1_18526120_2 - 0.088 13.0 0.0 9.4 6.5 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.13 124750.1_18525120_3 - 9.7e-101 337.2 0.0 4.5e-100 335.0 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.5 124750.1_18525120_3 - 0.08 13.1 0.0 8.7 6.6 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Agouti PF05039.10 124759.1_18522120_1 - 0.035 14.7 0.6 0.061 13.9 0.6 1.4 1 0 0 1 1 1 0 Agouti protein OTT_1508_deam PF14441.4 124767.1_18521120_1 - 0.46 10.3 6.9 0.76 9.6 1.1 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase GEP5 PF17053.3 124767.1_18521120_3 - 0.16 11.6 0.9 0.19 11.4 0.9 1.1 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 Kunitz_BPTI PF00014.21 073911.1_18521120_1 - 7.5e-05 22.8 6.4 9.3e-05 22.5 6.4 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain PSGP PF07276.9 124777.1_18522120_1 - 0.14 12.4 0.7 0.33 11.3 0.7 1.6 1 0 0 1 1 1 0 Apopolysialoglycoprotein (PSGP) Med6 PF04934.12 048229.1_18522120_1 - 0.0077 15.9 0.0 0.0099 15.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component PMR5N PF14416.4 048229.1_18522120_1 - 0.028 14.6 0.3 0.067 13.4 0.3 1.6 1 0 0 1 1 1 0 PMR5 N terminal Domain PRIMA1 PF16101.3 048230.1_18523120_2 - 0.88 9.5 4.7 2.2 8.2 4.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3703 PF12487.6 124810.1_18521120_3 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) DUF4033 PF13225.4 124812.1_18522120_2 - 0.055 13.3 0.4 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) ACCA PF03255.12 124815.1_18521120_1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DEC-1_N PF04625.11 133188.1_18521120_2 - 1.6 7.5 8.2 1.9 7.2 8.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2681 PF10883.6 124849.1_18522120_3 - 0.8 10.0 7.6 1.4 9.2 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) F-box PF00646.31 073923.1_18522120_3 - 2e-06 27.4 0.8 3.7e-06 26.5 0.8 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 073923.1_18522120_3 - 2.8e-05 23.8 0.2 6.1e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like RP-C PF03428.11 124882.2_18522120_2 - 0.12 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain Adeno_PV PF03910.11 124893.1_18521120_1 - 5.2 5.5 10.0 6.4 5.2 10.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Adeno_PV PF03910.11 124894.1_18521120_3 - 4.8 5.6 10.0 5.8 5.4 10.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF2717 PF10911.6 124903.1_18521120_1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) R3H PF01424.20 124912.1_18522120_1 - 0.057 13.3 0.5 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 R3H domain GBV-C_env PF12786.5 124913.1_18521120_2 - 0.12 10.9 0.6 0.15 10.6 0.6 1.1 1 0 0 1 1 1 0 GB virus C genotype envelope DUF1413 PF07205.9 124924.1_18522120_1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) Swm2 PF17083.3 124928.1_18522120_3 - 0.046 13.5 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Nucleolar protein Swm2 PT PF04886.10 133233.1_18522120_3 - 0.1 12.0 0.4 0.18 11.2 0.4 1.3 1 0 0 1 1 1 0 PT repeat KNOX1 PF03790.11 124942.1_18521120_3 - 0.073 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 KNOX1 domain Chorion_2 PF03964.13 048275.2_18522120_1 - 0.12 13.1 0.1 0.18 12.5 0.1 1.2 1 0 0 1 1 1 0 Chorion family 2 DUF2207 PF09972.7 133245.1_18526120_1 - 3 6.4 4.4 4.3 5.9 4.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NOA36 PF06524.10 124952.2_18523120_3 - 6.2 6.0 20.8 8 5.6 20.8 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.4 124952.2_18523120_3 - 7.7 6.1 7.6 14 5.2 7.6 1.3 1 0 0 1 1 1 0 FAM176 family Trypsin PF00089.24 133249.1_18524120_2 - 1.5e-56 191.6 0.1 2e-56 191.1 0.1 1.1 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.13 133249.1_18524120_2 - 0.0051 16.3 0.0 0.27 10.7 0.0 2.4 3 0 0 3 3 3 1 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.9 133249.1_18524120_2 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Stealth_CR1 PF17101.3 133250.1_18521120_3 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 DUF1516 PF07457.9 124966.1_18521120_3 - 0.059 13.5 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) CD52 PF15116.4 124972.1_18522120_3 - 0.23 11.4 2.8 0.2 11.6 0.6 1.9 2 0 0 2 2 2 0 CAMPATH-1 antigen PEHE PF15275.4 133261.1_18522120_2 - 0.023 15.2 0.7 0.032 14.7 0.7 1.3 1 0 0 1 1 1 0 PEHE domain HTH_41 PF14502.4 048294.1_18522120_1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Herpes_LMP2 PF07415.9 133267.1_18522120_1 - 0.0032 16.2 3.4 0.0035 16.0 3.4 1.2 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein DUF3619 PF12279.6 133267.1_18522120_1 - 0.099 12.8 1.1 0.16 12.2 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) Hyr1 PF15789.3 124982.1_18521120_2 - 0.11 11.9 0.7 0.18 11.3 0.7 1.3 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 PBP1_TM PF14812.4 133286.1_18521120_3 - 0.014 15.6 0.2 0.026 14.8 0.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4714 PF15833.3 133286.1_18521120_3 - 0.089 12.6 0.7 0.57 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4714) CENP-B_dimeris PF09026.8 133286.1_18521120_3 - 2.1 8.7 12.9 3 8.2 12.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Otopetrin PF03189.11 125034.1_18523120_2 - 0.035 12.8 6.5 0.046 12.4 6.5 1.1 1 0 0 1 1 1 0 Otopetrin Otopetrin PF03189.11 125035.1_18522120_1 - 0.011 14.4 6.5 0.014 14.1 6.5 1.0 1 0 0 1 1 1 0 Otopetrin SMN PF06003.10 125041.1_18521120_1 - 0.083 12.0 3.1 0.1 11.7 3.1 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) ADP_ribosyl_GH PF03747.12 125051.1_18521120_1 - 0.13 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF329 PF03884.12 003986.1_18525120_3 - 0.022 14.4 5.3 43 3.8 0.0 5.9 7 0 0 7 7 7 0 Domain of unknown function (DUF329) CK_II_beta PF01214.16 026600.1_18522120_1 - 3.2e-26 92.2 0.0 6.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026600.1_18522120_2 - 5.1e-07 29.6 0.3 6.8e-07 29.2 0.3 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026605.1_18523120_1 - 4.8e-07 29.7 1.0 6.7e-07 29.2 1.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026605.1_18523120_3 - 2.5e-26 92.5 0.1 3.8e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026612.1_18523120_2 - 4.8e-12 45.9 0.0 6.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 026627.1_18523120_3 - 6.6e-18 65.1 0.6 1.1e-17 64.3 0.6 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.16 001110696.2_18521001_1 - 1.8e-16 60.4 0.0 2.4e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Cuticle_2 PF08184.9 001110696.2_18521001_3 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Cuticle protein 7 isoform family Arm_3 PF16186.3 004027.1_18523120_1 - 0.53 9.7 4.9 1e+02 2.4 0.1 3.9 4 0 0 4 4 4 0 Atypical Arm repeat Root_cap PF06830.9 001112097.1_53723001_1 - 4e-28 97.2 0.4 9.2e-28 96.0 0.4 1.7 1 0 0 1 1 1 1 Root cap Conotoxin PF02950.15 001112097.1_53723001_1 - 0.017 15.9 2.9 0.038 14.9 2.9 1.6 1 0 0 1 1 1 0 Conotoxin FHIPEP PF00771.18 001111710.1_53723001_1 - 0.051 11.9 0.1 0.06 11.7 0.1 1.0 1 0 0 1 1 1 0 FHIPEP family Ureide_permease PF07168.9 001111710.1_53723001_1 - 0.087 11.4 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Ureide permease DUF788 PF05620.9 001111710.1_53723001_1 - 0.32 10.8 4.4 0.47 10.2 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) OAD_gamma PF04277.11 001111710.1_53723001_1 - 8.7 6.9 10.3 16 6.1 10.3 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AOX PF01786.15 001111710.1_53723001_3 - 6.6e-81 270.9 0.8 1e-80 270.3 0.8 1.2 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.11 001111710.1_53723001_3 - 0.00067 19.3 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 GST_N_3 PF13417.4 001111516.1_53722001_1 - 5.2e-18 65.1 0.0 1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001111516.1_53722001_1 - 4.1e-16 59.0 0.1 8.4e-16 58.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001111516.1_53722001_1 - 7.7e-11 42.0 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.2 001111516.1_53722001_1 - 0.0035 17.9 0.0 0.0058 17.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Spin-Ssty PF02513.15 001111516.1_53722001_2 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Spin/Ssty Family GST_C_2 PF13410.4 001111516.1_53722001_3 - 2.9e-07 30.2 0.0 4.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001111516.1_53722001_3 - 3.5e-07 30.2 0.0 5.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001111516.1_53722001_3 - 0.052 13.6 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cupin_1 PF00190.20 001111734.1_53723001_2 - 3.9e-46 156.2 0.0 2e-24 85.8 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.9 001111734.1_53723001_2 - 0.015 14.9 0.0 0.93 9.1 0.0 2.4 2 0 0 2 2 2 0 Cupin domain Cupin_3 PF05899.10 001111734.1_53723001_2 - 0.025 14.1 0.1 0.47 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) ARD PF03079.12 001111734.1_53723001_2 - 0.062 13.3 0.1 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 ARD/ARD' family CHASE PF03924.11 001112443.1_53727001_1 - 1.7e-39 135.6 0.2 5.2e-39 134.0 0.2 1.8 2 0 0 2 2 2 1 CHASE domain HATPase_c PF02518.24 001112443.1_53727001_1 - 5e-35 120.3 0.0 1.2e-34 119.0 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.22 001112443.1_53727001_1 - 1.1e-21 77.0 0.2 1.6e-19 70.0 0.0 3.0 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.23 001112443.1_53727001_1 - 1.8e-16 59.8 0.1 4.1e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.4 001112443.1_53727001_1 - 0.05 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WRC PF08879.8 001112571.1_53724001_2 - 6.2e-16 57.8 11.9 1e-15 57.0 11.9 1.4 1 0 0 1 1 1 1 WRC QLQ PF08880.9 001112571.1_53724001_2 - 8.1e-14 51.0 0.4 1.8e-13 49.8 0.4 1.7 1 0 0 1 1 1 1 QLQ Troponin-I_N PF11636.6 001112571.1_53724001_3 - 5.2 7.0 9.5 0.14 12.0 2.4 2.1 2 0 0 2 2 2 0 Troponin I residues 1-32 PBP PF01161.18 001112786.1_53722001_3 - 1.7e-14 54.1 0.0 2.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Lipase_GDSL PF00657.20 001137175.1_53723001_1 - 5.6e-10 39.4 0.0 7.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cu-oxidase_2 PF07731.12 001137204.1_53724001_2 - 2e-42 144.0 15.7 4.3e-37 126.8 1.1 4.3 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase_3 PF07732.13 001137204.1_53724001_2 - 3.4e-39 133.4 0.4 3.4e-39 133.4 0.4 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.20 001137204.1_53724001_2 - 3.9e-33 114.7 0.0 2.6e-32 112.0 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Nucleotid_trans PF03407.14 001137224.1_53724001_2 - 1.5e-55 188.3 0.0 2.1e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase IncA PF04156.12 001137224.1_53724001_2 - 0.1 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 IncA protein Fasciclin PF02469.20 001137495.1_53723001_2 - 3e-21 75.9 0.4 4.1e-21 75.4 0.4 1.2 1 0 0 1 1 1 1 Fasciclin domain Y_phosphatase2 PF03162.11 001137004.1_53723001_1 - 4.5e-61 205.1 0.0 6.2e-61 204.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.4 001137004.1_53723001_1 - 3.4e-07 30.3 0.0 5.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.18 001137004.1_53723001_1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001137004.1_53723001_1 - 0.0088 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thaumatin PF00314.15 001137513.1_53722001_2 - 1.1e-74 250.7 11.0 1.3e-74 250.5 11.0 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_tranf_2_3 PF13641.4 001137535.1_53725001_1 - 2.4e-23 83.1 0.5 3.5e-23 82.6 0.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.4 001137535.1_53725001_1 - 2.3e-22 79.7 1.6 2.3e-22 79.7 1.6 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.24 001137535.1_53725001_1 - 3e-16 59.6 0.0 5.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.4 001137535.1_53725001_1 - 3.2e-09 36.4 0.1 5.1e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 FlaG PF03646.13 001137535.1_53725001_1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 FlaG protein Chitin_synth_2 PF03142.13 001137535.1_53725001_1 - 0.17 10.3 4.6 0.62 8.5 0.0 2.2 1 1 1 2 2 2 0 Chitin synthase Gp_dh_C PF02800.18 001137324.1_53724001_2 - 3.6e-70 234.5 0.0 6.3e-70 233.7 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001137324.1_53724001_2 - 2.4e-37 127.2 0.1 6.4e-37 125.8 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001137324.1_53724001_2 - 0.0085 16.1 0.0 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.17 001137324.1_53724001_2 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ada_Zn_binding PF02805.14 001137324.1_53724001_2 - 0.12 12.3 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 Metal binding domain of Ada DUF563 PF04577.12 001136828.1_53724001_3 - 9.7e-21 74.7 0.0 1.5e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Serinc PF03348.13 001137340.1_53724001_3 - 2.4e-113 379.2 13.3 3.4e-113 378.7 13.3 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) adh_short PF00106.23 001137349.1_53723001_3 - 3.4e-51 173.4 0.0 4.5e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001137349.1_53723001_3 - 5e-38 130.8 0.1 7.1e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.8 001137349.1_53723001_3 - 6.9e-10 38.6 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.8 001137349.1_53723001_3 - 4e-09 36.5 0.9 9.1e-09 35.3 0.9 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.4 001137349.1_53723001_3 - 0.00099 18.9 0.2 0.0016 18.3 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding LEM PF03020.13 001137349.1_53723001_3 - 0.05 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 LEM domain RmlD_sub_bind PF04321.15 001137349.1_53723001_3 - 0.089 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.13 001137349.1_53723001_3 - 0.12 12.0 0.2 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Tub PF01167.16 001137378.1_53725001_1 - 8.6e-88 293.5 0.0 1.1e-87 293.2 0.0 1.1 1 0 0 1 1 1 1 Tub family F-box PF00646.31 001137378.1_53725001_1 - 9.9e-07 28.4 0.1 2.1e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001137378.1_53725001_1 - 2.9e-05 23.7 0.3 6.6e-05 22.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like DUF3527 PF12043.6 001137378.1_53725001_1 - 0.022 14.2 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) LRR_8 PF13855.4 001136635.1_53723001_1 - 2.1e-12 46.4 9.5 2.9e-07 30.0 0.1 3.3 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.5 001136635.1_53723001_1 - 1.7e-07 31.2 11.1 0.031 14.6 0.3 4.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.4 001136635.1_53723001_1 - 8e-06 25.4 0.2 3.4 7.8 0.0 4.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.31 001136635.1_53723001_1 - 0.00022 21.1 13.4 2.8 8.6 0.0 7.0 5 1 1 6 6 6 2 Leucine Rich Repeat LRRNT_2 PF08263.10 001136635.1_53723001_1 - 0.00039 20.5 0.0 0.00081 19.5 0.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LEA_2 PF03168.11 001137392.1_53724001_1 - 4.5e-15 55.8 0.0 7.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein F-box PF00646.31 001137392.1_53724001_1 - 0.073 12.8 3.8 0.21 11.4 3.8 1.7 1 0 0 1 1 1 0 F-box domain 2_5_RNA_ligase2 PF13563.4 001136649.1_53723001_2 - 0.14 11.9 0.0 0.49 10.2 0.1 1.8 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Pkinase PF00069.23 001137410.1_53724001_3 - 6.4e-71 238.7 0.0 8.3e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001137410.1_53724001_3 - 1.6e-33 116.0 0.0 2.6e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001137410.1_53724001_3 - 0.021 14.6 0.0 0.047 13.5 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001137410.1_53724001_3 - 0.044 13.2 0.1 0.074 12.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.12 001137410.1_53724001_3 - 0.096 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.15 001136916.1_53726001_2 - 2.1e-40 138.5 0.0 2.9e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001136916.1_53726001_2 - 1.1e-37 129.7 0.0 1.7e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.5 001136916.1_53726001_2 - 4.4e-13 49.0 15.6 2.9e-06 27.3 0.3 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001136916.1_53726001_2 - 2.1e-11 43.3 16.9 2.1e-05 24.1 7.5 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRRNT_2 PF08263.10 001136916.1_53726001_2 - 1.6e-10 40.9 1.4 3.4e-10 39.9 1.4 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.31 001136916.1_53726001_2 - 1.9e-06 27.4 16.1 0.0046 17.1 1.4 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.4 001136916.1_53726001_2 - 0.0006 19.5 7.6 0.73 9.9 0.2 4.4 4 0 0 4 4 4 2 Leucine Rich repeat Mid2 PF04478.10 001136916.1_53726001_2 - 0.025 14.3 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.4 001136916.1_53726001_2 - 0.076 13.7 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.13 001136916.1_53726001_2 - 0.59 9.8 3.2 1.4 8.6 3.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.8 001136916.1_53726001_2 - 1.6 8.1 6.4 3.8 6.9 6.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Flp1_like PF16982.3 001136916.1_53726001_2 - 6.5 6.1 7.2 14 5.0 7.2 1.5 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain CCD48 PF15799.3 001139123.1_53723001_2 - 0.021 13.1 0.1 0.025 12.9 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 WD40 PF00400.30 001137981.1_53723001_2 - 4.3e-35 119.0 13.1 1.4e-06 28.8 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001137981.1_53723001_2 - 2.5e-18 66.0 0.0 8.1e-07 29.1 0.0 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001137981.1_53723001_2 - 5.5e-06 26.3 0.0 0.019 14.7 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001137981.1_53723001_2 - 2.6e-05 23.2 1.1 0.068 12.0 0.0 3.5 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.6 001137981.1_53723001_2 - 0.019 13.5 0.0 1.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.3 001137981.1_53723001_2 - 0.14 11.3 0.0 0.88 8.7 0.0 2.1 3 0 0 3 3 3 0 WD40-like domain PQQ_3 PF13570.4 001137981.1_53723001_2 - 1.6 9.2 0.0 1.6 9.2 0.0 4.3 6 0 0 6 6 6 0 PQQ-like domain MRP-L20 PF12824.5 001138895.1_53723001_3 - 3e-08 33.9 1.3 3.1e-08 33.8 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Bot1p PF12298.6 001138895.1_53723001_3 - 3.4e-07 30.5 0.2 5.7e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein TFIIS_C PF01096.16 001138223.1_53722001_3 - 1.7e-16 59.6 8.7 1.7e-16 59.6 8.7 2.6 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.14 001138223.1_53722001_3 - 0.0028 17.4 0.7 0.0028 17.4 0.7 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.4 001138223.1_53722001_3 - 0.005 16.6 2.8 0.005 16.6 2.8 2.3 2 0 0 2 2 2 1 Nudix N-terminal Rad60-SLD_2 PF13881.4 001138684.1_53724001_1 - 1.6e-37 127.8 0.0 2.5e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.21 001138684.1_53724001_1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.7 001138684.1_53724001_1 - 0.027 14.9 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Torus PF16131.3 001137776.1_53726001_3 - 3.2e-08 34.1 0.2 8.7e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.22 001137776.1_53726001_3 - 3.1e-06 26.8 6.7 6.6e-06 25.8 6.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.20 001137776.1_53726001_3 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.16 001137776.1_53726001_3 - 0.13 12.3 0.1 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain ETC_C1_NDUFA4 PF04800.10 001138926.1_53722001_2 - 5.6e-32 109.7 0.2 9.7e-32 108.9 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region DAGK_cat PF00781.22 001139394.1_53723001_3 - 1.3e-27 95.8 0.0 1.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.19 001139394.1_53723001_3 - 0.00015 21.0 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase PFK PF00365.18 001138475.1_53725001_2 - 1.1e-31 110.2 0.2 3.4e-31 108.5 0.2 1.7 1 1 0 1 1 1 1 Phosphofructokinase RuvX PF03652.13 001138475.1_53725001_2 - 0.093 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Fasciclin PF02469.20 001138256.1_53724001_3 - 2.2e-19 69.8 0.0 7.1e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain RNase_T PF00929.22 001138030.1_53723001_3 - 2.9e-32 112.3 0.1 3.8e-32 112.0 0.1 1.1 1 0 0 1 1 1 1 Exonuclease URO-D PF01208.15 001138040.2_53723001_3 - 8.5e-98 327.5 0.0 1.1e-97 327.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) peroxidase PF00141.21 001137818.1_53723001_1 - 2.3e-69 233.5 0.0 3.2e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase RRM_1 PF00076.20 001138504.1_53722001_1 - 4.3e-19 68.0 0.0 6.3e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thaumatin PF00314.15 001138349.2_53723001_2 - 3.8e-77 258.8 7.9 4.7e-77 258.5 7.9 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.3 001138349.2_53723001_2 - 0.00012 21.3 0.0 0.0017 17.6 0.0 2.0 2 0 0 2 2 2 1 Beta-1,3-glucanase HAD_2 PF13419.4 001138584.1_53723001_3 - 1.1e-18 67.8 0.0 1.6e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.24 001138584.1_53723001_3 - 6.5e-13 49.3 0.2 2.9e-12 47.2 0.1 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.4 001138584.1_53723001_3 - 3e-09 36.7 0.1 6.4e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.5 001138584.1_53723001_3 - 0.014 15.7 0.0 0.033 14.4 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.16 001138584.1_53723001_3 - 0.14 11.8 0.0 0.54 9.9 0.0 1.8 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase F-box PF00646.31 001138817.1_53724001_3 - 4.7e-06 26.2 2.7 1.3e-05 24.8 2.7 1.8 1 0 0 1 1 1 1 F-box domain Mg296 PF09644.8 001138817.1_53724001_3 - 0.058 13.4 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Mg296 protein F-box-like PF12937.5 001138817.1_53724001_3 - 0.23 11.2 2.2 0.49 10.2 2.2 1.6 1 0 0 1 1 1 0 F-box-like AUX_IAA PF02309.14 001139294.1_53723001_1 - 1.5e-25 90.3 0.0 2.3e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 AUX/IAA family AUX_IAA PF02309.14 001139294.1_53723001_2 - 1.9e-30 106.4 0.1 2.7e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 AUX/IAA family Myb_DNA-binding PF00249.29 001137949.1_53723001_2 - 8.7e-07 28.9 0.0 2.6e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.29 001137949.1_53723001_3 - 2.7e-20 72.1 0.1 1.4e-14 53.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001137949.1_53723001_3 - 3.6e-12 46.2 0.1 2.2e-06 27.7 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001137949.1_53723001_3 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Ribosomal_S26e PF01283.17 001138411.1_53722001_3 - 3.8e-52 175.1 9.2 5e-52 174.7 9.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e FAM27 PF15832.3 001138411.1_53722001_3 - 0.048 14.1 0.7 0.048 14.1 0.7 2.0 2 0 0 2 2 2 0 FAM27 D and E protein family DUF4604 PF15377.4 001137951.1_53723001_1 - 0.05 13.9 14.2 0.071 13.4 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Isochorismatase PF00857.18 001137951.1_53723001_2 - 1.1e-23 84.2 0.0 1.4e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family IDO PF01231.16 001137951.1_53723001_3 - 0.42 9.2 3.5 0.57 8.8 3.5 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF4604 PF15377.4 001137951.1_53723001_3 - 0.76 10.1 18.8 1 9.7 18.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Mog1 PF04603.10 001138188.1_53723001_2 - 3.7e-36 124.4 0.0 4.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein APS_kinase PF01583.18 001143471.1_53723001_1 - 6.4e-70 234.0 0.0 9e-70 233.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.4 001143471.1_53723001_1 - 1.2e-05 25.4 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.25 001143471.1_53723001_1 - 0.0012 19.3 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.4 001143471.1_53723001_1 - 0.0021 18.3 0.0 0.0033 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.4 001143471.1_53723001_1 - 0.0029 17.1 0.2 0.006 16.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain CbiA PF01656.21 001143471.1_53723001_1 - 0.003 17.5 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.4 001143471.1_53723001_1 - 0.0034 17.8 0.0 0.005 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.4 001143471.1_53723001_1 - 0.0046 16.4 0.1 0.19 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.8 001143471.1_53723001_1 - 0.0077 15.6 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ArgK PF03308.14 001143471.1_53723001_1 - 0.008 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 ArgK protein NACHT PF05729.10 001143471.1_53723001_1 - 0.0095 15.7 0.2 0.019 14.7 0.2 1.5 1 0 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.15 001143471.1_53723001_1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.10 001143471.1_53723001_1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.4 001143471.1_53723001_1 - 0.041 14.0 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001143471.1_53723001_1 - 0.072 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.4 001143471.1_53723001_1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.7 001143471.1_53723001_1 - 0.14 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.20 001143471.1_53723001_1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ParA PF10609.7 001143471.1_53723001_1 - 0.23 10.7 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase CBFD_NFYB_HMF PF00808.21 001143478.1_53723001_1 - 9.6e-21 73.7 1.4 1.5e-20 73.1 1.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001143478.1_53723001_1 - 2.3e-16 60.3 2.9 3.6e-16 59.6 2.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 BAF1_ABF1 PF04684.11 001143478.1_53723001_1 - 0.063 12.1 3.1 0.1 11.4 3.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MS_channel PF00924.16 001143478.1_53723001_1 - 0.12 11.8 0.4 0.17 11.3 0.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel ABATE PF07336.9 001143265.1_53723001_2 - 0.057 14.0 6.1 0.12 12.9 6.1 1.5 1 0 0 1 1 1 0 Putative stress-induced transcription regulator DUF572 PF04502.11 001143265.1_53723001_2 - 0.096 12.1 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PPV_E1_N PF00524.16 001143265.1_53723001_2 - 0.15 12.4 1.7 0.25 11.6 1.7 1.3 1 0 0 1 1 1 0 E1 Protein, N terminal domain FAM176 PF14851.4 001143265.1_53723001_2 - 3.6 7.1 9.3 0.33 10.5 3.4 2.0 2 0 0 2 2 2 0 FAM176 family LEA_2 PF03168.11 001143112.1_53723001_1 - 5.7e-11 42.7 0.0 9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein Glyco_hydro_81 PF03639.11 001143119.1_53725001_3 - 8.2e-177 589.8 0.0 9.5e-177 589.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Abhydrolase_3 PF07859.11 001143135.1_53723001_3 - 3.8e-54 183.6 0.0 5.4e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.26 001143135.1_53723001_3 - 6.8e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.7 001143135.1_53723001_3 - 0.11 11.3 0.0 0.32 9.7 0.0 1.7 1 1 0 1 1 1 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.6 001143135.1_53723001_3 - 0.13 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RRM_1 PF00076.20 001143176.1_53722001_3 - 8.9e-19 67.0 0.0 1.7e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001143176.1_53722001_3 - 0.033 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif APG6 PF04111.10 001143176.1_53722001_3 - 0.061 12.6 1.5 0.07 12.4 1.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Nup35_RRM_2 PF14605.4 001143176.1_53722001_3 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Galactosyl_T PF01762.19 001143184.1_53723001_2 - 1.2e-11 44.7 0.0 3.7e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 Galactosyltransferase Lipase_GDSL PF00657.20 001143445.1_53723001_1 - 3.4e-19 69.5 0.0 4.4e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.4 001143445.1_53723001_1 - 0.0013 19.0 0.1 0.0032 17.8 0.1 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SANTA PF09133.8 001151949.1_53724001_2 - 2.4e-22 79.1 0.0 5.4e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 SANTA (SANT Associated) PALP PF00291.23 001153247.1_53724001_3 - 3.8e-66 223.3 0.2 4.8e-66 223.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MAP70 PF07058.9 001158083.1_53725001_2 - 1e-271 902.4 42.4 1.3e-271 902.1 42.4 1.0 1 0 0 1 1 1 1 Microtubule-associated protein 70 Lebercilin PF15619.4 001158083.1_53725001_2 - 0.00019 21.0 62.4 0.067 12.7 9.8 5.3 2 1 2 4 4 4 4 Ciliary protein causing Leber congenital amaurosis disease FAM76 PF16046.3 001158083.1_53725001_2 - 0.0025 17.1 3.0 0.0025 17.1 3.0 3.8 3 1 1 4 4 4 3 FAM76 protein zf-C4H2 PF10146.7 001158083.1_53725001_2 - 0.01 16.0 1.5 0.01 16.0 1.5 4.1 1 1 3 5 5 5 0 Zinc finger-containing protein DUF3165 PF11364.6 001147104.1_53723001_2 - 0.051 13.8 0.8 0.074 13.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) DUF761 PF05553.9 001147104.1_53723001_3 - 8.5e-10 37.9 4.5 1.3e-09 37.3 4.5 1.3 1 0 0 1 1 1 1 Cotton fibre expressed protein SWIRM PF04433.15 001147851.1_53724001_2 - 3.4e-23 81.7 0.0 7.7e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.3 001147851.1_53724001_2 - 1.4e-12 47.4 9.3 2.7e-12 46.4 9.3 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.29 001147851.1_53724001_2 - 1.7e-10 40.8 0.1 2.7e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001147851.1_53724001_2 - 8e-08 32.3 0.1 1.5e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fzo_mitofusin PF04799.11 001147851.1_53724001_2 - 2.2 7.6 6.8 3 7.2 4.4 2.1 1 1 1 2 2 2 0 fzo-like conserved region Cu_bind_like PF02298.15 001158848.1_53722001_3 - 1.6e-19 69.6 0.8 2.7e-19 68.9 0.8 1.3 1 0 0 1 1 1 1 Plastocyanin-like domain Methyltransf_31 PF13847.4 001158848.1_53722001_3 - 0.017 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Porin_5 PF16930.3 001158848.1_53722001_3 - 0.11 10.9 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Putative porin RCDG1 PF15725.3 001158848.1_53722001_3 - 1.3 9.4 6.7 3 8.2 6.7 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein EF-hand_1 PF00036.30 001158341.1_53722001_3 - 9.5e-35 115.4 12.5 1.3e-08 33.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001158341.1_53722001_3 - 3.9e-31 105.0 11.0 4.9e-08 32.0 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001158341.1_53722001_3 - 1.1e-30 105.8 5.7 6e-15 55.3 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001158341.1_53722001_3 - 1.1e-30 102.7 9.9 3e-09 35.9 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.4 001158341.1_53722001_3 - 2e-23 81.8 19.6 2.7e-13 49.4 0.5 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.5 001158341.1_53722001_3 - 2.6e-09 36.9 0.3 0.00061 19.6 0.1 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001158341.1_53722001_3 - 5.8e-07 29.6 0.1 0.0087 16.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.7 001158341.1_53722001_3 - 6.4e-07 29.5 0.1 0.0079 16.4 0.0 2.4 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.11 001158341.1_53722001_3 - 0.00046 20.0 0.1 0.29 10.9 0.0 2.9 2 1 1 3 3 3 2 Caleosin related protein p25-alpha PF05517.10 001158341.1_53722001_3 - 0.0036 17.3 0.2 0.45 10.5 0.1 2.4 1 1 2 3 3 3 1 p25-alpha SurA_N_3 PF13624.4 001158341.1_53722001_3 - 0.045 13.4 0.1 0.35 10.5 0.1 2.0 1 1 1 2 2 2 0 SurA N-terminal domain VCBS PF13517.4 001158341.1_53722001_3 - 0.095 13.2 7.0 0.95 10.0 0.3 2.7 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella GATA-N PF05349.10 001149354.1_53722001_2 - 0.001 19.3 0.1 0.0016 18.6 0.1 1.4 1 0 0 1 1 1 1 GATA-type transcription activator, N-terminal RNA_GG_bind PF10258.7 001149354.1_53722001_2 - 0.062 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 PHAX RNA-binding domain BSD PF03909.15 001155800.1_53724001_2 - 3.2e-10 39.7 0.0 6.3e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 BSD domain HMG-CoA_red PF00368.16 001148564.1_53723001_1 - 5.7e-106 354.5 3.7 6.7e-106 354.3 3.7 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase F-box PF00646.31 001155547.1_53724001_2 - 7.4e-06 25.6 1.3 7.4e-06 25.6 1.3 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.5 001155547.1_53724001_2 - 2.9e-05 23.7 0.4 6e-05 22.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.5 001155547.1_53724001_2 - 0.015 15.6 4.4 4.7 7.6 0.0 4.1 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) FBD PF08387.8 001155547.1_53724001_2 - 0.17 11.6 3.1 0.39 10.5 0.0 2.9 3 0 0 3 3 3 0 FBD CBFD_NFYB_HMF PF00808.21 001147861.1_53723001_2 - 5.8e-28 96.8 0.3 8.7e-28 96.3 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001147861.1_53723001_2 - 0.0033 17.7 0.1 0.0055 17.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001147861.1_53723001_2 - 0.0074 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.11 001147861.1_53723001_2 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Prenyltransf PF01255.17 001158352.1_53723001_3 - 9.4e-64 214.8 0.0 1.1e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Response_reg PF00072.22 001146886.1_53723001_2 - 5.9e-19 68.2 0.0 3.9e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain PRIMA1 PF16101.3 001153521.1_53722001_1 - 0.0011 18.8 8.1 0.0011 18.8 8.1 1.9 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 PSK PF06404.10 001153521.1_53722001_2 - 9.9e-20 71.2 2.3 3.1e-19 69.6 1.4 2.2 2 1 0 2 2 2 1 Phytosulfokine precursor protein (PSK) DUF1180 PF06679.10 001153521.1_53722001_2 - 0.0098 16.2 0.5 0.016 15.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) UPF0139 PF03669.11 001159452.1_53722001_2 - 1.5e-35 120.8 0.0 2.4e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) PP2 PF14299.4 001155813.1_53722001_1 - 5.2e-37 126.9 0.0 7.1e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Phloem protein 2 MRP PF09387.8 001155813.1_53722001_1 - 0.062 13.1 0.2 0.097 12.5 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP TCP PF03634.11 001146893.1_53724001_3 - 8.4e-32 110.7 2.1 5.4e-31 108.1 0.1 2.6 2 1 0 2 2 2 1 TCP family transcription factor Pex14_N PF04695.11 001146893.1_53724001_3 - 9.9 6.7 10.3 23 5.5 10.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region XS PF03468.12 001150482.1_53724001_3 - 3.5e-19 69.0 0.0 1e-18 67.5 0.0 1.8 2 0 0 2 2 2 1 XS domain IQ PF00612.25 001156327.1_53724001_1 - 0.0016 17.9 2.9 0.0019 17.7 1.1 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif CAAD PF14159.4 001147882.1_53722001_1 - 1.5e-31 108.0 0.1 2e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF615 PF04751.12 001155571.1_53723001_3 - 4.3e-42 143.6 2.5 5.8e-42 143.1 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF615) Patatin PF01734.20 001148835.1_53724001_1 - 0.00014 22.0 7.5 0.00014 22.0 7.5 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase ANTH PF07651.14 001157869.1_53724001_3 - 1.8e-39 135.2 0.0 3.4e-32 111.4 0.0 2.5 2 1 0 2 2 2 2 ANTH domain Rieske PF00355.24 001157871.1_53725001_2 - 3.5e-22 78.0 0.3 3.5e-22 78.0 0.3 1.7 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain PaO PF08417.10 001157871.1_53725001_2 - 3.2e-15 55.9 0.1 6.2e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase YscO PF07321.10 001157871.1_53725001_2 - 0.03 14.2 0.2 0.047 13.5 0.2 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO HrpB7 PF09486.8 001157871.1_53725001_2 - 0.037 14.3 0.3 0.064 13.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Rab_eff_C PF04698.10 001157871.1_53725001_2 - 0.21 9.7 0.1 0.29 9.3 0.1 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus TAT_signal PF10518.7 001157871.1_53725001_2 - 2.3 8.1 7.4 3.9 7.4 7.4 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Pkinase PF00069.23 001148124.2_53724001_2 - 1.6e-44 152.1 0.0 2.1e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001148124.2_53724001_2 - 1.3e-42 145.8 0.0 2.3e-42 144.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Aldo_ket_red PF00248.19 001148596.1_53724001_1 - 8.2e-70 235.1 0.0 1.1e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family potato_inhibit PF00280.16 001245885.1_53721001_1 - 1.4e-25 89.6 1.8 2e-25 89.1 1.8 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.6 001245885.1_53721001_1 - 0.049 13.5 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I78 family NHL PF01436.19 001245885.1_53721001_1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 NHL repeat DNA_RNApol_7kD PF03604.11 001157366.1_53722001_1 - 1.4e-14 53.3 4.7 2.5e-14 52.5 4.7 1.5 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_10 PF10058.7 001157366.1_53722001_1 - 0.07 12.7 0.5 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_6 PF14599.4 001157366.1_53722001_1 - 0.086 12.7 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon HypA PF01155.17 001157366.1_53722001_1 - 0.092 12.6 0.5 0.15 11.9 0.5 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.4 001157366.1_53722001_1 - 3.2 7.5 6.0 4.2 7.1 2.8 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.23 001147404.1_53724001_1 - 1.5e-39 135.9 0.0 2.2e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001147404.1_53724001_1 - 8.6e-37 126.7 0.0 1.8e-36 125.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase LysM PF01476.18 001147404.1_53724001_1 - 1.5e-08 34.4 0.0 0.0045 16.9 0.0 3.2 3 0 0 3 3 3 2 LysM domain Phage_portal_2 PF05136.11 001147404.1_53724001_1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family Cyclin_N PF00134.21 001158642.1_53724001_3 - 2.7e-16 59.4 0.0 4.3e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cpn10 PF00166.19 001159463.1_53721001_3 - 7.2e-25 86.8 0.0 8.8e-25 86.5 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit UDPG_MGDP_dh_N PF03721.12 001158389.1_53724001_3 - 2.2e-63 213.1 0.0 3.7e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.13 001158389.1_53724001_3 - 2.8e-35 120.8 0.0 7.1e-35 119.5 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.17 001158389.1_53724001_3 - 4.4e-31 106.8 0.0 7.5e-31 106.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain COX6B PF02297.15 001146917.1_53722001_1 - 3.8e-17 62.2 3.8 7.9e-17 61.1 3.8 1.6 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.3 001146917.1_53722001_1 - 0.05 13.5 0.5 0.11 12.4 0.5 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF1631 PF07793.9 001146917.1_53722001_1 - 0.89 7.8 7.9 1.8 6.7 7.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) DUF1510 PF07423.9 001146917.1_53722001_1 - 2 7.7 13.3 2.7 7.3 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.4 001146917.1_53722001_1 - 3.1 7.6 14.3 4.2 7.1 14.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF913 PF06025.10 001146917.1_53722001_1 - 4.1 6.1 5.7 5.2 5.8 5.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.10 001146917.1_53722001_1 - 6.6 6.3 11.1 8.6 6.0 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.15 001146917.1_53722001_1 - 7.1 5.1 8.5 9.1 4.8 8.5 1.1 1 0 0 1 1 1 0 Presenilin Methyltr_RsmB-F PF01189.15 001152373.1_53725001_2 - 3e-36 124.8 0.0 5.1e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.18 001152373.1_53725001_2 - 2.5e-06 27.2 1.6 4.4e-05 23.2 1.6 2.5 1 1 0 1 1 1 1 PUA domain Methyltransf_31 PF13847.4 001152373.1_53725001_2 - 0.00032 20.4 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain FtsJ PF01728.17 001152373.1_53725001_2 - 0.0044 17.0 0.0 0.023 14.7 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase UL11 PF11094.6 001152373.1_53725001_2 - 0.25 11.1 1.1 1.5 8.7 0.0 2.6 3 0 0 3 3 3 0 Membrane-associated tegument protein TAXi_N PF14543.4 001156865.1_53724001_2 - 1.3e-41 142.7 10.1 2e-41 142.1 10.1 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.21 001156865.1_53724001_2 - 4e-31 108.5 5.7 6.5e-30 104.5 5.7 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.4 001156865.1_53724001_2 - 1.4e-27 96.3 0.0 2.3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Nup_retrotrp_bd PF10599.7 001156865.1_53724001_2 - 1.9 9.0 5.3 11 6.6 0.3 2.9 2 0 0 2 2 2 0 Retro-transposon transporting motif UFD1 PF03152.12 001155088.1_53723001_1 - 9.9e-80 265.9 0.0 1.3e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 MSC PF09402.8 001150113.1_53723001_3 - 1.2e-13 51.2 17.2 3.7e-11 43.0 17.3 2.2 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain SecE PF00584.18 001150113.1_53723001_3 - 0.21 11.4 1.2 0.5 10.2 0.4 1.9 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Auxin_inducible PF02519.12 001159160.1_53722001_2 - 1.7e-17 63.3 0.0 2.6e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Auxin responsive protein Macoilin PF09726.7 001151822.1_53722001_3 - 0.46 8.9 2.1 0.53 8.6 2.1 1.1 1 0 0 1 1 1 0 Transmembrane protein UPF0544 PF15749.3 001150728.1_53723001_1 - 3.3e-17 63.0 3.2 6.2e-17 62.2 0.4 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0544 Herpes_BLLF1 PF05109.11 001150728.1_53723001_1 - 0.025 12.5 1.6 0.042 11.7 1.6 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) zf-Sec23_Sec24 PF04810.13 001150728.1_53723001_1 - 1.7 8.6 4.8 0.77 9.7 2.0 1.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger ATP-synt_S1 PF05827.10 001150516.1_53723001_3 - 0.00057 19.6 0.0 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) NinF PF05810.10 001150516.1_53723001_3 - 0.34 10.7 1.6 0.93 9.3 1.6 1.7 1 0 0 1 1 1 0 NinF protein Snf7 PF03357.19 001148619.1_53724001_1 - 9.8e-13 47.9 1.7 1.8e-12 47.0 1.7 1.4 1 0 0 1 1 1 1 Snf7 DpaA_N PF16924.3 001148619.1_53724001_1 - 0.054 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain KIP1 PF07765.10 001152838.1_53723001_1 - 7.2e-34 115.6 0.9 7.2e-34 115.6 0.9 1.9 2 0 0 2 2 2 1 KIP1-like protein Shugoshin_N PF07558.9 001152838.1_53723001_1 - 0.053 13.3 1.6 9.2 6.1 0.2 3.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Mce4_CUP1 PF11887.6 001152838.1_53723001_1 - 0.053 12.8 0.3 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative TSC22 PF01166.16 001152838.1_53723001_1 - 0.15 12.3 2.3 0.77 10.0 0.1 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4407 PF14362.4 001152838.1_53723001_1 - 0.19 10.9 6.0 0.37 10.0 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-K PF11802.6 001152838.1_53723001_1 - 0.34 10.3 5.8 0.31 10.4 3.5 1.8 2 0 0 2 2 2 0 Centromere-associated protein K Phage_Mu_Gam PF07352.10 001152838.1_53723001_1 - 1 9.1 9.8 2 8.2 7.9 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF3292 PF11696.6 001152838.1_53723001_1 - 1.7 6.8 5.0 2.3 6.3 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) IncA PF04156.12 001152838.1_53723001_1 - 1.7 8.3 11.0 1.5 8.5 7.0 2.1 2 0 0 2 2 2 0 IncA protein DUF1515 PF07439.9 001152838.1_53723001_1 - 6.4 6.7 6.4 5 7.0 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF2058 PF09831.7 001152838.1_53723001_1 - 7.1 6.6 12.7 12 5.9 12.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Mnd1 PF03962.13 001152838.1_53723001_1 - 9.6 5.9 12.0 14 5.4 11.0 1.6 2 0 0 2 2 2 0 Mnd1 family ubiquitin PF00240.21 001156881.1_53724001_1 - 1.9e-19 69.0 0.0 3.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.29 001156881.1_53724001_1 - 5.3e-09 35.7 0.5 5.3e-09 35.7 0.5 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.6 001156881.1_53724001_1 - 5.1e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.4 001156881.1_53724001_1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001156881.1_53724001_1 - 0.08 13.4 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF771 PF05595.9 001156881.1_53724001_1 - 0.19 11.6 0.4 3.3 7.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF771) Peptidase_S8 PF00082.20 001148624.1_53724001_3 - 1.2e-28 100.1 0.6 2e-28 99.4 0.6 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.20 001148624.1_53724001_3 - 1.3e-08 34.7 0.0 3.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 PA domain ALG11_N PF15924.3 001148873.1_53724001_2 - 2.6e-85 285.6 0.1 3.6e-85 285.1 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.18 001148873.1_53724001_2 - 1.2e-25 89.9 0.0 1.9e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001148873.1_53724001_2 - 1.4e-11 44.8 0.0 2.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001148873.1_53724001_2 - 0.00014 22.0 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001148873.1_53724001_2 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 SpoU_methylase PF00588.17 001148159.2_53724001_3 - 1.7e-28 99.4 0.1 6.4e-25 87.8 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.10 001148159.2_53724001_3 - 7.7e-13 48.4 0.1 2e-12 47.0 0.1 1.7 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding PPR PF01535.18 001148163.2_53724001_1 - 4.8e-57 186.2 0.5 5.2e-10 38.8 0.1 9.9 10 0 0 10 10 10 9 PPR repeat PPR_1 PF12854.5 001148163.2_53724001_1 - 1.3e-53 178.3 0.4 3.3e-11 42.6 0.0 9.7 10 0 0 10 10 10 8 PPR repeat PPR_2 PF13041.4 001148163.2_53724001_1 - 2.4e-51 171.6 0.0 1.1e-08 35.1 0.0 9.4 7 1 2 9 9 9 9 PPR repeat family PPR_3 PF13812.4 001148163.2_53724001_1 - 7.4e-12 45.0 0.0 0.086 12.8 0.0 6.4 5 3 3 8 8 8 3 Pentatricopeptide repeat domain TPR_19 PF14559.4 001148163.2_53724001_1 - 8.7e-06 26.0 0.0 0.02 15.3 0.0 4.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.4 001148163.2_53724001_1 - 6.9e-05 22.5 0.0 3.5 7.7 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.4 001148163.2_53724001_1 - 7.3e-05 22.8 2.3 0.14 12.4 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.4 001148163.2_53724001_1 - 0.0026 18.3 14.6 3 8.8 0.1 7.3 5 2 4 9 9 7 2 Tetratricopeptide repeat TPR_2 PF07719.15 001148163.2_53724001_1 - 0.015 15.2 0.2 6.4 7.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.4 001148163.2_53724001_1 - 0.027 15.0 9.6 0.16 12.6 2.1 5.4 6 1 1 7 7 7 0 Tetratricopeptide repeat HisKA_3 PF07730.11 001148163.2_53724001_1 - 0.079 13.4 0.5 8.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Histidine kinase PNRC PF15365.4 001149610.1_53725001_3 - 5.9e-14 52.2 0.1 5.9e-14 52.2 0.1 2.3 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator Pollen_Ole_e_I PF01190.15 001147456.1_53723001_3 - 1.7e-19 69.8 0.8 2.5e-19 69.3 0.8 1.2 1 0 0 1 1 1 1 Pollen proteins Ole e I like PALP PF00291.23 001147205.1_53725001_1 - 6.4e-48 163.5 0.0 8.1e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BLOC1_2 PF10046.7 001154886.1_53722001_1 - 2.6e-28 98.0 1.1 3.5e-28 97.6 1.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAUS5 PF14817.4 001154886.1_53722001_1 - 0.00014 20.6 0.1 0.00016 20.3 0.1 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF489 PF04356.10 001154886.1_53722001_1 - 0.032 14.1 0.3 0.046 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) GCN5L1 PF06320.11 001154886.1_53722001_1 - 0.065 13.2 0.4 0.2 11.6 0.4 1.9 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) SlyX PF04102.10 001154886.1_53722001_1 - 0.17 12.4 0.6 1.4 9.5 0.1 2.3 2 1 0 2 2 2 0 SlyX NPV_P10 PF05531.10 001154886.1_53722001_1 - 1.2 9.6 3.4 6.7 7.1 1.3 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TPR_9 PF13371.4 001150768.1_53724001_3 - 0.0028 17.7 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat RPN7 PF10602.7 001150768.1_53724001_3 - 0.0083 15.7 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 DUF2358 PF10184.7 001150151.1_53723001_1 - 1.7e-38 131.2 0.0 3.2e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.5 001150151.1_53723001_1 - 8.6e-05 23.0 0.1 0.00017 22.1 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain DnaJ PF00226.29 001158199.1_53722001_1 - 8.5e-20 70.5 0.0 1.4e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-RING_2 PF13639.4 001154133.1_53723001_3 - 2.2e-14 53.3 4.4 2.2e-14 53.3 4.4 2.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.3 001154133.1_53723001_3 - 2.1e-11 43.2 1.2 2.1e-11 43.2 1.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001154133.1_53723001_3 - 1.7e-09 37.2 3.0 1.7e-09 37.2 3.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001154133.1_53723001_3 - 1.3e-08 34.8 7.5 1.3e-08 34.8 7.5 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001154133.1_53723001_3 - 2.1e-07 30.6 1.9 7e-07 28.9 1.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001154133.1_53723001_3 - 5.1e-06 26.2 2.9 5.1e-06 26.2 2.9 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 001154133.1_53723001_3 - 4.6e-05 23.3 1.1 0.0001 22.1 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.4 001154133.1_53723001_3 - 0.00022 20.9 3.2 0.00056 19.6 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.6 001154133.1_53723001_3 - 0.00024 21.1 0.8 0.00024 21.1 0.8 1.9 2 0 0 2 2 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.4 001154133.1_53723001_3 - 0.00046 20.0 0.9 0.0014 18.5 0.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.4 001154133.1_53723001_3 - 0.042 13.6 3.0 0.1 12.3 3.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IncA PF04156.12 001154133.1_53723001_3 - 0.096 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 IncA protein OAD_gamma PF04277.11 001154133.1_53723001_3 - 0.14 12.6 6.7 9.2 6.8 0.0 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Prok-RING_1 PF14446.4 001154133.1_53723001_3 - 0.71 9.7 5.7 0.54 10.1 0.3 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 RINGv PF12906.5 001154133.1_53723001_3 - 0.8 9.7 5.2 0.57 10.2 2.5 2.3 2 1 0 2 2 2 0 RING-variant domain zf-RING_4 PF14570.4 001154133.1_53723001_3 - 2.6 7.7 7.7 0.41 10.3 3.8 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Fer2 PF00111.25 001154133.1_53723001_3 - 4.5 7.2 9.0 18 5.3 3.7 2.5 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-RING-like PF08746.9 001154133.1_53723001_3 - 4.9 7.4 11.7 0.11 12.7 4.4 2.1 2 0 0 2 2 1 0 RING-like domain VIR_N PF15912.3 001152034.1_53723001_1 - 0.41 10.2 1.9 3.4 7.2 0.8 2.0 2 0 0 2 2 2 0 Virilizer, N-terminal DUF4636 PF15468.4 001152034.1_53723001_2 - 1.4 8.4 9.0 3 7.4 9.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) PC-Esterase PF13839.4 001151340.1_53724001_1 - 7.3e-79 265.3 0.0 9.2e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.4 001151340.1_53724001_1 - 5.7e-15 55.2 9.6 1.3e-14 54.1 9.6 1.6 1 0 0 1 1 1 1 PMR5 N terminal Domain Inhibitor_I9 PF05922.14 001156171.1_53722001_2 - 5e-10 39.8 0.0 7.8e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 PPR_1 PF12854.5 001153374.1_53723001_3 - 1.1e-43 146.4 1.6 5.5e-09 35.5 0.1 7.3 7 0 0 7 7 7 6 PPR repeat PPR_2 PF13041.4 001153374.1_53723001_3 - 4.1e-43 145.2 0.0 4.3e-15 55.5 0.1 6.0 1 1 5 6 6 6 6 PPR repeat family PPR PF01535.18 001153374.1_53723001_3 - 4.6e-39 129.8 2.0 1.5e-05 24.7 0.0 7.5 7 0 0 7 7 7 7 PPR repeat PPR_3 PF13812.4 001153374.1_53723001_3 - 1e-19 70.2 0.0 8.9e-08 32.0 0.0 4.3 3 1 1 4 4 4 4 Pentatricopeptide repeat domain PPR_long PF17177.2 001153374.1_53723001_3 - 7.2e-09 35.2 0.0 0.0006 19.1 0.0 2.7 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PROPR DEP PF00610.19 001153374.1_53723001_3 - 0.09 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PsbQ PF05757.9 001149432.1_53722001_3 - 0.028 14.0 1.9 0.039 13.6 1.9 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) RskA PF10099.7 001149432.1_53722001_3 - 0.048 13.8 4.6 0.062 13.5 4.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Pkinase PF00069.23 001152896.1_53725001_3 - 6.8e-26 91.1 0.0 1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001152896.1_53725001_3 - 3.3e-14 52.7 0.0 4.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001152896.1_53725001_3 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.12 001152896.1_53725001_3 - 0.011 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Reticulon PF02453.15 001155920.1_53723001_2 - 1.9e-46 157.7 3.9 2.4e-46 157.4 3.9 1.1 1 0 0 1 1 1 1 Reticulon Phi-29_GP16_7 PF06720.9 001151156.1_53723001_3 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 PB1 PF00564.22 001152447.1_53726001_3 - 9.2e-15 54.2 0.0 1.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 PB1 domain RhlB PF12300.6 001149276.1_53722001_1 - 0.039 14.0 4.4 0.082 13.0 4.5 1.5 1 1 0 1 1 1 0 ATP-dependent RNA helicase RhlB Bystin PF05291.9 001148689.1_53724001_3 - 8.3e-127 422.3 0.3 1.2e-126 421.8 0.3 1.2 1 0 0 1 1 1 1 Bystin ZF-HD_dimer PF04770.10 001152215.1_53723001_2 - 6.2e-26 90.4 7.3 1.2e-25 89.5 7.3 1.5 1 0 0 1 1 1 1 ZF-HD protein dimerisation region Homeobox PF00046.27 001152215.1_53723001_2 - 0.001 18.7 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain CAF1A PF12253.6 001152215.1_53723001_2 - 0.2 11.7 12.5 0.35 10.9 12.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Pox_Ag35 PF03286.12 001152215.1_53723001_2 - 0.23 11.1 13.1 0.44 10.2 13.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.9 001152215.1_53723001_2 - 0.25 11.2 7.7 0.44 10.4 7.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal RR_TM4-6 PF06459.10 001152215.1_53723001_2 - 0.32 10.6 11.2 0.49 10.0 11.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.12 001152215.1_53723001_2 - 0.34 9.0 7.0 0.48 8.5 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.10 001152215.1_53723001_2 - 0.49 8.4 12.2 0.71 7.9 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.8 001152215.1_53723001_2 - 0.61 10.4 13.2 1.4 9.2 13.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.6 001152215.1_53723001_2 - 0.75 9.8 18.9 1.8 8.6 18.9 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.10 001152215.1_53723001_2 - 1.3 8.2 12.8 2.5 7.3 12.8 1.4 1 0 0 1 1 1 0 NOA36 protein SWIRM-assoc_2 PF16496.3 001152215.1_53723001_2 - 1.4 7.6 9.7 2.3 6.9 9.7 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4746 PF15928.3 001152215.1_53723001_2 - 2 7.6 16.4 3.4 6.9 16.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.11 001152215.1_53723001_2 - 2.1 7.1 17.4 3.3 6.5 17.4 1.2 1 0 0 1 1 1 0 Paf1 Radial_spoke PF04712.10 001152215.1_53723001_2 - 2.3 6.9 11.2 3.6 6.3 11.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein TLP-20 PF06088.9 001152215.1_53723001_2 - 2.3 7.9 7.2 4 7.2 7.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF1510 PF07423.9 001152215.1_53723001_2 - 2.5 7.3 17.1 4.2 6.6 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DNA_pol_phi PF04931.11 001152215.1_53723001_2 - 4 5.3 16.8 5.4 4.9 16.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi eIF3_subunit PF08597.8 001152215.1_53723001_2 - 4.9 6.9 20.9 10 5.8 20.9 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Tim54 PF11711.6 001152215.1_53723001_2 - 5.1 5.6 10.2 9.1 4.8 10.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1770 PF08589.8 001152215.1_53723001_2 - 6 7.8 9.5 14 6.6 8.5 2.2 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Afi1 PF07792.10 001152215.1_53723001_2 - 6.5 7.1 10.1 15 5.9 10.1 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PPP4R2 PF09184.9 001152215.1_53723001_2 - 7.7 5.9 16.5 12 5.3 16.5 1.2 1 0 0 1 1 1 0 PPP4R2 TFB6 PF17110.3 001152215.1_53723001_2 - 8.8 5.9 6.4 14 5.2 6.4 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH F-actin_cap_A PF01267.15 001147982.2_53724001_1 - 5e-38 130.9 0.0 1.2e-35 123.1 0.0 2.1 2 0 0 2 2 2 2 F-actin capping protein alpha subunit F-actin_cap_A PF01267.15 001147982.2_53724001_2 - 8.8e-26 90.8 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Polysacc_synt_4 PF04669.11 001153908.1_53723001_1 - 7.4e-65 217.9 0.0 9.5e-65 217.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis Rho_N PF07498.10 001158236.1_53722001_3 - 2.6e-05 23.9 0.1 5.3e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain CNDH2_C PF16858.3 001151364.1_53725001_2 - 1e-41 143.6 1.8 6.9e-41 140.9 0.1 2.7 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_M PF16869.3 001151364.1_53725001_2 - 6.2e-38 130.6 2.9 1.7e-37 129.2 2.9 1.8 1 0 0 1 1 1 1 PF16858 CNDH2_N PF06278.9 001151364.1_53725001_2 - 3e-36 123.9 0.2 6.4e-36 122.8 0.2 1.6 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Rad21_Rec8_N PF04825.11 001151364.1_53725001_2 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein FAP PF07174.9 001148700.1_53723001_1 - 2.5 7.3 34.1 4.4 6.5 34.1 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) zf-RING_2 PF13639.4 001148700.1_53723001_3 - 1.3e-13 50.8 7.7 2.3e-13 50.0 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 001148700.1_53723001_3 - 3.9e-11 42.9 5.0 7.9e-11 41.9 5.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001148700.1_53723001_3 - 4.2e-09 35.8 4.3 8.4e-09 34.9 4.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001148700.1_53723001_3 - 1.2e-08 34.5 6.9 2e-08 33.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001148700.1_53723001_3 - 4.4e-07 29.7 1.1 8.9e-07 28.7 0.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001148700.1_53723001_3 - 7.4e-07 28.8 5.9 1.3e-06 28.0 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001148700.1_53723001_3 - 9.9e-06 25.2 4.1 1.7e-05 24.4 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001148700.1_53723001_3 - 2.6e-05 23.9 4.9 4.6e-05 23.2 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 001148700.1_53723001_3 - 4.9e-05 23.2 1.4 0.0001 22.1 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.4 001148700.1_53723001_3 - 0.0057 16.2 3.6 0.0057 16.2 3.6 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.3 001148700.1_53723001_3 - 0.013 15.0 4.9 0.022 14.3 4.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.4 001148700.1_53723001_3 - 0.021 14.5 5.5 0.04 13.6 5.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.4 001148700.1_53723001_3 - 0.047 13.5 4.0 0.18 11.6 1.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.6 001148700.1_53723001_3 - 0.11 12.6 2.9 0.23 11.5 2.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Baculo_IE-1 PF05290.9 001148700.1_53723001_3 - 0.17 11.7 0.9 0.25 11.2 0.9 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.4 001148700.1_53723001_3 - 0.41 10.7 5.6 1.6 8.8 5.6 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.27 001148700.1_53723001_3 - 1.5 8.6 5.7 3.1 7.6 5.7 1.6 1 0 0 1 1 1 0 PHD-finger Porin_3 PF01459.20 001155187.1_53723001_1 - 1.2e-80 270.7 0.1 1.4e-80 270.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin MDM10 PF12519.6 001155187.1_53723001_1 - 0.00029 19.7 0.7 0.00052 18.9 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 peroxidase PF00141.21 001147510.1_53723001_1 - 5.3e-77 258.4 0.7 7e-77 258.0 0.7 1.2 1 0 0 1 1 1 1 Peroxidase Hyccin PF09790.7 001147511.1_53724001_2 - 2.6e-70 236.9 0.0 3.3e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Hyccin PC4 PF02229.14 001158500.1_53722001_2 - 2.9e-22 77.9 0.0 5.4e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Exo_endo_phos PF03372.21 001152683.1_53723001_1 - 1.8e-07 31.2 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HMA PF00403.24 001154183.1_53723001_1 - 0.12 12.7 2.4 0.23 11.8 2.4 1.5 1 0 0 1 1 1 0 Heavy-metal-associated domain EF-hand_1 PF00036.30 001155706.1_53723001_2 - 3.4e-18 63.6 7.4 5e-06 25.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001155706.1_53723001_2 - 6.1e-14 50.7 8.1 2.3e-07 29.9 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.4 001155706.1_53723001_2 - 5.6e-13 49.0 7.5 1.7e-07 31.4 1.0 3.4 1 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.4 001155706.1_53723001_2 - 7.4e-13 47.2 5.8 0.0053 16.5 0.4 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.4 001155706.1_53723001_2 - 9.3e-08 31.6 5.0 0.00019 21.0 0.7 2.9 2 2 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001155706.1_53723001_2 - 0.0035 17.5 1.1 0.016 15.4 0.6 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001155706.1_53723001_2 - 0.011 15.5 0.4 0.56 10.1 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand LcrV PF04792.10 001155706.1_53723001_2 - 0.055 12.6 0.1 0.097 11.8 0.1 1.3 1 0 0 1 1 1 0 V antigen (LcrV) protein DUF3337 PF11816.6 001155706.1_53723001_2 - 0.14 11.9 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Xan_ur_permease PF00860.18 001152243.1_53725001_3 - 4.9e-65 219.6 37.1 6.1e-65 219.3 37.1 1.1 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.3 001152243.1_53725001_3 - 0.028 14.5 0.3 0.028 14.5 0.3 3.7 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily PAP_fibrillin PF04755.10 001156981.1_53723001_3 - 3.6e-73 245.6 0.0 4.5e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 PAP_fibrillin Pkinase PF00069.23 001150614.1_53722001_3 - 0.00066 19.0 0.0 0.00089 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001150614.1_53722001_3 - 0.031 13.4 0.0 0.042 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Sugar_tr PF00083.22 001154446.1_53724001_1 - 2.2e-31 109.1 20.9 2e-28 99.3 7.2 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.14 001154446.1_53724001_1 - 1.7e-26 92.9 35.7 1.1e-23 83.6 21.0 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.12 001154446.1_53724001_1 - 3.7e-05 23.0 8.2 3.7e-05 23.0 8.2 3.3 4 0 0 4 4 4 1 Uncharacterised MFS-type transporter YbfB DUF2070 PF09843.7 001154446.1_53724001_1 - 0.79 7.8 5.1 1.3 7.1 5.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Mntp PF02659.13 001147279.1_53724001_3 - 0.04 13.5 11.9 0.096 12.3 11.9 1.6 1 0 0 1 1 1 0 Putative manganese efflux pump IBR PF01485.19 001152943.1_53724001_1 - 3.5e-12 46.2 31.3 1.1e-10 41.5 11.2 5.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.4 001152943.1_53724001_1 - 2.3e-05 24.2 5.8 2.3e-05 24.2 5.8 3.9 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.4 001152943.1_53724001_1 - 0.00019 21.1 7.4 0.00019 21.1 7.4 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001152943.1_53724001_1 - 0.0037 17.4 12.3 0.0037 17.4 12.3 4.5 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.23 001152943.1_53724001_1 - 0.0049 16.6 9.8 0.0049 16.6 9.8 4.2 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001152943.1_53724001_1 - 0.011 15.6 12.9 0.011 15.6 12.9 3.9 3 1 0 3 3 3 0 zinc-RING finger domain adh_short PF00106.23 001159027.1_53723001_3 - 5.5e-49 166.1 0.0 7.3e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001159027.1_53723001_3 - 4.2e-47 160.6 0.3 5e-47 160.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001159027.1_53723001_3 - 1.8e-06 27.8 0.2 2.6e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001159027.1_53723001_3 - 0.00022 20.6 0.0 0.00048 19.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HAUS6_N PF14661.4 001151734.1_53726001_1 - 4.5e-46 157.2 0.0 4.5e-46 157.2 0.0 3.5 3 1 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus NPV_P10 PF05531.10 001151734.1_53726001_1 - 0.047 14.0 0.3 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.10 001151734.1_53726001_1 - 0.11 11.7 2.3 0.22 10.8 2.3 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3450 PF11932.6 001151734.1_53726001_1 - 0.25 10.4 5.3 3.8 6.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-Q PF13094.4 001151734.1_53726001_1 - 1.3 9.1 20.3 0.099 12.7 4.4 3.3 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Duo1 PF08651.8 001151734.1_53726001_1 - 8.3 6.1 7.8 5.1 6.8 0.4 3.7 4 0 0 4 4 4 0 DASH complex subunit Duo1 Ribosomal_L6 PF00347.21 001156226.1_53723001_1 - 5.7e-29 100.5 0.8 3.5e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CAP_N PF01213.17 001156226.1_53723001_1 - 5.3 6.3 5.0 7.4 5.8 5.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DnaJ_CXXCXGXG PF00684.17 001150824.1_53722001_2 - 3.7e-05 23.9 0.2 0.00014 22.1 0.1 2.0 2 0 0 2 2 2 1 DnaJ central domain zinc_ribbon_9 PF14369.4 001150824.1_53722001_2 - 0.0012 18.9 2.8 0.9 9.7 0.1 2.7 3 0 0 3 3 3 2 zinc-ribbon Anti-TRAP PF15777.3 001150824.1_53722001_2 - 0.012 15.4 2.4 0.09 12.6 2.4 2.1 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn-ribbon_8 PF09723.8 001150824.1_53722001_2 - 0.05 13.6 0.2 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.5 001150824.1_53722001_2 - 0.82 9.6 2.8 7.7 6.4 0.3 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TFIIE_alpha PF02002.15 001148019.1_53725001_3 - 3.7e-11 42.7 1.7 1.3e-06 28.0 0.1 2.9 2 0 0 2 2 2 2 TFIIE alpha subunit zf-RING_2 PF13639.4 001158526.1_53722001_2 - 2.1e-11 43.8 13.7 4.2e-11 42.8 13.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 001158526.1_53722001_2 - 4.1e-08 33.2 8.2 8.5e-08 32.2 8.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001158526.1_53722001_2 - 4.6e-07 29.3 5.2 1.1e-06 28.1 5.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.23 001158526.1_53722001_2 - 1.8e-05 24.4 10.0 6.4e-05 22.6 10.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001158526.1_53722001_2 - 3.8e-05 23.3 11.6 8.5e-05 22.2 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001158526.1_53722001_2 - 0.0011 18.8 6.4 0.0021 18.0 6.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.4 001158526.1_53722001_2 - 0.0087 15.8 12.3 0.02 14.6 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001158526.1_53722001_2 - 0.0099 15.6 11.3 0.018 14.8 11.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 001158526.1_53722001_2 - 0.018 14.8 10.8 0.041 13.7 10.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.4 001158526.1_53722001_2 - 0.052 13.4 10.8 0.15 12.0 10.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.4 001158526.1_53722001_2 - 6.4 6.5 13.8 11 5.7 13.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pec_lyase_C PF00544.17 001157251.1_53724001_2 - 4.2e-20 72.1 4.8 2.5e-19 69.6 4.8 2.0 1 1 0 1 1 1 1 Pectate lyase Pec_lyase_N PF04431.11 001157251.1_53724001_2 - 5.6e-18 64.8 0.5 1.3e-17 63.6 0.5 1.7 1 0 0 1 1 1 1 Pectate lyase, N terminus Beta_helix PF13229.4 001157251.1_53724001_2 - 0.00022 21.0 4.3 0.00039 20.2 4.3 1.4 1 0 0 1 1 1 1 Right handed beta helix region Nodulin-like PF06813.11 001152707.1_53725001_1 - 7.4e-94 313.8 15.9 7.4e-94 313.8 15.9 2.4 2 1 1 3 3 3 1 Nodulin-like Pollen_allerg_1 PF01357.19 001155223.1_53723001_2 - 4.7e-30 103.3 0.0 7.9e-30 102.6 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001155223.1_53723001_2 - 8.1e-19 67.6 0.5 3.7e-18 65.4 0.1 2.3 2 1 1 3 3 3 1 Lytic transglycolase Methyltransf_3 PF01596.15 001159039.1_53722001_3 - 3.8e-81 271.2 0.0 4.5e-81 270.9 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001159039.1_53722001_3 - 6.9e-10 39.8 0.0 1.1e-09 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 001159039.1_53722001_3 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) peroxidase PF00141.21 001158788.1_53723001_1 - 2.7e-73 246.3 0.0 3.8e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Tubulin PF00091.23 001146819.1_53723001_1 - 7.3e-53 179.6 0.0 1.2e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001146819.1_53723001_1 - 4e-40 136.8 0.2 6.1e-40 136.2 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.4 001146819.1_53723001_1 - 0.00081 18.5 0.2 0.0022 17.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.4 001146819.1_53723001_1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain SMN PF06003.10 001151917.1_53723001_1 - 7.4e-06 25.3 4.1 0.008 15.3 0.1 2.9 3 0 0 3 3 3 2 Survival motor neuron protein (SMN) DUF4349 PF14257.4 001151917.1_53723001_1 - 0.012 15.0 7.5 0.021 14.2 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Homeobox PF00046.27 001156758.1_53723001_3 - 1.2e-15 57.0 5.1 2.4e-15 56.0 5.1 1.5 1 0 0 1 1 1 1 Homeobox domain HALZ PF02183.16 001156758.1_53723001_3 - 2e-09 37.4 1.3 2e-09 37.4 1.3 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper Homeobox_KN PF05920.9 001156758.1_53723001_3 - 0.0021 17.8 0.3 0.005 16.6 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF972 PF06156.11 001156758.1_53723001_3 - 0.073 13.6 0.6 0.11 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) NRBF2 PF08961.8 001156758.1_53723001_3 - 0.72 9.3 4.6 1.7 8.1 4.6 1.5 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator GRAS PF03514.12 001148273.1_53725001_3 - 2.9e-127 424.6 0.0 3.8e-127 424.2 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family TPT PF03151.14 001153967.1_53724001_3 - 1.6e-111 372.1 18.6 2e-111 371.9 18.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.18 001153967.1_53724001_3 - 9e-11 42.0 27.8 1.9e-06 28.0 8.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.9 001153967.1_53724001_3 - 0.002 17.3 11.7 0.0028 16.8 11.7 1.3 1 0 0 1 1 1 1 UAA transporter family DUF1003 PF06210.9 001153967.1_53724001_3 - 4.2 7.4 7.1 1.5 8.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) RNA_pol_Rpb4 PF03874.14 001153718.1_53723001_2 - 2.2e-20 73.1 0.0 3.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 ADK PF00406.20 001155247.1_53723001_1 - 9.4e-49 165.2 0.0 1.4e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.4 001155247.1_53723001_1 - 3.1e-37 127.9 0.1 4.2e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001155247.1_53723001_1 - 3.3e-09 37.2 0.0 4.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001155247.1_53723001_1 - 5.4e-06 26.5 0.0 9.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.15 001155247.1_53723001_1 - 5.7e-05 22.7 1.5 0.018 14.6 0.3 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_19 PF13245.4 001155247.1_53723001_1 - 0.16 12.2 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.20 001148761.1_53724001_3 - 5.3e-43 144.6 0.0 7.8e-17 60.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001148761.1_53724001_3 - 1.3e-08 34.4 0.0 5.8e-06 25.8 0.0 3.1 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001148761.1_53724001_3 - 1.5e-05 24.6 0.0 0.012 15.3 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.3 001148761.1_53724001_3 - 3e-05 23.9 0.1 0.036 14.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.9 001148761.1_53724001_3 - 6.7e-05 22.7 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif Cas_Cas2CT1978 PF09707.8 001148761.1_53724001_3 - 0.073 13.0 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) SET_assoc PF11767.6 001148761.1_53724001_3 - 0.075 12.6 0.1 15 5.1 0.0 3.1 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated His_Phos_1 PF00300.20 001154760.1_53724001_2 - 7.3e-33 113.8 0.2 1.3e-24 86.8 0.1 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) BEX PF04538.10 001148066.1_53723001_2 - 1.1 9.8 3.1 12 6.5 0.5 2.3 2 0 0 2 2 2 0 Brain expressed X-linked like family zf-RING_2 PF13639.4 001148066.1_53723001_3 - 1.2e-13 51.0 4.1 2.1e-13 50.1 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001148066.1_53723001_3 - 2.3e-10 39.9 1.1 4.1e-10 39.1 1.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001148066.1_53723001_3 - 2.5e-10 39.9 3.5 4.4e-10 39.1 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001148066.1_53723001_3 - 4e-08 33.3 6.4 1.2e-07 31.8 6.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001148066.1_53723001_3 - 6.4e-07 29.0 1.8 1.1e-06 28.3 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001148066.1_53723001_3 - 1.2e-05 25.0 1.5 2.4e-05 24.1 1.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 001148066.1_53723001_3 - 2.5e-05 23.9 1.0 4.4e-05 23.1 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001148066.1_53723001_3 - 7e-05 22.6 1.9 0.00012 21.9 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 001148066.1_53723001_3 - 0.00071 19.4 0.8 0.0014 18.6 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.6 001148066.1_53723001_3 - 0.0026 17.8 1.7 0.0061 16.6 1.7 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.4 001148066.1_53723001_3 - 0.0074 16.0 3.4 0.014 15.1 3.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.3 001148066.1_53723001_3 - 0.019 14.4 2.2 0.048 13.2 2.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.3 001148066.1_53723001_3 - 0.13 12.4 2.9 0.12 12.5 1.4 1.5 1 1 0 1 1 1 0 Zinc-ribbon like family RINGv PF12906.5 001148066.1_53723001_3 - 0.31 11.1 3.4 0.64 10.0 3.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.4 001148066.1_53723001_3 - 0.77 9.4 2.8 1.3 8.7 2.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.9 001148066.1_53723001_3 - 0.81 9.9 3.5 2.1 8.6 3.5 1.8 1 0 0 1 1 1 0 RING-like domain ZF-HD_dimer PF04770.10 001152537.1_53724001_1 - 4.9e-28 97.1 1.5 9.4e-28 96.2 1.5 1.5 1 0 0 1 1 1 1 ZF-HD protein dimerisation region DUF547 PF04784.12 001148302.1_53726001_2 - 4.6e-32 110.2 0.0 8.4e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Lzipper-MIP1 PF14389.4 001148302.1_53726001_2 - 2.6e-25 88.4 0.4 6.2e-25 87.1 0.4 1.6 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Filament_head PF04732.12 001148302.1_53726001_2 - 0.06 14.1 0.5 0.06 14.1 0.5 3.0 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region BCL_N PF04714.11 001150444.1_53723001_1 - 0.014 15.3 0.1 0.55 10.2 0.0 2.6 2 0 0 2 2 2 0 BCL7, N-terminal conserver region K_channel_TID PF07941.9 001150444.1_53723001_1 - 2.1 8.7 13.6 0.57 10.5 5.0 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain CAP_N PF01213.17 001150444.1_53723001_2 - 2.5 7.4 4.2 3.4 6.9 4.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal REV PF00424.16 001150444.1_53723001_3 - 3 7.8 8.5 5.2 7.0 8.5 1.3 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) 2OG-FeII_Oxy PF03171.18 001147340.1_53723001_3 - 5e-27 94.2 0.0 8.1e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001147340.1_53723001_3 - 3.7e-12 46.9 0.0 6.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ank_2 PF12796.5 001154512.1_53725001_3 - 5.2e-36 123.0 1.3 1.5e-09 38.2 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001154512.1_53725001_3 - 2.8e-34 116.5 13.4 9.3e-10 38.5 0.5 6.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.28 001154512.1_53725001_3 - 7.8e-34 114.5 9.9 2e-07 31.0 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.4 001154512.1_53725001_3 - 1.6e-32 111.3 4.2 7.2e-16 58.2 0.3 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 001154512.1_53725001_3 - 1.9e-27 92.2 7.1 3.7e-06 26.7 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat zf-C3HC4_3 PF13920.4 001154512.1_53725001_3 - 0.0015 18.2 8.4 0.0015 18.2 8.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001154512.1_53725001_3 - 0.0039 16.9 15.0 0.094 12.5 11.6 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001154515.1_53725001_3 - 6.4e-12 45.0 8.0 1.1e-11 44.2 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001154515.1_53725001_3 - 1.4e-08 34.3 8.2 2.6e-08 33.5 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001154515.1_53725001_3 - 1.7e-07 31.2 8.4 3.1e-07 30.4 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.4 001154515.1_53725001_3 - 1.9e-05 24.3 12.5 3.1e-05 23.6 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001154515.1_53725001_3 - 6.9e-05 22.7 6.8 0.00017 21.4 6.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001154515.1_53725001_3 - 0.00011 22.0 8.2 0.00031 20.5 8.3 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.4 001154515.1_53725001_3 - 0.0017 18.3 6.3 0.0035 17.3 6.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.4 001154515.1_53725001_3 - 0.0045 16.5 8.5 0.013 15.1 8.6 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain RAWUL PF16207.3 001154515.1_53725001_3 - 0.014 15.9 0.2 0.026 15.0 0.2 1.4 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-UDP PF14569.4 001154515.1_53725001_3 - 0.046 13.7 4.9 0.12 12.4 4.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-rbx1 PF12678.5 001154515.1_53725001_3 - 0.068 13.3 7.0 0.2 11.8 7.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain FoP_duplication PF13865.4 001154515.1_53725001_3 - 0.074 13.5 0.1 0.074 13.5 0.1 3.2 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Prok-RING_4 PF14447.4 001154515.1_53725001_3 - 0.088 12.6 12.0 1.1 9.0 12.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.4 001154515.1_53725001_3 - 0.1 12.4 6.5 0.19 11.5 6.5 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.3 001154515.1_53725001_3 - 0.14 11.8 4.2 0.26 10.9 4.2 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.3 001154515.1_53725001_3 - 0.15 12.1 6.7 0.3 11.1 6.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.6 001154515.1_53725001_3 - 0.17 11.6 3.8 0.33 10.7 3.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.3 001154515.1_53725001_3 - 0.17 11.7 8.9 0.42 10.4 8.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PRR18 PF15671.3 001157054.1_53722001_2 - 0.0058 16.4 2.5 0.0074 16.1 2.5 1.2 1 0 0 1 1 1 1 Proline-rich protein family 18 Pkinase PF00069.23 001152315.1_53725001_3 - 9e-70 234.9 0.0 1.1e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001152315.1_53725001_3 - 8.6e-52 175.8 0.0 1.2e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001152315.1_53725001_3 - 3.1e-06 26.6 0.0 7.6e-06 25.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.12 001152315.1_53725001_3 - 0.03 13.5 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001152315.1_53725001_3 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Y1_Tnp PF01797.14 001165683.1_53723001_2 - 0.044 13.8 0.8 0.11 12.5 0.2 1.9 2 0 0 2 2 2 0 Transposase IS200 like Pkinase PF00069.23 001165762.1_53724001_2 - 4.9e-49 166.9 0.0 6.6e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001165762.1_53724001_2 - 1.8e-43 148.6 0.0 2.3e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.4 001165762.1_53724001_2 - 5.1e-06 26.0 4.3 3.8e-05 23.2 1.3 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.5 001165762.1_53724001_2 - 0.00011 22.3 4.3 0.081 13.2 0.2 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Kinase-like PF14531.4 001165762.1_53724001_2 - 0.00042 19.6 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like LRR_6 PF13516.4 001165762.1_53724001_2 - 0.0065 16.3 5.5 1.7 8.8 0.6 3.8 3 0 0 3 3 3 2 Leucine Rich repeat APH PF01636.21 001165762.1_53724001_2 - 0.0076 16.1 0.0 0.021 14.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family LRR_1 PF00560.31 001165762.1_53724001_2 - 0.067 13.6 7.6 10 6.9 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat IF-2B PF01008.15 001165599.1_53725001_2 - 2.9e-82 275.9 1.2 3.3e-82 275.7 0.0 1.6 2 0 0 2 2 2 1 Initiation factor 2 subunit family GRAS PF03514.12 001174511.1_53726001_2 - 3e-80 269.8 0.0 3.7e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family SRF-TF PF00319.16 001174288.1_53724001_3 - 1e-17 63.2 0.1 1.8e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Glyphos_transf PF04464.12 001174537.1_53723001_2 - 0.053 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase CobN-Mg_chel PF02514.14 001175926.1_53725001_3 - 3.7e-150 501.7 0.0 4.5e-150 501.4 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Pex26 PF07163.10 001176648.1_53723001_3 - 0.013 14.7 0.4 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Pex26 protein PORR PF11955.6 001176648.1_53723001_3 - 0.048 12.5 0.2 0.084 11.7 0.0 1.4 2 0 0 2 2 2 0 Plant organelle RNA recognition domain CAP_N PF01213.17 001176648.1_53723001_3 - 0.049 13.0 0.6 2.2 7.6 0.1 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal HpaB_N PF11794.6 001176648.1_53723001_3 - 0.1 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Methyltransf_16 PF10294.7 001175938.1_53723001_3 - 2.5e-09 37.0 0.0 0.00086 18.9 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.4 001175938.1_53723001_3 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001175938.1_53723001_3 - 0.056 13.1 0.0 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.14 001174548.1_53725001_2 - 1.5e-48 165.4 33.5 3.4e-48 164.2 31.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Gate PF07670.12 001174548.1_53725001_2 - 0.12 12.5 4.1 2.1 8.5 0.4 2.6 1 1 0 2 2 2 0 Nucleoside recognition HSP20 PF00011.19 001175723.1_53723001_3 - 1.1e-09 38.2 0.0 2.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Bac_surface_Ag PF01103.21 001174793.1_53727001_1 - 9.8e-18 64.6 0.3 1.5e-17 63.9 0.3 1.2 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.13 001174793.1_53727001_1 - 2.7e-07 30.9 0.0 0.59 10.6 0.0 3.4 3 0 0 3 3 3 3 Surface antigen variable number repeat ADH_N PF08240.10 001176213.1_53724001_3 - 6.9e-26 90.1 0.2 1.3e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.24 001176213.1_53724001_3 - 4.7e-19 68.5 0.1 7.6e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.17 001176213.1_53724001_3 - 0.0043 16.3 0.1 0.0068 15.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.16 001176213.1_53724001_3 - 0.015 15.4 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.12 001176213.1_53724001_3 - 0.016 14.7 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.4 001176213.1_53724001_3 - 0.031 15.2 0.0 0.061 14.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RRM_DME PF15628.4 001175517.1_53725001_2 - 6.7e-48 160.9 0.1 1.3e-47 159.9 0.1 1.5 1 0 0 1 1 1 1 RRM in Demeter HhH-GPD PF00730.23 001175517.1_53725001_2 - 0.031 14.6 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.7 001175517.1_53725001_2 - 0.87 9.9 8.4 1.1 9.6 5.4 2.8 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III BSP PF04450.10 001176236.1_53723001_3 - 8.1e-27 94.2 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria Aa_trans PF01490.16 001175059.1_53724001_3 - 8.4e-114 380.3 19.3 9.9e-114 380.1 19.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase_Tyr PF07714.15 001176489.1_53723001_1 - 1.9e-43 148.5 0.0 3.2e-43 147.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001176489.1_53723001_1 - 1.8e-41 142.2 0.0 2.4e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.21 001176489.1_53723001_1 - 0.0088 15.9 0.1 0.021 14.6 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Mg_trans_NIPA PF05653.12 001174616.1_53724001_2 - 2.5e-133 443.6 18.0 3e-133 443.3 18.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.18 001174616.1_53724001_2 - 0.00014 21.9 6.2 0.00014 21.9 6.2 4.0 2 2 1 3 3 3 2 EamA-like transporter family NHL PF01436.19 001174629.1_53724001_1 - 5.7e-05 22.8 0.0 0.0051 16.7 0.0 3.3 3 0 0 3 3 3 1 NHL repeat SBBP PF06739.9 001174629.1_53724001_1 - 0.079 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Beta-propeller repeat SGL PF08450.10 001174629.1_53724001_1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Herpes_UL3 PF03369.11 001175101.1_53724001_1 - 0.18 12.2 1.4 0.49 10.8 1.4 1.7 1 0 0 1 1 1 0 Herpesvirus UL3 protein DUF2985 PF11204.6 001175101.1_53724001_2 - 8.1e-24 83.5 1.9 2.3e-23 82.0 1.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) PLAC8 PF04749.15 001175101.1_53724001_2 - 4e-18 66.1 0.7 4e-18 66.1 0.7 2.2 2 1 0 2 2 2 1 PLAC8 family Rhomboid PF01694.20 001175101.1_53724001_2 - 0.015 15.2 1.4 0.015 15.2 1.4 1.9 2 0 0 2 2 2 0 Rhomboid family RecA PF00154.19 001176740.1_53724001_2 - 4.6e-119 396.6 0.1 6e-119 396.2 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.9 001176740.1_53724001_2 - 5.8e-12 45.3 0.0 9.9e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Rad51 ATPase PF06745.11 001176740.1_53724001_2 - 7.7e-08 31.8 0.2 1.9e-06 27.2 0.0 2.4 1 1 1 2 2 2 1 KaiC ATPase_2 PF01637.16 001176740.1_53724001_2 - 0.00023 21.0 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.4 001176740.1_53724001_2 - 0.00049 19.6 1.0 0.028 13.9 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.4 001176740.1_53724001_2 - 0.00054 20.3 0.1 0.0012 19.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.4 001176740.1_53724001_2 - 0.0034 17.0 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain CobU PF02283.14 001176740.1_53724001_2 - 0.0061 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.27 001176740.1_53724001_2 - 0.028 14.7 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.4 001176740.1_53724001_2 - 0.075 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.13 001176740.1_53724001_2 - 0.078 12.1 0.0 0.23 10.6 0.0 1.6 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.4 001176740.1_53724001_2 - 0.085 12.8 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.4 001176740.1_53724001_2 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.4 001176740.1_53724001_2 - 0.1 12.7 0.0 0.37 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PPR_2 PF13041.4 001176058.1_53726001_1 - 1.3e-131 428.6 41.4 9.9e-14 51.2 0.1 16.9 4 3 13 17 17 17 16 PPR repeat family PPR PF01535.18 001176058.1_53726001_1 - 1.2e-97 313.5 36.8 1.6e-09 37.2 0.0 17.3 18 0 0 18 18 17 15 PPR repeat PPR_3 PF13812.4 001176058.1_53726001_1 - 2.5e-88 290.0 11.3 5.5e-15 55.1 0.0 12.1 6 3 7 14 14 14 13 Pentatricopeptide repeat domain PPR_1 PF12854.5 001176058.1_53726001_1 - 4.9e-82 269.2 12.4 2.9e-10 39.6 0.0 16.4 17 0 0 17 17 17 10 PPR repeat PPR_long PF17177.2 001176058.1_53726001_1 - 1.4e-41 142.1 0.1 5.2e-09 35.6 0.0 6.7 1 1 5 7 7 7 7 Pentacotripeptide-repeat region of PROPR TPR_1 PF00515.26 001176058.1_53726001_1 - 6e-07 28.9 7.0 1.3 8.9 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat MNE1 PF13762.4 001176058.1_53726001_1 - 1.2e-05 25.2 2.9 0.2 11.5 0.2 5.3 3 1 3 6 6 6 1 Mitochondrial splicing apparatus component TPR_7 PF13176.4 001176058.1_53726001_1 - 2.5e-05 23.9 1.6 11 6.2 0.0 6.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_12 PF13424.4 001176058.1_53726001_1 - 8.6e-05 22.6 3.3 21 5.4 0.0 6.9 7 2 1 8 8 7 0 Tetratricopeptide repeat TPR_2 PF07719.15 001176058.1_53726001_1 - 8.6e-05 22.2 4.9 28 5.0 0.0 7.4 9 0 0 9 9 8 0 Tetratricopeptide repeat Vps39_1 PF10366.7 001176058.1_53726001_1 - 0.0001 22.4 0.0 1.4 9.1 0.0 4.7 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.18 001176058.1_53726001_1 - 0.0048 16.6 3.2 20 4.9 0.0 6.0 5 3 2 7 7 7 0 Region in Clathrin and VPS RPM2 PF08579.9 001176058.1_53726001_1 - 0.0071 16.6 2.7 1e+02 3.2 0.1 6.3 4 2 3 7 7 6 0 Mitochondrial ribonuclease P subunit (RPM2) Katanin_con80 PF13925.4 001176058.1_53726001_1 - 0.012 15.5 0.0 14 5.6 0.0 3.6 3 0 0 3 3 3 0 con80 domain of Katanin DUF1347 PF07079.9 001176058.1_53726001_1 - 0.018 13.5 0.2 0.15 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1347) DUF3368 PF11848.6 001176058.1_53726001_1 - 0.022 14.4 0.4 28 4.4 0.0 5.4 6 1 1 7 7 7 0 Domain of unknown function (DUF3368) TPR_6 PF13174.4 001176058.1_53726001_1 - 0.03 14.8 1.7 2.5e+02 2.5 0.0 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat MRP-S27 PF10037.7 001176058.1_53726001_1 - 0.085 11.6 0.0 9.3 4.9 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 MOZART1 PF12554.6 001176058.1_53726001_1 - 0.11 12.2 0.1 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated DnaB PF00772.19 001176058.1_53726001_1 - 0.12 12.3 0.0 11 6.0 0.0 3.3 3 0 0 3 3 3 0 DnaB-like helicase N terminal domain Anoctamin PF04547.10 001175127.1_53725001_3 - 1.8e-102 343.2 16.9 2.2e-102 342.9 16.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.3 001175127.1_53725001_3 - 0.0081 15.8 0.1 2.6 7.6 0.0 2.3 1 1 1 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.7 001175127.1_53725001_3 - 3.5 6.2 9.8 0.081 11.6 1.8 2.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) zf-CCHC PF00098.21 001174891.1_53725001_1 - 3.1e-11 42.7 15.6 4.7e-06 26.3 2.4 2.9 2 0 0 2 2 2 2 Zinc knuckle RRM_1 PF00076.20 001174891.1_53725001_1 - 1.4e-09 37.5 0.0 2.4e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_5 PF14787.4 001174891.1_53725001_1 - 0.00049 19.6 12.2 0.0088 15.6 1.8 2.5 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger CLIP1_ZNF PF16641.3 001174891.1_53725001_1 - 0.085 12.6 3.2 0.18 11.6 3.2 1.6 1 0 0 1 1 1 0 CLIP1 zinc knuckle zf-CCHC_3 PF13917.4 001174891.1_53725001_1 - 0.12 12.2 9.2 2.9 7.8 2.4 2.7 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.4 001174891.1_53725001_1 - 0.33 10.6 12.3 0.82 9.3 0.6 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.4 001174891.1_53725001_1 - 4.3 7.1 13.6 0.23 11.2 2.9 2.6 2 0 0 2 2 2 0 Zinc knuckle Cu-oxidase PF00394.20 001174898.1_53724001_3 - 3.7e-48 163.5 0.0 6e-46 156.3 0.0 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.12 001174898.1_53724001_3 - 2.6e-43 146.9 4.4 1.8e-36 124.8 0.3 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.13 001174898.1_53724001_3 - 3.1e-40 136.8 0.1 3.1e-40 136.8 0.1 2.8 4 0 0 4 4 4 1 Multicopper oxidase DUF547 PF04784.12 001175388.1_53725001_1 - 2.4e-19 69.3 0.0 3.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Lzipper-MIP1 PF14389.4 001175388.1_53725001_3 - 2.1e-19 69.4 2.5 5e-19 68.2 2.5 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DUF547 PF04784.12 001175388.1_53725001_3 - 1e-07 31.9 0.1 2.3e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 betaPIX_CC PF16523.3 001175388.1_53725001_3 - 0.64 9.7 3.0 19 5.0 0.1 2.8 2 1 1 3 3 3 0 betaPIX coiled coil p450 PF00067.20 001174920.1_53724001_3 - 1.3e-95 320.8 0.0 1.6e-95 320.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase_Tyr PF07714.15 001177012.1_53723001_2 - 3e-06 26.6 0.0 4.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001177012.1_53723001_2 - 0.00021 20.6 0.0 0.0003 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pantoate_transf PF02548.13 001177012.1_53723001_3 - 7.9e-10 38.4 0.3 1.1e-09 38.0 0.3 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Sugar_tr PF00083.22 001174706.1_53724001_1 - 1.4e-100 337.1 19.5 2.3e-100 336.5 19.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001174706.1_53724001_1 - 4.7e-29 101.3 38.7 2.9e-23 82.3 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Proton_antipo_N PF00662.18 001174706.1_53724001_1 - 0.13 12.2 0.5 0.59 10.1 0.5 2.1 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Cu-oxidase PF00394.20 001176118.1_53725001_2 - 1.5e-42 145.3 1.4 3.6e-42 144.0 0.3 2.2 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.13 001176118.1_53725001_2 - 1.1e-40 138.2 3.4 1.1e-39 135.0 0.3 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.12 001176118.1_53725001_2 - 4.7e-25 87.8 0.2 2.6e-24 85.4 0.0 2.3 3 0 0 3 3 3 1 Multicopper oxidase CBM_4_9 PF02018.15 001176118.1_53725001_2 - 0.048 13.8 0.3 1.1 9.3 0.3 2.8 1 1 0 1 1 1 0 Carbohydrate binding domain Ntox30 PF15532.4 001176118.1_53725001_2 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 30 ECSCR PF15820.3 001174960.1_53722001_2 - 0.29 10.8 0.7 0.43 10.3 0.7 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF588 PF04535.10 001174960.1_53722001_3 - 3.6e-18 65.7 6.3 5.1e-18 65.2 6.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) WAK_assoc PF14380.4 001176606.1_53724001_1 - 8.8e-11 42.3 0.0 1.7e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Wall-associated receptor kinase C-terminal GUB_WAK_bind PF13947.4 001176606.1_53724001_1 - 1.7e-06 28.7 0.1 2.7e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Wall-associated receptor kinase galacturonan-binding GUB_WAK_bind PF13947.4 001176606.1_53724001_2 - 5.9e-09 36.6 0.2 5.9e-09 36.6 0.2 1.8 2 0 0 2 2 2 1 Wall-associated receptor kinase galacturonan-binding WAK_assoc PF14380.4 001176606.1_53724001_2 - 9.5e-08 32.6 0.1 2.8e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 Wall-associated receptor kinase C-terminal PPR_2 PF13041.4 001196752.1_53727001_2 - 6.8e-69 227.8 6.2 3.9e-12 46.0 0.0 12.8 8 4 6 14 14 14 10 PPR repeat family PPR PF01535.18 001196752.1_53727001_2 - 2.5e-66 215.3 14.8 1.6e-08 34.1 0.0 13.9 14 0 0 14 14 14 11 PPR repeat PPR_1 PF12854.5 001196752.1_53727001_2 - 2.2e-45 151.9 5.6 0.00013 21.5 0.7 13.4 13 1 1 14 14 14 10 PPR repeat DYW_deaminase PF14432.4 001196752.1_53727001_2 - 1.7e-39 134.5 0.1 3.3e-39 133.5 0.1 1.5 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases PPR_3 PF13812.4 001196752.1_53727001_2 - 3.3e-23 81.4 1.5 0.0014 18.5 0.0 8.7 7 3 5 12 12 12 7 Pentatricopeptide repeat domain PPR_long PF17177.2 001196752.1_53727001_2 - 5.4e-10 38.9 0.0 0.025 13.8 0.0 4.5 1 1 2 4 4 4 4 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001196752.1_53727001_2 - 0.00064 20.2 3.2 13 6.8 0.0 7.0 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.4 001196752.1_53727001_2 - 0.036 14.4 0.0 23 5.4 0.0 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat RRM_occluded PF16842.3 001196752.1_53727001_3 - 0.2 11.4 0.1 0.36 10.6 0.1 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif START PF01852.17 001196267.1_53724001_3 - 3e-08 33.2 0.0 4.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 START domain DUF1932 PF09130.9 001196267.1_53724001_3 - 0.091 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) WD40 PF00400.30 001196315.1_53724001_2 - 1.3e-05 25.7 8.3 0.023 15.4 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001196315.1_53724001_2 - 0.00015 21.9 0.0 0.6 10.3 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.6 001196315.1_53724001_2 - 0.018 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Copine PF07002.14 001196324.1_53724001_2 - 9.5e-72 240.8 0.0 1.3e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.4 001196324.1_53724001_2 - 2.3e-09 36.8 7.4 4.1e-09 36.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001196324.1_53724001_2 - 0.00013 21.7 7.8 0.00041 20.0 7.9 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.4 001196324.1_53724001_2 - 0.00051 19.7 11.6 0.001 18.7 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) vWA-TerF-like PF10138.7 001196324.1_53724001_2 - 0.00076 19.5 0.0 0.0013 18.8 0.0 1.4 1 1 0 1 1 1 1 vWA found in TerF C terminus zf-RING_2 PF13639.4 001196324.1_53724001_2 - 0.0052 16.9 10.4 0.014 15.6 10.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.4 001196324.1_53724001_2 - 0.0098 15.7 11.5 0.081 12.8 11.6 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.23 001196324.1_53724001_2 - 0.011 15.5 11.1 0.027 14.2 11.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001196324.1_53724001_2 - 0.011 15.5 6.6 0.015 15.2 4.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger TerY_C PF15616.4 001196324.1_53724001_2 - 0.35 10.9 4.2 0.67 9.9 4.2 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-C3H2C3 PF17122.3 001196324.1_53724001_2 - 0.82 9.6 8.8 1.6 8.7 3.4 2.5 2 0 0 2 2 2 0 Zinc-finger zf-4CXXC_R1 PF10497.7 001196554.1_53724001_2 - 4.6e-35 119.7 13.3 9.7e-35 118.7 13.3 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WHIM1 PF15612.4 001196554.1_53724001_2 - 4.9e-10 38.6 0.0 1.1e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Zwint PF15556.4 001196554.1_53724001_2 - 0.0014 18.0 0.8 0.0029 17.0 0.8 1.4 1 0 0 1 1 1 1 ZW10 interactor DUF3883 PF13020.4 001196554.1_53724001_2 - 0.14 12.0 0.2 0.41 10.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) Capsid-VNN PF11729.6 001196554.1_53724001_3 - 7.6 5.3 8.0 11 4.8 8.0 1.1 1 0 0 1 1 1 0 nodavirus capsid protein FPN1 PF06963.10 001196906.1_53725001_1 - 7.1e-155 515.7 28.6 8.3e-155 515.5 28.6 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Myb_DNA-binding PF00249.29 001196656.1_53723001_3 - 0.022 14.8 1.0 0.048 13.7 1.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001196656.1_53723001_3 - 0.024 14.7 2.2 0.044 13.9 2.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ribosomal_L1 PF00687.19 001196663.1_53722001_3 - 5.1e-43 147.1 4.1 6.5e-43 146.7 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.6 001196663.1_53722001_3 - 0.025 14.5 2.6 0.067 13.1 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function GRAS PF03514.12 001196729.1_53725001_1 - 1.7e-127 425.3 0.0 2.1e-127 425.0 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family DUF946 PF06101.9 001196988.1_53725001_1 - 7.2e-243 806.7 0.0 8.4e-243 806.5 0.0 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DAGK_cat PF00781.22 001175935.1_53726001_3 - 6.1e-30 103.3 0.0 8.4e-30 102.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PPR_2 PF13041.4 001279986.1_53726001_1 - 1.3e-20 73.2 11.0 8.2e-05 22.6 0.1 8.9 5 3 6 11 11 11 6 PPR repeat family PPR PF01535.18 001279986.1_53726001_1 - 4.9e-18 63.9 18.2 0.11 12.6 0.0 10.2 10 0 0 10 10 10 7 PPR repeat PPR_3 PF13812.4 001279986.1_53726001_1 - 9.7e-18 63.9 3.0 0.00085 19.2 0.0 5.9 4 2 2 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.2 001279986.1_53726001_1 - 9.9e-08 31.5 0.0 3.9e-06 26.2 0.0 2.8 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PROPR PPR_1 PF12854.5 001279986.1_53726001_1 - 2.1e-07 30.4 3.5 0.79 9.4 0.0 6.0 6 0 0 6 6 6 3 PPR repeat TPR_17 PF13431.4 001279986.1_53726001_1 - 0.04 14.2 0.1 0.34 11.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.15 001279986.1_53726001_1 - 0.18 11.9 3.0 1.8 8.8 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HSP70 PF00012.18 001301544.1_53725001_1 - 1.8e-05 23.0 0.7 2.3e-05 22.7 0.7 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.18 001301544.1_53725001_2 - 6.2e-248 823.8 8.9 7.3e-248 823.5 8.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001301544.1_53725001_2 - 7.4e-19 67.6 1.6 4.6e-16 58.4 1.6 2.4 1 1 0 1 1 1 1 MreB/Mbl protein StbA PF06406.9 001301544.1_53725001_2 - 0.0016 17.6 0.1 0.089 11.9 0.0 2.6 2 1 0 3 3 3 1 StbA protein FtsA PF14450.4 001301544.1_53725001_2 - 0.002 18.4 0.6 0.62 10.4 0.0 3.1 2 2 0 2 2 2 1 Cell division protein FtsA Hydantoinase_A PF01968.16 001301544.1_53725001_2 - 0.0044 16.2 2.1 0.44 9.6 0.1 2.8 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Glyco_hydro_9 PF00759.17 001301584.1_53724001_1 - 5.9e-137 457.3 0.0 6.8e-137 457.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 PRK PF00485.16 001154786.2_53724001_3 - 4.3e-70 235.3 0.0 5.7e-70 234.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.4 001154786.2_53724001_3 - 0.04 14.3 0.1 0.2 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain PRONE PF03759.11 001138271.2_53725001_2 - 1.4e-179 596.4 0.0 1.7e-179 596.1 0.0 1.1 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) PHB_acc PF05233.11 001157053.2_53723001_3 - 0.16 11.9 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 PHB accumulation regulatory domain MatE PF01554.16 001314069.1_53724001_3 - 2.9e-62 208.9 33.2 4.4e-31 107.6 11.6 2.4 2 0 0 2 2 2 2 MatE Put_Phosphatase PF06888.10 001154813.2_53723001_1 - 5.2e-24 84.8 0.0 7.2e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Putative Phosphatase Put_Phosphatase PF06888.10 001154813.2_53723001_2 - 6.2e-58 195.8 0.0 8.2e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.5 001154813.2_53723001_2 - 1.8e-07 31.6 0.1 2.8e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.4 001154813.2_53723001_2 - 0.7 9.8 1.7 22 4.9 1.7 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GHMP_kinases_N PF00288.24 001176665.2_53724001_1 - 6e-17 61.5 2.1 6e-17 61.5 2.1 2.5 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.11 001176665.2_53724001_1 - 6.6e-08 32.7 0.0 2.6e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.7 001176665.2_53724001_1 - 0.026 13.9 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Hexapep PF00132.22 001326395.1_53723001_3 - 3.3e-20 70.8 32.2 3.5e-06 26.4 5.4 5.3 4 1 0 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.4 001326395.1_53723001_3 - 0.029 14.0 31.1 2.2 8.0 0.1 5.8 3 2 3 6 6 6 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.10 001326395.1_53723001_3 - 1.8 7.4 4.1 2.2 7.1 0.7 2.0 1 1 0 2 2 2 0 L-fucokinase Cyclin_N PF00134.21 001326561.1_53724001_2 - 2.7e-37 127.2 2.8 3e-37 127.1 0.9 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001326561.1_53724001_2 - 2.1e-27 95.5 0.0 3.8e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DotU PF09850.7 001346812.1_53722001_1 - 0.11 12.1 0.7 0.26 10.9 0.2 1.7 2 0 0 2 2 2 0 Type VI secretion system protein DotU DUF348 PF03990.12 001149155.2_53724001_1 - 9.8 5.9 5.6 38 4.0 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF348) BURP PF03181.13 001149155.2_53724001_2 - 8.8e-56 188.8 0.0 1.2e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 BURP domain Chromo PF00385.22 001149155.2_53724001_2 - 0.18 11.6 17.5 10 5.9 0.2 6.0 2 1 4 6 6 6 0 Chromo (CHRromatin Organisation MOdifier) domain Syntaxin-18_N PF10496.7 001149155.2_53724001_2 - 0.22 11.6 8.7 18 5.5 0.3 5.5 2 1 3 5 5 5 0 SNARE-complex protein Syntaxin-18 N-terminus START PF01852.17 001149155.2_53724001_2 - 0.25 10.6 4.1 15 4.8 0.3 3.1 1 1 2 3 3 3 0 START domain Foie-gras_1 PF11817.6 136653.1_53726120_2 - 4.6e-35 121.3 0.0 6.5e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_2 PF07719.15 136653.1_53726120_2 - 0.064 13.3 2.8 23 5.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.6 136653.1_53726120_3 - 3.7e-31 108.5 0.3 5.3e-31 108.0 0.3 1.2 1 0 0 1 1 1 1 Foie gras liver health family 1 Pkinase_Tyr PF07714.15 145324.1_53722120_1 - 5.5e-27 94.5 0.0 6.8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 145324.1_53722120_1 - 2.2e-17 63.1 0.0 2.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4378 PF14309.4 001350734.1_53727001_3 - 1.6e-25 90.2 0.4 4.4e-25 88.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4378) DUF3741 PF12552.6 001350734.1_53727001_3 - 1.4e-24 85.6 3.6 3.1e-24 84.5 3.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3741) VARLMGL PF14383.4 001350734.1_53727001_3 - 4.3e-06 26.0 0.0 1.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 DUF761-associated sequence motif Presenilin PF01080.15 001146888.2_53726001_1 - 2.5e-125 418.2 3.4 3.6e-125 417.7 3.4 1.2 1 0 0 1 1 1 1 Presenilin Chromo PF00385.22 001111623.1_53723001_3 - 2.1e-17 62.6 0.1 4.6e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.17 001111623.1_53723001_3 - 5.5e-06 26.2 0.1 0.001 18.9 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Mtf2_C PF14061.4 001111623.1_53723001_3 - 0.01 15.9 0.6 0.02 14.9 0.6 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Spore_coat_CotO PF14153.4 001111623.1_53723001_3 - 0.011 15.6 6.4 0.026 14.4 6.4 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Adeno_terminal PF02459.13 001111623.1_53723001_3 - 7.6 4.7 6.2 13 3.9 6.2 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein zf-C2H2 PF00096.24 001112266.1_53723001_1 - 7.2e-17 60.7 31.2 0.00063 19.9 0.5 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001112266.1_53723001_1 - 1.2e-11 44.3 30.0 0.0079 16.8 0.6 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001112266.1_53723001_1 - 5.3e-05 23.3 8.6 0.00015 21.9 1.1 6.9 7 0 0 7 7 7 3 Zinc-finger double domain FOXP-CC PF16159.3 001112266.1_53723001_1 - 0.0059 17.1 11.4 0.19 12.2 0.1 4.5 2 1 3 5 5 5 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.3 001112266.1_53723001_1 - 0.013 15.5 14.9 9.5 6.2 0.2 4.0 3 1 0 3 3 3 0 Aberrant zinc-finger zf-C2HC_2 PF13913.4 001112266.1_53723001_1 - 0.076 12.8 6.9 42 4.1 0.1 4.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.6 001112266.1_53723001_1 - 0.14 12.3 6.3 92 3.4 0.3 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met2 PF12907.5 001112266.1_53723001_1 - 0.16 12.0 1.9 3.6 7.7 0.0 2.9 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_8 PF15909.3 001112266.1_53723001_1 - 0.38 10.9 11.7 3 8.1 1.6 2.7 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.3 001112266.1_53723001_1 - 3.6 7.3 16.2 6.1 6.6 0.3 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type Band_7 PF01145.23 001112083.1_53723001_2 - 3.8e-25 88.8 0.9 5.5e-25 88.3 0.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family APG6 PF04111.10 001112413.1_53724001_1 - 2.2e-106 355.7 8.2 2.8e-106 355.3 8.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 IncA PF04156.12 001112413.1_53724001_1 - 0.0047 16.6 16.4 0.0072 16.0 16.4 1.2 1 0 0 1 1 1 1 IncA protein Exonuc_VII_L PF02601.13 001112413.1_53724001_1 - 0.0051 16.3 0.5 0.0068 15.9 0.5 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Nup88 PF10168.7 001112413.1_53724001_1 - 0.02 12.6 5.8 0.03 12.0 5.8 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF342 PF03961.11 001112413.1_53724001_1 - 0.036 12.5 5.9 0.05 12.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PspA_IM30 PF04012.10 001112413.1_53724001_1 - 0.043 13.2 8.6 0.062 12.7 8.6 1.2 1 0 0 1 1 1 0 PspA/IM30 family AAA_11 PF13086.4 001112413.1_53724001_1 - 0.66 9.5 6.0 0.99 8.9 6.0 1.2 1 0 0 1 1 1 0 AAA domain SpecificRecomb PF10136.7 001112413.1_53724001_1 - 0.72 8.0 3.0 0.98 7.5 3.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF3450 PF11932.6 001112413.1_53724001_1 - 1.8 7.7 12.2 1.3 8.1 9.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CCDC-167 PF15188.4 001112413.1_53724001_1 - 1.8 8.8 15.2 0.27 11.5 8.8 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4140 PF13600.4 001112413.1_53724001_1 - 8.1 6.8 8.6 20 5.6 4.8 2.5 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Aldedh PF00171.20 001112421.1_53725001_2 - 5.7e-180 598.6 0.0 6.6e-180 598.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SQAPI PF16845.3 001112478.1_53722001_2 - 1.4e-27 95.7 0.0 1.9e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor Cystatin PF00031.19 001112478.1_53722001_2 - 2.7e-06 27.4 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain PP1 PF07430.9 001112478.1_53722001_2 - 0.019 14.9 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Pkinase PF00069.23 001111933.1_53723001_3 - 5.4e-67 225.8 0.0 6.5e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001111933.1_53723001_3 - 5.4e-38 130.6 0.0 7.1e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001111933.1_53723001_3 - 0.00072 18.8 0.3 0.003 16.8 0.3 2.0 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.9 001111933.1_53723001_3 - 0.026 13.4 0.0 0.073 12.0 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.21 001111933.1_53723001_3 - 0.026 14.3 0.1 0.083 12.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.20 001111933.1_53723001_3 - 0.11 12.0 0.2 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 RIO1 family NAD_binding_6 PF08030.10 001112495.1_53727001_2 - 1.4e-51 174.6 0.0 2.4e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NADPH_Ox PF08414.8 001112495.1_53727001_2 - 5.3e-38 129.2 2.6 1.1e-37 128.2 2.6 1.6 1 0 0 1 1 1 1 Respiratory burst NADPH oxidase FAD_binding_8 PF08022.10 001112495.1_53727001_2 - 6.4e-33 113.0 0.0 1.3e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.17 001112495.1_53727001_2 - 3.4e-21 75.5 3.1 3.4e-21 75.5 3.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.4 001112495.1_53727001_2 - 1.5e-06 28.5 3.8 0.0006 20.1 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001112495.1_53727001_2 - 7.9e-05 21.8 1.1 0.0061 15.9 0.4 3.5 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.4 001112495.1_53727001_2 - 0.0023 17.6 0.4 0.015 15.1 0.0 2.6 4 0 0 4 4 4 1 EF-hand domain MPS2 PF17060.3 001112495.1_53727001_2 - 0.019 14.1 0.3 0.034 13.3 0.3 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 EF-hand_5 PF13202.4 001112495.1_53727001_2 - 0.035 13.5 3.2 0.068 12.6 0.4 2.6 2 0 0 2 2 2 0 EF hand Glyoxalase PF00903.23 001111747.1_53723001_1 - 2.6e-36 124.5 0.1 6.9e-22 77.9 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.4 001111747.1_53723001_1 - 4.5e-13 49.3 0.0 1.4e-06 28.4 0.0 3.3 1 1 2 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.4 001111747.1_53723001_1 - 0.00031 20.7 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_3 PF13468.4 001111747.1_53723001_1 - 0.0061 16.6 0.0 0.86 9.6 0.0 3.2 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase_2 PF12681.5 001111747.1_53723001_1 - 0.023 14.5 0.0 2.1 8.2 0.0 2.9 3 1 0 3 3 3 0 Glyoxalase-like domain TPR_8 PF13181.4 001111747.1_53723001_1 - 0.025 14.6 0.0 0.6 10.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.4 001111747.1_53723001_1 - 0.033 14.1 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.26 001111747.1_53723001_1 - 0.077 12.7 0.1 4.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MEKHLA PF08670.9 001112524.1_53726001_2 - 1.5e-49 167.4 0.0 2.8e-49 166.5 0.0 1.5 1 0 0 1 1 1 1 MEKHLA domain START PF01852.17 001112524.1_53726001_2 - 7.4e-49 165.9 0.0 1.3e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 START domain Homeobox PF00046.27 001112524.1_53726001_2 - 3.1e-16 58.8 0.1 7e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain bZIP_1 PF00170.19 001112524.1_53726001_2 - 0.05 13.6 9.8 0.1 12.5 9.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor Homeobox_KN PF05920.9 001112524.1_53726001_2 - 0.061 13.1 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain GIT_CC PF16559.3 001112524.1_53726001_2 - 0.17 11.8 6.7 0.36 10.7 6.7 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.16 001112524.1_53726001_2 - 0.23 11.5 1.3 0.5 10.5 1.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper KxDL PF10241.7 001112524.1_53726001_2 - 0.24 11.6 9.1 0.58 10.3 9.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein IncA PF04156.12 001112524.1_53726001_2 - 2.2 7.9 4.7 3.5 7.2 4.7 1.3 1 0 0 1 1 1 0 IncA protein SET PF00856.26 001112183.1_53723001_1 - 5.4e-22 78.8 1.8 1.3e-21 77.6 0.2 2.3 2 1 0 2 2 2 1 SET domain RicinB_lectin_2 PF14200.4 001112183.1_53723001_1 - 0.022 15.3 0.0 0.042 14.5 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like WRC PF08879.8 001112574.1_53723001_3 - 1.1e-20 72.9 10.0 2e-20 72.1 10.0 1.4 1 0 0 1 1 1 1 WRC QLQ PF08880.9 001112574.1_53723001_3 - 2.9e-14 52.4 0.2 2.9e-14 52.4 0.2 1.8 2 0 0 2 2 2 1 QLQ zf-C3Hc3H PF13891.4 001112574.1_53723001_3 - 0.0072 16.5 0.4 0.018 15.3 0.4 1.7 1 0 0 1 1 1 1 Potential DNA-binding domain DEAD PF00270.27 001111404.1_53724001_2 - 5e-40 137.0 0.0 8.2e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001111404.1_53724001_2 - 5.6e-30 103.8 0.1 1.7e-28 99.0 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.13 001111404.1_53724001_2 - 1.4e-05 25.1 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.4 001111404.1_53724001_2 - 0.0092 15.2 0.7 0.025 13.8 0.0 2.0 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.4 001111404.1_53724001_2 - 0.064 13.4 0.1 0.25 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.4 001111404.1_53724001_2 - 0.081 13.1 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain FUSC-like PF12805.5 001111404.1_53724001_2 - 0.18 10.7 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF2780 PF11075.6 001111404.1_53724001_2 - 0.2 11.6 0.0 0.46 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) PBP PF01161.18 001112794.1_53722001_2 - 5.7e-14 52.4 0.0 7.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_transf_20 PF00982.19 001130121.2_53726001_1 - 1.1e-181 604.5 0.0 1.4e-181 604.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.14 001130121.2_53726001_1 - 1e-51 175.2 0.0 2.2e-51 174.1 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.18 001130121.2_53726001_1 - 0.011 15.2 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001130121.2_53726001_1 - 0.012 15.9 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.9 001130121.2_53726001_1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.4 001130121.2_53726001_1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 MFS_1 PF07690.14 001137429.1_53724001_2 - 4.6e-32 111.2 18.3 4.6e-32 111.2 18.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.22 001137429.1_53724001_2 - 9.1e-11 41.1 2.1 9.1e-11 41.1 2.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Transferase PF02458.13 001137177.1_53724001_1 - 5e-39 134.1 0.0 6.2e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Transferase family Aldo_ket_red PF00248.19 001136674.1_53723001_2 - 5.9e-75 252.0 0.0 7.5e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SapB_1 PF05184.13 001136679.1_53723001_2 - 0.09 12.7 2.6 35 4.4 0.0 3.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF3456 PF11938.6 001136679.1_53723001_2 - 3.4 8.0 21.9 0.17 12.3 7.4 3.7 2 1 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP Myb_DNA-bind_3 PF12776.5 001136947.1_53724001_1 - 1.7e-18 67.1 0.6 3.2e-18 66.2 0.6 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.4 001136947.1_53724001_1 - 0.00024 21.3 0.7 0.00049 20.3 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.12 001136947.1_53724001_1 - 0.051 14.1 0.1 0.14 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Myb_DNA-binding PF00249.29 001136964.1_53723001_1 - 1.4e-19 69.9 1.8 5e-15 55.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001136964.1_53723001_1 - 4.9e-11 42.6 1.5 8.6e-08 32.2 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.29 001136964.1_53723001_3 - 0.00028 20.8 0.0 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2 PF00096.24 001136965.1_53724001_1 - 0.003 17.8 1.6 0.0051 17.1 0.0 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type E2F_CC-MB PF16421.3 001137480.1_53724001_2 - 6.1e-34 116.2 0.1 9.7e-34 115.6 0.1 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.18 001137480.1_53724001_2 - 1.7e-23 82.3 0.0 2.8e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.17 001137480.1_53724001_2 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Shikimate_DH PF01488.18 001136978.1_53725001_2 - 1.6e-43 147.9 0.4 3.7e-43 146.8 0.4 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_N PF05201.13 001136978.1_53725001_2 - 1.2e-42 144.8 0.0 4e-42 143.1 0.0 2.0 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, N-terminal domain GlutR_dimer PF00745.18 001136978.1_53725001_2 - 5.4e-28 97.1 0.3 1.5e-27 95.7 0.3 1.9 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.15 001136978.1_53725001_2 - 6e-08 33.0 0.3 2.8e-07 30.9 0.1 2.3 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.13 001136978.1_53725001_2 - 6.7e-06 26.2 0.1 1.5e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.4 001136978.1_53725001_2 - 4e-05 23.5 0.9 0.0001 22.2 0.9 1.8 1 1 0 1 1 1 1 NAD(P)H-binding OCD_Mu_crystall PF02423.13 001136978.1_53725001_2 - 0.00016 20.6 0.2 0.00039 19.3 0.2 1.6 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.16 001136978.1_53725001_2 - 0.00023 21.3 0.0 0.0007 19.7 0.0 1.9 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.12 001136978.1_53725001_2 - 0.00062 19.3 0.5 0.0018 17.8 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.17 001136978.1_53725001_2 - 0.001 18.3 0.0 0.0022 17.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.16 001136978.1_53725001_2 - 0.0011 19.1 0.1 0.0035 17.5 0.1 2.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.14 001136978.1_53725001_2 - 0.0034 16.9 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.4 001136978.1_53725001_2 - 0.0099 16.2 0.3 0.034 14.5 0.3 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding KR PF08659.8 001136978.1_53725001_2 - 0.0099 15.7 0.1 0.034 13.9 0.1 2.0 1 1 0 1 1 1 1 KR domain ThiF PF00899.19 001136978.1_53725001_2 - 0.012 14.8 1.6 0.1 11.8 0.1 2.2 2 0 0 2 2 2 0 ThiF family Glu_dehyd_C PF16912.3 001136978.1_53725001_2 - 0.015 14.6 0.2 0.029 13.7 0.2 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus GFO_IDH_MocA PF01408.20 001136978.1_53725001_2 - 0.076 13.7 0.1 0.27 11.9 0.1 2.0 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Gp_dh_N PF00044.22 001136978.1_53725001_2 - 0.084 13.1 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain FANCI_S1-cap PF14674.4 001136978.1_53725001_2 - 0.11 12.4 0.1 0.79 9.7 0.0 2.3 2 0 0 2 2 2 0 FANCI solenoid 1 cap PTH2 PF01981.14 001136978.1_53725001_2 - 0.87 9.7 4.2 0.27 11.4 0.1 2.2 3 0 0 3 3 2 0 Peptidyl-tRNA hydrolase PTH2 RRM_1 PF00076.20 001136729.1_53723001_1 - 6.9e-22 76.9 0.0 1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001136729.1_53723001_1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.3 001136729.1_53723001_1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif dsrm PF00035.24 001136731.1_53723001_2 - 9.1e-25 87.0 1.8 5.1e-15 55.8 0.3 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif GST_N_3 PF13417.4 001136734.1_53723001_1 - 1.9e-14 53.7 0.1 3.3e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.22 001136734.1_53723001_1 - 3.5e-11 43.0 0.3 6.5e-11 42.2 0.3 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.2 001136734.1_53723001_1 - 1.5e-10 41.6 0.0 2.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.4 001136734.1_53723001_1 - 4.6e-09 36.4 0.0 8.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001136734.1_53723001_1 - 3.5e-05 23.9 0.0 7.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001136734.1_53723001_1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001136734.1_53723001_1 - 0.0023 18.0 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.7 001136734.1_53723001_1 - 0.0057 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.2 001136734.1_53723001_1 - 0.039 13.6 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001136734.1_53723001_1 - 0.089 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4578 PF15147.4 001136734.1_53723001_2 - 0.65 10.7 2.7 1.1 9.9 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) SR-25 PF10500.7 001136991.1_53725001_2 - 0.17 11.3 15.5 0.24 10.9 15.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Actin PF00022.17 001136991.1_53725001_3 - 4.2e-148 493.2 0.0 1.3e-147 491.5 0.0 1.8 1 1 0 1 1 1 1 Actin UQ_con PF00179.24 001137242.1_53723001_2 - 3.2e-45 153.1 0.0 4.1e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001137242.1_53723001_2 - 0.00049 19.7 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.9 001137242.1_53723001_2 - 0.0067 15.9 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 zf-RING_2 PF13639.4 001137500.1_53722001_3 - 3.4e-15 55.9 5.7 9.7e-15 54.4 5.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001137500.1_53722001_3 - 1.8e-12 46.6 2.8 4.2e-12 45.4 2.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001137500.1_53722001_3 - 1.4e-08 34.3 4.9 1.4e-08 34.3 4.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001137500.1_53722001_3 - 8.1e-08 32.3 8.0 8.1e-08 32.3 8.0 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001137500.1_53722001_3 - 8.3e-07 28.6 4.0 8.3e-07 28.6 4.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001137500.1_53722001_3 - 2e-06 27.6 2.4 5.1e-06 26.3 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001137500.1_53722001_3 - 4.2e-06 26.5 3.5 4.2e-06 26.5 3.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 001137500.1_53722001_3 - 1.2e-05 25.1 0.4 2.9e-05 23.9 0.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.4 001137500.1_53722001_3 - 0.00019 21.1 3.5 0.00019 21.1 3.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001137500.1_53722001_3 - 0.00031 20.4 4.1 0.001 18.7 4.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.4 001137500.1_53722001_3 - 0.002 17.9 0.4 0.002 17.9 0.4 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 FANCL_C PF11793.6 001137500.1_53722001_3 - 0.0021 18.1 2.0 0.0059 16.6 2.0 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.3 001137500.1_53722001_3 - 0.0025 17.3 4.7 0.0025 17.3 4.7 2.0 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type DUF4381 PF14316.4 001137500.1_53722001_3 - 0.013 15.6 0.4 0.021 15.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-RING-like PF08746.9 001137500.1_53722001_3 - 0.056 13.6 2.3 0.056 13.6 2.3 2.4 2 0 0 2 2 2 0 RING-like domain Reticulon PF02453.15 001137006.1_53723001_2 - 1.6e-55 187.2 1.1 2e-55 186.9 1.1 1.1 1 0 0 1 1 1 1 Reticulon Asn_synthase PF00733.19 001137543.1_53724001_2 - 3.6e-96 322.8 2.5 6.7e-93 312.0 2.5 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.4 001137543.1_53724001_2 - 2e-38 131.0 0.0 3.2e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001137543.1_53724001_2 - 1.3e-26 93.3 0.0 2.1e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.6 001137543.1_53724001_2 - 7.9e-14 51.5 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein DUF1933 PF09147.8 001137543.1_53724001_2 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1933) NAD_synthase PF02540.15 001137543.1_53724001_2 - 0.01 14.9 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.14 001137543.1_53724001_2 - 0.087 11.5 0.0 0.19 10.3 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Serinc PF03348.13 001137018.1_53724001_3 - 3e-117 392.0 7.3 4.4e-117 391.5 7.3 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3671 PF12420.6 001137018.1_53724001_3 - 4.7 7.2 5.4 10 6.1 0.4 2.9 2 2 0 2 2 2 0 Protein of unknown function YfhO PF09586.8 001137018.1_53724001_3 - 9.8 4.1 8.7 0.51 8.4 2.3 1.7 1 1 1 2 2 2 0 Bacterial membrane protein YfhO FAD_binding_6 PF00970.22 001136769.1_53723001_3 - 1.3e-33 115.1 0.1 2.8e-33 114.1 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.19 001136769.1_53723001_3 - 1.8e-31 108.9 0.0 2.7e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.10 001136769.1_53723001_3 - 0.00057 19.9 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Glyco_hydro_100 PF12899.5 001137021.1_53725001_1 - 6e-216 717.0 0.0 7e-216 716.8 0.0 1.0 1 0 0 1 1 1 1 Alkaline and neutral invertase GDE_C PF06202.12 001137021.1_53725001_1 - 4.6e-05 22.4 0.0 0.0026 16.6 0.1 2.7 2 1 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Peptidase_C1 PF00112.21 001137031.1_53723001_2 - 1.5e-74 250.6 4.1 1.5e-74 250.6 4.1 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001137031.1_53723001_2 - 1.7e-16 60.2 2.1 2.7e-16 59.6 2.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 001137031.1_53723001_2 - 0.0016 17.1 0.3 0.73 8.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family TPP_enzyme_N PF02776.16 001137312.1_53724001_2 - 6.3e-42 143.0 1.6 8e-41 139.4 0.6 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.20 001137312.1_53724001_2 - 7.4e-33 113.1 0.0 1.4e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.19 001137312.1_53724001_2 - 1.9e-27 95.8 0.0 5.4e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.14 001137312.1_53724001_2 - 0.01 15.5 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit RRM_1 PF00076.20 001137073.1_53724001_3 - 9.2e-24 82.9 0.0 1.6e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAM2 PF07145.13 001137073.1_53724001_3 - 4.2e-08 32.2 0.0 2.3e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 Ataxin-2 C-terminal region RRM_occluded PF16842.3 001137073.1_53724001_3 - 0.023 14.4 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.4 001137073.1_53724001_3 - 0.12 12.5 0.2 15 5.6 0.0 3.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Sporozoite_P67 PF05642.9 001137073.1_53724001_3 - 1.1 7.1 7.4 1.4 6.7 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_PAP PF03325.11 001137073.1_53724001_3 - 2.1 7.3 11.1 3.1 6.7 11.1 1.2 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein PC-Esterase PF13839.4 001137337.1_53725001_2 - 1.1e-90 304.1 0.4 1.4e-90 303.8 0.4 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.4 001137337.1_53725001_2 - 3.9e-20 71.7 7.9 9e-20 70.6 7.9 1.7 1 0 0 1 1 1 1 PMR5 N terminal Domain Exostosin PF03016.13 001136587.1_53724001_1 - 2.5e-71 240.2 0.0 3.4e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Exostosin family PsbT PF01405.15 001136587.1_53724001_3 - 0.055 13.2 1.3 0.1 12.3 1.3 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre T protein peroxidase PF00141.21 001136589.1_53723001_1 - 2.1e-71 240.1 0.1 2.7e-71 239.8 0.1 1.1 1 0 0 1 1 1 1 Peroxidase FTCD_C PF04961.10 001136589.1_53723001_1 - 0.15 11.7 1.5 0.3 10.7 1.5 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase TPR_12 PF13424.4 001137354.1_53726001_2 - 3.8e-42 142.3 20.4 8.4e-11 41.9 0.2 7.8 3 2 6 10 10 9 7 Tetratricopeptide repeat TPR_10 PF13374.4 001137354.1_53726001_2 - 3.2e-34 115.7 9.8 5.3e-07 29.2 0.0 9.1 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_1 PF00515.26 001137354.1_53726001_2 - 3.3e-26 89.8 15.9 6.7e-06 25.6 0.0 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.15 001137354.1_53726001_2 - 3.4e-26 89.1 12.1 0.00016 21.4 0.0 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.4 001137354.1_53726001_2 - 7.1e-24 81.9 15.8 3.6e-05 23.5 0.0 9.3 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_7 PF13176.4 001137354.1_53726001_2 - 2.4e-19 67.7 7.0 0.021 14.7 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.4 001137354.1_53726001_2 - 3.2e-12 46.6 7.6 0.0047 17.3 0.0 6.3 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.4 001137354.1_53726001_2 - 3.8e-10 39.6 13.0 2.9 8.8 0.0 10.3 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_16 PF13432.4 001137354.1_53726001_2 - 5e-10 39.8 5.7 0.49 11.0 0.1 6.7 6 2 0 6 6 6 2 Tetratricopeptide repeat SNAP PF14938.4 001137354.1_53726001_2 - 4e-09 36.2 8.1 3.2e-06 26.7 0.3 3.6 2 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_11 PF13414.4 001137354.1_53726001_2 - 8.1e-09 34.9 5.9 0.00047 19.7 0.1 6.4 7 0 0 7 7 7 1 TPR repeat DUF2225 PF09986.7 001137354.1_53726001_2 - 7.1e-07 29.0 4.6 0.00088 18.9 0.4 2.8 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.7 001137354.1_53726001_2 - 2.4e-05 24.1 3.3 3.3e-05 23.6 0.8 2.5 3 1 1 4 4 3 1 Tetratricopeptide repeat-like domain RPN7 PF10602.7 001137354.1_53726001_2 - 8e-05 22.2 3.6 0.018 14.6 2.0 4.2 3 1 0 3 3 3 1 26S proteasome subunit RPN7 14-3-3 PF00244.18 001137354.1_53726001_2 - 0.00028 20.3 1.3 0.58 9.5 0.0 3.0 3 0 0 3 3 3 2 14-3-3 protein TPR_6 PF13174.4 001137354.1_53726001_2 - 0.00036 20.8 13.0 2.4 8.8 0.0 7.2 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_17 PF13431.4 001137354.1_53726001_2 - 0.0018 18.4 0.2 49 4.5 0.0 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF4810 PF16068.3 001137354.1_53726001_2 - 0.0054 17.1 2.3 0.29 11.6 0.5 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4810) Fis1_TPR_C PF14853.4 001137354.1_53726001_2 - 0.014 15.3 7.9 0.016 15.2 0.4 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Vps39_1 PF10366.7 001137354.1_53726001_2 - 0.052 13.7 0.1 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_4 PF07721.12 001137354.1_53726001_2 - 0.094 13.3 8.2 17 6.2 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat HEPN PF05168.12 001137354.1_53726001_2 - 0.13 12.3 0.8 0.7 9.9 0.1 2.4 1 1 1 2 2 2 0 HEPN domain MIT PF04212.16 001137354.1_53726001_2 - 0.4 10.7 8.5 3.2 7.8 0.1 5.2 5 1 1 6 6 4 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.6 001137354.1_53726001_2 - 2.3 6.8 6.4 0.71 8.5 0.1 3.0 3 1 0 4 4 4 0 NMDA receptor-regulated protein 1 MFS_1 PF07690.14 001137105.1_53725001_2 - 1.1e-61 208.6 36.4 5.8e-61 206.2 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.11 001137105.1_53725001_2 - 1.4e-06 26.9 3.8 3.1e-06 25.8 3.8 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector UFD1 PF03152.12 001136859.1_53725001_1 - 9.2e-44 148.8 0.0 1.6e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf-TRAF PF02176.16 001136859.1_53725001_1 - 0.00078 20.0 27.9 0.0052 17.3 2.5 4.0 2 1 2 4 4 4 3 TRAF-type zinc finger Sgf11 PF08209.9 001136859.1_53725001_1 - 0.022 14.2 9.3 2.9 7.4 0.3 4.0 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) DDRGK PF09756.7 001136859.1_53725001_1 - 3.2 7.2 12.8 20 4.6 13.8 1.7 2 0 0 2 2 2 0 DDRGK domain DUF1682 PF07946.12 001136859.1_53725001_1 - 8.5 5.3 8.3 13 4.7 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SET PF00856.26 001137121.1_53724001_1 - 7.6e-16 58.8 0.0 2.4e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 SET domain TPR_9 PF13371.4 001137121.1_53724001_1 - 0.00061 19.8 7.4 0.0022 18.0 7.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.26 001137121.1_53724001_1 - 0.015 14.9 1.1 0.18 11.5 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.4 001137121.1_53724001_1 - 0.074 13.6 12.9 0.18 12.4 12.9 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.15 001137121.1_53724001_1 - 2.5 8.3 9.8 0.31 11.1 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PRIMA1 PF16101.3 001137124.1_53722001_2 - 0.45 10.4 5.4 0.72 9.8 5.4 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 V-SNARE_C PF12352.6 001137124.1_53722001_3 - 1.7e-19 69.7 4.4 1.7e-19 69.7 4.4 3.4 2 1 2 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.13 001137124.1_53722001_3 - 6.8e-16 58.3 4.4 8e-16 58.1 0.4 2.6 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.11 001137124.1_53722001_3 - 3.4e-05 23.5 0.6 8.2e-05 22.3 0.1 1.8 2 1 0 2 2 2 1 Sec20 Prominin PF05478.9 001137124.1_53722001_3 - 0.00076 17.4 0.5 0.0021 16.0 0.4 1.7 1 1 0 1 1 1 1 Prominin Pox_EPC_I2-L1 PF12575.6 001137124.1_53722001_3 - 0.17 12.0 0.4 0.29 11.3 0.4 1.3 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 KxDL PF10241.7 001137124.1_53722001_3 - 0.76 10.0 5.9 1.8 8.8 1.3 2.9 2 1 0 3 3 3 0 Uncharacterized conserved protein HR1 PF02185.14 001137124.1_53722001_3 - 5.5 7.0 10.4 1.1 9.2 1.8 3.0 2 1 0 2 2 2 0 Hr1 repeat Reticulon PF02453.15 001137131.1_53723001_1 - 8e-53 178.4 6.7 1e-52 178.1 6.7 1.1 1 0 0 1 1 1 1 Reticulon Dynamin_N PF00350.21 001136892.1_53726001_1 - 3.2e-33 115.0 0.0 5.1e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.21 001136892.1_53726001_1 - 8.4e-06 25.7 0.0 2.5e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.14 001136892.1_53726001_1 - 0.035 13.3 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 AIG1 family AAA_28 PF13521.4 001136892.1_53726001_1 - 0.14 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DBD_Tnp_Mut PF03108.13 001137152.1_53725001_1 - 1.1e-18 66.6 0.8 2e-18 65.8 0.2 1.7 2 0 0 2 2 2 1 MuDR family transposase MULE PF10551.7 001137152.1_53725001_1 - 1.7e-12 47.5 0.0 3.7e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.15 001137152.1_53725001_1 - 1.6e-09 37.1 0.2 4.7e-09 35.6 0.1 1.9 2 0 0 2 2 2 1 SWIM zinc finger Transposase_mut PF00872.16 001137152.1_53725001_1 - 0.14 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family Peptidase_M50 PF02163.20 001137758.1_53725001_1 - 1.6e-07 30.8 4.5 0.00045 19.4 0.0 2.5 1 1 1 2 2 2 2 Peptidase family M50 Iwr1 PF08574.8 001138914.1_53723001_3 - 0.0044 17.9 12.1 0.0044 17.9 12.1 3.5 3 1 1 4 4 4 1 Transcription factor Iwr1 DUF892 PF05974.10 001138914.1_53723001_3 - 0.1 12.4 0.7 0.2 11.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) MscS_porin PF12795.5 001138686.1_53724001_3 - 0.009 15.4 1.6 0.017 14.5 1.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Spc7 PF08317.9 001138686.1_53724001_3 - 0.013 14.3 0.5 0.02 13.6 0.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein KELK PF15796.3 001138686.1_53724001_3 - 0.049 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GAS PF13851.4 001138686.1_53724001_3 - 0.092 12.0 0.4 0.17 11.1 0.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.9 001138686.1_53724001_3 - 0.13 12.7 1.0 0.22 12.0 0.2 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Methyltransf_2 PF00891.16 001138233.1_53723001_2 - 1.1e-53 181.6 0.0 1.5e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.9 001138233.1_53723001_2 - 2.2e-05 24.3 0.2 4.9e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.3 001138233.1_53723001_2 - 0.0027 17.5 0.1 0.0048 16.7 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_31 PF13847.4 001138233.1_53723001_2 - 0.011 15.4 0.0 0.037 13.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.4 001138233.1_53723001_2 - 0.017 15.7 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.10 001138233.1_53723001_2 - 0.017 15.7 0.1 0.13 12.9 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain Polysacc_synt_4 PF04669.11 001138922.1_53723001_2 - 7e-71 237.6 0.0 1.1e-70 237.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis Adaptin_N PF01602.18 001138468.1_53723001_1 - 0.0012 17.4 0.2 0.35 9.3 0.2 2.1 2 0 0 2 2 2 2 Adaptin N terminal region FKBP_C PF00254.26 001138245.1_53723001_3 - 8.5e-15 54.7 0.0 1.5e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.26 001138245.1_53723001_3 - 8.4e-14 50.6 3.6 0.0042 16.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.15 001138245.1_53723001_3 - 1.3e-12 46.7 1.1 0.0016 18.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.4 001138245.1_53723001_3 - 8.2e-09 34.9 3.5 0.00073 19.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.4 001138245.1_53723001_3 - 1.3e-07 31.1 0.6 0.0013 18.3 0.2 3.3 2 1 1 3 3 3 2 TPR repeat TPR_6 PF13174.4 001138245.1_53723001_3 - 0.00013 22.3 2.4 0.66 10.6 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.7 001138245.1_53723001_3 - 0.00096 18.8 2.6 0.22 11.1 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_14 PF13428.4 001138245.1_53723001_3 - 0.0013 19.3 0.2 5 8.1 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.4 001138245.1_53723001_3 - 0.0017 18.7 1.8 0.036 14.4 0.9 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.4 001138245.1_53723001_3 - 0.0059 16.7 2.9 0.33 11.1 0.1 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001138245.1_53723001_3 - 0.011 15.8 1.3 0.1 12.7 0.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.4 001138245.1_53723001_3 - 0.025 14.5 0.6 31 4.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.4 001138245.1_53723001_3 - 0.066 13.8 12.1 0.096 13.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.4 001138245.1_53723001_3 - 0.15 11.9 1.0 11 5.9 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.20 001139396.1_53723001_2 - 2.2e-13 49.5 0.1 3.9e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 LSM domain GARP PF16731.3 001137786.1_53723001_1 - 0.0047 16.5 7.6 0.0068 16.0 7.6 1.1 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma DUF1804 PF08822.9 001137786.1_53723001_1 - 0.01 15.7 1.3 0.016 15.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DUF3450 PF11932.6 001137786.1_53723001_1 - 0.017 14.3 0.4 0.022 13.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EspB PF05802.9 001137786.1_53723001_1 - 0.078 12.0 5.3 0.11 11.5 5.3 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF948 PF06103.9 001137786.1_53723001_1 - 0.094 12.8 5.3 0.88 9.7 5.3 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RecG_N PF17190.2 001137786.1_53723001_1 - 0.12 13.0 1.1 1.7 9.3 0.1 2.1 1 1 1 2 2 2 0 RecG N-terminal helical domain FlgN PF05130.10 001137786.1_53723001_1 - 0.12 12.8 0.3 0.18 12.2 0.3 1.2 1 0 0 1 1 1 0 FlgN protein WXG100 PF06013.10 001137786.1_53723001_1 - 0.64 10.1 2.9 2.1 8.5 0.3 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG PMC2NT PF08066.10 001137786.1_53723001_1 - 0.72 10.4 3.9 4.8 7.8 3.9 2.1 1 1 0 1 1 1 0 PMC2NT (NUC016) domain DUF1664 PF07889.10 001137786.1_53723001_1 - 1.6 8.6 3.9 5.1 7.0 3.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Pup PF05639.9 001137786.1_53723001_1 - 7.1 7.5 9.7 0.92 10.3 3.4 2.1 2 0 0 2 2 2 0 Pup-like protein Mannosyl_trans PF05007.11 001138939.1_53724001_3 - 6.9e-74 248.8 27.1 1.6e-72 244.3 27.1 2.2 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.11 001138939.1_53724001_3 - 2.2e-13 49.9 22.2 3.9e-13 49.1 22.2 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U HLH PF00010.24 001139407.1_53724001_1 - 9.1e-11 41.4 0.0 1.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nro1 PF12753.5 001139407.1_53724001_1 - 0.048 12.5 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF3678 PF12435.6 001139407.1_53724001_1 - 0.35 10.0 10.0 0.94 8.6 5.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3678) EamA PF00892.18 001138483.1_53723001_3 - 2.1e-29 102.3 37.9 5e-17 62.2 13.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF3185 PF11381.6 001138483.1_53723001_3 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3185) NTP_transferase PF00483.21 001139410.1_53724001_2 - 1e-12 48.0 0.0 2.6e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001139410.1_53724001_2 - 7.9e-12 45.7 3.8 1.4e-11 44.9 3.8 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001139410.1_53724001_2 - 2.5e-11 42.7 13.1 0.00048 19.6 0.0 4.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.3 001139410.1_53724001_2 - 0.0011 17.0 3.4 0.0017 16.4 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.17 001139410.1_53724001_2 - 0.026 14.2 0.1 0.051 13.2 0.1 1.6 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.4 001139410.1_53724001_2 - 0.061 13.0 14.2 3.9 7.2 0.1 4.1 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.10 001139410.1_53724001_2 - 0.17 10.8 10.8 2.2 7.1 10.8 2.2 1 1 0 1 1 1 0 L-fucokinase DIOX_N PF14226.4 001138710.1_53723001_1 - 1.6e-26 93.2 0.0 2.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.18 001138710.1_53723001_1 - 1.3e-10 41.5 0.0 2.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.18 001138710.1_53723001_3 - 2.2e-06 28.0 0.0 3.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_3 PF01596.15 001138711.1_53723001_1 - 2.9e-34 118.0 0.0 3.9e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001138711.1_53723001_1 - 0.034 15.1 0.0 0.051 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.15 001138711.1_53723001_3 - 4.6e-34 117.3 0.0 6.2e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase zf-CCCH PF00642.22 001139411.1_53724001_3 - 3.4e-45 151.0 49.5 1.5e-10 40.6 3.0 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.4 001139411.1_53724001_3 - 1.4e-08 34.8 50.4 0.014 15.7 4.8 5.4 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Torus PF16131.3 001139411.1_53724001_3 - 0.0011 19.6 26.3 0.81 10.3 0.4 5.2 3 1 2 5 5 5 4 Torus domain TLD PF07534.14 001138267.1_53723001_1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 TLD MPS2 PF17060.3 001138267.1_53723001_2 - 0.048 12.8 0.2 0.067 12.3 0.2 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Adaptin_N PF01602.18 001139190.1_53727001_2 - 2.3e-129 432.2 5.2 3e-129 431.8 5.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.8 001139190.1_53727001_2 - 2.2e-54 183.5 1.1 6.4e-54 182.0 1.1 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.3 001139190.1_53727001_2 - 1.3e-38 131.5 0.0 3e-38 130.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.4 001139190.1_53727001_2 - 1.1e-14 54.5 1.9 4.9e-05 23.5 0.0 5.6 3 2 2 5 5 5 4 HEAT repeats Cnd1 PF12717.5 001139190.1_53727001_2 - 3.6e-12 46.5 9.6 6.7e-06 26.1 0.5 4.6 2 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.5 001139190.1_53727001_2 - 0.005 16.0 0.9 9.5 5.2 0.5 3.7 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.4 001139190.1_53727001_2 - 0.0055 17.0 2.5 5.1 7.5 0.1 3.8 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.20 001139190.1_53727001_2 - 0.014 15.4 10.8 23 5.5 0.0 6.7 7 0 0 7 7 7 0 HEAT repeat CLASP_N PF12348.6 001139190.1_53727001_2 - 0.092 12.2 2.4 0.11 11.9 0.1 2.3 3 0 0 3 3 3 0 CLASP N terminal EF-hand_1 PF00036.30 001137822.1_53723001_3 - 1.3e-18 64.9 6.3 1.4e-05 24.2 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001137822.1_53723001_3 - 4.2e-14 51.2 6.8 4.6e-07 28.9 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001137822.1_53723001_3 - 1.3e-13 51.1 6.8 3e-08 33.9 0.8 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.4 001137822.1_53723001_3 - 5.7e-13 47.6 4.9 0.0062 16.3 0.3 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.4 001137822.1_53723001_3 - 3.4e-08 33.0 5.2 0.0002 20.9 0.6 3.4 2 2 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001137822.1_53723001_3 - 0.0047 17.1 0.3 0.021 15.0 0.3 2.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001137822.1_53723001_3 - 0.017 14.9 0.3 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PHB_acc_N PF07879.9 001137822.1_53723001_3 - 0.07 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain NUDIX PF00293.26 001138732.1_53723001_3 - 6.9e-12 45.4 0.1 1.1e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF1068 PF06364.10 001139196.1_53723001_3 - 6.9e-73 243.9 3.7 1e-72 243.4 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1068) Alpha_L_fucos PF01120.15 001138060.1_53725001_2 - 6.9e-34 117.7 0.0 1.3e-33 116.8 0.0 1.3 1 1 0 1 1 1 1 Alpha-L-fucosidase peroxidase PF00141.21 001139211.1_53723001_2 - 6.5e-46 156.7 0.0 9.5e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Kelch_1 PF01344.23 001138522.1_53724001_3 - 5.2e-19 67.4 10.3 4e-11 42.2 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.4 001138522.1_53724001_3 - 7.7e-14 51.3 7.8 7e-05 22.8 0.0 5.6 5 1 1 6 6 6 2 Kelch motif Kelch_4 PF13418.4 001138522.1_53724001_3 - 7.6e-09 35.3 0.9 0.0043 16.8 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.13 001138522.1_53724001_3 - 2.3e-06 27.2 3.9 0.066 13.1 0.1 5.4 5 1 0 5 5 5 2 Kelch motif F-box PF00646.31 001138522.1_53724001_3 - 3.5e-06 26.6 0.3 9.1e-06 25.3 0.3 1.7 1 0 0 1 1 1 1 F-box domain Kelch_3 PF13415.4 001138522.1_53724001_3 - 3.8e-05 23.7 3.9 0.9 9.8 0.0 5.0 4 1 0 4 4 4 2 Galactose oxidase, central domain F-box-like PF12937.5 001138522.1_53724001_3 - 0.048 13.4 0.1 0.22 11.3 0.1 2.2 2 0 0 2 2 2 0 F-box-like Kelch_5 PF13854.4 001138522.1_53724001_3 - 0.052 13.4 2.4 0.86 9.5 0.1 2.6 2 0 0 2 2 2 0 Kelch motif TAL_FSA PF00923.17 001138078.1_53723001_2 - 1.2e-48 165.8 0.0 1.5e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Rhomboid PF01694.20 001138084.1_53724001_2 - 6.5e-25 87.7 19.2 8.8e-25 87.3 17.6 1.9 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.13 001138084.1_53724001_2 - 7.1e-08 32.3 12.7 1.1e-07 31.6 12.7 1.3 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.8 001138084.1_53724001_2 - 4.7 7.7 10.4 0.049 14.1 2.1 2.1 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) UBA PF00627.29 001138084.1_53724001_3 - 3.3e-07 30.0 0.0 5.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain RRM_1 PF00076.20 001137857.1_53723001_1 - 3.8e-06 26.5 0.0 2.6e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001137857.1_53723001_1 - 0.0033 17.1 0.0 0.027 14.2 0.0 2.1 1 1 0 1 1 1 1 Occluded RNA-recognition motif eIF3_subunit PF08597.8 001137857.1_53723001_1 - 0.2 11.4 5.8 0.17 11.6 1.1 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CBM49 PF09478.8 001138768.1_53724001_3 - 0.032 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 GIDE PF12483.6 001138321.1_53724001_1 - 1.1e-27 96.4 0.0 2.4e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.4 001138321.1_53724001_1 - 1.2e-13 50.5 16.1 3.1e-13 49.2 16.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001138321.1_53724001_1 - 1.2e-07 31.3 14.7 2.4e-07 30.4 14.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.4 001138321.1_53724001_1 - 0.068 13.3 17.5 0.15 12.3 17.5 1.6 1 0 0 1 1 1 0 Ring finger domain AUX_IAA PF02309.14 001138108.1_53723001_2 - 3.8e-62 210.2 0.5 1.1e-60 205.3 0.5 2.7 1 1 0 1 1 1 1 AUX/IAA family Atrophin-1 PF03154.13 001138108.1_53723001_2 - 0.00054 18.3 4.3 0.00054 18.3 4.3 2.6 2 1 0 2 2 2 1 Atrophin-1 family DUF3915 PF13054.4 001138108.1_53723001_2 - 0.012 15.4 5.7 0.023 14.5 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PB1 PF00564.22 001138108.1_53723001_2 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 PB1 domain FAM27 PF15832.3 001138108.1_53723001_2 - 2.4 8.6 6.2 2.5 8.6 4.0 2.2 2 0 0 2 2 2 0 FAM27 D and E protein family BES1_N PF05687.11 001138108.1_53723001_2 - 3.3 8.0 7.1 10 6.4 7.1 1.8 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal zf-C3HC4_3 PF13920.4 001138109.1_53723001_1 - 5.1e-06 26.1 13.8 5.1e-06 26.1 13.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001138109.1_53723001_1 - 0.034 13.9 13.6 0.093 12.5 13.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_L12 PF00542.17 001139252.1_53724001_2 - 1.3e-20 73.4 4.4 2e-20 72.8 4.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.3 001139252.1_53724001_2 - 4.9 6.8 23.1 56 3.5 19.1 3.1 2 1 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain UQ_con PF00179.24 001137889.1_53722001_3 - 5.3e-53 178.3 0.0 6.8e-53 178.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001137889.1_53722001_3 - 0.00099 19.2 0.1 0.0023 18.1 0.1 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.4 001137889.1_53722001_3 - 0.0024 17.5 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.11 001137889.1_53722001_3 - 0.04 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain zf-CCCH PF00642.22 001138354.1_53724001_1 - 1.3e-21 75.8 27.8 1.2e-10 40.9 2.9 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.3 001138354.1_53724001_1 - 0.001 19.6 11.0 0.63 10.6 0.4 3.3 3 0 0 3 3 3 3 Torus domain oligo_HPY PF08352.10 001138354.1_53724001_1 - 0.4 11.1 6.7 13 6.3 0.0 3.6 3 0 0 3 3 3 0 Oligopeptide/dipeptide transporter, C-terminal region Lustrin_cystein PF14625.4 001138354.1_53724001_1 - 0.89 9.9 9.9 3.1 8.2 0.2 3.2 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain zf-CCCH_2 PF14608.4 001138354.1_53724001_1 - 1.6 9.2 25.7 0.11 12.9 2.7 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-RING_2 PF13639.4 001138361.1_53723001_3 - 1e-12 48.0 5.7 1e-12 48.0 5.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.3 001138361.1_53723001_3 - 4.7e-09 35.7 2.0 4.7e-09 35.7 2.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001138361.1_53723001_3 - 1.3e-08 34.4 5.8 2.8e-08 33.3 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001138361.1_53723001_3 - 1.2e-07 31.3 3.6 2.3e-07 30.5 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001138361.1_53723001_3 - 2.1e-07 31.0 7.1 6.2e-07 29.5 7.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.4 001138361.1_53723001_3 - 9.1e-06 25.5 1.2 9.1e-06 25.5 1.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001138361.1_53723001_3 - 1.4e-05 24.8 4.2 2.8e-05 23.9 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001138361.1_53723001_3 - 6.9e-05 22.5 2.5 6.9e-05 22.5 2.5 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.9 001138361.1_53723001_3 - 0.00094 19.3 3.0 0.0021 18.2 3.0 1.6 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.5 001138361.1_53723001_3 - 0.0019 18.1 2.3 0.0038 17.1 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.4 001138361.1_53723001_3 - 0.019 14.7 5.8 0.019 14.7 5.8 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.3 001138361.1_53723001_3 - 0.093 12.2 6.8 0.12 11.9 4.1 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.4 001138361.1_53723001_3 - 0.31 10.7 2.4 0.61 9.7 2.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.6 001138361.1_53723001_3 - 0.75 9.9 6.6 14 5.8 6.6 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.27 001138361.1_53723001_3 - 0.9 9.3 4.7 1.9 8.3 4.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-Di19 PF05605.10 001138361.1_53723001_3 - 1 9.6 4.0 33 4.7 4.0 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding RPS31 PF17067.3 001139051.1_53723001_1 - 0.63 10.1 5.6 0.52 10.4 1.5 2.3 2 0 0 2 2 2 0 Ribosomal protein S31e PPR_2 PF13041.4 001139051.1_53723001_2 - 8.8e-09 35.3 0.1 0.0046 17.0 0.1 3.3 1 1 2 3 3 3 3 PPR repeat family PPR PF01535.18 001139051.1_53723001_2 - 1.6e-06 27.8 0.2 0.0069 16.4 0.0 3.8 3 1 0 3 3 3 2 PPR repeat PPR_1 PF12854.5 001139051.1_53723001_2 - 0.0018 17.8 0.1 0.091 12.4 0.0 3.0 2 1 1 3 3 3 1 PPR repeat Sugar_tr PF00083.22 001138590.1_53724001_1 - 1.3e-101 340.6 20.3 1.8e-101 340.1 20.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001138590.1_53724001_1 - 3.1e-29 101.9 54.3 2.7e-27 95.5 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.11 001138590.1_53724001_1 - 0.00019 19.9 2.6 0.00019 19.9 2.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_9 PF00759.17 001138145.2_53724001_3 - 1.7e-134 449.2 0.0 1.7e-134 449.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 TPR_1 PF00515.26 001139291.1_53723001_1 - 2.9e-06 26.7 0.3 4.4e-05 23.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.4 001139291.1_53723001_1 - 4.2e-05 23.3 0.5 0.0049 16.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.15 001139291.1_53723001_1 - 0.0001 22.0 0.3 0.013 15.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2385 PF09539.8 001139291.1_53723001_1 - 0.0057 17.0 0.1 0.043 14.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2385) TPR_14 PF13428.4 001139291.1_53723001_1 - 0.0057 17.2 4.3 5.2 8.0 0.1 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.4 001139291.1_53723001_1 - 0.0083 16.5 7.1 0.11 12.8 3.4 3.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.4 001139291.1_53723001_1 - 0.031 14.4 3.1 11 6.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4372 PF14294.4 001139291.1_53723001_1 - 0.036 14.1 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) TPR_7 PF13176.4 001139291.1_53723001_1 - 0.05 13.5 5.4 1.4 9.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.4 001139291.1_53723001_1 - 0.8 9.5 5.9 1 9.2 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DNA_methylase PF00145.15 001137699.1_53725001_3 - 9.4e-15 54.6 0.0 1.1e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase UBA PF00627.29 001137699.1_53725001_3 - 6e-06 25.9 0.0 0.22 11.3 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain UQ_con PF00179.24 001137934.1_53723001_1 - 1.6e-43 147.6 0.0 2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.11 001137934.1_53723001_1 - 0.048 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.20 001137934.1_53723001_1 - 0.097 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain DEAD PF00270.27 001138616.1_53725001_3 - 8.2e-32 110.2 0.1 2e-31 109.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001138616.1_53725001_3 - 1.4e-25 89.6 0.2 4.1e-25 88.2 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.4 001138616.1_53725001_3 - 0.25 11.5 1.0 0.83 9.8 0.4 2.2 2 1 0 2 2 2 0 AAA domain DUF3138 PF11336.6 001138616.1_53725001_3 - 2.1 6.7 6.2 3.1 6.2 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1218 PF06749.10 001139314.1_53723001_2 - 3e-17 62.8 9.5 3e-17 62.8 9.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1218) HLH PF00010.24 001138851.1_53724001_2 - 2.2e-06 27.4 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Telomere_Sde2 PF13019.4 001139318.1_53724001_1 - 1.6e-45 154.8 0.7 2.6e-45 154.0 0.7 1.4 1 0 0 1 1 1 1 Telomere stability and silencing Telomere_Sde2_2 PF13297.4 001139318.1_53724001_1 - 2.9e-26 90.8 3.3 5.2e-26 89.9 3.3 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal Pox_Ag35 PF03286.12 001139318.1_53724001_1 - 4 7.0 13.7 0.46 10.1 4.5 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein UQ_con PF00179.24 001139323.1_53724001_3 - 7.9e-24 83.8 0.0 1.2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Flavoprotein PF02441.17 001139334.1_53723001_1 - 9.3e-45 152.1 0.0 1.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein Zip PF02535.20 001137726.1_53724001_2 - 1.3e-55 188.8 16.6 1.3e-55 188.8 16.6 2.6 1 1 1 2 2 2 1 ZIP Zinc transporter TMEM132D_C PF15706.3 001137726.1_53724001_2 - 0.13 11.9 0.5 1.9 8.2 0.0 2.8 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Dynein_light PF01221.16 001139339.1_53722001_2 - 7.8e-37 125.3 1.9 1e-36 124.9 1.9 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Suc_Fer-like PF06999.10 001138876.1_53724001_2 - 5e-43 147.1 0.0 6.4e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2036 PF09724.7 001143021.1_53723001_2 - 2.2e-86 290.0 0.0 2.6e-86 289.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) cobW PF02492.17 001143255.1_53723001_3 - 5.4e-53 179.1 0.7 8.3e-53 178.4 0.7 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.12 001143255.1_53723001_3 - 2.6e-16 59.2 0.0 4.8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DUF258 PF03193.14 001143255.1_53723001_3 - 2e-05 24.4 0.2 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001143255.1_53723001_3 - 0.001 19.0 2.4 0.0094 15.9 1.0 3.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.4 001143255.1_53723001_3 - 0.0033 17.7 0.1 0.01 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.25 001143255.1_53723001_3 - 0.0034 16.8 0.6 0.19 11.1 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.4 001143255.1_53723001_3 - 0.005 16.4 0.3 0.015 14.9 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.25 001143255.1_53723001_3 - 0.012 16.0 0.1 0.042 14.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.4 001143255.1_53723001_3 - 0.017 15.2 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.4 001143255.1_53723001_3 - 0.021 15.2 0.4 0.052 13.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.14 001143255.1_53723001_3 - 0.029 13.2 0.4 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 ArgK protein HSBP1 PF06825.10 001143255.1_53723001_3 - 0.035 13.9 0.4 0.11 12.3 0.4 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 ATP_bind_1 PF03029.15 001143255.1_53723001_3 - 0.039 13.6 0.6 2.5 7.7 0.3 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.16 001143255.1_53723001_3 - 0.058 13.2 0.3 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.10 001143255.1_53723001_3 - 0.075 12.2 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Pollen_allerg_1 PF01357.19 001143267.1_53723001_3 - 2e-08 34.0 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen Pkinase PF00069.23 001143527.1_53724001_1 - 1.3e-65 221.3 0.0 1.6e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001143527.1_53724001_1 - 5.6e-34 117.5 0.0 7.2e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001143527.1_53724001_1 - 7.1e-08 32.0 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001143527.1_53724001_1 - 0.00044 20.1 0.1 0.24 11.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.12 001143527.1_53724001_1 - 0.0022 17.3 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001143527.1_53724001_1 - 0.0046 16.5 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.9 001143527.1_53724001_1 - 0.19 10.6 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Transp_cyt_pur PF02133.13 001143063.1_53724001_3 - 9.5e-96 321.1 28.2 1.1e-95 320.9 28.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AP2 PF00847.18 001143592.1_53724001_2 - 1.1e-26 92.8 9.6 3.9e-13 49.3 1.1 2.4 2 0 0 2 2 2 2 AP2 domain TB2_DP1_HVA22 PF03134.17 001143595.1_53724001_1 - 2.2e-22 78.6 8.6 2.2e-22 78.6 8.6 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family TFIIA PF03153.11 001143595.1_53724001_1 - 0.42 10.4 13.4 0.55 10.0 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.13 001143595.1_53724001_1 - 0.93 8.9 5.3 1.4 8.3 5.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.6 001143595.1_53724001_1 - 2.7 7.4 16.4 4.1 6.8 16.4 1.2 1 0 0 1 1 1 0 Spt20 family TAXi_N PF14543.4 001143140.1_53723001_1 - 2.8e-43 148.1 4.5 5.1e-43 147.2 4.5 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.4 001143140.1_53723001_1 - 2e-27 95.8 0.0 3.9e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.21 001143140.1_53723001_1 - 1.1e-18 67.6 1.2 3e-14 53.0 1.2 3.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Myb_DNA-bind_3 PF12776.5 001143384.1_53723001_2 - 0.00012 22.7 0.0 0.00024 21.7 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF1635 PF07795.9 001143389.1_53723001_1 - 0.0031 17.4 4.3 0.0056 16.5 4.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) Gp-FAR-1 PF05823.10 001143389.1_53723001_1 - 0.038 14.2 1.9 0.058 13.6 1.9 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) RTBV_P46 PF06216.9 001143389.1_53723001_1 - 0.24 10.1 1.6 0.37 9.5 1.6 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF641 PF04859.10 001143389.1_53723001_1 - 0.78 9.9 6.9 1.5 9.1 6.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) OmpH PF03938.12 001143389.1_53723001_1 - 0.93 9.3 7.8 1.5 8.7 7.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) adh_short PF00106.23 001143393.1_53723001_1 - 3.3e-35 121.2 0.3 1.8e-26 92.6 0.2 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.4 001143393.1_53723001_1 - 1.8e-24 86.4 0.1 4.9e-10 39.2 0.1 3.1 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001143393.1_53723001_1 - 5.4e-07 29.6 0.2 9.1e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001143393.1_53723001_1 - 0.022 14.1 0.1 0.05 12.9 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Dynein_light PF01221.16 001143168.1_53722001_1 - 3.1e-29 101.0 0.1 4.6e-29 100.4 0.1 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Herpes_TK_C PF08465.8 001143634.1_53724001_2 - 0.06 12.9 4.8 2.5 7.8 0.6 2.4 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal Thyroglobulin_1 PF00086.16 001143634.1_53724001_2 - 0.1 12.1 1.4 0.21 11.2 1.4 1.4 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat UDPGT PF00201.16 001143415.1_53724001_1 - 5.6e-19 68.2 0.2 8.2e-19 67.6 0.2 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PP2 PF14299.4 001143658.1_53723001_2 - 1.5e-47 161.1 0.0 2.1e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Phloem protein 2 PUNUT PF16913.3 001157567.1_53723001_1 - 8.1e-88 294.6 10.4 9.4e-88 294.4 10.4 1.0 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.9 001157567.1_53723001_1 - 3e-05 23.2 2.7 4.2e-05 22.8 2.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.18 001157567.1_53723001_1 - 8.5e-05 22.6 15.7 8.5e-05 22.6 15.7 2.9 2 2 1 3 3 3 1 EamA-like transporter family CRT-like PF08627.8 001157567.1_53723001_1 - 0.008 15.0 3.5 0.04 12.7 0.1 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.14 001157567.1_53723001_1 - 0.1 11.8 6.2 0.65 9.2 6.2 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family NDK PF00334.17 001156551.1_53723001_2 - 1.7e-51 173.6 0.0 2.4e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.16 001156551.1_53723001_2 - 0.077 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ PaREP1 PF05942.9 001156551.1_53723001_2 - 0.38 10.5 3.0 5 6.9 0.1 2.3 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family PPR PF01535.18 001148553.1_53724001_1 - 8.3e-67 216.8 19.4 9.3e-10 38.0 0.0 13.8 14 0 0 14 14 14 9 PPR repeat PPR_2 PF13041.4 001148553.1_53724001_1 - 7.6e-66 218.0 6.5 3.6e-12 46.1 0.0 10.9 6 4 5 11 11 11 8 PPR repeat family PPR_1 PF12854.5 001148553.1_53724001_1 - 5.1e-39 131.5 9.6 4.5e-07 29.3 0.0 10.3 10 2 2 12 12 12 7 PPR repeat PPR_3 PF13812.4 001148553.1_53724001_1 - 3.7e-16 58.8 0.0 0.14 12.1 0.0 8.0 5 3 3 8 8 8 4 Pentatricopeptide repeat domain TPR_14 PF13428.4 001148553.1_53724001_1 - 5.9e-07 29.6 0.2 0.1 13.4 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR_long PF17177.2 001148553.1_53724001_1 - 1.1e-05 24.8 0.0 0.094 11.9 0.0 4.1 3 2 1 4 4 4 1 Pentacotripeptide-repeat region of PROPR TPR_7 PF13176.4 001148553.1_53724001_1 - 3.3e-05 23.5 0.3 0.59 10.2 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.26 001148553.1_53724001_1 - 0.0039 16.8 0.0 0.088 12.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.7 001148553.1_53724001_1 - 0.0052 16.3 0.0 3.9 7.0 0.0 3.9 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_2 PF07719.15 001148553.1_53724001_1 - 0.0097 15.8 0.4 2.8 8.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.4 001148553.1_53724001_1 - 0.026 14.7 0.1 0.85 9.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.4 001148553.1_53724001_1 - 0.027 14.0 0.1 1.1 8.9 0.3 2.7 2 0 0 2 2 2 0 TPR repeat BTAD PF03704.15 001148553.1_53724001_1 - 0.062 13.6 0.1 4.9 7.4 0.0 3.3 4 0 0 4 4 4 0 Bacterial transcriptional activator domain ANAPC3 PF12895.5 001148553.1_53724001_1 - 0.069 13.2 0.0 0.61 10.2 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Vps39_1 PF10366.7 001148553.1_53724001_1 - 0.1 12.8 0.0 8.2 6.6 0.0 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 TPR_19 PF14559.4 001148553.1_53724001_1 - 0.12 12.7 0.1 3.9 7.9 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat PIG-X PF08320.10 001149526.1_53723001_3 - 2.4e-17 63.4 0.0 3.5e-16 59.6 0.0 2.1 1 1 0 1 1 1 1 PIG-X / PBN1 SEP PF08059.11 001155283.1_53723001_3 - 2e-23 82.6 0.0 5e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.18 001155283.1_53723001_3 - 4.2e-16 58.8 0.0 6.4e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain EFP_N PF08207.10 001158844.1_53722001_2 - 3.3e-25 87.7 0.1 6.9e-25 86.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.9 001158844.1_53722001_2 - 9.1e-22 76.4 0.2 2.1e-21 75.3 0.2 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.18 001158844.1_53722001_2 - 1.8e-20 72.5 0.2 2.8e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain RRM_1 PF00076.20 001154266.1_53723001_3 - 2.2e-34 117.0 0.0 2.2e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001154266.1_53723001_3 - 1.7e-07 30.8 0.0 4.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.6 001154266.1_53723001_3 - 0.0024 17.8 0.2 1.1 9.3 0.1 2.9 2 2 0 2 2 2 2 Limkain b1 PHM7_cyt PF14703.4 001154266.1_53723001_3 - 0.019 15.1 0.1 5.1 7.2 0.0 2.7 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.3 001154266.1_53723001_3 - 0.047 13.4 0.0 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif PCDO_beta_N PF12391.6 001153009.1_53726001_3 - 0.026 14.0 0.2 0.026 14.0 0.2 2.0 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Glyco_hydro_9 PF00759.17 001148556.1_53724001_1 - 1.1e-138 463.0 1.7 1.3e-138 462.7 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 zf-U1 PF06220.10 001158339.1_53723001_1 - 2.1e-09 36.8 0.2 3.9e-09 36.0 0.2 1.5 1 0 0 1 1 1 1 U1 zinc finger Spore_II_R PF09551.8 001158339.1_53723001_1 - 0.17 12.2 2.3 0.33 11.3 2.3 1.4 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF1033 PF06279.9 001158339.1_53723001_1 - 0.32 11.0 3.0 0.17 11.9 0.5 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) DUF616 PF04765.11 001147853.1_53724001_3 - 1.8e-126 421.5 0.0 2.2e-126 421.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF616) XG_FTase PF03254.11 001148800.1_53725001_1 - 1.6e-190 633.6 0.0 2.1e-190 633.3 0.0 1.0 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase B56 PF01603.18 001154529.1_53725001_2 - 9.4e-182 604.4 0.0 1.3e-181 604.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Trp_syntA PF00290.18 001147609.1_53723001_2 - 1.2e-92 309.3 0.0 1.5e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.19 001147609.1_53723001_2 - 9.1e-08 31.7 0.1 1.6e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.12 001147609.1_53723001_2 - 0.00012 21.4 0.1 0.00023 20.4 0.1 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG PcrB PF01884.15 001147609.1_53723001_2 - 0.00049 19.5 0.1 0.0029 17.0 0.1 2.0 2 0 0 2 2 2 1 PcrB family FMN_dh PF01070.16 001147609.1_53723001_2 - 0.0013 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.12 001147609.1_53723001_2 - 0.0029 16.7 0.1 0.0053 15.8 0.1 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.13 001147609.1_53723001_2 - 0.0046 16.2 0.1 0.0046 16.2 0.1 2.0 3 0 0 3 3 3 1 Nitronate monooxygenase IGPS PF00218.19 001147609.1_53723001_2 - 0.024 13.7 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Dus PF01207.15 001147609.1_53723001_2 - 0.027 13.5 0.1 0.055 12.4 0.1 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) TMP-TENI PF02581.15 001147609.1_53723001_2 - 0.077 12.2 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI NAM PF02365.13 001147110.1_53724001_3 - 9.6e-28 96.7 0.3 2.6e-27 95.4 0.3 1.8 1 0 0 1 1 1 1 No apical meristem (NAM) protein ILVD_EDD PF00920.19 001148088.1_53725001_1 - 7.5e-214 711.0 0.0 8.9e-214 710.7 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family ADH_zinc_N PF00107.24 001157069.1_53723001_1 - 2.2e-22 79.2 0.1 4.1e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.4 001157069.1_53723001_1 - 7.6e-16 59.2 0.3 2.1e-15 57.8 0.0 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001157069.1_53723001_1 - 4.8e-08 32.7 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.19 001157069.1_53723001_1 - 0.017 14.3 2.1 0.028 13.6 2.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4059 PF13268.4 001157069.1_53723001_2 - 0.014 15.7 0.6 0.03 14.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) GNT-I PF03071.13 001148806.1_53724001_1 - 1.2e-193 643.6 4.4 1.5e-193 643.3 4.4 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.4 001148806.1_53724001_1 - 8.3e-09 35.5 0.1 3.4e-08 33.5 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.24 001148806.1_53724001_1 - 0.0088 15.7 0.3 0.029 14.1 0.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 MGAT2 PF05060.12 001148806.1_53724001_1 - 0.0094 14.9 1.9 0.15 10.9 0.3 2.2 2 0 0 2 2 2 1 N-acetylglucosaminyltransferase II (MGAT2) Glyco_transf_25 PF01755.15 001148806.1_53724001_1 - 0.055 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) RNase_HII PF01351.16 001148806.1_53724001_1 - 0.14 11.9 1.9 0.24 11.0 1.9 1.3 1 0 0 1 1 1 0 Ribonuclease HII Gamma-thionin PF00304.18 001153510.1_53722001_1 - 1.9e-07 31.1 12.8 1.9e-07 31.1 12.8 1.6 2 0 0 2 2 2 1 Gamma-thionin family Med19 PF10278.7 001153510.1_53722001_3 - 2.1 8.1 21.2 3 7.6 21.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 OAD_gamma PF04277.11 001153510.1_53722001_3 - 4.4 7.8 6.2 6.4 7.3 6.2 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AP3D1 PF06375.9 001153510.1_53722001_3 - 6.4 6.9 17.5 8.7 6.5 17.5 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 SR-25 PF10500.7 001153510.1_53722001_3 - 8.2 5.8 21.3 10 5.5 21.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein adh_short_C2 PF13561.4 001147614.1_53723001_1 - 5.9e-67 225.5 4.9 8.8e-67 224.9 4.9 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001147614.1_53723001_1 - 3.5e-65 219.0 6.5 4.7e-65 218.6 6.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001147614.1_53723001_1 - 3.1e-20 72.7 2.1 5e-20 72.0 2.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001147614.1_53723001_1 - 0.07 12.4 0.3 0.16 11.3 0.3 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PLATZ PF04640.12 001152112.1_53722001_2 - 5.9e-28 97.2 1.2 5.9e-28 97.2 1.2 2.2 2 1 0 2 2 2 1 PLATZ transcription factor zf-B_box PF00643.22 001152112.1_53722001_2 - 0.00053 19.9 7.3 0.00053 19.9 7.3 2.5 2 0 0 2 2 2 1 B-box zinc finger DZR PF12773.5 001152112.1_53722001_2 - 0.67 9.9 15.4 1.1 9.2 6.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon Complex1_51K PF01512.15 001155295.1_53724001_3 - 1.6e-46 157.8 0.0 2.7e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.7 001155295.1_53724001_3 - 2.4e-29 101.1 0.0 5e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.7 001155295.1_53724001_3 - 2.1e-07 30.6 0.0 4.7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 SLBB domain CAP_N PF01213.17 001155295.1_53724001_3 - 0.11 11.8 2.1 0.25 10.7 2.1 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Dscam_C PF12355.6 001155295.1_53724001_3 - 0.17 12.7 0.9 0.34 11.8 0.9 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal F-box PF00646.31 001156565.1_53723001_3 - 1.8e-05 24.4 0.7 3.5e-05 23.4 0.7 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001156565.1_53723001_3 - 4.4e-05 23.1 0.7 9.4e-05 22.1 0.7 1.5 1 0 0 1 1 1 1 F-box-like Kelch_6 PF13964.4 001156565.1_53723001_3 - 0.0015 18.6 0.0 5.7 7.3 0.0 3.5 3 0 0 3 3 3 2 Kelch motif FGGY_C PF02782.14 001155549.1_53725001_3 - 2e-26 92.8 0.0 3.8e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.19 001155549.1_53725001_3 - 1.1e-24 87.3 0.0 5.6e-16 58.7 0.0 2.1 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain EHD_N PF16880.3 001147116.1_53725001_3 - 5.1e-15 54.9 0.5 9.3e-15 54.1 0.5 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.21 001147116.1_53725001_3 - 4.5e-12 46.2 0.0 2.6e-10 40.5 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.21 001147116.1_53725001_3 - 2.2e-08 34.1 0.0 4.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_4 PF12763.5 001147116.1_53725001_3 - 2.8e-06 27.1 0.0 8.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.30 001147116.1_53725001_3 - 3.4e-06 26.1 0.0 0.085 12.3 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.4 001147116.1_53725001_3 - 1.2e-05 25.5 0.0 4e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair GTP_EFTU PF00009.25 001147116.1_53725001_3 - 0.00023 20.6 0.0 0.00073 19.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.4 001147116.1_53725001_3 - 0.0056 16.4 0.0 2.9 8.0 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain Roc PF08477.11 001147116.1_53725001_3 - 0.0067 16.5 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_8 PF13833.4 001147116.1_53725001_3 - 0.04 13.5 0.8 4.5 7.0 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain pair AAA_28 PF13521.4 001147116.1_53725001_3 - 0.047 13.8 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.4 001147116.1_53725001_3 - 0.079 12.5 0.5 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain PAS_4 PF08448.8 001148810.1_53724001_1 - 0.039 14.1 2.3 0.083 13.0 2.3 1.4 1 0 0 1 1 1 0 PAS fold BET PF17035.3 001148810.1_53724001_2 - 8.4e-25 86.6 1.6 1.9e-24 85.5 1.6 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.23 001148810.1_53724001_2 - 5.7e-19 67.9 0.0 1.1e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain CorA PF01544.16 001148810.1_53724001_2 - 0.25 10.5 0.9 0.43 9.7 0.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IMUP PF15761.3 001148810.1_53724001_2 - 2.8 8.5 25.7 5.2 7.7 1.3 3.1 3 0 0 3 3 3 0 Immortalisation up-regulated protein AMP-binding PF00501.26 001158860.1_53726001_1 - 5.1e-42 143.8 0.0 7.6e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.3 001158860.1_53726001_1 - 2.2e-07 30.5 0.4 4.3e-07 29.6 0.4 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.4 001158860.1_53726001_1 - 5.8e-06 27.1 0.1 3.7e-05 24.5 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Myb_DNA-binding PF00249.29 001147118.1_53723001_3 - 2.2e-32 110.8 5.4 4.1e-16 58.7 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001147118.1_53723001_3 - 2.1e-15 56.5 1.1 2.3e-08 34.0 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001147118.1_53723001_3 - 0.052 13.4 0.0 0.54 10.2 0.0 2.5 3 0 0 3 3 3 0 SLIDE DUF3683 PF12447.6 001147118.1_53723001_3 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) SWIB PF02201.16 001157332.1_53722001_1 - 1.3e-26 92.2 0.0 1.7e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 SWIB/MDM2 domain L51_S25_CI-B8 PF05047.14 001155302.1_53722001_1 - 2.7e-13 49.5 0.2 4.7e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ENTH PF01417.18 001150890.1_53723001_2 - 1e-24 86.8 0.0 1.4e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.14 001150890.1_53723001_2 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Telomere_Sde2 PF13019.4 001150890.1_53723001_2 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Telomere stability and silencing Methyltransf_2 PF00891.16 001152787.1_53723001_3 - 3.7e-54 183.2 0.0 6.1e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.9 001152787.1_53723001_3 - 6.3e-10 38.8 0.0 1.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_25 PF13649.4 001152787.1_53723001_3 - 0.0011 19.5 0.1 0.0027 18.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001152787.1_53723001_3 - 0.015 15.8 0.1 0.077 13.6 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.10 001152787.1_53723001_3 - 0.017 15.6 0.1 0.046 14.2 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.27 001157592.1_53724001_1 - 1.8e-40 138.4 0.0 3.1e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001157592.1_53724001_1 - 3e-30 104.7 0.1 1.6e-28 99.2 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.13 001157592.1_53724001_1 - 5.1e-06 26.5 0.0 8.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.4 001157592.1_53724001_1 - 0.0042 16.3 0.2 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.4 001157592.1_53724001_1 - 0.026 14.8 0.0 0.065 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.4 001157592.1_53724001_1 - 0.037 14.2 0.1 0.14 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain Kri1 PF05178.10 001157592.1_53724001_1 - 0.066 13.6 0.3 0.19 12.1 0.2 1.8 2 0 0 2 2 2 0 KRI1-like family FUSC-like PF12805.5 001157592.1_53724001_1 - 0.14 11.1 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS GPCR_chapero_1 PF11904.6 001153272.1_53726001_3 - 1.7e-99 333.0 0.0 2.6e-99 332.4 0.0 1.3 1 0 0 1 1 1 1 GPCR-chaperone Ank_5 PF13857.4 001153272.1_53726001_3 - 0.00011 22.4 0.0 0.00011 22.4 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.5 001153272.1_53726001_3 - 0.0012 19.3 0.2 0.0029 18.0 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001153272.1_53726001_3 - 0.025 15.0 0.0 0.07 13.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.4 001153272.1_53726001_3 - 0.087 13.3 1.0 1 10.0 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat SnoaL_2 PF12680.5 001149366.1_53722001_2 - 0.034 14.7 0.0 0.06 13.9 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain DUF2358 PF10184.7 001149366.1_53722001_2 - 0.045 13.9 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) SnoaL PF07366.10 001149366.1_53722001_2 - 0.08 12.6 0.0 0.26 10.9 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Formyl_trans_C PF02911.16 001149366.1_53722001_2 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain LTV PF04180.12 001149547.1_53724001_1 - 0.61 9.6 6.0 4.8 6.7 5.5 2.0 1 1 0 1 1 1 0 Low temperature viability protein HLH PF00010.24 001147377.1_53723001_2 - 4.9e-14 51.9 0.3 4.9e-14 51.9 0.3 2.5 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF1207 PF06727.9 001147377.1_53723001_2 - 0.19 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) Cyclin_N PF00134.21 001155561.1_53724001_1 - 1.5e-46 157.2 1.8 1.5e-46 157.2 1.8 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001155561.1_53724001_1 - 1.4e-33 115.3 1.7 1.4e-33 115.3 1.7 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Myb_DNA-binding PF00249.29 001152123.1_53724001_2 - 3e-14 52.8 0.9 6.8e-14 51.6 0.9 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001152123.1_53724001_2 - 0.00013 22.0 0.5 0.00027 21.0 0.5 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001152123.1_53724001_2 - 0.00094 18.9 0.2 0.0021 17.8 0.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like C2 PF00168.28 001155054.1_53722001_1 - 1.2e-21 76.8 0.0 1.7e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 C2 domain DOCK-C2 PF14429.4 001155054.1_53722001_1 - 0.039 13.7 0.0 0.093 12.4 0.0 1.6 1 1 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Pyrophosphatase PF00719.17 001147379.1_53723001_1 - 1.1e-46 158.5 0.2 1.3e-46 158.2 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Aconitase PF00330.18 001148107.1_53724001_1 - 1.4e-20 73.6 0.0 1.7e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.17 001148107.1_53724001_1 - 6e-11 42.7 0.0 9.1e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.18 001148107.1_53724001_2 - 1.1e-17 64.0 0.1 1.5e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) RCC1 PF00415.16 001148107.1_53724001_3 - 0.0026 18.2 0.0 0.017 15.6 0.0 2.2 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat SPC12 PF06645.11 001158871.1_53723001_2 - 2.5e-29 101.0 0.4 4.7e-29 100.1 0.4 1.5 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Acyl-CoA_dh_1 PF00441.22 001156834.1_53724001_1 - 9.1e-25 87.5 0.0 1.3e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.14 001156834.1_53724001_1 - 3.3e-23 82.4 0.0 6.7e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.17 001156834.1_53724001_1 - 6.4e-22 77.4 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.9 001156834.1_53724001_1 - 0.0093 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SurE PF01975.15 001157599.1_53724001_1 - 5.2e-40 136.9 0.1 5.2e-40 136.9 0.1 1.6 2 0 0 2 2 2 1 Survival protein SurE PARM PF17061.3 001157599.1_53724001_1 - 5.1 7.0 9.3 0.41 10.6 4.0 1.8 2 0 0 2 2 2 0 PARM Pollen_allerg_1 PF01357.19 001156582.1_53723001_1 - 1.2e-25 89.2 0.0 2.6e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001156582.1_53723001_1 - 6.7e-16 58.2 0.1 6.7e-16 58.2 0.1 1.7 2 0 0 2 2 2 1 Lytic transglycolase SSB PF00436.23 001158367.1_53723001_2 - 1.6e-16 60.1 0.1 3.4e-16 59.1 0.0 1.5 2 0 0 2 2 2 1 Single-strand binding protein family MtN3_slv PF03083.14 001146896.1_53723001_3 - 2.2e-40 136.4 11.4 1.6e-20 72.8 5.1 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF962 PF06127.9 001146896.1_53723001_3 - 0.12 12.3 1.0 0.36 10.8 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) TP6A_N PF04406.12 001148111.1_53724001_1 - 1.7e-21 75.8 0.0 3.6e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase LCE6A PF15858.3 001148111.1_53724001_1 - 0.76 10.4 2.3 1.9 9.2 2.3 1.6 1 0 0 1 1 1 0 Late cornified envelope protein 6A family LTP_2 PF14368.4 001158113.1_53722001_1 - 1e-17 63.9 2.5 2e-17 63.0 2.5 1.5 1 0 0 1 1 1 1 Probable lipid transfer Tryp_alpha_amyl PF00234.20 001158113.1_53722001_1 - 8.5e-07 29.2 1.1 1.9e-06 28.1 1.1 1.5 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family Pkinase PF00069.23 001146897.1_53723001_3 - 1e-34 120.0 0.0 1.4e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001146897.1_53723001_3 - 3.2e-34 118.2 0.0 7.9e-34 117.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001146897.1_53723001_3 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FBPase PF00316.18 001148112.1_53724001_3 - 6.2e-79 263.8 0.0 8.4e-79 263.4 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Lung_7-TM_R PF06814.11 001158876.1_53724001_1 - 4.1e-42 144.2 7.2 6.4e-42 143.6 7.2 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor RNA_pol_L_2 PF13656.4 001148585.1_53724001_1 - 8.7e-23 79.8 0.1 1.3e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.22 001148585.1_53724001_1 - 5.6e-07 28.8 0.0 9.1e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_S2 PF00318.18 001156332.1_53723001_1 - 4.6e-25 88.0 0.0 5.8e-12 45.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.3 001156332.1_53723001_1 - 7.6e-06 27.1 9.5 1.3e-05 26.3 9.5 1.3 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus V-SNARE_C PF12352.6 001157607.1_53723001_3 - 7.8e-17 61.2 1.7 7.8e-17 61.2 1.7 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Not3 PF04065.13 001157607.1_53723001_3 - 0.0023 17.3 0.3 0.0029 17.0 0.3 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Tektin PF03148.12 001157607.1_53723001_3 - 0.0056 15.3 3.7 0.015 14.0 3.7 1.6 1 1 0 1 1 1 1 Tektin family COG5 PF10392.7 001157607.1_53723001_3 - 0.027 14.5 2.5 0.055 13.5 1.2 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Sec20 PF03908.11 001157607.1_53723001_3 - 0.11 12.3 7.0 0.12 12.1 0.1 2.7 2 1 1 3 3 3 0 Sec20 Ribosomal_L28 PF00830.17 001154560.1_53722001_3 - 7e-20 70.9 4.5 9.9e-20 70.4 4.5 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Alb1 PF09135.9 001154560.1_53722001_3 - 0.054 14.3 1.6 0.092 13.6 1.6 1.3 1 0 0 1 1 1 0 Alb1 DUF1118 PF06549.10 001154560.1_53722001_3 - 0.15 12.2 1.9 15 5.8 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1118) Pkinase PF00069.23 001148833.1_53724001_2 - 5.9e-43 147.0 0.0 1.6e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.15 001148833.1_53724001_2 - 2.7e-17 62.8 0.0 2.4e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.21 001148833.1_53724001_2 - 0.0086 15.9 0.1 1.3 8.8 0.0 3.0 2 1 0 3 3 3 1 Phosphotransferase enzyme family VWA_2 PF13519.4 001147392.1_53723001_3 - 6.2e-27 94.3 0.0 1.9e-26 92.7 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.18 001147392.1_53723001_3 - 6.8e-08 31.8 21.4 0.0017 18.0 2.2 4.4 4 0 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.12 001147392.1_53723001_3 - 0.005 16.5 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like Cofilin_ADF PF00241.18 001153046.1_53724001_3 - 3.5e-22 78.8 0.0 1.7e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein GATA PF00320.25 001147641.1_53724001_2 - 5e-27 93.1 10.7 1.5e-14 53.2 3.6 2.5 2 0 0 2 2 2 2 GATA zinc finger DZR PF12773.5 001147641.1_53724001_2 - 0.00021 21.1 4.7 0.23 11.4 0.3 3.1 2 1 0 2 2 2 2 Double zinc ribbon OrfB_Zn_ribbon PF07282.9 001147641.1_53724001_2 - 1.2 9.0 5.6 5 7.0 1.1 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PknG_rubred PF16919.3 001147641.1_53724001_2 - 1.5 8.8 9.8 2.7 8.0 1.8 2.4 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain AAA PF00004.27 001156338.1_53724001_3 - 8.6e-39 132.9 0.0 2.4e-38 131.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.8 001156338.1_53724001_3 - 8.1e-11 41.6 0.1 2.7e-10 39.9 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.10 001156338.1_53724001_3 - 5e-05 22.5 0.0 8.2e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.12 001156338.1_53724001_3 - 0.00098 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.4 001156338.1_53724001_3 - 0.001 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.12 001156338.1_53724001_3 - 0.0017 18.2 0.1 0.019 14.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.4 001156338.1_53724001_3 - 0.0052 16.9 0.1 0.26 11.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.15 001156338.1_53724001_3 - 0.007 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.19 001156338.1_53724001_3 - 0.0076 15.5 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.11 001156338.1_53724001_3 - 0.0082 15.0 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus TsaE PF02367.15 001156338.1_53724001_3 - 0.016 15.0 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.4 001156338.1_53724001_3 - 0.024 14.9 0.1 0.073 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.14 001156338.1_53724001_3 - 0.038 13.3 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.4 001156338.1_53724001_3 - 0.058 13.8 0.7 0.33 11.3 0.7 2.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001156338.1_53724001_3 - 0.079 13.2 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.4 001156338.1_53724001_3 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Apt1 PF10351.7 001156338.1_53724001_3 - 3.4 6.3 6.2 5 5.7 6.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lysine_decarbox PF03641.12 001157356.1_53723001_2 - 1.5e-25 89.7 0.0 2.2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Aldo_ket_red PF00248.19 001156595.1_53723001_1 - 2e-46 158.4 0.0 7e-46 156.6 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Jagunal PF07086.10 001150101.1_53722001_1 - 9.5e-07 29.0 1.4 3e-06 27.4 0.0 2.0 1 1 1 2 2 2 1 Jagunal, ER re-organisation during oogenesis Pkinase_Tyr PF07714.15 001157614.1_53725001_1 - 2.8e-66 223.3 0.0 3.8e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001157614.1_53725001_1 - 1.1e-54 185.5 0.0 1.6e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.4 001157614.1_53725001_1 - 0.064 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.21 001157614.1_53725001_1 - 0.097 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Xan_ur_permease PF00860.18 001147396.2_53725001_2 - 1.6e-67 227.8 27.6 1.9e-67 227.5 27.6 1.1 1 0 0 1 1 1 1 Permease family HR_lesion PF05514.9 001155327.1_53722001_2 - 4.6e-59 198.4 5.5 5.8e-59 198.1 5.5 1.1 1 0 0 1 1 1 1 HR-like lesion-inducing bZIP_1 PF00170.19 001158889.1_53724001_3 - 0.00014 21.8 11.1 0.00048 20.0 4.7 2.5 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.13 001158889.1_53724001_3 - 0.018 15.0 2.1 0.018 15.0 2.1 2.8 3 0 0 3 3 3 0 Basic region leucine zipper DUF972 PF06156.11 001158889.1_53724001_3 - 0.024 15.1 4.3 0.049 14.1 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.15 001158889.1_53724001_3 - 1.8 9.0 11.5 0.049 14.0 2.2 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor MotB_plug PF13677.4 001151635.1_53722001_1 - 0.26 10.8 1.0 0.48 9.9 1.0 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB PP2C PF00481.19 001154312.1_53725001_1 - 1.8e-40 139.1 0.0 5e-39 134.4 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C CLU_N PF15044.4 001147146.1_53723001_2 - 8.5e-10 38.8 0.1 1.3e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term Rhodanese PF00581.18 001153803.1_53723001_3 - 9.8e-08 32.4 0.0 3.3e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain NTF2 PF02136.18 001157619.1_53725001_1 - 5.4e-25 88.1 0.4 1.3e-24 87.0 0.4 1.7 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.20 001157619.1_53725001_1 - 1.1e-10 41.1 0.2 2.1e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.17 001153807.1_53723001_1 - 8.7e-50 169.0 0.0 2.2e-48 164.5 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.12 001153807.1_53723001_1 - 1.9e-08 34.0 0.0 1.4e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.15 001153807.1_53723001_1 - 0.0011 18.6 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.22 001153807.1_53723001_1 - 0.0012 18.6 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.26 001153807.1_53723001_1 - 0.0023 17.6 0.1 0.36 10.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Pyr_redox_2 PF07992.12 001152818.1_53725001_1 - 5.1e-52 176.8 0.0 6.7e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001152818.1_53725001_1 - 8.3e-08 32.6 0.1 7.2e-06 26.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.20 001158899.1_53723001_2 - 4.8e-60 201.7 0.1 6.2e-60 201.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001158899.1_53723001_2 - 1.7e-33 115.3 0.1 2.6e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001158899.1_53723001_2 - 5.3e-13 48.7 0.0 7.5e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001158899.1_53723001_2 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001158899.1_53723001_2 - 0.017 14.5 0.1 0.073 12.5 0.1 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001158899.1_53723001_2 - 0.066 12.5 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.4 001158899.1_53723001_2 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF241 PF03087.12 001149040.1_53723001_1 - 0.082 12.6 0.0 2.3 7.9 0.0 2.3 1 1 0 1 1 1 0 Arabidopsis protein of unknown function DUF793 PF05633.9 001149040.1_53723001_1 - 0.13 11.1 0.9 0.48 9.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF793) Myb_DNA-binding PF00249.29 001146920.1_53724001_1 - 6.8e-27 93.2 6.5 2.8e-13 49.7 2.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001146920.1_53724001_1 - 1.3e-18 66.9 3.0 2.5e-13 49.9 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001146920.1_53724001_1 - 0.043 13.7 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 SLIDE Amino_oxidase PF01593.22 001154583.1_53725001_2 - 6.6e-21 75.0 0.0 9.5e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001154583.1_53725001_2 - 5.7e-13 48.8 0.9 1.6e-12 47.3 0.4 2.1 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001154583.1_53725001_2 - 3.1e-08 33.5 0.8 7.1e-06 25.7 1.6 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.22 001154583.1_53725001_2 - 3.6e-08 32.8 5.6 6.3e-06 25.4 3.1 2.8 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.12 001154583.1_53725001_2 - 2.8e-05 23.4 1.4 0.00024 20.3 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.5 001154583.1_53725001_2 - 0.00013 21.4 3.6 0.00013 21.3 1.8 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.20 001154583.1_53725001_2 - 0.00025 20.1 0.3 0.011 14.7 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.12 001154583.1_53725001_2 - 0.00026 19.7 1.6 0.0018 16.9 0.8 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.15 001154583.1_53725001_2 - 0.00045 19.4 0.2 0.001 18.2 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.17 001154583.1_53725001_2 - 0.0021 17.2 0.3 0.0033 16.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.17 001154583.1_53725001_2 - 0.006 15.9 0.2 0.052 12.8 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GDI PF00996.16 001154583.1_53725001_2 - 0.025 13.0 0.1 2.5 6.4 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox PF00070.25 001154583.1_53725001_2 - 5.6 7.5 6.9 4.4 7.8 0.7 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Formyl_trans_N PF00551.17 001146922.1_53723001_2 - 1.6e-54 184.3 0.0 2e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase HSF_DNA-bind PF00447.15 001153064.1_53724001_2 - 2.1e-28 98.6 0.1 3.4e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding PSI_PSAK PF01241.16 001158908.1_53722001_1 - 2.1e-25 88.6 0.8 3.4e-25 88.0 0.8 1.3 1 0 0 1 1 1 1 Photosystem I psaG / psaK peroxidase PF00141.21 001147663.1_53723001_3 - 4e-74 249.0 0.1 5.5e-74 248.6 0.1 1.2 1 0 0 1 1 1 1 Peroxidase Myb_DNA-binding PF00249.29 001146928.1_53723001_2 - 2e-31 107.8 0.9 1.6e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001146928.1_53723001_2 - 1.5e-18 66.6 0.0 7.2e-10 38.8 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain G_path_suppress PF15991.3 001147418.1_53723001_1 - 1.7 8.6 3.8 3.1 7.7 3.8 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor Myb_DNA-binding PF00249.29 001147418.1_53723001_3 - 2.3e-31 107.6 1.1 9.7e-15 54.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001147418.1_53723001_3 - 1e-19 70.4 0.5 1.1e-12 47.9 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001147418.1_53723001_3 - 0.0065 16.3 0.2 1.4 8.9 0.0 2.6 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.3 001147418.1_53723001_3 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 Myb DNA-binding like Abhydrolase_6 PF12697.5 001156365.1_53724001_2 - 8.6e-25 88.5 0.7 1.9e-24 87.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001156365.1_53724001_2 - 4e-13 49.1 0.2 5.6e-13 48.6 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.18 001156365.1_53724001_2 - 1.1e-12 48.0 0.0 3.1e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.18 001156365.1_53724001_2 - 2e-08 34.5 0.0 3.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.11 001156365.1_53724001_2 - 4.5e-06 26.4 0.2 6.8e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.18 001156365.1_53724001_2 - 5.3e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.11 001156365.1_53724001_2 - 0.0039 16.9 0.1 0.0078 16.0 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase Chlorophyllase2 PF12740.5 001156365.1_53724001_2 - 0.0084 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.23 001156365.1_53724001_2 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.7 001156365.1_53724001_2 - 0.044 13.2 0.1 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.5 001156365.1_53724001_2 - 0.051 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.6 001156365.1_53724001_2 - 0.058 12.8 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.11 001156365.1_53724001_2 - 0.072 12.8 1.6 0.69 9.6 1.6 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.12 001156365.1_53724001_2 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UBX PF00789.18 001149927.1_53723001_3 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Glyco_transf_8 PF01501.18 001148148.1_53724001_3 - 6.3e-51 173.2 0.0 7.7e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 RNA_pol_Rpb5_C PF01191.17 001148381.1_53724001_3 - 3.9e-28 96.9 0.1 6.7e-28 96.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.12 001148381.1_53724001_3 - 8.9e-20 70.9 0.0 1.6e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain HLH PF00010.24 001148618.1_53723001_2 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tom22 PF04281.11 001148618.1_53723001_2 - 0.049 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NMT_C PF02799.13 001155355.1_53724001_2 - 4.4e-78 261.5 0.1 5.8e-78 261.1 0.1 1.1 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.17 001155355.1_53724001_2 - 2.5e-74 248.3 0.0 3.7e-74 247.8 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.5 001155355.1_53724001_2 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.23 001155355.1_53724001_2 - 0.0039 17.3 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family HMG_box PF00505.17 001150736.1_53724001_2 - 1.4e-47 159.8 38.8 8.2e-18 64.5 4.3 4.5 5 0 0 5 5 5 3 HMG (high mobility group) box HMG_box_2 PF09011.8 001150736.1_53724001_2 - 6.3e-32 109.9 37.8 2.8e-13 50.1 4.6 4.8 4 0 0 4 4 4 3 HMG-box domain CHDNT PF08073.10 001150736.1_53724001_2 - 3.8e-05 23.4 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain KRAB PF01352.25 001150736.1_53724001_2 - 0.1 12.1 0.9 0.36 10.4 0.0 2.4 2 0 0 2 2 2 0 KRAB box Myco_19_kDa PF05481.10 001150736.1_53724001_2 - 0.26 11.1 2.8 0.61 9.9 2.8 1.5 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen PAP2 PF01569.19 001147673.1_53724001_2 - 1.7e-29 102.2 1.5 1.7e-29 102.2 1.5 2.0 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.4 001147673.1_53724001_2 - 3.3 7.2 11.8 0.041 13.4 2.9 2.3 2 1 0 2 2 2 0 PAP2 superfamily UPF0121 PF03661.11 001149932.1_53723001_3 - 2e-15 56.6 11.6 2.8e-15 56.2 11.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF3309 PF11752.6 001149932.1_53723001_3 - 0.087 12.7 0.4 0.23 11.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) SURF2 PF05477.9 001156372.1_53723001_1 - 3.5e-54 183.7 2.5 4.8e-54 183.2 2.5 1.1 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) Arginase PF00491.19 001147174.1_53723001_2 - 1.6e-66 224.5 0.0 2.4e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Arginase family CDC50 PF03381.13 001153324.1_53724001_1 - 3.5e-80 269.3 0.0 5.7e-80 268.6 0.0 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family OST3_OST6 PF04756.11 001153324.1_53724001_1 - 0.062 12.5 0.1 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Lipase_3 PF01764.23 001157140.1_53723001_2 - 8.8e-33 113.0 0.0 1.4e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.6 001157140.1_53723001_2 - 6.2e-05 22.3 0.0 0.015 14.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.18 001157140.1_53723001_2 - 0.00022 20.9 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.6 001157140.1_53723001_2 - 0.0012 18.4 0.1 0.0097 15.3 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.5 001157140.1_53723001_2 - 0.0071 16.9 0.1 0.016 15.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.18 001157140.1_53723001_2 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.18 001157140.1_53723001_2 - 0.036 14.0 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.12 001157140.1_53723001_2 - 0.046 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.11 001157140.1_53723001_2 - 0.049 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein TMEM95 PF15203.4 001157140.1_53723001_2 - 0.1 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 TMEM95 family BTB PF00651.29 001147179.1_53724001_1 - 2.1e-14 53.6 0.4 9e-13 48.3 0.0 3.5 2 1 1 3 3 3 1 BTB/POZ domain Ank_2 PF12796.5 001147179.1_53724001_1 - 2.2e-12 47.2 0.2 6.9e-12 45.7 0.2 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.4 001147179.1_53724001_1 - 7.7e-11 41.1 1.3 0.00053 20.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.4 001147179.1_53724001_1 - 2.1e-10 40.5 1.9 3e-07 30.5 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.28 001147179.1_53724001_1 - 4.9e-09 36.1 4.3 0.00022 21.4 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.4 001147179.1_53724001_1 - 1.1e-08 35.3 0.2 0.00048 20.5 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3420 PF11900.6 001147179.1_53724001_1 - 4.9e-08 32.8 3.0 1.1e-07 31.7 3.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3420) Ank_2 PF12796.5 001151659.1_53726001_1 - 4e-32 110.5 2.1 7.1e-08 32.8 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001151659.1_53726001_1 - 7.5e-27 92.9 17.7 4.4e-07 30.0 0.2 8.7 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.4 001151659.1_53726001_1 - 2.6e-23 82.0 4.9 2.6e-09 37.3 0.0 7.0 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.28 001151659.1_53726001_1 - 1.6e-17 62.9 8.3 0.0018 18.5 0.1 8.3 9 0 0 9 9 9 3 Ankyrin repeat Ank_3 PF13606.4 001151659.1_53726001_1 - 6.3e-16 56.7 7.5 0.62 10.7 0.0 9.0 9 0 0 9 9 9 4 Ankyrin repeat Retrotrans_gag PF03732.15 001153330.1_53723001_2 - 0.14 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_5 PF14787.4 001153330.1_53723001_2 - 0.2 11.2 2.1 0.46 10.1 2.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger gag_pre-integrs PF13976.4 001153330.1_53723001_3 - 7.8e-15 54.4 1.6 1.5e-14 53.4 1.6 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain PFK PF00365.18 001154608.1_53725001_2 - 1.1e-63 215.1 0.5 1.5e-63 214.7 0.5 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.22 001154608.1_53725001_2 - 0.0058 16.1 0.4 0.013 15.0 0.4 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.19 001154608.1_53725001_2 - 0.12 11.4 0.2 0.19 10.7 0.2 1.3 1 0 0 1 1 1 0 ATP-NAD kinase PPR PF01535.18 001153332.1_53723001_2 - 0.0003 20.7 0.0 0.00094 19.1 0.0 1.8 1 0 0 1 1 1 1 PPR repeat PPR_2 PF13041.4 001153332.1_53723001_2 - 0.0024 17.9 0.0 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 PPR repeat family AFG1_ATPase PF03969.14 001153332.1_53723001_2 - 0.032 13.0 0.3 0.33 9.7 0.3 2.0 2 0 0 2 2 2 0 AFG1-like ATPase Pmp3 PF01679.15 001159476.1_53721001_3 - 4e-18 65.2 10.0 6e-18 64.7 10.0 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Transferase PF02458.13 001152399.1_53725001_1 - 3.3e-99 332.3 0.0 4.1e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 Transferase family FGF-BP1 PF06473.10 001151491.1_53722001_3 - 2.5 7.8 5.7 0.84 9.3 2.8 1.6 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) OPT PF03169.13 001152400.1_53725001_3 - 4.6e-127 425.1 28.7 5.3e-127 424.9 28.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PRIMA1 PF16101.3 001152400.1_53725001_3 - 1.5 8.7 9.1 0.67 9.9 3.3 2.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Pkinase PF00069.23 001153586.1_53725001_2 - 1.4e-46 158.9 0.0 2e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001153586.1_53725001_2 - 4.4e-46 157.1 0.0 6.2e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GUB_WAK_bind PF13947.4 001153586.1_53725001_2 - 3.7e-29 101.5 0.3 1e-28 100.1 0.3 1.8 1 0 0 1 1 1 1 Wall-associated receptor kinase galacturonan-binding EGF_CA PF07645.13 001153586.1_53725001_2 - 4.2e-05 23.5 4.9 4.2e-05 23.5 4.9 2.8 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.25 001153586.1_53725001_2 - 0.0018 18.4 13.6 0.068 13.4 3.6 3.5 2 1 0 2 2 2 2 EGF-like domain cEGF PF12662.5 001153586.1_53725001_2 - 0.0038 17.0 10.9 0.012 15.4 2.8 3.1 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.5 001153586.1_53725001_2 - 1.6 8.8 20.8 0.38 10.9 1.7 3.8 3 0 0 3 3 3 0 EGF domain FXa_inhibition PF14670.4 001153586.1_53725001_2 - 6.2 7.1 23.6 0.26 11.5 4.9 3.8 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site WRKY PF03106.13 001154865.1_53722001_2 - 1.2e-24 86.3 5.0 2.4e-24 85.3 5.0 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain FAR1 PF03101.13 001154865.1_53722001_2 - 0.0097 16.5 0.1 0.016 15.8 0.1 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain Sugar_tr PF00083.22 001147686.1_53725001_1 - 9.7e-100 334.4 15.9 1.5e-99 333.8 15.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001147686.1_53725001_1 - 9.2e-25 87.2 30.0 9.2e-25 87.2 30.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF948 PF06103.9 001150538.1_53724001_3 - 0.18 12.0 6.8 0.16 12.1 2.2 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.10 001150538.1_53724001_3 - 0.35 10.8 9.1 2.2 8.2 4.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.9 001150538.1_53724001_3 - 0.46 10.8 14.7 0.26 11.6 1.2 3.7 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.10 001150538.1_53724001_3 - 0.47 9.7 9.1 2.7 7.2 2.1 2.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Cep57_CLD_2 PF14197.4 001150538.1_53724001_3 - 1.5 8.8 28.6 3.9 7.5 2.0 4.5 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF972 PF06156.11 001150538.1_53724001_3 - 2.4 8.7 26.6 2.2 8.8 5.0 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF972) DUF2730 PF10805.6 001150538.1_53724001_3 - 3.2 7.7 11.0 4.4 7.3 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) JIP_LZII PF16471.3 001150538.1_53724001_3 - 4.7 7.3 25.8 0.5 10.4 3.5 5.0 3 1 2 5 5 5 0 JNK-interacting protein leucine zipper II Glucosamine_iso PF01182.18 001155879.1_53723001_2 - 5.6e-64 216.0 0.0 6.7e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar_tr PF00083.22 001157918.1_53724001_1 - 1.8e-102 343.4 18.0 2.1e-102 343.2 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001157918.1_53724001_1 - 3.2e-30 105.1 32.9 4.7e-29 101.3 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhK PF14145.4 001157918.1_53724001_1 - 0.19 11.7 0.1 0.19 11.7 0.1 4.1 5 0 0 5 5 5 0 YrhK-like protein TPR_14 PF13428.4 001146951.1_53723001_2 - 2.3e-06 27.8 7.2 0.068 13.9 1.6 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.4 001146951.1_53723001_2 - 3.5e-05 23.8 0.4 0.18 12.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.15 001146951.1_53723001_2 - 0.00012 21.8 1.5 0.2 11.7 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.26 001146951.1_53723001_2 - 0.0086 15.7 0.2 4.1 7.2 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.4 001146951.1_53723001_2 - 0.0091 16.5 8.6 0.094 13.3 7.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.4 001146951.1_53723001_2 - 0.029 14.4 4.9 0.43 10.7 0.8 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.4 001146951.1_53723001_2 - 0.084 12.8 1.2 4.1 7.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.4 001146951.1_53723001_2 - 0.16 12.1 0.0 4.2 7.7 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.4 001146951.1_53723001_2 - 0.18 12.2 3.0 5.6 7.4 2.6 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.29 001155880.1_53723001_2 - 4.8e-21 74.5 0.0 1.1e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPT PF03151.14 001157663.1_53723001_1 - 6.8e-46 156.8 24.7 8.3e-46 156.5 24.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.9 001157663.1_53723001_1 - 4.7e-16 58.7 24.2 6.6e-16 58.2 24.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.18 001157663.1_53723001_1 - 6.8e-09 35.9 33.7 4.9e-05 23.4 14.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family Thiolase_N PF00108.21 001148402.1_53724001_2 - 6.2e-89 297.7 0.3 1e-88 296.9 0.1 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.16 001148402.1_53724001_2 - 3.5e-41 139.6 0.9 7.2e-41 138.6 0.9 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.24 001148402.1_53724001_2 - 2.1e-05 24.1 0.7 2.1e-05 24.1 0.7 2.2 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.8 001148402.1_53724001_2 - 0.18 11.5 3.9 5.4 6.8 0.2 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF239 PF03080.13 001146953.1_53726001_2 - 3e-86 288.3 8.2 4.9e-86 287.6 8.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF239) DUF4409 PF14365.4 001146953.1_53726001_2 - 3.6e-46 156.3 0.1 6.9e-46 155.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4409) mTERF PF02536.12 001146953.1_53726001_3 - 5.8e-09 35.2 0.3 7.9e-09 34.8 0.3 1.1 1 0 0 1 1 1 1 mTERF Methyltr_RsmB-F PF01189.15 001157153.1_53724001_1 - 1.4e-30 106.3 0.0 5.1e-20 71.8 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.17 001157153.1_53724001_1 - 5.4e-05 23.2 0.1 0.00069 19.6 0.1 2.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.4 001157153.1_53724001_1 - 7.8e-05 22.4 0.1 0.0058 16.3 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.4 001157153.1_53724001_1 - 0.0012 19.3 0.0 0.0036 17.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.16 001157153.1_53724001_1 - 0.17 11.0 0.0 0.47 9.6 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DnaJ_C PF01556.16 001155630.1_53723001_1 - 1.6e-38 132.0 0.0 2.3e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 001155630.1_53723001_1 - 9.8e-28 95.9 1.0 5.2e-27 93.6 1.1 2.1 2 0 0 2 2 2 1 DnaJ domain Glyco_hydro_17 PF00332.16 001153854.1_53724001_1 - 2.1e-78 263.8 0.0 2.5e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 ALAD PF00490.19 001153854.1_53724001_1 - 0.16 11.0 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Glyco_transf_5 PF08323.9 001288048.1_48626001_1 - 7.5e-64 215.6 0.0 1.1e-63 215.0 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 001288048.1_48626001_1 - 2.1e-16 59.8 0.0 3.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001288048.1_48626001_1 - 1.3e-14 54.6 0.0 2.2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001288048.1_48626001_1 - 0.00028 20.8 0.0 0.0068 16.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.4 001288048.1_48626001_1 - 0.0014 19.0 0.1 0.0065 16.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Cupin_3 PF05899.10 001156904.1_53722001_3 - 2.4e-31 107.0 0.8 4.1e-31 106.3 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.10 001156904.1_53722001_3 - 0.00027 20.6 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.9 001156904.1_53722001_3 - 0.0023 17.4 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.5 001156904.1_53722001_3 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.20 001156904.1_53722001_3 - 0.057 12.9 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin Ras PF00071.20 001148891.1_53723001_2 - 1.1e-56 190.8 0.2 1.5e-56 190.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001148891.1_53723001_2 - 5.6e-36 123.3 0.1 8.2e-36 122.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001148891.1_53723001_2 - 1.5e-14 53.7 0.1 1.9e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001148891.1_53723001_2 - 1.8e-05 24.1 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001148891.1_53723001_2 - 2e-05 23.9 0.2 2.8e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001148891.1_53723001_2 - 3.4e-05 23.3 0.1 0.00011 21.7 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001148891.1_53723001_2 - 0.00061 19.6 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001148891.1_53723001_2 - 0.00062 19.7 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.16 001148891.1_53723001_2 - 0.003 17.0 0.1 0.051 13.0 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B FKBP_C PF00254.26 001156906.1_53722001_1 - 3.6e-15 55.9 0.0 6.4e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Spt20 PF12090.6 001156906.1_53722001_1 - 0.71 9.3 5.2 1.1 8.7 5.2 1.2 1 0 0 1 1 1 0 Spt20 family zf-FLZ PF04570.12 001146733.2_53723001_3 - 3.3e-23 80.8 0.7 7.1e-23 79.7 0.7 1.6 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 Opiods_neuropep PF01160.16 001146733.2_53723001_3 - 0.034 14.1 0.6 0.077 13.0 0.6 1.6 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide bZIP_1 PF00170.19 001154368.1_53723001_1 - 6.3e-07 29.3 12.4 6.3e-07 29.3 12.4 2.8 3 1 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.13 001154368.1_53723001_1 - 0.00012 22.0 5.9 0.00012 22.0 5.9 3.4 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_Maf PF03131.15 001154368.1_53723001_1 - 7.4 7.0 21.1 0.54 10.7 10.4 2.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Cas_CXXC_CXXC PF09706.8 001154368.1_53723001_3 - 0.0015 18.6 0.7 0.003 17.6 0.7 1.5 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_CXXC_CXXC) MatE PF01554.16 001148896.1_53724001_3 - 2.1e-65 219.1 34.8 4.7e-34 117.2 14.9 2.3 2 0 0 2 2 2 2 MatE FUN14 PF04930.13 001148896.1_53724001_3 - 0.038 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 FUN14 family Lysine_decarbox PF03641.12 001156150.1_53723001_1 - 1.4e-43 148.0 0.0 2.1e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase DUF2631 PF10939.6 001156150.1_53723001_2 - 0.056 13.2 0.9 0.13 12.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) 4HBT PF03061.20 001156659.1_53722001_2 - 1.3e-16 60.5 0.3 2.1e-16 59.9 0.3 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.4 001156659.1_53722001_2 - 0.00017 21.8 0.1 0.00025 21.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Zip PF02535.20 001156151.1_53723001_1 - 1.8e-64 217.9 3.6 2.2e-64 217.7 3.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Peptidase_S10 PF00450.20 001157680.1_53724001_1 - 1.2e-119 400.3 0.0 1.4e-119 400.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4378 PF14309.4 001149622.1_53725001_3 - 1.3e-18 67.8 0.0 2.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) Pkinase PF00069.23 001154121.1_53726001_2 - 1.9e-43 148.6 0.0 2.9e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001154121.1_53726001_2 - 1.4e-40 139.1 0.0 2.5e-40 138.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase B_lectin PF01453.22 001154121.1_53726001_2 - 7.8e-12 45.0 4.9 3.4e-08 33.3 0.4 2.5 1 1 1 2 2 2 2 D-mannose binding lectin S_locus_glycop PF00954.18 001154121.1_53726001_2 - 2.6e-06 27.8 0.1 1.6e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 S-locus glycoprotein domain hEGF PF12661.5 001154121.1_53726001_2 - 0.00016 22.0 5.0 0.00016 22.0 5.0 2.2 2 0 0 2 2 2 1 Human growth factor-like EGF Kinase-like PF14531.4 001154121.1_53726001_2 - 0.0002 20.6 0.0 0.00032 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PAN_2 PF08276.9 001154121.1_53726001_2 - 0.0022 17.9 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.4 001154121.1_53726001_2 - 0.0025 17.5 0.1 0.0075 16.0 0.1 1.8 1 0 0 1 1 1 1 PAN domain EGF PF00008.25 001154121.1_53726001_2 - 0.0027 17.8 5.2 0.0027 17.8 5.2 2.5 3 0 0 3 3 3 1 EGF-like domain EB PF01683.16 001154121.1_53726001_2 - 0.015 15.4 0.9 0.015 15.4 0.9 3.0 3 0 0 3 3 3 0 EB module PIP49_C PF12260.6 001154121.1_53726001_2 - 0.038 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 cEGF PF12662.5 001154121.1_53726001_2 - 0.087 12.7 2.7 0.28 11.0 2.7 2.0 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_2 PF07974.11 001154121.1_53726001_2 - 4.4 7.6 8.0 0.19 12.0 1.7 2.0 2 0 0 2 2 2 0 EGF-like domain Thioredoxin PF00085.18 001147462.1_53723001_2 - 4.4e-06 26.4 0.0 8.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.14 001147462.1_53723001_2 - 0.00013 20.9 0.1 0.0002 20.3 0.1 1.3 1 0 0 1 1 1 1 Phosducin DUF912 PF06024.10 001147462.1_53723001_2 - 0.14 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Gcd10p PF04189.11 001147462.1_53723001_2 - 0.19 10.7 1.4 0.33 9.9 1.4 1.3 1 0 0 1 1 1 0 Gcd10p family Mon1 PF03164.12 001155646.1_53724001_2 - 1.8e-140 468.5 0.1 2.1e-140 468.2 0.1 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Exostosin PF03016.13 001148185.1_53724001_2 - 8e-78 261.5 0.0 1.1e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 Exostosin family His_Phos_1 PF00300.20 001151134.1_53722001_2 - 0.075 12.6 0.3 0.099 12.2 0.3 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) RNase_T PF00929.22 001147212.1_53723001_2 - 0.038 14.4 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 Exonuclease DnaJ PF00226.29 001152877.1_53727001_3 - 0.00045 20.2 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain IU_nuc_hydro PF01156.17 001155143.1_53723001_3 - 3.5e-78 263.1 0.0 4.2e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase NifU PF01106.15 001155143.1_53723001_3 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 NifU-like domain Pollen_Ole_e_I PF01190.15 001155144.1_53723001_1 - 8.1e-10 38.8 0.4 1.2e-09 38.2 0.4 1.2 1 0 0 1 1 1 1 Pollen proteins Ole e I like Lipase_GDSL PF00657.20 001157432.1_53723001_3 - 3e-16 59.9 0.0 4.3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.4 001157432.1_53723001_3 - 0.0011 19.3 0.0 0.0046 17.2 0.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1459 PF07312.9 001157432.1_53723001_3 - 0.029 14.5 1.1 5.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) FAD_binding_2 PF00890.22 001152880.1_53725001_2 - 2.7e-124 415.3 3.6 3.2e-124 415.1 3.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.18 001152880.1_53725001_2 - 1.2e-43 148.1 0.7 1.7e-43 147.5 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.12 001152880.1_53725001_2 - 0.00013 21.1 0.2 0.00025 20.3 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001152880.1_53725001_2 - 0.00065 18.8 1.0 0.04 12.9 1.7 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.15 001152880.1_53725001_2 - 0.00086 18.5 0.5 0.18 10.9 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.17 001152880.1_53725001_2 - 0.0028 16.8 0.3 0.0049 16.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.22 001152880.1_53725001_2 - 0.022 14.2 0.8 0.039 13.4 0.8 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.12 001152880.1_53725001_2 - 0.083 11.4 1.0 0.17 10.4 0.4 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.4 001152880.1_53725001_2 - 0.56 9.2 1.8 1.5 7.9 0.8 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF547 PF04784.12 001158964.1_53725001_2 - 3.8e-31 107.3 0.0 7.7e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Lzipper-MIP1 PF14389.4 001158964.1_53725001_2 - 7.7e-23 80.4 0.1 2.1e-22 79.0 0.1 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 LRR_8 PF13855.4 001153123.1_53726001_1 - 1e-35 121.1 37.6 2.6e-09 36.6 0.5 8.0 3 3 5 9 9 9 9 Leucine rich repeat Pkinase_Tyr PF07714.15 001153123.1_53726001_1 - 7e-30 104.0 0.0 1.7e-29 102.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.5 001153123.1_53726001_1 - 4.4e-28 96.6 27.8 7.9e-06 26.0 0.8 9.5 5 3 2 10 10 10 9 Leucine Rich repeats (2 copies) Pkinase PF00069.23 001153123.1_53726001_1 - 4.1e-26 91.8 0.0 6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_1 PF00560.31 001153123.1_53726001_1 - 1.1e-11 43.3 28.4 5.5 7.7 0.2 14.0 14 0 0 14 14 14 2 Leucine Rich Repeat LRR_6 PF13516.4 001153123.1_53726001_1 - 2.4e-06 27.0 33.4 9.1 6.5 0.0 11.6 14 0 0 14 14 14 4 Leucine Rich repeat LRRNT_2 PF08263.10 001153123.1_53726001_1 - 0.00058 19.9 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Dirigent PF03018.12 001156165.1_53722001_1 - 1.8e-24 86.2 0.5 2.3e-24 85.9 0.5 1.1 1 0 0 1 1 1 1 Dirigent-like protein DUF4349 PF14257.4 001159468.1_53723001_3 - 1.5 8.1 6.5 2.1 7.6 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Sugar_tr PF00083.22 001156420.1_53724001_3 - 6.1e-43 147.2 12.3 1.6e-42 145.8 12.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001156420.1_53724001_3 - 4.1e-16 58.7 24.4 9.4e-16 57.5 23.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.4 001156420.1_53724001_3 - 0.22 11.0 6.0 7 6.1 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Glyco_hydro_28 PF00295.15 001157440.1_53724001_3 - 2.9e-83 279.5 4.2 4.2e-83 278.9 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.5 001157440.1_53724001_3 - 1.4e-08 34.8 13.5 8.5e-08 32.2 8.3 3.0 1 1 1 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.4 001157440.1_53724001_3 - 0.0037 17.0 12.0 0.0037 17.0 12.0 2.3 1 1 1 2 2 2 2 Right handed beta helix region End_N_terminal PF12218.6 001157440.1_53724001_3 - 0.27 10.8 1.1 0.71 9.5 0.3 2.0 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase zf-RanBP PF00641.16 001153625.1_53724001_3 - 9.4e-06 24.7 6.8 1.5e-05 24.0 6.8 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Trypan_PARP PF05887.9 001153625.1_53724001_3 - 0.51 10.2 10.8 1.4 8.8 10.8 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HLH PF00010.24 001157953.1_53723001_2 - 1.6e-08 34.3 3.3 1.6e-08 34.3 3.3 2.5 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain FhuF PF06276.10 001157953.1_53723001_2 - 0.032 14.5 0.1 0.055 13.7 0.1 1.4 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter peroxidase PF00141.21 001158468.1_53723001_2 - 3.7e-78 262.2 0.2 5.1e-78 261.8 0.2 1.2 1 0 0 1 1 1 1 Peroxidase DUF4604 PF15377.4 001158468.1_53723001_2 - 0.32 11.3 19.1 0.51 10.6 19.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Connexin PF00029.17 001158468.1_53723001_2 - 2.1 7.9 4.6 3.7 7.1 4.6 1.4 1 0 0 1 1 1 0 Connexin Ribosomal_L35p PF01632.17 001156176.1_53722001_1 - 5.5e-14 52.3 8.1 5.5e-14 52.3 8.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L35 Lectin_legB PF00139.17 001147965.1_53725001_3 - 2.9e-80 269.3 0.0 4.2e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 Legume lectin domain Pkinase PF00069.23 001147965.1_53725001_3 - 5.7e-52 176.5 0.0 7.6e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001147965.1_53725001_3 - 2.1e-41 141.8 0.0 3e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001147965.1_53725001_3 - 0.0028 17.5 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Lectin_leg-like PF03388.11 001147965.1_53725001_3 - 0.0059 15.8 0.4 1.5 8.0 0.1 2.3 2 0 0 2 2 2 2 Legume-like lectin family Kinase-like PF14531.4 001147965.1_53725001_3 - 0.017 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like KNOX2 PF03791.11 001156179.1_53724001_1 - 4.2e-24 83.8 0.2 4.2e-24 83.8 0.2 1.8 2 0 0 2 2 2 1 KNOX2 domain KNOX1 PF03790.11 001156179.1_53724001_1 - 1.3e-21 75.9 1.1 2.3e-21 75.1 1.1 1.4 1 0 0 1 1 1 1 KNOX1 domain Homeobox_KN PF05920.9 001156179.1_53724001_1 - 9.3e-17 60.5 2.6 2e-16 59.4 2.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain ELK PF03789.11 001156179.1_53724001_1 - 7.4e-10 38.5 5.4 7.4e-10 38.5 5.4 1.8 2 0 0 2 2 2 1 ELK domain Homeobox PF00046.27 001156179.1_53724001_1 - 3.4e-07 29.8 0.8 7.4e-07 28.8 0.6 1.7 1 1 0 1 1 1 1 Homeobox domain IATP PF04568.10 001156179.1_53724001_1 - 0.018 15.3 0.4 0.06 13.6 0.4 1.9 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP SUI1 PF01253.20 001153895.1_53722001_3 - 5.3e-20 71.6 0.7 8.4e-20 71.0 0.7 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 F-box-like PF12937.5 001148211.1_53724001_3 - 1.6e-09 37.3 0.1 7.1e-09 35.3 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001148211.1_53724001_3 - 0.0003 20.4 6.0 0.00061 19.5 0.9 2.8 2 1 1 3 3 3 1 F-box domain Cyclin_N PF00134.21 001156438.1_53723001_3 - 5.6e-29 100.4 0.0 8.2e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001156438.1_53723001_3 - 2e-05 24.5 0.0 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain Pkinase PF00069.23 001156185.1_53724001_3 - 8.9e-72 241.5 0.0 1.3e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001156185.1_53724001_3 - 1.6e-33 115.9 0.0 2.7e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001156185.1_53724001_3 - 0.018 14.8 0.0 0.049 13.4 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001156185.1_53724001_3 - 0.046 13.2 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.12 001156185.1_53724001_3 - 0.095 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.18 001151353.1_53725001_1 - 2.4e-24 85.4 0.0 3.1e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.18 001151353.1_53725001_3 - 6.8e-166 552.8 0.0 8.5e-166 552.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001151353.1_53725001_3 - 2e-12 46.4 0.2 4.4e-11 42.1 0.0 2.4 2 1 0 2 2 2 1 MreB/Mbl protein DDR PF08841.8 001151353.1_53725001_3 - 0.012 14.4 0.3 4.2 6.1 0.2 2.4 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.4 001151353.1_53725001_3 - 0.014 15.7 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 0 Cell division protein FtsA LBP_BPI_CETP_C PF02886.15 001154671.1_53724001_2 - 2.6e-28 98.9 0.8 1.6e-27 96.3 0.0 2.4 3 0 0 3 3 3 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.23 001154671.1_53724001_2 - 1.4e-21 76.7 0.1 1.1e-20 73.7 0.1 2.2 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.9 001154671.1_53724001_2 - 0.0021 17.2 0.0 0.082 11.9 0.0 2.2 1 1 1 2 2 2 2 Haemolymph juvenile hormone binding protein (JHBP) Fe-S_biosyn PF01521.18 001154920.1_53722001_2 - 1.1e-18 67.3 0.0 1.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Patatin PF01734.20 001157718.1_53724001_3 - 4.6e-22 79.0 0.1 7.8e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase VHS PF00790.17 001157974.1_53725001_3 - 1e-35 122.5 0.1 2.3e-35 121.3 0.1 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.12 001157974.1_53725001_3 - 1.1e-19 70.4 0.1 3.1e-19 68.9 0.1 1.8 1 0 0 1 1 1 1 GAT domain ENTH PF01417.18 001157974.1_53725001_3 - 0.00016 21.6 0.4 0.0003 20.7 0.4 1.4 1 0 0 1 1 1 1 ENTH domain DUF3730 PF12530.6 001157974.1_53725001_3 - 0.00042 19.8 0.0 0.001 18.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) APG17 PF04108.10 001157974.1_53725001_3 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF566 PF04484.10 001149834.1_53724001_2 - 3e-70 237.2 0.6 3e-70 237.2 0.6 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF566) DUF4611 PF15387.4 001151879.1_53725001_2 - 6.9 6.8 14.9 25 5.1 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4611) Cation_efflux PF01545.19 001157464.1_53723001_1 - 4.8e-30 104.7 7.1 6e-30 104.3 7.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.3 001157464.1_53723001_1 - 3.2e-14 52.7 0.1 5.9e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter NMN_transporter PF04973.10 001157464.1_53723001_1 - 0.035 13.9 0.6 0.035 13.9 0.6 2.3 2 1 0 2 2 2 0 Nicotinamide mononucleotide transporter TMIE PF16038.3 001157464.1_53723001_1 - 0.049 13.4 0.7 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 TMIE protein LRRC37 PF15779.3 001154923.1_53722001_1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat-containing protein 37 family Ribosomal_L5 PF00281.17 001154923.1_53722001_2 - 1.3e-20 73.3 0.0 2.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.19 001154923.1_53722001_2 - 2.3e-20 72.4 0.0 3.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus PPR PF01535.18 001148455.1_53725001_3 - 1e-57 188.3 7.4 4.6e-08 32.7 0.0 13.5 13 0 0 13 13 13 10 PPR repeat PPR_2 PF13041.4 001148455.1_53725001_3 - 2.3e-57 190.9 1.0 1.2e-09 38.1 0.0 10.8 9 1 2 11 11 11 9 PPR repeat family PPR_1 PF12854.5 001148455.1_53725001_3 - 9.4e-32 108.3 6.5 0.00015 21.3 0.0 10.5 11 0 0 11 11 11 7 PPR repeat PPR_3 PF13812.4 001148455.1_53725001_3 - 8.8e-13 48.0 0.0 0.096 12.6 0.0 8.5 5 3 4 10 10 9 2 Pentatricopeptide repeat domain PPR_long PF17177.2 001148455.1_53725001_3 - 9.5e-10 38.1 0.2 0.033 13.4 0.0 4.1 2 2 0 3 3 3 3 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001148455.1_53725001_3 - 0.0017 18.9 4.8 5 8.1 0.0 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat Ribosomal_L32e PF01655.16 001153150.1_53722001_2 - 4.2e-47 158.9 0.5 5.6e-47 158.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 LSM PF01423.20 001157211.1_53722001_2 - 4.8e-15 54.9 0.1 7e-15 54.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.4 001157211.1_53722001_2 - 0.026 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain G6PD_C PF02781.14 001157212.1_53724001_1 - 4.2e-115 383.8 0.0 5.7e-115 383.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.20 001157212.1_53724001_1 - 3e-56 190.7 0.0 4.6e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Pkinase_Tyr PF07714.15 001157724.1_53723001_2 - 3e-48 164.2 0.0 4.2e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001157724.1_53723001_2 - 5.1e-45 153.8 0.0 6.4e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ABC1 PF03109.14 001157724.1_53723001_2 - 0.0012 18.8 0.0 0.0035 17.4 0.0 1.6 2 0 0 2 2 2 1 ABC1 family DUF707 PF05212.10 001156960.1_53724001_3 - 1.3e-138 461.1 0.7 1.7e-138 460.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF707) LRR_4 PF12799.5 001148458.2_53725001_1 - 2.4e-39 132.4 72.7 6.8e-05 23.0 2.3 12.6 8 2 3 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001148458.2_53725001_1 - 5.4e-37 125.2 79.1 1.4e-08 34.3 2.7 10.2 5 3 7 13 13 13 12 Leucine rich repeat LRR_1 PF00560.31 001148458.2_53725001_1 - 4.3e-17 59.7 71.3 0.3 11.6 0.2 20.1 18 3 1 19 19 19 10 Leucine Rich Repeat LRRNT_2 PF08263.10 001148458.2_53725001_1 - 3.9e-08 33.3 0.5 3.9e-08 33.3 0.5 2.4 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_2 PF07723.11 001148458.2_53725001_1 - 0.0029 18.1 7.1 37 5.1 0.0 7.5 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_9 PF14580.4 001148458.2_53725001_1 - 0.048 13.0 8.2 1.2 8.5 0.1 3.4 2 1 2 4 4 4 0 Leucine-rich repeat MoaC PF01967.19 001155435.1_53723001_1 - 1.1e-49 167.7 3.0 1.4e-49 167.3 3.0 1.1 1 0 0 1 1 1 1 MoaC family Cellulose_synt PF03552.12 001154422.1_53725001_2 - 1.1e-134 450.5 0.1 1.5e-91 307.9 0.0 2.0 1 1 1 2 2 2 2 Cellulose synthase Glyco_tranf_2_3 PF13641.4 001154422.1_53725001_2 - 3.9e-07 30.1 0.0 0.00031 20.6 0.0 3.0 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Peptidase_M32 PF02074.13 001154422.1_53725001_2 - 0.043 12.7 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Isy1 PF06246.10 001155438.1_53723001_3 - 9.6e-88 293.9 11.1 1.2e-87 293.6 11.1 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Circo_capsid PF02443.13 001153914.1_53722001_1 - 0.98 8.8 12.0 1.2 8.5 12.0 1.1 1 0 0 1 1 1 0 Circovirus capsid protein Pneumo_att_G PF05539.9 001153914.1_53722001_1 - 5.9 6.3 15.0 7 6.0 15.0 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GLTT PF01744.18 001153914.1_53722001_2 - 0.00048 19.7 1.4 0.0013 18.3 1.4 1.8 1 0 0 1 1 1 1 GLTT repeat (6 copies) CYSTM PF12734.5 001153914.1_53722001_3 - 1.7e-14 53.7 19.2 1.7e-14 53.7 19.2 4.6 2 1 1 3 3 3 1 Cysteine-rich TM module stress tolerance DUF2076 PF09849.7 001153914.1_53722001_3 - 6.6 6.6 22.2 15 5.4 22.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Glyco_hydro_9 PF00759.17 001157986.1_53724001_3 - 2.2e-142 475.2 0.8 2.5e-142 475.0 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 TSP9 PF11493.6 001149842.1_53722001_1 - 1.6e-17 63.8 5.2 1.6e-17 63.8 5.2 2.3 1 1 1 2 2 2 1 Thylakoid soluble phosphoprotein TSP9 Pkinase_Tyr PF07714.15 001155948.1_53724001_1 - 6.7e-34 117.2 0.0 8.7e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001155948.1_53724001_1 - 1.5e-28 99.8 0.0 2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Peptidase_C97 PF05903.12 001146782.1_53723001_1 - 4.5e-44 149.8 0.1 5.7e-44 149.4 0.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.11 001146782.1_53723001_1 - 0.09 12.9 0.6 0.14 12.3 0.6 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase SYF2 PF08231.10 001148952.1_53723001_2 - 3.1e-37 128.3 18.2 3.1e-37 128.3 18.2 1.6 2 0 0 2 2 2 1 SYF2 splicing factor zf-TRAF PF02176.16 001155444.1_53723001_2 - 6.3e-05 23.4 19.3 0.0007 20.1 4.7 3.3 1 1 3 4 4 4 3 TRAF-type zinc finger PRP21_like_P PF12230.6 001155444.1_53723001_2 - 0.12 12.1 1.8 0.24 11.1 0.5 2.1 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein DiS_P_DiS PF06750.11 001155444.1_53723001_2 - 8.7 6.4 8.9 0.38 10.8 0.1 2.9 3 1 0 3 3 3 0 Bacterial Peptidase A24 N-terminal domain PsbW PF07123.10 001156714.1_53722001_2 - 6.5e-49 165.2 2.6 8.6e-49 164.8 2.6 1.1 1 0 0 1 1 1 1 Photosystem II reaction centre W protein (PsbW) ELMO_CED12 PF04727.11 001148705.1_53724001_2 - 7.9e-52 175.8 0.5 9.9e-52 175.5 0.5 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family Pkinase PF00069.23 001153162.1_53726001_3 - 1.4e-41 142.5 0.0 1.9e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001153162.1_53726001_3 - 8.4e-41 139.8 0.0 1.1e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRRNT_2 PF08263.10 001153162.1_53726001_3 - 3.6e-14 52.6 0.1 8.3e-14 51.5 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.4 001153162.1_53726001_3 - 3.4e-11 42.6 32.2 4.3e-06 26.3 8.5 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 001153162.1_53726001_3 - 1.9e-09 37.4 11.1 5.6e-05 23.3 1.3 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001153162.1_53726001_3 - 0.023 15.0 21.7 0.15 12.5 0.1 6.0 5 1 2 7 7 7 0 Leucine Rich Repeat APH PF01636.21 001153162.1_53726001_3 - 0.025 14.3 0.1 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family LRR_6 PF13516.4 001153162.1_53726001_3 - 0.15 12.0 0.1 0.15 12.0 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Cyclin_N PF00134.21 001156461.1_53724001_2 - 3.7e-43 146.2 0.7 6.3e-43 145.5 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001156461.1_53724001_2 - 6.2e-30 103.6 0.0 1.1e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain ALS_ss_C PF10369.7 001152686.1_53724001_2 - 6.8e-46 154.2 10.5 2.6e-24 85.1 0.6 3.0 3 0 0 3 3 3 2 Small subunit of acetolactate synthase ACT_5 PF13710.4 001152686.1_53724001_2 - 1.7e-27 94.9 0.1 2.4e-13 49.5 0.0 2.8 3 0 0 3 3 3 2 ACT domain ACT PF01842.23 001152686.1_53724001_2 - 2.4e-22 78.3 0.9 2.7e-10 39.7 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.4 001152686.1_53724001_2 - 8.2e-11 42.2 3.8 0.00015 22.1 0.6 3.2 3 0 0 3 3 3 2 ACT domain ACT_6 PF13740.4 001152686.1_53724001_2 - 0.047 13.5 0.5 7.7 6.4 0.0 3.6 4 0 0 4 4 4 0 ACT domain RRM_1 PF00076.20 001156467.1_53724001_3 - 1e-28 98.8 0.0 1.4e-15 56.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001156467.1_53724001_3 - 7.9e-10 38.6 0.0 0.00017 21.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif IU_nuc_hydro PF01156.17 001148476.1_53724001_1 - 5.5e-76 255.9 0.0 6.8e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Engrail_1_C_sig PF10525.7 001149680.1_53725001_2 - 4.9 6.3 4.7 1.9 7.7 0.2 2.1 2 0 0 2 2 2 0 Engrailed homeobox C-terminal signature domain Ribonuclease_3 PF00636.24 001148241.1_53723001_1 - 9.5e-22 77.5 0.0 6.9e-20 71.5 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.4 001148241.1_53723001_1 - 1.1e-19 70.8 0.0 3e-19 69.3 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.24 001148241.1_53723001_1 - 2.3e-05 24.8 0.0 8.8e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Double-stranded RNA binding motif FlgT_N PF16548.3 001148241.1_53723001_1 - 0.1 13.1 0.6 0.18 12.3 0.6 1.4 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain DUF572 PF04502.11 001148241.1_53723001_1 - 0.18 11.2 0.1 0.25 10.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3357 PF11837.6 001149295.1_53722001_3 - 0.71 10.2 0.0 0.71 10.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) G-patch PF01585.21 001155709.1_53724001_1 - 2.8e-14 52.6 3.8 2.9e-14 52.6 2.3 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.5 001155709.1_53724001_1 - 7.4e-05 22.6 2.1 0.00014 21.7 0.4 2.4 2 0 0 2 2 2 1 G-patch domain NAM-associated PF14303.4 001155709.1_53724001_1 - 7.8 7.0 13.3 0.11 13.0 2.1 2.4 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain BAP PF06639.9 001149296.1_53721001_1 - 4.1e-31 106.9 0.1 5.5e-31 106.5 0.1 1.2 1 0 0 1 1 1 1 Basal layer antifungal peptide (BAP) p450 PF00067.20 001148006.1_53724001_3 - 1.6e-88 297.4 0.0 2e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IF-2B PF01008.15 001156473.1_53723001_2 - 5.5e-66 222.5 0.0 6.5e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Per1 PF04080.11 001148481.1_53724001_2 - 4.9e-83 278.6 13.2 6.5e-83 278.2 13.2 1.1 1 0 0 1 1 1 1 Per1-like DUF760 PF05542.9 001152061.1_53724001_2 - 6.9e-30 103.1 0.0 4e-23 81.5 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF760) Arf PF00025.19 001152695.1_53722001_3 - 1e-65 220.3 0.0 1.2e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.18 001152695.1_53722001_3 - 5.9e-12 45.3 0.1 1.7e-08 33.9 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.11 001152695.1_53722001_3 - 1.4e-08 34.8 0.0 2.6e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.21 001152695.1_53722001_3 - 8e-08 32.2 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.8 001152695.1_53722001_3 - 1e-07 31.4 0.0 1.4e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.20 001152695.1_53722001_3 - 1.6e-06 27.7 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.10 001152695.1_53722001_3 - 0.0019 17.5 0.0 0.0025 17.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.7 001152695.1_53722001_3 - 0.011 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Acyltransferase PF01553.19 001147280.1_53723001_1 - 9.6e-07 28.4 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Inhibitor_I9 PF05922.14 001156736.1_53722001_3 - 0.02 15.4 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I9 PP2 PF14299.4 001156484.1_53723001_1 - 6.7e-39 133.1 0.1 9.3e-39 132.6 0.1 1.2 1 0 0 1 1 1 1 Phloem protein 2 F-box-like PF12937.5 001156484.1_53723001_1 - 0.05 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.31 001156484.1_53723001_1 - 0.074 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain PPR_2 PF13041.4 001147538.1_53724001_3 - 2.9e-140 456.3 18.3 4.1e-17 62.0 0.2 13.7 3 1 11 14 14 14 11 PPR repeat family PPR_1 PF12854.5 001147538.1_53724001_3 - 4.5e-130 422.9 25.4 6.9e-13 47.9 0.0 14.1 14 0 0 14 14 14 13 PPR repeat PPR PF01535.18 001147538.1_53724001_3 - 2.7e-89 287.3 19.8 7e-09 35.2 0.0 13.9 14 0 0 14 14 14 12 PPR repeat PPR_3 PF13812.4 001147538.1_53724001_3 - 3.8e-83 273.4 12.7 1.1e-13 50.9 0.0 8.9 1 1 8 10 10 10 10 Pentatricopeptide repeat domain PPR_long PF17177.2 001147538.1_53724001_3 - 4.9e-29 101.1 0.0 2.5e-13 49.8 0.0 4.7 2 1 4 6 6 6 5 Pentacotripeptide-repeat region of PROPR MRP-S27 PF10037.7 001147538.1_53724001_3 - 3.3e-10 39.3 0.0 0.018 13.8 0.0 4.1 1 1 3 4 4 4 3 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.4 001147538.1_53724001_3 - 3.8e-08 33.6 0.0 0.1 13.0 0.0 7.2 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_14 PF13428.4 001147538.1_53724001_3 - 4.5e-08 33.1 7.1 1.5 9.7 0.1 9.5 8 2 3 11 11 10 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.8 001147538.1_53724001_3 - 8.2e-06 25.3 0.1 0.83 9.2 0.0 4.4 3 2 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) ATP13 PF12921.5 001147538.1_53724001_3 - 1.5e-05 24.7 0.0 19 5.0 0.0 6.4 5 4 3 8 8 7 0 Mitochondrial ATPase expression ECSIT PF06239.9 001147538.1_53724001_3 - 3.8e-05 22.8 0.0 1.1 8.2 0.0 4.9 4 1 2 7 7 7 1 Evolutionarily conserved signalling intermediate in Toll pathway ANAPC3 PF12895.5 001147538.1_53724001_3 - 0.00012 22.0 0.8 2.8 8.1 0.0 6.0 4 2 4 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3368 PF11848.6 001147538.1_53724001_3 - 0.0038 16.9 0.1 63 3.4 0.0 6.0 8 0 0 8 8 7 0 Domain of unknown function (DUF3368) Clathrin PF00637.18 001147538.1_53724001_3 - 0.012 15.4 0.0 21 4.8 0.0 4.3 3 2 0 3 3 3 0 Region in Clathrin and VPS BKACE PF05853.10 001147538.1_53724001_3 - 0.021 14.0 0.0 8.6 5.4 0.0 3.1 1 1 1 3 3 3 0 beta-keto acid cleavage enzyme Glyco_trans_4_3 PF12000.6 001147538.1_53724001_3 - 0.053 13.1 0.0 36 3.9 0.0 3.8 2 2 2 4 4 4 0 Gkycosyl transferase family 4 group TSCPD PF12637.5 001147538.1_53724001_3 - 0.07 13.2 0.0 2.5 8.2 0.0 3.1 3 0 0 3 3 2 0 TSCPD domain SPOB_a PF14689.4 001147538.1_53724001_3 - 0.11 12.1 0.0 20 4.8 0.0 3.1 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain BTAD PF03704.15 001147538.1_53724001_3 - 0.12 12.7 4.1 15 5.9 0.4 3.8 4 1 0 4 4 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.12 001147538.1_53724001_3 - 2.1 9.1 15.9 2.5 8.9 0.1 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_16 PF13432.4 001147538.1_53724001_3 - 5.8 7.6 7.4 29 5.3 2.3 4.4 6 0 0 6 6 5 0 Tetratricopeptide repeat Ion_trans PF00520.29 001158016.1_53724001_1 - 9.9e-10 37.9 2.1 1.5e-09 37.4 2.1 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.27 001158016.1_53724001_1 - 2.5e-07 30.5 0.0 4.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain ADH_zinc_N PF00107.24 001147043.1_53724001_1 - 2.2e-24 85.7 0.0 3.8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001147043.1_53724001_1 - 9.7e-23 80.0 4.8 2e-22 79.0 4.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.17 001147043.1_53724001_1 - 0.0007 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.4 001147043.1_53724001_1 - 0.0034 18.3 0.0 0.0066 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.16 001147043.1_53724001_1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.19 001147043.1_53724001_1 - 0.019 14.1 0.1 0.031 13.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.12 001147043.1_53724001_1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CRAL_TRIO_2 PF13716.4 001152704.1_53724001_1 - 2.6e-25 89.0 0.0 3.7e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ribosomal_L38e PF01781.16 001153692.1_53722001_3 - 2.9e-35 120.0 1.2 4.2e-35 119.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family LIM PF00412.20 001154201.1_53723001_2 - 1.9e-20 72.7 18.7 3.5e-10 39.8 5.3 2.4 2 0 0 2 2 2 2 LIM domain zf-3CxxC_2 PF17180.2 001154201.1_53723001_2 - 2.4 8.8 17.6 0.44 11.2 0.4 3.9 2 2 1 3 3 3 0 Zinc-binding domain GASA PF02704.12 001153948.1_53722001_1 - 1.3e-15 57.2 26.5 1.3e-15 57.2 26.5 2.8 3 0 0 3 3 3 1 Gibberellin regulated protein DSPc PF00782.18 001158274.1_53723001_3 - 1.1e-22 80.2 0.0 1.8e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.10 001158274.1_53723001_3 - 0.022 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.25 001158274.1_53723001_3 - 0.035 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase APP_N PF02177.14 001158274.1_53723001_3 - 0.055 13.7 0.2 0.69 10.2 0.1 2.2 1 1 1 2 2 2 0 Amyloid A4 N-terminal heparin-binding Y_phosphatase2 PF03162.11 001158274.1_53723001_3 - 0.057 12.9 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family SCNM1_acidic PF15805.3 001158274.1_53723001_3 - 0.12 12.0 0.2 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 zf-HIT PF04438.14 001158274.1_53723001_3 - 1 9.1 4.2 8.1 6.3 0.7 2.5 2 0 0 2 2 2 0 HIT zinc finger zf-RRN7 PF11781.6 001158274.1_53723001_3 - 8.4 6.1 8.9 5.4 6.6 1.5 2.5 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 HLH PF00010.24 001159038.1_53723001_3 - 5.6e-05 22.9 0.1 5.6e-05 22.9 0.1 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain zf-TAZ PF02135.14 001153192.1_53724001_3 - 3.1e-11 43.4 6.4 7.3e-11 42.3 6.4 1.7 1 0 0 1 1 1 1 TAZ zinc finger BTB PF00651.29 001153192.1_53724001_3 - 3.7e-11 43.1 0.0 6.1e-10 39.2 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain FAD_binding_4 PF01565.21 001159040.1_53725001_3 - 3e-19 69.0 2.4 6.4e-19 67.9 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.12 001159040.1_53725001_3 - 3.7e-12 46.5 0.0 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Phospholip_A2_1 PF00068.17 001157256.1_53722001_3 - 7.2e-05 23.0 10.3 0.00012 22.3 10.3 1.4 1 0 0 1 1 1 1 Phospholipase A2 DUF296 PF03479.13 001157768.1_53724001_1 - 1.4e-27 96.0 1.0 2e-27 95.5 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF296) CytB6-F_Fe-S PF08802.8 001147793.1_53723001_1 - 2.4e-18 65.7 0.6 2.4e-18 65.7 0.6 1.8 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit Rieske PF00355.24 001147793.1_53723001_1 - 1.4e-12 47.3 0.2 2.8e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain WHAMM-JMY_N PF15920.3 001147793.1_53723001_1 - 0.071 12.8 0.4 0.12 12.1 0.4 1.3 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated DUF3239 PF11580.6 001149149.1_53722001_1 - 0.084 13.1 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) DUF4050 PF13259.4 001150833.1_53722001_2 - 7.4e-20 71.9 1.5 1.3e-13 51.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) Mito_fiss_Elm1 PF06258.9 001146815.1_53724001_1 - 2e-121 404.7 0.0 2.5e-121 404.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission ELM1 Allene_ox_cyc PF06351.9 001147795.1_53723001_2 - 7.8e-94 312.0 0.0 9.8e-94 311.6 0.0 1.1 1 0 0 1 1 1 1 Allene oxide cyclase Dirigent PF03018.12 001147795.1_53723001_2 - 0.00044 20.1 0.0 0.00077 19.3 0.0 1.4 1 1 0 1 1 1 1 Dirigent-like protein Phosphoesterase PF04185.12 001152958.1_53724001_3 - 1.5e-102 343.3 0.0 1.8e-102 343.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family DHquinase_I PF01487.13 001146817.1_53725001_1 - 7.4e-45 153.8 0.0 1.2e-44 153.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.9 001146817.1_53725001_1 - 9.6e-24 83.3 0.0 2e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.18 001146817.1_53725001_1 - 1.1e-08 35.2 0.1 2.4e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.15 001146817.1_53725001_1 - 0.00019 21.8 0.1 0.00044 20.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.22 001146817.1_53725001_1 - 0.00034 19.7 0.8 0.00052 19.1 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.16 001146817.1_53725001_1 - 0.0033 17.5 0.6 0.036 14.2 0.1 2.5 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain AdoHcyase_NAD PF00670.19 001146817.1_53725001_1 - 0.015 15.3 0.2 0.034 14.1 0.2 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.19 001146817.1_53725001_1 - 0.022 13.9 0.1 0.037 13.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HpaB_N PF11794.6 001146817.1_53725001_1 - 0.023 14.2 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Pyr_redox_2 PF07992.12 001146817.1_53725001_1 - 0.026 13.7 0.1 0.038 13.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.23 001146817.1_53725001_1 - 0.08 12.3 2.8 0.23 10.8 0.8 2.1 2 0 0 2 2 2 0 short chain dehydrogenase IlvN PF07991.10 001146817.1_53725001_1 - 0.088 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.13 001146817.1_53725001_1 - 0.14 12.2 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.20 001146817.1_53725001_1 - 0.31 9.9 1.4 0.56 9.1 1.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Aminotran_1_2 PF00155.19 001155481.1_53725001_2 - 5.5e-55 186.9 0.0 6.6e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.17 001155481.1_53725001_2 - 0.00084 18.3 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.19 001155481.1_53725001_2 - 0.0057 15.8 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.15 001155481.1_53725001_2 - 0.031 13.4 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Mago-bind PF09282.8 001147797.1_53723001_1 - 1.2e-14 53.7 3.7 2.8e-14 52.5 3.7 1.7 1 0 0 1 1 1 1 Mago binding Med9 PF07544.11 001147797.1_53723001_1 - 0.037 14.0 1.7 0.072 13.1 1.1 1.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Mo25 PF08569.9 001156243.1_53723001_1 - 7.5e-52 176.6 7.2 7.5e-52 176.6 7.2 1.3 2 0 0 2 2 2 1 Mo25-like HEAT PF02985.20 001156243.1_53723001_1 - 0.077 13.1 0.0 5.2 7.4 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat DUF4604 PF15377.4 001156243.1_53723001_1 - 0.14 12.4 19.6 0.05 13.9 16.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Mo25 PF08569.9 001156243.1_53723001_3 - 1.1e-48 166.2 0.0 1.1e-48 166.2 0.0 1.5 2 0 0 2 2 2 1 Mo25-like DUF788 PF05620.9 001156243.1_53723001_3 - 0.018 14.8 7.5 0.031 14.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Zip PF02535.20 001156243.1_53723001_3 - 0.041 13.0 1.0 0.055 12.5 1.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.17 001156243.1_53723001_3 - 0.16 11.6 7.2 0.26 10.9 7.2 1.3 1 0 0 1 1 1 0 Connexin 7tm_1 PF00001.19 001156243.1_53723001_3 - 0.57 9.2 4.7 0.88 8.6 4.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) EphA2_TM PF14575.4 001156243.1_53723001_3 - 4 8.2 4.7 8.7 7.1 4.7 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3899 PF13038.4 001156243.1_53723001_3 - 6 7.3 10.7 15 6.0 10.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) NTP_transferase PF00483.21 001148743.1_53724001_2 - 5.6e-52 176.6 0.0 7.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001148743.1_53724001_2 - 3.2e-11 43.7 0.0 5.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001148743.1_53724001_2 - 9.5e-08 31.3 8.2 3.3e-07 29.6 0.9 3.9 4 0 0 4 4 4 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.4 001148743.1_53724001_2 - 0.0048 16.5 5.8 0.021 14.5 4.1 2.9 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.17 001148743.1_53724001_2 - 0.017 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase DUF257 PF03192.11 001148743.1_53724001_2 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 DUF647 PF04884.12 001152963.1_53724001_3 - 6.6e-66 222.2 0.1 8.9e-66 221.8 0.1 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis JAB PF01398.19 001147304.1_53724001_2 - 4.4e-13 49.1 0.0 1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pkinase PF00069.23 001153450.1_53725001_1 - 8.4e-68 228.4 0.0 1.1e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001153450.1_53725001_1 - 1.3e-33 116.3 0.0 1.8e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001153450.1_53725001_1 - 4.8e-06 26.0 0.2 2.5e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001153450.1_53725001_1 - 1.3e-05 24.5 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001153450.1_53725001_1 - 0.00043 20.1 0.0 0.047 13.5 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.4 001158796.1_53723001_1 - 4.4e-09 35.9 4.5 6.6e-09 35.4 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001158796.1_53723001_1 - 9.2e-09 34.9 10.6 1.8e-08 34.0 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001158796.1_53723001_1 - 1.6e-08 34.1 8.3 2.9e-08 33.3 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001158796.1_53723001_1 - 6e-08 32.7 11.2 1.1e-07 31.9 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.4 001158796.1_53723001_1 - 5.4e-07 29.4 8.4 5.6e-07 29.3 5.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 001158796.1_53723001_1 - 9.9e-07 28.5 7.3 1.5e-06 27.9 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.4 001158796.1_53723001_1 - 1.9e-06 27.8 9.7 3.1e-06 27.1 9.7 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.4 001158796.1_53723001_1 - 8.8e-05 22.1 7.9 0.00015 21.4 7.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.5 001158796.1_53723001_1 - 0.00088 19.2 2.5 0.0018 18.2 2.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.5 001158796.1_53723001_1 - 0.024 14.8 8.8 0.059 13.5 8.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.9 001158796.1_53723001_1 - 0.11 12.3 2.9 0.16 11.8 2.9 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.4 001158796.1_53723001_1 - 0.16 11.7 3.1 0.34 10.7 3.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.3 001158796.1_53723001_1 - 1.4 9.0 5.3 2.7 8.0 5.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.19 001158796.1_53723001_1 - 7.9 6.7 9.2 7.2 6.8 7.6 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain tify PF06200.12 001147557.1_53724001_2 - 3.7e-18 64.4 0.0 7.8e-18 63.4 0.0 1.6 1 0 0 1 1 1 1 tify domain CCT_2 PF09425.8 001147557.1_53724001_2 - 6.1e-14 51.5 2.9 1.4e-13 50.3 2.9 1.7 1 0 0 1 1 1 1 Divergent CCT motif Plus-3 PF03126.16 001152275.1_53725001_3 - 4.8e-29 100.9 0.0 8.4e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Plus-3 domain Cu_bind_like PF02298.15 001147807.1_53723001_1 - 9.8e-22 76.6 0.0 1.7e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Plastocyanin-like domain Prefoldin PF02996.15 001157528.1_53722001_2 - 2.6e-29 101.4 0.5 3.4e-29 101.1 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit ABC2_membrane PF01061.22 001158039.1_53725001_1 - 1.6e-36 125.6 12.3 2.3e-36 125.1 12.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.25 001158039.1_53725001_1 - 8.2e-28 97.5 0.0 1.4e-26 93.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.5 001158039.1_53725001_1 - 1.2e-05 24.4 9.3 1.7e-05 24.0 9.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.4 001158039.1_53725001_1 - 0.00014 21.7 3.6 0.13 11.9 0.4 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.4 001158039.1_53725001_1 - 0.00058 20.2 0.9 0.00079 19.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.4 001158039.1_53725001_1 - 0.0068 16.6 0.6 0.053 13.7 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.4 001158039.1_53725001_1 - 0.0083 15.7 1.4 0.032 13.8 0.4 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.15 001158039.1_53725001_1 - 0.019 14.6 0.1 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein SMC_N PF02463.17 001158039.1_53725001_1 - 0.024 13.9 0.2 1 8.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.14 001158039.1_53725001_1 - 0.046 13.5 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.4 001158039.1_53725001_1 - 0.08 13.3 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.13 001158039.1_53725001_1 - 0.091 11.5 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein T2SSE PF00437.18 001158039.1_53725001_1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.4 001158039.1_53725001_1 - 0.15 11.5 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.15 001158039.1_53725001_1 - 0.2 11.5 0.3 0.47 10.3 0.3 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.4 001158039.1_53725001_1 - 0.34 10.5 0.6 0.72 9.4 0.6 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.5 001158039.1_53725001_1 - 1.6 7.8 6.8 2.7 7.0 6.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_33 PF13671.4 001158039.1_53725001_1 - 5.6 7.0 5.4 1.2 9.1 1.0 2.1 2 1 0 3 3 3 0 AAA domain Abhydrolase_6 PF12697.5 001154225.1_53723001_3 - 2.3e-20 74.0 1.0 2.3e-20 74.0 1.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001154225.1_53723001_3 - 1.5e-17 64.0 0.2 2.1e-15 57.0 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001154225.1_53723001_3 - 4.4e-13 48.9 0.0 3.1e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.11 001154225.1_53723001_3 - 0.011 15.5 0.0 0.031 14.0 0.1 1.7 1 1 0 1 1 1 0 Serine hydrolase Vps26 PF03643.13 001155244.1_53723001_2 - 8.7e-123 408.5 2.0 1e-122 408.3 2.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.27 001155244.1_53723001_2 - 0.0027 17.6 0.3 3.1 7.7 0.1 3.2 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain VID27 PF08553.8 001158805.1_53725001_3 - 1.4e-47 162.7 0.0 2.7e-47 161.7 0.0 1.3 1 1 0 1 1 1 1 VID27 cytoplasmic protein WD40 PF00400.30 001158805.1_53725001_3 - 0.0052 17.5 2.2 1.3 9.8 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ComA PF02679.13 001156259.1_53723001_1 - 4.7e-78 261.9 0.0 6.3e-78 261.4 0.0 1.1 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) AP_endonuc_2 PF01261.22 001156259.1_53723001_1 - 0.018 14.3 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PEP_mutase PF13714.4 001156259.1_53723001_1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase LAS2 PF15792.3 001156259.1_53723001_1 - 0.16 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Lung adenoma susceptibility protein 2 DUF1168 PF06658.10 001156517.1_53723001_3 - 1.3e-27 96.1 21.6 1.3e-27 96.1 21.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Axin_b-cat_bind PF08833.8 001147072.1_53723001_2 - 0.3 11.1 2.3 1.1 9.3 0.0 3.0 2 0 0 2 2 2 0 Axin beta-catenin binding domain FMO-like PF00743.17 001154489.1_53724001_2 - 6.2e-31 107.3 0.0 9.4e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 001154489.1_53724001_2 - 1.2e-24 87.0 0.0 5.3e-22 78.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 001154489.1_53724001_2 - 1.1e-17 64.1 0.0 4.4e-13 49.0 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 001154489.1_53724001_2 - 5e-16 58.7 0.0 8.4e-12 44.8 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001154489.1_53724001_2 - 3e-07 29.9 0.2 0.00019 20.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.4 001154489.1_53724001_2 - 7.7e-06 25.9 5.6 0.033 14.1 0.0 4.1 3 1 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.4 001154489.1_53724001_2 - 3.7e-05 23.8 0.0 0.00016 21.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.25 001154489.1_53724001_2 - 4.5e-05 23.8 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001154489.1_53724001_2 - 0.004 16.7 1.9 0.064 12.7 0.1 3.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase ApbA PF02558.14 001154489.1_53724001_2 - 0.0091 15.5 0.0 4.7 6.7 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Thi4 PF01946.15 001154489.1_53724001_2 - 0.01 14.9 0.2 0.29 10.2 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.22 001154489.1_53724001_2 - 0.014 14.4 1.0 0.56 9.1 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.20 001154489.1_53724001_2 - 0.02 13.8 0.0 7.5 5.4 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.10 001154489.1_53724001_2 - 0.083 11.8 1.4 2.6 6.9 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.12 001154489.1_53724001_2 - 0.11 11.0 0.8 1.4 7.4 0.2 2.6 3 0 0 3 3 3 0 HI0933-like protein p450 PF00067.20 001152977.1_53724001_1 - 9.1e-07 27.8 0.0 1.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001152977.1_53724001_2 - 1.2e-71 241.7 0.0 1.5e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KIP1 PF07765.10 001148283.1_53726001_2 - 5.6e-37 125.6 5.3 5.6e-37 125.6 5.3 2.1 2 0 0 2 2 2 1 KIP1-like protein CENP-F_leu_zip PF10473.7 001148283.1_53726001_2 - 0.0021 18.0 12.4 0.0021 18.0 12.4 3.2 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.8 001148283.1_53726001_2 - 0.0034 17.4 17.0 0.05 13.6 4.5 3.2 3 0 0 3 3 3 2 Fibrinogen alpha/beta chain family Gp58 PF07902.9 001148283.1_53726001_2 - 0.041 12.2 2.7 0.064 11.5 2.7 1.3 1 0 0 1 1 1 0 gp58-like protein CALCOCO1 PF07888.9 001148283.1_53726001_2 - 0.044 12.2 27.6 0.0038 15.7 22.8 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1041 PF06292.15 001148283.1_53726001_2 - 0.05 13.8 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) MAD PF05557.11 001148283.1_53726001_2 - 0.1 10.8 31.1 0.022 13.0 26.3 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF4407 PF14362.4 001148283.1_53726001_2 - 0.59 9.3 22.4 0.071 12.3 13.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HMMR_N PF15905.3 001148283.1_53726001_2 - 0.89 8.8 32.4 0.2 10.9 16.3 2.8 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal ALMT PF11744.6 001148283.1_53726001_2 - 1.3 7.7 8.0 2.5 6.7 8.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter GAS PF13851.4 001148283.1_53726001_2 - 1.7 7.9 32.9 0.27 10.4 16.5 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding MbeD_MobD PF04899.10 001148283.1_53726001_2 - 3.5 7.7 6.0 32 4.6 2.3 3.5 2 1 1 3 3 3 0 MbeD/MobD like DUF2205 PF10224.7 001148283.1_53726001_2 - 5.3 7.0 19.4 2.7 7.9 3.4 4.2 5 0 0 5 5 5 0 Predicted coiled-coil protein (DUF2205) Tropomyosin PF00261.18 001148283.1_53726001_2 - 5.8 6.1 43.9 5.7 6.1 10.8 3.3 2 1 1 3 3 3 0 Tropomyosin DUF1664 PF07889.10 001148283.1_53726001_2 - 6.9 6.5 14.3 12 5.7 2.6 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.10 001148283.1_53726001_2 - 9.1 6.2 36.6 1.8 8.5 9.9 3.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Glyco_hydro_19 PF00182.17 001157282.1_53723001_2 - 1.8e-49 168.5 23.6 1.5e-42 145.9 7.2 3.2 2 1 1 3 3 3 2 Chitinase class I Chitin_bind_1 PF00187.17 001157282.1_53723001_2 - 2.7e-08 34.0 20.7 2.7e-08 34.0 20.7 2.9 3 0 0 3 3 3 1 Chitin recognition protein TarH PF02203.13 001151225.1_53724001_2 - 0.096 12.5 0.3 0.096 12.5 0.3 1.5 2 0 0 2 2 2 0 Tar ligand binding domain homologue HrpB2 PF09487.8 001151225.1_53724001_2 - 0.46 10.8 2.7 4 7.8 1.4 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) LRRFIP PF09738.7 001151225.1_53724001_2 - 0.5 9.7 6.8 0.76 9.1 6.8 1.2 1 0 0 1 1 1 0 LRRFIP family Occludin_ELL PF07303.11 001151225.1_53724001_2 - 0.66 10.6 3.7 5.7 7.6 0.1 2.6 3 0 0 3 3 3 0 Occludin homology domain TSP9 PF11493.6 001151583.1_53722001_2 - 1.8e-17 63.7 5.2 1.8e-17 63.7 5.2 2.4 2 1 1 3 3 3 1 Thylakoid soluble phosphoprotein TSP9 DSS1_SEM1 PF05160.11 001153724.1_53722001_2 - 5.3e-17 61.5 25.7 7.1e-17 61.1 25.7 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Alg14 PF08660.9 001148527.1_53724001_2 - 1.5e-17 64.0 0.3 3.3e-17 62.8 0.0 1.6 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like Alg14 PF08660.9 001148527.1_53724001_3 - 1.4e-42 145.4 2.9 1.2e-41 142.4 0.2 2.2 2 0 0 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like FAD_binding_3 PF01494.17 001158052.1_53724001_1 - 1.1e-20 74.1 3.2 1.6e-09 37.4 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.22 001158052.1_53724001_1 - 9.1e-05 22.1 1.8 0.00019 21.1 1.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.4 001158052.1_53724001_1 - 0.00095 19.2 3.2 0.0012 18.9 1.8 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.12 001158052.1_53724001_1 - 0.095 11.8 3.2 0.17 11.0 3.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.5 001158052.1_53724001_1 - 0.099 11.8 1.8 0.13 11.4 1.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.22 001158052.1_53724001_1 - 0.11 11.5 9.7 0.21 10.5 9.7 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.15 001158052.1_53724001_1 - 0.12 11.4 5.1 0.19 10.8 5.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.4 001158052.1_53724001_1 - 0.17 11.0 1.9 0.27 10.3 1.9 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001158052.1_53724001_1 - 0.69 8.4 6.1 1 7.8 6.1 1.2 1 0 0 1 1 1 0 HI0933-like protein HSP20 PF00011.19 001152981.1_53723001_1 - 1.5e-06 28.2 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family FA_hydroxylase PF04116.11 001155761.1_53723001_1 - 6.4e-20 71.7 25.7 1.7e-19 70.3 23.5 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2365 PF10157.7 001150857.1_53722001_1 - 7.9e-05 22.8 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DUF2397 PF09660.8 001150857.1_53722001_1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) TMEM171 PF15471.4 001150857.1_53722001_1 - 7.7 5.3 7.1 11 4.7 7.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Pkinase_Tyr PF07714.15 001152295.1_53725001_1 - 4.2e-46 157.2 0.0 8.1e-46 156.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001152295.1_53725001_1 - 1.2e-43 149.3 0.0 1.6e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1191 PF06697.10 001152295.1_53725001_1 - 0.041 13.0 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) APH PF01636.21 001152295.1_53725001_1 - 0.091 12.5 0.0 0.26 11.0 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Herpes_gE PF02480.14 001152295.1_53725001_1 - 0.11 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.4 001152295.1_53725001_1 - 0.11 13.1 0.0 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.13 001152295.1_53725001_1 - 0.16 11.6 0.7 0.29 10.8 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Stress-antifung PF01657.15 001154755.1_53724001_2 - 1.9e-30 105.2 14.6 5.3e-20 71.7 0.9 2.9 3 0 0 3 3 3 2 Salt stress response/antifungal MtrG PF04210.11 001154755.1_53724001_2 - 0.046 13.4 0.4 0.076 12.7 0.4 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Adeno_E3_CR2 PF02439.13 001154755.1_53724001_2 - 0.11 12.1 1.8 0.33 10.6 1.8 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cupin_8 PF13621.4 001147084.1_53724001_3 - 1.4e-49 169.1 0.0 2e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.10 001147084.1_53724001_3 - 2.3e-12 46.9 0.1 3.6e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.20 001147084.1_53724001_3 - 7.5e-05 23.0 0.3 0.00041 20.6 0.0 2.3 2 2 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.9 001147084.1_53724001_3 - 0.0089 15.6 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Cupin domain tRNA_int_endo PF01974.15 001155514.1_53723001_3 - 4e-21 74.7 0.0 6.8e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.12 001155514.1_53723001_3 - 0.00054 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain DnaJ PF00226.29 001157295.1_53723001_1 - 4.8e-26 90.5 0.5 1.3e-25 89.2 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain Nefa_Nip30_N PF10187.7 001157295.1_53723001_1 - 0.052 13.8 0.1 0.052 13.8 0.1 3.0 2 2 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3323 PF11796.6 001157295.1_53723001_1 - 0.075 12.8 0.1 6.8 6.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DUF1497 PF07384.9 001157295.1_53723001_1 - 0.077 13.3 0.4 0.2 11.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) TipAS PF07739.11 001157295.1_53723001_1 - 7 7.1 7.5 1 9.8 0.6 2.8 2 2 1 3 3 3 0 TipAS antibiotic-recognition domain Memo PF01875.15 001147584.1_53723001_3 - 2.8e-80 269.2 0.0 3.4e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Myb_DNA-binding PF00249.29 001147830.1_53723001_3 - 1.9e-32 111.0 1.6 1.1e-16 60.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001147830.1_53723001_3 - 5.8e-20 71.2 0.0 1.5e-10 41.0 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF1681 PF07933.12 001147335.1_53723001_1 - 4.5e-50 169.1 0.0 5.9e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CENP-F_leu_zip PF10473.7 001149175.1_53723001_1 - 0.048 13.5 2.5 0.07 13.0 2.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PTCB-BRCT PF12738.5 001155521.1_53724001_2 - 1.1e-21 76.4 0.5 2.1e-21 75.5 0.5 1.5 1 0 0 1 1 1 1 twin BRCT domain zf-RING_2 PF13639.4 001155521.1_53724001_2 - 4.7e-09 36.2 9.7 4.7e-09 36.2 9.7 3.3 3 0 0 3 3 2 1 Ring finger domain BRCT PF00533.24 001155521.1_53724001_2 - 3.5e-08 33.6 0.0 7.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4 PF00097.23 001155521.1_53724001_2 - 7.7e-08 32.0 6.3 7.7e-08 32.0 6.3 3.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001155521.1_53724001_2 - 2.5e-05 24.1 3.9 2.5e-05 24.1 3.9 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.4 001155521.1_53724001_2 - 3.6e-05 23.4 7.6 3.6e-05 23.4 7.6 3.0 3 2 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001155521.1_53724001_2 - 7.7e-05 22.4 6.9 7.7e-05 22.4 6.9 3.2 3 1 0 3 3 2 1 zinc-RING finger domain BRCT_2 PF16589.3 001155521.1_53724001_2 - 0.00015 22.0 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Prok-RING_4 PF14447.4 001155521.1_53724001_2 - 0.00092 18.9 10.5 0.00092 18.9 10.5 3.0 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 PHD PF00628.27 001155521.1_53724001_2 - 0.0022 17.7 10.2 0.0022 17.7 10.2 3.0 3 1 0 3 3 2 1 PHD-finger zf-C3HC4_4 PF15227.4 001155521.1_53724001_2 - 0.0072 16.3 7.9 0.0072 16.3 7.9 3.4 3 2 1 4 4 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.3 001155521.1_53724001_2 - 0.014 15.0 4.1 0.014 15.0 4.1 2.5 2 0 0 2 2 1 0 RING-like zinc finger zf-rbx1 PF12678.5 001155521.1_53724001_2 - 0.015 15.5 6.8 0.015 15.5 6.8 3.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain MatE PF01554.16 001153236.1_53724001_2 - 1.2e-48 164.7 34.6 9.5e-26 90.2 8.6 3.1 2 1 0 3 3 3 2 MatE RRM_1 PF00076.20 001155015.1_53724001_2 - 1.1e-49 166.0 0.0 2.1e-18 65.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001155015.1_53724001_2 - 0.00052 19.5 0.0 0.06 12.8 0.0 2.9 2 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001155015.1_53724001_2 - 0.00053 19.9 0.0 2.3 8.3 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.3 001155015.1_53724001_2 - 0.00075 19.2 0.0 2.5 7.9 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.8 001155015.1_53724001_2 - 0.026 14.5 0.1 11 6.1 0.0 3.2 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) PHM7_cyt PF14703.4 001155015.1_53724001_2 - 0.26 11.4 4.6 1.5 8.9 0.0 3.4 4 0 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DUF4005 PF13178.4 001148303.1_53725001_2 - 3.5e-13 49.9 6.3 3.5e-13 49.9 6.3 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4005) IQ PF00612.25 001148303.1_53725001_2 - 1.2e-09 36.9 11.9 0.00045 19.6 1.3 3.6 3 0 0 3 3 3 3 IQ calmodulin-binding motif Diphthamide_syn PF01866.15 001157558.1_53724001_1 - 1.8e-96 323.0 0.0 2.3e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF4653 PF15546.4 001157558.1_53724001_1 - 0.099 12.1 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) OGG_N PF07934.10 001148304.1_53724001_1 - 1.1e-17 64.1 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.23 001148304.1_53724001_1 - 1.4e-13 51.1 0.0 2.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.21 001148304.1_53724001_1 - 0.00018 21.1 0.0 0.00042 19.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.5 001148304.1_53724001_1 - 0.042 13.8 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Glyco_transf_8 PF01501.18 001148783.1_53724001_3 - 7.5e-47 159.9 0.0 9.2e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_C97 PF05903.12 001150446.1_53723001_1 - 6.3e-40 136.3 0.0 8.8e-40 135.9 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain WW PF00397.24 001151240.1_53723001_2 - 4.5e-06 26.4 0.4 4.5e-06 26.4 0.4 1.9 2 0 0 2 2 2 1 WW domain Spt4 PF06093.11 001151240.1_53723001_2 - 0.094 12.7 1.7 0.18 11.8 1.7 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger CAP_N PF01213.17 001151240.1_53723001_3 - 4.6 6.5 7.3 9.9 5.4 7.3 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PHD_Oberon PF07227.9 001152996.1_53725001_3 - 3.5e-31 107.6 22.1 8.7e-31 106.3 22.1 1.7 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein fn3 PF00041.19 001152996.1_53725001_3 - 2.2e-06 27.8 0.0 4.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain PGI PF00342.17 001154511.1_53725001_3 - 1.9e-60 204.7 0.0 8.8e-49 166.3 0.0 2.1 2 0 0 2 2 2 2 Phosphoglucose isomerase Cullin_binding PF03556.13 001155524.1_53723001_3 - 7.3e-23 81.2 0.4 1.3e-22 80.4 0.4 1.4 1 0 0 1 1 1 1 Cullin binding Methyltransf_2 PF00891.16 001147095.1_53723001_2 - 1.9e-58 197.2 0.0 2.7e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.9 001147095.1_53723001_2 - 1.4e-08 34.5 0.0 2.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.4 001147095.1_53723001_2 - 0.0016 18.2 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001147095.1_53723001_2 - 0.014 16.0 0.1 0.086 13.4 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.4 001147095.1_53723001_2 - 0.069 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UDPGT PF00201.16 001148785.1_53722001_2 - 5.6e-18 64.9 0.3 6.9e-18 64.6 0.3 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_4 PF13692.4 001148785.1_53722001_2 - 0.039 14.3 0.2 0.077 13.3 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 GDA1_CD39 PF01150.15 001154513.1_53725001_3 - 1.3e-83 280.9 0.0 1.8e-83 280.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PPR PF01535.18 001152545.1_53724001_2 - 7.7e-72 232.6 5.2 4.7e-08 32.6 0.0 12.3 12 0 0 12 12 12 11 PPR repeat PPR_2 PF13041.4 001152545.1_53724001_2 - 1.4e-60 201.2 2.3 1.9e-11 43.8 0.0 10.3 4 2 7 11 11 11 9 PPR repeat family PPR_1 PF12854.5 001152545.1_53724001_2 - 9.5e-53 175.5 0.0 2.1e-09 36.8 0.0 10.2 10 0 0 10 10 10 8 PPR repeat PPR_3 PF13812.4 001152545.1_53724001_2 - 1.9e-21 75.8 0.0 8.6e-06 25.6 0.0 6.8 3 2 3 7 7 7 5 Pentatricopeptide repeat domain TPR_19 PF14559.4 001152545.1_53724001_2 - 8.6e-12 45.3 7.8 0.066 13.6 0.1 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat PPR_long PF17177.2 001152545.1_53724001_2 - 2.2e-11 43.4 0.0 0.0005 19.4 0.0 4.2 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001152545.1_53724001_2 - 9e-11 41.5 14.7 4 8.4 0.0 9.8 5 3 5 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.4 001152545.1_53724001_2 - 3.4e-06 26.6 0.3 17 5.6 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.15 001152545.1_53724001_2 - 0.00068 19.4 13.1 24 5.3 0.1 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.4 001152545.1_53724001_2 - 0.014 15.9 21.2 1.4 9.5 1.8 7.7 7 3 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.12 001152545.1_53724001_2 - 0.052 14.1 20.2 2.5 8.8 0.4 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3368 PF11848.6 001152545.1_53724001_2 - 0.071 12.8 0.0 78 3.0 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3368) Nup84_Nup100 PF04121.11 001152545.1_53724001_2 - 0.17 9.9 0.0 1.8 6.5 0.0 2.1 1 1 1 2 2 2 0 Nuclear pore protein 84 / 107 RIX1 PF08167.10 001150870.1_53724001_2 - 0.038 13.6 2.5 0.82 9.3 0.2 2.3 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HRM PF02793.20 001150870.1_53724001_2 - 0.18 12.0 1.4 0.34 11.1 1.4 1.5 1 0 0 1 1 1 0 Hormone receptor domain BTB PF00651.29 001148790.1_53725001_1 - 7.7e-15 54.9 0.2 1.7e-14 53.9 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.13 001148790.1_53725001_1 - 1.5e-09 37.7 0.9 3.9e-09 36.4 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch bHLH-MYC_N PF14215.4 001152548.1_53724001_1 - 3.2e-29 102.2 0.0 7.4e-27 94.5 0.0 2.2 1 1 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal NUDIX_2 PF13869.4 001165651.1_53723001_1 - 2.8e-68 229.1 0.0 3.5e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase SCAMP PF04144.11 001165524.1_53723001_2 - 2.8e-54 183.9 13.8 4.2e-54 183.3 13.8 1.3 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.6 001165524.1_53723001_2 - 0.2 10.9 6.7 0.31 10.3 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.12 001165524.1_53723001_2 - 0.34 10.8 2.5 0.57 10.0 2.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) efThoc1 PF11957.6 001165696.1_53725001_1 - 4.5e-98 328.9 0.2 9.2e-98 327.9 0.2 1.5 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor RINGv PF12906.5 001165698.1_53725001_1 - 1.2e-11 44.4 7.1 2e-11 43.7 7.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.4 001165698.1_53725001_1 - 0.013 15.6 4.1 0.026 14.7 4.1 1.5 1 0 0 1 1 1 0 Ring finger domain UPF0093 PF03653.11 001165698.1_53725001_1 - 0.18 11.9 2.5 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) CBFD_NFYB_HMF PF00808.21 001165544.1_53723001_1 - 7e-19 67.8 0.0 1.1e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001165544.1_53723001_1 - 0.0044 17.3 0.2 0.0044 17.3 0.2 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PhoLip_ATPase_C PF16212.3 001165713.1_53723001_3 - 1.2e-72 244.6 31.5 1.5e-72 244.2 31.5 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.10 001165713.1_53723001_3 - 0.00019 21.1 0.3 0.00028 20.6 0.3 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.24 001165713.1_53723001_3 - 0.2 11.8 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Arm PF00514.21 001165738.1_53722001_3 - 1.3e-11 44.0 0.8 1.6e-05 24.6 0.1 3.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Neurochondrin PF05536.9 001165738.1_53722001_3 - 4.3e-05 22.0 0.0 5.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Neurochondrin Phe_tRNA-synt_N PF02912.16 001165430.1_53723001_1 - 0.094 12.5 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain RRM_1 PF00076.20 001165430.1_53723001_3 - 2.1e-20 72.2 0.0 3.7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC144C PF14915.4 001165430.1_53723001_3 - 0.0086 15.1 8.3 0.015 14.3 8.3 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Swi5 PF07061.9 001165430.1_53723001_3 - 0.0097 15.8 1.9 0.0097 15.8 1.9 1.9 2 0 0 2 2 2 1 Swi5 TACC PF05010.12 001165430.1_53723001_3 - 0.011 15.3 8.8 0.93 9.1 8.8 2.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) RRM_7 PF16367.3 001165430.1_53723001_3 - 0.013 15.5 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Tropomyosin_1 PF12718.5 001165430.1_53723001_3 - 0.013 15.4 8.2 0.03 14.3 8.2 1.6 1 0 0 1 1 1 0 Tropomyosin like MAD PF05557.11 001165430.1_53723001_3 - 0.046 11.9 12.9 0.059 11.6 12.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Lebercilin PF15619.4 001165430.1_53723001_3 - 0.047 13.2 14.2 0.13 11.8 14.2 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.8 001165430.1_53723001_3 - 0.085 12.9 6.6 0.068 13.2 3.8 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.12 001165430.1_53723001_3 - 0.32 10.7 5.9 0.52 10.0 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GAS PF13851.4 001165430.1_53723001_3 - 0.35 10.1 15.5 0.02 14.2 10.4 1.5 2 0 0 2 2 1 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.4 001165430.1_53723001_3 - 0.46 10.7 4.4 0.39 10.9 1.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FlaC_arch PF05377.9 001165430.1_53723001_3 - 0.53 10.6 2.1 0.8 10.0 0.9 1.9 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) DivIVA PF05103.11 001165430.1_53723001_3 - 0.53 10.2 9.2 0.23 11.4 4.8 2.0 1 1 1 2 2 2 0 DivIVA protein Herpes_UL6 PF01763.14 001165430.1_53723001_3 - 0.62 8.4 4.3 0.85 7.9 4.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like HAUS5 PF14817.4 001165430.1_53723001_3 - 1.2 7.6 10.3 0.42 9.0 3.6 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 IncA PF04156.12 001165430.1_53723001_3 - 1.4 8.5 8.9 2.2 7.9 8.9 1.2 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.10 001165430.1_53723001_3 - 1.5 8.7 5.4 1 9.2 3.2 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.12 001165430.1_53723001_3 - 1.7 8.5 9.5 2.6 7.9 9.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Alanine_zipper PF11839.6 001165430.1_53723001_3 - 2.4 8.3 6.2 1.2 9.3 1.6 2.1 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein ABC_tran_CTD PF16326.3 001165430.1_53723001_3 - 2.7 8.2 8.6 17 5.6 4.2 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain APG6 PF04111.10 001165430.1_53723001_3 - 3.8 6.7 9.9 5.2 6.2 9.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FAM76 PF16046.3 001165430.1_53723001_3 - 3.9 6.6 12.0 5.6 6.1 12.0 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4094 PF13334.4 001165430.1_53723001_3 - 4.7 7.5 9.2 5.2 7.4 6.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DivIC PF04977.13 001165430.1_53723001_3 - 6.7 6.4 9.8 1.7 8.3 5.1 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.4 001165430.1_53723001_3 - 7.8 5.6 7.0 12 5.0 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myb_DNA-binding PF00249.29 001165572.1_53723001_1 - 5.1e-35 119.3 3.4 2.4e-18 65.9 0.2 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001165572.1_53723001_1 - 1.2e-23 83.0 0.0 1.1e-16 60.7 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Serglycin PF04360.10 001165572.1_53723001_1 - 3.1e-06 27.1 2.6 5.6e-06 26.2 2.6 1.3 1 0 0 1 1 1 1 Serglycin Myb_DNA-bind_2 PF08914.9 001165572.1_53723001_1 - 0.0067 16.4 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 2 Rap1 Myb domain SLIDE PF09111.8 001165572.1_53723001_1 - 0.0073 16.2 0.0 2.2 8.2 0.0 2.6 2 1 0 3 3 3 2 SLIDE LRR_6 PF13516.4 001165771.1_53725001_2 - 9.6e-22 75.0 35.2 0.32 11.0 0.1 16.2 17 0 0 17 17 17 9 Leucine Rich repeat LRR_4 PF12799.5 001165771.1_53725001_2 - 2.5e-11 43.4 5.9 0.16 12.3 0.3 10.1 8 2 3 12 12 12 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001165771.1_53725001_2 - 2.6e-05 23.8 4.1 0.25 11.0 0.1 6.5 8 0 0 8 8 8 1 Leucine rich repeat PQQ_3 PF13570.4 001165771.1_53725001_2 - 0.11 12.9 0.0 23 5.5 0.0 3.1 1 1 1 2 2 2 0 PQQ-like domain PPR_2 PF13041.4 001165804.1_53724001_3 - 2.5e-77 254.8 15.3 4.4e-16 58.7 0.0 10.3 4 2 7 11 11 11 9 PPR repeat family PPR_1 PF12854.5 001165804.1_53724001_3 - 2.2e-49 164.7 10.0 5.8e-11 41.8 0.0 10.7 12 1 0 12 12 12 6 PPR repeat PPR_3 PF13812.4 001165804.1_53724001_3 - 3.1e-48 161.6 1.0 3e-12 46.3 0.0 6.9 3 1 4 7 7 7 6 Pentatricopeptide repeat domain PPR PF01535.18 001165804.1_53724001_3 - 2e-47 156.0 12.8 4.4e-07 29.6 0.0 11.8 11 1 0 11 11 11 9 PPR repeat PPR_long PF17177.2 001165804.1_53724001_3 - 2.1e-28 99.0 4.6 2.7e-10 39.8 0.1 4.0 1 1 5 6 6 6 5 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001165804.1_53724001_3 - 8.9e-08 32.2 3.2 4.1 8.3 2.2 6.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.4 001165804.1_53724001_3 - 0.00064 20.1 1.9 4.5 7.7 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF3368 PF11848.6 001165804.1_53724001_3 - 0.00077 19.1 2.3 10 5.8 0.0 5.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3368) AEP1 PF17049.3 001165804.1_53724001_3 - 0.0027 16.7 0.0 0.15 11.0 0.0 2.4 1 1 1 2 2 2 1 ATPase expression protein 1 RabGAP-TBC PF00566.16 001165804.1_53724001_3 - 0.041 13.4 0.0 0.082 12.4 0.0 1.5 1 1 0 1 1 1 0 Rab-GTPase-TBC domain ECSIT PF06239.9 001165804.1_53724001_3 - 0.061 12.3 0.3 11 4.9 0.1 3.9 2 1 2 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.4 001165804.1_53724001_3 - 0.1 12.6 0.1 19 5.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.12 001165804.1_53724001_3 - 6.6 7.5 8.2 38 5.2 0.1 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.15 001165813.1_53725001_1 - 1.2e-38 132.7 0.2 3.5e-37 127.9 0.2 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001165813.1_53725001_1 - 8.5e-36 123.5 0.0 8.5e-35 120.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain GUB_WAK_bind PF13947.4 001165813.1_53725001_1 - 4.6e-22 78.7 0.2 2e-21 76.6 0.1 2.3 2 0 0 2 2 2 1 Wall-associated receptor kinase galacturonan-binding EGF_CA PF07645.13 001165813.1_53725001_1 - 2.7e-05 24.1 10.4 2.7e-05 24.1 10.4 3.3 3 0 0 3 3 3 1 Calcium-binding EGF domain WAK PF08488.9 001165813.1_53725001_1 - 0.0034 17.7 0.7 0.0097 16.3 0.7 1.8 1 0 0 1 1 1 1 Wall-associated kinase EGF_3 PF12947.5 001165813.1_53725001_1 - 0.046 13.8 20.0 0.57 10.3 4.3 3.1 2 0 0 2 2 2 0 EGF domain hEGF PF12661.5 001165813.1_53725001_1 - 0.15 12.7 16.6 2.6 8.7 7.3 3.6 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.25 001165813.1_53725001_1 - 0.9 9.8 34.9 0.04 14.1 9.2 3.6 4 0 0 4 4 4 0 EGF-like domain DUF260 PF03195.12 001165602.1_53722001_2 - 8.3e-27 93.4 3.3 1.3e-26 92.7 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF260 LRR_8 PF13855.4 001175899.1_53724001_2 - 9.3e-17 60.4 0.0 1.4e-05 24.6 0.1 5.3 5 0 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.5 001175899.1_53724001_2 - 4.3e-15 55.4 0.0 0.0031 17.7 0.0 6.5 6 1 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001175899.1_53724001_2 - 1.4e-08 33.8 0.1 18 6.2 0.1 8.2 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.4 001175899.1_53724001_2 - 2.6e-08 33.1 1.2 12 6.2 0.0 7.4 8 0 0 8 8 8 2 Leucine Rich repeat LRRNT_2 PF08263.10 001175899.1_53724001_2 - 5.7e-08 32.8 0.1 1.5e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain PTR2 PF00854.19 001176142.1_53725001_3 - 8.7e-98 327.6 4.0 1.2e-97 327.1 4.0 1.2 1 0 0 1 1 1 1 POT family PIG-Y PF15159.4 001176142.1_53725001_3 - 4.2 8.1 8.7 0.92 10.2 3.5 2.7 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Phage_holin_3_6 PF07332.9 001176142.1_53725001_3 - 5.1 7.0 28.8 0.37 10.7 0.2 4.8 4 1 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Reo_sigmaC PF04582.10 001176829.1_53724001_3 - 1 8.5 8.0 4 6.6 0.1 3.2 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Fez1 PF06818.13 001176829.1_53724001_3 - 4.4 7.6 32.9 0.11 12.8 8.0 3.4 1 1 2 3 3 3 0 Fez1 APG6 PF04111.10 001176829.1_53724001_3 - 6.8 5.8 32.0 4.1 6.6 2.3 3.3 1 1 2 3 3 3 0 Autophagy protein Apg6 PALP PF00291.23 001176389.1_53724001_3 - 0.0052 16.1 0.1 0.1 11.9 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Hydrolase PF00702.24 001174517.1_53723001_2 - 1.3e-29 103.9 1.4 1.7e-29 103.5 1.4 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.10 001174517.1_53723001_2 - 5.4e-05 22.9 0.4 0.0039 16.8 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.4 001174517.1_53723001_2 - 0.049 13.6 0.5 0.089 12.7 0.5 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ACT_7 PF13840.4 001174517.1_53723001_2 - 0.18 11.5 1.1 4.4 7.0 0.0 2.7 3 0 0 3 3 3 0 ACT domain Pkinase PF00069.23 001174519.1_53725001_1 - 3.1e-47 161.0 0.0 4.1e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001174519.1_53725001_1 - 1.9e-45 155.1 0.0 2.7e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GUB_WAK_bind PF13947.4 001174519.1_53725001_1 - 4e-08 33.9 0.0 1.8e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Wall-associated receptor kinase galacturonan-binding APH PF01636.21 001174519.1_53725001_1 - 0.0038 17.0 0.0 0.091 12.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.4 001174519.1_53725001_1 - 0.0069 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ABC1 PF03109.14 001174519.1_53725001_1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.12 001174519.1_53725001_1 - 0.1 11.8 0.3 0.23 10.7 0.3 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WAK_assoc PF14380.4 001174519.1_53725001_1 - 0.13 12.9 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal HLH PF00010.24 001174742.1_53723001_2 - 0.0029 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aa_trans PF01490.16 001175911.1_53724001_2 - 3.3e-100 335.5 20.6 3.8e-100 335.3 20.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.11 001175911.1_53724001_2 - 1.5e-06 27.4 5.7 1.5e-06 27.4 5.7 1.8 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family EpuA PF11772.6 001175911.1_53724001_2 - 0.1 12.1 4.3 0.65 9.6 0.9 2.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Nucleo_P87 PF07267.9 001175911.1_53724001_3 - 5.5 5.6 5.5 9.7 4.8 5.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pkinase_Tyr PF07714.15 001174984.1_53722001_1 - 1e-07 31.4 0.0 1.9e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001174984.1_53722001_1 - 4.4e-05 22.8 0.0 5.6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain IBR PF01485.19 001174753.1_53723001_1 - 7.2e-13 48.4 45.7 4.2e-09 36.3 7.5 4.5 2 2 2 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.4 001174753.1_53723001_1 - 7.2e-05 22.5 4.4 7.2e-05 22.5 4.4 4.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.23 001174753.1_53723001_1 - 0.00013 21.6 2.0 0.00013 21.6 2.0 4.2 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001174753.1_53723001_1 - 0.00013 21.6 2.5 0.00013 21.6 2.5 4.9 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001174753.1_53723001_1 - 0.00029 20.9 4.4 0.00029 20.9 4.4 4.0 3 2 0 3 3 3 1 Ring finger domain DUF489 PF04356.10 001176416.1_53725001_3 - 0.041 13.8 1.3 0.1 12.4 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Glyco_hydro_3_C PF01915.20 001176416.1_53725001_3 - 0.059 13.2 0.1 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain CENP-Q PF13094.4 001176416.1_53725001_3 - 6.5 6.8 13.1 0.11 12.6 1.6 3.2 2 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG11 PF10377.7 001175697.1_53722001_3 - 1.9e-18 66.6 0.0 2.9e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 11 Reo_sigmaC PF04582.10 001175697.1_53722001_3 - 0.031 13.6 0.1 0.037 13.3 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein MaoC_dehydratas PF01575.17 001174764.1_53722001_1 - 4.4e-19 68.1 0.1 6.3e-19 67.6 0.1 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.4 001174764.1_53722001_1 - 1.2e-05 25.3 0.0 3e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.20 001174764.1_53722001_1 - 0.066 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Thioesterase superfamily DYW_deaminase PF14432.4 001177255.1_53723001_2 - 2.1e-53 179.4 0.0 1.8e-52 176.4 0.0 2.1 2 0 0 2 2 2 1 DYW family of nucleic acid deaminases PPR PF01535.18 001177255.1_53723001_2 - 1.3e-30 103.3 7.9 9.3e-10 38.0 0.2 6.5 6 0 0 6 6 6 5 PPR repeat PPR_2 PF13041.4 001177255.1_53723001_2 - 5.5e-24 84.0 1.6 2.8e-11 43.3 0.0 5.2 3 2 3 6 6 6 3 PPR repeat family PPR_1 PF12854.5 001177255.1_53723001_2 - 6.2e-17 60.9 0.5 0.00013 21.5 0.0 4.4 3 1 1 4 4 4 3 PPR repeat PPR_3 PF13812.4 001177255.1_53723001_2 - 1.2e-08 34.8 0.0 0.022 14.7 0.0 4.6 3 2 2 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.2 001177255.1_53723001_2 - 8.9e-06 25.1 0.4 0.0027 17.0 0.0 2.9 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PROPR Pkinase_Tyr PF07714.15 001177257.1_53725001_2 - 5.8e-49 166.6 0.0 7.4e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001177257.1_53725001_2 - 2.3e-46 158.2 0.0 3.2e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain GUB_WAK_bind PF13947.4 001177257.1_53725001_2 - 7.3e-27 94.2 0.0 2.8e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Wall-associated receptor kinase galacturonan-binding cEGF PF12662.5 001177257.1_53725001_2 - 0.00071 19.3 5.5 0.00071 19.3 5.5 2.9 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_3 PF12947.5 001177257.1_53725001_2 - 0.00071 19.6 9.8 0.019 15.1 0.9 3.0 2 0 0 2 2 2 2 EGF domain APH PF01636.21 001177257.1_53725001_2 - 0.0057 16.5 1.4 0.083 12.7 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family EGF PF00008.25 001177257.1_53725001_2 - 0.0072 16.5 24.0 0.038 14.1 1.4 3.1 3 0 0 3 3 3 2 EGF-like domain EGF_CA PF07645.13 001177257.1_53725001_2 - 0.0076 16.3 20.6 0.017 15.2 6.8 2.7 2 0 0 2 2 2 2 Calcium-binding EGF domain IL4Ra_N PF09238.8 001177257.1_53725001_2 - 0.019 15.1 0.6 0.049 13.8 0.6 1.6 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal hEGF PF12661.5 001177257.1_53725001_2 - 0.3 11.7 14.2 4.4 8.0 5.3 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF PUL PF08324.9 001175480.1_53726001_3 - 1.5e-56 191.5 3.9 2e-56 191.1 3.9 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.9 001175480.1_53726001_3 - 6.4e-36 122.9 0.1 1.5e-35 121.7 0.1 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.30 001175480.1_53726001_3 - 2.2e-29 100.9 25.9 0.00016 22.3 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat BBS2_Mid PF14783.4 001175480.1_53726001_3 - 0.011 15.6 0.0 5.2 7.0 0.0 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF547 PF04784.12 001174553.1_53723001_2 - 2.3e-19 69.4 0.0 3.5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DUF547 PF04784.12 001174553.1_53723001_3 - 1.7e-06 28.0 0.1 2.7e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF547 F-box-like PF12937.5 001175485.1_53724001_1 - 4.6e-07 29.5 0.0 1.4e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001175485.1_53724001_1 - 0.0022 17.7 0.6 0.0051 16.5 0.0 2.0 2 0 0 2 2 2 1 F-box domain AMP-binding PF00501.26 001175023.1_53723001_3 - 1e-83 281.1 0.0 1.4e-83 280.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001175023.1_53723001_3 - 2.9e-17 63.3 1.7 3.5e-17 63.0 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain tRNA-synt_2 PF00152.18 001175266.1_53725001_3 - 2.4e-107 358.5 0.0 3e-107 358.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.12 001175266.1_53725001_3 - 2.1e-17 63.0 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.23 001175266.1_53725001_3 - 7e-13 48.2 0.2 2.1e-12 46.7 0.1 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.18 001175266.1_53725001_3 - 0.00095 18.6 0.1 0.026 13.9 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.23 001175266.1_53725001_3 - 0.065 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) HATPase_c PF02518.24 001176441.1_53725001_3 - 7.3e-34 116.6 0.0 1.1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Myb_DNA-bind_6 PF13921.4 001176441.1_53725001_3 - 3.3e-08 33.5 0.1 6.9e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.29 001176441.1_53725001_3 - 7e-08 32.4 0.4 1.5e-07 31.3 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_C48 PF02902.17 001175493.1_53725001_3 - 2.7e-34 118.8 0.1 5.5e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pkinase PF00069.23 001175959.1_53726001_3 - 1e-73 247.8 0.0 1.4e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001175959.1_53726001_3 - 1.1e-26 93.6 0.0 1.5e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.30 001175959.1_53726001_3 - 1.1e-23 80.9 2.3 8.6e-07 27.9 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001175959.1_53726001_3 - 5.4e-20 71.5 2.1 1.2e-11 44.7 1.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001175959.1_53726001_3 - 1.1e-16 59.1 1.6 7.8e-05 22.2 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.4 001175959.1_53726001_3 - 5.9e-14 51.4 8.7 8e-08 31.8 0.7 3.9 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.4 001175959.1_53726001_3 - 2.3e-07 29.9 2.8 0.034 13.5 0.1 3.9 4 0 0 4 4 4 2 EF hand Kdo PF06293.12 001175959.1_53726001_3 - 8.3e-06 25.2 0.2 1.9e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.5 001175959.1_53726001_3 - 2.1e-05 24.3 1.0 0.079 12.8 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001175959.1_53726001_3 - 0.00039 20.5 0.2 0.75 10.0 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain Kinase-like PF14531.4 001175959.1_53726001_3 - 0.0015 17.7 0.1 0.0062 15.8 0.1 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.21 001175959.1_53726001_3 - 0.0028 17.5 0.0 1.2 8.8 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family tRNA_synt_1c_R1 PF04558.13 001175959.1_53726001_3 - 0.0028 17.5 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Pox_ser-thr_kin PF05445.9 001175959.1_53726001_3 - 0.0061 15.4 0.0 0.0092 14.9 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Peptidase_M14 PF00246.22 001176448.1_53724001_2 - 4.8e-31 108.5 0.0 6.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase RRM_1 PF00076.20 001175272.1_53724001_2 - 1.1e-35 121.2 0.0 1.8e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001175272.1_53724001_2 - 1.9e-16 59.8 0.1 3.7e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.4 001175272.1_53724001_2 - 0.00059 19.6 0.1 0.062 13.1 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.9 001175272.1_53724001_2 - 0.053 13.1 0.1 1.6 8.3 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain NID PF07292.11 001175272.1_53724001_2 - 0.067 13.7 0.0 0.31 11.6 0.0 2.0 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) PPR_2 PF13041.4 001174572.1_53726001_3 - 8.1e-67 221.1 4.4 1.8e-09 37.5 0.0 14.0 11 2 3 14 14 14 9 PPR repeat family PPR PF01535.18 001174572.1_53726001_3 - 2.4e-61 199.7 15.9 6.9e-08 32.1 0.0 16.2 18 0 0 18 18 18 11 PPR repeat PPR_1 PF12854.5 001174572.1_53726001_3 - 3.6e-40 135.2 2.5 7.1e-06 25.5 0.0 13.5 15 0 0 15 15 15 9 PPR repeat PPR_3 PF13812.4 001174572.1_53726001_3 - 7.1e-22 77.1 0.0 0.00023 21.0 0.0 9.4 8 4 3 11 11 11 4 Pentatricopeptide repeat domain PPR_long PF17177.2 001174572.1_53726001_3 - 1.7e-10 40.5 0.7 0.016 14.4 0.0 5.3 2 1 2 5 5 5 3 Pentacotripeptide-repeat region of PROPR ATP13 PF12921.5 001174572.1_53726001_3 - 0.00049 19.8 0.5 21 4.9 0.0 5.5 6 1 0 7 7 7 2 Mitochondrial ATPase expression Toxin_YhaV PF11663.6 001174572.1_53726001_3 - 0.056 13.4 0.0 52 3.7 0.0 3.2 2 1 1 3 3 3 0 Toxin with endonuclease activity, of toxin-antitoxin system F-box-like PF12937.5 001174574.1_53723001_1 - 3.2e-06 26.8 1.9 5.8e-06 26.0 1.9 1.4 1 0 0 1 1 1 1 F-box-like Zn_ribbon_recom PF13408.4 001174574.1_53723001_1 - 0.082 13.3 0.8 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain F-box_4 PF15966.3 001174574.1_53723001_1 - 0.11 12.2 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 F-box DUF676 PF05057.12 001177095.1_53724001_1 - 4.9e-51 173.2 0.0 7.1e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.11 001177095.1_53724001_1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein RRM_1 PF00076.20 001177298.1_53723001_3 - 4.4e-14 51.9 0.0 6.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPH3 PF03000.12 001174826.1_53725001_2 - 7.4e-88 294.1 0.0 1.7e-87 292.9 0.0 1.6 2 0 0 2 2 2 1 NPH3 family BTB PF00651.29 001174826.1_53725001_2 - 1.4e-08 34.8 0.0 3.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain HSBP1 PF06825.10 001174826.1_53725001_2 - 0.19 11.6 2.8 3 7.7 0.4 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF4618 PF15397.4 001174826.1_53725001_2 - 0.21 10.9 1.1 0.78 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.19 001174826.1_53725001_2 - 2.1 8.4 5.2 0.53 10.3 0.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor CLZ PF16526.3 001174826.1_53725001_2 - 6.1 7.1 6.6 4.7 7.5 0.3 2.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels adh_short PF00106.23 001175763.1_53724001_1 - 1.2e-29 103.0 0.0 1.7e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001175763.1_53724001_1 - 1.9e-22 79.8 0.0 2.9e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001175763.1_53724001_1 - 8.6e-10 38.7 0.2 8.6e-10 38.7 0.2 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.19 001175763.1_53724001_1 - 1.1e-05 24.9 0.2 1.7e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.15 001175763.1_53724001_1 - 0.13 11.2 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.4 001175763.1_53724001_2 - 4.6e-07 29.5 0.0 6.8e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001175763.1_53724001_2 - 4.6e-07 29.3 0.0 6.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Terpene_synth_C PF03936.14 001176255.1_53726001_2 - 7.8e-67 225.3 0.0 1.1e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001176255.1_53726001_2 - 2.4e-46 157.7 0.4 4.6e-46 156.8 0.4 1.5 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain SQHop_cyclase_C PF13243.4 001176255.1_53726001_2 - 0.0084 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.19 001176255.1_53726001_2 - 0.069 12.8 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat LIM_bind PF01803.14 001176012.1_53726001_2 - 4e-59 200.0 0.3 7.1e-59 199.1 0.3 1.4 1 0 0 1 1 1 1 LIM-domain binding protein LETM1 PF07766.11 001175772.1_53724001_3 - 0.83 8.8 4.8 0.3 10.2 0.2 2.3 2 0 0 2 2 2 0 LETM1-like protein Exo_endo_phos PF03372.21 001174843.1_53722001_3 - 0.00094 19.3 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family F-box PF00646.31 001175325.1_53724001_1 - 9.8e-07 28.4 0.0 2.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001175325.1_53724001_1 - 2.3e-05 24.1 1.3 4.1e-05 23.2 0.2 1.9 2 0 0 2 2 2 1 F-box-like Kelch_6 PF13964.4 001175325.1_53724001_1 - 0.11 12.7 0.0 2.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.4 001175325.1_53724001_1 - 0.13 12.1 0.0 70 3.4 0.0 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain IU_nuc_hydro PF01156.17 001176269.1_53726001_2 - 5.7e-71 239.5 0.0 3.5e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase PrmA PF06325.11 001176932.1_53723001_1 - 5.3e-68 229.4 0.0 1.1e-67 228.4 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.4 001176932.1_53723001_1 - 2.1e-07 30.7 0.1 1.2e-06 28.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.12 001176932.1_53723001_1 - 7.1e-07 28.8 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.4 001176932.1_53723001_1 - 3.4e-06 27.5 0.2 5.1e-05 23.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.4 001176932.1_53723001_1 - 3.8e-06 26.8 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001176932.1_53723001_1 - 5.2e-05 23.8 0.1 0.00031 21.3 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 001176932.1_53723001_1 - 0.0013 19.2 0.0 0.0063 17.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.13 001176932.1_53723001_1 - 0.0074 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 BBP7 PF07585.9 001176932.1_53723001_1 - 0.025 13.7 0.0 0.057 12.5 0.0 1.5 2 0 0 2 2 2 0 Putative beta barrel porin-7 (BBP7) Met_10 PF02475.14 001176932.1_53723001_1 - 0.03 14.0 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.5 001176932.1_53723001_1 - 0.032 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF442 PF04273.11 001176932.1_53723001_1 - 0.044 13.7 0.3 0.7 9.9 0.1 2.2 1 1 1 2 2 2 0 Putative phosphatase (DUF442) N6_N4_Mtase PF01555.16 001176932.1_53723001_1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA methylase FBA_3 PF08268.10 001174626.1_53724001_1 - 0.00067 19.5 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 F-box associated domain Kelch_6 PF13964.4 001174626.1_53724001_1 - 0.021 14.9 0.3 13 6.1 0.0 3.1 3 0 0 3 3 3 0 Kelch motif F-box PF00646.31 001174626.1_53724001_1 - 0.032 14.0 0.8 0.089 12.6 0.8 1.7 1 0 0 1 1 1 0 F-box domain SPO11_like PF03533.12 001176274.1_53725001_2 - 0.77 9.8 3.6 0.34 10.9 0.6 2.0 2 0 0 2 2 2 0 SPO11 homologue EMP70 PF02990.14 001176274.1_53725001_3 - 5.9e-217 721.2 7.2 5.9e-217 721.2 7.2 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 DUF3336 PF11815.6 001176937.1_53723001_1 - 3.5e-18 65.5 0.0 5e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.20 001176937.1_53723001_1 - 1.1e-06 28.8 0.2 2.3e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.6 001176937.1_53723001_2 - 0.0024 17.4 0.3 0.0034 16.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) DUF688 PF05097.10 001176511.1_53723001_2 - 0.00056 19.1 3.7 0.00071 18.7 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF688) K_channel_TID PF07941.9 001176511.1_53723001_2 - 0.061 13.7 1.1 0.061 13.7 1.1 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Cofilin_ADF PF00241.18 001174215.1_53723001_1 - 5.6e-29 100.8 0.0 7.1e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2701 PF10857.6 001174215.1_53723001_1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) HLH PF00010.24 001175119.1_53723001_2 - 1.8e-08 34.1 2.0 3.4e-08 33.2 2.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-C2H2 PF00096.24 001175810.1_53726001_1 - 1.4e-05 25.1 11.5 0.0058 16.9 0.2 4.6 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 001175810.1_53726001_1 - 0.0018 18.4 0.1 0.0018 18.4 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001175810.1_53726001_1 - 0.019 15.2 2.1 0.048 13.9 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001175810.1_53726001_1 - 0.033 14.0 1.9 0.098 12.5 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.4 001175810.1_53726001_1 - 0.26 12.1 0.2 0.26 12.1 0.2 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.10 001175810.1_53726001_1 - 2 8.3 5.8 5.3 7.0 4.1 2.4 2 0 0 2 2 2 0 zinc-ribbons Presenilin PF01080.15 001175810.1_53726001_1 - 4.1 5.9 11.5 7.9 5.0 11.5 1.4 1 0 0 1 1 1 0 Presenilin zinc_ribbon_4 PF13717.4 001175810.1_53726001_1 - 8.8 6.2 7.2 2.8 7.8 1.9 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Glyco_hydro_14 PF01373.15 001176536.1_53724001_1 - 1.2e-67 228.5 0.0 1.4e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 LBR_tudor PF09465.8 001175818.1_53726001_2 - 0.016 14.9 0.2 0.031 13.9 0.2 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain UME PF08064.11 001175818.1_53726001_2 - 0.065 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 UME (NUC010) domain C2 PF00168.28 001176971.1_53724001_3 - 1.2e-23 83.2 0.4 2.1e-23 82.4 0.4 1.4 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.3 001176971.1_53724001_3 - 1.5e-16 60.3 0.1 2.4e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain ASFV_p27 PF06556.9 001176971.1_53724001_3 - 0.049 13.6 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus HAD PF12710.5 001174899.1_53724001_1 - 2.2e-08 34.6 0.6 3.7e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.19 001174899.1_53724001_1 - 2.5e-07 30.3 0.0 5.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase AP2 PF00847.18 001177174.1_53723001_3 - 1.7e-11 44.1 1.1 3e-11 43.2 1.1 1.5 1 0 0 1 1 1 1 AP2 domain Kelch_3 PF13415.4 001177176.1_53725001_2 - 7.5e-47 156.7 15.7 1.6e-09 37.7 0.2 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.4 001177176.1_53725001_2 - 2.9e-45 151.8 7.4 2.1e-09 37.0 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.4 001177176.1_53725001_2 - 2.9e-40 135.1 4.0 1.3e-09 37.8 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.23 001177176.1_53725001_2 - 1.5e-37 126.8 18.1 1.2e-09 37.4 0.2 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.4 001177176.1_53725001_2 - 7.7e-35 118.2 10.6 5.9e-09 35.6 0.4 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_2 PF07646.13 001177176.1_53725001_2 - 2.5e-31 106.3 14.4 3.1e-06 26.8 0.2 6.5 6 0 0 6 6 6 6 Kelch motif LCD1 PF09798.7 001177176.1_53725001_2 - 1.4 7.2 5.2 2 6.7 5.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein MatE PF01554.16 001175145.1_53724001_2 - 2.9e-65 218.7 33.1 5.6e-36 123.5 11.4 2.9 3 0 0 3 3 3 2 MatE Rad60-SLD PF11976.6 001177000.1_53722001_3 - 7e-16 57.7 0.6 2.4e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.21 001177000.1_53722001_3 - 1.3e-12 47.1 0.2 1.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin family Pkinase PF00069.23 001177200.1_53723001_3 - 7.4e-49 166.3 0.0 9.3e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001177200.1_53723001_3 - 1.3e-46 158.9 0.0 2.3e-46 158.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001177200.1_53723001_3 - 0.00088 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001177200.1_53723001_3 - 0.052 13.3 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family NUC153 PF08159.10 001174696.1_53722001_2 - 0.00096 18.8 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 NUC153 domain GRP PF07172.9 001174696.1_53722001_2 - 0.29 11.7 22.5 0.51 10.9 22.5 1.5 1 0 0 1 1 1 0 Glycine rich protein family MGDG_synth PF06925.9 001176586.1_53724001_1 - 4.3e-52 176.5 0.0 5.9e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.14 001176586.1_53724001_1 - 3.2e-09 36.8 0.0 5.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.4 001176586.1_53724001_1 - 0.00022 21.5 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA_12 PF13087.4 001175191.1_53728001_1 - 2.1e-50 171.0 0.0 3.6e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.4 001175191.1_53728001_1 - 4.6e-29 101.8 0.0 4.5e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.4 001175191.1_53728001_1 - 1.4e-11 44.4 0.0 3.9e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.4 001175191.1_53728001_1 - 5.1e-10 39.7 0.0 1.1e-08 35.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain UvrD_C PF13361.4 001175191.1_53728001_1 - 5.8e-06 25.8 0.2 0.0056 16.0 0.0 2.5 1 1 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.19 001175191.1_53728001_1 - 0.00036 20.0 0.0 0.0032 16.9 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.13 001175191.1_53728001_1 - 0.00067 19.6 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.14 001175191.1_53728001_1 - 0.0017 17.7 0.0 0.75 9.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.4 001175191.1_53728001_1 - 0.0022 18.2 0.0 0.0054 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.4 001175191.1_53728001_1 - 0.0078 15.9 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.12 001175191.1_53728001_1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Helicase AAA PF00004.27 001175191.1_53728001_1 - 0.0083 16.4 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.16 001175191.1_53728001_1 - 0.0099 15.5 0.1 3.1 7.4 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.16 001175191.1_53728001_1 - 0.012 15.5 0.0 0.085 12.6 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea LTD PF00932.17 001175191.1_53728001_1 - 0.023 14.9 0.0 0.064 13.5 0.0 1.7 2 0 0 2 2 1 0 Lamin Tail Domain AAA_16 PF13191.4 001175191.1_53728001_1 - 0.053 13.8 0.0 0.19 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain Terminase_6 PF03237.13 001175191.1_53728001_1 - 0.062 12.0 0.1 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 Terminase-like family DUF2075 PF09848.7 001175191.1_53728001_1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.27 001175191.1_53728001_1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.19 001175191.1_53728001_1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Proteasome PF00227.24 001176123.1_53725001_3 - 4.7e-50 169.6 0.0 6.6e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001176123.1_53725001_3 - 3.3e-14 52.1 0.1 6e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature 2-oxogl_dehyd_N PF16078.3 001175648.1_53723001_2 - 0.09 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus DUF4216 PF13952.4 001175648.1_53723001_3 - 3.7e-19 68.6 0.1 6.5e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4216) CNDH2_C PF16858.3 001196079.1_53724001_2 - 1.3e-44 153.1 0.0 2e-43 149.2 0.0 2.3 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term COPI_C PF06957.9 001196618.1_53722001_2 - 1.1e-48 166.0 1.0 1.2e-48 165.8 1.0 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus zinc_ribbon_9 PF14369.4 001196618.1_53722001_2 - 0.0034 17.5 0.2 0.0079 16.3 0.2 1.6 1 0 0 1 1 1 1 zinc-ribbon zf-ribbon_3 PF13248.4 001196618.1_53722001_2 - 0.019 14.2 1.1 0.049 12.9 1.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-CHCC PF10276.7 001196618.1_53722001_2 - 0.02 14.8 0.5 0.04 13.9 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger domain Fis1_TPR_C PF14853.4 001196618.1_53722001_2 - 0.067 13.1 0.3 0.1 12.6 0.3 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Pkinase_Tyr PF07714.15 001195915.1_53727001_1 - 4.2e-67 226.0 0.0 5.6e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001195915.1_53727001_1 - 1.2e-59 201.7 0.0 1.8e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PAS PF00989.23 001195915.1_53727001_1 - 8.5e-18 64.3 0.0 2e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.5 001195915.1_53727001_1 - 3.5e-13 49.6 0.0 1e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.8 001195915.1_53727001_1 - 5e-09 36.2 0.0 9.8e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.10 001195915.1_53727001_1 - 4.5e-08 33.1 0.0 1.8e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.5 001195915.1_53727001_1 - 7.4e-08 32.1 0.1 1.6e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.5 001195915.1_53727001_1 - 0.0012 18.9 0.7 0.0024 17.9 0.1 1.8 2 0 0 2 2 2 1 PAS fold APH PF01636.21 001195915.1_53727001_1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS_10 PF13596.4 001195915.1_53727001_1 - 0.072 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 PAS domain DBD_Tnp_Mut PF03108.13 001196547.1_53726001_3 - 2.6e-23 81.4 0.2 6e-23 80.3 0.2 1.6 1 0 0 1 1 1 1 MuDR family transposase MULE PF10551.7 001196547.1_53726001_3 - 4.9e-19 68.5 0.0 1.2e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.15 001196547.1_53726001_3 - 5.1e-06 25.9 1.0 1e-05 24.9 1.0 1.6 1 0 0 1 1 1 1 SWIM zinc finger Transposase_mut PF00872.16 001196547.1_53726001_3 - 0.0029 16.4 0.0 0.0048 15.7 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family zf-C2H2_10 PF16588.3 001196547.1_53726001_3 - 0.005 16.4 3.4 0.015 14.9 3.4 1.9 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.21 001196547.1_53726001_3 - 0.15 12.0 2.0 0.44 10.6 2.0 1.8 1 0 0 1 1 1 0 Zinc knuckle AP2 PF00847.18 001196942.1_53724001_2 - 1.7e-16 60.1 0.6 2.5e-10 40.3 0.1 2.9 2 0 0 2 2 2 2 AP2 domain RRM_1 PF00076.20 001196383.1_53724001_3 - 0.034 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cu-oxidase_3 PF07732.13 001196970.1_53725001_2 - 1.1e-45 154.4 3.4 1.1e-45 154.4 0.6 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.20 001196970.1_53725001_2 - 1.9e-42 144.9 0.4 1.9e-41 141.7 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.12 001196970.1_53725001_2 - 4.9e-40 136.3 9.6 1.3e-38 131.7 0.6 3.6 3 1 0 3 3 3 2 Multicopper oxidase DUF3160 PF11369.6 001196970.1_53725001_2 - 0.036 12.4 0.0 0.054 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) DKCLD PF08068.10 001196976.1_53725001_2 - 1.1e-32 111.7 0.4 1.2e-30 105.3 0.5 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.3 001196976.1_53725001_2 - 3.1e-22 78.3 1.0 7.2e-22 77.2 1.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.18 001196976.1_53725001_2 - 1.1e-21 76.5 1.3 3.1e-21 75.0 1.3 1.9 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.16 001196976.1_53725001_2 - 4.9e-21 75.5 3.2 5.7e-19 68.8 0.1 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Cnl2_NKP2 PF09447.8 001196979.1_53723001_1 - 0.24 11.4 2.1 3.5 7.7 0.4 2.3 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Astro_capsid_p PF12226.6 001196724.1_53723001_3 - 1.6 7.7 7.8 3.1 6.7 7.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.10 001196724.1_53723001_3 - 5.2 5.0 10.9 6.7 4.7 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family Exo_endo_phos PF03372.21 001196735.1_53723001_3 - 6.6e-10 39.1 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RPE65 PF03055.13 001315973.1_06925001_2 - 4.6e-104 348.8 0.0 5.6e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SE PF08491.8 001315831.1_06924001_3 - 3.3e-116 387.0 0.1 4.4e-116 386.6 0.1 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.17 001315831.1_06924001_3 - 1.2e-15 57.5 0.0 2.1e-15 56.7 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.22 001315831.1_06924001_3 - 2e-10 40.7 0.2 1.3e-05 24.9 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.22 001315831.1_06924001_3 - 7.8e-07 28.4 1.1 9.1e-05 21.6 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.4 001315831.1_06924001_3 - 2.2e-06 27.7 0.4 4.3e-06 26.7 0.4 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.20 001315831.1_06924001_3 - 1.5e-05 24.1 0.1 0.015 14.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.12 001315831.1_06924001_3 - 0.00035 19.8 0.0 0.00051 19.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.15 001315831.1_06924001_3 - 0.00045 19.4 0.0 0.00079 18.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.25 001315831.1_06924001_3 - 0.0028 18.1 0.1 0.0085 16.5 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.5 001315831.1_06924001_3 - 0.0062 15.8 1.9 0.0093 15.2 1.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.14 001315831.1_06924001_3 - 0.027 14.0 0.2 0.049 13.1 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.12 001315831.1_06924001_3 - 0.047 12.2 0.1 0.064 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.16 001315831.1_06924001_3 - 0.051 13.3 0.2 0.086 12.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HAMP PF00672.23 001315831.1_06924001_3 - 0.079 13.1 1.5 3.5 7.8 0.2 2.6 2 0 0 2 2 2 0 HAMP domain Trp_halogenase PF04820.12 001315831.1_06924001_3 - 0.12 11.0 0.2 1.6 7.4 0.1 2.2 1 1 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.21 001315831.1_06924001_3 - 0.15 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.10 001315831.1_06924001_3 - 0.15 11.0 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.16 001315831.1_06924001_3 - 0.15 12.2 0.1 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.7 001315831.1_06924001_3 - 0.15 11.7 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain RPE65 PF03055.13 001196999.1_53724001_1 - 9.2e-94 314.8 0.0 1.1e-93 314.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Neurochondrin PF05536.9 001196019.1_53726001_1 - 3.5e-178 593.3 9.4 4.2e-178 593.1 9.4 1.0 1 0 0 1 1 1 1 Neurochondrin Herpes_UL69 PF05459.10 001176713.1_53723001_3 - 0.04 13.1 0.1 0.064 12.5 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family Sugar_tr PF00083.22 001196070.1_53723001_2 - 9e-91 304.9 9.2 1.3e-90 304.3 9.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001196070.1_53723001_2 - 2.2e-23 82.6 44.2 4.6e-19 68.4 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.23 001196090.1_53723001_3 - 1.8e-42 145.4 0.0 2.6e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001196090.1_53723001_3 - 8.9e-27 93.9 0.1 1.5e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001196090.1_53723001_3 - 2.2e-06 27.1 0.4 0.0007 18.9 0.1 2.1 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.20 001196090.1_53723001_3 - 0.035 13.6 0.7 0.07 12.6 0.7 1.4 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.12 001196090.1_53723001_3 - 0.056 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.6 001196090.1_53723001_3 - 0.6 9.6 3.6 0.45 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 MFS_1 PF07690.14 001279422.1_53724001_1 - 2.3e-21 76.0 38.1 2.3e-21 76.0 38.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.23 001279927.1_53724001_1 - 1.6e-70 237.3 0.0 3.7e-70 236.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain EF-hand_1 PF00036.30 001279927.1_53724001_1 - 2e-33 111.3 6.9 1e-07 30.8 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001279927.1_53724001_1 - 1.3e-28 99.1 4.6 3.6e-14 52.9 1.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001279927.1_53724001_1 - 1.4e-26 89.9 2.5 3.3e-07 29.6 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain Pkinase_Tyr PF07714.15 001279927.1_53724001_1 - 1.6e-24 86.5 0.0 2.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_5 PF13202.4 001279927.1_53724001_1 - 2.9e-22 77.0 5.1 5e-05 22.5 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001279927.1_53724001_1 - 6e-19 67.4 8.7 2.4e-08 33.5 0.2 4.4 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.5 001279927.1_53724001_1 - 9e-10 38.3 1.2 0.00026 20.8 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.8 001279927.1_53724001_1 - 7.1e-07 29.1 1.8 0.00097 19.1 0.9 2.5 2 0 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_9 PF14658.4 001279927.1_53724001_1 - 9.7e-07 28.9 0.5 0.0036 17.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.12 001279927.1_53724001_1 - 1.5e-05 24.3 0.1 3.3e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.7 001279927.1_53724001_1 - 0.00013 22.1 0.7 0.11 12.7 0.2 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.21 001279927.1_53724001_1 - 0.0028 17.5 0.5 0.71 9.6 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family tRNA_synt_1c_R1 PF04558.13 001279927.1_53724001_1 - 0.0098 15.8 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Kinase-like PF14531.4 001279927.1_53724001_1 - 0.0099 15.1 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like EF-hand_11 PF08976.9 001279927.1_53724001_1 - 0.037 14.8 0.0 5.7 7.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain Herpes_UL36 PF03586.11 001279927.1_53724001_1 - 0.071 12.3 0.8 2.8 7.1 0.1 2.5 1 1 1 2 2 2 0 Herpesvirus UL36 tegument protein Caleosin PF05042.11 001279927.1_53724001_1 - 0.15 11.8 0.5 36 4.1 0.0 3.1 2 1 1 3 3 3 0 Caleosin related protein Adenine_glyco PF03352.11 001279927.1_53724001_1 - 0.16 11.6 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase Arf PF00025.19 001294310.1_53723001_3 - 1.3e-68 229.8 0.0 1.7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.11 001294310.1_53723001_3 - 4.3e-12 46.2 0.0 6.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.18 001294310.1_53723001_3 - 8.5e-12 44.8 0.3 5.1e-09 35.6 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.8 001294310.1_53723001_3 - 1.3e-09 37.6 0.0 1.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.20 001294310.1_53723001_3 - 2.3e-09 36.9 0.0 3.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.10 001294310.1_53723001_3 - 8.4e-09 35.0 0.0 1.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001294310.1_53723001_3 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 001294310.1_53723001_3 - 0.013 14.6 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DLH PF01738.16 001301451.1_53723001_1 - 2.7e-26 92.3 0.1 3.8e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.19 001301451.1_53723001_1 - 0.01 15.2 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family NTP_transf_3 PF12804.5 001301451.1_53723001_1 - 0.013 15.8 0.3 0.026 14.7 0.3 1.6 1 1 0 1 1 1 0 MobA-like NTP transferase domain PsaN PF05479.9 001301451.1_53723001_1 - 0.08 13.0 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) K_trans PF02705.14 001301494.1_53725001_1 - 8.1e-193 641.6 28.5 9.7e-193 641.4 28.5 1.0 1 0 0 1 1 1 1 K+ potassium transporter Pkinase_Tyr PF07714.15 001301765.1_53724001_2 - 1e-47 162.5 0.0 1.3e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001301765.1_53724001_2 - 1e-47 162.6 0.0 1.5e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF347 PF03988.10 001301765.1_53724001_2 - 0.00098 19.1 0.1 0.0023 17.9 0.1 1.7 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) RCR PF12273.6 001301765.1_53724001_2 - 0.02 15.4 2.8 0.065 13.8 2.8 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red WBP-1 PF11669.6 001301765.1_53724001_2 - 0.1 13.1 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 Pkinase_Tyr PF07714.15 001309879.1_53724001_1 - 9.7e-48 162.6 0.0 1.4e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001309879.1_53724001_1 - 6.1e-40 137.1 0.0 7.5e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.21 001309879.1_53724001_1 - 0.065 13.0 0.0 0.45 10.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.14 001309879.1_53724001_1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Sugar_tr PF00083.22 001158329.2_53725001_3 - 8e-40 136.9 18.5 7.9e-27 94.1 7.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.14 001158329.2_53725001_3 - 2.1e-33 115.6 29.1 9.8e-26 90.4 14.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.12 001158329.2_53725001_3 - 8.9e-06 25.1 22.9 9.7e-05 21.7 10.2 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.4 001158329.2_53725001_3 - 0.00011 20.7 3.1 0.00011 20.7 3.1 3.6 2 2 1 3 3 3 2 MFS/sugar transport protein ThiC_Rad_SAM PF01964.16 001158333.2_53726001_2 - 5.5e-195 647.9 0.0 6.6e-195 647.6 0.0 1.1 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.4 001158333.2_53726001_2 - 6.2e-06 25.8 0.0 1.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 ThiC-associated domain Mem_trans PF03547.16 001158636.2_53725001_3 - 9.9e-163 540.9 0.0 1.5e-162 540.3 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein Aconitase PF00330.18 001317364.1_53727001_2 - 3.5e-183 609.6 0.0 4.7e-183 609.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.17 001317364.1_53727001_2 - 6.6e-50 168.7 0.0 1.3e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Acyl_transf_2 PF02273.13 001317364.1_53727001_2 - 0.082 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase HypD PF01924.14 001317364.1_53727001_2 - 0.097 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Pollen_allerg_1 PF01357.19 001320914.1_53723001_3 - 1.6e-24 85.6 1.1 2.7e-24 84.9 1.1 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001320914.1_53723001_3 - 1.2e-20 73.5 0.0 2.5e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase OMP_b-brl PF13505.4 001320914.1_53723001_3 - 0.032 14.2 5.1 0.057 13.4 5.1 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain RIBIOP_C PF04950.10 001321613.1_53722001_1 - 4.8e-06 26.1 0.0 6.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal RIBIOP_C PF04950.10 001321613.1_53722001_2 - 4.5e-18 65.6 0.0 6.1e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PEP_mutase PF13714.4 001321915.1_53724001_2 - 1.8e-49 168.2 0.7 2.5e-49 167.8 0.7 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.19 001321915.1_53724001_2 - 3e-14 52.3 0.3 4.2e-14 51.8 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family CI-B14_5a PF07347.10 001321915.1_53724001_2 - 0.13 12.1 0.3 0.31 10.8 0.3 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Bap31 PF05529.10 001323361.1_53722001_2 - 0.034 13.6 1.5 0.042 13.3 1.5 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like VGCC_beta4Aa_N PF12052.6 001323361.1_53722001_2 - 0.051 13.6 3.2 0.33 11.0 1.0 2.5 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Lge1 PF11488.6 001323361.1_53722001_2 - 3.8 8.0 5.7 5.3 7.6 1.1 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Herpes_capsid PF06112.9 001323420.1_53722001_1 - 2.2 8.2 12.7 3.1 7.7 12.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Bowman-Birk_leg PF00228.18 001323420.1_53722001_3 - 0.008 16.4 14.0 0.008 16.4 14.0 3.5 4 0 0 4 4 4 2 Bowman-Birk serine protease inhibitor family DUF4228 PF14009.4 001323503.1_53723001_3 - 2.2e-14 54.1 0.4 3.2e-14 53.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) dsrm PF00035.24 001147344.2_53724001_2 - 3.1e-18 66.1 0.1 4.6e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ribonuclease_3 PF00636.24 001147344.2_53724001_2 - 1.4e-17 64.1 0.0 2.8e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.4 001147344.2_53724001_2 - 3.7e-16 59.3 0.2 7.3e-15 55.1 0.2 2.2 1 1 0 1 1 1 1 Ribonuclease-III-like DND1_DSRM PF14709.5 001147344.2_53724001_2 - 3e-10 40.1 0.1 4.2e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 ARD PF03079.12 001326534.1_53723001_2 - 1.4e-65 220.1 0.1 1.9e-65 219.7 0.1 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.9 001326534.1_53723001_2 - 8.1e-10 38.2 0.1 3.3e-09 36.2 0.0 2.0 1 1 1 2 2 2 1 Cupin domain AraC_binding PF02311.17 001326534.1_53723001_2 - 7.9e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.20 001326534.1_53723001_2 - 0.0038 16.7 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Cupin RRM_1 PF00076.20 001328613.1_53725001_2 - 3.9e-16 58.5 0.0 7e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001328613.1_53725001_2 - 0.00022 21.0 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.3 001328613.1_53725001_2 - 0.00059 19.8 0.1 0.0021 18.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif PALP PF00291.23 001329482.1_53723001_2 - 1.3e-59 201.9 0.1 1.6e-59 201.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TFIIB PF00382.17 001329482.1_53723001_2 - 0.0078 16.1 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Abhydrolase_3 PF07859.11 001329482.1_53723001_2 - 0.012 15.4 0.0 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold E3_binding PF02817.15 001329482.1_53723001_2 - 1.6 9.0 3.8 20 5.5 0.1 3.2 3 0 0 3 3 3 0 e3 binding domain PolyA_pol PF01743.18 001346634.1_53725001_3 - 4.3e-29 101.4 0.1 8.4e-29 100.4 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.5 001346634.1_53725001_3 - 8.3e-06 25.3 0.0 1.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Cpn60_TCP1 PF00118.22 001346836.1_53724001_3 - 9.3e-154 512.5 11.0 1.1e-153 512.3 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_3_C PF01915.20 001346836.1_53724001_3 - 0.12 12.2 0.4 0.23 11.3 0.4 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Mg_trans_NIPA PF05653.12 001156548.3_53723001_3 - 8.6e-130 432.0 23.7 1e-129 431.8 23.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.18 001156548.3_53723001_3 - 6.1e-06 26.3 7.8 6.1e-06 26.3 7.8 4.2 3 1 1 4 4 4 1 EamA-like transporter family PepSY_TM PF03929.14 001156548.3_53723001_3 - 0.068 12.4 0.7 0.11 11.7 0.7 1.5 1 1 0 1 1 1 0 PepSY-associated TM region AdoMet_MTase PF07757.11 001156548.3_53723001_3 - 0.077 13.2 0.0 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase DUF3368 PF11848.6 001156548.3_53723001_3 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) EF_TS PF00889.17 001348753.1_53727001_1 - 5.3e-61 205.7 17.1 5.1e-30 104.5 5.0 4.8 3 2 0 3 3 3 2 Elongation factor TS S1 PF00575.21 001348753.1_53727001_1 - 4.3e-22 78.1 2.3 1.4e-15 57.2 0.1 3.3 3 0 0 3 3 3 2 S1 RNA binding domain DPM3 PF08285.9 001348753.1_53727001_1 - 0.00029 20.8 2.0 0.5 10.4 0.1 3.0 3 0 0 3 3 3 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HOIP-UBA PF16678.3 001348753.1_53727001_1 - 0.0006 19.7 4.5 0.078 12.9 1.0 2.4 2 0 0 2 2 2 2 UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase P16-Arc PF04699.12 001348753.1_53727001_1 - 0.16 12.3 1.0 1.8 8.9 0.1 2.7 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) PMEI PF04043.13 001348753.1_53727001_1 - 0.21 11.9 1.4 3.4 8.0 0.2 2.5 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Cyclin_N PF00134.21 001348788.1_53725001_1 - 2.4e-27 95.1 0.0 3.5e-23 81.7 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.17 001348788.1_53725001_1 - 0.00046 20.1 0.3 0.0045 16.9 0.0 2.6 3 0 0 3 3 3 1 Cyclin, C-terminal domain SCP1201-deam PF14428.4 001348788.1_53725001_2 - 0.084 12.6 0.5 0.15 11.8 0.5 1.3 1 0 0 1 1 1 0 SCP1.201-like deaminase Rep_fac-A_3 PF08661.9 001349630.1_53722001_2 - 1.3e-19 70.3 0.0 1.6e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Noc2 PF03715.11 146576.1_53723120_1 - 0.029 13.6 0.1 0.029 13.6 0.1 1.6 2 0 0 2 2 2 0 Noc2p family Noc2 PF03715.11 146576.1_53723120_2 - 3e-33 115.3 0.0 4.5e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Noc2p family S_locus_glycop PF00954.18 146913.1_53723120_3 - 0.0097 16.3 1.0 0.016 15.6 1.0 1.3 1 0 0 1 1 1 1 S-locus glycoprotein domain GST_N PF02798.18 001319764.2_53723001_2 - 6.5e-19 67.9 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001319764.2_53723001_2 - 2.7e-18 66.0 0.0 4.4e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001319764.2_53723001_2 - 2.6e-11 43.6 0.0 4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001319764.2_53723001_2 - 2.2e-07 30.6 0.0 5.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001319764.2_53723001_2 - 1.8e-05 24.7 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 001319764.2_53723001_2 - 3.4e-05 24.4 0.0 8.9e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.4 001319764.2_53723001_2 - 0.054 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.7 001319764.2_53723001_2 - 0.071 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein PP2C PF00481.19 001350856.1_53723001_3 - 5.6e-70 235.8 0.1 1e-58 198.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.10 001350856.1_53723001_3 - 0.00021 21.2 0.0 0.0038 17.0 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.4 001350856.1_53723001_3 - 0.0025 17.4 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Rhodanese PF00581.18 001350856.1_53723001_3 - 0.077 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain Sec8_exocyst PF04048.12 001152721.2_53728001_1 - 2.2e-38 131.2 0.4 5.6e-38 129.9 0.4 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.7 001152721.2_53728001_1 - 0.0003 20.0 0.3 0.00061 19.0 0.3 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex X8 PF07983.11 001350990.1_53725001_1 - 2.7e-20 72.7 0.2 4.4e-20 72.0 0.2 1.4 1 0 0 1 1 1 1 X8 domain EF-hand_1 PF00036.30 001159131.1_53723001_3 - 4.7e-30 100.7 8.1 4.7e-07 28.8 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.4 001159131.1_53723001_3 - 3e-28 98.0 0.0 1.1e-12 48.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001159131.1_53723001_3 - 6.1e-27 91.8 11.7 3.5e-08 32.5 0.0 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.4 001159131.1_53723001_3 - 6.5e-26 89.7 1.5 3.3e-09 36.2 0.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001159131.1_53723001_3 - 8e-24 81.4 0.3 9.6e-07 28.1 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain SPARC_Ca_bdg PF10591.7 001159131.1_53723001_3 - 5e-07 29.9 0.0 0.0046 17.1 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.4 001159131.1_53723001_3 - 3.5e-06 27.1 0.0 0.03 14.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain CCD48 PF15799.3 001159131.1_53723001_3 - 0.011 14.1 2.4 0.014 13.7 2.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 EF-hand_4 PF12763.5 001159131.1_53723001_3 - 0.1 12.4 0.0 18 5.2 0.0 2.3 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Aldedh PF00171.20 001112106.1_53724001_3 - 3.3e-178 592.8 0.0 3.9e-178 592.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PDT PF00800.16 001351094.1_53724001_2 - 3.2e-59 199.7 0.0 4.1e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.23 001351094.1_53724001_2 - 2.9e-05 23.6 0.0 5.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain DnaJ_C PF01556.16 001136845.1_53725001_3 - 1.2e-40 138.8 0.1 1.7e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 001136845.1_53725001_3 - 4.9e-23 80.9 1.4 1e-22 79.9 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.17 001136845.1_53725001_3 - 2.4e-15 56.5 20.2 4.4e-15 55.7 20.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.3 001136845.1_53725001_3 - 1.1e-05 25.2 18.6 0.0088 15.9 4.7 2.5 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.17 001136845.1_53725001_3 - 0.0063 16.4 8.7 0.31 10.9 0.5 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.5 001136845.1_53725001_3 - 0.21 11.5 8.4 3.8 7.5 0.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.10 001136845.1_53725001_3 - 8.7 6.3 10.3 3.1e+02 1.3 10.3 2.3 1 1 0 1 1 1 0 zinc-ribbons EP400_N PF15790.3 001139251.1_53722001_2 - 0.12 11.0 1.9 0.15 10.8 1.9 1.0 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Peptidase_M16 PF00675.18 001157142.1_53725001_2 - 2.6e-34 118.2 0.0 4.7e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001157142.1_53725001_2 - 1.4e-26 93.5 0.0 2e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Raffinose_syn PF05691.10 001154109.1_53726001_2 - 0 1055.2 0.0 0 1054.9 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 zf-C2H2_6 PF13912.4 001153894.1_53722001_3 - 1.3e-05 24.9 1.2 3.6e-05 23.5 1.2 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.4 001153894.1_53722001_3 - 0.039 14.7 0.5 0.039 14.7 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger Actino_peptide PF14408.4 001153894.1_53722001_3 - 0.04 13.9 2.1 0.26 11.3 0.9 2.2 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes CtnDOT_TraJ PF07863.9 001153894.1_53722001_3 - 9.2 6.9 8.7 0.58 10.7 1.1 2.7 3 0 0 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon zf-Tim10_DDP PF02953.13 001158789.1_53722001_3 - 2e-20 72.0 1.8 3.1e-20 71.5 1.8 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Arfaptin PF06456.11 001195909.2_53723001_1 - 0.024 14.1 1.5 0.038 13.4 1.5 1.3 1 0 0 1 1 1 0 Arfaptin-like domain DUF2951 PF11166.6 001195909.2_53723001_1 - 2.4 8.3 7.9 3.5 7.8 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) ATP-synt_I PF03899.13 001176703.2_53725001_1 - 4.7 7.5 7.4 2.5 8.4 4.7 1.9 1 1 1 2 2 2 0 ATP synthase I chain Nitro_FeMo-Co PF02579.15 001301508.2_53722001_2 - 0.12 12.6 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor SRF-TF PF00319.16 001301508.2_53722001_3 - 1.4e-24 85.2 0.2 2.3e-24 84.5 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001301508.2_53722001_3 - 5.7e-23 80.8 10.5 5.7e-23 80.8 10.5 1.6 2 0 0 2 2 2 1 K-box region Acyltransf_C PF16076.3 001112449.1_53724001_1 - 2.1e-22 78.9 0.0 3.8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.19 001112449.1_53724001_1 - 1.7e-15 56.7 0.0 3.7e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF3040 PF11239.6 001112449.1_53724001_1 - 1.2 9.3 7.0 0.36 11.0 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) PLAC8 PF04749.15 001151212.1_53722001_1 - 3.1e-28 98.5 30.5 5.4e-28 97.7 30.5 1.4 1 0 0 1 1 1 1 PLAC8 family PSK PF06404.10 001291566.1_53722001_1 - 0.14 13.1 3.3 0.41 11.5 3.3 1.9 1 1 0 1 1 1 0 Phytosulfokine precursor protein (PSK) PEGSRP PF07623.9 001291566.1_53722001_2 - 0.019 14.6 0.8 0.052 13.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) DSS1_SEM1 PF05160.11 001291676.1_53722001_2 - 4.2e-18 65.0 24.0 5.9e-18 64.6 24.0 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family PK PF00224.19 001111796.2_53724001_2 - 9.2e-154 511.3 0.6 1.2e-153 510.9 0.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.14 001111796.2_53724001_2 - 5.7e-23 81.2 0.3 3.3e-22 78.8 0.2 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.12 001111796.2_53724001_2 - 0.021 13.8 0.2 0.057 12.4 0.1 1.7 1 1 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Pkinase PF00069.23 001111470.2_53725001_3 - 1.2e-73 247.6 0.0 1.5e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001111470.2_53725001_3 - 4.5e-37 127.6 0.0 6.3e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001111470.2_53725001_3 - 1.1e-21 76.7 0.7 1.9e-21 75.9 0.7 1.4 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001111470.2_53725001_3 - 2.4e-09 36.8 0.0 6.6e-08 32.1 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001111470.2_53725001_3 - 0.004 17.0 0.3 0.063 13.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.12 001111470.2_53725001_3 - 0.03 13.5 0.1 0.077 12.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family POX PF07526.9 001111714.2_53723001_3 - 2e-23 83.4 0.0 6.6e-23 81.7 0.0 1.9 2 1 0 2 2 2 1 Associated with HOX Homeobox_KN PF05920.9 001111714.2_53723001_3 - 5.6e-17 61.2 0.1 5.6e-17 61.2 0.1 2.0 3 0 0 3 3 3 1 Homeobox KN domain Homeobox PF00046.27 001111714.2_53723001_3 - 1.7e-06 27.6 0.1 4.9e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Homeobox domain FTCD_C PF04961.10 001111714.2_53723001_3 - 0.019 14.6 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase eIF-3_zeta PF05091.10 001176410.2_53725001_1 - 6.2e-195 649.0 0.0 7.2e-195 648.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.7 001176410.2_53725001_1 - 0.00028 20.3 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus NTP_transf_8 PF12281.6 001176410.2_53725001_1 - 0.024 14.5 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase Swi3 PF07962.10 001294155.1_53723001_1 - 8.9e-21 73.5 0.0 1.3e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 zf-CCHC PF00098.21 001294155.1_53723001_1 - 3.4e-08 33.1 3.1 6.7e-08 32.1 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.4 001294155.1_53723001_1 - 0.0011 18.5 1.8 0.0024 17.4 1.8 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.4 001294155.1_53723001_1 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.4 001294155.1_53723001_1 - 0.012 15.3 3.9 0.022 14.4 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.4 001294155.1_53723001_1 - 0.23 11.1 0.4 0.4 10.3 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle CTP_transf_like PF01467.24 001155473.2_53722001_1 - 6.4e-09 36.0 0.0 8.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.10 001155473.2_53722001_1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase AMP-binding PF00501.26 001154705.2_53725001_1 - 6e-101 337.9 0.1 7.3e-101 337.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001154705.2_53725001_1 - 2.5e-05 25.0 0.1 8.3e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PAP_fibrillin PF04755.10 001153924.2_53722001_2 - 5.8e-32 111.1 0.0 4.2e-31 108.3 0.0 1.9 1 1 0 1 1 1 1 PAP_fibrillin Frigida PF07899.9 001152450.2_53723001_2 - 9.9e-58 195.6 0.6 1.2e-57 195.3 0.6 1.0 1 0 0 1 1 1 1 Frigida-like protein RhlB PF12300.6 001152450.2_53723001_3 - 2.4 8.2 8.5 0.18 11.9 3.1 1.7 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Metallophos PF00149.26 001154507.2_53724001_1 - 3.8e-22 79.7 3.2 6.2e-22 79.0 0.6 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.3 001154507.2_53724001_1 - 4.5e-21 75.1 1.4 4.5e-21 75.1 1.4 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.4 001154507.2_53724001_1 - 2.8e-18 66.4 0.1 7.6e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C DUF4005 PF13178.4 001154198.2_53724001_2 - 6.5e-12 45.8 5.9 6.5e-12 45.8 5.9 3.1 3 1 0 4 4 4 1 Protein of unknown function (DUF4005) IQ PF00612.25 001154198.2_53724001_2 - 1.1e-06 27.8 16.0 6e-06 25.5 1.7 3.6 3 0 0 3 3 3 2 IQ calmodulin-binding motif Pkinase_Tyr PF07714.15 001154728.2_53725001_2 - 8.3e-71 238.2 0.0 1.2e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001154728.2_53725001_2 - 1.2e-57 195.2 0.0 1.7e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ACT PF01842.23 001154728.2_53725001_2 - 8.8e-07 28.5 0.1 3.1e-06 26.7 0.0 1.9 1 1 1 2 2 2 1 ACT domain IU_nuc_hydro PF01156.17 001156971.2_53724001_1 - 2.2e-81 273.6 1.3 2.7e-81 273.3 1.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Yip1 PF04893.15 001154194.2_53723001_3 - 1.9e-12 47.1 14.8 2.8e-12 46.6 14.8 1.2 1 0 0 1 1 1 1 Yip1 domain Sec20 PF03908.11 001157034.2_53723001_1 - 4e-28 97.0 6.8 1.3e-27 95.4 1.5 3.0 2 1 1 3 3 3 1 Sec20 DUF1664 PF07889.10 001157034.2_53723001_1 - 0.0068 16.3 1.6 0.3 10.9 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) DUF211 PF02680.12 001157034.2_53723001_1 - 0.084 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 V-SNARE_C PF12352.6 001157034.2_53723001_1 - 0.14 12.4 5.5 0.33 11.1 2.9 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Trp_syntA PF00290.18 001301469.1_53723001_2 - 3.5e-94 314.4 0.0 4.3e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.19 001301469.1_53723001_2 - 6.7e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.12 001301469.1_53723001_2 - 0.0001 21.6 0.1 0.0002 20.6 0.1 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG PcrB PF01884.15 001301469.1_53723001_2 - 0.00044 19.6 0.1 0.0027 17.1 0.1 2.0 2 0 0 2 2 2 1 PcrB family FMN_dh PF01070.16 001301469.1_53723001_2 - 0.0013 17.7 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.13 001301469.1_53723001_2 - 0.0041 16.4 0.1 0.0041 16.4 0.1 2.1 3 0 0 3 3 3 1 Nitronate monooxygenase NanE PF04131.12 001301469.1_53723001_2 - 0.0066 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.19 001301469.1_53723001_2 - 0.021 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Dus PF01207.15 001301469.1_53723001_2 - 0.028 13.4 0.2 0.059 12.3 0.2 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Ribul_P_3_epim PF00834.17 001301469.1_53723001_2 - 0.03 13.6 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family GTP_EFTU PF00009.25 001301478.1_53724001_3 - 9.1e-54 181.8 0.1 3e-53 180.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001301478.1_53724001_3 - 8.2e-39 132.2 0.0 1.8e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001301478.1_53724001_3 - 4.2e-14 52.6 1.7 4.8e-14 52.4 0.4 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001301478.1_53724001_3 - 0.0015 18.5 0.2 0.0059 16.5 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001301478.1_53724001_3 - 0.0049 16.7 0.2 0.0049 16.7 0.2 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 4 SRPRB PF09439.8 001301478.1_53724001_3 - 0.018 14.3 0.1 0.3 10.4 0.1 2.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FlpD PF02662.14 001301478.1_53724001_3 - 0.03 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit AAA_22 PF13401.4 001301478.1_53724001_3 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Semialdhyde_dhC PF02774.16 001301478.1_53724001_3 - 0.17 11.8 0.3 0.42 10.5 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain zf-RING_2 PF13639.4 001301555.1_53722001_1 - 5.5e-14 52.0 5.8 5.5e-14 52.0 5.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.3 001301555.1_53722001_1 - 1.5e-10 40.5 2.9 1.5e-10 40.5 2.9 2.8 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001301555.1_53722001_1 - 1.2e-09 37.7 5.9 1.2e-09 37.7 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001301555.1_53722001_1 - 3.9e-08 33.3 4.9 3.9e-08 33.3 4.9 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001301555.1_53722001_1 - 3.6e-07 29.8 4.4 3.6e-07 29.8 4.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001301555.1_53722001_1 - 3.6e-07 30.0 5.2 3.6e-07 30.0 5.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 001301555.1_53722001_1 - 4e-06 26.5 4.1 4e-06 26.5 4.1 1.9 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001301555.1_53722001_1 - 0.00026 20.6 5.5 0.00026 20.6 5.5 1.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001301555.1_53722001_1 - 0.00033 20.5 3.3 0.00033 20.5 3.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.4 001301555.1_53722001_1 - 0.00041 20.0 7.0 0.0011 18.6 7.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zf_RING PF16744.3 001301555.1_53722001_1 - 2.2 8.3 7.9 0.089 12.8 1.4 2.0 2 1 1 3 3 3 0 KIAA1045 RING finger FANCL_C PF11793.6 001301555.1_53722001_1 - 2.9 8.0 11.9 0.33 11.0 4.8 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.3 001301555.1_53722001_1 - 4.5 6.8 14.9 0.053 13.0 6.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Tetraspannin PF00335.18 001111815.2_53723001_2 - 6.4e-38 130.5 12.5 8.2e-38 130.2 12.5 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF1772 PF08592.9 001111815.2_53723001_2 - 6.7e-05 23.1 2.0 0.0012 19.0 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) FA_desaturase PF00487.22 001111815.2_53723001_2 - 0.0015 18.3 0.6 0.0015 18.3 0.6 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cadherin_C_2 PF16492.3 001111815.2_53723001_2 - 0.0042 17.7 0.2 0.11 13.1 0.1 2.8 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal DUF2207 PF09972.7 001111815.2_53723001_2 - 0.0044 15.7 1.8 0.0044 15.7 1.8 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) Wzy_C PF04932.13 001111815.2_53723001_2 - 0.023 14.2 0.8 0.48 9.9 0.2 2.2 2 0 0 2 2 2 0 O-Antigen ligase DUF912 PF06024.10 001111815.2_53723001_2 - 0.96 9.7 2.8 36 4.6 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM132D_C PF15706.3 001111815.2_53723001_2 - 1.1 8.9 9.3 9.7 5.9 3.5 2.6 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SAYSvFN PF10260.7 001111815.2_53723001_2 - 2.5 7.9 5.2 2 8.3 1.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF4131 PF13567.4 001111815.2_53723001_2 - 2.9 7.3 11.5 13 5.2 8.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) EI24 PF07264.9 001111815.2_53723001_2 - 5.4 7.1 15.0 33 4.5 15.0 2.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Pkinase PF00069.23 001177007.2_53726001_1 - 1.8e-69 233.9 0.0 2.6e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001177007.2_53726001_1 - 6.9e-31 103.4 8.1 1.7e-07 30.2 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001177007.2_53726001_1 - 3.5e-25 88.1 4.5 4.7e-12 46.1 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001177007.2_53726001_1 - 2.5e-23 79.8 6.4 4.1e-07 29.3 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain Pkinase_Tyr PF07714.15 001177007.2_53726001_1 - 4.2e-23 81.8 0.0 5.9e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.4 001177007.2_53726001_1 - 5.6e-21 73.9 14.0 8.3e-08 31.8 0.6 5.2 2 1 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.4 001177007.2_53726001_1 - 1.4e-20 71.7 6.5 4.7e-05 22.6 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.5 001177007.2_53726001_1 - 5e-09 35.9 0.9 0.0011 18.7 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.12 001177007.2_53726001_1 - 4.4e-05 22.8 0.2 8e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.4 001177007.2_53726001_1 - 0.00038 20.6 1.0 0.36 11.1 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.7 001177007.2_53726001_1 - 0.0039 17.3 0.4 3 8.1 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.4 001177007.2_53726001_1 - 0.043 13.0 0.0 0.33 10.1 0.0 2.1 1 1 0 1 1 1 0 Kinase-like APH PF01636.21 001177007.2_53726001_1 - 0.069 12.9 0.1 4.5 7.0 0.1 2.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family SAP PF02037.25 001177007.2_53726001_1 - 0.077 12.6 0.0 1 9.1 0.0 2.7 3 0 0 3 3 3 0 SAP domain Transket_pyr PF02779.22 001112036.2_53724001_1 - 2.3e-47 160.8 0.0 3.9e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 001112036.2_53724001_1 - 1.8e-42 144.0 0.1 4.1e-42 142.8 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.2 001112036.2_53724001_1 - 0.032 14.4 0.1 0.061 13.5 0.1 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II peroxidase PF00141.21 001112030.2_53723001_1 - 2.3e-45 154.9 0.0 3.3e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase MinE PF03776.12 001111400.2_53722001_3 - 7.2e-16 57.8 1.0 8.4e-16 57.6 0.3 1.5 2 0 0 2 2 2 1 Septum formation topological specificity factor MinE DUF836 PF05768.12 001111400.2_53722001_3 - 0.067 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) OTU PF02338.17 001154131.2_53723001_2 - 9.8e-12 45.3 0.1 1.5e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.7 001154131.2_53723001_2 - 0.061 12.6 0.3 0.47 9.7 0.3 2.1 1 1 1 2 2 2 0 Peptidase C65 Otubain BBP1_C PF15272.4 001154131.2_53723001_2 - 0.085 12.5 0.5 0.15 11.7 0.5 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal CN_hydrolase PF00795.20 001351751.1_53724001_2 - 1.2e-67 227.9 0.0 1.5e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_tranf_2_3 PF13641.4 001138843.2_53724001_1 - 5.6e-23 81.9 0.1 8.3e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.4 001138843.2_53724001_1 - 2.2e-18 66.7 3.3 5.8e-18 65.4 3.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.24 001138843.2_53724001_1 - 4.4e-16 59.0 0.0 9e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.7 001138843.2_53724001_1 - 0.0093 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3148 PF11347.6 001351758.1_53722001_2 - 1.4e-22 79.1 0.1 2.1e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3148) CAF1C_H4-bd PF12265.6 001112086.2_53724001_1 - 7.4e-29 99.7 0.4 1.8e-28 98.5 0.4 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.30 001112086.2_53724001_1 - 4.6e-23 80.9 15.0 4.4e-07 30.4 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001112086.2_53724001_1 - 4.7e-05 23.5 0.6 0.02 15.0 0.0 3.5 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001112086.2_53724001_1 - 0.00046 20.0 0.4 0.19 11.4 0.0 3.1 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Glycolytic PF00274.17 001147365.2_53723001_1 - 5.6e-171 567.8 0.0 6.4e-171 567.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF946 PF06101.9 001151811.2_53725001_3 - 5.5e-247 820.3 0.0 6.4e-247 820.1 0.0 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF498 PF04430.12 001150115.2_53722001_2 - 1.1e-32 112.2 0.0 1.6e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) NTP_transferase PF00483.21 001112588.2_53724001_2 - 1.2e-75 254.2 0.0 1.6e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.22 001112588.2_53724001_2 - 0.0058 16.2 6.8 0.037 13.6 2.2 3.3 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.5 001112588.2_53724001_2 - 0.016 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain ALG3 PF05208.11 001150411.2_53724001_2 - 1.8e-137 458.5 23.5 2.2e-137 458.2 23.5 1.1 1 0 0 1 1 1 1 ALG3 protein RNA_GG_bind PF10258.7 001151751.2_53723001_3 - 3.4e-24 84.5 0.1 5.8e-24 83.8 0.1 1.4 1 0 0 1 1 1 1 PHAX RNA-binding domain IF-2B PF01008.15 001155921.2_53724001_1 - 1.9e-70 237.2 0.2 8.7e-70 235.0 0.2 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family Glyco_hydro_17 PF00332.16 001155947.2_53723001_1 - 2e-91 306.5 0.0 2.3e-91 306.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 adh_short PF00106.23 001156431.2_53724001_2 - 7.6e-22 77.6 0.1 4.4e-20 71.8 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.4 001156431.2_53724001_2 - 5.4e-12 45.6 0.0 8.6e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001156431.2_53724001_2 - 3.7e-09 36.6 0.1 6.2e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.4 001156431.2_53724001_2 - 0.0023 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Eno-Rase_NADH_b PF12242.6 001156431.2_53724001_2 - 0.13 11.9 0.7 0.31 10.7 0.2 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KH_1 PF00013.27 001156434.2_53724001_2 - 6.5e-39 131.5 8.1 8.9e-14 50.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.15 001156434.2_53724001_2 - 1.3e-06 28.0 5.5 0.0076 15.9 0.5 3.3 3 0 0 3 3 3 2 KH domain BMC PF00936.17 001156434.2_53724001_2 - 0.00025 20.8 0.2 0.39 10.6 0.0 2.7 2 0 0 2 2 2 2 BMC domain KH_4 PF13083.4 001156434.2_53724001_2 - 0.0053 16.5 5.6 0.084 12.6 0.2 3.4 4 0 0 4 4 4 1 KH domain Chlorovi_GP_rpt PF06598.9 001156434.2_53724001_2 - 0.016 15.2 0.1 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat KH_5 PF13184.4 001156434.2_53724001_2 - 0.017 15.0 2.5 0.61 10.1 0.2 3.0 3 0 0 3 3 3 0 NusA-like KH domain ALS_ss_C PF10369.7 001156434.2_53724001_2 - 0.13 12.3 0.1 6.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Small subunit of acetolactate synthase CLP1_P PF16575.3 001157693.2_53723001_3 - 3.1e-70 235.7 0.0 4.3e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.12 001157693.2_53723001_3 - 1.1e-32 112.7 0.0 1.8e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.3 001157693.2_53723001_3 - 5.4e-30 103.3 0.0 7.8e-29 99.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.15 001157693.2_53723001_3 - 0.0026 17.4 0.0 0.0064 16.2 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.4 001157693.2_53723001_3 - 0.0077 16.4 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.25 001157693.2_53723001_3 - 0.016 15.6 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.21 001157693.2_53723001_3 - 0.025 14.5 0.0 0.058 13.3 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.5 001157693.2_53723001_3 - 0.058 12.2 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.8 001157693.2_53723001_3 - 0.068 12.5 0.1 0.53 9.6 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.4 001157693.2_53723001_3 - 0.079 12.5 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.21 001157693.2_53723001_3 - 0.13 12.2 0.0 0.37 10.7 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.7 001157693.2_53723001_3 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.18 001157693.2_53723001_3 - 0.14 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Bromodomain PF00439.23 001157746.2_53724001_3 - 1.6e-17 63.2 0.0 2.9e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BET PF17035.3 001157746.2_53724001_3 - 5.6e-17 61.5 2.3 8.4e-17 61.0 2.3 1.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation AF-4 PF05110.11 001157746.2_53724001_3 - 0.053 11.5 2.8 0.086 10.8 2.8 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein EKLF_TAD2 PF16833.3 001157746.2_53724001_3 - 0.057 13.3 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 2 Pmp3 PF01679.15 001158255.2_53722001_3 - 1.6e-17 63.3 5.8 1.6e-17 63.3 5.8 2.2 2 0 0 2 2 2 1 Proteolipid membrane potential modulator UQ_con PF00179.24 001159111.2_53722001_1 - 2.8e-53 179.2 0.0 3.5e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001159111.2_53722001_1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001159111.2_53722001_1 - 0.0055 16.8 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.11 001159111.2_53722001_1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain AUX_IAA PF02309.14 001316741.1_53723001_1 - 1e-55 189.1 3.0 2.6e-53 181.2 3.0 2.9 1 1 0 1 1 1 1 AUX/IAA family PB1 PF00564.22 001316741.1_53723001_1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 PB1 domain Cyclase PF04199.11 001148738.2_53723001_3 - 6.4e-21 74.9 0.0 9.5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase WD40 PF00400.30 001138128.2_53725001_2 - 1.7e-34 117.1 16.4 0.0002 22.0 0.1 10.8 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001138128.2_53725001_2 - 1.9e-11 44.0 0.1 0.24 11.6 0.0 6.0 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.10 001138128.2_53725001_2 - 3.1e-08 33.2 1.8 0.39 10.6 0.2 6.3 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.7 001138128.2_53725001_2 - 3.3e-05 23.6 3.6 0.56 9.8 0.2 3.5 3 1 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.3 001138128.2_53725001_2 - 0.00049 19.0 0.1 0.22 10.3 0.0 3.9 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.9 001138128.2_53725001_2 - 0.00051 19.8 0.1 3.9 7.2 0.0 3.9 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.4 001138128.2_53725001_2 - 0.024 13.7 0.0 0.06 12.4 0.0 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IKI3 PF04762.10 001138128.2_53725001_2 - 0.13 10.1 0.0 11 3.7 0.0 2.6 3 0 0 3 3 3 0 IKI3 family SWIRM-assoc_1 PF16495.3 001317373.1_53726001_1 - 3.6e-26 90.9 7.4 8e-26 89.8 7.4 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM PF04433.15 001317373.1_53726001_1 - 1e-19 70.5 0.0 2.1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.29 001317373.1_53726001_1 - 3.1e-11 43.1 0.1 5.6e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001317373.1_53726001_1 - 1.2e-06 28.5 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.15 001317373.1_53726001_1 - 0.014 15.0 1.4 0.027 14.1 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF4428 PF14471.4 001317373.1_53726001_1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Pkinase PF00069.23 001138671.2_53724001_1 - 9.9e-44 149.5 0.0 1.3e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001138671.2_53724001_1 - 1.8e-42 145.3 0.0 2.4e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.14 001138671.2_53724001_1 - 0.0021 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.21 001138671.2_53724001_1 - 0.0048 16.7 0.1 0.053 13.3 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family NqrM PF04400.11 001138671.2_53724001_1 - 0.076 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 (Na+)-NQR maturation NqrM Tetraspannin PF00335.18 001137122.2_53723001_2 - 5.3e-24 85.1 4.1 5.3e-24 85.1 4.1 1.4 2 0 0 2 2 2 1 Tetraspanin family DUF2207 PF09972.7 001137122.2_53723001_2 - 0.77 8.3 8.0 0.052 12.2 1.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ThrE PF06738.10 001137122.2_53723001_2 - 8.8 5.5 12.1 0.74 9.0 6.6 1.9 2 1 0 2 2 2 0 Putative threonine/serine exporter Metallophos_2 PF12850.5 001137960.2_53723001_1 - 5.6e-17 62.3 0.1 8.2e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.26 001137960.2_53723001_1 - 0.12 12.7 0.3 2.3 8.6 0.3 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Peptidase_C14 PF00656.20 001154268.2_53723001_3 - 4.1e-46 157.8 0.0 5.3e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Thioredoxin PF00085.18 001112288.2_53723001_3 - 4e-66 219.4 0.0 4.9e-32 109.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.10 001112288.2_53723001_3 - 5.7e-26 91.1 0.8 1.2e-25 90.1 0.8 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.4 001112288.2_53723001_3 - 1.5e-15 57.5 0.1 2.1e-06 28.0 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.11 001112288.2_53723001_3 - 2.9e-15 56.2 0.0 1.9e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.19 001112288.2_53723001_3 - 3.3e-09 36.6 0.1 0.0019 18.0 0.0 2.8 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.4 001112288.2_53723001_3 - 1.2e-07 31.7 0.0 0.00049 20.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.4 001112288.2_53723001_3 - 2.1e-07 31.0 0.0 0.06 13.6 0.0 3.9 2 2 2 4 4 4 2 Thioredoxin-like Redoxin PF08534.8 001112288.2_53723001_3 - 0.0013 18.2 0.2 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 Redoxin HyaE PF07449.9 001112288.2_53723001_3 - 0.002 17.9 0.0 0.49 10.3 0.0 2.7 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE TraF PF13728.4 001112288.2_53723001_3 - 0.02 14.6 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein DDE_Tnp_1_2 PF13586.4 001112288.2_53723001_3 - 0.024 14.9 0.0 12 6.2 0.0 2.9 3 0 0 3 3 3 0 Transposase DDE domain Thioredoxin_9 PF14595.4 001112288.2_53723001_3 - 0.11 12.1 0.1 4.3 7.0 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin SBP PF03110.12 001318379.1_53723001_2 - 5.5e-32 109.7 14.4 8.5e-32 109.1 14.4 1.3 1 0 0 1 1 1 1 SBP domain Dscam_C PF12355.6 001318379.1_53723001_2 - 0.15 12.9 0.9 0.45 11.4 0.3 2.1 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Pkinase PF00069.23 001319769.1_53725001_1 - 2.3e-44 151.6 0.0 3.1e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001319769.1_53725001_1 - 1.3e-43 149.1 0.0 1.6e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRRNT_2 PF08263.10 001319769.1_53725001_1 - 5.1e-11 42.5 1.1 1.3e-10 41.3 1.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001319769.1_53725001_1 - 9.3e-09 35.3 15.9 3.9e-05 23.8 2.6 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001319769.1_53725001_1 - 4.7e-07 29.3 14.1 0.00054 19.5 1.5 2.7 1 1 0 2 2 2 2 Leucine rich repeat APH PF01636.21 001319769.1_53725001_1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family LRR_1 PF00560.31 001319769.1_53725001_1 - 0.027 14.7 14.3 8.2 7.2 1.0 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat Kinase-like PF14531.4 001319769.1_53725001_1 - 0.089 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Na_H_Exchanger PF00999.19 001148643.2_53726001_1 - 7e-58 196.1 34.2 9.2e-58 195.7 34.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ATPase_gene1 PF09527.8 001148643.2_53726001_1 - 6.4 6.9 16.9 1.7 8.8 1.7 4.0 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter TFIIIC_sub6 PF10419.7 001148973.2_53722001_2 - 1.8e-11 43.5 0.8 3e-11 42.8 0.8 1.4 1 0 0 1 1 1 1 TFIIIC subunit Kri1_C PF12936.5 001148973.2_53722001_2 - 0.042 13.9 0.4 0.15 12.1 0.1 2.0 2 0 0 2 2 2 0 KRI1-like family C-terminal Cytochrom_C1 PF02167.13 001320251.1_53722001_1 - 0.0048 16.5 0.1 0.31 10.6 0.1 2.1 1 1 0 1 1 1 1 Cytochrome C1 family Cytochrom_C PF00034.19 001320251.1_53722001_1 - 0.12 13.4 0.4 0.18 12.8 0.4 1.3 1 0 0 1 1 1 0 Cytochrome c Pkinase_Tyr PF07714.15 001156339.2_53724001_2 - 7.1e-66 222.0 0.0 9e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001156339.2_53724001_2 - 2.4e-54 184.3 0.0 3.5e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.4 001156339.2_53724001_2 - 0.058 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.21 001156339.2_53724001_2 - 0.085 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC_tran PF00005.25 001320489.1_53725001_1 - 1.1e-45 155.4 0.0 3.8e-22 79.2 0.0 2.7 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.5 001320489.1_53725001_1 - 9.4e-23 79.9 5.7 9.4e-23 79.9 5.7 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.4 001320489.1_53725001_1 - 1.5e-21 77.3 1.1 5.1e-08 32.9 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.17 001320489.1_53725001_1 - 1.5e-09 37.5 0.5 0.096 12.0 0.1 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.4 001320489.1_53725001_1 - 2.7e-07 30.1 0.2 0.0058 16.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.4 001320489.1_53725001_1 - 3.6e-06 27.5 5.5 0.038 14.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.4 001320489.1_53725001_1 - 6.1e-05 22.7 1.9 0.026 14.0 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.21 001320489.1_53725001_1 - 0.00012 22.1 0.0 0.044 13.7 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_33 PF13671.4 001320489.1_53725001_1 - 0.00037 20.5 0.1 0.91 9.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.14 001320489.1_53725001_1 - 0.00089 19.1 0.0 0.16 11.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.4 001320489.1_53725001_1 - 0.0011 19.4 0.5 0.49 10.8 0.0 3.0 3 1 1 4 4 2 1 AAA domain AAA_27 PF13514.4 001320489.1_53725001_1 - 0.0012 18.4 0.1 0.56 9.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.4 001320489.1_53725001_1 - 0.0019 18.5 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.4 001320489.1_53725001_1 - 0.0023 17.8 0.0 4 7.3 0.0 3.3 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.20 001320489.1_53725001_1 - 0.0034 17.6 0.0 2.7 8.3 0.0 2.9 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.4 001320489.1_53725001_1 - 0.0055 16.8 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.4 001320489.1_53725001_1 - 0.006 16.7 0.6 0.19 11.8 0.1 3.0 3 1 0 3 3 3 1 AAA domain NACHT PF05729.10 001320489.1_53725001_1 - 0.016 15.0 0.7 3 7.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.4 001320489.1_53725001_1 - 0.018 14.6 0.1 0.52 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.4 001320489.1_53725001_1 - 0.027 13.9 0.0 2.3 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain phiKZ_IP PF12699.5 001320489.1_53725001_1 - 0.031 13.3 0.1 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins AAA PF00004.27 001320489.1_53725001_1 - 0.032 14.5 0.0 8.8 6.6 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.19 001320489.1_53725001_1 - 0.094 12.0 0.2 13 5.0 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family ArgK PF03308.14 001320489.1_53725001_1 - 0.097 11.5 1.0 9.1 5.0 0.0 2.9 3 0 0 3 3 3 0 ArgK protein Dynamin_N PF00350.21 001320489.1_53725001_1 - 0.17 11.8 1.5 8.3 6.3 0.0 3.4 2 1 1 3 3 3 0 Dynamin family TsaE PF02367.15 001320489.1_53725001_1 - 0.2 11.6 0.6 7.5 6.4 0.0 2.8 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF1180 PF06679.10 001320489.1_53725001_1 - 8.4 6.6 6.2 14 5.9 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) LSM PF01423.20 001157682.2_53722001_3 - 2.1e-18 65.6 2.0 2.9e-18 65.2 2.0 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.6 001157682.2_53722001_3 - 0.029 14.1 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) BPL_C PF02237.15 001157682.2_53722001_3 - 0.074 12.8 0.9 0.15 11.9 0.9 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Jacalin PF01419.15 001154976.2_53723001_3 - 4.8e-26 91.2 0.0 7.5e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain Dirigent PF03018.12 001154976.2_53723001_3 - 3.5e-25 88.5 0.4 6e-25 87.8 0.4 1.4 1 0 0 1 1 1 1 Dirigent-like protein DEAD PF00270.27 001174584.2_53725001_2 - 7.5e-50 169.0 0.0 1.1e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001174584.2_53725001_2 - 4.4e-31 107.4 0.0 7.9e-30 103.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001174584.2_53725001_2 - 0.18 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CDV3 PF15359.4 001174584.2_53725001_2 - 7.3 6.9 8.3 13 6.2 8.3 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 PAP1 PF08601.8 001143070.2_53723001_1 - 0.64 9.6 5.4 0.83 9.2 5.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF538 PF04398.10 001143070.2_53723001_3 - 1.3e-26 93.1 0.0 1.8e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF538 CLTH PF10607.7 001150409.2_53723001_1 - 3.2e-33 114.6 1.0 5.1e-33 113.9 1.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.9 001150409.2_53723001_1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 LisH 4HB_MCP_1 PF12729.5 001150409.2_53723001_1 - 0.037 13.4 0.1 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction EF-hand_1 PF00036.30 001143482.2_53722001_1 - 1.4e-40 133.7 11.5 8.2e-10 37.4 0.6 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001143482.2_53722001_1 - 1.2e-34 118.5 4.0 1.3e-17 63.9 1.3 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.4 001143482.2_53722001_1 - 5.8e-30 102.7 9.2 3e-14 52.4 0.4 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.4 001143482.2_53722001_1 - 3.8e-29 98.0 6.5 4.5e-09 35.4 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001143482.2_53722001_1 - 6.2e-25 85.4 8.5 3.4e-06 26.2 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001143482.2_53722001_1 - 1.3e-15 57.3 0.2 5.9e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001143482.2_53722001_1 - 2e-08 34.0 1.3 0.00015 21.5 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001143482.2_53722001_1 - 1.5e-07 31.6 0.8 0.0044 17.2 0.2 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001143482.2_53722001_1 - 5e-05 24.0 0.1 0.0012 19.5 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.11 001143482.2_53722001_1 - 0.00011 22.1 0.1 0.12 12.3 0.0 2.8 3 1 0 3 3 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.8 001143482.2_53722001_1 - 0.00044 20.2 0.7 0.0017 18.3 0.3 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.14 001143482.2_53722001_1 - 0.0015 18.8 0.1 2.5 8.3 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb4 Caleosin PF05042.11 001143482.2_53722001_1 - 0.0068 16.2 0.2 1.2 8.9 0.0 2.9 1 1 2 3 3 3 1 Caleosin related protein DUF3349 PF11829.6 001143482.2_53722001_1 - 0.0096 16.6 0.3 4.7 7.9 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) MotA_activ PF09114.8 001143482.2_53722001_1 - 0.022 14.7 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain TerB PF05099.11 001143482.2_53722001_1 - 0.023 14.5 0.3 6.4 6.6 0.1 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB Poly_export PF02563.14 001143482.2_53722001_1 - 0.078 13.1 0.0 2.7 8.2 0.0 2.6 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.4 001143482.2_53722001_1 - 0.091 12.5 0.8 1.9 8.2 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF538 PF04398.10 001327742.1_53722001_2 - 1.1e-31 109.5 0.0 1.4e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF538 DUF1817 PF08847.9 001148473.2_53723001_3 - 1.3e-60 203.2 0.0 1.8e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1817) Chloroa_b-bind PF00504.19 001150172.2_53722001_2 - 0.011 16.1 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyll A-B binding protein Ribosomal_L5_C PF00673.19 001158602.2_53723001_2 - 2e-30 104.7 0.0 3.6e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.17 001158602.2_53723001_2 - 1.7e-25 89.0 0.4 4.8e-25 87.5 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Abhydrolase_1 PF00561.18 001159058.2_53724001_1 - 2.7e-18 66.4 0.1 1.1e-11 44.8 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001159058.2_53724001_1 - 1.4e-16 61.7 10.5 1.4e-16 61.7 10.5 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001159058.2_53724001_1 - 0.00098 18.3 0.1 0.0023 17.1 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.8 001159058.2_53724001_1 - 0.023 14.7 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.18 001159058.2_53724001_1 - 0.024 14.6 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Glyco_hydro_10 PF00331.18 001159084.2_53724001_1 - 2.8e-40 138.3 0.0 4.3e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.15 001159084.2_53724001_1 - 0.00034 20.7 0.1 0.0023 18.0 0.0 2.3 3 0 0 3 3 3 1 Carbohydrate binding domain CarboxypepD_reg PF13620.4 001159084.2_53724001_1 - 0.056 13.6 0.3 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Reticulon PF02453.15 001346553.1_53723001_3 - 7.4e-58 194.8 0.6 1e-57 194.3 0.6 1.2 1 0 0 1 1 1 1 Reticulon Metallothio_2 PF01439.16 001346781.1_53722001_2 - 4.2e-26 91.5 37.3 4.2e-26 91.5 37.3 2.0 2 0 0 2 2 2 1 Metallothionein FA_desaturase_2 PF03405.12 001346942.1_53724001_3 - 1.1e-134 448.3 0.0 1.3e-134 448.1 0.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Aa_trans PF01490.16 001346984.1_53724001_1 - 1.7e-70 237.6 22.1 2.1e-70 237.4 22.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2516 PF10724.7 001346984.1_53724001_1 - 6.8 6.9 10.6 0.35 11.0 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) DUF788 PF05620.9 001347193.1_53722001_2 - 0.82 9.4 3.8 1.7 8.4 3.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF788) AP3D1 PF06375.9 001347193.1_53722001_2 - 2.1 8.5 16.7 2.9 8.0 16.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 HILPDA PF15220.4 001347193.1_53722001_3 - 0.17 11.9 1.0 0.37 10.8 1.0 1.5 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated # # Program: hmmscan # Version: 3.1b2 (February 2015) # Pipeline mode: SCAN # Query file: /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/simple/part6/wd/simple6.p.fa # Target file: /home/yduan/database/Pfam/Pfam-A.hmm # Option settings: hmmscan -o /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/simple/part6/hmmscan.outm --tblout /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/simple/part6/hmmscan.t.out /home/yduan/database/Pfam/Pfam-A.hmm /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/simple/part6/wd/simple6.p.fa # Current dir: /home/yduan/work_file/lncRNAdb/methods_assement # Date: Tue Jul 10 03:23:17 2018 # [ok]