# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pkinase_Tyr PF07714.15 001347690.1_53723001_1 - 1.3e-42 145.8 0.0 1.2e-41 142.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.23 001347690.1_53723001_1 - 3.9e-41 141.0 0.0 5.2e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.21 001347690.1_53723001_1 - 0.014 15.1 0.8 0.26 11.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.6 001347690.1_53723001_1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Myb_DNA-binding PF00249.29 001254909.2_53725001_3 - 2e-30 104.5 3.7 4.7e-15 55.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001254909.2_53725001_3 - 1.3e-18 66.8 1.0 6.1e-13 48.7 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001254909.2_53725001_3 - 0.0002 21.3 0.0 0.055 13.4 0.0 2.3 2 0 0 2 2 2 2 SLIDE OPT PF03169.13 001158617.2_53726001_2 - 7.2e-171 569.8 47.8 8.4e-171 569.6 47.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF997 PF06196.10 001158617.2_53726001_2 - 0.2 11.6 0.0 0.2 11.6 0.0 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF997) S1-P1_nuclease PF02265.14 001347905.1_53723001_1 - 1.9e-81 273.5 0.0 2.2e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease MGTL PF17059.3 001347905.1_53723001_1 - 0.043 13.5 0.3 0.11 12.1 0.3 1.8 1 0 0 1 1 1 0 MgtA leader peptide EPF PF17181.2 001151897.2_53722001_2 - 3.3e-18 65.3 1.4 6.1e-18 64.4 1.4 1.5 1 0 0 1 1 1 1 Epidermal patterning factor proteins Cupin_3 PF05899.10 001155186.2_53722001_1 - 7.9e-29 99.0 0.1 1.1e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.9 001155186.2_53722001_1 - 0.028 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Cupin_6 PF12852.5 001155186.2_53722001_1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Ribosomal_L23eN PF03939.11 001348557.1_53722001_3 - 1.1e-17 63.9 11.4 1.1e-17 63.9 11.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.18 001348557.1_53722001_3 - 1.9e-13 50.4 4.8 1.9e-13 50.4 4.8 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Cellulose_synt PF03552.12 001111488.2_53728001_3 - 0 1362.6 0.0 0 1362.2 0.0 1.0 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001111488.2_53728001_3 - 3.3e-36 123.1 9.3 6.8e-36 122.1 9.3 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001111488.2_53728001_3 - 4e-07 30.0 0.2 4e-07 30.0 0.2 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001111488.2_53728001_3 - 3.1e-05 23.5 10.7 3.1e-05 23.5 10.7 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Glycos_transf_2 PF00535.24 001111488.2_53728001_3 - 5e-05 23.1 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 FYVE_2 PF02318.14 001111488.2_53728001_3 - 0.0048 17.0 1.0 0.0048 17.0 1.0 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger Glyco_tranf_2_3 PF13641.4 001111488.2_53728001_3 - 0.1 12.4 0.0 0.66 9.7 0.0 2.3 3 0 0 3 3 3 0 Glycosyltransferase like family 2 Prok-RING_1 PF14446.4 001111488.2_53728001_3 - 0.35 10.7 11.5 2.3 8.1 10.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Band_7 PF01145.23 001348648.1_53723001_1 - 4.1e-30 105.0 1.8 5.2e-30 104.6 1.8 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.4 001348648.1_53723001_1 - 0.0037 16.9 0.2 0.0094 15.5 0.1 1.6 2 0 0 2 2 2 1 SPFH domain-Band 7 family Ribosomal_S3Ae PF01015.16 001348648.1_53723001_1 - 0.0071 15.9 0.8 0.012 15.1 0.8 1.3 1 0 0 1 1 1 1 Ribosomal S3Ae family Pkinase PF00069.23 001115006.3_53724001_2 - 4.5e-73 245.7 0.0 6.6e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001115006.3_53724001_2 - 3.1e-43 147.8 0.0 4.2e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001115006.3_53724001_2 - 1.2e-22 79.7 0.3 2.4e-22 78.7 0.3 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001115006.3_53724001_2 - 3.4e-09 36.3 0.0 2e-08 33.8 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.21 001115006.3_53724001_2 - 0.014 15.2 0.0 0.55 10.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.12 001115006.3_53724001_2 - 0.016 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001115006.3_53724001_2 - 0.019 14.4 0.2 0.045 13.2 0.2 1.6 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.14 001115006.3_53724001_2 - 0.03 14.3 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 ABC1 family RPA_interact_N PF14766.4 001115006.3_53724001_3 - 0.015 14.9 0.2 0.015 14.9 0.2 3.0 3 0 0 3 3 3 0 Replication protein A interacting N-terminal TPT PF03151.14 001136783.2_53723001_1 - 5.2e-11 42.3 16.2 6.7e-11 41.9 16.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family HMA PF00403.24 001348787.1_53723001_3 - 1.5e-15 57.2 2.9 2.5e-15 56.5 2.9 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Longin PF13774.4 001348799.1_53723001_3 - 7.5e-24 83.5 0.1 1.2e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.19 001348799.1_53723001_3 - 2.8e-17 62.1 0.8 5e-17 61.3 0.8 1.4 1 0 0 1 1 1 1 Synaptobrevin T2SSF PF00482.21 001348799.1_53723001_3 - 0.13 12.1 0.1 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F LSM PF01423.20 001159104.2_53722001_2 - 1.2e-05 24.8 0.1 1.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain LSM PF01423.20 001159104.2_53722001_3 - 3.4e-07 29.7 0.1 5e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain TerC PF03741.14 001112780.2_53722001_1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein TerC family Prok-RING_1 PF14446.4 001112780.2_53722001_1 - 0.78 9.6 4.7 1.9 8.3 4.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PBP PF01161.18 001112780.2_53722001_3 - 5e-13 49.4 0.0 7.3e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein AMP-binding PF00501.26 001152403.2_53723001_1 - 7.6e-12 44.4 0.0 1.2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.26 001152403.2_53723001_2 - 5.1e-05 21.9 0.0 6.4e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GRAS PF03514.12 001154365.2_53725001_2 - 1.8e-130 435.1 0.0 2.3e-130 434.8 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family Gal-bind_lectin PF00337.20 001136910.2_53726001_2 - 2.1e-43 146.9 0.0 3.1e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin Galactosyl_T PF01762.19 001136910.2_53726001_2 - 2.2e-31 109.1 0.0 6.4e-31 107.6 0.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.14 001136910.2_53726001_2 - 1.7e-05 24.2 0.1 4.5e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Fringe-like mTERF PF02536.12 001159044.2_53725001_1 - 1.3e-38 132.6 0.0 1.4e-17 63.5 0.0 3.2 2 1 1 3 3 3 3 mTERF Ion_trans PF00520.29 001111770.2_53725001_1 - 5.3e-33 114.1 10.9 7.7e-33 113.6 10.9 1.3 1 0 0 1 1 1 1 Ion transport protein KHA PF11834.6 001111770.2_53725001_1 - 1.3e-21 76.3 0.0 2.8e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel cNMP_binding PF00027.27 001111770.2_53725001_1 - 2.7e-14 52.8 0.0 4.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.14 001111770.2_53725001_1 - 1.9e-12 46.8 1.2 4e-12 45.8 1.2 1.6 1 0 0 1 1 1 1 Ion channel zf-RING_2 PF13639.4 001154069.2_53724001_1 - 3.5e-13 49.4 12.7 3.5e-13 49.4 12.7 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.3 001154069.2_53724001_1 - 7.2e-08 31.9 10.6 2.4e-07 30.2 10.6 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.5 001154069.2_53724001_1 - 1.1e-07 31.9 9.9 3.2e-07 30.4 9.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.4 001154069.2_53724001_1 - 1.2e-06 28.2 12.5 4.6e-06 26.2 12.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001154069.2_53724001_1 - 1e-05 25.2 12.1 1e-05 25.2 12.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001154069.2_53724001_1 - 0.058 13.3 8.7 0.19 11.7 8.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Inositol_P PF00459.23 001156033.2_53723001_2 - 5.3e-74 249.0 0.0 6.5e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Thiolase_N PF00108.21 001349932.1_53724001_1 - 4.1e-77 258.9 2.0 5.6e-77 258.5 2.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.16 001349932.1_53724001_1 - 8.8e-48 160.9 0.7 1.6e-47 160.0 0.7 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.8 001349932.1_53724001_1 - 0.021 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.24 001349932.1_53724001_1 - 0.11 11.9 0.2 0.11 11.9 0.2 3.3 4 0 0 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain Glutaredoxin PF00462.22 001156291.2_53725001_2 - 1.8e-53 178.5 0.0 2.6e-16 59.5 0.0 4.6 4 0 0 4 4 4 3 Glutaredoxin Thioredoxin PF00085.18 001156291.2_53725001_2 - 9.1e-15 54.3 0.1 3.4e-14 52.5 0.1 2.0 1 0 0 1 1 1 1 Thioredoxin SH3BGR PF04908.13 001156291.2_53725001_2 - 2.1e-06 27.7 0.0 0.71 9.9 0.0 3.7 3 0 0 3 3 3 3 SH3-binding, glutamic acid-rich protein Thioredoxin_2 PF13098.4 001156291.2_53725001_2 - 0.0016 18.7 0.2 0.012 16.0 0.0 2.5 2 2 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.9 001156291.2_53725001_2 - 0.029 14.2 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE TrbC_Ftype PF09673.8 001156291.2_53725001_2 - 0.14 12.0 0.1 0.41 10.6 0.1 1.8 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Pectinesterase PF01095.17 001350200.1_53724001_1 - 1.7e-128 427.4 0.2 3e-128 426.6 0.2 1.4 1 1 0 1 1 1 1 Pectinesterase PMEI PF04043.13 001350200.1_53724001_1 - 2.1e-10 41.1 5.0 2.1e-10 41.1 5.0 1.8 2 0 0 2 2 2 1 Plant invertase/pectin methylesterase inhibitor HLH PF00010.24 001350318.1_53725001_1 - 2.6e-15 56.0 0.8 5e-15 55.1 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cnd1 PF12717.5 146273.1_53723120_2 - 9.2e-07 28.9 0.1 1.6e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Cnd1 PF12717.5 146273.1_53723120_3 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.23 146330.1_53723120_3 - 0.0004 19.7 0.0 0.00056 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain adh_short PF00106.23 146328.1_53723120_2 - 2.1e-17 63.1 0.1 2.9e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 146328.1_53723120_2 - 3.9e-10 39.6 0.0 6.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 146328.1_53723120_2 - 4.8e-05 23.2 0.1 7.8e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.4 146328.1_53723120_2 - 0.002 17.9 0.3 0.003 17.4 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.19 146328.1_53723120_2 - 0.0057 16.0 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.23 146328.1_53723120_3 - 1.1e-14 54.2 0.0 6.1e-06 25.7 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.4 146328.1_53723120_3 - 1.3e-10 41.1 0.0 4.3e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF588 PF04535.10 146348.1_53722120_1 - 7.8e-26 90.5 4.6 1.3e-25 89.8 4.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF588) MARVEL PF01284.21 146348.1_53722120_1 - 2.6e-08 33.9 3.5 7.4e-08 32.4 3.4 1.8 1 1 0 1 1 1 1 Membrane-associating domain Ras PF00071.20 146577.1_53722120_1 - 3.3e-05 23.4 0.0 4.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ras family DEAD PF00270.27 001152362.2_53725001_2 - 5.5e-46 156.4 0.7 2.5e-45 154.2 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001152362.2_53725001_2 - 5.6e-23 81.3 0.5 6.2e-21 74.7 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.13 001152362.2_53725001_2 - 5.2e-09 36.2 0.0 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4556 PF15094.4 001152362.2_53725001_2 - 0.077 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Spc24 PF08286.9 001151414.2_53722001_2 - 0.0044 17.1 7.6 0.0065 16.6 6.1 1.9 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Mnd1 PF03962.13 001151414.2_53722001_2 - 0.0067 16.2 8.2 0.0098 15.6 8.2 1.1 1 0 0 1 1 1 1 Mnd1 family APG6 PF04111.10 001151414.2_53722001_2 - 0.01 15.1 8.4 0.013 14.8 8.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF106 PF01956.14 001151414.2_53722001_2 - 0.58 9.7 2.2 1.1 8.9 2.2 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 Atg14 PF10186.7 001151414.2_53722001_2 - 1.9 7.3 13.0 1.6 7.6 11.4 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Epimerase PF01370.19 001155409.2_53724001_3 - 2.4e-20 72.9 0.0 3.3e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001155409.2_53724001_3 - 2.2e-14 53.0 0.0 3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001155409.2_53724001_3 - 2.2e-11 43.9 0.0 3.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.11 001155409.2_53724001_3 - 4e-09 36.2 0.0 5.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.10 001155409.2_53724001_3 - 5.8e-09 35.4 0.0 5.1e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.3 001155409.2_53724001_3 - 2e-07 30.6 0.0 3.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.8 001155409.2_53724001_3 - 0.00043 20.1 0.0 0.0057 16.5 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.23 001155409.2_53724001_3 - 0.0041 16.5 0.1 0.022 14.1 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.13 001155409.2_53724001_3 - 0.0077 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RAWUL PF16207.3 001155409.2_53724001_3 - 0.021 15.3 0.3 0.046 14.2 0.0 1.7 2 0 0 2 2 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF1731 PF08338.9 001155409.2_53724001_3 - 0.028 14.1 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) GST_N_4 PF17172.2 001351851.1_53723001_3 - 2.7e-16 60.0 0.0 4.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.2 001351851.1_53723001_3 - 6.3e-15 54.6 0.3 1.5e-14 53.3 0.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.7 001351851.1_53723001_3 - 2.6e-09 37.3 0.0 4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SR-25 PF10500.7 001351851.1_53723001_3 - 0.002 17.6 3.9 0.0031 17.0 3.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Epimerase PF01370.19 001351827.1_53723001_1 - 2.3e-19 69.7 0.0 3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001351827.1_53723001_1 - 3.5e-13 49.1 0.0 4.7e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001351827.1_53723001_1 - 5.8e-12 45.8 0.0 9.2e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.11 001351827.1_53723001_1 - 1.7e-10 40.7 0.0 2.4e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.3 001351827.1_53723001_1 - 6.4e-09 35.5 0.0 2.2e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.10 001351827.1_53723001_1 - 2.1e-06 27.0 0.0 5.4e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.23 001351827.1_53723001_1 - 0.00022 20.6 0.0 0.0016 17.8 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001351827.1_53723001_1 - 0.0014 18.4 0.0 0.026 14.3 0.0 2.1 1 1 0 1 1 1 1 KR domain DUF1731 PF08338.9 001351827.1_53723001_1 - 0.0048 16.6 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) RAWUL PF16207.3 001351827.1_53723001_1 - 0.015 15.8 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Polysacc_synt_2 PF02719.13 001351827.1_53723001_1 - 0.027 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001351827.1_53723001_1 - 0.055 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PK_C PF02887.14 147837.1_53724120_2 - 0.17 12.0 0.2 0.25 11.4 0.2 1.2 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain AMPK1_CBM PF16561.3 001112085.2_53725001_3 - 2.6e-26 91.5 0.0 8.6e-26 89.9 0.0 1.9 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase CBS PF00571.26 001112085.2_53725001_3 - 3.3e-23 81.7 0.0 1e-07 32.1 0.0 4.3 4 0 0 4 4 4 3 CBS domain GST_N PF02798.18 001111518.2_53722001_1 - 4.1e-16 58.9 0.0 6.8e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001111518.2_53722001_1 - 1.8e-14 53.7 0.0 3.4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001111518.2_53722001_1 - 2.9e-13 49.8 0.0 5.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001111518.2_53722001_1 - 1.1e-09 38.2 0.1 1.8e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001111518.2_53722001_1 - 5.5e-07 29.3 0.9 1e-06 28.4 0.9 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001111518.2_53722001_1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 001111518.2_53722001_1 - 0.03 14.9 0.0 0.087 13.5 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.7 001111518.2_53722001_1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein COG7 PF10191.7 001352022.1_53726001_1 - 0 1036.8 0.4 0 1036.6 0.4 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) Sec10 PF07393.9 001352022.1_53726001_1 - 0.22 9.7 5.5 3.8 5.7 0.1 2.6 2 1 0 2 2 2 0 Exocyst complex component Sec10 GASA PF02704.12 001288163.1_48621001_1 - 2.4e-21 75.5 25.3 3e-21 75.2 25.3 1.1 1 0 0 1 1 1 1 Gibberellin regulated protein FBPase PF00316.18 001157234.2_53724001_3 - 1.1e-56 191.3 1.0 1.6e-56 190.7 1.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain RskA PF10099.7 001157234.2_53724001_3 - 1.9 8.6 9.8 3.3 7.8 9.8 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA LTP_2 PF14368.4 001352160.1_53722001_3 - 2e-12 46.9 4.8 3.3e-12 46.2 4.8 1.3 1 0 0 1 1 1 1 Probable lipid transfer Tryp_alpha_amyl PF00234.20 001352160.1_53722001_3 - 1.1e-06 28.8 1.7 1.9e-06 28.1 1.7 1.3 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family Ribonuc_red_sm PF00268.19 001137436.2_53723001_3 - 5.8e-117 390.0 0.0 7e-117 389.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TAXi_N PF14543.4 001137052.2_53723001_3 - 3.3e-48 164.1 4.1 6.5e-48 163.2 3.6 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.4 001137052.2_53723001_3 - 9.4e-29 100.1 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.21 001137052.2_53723001_3 - 2.5e-16 59.9 0.0 1.3e-14 54.2 0.0 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease RXLR PF16810.3 001137052.2_53723001_3 - 0.016 15.5 0.8 0.024 15.0 0.8 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity zf-RNPHF PF08080.10 001137052.2_53723001_3 - 1.6 8.6 7.6 2 8.3 0.3 3.3 3 0 0 3 3 3 0 RNPHF zinc finger REV PF00424.16 001138482.2_53722001_1 - 2.5 8.1 12.0 1.3 8.9 2.1 2.3 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) tRNA_bind PF01588.18 001148505.2_53723001_2 - 9.2e-31 105.7 0.0 1.8e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Glyco_transf_29 PF00777.16 001322925.1_53723001_1 - 9.4e-29 100.5 0.1 2.9e-18 66.1 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 29 (sialyltransferase) Pkinase PF00069.23 001322954.1_53724001_1 - 4.3e-42 144.2 0.0 6.4e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001322954.1_53724001_1 - 6.4e-37 127.1 0.0 1.8e-36 125.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001322954.1_53724001_1 - 7.7e-05 22.6 4.1 0.0069 16.2 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family RES PF08808.9 001322954.1_53724001_1 - 0.045 13.5 0.2 0.082 12.6 0.2 1.4 1 0 0 1 1 1 0 RES domain Pyridoxal_deC PF00282.17 001323601.1_53724001_2 - 9.2e-24 83.7 0.0 5.5e-23 81.1 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.17 001323601.1_53724001_2 - 0.057 12.2 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V p450 PF00067.20 001147995.3_53724001_1 - 9.8e-58 195.9 0.0 1.2e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAM-associated PF14303.4 001318096.1_53723001_3 - 4.4e-22 79.3 9.9 4.4e-22 79.3 9.9 2.5 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain Macoilin PF09726.7 001318096.1_53723001_3 - 0.83 8.0 7.2 1.7 7.0 7.2 1.4 1 0 0 1 1 1 0 Transmembrane protein DUF563 PF04577.12 001323340.1_53724001_3 - 2.8e-19 69.9 0.0 5.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Dimer_Tnp_hAT PF05699.12 001310028.1_53724001_3 - 0.034 13.8 0.1 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region PWWP PF00855.15 001320896.1_53726001_2 - 0.0061 16.9 0.1 0.022 15.1 0.1 2.0 2 0 0 2 2 2 1 PWWP domain Usp PF00582.24 001156158.2_53722001_3 - 7.8e-19 68.4 0.0 1.2e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Ribosomal_S24e PF01282.17 001112165.2_53723001_2 - 5.6e-38 128.7 0.2 9.4e-38 127.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S26e PF01283.17 001309872.1_53722001_2 - 5.2e-52 174.7 9.2 6.6e-52 174.4 9.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e FAM27 PF15832.3 001309872.1_53722001_2 - 0.059 13.8 0.7 0.059 13.8 0.7 1.7 2 0 0 2 2 2 0 FAM27 D and E protein family Telomere_reg-2 PF10193.7 001309855.1_53727001_2 - 6.3e-26 90.8 0.0 2e-25 89.2 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein LRR_8 PF13855.4 001348141.1_53728001_3 - 3.4e-33 113.1 57.7 4e-10 39.2 0.8 10.3 4 2 5 12 12 12 9 Leucine rich repeat LRR_4 PF12799.5 001348141.1_53728001_3 - 6.7e-33 111.9 54.8 1.8e-05 24.8 0.2 12.0 7 2 6 14 14 14 11 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.15 001348141.1_53728001_3 - 3.4e-26 91.9 0.0 5.9e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001348141.1_53728001_3 - 4.5e-22 78.5 0.0 6.9e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_1 PF00560.31 001348141.1_53728001_3 - 3.3e-19 66.2 42.5 2 9.1 0.0 18.8 18 2 0 18 18 18 5 Leucine Rich Repeat LRR_6 PF13516.4 001348141.1_53728001_3 - 1.4e-10 40.2 51.6 0.95 9.6 0.2 15.8 18 0 0 18 18 18 6 Leucine Rich repeat LRRNT_2 PF08263.10 001348141.1_53728001_3 - 1.1e-09 38.3 0.1 3e-09 36.9 0.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain EphA2_TM PF14575.4 001348141.1_53728001_3 - 0.14 12.8 0.0 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Myb_DNA-binding PF00249.29 001245094.2_53726001_1 - 0.00091 19.2 0.1 0.0018 18.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aa_trans PF01490.16 001111647.2_53725001_2 - 3e-74 250.1 15.7 3.9e-74 249.7 15.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YjcQ PF09639.8 001150877.2_53723001_1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 YjcQ protein LTP_2 PF14368.4 001150877.2_53723001_2 - 2.1e-08 34.0 2.2 2.1e-08 34.0 2.2 1.8 1 1 1 2 2 2 1 Probable lipid transfer Tryp_alpha_amyl PF00234.20 001150877.2_53723001_2 - 0.0018 18.5 2.3 0.0033 17.7 2.3 1.4 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family zf-RING_2 PF13639.4 001148884.2_53724001_3 - 1.2e-13 51.0 6.2 2.7e-13 49.8 6.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001148884.2_53724001_3 - 2.7e-12 46.1 2.4 6.6e-12 44.8 2.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001148884.2_53724001_3 - 6.9e-08 32.1 4.8 1.3e-07 31.2 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001148884.2_53724001_3 - 9.7e-08 32.1 6.7 3.7e-07 30.2 6.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001148884.2_53724001_3 - 5.4e-07 29.2 3.6 9.7e-07 28.4 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001148884.2_53724001_3 - 4.4e-06 26.4 2.9 8.9e-06 25.5 2.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001148884.2_53724001_3 - 1.5e-05 24.7 3.0 3.6e-05 23.6 3.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 001148884.2_53724001_3 - 0.00032 20.3 2.4 0.00032 20.3 2.4 2.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001148884.2_53724001_3 - 0.00041 20.2 1.3 0.00083 19.2 1.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.4 001148884.2_53724001_3 - 0.0013 18.4 3.7 0.0029 17.3 3.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.6 001148884.2_53724001_3 - 0.0041 17.1 2.5 0.011 15.8 2.5 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.4 001148884.2_53724001_3 - 0.01 15.6 0.8 0.65 9.8 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Arc PF03869.12 001148884.2_53724001_3 - 0.062 13.0 0.4 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Arc-like DNA binding domain RINGv PF12906.5 001148884.2_53724001_3 - 0.085 12.9 4.5 0.17 11.9 4.5 1.5 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.3 001148884.2_53724001_3 - 0.11 12.0 6.5 0.22 11.0 6.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.27 001148884.2_53724001_3 - 0.14 11.9 2.7 0.43 10.4 2.8 1.8 1 1 0 1 1 1 0 PHD-finger Rad50_zn_hook PF04423.12 001148884.2_53724001_3 - 0.28 10.9 0.1 0.28 10.9 0.1 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING-like PF08746.9 001148884.2_53724001_3 - 3.8 7.8 5.9 10 6.4 5.9 1.8 1 1 0 1 1 1 0 RING-like domain SCAMP PF04144.11 001346770.1_53723001_2 - 1.6e-53 181.5 15.7 2e-53 181.1 15.7 1.1 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.6 001346770.1_53723001_2 - 0.072 12.4 5.3 0.13 11.6 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.12 001346770.1_53723001_2 - 0.19 11.6 3.1 0.29 11.0 3.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Adaptin_N PF01602.18 001322360.1_53727001_3 - 3.3e-84 283.2 1.8 6e-84 282.3 1.8 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.4 001322360.1_53727001_3 - 1.4e-61 206.0 0.1 3e-61 204.9 0.1 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.10 001322360.1_53727001_3 - 1e-59 200.3 0.2 1.8e-59 199.5 0.2 1.4 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.4 001322360.1_53727001_3 - 6.3e-06 26.4 1.9 0.0044 17.2 0.0 4.2 1 1 2 3 3 3 1 HEAT repeats Cnd1 PF12717.5 001322360.1_53727001_3 - 0.0017 18.2 0.9 0.16 11.8 0.0 3.8 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.3 001322360.1_53727001_3 - 0.006 16.6 0.0 0.1 12.6 0.0 2.7 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Alpha_adaptinC2 PF02883.18 001322360.1_53727001_3 - 0.052 13.7 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Adaptin C-terminal domain RAG2 PF03089.12 001322360.1_53727001_3 - 0.09 11.6 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Recombination activating protein 2 Gemini_V2 PF01524.15 001322360.1_53727001_3 - 0.14 12.2 0.2 5.9 7.0 0.0 3.2 3 0 0 3 3 3 0 Geminivirus V2 protein HEAT PF02985.20 001322360.1_53727001_3 - 2.6 8.4 6.3 43 4.6 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat DUF793 PF05633.9 001323634.1_53724001_2 - 4.5e-123 410.9 0.0 5.4e-123 410.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF793) DUF241 PF03087.12 001323634.1_53724001_2 - 0.001 18.9 0.9 0.28 10.9 0.0 2.3 2 0 0 2 2 2 2 Arabidopsis protein of unknown function UCR_hinge PF02320.14 132277.2_53722120_3 - 1.7e-22 79.3 6.2 2.4e-22 78.8 6.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.10 132277.2_53722120_3 - 0.088 13.0 4.7 3.9 7.7 0.5 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0203) MFS_1 PF07690.14 145696.1_53724120_3 - 1.5e-25 89.8 30.7 1.5e-25 89.8 30.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily CcmD PF04995.12 145696.1_53724120_3 - 0.75 9.8 3.2 3 7.8 3.2 2.1 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PTR2 PF00854.19 145696.1_53724120_3 - 5 5.7 16.9 1.2 7.7 2.0 2.4 2 0 0 2 2 2 0 POT family PPR_2 PF13041.4 145708.1_53726120_2 - 6.4e-26 90.2 7.2 3.5e-07 30.2 0.1 6.0 5 1 1 6 6 6 5 PPR repeat family PPR_3 PF13812.4 145708.1_53726120_2 - 3e-18 65.5 0.1 0.00019 21.3 0.4 4.5 3 1 1 4 4 4 4 Pentatricopeptide repeat domain PPR PF01535.18 145708.1_53726120_2 - 5e-17 60.8 10.5 0.0008 19.4 0.2 6.9 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.5 145708.1_53726120_2 - 2.7e-11 42.8 8.6 0.0038 16.8 0.4 6.8 7 0 0 7 7 7 4 PPR repeat PPR_long PF17177.2 145708.1_53726120_2 - 8.4e-06 25.2 0.1 0.018 14.3 0.1 3.0 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PROPR SAPS PF04499.13 144511.1_53724120_1 - 6.4e-08 31.7 0.1 8.6e-08 31.3 0.1 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF3248 PF11609.6 121039.1_53721120_2 - 0.071 12.9 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3248) DUF1966 PF09260.9 121071.1_53721120_2 - 0.015 15.4 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) 4HBT PF03061.20 001112210.2_53722001_3 - 0.0022 18.2 0.5 0.0085 16.3 0.1 2.2 2 1 1 3 3 3 1 Thioesterase superfamily Prefoldin_2 PF01920.18 001111673.2_53722001_3 - 4.1e-24 84.5 6.9 5e-24 84.2 6.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit PLAC9 PF15205.4 001111673.2_53722001_3 - 0.15 12.4 0.3 0.33 11.3 0.3 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 PCRF PF03462.16 001111673.2_53722001_3 - 0.43 10.3 3.8 0.64 9.7 3.8 1.2 1 0 0 1 1 1 0 PCRF domain DUF4140 PF13600.4 001111673.2_53722001_3 - 1.1 9.7 4.0 14 6.0 0.2 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin PF02996.15 001111673.2_53722001_3 - 1.8 8.4 6.8 0.81 9.5 1.9 2.1 1 1 1 2 2 2 0 Prefoldin subunit DivIC PF04977.13 001111673.2_53722001_3 - 5.8 6.6 7.6 4.9 6.9 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator Copper-bind PF00127.18 001137975.2_53722001_1 - 5e-34 116.6 0.0 7.2e-34 116.0 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.4 001137975.2_53722001_1 - 8.7e-08 32.1 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain DUF908 PF06012.10 001137975.2_53722001_2 - 0.32 10.2 3.6 0.44 9.8 3.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Joubert PF15392.4 001137975.2_53722001_2 - 1.7 8.1 8.9 2.1 7.8 8.9 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated SQAPI PF16845.3 001308502.1_53723001_2 - 1.4e-21 76.5 1.6 5.9e-18 64.9 0.2 2.2 2 0 0 2 2 2 2 Aspartic acid proteinase inhibitor Cystatin PF00031.19 001308502.1_53723001_2 - 3.6e-19 68.7 0.1 3.9e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Cystatin domain Monellin PF09200.8 001308502.1_53723001_2 - 0.094 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Monellin KASH PF10541.7 001308502.1_53723001_2 - 0.22 11.7 1.9 11 6.3 0.3 2.4 2 0 0 2 2 2 0 Nuclear envelope localisation domain Ribosomal_S17 PF00366.18 001309900.1_53722001_3 - 2.4e-27 94.7 0.8 3.9e-27 94.0 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PMEI PF04043.13 001317371.1_53722001_1 - 5.8e-16 59.0 1.7 8.8e-16 58.5 1.7 1.3 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor FLO_LFY PF01698.14 001288057.3_48623001_1 - 1.6e-210 698.9 0.0 1.9e-210 698.7 0.0 1.0 1 0 0 1 1 1 1 Floricaula / Leafy protein CAP_N PF01213.17 001288057.3_48623001_1 - 3.9 6.7 8.0 6.3 6.1 8.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA PF00004.27 001147493.1_53724001_3 - 6.5e-40 136.5 0.0 1.1e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.10 001147493.1_53724001_3 - 7.8e-06 25.2 0.0 1.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.4 001147493.1_53724001_3 - 0.00016 21.8 2.1 0.0036 17.4 0.9 2.8 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.11 001147493.1_53724001_3 - 0.00023 20.1 0.0 0.00038 19.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.12 001147493.1_53724001_3 - 0.00065 19.6 0.0 0.0021 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.4 001147493.1_53724001_3 - 0.00081 19.0 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.4 001147493.1_53724001_3 - 0.00096 19.4 0.1 0.004 17.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.4 001147493.1_53724001_3 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.19 001147493.1_53724001_3 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.15 001147493.1_53724001_3 - 0.002 17.8 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.12 001147493.1_53724001_3 - 0.0022 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.4 001147493.1_53724001_3 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001147493.1_53724001_3 - 0.011 15.8 2.0 0.052 13.6 0.1 2.5 2 1 1 3 3 3 0 AAA domain NACHT PF05729.10 001147493.1_53724001_3 - 0.012 15.4 0.2 0.12 12.1 0.2 2.4 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.24 001147493.1_53724001_3 - 0.015 14.8 0.0 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.20 001147493.1_53724001_3 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.4 001147493.1_53724001_3 - 0.019 15.1 1.2 0.038 14.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.4 001147493.1_53724001_3 - 0.043 13.3 0.8 0.086 12.3 0.1 1.8 3 0 0 3 3 2 0 AAA domain ATPase PF06745.11 001147493.1_53724001_3 - 0.068 12.4 0.5 3 7.0 0.1 2.2 1 1 1 2 2 2 0 KaiC DUF815 PF05673.11 001147493.1_53724001_3 - 0.085 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.14 001147493.1_53724001_3 - 0.088 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.25 001147493.1_53724001_3 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Vps4_C PF09336.8 001147493.1_53724001_3 - 0.13 12.2 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain TsaE PF02367.15 001147493.1_53724001_3 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001147493.1_53724001_3 - 0.15 10.9 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NAM PF02365.13 001158011.1_53723001_2 - 2.2e-20 73.2 0.0 4.2e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein Perm-CXXC PF15629.4 001158011.1_53723001_2 - 0.91 9.7 3.6 1.2 9.3 0.4 2.4 2 0 0 2 2 2 0 Permuted single zf-CXXC unit dsrm PF00035.24 001165724.1_53724001_1 - 8.6e-16 58.3 0.0 5e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif CN_hydrolase PF00795.20 001112112.2_53724001_1 - 1.3e-67 227.7 0.0 1.6e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAS PF03059.14 001112034.2_53723001_1 - 5.6e-131 435.8 0.0 7.7e-131 435.3 0.0 1.1 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_25 PF13649.4 001112034.2_53723001_1 - 0.00016 22.2 0.2 0.0013 19.3 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.4 001112034.2_53723001_1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Rad9 PF04139.11 001156310.2_53724001_3 - 4.3e-63 213.0 0.0 5.3e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.14 001156310.2_53724001_3 - 0.019 13.9 0.0 0.1 11.6 0.0 1.9 1 1 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 Trp_syntA PF00290.18 001254838.2_53723001_3 - 2.9e-95 317.9 0.3 3.5e-95 317.6 0.3 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.19 001254838.2_53723001_3 - 1.4e-05 24.6 0.1 2.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.15 001254838.2_53723001_3 - 0.0084 15.5 0.2 0.016 14.5 0.2 1.4 1 0 0 1 1 1 1 PcrB family ThiG PF05690.12 001254838.2_53723001_3 - 0.0098 15.1 0.1 0.0098 15.1 0.1 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.15 001254838.2_53723001_3 - 0.022 14.0 0.5 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI IGPS PF00218.19 001254838.2_53723001_3 - 0.029 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase NanE PF04131.12 001254838.2_53723001_3 - 0.06 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase BtpA PF03437.13 001254838.2_53723001_3 - 0.061 12.6 0.5 0.2 10.9 0.4 1.8 1 1 1 2 2 2 0 BtpA family Ribul_P_3_epim PF00834.17 001254838.2_53723001_3 - 0.15 11.3 0.2 0.47 9.7 0.1 1.8 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Aldedh PF00171.20 001112589.2_53725001_2 - 1.8e-126 422.3 0.0 2.2e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF793 PF05633.9 001149788.2_53723001_3 - 0.033 13.1 0.2 0.11 11.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF793) Ins134_P3_kin PF05770.9 001112431.2_53724001_2 - 8.3e-138 458.6 0.0 1e-137 458.3 0.0 1.0 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase FBPase PF00316.18 001153987.3_53724001_1 - 7.9e-41 139.5 0.0 1.1e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CbeA_antitoxin PF06154.9 001153987.3_53724001_1 - 0.094 13.1 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A SAP PF02037.25 001153434.2_53725001_2 - 3e-12 45.9 0.6 4.4e-09 35.8 0.7 2.4 2 0 0 2 2 2 2 SAP domain Exo_endo_phos PF03372.21 001153434.2_53725001_2 - 4.1e-12 46.2 0.0 6.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.4 001153434.2_53725001_2 - 0.016 14.9 0.1 0.084 12.6 0.1 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Rho_N PF07498.10 001153434.2_53725001_2 - 0.15 11.9 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain p450 PF00067.20 001143633.2_53724001_1 - 5.8e-64 216.4 0.0 7.8e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S19 PF00203.19 148061.1_53721120_2 - 4.4e-24 84.0 0.1 5.4e-24 83.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Pex14_N PF04695.11 001156541.2_53724001_2 - 7.6e-28 98.0 0.5 7.6e-28 98.0 0.5 3.0 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DNA_methylase PF00145.15 001111507.2_53725001_1 - 1.9e-14 53.6 0.0 2.7e-09 36.7 0.0 2.4 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase UBA PF00627.29 001111507.2_53725001_1 - 4.2e-05 23.2 0.0 0.26 11.1 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain DUF1421 PF07223.9 001111507.2_53725001_1 - 1 9.1 4.0 15 5.2 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1421) UDPGT PF00201.16 001352897.1_53724001_3 - 2e-21 76.3 0.0 2.8e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_4 PF13692.4 001352897.1_53724001_3 - 0.00087 19.6 0.0 0.0059 16.9 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_tran_28_C PF04101.14 001352897.1_53724001_3 - 0.0087 15.9 0.0 0.032 14.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Cupin_3 PF05899.10 001137167.1_53722001_1 - 5.2e-32 109.2 1.2 7.1e-32 108.7 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.10 001137167.1_53722001_1 - 0.00026 20.6 0.0 0.0005 19.7 0.0 1.4 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.9 001137167.1_53722001_1 - 0.0014 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.5 001137167.1_53722001_1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_1 PF00190.20 001137167.1_53722001_1 - 0.03 13.8 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Cupin HATPase_c PF02518.24 001143560.1_53724001_1 - 1.5e-34 118.8 0.0 2.5e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.24 001143560.1_53724001_1 - 1.7e-16 60.8 0.2 3.2e-16 59.9 0.2 1.5 1 0 0 1 1 1 1 GAF domain HisKA PF00512.23 001143560.1_53724001_1 - 3.3e-16 58.9 1.3 3.3e-16 58.9 1.3 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.4 001143560.1_53724001_1 - 1.2e-05 25.5 0.0 0.01 16.0 0.0 2.5 2 0 0 2 2 2 2 GAF domain COX6B PF02297.15 001138001.1_53722001_3 - 6.7e-17 61.4 3.6 1.1e-16 60.6 3.6 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF1631 PF07793.9 001138001.1_53722001_3 - 2.2 6.5 7.7 5.1 5.3 7.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) PSII PF00421.17 001137834.1_53722001_3 - 0.026 13.1 0.1 0.032 12.8 0.1 1.0 1 0 0 1 1 1 0 Photosystem II protein FmdA_AmdA PF03069.13 001143425.1_53724001_3 - 9e-64 215.5 0.0 1.3e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family HMG_box PF00505.17 001112013.1_53722001_1 - 7.1e-22 77.5 3.1 1.1e-21 76.9 3.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001112013.1_53722001_1 - 1.3e-17 63.9 4.2 2.3e-17 63.2 4.2 1.4 1 0 0 1 1 1 1 HMG-box domain Cwf_Cwc_15 PF04889.10 001112013.1_53722001_1 - 0.52 9.9 13.1 0.64 9.6 13.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ANAPC15 PF15243.4 001112013.1_53722001_1 - 8.6 6.7 13.4 13 6.1 13.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RRM_1 PF00076.20 001139311.1_53723001_1 - 4.3e-15 55.2 0.0 7.2e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_1_2 PF00155.19 001138546.1_53724001_1 - 1.5e-53 182.2 0.0 1.7e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001138546.1_53724001_1 - 4.4e-07 29.3 0.0 6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.17 001138546.1_53724001_1 - 6.1e-05 22.0 0.0 9.6e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.18 001138546.1_53724001_1 - 0.00073 18.0 0.0 0.0011 17.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.19 001138546.1_53724001_1 - 0.0078 14.8 0.0 0.12 10.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-III Glyco_hydro_20 PF00728.20 001138546.1_53724001_1 - 0.0087 15.4 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain SET PF00856.26 001111729.1_53723001_3 - 3.9e-14 53.3 0.0 1.1e-13 51.8 0.0 1.7 1 1 0 1 1 1 1 SET domain DUF2062 PF09835.7 001137901.1_53724001_2 - 5.6e-15 55.4 7.2 8.3e-15 54.8 7.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) zf-TRAF PF02176.16 001138159.1_53723001_2 - 9.6e-14 51.7 19.6 3.8e-11 43.4 8.2 2.5 1 1 1 2 2 2 2 TRAF-type zinc finger Sina PF03145.14 001138159.1_53723001_2 - 0.0039 17.1 18.2 0.28 11.0 0.7 3.1 1 1 2 3 3 3 2 Seven in absentia protein family DUF16 PF01519.14 001138159.1_53723001_2 - 0.042 14.2 3.4 0.14 12.5 3.4 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 zf-TRAF_2 PF15965.3 001138159.1_53723001_2 - 0.11 12.8 18.7 0.11 12.9 13.8 2.5 1 1 2 3 3 3 0 TRAF-like zinc-finger TB2_DP1_HVA22 PF03134.17 001138771.1_53723001_2 - 8e-27 92.9 8.7 8e-27 92.9 8.7 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Glyco_trans_4_5 PF16994.3 001136975.1_53724001_1 - 2.1e-44 151.0 0.4 5.4e-44 149.7 0.0 1.9 3 0 0 3 3 3 1 Glycosyl-transferase family 4 Glycos_transf_1 PF00534.18 001136975.1_53724001_1 - 1e-19 70.7 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001136975.1_53724001_1 - 1.8e-16 60.7 0.1 2.8e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001136975.1_53724001_1 - 0.00032 20.9 0.0 0.00082 19.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_5 PF16994.3 001136975.1_53724001_2 - 7e-17 61.4 0.1 1.1e-16 60.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl-transferase family 4 DUF4201 PF13870.4 001147760.1_53724001_2 - 0.0011 18.5 20.6 0.0078 15.7 8.5 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) ATG16 PF08614.9 001147760.1_53724001_2 - 0.0012 19.0 30.4 0.021 14.9 8.1 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.4 001147760.1_53724001_2 - 0.003 17.0 11.5 0.003 17.0 11.5 2.4 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 V-SNARE PF05008.13 001147760.1_53724001_2 - 0.0045 17.2 6.1 0.0045 17.2 6.1 2.8 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus MscS_porin PF12795.5 001147760.1_53724001_2 - 0.0048 16.3 26.1 0.0048 16.3 26.1 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Atg14 PF10186.7 001147760.1_53724001_2 - 0.0094 14.9 28.3 0.0087 15.0 11.5 2.3 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 HrpB7 PF09486.8 001147760.1_53724001_2 - 0.011 16.0 16.1 0.011 16.0 16.1 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Baculo_PEP_C PF04513.10 001147760.1_53724001_2 - 0.013 15.4 2.1 0.013 15.4 2.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Alanine_zipper PF11839.6 001147760.1_53724001_2 - 0.018 15.2 13.8 0.018 15.2 13.8 3.8 2 1 1 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein Tropomyosin PF00261.18 001147760.1_53724001_2 - 0.025 13.8 38.5 0.019 14.2 17.1 2.8 2 1 1 3 3 3 0 Tropomyosin DUF4686 PF15742.3 001147760.1_53724001_2 - 0.042 12.8 29.1 0.077 12.0 29.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Reo_sigmaC PF04582.10 001147760.1_53724001_2 - 0.057 12.7 10.4 0.12 11.6 1.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.17 001147760.1_53724001_2 - 0.16 9.7 16.2 0.33 8.6 15.1 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Filament PF00038.19 001147760.1_53724001_2 - 0.19 11.1 26.0 1.2 8.6 14.9 2.6 1 1 1 2 2 2 0 Intermediate filament protein IncA PF04156.12 001147760.1_53724001_2 - 0.22 11.2 40.4 1.1 8.9 18.1 3.1 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.5 001147760.1_53724001_2 - 0.26 11.3 32.7 5.8 6.9 24.8 2.8 1 1 1 2 2 2 0 Tropomyosin like Spc7 PF08317.9 001147760.1_53724001_2 - 0.32 9.7 34.2 0.16 10.7 13.0 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.13 001147760.1_53724001_2 - 0.43 10.9 31.0 1.5 9.1 26.7 2.8 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.7 001147760.1_53724001_2 - 0.57 9.5 27.5 0.062 12.6 11.9 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 FUSC PF04632.10 001147760.1_53724001_2 - 0.62 8.4 9.1 2.1 6.7 9.0 1.9 1 1 0 1 1 1 0 Fusaric acid resistance protein family Lebercilin PF15619.4 001147760.1_53724001_2 - 0.68 9.4 31.8 0.065 12.7 21.9 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HemX PF04375.12 001147760.1_53724001_2 - 0.94 8.6 29.4 0.44 9.7 5.0 3.3 2 1 1 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Jnk-SapK_ap_N PF09744.7 001147760.1_53724001_2 - 0.96 9.5 32.5 0.21 11.6 11.6 2.9 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 EzrA PF06160.10 001147760.1_53724001_2 - 1.3 7.0 27.4 11 3.9 24.3 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Tup_N PF08581.8 001147760.1_53724001_2 - 1.5 9.0 19.3 2.2 8.5 10.6 2.7 2 0 0 2 2 2 0 Tup N-terminal Transposase_22 PF02994.12 001147760.1_53724001_2 - 1.6 7.4 19.8 3.2 6.4 1.2 2.2 1 1 1 2 2 2 0 L1 transposable element HOOK PF05622.10 001147760.1_53724001_2 - 1.7 6.6 30.3 8.5 4.3 3.3 2.0 1 1 1 2 2 2 0 HOOK protein CHD5 PF04420.12 001147760.1_53724001_2 - 1.9 8.2 12.3 1.1 8.9 8.0 2.6 1 1 1 2 2 2 0 CHD5-like protein DUF4795 PF16043.3 001147760.1_53724001_2 - 2.4 7.6 27.3 1.8 8.0 5.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Tektin PF03148.12 001147760.1_53724001_2 - 2.4 6.7 24.6 1.7 7.2 3.7 2.2 1 1 1 2 2 2 0 Tektin family GAS PF13851.4 001147760.1_53724001_2 - 2.6 7.2 32.4 0.87 8.8 16.9 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.7 001147760.1_53724001_2 - 3.4 6.4 24.3 0.36 9.6 8.5 2.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 MAD PF05557.11 001147760.1_53724001_2 - 3.8 5.6 29.6 36 2.4 29.6 2.0 1 1 0 1 1 1 0 Mitotic checkpoint protein COG5 PF10392.7 001147760.1_53724001_2 - 3.8 7.6 12.7 0.69 9.9 0.2 2.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 SKA1 PF07160.10 001147760.1_53724001_2 - 3.9 7.1 25.9 0.17 11.6 2.9 2.9 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF3584 PF12128.6 001147760.1_53724001_2 - 4.3 4.6 29.5 8.3 3.6 10.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) SlyX PF04102.10 001147760.1_53724001_2 - 4.4 7.9 18.1 60 4.2 7.3 4.2 1 1 2 3 3 3 0 SlyX ApoO PF09769.7 001147760.1_53724001_2 - 4.4 7.2 12.4 7.5 6.4 0.2 4.7 2 2 2 5 5 5 0 Apolipoprotein O PhoU PF01895.17 001147760.1_53724001_2 - 4.5 7.7 15.3 5.4 7.4 2.8 3.0 1 1 2 3 3 3 0 PhoU domain Lectin_N PF03954.12 001147760.1_53724001_2 - 4.6 6.9 15.1 2.3 7.8 0.7 3.5 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain APG6 PF04111.10 001147760.1_53724001_2 - 6.1 6.0 31.3 8.7 5.5 3.6 2.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Nup54 PF13874.4 001147760.1_53724001_2 - 6.1 6.8 18.4 1.4 8.9 10.1 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ADIP PF11559.6 001147760.1_53724001_2 - 6.6 6.7 28.2 45 4.0 8.5 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MPS2 PF17060.3 001147760.1_53724001_2 - 6.6 5.7 19.1 2.3 7.2 1.6 2.3 1 1 1 2 2 2 0 Monopolar spindle protein 2 AAA_13 PF13166.4 001147760.1_53724001_2 - 7.6 4.9 35.3 0.17 10.4 28.2 1.8 2 1 0 2 2 2 0 AAA domain BRE1 PF08647.9 001147760.1_53724001_2 - 9 6.3 34.7 6.5 6.8 10.0 3.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase PRK PF00485.16 001146843.1_53723001_2 - 1.1e-11 44.7 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.4 001146843.1_53723001_2 - 0.0006 20.2 0.0 0.0024 18.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.20 001146843.1_53723001_2 - 0.002 17.1 0.1 0.02 13.8 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.4 001146843.1_53723001_2 - 0.0084 16.4 0.0 0.094 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.10 001146843.1_53723001_2 - 0.0093 15.1 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.4 001146843.1_53723001_2 - 0.029 13.8 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.4 001146843.1_53723001_2 - 0.03 14.6 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.27 001146843.1_53723001_2 - 0.032 14.5 0.1 0.11 12.8 0.1 1.8 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.14 001146843.1_53723001_2 - 0.043 12.7 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.4 001146843.1_53723001_2 - 0.046 13.8 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.4 001146843.1_53723001_2 - 0.066 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.25 001146843.1_53723001_2 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.4 001146843.1_53723001_2 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.12 001146843.1_53723001_2 - 0.18 10.9 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_11 PF13086.4 001146843.1_53723001_2 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Meth_synt_2 PF01717.16 001159041.1_53726001_2 - 1.5e-162 540.3 0.0 1.5e-157 523.8 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.10 001159041.1_53726001_2 - 3e-125 417.8 0.0 1.1e-116 389.7 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain TM1586_NiRdase PF14512.4 001159041.1_53726001_2 - 0.015 14.7 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Putative TM nitroreductase Histone_H2A_C PF16211.3 001196581.1_53722001_2 - 5.4e-19 67.5 1.5 5.4e-19 67.5 1.5 2.2 3 0 0 3 3 3 1 C-terminus of histone H2A Histone PF00125.22 001196581.1_53722001_2 - 4.2e-13 49.7 0.3 8.3e-13 48.7 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001196581.1_53722001_2 - 0.00036 20.6 0.0 0.00069 19.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MatE PF01554.16 001147130.1_53724001_3 - 1.9e-63 212.8 32.3 1.4e-35 122.2 13.2 2.3 2 0 0 2 2 2 2 MatE Antimicrobial21 PF14861.4 001149167.1_53724001_3 - 5.9e-55 182.5 212.7 1.3e-09 37.5 15.3 9.3 9 1 0 10 10 10 7 Plant antimicrobial peptide Vicilin_N PF04702.10 001149167.1_53724001_3 - 0.0065 16.2 51.9 0.0065 16.2 51.9 4.7 1 1 4 5 5 5 4 Vicilin N terminal region Phage_holin_3_6 PF07332.9 001149167.1_53724001_3 - 0.17 11.8 1.2 0.28 11.1 1.2 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III zf-RING_11 PF17123.3 001157992.1_53723001_2 - 6.6e-10 38.4 0.7 1.4e-09 37.4 0.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.4 001157992.1_53723001_2 - 6.5e-09 35.8 8.4 1.5e-08 34.6 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 001157992.1_53723001_2 - 0.00062 19.9 6.0 0.0015 18.6 6.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001157992.1_53723001_2 - 0.0013 18.4 1.8 0.0026 17.4 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Gly-zipper_Omp PF13488.4 001157992.1_53723001_2 - 0.0018 18.1 10.6 0.0018 18.1 10.6 2.2 2 0 0 2 2 2 1 Glycine zipper zf-RING_UBOX PF13445.4 001157992.1_53723001_2 - 0.0019 18.0 6.3 0.004 17.0 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.4 001157992.1_53723001_2 - 0.0022 17.7 7.3 0.0045 16.7 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Gly-zipper_OmpA PF13436.4 001157992.1_53723001_2 - 0.0074 15.9 10.0 0.0074 15.9 10.0 2.3 2 0 0 2 2 2 1 Glycine-zipper domain Gly-zipper_YMGG PF13441.4 001157992.1_53723001_2 - 0.0076 15.8 10.8 0.0076 15.8 10.8 2.2 1 1 1 2 2 2 1 YMGG-like Gly-zipper DUF1269 PF06897.10 001157992.1_53723001_2 - 4.1 7.6 8.1 3.4 7.9 6.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) zf-RING_2 PF13639.4 001176026.1_53723001_1 - 9.6e-13 48.0 5.5 2.4e-12 46.7 5.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001176026.1_53723001_1 - 9.3e-10 37.9 1.5 1.9e-09 37.0 1.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001176026.1_53723001_1 - 4.4e-08 32.7 4.4 8.2e-08 31.8 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001176026.1_53723001_1 - 1.8e-06 28.0 5.4 4.1e-06 26.9 5.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001176026.1_53723001_1 - 0.00011 21.9 2.5 0.00024 20.8 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001176026.1_53723001_1 - 0.00078 19.3 3.8 0.0016 18.3 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001176026.1_53723001_1 - 0.001 18.9 1.7 0.002 17.9 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.4 001176026.1_53723001_1 - 0.0011 18.7 5.3 0.0023 17.6 5.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Gly-zipper_YMGG PF13441.4 001176026.1_53723001_1 - 0.011 15.4 8.6 0.011 15.4 8.6 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper zf-ANAPC11 PF12861.5 001176026.1_53723001_1 - 0.012 15.6 2.0 0.025 14.5 2.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1269 PF06897.10 001176026.1_53723001_1 - 0.024 14.8 0.2 0.05 13.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) zf-C3HC4_3 PF13920.4 001176026.1_53723001_1 - 0.03 14.1 1.8 0.074 12.8 1.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.3 001176026.1_53723001_1 - 0.093 12.2 4.5 0.21 11.1 4.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3040 PF11239.6 001176026.1_53723001_1 - 3.2 7.9 4.4 3.2 8.0 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Gly-zipper_Omp PF13488.4 001176026.1_53723001_1 - 8.6 6.4 20.0 0.28 11.1 11.1 2.3 2 0 0 2 2 2 0 Glycine zipper Glyco_transf_22 PF03901.15 001155353.1_53724001_2 - 2.4e-44 152.1 28.6 3.3e-44 151.6 28.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4413 PF14372.4 001175808.1_53726001_1 - 5.4e-31 106.7 0.1 1.8e-30 105.1 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.12 001175808.1_53726001_1 - 6.7e-21 73.8 0.0 1.9e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.13 001175808.1_53726001_1 - 1.2e-09 37.9 8.9 1.7e-05 24.6 1.9 2.7 2 0 0 2 2 2 2 BED zinc finger DUF2024 PF09630.8 001175808.1_53726001_1 - 0.47 10.2 2.3 3.3 7.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) Histone_H2A_C PF16211.3 001148516.2_53722001_3 - 1.9e-17 62.5 0.4 1.9e-17 62.5 0.4 1.9 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.22 001148516.2_53722001_3 - 1.1e-13 51.6 0.0 1.5e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001148516.2_53722001_3 - 3.5e-05 23.9 0.0 5.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone STT3 PF02516.12 001175249.1_53726001_1 - 2.6e-121 405.8 41.0 2.8e-117 392.5 37.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.4 001175249.1_53726001_1 - 0.00063 19.9 16.5 0.00063 19.9 16.5 3.6 4 1 1 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase UFC1 PF08694.9 001155381.1_53722001_2 - 1.1e-78 262.1 0.0 1.3e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.24 001155381.1_53722001_2 - 0.0074 15.8 0.2 0.034 13.7 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001155381.1_53722001_2 - 0.14 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain PBP PF01161.18 001152104.1_53722001_3 - 2.2e-31 108.8 0.0 2.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF642 PF04862.10 001150173.1_53724001_3 - 7.3e-83 275.9 0.0 6.7e-61 204.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF642) CBM_4_9 PF02018.15 001150173.1_53724001_3 - 0.023 14.8 0.1 0.75 9.9 0.0 2.4 2 1 0 2 2 2 0 Carbohydrate binding domain zf-C2H2_jaz PF12171.6 001153373.1_53722001_3 - 7e-11 42.0 5.1 1.3e-10 41.1 5.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001153373.1_53722001_3 - 4.6e-06 26.7 2.7 4.6e-06 26.7 2.7 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.5 001153373.1_53722001_3 - 0.069 13.4 0.1 0.069 13.4 0.1 1.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Cu_bind_like PF02298.15 001153813.1_53722001_2 - 3.4e-24 84.5 0.0 6.1e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Plastocyanin-like domain SecE PF00584.18 001157439.1_53722001_2 - 3.7e-12 45.9 0.1 5.2e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex P_C PF06640.9 001157439.1_53722001_3 - 7.4 6.6 15.9 10 6.2 15.9 1.1 1 0 0 1 1 1 0 P protein C-terminus zf-DHHC PF01529.18 001147600.1_53723001_3 - 1.2e-39 135.4 6.5 1.2e-39 135.4 6.5 2.3 3 0 0 3 3 3 1 DHHC palmitoyltransferase PGG PF13962.4 001147600.1_53723001_3 - 0.024 14.3 2.4 0.042 13.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function Ilm1 PF10311.7 001147600.1_53723001_3 - 0.054 13.0 0.1 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MitoNEET_N PF10660.7 001147600.1_53723001_3 - 0.29 11.0 2.2 0.84 9.6 2.2 1.7 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus MscS_TM PF12794.5 001147600.1_53723001_3 - 0.87 8.2 7.8 0.25 10.0 0.8 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Cu_amine_oxidN3 PF02728.14 001154485.1_53725001_1 - 0.11 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain COX8 PF02285.13 001154485.1_53725001_1 - 5 6.9 5.6 0.42 10.4 0.3 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII zf-RING_2 PF13639.4 001154485.1_53725001_3 - 6e-13 48.7 5.2 1.5e-12 47.4 5.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001154485.1_53725001_3 - 2.9e-10 39.6 1.6 7.9e-10 38.1 1.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.20 001154485.1_53725001_3 - 2.3e-09 37.1 0.2 4.2e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.4 001154485.1_53725001_3 - 7.3e-07 28.8 4.2 1.8e-06 27.5 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001154485.1_53725001_3 - 7.9e-07 28.7 2.2 2e-06 27.5 2.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001154485.1_53725001_3 - 1.5e-05 25.1 6.4 3.6e-05 23.8 6.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.4 001154485.1_53725001_3 - 4.8e-05 23.1 0.8 0.00038 20.3 0.2 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 001154485.1_53725001_3 - 0.00012 21.8 1.9 0.00034 20.4 1.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001154485.1_53725001_3 - 0.00074 19.2 2.1 0.002 17.8 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001154485.1_53725001_3 - 0.0016 18.2 2.4 0.004 16.8 2.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.5 001154485.1_53725001_3 - 0.031 14.2 1.7 0.069 13.1 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_TL5_C PF14693.4 001148403.1_53723001_2 - 4.1e-18 65.4 0.0 7.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.17 001148403.1_53723001_2 - 6.2e-11 42.5 0.1 9.6e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal L25p family Peptidase_S28 PF05577.10 001156255.1_53724001_2 - 4.9e-74 249.5 1.6 9.7e-74 248.6 1.6 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Ras PF00071.20 001147085.1_53723001_3 - 3.1e-41 140.6 0.1 2.8e-40 137.4 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.11 001147085.1_53723001_3 - 8.7e-20 71.0 0.1 1.1e-12 48.1 0.1 2.5 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001147085.1_53723001_3 - 1.7e-05 24.2 0.0 6.3e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001147085.1_53723001_3 - 0.0023 17.7 0.0 0.007 16.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001147085.1_53723001_3 - 0.0039 17.1 0.1 0.011 15.7 0.1 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.4 001147085.1_53723001_3 - 0.0074 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 001147085.1_53723001_3 - 0.017 15.3 0.0 0.034 14.3 0.0 1.6 1 1 1 2 2 2 0 AAA domain Septin PF00735.16 001147085.1_53723001_3 - 0.029 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Septin cobW PF02492.17 001147085.1_53723001_3 - 0.033 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.4 001147085.1_53723001_3 - 0.042 13.4 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.16 001147085.1_53723001_3 - 0.077 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.7 001147085.1_53723001_3 - 0.078 12.6 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Flo11 PF10182.7 001147085.1_53723001_3 - 0.079 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Flo11 domain RNA_helicase PF00910.20 001147085.1_53723001_3 - 0.11 12.8 0.1 0.25 11.6 0.1 1.7 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.10 001147085.1_53723001_3 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.9 001147085.1_53723001_3 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein TMEM70 PF06979.10 001152752.1_53724001_2 - 4.2e-30 104.7 0.1 6.8e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex PC-Esterase PF13839.4 001147067.1_53724001_3 - 7.2e-87 291.6 0.1 8.8e-87 291.3 0.1 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.4 001147067.1_53724001_3 - 5.2e-23 81.0 3.6 5.2e-23 81.0 3.6 2.1 2 0 0 2 2 2 1 PMR5 N terminal Domain IATP PF04568.10 001150007.2_53722001_2 - 0.0078 16.5 3.1 0.0078 16.5 3.1 2.4 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP Fez1 PF06818.13 001155634.1_53724001_3 - 0.035 14.4 39.5 0.42 10.9 22.1 2.3 1 1 1 2 2 2 0 Fez1 Reo_sigmaC PF04582.10 001155634.1_53724001_3 - 0.85 8.8 19.4 3 7.0 11.9 2.6 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Golgin_A5 PF09787.7 001155634.1_53724001_3 - 2.4 7.4 44.9 0.42 9.9 13.0 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.7 001155634.1_53724001_3 - 9.8 6.2 43.2 4.5 7.3 12.9 3.1 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Aldose_epim PF01263.18 001176349.1_53723001_1 - 3.9e-81 272.5 0.0 4.8e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase p450 PF00067.20 001288400.1_48623001_1 - 3.2e-21 75.5 0.7 6.3e-20 71.2 0.2 2.3 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_32N PF00251.18 001288064.1_48624001_1 - 2e-107 359.2 5.3 2.6e-107 358.8 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.10 001288064.1_48624001_1 - 2.8e-13 50.3 0.0 6.8e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF3357 PF11837.6 001288064.1_48624001_1 - 2.9e-09 37.2 0.1 7.4e-09 35.9 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3357) IF4E PF01652.16 001288431.1_48622001_1 - 3.4e-51 173.0 1.5 4.1e-51 172.8 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TCP PF03634.11 001288104.1_48623001_1 - 1.8e-43 148.7 5.4 1.8e-43 148.7 5.4 2.1 2 0 0 2 2 2 1 TCP family transcription factor FAD_binding_4 PF01565.21 001288495.1_48624001_1 - 1.3e-14 54.0 0.1 2e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Phage_holin_2_4 PF16082.3 001288495.1_48624001_1 - 0.12 12.1 0.1 0.41 10.4 0.1 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF5090 PF17009.3 001288495.1_48624001_1 - 0.27 11.0 0.8 0.53 10.1 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DXP_synthase_N PF13292.4 001288201.1_48625001_1 - 1.9e-112 374.8 0.0 3e-112 374.1 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.22 001288201.1_48625001_1 - 5.3e-44 149.9 0.9 7.8e-44 149.3 0.2 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 001288201.1_48625001_1 - 3.9e-31 107.4 0.0 7.6e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.19 001288201.1_48625001_1 - 3.9e-06 26.6 1.3 0.00028 20.6 0.4 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.18 001288201.1_48625001_1 - 1.3e-05 24.2 0.0 2.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.19 001288201.1_48625001_1 - 0.00038 19.4 1.2 0.02 13.8 0.5 2.8 2 1 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain RRM_1 PF00076.20 001287847.1_48624001_3 - 2.8e-27 94.2 0.0 4.8e-13 48.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001287847.1_48624001_3 - 3.6e-09 36.5 0.1 7.2e-05 22.7 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif Cut8 PF08559.8 001287847.1_48624001_3 - 0.015 14.7 0.1 0.015 14.7 0.1 1.8 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein BUD22 PF09073.8 001287847.1_48624001_3 - 1.4 8.0 21.4 2.6 7.2 21.4 1.4 1 0 0 1 1 1 0 BUD22 PBP PF01161.18 001287968.1_48622001_1 - 7.3e-15 55.3 0.0 8.8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Arm PF00514.21 001288176.1_48625001_2 - 6e-22 76.8 0.2 2.4e-07 30.4 0.0 5.6 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat U-box PF04564.13 001288176.1_48625001_2 - 1.6e-20 72.9 0.0 2.8e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain Arm_2 PF04826.11 001288176.1_48625001_2 - 0.00016 21.1 0.0 0.0067 15.8 0.0 2.3 1 1 0 1 1 1 1 Armadillo-like zf-Nse PF11789.6 001288176.1_48625001_2 - 0.0023 17.6 0.1 0.0051 16.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.3 001288176.1_48625001_2 - 0.0095 15.9 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_4 PF15227.4 001288176.1_48625001_2 - 0.074 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HEAT_2 PF13646.4 001288176.1_48625001_2 - 1.4 9.3 12.6 11 6.3 0.2 3.6 1 1 1 3 3 3 0 HEAT repeats POX PF07526.9 001287992.1_48626001_1 - 4.4e-48 163.2 4.5 4.4e-48 163.2 4.5 2.6 3 1 0 3 3 3 1 Associated with HOX Homeobox_KN PF05920.9 001287992.1_48626001_1 - 3e-18 65.3 1.6 3.8e-18 65.0 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.27 001287992.1_48626001_1 - 2.9e-07 30.1 0.1 9.9e-07 28.4 0.1 1.9 1 0 0 1 1 1 1 Homeobox domain CBFD_NFYB_HMF PF00808.21 001316100.1_06922001_1 - 2.5e-26 91.6 0.3 3.4e-26 91.2 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001316100.1_06922001_1 - 4.8e-05 23.6 0.1 6.3e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.14 001316100.1_06922001_1 - 0.00063 19.6 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.4 001316100.1_06922001_1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.11 001316100.1_06922001_1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated XS PF03468.12 001318684.1_48624001_1 - 2.3e-33 114.7 0.0 2.3e-33 114.7 0.0 2.6 2 1 0 2 2 2 1 XS domain zf-XS PF03470.12 001318684.1_48624001_1 - 1.6e-08 34.5 0.1 8.9e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 XS zinc finger domain p450 PF00067.20 001318693.1_48624001_1 - 9.5e-117 390.4 0.0 1.1e-116 390.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AP2 PF00847.18 001318553.1_48622001_1 - 4.8e-14 52.2 2.7 9.5e-14 51.3 2.7 1.5 1 0 0 1 1 1 1 AP2 domain SAE2 PF08573.8 001323612.1_53722001_2 - 0.028 15.4 0.2 0.038 15.0 0.2 1.2 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus p450 PF00067.20 001318702.1_48624001_1 - 9.2e-117 390.5 0.0 1e-116 390.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Flavi_M PF01004.17 001318702.1_48624001_1 - 0.18 11.5 0.3 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M LEA_1 PF03760.13 001157274.2_53722001_2 - 1.2e-17 64.1 24.0 1.2e-17 64.1 24.0 1.9 2 0 0 2 2 2 1 Late embryogenesis abundant (LEA) group 1 Cys_Met_Meta_PP PF01053.18 001318674.2_48624001_2 - 7.9e-139 462.3 0.0 9.9e-139 462.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.17 001318674.2_48624001_2 - 3.5e-05 22.8 0.0 0.00031 19.7 0.0 2.2 3 0 0 3 3 3 1 Aminotransferase class-V Aminotran_1_2 PF00155.19 001318674.2_48624001_2 - 0.00019 20.6 0.0 0.00042 19.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001318674.2_48624001_2 - 0.0054 15.9 0.1 0.019 14.2 0.1 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.11 001318674.2_48624001_2 - 0.0097 14.8 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 1 L-seryl-tRNA selenium transferase Aa_trans PF01490.16 001318651.2_48624001_3 - 1.3e-116 389.6 27.9 1.5e-116 389.3 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UQ_con PF00179.24 001347211.1_53723001_3 - 9e-20 70.6 0.0 1.4e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001347211.1_53723001_3 - 0.087 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy PF03171.18 001288220.2_48623001_3 - 4.6e-23 81.5 0.0 9e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001288220.2_48623001_3 - 8.7e-15 55.4 0.0 2e-14 54.2 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pirin_C PF05726.11 001326386.1_53723001_3 - 3.9e-34 117.0 0.0 9.5e-33 112.5 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.14 001326386.1_53723001_3 - 2.8e-33 114.0 0.3 4.8e-33 113.2 0.3 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.9 001326386.1_53723001_3 - 0.00012 21.6 3.6 0.038 13.6 0.6 2.8 2 1 0 2 2 2 2 Cupin domain EGF_MSP1_1 PF12946.5 144518.1_53723120_3 - 0.03 14.3 0.4 0.075 13.0 0.4 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 CaATP_NAI PF12515.6 145577.1_53722120_1 - 4e-20 71.0 0.5 6.6e-20 70.3 0.5 1.4 1 0 0 1 1 1 1 Ca2+-ATPase N terminal autoinhibitory domain Cation_ATPase_N PF00690.24 145577.1_53722120_3 - 0.042 13.4 0.1 0.058 12.9 0.1 1.2 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Dynamin_M PF01031.18 001352973.1_53727001_1 - 3.5e-103 344.6 0.0 5.4e-103 344.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.21 001352973.1_53727001_1 - 4.9e-56 189.3 0.0 1e-55 188.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.16 001352973.1_53727001_1 - 5.2e-28 96.9 3.6 1.4e-27 95.5 3.6 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.21 001352973.1_53727001_1 - 1.3e-05 25.1 0.0 4e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.4 001352973.1_53727001_1 - 0.0031 17.8 0.1 0.12 12.6 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_15 PF13175.4 001352973.1_53727001_1 - 0.0033 17.0 0.2 0.89 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain GH3 PF03321.11 001153365.2_53725001_1 - 3.6e-200 666.2 0.0 4.2e-200 666.0 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter CRA_rpt PF07046.9 001153365.2_53725001_1 - 0.048 13.7 1.6 3.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat bHLH-MYC_N PF14215.4 001352976.1_53725001_2 - 4.8e-19 69.1 0.1 2.3e-11 44.1 0.0 2.4 1 1 1 2 2 2 2 bHLH-MYC and R2R3-MYB transcription factors N-terminal GAF_2 PF13185.4 001352976.1_53725001_2 - 0.018 15.2 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 GAF domain FA_hydroxylase PF04116.11 001155667.2_53723001_3 - 7.8e-15 55.3 14.7 1.3e-14 54.5 14.7 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.11 001155667.2_53723001_3 - 0.021 14.9 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Pkinase PF00069.23 001353172.1_53724001_2 - 1.1e-74 250.9 0.0 1.6e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001353172.1_53724001_2 - 8.5e-30 103.8 0.0 1.4e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001353172.1_53724001_2 - 0.0094 15.2 0.0 0.026 13.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.9 001353172.1_53724001_2 - 0.19 10.6 0.1 0.28 10.1 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 AA_permease_2 PF13520.4 001353169.1_53724001_1 - 4.9e-43 147.4 43.3 6.6e-43 147.0 43.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.19 001353169.1_53724001_1 - 5.2e-33 114.2 38.6 5.2e-33 114.2 38.6 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.4 001353169.1_53724001_1 - 3.8e-15 55.6 3.2 3.8e-15 55.6 3.2 3.5 3 0 0 3 3 3 1 C-terminus of AA_permease Spore_permease PF03845.11 001353169.1_53724001_1 - 0.73 8.5 20.2 0.24 10.1 10.4 2.9 2 1 0 2 2 2 0 Spore germination protein DUF2970 PF11174.6 001353169.1_53724001_1 - 2.2 8.0 0.0 2.2 8.0 0.0 5.0 7 0 0 7 7 7 0 Protein of unknown function (DUF2970) PPR PF01535.18 001154364.2_53725001_2 - 4.4e-28 95.4 1.4 8.6e-06 25.5 0.0 8.6 8 0 0 8 8 8 5 PPR repeat DYW_deaminase PF14432.4 001154364.2_53725001_2 - 9e-24 83.6 0.1 2.1e-22 79.2 0.2 2.5 2 1 0 2 2 2 1 DYW family of nucleic acid deaminases PPR_2 PF13041.4 001154364.2_53725001_2 - 6.6e-20 70.9 0.0 9e-09 35.3 0.0 6.2 4 1 3 7 7 7 4 PPR repeat family PPR_1 PF12854.5 001154364.2_53725001_2 - 3.8e-14 52.0 0.0 0.0037 16.8 0.0 5.3 4 1 1 5 5 5 3 PPR repeat PPR_3 PF13812.4 001154364.2_53725001_2 - 1.6e-08 34.3 0.0 0.0063 16.4 0.0 4.6 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.2 001154364.2_53725001_2 - 5.3e-05 22.6 0.3 0.033 13.4 0.0 3.2 1 1 1 3 3 3 1 Pentacotripeptide-repeat region of PROPR TPR_19 PF14559.4 001154364.2_53725001_2 - 0.00025 21.3 0.2 1.3 9.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.4 001154364.2_53725001_2 - 0.00094 19.3 0.0 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.4 001154364.2_53725001_2 - 0.0012 19.4 0.2 1.8 9.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.4 001154364.2_53725001_2 - 0.013 16.1 2.5 7.9 7.5 0.0 5.2 6 1 0 6 6 6 0 Tetratricopeptide repeat GST_N_3 PF13417.4 001154287.2_53722001_3 - 5.5e-17 61.8 0.0 1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001154287.2_53722001_3 - 1.4e-14 54.0 0.0 2.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001154287.2_53722001_3 - 1.1e-11 44.7 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001154287.2_53722001_3 - 3.4e-09 36.4 0.9 6.1e-09 35.6 0.9 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001154287.2_53722001_3 - 2e-08 34.2 0.1 3.8e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 001154287.2_53722001_3 - 7.1e-05 23.4 0.0 0.00024 21.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.7 001154287.2_53722001_3 - 0.0064 16.6 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.4 001154287.2_53722001_3 - 0.023 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TPR_2 PF07719.15 001154101.3_53726001_2 - 2.9e-28 95.5 13.6 0.0014 18.4 1.6 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.26 001154101.3_53726001_2 - 1.6e-24 84.5 7.1 0.00029 20.4 0.0 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.4 001154101.3_53726001_2 - 3.6e-22 77.6 2.3 4e-05 23.1 0.3 6.8 3 2 4 7 7 7 4 TPR repeat TPR_8 PF13181.4 001154101.3_53726001_2 - 1.3e-19 68.6 5.2 0.037 14.1 0.1 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.4 001154101.3_53726001_2 - 8.3e-18 63.3 0.3 0.044 14.1 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.4 001154101.3_53726001_2 - 1.1e-16 61.1 31.2 1.6e-07 31.8 0.7 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.4 001154101.3_53726001_2 - 1.8e-15 57.0 10.8 6e-08 33.0 0.1 4.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.4 001154101.3_53726001_2 - 5.6e-14 51.5 20.4 0.0047 17.5 0.1 8.0 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.4 001154101.3_53726001_2 - 1e-12 48.0 20.3 0.002 18.2 1.0 5.6 2 1 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.4 001154101.3_53726001_2 - 2.2e-07 30.3 5.3 0.38 10.8 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.4 001154101.3_53726001_2 - 3.7e-07 30.1 17.8 0.0052 16.8 0.1 4.9 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_10 PF13374.4 001154101.3_53726001_2 - 2.2e-06 27.2 22.3 1.6 8.6 0.4 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat EF-hand_1 PF00036.30 001154101.3_53726001_2 - 2.4e-06 26.5 0.5 0.00015 20.9 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.4 001154101.3_53726001_2 - 1.7e-05 24.0 0.2 0.00038 19.7 0.1 2.6 2 0 0 2 2 2 1 EF hand TPR_6 PF13174.4 001154101.3_53726001_2 - 5e-05 23.5 10.8 0.43 11.2 0.0 6.3 7 0 0 7 7 5 1 Tetratricopeptide repeat EF-hand_7 PF13499.4 001154101.3_53726001_2 - 0.00015 22.0 0.0 0.0016 18.8 0.0 2.6 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_6 PF13405.4 001154101.3_53726001_2 - 0.00016 21.2 0.0 0.002 17.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain ANAPC3 PF12895.5 001154101.3_53726001_2 - 0.00041 20.4 3.5 8.1 6.6 0.1 3.8 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 EF-hand_8 PF13833.4 001154101.3_53726001_2 - 0.00086 18.9 1.2 0.043 13.5 0.0 3.5 4 0 0 4 4 3 1 EF-hand domain pair TPR_20 PF14561.4 001154101.3_53726001_2 - 0.0021 18.2 5.2 27 5.1 0.1 4.3 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.10 001154101.3_53726001_2 - 0.0035 17.2 0.8 3.8 7.4 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF627) YfdX PF10938.6 001154101.3_53726001_2 - 0.016 15.0 1.4 0.041 13.7 0.3 2.1 1 1 1 2 2 2 0 YfdX protein BTAD PF03704.15 001154101.3_53726001_2 - 0.034 14.4 11.7 0.75 10.1 0.5 3.3 2 1 1 3 3 3 0 Bacterial transcriptional activator domain DUF3856 PF12968.5 001154101.3_53726001_2 - 0.038 13.9 1.9 14 5.6 0.0 4.0 3 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.12 001154101.3_53726001_2 - 0.049 14.1 14.7 0.46 11.1 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.7 001154101.3_53726001_2 - 1.5 8.4 6.0 9.2 5.8 0.0 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat-like domain zf-U1 PF06220.10 001353228.1_53722001_2 - 8e-11 41.4 0.6 1.4e-10 40.6 0.6 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-CCCH PF00642.22 001353228.1_53722001_2 - 8.7e-07 28.6 6.3 1.5e-06 27.8 6.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.6 001353228.1_53722001_2 - 0.011 15.8 5.2 0.035 14.3 5.2 1.8 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Torus PF16131.3 001353228.1_53722001_2 - 0.019 15.5 3.4 0.026 15.1 2.5 1.6 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.4 001353228.1_53722001_2 - 0.11 12.9 4.4 0.18 12.2 4.4 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PCI PF01399.25 001155245.2_53724001_3 - 3e-14 53.3 0.8 5.8e-14 52.4 0.8 1.5 1 0 0 1 1 1 1 PCI domain ATP-synt_F PF01990.15 001156371.2_53722001_1 - 2.3e-30 104.6 0.2 3.1e-30 104.2 0.2 1.2 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Rad21_Rec8_N PF04825.11 001156371.2_53722001_1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Histone PF00125.22 001137945.2_53722001_3 - 2.3e-54 183.2 2.1 2.8e-54 182.9 2.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001137945.2_53722001_3 - 0.00092 19.2 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.4 001137945.2_53722001_3 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.13 001137945.2_53722001_3 - 0.032 14.2 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.21 001137945.2_53722001_3 - 0.041 14.1 0.1 0.08 13.1 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.3 001137945.2_53722001_3 - 0.052 14.0 1.4 0.089 13.3 1.4 1.3 1 0 0 1 1 1 0 PCNA-associated factor Lzipper-MIP1 PF14389.4 001353342.1_53726001_2 - 2.6e-22 78.7 1.5 5.1e-22 77.8 1.5 1.4 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DUF547 PF04784.12 001353342.1_53726001_2 - 1e-11 44.8 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Pro_isomerase PF00160.19 148412.1_53722120_3 - 5.1e-34 117.7 0.1 6.3e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.19 148408.1_53722120_2 - 2.2e-17 63.6 0.1 2.9e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mo-co_dimer PF03404.14 148411.1_53722120_2 - 1.1e-21 77.2 0.7 1.4e-21 76.9 0.7 1.1 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.18 148411.1_53722120_2 - 0.18 11.8 1.7 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF1644 PF07800.10 001138399.2_53724001_3 - 9.1e-62 207.9 5.4 1.4e-61 207.3 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) DUF1076 PF06416.10 001138399.2_53724001_3 - 0.026 14.3 0.1 0.069 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1076) zf-C3HC4_3 PF13920.4 001138399.2_53724001_3 - 0.054 13.2 9.9 0.38 10.5 3.4 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Tristanin_u2 PF16638.3 001138399.2_53724001_3 - 2.2 9.0 6.8 1 10.0 3.6 1.9 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers 2OG-FeII_Oxy PF03171.18 001158186.2_53723001_2 - 3.5e-28 97.9 0.0 5.9e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001158186.2_53723001_2 - 4.8e-07 30.4 0.0 9.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Vps55 PF04133.12 148421.1_53722120_3 - 9.7e-11 41.5 0.6 1.6e-10 40.8 0.6 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Dimer_Tnp_hAT PF05699.12 148420.1_53724120_1 - 1.3e-10 40.7 0.0 4.5e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ARD PF03079.12 148416.1_53721120_3 - 3e-47 160.6 0.1 3.7e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.9 148416.1_53721120_3 - 2.9e-10 39.6 0.0 4.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.17 148416.1_53721120_3 - 7.3e-09 35.5 0.0 1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.20 148416.1_53721120_3 - 0.00044 19.7 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.10 148416.1_53721120_3 - 0.0088 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.5 148416.1_53721120_3 - 0.012 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Cupin DUF2096 PF09869.7 148416.1_53721120_3 - 0.018 15.0 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Cupin_8 PF13621.4 148416.1_53721120_3 - 0.021 14.5 0.0 0.025 14.2 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain Cupin_3 PF05899.10 148416.1_53721120_3 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) tify PF06200.12 148415.1_53722120_3 - 3e-16 58.3 0.0 5.3e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 tify domain Trp_syntA PF00290.18 001111749.1_53723001_1 - 1.2e-96 322.4 0.0 1.5e-96 322.1 0.0 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.19 001111749.1_53723001_1 - 2.3e-07 30.4 0.0 4.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.15 001111749.1_53723001_1 - 0.00017 21.0 0.3 0.0011 18.4 0.1 2.1 2 1 0 2 2 2 1 PcrB family FMN_dh PF01070.16 001111749.1_53723001_1 - 0.0042 16.0 0.1 0.006 15.5 0.1 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.12 001111749.1_53723001_1 - 0.0047 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.15 001111749.1_53723001_1 - 0.0054 16.0 0.0 0.015 14.5 0.0 1.8 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI BtpA PF03437.13 001111749.1_53723001_1 - 0.0065 15.8 0.3 0.033 13.5 0.1 2.2 3 0 0 3 3 3 1 BtpA family Ribul_P_3_epim PF00834.17 001111749.1_53723001_1 - 0.012 14.9 0.1 0.024 13.9 0.1 1.5 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family NanE PF04131.12 001111749.1_53723001_1 - 0.012 14.6 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.19 001111749.1_53723001_1 - 0.014 14.5 0.0 0.056 12.5 0.0 1.9 1 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase Pribosyltran PF00156.25 001111749.1_53723001_1 - 0.043 13.2 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosyl transferase domain SBF PF01758.14 001165445.1_53724001_3 - 7.8e-40 136.5 13.3 7.8e-40 136.5 13.3 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family Remorin_C PF03763.11 001158231.2_53722001_3 - 5.6e-28 96.8 23.8 9.8e-28 96.1 23.8 1.4 1 0 0 1 1 1 1 Remorin, C-terminal region Remorin_N PF03766.11 001158231.2_53722001_3 - 1.8e-12 46.9 5.3 4.4e-12 45.7 5.3 1.7 1 0 0 1 1 1 1 Remorin, N-terminal region Adeno_PV PF03910.11 001158231.2_53722001_3 - 0.0053 15.4 0.9 0.0079 14.8 0.9 1.2 1 0 0 1 1 1 1 Adenovirus minor core protein PV OmpH PF03938.12 001158231.2_53722001_3 - 0.27 11.1 9.5 0.47 10.3 9.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2681 PF10883.6 001158231.2_53722001_3 - 0.61 10.4 6.2 1.2 9.5 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Rep_fac-A_C PF08646.8 001176029.2_53725001_3 - 5.8e-48 162.2 2.1 9.1e-48 161.6 2.1 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.3 001176029.2_53725001_3 - 3.2e-32 110.2 0.4 7.7e-32 109.0 0.4 1.7 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.10 001176029.2_53725001_3 - 1.8e-26 92.0 0.0 4.8e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.23 001176029.2_53725001_3 - 5.2e-12 45.5 0.6 1.2e-08 34.7 0.0 3.4 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain zf-DHHC PF01529.18 001353407.1_53726001_3 - 3.3e-31 108.0 5.0 3.3e-31 108.0 5.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spiralin PF05215.11 001353407.1_53726001_3 - 0.15 11.2 0.2 0.23 10.6 0.2 1.1 1 0 0 1 1 1 0 Spiralin TcpE PF12648.5 001353407.1_53726001_3 - 3.8 8.0 6.6 10 6.6 3.7 2.4 2 0 0 2 2 2 0 TcpE family Transglut_core3 PF13471.4 001176314.2_53722001_3 - 0.026 14.3 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Transglutaminase-like superfamily HCO3_cotransp PF00955.19 001174274.1_53726001_2 - 1.6e-80 271.3 3.4 7.3e-34 117.4 0.9 3.1 2 1 1 3 3 3 3 HCO3- transporter family Baculo_PEP_C PF04513.10 001174274.1_53726001_2 - 0.16 11.9 0.5 0.33 10.9 0.5 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COX4_pro_2 PF07835.10 001174274.1_53726001_2 - 3.3 7.7 5.0 7.6 6.6 5.0 1.6 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV B_lectin PF01453.22 001143356.1_53723001_3 - 0.00046 20.0 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 D-mannose binding lectin HPIH PF13323.4 001143356.1_53723001_3 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain with HPIH motif Glyco_hydro_28 PF00295.15 001148122.3_53723001_2 - 3.3e-93 312.2 16.5 4.3e-93 311.8 16.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.5 001148122.3_53723001_2 - 1.3e-07 31.6 13.1 2.9e-07 30.5 10.7 2.5 1 1 0 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.4 001148122.3_53723001_2 - 2.3e-07 30.7 8.5 2.3e-07 30.7 8.5 2.8 2 1 0 3 3 3 1 Right handed beta helix region NosD PF05048.11 001148122.3_53723001_2 - 0.00056 19.1 3.3 0.0013 17.9 3.3 1.6 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF4654 PF15547.4 001148122.3_53723001_2 - 0.18 12.1 2.4 0.46 10.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4654) Thioredoxin PF00085.18 001138720.1_53722001_2 - 1e-24 86.3 0.2 1.3e-24 85.9 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.4 001138720.1_53722001_2 - 2.3e-05 24.4 0.2 4.2e-05 23.5 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.4 001138720.1_53722001_2 - 0.00048 20.4 0.1 0.0075 16.6 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.4 001138720.1_53722001_2 - 0.013 15.2 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin DIM1 PF02966.14 001138720.1_53722001_2 - 0.018 14.7 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_8 PF13905.4 001138720.1_53722001_2 - 0.045 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like His_Phos_1 PF00300.20 001136684.2_53723001_1 - 3.5e-11 43.1 0.0 6e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PAM2 PF07145.13 001353542.1_53722001_2 - 0.0068 15.9 0.3 0.015 14.8 0.3 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Ferritin PF00210.22 001353542.1_53722001_2 - 0.037 13.8 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like domain PMEI PF04043.13 001148152.2_53722001_1 - 3.7e-15 56.4 0.2 4.7e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Glu_cyclase_2 PF05096.10 001318686.2_48623001_3 - 4.7e-91 304.5 0.2 6e-91 304.2 0.2 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase SGL PF08450.10 001318686.2_48623001_3 - 0.0022 17.5 0.1 7 6.0 0.0 3.0 3 0 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.4 001318686.2_48623001_3 - 0.06 13.7 0.1 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain PLD_C PF12357.6 001353614.1_53726001_2 - 5.3e-30 103.0 0.0 1e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D C terminal C2 PF00168.28 001353614.1_53726001_2 - 3.5e-25 88.1 0.0 1.5e-24 86.1 0.0 2.1 2 0 0 2 2 2 1 C2 domain PLDc PF00614.20 001353614.1_53726001_2 - 3.3e-16 58.6 1.4 3.4e-07 30.0 0.1 3.4 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.4 001353614.1_53726001_2 - 3.7e-11 42.9 0.2 2.1e-07 30.7 0.1 3.2 2 1 0 2 2 2 2 PLD-like domain AP2 PF00847.18 001148496.2_53723001_1 - 7.8e-14 51.5 0.6 1.6e-13 50.5 0.6 1.6 1 0 0 1 1 1 1 AP2 domain DD_K PF12121.6 001148496.2_53723001_3 - 0.81 9.7 3.9 3 7.9 3.9 2.0 1 0 0 1 1 1 0 Dermaseptin Pyridoxal_deC PF00282.17 001148740.2_53724001_1 - 1.6e-106 356.0 0.0 1.9e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.17 001148740.2_53724001_1 - 0.0033 16.3 0.0 0.011 14.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.19 001148740.2_53724001_1 - 0.0047 16.0 0.0 0.0073 15.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001148740.2_53724001_1 - 0.0059 15.8 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase IQ PF00612.25 148461.1_53723120_1 - 5e-08 31.9 8.4 0.00048 19.6 2.8 2.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif Ribosomal_L10 PF00466.18 001148890.1_53722001_2 - 4e-21 74.9 0.0 5.9e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 HCMVantigenic_N PF12154.6 001148890.1_53722001_3 - 1.9 8.5 6.1 1.7 8.7 4.0 2.1 1 1 1 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV KH_1 PF00013.27 001353619.1_53723001_2 - 0.00055 19.6 0.2 0.001 18.7 0.2 1.4 1 0 0 1 1 1 1 KH domain Abhydrolase_3 PF07859.11 001149305.2_53725001_3 - 6.3e-33 114.3 7.6 1e-17 64.6 0.0 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.26 001149305.2_53725001_3 - 0.0011 17.9 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family IncA PF04156.12 001148979.2_53722001_3 - 0.013 15.1 0.0 0.013 15.1 0.0 1.4 2 0 0 2 2 2 0 IncA protein NBP1 PF08537.8 001148979.2_53722001_3 - 0.026 13.8 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF3293 PF11697.6 001148979.2_53722001_3 - 0.028 14.8 1.2 0.057 13.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) Cnn_1N PF07989.9 001148979.2_53722001_3 - 0.29 11.1 1.9 0.45 10.5 1.1 1.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 MCC-bdg_PDZ PF10506.7 001148979.2_53722001_3 - 0.63 10.0 8.0 2.4 8.1 7.0 2.0 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ZapB PF06005.10 001148979.2_53722001_3 - 1.5 9.2 5.9 2.7 8.4 5.9 1.5 1 1 0 1 1 1 0 Cell division protein ZapB UDPGT PF00201.16 001148910.2_53724001_1 - 3.1e-24 85.5 0.0 5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.18 001148910.2_53724001_1 - 0.099 12.6 0.2 0.3 11.0 0.1 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain RIP PF00161.17 001111495.1_53722001_2 - 1.8e-63 213.6 0.0 2.2e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Ribosome inactivating protein DUF3839 PF12943.5 001111495.1_53722001_2 - 0.036 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) NAM PF02365.13 001147881.2_53723001_2 - 1.9e-10 41.3 0.0 9e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 No apical meristem (NAM) protein Lung_7-TM_R PF06814.11 001147879.2_53724001_2 - 7.5e-49 166.4 9.4 1e-48 165.9 9.4 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.7 001147879.2_53724001_2 - 9.5e-06 25.1 7.1 1.5e-05 24.4 6.3 1.6 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain SPX PF03105.17 001150624.2_53722001_3 - 0.025 14.4 4.7 0.032 14.1 4.7 1.1 1 0 0 1 1 1 0 SPX domain HSBP1 PF06825.10 001150624.2_53722001_3 - 2.3 8.1 6.1 0.22 11.3 0.6 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 zf-FLZ PF04570.12 001149127.1_53722001_1 - 3.1e-20 71.3 0.3 5.4e-20 70.5 0.3 1.4 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 DUF688 PF05097.10 001149528.2_53723001_2 - 0.0011 18.0 0.8 0.0011 18.0 0.8 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF688) Dehydrin PF00257.17 001149528.2_53723001_2 - 0.0013 19.1 0.1 0.0013 19.1 0.1 3.0 3 1 0 3 3 3 1 Dehydrin Apt1 PF10351.7 001149528.2_53723001_2 - 0.12 11.1 5.8 0.13 11.0 5.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAF1-p150_C2 PF15539.4 001149528.2_53723001_2 - 0.69 9.2 5.5 1.4 8.2 5.5 1.5 1 1 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Macoilin PF09726.7 001149528.2_53723001_2 - 0.82 8.0 5.7 0.99 7.7 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SPX PF03105.17 001149528.2_53723001_2 - 1.2 8.9 8.8 1.7 8.4 8.8 1.2 1 0 0 1 1 1 0 SPX domain Porin_3 PF01459.20 148506.1_53723120_2 - 2.6e-13 49.9 0.1 3.6e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin UL11 PF11094.6 148513.1_53722120_2 - 1.7 8.5 5.8 3.7 7.4 5.8 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein PPR PF01535.18 148530.1_53724120_1 - 0.04 14.1 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 PPR repeat DUF1645 PF07816.9 001149478.2_53722001_1 - 6.5e-05 23.5 2.5 0.00019 21.9 2.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1645) BC10 PF06726.10 001149574.1_53722001_1 - 0.31 11.2 3.9 2.2 8.4 1.2 2.4 1 1 1 2 2 2 0 Bladder cancer-related protein BC10 Fibrinogen_BP PF08017.9 001149574.1_53722001_3 - 0.019 13.3 1.7 0.025 12.9 1.7 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein Strep_pep PF14404.4 001149574.1_53722001_3 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species DUF4033 PF13225.4 001149574.1_53722001_3 - 0.25 11.2 12.8 15 5.5 0.3 4.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4033) DUF538 PF04398.10 001150370.2_53722001_1 - 7.2e-34 116.5 0.0 9.5e-34 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF538 DUF1616 PF07760.9 001150905.2_53722001_3 - 0.075 12.3 0.4 0.12 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) HTH_IclR PF09339.8 001196265.2_53725001_1 - 0.26 11.0 3.8 0.23 11.1 2.4 1.6 1 1 0 1 1 1 0 IclR helix-turn-helix domain Rhodanese PF00581.18 001196265.2_53725001_2 - 2.8e-08 34.1 0.0 8.6e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Glucosamine_iso PF01182.18 001158484.2_53723001_2 - 1.6e-75 253.8 0.0 2.1e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF812 PF05667.9 148675.1_53721120_3 - 0.001 17.9 0.1 0.0012 17.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) HAUS5 PF14817.4 148675.1_53721120_3 - 0.0082 14.7 0.4 0.0087 14.6 0.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF4200 PF13863.4 148675.1_53721120_3 - 0.012 15.8 4.4 0.019 15.2 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DivIC PF04977.13 148675.1_53721120_3 - 0.034 13.8 4.1 0.055 13.1 4.1 1.3 1 0 0 1 1 1 0 Septum formation initiator ADIP PF11559.6 148675.1_53721120_3 - 0.034 14.1 1.4 0.059 13.3 1.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.19 148675.1_53721120_3 - 0.043 13.8 1.9 0.043 13.8 1.9 1.6 1 1 0 1 1 1 0 bZIP transcription factor TPD52 PF04201.13 148675.1_53721120_3 - 0.044 13.2 1.6 0.077 12.5 1.6 1.3 1 0 0 1 1 1 0 Tumour protein D52 family DUF1192 PF06698.9 148675.1_53721120_3 - 0.05 13.5 7.5 0.05 13.5 7.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.13 148675.1_53721120_3 - 0.07 13.1 3.9 0.17 11.9 3.9 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Pkip-1 PF06878.9 148675.1_53721120_3 - 0.089 12.8 0.3 0.12 12.4 0.3 1.1 1 0 0 1 1 1 0 Pkip-1 protein DUF4140 PF13600.4 148675.1_53721120_3 - 0.099 13.0 3.5 0.16 12.3 3.5 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) LPP PF04728.11 148675.1_53721120_3 - 0.26 11.5 2.0 0.31 11.3 0.5 1.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper GrpE PF01025.17 148675.1_53721120_3 - 0.57 9.7 3.7 0.78 9.3 3.7 1.1 1 0 0 1 1 1 0 GrpE Casc1_N PF15927.3 148675.1_53721120_3 - 2.7 7.5 11.8 3.8 7.0 11.8 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Methyltransf_16 PF10294.7 001151296.2_53723001_2 - 4.1e-26 91.6 0.0 5.5e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.4 001151296.2_53723001_2 - 0.001 18.8 0.0 0.0031 17.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001151296.2_53723001_2 - 0.028 15.0 0.1 0.071 13.7 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain NodS PF05401.9 001151296.2_53723001_2 - 0.11 11.9 0.1 1.1 8.7 0.1 2.1 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_23 PF13489.4 001151296.2_53723001_2 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cmc1 PF08583.8 001151360.3_53722001_1 - 0.022 14.7 5.1 0.032 14.1 0.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.7 001151360.3_53722001_1 - 0.087 13.0 8.7 15 5.8 6.9 2.8 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Arch_flagellin PF01917.14 001151473.2_53722001_2 - 0.11 12.5 6.2 0.16 12.0 6.2 1.1 1 0 0 1 1 1 0 Archaebacterial flagellin DUF716 PF04819.10 148719.1_53722120_1 - 0.0097 15.5 0.5 0.017 14.8 0.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF716) DUF3774 PF12609.6 148720.1_53724120_1 - 1e-08 36.0 0.4 1e-08 36.0 0.4 1.8 2 0 0 2 2 2 1 Wound-induced protein ABC2_membrane PF01061.22 001152509.2_53725001_2 - 3e-44 150.8 21.8 3e-44 150.8 21.8 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.25 001152509.2_53725001_2 - 1.7e-22 80.3 0.0 2.5e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.4 001152509.2_53725001_2 - 6.2e-06 26.1 1.1 0.066 12.9 0.2 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.4 001152509.2_53725001_2 - 2.4e-05 24.7 0.2 5e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.4 001152509.2_53725001_2 - 2.6e-05 23.7 0.2 6e-05 22.5 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.4 001152509.2_53725001_2 - 0.00018 21.0 0.6 0.001 18.6 0.3 2.1 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.5 001152509.2_53725001_2 - 0.00084 18.4 13.6 0.0017 17.4 13.6 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF258 PF03193.14 001152509.2_53725001_2 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.4 001152509.2_53725001_2 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.17 001152509.2_53725001_2 - 0.016 14.5 0.0 0.23 10.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.18 001152509.2_53725001_2 - 0.03 13.2 0.0 0.061 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.4 001152509.2_53725001_2 - 0.037 14.4 0.0 0.06 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.10 001152509.2_53725001_2 - 0.063 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.21 001152509.2_53725001_2 - 0.073 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.4 001152509.2_53725001_2 - 0.075 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.7 001152509.2_53725001_2 - 0.098 11.7 0.0 0.18 10.9 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.14 001152509.2_53725001_2 - 0.13 11.1 0.4 0.21 10.4 0.4 1.2 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.4 001152509.2_53725001_2 - 0.2 11.7 0.5 0.59 10.2 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.4 001152509.2_53725001_2 - 0.2 12.0 0.0 0.5 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.13 001152509.2_53725001_2 - 0.21 11.3 0.1 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 NTPase zf-HIT PF04438.14 148867.1_53725120_2 - 0.018 14.8 0.8 0.077 12.7 0.8 2.1 1 0 0 1 1 1 0 HIT zinc finger peroxidase PF00141.21 001152369.2_53723001_1 - 5.3e-59 199.5 0.0 6.5e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase UCR_Fe-S_N PF10399.7 001152369.2_53723001_3 - 0.047 12.9 2.1 0.24 10.7 2.1 2.3 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DDE_Tnp_4 PF13359.4 001152195.2_53723001_2 - 1.4e-11 44.2 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease bPH_6 PF10756.7 001152195.2_53723001_2 - 0.087 12.8 0.8 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial PH domain Trypan_PARP PF05887.9 001152195.2_53723001_2 - 0.81 9.6 8.8 0.36 10.7 6.2 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TPR_1 PF00515.26 148874.1_53726120_1 - 3.2e-17 61.4 1.0 0.00038 20.0 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.15 148874.1_53726120_1 - 1.6e-14 52.6 4.0 0.0062 16.4 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.4 148874.1_53726120_1 - 7.3e-13 47.5 0.2 0.047 13.8 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.4 148874.1_53726120_1 - 1.5e-12 46.8 0.1 0.019 15.2 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.4 148874.1_53726120_1 - 1.5e-12 46.8 0.4 7.1e-05 22.3 0.0 4.5 2 1 2 4 4 4 3 TPR repeat TPR_16 PF13432.4 148874.1_53726120_1 - 1.7e-12 47.7 6.1 1.5e-05 25.5 0.1 3.3 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.4 148874.1_53726120_1 - 3.3e-10 40.2 2.6 4.3e-07 30.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.4 148874.1_53726120_1 - 4.6e-09 36.2 4.3 0.02 15.5 0.0 4.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.4 148874.1_53726120_1 - 2.2e-08 34.1 4.3 0.0026 17.9 0.1 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.4 148874.1_53726120_1 - 9e-08 31.5 0.2 0.27 11.2 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.4 148874.1_53726120_1 - 3.2e-07 30.3 2.4 0.0085 16.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.4 148874.1_53726120_1 - 3.1e-06 26.7 6.7 0.67 9.8 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.4 148874.1_53726120_1 - 0.0012 19.2 1.8 2.9 8.6 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat YfdX PF10938.6 148874.1_53726120_1 - 0.013 15.3 1.1 0.026 14.3 0.3 1.8 1 1 1 2 2 2 0 YfdX protein TPR_20 PF14561.4 148874.1_53726120_1 - 0.024 14.8 0.4 0.85 9.9 0.1 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.5 148874.1_53726120_1 - 0.077 12.9 0.1 7.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) 4HB_MCP_1 PF12729.5 148874.1_53726120_1 - 0.19 11.1 0.1 0.33 10.4 0.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TPR_4 PF07721.12 148874.1_53726120_1 - 0.41 11.3 0.1 0.41 11.3 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat OapA_N PF08525.9 148874.1_53726120_1 - 1.6 8.6 4.7 3.3 7.6 4.7 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif cwf21 PF08312.10 001152014.2_53722001_2 - 3.3e-13 49.4 8.2 4.5e-13 49.0 8.2 1.2 1 0 0 1 1 1 1 cwf21 domain Histone_HNS PF00816.19 001152014.2_53722001_2 - 0.05 14.3 1.4 0.082 13.6 1.4 1.3 1 0 0 1 1 1 0 H-NS histone family DUF3511 PF12023.6 001152039.2_53722001_3 - 3.5e-23 81.0 1.7 5.5e-23 80.4 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3511) DUF4043 PF13252.4 001152073.2_53722001_2 - 0.072 12.1 0.3 0.098 11.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) Herpes_UL49_2 PF04823.10 001152073.2_53722001_3 - 0.017 15.1 2.5 0.028 14.4 2.5 1.3 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein DUF247 PF03140.13 001152019.2_53724001_2 - 1.2e-90 304.2 0.0 1.4e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Plant protein of unknown function VPEP PF07589.9 001151768.2_53722001_3 - 0.054 13.4 1.9 0.12 12.4 1.9 1.6 1 0 0 1 1 1 0 PEP-CTERM motif p450 PF00067.20 001152595.1_53724001_2 - 1.3e-90 304.2 0.0 1.6e-90 303.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CAP PF00188.24 001153579.2_53722001_2 - 9.2e-21 74.8 0.5 9.2e-21 74.8 0.5 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family TetR_C_11 PF16859.3 001153579.2_53722001_3 - 0.51 10.5 6.3 0.084 13.1 1.6 1.9 2 0 0 2 2 2 0 Bacterial transcriptional repressor C-terminal ANTH PF07651.14 001153610.2_53724001_2 - 2.2e-33 115.3 0.0 3.3e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 ANTH domain TAXi_C PF14541.4 001153550.2_53724001_1 - 2.9e-39 134.3 0.0 5e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.4 001153550.2_53724001_1 - 2.4e-31 109.2 2.0 4.1e-31 108.5 2.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.21 001153550.2_53724001_1 - 1e-19 71.0 0.0 4.5e-09 36.0 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic aspartyl protease PRA1 PF03208.17 001153719.2_53723001_2 - 2.3e-37 127.7 1.1 3.3e-37 127.2 1.1 1.2 1 0 0 1 1 1 1 PRA1 family protein Glyco_transf_20 PF00982.19 001153719.2_53723001_2 - 0.28 9.7 0.0 0.39 9.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 DUF3040 PF11239.6 001153719.2_53723001_2 - 1.1 9.5 7.4 1.5 9.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Pkinase_Tyr PF07714.15 001153740.2_53724001_1 - 1.3e-13 50.7 0.0 1.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001153740.2_53724001_1 - 1.2e-09 37.8 0.0 1.6e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Hamartin PF04388.10 001153740.2_53724001_1 - 5.9 5.3 7.8 7.8 4.9 7.8 1.1 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.7 001153740.2_53724001_1 - 6 5.9 13.5 8.4 5.4 13.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ank PF00023.28 001153576.2_53725001_3 - 4.5e-07 29.9 1.7 0.013 15.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.5 001153576.2_53725001_3 - 9.8e-06 25.9 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.4 001153576.2_53725001_3 - 4.1e-05 23.5 0.0 0.039 14.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.4 001153576.2_53725001_3 - 0.00036 20.9 0.0 0.001 19.4 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.4 001153576.2_53725001_3 - 0.0004 20.5 0.7 0.032 14.5 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-CCCH PF00642.22 001153576.2_53725001_3 - 0.00088 19.0 3.3 0.00088 19.0 3.3 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.4 001153576.2_53725001_3 - 0.1 12.9 10.2 0.81 10.1 0.4 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Oleosin PF01277.15 001349993.1_53722001_2 - 1.3e-30 105.3 9.2 1.8e-30 104.8 9.2 1.2 1 0 0 1 1 1 1 Oleosin MMR_HSR1 PF01926.21 001327826.1_53725001_3 - 8.4e-20 70.8 0.0 1.9e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001327826.1_53725001_3 - 4.9e-08 32.9 0.0 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FeoB_N PF02421.16 001327826.1_53725001_3 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.25 001327826.1_53725001_3 - 0.0008 18.9 0.0 0.027 13.9 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.21 001327826.1_53725001_3 - 0.0049 16.8 0.0 2.1 8.2 0.5 2.6 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.8 001327826.1_53725001_3 - 0.027 13.8 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AMP-binding PF00501.26 001154315.2_53724001_2 - 3.7e-96 322.2 0.0 4.7e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001154315.2_53724001_2 - 2.8e-21 76.2 0.5 6.9e-21 74.9 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Transferase PF02458.13 001154098.2_53724001_3 - 5.1e-41 140.6 0.0 7.1e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Transferase family Polysacc_synt_4 PF04669.11 001154937.2_53723001_2 - 1.8e-40 138.4 0.0 4.4e-40 137.1 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis AAA_assoc PF14363.4 001154596.3_53724001_1 - 1e-19 70.5 0.0 2.5e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Domain associated at C-terminal with AAA AAA PF00004.27 001154596.3_53724001_1 - 4.9e-16 59.2 0.0 1.4e-08 35.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 001154596.3_53724001_1 - 3.6e-05 24.1 0.3 0.0013 19.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.11 001154596.3_53724001_1 - 7.3e-05 21.9 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.12 001154596.3_53724001_1 - 0.0018 18.2 0.0 0.016 15.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.10 001154596.3_53724001_1 - 0.0018 17.4 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.4 001154596.3_53724001_1 - 0.0024 17.4 0.1 0.013 15.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.20 001154596.3_53724001_1 - 0.0092 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.4 001154596.3_53724001_1 - 0.016 14.8 0.0 0.044 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.4 001154596.3_53724001_1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.4 001154596.3_53724001_1 - 0.068 13.3 0.2 0.9 9.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Acid_PPase PF12689.5 001154596.3_53724001_1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase AAA_22 PF13401.4 001154596.3_53724001_1 - 0.16 12.1 0.1 0.76 9.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain Pkinase PF00069.23 001354805.1_53725001_3 - 4.8e-74 248.9 0.1 6e-74 248.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001354805.1_53725001_3 - 1.1e-35 123.0 0.0 1.5e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001354805.1_53725001_3 - 2.1e-10 40.3 0.1 2.1e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.22 001354805.1_53725001_3 - 1.2e-05 25.7 0.0 3.2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.12 001354805.1_53725001_3 - 1.6e-05 24.2 0.1 2.6e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.4 001354805.1_53725001_3 - 0.00095 18.7 0.2 0.84 9.1 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.21 001354805.1_53725001_3 - 0.0012 18.7 0.2 0.0031 17.3 0.2 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.20 001354805.1_53725001_3 - 0.018 14.5 1.9 0.04 13.4 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Ovate PF04844.11 001154805.3_53723001_2 - 1.5e-21 76.0 0.1 2.2e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor, ovate FAE1_CUT1_RppA PF08392.10 001154798.3_53724001_1 - 1.8e-100 335.8 0.0 2.5e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.8 001154798.3_53724001_1 - 4.9e-10 39.3 0.0 9.4e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_N PF00195.17 001154798.3_53724001_1 - 0.047 13.0 0.4 0.08 12.2 0.4 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.8 001154798.3_53724001_1 - 0.23 11.2 2.3 0.16 11.7 0.2 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ABC2_membrane PF01061.22 001154627.2_53725001_1 - 6.8e-43 146.4 17.3 9.5e-43 145.9 17.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.25 001154627.2_53725001_1 - 4.3e-28 98.4 0.0 6.6e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.4 001154627.2_53725001_1 - 4.7e-07 29.8 0.9 0.026 14.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.4 001154627.2_53725001_1 - 0.00013 22.3 0.2 0.00034 20.9 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.17 001154627.2_53725001_1 - 0.00017 21.0 0.1 0.037 13.3 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.5 001154627.2_53725001_1 - 0.00036 19.6 13.0 0.00053 19.1 13.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_22 PF13401.4 001154627.2_53725001_1 - 0.00087 19.4 0.1 0.0039 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.14 001154627.2_53725001_1 - 0.004 16.9 0.3 0.0087 15.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.4 001154627.2_53725001_1 - 0.0087 15.6 0.3 0.018 14.6 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PDR_assoc PF08370.9 001154627.2_53725001_1 - 0.0089 15.6 0.2 0.029 13.9 0.2 1.8 1 0 0 1 1 1 1 Plant PDR ABC transporter associated MMR_HSR1 PF01926.21 001154627.2_53725001_1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.4 001154627.2_53725001_1 - 0.032 14.6 0.0 0.087 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.13 001154627.2_53725001_1 - 0.034 12.9 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.4 001154627.2_53725001_1 - 0.046 13.3 0.1 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.4 001154627.2_53725001_1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.4 001154627.2_53725001_1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain DuoxA PF10204.7 001154627.2_53725001_1 - 0.91 8.3 5.9 1.5 7.6 5.9 1.2 1 0 0 1 1 1 0 Dual oxidase maturation factor PPR PF01535.18 001154575.3_53724001_1 - 4.6e-42 139.2 7.2 4.6e-08 32.7 0.0 9.3 9 0 0 9 9 9 7 PPR repeat PPR_2 PF13041.4 001154575.3_53724001_1 - 1.9e-39 133.5 0.0 3.2e-12 46.3 0.0 8.1 5 2 3 8 8 8 6 PPR repeat family DYW_deaminase PF14432.4 001154575.3_53724001_1 - 1.1e-36 125.3 0.1 1.7e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases PPR_1 PF12854.5 001154575.3_53724001_1 - 6.7e-31 105.6 3.4 3.3e-06 26.6 0.0 6.9 6 0 0 6 6 6 6 PPR repeat PPR_3 PF13812.4 001154575.3_53724001_1 - 5.1e-16 58.4 0.0 0.0014 18.5 0.0 6.8 5 2 2 7 7 7 4 Pentatricopeptide repeat domain PPR_long PF17177.2 001154575.3_53724001_1 - 3.5e-11 42.7 0.0 7.8e-06 25.3 0.0 3.2 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001154575.3_53724001_1 - 0.00018 21.9 0.1 22 6.1 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.4 001154575.3_53724001_1 - 0.018 15.6 0.0 7.8 7.2 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.15 001154575.3_53724001_1 - 0.065 13.5 0.1 1.3 9.3 0.0 2.8 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_19 PF14559.4 001154575.3_53724001_1 - 0.08 13.3 0.0 16 6.0 0.0 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat PH PF00169.27 001155157.2_53722001_2 - 2.4e-19 69.7 0.0 3.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 001155157.2_53722001_2 - 2.5e-08 34.2 0.5 6.2e-08 32.9 0.5 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.4 001155157.2_53722001_2 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.4 001155157.2_53722001_2 - 0.00056 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.4 001155157.2_53722001_2 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.8 001155157.2_53722001_2 - 0.02 15.1 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Presenilin PF01080.15 001155799.2_53724001_2 - 1.5e-127 425.6 0.4 1.8e-127 425.3 0.4 1.0 1 0 0 1 1 1 1 Presenilin Myb_DNA-bind_4 PF13837.4 001155558.2_53723001_2 - 6.3e-24 84.1 0.0 1.5e-23 82.9 0.0 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.5 001155558.2_53723001_2 - 0.0077 16.9 0.0 0.018 15.7 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.7 001155558.2_53723001_2 - 0.031 14.5 0.4 0.09 13.0 0.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PMEI PF04043.13 001155260.3_53722001_2 - 5.3e-15 55.9 1.7 8.3e-15 55.3 1.7 1.3 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor ATP-synt_B PF00430.16 001155474.2_53722001_2 - 2.5e-12 46.9 10.7 4.1e-12 46.2 10.7 1.3 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Apolipoprotein PF01442.16 001155474.2_53722001_2 - 0.023 14.5 12.5 0.061 13.1 12.4 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phasin PF05597.9 001155474.2_53722001_2 - 0.032 14.1 8.2 0.048 13.6 8.2 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.8 001155474.2_53722001_2 - 0.08 13.0 0.6 0.11 12.5 0.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.10 001155474.2_53722001_2 - 0.16 11.9 2.6 0.47 10.4 2.7 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.9 001155474.2_53722001_2 - 0.35 10.5 11.4 0.53 10.0 11.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3584 PF12128.6 001155474.2_53722001_2 - 0.77 7.1 7.9 1 6.7 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.4 001155474.2_53722001_2 - 4.3 6.5 14.9 0.09 12.0 5.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) zf-RING_2 PF13639.4 001155202.2_53722001_3 - 3.6e-10 39.8 5.4 6.9e-10 38.9 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 001155202.2_53722001_3 - 7.7e-10 38.8 2.2 1.4e-09 38.0 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001155202.2_53722001_3 - 1.1e-08 34.7 1.9 2e-08 33.8 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001155202.2_53722001_3 - 4.7e-08 32.6 3.0 7.8e-08 31.9 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.3 001155202.2_53722001_3 - 9.1e-07 28.4 0.6 1.7e-06 27.5 0.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.5 001155202.2_53722001_3 - 6.8e-06 25.9 0.9 1.2e-05 25.1 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.4 001155202.2_53722001_3 - 1.7e-05 24.6 1.9 2.9e-05 23.8 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.4 001155202.2_53722001_3 - 0.0014 18.3 3.0 0.0026 17.4 3.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.4 001155202.2_53722001_3 - 0.0017 18.3 0.5 0.0054 16.7 0.5 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.4 001155202.2_53722001_3 - 0.0031 17.4 3.1 0.0073 16.2 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.3 001155202.2_53722001_3 - 0.0037 16.7 3.6 0.0075 15.7 3.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.4 001155202.2_53722001_3 - 0.0072 16.0 2.7 0.016 14.9 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.5 001155202.2_53722001_3 - 0.01 15.8 6.5 0.024 14.6 6.5 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.4 001155202.2_53722001_3 - 0.012 15.2 2.5 0.023 14.3 2.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glutaredoxin PF00462.22 001154543.2_53722001_1 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin F-box PF00646.31 001155692.2_53723001_3 - 0.0011 18.7 2.4 0.0051 16.5 2.6 2.1 2 0 0 2 2 2 1 F-box domain PUNUT PF16913.3 001156026.2_53724001_2 - 1.5e-77 260.8 16.8 1.9e-77 260.5 16.8 1.1 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.18 001156026.2_53724001_2 - 0.0011 19.0 14.7 0.0011 19.0 14.7 2.3 2 0 0 2 2 2 1 EamA-like transporter family RALF PF05498.9 001156170.2_53722001_1 - 2e-22 79.6 2.0 4.5e-22 78.5 2.0 1.5 1 0 0 1 1 1 1 Rapid ALkalinization Factor (RALF) SPX PF03105.17 001155769.2_53723001_1 - 3.4e-24 86.4 8.8 2.7e-09 37.4 0.1 3.1 1 1 2 3 3 3 3 SPX domain AgrB PF04647.13 001156160.2_53722001_1 - 0.14 11.3 2.8 0.18 11.0 2.8 1.1 1 0 0 1 1 1 0 Accessory gene regulator B OAD_gamma PF04277.11 001156160.2_53722001_1 - 0.53 10.8 3.0 1 9.8 3.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AgrB PF04647.13 001156160.2_53722001_2 - 0.037 13.2 2.2 0.048 12.8 2.2 1.1 1 0 0 1 1 1 0 Accessory gene regulator B OAD_gamma PF04277.11 001156160.2_53722001_2 - 0.68 10.4 3.5 1 9.8 3.5 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PMEI PF04043.13 001156160.2_53722001_3 - 3.8e-15 56.4 1.9 8e-15 55.4 1.9 1.6 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor DNA_pol_A_exo1 PF01612.18 001156614.3_53722001_1 - 1.5e-13 50.7 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Glyoxal_oxid_N PF07250.9 001156469.2_53725001_3 - 2.2e-110 367.4 0.0 1.1e-107 358.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.9 001156469.2_53725001_3 - 2e-26 91.9 0.1 4.1e-26 91.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.4 001156469.2_53725001_3 - 0.00098 18.9 2.1 0.69 9.8 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain LEA_2 PF03168.11 149077.1_53723120_3 - 9.2e-15 54.9 0.1 1.4e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein zf-Dof PF02701.13 001156857.2_53723001_1 - 8.2e-32 109.0 11.1 1.3e-31 108.4 11.1 1.3 1 0 0 1 1 1 1 Dof domain, zinc finger DUF4083 PF13314.4 001156857.2_53723001_1 - 3.9 7.4 5.6 7.1 6.5 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Kin17_mid PF10357.7 001156670.2_53724001_2 - 2.8e-45 153.1 0.3 2.8e-45 153.1 0.3 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KOW PF00467.27 001156670.2_53724001_2 - 0.008 16.0 0.0 0.008 16.0 0.0 2.9 4 0 0 4 4 4 1 KOW motif DUF3252 PF11623.6 001156670.2_53724001_2 - 0.057 12.9 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3252) DNA_ligase_A_C PF04679.13 001156670.2_53724001_2 - 0.087 13.3 0.2 0.43 11.1 0.2 2.2 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region zf-met PF12874.5 001156670.2_53724001_2 - 0.14 12.4 8.5 0.34 11.2 8.5 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001156670.2_53724001_2 - 0.61 10.3 8.8 1.4 9.2 8.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding MAJIN PF15077.4 001156670.2_53724001_2 - 0.65 9.7 4.5 0.077 12.8 0.5 1.5 2 0 0 2 2 2 0 Membrane-anchored junction protein DUF4407 PF14362.4 001156670.2_53724001_2 - 1.5 7.9 4.4 2.3 7.4 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RALF PF05498.9 001157205.2_53722001_1 - 4e-27 94.7 1.8 4e-27 94.7 1.8 1.7 2 0 0 2 2 2 1 Rapid ALkalinization Factor (RALF) Ribosomal_S9 PF00380.17 001157508.2_53722001_2 - 2.4e-31 108.7 0.8 3e-31 108.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2102 PF09875.7 001157508.2_53722001_2 - 0.11 12.1 0.2 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) zf-RING_2 PF13639.4 001157317.2_53723001_2 - 1.3e-12 47.6 4.5 1.3e-12 47.6 4.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.3 001157317.2_53723001_2 - 2.9e-08 33.2 0.3 5.1e-08 32.4 0.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.5 001157317.2_53723001_2 - 3.2e-08 33.6 3.6 3.2e-08 33.6 3.6 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.4 001157317.2_53723001_2 - 4.7e-08 32.6 3.2 8.8e-08 31.7 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001157317.2_53723001_2 - 9.3e-08 31.7 2.0 1.7e-07 30.9 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001157317.2_53723001_2 - 1.3e-05 24.9 2.6 2.2e-05 24.2 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.4 001157317.2_53723001_2 - 1.7e-05 24.5 3.2 2.9e-05 23.7 3.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.4 001157317.2_53723001_2 - 6e-05 22.7 2.7 0.0001 22.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001157317.2_53723001_2 - 6.9e-05 22.7 1.1 0.00013 21.8 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.4 001157317.2_53723001_2 - 0.00011 22.1 1.1 0.0002 21.2 1.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.3 001157317.2_53723001_2 - 0.00014 21.3 3.2 0.00014 21.3 3.2 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.4 001157317.2_53723001_2 - 0.0037 16.8 2.5 0.0059 16.2 2.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.5 001157317.2_53723001_2 - 0.025 14.6 5.5 0.025 14.6 5.5 1.9 2 0 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.9 001157317.2_53723001_2 - 0.037 14.2 4.3 0.083 13.1 4.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.3 001157317.2_53723001_2 - 0.9 9.5 3.6 2.4 8.1 3.6 1.7 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.6 001157317.2_53723001_2 - 1.1 9.4 5.9 5.2 7.2 5.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.4 001157317.2_53723001_2 - 2.5 8.2 5.2 0.33 11.0 1.0 1.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING ubiquitin PF00240.21 001354987.1_53722001_2 - 2.7e-06 26.9 0.2 5.1e-06 26.0 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.4 001354987.1_53722001_2 - 0.00015 22.0 0.1 0.00045 20.5 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain PAP1 PF08601.8 001354987.1_53722001_3 - 4.7 6.7 6.0 6.2 6.3 6.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF761 PF05553.9 001157748.2_53724001_1 - 1.9e-12 46.3 3.5 4.1e-12 45.3 3.5 1.5 1 0 0 1 1 1 1 Cotton fibre expressed protein CAP_N PF01213.17 001157748.2_53724001_1 - 3.5 6.9 12.8 0.65 9.3 9.0 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.23 001346906.1_53727001_2 - 2.1e-71 240.2 0.0 3.5e-71 239.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001346906.1_53727001_2 - 1.8e-32 112.5 0.0 2.8e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001346906.1_53727001_2 - 2e-06 27.2 0.4 0.00042 19.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.20 001346906.1_53727001_2 - 0.057 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.12 001346906.1_53727001_2 - 0.15 11.3 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.5 001318232.1_53726001_2 - 0.0016 18.7 2.0 1.5 9.2 0.0 5.5 5 3 3 8 8 8 1 Leucine Rich repeats (2 copies) F-box-like PF12937.5 001318232.1_53726001_2 - 0.0024 17.6 0.1 0.01 15.6 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001318232.1_53726001_2 - 0.044 13.6 0.0 0.18 11.6 0.0 2.1 1 0 0 1 1 1 0 F-box domain DUF1409 PF07197.10 001318232.1_53726001_2 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) LRR_6 PF13516.4 001318232.1_53726001_2 - 1.1 9.3 11.8 25 5.1 0.0 6.7 8 0 0 8 8 8 0 Leucine Rich repeat PP2C PF00481.19 001347910.1_53725001_2 - 7.1e-31 107.6 0.0 4.1e-30 105.1 0.0 1.9 1 1 1 2 2 2 1 Protein phosphatase 2C HSP90 PF00183.16 001310034.1_53725001_2 - 6e-241 800.6 30.0 7.6e-241 800.3 30.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.24 001310034.1_53725001_2 - 1.4e-14 54.5 0.1 2.8e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001310034.1_53725001_2 - 3.7e-10 39.6 0.1 9.1e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.7 001310034.1_53725001_2 - 0.11 12.4 0.7 0.25 11.2 0.1 1.9 2 0 0 2 2 2 0 Tumour suppressor protein PTPRCAP PF15713.3 001310034.1_53725001_2 - 6.2 7.0 13.0 0.28 11.3 6.8 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Pollen_allerg_1 PF01357.19 001322359.1_53723001_2 - 1.7e-16 59.9 0.0 2.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001322359.1_53723001_2 - 0.032 14.4 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Lytic transglycolase DPBB_1 PF03330.16 001322359.1_53723001_3 - 0.022 14.9 0.1 0.049 13.8 0.1 1.6 1 0 0 1 1 1 0 Lytic transglycolase WRKY PF03106.13 001321638.1_53723001_3 - 4.5e-24 84.4 1.1 8.9e-24 83.5 1.1 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain zf-RING_2 PF13639.4 001321418.1_53723001_1 - 1.2e-13 50.9 4.3 2.7e-13 49.8 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001321418.1_53723001_1 - 9.3e-10 37.9 1.5 2.2e-09 36.7 1.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001321418.1_53723001_1 - 3.5e-09 36.2 4.0 6.6e-09 35.3 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001321418.1_53723001_1 - 3.3e-08 33.6 6.3 8.9e-08 32.2 6.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001321418.1_53723001_1 - 9.8e-06 25.2 2.4 1.9e-05 24.3 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001321418.1_53723001_1 - 3.2e-05 23.7 0.1 8.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.5 001321418.1_53723001_1 - 5.3e-05 23.1 0.8 0.00012 22.0 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.4 001321418.1_53723001_1 - 0.00024 20.8 3.2 0.00024 20.8 3.2 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.4 001321418.1_53723001_1 - 0.00024 20.7 2.2 0.00024 20.7 2.2 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001321418.1_53723001_1 - 0.00028 20.7 3.2 0.00053 19.8 1.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.3 001321418.1_53723001_1 - 0.0035 16.8 3.6 0.0076 15.7 3.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.4 001321418.1_53723001_1 - 0.038 13.8 0.9 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.5 001321418.1_53723001_1 - 0.19 11.8 4.4 0.57 10.2 3.5 2.2 2 0 0 2 2 2 0 RING-variant domain Syndecan PF01034.18 001321418.1_53723001_1 - 0.3 10.9 0.5 0.62 9.9 0.5 1.4 1 0 0 1 1 1 0 Syndecan domain FANCL_C PF11793.6 001321418.1_53723001_1 - 1 9.5 4.1 5.4 7.1 4.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.3 001321418.1_53723001_1 - 1.5 9.0 4.5 3.4 7.8 4.5 1.6 1 1 0 1 1 1 0 Zinc-ribbon like family Smg4_UPF3 PF03467.13 001346661.1_53726001_2 - 2e-48 164.6 0.3 3.3e-48 163.9 0.3 1.4 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_2 PF04059.10 001346661.1_53726001_2 - 0.00018 21.6 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 SNF2_N PF00176.21 001347190.1_53728001_3 - 1.7e-47 161.8 0.0 3.3e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.29 001347190.1_53728001_3 - 2.4e-18 66.4 0.2 8e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001347190.1_53728001_3 - 1.9e-07 31.1 0.0 5.4e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.4 001347190.1_53728001_3 - 1.2e-05 24.3 0.0 3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 GCOM2 PF15328.4 001347190.1_53728001_3 - 0.044 14.0 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Mito_fiss_reg PF05308.9 001347190.1_53728001_3 - 0.053 13.5 1.2 0.14 12.1 1.2 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator TT_ORF2 PF02957.13 001347190.1_53728001_3 - 0.28 12.0 1.6 0.53 11.1 0.7 1.9 1 1 1 2 2 2 0 TT viral ORF2 Rhomboid PF01694.20 001348921.1_53725001_3 - 5.1e-30 104.3 7.5 5.1e-30 104.3 7.5 1.7 2 0 0 2 2 2 1 Rhomboid family YjeF_N PF03853.13 001327881.1_53725001_2 - 9.3e-35 119.9 0.0 1.6e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pyridox_oxidase PF01243.18 001327881.1_53725001_2 - 3.5e-26 91.1 0.0 6e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.7 001327881.1_53725001_2 - 4.9e-18 64.8 1.4 8.6e-18 64.0 1.4 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.5 001327881.1_53725001_2 - 0.00018 21.9 0.0 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.3 001327881.1_53725001_2 - 0.0023 17.4 0.0 0.013 14.9 0.0 2.1 3 0 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase like DUF936 PF06075.10 001323345.1_53726001_3 - 6.8e-231 768.8 16.8 7.7e-231 768.7 16.8 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) DALR_1 PF05746.13 001323345.1_53726001_3 - 0.025 14.6 0.7 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 DALR anticodon binding domain Branch PF02485.19 001324163.1_53725001_2 - 4.8e-60 203.0 0.0 6.5e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF2985 PF11204.6 001322496.1_53726001_3 - 1.9e-27 95.1 1.6 1.9e-27 95.1 1.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) PLAC8 PF04749.15 001322496.1_53726001_3 - 6.6e-19 68.6 6.9 6.6e-19 68.6 6.9 2.2 3 0 0 3 3 3 1 PLAC8 family SMK-1 PF04802.13 001349054.1_53727001_3 - 1.2e-66 224.1 3.7 1.2e-66 224.1 3.7 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 DUF566 PF04484.10 001347046.1_53725001_1 - 1.7e-98 330.0 0.6 1.7e-98 330.0 0.6 3.1 2 1 0 2 2 2 1 Family of unknown function (DUF566) Endosulfine PF04667.15 001347046.1_53725001_1 - 0.11 12.5 0.6 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region Glyco_tranf_2_3 PF13641.4 001196584.2_53725001_3 - 5.1e-23 82.1 0.0 7.4e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.4 001196584.2_53725001_3 - 1.4e-20 73.9 1.7 1.4e-20 73.9 1.7 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.24 001196584.2_53725001_3 - 1.9e-15 57.0 0.0 2.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.13 001196584.2_53725001_3 - 0.03 12.8 1.1 0.89 8.0 0.0 2.4 1 1 1 2 2 2 0 Chitin synthase KH_1 PF00013.27 001308612.1_53724001_3 - 1.1e-47 159.6 7.4 9.5e-16 57.3 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.15 001308612.1_53724001_3 - 2e-12 46.6 2.9 0.0079 15.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.4 001308612.1_53724001_3 - 5.9e-09 35.5 0.4 0.31 10.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.4 001308612.1_53724001_3 - 0.011 15.7 4.9 0.95 9.5 0.4 3.2 3 0 0 3 3 3 0 NusA-like KH domain zf-RING_2 PF13639.4 001324269.1_53724001_3 - 1.5e-13 50.6 3.7 3.3e-13 49.5 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.4 001324269.1_53724001_3 - 4e-10 39.2 4.3 7.6e-10 38.3 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001324269.1_53724001_3 - 3.4e-09 36.7 6.7 9.2e-09 35.3 6.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001324269.1_53724001_3 - 7.2e-09 35.2 4.3 1.3e-08 34.4 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.3 001324269.1_53724001_3 - 2.1e-08 33.6 1.3 4.4e-08 32.6 1.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.4 001324269.1_53724001_3 - 3.3e-06 26.8 3.8 6.4e-06 25.9 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001324269.1_53724001_3 - 5.5e-06 26.2 1.4 1.1e-05 25.2 1.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 001324269.1_53724001_3 - 1e-05 25.2 2.2 2.3e-05 24.0 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001324269.1_53724001_3 - 0.00011 22.0 6.1 0.00023 21.0 6.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.3 001324269.1_53724001_3 - 0.0051 16.3 3.0 0.01 15.3 3.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.5 001324269.1_53724001_3 - 0.1 12.6 5.8 0.22 11.6 5.8 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.6 001324269.1_53724001_3 - 0.11 12.6 4.3 0.28 11.3 4.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.4 001324269.1_53724001_3 - 4.1 7.2 7.5 9.8 6.0 7.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Autophagy_act_C PF03987.13 001306063.1_53723001_1 - 1.9e-18 66.7 0.9 6.7e-18 64.9 0.8 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain DUF632 PF04782.10 001348000.1_53729001_1 - 2.2e-105 352.3 1.0 3e-105 351.8 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF632) DUF630 PF04783.10 001348000.1_53729001_1 - 7.9e-22 77.1 2.7 7.9e-22 77.1 2.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF630) DUF295 PF03478.16 001150076.2_53724001_1 - 1.7e-08 34.0 0.1 4.3e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF295) Nrap PF03813.12 001348338.1_53728001_1 - 6.8e-248 825.0 0.0 7.9e-248 824.8 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Autophagy_act_C PF03987.13 001306062.1_53723001_1 - 1.8e-18 66.7 1.0 6.7e-18 64.9 0.8 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain SET PF00856.26 001329043.1_53729001_2 - 1.2e-18 68.0 0.1 1.2e-18 68.0 0.1 3.0 3 0 0 3 3 3 1 SET domain zf-HC5HC2H_2 PF13832.4 001329043.1_53729001_2 - 1.3e-15 57.4 1.3 1.3e-15 57.4 1.3 4.8 6 0 0 6 6 6 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.4 001329043.1_53729001_2 - 3.5e-15 55.9 2.3 3.5e-15 55.9 2.3 4.5 3 1 1 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.4 001329043.1_53729001_2 - 4.8e-09 35.5 7.9 4.8e-09 35.5 7.9 4.1 3 0 0 3 3 3 1 PHD-finger Jas PF16135.3 001329043.1_53729001_2 - 0.0001 22.3 0.6 0.0001 22.3 0.6 3.1 3 0 0 3 3 3 1 TPL-binding domain in jasmonate signalling PHD PF00628.27 001329043.1_53729001_2 - 0.00015 21.5 12.0 0.00015 21.5 12.0 4.7 4 0 0 4 4 4 2 PHD-finger START PF01852.17 001111657.2_53727001_2 - 2.9e-51 173.7 0.0 1.1e-50 171.9 0.0 1.9 2 1 0 2 2 2 1 START domain Homeobox PF00046.27 001111657.2_53727001_2 - 2.9e-18 65.3 3.4 5.9e-18 64.3 3.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001111657.2_53727001_2 - 0.0023 17.6 0.1 0.0047 16.7 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain MRP-L20 PF12824.5 001111657.2_53727001_2 - 0.01 15.9 3.3 0.017 15.2 3.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 HTH_Tnp_1 PF01527.18 001111657.2_53727001_2 - 0.1 12.8 0.5 0.22 11.7 0.5 1.6 1 0 0 1 1 1 0 Transposase DivIC PF04977.13 001111657.2_53727001_2 - 0.56 9.9 3.0 0.82 9.4 1.4 2.0 2 0 0 2 2 2 0 Septum formation initiator NRBF2 PF08961.8 001111657.2_53727001_2 - 1.2 8.6 4.4 1.7 8.0 2.4 2.0 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.10 001111657.2_53727001_2 - 3.8 7.9 6.2 1.7 9.0 3.3 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Oxidored_q6 PF01058.20 001309849.1_53723001_2 - 1.5e-21 76.4 0.1 2.1e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase_Tyr PF07714.15 001322345.1_53725001_2 - 6.8e-46 156.5 0.0 9.8e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001322345.1_53725001_2 - 1.3e-45 155.7 0.0 1.8e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain M_domain PF12938.5 001322345.1_53725001_3 - 0.38 10.4 4.1 0.59 9.7 4.1 1.2 1 0 0 1 1 1 0 M domain of GW182 DUF810 PF05664.9 001346073.1_53729001_3 - 7.5e-270 897.1 0.0 9e-270 896.8 0.0 1.1 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) Kelch_1 PF01344.23 001348980.1_53725001_3 - 6.2e-28 96.0 11.9 3.6e-15 55.1 0.0 6.7 8 0 0 8 8 8 3 Kelch motif Kelch_6 PF13964.4 001348980.1_53725001_3 - 7.9e-15 54.4 7.9 6.7e-06 26.1 0.0 5.7 4 1 2 6 6 6 4 Kelch motif Kelch_4 PF13418.4 001348980.1_53725001_3 - 7.2e-12 45.0 0.8 5.6e-06 26.1 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.13 001348980.1_53725001_3 - 1.3e-07 31.1 1.2 0.045 13.6 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.4 001348980.1_53725001_3 - 4.8e-05 23.4 8.2 0.014 15.5 0.0 5.2 6 1 0 6 6 6 2 Galactose oxidase, central domain F-box PF00646.31 001348980.1_53725001_3 - 0.055 13.2 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 F-box domain Ku_N PF03731.13 001320881.1_53725001_2 - 3.4e-55 187.1 0.1 4.8e-55 186.5 0.1 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.14 001320881.1_53725001_2 - 3.6e-41 141.0 0.0 1.9e-40 138.6 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.12 001320881.1_53725001_2 - 8.3e-20 71.1 1.3 2.2e-19 69.8 0.1 2.3 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm SAP PF02037.25 001320881.1_53725001_2 - 3.6e-09 36.0 0.0 1e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 SAP domain CHASE PF03924.11 001347120.1_53729001_2 - 3.3e-36 124.9 0.6 9.5e-36 123.4 0.4 1.9 2 0 0 2 2 2 1 CHASE domain HATPase_c PF02518.24 001347120.1_53729001_2 - 1.4e-28 99.5 0.0 4.3e-28 98.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.22 001347120.1_53729001_2 - 5.2e-21 74.8 0.1 8.3e-19 67.7 0.0 3.2 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.23 001347120.1_53729001_2 - 2e-18 66.1 0.0 5e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ELO PF01151.16 001347120.1_53729001_2 - 0.12 11.7 0.5 0.22 10.9 0.5 1.3 1 0 0 1 1 1 0 GNS1/SUR4 family Glyco_hydro_16 PF00722.19 001157631.2_53723001_2 - 6.4e-62 208.0 0.5 9.1e-62 207.5 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 XET_C PF06955.10 001157631.2_53723001_2 - 1.2e-20 73.0 1.2 2.2e-20 72.2 1.2 1.4 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus GRAS PF03514.12 001309851.1_53726001_3 - 4.2e-135 450.4 0.0 5.2e-135 450.1 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family DELLA PF12041.6 001309851.1_53726001_3 - 1.3e-35 121.0 0.1 2.4e-35 120.1 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator DELLA protein N terminal Motile_Sperm PF00635.24 001165715.2_53723001_3 - 5.4e-28 96.9 0.2 1e-27 96.0 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.3 001165715.2_53723001_3 - 0.0056 16.7 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF2721 PF11026.6 001165715.2_53723001_3 - 0.044 13.5 0.1 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF972 PF06156.11 001165715.2_53723001_3 - 2.9 8.4 5.5 7.3 7.1 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ALMT PF11744.6 001346994.1_53724001_3 - 1.9e-133 445.6 1.2 1.3e-128 429.7 0.1 2.1 1 1 1 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.4 001346994.1_53724001_3 - 1.2e-10 41.5 12.4 2.4e-10 40.5 12.4 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.10 001346994.1_53724001_3 - 2.9e-05 22.7 20.3 2.9e-05 22.7 20.3 1.8 2 1 0 2 2 2 1 Fusaric acid resistance protein family Herpes_UL73 PF03554.11 001346994.1_53724001_3 - 0.0044 16.9 0.4 0.015 15.2 0.4 1.9 1 0 0 1 1 1 1 UL73 viral envelope glycoprotein zf-C2H2_6 PF13912.4 001157837.2_53723001_3 - 2.8e-24 84.4 2.3 3.2e-12 46.0 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.4 001157837.2_53723001_3 - 8.4e-05 23.0 10.7 0.029 15.1 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.24 001157837.2_53723001_3 - 0.00053 20.2 1.5 0.82 10.1 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 001157837.2_53723001_3 - 0.0033 17.6 0.1 0.044 14.0 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.3 001157837.2_53723001_3 - 0.033 14.3 0.1 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.5 001157837.2_53723001_3 - 0.11 12.7 0.1 25 5.2 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_DME PF15628.4 001320528.1_53729001_3 - 4.8e-53 177.4 0.0 1.3e-52 176.0 0.0 1.8 1 0 0 1 1 1 1 RRM in Demeter Perm-CXXC PF15629.4 001320528.1_53729001_3 - 8.1e-14 51.5 4.4 8.1e-14 51.5 4.4 2.3 2 0 0 2 2 2 1 Permuted single zf-CXXC unit HhH-GPD PF00730.23 001320528.1_53729001_3 - 0.00092 19.5 0.0 0.0026 18.1 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.7 001320528.1_53729001_3 - 1.9 8.8 6.7 6.5 7.1 6.7 2.0 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DUF563 PF04577.12 001323014.1_53724001_2 - 3.6e-18 66.3 0.0 6.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Antimicrobial_5 PF08026.9 001112600.2_53723001_2 - 0.046 13.6 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Bee antimicrobial peptide Ribonuclease_T2 PF00445.16 001112600.2_53723001_3 - 9.3e-31 107.3 0.0 1.2e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family NDK PF00334.17 001310025.1_53722001_3 - 2.2e-54 183.0 0.0 2.9e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Autophagy_act_C PF03987.13 131257.1_53723120_1 - 0.0024 18.3 1.5 0.0062 17.0 1.5 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_act_C PF03987.13 131257.1_53723120_2 - 4.2e-08 33.5 0.1 9.7e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Metallothio_PEC PF02068.14 001112029.2_53722001_3 - 8.8e-23 80.3 47.8 8.8e-23 80.3 47.8 2.7 3 0 0 3 3 3 1 Plant PEC family metallothionein Ribosomal_S21e PF01249.16 001112007.3_53722001_1 - 1.4e-37 127.5 0.0 2.1e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e Profilin PF00235.17 001112152.2_53722001_2 - 1.1e-42 145.2 0.0 1.3e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Profilin MGC-24 PF05283.9 001112024.4_53722001_1 - 5.1 7.4 6.7 9 6.6 6.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ribosomal_S17 PF00366.18 001112024.4_53722001_3 - 3.4e-24 84.6 1.0 5e-24 84.1 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 UDPGT PF00201.16 001158074.2_53724001_3 - 2.2e-19 69.5 0.0 3.3e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase p450 PF00067.20 001157893.2_53724001_2 - 2e-110 369.6 0.0 2.3e-110 369.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL PF00657.20 001355217.1_53724001_2 - 1.5e-17 64.1 0.0 1.9e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.20 001158178.2_53724001_2 - 1.6e-73 247.9 0.0 1.9e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CiPC PF15800.3 001158224.2_53723001_1 - 0.1 12.2 1.8 0.13 11.8 1.8 1.2 1 0 0 1 1 1 0 Clock interacting protein circadian ZF-HD_dimer PF04770.10 001158224.2_53723001_3 - 1.9e-22 79.2 8.2 5.3e-22 77.8 8.2 1.6 1 0 0 1 1 1 1 ZF-HD protein dimerisation region HTH_Tnp_1 PF01527.18 001158224.2_53723001_3 - 0.00062 19.9 1.8 0.39 10.9 0.9 2.4 2 0 0 2 2 2 2 Transposase zf-RRN7 PF11781.6 001158224.2_53723001_3 - 0.13 11.8 3.3 4.4 7.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Homeobox PF00046.27 001158224.2_53723001_3 - 0.24 11.1 2.5 3 7.6 2.5 2.3 1 1 0 1 1 1 0 Homeobox domain EF-hand_1 PF00036.30 001158263.2_53722001_3 - 7.9e-33 109.4 5.0 3.2e-07 29.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001158263.2_53722001_3 - 1.2e-27 94.0 3.9 1.7e-06 27.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001158263.2_53722001_3 - 1.6e-24 83.5 1.3 1.2e-06 27.9 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001158263.2_53722001_3 - 8.3e-22 77.3 1.3 5.9e-11 42.5 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001158263.2_53722001_3 - 3.9e-21 74.4 8.5 3.2e-12 45.9 0.3 3.3 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001158263.2_53722001_3 - 0.01 16.0 0.0 3.7 7.8 0.0 2.4 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CCD48 PF15799.3 001158263.2_53722001_3 - 0.012 14.0 0.5 0.015 13.6 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF5132 PF17195.2 001158263.2_53722001_3 - 0.032 14.2 1.2 0.062 13.3 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) EF-hand_4 PF12763.5 001158263.2_53722001_3 - 0.079 12.8 0.4 0.75 9.6 0.0 2.4 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Excalibur PF05901.9 001158263.2_53722001_3 - 0.31 11.6 5.4 95 3.6 0.6 4.3 4 0 0 4 4 4 0 Excalibur calcium-binding domain VCBS PF13517.4 001158263.2_53722001_3 - 2.6 8.6 9.5 4.6 7.8 0.2 3.4 2 2 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Frataxin_Cyay PF01491.14 001157260.1_53722001_3 - 3e-38 130.1 0.0 5.4e-38 129.3 0.0 1.4 2 0 0 2 2 2 1 Frataxin-like domain PDT PF00800.16 001158712.2_53723001_1 - 1.2e-48 165.2 0.0 1.7e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase Pyridoxal_deC PF00282.17 001158825.2_53724001_3 - 1.8e-102 342.7 0.0 2.2e-102 342.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.19 001158825.2_53724001_3 - 8.9e-05 21.8 0.1 0.00015 21.1 0.1 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Skp1 PF01466.17 001158803.2_53722001_2 - 2.2e-28 98.0 1.4 4.8e-28 96.9 1.4 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.13 001158803.2_53722001_2 - 3.2e-24 84.7 0.6 6.8e-24 83.7 0.6 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain zf-RING_2 PF13639.4 001158859.2_53723001_1 - 2.8e-13 49.7 4.1 2.8e-13 49.7 4.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.5 001158859.2_53723001_1 - 2.8e-10 40.2 2.0 7.1e-10 38.9 2.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001158859.2_53723001_1 - 1.4e-09 37.3 0.7 1.4e-09 37.3 0.7 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001158859.2_53723001_1 - 5.5e-09 35.6 1.8 5.5e-09 35.6 1.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001158859.2_53723001_1 - 3e-06 26.9 0.9 6e-06 25.9 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001158859.2_53723001_1 - 2.4e-05 24.0 1.3 6.9e-05 22.6 1.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001158859.2_53723001_1 - 7.8e-05 22.3 3.0 7.8e-05 22.3 3.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001158859.2_53723001_1 - 0.00023 21.0 0.9 0.00044 20.1 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.4 001158859.2_53723001_1 - 0.00027 20.7 1.0 0.00061 19.6 1.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.3 001158859.2_53723001_1 - 0.00035 20.0 1.7 0.00095 18.6 1.7 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.4 001158859.2_53723001_1 - 0.0065 16.2 0.6 0.0065 16.2 0.6 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.6 001158859.2_53723001_1 - 0.0066 16.5 1.3 0.015 15.3 1.3 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.4 001158859.2_53723001_1 - 0.0073 16.0 2.5 0.015 15.0 2.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.9 001158859.2_53723001_1 - 0.11 12.7 1.6 0.31 11.2 1.6 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.3 001158859.2_53723001_1 - 0.12 12.3 0.8 0.33 10.9 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger peroxidase PF00141.21 001291638.1_53723001_1 - 1.5e-67 227.6 0.0 1.8e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Mito_carr PF00153.25 001139426.1_53724001_2 - 1.3e-68 226.8 0.5 5.2e-22 77.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CAF20 PF17052.3 001151121.1_53722001_1 - 0.73 9.8 2.9 0.95 9.5 0.2 2.0 1 1 1 2 2 2 0 Cap associated factor DnaJ_CXXCXGXG PF00684.17 001151121.1_53722001_3 - 6.1e-07 29.6 9.1 6.1e-07 29.6 9.1 2.6 1 1 2 3 3 3 2 DnaJ central domain Anti-TRAP PF15777.3 001151121.1_53722001_3 - 0.021 14.6 0.5 0.021 14.6 0.5 3.9 2 1 2 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein PHD_4 PF16866.3 001151121.1_53722001_3 - 0.51 10.3 9.3 0.37 10.8 0.4 3.3 3 1 0 3 3 3 0 PHD-finger DUF1356 PF07092.10 001151121.1_53722001_3 - 1.7 7.7 6.0 7.6 5.6 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Lar_restr_allev PF14354.4 001151121.1_53722001_3 - 2.8 8.2 11.9 0.33 11.2 2.1 3.4 2 1 2 4 4 4 0 Restriction alleviation protein Lar DUF573 PF04504.12 001318600.1_48624001_3 - 5.5e-26 90.9 0.2 5.5e-26 90.9 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF573 PRELI PF04707.12 001159219.2_53723001_1 - 8.5e-24 84.0 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family LEA_4 PF02987.14 001159215.2_53722001_3 - 4.5e-06 26.5 9.8 4.5e-06 26.5 9.8 2.2 2 0 0 2 2 2 1 Late embryogenesis abundant protein Dirigent PF03018.12 001165614.2_53722001_2 - 8.2e-49 165.2 0.1 1.2e-48 164.6 0.1 1.2 1 0 0 1 1 1 1 Dirigent-like protein Pollen_allerg_1 PF01357.19 001165517.3_53722001_1 - 1.1e-09 38.1 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Pollen allergen DUF588 PF04535.10 001157932.1_53722001_1 - 4.3e-42 143.3 13.8 6.3e-42 142.8 13.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) MIP PF00230.18 001111464.1_53723001_1 - 1.7e-83 279.7 11.9 2.1e-83 279.4 11.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Reticulon PF02453.15 001111464.1_53723001_1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.6 3 0 0 3 3 3 0 Reticulon Homoserine_dh PF00742.17 001112221.1_53727001_2 - 9.8e-54 181.7 0.1 4e-53 179.8 0.0 2.1 3 0 0 3 3 3 1 Homoserine dehydrogenase AA_kinase PF00696.26 001112221.1_53727001_2 - 6.2e-41 140.4 0.0 9.9e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family NAD_binding_3 PF03447.14 001112221.1_53727001_2 - 1.8e-28 99.4 0.0 4.4e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.23 001112221.1_53727001_2 - 1.7e-15 56.3 0.4 3.4e-08 33.0 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.4 001112221.1_53727001_2 - 6.1e-13 48.2 3.9 1.1e-05 25.0 0.1 3.2 3 0 0 3 3 3 2 ACT domain ACT_6 PF13740.4 001112221.1_53727001_2 - 0.03 14.2 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 ACT domain Iron_permease PF04120.10 001112221.1_53727001_2 - 0.046 13.4 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Low affinity iron permease Lon_C PF05362.11 001112425.2_53728001_2 - 5.1e-76 254.6 0.3 9.8e-76 253.7 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.14 001112425.2_53728001_2 - 3e-33 115.3 0.0 7.9e-33 114.0 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.27 001112425.2_53728001_2 - 8.2e-21 74.7 0.0 1.7e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.4 001112425.2_53728001_2 - 4.2e-06 26.5 0.1 8.3e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.10 001112425.2_53728001_2 - 1.1e-05 24.7 0.0 0.00011 21.4 0.0 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.4 001112425.2_53728001_2 - 1.2e-05 25.6 0.6 0.00035 20.8 0.0 3.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.12 001112425.2_53728001_2 - 5.5e-05 23.1 0.0 0.00017 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.12 001112425.2_53728001_2 - 0.00014 21.9 0.0 0.00037 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.4 001112425.2_53728001_2 - 0.00029 21.0 0.8 0.016 15.3 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.9 001112425.2_53728001_2 - 0.00034 19.5 0.0 0.00066 18.6 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.4 001112425.2_53728001_2 - 0.00074 19.9 0.1 0.0036 17.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.4 001112425.2_53728001_2 - 0.0085 15.7 0.5 0.021 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.4 001112425.2_53728001_2 - 0.012 16.0 5.8 1.7 8.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.9 001112425.2_53728001_2 - 0.013 15.2 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.15 001112425.2_53728001_2 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Cytidylate_kin PF02224.16 001112425.2_53728001_2 - 0.025 14.2 0.1 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase TIP49 PF06068.11 001112425.2_53728001_2 - 0.03 13.2 0.5 0.33 9.7 0.1 2.2 2 0 0 2 2 2 0 TIP49 C-terminus RNA_helicase PF00910.20 001112425.2_53728001_2 - 0.032 14.5 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.14 001112425.2_53728001_2 - 0.041 13.6 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SKI PF01202.20 001112425.2_53728001_2 - 0.049 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase AAA_14 PF13173.4 001112425.2_53728001_2 - 0.056 13.3 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.15 001112425.2_53728001_2 - 0.057 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.13 001112425.2_53728001_2 - 0.08 12.7 0.0 0.31 10.8 0.0 2.0 1 1 1 2 2 2 0 NTPase F-box-like_2 PF13013.4 001112425.2_53728001_2 - 0.095 12.6 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 F-box-like domain AAA_11 PF13086.4 001112425.2_53728001_2 - 0.24 11.0 9.5 1.9 8.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain Molybdopterin PF00384.20 001288388.1_48626001_1 - 2.8e-74 250.5 0.0 1.4e-73 248.2 0.0 1.8 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.4 001288388.1_48626001_1 - 1.8e-18 66.2 0.0 4.9e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.7 001288388.1_48626001_1 - 6.4e-16 57.5 0.1 1.5e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.9 001288388.1_48626001_1 - 7.9e-14 51.9 0.6 7.9e-14 51.9 0.6 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.25 001288388.1_48626001_1 - 5.5e-09 35.7 0.1 5.5e-09 35.7 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.20 001288388.1_48626001_1 - 0.0092 15.6 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain tRNA_anti-codon PF01336.23 001288388.1_48626001_1 - 0.072 13.0 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Fer4 PF00037.25 001288388.1_48626001_1 - 0.22 11.3 2.4 9.1 6.2 0.4 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain GCV_T PF01571.19 001288362.1_48623001_3 - 5e-88 294.7 0.0 6.1e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.9 001288362.1_48623001_3 - 4e-24 84.5 0.0 7.3e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain AAA PF00004.27 001288131.1_48623001_2 - 3.5e-44 150.3 0.0 9.2e-44 148.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.12 001288131.1_48623001_2 - 1.4e-08 34.7 1.1 4.7e-08 33.0 0.2 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001288131.1_48623001_2 - 3.2e-07 30.8 0.1 6.7e-05 23.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.12 001288131.1_48623001_2 - 9.8e-07 28.9 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.11 001288131.1_48623001_2 - 5e-05 22.5 0.1 0.00013 21.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.4 001288131.1_48623001_2 - 9.7e-05 22.5 1.9 0.0095 16.1 0.1 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.10 001288131.1_48623001_2 - 0.00025 20.3 0.0 0.0006 19.0 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.15 001288131.1_48623001_2 - 0.00057 19.6 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.4 001288131.1_48623001_2 - 0.0006 20.2 0.0 0.0016 18.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.4 001288131.1_48623001_2 - 0.00064 19.9 0.2 0.0015 18.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.20 001288131.1_48623001_2 - 0.0014 18.8 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.24 001288131.1_48623001_2 - 0.0019 17.8 0.3 0.17 11.4 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.19 001288131.1_48623001_2 - 0.002 17.4 0.1 0.004 16.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.11 001288131.1_48623001_2 - 0.0029 16.5 0.0 0.0054 15.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.4 001288131.1_48623001_2 - 0.0035 17.4 0.0 0.0097 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain TsaE PF02367.15 001288131.1_48623001_2 - 0.0042 16.9 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.4 001288131.1_48623001_2 - 0.005 16.7 0.0 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain EzrA PF06160.10 001288131.1_48623001_2 - 0.0051 14.9 0.9 0.0073 14.4 0.9 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Ada3 PF10198.7 001288131.1_48623001_2 - 0.0069 16.4 0.5 0.014 15.4 0.5 1.4 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 AAA_30 PF13604.4 001288131.1_48623001_2 - 0.0071 16.0 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.4 001288131.1_48623001_2 - 0.0071 16.0 0.1 0.016 14.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.4 001288131.1_48623001_2 - 0.0089 15.5 1.9 0.029 13.8 0.2 2.1 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.13 001288131.1_48623001_2 - 0.015 15.1 0.0 0.059 13.2 0.0 2.0 2 0 0 2 2 2 0 NTPase Parvo_NS1 PF01057.15 001288131.1_48623001_2 - 0.02 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.10 001288131.1_48623001_2 - 0.02 14.7 0.2 0.094 12.5 0.1 2.1 3 0 0 3 3 2 0 NACHT domain DUF3450 PF11932.6 001288131.1_48623001_2 - 0.022 13.9 0.6 0.055 12.6 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) AAA_3 PF07726.9 001288131.1_48623001_2 - 0.03 14.1 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.9 001288131.1_48623001_2 - 0.046 12.8 0.0 3 6.8 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.11 001288131.1_48623001_2 - 0.061 12.5 1.1 0.49 9.6 0.0 2.5 3 0 0 3 3 3 0 KaiC GrpE PF01025.17 001288131.1_48623001_2 - 0.084 12.4 0.6 0.86 9.1 0.1 2.1 2 0 0 2 2 2 0 GrpE ATPase_2 PF01637.16 001288131.1_48623001_2 - 0.084 12.6 1.3 1.9 8.2 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Prot_ATP_ID_OB PF16450.3 001288131.1_48623001_2 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB/ID domain AAA_11 PF13086.4 001288131.1_48623001_2 - 0.11 12.0 0.1 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain PHY PF00360.18 001287857.1_48627001_1 - 3.3e-60 202.4 0.0 5.3e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region PAS PF00989.23 001287857.1_48627001_1 - 2.7e-51 172.2 0.0 2.5e-24 85.3 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.9 001287857.1_48627001_1 - 2.7e-43 146.9 0.0 7.2e-43 145.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold GAF PF01590.24 001287857.1_48627001_1 - 8.2e-31 107.1 0.1 2.5e-30 105.6 0.1 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.24 001287857.1_48627001_1 - 4.4e-12 46.4 0.0 1.3e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.23 001287857.1_48627001_1 - 1.5e-11 44.0 0.8 6.7e-11 41.9 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.5 001287857.1_48627001_1 - 2.8e-11 43.5 0.1 0.00012 22.1 0.0 4.2 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.8 001287857.1_48627001_1 - 1.7e-08 34.5 0.0 4.6e-06 26.7 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.5 001287857.1_48627001_1 - 6.1e-06 26.0 0.0 0.017 15.0 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.10 001287857.1_48627001_1 - 0.00012 22.2 0.0 0.1 12.8 0.0 3.2 3 0 0 3 3 3 1 PAS fold Phosphorylase PF00343.18 001288199.1_48627001_3 - 5.6e-301 999.9 0.2 1.7e-168 562.1 0.0 2.0 2 0 0 2 2 2 2 Carbohydrate phosphorylase Ets PF00178.20 001288199.1_48627001_3 - 0.96 9.8 3.5 0.78 10.1 0.2 2.6 3 0 0 3 3 3 0 Ets-domain CPSF100_C PF13299.4 001288199.1_48627001_3 - 1.7 8.7 7.0 11 6.0 4.1 2.9 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal PDCD2_C PF04194.11 001288199.1_48627001_3 - 2.4 8.1 5.9 9.2 6.2 2.9 2.4 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Glyco_hydro_77 PF02446.15 001287852.1_48625001_2 - 1.5e-147 492.1 0.0 1.9e-147 491.8 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase DUF4808 PF16066.3 001287852.1_48625001_2 - 1.6 9.3 3.4 0.46 11.0 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) Porin_3 PF01459.20 001288205.1_48623001_2 - 7.7e-73 245.1 5.1 8.7e-73 245.0 5.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin TPT PF03151.14 001287896.1_48624001_1 - 2.8e-110 368.1 18.4 3.4e-110 367.8 18.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.18 001287896.1_48624001_1 - 2.7e-10 40.4 24.9 7.3e-07 29.3 6.6 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.9 001287896.1_48624001_1 - 1.1 8.2 18.7 6.5 5.7 18.7 1.9 1 1 0 1 1 1 0 UAA transporter family DUF2178 PF09946.7 001287896.1_48624001_1 - 1.3 9.0 5.0 0.43 10.6 0.5 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) Phosphorylase PF00343.18 001288189.1_48626001_3 - 0 1011.4 0.0 0 1011.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase FA_desaturase_2 PF03405.12 001288269.1_48624001_2 - 3.1e-153 509.3 0.0 3.6e-153 509.0 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.15 001288269.1_48624001_2 - 0.0063 16.8 0.1 1.1 9.5 0.1 2.5 2 0 0 2 2 2 2 Rubrerythrin Phenol_Hydrox PF02332.16 001288269.1_48624001_2 - 0.038 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase Ferritin PF00210.22 001288269.1_48624001_2 - 0.066 13.0 0.0 3.8 7.3 0.0 3.2 3 0 0 3 3 3 0 Ferritin-like domain PHY PF00360.18 001288455.1_48627001_1 - 8.9e-57 191.3 0.0 1.5e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region PAS PF00989.23 001288455.1_48627001_1 - 2.8e-47 159.3 0.0 2.1e-23 82.3 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.9 001288455.1_48627001_1 - 8e-39 132.5 0.1 1.6e-36 125.1 0.0 3.2 3 0 0 3 3 3 1 PAS fold GAF PF01590.24 001288455.1_48627001_1 - 2.6e-34 118.4 0.0 6.4e-34 117.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.24 001288455.1_48627001_1 - 2.1e-10 41.0 0.0 5.4e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.8 001288455.1_48627001_1 - 7.8e-09 35.6 0.0 3.2e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold HisKA PF00512.23 001288455.1_48627001_1 - 5.2e-08 32.7 0.1 4e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.5 001288455.1_48627001_1 - 8.6e-08 32.3 0.1 2e-05 24.6 0.0 3.2 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.5 001288455.1_48627001_1 - 3.9e-06 26.6 0.1 0.00078 19.3 0.0 3.1 3 0 0 3 3 3 1 PAS domain Porin_3 PF01459.20 001288225.1_48623001_3 - 1.3e-75 254.2 4.5 1.5e-75 254.0 4.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Alpha-amylase_C PF02806.16 001288254.1_48627001_1 - 1.2e-22 80.0 0.1 5.3e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.16 001288254.1_48627001_1 - 1.3e-18 66.9 0.1 3.1e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.22 001288254.1_48627001_1 - 4.2e-13 49.5 2.5 7.1e-11 42.1 0.2 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain GST_N PF02798.18 001111641.2_53723001_3 - 4.4e-25 87.7 0.0 7.5e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001111641.2_53723001_3 - 2.8e-19 69.1 0.0 5.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001111641.2_53723001_3 - 2.9e-19 69.0 0.1 4.5e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001111641.2_53723001_3 - 1.2e-14 54.3 0.0 1.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001111641.2_53723001_3 - 5.9e-10 38.8 0.5 1.3e-09 37.7 0.5 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001111641.2_53723001_3 - 6.5e-07 29.3 0.1 1.2e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.20 001301533.1_53724001_1 - 4.9e-93 312.3 0.0 5.7e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hist_deacetyl PF00850.17 001111549.2_53726001_1 - 4.6e-86 288.9 0.0 7.4e-86 288.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Sod_Cu PF00080.18 001320832.1_53722001_1 - 1.3e-47 161.4 4.1 1.7e-47 161.0 4.1 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Glyco_hydro_17 PF00332.16 001112264.2_53723001_2 - 6.5e-120 400.1 0.4 7.5e-120 399.9 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_19 PF00182.17 001353437.1_53723001_1 - 7.2e-57 192.8 9.5 1.7e-44 152.3 4.2 2.9 1 1 1 2 2 2 2 Chitinase class I Chitin_bind_1 PF00187.17 001353437.1_53723001_1 - 9.2e-10 38.7 19.3 9.2e-10 38.7 19.3 2.5 3 0 0 3 3 3 1 Chitin recognition protein HALZ PF02183.16 001315961.1_06922001_1 - 8.5e-16 57.7 4.0 1.5e-15 57.0 4.0 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Homeobox PF00046.27 001315961.1_06922001_1 - 1.1e-14 53.8 4.1 1.1e-14 53.8 4.1 2.0 2 1 1 3 3 3 1 Homeobox domain YjbH PF06082.9 001315961.1_06922001_1 - 0.0022 16.8 1.5 0.0026 16.6 1.5 1.0 1 0 0 1 1 1 1 Exopolysaccharide biosynthesis protein YbjH Homeobox_KN PF05920.9 001315961.1_06922001_1 - 0.0027 17.4 0.1 0.0075 16.0 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF2774 PF11242.6 001315961.1_06922001_1 - 0.05 13.7 1.0 0.27 11.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) HTH_23 PF13384.4 001315961.1_06922001_1 - 0.12 12.1 0.2 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1 PF01527.18 001315961.1_06922001_1 - 0.38 11.0 5.0 0.89 9.8 5.0 1.7 1 1 0 1 1 1 0 Transposase FlxA PF14282.4 001315961.1_06922001_1 - 0.43 10.5 6.2 0.14 12.0 0.4 2.2 2 0 0 2 2 2 0 FlxA-like protein ACCA PF03255.12 001315961.1_06922001_1 - 0.8 9.4 7.8 3.1 7.5 0.3 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit KASH_CCD PF14662.4 001315961.1_06922001_1 - 1.4 8.6 17.8 0.044 13.5 4.9 2.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-H PF05837.10 001315961.1_06922001_1 - 2.5 8.4 9.4 0.42 10.9 2.9 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) IncA PF04156.12 001315961.1_06922001_1 - 3.4 7.3 10.3 2.8 7.5 9.1 1.4 1 1 0 1 1 1 0 IncA protein Kinetocho_Slk19 PF12709.5 001315961.1_06922001_1 - 3.9 7.8 15.1 0.3 11.4 6.0 2.4 2 0 0 2 2 2 0 Central kinetochore-associated Pkinase PF00069.23 001315938.1_06923001_1 - 2.3e-65 220.5 0.0 2.6e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315938.1_06923001_1 - 8.3e-40 136.6 0.0 1.1e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001315938.1_06923001_1 - 7.6e-06 25.9 0.1 0.031 14.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.4 001315938.1_06923001_1 - 3e-05 23.3 0.0 9e-05 21.8 0.0 1.6 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.20 001315938.1_06923001_1 - 0.00084 18.9 0.1 0.0012 18.3 0.1 1.1 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.4 001315938.1_06923001_1 - 0.0082 15.7 0.0 3.4 7.1 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.18 001315938.1_06923001_1 - 0.04 13.4 0.5 1.9 7.9 0.2 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF3446 PF11928.6 001315938.1_06923001_1 - 1.9 8.7 14.5 1.2 9.4 5.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Pkinase PF00069.23 001315995.1_06923001_1 - 3.5e-70 236.2 0.0 4.6e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315995.1_06923001_1 - 4.7e-36 124.3 0.0 6.5e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315995.1_06923001_1 - 4.6e-18 65.0 0.1 1.1e-17 63.8 0.1 1.6 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315995.1_06923001_1 - 2.8e-09 36.6 0.0 1.2e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.12 001315995.1_06923001_1 - 0.0062 15.8 0.1 0.047 12.9 0.0 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.23 001315994.1_06923001_1 - 3.6e-72 242.8 0.0 4.7e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315994.1_06923001_1 - 7.2e-34 117.1 0.0 9.9e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315994.1_06923001_1 - 5.9e-20 71.1 0.7 1.1e-19 70.2 0.7 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315994.1_06923001_1 - 1.7e-09 37.3 0.0 6.6e-08 32.1 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001315994.1_06923001_1 - 0.0083 15.4 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001315994.1_06923001_1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FA_desaturase PF00487.22 001316165.1_06923001_1 - 8.2e-31 107.6 15.1 8.2e-31 107.6 15.1 1.3 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.6 001316165.1_06923001_1 - 4.1e-06 26.9 0.1 7.8e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Lyase_aromatic PF00221.17 001315686.1_06925001_2 - 1.1e-150 502.2 0.8 1.4e-150 501.9 0.8 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Calreticulin PF00262.16 001316226.1_06924001_1 - 3e-71 240.1 15.1 7.3e-50 169.7 4.0 2.2 1 1 1 2 2 2 2 Calreticulin family CDC45 PF02724.12 001316226.1_06924001_1 - 0.035 12.3 12.9 0.062 11.5 12.9 1.3 1 0 0 1 1 1 0 CDC45-like protein LolB PF03550.12 001316226.1_06924001_2 - 0.033 14.1 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Caleosin PF05042.11 001315834.1_06923001_2 - 7.7e-75 250.4 0.0 1e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein AP2 PF00847.18 001316168.1_06922001_1 - 6.5e-11 42.2 0.1 6.5e-11 42.2 0.1 1.8 2 0 0 2 2 2 1 AP2 domain IF4E PF01652.16 001316168.1_06922001_1 - 0.042 13.5 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E DUF5101 PF17031.3 001316168.1_06922001_1 - 0.078 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) UDPGT PF00201.16 001316062.1_06923001_1 - 2.9e-22 79.0 0.0 4.1e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ENOD40 PF08247.9 001316062.1_06923001_2 - 0.096 12.6 1.1 0.5 10.3 1.1 2.3 1 0 0 1 1 1 0 ENOD40 protein LEA_4 PF02987.14 001315725.1_06922001_2 - 1.3e-11 44.2 81.9 0.00015 21.6 8.5 5.6 2 1 3 5 5 5 5 Late embryogenesis abundant protein YtxH PF12732.5 001315725.1_06922001_2 - 0.00015 22.1 55.3 0.32 11.4 6.7 4.5 1 1 3 4 4 4 3 YtxH-like protein Apolipoprotein PF01442.16 001315725.1_06922001_2 - 0.0005 19.9 49.1 0.0022 17.8 49.1 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mitofilin PF09731.7 001315725.1_06922001_2 - 0.001 17.8 49.4 0.0013 17.5 49.4 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF883 PF05957.11 001315725.1_06922001_2 - 0.0035 17.8 50.7 0.98 9.9 15.8 4.1 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) TFIIA PF03153.11 001315725.1_06922001_2 - 8.9 6.0 48.0 13 5.5 48.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.3 001315725.1_06922001_2 - 9.3 3.1 33.0 11 2.9 33.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Myb_DNA-binding PF00249.29 001316227.1_06922001_1 - 4.8e-34 116.1 3.8 1.9e-16 59.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316227.1_06922001_1 - 3.3e-18 65.6 0.8 6.7e-11 42.1 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001316227.1_06922001_1 - 0.026 14.4 0.4 0.098 12.6 0.0 2.1 3 0 0 3 3 3 0 SLIDE FAM219A PF15260.4 001316227.1_06922001_1 - 0.053 13.8 2.6 0.11 12.7 2.6 1.6 1 1 0 1 1 1 0 Protein family FAM219A IQCJ-SCHIP1 PF15157.4 001316227.1_06922001_1 - 0.19 11.5 3.2 0.17 11.6 1.5 1.7 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Pkinase PF00069.23 001315885.1_06923001_1 - 1.3e-52 178.6 0.0 1.6e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315885.1_06923001_1 - 1.9e-31 109.2 0.0 2.6e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001315885.1_06923001_1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Myb_DNA-binding PF00249.29 001315899.1_06923001_2 - 5.5e-35 119.1 0.9 2.5e-18 65.8 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001315899.1_06923001_2 - 1.3e-28 98.9 0.8 1.9e-16 59.9 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001315899.1_06923001_2 - 0.00028 20.7 0.0 0.033 14.1 0.0 2.4 1 1 0 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.3 001315899.1_06923001_2 - 0.014 15.2 0.0 1.6 8.5 0.0 2.4 1 1 1 2 2 2 0 Myb DNA-binding like SOG2 PF10428.7 001315899.1_06923001_2 - 0.14 11.3 4.5 0.17 11.0 4.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein AP2 PF00847.18 001316287.1_06922001_1 - 2.5e-10 40.3 0.4 2.5e-10 40.3 0.4 2.0 3 0 0 3 3 3 1 AP2 domain WD40 PF00400.30 001316150.1_06923001_1 - 5.6e-08 33.2 5.1 0.071 13.9 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001316150.1_06923001_1 - 1.9e-05 24.8 0.1 0.0087 16.2 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain AhpC-TSA PF00578.19 001315637.1_06922001_1 - 4.1e-28 97.7 0.0 5.5e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001315637.1_06922001_1 - 7.2e-13 48.3 0.0 1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 001315637.1_06922001_1 - 1.2e-09 37.7 0.2 2.6e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.4 001315637.1_06922001_1 - 0.03 14.3 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Pkinase PF00069.23 001316046.1_06923001_1 - 2.8e-70 236.6 0.0 3.6e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316046.1_06923001_1 - 3.2e-40 137.9 0.0 4.3e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001316046.1_06923001_1 - 7.7e-15 54.7 0.0 2.2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001316046.1_06923001_1 - 5.7e-08 32.3 0.0 2.7e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.12 001316046.1_06923001_1 - 0.00027 20.2 0.1 0.0011 18.3 0.1 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001316046.1_06923001_1 - 0.0041 16.6 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.21 001316046.1_06923001_1 - 0.013 15.3 0.2 0.18 11.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Oleosin PF01277.15 001316097.1_06924001_2 - 1.7e-12 47.0 12.4 1.7e-12 47.0 12.4 1.5 2 0 0 2 2 2 1 Oleosin DUF481 PF04338.10 001316097.1_06924001_3 - 0.11 12.4 1.1 6.1 6.7 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF481 Secretin PF00263.19 001316097.1_06924001_3 - 0.24 10.9 18.5 0.58 9.6 3.8 3.0 1 1 2 3 3 3 0 Bacterial type II and III secretion system protein DUF5020 PF16412.3 001316097.1_06924001_3 - 1.2 8.9 6.2 10 5.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5020) Phage_BR0599 PF09356.8 001316097.1_06924001_3 - 1.9 8.8 3.7 19 5.6 0.1 3.0 2 1 1 3 3 3 0 Phage conserved hypothetical protein BR0599 E1_DerP2_DerF2 PF02221.13 001316097.1_06924001_3 - 2.8 8.3 8.5 34 4.7 0.5 3.9 1 1 3 4 4 4 0 ML domain Glyco_hydro_2 PF00703.19 001316097.1_06924001_3 - 3.9 8.0 16.4 11 6.6 1.1 3.4 2 1 1 3 3 3 0 Glycosyl hydrolases family 2 Pkinase PF00069.23 001316196.1_06923001_1 - 2.7e-73 246.5 0.0 3.6e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316196.1_06923001_1 - 3.4e-43 147.7 0.0 1.2e-42 145.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase NAF PF03822.12 001316196.1_06923001_1 - 1e-22 79.9 0.1 1.9e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001316196.1_06923001_1 - 2.5e-09 36.8 0.0 1.3e-08 34.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001316196.1_06923001_1 - 0.016 15.0 0.1 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.23 001316005.1_06923001_1 - 1.4e-73 247.4 0.0 2.3e-73 246.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316005.1_06923001_1 - 1.1e-35 123.1 0.0 1.6e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001316005.1_06923001_1 - 6.1e-23 80.6 0.5 1.2e-22 79.7 0.5 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001316005.1_06923001_1 - 2.2e-10 40.2 0.0 7.7e-10 38.4 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001316005.1_06923001_1 - 9.3e-05 21.7 0.2 0.0002 20.6 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001316005.1_06923001_1 - 0.0017 18.2 0.1 0.0056 16.5 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.18 001316005.1_06923001_1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase RRM_3 PF08777.9 001316005.1_06923001_1 - 0.016 15.1 0.3 0.053 13.4 0.3 1.9 1 0 0 1 1 1 0 RNA binding motif GvpO PF05800.9 001316005.1_06923001_1 - 0.14 12.0 0.4 0.33 10.8 0.4 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Chloroa_b-bind PF00504.19 001315642.1_06922001_1 - 5.1e-49 166.8 0.1 6.6e-49 166.4 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PhosphMutase PF10143.7 001315642.1_06922001_1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Myb_DNA-binding PF00249.29 001316142.1_06923001_2 - 1.2e-36 124.4 1.1 2.2e-19 69.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316142.1_06923001_2 - 1.1e-26 92.7 0.9 5.9e-17 61.5 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001316142.1_06923001_2 - 0.0011 18.9 0.0 0.88 9.5 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.3 001316142.1_06923001_2 - 0.0024 17.6 0.0 0.39 10.5 0.0 2.5 1 1 1 2 2 2 2 Myb DNA-binding like Pkinase PF00069.23 001315749.1_06923001_1 - 7.2e-73 245.1 0.0 9.2e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315749.1_06923001_1 - 3.9e-35 121.3 0.0 5.3e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315749.1_06923001_1 - 2.2e-19 69.3 0.3 4.3e-19 68.3 0.3 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315749.1_06923001_1 - 3.1e-09 36.5 0.0 3.5e-07 29.7 0.0 2.3 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.12 001315749.1_06923001_1 - 0.011 14.9 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001315749.1_06923001_1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.14 001315749.1_06923001_1 - 0.14 12.2 1.4 0.21 11.6 0.3 1.9 2 0 0 2 2 2 0 ABC1 family Sulfotransfer_1 PF00685.25 001315571.1_06923001_2 - 9.2e-71 238.3 0.0 1.3e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001315571.1_06923001_2 - 2.3e-06 28.0 0.0 0.00036 20.9 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family adh_short PF00106.23 001316189.1_06923001_3 - 9.1e-48 162.2 0.0 1.5e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001316189.1_06923001_3 - 2.2e-36 125.4 0.0 3.1e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001316189.1_06923001_3 - 1.3e-10 41.3 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.4 001316189.1_06923001_3 - 0.0065 16.3 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding IL17_R_N PF15037.4 001316189.1_06923001_3 - 0.069 12.0 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region Abhydrolase_3 PF07859.11 001315841.1_06923001_1 - 5.8e-59 199.3 0.0 7.3e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.26 001315841.1_06923001_1 - 1.1e-08 34.4 0.5 5.7e-08 32.0 0.5 1.8 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.5 001315841.1_06923001_1 - 0.0022 16.8 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.11 001315841.1_06923001_1 - 0.052 11.9 0.1 0.079 11.3 0.1 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.18 001315841.1_06923001_1 - 0.11 12.5 0.0 0.64 9.9 0.0 2.0 1 1 0 1 1 1 0 Thioesterase domain Say1_Mug180 PF10340.7 001315841.1_06923001_1 - 0.12 11.1 0.0 0.22 10.2 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase DUF2974 PF11187.6 001315841.1_06923001_1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pkinase PF00069.23 001315596.1_06923001_1 - 1e-71 241.3 0.0 1.3e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315596.1_06923001_1 - 3.9e-40 137.7 0.0 5.4e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315596.1_06923001_1 - 9.1e-23 80.1 0.1 1.7e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315596.1_06923001_1 - 3.7e-09 36.2 0.0 2.7e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001315596.1_06923001_1 - 0.044 13.6 0.2 0.16 11.7 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family YukC PF10140.7 001315596.1_06923001_1 - 0.14 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC 2OG-FeII_Oxy PF03171.18 001316140.1_06922001_1 - 1e-23 83.6 0.0 2.3e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001316140.1_06922001_1 - 9.3e-15 55.3 0.0 1.5e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pkinase PF00069.23 001316087.1_06923001_1 - 4.8e-71 239.1 0.0 1.3e-69 234.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316087.1_06923001_1 - 7.9e-40 136.6 0.0 3.7e-39 134.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase NAF PF03822.12 001316087.1_06923001_1 - 2.1e-16 59.7 0.2 4.5e-16 58.6 0.2 1.6 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001316087.1_06923001_1 - 1.7e-06 27.5 0.0 4.8e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.12 001316087.1_06923001_1 - 0.00015 21.0 0.0 0.00033 19.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001316087.1_06923001_1 - 0.0023 17.7 0.0 0.0053 16.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.9 001316087.1_06923001_1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF775 PF05603.10 001316087.1_06923001_1 - 0.046 13.1 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) ABC1 PF03109.14 001316087.1_06923001_1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.20 001316087.1_06923001_1 - 0.085 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family NCOA_u2 PF16665.3 001316087.1_06923001_3 - 2.2 8.5 7.3 8 6.7 6.7 2.1 1 1 1 2 2 2 0 Unstructured region on nuclear receptor coactivator protein Pkinase PF00069.23 001316217.1_06924001_1 - 1.5e-71 240.7 0.0 2.1e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316217.1_06924001_1 - 3e-37 128.2 0.0 4.2e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001316217.1_06924001_1 - 4.5e-24 84.3 0.1 8.3e-24 83.4 0.1 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001316217.1_06924001_1 - 6.4e-06 25.6 0.0 1.2e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.12 001316217.1_06924001_1 - 0.022 14.0 0.0 0.051 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IDH PF03971.12 001316217.1_06924001_1 - 0.066 11.5 0.0 0.092 11.0 0.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase APH PF01636.21 001316217.1_06924001_1 - 0.088 12.6 0.0 1.1 9.0 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family FBPase PF00316.18 001316063.1_06923001_3 - 1.7e-57 193.9 0.3 2.3e-57 193.5 0.3 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain UDPGT PF00201.16 001315569.1_06924001_3 - 5.5e-23 81.4 0.0 8.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAS PF03514.12 001315955.1_06924001_1 - 4.1e-134 447.1 0.0 5.1e-134 446.8 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family DELLA PF12041.6 001315955.1_06924001_1 - 7.1e-36 121.8 1.4 5.2e-35 119.0 0.2 2.7 2 1 0 2 2 2 1 Transcriptional regulator DELLA protein N terminal DUF3439 PF11921.6 001315955.1_06924001_1 - 0.067 13.0 1.5 0.13 12.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PDEase_I_N PF08499.10 001315955.1_06924001_1 - 0.16 11.7 0.0 0.51 10.1 0.0 1.8 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal PTN_MK_N PF05196.11 001315955.1_06924001_3 - 0.13 12.4 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain Myb_DNA-binding PF00249.29 001315697.1_06923001_1 - 3.8e-36 122.9 1.1 8.5e-19 67.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001315697.1_06923001_1 - 8.8e-26 89.8 0.5 3.5e-16 59.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001315697.1_06923001_1 - 0.015 15.0 0.0 0.38 10.5 0.0 2.3 1 1 1 2 2 2 0 Myb DNA-binding like SLIDE PF09111.8 001315697.1_06923001_1 - 0.064 13.2 0.0 4.1 7.3 0.0 2.4 1 1 1 2 2 2 0 SLIDE adh_short PF00106.23 001315914.1_06923001_1 - 4.2e-50 169.8 0.1 6.7e-50 169.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001315914.1_06923001_1 - 1e-37 129.8 0.1 1.4e-37 129.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001315914.1_06923001_1 - 1.3e-12 47.9 0.1 1.8e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.4 001315914.1_06923001_1 - 0.00054 19.8 0.1 0.0018 18.1 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.19 001315914.1_06923001_1 - 0.018 14.4 0.1 0.032 13.5 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF260 PF03195.12 001315908.1_06923001_2 - 1.7e-23 82.7 0.0 2.9e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF260 Glyco_hydro_28 PF00295.15 001316252.1_06924001_3 - 2e-100 335.9 26.2 2e-100 335.9 26.2 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.5 001316252.1_06924001_3 - 6.8e-10 39.1 17.9 1.3e-09 38.1 8.9 3.8 1 1 2 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.6 001316252.1_06924001_3 - 0.018 14.6 0.0 0.049 13.2 0.0 1.8 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase H_PPase PF03030.14 001315900.1_06925001_1 - 2e-259 862.5 37.8 2.3e-259 862.3 37.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF1980 PF09323.8 001315900.1_06925001_1 - 0.73 9.6 3.2 6.2 6.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Raffinose_syn PF05691.10 001315582.1_06927001_2 - 0 1241.1 0.4 0 1240.8 0.4 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Cellulose_synt PF03552.12 001316291.1_06927001_3 - 0 1351.3 0.0 0 1350.9 0.0 1.1 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001316291.1_06927001_3 - 1.4e-40 137.2 8.3 2.4e-40 136.4 8.3 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001316291.1_06927001_3 - 2e-08 34.2 0.1 2e-08 34.2 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001316291.1_06927001_3 - 6.1e-05 22.5 14.3 0.00012 21.7 14.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.14 001316291.1_06927001_3 - 0.0036 17.4 4.4 0.0086 16.1 4.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Glyco_tranf_2_3 PF13641.4 001316291.1_06927001_3 - 0.03 14.1 0.0 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF3242 PF11586.6 001316291.1_06927001_3 - 0.14 11.8 0.9 0.31 10.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Prok-RING_1 PF14446.4 001316291.1_06927001_3 - 0.45 10.4 11.8 0.94 9.3 7.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Chal_sti_synt_N PF00195.17 001315548.1_06923001_2 - 1.3e-118 394.2 0.0 2.6e-118 393.2 0.0 1.4 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.13 001315548.1_06923001_2 - 7.9e-72 240.1 0.0 1.3e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.8 001315548.1_06923001_2 - 1.2e-07 31.6 0.1 9e-07 28.9 0.0 2.4 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.10 001315548.1_06923001_2 - 9.6e-06 24.9 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.8 001315548.1_06923001_2 - 1.7e-05 24.4 0.2 3.9e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CinA PF02464.15 001315548.1_06923001_2 - 0.12 11.8 0.0 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 Competence-damaged protein ATP-sulfurylase PF01747.15 001315829.1_06924001_2 - 3.7e-64 216.0 0.0 4.9e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.4 001315829.1_06924001_2 - 1.7e-43 147.9 0.0 2.8e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain PP2C PF00481.19 001315853.1_06923001_1 - 4.3e-68 229.6 0.1 5.4e-68 229.3 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001315853.1_06923001_1 - 1.2e-05 24.9 0.0 2.9e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C FA_desaturase_2 PF03405.12 001315956.1_06924001_1 - 1.2e-157 523.8 0.0 1.4e-157 523.6 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.15 001315956.1_06924001_1 - 0.0031 17.8 0.1 0.6 10.4 0.1 2.5 2 0 0 2 2 2 2 Rubrerythrin p450 PF00067.20 001316228.1_06924001_1 - 1.6e-73 247.9 0.0 2e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Semialdhyde_dhC PF02774.16 001316228.1_06924001_1 - 0.18 11.7 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain MBOAT PF03062.17 001316272.1_06924001_1 - 2.5e-28 99.3 22.8 2.5e-28 99.3 22.8 2.0 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.4 001316272.1_06924001_1 - 2.9e-05 24.1 2.7 7.5e-05 22.8 2.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family 2OG-FeII_Oxy PF03171.18 001316250.1_06923001_3 - 1.8e-24 86.0 0.0 2.9e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001316250.1_06923001_3 - 5.2e-23 81.9 0.0 9.7e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pkinase_Tyr PF07714.15 001315709.1_06925001_1 - 1.1e-46 159.2 0.0 1.7e-46 158.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001315709.1_06925001_1 - 5.9e-44 150.3 0.0 7.9e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.4 001315709.1_06925001_1 - 0.0073 17.0 0.0 0.082 13.6 0.0 2.4 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain ABC1 PF03109.14 001315709.1_06925001_1 - 0.041 13.9 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC1 family SKG6 PF08693.8 001315709.1_06925001_1 - 0.043 13.1 0.8 0.08 12.2 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.14 001315709.1_06925001_1 - 0.19 10.3 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E WRKY PF03106.13 001316245.1_06922001_1 - 1.2e-24 86.3 0.8 3.1e-24 85.0 0.8 1.7 1 0 0 1 1 1 1 WRKY DNA -binding domain Peptidase_C1 PF00112.21 001315573.1_06923001_2 - 9.2e-80 267.7 3.6 1.4e-79 267.2 3.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001315573.1_06923001_2 - 8.1e-15 54.9 1.2 1.5e-14 54.0 1.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 001315573.1_06923001_2 - 0.00078 18.2 1.1 0.14 10.8 0.4 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Acyltransf_C PF16076.3 001316026.1_06924001_2 - 1.4e-22 79.5 0.0 2.6e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.19 001316026.1_06924001_2 - 2.9e-17 62.4 0.1 8.3e-17 60.9 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase HCO3_cotransp PF00955.19 001315719.1_06925001_1 - 5.7e-83 279.4 3.3 3.7e-36 125.0 2.1 3.1 2 1 1 3 3 3 3 HCO3- transporter family bZIP_1 PF00170.19 001315791.1_06922001_1 - 8.7e-13 48.0 13.5 1.9e-12 47.0 13.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001315791.1_06922001_1 - 1e-10 41.4 16.3 1.9e-10 40.5 16.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001315791.1_06922001_1 - 0.041 14.3 9.9 0.041 14.3 9.9 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor AhpC-TSA PF00578.19 001316004.1_06922001_1 - 9.7e-40 135.2 0.0 1.3e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.8 001316004.1_06922001_1 - 3.7e-14 52.5 0.0 5.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.7 001316004.1_06922001_1 - 3.7e-11 42.6 0.1 6.6e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin WRKY PF03106.13 001315868.1_06922001_1 - 1.2e-23 83.1 0.4 1.2e-23 83.1 0.4 2.0 2 0 0 2 2 2 1 WRKY DNA -binding domain MIP PF00230.18 001316109.1_06923001_1 - 9.7e-77 257.6 19.4 1.2e-76 257.3 19.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF992 PF06186.9 001316109.1_06923001_1 - 0.093 12.4 3.9 0.42 10.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF992) Acyltransf_C PF16076.3 001316166.1_06924001_1 - 1.4e-22 79.5 0.0 3.9e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.19 001316166.1_06924001_1 - 3.3e-17 62.2 0.0 6.8e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase K-box PF01486.15 001315773.1_06922001_1 - 3.9e-27 94.1 7.7 7.8e-27 93.2 7.7 1.4 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001315773.1_06922001_1 - 2.3e-26 90.9 0.3 4e-26 90.1 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TPR_MLP1_2 PF07926.10 001315773.1_06922001_1 - 0.15 12.0 2.9 9.5 6.2 1.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1192 PF06698.9 001315773.1_06922001_1 - 0.23 11.4 0.9 1.6 8.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) GIT_CC PF16559.3 001315773.1_06922001_1 - 1.5 8.8 4.7 4.3 7.3 1.4 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2721 PF11026.6 001315773.1_06922001_1 - 3.2 7.5 4.4 5.6 6.7 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) bZIP_2 PF07716.13 001315773.1_06922001_1 - 4.7 7.2 11.6 0.54 10.3 2.6 3.0 3 1 0 3 3 3 0 Basic region leucine zipper Pkinase PF00069.23 001316300.1_06923001_1 - 7.9e-70 235.1 0.0 1.1e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316300.1_06923001_1 - 6.8e-31 107.4 0.0 1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001316300.1_06923001_1 - 2.2e-05 23.8 0.0 0.00022 20.5 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001316300.1_06923001_1 - 0.0028 16.9 0.1 0.0044 16.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDP-OH_P_transf PF01066.19 001316223.1_06924001_2 - 1.8e-12 47.7 0.1 1.8e-12 47.7 0.1 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Prominin PF05478.9 001316223.1_06924001_2 - 0.027 12.3 3.3 0.037 11.9 3.3 1.1 1 0 0 1 1 1 0 Prominin CDP-OH_P_transf PF01066.19 001316223.1_06924001_3 - 1.2 9.8 3.9 2.7 8.7 3.8 1.7 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase AMP-binding PF00501.26 001315952.1_06925001_1 - 1.2e-107 360.0 0.0 1.4e-107 359.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001315952.1_06925001_1 - 0.0002 22.2 0.4 0.00073 20.3 0.0 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Apo-VLDL-II PF05418.9 001315952.1_06925001_1 - 0.11 12.9 0.0 0.35 11.3 0.0 1.8 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) Aa_trans PF01490.16 001316066.1_06924001_2 - 1.6e-119 399.1 23.0 2.2e-119 398.7 23.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.23 001315854.1_06923001_1 - 2.5e-67 226.9 0.0 4.3e-67 226.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315854.1_06923001_1 - 4.7e-41 140.6 0.0 7.1e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315854.1_06923001_1 - 4e-15 55.6 0.2 8.1e-15 54.6 0.2 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315854.1_06923001_1 - 3.6e-08 32.9 0.0 6.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.20 001315854.1_06923001_1 - 2e-05 24.2 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.12 001315854.1_06923001_1 - 0.00017 20.9 0.1 0.00027 20.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001315854.1_06923001_1 - 0.0053 16.6 0.0 0.24 11.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Integrase_DNA PF02920.13 001315854.1_06923001_3 - 0.02 14.5 1.4 0.032 13.8 1.4 1.3 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Snf7 PF03357.19 001316293.1_06923001_1 - 3.7e-15 55.8 12.0 5.7e-15 55.2 12.0 1.2 1 0 0 1 1 1 1 Snf7 Imm6 PF14434.4 001316293.1_06923001_1 - 0.027 14.3 0.6 0.068 13.0 0.6 1.7 1 0 0 1 1 1 0 Immunity protein Imm6 Herpes_BLRF2 PF05812.10 001316293.1_06923001_1 - 0.044 13.8 1.3 0.044 13.8 1.3 2.4 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DnaB_C PF03796.13 001316293.1_06923001_1 - 0.085 12.0 2.9 0.18 11.0 2.9 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_23 PF13476.4 001316293.1_06923001_1 - 0.15 12.4 3.1 0.25 11.7 3.1 1.4 1 0 0 1 1 1 0 AAA domain WRKY PF03106.13 001316098.1_06923001_1 - 3.7e-50 168.0 16.0 1.5e-25 89.2 2.8 2.8 3 0 0 3 3 3 2 WRKY DNA -binding domain FLYWCH PF04500.14 001316098.1_06923001_1 - 0.09 12.8 2.2 1.1 9.3 0.3 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain Roc PF08477.11 001316098.1_06923001_1 - 0.14 12.3 1.2 0.32 11.1 1.2 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Kelch_3 PF13415.4 001316025.1_06925001_1 - 9e-36 121.3 9.2 9.2e-12 44.8 0.0 6.5 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.4 001316025.1_06925001_1 - 9.5e-31 104.9 3.1 9.5e-07 28.8 0.0 6.6 4 2 2 6 6 6 5 Kelch motif Kelch_4 PF13418.4 001316025.1_06925001_1 - 2.9e-29 100.6 13.8 6.9e-09 35.4 0.0 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.4 001316025.1_06925001_1 - 1.2e-25 88.9 1.4 8.6e-05 22.3 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.13 001316025.1_06925001_1 - 1.8e-23 81.4 6.8 3e-06 26.9 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.23 001316025.1_06925001_1 - 3.5e-23 80.8 9.5 1.4e-07 30.9 0.1 6.8 7 0 0 7 7 7 5 Kelch motif ACBP PF00887.17 001316025.1_06925001_1 - 5.9e-19 68.0 0.0 1.4e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein CALCOCO1 PF07888.9 001316025.1_06925001_1 - 0.00036 19.1 15.2 0.00053 18.6 15.2 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.12 001316025.1_06925001_1 - 0.027 14.1 20.6 0.043 13.5 20.6 1.2 1 0 0 1 1 1 0 IncA protein Spc42p PF11544.6 001316025.1_06925001_1 - 0.033 14.0 2.7 0.09 12.6 2.7 1.7 1 0 0 1 1 1 0 Spindle pole body component Spc42p Fez1 PF06818.13 001316025.1_06925001_1 - 0.092 13.1 12.2 0.17 12.2 12.2 1.3 1 0 0 1 1 1 0 Fez1 Rootletin PF15035.4 001316025.1_06925001_1 - 0.79 9.6 15.5 1.3 8.9 15.5 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF724 PF05266.12 001316025.1_06925001_1 - 1.1 9.0 8.7 1.9 8.2 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MCU PF04678.11 001316025.1_06925001_1 - 1.5 8.8 3.7 3.1 7.8 3.7 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4407 PF14362.4 001316025.1_06925001_1 - 7.6 5.7 12.3 12 5.0 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.13 001316025.1_06925001_1 - 8.2 5.8 9.9 13 5.1 9.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit G-alpha PF00503.18 001315630.1_06923001_1 - 6.5e-97 324.7 1.7 7.9e-97 324.4 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001315630.1_06923001_1 - 1.8e-11 43.7 0.2 1.6e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001315630.1_06923001_1 - 0.046 12.9 0.9 4.7 6.4 0.0 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.9 001315630.1_06923001_1 - 0.05 12.7 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.25 001315630.1_06923001_1 - 0.065 12.6 0.2 0.95 8.8 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.11 001315630.1_06923001_1 - 0.068 13.3 0.2 3.2 7.9 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.4 001315630.1_06923001_1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.4 001315630.1_06923001_1 - 0.15 11.5 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Pkinase_Tyr PF07714.15 001315930.1_06923001_1 - 2.3e-69 233.4 0.0 3.2e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001315930.1_06923001_1 - 1.1e-56 192.1 0.0 1.6e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.4 001315930.1_06923001_1 - 0.0073 15.5 0.0 0.071 12.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001315930.1_06923001_1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family 3HCDH_N PF02737.16 001315691.1_06925001_3 - 1.4e-61 207.4 0.2 2.1e-61 206.8 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.18 001315691.1_06925001_3 - 4e-39 134.3 0.0 7.5e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.20 001315691.1_06925001_3 - 6.6e-27 93.8 0.0 9.5e-21 74.1 0.1 2.8 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.3 001315691.1_06925001_3 - 3.8e-23 82.4 0.0 1.5e-22 80.5 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase F420_oxidored PF03807.15 001315691.1_06925001_3 - 0.074 13.5 0.5 0.19 12.2 0.5 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.12 001315691.1_06925001_3 - 0.089 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_3 PF00202.19 001316290.1_06924001_1 - 1.2e-120 402.8 0.0 1.4e-120 402.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.19 001316290.1_06924001_1 - 8.8e-06 25.0 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.19 001316290.1_06924001_1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.15 001316290.1_06924001_1 - 0.16 11.1 0.0 1 8.5 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cellulose_synt PF03552.12 001315544.1_06927001_2 - 0 1365.0 0.0 0 1364.3 0.0 1.3 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001315544.1_06927001_2 - 4.4e-34 116.3 9.5 9e-34 115.3 9.5 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001315544.1_06927001_2 - 9.2e-07 28.8 0.5 9.2e-07 28.8 0.5 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001315544.1_06927001_2 - 0.001 18.6 15.7 0.0024 17.4 15.7 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.14 001315544.1_06927001_2 - 0.27 11.3 6.3 0.72 10.0 6.3 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.4 001315544.1_06927001_2 - 0.66 9.8 16.8 0.78 9.6 8.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 ICL PF00463.19 001315846.1_06924001_1 - 1.7e-270 897.9 0.5 1.9e-270 897.7 0.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.4 001315846.1_06924001_1 - 3e-10 39.8 0.1 1.5e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase CN_hydrolase PF00795.20 001316303.1_06923001_2 - 2.3e-70 236.8 0.0 2.8e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase WD40 PF00400.30 001316247.1_06924001_3 - 2.8e-27 94.3 8.7 3.3e-07 30.7 0.6 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001316247.1_06924001_3 - 1.2e-16 60.7 4.7 1.6e-07 31.4 0.1 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001316247.1_06924001_3 - 4.9e-06 25.6 1.2 0.0016 17.4 0.6 3.6 1 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Pro_dh PF01619.16 001316146.1_06923001_1 - 2.2e-77 260.4 0.0 3.1e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase adh_short_C2 PF13561.4 001316251.1_06923001_2 - 3.2e-53 180.5 1.7 6.6e-50 169.7 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001316251.1_06923001_2 - 6.1e-10 38.7 0.1 4.4e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Enoyl_reductase PF12241.6 001316251.1_06923001_2 - 0.0037 16.5 0.1 0.39 9.9 0.0 2.2 2 0 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region Linker_histone PF00538.17 001316094.1_06922001_2 - 1.3e-08 34.9 0.1 2.1e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family AT_hook PF02178.17 001316094.1_06922001_2 - 0.00046 19.6 57.1 0.18 11.6 7.7 4.7 4 0 0 4 4 4 4 AT hook motif RST PF12174.6 001315959.1_06924001_1 - 2.7e-26 91.2 0.1 3e-25 87.8 0.0 2.2 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain PARP PF00644.18 001315959.1_06924001_1 - 7.6e-08 32.1 0.0 2.3e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Iso_dh PF00180.18 001315942.1_06923001_1 - 1.3e-78 264.5 0.0 1.7e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.23 001316213.1_06923001_1 - 8.3e-72 241.6 0.0 1.1e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316213.1_06923001_1 - 2.6e-39 134.9 0.0 4e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001316213.1_06923001_1 - 1.3e-18 66.7 0.4 2.5e-18 65.8 0.4 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001316213.1_06923001_1 - 4.5e-06 26.1 0.0 6e-05 22.4 0.0 2.2 1 1 0 2 2 2 1 Kinase-like KA1 PF02149.17 001316213.1_06923001_1 - 0.003 17.2 0.0 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.12 001316213.1_06923001_1 - 0.0066 15.7 0.1 0.012 14.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001316213.1_06923001_1 - 0.089 12.6 0.1 0.23 11.2 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Bacteriocin_II PF01721.16 001316213.1_06923001_3 - 0.022 14.7 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 Class II bacteriocin Pkinase PF00069.23 001316222.1_06923001_1 - 3.8e-76 255.8 0.0 6.2e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001316222.1_06923001_1 - 4.3e-33 110.2 11.7 3.1e-08 32.5 0.1 4.6 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001316222.1_06923001_1 - 5e-28 98.0 0.0 8.4e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.4 001316222.1_06923001_1 - 9.9e-27 90.4 7.8 1.4e-07 30.7 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001316222.1_06923001_1 - 2.2e-25 88.8 3.8 1.1e-12 48.1 1.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001316222.1_06923001_1 - 3.9e-25 86.1 8.3 2.3e-06 26.7 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001316222.1_06923001_1 - 7.1e-21 73.6 12.3 2.1e-08 33.7 0.2 4.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.5 001316222.1_06923001_1 - 4.3e-09 36.1 1.3 0.0018 18.0 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001316222.1_06923001_1 - 7e-08 32.5 0.3 0.0024 18.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.12 001316222.1_06923001_1 - 2.7e-05 23.5 0.1 5e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.7 001316222.1_06923001_1 - 8.5e-05 22.7 0.3 0.16 12.2 0.2 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.4 001316222.1_06923001_1 - 0.00015 21.1 0.0 0.00045 19.5 0.0 1.8 2 1 0 2 2 2 1 Kinase-like APH PF01636.21 001316222.1_06923001_1 - 0.0015 18.4 0.0 0.27 11.0 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_11 PF08976.9 001316222.1_06923001_1 - 0.021 15.6 0.1 6.1 7.6 0.0 2.6 2 1 1 3 3 2 0 EF-hand domain PMBR PF09373.8 001316222.1_06923001_1 - 0.029 14.4 0.3 1.2 9.2 0.0 3.6 4 0 0 4 4 4 0 Pseudomurein-binding repeat EFhand_Ca_insen PF08726.8 001316222.1_06923001_1 - 0.038 13.9 0.0 5.4 7.1 0.1 2.5 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Caleosin PF05042.11 001316222.1_06923001_1 - 0.18 11.6 0.7 36 4.1 0.0 3.1 3 1 1 4 4 4 0 Caleosin related protein Pkinase PF00069.23 001315976.1_06924001_1 - 3.1e-73 246.3 0.0 4.4e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001315976.1_06924001_1 - 6.1e-28 94.1 15.6 3.1e-08 32.5 0.5 4.6 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001315976.1_06924001_1 - 7.1e-28 97.5 0.0 1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001315976.1_06924001_1 - 4.8e-23 81.3 5.8 4.3e-11 43.0 3.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001315976.1_06924001_1 - 1e-19 68.6 10.4 1.8e-05 24.2 0.1 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.4 001315976.1_06924001_1 - 2.3e-14 52.7 13.8 5.2e-07 29.2 0.8 4.4 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.4 001315976.1_06924001_1 - 2.7e-14 51.8 11.7 0.00021 20.5 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.5 001315976.1_06924001_1 - 6.7e-06 25.9 2.5 0.019 14.8 0.2 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.4 001315976.1_06924001_1 - 1.5e-05 24.4 0.0 0.0016 17.6 0.0 3.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001315976.1_06924001_1 - 7.5e-05 22.0 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.4 001315976.1_06924001_1 - 0.0025 18.0 0.5 1 9.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain APH PF01636.21 001315976.1_06924001_1 - 0.014 15.2 0.0 0.66 9.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.15 001315871.1_06923001_1 - 1.6e-51 175.0 0.0 2.3e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001315871.1_06923001_1 - 1.8e-42 145.4 0.0 2.5e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.5 001315871.1_06923001_1 - 1.4e-11 44.7 0.0 3.1e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.28 001315871.1_06923001_1 - 9.1e-11 41.6 0.3 8e-09 35.4 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.4 001315871.1_06923001_1 - 9.5e-11 41.6 0.2 2.8e-10 40.1 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.4 001315871.1_06923001_1 - 1.3e-10 41.5 0.1 1.8e-08 34.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001315871.1_06923001_1 - 5.9e-07 29.2 0.0 0.00014 21.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat APH PF01636.21 001315871.1_06923001_1 - 0.091 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family CBFB_NFYA PF02045.13 001315934.1_06923001_1 - 1.3e-27 96.1 8.9 2.5e-27 95.2 8.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ras PF00071.20 001315880.1_06922001_2 - 1.6e-61 206.5 0.8 2.1e-61 206.1 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001315880.1_06922001_2 - 1.4e-33 115.5 0.1 2.5e-33 114.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001315880.1_06922001_2 - 6.3e-16 58.2 0.1 8.9e-16 57.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001315880.1_06922001_2 - 6.2e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001315880.1_06922001_2 - 0.00013 21.5 0.3 0.00082 18.8 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001315880.1_06922001_2 - 0.0079 15.5 0.1 0.095 12.0 0.1 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001315880.1_06922001_2 - 0.017 14.3 0.0 0.029 13.6 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.14 001315880.1_06922001_2 - 0.04 13.7 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Oxidored_molyb PF00174.17 001316119.1_06926001_3 - 1.9e-56 190.2 0.0 2.9e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.14 001316119.1_06926001_3 - 2.6e-55 186.1 0.2 4.6e-55 185.3 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.22 001316119.1_06926001_3 - 2.4e-35 120.7 0.0 4.6e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.19 001316119.1_06926001_3 - 5.2e-32 110.6 0.0 1.2e-31 109.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.26 001316119.1_06926001_3 - 4.9e-24 84.1 0.0 1.2e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.10 001316119.1_06926001_3 - 0.088 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Lipase_GDSL PF00657.20 001316006.1_06923001_1 - 5e-24 85.3 0.2 6.6e-24 84.9 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pkinase PF00069.23 001316045.1_06925001_1 - 5.2e-73 245.5 0.0 6.9e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316045.1_06925001_1 - 4.9e-48 163.5 0.0 6.9e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001316045.1_06925001_1 - 6.1e-09 35.5 0.0 1.1e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Glyoxalase PF00903.23 001315759.1_06922001_1 - 1.5e-36 125.3 0.0 1.7e-22 79.8 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.4 001315759.1_06922001_1 - 2.2e-16 60.0 0.0 6e-09 36.0 0.0 2.4 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.4 001315759.1_06922001_1 - 3.7e-06 27.1 0.0 0.018 15.0 0.0 3.7 3 1 0 3 3 3 1 Glyoxalase-like domain CppA_N PF14506.4 001315759.1_06922001_1 - 8.4e-06 25.7 0.1 0.14 12.1 0.0 2.8 3 0 0 3 3 3 2 CppA N-terminal TPR_7 PF13176.4 001315759.1_06922001_1 - 0.0021 17.8 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.26 001315759.1_06922001_1 - 0.0069 16.0 0.0 0.1 12.3 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.4 001315759.1_06922001_1 - 0.015 15.4 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.15 001315759.1_06922001_1 - 0.034 14.1 0.1 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase_2 PF12681.5 001315759.1_06922001_1 - 0.11 12.3 0.0 22 4.9 0.0 3.0 3 1 0 3 3 3 0 Glyoxalase-like domain Pkinase_Tyr PF07714.15 001315904.1_06923001_1 - 2.2e-66 223.7 0.0 2.8e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001315904.1_06923001_1 - 3.9e-59 200.0 0.0 5.2e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.4 001315904.1_06923001_1 - 1e-08 35.4 0.5 8.3e-06 26.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001315904.1_06923001_1 - 2e-08 34.5 0.1 1.6e-07 31.7 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001315904.1_06923001_1 - 9.5e-07 28.9 0.1 3.3e-06 27.2 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.4 001315904.1_06923001_1 - 1.2e-06 28.2 0.0 2.3e-05 24.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.28 001315904.1_06923001_1 - 8.3e-06 25.9 0.0 6.8e-05 23.0 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat APH PF01636.21 001315904.1_06923001_1 - 0.00016 21.5 0.4 0.065 13.0 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family AMP-binding PF00501.26 001315957.1_06924001_2 - 3e-93 312.6 0.0 3.6e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001315957.1_06924001_2 - 2.6e-24 85.9 0.3 5.2e-24 84.9 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SRF-TF PF00319.16 001316034.1_06922001_1 - 1.1e-25 88.7 0.2 2e-25 87.9 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001316034.1_06922001_1 - 6.8e-16 58.1 12.7 1.3e-15 57.3 12.7 1.4 1 0 0 1 1 1 1 K-box region CO_dh PF02552.14 001316034.1_06922001_1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit PTS_IIA PF02255.14 001316034.1_06922001_1 - 0.11 12.4 0.7 6.5 6.7 0.2 2.6 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF2390 PF09523.8 001316034.1_06922001_1 - 4 7.7 8.1 1.3 9.3 2.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2390) Cytokin-bind PF09265.8 001315905.1_06924001_1 - 1.5e-113 378.8 0.3 1.8e-113 378.5 0.3 1.1 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 001315905.1_06924001_1 - 1.4e-19 70.1 0.1 2.8e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.23 001315828.1_06922001_1 - 5.1e-49 166.9 0.0 6.2e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315828.1_06922001_1 - 7.4e-36 123.6 0.1 9.1e-36 123.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001315828.1_06922001_1 - 0.095 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BCS1_N PF08740.9 001315828.1_06922001_1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 BCS1 N terminal NAM PF02365.13 001315717.1_06922001_1 - 1.3e-28 99.5 0.5 1.3e-28 99.5 0.5 1.5 2 0 0 2 2 2 1 No apical meristem (NAM) protein Actin PF00022.17 001315560.1_06923001_2 - 5.5e-146 486.2 0.0 1.8e-145 484.5 0.0 1.7 1 1 0 1 1 1 1 Actin FBPase PF00316.18 001315812.1_06923001_3 - 3.6e-57 192.8 0.5 5.1e-57 192.3 0.5 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Pkinase PF00069.23 001315604.1_06923001_1 - 5.9e-63 212.5 0.0 7e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315604.1_06923001_1 - 1.7e-35 122.5 0.0 2.2e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001315604.1_06923001_1 - 0.0047 16.1 0.1 0.041 13.1 0.1 2.3 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.9 001315604.1_06923001_1 - 0.015 14.2 0.1 0.036 13.0 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.21 001315604.1_06923001_1 - 0.026 14.3 0.2 0.29 10.9 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.20 001315604.1_06923001_1 - 0.088 12.3 0.3 0.13 11.7 0.3 1.3 1 0 0 1 1 1 0 RIO1 family HAD PF12710.5 001315768.1_06924001_1 - 3.2e-13 50.4 0.0 4.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.19 001315768.1_06924001_1 - 2.6e-06 27.0 0.0 6.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase SPX PF03105.17 001315901.1_06922001_2 - 4.5e-20 72.8 7.3 6.1e-09 36.2 0.1 3.1 1 1 2 3 3 3 3 SPX domain Asparaginase_2 PF01112.16 001315901.1_06922001_2 - 0.2 10.6 0.1 0.31 9.9 0.1 1.2 1 0 0 1 1 1 0 Asparaginase Pkinase PF00069.23 001315872.1_06923001_1 - 3.1e-74 249.6 0.0 4e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315872.1_06923001_1 - 2.4e-40 138.3 0.0 3.4e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315872.1_06923001_1 - 1.5e-21 76.2 0.0 4e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315872.1_06923001_1 - 2.2e-09 36.9 0.0 9.6e-09 34.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001315872.1_06923001_1 - 0.0084 15.4 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lipoprotein_16 PF03923.11 001315872.1_06923001_1 - 0.074 12.6 0.0 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized lipoprotein APH PF01636.21 001315872.1_06923001_1 - 0.24 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family 2OG-FeII_Oxy PF03171.18 001315916.1_06922001_1 - 2.6e-22 79.1 0.0 5.9e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001315916.1_06922001_1 - 2.3e-15 57.2 0.0 4.9e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal K-box PF01486.15 001315906.1_06922001_1 - 1.5e-27 95.4 7.5 3.5e-27 94.3 7.5 1.6 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001315906.1_06922001_1 - 3.5e-26 90.3 0.2 5.8e-26 89.6 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AKAP2_C PF15304.4 001315906.1_06922001_1 - 0.015 14.5 0.5 0.018 14.2 0.5 1.3 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus DUF1192 PF06698.9 001315906.1_06922001_1 - 0.22 11.5 0.9 1.4 8.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF2721 PF11026.6 001315906.1_06922001_1 - 2.8 7.7 4.1 6.1 6.6 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) WRKY PF03106.13 001315558.1_06922001_1 - 2.3e-25 88.6 1.2 5e-25 87.5 1.2 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain FAM176 PF14851.4 001315558.1_06922001_1 - 0.79 9.3 3.4 0.49 9.9 0.2 2.0 2 0 0 2 2 2 0 FAM176 family TLP-20 PF06088.9 001315558.1_06922001_1 - 10 5.9 8.1 7.2 6.3 0.8 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) K-box PF01486.15 001315943.1_06922001_1 - 3.7e-29 100.6 9.4 7e-29 99.7 9.4 1.4 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001315943.1_06922001_1 - 7.8e-27 92.4 0.8 2e-26 91.0 0.2 2.0 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF972 PF06156.11 001315943.1_06922001_1 - 0.0073 16.8 6.2 0.023 15.2 2.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF972) Speriolin_C PF15059.4 001315943.1_06922001_1 - 0.019 15.0 0.7 0.039 14.0 0.1 1.7 1 1 0 1 1 1 0 Speriolin C-terminus Proteasome_A_N PF10584.7 001315943.1_06922001_1 - 0.068 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature TCTP PF00838.15 001315943.1_06922001_1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.0 2 0 0 2 2 2 0 Translationally controlled tumour protein DUF3393 PF11873.6 001315943.1_06922001_1 - 1.2 8.7 8.0 0.22 11.1 3.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3393) bZIP_1 PF00170.19 001315943.1_06922001_1 - 1.4 9.0 14.1 0.45 10.5 4.3 3.0 2 1 0 2 2 2 0 bZIP transcription factor DUF3450 PF11932.6 001315943.1_06922001_1 - 2 7.5 10.6 1.3 8.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HAUS6_N PF14661.4 001315943.1_06922001_1 - 4.3 6.8 10.2 5.4 6.4 9.7 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TSC22 PF01166.16 001315943.1_06922001_1 - 5.7 7.2 10.1 1.1 9.4 0.8 3.1 2 1 0 3 3 3 0 TSC-22/dip/bun family DUF2423 PF10338.7 001315943.1_06922001_2 - 0.049 13.7 3.0 0.15 12.1 3.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) DUF3611 PF12263.6 001316186.1_06922001_1 - 2.8e-54 183.5 3.8 3.5e-54 183.2 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Sdh_cyt PF01127.20 001316186.1_06922001_1 - 0.77 9.7 5.9 0.13 12.2 1.2 1.9 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Cellulose_synt PF03552.12 001315941.1_06927001_1 - 0 1353.6 0.0 0 1353.0 0.0 1.3 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001315941.1_06927001_1 - 9.7e-17 60.7 5.1 9.7e-17 60.7 5.1 2.0 2 0 0 2 2 2 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001315941.1_06927001_1 - 1.7e-06 28.0 0.7 1.7e-06 28.0 0.7 3.2 4 0 0 4 4 4 1 Glycosyl transferase family group 2 FYVE_2 PF02318.14 001315941.1_06927001_1 - 0.037 14.1 4.0 0.091 12.8 4.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_4 PF14570.4 001315941.1_06927001_1 - 0.047 13.3 9.3 0.1 12.2 9.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NOB1_Zn_bind PF08772.9 001315941.1_06927001_1 - 0.052 13.6 1.1 0.53 10.4 1.5 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Glyco_tranf_2_3 PF13641.4 001315941.1_06927001_1 - 0.13 12.0 0.0 1.1 8.9 0.0 2.4 3 0 0 3 3 3 0 Glycosyltransferase like family 2 zf-RRN7 PF11781.6 001315941.1_06927001_1 - 0.56 9.8 4.7 0.88 9.2 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GTP_EFTU PF00009.25 001315606.1_06923001_1 - 1.5e-53 181.1 0.0 2.8e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001315606.1_06923001_1 - 1.7e-38 131.2 0.0 3.7e-38 130.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001315606.1_06923001_1 - 1.3e-13 51.0 0.7 2.7e-13 50.0 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001315606.1_06923001_1 - 0.00097 19.1 0.2 0.0041 17.1 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001315606.1_06923001_1 - 0.0071 16.2 0.5 0.021 14.7 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 SRPRB PF09439.8 001315606.1_06923001_1 - 0.019 14.3 0.1 0.24 10.7 0.1 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.4 001315606.1_06923001_1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.23 001315917.1_06923001_1 - 1.3e-72 244.3 0.0 2.2e-72 243.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315917.1_06923001_1 - 2.9e-36 125.0 0.0 4.6e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315917.1_06923001_1 - 6.6e-20 70.9 0.0 1.3e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315917.1_06923001_1 - 1.1e-09 37.9 0.0 6.7e-08 32.1 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001315917.1_06923001_1 - 0.0033 16.7 0.0 0.0073 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KA1 PF02149.17 001315917.1_06923001_1 - 0.0044 16.6 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Seadorna_VP7 PF07387.9 001315917.1_06923001_1 - 0.057 12.3 0.0 0.31 9.9 0.0 2.0 2 0 0 2 2 2 0 Seadornavirus VP7 ABC1 PF03109.14 001315917.1_06923001_1 - 0.06 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 ABC1 family APH PF01636.21 001315917.1_06923001_1 - 0.079 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NusA_N PF08529.9 001315917.1_06923001_1 - 0.32 11.2 3.6 0.23 11.7 1.0 2.0 2 0 0 2 2 2 0 NusA N-terminal domain HCO3_cotransp PF00955.19 001316102.1_06925001_1 - 9.6e-84 282.0 4.8 6e-36 124.3 2.6 3.1 2 1 1 3 3 3 3 HCO3- transporter family Amino_oxidase PF01593.22 001316264.1_06924001_1 - 1.2e-79 268.6 0.0 1.4e-79 268.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001316264.1_06924001_1 - 4.9e-15 55.4 0.1 1e-14 54.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001316264.1_06924001_1 - 5.6e-09 35.9 0.0 0.00022 20.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 001316264.1_06924001_1 - 2.2e-06 27.0 0.0 0.0017 17.5 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001316264.1_06924001_1 - 1.6e-05 25.3 0.0 0.065 13.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001316264.1_06924001_1 - 0.00022 19.9 0.1 0.027 13.0 0.5 2.3 2 0 0 2 2 2 1 HI0933-like protein MCRA PF06100.9 001316264.1_06924001_1 - 0.00059 18.6 0.0 0.27 9.8 0.0 2.1 2 0 0 2 2 2 2 MCRA family FAD_binding_2 PF00890.22 001316264.1_06924001_1 - 0.0012 17.9 0.7 0.0018 17.3 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.17 001316264.1_06924001_1 - 0.0013 17.9 0.1 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.5 001316264.1_06924001_1 - 0.0014 18.0 0.1 0.0021 17.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.15 001316264.1_06924001_1 - 0.0055 15.9 0.1 0.0099 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.12 001316264.1_06924001_1 - 0.0078 15.0 0.3 3 6.4 0.1 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.10 001316264.1_06924001_1 - 0.015 14.2 0.0 0.092 11.6 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.12 001316264.1_06924001_1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RNase_H2-Ydr279 PF09468.8 001316264.1_06924001_1 - 0.042 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GIDA PF01134.20 001316264.1_06924001_1 - 0.49 9.3 1.2 0.89 8.4 0.7 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Cellulose_synt PF03552.12 001316027.1_06927001_3 - 0 1324.8 0.0 0 1324.4 0.0 1.1 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001316027.1_06927001_3 - 3.6e-39 132.6 8.6 8.2e-39 131.5 8.6 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001316027.1_06927001_3 - 1.2e-08 34.9 0.1 1.2e-08 34.9 0.1 3.0 4 0 0 4 4 4 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001316027.1_06927001_3 - 5.4e-05 22.7 12.7 5.4e-05 22.7 12.7 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Glyco_tranf_2_3 PF13641.4 001316027.1_06927001_3 - 0.0011 18.8 0.1 0.027 14.2 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase like family 2 FYVE_2 PF02318.14 001316027.1_06927001_3 - 0.0012 18.9 3.1 0.0012 18.9 3.1 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger Prok-RING_1 PF14446.4 001316027.1_06927001_3 - 0.063 13.1 11.2 0.75 9.6 11.3 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Myb_DNA-binding PF00249.29 001316136.1_06923001_1 - 1.5e-31 108.1 2.4 4e-15 55.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316136.1_06923001_1 - 1.4e-18 66.7 1.6 2.6e-09 37.0 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SAGA-Tad1 PF12767.5 001316136.1_06923001_1 - 0.042 13.5 0.5 0.053 13.2 0.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Myb_DNA-bind_7 PF15963.3 001316136.1_06923001_1 - 0.061 13.1 0.0 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Myb DNA-binding like Pardaxin PF07425.9 001316136.1_06923001_2 - 0.4 10.2 1.8 0.88 9.1 1.8 1.5 1 0 0 1 1 1 0 Pardaxin Pkinase PF00069.23 001316234.1_06924001_1 - 1.4e-77 260.5 0.0 4.6e-77 258.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain EF-hand_1 PF00036.30 001316234.1_06924001_1 - 3.8e-29 97.9 3.2 7.1e-08 31.3 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001316234.1_06924001_1 - 3.3e-27 94.6 3.2 2.2e-15 56.7 2.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.15 001316234.1_06924001_1 - 2.5e-25 89.1 0.0 5.4e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.4 001316234.1_06924001_1 - 7.3e-21 72.2 3.8 8.4e-05 22.1 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001316234.1_06924001_1 - 5.2e-19 66.7 1.3 3.4e-05 23.0 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001316234.1_06924001_1 - 1.1e-16 60.2 4.3 1.6e-06 27.7 0.0 3.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.5 001316234.1_06924001_1 - 7.1e-07 29.0 1.7 0.018 14.8 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001316234.1_06924001_1 - 1.2e-06 28.7 0.3 7e-05 22.9 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain Kinase-like PF14531.4 001316234.1_06924001_1 - 3.5e-05 23.1 0.0 0.0049 16.1 0.0 3.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001316234.1_06924001_1 - 7e-05 22.1 0.5 0.00018 20.8 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.7 001316234.1_06924001_1 - 0.00022 21.4 1.3 0.0027 17.9 0.6 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001316234.1_06924001_1 - 0.0023 18.6 0.1 0.53 11.1 0.2 2.4 1 1 1 2 2 2 1 EF-hand domain DUF1198 PF06711.9 001316234.1_06924001_1 - 0.016 15.2 0.7 0.037 14.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) APH PF01636.21 001316234.1_06924001_1 - 0.054 13.3 0.0 0.34 10.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family P-II PF00543.20 001316234.1_06924001_1 - 0.61 10.6 2.5 69 4.0 0.1 3.5 3 1 1 4 4 3 0 Nitrogen regulatory protein P-II ExbD PF02472.14 001316234.1_06924001_1 - 0.71 9.9 3.6 22 5.1 0.1 2.8 2 1 1 3 3 2 0 Biopolymer transport protein ExbD/TolR DUF615 PF04751.12 001316234.1_06924001_1 - 0.72 9.7 5.1 5 6.9 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF615) DUF947 PF06102.10 001316234.1_06924001_1 - 1.6 8.5 5.8 0.3 10.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF947) SQS_PSY PF00494.17 001315972.1_06924001_1 - 9.3e-75 251.4 1.6 1.5e-74 250.7 1.6 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Pkinase PF00069.23 001315882.1_06924001_1 - 2.9e-75 252.9 0.0 4.4e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001315882.1_06924001_1 - 2.1e-30 101.8 11.1 3.1e-08 32.5 0.1 4.6 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001315882.1_06924001_1 - 9.5e-28 97.0 0.0 1.6e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.4 001315882.1_06924001_1 - 3.8e-27 91.8 4.3 1.4e-07 30.8 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.4 001315882.1_06924001_1 - 4.9e-25 87.7 8.5 4.4e-12 46.2 1.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.4 001315882.1_06924001_1 - 9.4e-23 78.5 9.5 2.3e-06 26.7 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001315882.1_06924001_1 - 1.3e-18 66.3 11.7 1e-06 28.2 0.1 4.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.5 001315882.1_06924001_1 - 5.1e-08 32.7 2.0 0.0028 17.4 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001315882.1_06924001_1 - 2.4e-07 30.9 0.3 0.0013 18.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.12 001315882.1_06924001_1 - 7.2e-05 22.1 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001315882.1_06924001_1 - 0.00011 21.5 0.0 0.00045 19.5 0.0 1.9 2 1 0 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.7 001315882.1_06924001_1 - 0.002 18.3 0.3 0.34 11.1 0.1 2.5 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.21 001315882.1_06924001_1 - 0.003 17.4 0.0 0.34 10.7 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family PMBR PF09373.8 001315882.1_06924001_1 - 0.074 13.1 0.3 1.2 9.2 0.0 3.2 4 0 0 4 4 4 0 Pseudomurein-binding repeat EF-hand_11 PF08976.9 001315882.1_06924001_1 - 0.082 13.7 0.1 17 6.2 0.0 2.6 2 1 1 3 3 2 0 EF-hand domain Cytokin-bind PF09265.8 001316280.1_06924001_1 - 1.1e-110 369.4 0.1 1.4e-110 369.0 0.1 1.1 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 001316280.1_06924001_1 - 2.4e-16 59.6 0.3 3.8e-16 59.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.23 001316216.1_06923001_1 - 4.3e-70 236.0 0.0 5.6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316216.1_06923001_1 - 3.5e-31 108.3 0.0 5.2e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001316216.1_06923001_1 - 1.2e-05 24.7 0.0 0.00015 21.0 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001316216.1_06923001_1 - 0.0013 18.0 0.1 0.0021 17.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CHASE PF03924.11 001315703.1_06927001_1 - 7.8e-38 130.2 0.0 1.5e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 CHASE domain HATPase_c PF02518.24 001315703.1_06927001_1 - 3.7e-31 107.8 0.2 1.2e-30 106.2 0.2 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.22 001315703.1_06927001_1 - 2.6e-23 82.2 0.0 2.3e-21 75.9 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.23 001315703.1_06927001_1 - 1e-17 63.8 0.0 2.3e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain SE PF08491.8 001315561.2_06924001_3 - 4.1e-115 383.4 0.1 5.4e-115 383.0 0.1 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.17 001315561.2_06924001_3 - 1.9e-16 60.2 0.0 3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.22 001315561.2_06924001_3 - 9.5e-12 45.1 0.1 1.3e-05 24.9 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.22 001315561.2_06924001_3 - 3.1e-07 29.7 0.2 7.1e-05 21.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.4 001315561.2_06924001_3 - 1.9e-06 27.9 0.4 4.4e-06 26.7 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.20 001315561.2_06924001_3 - 2.4e-05 23.4 0.9 0.00021 20.4 0.9 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.12 001315561.2_06924001_3 - 0.0002 20.6 0.2 0.00071 18.8 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.15 001315561.2_06924001_3 - 0.0009 18.4 0.0 0.0023 17.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.5 001315561.2_06924001_3 - 0.0034 16.7 0.6 0.0059 15.9 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.25 001315561.2_06924001_3 - 0.0035 17.8 0.7 0.0082 16.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.12 001315561.2_06924001_3 - 0.0037 16.0 0.1 0.17 10.6 0.0 2.4 2 1 0 3 3 3 1 Tryptophan halogenase ApbA PF02558.14 001315561.2_06924001_3 - 0.024 14.1 0.2 0.05 13.1 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.18 001315561.2_06924001_3 - 0.037 13.9 0.4 0.87 9.5 0.0 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.16 001315561.2_06924001_3 - 0.043 13.6 0.1 0.067 12.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.12 001315561.2_06924001_3 - 0.049 12.2 0.1 0.074 11.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF1188 PF06690.9 001315561.2_06924001_3 - 0.081 12.3 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Lycopene_cycl PF05834.10 001315561.2_06924001_3 - 0.16 10.8 0.1 0.31 9.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.16 001315561.2_06924001_3 - 0.16 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ubiquitin PF00240.21 001316148.1_06923001_2 - 3.4e-16 58.6 0.9 6.7e-16 57.6 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.9 001316148.1_06923001_2 - 1.1e-14 53.8 1.1 2e-14 52.9 1.1 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.6 001316148.1_06923001_2 - 2.8e-06 26.9 1.8 6e-06 25.9 1.8 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.29 001316148.1_06923001_2 - 1.5e-05 24.6 0.0 3.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_2 PF14560.4 001316148.1_06923001_2 - 0.0025 18.1 0.2 0.0075 16.6 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.7 001316148.1_06923001_2 - 0.028 14.8 0.1 0.091 13.2 0.1 1.9 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Peptidase_M16 PF00675.18 001316148.1_06923001_3 - 0.046 13.6 2.6 0.53 10.1 2.0 2.0 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) Pkinase_Tyr PF07714.15 001315639.1_06924001_1 - 6.5e-75 251.6 0.0 8.4e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001315639.1_06924001_1 - 8.6e-63 212.0 0.0 1.2e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ACT PF01842.23 001315639.1_06924001_1 - 1.9e-06 27.4 0.0 4.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 ACT domain Kinase-like PF14531.4 001315639.1_06924001_1 - 0.0031 16.8 0.0 0.0071 15.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001315639.1_06924001_1 - 0.0057 16.5 0.0 0.18 11.6 0.0 2.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family ACT_6 PF13740.4 001315639.1_06924001_1 - 0.0087 15.9 0.1 0.096 12.5 0.0 2.4 2 0 0 2 2 2 1 ACT domain p450 PF00067.20 001316270.1_06923001_1 - 1.3e-100 337.3 0.0 1.4e-100 337.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Goodbye PF17109.3 001316270.1_06923001_1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Transposase_31 PF04754.10 001316270.1_06923001_1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative transposase, YhgA-like P12 PF12669.5 001316270.1_06923001_1 - 0.61 10.4 2.9 0.37 11.1 0.3 1.8 2 0 0 2 2 2 0 Virus attachment protein p12 family AA_kinase PF00696.26 001315755.1_06926001_3 - 1.6e-39 135.8 0.1 2.8e-39 135.0 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.20 001315755.1_06926001_3 - 1.7e-07 30.0 0.2 1.5e-05 23.5 0.1 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Pex16 PF08610.8 001316107.1_06923001_1 - 8.1e-75 251.8 0.0 9.1e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Pkinase PF00069.23 001316284.1_06924001_1 - 1.6e-58 198.0 0.0 2.1e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316284.1_06924001_1 - 8.9e-35 120.1 0.0 1.2e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AMP-binding PF00501.26 001316278.1_06925001_2 - 7.2e-106 354.1 0.0 9.5e-106 353.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001316278.1_06925001_2 - 0.0025 18.6 0.7 0.008 17.0 0.7 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Chal_sti_synt_N PF00195.17 001316055.1_06923001_2 - 1.6e-119 397.2 0.0 3e-119 396.3 0.0 1.4 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.13 001316055.1_06923001_2 - 1.5e-71 239.1 0.0 2.3e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.8 001316055.1_06923001_2 - 1.4e-08 34.6 0.2 1.6e-06 28.1 0.0 3.2 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.10 001316055.1_06923001_2 - 2.8e-06 26.7 0.0 3.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.8 001316055.1_06923001_2 - 8.4e-06 25.4 0.1 2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III OpcA_G6PD_assem PF10128.7 001316055.1_06923001_2 - 0.033 13.5 0.0 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase subunit Pkinase PF00069.23 001316200.1_06923001_1 - 2e-69 233.8 0.0 2.6e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316200.1_06923001_1 - 9e-32 110.2 0.0 1.2e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_3_Rpc31 PF11705.6 001316200.1_06923001_1 - 0.00082 19.5 3.3 0.0014 18.7 3.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 APH PF01636.21 001316200.1_06923001_1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001316200.1_06923001_1 - 0.062 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.23 001315632.1_06924001_1 - 2.9e-77 259.5 0.0 7.7e-77 258.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain EF-hand_1 PF00036.30 001315632.1_06924001_1 - 7.9e-29 96.9 4.4 1.9e-07 30.0 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001315632.1_06924001_1 - 5.8e-27 93.8 2.8 1.8e-15 57.0 2.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.15 001315632.1_06924001_1 - 1.1e-25 90.3 0.0 1.9e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.4 001315632.1_06924001_1 - 2.8e-20 70.3 4.3 2.8e-05 23.6 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001315632.1_06924001_1 - 9.4e-20 69.1 2.3 1.4e-05 24.3 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001315632.1_06924001_1 - 8.7e-16 57.3 8.4 9e-09 34.8 0.4 4.2 2 1 3 5 5 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001315632.1_06924001_1 - 4e-06 27.0 0.8 0.00012 22.2 0.4 2.5 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.4 001315632.1_06924001_1 - 5.9e-06 25.7 0.0 9.7e-05 21.7 0.0 2.8 1 1 1 2 2 2 1 Kinase-like EF-hand_9 PF14658.4 001315632.1_06924001_1 - 6.4e-06 26.3 0.1 0.0034 17.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.5 001315632.1_06924001_1 - 9.5e-06 25.4 1.3 0.18 11.6 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.12 001315632.1_06924001_1 - 2.2e-05 23.8 0.1 5.1e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_11 PF08976.9 001315632.1_06924001_1 - 0.0087 16.8 0.1 5.5 7.8 0.0 2.5 1 1 1 2 2 2 1 EF-hand domain APH PF01636.21 001315632.1_06924001_1 - 0.045 13.5 0.0 0.45 10.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2321 PF10083.7 001315632.1_06924001_1 - 0.15 11.5 0.2 18 4.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) WRKY PF03106.13 001315925.1_06924001_1 - 4.2e-26 91.0 2.0 1e-25 89.7 2.0 1.7 1 0 0 1 1 1 1 WRKY DNA -binding domain IncA PF04156.12 001315925.1_06924001_1 - 0.02 14.5 2.5 0.042 13.5 2.5 1.5 1 0 0 1 1 1 0 IncA protein ICA69 PF04629.12 001315925.1_06924001_1 - 0.03 14.5 10.4 0.063 13.4 10.0 1.8 1 1 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain NAM PF02365.13 001315735.1_06922001_1 - 9.6e-28 96.7 0.0 3.4e-27 95.0 0.0 1.8 2 0 0 2 2 2 1 No apical meristem (NAM) protein BURP PF03181.13 001316082.1_06923001_3 - 1.2e-67 227.5 0.0 1.5e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 BURP domain Pollen_allerg_1 PF01357.19 001316111.1_06923001_1 - 9.3e-24 83.2 2.2 1.4e-23 82.6 2.2 1.3 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001316111.1_06923001_1 - 2.7e-21 75.5 0.0 6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase FabA PF07977.11 001315911.1_06922001_1 - 2e-34 118.0 0.2 3.4e-34 117.3 0.2 1.3 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.17 001315911.1_06922001_1 - 4.7e-06 26.0 0.1 7.7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.20 001315911.1_06922001_1 - 0.0087 16.3 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydrat_N PF13452.4 001315911.1_06922001_1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase EDR1 PF14381.4 001315727.1_06925001_1 - 6.7e-74 247.9 0.0 9.2e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Pkinase_Tyr PF07714.15 001315727.1_06925001_1 - 7.9e-73 244.8 0.0 1.2e-72 244.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001315727.1_06925001_1 - 5.5e-58 196.3 0.0 8.2e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ABC1 PF03109.14 001315727.1_06925001_1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family APH PF01636.21 001315727.1_06925001_1 - 0.026 14.3 0.0 0.08 12.7 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.4 001315727.1_06925001_1 - 0.061 12.5 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Na_H_Exchanger PF00999.19 001316157.1_06927001_1 - 9.8e-69 231.8 37.9 1.3e-68 231.4 37.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.27 001316157.1_06927001_1 - 9.8e-07 28.6 0.0 2.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ribosomal_S6e PF01092.17 001315981.1_06922001_1 - 1.2e-58 196.4 0.1 2.1e-58 195.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Pkinase PF00069.23 001316297.1_06929001_3 - 3.8e-73 246.0 0.0 7.3e-73 245.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316297.1_06929001_3 - 4e-51 173.7 0.0 7.3e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.21 001316297.1_06929001_3 - 0.00098 19.0 2.3 20 5.3 0.1 7.1 8 2 1 9 9 9 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.5 001316297.1_06929001_3 - 0.025 14.5 0.9 0.33 10.8 0.1 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 PTS_2-RNA PF01885.14 001316297.1_06929001_3 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family V-ATPase_H_C PF11698.6 001316297.1_06929001_3 - 0.076 13.0 0.2 0.56 10.2 0.0 2.6 2 0 0 2 2 2 0 V-ATPase subunit H Kinase-like PF14531.4 001316297.1_06929001_3 - 0.1 11.8 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.4 001316297.1_06929001_3 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 NAD_binding_5 PF07994.10 001315821.1_06924001_1 - 7.6e-144 478.9 0.0 9e-144 478.6 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.15 001315821.1_06924001_1 - 1.2e-46 157.3 1.4 1.9e-46 156.7 0.1 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase NAM PF02365.13 001316092.1_06923001_1 - 9.8e-27 93.5 0.1 1.7e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein FMN_dh PF01070.16 001316235.1_06923001_1 - 9.3e-138 458.9 0.3 1.1e-137 458.7 0.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.23 001316235.1_06923001_1 - 2.8e-06 26.5 0.8 2.8e-06 26.5 0.8 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.13 001316235.1_06923001_1 - 5.7e-06 25.8 0.2 9.9e-06 25.0 0.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.19 001316235.1_06923001_1 - 0.00011 21.4 0.4 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Glu_synthase PF01645.15 001316235.1_06923001_1 - 0.00049 19.2 0.2 0.00073 18.7 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.12 001316235.1_06923001_1 - 0.00078 18.7 0.8 0.041 13.1 0.0 2.5 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.10 001316235.1_06923001_1 - 0.00082 18.5 0.0 0.5 9.4 0.0 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF561) His_biosynth PF00977.19 001316235.1_06923001_1 - 0.0021 17.5 0.5 0.011 15.1 0.0 2.2 2 1 1 3 3 3 1 Histidine biosynthesis protein PA PF02225.20 001316235.1_06923001_1 - 0.0033 17.4 0.8 0.18 11.8 0.0 3.0 2 1 1 3 3 3 1 PA domain TMP-TENI PF02581.15 001316235.1_06923001_1 - 0.12 11.6 0.3 2.8 7.1 0.1 2.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI MIP PF00230.18 001316220.1_06922001_1 - 6.6e-85 284.3 12.0 7.5e-85 284.1 12.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Amino_oxidase PF01593.22 001315737.1_06924001_1 - 3.1e-80 270.6 0.0 3.6e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001315737.1_06924001_1 - 3.6e-15 55.8 0.1 7.4e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001315737.1_06924001_1 - 5.3e-09 36.0 0.0 0.00023 20.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 001315737.1_06924001_1 - 8.5e-07 28.4 0.0 0.00062 19.0 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001315737.1_06924001_1 - 1.4e-05 25.4 0.0 0.052 14.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001315737.1_06924001_1 - 0.00016 20.3 0.1 0.026 13.1 0.7 2.4 3 0 0 3 3 3 1 HI0933-like protein MCRA PF06100.9 001315737.1_06924001_1 - 0.00069 18.4 0.0 0.32 9.6 0.0 2.1 2 0 0 2 2 2 2 MCRA family FAD_binding_2 PF00890.22 001315737.1_06924001_1 - 0.00069 18.7 0.7 0.0011 18.0 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.5 001315737.1_06924001_1 - 0.001 18.4 0.1 0.0016 17.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.15 001315737.1_06924001_1 - 0.0023 17.1 0.1 0.004 16.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.17 001315737.1_06924001_1 - 0.0025 17.0 0.1 0.0042 16.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.12 001315737.1_06924001_1 - 0.0089 14.8 0.2 3.6 6.2 0.1 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.10 001315737.1_06924001_1 - 0.012 14.6 0.0 0.069 12.1 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.12 001315737.1_06924001_1 - 0.02 14.3 0.0 0.067 12.6 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RNase_H2-Ydr279 PF09468.8 001315737.1_06924001_1 - 0.063 12.7 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GIDA PF01134.20 001315737.1_06924001_1 - 0.35 9.8 1.2 0.66 8.9 0.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAM PF02365.13 001315987.1_06923001_1 - 8.4e-28 96.9 0.2 1.8e-27 95.9 0.2 1.6 1 0 0 1 1 1 1 No apical meristem (NAM) protein B3 PF02362.19 001315761.1_06925001_1 - 3.1e-16 59.0 0.0 7.5e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 B3 DNA binding domain Alginate_lyase PF05426.10 001315761.1_06925001_1 - 0.009 15.5 3.2 0.75 9.2 0.1 2.5 1 1 0 2 2 2 2 Alginate lyase Actin PF00022.17 001316010.1_06923001_1 - 1.5e-146 488.0 0.0 4.7e-146 486.4 0.0 1.6 1 1 0 1 1 1 1 Actin adh_short PF00106.23 001316039.1_06922001_1 - 1.8e-40 138.3 0.2 2.3e-40 138.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001316039.1_06922001_1 - 8.3e-24 84.3 0.1 1.1e-23 83.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001316039.1_06922001_1 - 1.2e-06 28.4 0.0 1.6e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.13 001316039.1_06922001_1 - 0.0018 17.3 0.1 0.0026 16.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.4 001316039.1_06922001_1 - 0.024 14.4 0.1 0.045 13.5 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding CHASE PF03924.11 001315963.1_06927001_1 - 3.9e-38 131.2 0.1 8.3e-38 130.1 0.1 1.6 1 0 0 1 1 1 1 CHASE domain HATPase_c PF02518.24 001315963.1_06927001_1 - 1.2e-32 112.7 0.2 2.7e-32 111.5 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.22 001315963.1_06927001_1 - 1.2e-22 80.1 0.3 7.6e-21 74.2 0.0 3.0 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.23 001315963.1_06927001_1 - 1.1e-15 57.3 0.0 2.3e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain IncA PF04156.12 001315963.1_06927001_1 - 0.035 13.8 1.3 6 6.5 0.2 2.6 2 0 0 2 2 2 0 IncA protein Lycopene_cycl PF05834.10 001315677.1_06924001_3 - 1.4e-155 517.9 0.0 1.6e-155 517.7 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.12 001315677.1_06924001_3 - 7.5e-05 22.0 0.1 0.00047 19.4 0.1 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001315677.1_06924001_3 - 0.00072 18.2 0.5 0.036 12.6 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.20 001315677.1_06924001_3 - 0.0036 16.3 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.22 001315677.1_06924001_3 - 0.01 15.3 0.0 2.5 7.5 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.22 001315677.1_06924001_3 - 0.013 14.4 1.2 0.023 13.7 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.15 001315677.1_06924001_3 - 0.08 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.5 001315677.1_06924001_3 - 0.1 11.8 0.5 0.15 11.2 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.4 001315677.1_06924001_3 - 0.28 10.2 1.5 0.44 9.6 1.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.23 001316143.1_06924001_1 - 7.1e-69 232.0 0.0 9.5e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316143.1_06924001_1 - 2.3e-30 105.6 0.0 3.2e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.30 001316143.1_06924001_1 - 7.3e-26 87.6 3.0 9.5e-06 24.7 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001316143.1_06924001_1 - 1.6e-23 80.9 5.6 1.6e-05 24.1 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001316143.1_06924001_1 - 5.3e-20 69.5 7.2 3.1e-05 23.4 0.1 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.4 001316143.1_06924001_1 - 9.8e-20 70.7 3.3 9.7e-09 35.4 0.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.4 001316143.1_06924001_1 - 3.1e-16 58.8 0.3 2.1e-06 27.2 0.0 3.9 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001316143.1_06924001_1 - 7.9e-08 32.5 0.2 0.0011 19.2 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.4 001316143.1_06924001_1 - 1.9e-05 24.0 0.0 2.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001316143.1_06924001_1 - 0.00095 19.0 0.0 0.79 9.5 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.12 001316143.1_06924001_1 - 0.0014 17.9 0.0 0.0037 16.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.5 001316143.1_06924001_1 - 0.0046 16.7 3.7 0.21 11.4 0.5 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.23 001315883.1_06924001_1 - 7.8e-72 241.7 0.0 1.3e-71 240.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001315883.1_06924001_1 - 5.7e-33 109.9 10.4 8.1e-08 31.1 1.4 4.9 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.4 001315883.1_06924001_1 - 4.9e-27 91.4 3.6 4.4e-07 29.2 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001315883.1_06924001_1 - 3.5e-26 91.3 3.5 2.3e-12 47.0 0.9 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001315883.1_06924001_1 - 2e-25 87.0 5.0 4e-06 26.0 0.0 4.6 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001315883.1_06924001_1 - 5.4e-25 88.0 0.0 1.2e-24 86.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_8 PF13833.4 001315883.1_06924001_1 - 1.6e-21 75.7 12.7 2.2e-07 30.4 0.1 5.8 3 1 3 6 6 6 4 EF-hand domain pair EF-hand_4 PF12763.5 001315883.1_06924001_1 - 2.1e-07 30.7 1.0 0.00041 20.1 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001315883.1_06924001_1 - 3.1e-07 30.5 0.8 0.0011 19.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.12 001315883.1_06924001_1 - 6.7e-06 25.5 0.1 1.4e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA_synt_1c_R1 PF04558.13 001315883.1_06924001_1 - 0.00023 21.0 0.1 0.00057 19.8 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 SPARC_Ca_bdg PF10591.7 001315883.1_06924001_1 - 0.00038 20.6 0.4 1.1 9.5 0.2 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.21 001315883.1_06924001_1 - 0.0033 17.2 0.1 2.8 7.7 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family EF-hand_11 PF08976.9 001315883.1_06924001_1 - 0.0048 17.6 0.0 2.7 8.8 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain DUF374 PF04028.11 001315883.1_06924001_1 - 0.028 13.9 0.0 0.082 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Herpes_UL36 PF03586.11 001315883.1_06924001_1 - 0.11 11.6 0.4 2 7.5 0.1 2.2 1 1 1 2 2 2 0 Herpesvirus UL36 tegument protein Kinase-like PF14531.4 001315883.1_06924001_1 - 0.12 11.5 0.2 1.2 8.2 0.1 2.5 1 1 0 2 2 2 0 Kinase-like DUF4513 PF14983.4 001315883.1_06924001_1 - 0.15 12.0 0.3 3.7 7.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4513) NAM PF02365.13 001315936.1_06923001_1 - 4.7e-28 97.7 0.1 8.9e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein WRKY PF03106.13 001316268.1_06922001_2 - 1.5e-26 92.4 0.2 1.5e-26 92.4 0.2 1.8 2 0 0 2 2 2 1 WRKY DNA -binding domain Plant_zn_clust PF10533.7 001316268.1_06922001_2 - 3.9e-16 58.6 9.5 8.1e-16 57.6 9.5 1.6 1 0 0 1 1 1 1 Plant zinc cluster domain Pkinase PF00069.23 001316126.1_06923001_1 - 1.6e-71 240.7 0.0 1.9e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316126.1_06923001_1 - 2e-38 132.1 0.0 2.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001316126.1_06923001_1 - 4.2e-06 26.1 0.0 0.00038 19.7 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.21 001316126.1_06923001_1 - 0.00055 19.8 0.0 0.027 14.3 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.20 001316126.1_06923001_1 - 0.0046 16.4 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.9 001316126.1_06923001_1 - 0.0059 15.6 0.0 0.013 14.5 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 Choline_kinase PF01633.18 001316126.1_06923001_1 - 0.0094 15.4 0.0 0.017 14.6 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.12 001316126.1_06923001_1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HCO3_cotransp PF00955.19 001315600.1_06925001_1 - 5.4e-84 282.8 3.7 3.5e-36 125.0 1.9 3.1 2 1 1 3 3 3 3 HCO3- transporter family Pec_lyase_C PF00544.17 001316164.1_06924001_2 - 3.7e-22 78.8 2.5 1.5e-21 76.9 2.5 1.8 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.4 001316164.1_06924001_2 - 5.2e-06 26.3 3.1 1.3e-05 25.0 2.8 1.8 1 1 0 1 1 1 1 Right handed beta helix region Bac_export_2 PF01312.17 001316164.1_06924001_2 - 0.21 10.7 0.1 0.3 10.1 0.1 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Myb_DNA-binding PF00249.29 001316181.1_06922001_2 - 7.5e-31 105.9 1.9 2e-14 53.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316181.1_06922001_2 - 1.4e-17 63.5 0.9 4.1e-10 39.6 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.6 001316181.1_06922001_2 - 0.014 15.3 0.7 0.028 14.4 0.7 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.3 001316181.1_06922001_2 - 0.053 13.3 0.5 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Myb DNA-binding like IRF PF00605.15 001316181.1_06922001_2 - 0.12 12.5 5.1 2 8.6 5.1 2.1 1 1 0 1 1 1 0 Interferon regulatory factor transcription factor Myb_DNA-binding PF00249.29 001316273.1_06923001_1 - 5.4e-33 112.8 4.4 2e-17 62.9 0.8 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316273.1_06923001_1 - 4.6e-23 81.1 1.2 3.8e-13 49.3 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001316273.1_06923001_1 - 0.0008 19.3 0.5 0.1 12.5 0.0 3.0 2 2 1 3 3 3 1 SLIDE AAA_22 PF13401.4 001316273.1_06923001_1 - 0.06 13.5 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain WRKY PF03106.13 001316305.1_06922001_1 - 8.9e-27 93.1 4.7 2e-26 92.0 4.7 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain DNase-RNase PF02577.12 001316305.1_06922001_1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Bifunctional nuclease p450 PF00067.20 001315954.1_06924001_3 - 1.2e-107 360.4 0.0 1.5e-107 360.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mg_chelatase PF01078.19 001316128.1_06923001_1 - 2.4e-11 43.3 0.1 2.2e-07 30.4 0.0 2.6 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.21 001316128.1_06923001_1 - 1.1e-08 34.4 0.6 5.6e-06 25.5 0.2 3.2 2 1 0 2 2 2 2 MCM2/3/5 family AAA_5 PF07728.12 001316128.1_06923001_1 - 1.3e-06 28.3 0.0 0.005 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.4 001316128.1_06923001_1 - 0.00014 22.1 0.0 0.00044 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.4 001316128.1_06923001_1 - 0.00021 21.6 0.2 0.0012 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.24 001316128.1_06923001_1 - 0.00037 20.1 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.27 001316128.1_06923001_1 - 0.0046 17.2 0.0 0.038 14.3 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.25 001316128.1_06923001_1 - 0.006 17.0 0.0 0.81 10.1 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.4 001316128.1_06923001_1 - 0.014 15.0 0.1 0.036 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.11 001316128.1_06923001_1 - 0.014 14.4 0.0 0.033 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.4 001316128.1_06923001_1 - 0.034 14.5 0.1 0.32 11.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_32 PF13654.4 001316128.1_06923001_1 - 0.072 11.7 0.6 12 4.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.4 001316128.1_06923001_1 - 0.073 12.7 0.0 0.3 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain LRR_8 PF13855.4 001315968.1_06922001_1 - 4.3e-13 48.7 13.2 1e-05 25.1 0.6 4.8 1 1 3 5 5 5 4 Leucine rich repeat LRRNT_2 PF08263.10 001315968.1_06922001_1 - 1.5e-10 41.0 2.8 1.5e-10 41.0 2.8 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001315968.1_06922001_1 - 2.4e-09 37.1 18.4 1e-05 25.6 3.6 5.7 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001315968.1_06922001_1 - 1.9e-07 30.4 18.4 0.11 12.9 0.1 7.8 7 1 1 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.4 001315968.1_06922001_1 - 5.1e-05 22.9 17.9 0.92 9.6 0.2 7.6 9 0 0 9 9 9 4 Leucine Rich repeat Caleosin PF05042.11 001316096.1_06922001_2 - 4.3e-74 247.9 0.0 5.5e-74 247.6 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein Amidohydro_1 PF01979.18 001315618.1_06923001_1 - 9e-30 104.0 0.0 1.1e-29 103.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family DUF3161 PF11362.6 001315618.1_06923001_1 - 0.15 11.9 0.0 26 4.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) Actin PF00022.17 001316079.1_06923001_1 - 5.4e-148 492.8 0.0 2e-147 491.0 0.0 1.7 1 1 0 1 1 1 1 Actin KNOX2 PF03791.11 001315986.1_06923001_3 - 1.9e-19 68.9 0.3 4.2e-19 67.8 0.3 1.6 1 0 0 1 1 1 1 KNOX2 domain Homeobox_KN PF05920.9 001315986.1_06923001_3 - 2.1e-18 65.8 2.6 4.8e-18 64.7 2.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain KNOX1 PF03790.11 001315986.1_06923001_3 - 4.9e-16 58.1 1.2 9.4e-16 57.2 1.2 1.5 1 0 0 1 1 1 1 KNOX1 domain Homeobox PF00046.27 001315986.1_06923001_3 - 2.4e-05 23.9 0.8 7.7e-05 22.3 0.8 1.9 1 0 0 1 1 1 1 Homeobox domain ELK PF03789.11 001315986.1_06923001_3 - 0.0051 16.7 0.4 0.0051 16.7 0.4 2.6 3 0 0 3 3 3 1 ELK domain NAM PF02365.13 001316138.1_06924001_3 - 9.2e-26 90.4 0.1 1.5e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein WRKY PF03106.13 001315944.1_06923001_3 - 2.3e-26 91.7 0.1 2.3e-26 91.7 0.1 2.3 2 0 0 2 2 2 1 WRKY DNA -binding domain Plant_zn_clust PF10533.7 001315944.1_06923001_3 - 1.1e-15 57.2 9.4 3.6e-15 55.5 9.4 1.9 1 0 0 1 1 1 1 Plant zinc cluster domain Pkinase PF00069.23 001316089.1_06923001_1 - 1.6e-67 227.6 0.0 1.8e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316089.1_06923001_1 - 5.9e-37 127.2 0.0 7.3e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001316089.1_06923001_1 - 6.9e-06 26.0 0.0 0.0045 16.8 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.20 001316089.1_06923001_1 - 0.00028 20.4 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.4 001316089.1_06923001_1 - 0.00047 19.4 0.0 0.0044 16.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.9 001316089.1_06923001_1 - 0.086 11.8 0.1 0.23 10.3 0.0 1.7 2 1 0 2 2 2 0 Seadornavirus VP7 WRKY PF03106.13 001316238.1_06923001_2 - 5.8e-51 170.6 11.6 2.5e-26 91.7 3.0 2.6 2 0 0 2 2 2 2 WRKY DNA -binding domain CG-1 PF03859.14 001316238.1_06923001_2 - 0.0017 18.0 0.2 0.79 9.4 0.1 2.8 3 0 0 3 3 3 2 CG-1 domain WRKY PF03106.13 001315793.1_06922001_1 - 3.8e-26 91.1 3.7 6.2e-26 90.4 3.7 1.4 1 0 0 1 1 1 1 WRKY DNA -binding domain DUF4589 PF15252.4 001315793.1_06922001_1 - 6.2e-05 23.0 1.5 6.2e-05 23.0 1.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4589) NPR1_like_C PF12313.6 001316011.1_06925001_2 - 2.4e-74 249.2 3.2 4.3e-74 248.3 3.2 1.4 1 0 0 1 1 1 1 NPR1/NIM1 like defence protein C terminal BTB PF00651.29 001316011.1_06925001_2 - 2.2e-10 40.6 0.3 9e-10 38.6 0.3 2.1 1 1 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.4 001316011.1_06925001_2 - 1.7e-07 31.5 1.1 4.9e-05 23.7 0.1 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001316011.1_06925001_2 - 1.2e-06 28.8 2.1 8.1e-05 23.0 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001316011.1_06925001_2 - 1.3e-05 25.3 0.1 0.078 13.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF3420 PF11900.6 001316011.1_06925001_2 - 1.7e-05 24.7 0.4 3.5e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3420) Ank_3 PF13606.4 001316011.1_06925001_2 - 1.7e-05 24.7 2.9 0.52 10.9 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.4 001316011.1_06925001_2 - 0.00073 19.7 4.0 0.0012 19.0 0.1 3.0 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Glyco_hydro_32N PF00251.18 001315602.1_06924001_2 - 6.3e-107 357.5 5.9 8.7e-107 357.1 5.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.10 001315602.1_06924001_2 - 6.2e-14 52.4 0.0 1.3e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PP2C PF00481.19 001316021.1_06923001_1 - 8.8e-73 245.0 0.0 1.4e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001316021.1_06923001_1 - 0.00014 21.5 0.0 0.00028 20.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.10 001316021.1_06923001_1 - 0.004 16.9 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PCNA_C PF02747.13 001316112.1_06923001_3 - 1.6e-60 202.7 0.1 2.8e-60 201.9 0.1 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.16 001316112.1_06923001_3 - 1.6e-59 199.0 2.3 3.6e-59 197.9 2.4 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.11 001316112.1_06923001_3 - 1.1e-06 28.1 0.1 1.5e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 End_beta_propel PF12217.6 001316112.1_06923001_3 - 0.14 10.7 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase Pkinase PF00069.23 001316000.1_06924001_1 - 1.1e-74 251.0 0.0 1.5e-73 247.3 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain EF-hand_1 PF00036.30 001316000.1_06924001_1 - 1.4e-32 108.6 5.9 2.9e-09 35.7 0.3 4.6 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001316000.1_06924001_1 - 2.3e-27 95.8 0.0 4.5e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001316000.1_06924001_1 - 1.9e-26 92.2 5.5 2.5e-14 53.3 1.8 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001316000.1_06924001_1 - 5.5e-25 85.0 3.1 2.2e-07 30.1 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.4 001316000.1_06924001_1 - 3.9e-24 82.9 3.1 0.00016 20.9 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001316000.1_06924001_1 - 2.7e-21 75.0 12.0 2.8e-10 39.7 0.8 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.5 001316000.1_06924001_1 - 2.1e-08 33.9 1.2 0.0049 16.7 0.3 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001316000.1_06924001_1 - 5.3e-08 33.0 1.7 0.0052 17.0 0.0 2.8 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.4 001316000.1_06924001_1 - 2.4e-07 30.8 0.2 0.012 15.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.8 001316000.1_06924001_1 - 8.1e-06 25.7 0.4 0.13 12.3 0.0 3.4 3 0 0 3 3 3 2 Ca2+ insensitive EF hand Kinase-like PF14531.4 001316000.1_06924001_1 - 9e-05 21.8 0.0 0.0096 15.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.12 001316000.1_06924001_1 - 0.0011 18.2 0.8 0.0016 17.7 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Toprim_2 PF13155.4 001316000.1_06924001_1 - 0.002 18.5 0.9 3.4 8.1 0.3 3.2 1 1 0 2 2 2 1 Toprim-like Caleosin PF05042.11 001316000.1_06924001_1 - 0.0098 15.7 0.2 0.077 12.8 0.2 2.7 2 1 0 2 2 2 1 Caleosin related protein Gp-FAR-1 PF05823.10 001316000.1_06924001_1 - 0.013 15.7 3.2 0.53 10.5 0.2 2.5 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) APH PF01636.21 001316000.1_06924001_1 - 0.027 14.3 0.1 3.3 7.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3800 PF12686.5 001316000.1_06924001_1 - 0.057 13.0 2.5 0.72 9.3 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3800) Aa_trans PF01490.16 001315567.1_06924001_3 - 1.4e-123 412.5 27.0 1.4e-123 412.5 27.0 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein SRF-TF PF00319.16 001316207.1_06922001_1 - 2e-26 91.1 0.2 3.2e-26 90.4 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001316207.1_06922001_1 - 7e-26 90.1 9.1 1.7e-25 88.8 9.1 1.6 1 0 0 1 1 1 1 K-box region AKAP2_C PF15304.4 001316207.1_06922001_1 - 0.0091 15.2 4.1 0.012 14.7 4.1 1.1 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus DUF2721 PF11026.6 001316207.1_06922001_1 - 1.9 8.2 3.5 3.8 7.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Acyltransf_C PF16076.3 001316052.1_06923001_3 - 1.5e-22 79.4 0.0 3.5e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.19 001316052.1_06923001_3 - 2.8e-17 62.5 0.0 5.9e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Porin_3 PF01459.20 001315594.1_06922001_1 - 8e-61 205.7 3.6 8.9e-61 205.6 3.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin WRKY PF03106.13 001315903.1_06923001_1 - 2e-26 92.0 1.1 3.5e-26 91.2 0.4 1.8 2 0 0 2 2 2 1 WRKY DNA -binding domain FLYWCH PF04500.14 001315903.1_06923001_1 - 0.04 13.9 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain Mrx7 PF10906.6 001315903.1_06923001_2 - 0.04 14.0 0.1 0.087 12.9 0.1 1.5 1 0 0 1 1 1 0 MIOREX complex component 7 GSHPx PF00255.17 001315857.1_06922001_3 - 8.7e-41 137.7 0.0 1.3e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 001315857.1_06922001_3 - 1e-08 35.0 0.1 4e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.8 001315857.1_06922001_3 - 2.9e-06 26.9 0.1 1.3e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 Redoxin NAM PF02365.13 001316242.1_06923001_1 - 5.4e-25 87.9 0.3 1.3e-24 86.7 0.2 1.6 2 0 0 2 2 2 1 No apical meristem (NAM) protein 2OG-FeII_Oxy PF03171.18 001316172.1_06923001_1 - 4.2e-29 100.9 0.0 7.1e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001316172.1_06923001_1 - 2.2e-16 60.5 0.0 3.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WW PF00397.24 001316172.1_06923001_2 - 0.24 11.2 0.8 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 WW domain Glyco_hydro_1 PF00232.16 001316219.1_06924001_1 - 6.3e-144 479.6 1.3 8.1e-144 479.3 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AMP-binding PF00501.26 001315619.1_06925001_1 - 1.7e-101 339.7 0.0 2.2e-101 339.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001315619.1_06925001_1 - 0.007 17.2 0.0 0.02 15.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aa_trans PF01490.16 001316193.1_06924001_2 - 1.5e-120 402.6 21.9 1.7e-120 402.3 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3040 PF11239.6 001316193.1_06924001_2 - 7.7 6.7 10.1 9.4 6.5 0.9 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Cu-oxidase PF00394.20 001316078.1_06924001_3 - 1.1e-41 142.5 0.3 4.9e-41 140.4 0.0 2.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.13 001316078.1_06924001_3 - 6.7e-39 132.5 1.4 6.7e-39 132.5 1.4 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.12 001316078.1_06924001_3 - 5.7e-26 90.7 0.3 3.1e-25 88.4 0.0 2.3 3 0 0 3 3 3 1 Multicopper oxidase Iso_dh PF00180.18 001315823.1_06923001_3 - 6.5e-83 278.6 0.1 7.8e-83 278.4 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AIG1 PF04548.14 001315988.1_06922001_1 - 5.2e-34 117.3 0.2 1.5e-33 115.8 0.2 1.7 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.21 001315988.1_06922001_1 - 2.5e-12 46.7 0.1 5.3e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001315988.1_06922001_1 - 1.4e-07 31.4 0.2 4.2e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.21 001315988.1_06922001_1 - 2.1e-05 24.5 2.7 0.043 13.7 0.8 2.4 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.16 001315988.1_06922001_1 - 0.00087 18.7 0.2 0.0015 17.9 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.16 001315988.1_06922001_1 - 0.0024 17.0 0.3 0.0088 15.2 0.3 1.9 1 1 0 1 1 1 1 Septin IIGP PF05049.11 001315988.1_06922001_1 - 0.061 12.2 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.4 001315988.1_06922001_1 - 0.067 13.4 0.7 0.18 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.16 001315988.1_06922001_1 - 0.075 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.25 001315988.1_06922001_1 - 0.13 12.7 0.1 0.68 10.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Pectinesterase PF01095.17 001315863.1_06924001_2 - 9.6e-135 447.9 3.8 1.4e-134 447.3 3.8 1.2 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.13 001315863.1_06924001_2 - 2.8e-17 63.3 0.1 4.3e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Auxin_resp PF06507.11 001316068.1_06926001_1 - 8.1e-37 125.2 0.3 1.8e-36 124.1 0.3 1.6 1 0 0 1 1 1 1 Auxin response factor B3 PF02362.19 001316068.1_06926001_1 - 5.1e-21 74.3 0.0 3e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 B3 DNA binding domain AUX_IAA PF02309.14 001316068.1_06926001_1 - 5.2e-13 49.3 3.0 7.2e-06 25.9 1.0 2.4 1 1 1 2 2 2 2 AUX/IAA family DUF3675 PF12428.6 001315648.1_06922001_1 - 8.6e-40 135.9 0.0 2.1e-39 134.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3675) RINGv PF12906.5 001315648.1_06922001_1 - 2.3e-12 46.7 13.6 3.7e-12 46.0 13.6 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.4 001315648.1_06922001_1 - 0.016 15.3 10.0 0.1 12.7 10.7 2.0 1 1 1 2 2 2 0 Ring finger domain DUF2024 PF09630.8 001315648.1_06922001_1 - 0.75 9.6 3.1 0.38 10.5 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) WRKY PF03106.13 001316266.1_06923001_1 - 5.3e-53 177.1 15.5 2e-26 92.0 2.6 2.4 2 0 0 2 2 2 2 WRKY DNA -binding domain FLYWCH PF04500.14 001316266.1_06923001_1 - 0.094 12.7 1.2 5.5 7.1 0.2 2.4 2 0 0 2 2 2 0 FLYWCH zinc finger domain FAR1 PF03101.13 001316266.1_06923001_1 - 0.22 12.1 2.0 3 8.5 0.0 2.8 2 1 1 3 3 3 0 FAR1 DNA-binding domain Ogr_Delta PF04606.10 001316266.1_06923001_1 - 0.69 9.8 3.0 17 5.3 0.0 2.9 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger NAM PF02365.13 001316302.1_06923001_1 - 2.5e-25 89.0 0.2 4.6e-25 88.2 0.2 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein Pkinase PF00069.23 001316137.1_06924001_1 - 8.2e-68 228.5 0.0 1.3e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316137.1_06924001_1 - 1.2e-31 109.9 0.0 1.8e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.30 001316137.1_06924001_1 - 3.9e-24 82.2 2.7 1.8e-05 23.8 0.0 4.8 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001316137.1_06924001_1 - 6.6e-24 82.2 4.6 2e-06 26.9 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001316137.1_06924001_1 - 2.2e-19 67.6 2.3 4e-05 23.1 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001316137.1_06924001_1 - 1.2e-18 67.2 3.2 1.3e-08 35.0 0.3 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001316137.1_06924001_1 - 5.2e-12 45.2 5.9 3.4e-06 26.6 0.0 4.2 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001316137.1_06924001_1 - 2.2e-07 31.0 0.6 0.00037 20.6 0.0 2.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.4 001316137.1_06924001_1 - 6.5e-07 28.8 0.0 1.7e-05 24.2 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001316137.1_06924001_1 - 0.0005 19.4 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001316137.1_06924001_1 - 0.0068 16.2 0.0 1.2 8.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family EF-hand_4 PF12763.5 001316137.1_06924001_1 - 0.015 15.1 6.3 1.4 8.7 2.6 3.6 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand PTS_EIIB PF00367.18 001316137.1_06924001_1 - 0.092 12.1 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB KNOX2 PF03791.11 001316059.1_06923001_1 - 5.5e-21 73.9 1.0 1.8e-20 72.2 1.0 1.9 1 0 0 1 1 1 1 KNOX2 domain KNOX1 PF03790.11 001316059.1_06923001_1 - 1.7e-19 69.2 0.2 1.7e-19 69.2 0.2 1.9 2 0 0 2 2 2 1 KNOX1 domain Homeobox_KN PF05920.9 001316059.1_06923001_1 - 1.3e-17 63.2 4.2 3.4e-17 61.9 3.5 2.1 2 0 0 2 2 2 1 Homeobox KN domain ELK PF03789.11 001316059.1_06923001_1 - 3.3e-11 42.8 3.8 6.4e-11 41.9 3.8 1.5 1 0 0 1 1 1 1 ELK domain Homeobox PF00046.27 001316059.1_06923001_1 - 2e-07 30.6 1.8 3.7e-07 29.7 1.0 1.7 1 1 1 2 2 2 1 Homeobox domain WBP-1 PF11669.6 001316059.1_06923001_1 - 0.012 16.1 0.8 0.026 15.0 0.8 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 NAM PF02365.13 001316090.1_06923001_1 - 3.5e-30 104.6 0.8 6.1e-30 103.8 0.8 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein ELFV_dehydrog PF00208.19 001316212.1_06923001_2 - 5.4e-76 255.4 0.2 6.9e-76 255.0 0.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.16 001316212.1_06923001_2 - 6.1e-49 165.1 0.0 9.1e-49 164.5 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.17 001316212.1_06923001_2 - 0.027 13.7 0.1 0.056 12.7 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.19 001316212.1_06923001_2 - 0.16 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Cellulose_synt PF03552.12 001316177.1_06927001_2 - 0 1381.3 0.0 0 1381.3 0.0 1.3 2 0 0 2 2 2 1 Cellulose synthase zf-UDP PF14569.4 001316177.1_06927001_2 - 1.3e-37 127.6 7.1 2.4e-37 126.8 7.1 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001316177.1_06927001_2 - 3.4e-08 33.5 0.3 3.4e-08 33.5 0.3 3.1 4 0 0 4 4 3 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001316177.1_06927001_2 - 2.6e-05 23.7 11.7 5.3e-05 22.7 11.7 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Glycos_transf_2 PF00535.24 001316177.1_06927001_2 - 0.00017 21.3 0.1 0.00046 19.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Baculo_IE-1 PF05290.9 001316177.1_06927001_2 - 0.0027 17.5 4.5 0.0058 16.4 4.5 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Glyco_tranf_2_3 PF13641.4 001316177.1_06927001_2 - 0.0066 16.2 0.0 0.62 9.8 0.0 3.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 FYVE_2 PF02318.14 001316177.1_06927001_2 - 0.013 15.6 2.0 0.028 14.5 2.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.4 001316177.1_06927001_2 - 0.038 13.7 8.0 0.076 12.7 8.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.4 001316177.1_06927001_2 - 0.07 12.9 14.5 0.42 10.5 13.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.23 001316177.1_06927001_2 - 0.091 12.5 8.1 0.21 11.3 8.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.27 001316177.1_06927001_2 - 0.18 11.6 9.6 0.34 10.7 9.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.4 001316177.1_06927001_2 - 7.3 6.4 8.3 21 4.9 8.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AMP-binding PF00501.26 001315910.1_06925001_2 - 1.6e-104 349.7 0.0 2e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001315910.1_06925001_2 - 0.00022 22.0 0.0 0.00066 20.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OAD_gamma PF04277.11 001315910.1_06925001_2 - 0.34 11.4 2.8 0.74 10.3 2.8 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain NAM PF02365.13 001315653.1_06922001_1 - 3.2e-30 104.7 0.3 4.9e-30 104.1 0.3 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein zf-CCCH PF00642.22 001315653.1_06922001_1 - 0.34 10.8 1.7 3.6 7.5 0.0 2.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Steroid_dh PF02544.14 001315967.1_06923001_2 - 4.9e-26 91.4 1.3 4.9e-26 91.4 1.3 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PRIMA1 PF16101.3 001315967.1_06923001_2 - 9.5 6.2 6.0 13 5.8 4.3 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pkinase_Tyr PF07714.15 001316244.1_06923001_1 - 1.1e-55 188.6 0.0 1.5e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001316244.1_06923001_1 - 3.1e-52 177.4 0.0 4.9e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.5 001316244.1_06923001_1 - 1.5e-13 51.0 0.0 1e-12 48.3 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.28 001316244.1_06923001_1 - 5.1e-10 39.2 0.1 2.1e-05 24.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.4 001316244.1_06923001_1 - 1.2e-09 38.3 0.0 4.4e-05 23.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.4 001316244.1_06923001_1 - 2.3e-09 37.2 0.3 3e-07 30.5 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001316244.1_06923001_1 - 1.5e-07 31.0 0.0 0.0018 18.5 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat CBM_21 PF03370.11 001316244.1_06923001_1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) Fer4_13 PF13370.4 001316244.1_06923001_1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I CTP_transf_like PF01467.24 001315700.1_06923001_1 - 1.1e-32 113.1 0.0 2e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like WRKY PF03106.13 001316155.1_06924001_2 - 2.5e-50 168.5 15.2 7.2e-26 90.2 3.1 2.6 2 0 0 2 2 2 2 WRKY DNA -binding domain FAR1 PF03101.13 001316155.1_06924001_2 - 0.92 10.1 6.8 0.38 11.4 1.8 2.6 2 1 0 2 2 2 0 FAR1 DNA-binding domain GDI PF00996.16 001316077.1_06923001_1 - 3.4e-227 754.0 0.3 4.2e-227 753.7 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.22 001316077.1_06923001_1 - 1.7e-06 27.5 0.0 3.7e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Cellulose_synt PF03552.12 001315847.1_06927001_3 - 0 1359.0 0.0 0 1358.6 0.0 1.1 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001315847.1_06927001_3 - 2.4e-40 136.4 8.8 4.3e-40 135.6 8.8 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001315847.1_06927001_3 - 2.1e-08 34.2 0.1 2.1e-08 34.2 0.1 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001315847.1_06927001_3 - 6.1e-05 22.5 14.3 0.00012 21.6 14.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.14 001315847.1_06927001_3 - 0.0037 17.4 4.5 0.009 16.1 4.5 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Glyco_tranf_2_3 PF13641.4 001315847.1_06927001_3 - 0.033 13.9 0.0 0.87 9.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF3242 PF11586.6 001315847.1_06927001_3 - 0.14 11.8 0.9 0.32 10.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Prok-RING_1 PF14446.4 001315847.1_06927001_3 - 0.44 10.4 11.8 0.96 9.3 7.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 NAM PF02365.13 001315818.1_06922001_1 - 3.7e-27 94.9 0.1 5.9e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein Lipoprotein_6 PF01441.17 001316060.1_06923001_1 - 0.0032 17.2 16.0 0.023 14.4 1.3 3.1 1 1 2 3 3 3 3 Lipoprotein Pkinase PF00069.23 001315563.1_06924001_1 - 5e-75 252.1 0.0 7.5e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001315563.1_06924001_1 - 1.1e-32 109.0 11.5 3.1e-08 32.5 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001315563.1_06924001_1 - 2.1e-28 95.7 3.7 1.4e-07 30.7 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain Pkinase_Tyr PF07714.15 001315563.1_06924001_1 - 4.4e-27 94.9 0.0 6.4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001315563.1_06924001_1 - 2.3e-26 91.9 8.5 2.3e-12 47.0 1.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.4 001315563.1_06924001_1 - 1.8e-24 84.0 8.2 2.3e-06 26.7 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001315563.1_06924001_1 - 2.9e-20 71.6 12.7 1.1e-08 34.6 0.1 4.6 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.5 001315563.1_06924001_1 - 1.2e-08 34.6 1.7 0.002 17.9 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001315563.1_06924001_1 - 1.4e-07 31.6 0.3 0.0024 18.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.7 001315563.1_06924001_1 - 0.00011 22.4 0.3 0.17 12.1 0.1 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.12 001315563.1_06924001_1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001315563.1_06924001_1 - 0.00045 19.5 0.0 0.0019 17.5 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.21 001315563.1_06924001_1 - 0.0017 18.2 0.0 0.23 11.2 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_11 PF08976.9 001315563.1_06924001_1 - 0.027 15.2 0.1 8.9 7.1 0.0 2.6 2 1 1 3 3 2 0 EF-hand domain PMBR PF09373.8 001315563.1_06924001_1 - 0.05 13.6 0.1 1.2 9.2 0.0 3.4 4 0 0 4 4 4 0 Pseudomurein-binding repeat Caleosin PF05042.11 001315563.1_06924001_1 - 0.19 11.5 1.1 29 4.4 0.1 3.1 3 1 1 4 4 4 0 Caleosin related protein Aa_trans PF01490.16 001315799.1_06924001_1 - 1.9e-121 405.5 28.8 2.2e-121 405.3 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein BESS PF02944.18 001315799.1_06924001_1 - 0.11 12.2 1.1 0.18 11.5 0.2 1.9 2 0 0 2 2 2 0 BESS motif EF-hand_1 PF00036.30 001315842.1_06922001_1 - 2.3e-20 70.4 6.2 2.8e-06 26.4 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.4 001315842.1_06922001_1 - 3.3e-17 61.0 7.2 1.4e-07 30.6 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001315842.1_06922001_1 - 5.7e-15 53.8 6.5 0.002 17.8 0.4 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001315842.1_06922001_1 - 2.4e-14 53.4 10.3 3.7e-08 33.6 1.8 3.9 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_8 PF13833.4 001315842.1_06922001_1 - 3.9e-09 36.0 8.3 6.7e-05 22.4 0.7 3.6 3 2 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001315842.1_06922001_1 - 8.3e-05 22.7 2.6 0.0013 18.9 2.3 2.9 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001315842.1_06922001_1 - 0.0011 18.7 2.7 0.1 12.4 0.1 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Gemini_AL1 PF00799.18 001315842.1_06922001_1 - 0.017 15.2 0.3 0.038 14.0 0.3 1.6 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain DUF2247 PF10004.7 001315842.1_06922001_1 - 0.036 13.7 0.2 0.068 12.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) SHOCT PF09851.7 001315842.1_06922001_1 - 2.8 7.7 0.0 2.8 7.7 0.0 3.5 5 0 0 5 5 5 0 Short C-terminal domain Gln-synt_C PF00120.22 001316032.1_06923001_3 - 2.5e-15 56.2 0.0 4.5e-14 52.1 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001316032.1_06923001_3 - 9.3e-10 38.0 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain GST_N_3 PF13417.4 001316205.1_06922001_1 - 1.1e-16 60.8 0.0 1.9e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001316205.1_06922001_1 - 6e-16 58.4 0.0 1.2e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001316205.1_06922001_1 - 1e-12 47.7 0.1 2.3e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001316205.1_06922001_1 - 3.9e-10 39.7 0.7 6.7e-10 38.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001316205.1_06922001_1 - 1.3e-07 31.7 0.0 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.3 001316205.1_06922001_1 - 0.00062 20.2 0.0 0.00098 19.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001316205.1_06922001_1 - 0.0029 17.6 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.7 001316205.1_06922001_1 - 0.018 15.1 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.2 001316205.1_06922001_1 - 0.074 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain peroxidase PF00141.21 001315951.1_06926001_1 - 7.6e-69 231.8 0.0 1e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Caleosin PF05042.11 001315621.1_06922001_1 - 5.7e-75 250.8 0.0 7.3e-75 250.4 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein AP2 PF00847.18 001316074.1_06924001_1 - 6.9e-26 90.1 8.6 6.6e-13 48.6 3.0 2.8 2 0 0 2 2 2 2 AP2 domain HCO3_cotransp PF00955.19 001316231.1_06925001_1 - 3.7e-84 283.3 4.1 3.9e-36 124.9 2.1 3.1 2 1 1 3 3 3 3 HCO3- transporter family NAM PF02365.13 001316012.1_06923001_1 - 3.5e-27 94.9 0.3 5.9e-27 94.2 0.3 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein JIP_LZII PF16471.3 001316012.1_06923001_1 - 0.096 12.7 2.5 0.21 11.6 2.5 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II GIT_CC PF16559.3 001316012.1_06923001_1 - 2.5 8.0 6.6 0.21 11.5 1.1 2.1 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.10 001316012.1_06923001_1 - 4.5 7.7 8.1 1.5 9.2 0.3 3.1 2 1 1 3 3 3 0 Cell division protein ZapB NAM PF02365.13 001315819.1_06922001_1 - 2.8e-27 95.2 0.1 4.2e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein DUF3683 PF12447.6 001315819.1_06922001_1 - 0.00068 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3683) Tubulin PF00091.23 001316014.1_06924001_1 - 2.5e-67 226.8 0.0 3.4e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001316014.1_06924001_1 - 1.4e-49 167.4 0.0 2.1e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001316014.1_06924001_1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain LEA_2 PF03168.11 001315919.1_06923001_1 - 4.3e-11 43.1 0.0 6.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein NAM PF02365.13 001316041.1_06924001_1 - 8e-27 93.8 0.2 1.9e-26 92.6 0.2 1.6 1 0 0 1 1 1 1 No apical meristem (NAM) protein Myb_DNA-binding PF00249.29 001315751.1_06922001_2 - 1.2e-35 121.3 2.5 6.6e-17 61.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001315751.1_06922001_2 - 1.9e-22 79.1 0.7 1.6e-12 47.4 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001315751.1_06922001_2 - 0.00073 19.4 0.0 0.23 11.4 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.9 001315751.1_06922001_2 - 0.0037 17.3 0.0 0.86 9.7 0.0 2.3 2 0 0 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.3 001315751.1_06922001_2 - 0.013 15.2 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Myb DNA-binding like Rap1_C PF11626.6 001315751.1_06922001_2 - 0.058 13.4 0.3 0.57 10.2 0.3 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pkinase PF00069.23 001315977.1_06923001_1 - 4.6e-73 245.7 0.0 6.4e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315977.1_06923001_1 - 6e-35 120.7 0.0 7.6e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001315977.1_06923001_1 - 6.7e-07 28.7 0.1 1e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001315977.1_06923001_1 - 0.00018 20.8 0.0 0.0005 19.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.4 001315977.1_06923001_1 - 0.063 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.21 001315977.1_06923001_1 - 0.15 11.8 0.1 0.5 10.1 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family CBFD_NFYB_HMF PF00808.21 001315645.1_06922001_1 - 2.4e-26 91.7 0.3 3.4e-26 91.2 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001315645.1_06922001_1 - 4.3e-05 23.8 0.1 5.6e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.14 001315645.1_06922001_1 - 0.00063 19.6 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.4 001315645.1_06922001_1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.11 001315645.1_06922001_1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated NAM PF02365.13 001316239.1_06923001_1 - 2e-25 89.3 0.2 3.7e-25 88.4 0.2 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein Gln-synt_C PF00120.22 001315657.1_06923001_1 - 5.3e-17 61.7 0.0 1.2e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001315657.1_06923001_1 - 1.1e-10 40.9 0.0 2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SRF-TF PF00319.16 001315947.1_06922001_1 - 2e-24 84.7 0.1 5.1e-24 83.3 0.1 1.8 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001315947.1_06922001_1 - 6.1e-20 71.1 5.0 1.5e-19 69.9 5.0 1.6 1 0 0 1 1 1 1 K-box region DUF2721 PF11026.6 001315947.1_06922001_1 - 2.3 8.0 5.1 3.2 7.5 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) WRKY PF03106.13 001315850.1_06922001_1 - 1.7e-48 162.7 17.2 7.8e-25 86.9 5.9 2.3 2 0 0 2 2 2 2 WRKY DNA -binding domain FLYWCH PF04500.14 001315850.1_06922001_1 - 3.8 7.6 7.3 8.3 6.5 1.0 2.5 2 0 0 2 2 2 0 FLYWCH zinc finger domain WRKY PF03106.13 001316274.1_06922001_3 - 2.8e-23 81.9 6.1 4e-23 81.4 2.0 2.3 2 0 0 2 2 2 1 WRKY DNA -binding domain FAR1 PF03101.13 001316274.1_06922001_3 - 0.051 14.2 2.2 0.15 12.7 2.2 1.8 1 1 0 1 1 1 0 FAR1 DNA-binding domain Aldedh PF00171.20 001316187.1_06924001_1 - 8.7e-173 574.9 0.0 9.9e-173 574.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.9 001316187.1_06924001_1 - 0.032 13.5 0.0 5.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Epimerase PF01370.19 001316283.1_06923001_3 - 3.4e-25 88.8 0.0 4.5e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.4 001316283.1_06923001_3 - 1.9e-18 66.9 0.0 2.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.17 001316283.1_06923001_3 - 2.3e-18 66.1 0.0 3.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.11 001316283.1_06923001_3 - 7.1e-13 48.5 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.3 001316283.1_06923001_3 - 1.2e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.10 001316283.1_06923001_3 - 3.8e-09 36.0 0.0 4.6e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.13 001316283.1_06923001_3 - 1.2e-05 24.5 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.8 001316283.1_06923001_3 - 1.4e-05 25.0 0.0 4.4e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.23 001316283.1_06923001_3 - 0.00031 20.1 0.0 0.0029 17.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.16 001316283.1_06923001_3 - 0.02 15.0 0.0 0.083 13.0 0.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Myb_DNA-binding PF00249.29 001316042.1_06922001_1 - 2.4e-32 110.7 0.9 2.4e-15 56.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316042.1_06922001_1 - 2.8e-20 72.2 0.8 3e-12 46.5 0.0 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.8 001316042.1_06922001_1 - 0.012 15.5 0.0 0.76 9.7 0.0 2.5 2 1 0 2 2 2 0 SLIDE SRF-TF PF00319.16 001316048.1_06922001_1 - 3.5e-22 77.5 1.1 5.3e-22 76.9 0.4 1.7 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001316048.1_06922001_1 - 6.6e-18 64.6 11.9 1.3e-17 63.7 11.9 1.5 1 0 0 1 1 1 1 K-box region HALZ PF02183.16 001316048.1_06922001_1 - 0.0017 18.4 2.2 0.0017 18.4 2.2 2.6 3 0 0 3 3 3 1 Homeobox associated leucine zipper APG6 PF04111.10 001316048.1_06922001_1 - 0.038 13.3 4.2 0.052 12.8 4.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cnn_1N PF07989.9 001316048.1_06922001_1 - 0.046 13.7 6.2 0.15 12.1 6.2 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ANAPC4_WD40 PF12894.5 001316048.1_06922001_1 - 0.065 13.4 0.9 0.35 11.1 0.2 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DivIC PF04977.13 001316048.1_06922001_1 - 0.23 11.1 5.5 0.098 12.3 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.10 001316048.1_06922001_1 - 0.89 9.9 14.6 1.2 9.5 2.4 2.8 2 1 1 3 3 3 0 Cell division protein ZapB bZIP_1 PF00170.19 001316048.1_06922001_1 - 8 6.5 11.5 1.6 8.7 3.0 3.1 3 0 0 3 3 3 0 bZIP transcription factor DUF972 PF06156.11 001316048.1_06922001_1 - 8.9 6.9 12.1 2.9 8.4 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Pollen_allerg_1 PF01357.19 001316115.1_06922001_1 - 1.7e-24 85.5 1.5 2.8e-24 84.8 1.5 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001316115.1_06922001_1 - 6.3e-22 77.5 0.0 1.4e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase ERCC4 PF02732.13 001316152.1_06923001_1 - 0.0031 17.6 0.1 0.017 15.2 0.1 2.0 1 1 0 1 1 1 1 ERCC4 domain TraB PF01963.15 001316152.1_06923001_1 - 0.0066 16.3 0.1 0.021 14.6 0.1 1.8 1 1 0 1 1 1 1 TraB family adh_short PF00106.23 001316069.1_06923001_1 - 1.2e-30 106.3 0.0 3.6e-25 88.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.4 001316069.1_06923001_1 - 1.7e-17 63.7 0.0 5.3e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001316069.1_06923001_1 - 6.5e-11 42.3 0.2 2.5e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.19 001316069.1_06923001_1 - 0.0035 16.7 0.1 0.012 14.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.17 001316069.1_06923001_1 - 0.17 11.0 0.4 1.9 7.5 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain Pkinase PF00069.23 001316197.1_06923001_1 - 1.3e-62 211.5 0.0 1.9e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001316197.1_06923001_1 - 5.2e-32 106.9 9.9 1.9e-08 33.2 0.6 5.1 5 0 0 5 5 5 4 EF hand Pkinase_Tyr PF07714.15 001316197.1_06923001_1 - 1.1e-27 96.9 0.0 1.7e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001316197.1_06923001_1 - 2.2e-26 92.0 2.8 8.8e-14 51.6 1.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001316197.1_06923001_1 - 3e-26 88.9 3.3 2.8e-08 32.9 0.1 4.9 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.4 001316197.1_06923001_1 - 1.7e-21 75.6 8.0 6.6e-08 32.1 0.0 4.6 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.4 001316197.1_06923001_1 - 1.8e-20 71.3 3.2 0.00015 21.0 0.0 4.8 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001316197.1_06923001_1 - 6.4e-09 35.9 0.1 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001316197.1_06923001_1 - 2.2e-07 30.6 0.1 0.021 14.6 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.8 001316197.1_06923001_1 - 2.6e-06 27.3 0.4 0.11 12.5 0.0 2.7 3 0 0 3 3 2 2 Ca2+ insensitive EF hand Kdo PF06293.12 001316197.1_06923001_1 - 6.3e-05 22.3 0.2 0.00014 21.1 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.7 001316197.1_06923001_1 - 9e-05 22.6 0.1 0.062 13.5 0.1 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.4 001316197.1_06923001_1 - 0.0021 17.3 0.0 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001316197.1_06923001_1 - 0.063 13.1 0.1 0.87 9.3 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Caleosin PF05042.11 001316197.1_06923001_1 - 0.13 12.0 0.2 2.2 8.0 0.0 2.8 2 1 1 3 3 3 0 Caleosin related protein Pkinase PF00069.23 001315663.1_06924001_1 - 3.5e-67 226.4 0.0 4.8e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315663.1_06924001_1 - 1.4e-31 109.6 0.0 2.5e-31 108.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001315663.1_06924001_1 - 1.7e-07 30.6 0.5 3.1e-07 29.8 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001315663.1_06924001_1 - 0.0023 17.2 0.0 0.016 14.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like AP2 PF00847.18 001315820.1_06925001_3 - 2.2e-24 85.3 8.9 9.4e-12 44.9 4.1 2.6 2 0 0 2 2 2 2 AP2 domain Bax1-I PF01027.18 001315785.1_06923001_3 - 2.1e-37 128.9 15.7 2.7e-37 128.5 15.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PI3Ka PF00613.18 001316040.1_06925001_1 - 2.3e-64 216.1 5.1 4.3e-64 215.2 5.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.25 001316040.1_06925001_1 - 4.1e-49 167.5 0.0 2e-46 158.7 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.22 001316040.1_06925001_1 - 1.6e-41 141.4 0.0 2.9e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.28 001316040.1_06925001_1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 C2 domain DUF72 PF01904.16 001316040.1_06925001_1 - 0.094 12.7 0.3 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF72 LRR_8 PF13855.4 001316135.1_06923001_1 - 7e-15 54.4 17.5 1.5e-09 37.3 5.5 5.0 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.5 001316135.1_06923001_1 - 8.3e-13 48.1 19.9 5.5e-05 23.3 2.3 6.0 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001316135.1_06923001_1 - 6.7e-10 37.9 18.0 0.81 10.3 0.8 9.1 9 1 0 9 9 9 3 Leucine Rich Repeat LRRNT_2 PF08263.10 001316135.1_06923001_1 - 4.7e-09 36.3 0.6 4.7e-09 36.3 0.6 1.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.4 001316135.1_06923001_1 - 0.00075 19.2 13.6 7.7 6.7 0.1 8.1 8 0 0 8 8 8 1 Leucine Rich repeat FNIP PF05725.10 001316135.1_06923001_1 - 0.0013 18.7 0.9 1.1 9.3 0.0 3.7 3 1 0 3 3 3 1 FNIP Repeat Pkinase_Tyr PF07714.15 001316263.1_06923001_1 - 3.1e-63 213.3 0.0 4.7e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001316263.1_06923001_1 - 6.5e-50 169.8 0.0 8.6e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.4 001316263.1_06923001_1 - 1.9e-06 27.3 0.0 4.5e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001316263.1_06923001_1 - 0.089 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Macoilin PF09726.7 001316263.1_06923001_1 - 0.18 10.2 0.1 0.3 9.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein PRIMA1 PF16101.3 001316263.1_06923001_2 - 9.6 6.1 11.0 1.2 9.1 6.8 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 K-box PF01486.15 001315931.1_06922001_3 - 9.3e-29 99.3 9.5 2.2e-28 98.2 9.3 1.7 1 1 0 1 1 1 1 K-box region SRF-TF PF00319.16 001315931.1_06922001_3 - 1.5e-25 88.2 0.5 1.5e-25 88.2 0.5 1.8 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Het-C PF07217.9 001315931.1_06922001_3 - 0.049 12.0 2.7 0.066 11.6 2.7 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Exonuc_VII_L PF02601.13 001315931.1_06922001_3 - 0.93 8.9 5.7 1.3 8.4 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit NAM PF02365.13 001315583.1_06922001_1 - 5e-26 91.2 0.2 9e-26 90.4 0.2 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein WRC PF08879.8 001316085.1_06923001_1 - 1.2e-20 72.9 8.4 2.2e-20 72.0 8.4 1.5 1 0 0 1 1 1 1 WRC QLQ PF08880.9 001316085.1_06923001_1 - 2e-13 49.7 0.9 3.8e-13 48.8 0.9 1.5 1 0 0 1 1 1 1 QLQ zf-C3Hc3H PF13891.4 001316085.1_06923001_1 - 0.086 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Potential DNA-binding domain Gp_dh_C PF02800.18 001315584.1_06923001_2 - 1.1e-71 239.4 0.0 1.5e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001315584.1_06923001_2 - 6.9e-34 116.1 0.0 2.2e-33 114.5 0.0 1.9 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001315584.1_06923001_2 - 0.0016 18.4 0.3 0.0052 16.8 0.0 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.17 001315584.1_06923001_2 - 0.051 12.8 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lipase_3 PF01764.23 001315929.1_06924001_1 - 5.8e-40 136.3 0.0 8.6e-40 135.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.6 001315929.1_06924001_1 - 0.0025 17.3 0.1 0.2 11.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) DUF676 PF05057.12 001315929.1_06924001_1 - 0.005 16.2 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.5 001315929.1_06924001_1 - 0.057 13.9 0.6 0.12 12.8 0.2 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001315929.1_06924001_1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acyl-ACP_TE PF01643.15 001315669.1_06924001_1 - 7.8e-105 349.5 1.0 7.8e-105 349.5 1.0 1.4 2 0 0 2 2 2 1 Acyl-ACP thioesterase OAD_gamma PF04277.11 001315669.1_06924001_2 - 5.7 7.5 7.1 10 6.7 7.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Glyco_hydro_1 PF00232.16 001316199.1_06924001_1 - 2.6e-137 457.8 1.7 3.3e-137 457.5 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 MIP PF00230.18 001316255.1_06923001_2 - 9.1e-86 287.1 11.8 1.1e-85 286.8 11.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein MatE PF01554.16 001315683.1_06924001_1 - 8.2e-30 103.5 28.3 9e-14 51.3 14.5 3.4 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.4 001315683.1_06924001_1 - 3e-06 27.2 15.8 3e-06 27.2 15.8 3.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain Cu-oxidase PF00394.20 001316030.1_06924001_2 - 7.9e-40 136.4 0.2 2.4e-39 134.9 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.12 001316030.1_06924001_2 - 9.6e-39 132.1 0.5 1.7e-35 121.6 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.13 001316030.1_06924001_2 - 3.2e-38 130.3 3.4 6.4e-38 129.3 0.3 2.7 3 0 0 3 3 3 1 Multicopper oxidase Lyase_aromatic PF00221.17 001316275.1_06925001_3 - 1.9e-151 504.8 2.4 2.5e-151 504.4 2.4 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Glyco_hydro_1 PF00232.16 001315839.1_06924001_1 - 3.1e-137 457.6 1.8 4e-137 457.2 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Oxidored_molyb PF00174.17 001315920.1_06926001_1 - 3.1e-56 189.5 0.0 4.9e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.14 001315920.1_06926001_1 - 5.2e-56 188.3 0.2 9.3e-56 187.5 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.19 001315920.1_06926001_1 - 2.4e-33 114.9 0.0 5.4e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.22 001315920.1_06926001_1 - 2.5e-33 114.2 0.0 5.2e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.26 001315920.1_06926001_1 - 1.2e-24 86.1 0.1 4.9e-24 84.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.10 001315920.1_06926001_1 - 0.038 14.0 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Sulfate_transp PF00916.18 001316179.1_06925001_3 - 3.5e-134 447.2 20.3 4.5e-134 446.8 20.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001316179.1_06925001_3 - 4.1e-27 94.0 0.1 9.1e-27 92.9 0.1 1.6 1 0 0 1 1 1 1 STAS domain DUF4131 PF13567.4 001316179.1_06925001_3 - 0.015 14.8 1.5 0.015 14.8 1.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Glyco_hydro_1 PF00232.16 001315867.1_06924001_2 - 5.3e-137 456.8 2.0 6.8e-137 456.4 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Pkinase PF00069.23 001315739.1_06923001_1 - 1.1e-74 251.0 0.0 1.5e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315739.1_06923001_1 - 1.7e-38 132.3 0.0 2.4e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315739.1_06923001_1 - 2.7e-18 65.7 0.1 6.9e-18 64.4 0.1 1.7 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315739.1_06923001_1 - 1.3e-10 40.9 0.0 6.2e-10 38.7 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001315739.1_06923001_1 - 0.0029 16.9 0.0 0.0067 15.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001315739.1_06923001_1 - 0.01 15.6 0.1 0.93 9.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4926 PF16277.3 001315739.1_06923001_1 - 0.03 13.6 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) RIO1 PF01163.20 001315739.1_06923001_1 - 0.055 12.9 0.1 0.2 11.1 0.1 1.9 1 1 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.9 001315739.1_06923001_1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Myb_DNA-binding PF00249.29 001316049.1_06923001_1 - 2e-32 110.9 3.9 5e-17 61.6 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316049.1_06923001_1 - 8.5e-22 77.0 1.1 1.7e-12 47.3 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001316049.1_06923001_1 - 0.00065 19.6 0.5 0.051 13.5 0.0 3.0 2 1 1 3 3 3 1 SLIDE Organ_specific PF10950.6 001316049.1_06923001_1 - 0.091 13.3 0.6 3.5 8.2 0.1 2.5 2 1 0 2 2 2 0 Organ specific protein Catalase PF00199.17 001316210.1_06923001_1 - 1.3e-173 577.4 0.0 1.5e-173 577.2 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.10 001316210.1_06923001_1 - 3.3e-18 65.5 0.1 8.9e-18 64.1 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive HdeA PF06411.9 001316210.1_06923001_1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 HdeA/HdeB family Pkinase PF00069.23 001315707.1_06924001_1 - 2.4e-73 246.6 0.0 3.8e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001315707.1_06924001_1 - 6.1e-32 106.6 6.2 4e-07 29.0 0.9 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001315707.1_06924001_1 - 9.8e-27 90.5 0.8 1.6e-06 27.5 0.0 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.4 001315707.1_06924001_1 - 7.1e-26 90.3 3.1 8.6e-12 45.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.15 001315707.1_06924001_1 - 6.6e-25 87.7 0.0 1.2e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_5 PF13202.4 001315707.1_06924001_1 - 8.6e-25 85.0 5.2 9.4e-06 24.8 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001315707.1_06924001_1 - 1.4e-19 69.4 15.0 9.9e-07 28.3 0.2 5.0 2 1 3 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.4 001315707.1_06924001_1 - 8.9e-08 32.2 0.8 0.00017 21.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001315707.1_06924001_1 - 3.8e-07 29.9 1.3 0.0028 17.4 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.12 001315707.1_06924001_1 - 9.1e-06 25.0 0.1 1.9e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_11 PF08976.9 001315707.1_06924001_1 - 0.0011 19.6 0.0 1 10.2 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.7 001315707.1_06924001_1 - 0.0022 18.2 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.21 001315707.1_06924001_1 - 0.0051 16.6 0.1 1.7 8.4 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family tRNA_synt_1c_R1 PF04558.13 001315707.1_06924001_1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Kinase-like PF14531.4 001315707.1_06924001_1 - 0.018 14.2 0.1 1.5 8.0 0.1 3.0 2 1 0 2 2 2 0 Kinase-like DUF374 PF04028.11 001315707.1_06924001_1 - 0.063 12.7 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Oleosin PF01277.15 001315869.1_06922001_1 - 2.6e-39 133.3 1.9 3.9e-39 132.8 1.9 1.3 1 0 0 1 1 1 1 Oleosin DUF3487 PF11990.6 001315869.1_06922001_1 - 4.6 7.0 6.1 9.5 6.0 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) Radical_SAM_C PF16199.3 001315869.1_06922001_2 - 0.072 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Radical_SAM C-terminal domain ACCA PF03255.12 001315915.1_06926001_1 - 3.9e-55 185.5 0.0 3.9e-55 185.5 0.0 4.8 2 1 2 5 5 5 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.20 001315915.1_06926001_1 - 1.9e-08 33.3 0.0 4.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Carboxyl transferase domain HTH_1 PF00126.25 001315915.1_06926001_1 - 0.041 13.7 0.2 2.9 7.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF573 PF04504.12 001315915.1_06926001_1 - 2.6 8.6 11.8 9 6.9 0.7 4.4 2 1 1 3 3 3 0 Protein of unknown function, DUF573 bZIP_1 PF00170.19 001316167.1_06923001_1 - 1.2e-09 38.0 17.4 8.5e-09 35.3 6.7 2.8 1 1 2 3 3 3 3 bZIP transcription factor bZIP_2 PF07716.13 001316167.1_06923001_1 - 4.9e-07 29.6 4.7 4.9e-07 29.6 4.7 2.9 1 1 2 3 3 3 1 Basic region leucine zipper ADIP PF11559.6 001316167.1_06923001_1 - 3.3e-05 23.9 8.3 6e-05 23.0 8.3 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.4 001316167.1_06923001_1 - 0.0011 18.8 5.9 0.002 17.9 5.9 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.3 001316167.1_06923001_1 - 0.0015 18.4 1.4 0.0015 18.4 1.4 1.9 1 1 1 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_Maf PF03131.15 001316167.1_06923001_1 - 0.0046 17.3 7.3 0.0046 17.3 7.3 2.8 2 1 1 3 3 3 1 bZIP Maf transcription factor Spc7 PF08317.9 001316167.1_06923001_1 - 0.0052 15.6 3.9 0.0093 14.8 3.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.9 001316167.1_06923001_1 - 0.0052 15.6 4.3 0.0065 15.3 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF972 PF06156.11 001316167.1_06923001_1 - 0.0062 17.0 3.3 0.013 16.0 3.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) ATG16 PF08614.9 001316167.1_06923001_1 - 0.02 15.0 15.1 0.035 14.1 14.9 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.12 001316167.1_06923001_1 - 0.021 14.5 6.1 0.033 13.8 6.1 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.10 001316167.1_06923001_1 - 0.1 11.9 6.0 0.15 11.3 6.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3450 PF11932.6 001316167.1_06923001_1 - 0.11 11.7 6.9 0.16 11.1 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.10 001316167.1_06923001_1 - 0.15 12.4 14.2 0.64 10.4 14.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapB HAUS-augmin3 PF14932.4 001316167.1_06923001_1 - 0.19 11.1 9.5 0.3 10.4 9.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.10 001316167.1_06923001_1 - 0.25 11.8 7.9 0.59 10.7 7.6 1.8 1 1 0 1 1 1 0 SlyX Cep57_MT_bd PF06657.11 001316167.1_06923001_1 - 0.29 11.5 6.6 1 9.7 2.7 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.10 001316167.1_06923001_1 - 0.37 10.7 2.9 0.6 10.0 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.17 001316167.1_06923001_1 - 0.85 7.3 3.1 1.2 6.8 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnn_1N PF07989.9 001316167.1_06923001_1 - 1.7 8.7 9.6 0.88 9.6 3.0 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 PLD_C PF12357.6 001315848.1_06925001_1 - 1.3e-27 95.3 0.0 2.6e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.20 001315848.1_06925001_1 - 7.1e-20 70.2 0.6 3.2e-10 39.6 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif C2 PF00168.28 001315848.1_06925001_1 - 3.2e-13 49.7 0.0 8.8e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain PLDc_2 PF13091.4 001315848.1_06925001_1 - 5.5e-11 42.3 0.0 1.9e-07 30.9 0.1 3.5 2 2 0 2 2 2 2 PLD-like domain p450 PF00067.20 001315861.1_06924001_1 - 3.3e-111 372.1 0.0 3.9e-111 371.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_2 PF13347.4 001316121.1_06924001_1 - 9.3e-12 44.1 5.7 9.3e-12 44.1 5.7 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein Sulfate_transp PF00916.18 001315588.1_06925001_1 - 6.4e-136 452.9 17.5 8.6e-136 452.5 17.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001315588.1_06925001_1 - 8.3e-27 93.0 0.0 2.6e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.4 001315588.1_06925001_1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 STAS domain Glyco_hydro_28 PF00295.15 001315566.1_06923001_1 - 5.8e-123 410.0 7.1 6.8e-123 409.7 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.4 001315566.1_06923001_1 - 0.00014 21.6 2.3 0.00014 21.6 2.3 2.0 1 1 1 2 2 2 2 Right handed beta helix region Pectate_lyase_3 PF12708.5 001315566.1_06923001_1 - 0.00019 21.3 2.1 0.00068 19.5 0.8 2.2 2 1 0 2 2 2 1 Pectate lyase superfamily protein AsmA_2 PF13502.4 001315566.1_06923001_1 - 0.026 13.9 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 AsmA-like C-terminal region NosD PF05048.11 001315566.1_06923001_1 - 0.041 13.0 0.2 0.065 12.4 0.2 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) WRC PF08879.8 001316174.1_06923001_1 - 2.7e-21 74.9 8.4 4.9e-21 74.1 8.4 1.5 1 0 0 1 1 1 1 WRC QLQ PF08880.9 001316174.1_06923001_1 - 1.9e-13 49.8 0.9 3.7e-13 48.8 0.9 1.5 1 0 0 1 1 1 1 QLQ zf-C3Hc3H PF13891.4 001316174.1_06923001_1 - 0.13 12.5 0.2 0.31 11.3 0.2 1.6 1 0 0 1 1 1 0 Potential DNA-binding domain SRF-TF PF00319.16 001315897.1_06922001_1 - 1.9e-26 91.1 0.3 3.4e-26 90.3 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001315897.1_06922001_1 - 9.5e-17 60.8 12.9 9.5e-17 60.8 12.9 2.3 1 1 1 2 2 2 1 K-box region NRBF2 PF08961.8 001315897.1_06922001_1 - 0.00051 19.6 2.1 0.00051 19.6 2.1 2.1 1 1 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator Sipho_Gp157 PF05565.9 001315897.1_06922001_1 - 0.098 12.5 11.2 0.068 13.0 7.7 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 bZIP_1 PF00170.19 001315897.1_06922001_1 - 0.44 10.5 8.7 0.13 12.3 1.3 3.2 1 1 2 3 3 3 0 bZIP transcription factor Prominin PF05478.9 001315897.1_06922001_1 - 1.2 6.9 5.6 1.4 6.6 5.6 1.1 1 0 0 1 1 1 0 Prominin ZapB PF06005.10 001315897.1_06922001_1 - 6.1 7.2 18.6 1.1 9.6 8.8 2.8 1 1 1 2 2 2 0 Cell division protein ZapB APG6 PF04111.10 001315897.1_06922001_1 - 7.4 5.7 13.2 13 4.9 13.2 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.11 001315897.1_06922001_1 - 7.8 7.0 13.0 0.43 11.1 5.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PI-PLC-X PF00388.17 001315824.1_06924001_1 - 2.6e-51 172.9 0.0 4e-51 172.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.17 001315824.1_06924001_1 - 2.5e-29 101.9 0.0 4.4e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.28 001315824.1_06924001_1 - 1.5e-09 37.9 0.0 3.9e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.9 001315824.1_06924001_1 - 1.9e-05 24.9 1.9 7.6e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF2264 PF10022.7 001315824.1_06924001_1 - 0.13 11.2 0.1 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2264) HTH_23 PF13384.4 001315675.1_06923001_1 - 0.034 13.8 0.0 0.089 12.5 0.0 1.7 1 1 0 1 1 1 0 Homeodomain-like domain FBPase PF00316.18 001315675.1_06923001_2 - 1.7e-83 278.7 0.1 2.9e-83 277.9 0.1 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Big_3 PF07523.10 001315675.1_06923001_2 - 0.056 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Inositol_P PF00459.23 001315675.1_06923001_2 - 0.078 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family Thiolase_N PF00108.21 001315753.1_06923001_1 - 1.1e-78 264.1 0.3 1.4e-78 263.7 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.16 001315753.1_06923001_1 - 3.1e-48 162.4 0.9 5.4e-48 161.6 0.9 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.8 001315753.1_06923001_1 - 0.0024 17.8 0.2 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF834 PF05754.12 001315753.1_06923001_1 - 0.18 11.9 2.0 0.39 10.8 0.1 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF834) WRKY PF03106.13 001315822.1_06923001_2 - 6.5e-27 93.5 0.6 6.5e-27 93.5 0.6 1.8 2 0 0 2 2 2 1 WRKY DNA -binding domain Plant_zn_clust PF10533.7 001315822.1_06923001_2 - 7.4e-16 57.7 7.4 1.6e-15 56.6 7.4 1.6 1 0 0 1 1 1 1 Plant zinc cluster domain Peptidase_C1 PF00112.21 001315991.1_06923001_1 - 5e-78 262.0 0.5 6.7e-78 261.6 0.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001315991.1_06923001_1 - 3.8e-14 52.7 1.7 5.8e-14 52.1 1.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 001315991.1_06923001_1 - 5.6e-06 25.3 0.8 0.00049 18.8 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Myb_DNA-binding PF00249.29 001316003.1_06923001_1 - 2.2e-32 110.8 3.3 2e-17 62.9 0.8 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316003.1_06923001_1 - 6.3e-22 77.5 0.5 3.9e-12 46.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001316003.1_06923001_1 - 0.0035 17.2 0.0 0.11 12.4 0.0 2.5 1 1 1 2 2 2 1 SLIDE WRKY PF03106.13 001315866.1_06923001_2 - 7.1e-27 93.4 0.7 1.5e-26 92.4 0.7 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain Plant_zn_clust PF10533.7 001315866.1_06923001_2 - 3e-17 62.1 8.4 6.6e-17 61.0 8.4 1.6 1 0 0 1 1 1 1 Plant zinc cluster domain 14-3-3 PF00244.18 001315550.1_06923001_1 - 5.5e-100 333.3 2.3 6.5e-100 333.0 2.3 1.1 1 0 0 1 1 1 1 14-3-3 protein PhoU_div PF01865.14 001315550.1_06923001_1 - 0.028 13.6 0.3 2.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF47 IPPT PF01715.15 001316036.1_06924001_1 - 2.5e-50 171.3 0.0 5.7e-50 170.1 0.0 1.6 2 0 0 2 2 2 1 IPP transferase IPT PF01745.14 001316036.1_06924001_1 - 9.3e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase DUF3449 PF11931.6 001316036.1_06924001_1 - 0.00037 20.2 0.6 0.00083 19.1 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Cas9-BH PF16593.3 001316036.1_06924001_1 - 0.00046 19.7 1.5 0.00046 19.7 1.5 2.1 2 0 0 2 2 2 1 Bridge helix of CRISPR-associated endonuclease Cas9 AAA_33 PF13671.4 001316036.1_06924001_1 - 0.00062 19.8 0.1 0.0023 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.4 001316036.1_06924001_1 - 0.001 19.2 0.0 0.0044 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.15 001316036.1_06924001_1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Cytidylate_kin PF02224.16 001316036.1_06924001_1 - 0.0024 17.5 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.20 001316036.1_06924001_1 - 0.0049 17.1 0.1 0.4 11.0 0.0 3.0 3 0 0 3 3 3 1 RNA helicase Adeno_IVa2 PF02456.13 001316036.1_06924001_1 - 0.011 14.4 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein PhoH PF02562.14 001316036.1_06924001_1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.4 001316036.1_06924001_1 - 0.013 15.9 0.1 0.054 13.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.25 001316036.1_06924001_1 - 0.016 15.6 0.1 0.048 14.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter DUF258 PF03193.14 001316036.1_06924001_1 - 0.017 14.9 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NPH3 PF03000.12 001316036.1_06924001_1 - 0.029 14.1 0.1 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 NPH3 family AAA PF00004.27 001316036.1_06924001_1 - 0.054 13.8 0.2 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.4 001316036.1_06924001_1 - 0.063 12.7 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.4 001316036.1_06924001_1 - 0.083 12.5 0.1 0.24 11.0 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C2H2_jaz PF12171.6 001316036.1_06924001_1 - 0.09 13.0 0.2 0.09 13.0 0.2 2.4 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding SBP_bac_1 PF01547.23 001316036.1_06924001_1 - 0.28 11.0 0.5 17 5.1 0.1 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein DUF87 PF01935.15 001316036.1_06924001_1 - 8.3 6.2 7.3 21 4.9 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function DUF87 K-box PF01486.15 001315685.1_06922001_1 - 3.1e-28 97.7 8.5 6.1e-28 96.7 8.5 1.5 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001315685.1_06922001_1 - 3.5e-26 90.3 0.2 5.8e-26 89.6 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AKAP2_C PF15304.4 001315685.1_06922001_1 - 0.004 16.3 0.7 0.005 16.0 0.7 1.2 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus DUF1192 PF06698.9 001315685.1_06922001_1 - 0.17 11.8 0.9 1.4 8.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) TSC22 PF01166.16 001315685.1_06922001_1 - 0.26 11.5 2.9 2.8 8.2 0.5 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family GIT_CC PF16559.3 001315685.1_06922001_1 - 0.47 10.4 6.7 0.98 9.4 2.8 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2721 PF11026.6 001315685.1_06922001_1 - 1.5 8.6 4.4 5.8 6.7 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) NAM PF02365.13 001315775.1_06923001_2 - 1e-26 93.5 0.1 1.9e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein MatE PF01554.16 001315837.1_06924001_2 - 9.2e-51 171.6 39.8 6.2e-28 97.3 17.9 2.7 4 0 0 4 4 4 2 MatE Acyltransferase PF01553.19 001316301.1_06923001_1 - 1.3e-22 79.8 0.0 2.1e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.3 001316301.1_06923001_1 - 9.8e-19 67.2 0.0 1.8e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus ThrE PF06738.10 001316301.1_06923001_1 - 0.24 10.6 2.9 8.3 5.6 1.8 2.2 2 0 0 2 2 2 0 Putative threonine/serine exporter PTR2 PF00854.19 001315634.1_06925001_2 - 2.4e-126 421.6 2.5 2.4e-126 421.6 2.5 1.6 2 0 0 2 2 2 1 POT family BT1 PF03092.14 001315634.1_06925001_2 - 0.0063 14.7 3.9 0.11 10.5 0.0 2.6 3 0 0 3 3 3 2 BT1 family Caleosin PF05042.11 001316035.1_06922001_1 - 6.2e-76 253.9 0.0 7.9e-76 253.6 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein Abhydrolase_1 PF00561.18 001315966.1_06922001_1 - 1.3e-22 80.6 0.3 2.3e-22 79.7 0.2 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001315966.1_06922001_1 - 9.3e-19 68.8 0.2 1.4e-18 68.1 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001315966.1_06922001_1 - 7.5e-12 44.9 0.0 7.4e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_2 PF01674.16 001315966.1_06922001_1 - 0.021 14.2 0.0 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 2) Chlorophyllase2 PF12740.5 001315966.1_06922001_1 - 0.032 13.0 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.16 001315966.1_06922001_1 - 0.13 11.7 0.0 1.3 8.3 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family SRF-TF PF00319.16 001316203.1_06922001_1 - 2.5e-22 78.0 0.7 5.3e-22 76.9 0.4 1.8 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001316203.1_06922001_1 - 1.5e-17 63.4 12.5 2.8e-17 62.6 12.5 1.5 1 0 0 1 1 1 1 K-box region HALZ PF02183.16 001316203.1_06922001_1 - 0.0017 18.4 2.2 0.0017 18.4 2.2 2.6 3 0 0 3 3 3 1 Homeobox associated leucine zipper APG6 PF04111.10 001316203.1_06922001_1 - 0.0092 15.3 3.6 0.012 14.9 3.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Cnn_1N PF07989.9 001316203.1_06922001_1 - 0.06 13.3 6.3 0.21 11.6 6.3 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ANAPC4_WD40 PF12894.5 001316203.1_06922001_1 - 0.071 13.3 0.7 0.4 10.9 0.1 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ZapB PF06005.10 001316203.1_06922001_1 - 0.19 12.0 15.6 0.42 10.9 2.2 2.8 2 1 1 3 3 3 0 Cell division protein ZapB DivIC PF04977.13 001316203.1_06922001_1 - 0.25 11.0 6.8 0.098 12.3 1.2 2.5 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.19 001316203.1_06922001_1 - 6.8 6.7 11.2 1.6 8.7 3.0 3.1 3 0 0 3 3 3 0 bZIP transcription factor Epimerase PF01370.19 001316237.1_06923001_1 - 3.5e-23 82.2 0.0 4.8e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001316237.1_06923001_1 - 4e-15 55.4 0.0 5.6e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001316237.1_06923001_1 - 5e-13 49.3 0.0 7.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.3 001316237.1_06923001_1 - 5.6e-12 45.5 0.0 1.1e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.10 001316237.1_06923001_1 - 5e-08 32.3 0.0 2.1e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.11 001316237.1_06923001_1 - 4.7e-07 29.5 0.0 7.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.23 001316237.1_06923001_1 - 2.7e-05 23.6 0.0 0.00011 21.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001316237.1_06923001_1 - 0.0048 16.7 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Myb_CC_LHEQLE PF14379.4 001315671.1_06923001_1 - 2.9e-24 84.4 13.3 2.9e-24 84.4 13.3 1.7 2 0 0 2 2 2 1 MYB-CC type transfactor, LHEQLE motif Myb_DNA-binding PF00249.29 001315671.1_06923001_1 - 4.8e-10 39.3 0.0 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SKA1 PF07160.10 001315671.1_06923001_1 - 0.73 9.5 12.9 0.056 13.2 7.0 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 WRKY PF03106.13 001316043.1_06924001_1 - 1.9e-50 168.9 14.2 4.2e-26 90.9 2.9 2.5 2 0 0 2 2 2 2 WRKY DNA -binding domain AP2 PF00847.18 001316209.1_06924001_3 - 2.2e-24 85.4 8.9 9.3e-12 44.9 4.1 2.6 2 0 0 2 2 2 2 AP2 domain PP2C PF00481.19 001316061.1_06924001_1 - 1.5e-60 204.9 0.0 2.7e-60 204.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001316061.1_06924001_1 - 0.043 13.3 0.0 0.15 11.5 0.0 2.0 1 1 1 2 2 2 0 Protein phosphatase 2C tify PF06200.12 001316061.1_06924001_2 - 0.088 12.0 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 tify domain NAM PF02365.13 001315559.1_06922001_1 - 5.1e-24 84.8 0.1 9.4e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein Pkinase PF00069.23 001315665.1_06923001_1 - 5.2e-71 239.0 0.0 7.5e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315665.1_06923001_1 - 7e-38 130.3 0.0 1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315665.1_06923001_1 - 5.9e-22 77.5 1.5 1.3e-21 76.4 1.5 1.6 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315665.1_06923001_1 - 7.3e-08 31.9 0.0 1.7e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001315665.1_06923001_1 - 0.00042 19.6 0.1 0.00074 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KA1 PF02149.17 001315665.1_06923001_1 - 0.014 15.1 0.0 0.053 13.2 0.0 2.0 2 0 0 2 2 2 0 Kinase associated domain 1 APH PF01636.21 001315665.1_06923001_1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family mTERF PF02536.12 001315985.1_06922001_1 - 7.8e-40 136.6 1.4 2.1e-26 92.5 0.4 2.2 1 1 1 2 2 2 2 mTERF HAD PF12710.5 001315723.1_06924001_2 - 4.6e-14 53.1 0.0 6.4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.19 001315723.1_06924001_2 - 9.8e-08 31.6 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Pkinase_Tyr PF07714.15 001315801.1_06924001_1 - 2.5e-72 243.2 0.1 3.4e-72 242.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001315801.1_06924001_1 - 1.7e-58 197.9 0.0 2.6e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ACT PF01842.23 001315801.1_06924001_1 - 1.7e-06 27.6 0.0 3.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 ACT domain APH PF01636.21 001315801.1_06924001_1 - 0.0015 18.3 1.1 0.25 11.1 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.4 001315801.1_06924001_1 - 0.0061 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ACT_6 PF13740.4 001315801.1_06924001_1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 ACT domain NAM PF02365.13 001315922.1_06923001_1 - 7e-26 90.8 0.1 1.2e-25 90.0 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein Metallophos PF00149.26 001315939.1_06923001_2 - 2.4e-16 60.7 0.9 3.2e-16 60.3 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NAM PF02365.13 001316214.1_06923001_1 - 6.9e-28 97.2 0.1 1.2e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein HAD PF12710.5 001316016.1_06924001_3 - 4.3e-14 53.2 0.0 6.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.19 001316016.1_06924001_3 - 6.9e-08 32.1 0.0 1.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.23 001316230.1_06924001_1 - 4.2e-74 249.1 0.0 6e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001316230.1_06924001_1 - 5.5e-31 103.6 7.8 1e-08 34.0 0.2 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001316230.1_06924001_1 - 1.5e-25 89.8 0.0 2.5e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001316230.1_06924001_1 - 9.1e-25 86.8 5.3 5e-14 52.4 1.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001316230.1_06924001_1 - 1.4e-24 83.7 3.2 4.1e-06 26.2 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.4 001316230.1_06924001_1 - 5.7e-24 83.5 8.1 2e-07 30.5 0.0 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.4 001316230.1_06924001_1 - 5.6e-22 76.1 2.5 1.6e-07 30.4 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.4 001316230.1_06924001_1 - 1e-06 28.8 0.4 9.9e-05 22.5 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.7 001316230.1_06924001_1 - 2.6e-06 27.6 0.4 0.1 12.8 0.2 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.11 001316230.1_06924001_1 - 9.5e-06 25.5 0.1 0.55 10.0 0.0 3.3 1 1 2 3 3 3 2 Caleosin related protein Kinase-like PF14531.4 001316230.1_06924001_1 - 5.1e-05 22.6 0.0 0.00031 20.0 0.0 2.1 1 1 0 1 1 1 1 Kinase-like EF-hand_4 PF12763.5 001316230.1_06924001_1 - 0.00032 20.5 1.3 0.51 10.2 0.1 2.7 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.8 001316230.1_06924001_1 - 0.00051 19.9 0.2 0.37 10.8 0.0 2.5 2 0 0 2 2 2 2 Ca2+ insensitive EF hand Kdo PF06293.12 001316230.1_06924001_1 - 0.0011 18.2 0.1 0.0026 17.0 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_10 PF14788.4 001316230.1_06924001_1 - 0.0064 16.2 0.1 2.7 7.8 0.0 2.8 2 1 0 2 2 2 1 EF hand APH PF01636.21 001316230.1_06924001_1 - 0.01 15.6 0.0 0.12 12.1 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.20 001316230.1_06924001_1 - 0.11 12.0 0.8 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Myb_DNA-binding PF00249.29 001316020.1_06923001_3 - 4.2e-32 109.9 1.9 1.3e-15 57.1 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001316020.1_06923001_3 - 5.4e-21 74.5 0.6 9.2e-13 48.1 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001316020.1_06923001_3 - 0.0046 16.7 0.0 0.025 14.3 0.0 2.2 1 1 1 2 2 2 1 Myb DNA-binding like DUF3695 PF12494.6 001316020.1_06923001_3 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) p450 PF00067.20 001315856.1_06924001_1 - 5.7e-98 328.5 0.0 7e-98 328.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyridoxal_deC PF00282.17 001316081.1_06924001_3 - 2.5e-24 85.6 0.0 5.2e-24 84.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain NAM PF02365.13 001316093.1_06923001_1 - 4.8e-27 94.5 0.1 7.7e-27 93.8 0.1 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein SRF-TF PF00319.16 001316008.1_06922001_1 - 1.1e-25 88.7 0.2 1.8e-25 88.0 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001316008.1_06922001_1 - 3.6e-16 59.0 12.3 6.6e-16 58.1 12.3 1.4 1 0 0 1 1 1 1 K-box region NicO PF03824.14 001316008.1_06922001_1 - 0.041 13.1 1.1 0.075 12.2 1.1 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein CO_dh PF02552.14 001316008.1_06922001_1 - 0.072 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Carbpep_Y_N PF05388.9 001316008.1_06922001_1 - 0.11 12.9 1.3 0.17 12.3 1.3 1.4 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide DUF4239 PF14023.4 001316008.1_06922001_1 - 0.24 11.0 1.0 0.4 10.3 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DUF2390 PF09523.8 001316008.1_06922001_1 - 3.7 7.8 7.7 1.3 9.2 1.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2390) Lipase_GDSL PF00657.20 001315890.1_06923001_3 - 7.1e-25 88.0 0.0 8.7e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAD_binding_7 PF03441.12 001316031.1_06925001_2 - 1e-60 204.4 0.2 2.7e-60 203.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.16 001316031.1_06925001_2 - 1.2e-40 139.0 0.0 2.1e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Cryptochrome_C PF12546.6 001316031.1_06925001_2 - 6.9e-30 104.2 10.0 1.2e-29 103.5 10.0 1.3 1 0 0 1 1 1 1 Blue/Ultraviolet sensing protein C terminal DUF3709 PF12493.6 001316221.1_06922001_1 - 0.018 15.0 6.2 0.041 13.8 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3709) LEA_4 PF02987.14 001316221.1_06922001_3 - 4.6e-08 32.9 70.3 0.0021 18.0 14.6 5.2 3 1 2 5 5 5 4 Late embryogenesis abundant protein YtxH PF12732.5 001316221.1_06922001_3 - 0.00039 20.8 42.9 0.39 11.1 13.8 3.6 1 1 2 3 3 3 3 YtxH-like protein Apolipoprotein PF01442.16 001316221.1_06922001_3 - 0.0005 19.9 38.0 0.0018 18.1 37.9 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.11 001316221.1_06922001_3 - 0.0016 18.8 40.2 0.42 11.1 14.2 3.6 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) LAP1C PF05609.10 001316221.1_06922001_3 - 0.054 12.5 26.5 0.072 12.1 26.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Mitofilin PF09731.7 001316221.1_06922001_3 - 0.33 9.6 41.2 0.41 9.3 41.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.7 001316221.1_06922001_3 - 0.66 8.3 20.8 0.74 8.2 20.8 1.2 1 0 0 1 1 1 0 Transmembrane protein CAML PF14963.4 001316221.1_06922001_3 - 3.5 7.5 18.2 6 6.8 18.2 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand GREB1 PF15782.3 001316221.1_06922001_3 - 8.2 3.3 26.4 9.3 3.1 26.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SQS_PSY PF00494.17 001315932.1_06924001_2 - 1.2e-73 247.7 1.8 1.8e-73 247.2 1.2 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase NAM PF02365.13 001316064.1_06922001_1 - 6.8e-30 103.6 1.0 1.2e-29 102.9 1.0 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein K-box PF01486.15 001316058.1_06922001_1 - 2.5e-27 94.8 9.7 5.3e-27 93.7 9.7 1.5 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001316058.1_06922001_1 - 5e-26 89.8 0.1 5e-26 89.8 0.1 2.4 3 0 0 3 3 3 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Rootletin PF15035.4 001316058.1_06922001_1 - 0.0086 16.0 10.5 0.013 15.4 10.5 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Speriolin_C PF15059.4 001316058.1_06922001_1 - 0.025 14.6 1.1 0.039 13.9 0.1 1.7 2 0 0 2 2 2 0 Speriolin C-terminus Fzo_mitofusin PF04799.11 001316058.1_06922001_1 - 0.089 12.2 0.2 0.089 12.2 0.2 2.4 3 0 0 3 3 3 0 fzo-like conserved region Proteasome_A_N PF10584.7 001316058.1_06922001_1 - 0.096 12.2 0.8 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature ARA70 PF12489.6 001316058.1_06922001_1 - 0.13 12.3 8.4 0.078 13.0 5.1 2.1 2 0 0 2 2 2 0 Nuclear coactivator DUF4747 PF15931.3 001316058.1_06922001_1 - 0.14 11.4 6.6 0.068 12.4 3.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4747) TCTP PF00838.15 001316058.1_06922001_1 - 0.16 12.1 0.3 0.16 12.1 0.3 2.0 2 1 0 2 2 2 0 Translationally controlled tumour protein DUF972 PF06156.11 001316058.1_06922001_1 - 0.21 12.1 9.1 0.4 11.2 4.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HIP1_clath_bdg PF16515.3 001316058.1_06922001_1 - 0.96 10.0 13.5 0.97 9.9 6.4 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3393 PF11873.6 001316058.1_06922001_1 - 1.2 8.7 8.1 4.8 6.7 8.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3393) DUF3450 PF11932.6 001316058.1_06922001_1 - 2.5 7.2 10.7 1.3 8.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.19 001316058.1_06922001_1 - 2.7 8.0 14.8 2.4 8.2 7.2 2.7 2 1 0 2 2 2 0 bZIP transcription factor DUF2203 PF09969.7 001316058.1_06922001_1 - 3.4 8.3 7.7 17 6.0 4.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) HSP70 PF00012.18 001316218.1_06925001_1 - 2.4e-264 878.0 12.3 2.7e-264 877.8 12.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001316218.1_06925001_1 - 1.1e-17 63.7 0.4 2.9e-16 59.1 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.14 001316218.1_06925001_1 - 0.0042 16.7 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.16 001316218.1_06925001_1 - 0.0075 15.4 1.7 0.079 12.1 0.1 2.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase HOIP-UBA PF16678.3 001316218.1_06925001_1 - 0.014 15.3 3.4 0.031 14.2 0.0 2.4 2 0 0 2 2 2 0 UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase FtsA PF14450.4 001316218.1_06925001_1 - 0.019 15.2 6.0 0.45 10.8 0.2 3.7 3 2 0 3 3 3 0 Cell division protein FtsA DDR PF08841.8 001316218.1_06925001_1 - 0.028 13.3 0.4 0.21 10.4 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Radial_spoke_3 PF06098.9 001316218.1_06925001_1 - 0.033 13.4 12.4 0.017 14.3 10.2 1.5 2 0 0 2 2 2 0 Radial spoke protein 3 Cellulose_synt PF03552.12 001316065.1_06927001_2 - 0 1323.2 9.1 0 1319.0 9.1 2.0 1 1 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.4 001316065.1_06927001_2 - 6.1e-41 138.3 5.6 1.2e-40 137.3 5.6 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger Glyco_trans_2_3 PF13632.4 001316065.1_06927001_2 - 2.6e-07 30.6 0.2 2.6e-07 30.6 0.2 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 zf-RING_4 PF14570.4 001316065.1_06927001_2 - 2.9e-05 23.6 10.6 6.1e-05 22.5 10.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.4 001316065.1_06927001_2 - 0.00098 18.9 3.5 0.00098 18.9 3.5 2.3 1 1 0 2 2 2 1 Prokaryotic RING finger family 1 Glycos_transf_2 PF00535.24 001316065.1_06927001_2 - 0.0013 18.4 0.1 0.0073 16.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.4 001316065.1_06927001_2 - 0.0093 15.8 0.1 0.27 11.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 FYVE_2 PF02318.14 001316065.1_06927001_2 - 0.016 15.3 2.2 0.03 14.4 2.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Baculo_IE-1 PF05290.9 001316065.1_06927001_2 - 0.16 11.8 1.3 0.34 10.7 1.3 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_9 PF13901.4 001316065.1_06927001_2 - 0.89 9.3 4.8 1.4 8.7 4.8 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Exo70 PF03081.13 001315704.1_06924001_1 - 2.7e-121 405.1 3.0 1.7e-120 402.5 0.5 2.1 2 0 0 2 2 2 2 Exo70 exocyst complex subunit Sec34 PF04136.13 001315704.1_06924001_1 - 0.0026 17.5 2.2 0.0026 17.5 2.2 2.1 2 0 0 2 2 2 1 Sec34-like family Globin PF00042.20 001315704.1_06924001_1 - 0.12 12.8 0.9 1.6 9.2 0.1 2.8 2 0 0 2 2 2 0 Globin Myb_DNA-binding PF00249.29 001315542.1_06923001_2 - 5.8e-34 115.9 4.6 8.3e-17 60.9 0.4 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001315542.1_06923001_2 - 1.8e-21 76.0 2.1 1.7e-12 47.3 0.1 3.6 3 1 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.8 001315542.1_06923001_2 - 0.014 15.3 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 SLIDE Epimerase PF01370.19 001315585.1_06923001_3 - 1.2e-23 83.8 0.0 1.5e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001315585.1_06923001_3 - 1.2e-18 67.0 0.0 1.6e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001315585.1_06923001_3 - 1.8e-17 63.7 0.0 2.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.11 001315585.1_06923001_3 - 2.7e-12 46.6 0.0 4.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.3 001315585.1_06923001_3 - 1.4e-10 40.9 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.10 001315585.1_06923001_3 - 9.1e-09 34.7 0.0 1.6e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.13 001315585.1_06923001_3 - 2.2e-05 23.6 0.0 3.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.8 001315585.1_06923001_3 - 4.4e-05 23.3 0.0 0.00015 21.6 0.0 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.23 001315585.1_06923001_3 - 0.001 18.4 0.0 0.0093 15.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Myb_DNA-binding PF00249.29 001315575.1_06922001_1 - 1.9e-33 114.2 0.5 7e-17 61.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001315575.1_06922001_1 - 1.6e-19 69.8 0.5 3.2e-12 46.4 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001315575.1_06922001_1 - 0.0032 17.3 0.0 0.073 13.0 0.0 2.7 3 0 0 3 3 3 1 SLIDE Myb_DNA-bind_2 PF08914.9 001315575.1_06922001_1 - 0.03 14.4 0.0 0.82 9.8 0.0 2.6 2 1 0 2 2 2 0 Rap1 Myb domain FA_desaturase PF00487.22 001316024.1_06923001_1 - 1.8e-31 109.8 28.9 2.5e-31 109.3 28.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.6 001316024.1_06923001_1 - 2.7e-22 79.2 0.1 5e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Acyl-ACP_TE PF01643.15 001315887.1_06923001_1 - 6.2e-80 267.9 0.0 2.2e-79 266.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-ACP thioesterase Acyl-thio_N PF12590.6 001315887.1_06923001_1 - 7.1e-52 175.3 1.8 1.1e-51 174.6 1.8 1.3 1 0 0 1 1 1 1 Acyl-ATP thioesterase 4HBT_2 PF13279.4 001315887.1_06923001_1 - 3.5e-05 24.1 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 2 Thioesterase-like superfamily E1-E2_ATPase PF00122.18 001316133.1_06927001_1 - 2.8e-61 206.5 1.9 2.8e-61 206.5 1.9 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.24 001316133.1_06927001_1 - 4.1e-44 151.3 1.1 7.5e-44 150.4 1.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.24 001316133.1_06927001_1 - 9.3e-30 102.7 0.5 1.6e-12 47.6 0.0 3.8 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.10 001316133.1_06927001_1 - 7.9e-06 25.7 1.4 2e-05 24.3 1.4 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PASTA PF03793.17 001316133.1_06927001_1 - 0.28 10.9 1.5 3.1 7.6 0.0 3.0 3 0 0 3 3 3 0 PASTA domain Fer2_BFD PF04324.13 001316133.1_06927001_1 - 0.69 10.2 5.2 1.9 8.7 0.3 3.7 3 1 0 3 3 3 0 BFD-like [2Fe-2S] binding domain Pkinase PF00069.23 001316099.1_06923001_1 - 3.8e-69 232.9 0.0 5.2e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316099.1_06923001_1 - 1.2e-35 123.0 0.0 2.1e-35 122.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase NAF PF03822.12 001316099.1_06923001_1 - 1.3e-17 63.6 0.3 2.5e-17 62.7 0.3 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001316099.1_06923001_1 - 2e-07 30.5 0.0 3.8e-06 26.3 0.0 2.4 1 1 0 2 2 2 1 Kinase-like KA1 PF02149.17 001316099.1_06923001_1 - 9.4e-06 25.2 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 FliX PF10768.7 001316099.1_06923001_1 - 0.03 14.7 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Class II flagellar assembly regulator Kdo PF06293.12 001316099.1_06923001_1 - 0.047 12.9 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001316099.1_06923001_1 - 0.061 13.1 0.0 1 9.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family EF-hand_1 PF00036.30 001315757.1_06922001_1 - 1.3e-16 58.7 13.2 0.00017 20.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001315757.1_06922001_1 - 1.8e-13 49.1 9.9 0.004 16.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001315757.1_06922001_1 - 1.3e-12 46.5 11.2 5.2e-05 22.5 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001315757.1_06922001_1 - 1.2e-10 41.6 9.4 3.4e-07 30.5 1.8 3.1 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.4 001315757.1_06922001_1 - 2.1e-05 24.1 10.0 0.0009 18.8 0.4 3.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.5 001315757.1_06922001_1 - 7.9e-05 22.4 1.3 0.012 15.4 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001315757.1_06922001_1 - 0.0033 17.6 0.8 4.1 7.7 0.3 3.1 3 1 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.7 001315757.1_06922001_1 - 0.029 14.6 0.6 0.13 12.5 0.5 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DinI PF06183.11 001315757.1_06922001_1 - 0.15 12.3 0.2 1.9 8.8 0.1 2.2 2 0 0 2 2 2 0 DinI-like family 2OG-FeII_Oxy PF03171.18 001315692.1_06922001_1 - 4.5e-24 84.7 0.0 7.8e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001315692.1_06922001_1 - 1.1e-15 58.2 0.0 1.9e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WRKY PF03106.13 001316232.1_06923001_1 - 3.9e-52 174.3 15.3 4e-26 91.0 2.7 2.6 2 0 0 2 2 2 2 WRKY DNA -binding domain Cytokin-bind PF09265.8 001316206.1_06924001_2 - 5.6e-105 350.6 0.1 6.9e-105 350.3 0.1 1.1 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 001316206.1_06924001_2 - 1.3e-23 83.1 0.9 2.2e-23 82.4 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain Peptidase_M19 PF01244.19 001316206.1_06924001_2 - 0.058 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) WRKY PF03106.13 001315886.1_06923001_2 - 4.5e-25 87.6 3.7 4.5e-25 87.6 3.7 1.9 2 0 0 2 2 2 1 WRKY DNA -binding domain DUF4763 PF15960.3 001315886.1_06923001_2 - 0.83 8.8 5.1 0.9 8.7 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) p450 PF00067.20 001316088.1_06924001_1 - 7e-108 361.2 0.3 8.6e-108 360.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1232 PF06803.10 001316088.1_06924001_1 - 0.037 13.7 1.4 0.037 13.7 1.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1232) PCP_red PF08369.8 001316088.1_06924001_1 - 0.28 11.3 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit PMSR PF01625.19 001315845.1_06923001_1 - 5.6e-61 205.1 0.9 8e-61 204.6 0.9 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase IPPT PF01715.15 001315690.1_06924001_1 - 1.8e-62 211.0 0.0 2.3e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.14 001315690.1_06924001_1 - 6.8e-08 32.0 0.0 1.6e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.4 001315690.1_06924001_1 - 0.00017 21.7 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.4 001315690.1_06924001_1 - 0.00074 19.7 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001315690.1_06924001_1 - 0.0011 19.3 0.0 0.008 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.4 001315690.1_06924001_1 - 0.0014 18.9 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.10 001315690.1_06924001_1 - 0.0014 17.8 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin PF02224.16 001315690.1_06924001_1 - 0.0049 16.5 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.20 001315690.1_06924001_1 - 0.0086 16.3 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Hpr_kinase_C PF07475.10 001315690.1_06924001_1 - 0.0095 15.3 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain ResIII PF04851.13 001315690.1_06924001_1 - 0.036 13.9 0.0 0.094 12.6 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PPV_E1_C PF00519.15 001315690.1_06924001_1 - 0.044 12.5 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase IstB_IS21 PF01695.15 001315690.1_06924001_1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.25 001315690.1_06924001_1 - 0.071 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.14 001315690.1_06924001_1 - 0.085 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SSE PF00437.18 001315690.1_06924001_1 - 0.095 11.6 0.3 0.17 10.8 0.0 1.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.7 001315690.1_06924001_1 - 0.098 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.12 001315690.1_06924001_1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.16 001315690.1_06924001_1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.4 001315690.1_06924001_1 - 0.12 12.3 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.4 001315690.1_06924001_1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.11 001315690.1_06924001_1 - 0.24 10.2 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus NAM PF02365.13 001316108.1_06923001_1 - 2e-23 82.9 1.5 2.1e-23 82.8 0.2 1.7 2 0 0 2 2 2 1 No apical meristem (NAM) protein Glyco_hydro_32N PF00251.18 001315702.1_06924001_1 - 1.4e-106 356.4 9.6 1.8e-106 356.0 9.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.10 001315702.1_06924001_1 - 8.8e-14 51.9 0.0 2.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal NAM PF02365.13 001315627.1_06923001_2 - 3.7e-26 91.7 0.2 6.2e-26 90.9 0.2 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein Glyco_hydro_28 PF00295.15 001315989.1_06924001_1 - 1.4e-103 346.2 26.5 1.9e-103 345.9 26.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.5 001315989.1_06924001_1 - 1.4e-09 38.0 10.5 1.4e-09 38.0 10.5 3.2 1 1 1 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.4 001315989.1_06924001_1 - 2.3e-05 24.2 40.8 0.00044 20.0 12.1 2.5 1 1 2 3 3 3 2 Right handed beta helix region End_N_terminal PF12218.6 001315989.1_06924001_1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Pkinase PF00069.23 001316002.1_06924001_1 - 4.5e-52 176.9 0.1 8e-52 176.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316002.1_06924001_1 - 1.7e-37 129.0 0.1 2.8e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RRF PF01765.17 001316002.1_06924001_1 - 0.024 14.5 3.4 0.047 13.5 3.4 1.5 1 0 0 1 1 1 0 Ribosome recycling factor PBC PF03792.11 001316002.1_06924001_1 - 0.69 9.5 10.9 0.61 9.7 3.8 2.3 1 1 1 2 2 2 0 PBC domain TPR_1 PF00515.26 001316243.1_06925001_1 - 3.1e-23 80.5 0.1 6.8e-08 31.9 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.15 001316243.1_06925001_1 - 2.9e-20 70.5 3.0 6e-06 25.8 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.4 001316243.1_06925001_1 - 7.7e-20 70.2 6.3 6.1e-07 28.9 0.6 6.3 5 1 1 6 6 6 4 TPR repeat TPR_17 PF13431.4 001316243.1_06925001_1 - 2.1e-17 62.0 8.0 0.00043 20.3 0.2 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.4 001316243.1_06925001_1 - 3.9e-16 59.3 4.0 1.1e-05 25.9 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.4 001316243.1_06925001_1 - 1.2e-15 56.1 0.1 0.00062 19.7 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.4 001316243.1_06925001_1 - 2e-14 52.9 8.3 0.0048 17.5 0.0 7.0 4 2 4 8 8 6 5 Tetratricopeptide repeat TPR_19 PF14559.4 001316243.1_06925001_1 - 1.5e-12 47.7 10.0 0.0012 19.2 0.0 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.4 001316243.1_06925001_1 - 1.1e-08 34.9 1.4 0.0093 16.0 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.4 001316243.1_06925001_1 - 2.3e-08 33.4 3.6 0.008 16.0 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.4 001316243.1_06925001_1 - 7.2e-07 29.3 2.1 0.0071 16.5 0.1 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.4 001316243.1_06925001_1 - 0.013 15.7 2.1 0.85 9.9 0.1 3.5 2 2 1 4 4 4 0 Tetratricopeptide repeat Metallophos_2 PF12850.5 001316243.1_06925001_1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TPR_6 PF13174.4 001316243.1_06925001_1 - 0.18 12.4 3.7 1.2e+02 3.5 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.23 001315731.1_06923001_1 - 3.6e-74 249.3 0.0 5e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315731.1_06923001_1 - 3.5e-32 111.6 0.0 5.1e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001315731.1_06923001_1 - 7.5e-05 22.0 0.2 0.00011 21.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001315731.1_06923001_1 - 0.00061 19.1 0.0 0.0024 17.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001315731.1_06923001_1 - 0.082 12.7 0.3 0.79 9.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_14 PF01373.15 001316018.1_06924001_3 - 6.5e-127 423.7 0.0 7.7e-127 423.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.17 001316018.1_06924001_3 - 0.041 13.4 1.3 0.048 13.1 0.1 1.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.13 001316018.1_06924001_3 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase ANF_receptor PF01094.26 001315733.1_06927001_2 - 7.3e-81 271.9 0.0 1.1e-80 271.3 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001315733.1_06927001_2 - 1.5e-37 128.6 0.7 2.6e-37 127.8 0.7 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.18 001315733.1_06927001_2 - 4.3e-19 68.7 0.0 7.9e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.4 001315733.1_06927001_2 - 9.5e-15 55.0 0.0 1.6e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Lig_chan-Glu_bd PF10613.7 001315733.1_06927001_2 - 2.8e-06 27.4 0.0 7.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site TspO_MBR PF03073.13 001315733.1_06927001_2 - 0.2 11.5 6.2 0.7 9.8 6.2 1.9 1 0 0 1 1 1 0 TspO/MBR family Gp_dh_C PF02800.18 001315771.1_06923001_2 - 6.3e-72 240.2 0.0 9e-72 239.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001315771.1_06923001_2 - 5.3e-32 110.0 0.2 1.5e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001315771.1_06923001_2 - 0.00019 21.4 0.1 0.00075 19.5 0.0 2.1 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.17 001315771.1_06923001_2 - 0.022 14.0 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WRKY PF03106.13 001315783.1_06922001_3 - 2.6e-23 82.0 6.1 4.2e-23 81.3 2.0 2.5 2 0 0 2 2 2 1 WRKY DNA -binding domain FAR1 PF03101.13 001315783.1_06922001_3 - 0.86 10.2 6.3 0.14 12.7 2.0 2.0 2 1 0 2 2 2 0 FAR1 DNA-binding domain Pkinase_Tyr PF07714.15 001316149.1_06926001_1 - 1.9e-43 148.5 0.0 3.7e-43 147.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001316149.1_06926001_1 - 5e-42 144.0 0.0 7.3e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.5 001316149.1_06926001_1 - 1.1e-35 120.8 58.7 1.6e-07 31.4 0.7 11.5 7 3 5 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001316149.1_06926001_1 - 3.7e-32 109.7 56.1 9.7e-07 28.3 0.9 9.4 2 2 9 11 11 11 11 Leucine rich repeat LRR_1 PF00560.31 001316149.1_06926001_1 - 5.4e-14 50.3 44.1 0.96 10.0 0.1 15.9 16 3 1 17 17 17 5 Leucine Rich Repeat LRRNT_2 PF08263.10 001316149.1_06926001_1 - 4.3e-08 33.2 0.6 1e-07 32.0 0.6 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.4 001316149.1_06926001_1 - 1.4e-07 30.9 39.2 0.079 12.9 0.2 10.8 10 0 0 10 10 10 5 Leucine Rich repeat APH PF01636.21 001316149.1_06926001_1 - 0.038 13.8 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.23 001315729.1_06924001_1 - 1e-48 165.8 0.0 1.6e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315729.1_06924001_1 - 7.5e-33 113.8 0.0 1.4e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MIP PF00230.18 001316106.1_06922001_1 - 4.6e-85 284.8 11.5 5.2e-85 284.6 11.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Metallophos PF00149.26 001316070.1_06923001_2 - 1.5e-16 61.4 1.0 1.9e-16 61.0 1.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SQS_PSY PF00494.17 001315554.1_06924001_1 - 1.2e-74 251.0 1.4 1.2e-74 251.0 1.4 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase Pkinase PF00069.23 001315949.1_06923001_1 - 4.2e-64 216.3 0.0 5.7e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315949.1_06923001_1 - 1.5e-31 109.5 0.0 2.3e-31 108.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001315949.1_06923001_1 - 4.6e-05 22.7 0.5 4.6e-05 22.7 0.5 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.29 001315555.1_06922001_1 - 5.8e-32 109.5 5.1 1.5e-15 56.9 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001315555.1_06922001_1 - 8.2e-20 70.7 2.7 5e-13 49.0 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain FAM199X PF15814.3 001315555.1_06922001_1 - 0.004 16.1 0.2 0.0079 15.2 0.2 1.5 1 0 0 1 1 1 1 Protein family FAM199X Myb_DNA-bind_7 PF15963.3 001315555.1_06922001_1 - 0.0065 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Pkinase PF00069.23 001316289.1_06923001_1 - 1.3e-74 250.8 0.0 1.7e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316289.1_06923001_1 - 1.6e-32 112.7 0.0 2.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001316289.1_06923001_1 - 5.8e-05 22.4 0.2 8.6e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001316289.1_06923001_1 - 0.00027 20.2 0.0 0.0015 17.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001316289.1_06923001_1 - 0.047 13.5 0.3 0.56 9.9 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.20 001316289.1_06923001_1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Methyltransf_11 PF08241.10 001316019.1_06923001_1 - 7.1e-20 71.3 0.0 1.2e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001316019.1_06923001_1 - 4e-17 62.6 0.0 6.9e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 001316019.1_06923001_1 - 1.9e-14 53.8 0.0 2.7e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001316019.1_06923001_1 - 2.5e-14 53.2 0.0 3.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.18 001316019.1_06923001_1 - 3.4e-11 42.8 0.0 5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.16 001316019.1_06923001_1 - 1.1e-08 34.6 0.0 1.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.10 001316019.1_06923001_1 - 5.3e-08 33.4 0.0 8.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.16 001316019.1_06923001_1 - 0.0033 16.5 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.4 001316019.1_06923001_1 - 0.036 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.14 001316019.1_06923001_1 - 0.042 12.3 0.0 0.054 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.17 001316019.1_06923001_1 - 0.05 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.12 001316019.1_06923001_1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain NAS PF03059.14 001316019.1_06923001_1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein BCDHK_Adom3 PF10436.7 001315616.1_06923001_1 - 1.4e-51 174.4 0.0 1.9e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.24 001315616.1_06923001_1 - 1e-13 51.7 0.0 1.8e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001315616.1_06923001_1 - 0.0004 20.1 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase bZIP_1 PF00170.19 001316130.1_06923001_1 - 1.6e-14 53.6 16.9 8e-14 51.4 10.2 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.13 001316130.1_06923001_1 - 6.7e-10 38.8 16.7 9e-10 38.4 15.8 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.15 001316130.1_06923001_1 - 0.00026 21.3 10.0 0.001 19.4 9.4 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor Atg14 PF10186.7 001316130.1_06923001_1 - 0.32 9.9 3.1 0.47 9.4 3.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Annexin PF00191.18 001316173.1_06922001_1 - 1.2e-70 233.3 12.2 8.8e-21 73.6 0.1 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.3 001316173.1_06922001_1 - 0.036 13.8 0.0 23 4.8 0.0 3.4 3 0 0 3 3 3 0 Myb DNA-binding like Gluconate_2-dh3 PF13618.4 001316173.1_06922001_1 - 0.13 12.4 0.4 5.3 7.2 0.1 2.2 1 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Pkinase PF00069.23 001315893.1_06923001_2 - 4.7e-70 235.8 0.0 5.8e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315893.1_06923001_2 - 4.6e-37 127.6 0.0 6.1e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001315893.1_06923001_2 - 5.7e-05 22.4 0.0 0.0013 18.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001315893.1_06923001_2 - 0.0024 17.7 0.0 0.035 13.9 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.20 001315893.1_06923001_2 - 0.0089 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.9 001315893.1_06923001_2 - 0.011 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.12 001315893.1_06923001_2 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.18 001315893.1_06923001_2 - 0.018 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase WRKY PF03106.13 001315864.1_06924001_1 - 1.9e-27 95.2 1.7 4.4e-27 94.1 1.7 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain Mto2_bdg PF12808.5 001315864.1_06924001_1 - 0.088 13.0 0.3 0.19 11.9 0.3 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Sulfate_transp PF00916.18 001316188.1_06925001_2 - 8.8e-134 445.9 20.7 1.1e-133 445.5 20.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001316188.1_06925001_2 - 1.9e-31 108.0 0.0 3.7e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.4 001316188.1_06925001_2 - 0.038 14.2 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 STAS domain WD40 PF00400.30 001315859.1_06925001_1 - 9.5e-22 76.8 8.9 0.00053 20.6 0.0 7.8 8 0 0 8 8 7 4 WD domain, G-beta repeat zf-C3HC4_2 PF13923.4 001315859.1_06925001_1 - 4e-11 42.4 14.4 9.2e-11 41.3 14.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001315859.1_06925001_1 - 2.1e-08 33.8 14.9 5e-08 32.6 14.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001315859.1_06925001_1 - 4.7e-08 32.6 11.7 1.3e-07 31.2 11.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WD40_like PF17005.3 001315859.1_06925001_1 - 1.8e-07 30.7 0.1 1.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain zf-RING_2 PF13639.4 001315859.1_06925001_1 - 1.6e-06 28.1 13.3 5.5e-06 26.4 13.3 2.0 1 0 0 1 1 1 1 Ring finger domain ANAPC4_WD40 PF12894.5 001315859.1_06925001_1 - 6.9e-06 26.1 0.4 7 6.9 0.0 4.6 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.4 001315859.1_06925001_1 - 0.00011 21.9 13.2 0.00011 21.9 13.2 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001315859.1_06925001_1 - 0.00044 20.1 13.1 0.00044 20.1 13.1 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001315859.1_06925001_1 - 0.0017 18.3 12.5 0.0017 18.3 12.5 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING U-box PF04564.13 001315859.1_06925001_1 - 0.0023 17.9 0.0 0.0074 16.3 0.0 1.8 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.4 001315859.1_06925001_1 - 0.0038 16.9 11.9 0.011 15.4 11.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 eIF2A PF08662.9 001315859.1_06925001_1 - 0.027 14.2 0.1 2.7 7.7 0.0 3.0 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF1664 PF07889.10 001315859.1_06925001_1 - 0.055 13.3 1.2 0.14 12.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-RING_10 PF16685.3 001315859.1_06925001_1 - 0.09 12.8 7.8 0.29 11.2 7.8 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.4 001315859.1_06925001_1 - 0.13 12.0 3.7 0.34 10.7 3.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_p24 PF05073.10 001315859.1_06925001_1 - 0.19 11.3 2.3 0.87 9.2 0.2 2.6 3 0 0 3 3 3 0 Baculovirus P24 capsid protein zf-rbx1 PF12678.5 001315859.1_06925001_1 - 0.42 10.8 16.0 0.24 11.6 12.0 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-Nse PF11789.6 001315859.1_06925001_1 - 2.2 8.0 11.0 1.9 8.3 7.3 2.6 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.5 001315859.1_06925001_1 - 6 6.9 9.5 7.4 6.6 5.5 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger WRKY PF03106.13 001316258.1_06924001_2 - 2.1e-27 95.1 1.7 4.3e-27 94.1 1.7 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain Mto2_bdg PF12808.5 001316258.1_06924001_2 - 0.026 14.7 0.5 0.049 13.8 0.5 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FlaC_arch PF05377.9 001316258.1_06924001_2 - 0.13 12.5 0.9 0.47 10.8 0.9 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) APG6 PF04111.10 001316258.1_06924001_2 - 0.3 10.3 3.3 0.47 9.6 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.7 001316258.1_06924001_2 - 1.8 8.5 9.8 5.2 7.0 9.8 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NAM PF02365.13 001315964.1_06923001_1 - 8.7e-26 90.5 0.4 1.3e-25 89.9 0.4 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein CTP_transf_like PF01467.24 001315940.1_06923001_1 - 9.2e-33 113.3 0.0 1.8e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Rhodanese PF00581.18 001315650.1_06923001_1 - 9.5e-30 103.1 0.0 5.9e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Pkinase PF00069.23 001316116.1_06923001_1 - 4e-71 239.3 0.0 4.7e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316116.1_06923001_1 - 8.1e-32 110.4 0.0 1.1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001316116.1_06923001_1 - 7.6e-07 28.5 0.8 1.1e-06 28.0 0.8 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001316116.1_06923001_1 - 0.0073 15.5 0.0 0.025 13.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.21 001316116.1_06923001_1 - 0.012 15.5 0.3 0.028 14.2 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sod_Fe_C PF02777.16 001315781.1_06923001_1 - 1.2e-34 118.4 0.4 2.2e-34 117.5 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.20 001315781.1_06923001_1 - 3.5e-21 75.3 0.4 9.1e-21 74.0 0.4 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pro_CA PF00484.17 001315587.1_06923001_1 - 4.3e-42 143.9 0.0 1.1e-41 142.6 0.0 1.6 2 0 0 2 2 2 1 Carbonic anhydrase Miga PF10265.7 001315587.1_06923001_1 - 0.21 10.4 0.2 0.28 10.0 0.2 1.1 1 0 0 1 1 1 0 Mitoguardin Pkinase PF00069.23 001315810.1_06925001_3 - 9.2e-70 234.9 0.0 1.3e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315810.1_06925001_3 - 1.6e-53 181.5 0.0 2.2e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001315810.1_06925001_3 - 6.9e-08 32.0 0.0 6.6e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.12 001315810.1_06925001_3 - 0.00098 18.4 0.2 0.0019 17.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family NAM PF02365.13 001316101.1_06922001_1 - 4.1e-26 91.5 0.3 8e-26 90.6 0.3 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein AMP-binding PF00501.26 001315918.1_06925001_1 - 2.7e-103 345.7 0.0 3.3e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001315918.1_06925001_1 - 4e-05 24.4 0.0 0.0001 23.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lipase_GDSL PF00657.20 001316050.1_06923001_2 - 7e-24 84.8 0.0 8.6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WRKY PF03106.13 001315924.1_06923001_3 - 1.3e-47 159.8 12.0 1e-24 86.5 2.2 2.3 2 0 0 2 2 2 2 WRKY DNA -binding domain Sod_Fe_N PF00081.20 001315655.1_06922001_1 - 1.3e-35 121.6 1.2 2.1e-35 120.9 1.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.16 001315655.1_06922001_1 - 7.8e-35 119.0 0.2 3e-34 117.1 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Kelch_1 PF01344.23 001316057.1_06923001_2 - 1.8e-43 145.8 2.0 3.7e-10 39.1 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.4 001316057.1_06923001_2 - 5.1e-31 105.8 8.0 4.9e-09 36.0 0.0 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_4 PF13418.4 001316057.1_06923001_2 - 5.8e-30 102.9 15.3 1.3e-08 34.5 0.1 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.13 001316057.1_06923001_2 - 1.7e-26 91.0 7.9 9.8e-07 28.4 0.0 5.6 5 1 0 5 5 5 5 Kelch motif Kelch_3 PF13415.4 001316057.1_06923001_2 - 3.9e-24 84.2 11.6 5.4e-09 36.0 0.0 7.4 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.4 001316057.1_06923001_2 - 1.1e-21 76.2 9.2 4e-05 23.4 0.1 6.1 6 0 0 6 6 6 4 Kelch motif DUF1668 PF07893.11 001316057.1_06923001_2 - 0.0035 16.6 4.3 3 7.0 0.0 3.8 2 2 2 4 4 4 1 Protein of unknown function (DUF1668) PQQ_3 PF13570.4 001316057.1_06923001_2 - 0.1 13.0 3.8 10 6.6 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain RAG2 PF03089.12 001316057.1_06923001_2 - 0.11 11.3 0.1 1.2 7.9 0.0 2.6 4 0 0 4 4 4 0 Recombination activating protein 2 Lipase_GDSL PF00657.20 001315667.1_06923001_1 - 1.6e-25 90.1 0.1 2e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NAM PF02365.13 001316156.1_06923001_1 - 1.1e-25 90.2 0.1 1.8e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein WRC PF08879.8 001315881.1_06923001_1 - 2e-21 75.4 8.4 3.3e-21 74.6 8.4 1.4 1 0 0 1 1 1 1 WRC QLQ PF08880.9 001315881.1_06923001_1 - 2.2e-13 49.6 0.9 3.8e-13 48.8 0.9 1.4 1 0 0 1 1 1 1 QLQ zf-C3Hc3H PF13891.4 001315881.1_06923001_1 - 0.095 12.9 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 Potential DNA-binding domain NAM PF02365.13 001315958.1_06922001_1 - 5.3e-30 104.0 0.6 8.6e-30 103.3 0.6 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein Gln-synt_C PF00120.22 001315808.1_06923001_1 - 2.2e-16 59.7 0.0 1e-14 54.2 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001315808.1_06923001_1 - 3.7e-10 39.3 0.0 6e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain BURP PF03181.13 001315546.1_06923001_3 - 1.6e-83 279.4 0.5 2e-83 279.1 0.5 1.1 1 0 0 1 1 1 1 BURP domain Jacalin PF01419.15 001316044.1_06925001_3 - 2.5e-147 483.8 19.4 2.8e-47 159.9 0.5 4.1 4 0 0 4 4 4 4 Jacalin-like lectin domain RGS PF00615.17 001315965.1_06923001_1 - 5.1e-12 46.0 0.1 7.7e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3474 PF11960.6 001315836.1_06923001_2 - 1.1e-49 167.7 0.5 1.9e-49 167.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.22 001315836.1_06923001_2 - 1.9e-31 109.7 27.4 2.9e-31 109.1 27.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Hum_adeno_E3A PF05393.9 001315836.1_06923001_2 - 0.37 10.7 4.2 3.6 7.5 0.6 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Lycopene_cycl PF05834.10 001316134.1_06924001_3 - 1.4e-150 501.5 0.0 1.6e-150 501.3 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.12 001316134.1_06924001_3 - 2.7e-07 30.0 3.5 8.2e-07 28.4 1.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001316134.1_06924001_3 - 7.4e-06 25.7 1.3 0.053 13.0 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.4 001316134.1_06924001_3 - 0.00025 20.9 0.5 0.81 9.6 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.5 001316134.1_06924001_3 - 0.00028 20.2 0.8 0.0015 17.8 0.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.12 001316134.1_06924001_3 - 0.00039 19.3 0.4 0.041 12.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.4 001316134.1_06924001_3 - 0.00057 19.1 2.0 0.033 13.3 0.4 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001316134.1_06924001_3 - 0.0014 17.9 0.1 0.0021 17.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.15 001316134.1_06924001_3 - 0.0022 17.2 3.6 0.04 13.0 3.6 2.1 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.4 001316134.1_06924001_3 - 0.0026 17.8 0.1 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.12 001316134.1_06924001_3 - 0.0033 16.0 1.3 0.0058 15.2 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.22 001316134.1_06924001_3 - 0.005 15.8 0.7 0.01 14.8 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.25 001316134.1_06924001_3 - 0.0065 16.9 0.4 0.48 10.9 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001316134.1_06924001_3 - 0.038 13.0 4.0 1 8.3 4.0 2.1 1 1 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.4 001316134.1_06924001_3 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain PLD_C PF12357.6 001315873.1_06925001_1 - 4.1e-29 100.1 0.0 7.6e-29 99.3 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.20 001315873.1_06925001_1 - 1.5e-19 69.1 0.8 4.9e-09 35.9 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif C2 PF00168.28 001315873.1_06925001_1 - 2.2e-13 50.2 0.0 5.4e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain PLDc_2 PF13091.4 001315873.1_06925001_1 - 9.6e-11 41.6 0.1 1.3e-07 31.4 0.1 3.5 2 2 0 2 2 2 2 PLD-like domain Cyclin_N PF00134.21 001315875.1_06924001_1 - 3.2e-38 130.3 1.5 4.8e-38 129.7 0.5 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001315875.1_06924001_1 - 7.1e-34 116.3 0.7 1.4e-33 115.3 0.7 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain CPSase_L_D2 PF02786.15 001316151.1_06924001_1 - 5.3e-81 271.0 0.0 8.2e-81 270.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.20 001316151.1_06924001_1 - 2.1e-39 134.4 0.0 3.9e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.17 001316151.1_06924001_1 - 6e-39 132.3 0.0 1.8e-38 130.8 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.20 001316151.1_06924001_1 - 3.9e-10 39.4 0.0 9.2e-10 38.2 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.11 001316151.1_06924001_1 - 5.6e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.4 001316151.1_06924001_1 - 3e-06 26.0 0.0 0.00067 18.3 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.9 001316151.1_06924001_1 - 0.00063 19.3 0.0 0.002 17.6 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.4 001316151.1_06924001_1 - 0.028 13.7 0.0 0.12 11.7 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain p450 PF00067.20 001316183.1_06924001_3 - 3.5e-98 329.2 0.0 4.5e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kelch_3 PF13415.4 001315816.1_06925001_1 - 2e-36 123.4 11.6 3.9e-11 42.8 0.0 6.9 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.4 001315816.1_06925001_1 - 8e-33 111.5 4.6 6.8e-07 29.2 0.0 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.4 001315816.1_06925001_1 - 1.9e-29 101.0 1.4 7.5e-07 28.9 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.4 001315816.1_06925001_1 - 2.7e-29 100.7 13.7 2.2e-08 33.8 0.0 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.23 001315816.1_06925001_1 - 3.4e-28 96.8 3.8 3.1e-08 32.9 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.13 001315816.1_06925001_1 - 9.2e-27 91.8 7.7 7.3e-08 32.0 0.0 6.4 6 0 0 6 6 6 4 Kelch motif ACBP PF00887.17 001315816.1_06925001_1 - 5.9e-19 67.9 0.0 1.6e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein CALCOCO1 PF07888.9 001315816.1_06925001_1 - 0.0001 20.9 10.5 0.00015 20.4 10.5 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.12 001315816.1_06925001_1 - 0.086 12.5 16.7 0.13 11.9 16.7 1.2 1 0 0 1 1 1 0 IncA protein GAS PF13851.4 001315816.1_06925001_1 - 0.48 9.6 14.6 0.97 8.6 14.6 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_23 PF13476.4 001315816.1_06925001_1 - 1.7 9.0 7.0 2.9 8.2 7.0 1.3 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.12 001315816.1_06925001_1 - 2.5 7.8 9.8 5.1 6.7 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.6 001315816.1_06925001_1 - 7.8 6.4 19.0 20 5.1 16.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.23 001316180.1_06923001_1 - 2.4e-71 240.1 0.0 2.9e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316180.1_06923001_1 - 1.9e-32 112.5 0.0 2.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001316180.1_06923001_1 - 3.6e-07 29.6 0.7 5.6e-07 29.0 0.7 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001316180.1_06923001_1 - 0.0021 17.3 0.0 0.0045 16.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.21 001316180.1_06923001_1 - 0.0071 16.2 0.3 0.052 13.3 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family dsrm PF00035.24 001315851.1_06922001_1 - 1.3e-31 108.9 0.7 3.2e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.5 001315851.1_06922001_1 - 8.3e-07 29.0 3.3 0.035 14.2 0.0 3.3 2 1 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 PKI PF02827.14 001315851.1_06922001_2 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Amino_oxidase PF01593.22 001315877.1_06924001_1 - 1.5e-64 218.8 0.0 1.7e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001315877.1_06924001_1 - 3.1e-14 52.8 0.2 6e-14 51.9 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001315877.1_06924001_1 - 3.6e-06 26.7 0.2 6.8e-05 22.5 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 001315877.1_06924001_1 - 0.00012 21.3 0.1 0.00025 20.3 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001315877.1_06924001_1 - 0.00033 19.3 0.5 0.00056 18.6 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein MCRA PF06100.9 001315877.1_06924001_1 - 0.0012 17.6 0.0 0.032 12.9 0.0 2.1 2 0 0 2 2 2 1 MCRA family FAD_binding_2 PF00890.22 001315877.1_06924001_1 - 0.002 17.1 0.3 0.0032 16.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.17 001315877.1_06924001_1 - 0.0022 17.2 0.1 0.0049 16.1 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.19 001315877.1_06924001_1 - 0.0057 15.8 0.1 0.052 12.7 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.5 001315877.1_06924001_1 - 0.0064 15.8 0.0 0.0093 15.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.16 001315877.1_06924001_1 - 0.018 14.8 0.4 0.036 13.8 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.20 001315877.1_06924001_1 - 0.036 13.0 0.1 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.4 001315877.1_06924001_1 - 0.045 13.6 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.4 001315877.1_06924001_1 - 0.074 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pro_CA PF00484.17 001315953.1_06922001_1 - 2.4e-41 141.5 0.0 6.8e-41 140.0 0.0 1.6 2 0 0 2 2 2 1 Carbonic anhydrase PHM7_cyt PF14703.4 001315953.1_06922001_1 - 0.06 13.5 0.2 0.097 12.8 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Cauli_DNA-bind PF03310.11 001315953.1_06922001_1 - 0.071 13.0 0.2 0.44 10.5 0.1 2.1 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Cpn60_TCP1 PF00118.22 001316161.1_06924001_3 - 1.3e-90 304.3 13.7 2e-90 303.7 13.7 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Oleosin PF01277.15 001315767.1_06922001_2 - 7.1e-39 131.9 3.1 1.3e-38 131.1 3.1 1.4 1 0 0 1 1 1 1 Oleosin DUF3487 PF11990.6 001315767.1_06922001_2 - 6.7 6.5 6.9 13 5.6 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) MBOAT PF03062.17 001315803.1_06924001_1 - 2.4e-26 92.8 22.2 2.4e-26 92.8 22.2 1.6 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.4 001315803.1_06924001_1 - 8.7e-05 22.6 2.4 0.00021 21.4 2.4 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family NAD_Gly3P_dh_C PF07479.12 001316073.1_06923001_3 - 1.5e-24 86.7 0.0 2.7e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.21 001316073.1_06923001_3 - 1.2e-14 54.4 0.1 2.6e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.14 001316073.1_06923001_3 - 0.0085 15.6 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.4 001316073.1_06923001_3 - 0.15 12.2 0.6 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAM PF02365.13 001316047.1_06922001_3 - 6.7e-27 94.0 0.3 1.1e-26 93.4 0.3 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein PP2C PF00481.19 001315830.1_06923001_1 - 1.8e-61 207.9 0.0 3.7e-61 206.9 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001315830.1_06923001_1 - 0.031 13.8 0.0 0.7 9.4 0.0 2.4 1 1 1 2 2 2 0 Protein phosphatase 2C START PF01852.17 001315921.1_06926001_2 - 1.4e-41 142.1 0.2 1e-40 139.3 0.0 2.3 2 1 0 2 2 2 1 START domain Homeobox PF00046.27 001315921.1_06926001_2 - 1.3e-17 63.3 3.5 4e-17 61.6 3.5 1.9 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001315921.1_06926001_2 - 0.00034 20.3 0.3 0.00098 18.8 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain SQS_PSY PF00494.17 001316292.1_06924001_2 - 3.4e-74 249.5 1.8 4.1e-74 249.3 1.8 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase peroxidase PF00141.21 001316103.1_06923001_1 - 1.5e-47 162.1 0.0 2.4e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase WRKY PF03106.13 001315743.1_06922001_2 - 1.5e-26 92.4 0.2 1.5e-26 92.4 0.2 1.8 2 0 0 2 2 2 1 WRKY DNA -binding domain Plant_zn_clust PF10533.7 001315743.1_06922001_2 - 1.7e-16 59.8 8.7 3.4e-16 58.8 8.7 1.6 1 0 0 1 1 1 1 Plant zinc cluster domain Pkinase PF00069.23 001316241.1_06924001_1 - 1.2e-75 254.2 0.0 1.6e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001316241.1_06924001_1 - 2e-31 105.0 10.4 4.7e-08 31.9 0.5 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001316241.1_06924001_1 - 3.1e-28 98.6 0.0 4.6e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001316241.1_06924001_1 - 2.9e-24 85.2 2.8 1.6e-12 47.5 2.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001316241.1_06924001_1 - 4.7e-24 82.1 5.7 3.7e-07 29.4 0.4 5.0 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.4 001316241.1_06924001_1 - 4.9e-20 70.9 10.9 1.6e-09 37.2 0.5 4.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.4 001316241.1_06924001_1 - 3.8e-18 64.0 7.1 0.00017 20.8 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.5 001316241.1_06924001_1 - 6.4e-07 29.1 1.1 0.027 14.3 0.0 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.4 001316241.1_06924001_1 - 2.4e-06 27.0 0.0 0.0011 18.2 0.0 2.7 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.12 001316241.1_06924001_1 - 3.1e-06 26.6 0.0 6.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.4 001316241.1_06924001_1 - 0.0076 16.4 0.3 6.9 6.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain APH PF01636.21 001316241.1_06924001_1 - 0.042 13.6 0.0 0.16 11.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.20 001316241.1_06924001_1 - 0.047 13.2 0.1 0.14 11.6 0.1 1.8 1 0 0 1 1 1 0 RIO1 family NAM PF02365.13 001315962.1_06922001_1 - 6.8e-15 55.6 0.2 1.1e-14 54.9 0.2 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein YhfH PF14149.4 001315962.1_06922001_1 - 0.22 11.4 2.0 0.62 10.0 2.0 1.7 1 0 0 1 1 1 0 YhfH-like protein NAM PF02365.13 001315681.1_06922001_1 - 5.2e-27 94.4 0.6 9.5e-27 93.5 0.6 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein MatE PF01554.16 001315870.1_06924001_2 - 2.3e-52 176.8 43.7 6.5e-28 97.3 17.9 2.6 3 0 0 3 3 3 2 MatE DUF3382 PF11862.6 001315979.1_06923001_1 - 0.07 13.3 1.8 0.21 11.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Sina PF03145.14 001315979.1_06923001_3 - 1.9e-16 60.6 0.5 1.9e-16 60.6 0.5 1.6 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_3 PF13920.4 001315979.1_06923001_3 - 0.001 18.7 12.6 0.001 18.7 12.6 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001315979.1_06923001_3 - 0.059 13.2 14.2 0.21 11.5 14.2 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Myc_N PF01056.16 001315979.1_06923001_3 - 0.066 12.9 5.1 0.1 12.3 5.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region MscS_TM PF12794.5 001315979.1_06923001_3 - 0.15 10.7 0.9 0.23 10.2 0.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 zf-C3HC4_2 PF13923.4 001315979.1_06923001_3 - 0.61 9.8 16.6 0.44 10.3 14.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SDA1 PF05285.10 001315979.1_06923001_3 - 4.5 6.5 13.6 1.9 7.7 9.2 1.9 2 0 0 2 2 2 0 SDA1 zf-RING_UBOX PF13445.4 001315979.1_06923001_3 - 5.3 7.0 12.8 13 5.7 12.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Glyco_hydro_28 PF00295.15 001315946.1_06924001_1 - 3e-100 335.3 26.0 5.2e-100 334.5 26.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.5 001315946.1_06924001_1 - 1.9e-09 37.6 18.1 1.9e-07 31.1 13.8 3.9 1 1 1 2 2 2 1 Pectate lyase superfamily protein End_N_terminal PF12218.6 001315946.1_06924001_1 - 0.021 14.4 0.4 0.051 13.1 0.0 1.9 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Methyltransf_7 PF03492.13 001315983.1_06923001_2 - 1.8e-86 290.2 0.0 2.3e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase 2OG-FeII_Oxy PF03171.18 001315992.1_06922001_1 - 1.1e-25 89.9 0.0 2.2e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001315992.1_06922001_1 - 4e-14 53.3 0.0 7.2e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal adh_short_C2 PF13561.4 001316267.1_06923001_1 - 1.4e-53 181.8 1.8 2.7e-50 171.0 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001316267.1_06923001_1 - 2.8e-10 39.8 0.0 3e-08 33.2 0.0 2.5 3 0 0 3 3 3 2 short chain dehydrogenase Enoyl_reductase PF12241.6 001316267.1_06923001_1 - 0.0014 17.9 0.1 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region Pkinase PF00069.23 001316144.1_06923001_2 - 2e-69 233.8 0.0 2.7e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316144.1_06923001_2 - 4.7e-31 107.9 0.0 6.4e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_3_Rpc31 PF11705.6 001316144.1_06923001_2 - 0.0015 18.7 5.5 0.0024 18.0 5.5 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 APH PF01636.21 001316144.1_06923001_2 - 0.05 13.4 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001316144.1_06923001_2 - 0.097 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Astro_capsid_p PF12226.6 001316144.1_06923001_2 - 1.1 8.2 3.4 1.7 7.5 3.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.8 001316144.1_06923001_2 - 9 6.6 9.1 17 5.7 9.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Lipase_GDSL PF00657.20 001315763.1_06923001_2 - 1.1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amb_V_allergen PF03913.11 001315763.1_06923001_2 - 0.2 11.5 2.7 0.44 10.4 2.7 1.5 1 0 0 1 1 1 0 Amb V Allergen Lipase_GDSL PF00657.20 001315789.1_06923001_1 - 1.1e-07 31.9 0.0 1.7e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1273 PF06908.9 001315789.1_06923001_1 - 0.058 13.3 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) 14-3-3 PF00244.18 001316080.1_06923001_1 - 1.4e-103 345.0 6.2 1.8e-103 344.7 6.2 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF1620 PF07774.11 001316080.1_06923001_1 - 0.034 13.7 0.2 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1620) DUF837 PF05769.9 001316080.1_06923001_1 - 1.9 8.3 10.5 0.22 11.3 3.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF837) CHASE PF03924.11 001315852.1_06927001_1 - 7.3e-41 140.0 0.3 4.3e-40 137.5 0.4 2.0 2 0 0 2 2 2 1 CHASE domain HATPase_c PF02518.24 001315852.1_06927001_1 - 1e-31 109.6 0.2 9.8e-31 106.5 0.2 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.22 001315852.1_06927001_1 - 1.3e-22 80.0 0.0 1.8e-20 73.0 0.0 3.3 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.23 001315852.1_06927001_1 - 2.4e-19 69.0 0.3 1e-18 67.0 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain ELO PF01151.16 001315852.1_06927001_1 - 0.00091 18.7 1.0 0.0029 17.0 0.6 1.9 2 0 0 2 2 2 1 GNS1/SUR4 family Catalase PF00199.17 001316190.1_06923001_1 - 2.5e-171 569.9 0.0 2.8e-171 569.7 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.10 001316190.1_06923001_1 - 6e-16 58.3 0.0 1.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive HdeA PF06411.9 001316190.1_06923001_1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 HdeA/HdeB family FAD_binding_3 PF01494.17 001315888.1_06925001_1 - 8.7e-16 58.0 0.0 5.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FHA PF00498.24 001315888.1_06925001_1 - 1.2e-11 44.6 0.0 2.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain Pyr_redox_2 PF07992.12 001315888.1_06925001_1 - 5.4e-06 25.7 0.9 0.0028 16.8 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001315888.1_06925001_1 - 8.4e-05 22.6 0.5 8.4e-05 22.6 0.5 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.22 001315888.1_06925001_1 - 0.00027 20.0 0.6 0.00043 19.3 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.22 001315888.1_06925001_1 - 0.0042 16.6 1.8 0.059 12.9 0.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Yop-YscD_cpl PF16697.3 001315888.1_06925001_1 - 0.024 14.8 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain HI0933_like PF03486.12 001315888.1_06925001_1 - 0.065 11.8 0.2 0.14 10.7 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.5 001315888.1_06925001_1 - 0.07 12.3 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase N2227 PF07942.10 001315888.1_06925001_1 - 0.089 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein AlaDh_PNT_C PF01262.19 001315888.1_06925001_1 - 0.16 11.1 1.0 0.26 10.4 1.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.4 001315888.1_06925001_1 - 0.18 11.7 0.4 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HAD PF12710.5 001315913.1_06924001_1 - 1.2e-13 51.8 0.0 1.8e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.19 001315913.1_06924001_1 - 2.8e-06 26.9 0.0 6.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Heme_oxygenase PF01126.18 001315996.1_06922001_1 - 4.4e-09 36.3 0.1 5.8e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Heme oxygenase IZUMO PF15005.4 001315996.1_06922001_1 - 0.063 13.7 0.0 5.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated NAM PF02365.13 001315937.1_06922001_1 - 1.1e-27 96.5 0.1 2.1e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein Heme_oxygenase PF01126.18 001316158.1_06923001_2 - 1.9e-08 34.2 0.1 2.7e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Heme oxygenase SRF-TF PF00319.16 001316201.1_06922001_1 - 1.8e-24 84.8 0.2 3.2e-24 84.0 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001316201.1_06922001_1 - 2.9e-19 68.9 3.6 6.2e-19 67.8 3.6 1.6 1 0 0 1 1 1 1 K-box region DUF342 PF03961.11 001316201.1_06922001_1 - 0.15 10.5 1.7 0.16 10.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NAM PF02365.13 001316122.1_06923001_1 - 4.9e-29 100.9 0.5 1e-28 99.8 0.5 1.6 1 0 0 1 1 1 1 No apical meristem (NAM) protein WRKY PF03106.13 001315647.1_06922001_1 - 4e-27 94.2 4.3 1.1e-26 92.8 4.3 1.8 1 0 0 1 1 1 1 WRKY DNA -binding domain bHLH-MYC_N PF14215.4 001315974.1_06924001_2 - 7.4e-52 176.0 0.1 1.7e-51 174.8 0.1 1.6 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 001315974.1_06924001_2 - 1.1e-11 44.4 0.1 3.1e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ACT_4 PF13291.4 001315974.1_06924001_2 - 0.0054 17.2 0.0 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 ACT domain F1F0-ATPsyn_F PF10791.7 001315974.1_06924001_2 - 0.064 13.6 0.0 8.6 6.8 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Pkinase_Tyr PF07714.15 001316170.1_06924001_1 - 3.7e-73 245.9 0.1 5.3e-73 245.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001316170.1_06924001_1 - 9.7e-62 208.6 0.1 1.4e-61 208.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain ACT PF01842.23 001316170.1_06924001_1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain APH PF01636.21 001316170.1_06924001_1 - 0.0033 17.2 3.0 0.28 11.0 0.1 2.9 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.4 001316170.1_06924001_1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like AP2 PF00847.18 001315805.1_06924001_1 - 5.4e-23 80.9 7.6 1.7e-11 44.1 2.6 2.6 2 0 0 2 2 2 2 AP2 domain BBS2_N PF14781.4 001315805.1_06924001_1 - 0.027 14.1 1.7 0.037 13.6 0.6 1.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal STAC2_u1 PF16664.3 001315805.1_06924001_1 - 0.042 14.2 4.8 0.026 14.8 2.2 2.1 1 1 1 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Gln-synt_C PF00120.22 001316139.1_06924001_1 - 2.8e-16 59.3 0.0 5.2e-15 55.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001316139.1_06924001_1 - 1.6e-10 40.5 0.0 2.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Amino_oxidase PF01593.22 001316208.1_06924001_3 - 3e-79 267.3 0.0 3.5e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001316208.1_06924001_3 - 4.4e-15 55.5 0.1 8.9e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001316208.1_06924001_3 - 1.2e-08 34.8 0.0 0.00028 20.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 001316208.1_06924001_3 - 1.3e-06 27.8 0.0 0.00073 18.7 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001316208.1_06924001_3 - 2e-05 24.9 0.0 0.061 13.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001316208.1_06924001_3 - 0.00023 19.8 0.1 0.03 12.9 0.7 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.22 001316208.1_06924001_3 - 0.00083 18.4 0.7 0.0013 17.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.9 001316208.1_06924001_3 - 0.00096 17.9 0.0 0.38 9.4 0.0 2.1 2 0 0 2 2 2 2 MCRA family FAD_oxidored PF12831.5 001316208.1_06924001_3 - 0.0012 18.2 0.1 0.0019 17.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.15 001316208.1_06924001_3 - 0.0027 16.8 0.1 0.0047 16.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.17 001316208.1_06924001_3 - 0.003 16.8 0.1 0.0049 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.12 001316208.1_06924001_3 - 0.013 14.2 0.2 4.2 6.0 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.10 001316208.1_06924001_3 - 0.015 14.2 0.0 0.081 11.8 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.12 001316208.1_06924001_3 - 0.038 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RNase_H2-Ydr279 PF09468.8 001316208.1_06924001_3 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GIDA PF01134.20 001316208.1_06924001_3 - 0.49 9.3 1.3 0.76 8.6 0.7 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Acyl-ACP_TE PF01643.15 001316123.1_06923001_1 - 4.4e-81 271.7 0.2 1.8e-80 269.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-ACP thioesterase Acyl-thio_N PF12590.6 001316123.1_06923001_1 - 5.5e-51 172.4 1.2 8.4e-51 171.8 1.2 1.3 1 0 0 1 1 1 1 Acyl-ATP thioesterase 4HBT_2 PF13279.4 001316123.1_06923001_1 - 8.5e-06 26.1 0.0 0.0047 17.3 0.0 2.3 2 0 0 2 2 2 2 Thioesterase-like superfamily bZIP_1 PF00170.19 001316276.1_06923001_1 - 3.9e-11 42.7 17.5 7e-11 41.9 17.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001316276.1_06923001_1 - 1.1e-09 38.0 15.6 2.1e-09 37.2 15.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001316276.1_06923001_1 - 0.0021 18.4 11.9 0.008 16.5 10.5 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor KAsynt_C_assoc PF16197.3 001316276.1_06923001_1 - 0.07 13.5 1.6 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension WD40_alt PF14077.4 001316276.1_06923001_1 - 0.095 12.4 0.7 0.19 11.5 0.7 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF1501 PF07394.10 001316276.1_06923001_1 - 0.23 10.3 8.7 0.4 9.6 8.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1501) CALCOCO1 PF07888.9 001316276.1_06923001_1 - 0.35 9.3 9.6 0.47 8.8 9.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HAUS6_N PF14661.4 001316276.1_06923001_1 - 0.48 9.9 5.6 0.79 9.2 5.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4613 PF15390.4 001316276.1_06923001_1 - 0.59 8.3 4.0 0.85 7.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Pex14_N PF04695.11 001316276.1_06923001_1 - 0.69 10.5 8.7 0.064 13.8 1.3 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.11 001316276.1_06923001_1 - 1.3 8.8 18.0 1 9.2 16.2 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 60KD_IMP PF02096.18 001316276.1_06923001_1 - 4.2 7.1 5.2 7.6 6.3 5.2 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein HALZ PF02183.16 001315814.1_06924001_3 - 1.7e-17 63.2 3.6 4.2e-17 62.0 3.6 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper Homeobox PF00046.27 001315814.1_06924001_3 - 1.6e-15 56.5 5.0 3.1e-15 55.6 5.0 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001315814.1_06924001_3 - 0.0013 18.5 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain CASP_C PF08172.10 001315814.1_06924001_3 - 0.087 12.0 3.7 0.16 11.1 3.7 1.5 1 0 0 1 1 1 0 CASP C terminal Kinetocho_Slk19 PF12709.5 001315814.1_06924001_3 - 1.4 9.3 8.8 0.061 13.7 1.8 2.2 2 0 0 2 2 2 0 Central kinetochore-associated DUF972 PF06156.11 001315814.1_06924001_3 - 9.6 6.8 9.2 0.29 11.6 2.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pectinesterase PF01095.17 001316254.1_06924001_1 - 1e-132 441.2 0.1 1.3e-132 440.9 0.1 1.1 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.13 001316254.1_06924001_1 - 7.5e-13 49.0 0.2 1.2e-12 48.3 0.2 1.3 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Pectate_lyase_3 PF12708.5 001316254.1_06924001_1 - 0.011 15.5 1.0 0.039 13.7 1.0 2.0 1 1 0 1 1 1 0 Pectate lyase superfamily protein ArgoL1 PF08699.8 001316254.1_06924001_1 - 0.061 12.8 0.6 0.14 11.6 0.6 1.6 1 0 0 1 1 1 0 Argonaute linker 1 domain TrfA PF07042.9 001316254.1_06924001_1 - 0.072 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 TrfA protein EF-hand_1 PF00036.30 001315552.1_06922001_1 - 8.4e-21 71.8 8.2 2.8e-06 26.3 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.4 001315552.1_06922001_1 - 6.4e-18 63.0 4.8 6.2e-05 22.5 0.8 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001315552.1_06922001_1 - 7.4e-15 55.1 7.4 8e-10 38.9 0.7 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.4 001315552.1_06922001_1 - 4.1e-13 48.1 6.2 2.1e-07 30.0 0.1 4.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.4 001315552.1_06922001_1 - 6.2e-10 38.6 3.8 0.0011 18.6 0.2 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.5 001315552.1_06922001_1 - 0.00017 21.3 0.3 0.59 10.0 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001315552.1_06922001_1 - 0.00042 20.5 0.8 0.0062 16.7 0.2 2.6 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.4 001315552.1_06922001_1 - 0.081 13.1 0.2 0.99 9.7 0.0 2.7 2 2 1 3 3 3 0 EF-hand domain PHB_acc_N PF07879.9 001315552.1_06922001_1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain WRKY PF03106.13 001315614.1_06923001_1 - 4e-25 87.8 6.2 1e-24 86.5 6.2 1.8 1 0 0 1 1 1 1 WRKY DNA -binding domain 2OG-FeII_Oxy PF03171.18 001315580.1_06923001_1 - 1.6e-27 95.8 0.0 3.5e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001315580.1_06923001_1 - 3.6e-14 53.4 0.0 6.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PC-Esterase PF13839.4 001316182.1_06923001_1 - 1.4e-88 297.2 0.4 1.7e-88 296.9 0.4 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.4 001316182.1_06923001_1 - 1.5e-22 79.5 2.6 3.8e-22 78.2 2.6 1.7 1 0 0 1 1 1 1 PMR5 N terminal Domain Pectate_lyase_3 PF12708.5 001316265.1_06924001_3 - 1.8e-05 24.6 3.6 1.9e-05 24.5 0.3 2.0 2 0 0 2 2 2 1 Pectate lyase superfamily protein MecA_N PF05223.9 001316265.1_06924001_3 - 0.078 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain NAM PF02365.13 001315797.1_06923001_1 - 6.1e-26 91.0 0.0 1.3e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 No apical meristem (NAM) protein Pkinase PF00069.23 001316198.1_06923001_2 - 3.9e-70 236.1 0.0 4.8e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316198.1_06923001_2 - 1.6e-32 112.7 0.0 2.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001316198.1_06923001_2 - 1.3e-05 24.6 0.1 2.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001316198.1_06923001_2 - 0.0026 17.0 0.0 0.008 15.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.21 001316198.1_06923001_2 - 0.013 15.3 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aminotran_3 PF00202.19 001316296.1_06924001_1 - 1.2e-69 234.8 0.0 1.6e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III NTP_transferase PF00483.21 001316202.1_06924001_3 - 4.1e-67 226.2 0.0 5.2e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001316202.1_06924001_3 - 1.3e-05 25.5 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001316202.1_06924001_3 - 0.002 17.6 10.2 0.2 11.3 2.9 2.6 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Pkinase PF00069.23 001315564.1_06924001_1 - 1.6e-50 171.8 0.0 3.1e-50 170.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315564.1_06924001_1 - 4.2e-37 127.7 0.0 6.3e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FA_desaturase_2 PF03405.12 001315879.1_06923001_1 - 2.1e-159 529.5 0.0 2.4e-159 529.3 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.15 001315879.1_06923001_1 - 0.0012 19.1 0.0 0.71 10.1 0.1 2.6 2 0 0 2 2 2 2 Rubrerythrin DUF1580 PF07618.9 001315879.1_06923001_1 - 0.13 11.8 0.4 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) Aa_trans PF01490.16 001315975.1_06924001_1 - 9e-115 383.5 28.0 1.1e-114 383.3 28.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Exotox-A_cataly PF09009.8 001315975.1_06924001_1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A catalytic DUF868 PF05910.10 001165833.1_53724001_3 - 1.6e-47 162.4 0.0 2.4e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF868) UDPGT PF00201.16 151533.1_53726120_1 - 3.9e-14 52.2 0.1 6e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Chromo PF00385.22 151533.1_53726120_1 - 0.00054 19.7 0.5 0.0011 18.6 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain STAS_2 PF13466.4 151533.1_53726120_1 - 0.042 14.0 0.3 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 STAS domain TFIIA PF03153.11 001174652.1_53723001_1 - 8.3 6.2 7.3 11 5.8 7.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1191 PF06697.10 001174652.1_53723001_2 - 0.054 12.6 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.4 001174652.1_53723001_2 - 0.12 13.0 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LAX PF15681.3 001174652.1_53723001_2 - 0.16 10.5 0.2 0.25 9.9 0.2 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X TMEM100 PF16311.3 001174652.1_53723001_2 - 1.7 8.1 3.2 0.45 10.0 0.2 1.4 2 0 0 2 2 2 0 Transmembrane protein 100 OAD_gamma PF04277.11 001174652.1_53723001_2 - 3.1 8.3 0.0 3.1 8.3 0.0 3.0 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Cmc1 PF08583.8 001150802.2_53722001_3 - 2.8e-17 62.4 10.2 6.3e-17 61.2 10.2 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.11 001150802.2_53722001_3 - 0.032 14.2 4.6 0.12 12.4 3.8 2.5 1 1 1 2 2 2 0 CHCH domain DUF295 PF03478.16 001175071.1_53724001_3 - 5.5e-05 22.8 0.3 0.00017 21.2 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF295) F-box-like PF12937.5 001175071.1_53724001_3 - 0.71 9.7 3.8 0.19 11.5 0.4 1.8 2 0 0 2 2 2 0 F-box-like Peptidase_S28 PF05577.10 151616.1_53724120_2 - 1.6e-16 60.0 0.0 2.1e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S28 PF05577.10 151617.1_53723120_3 - 2.5e-17 62.7 0.0 3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 MatE PF01554.16 151622.1_53729120_2 - 1e-19 70.7 11.5 1.8e-19 69.8 11.5 1.4 1 0 0 1 1 1 1 MatE DUF4228 PF14009.4 001175565.1_53723001_2 - 1.9e-32 112.9 0.1 2.9e-32 112.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) WRKY PF03106.13 001316304.3_06923001_2 - 4.7e-26 90.8 3.5 9.9e-26 89.7 3.5 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain Chlorophyllase2 PF12740.5 001357101.1_53723001_1 - 5.9e-99 330.0 0.0 7.1e-99 329.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.9 001357101.1_53723001_1 - 1.4e-89 300.0 0.0 1.9e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.16 001357101.1_53723001_1 - 1.6e-06 27.7 0.0 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.11 001357101.1_53723001_1 - 4.1e-05 22.1 0.9 0.0013 17.2 0.1 2.5 2 1 1 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II PPR_2 PF13041.4 001175807.2_53726001_3 - 5.4e-95 311.3 17.9 9.9e-14 51.1 0.1 15.2 8 4 8 16 16 16 13 PPR repeat family PPR PF01535.18 001175807.2_53726001_3 - 1.6e-77 250.4 41.1 3e-07 30.1 0.0 20.1 20 0 0 20 20 20 15 PPR repeat PPR_1 PF12854.5 001175807.2_53726001_3 - 9.6e-57 188.2 9.7 3.8e-06 26.4 0.0 16.7 18 0 0 18 18 18 9 PPR repeat PPR_3 PF13812.4 001175807.2_53726001_3 - 2.3e-50 168.4 4.1 5.9e-08 32.5 0.0 9.6 8 1 1 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.2 001175807.2_53726001_3 - 6.4e-30 104.0 0.0 3.9e-10 39.3 0.0 6.1 3 1 3 6 6 6 5 Pentacotripeptide-repeat region of PROPR ECSIT PF06239.9 001175807.2_53726001_3 - 9.6e-07 28.0 0.8 0.23 10.4 0.0 4.8 2 2 1 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway Clathrin PF00637.18 001175807.2_53726001_3 - 6.1e-05 22.8 1.9 0.13 12.0 0.0 4.9 4 1 1 5 5 5 1 Region in Clathrin and VPS MRP-S27 PF10037.7 001175807.2_53726001_3 - 0.0052 15.6 0.1 2 7.1 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.4 001175807.2_53726001_3 - 0.0061 16.9 1.4 0.55 10.6 0.1 4.5 5 1 1 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.7 001175807.2_53726001_3 - 0.051 13.1 2.1 51 3.3 0.0 5.1 6 1 1 7 7 7 0 26S proteasome subunit RPN7 TPR_10 PF13374.4 001175807.2_53726001_3 - 0.078 12.8 0.0 10 6.0 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.4 001175807.2_53726001_3 - 0.15 12.2 5.4 5.6 7.3 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.4 001175807.2_53726001_3 - 0.4 11.0 1.7 20 5.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.4 001175807.2_53726001_3 - 2.5 9.0 11.4 1e+02 4.0 0.7 6.6 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_1 PF00515.26 001175807.2_53726001_3 - 8 6.3 11.8 23 4.9 0.0 6.2 9 0 0 9 9 9 0 Tetratricopeptide repeat zf-RVT PF13966.4 151633.1_53728120_1 - 0.028 15.1 0.3 0.16 12.7 0.0 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase zf-RVT PF13966.4 151633.1_53728120_3 - 9e-12 45.5 0.6 2.2e-11 44.3 0.6 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Hydrolase_4 PF12146.6 151635.1_53723120_1 - 8e-16 57.9 0.0 1.2e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.18 151635.1_53723120_1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 151635.1_53723120_3 - 0.034 13.3 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4228 PF14009.4 001176047.2_53728001_3 - 2.9e-24 86.3 0.1 5e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) Lyase_aromatic PF00221.17 001316185.1_06925001_3 - 1.2e-149 498.9 1.5 1.5e-149 498.5 1.5 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase FAD_binding_6 PF00970.22 151639.1_53724120_2 - 8e-08 32.4 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Transpos_assoc PF13963.4 151659.1_53724120_1 - 2.1e-07 31.3 0.1 5.1e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 Transposase-associated domain A2L_zn_ribbon PF08792.8 151659.1_53724120_1 - 0.24 11.0 0.7 0.84 9.3 0.7 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain ATP-synt_Eps PF04627.11 001112125.2_53721001_3 - 5.2e-24 83.8 0.0 8.4e-24 83.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain ADH_N PF08240.10 001112015.1_53723001_1 - 1.5e-24 85.9 2.8 2.7e-24 85.0 2.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.24 001112015.1_53723001_1 - 7.8e-24 83.9 0.4 1.9e-23 82.7 0.4 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.12 001112015.1_53723001_1 - 0.0019 17.7 0.1 0.003 17.0 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.17 001112015.1_53723001_1 - 0.0021 17.3 0.1 0.0036 16.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.16 001112015.1_53723001_1 - 0.0058 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N_2 PF13602.4 001112015.1_53723001_1 - 0.13 13.2 0.0 0.27 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Cofilin_ADF PF00241.18 001112004.1_53722001_1 - 4.1e-34 117.4 0.7 5.1e-34 117.0 0.7 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CAP_N PF01213.17 001112004.1_53722001_1 - 1.3 8.3 6.5 2 7.7 6.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Erythro-docking PF09277.9 001147291.1_53724001_2 - 0.18 11.6 5.6 0.041 13.6 1.2 2.2 2 0 0 2 2 2 0 Erythronolide synthase, docking p450 PF00067.20 001294304.1_53724001_2 - 1.4e-91 307.4 0.0 1.9e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tubulin PF00091.23 001111854.1_53724001_1 - 2e-67 227.1 0.0 2.8e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001111854.1_53724001_1 - 2.2e-50 169.9 0.1 3.4e-50 169.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001111854.1_53724001_1 - 0.0059 16.2 0.0 0.028 14.0 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Pollen_allerg_1 PF01357.19 001111739.1_53723001_3 - 2.2e-26 91.6 0.0 4.1e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001111739.1_53723001_3 - 3e-16 59.4 0.3 7.5e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 Lytic transglycolase SHMT PF00464.17 001288557.1_48624001_3 - 1e-211 702.5 0.0 1.2e-211 702.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.19 001288557.1_48624001_3 - 0.00069 18.8 0.0 0.0016 17.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II PFK PF00365.18 001288429.1_48625001_2 - 7.3e-28 97.6 0.0 3.1e-27 95.5 0.0 1.8 1 1 0 1 1 1 1 Phosphofructokinase Lipoxygenase PF00305.17 001287987.1_48626001_3 - 0 1083.5 0.0 0 1083.3 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001287987.1_48626001_3 - 4.8e-21 75.4 0.2 1.4e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 PLAT/LH2 domain PALP PF00291.23 001288260.2_48623001_1 - 1.7e-62 211.3 0.1 2.8e-62 210.7 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NTP_transferase PF00483.21 001288466.1_48624001_1 - 9e-71 238.2 0.0 1.2e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001288466.1_48624001_1 - 0.0016 18.7 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001288466.1_48624001_1 - 0.0055 16.3 7.2 0.021 14.4 1.1 3.2 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.10 001288466.1_48624001_1 - 0.14 11.0 0.4 15 4.3 0.1 2.8 2 1 1 3 3 3 0 L-fucokinase Tubulin PF00091.23 001288449.1_48623001_1 - 7.3e-70 235.0 0.0 1.2e-69 234.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001288449.1_48623001_1 - 1.5e-39 134.9 0.4 2.3e-39 134.4 0.4 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001288449.1_48623001_1 - 0.00073 19.7 0.0 0.0023 18.1 0.0 1.9 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.4 001288449.1_48623001_1 - 0.0014 17.8 0.0 0.0052 15.9 0.0 1.8 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.4 001288449.1_48623001_1 - 0.0019 17.8 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Catalase PF00199.17 001287934.1_48624001_2 - 2.1e-169 563.5 0.0 2.5e-169 563.3 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.10 001287934.1_48624001_2 - 5e-14 52.1 0.0 1.1e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive PK PF00224.19 001288156.1_48624001_2 - 1.7e-160 533.5 0.9 2.2e-160 533.1 0.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.14 001288156.1_48624001_2 - 3.8e-26 91.5 0.4 9e-26 90.3 0.4 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.12 001288156.1_48624001_2 - 0.088 11.8 0.2 0.21 10.5 0.2 1.7 1 1 1 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family PGM_PMM_I PF02878.14 001288404.1_48624001_1 - 8.4e-33 112.9 0.1 1.4e-32 112.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.14 001288404.1_48624001_1 - 3.1e-29 101.4 0.0 6.4e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.14 001288404.1_48624001_1 - 3e-12 46.9 0.0 6.5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.18 001288404.1_48624001_1 - 1.2e-06 28.4 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain G-alpha PF00503.18 001288212.1_48623001_1 - 1.4e-94 317.0 6.0 1.8e-94 316.7 6.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001288212.1_48623001_1 - 3.8e-11 42.6 0.3 2.3e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_21 PF13304.4 001288212.1_48623001_1 - 0.015 15.0 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Gtr1_RagA PF04670.10 001288212.1_48623001_1 - 0.023 13.9 0.3 5.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.4 001288212.1_48623001_1 - 0.16 11.6 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myb_DNA-binding PF00249.29 001288417.1_48623001_3 - 1.4e-11 44.2 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001288417.1_48623001_3 - 0.00099 19.2 0.1 0.0018 18.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001288417.1_48623001_3 - 0.063 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Myb DNA-binding like G6PD_C PF02781.14 001288109.1_48625001_2 - 1.2e-110 369.2 0.0 1.6e-110 368.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.20 001288109.1_48625001_2 - 4.6e-57 193.4 0.0 7.1e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glyco_transf_5 PF08323.9 001288145.1_48625001_2 - 9.2e-65 218.6 0.0 2.6e-64 217.1 0.0 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 001288145.1_48625001_2 - 1.8e-17 63.3 0.0 4.2e-17 62.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001288145.1_48625001_2 - 5.4e-13 49.4 0.0 1.4e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.4 001288145.1_48625001_2 - 0.2 12.0 1.4 0.58 10.4 1.4 1.9 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Cytochrom_C1 PF02167.13 001288448.1_48623001_2 - 5.8e-95 317.0 0.0 7.1e-95 316.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.4 001288448.1_48623001_2 - 0.0013 18.8 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.19 001288448.1_48623001_2 - 0.02 15.9 0.0 0.05 14.6 0.0 1.8 1 0 0 1 1 1 0 Cytochrome c Gp_dh_N PF00044.22 001288448.1_48623001_2 - 0.12 12.5 0.3 0.3 11.3 0.2 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CN_hydrolase PF00795.20 001288196.1_48623001_2 - 5.4e-53 179.8 0.0 6.5e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acyl-CoA_dh_1 PF00441.22 001288114.1_48623001_1 - 2.5e-44 151.0 0.0 4.3e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.14 001288114.1_48623001_1 - 4.8e-35 120.5 0.0 8.6e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.17 001288114.1_48623001_1 - 2.2e-26 91.8 0.1 3.6e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.9 001288114.1_48623001_1 - 2e-13 50.6 0.0 3.7e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.6 001288114.1_48623001_1 - 0.00027 20.6 0.1 0.0012 18.5 0.1 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Glycos_transf_1 PF00534.18 001288314.1_48628001_3 - 1e-25 90.2 0.0 1.7e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001288314.1_48628001_3 - 2.9e-15 56.7 0.0 6.1e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sucrose_synth PF00862.17 001288314.1_48628001_3 - 2.1e-11 42.7 0.0 9.9e-11 40.5 0.0 1.8 1 1 0 1 1 1 1 Sucrose synthase S6PP PF05116.11 001288314.1_48628001_3 - 8.8e-09 35.1 0.0 2.4e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Glyco_transf_4 PF13439.4 001288314.1_48628001_3 - 0.00019 21.4 0.0 0.0027 17.6 0.0 2.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 DUF1752 PF08550.8 001288314.1_48628001_3 - 0.0045 16.7 4.3 0.013 15.2 4.3 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_trans_4_4 PF13579.4 001288314.1_48628001_3 - 0.0089 16.3 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.4 001288314.1_48628001_3 - 0.025 14.8 0.0 0.083 13.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 CytB6-F_Fe-S PF08802.8 001287956.1_48622001_1 - 2.6e-20 72.0 1.3 5.8e-20 70.9 1.3 1.6 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit Rieske PF00355.24 001287956.1_48622001_1 - 4.9e-13 48.7 0.1 8.5e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain WHAMM-JMY_N PF15920.3 001287956.1_48622001_1 - 0.034 13.9 0.6 0.055 13.2 0.6 1.3 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated HPTransfase PF10090.7 001287956.1_48622001_1 - 0.098 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphotransferase NAD_binding_6 PF08030.10 001288375.1_48628001_2 - 9.2e-53 178.4 0.0 1.9e-52 177.4 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NADPH_Ox PF08414.8 001288375.1_48628001_2 - 1.4e-40 137.5 1.5 3.4e-40 136.3 1.5 1.7 1 0 0 1 1 1 1 Respiratory burst NADPH oxidase FAD_binding_8 PF08022.10 001288375.1_48628001_2 - 6.2e-34 116.2 0.0 1.2e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.17 001288375.1_48628001_2 - 9.5e-20 70.9 2.8 9.5e-20 70.9 2.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.4 001288375.1_48628001_2 - 2.6e-05 24.5 0.8 0.00047 20.5 0.1 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.30 001288375.1_48628001_2 - 0.00047 19.4 0.3 0.0052 16.1 0.6 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.4 001288375.1_48628001_2 - 0.0022 17.6 0.1 0.029 14.2 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.4 001288375.1_48628001_2 - 0.0098 15.3 4.7 0.029 13.8 0.6 2.7 2 0 0 2 2 2 1 EF hand DUF1367 PF07105.9 001288375.1_48628001_2 - 0.051 13.1 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) Oxidored_q6 PF01058.20 001288694.1_48622001_3 - 2.6e-22 78.9 0.1 3.8e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit PGM_PMM_I PF02878.14 001288352.1_48625001_2 - 2.9e-34 117.6 0.0 4.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.14 001288352.1_48625001_2 - 1.4e-28 99.3 0.0 3.5e-28 97.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.14 001288352.1_48625001_2 - 1.1e-11 45.1 0.0 2.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.18 001288352.1_48625001_2 - 1.3e-06 28.3 0.0 3.9e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain 14-3-3 PF00244.18 001288133.1_48623001_3 - 5.5e-104 346.4 3.3 7.3e-104 346.0 3.3 1.2 1 0 0 1 1 1 1 14-3-3 protein DUF3810 PF12725.5 001288133.1_48623001_3 - 0.5 9.5 5.0 0.15 11.3 0.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) Peptidase_M16 PF00675.18 001288125.1_48624001_2 - 1.5e-53 180.6 0.2 2.2e-53 180.1 0.2 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001288125.1_48624001_2 - 3.8e-37 127.9 0.0 4e-36 124.6 0.0 2.2 2 1 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.9 001288125.1_48624001_2 - 0.027 13.5 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16C associated Malic_M PF03949.13 001288349.1_48625001_2 - 2.2e-90 302.3 0.2 2.9e-90 301.9 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.17 001288349.1_48625001_2 - 8.6e-77 256.9 0.0 1.3e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Barwin PF00967.15 001288699.1_48622001_1 - 2.4e-65 217.7 4.7 2.4e-65 217.7 4.7 1.6 2 0 0 2 2 2 1 Barwin family Chitin_bind_1 PF00187.17 001288699.1_48622001_1 - 4.8e-13 49.2 22.0 4.8e-13 49.2 22.0 2.8 3 0 0 3 3 3 1 Chitin recognition protein G6PD_C PF02781.14 001288468.1_48624001_2 - 2.8e-116 387.6 0.0 3.7e-116 387.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.20 001288468.1_48624001_2 - 5.4e-58 196.4 0.0 8.3e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain WD40 PF00400.30 001287957.1_48624001_3 - 1.2e-36 123.9 28.0 3e-07 30.9 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001287957.1_48624001_3 - 1.2e-13 51.0 0.1 0.004 17.3 0.0 4.9 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001287957.1_48624001_3 - 0.00083 18.3 0.2 3.1 6.5 0.0 3.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein GDA1_CD39 PF01150.15 001288419.1_48623001_1 - 2.7e-147 490.7 0.0 3e-147 490.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.14 001288419.1_48623001_1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family EF-hand_1 PF00036.30 001288430.1_48622001_3 - 2.9e-40 132.7 12.2 1.2e-09 36.9 0.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001288430.1_48622001_3 - 1.7e-34 118.0 4.2 1.2e-17 64.0 1.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001288430.1_48622001_3 - 5.5e-30 102.8 9.4 2.6e-14 52.6 0.5 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001288430.1_48622001_3 - 5.5e-29 97.5 7.4 4.3e-09 35.5 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001288430.1_48622001_3 - 2.3e-24 83.6 9.3 3.3e-06 26.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001288430.1_48622001_3 - 3.9e-16 59.0 0.3 5.6e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001288430.1_48622001_3 - 2.6e-08 33.6 1.4 0.00024 20.9 0.3 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001288430.1_48622001_3 - 3.2e-07 30.5 1.3 0.0065 16.6 0.2 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001288430.1_48622001_3 - 5.3e-05 23.9 0.1 0.0013 19.5 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.11 001288430.1_48622001_3 - 9.7e-05 22.2 0.0 0.11 12.4 0.0 2.8 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.8 001288430.1_48622001_3 - 0.0009 19.2 0.8 0.0029 17.5 0.3 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.14 001288430.1_48622001_3 - 0.0012 19.0 0.3 2.1 8.5 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb4 Caleosin PF05042.11 001288430.1_48622001_3 - 0.0049 16.7 0.1 0.96 9.2 0.0 2.9 1 1 2 3 3 3 1 Caleosin related protein DUF3349 PF11829.6 001288430.1_48622001_3 - 0.014 16.0 0.3 7.7 7.2 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) MotA_activ PF09114.8 001288430.1_48622001_3 - 0.02 14.9 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain TerB PF05099.11 001288430.1_48622001_3 - 0.041 13.7 0.2 11 5.9 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB SurA_N_2 PF13623.4 001288430.1_48622001_3 - 0.075 12.8 1.1 1.9 8.2 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain Poly_export PF02563.14 001288430.1_48622001_3 - 0.079 13.1 0.0 3.2 7.9 0.0 2.6 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein GPHH PF16905.3 001288430.1_48622001_3 - 0.14 11.8 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Peptidase_M16 PF00675.18 001288239.1_48625001_2 - 9.8e-44 148.8 0.1 3.6e-43 147.0 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001288239.1_48625001_2 - 4.1e-30 105.0 0.0 6.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain NAD_binding_6 PF08030.10 001288052.1_48626001_1 - 6.5e-53 178.9 0.1 2.6e-52 176.9 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NADPH_Ox PF08414.8 001288052.1_48626001_1 - 9.7e-39 131.6 1.1 2.5e-38 130.3 0.4 2.1 2 0 0 2 2 2 1 Respiratory burst NADPH oxidase FAD_binding_8 PF08022.10 001288052.1_48626001_1 - 1.4e-33 115.1 0.0 3.7e-33 113.7 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.17 001288052.1_48626001_1 - 5.3e-21 74.9 1.6 5.3e-21 74.9 1.6 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.4 001288052.1_48626001_1 - 4.6e-06 26.9 0.9 1.2e-05 25.5 0.1 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.4 001288052.1_48626001_1 - 6.3e-06 25.6 0.2 0.00012 21.6 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.30 001288052.1_48626001_1 - 4.4e-05 22.6 1.2 0.00053 19.2 0.2 3.1 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.4 001288052.1_48626001_1 - 0.0013 18.0 3.6 0.0056 16.0 0.4 3.0 3 0 0 3 3 3 1 EF hand DUF1430 PF07242.9 001288052.1_48626001_1 - 0.72 10.0 16.5 0.25 11.5 7.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) RuBisCO_small PF00101.18 001288315.1_48622001_1 - 4.9e-40 135.3 0.0 6.6e-40 134.9 0.0 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain RbcS PF12338.6 001288315.1_48622001_1 - 1.8e-21 75.9 8.9 2.7e-21 75.3 8.9 1.2 1 0 0 1 1 1 1 Ribulose-1,5-bisphosphate carboxylase small subunit 14-3-3 PF00244.18 001288333.1_48623001_3 - 9.7e-102 339.0 4.0 1.2e-101 338.7 4.0 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.9 001288333.1_48623001_3 - 0.14 12.0 6.7 0.15 11.9 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF837) Orbi_VP5 PF00901.15 001288333.1_48623001_3 - 0.26 9.5 3.7 0.42 8.8 3.7 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Glyco_transf_5 PF08323.9 001287989.1_48624001_1 - 7.3e-72 241.9 0.0 1.2e-71 241.1 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 001287989.1_48624001_1 - 3.2e-16 59.3 0.1 5.4e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001287989.1_48624001_1 - 2.2e-10 41.0 0.2 3.9e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001287989.1_48624001_1 - 0.0032 17.4 0.0 0.39 10.6 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase Family 4 UCR_14kD PF02271.14 001287958.1_48622001_1 - 1e-26 92.7 1.9 1.3e-26 92.3 1.9 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit PsbP PF01789.14 001288020.1_48623001_2 - 2.1e-38 131.8 0.0 2.8e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 PsbP PsbQ PF05757.9 001288020.1_48623001_2 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Rieske PF00355.24 001288698.1_48623001_2 - 2.2e-12 46.6 0.0 4.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.12 001288698.1_48623001_2 - 7.2e-12 45.5 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region K-box PF01486.15 001288213.1_48623001_3 - 3.2e-28 97.6 10.5 8e-28 96.3 10.5 1.7 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001288213.1_48623001_3 - 6.2e-25 86.3 0.3 1.2e-24 85.4 0.3 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FliD_C PF07195.10 001288213.1_48623001_3 - 0.0067 15.7 4.9 0.011 15.1 4.9 1.3 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus DUF3584 PF12128.6 001288213.1_48623001_3 - 0.0085 13.5 10.2 0.011 13.2 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) IncA PF04156.12 001288213.1_48623001_3 - 3.8 7.1 11.1 6.1 6.5 11.1 1.4 1 0 0 1 1 1 0 IncA protein DUF1640 PF07798.9 001288213.1_48623001_3 - 7.7 6.4 14.7 13 5.6 13.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) PALP PF00291.23 001288115.1_48623001_3 - 6.7e-65 219.3 0.0 7.8e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CPSase_sm_chain PF00988.20 001288115.1_48623001_3 - 0.14 11.9 0.1 0.36 10.5 0.1 1.7 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain NmrA PF05368.11 001287994.1_48623001_2 - 5.5e-87 291.0 0.5 6.1e-87 290.9 0.5 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.4 001287994.1_48623001_2 - 1.5e-13 50.9 0.0 2.3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.19 001287994.1_48623001_2 - 5.9e-09 35.6 0.2 1.6e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001287994.1_48623001_2 - 1.3e-06 27.9 0.1 2.2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.16 001287994.1_48623001_2 - 5.4e-06 26.5 0.2 1.2e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.17 001287994.1_48623001_2 - 1.1e-05 24.5 0.2 1.5e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.8 001287994.1_48623001_2 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.23 001287994.1_48623001_2 - 0.0018 17.6 0.1 0.0026 17.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.15 001287994.1_48623001_2 - 0.02 15.3 0.2 0.077 13.5 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glu_dehyd_C PF16912.3 001287994.1_48623001_2 - 0.027 13.8 0.1 0.061 12.7 0.1 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus TrkA_N PF02254.16 001287994.1_48623001_2 - 0.047 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.13 001287994.1_48623001_2 - 0.1 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PFK PF00365.18 001288395.1_48624001_1 - 4.2e-37 127.9 0.0 3.3e-36 125.0 0.0 1.9 1 1 0 1 1 1 1 Phosphofructokinase ADH_zinc_N PF00107.24 001288151.1_48623001_3 - 2.4e-26 92.0 0.1 4.1e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001288151.1_48623001_3 - 1.1e-23 83.0 0.7 2.4e-23 82.0 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.3 001288151.1_48623001_3 - 4.6e-05 22.9 0.0 0.00011 21.6 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.19 001288151.1_48623001_3 - 0.0014 17.9 0.5 0.0022 17.2 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.17 001288151.1_48623001_3 - 0.011 14.9 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.12 001288151.1_48623001_3 - 0.058 12.8 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.10 001288151.1_48623001_3 - 0.077 12.4 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.16 001288151.1_48623001_3 - 0.089 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain CTNNBL PF08216.9 001288151.1_48623001_3 - 0.18 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear PsbR PF04725.10 001288244.1_48621001_1 - 1.4e-51 172.7 4.4 1.7e-51 172.5 4.4 1.1 1 0 0 1 1 1 1 Photosystem II 10 kDa polypeptide PsbR Glyco_hydro_17 PF00332.16 001287940.1_48623001_2 - 6.6e-137 455.9 0.0 7.8e-137 455.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Ribosomal_S4e PF00900.18 001288219.1_48622001_1 - 2e-35 120.4 0.2 5.1e-35 119.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.3 001288219.1_48622001_1 - 1.3e-25 88.7 0.0 2.6e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.10 001288219.1_48622001_1 - 9.4e-20 70.3 6.1 2.3e-19 69.1 6.1 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.27 001288219.1_48622001_1 - 2.9e-07 30.1 2.6 1.9e-06 27.5 2.7 2.2 2 0 0 2 2 2 1 KOW motif S4 PF01479.23 001288219.1_48622001_1 - 3e-06 26.7 0.1 6.4e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 S4 domain Sipho_tail PF05709.9 001288219.1_48622001_1 - 0.005 16.2 0.2 2.1 7.6 0.0 2.1 2 0 0 2 2 2 2 Phage tail protein 14-3-3 PF00244.18 001287947.1_48623001_2 - 1.1e-104 348.6 2.4 1.3e-104 348.4 2.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Lipoxygenase PF00305.17 001287914.1_48626001_2 - 0 1035.8 0.0 0 1035.6 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001287914.1_48626001_2 - 7.3e-10 39.3 0.1 1.8e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain Lipoxygenase PF00305.17 001288428.1_48626001_3 - 0 1064.8 0.0 0 1064.6 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001288428.1_48626001_3 - 1.2e-19 70.9 0.1 2.3e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Lipoxygenase PF00305.17 001288186.1_48627001_2 - 0 1031.0 0.0 0 1030.6 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001288186.1_48627001_2 - 9.5e-15 55.1 0.5 2.4e-14 53.8 0.2 1.9 2 1 0 2 2 2 1 PLAT/LH2 domain PALP PF00291.23 001288065.1_48624001_3 - 1.7e-48 165.4 0.0 2.1e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme OKR_DC_1_N PF03709.13 001288065.1_48624001_3 - 0.034 14.3 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Pyrophosphatase PF00719.17 001288029.1_48622001_2 - 6.2e-53 178.7 0.1 7.7e-53 178.4 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Ldh_1_N PF00056.21 001315933.1_06923001_3 - 8.3e-47 158.7 0.1 1.2e-46 158.2 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001315933.1_06923001_3 - 1.2e-42 145.5 0.0 1.9e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.17 001315933.1_06923001_3 - 0.00041 19.3 0.0 0.00061 18.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.18 001315933.1_06923001_3 - 0.03 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.22 001315933.1_06923001_3 - 0.078 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L13e PF01294.16 001315978.1_06922001_2 - 4e-77 258.0 4.9 5.2e-77 257.6 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e SBP PF03110.12 001112073.2_53723001_3 - 5.3e-31 106.5 15.2 1e-30 105.6 15.2 1.5 1 0 0 1 1 1 1 SBP domain PALP PF00291.23 001318691.1_48623001_2 - 4e-67 226.6 0.0 4.6e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CPSase_sm_chain PF00988.20 001318691.1_48623001_2 - 0.098 12.4 0.1 0.25 11.0 0.1 1.8 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain Glyco_hydro_19 PF00182.17 001315926.1_06923001_2 - 4.6e-46 157.4 11.8 3.2e-37 128.5 5.4 2.9 1 1 1 2 2 2 2 Chitinase class I Chitin_bind_1 PF00187.17 001315926.1_06923001_2 - 5.6e-08 33.0 19.2 5.6e-08 33.0 19.2 3.1 4 0 0 4 4 4 1 Chitin recognition protein Cpn60_TCP1 PF00118.22 001316056.1_06924001_1 - 1.2e-77 261.5 16.9 2.5e-77 260.4 16.9 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lycopene_cycl PF05834.10 001318672.1_48623001_1 - 6.7e-154 512.4 0.0 7.8e-154 512.2 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.12 001318672.1_48623001_1 - 1.5e-07 30.8 0.0 9.4e-07 28.2 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001318672.1_48623001_1 - 5.6e-06 25.7 0.0 8.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.15 001318672.1_48623001_1 - 4e-05 22.9 0.0 0.0015 17.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.12 001318672.1_48623001_1 - 0.00023 20.0 0.2 0.0091 14.8 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.12 001318672.1_48623001_1 - 0.0003 19.5 0.0 0.0011 17.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.22 001318672.1_48623001_1 - 0.00052 19.1 0.0 0.00085 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.4 001318672.1_48623001_1 - 0.00098 18.3 0.3 0.0045 16.1 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001318672.1_48623001_1 - 0.0025 17.4 0.1 1.3 8.5 0.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.4 001318672.1_48623001_1 - 0.0086 16.0 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.4 001318672.1_48623001_1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.25 001318672.1_48623001_1 - 0.031 14.7 0.1 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001318672.1_48623001_1 - 0.086 11.8 0.0 0.17 10.8 0.0 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.17 001318672.1_48623001_1 - 0.12 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Metallothio_Cad PF07846.9 001318672.1_48623001_1 - 0.14 12.1 1.4 14 5.7 0.6 2.8 2 0 0 2 2 2 0 Metallothionein family NAD_binding_7 PF13241.4 001318672.1_48623001_1 - 0.16 12.2 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.4 001318672.1_48623001_1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain NTP_transferase PF00483.21 001318669.1_48625001_1 - 3.2e-77 259.4 0.0 7.2e-77 258.2 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.22 001318669.1_48625001_1 - 0.14 11.8 9.2 0.077 12.6 1.5 3.1 3 0 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) K-box PF01486.15 001316131.1_06923001_3 - 3.8e-27 94.2 4.4 6.7e-27 93.4 4.4 1.3 1 0 0 1 1 1 1 K-box region SRF-TF PF00319.16 001316131.1_06923001_3 - 1e-26 92.0 0.2 1.7e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Pyr_redox_2 PF07992.12 001318655.1_48624001_2 - 7.3e-57 192.7 0.0 9.1e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001318655.1_48624001_2 - 8.1e-08 32.6 0.1 5.6e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lipoxygenase PF00305.17 001318678.1_48626001_2 - 0 1068.3 0.0 0 1068.0 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001318678.1_48626001_2 - 4.9e-18 65.7 0.0 9.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Citrate_synt PF00285.19 001318632.1_48624001_1 - 1.2e-92 310.7 0.0 1.4e-92 310.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Smr PF01713.19 001318632.1_48624001_1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Smr domain p450 PF00067.20 001318588.1_48623001_1 - 2.8e-21 75.7 0.0 3e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Amino_oxidase PF01593.22 001112139.2_53725001_3 - 1.7e-68 231.8 0.0 2e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001112139.2_53725001_3 - 2.8e-14 53.0 0.1 5.3e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001112139.2_53725001_3 - 5.9e-07 29.3 0.1 1.6e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.12 001112139.2_53725001_3 - 0.00028 20.1 0.0 0.00073 18.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001112139.2_53725001_3 - 0.00036 19.2 0.1 0.00061 18.5 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.5 001112139.2_53725001_3 - 0.0006 19.1 0.0 0.00079 18.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.22 001112139.2_53725001_3 - 0.0013 17.8 0.1 0.002 17.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.9 001112139.2_53725001_3 - 0.0033 16.1 0.0 0.089 11.4 0.0 2.1 2 0 0 2 2 2 1 MCRA family FAD_binding_3 PF01494.17 001112139.2_53725001_3 - 0.0059 15.8 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.20 001112139.2_53725001_3 - 0.017 14.1 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.16 001112139.2_53725001_3 - 0.049 13.4 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.4 001112139.2_53725001_3 - 0.053 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.25 001112139.2_53725001_3 - 0.074 13.5 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.4 001112139.2_53725001_3 - 0.17 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.19 001112139.2_53725001_3 - 0.21 10.7 0.0 0.5 9.5 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.17 001157345.2_53724001_2 - 1.3e-59 201.9 0.0 4.7e-39 134.1 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 001157345.2_53724001_2 - 5.3e-22 78.3 0.0 9.1e-16 57.8 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.12 001157345.2_53724001_2 - 1.3e-16 60.6 0.0 4.5e-16 58.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001157345.2_53724001_2 - 4.1e-09 36.4 0.3 0.0016 18.0 0.4 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.4 001157345.2_53724001_2 - 2.1e-08 34.1 0.2 5.7e-08 32.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.4 001157345.2_53724001_2 - 3.6e-05 23.7 0.7 0.0011 18.8 0.2 3.0 2 2 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.22 001157345.2_53724001_2 - 5.4e-05 22.3 1.0 0.00032 19.8 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.22 001157345.2_53724001_2 - 0.00016 21.0 0.3 0.037 13.2 0.6 2.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.4 001157345.2_53724001_2 - 0.00056 19.0 0.1 0.0029 16.7 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.15 001157345.2_53724001_2 - 0.00056 19.1 0.6 0.0023 17.1 0.3 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.12 001157345.2_53724001_2 - 0.00069 18.3 0.2 0.0015 17.2 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.25 001157345.2_53724001_2 - 0.00072 19.9 1.2 0.23 11.9 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 001157345.2_53724001_2 - 0.0016 17.7 0.8 0.022 13.9 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.5 001157345.2_53724001_2 - 0.013 14.8 0.1 0.025 13.8 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pkinase PF00069.23 001357546.1_53726001_3 - 4.9e-43 147.2 0.0 6.5e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001357546.1_53726001_3 - 2.9e-40 138.0 0.0 4.1e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.4 001357546.1_53726001_3 - 4.8e-08 32.5 23.4 0.015 15.0 1.4 5.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat ABC1 PF03109.14 001357546.1_53726001_3 - 0.00041 20.4 0.0 0.00087 19.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family SKG6 PF08693.8 001357546.1_53726001_3 - 0.0057 15.9 2.4 0.014 14.7 2.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain APH PF01636.21 001357546.1_53726001_3 - 0.0088 15.9 2.9 1.1 8.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.14 001357695.1_53725001_2 - 7.3e-34 116.3 0.0 1.2e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.21 001357695.1_53725001_2 - 0.00031 20.6 0.2 0.0099 15.7 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.23 001357695.1_53725001_2 - 0.013 14.7 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain DUF4220 PF13968.4 001357716.1_53725001_1 - 0.0034 16.9 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4220) DUF4220 PF13968.4 001357716.1_53725001_3 - 4.9e-05 22.9 0.0 7.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4220) p450 PF00067.20 001357735.1_53724001_2 - 1.4e-53 182.2 0.0 1.7e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LEA_2 PF03168.11 001196635.1_53722001_1 - 4.7e-08 33.3 0.0 6.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein Thymidylat_synt PF00303.17 001348567.1_53725001_2 - 2.2e-116 387.5 0.0 2.8e-116 387.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.17 001348567.1_53725001_2 - 4.7e-35 120.5 0.0 1.3e-34 119.1 0.0 1.7 2 0 0 2 2 2 1 Dihydrofolate reductase AP2 PF00847.18 001176924.1_53723001_1 - 3.4e-13 49.5 0.7 6.1e-13 48.7 0.7 1.4 1 0 0 1 1 1 1 AP2 domain PALP PF00291.23 001288049.2_48623001_3 - 5e-68 229.5 0.3 5.8e-68 229.3 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Response_reg PF00072.22 001357737.1_53726001_1 - 2.1e-22 79.3 0.0 3.3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain CCT PF06203.12 001357737.1_53726001_1 - 7.2e-18 64.3 7.6 2e-17 62.8 7.6 1.8 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.8 001357737.1_53726001_1 - 0.077 12.8 2.6 0.14 11.9 2.6 1.4 1 0 0 1 1 1 0 Divergent CCT motif RA PF00788.21 001357737.1_53726001_1 - 0.092 13.3 0.1 1 9.9 0.0 2.6 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain DUF295 PF03478.16 001301529.1_53724001_3 - 2.4e-06 27.1 0.5 1.7e-05 24.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF295) polyprenyl_synt PF00348.15 001197002.2_53723001_2 - 1.6e-51 174.7 0.0 2.6e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase UbiA PF01040.16 001197002.2_53723001_2 - 0.0026 16.9 1.9 0.0032 16.7 0.4 1.8 2 0 0 2 2 2 1 UbiA prenyltransferase family AP2 PF00847.18 001196774.1_53723001_2 - 2.3e-11 43.6 2.1 4.1e-11 42.8 2.1 1.4 1 0 0 1 1 1 1 AP2 domain PBP1_TM PF14812.4 001196774.1_53723001_2 - 0.026 14.8 0.4 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DTW PF03942.13 001153301.1_53723001_1 - 8.8e-36 123.3 0.0 1.1e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 DTW domain zf-RING_2 PF13639.4 001153466.2_53723001_2 - 1.1e-12 47.9 7.8 1.1e-12 47.9 7.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.3 001153466.2_53723001_2 - 1.6e-12 46.7 1.7 5.4e-12 45.1 1.7 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001153466.2_53723001_2 - 7.2e-06 25.6 7.6 7.2e-06 25.6 7.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001153466.2_53723001_2 - 8.3e-06 25.9 8.5 8.3e-06 25.9 8.5 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001153466.2_53723001_2 - 8.9e-05 22.2 5.9 8.9e-05 22.2 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001153466.2_53723001_2 - 0.0001 22.2 1.6 0.00021 21.1 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.4 001153466.2_53723001_2 - 0.00068 19.4 4.5 0.00068 19.4 4.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001153466.2_53723001_2 - 0.0018 18.1 7.0 0.0067 16.3 7.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.4 001153466.2_53723001_2 - 0.0045 16.7 5.8 0.0045 16.7 5.8 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.6 001153466.2_53723001_2 - 0.011 15.7 2.9 0.051 13.6 2.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.4 001153466.2_53723001_2 - 0.014 15.1 4.7 0.014 15.1 4.7 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TRIQK PF15168.4 001153466.2_53723001_2 - 0.024 14.4 0.1 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Prok-RING_1 PF14446.4 001153466.2_53723001_2 - 0.11 12.3 10.0 0.033 14.0 5.3 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.3 001153466.2_53723001_2 - 1.6 8.3 11.5 0.064 12.7 4.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Auxin_inducible PF02519.12 001153394.2_53722001_2 - 1.7e-18 66.5 0.0 4e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 Auxin responsive protein DDE_Tnp_4 PF13359.4 001153403.2_53724001_2 - 1.8e-40 138.1 0.0 2.6e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.12 001153403.2_53724001_2 - 5.8e-05 22.6 0.0 0.00052 19.5 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein VHP PF02209.17 001153403.2_53724001_2 - 0.12 12.4 0.4 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Villin headpiece domain DIOX_N PF14226.4 001357949.1_53723001_2 - 1.2e-30 106.6 0.0 1.8e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.18 001357949.1_53723001_2 - 1.5e-25 89.5 0.0 3.1e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ald_Xan_dh_C PF01315.20 001357949.1_53723001_2 - 0.19 12.0 1.0 0.73 10.1 0.8 2.1 2 0 0 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain IPK PF03770.14 001349000.1_48624001_1 - 7.7e-48 162.8 0.0 1.1e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase AC_N PF16214.3 001319736.2_53723001_3 - 5.1 6.0 5.3 2.4 7.1 3.4 1.4 1 1 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region LRR_8 PF13855.4 151715.1_53723120_3 - 9.6e-08 31.6 6.4 0.0034 17.0 0.3 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.4 151715.1_53723120_3 - 0.013 15.4 4.2 17 5.7 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.5 151715.1_53723120_3 - 0.024 14.9 11.6 0.25 11.7 1.5 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 151715.1_53723120_3 - 0.58 10.7 10.2 26 5.7 0.1 5.5 5 1 1 6 6 6 0 Leucine Rich Repeat Gamma-thionin PF00304.18 001153529.1_53722001_2 - 2e-14 53.4 15.3 2e-14 53.4 15.3 1.9 2 0 0 2 2 2 1 Gamma-thionin family MBOAT PF03062.17 001315923.1_06924001_1 - 3.2e-28 99.0 23.1 3.2e-28 99.0 23.1 2.0 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.4 001315923.1_06924001_1 - 3e-05 24.1 2.7 7.7e-05 22.8 2.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family KNOX1 PF03790.11 001291922.1_48624001_3 - 3.3e-22 77.8 1.0 3.3e-22 77.8 1.0 2.1 2 0 0 2 2 2 1 KNOX1 domain KNOX2 PF03791.11 001291922.1_48624001_3 - 1.5e-21 75.6 0.9 4.3e-21 74.2 0.9 1.8 1 0 0 1 1 1 1 KNOX2 domain Homeobox_KN PF05920.9 001291922.1_48624001_3 - 1.1e-17 63.5 2.8 2.5e-17 62.4 2.8 1.7 1 0 0 1 1 1 1 Homeobox KN domain ELK PF03789.11 001291922.1_48624001_3 - 4.8e-11 42.3 3.8 9.1e-11 41.4 3.8 1.5 1 0 0 1 1 1 1 ELK domain Homeobox PF00046.27 001291922.1_48624001_3 - 4.2e-07 29.6 1.1 1.1e-06 28.2 0.8 1.9 1 1 1 2 2 2 1 Homeobox domain DUF4228 PF14009.4 001149201.2_53722001_3 - 1.4e-21 77.6 0.1 1.6e-21 77.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) DUF296 PF03479.13 001358085.1_53725001_3 - 2.3e-31 108.1 0.8 3.3e-31 107.6 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF296) AT_hook PF02178.17 001358085.1_53725001_3 - 4.9 7.3 20.1 0.45 10.4 5.2 2.7 2 0 0 2 2 2 0 AT hook motif PRMT5 PF05185.14 001147940.2_53725001_2 - 5.4e-05 22.3 0.0 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.4 001147940.2_53725001_2 - 0.021 15.4 0.0 0.047 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.12 001147940.2_53725001_2 - 0.039 13.4 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.11 001147940.2_53725001_2 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TCP PF03634.11 152262.1_53725120_3 - 1.9e-32 112.8 0.2 1.9e-32 112.8 0.2 2.1 2 0 0 2 2 2 1 TCP family transcription factor AAA_18 PF13238.4 001175821.1_53724001_3 - 5.6e-07 30.0 0.0 1.9e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001175821.1_53724001_3 - 7.3e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.4 001175821.1_53724001_3 - 0.0013 18.8 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.16 001175821.1_53724001_3 - 0.007 16.0 0.0 0.021 14.5 0.0 1.7 1 1 0 2 2 2 1 Cytidylate kinase KTI12 PF08433.8 001175821.1_53724001_3 - 0.0097 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 FAP PF07174.9 001175821.1_53724001_3 - 0.021 14.2 8.2 0.032 13.6 8.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Dynamin_N PF00350.21 001175821.1_53724001_3 - 0.029 14.3 1.1 0.69 9.8 1.1 2.4 1 1 0 1 1 1 0 Dynamin family Zeta_toxin PF06414.10 001175821.1_53724001_3 - 0.05 12.8 0.0 0.16 11.1 0.0 1.7 2 1 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.15 001175821.1_53724001_3 - 0.056 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 LVIVD PF08309.9 001175821.1_53724001_3 - 0.091 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 LVIVD repeat Hydin_ADK PF17213.1 001175821.1_53724001_3 - 0.63 10.2 5.0 23 5.1 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain zf-B_box PF00643.22 001148543.1_53724001_2 - 1.5e-12 47.3 10.8 1.3e-07 31.6 1.2 2.4 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.3 001148543.1_53724001_2 - 0.0019 18.3 13.4 0.0029 17.7 2.4 2.4 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF2318 PF10080.7 001148543.1_53724001_2 - 0.69 9.9 10.1 0.25 11.4 1.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) RRM_1 PF00076.20 001157046.1_53722001_2 - 5.2e-19 67.7 0.0 8.7e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.9 001157046.1_53722001_2 - 0.2 11.6 0.1 0.2 11.6 0.1 2.4 2 1 0 2 2 2 0 RNA binding motif MFS_2 PF13347.4 001318624.1_48624001_2 - 2e-11 42.9 12.3 2e-11 42.9 12.3 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein PUCC PF03209.13 001318624.1_48624001_2 - 8.8e-06 24.8 0.0 8.8e-06 24.8 0.0 2.1 2 1 0 2 2 2 1 PUCC protein SPC12 PF06645.11 001318624.1_48624001_2 - 1.9 8.5 8.3 21 5.2 0.1 4.5 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Myb_DNA-binding PF00249.29 001308508.1_53725001_3 - 7.2e-07 29.1 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain BES1_N PF05687.11 001139162.1_53724001_1 - 1.6e-62 210.3 0.0 3.2e-62 209.3 0.0 1.5 1 0 0 1 1 1 1 BES1/BZR1 plant transcription factor, N-terminal DUF1290 PF06947.10 001358137.1_53724001_3 - 0.055 13.4 0.4 18 5.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1290) Iso_dh PF00180.18 001308493.1_53724001_2 - 1.6e-78 264.1 0.0 2.1e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase tify PF06200.12 001176394.2_53723001_3 - 3.9e-19 67.5 0.0 6.8e-19 66.8 0.0 1.4 1 0 0 1 1 1 1 tify domain CCT_2 PF09425.8 001176394.2_53723001_3 - 6.5e-14 51.4 1.3 1.4e-13 50.3 1.3 1.6 1 0 0 1 1 1 1 Divergent CCT motif Codanin-1_C PF15296.4 001176394.2_53723001_3 - 0.091 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Codanin-1 C-terminus Fasciclin PF02469.20 001348956.1_53723001_1 - 2e-22 79.6 0.1 2.6e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain DEC-1_N PF04625.11 001348956.1_53723001_1 - 0.11 11.4 13.4 0.18 10.7 3.0 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region MEIOC PF15189.4 001348956.1_53723001_3 - 0.11 12.0 0.7 0.19 11.2 0.7 1.3 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC Ran_BP1 PF00638.16 001348981.1_53724001_1 - 1.4e-15 57.4 0.0 2.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.9 001348981.1_53724001_1 - 5.4e-14 52.4 1.6 1.8e-13 50.7 0.1 2.8 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Myb_DNA-bind_4 PF13837.4 001152821.2_53727001_1 - 7.8e-45 151.1 13.3 5.2e-23 81.1 1.5 2.8 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001152821.2_53727001_1 - 1.9e-08 34.3 4.0 0.0021 18.1 0.6 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.7 001152821.2_53727001_1 - 2.6e-07 30.7 10.5 0.00076 19.6 0.4 2.9 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.29 001152821.2_53727001_1 - 6.2e-06 26.1 2.1 0.039 14.0 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.5 001152821.2_53727001_1 - 0.094 13.4 8.7 0.91 10.2 0.3 2.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Methyltransf_16 PF10294.7 001322102.1_53723001_3 - 1.7e-23 83.1 0.0 2.5e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.4 001322102.1_53723001_3 - 0.0084 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Mlo PF03094.13 001320957.1_53724001_3 - 9.6e-148 492.4 6.9 1.2e-147 492.0 6.9 1.0 1 0 0 1 1 1 1 Mlo family DUF2105 PF09878.7 001320957.1_53724001_3 - 0.037 13.6 0.6 0.037 13.6 0.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2105) Myb_DNA-bind_4 PF13837.4 001357861.1_53727001_1 - 8.1e-45 151.0 13.3 5.2e-23 81.1 1.5 2.8 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001357861.1_53727001_1 - 2.4e-08 33.9 4.0 0.0021 18.1 0.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.7 001357861.1_53727001_1 - 2.9e-07 30.6 10.5 0.00076 19.6 0.4 2.7 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.29 001357861.1_53727001_1 - 6.6e-06 26.1 2.1 0.039 14.0 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.5 001357861.1_53727001_1 - 0.087 13.5 8.7 0.92 10.2 0.3 2.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Dabb PF07876.10 001353387.2_53722001_3 - 2.3e-16 60.1 0.0 3.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Chromo PF00385.22 152395.1_53722120_1 - 4e-10 39.3 0.1 6.7e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Complex1_LYR PF05347.13 148497.1_53727120_2 - 2.6e-09 36.8 3.1 4.2e-09 36.2 3.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.4 148497.1_53727120_2 - 0.05 14.2 0.2 0.081 13.5 0.2 1.3 1 0 0 1 1 1 0 Complex1_LYR-like PPR PF01535.18 146596.1_53729120_1 - 5e-37 123.4 2.9 0.00064 19.7 0.0 10.8 10 0 0 10 10 10 8 PPR repeat PPR_2 PF13041.4 146596.1_53729120_1 - 5.7e-36 122.4 0.2 3.4e-09 36.6 0.0 9.1 7 2 3 10 10 10 5 PPR repeat family DYW_deaminase PF14432.4 146596.1_53729120_1 - 1e-25 89.9 0.0 1.6e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases PPR_1 PF12854.5 146596.1_53729120_1 - 1.3e-23 82.3 0.4 0.002 17.7 0.0 8.8 9 1 1 10 10 10 5 PPR repeat PPR_3 PF13812.4 146596.1_53729120_1 - 1.1e-09 38.0 0.0 0.0012 18.8 0.0 4.3 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.2 146596.1_53729120_1 - 3.6e-05 23.1 0.5 0.0098 15.1 0.0 3.4 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PROPR B_lectin PF01453.22 146596.1_53729120_2 - 6.4e-32 109.6 1.4 1.2e-31 108.7 1.4 1.5 1 0 0 1 1 1 1 D-mannose binding lectin S_locus_glycop PF00954.18 146596.1_53729120_2 - 1.8e-21 76.6 1.6 4.4e-21 75.3 1.6 1.6 1 0 0 1 1 1 1 S-locus glycoprotein domain PAN_2 PF08276.9 146596.1_53729120_2 - 1e-15 57.4 2.3 1e-15 57.4 2.3 2.4 2 0 0 2 2 2 1 PAN-like domain Pkinase_Tyr PF07714.15 146596.1_53729120_2 - 2.4e-12 46.6 0.0 1.5e-10 40.7 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.23 146596.1_53729120_2 - 4.4e-12 45.8 0.0 3.1e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase PF00069.23 146596.1_53729120_3 - 1e-20 74.1 0.0 1.5e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 146596.1_53729120_3 - 1.8e-10 40.4 0.0 2.7e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PPR PF01535.18 146597.1_53729120_1 - 3.9e-38 126.9 2.9 0.00051 20.0 0.0 11.1 10 0 0 10 10 10 8 PPR repeat PPR_2 PF13041.4 146597.1_53729120_1 - 6.8e-37 125.3 0.2 2.7e-09 36.9 0.0 9.4 7 2 3 10 10 10 5 PPR repeat family B_lectin PF01453.22 146597.1_53729120_1 - 4.6e-32 110.1 1.4 9.4e-32 109.1 1.4 1.6 1 0 0 1 1 1 1 D-mannose binding lectin DYW_deaminase PF14432.4 146597.1_53729120_1 - 7.1e-26 90.4 0.0 1.2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases PPR_1 PF12854.5 146597.1_53729120_1 - 1.7e-24 85.1 0.4 0.0016 18.0 0.0 9.1 9 1 1 10 10 10 5 PPR repeat S_locus_glycop PF00954.18 146597.1_53729120_1 - 1.9e-21 76.5 3.9 3.4e-21 75.7 1.6 2.4 2 0 0 2 2 2 1 S-locus glycoprotein domain PAN_2 PF08276.9 146597.1_53729120_1 - 8e-16 57.7 2.3 8e-16 57.7 2.3 2.6 2 0 0 2 2 2 1 PAN-like domain Pkinase_Tyr PF07714.15 146597.1_53729120_1 - 1.1e-12 47.7 0.0 1.1e-10 41.1 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.23 146597.1_53729120_1 - 2.7e-12 46.5 0.0 2.4e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain PPR_3 PF13812.4 146597.1_53729120_1 - 4.4e-10 39.4 0.0 0.00092 19.1 0.0 4.6 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.2 146597.1_53729120_1 - 1.5e-05 24.3 0.5 0.0074 15.5 0.0 3.6 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PROPR Pkinase PF00069.23 146597.1_53729120_2 - 7.7e-21 74.5 0.0 1.2e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 146597.1_53729120_2 - 1.4e-10 40.8 0.0 2.1e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 146597.1_53729120_2 - 0.12 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMF_TATA_bd PF12325.6 152386.1_53729120_2 - 0.065 13.3 5.9 0.11 12.6 5.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding EzrA PF06160.10 152388.1_53726120_1 - 0.041 11.9 2.2 0.053 11.6 2.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.6 152388.1_53726120_1 - 0.061 13.4 4.9 0.11 12.5 4.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.20 152388.1_53726120_1 - 0.38 10.9 1.4 11 6.2 1.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.13 152388.1_53726120_1 - 0.85 9.3 2.9 1.4 8.6 2.9 1.2 1 0 0 1 1 1 0 Mnd1 family REPA_OB_2 PF16900.3 152385.1_53724120_2 - 5.7e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Replication protein A OB domain Rep_fac-A_C PF08646.8 152385.1_53724120_2 - 0.0006 19.5 1.6 0.00099 18.7 1.6 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain zf-MYND PF01753.16 152385.1_53724120_2 - 0.6 10.1 4.4 1.7 8.7 4.4 1.8 1 0 0 1 1 1 0 MYND finger MFS_1 PF07690.14 152384.1_53724120_1 - 8e-19 67.6 9.7 8e-19 67.6 9.7 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.22 152384.1_53724120_1 - 1e-12 47.6 3.1 1.5e-12 47.1 3.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.11 152384.1_53724120_1 - 0.0029 16.0 0.8 0.0038 15.6 0.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMF_TATA_bd PF12325.6 152387.1_53729120_3 - 0.068 13.3 6.2 0.11 12.6 6.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.10 152387.1_53729120_3 - 0.79 10.0 4.5 1.4 9.2 4.5 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) EzrA PF06160.10 152389.1_53725120_1 - 0.043 11.9 2.6 0.056 11.5 2.6 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.6 152389.1_53725120_1 - 0.059 13.5 5.1 0.093 12.8 5.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4391 PF14335.4 152389.1_53725120_1 - 0.063 12.8 0.4 0.088 12.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Spc7 PF08317.9 152389.1_53725120_1 - 0.13 11.0 2.7 0.19 10.4 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.10 152389.1_53725120_1 - 0.44 10.8 4.3 0.72 10.1 4.3 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) IncA PF04156.12 152389.1_53725120_1 - 0.87 9.2 4.5 1.3 8.6 4.5 1.2 1 0 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.10 152389.1_53725120_1 - 3 7.8 8.1 9.9 6.1 6.9 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein B3 PF02362.19 001112070.1_53725001_1 - 4.3e-16 58.5 0.0 7.8e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 B3 DNA binding domain PEPcase PF00311.15 001288013.1_48627001_2 - 0 1024.8 0.0 0 1024.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.4 001288013.1_48627001_2 - 0.00073 18.0 0.0 0.0013 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase eIF-5a PF01287.18 001288236.1_48621001_1 - 3.5e-28 97.4 0.6 5.1e-28 96.8 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.10 001288236.1_48621001_1 - 0.0011 18.8 0.1 0.0018 18.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DUF4752 PF15944.3 001288536.1_48622001_2 - 1.5 8.8 5.2 2.7 8.0 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) Kunitz_legume PF00197.16 001288536.1_48622001_3 - 3.8e-36 124.6 0.0 5.1e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin and protease inhibitor HMG-CoA_red PF00368.16 001288532.1_48625001_3 - 9.1e-143 475.6 1.6 1.1e-142 475.3 1.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Kunitz_legume PF00197.16 001288091.1_48622001_1 - 2.7e-35 121.8 0.0 3.5e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor Mito_carr PF00153.25 001288561.1_48623001_1 - 1.7e-66 220.0 3.3 1.9e-23 82.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein eIF-5a PF01287.18 001288531.1_48622001_1 - 1.9e-28 98.2 0.3 2.7e-28 97.7 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.10 001288531.1_48622001_1 - 0.012 15.5 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Bet_v_1 PF00407.17 001288085.1_48622001_2 - 2.6e-37 127.9 0.7 3.2e-37 127.6 0.7 1.1 1 0 0 1 1 1 1 Pathogenesis-related protein Bet v I family Pkinase PF00069.23 001287861.1_48625001_3 - 9e-72 241.5 0.0 1.3e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001287861.1_48625001_3 - 5.7e-33 109.9 9.1 9.2e-08 31.0 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001287861.1_48625001_3 - 1.5e-26 89.9 4.7 4.2e-07 29.3 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001287861.1_48625001_3 - 1.5e-24 86.1 4.5 4.1e-12 46.3 1.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.15 001287861.1_48625001_3 - 4.1e-24 85.1 0.0 6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_5 PF13202.4 001287861.1_48625001_3 - 2e-22 77.5 6.8 9.6e-06 24.8 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001287861.1_48625001_3 - 2.1e-19 68.9 14.8 3.7e-08 32.9 0.6 5.2 2 1 3 5 5 5 4 EF-hand domain pair EF-hand_4 PF12763.5 001287861.1_48625001_3 - 5.1e-07 29.5 0.8 0.0024 17.6 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001287861.1_48625001_3 - 8.1e-06 25.9 0.8 0.014 15.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.12 001287861.1_48625001_3 - 0.00013 21.3 0.1 0.00024 20.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA_synt_1c_R1 PF04558.13 001287861.1_48625001_3 - 0.0055 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 SPARC_Ca_bdg PF10591.7 001287861.1_48625001_3 - 0.0058 16.8 0.2 3.1 8.0 0.2 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001287861.1_48625001_3 - 0.013 16.2 0.1 1.3 9.9 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain APH PF01636.21 001287861.1_48625001_3 - 0.017 14.9 0.1 2.5 7.8 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF374 PF04028.11 001287861.1_48625001_3 - 0.063 12.7 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Sucrose_synth PF00862.17 001288357.1_48625001_3 - 2.1e-277 920.7 0.0 3e-277 920.2 0.0 1.2 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001288357.1_48625001_3 - 5.2e-35 120.4 0.0 1.6e-34 118.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001288357.1_48625001_3 - 6.7e-12 45.8 0.0 2.1e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001288357.1_48625001_3 - 5.9e-05 23.3 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_CodY PF08222.9 001288357.1_48625001_3 - 0.045 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 CodY helix-turn-helix domain Kunitz_legume PF00197.16 001288498.1_48622001_3 - 8e-36 123.5 0.0 9.5e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor DUF1618 PF07762.12 001288206.1_48622001_1 - 0.081 13.9 0.4 0.13 13.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1618) TOM20_plant PF06552.10 001288206.1_48622001_3 - 5.9e-103 342.3 0.3 6.9e-103 342.1 0.3 1.0 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.4 001288206.1_48622001_3 - 0.00015 21.2 0.0 0.14 11.8 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.26 001288206.1_48622001_3 - 0.11 12.2 0.5 1.9 8.3 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.15 001288206.1_48622001_3 - 0.13 12.3 1.8 2.8 8.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.21 001288394.1_48622001_2 - 5.9e-34 115.5 0.4 9.6e-34 114.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.17 001288394.1_48622001_2 - 1.7e-27 95.2 2.4 3.4e-27 94.2 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.6 001288394.1_48622001_2 - 6.6e-16 57.8 0.6 6.6e-16 57.8 0.6 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001288394.1_48622001_2 - 6e-05 23.3 0.2 0.00035 20.8 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.4 001288394.1_48622001_2 - 0.00074 19.5 0.4 0.0015 18.5 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001288394.1_48622001_2 - 0.014 15.8 0.5 0.022 15.2 0.5 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Chal_sti_synt_N PF00195.17 001288367.1_48623001_1 - 1.6e-124 413.5 0.1 2.3e-124 413.0 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.13 001288367.1_48623001_1 - 2.2e-72 241.8 0.0 3.7e-72 241.1 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.8 001288367.1_48623001_1 - 3.1e-07 30.3 0.1 2.9e-06 27.2 0.0 2.5 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.8 001288367.1_48623001_1 - 1.1e-06 28.3 0.0 6.1e-06 25.9 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.10 001288367.1_48623001_1 - 1.2e-06 28.0 0.0 1.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein FMN_red PF03358.13 001288523.1_48622001_1 - 3.2e-38 130.8 0.0 4.7e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.15 001288523.1_48622001_1 - 1.3e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold DUF4604 PF15377.4 001288523.1_48622001_1 - 0.012 15.9 12.5 0.017 15.4 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Chal_sti_synt_N PF00195.17 001288423.1_48623001_1 - 6e-125 414.9 0.0 9.1e-125 414.3 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.13 001288423.1_48623001_1 - 6.6e-71 237.1 0.0 1.2e-70 236.2 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.8 001288423.1_48623001_1 - 3e-06 27.2 0.1 1.8e-05 24.7 0.1 2.3 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.8 001288423.1_48623001_1 - 8.1e-06 25.5 0.0 0.00019 21.1 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.10 001288423.1_48623001_1 - 9.7e-06 24.9 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein eIF-5a PF01287.18 001288030.1_48622001_2 - 6.4e-28 96.5 0.2 1e-27 95.9 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.10 001288030.1_48622001_2 - 0.017 15.0 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain TCTP PF00838.15 001288253.1_48622001_1 - 4.9e-55 186.2 0.1 6.1e-55 185.9 0.1 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein Pkinase PF00069.23 001287877.1_48625001_2 - 4.6e-74 249.0 0.0 6.2e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001287877.1_48625001_2 - 3.4e-32 107.4 6.1 1.7e-07 30.2 0.8 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001287877.1_48625001_2 - 2.2e-26 89.4 1.8 1.5e-06 27.6 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001287877.1_48625001_2 - 2.2e-25 88.8 3.0 4.9e-12 46.0 1.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.15 001287877.1_48625001_2 - 2.2e-24 86.0 0.0 3.2e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_5 PF13202.4 001287877.1_48625001_2 - 8e-21 72.4 5.4 8.9e-05 21.7 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001287877.1_48625001_2 - 3.1e-20 71.6 14.0 1.7e-08 33.9 0.1 5.1 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_4 PF12763.5 001287877.1_48625001_2 - 6.6e-08 32.3 0.3 0.0016 18.3 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001287877.1_48625001_2 - 1.8e-05 24.8 0.9 0.01 16.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.12 001287877.1_48625001_2 - 5.3e-05 22.5 0.1 0.0001 21.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_11 PF08976.9 001287877.1_48625001_2 - 0.013 16.2 0.0 1.7 9.4 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain DUF374 PF04028.11 001287877.1_48625001_2 - 0.026 14.0 0.0 0.073 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF374) tRNA_synt_1c_R1 PF04558.13 001287877.1_48625001_2 - 0.027 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 SPARC_Ca_bdg PF10591.7 001287877.1_48625001_2 - 0.028 14.6 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.21 001287877.1_48625001_2 - 0.038 13.8 0.0 3.5 7.3 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family EF-hand_10 PF14788.4 001287877.1_48625001_2 - 0.048 13.4 1.0 1.5 8.7 0.3 2.7 2 0 0 2 2 2 0 EF hand Kinase-like PF14531.4 001287877.1_48625001_2 - 0.049 12.8 0.1 0.81 8.8 0.2 2.5 1 1 1 2 2 2 0 Kinase-like Bet_v_1 PF00407.17 001287893.1_48622001_2 - 6.8e-38 129.8 0.5 8.1e-38 129.6 0.5 1.1 1 0 0 1 1 1 1 Pathogenesis-related protein Bet v I family SNAP PF14938.4 001288116.1_48623001_2 - 5.8e-107 357.2 9.1 6.6e-107 357.0 9.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.4 001288116.1_48623001_2 - 7.3e-07 29.3 8.6 0.0017 18.5 0.7 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.15 001288116.1_48623001_2 - 0.00046 20.0 18.7 4.3 7.6 1.3 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat NSF PF02071.18 001288116.1_48623001_2 - 0.0011 19.1 20.6 4.6 8.3 0.0 7.5 7 1 1 8 8 7 1 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.4 001288116.1_48623001_2 - 0.0019 18.0 6.9 6.8 6.8 0.4 5.4 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.4 001288116.1_48623001_2 - 0.0047 17.3 6.2 48 4.8 0.2 5.7 4 1 3 7 7 6 0 Tetratricopeptide repeat Gin PF10764.7 001288116.1_48623001_2 - 0.022 14.6 0.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin TPR_8 PF13181.4 001288116.1_48623001_2 - 0.094 12.9 16.6 4.5 7.6 0.4 5.8 4 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.4 001288116.1_48623001_2 - 0.12 13.1 7.5 12 6.9 0.3 5.2 4 2 3 7 7 7 0 Tetratricopeptide repeat DHR-2 PF06920.11 001288116.1_48623001_2 - 0.12 10.8 3.4 0.11 11.0 1.0 2.0 2 1 0 2 2 2 0 Dock homology region 2 TPR_19 PF14559.4 001288116.1_48623001_2 - 0.28 11.6 9.6 7.2 7.1 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.26 001288116.1_48623001_2 - 3.6 7.4 25.7 3.1 7.7 1.7 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat RibD_C PF01872.15 001279545.1_53724001_1 - 4.8e-41 140.7 0.0 7e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain DUF1768 PF08719.9 001279545.1_53724001_1 - 1.5e-33 116.2 0.0 2.2e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Glyco_hydro_79n PF03662.12 001279545.1_53724001_1 - 0.024 13.4 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain HMG-CoA_red PF00368.16 001288011.1_48625001_2 - 3.3e-143 477.0 1.9 4e-143 476.7 1.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase eIF-5a PF01287.18 001288153.1_48622001_1 - 7.6e-29 99.5 0.2 1.3e-28 98.8 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.10 001288153.1_48622001_1 - 0.0062 16.4 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain HMG-CoA_red PF00368.16 001288473.1_48625001_3 - 1.5e-143 478.2 4.0 1.8e-143 477.9 4.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Pkinase PF00069.23 001316271.1_06924001_2 - 9.9e-64 215.1 0.0 1.2e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316271.1_06924001_2 - 3.2e-25 88.8 0.0 4.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.18 001316271.1_06924001_2 - 0.0018 17.8 0.1 0.0028 17.2 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.4 001316271.1_06924001_2 - 0.015 14.5 0.3 3.5 6.7 0.1 2.3 1 1 1 2 2 2 0 Kinase-like APH PF01636.21 001316271.1_06924001_2 - 0.016 15.0 0.2 0.055 13.3 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.12 001316271.1_06924001_2 - 0.086 12.0 0.3 0.14 11.4 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HAUS6_N PF14661.4 001316271.1_06924001_3 - 0.04 13.4 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AdoMetDC_leader PF08132.9 001319859.1_48624001_2 - 4.2e-08 32.9 0.7 4.2e-08 32.9 0.7 1.9 2 0 0 2 2 2 1 S-adenosyl-l-methionine decarboxylase leader peptide SAM_decarbox PF01536.14 001319859.1_48624001_3 - 8e-106 353.9 0.0 1e-105 353.5 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase HSP70 PF00012.18 001318560.1_48625001_3 - 4.8e-261 867.1 7.8 5.5e-261 866.9 7.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001318560.1_48625001_3 - 6.4e-14 51.4 4.1 8.2e-12 44.4 0.1 2.9 3 1 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.4 001318560.1_48625001_3 - 0.00015 22.0 4.6 0.89 9.9 0.0 3.8 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.14 001318560.1_48625001_3 - 0.00095 18.8 0.0 0.0042 16.7 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Dynamin_M PF01031.18 001318560.1_48625001_3 - 0.022 13.9 0.1 0.063 12.4 0.0 1.8 2 0 0 2 2 2 0 Dynamin central region Cupin_1 PF00190.20 001315795.1_06922001_3 - 1.4e-34 118.7 0.4 1.9e-34 118.3 0.4 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.9 001315795.1_06922001_3 - 7.4e-11 41.5 0.0 1.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.10 001315795.1_06922001_3 - 0.08 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_7 PF12973.5 001315795.1_06922001_3 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain Ribosomal_S2 PF00318.18 001315694.1_06923001_1 - 8.9e-26 90.3 0.1 5.2e-12 45.3 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.3 001315694.1_06923001_1 - 0.08 14.2 13.0 0.16 13.3 13.0 1.5 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus Oleosin PF01277.15 001315713.1_06922001_3 - 5.2e-22 77.6 7.5 7e-22 77.2 7.5 1.2 1 0 0 1 1 1 1 Oleosin MSP PF01716.16 001318542.1_48622001_1 - 3.4e-64 216.2 0.5 1e-62 211.4 0.5 2.1 1 1 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide Sucrose_synth PF00862.17 001347883.1_53726001_3 - 3.4e-285 946.4 0.0 4.2e-285 946.1 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001347883.1_53726001_3 - 7.9e-34 116.6 0.0 1.2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001347883.1_53726001_3 - 8.4e-11 42.3 0.0 1.6e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001347883.1_53726001_3 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 RIO1 PF01163.20 001308376.1_53724001_2 - 8e-51 172.2 0.7 1.3e-50 171.4 0.1 1.7 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.9 001308376.1_53724001_2 - 2.8e-35 120.3 0.6 4.8e-35 119.5 0.6 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.21 001308376.1_53724001_2 - 8.3e-10 38.9 1.5 8.6e-06 25.7 0.2 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.12 001308376.1_53724001_2 - 4.5e-05 22.8 1.1 0.25 10.5 0.0 2.7 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.23 001308376.1_53724001_2 - 0.012 14.9 1.4 0.054 12.7 1.4 1.9 1 1 0 1 1 1 0 Protein kinase domain Pec_lyase_C PF00544.17 001154081.2_53725001_3 - 6.1e-22 78.1 5.6 2.7e-21 76.0 5.6 1.8 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.4 001154081.2_53725001_3 - 4.2e-06 26.6 2.7 9e-06 25.5 2.7 1.6 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.11 001154081.2_53725001_3 - 0.045 12.9 0.2 0.071 12.2 0.2 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) RCDG1 PF15725.3 001154081.2_53725001_3 - 4.7 7.6 10.0 0.095 13.0 2.5 2.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Nsp1_C PF05064.11 001175489.2_53726001_1 - 2.1e-20 72.5 3.3 2.1e-20 72.5 3.3 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.4 001175489.2_53726001_1 - 1.8e-05 25.4 23.9 1.8e-05 25.4 23.9 7.3 1 1 4 5 5 3 1 Nucleoporin FG repeat region Flagellar_rod PF05149.10 001175489.2_53726001_1 - 0.046 13.0 9.3 0.068 12.5 9.3 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein NAP PF00956.16 001175489.2_53726001_1 - 0.067 12.2 0.2 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Nbl1_Borealin_N PF10444.7 001175489.2_53726001_1 - 0.13 11.8 7.9 2 8.0 0.0 3.3 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal APG6 PF04111.10 001175489.2_53726001_1 - 0.29 10.4 12.5 0.42 9.8 12.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Sec34 PF04136.13 001175489.2_53726001_1 - 0.32 10.7 2.8 0.57 9.9 2.8 1.4 1 0 0 1 1 1 0 Sec34-like family UPF0242 PF06785.9 001175489.2_53726001_1 - 0.93 8.0 5.1 1.8 7.1 5.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF16 PF01519.14 001175489.2_53726001_1 - 4.9 7.5 5.2 16 5.9 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF724 PF05266.12 001175489.2_53726001_1 - 5.3 6.7 7.8 2.4 7.8 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.10 001175489.2_53726001_1 - 8.2 6.3 8.4 25 4.7 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RIO1 PF01163.20 001143624.2_53724001_3 - 1.4e-50 171.4 0.1 1.4e-50 171.4 0.1 1.9 2 1 1 3 3 3 1 RIO1 family Rio2_N PF09202.9 001143624.2_53724001_3 - 2.7e-35 120.3 0.6 4.8e-35 119.5 0.6 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.21 001143624.2_53724001_3 - 2.7e-09 37.2 3.9 8.9e-06 25.7 0.3 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.12 001143624.2_53724001_3 - 4.1e-05 22.9 1.2 0.25 10.5 0.0 2.8 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.23 001143624.2_53724001_3 - 0.012 14.9 1.4 0.054 12.7 1.4 2.0 1 1 0 1 1 1 0 Protein kinase domain YABBY PF04690.11 001155258.1_53723001_2 - 2.3e-47 161.4 7.3 5.8e-47 160.1 7.3 1.6 1 1 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.8 001155258.1_53723001_2 - 0.0011 19.4 0.5 0.0018 18.7 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.17 001155258.1_53723001_2 - 0.0041 17.4 0.2 0.0066 16.7 0.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box DUF1014 PF06244.10 001155258.1_53723001_2 - 0.11 13.0 0.1 0.17 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) Mu-like_Com PF10122.7 001155258.1_53723001_2 - 0.61 9.4 4.4 0.6 9.5 1.5 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com Pkinase PF00069.23 001358523.1_53724001_1 - 7.4e-50 169.6 0.0 1.1e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001358523.1_53724001_1 - 2.1e-19 69.7 0.0 5e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001358523.1_53724001_1 - 0.0044 16.3 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.26 001358547.1_53728001_3 - 7.5e-33 114.6 0.3 1.3e-32 113.9 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_4 PF13418.4 001358547.1_53728001_3 - 1.1e-21 76.4 5.2 3.8e-05 23.4 0.0 6.8 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.4 001358547.1_53728001_3 - 5.2e-21 74.3 11.1 3.3e-05 23.9 0.0 8.2 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.13 001358547.1_53728001_3 - 2.7e-17 61.8 1.9 1.9e-05 24.3 0.0 6.8 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.23 001358547.1_53728001_3 - 8.4e-17 60.4 1.2 0.00091 18.6 0.2 6.8 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.4 001358547.1_53728001_3 - 8.6e-16 57.4 9.6 0.011 15.5 0.0 6.8 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.4 001358547.1_53728001_3 - 1.8e-10 40.6 1.2 0.042 14.0 0.0 6.1 5 1 1 6 6 6 3 Kelch motif STPPase_N PF16891.3 001358547.1_53728001_3 - 1.4e-05 25.3 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain MARVEL PF01284.21 001358547.1_53728001_3 - 0.05 13.5 6.5 0.02 14.8 3.5 1.8 2 0 0 2 2 2 0 Membrane-associating domain Peptidase_C12 PF01088.19 152418.1_53723120_1 - 2.3e-50 171.2 0.0 7.8e-35 120.4 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 TPT PF03151.14 152417.1_53724120_2 - 3.9e-09 36.1 9.3 5.4e-09 35.7 9.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.18 152417.1_53724120_2 - 0.53 10.3 23.2 0.11 12.5 16.9 2.5 2 1 0 2 2 2 0 EamA-like transporter family DRMBL PF07522.12 152422.1_53724120_2 - 1.5e-34 118.5 0.0 2.4e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.5 152422.1_53724120_2 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.25 152422.1_53724120_2 - 0.031 14.1 2.7 0.081 12.8 2.7 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RMMBL PF07521.10 152422.1_53724120_2 - 0.11 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Pkinase PF00069.23 001358585.1_53729001_3 - 9.1e-41 139.8 0.0 1.2e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001358585.1_53729001_3 - 3.8e-40 137.7 0.0 5.1e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.20 001358608.1_53723001_1 - 1.6e-58 196.8 0.1 2e-58 196.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001358608.1_53723001_1 - 1.9e-34 118.4 0.1 2.6e-34 117.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001358608.1_53723001_1 - 1.8e-13 50.2 0.0 2.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001358608.1_53723001_1 - 2.3e-05 24.3 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001358608.1_53723001_1 - 0.00087 19.1 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001358608.1_53723001_1 - 0.0039 16.4 0.0 0.005 16.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.4 001358608.1_53723001_1 - 0.0056 16.9 0.0 0.0092 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 001358608.1_53723001_1 - 0.023 14.8 0.0 0.097 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.25 001358608.1_53723001_1 - 0.056 12.8 0.1 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001358608.1_53723001_1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.25 001358608.1_53723001_1 - 0.19 12.1 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter 2-Hacid_dh_C PF02826.17 001287898.1_48623001_3 - 2.5e-52 176.6 0.0 3.6e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.28 001287898.1_48623001_3 - 1.4e-15 57.0 0.0 2.7e-15 56.1 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.13 001287898.1_48623001_3 - 0.00062 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.18 001287898.1_48623001_3 - 0.0098 15.8 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_C PF03720.13 001287898.1_48623001_3 - 0.019 15.2 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain GFO_IDH_MocA PF01408.20 001287898.1_48623001_3 - 0.052 14.2 0.0 0.29 11.8 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold RGP PF03214.11 001288345.1_48623001_3 - 3.3e-179 595.2 0.0 3.8e-179 595.0 0.0 1.0 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide Glyco_tranf_2_2 PF10111.7 001288345.1_48623001_3 - 0.086 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.24 001288345.1_48623001_3 - 0.12 12.0 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 RGP PF03214.11 001288097.1_48623001_1 - 2e-177 589.4 0.0 2.3e-177 589.2 0.0 1.0 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide Glyco_tranf_2_2 PF10111.7 001288097.1_48623001_1 - 0.06 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.24 001288097.1_48623001_1 - 0.089 12.5 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 PNP_UDP_1 PF01048.18 001358645.1_53723001_3 - 3.6e-22 78.6 0.1 5e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily CG-1 PF03859.14 001358648.1_53728001_1 - 3.8e-47 158.8 0.3 1e-46 157.3 0.3 1.8 1 0 0 1 1 1 1 CG-1 domain Ank_2 PF12796.5 001358648.1_53728001_1 - 3.3e-11 43.5 0.0 3.4e-06 27.4 0.0 2.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) IQ PF00612.25 001358648.1_53728001_1 - 4.8e-09 35.1 17.8 3.1e-05 23.3 2.5 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif TIG PF01833.22 001358648.1_53728001_1 - 5.5e-07 29.5 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 IPT/TIG domain Ank_4 PF13637.4 001358648.1_53728001_1 - 3.1e-06 27.5 0.0 9.2e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.28 001358648.1_53728001_1 - 2.3e-05 24.5 0.0 0.00024 21.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.4 001358648.1_53728001_1 - 0.0006 19.9 0.0 0.0035 17.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat W2 PF02020.16 001358648.1_53728001_1 - 0.0043 17.0 1.6 0.0088 16.0 0.1 2.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Ank_5 PF13857.4 001358648.1_53728001_1 - 0.062 13.6 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF707 PF05212.10 001358682.1_53724001_3 - 1.8e-124 414.7 0.0 2.5e-124 414.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF707) F-box-like PF12937.5 001358690.1_53726001_1 - 3e-06 26.9 0.1 1.1e-05 25.0 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001358690.1_53726001_1 - 2.6e-05 23.8 0.2 7.2e-05 22.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.4 001358690.1_53726001_1 - 0.13 12.3 0.4 0.52 10.4 0.1 2.3 2 0 0 2 2 2 0 Leucine Rich repeat DUF702 PF05142.10 001136776.1_53724001_2 - 2.8e-64 216.0 6.5 3.9e-64 215.5 6.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF702) PBD PF00786.26 144528.1_53724120_1 - 0.00015 22.0 0.1 0.00029 21.0 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Ribosomal_S9 PF00380.17 152383.1_53728120_1 - 0.0016 18.8 0.1 0.004 17.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Atrophin-1 PF03154.13 152383.1_53728120_1 - 0.016 13.4 9.4 0.023 12.9 9.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 152383.1_53728120_1 - 0.24 11.3 8.9 0.43 10.4 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FAM27 PF15832.3 152383.1_53728120_1 - 0.57 10.6 7.0 1.1 9.7 7.0 1.4 1 0 0 1 1 1 0 FAM27 D and E protein family Rrn6 PF10214.7 152383.1_53728120_1 - 1.7 6.9 8.8 2.4 6.3 8.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Atrophin-1 PF03154.13 152383.1_53728120_2 - 0.00022 19.6 5.8 0.00022 19.6 5.8 1.6 2 0 0 2 2 2 1 Atrophin-1 family DUF3915 PF13054.4 152383.1_53728120_2 - 0.00099 18.9 5.8 0.0021 17.9 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) DUF4283 PF14111.4 152383.1_53728120_3 - 1.8e-06 27.4 0.1 3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4283) DUF3915 PF13054.4 152383.1_53728120_3 - 0.0018 18.1 1.6 0.0039 17.0 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 152383.1_53728120_3 - 0.004 15.4 5.8 0.0064 14.7 5.8 1.2 1 0 0 1 1 1 1 Atrophin-1 family FAM27 PF15832.3 152383.1_53728120_3 - 2.3 8.7 6.0 6.3 7.3 6.0 1.6 1 0 0 1 1 1 0 FAM27 D and E protein family RINGv PF12906.5 001358731.1_53722001_3 - 1.7e-09 37.5 4.9 3.8e-09 36.4 4.9 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.9 001358731.1_53722001_3 - 0.053 13.7 3.6 0.06 13.5 1.4 2.3 2 0 0 2 2 2 0 RING-like domain zf-RING_2 PF13639.4 001358731.1_53722001_3 - 0.1 12.8 2.6 0.32 11.2 2.6 2.0 1 0 0 1 1 1 0 Ring finger domain WD40 PF00400.30 001358829.1_53726001_2 - 1.3e-57 190.3 36.2 5.1e-07 30.2 0.1 11.2 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.9 001358829.1_53726001_2 - 4.9e-44 149.5 0.0 8.1e-44 148.8 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.5 001358829.1_53726001_2 - 1.8e-12 47.3 3.7 0.36 11.0 0.0 7.8 3 3 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 001358829.1_53726001_2 - 1.6e-09 36.8 7.4 0.01 14.3 0.0 6.6 5 1 1 7 7 7 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.3 001358829.1_53726001_2 - 7.6e-06 25.0 9.1 0.045 12.6 0.5 5.4 2 2 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.3 001358829.1_53726001_2 - 0.00049 19.4 0.1 0.071 12.3 0.0 3.8 5 1 0 5 5 5 1 WD40-like domain Nucleoporin_N PF08801.9 001358829.1_53726001_2 - 0.001 17.8 0.0 2.8 6.5 0.0 4.1 2 2 2 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.14 001358829.1_53726001_2 - 0.015 13.7 0.1 0.12 10.7 0.0 2.5 3 1 1 4 4 4 0 Cytochrome D1 heme domain Hira PF07569.9 001358829.1_53726001_2 - 0.051 13.2 3.0 11 5.5 0.0 4.4 5 0 0 5 5 5 0 TUP1-like enhancer of split Rax2 PF12768.5 001358829.1_53726001_2 - 0.077 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Cortical protein marker for cell polarity PEPCK_ATP PF01293.18 152514.1_53722120_1 - 1.5e-25 89.7 0.0 1.9e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Herpes_HEPA PF03324.12 152514.1_53722120_1 - 0.1 12.9 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein RRM_2 PF04059.10 001358859.1_53729001_1 - 1.2e-54 182.4 0.8 1.9e-54 181.7 0.8 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.20 001358859.1_53729001_1 - 6.1e-26 89.9 0.2 6e-10 38.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001358859.1_53729001_1 - 1.2e-06 28.0 0.0 0.0015 18.0 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001358859.1_53729001_1 - 1.6e-06 27.7 0.0 0.0086 15.8 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Smg4_UPF3 PF03467.13 001358859.1_53729001_1 - 0.004 17.1 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 Smg-4/UPF3 family BRAP2 PF07576.10 001358859.1_53729001_1 - 0.0062 16.6 0.0 0.039 14.0 0.0 2.0 2 0 0 2 2 2 1 BRCA1-associated protein 2 ACC_central PF08326.10 001358855.1_53729001_3 - 5.6e-196 652.8 3.0 7.1e-196 652.5 3.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.20 001358855.1_53729001_3 - 1.6e-165 551.4 0.0 2.2e-165 550.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.15 001358855.1_53729001_3 - 3.9e-47 160.3 0.1 6.9e-47 159.5 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.20 001358855.1_53729001_3 - 3.2e-31 108.0 0.0 6.7e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.17 001358855.1_53729001_3 - 1.5e-22 79.6 0.0 5.5e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.20 001358855.1_53729001_3 - 3.6e-10 39.4 0.0 7.8e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.12 001358855.1_53729001_3 - 1.9e-09 37.6 0.4 2.5e-08 34.0 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain ATP-grasp PF02222.20 001358855.1_53729001_3 - 3.6e-06 26.5 0.1 7.6e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.11 001358855.1_53729001_3 - 3.3e-05 23.4 0.0 0.00011 21.7 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus NAD_binding_1 PF00175.19 152520.1_53722120_2 - 6.1e-19 68.5 0.1 8.7e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3854 PF12965.5 152520.1_53722120_2 - 0.077 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) ABC_tran PF00005.25 001174857.2_53725001_2 - 5.8e-50 169.2 0.5 1.8e-24 86.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.4 001174857.2_53725001_2 - 1.9e-20 73.8 8.5 1.1e-05 25.3 0.1 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.17 001174857.2_53725001_2 - 1.6e-12 47.2 0.2 0.00032 20.1 0.0 3.5 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.14 001174857.2_53725001_2 - 1.5e-08 34.6 0.0 0.00025 20.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.4 001174857.2_53725001_2 - 3.5e-08 32.9 0.1 0.0017 17.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.4 001174857.2_53725001_2 - 8.6e-08 32.8 2.5 0.0012 19.3 0.0 3.2 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.4 001174857.2_53725001_2 - 5.3e-07 29.9 0.7 0.028 14.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.21 001174857.2_53725001_2 - 8.9e-06 25.7 0.0 0.0089 16.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.4 001174857.2_53725001_2 - 1.6e-05 25.2 4.9 0.075 13.3 0.1 3.1 4 0 0 4 4 2 2 AAA ATPase domain AAA PF00004.27 001174857.2_53725001_2 - 1.9e-05 25.0 0.0 0.51 10.6 0.0 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 001174857.2_53725001_2 - 0.00021 21.4 0.2 1 9.5 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.4 001174857.2_53725001_2 - 0.0004 20.0 6.8 0.16 11.4 0.1 3.6 4 0 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.20 001174857.2_53725001_2 - 0.00046 20.4 0.1 0.54 10.5 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.4 001174857.2_53725001_2 - 0.00049 20.1 0.0 1.7 8.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.4 001174857.2_53725001_2 - 0.00056 19.6 0.0 0.32 10.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.4 001174857.2_53725001_2 - 0.00062 20.1 0.0 1.4 9.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.4 001174857.2_53725001_2 - 0.0007 19.2 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.4 001174857.2_53725001_2 - 0.002 17.6 3.8 0.14 11.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain Dynamin_N PF00350.21 001174857.2_53725001_2 - 0.0028 17.6 0.1 0.22 11.4 0.0 3.2 2 1 1 3 3 3 1 Dynamin family DUF87 PF01935.15 001174857.2_53725001_2 - 0.0032 17.4 0.3 4.2 7.2 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF87 NACHT PF05729.10 001174857.2_53725001_2 - 0.0032 17.3 0.1 2.5 7.9 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.4 001174857.2_53725001_2 - 0.0063 16.4 0.0 5.5 6.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain cobW PF02492.17 001174857.2_53725001_2 - 0.0065 15.9 0.1 2.7 7.4 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran_Xtn PF12848.5 001174857.2_53725001_2 - 0.007 16.2 4.8 0.007 16.2 4.8 3.4 4 0 0 4 4 3 1 ABC transporter ArgK PF03308.14 001174857.2_53725001_2 - 0.025 13.4 0.5 1.5 7.6 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.12 001174857.2_53725001_2 - 0.031 14.1 0.1 8.3 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.20 001174857.2_53725001_2 - 0.06 12.8 0.0 9.5 5.7 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.13 001174857.2_53725001_2 - 0.075 12.8 0.0 6.2 6.6 0.0 2.5 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.16 001174857.2_53725001_2 - 0.1 12.2 2.9 1.4 8.5 0.0 3.0 3 0 0 3 3 2 0 Cytidylate kinase AAA_27 PF13514.4 001174857.2_53725001_2 - 0.17 11.3 2.6 1.6 8.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.4 001174857.2_53725001_2 - 0.19 11.8 6.2 3.6 7.8 0.2 4.3 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Myb_DNA-binding PF00249.29 001137160.1_53725001_1 - 3.2e-31 107.1 1.6 4e-15 55.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001137160.1_53725001_1 - 7.8e-20 70.7 0.2 1.5e-13 50.7 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001137160.1_53725001_1 - 0.014 15.3 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 SLIDE Myb_DNA-bind_2 PF08914.9 001137160.1_53725001_1 - 0.14 12.3 0.0 0.86 9.7 0.0 2.2 1 1 1 2 2 2 0 Rap1 Myb domain DUF3774 PF12609.6 001353015.1_53722001_3 - 1e-28 100.0 0.6 1e-28 100.0 0.6 1.9 2 0 0 2 2 2 1 Wound-induced protein DUF1644 PF07800.10 001137844.1_53724001_3 - 3.6e-65 219.0 9.1 6.4e-65 218.2 9.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) tify PF06200.12 148410.1_53722120_2 - 8.3e-19 66.5 0.0 1.5e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 tify domain YGGT PF02325.15 151729.1_53722120_3 - 0.001 19.3 0.3 0.0026 18.0 0.3 1.7 1 0 0 1 1 1 1 YGGT family MHYT PF03707.14 151696.1_53723120_3 - 0.061 13.4 1.3 0.16 12.0 1.3 1.7 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF241 PF03087.12 147450.1_53722120_3 - 0.00029 20.6 0.4 0.38 10.4 0.0 2.2 2 0 0 2 2 2 2 Arabidopsis protein of unknown function PNRC PF15365.4 147609.1_53722120_3 - 2.3 8.7 9.1 5.2 7.6 9.1 1.6 1 1 0 1 1 1 0 Proline-rich nuclear receptor coactivator tRNA-synt_1e PF01406.17 152535.1_53725120_1 - 1e-43 149.7 1.0 1.5e-43 149.1 1.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain CBFB_NFYA PF02045.13 152535.1_53725120_1 - 3.8e-13 49.8 0.0 1.1e-12 48.3 0.0 1.9 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B tRNA-synt_1e PF01406.17 152535.1_53725120_3 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Mito_carr PF00153.25 001111964.1_53724001_3 - 1.2e-68 227.0 2.6 3.3e-24 84.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_60s PF00428.17 001111907.2_53722001_2 - 8.6e-27 93.4 5.3 1.1e-26 93.1 5.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Apolipo_F PF15148.4 001111907.2_53722001_2 - 0.0033 16.8 0.0 0.0044 16.4 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein F Tocopherol_cycl PF14249.4 001111545.1_53724001_1 - 2e-142 474.1 3.6 2.4e-142 473.9 3.6 1.0 1 0 0 1 1 1 1 Tocopherol cyclase Ras PF00071.20 001112608.1_53722001_3 - 3e-62 208.9 0.0 3.7e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001112608.1_53722001_3 - 1e-32 112.8 0.0 1.7e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001112608.1_53722001_3 - 4.5e-12 45.6 0.0 6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001112608.1_53722001_3 - 5.5e-05 23.1 0.0 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001112608.1_53722001_3 - 0.00084 19.1 0.0 0.66 9.7 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001112608.1_53722001_3 - 0.0011 18.4 0.0 0.005 16.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.10 001112608.1_53722001_3 - 0.014 14.6 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.4 001112608.1_53722001_3 - 0.11 12.6 0.1 0.89 9.7 0.0 2.0 1 1 0 2 2 2 0 AAA domain DAP3 PF10236.7 001112608.1_53722001_3 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Remorin_C PF03763.11 001288060.1_48622001_3 - 1.4e-33 114.9 28.1 2.6e-33 114.0 28.1 1.5 1 0 0 1 1 1 1 Remorin, C-terminal region Remorin_N PF03766.11 001288060.1_48622001_3 - 4.8e-17 61.6 13.0 4.8e-17 61.6 13.0 2.6 3 1 0 3 3 3 1 Remorin, N-terminal region KIP1 PF07765.10 001288060.1_48622001_3 - 0.2 11.7 9.5 0.82 9.7 5.1 2.4 1 1 1 2 2 2 0 KIP1-like protein Bap31 PF05529.10 001288060.1_48622001_3 - 1.3 8.4 12.9 2.7 7.4 12.9 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like HpaP PF09483.8 001288060.1_48622001_3 - 6.7 7.0 8.5 8.4 6.7 8.1 1.4 1 1 0 1 1 1 0 Type III secretion protein (HpaP) FBPase PF00316.18 001287913.1_48623001_1 - 2.6e-78 261.8 0.0 5.2e-78 260.8 0.0 1.5 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain Peptidase_M17 PF00883.19 001318637.1_48624001_2 - 3e-113 378.1 1.8 3.9e-113 377.7 1.8 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.15 001318637.1_48624001_2 - 9.7e-26 90.0 0.6 2.4e-25 88.7 0.6 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain EF-hand_1 PF00036.30 001288113.1_48621001_1 - 8.7e-40 131.2 10.7 2.2e-09 36.1 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001288113.1_48621001_1 - 9.3e-34 115.6 4.1 7.2e-18 64.7 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001288113.1_48621001_1 - 3.1e-30 103.6 10.1 5.1e-16 58.0 0.5 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001288113.1_48621001_1 - 3e-28 95.2 6.4 1.8e-09 36.6 0.1 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.4 001288113.1_48621001_1 - 6e-24 82.3 8.8 2.6e-06 26.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001288113.1_48621001_1 - 6.9e-14 51.8 0.2 6.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001288113.1_48621001_1 - 1.9e-09 37.3 1.4 4.1e-05 23.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001288113.1_48621001_1 - 4e-08 33.4 1.3 0.0038 17.4 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001288113.1_48621001_1 - 2.1e-05 25.2 0.1 0.00069 20.3 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.11 001288113.1_48621001_1 - 4.8e-05 23.2 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.11 001288113.1_48621001_1 - 0.00036 20.4 0.5 0.51 10.1 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein EFhand_Ca_insen PF08726.8 001288113.1_48621001_1 - 0.0011 18.9 1.3 0.0046 16.9 0.3 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.14 001288113.1_48621001_1 - 0.0018 18.4 1.9 1.2 9.3 0.4 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb4 GPHH PF16905.3 001288113.1_48621001_1 - 0.0033 17.0 0.0 0.18 11.5 0.0 3.0 3 1 0 3 3 3 1 Voltage-dependent L-type calcium channel, IQ-associated SurA_N_2 PF13623.4 001288113.1_48621001_1 - 0.0037 17.0 1.2 0.87 9.3 0.2 2.2 1 1 1 2 2 2 2 SurA N-terminal domain DUF3349 PF11829.6 001288113.1_48621001_1 - 0.0038 17.9 0.6 4.3 8.0 0.0 2.9 1 1 3 4 4 4 1 Protein of unknown function (DUF3349) TerB PF05099.11 001288113.1_48621001_1 - 0.0048 16.7 0.7 1.3 8.9 0.1 2.4 1 1 1 2 2 2 1 Tellurite resistance protein TerB MotA_activ PF09114.8 001288113.1_48621001_1 - 0.0088 16.0 0.1 0.2 11.7 0.0 2.3 2 1 0 2 2 2 1 Transcription factor MotA, activation domain DUF2267 PF10025.7 001288113.1_48621001_1 - 0.031 14.4 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Fe_hyd_lg_C PF02906.12 001288113.1_48621001_1 - 0.048 13.2 0.7 0.19 11.2 0.7 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Poly_export PF02563.14 001288113.1_48621001_1 - 0.053 13.6 0.0 1.2 9.3 0.0 2.8 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein DUF5132 PF17195.2 001288113.1_48621001_1 - 0.057 13.4 1.1 4.4 7.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) PhageMin_Tail PF10145.7 001288113.1_48621001_1 - 0.074 12.8 0.5 0.15 11.8 0.2 1.6 2 0 0 2 2 2 0 Phage-related minor tail protein YtzH PF14165.4 001288113.1_48621001_1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.7 1 1 0 2 2 1 0 YtzH-like protein Iso_dh PF00180.18 001318618.1_48623001_2 - 3.2e-99 332.2 0.0 3.9e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.5 001318618.1_48623001_2 - 0.1 12.6 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Yippee-Mis18 PF03226.12 001287902.1_48622001_1 - 2.2e-14 53.4 2.1 3.5e-14 52.7 2.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RNA_pol_N PF01194.15 001287902.1_48622001_1 - 0.013 15.6 0.1 0.041 14.1 0.1 1.9 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Jas PF16135.3 001287902.1_48622001_1 - 0.36 10.9 5.8 0.12 12.5 1.1 2.2 1 1 1 2 2 2 0 TPL-binding domain in jasmonate signalling Desulfoferrod_N PF06397.10 001287902.1_48622001_1 - 1 8.9 5.5 2 8.0 0.0 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain CTP_transf_1 PF01148.18 001288218.1_48625001_1 - 1.6e-88 296.8 21.6 2.4e-88 296.2 21.6 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Fzo_mitofusin PF04799.11 001288218.1_48625001_1 - 0.64 9.4 4.6 1.2 8.5 4.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region DAHP_synth_2 PF01474.14 001288470.1_48624001_2 - 5.4e-196 651.2 0.0 6.3e-196 651.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Actin PF00022.17 001288158.1_48623001_2 - 3.5e-146 486.9 0.0 1e-145 485.3 0.0 1.6 1 1 0 1 1 1 1 Actin GDC-P PF02347.14 001318671.1_48627001_3 - 2.8e-198 659.0 0.1 8.2e-184 611.3 0.1 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Aminotran_5 PF00266.17 001318671.1_48627001_3 - 3.7e-06 26.0 0.7 0.00022 20.2 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.19 001318671.1_48627001_3 - 0.00095 18.4 0.1 0.0024 17.1 0.1 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.18 001318671.1_48627001_3 - 0.026 12.9 3.1 0.029 12.8 0.0 2.4 3 0 0 3 3 3 0 Cys/Met metabolism PLP-dependent enzyme Transketolase_N PF00456.19 001288273.1_48625001_1 - 1.2e-152 507.5 0.0 1.7e-152 507.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.22 001288273.1_48625001_1 - 7.1e-43 146.2 0.0 1.2e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 001288273.1_48625001_1 - 1.8e-14 53.5 0.0 1.4e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain XFP_C PF09363.8 001288273.1_48625001_1 - 0.073 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 XFP C-terminal domain DUF1563 PF07599.9 001288273.1_48625001_3 - 0.041 13.9 0.4 0.071 13.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) Whirly PF08536.9 001288464.1_48622001_1 - 2.8e-59 198.7 0.0 3.5e-59 198.4 0.0 1.1 1 0 0 1 1 1 1 Whirly transcription factor PPDK_N PF01326.17 001288123.1_48629001_1 - 6.8e-22 78.0 1.6 4.7e-18 65.4 0.0 4.5 3 1 0 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain VasL PF12486.6 001288123.1_48629001_1 - 0.008 15.9 11.3 0.0092 15.7 0.5 3.1 2 1 1 3 3 3 2 Type VI secretion system, EvfB, or VasL DUF4164 PF13747.4 001288123.1_48629001_1 - 3.5 7.9 7.2 0.68 10.1 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Pyr_redox_2 PF07992.12 001287925.1_48625001_3 - 1.6e-56 191.6 0.1 2.2e-56 191.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001287925.1_48625001_3 - 5.3e-12 46.0 0.0 2.6e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.22 001287925.1_48625001_3 - 6.7e-07 29.1 0.5 0.00036 20.1 0.0 3.1 1 1 2 3 3 3 2 FAD dependent oxidoreductase EF-hand_1 PF00036.30 001287925.1_48625001_3 - 6.9e-05 22.0 0.4 0.00015 21.0 0.4 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.4 001287925.1_48625001_3 - 0.00028 20.5 0.1 0.00085 18.9 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.4 001287925.1_48625001_3 - 0.00047 19.4 0.1 0.00092 18.5 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.4 001287925.1_48625001_3 - 0.0034 17.7 0.5 0.0081 16.5 0.5 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.4 001287925.1_48625001_3 - 0.0035 16.9 0.6 0.0082 15.8 0.6 1.6 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.4 001287925.1_48625001_3 - 0.0097 15.0 0.2 1.1 8.3 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Tctex-1 PF03645.11 001287925.1_48625001_3 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Tctex-1 family DAHP_synth_2 PF01474.14 001288432.1_48624001_3 - 6.5e-195 647.6 0.0 7.6e-195 647.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family TLC PF03219.12 001287865.1_48625001_3 - 9.1e-199 661.1 16.3 1.2e-198 660.7 16.3 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter PLAC8 PF04749.15 001195207.1_53725001_1 - 1e-15 58.3 18.1 1e-15 58.3 18.1 2.0 2 0 0 2 2 2 1 PLAC8 family Lipoxygenase PF00305.17 001288240.1_48626001_1 - 0 1061.4 0.0 0 1061.2 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001288240.1_48626001_1 - 2.1e-20 73.3 0.0 4.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Hexokinase_2 PF03727.14 001287912.1_48624001_1 - 5.2e-81 271.5 0.0 8.4e-81 270.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.19 001287912.1_48624001_1 - 9.4e-66 221.4 0.0 1.4e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PAP_fibrillin PF04755.10 001288132.1_48623001_3 - 3.4e-81 271.8 0.2 5e-81 271.3 0.2 1.3 1 0 0 1 1 1 1 PAP_fibrillin CBM53 PF16760.3 001287873.1_48628001_3 - 1.1e-55 186.0 6.5 7.2e-18 64.8 0.3 3.5 3 0 0 3 3 3 3 Starch/carbohydrate-binding module (family 53) Glyco_transf_5 PF08323.9 001287873.1_48628001_3 - 9.5e-49 166.2 0.2 1.5e-46 158.9 0.2 2.5 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.4 001287873.1_48628001_3 - 4.7e-11 42.8 0.0 1.2e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.18 001287873.1_48628001_3 - 8e-07 28.7 0.0 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.4 001287873.1_48628001_3 - 2.8e-06 27.7 0.0 2e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.4 001287873.1_48628001_3 - 2.9e-05 24.4 0.0 6.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 CBM_25 PF03423.11 001287873.1_48628001_3 - 0.0016 18.5 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 Carbohydrate binding domain (family 25) DUF4056 PF13265.4 001287873.1_48628001_3 - 0.2 10.8 1.0 2.4 7.3 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4056) S-AdoMet_synt_C PF02773.14 001318549.1_48624001_3 - 5.2e-61 204.5 0.3 1.2e-60 203.4 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.14 001318549.1_48624001_3 - 4.4e-47 159.1 0.0 9.2e-47 158.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.18 001318549.1_48624001_3 - 3.1e-42 143.1 0.4 7.7e-42 141.9 0.4 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Iso_dh PF00180.18 001316091.1_06923001_2 - 1.3e-139 465.1 0.0 1.6e-139 464.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Patatin PF01734.20 001288416.1_48623001_1 - 1.5e-16 61.1 0.0 2.9e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase S-AdoMet_synt_C PF02773.14 001288680.1_48623001_3 - 4.4e-62 208.0 0.2 1.5e-61 206.3 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.14 001288680.1_48623001_3 - 1e-45 154.6 0.0 1.9e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.18 001288680.1_48623001_3 - 8e-43 145.0 0.4 1.9e-42 143.8 0.4 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Fer4 PF00037.25 001288285.1_48622001_2 - 5.1e-14 51.3 16.9 2.2e-08 33.4 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.5 001288285.1_48622001_2 - 4.1e-13 49.6 10.5 6.9e-13 48.8 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.4 001288285.1_48622001_2 - 1.8e-10 41.5 6.3 5.9e-05 23.8 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.4 001288285.1_48622001_2 - 6.5e-09 35.7 31.5 7.2e-06 25.9 12.3 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.4 001288285.1_48622001_2 - 1.7e-08 34.3 20.9 1.6e-06 28.0 12.0 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.4 001288285.1_48622001_2 - 2e-08 34.1 10.5 3.2e-08 33.5 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.5 001288285.1_48622001_2 - 5.9e-07 29.2 17.8 0.00051 19.9 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.5 001288285.1_48622001_2 - 8.2e-07 28.6 12.1 0.0036 17.2 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.4 001288285.1_48622001_2 - 9.3e-07 29.1 18.2 0.00043 20.5 11.6 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.5 001288285.1_48622001_2 - 1.4e-05 25.1 11.4 0.00045 20.4 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.4 001288285.1_48622001_2 - 0.00056 20.3 12.3 0.047 14.1 13.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.8 001288285.1_48622001_2 - 0.025 14.7 6.3 0.43 10.7 0.4 2.4 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.4 001288285.1_48622001_2 - 0.025 15.0 14.9 0.84 10.1 2.8 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.4 001288285.1_48622001_2 - 0.039 14.0 8.7 2 8.5 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.11 001288285.1_48622001_2 - 0.09 12.8 5.1 0.33 11.0 0.4 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.5 001288285.1_48622001_2 - 0.32 11.9 16.4 0.43 11.5 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.2 001288285.1_48622001_2 - 2.6 8.8 14.0 4.1 8.2 2.0 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Lar_restr_allev PF14354.4 001288285.1_48622001_2 - 6 7.2 12.3 10 6.4 1.0 3.2 2 1 1 3 3 3 0 Restriction alleviation protein Lar Hexokinase_2 PF03727.14 001318690.1_48624001_1 - 1.8e-76 256.6 0.0 3.4e-76 255.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.19 001318690.1_48624001_1 - 2.1e-46 158.3 0.0 3.5e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.19 001318690.1_48624001_3 - 0.0095 15.8 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase E1_dh PF00676.18 001288457.1_48624001_1 - 2.2e-115 384.6 0.0 2.6e-115 384.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.4 001288457.1_48624001_1 - 4e-06 26.1 0.0 9.1e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.19 001288457.1_48624001_1 - 5.9e-06 26.0 1.2 1.1e-05 25.1 0.3 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.19 001288457.1_48624001_1 - 0.093 11.5 0.0 0.19 10.5 0.0 1.4 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain NAD_binding_6 PF08030.10 001318578.1_48626001_1 - 9.4e-49 165.4 0.0 1.9e-48 164.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NADPH_Ox PF08414.8 001318578.1_48626001_1 - 5.8e-35 119.5 2.6 9.9e-35 118.7 0.7 2.4 3 0 0 3 3 3 1 Respiratory burst NADPH oxidase FAD_binding_8 PF08022.10 001318578.1_48626001_1 - 1.1e-31 108.9 0.0 2.5e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.17 001318578.1_48626001_1 - 6.6e-21 74.6 0.5 1.5e-20 73.4 0.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.4 001318578.1_48626001_1 - 7.3e-08 32.7 5.1 2.6e-05 24.5 0.6 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001318578.1_48626001_1 - 2.2e-07 29.8 1.6 0.0017 17.6 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.4 001318578.1_48626001_1 - 9.3e-06 25.1 0.3 0.00032 20.3 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain FAD_binding_6 PF00970.22 001318578.1_48626001_1 - 0.006 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain EF-hand_5 PF13202.4 001318578.1_48626001_1 - 0.011 15.1 1.9 0.029 13.8 0.3 2.5 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.4 001318578.1_48626001_1 - 0.29 10.8 1.1 23 4.7 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair 2OG-FeII_Oxy PF03171.18 001287997.1_48623001_1 - 1.2e-26 93.0 0.1 2.3e-26 92.1 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001287997.1_48623001_1 - 5e-25 88.4 0.1 7.9e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Chalcone PF02431.13 001150530.2_53723001_1 - 1.1e-88 295.8 0.0 1.4e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Mito_carr PF00153.25 001288356.1_48623001_2 - 8.7e-68 224.2 3.0 1.5e-24 85.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_88 PF07470.11 001288356.1_48623001_2 - 0.025 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Porin_3 PF01459.20 001291615.1_53723001_1 - 5e-67 226.1 4.4 5.8e-67 225.9 4.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4421 PF14391.4 001291615.1_53723001_1 - 0.075 12.3 0.1 0.075 12.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4421) Lactococcin_972 PF09683.8 001291615.1_53723001_1 - 0.3 11.5 1.8 0.68 10.4 1.8 1.6 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) NAD_binding_6 PF08030.10 001288524.1_48626001_1 - 1.5e-50 171.3 0.0 2.4e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NADPH_Ox PF08414.8 001288524.1_48626001_1 - 1.4e-39 134.3 0.2 2.2e-38 130.5 0.1 2.5 1 1 1 2 2 2 1 Respiratory burst NADPH oxidase FAD_binding_8 PF08022.10 001288524.1_48626001_1 - 2.7e-35 120.6 0.0 5.3e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.17 001288524.1_48626001_1 - 5.3e-24 84.6 3.9 5.3e-24 84.6 3.9 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.4 001288524.1_48626001_1 - 9.9e-08 32.2 2.2 9.4e-05 22.7 0.1 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001288524.1_48626001_1 - 2.7e-06 26.4 0.5 0.00044 19.5 0.3 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.4 001288524.1_48626001_1 - 6.9e-05 22.3 0.1 0.00024 20.6 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.4 001288524.1_48626001_1 - 0.0019 17.5 0.4 0.0056 16.0 0.4 1.9 1 0 0 1 1 1 1 EF hand NTP_transferase PF00483.21 001288195.1_48624001_1 - 1.1e-66 224.9 0.0 1.4e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001288195.1_48624001_1 - 1.2e-05 25.6 0.0 2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001288195.1_48624001_1 - 0.0036 16.8 11.6 0.035 13.7 2.3 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) zf-RVT PF13966.4 001165864.2_53725001_1 - 0.0055 17.4 0.1 0.013 16.2 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-RVT PF13966.4 001165864.2_53725001_2 - 0.00062 20.4 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HIT PF01230.21 001254774.2_53722001_3 - 7e-30 103.5 0.0 9.7e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.6 001254774.2_53722001_3 - 4.9e-20 72.0 0.0 7.1e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Peptidase_M41 PF01434.16 001151857.2_53726001_2 - 3.2e-76 255.5 0.4 4.5e-76 255.1 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.27 001151857.2_53726001_2 - 7.7e-42 142.7 0.0 2.8e-41 140.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.13 001151857.2_53726001_2 - 2.5e-10 40.5 0.0 9.4e-10 38.7 0.0 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.12 001151857.2_53726001_2 - 0.0012 18.7 0.0 0.0066 16.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.4 001151857.2_53726001_2 - 0.0026 17.9 0.1 0.46 10.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.11 001151857.2_53726001_2 - 0.0031 16.4 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.10 001151857.2_53726001_2 - 0.004 16.3 0.0 0.029 13.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.12 001151857.2_53726001_2 - 0.013 15.5 0.0 0.045 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.4 001151857.2_53726001_2 - 0.021 14.9 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.4 001151857.2_53726001_2 - 0.021 15.1 0.2 0.13 12.5 0.2 2.2 1 1 1 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.19 001151857.2_53726001_2 - 0.076 12.2 0.3 0.2 10.9 0.3 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.15 001151857.2_53726001_2 - 0.15 11.7 0.2 0.31 10.6 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DHDPS PF00701.20 001111955.2_53724001_1 - 1.4e-91 306.1 0.0 1.7e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ATP-synt_B PF00430.16 001153915.1_53722001_1 - 4e-28 98.0 7.2 6.3e-28 97.4 7.2 1.3 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) SUIM_assoc PF16619.3 001153915.1_53722001_1 - 0.44 10.6 5.3 0.19 11.7 0.5 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 4F5 PF04419.12 001351629.2_53722001_1 - 9.4e-09 35.9 4.3 9.4e-09 35.9 4.3 2.3 2 0 0 2 2 2 2 4F5 protein family DUF632 PF04782.10 001348782.1_53726001_1 - 1.7e-89 300.1 0.1 2.5e-89 299.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF632) DUF630 PF04783.10 001348782.1_53726001_1 - 1.8e-24 85.5 1.6 1.8e-24 85.5 1.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF630) zf-C2H2 PF00096.24 001143084.1_53724001_2 - 3.6e-18 64.8 26.6 0.00026 21.1 0.7 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001143084.1_53724001_2 - 1.3e-14 53.5 24.8 0.021 15.5 0.5 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001143084.1_53724001_2 - 1.4e-05 25.1 37.5 0.00025 21.2 1.9 6.6 7 0 0 7 7 7 4 Zinc-finger double domain FOXP-CC PF16159.3 001143084.1_53724001_2 - 0.00084 19.8 10.8 13 6.3 0.1 5.5 2 1 3 5 5 5 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.3 001143084.1_53724001_2 - 0.0046 17.1 7.5 0.13 12.5 0.6 3.2 2 1 0 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.6 001143084.1_53724001_2 - 0.067 13.4 11.1 21 5.4 0.0 5.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding IBR PF01485.19 001143084.1_53724001_2 - 0.14 12.3 8.6 1.8 8.7 0.2 3.9 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-DNA_Pol PF08996.8 001143084.1_53724001_2 - 0.17 11.5 1.7 3.7 7.2 0.4 2.4 1 1 0 2 2 2 0 DNA Polymerase alpha zinc finger Ogr_Delta PF04606.10 001143084.1_53724001_2 - 0.76 9.7 6.5 13 5.7 0.1 3.7 2 2 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_aberr PF17017.3 001143084.1_53724001_2 - 1.8 8.6 15.8 18 5.3 1.2 4.3 2 1 2 5 5 5 0 Aberrant zinc-finger Jas PF16135.3 001174644.1_53727001_2 - 8.6e-27 93.0 12.0 1.7e-19 69.6 0.0 4.3 4 1 0 4 4 4 2 TPL-binding domain in jasmonate signalling PHD PF00628.27 001174644.1_53727001_2 - 1.7e-08 34.1 36.8 1.3e-05 24.8 5.0 4.4 4 0 0 4 4 4 2 PHD-finger PHD_2 PF13831.4 001174644.1_53727001_2 - 0.0034 16.7 1.6 0.0034 16.7 1.6 4.4 4 1 0 4 4 4 1 PHD-finger Zf_RING PF16744.3 001174644.1_53727001_2 - 0.0061 16.5 0.7 0.0061 16.5 0.7 4.1 4 1 1 5 5 5 2 KIAA1045 RING finger Glyco_hydro_52 PF03512.11 001174644.1_53727001_2 - 0.049 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 zf-HC5HC2H PF13771.4 001174644.1_53727001_2 - 0.11 12.6 17.5 0.31 11.2 1.1 3.4 3 0 0 3 3 3 0 PHD-like zinc-binding domain zf-4CXXC_R1 PF10497.7 001174644.1_53727001_2 - 3.2 7.9 19.1 0.73 10.0 3.8 3.7 4 0 0 4 4 4 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF3143 PF11341.6 001150810.2_53722001_3 - 3.2e-22 78.5 0.0 5.1e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3143) Nucleotid_trans PF03407.14 001143226.1_53723001_1 - 4.3e-62 209.7 0.0 5.9e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase adh_short_C2 PF13561.4 001291620.1_53723001_3 - 4.2e-57 193.3 3.2 5.4e-57 192.9 3.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001291620.1_53723001_3 - 9.5e-42 142.5 1.2 1.2e-41 142.2 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001291620.1_53723001_3 - 2.6e-08 33.8 0.8 2.6e-08 33.8 0.8 1.6 2 0 0 2 2 2 1 KR domain peroxidase PF00141.21 001143307.1_53724001_1 - 4.3e-65 219.5 0.0 5.7e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Trypan_PARP PF05887.9 001143307.1_53724001_1 - 2.1 8.2 6.3 0.28 11.1 1.9 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cullin_binding PF03556.13 001150944.1_53723001_1 - 1.7e-27 96.1 0.1 2.8e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 Cullin binding HLH PF00010.24 001174894.1_53726001_2 - 0.00039 20.2 0.3 0.00071 19.4 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Dev_Cell_Death PF10539.7 001150970.1_53723001_1 - 7.7e-45 151.7 0.1 1.3e-44 151.0 0.1 1.4 1 0 0 1 1 1 1 Development and cell death domain GST_N_3 PF13417.4 001153314.1_53723001_3 - 1.2e-16 60.7 0.0 2.2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001153314.1_53723001_3 - 7.4e-15 54.9 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001153314.1_53723001_3 - 3.1e-12 46.1 0.1 8.7e-12 44.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001153314.1_53723001_3 - 7.3e-11 42.1 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001153314.1_53723001_3 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.3 001153314.1_53723001_3 - 0.0001 22.7 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001153314.1_53723001_3 - 0.0077 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain XPG_I PF00867.16 001155891.1_53725001_2 - 2.2e-19 69.4 0.0 5.2e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.15 001155891.1_53725001_2 - 1.1e-12 48.2 0.0 2.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Epimerase PF01370.19 001155905.2_53723001_2 - 5.7e-25 88.0 0.0 1.5e-24 86.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001155905.2_53723001_2 - 4.6e-21 74.9 0.0 5.9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001155905.2_53723001_2 - 1.6e-13 50.8 0.0 2.8e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.3 001155905.2_53723001_2 - 1.3e-11 44.4 0.0 2.4e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.10 001155905.2_53723001_2 - 2.9e-11 42.9 0.0 5.7e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.11 001155905.2_53723001_2 - 9.1e-07 28.5 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.13 001155905.2_53723001_2 - 1.9e-06 27.1 0.0 4.4e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.23 001155905.2_53723001_2 - 4.8e-05 22.8 0.1 0.012 14.9 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.8 001155905.2_53723001_2 - 5.8e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.15 001155905.2_53723001_2 - 0.0019 17.3 0.0 0.0064 15.5 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Myb_DNA-binding PF00249.29 001174989.1_53723001_1 - 1.4e-31 108.2 1.0 1.2e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001174989.1_53723001_1 - 3.6e-17 62.2 0.4 2.4e-10 40.4 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain zf-RING_2 PF13639.4 001151076.1_53723001_3 - 1.4e-11 44.3 0.9 3.2e-11 43.2 0.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.4 001151076.1_53723001_3 - 5.8e-09 35.5 1.4 1.2e-08 34.5 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001151076.1_53723001_3 - 6.3e-08 32.2 0.9 1.8e-07 30.8 0.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001151076.1_53723001_3 - 7.3e-08 32.4 4.8 2e-07 31.1 4.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001151076.1_53723001_3 - 2.5e-07 30.2 1.2 4.9e-07 29.2 1.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.4 001151076.1_53723001_3 - 3.7e-05 23.5 1.7 9e-05 22.3 1.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.5 001151076.1_53723001_3 - 0.00017 21.4 2.2 0.00039 20.3 2.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.4 001151076.1_53723001_3 - 0.00069 19.3 0.5 0.0018 18.0 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001151076.1_53723001_3 - 0.0012 18.6 0.8 0.0012 18.6 0.8 1.8 2 0 0 2 2 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.3 001151076.1_53723001_3 - 0.0023 17.4 0.8 0.0046 16.4 0.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.6 001151076.1_53723001_3 - 0.016 15.3 0.7 0.039 14.0 0.7 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.5 001151076.1_53723001_3 - 0.066 13.2 2.3 0.19 11.7 2.3 1.8 1 0 0 1 1 1 0 RING-variant domain RRM_1 PF00076.20 001143479.1_53723001_3 - 6.1e-20 70.7 0.0 6.7e-09 35.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDA1 PF05285.10 001143479.1_53723001_3 - 9.5 5.4 9.3 13 5.0 9.3 1.1 1 0 0 1 1 1 0 SDA1 CHD5 PF04420.12 001143493.1_53723001_3 - 0.01 15.6 1.6 0.45 10.2 0.1 2.2 2 0 0 2 2 2 0 CHD5-like protein WCOR413 PF05562.9 001351707.1_53723001_1 - 3.4e-55 186.7 1.9 4.8e-55 186.2 1.9 1.2 1 0 0 1 1 1 1 Cold acclimation protein WCOR413 Pkinase_Tyr PF07714.15 001358414.1_53729001_2 - 3.7e-62 209.8 0.0 5.1e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001358414.1_53729001_2 - 1.7e-51 175.0 0.0 2.6e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PB1 PF00564.22 001358414.1_53729001_2 - 4.1e-21 74.5 0.4 9.2e-21 73.4 0.0 1.8 2 0 0 2 2 2 1 PB1 domain Kdo PF06293.12 001358414.1_53729001_2 - 0.043 13.0 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WRC PF08879.8 001175218.1_53722001_1 - 1.3e-12 47.1 4.6 1.3e-12 47.1 4.6 1.8 2 0 0 2 2 2 1 WRC CAP_N PF01213.17 001175218.1_53722001_1 - 0.039 13.3 5.2 0.066 12.5 5.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cpn60_TCP1 PF00118.22 001146752.2_53725001_3 - 1.4e-83 281.0 20.7 3.6e-83 279.7 20.7 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec1 PF00995.21 001175299.1_53722001_1 - 7e-07 28.7 0.0 8.6e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Tubulin PF00091.23 001111990.1_53724001_1 - 1.3e-70 237.5 0.1 2.2e-70 236.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001111990.1_53724001_1 - 6.4e-46 155.5 0.3 1.2e-45 154.7 0.3 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001111990.1_53724001_1 - 0.00076 19.6 0.0 0.0041 17.3 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.4 001111990.1_53724001_1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Tubulin like DSPn PF14671.4 001111990.1_53724001_1 - 0.041 14.2 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half WD40 PF00400.30 001354132.1_53724001_2 - 3.3e-10 40.2 3.0 0.00013 22.5 0.3 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.3 001354132.1_53724001_2 - 0.0024 16.8 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein bZIP_1 PF00170.19 001156479.1_53724001_1 - 9.7e-13 47.9 13.3 1.6e-12 47.2 13.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001156479.1_53724001_1 - 5e-10 39.2 14.6 8.6e-10 38.4 14.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001156479.1_53724001_1 - 0.00035 20.9 8.5 0.00035 20.9 8.5 2.1 2 1 0 2 2 2 1 bZIP Maf transcription factor DivIC PF04977.13 001156479.1_53724001_1 - 0.22 11.2 5.4 0.44 10.2 5.4 1.5 1 0 0 1 1 1 0 Septum formation initiator OmpH PF03938.12 001156479.1_53724001_1 - 2.6 7.9 8.6 18 5.1 7.3 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Profilin PF00235.17 001151534.1_53722001_3 - 2.2e-05 24.6 0.0 2.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Profilin CAP_N PF01213.17 001151573.1_53722001_2 - 0.75 9.1 2.1 1.1 8.5 2.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_100 PF12899.5 001353446.1_53725001_3 - 1.2e-215 716.1 0.0 1.4e-215 715.9 0.0 1.0 1 0 0 1 1 1 1 Alkaline and neutral invertase GDE_C PF06202.12 001353446.1_53725001_3 - 8.1e-06 24.9 0.0 0.0015 17.4 0.0 2.9 2 1 0 2 2 2 2 Amylo-alpha-1,6-glucosidase Pkinase_Tyr PF07714.15 001147009.1_53724001_1 - 7.1e-38 130.2 0.0 9.7e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001147009.1_53724001_1 - 3.7e-32 111.6 0.0 4.8e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.21 001147009.1_53724001_1 - 0.01 15.6 0.3 0.26 11.0 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family PUF PF00806.17 001175716.1_53726001_2 - 6.6e-41 135.6 16.6 1.9e-06 27.1 0.1 8.7 8 1 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.9 001175716.1_53726001_2 - 0.19 12.0 0.4 6.1 7.1 0.0 3.3 2 2 3 5 5 5 0 CPL (NUC119) domain Ras PF00071.20 001175787.1_53722001_2 - 1e-56 190.9 0.1 1.2e-56 190.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001175787.1_53722001_2 - 1.7e-32 112.1 0.0 2.3e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001175787.1_53722001_2 - 1.1e-12 47.7 0.0 1.4e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001175787.1_53722001_2 - 3.5e-07 30.2 0.0 4.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001175787.1_53722001_2 - 1e-06 28.2 0.0 1.3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001175787.1_53722001_2 - 8.9e-06 25.2 0.0 0.00016 21.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001175787.1_53722001_2 - 0.0016 18.2 0.0 0.0048 16.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.4 001175787.1_53722001_2 - 0.0037 17.5 0.0 0.0054 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 001175787.1_53722001_2 - 0.017 15.2 0.0 0.036 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.8 001175787.1_53722001_2 - 0.02 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.15 001175787.1_53722001_2 - 0.025 14.2 0.1 0.78 9.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.16 001175787.1_53722001_2 - 0.03 13.4 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_24 PF13479.4 001175787.1_53722001_2 - 0.036 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.16 001175787.1_53722001_2 - 0.066 13.0 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.7 001175787.1_53722001_2 - 0.08 12.5 0.1 0.25 10.9 0.1 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.17 001175787.1_53722001_2 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.13 001175787.1_53722001_2 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 NTPase NACHT PF05729.10 001175787.1_53722001_2 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.9 001175787.1_53722001_2 - 0.18 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein MatE PF01554.16 001349988.1_53729001_3 - 6.5e-63 211.1 23.7 4.2e-35 120.6 12.1 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.4 001349988.1_53729001_3 - 9.7e-08 32.1 4.6 9.7e-08 32.1 4.6 3.8 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain CCDC144C PF14915.4 001147115.1_53723001_2 - 0.00028 20.0 6.6 0.00046 19.3 6.6 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region BRE1 PF08647.9 001147115.1_53723001_2 - 0.00052 19.9 5.6 0.00098 19.0 5.6 1.4 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase IncA PF04156.12 001147115.1_53723001_2 - 0.00063 19.4 2.9 0.0013 18.4 2.9 1.5 1 0 0 1 1 1 1 IncA protein DUF2968 PF11180.6 001147115.1_53723001_2 - 0.00094 18.8 5.9 0.002 17.8 5.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.7 001147115.1_53723001_2 - 0.0013 18.6 6.1 0.0024 17.8 6.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.9 001147115.1_53723001_2 - 0.0024 18.0 8.8 0.0024 18.0 8.8 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) FlaC_arch PF05377.9 001147115.1_53723001_2 - 0.0071 16.6 4.4 0.48 10.7 0.1 2.7 3 0 0 3 3 2 1 Flagella accessory protein C (FlaC) GAS PF13851.4 001147115.1_53723001_2 - 0.013 14.7 4.8 0.025 13.8 4.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding KLRAQ PF10205.7 001147115.1_53723001_2 - 0.02 15.0 3.3 0.046 13.8 3.3 1.6 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Fez1 PF06818.13 001147115.1_53723001_2 - 0.03 14.6 6.8 0.059 13.7 6.8 1.4 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.9 001147115.1_53723001_2 - 0.058 12.1 5.0 0.089 11.5 5.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.6 001147115.1_53723001_2 - 0.11 11.7 4.6 0.2 10.8 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.6 001147115.1_53723001_2 - 0.14 12.1 6.9 0.3 11.0 6.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CCDC158 PF15921.3 001147115.1_53723001_2 - 0.17 9.6 5.3 0.24 9.0 5.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 Mnd1 PF03962.13 001147115.1_53723001_2 - 0.21 11.3 4.5 0.42 10.3 4.5 1.4 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.10 001147115.1_53723001_2 - 0.33 10.2 6.0 0.72 9.1 6.0 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 HMMR_C PF15908.3 001147115.1_53723001_2 - 0.35 11.0 4.2 6.9 6.8 0.1 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal TMF_DNA_bd PF12329.6 001147115.1_53723001_2 - 0.45 10.4 8.1 3.4 7.6 2.3 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.13 001147115.1_53723001_2 - 0.46 10.2 9.5 1.9 8.2 1.5 2.5 1 1 1 2 2 2 0 Septum formation initiator ERM PF00769.17 001147115.1_53723001_2 - 1.1 8.9 14.8 2.2 7.9 14.8 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ZapB PF06005.10 001147115.1_53723001_2 - 1.5 9.1 12.7 1.3 9.3 1.3 3.2 2 1 1 3 3 3 0 Cell division protein ZapB DUF4472 PF14739.4 001147115.1_53723001_2 - 1.7 9.3 7.0 2.2 8.9 1.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) TBPIP PF07106.11 001147115.1_53723001_2 - 2.4 7.8 5.6 7.5 6.2 1.8 2.3 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.4 001147115.1_53723001_2 - 2.7 8.3 7.2 2.5 8.4 5.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF5082 PF16888.3 001147115.1_53723001_2 - 2.8 8.2 5.5 2.2 8.5 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) KfrA_N PF11740.6 001147115.1_53723001_2 - 4.5 7.9 16.2 0.14 12.7 4.5 2.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term SOGA PF11365.6 001147115.1_53723001_2 - 6.9 7.7 10.3 3.9 8.5 2.7 2.6 1 1 1 2 2 2 0 Protein SOGA Tetraspannin PF00335.18 001175822.1_53723001_1 - 8.7e-28 97.4 9.2 1.1e-27 97.0 9.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3268 PF11672.6 001175822.1_53723001_1 - 0.043 14.0 1.0 0.071 13.3 1.0 1.3 1 0 0 1 1 1 0 zinc-finger-containing domain EI24 PF07264.9 001175822.1_53723001_1 - 0.28 11.3 9.2 0.52 10.4 7.2 2.1 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF4233 PF14017.4 001175822.1_53723001_1 - 1.7 8.9 16.6 0.74 10.0 9.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) DUF2593 PF10767.7 001175822.1_53723001_1 - 5.5 7.0 7.8 2.6 8.1 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) Kinesin PF00225.21 001291655.1_53725001_1 - 4.4e-107 357.7 0.0 6.4e-107 357.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.3 001291655.1_53725001_1 - 2.7e-21 75.9 0.0 9.6e-21 74.2 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding CENP-F_leu_zip PF10473.7 001291655.1_53725001_1 - 0.28 11.1 38.0 0.035 14.0 13.9 3.4 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.9 001291655.1_53725001_1 - 1.5 7.2 25.6 0.0063 15.0 12.0 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like MSG PF02349.13 001291655.1_53725001_1 - 2.3 8.4 9.9 9.3 6.4 9.9 2.2 1 1 0 1 1 1 0 Major surface glycoprotein E6 PF00518.15 001291655.1_53725001_1 - 3.2 8.1 8.1 0.76 10.1 0.8 3.1 2 1 1 3 3 3 0 Early Protein (E6) GAS PF13851.4 001291655.1_53725001_1 - 5.5 6.2 27.4 1.4 8.1 11.9 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3444 PF11926.6 001350032.1_53727001_2 - 9.5e-76 254.0 0.1 1.5e-75 253.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3444) DnaJ PF00226.29 001350032.1_53727001_2 - 7.5e-23 80.3 0.1 1.6e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain SprT-like PF10263.7 001350032.1_53727001_2 - 0.068 12.9 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 SprT-like family Glyoxalase PF00903.23 001156847.2_53722001_3 - 1.3e-11 44.7 0.0 2.1e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.4 001156847.2_53722001_3 - 5e-06 26.6 0.0 8.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.4 001156847.2_53722001_3 - 0.016 15.2 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Staygreen PF12638.5 001112300.2_53724001_2 - 5.9e-54 181.8 0.0 1e-53 181.0 0.0 1.4 1 1 0 1 1 1 1 Staygreen protein Staygreen PF12638.5 001112301.2_53724001_2 - 1.6e-56 190.1 0.0 2.2e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Staygreen protein Cyclin_N PF00134.21 001175879.1_53723001_1 - 5.6e-23 81.0 0.3 1.4e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001175879.1_53723001_1 - 2.2e-05 24.4 1.0 8.8e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cu_bind_like PF02298.15 001156908.1_53722001_2 - 7.3e-19 67.4 0.0 1.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Plastocyanin-like domain Rad21_Rec8_N PF04825.11 001112359.2_53725001_1 - 6.4e-35 119.5 0.0 1.3e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.14 001112359.2_53725001_1 - 1.6e-12 46.4 0.1 6.7e-12 44.4 0.0 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein Transket_pyr PF02779.22 001176065.1_53726001_1 - 3.5e-67 225.4 0.1 6.7e-67 224.5 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.18 001176065.1_53726001_1 - 1.4e-63 214.5 0.0 2e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.3 001176065.1_53726001_1 - 2.6e-52 176.4 0.0 4.6e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Mrx7 PF10906.6 001176065.1_53726001_1 - 0.074 13.2 0.4 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 MIOREX complex component 7 WD40 PF00400.30 001147394.1_53724001_1 - 1e-20 73.5 1.3 4.1e-07 30.5 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001147394.1_53724001_1 - 3.3e-06 27.2 0.0 1.3 9.2 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF295 PF03478.16 001147394.1_53724001_1 - 0.063 13.0 1.4 19 5.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF295) SDA1 PF05285.10 001147394.1_53724001_1 - 7.1 5.8 9.0 11 5.2 9.0 1.2 1 0 0 1 1 1 0 SDA1 NmrA PF05368.11 001147421.1_53723001_2 - 0.00065 19.2 0.0 0.00085 18.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.4 001147421.1_53723001_2 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding MMM1 PF10296.7 001350277.1_53726001_2 - 6.4e-05 22.0 0.0 0.0029 16.6 0.0 2.3 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 PH PF00169.27 001350277.1_53726001_2 - 0.00091 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 PH domain CAMSAP_CC1 PF17095.3 001350277.1_53726001_2 - 1.1 9.1 5.1 2.6 7.8 5.1 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Peptidase_S8 PF00082.20 001176132.1_53726001_2 - 2.4e-50 171.4 1.9 3.4e-50 170.9 1.9 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.14 001176132.1_53726001_2 - 9.3e-17 61.3 0.0 1.9e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 PA PF02225.20 001176132.1_53726001_2 - 1.9e-07 31.0 0.0 4.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PA domain PK PF00224.19 001147449.1_53724001_1 - 3.2e-117 391.2 4.8 4.1e-117 390.8 4.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.14 001147449.1_53724001_1 - 3.4e-18 65.8 0.2 1.4e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.12 001147449.1_53724001_1 - 0.015 14.3 0.2 0.054 12.5 0.1 1.9 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.23 001147449.1_53724001_1 - 0.021 13.7 4.7 0.013 14.4 1.7 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.16 001147449.1_53724001_1 - 0.034 13.5 0.2 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Myosin_head PF00063.19 001349815.1_53729001_1 - 7.5e-258 857.1 0.6 1.5e-257 856.1 0.6 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.17 001349815.1_53729001_1 - 2.4e-25 88.7 11.0 9.1e-25 86.8 0.6 3.7 3 0 0 3 3 3 1 DIL domain IQ PF00612.25 001349815.1_53729001_1 - 1.9e-22 76.7 27.7 0.00049 19.5 2.1 6.9 6 0 0 6 6 6 6 IQ calmodulin-binding motif Myosin_N PF02736.17 001349815.1_53729001_1 - 2.2e-12 46.5 5.9 4.1e-12 45.6 5.9 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.4 001349815.1_53729001_1 - 0.0067 16.7 4.1 0.026 14.8 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Hpr_kinase_C PF07475.10 001349815.1_53729001_1 - 0.023 14.1 0.4 1.1 8.6 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain TsaE PF02367.15 001349815.1_53729001_1 - 0.099 12.5 0.0 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.4 001349815.1_53729001_1 - 0.13 12.4 0.1 1.3 9.1 0.1 2.8 1 0 0 1 1 1 0 AAA domain Agenet PF05641.10 001349815.1_53729001_1 - 0.16 12.4 0.3 0.46 10.9 0.3 1.8 1 0 0 1 1 1 0 Agenet domain DUF87 PF01935.15 001349815.1_53729001_1 - 1.2 9.0 9.2 3.6 7.4 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Flp1_like PF16982.3 001349815.1_53729001_1 - 1.4 8.3 4.4 1.1 8.6 0.1 2.9 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain DUF2894 PF11445.6 001349815.1_53729001_1 - 2.6 8.4 11.5 0.21 11.9 5.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2894) Epimerase PF01370.19 001136805.1_53723001_3 - 6.3e-15 55.2 0.0 4.9e-14 52.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.4 001136805.1_53723001_3 - 1.5e-08 34.6 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.17 001136805.1_53723001_3 - 2.8e-08 32.9 0.0 5.7e-08 31.9 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.3 001136805.1_53723001_3 - 3.6e-07 29.7 0.0 3.9e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.11 001136805.1_53723001_3 - 4.9e-05 22.9 0.0 7.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.10 001136805.1_53723001_3 - 0.00014 21.0 1.9 0.001 18.2 1.9 2.0 1 1 0 1 1 1 1 Male sterility protein KR PF08659.8 001136805.1_53723001_3 - 0.0013 18.6 0.1 0.069 12.9 0.0 2.8 3 0 0 3 3 3 1 KR domain adh_short PF00106.23 001136805.1_53723001_3 - 0.044 13.1 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.15 001136805.1_53723001_3 - 0.097 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Hexokinase_2 PF03727.14 001130127.1_53724001_1 - 3.2e-80 268.9 0.0 1e-79 267.3 0.0 1.8 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.19 001130127.1_53724001_1 - 2.3e-63 213.6 0.0 3.4e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ROK PF00480.18 001130127.1_53724001_1 - 0.091 12.1 0.0 0.65 9.3 0.0 2.3 3 0 0 3 3 3 0 ROK family DUF4381 PF14316.4 001130127.1_53724001_1 - 0.55 10.3 1.9 1.1 9.4 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Herpes_capsid PF06112.9 001157294.1_53722001_1 - 0.53 10.2 2.5 0.94 9.4 2.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Reticulon PF02453.15 001157294.1_53722001_2 - 4.3e-42 143.6 1.2 5.4e-42 143.3 1.2 1.1 1 0 0 1 1 1 1 Reticulon Kelch_5 PF13854.4 001157294.1_53722001_2 - 0.11 12.4 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Kelch motif peroxidase PF00141.21 001136651.2_53723001_1 - 1.9e-68 230.5 0.2 2.4e-68 230.1 0.2 1.1 1 0 0 1 1 1 1 Peroxidase zf-RING_2 PF13639.4 001152412.1_53725001_1 - 6.4e-13 48.6 4.8 2.3e-12 46.8 4.8 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001152412.1_53725001_1 - 1.5e-10 40.5 1.8 8.3e-10 38.1 1.2 2.6 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.20 001152412.1_53725001_1 - 3.5e-08 33.3 0.2 7.9e-08 32.2 0.2 1.6 1 1 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.4 001152412.1_53725001_1 - 7.4e-07 28.8 3.9 2.1e-06 27.3 3.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001152412.1_53725001_1 - 8.8e-07 28.6 2.2 2e-06 27.4 2.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001152412.1_53725001_1 - 1.5e-05 25.1 6.8 4.7e-05 23.5 6.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.4 001152412.1_53725001_1 - 6.2e-05 22.7 2.1 0.00016 21.4 2.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001152412.1_53725001_1 - 0.00016 21.5 3.3 0.00062 19.6 0.3 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.5 001152412.1_53725001_1 - 0.026 14.4 1.8 0.068 13.1 1.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MRP-L46 PF11788.6 001152469.1_53722001_1 - 0.019 15.5 2.3 0.59 10.8 0.4 2.6 2 1 1 3 3 3 0 39S mitochondrial ribosomal protein L46 Acyltransf_C PF16076.3 001152469.1_53722001_3 - 0.012 15.6 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Acyltransferase C-terminus Methyltransf_7 PF03492.13 001352045.1_53723001_3 - 1.2e-98 330.3 0.0 1.5e-98 329.9 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase MTS PF05175.12 001136766.1_53723001_2 - 2.4e-15 56.4 0.1 3.6e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.11 001136766.1_53723001_2 - 1e-12 47.9 0.3 1.6e-12 47.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.4 001136766.1_53723001_2 - 2.1e-10 40.5 0.1 3.1e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001136766.1_53723001_2 - 2.4e-10 40.9 0.1 4.1e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.16 001136766.1_53723001_2 - 9.5e-09 35.1 0.1 5.8e-08 32.5 0.2 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.10 001136766.1_53723001_2 - 1.6e-06 28.5 0.0 2.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.14 001136766.1_53723001_2 - 1.8e-05 24.4 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.8 001136766.1_53723001_2 - 2.6e-05 23.9 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.10 001136766.1_53723001_2 - 4.1e-05 24.1 0.0 7.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.13 001136766.1_53723001_2 - 0.00051 19.6 0.0 0.00074 19.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_32 PF13679.4 001136766.1_53723001_2 - 0.0031 17.4 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.16 001136766.1_53723001_2 - 0.0068 16.0 0.0 0.041 13.5 0.0 1.9 2 0 0 2 2 2 1 DNA methylase FmrO PF07091.9 001136766.1_53723001_2 - 0.0093 15.4 0.4 0.019 14.4 0.2 1.4 1 1 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_18 PF12847.5 001136766.1_53723001_2 - 0.014 15.2 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.9 001136766.1_53723001_2 - 0.034 12.9 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.16 001136766.1_53723001_2 - 0.051 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.15 001136766.1_53723001_2 - 0.053 12.8 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FYRC PF05965.12 001176517.1_53724001_1 - 2.5e-21 75.5 0.0 4.9e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.12 001176517.1_53724001_1 - 5.6e-09 35.6 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus EF-hand_1 PF00036.30 001147871.1_53724001_2 - 1.2e-17 61.9 13.5 0.0011 18.2 0.6 5.9 6 0 0 6 6 6 4 EF hand EF-hand_7 PF13499.4 001147871.1_53724001_2 - 1.5e-17 63.7 5.4 6.6e-08 32.8 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.4 001147871.1_53724001_2 - 8.7e-16 56.5 14.7 0.00077 18.7 0.7 6.1 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.4 001147871.1_53724001_2 - 3.5e-15 54.4 8.2 0.019 14.7 0.0 6.7 7 0 0 7 7 7 4 EF-hand domain EF-hand_8 PF13833.4 001147871.1_53724001_2 - 1.3e-10 40.8 11.0 0.0075 15.9 0.0 5.2 4 1 1 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001147871.1_53724001_2 - 2.2e-07 31.1 1.1 0.00014 22.0 0.0 3.3 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001147871.1_53724001_2 - 1.1 9.1 4.5 51 3.8 0.2 4.0 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand tRNA-synt_1d PF00750.17 001147878.1_53725001_3 - 6.3e-118 393.6 0.0 8.6e-118 393.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.13 001147878.1_53725001_3 - 1.1e-32 112.5 0.0 2.5e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.14 001147878.1_53725001_3 - 4.8e-17 62.2 0.0 1.4e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF5053 PF16476.3 001147878.1_53725001_3 - 0.087 12.4 1.2 8.2 6.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) Methyltransf_29 PF03141.14 001321640.1_53722001_1 - 1.1e-09 37.3 0.4 1.4e-09 37.0 0.4 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ras PF00071.20 001157651.2_53723001_1 - 6.5e-62 207.8 0.3 8.1e-62 207.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001157651.2_53723001_1 - 2.2e-34 118.2 0.1 3.1e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001157651.2_53723001_1 - 1.2e-11 44.3 0.1 1.7e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001157651.2_53723001_1 - 1.7e-06 28.0 0.1 2.7e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001157651.2_53723001_1 - 0.00066 19.5 0.1 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001157651.2_53723001_1 - 0.0021 17.3 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001157651.2_53723001_1 - 0.0026 17.2 0.5 0.0077 15.6 0.5 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.4 001157651.2_53723001_1 - 0.022 14.9 0.0 0.16 12.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain DLIC PF05783.9 001157651.2_53723001_1 - 0.042 12.6 0.0 0.063 12.0 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.4 001157651.2_53723001_1 - 0.074 13.3 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.25 001157651.2_53723001_1 - 0.097 13.0 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter FAD-SLDH PF12318.6 001157651.2_53723001_1 - 0.11 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase SRPRB PF09439.8 001157651.2_53723001_1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mito_fiss_reg PF05308.9 001157651.2_53723001_1 - 1.4 8.8 3.0 2.4 8.0 3.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase_Tyr PF07714.15 001352056.1_53727001_2 - 1.4e-25 90.0 0.0 2.7e-25 89.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001352056.1_53727001_2 - 5.4e-18 65.2 0.0 8.2e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.5 001352056.1_53727001_2 - 1.4e-13 50.6 3.9 0.0021 18.2 0.1 6.4 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001352056.1_53727001_2 - 3.2e-13 49.1 7.5 6.5e-08 32.1 0.4 4.7 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.31 001352056.1_53727001_2 - 1.4e-07 30.8 2.0 20 6.0 0.0 8.0 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.4 001352056.1_53727001_2 - 0.00075 19.2 5.7 42 4.4 0.1 6.9 8 0 0 8 8 8 0 Leucine Rich repeat zf-C2H2 PF00096.24 001152627.1_53725001_2 - 3.4e-07 30.2 9.2 0.007 16.6 0.3 3.8 2 1 1 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 001152627.1_53725001_2 - 1.3e-05 25.2 5.6 0.00011 22.2 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.4 001152627.1_53725001_2 - 0.00031 21.2 12.1 0.19 12.5 0.2 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.5 001152627.1_53725001_2 - 0.0012 19.0 5.5 0.0023 18.2 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001152627.1_53725001_2 - 0.075 12.9 0.2 0.075 12.9 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001152627.1_53725001_2 - 0.88 10.0 14.9 1.8 9.0 6.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zinc-ribbons_6 PF07191.10 001152627.1_53725001_2 - 0.97 9.3 7.7 2 8.4 4.9 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-Sec23_Sec24 PF04810.13 001152627.1_53725001_2 - 3.3 7.7 5.3 23 5.0 0.1 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Pkinase PF00069.23 001147953.1_53725001_2 - 4.1e-44 150.8 0.0 5.7e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001147953.1_53725001_2 - 4.4e-44 150.6 0.0 6.6e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WAK_assoc PF14380.4 001147953.1_53725001_2 - 4.8e-18 65.7 1.4 1.1e-17 64.5 1.4 1.6 1 0 0 1 1 1 1 Wall-associated receptor kinase C-terminal GUB_WAK_bind PF13947.4 001147953.1_53725001_2 - 0.00042 21.0 0.2 0.0012 19.5 0.2 1.8 1 0 0 1 1 1 1 Wall-associated receptor kinase galacturonan-binding APH PF01636.21 001147953.1_53725001_2 - 0.019 14.7 0.4 0.27 11.0 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Herpes_gE PF02480.14 001147953.1_53725001_2 - 0.11 11.0 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Serglycin PF04360.10 001147953.1_53725001_2 - 0.31 10.8 4.6 0.14 12.0 1.7 1.9 2 0 0 2 2 2 0 Serglycin HECT PF00632.23 001152732.1_53726001_1 - 1.2e-67 228.4 0.1 1.7e-67 227.9 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ubiquitin PF00240.21 001152732.1_53726001_1 - 1.7e-05 24.4 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L28e PF01778.15 001157796.1_53723001_3 - 5e-34 117.3 5.9 6.7e-34 116.9 5.9 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family KA1 PF02149.17 001176808.1_53723001_1 - 4.2e-14 51.9 0.1 1.9e-13 49.8 0.1 2.0 2 0 0 2 2 2 1 Kinase associated domain 1 AdenylateSensor PF16579.3 001176808.1_53723001_1 - 1.1e-06 29.0 0.7 1.7e-05 25.1 0.7 2.4 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase UBA PF00627.29 001176808.1_53723001_1 - 1.8e-05 24.4 0.2 3.4e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_2 PF08587.9 001176808.1_53723001_1 - 0.0013 18.7 0.3 0.0025 17.8 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) DUF3431 PF11913.6 001176808.1_53723001_1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) UBA_3 PF09288.8 001176808.1_53723001_1 - 0.09 12.5 0.8 0.17 11.6 0.2 1.7 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF561 PF04481.10 001150005.1_53723001_1 - 1.1e-85 286.6 0.2 1.6e-85 286.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF561) ThiG PF05690.12 001150005.1_53723001_1 - 1.9 7.6 7.0 1.6 7.8 5.4 1.7 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG IF-2 PF11987.6 001176861.2_53724001_3 - 1.7e-29 101.9 0.1 4.3e-29 100.6 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 CLASP_N PF12348.6 001148136.1_53724001_2 - 1e-07 31.7 0.1 1.5e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 CLASP N terminal Cnd1 PF12717.5 001148136.1_53724001_2 - 0.00033 20.6 1.4 0.099 12.5 0.3 2.5 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.18 001148136.1_53724001_2 - 0.0012 17.4 1.5 0.0084 14.6 1.5 1.9 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.4 001148136.1_53724001_2 - 0.0041 17.3 0.2 1.8 8.9 0.1 2.6 1 1 1 2 2 2 2 HEAT repeats UNC45-central PF11701.6 001148136.1_53724001_2 - 0.031 14.1 0.3 0.32 10.8 0.3 2.1 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central HEAT PF02985.20 001148136.1_53724001_2 - 0.036 14.1 4.8 6.2 7.2 0.1 3.9 5 0 0 5 5 5 0 HEAT repeat DUF4336 PF14234.4 001175798.2_53724001_2 - 1.1e-108 363.1 5.3 3e-87 292.6 0.5 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) PP2C PF00481.19 001152918.1_53725001_1 - 4.8e-36 124.6 0.0 7.2e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001152918.1_53725001_1 - 0.00099 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.10 001152918.1_53725001_1 - 0.095 12.5 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF2042 PF09743.7 001152918.1_53725001_1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) p450 PF00067.20 001152921.1_53724001_2 - 2.9e-88 296.5 0.0 3.5e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL PF00657.20 001137136.2_53724001_1 - 1e-08 35.2 0.0 6e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DEAD PF00270.27 001137156.1_53725001_2 - 5.2e-50 169.5 0.0 1e-49 168.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001137156.1_53725001_2 - 8.8e-34 116.1 0.0 1.3e-32 112.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.10 001137156.1_53725001_2 - 0.00034 19.4 0.0 0.042 12.5 0.0 2.8 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.13 001137156.1_53725001_2 - 0.006 16.5 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.3 001137156.1_53725001_2 - 0.11 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.4 001137156.1_53725001_2 - 0.12 12.5 0.1 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain CMS1 PF14617.4 001137156.1_53725001_2 - 0.14 11.3 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Glyco_hydro_17 PF00332.16 001148287.1_53724001_2 - 9.7e-72 241.9 0.0 1.2e-71 241.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001148287.1_53724001_2 - 7.7e-19 68.0 2.1 1.4e-18 67.2 2.1 1.4 1 0 0 1 1 1 1 X8 domain MACPF PF01823.17 001137201.1_53725001_1 - 7.6e-37 127.3 0.0 1e-36 126.9 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain IBR PF01485.19 001137234.1_53724001_2 - 4.9e-19 68.2 41.4 3.2e-12 46.3 2.7 3.9 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RVT_3 PF13456.4 001137234.1_53724001_2 - 1.2e-14 53.9 0.0 2.9e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like zf-RING_2 PF13639.4 001137234.1_53724001_2 - 0.00018 21.6 6.7 0.00018 21.6 6.7 3.6 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.23 001137234.1_53724001_2 - 0.00019 21.1 5.1 0.00019 21.1 5.1 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) VHS PF00790.17 001158115.1_53725001_1 - 3.2e-29 101.5 0.0 6.2e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.12 001158115.1_53725001_1 - 5.8e-17 61.6 0.8 5.8e-17 61.6 0.8 1.8 2 0 0 2 2 2 1 GAT domain M11L PF11099.6 001158115.1_53725001_1 - 0.0003 21.0 0.1 0.0079 16.4 0.0 2.1 2 0 0 2 2 2 1 Apoptosis regulator M11L like HEAT_2 PF13646.4 001158115.1_53725001_1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats ENTH PF01417.18 001158115.1_53725001_1 - 0.17 11.8 0.1 0.4 10.6 0.1 1.5 1 0 0 1 1 1 0 ENTH domain DUF393 PF04134.10 001153067.2_53723001_2 - 2.3e-28 99.6 0.0 4.3e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Pkinase PF00069.23 001153099.1_53724001_2 - 2.4e-46 158.1 0.0 3.2e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001153099.1_53724001_2 - 8.3e-45 152.9 0.0 1.1e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PRIMA1 PF16101.3 001153099.1_53724001_3 - 0.0055 16.6 1.4 0.0055 16.6 1.4 2.4 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 DA1-like PF12315.6 001137345.1_53725001_2 - 1.3e-97 325.0 0.1 1.9e-97 324.5 0.1 1.3 1 0 0 1 1 1 1 Protein DA1 LIM PF00412.20 001137345.1_53725001_2 - 5.7e-09 35.9 7.0 5.7e-09 35.9 7.0 3.5 2 1 1 3 3 3 2 LIM domain UIM PF02809.18 001137345.1_53725001_2 - 0.00011 21.8 5.8 0.18 11.7 2.9 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif CCDC50_N PF15295.4 001137345.1_53725001_2 - 0.058 13.4 1.2 0.11 12.6 1.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Paired_CXXCH_1 PF09699.8 001137345.1_53725001_2 - 2.3 7.9 12.2 2.6 7.8 1.4 3.3 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) Pkinase_Tyr PF07714.15 001137351.1_53724001_2 - 2.8e-44 151.2 0.0 4.3e-44 150.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001137351.1_53724001_2 - 8.8e-42 143.1 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.21 001137351.1_53724001_2 - 0.072 12.9 0.0 0.39 10.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family TFIIB PF00382.17 001148518.1_53725001_2 - 3e-28 97.5 0.2 4e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.11 001148518.1_53725001_2 - 5.4e-28 97.2 2.7 5.4e-28 97.2 2.7 2.3 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.10 001148518.1_53725001_2 - 0.13 11.6 6.1 0.4 10.1 6.1 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding Zip PF02535.20 001137393.1_53724001_2 - 1.9e-16 60.1 33.4 2.8e-13 49.7 7.6 3.8 1 1 1 3 3 3 3 ZIP Zinc transporter PAP2 PF01569.19 001153279.1_53724001_3 - 4.7e-31 107.3 1.0 4.7e-31 107.3 1.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.4 001153279.1_53724001_3 - 0.068 12.7 9.7 0.56 9.7 9.7 2.4 1 1 0 1 1 1 0 PAP2 superfamily PRAI PF00697.20 001148608.1_53723001_1 - 7.8e-35 120.3 0.0 9.6e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase P3A PF08727.9 001196238.1_53727001_1 - 0.17 11.1 0.1 19 4.6 0.1 2.4 2 0 0 2 2 2 0 Poliovirus 3A protein like HECT PF00632.23 001196238.1_53727001_2 - 1.1e-66 225.4 0.1 1.5e-66 224.9 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ubiquitin PF00240.21 001196238.1_53727001_2 - 2.7e-06 26.9 0.0 5.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Glyco_transf_43 PF03360.14 001158570.2_53725001_1 - 3.3e-57 193.5 1.2 1.1e-56 191.8 0.3 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 43 B3_4 PF03483.15 001153432.1_53725001_2 - 4e-28 98.1 0.0 7.2e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.13 001153432.1_53725001_2 - 1.3e-10 41.2 0.0 7.7e-09 35.6 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.18 001153432.1_53725001_2 - 4.7e-07 29.4 0.0 7.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) UQ_con PF00179.24 001137800.1_53722001_2 - 2.8e-53 179.2 0.0 4.5e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001137800.1_53722001_2 - 0.00018 21.7 2.0 0.0041 17.3 0.1 2.1 1 1 0 2 2 2 1 RWD domain Prok-E2_B PF14461.4 001137800.1_53722001_2 - 0.0003 20.3 0.0 0.0025 17.4 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic E2 family B UEV PF05743.11 001137800.1_53722001_2 - 0.079 12.7 0.0 0.079 12.7 0.0 2.0 2 0 0 2 2 2 0 UEV domain Vps4_C PF09336.8 001196460.1_53724001_1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain HMG_CoA_synt_C PF08540.8 001346654.1_53724001_3 - 2.7e-111 371.6 7.8 3.4e-111 371.2 7.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.15 001346654.1_53724001_3 - 2.5e-84 281.3 0.2 3.7e-84 280.8 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.8 001346654.1_53724001_3 - 1.9e-05 24.6 0.0 0.00035 20.5 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DNAP_B_exo_N PF08452.8 001346654.1_53724001_3 - 0.11 11.8 0.6 0.26 10.6 0.6 1.6 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal Myb_DNA-binding PF00249.29 001357723.1_53724001_2 - 1.4e-32 111.5 2.2 1.5e-15 56.9 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001357723.1_53724001_2 - 3.7e-22 78.2 1.6 5.5e-14 52.0 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001357723.1_53724001_2 - 0.00022 20.9 0.0 0.0028 17.4 0.0 2.2 1 1 1 2 2 2 1 Myb DNA-binding like Pkinase PF00069.23 001156444.2_53724001_2 - 3.7e-73 246.0 0.0 4.9e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001156444.2_53724001_2 - 2.4e-29 98.5 7.2 2e-08 33.1 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001156444.2_53724001_2 - 4e-26 91.2 4.0 1e-13 51.4 1.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.15 001156444.2_53724001_2 - 1.9e-25 89.5 0.0 2.7e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.4 001156444.2_53724001_2 - 3.5e-25 87.4 6.4 2.8e-10 39.7 0.4 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.4 001156444.2_53724001_2 - 9e-22 75.4 5.6 2.8e-06 26.4 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.4 001156444.2_53724001_2 - 5.3e-21 72.6 3.3 1e-05 24.9 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain SPARC_Ca_bdg PF10591.7 001156444.2_53724001_2 - 1.4e-07 31.7 0.1 0.014 15.6 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.21 001156444.2_53724001_2 - 9.2e-06 25.6 0.7 0.11 12.3 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family EF-hand_4 PF12763.5 001156444.2_53724001_2 - 0.00018 21.3 0.7 0.28 11.0 0.1 2.6 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.4 001156444.2_53724001_2 - 0.00022 20.5 0.0 0.0022 17.2 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Caleosin PF05042.11 001156444.2_53724001_2 - 0.00029 20.7 0.3 2 8.2 0.0 3.1 2 1 1 3 3 3 2 Caleosin related protein Kdo PF06293.12 001156444.2_53724001_2 - 0.00049 19.4 0.0 0.0012 18.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF615 PF04751.12 001156444.2_53724001_2 - 0.054 13.3 0.4 0.2 11.4 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF615) EFhand_Ca_insen PF08726.8 001156444.2_53724001_2 - 0.14 12.1 0.2 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Sec23_helical PF04815.13 001137891.1_53724001_1 - 3.2e-19 68.5 0.1 1.3e-18 66.6 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_trunk PF04811.13 001137891.1_53724001_1 - 3.4e-11 43.1 0.0 4.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.10 001137891.1_53724001_1 - 0.0018 18.9 0.0 0.0043 17.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain WD40 PF00400.30 001137899.1_53724001_3 - 2.3e-30 104.1 28.2 1.4e-07 31.9 0.4 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.10 001137899.1_53724001_3 - 4.6e-19 68.6 0.0 7.2e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.5 001137899.1_53724001_3 - 0.00014 22.0 0.9 0.51 10.5 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.9 001137899.1_53724001_3 - 0.0017 17.0 0.0 0.0029 16.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Serpin PF00079.18 001174184.1_53724001_2 - 2.2e-103 346.3 0.0 2.6e-103 346.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) PAP2 PF01569.19 001158740.1_53724001_1 - 9.5e-30 103.0 1.2 9.5e-30 103.0 1.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.4 001158740.1_53724001_1 - 0.0015 18.1 2.8 0.0065 16.0 2.8 2.0 1 1 0 1 1 1 1 PAP2 superfamily Ribosomal_L18A PF01775.15 001158755.2_53722001_3 - 5.4e-54 181.3 1.4 7.8e-54 180.8 1.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Lipase_GDSL PF00657.20 001358545.1_53723001_3 - 2.2e-08 34.2 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pectinesterase PF01095.17 001137980.1_53724001_1 - 4.7e-28 97.6 0.0 8.9e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Pectinesterase WG_beta_rep PF14903.4 001137980.1_53724001_1 - 0.073 13.2 0.9 2 8.7 0.1 2.6 2 0 0 2 2 2 0 WG containing repeat Myb_DNA-binding PF00249.29 001196713.1_53725001_3 - 9.2e-06 25.6 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001196713.1_53725001_3 - 0.00017 21.6 0.1 0.00064 19.8 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain FMN_dh PF01070.16 001158875.1_53723001_2 - 3.3e-135 450.5 0.2 3.8e-135 450.3 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.23 001158875.1_53723001_2 - 5.3e-08 32.1 0.2 2.9e-07 29.7 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.13 001158875.1_53723001_2 - 5.1e-07 29.2 0.3 8.9e-07 28.5 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.15 001158875.1_53723001_2 - 1.2e-05 24.5 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.12 001158875.1_53723001_2 - 7.5e-05 22.0 0.2 0.029 13.6 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.19 001158875.1_53723001_2 - 0.001 18.5 0.2 0.0045 16.3 0.0 2.2 2 1 1 3 3 3 1 Histidine biosynthesis protein TMP-TENI PF02581.15 001158875.1_53723001_2 - 0.011 14.9 0.1 0.18 11.0 0.1 2.3 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI DHO_dh PF01180.19 001158875.1_53723001_2 - 0.092 11.8 0.1 0.49 9.4 0.0 1.9 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase DUF561 PF04481.10 001158875.1_53723001_2 - 0.14 11.2 0.0 0.65 9.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF561) BTB PF00651.29 001158895.1_53723001_2 - 5.6e-26 90.8 0.3 6.6e-25 87.4 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.24 001158895.1_53723001_2 - 0.072 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 MATH domain LSM PF01423.20 001153695.1_53722001_1 - 2.8e-18 65.2 0.7 3.9e-18 64.8 0.7 1.2 1 0 0 1 1 1 1 LSM domain zf-RING_2 PF13639.4 001153781.1_53723001_1 - 4.2e-13 49.2 8.8 4.2e-13 49.2 8.8 1.7 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.5 001153781.1_53723001_1 - 1.1e-09 38.3 4.3 2.4e-09 37.2 4.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001153781.1_53723001_1 - 2.8e-09 36.4 4.5 6.7e-09 35.2 4.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001153781.1_53723001_1 - 3.3e-08 33.1 7.7 6e-08 32.3 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001153781.1_53723001_1 - 1.3e-06 28.1 7.2 2.5e-06 27.1 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001153781.1_53723001_1 - 0.00019 21.2 6.0 0.00035 20.3 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001153781.1_53723001_1 - 0.00033 20.5 7.3 0.00076 19.3 7.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.5 001153781.1_53723001_1 - 0.00052 19.9 2.2 0.001 19.0 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.4 001153781.1_53723001_1 - 0.00077 19.1 7.1 0.0015 18.2 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.6 001153781.1_53723001_1 - 0.006 16.6 6.0 0.015 15.3 6.0 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.5 001153781.1_53723001_1 - 0.068 13.2 8.5 0.12 12.4 8.5 1.4 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.3 001153781.1_53723001_1 - 0.075 12.5 6.0 0.16 11.5 6.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.12 001153781.1_53723001_1 - 0.1 12.1 5.0 0.25 10.9 5.0 1.7 1 0 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.4 001153781.1_53723001_1 - 0.14 11.9 7.3 0.35 10.6 7.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.9 001153781.1_53723001_1 - 0.42 10.8 6.5 1.1 9.5 6.5 1.8 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.4 001153781.1_53723001_1 - 0.91 9.2 7.6 9.4 5.9 8.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.4 001153781.1_53723001_1 - 1.4 8.8 5.3 0.68 9.8 1.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.27 001153781.1_53723001_1 - 2 8.2 6.0 4.7 7.0 6.0 1.7 1 0 0 1 1 1 0 PHD-finger Aminotran_3 PF00202.19 001349188.1_53724001_3 - 4e-92 308.8 0.1 5e-92 308.5 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SecE PF00584.18 001153836.1_53721001_3 - 2.4e-12 46.4 0.1 2.4e-12 46.4 0.1 2.1 2 0 0 2 2 2 1 SecE/Sec61-gamma subunits of protein translocation complex zf-met PF12874.5 001196921.1_53725001_1 - 3.3e-16 59.0 17.0 8.9e-08 32.2 1.2 4.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001196921.1_53725001_1 - 3.2e-12 46.3 5.2 3.1e-05 24.0 0.3 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.10 001196921.1_53725001_1 - 3.8e-07 30.3 2.5 0.0087 16.2 0.1 3.4 3 0 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.5 001196921.1_53725001_1 - 0.0016 18.6 13.0 0.02 15.1 0.1 3.9 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.10 001196921.1_53725001_1 - 0.0053 16.4 1.2 2.6 7.8 0.2 2.8 2 0 0 2 2 2 2 U1 zinc finger Vps36-NZF-N PF16988.3 001196921.1_53725001_1 - 0.045 13.0 0.9 1.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Neural_ProG_Cyt PF06567.9 001196921.1_53725001_1 - 0.22 11.6 1.5 0.37 10.9 0.3 1.9 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain zf-C2H2_4 PF13894.4 001196921.1_53725001_1 - 6.3 7.8 11.7 14 6.7 0.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger PHD PF00628.27 001196921.1_53725001_1 - 7.9 6.3 8.5 19 5.1 0.3 3.5 3 0 0 3 3 3 0 PHD-finger Ribosomal_S3Ae PF01015.16 001159102.2_53723001_3 - 4.2e-98 326.9 2.6 5.2e-98 326.6 2.6 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family MRP-L27 PF09809.7 001159102.2_53723001_3 - 0.054 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 TAXi_N PF14543.4 001138202.1_53724001_3 - 5.2e-47 160.3 1.3 7.2e-47 159.8 1.3 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.4 001138202.1_53724001_3 - 2.1e-36 125.0 0.0 3.1e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.21 001138202.1_53724001_3 - 2.5e-14 53.3 0.0 1.5e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease adh_short PF00106.23 001159142.1_53723001_1 - 3.5e-42 143.9 0.0 4.7e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001159142.1_53723001_1 - 5.3e-30 104.6 0.0 7.6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001159142.1_53723001_1 - 0.00013 21.9 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 KR domain potato_inhibit PF00280.16 001159158.2_53722001_1 - 1.4e-24 86.4 0.5 1.9e-24 86.0 0.5 1.2 1 0 0 1 1 1 1 Potato inhibitor I family ArfGap PF01412.16 001349829.1_53725001_1 - 1.1e-39 134.9 0.0 2.1e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SMP PF04927.10 001159171.1_53723001_2 - 6.1e-55 183.5 30.7 1.1e-19 70.5 9.6 3.4 3 0 0 3 3 3 3 Seed maturation protein Voltage_CLC PF00654.18 001350148.1_53727001_3 - 1.5e-72 244.6 32.5 1.4e-71 241.5 28.2 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.26 001350148.1_53727001_3 - 8.8e-12 45.2 0.0 3e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain p450 PF00067.20 001159622.1_53725001_1 - 1.8e-78 264.2 0.0 2.5e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 eRF1_2 PF03464.13 001154114.1_53724001_3 - 3e-41 140.7 0.0 4.9e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.13 001154114.1_53724001_3 - 8.5e-35 119.5 0.1 1.4e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.13 001154114.1_53724001_3 - 7.6e-20 71.1 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Actin PF00022.17 001154181.1_53724001_2 - 6.5e-78 262.0 0.0 1.7e-76 257.4 0.0 2.0 1 1 0 1 1 1 1 Actin DnaJ PF00226.29 001154252.1_53723001_1 - 1.7e-18 66.4 0.1 2.7e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain RES PF08808.9 001165808.1_53723001_1 - 0.032 14.0 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 RES domain Transposase_24 PF03004.12 001165808.1_53723001_2 - 0.0062 16.5 0.3 0.0062 16.5 0.3 1.6 2 0 0 2 2 2 1 Plant transposase (Ptta/En/Spm family) HALZ PF02183.16 001165808.1_53723001_2 - 0.1 12.6 1.8 0.21 11.7 1.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Ribosomal_L36e PF01158.16 001297629.1_53722001_3 - 7.7e-42 141.3 7.3 9.8e-42 141.0 7.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Arm PF00514.21 001349834.1_53725001_2 - 2.9e-90 293.8 16.9 9.5e-13 47.6 0.0 9.8 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.4 001349834.1_53725001_2 - 7e-25 86.9 0.8 4.9e-08 33.1 0.0 5.8 4 1 1 5 5 5 4 HEAT-like repeat IBB PF01749.18 001349834.1_53725001_2 - 2.4e-23 82.2 0.3 6.5e-23 80.8 0.2 1.8 2 0 0 2 2 1 1 Importin beta binding domain HEAT_2 PF13646.4 001349834.1_53725001_2 - 3.3e-21 75.3 0.1 1.3e-05 25.4 0.0 6.6 3 2 3 7 7 7 5 HEAT repeats Arm_3 PF16186.3 001349834.1_53725001_2 - 9.9e-20 69.7 0.7 2.1e-19 68.7 0.7 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.20 001349834.1_53725001_2 - 2e-14 52.2 3.3 0.0014 18.6 0.0 8.4 9 0 0 9 9 9 2 HEAT repeat Arm_2 PF04826.11 001349834.1_53725001_2 - 4.1e-08 32.9 0.4 0.095 12.0 0.2 3.3 3 0 0 3 3 3 3 Armadillo-like Atx10homo_assoc PF09759.7 001349834.1_53725001_2 - 9.6e-08 31.9 0.3 0.15 12.0 0.7 3.6 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.6 001349834.1_53725001_2 - 7.6e-06 25.9 0.4 2.2 8.3 0.0 4.8 5 1 0 5 5 5 1 V-ATPase subunit H NopRA1 PF16201.3 001349834.1_53725001_2 - 8.9e-06 25.3 0.0 0.3 10.5 0.0 3.9 3 1 0 3 3 3 2 Nucleolar pre-ribosomal-associated protein 1 HEAT_PBS PF03130.14 001349834.1_53725001_2 - 0.0035 17.7 0.2 8.9 7.2 0.0 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat CTNNBL PF08216.9 001349834.1_53725001_2 - 0.02 14.9 0.6 31 4.7 0.0 4.1 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.9 001349834.1_53725001_2 - 0.03 13.5 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Mo25-like RICTOR_V PF14668.4 001349834.1_53725001_2 - 0.037 14.1 4.4 7 6.8 0.1 4.4 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 NAM PF02365.13 001321495.1_53723001_2 - 1e-14 55.0 0.1 1.6e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein SET PF00856.26 001138624.1_53724001_3 - 4.6e-06 27.0 0.0 8.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Copine PF07002.14 001174250.1_53725001_3 - 4.1e-79 264.9 0.0 6.1e-79 264.4 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.28 001174250.1_53725001_3 - 1.5e-21 76.5 0.1 1.8e-09 37.7 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.7 001174250.1_53725001_3 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Lipase_GDSL PF00657.20 001352154.1_53723001_2 - 1.1e-09 38.5 0.0 1.4e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aminotran_3 PF00202.19 001346846.1_53724001_3 - 9.5e-113 376.8 0.0 1.3e-112 376.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.19 001346846.1_53724001_3 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 2 0 0 2 2 2 0 Aminotransferase class I and II DUF1644 PF07800.10 001301578.1_53723001_1 - 1e-62 211.0 6.0 1.6e-62 210.4 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) zf-C3HC4_3 PF13920.4 001301578.1_53723001_1 - 0.036 13.8 9.5 0.22 11.3 3.0 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF1076 PF06416.10 001301578.1_53723001_1 - 0.053 13.3 1.7 0.055 13.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1076) EF-hand_1 PF00036.30 001174275.1_53722001_1 - 2e-30 101.9 9.3 1e-08 34.0 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001174275.1_53722001_1 - 3.5e-27 94.5 3.6 1.6e-14 54.0 2.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001174275.1_53722001_1 - 3.2e-24 84.3 9.2 2.6e-09 36.5 2.1 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.4 001174275.1_53722001_1 - 6.3e-23 78.6 4.1 1.8e-06 27.3 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.4 001174275.1_53722001_1 - 1.1e-22 78.3 6.4 2.8e-06 26.5 0.2 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.7 001174275.1_53722001_1 - 6.7e-06 26.3 0.3 0.092 12.9 0.0 2.6 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001174275.1_53722001_1 - 3.9e-05 23.4 1.6 0.18 11.7 0.2 2.8 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.11 001174275.1_53722001_1 - 0.00014 21.7 0.3 1.3 8.8 0.0 3.1 2 1 1 3 3 3 2 Caleosin related protein EF-hand_9 PF14658.4 001174275.1_53722001_1 - 0.00021 21.4 0.1 0.044 14.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain AAA_assoc_2 PF16193.3 001174275.1_53722001_1 - 0.061 13.5 0.1 0.98 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA C-terminal domain EF-hand_11 PF08976.9 001174275.1_53722001_1 - 0.071 13.9 0.0 1.2 9.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF615 PF04751.12 001174275.1_53722001_1 - 0.14 11.9 0.3 0.28 11.0 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF615) SSrecog PF03531.12 001351042.1_53725001_1 - 1.9e-74 249.6 0.0 2.7e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.10 001351042.1_53725001_1 - 9.7e-24 83.5 0.0 2.4e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like HMG_box PF00505.17 001351042.1_53725001_1 - 9.1e-20 70.7 4.4 1.9e-19 69.7 4.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001351042.1_53725001_1 - 1.3e-11 44.8 5.1 2.8e-11 43.7 5.1 1.6 1 0 0 1 1 1 1 HMG-box domain YL1 PF05764.11 001351042.1_53725001_1 - 0.028 14.4 18.5 0.045 13.8 18.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.12 001351042.1_53725001_1 - 0.15 10.2 10.3 0.24 9.6 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein YABBY PF04690.11 001351042.1_53725001_1 - 0.42 11.0 2.8 0.86 10.0 2.8 1.5 1 0 0 1 1 1 0 YABBY protein DNA_pol_phi PF04931.11 001351042.1_53725001_1 - 0.53 8.2 5.3 0.78 7.7 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi GARS_A PF01071.17 001154436.2_53725001_1 - 2.1e-81 272.2 0.2 3e-81 271.7 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.13 001154436.2_53725001_1 - 1.9e-29 102.1 0.0 3.8e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.14 001154436.2_53725001_1 - 3e-27 94.6 0.3 7.8e-27 93.2 0.3 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATPgrasp_Ter PF15632.4 001154436.2_53725001_1 - 0.00035 19.2 0.0 0.0007 18.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.15 001154436.2_53725001_1 - 0.00046 19.6 0.1 0.00098 18.5 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.12 001154436.2_53725001_1 - 0.0007 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.20 001154436.2_53725001_1 - 0.0012 18.3 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.4 001154436.2_53725001_1 - 0.018 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.8 001154436.2_53725001_1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Sec20 PF03908.11 001138730.1_53724001_2 - 4.8e-07 29.5 4.9 1.1e-06 28.3 1.5 2.5 2 0 0 2 2 2 1 Sec20 V-SNARE_C PF12352.6 001138730.1_53724001_2 - 0.00013 22.0 4.3 0.00019 21.5 1.6 2.5 3 0 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Exonuc_VII_L PF02601.13 001138730.1_53724001_2 - 0.006 16.1 0.5 0.1 12.0 0.5 2.1 1 1 0 1 1 1 1 Exonuclease VII, large subunit DUF3896 PF13035.4 001138730.1_53724001_2 - 0.044 13.8 1.4 3.7 7.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Tweety PF04906.11 001138730.1_53724001_2 - 0.12 10.8 3.9 0.11 11.0 0.8 1.9 2 0 0 2 2 2 0 Tweety MCPsignal PF00015.19 001138730.1_53724001_2 - 0.18 11.4 11.3 0.15 11.7 5.4 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Vps53_N PF04100.10 001138730.1_53724001_2 - 0.21 10.4 9.4 0.45 9.3 4.8 2.1 2 0 0 2 2 2 0 Vps53-like, N-terminal Occludin_ELL PF07303.11 001138730.1_53724001_2 - 0.21 12.2 0.2 0.21 12.2 0.2 2.7 3 1 0 3 3 3 0 Occludin homology domain DUF948 PF06103.9 001138730.1_53724001_2 - 0.21 11.7 15.3 1.9 8.7 0.0 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MutS_III PF05192.16 001138730.1_53724001_2 - 0.63 10.1 4.0 0.99 9.5 4.0 1.2 1 0 0 1 1 1 0 MutS domain III Laminin_II PF06009.10 001138730.1_53724001_2 - 0.71 9.8 10.7 0.8 9.6 0.9 2.3 2 0 0 2 2 2 0 Laminin Domain II Prominin PF05478.9 001138730.1_53724001_2 - 1.3 6.7 8.2 2.7 5.7 8.2 1.4 1 1 0 1 1 1 0 Prominin Synaptobrevin PF00957.19 001138730.1_53724001_2 - 2.6 7.8 9.9 0.96 9.2 4.1 2.3 2 0 0 2 2 2 0 Synaptobrevin PCRF PF03462.16 001138730.1_53724001_2 - 7.3 6.3 8.1 1.1 8.9 1.2 2.1 2 0 0 2 2 2 0 PCRF domain MCU PF04678.11 001138730.1_53724001_2 - 8.5 6.3 9.4 1.7 8.6 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF1771 PF08590.8 001154499.1_53725001_2 - 1e-16 60.9 9.2 1e-16 60.9 9.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.19 001154499.1_53725001_2 - 2.3e-05 24.5 0.2 5.7e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Smr domain PAM2 PF07145.13 001154499.1_53725001_2 - 3.2e-05 23.2 3.0 8.9e-05 21.8 1.2 2.5 2 0 0 2 2 2 1 Ataxin-2 C-terminal region Pkinase PF00069.23 001154503.2_53725001_1 - 5.4e-41 140.6 0.0 8.6e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001154503.2_53725001_1 - 2.2e-40 138.5 0.0 2.9e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.4 001154503.2_53725001_1 - 2.5e-14 52.6 12.3 3.2e-07 29.9 3.3 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRRNT_2 PF08263.10 001154503.2_53725001_1 - 7.2e-14 51.7 0.9 1.8e-13 50.4 0.9 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001154503.2_53725001_1 - 1.9e-10 40.7 12.6 1.1e-06 28.7 1.9 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001154503.2_53725001_1 - 7.3e-05 22.6 14.3 1.2 9.7 0.0 6.3 5 1 0 5 5 5 2 Leucine Rich Repeat TMEM190 PF15431.4 001154503.2_53725001_1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 190 SKG6 PF08693.8 001154503.2_53725001_1 - 0.15 11.3 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ABC2_membrane PF01061.22 001154517.2_53726001_2 - 1.4e-34 119.2 17.1 1.4e-34 119.2 17.1 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.25 001154517.2_53726001_2 - 3.4e-25 89.0 0.0 4.9e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.4 001154517.2_53726001_2 - 1.8e-06 27.9 0.6 0.011 15.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.4 001154517.2_53726001_2 - 0.00038 20.7 0.3 0.00066 20.0 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.5 001154517.2_53726001_2 - 0.0015 17.6 11.8 0.0023 17.0 11.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.4 001154517.2_53726001_2 - 0.0059 16.2 0.8 0.013 15.1 0.3 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.4 001154517.2_53726001_2 - 0.0062 16.0 0.2 0.071 12.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.14 001154517.2_53726001_2 - 0.065 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF87 PF01935.15 001154517.2_53726001_2 - 0.19 11.6 1.1 0.31 10.9 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 SMC_N PF02463.17 001154517.2_53726001_2 - 0.22 10.8 0.0 15 4.8 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Usp PF00582.24 001358895.1_53722001_2 - 0.0014 19.0 0.9 0.0065 16.8 0.9 2.1 1 1 0 1 1 1 1 Universal stress protein family Pyridoxal_deC PF00282.17 001174470.1_53724001_3 - 7.7e-108 360.4 0.0 1e-107 360.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.17 001174470.1_53724001_3 - 0.00044 19.2 0.0 0.00065 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase PF00069.23 001154603.1_53724001_2 - 7.1e-24 84.4 0.0 1.9e-22 79.8 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001154603.1_53724001_2 - 8.6e-10 38.2 0.0 1.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001154603.1_53724001_2 - 0.0016 18.3 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.4 001154603.1_53724001_2 - 0.0018 17.8 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.12 001154603.1_53724001_2 - 0.026 13.7 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FtsJ PF01728.17 001174581.1_53723001_1 - 5.8e-51 173.0 0.0 8e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.6 001174581.1_53723001_1 - 7.3e-15 55.0 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) DUF3381 PF11861.6 001174581.1_53723001_3 - 1.1e-08 35.0 0.6 1.5e-08 34.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) DUF3675 PF12428.6 001138937.1_53723001_1 - 1.4e-27 96.5 0.2 2.5e-27 95.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3675) RINGv PF12906.5 001138937.1_53723001_1 - 1.1e-11 44.5 15.4 2.3e-11 43.5 15.4 1.5 1 0 0 1 1 1 1 RING-variant domain Potyvirid-P3 PF13608.4 001138937.1_53723001_1 - 0.054 12.4 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF1270 PF06900.9 001138937.1_53723001_1 - 5.4 7.3 5.7 0.57 10.5 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) eIF-5_eIF-2B PF01873.15 001138988.1_53723001_1 - 1.2e-40 137.9 1.7 2e-40 137.2 0.0 2.1 3 0 0 3 3 3 1 Domain found in IF2B/IF5 Yqai PF09466.8 001138988.1_53723001_1 - 0.029 14.5 0.6 0.44 10.8 0.4 2.4 2 0 0 2 2 2 0 Hypothetical protein Yqai Acyltransferase PF01553.19 001291686.1_53725001_2 - 3.2e-06 26.7 0.0 8.7e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase EF-hand_7 PF13499.4 001291686.1_53725001_3 - 5.3e-09 36.3 2.4 2e-05 24.8 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001291686.1_53725001_3 - 6.7e-09 35.2 2.2 8.7e-06 25.3 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.30 001291686.1_53725001_3 - 4.9e-08 31.8 5.1 0.00012 21.2 1.3 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.4 001291686.1_53725001_3 - 5.2e-07 29.0 6.2 0.00012 21.6 0.6 3.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.4 001291686.1_53725001_3 - 0.98 8.9 4.7 0.41 10.1 0.5 2.5 3 0 0 3 3 3 0 EF hand Acid_phosphat_B PF03767.12 001154824.1_53723001_1 - 6.8e-63 212.2 0.0 8.6e-63 211.9 0.0 1.0 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase PF00702.24 001154824.1_53723001_1 - 0.00097 19.3 0.0 0.0014 18.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3649 PF12365.6 001154851.1_53722001_1 - 0.051 13.1 1.7 0.12 11.9 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) Ribosomal_L7Ae PF01248.24 001154851.1_53722001_2 - 7.1e-29 99.3 2.5 1e-28 98.8 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cornichon PF03311.12 001154931.1_53723001_3 - 3.3e-38 130.6 10.9 3.3e-38 130.6 10.9 1.5 2 0 0 2 2 2 1 Cornichon protein PMT_4TMC PF16192.3 001154931.1_53723001_3 - 0.3 10.5 12.7 0.018 14.5 7.4 1.6 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase EMP24_GP25L PF01105.22 001154931.1_53723001_3 - 0.73 9.6 2.6 0.39 10.5 0.5 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF563 PF04577.12 001323502.2_53725001_2 - 5.1e-13 49.5 0.0 8.7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Nop53 PF07767.9 001155008.1_53723001_3 - 3.3e-64 217.6 14.1 3.3e-64 217.6 14.1 2.2 2 0 0 2 2 2 2 Nop53 (60S ribosomal biogenesis) IGPD PF00475.16 001139320.1_53724001_1 - 5.6e-16 59.0 0.2 9.3e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase IGPD PF00475.16 001139320.1_53724001_3 - 1.4e-40 138.8 0.0 9.3e-40 136.1 0.0 2.1 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase WD40 PF00400.30 001139363.1_53724001_1 - 7.4e-26 89.8 17.8 0.00015 22.3 2.4 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001139363.1_53724001_1 - 2.6e-17 62.8 0.0 0.006 16.7 0.0 6.2 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PSII_BNR PF14870.4 001139363.1_53724001_1 - 0.0021 17.3 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 Photosynthesis system II assembly factor YCF48 PD40 PF07676.10 001139363.1_53724001_1 - 0.026 14.3 0.2 14 5.7 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF4863 PF16155.3 001155121.1_53723001_2 - 0.14 11.9 0.2 0.22 11.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) Methyltransf_2 PF00891.16 001155121.1_53723001_3 - 9.6e-65 217.8 0.0 1.4e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.9 001155121.1_53723001_3 - 1.5e-15 56.8 0.1 3e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.3 001155121.1_53723001_3 - 0.003 17.4 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Ank_2 PF12796.5 001320521.1_53724001_1 - 1.5e-34 118.3 10.9 1.5e-19 70.2 0.7 3.8 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.28 001320521.1_53724001_1 - 4e-31 105.9 17.6 3e-06 27.3 1.1 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.4 001320521.1_53724001_1 - 1.7e-30 104.9 7.1 6.6e-14 51.9 0.2 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.4 001320521.1_53724001_1 - 2.9e-29 100.5 27.7 1.8e-08 34.4 0.1 6.8 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.4 001320521.1_53724001_1 - 1.6e-23 80.1 8.4 9.6e-05 22.4 0.2 6.5 6 0 0 6 6 6 4 Ankyrin repeat zf-C3HC4_3 PF13920.4 001320521.1_53724001_1 - 1.1e-05 25.0 7.8 1.1e-05 25.0 7.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001320521.1_53724001_1 - 0.00063 19.4 9.3 0.0017 18.1 9.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001320521.1_53724001_1 - 0.014 15.5 9.3 0.04 14.0 9.3 1.9 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.4 001320521.1_53724001_1 - 0.39 10.5 9.8 2.2 8.1 9.8 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 001320521.1_53724001_1 - 1.1 9.2 7.2 3 7.8 7.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.4 001320521.1_53724001_1 - 3.9 7.4 8.6 10 6.0 8.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain WRKY PF03106.13 001322853.1_53723001_2 - 5.5e-24 84.2 2.3 8.4e-24 83.6 2.3 1.3 1 0 0 1 1 1 1 WRKY DNA -binding domain FAR1 PF03101.13 001322853.1_53723001_2 - 0.025 15.2 0.0 0.043 14.4 0.0 1.3 1 0 0 1 1 1 0 FAR1 DNA-binding domain Sugar_tr PF00083.22 001155307.1_53724001_2 - 1.5e-93 314.0 29.5 1.8e-93 313.7 29.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001155307.1_53724001_2 - 7.8e-23 80.8 29.2 7.8e-23 80.8 29.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Exo_endo_phos PF03372.21 001351740.1_53725001_3 - 1.7e-06 28.1 0.0 3.6e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ran_BP1 PF00638.16 001155432.1_53723001_2 - 4.4e-44 149.5 0.8 7e-44 148.9 0.8 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.21 001155432.1_53723001_2 - 0.00038 20.2 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 WH1 domain Asn_synthase PF00733.19 001291791.1_53725001_2 - 4.5e-98 329.0 0.1 8e-58 196.7 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.4 001291791.1_53725001_2 - 1.6e-42 144.2 0.0 2.5e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001291791.1_53725001_2 - 9.4e-34 116.4 0.0 1.7e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.6 001291791.1_53725001_2 - 1.5e-12 47.3 0.1 4.4e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.15 001291791.1_53725001_2 - 0.047 12.7 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD synthase EF-hand_1 PF00036.30 001111985.2_53722001_3 - 2.5e-40 132.9 11.5 8.9e-10 37.3 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001111985.2_53722001_3 - 2.1e-34 117.7 3.5 1.4e-17 63.7 1.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001111985.2_53722001_3 - 9.1e-30 102.1 9.0 3.2e-14 52.3 0.4 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.4 001111985.2_53722001_3 - 6.5e-29 97.2 6.5 4.9e-09 35.3 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001111985.2_53722001_3 - 9.3e-25 84.9 8.5 3.7e-06 26.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001111985.2_53722001_3 - 1.6e-15 57.0 0.2 6.5e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001111985.2_53722001_3 - 1.5e-08 34.4 0.7 0.00017 21.3 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001111985.2_53722001_3 - 7.3e-08 32.6 0.2 0.0049 17.1 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001111985.2_53722001_3 - 5.7e-05 23.8 0.1 0.0014 19.4 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.11 001111985.2_53722001_3 - 0.00013 21.8 0.1 0.13 12.2 0.0 2.7 3 1 0 3 3 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.8 001111985.2_53722001_3 - 0.00059 19.8 0.8 0.0019 18.1 0.3 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.14 001111985.2_53722001_3 - 0.0019 18.4 0.3 2.4 8.4 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb4 DUF3349 PF11829.6 001111985.2_53722001_3 - 0.0057 17.3 0.4 2.2 9.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.11 001111985.2_53722001_3 - 0.0082 15.9 0.2 1.3 8.8 0.0 2.8 1 1 2 3 3 3 1 Caleosin related protein MotA_activ PF09114.8 001111985.2_53722001_3 - 0.026 14.5 0.1 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain TerB PF05099.11 001111985.2_53722001_3 - 0.03 14.2 0.5 6.8 6.5 0.1 2.4 1 1 1 2 2 2 0 Tellurite resistance protein TerB Syntaxin PF00804.23 001111985.2_53722001_3 - 0.058 12.9 0.0 5.7 6.4 0.1 2.1 2 0 0 2 2 2 0 Syntaxin Poly_export PF02563.14 001111985.2_53722001_3 - 0.093 12.8 0.0 3 8.0 0.0 2.6 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.4 001111985.2_53722001_3 - 0.11 12.3 1.0 2.1 8.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain GPHH PF16905.3 001111985.2_53722001_3 - 0.11 12.2 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Fer2 PF00111.25 001111367.2_53723001_1 - 2.1e-18 65.9 0.1 3.6e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Gln-synt_C PF00120.22 001111973.2_53724001_2 - 1.7e-17 63.4 0.0 1.7e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001111973.2_53724001_2 - 9.8e-13 47.5 0.0 1.7e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.22 001305868.1_53724001_2 - 1.6e-17 63.4 0.0 1.7e-16 60.1 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001305868.1_53724001_2 - 2.1e-07 30.4 0.0 6.7e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain E1_dh PF00676.18 147700.1_53728120_1 - 0.00086 18.2 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Exo_endo_phos PF03372.21 147700.1_53728120_2 - 7.2e-06 26.1 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spc97_Spc98 PF04130.11 147700.1_53728120_3 - 4.1e-15 55.4 0.0 6e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Transket_pyr PF02779.22 147700.1_53728120_3 - 0.013 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain E1_dh PF00676.18 147700.1_53728120_3 - 0.031 13.1 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component S4 PF01479.23 151612.1_53726120_1 - 0.00052 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4e PF00900.18 151612.1_53726120_2 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal family S4e YTH PF04146.13 146398.1_53726120_1 - 2e-32 111.3 0.5 3e-32 110.7 0.5 1.2 1 0 0 1 1 1 1 YT521-B-like domain zf-UBP PF02148.17 146398.1_53726120_2 - 0.0014 18.8 0.1 0.0038 17.4 0.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein PDT PF00800.16 146398.1_53726120_3 - 2e-18 66.7 0.0 3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase NB-ARC PF00931.20 144557.1_53723120_2 - 0.014 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_13 PF13166.4 144557.1_53723120_2 - 0.029 12.9 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.4 144557.1_53723120_2 - 0.03 14.7 0.0 0.049 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.25 144557.1_53723120_2 - 0.039 14.3 0.1 0.085 13.2 0.0 1.5 2 0 0 2 2 2 0 ABC transporter AAA PF00004.27 144557.1_53723120_2 - 0.048 14.0 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.16 144557.1_53723120_2 - 0.11 12.3 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DOG1 PF14144.4 148744.1_53729120_2 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Seed dormancy control Ribosomal_S24e PF01282.17 148744.1_53729120_3 - 0.017 15.0 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S24e DOG1 PF14144.4 148745.1_53727120_2 - 6.6e-09 35.7 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Seed dormancy control Ribosomal_S24e PF01282.17 148745.1_53727120_3 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e DOG1 PF14144.4 148746.1_53722120_2 - 5.3e-09 36.0 0.3 3.1e-08 33.6 0.1 2.2 2 1 0 2 2 2 1 Seed dormancy control Ribosomal_S24e PF01282.17 148746.1_53722120_3 - 0.00081 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e Glyco_transf_10 PF00852.17 151643.1_53723120_1 - 1.4e-13 50.9 0.1 2e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Acetyltransf_1 PF00583.23 147834.1_53724120_1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.16 147834.1_53724120_1 - 0.036 13.6 0.2 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 MOZ/SAS family Acetyltransf_7 PF13508.5 147834.1_53724120_1 - 0.049 13.9 0.0 0.088 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RRS1 PF04939.10 147834.1_53724120_2 - 0.00082 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Methyltransf_16 PF10294.7 147834.1_53724120_2 - 0.21 11.2 0.1 0.31 10.6 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase p450 PF00067.20 146337.1_53724120_2 - 3.9e-20 71.9 0.0 5.3e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 146337.1_53724120_3 - 2.5e-41 141.8 0.0 5.1e-29 101.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Complex1_LYR PF05347.13 148498.1_53723120_2 - 8.2e-10 38.5 3.1 1.3e-09 37.8 3.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.4 148498.1_53723120_2 - 0.019 15.6 0.8 0.032 14.9 0.8 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Ribosomal_L37e PF01907.17 148424.1_53724120_1 - 3.4e-17 62.2 8.9 3.4e-17 62.2 8.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L37e DUF1230 PF06799.9 146319.1_53722120_1 - 3.9e-29 101.5 0.0 1.2e-28 99.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1230) DUF3700 PF12481.6 148547.1_53722120_2 - 0.0017 17.7 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Aluminium induced protein DUF3700 PF12481.6 148547.1_53722120_3 - 0.00032 20.0 0.1 0.0082 15.4 0.0 2.0 2 0 0 2 2 2 2 Aluminium induced protein TRAUB PF08164.10 146501.1_53729120_2 - 0.0001 22.6 0.1 0.00017 21.9 0.1 1.3 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal OPT PF03169.13 146501.1_53729120_3 - 1.8e-18 66.4 5.3 2.5e-18 65.9 5.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_35 PF01301.17 146501.1_53729120_3 - 9.4e-10 38.5 0.8 1.4e-09 37.9 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 AAA_11 PF13086.4 147944.1_53725120_2 - 2.3e-30 106.1 0.0 5.8e-30 104.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.4 147944.1_53725120_3 - 3.4e-25 88.7 0.0 5e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain PPR PF01535.18 148529.1_53724120_1 - 0.042 14.0 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 PPR repeat RIBIOP_C PF04950.10 148428.1_53726120_1 - 8e-25 87.7 0.0 1.3e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal YTH PF04146.13 148428.1_53726120_1 - 0.00011 21.8 0.1 0.00019 21.0 0.1 1.3 1 0 0 1 1 1 1 YT521-B-like domain RIBIOP_C PF04950.10 148429.1_53727120_1 - 0.0095 15.3 0.1 0.027 13.8 0.0 1.6 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal RIBIOP_C PF04950.10 148429.1_53727120_2 - 0.011 15.0 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal RIBIOP_C PF04950.10 148429.1_53727120_3 - 7.9e-21 74.6 0.2 7.8e-18 64.8 0.0 2.2 2 0 0 2 2 2 2 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal YTH PF04146.13 148429.1_53727120_3 - 0.00014 21.3 0.1 0.00023 20.7 0.1 1.3 1 0 0 1 1 1 1 YT521-B-like domain Nsp3_PL2pro PF12124.6 147952.1_53724120_2 - 0.0049 16.5 0.0 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 Coronavirus polyprotein cleavage domain Dimer_Tnp_hAT PF05699.12 147952.1_53724120_3 - 1.1e-25 89.1 0.0 1.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.4 147952.1_53724120_3 - 5e-07 29.8 0.1 8.2e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) SMP PF04927.10 135647.1_53722120_1 - 7.2e-06 26.3 9.1 7.2e-06 26.3 9.1 2.2 2 0 0 2 2 2 1 Seed maturation protein SMP PF04927.10 135647.1_53722120_2 - 0.0066 16.8 7.1 0.0066 16.8 7.1 1.6 2 0 0 2 2 2 1 Seed maturation protein SMP PF04927.10 135647.1_53722120_3 - 0.0014 19.0 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 Seed maturation protein Glyco_transf_43 PF03360.14 147023.1_53726120_1 - 3.3e-15 56.3 0.0 4.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 PLDc_2 PF13091.4 147023.1_53726120_1 - 5.7e-08 32.6 0.3 9.2e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.20 147023.1_53726120_1 - 1.7e-07 31.0 0.2 3.4e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc PF00614.20 147023.1_53726120_3 - 8.8e-08 31.9 0.2 1.5e-07 31.2 0.2 1.4 1 0 0 1 1 1 1 Phospholipase D Active site motif zf-MYND PF01753.16 148406.1_53723120_1 - 1.1e-06 28.5 16.5 3.1e-06 27.0 16.5 1.9 1 0 0 1 1 1 1 MYND finger DUF247 PF03140.13 148406.1_53723120_3 - 0.0042 16.4 0.0 0.0061 15.8 0.0 1.1 1 0 0 1 1 1 1 Plant protein of unknown function Kinesin PF00225.21 146338.1_53725120_3 - 1.4e-34 119.4 0.0 2e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.3 146338.1_53725120_3 - 2.7e-23 82.5 0.0 2.9e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 Microtubule binding Hydrolase_4 PF12146.6 146583.1_53723120_2 - 1e-09 37.9 0.0 5.3e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.18 146583.1_53723120_2 - 1.9e-07 30.9 0.0 4.7e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 146583.1_53723120_2 - 1.5e-06 28.9 0.0 2.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.10 146583.1_53723120_2 - 0.00011 22.1 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) BAAT_C PF08840.9 146583.1_53723120_2 - 0.00018 21.4 0.0 0.0031 17.3 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.18 146583.1_53723120_2 - 0.0039 17.2 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain LIDHydrolase PF10230.7 146583.1_53723120_2 - 0.0051 16.3 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.11 146583.1_53723120_2 - 0.022 14.5 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF702 PF05142.10 148025.1_53722120_3 - 7.2e-20 71.9 0.0 1.5e-19 70.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF702) DUF2701 PF10857.6 148211.1_53723120_1 - 0.22 11.5 0.8 0.44 10.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) Coprogen_oxidas PF01218.16 148449.1_53723120_2 - 4.7e-82 274.9 0.0 6e-82 274.5 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Coprogen_oxidas PF01218.16 148449.1_53723120_3 - 2.2e-44 151.2 0.0 3.1e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Pollen_allerg_1 PF01357.19 151596.1_53724120_3 - 0.057 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Pollen allergen Zinicin_2 PF10103.7 151777.1_53722120_2 - 0.034 13.3 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Zinicin-like metallopeptidase PPR PF01535.18 151698.1_53729120_1 - 6.3e-44 145.1 15.6 3.4e-05 23.7 0.0 10.5 10 0 0 10 10 10 8 PPR repeat PPR_2 PF13041.4 151698.1_53729120_1 - 6.4e-44 147.8 7.4 8.9e-08 32.1 0.0 9.1 7 2 2 9 9 9 8 PPR repeat family PPR_1 PF12854.5 151698.1_53729120_1 - 3.6e-26 90.4 2.2 0.0023 17.5 0.1 7.9 7 0 0 7 7 7 5 PPR repeat PPR_3 PF13812.4 151698.1_53729120_1 - 1.5e-05 24.8 0.0 21 5.1 0.1 6.1 6 1 0 7 7 7 2 Pentatricopeptide repeat domain TPR_14 PF13428.4 151698.1_53729120_1 - 0.038 14.7 1.1 20 6.2 0.4 5.0 6 1 1 7 7 7 0 Tetratricopeptide repeat Ribosomal_L19 PF01245.18 151698.1_53729120_2 - 2.6e-28 98.0 1.2 4e-28 97.4 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Pkinase PF00069.23 001359376.1_53724001_1 - 9.8e-51 172.5 0.0 1.4e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001359376.1_53724001_1 - 2e-19 69.8 0.0 6.4e-19 68.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001359376.1_53724001_1 - 0.0043 16.3 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_38 PF01074.20 001359353.1_53727001_1 - 4.4e-92 308.4 3.4 6.8e-92 307.8 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.11 001359353.1_53727001_1 - 1.4e-74 251.6 0.0 9e-39 133.6 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.9 001359353.1_53727001_1 - 1.4e-17 63.7 0.1 3.9e-17 62.3 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain NUDIX PF00293.26 153104.1_53723120_2 - 1.4e-22 80.0 0.4 2.7e-22 79.1 0.2 1.6 2 0 0 2 2 2 1 NUDIX domain USP7_ICP0_bdg PF12436.6 001359435.1_53729001_3 - 1.8e-77 259.8 0.1 5.8e-76 254.9 0.0 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.4 001359435.1_53729001_3 - 2.3e-59 200.5 12.2 9.1e-58 195.3 2.0 3.5 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.27 001359435.1_53729001_3 - 2.1e-46 158.4 1.7 4.1e-46 157.4 1.7 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 001359435.1_53729001_3 - 3.9e-24 85.7 0.1 8.3e-24 84.6 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.24 001359435.1_53729001_3 - 2.3e-21 75.9 0.2 8e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 MATH domain RA PF00788.21 001359435.1_53729001_3 - 4.1e-05 24.0 0.3 2.7 8.6 0.0 4.0 4 0 0 4 4 4 2 Ras association (RalGDS/AF-6) domain DUF3781 PF12636.5 001359435.1_53729001_3 - 0.12 12.2 1.2 9.8 6.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) zf-DHHC PF01529.18 001359432.1_53726001_2 - 5.8e-30 104.0 9.9 5.8e-30 104.0 9.9 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF629 PF04780.10 001359392.1_53729001_2 - 1.6e-155 518.3 3.3 3.4e-155 517.2 3.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF629) DUF627 PF04781.10 001359392.1_53729001_2 - 3.1e-23 81.7 0.8 6.6e-23 80.7 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF627) UCH PF00443.27 001359392.1_53729001_2 - 4.7e-22 78.6 0.1 1.1e-21 77.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_14 PF13428.4 001359392.1_53729001_2 - 0.8 10.6 18.5 0.27 12.0 0.9 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.15 001359392.1_53729001_2 - 7.2 6.9 8.9 18 5.6 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.4 001359392.1_53729001_2 - 9.1 6.9 12.8 5.7 7.6 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_1 PF00667.18 001359515.1_53726001_1 - 4.2e-71 238.9 0.0 7e-71 238.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.23 001359515.1_53726001_1 - 4.5e-35 120.8 2.0 1.9e-34 118.8 2.0 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.19 001359515.1_53726001_1 - 6.9e-18 65.2 0.1 1.5e-15 57.6 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF2685 PF10886.6 001359515.1_53726001_1 - 0.16 12.1 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) DJ-1_PfpI PF01965.22 001137243.1_53723001_2 - 2.7e-63 212.6 7.4 9.2e-32 110.0 0.3 2.1 2 0 0 2 2 2 2 DJ-1/PfpI family GATase_3 PF07685.12 001137243.1_53723001_2 - 0.051 13.0 0.3 6.2 6.2 0.0 2.1 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Bestrophin PF01062.19 001359599.1_53729001_3 - 0.14 11.3 0.1 0.27 10.4 0.1 1.4 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Methyltransf_16 PF10294.7 001359567.1_53724001_2 - 1.1e-18 67.4 0.1 2.8e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase NB-ARC PF00931.20 001359661.1_53726001_3 - 3.1e-36 124.8 0.0 5.4e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain LRR_4 PF12799.5 001359661.1_53726001_3 - 0.0001 22.5 0.5 0.00022 21.4 0.3 5.3 5 1 3 8 8 8 2 Leucine Rich repeats (2 copies) AAA_16 PF13191.4 001359661.1_53726001_3 - 0.00059 20.1 1.4 0.0019 18.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain LRR_8 PF13855.4 001359661.1_53726001_3 - 0.011 15.3 5.5 0.021 14.5 0.0 3.7 2 2 2 4 4 4 0 Leucine rich repeat NACHT PF05729.10 001359661.1_53726001_3 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RPW8 PF05659.9 001359661.1_53726001_3 - 0.042 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 AAA_14 PF13173.4 001359661.1_53726001_3 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain LIAS_N PF16881.3 001359661.1_53726001_3 - 0.051 13.9 0.2 0.13 12.6 0.2 1.6 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family TIP49 PF06068.11 001359661.1_53726001_3 - 0.3 9.8 0.7 0.66 8.7 0.6 1.5 2 0 0 2 2 2 0 TIP49 C-terminus LRR_1 PF00560.31 001359661.1_53726001_3 - 8.2 7.2 10.9 4.5 8.0 0.2 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat RRM_1 PF00076.20 001359719.1_53723001_3 - 7e-15 54.5 0.0 1.1e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.21 001359719.1_53723001_3 - 1.5e-06 27.8 1.8 1.5e-06 27.8 1.8 2.4 2 0 0 2 2 2 1 Zinc knuckle Proteasome PF00227.24 001359711.1_53723001_3 - 1.1e-46 158.6 0.5 1.4e-46 158.3 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit NblA PF04485.10 001359711.1_53723001_3 - 0.017 15.4 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA PRR18 PF15671.3 001359711.1_53723001_3 - 0.025 14.3 0.9 0.036 13.8 0.9 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 Ribosomal_S10 PF00338.20 001111814.2_53722001_3 - 2.4e-26 91.7 0.2 3.4e-26 91.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Coprogen_oxidas PF01218.16 001195846.1_53723001_1 - 1.3e-133 444.1 0.0 1.6e-133 443.9 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Actin PF00022.17 144502.1_53724120_1 - 1.8e-05 23.5 0.0 2.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Actin Actin PF00022.17 144502.1_53724120_3 - 1.5e-15 56.6 0.0 2.1e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Actin Ribosomal_L27A PF00828.17 001137118.2_53723001_2 - 1e-29 103.5 1.7 1.4e-29 103.1 1.7 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DENN PF02141.19 001360066.1_53726001_2 - 2.1e-28 99.4 1.7 8.4e-25 87.7 0.3 2.7 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.16 001360066.1_53726001_2 - 1.3e-07 32.2 0.1 3.4e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.17 001360066.1_53726001_2 - 0.00031 20.6 0.3 0.00085 19.1 0.3 1.8 1 0 0 1 1 1 1 dDENN domain SPA PF08616.8 001360066.1_53726001_2 - 0.0076 16.1 0.2 0.019 14.8 0.2 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis NAD_binding_10 PF13460.4 001360079.1_53723001_1 - 2.1e-19 70.0 0.0 5.8e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.19 001360079.1_53723001_1 - 7.4e-12 45.1 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001360079.1_53723001_1 - 3.3e-09 36.0 0.0 5.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.11 001360079.1_53723001_1 - 6.5e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.3 001360079.1_53723001_1 - 0.012 14.8 0.0 0.026 13.8 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.15 001360079.1_53723001_1 - 0.037 13.0 0.0 0.086 11.8 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain UVR PF02151.17 153391.1_53722120_1 - 0.0081 15.7 0.3 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 UvrB/uvrC motif TniB PF05621.9 153391.1_53722120_1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Lysis_col PF02402.14 153391.1_53722120_1 - 0.091 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Lysis protein PIG-Y PF15159.4 153400.1_53724120_3 - 2.9e-28 98.3 6.5 4.6e-28 97.7 6.5 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DPM2 PF07297.10 153400.1_53724120_3 - 0.66 10.2 4.3 1.1 9.4 4.3 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PP2C PF00481.19 001360109.1_53724001_3 - 7.8e-39 133.7 0.0 1.4e-37 129.6 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.10 001360109.1_53724001_3 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) zf-RING_2 PF13639.4 153395.1_53725120_3 - 2.4e-09 37.2 9.9 9.3e-09 35.3 9.9 2.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 153395.1_53725120_3 - 4.5e-07 29.9 6.4 1.2e-06 28.6 6.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 153395.1_53725120_3 - 1.3e-05 24.6 0.3 1.3e-05 24.6 0.3 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 153395.1_53725120_3 - 2e-05 24.2 8.3 6.6e-05 22.5 8.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 153395.1_53725120_3 - 0.00032 20.5 2.4 0.00059 19.7 2.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.23 153395.1_53725120_3 - 0.0048 16.6 9.0 0.0048 16.6 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 153395.1_53725120_3 - 0.016 14.9 8.7 0.016 14.9 8.7 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 153395.1_53725120_3 - 0.034 13.9 7.7 0.11 12.2 7.7 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 153395.1_53725120_3 - 0.046 13.6 8.0 0.15 11.9 8.0 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.4 153395.1_53725120_3 - 0.11 12.4 7.0 0.14 12.0 4.9 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.4 153394.1_53723120_2 - 1.2e-09 38.2 9.7 5.2e-09 36.1 9.7 2.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 153394.1_53723120_2 - 9.1e-07 28.9 9.2 2.6e-06 27.5 9.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 153394.1_53723120_2 - 8.3e-06 25.3 0.3 8.3e-06 25.3 0.3 2.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 153394.1_53723120_2 - 1.8e-05 24.4 9.1 7.1e-05 22.4 9.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 153394.1_53723120_2 - 0.00017 21.4 2.6 0.00032 20.6 2.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.23 153394.1_53723120_2 - 0.0029 17.3 9.0 0.0029 17.3 9.0 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 153394.1_53723120_2 - 0.0032 17.2 8.5 0.0032 17.2 8.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 153394.1_53723120_2 - 0.065 13.1 7.3 0.11 12.5 5.2 2.6 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.4 153394.1_53723120_2 - 1.1 9.1 13.4 0.066 12.9 7.7 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ATP-synt_E PF05680.10 001357858.1_53721001_1 - 0.00073 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase E chain EB_dh PF09459.8 001147548.1_53724001_1 - 3.7e-27 95.7 1.1 4.6e-27 95.4 1.1 1.1 1 0 0 1 1 1 1 Ethylbenzene dehydrogenase OMPdecase PF00215.22 153423.1_53725120_3 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family CBS PF00571.26 001360302.1_53725001_2 - 5.4e-25 87.5 12.6 2e-07 31.2 0.1 4.6 4 0 0 4 4 4 4 CBS domain PB1 PF00564.22 001360302.1_53725001_2 - 4.4e-15 55.2 0.3 9.5e-15 54.1 0.3 1.6 1 0 0 1 1 1 1 PB1 domain DUF512 PF04459.10 001360302.1_53725001_2 - 0.064 12.4 0.2 0.16 11.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF512) SEN1_N PF12726.5 001360302.1_53725001_2 - 0.077 11.1 0.0 0.13 10.3 0.0 1.3 1 0 0 1 1 1 0 SEN1 N terminal MIP PF00230.18 001111553.1_53723001_1 - 3.1e-79 265.7 13.1 4e-79 265.4 13.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein zf-C3HC4_5 PF17121.3 001111553.1_53723001_1 - 0.22 11.3 2.5 0.54 10.0 2.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MIP PF00230.18 001111552.1_53723001_3 - 7.1e-84 280.9 12.2 8.8e-84 280.6 12.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein FPP PF05911.9 001360558.1_53729001_2 - 0 1073.1 69.3 0 1073.1 69.3 2.4 2 1 0 2 2 2 1 Filament-like plant protein, long coiled-coil IncA PF04156.12 001360558.1_53729001_2 - 0.0019 17.9 16.8 0.0019 17.9 16.8 6.6 5 2 1 6 6 6 2 IncA protein DUF724 PF05266.12 001360558.1_53729001_2 - 0.0026 17.5 6.8 0.0026 17.5 6.8 6.8 4 2 3 8 8 8 1 Protein of unknown function (DUF724) DUF730 PF05325.9 001360558.1_53729001_2 - 0.0057 16.5 0.1 0.0057 16.5 0.1 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF730) RNA_binding PF01877.15 001360558.1_53729001_2 - 1.1 9.4 16.1 0.5 10.5 0.2 4.1 4 0 0 4 4 4 0 RNA binding RRM_1 PF00076.20 001360652.1_53723001_1 - 1.3e-09 37.6 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAL_effector PF03377.11 001360605.1_53723001_1 - 0.21 11.4 3.4 0.64 9.9 1.2 2.6 2 0 0 2 2 2 0 TAL effector repeat Glycolytic PF00274.17 001360605.1_53723001_2 - 1.3e-164 546.9 0.0 1.5e-164 546.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I zf-C3HC4_3 PF13920.4 001360644.1_53727001_1 - 1.2e-08 34.6 6.6 2.5e-08 33.5 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001360644.1_53727001_1 - 1.9e-07 30.7 9.3 4.6e-07 29.4 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001360644.1_53727001_1 - 6.8e-07 28.9 9.0 1.8e-06 27.6 9.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001360644.1_53727001_1 - 9.1e-06 25.4 9.5 2e-05 24.3 9.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.4 001360644.1_53727001_1 - 0.00038 20.5 8.6 0.00097 19.2 8.6 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.4 001360644.1_53727001_1 - 0.003 17.2 7.2 0.0073 16.0 7.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 001360644.1_53727001_1 - 0.01 15.7 8.2 0.024 14.5 8.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.4 001360644.1_53727001_1 - 0.014 15.1 5.0 0.026 14.2 5.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.5 001360644.1_53727001_1 - 0.42 10.8 5.4 1.2 9.4 5.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.4 001360644.1_53727001_1 - 0.62 9.7 5.6 1.4 8.5 5.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UQ_con PF00179.24 153662.1_53725120_1 - 1.3e-09 37.7 0.0 2.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L11_N PF03946.12 153662.1_53725120_2 - 1.4e-17 63.1 0.0 2.6e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.17 153662.1_53725120_2 - 7.3e-17 61.5 0.3 1.3e-16 60.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ank_3 PF13606.4 153662.1_53725120_3 - 0.013 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Na_Ca_ex PF01699.22 001360697.1_53724001_1 - 2.2e-37 128.2 34.7 1e-18 67.6 17.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2157 PF09925.7 001360697.1_53724001_1 - 2.9 7.5 9.8 0.89 9.2 1.0 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) BET PF17035.3 001360688.1_53723001_2 - 1.4e-19 69.9 0.0 3.5e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.23 001360688.1_53723001_2 - 2.6e-18 65.7 0.1 6.6e-18 64.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain FlaC_arch PF05377.9 001360688.1_53723001_2 - 0.085 13.1 0.1 4.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MFAP1 PF06991.9 001360688.1_53723001_2 - 1.5 8.5 11.0 2.9 7.5 11.0 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing SOG2 PF10428.7 001360700.1_53723001_1 - 0.21 10.7 16.3 0.25 10.4 16.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF538 PF04398.10 001360700.1_53723001_3 - 8.6e-28 96.9 0.0 1.1e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF538 BRX PF08381.9 001360666.1_53724001_3 - 1.5e-54 181.0 11.1 1.4e-27 94.7 2.5 2.3 2 0 0 2 2 2 2 Transcription factor regulating root and shoot growth via Pin3 BRX_N PF13713.4 001360666.1_53724001_3 - 1.5e-15 56.5 0.3 3e-15 55.5 0.3 1.5 1 0 0 1 1 1 1 Transcription factor BRX N-terminal domain Whirly PF08536.9 001288226.1_48623001_3 - 3.1e-62 208.2 0.0 6.8e-62 207.1 0.0 1.6 2 0 0 2 2 2 1 Whirly transcription factor SUIM_assoc PF16619.3 001288226.1_48623001_3 - 0.0021 18.0 4.1 0.0039 17.1 4.1 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CENP-B_dimeris PF09026.8 001321779.1_53722001_2 - 1 9.6 6.9 1.9 8.8 6.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C3HC4 PF00097.23 001358638.1_53725001_1 - 1.2e-06 28.2 9.5 2.8e-06 26.9 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001358638.1_53725001_1 - 1.3e-06 27.9 9.4 2.6e-06 27.0 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001358638.1_53725001_1 - 0.00023 21.0 6.3 0.0005 19.9 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001358638.1_53725001_1 - 0.00045 20.0 9.4 0.00045 20.0 9.4 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.4 001358638.1_53725001_1 - 0.0034 17.5 8.0 0.0034 17.5 8.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.3 001358638.1_53725001_1 - 0.033 14.2 5.6 0.085 12.9 5.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.4 001358638.1_53725001_1 - 0.64 10.1 8.6 1.5 8.9 8.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Golgin_A5 PF09787.7 001358638.1_53725001_1 - 0.95 8.7 25.9 1.5 8.1 25.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-RING_6 PF14835.4 001358638.1_53725001_1 - 2.5 7.9 8.9 5.7 6.8 8.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF2690 PF10901.6 001138845.1_53722001_2 - 0.014 15.6 0.3 0.022 14.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) MORN PF02493.18 001360760.1_53722001_3 - 2.4e-10 39.5 15.5 1.2e-05 24.8 0.3 3.5 4 0 0 4 4 4 2 MORN repeat DUF572 PF04502.11 001136676.1_53724001_3 - 8.5e-59 199.6 0.1 1.2e-58 199.1 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) PEPCK_ATP PF01293.18 001309908.1_53726001_2 - 1.1e-213 710.0 0.0 1.3e-213 709.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.4 001309908.1_53726001_2 - 0.014 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.4 001309908.1_53726001_2 - 0.094 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol PF00940.17 001348524.1_53728001_1 - 4.1e-154 513.2 0.0 7.3e-154 512.4 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.4 001348524.1_53728001_1 - 4.9e-74 249.6 0.9 7.3e-74 249.0 0.9 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DIOX_N PF14226.4 001137790.1_53724001_2 - 6.1e-34 117.2 0.0 1.2e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.18 001137790.1_53724001_2 - 1.4e-21 76.7 0.0 2.7e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HMA PF00403.24 153802.1_53724120_3 - 1.2e-09 38.3 0.9 2.1e-09 37.6 0.9 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain SPX PF03105.17 153802.1_53724120_3 - 1.5 8.5 7.9 2 8.1 7.9 1.2 1 0 0 1 1 1 0 SPX domain 2OG-FeII_Oxy_2 PF13532.4 153803.1_53724120_1 - 2.3e-11 44.2 0.3 8.7e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily PPR PF01535.18 153804.1_53729120_1 - 0.0028 17.6 1.6 0.66 10.2 0.3 2.6 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.4 153804.1_53729120_1 - 0.011 15.8 0.7 0.84 9.8 0.1 2.5 3 0 0 3 3 3 0 PPR repeat family RecA PF00154.19 153804.1_53729120_3 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein RecA PF00154.19 153805.1_53724120_3 - 0.00097 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AUX_IAA PF02309.14 001358397.1_53723001_1 - 8.3e-67 225.4 0.4 3.3e-66 223.5 0.4 2.0 1 1 0 1 1 1 1 AUX/IAA family PAP_assoc PF03828.17 001148132.2_53724001_1 - 6.8e-05 22.9 0.8 0.00031 20.7 0.8 2.0 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.21 001148132.2_53724001_2 - 7.3e-05 22.9 0.2 0.00012 22.2 0.2 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Vac_ImportDeg PF09783.7 001148065.3_53724001_1 - 3e-48 163.6 0.0 4.1e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF5134 PF17197.2 153816.1_53722120_3 - 0.063 13.1 0.4 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) Zein PF01559.14 153438.1_53722120_3 - 2.1e-58 197.6 62.2 8.9e-56 189.0 62.2 2.1 1 1 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 152429.1_53723120_3 - 1.2e-45 155.7 59.7 8.3e-16 58.1 24.7 3.4 2 1 1 3 3 3 3 Zein seed storage protein Zein PF01559.14 153775.1_53722120_2 - 4.7e-46 157.1 68.3 3.8e-36 124.7 44.9 2.0 1 1 1 2 2 2 2 Zein seed storage protein DUF4800 PF16057.3 153775.1_53722120_2 - 0.19 10.9 3.0 0.24 10.5 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Zein PF01559.14 153775.1_53722120_3 - 1.4e-18 67.1 12.9 2e-18 66.6 12.9 1.2 1 0 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 153774.1_53722120_2 - 4.7e-48 163.7 54.8 2.8e-30 105.4 23.8 2.0 1 1 1 2 2 2 2 Zein seed storage protein Zein PF01559.14 153774.1_53722120_3 - 7.2e-06 25.5 1.1 1e-05 25.0 1.1 1.2 1 0 0 1 1 1 1 Zein seed storage protein DUF1010 PF06231.9 153774.1_53722120_3 - 1.6 9.1 8.0 0.13 12.7 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1010) EamA PF00892.18 001165703.1_53723001_1 - 1.5e-23 83.3 35.5 3.1e-14 53.2 15.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family TMEM72 PF16054.3 001165703.1_53723001_1 - 0.045 13.3 0.0 0.045 13.3 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein family 72 Halogen_Hydrol PF10112.7 001165703.1_53723001_1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Fox-1_C PF12414.6 001157017.1_53722001_1 - 0.098 12.9 0.6 0.17 12.1 0.6 1.3 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal AGP PF06376.10 001157017.1_53722001_3 - 1.6e-15 56.5 1.4 1.6e-15 56.5 1.4 2.2 2 1 0 2 2 2 1 Arabinogalactan peptide DUF4220 PF13968.4 001157017.1_53722001_3 - 0.11 12.0 0.5 0.14 11.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CN_hydrolase PF00795.20 001358073.1_53724001_1 - 5.6e-58 196.2 0.0 1.1e-56 191.9 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase zf-RING_2 PF13639.4 001156471.1_53723001_1 - 3.6e-13 49.4 5.9 3.6e-13 49.4 5.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.4 001156471.1_53723001_1 - 3.5e-10 39.4 5.9 3.5e-10 39.4 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.4 001156471.1_53723001_1 - 4.9e-10 39.4 2.3 4.9e-10 39.4 2.3 2.9 3 0 0 3 3 3 1 zinc-ribbon zf-RING_11 PF17123.3 001156471.1_53723001_1 - 1.5e-08 34.1 0.5 5e-08 32.4 0.5 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.23 001156471.1_53723001_1 - 1.4e-07 31.1 12.6 2.1e-07 30.6 3.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001156471.1_53723001_1 - 7.8e-06 25.7 1.5 2.1e-05 24.4 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.4 001156471.1_53723001_1 - 2.3e-05 24.0 10.7 0.00013 21.6 3.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001156471.1_53723001_1 - 2.4e-05 24.1 0.6 2.4e-05 24.1 0.6 2.0 2 1 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.5 001156471.1_53723001_1 - 5.8e-05 23.2 11.3 5.8e-05 23.2 11.3 2.3 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.4 001156471.1_53723001_1 - 0.00047 19.9 3.5 0.00047 19.9 3.5 2.8 2 1 1 3 3 3 1 zinc-RING finger domain Rad50_zn_hook PF04423.12 001156471.1_53723001_1 - 0.0086 15.8 5.1 0.2 11.4 0.1 3.3 3 0 0 3 3 3 1 Rad50 zinc hook motif Prok-RING_4 PF14447.4 001156471.1_53723001_1 - 0.38 10.5 16.4 0.55 10.0 10.3 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DZR PF12773.5 001156471.1_53723001_1 - 0.42 10.5 7.1 2.5 8.1 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-C2HC5 PF06221.11 001156471.1_53723001_1 - 0.5 10.3 5.3 1.3 9.0 0.2 2.7 3 0 0 3 3 2 0 Putative zinc finger motif, C2HC5-type Prok-RING_1 PF14446.4 001156471.1_53723001_1 - 2.8 7.8 9.8 14 5.5 0.3 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.4 001156471.1_53723001_1 - 3.5 7.3 11.8 1.4 8.5 3.8 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.10 001156471.1_53723001_1 - 4.6 7.5 11.2 12 6.1 0.2 3.5 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-RING-like PF08746.9 001156471.1_53723001_1 - 6.1 7.1 11.7 0.074 13.2 2.9 2.3 2 1 0 2 2 2 0 RING-like domain OrfB_Zn_ribbon PF07282.9 001156471.1_53723001_1 - 7.2 6.5 6.2 4 7.3 0.3 2.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Metallophos PF00149.26 001157706.2_53723001_3 - 1.3e-17 64.9 0.0 1.8e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.5 001157706.2_53723001_3 - 0.0001 22.4 0.1 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.8 001157706.2_53723001_3 - 0.028 13.3 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoD-like phosphatase HLH PF00010.24 001357701.1_53724001_1 - 6.3e-10 38.7 0.4 1.1e-09 37.9 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Holin_BhlA PF10960.6 001357701.1_53724001_1 - 2.6 7.9 4.0 0.56 10.1 0.6 1.6 2 0 0 2 2 2 0 BhlA holin family Mito_carr PF00153.25 001153006.1_53724001_3 - 4.9e-75 247.4 0.9 3.2e-24 84.5 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein VWA_2 PF13519.4 001154383.3_53726001_3 - 1.4e-13 51.3 0.9 3e-13 50.2 0.3 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.26 001154383.3_53726001_3 - 6.5e-10 39.4 0.0 1.1e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_11 PF17123.3 001154383.3_53726001_3 - 6.6e-07 28.8 1.7 1.8e-06 27.4 1.7 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.4 001154383.3_53726001_3 - 3.8e-06 26.9 2.2 8.3e-06 25.8 2.2 1.6 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.4 001154383.3_53726001_3 - 2.6e-05 24.0 0.6 6.6e-05 22.7 0.6 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4 PF00097.23 001154383.3_53726001_3 - 0.00018 21.2 1.8 0.00038 20.1 1.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001154383.3_53726001_3 - 0.00024 21.2 2.0 0.00057 20.0 2.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.4 001154383.3_53726001_3 - 0.0036 17.0 1.9 0.0079 15.9 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.27 001154383.3_53726001_3 - 0.0039 16.9 0.7 0.008 15.9 0.7 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.4 001154383.3_53726001_3 - 0.0092 15.8 2.6 0.018 14.8 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 001154383.3_53726001_3 - 0.015 15.2 2.1 0.036 14.0 2.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.4 001154383.3_53726001_3 - 0.018 14.9 0.6 0.046 13.6 0.2 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001154383.3_53726001_3 - 0.098 12.7 1.4 0.23 11.5 1.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING adh_short_C2 PF13561.4 001155041.1_53723001_3 - 8.2e-63 212.0 5.6 1.2e-62 211.5 5.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001155041.1_53723001_3 - 4.3e-55 186.1 2.1 6.4e-55 185.5 2.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001155041.1_53723001_3 - 2.8e-12 46.8 2.7 4.7e-12 46.1 2.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001155041.1_53723001_3 - 3.6e-07 29.8 1.6 2.1e-06 27.3 1.6 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001155041.1_53723001_3 - 0.0002 20.3 0.8 0.00034 19.5 0.8 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.19 001147342.1_53723001_2 - 1.5e-31 109.6 0.0 2.2e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001147342.1_53723001_2 - 3.1e-20 72.2 0.0 4.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001147342.1_53723001_2 - 9.2e-19 67.9 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001147342.1_53723001_2 - 2.2e-18 66.2 0.0 2e-14 53.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.3 001147342.1_53723001_2 - 4.6e-17 62.3 0.0 1.6e-16 60.5 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.11 001147342.1_53723001_2 - 1e-10 41.4 0.1 1.5e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.13 001147342.1_53723001_2 - 4.2e-07 29.3 0.2 2.7e-06 26.6 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001147342.1_53723001_2 - 3.3e-06 26.3 0.0 4.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.23 001147342.1_53723001_2 - 0.064 12.6 0.2 0.29 10.4 0.1 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.22 001147342.1_53723001_2 - 0.09 13.1 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Amino_oxidase PF01593.22 001323613.1_53725001_2 - 1.7e-91 307.7 0.0 2e-91 307.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001323613.1_53725001_2 - 5.1e-14 52.1 0.2 1.2e-13 51.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.22 001323613.1_53725001_2 - 6.3e-10 38.6 0.7 2e-06 27.0 0.1 3.0 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.12 001323613.1_53725001_2 - 1.5e-06 27.5 1.8 0.00065 18.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.12 001323613.1_53725001_2 - 2.9e-05 22.8 1.7 0.0014 17.3 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.25 001323613.1_53725001_2 - 3.2e-05 24.3 1.6 0.0025 18.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001323613.1_53725001_2 - 3.9e-05 22.8 1.0 0.0051 15.8 0.0 2.4 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_oxidored PF12831.5 001323613.1_53725001_2 - 0.00066 19.0 0.7 0.00088 18.6 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.22 001323613.1_53725001_2 - 0.001 18.7 4.8 0.012 15.1 4.8 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.4 001323613.1_53725001_2 - 0.0017 17.5 0.4 0.16 11.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.4 001323613.1_53725001_2 - 0.0033 17.3 1.4 1.3 8.8 0.1 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.15 001323613.1_53725001_2 - 0.031 13.4 0.0 0.075 12.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.17 001323613.1_53725001_2 - 0.11 11.7 0.1 0.21 10.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.19 001323613.1_53725001_2 - 0.14 11.3 0.0 0.3 10.2 0.0 1.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.10 001323613.1_53725001_2 - 0.14 11.0 0.5 0.73 8.7 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein OTU PF02338.17 001291850.1_53725001_2 - 1.5e-15 57.7 0.1 2.8e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.7 001291850.1_53725001_2 - 4.9e-07 29.3 0.5 0.0024 17.2 0.1 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain UBA PF00627.29 001291850.1_53725001_2 - 0.066 13.0 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 UBA/TS-N domain DLD PF14878.4 001291850.1_53725001_2 - 0.069 13.6 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Death-like domain of SPT6 4HBT_2 PF13279.4 001326549.1_53722001_2 - 2.3e-10 40.9 0.0 3.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.20 001326549.1_53722001_2 - 2.6e-10 40.4 0.0 4.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.15 001326549.1_53722001_2 - 0.004 16.4 0.0 0.086 12.0 0.0 2.0 1 1 1 2 2 2 1 Acyl-ACP thioesterase DUF2321 PF10083.7 001326549.1_53722001_3 - 0.055 13.0 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF260 PF03195.12 001138342.1_53723001_2 - 1.8e-11 44.1 0.7 4.4e-11 42.9 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF260 DUF260 PF03195.12 001138342.1_53723001_3 - 1e-05 25.7 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF260 IATP PF04568.10 001328070.1_53722001_2 - 7e-06 26.3 0.7 1.3e-05 25.3 0.7 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Glycos_transf_4 PF00953.19 001147236.1_53724001_1 - 2.8e-18 66.3 10.3 5.5e-18 65.3 10.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 4 Pkinase_Tyr PF07714.15 001359734.1_53725001_3 - 3.3e-52 177.2 0.0 4.4e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001359734.1_53725001_3 - 3e-47 161.1 0.0 4.2e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain S_locus_glycop PF00954.18 001359734.1_53725001_3 - 2.7e-16 59.9 0.3 2.7e-16 59.9 0.3 1.8 2 0 0 2 2 2 1 S-locus glycoprotein domain PAN_2 PF08276.9 001359734.1_53725001_3 - 1.3e-14 53.8 4.9 2.8e-14 52.8 4.9 1.6 1 0 0 1 1 1 1 PAN-like domain DUF3403 PF11883.6 001359734.1_53725001_3 - 1.8e-08 34.3 0.0 5e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3403) B_lectin PF01453.22 001359734.1_53725001_3 - 2.7e-07 30.5 1.0 8.3e-07 28.9 0.3 2.2 2 0 0 2 2 2 1 D-mannose binding lectin APH PF01636.21 001359734.1_53725001_3 - 0.0058 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EGF_2 PF07974.11 001359734.1_53725001_3 - 0.61 10.4 14.5 0.075 13.3 4.5 3.1 2 0 0 2 2 2 0 EGF-like domain Chorion_3 PF05387.9 001138330.1_53723001_1 - 7.3 6.0 8.1 13 5.2 8.1 1.3 1 0 0 1 1 1 0 Chorion family 3 Pkinase_Tyr PF07714.15 001357931.1_53725001_2 - 1.2e-44 152.4 0.0 1.7e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001357931.1_53725001_2 - 1.5e-44 152.3 0.0 2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WAK_assoc PF14380.4 001357931.1_53725001_2 - 5.3e-18 65.5 0.0 1.5e-17 64.0 0.0 1.9 1 1 1 2 2 2 1 Wall-associated receptor kinase C-terminal TMEM51 PF15345.4 001357931.1_53725001_2 - 0.00061 19.6 0.0 0.0014 18.4 0.0 1.6 2 0 0 2 2 2 1 Transmembrane protein 51 APH PF01636.21 001357931.1_53725001_2 - 0.0092 15.8 0.4 0.13 12.0 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.13 001357931.1_53725001_2 - 0.056 13.1 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ABC1 PF03109.14 001357931.1_53725001_2 - 0.091 12.8 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC1 family SKG6 PF08693.8 001357931.1_53725001_2 - 0.31 10.4 2.9 0.68 9.3 2.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pinin_SDK_memA PF04696.11 001137213.1_53724001_1 - 5e-17 62.0 19.3 5e-17 62.0 19.3 2.1 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Pinin_SDK_memA PF04696.11 001137213.1_53724001_2 - 0.015 15.2 0.5 0.015 15.2 0.5 2.3 1 1 1 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF1977 PF09320.9 001137213.1_53724001_2 - 0.082 13.0 2.1 0.18 12.0 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) TauE PF01925.17 001360947.1_53725001_2 - 1.1e-22 80.7 38.9 8.8e-13 48.3 16.3 2.5 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE Arm PF00514.21 001152237.2_53726001_2 - 3.5e-39 131.5 21.0 2.8e-09 36.6 0.0 9.5 10 1 0 10 10 10 7 Armadillo/beta-catenin-like repeat BTB PF00651.29 001152237.2_53726001_2 - 1.3e-25 89.6 0.0 3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain HEAT PF02985.20 001152237.2_53726001_2 - 1.2e-08 34.3 6.4 0.1 12.7 0.0 6.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.4 001152237.2_53726001_2 - 7.3e-07 29.3 18.7 0.004 17.4 0.2 6.9 4 1 3 7 7 7 3 HEAT repeats Atx10homo_assoc PF09759.7 001152237.2_53726001_2 - 2.1e-06 27.6 0.2 0.0075 16.2 0.1 2.9 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.4 001152237.2_53726001_2 - 2.2e-05 24.7 16.5 0.074 13.4 0.1 6.7 7 0 0 7 7 7 2 HEAT-like repeat V-ATPase_H_N PF03224.12 001152237.2_53726001_2 - 4.3e-05 22.8 3.5 0.059 12.5 0.2 3.5 1 1 2 3 3 3 2 V-ATPase subunit H DUF3361 PF11841.6 001152237.2_53726001_2 - 0.00012 21.9 1.5 0.28 11.0 0.2 4.1 4 1 1 5 5 5 2 Domain of unknown function (DUF3361) Adaptin_N PF01602.18 001152237.2_53726001_2 - 0.00025 19.6 0.4 0.023 13.1 0.1 2.9 1 1 0 1 1 1 1 Adaptin N terminal region IFRD PF05004.11 001152237.2_53726001_2 - 0.00069 18.7 1.5 0.099 11.6 0.1 2.8 1 1 1 2 2 2 2 Interferon-related developmental regulator (IFRD) RST PF12174.6 153842.1_53725120_2 - 1.2e-05 25.1 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain Zein PF01559.14 153840.1_53721120_1 - 7.2e-18 64.8 12.2 8.3e-18 64.6 12.2 1.0 1 0 0 1 1 1 1 Zein seed storage protein Mg_trans_NIPA PF05653.12 001152371.1_53723001_1 - 1.2e-06 27.8 3.1 1.7e-06 27.3 3.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.18 001152371.1_53723001_1 - 7.9e-05 22.7 2.7 0.00016 21.8 2.7 1.5 1 0 0 1 1 1 1 EamA-like transporter family Multi_Drug_Res PF00893.17 001152371.1_53723001_1 - 0.0018 18.8 0.9 0.004 17.6 0.9 1.6 1 0 0 1 1 1 1 Small Multidrug Resistance protein TMEM234 PF10639.7 001152371.1_53723001_1 - 0.0052 16.7 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Putative transmembrane family 234 7TMR-DISM_7TM PF07695.9 001152371.1_53723001_2 - 0.0016 18.3 3.0 0.0026 17.6 3.0 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling Rab5ip PF07019.10 001152371.1_53723001_2 - 0.22 12.0 2.0 0.71 10.4 0.1 2.3 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) EamA PF00892.18 001152371.1_53723001_2 - 0.45 10.5 5.6 1.3 9.1 5.5 1.8 1 1 0 1 1 1 0 EamA-like transporter family BaxI_1 PF12811.5 001152371.1_53723001_2 - 0.62 9.5 4.7 0.88 9.0 4.7 1.1 1 0 0 1 1 1 0 Bax inhibitor 1 like Glycos_transf_1 PF00534.18 001360960.1_53724001_2 - 4.3e-39 133.7 0.0 6.5e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001360960.1_53724001_2 - 3.1e-18 66.4 0.0 4.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001360960.1_53724001_2 - 5.4e-14 52.4 1.2 2.3e-13 50.4 0.7 2.2 2 1 1 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.4 001360960.1_53724001_2 - 1.2e-09 38.7 0.2 2.6e-09 37.6 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.4 001360960.1_53724001_2 - 8.7e-05 22.7 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ANAPC5 PF12862.5 001360946.1_53727001_3 - 1.5e-27 95.4 0.9 7.3e-27 93.1 0.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_1 PF00515.26 001360946.1_53727001_3 - 0.00039 20.0 2.9 0.53 10.1 1.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.15 001360946.1_53727001_3 - 0.012 15.5 5.5 0.082 12.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.4 001360946.1_53727001_3 - 0.027 14.5 3.1 0.17 12.0 1.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.4 001360946.1_53727001_3 - 0.049 14.3 4.9 69 4.5 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.4 001360946.1_53727001_3 - 0.085 13.0 7.8 1.7 8.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.4 001360946.1_53727001_3 - 1.9 9.1 11.5 1.1 9.9 1.9 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat bZIP_1 PF00170.19 001360971.1_53723001_1 - 5.1e-11 42.4 12.4 2.4e-10 40.2 12.5 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001360971.1_53723001_1 - 2.1e-09 37.2 13.4 4.6e-09 36.1 13.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001360971.1_53723001_1 - 0.062 13.7 7.4 0.12 12.8 7.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.12 001360971.1_53723001_1 - 0.19 11.4 3.3 0.3 10.7 3.3 1.2 1 0 0 1 1 1 0 IncA protein HAUS6_N PF14661.4 001360971.1_53723001_1 - 0.39 10.2 4.5 0.58 9.6 4.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4033 PF13225.4 001360997.1_53722001_3 - 8e-35 118.6 0.8 1.7e-34 117.5 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) Zein PF01559.14 001112275.2_53722001_3 - 1.6e-84 283.1 78.5 2e-38 132.2 18.1 3.0 1 1 2 3 3 3 3 Zein seed storage protein Methyltrans_RNA PF04452.12 001360990.1_53723001_2 - 2.3e-49 167.6 0.0 2.7e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase Zein PF01559.14 153780.1_53721120_1 - 1.3e-06 28.0 0.6 1.7e-06 27.6 0.6 1.1 1 0 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 152175.1_53722120_2 - 3.2e-87 291.9 65.3 4e-87 291.6 65.3 1.1 1 0 0 1 1 1 1 Zein seed storage protein Zds_C PF08632.8 152175.1_53722120_2 - 0.032 13.9 3.3 0.4 10.3 0.1 3.0 2 1 1 3 3 3 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zein PF01559.14 153776.1_53722120_3 - 5.7e-51 173.2 56.2 1e-47 162.6 56.2 2.0 1 1 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 152427.1_53723120_3 - 8.6e-60 202.1 52.6 2.5e-35 122.0 27.6 2.1 2 0 0 2 2 2 2 Zein seed storage protein RVT_2 PF07727.12 152427.1_53723120_3 - 0.11 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Zein PF01559.14 153777.1_53722120_1 - 5.5e-62 209.3 56.8 1.8e-35 122.4 30.6 2.1 1 1 1 2 2 2 2 Zein seed storage protein DRY_EERY PF09750.7 001361010.1_53724001_3 - 2.6e-36 124.7 0.2 2.6e-36 124.7 0.2 3.4 3 0 0 3 3 3 2 Alternative splicing regulator DNA_pol_phi PF04931.11 001361010.1_53724001_3 - 1.1 7.2 9.9 2 6.3 9.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.8 001361010.1_53724001_3 - 6.7 7.0 13.0 19 5.6 13.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_transf_8 PF01501.18 001361013.1_53726001_3 - 1.4e-44 152.5 0.7 2.1e-44 151.9 0.7 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 TFR_dimer PF04253.13 001361036.1_53726001_2 - 6.1e-27 94.0 0.3 1.2e-26 93.0 0.3 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.15 001361036.1_53726001_2 - 1.7e-22 80.0 0.0 3.1e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.20 001361036.1_53726001_2 - 5.8e-10 39.0 0.1 1.7e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.26 001361036.1_53726001_2 - 0.002 17.7 0.0 0.013 15.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF92 PF01940.14 001361019.1_53723001_3 - 1.6e-73 246.9 10.2 1.9e-73 246.6 10.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 UAA PF08449.9 153854.1_53723120_2 - 2.2e-56 191.2 7.0 2.8e-56 190.8 7.0 1.1 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.8 153854.1_53723120_2 - 0.0012 17.7 5.0 0.0017 17.3 5.0 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.18 153854.1_53723120_2 - 0.0023 18.0 3.5 0.017 15.2 2.3 2.6 3 0 0 3 3 3 1 EamA-like transporter family Peptidase_S8 PF00082.20 153860.1_53723120_1 - 6.5e-19 68.2 0.4 8e-19 67.9 0.4 1.1 1 0 0 1 1 1 1 Subtilase family DSPc PF00782.18 153856.1_53729120_1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RVT_2 PF07727.12 153856.1_53729120_1 - 0.005 16.1 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4629 PF15442.4 153856.1_53729120_2 - 0.059 13.5 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) RVT_2 PF07727.12 153856.1_53729120_3 - 1.7e-54 184.7 0.0 2.5e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DSPc PF00782.18 153856.1_53729120_3 - 3.2e-26 91.6 0.0 5.1e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 153856.1_53729120_3 - 0.002 17.6 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3051 PF11252.6 153856.1_53729120_3 - 0.09 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) Gelsolin PF00626.20 153856.1_53729120_3 - 0.16 11.7 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Gelsolin repeat UAA PF08449.9 153855.1_53723120_2 - 2.7e-61 207.3 13.2 1.4e-51 175.4 7.9 2.1 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.18 153855.1_53723120_2 - 2.6e-05 24.3 13.2 0.00027 21.0 9.1 3.3 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.14 153855.1_53723120_2 - 3e-05 23.4 1.7 3e-05 23.4 1.7 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family PPR_2 PF13041.4 001360939.1_53727001_3 - 1.5e-44 149.8 2.0 1.4e-10 41.1 0.0 7.4 4 1 3 7 7 7 5 PPR repeat family PPR PF01535.18 001360939.1_53727001_3 - 1.5e-34 115.7 4.8 3.5e-07 29.9 0.0 8.1 8 0 0 8 8 8 6 PPR repeat PPR_3 PF13812.4 001360939.1_53727001_3 - 2.6e-30 104.1 0.0 6.1e-08 32.5 0.0 6.0 4 2 2 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.5 001360939.1_53727001_3 - 8.8e-29 98.8 0.0 7.9e-08 31.7 0.0 6.9 7 0 0 7 7 7 5 PPR repeat PPR_long PF17177.2 001360939.1_53727001_3 - 1.1e-14 54.2 0.5 6.5e-07 28.8 0.3 3.3 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001360939.1_53727001_3 - 0.0012 19.4 2.3 28 5.8 0.0 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat ThylakoidFormat PF11264.6 001288409.1_48623001_1 - 4.8e-76 255.1 1.3 7.2e-76 254.5 1.3 1.3 1 0 0 1 1 1 1 Thylakoid formation protein Pollen_Ole_e_I PF01190.15 001111648.1_53724001_3 - 3e-08 33.8 0.1 5e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Pollen proteins Ole e I like Macoilin PF09726.7 001361153.1_53722001_1 - 0.14 10.6 22.0 0.17 10.3 22.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Ndc1_Nup PF09531.8 001361153.1_53722001_1 - 0.44 9.0 9.7 0.5 8.8 9.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cwf_Cwc_15 PF04889.10 001361153.1_53722001_1 - 0.59 9.7 32.0 0.83 9.2 32.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mem_trans PF03547.16 001361153.1_53722001_1 - 2.3 6.4 3.5 2.6 6.2 3.5 1.1 1 0 0 1 1 1 0 Membrane transport protein SRP-alpha_N PF04086.11 001361153.1_53722001_1 - 2.9 7.6 28.3 3.8 7.2 28.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.15 001361153.1_53722001_1 - 3.6 6.1 21.7 5.5 5.5 21.7 1.3 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.7 001361153.1_53722001_1 - 8.8 4.9 26.6 13 4.3 26.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase_Tyr PF07714.15 001361148.1_53725001_2 - 1.2e-45 155.7 0.0 5.6e-45 153.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001361148.1_53725001_2 - 4.6e-44 150.6 0.0 6.3e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Adeno_E3_CR2 PF02439.13 001361148.1_53725001_2 - 0.013 15.1 3.5 0.022 14.4 3.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LysM PF01476.18 001361148.1_53725001_2 - 0.032 14.2 0.0 14 5.8 0.0 3.2 3 0 0 3 3 3 0 LysM domain PspB PF06667.10 001361148.1_53725001_2 - 0.071 13.0 0.2 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Phage shock protein B Zein PF01559.14 001358014.1_53722001_3 - 6.4e-110 366.3 76.8 7.5e-110 366.0 76.8 1.0 1 0 0 1 1 1 1 Zein seed storage protein DDE_Tnp_IS66_C PF13817.4 001358014.1_53722001_3 - 0.25 11.5 2.8 52 4.0 0.1 4.0 3 1 0 3 3 3 0 IS66 C-terminal element Zein PF01559.14 152428.1_53722120_1 - 4.6e-14 52.4 3.5 8.5e-14 51.5 3.5 1.4 1 0 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 152428.1_53722120_3 - 9.8e-26 90.6 19.3 1.6e-25 89.9 19.3 1.3 1 0 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 152430.1_53723120_3 - 8.8e-90 300.3 68.3 1.1e-89 300.0 68.3 1.1 1 0 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 152177.1_53722120_2 - 3.9e-97 324.4 71.4 4.6e-97 324.2 71.4 1.1 1 0 0 1 1 1 1 Zein seed storage protein DDE_Tnp_IS66_C PF13817.4 152177.1_53722120_2 - 0.23 11.5 2.9 36 4.5 0.0 3.8 3 1 0 3 3 3 0 IS66 C-terminal element Zds_C PF08632.8 152177.1_53722120_2 - 8.1 6.2 11.5 0.52 10.0 0.2 3.4 4 0 0 4 4 4 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zein PF01559.14 152180.1_53722120_3 - 1.4e-97 325.9 73.2 1.6e-97 325.6 73.2 1.1 1 0 0 1 1 1 1 Zein seed storage protein TAF8_C PF10406.7 154554.1_53724120_1 - 9.5e-17 61.2 0.2 9.5e-17 61.2 0.2 2.5 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.11 154554.1_53724120_1 - 1.1e-15 57.2 0.1 1.9e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated Caldesmon PF02029.13 154554.1_53724120_1 - 0.034 12.8 0.1 0.05 12.2 0.1 1.1 1 0 0 1 1 1 0 Caldesmon Zein PF01559.14 152431.1_53722120_2 - 8.9e-101 336.3 70.0 1e-100 336.1 70.0 1.0 1 0 0 1 1 1 1 Zein seed storage protein Zds_C PF08632.8 152431.1_53722120_2 - 0.096 12.3 4.9 0.43 10.2 0.4 3.0 2 1 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zein PF01559.14 152426.1_53722120_1 - 1.6e-05 24.4 15.3 3.5e-05 23.3 15.3 1.5 1 1 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 152426.1_53722120_2 - 1.9e-16 60.2 10.0 2.7e-16 59.7 10.0 1.1 1 0 0 1 1 1 1 Zein seed storage protein Zein PF01559.14 152425.1_53722120_3 - 3.3e-101 337.7 73.0 3.9e-101 337.5 73.0 1.0 1 0 0 1 1 1 1 Zein seed storage protein Zds_C PF08632.8 152425.1_53722120_3 - 0.13 11.9 5.2 0.43 10.2 0.4 3.0 2 1 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term TBP PF00352.19 001288161.1_48623001_3 - 2.6e-67 222.6 0.2 2.7e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.6 001288161.1_48623001_3 - 0.0001 22.2 0.1 0.51 10.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) IMS_C PF11799.6 001143044.1_53724001_3 - 1.9e-17 63.9 0.0 3.9e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.4 001143044.1_53724001_3 - 0.055 13.6 2.6 6 7.1 0.7 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4414) zf-FLZ PF04570.12 001150855.1_53723001_2 - 1.9e-20 72.0 0.5 3.3e-20 71.2 0.5 1.4 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 SelP_N PF04592.12 001149182.1_53722001_2 - 1.9 7.7 12.0 2.8 7.1 12.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Aldose_epim PF01263.18 001153842.1_53723001_3 - 9.3e-60 202.3 0.0 1.1e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Y_phosphatase2 PF03162.11 001147046.1_53722001_1 - 2.8e-21 75.7 0.0 3.6e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.11 001147046.1_53722001_3 - 3.7e-32 111.0 0.0 4.7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.4 001147046.1_53722001_3 - 1.2e-07 31.8 0.0 1.6e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.18 001147046.1_53722001_3 - 0.00063 19.4 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001147046.1_53722001_3 - 0.0032 16.9 0.0 0.0038 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF442 PF04273.11 001147046.1_53722001_3 - 0.029 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) AP2 PF00847.18 001153884.1_53723001_3 - 1.1e-13 51.1 2.0 1.8e-13 50.4 2.0 1.4 1 0 0 1 1 1 1 AP2 domain Ribosomal_L14 PF00238.17 001159237.1_53722001_3 - 7.9e-19 67.8 0.0 1.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SMP PF04927.10 001153801.1_53722001_3 - 3.4e-26 91.4 44.0 1.9e-15 57.0 14.1 2.7 3 0 0 3 3 3 2 Seed maturation protein PPR_2 PF13041.4 001154590.1_53725001_3 - 2.6e-55 184.3 14.5 3.3e-15 55.9 1.0 10.1 2 2 8 10 10 10 10 PPR repeat family PPR_1 PF12854.5 001154590.1_53725001_3 - 3.1e-40 135.4 8.1 2.5e-07 30.1 0.0 9.0 9 0 0 9 9 9 7 PPR repeat PPR PF01535.18 001154590.1_53725001_3 - 3.1e-39 130.4 21.1 1.4e-06 28.0 0.0 10.3 10 0 0 10 10 10 8 PPR repeat PPR_3 PF13812.4 001154590.1_53725001_3 - 1.3e-24 85.9 8.7 1.1e-09 38.1 0.4 7.0 4 2 4 9 9 9 5 Pentatricopeptide repeat domain PPR_long PF17177.2 001154590.1_53725001_3 - 7.4e-12 45.0 0.1 8.3e-07 28.4 0.1 3.0 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PROPR TPR_1 PF00515.26 001154590.1_53725001_3 - 0.037 13.7 0.1 1.4 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.4 001154590.1_53725001_3 - 0.075 13.4 0.0 9.5 6.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ZnuA PF01297.15 001154590.1_53725001_3 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Response_reg PF00072.22 001111386.1_53724001_3 - 3.1e-19 69.0 0.0 5.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain BTB PF00651.29 001153383.1_53723001_3 - 1.5e-24 86.2 2.0 1.3e-22 80.0 0.1 2.2 1 1 1 2 2 2 2 BTB/POZ domain LTP_2 PF14368.4 001155486.1_53722001_3 - 3e-15 56.0 6.2 5.9e-15 55.0 6.2 1.5 1 0 0 1 1 1 1 Probable lipid transfer Tryp_alpha_amyl PF00234.20 001155486.1_53722001_3 - 5e-08 33.1 4.1 1e-07 32.2 4.1 1.5 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family 2OG-FeII_Oxy_3 PF13640.4 001254938.1_53723001_1 - 6e-08 33.3 0.0 1.1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.18 001254938.1_53723001_1 - 2.9e-05 24.3 0.0 4.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.4 001254938.1_53723001_3 - 5.1e-06 27.2 0.1 8.9e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily X8 PF07983.11 001154928.1_53723001_2 - 1.6e-19 70.2 10.9 1.6e-19 70.2 10.9 1.7 2 0 0 2 2 2 1 X8 domain AP2 PF00847.18 001154047.1_53723001_1 - 8.4e-12 45.0 3.7 1.5e-11 44.3 3.7 1.4 1 0 0 1 1 1 1 AP2 domain Thioredoxin PF00085.18 001154559.1_53722001_2 - 2.7e-12 46.4 0.2 3.9e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin FliMN_C PF01052.18 001111530.1_53723001_1 - 1.7e-12 47.0 0.2 1.9e-11 43.7 0.2 2.1 2 0 0 2 2 2 1 Type III flagellar switch regulator (C-ring) FliN C-term TOBE PF03459.15 001111530.1_53723001_1 - 0.052 13.7 0.2 0.18 12.0 0.2 1.9 1 0 0 1 1 1 0 TOBE domain VQ PF05678.12 001151140.1_53722001_3 - 3.8e-11 42.1 0.0 9.4e-11 40.9 0.0 1.7 1 0 0 1 1 1 1 VQ motif PC4 PF02229.14 001165553.1_53722001_1 - 2.9e-23 81.1 0.9 4.4e-23 80.5 0.9 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) LEA_3 PF03242.11 001154823.1_53722001_1 - 3e-19 69.4 3.2 5.2e-19 68.6 3.2 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Auxin_inducible PF02519.12 001157534.1_53723001_3 - 8.9e-24 83.4 0.0 2.3e-23 82.1 0.0 1.7 1 1 0 1 1 1 1 Auxin responsive protein Auxin_inducible PF02519.12 001158125.1_53722001_2 - 2.5e-20 72.3 0.0 3.8e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Auxin responsive protein zf-Dof PF02701.13 001157487.1_53723001_1 - 4.9e-33 112.9 10.0 9.4e-33 112.0 10.0 1.5 1 0 0 1 1 1 1 Dof domain, zinc finger FAM199X PF15814.3 001157487.1_53723001_1 - 0.9 8.4 6.0 1.3 7.8 6.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X zf-SNAP50_C PF12251.6 001157487.1_53723001_1 - 1.1 8.8 5.6 1.8 8.1 5.6 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Na_H_Exchanger PF00999.19 001112473.1_53724001_1 - 3.7e-54 183.8 44.1 4.6e-54 183.5 44.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Lig_chan PF00060.24 001112473.1_53724001_1 - 6.4 6.5 9.4 13 5.4 2.9 3.1 2 1 0 2 2 2 0 Ligand-gated ion channel DUF239 PF03080.13 001254823.1_53724001_2 - 3e-76 255.6 0.0 4.2e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF239) DUF4409 PF14365.4 001254823.1_53724001_2 - 2.2e-38 131.2 0.0 3.3e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4409) DUF239 PF03080.13 001254823.1_53724001_3 - 0.00044 19.6 0.0 0.00062 19.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF239) AP2 PF00847.18 001153441.1_53723001_3 - 1.2e-12 47.8 3.0 2.5e-12 46.7 3.0 1.6 1 0 0 1 1 1 1 AP2 domain Abhydrolase_1 PF00561.18 001156522.1_53723001_1 - 1.2e-10 41.4 0.1 7.7e-10 38.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001156522.1_53723001_1 - 2.8e-08 33.2 0.0 4.9e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.18 001156522.1_53723001_1 - 0.032 13.7 0.6 0.054 13.0 0.6 1.3 1 0 0 1 1 1 0 Putative esterase EphA2_TM PF14575.4 001152160.1_53722001_3 - 0.22 12.2 0.5 1.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cytokin-bind PF09265.8 001147183.1_53723001_1 - 2.9e-104 348.3 0.0 3.4e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 001147183.1_53723001_1 - 0.1 12.2 0.3 0.57 9.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain PP2C PF00481.19 001279945.1_53724001_1 - 2.4e-60 204.2 0.0 3.7e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001279945.1_53724001_1 - 0.00022 20.8 2.8 0.00028 20.5 0.1 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C AUX_IAA PF02309.14 001279495.1_53723001_3 - 1.4e-55 188.6 2.8 9.5e-53 179.4 2.8 3.1 1 1 0 1 1 1 1 AUX/IAA family PB1 PF00564.22 001279495.1_53723001_3 - 0.042 13.6 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 PB1 domain ESCRT-II PF05871.10 001279582.1_53722001_3 - 1.4e-38 132.1 0.1 2e-38 131.6 0.1 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit MMM1 PF10296.7 001279582.1_53722001_3 - 0.029 13.3 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 LCAT PF02450.13 001157562.1_53723001_3 - 8.8e-29 100.7 0.0 1e-24 87.3 0.0 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.11 001157562.1_53723001_3 - 0.00067 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.6 001157562.1_53723001_3 - 0.0016 17.6 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.5 001157562.1_53723001_3 - 0.049 14.1 26.3 0.052 14.0 23.4 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2975 PF11188.6 001150393.2_53722001_2 - 0.0072 16.1 0.9 0.0072 16.1 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2975) VQ PF05678.12 001154752.2_53723001_2 - 5.5e-12 44.8 0.0 1.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 VQ motif U-box PF04564.13 001157143.2_53724001_3 - 3.9e-19 68.5 0.0 6.5e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.6 001157143.2_53724001_3 - 0.0097 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit LEA_2 PF03168.11 001316076.1_06922001_2 - 2.4e-11 43.9 0.0 3.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF905 PF06006.10 001316076.1_06922001_2 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) 14-3-3 PF00244.18 001315679.1_06923001_3 - 7.5e-103 342.7 0.3 9.3e-103 342.3 0.3 1.1 1 0 0 1 1 1 1 14-3-3 protein NAM PF02365.13 001315862.1_06923001_1 - 6.9e-25 87.6 0.4 1.5e-24 86.5 0.4 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein Pkinase PF00069.23 001316298.1_06922001_1 - 1.5e-58 198.1 0.0 1.8e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316298.1_06922001_1 - 1.7e-36 125.7 0.0 2.2e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.4 001316298.1_06922001_1 - 7.4e-05 22.3 0.0 0.13 11.7 0.0 2.3 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.21 001316298.1_06922001_1 - 0.00012 21.9 0.0 0.33 10.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.4 001316298.1_06922001_1 - 0.00014 21.2 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.30 001316225.1_06923001_1 - 6.2e-08 33.1 5.0 0.11 13.3 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001316225.1_06923001_1 - 7.5e-05 22.8 0.3 0.075 13.2 0.0 3.5 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain AP2 PF00847.18 001316171.1_06922001_1 - 1.2e-12 47.7 1.8 1.2e-12 47.7 1.8 2.1 2 0 0 2 2 2 1 AP2 domain AP2 PF00847.18 001315843.1_06922001_1 - 1.6e-12 47.4 0.3 1.6e-12 47.4 0.3 1.8 2 0 0 2 2 2 1 AP2 domain DUF1074 PF06382.9 001316269.1_06922001_3 - 0.012 15.7 0.9 0.012 15.7 0.9 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1074) Pkinase PF00069.23 001315696.1_06923001_1 - 1.2e-57 195.1 0.0 1.5e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315696.1_06923001_1 - 1e-31 110.0 0.0 1.4e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001315696.1_06923001_1 - 0.012 14.8 0.0 0.029 13.5 0.0 1.6 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.4 001315696.1_06923001_1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AP2 PF00847.18 001315948.1_06922001_1 - 1.3e-11 44.4 0.1 1.3e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 AP2 domain IF4E PF01652.16 001315948.1_06922001_1 - 0.052 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E FAE1_CUT1_RppA PF08392.10 001316053.1_06924001_3 - 5.5e-140 465.5 0.2 1.1e-139 464.5 0.0 1.5 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.8 001316053.1_06924001_3 - 1.6e-11 44.1 0.0 3.8e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.13 001316053.1_06924001_3 - 1.1e-08 35.1 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.8 001316053.1_06924001_3 - 0.0021 17.7 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.17 001316053.1_06924001_3 - 0.065 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain THP2 PF09432.8 001316053.1_06924001_3 - 0.13 12.2 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Tho complex subunit THP2 Pkinase PF00069.23 001315807.1_06923001_1 - 1.1e-75 254.3 0.0 1.4e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315807.1_06923001_1 - 2.8e-39 134.8 0.0 4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315807.1_06923001_1 - 1.3e-24 86.0 0.1 3.1e-24 84.8 0.1 1.7 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315807.1_06923001_1 - 1.4e-11 44.1 0.0 4.3e-09 36.0 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.12 001315807.1_06923001_1 - 0.014 14.6 0.0 0.043 13.0 0.0 1.6 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001315807.1_06923001_1 - 0.031 14.1 0.0 0.21 11.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L7Ae PF01248.24 001315807.1_06923001_1 - 0.12 12.0 0.1 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hemagglutinin PF00509.16 001315807.1_06923001_1 - 0.15 10.3 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin UBA_4 PF14555.4 001315779.1_06923001_1 - 3.7e-12 45.7 0.8 7.3e-12 44.8 0.8 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.18 001315779.1_06923001_1 - 2.4e-09 37.1 0.0 5.6e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.4 001315779.1_06923001_1 - 8.8e-09 35.3 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like TAP_C PF03943.11 001315779.1_06923001_1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain FAE1_CUT1_RppA PF08392.10 001316162.1_06924001_1 - 6.3e-133 442.4 0.0 7.9e-133 442.1 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.8 001316162.1_06924001_1 - 7.7e-11 41.9 0.0 2.3e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.13 001316162.1_06924001_1 - 3.7e-09 36.6 0.0 7.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.17 001316162.1_06924001_1 - 9.9e-06 25.0 0.1 1.5e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.8 001316162.1_06924001_1 - 4e-05 23.3 0.0 8.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AP2 PF00847.18 001315741.1_06922001_1 - 1.2e-12 47.7 1.8 1.2e-12 47.7 1.8 1.6 2 0 0 2 2 2 1 AP2 domain DUF1509 PF07420.9 001315741.1_06922001_1 - 0.022 13.6 1.6 0.15 10.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) LRR_8 PF13855.4 001316176.1_06928001_1 - 7.4e-46 153.6 76.2 3.6e-08 32.9 3.8 12.3 8 3 3 11 11 11 10 Leucine rich repeat Pkinase PF00069.23 001316176.1_06928001_1 - 2.6e-45 154.7 0.0 3.7e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316176.1_06928001_1 - 1.2e-43 149.1 0.0 1.8e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.5 001316176.1_06928001_1 - 2.2e-42 142.1 76.9 1.6e-07 31.3 0.6 13.3 10 3 4 14 14 14 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001316176.1_06928001_1 - 1.3e-17 61.3 69.4 0.26 11.8 0.1 21.6 20 3 1 21 21 21 5 Leucine Rich Repeat LRR_6 PF13516.4 001316176.1_06928001_1 - 9.5e-14 50.1 66.1 0.53 10.4 0.1 18.8 20 0 0 20 20 20 7 Leucine Rich repeat LRRNT_2 PF08263.10 001316176.1_06928001_1 - 1e-07 32.0 0.1 8.9e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain ABC1 PF03109.14 001316176.1_06928001_1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family LRR_2 PF07723.11 001316176.1_06928001_1 - 0.1 13.2 11.7 3e+02 2.2 0.2 8.9 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_5 PF13306.4 001316176.1_06928001_1 - 1.2 8.9 14.1 0.49 10.2 2.3 4.1 4 0 0 4 4 4 0 Leucine rich repeats (6 copies) Pkinase PF00069.23 001315892.1_06923001_1 - 1e-77 260.9 0.0 2.7e-76 256.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001315892.1_06923001_1 - 1.2e-37 129.5 0.0 1.8e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001315892.1_06923001_1 - 1.3e-17 63.6 3.1 2.6e-17 62.6 3.1 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001315892.1_06923001_1 - 1.8e-06 27.4 0.0 1.3e-05 24.5 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.12 001315892.1_06923001_1 - 0.00098 18.4 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001315892.1_06923001_1 - 0.0028 17.2 0.1 0.0065 15.9 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Phosducin PF02114.14 001315892.1_06923001_1 - 0.011 14.6 0.6 1.8 7.3 0.2 2.3 2 0 0 2 2 2 0 Phosducin APH PF01636.21 001315892.1_06923001_1 - 0.025 14.4 0.1 0.096 12.5 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001315892.1_06923001_1 - 0.033 13.6 0.1 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase ABC1 PF03109.14 001315892.1_06923001_1 - 0.039 14.0 0.2 0.45 10.5 0.0 2.7 3 0 0 3 3 3 0 ABC1 family SRP54_N PF02881.17 001315892.1_06923001_1 - 0.053 13.6 0.4 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain FA_desaturase PF00487.22 001315578.1_06924001_3 - 3.4e-33 115.4 16.1 3.4e-33 115.4 16.1 2.6 3 0 0 3 3 3 1 Fatty acid desaturase Cyt-b5 PF00173.26 001315578.1_06924001_3 - 6.9e-23 80.5 0.1 1.4e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.30 001316114.1_06922001_1 - 1.1e-24 86.1 18.5 0.0001 22.9 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001316114.1_06922001_1 - 0.00041 20.5 0.2 4.1 7.6 0.0 3.7 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 001316114.1_06922001_1 - 0.09 11.2 0.1 1.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Pkinase PF00069.23 001316294.1_06923001_2 - 1e-69 234.7 0.0 1.4e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316294.1_06923001_2 - 4.2e-31 108.0 0.0 6.3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001316294.1_06923001_2 - 6.7e-05 22.2 0.0 0.00059 19.1 0.0 2.2 1 1 2 3 3 3 1 Kinase-like Kdo PF06293.12 001316294.1_06923001_2 - 0.0014 17.9 0.1 0.0022 17.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LTP_2 PF14368.4 001153452.2_53722001_1 - 1.4e-10 41.0 8.9 1.4e-10 41.0 8.9 2.9 3 1 0 3 3 3 1 Probable lipid transfer Tryp_alpha_amyl PF00234.20 001153452.2_53722001_1 - 1.5e-08 34.8 2.8 3.7e-08 33.5 2.8 1.6 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family Kunitz_legume PF00197.16 001287937.1_48622001_2 - 1.6e-35 122.5 0.0 2.1e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor LisH_2 PF16045.3 001288278.1_48623001_2 - 0.059 12.3 0.2 0.1 11.5 0.2 1.4 1 0 0 1 1 1 0 LisH Peptidase_M22 PF00814.23 001288148.1_48623001_2 - 1.6e-90 303.4 0.0 1.9e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.13 001288148.1_48623001_2 - 0.0019 17.8 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus UDPGT PF00201.16 001288088.1_48623001_1 - 1.4e-33 116.3 0.0 3.9e-32 111.6 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Bap31 PF05529.10 001288252.1_48622001_3 - 5.5e-06 26.0 0.1 1.1e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like potato_inhibit PF00280.16 001287906.1_48621001_1 - 3e-19 69.3 0.1 4.1e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.6 001287906.1_48621001_1 - 0.094 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Glyco_hydro_19 PF00182.17 001288193.1_48623001_3 - 2.4e-128 426.7 2.3 2.4e-128 426.7 2.3 1.9 2 0 0 2 2 2 1 Chitinase class I Chitin_bind_1 PF00187.17 001288193.1_48623001_3 - 6.6e-13 48.8 21.1 6.6e-13 48.8 21.1 3.1 4 0 0 4 4 4 1 Chitin recognition protein CarbpepA_inh PF02977.13 001288119.1_48622001_2 - 8.8e-23 79.7 5.7 2.9e-22 78.0 5.7 1.9 1 0 0 1 1 1 1 Carboxypeptidase A inhibitor Phi_1 PF04674.10 001288374.1_48623001_3 - 4.1e-118 393.5 0.5 5e-118 393.2 0.5 1.1 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region Abhydrolase_1 PF00561.18 001288033.1_48623001_1 - 7.2e-20 71.6 0.0 1.2e-19 70.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001288033.1_48623001_1 - 1.9e-18 67.8 0.6 2.5e-18 67.3 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001288033.1_48623001_1 - 4.3e-13 49.0 0.0 5.2e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.9 001288033.1_48623001_1 - 0.0075 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.5 001288033.1_48623001_1 - 0.0076 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme SAM_2 PF07647.15 001288033.1_48623001_1 - 0.12 12.3 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) ATP-synt_C PF00137.19 001288453.1_48622001_2 - 3.1e-34 117.0 36.7 2.5e-20 72.4 13.6 2.3 2 0 0 2 2 2 2 ATP synthase subunit C WRKY PF03106.13 001288009.1_48623001_2 - 1.8e-25 88.9 0.2 1.8e-25 88.9 0.2 2.0 2 0 0 2 2 2 1 WRKY DNA -binding domain Plant_zn_clust PF10533.7 001288009.1_48623001_2 - 4.2e-16 58.5 9.3 4.2e-16 58.5 9.3 2.2 2 0 0 2 2 2 1 Plant zinc cluster domain LEA_2 PF03168.11 001288038.1_48622001_3 - 9.1e-12 45.2 0.0 1.6e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Porin_10 PF14121.4 001288038.1_48622001_3 - 0.00064 18.3 2.5 0.00087 17.9 2.5 1.1 1 0 0 1 1 1 1 Putative porin 2OG-FeII_Oxy PF03171.18 001288483.1_48623001_1 - 5.8e-27 94.0 0.0 9.8e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001288483.1_48623001_1 - 1.9e-19 70.4 0.0 3.1e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Prosystemin PF07376.9 001288108.1_48622001_3 - 1e-112 374.3 37.8 1.3e-112 374.0 37.8 1.1 1 0 0 1 1 1 1 Prosystemin Prot_inhib_II PF02428.13 001288512.1_48622001_1 - 3.5e-33 113.7 36.5 5.6e-18 65.0 15.3 2.6 3 0 0 3 3 3 2 Potato type II proteinase inhibitor family Prot_inhib_II PF02428.13 001287993.1_48622001_1 - 2.2e-36 123.9 36.6 1e-19 70.6 13.5 2.6 3 0 0 3 3 3 2 Potato type II proteinase inhibitor family Epimerase PF01370.19 001288412.1_48623001_3 - 1.1e-59 201.7 0.0 2.1e-59 200.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001288412.1_48623001_3 - 2e-31 109.5 0.0 2.1e-30 106.1 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.13 001288412.1_48623001_3 - 2e-07 30.3 0.0 8.7e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.17 001288412.1_48623001_3 - 9.7e-07 27.9 0.0 2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.10 001288412.1_48623001_3 - 8.6e-05 21.7 0.0 0.0061 15.6 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.4 001288412.1_48623001_3 - 0.00026 20.8 0.0 0.0016 18.3 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.15 001288412.1_48623001_3 - 0.00036 19.6 0.0 0.00061 18.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain UDPG_MGDP_dh_N PF03721.12 001288412.1_48623001_3 - 0.0032 16.9 0.1 0.0087 15.5 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Kunitz_legume PF00197.16 001288014.1_48622001_2 - 3.9e-35 121.3 0.0 4.9e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor zf-RING_2 PF13639.4 001288340.1_48623001_3 - 5.9e-13 48.7 9.5 1.4e-12 47.5 9.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001288340.1_48623001_3 - 5.5e-10 38.7 4.7 5.5e-10 38.7 4.7 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.5 001288340.1_48623001_3 - 7.4e-08 32.4 7.6 1.6e-07 31.4 7.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.4 001288340.1_48623001_3 - 1.6e-06 27.7 9.3 3.1e-06 26.8 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001288340.1_48623001_3 - 3.1e-05 23.6 8.4 7.7e-05 22.4 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001288340.1_48623001_3 - 4.7e-05 23.0 5.2 9.6e-05 22.0 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001288340.1_48623001_3 - 0.00065 19.6 3.0 0.0012 18.7 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.4 001288340.1_48623001_3 - 0.0009 19.0 8.0 0.0017 18.1 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain HemY_N PF07219.11 001288340.1_48623001_3 - 0.0011 19.0 1.1 0.0035 17.4 0.2 2.0 2 0 0 2 2 2 1 HemY protein N-terminus Prok-RING_4 PF14447.4 001288340.1_48623001_3 - 0.01 15.6 8.1 0.022 14.5 8.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.3 001288340.1_48623001_3 - 0.016 14.6 6.8 0.033 13.7 6.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.6 001288340.1_48623001_3 - 0.12 12.5 7.4 1.1 9.4 7.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.9 001288340.1_48623001_3 - 0.16 12.2 8.0 0.36 11.1 8.0 1.6 1 0 0 1 1 1 0 RING-like domain RPE65 PF03055.13 001288034.1_48625001_1 - 1.3e-101 340.7 0.0 2e-101 340.1 0.0 1.3 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Kunitz_legume PF00197.16 001287887.1_48622001_2 - 2e-30 105.9 0.0 2.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor CarbpepA_inh PF02977.13 001288446.1_48622001_1 - 7.6e-22 76.7 7.4 1.3e-21 76.0 7.4 1.4 1 0 0 1 1 1 1 Carboxypeptidase A inhibitor Transposase_24 PF03004.12 001287950.1_48623001_2 - 8.7e-36 123.0 0.2 8.7e-36 123.0 0.2 1.9 2 0 0 2 2 2 1 Plant transposase (Ptta/En/Spm family) Hpt PF01627.21 001287950.1_48623001_2 - 0.12 12.6 0.4 0.96 9.6 0.0 2.4 2 0 0 2 2 2 0 Hpt domain Nop53 PF07767.9 001287950.1_48623001_2 - 2.3 7.4 7.6 2.7 7.2 2.5 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) potato_inhibit PF00280.16 001288517.1_48622001_2 - 8.4e-21 74.3 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Potato inhibitor I family CarbpepA_inh PF02977.13 001288559.1_48622001_2 - 2e-21 75.4 7.4 3.8e-21 74.5 7.4 1.5 1 0 0 1 1 1 1 Carboxypeptidase A inhibitor DUF4710 PF15828.3 001288263.1_48622001_1 - 0.08 12.9 1.4 0.13 12.3 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) RRM_1 PF00076.20 001288263.1_48622001_3 - 1.1e-23 82.6 0.0 5.3e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001288263.1_48622001_3 - 4.1e-13 48.9 0.0 1.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.4 001288263.1_48622001_3 - 0.051 13.3 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DUF4541 PF15074.4 001288263.1_48622001_3 - 0.12 12.9 1.6 1.6 9.2 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) Sulfate_transp PF00916.18 001288497.1_48625001_2 - 1.1e-130 435.7 19.2 1.4e-130 435.3 19.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001288497.1_48625001_2 - 2.6e-33 114.0 0.0 4.4e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.4 001288497.1_48625001_2 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 STAS domain AP2 PF00847.18 001287990.1_48622001_3 - 2.6e-12 46.7 0.0 2.6e-12 46.7 0.0 1.6 2 0 0 2 2 2 1 AP2 domain IF4E PF01652.16 001287990.1_48622001_3 - 0.097 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E Oxidored_molyb PF00174.17 001288380.1_48624001_1 - 6e-54 182.1 0.0 8.7e-54 181.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.14 001288380.1_48624001_1 - 2.5e-37 127.8 0.4 3.9e-37 127.2 0.4 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.18 001288380.1_48624001_1 - 0.05 13.5 0.1 0.31 11.1 0.1 2.4 1 0 0 1 1 1 0 BNR/Asp-box repeat Entericidin PF08085.9 001288380.1_48624001_1 - 0.44 10.5 0.0 0.44 10.5 0.0 2.2 3 0 0 3 3 3 0 Entericidin EcnA/B family Arf PF00025.19 001288237.1_48622001_1 - 3e-63 212.3 0.0 3.9e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.18 001288237.1_48622001_1 - 6.2e-08 32.1 0.1 0.00033 19.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.11 001288237.1_48622001_1 - 3.9e-07 30.2 0.0 7.7e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 001288237.1_48622001_1 - 1.7e-06 27.6 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.21 001288237.1_48622001_1 - 2.1e-06 27.6 0.0 3.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.8 001288237.1_48622001_1 - 8.1e-06 25.3 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001288237.1_48622001_1 - 0.0009 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.7 001288237.1_48622001_1 - 0.0065 16.1 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Antibiotic_NAT PF02522.12 001288237.1_48622001_1 - 0.19 11.3 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase CPP1-like PF11833.6 001288444.1_48623001_2 - 2.8e-60 203.2 0.1 3.7e-60 202.8 0.1 1.2 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like CBM_48 PF02922.16 001287875.1_48626001_1 - 2.5e-14 53.3 0.0 2.8e-13 49.9 0.0 2.7 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.22 001287875.1_48626001_1 - 2.9e-11 43.4 0.0 1.3e-08 34.7 0.0 3.0 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Pkinase PF00069.23 001288477.1_48623001_1 - 5.8e-64 215.9 0.0 6.9e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288477.1_48623001_1 - 1.5e-34 119.3 0.0 2.2e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001288477.1_48623001_1 - 0.00013 21.3 0.0 0.00026 20.3 0.0 1.4 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.4 001288477.1_48623001_1 - 0.017 14.6 0.0 4.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.21 001288477.1_48623001_1 - 0.021 14.6 0.0 0.5 10.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C2H2_6 PF13912.4 001288304.1_48622001_1 - 5.7e-25 86.6 5.8 3.4e-12 45.9 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.4 001288304.1_48622001_1 - 5.5e-08 32.9 5.5 0.00086 19.8 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.24 001288304.1_48622001_1 - 1.8e-05 24.8 4.1 0.046 14.1 0.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.6 001288304.1_48622001_1 - 7.4e-05 22.8 0.1 0.37 11.0 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.4 001288304.1_48622001_1 - 0.0055 17.0 4.6 0.4 11.1 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_8 PF15909.3 001288304.1_48622001_1 - 0.016 15.4 0.4 2.1 8.5 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.5 001288304.1_48622001_1 - 0.14 12.4 0.5 7.3 6.9 0.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.5 001288304.1_48622001_1 - 0.21 11.9 5.4 2.6 8.4 0.4 3.0 2 1 0 2 2 2 0 Zinc-finger of C2H2 type EF-hand_1 PF00036.30 001288354.1_48623001_2 - 1.5e-17 61.6 9.8 3.5e-05 22.9 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001288354.1_48623001_2 - 9.2e-15 53.1 10.2 9e-05 22.0 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001288354.1_48623001_2 - 3.3e-13 48.3 10.4 5.6e-06 25.5 0.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.4 001288354.1_48623001_2 - 8.5e-11 42.0 8.0 2.4e-08 34.2 0.9 3.4 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.4 001288354.1_48623001_2 - 4.4e-05 23.0 8.0 0.0055 16.3 0.4 3.8 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.5 001288354.1_48623001_2 - 0.038 13.8 3.5 0.18 11.6 0.2 2.4 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001288354.1_48623001_2 - 0.068 13.4 3.2 0.081 13.1 0.5 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.4 001288354.1_48623001_2 - 0.089 13.0 0.0 0.34 11.1 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain CarbpepA_inh PF02977.13 001288492.1_48622001_1 - 4.3e-21 74.3 7.8 7.2e-21 73.6 7.8 1.4 1 0 0 1 1 1 1 Carboxypeptidase A inhibitor Arf PF00025.19 001288046.1_48622001_2 - 3.1e-74 248.0 0.2 3.8e-74 247.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.11 001288046.1_48622001_2 - 2.2e-12 47.1 0.0 3.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.8 001288046.1_48622001_2 - 3.1e-12 46.2 0.0 4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.18 001288046.1_48622001_2 - 1.5e-11 43.9 0.8 2.9e-07 29.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.10 001288046.1_48622001_2 - 1e-09 38.0 0.0 1.3e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.20 001288046.1_48622001_2 - 1.3e-09 37.8 0.0 1.6e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.21 001288046.1_48622001_2 - 0.00049 20.0 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 001288046.1_48622001_2 - 0.094 11.9 0.5 0.16 11.2 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.25 001288046.1_48622001_2 - 0.12 11.8 0.2 4.9 6.5 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Glycolytic PF00274.17 001288450.1_48623001_3 - 3.2e-174 578.5 0.0 3.6e-174 578.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Prosystemin PF07376.9 001287981.1_48622001_2 - 2.6e-122 405.7 35.2 3e-122 405.5 35.2 1.0 1 0 0 1 1 1 1 Prosystemin Pkinase PF00069.23 001288184.1_48624001_2 - 8.6e-73 244.8 0.0 1.2e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288184.1_48624001_2 - 4.2e-33 114.6 0.0 6.1e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001288184.1_48624001_2 - 2e-05 23.9 0.0 5.2e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.12 001288184.1_48624001_2 - 0.00025 20.3 0.2 0.00041 19.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family S6PP PF05116.11 001288181.1_48624001_1 - 8.6e-103 343.0 0.0 1.1e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase S6PP_C PF08472.8 001288181.1_48624001_1 - 5.1e-56 188.0 0.0 9.9e-56 187.1 0.0 1.5 1 0 0 1 1 1 1 Sucrose-6-phosphate phosphohydrolase C-terminal Hydrolase_3 PF08282.10 001288181.1_48624001_1 - 1.8e-17 63.8 0.0 3.3e-14 53.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PMM PF03332.11 001288181.1_48624001_1 - 0.0017 18.1 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Trehalose_PPase PF02358.14 001288181.1_48624001_1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Trehalose-phosphatase HSP20 PF00011.19 001288210.1_48622001_2 - 1.1e-26 92.7 0.4 1.6e-26 92.3 0.4 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.14 001288210.1_48622001_2 - 1.9e-05 25.5 0.2 2.8e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 CS domain 2OG-FeII_Oxy PF03171.18 001288179.1_48623001_1 - 1.2e-28 99.4 0.0 2.3e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001288179.1_48623001_1 - 7.3e-22 78.2 0.0 1.1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Remorin_C PF03763.11 001288026.1_48622001_1 - 4.6e-29 100.3 22.8 4.6e-29 100.3 22.8 1.6 2 0 0 2 2 2 1 Remorin, C-terminal region Remorin_N PF03766.11 001288026.1_48622001_1 - 1.1e-11 44.4 10.0 1.1e-11 44.4 10.0 2.5 3 0 0 3 3 3 1 Remorin, N-terminal region DRY_EERY PF09750.7 001288026.1_48622001_1 - 3.4 7.8 7.8 5.8 7.0 7.8 1.3 1 0 0 1 1 1 0 Alternative splicing regulator TAXi_C PF14541.4 001287952.1_48623001_1 - 2.5e-48 163.7 0.0 3.8e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.4 001287952.1_48623001_1 - 2.6e-34 118.9 0.1 4.4e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Cytokin-bind PF09265.8 001288472.1_48624001_2 - 1.8e-116 388.4 1.6 2.2e-116 388.0 1.6 1.1 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 001288472.1_48624001_2 - 1.6e-18 66.6 0.1 2.5e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.17 001288472.1_48624001_2 - 0.017 14.6 0.1 0.033 13.7 0.1 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain 2OG-FeII_Oxy PF03171.18 001287930.1_48623001_1 - 1.4e-24 86.4 0.0 6e-24 84.3 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001287930.1_48623001_1 - 1.9e-23 83.3 0.1 5.1e-23 82.0 0.1 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ins134_P3_kin PF05770.9 001287863.1_48623001_1 - 2.6e-123 411.0 0.1 3e-123 410.8 0.1 1.0 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase Ribosomal_S3_C PF00189.18 001288505.1_48622001_1 - 1.7e-17 63.6 0.0 4.9e-17 62.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.15 001288505.1_48622001_1 - 2.5e-12 46.3 0.5 4e-12 45.7 0.5 1.3 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.3 001288505.1_48622001_1 - 0.092 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus potato_inhibit PF00280.16 001288335.1_48621001_1 - 4.5e-18 65.5 0.0 6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family potato_inhibit PF00280.16 001288056.1_48621001_1 - 2e-22 79.5 0.0 3.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Potato inhibitor I family CaM_binding PF07839.9 001288478.1_48629001_2 - 1.9e-62 209.1 15.0 9.9e-33 113.2 3.0 7.0 7 2 1 8 8 8 2 Plant calmodulin-binding domain Membr_traf_MHD PF10540.7 001288478.1_48629001_2 - 0.024 14.8 1.0 0.18 12.0 0.8 2.6 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain Pkinase PF00069.23 001287835.1_48625001_1 - 2.3e-65 220.5 0.0 3.1e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001287835.1_48625001_1 - 1.3e-25 86.8 1.7 2.3e-05 23.5 0.0 4.6 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001287835.1_48625001_1 - 3.3e-25 88.7 0.0 4.8e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_5 PF13202.4 001287835.1_48625001_1 - 2.9e-24 83.3 4.1 2.5e-06 26.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001287835.1_48625001_1 - 1.1e-20 71.6 0.6 7.3e-05 22.3 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001287835.1_48625001_1 - 9.1e-20 70.8 1.9 3.5e-09 36.9 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.4 001287835.1_48625001_1 - 5.1e-12 45.2 0.5 2.1e-05 24.1 0.0 3.3 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001287835.1_48625001_1 - 3.1e-08 33.8 0.2 9.5e-05 22.6 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.4 001287835.1_48625001_1 - 2.4e-06 27.0 0.0 2.2e-05 23.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001287835.1_48625001_1 - 0.0012 18.7 0.0 1.4 8.7 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.12 001287835.1_48625001_1 - 0.062 12.5 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.5 001287835.1_48625001_1 - 0.074 12.9 2.2 3.2 7.6 0.3 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand TAXi_C PF14541.4 001288035.1_48623001_1 - 1.1e-53 181.2 0.0 1.6e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.4 001288035.1_48623001_1 - 2.8e-41 141.6 1.4 3.9e-41 141.1 1.4 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Patatin PF01734.20 001287884.1_48622001_1 - 1.6e-20 74.0 0.1 3.4e-20 73.0 0.1 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase AP2 PF00847.18 001288508.1_48622001_1 - 6.1e-14 51.9 4.9 6.5e-14 51.8 2.8 1.9 2 0 0 2 2 2 1 AP2 domain Tubulin PF00091.23 001288543.1_48624001_1 - 4.4e-34 118.3 0.0 6.1e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FixQ PF05545.9 001288543.1_48624001_1 - 0.071 12.9 3.0 0.15 11.9 3.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Tubulin_C PF03953.15 001288543.1_48624001_2 - 7.6e-41 139.2 0.0 1.5e-40 138.2 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin PF00091.23 001288543.1_48624001_3 - 3.9e-25 89.1 0.0 5.5e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001288543.1_48624001_3 - 0.0024 18.0 0.1 0.0039 17.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Terpene_synth_C PF03936.14 001288154.1_48624001_1 - 2e-103 345.3 6.5 2.8e-103 344.8 6.5 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001288154.1_48624001_1 - 2.5e-56 190.2 1.3 4.8e-56 189.3 1.3 1.5 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain Intron_maturas2 PF01348.19 001288154.1_48624001_1 - 0.022 14.6 0.0 0.082 12.7 0.0 2.0 2 0 0 2 2 2 0 Type II intron maturase DUF2650 PF10853.6 001288154.1_48624001_2 - 8.5 6.1 7.8 3.1 7.5 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2650) Ribosomal_L27A PF00828.17 001288685.1_48622001_2 - 8.1e-21 74.8 0.0 1.2e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L11_N PF03946.12 001288671.1_48622001_1 - 1e-22 79.5 0.1 1.8e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.17 001288671.1_48622001_1 - 3.4e-20 72.2 0.4 6.5e-20 71.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain AP2 PF00847.18 001288690.1_48622001_1 - 2.4e-11 43.6 1.8 3.4e-11 43.1 1.8 1.2 1 0 0 1 1 1 1 AP2 domain Prolactin_RP PF15172.4 001288690.1_48622001_1 - 0.044 13.3 2.6 0.088 12.3 2.6 1.4 1 0 0 1 1 1 0 Prolactin-releasing peptide LTP_2 PF14368.4 001288696.1_48622001_1 - 2.6e-07 30.5 6.6 2.6e-07 30.5 6.6 1.5 2 0 0 2 2 2 1 Probable lipid transfer Mito_carr PF00153.25 001147601.1_53724001_1 - 8.6e-65 214.6 2.5 1.3e-21 76.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4408 PF14364.4 001165431.1_53722001_2 - 7.6e-12 44.6 0.6 1.5e-11 43.7 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4408) tRNA_synt_1c_R1 PF04558.13 001165431.1_53722001_2 - 0.021 14.7 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF761 PF05553.9 001165431.1_53722001_2 - 0.038 13.4 0.5 0.064 12.7 0.5 1.3 1 0 0 1 1 1 0 Cotton fibre expressed protein HSP20 PF00011.19 001154925.1_53722001_3 - 1.7e-32 111.4 1.5 2.5e-32 110.9 1.5 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family AJAP1_PANP_C PF15298.4 001165447.1_53724001_1 - 0.048 13.7 0.1 9.9 6.2 0.1 2.3 2 0 0 2 2 2 0 AJAP1/PANP C-terminus PRIMA1 PF16101.3 001150008.2_53722001_3 - 6.2 6.7 10.8 2.3 8.1 7.5 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FAM199X PF15814.3 001150939.2_53723001_2 - 6.4 5.6 6.3 9 5.1 6.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X HemY_N PF07219.11 001150939.2_53723001_3 - 0.48 10.5 7.3 0.23 11.5 3.4 2.3 2 0 0 2 2 2 0 HemY protein N-terminus TPR_2 PF07719.15 001176187.1_53724001_1 - 1.5e-05 24.6 0.8 0.33 11.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.4 001176187.1_53724001_1 - 9.9e-05 22.1 0.2 0.87 9.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.26 001176187.1_53724001_1 - 0.00012 21.6 1.0 0.29 10.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.4 001176187.1_53724001_1 - 0.0016 18.4 0.1 0.0042 17.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001176187.1_53724001_1 - 0.099 12.7 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 LON_substr_bdg PF02190.14 001176187.1_53724001_2 - 7.1e-23 81.4 0.0 9.5e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-A20 PF01754.14 001112788.1_53721001_3 - 6.7e-13 48.2 4.5 6.7e-13 48.2 4.5 2.4 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.14 001112788.1_53721001_3 - 3.2e-10 39.9 6.7 3.2e-10 39.9 6.7 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger UDPGT PF00201.16 001279517.1_53723001_3 - 1e-28 100.3 0.2 1.4e-28 99.9 0.2 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001279517.1_53723001_3 - 0.081 12.8 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PI-PLC-X PF00388.17 001317844.1_53724001_3 - 5.4e-06 25.9 0.0 8.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glyco_hydro_1 PF00232.16 001112398.2_53725001_1 - 7.7e-56 189.3 0.4 3e-31 108.2 0.2 2.6 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Cellulase PF00150.16 001112398.2_53725001_1 - 2.9e-05 23.5 0.0 0.00018 20.9 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Oleosin PF01277.15 001315556.1_06922001_2 - 5.4e-38 129.1 3.3 1.2e-37 127.9 3.3 1.6 1 0 0 1 1 1 1 Oleosin IncA PF04156.12 001315556.1_06922001_2 - 0.26 10.9 7.5 0.41 10.3 7.5 1.4 1 0 0 1 1 1 0 IncA protein Phage_holin_3_6 PF07332.9 001315556.1_06922001_2 - 0.46 10.4 5.7 0.78 9.7 5.7 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TFIID-31kDa PF02291.13 001288297.1_48623001_3 - 1.6e-46 157.2 0.0 2.1e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.4 001288297.1_48623001_3 - 2.8e-05 24.3 0.1 5.2e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.22 001288297.1_48623001_3 - 0.0054 17.0 0.3 0.016 15.5 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.11 001288297.1_48623001_3 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.4 001288297.1_48623001_3 - 0.012 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Band_7 PF01145.23 001288687.1_48622001_1 - 1e-20 74.3 1.3 1.8e-20 73.6 1.3 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.6 001288687.1_48622001_1 - 0.00012 21.1 1.9 0.00016 20.8 1.9 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Histone PF00125.22 001288692.1_48622001_3 - 1.1e-22 80.7 4.2 1.5e-22 80.3 4.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001288692.1_48622001_3 - 0.00022 21.3 0.0 0.00063 19.9 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.3 001288692.1_48622001_3 - 0.006 16.5 1.9 0.0083 16.0 1.9 1.2 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.11 001288692.1_48622001_3 - 0.037 14.4 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RP-C PF03428.11 001288692.1_48622001_3 - 0.062 12.8 0.1 3.3 7.2 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Hydrophob_seed PF14547.4 001288691.1_48621001_1 - 1.3e-29 102.0 7.9 1.3e-29 102.0 7.9 1.4 2 0 0 2 2 2 1 Hydrophobic seed protein Tryp_alpha_amyl PF00234.20 001288691.1_48621001_1 - 7e-06 26.3 0.7 1.1e-05 25.7 0.7 1.3 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family DUF106 PF01956.14 001288701.1_48622001_1 - 1.7e-30 105.9 0.3 2.1e-30 105.6 0.3 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 DUF948 PF06103.9 001288701.1_48622001_1 - 0.4 10.8 0.1 0.4 10.8 0.1 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) adh_short_C2 PF13561.4 001150783.2_53723001_3 - 1.8e-59 201.0 2.5 2.3e-59 200.7 2.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001150783.2_53723001_3 - 3.8e-44 150.3 0.2 4.9e-44 150.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001150783.2_53723001_3 - 3.3e-13 49.8 1.0 1.3e-12 47.8 1.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.19 001150783.2_53723001_3 - 6e-05 22.5 0.5 0.00034 20.0 0.5 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001150783.2_53723001_3 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 001150783.2_53723001_3 - 0.0082 15.9 2.9 0.02 14.7 2.9 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.13 001150783.2_53723001_3 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AdoHcyase_NAD PF00670.19 001150783.2_53723001_3 - 0.086 12.8 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.14 001150783.2_53723001_3 - 0.13 11.7 0.6 0.25 10.8 0.6 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.19 001150783.2_53723001_3 - 0.56 9.4 3.2 0.55 9.4 0.9 2.0 2 1 0 2 2 2 0 ThiF family CTP_transf_like PF01467.24 001315769.1_06923001_3 - 1.4e-32 112.7 0.2 2.8e-32 111.7 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like LMBR1 PF04791.14 001315769.1_06923001_3 - 0.51 9.0 7.0 0.64 8.7 6.0 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein Staygreen PF12638.5 001315884.1_06922001_1 - 2.3e-60 202.5 0.0 3.2e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Staygreen protein AAA PF00004.27 001316246.1_06923001_1 - 1.9e-12 47.6 0.0 3.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc PF14363.4 001316246.1_06923001_1 - 5e-11 42.7 0.1 1.2e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 Domain associated at C-terminal with AAA DUF815 PF05673.11 001316246.1_06923001_1 - 3.4e-05 23.0 0.0 5.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.4 001316246.1_06923001_1 - 0.00056 20.2 0.0 0.0037 17.5 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.4 001316246.1_06923001_1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.12 001316246.1_06923001_1 - 0.0038 17.1 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.4 001316246.1_06923001_1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.10 001316246.1_06923001_1 - 0.0096 15.1 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.4 001316246.1_06923001_1 - 0.016 15.4 0.1 0.18 12.0 0.0 2.5 3 1 1 4 4 3 0 AAA domain DUF2722 PF10846.6 001316246.1_06923001_1 - 0.035 12.9 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PPV_E1_C PF00519.15 001316246.1_06923001_1 - 0.049 12.3 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_PrkA PF08298.9 001316246.1_06923001_1 - 0.055 12.2 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain TsaE PF02367.15 001316246.1_06923001_1 - 0.059 13.2 0.0 0.54 10.1 0.0 2.3 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.20 001316246.1_06923001_1 - 0.066 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.14 001316246.1_06923001_1 - 0.073 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.25 001316246.1_06923001_1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter WPP PF13943.4 001288358.1_48624001_1 - 3.1e-35 120.4 0.1 7.6e-35 119.1 0.1 1.7 1 0 0 1 1 1 1 WPP domain LRR_6 PF13516.4 001288358.1_48624001_1 - 2.2e-20 70.8 7.3 0.016 15.1 0.0 10.1 10 0 0 10 10 10 7 Leucine Rich repeat LRR_4 PF12799.5 001288358.1_48624001_1 - 4.2e-13 49.1 3.3 0.0031 17.7 0.1 7.2 5 1 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001288358.1_48624001_1 - 1.6e-05 24.6 3.0 4.7 8.0 0.0 6.9 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.4 001288358.1_48624001_1 - 0.059 13.0 7.6 2.8 7.6 0.5 5.7 4 3 0 4 4 4 0 Leucine rich repeat Pro_isomerase PF00160.19 001288676.1_48622001_1 - 4.6e-48 163.3 0.1 5.1e-48 163.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_5 PF13893.4 001318683.1_48624001_3 - 6.3e-40 135.5 1.1 7.1e-29 99.8 0.0 3.9 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 001318683.1_48624001_3 - 7.5e-32 108.8 0.1 4.4e-09 35.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001318683.1_48624001_3 - 3.8e-08 32.9 1.2 0.011 15.5 0.1 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.3 001318683.1_48624001_3 - 0.017 15.1 0.0 2.4 8.2 0.0 3.5 3 0 0 3 3 3 0 RNA recognition motif DPBB_1 PF03330.16 001318550.1_48622001_1 - 0.0024 18.0 0.0 0.012 15.8 0.0 2.1 1 1 0 1 1 1 1 Lytic transglycolase CarbpepA_inh PF02977.13 001318550.1_48622001_1 - 0.0079 15.8 6.9 0.021 14.5 6.9 1.7 1 0 0 1 1 1 1 Carboxypeptidase A inhibitor Nodulin_late PF07127.9 001318550.1_48622001_1 - 0.3 11.3 6.6 0.081 13.1 1.7 2.3 2 0 0 2 2 2 0 Late nodulin protein Chloroa_b-bind PF00504.19 001318687.1_48622001_1 - 1.4e-50 171.9 0.0 1.6e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PhosphMutase PF10143.7 001318687.1_48622001_1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Pyridoxal_deC PF00282.17 001318615.1_48624001_1 - 2.2e-109 365.5 0.0 2.8e-109 365.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.19 001318615.1_48624001_1 - 0.00049 19.3 0.0 0.00078 18.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.11 001318615.1_48624001_1 - 0.003 16.2 0.0 0.0056 15.3 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Replicase PF03090.15 001318615.1_48624001_1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Replicase family ADH_N PF08240.10 001318602.1_48623001_2 - 3.6e-27 94.3 4.4 5.8e-27 93.6 4.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.24 001318602.1_48623001_2 - 1.4e-19 70.1 0.1 2.3e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.17 001318602.1_48623001_2 - 1.2e-05 24.6 0.1 2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.19 001318602.1_48623001_2 - 4.7e-05 22.7 0.1 9.4e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.4 001318602.1_48623001_2 - 0.00045 21.1 0.0 0.00076 20.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.18 001318602.1_48623001_2 - 0.021 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.13 001318602.1_48623001_2 - 0.022 14.8 0.2 0.039 14.0 0.2 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.16 001318602.1_48623001_2 - 0.028 14.2 0.2 0.042 13.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.4 001318602.1_48623001_2 - 0.05 13.9 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.25 001318602.1_48623001_2 - 1.6 9.2 4.4 0.36 11.3 0.9 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.23 001318608.1_48622001_1 - 6.6e-73 245.2 0.0 7.4e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001318608.1_48622001_1 - 4.9e-32 111.1 0.0 5.8e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001318608.1_48622001_1 - 2.5e-09 36.8 0.0 3.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001318608.1_48622001_1 - 0.0021 17.3 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001318608.1_48622001_1 - 0.017 14.9 0.0 0.043 13.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Tubulin PF00091.23 001318688.1_48624001_1 - 8.9e-68 228.2 0.0 1.2e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001318688.1_48624001_1 - 5.5e-51 171.9 0.1 8.3e-51 171.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001318688.1_48624001_1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Lyase_aromatic PF00221.17 001318638.1_48625001_2 - 7.5e-151 502.8 2.2 9.6e-151 502.5 2.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Sel_put PF04328.11 001318638.1_48625001_2 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein, putative Phosphoesterase PF04185.12 001318644.1_48623001_1 - 1.9e-59 201.6 0.3 2.4e-59 201.2 0.3 1.1 1 0 0 1 1 1 1 Phosphoesterase family Usp PF00582.24 001318644.1_48623001_1 - 2.6e-13 50.6 0.0 3.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family Sulfatase PF00884.21 001318644.1_48623001_1 - 1.7e-06 27.5 0.1 5e-06 26.0 0.1 1.6 1 1 1 2 2 2 1 Sulfatase UDPGT PF00201.16 001287870.1_48624001_1 - 3.8e-18 65.4 0.0 7e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001287870.1_48624001_1 - 0.045 13.6 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.4 001287870.1_48624001_1 - 0.17 11.0 0.1 0.26 10.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 AP2 PF00847.18 001318649.1_48622001_1 - 4.9e-12 45.8 0.8 7.7e-12 45.2 0.8 1.3 1 0 0 1 1 1 1 AP2 domain Pkinase PF00069.23 001318594.1_48623001_1 - 3.6e-69 232.9 0.0 5.1e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001318594.1_48623001_1 - 8.9e-31 107.0 0.0 1.4e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.18 001318594.1_48623001_1 - 0.0056 16.1 0.1 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase RNA_pol_3_Rpc31 PF11705.6 001318594.1_48623001_1 - 0.054 13.6 2.8 0.084 13.0 2.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 APH PF01636.21 001318594.1_48623001_1 - 0.15 11.8 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kunitz_legume PF00197.16 001318627.1_48622001_1 - 2.8e-34 118.4 0.0 3.3e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor UDPGT PF00201.16 001318617.1_48623001_1 - 2.8e-27 95.6 0.1 1.6e-26 93.1 0.1 1.9 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF4011 PF13195.4 001318617.1_48623001_1 - 0.077 12.8 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) DUF296 PF03479.13 001318559.1_48622001_1 - 1.2e-21 76.9 0.0 1.9e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF296) Phytochelatin_C PF09328.8 001318668.1_48624001_3 - 3.2e-123 410.1 0.6 5.2e-123 409.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1984) Phytochelatin PF05023.12 001318668.1_48624001_3 - 3.5e-83 277.9 0.0 5.5e-83 277.3 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.4 001318668.1_48624001_3 - 0.0034 17.8 0.2 0.18 12.2 0.0 2.9 3 0 0 3 3 3 1 Peptidase_C39 like family Peptidase_C39 PF03412.13 001318668.1_48624001_3 - 0.13 12.0 0.0 5.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Peptidase C39 family FNIP_M PF14637.4 001318668.1_48624001_3 - 0.13 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain WRKY PF03106.13 001318555.1_48623001_1 - 1.2e-52 175.9 18.0 2.2e-26 91.8 4.9 2.4 2 0 0 2 2 2 2 WRKY DNA -binding domain FLYWCH PF04500.14 001318555.1_48623001_1 - 0.0077 16.2 2.0 0.61 10.1 0.2 2.4 2 0 0 2 2 2 2 FLYWCH zinc finger domain ICAM_N PF03921.12 001318555.1_48623001_1 - 0.074 12.6 0.2 1.7 8.2 0.0 2.8 2 1 1 3 3 3 0 Intercellular adhesion molecule (ICAM), N-terminal domain FAR1 PF03101.13 001318555.1_48623001_1 - 0.52 10.9 3.2 3.2 8.4 0.7 2.6 2 1 0 2 2 2 0 FAR1 DNA-binding domain Ogr_Delta PF04606.10 001318555.1_48623001_1 - 0.61 10.0 4.2 0.99 9.3 0.1 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger AMPK1_CBM PF16561.3 001318610.1_48623001_3 - 1.9e-29 101.6 0.0 3e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.13 001318610.1_48623001_3 - 1.1e-19 70.3 0.2 2.3e-19 69.3 0.2 1.6 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AP2 PF00847.18 001318551.1_48622001_1 - 7.9e-15 54.7 1.2 1.5e-14 53.9 1.2 1.5 1 0 0 1 1 1 1 AP2 domain AP2 PF00847.18 001318670.1_48623001_1 - 4.5e-11 42.7 2.5 1e-10 41.6 2.5 1.6 1 0 0 1 1 1 1 AP2 domain Acetyltransf_1 PF00583.23 001318552.1_48622001_1 - 4.5e-06 26.7 0.0 6.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.5 001318552.1_48622001_1 - 0.071 13.2 0.5 5.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain UFD1 PF03152.12 001318676.1_48623001_3 - 4.5e-81 270.3 0.0 5.7e-81 269.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF5088 PF17008.3 001318676.1_48623001_3 - 0.092 12.3 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5088) DUF260 PF03195.12 001318635.1_48622001_1 - 5.8e-23 81.0 0.0 9.4e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF260 Reticulon PF02453.15 001318541.1_48623001_2 - 1.4e-54 184.1 4.9 2e-54 183.6 4.9 1.2 1 0 0 1 1 1 1 Reticulon NAP PF00956.16 001318698.1_48622001_1 - 6.7e-32 110.6 10.8 1.3e-27 96.5 0.9 2.8 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) SecA_SW PF07516.11 001318698.1_48622001_1 - 0.0092 15.9 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 SecA Wing and Scaffold domain OmpH PF03938.12 001318698.1_48622001_1 - 0.064 13.1 5.4 0.11 12.3 5.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2570 PF10828.6 001318698.1_48622001_1 - 0.077 12.7 2.6 0.079 12.7 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Sigma70_ner PF04546.11 001318698.1_48622001_1 - 0.16 11.7 23.0 1 9.1 16.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region TMPIT PF07851.11 001318698.1_48622001_1 - 0.23 10.5 0.9 0.28 10.2 0.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein C2 PF00168.28 001318645.1_48622001_1 - 1.4e-09 38.0 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain DUF2076 PF09849.7 001318645.1_48622001_1 - 0.0013 18.7 6.7 0.0021 18.0 6.7 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) PI3K_C2 PF00792.22 001318645.1_48622001_1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 SSB PF00436.23 001318576.1_48623001_3 - 9.1e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family Glyco_hydro_19 PF00182.17 001318545.1_48622001_2 - 2.5e-111 371.0 7.7 1.1e-110 368.9 7.7 1.8 1 1 0 1 1 1 1 Chitinase class I Myb_DNA-binding PF00249.29 001318562.1_48623001_1 - 2.2e-35 120.4 1.0 3.8e-18 65.2 0.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001318562.1_48623001_1 - 9e-27 93.0 0.4 4.5e-18 65.1 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001318562.1_48623001_1 - 1.7e-05 24.7 4.3 0.026 14.4 0.0 3.3 3 1 0 4 4 4 2 SLIDE Serglycin PF04360.10 001318562.1_48623001_1 - 0.0064 16.3 0.5 0.0064 16.3 0.5 2.0 2 0 0 2 2 2 1 Serglycin Rap1_C PF11626.6 001318562.1_48623001_1 - 0.29 11.1 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain OAD_gamma PF04277.11 001318562.1_48623001_1 - 0.55 10.7 3.1 6.3 7.3 4.6 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain p450 PF00067.20 001318569.1_48623001_1 - 1.9e-18 66.3 0.0 7e-17 61.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 WD40 PF00400.30 001318622.1_48623001_1 - 6.5e-10 39.3 1.4 0.031 15.0 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001318622.1_48623001_1 - 1.9e-05 24.7 0.2 0.18 12.0 0.0 3.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain ADH_zinc_N PF00107.24 001318568.1_48623001_2 - 9.7e-24 83.6 0.1 1.6e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001318568.1_48623001_2 - 2.4e-23 81.9 0.2 5e-23 80.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.3 001318568.1_48623001_2 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.19 001318568.1_48623001_2 - 0.0011 18.1 1.9 0.0021 17.2 1.9 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.4 001318568.1_48623001_2 - 0.0035 18.2 0.0 0.0063 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.12 001318568.1_48623001_2 - 0.053 13.0 0.6 0.11 12.0 0.6 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.17 001318568.1_48623001_2 - 0.14 11.3 0.2 0.24 10.6 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Myb_DNA-binding PF00249.29 001318609.1_48622001_1 - 9.4e-32 108.8 0.9 1.4e-15 57.0 0.8 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001318609.1_48622001_1 - 1.5e-17 63.4 0.1 4.3e-09 36.4 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Bax1-I PF01027.18 001318656.1_48622001_1 - 4.3e-49 167.0 31.9 4.9e-49 166.8 31.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.7 001318656.1_48622001_1 - 0.58 8.2 23.2 0.73 7.9 23.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Myb_DNA-binding PF00249.29 001318681.1_48623001_1 - 4.9e-38 128.9 1.4 4.6e-20 71.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001318681.1_48623001_1 - 1.6e-27 95.4 1.0 7.8e-18 64.3 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001318681.1_48623001_1 - 0.0002 21.2 0.2 0.67 9.9 0.0 3.1 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.3 001318681.1_48623001_1 - 0.0011 18.6 0.6 0.36 10.6 0.0 2.9 2 1 1 3 3 3 2 Myb DNA-binding like TFIIA PF03153.11 001318681.1_48623001_1 - 0.97 9.2 11.1 1.3 8.8 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.3 001318681.1_48623001_1 - 4.6 7.2 13.0 5.5 6.9 10.4 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF568 PF04526.11 001318598.1_48624001_1 - 1.2e-23 83.5 0.1 5.7e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF568) Cytochrom_B561 PF03188.14 001318598.1_48624001_1 - 9.4e-06 25.7 4.2 1.3e-05 25.2 1.9 2.4 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 ADH_zinc_N PF00107.24 001318570.1_48623001_1 - 6.2e-33 113.3 0.9 9.9e-33 112.7 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.4 001318570.1_48623001_1 - 9e-26 91.4 0.0 1.4e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001318570.1_48623001_1 - 5.7e-10 38.9 1.2 5.7e-09 35.7 0.1 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.23 001318570.1_48623001_1 - 0.0023 17.3 0.1 0.004 16.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD-GH PF10712.7 001318570.1_48623001_1 - 0.2 10.0 0.0 0.25 9.6 0.0 1.1 1 0 0 1 1 1 0 NAD-specific glutamate dehydrogenase OAD_gamma PF04277.11 001318570.1_48623001_2 - 0.24 11.9 6.5 0.41 11.1 6.5 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AP3D1 PF06375.9 001318570.1_48623001_2 - 0.79 9.9 15.1 1.2 9.3 15.1 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 UDPGT PF00201.16 001318679.1_48623001_1 - 7.4e-25 87.6 0.1 2.9e-24 85.6 0.1 1.9 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001318679.1_48623001_1 - 0.0013 18.6 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF432 PF04254.11 001318679.1_48623001_1 - 0.076 13.1 0.0 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF432) WRKY PF03106.13 001318613.1_48625001_1 - 1.7e-50 169.0 12.0 7e-26 90.2 4.1 2.6 2 0 0 2 2 2 2 WRKY DNA -binding domain FLYWCH PF04500.14 001318613.1_48625001_1 - 0.085 12.9 0.8 0.46 10.5 0.5 2.2 2 0 0 2 2 2 0 FLYWCH zinc finger domain Glyco_transf_34 PF05637.10 001318592.1_48624001_3 - 7.9e-64 215.5 0.0 1.8e-63 214.3 0.0 1.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.12 001318592.1_48624001_3 - 5.3e-05 22.8 0.0 7.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 AP2 PF00847.18 001287927.1_48622001_1 - 1.6e-12 47.4 0.1 1.6e-12 47.4 0.1 1.6 2 0 0 2 2 2 1 AP2 domain Bax1-I PF01027.18 001318623.1_48622001_1 - 2.7e-36 125.2 17.0 3.2e-36 125.0 17.0 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Phage_holin_8 PF16931.3 001318623.1_48622001_1 - 0.083 12.7 6.1 2 8.3 2.3 3.2 1 1 1 3 3 3 0 Putative phage holin adh_short_C2 PF13561.4 001318611.1_48623001_2 - 4.8e-58 196.3 0.1 6.1e-58 196.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001318611.1_48623001_2 - 8.2e-48 162.3 0.3 1e-47 162.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001318611.1_48623001_2 - 4.7e-13 49.3 0.2 7.7e-13 48.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001318611.1_48623001_2 - 0.00079 18.8 0.1 0.02 14.2 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family WD40 PF00400.30 001318557.1_48623001_2 - 6.7e-24 83.6 16.0 0.00012 22.6 0.4 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001318557.1_48623001_2 - 1.8e-11 44.1 7.8 1.4e-05 25.2 0.3 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001318557.1_48623001_2 - 0.023 14.4 0.3 0.42 10.3 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.23 001318643.1_48624001_2 - 9e-75 251.3 0.0 1.3e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001318643.1_48624001_2 - 1.3e-33 111.9 10.4 5.5e-09 34.8 0.6 4.6 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001318643.1_48624001_2 - 1.8e-27 96.1 0.0 2.9e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.4 001318643.1_48624001_2 - 2.1e-26 89.5 5.9 5.1e-07 29.0 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001318643.1_48624001_2 - 7.6e-25 87.0 6.1 4.8e-12 46.0 1.7 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001318643.1_48624001_2 - 1.2e-22 78.2 7.0 4.8e-06 25.7 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001318643.1_48624001_2 - 4.7e-22 77.4 11.1 8.4e-10 38.1 0.5 4.6 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.5 001318643.1_48624001_2 - 7.6e-08 32.1 1.1 0.012 15.4 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001318643.1_48624001_2 - 4.2e-06 26.9 0.2 0.0067 16.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.12 001318643.1_48624001_2 - 3.7e-05 23.0 0.1 7.6e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001318643.1_48624001_2 - 0.00015 21.6 0.0 0.15 11.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.7 001318643.1_48624001_2 - 0.00021 21.5 0.4 0.3 11.3 0.1 2.6 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.4 001318643.1_48624001_2 - 0.0024 17.1 0.0 0.01 15.0 0.0 2.0 2 1 0 2 2 2 1 Kinase-like EFhand_Ca_insen PF08726.8 001318643.1_48624001_2 - 0.0091 15.9 0.8 0.049 13.6 0.2 2.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand tRNA_synt_1c_R1 PF04558.13 001318643.1_48624001_2 - 0.041 13.7 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 GPHH PF16905.3 001318643.1_48624001_2 - 0.056 13.1 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 1 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_10 PF14788.4 001318643.1_48624001_2 - 0.27 11.0 3.8 6.2 6.6 0.1 3.0 3 1 0 3 3 3 0 EF hand MIOX PF05153.13 001318561.1_48622001_1 - 4.7e-107 357.1 2.1 6.1e-107 356.7 2.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.20 001318561.1_48622001_1 - 0.046 13.8 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 HD domain WRKY PF03106.13 001318664.1_48623001_1 - 1.5e-48 162.8 22.5 8.9e-26 89.9 5.9 2.4 2 0 0 2 2 2 2 WRKY DNA -binding domain FAR1 PF03101.13 001318664.1_48623001_1 - 0.03 14.9 3.5 0.86 10.3 0.0 2.5 2 0 0 2 2 2 0 FAR1 DNA-binding domain AP2 PF00847.18 001318699.1_48622001_1 - 1.1e-13 51.0 1.1 1.9e-13 50.3 1.1 1.4 1 0 0 1 1 1 1 AP2 domain Ribosomal_L7Ae PF01248.24 001318564.1_48622001_3 - 1.7e-24 85.2 0.5 3.5e-24 84.2 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.10 001318564.1_48622001_3 - 0.037 12.9 0.4 0.052 12.4 0.4 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) 14-3-3 PF00244.18 001318540.1_48622001_1 - 3.5e-100 333.9 3.1 4.2e-100 333.7 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein PhoU_div PF01865.14 001318540.1_48622001_1 - 0.0055 15.9 0.2 0.5 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function DUF47 ER_lumen_recept PF00810.16 001318650.1_48623001_2 - 6.5e-36 124.2 10.2 6.5e-36 124.2 10.2 2.2 2 0 0 2 2 2 1 ER lumen protein retaining receptor PA26 PF04636.11 001318650.1_48623001_2 - 0.011 14.5 0.9 0.016 14.0 0.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Abhydrolase_3 PF07859.11 001318680.1_48623001_1 - 1.1e-48 165.7 0.0 1.4e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.7 001318680.1_48623001_1 - 1.8e-06 27.0 0.0 9.5e-06 24.6 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.26 001318680.1_48623001_1 - 0.00015 20.7 0.0 0.0023 16.8 0.0 2.3 3 0 0 3 3 3 1 Carboxylesterase family Peptidase_S9 PF00326.19 001318680.1_48623001_1 - 0.004 16.5 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.16 001318680.1_48623001_1 - 0.0045 16.4 0.0 0.084 12.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.5 001318680.1_48623001_1 - 0.037 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme ERG4_ERG24 PF01222.15 001318695.1_48623001_1 - 4.4e-85 285.9 13.1 5.1e-85 285.7 13.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Pkinase PF00069.23 001318567.1_48623001_1 - 9.4e-72 241.4 0.0 1.2e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001318567.1_48623001_1 - 2.6e-34 118.6 0.0 3.7e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001318567.1_48623001_1 - 1.6e-05 24.2 0.3 2.4e-05 23.7 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001318567.1_48623001_1 - 2.4e-05 23.7 0.0 4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.4 001318567.1_48623001_1 - 0.091 12.2 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AP2 PF00847.18 001287965.1_48623001_2 - 2.5e-13 49.9 0.1 2.5e-13 49.9 0.1 1.8 2 0 0 2 2 2 1 AP2 domain Cupin_1 PF00190.20 001318662.1_48622001_1 - 9.6e-50 168.0 1.4 1.2e-49 167.6 1.4 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.9 001318662.1_48622001_1 - 5.1e-08 32.4 0.0 1.5e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Cupin domain S4 PF01479.23 001318662.1_48622001_1 - 0.13 11.9 0.4 3.4 7.3 0.2 2.4 2 0 0 2 2 2 0 S4 domain NAP PF00956.16 001318571.1_48622001_3 - 8.2e-41 139.8 14.3 2.9e-34 118.3 5.2 2.3 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) SecA_SW PF07516.11 001318571.1_48622001_3 - 0.0026 17.7 0.0 0.0032 17.4 0.0 1.3 1 1 0 1 1 1 1 SecA Wing and Scaffold domain OmpH PF03938.12 001318571.1_48622001_3 - 0.005 16.7 2.3 0.005 16.7 2.3 1.7 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) VD10_N PF08476.8 001318571.1_48622001_3 - 0.0056 16.2 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Viral D10 N-terminal APOBEC_N PF08210.9 001318571.1_48622001_3 - 0.081 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF4065 PF13274.4 001318571.1_48622001_3 - 7.5 7.4 9.9 8.8 7.1 3.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) DUF568 PF04526.11 001318663.1_48623001_3 - 7.8e-23 81.0 0.0 1.4e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF568) Cytochrom_B561 PF03188.14 001318663.1_48623001_3 - 5.2e-07 29.7 2.6 5.2e-07 29.7 2.6 2.2 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF3087 PF11286.6 001318663.1_48623001_3 - 0.15 11.4 1.2 7.8 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) ATP-sulfurylase PF01747.15 001318620.1_48624001_3 - 9.9e-65 217.9 0.0 1.3e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.4 001318620.1_48624001_3 - 4e-46 156.4 0.0 7.3e-46 155.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain p450 PF00067.20 001318696.1_48624001_2 - 3.2e-79 266.7 0.1 4.3e-79 266.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 REF PF05755.10 001318696.1_48624001_2 - 0.081 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) RPE65 PF03055.13 001288174.1_48625001_3 - 3.4e-102 342.6 0.0 4.3e-102 342.3 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein WRKY PF03106.13 001318587.1_48624001_1 - 3.1e-51 171.4 14.0 8e-26 90.0 3.3 2.4 2 0 0 2 2 2 2 WRKY DNA -binding domain FAR1 PF03101.13 001318587.1_48624001_1 - 0.018 15.6 1.1 0.65 10.6 0.0 2.6 2 0 0 2 2 2 0 FAR1 DNA-binding domain FLYWCH PF04500.14 001318587.1_48624001_1 - 5.6 7.0 8.3 1.9 8.6 0.6 2.7 2 1 0 2 2 2 0 FLYWCH zinc finger domain Epimerase PF01370.19 001318556.1_48623001_1 - 1.3e-05 24.6 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LRR_8 PF13855.4 001318548.1_48622001_1 - 5e-15 54.9 30.6 2.2e-08 33.6 7.0 3.0 2 1 2 4 4 4 3 Leucine rich repeat LRRNT_2 PF08263.10 001318548.1_48622001_1 - 1.5e-12 47.4 0.8 3e-12 46.5 0.8 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001318548.1_48622001_1 - 8.3e-11 41.8 23.2 1e-05 25.6 4.7 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001318548.1_48622001_1 - 1.6e-06 27.6 10.1 0.86 10.2 0.2 5.4 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.4 001318548.1_48622001_1 - 1.7 8.8 14.2 8.4 6.6 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich repeat AP2 PF00847.18 001318631.1_48622001_1 - 2.1e-13 50.2 0.1 2.1e-13 50.2 0.1 1.6 2 0 0 2 2 2 1 AP2 domain BES1_N PF05687.11 001318631.1_48622001_1 - 0.15 12.3 7.8 0.3 11.4 2.2 2.2 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal Myb_DNA-binding PF00249.29 001318667.1_48622001_1 - 1.5e-08 34.5 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sugar_tr PF00083.22 001288271.1_48624001_2 - 1.4e-46 159.2 20.8 2e-46 158.6 20.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001288271.1_48624001_2 - 3.1e-22 78.9 29.0 4e-21 75.2 30.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MIP PF00230.18 001318604.1_48623001_1 - 1.5e-82 276.6 11.1 1.8e-82 276.3 11.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein TAXi_C PF14541.4 001318641.1_48623001_1 - 1.1e-49 168.1 0.0 2.3e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.4 001318641.1_48623001_1 - 9.9e-32 110.5 2.1 1.5e-31 109.9 2.1 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.21 001318641.1_48623001_1 - 0.0098 15.2 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease CAP PF00188.24 001288166.1_48622001_3 - 1.6e-20 74.1 5.1 2.5e-20 73.4 5.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_transf_43 PF03360.14 001318554.1_48624001_3 - 1.6e-58 197.8 0.2 2.3e-58 197.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 DUF4127 PF13552.4 001318554.1_48624001_3 - 0.028 12.9 0.0 0.042 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) WRKY PF03106.13 001318606.1_48625001_1 - 9.1e-51 169.9 17.1 2.9e-25 88.2 4.4 2.4 2 0 0 2 2 2 2 WRKY DNA -binding domain FAR1 PF03101.13 001318606.1_48625001_1 - 0.071 13.7 1.0 0.75 10.4 0.1 2.4 2 0 0 2 2 2 0 FAR1 DNA-binding domain KNOX2 PF03791.11 001318675.1_48623001_2 - 2.6e-23 81.3 7.1 3.8e-23 80.8 3.7 2.3 2 0 0 2 2 2 1 KNOX2 domain KNOX1 PF03790.11 001318675.1_48623001_2 - 1.3e-20 72.7 0.1 2.6e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 KNOX1 domain Homeobox_KN PF05920.9 001318675.1_48623001_2 - 4.9e-17 61.4 1.5 1e-16 60.4 1.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain ELK PF03789.11 001318675.1_48623001_2 - 8.5e-11 41.5 5.7 2.5e-10 40.0 5.1 2.1 2 0 0 2 2 2 1 ELK domain Homeobox PF00046.27 001318675.1_48623001_2 - 2.2e-07 30.4 1.3 7.2e-07 28.8 1.3 1.9 1 0 0 1 1 1 1 Homeobox domain TIM PF00121.16 001318582.1_48622001_1 - 6.4e-89 297.4 0.0 7.5e-89 297.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase RRM_1 PF00076.20 001318661.1_48623001_3 - 9.8e-28 95.7 0.0 1e-10 41.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.4 001318661.1_48623001_3 - 0.013 15.6 0.0 3 7.9 0.0 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.9 001318661.1_48623001_3 - 0.021 14.8 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Na_Ca_ex PF01699.22 001318574.1_48624001_1 - 1e-52 178.0 30.4 2.8e-28 98.7 7.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein 3Beta_HSD PF01073.17 001318565.1_48624001_1 - 4.7e-86 288.1 0.0 8.5e-86 287.3 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.19 001318565.1_48624001_1 - 9.2e-32 110.3 0.0 1.6e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4499 PF14934.4 001318565.1_48624001_1 - 6.2e-26 90.5 3.9 1.6e-25 89.1 3.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) GDP_Man_Dehyd PF16363.3 001318565.1_48624001_1 - 1.6e-20 73.6 0.0 2.1e-19 69.9 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 001318565.1_48624001_1 - 1.3e-11 44.6 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.13 001318565.1_48624001_1 - 1.9e-10 40.2 0.0 4.2e-10 39.1 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001318565.1_48624001_1 - 5.2e-10 38.8 0.0 7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.10 001318565.1_48624001_1 - 7.2e-09 35.0 0.1 2.9e-07 29.8 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.11 001318565.1_48624001_1 - 1.4e-08 34.4 0.0 2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.8 001318565.1_48624001_1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.23 001318565.1_48624001_1 - 2e-05 24.0 0.0 5.3e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase FtsJ PF01728.17 001318565.1_48624001_1 - 0.073 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Kunitz_legume PF00197.16 001318694.1_48622001_1 - 3.7e-35 121.3 0.0 4.4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor DUF4752 PF15944.3 001318628.1_48623001_1 - 0.86 9.6 5.1 1.8 8.5 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) OAD_gamma PF04277.11 001318628.1_48623001_1 - 4.7 7.7 10.2 15 6.1 10.2 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AP2 PF00847.18 001318628.1_48623001_3 - 5.5e-14 52.0 2.3 5.5e-14 52.0 2.3 2.0 2 0 0 2 2 2 1 AP2 domain AMPK1_CBM PF16561.3 001318586.1_48623001_3 - 1.1e-20 73.5 0.1 1.9e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DSPc PF00782.18 001318586.1_48623001_3 - 2e-13 50.2 0.0 5.2e-13 48.8 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.10 001318586.1_48623001_3 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) CBM_48 PF02922.16 001318586.1_48623001_3 - 0.0084 16.3 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_transf_8 PF01501.18 001318597.1_48623001_3 - 2.3e-37 128.8 0.0 3e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 FA_desaturase_2 PF03405.12 001318673.1_48623001_1 - 1.8e-160 533.0 0.0 2.1e-160 532.8 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.15 001318673.1_48623001_1 - 0.0058 16.9 0.0 0.53 10.5 0.1 2.4 2 0 0 2 2 2 2 Rubrerythrin Chloroa_b-bind PF00504.19 001318625.1_48622001_1 - 9.6e-51 172.4 0.0 1.4e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PhosphMutase PF10143.7 001318625.1_48622001_1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Ribosomal_S7 PF00177.19 001318648.1_48622001_1 - 2.1e-37 127.9 1.8 2.8e-37 127.5 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Pro_isomerase PF00160.19 001318601.1_48623001_1 - 2.1e-43 148.2 0.1 3.3e-43 147.5 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GST_N PF02798.18 001318652.1_48622001_1 - 2.9e-20 72.3 0.3 4.6e-20 71.6 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001318652.1_48622001_1 - 2.9e-18 65.9 0.0 5.2e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001318652.1_48622001_1 - 3.4e-15 55.9 0.2 6e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001318652.1_48622001_1 - 6.5e-14 51.9 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001318652.1_48622001_1 - 5.5e-05 23.2 0.0 9.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 001318652.1_48622001_1 - 0.00059 20.4 0.0 0.0021 18.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.4 001318652.1_48622001_1 - 0.0023 17.7 0.1 0.004 16.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.23 001318629.1_48623001_1 - 3e-66 223.4 0.0 3.5e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001318629.1_48623001_1 - 4.5e-38 130.9 0.0 5.7e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001318629.1_48623001_1 - 0.00012 21.3 0.2 0.00095 18.4 0.1 2.3 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.9 001318629.1_48623001_1 - 0.011 14.7 0.1 0.035 13.0 0.1 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.21 001318629.1_48623001_1 - 0.023 14.5 0.2 0.14 11.9 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pyrophosphatase PF00719.17 001318584.1_48623001_1 - 3e-52 176.5 0.3 3.9e-52 176.2 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase WRKY PF03106.13 001318697.1_48624001_2 - 4.8e-27 94.0 2.9 9.8e-27 93.0 2.9 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain SYCE1 PF15233.4 001318697.1_48624001_2 - 0.074 13.0 4.8 0.13 12.2 4.8 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 IncA PF04156.12 001318697.1_48624001_2 - 7.3 6.2 8.1 0.12 12.0 1.0 1.6 2 0 0 2 2 2 0 IncA protein DUF3285 PF11688.6 001318697.1_48624001_3 - 0.064 13.0 0.7 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) RWD PF05773.20 001318653.1_48623001_3 - 9.7e-21 74.1 0.8 1.8e-20 73.2 0.8 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.3 001318653.1_48623001_3 - 0.0059 16.9 1.7 0.0059 16.9 1.7 2.3 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 PBP1_TM PF14812.4 001318653.1_48623001_3 - 1.1 9.6 8.1 0.29 11.5 3.6 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.8 001318653.1_48623001_3 - 1.4 9.2 11.8 24 5.3 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glyco_transf_8 PF01501.18 001318596.1_48623001_1 - 3.1e-39 135.0 0.0 3.8e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.6 001318596.1_48623001_1 - 0.012 14.8 0.0 0.037 13.2 0.0 1.7 2 0 0 2 2 2 0 Mannosyltransferase putative HMA PF00403.24 001318596.1_48623001_1 - 0.077 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Heavy-metal-associated domain WD40 PF00400.30 001318703.1_48623001_2 - 1.6e-46 155.2 30.9 1.4e-07 32.0 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001318703.1_48623001_2 - 5.3e-11 42.5 1.9 0.26 11.5 0.0 5.0 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001318703.1_48623001_2 - 2.6e-05 24.0 0.2 0.00026 20.8 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001318703.1_48623001_2 - 0.00013 20.9 0.6 3.7 6.3 0.0 4.3 1 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.14 001318703.1_48623001_2 - 0.0073 14.8 0.2 0.57 8.5 0.2 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain KNOX2 PF03791.11 001318665.1_48623001_1 - 2.2e-18 65.5 1.0 6.1e-18 64.1 1.0 1.8 1 0 0 1 1 1 1 KNOX2 domain Homeobox_KN PF05920.9 001318665.1_48623001_1 - 5.4e-17 61.3 3.2 1.4e-16 60.0 3.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain KNOX1 PF03790.11 001318665.1_48623001_1 - 5.6e-17 61.1 0.6 1e-16 60.3 0.6 1.4 1 0 0 1 1 1 1 KNOX1 domain Homeobox PF00046.27 001318665.1_48623001_1 - 0.0012 18.4 1.1 0.0012 18.4 1.1 2.2 2 0 0 2 2 2 1 Homeobox domain ELK PF03789.11 001318665.1_48623001_1 - 0.0013 18.6 2.3 0.0023 17.8 0.2 2.4 2 0 0 2 2 2 1 ELK domain PP2C PF00481.19 001318660.1_48623001_1 - 1.1e-61 208.6 0.0 1.4e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001318660.1_48623001_1 - 0.00056 19.5 0.0 0.0016 18.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C CAMSAP_CH PF11971.6 001318614.1_48624001_2 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain KNOX2 PF03791.11 001318614.1_48624001_3 - 2.1e-18 65.6 0.6 2.1e-18 65.6 0.6 2.1 2 0 0 2 2 2 1 KNOX2 domain Homeobox_KN PF05920.9 001318614.1_48624001_3 - 8.6e-18 63.8 3.2 1.9e-17 62.7 3.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain KNOX1 PF03790.11 001318614.1_48624001_3 - 3.4e-17 61.8 0.6 6.1e-17 61.0 0.6 1.4 1 0 0 1 1 1 1 KNOX1 domain ELK PF03789.11 001318614.1_48624001_3 - 6.9e-07 29.0 0.5 1.5e-06 27.9 0.5 1.6 1 0 0 1 1 1 1 ELK domain Homeobox PF00046.27 001318614.1_48624001_3 - 1.6e-05 24.4 1.1 5.5e-05 22.8 1.1 1.9 1 0 0 1 1 1 1 Homeobox domain Ras PF00071.20 001318677.1_48622001_2 - 1.6e-65 219.5 0.4 2.1e-65 219.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001318677.1_48622001_2 - 8.4e-37 125.9 0.1 1.4e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001318677.1_48622001_2 - 2.2e-16 59.7 0.1 2.8e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001318677.1_48622001_2 - 1.1e-06 28.0 0.1 1.7e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.14 001318677.1_48622001_2 - 1.2e-05 25.1 0.2 0.14 11.9 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001318677.1_48622001_2 - 2.1e-05 23.9 0.1 2.6e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001318677.1_48622001_2 - 4.7e-05 22.9 0.2 0.00011 21.6 0.1 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001318677.1_48622001_2 - 6.4e-05 22.9 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.27 001318677.1_48622001_2 - 0.0044 17.3 0.0 0.94 9.8 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.16 001318677.1_48622001_2 - 0.019 14.4 0.0 0.09 12.2 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.4 001318677.1_48622001_2 - 0.035 14.4 0.0 0.049 13.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.4 001318677.1_48622001_2 - 0.045 13.9 0.0 0.067 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.12 001318677.1_48622001_2 - 0.061 13.2 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.16 001318677.1_48622001_2 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_29 PF13555.4 001318677.1_48622001_2 - 0.092 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.25 001318677.1_48622001_2 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter LANC_like PF05147.11 001318677.1_48622001_2 - 0.12 10.8 0.0 0.26 9.7 0.0 1.4 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein SCAI PF12070.6 001318657.1_48625001_3 - 5.8e-195 649.0 0.0 7.1e-195 648.7 0.0 1.0 1 0 0 1 1 1 1 Protein SCAI NAM PF02365.13 001318666.1_48623001_1 - 2.7e-27 95.3 0.3 7.7e-27 93.8 0.1 1.8 2 0 0 2 2 2 1 No apical meristem (NAM) protein Terpene_synth_C PF03936.14 001318658.1_48625001_1 - 5.5e-58 196.3 0.2 1e-57 195.4 0.2 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001318658.1_48625001_1 - 6e-40 136.9 2.8 1.1e-39 135.9 2.8 1.4 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain SQHop_cyclase_C PF13243.4 001318658.1_48625001_1 - 0.011 14.8 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Baculo_PEP_N PF04512.10 001318658.1_48625001_1 - 0.013 15.6 0.7 0.094 12.9 0.1 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, N terminus Prenyltrans PF00432.19 001318658.1_48625001_1 - 0.15 11.7 0.2 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Gln-synt_C PF00120.22 001318646.1_48623001_3 - 1.1e-15 57.4 0.0 2.1e-14 53.1 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001318646.1_48623001_3 - 8.1e-10 38.2 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain CbiA PF01656.21 001318605.1_48623001_2 - 3.3e-24 85.2 0.0 4.9e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.7 001318605.1_48623001_2 - 4.1e-19 68.9 0.8 2.7e-18 66.2 0.8 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.4 001318605.1_48623001_2 - 2.2e-15 56.9 0.0 4.7e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.16 001318605.1_48623001_2 - 4.1e-10 39.4 0.0 5.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.9 001318605.1_48623001_2 - 3.4e-07 29.7 1.0 3.9e-06 26.2 1.0 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.13 001318605.1_48623001_2 - 5.6e-07 29.0 2.6 2.5e-05 23.6 0.9 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase CBP_BcsQ PF06564.10 001318605.1_48623001_2 - 4.3e-05 23.0 0.6 0.015 14.7 0.5 2.2 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.4 001318605.1_48623001_2 - 0.023 14.2 0.3 0.053 13.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.3 001318605.1_48623001_2 - 0.089 12.5 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.4 001318605.1_48623001_2 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.4 001318605.1_48623001_2 - 0.18 11.4 1.7 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.20 001318605.1_48623001_2 - 0.21 11.1 0.3 0.46 10.0 0.3 1.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Aldo_ket_red PF00248.19 001318603.1_48623001_2 - 1.4e-69 234.3 0.0 1.6e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CS PF04969.14 001318634.1_48623001_1 - 2.1e-09 38.1 0.0 3.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.10 001318634.1_48623001_1 - 0.25 11.8 26.4 0.41 11.1 26.4 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region zf-Dof PF02701.13 001318682.1_48623001_1 - 2.3e-32 110.8 10.0 4.2e-32 110.0 10.0 1.4 1 0 0 1 1 1 1 Dof domain, zinc finger PHD PF00628.27 001318682.1_48623001_1 - 0.027 14.2 2.5 0.056 13.2 2.5 1.5 1 0 0 1 1 1 0 PHD-finger Lar_restr_allev PF14354.4 001318682.1_48623001_1 - 0.068 13.4 1.1 0.18 12.1 1.1 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-RING_7 PF02591.13 001318682.1_48623001_1 - 0.14 12.3 2.8 0.74 9.9 0.1 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain Ribosomal_S8 PF00410.17 001288207.1_48622001_3 - 1.2e-21 76.8 0.1 2.2e-21 76.0 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 GRAS PF03514.12 001318585.1_48625001_3 - 4.5e-135 450.3 0.0 5.9e-135 449.9 0.0 1.2 1 0 0 1 1 1 1 GRAS domain family DELLA PF12041.6 001318585.1_48625001_3 - 4.3e-34 116.1 0.6 1.4e-33 114.4 0.6 2.0 1 0 0 1 1 1 1 Transcriptional regulator DELLA protein N terminal Tmemb_cc2 PF10267.7 001318585.1_48625001_3 - 0.15 11.0 1.2 0.24 10.4 1.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein XPC-binding PF09280.9 001318585.1_48625001_3 - 0.47 10.1 2.4 1.8 8.3 0.0 2.8 2 1 0 2 2 2 0 XPC-binding domain SHMT PF00464.17 001308514.1_53724001_2 - 6.4e-211 699.9 0.0 7.7e-211 699.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.19 001308514.1_53724001_2 - 0.066 12.2 0.0 0.18 10.8 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II Pkinase PF00069.23 001316037.1_06923001_1 - 4.3e-76 255.6 0.0 1.8e-75 253.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001316037.1_06923001_1 - 8.4e-37 126.7 0.0 1.3e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.12 001316037.1_06923001_1 - 1.6e-19 69.7 1.0 3.4e-19 68.6 1.0 1.6 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.4 001316037.1_06923001_1 - 7.3e-08 31.9 0.0 2.2e-06 27.1 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.20 001316037.1_06923001_1 - 0.00077 19.0 0.9 0.0064 16.0 0.0 2.6 2 1 1 3 3 3 1 RIO1 family APH PF01636.21 001316037.1_06923001_1 - 0.0025 17.7 1.4 0.015 15.1 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.12 001316037.1_06923001_1 - 0.0035 16.6 0.0 0.0072 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.14 001316037.1_06923001_1 - 0.0076 16.3 0.1 0.026 14.5 0.1 1.9 1 0 0 1 1 1 1 ABC1 family EndoU_bacteria PF14436.4 001316037.1_06923001_1 - 0.057 13.6 0.4 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial EndoU nuclease Kunitz_legume PF00197.16 001288172.1_48622001_2 - 3.1e-36 124.8 0.0 3.9e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin and protease inhibitor TPT PF03151.14 001315982.1_06923001_1 - 1.7e-124 414.8 25.6 2e-124 414.6 25.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.18 001315982.1_06923001_1 - 1.2e-15 57.8 25.7 3.3e-10 40.1 13.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF676 PF05057.12 001315982.1_06923001_1 - 0.018 14.4 1.9 2.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) UAA PF08449.9 001315982.1_06923001_1 - 0.65 9.0 21.7 1.3 8.0 21.7 1.4 1 1 0 1 1 1 0 UAA transporter family Glutaredoxin PF00462.22 001288007.1_48622001_1 - 5.9e-21 74.3 0.0 9.7e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.12 001288007.1_48622001_1 - 0.02 15.1 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.22 001288079.1_48622001_3 - 3.3e-11 43.1 0.0 4.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin RNA_pol_Rpb5_C PF01191.17 001315912.1_06922001_3 - 8.9e-26 89.3 0.2 1.4e-25 88.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.12 001315912.1_06922001_3 - 7.3e-22 77.6 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain NAD_binding_6 PF08030.10 001315912.1_06922001_3 - 0.048 13.7 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain AP2 PF00847.18 001315935.1_06922001_1 - 5.5e-10 39.2 2.6 7.3e-10 38.8 0.1 2.1 2 0 0 2 2 2 1 AP2 domain IF4E PF01652.16 001315935.1_06922001_1 - 0.019 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E DUF1674 PF07896.10 001149693.1_53722001_3 - 7.3e-18 64.7 3.8 1.7e-17 63.5 3.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) DUF2371 PF10177.7 001154297.1_53723001_2 - 0.16 12.0 0.1 0.26 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Sporozoite_P67 PF05642.9 001154297.1_53723001_2 - 0.84 7.5 10.7 0.9 7.4 10.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-RING_2 PF13639.4 001154297.1_53723001_3 - 9.2e-13 48.1 3.5 1.6e-12 47.3 3.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.4 001154297.1_53723001_3 - 5.9e-09 35.5 2.3 1e-08 34.7 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001154297.1_53723001_3 - 5.2e-08 32.9 4.0 1.2e-07 31.7 4.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001154297.1_53723001_3 - 5.5e-08 32.3 0.4 1.1e-07 31.3 0.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.23 001154297.1_53723001_3 - 9.5e-08 31.7 1.4 1.9e-07 30.7 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001154297.1_53723001_3 - 1.9e-07 30.7 1.7 3.5e-07 29.8 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001154297.1_53723001_3 - 2e-06 27.6 3.0 4.1e-06 26.6 3.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001154297.1_53723001_3 - 2e-06 27.5 1.5 3.5e-06 26.7 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.4 001154297.1_53723001_3 - 3e-05 23.6 3.5 5.5e-05 22.8 3.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.3 001154297.1_53723001_3 - 0.00027 20.3 2.0 0.00053 19.4 2.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.5 001154297.1_53723001_3 - 0.00084 19.2 2.9 0.0023 17.8 2.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.6 001154297.1_53723001_3 - 0.0032 17.5 3.0 0.011 15.7 3.0 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.5 001154297.1_53723001_3 - 0.021 14.8 3.0 0.044 13.8 3.0 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.4 001154297.1_53723001_3 - 0.052 13.4 0.6 0.51 10.2 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.6 001154297.1_53723001_3 - 0.14 11.9 0.4 0.27 11.0 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.4 001154297.1_53723001_3 - 0.14 12.2 2.2 0.34 11.0 2.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.4 001154297.1_53723001_3 - 2.9 7.5 6.0 0.25 11.0 1.3 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LRR_8 PF13855.4 001155165.1_53724001_2 - 2.9e-06 26.8 8.7 0.017 14.7 0.4 3.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 001155165.1_53724001_2 - 0.058 13.7 12.7 2.2 8.7 2.7 4.5 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001155165.1_53724001_2 - 0.063 13.6 9.7 20 6.1 0.1 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat 2-oxoacid_dh PF00198.21 001318595.1_48624001_1 - 1.5e-77 260.1 0.0 2.7e-77 259.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.20 001318595.1_48624001_1 - 6.6e-18 64.2 0.1 1.3e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.15 001318595.1_48624001_1 - 8.1e-14 51.5 0.1 1.9e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.4 001318595.1_48624001_1 - 0.011 15.4 0.2 0.61 9.8 0.1 2.7 1 1 1 2 2 2 0 Biotin-lipoyl like FAM91_C PF14648.4 001153164.2_53724001_3 - 4e-47 160.9 0.1 6.5e-34 117.3 0.0 3.0 2 1 1 3 3 3 3 FAM91 C-terminus p450 PF00067.20 001318685.1_48624001_2 - 1e-106 357.3 0.0 1.3e-106 357.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Actin_micro PF17003.3 001318685.1_48624001_2 - 0.024 13.7 0.1 0.036 13.1 0.1 1.1 1 0 0 1 1 1 0 Putative actin-like family DNA_pol_A_exo1 PF01612.18 001288525.1_48623001_3 - 1.1e-24 87.0 0.0 1.4e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease KH_1 PF00013.27 001288525.1_48623001_3 - 1.1e-09 37.9 0.4 3e-09 36.4 0.3 1.8 2 0 0 2 2 2 1 KH domain KH_4 PF13083.4 001288525.1_48623001_3 - 0.0004 20.1 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_2 PF07650.15 001288525.1_48623001_3 - 0.071 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 KH domain DCP1 PF06058.11 001288526.1_48623001_2 - 5.8e-45 151.9 0.3 8.7e-45 151.3 0.3 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family NAM PF02365.13 001288073.1_48623001_1 - 3.4e-28 98.2 0.7 1.1e-27 96.6 0.3 1.9 2 0 0 2 2 2 1 No apical meristem (NAM) protein Longin PF13774.4 001288299.1_48623001_3 - 7.4e-25 86.7 0.2 1.3e-24 85.9 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.19 001288299.1_48623001_3 - 1e-17 63.6 0.5 1.9e-17 62.7 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin SRF-TF PF00319.16 001287825.1_48622001_1 - 2.3e-24 84.4 0.1 4.8e-24 83.4 0.1 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001287825.1_48622001_1 - 1.4e-13 50.7 10.8 2.4e-13 50.0 10.3 1.7 1 1 0 1 1 1 1 K-box region TSC22 PF01166.16 001287825.1_48622001_1 - 0.034 14.3 0.8 0.13 12.4 0.8 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family Mnd1 PF03962.13 001287825.1_48622001_1 - 2 8.1 11.2 4 7.1 11.2 1.5 1 1 0 1 1 1 0 Mnd1 family Pkinase PF00069.23 001288527.1_48625001_3 - 5e-74 248.8 0.0 7e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001288527.1_48625001_3 - 1.9e-33 111.3 5.9 4.7e-09 35.0 0.1 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001288527.1_48625001_3 - 4.5e-32 111.2 0.0 6.4e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001288527.1_48625001_3 - 1.6e-28 98.8 3.0 2.5e-14 53.4 2.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001288527.1_48625001_3 - 4.1e-23 79.2 5.2 5.5e-07 28.9 0.3 4.7 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001288527.1_48625001_3 - 6e-22 76.0 4.8 3.9e-05 22.8 0.4 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001288527.1_48625001_3 - 5.5e-19 67.6 5.4 4.2e-10 39.1 0.5 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.5 001288527.1_48625001_3 - 1.9e-08 34.0 0.2 0.003 17.4 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001288527.1_48625001_3 - 2.2e-07 31.1 0.2 0.0023 18.1 0.3 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.4 001288527.1_48625001_3 - 3.1e-05 23.3 0.0 0.0025 17.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like EF-hand_11 PF08976.9 001288527.1_48625001_3 - 4.7e-05 24.1 0.1 0.13 13.0 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain Kdo PF06293.12 001288527.1_48625001_3 - 0.00016 20.9 0.0 0.00034 19.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.4 001288527.1_48625001_3 - 0.00032 20.8 0.1 0.69 10.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain APH PF01636.21 001288527.1_48625001_3 - 0.041 13.7 0.0 4.1 7.1 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF4590 PF15257.4 001288527.1_48625001_3 - 0.12 12.2 0.1 4.2 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4590) Trypan_PARP PF05887.9 001288527.1_48625001_3 - 1.6 8.7 11.6 2.4 8.1 11.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_S19e PF01090.17 001288300.1_48622001_2 - 1.8e-57 192.7 0.0 2.2e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Ferritin PF00210.22 001288074.1_48622001_1 - 9.2e-33 113.0 7.1 1.2e-32 112.7 7.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.15 001288074.1_48622001_1 - 0.017 15.4 3.8 0.036 14.3 3.8 1.8 1 1 0 1 1 1 0 Rubrerythrin COQ7 PF03232.11 001288074.1_48622001_1 - 0.033 13.8 0.3 0.081 12.6 0.1 1.6 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 HATPase_c PF02518.24 001287828.1_48625001_3 - 9.8e-34 116.1 0.0 1.8e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.23 001287828.1_48625001_3 - 6e-16 58.1 0.9 6e-16 58.1 0.9 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF PF01590.24 001287828.1_48625001_3 - 4e-15 56.4 0.1 9.3e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.4 001287828.1_48625001_3 - 0.016 15.4 0.0 6.5 7.0 0.0 2.5 2 0 0 2 2 2 0 GAF domain HATPase_c_3 PF13589.4 001287828.1_48625001_3 - 0.051 13.3 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.23 001288301.1_48624001_1 - 2.1e-73 246.8 0.0 3e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001288301.1_48624001_1 - 3.8e-33 110.4 9.0 1.4e-08 33.6 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001288301.1_48624001_1 - 7.7e-26 87.7 5.0 2.5e-07 30.0 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001288301.1_48624001_1 - 1.4e-25 89.5 4.2 8e-12 45.3 2.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.15 001288301.1_48624001_1 - 3.8e-25 88.5 0.0 6.2e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_5 PF13202.4 001288301.1_48624001_1 - 3.5e-23 79.9 6.4 7.9e-06 25.0 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001288301.1_48624001_1 - 3.7e-21 74.5 10.6 4.6e-09 35.8 0.0 4.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.5 001288301.1_48624001_1 - 4.5e-08 32.8 2.5 0.015 15.1 0.2 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001288301.1_48624001_1 - 1.5e-05 25.1 0.3 0.015 15.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.12 001288301.1_48624001_1 - 0.00019 20.7 0.1 0.00039 19.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.7 001288301.1_48624001_1 - 0.00021 21.5 0.4 0.78 9.9 0.1 2.6 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.21 001288301.1_48624001_1 - 0.00076 19.3 0.0 1.1 9.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family EFhand_Ca_insen PF08726.8 001288301.1_48624001_1 - 0.018 15.0 0.4 0.15 12.0 0.2 2.5 2 0 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_10 PF14788.4 001288301.1_48624001_1 - 0.029 14.1 0.2 2.3 8.0 0.0 2.9 2 1 0 2 2 2 0 EF hand tRNA_synt_1c_R1 PF04558.13 001288301.1_48624001_1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Caleosin PF05042.11 001288301.1_48624001_1 - 0.14 11.9 0.4 19 5.0 0.1 2.9 2 1 1 3 3 3 0 Caleosin related protein CS PF04969.14 001288529.1_48623001_2 - 9.4e-18 64.9 0.0 2.1e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 CS domain Bap31 PF05529.10 001288529.1_48623001_2 - 1.8 8.0 4.4 3.5 7.0 4.4 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF588 PF04535.10 001288530.1_48622001_1 - 2.2e-26 92.3 15.0 2.8e-26 92.0 15.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF588) Ribosomal_L14e PF01929.15 001288076.1_48622001_1 - 3.6e-26 91.3 4.7 6e-26 90.6 4.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.27 001288076.1_48622001_1 - 0.089 12.7 0.8 0.16 11.9 0.8 1.4 1 0 0 1 1 1 0 KOW motif adh_short PF00106.23 001287833.1_48623001_1 - 9.7e-51 171.9 0.0 1.2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001287833.1_48623001_1 - 3e-47 161.0 0.0 3.6e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001287833.1_48623001_1 - 1.6e-08 34.6 0.1 2.5e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001287833.1_48623001_1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.8 001287833.1_48623001_1 - 0.027 13.7 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.18 001287833.1_48623001_1 - 0.034 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cytokin-bind PF09265.8 001288077.1_48624001_1 - 1.1e-110 369.3 0.1 1.6e-110 368.8 0.1 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 001288077.1_48624001_1 - 9.7e-19 67.3 0.5 1.5e-18 66.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Myb_DNA-binding PF00249.29 001288078.1_48623001_3 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain NAM PF02365.13 001287836.1_48624001_1 - 6.5e-27 94.1 0.1 1.4e-26 93.0 0.1 1.6 1 0 0 1 1 1 1 No apical meristem (NAM) protein Ribosomal_L18A PF01775.15 001288305.1_48622001_1 - 6.8e-53 177.8 4.1 9.8e-53 177.3 4.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Sod_Cu PF00080.18 001288080.1_48621001_3 - 3.8e-48 163.1 4.3 4.7e-48 162.8 4.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) S4 PF01479.23 001288306.1_48622001_1 - 6.1e-11 41.7 1.4 1.4e-10 40.6 1.4 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.17 001288306.1_48622001_1 - 1.9e-07 31.8 1.2 5.9e-07 30.2 1.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Epimerase PF01370.19 001288307.1_48623001_1 - 3e-28 98.8 0.0 4.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001288307.1_48623001_1 - 2.9e-25 88.7 0.0 3.8e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.3 001288307.1_48623001_1 - 2.5e-16 59.8 0.0 4.6e-16 59.0 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 001288307.1_48623001_1 - 2.1e-14 53.7 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001288307.1_48623001_1 - 8.7e-11 41.3 0.0 4.7e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.11 001288307.1_48623001_1 - 2.2e-09 37.1 0.0 3.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.13 001288307.1_48623001_1 - 5.9e-08 32.1 0.0 8.3e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.8 001288307.1_48623001_1 - 5e-06 26.4 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.23 001288307.1_48623001_1 - 0.00011 21.5 0.3 0.00079 18.8 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase RmlD_sub_bind PF04321.15 001288307.1_48623001_1 - 0.044 12.7 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 2OG-FeII_Oxy PF03171.18 001288082.1_48623001_1 - 7.6e-23 80.8 0.0 2.9e-22 78.9 0.0 2.0 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001288082.1_48623001_1 - 9.4e-14 52.1 0.0 1.7e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ribosomal_60s PF00428.17 001288083.1_48623001_1 - 5.7e-23 81.2 7.6 1.7e-22 79.6 7.6 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.18 001288083.1_48623001_1 - 4.4e-20 71.5 0.4 9.2e-20 70.5 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 MMPL PF03176.13 001288083.1_48623001_1 - 0.065 12.0 0.4 0.1 11.4 0.4 1.2 1 0 0 1 1 1 0 MMPL family Metallophos PF00149.26 001288309.1_48626001_1 - 6.6e-34 118.1 0.1 1.1e-33 117.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_4 PF13418.4 001288309.1_48626001_1 - 3.9e-23 81.0 8.9 3.7e-06 26.7 0.0 6.9 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.4 001288309.1_48626001_1 - 3.6e-19 68.4 10.8 7e-05 22.9 0.0 7.6 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.4 001288309.1_48626001_1 - 2e-17 62.6 5.2 0.0037 17.1 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.23 001288309.1_48626001_1 - 4.6e-17 61.2 1.4 0.00094 18.6 0.2 6.7 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.13 001288309.1_48626001_1 - 8.8e-17 60.2 2.7 3.3e-05 23.6 0.0 6.3 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.4 001288309.1_48626001_1 - 3.5e-11 42.8 1.9 0.078 13.2 0.1 6.1 5 1 1 6 6 6 3 Kelch motif STPPase_N PF16891.3 001288309.1_48626001_1 - 3.8e-05 23.9 0.0 6.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glycolytic PF00274.17 001287840.1_48623001_1 - 1.8e-142 474.1 0.0 2.3e-142 473.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.17 001287840.1_48623001_2 - 4e-24 84.9 1.5 5e-24 84.6 1.5 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Ribosomal_L23 PF00276.18 001288535.1_48622001_2 - 3e-15 56.2 0.0 6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 EF-hand_7 PF13499.4 001288310.1_48623001_2 - 2.7e-10 40.5 0.0 4.9e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001288310.1_48623001_2 - 1.6e-07 30.3 2.6 0.0018 17.5 0.1 4.6 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.4 001288310.1_48623001_2 - 5.3e-07 28.9 0.8 0.0046 16.7 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.4 001288310.1_48623001_2 - 0.00023 20.4 0.2 0.00023 20.4 0.2 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.4 001288310.1_48623001_2 - 0.015 14.9 3.7 0.26 10.9 0.1 3.7 4 0 0 4 4 4 0 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001288310.1_48623001_2 - 0.02 15.1 0.0 0.28 11.4 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region vATP-synt_E PF01991.16 001288310.1_48623001_2 - 0.11 11.8 0.9 1.3 8.3 0.2 2.6 2 1 1 3 3 3 0 ATP synthase (E/31 kDa) subunit ChaC PF04752.10 001288534.1_48623001_2 - 1.3e-46 158.7 0.0 1.7e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Ribosomal_L19e PF01280.18 001288084.1_48622001_1 - 1.1e-65 219.9 13.2 1.1e-65 219.9 13.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e DUF106 PF01956.14 001288084.1_48622001_1 - 0.014 15.0 0.6 0.041 13.5 0.0 1.9 1 1 1 2 2 2 0 Integral membrane protein DUF106 NAM PF02365.13 001288086.1_48623001_1 - 8.6e-26 90.5 0.5 1.4e-25 89.8 0.5 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein CENP-F_leu_zip PF10473.7 001288086.1_48623001_1 - 0.048 13.6 0.1 0.08 12.8 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 adh_short_C2 PF13561.4 001288311.1_48622001_1 - 1.1e-57 195.2 0.1 1.4e-57 194.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001288311.1_48622001_1 - 3.3e-53 179.9 0.2 4e-53 179.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001288311.1_48622001_1 - 6.6e-16 58.6 0.1 1.2e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.19 001288311.1_48622001_1 - 0.0042 16.5 0.0 0.0091 15.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cmc1 PF08583.8 001288311.1_48622001_1 - 0.12 12.3 0.4 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1776 PF08643.8 001288311.1_48622001_1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.19 001287843.1_48624001_1 - 2.1e-45 154.9 0.0 2.9e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001287843.1_48624001_1 - 3.2e-28 98.9 0.0 5.8e-27 94.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.17 001287843.1_48624001_1 - 3e-08 32.9 0.0 4.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001287843.1_48624001_1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001287843.1_48624001_1 - 1.7e-05 24.0 0.0 0.00086 18.4 0.0 2.5 3 0 0 3 3 3 1 Male sterility protein Polysacc_synt_2 PF02719.13 001287843.1_48624001_1 - 0.00037 19.6 0.0 0.0083 15.2 0.1 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001287843.1_48624001_1 - 0.014 14.4 0.0 0.044 12.8 0.0 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.23 001288087.1_48623001_1 - 1.3e-72 244.3 0.0 1.5e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288087.1_48623001_1 - 7e-34 117.1 0.0 9.1e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001288087.1_48623001_1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001288087.1_48623001_1 - 0.065 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase MitMem_reg PF13012.4 001288537.1_48623001_1 - 6.3e-37 126.3 0.8 1.1e-36 125.5 0.8 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.19 001288537.1_48623001_1 - 6.2e-30 103.5 0.0 1.1e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease cEGF PF12662.5 001288537.1_48623001_1 - 0.011 15.6 0.3 0.018 14.9 0.3 1.3 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF PF00008.25 001288537.1_48623001_1 - 0.13 12.4 0.8 0.23 11.7 0.8 1.3 1 0 0 1 1 1 0 EGF-like domain CDC14 PF08045.9 001288312.1_48622001_1 - 1.9e-11 43.6 0.0 2.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Cell division control protein 14, SIN component CDP-OH_P_transf PF01066.19 001288313.1_48622001_1 - 1.1e-14 54.8 1.2 1.1e-14 54.8 1.2 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Tad PF13400.4 001288313.1_48622001_1 - 3 8.1 5.9 0.59 10.4 0.7 2.5 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Myb_DNA-binding PF00249.29 001287845.1_48623001_1 - 3e-30 104.0 4.1 1.5e-15 56.9 1.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001287845.1_48623001_1 - 5.7e-18 64.8 0.2 3e-09 36.8 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Nucleoside_tran PF01733.16 001288089.1_48623001_1 - 2.6e-37 128.8 1.8 4.8e-37 127.8 1.8 1.5 1 0 0 1 1 1 1 Nucleoside transporter DUF3700 PF12481.6 001288092.1_48623001_1 - 1.8e-85 285.8 0.0 2.4e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Aluminium induced protein GATase_7 PF13537.4 001288092.1_48623001_1 - 5.7e-12 45.5 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001288092.1_48623001_1 - 8.9e-09 35.5 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Spermine_synth PF01564.15 001288093.1_48623001_1 - 6.8e-97 323.2 0.0 8.3e-97 322.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_25 PF13649.4 001288093.1_48623001_1 - 3.9e-05 24.1 0.0 7.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.9 001288093.1_48623001_1 - 0.0033 17.2 0.0 0.0051 16.5 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.12 001288093.1_48623001_1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Kelch_1 PF01344.23 001288093.1_48623001_1 - 0.034 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Kelch motif DRE2_N PF16803.3 001288093.1_48623001_1 - 0.081 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus Methyltransf_11 PF08241.10 001288093.1_48623001_1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.4 001288093.1_48623001_1 - 0.15 13.0 0.0 0.26 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.15 001288093.1_48623001_1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DIOX_N PF14226.4 001287849.1_48623001_1 - 1.7e-32 112.5 0.0 2.9e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.18 001287849.1_48623001_1 - 6.2e-22 77.9 0.0 1.1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Alpha-amylase_C PF02806.16 001288538.1_48626001_2 - 3e-22 78.7 0.0 8.2e-22 77.3 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.16 001288538.1_48626001_2 - 2.5e-19 69.3 0.1 7.4e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.22 001288538.1_48626001_2 - 4.5e-16 59.2 1.2 7.2e-13 48.7 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.4 001288538.1_48626001_2 - 0.019 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF2470 PF10615.7 001288539.1_48623001_1 - 1.9e-14 53.8 0.0 3.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyrid_oxidase_2 PF13883.4 001288539.1_48623001_1 - 5.1e-12 46.0 0.0 1.4e-11 44.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.18 001288539.1_48623001_1 - 1.3e-09 38.0 0.0 2.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UBX PF00789.18 001288539.1_48623001_1 - 0.08 13.0 0.2 0.28 11.3 0.0 2.0 2 1 0 2 2 2 0 UBX domain DUF778 PF05608.10 001287851.1_48622001_3 - 5.5e-42 144.1 2.1 4.4e-21 75.9 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) AAA PF00004.27 001288095.1_48624001_2 - 1.5e-39 135.3 0.0 3.4e-39 134.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 001288095.1_48624001_2 - 2.6e-06 27.6 0.6 0.012 15.7 0.1 2.3 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.11 001288095.1_48624001_2 - 9.7e-05 21.5 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.12 001288095.1_48624001_2 - 0.0001 22.4 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001288095.1_48624001_2 - 0.0002 21.3 0.1 0.00081 19.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001288095.1_48624001_2 - 0.00029 21.1 0.4 0.0019 18.5 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.10 001288095.1_48624001_2 - 0.0021 17.2 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus ATPase PF06745.11 001288095.1_48624001_2 - 0.0083 15.4 0.2 0.21 10.8 0.1 2.3 1 1 1 2 2 2 1 KaiC RNA_helicase PF00910.20 001288095.1_48624001_2 - 0.015 15.5 0.0 0.043 14.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.15 001288095.1_48624001_2 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.11 001288095.1_48624001_2 - 0.022 13.6 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.9 001288095.1_48624001_2 - 0.031 14.0 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.4 001288095.1_48624001_2 - 0.035 14.5 0.0 0.3 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.4 001288095.1_48624001_2 - 0.047 13.3 0.3 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.4 001288095.1_48624001_2 - 0.067 13.3 0.0 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.24 001288095.1_48624001_2 - 0.076 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF1128 PF06569.9 001288095.1_48624001_2 - 0.083 12.8 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) TsaE PF02367.15 001288095.1_48624001_2 - 0.089 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.4 001288095.1_48624001_2 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.19 001288095.1_48624001_2 - 0.11 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.10 001288095.1_48624001_2 - 0.13 12.0 0.1 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain NIR_SIR PF01077.20 001288094.1_48624001_1 - 1.3e-49 167.7 0.0 3.1e-36 124.2 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.15 001288094.1_48624001_1 - 1.5e-40 136.7 0.0 8.4e-20 70.3 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Polyketide_cyc2 PF10604.7 001288096.1_48623001_1 - 3.2e-18 66.2 0.0 4.3e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1857 PF08982.9 001288096.1_48623001_1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) eRF1_2 PF03464.13 001288540.1_48624001_1 - 7.7e-43 145.9 0.0 1.3e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.13 001288540.1_48624001_1 - 6.6e-34 116.7 0.1 1.4e-33 115.6 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.13 001288540.1_48624001_1 - 1.6e-19 70.1 0.0 2.7e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 She2p PF11435.6 001288540.1_48624001_1 - 0.028 14.0 0.3 0.045 13.3 0.3 1.3 1 0 0 1 1 1 0 RNA binding protein She2p Annexin PF00191.18 001287853.1_48623001_1 - 5.4e-64 212.0 5.6 9.3e-17 60.7 0.0 4.2 4 0 0 4 4 4 4 Annexin HNOB PF07700.13 001287853.1_48623001_1 - 0.11 12.3 0.1 0.74 9.6 0.0 2.3 2 1 0 3 3 3 0 Haem-NO-binding Thioredoxin PF00085.18 001288541.1_48623001_3 - 4.7e-69 228.8 0.1 1.3e-34 118.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.10 001288541.1_48623001_3 - 5.7e-24 84.7 1.6 1.5e-23 83.3 1.6 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.11 001288541.1_48623001_3 - 9.9e-18 64.4 0.0 9.8e-08 31.5 0.0 2.5 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 001288541.1_48623001_3 - 1.7e-15 57.3 0.5 1.3e-06 28.7 0.0 3.2 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.19 001288541.1_48623001_3 - 3.6e-09 36.5 0.1 0.0038 17.0 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.4 001288541.1_48623001_3 - 2.5e-08 34.0 0.3 0.00013 21.8 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001288541.1_48623001_3 - 1.4e-07 31.6 0.2 0.24 11.6 0.0 4.5 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.4 001288541.1_48623001_3 - 1.6e-07 31.3 0.1 0.0015 18.5 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.8 001288541.1_48623001_3 - 0.00023 20.7 0.1 0.34 10.5 0.0 2.4 2 0 0 2 2 2 2 Redoxin HyaE PF07449.9 001288541.1_48623001_3 - 0.00047 20.0 0.0 0.042 13.7 0.0 2.7 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.4 001288541.1_48623001_3 - 0.029 14.0 0.0 0.63 9.7 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin TraF PF13728.4 001288541.1_48623001_3 - 0.034 13.9 0.0 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein DDE_Tnp_1_2 PF13586.4 001288541.1_48623001_3 - 0.058 13.6 0.0 20 5.5 0.0 2.7 2 0 0 2 2 2 0 Transposase DDE domain Thioredoxin_4 PF13462.4 001288541.1_48623001_3 - 0.11 12.5 1.3 13 5.8 0.1 2.7 2 1 0 2 2 2 0 Thioredoxin tify PF06200.12 001288317.1_48624001_1 - 6.6e-20 70.0 0.2 1.6e-19 68.7 0.0 1.8 2 0 0 2 2 2 1 tify domain CCT_2 PF09425.8 001288317.1_48624001_1 - 3.7e-13 49.0 2.6 6.4e-13 48.2 2.6 1.4 1 0 0 1 1 1 1 Divergent CCT motif MatE PF01554.16 001287854.1_48624001_3 - 5e-63 211.4 36.4 2.4e-37 127.9 11.6 3.1 3 0 0 3 3 3 2 MatE FAM176 PF14851.4 001287854.1_48624001_3 - 0.26 10.8 3.0 7.8 6.0 0.2 3.6 4 0 0 4 4 4 0 FAM176 family Baculo_11_kDa PF06143.9 001287854.1_48624001_3 - 0.56 9.7 0.0 0.56 9.7 0.0 2.6 4 0 0 4 4 4 0 Baculovirus 11 kDa family RRM_1 PF00076.20 001288318.1_48622001_1 - 7e-15 54.5 0.1 1.1e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001288318.1_48622001_1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Spo7_2_N PF15407.4 001288318.1_48622001_1 - 0.38 10.3 0.0 0.38 10.3 0.0 2.1 3 0 0 3 3 3 0 Sporulation protein family 7 DUF563 PF04577.12 001288099.1_48625001_1 - 1.4e-24 87.2 0.0 2.4e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Tryp_alpha_amyl PF00234.20 001288098.1_48621001_2 - 1.4e-09 38.1 0.2 1.9e-09 37.7 0.2 1.1 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family LTP_2 PF14368.4 001288098.1_48621001_2 - 0.001 19.0 3.0 0.0015 18.5 3.0 1.3 1 0 0 1 1 1 1 Probable lipid transfer Phage_holin_3_1 PF05106.10 001288098.1_48621001_2 - 0.017 15.4 0.3 0.027 14.7 0.3 1.3 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) LEA_3 PF03242.11 001288542.1_48622001_1 - 1.5e-31 108.8 0.1 2e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein Ribosomal_S6e PF01092.17 001288100.1_48623001_3 - 6.5e-58 194.0 0.0 1.1e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e DUF5105 PF17118.3 001288100.1_48623001_3 - 0.01 15.5 0.5 0.015 14.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) Pectinesterase PF01095.17 001287856.1_48624001_1 - 2.1e-148 492.8 0.9 2.6e-148 492.4 0.9 1.1 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.13 001287856.1_48624001_1 - 6.2e-14 52.5 1.9 6.2e-14 52.5 1.9 1.7 2 0 0 2 2 2 1 Plant invertase/pectin methylesterase inhibitor Ferrochelatase PF00762.17 001288319.1_48625001_3 - 4e-111 371.0 0.0 4.8e-111 370.7 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.15 001288319.1_48625001_3 - 0.00026 21.1 0.1 0.22 11.7 0.0 2.5 2 0 0 2 2 2 2 CbiX CbiK PF06180.9 001288319.1_48625001_3 - 0.088 12.0 0.0 4.2 6.5 0.0 2.5 2 1 0 2 2 2 0 Cobalt chelatase (CbiK) POT1 PF02765.15 001288320.1_48623001_1 - 2e-27 95.7 0.0 3e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.3 001288320.1_48623001_1 - 5.2e-08 32.8 0.0 3e-06 27.1 0.0 2.9 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein tRNA_anti-codon PF01336.23 001288320.1_48623001_1 - 0.014 15.2 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain AUX_IAA PF02309.14 001288544.1_48624001_3 - 1.1e-91 306.9 0.0 1.3e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 AUX/IAA family Cytokin-bind PF09265.8 001288101.1_48624001_1 - 2.4e-115 384.6 0.2 3.1e-115 384.3 0.2 1.1 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 001288101.1_48624001_1 - 4.8e-18 65.1 0.1 7.4e-18 64.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AUX_IAA PF02309.14 001288102.1_48622001_1 - 2.4e-81 273.0 2.4 1.1e-80 270.8 2.4 1.7 1 1 0 1 1 1 1 AUX/IAA family Ion_trans PF00520.29 001288546.1_48625001_1 - 8.4e-35 120.0 15.4 1.1e-34 119.6 15.4 1.2 1 0 0 1 1 1 1 Ion transport protein KHA PF11834.6 001288546.1_48625001_1 - 6.4e-23 80.5 0.1 1.5e-22 79.3 0.1 1.7 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel cNMP_binding PF00027.27 001288546.1_48625001_1 - 4e-14 52.3 0.1 1.8e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.14 001288546.1_48625001_1 - 2.6e-11 43.2 3.0 7.7e-11 41.7 3.0 1.9 1 1 0 1 1 1 1 Ion channel Thioredoxin_4 PF13462.4 001287860.1_48622001_2 - 1.9e-06 28.0 0.0 2.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.18 001287860.1_48622001_2 - 3.8e-05 23.4 0.0 0.0017 18.0 0.0 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain MBF1 PF08523.8 001288322.1_48622001_1 - 7.1e-24 83.9 6.7 9.3e-24 83.5 5.6 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.20 001288322.1_48622001_1 - 2.1e-12 46.8 1.8 3.9e-12 45.9 1.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.4 001288322.1_48622001_1 - 0.00071 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.5 001288322.1_48622001_1 - 0.0011 18.8 0.5 0.002 18.0 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.3 001288322.1_48622001_1 - 0.014 15.3 0.4 0.066 13.2 0.1 1.9 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_37 PF13744.4 001288322.1_48622001_1 - 0.063 13.1 0.8 0.12 12.2 0.8 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ArsC PF03960.13 001288322.1_48622001_1 - 0.55 10.2 2.4 1 9.3 0.4 2.2 1 1 1 2 2 2 0 ArsC family NYD-SP28 PF14772.4 001288322.1_48622001_1 - 4.2 7.3 9.1 5.3 7.0 7.1 2.3 1 1 1 2 2 2 0 Sperm tail Ribosomal_L29 PF00831.21 001288103.1_48622001_2 - 8.1e-18 64.0 1.8 8.1e-18 64.0 1.8 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_L13 PF00572.16 001288547.1_48622001_1 - 7.3e-10 39.0 0.0 2.1e-08 34.3 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L18A PF01775.15 001288323.1_48622001_1 - 1.4e-53 180.0 3.4 1.9e-53 179.5 3.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ldh_1_C PF02866.16 001288105.1_48623001_1 - 4.7e-48 163.2 0.0 8.2e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.21 001288105.1_48623001_1 - 2.9e-47 160.2 0.1 4.2e-47 159.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.17 001288105.1_48623001_1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.14 001288105.1_48623001_1 - 0.034 13.5 0.4 3.8 6.9 0.6 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase PBP PF01161.18 001288549.1_48622001_1 - 9.7e-14 51.7 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Iso_dh PF00180.18 001288324.1_48624001_1 - 3.4e-79 266.4 0.0 4.1e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase LysM PF01476.18 001288550.1_48623001_1 - 1.9e-18 66.2 1.4 2.3e-07 30.7 0.0 3.7 4 0 0 4 4 4 2 LysM domain HTH_7 PF02796.13 001288550.1_48623001_1 - 0.00087 19.2 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.4 001288550.1_48623001_1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain EF1G PF00647.17 001287864.1_48624001_2 - 2.4e-42 143.2 1.1 6.2e-41 138.6 0.1 2.6 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.18 001287864.1_48624001_2 - 3.6e-13 49.5 0.0 8.3e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001287864.1_48624001_2 - 1.8e-10 40.7 0.6 3.5e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001287864.1_48624001_2 - 1.2e-07 31.9 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001287864.1_48624001_2 - 2.5e-06 27.2 0.0 5.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001287864.1_48624001_2 - 2e-05 24.7 0.0 4.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001287864.1_48624001_2 - 2.5e-05 24.3 0.0 6.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HABP4_PAI-RBP1 PF04774.13 001287864.1_48624001_2 - 1.3 9.7 7.5 0.13 13.0 2.6 1.7 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Pollen_allerg_1 PF01357.19 001288325.1_48623001_1 - 5.3e-26 90.4 0.1 8.6e-26 89.7 0.1 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001288325.1_48623001_1 - 2e-19 69.5 0.4 2.9e-18 65.8 0.1 2.4 2 0 0 2 2 2 1 Lytic transglycolase Alg14 PF08660.9 001288106.1_48623001_1 - 3.3e-42 144.2 0.0 6.8e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Alg14 PF08660.9 001288106.1_48623001_2 - 1.1e-16 61.2 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like RRM_1 PF00076.20 001288551.1_48624001_3 - 9.2e-55 182.2 0.0 4.8e-18 64.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001288551.1_48624001_3 - 3.2e-10 39.5 0.0 3e-05 23.5 0.0 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001288551.1_48624001_3 - 3.4e-08 33.4 0.1 0.00014 21.8 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.9 001288551.1_48624001_3 - 9.9e-08 31.8 1.1 6.6e-05 22.8 0.0 3.3 4 0 0 4 4 4 2 RNA binding motif DUF1866 PF08952.9 001288551.1_48624001_3 - 0.00088 19.0 0.0 0.0054 16.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) RRM_occluded PF16842.3 001288551.1_48624001_3 - 0.0025 17.5 0.0 0.027 14.2 0.0 2.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif PHM7_cyt PF14703.4 001288551.1_48624001_3 - 0.017 15.2 0.2 2.8 8.0 0.1 3.0 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Redoxin PF08534.8 001288326.1_48621001_1 - 1.3e-33 115.6 0.0 1.4e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.19 001288326.1_48621001_1 - 7.6e-14 51.6 0.0 9e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ntox46 PF15538.4 001288326.1_48621001_1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 46 BSP PF04450.10 001288107.1_48622001_2 - 6.4e-81 270.9 0.1 7.6e-81 270.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.7 001288107.1_48622001_2 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 SprT-like family CCT PF06203.12 001287866.1_48624001_2 - 6.5e-18 64.4 14.8 1.2e-17 63.5 14.8 1.5 1 0 0 1 1 1 1 CCT motif zf-B_box PF00643.22 001287866.1_48624001_2 - 1e-09 38.3 12.4 2.3e-07 30.7 0.5 2.7 2 1 1 3 3 3 2 B-box zinc finger CEBP_ZZ PF16366.3 001287866.1_48624001_2 - 0.9 9.7 23.4 0.4 10.8 6.9 2.8 2 1 1 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_9 PF13901.4 001287866.1_48624001_2 - 2.2 8.1 14.6 0.45 10.3 2.0 2.5 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon GTP_EFTU PF00009.25 001288552.1_48624001_1 - 2.5e-45 154.3 0.1 8.3e-45 152.6 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001288552.1_48624001_1 - 9.7e-39 132.0 0.0 1.8e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001288552.1_48624001_1 - 4.3e-14 52.5 0.3 1.1e-13 51.2 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.4 001288552.1_48624001_1 - 0.028 14.3 1.3 0.053 13.4 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA_22 PF13401.4 001288552.1_48624001_1 - 0.083 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.26 001288327.1_48624001_3 - 2.7e-23 83.4 1.1 3.4e-23 83.1 0.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.3 001288327.1_48624001_3 - 3.9e-21 75.3 1.0 3.9e-21 75.3 1.0 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.4 001288327.1_48624001_3 - 6.8e-18 65.2 0.2 2.1e-17 63.6 0.2 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Ribosomal_S2 PF00318.18 001288110.1_48623001_1 - 1.3e-27 96.3 0.0 4.6e-13 48.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.3 001288110.1_48623001_1 - 0.0032 18.7 6.6 0.0067 17.6 6.6 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus RRM_5 PF13893.4 001287868.1_48623001_2 - 2.4e-37 127.2 4.1 2.6e-27 94.7 0.0 3.8 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 001287868.1_48623001_2 - 5.7e-29 99.6 0.0 2.9e-08 33.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001287868.1_48623001_2 - 5.5e-09 35.6 0.8 0.022 14.5 0.1 4.0 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_7 PF16367.3 001287868.1_48623001_2 - 0.1 12.6 0.0 6.8 6.8 0.0 3.5 3 0 0 3 3 3 0 RNA recognition motif 2OG-FeII_Oxy PF03171.18 001288553.1_48623001_1 - 4.7e-27 94.3 0.0 8.4e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001288553.1_48623001_1 - 4.6e-13 49.8 0.0 8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_transf_5 PF08323.9 001288111.1_48625001_3 - 7.5e-32 110.8 0.0 1e-31 110.3 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.4 001288111.1_48625001_3 - 0.00054 19.9 0.3 0.018 14.9 0.1 3.1 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Uds1 PF15456.4 001288111.1_48625001_3 - 0.16 12.0 1.8 0.35 10.9 1.5 1.7 1 1 0 1 1 1 0 Up-regulated During Septation Glyco_trans_4_4 PF13579.4 001288111.1_48625001_3 - 0.19 12.0 0.0 0.95 9.8 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Oxysterol_BP PF01237.16 001287869.1_48624001_3 - 3.7e-103 345.1 0.0 4.5e-103 344.8 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Prot_inhib_II PF02428.13 001288328.1_48622001_2 - 3.3e-36 123.4 28.7 1.3e-18 67.0 9.3 2.2 2 0 0 2 2 2 2 Potato type II proteinase inhibitor family Transferase PF02458.13 001288554.1_48623001_1 - 7e-103 344.5 0.0 8.2e-103 344.2 0.0 1.0 1 0 0 1 1 1 1 Transferase family MAR_sialic_bdg PF10564.7 001288554.1_48623001_1 - 0.041 13.8 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat RRM_1 PF00076.20 001288329.1_48624001_1 - 3.5e-22 77.9 0.3 3.9e-09 36.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001288329.1_48624001_1 - 1.8e-10 40.3 0.0 1.7e-05 24.3 0.0 2.7 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.4 001288329.1_48624001_1 - 0.0062 16.3 0.2 0.54 9.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) NtCtMGAM_N PF16863.3 001288329.1_48624001_1 - 0.087 12.9 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Glyco_hydro_28 PF00295.15 001287871.1_48624001_2 - 9.1e-37 126.7 2.2 1e-36 126.5 1.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.5 001287871.1_48624001_2 - 5.1e-06 26.4 3.1 0.00014 21.7 3.1 2.9 1 1 0 1 1 1 1 Pectate lyase superfamily protein Beta_helix PF13229.4 001287871.1_48624001_2 - 1.1e-05 25.1 10.1 0.014 15.1 0.2 3.4 2 1 0 4 4 4 2 Right handed beta helix region Fels1 PF05666.9 001287871.1_48624001_2 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like WD40 PF00400.30 001287872.1_48623001_1 - 4.9e-15 55.5 11.0 8e-06 26.4 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.3 001287872.1_48623001_1 - 0.046 12.6 0.2 1.3 7.8 0.0 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.6 001287872.1_48623001_1 - 0.076 11.5 0.0 0.35 9.3 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ion_trans PF00520.29 001288330.1_48626001_2 - 3.9e-35 121.1 18.9 3.9e-35 121.1 18.9 1.7 2 0 0 2 2 2 1 Ion transport protein Ank_2 PF12796.5 001288330.1_48626001_2 - 7.1e-22 77.7 3.4 1.3e-11 44.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) KHA PF11834.6 001288330.1_48626001_2 - 3.1e-21 75.1 0.0 7e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Ank_4 PF13637.4 001288330.1_48626001_2 - 1e-17 64.1 7.4 1.1e-07 32.2 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.4 001288330.1_48626001_2 - 3.9e-17 61.9 3.5 3e-07 30.5 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) cNMP_binding PF00027.27 001288330.1_48626001_2 - 1.6e-15 56.7 0.0 2.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.14 001288330.1_48626001_2 - 2.7e-13 49.6 5.4 2.7e-13 49.6 5.4 2.0 2 0 0 2 2 2 1 Ion channel Ank PF00023.28 001288330.1_48626001_2 - 3.9e-12 45.9 5.1 4.3e-07 30.0 0.1 4.4 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.4 001288330.1_48626001_2 - 2.1e-10 39.8 3.5 0.0039 17.4 0.1 6.0 4 1 1 5 5 5 2 Ankyrin repeat GDP_Man_Dehyd PF16363.3 001288117.1_48623001_1 - 1.9e-63 214.7 0.0 2.2e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.19 001288117.1_48623001_1 - 3.1e-51 174.0 0.0 3.8e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.13 001288117.1_48623001_1 - 5.4e-15 55.2 0.0 2.6e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.17 001288117.1_48623001_1 - 4e-14 52.1 0.1 1.3e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.15 001288117.1_48623001_1 - 7.1e-08 31.7 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.23 001288117.1_48623001_1 - 1.9e-06 27.3 0.0 4.1e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.4 001288117.1_48623001_1 - 2.4e-06 27.4 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001288117.1_48623001_1 - 0.0001 21.4 0.0 0.00025 20.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein KR PF08659.8 001288117.1_48623001_1 - 0.00019 21.3 0.0 0.00056 19.7 0.0 1.7 1 1 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.12 001288117.1_48623001_1 - 0.0027 17.2 0.0 0.014 14.9 0.0 2.0 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.16 001288117.1_48623001_1 - 0.0033 17.2 0.0 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_25 PF13481.4 001288117.1_48623001_1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L10 PF00466.18 001288331.1_48622001_1 - 2.6e-20 72.3 0.1 3.8e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 F-actin_cap_A PF01267.15 001288331.1_48622001_1 - 0.0062 15.9 1.0 0.0092 15.3 0.6 1.5 2 0 0 2 2 2 1 F-actin capping protein alpha subunit Herpes_UL14 PF03580.12 001288331.1_48622001_1 - 0.13 12.3 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Ribosomal_L5e PF17144.2 001287874.1_48623001_3 - 2.4e-83 277.8 0.1 5.4e-83 276.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.4 001287874.1_48623001_3 - 9.3e-35 119.3 2.0 9.3e-35 119.3 2.0 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ldh_1_C PF02866.16 001288558.1_48623001_1 - 5.2e-35 120.7 0.0 7.7e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.21 001288558.1_48623001_1 - 1.5e-34 118.9 0.9 2.5e-34 118.3 0.9 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DcuC PF03606.13 001288558.1_48623001_1 - 0.078 11.3 0.1 0.12 10.7 0.1 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier NAC PF01849.16 001288118.1_48622001_2 - 1.3e-19 69.8 0.2 2.9e-19 68.7 0.2 1.6 1 0 0 1 1 1 1 NAC domain SNF2_N PF00176.21 001288118.1_48622001_2 - 0.017 13.7 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain ADK PF00406.20 001288118.1_48622001_2 - 0.024 14.6 0.1 0.049 13.6 0.0 1.4 1 1 0 1 1 1 0 Adenylate kinase Beta_elim_lyase PF01212.19 001288332.1_48623001_1 - 8.8e-92 307.4 0.1 1.2e-91 307.0 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.15 001288332.1_48623001_1 - 0.00037 19.8 0.0 0.00066 19.0 0.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.19 001288332.1_48623001_1 - 0.0011 17.5 0.1 0.011 14.3 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.18 001288332.1_48623001_1 - 0.027 12.9 0.0 0.044 12.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.17 001288332.1_48623001_1 - 0.038 12.8 0.1 0.11 11.3 0.0 1.7 1 1 1 2 2 2 0 Aminotransferase class-V Rnk_N PF14760.4 001288332.1_48623001_1 - 0.39 11.1 1.6 3.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Rnk N-terminus Asp PF00026.21 001288120.1_48624001_1 - 1e-129 432.3 2.5 1.4e-129 432.0 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001288120.1_48624001_1 - 2.7e-13 50.4 0.5 9.1e-12 45.5 0.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal SapB_2 PF03489.15 001288120.1_48624001_1 - 7e-13 48.3 0.1 1.8e-12 47.0 0.1 1.8 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.13 001288120.1_48624001_1 - 3.6e-12 45.9 1.5 1e-11 44.4 1.5 1.9 1 0 0 1 1 1 1 Saposin-like type B, region 1 TAXi_C PF14541.4 001288120.1_48624001_1 - 0.00048 19.8 0.0 0.00097 18.8 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.4 001288120.1_48624001_1 - 0.057 14.0 0.3 1.6 9.3 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease Acetyltransf_1 PF00583.23 001287876.1_48622001_2 - 2.7e-13 50.1 0.0 3.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.5 001287876.1_48622001_2 - 2.9e-10 40.0 0.0 4.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 001287876.1_48622001_2 - 1.7e-09 37.8 0.0 2.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.8 001287876.1_48622001_2 - 1.9e-06 27.6 0.0 3.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.5 001287876.1_48622001_2 - 0.00072 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ras PF00071.20 001288334.1_48622001_3 - 9.5e-50 168.2 0.0 1.2e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001288334.1_48622001_3 - 2.4e-29 101.9 0.0 4e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001288334.1_48622001_3 - 4.4e-11 42.4 0.0 6.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.20 001288334.1_48622001_3 - 1.9e-05 24.9 0.1 8.1e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.21 001288334.1_48622001_3 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pox_A32 PF04665.10 001288334.1_48622001_3 - 0.019 14.3 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.4 001288334.1_48622001_3 - 0.057 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.11 001288334.1_48622001_3 - 0.062 12.5 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 KaiC DUF258 PF03193.14 001288334.1_48622001_3 - 0.064 13.0 0.0 8.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Ring_hydroxyl_A PF00848.17 001288122.1_48623001_1 - 5.2e-28 98.3 0.1 3.2e-26 92.5 0.1 2.3 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.24 001288122.1_48623001_1 - 1e-16 60.5 0.2 1.8e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Glycolytic PF00274.17 001287879.1_48623001_1 - 1.6e-143 477.5 0.0 2.1e-143 477.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.17 001287879.1_48623001_3 - 0.012 14.3 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I ubiquitin PF00240.21 001288669.1_48622001_1 - 4.9e-34 115.8 0.4 8.1e-34 115.0 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.17 001288669.1_48622001_1 - 1.1e-27 95.8 2.2 2.7e-27 94.6 2.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.6 001288669.1_48622001_1 - 5.6e-16 58.0 0.6 5.6e-16 58.0 0.6 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001288669.1_48622001_1 - 4.9e-05 23.6 0.4 0.0003 21.0 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.4 001288669.1_48622001_1 - 0.00077 19.4 0.8 0.0016 18.4 0.8 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001288669.1_48622001_1 - 0.013 16.0 1.0 0.02 15.3 1.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain LIME1 PF15332.4 001288669.1_48622001_2 - 0.021 14.2 1.6 0.029 13.7 1.6 1.2 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 BET PF17035.3 001288337.1_48624001_1 - 7.7e-23 80.3 1.0 1.6e-22 79.3 1.0 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.23 001288337.1_48624001_1 - 2.6e-18 65.7 0.0 5.8e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain RRM_1 PF00076.20 001287880.1_48623001_2 - 1.4e-15 56.7 0.2 2.4e-15 56.0 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.9 001287880.1_48623001_2 - 0.0081 16.1 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif Glycolytic PF00274.17 001288338.1_48623001_1 - 2.3e-173 575.7 0.0 2.6e-173 575.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Tubulin PF00091.23 001287882.1_48624001_1 - 1.5e-69 234.0 0.0 2.4e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001287882.1_48624001_1 - 2.4e-40 137.5 0.3 3.7e-40 136.9 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.4 001287882.1_48624001_1 - 0.00068 18.8 0.1 0.002 17.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Misat_Tub_SegII PF10644.7 001287882.1_48624001_1 - 0.0013 18.9 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001287882.1_48624001_1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain GST_N_3 PF13417.4 001288124.1_48623001_3 - 4.7e-18 65.2 0.0 8.8e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001288124.1_48623001_3 - 2.7e-14 53.1 0.0 4.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001288124.1_48623001_3 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001288124.1_48623001_3 - 3.6e-05 23.5 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 001288124.1_48623001_3 - 0.00046 20.8 0.0 0.00096 19.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.4 001288124.1_48623001_3 - 0.011 15.7 0.0 0.033 14.2 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TPR_14 PF13428.4 001288673.1_48623001_2 - 5.4e-09 36.0 3.4 0.00053 20.5 0.2 3.8 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.4 001288673.1_48623001_2 - 7.1e-09 35.9 0.6 4.7e-05 23.7 0.6 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.15 001288673.1_48623001_2 - 2.4e-06 27.1 6.8 0.0012 18.7 0.1 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.4 001288673.1_48623001_2 - 8.5e-06 26.2 1.2 0.0025 18.3 0.3 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.26 001288673.1_48623001_2 - 0.00013 21.5 2.9 0.026 14.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.4 001288673.1_48623001_2 - 0.0006 19.7 3.9 0.15 12.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.4 001288673.1_48623001_2 - 0.0015 18.5 0.9 0.037 14.0 0.2 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.4 001288673.1_48623001_2 - 0.0057 16.5 0.4 0.12 12.3 0.0 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.4 001288673.1_48623001_2 - 0.0058 15.7 2.1 0.0086 15.2 2.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.4 001288673.1_48623001_2 - 0.0087 16.5 3.2 20 6.0 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.6 001288673.1_48623001_2 - 0.013 14.3 1.0 0.12 11.1 0.3 2.1 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Wzy_C_2 PF11846.6 001288673.1_48623001_2 - 0.048 13.4 0.2 0.17 11.6 0.2 1.8 1 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.5 001288673.1_48623001_2 - 0.067 13.3 1.7 0.2 11.7 0.7 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.4 001288673.1_48623001_2 - 0.18 12.2 1.1 21 5.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.4 001288673.1_48623001_2 - 0.28 11.4 4.5 5.4 7.2 0.1 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat LTP_2 PF14368.4 001287883.1_48622001_3 - 1e-14 54.3 11.1 1.5e-14 53.8 11.1 1.2 1 0 0 1 1 1 1 Probable lipid transfer Tryp_alpha_amyl PF00234.20 001287883.1_48622001_3 - 2.1e-07 31.1 6.4 3.4e-07 30.4 6.4 1.3 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family 14-3-3 PF00244.18 001288341.1_48623001_3 - 5.8e-105 349.5 3.0 7.7e-105 349.1 3.0 1.2 1 0 0 1 1 1 1 14-3-3 protein DUF2890 PF11081.6 001288341.1_48623001_3 - 0.0076 16.2 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) AAL_decarboxy PF03306.11 001288341.1_48623001_3 - 0.035 13.3 0.7 0.054 12.7 0.7 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase Ribosomal_L6 PF00347.21 001287885.1_48622001_2 - 1.5e-24 86.3 2.0 1.1e-12 48.4 0.4 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 WRKY PF03106.13 001288675.1_48622001_2 - 2.8e-27 94.7 5.0 5.6e-27 93.7 5.0 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain Tubulin PF00091.23 001288342.1_48624001_2 - 2.9e-62 210.2 0.0 4.2e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001288342.1_48624001_2 - 5.4e-51 172.0 0.1 8.2e-51 171.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001288342.1_48624001_2 - 0.04 13.5 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Tubulin domain FixQ PF05545.9 001288342.1_48624001_3 - 0.37 10.7 4.2 0.96 9.3 4.2 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Glyco_hydro_32N PF00251.18 001288126.1_48624001_1 - 6.9e-110 367.2 6.7 9e-110 366.9 6.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.10 001288126.1_48624001_1 - 1.7e-14 54.2 0.0 6e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Peptidase_C1 PF00112.21 001288677.1_48623001_1 - 1.4e-73 247.5 6.5 1.9e-73 247.1 6.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001288677.1_48623001_1 - 1.1e-17 64.1 1.0 1.1e-17 64.1 1.0 1.8 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 001288677.1_48623001_1 - 0.0003 19.6 3.7 0.041 12.5 0.2 2.8 3 0 0 3 3 3 2 Peptidase C1-like family Lipoprotein_18 PF06804.9 001288677.1_48623001_1 - 0.11 11.4 0.0 0.36 9.7 0.0 1.7 2 0 0 2 2 2 0 NlpB/DapX lipoprotein Chloroa_b-bind PF00504.19 001288127.1_48623001_2 - 1e-48 165.8 0.0 1.4e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Glyco_hydro_32N PF00251.18 001287886.1_48624001_1 - 1.5e-106 356.3 6.3 2e-106 355.8 6.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.10 001287886.1_48624001_1 - 2.6e-16 60.0 0.2 6.5e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Peptidase_C13 PF01650.16 001288343.1_48624001_2 - 1.8e-113 378.2 0.0 4.4e-113 376.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase C13 family Peptidase_C14 PF00656.20 001288343.1_48624001_2 - 0.0075 16.1 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Barwin PF00967.15 001288679.1_48621001_1 - 3.5e-66 220.3 3.4 4.2e-66 220.1 3.4 1.0 1 0 0 1 1 1 1 Barwin family Gly_radical PF01228.19 001288679.1_48621001_1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycine radical Ribosomal_L35Ae PF01247.16 001288344.1_48621001_1 - 9e-47 157.1 0.5 1.1e-46 156.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.16 001288344.1_48621001_1 - 0.013 15.6 0.0 5.8 7.1 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Ion_trans_2 PF07885.14 001288128.1_48624001_3 - 9.3e-32 108.7 20.7 7e-17 61.1 5.4 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.29 001288128.1_48624001_3 - 3.3e-08 32.9 4.9 0.00013 21.2 0.2 2.4 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.24 001288128.1_48624001_3 - 0.0041 16.8 1.6 0.33 10.6 0.2 2.3 2 0 0 2 2 2 2 Ligand-gated ion channel EF-hand_1 PF00036.30 001288128.1_48624001_3 - 0.047 13.1 0.0 2.3 7.8 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.4 001288128.1_48624001_3 - 0.079 13.3 0.5 0.6 10.5 0.5 2.3 1 1 0 1 1 1 0 EF-hand domain pair Gate PF07670.12 001288128.1_48624001_3 - 0.08 13.1 5.8 0.44 10.7 5.8 2.3 1 1 0 1 1 1 0 Nucleoside recognition EF-hand_5 PF13202.4 001288128.1_48624001_3 - 0.086 12.3 0.7 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 EF hand Mito_carr PF00153.25 001287888.1_48623001_2 - 3.2e-50 167.9 3.0 3.4e-18 65.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ_C PF01556.16 001288130.1_48624001_3 - 1.1e-35 122.8 0.2 1.8e-35 122.1 0.2 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 001288130.1_48624001_3 - 2.5e-22 78.7 1.0 6.7e-22 77.3 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.17 001288130.1_48624001_3 - 6.2e-15 55.2 21.1 1.3e-14 54.2 21.1 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.17 001288130.1_48624001_3 - 0.04 13.8 8.2 1.3 8.9 1.5 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.3 001288130.1_48624001_3 - 0.41 10.5 24.9 0.13 12.1 2.8 3.0 2 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein GAGA_bind PF06217.10 001287889.1_48623001_3 - 1.7e-90 304.2 2.3 2e-90 303.9 2.3 1.0 1 0 0 1 1 1 1 GAGA binding protein-like family Cyclin_N PF00134.21 001288346.1_48623001_1 - 3.5e-27 94.6 1.0 8e-27 93.4 1.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001288346.1_48623001_1 - 1.7e-19 69.9 0.0 6e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain eIF-1a PF01176.17 001288682.1_48622001_3 - 5.2e-22 77.3 0.1 7.5e-22 76.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L22 PF00237.17 001287890.1_48622001_3 - 1.4e-37 128.1 0.1 1.9e-37 127.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L3 PF00297.20 001288347.1_48623001_1 - 1.7e-193 642.5 9.8 2e-193 642.3 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 WD40 PF00400.30 001315540.1_48624001_2 - 1.5e-09 38.2 8.2 0.14 12.9 0.1 6.4 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001315540.1_48624001_2 - 1.6e-08 34.6 0.1 0.0031 17.6 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.31 001315540.1_48624001_2 - 1.6e-06 27.7 0.5 1.6e-06 27.7 0.5 1.9 2 0 0 2 2 2 1 F-box domain Frtz PF11768.6 001315540.1_48624001_2 - 0.00019 19.8 0.0 0.021 13.0 0.0 2.2 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.3 001315540.1_48624001_2 - 0.00034 19.9 0.1 0.16 11.1 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain F-box-like PF12937.5 001315540.1_48624001_2 - 0.00059 19.5 0.5 0.00059 19.5 0.5 1.8 2 0 0 2 2 2 1 F-box-like PQQ_3 PF13570.4 001315540.1_48624001_2 - 0.0077 16.6 1.4 7 7.2 0.1 3.9 4 0 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.4 001315540.1_48624001_2 - 0.035 13.6 0.1 0.22 10.9 0.1 2.0 1 1 0 2 2 2 0 PQQ-like domain ABC2_membrane PF01061.22 001287891.1_48629001_1 - 2.9e-98 327.3 70.6 1.3e-57 194.5 33.6 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.25 001287891.1_48629001_1 - 7.5e-38 130.0 0.0 3.3e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_assoc PF08370.9 001287891.1_48629001_1 - 1.3e-27 95.1 0.2 1.3e-27 95.1 0.2 3.5 3 0 0 3 3 2 1 Plant PDR ABC transporter associated ABC_trans_N PF14510.4 001287891.1_48629001_1 - 7.7e-12 45.5 0.0 1.7e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.4 001287891.1_48629001_1 - 2e-11 44.1 0.0 0.011 15.5 0.0 4.2 5 0 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.4 001287891.1_48629001_1 - 9.7e-07 29.2 0.1 0.011 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.4 001287891.1_48629001_1 - 1.3e-06 27.9 2.1 0.028 14.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.27 001287891.1_48629001_1 - 2.5e-06 27.8 0.4 0.0052 17.1 0.0 3.7 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.4 001287891.1_48629001_1 - 5.9e-06 25.9 0.3 0.014 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.14 001287891.1_48629001_1 - 1.5e-05 24.8 1.1 0.16 11.8 0.4 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.4 001287891.1_48629001_1 - 2.4e-05 24.7 0.0 0.18 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.4 001287891.1_48629001_1 - 4.3e-05 23.7 0.4 0.036 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.4 001287891.1_48629001_1 - 5.8e-05 23.1 0.2 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.4 001287891.1_48629001_1 - 0.00021 21.7 0.1 0.51 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.13 001287891.1_48629001_1 - 0.00023 21.0 1.0 0.033 14.0 0.0 3.3 3 0 0 3 3 3 1 NTPase SMC_N PF02463.17 001287891.1_48629001_1 - 0.00034 20.0 0.1 5.1 6.3 0.0 4.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.4 001287891.1_48629001_1 - 0.00045 19.9 1.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.4 001287891.1_48629001_1 - 0.0018 18.4 1.8 0.26 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.10 001287891.1_48629001_1 - 0.0023 17.1 0.2 0.089 12.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.10 001287891.1_48629001_1 - 0.006 15.8 0.7 0.037 13.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.10 001287891.1_48629001_1 - 0.0064 16.3 3.2 0.26 11.1 0.1 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.17 001287891.1_48629001_1 - 0.0093 15.4 4.8 0.15 11.5 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.4 001287891.1_48629001_1 - 0.015 14.9 0.8 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.21 001287891.1_48629001_1 - 0.016 15.1 0.1 8.5 6.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.13 001287891.1_48629001_1 - 0.021 13.6 0.0 3 6.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.4 001287891.1_48629001_1 - 0.03 14.6 2.7 0.42 10.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.20 001287891.1_48629001_1 - 0.034 14.4 0.0 9 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.12 001287891.1_48629001_1 - 0.04 13.8 2.8 0.19 11.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.7 001287891.1_48629001_1 - 0.074 12.7 1.6 9 5.9 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.4 001287891.1_48629001_1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.15 001287891.1_48629001_1 - 0.12 12.2 1.7 8.6 6.2 0.0 2.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.4 001287891.1_48629001_1 - 0.19 11.9 0.6 0.74 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.7 001287891.1_48629001_1 - 0.2 10.7 2.0 0.43 9.6 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.20 001287891.1_48629001_1 - 1.1 8.7 4.9 7.9 5.9 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Gp_dh_C PF02800.18 001288348.1_48623001_2 - 3.5e-72 241.0 0.0 4.9e-72 240.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001288348.1_48623001_2 - 1.9e-34 117.9 0.0 5.4e-34 116.4 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001288348.1_48623001_2 - 0.00064 19.7 0.0 0.0021 18.1 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.17 001288348.1_48623001_2 - 0.011 15.0 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Band_7 PF01145.23 001316904.1_48622001_1 - 4.7e-28 98.3 2.7 6.3e-28 97.8 2.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.4 001316904.1_48622001_1 - 0.019 14.6 0.7 0.035 13.7 0.2 1.7 2 0 0 2 2 2 0 SPFH domain-Band 7 family UQ_con PF00179.24 001288134.1_48622001_2 - 2.2e-53 179.6 0.0 2.6e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001288134.1_48622001_2 - 0.084 13.0 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain Aminotran_4 PF01063.17 001288351.1_48624001_1 - 4e-42 144.5 0.0 4.9e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glycos_transf_4 PF00953.19 001287892.1_48623001_1 - 1.2e-35 122.6 11.7 1.2e-35 122.6 11.7 2.8 2 1 1 3 3 3 1 Glycosyl transferase family 4 Pox_A14 PF05767.10 001287892.1_48623001_1 - 0.057 13.4 0.9 0.057 13.4 0.9 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Per1 PF04080.11 001288135.1_48623001_1 - 8.5e-90 300.8 9.9 1.1e-89 300.4 9.9 1.2 1 0 0 1 1 1 1 Per1-like MIP PF00230.18 001288136.1_48622001_1 - 8.9e-82 274.0 12.9 1e-81 273.8 12.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein UQ_con PF00179.24 001288686.1_48622001_1 - 3e-53 179.1 0.0 3.7e-53 178.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001288686.1_48622001_1 - 0.0032 17.6 0.0 0.0044 17.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.4 001288686.1_48622001_1 - 0.0056 16.3 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.11 001288686.1_48622001_1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain peroxidase PF00141.21 001288137.1_48622001_1 - 1.1e-45 156.0 0.0 1.7e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Ribosomal_L16 PF00252.16 001288688.1_48622001_2 - 8.9e-42 142.1 0.1 1.3e-41 141.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e potato_inhibit PF00280.16 001288353.1_48621001_1 - 3.8e-14 52.9 0.0 5.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Potato inhibitor I family Glyco_hydro_32N PF00251.18 001287894.1_48624001_1 - 1.1e-105 353.5 7.3 1.4e-105 353.1 7.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.10 001287894.1_48624001_1 - 1.3e-13 51.3 0.0 3.2e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Cofilin_ADF PF00241.18 001288689.1_48622001_1 - 9.1e-36 122.7 0.6 1.3e-35 122.2 0.6 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SRF-TF PF00319.16 001288355.1_48623001_3 - 6.3e-25 86.3 0.2 1.1e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001288355.1_48623001_3 - 2.9e-15 56.1 11.6 2.9e-15 56.1 11.6 2.4 2 1 1 3 3 3 1 K-box region ZapB PF06005.10 001288355.1_48623001_3 - 0.0063 16.8 1.7 0.0063 16.8 1.7 2.4 1 1 1 2 2 2 1 Cell division protein ZapB GIT_CC PF16559.3 001288355.1_48623001_3 - 0.02 14.8 1.0 0.05 13.5 1.0 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.19 001288355.1_48623001_3 - 0.068 13.1 0.5 0.068 13.1 0.5 3.3 3 0 0 3 3 3 0 bZIP transcription factor PfkB PF00294.22 001287895.1_48623001_1 - 4.1e-76 256.0 0.0 5.1e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CYYR1 PF10873.6 001288140.1_48624001_2 - 1.8 8.9 11.7 2.9 8.2 11.7 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 RRM_1 PF00076.20 001288140.1_48624001_3 - 8.1e-12 44.7 0.0 1.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.3 001288140.1_48624001_3 - 4e-07 30.6 0.1 8.3e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.3 001288140.1_48624001_3 - 0.011 15.8 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH PF00642.22 001288140.1_48624001_3 - 0.027 14.3 1.1 0.094 12.5 1.1 2.0 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_occluded PF16842.3 001288140.1_48624001_3 - 0.027 14.2 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif Globin PF00042.20 001288139.1_48622001_1 - 4e-19 69.1 0.4 5.6e-19 68.6 0.4 1.2 1 0 0 1 1 1 1 Globin ITAM_Cys-rich PF10538.7 001288139.1_48622001_3 - 0.095 12.3 1.0 0.2 11.3 1.0 1.6 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif MFS_2 PF13347.4 001288141.1_48624001_1 - 3.3e-15 55.4 15.0 1.4e-13 50.1 15.0 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein PUCC PF03209.13 001288141.1_48624001_1 - 1.9e-08 33.6 0.2 1.9e-08 33.6 0.2 2.1 2 0 0 2 2 2 1 PUCC protein Band_7 PF01145.23 001287897.1_48623001_2 - 3.5e-25 88.9 2.0 5.3e-25 88.3 2.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF1191 PF06697.10 001287897.1_48623001_2 - 0.048 12.7 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TCP PF03634.11 001288693.1_48623001_1 - 2.9e-45 154.5 9.8 4.4e-45 153.9 9.8 1.3 1 0 0 1 1 1 1 TCP family transcription factor DUF793 PF05633.9 001287899.1_48623001_1 - 1.1e-12 47.6 0.1 1e-05 24.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF793) DUF241 PF03087.12 001287899.1_48623001_1 - 6.6e-08 32.6 0.1 1.1e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 Arabidopsis protein of unknown function DUF677 PF05055.10 001287899.1_48623001_1 - 0.024 13.4 1.4 0.59 8.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF677) Hexapep PF00132.22 001288142.1_48623001_2 - 9e-14 50.4 9.8 8.1e-05 22.1 0.5 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.4 001288142.1_48623001_2 - 7.5e-06 25.5 2.5 0.00075 19.1 0.5 4.0 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Ribosomal_L4 PF00573.20 001288695.1_48623001_1 - 2.5e-40 138.1 0.1 4.2e-40 137.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.4 001288695.1_48623001_1 - 3.3e-30 103.8 4.7 3.3e-30 103.8 4.7 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain WD40 PF00400.30 001288360.1_48623001_2 - 3.2e-37 125.7 23.2 3e-09 37.2 0.6 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001288360.1_48623001_2 - 3.1e-16 59.3 0.2 6.8e-06 26.2 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001288360.1_48623001_2 - 2e-06 26.9 3.0 0.0062 15.4 0.0 4.0 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.4 001288360.1_48623001_2 - 1.1e-05 25.6 1.2 0.65 10.4 0.0 4.3 4 0 0 4 4 4 2 PQQ-like domain Nup160 PF11715.6 001288360.1_48623001_2 - 0.0012 17.4 5.4 1.4 7.3 0.2 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.4 001288360.1_48623001_2 - 0.0015 17.8 0.9 1.4 8.0 0.1 3.0 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.3 001288360.1_48623001_2 - 0.0074 15.5 0.0 0.74 8.9 0.0 2.6 3 0 0 3 3 3 1 WD40-like domain PALB2_WD40 PF16756.3 001288360.1_48623001_2 - 0.0091 14.8 2.1 0.088 11.6 0.2 2.6 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.14 001288360.1_48623001_2 - 0.021 13.3 0.2 1.2 7.5 0.1 2.7 1 1 1 3 3 3 0 Cytochrome D1 heme domain Frtz PF11768.6 001288360.1_48623001_2 - 0.024 12.8 0.0 0.63 8.2 0.0 2.5 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz RNase_PH PF01138.19 001288144.1_48623001_3 - 8.2e-20 71.5 0.9 1.8e-19 70.4 0.0 2.0 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.13 001288144.1_48623001_3 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RRM_1 PF00076.20 001287901.1_48623001_2 - 1.2e-20 72.9 0.0 2e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001287901.1_48623001_2 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001287901.1_48623001_2 - 0.022 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_L6 PF00347.21 001287900.1_48622001_2 - 1.9e-24 86.0 4.1 1.1e-12 48.3 0.4 2.4 2 1 0 2 2 2 2 Ribosomal protein L6 Arf PF00025.19 001287903.1_48622001_3 - 1.3e-79 265.6 0.1 1.5e-79 265.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.11 001287903.1_48622001_3 - 2.2e-13 50.3 0.0 3.5e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.8 001287903.1_48622001_3 - 2.8e-13 49.5 0.0 3.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.18 001287903.1_48622001_3 - 3.5e-12 46.0 0.8 2.3e-08 33.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.20 001287903.1_48622001_3 - 4.3e-12 45.8 0.0 5.1e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.10 001287903.1_48622001_3 - 7.3e-10 38.5 0.0 9.3e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001287903.1_48622001_3 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 001287903.1_48622001_3 - 0.012 14.8 0.3 0.026 13.7 0.1 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase adh_short_C2 PF13561.4 001288361.1_48622001_1 - 1.6e-56 191.3 0.0 2e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001288361.1_48622001_1 - 4.9e-54 182.6 0.1 6e-54 182.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001288361.1_48622001_1 - 2.4e-14 53.5 0.0 3.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001288361.1_48622001_1 - 0.0034 16.8 0.1 0.024 14.0 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.17 001288361.1_48622001_1 - 0.098 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PI-PLC-X PF00388.17 001288146.1_48624001_1 - 2.6e-48 163.2 0.0 4.4e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.17 001288146.1_48624001_1 - 3.6e-28 98.1 0.0 6.9e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.28 001288146.1_48624001_1 - 1.9e-12 47.2 0.0 3.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.9 001288146.1_48624001_1 - 7.6e-10 39.0 0.2 2.2e-09 37.6 0.0 1.8 2 0 0 2 2 1 1 Phosphoinositide-specific phospholipase C, efhand-like Pox_Ag35 PF03286.12 001288146.1_48624001_1 - 0.0073 16.0 8.6 0.012 15.2 8.6 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DNA_pol_phi PF04931.11 001288146.1_48624001_1 - 0.019 13.0 7.3 0.029 12.4 7.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi ATHILA PF03078.13 001288146.1_48624001_1 - 0.023 13.4 2.1 0.035 12.8 2.1 1.3 1 0 0 1 1 1 0 ATHILA ORF-1 family PTPRCAP PF15713.3 001288146.1_48624001_1 - 0.038 14.1 7.3 0.068 13.3 7.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PI3K_C2 PF00792.22 001288146.1_48624001_1 - 0.041 13.8 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 FAM176 PF14851.4 001288146.1_48624001_1 - 0.043 13.4 4.5 0.086 12.4 4.5 1.4 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.10 001288146.1_48624001_1 - 0.045 13.4 4.1 0.071 12.8 4.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sporozoite_P67 PF05642.9 001288146.1_48624001_1 - 0.1 10.5 2.8 0.14 10.1 2.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.9 001288146.1_48624001_1 - 0.12 12.2 7.2 0.23 11.4 7.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.12 001288146.1_48624001_1 - 0.19 9.9 5.4 0.33 9.1 5.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4484 PF14831.4 001288146.1_48624001_1 - 0.36 10.7 4.9 6.4 6.6 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DUF1510 PF07423.9 001288146.1_48624001_1 - 1.1 8.5 10.0 1.8 7.9 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Astro_capsid_p PF12226.6 001288146.1_48624001_1 - 1.2 8.1 9.8 2.2 7.2 9.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PBP1_TM PF14812.4 001288146.1_48624001_1 - 2.4 8.5 12.3 5.5 7.4 12.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.8 001288146.1_48624001_1 - 2.5 8.4 13.5 4.8 7.5 13.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain S-antigen PF05756.9 001288146.1_48624001_1 - 2.5 8.3 9.2 1.6 8.8 6.8 1.9 2 0 0 2 2 1 0 S-antigen protein DUF2457 PF10446.7 001288146.1_48624001_1 - 2.7 6.9 14.0 4 6.4 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HSP90 PF00183.16 001287904.1_48625001_2 - 3.2e-232 771.8 32.2 4e-232 771.5 32.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.24 001287904.1_48625001_2 - 1.4e-14 54.4 0.1 3e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001287904.1_48625001_2 - 2e-10 40.5 0.1 5e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4976 PF16347.3 001287904.1_48625001_2 - 0.077 13.1 0.1 0.077 13.1 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4976) LOH1CR12 PF10158.7 001287904.1_48625001_2 - 0.091 12.7 0.6 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Tumour suppressor protein PTPRCAP PF15713.3 001287904.1_48625001_2 - 0.13 12.4 6.1 0.35 11.0 6.1 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Arf PF00025.19 001287905.1_48622001_3 - 1.6e-79 265.2 0.1 2e-79 265.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001287905.1_48622001_3 - 2.1e-13 50.0 0.0 2.7e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.11 001287905.1_48622001_3 - 2.3e-13 50.3 0.0 3.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.18 001287905.1_48622001_3 - 3.1e-12 46.2 0.9 2.1e-08 33.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.20 001287905.1_48622001_3 - 3.2e-12 46.2 0.0 3.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.10 001287905.1_48622001_3 - 6.2e-10 38.7 0.0 7.8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001287905.1_48622001_3 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 001287905.1_48622001_3 - 0.013 14.7 0.4 0.025 13.8 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase WRKY PF03106.13 001287907.1_48624001_1 - 5.2e-52 173.9 15.6 1.1e-25 89.6 3.8 2.6 2 0 0 2 2 2 2 WRKY DNA -binding domain FAR1 PF03101.13 001287907.1_48624001_1 - 0.002 18.7 1.8 0.24 12.0 0.0 2.6 2 0 0 2 2 2 2 FAR1 DNA-binding domain FLYWCH PF04500.14 001287907.1_48624001_1 - 0.059 13.4 4.1 0.46 10.5 0.4 2.5 2 0 0 2 2 2 0 FLYWCH zinc finger domain Cys_Met_Meta_PP PF01053.18 001288149.1_48624001_1 - 2.8e-145 483.5 0.0 3.3e-145 483.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.19 001288149.1_48624001_1 - 2.2e-06 27.0 0.0 3.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.17 001288149.1_48624001_1 - 6.6e-06 25.2 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.15 001288149.1_48624001_1 - 2.8e-05 23.5 0.0 4.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.14 001288149.1_48624001_1 - 0.0057 15.4 0.0 0.0087 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.19 001288149.1_48624001_1 - 0.087 12.0 0.0 0.24 10.5 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase FliJ PF02050.14 001288149.1_48624001_2 - 0.17 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein Ank_2 PF12796.5 001287908.1_48625001_3 - 9e-38 128.6 4.1 1.1e-10 41.9 0.5 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.28 001287908.1_48625001_3 - 3.7e-35 118.7 11.5 1.6e-08 34.5 0.3 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.4 001287908.1_48625001_3 - 7.2e-31 106.0 7.2 7.1e-12 45.5 0.1 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.4 001287908.1_48625001_3 - 8.2e-30 102.3 13.7 4.8e-07 29.8 0.3 5.6 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.4 001287908.1_48625001_3 - 4.9e-26 87.8 9.0 0.00045 20.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat zf-C3HC4_3 PF13920.4 001287908.1_48625001_3 - 0.0018 17.9 9.6 0.0054 16.4 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001287908.1_48625001_3 - 0.06 13.5 12.2 0.21 11.7 12.2 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.23 001287908.1_48625001_3 - 0.083 12.6 12.0 0.23 11.2 12.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pentapeptide PF00805.20 001288150.1_48622001_1 - 5.9e-21 73.6 7.1 1.7e-10 40.2 0.7 2.9 1 1 2 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.4 001288150.1_48622001_1 - 2e-17 62.9 6.1 3.4e-10 39.8 0.7 2.3 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.4 001288150.1_48622001_1 - 1.5e-12 47.4 0.7 8.6e-09 35.3 1.0 2.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DUF99 PF01949.14 001288150.1_48622001_1 - 0.17 11.2 0.2 1.3 8.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF99 GAGA_bind PF06217.10 001288700.1_48623001_3 - 4.3e-114 381.6 0.1 5.4e-114 381.3 0.1 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family Ras PF00071.20 001287909.1_48622001_1 - 1.3e-56 190.6 0.1 1.6e-56 190.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001287909.1_48622001_1 - 1e-32 112.8 0.0 1.4e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001287909.1_48622001_1 - 3.6e-14 52.5 0.0 4.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001287909.1_48622001_1 - 1.6e-07 31.3 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001287909.1_48622001_1 - 2.1e-06 27.3 0.0 4.1e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.10 001287909.1_48622001_1 - 3.6e-06 26.4 0.0 4.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.14 001287909.1_48622001_1 - 0.0007 19.4 0.0 0.0038 17.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.4 001287909.1_48622001_1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.15 001287909.1_48622001_1 - 0.0061 16.2 0.1 0.19 11.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.8 001287909.1_48622001_1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.9 001287909.1_48622001_1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.7 001287909.1_48622001_1 - 0.02 14.5 0.1 0.24 11.0 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.16 001287909.1_48622001_1 - 0.021 14.0 0.1 0.041 13.0 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_22 PF13401.4 001287909.1_48622001_1 - 0.021 15.0 0.0 0.034 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.4 001287909.1_48622001_1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.16 001287909.1_48622001_1 - 0.054 13.3 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MCM PF00493.21 001287909.1_48622001_1 - 0.066 12.2 0.1 0.09 11.7 0.1 1.1 1 0 0 1 1 1 0 MCM2/3/5 family cobW PF02492.17 001287909.1_48622001_1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.20 001287909.1_48622001_1 - 0.079 13.2 0.0 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.13 001287909.1_48622001_1 - 0.098 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 NTPase DAP3 PF10236.7 001287909.1_48622001_1 - 0.12 11.4 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Uricase PF01014.16 001288366.1_48623001_1 - 4.2e-57 192.0 0.0 2.1e-34 118.6 0.0 2.1 2 0 0 2 2 2 2 Uricase DUF4202 PF13875.4 001288366.1_48623001_1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) MIP PF00230.18 001288152.1_48622001_1 - 1.3e-20 73.9 12.7 1.6e-20 73.7 12.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein VIT1 PF01988.17 001288152.1_48622001_1 - 0.14 11.9 4.9 0.24 11.1 4.9 1.4 1 0 0 1 1 1 0 VIT family Ank_2 PF12796.5 001288365.1_48624001_1 - 1.2e-40 137.9 3.7 1.6e-13 50.9 0.1 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001288365.1_48624001_1 - 2.1e-40 136.4 0.2 2e-10 40.8 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.4 001288365.1_48624001_1 - 7.4e-34 111.8 0.8 1.1e-05 25.2 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.28 001288365.1_48624001_1 - 1.6e-26 91.4 5.7 6.3e-05 23.1 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.4 001288365.1_48624001_1 - 1.9e-26 91.5 1.5 3.6e-06 27.1 0.0 5.8 2 1 4 6 6 6 6 Ankyrin repeats (many copies) TPR_2 PF07719.15 001288365.1_48624001_1 - 3.2e-11 42.3 3.5 0.0061 16.5 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.26 001288365.1_48624001_1 - 7.1e-11 41.3 0.9 0.00091 18.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.4 001288365.1_48624001_1 - 1.6e-06 27.6 0.0 0.00036 20.0 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.4 001288365.1_48624001_1 - 5.3e-05 23.0 0.1 1.6 9.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.4 001288365.1_48624001_1 - 0.002 18.2 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.4 001288365.1_48624001_1 - 0.0062 16.9 0.1 0.081 13.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.4 001288365.1_48624001_1 - 0.007 17.0 5.1 3.6 8.5 0.1 3.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.4 001288365.1_48624001_1 - 0.016 15.8 6.4 0.044 14.4 0.4 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.4 001288365.1_48624001_1 - 0.055 13.5 2.6 0.1 12.6 0.8 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.4 001288365.1_48624001_1 - 0.13 12.3 0.8 1.2 9.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FBPase PF00316.18 001287911.1_48623001_2 - 2.9e-55 186.6 0.5 4.3e-55 186.0 0.5 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain PUA PF01472.18 001287911.1_48623001_2 - 0.079 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 PUA domain Remorin_C PF03763.11 001288368.1_48622001_1 - 9.8e-30 102.5 22.3 1.7e-29 101.7 22.3 1.4 1 0 0 1 1 1 1 Remorin, C-terminal region Remorin_N PF03766.11 001288368.1_48622001_1 - 2.3e-11 43.4 9.4 2.3e-11 43.4 9.4 2.7 3 0 0 3 3 3 1 Remorin, N-terminal region HMG-CoA_red PF00368.16 001288155.1_48624001_1 - 3.2e-143 477.1 1.2 3.8e-143 476.8 1.2 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase PI-PLC-X PF00388.17 001288369.1_48624001_2 - 1.2e-50 170.8 0.0 2.4e-50 169.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.17 001288369.1_48624001_2 - 5.4e-29 100.8 0.0 1.7e-28 99.2 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.28 001288369.1_48624001_2 - 1.6e-12 47.5 0.0 3.1e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.9 001288369.1_48624001_2 - 1.4e-06 28.5 0.1 3.2e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like DUF2267 PF10025.7 001288369.1_48624001_2 - 0.2 11.8 0.1 0.49 10.6 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) BTB PF00651.29 001288370.1_48627001_1 - 1.3e-14 54.2 0.9 9.6e-07 28.9 0.0 3.4 3 0 0 3 3 3 2 BTB/POZ domain DUF4922 PF16269.3 001288371.1_48624001_2 - 1.3e-06 28.1 0.0 4.1e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) KNOX2 PF03791.11 001291923.1_48622001_1 - 5.3e-10 38.7 1.1 9e-10 38.0 1.1 1.4 1 0 0 1 1 1 1 KNOX2 domain KNOX1 PF03790.11 001291923.1_48622001_1 - 1e-06 28.2 0.1 2.6e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 KNOX1 domain Trypsin PF00089.24 001291923.1_48622001_1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Trypsin BAH PF01426.16 001288372.1_48623001_3 - 5.7e-23 80.9 0.0 8.6e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 BAH domain PHD PF00628.27 001288372.1_48623001_3 - 3.1e-10 39.7 7.4 3.1e-10 39.7 7.4 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.4 001288372.1_48623001_3 - 0.0025 17.2 0.6 0.0056 16.1 0.6 1.6 1 0 0 1 1 1 1 PHD-finger Polyketide_cyc2 PF10604.7 001297628.1_48622001_1 - 4.5e-22 78.7 0.0 5.3e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1857 PF08982.9 001297628.1_48622001_1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Polyketide_cyc PF03364.18 001297628.1_48622001_1 - 0.038 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Bet_v_1 PF00407.17 001297628.1_48622001_1 - 0.086 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family PA PF02225.20 001288373.1_48625001_2 - 2.6e-10 40.1 0.0 6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 PA domain cEGF PF12662.5 001288373.1_48625001_2 - 8.8e-06 25.4 4.4 8.8e-06 25.4 4.4 3.9 3 0 0 3 3 3 1 Complement Clr-like EGF-like EGF_CA PF07645.13 001288373.1_48625001_2 - 0.0014 18.6 14.0 0.0014 18.6 14.0 4.9 3 1 2 5 5 5 1 Calcium-binding EGF domain EGF_3 PF12947.5 001288373.1_48625001_2 - 8.7 6.5 40.0 13 5.9 7.5 5.9 2 1 1 3 3 3 0 EGF domain Tubulin PF00091.23 001288157.1_48624001_3 - 4.9e-68 229.1 0.0 6.8e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001288157.1_48624001_3 - 3.4e-46 156.4 0.0 6.3e-46 155.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001288157.1_48624001_3 - 0.0094 15.5 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain p450 PF00067.20 001287915.1_48624001_3 - 9.2e-74 248.7 0.0 1.3e-73 248.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ARD PF03079.12 001287916.1_48622001_3 - 2.7e-63 212.7 0.1 3.2e-63 212.5 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.9 001287916.1_48622001_3 - 5.4e-07 29.1 0.4 7.8e-06 25.4 0.0 2.2 1 1 1 2 2 2 1 Cupin domain AraC_binding PF02311.17 001287916.1_48622001_3 - 0.008 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.20 001287916.1_48622001_3 - 0.087 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Ribosomal_L7Ae PF01248.24 001288376.1_48623001_3 - 3.7e-24 84.1 0.4 7.4e-24 83.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.10 001288376.1_48623001_3 - 0.035 13.0 0.2 0.049 12.5 0.2 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Pkinase_Tyr PF07714.15 001287917.1_48624001_3 - 4.4e-47 160.4 0.0 6.7e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001287917.1_48624001_3 - 4.4e-46 157.2 0.0 7.1e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.4 001287917.1_48624001_3 - 0.092 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.21 001287917.1_48624001_3 - 0.1 12.3 0.1 3.3 7.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family WRKY PF03106.13 001287918.1_48622001_2 - 1.8e-26 92.1 1.1 4.1e-26 91.0 1.1 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain SNAP PF14938.4 001288377.1_48623001_3 - 7.7e-28 97.6 12.2 9.7e-28 97.3 12.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.4 001288377.1_48623001_3 - 9.2e-07 28.9 11.1 0.031 14.4 1.7 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.15 001288377.1_48623001_3 - 0.00019 21.2 15.6 2.9 8.1 1.2 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.4 001288377.1_48623001_3 - 0.00039 20.9 7.8 8.7 7.3 0.4 5.2 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.4 001288377.1_48623001_3 - 0.003 17.9 2.9 0.003 17.9 2.9 3.0 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.4 001288377.1_48623001_3 - 0.081 13.1 8.9 3.2 8.1 0.9 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.4 001288377.1_48623001_3 - 0.086 12.8 11.8 4.3 7.5 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001288377.1_48623001_3 - 0.095 12.8 0.4 0.095 12.8 0.4 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.3 001288377.1_48623001_3 - 0.22 11.4 4.6 0.24 11.3 1.8 2.1 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_1 PF00515.26 001288377.1_48623001_3 - 0.35 10.6 19.5 3.4 7.5 0.8 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.4 001288377.1_48623001_3 - 0.68 10.6 11.0 2 9.1 3.9 3.6 3 2 0 3 3 3 0 Tetratricopeptide repeat NSF PF02071.18 001288377.1_48623001_3 - 1.9 9.5 24.3 32 5.8 0.9 7.8 8 0 0 8 8 8 0 Aromatic-di-Alanine (AdAR) repeat MIT PF04212.16 001288377.1_48623001_3 - 9.5 6.3 17.2 7 6.7 3.9 5.0 3 1 2 5 5 5 0 MIT (microtubule interacting and transport) domain Ldh_1_N PF00056.21 001288160.1_48623001_2 - 1.3e-43 148.3 0.1 2e-43 147.7 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001288160.1_48623001_2 - 1.3e-25 90.1 0.0 2.1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Pyr_redox_2 PF07992.12 001288160.1_48623001_2 - 0.044 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S3_C PF00189.18 001288378.1_48622001_1 - 2.5e-25 88.6 0.5 8.3e-25 87.0 0.7 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.15 001288378.1_48622001_1 - 1.6e-12 46.9 0.7 2.5e-12 46.3 0.7 1.3 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.3 001288378.1_48622001_1 - 0.056 13.1 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus UN_NPL4 PF11543.6 001288378.1_48622001_1 - 0.15 12.4 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 E1-E2_ATPase PF00122.18 001287919.1_48627001_1 - 1.7e-60 204.0 0.7 1.7e-60 204.0 0.7 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.24 001287919.1_48627001_1 - 1.7e-18 67.5 0.0 4.4e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 001287919.1_48627001_1 - 3.1e-15 55.5 0.0 8e-15 54.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.4 001287919.1_48627001_1 - 0.00027 20.8 0.0 0.00088 19.2 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.10 001287919.1_48627001_1 - 0.0014 18.3 0.1 0.0036 16.9 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MPC PF03650.11 001287919.1_48627001_1 - 0.85 9.6 4.1 6.4 6.8 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0041) Phytochelatin_C PF09328.8 001288379.1_48625001_2 - 1.9e-122 407.6 0.6 2.9e-122 406.9 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1984) Phytochelatin PF05023.12 001288379.1_48625001_2 - 3.3e-88 294.3 0.0 4.6e-88 293.9 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.4 001288379.1_48625001_2 - 0.0083 16.6 0.2 0.25 11.7 0.0 2.8 3 0 0 3 3 3 1 Peptidase_C39 like family cobW PF02492.17 001287920.1_48622001_1 - 3.7e-32 111.2 0.0 4.7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.14 001287920.1_48622001_1 - 0.00013 21.0 1.1 0.0049 15.8 1.1 2.1 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.21 001287920.1_48622001_1 - 0.058 13.4 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase TIP49 PF06068.11 001287920.1_48622001_1 - 0.064 12.1 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.4 001287920.1_48622001_1 - 0.089 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.13 001287920.1_48622001_1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.27 001287920.1_48622001_1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SUI1 PF01253.20 001287921.1_48622001_2 - 6.4e-24 84.2 1.5 1e-23 83.5 1.5 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ribosomal_S8e PF01201.20 001287922.1_48622001_1 - 1.3e-59 200.1 1.8 1.9e-59 199.6 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e TFIID_20kDa PF03847.11 001288381.1_48625001_2 - 1.2e-32 112.1 0.6 2.3e-32 111.2 0.6 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.22 001288381.1_48625001_2 - 0.00018 21.8 0.0 0.00018 21.8 0.0 4.0 5 0 0 5 5 5 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001288381.1_48625001_2 - 0.0028 17.8 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UDPGT PF00201.16 001287923.1_48623001_1 - 1.7e-26 92.9 0.1 3.1e-26 92.1 0.1 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001287923.1_48623001_1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Myb_DNA-binding PF00249.29 001288382.1_48622001_1 - 1.5e-32 111.3 2.0 2.6e-16 59.4 1.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001288382.1_48622001_1 - 6.1e-19 67.9 0.1 2.8e-10 40.1 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Ribosomal_S4e PF00900.18 001288164.1_48623001_3 - 2.3e-35 120.2 0.2 5.9e-35 118.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.3 001288164.1_48623001_3 - 3.6e-26 90.4 0.0 7.6e-26 89.4 0.0 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.10 001288164.1_48623001_3 - 1e-19 70.2 6.1 2.6e-19 68.9 6.1 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.27 001288164.1_48623001_3 - 3.5e-07 29.8 2.6 2.1e-06 27.4 2.7 2.1 2 0 0 2 2 2 1 KOW motif S4 PF01479.23 001288164.1_48623001_3 - 3.4e-06 26.5 0.1 7.2e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 S4 domain Sipho_tail PF05709.9 001288164.1_48623001_3 - 0.0062 15.9 0.2 2.4 7.4 0.0 2.2 2 0 0 2 2 2 2 Phage tail protein WD40 PF00400.30 001288383.1_48623001_3 - 3.5e-25 87.6 15.5 0.00032 21.3 0.6 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001288383.1_48623001_3 - 1.4e-08 34.8 8.9 0.018 15.2 0.2 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Big_2 PF02368.16 001288383.1_48623001_3 - 0.018 14.8 1.0 4.6 7.1 0.4 2.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) IKI3 PF04762.10 001288383.1_48623001_3 - 0.046 11.6 0.5 1.1 7.0 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PBP PF01161.18 001287924.1_48622001_1 - 7.5e-17 61.7 0.0 8.7e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RRM_1 PF00076.20 001288165.1_48623001_2 - 1.8e-43 146.0 0.0 1.1e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001288165.1_48623001_2 - 8.5e-06 25.7 0.1 0.2 11.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.4 001288165.1_48623001_2 - 0.0018 17.7 0.0 0.3 10.6 0.0 2.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TC1 PF15063.4 001288165.1_48623001_2 - 0.075 12.8 0.0 7.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Thyroid cancer protein 1 Thioredoxin PF00085.18 001288384.1_48622001_2 - 1.4e-32 111.6 0.5 1.9e-32 111.2 0.5 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.4 001288384.1_48622001_2 - 4.1e-05 23.9 0.3 0.00092 19.5 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.4 001288384.1_48622001_2 - 0.00014 21.5 0.1 0.00017 21.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.8 001288384.1_48622001_2 - 0.0002 21.0 0.4 0.016 14.7 0.0 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_8 PF13905.4 001288384.1_48622001_2 - 0.00021 21.4 0.0 0.00072 19.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.4 001288384.1_48622001_2 - 0.00047 20.2 0.1 0.00077 19.5 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.19 001288384.1_48622001_2 - 0.018 14.8 0.1 0.035 13.9 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family RRM_1 PF00076.20 001288385.1_48623001_2 - 1.4e-23 82.4 0.0 2.2e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001288385.1_48623001_2 - 0.00069 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.6 001288385.1_48623001_2 - 0.0086 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Limkain b1 RRM_5 PF13893.4 001288385.1_48623001_2 - 0.056 12.9 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.23 001287926.1_48624001_2 - 6.1e-64 215.8 0.0 7.4e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001287926.1_48624001_2 - 4.2e-25 88.4 0.0 5.6e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001287926.1_48624001_2 - 0.00049 19.4 0.0 0.3 10.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.18 001287926.1_48624001_2 - 0.001 18.6 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.21 001287926.1_48624001_2 - 0.0082 16.0 0.1 0.028 14.2 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L16 PF00252.16 001288167.1_48622001_3 - 1.3e-41 141.6 0.1 1.7e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Hexokinase_2 PF03727.14 001288386.1_48624001_3 - 3.9e-77 258.8 0.0 5e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.19 001288386.1_48624001_3 - 2.3e-61 207.1 0.0 3.1e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Myb_DNA-binding PF00249.29 001288387.1_48623001_1 - 1.2e-31 108.5 2.5 5.5e-15 55.1 0.5 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001288387.1_48623001_1 - 1.2e-19 70.2 0.9 3.4e-11 43.1 0.1 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Cpn60_TCP1 PF00118.22 001288168.1_48625001_2 - 4.8e-104 348.6 19.6 7.9e-104 347.9 19.6 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family bHLH-MYC_N PF14215.4 001288169.1_48625001_1 - 1.6e-53 181.4 0.0 4.2e-53 180.0 0.0 1.8 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 001288169.1_48625001_1 - 4.9e-12 45.5 0.1 1.3e-11 44.1 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CENP-B_dimeris PF09026.8 001288169.1_48625001_1 - 0.05 13.9 11.4 0.12 12.6 11.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.10 001288169.1_48625001_1 - 1.7 7.8 7.1 3.2 6.9 7.1 1.4 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.9 001288169.1_48625001_1 - 3.6 5.4 9.1 7.2 4.4 4.4 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Pkinase PF00069.23 001288389.1_48623001_1 - 9.1e-72 241.5 0.0 1.2e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288389.1_48623001_1 - 1.1e-32 113.2 0.0 1.9e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001288389.1_48623001_1 - 0.035 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001288389.1_48623001_1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mo25 PF08569.9 001288389.1_48623001_1 - 0.18 11.0 0.1 1.1 8.4 0.1 1.9 2 0 0 2 2 2 0 Mo25-like Ribosomal_L30 PF00327.18 001287928.1_48623001_3 - 1.3e-15 56.9 0.4 4.1e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.10 001287928.1_48623001_3 - 2.5e-11 43.5 7.3 4.8e-11 42.6 7.3 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain PLDc_3 PF13918.4 001287928.1_48623001_3 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PLD-like domain HAGH_C PF16123.3 001288170.1_48622001_1 - 1.2e-20 73.7 0.0 1.9e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.25 001288170.1_48622001_1 - 6.1e-13 49.1 4.4 6.4e-12 45.8 4.4 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.5 001288170.1_48622001_1 - 0.00078 18.9 0.3 0.0017 17.8 0.3 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.4 001288170.1_48622001_1 - 0.027 14.3 0.3 0.041 13.6 0.3 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain LPMO_10 PF03067.13 001288170.1_48622001_1 - 0.19 12.2 0.5 12 6.3 0.1 2.4 2 1 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Ribosomal_S8e PF01201.20 001288171.1_48622001_2 - 3.1e-56 189.2 3.3 3.8e-56 188.9 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e FAD_binding_4 PF01565.21 001288391.1_48624001_1 - 1.2e-26 93.0 0.1 1.9e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.12 001288391.1_48624001_1 - 6.4e-16 58.8 4.0 9.9e-15 54.9 4.0 2.2 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase GDI PF00996.16 001287931.1_48624001_3 - 4.5e-232 770.0 0.1 5.6e-232 769.7 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor TypeIII_RM_meth PF12564.6 001287931.1_48624001_3 - 0.026 14.5 0.0 0.08 12.9 0.0 1.8 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit Pkinase PF00069.23 001288392.1_48623001_2 - 2e-73 246.9 0.0 2.7e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288392.1_48623001_2 - 3.2e-33 115.0 0.0 4.7e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001288392.1_48623001_2 - 1.6e-05 24.2 0.0 3.7e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.12 001288392.1_48623001_2 - 0.00021 20.6 0.1 0.00034 19.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Tom22 PF04281.11 001288392.1_48623001_2 - 0.19 11.4 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Mito_carr PF00153.25 001288173.1_48624001_1 - 3.6e-78 257.5 3.2 1.3e-25 89.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.18 001287932.1_48627001_3 - 1.4e-60 204.3 8.5 2.9e-60 203.2 0.7 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.24 001287932.1_48627001_3 - 1.6e-18 67.7 0.1 3.5e-18 66.5 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 001287932.1_48627001_3 - 2.7e-13 49.2 0.1 6.8e-13 47.9 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.10 001287932.1_48627001_3 - 0.00042 20.0 0.0 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.4 001287932.1_48627001_3 - 0.0025 17.7 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) dCMP_cyt_deam_1 PF00383.21 001287933.1_48622001_1 - 3e-23 81.5 2.3 4.6e-23 80.9 2.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.4 001287933.1_48622001_1 - 7.5e-20 71.0 0.8 1.1e-19 70.4 0.8 1.3 1 0 0 1 1 1 1 MafB19-like deaminase FAM24 PF15193.4 001287933.1_48622001_1 - 0.29 11.7 2.5 0.62 10.7 2.5 1.5 1 0 0 1 1 1 0 FAM24 family Glutaredoxin PF00462.22 001288175.1_48622001_1 - 1.8e-21 76.0 0.0 2.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.12 001288175.1_48622001_1 - 0.0053 17.0 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.4 001288175.1_48622001_1 - 0.036 14.3 0.0 0.072 13.3 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.18 001288175.1_48622001_1 - 0.044 13.6 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.4 001288175.1_48622001_1 - 0.045 14.1 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Pkinase PF00069.23 001288393.1_48624001_1 - 2.4e-75 253.1 0.0 3.9e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001288393.1_48624001_1 - 2.3e-32 108.0 3.8 1.1e-08 33.9 0.1 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.15 001288393.1_48624001_1 - 1.4e-31 109.6 0.0 2e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001288393.1_48624001_1 - 1.2e-28 99.3 1.0 1.2e-13 51.2 0.6 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001288393.1_48624001_1 - 9.2e-24 81.7 1.4 2e-06 26.9 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001288393.1_48624001_1 - 5.4e-23 78.8 2.1 5e-06 25.9 0.2 5.1 4 1 1 5 5 4 4 EF-hand domain EF-hand_8 PF13833.4 001288393.1_48624001_1 - 1.1e-21 76.2 3.9 8.8e-10 38.1 0.4 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.5 001288393.1_48624001_1 - 7.2e-08 32.2 0.2 0.016 15.0 0.0 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001288393.1_48624001_1 - 2.8e-06 27.5 0.0 0.055 13.7 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.12 001288393.1_48624001_1 - 1.6e-05 24.2 0.2 4.2e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.4 001288393.1_48624001_1 - 5.2e-05 23.4 0.0 0.062 13.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Kinase-like PF14531.4 001288393.1_48624001_1 - 0.00045 19.5 0.0 0.0043 16.3 0.0 2.1 1 1 0 2 2 2 1 Kinase-like EF-hand_11 PF08976.9 001288393.1_48624001_1 - 0.00086 20.0 0.0 0.14 12.9 0.0 2.5 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.8 001288393.1_48624001_1 - 0.019 14.9 0.0 7.5 6.6 0.0 2.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand APH PF01636.21 001288393.1_48624001_1 - 0.09 12.6 0.0 6.6 6.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RRM_1 PF00076.20 001288177.1_48622001_1 - 6.1e-09 35.5 0.0 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001288177.1_48622001_1 - 4.8e-05 23.1 0.0 9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L18A PF01775.15 001288178.1_48622001_3 - 5.3e-54 181.4 4.5 8.6e-54 180.7 4.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ribosomal_S7e PF01251.16 001288180.1_48622001_3 - 4e-80 267.8 2.8 5.6e-80 267.3 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S7e NB-ARC PF00931.20 001287936.1_48625001_1 - 3.6e-40 137.7 0.1 1.1e-39 136.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain RPW8 PF05659.9 001287936.1_48625001_1 - 2.5e-14 53.0 0.3 5.1e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 LRR_8 PF13855.4 001287936.1_48625001_1 - 2.8e-05 23.7 1.4 1.3 8.7 0.0 4.3 3 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.5 001287936.1_48625001_1 - 0.00036 20.7 9.6 0.024 14.9 0.0 5.5 1 1 5 6 6 6 2 Leucine Rich repeats (2 copies) AAA_22 PF13401.4 001287936.1_48625001_1 - 0.00079 19.6 0.0 0.003 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.10 001287936.1_48625001_1 - 0.0046 16.8 0.1 0.013 15.3 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.4 001287936.1_48625001_1 - 0.008 16.6 0.1 0.053 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.4 001287936.1_48625001_1 - 0.01 15.9 0.3 0.048 13.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA PF00004.27 001287936.1_48625001_1 - 0.082 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.16 001287936.1_48625001_1 - 0.13 12.0 0.1 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Arf PF00025.19 001287938.1_48622001_1 - 4.6e-65 218.2 0.0 6e-65 217.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.18 001287938.1_48622001_1 - 1.4e-11 44.0 0.1 7.6e-08 31.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.11 001287938.1_48622001_1 - 1.4e-08 34.9 0.2 3.2e-08 33.7 0.0 1.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.8 001287938.1_48622001_1 - 1.7e-08 33.9 0.0 2.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001287938.1_48622001_1 - 7.4e-07 29.1 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.20 001287938.1_48622001_1 - 2.2e-06 27.2 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.10 001287938.1_48622001_1 - 0.0013 18.0 0.0 0.005 16.1 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.7 001287938.1_48622001_1 - 0.0062 16.2 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation S4 PF01479.23 001287939.1_48622001_1 - 2.7e-11 42.8 1.4 7.2e-11 41.5 1.4 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.17 001287939.1_48622001_1 - 1.1e-07 32.6 1.7 4.2e-07 30.7 1.2 2.3 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain KNOX2 PF03791.11 001288396.1_48622001_2 - 5.1e-23 80.4 1.1 7.9e-23 79.8 0.0 1.9 2 0 0 2 2 2 1 KNOX2 domain KNOX1 PF03790.11 001288396.1_48622001_2 - 2.4e-18 65.5 0.0 4.6e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 KNOX1 domain Homeobox_KN PF05920.9 001288396.1_48622001_2 - 2.8e-17 62.2 5.2 8.3e-17 60.7 5.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain ELK PF03789.11 001288396.1_48622001_2 - 1e-10 41.2 6.2 2.1e-10 40.2 6.2 1.6 1 0 0 1 1 1 1 ELK domain Homeobox PF00046.27 001288396.1_48622001_2 - 2.4e-07 30.3 1.6 8.8e-07 28.5 1.6 2.0 1 0 0 1 1 1 1 Homeobox domain PPDK_N PF01326.17 001287941.1_48629001_3 - 1.3e-31 110.0 0.0 8.7e-31 107.2 0.0 2.2 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.17 001287941.1_48629001_3 - 6.3e-17 61.1 0.1 1.4e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1990 PF09348.8 001288183.1_48623001_1 - 4e-42 143.7 0.0 5.4e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) Ribosomal_S17e PF00833.16 001287942.1_48622001_3 - 2.5e-58 195.2 1.2 3.1e-58 194.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal S17 Glyco_hydro_32N PF00251.18 001288398.1_48624001_1 - 8.1e-109 363.7 7.3 1.1e-108 363.3 7.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.10 001288398.1_48624001_1 - 1.3e-16 61.0 0.1 4.5e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Frigida PF07899.9 001287943.1_48624001_2 - 2.9e-113 377.8 0.9 2.9e-113 377.8 0.9 2.1 2 0 0 2 2 2 1 Frigida-like protein Lant_dehydr_C PF14028.4 001287943.1_48624001_2 - 0.13 11.6 2.0 0.27 10.6 2.0 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term CENP-Q PF13094.4 001287943.1_48624001_2 - 0.25 11.4 8.4 0.67 10.0 4.0 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4164 PF13747.4 001287943.1_48624001_2 - 4.1 7.6 16.8 0.54 10.4 5.2 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Dev_Cell_Death PF10539.7 001288399.1_48623001_2 - 1.6e-40 137.8 0.0 2.6e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Development and cell death domain Phos_pyr_kin PF08543.10 001287944.1_48623001_2 - 2.5e-15 56.4 0.0 3.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.22 001287944.1_48623001_2 - 5e-09 35.7 0.0 7.2e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.15 001287944.1_48623001_2 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase TRAP_beta PF05753.12 001288185.1_48622001_2 - 8.1e-60 201.1 0.1 1.1e-59 200.7 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Ribosomal_L36e PF01158.16 001287945.1_48621001_1 - 2.5e-44 149.3 8.0 2.8e-44 149.2 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Ist1 PF03398.12 001288402.1_48624001_3 - 6e-58 195.2 4.3 8.5e-58 194.7 4.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway GTP_EFTU PF00009.25 001287946.1_48624001_3 - 6.8e-53 179.0 0.1 1.5e-52 177.8 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001287946.1_48624001_3 - 8.1e-39 132.3 0.0 1.8e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001287946.1_48624001_3 - 1e-12 48.1 0.3 2.6e-12 46.8 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001287946.1_48624001_3 - 0.002 18.0 0.2 0.0074 16.2 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.8 001287946.1_48624001_3 - 0.025 13.9 0.1 0.31 10.3 0.1 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.4 001287946.1_48624001_3 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FlpD PF02662.14 001287946.1_48624001_3 - 0.13 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit DOG1 PF14144.4 001288403.1_48623001_2 - 4.4e-31 106.8 0.2 2.6e-30 104.3 0.0 2.3 2 0 0 2 2 2 1 Seed dormancy control bZIP_1 PF00170.19 001288403.1_48623001_2 - 5e-08 32.8 9.2 1.4e-07 31.4 9.2 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001288403.1_48623001_2 - 0.0001 22.1 10.5 0.0001 22.1 10.5 2.3 2 0 0 2 2 2 1 Basic region leucine zipper RTTN_N PF14726.4 001288403.1_48623001_2 - 0.022 15.5 1.6 0.56 11.0 0.1 2.5 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Exonuc_VII_L PF02601.13 001288403.1_48623001_2 - 0.65 9.4 7.8 0.09 12.2 1.7 2.0 1 1 0 2 2 2 0 Exonuclease VII, large subunit Peptidase_C1 PF00112.21 001287948.1_48624001_1 - 1.4e-82 276.9 2.3 2.1e-82 276.3 2.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001287948.1_48624001_1 - 4.9e-18 65.2 0.7 1.1e-17 64.1 0.7 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Granulin PF00396.16 001287948.1_48624001_1 - 3.3e-11 43.2 25.3 3.3e-11 43.2 25.3 2.1 1 1 1 2 2 2 1 Granulin Peptidase_C1_2 PF03051.13 001287948.1_48624001_1 - 0.00039 19.2 1.2 0.022 13.4 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family NAM PF02365.13 001288405.1_48623001_1 - 1.2e-28 99.6 1.3 1.6e-28 99.3 0.4 1.7 2 0 0 2 2 2 1 No apical meristem (NAM) protein BAGE PF08180.9 001288188.1_48622001_1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 B melanoma antigen family RRM_1 PF00076.20 001288188.1_48622001_2 - 3e-13 49.2 0.0 4.8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alfin PF12165.6 001287949.1_48622001_1 - 1.5e-66 221.7 0.0 2e-66 221.3 0.0 1.2 1 0 0 1 1 1 1 Alfin PHD PF00628.27 001287949.1_48622001_1 - 6.6e-11 41.8 11.6 1.2e-10 40.9 11.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.14 001287949.1_48622001_1 - 0.027 14.7 2.4 0.027 14.7 2.4 2.2 2 0 0 2 2 2 0 C1 domain Ta0938 PF11494.6 001287949.1_48622001_1 - 0.035 14.3 2.6 0.074 13.2 2.6 1.5 1 0 0 1 1 1 0 Ta0938 Zf_RING PF16744.3 001287949.1_48622001_1 - 0.13 12.3 4.9 0.26 11.3 4.9 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.4 001287949.1_48622001_1 - 0.15 12.2 10.1 0.24 11.5 10.1 1.4 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.20 001287949.1_48622001_1 - 1.3 8.8 10.1 0.13 12.0 5.5 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DHquinase_I PF01487.13 001288406.1_48624001_1 - 5.7e-75 252.3 0.0 1.6e-74 250.9 0.0 1.8 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.9 001288406.1_48624001_1 - 1.2e-22 79.8 0.0 3e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.18 001288406.1_48624001_1 - 2.2e-10 40.6 0.0 5.7e-10 39.3 0.0 1.7 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.16 001288406.1_48624001_1 - 4.2e-05 23.7 0.1 0.025 14.7 0.0 2.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.15 001288406.1_48624001_1 - 0.00027 21.3 3.5 0.00061 20.2 1.0 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.17 001288406.1_48624001_1 - 0.00064 19.0 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.22 001288406.1_48624001_1 - 0.00065 18.8 0.3 0.001 18.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain IlvN PF07991.10 001288406.1_48624001_1 - 0.0023 17.4 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.19 001288406.1_48624001_1 - 0.0045 16.9 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peripla_BP_6 PF13458.4 001288406.1_48624001_1 - 0.0058 16.2 0.0 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 Periplasmic binding protein AlaDh_PNT_C PF01262.19 001288406.1_48624001_1 - 0.0073 15.5 0.3 0.015 14.4 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.23 001288406.1_48624001_1 - 0.033 13.5 2.4 0.039 13.3 0.8 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Pyr_redox_2 PF07992.12 001288406.1_48624001_1 - 0.044 12.9 0.2 0.065 12.3 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.13 001288406.1_48624001_1 - 0.091 12.8 0.3 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.20 001288406.1_48624001_1 - 0.14 11.0 0.9 0.26 10.2 0.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A IF3_N PF05198.14 001288406.1_48624001_1 - 0.15 12.2 0.0 1.5 9.0 0.0 2.5 3 0 0 3 3 2 0 Translation initiation factor IF-3, N-terminal domain NAD_Gly3P_dh_N PF01210.21 001288406.1_48624001_1 - 0.16 11.8 0.1 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.22 001288406.1_48624001_1 - 0.3 10.5 1.3 1.5 8.3 0.9 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.12 001288406.1_48624001_1 - 0.45 9.0 1.7 0.68 8.4 1.7 1.2 1 0 0 1 1 1 0 HI0933-like protein UQ_con PF00179.24 001288407.1_48622001_1 - 1.5e-46 157.4 0.1 2e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001288407.1_48622001_1 - 0.0034 17.5 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.4 001288407.1_48622001_1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.11 001288407.1_48622001_1 - 0.041 13.6 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 UEV domain Ribosomal_60s PF00428.17 001288190.1_48622001_1 - 4e-07 30.4 2.9 5.8e-07 29.9 2.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.17 001288190.1_48622001_2 - 1e-09 38.7 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein IF4E PF01652.16 001288408.1_48622001_1 - 2.5e-52 176.7 1.0 3e-52 176.5 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Glyco_hydro_16 PF00722.19 001287951.1_48622001_1 - 4.9e-61 205.1 0.4 4.9e-61 205.1 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 XET_C PF06955.10 001287951.1_48622001_1 - 2.7e-18 65.5 2.3 6e-18 64.4 2.3 1.6 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus Pyr_redox_2 PF07992.12 001288410.1_48624001_1 - 2e-70 237.2 4.7 3e-70 236.7 4.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.20 001288410.1_48624001_1 - 2.5e-40 137.0 1.1 3.9e-40 136.4 0.3 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.25 001288410.1_48624001_1 - 1.3e-25 89.6 4.9 6.7e-21 74.5 0.2 3.1 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.4 001288410.1_48624001_1 - 1.5e-12 47.3 4.9 6.9e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001288410.1_48624001_1 - 5.4e-12 45.4 3.0 4.4e-11 42.3 0.9 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.5 001288410.1_48624001_1 - 6.5e-12 45.4 1.0 8.3e-11 41.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.4 001288410.1_48624001_1 - 7.2e-08 32.4 1.6 9.2e-06 25.7 0.4 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.22 001288410.1_48624001_1 - 2.5e-07 30.0 10.7 4.1e-07 29.3 1.5 3.1 2 1 2 4 4 4 2 FAD binding domain AlaDh_PNT_C PF01262.19 001288410.1_48624001_1 - 1.2e-06 27.9 0.9 0.016 14.4 0.0 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.12 001288410.1_48624001_1 - 2.5e-05 23.0 10.8 9.2e-05 21.2 0.9 3.4 3 1 1 4 4 4 2 HI0933-like protein Thi4 PF01946.15 001288410.1_48624001_1 - 8.9e-05 21.7 3.6 0.00033 19.8 0.1 3.0 3 0 0 3 3 3 1 Thi4 family K_oxygenase PF13434.4 001288410.1_48624001_1 - 0.00011 21.3 0.8 0.11 11.5 0.0 2.8 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.22 001288410.1_48624001_1 - 0.00025 20.7 9.3 0.032 13.7 0.2 3.9 5 0 0 5 5 5 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.17 001288410.1_48624001_1 - 0.00025 20.3 8.3 0.0076 15.4 0.8 3.2 2 1 1 3 3 3 1 FAD binding domain UDPG_MGDP_dh_N PF03721.12 001288410.1_48624001_1 - 0.00046 19.7 2.2 0.0012 18.3 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.16 001288410.1_48624001_1 - 0.00092 19.0 4.2 0.0014 18.4 0.1 3.0 4 0 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.10 001288410.1_48624001_1 - 0.0047 15.9 0.6 0.17 10.7 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein SE PF08491.8 001288410.1_48624001_1 - 0.031 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase XdhC_C PF13478.4 001288410.1_48624001_1 - 0.07 13.5 0.1 14 6.1 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain PsbT PF01405.15 001288411.1_48623001_1 - 0.12 12.1 4.6 0.24 11.1 4.6 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein DUF1313 PF07011.9 001288411.1_48623001_3 - 1.1e-40 137.3 4.3 1.6e-40 136.8 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1313) DUF3474 PF11960.6 001287954.1_48624001_1 - 1.1e-52 177.4 0.2 2e-52 176.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.22 001287954.1_48624001_1 - 1.5e-31 110.1 24.9 2.3e-31 109.5 24.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase NUDIX PF00293.26 001287955.1_48622001_1 - 9.5e-16 57.9 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Fer4 PF00037.25 001288413.1_48623001_1 - 8.5e-14 50.6 16.9 3e-08 33.0 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.5 001288413.1_48623001_1 - 5.8e-13 49.1 10.5 9.8e-13 48.4 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.4 001288413.1_48623001_1 - 3.2e-10 40.7 6.3 8.3e-05 23.3 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.4 001288413.1_48623001_1 - 2.6e-08 33.7 10.5 4.6e-08 33.0 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.4 001288413.1_48623001_1 - 3.2e-08 33.4 31.7 1.1e-05 25.4 12.3 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.4 001288413.1_48623001_1 - 7e-08 32.3 21.4 2.8e-06 27.2 12.3 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.5 001288413.1_48623001_1 - 9.8e-07 28.5 17.8 0.00067 19.5 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.5 001288413.1_48623001_1 - 1.4e-06 27.9 12.1 0.0048 16.8 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.4 001288413.1_48623001_1 - 1.8e-06 28.2 8.2 0.00051 20.3 11.4 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.5 001288413.1_48623001_1 - 3.8e-05 23.7 12.3 0.00083 19.5 2.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.4 001288413.1_48623001_1 - 0.0011 19.4 12.4 0.07 13.5 13.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.4 001288413.1_48623001_1 - 0.037 14.4 14.7 0.97 9.9 2.6 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.4 001288413.1_48623001_1 - 0.074 13.1 8.7 2.8 8.0 1.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.8 001288413.1_48623001_1 - 0.15 12.2 8.9 0.43 10.7 0.3 2.9 2 1 1 3 3 3 0 c-SKI Smad4 binding domain ETF_QO PF05187.11 001288413.1_48623001_1 - 0.16 12.0 5.1 0.45 10.5 0.4 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.5 001288413.1_48623001_1 - 0.54 11.2 16.4 0.57 11.1 4.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.2 001288413.1_48623001_1 - 6.8 7.5 14.5 4.3 8.1 1.8 2.7 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.4 001288413.1_48623001_1 - 9.7 6.9 11.6 10 6.8 3.6 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Cytokin-bind PF09265.8 001288192.1_48624001_1 - 3.1e-106 354.8 1.1 3.8e-106 354.5 1.1 1.1 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 001288192.1_48624001_1 - 3.2e-23 81.9 1.9 5.9e-23 81.0 1.9 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S3Ae PF01015.16 001288194.1_48623001_3 - 3.1e-99 330.6 4.8 3.8e-99 330.3 4.8 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family CBFD_NFYB_HMF PF00808.21 001288414.1_48623001_3 - 3.2e-22 78.4 1.1 5.3e-22 77.8 1.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001288414.1_48623001_3 - 1.8e-17 63.9 3.3 2.8e-17 63.2 3.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 BAF1_ABF1 PF04684.11 001288414.1_48623001_3 - 0.063 12.1 5.2 0.086 11.7 5.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.23 001287962.1_48623001_1 - 5.9e-71 238.8 0.0 7.6e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001287962.1_48623001_1 - 5.9e-34 117.4 0.0 8.3e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.18 001287962.1_48623001_1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.21 001287962.1_48623001_1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNA_pol_3_Rpc31 PF11705.6 001287962.1_48623001_1 - 1.1 9.3 12.7 2.3 8.2 12.7 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_S13 PF00416.20 001288197.1_48622001_3 - 1e-53 181.0 1.3 1.3e-53 180.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pkinase PF00069.23 001287963.1_48623001_1 - 1.9e-72 243.6 0.0 2.8e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001287963.1_48623001_1 - 4e-34 118.0 0.0 6e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_3_Rpc31 PF11705.6 001287963.1_48623001_1 - 0.00014 22.0 6.5 0.00025 21.2 6.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 HTH_WhiA PF02650.12 001287963.1_48623001_1 - 0.0023 18.1 0.4 0.0076 16.4 0.0 2.0 2 0 0 2 2 2 1 WhiA C-terminal HTH domain Choline_kinase PF01633.18 001287963.1_48623001_1 - 0.022 14.2 0.0 0.065 12.7 0.0 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.21 001287963.1_48623001_1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.12 001287963.1_48623001_1 - 0.04 13.1 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_phi PF04931.11 001287963.1_48623001_1 - 1.2 7.0 6.5 1.6 6.6 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi eIF3_subunit PF08597.8 001287963.1_48623001_1 - 7.2 6.3 12.3 4.4 7.0 9.9 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit UQ_con PF00179.24 001288198.1_48622001_2 - 2.6e-53 179.3 0.0 3.4e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001288198.1_48622001_2 - 0.005 17.0 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.4 001288198.1_48622001_2 - 0.02 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.11 001288198.1_48622001_2 - 0.053 13.3 0.4 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 UEV domain Ion_trans PF00520.29 001288418.1_48626001_2 - 1.9e-38 132.0 9.9 3e-38 131.3 9.9 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.5 001288418.1_48626001_2 - 1.6e-25 89.4 0.1 2.3e-11 44.0 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) KHA PF11834.6 001288418.1_48626001_2 - 1.5e-21 76.1 0.0 2.7e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Ank PF00023.28 001288418.1_48626001_2 - 1.6e-19 69.2 0.1 1.7e-05 25.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.4 001288418.1_48626001_2 - 1.3e-17 63.8 0.2 5.4e-05 23.5 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.4 001288418.1_48626001_2 - 1.7e-17 63.1 0.6 3.5e-07 30.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) cNMP_binding PF00027.27 001288418.1_48626001_2 - 2e-15 56.5 0.0 4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ank_3 PF13606.4 001288418.1_48626001_2 - 6.9e-15 53.5 1.0 0.00021 21.3 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ion_trans_2 PF07885.14 001288418.1_48626001_2 - 2e-13 50.0 3.3 2e-13 50.0 3.3 2.0 2 0 0 2 2 2 1 Ion channel CRAL_TRIO PF00650.18 001287964.1_48623001_1 - 1.3e-36 125.6 0.0 1.7e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.13 001287964.1_48623001_1 - 6.7e-08 32.5 0.1 1.4e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.4 001287964.1_48623001_1 - 8.5e-07 29.0 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain ArfGap PF01412.16 001288200.1_48624001_3 - 4.1e-33 113.7 0.4 2.3e-32 111.3 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.15 001288200.1_48624001_3 - 0.16 11.8 0.3 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Ribosomal_S11 PF00411.17 001287966.1_48622001_1 - 2.9e-47 159.5 0.6 3.9e-47 159.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.11 001287966.1_48622001_1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Pollen_allerg_1 PF01357.19 001288420.1_48622001_3 - 2.7e-20 72.1 0.4 5e-20 71.2 0.4 1.5 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001288420.1_48622001_3 - 1.5e-12 47.5 0.2 3.4e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 Lytic transglycolase UQ_con PF00179.24 001287967.1_48622001_1 - 6.7e-43 145.6 0.0 8.2e-43 145.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001287967.1_48622001_1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Proteasome PF00227.24 001288421.1_48623001_1 - 2.5e-59 199.8 0.0 3.3e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001288421.1_48623001_1 - 7.2e-15 54.2 0.1 1.5e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Amidohydro_1 PF01979.18 001288202.1_48626001_1 - 3.6e-76 256.6 2.4 5.2e-76 256.0 2.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.18 001288202.1_48626001_1 - 4.8e-51 172.0 0.5 1.1e-50 170.9 0.5 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.16 001288202.1_48626001_1 - 1.8e-40 137.1 0.2 6.8e-40 135.2 0.0 2.1 3 0 0 3 3 3 1 Urease, gamma subunit Urease_beta PF00699.18 001288202.1_48626001_1 - 2.4e-37 126.8 0.0 4.7e-37 125.8 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.9 001288202.1_48626001_1 - 5.3e-08 32.6 0.4 7.4e-05 22.3 0.0 2.5 1 1 1 2 2 2 2 Amidohydrolase family Lipoxygenase PF00305.17 001288422.1_48626001_3 - 0 1062.8 0.0 0 1062.5 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001288422.1_48626001_3 - 1.9e-19 70.2 0.1 3.8e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Pkinase PF00069.23 001287969.1_48624001_3 - 2e-70 237.1 0.0 2.6e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001287969.1_48624001_3 - 1.4e-33 116.2 0.0 1.9e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001287969.1_48624001_3 - 0.00052 19.3 0.1 0.00078 18.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001287969.1_48624001_3 - 0.0013 17.9 0.0 0.0032 16.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like bHLH-MYC_N PF14215.4 001288203.1_48624001_1 - 1.8e-52 178.0 0.0 4.2e-52 176.7 0.0 1.7 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 001288203.1_48624001_1 - 4.4e-11 42.4 1.4 1.3e-10 41.0 1.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IF4E PF01652.16 001288204.1_48622001_1 - 1.3e-51 174.4 3.9 1.5e-51 174.2 3.9 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Glyco_hydro_19 PF00182.17 001318619.1_48623001_3 - 4.7e-130 432.3 2.6 4.7e-130 432.3 2.6 1.9 2 0 0 2 2 2 1 Chitinase class I Chitin_bind_1 PF00187.17 001318619.1_48623001_3 - 6.5e-13 48.8 21.1 6.5e-13 48.8 21.1 3.1 3 0 0 3 3 3 1 Chitin recognition protein LYTB PF02401.16 001287970.1_48624001_1 - 4.3e-79 265.4 0.1 5.4e-79 265.1 0.1 1.1 1 0 0 1 1 1 1 LytB protein Cna_B PF05738.11 001287970.1_48624001_1 - 0.51 10.8 5.0 0.33 11.4 0.2 2.9 3 0 0 3 3 3 0 Cna protein B-type domain PfkB PF00294.22 001287971.1_48623001_1 - 8.7e-80 268.1 0.0 1e-79 267.9 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_L23eN PF03939.11 001288424.1_48622001_1 - 1.6e-17 63.3 12.0 1.6e-17 63.3 12.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.18 001288424.1_48622001_1 - 7.3e-13 48.6 4.2 7.3e-13 48.6 4.2 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 Epimerase PF01370.19 001287972.1_48623001_1 - 9.4e-28 97.1 0.0 1.2e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001287972.1_48623001_1 - 1.3e-19 70.2 0.0 1.7e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001287972.1_48623001_1 - 4.8e-19 68.9 0.0 6.6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.3 001287972.1_48623001_1 - 2.2e-14 53.4 0.0 2.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.11 001287972.1_48623001_1 - 5.7e-12 45.6 0.0 8.6e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.10 001287972.1_48623001_1 - 7.9e-11 41.5 0.1 9.8e-10 37.9 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.13 001287972.1_48623001_1 - 5.6e-07 28.9 0.0 8.8e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.23 001287972.1_48623001_1 - 8.8e-07 28.4 0.0 0.00039 19.8 0.0 2.6 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.8 001287972.1_48623001_1 - 0.00012 21.9 0.0 0.00049 19.9 0.0 1.8 1 1 0 1 1 1 1 KR domain S1-P1_nuclease PF02265.14 001287973.1_48622001_1 - 1.7e-80 270.3 0.1 1.9e-80 270.1 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease LSM PF01423.20 001287974.1_48623001_1 - 2.4e-16 59.0 0.0 3.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.4 001287974.1_48623001_1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain ABC2_membrane PF01061.22 001288427.1_48629001_1 - 8.3e-71 237.6 56.4 5.9e-38 130.3 20.6 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.25 001288427.1_48629001_1 - 8.8e-36 123.3 0.0 7.2e-19 68.5 0.0 3.3 2 1 1 3 3 3 3 ABC transporter PDR_assoc PF08370.9 001288427.1_48629001_1 - 9.6e-30 102.0 0.6 9.6e-30 102.0 0.6 2.9 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_21 PF13304.4 001288427.1_48629001_1 - 6.9e-10 39.1 0.2 0.016 14.9 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_trans_N PF14510.4 001288427.1_48629001_1 - 7.4e-10 39.1 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.4 001288427.1_48629001_1 - 2.7e-06 27.0 0.6 0.0092 15.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.4 001288427.1_48629001_1 - 1.7e-05 25.1 0.1 0.18 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.4 001288427.1_48629001_1 - 2.1e-05 24.0 3.9 0.061 12.9 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.14 001288427.1_48629001_1 - 0.00012 21.9 1.6 0.075 12.8 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA PF00004.27 001288427.1_48629001_1 - 0.0002 21.6 0.3 0.38 11.1 0.0 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.4 001288427.1_48629001_1 - 0.00034 21.0 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.4 001288427.1_48629001_1 - 0.00087 19.4 1.4 0.28 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.4 001288427.1_48629001_1 - 0.001 19.2 0.2 1.5 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.17 001288427.1_48629001_1 - 0.0012 18.2 0.0 7.2 5.8 0.0 3.5 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.4 001288427.1_48629001_1 - 0.0024 17.9 1.2 2.2 8.3 0.4 2.7 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.13 001288427.1_48629001_1 - 0.01 15.6 2.1 0.56 10.0 0.0 3.2 3 0 0 3 3 3 0 NTPase RecA PF00154.19 001288427.1_48629001_1 - 0.011 15.1 0.1 0.047 13.0 0.0 2.0 2 0 0 2 2 2 0 recA bacterial DNA recombination protein MMR_HSR1 PF01926.21 001288427.1_48629001_1 - 0.012 15.5 0.2 6.3 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.10 001288427.1_48629001_1 - 0.044 13.6 0.2 8.9 6.1 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.4 001288427.1_48629001_1 - 0.073 13.4 3.9 3.2 8.1 0.2 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.17 001288427.1_48629001_1 - 0.074 12.5 3.0 5.7 6.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.4 001288427.1_48629001_1 - 0.082 12.5 0.4 15 5.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.11 001288427.1_48629001_1 - 0.09 12.9 0.4 8.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.7 001288427.1_48629001_1 - 0.16 11.6 1.2 7.7 6.1 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.4 001288427.1_48629001_1 - 0.19 11.3 3.9 4 7.0 1.0 2.5 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.20 001287975.1_48624001_1 - 3.8e-16 58.5 0.0 5.3e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001287975.1_48624001_1 - 3e-05 23.6 0.1 4.7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.4 001287975.1_48624001_1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001287975.1_48624001_1 - 0.049 13.5 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Macoilin PF09726.7 001287975.1_48624001_1 - 0.41 9.0 3.1 0.46 8.9 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L28e PF01778.15 001287976.1_48622001_1 - 3.3e-35 121.1 2.9 4.1e-35 120.8 2.9 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family V-ATPase_G PF03179.13 001288208.1_48622001_2 - 4.7e-33 113.7 10.6 6.2e-33 113.3 10.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Aminotran_1_2 PF00155.19 001287977.1_48624001_3 - 6.3e-96 321.6 0.0 7.8e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_6 PF12697.5 001287978.1_48623001_1 - 1.3e-18 68.3 0.4 1.8e-18 67.8 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001287978.1_48623001_1 - 5.9e-17 62.0 0.0 3.9e-16 59.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001287978.1_48623001_1 - 1.9e-11 43.6 0.0 4.1e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.9 001287978.1_48623001_1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.5 001287978.1_48623001_1 - 0.038 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Voltage_CLC PF00654.18 001288211.1_48626001_2 - 4.1e-90 302.4 21.9 4.1e-90 302.4 21.9 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.26 001288211.1_48626001_2 - 7.8e-09 35.7 0.0 9.6e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain TAXi_C PF14541.4 001287979.1_48623001_1 - 1.8e-51 174.0 0.0 2.8e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.4 001287979.1_48623001_1 - 5.6e-36 124.3 0.2 5.6e-36 124.3 0.2 1.5 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal ATP-synt_G PF04718.13 001287980.1_48622001_2 - 3e-24 85.6 0.1 4.6e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit EBP PF05241.10 001288433.1_48622001_3 - 1.2e-57 194.2 12.4 1.4e-57 193.8 12.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein Sucrose_synth PF00862.17 001287982.1_48626001_2 - 2.9e-278 923.5 0.0 4.4e-278 923.0 0.0 1.3 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001287982.1_48626001_2 - 1.3e-33 115.9 0.0 3.5e-33 114.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001287982.1_48626001_2 - 2.2e-12 47.4 0.0 6e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001287982.1_48626001_2 - 1e-05 25.7 0.0 2.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_CodY PF08222.9 001287982.1_48626001_2 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain NAM PF02365.13 001288214.1_48623001_1 - 2.4e-26 92.3 0.2 3.9e-26 91.6 0.2 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein Pkinase PF00069.23 001287983.1_48623001_1 - 8.8e-75 251.3 0.0 1.1e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001287983.1_48623001_1 - 2.1e-33 115.6 0.0 2.7e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.18 001287983.1_48623001_1 - 0.0097 15.4 0.5 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.21 001287983.1_48623001_1 - 0.029 14.1 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family GAGA_bind PF06217.10 001288435.1_48623001_1 - 5.7e-105 351.7 6.5 7.1e-105 351.4 6.5 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family DUF390 PF04094.12 001288435.1_48623001_1 - 0.0031 15.8 2.8 0.0047 15.2 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF390) Cys_Met_Meta_PP PF01053.18 001288215.1_48624001_3 - 1.2e-139 465.0 0.0 1.4e-139 464.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.17 001288215.1_48624001_3 - 5.6e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.19 001288215.1_48624001_3 - 0.00033 19.9 0.0 0.00079 18.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Ribosomal_S3Ae PF01015.16 001287984.1_48623001_2 - 2.3e-99 331.0 4.8 2.8e-99 330.7 4.8 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family p450 PF00067.20 001288216.1_48625001_3 - 3.2e-77 260.1 0.0 4.6e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 EF1_GNE PF00736.17 001287985.1_48622001_1 - 5e-33 113.0 0.9 8.1e-33 112.3 0.9 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_3 PF14497.4 001287985.1_48622001_1 - 0.0018 18.3 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001287985.1_48622001_1 - 0.14 12.0 0.0 1.1 9.1 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MMgT PF10270.7 001288436.1_48621001_1 - 2.2e-10 40.6 0.0 2.5e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter FtsX PF02687.19 001288436.1_48621001_1 - 0.11 12.3 0.9 0.14 12.0 0.9 1.1 1 0 0 1 1 1 0 FtsX-like permease family DSPc PF00782.18 001288437.1_48626001_1 - 7.3e-30 103.4 0.0 1.2e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.20 001288437.1_48626001_1 - 9.5e-07 28.5 1.6 4.2e-05 23.2 0.0 3.4 4 0 0 4 4 4 1 Gelsolin repeat Y_phosphatase PF00102.25 001288437.1_48626001_1 - 0.0022 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase V-SNARE PF05008.13 001287988.1_48623001_1 - 7.5e-27 93.4 2.1 7.5e-27 93.4 2.1 1.7 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.6 001287988.1_48623001_1 - 2.3e-21 75.7 8.7 4.5e-21 74.8 6.9 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.11 001287988.1_48623001_1 - 4.3e-07 29.6 1.3 9.5e-07 28.5 0.8 1.9 1 1 0 1 1 1 1 Sec20 Pox_EPC_I2-L1 PF12575.6 001287988.1_48623001_1 - 0.025 14.6 0.6 0.058 13.5 0.6 1.6 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Fusion_gly PF00523.16 001287988.1_48623001_1 - 0.031 12.4 2.8 0.034 12.3 0.7 2.0 1 1 1 2 2 2 0 Fusion glycoprotein F0 Spectrin PF00435.19 001287988.1_48623001_1 - 0.085 13.2 2.8 0.081 13.3 0.6 1.9 1 1 1 2 2 2 0 Spectrin repeat Prominin PF05478.9 001287988.1_48623001_1 - 0.49 8.1 7.3 2.9 5.6 7.3 2.0 1 1 0 1 1 1 0 Prominin DUF883 PF05957.11 001287988.1_48623001_1 - 0.69 10.4 5.2 0.47 10.9 0.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.13 001287988.1_48623001_1 - 0.77 9.1 11.2 0.55 9.6 7.0 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit Aminotran_1_2 PF00155.19 001288438.1_48624001_1 - 1.4e-103 346.7 0.0 1.7e-103 346.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.18 001288438.1_48624001_1 - 0.028 12.8 0.0 0.047 12.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.19 001288438.1_48624001_1 - 0.093 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase POX PF07526.9 001288439.1_48625001_3 - 1e-50 171.8 1.2 1e-50 171.8 1.2 2.4 2 0 0 2 2 2 1 Associated with HOX Homeobox_KN PF05920.9 001288439.1_48625001_3 - 2.2e-18 65.7 0.1 4.7e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.27 001288439.1_48625001_3 - 2.8e-07 30.1 0.1 9.1e-07 28.5 0.1 1.9 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.6 001288439.1_48625001_3 - 0.018 14.3 0.3 0.37 10.2 0.0 2.7 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez UTP25 PF06862.10 001288439.1_48625001_3 - 0.025 13.2 0.4 0.041 12.5 0.0 1.5 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF1043 PF06295.10 001288439.1_48625001_3 - 0.028 14.3 0.5 0.54 10.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF913 PF06025.10 001288439.1_48625001_3 - 0.26 10.1 7.1 0.075 11.8 0.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Cupin_1 PF00190.20 001288440.1_48622001_1 - 1.2e-43 148.2 1.9 1.5e-43 147.8 1.9 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.9 001288440.1_48622001_1 - 9.2e-12 44.4 0.1 1.5e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.5 001288440.1_48622001_1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain Myb_CC_LHEQLE PF14379.4 001288222.1_48623001_3 - 2.9e-23 81.2 18.2 4.5e-23 80.6 18.2 1.3 1 0 0 1 1 1 1 MYB-CC type transfactor, LHEQLE motif Myb_DNA-binding PF00249.29 001288222.1_48623001_3 - 1.1e-09 38.1 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Curto_V2 PF07325.9 001288222.1_48623001_3 - 0.11 12.3 0.2 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Curtovirus V2 protein Metallophos PF00149.26 001318640.1_48626001_1 - 3.7e-33 115.6 0.0 7.2e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_4 PF13418.4 001318640.1_48626001_1 - 3.9e-21 74.6 11.7 3.1e-05 23.7 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.4 001318640.1_48626001_1 - 4e-20 71.4 13.2 0.00033 20.7 0.1 6.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.4 001318640.1_48626001_1 - 1.9e-16 59.5 3.2 1.2e-05 25.1 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.23 001318640.1_48626001_1 - 5e-10 38.7 0.4 0.018 14.5 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.4 001318640.1_48626001_1 - 2.3e-09 37.1 0.5 0.027 14.6 0.0 6.0 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.13 001318640.1_48626001_1 - 8e-07 28.7 3.8 0.14 12.1 0.0 5.7 6 1 0 6 6 6 2 Kelch motif STPPase_N PF16891.3 001318640.1_48626001_1 - 3e-06 27.4 0.0 5.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain RAG2 PF03089.12 001318640.1_48626001_1 - 0.031 13.1 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Recombination activating protein 2 Tubulin PF00091.23 001288224.1_48623001_1 - 7.6e-42 143.6 0.5 1.2e-41 142.9 0.5 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.6 001288224.1_48623001_1 - 5.1e-30 103.5 2.4 8.9e-30 102.7 1.3 2.0 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.4 001288224.1_48623001_1 - 0.014 14.5 0.4 0.065 12.3 0.0 2.0 2 0 0 2 2 2 0 Tubulin like dUTPase PF00692.17 001288224.1_48623001_1 - 0.058 12.9 0.6 3.4 7.2 0.1 2.5 1 1 1 2 2 2 0 dUTPase Profilin PF00235.17 001288441.1_48622001_3 - 2e-43 147.5 0.0 2.4e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Profilin Peptidase_M16 PF00675.18 001287995.1_48624001_2 - 8.6e-40 136.0 0.0 1.5e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001287995.1_48624001_2 - 6.4e-30 104.4 0.0 1.1e-29 103.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain bZIP_1 PF00170.19 001287996.1_48624001_3 - 4e-13 49.1 14.4 7.1e-13 48.3 14.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001287996.1_48624001_3 - 8.3e-11 41.7 15.9 1.6e-10 40.8 15.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001287996.1_48624001_3 - 0.00013 22.3 7.5 0.00013 22.3 7.5 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF3664 PF12406.6 001287996.1_48624001_3 - 0.81 10.2 7.8 1.9 9.0 7.8 1.5 1 0 0 1 1 1 0 Surface protein V_ATPase_I PF01496.17 001287996.1_48624001_3 - 1.3 6.7 7.6 1.9 6.2 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS6_N PF14661.4 001287996.1_48624001_3 - 1.8 8.0 7.4 3 7.3 7.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Pkinase PF00069.23 001288442.1_48624001_1 - 2.7e-75 253.0 0.0 4.4e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.30 001288442.1_48624001_1 - 3.1e-34 113.8 5.1 5e-09 34.9 0.1 4.8 5 0 0 5 5 5 4 EF hand Pkinase_Tyr PF07714.15 001288442.1_48624001_1 - 9.5e-32 110.2 0.0 1.4e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.4 001288442.1_48624001_1 - 1.2e-30 105.7 0.8 1e-14 54.6 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001288442.1_48624001_1 - 4e-25 85.5 3.5 2.4e-07 30.0 0.1 5.1 3 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001288442.1_48624001_1 - 1.1e-24 84.6 0.7 8.2e-06 25.0 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001288442.1_48624001_1 - 3.2e-23 81.1 4.6 9.9e-11 41.1 0.2 4.4 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001288442.1_48624001_1 - 2.6e-09 37.2 0.0 0.00097 19.3 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001288442.1_48624001_1 - 2.7e-08 33.5 0.1 0.0056 16.5 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001288442.1_48624001_1 - 2.5e-05 24.4 0.1 0.018 15.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.9 001288442.1_48624001_1 - 0.00027 21.6 0.0 0.05 14.3 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain Kinase-like PF14531.4 001288442.1_48624001_1 - 0.00076 18.7 0.0 0.0064 15.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.12 001288442.1_48624001_1 - 0.002 17.4 0.1 0.0052 16.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EFhand_Ca_insen PF08726.8 001288442.1_48624001_1 - 0.0075 16.2 0.1 3.3 7.7 0.0 2.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand APH PF01636.21 001288442.1_48624001_1 - 0.01 15.7 0.0 4.2 7.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.24 001288227.1_48622001_2 - 3.3e-52 175.7 0.0 4.2e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001288227.1_48622001_2 - 0.00012 21.6 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001288227.1_48622001_2 - 0.026 14.7 0.0 0.093 12.9 0.0 1.9 2 0 0 2 2 2 0 RWD domain GST_N_3 PF13417.4 001288443.1_48622001_1 - 4.1e-17 62.2 0.0 7.1e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001288443.1_48622001_1 - 2.2e-12 47.0 0.0 4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001288443.1_48622001_1 - 1.6e-06 28.3 0.0 3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001288443.1_48622001_1 - 3.6e-06 26.7 0.0 6.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 001288443.1_48622001_1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin GST_N_4 PF17172.2 001288443.1_48622001_1 - 0.14 12.8 0.1 0.35 11.5 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Tocopherol_cycl PF14249.4 001287998.1_48624001_2 - 1.5e-146 487.8 7.9 1.8e-146 487.4 7.9 1.1 1 0 0 1 1 1 1 Tocopherol cyclase UQ_con PF00179.24 001288228.1_48622001_1 - 1.7e-52 176.6 0.0 2.1e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001288228.1_48622001_1 - 0.0028 17.8 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.4 001288228.1_48622001_1 - 0.0095 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.11 001288228.1_48622001_1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 UEV domain Ribosomal_L4 PF00573.20 001287999.1_48623001_1 - 5.7e-37 127.1 0.0 8.9e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.4 001287999.1_48623001_1 - 1.8e-30 104.6 5.0 1.8e-30 104.6 5.0 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Tim17 PF02466.17 001288447.1_48622001_3 - 1.6e-12 47.6 2.6 2.2e-12 47.1 2.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.4 001288447.1_48622001_3 - 0.011 15.3 5.8 0.41 10.3 1.8 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.4 001288447.1_48622001_3 - 0.12 12.3 5.9 0.31 11.0 3.3 2.3 2 0 0 2 2 2 0 Glycine zipper TraT PF05818.10 001288447.1_48622001_3 - 0.22 11.1 3.0 0.17 11.4 0.9 1.6 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Rick_17kDa_Anti PF05433.13 001288447.1_48622001_3 - 0.48 10.2 9.6 0.046 13.5 3.5 2.4 2 1 0 2 2 2 0 Glycine zipper 2TM domain WRKY PF03106.13 001288229.1_48623001_3 - 1.6e-25 89.1 3.0 1.6e-25 89.1 3.0 2.4 2 0 0 2 2 2 1 WRKY DNA -binding domain Ribosomal_L36e PF01158.16 001288230.1_48622001_3 - 2.5e-43 146.1 7.3 3.3e-43 145.7 7.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L36e 2OG-FeII_Oxy PF03171.18 001288001.1_48623001_1 - 1.2e-23 83.4 0.0 1.9e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001288001.1_48623001_1 - 9.4e-21 74.6 0.0 1.8e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Herpes_TK_C PF08465.8 001288231.1_48623001_2 - 0.13 11.8 0.4 0.3 10.7 0.4 1.6 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal Brix PF04427.16 001288231.1_48623001_3 - 3.8e-33 115.1 0.8 6.3e-33 114.4 0.8 1.4 1 0 0 1 1 1 1 Brix domain Suf PF05843.12 001288231.1_48623001_3 - 0.012 15.4 1.2 0.012 15.4 1.2 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AIRS_C PF02769.20 001288002.1_48624001_3 - 1.9e-37 128.6 0.0 2.8e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.22 001288002.1_48624001_3 - 2.1e-15 57.0 0.3 6e-15 55.5 0.3 1.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain S10_plectin PF03501.13 001288232.1_48622001_1 - 3e-42 142.5 0.4 3.9e-42 142.1 0.4 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Kinesin PF00225.21 001288451.1_48629001_3 - 7.5e-105 350.4 3.9 7.5e-105 350.4 3.9 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.3 001288451.1_48629001_3 - 4.1e-48 163.0 0.2 1.3e-47 161.4 0.2 1.9 1 0 0 1 1 1 1 Microtubule binding MyTH4 PF00784.15 001288451.1_48629001_3 - 2.2e-27 95.6 0.0 5.3e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.16 001288451.1_48629001_3 - 6.9e-18 65.0 0.0 6.9e-18 65.0 0.0 2.7 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.8 001288451.1_48629001_3 - 5.7e-13 48.5 0.0 1.5e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain Syntaxin-18_N PF10496.7 001288451.1_48629001_3 - 1.5 9.0 6.5 5.3 7.2 1.2 3.4 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4665 PF15679.3 001288451.1_48629001_3 - 3 8.4 18.7 0.5 10.9 2.0 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) ERM PF00769.17 001288451.1_48629001_3 - 8.1 6.0 48.1 1.4 8.6 28.9 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Leu_zip PF15294.4 001288451.1_48629001_3 - 8.6 5.7 43.5 1.6 8.0 29.3 2.8 1 1 2 3 3 3 0 Leucine zipper zf-C2H2_jaz PF12171.6 001288003.1_48624001_1 - 2.6e-05 24.2 0.4 2.6e-05 24.2 0.4 3.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.24 001288003.1_48624001_1 - 0.00015 21.9 14.3 0.025 14.9 0.7 4.4 2 1 1 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.5 001288003.1_48624001_1 - 0.00093 19.4 0.4 0.00093 19.4 0.4 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.13 001288003.1_48624001_1 - 0.062 13.2 1.1 4.9 7.1 0.1 2.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.4 001288003.1_48624001_1 - 2.2 8.8 17.1 0.039 14.3 3.5 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Pkinase PF00069.23 001288233.1_48622001_1 - 3.9e-72 242.7 0.0 4.4e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288233.1_48622001_1 - 9.9e-32 110.1 0.0 1.2e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001288233.1_48622001_1 - 1.3e-08 34.4 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001288233.1_48622001_1 - 0.0018 17.6 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001288233.1_48622001_1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_1 PF00561.18 001288452.1_48623001_3 - 1.9e-19 70.2 0.0 5.1e-19 68.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001288452.1_48623001_3 - 2.5e-19 70.6 0.2 3.4e-19 70.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001288452.1_48623001_3 - 5.9e-13 48.5 0.0 5.5e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.5 001288452.1_48623001_3 - 0.0042 15.9 0.0 0.006 15.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.9 001288452.1_48623001_3 - 0.0051 15.7 0.0 0.0074 15.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Ras PF00071.20 001288004.1_48622001_1 - 1.1e-49 168.0 0.0 1.4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001288004.1_48622001_1 - 2.8e-29 101.7 0.0 4.5e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001288004.1_48622001_1 - 4.8e-11 42.3 0.0 7.8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.20 001288004.1_48622001_1 - 1.7e-05 25.0 0.1 9.2e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.21 001288004.1_48622001_1 - 0.0014 18.5 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pox_A32 PF04665.10 001288004.1_48622001_1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.4 001288004.1_48622001_1 - 0.06 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.11 001288004.1_48622001_1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 KaiC DUF258 PF03193.14 001288004.1_48622001_1 - 0.074 12.8 0.0 9.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Peptidase_M16 PF00675.18 001288234.1_48624001_1 - 3.1e-53 179.6 0.0 4.7e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001288234.1_48624001_1 - 4.6e-38 130.9 0.0 1.3e-37 129.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain CGI-121 PF08617.8 001288005.1_48622001_2 - 1.6e-35 122.5 1.0 1.9e-35 122.2 1.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Ribosomal_S3Ae PF01015.16 001288235.1_48623001_2 - 6.5e-99 329.5 2.6 8.8e-99 329.1 2.6 1.2 1 0 0 1 1 1 1 Ribosomal S3Ae family Ras PF00071.20 001288454.1_48622001_3 - 1e-65 220.1 0.4 1.2e-65 219.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001288454.1_48622001_3 - 5.9e-36 123.2 0.1 9.3e-36 122.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001288454.1_48622001_3 - 7.2e-16 58.0 0.1 8.9e-16 57.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001288454.1_48622001_3 - 4.2e-06 26.6 0.3 0.044 13.5 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF258 SRPRB PF09439.8 001288454.1_48622001_3 - 2.2e-05 23.9 0.0 3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001288454.1_48622001_3 - 7e-05 22.1 0.0 8.9e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001288454.1_48622001_3 - 9e-05 22.0 0.3 0.00025 20.5 0.2 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001288454.1_48622001_3 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.27 001288454.1_48622001_3 - 0.003 17.9 0.0 1 9.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.4 001288454.1_48622001_3 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.4 001288454.1_48622001_3 - 0.075 13.3 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.7 001288454.1_48622001_3 - 0.075 12.6 0.0 1.8 8.2 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Adeno_terminal PF02459.13 001288454.1_48622001_3 - 0.098 10.9 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein AAA_22 PF13401.4 001288454.1_48622001_3 - 0.1 12.7 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain FKBP_C PF00254.26 001288006.1_48621001_1 - 1.1e-35 121.7 0.0 1.6e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Aminotran_4 PF01063.17 001288456.1_48624001_2 - 1e-39 136.5 0.0 1.3e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV PHO4 PF01384.18 001288238.1_48625001_1 - 2.4e-104 348.9 28.5 3.9e-104 348.2 28.5 1.3 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.8 001288238.1_48625001_1 - 0.042 13.5 0.2 0.92 9.2 0.0 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain LRR_9 PF14580.4 001288010.1_48623001_2 - 6.8e-81 269.8 4.1 1e-80 269.2 4.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.5 001288010.1_48623001_2 - 9e-07 29.0 18.1 0.0063 16.8 3.6 4.2 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001288010.1_48623001_2 - 1.8e-05 24.2 14.4 0.00062 19.4 4.1 3.3 1 1 2 3 3 3 3 Leucine rich repeat zf-A20 PF01754.14 001288458.1_48622001_3 - 2.7e-12 46.3 6.7 6.6e-12 45.0 6.7 1.7 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.14 001288458.1_48622001_3 - 3.2e-09 36.7 8.1 3.2e-09 36.7 8.1 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger MIP PF00230.18 001288459.1_48622001_1 - 2.3e-85 285.8 9.2 2.7e-85 285.6 9.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_U4 PF03419.11 001288459.1_48622001_1 - 2.3 7.3 8.1 0.97 8.5 4.4 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA p450 PF00067.20 001288012.1_48624001_2 - 1.9e-73 247.7 0.0 2.5e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3700 PF12481.6 001288461.1_48622001_1 - 9e-98 326.1 0.0 1.1e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 Aluminium induced protein GATase_7 PF13537.4 001288461.1_48622001_1 - 5.6e-11 42.3 0.0 8.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001288461.1_48622001_1 - 2.3e-07 30.9 0.0 3.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain SNF2_assoc PF08455.8 001288461.1_48622001_1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated UQ_con PF00179.24 001288460.1_48622001_1 - 2.7e-43 146.8 0.0 3.6e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.29 001288460.1_48622001_1 - 1.6e-10 40.5 0.1 2.8e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.4 001288460.1_48622001_1 - 7e-05 22.4 0.0 0.00051 19.6 0.0 1.9 1 1 1 2 2 2 1 Prokaryotic E2 family B UBA_4 PF14555.4 001288460.1_48622001_1 - 0.019 14.7 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 UBA-like domain RWD PF05773.20 001288460.1_48622001_1 - 0.051 13.7 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain AAA PF00004.27 001288015.1_48624001_1 - 1.2e-42 145.4 0.0 1.9e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 001288015.1_48624001_1 - 6.7e-07 29.7 0.0 0.00034 20.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.10 001288015.1_48624001_1 - 2.8e-06 26.6 0.0 5.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.12 001288015.1_48624001_1 - 5.8e-06 26.2 0.1 9.3e-05 22.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.12 001288015.1_48624001_1 - 3.8e-05 23.7 0.0 0.00011 22.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.4 001288015.1_48624001_1 - 7.9e-05 22.8 0.1 0.026 14.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain Prot_ATP_ID_OB PF16450.3 001288015.1_48624001_1 - 0.00057 19.3 1.5 0.0011 18.3 0.1 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB/ID domain DUF815 PF05673.11 001288015.1_48624001_1 - 0.0017 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.4 001288015.1_48624001_1 - 0.0024 18.3 0.0 0.0067 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.11 001288015.1_48624001_1 - 0.0033 16.3 0.0 0.0054 15.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001288015.1_48624001_1 - 0.005 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.19 001288015.1_48624001_1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.20 001288015.1_48624001_1 - 0.0063 16.7 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.4 001288015.1_48624001_1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.15 001288015.1_48624001_1 - 0.013 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001288015.1_48624001_1 - 0.013 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.4 001288015.1_48624001_1 - 0.014 15.4 0.0 0.069 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.9 001288015.1_48624001_1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.24 001288015.1_48624001_1 - 0.029 14.0 0.0 0.075 12.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.4 001288015.1_48624001_1 - 0.042 14.0 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.10 001288015.1_48624001_1 - 0.044 13.6 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.4 001288015.1_48624001_1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.11 001288015.1_48624001_1 - 0.057 12.6 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.4 001288015.1_48624001_1 - 0.058 13.0 0.3 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.25 001288015.1_48624001_1 - 0.059 13.8 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.16 001288015.1_48624001_1 - 0.073 12.8 0.0 0.39 10.5 0.0 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.4 001288015.1_48624001_1 - 0.097 12.3 0.3 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.4 001288015.1_48624001_1 - 0.12 11.8 0.2 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain DnaJ_CXXCXGXG PF00684.17 001288241.1_48621001_1 - 0.00093 19.4 12.9 0.00093 19.4 12.9 2.0 2 1 0 2 2 2 1 DnaJ central domain Glyco_hydro_31 PF01055.24 001288463.1_48627001_3 - 7.1e-148 493.3 0.3 1.2e-147 492.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.3 001288463.1_48627001_3 - 2.6e-37 127.4 0.2 5.4e-37 126.4 0.2 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.4 001288463.1_48627001_3 - 2.4e-08 34.0 1.7 4.5e-07 30.0 0.5 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like Pollen_allerg_1 PF01357.19 001288462.1_48623001_2 - 4.7e-27 93.7 0.0 8e-27 93.0 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001288462.1_48623001_2 - 3e-18 65.7 0.2 7.1e-18 64.5 0.2 1.7 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.15 001288462.1_48623001_2 - 0.021 14.6 0.2 0.044 13.5 0.2 1.5 1 0 0 1 1 1 0 Barwin family 1-cysPrx_C PF10417.7 001288462.1_48623001_2 - 0.14 11.9 0.4 0.28 10.9 0.4 1.4 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Pkinase PF00069.23 001288016.1_48623001_1 - 1.5e-73 247.3 0.0 1.9e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288016.1_48623001_1 - 5.6e-32 110.9 0.0 7.6e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.18 001288016.1_48623001_1 - 0.0036 16.8 0.1 0.0068 15.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.21 001288016.1_48623001_1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.12 001288016.1_48623001_1 - 0.017 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HABP4_PAI-RBP1 PF04774.13 001288465.1_48623001_1 - 1.5e-28 99.8 16.3 1.5e-28 99.8 16.3 3.3 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family Stm1_N PF09598.8 001288465.1_48623001_1 - 1.3e-20 73.9 5.7 1.3e-20 73.9 5.7 3.5 3 1 1 4 4 4 1 Stm1 Spore_III_AF PF09581.8 001288465.1_48623001_1 - 0.051 13.5 7.5 0.074 12.9 7.5 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) V_ATPase_I PF01496.17 001288465.1_48623001_1 - 3.2 5.4 4.5 3.9 5.1 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sigma70_ner PF04546.11 001288465.1_48623001_1 - 8.2 6.1 17.6 2.6 7.7 14.8 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Ldh_1_N PF00056.21 001288017.1_48623001_3 - 8.4e-48 161.9 0.0 1.2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001288017.1_48623001_3 - 1.6e-40 138.7 0.0 2.6e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.17 001288017.1_48623001_3 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.14 001288017.1_48623001_3 - 0.08 12.4 0.1 8.5 5.8 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase HLH PF00010.24 001288018.1_48622001_1 - 8.7e-08 31.9 0.3 1.7e-07 31.0 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CDK2AP PF09806.7 001288018.1_48622001_1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein AAA_11 PF13086.4 001288018.1_48622001_1 - 0.061 12.9 0.3 0.098 12.2 0.3 1.4 1 1 0 1 1 1 0 AAA domain SesA PF17107.3 001288018.1_48622001_1 - 0.13 12.4 0.6 8.5 6.5 0.8 2.3 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Glyco_hydro_14 PF01373.15 001288243.1_48624001_1 - 4.1e-164 546.2 0.0 4.9e-164 545.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Ribosomal_L32p PF01783.21 001288467.1_48621001_1 - 8.9e-11 41.7 1.1 1.3e-10 41.2 1.1 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family AUX_IAA PF02309.14 001288469.1_48622001_1 - 1.7e-85 286.6 0.1 2.5e-85 286.1 0.1 1.2 1 0 0 1 1 1 1 AUX/IAA family Ribosomal_60s PF00428.17 001288246.1_48622001_2 - 6.8e-26 90.5 3.6 8.9e-26 90.2 3.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PI-PLC-X PF00388.17 001288471.1_48625001_2 - 5.9e-49 165.3 0.0 1.2e-48 164.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.17 001288471.1_48625001_2 - 2.7e-28 98.5 0.0 4.9e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.28 001288471.1_48625001_2 - 2.4e-11 43.7 0.0 4.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.9 001288471.1_48625001_2 - 1e-05 25.8 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like DUF2650 PF10853.6 001288021.1_48624001_1 - 9 6.0 7.8 3 7.5 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2650) Terpene_synth_C PF03936.14 001288021.1_48624001_3 - 3.3e-102 341.3 5.7 5.2e-102 340.7 5.7 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001288021.1_48624001_3 - 1.7e-56 190.8 1.5 2.9e-56 190.0 1.5 1.4 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain DUF3526 PF12040.6 001288021.1_48624001_3 - 0.034 14.6 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) Glyco_hydro_77 PF02446.15 001288247.1_48627001_1 - 4e-151 503.9 1.9 5.1e-151 503.5 1.9 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.17 001288247.1_48627001_1 - 3.4e-31 106.9 0.0 9.6e-21 73.4 0.0 2.6 2 0 0 2 2 2 2 Starch binding domain Gln-synt_C PF00120.22 001288248.1_48624001_1 - 2.1e-15 56.5 0.0 8.2e-10 38.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001288248.1_48624001_1 - 2.5e-11 43.0 0.0 4.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain S10_plectin PF03501.13 001288249.1_48622001_1 - 4.8e-43 145.0 0.3 6.2e-43 144.7 0.3 1.1 1 0 0 1 1 1 1 Plectin/S10 domain CBFD_NFYB_HMF PF00808.21 001288023.1_48622001_1 - 6e-27 93.6 0.1 8.4e-27 93.1 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001288023.1_48622001_1 - 0.012 15.9 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001288023.1_48622001_1 - 0.036 14.1 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Ferritin PF00210.22 001288475.1_48623001_2 - 1.1e-32 112.7 5.0 1.5e-32 112.3 5.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Glyco_hydro_31 PF01055.24 001288476.1_48626001_2 - 7.9e-145 483.3 5.3 9.8e-145 482.9 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.4 001288476.1_48626001_2 - 4e-22 78.2 0.1 1.8e-20 72.9 0.1 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.2 001288476.1_48626001_2 - 0.0033 17.5 0.0 0.0092 16.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Ribosomal_S6e PF01092.17 001288025.1_48623001_1 - 2.5e-58 195.4 0.3 5.2e-58 194.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e UQ_con PF00179.24 001288251.1_48622001_1 - 3.1e-51 172.6 0.0 4e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001288251.1_48622001_1 - 0.00018 21.1 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001288251.1_48622001_1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain RRM_1 PF00076.20 001288479.1_48623001_1 - 1.9e-31 107.6 0.0 3.9e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001288479.1_48623001_1 - 0.003 17.5 0.0 0.008 16.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif DUF2457 PF10446.7 001288479.1_48623001_1 - 0.39 9.7 17.5 0.55 9.2 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cytokin-bind PF09265.8 001288028.1_48624001_1 - 7.8e-122 405.9 0.5 9.7e-122 405.6 0.5 1.1 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 001288028.1_48624001_1 - 3.8e-22 78.4 0.6 6.5e-22 77.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Epimerase PF01370.19 001288480.1_48623001_1 - 1.1e-26 93.7 0.0 1.8e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001288480.1_48623001_1 - 1.7e-18 66.5 0.0 2.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.3 001288480.1_48623001_1 - 1.1e-16 61.1 0.0 2e-16 60.2 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 001288480.1_48623001_1 - 1.1e-15 57.9 0.0 1.7e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001288480.1_48623001_1 - 2.1e-13 49.9 0.0 2.1e-12 46.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.11 001288480.1_48623001_1 - 8.9e-10 38.4 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.8 001288480.1_48623001_1 - 7.4e-07 29.1 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.23 001288480.1_48623001_1 - 3e-05 23.4 0.0 0.00012 21.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.13 001288480.1_48623001_1 - 8.9e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001288480.1_48623001_1 - 0.067 12.2 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.23 001288027.1_48624001_1 - 1.2e-45 155.8 0.0 1.5e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288027.1_48624001_1 - 5.6e-45 153.5 0.0 7.4e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRRNT_2 PF08263.10 001288027.1_48624001_1 - 9.7e-11 41.6 1.7 9.7e-11 41.6 1.7 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.4 001288027.1_48624001_1 - 2.2e-07 30.4 16.9 0.002 17.7 5.3 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.5 001288027.1_48624001_1 - 3.4e-07 30.3 19.9 0.0014 18.9 4.0 3.5 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) APH PF01636.21 001288027.1_48624001_1 - 0.00076 19.3 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family LRR_1 PF00560.31 001288027.1_48624001_1 - 0.0037 17.4 17.9 1.3 9.6 0.6 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat Kinase-like PF14531.4 001288027.1_48624001_1 - 0.065 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SKG6 PF08693.8 001288027.1_48624001_1 - 0.077 12.3 0.9 0.17 11.2 0.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ADH_N PF08240.10 001288031.1_48623001_3 - 7.6e-25 86.8 1.4 1.4e-24 85.9 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.24 001288031.1_48623001_3 - 3.1e-24 85.2 0.1 5.4e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.16 001288031.1_48623001_3 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.12 001288031.1_48623001_3 - 0.0039 16.7 0.1 0.0061 16.0 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.17 001288031.1_48623001_3 - 0.006 15.8 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.4 001288031.1_48623001_3 - 0.024 15.6 0.0 0.054 14.4 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.19 001288031.1_48623001_3 - 0.074 12.2 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Reo_sigma1 PF01664.14 001288031.1_48623001_3 - 0.19 10.8 0.2 0.5 9.5 0.0 1.7 2 0 0 2 2 2 0 Reovirus viral attachment protein sigma 1 VPEP PF07589.9 001288031.1_48623001_3 - 0.26 11.3 1.0 0.67 10.0 1.0 1.7 1 0 0 1 1 1 0 PEP-CTERM motif ATP-sulfurylase PF01747.15 001288481.1_48624001_3 - 5.5e-65 218.7 0.0 6.8e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.4 001288481.1_48624001_3 - 5.9e-46 155.9 0.0 9.4e-46 155.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Pkinase PF00069.23 001288256.1_48624001_2 - 8.1e-71 238.3 0.0 1.2e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288256.1_48624001_2 - 8.7e-34 116.8 0.0 1.3e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001288256.1_48624001_2 - 0.00049 19.4 0.0 0.001 18.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.12 001288256.1_48624001_2 - 0.0027 16.9 0.2 0.0043 16.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BURP PF03181.13 001288484.1_48623001_2 - 3.8e-88 294.5 2.3 4.8e-88 294.2 2.3 1.1 1 0 0 1 1 1 1 BURP domain Sushi_2 PF09014.8 001288484.1_48623001_2 - 0.074 12.9 1.0 0.13 12.1 1.0 1.4 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain UQ_con PF00179.24 001288257.1_48622001_3 - 2.1e-38 131.0 0.0 2.7e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme WRKY PF03106.13 001288485.1_48623001_1 - 3.9e-22 78.2 11.0 3.9e-22 78.2 11.0 1.8 2 0 0 2 2 2 1 WRKY DNA -binding domain MRF_C2 PF13888.4 001288485.1_48623001_1 - 0.62 9.8 6.0 0.46 10.3 3.2 1.9 1 1 1 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 UQ_con PF00179.24 001288486.1_48622001_1 - 7.4e-14 51.5 0.0 9.5e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Meth_synt_2 PF01717.16 001288487.1_48626001_3 - 7.9e-161 534.6 0.0 1.4e-156 520.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.10 001288487.1_48626001_3 - 2.6e-127 424.5 0.0 4.7e-119 397.4 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain TM1586_NiRdase PF14512.4 001288487.1_48626001_3 - 0.0098 15.3 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 1 Putative TM nitroreductase LCD1 PF09798.7 001288487.1_48626001_3 - 0.3 9.4 1.4 0.46 8.8 1.4 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Pectinesterase PF01095.17 001288040.1_48625001_1 - 7.9e-150 497.4 4.3 1.1e-149 497.0 4.3 1.1 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.13 001288040.1_48625001_1 - 1.8e-27 96.4 3.7 2.8e-27 95.7 3.7 1.3 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor PhoU_div PF01865.14 001288040.1_48625001_1 - 0.066 12.4 0.4 0.12 11.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 APG17 PF04108.10 001288040.1_48625001_1 - 0.067 12.2 1.2 0.094 11.7 1.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Abhydrolase_1 PF00561.18 001288488.1_48623001_1 - 3.9e-20 72.4 0.0 1.6e-19 70.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001288488.1_48623001_1 - 1.7e-19 71.2 0.4 2.4e-19 70.7 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001288488.1_48623001_1 - 3.2e-13 49.4 0.0 8.1e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.9 001288488.1_48623001_1 - 0.0075 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.5 001288488.1_48623001_1 - 0.014 14.1 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme NAM PF02365.13 001288041.1_48623001_2 - 4.3e-28 97.9 0.1 7.9e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein Put_DNA-bind_N PF06971.11 001288041.1_48623001_3 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Transferase PF02458.13 001288261.1_48623001_1 - 2e-102 343.0 0.0 2.4e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Transferase family RRM_1 PF00076.20 001288490.1_48624001_1 - 2.3e-48 161.8 0.0 8.7e-19 67.0 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001288490.1_48624001_1 - 0.00014 21.3 0.0 0.042 13.3 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001288490.1_48624001_1 - 0.00035 20.5 0.1 5.1 7.1 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.4 001288490.1_48624001_1 - 0.0062 16.7 0.1 4.4 7.4 0.0 3.6 3 1 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.3 001288490.1_48624001_1 - 0.057 13.2 0.0 32 4.3 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif Methyltransf_11 PF08241.10 001288262.1_48623001_1 - 5.1e-21 75.0 0.0 8.5e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001288262.1_48623001_1 - 6.9e-19 68.2 0.0 1.3e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 001288262.1_48623001_1 - 2.8e-15 56.5 0.0 4.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001288262.1_48623001_1 - 2.3e-14 53.3 0.0 3.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.18 001288262.1_48623001_1 - 5.8e-13 48.6 0.0 8.2e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.10 001288262.1_48623001_1 - 9.6e-09 35.7 0.0 1.7e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.16 001288262.1_48623001_1 - 8.4e-06 25.1 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NAS PF03059.14 001288262.1_48623001_1 - 0.0097 15.1 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Nicotianamine synthase protein MetW PF07021.10 001288262.1_48623001_1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.4 001288262.1_48623001_1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.16 001288262.1_48623001_1 - 0.027 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.12 001288262.1_48623001_1 - 0.033 13.6 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TSLP PF15216.4 001288262.1_48623001_1 - 0.062 13.4 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Thymic stromal lymphopoietin Methyltransf_20 PF12147.6 001288262.1_48623001_1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Filament_head PF04732.12 001288262.1_48623001_1 - 0.16 12.7 3.6 0.9 10.3 0.0 2.6 2 1 0 2 2 2 0 Intermediate filament head (DNA binding) region zf-DNL PF05180.10 001288042.1_48622001_1 - 2.1e-16 59.5 2.1 3.4e-16 58.8 2.1 1.3 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.16 001288042.1_48622001_1 - 4.8 7.0 6.7 16 5.3 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Glycolytic PF00274.17 001288043.1_48623001_3 - 2.8e-155 516.2 0.0 3.2e-155 516.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF4922 PF16269.3 001288264.1_48624001_1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) GTP_EFTU PF00009.25 001288491.1_48624001_1 - 1.5e-51 174.6 0.1 3.7e-51 173.3 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001288491.1_48624001_1 - 1.9e-38 131.1 0.0 1.9e-38 131.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001288491.1_48624001_1 - 4.7e-14 52.4 0.3 1.2e-13 51.1 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001288491.1_48624001_1 - 0.01 15.8 0.2 0.038 13.9 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001288491.1_48624001_1 - 0.028 14.3 1.2 0.055 13.3 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 SRPRB PF09439.8 001288491.1_48624001_1 - 0.051 12.9 0.6 0.35 10.2 0.0 2.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FAD_binding_4 PF01565.21 001288265.1_48624001_1 - 9.3e-15 54.5 0.1 1.5e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Methyltransf_3 PF01596.15 001288045.1_48622001_1 - 4e-93 310.3 0.0 4.6e-93 310.1 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001288045.1_48622001_1 - 3.4e-13 50.4 0.0 5.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001288045.1_48622001_1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001288045.1_48622001_1 - 0.0014 19.2 0.0 0.0029 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 001288045.1_48622001_1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PXB PF12828.5 001288045.1_48622001_1 - 0.078 12.8 0.2 0.66 9.8 0.2 2.0 1 1 0 1 1 1 0 PX-associated Ribosomal_S19 PF00203.19 001288044.1_48622001_1 - 5.7e-33 112.5 0.4 5.7e-33 112.5 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein S19 OAD_gamma PF04277.11 001288044.1_48622001_3 - 2 8.9 7.6 3.1 8.3 7.6 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Metalloenzyme PF01676.16 001288266.1_48624001_2 - 8e-100 333.1 0.0 9.3e-100 332.9 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.11 001288266.1_48624001_2 - 1.1e-59 201.4 0.0 1.4e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.20 001288266.1_48624001_2 - 0.087 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Lyase_1 PF00206.18 001288493.1_48624001_3 - 1e-113 379.7 0.0 1.3e-113 379.4 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.7 001288493.1_48624001_3 - 6e-25 87.3 0.0 1.3e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus PyrI PF01948.16 001288493.1_48624001_3 - 0.001 19.2 0.1 0.002 18.2 0.1 1.4 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain Proteasome PF00227.24 001288267.1_48623001_3 - 2e-55 187.1 0.0 5.4e-55 185.7 0.0 1.6 1 1 1 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.7 001288267.1_48623001_3 - 6.1e-09 35.3 0.6 1.9e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribosom_S12_S23 PF00164.23 001288047.1_48622001_3 - 2.6e-59 198.5 1.5 3.3e-59 198.3 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Auxin_repressed PF05564.10 001288494.1_48622001_1 - 3.9e-09 37.1 0.3 6.8e-09 36.3 0.3 1.4 1 0 0 1 1 1 1 Dormancy/auxin associated protein OAD_gamma PF04277.11 001288494.1_48622001_2 - 3.6 8.1 4.7 5.8 7.4 4.7 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain eIF-5_eIF-2B PF01873.15 001288268.1_48623001_3 - 3.5e-40 136.4 0.0 5.9e-40 135.7 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.10 001288268.1_48623001_3 - 0.05 13.0 0.2 0.13 11.7 0.2 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Arf PF00025.19 001288496.1_48622001_1 - 2.3e-79 264.8 0.1 2.8e-79 264.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001288496.1_48622001_1 - 2e-13 50.1 0.0 2.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.11 001288496.1_48622001_1 - 2.1e-13 50.4 0.0 3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.18 001288496.1_48622001_1 - 3e-12 46.2 0.9 2e-08 33.6 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.20 001288496.1_48622001_1 - 5.5e-12 45.4 0.0 6.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.10 001288496.1_48622001_1 - 6.1e-10 38.7 0.0 7.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001288496.1_48622001_1 - 0.00012 22.0 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 001288496.1_48622001_1 - 0.013 14.7 0.5 0.022 13.9 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Ribosomal_L5_C PF00673.19 001288050.1_48622001_1 - 8.4e-21 73.8 0.0 1.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.17 001288050.1_48622001_1 - 1.5e-20 73.1 0.0 2.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 UQ_con PF00179.24 001288051.1_48621001_1 - 3.3e-54 182.2 0.0 3.8e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001288051.1_48621001_1 - 0.00092 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.4 001288051.1_48621001_1 - 0.0013 18.3 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.11 001288051.1_48621001_1 - 0.024 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain G-gamma PF00631.20 001288051.1_48621001_1 - 0.074 12.9 0.7 0.22 11.4 0.1 2.0 2 1 0 2 2 2 0 GGL domain ADK PF00406.20 001288499.1_48623001_3 - 1.3e-22 80.4 0.0 1.9e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.4 001288499.1_48623001_3 - 4.1e-09 36.8 0.0 6.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Alpha-amyl_C2 PF07821.10 001288053.1_48623001_1 - 6.7e-23 80.6 0.2 1.3e-22 79.6 0.2 1.5 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.22 001288053.1_48623001_1 - 4.1e-12 46.2 0.0 9.1e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Atg8 PF02991.14 001288500.1_48621001_1 - 7.7e-44 148.0 0.0 9e-44 147.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.11 001288500.1_48621001_1 - 1.6e-06 28.3 0.0 2.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Acetyltransf_1 PF00583.23 001288270.1_48623001_2 - 2e-16 60.1 0.0 3.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.5 001288270.1_48623001_2 - 4.6e-10 39.7 0.1 7.4e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.5 001288270.1_48623001_2 - 2.3e-09 37.1 0.1 3.6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.8 001288270.1_48623001_2 - 4.1e-06 26.5 0.1 7.3e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.5 001288270.1_48623001_2 - 1.3e-05 25.8 0.0 1.9e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.4 001288270.1_48623001_2 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.5 001288270.1_48623001_2 - 0.014 15.3 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TAL_FSA PF00923.17 001288054.1_48623001_3 - 2.3e-75 253.5 0.0 2.6e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase ACBP PF00887.17 001288055.1_48621001_1 - 9.6e-28 96.1 0.4 1.2e-27 95.8 0.4 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein RRM_1 PF00076.20 001288501.1_48623001_3 - 4.1e-57 189.8 0.0 4.4e-19 67.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001288501.1_48623001_3 - 1.3e-09 37.6 0.0 4.6e-06 26.1 0.0 3.3 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001288501.1_48623001_3 - 2.2e-09 37.1 0.0 5.6e-05 23.1 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.9 001288501.1_48623001_3 - 8.9e-08 32.0 2.5 0.0002 21.2 0.0 3.5 4 0 0 4 4 4 2 RNA binding motif RRM_occluded PF16842.3 001288501.1_48623001_3 - 0.013 15.2 0.0 0.52 10.1 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif SET_assoc PF11767.6 001288501.1_48623001_3 - 0.041 13.4 0.2 32 4.1 0.1 3.3 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated DUF1866 PF08952.9 001288501.1_48623001_3 - 0.13 12.0 0.1 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Pollen_allerg_1 PF01357.19 001288501.1_48623001_3 - 2.1 8.3 6.2 11 6.0 5.6 2.4 2 0 0 2 2 2 0 Pollen allergen NDUFB10 PF10249.7 001288501.1_48623001_3 - 2.4 8.6 11.5 4.2 7.8 0.4 2.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 PHM7_cyt PF14703.4 001288501.1_48623001_3 - 6.9 6.7 9.8 5.1 7.2 0.0 4.0 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter CTD_bind PF04818.11 001288502.1_48625001_1 - 3.6e-13 50.0 0.1 1.6e-12 47.9 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Surp PF01805.18 001288502.1_48625001_1 - 1.7e-12 47.0 0.2 3.9e-12 45.9 0.2 1.6 1 0 0 1 1 1 1 Surp module Med3 PF11593.6 001288502.1_48625001_1 - 1.6 7.7 8.4 3.4 6.6 8.4 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L13e PF01294.16 001288274.1_48622001_1 - 8.7e-80 266.7 3.8 1.1e-79 266.4 3.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L44 PF00935.17 001288058.1_48622001_2 - 3e-33 114.0 9.1 3e-33 114.0 9.1 2.3 3 0 0 3 3 3 1 Ribosomal protein L44 AIG1 PF04548.14 001288503.1_48623001_1 - 1.7e-37 128.7 0.0 5.7e-37 127.0 0.0 1.8 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.21 001288503.1_48623001_1 - 4.3e-12 46.0 0.0 7.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001288503.1_48623001_1 - 7.6e-08 32.3 0.1 4.8e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.21 001288503.1_48623001_1 - 1.5e-05 25.0 2.2 0.1 12.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.16 001288503.1_48623001_1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.16 001288503.1_48623001_1 - 0.0031 16.7 0.1 0.0068 15.5 0.1 1.6 1 1 0 1 1 1 1 Septin AAA_16 PF13191.4 001288503.1_48623001_1 - 0.0061 16.8 1.0 0.022 15.0 0.9 2.0 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.9 001288503.1_48623001_1 - 0.025 13.6 0.0 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Gtr1_RagA PF04670.10 001288503.1_48623001_1 - 0.062 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.24 001288503.1_48623001_1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.20 001288503.1_48623001_1 - 0.082 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain GTP_EFTU PF00009.25 001288503.1_48623001_1 - 0.13 11.6 0.1 1.4 8.3 0.0 2.3 1 1 2 3 3 3 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.4 001288503.1_48623001_1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.11 001288503.1_48623001_1 - 0.16 11.0 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ribosomal_L24e PF01246.18 001288275.1_48622001_3 - 1.7e-29 101.7 0.7 4.2e-29 100.4 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Spore_coat_CotO PF14153.4 001288275.1_48622001_3 - 0.23 11.2 6.8 0.31 10.8 6.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF106 PF01956.14 001288275.1_48622001_3 - 9.3 5.8 8.9 9.6 5.8 3.9 2.1 1 1 1 2 2 2 0 Integral membrane protein DUF106 NTP_transferase PF00483.21 001288276.1_48623001_1 - 7.8e-53 179.5 0.0 1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.5 001288276.1_48623001_1 - 6.7e-10 39.4 0.0 8.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.22 001288276.1_48623001_1 - 3.4e-08 32.8 9.4 1.7e-07 30.6 1.2 3.2 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.3 001288276.1_48623001_1 - 0.0048 15.0 0.4 0.0068 14.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.4 001288276.1_48623001_1 - 0.0074 15.9 6.8 0.014 15.0 4.0 2.9 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF257 PF03192.11 001288276.1_48623001_1 - 0.033 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 IspD PF01128.17 001288276.1_48623001_1 - 0.099 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.17 001288276.1_48623001_1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.10 001288276.1_48623001_1 - 0.16 10.8 0.0 2.1 7.2 0.0 2.0 2 0 0 2 2 2 0 L-fucokinase Tubulin PF00091.23 001288277.1_48624001_1 - 4.6e-67 225.9 0.0 7.3e-67 225.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001288277.1_48624001_1 - 1.4e-40 138.3 0.2 2e-40 137.8 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001288277.1_48624001_1 - 0.0018 17.8 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.4 001288277.1_48624001_1 - 0.0025 16.9 0.1 0.0066 15.5 0.0 1.6 2 0 0 2 2 2 1 Tubulin like Misat_Tub_SegII PF10644.7 001288277.1_48624001_1 - 0.0073 16.5 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain TIM PF00121.16 001288506.1_48622001_1 - 4.9e-87 291.2 0.0 5.8e-87 291.0 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MRP-S23 PF10484.7 001288061.1_48623001_3 - 0.024 14.7 1.2 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 HTH_Tnp_Mu_2 PF09039.9 001288061.1_48623001_3 - 0.07 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain MRP-S25 PF13741.4 001288061.1_48623001_3 - 0.078 12.4 2.1 0.091 12.2 0.4 1.9 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S25 2OG-FeII_Oxy PF03171.18 001288279.1_48623001_1 - 4.3e-27 94.4 0.0 6.8e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001288279.1_48623001_1 - 3e-12 47.2 0.1 5.9e-12 46.3 0.1 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal KaiA PF07688.10 001288279.1_48623001_1 - 0.062 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 KaiA C-terminal domain Mlo PF03094.13 001318704.1_48624001_1 - 1.3e-217 722.8 14.6 4.7e-216 717.6 14.6 2.0 1 1 0 1 1 1 1 Mlo family EVC2_like PF12297.6 001318704.1_48624001_1 - 0.019 13.5 0.0 0.035 12.7 0.0 1.4 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein CAF1C_H4-bd PF12265.6 001288507.1_48624001_3 - 2.2e-15 56.5 0.1 5.5e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.30 001288507.1_48624001_3 - 1.4e-11 44.6 14.1 1.7e-05 25.3 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat S-antigen PF05756.9 001288507.1_48624001_3 - 0.5 10.5 1.8 1.2 9.3 1.8 1.6 1 0 0 1 1 1 0 S-antigen protein Auxin_repressed PF05564.10 001288280.1_48621001_1 - 2.8e-53 179.5 2.2 3.2e-53 179.3 2.2 1.0 1 0 0 1 1 1 1 Dormancy/auxin associated protein MFS_2 PF13347.4 001288509.1_48624001_1 - 7.2e-11 41.1 18.0 3.2e-10 39.0 3.9 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.13 001288509.1_48624001_1 - 3.5e-06 26.1 0.4 3.5e-06 26.1 0.4 2.3 2 0 0 2 2 2 2 PUCC protein DUF2070 PF09843.7 001288509.1_48624001_1 - 0.66 8.1 10.7 0.079 11.1 4.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Pkinase PF00069.23 001288510.1_48623001_1 - 1.9e-71 240.4 0.0 2.3e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288510.1_48623001_1 - 3.9e-33 114.7 0.0 5.3e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001288510.1_48623001_1 - 0.002 17.4 0.0 0.019 14.1 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.18 001288510.1_48623001_1 - 0.0029 17.1 0.2 0.074 12.5 0.0 2.4 3 0 0 3 3 3 1 Choline/ethanolamine kinase APH PF01636.21 001288510.1_48623001_1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family UQ_con PF00179.24 001288282.1_48622001_2 - 4.6e-48 162.3 0.0 6e-48 161.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001288282.1_48622001_2 - 0.0071 15.9 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.11 001288282.1_48622001_2 - 0.029 14.1 0.0 0.054 13.2 0.0 1.4 1 1 0 1 1 1 0 UEV domain Proteasome PF00227.24 001288511.1_48622001_2 - 6.4e-62 208.3 0.1 8.1e-62 208.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001288511.1_48622001_2 - 8.7e-14 50.7 0.1 1.5e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Allene_ox_cyc PF06351.9 001288283.1_48622001_1 - 1e-88 295.3 0.1 1.5e-88 294.8 0.1 1.2 1 0 0 1 1 1 1 Allene oxide cyclase Dirigent PF03018.12 001288283.1_48622001_1 - 0.0015 18.3 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Dirigent-like protein MIP PF00230.18 001288067.1_48622001_2 - 6.5e-51 173.1 17.9 8e-51 172.8 17.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pkinase_Tyr PF07714.15 001288513.1_48627001_2 - 1.4e-42 145.7 0.0 1.9e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001288513.1_48627001_2 - 1.3e-38 132.7 0.0 1.7e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.4 001288513.1_48627001_2 - 5e-09 35.7 22.8 1.4e-07 31.0 5.3 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 001288513.1_48627001_2 - 1.1e-05 25.6 21.8 0.0088 16.3 1.4 4.6 1 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001288513.1_48627001_2 - 0.0043 17.2 15.2 9.5 7.0 1.2 6.7 4 2 0 4 4 4 1 Leucine Rich Repeat DUF912 PF06024.10 001288513.1_48627001_2 - 0.033 14.3 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC1 PF03109.14 001288513.1_48627001_2 - 0.034 14.2 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 ABC1 family LRR_6 PF13516.4 001288513.1_48627001_2 - 1.9 8.6 14.3 2 8.6 0.3 4.5 5 0 0 5 5 5 0 Leucine Rich repeat GAGA_bind PF06217.10 001288284.1_48623001_2 - 5.3e-80 269.7 2.1 7e-80 269.3 2.1 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family DUF390 PF04094.12 001288284.1_48623001_2 - 0.094 10.9 5.5 0.14 10.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF4200 PF13863.4 001288284.1_48623001_2 - 3.2 8.0 7.2 2.5 8.4 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tim17 PF02466.17 001288069.1_48623001_3 - 2.2e-24 85.6 5.1 2.2e-24 85.6 5.1 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF347 PF03988.10 001288069.1_48623001_3 - 0.025 14.6 2.8 0.078 13.0 2.8 1.8 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) UQ_con PF00179.24 001288514.1_48622001_2 - 6.5e-15 54.9 0.0 8.4e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MIP PF00230.18 001288515.1_48622001_1 - 7.1e-38 130.4 15.1 9.3e-38 130.1 15.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein ODV-E18 PF10717.7 001288515.1_48622001_1 - 0.67 9.7 7.3 0.26 11.0 3.5 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Vma12 PF11712.6 001288515.1_48622001_1 - 2.2 8.2 6.0 1.6 8.6 1.3 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RNase_PH PF01138.19 001288516.1_48623001_3 - 2.9e-20 73.0 0.1 5.5e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.13 001288516.1_48623001_3 - 1.1e-05 25.2 0.0 2.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Arf PF00025.19 001288071.1_48622001_2 - 1.7e-64 216.3 0.0 2.1e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.18 001288071.1_48622001_2 - 1.2e-11 44.2 0.1 6.6e-08 32.0 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.11 001288071.1_48622001_2 - 1.6e-08 34.6 0.0 3.1e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.8 001288071.1_48622001_2 - 1.1e-07 31.3 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001288071.1_48622001_2 - 4.1e-07 30.0 0.0 5.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.20 001288071.1_48622001_2 - 1.2e-06 28.0 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.10 001288071.1_48622001_2 - 0.0037 16.5 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.7 001288071.1_48622001_2 - 0.0057 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation PfkB PF00294.22 001288518.1_48623001_1 - 6.5e-34 117.5 0.0 1.1e-33 116.7 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase WRKY PF03106.13 001288072.1_48623001_3 - 3.9e-27 94.3 0.2 3.9e-27 94.3 0.2 1.7 2 0 0 2 2 2 1 WRKY DNA -binding domain Plant_zn_clust PF10533.7 001288072.1_48623001_3 - 4.7e-18 64.7 11.4 1.1e-17 63.6 11.4 1.7 1 0 0 1 1 1 1 Plant zinc cluster domain FLYWCH PF04500.14 001288072.1_48623001_3 - 0.05 13.6 0.0 0.05 13.6 0.0 1.8 2 0 0 2 2 2 0 FLYWCH zinc finger domain 14-3-3 PF00244.18 001288288.1_48623001_1 - 2.9e-105 350.6 3.0 4.5e-105 349.9 3.0 1.3 1 0 0 1 1 1 1 14-3-3 protein MIF PF01187.16 001288289.1_48621001_1 - 3.6e-23 81.9 0.0 4e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) p450 PF00067.20 001288290.1_48624001_2 - 1.3e-65 221.8 0.0 1.5e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CBM_48 PF02922.16 001288291.1_48626001_2 - 4.9e-14 52.3 0.0 1.1e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.22 001288291.1_48626001_2 - 6e-13 48.9 7.8 1.1e-11 44.8 0.0 3.7 2 1 0 2 2 2 1 Alpha amylase, catalytic domain HABP4_PAI-RBP1 PF04774.13 001288520.1_48623001_2 - 1.8e-28 99.6 8.5 1.8e-28 99.6 8.5 2.4 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.8 001288520.1_48623001_2 - 5.8e-20 71.8 5.2 5.8e-20 71.8 5.2 3.1 3 0 0 3 3 3 1 Stm1 GRP PF07172.9 001288520.1_48623001_2 - 0.0069 16.9 1.8 0.0069 16.9 1.8 3.8 3 1 1 4 4 4 1 Glycine rich protein family PRP1_N PF06424.10 001288520.1_48623001_2 - 0.75 10.1 11.9 0.075 13.3 5.6 2.1 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal Ribosomal_L24e PF01246.18 001288521.1_48621001_1 - 3.4e-29 100.7 0.6 3.4e-29 100.7 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Spore_coat_CotO PF14153.4 001288521.1_48621001_1 - 0.065 13.0 7.9 0.084 12.7 7.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RF-1 PF00472.18 001288521.1_48621001_1 - 1.7 8.5 10.7 2.3 8.0 3.4 2.2 2 0 0 2 2 2 0 RF-1 domain Presenilin PF01080.15 001288521.1_48621001_1 - 2.1 6.9 4.0 2.3 6.7 4.0 1.0 1 0 0 1 1 1 0 Presenilin TPKR_C2 PF16920.3 001288521.1_48621001_2 - 0.14 12.2 0.8 1.9 8.6 0.1 2.5 3 0 0 3 3 3 0 Tyrosine-protein kinase receptor C2 Ig-like domain Ribosomal_S13_N PF08069.10 001288292.1_48622001_3 - 1e-31 108.6 0.1 1.8e-31 107.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.20 001288292.1_48622001_3 - 1.3e-15 57.2 1.7 1.8e-15 56.7 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PGK PF00162.17 001288522.1_48623001_3 - 5.2e-165 548.8 0.1 6e-165 548.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.9 001288522.1_48623001_3 - 0.15 11.5 0.2 1 8.8 0.1 2.4 3 0 0 3 3 3 0 Propionate catabolism activator Corona_NS1 PF06145.9 001288293.1_48623001_2 - 0.12 11.7 0.2 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 Syntaxin_2 PF14523.4 001288293.1_48623001_3 - 4.4e-30 103.9 7.4 1.1e-29 102.6 1.7 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.17 001288293.1_48623001_3 - 1.5e-16 60.0 0.2 3.8e-16 58.7 0.2 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.23 001288293.1_48623001_3 - 4.4e-06 26.4 12.8 5.7e-05 22.7 12.8 2.3 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.19 001288293.1_48623001_3 - 0.00061 19.5 4.1 0.00061 19.5 4.1 2.3 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.19 001288293.1_48623001_3 - 0.0017 18.0 0.6 0.0033 17.1 0.6 1.5 1 0 0 1 1 1 1 Synaptobrevin Spore_III_AB PF09548.8 001288293.1_48623001_3 - 0.25 11.3 5.8 0.47 10.4 0.1 2.9 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) LXG PF04740.10 001288293.1_48623001_3 - 0.34 10.5 5.8 0.85 9.2 4.4 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily Rifin_STEVOR PF02009.14 001288293.1_48623001_3 - 2.1 8.0 5.8 4.1 7.1 5.8 1.5 1 1 1 2 2 2 0 Rifin/stevor family V-SNARE PF05008.13 001288293.1_48623001_3 - 5.1 7.4 8.6 0.49 10.7 0.6 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Amino_oxidase PF01593.22 001288295.1_48624001_1 - 1.6e-90 304.4 0.0 2e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.4 001288295.1_48624001_1 - 1.6e-09 37.7 0.0 4.1e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.15 001288295.1_48624001_1 - 0.0013 17.9 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.22 001288295.1_48624001_1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Malic_M PF03949.13 001288295.1_48624001_1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain HMA PF00403.24 001288296.1_48622001_2 - 1.1e-07 32.0 0.4 2e-07 31.2 0.4 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Tim54 PF11711.6 001288296.1_48622001_2 - 0.57 8.8 4.5 0.74 8.4 3.7 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 LEA_2 PF03168.11 001289015.1_48622001_1 - 1.5e-14 54.2 0.1 2.1e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein LEA_2 PF03168.11 001289014.1_48622001_1 - 1.1e-14 54.6 0.5 1.9e-14 53.9 0.5 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Tetraspannin PF00335.18 001289014.1_48622001_1 - 0.014 15.1 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF3675 PF12428.6 001289014.1_48622001_1 - 0.04 14.4 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Vac7 PF12751.5 001289014.1_48622001_1 - 0.042 13.2 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Pex14_N PF04695.11 001289014.1_48622001_1 - 0.059 14.0 0.1 0.095 13.3 0.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LEA_2 PF03168.11 001289011.1_48622001_1 - 2.6e-16 59.8 0.7 5.1e-16 58.9 0.7 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein Vac7 PF12751.5 001289011.1_48622001_1 - 0.0085 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 Tetraspannin PF00335.18 001289011.1_48622001_1 - 0.024 14.3 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF3675 PF12428.6 001289011.1_48622001_1 - 0.088 13.3 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) HSP20 PF00011.19 001288681.1_48621001_1 - 1e-32 112.2 3.3 1.2e-32 111.9 3.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.14 001288681.1_48621001_1 - 0.0045 17.9 1.7 0.0071 17.2 0.8 1.7 1 1 1 2 2 2 1 CS domain GvpH PF05455.9 001288681.1_48621001_1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 GvpH Pkinase PF00069.23 001156280.1_53725001_2 - 1.3e-48 165.6 0.0 1.6e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001156280.1_53725001_2 - 6.9e-47 159.8 0.0 9.2e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Stress-antifung PF01657.15 001156280.1_53725001_2 - 1.1e-34 118.8 6.2 6e-20 71.5 1.1 2.4 2 0 0 2 2 2 2 Salt stress response/antifungal APH PF01636.21 001156280.1_53725001_2 - 0.028 14.2 1.9 0.58 9.9 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.12 001156280.1_53725001_2 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_tail_L PF05100.10 001156280.1_53725001_2 - 0.11 11.6 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 Phage minor tail protein L PTS_EIIB PF00367.18 001176350.1_53723001_1 - 0.046 13.1 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 phosphotransferase system, EIIB RRM_1 PF00076.20 001176350.1_53723001_3 - 5.9e-17 61.1 0.0 9.1e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001176350.1_53723001_3 - 0.0015 18.5 0.0 0.004 17.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.4 001176350.1_53723001_3 - 0.035 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PPR_2 PF13041.4 001175878.1_53725001_2 - 2.8e-59 197.0 4.8 7e-14 51.6 0.0 8.3 5 1 4 9 9 9 8 PPR repeat family PPR PF01535.18 001175878.1_53725001_2 - 2.7e-46 152.5 15.6 5.4e-08 32.4 0.0 11.2 11 0 0 11 11 11 10 PPR repeat PPR_1 PF12854.5 001175878.1_53725001_2 - 6.2e-43 144.1 2.6 1.1e-09 37.7 0.0 10.2 10 0 0 10 10 10 7 PPR repeat PPR_3 PF13812.4 001175878.1_53725001_2 - 3.2e-36 123.1 0.0 9.2e-08 31.9 0.0 7.0 5 2 2 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.2 001175878.1_53725001_2 - 1.4e-18 66.9 0.0 8.5e-05 21.9 0.0 4.3 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001175878.1_53725001_2 - 2.6e-06 27.7 0.3 3.6 8.5 0.1 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.4 001175878.1_53725001_2 - 0.00015 22.1 0.0 0.00074 19.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Wzy_C_2 PF11846.6 001175878.1_53725001_2 - 0.019 14.8 0.1 2.4 7.9 0.1 2.6 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal ATP13 PF12921.5 001175878.1_53725001_2 - 0.14 11.9 0.0 5.2 6.8 0.0 3.1 3 1 0 3 3 3 0 Mitochondrial ATPase expression Clathrin PF00637.18 001175878.1_53725001_2 - 0.17 11.6 0.0 3.1 7.5 0.0 2.9 3 1 0 3 3 3 0 Region in Clathrin and VPS Sucrose_synth PF00862.17 001288308.1_48626001_1 - 4.4e-291 965.8 0.0 5.5e-291 965.5 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.18 001288308.1_48626001_1 - 2.7e-30 105.1 0.0 4.8e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001288308.1_48626001_1 - 1.4e-09 38.4 0.0 2.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001288308.1_48626001_1 - 9.3e-05 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_CodY PF08222.9 001288308.1_48626001_1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain Polyketide_cyc2 PF10604.7 001297630.1_48622001_2 - 1.1e-11 45.1 0.1 1.7e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.18 001297630.1_48622001_2 - 1.2e-07 31.9 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Bet_v_1 PF00407.17 001297630.1_48622001_2 - 0.036 13.9 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family AA_permease_2 PF13520.4 001154537.1_53725001_3 - 2.7e-44 151.6 40.3 2.7e-44 151.6 40.3 1.9 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.19 001154537.1_53725001_3 - 2.6e-34 118.5 36.4 2.6e-34 118.5 36.4 2.1 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.4 001154537.1_53725001_3 - 2.8e-16 59.2 5.2 2.8e-16 59.2 5.2 4.2 4 0 0 4 4 4 1 C-terminus of AA_permease Bax1-I PF01027.18 001154537.1_53725001_3 - 2.8 7.6 42.0 1.2 8.8 7.0 3.4 3 0 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 Proteasome PF00227.24 001254851.1_53723001_2 - 1.4e-55 187.7 0.0 1.9e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001254851.1_53723001_2 - 1.1e-14 53.6 0.1 2.1e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature HAD PF12710.5 001153970.2_53724001_3 - 5.1e-13 49.7 2.5 9.4e-13 48.8 2.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.19 001153970.2_53724001_3 - 4.5e-07 29.4 0.0 8.8e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Retrotrans_gag PF03732.15 001301467.1_53725001_3 - 3.5e-17 62.3 2.8 1.2e-16 60.6 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein EPF PF17181.2 001165543.1_53722001_1 - 6.4e-18 64.4 0.2 1.9e-17 62.9 0.2 1.8 1 1 0 1 1 1 1 Epidermal patterning factor proteins Stomagen PF16851.3 001165543.1_53722001_1 - 0.0027 17.5 2.4 0.0067 16.3 2.4 1.6 1 0 0 1 1 1 1 Stomagen MHC2-interact PF09307.8 001151854.1_53721001_3 - 0.052 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 CLIP, MHC2 interacting p450 PF00067.20 001287878.1_48624001_1 - 1e-120 403.5 0.0 1.2e-120 403.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SusD-like PF12741.5 001287878.1_48624001_1 - 0.0027 16.5 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 Susd and RagB outer membrane lipoprotein Flu_B_NS1 PF02942.12 001287878.1_48624001_1 - 0.013 14.4 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) WPP PF13943.4 001288250.1_48624001_1 - 1.6e-34 118.1 1.8 2.3e-34 117.6 0.2 2.1 2 0 0 2 2 2 1 WPP domain LRR_6 PF13516.4 001288250.1_48624001_1 - 3.5e-19 67.0 12.4 0.054 13.4 0.0 9.5 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.5 001288250.1_48624001_1 - 5.3e-07 29.7 14.2 0.039 14.2 0.6 6.8 5 2 4 9 9 9 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001288250.1_48624001_1 - 0.0074 16.5 5.4 12 6.7 0.0 6.1 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.4 001288250.1_48624001_1 - 0.3 10.8 13.3 2.9 7.6 0.9 5.9 4 3 0 4 4 4 0 Leucine rich repeat Gp_dh_C PF02800.18 001288415.1_48623001_2 - 2.6e-71 238.2 0.0 3.5e-71 237.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 001288415.1_48623001_2 - 3.5e-34 117.1 0.0 7.7e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.18 001288415.1_48623001_2 - 0.00043 20.3 0.1 0.0014 18.6 0.0 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.17 001288415.1_48623001_2 - 0.045 13.0 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TAXi_C PF14541.4 001318633.1_48623001_1 - 7.8e-48 162.1 0.0 1.6e-47 161.1 0.0 1.5 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.4 001318633.1_48623001_1 - 2.2e-32 112.6 2.0 2.2e-32 112.6 2.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Glyco_transf_5 PF08323.9 001111531.3_53725001_3 - 7.3e-73 245.1 0.0 1.6e-72 244.0 0.0 1.5 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.18 001111531.3_53725001_3 - 4.4e-16 58.8 0.0 7.6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001111531.3_53725001_3 - 3.2e-12 46.9 0.3 5.9e-12 46.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001111531.3_53725001_3 - 0.00026 20.9 0.0 0.032 14.1 0.0 2.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 zf-RanBP PF00641.16 001318599.1_48623001_2 - 5e-16 57.6 30.4 3.2e-07 29.4 3.4 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.5 001318599.1_48623001_2 - 0.41 10.6 25.5 0.14 12.1 12.0 3.1 3 1 1 4 4 4 0 Double zinc ribbon ComX PF05952.10 001318599.1_48623001_3 - 0.0048 16.9 0.6 0.22 11.6 0.1 2.9 3 0 0 3 3 3 1 Bacillus competence pheromone ComX tify PF06200.12 001318575.1_48623001_2 - 1.5e-17 62.5 0.1 2.5e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 tify domain CCT_2 PF09425.8 001318575.1_48623001_2 - 1.2e-12 47.3 2.0 2.3e-12 46.4 2.0 1.4 1 0 0 1 1 1 1 Divergent CCT motif CCT PF06203.12 001318575.1_48623001_2 - 0.07 13.1 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 CCT motif Epimerase PF01370.19 001288059.1_48624001_3 - 1.8e-27 96.2 0.0 2.8e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001288059.1_48624001_3 - 8.4e-18 64.2 0.0 1.2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.3 001288059.1_48624001_3 - 1.8e-16 60.3 0.0 3.8e-16 59.2 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 001288059.1_48624001_3 - 2.1e-15 57.0 0.0 3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001288059.1_48624001_3 - 1.3e-12 47.3 0.0 1.1e-11 44.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.11 001288059.1_48624001_3 - 1.5e-09 37.7 0.0 2.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.8 001288059.1_48624001_3 - 1.8e-06 27.8 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.23 001288059.1_48624001_3 - 5.1e-05 22.7 0.0 0.0002 20.7 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.13 001288059.1_48624001_3 - 0.0002 20.5 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001288059.1_48624001_3 - 0.13 11.2 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain LRR_4 PF12799.5 144527.1_53725120_1 - 6.8e-06 26.2 0.5 0.21 11.9 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 144527.1_53725120_1 - 6.9e-05 22.4 3.9 9.7e-05 21.9 0.1 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.4 144527.1_53725120_1 - 0.044 13.7 0.0 11 6.2 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.31 144527.1_53725120_1 - 5.5 7.7 11.8 1.7e+02 3.2 0.0 6.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.4 144527.1_53725120_2 - 4.3e-07 29.5 0.6 6.8e-07 28.8 0.6 1.3 1 0 0 1 1 1 1 Leucine rich repeat Cupin_1 PF00190.20 001137400.2_53722001_2 - 3.7e-29 101.1 0.1 5.2e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.9 001137400.2_53722001_2 - 2.6e-08 33.3 0.0 4.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain PCO_ADO PF07847.10 001137400.2_53722001_2 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 PCO_ADO LRR_8 PF13855.4 145320.1_53724120_1 - 5e-23 80.5 6.3 2.3e-06 27.1 0.1 4.6 2 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.5 145320.1_53724120_1 - 7e-23 80.1 4.3 1.9e-05 24.8 0.0 6.5 4 3 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 145320.1_53724120_1 - 1.6e-10 39.7 7.3 5 7.9 0.0 8.8 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.4 145320.1_53724120_1 - 5.6e-06 25.9 10.5 4.1 7.6 0.1 8.7 10 0 0 10 10 10 1 Leucine Rich repeat LRR_4 PF12799.5 145320.1_53724120_2 - 2.5e-18 65.7 7.6 1.7e-05 24.9 0.2 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 145320.1_53724120_2 - 1.4e-15 56.7 13.1 8e-06 25.4 5.9 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.4 145320.1_53724120_2 - 3.9e-09 35.7 15.6 0.12 12.4 0.4 6.2 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.31 145320.1_53724120_2 - 1e-07 31.2 12.5 0.067 13.5 0.0 6.6 7 0 0 7 7 7 2 Leucine Rich Repeat Arf PF00025.19 001288147.1_48622001_3 - 2e-64 216.1 0.0 2.5e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.18 001288147.1_48622001_3 - 4.7e-09 35.7 0.1 2.3e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.11 001288147.1_48622001_3 - 6.7e-08 32.7 0.0 1.4e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 001288147.1_48622001_3 - 3.2e-07 30.0 0.0 4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.8 001288147.1_48622001_3 - 1.3e-06 27.8 0.0 1.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001288147.1_48622001_3 - 1.4e-06 28.3 0.0 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001288147.1_48622001_3 - 0.00048 19.4 0.0 0.0006 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.7 001288147.1_48622001_3 - 0.0064 16.1 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation OTCace_N PF02729.19 001318647.1_48623001_1 - 1.4e-46 157.9 0.1 1.1e-45 155.0 0.0 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.22 001318647.1_48623001_1 - 8.6e-32 110.2 0.0 1.4e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Brucella_OMP2 PF05244.9 001318647.1_48623001_1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Brucella outer membrane protein 2 RCC_reductase PF06405.9 001318612.1_48623001_3 - 3.2e-110 367.1 0.1 3.9e-110 366.9 0.1 1.1 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) Fe_bilin_red PF05996.10 001318612.1_48623001_3 - 0.013 15.0 0.0 0.02 14.4 0.0 1.4 1 1 0 1 1 1 0 Ferredoxin-dependent bilin reductase zf-Dof PF02701.13 001318616.1_48623001_1 - 2.4e-32 110.7 10.1 5.4e-32 109.6 10.1 1.6 1 0 0 1 1 1 1 Dof domain, zinc finger Dehydrin PF00257.17 001289013.1_48622001_1 - 9.1e-26 91.3 35.4 2.3e-18 67.2 28.2 2.2 1 1 1 2 2 2 2 Dehydrin Dsh_C PF12316.6 001289013.1_48622001_1 - 0.36 11.1 7.6 0.54 10.5 7.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Ndc1_Nup PF09531.8 001289013.1_48622001_1 - 4.1 5.8 5.5 4.3 5.7 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AP2 PF00847.18 001315858.1_06922001_1 - 1.2e-12 47.7 0.3 1.2e-12 47.7 0.3 1.8 2 0 0 2 2 2 1 AP2 domain Lipoxygenase PF00305.17 001316125.1_06926001_1 - 1.7e-299 994.9 0.0 2e-299 994.7 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001316125.1_06926001_1 - 4e-05 24.0 0.0 8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain G6PD_C PF02781.14 001288143.1_48625001_1 - 4.9e-112 373.7 0.0 6.5e-112 373.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.20 001288143.1_48625001_1 - 5.9e-58 196.3 0.0 1.1e-57 195.4 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain mTERF PF02536.12 001154394.2_53725001_3 - 5e-23 81.4 0.1 1.5e-21 76.5 0.1 2.5 1 1 0 1 1 1 1 mTERF Zn-ribbon_8 PF09723.8 001328133.1_53723001_1 - 0.044 13.8 2.8 0.067 13.2 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-ISL3 PF14690.4 001328133.1_53723001_1 - 0.048 14.1 4.6 0.4 11.2 4.6 2.3 1 1 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PPR_2 PF13041.4 001137088.2_53724001_1 - 1.4e-61 204.3 0.1 5.2e-13 48.8 0.0 9.9 4 2 6 10 10 10 9 PPR repeat family PPR_1 PF12854.5 001137088.2_53724001_1 - 1e-57 191.3 8.0 1.3e-09 37.4 0.1 10.3 11 0 0 11 11 11 7 PPR repeat PPR PF01535.18 001137088.2_53724001_1 - 2.4e-52 171.5 3.2 7e-07 28.9 0.1 10.6 11 0 0 11 11 10 8 PPR repeat PPR_3 PF13812.4 001137088.2_53724001_1 - 5.1e-27 93.6 0.0 1.2e-08 34.8 0.0 6.4 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR_long PF17177.2 001137088.2_53724001_1 - 6.2e-21 74.6 0.4 2.2e-06 27.1 0.0 5.0 1 1 4 5 5 5 4 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001137088.2_53724001_1 - 1e-08 35.2 20.7 0.13 13.0 0.7 8.8 6 3 4 10 10 10 3 Tetratricopeptide repeat TPR_10 PF13374.4 001137088.2_53724001_1 - 2e-07 30.5 7.1 0.12 12.1 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.4 001137088.2_53724001_1 - 2.3e-07 31.1 11.6 0.018 15.4 0.1 6.5 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.4 001137088.2_53724001_1 - 2e-05 24.2 0.0 11 6.2 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.4 001137088.2_53724001_1 - 3.4e-05 24.3 13.4 0.49 11.0 0.1 5.8 6 1 1 7 7 5 1 Tetratricopeptide repeat DUF3368 PF11848.6 001137088.2_53724001_1 - 0.00057 19.5 0.4 0.4 10.4 0.0 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3368) BTAD PF03704.15 001137088.2_53724001_1 - 0.0012 19.1 15.2 0.12 12.7 1.5 5.5 4 1 0 5 5 5 1 Bacterial transcriptional activator domain TPR_12 PF13424.4 001137088.2_53724001_1 - 0.0023 18.1 11.0 5.8 7.2 0.0 6.6 9 1 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001137088.2_53724001_1 - 0.0033 17.5 2.1 11 6.2 0.0 4.2 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 T2SSF PF00482.21 001137088.2_53724001_1 - 0.012 15.5 0.3 0.057 13.2 0.0 2.3 3 0 0 3 3 2 0 Type II secretion system (T2SS), protein F ATP13 PF12921.5 001137088.2_53724001_1 - 0.014 15.1 0.0 4 7.2 0.0 3.4 2 1 1 3 3 3 0 Mitochondrial ATPase expression MRP-S27 PF10037.7 001137088.2_53724001_1 - 0.018 13.9 0.0 0.051 12.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_2 PF07719.15 001137088.2_53724001_1 - 0.02 14.9 5.5 44 4.4 0.1 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat ELYS PF13934.4 001137088.2_53724001_1 - 0.087 12.7 0.2 4.1 7.2 0.1 3.2 3 1 1 4 4 4 0 Nuclear pore complex assembly TPR_6 PF13174.4 001137088.2_53724001_1 - 0.094 13.3 9.9 27 5.5 0.2 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_4 PF07721.12 001137088.2_53724001_1 - 0.21 12.2 29.4 0.16 12.5 0.9 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_21 PF09976.7 001137088.2_53724001_1 - 1.3 8.7 3.9 8.2 6.0 3.7 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain FA_desaturase_2 PF03405.12 001157671.2_53723001_3 - 1.2e-140 467.8 0.0 1.5e-140 467.5 0.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase TAXi_N PF14543.4 001157206.2_53724001_2 - 2.9e-45 154.6 5.1 5.6e-45 153.6 5.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.4 001157206.2_53724001_2 - 2.9e-37 127.8 0.0 4.4e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.21 001157206.2_53724001_2 - 2.3e-20 73.1 0.1 5.7e-12 45.5 0.1 2.8 2 1 0 2 2 2 2 Eukaryotic aspartyl protease PGM_PMM_IV PF00408.18 001150641.2_53723001_1 - 0.16 12.1 0.1 0.16 12.1 0.1 1.8 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1674 PF07896.10 001328212.1_53722001_2 - 3.3e-16 59.4 4.2 3.3e-16 59.4 4.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) zf-CCHC PF00098.21 001347942.1_53723001_2 - 2e-35 119.1 36.7 3.2e-09 36.3 3.3 4.6 4 0 0 4 4 4 4 Zinc knuckle CSD PF00313.20 001347942.1_53723001_2 - 1.3e-27 95.3 0.3 1.8e-27 94.9 0.3 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC_3 PF13917.4 001347942.1_53723001_2 - 5.1e-09 35.8 9.7 0.06 13.2 0.1 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_5 PF14787.4 001347942.1_53723001_2 - 1.8e-06 27.4 24.0 0.049 13.2 1.2 4.3 4 0 0 4 4 4 4 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.4 001347942.1_53723001_2 - 2e-05 24.1 22.9 0.062 12.9 0.5 4.4 4 0 0 4 4 4 4 Zinc knuckle OB_RNB PF08206.9 001347942.1_53723001_2 - 0.00013 21.4 0.1 0.00025 20.6 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain zf-CCHC_2 PF13696.4 001347942.1_53723001_2 - 0.25 11.1 25.6 2 8.2 1.0 4.5 4 0 0 4 4 4 0 Zinc knuckle FA_hydroxylase PF04116.11 001321521.1_53723001_1 - 1.1e-23 83.9 13.7 2.1e-23 83.0 13.7 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Cation_ATPase_C PF00689.19 001321521.1_53723001_1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF4666 PF15697.3 001150375.2_53722001_1 - 2.3e-37 127.9 2.3 4.5e-37 127.0 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4666) UDPGT PF00201.16 001137423.2_53724001_2 - 9.3e-21 74.0 0.0 1.4e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_hydro_17 PF00332.16 001318566.1_48623001_1 - 2.4e-92 309.5 0.1 2.8e-92 309.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Sporozoite_P67 PF05642.9 001318566.1_48623001_1 - 0.041 11.9 0.4 0.048 11.6 0.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Phosphorylase PF00343.18 001288286.1_48629001_1 - 2.2e-300 998.0 0.0 1.7e-168 562.0 0.0 2.0 2 0 0 2 2 2 2 Carbohydrate phosphorylase Glyco_hydro_17 PF00332.16 001288684.1_48623001_1 - 6e-117 390.4 0.2 6.7e-117 390.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001288504.1_48623001_1 - 5.9e-23 81.2 0.1 1e-22 80.4 0.1 1.4 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.16 001288504.1_48623001_1 - 5.4e-13 48.9 0.1 8e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_17 PF00332.16 001288182.1_48623001_1 - 1.5e-97 326.6 0.2 1.8e-97 326.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001288182.1_48623001_1 - 3.6e-23 81.9 2.1 6.8e-23 81.0 2.1 1.5 1 0 0 1 1 1 1 X8 domain NPH-II PF12011.6 001288182.1_48623001_1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NPH-II Glyco_hydro_17 PF00332.16 001318636.1_48623001_1 - 2.1e-93 313.0 0.6 2.5e-93 312.8 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001318636.1_48623001_1 - 1.6e-21 76.6 1.4 3.2e-21 75.6 1.4 1.5 1 0 0 1 1 1 1 X8 domain ABC2_membrane_3 PF12698.5 001318636.1_48623001_1 - 0.016 14.2 3.8 0.031 13.3 3.8 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF1948 PF09185.8 001318636.1_48623001_1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) adh_short_C2 PF13561.4 001288255.1_48623001_1 - 8.8e-61 205.3 0.6 1.1e-60 204.9 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001288255.1_48623001_1 - 5.2e-50 169.5 0.3 6.9e-50 169.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001288255.1_48623001_1 - 1.7e-08 34.5 0.2 3.1e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001288255.1_48623001_1 - 0.00051 19.4 0.4 0.038 13.3 0.1 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001288255.1_48623001_1 - 0.0018 17.2 0.6 0.0026 16.7 0.6 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_17 PF00332.16 001288187.1_48623001_1 - 7.7e-92 307.9 0.3 8.8e-92 307.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001288560.1_48623001_1 - 6.4e-22 77.9 3.3 9.9e-22 77.3 3.3 1.3 1 0 0 1 1 1 1 X8 domain Glyco_transf_29 PF00777.16 001288066.1_48624001_3 - 4.4e-27 95.0 0.0 6.7e-21 74.7 0.0 2.4 1 1 1 2 2 2 2 Glycosyltransferase family 29 (sialyltransferase) Glyco_hydro_17 PF00332.16 001318642.1_48623001_1 - 5.5e-69 232.8 0.1 8.5e-69 232.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001318642.1_48623001_1 - 3.1e-18 66.1 7.5 6.6e-18 65.0 7.5 1.6 1 0 0 1 1 1 1 X8 domain GTP_cyclohydro2 PF00925.18 001318642.1_48623001_1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II Pkinase PF00069.23 001288024.1_48624001_2 - 3.3e-75 252.7 0.0 5e-75 252.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001288024.1_48624001_2 - 4e-39 134.3 0.0 5.5e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.17 001288024.1_48624001_2 - 1e-13 50.7 0.2 2.4e-13 49.5 0.2 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.4 001288024.1_48624001_2 - 1.9e-07 30.6 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like AdenylateSensor PF16579.3 001288024.1_48624001_2 - 1.1e-06 29.0 0.6 0.0018 18.6 0.0 2.7 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase UBA PF00627.29 001288024.1_48624001_2 - 0.00039 20.1 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.20 001288024.1_48624001_2 - 0.0012 18.4 0.5 0.0024 17.4 0.5 1.5 1 0 0 1 1 1 1 RIO1 family UBA_3 PF09288.8 001288024.1_48624001_2 - 0.037 13.7 3.3 0.047 13.4 0.1 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Complex1_51K PF01512.15 001288191.1_48624001_2 - 1.2e-47 161.4 0.0 2.1e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.7 001288191.1_48624001_2 - 3.6e-29 100.5 0.0 6.5e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.7 001288191.1_48624001_2 - 1.6e-07 31.0 0.0 3.6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain X8 PF07983.11 001288336.1_48622001_1 - 2.7e-21 75.9 3.0 4.7e-21 75.1 3.0 1.4 1 0 0 1 1 1 1 X8 domain Mito_carr PF00153.25 001288217.1_48623001_1 - 1.4e-61 204.3 0.3 4e-19 68.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.20 001315950.1_06924001_3 - 2.1e-111 372.8 0.0 2.5e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_assoc_C PF09821.7 001315950.1_06924001_3 - 0.044 14.2 0.1 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 C-terminal AAA-associated domain Glyco_hydro_17 PF00332.16 001287881.1_48623001_1 - 5.1e-89 298.6 0.1 5.8e-89 298.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001318659.1_48622001_1 - 3.4e-21 75.6 7.3 5.8e-21 74.8 7.3 1.4 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.16 001288245.1_48623001_1 - 1.1e-75 254.8 0.0 1.4e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001288245.1_48623001_1 - 7.3e-21 74.5 1.6 1.7e-20 73.3 1.6 1.7 1 0 0 1 1 1 1 X8 domain OPA3 PF07047.10 001288245.1_48623001_2 - 0.0033 17.1 0.2 0.0053 16.4 0.2 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) potato_inhibit PF00280.16 001288272.1_48621001_1 - 4.4e-23 81.6 0.2 5.7e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Glyco_hydro_17 PF00332.16 001318593.1_48623001_1 - 1.2e-72 244.8 0.1 1.5e-72 244.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001318593.1_48623001_1 - 2.5e-17 63.2 4.0 3.2e-17 62.9 3.1 1.7 2 0 0 2 2 2 1 X8 domain X8 PF07983.11 001288081.1_48622001_1 - 2.2e-20 73.0 0.9 3.5e-20 72.3 0.9 1.3 1 0 0 1 1 1 1 X8 domain Terpene_synth_C PF03936.14 001288242.1_48624001_2 - 2.4e-101 338.5 6.6 4.6e-101 337.6 6.6 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001288242.1_48624001_2 - 1.1e-57 194.6 1.4 2.1e-57 193.7 1.4 1.5 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain AP2 PF00847.18 001288674.1_48622001_1 - 2.7e-14 53.0 2.0 4.5e-14 52.3 2.0 1.4 1 0 0 1 1 1 1 AP2 domain Glyco_hydro_19 PF00182.17 001318607.1_48622001_1 - 9.5e-134 444.4 3.0 1.1e-133 444.2 3.0 1.0 1 0 0 1 1 1 1 Chitinase class I SRF-TF PF00319.16 001288397.1_48622001_2 - 5.6e-25 86.4 0.2 1.1e-24 85.5 0.2 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001288397.1_48622001_2 - 6.4e-20 71.0 9.9 6.4e-20 71.0 9.9 1.9 2 1 0 2 2 2 1 K-box region L31 PF09784.7 001288397.1_48622001_2 - 0.0078 16.5 1.8 0.018 15.3 1.8 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Herpes_BLRF2 PF05812.10 001288397.1_48622001_2 - 1.5 8.8 7.7 0.24 11.4 3.8 1.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Vpu PF00558.17 001288397.1_48622001_2 - 4.3 7.0 7.5 1.1 9.0 3.1 2.1 1 1 1 2 2 2 0 Vpu protein Glyco_hydro_17 PF00332.16 001288281.1_48623001_1 - 5.6e-88 295.2 0.0 7.3e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001288281.1_48623001_1 - 2.5e-19 69.6 0.0 4.8e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 X8 domain SecG PF03840.12 001288281.1_48623001_1 - 0.076 13.0 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Glyco_hydro_17 PF00332.16 001318700.1_48623001_1 - 1.3e-115 386.0 0.1 1.5e-115 385.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_17 PF00332.16 001288359.1_48623001_1 - 6.2e-86 288.5 1.7 7.9e-86 288.1 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001288359.1_48623001_1 - 2.2e-18 66.6 0.4 4.4e-18 65.6 0.4 1.5 1 0 0 1 1 1 1 X8 domain Xol-1_N PF09108.8 001288359.1_48623001_1 - 0.034 13.9 0.3 0.077 12.7 0.2 1.5 1 1 0 1 1 1 0 Switch protein XOL-1, N-terminal Glyco_hydro_17 PF00332.16 001318581.1_48623001_1 - 3.1e-100 335.4 2.2 4e-100 335.1 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001318581.1_48623001_1 - 5.7e-23 81.3 3.4 1e-22 80.4 3.4 1.4 1 0 0 1 1 1 1 X8 domain X8 PF07983.11 001287991.1_48622001_1 - 1.9e-19 70.0 4.4 2.7e-19 69.5 4.4 1.3 1 0 0 1 1 1 1 X8 domain ABC_membrane PF00664.21 001288390.1_48629001_3 - 9e-114 379.6 30.8 2.9e-57 194.3 13.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001288390.1_48629001_3 - 1.2e-72 242.7 0.0 5.7e-35 120.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.17 001288390.1_48629001_3 - 4.5e-16 58.8 1.2 2.1e-05 23.9 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.4 001288390.1_48629001_3 - 1.1e-08 35.5 3.6 0.005 17.1 0.7 3.3 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.10 001288390.1_48629001_3 - 2.4e-07 30.1 0.1 0.031 13.4 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.4 001288390.1_48629001_3 - 8e-07 29.3 0.5 0.031 14.4 0.0 3.2 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.7 001288390.1_48629001_3 - 2.5e-06 26.4 0.5 0.052 12.2 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.14 001288390.1_48629001_3 - 2.8e-06 27.2 1.4 0.11 12.3 0.0 3.4 4 0 0 4 4 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.4 001288390.1_48629001_3 - 2.9e-06 26.8 0.2 0.035 13.7 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.4 001288390.1_48629001_3 - 6.2e-06 25.9 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.4 001288390.1_48629001_3 - 2.4e-05 24.0 0.2 0.25 10.9 0.0 3.3 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.18 001288390.1_48629001_3 - 7.6e-05 21.9 0.0 0.091 11.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.12 001288390.1_48629001_3 - 0.00011 22.1 0.1 0.8 9.6 0.0 3.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) APS_kinase PF01583.18 001288390.1_48629001_3 - 0.00026 20.8 0.4 0.2 11.4 0.1 2.7 3 0 0 3 3 2 2 Adenylylsulphate kinase DUF87 PF01935.15 001288390.1_48629001_3 - 0.00037 20.5 0.2 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.4 001288390.1_48629001_3 - 0.0004 19.9 0.0 0.25 10.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.27 001288390.1_48629001_3 - 0.00041 20.6 1.1 3.2 8.1 0.0 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.11 001288390.1_48629001_3 - 0.001 18.1 0.3 0.38 9.7 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) PRK PF00485.16 001288390.1_48629001_3 - 0.0014 18.3 0.1 1.3 8.6 0.0 2.7 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.4 001288390.1_48629001_3 - 0.0028 17.4 3.6 1.3 8.6 0.0 3.8 4 1 0 5 5 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.4 001288390.1_48629001_3 - 0.0074 16.4 8.7 0.67 10.1 0.3 4.2 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.19 001288390.1_48629001_3 - 0.0088 15.3 0.0 3.6 6.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.4 001288390.1_48629001_3 - 0.0088 15.7 0.1 2.1 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.4 001288390.1_48629001_3 - 0.027 14.9 0.0 9.4 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.4 001288390.1_48629001_3 - 0.032 14.2 0.0 5.4 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.20 001288390.1_48629001_3 - 0.06 13.6 0.0 11 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.4 001288390.1_48629001_3 - 0.071 13.2 0.4 21 5.2 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.4 001288390.1_48629001_3 - 0.092 13.1 0.1 24 5.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.21 001288390.1_48629001_3 - 0.18 11.8 2.3 22 5.1 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase KNOX2 PF03791.11 001288425.1_48623001_3 - 8.2e-25 86.1 0.2 1.7e-24 85.1 0.2 1.6 1 0 0 1 1 1 1 KNOX2 domain KNOX1 PF03790.11 001288425.1_48623001_3 - 1.2e-20 72.9 0.1 1.9e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 KNOX1 domain Homeobox_KN PF05920.9 001288425.1_48623001_3 - 1.7e-17 62.9 3.2 4.5e-17 61.5 3.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain ELK PF03789.11 001288425.1_48623001_3 - 1e-07 31.7 4.2 2e-07 30.7 4.2 1.5 1 0 0 1 1 1 1 ELK domain Homeobox PF00046.27 001288425.1_48623001_3 - 2.1e-06 27.3 0.9 4.3e-06 26.3 0.9 1.6 1 0 0 1 1 1 1 Homeobox domain Serglycin PF04360.10 001288425.1_48623001_3 - 0.042 13.7 1.5 0.07 12.9 1.5 1.3 1 0 0 1 1 1 0 Serglycin DOG1 PF14144.4 001318544.1_48623001_2 - 3.8e-30 103.8 0.0 9.4e-30 102.5 0.0 1.7 1 0 0 1 1 1 1 Seed dormancy control bZIP_1 PF00170.19 001318544.1_48623001_2 - 1.8e-06 27.8 14.7 1.8e-06 27.8 14.7 2.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.13 001318544.1_48623001_2 - 4.8e-05 23.2 12.9 0.00013 21.8 12.9 1.7 1 0 0 1 1 1 1 Basic region leucine zipper WASH-7_N PF14745.4 001318544.1_48623001_2 - 0.05 11.9 0.0 0.076 11.3 0.0 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal bZIP_Maf PF03131.15 001318544.1_48623001_2 - 0.94 9.9 12.5 0.11 12.9 7.3 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Glyco_hydro_17 PF00332.16 001318630.1_48623001_1 - 3.7e-70 236.7 0.0 5.2e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001318630.1_48623001_1 - 6.9e-18 65.0 1.4 1.4e-17 64.0 1.4 1.5 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.16 001288434.1_48623001_1 - 8.4e-100 334.0 0.6 1.1e-99 333.7 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001288434.1_48623001_1 - 2.3e-20 72.9 2.4 4.4e-20 72.0 2.4 1.5 1 0 0 1 1 1 1 X8 domain Peptidase_M57 PF12388.6 001288434.1_48623001_1 - 0.022 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Thioredoxin PF00085.18 001318563.1_48623001_1 - 2.2e-19 69.2 0.2 1.9e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_9 PF14595.4 001318563.1_48623001_1 - 8.4e-05 22.2 0.5 0.0084 15.8 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_7 PF13899.4 001318563.1_48623001_1 - 0.00017 21.5 0.3 0.0057 16.7 0.1 2.6 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.4 001318563.1_48623001_1 - 0.00018 21.7 0.3 0.045 14.0 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like DIM1 PF02966.14 001318563.1_48623001_1 - 0.00018 21.1 1.2 0.3 10.7 0.3 2.3 2 0 0 2 2 2 2 Mitosis protein DIM1 Thioredoxin_2 PF13098.4 001318563.1_48623001_1 - 0.013 15.8 0.4 1.6 9.1 0.1 2.8 2 2 0 2 2 2 0 Thioredoxin-like domain HyaE PF07449.9 001318563.1_48623001_1 - 0.027 14.3 0.0 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.8 001318563.1_48623001_1 - 0.066 12.8 1.0 0.25 10.9 0.1 2.1 2 1 1 3 3 3 0 Redoxin Glyco_hydro_17 PF00332.16 001288672.1_48623001_1 - 2.7e-91 306.1 0.1 3.2e-91 305.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_17 PF00332.16 001318626.1_48623001_1 - 1.7e-72 244.4 0.0 2e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001318626.1_48623001_1 - 2.4e-17 63.3 1.2 4e-17 62.5 1.2 1.4 1 0 0 1 1 1 1 X8 domain APG6 PF04111.10 001288562.1_48624001_1 - 2.5e-106 355.5 8.0 3.1e-106 355.1 8.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Ribosomal_L22e PF01776.15 001288562.1_48624001_1 - 0.03 14.6 0.4 0.091 13.0 0.4 1.8 1 0 0 1 1 1 0 Ribosomal L22e protein family ERM PF00769.17 001288562.1_48624001_1 - 0.041 13.6 11.8 0.07 12.8 11.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family zf-AD PF07776.13 001288562.1_48624001_1 - 0.051 13.7 0.5 1.3 9.2 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) TBPIP PF07106.11 001288562.1_48624001_1 - 0.089 12.4 6.6 0.17 11.5 6.6 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) eIF3_N PF09440.8 001288562.1_48624001_1 - 0.17 12.1 3.1 0.73 10.1 0.0 2.4 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain IncA PF04156.12 001288562.1_48624001_1 - 0.86 9.2 12.8 1.3 8.6 12.8 1.2 1 0 0 1 1 1 0 IncA protein Spc24 PF08286.9 001288562.1_48624001_1 - 0.99 9.5 9.3 1.3 9.2 6.2 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 RRM_1 PF00076.20 001287862.1_48622001_3 - 1.9e-23 82.0 0.0 1.9e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001287862.1_48622001_3 - 5.5e-15 55.0 0.0 1.6e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.4 001287862.1_48622001_3 - 4.3e-05 23.3 0.0 6.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) X8 PF07983.11 001288000.1_48622001_1 - 1.4e-21 76.8 7.5 2.3e-21 76.1 7.5 1.3 1 0 0 1 1 1 1 X8 domain Stress-antifung PF01657.15 001334110.1_03723001_1 - 2.4e-30 104.9 11.6 1.2e-18 67.3 5.0 2.2 2 0 0 2 2 2 2 Salt stress response/antifungal TPR_19 PF14559.4 001332744.1_03724001_3 - 2.4e-05 24.6 0.3 0.0014 19.0 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.15 001332744.1_03724001_3 - 4.7e-05 23.0 3.8 0.02 14.8 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.4 001332744.1_03724001_3 - 9.6e-05 22.8 0.3 0.3 11.9 0.1 4.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.4 001332744.1_03724001_3 - 0.0018 18.4 3.4 1.2 9.3 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.4 001332744.1_03724001_3 - 0.0084 16.1 0.0 0.11 12.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.26 001332744.1_03724001_3 - 0.0095 15.6 0.1 1 9.2 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF309 PF03745.12 001332744.1_03724001_3 - 0.02 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF309) ANAPC3 PF12895.5 001332744.1_03724001_3 - 0.13 12.4 3.6 24 5.1 0.1 3.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 FH2 PF02181.21 001332639.1_03726001_1 - 3.1e-66 223.9 0.0 6.2e-66 222.9 0.0 1.4 2 0 0 2 2 2 1 Formin Homology 2 Domain FH2 PF02181.21 001332639.1_03726001_3 - 6.4e-39 134.0 1.7 8.7e-39 133.6 1.7 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Telomere_Sde2 PF13019.4 001332639.1_03726001_3 - 0.058 13.1 4.8 0.75 9.5 4.8 2.1 1 1 0 1 1 1 0 Telomere stability and silencing zf-4CXXC_R1 PF10497.7 001334286.1_03724001_3 - 3.6e-34 116.8 7.8 3.6e-34 116.8 7.8 2.1 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WHIM1 PF15612.4 001334286.1_03724001_3 - 4.5e-05 22.8 0.1 0.0001 21.6 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Kelch_5 PF13854.4 100001.2_03724001_1 - 0.0079 16.0 0.3 0.015 15.1 0.3 1.4 1 0 0 1 1 1 1 Kelch motif p450 PF00067.20 100001.2_03724001_2 - 1.4e-74 251.4 0.0 1.9e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PPR PF01535.18 100095.4_03724001_2 - 2.8e-26 89.8 15.8 7.5e-05 22.6 0.0 8.3 8 0 0 8 8 8 6 PPR repeat PPR_2 PF13041.4 100095.4_03724001_2 - 6.1e-23 80.6 13.1 3.3e-06 27.1 0.0 6.6 5 1 1 6 6 6 5 PPR repeat family PPR_3 PF13812.4 100095.4_03724001_2 - 3.4e-13 49.3 0.1 5.3e-05 23.1 0.0 5.5 5 1 2 7 7 7 2 Pentatricopeptide repeat domain PPR_long PF17177.2 100095.4_03724001_2 - 5e-08 32.4 0.3 9.2e-05 21.8 0.0 3.7 1 1 1 3 3 3 1 Pentacotripeptide-repeat region of PROPR TPR_19 PF14559.4 100095.4_03724001_2 - 6.2e-07 29.7 0.0 0.9 10.0 0.0 4.4 4 1 0 4 4 3 2 Tetratricopeptide repeat PPR_1 PF12854.5 100095.4_03724001_2 - 8.9e-06 25.2 0.1 2.5 7.8 0.0 5.2 5 0 0 5 5 5 1 PPR repeat TPR_14 PF13428.4 100095.4_03724001_2 - 3.1e-05 24.3 0.0 3 8.8 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.4 100095.4_03724001_2 - 0.0029 17.4 0.0 4.9 7.3 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.15 100095.4_03724001_2 - 0.009 15.9 0.1 9.3 6.5 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.4 100095.4_03724001_2 - 0.013 15.7 0.0 2.3 8.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.26 100095.4_03724001_2 - 0.021 14.5 0.1 0.83 9.4 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2095 PF09868.7 100095.4_03724001_2 - 0.084 12.7 0.0 0.39 10.5 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2095) TPR_8 PF13181.4 100095.4_03724001_2 - 0.16 12.1 10.5 3.7 7.9 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat SNF2_N PF00176.21 001331355.1_03725001_1 - 1.6e-46 158.6 0.0 1.2e-45 155.6 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.29 001331355.1_03725001_1 - 9.6e-14 51.6 0.0 2.3e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001331355.1_03725001_1 - 3.7e-09 36.7 0.0 6.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.3 001331355.1_03725001_1 - 0.0065 15.6 0.0 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase TFIID-18kDa PF02269.14 100148.3_03722001_1 - 4.8e-30 103.3 0.2 7.1e-30 102.7 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Glyco_hydro_28 PF00295.15 100158.3_03724001_1 - 5.7e-90 301.5 12.8 9.7e-90 300.8 12.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.5 100158.3_03724001_1 - 2.4e-09 37.3 3.9 2.4e-09 37.3 3.9 2.1 1 1 1 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.4 100158.3_03724001_1 - 0.017 14.9 11.6 0.05 13.3 11.5 1.8 1 1 0 1 1 1 0 Right handed beta helix region NosD PF05048.11 100158.3_03724001_1 - 3.3 6.8 10.3 0.85 8.7 5.8 2.0 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Ribosomal_L22e PF01776.15 100164.2_03721001_1 - 9.2e-42 141.7 2.6 1.2e-41 141.4 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family T4_Gp59_N PF08993.8 100164.2_03721001_1 - 0.0098 16.1 0.6 0.014 15.7 0.6 1.2 1 0 0 1 1 1 1 T4 gene Gp59 loader of gp41 DNA helicase DUF4011 PF13195.4 100211.4_03729001_3 - 1.5 8.6 9.9 0.43 10.4 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) PPR_2 PF13041.4 100238.4_03725001_2 - 1.3e-98 322.9 29.0 1.2e-16 60.5 0.0 12.7 3 1 11 14 14 14 11 PPR repeat family PPR_1 PF12854.5 100238.4_03725001_2 - 5.1e-96 313.9 20.0 1.3e-12 47.0 0.0 13.9 14 0 0 14 14 14 10 PPR repeat PPR PF01535.18 100238.4_03725001_2 - 3.7e-84 271.2 36.1 2e-09 36.9 0.1 13.9 14 0 0 14 14 14 12 PPR repeat PPR_3 PF13812.4 100238.4_03725001_2 - 2.3e-42 142.7 10.5 4.3e-09 36.2 0.0 8.9 6 3 3 10 10 9 7 Pentatricopeptide repeat domain PPR_long PF17177.2 100238.4_03725001_2 - 2.6e-25 88.9 0.0 2e-11 43.6 0.0 3.5 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PROPR RPM2 PF08579.9 100238.4_03725001_2 - 6.8e-07 29.5 0.0 0.00086 19.5 0.0 3.9 2 1 2 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.4 100238.4_03725001_2 - 2.2e-06 27.9 0.0 18 6.4 0.0 6.4 6 2 2 8 8 5 0 Tetratricopeptide repeat MRP-S27 PF10037.7 100238.4_03725001_2 - 0.00016 20.5 0.1 0.011 14.5 0.0 3.1 3 2 0 3 3 3 1 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.4 100238.4_03725001_2 - 0.00026 21.3 0.0 3.4 8.1 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Clathrin PF00637.18 100238.4_03725001_2 - 0.0035 17.1 0.0 4.6 7.0 0.0 3.5 2 1 1 3 3 3 1 Region in Clathrin and VPS ECSIT PF06239.9 100238.4_03725001_2 - 0.0047 15.9 0.2 0.96 8.4 0.0 3.3 3 1 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_10 PF13374.4 100238.4_03725001_2 - 0.0051 16.5 0.2 18 5.3 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RabGAP-TBC PF00566.16 100238.4_03725001_2 - 0.011 15.2 0.0 0.84 9.1 0.0 2.8 3 1 0 3 3 3 0 Rab-GTPase-TBC domain TPR_12 PF13424.4 100238.4_03725001_2 - 0.015 15.5 0.0 40 4.5 0.0 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.4 100238.4_03725001_2 - 0.078 13.6 0.0 2.9 8.6 0.0 3.0 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.26 100238.4_03725001_2 - 0.16 11.7 1.5 52 3.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.15 100238.4_03725001_2 - 0.65 10.1 8.8 27 5.1 0.0 6.1 8 0 0 8 8 7 0 Tetratricopeptide repeat ELMO_CED12 PF04727.11 001331430.1_03723001_1 - 2.4e-47 161.2 0.1 3.7e-47 160.6 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family FMO-like PF00743.17 100340.4_03724001_3 - 2.5e-26 92.1 0.0 3.8e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.4 100340.4_03724001_3 - 7.7e-25 87.6 0.0 7.3e-23 81.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 100340.4_03724001_3 - 9.4e-16 57.7 0.0 1.3e-12 47.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.12 100340.4_03724001_3 - 1.2e-12 47.6 0.0 1.5e-09 37.4 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 100340.4_03724001_3 - 3.6e-06 27.3 0.1 0.094 13.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.17 100340.4_03724001_3 - 1.3e-05 24.6 0.1 0.0021 17.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.4 100340.4_03724001_3 - 9.1e-05 22.4 0.0 0.15 11.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.4 100340.4_03724001_3 - 9.8e-05 22.4 0.0 0.00029 20.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.14 100340.4_03724001_3 - 0.011 15.2 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DAO PF01266.22 100340.4_03724001_3 - 0.014 14.9 0.1 0.45 10.0 0.1 2.9 4 0 0 4 4 4 0 FAD dependent oxidoreductase Thi4 PF01946.15 100340.4_03724001_3 - 0.014 14.5 0.5 0.092 11.8 0.1 2.1 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.22 100340.4_03724001_3 - 0.043 12.8 0.9 0.31 9.9 0.4 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.20 100340.4_03724001_3 - 0.048 12.6 0.0 8 5.3 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.10 100340.4_03724001_3 - 0.074 12.0 0.3 1.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.18 100340.4_03724001_3 - 0.097 12.6 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.12 100340.4_03724001_3 - 0.13 10.8 1.5 0.42 9.1 0.3 2.3 3 0 0 3 3 3 0 HI0933-like protein ThiF PF00899.19 001035893.1_03724001_2 - 1.8e-13 50.3 0.1 2.6e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 ThiF family ANF_receptor PF01094.26 001331527.1_03726001_3 - 3.2e-81 273.0 0.3 5.2e-81 272.3 0.3 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001331527.1_03726001_3 - 2.7e-29 101.8 0.5 4.7e-29 101.0 0.5 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Peripla_BP_6 PF13458.4 001331527.1_03726001_3 - 1e-22 81.2 0.0 1.4e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein SBP_bac_3 PF00497.18 001331527.1_03726001_3 - 1.1e-11 44.5 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.7 001331527.1_03726001_3 - 9.1e-11 41.8 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site START PF01852.17 179265.2_03726001_3 - 9.9e-64 214.4 0.1 3.8e-63 212.5 0.1 1.9 3 0 0 3 3 3 1 START domain Homeobox PF00046.27 179265.2_03726001_3 - 5.9e-17 61.1 5.4 1.3e-16 60.0 5.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 179265.2_03726001_3 - 0.0011 18.7 0.3 0.0027 17.4 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-Mss51 PF13824.4 179265.2_03726001_3 - 0.39 10.8 3.5 1.2 9.1 3.5 1.9 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SNARE_assoc PF09335.9 001331545.1_03724001_3 - 1.5e-06 28.5 0.1 1.5e-06 28.5 0.1 3.3 4 0 0 4 4 4 1 SNARE associated Golgi protein PSII_Pbs27 PF13326.4 100418.3_03722001_2 - 3.2e-51 173.2 0.2 4.1e-51 172.9 0.2 1.1 1 0 0 1 1 1 1 Photosystem II Pbs27 FA_desaturase PF00487.22 100516.4_03723001_2 - 4e-15 56.2 20.0 4e-15 56.2 20.0 1.9 1 1 1 2 2 2 1 Fatty acid desaturase DUF2324 PF10086.7 100516.4_03723001_2 - 0.031 13.5 0.7 0.053 12.7 0.7 1.3 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) PHF5 PF03660.12 001331683.1_03722001_1 - 9.1e-50 167.1 14.3 1.5e-49 166.4 14.3 1.4 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.11 001331683.1_03722001_1 - 0.46 8.2 8.4 0.59 7.8 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 TPR_17 PF13431.4 001035907.1_03725001_2 - 4.2e-11 42.3 6.2 0.003 17.7 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.4 001035907.1_03725001_2 - 6.8e-05 23.2 3.5 0.016 15.8 2.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.4 001035907.1_03725001_2 - 0.00011 22.6 2.7 0.00021 21.8 2.7 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.4 001035907.1_03725001_2 - 0.0003 21.1 5.1 0.00048 20.4 1.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.26 001035907.1_03725001_2 - 0.0025 17.4 0.7 0.56 10.0 0.9 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.4 001035907.1_03725001_2 - 0.0068 16.4 2.5 0.65 10.2 0.7 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.15 001035907.1_03725001_2 - 0.031 14.2 3.9 0.25 11.4 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.4 001035907.1_03725001_2 - 0.48 10.5 1.7 14 5.8 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.5 100645.2_03724001_2 - 2.5e-44 149.6 10.4 8.5e-13 48.6 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.4 100645.2_03724001_2 - 6e-38 128.6 0.2 2.2e-10 40.7 0.0 6.8 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.4 100645.2_03724001_2 - 9.9e-38 127.5 3.3 1.9e-10 40.7 0.1 7.5 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.4 100645.2_03724001_2 - 2.7e-35 116.2 0.2 0.00016 21.7 0.0 8.9 9 0 0 9 9 8 7 Ankyrin repeat Ank PF00023.28 100645.2_03724001_2 - 2.1e-32 110.0 4.1 2.2e-05 24.5 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat PGG PF13962.4 100645.2_03724001_2 - 4.3e-27 94.1 8.2 8.1e-27 93.2 8.2 1.5 1 0 0 1 1 1 1 Domain of unknown function CorA PF01544.16 100645.2_03724001_2 - 0.0057 15.9 0.8 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SLAC1 PF03595.15 100645.2_03724001_2 - 0.0076 15.5 10.2 0.011 14.9 10.2 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2871 PF11070.6 100645.2_03724001_2 - 0.39 10.9 6.7 0.23 11.6 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) DUF1843 PF08898.8 100645.2_03724001_2 - 0.73 10.2 3.6 5 7.6 0.5 3.3 3 0 0 3 3 2 0 Domain of unknown function (DUF1843) SUR7 PF06687.10 100645.2_03724001_2 - 0.78 9.2 9.7 1.6 8.2 9.0 1.8 1 1 1 2 2 2 0 SUR7/PalI family Srg PF02118.19 100645.2_03724001_2 - 2.3 7.7 13.6 0.81 9.2 10.4 1.7 1 1 0 1 1 1 0 Srg family chemoreceptor UPF0233 PF06781.10 100645.2_03724001_2 - 2.9 7.9 8.9 52 3.9 7.9 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) MFS_1 PF07690.14 100685.1_03724001_1 - 9.7e-21 73.9 41.9 1.4e-20 73.5 41.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CHB_HEX_C_1 PF13290.4 100685.1_03724001_1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain ABC2_membrane_2 PF12679.5 100685.1_03724001_1 - 2.4 7.2 11.3 4.7 6.3 1.1 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Sugar_tr PF00083.22 001084027.2_03724001_1 - 1.9e-91 307.1 25.8 2.4e-91 306.7 25.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001084027.2_03724001_1 - 9.1e-21 74.0 38.7 1e-20 73.8 31.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily THUMP PF02926.15 100799.3_03723001_3 - 0.00011 22.2 0.0 0.001 19.1 0.1 2.3 2 0 0 2 2 2 1 THUMP domain Ribosomal_L21e PF01157.16 100831.4_03722001_3 - 1.2e-43 146.8 4.0 1.8e-43 146.2 4.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e SepSecS PF05889.11 100831.4_03722001_3 - 0.09 11.3 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS His_Phos_1 PF00300.20 148453.3_03722001_1 - 8.5e-16 58.1 0.2 4.6e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pardaxin PF07425.9 148453.3_03722001_1 - 0.16 11.5 0.0 0.43 10.1 0.0 1.7 1 0 0 1 1 1 0 Pardaxin Pribosyltran PF00156.25 001331922.1_03724001_1 - 1.4e-08 34.3 0.0 2.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.4 001331922.1_03724001_1 - 7.1e-07 29.3 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.4 001331922.1_03724001_3 - 5.6e-07 29.4 0.0 8.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pet191_N PF10203.7 001123793.1_03722001_2 - 1e-15 57.6 4.7 1.6e-15 57.0 4.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Alfin PF12165.6 101016.4_03723001_3 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Alfin PDT PF00800.16 001035947.1_03724001_1 - 2e-59 200.3 0.0 2.7e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.23 001035947.1_03724001_1 - 0.0034 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 ACT domain GCV_T PF01571.19 101057.5_03725001_1 - 1.1e-85 286.9 0.0 1.4e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.9 101057.5_03725001_1 - 1.7e-23 82.5 0.0 2.9e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain tRNA-synt_2b PF00587.23 179316.3_03725001_1 - 5.9e-27 94.7 0.0 1.8e-26 93.1 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.20 179316.3_03725001_1 - 3.8e-22 78.4 10.6 6e-22 77.8 10.6 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF3490 PF11995.6 179316.3_03725001_1 - 0.036 13.8 1.5 0.078 12.7 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) DUF342 PF03961.11 179316.3_03725001_1 - 0.047 12.2 3.6 0.068 11.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF724 PF05266.12 179316.3_03725001_1 - 0.06 13.0 1.6 0.1 12.3 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF244 PF03112.12 179316.3_03725001_1 - 0.069 12.9 0.8 0.14 11.9 0.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF CCDC-167 PF15188.4 179316.3_03725001_1 - 0.41 10.9 7.1 0.94 9.7 7.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Mnd1 PF03962.13 179316.3_03725001_1 - 0.55 9.9 5.8 0.96 9.1 5.8 1.3 1 0 0 1 1 1 0 Mnd1 family ZapB PF06005.10 179316.3_03725001_1 - 1 9.7 12.0 5.7 7.3 1.3 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Bap31 PF05529.10 179316.3_03725001_1 - 1.1 8.7 4.2 1.8 8.0 4.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like CorA PF01544.16 179316.3_03725001_1 - 1.5 8.0 3.9 2.3 7.3 3.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CLZ PF16526.3 179316.3_03725001_1 - 2 8.7 9.1 0.57 10.4 2.5 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF707 PF05212.10 001035957.3_03724001_3 - 8.2e-135 448.7 0.7 1.1e-134 448.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF707) Peptidase_C1 PF00112.21 001332090.1_03722001_2 - 0.0074 16.3 0.0 0.0093 15.9 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Kelch_1 PF01344.23 101299.4_03725001_3 - 7e-25 86.2 10.0 4.4e-11 42.0 0.0 6.4 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.4 101299.4_03725001_3 - 6e-14 51.6 1.5 1.4e-05 25.1 0.0 5.2 3 1 2 5 5 5 3 Kelch motif Kelch_4 PF13418.4 101299.4_03725001_3 - 5.6e-08 32.5 1.8 0.00078 19.2 0.0 4.3 2 1 2 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.4 101299.4_03725001_3 - 1.3e-07 31.5 4.2 0.0014 18.7 0.0 4.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.13 101299.4_03725001_3 - 1.4e-07 31.0 2.0 0.00056 19.6 0.1 4.8 5 0 0 5 5 5 1 Kelch motif Utp12 PF04003.10 001332165.1_03723001_2 - 5.2e-11 42.7 1.0 9.3e-11 41.9 1.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family HAT_KAT11 PF08214.9 001198086.1_03729001_1 - 9.5e-31 107.2 0.2 6.1e-30 104.5 0.2 2.2 1 1 0 1 1 1 1 Histone acetylation protein zf-TAZ PF02135.14 001198086.1_03729001_1 - 4e-26 91.1 25.9 2.5e-16 59.8 9.2 4.7 4 0 0 4 4 4 2 TAZ zinc finger ZZ PF00569.15 001198086.1_03729001_1 - 3.5e-07 29.8 25.2 1.3e-05 24.8 7.7 4.4 5 0 0 5 5 5 2 Zinc finger, ZZ type PHD PF00628.27 001198086.1_03729001_1 - 9.9e-07 28.4 5.0 9.9e-07 28.4 5.0 5.6 5 0 0 5 5 5 1 PHD-finger zf-C3HC4_3 PF13920.4 001332281.1_03723001_1 - 0.0043 16.7 9.0 0.007 16.1 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001332281.1_03723001_1 - 5.6 6.8 12.3 10 5.9 12.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001332281.1_03723001_1 - 5.9 6.7 13.0 3.1 7.6 6.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.23 001332281.1_03723001_1 - 7.9 6.3 13.0 15 5.5 13.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYDLN_acid PF09538.8 001332281.1_03723001_1 - 8.6 7.0 9.4 1.1 9.9 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) NAD_binding_6 PF08030.10 101781.2_03727001_1 - 6e-52 175.8 0.0 1.1e-51 174.9 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NADPH_Ox PF08414.8 101781.2_03727001_1 - 8.4e-38 128.6 2.5 2.5e-37 127.1 2.5 1.9 1 0 0 1 1 1 1 Respiratory burst NADPH oxidase FAD_binding_8 PF08022.10 101781.2_03727001_1 - 1.5e-31 108.5 0.0 3.3e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.17 101781.2_03727001_1 - 1.9e-17 63.4 3.2 1.9e-17 63.4 3.2 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.4 101781.2_03727001_1 - 1.3e-06 28.6 4.6 0.00028 21.2 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 101781.2_03727001_1 - 2e-05 23.8 1.1 6.3e-05 22.2 0.4 2.2 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.30 101781.2_03727001_1 - 0.0001 21.4 1.0 0.00049 19.3 0.3 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.4 101781.2_03727001_1 - 0.00023 20.7 1.2 0.0015 18.2 0.1 3.0 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.4 101781.2_03727001_1 - 0.71 9.6 5.2 1.3 8.7 0.7 3.4 3 1 0 3 3 3 0 EF-hand domain pair DUF1430 PF07242.9 101781.2_03727001_1 - 0.8 9.9 5.6 0.49 10.6 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) ER_lumen_recept PF00810.16 101852.4_03723001_3 - 1.2e-39 136.3 8.0 1.2e-39 136.3 8.0 1.8 2 0 0 2 2 2 1 ER lumen protein retaining receptor EII-Sor PF03609.12 101852.4_03723001_3 - 0.0017 17.7 3.3 0.14 11.4 0.3 2.5 2 1 0 2 2 2 2 PTS system sorbose-specific iic component C2 PF00168.28 001332437.1_03724001_2 - 8.9e-38 128.6 0.4 1.3e-21 76.6 0.1 2.3 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.3 001332437.1_03724001_2 - 3.6e-20 72.1 0.2 5.2e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain CEP76-C2 PF15627.4 001332437.1_03724001_2 - 0.023 14.1 0.0 0.09 12.2 0.0 1.9 2 0 0 2 2 2 0 CEP76 C2 domain DUF1475 PF07343.9 001084112.2_03723001_1 - 5.6e-65 219.3 17.5 9.3e-65 218.5 17.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1475) SNARE_assoc PF09335.9 001332560.1_03722001_3 - 4.7e-25 88.3 6.3 4.7e-25 88.3 6.3 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Pkinase PF00069.23 001332633.1_03722001_2 - 1.6e-39 135.8 0.0 2.9e-39 134.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001332633.1_03722001_2 - 7.1e-35 120.4 0.0 1.1e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001332633.1_03722001_2 - 0.0067 16.2 0.0 0.052 13.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4505 PF14956.4 001332633.1_03722001_2 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) GTP_EFTU_D2 PF03144.23 001332633.1_03722001_2 - 0.022 15.0 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Elongation factor Tu domain 2 ABC1 PF03109.14 001332633.1_03722001_2 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family adh_short PF00106.23 102292.3_03723001_2 - 7.6e-39 133.1 0.0 9.9e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 102292.3_03723001_2 - 2e-24 86.3 0.0 2.6e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 102292.3_03723001_2 - 4.1e-07 29.9 0.0 8.5e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.4 102292.3_03723001_2 - 0.033 14.0 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.19 102292.3_03723001_2 - 0.043 13.1 0.1 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.16 102292.3_03723001_2 - 0.058 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.13 102292.3_03723001_2 - 0.089 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_11 PF08241.10 102293.4_03722001_1 - 2.3e-10 40.8 0.1 1.2e-09 38.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 102293.4_03722001_1 - 0.00048 20.7 0.0 0.00095 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 102293.4_03722001_1 - 0.00092 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 102293.4_03722001_1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.13 102293.4_03722001_1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF707 PF05212.10 001332654.1_03723001_2 - 9.2e-136 451.8 2.6 1.1e-135 451.5 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF707) PHAT PF09246.8 102321.1_03722001_2 - 0.0024 17.6 0.0 11 5.7 0.0 3.7 1 1 2 4 4 4 2 PHAT PolyA_pol PF01743.18 202195.3_03725001_1 - 5.6e-24 84.8 0.0 1.1e-22 80.7 0.0 2.2 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.5 202195.3_03725001_1 - 2.4e-14 52.7 0.0 4.5e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DOMON PF03351.15 202195.3_03725001_1 - 0.031 14.3 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 DOMON domain GFRP PF06399.11 202195.3_03725001_1 - 0.044 13.6 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) SNARE PF05739.17 001332815.1_03722001_2 - 1.1e-12 47.6 0.7 2.8e-12 46.3 0.7 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-6_N PF09177.9 001332815.1_03722001_2 - 1.1e-09 38.5 2.2 3.2e-08 33.9 0.1 2.6 2 1 0 2 2 2 1 Syntaxin 6, N-terminal Use1 PF09753.7 001332815.1_03722001_2 - 0.004 16.7 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 MCU PF04678.11 001332815.1_03722001_2 - 0.0056 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter SlyX PF04102.10 001332815.1_03722001_2 - 0.35 11.4 3.4 3.2 8.3 0.1 3.1 3 0 0 3 3 3 0 SlyX FlaC_arch PF05377.9 001332815.1_03722001_2 - 6.1 7.2 5.9 10 6.4 0.3 3.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF676 PF05057.12 001332838.1_03725001_3 - 7e-68 228.3 0.0 9.9e-68 227.8 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.5 001332838.1_03725001_3 - 0.00073 20.1 0.3 0.0011 19.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001332838.1_03725001_3 - 0.0048 16.4 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.10 001332838.1_03725001_3 - 0.057 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.10 001332838.1_03725001_3 - 0.081 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase WRKY PF03106.13 102726.3_03723001_2 - 7.6e-27 93.3 4.3 1.5e-26 92.4 4.3 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain HEXIM PF15313.4 102726.3_03723001_2 - 3.6 7.8 8.3 0.3 11.3 0.5 2.5 3 0 0 3 3 3 0 Hexamethylene bis-acetamide-inducible protein YIF1 PF03878.13 102826.4_03723001_2 - 2.6e-57 193.9 0.7 3.5e-57 193.5 0.7 1.1 1 0 0 1 1 1 1 YIF1 Nup160 PF11715.6 001198200.2_03729001_1 - 6.2e-92 308.8 3.5 8.1e-92 308.4 3.5 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 NB-ARC PF00931.20 103079.4_03726001_1 - 4.1e-35 121.1 5.7 3e-28 98.6 0.1 3.0 2 1 1 3 3 3 2 NB-ARC domain RPW8 PF05659.9 103079.4_03726001_1 - 3.5e-12 46.1 0.5 1.1e-11 44.4 0.5 1.8 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 NACHT PF05729.10 103079.4_03726001_1 - 0.0019 18.0 0.0 0.019 14.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.4 103079.4_03726001_1 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 103079.4_03726001_1 - 0.012 15.9 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.5 103079.4_03726001_1 - 0.03 14.6 10.5 10 6.6 0.0 6.1 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) AAA_23 PF13476.4 103079.4_03726001_1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.25 103079.4_03726001_1 - 0.09 13.2 0.2 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter PTRF_SDPR PF15237.4 103079.4_03726001_1 - 0.1 12.1 1.4 0.17 11.4 1.4 1.3 1 0 0 1 1 1 0 PTRF/SDPR family LRR_1 PF00560.31 103079.4_03726001_1 - 6.6 7.5 8.2 1.5e+02 3.4 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat LTP_2 PF14368.4 103312.1_03722001_1 - 1.2e-11 44.5 5.3 1.2e-11 44.5 5.3 1.8 2 0 0 2 2 2 1 Probable lipid transfer Tryp_alpha_amyl PF00234.20 103312.1_03722001_1 - 2.3e-05 24.6 1.7 4.1e-05 23.8 1.7 1.4 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family BPL_LplA_LipB PF03099.17 103366.3_03723001_2 - 1.3e-31 109.0 0.0 2.4e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.15 103366.3_03723001_2 - 4.5e-12 45.5 0.1 7.7e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Pep_M12B_propep PF01562.17 103377.1_03721001_1 - 0.026 14.6 1.7 2.1 8.4 0.5 2.2 1 1 1 2 2 2 0 Reprolysin family propeptide DUF3786 PF12654.5 103377.1_03721001_1 - 0.061 12.8 0.0 27 4.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3786) YafQ_toxin PF15738.3 103377.1_03721001_1 - 0.74 10.0 4.7 8.2 6.7 0.2 2.4 2 1 0 2 2 2 0 Bacterial toxin of type II toxin-antitoxin system, YafQ Peptidase_C48 PF02902.17 001160926.1_03722001_1 - 0.0026 17.5 1.3 0.007 16.1 1.3 1.8 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Aa_trans PF01490.16 103760.3_03724001_2 - 1.8e-100 336.4 32.2 2.1e-100 336.2 32.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.11 103760.3_03724001_2 - 1.1e-07 31.2 5.9 1.1e-07 31.2 5.9 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2583 PF10762.7 103760.3_03724001_2 - 0.067 13.5 1.3 0.43 10.9 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) OppC_N PF12911.5 103760.3_03724001_2 - 6.6 6.7 7.4 0.56 10.1 0.9 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C CitMHS PF03600.14 103868.2_03723001_1 - 3.6e-26 91.9 20.6 3.6e-26 91.9 20.6 1.8 1 1 1 2 2 2 1 Citrate transporter Aminotran_4 PF01063.17 103896.2_03723001_3 - 9.5e-42 143.2 0.0 1.2e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF629 PF04780.10 104121.2_03728001_3 - 1.5e-167 558.0 9.8 2.8e-167 557.0 9.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF629) DUF627 PF04781.10 104121.2_03728001_3 - 1.1e-39 134.6 0.1 2.5e-39 133.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF627) UCH PF00443.27 104121.2_03728001_3 - 1.4e-06 27.8 0.1 3e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4667 PF15700.3 104121.2_03728001_3 - 0.24 11.3 2.5 0.44 10.5 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) TPR_10 PF13374.4 104121.2_03728001_3 - 0.31 10.8 0.9 0.84 9.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_2 PF02230.14 001124003.1_03723001_2 - 0.015 14.9 0.7 0.23 11.1 0.7 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase ODV-E18 PF10717.7 104248.4_03724001_1 - 0.29 10.9 3.5 0.16 11.7 1.2 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Pkinase PF00069.23 104248.4_03724001_3 - 5.8e-55 186.3 0.0 9.5e-32 110.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.15 104248.4_03724001_3 - 9.6e-31 106.9 0.0 1.8e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.4 104248.4_03724001_3 - 0.0045 16.2 0.0 0.045 12.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 104248.4_03724001_3 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.12 104248.4_03724001_3 - 0.042 13.1 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-oxoacid_dh PF00198.21 104300.4_03725001_3 - 3.6e-76 255.5 0.0 4.8e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.20 104300.4_03725001_3 - 1.9e-19 69.1 2.1 3.2e-19 68.4 2.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.15 104300.4_03725001_3 - 9.7e-16 57.7 0.1 2.3e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.4 104300.4_03725001_3 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like Peptidase_M41 PF01434.16 001198298.1_03722001_2 - 0.00023 20.8 0.0 0.039 13.5 0.0 2.4 2 1 0 2 2 2 2 Peptidase family M41 Peptidase_C2 PF00648.19 104411.4_03729001_1 - 1.6e-88 296.5 0.0 2.3e-88 295.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.20 104411.4_03729001_1 - 3.4e-17 62.9 0.0 7.5e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Calpain large subunit, domain III Laminin_G_3 PF13385.4 104411.4_03729001_1 - 4.3e-05 23.6 0.0 9.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.22 104411.4_03729001_1 - 0.034 14.6 0.1 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 Laminin G domain Peptidase_C15 PF01470.15 104547.4_03723001_2 - 1.3e-19 70.9 0.0 5.5e-19 68.9 0.0 1.8 1 1 0 1 1 1 1 Pyroglutamyl peptidase PMP1_2 PF08114.9 001084265.2_03723001_2 - 0.0022 17.5 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 ATPase proteolipid family DUF1049 PF06305.9 001084265.2_03723001_2 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4366 PF14283.4 001084265.2_03723001_2 - 0.028 13.8 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TCP PF03634.11 104592.5_03724001_2 - 1.1e-41 142.9 2.7 3.4e-41 141.2 0.0 2.2 2 0 0 2 2 2 1 TCP family transcription factor DUF4589 PF15252.4 104592.5_03724001_3 - 0.47 10.3 4.5 0.66 9.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Glyco_hydro_28 PF00295.15 104742.4_03725001_3 - 1.3e-77 260.9 10.4 1.1e-67 228.3 8.9 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.5 104742.4_03725001_3 - 3.1e-09 36.9 2.9 0.00033 20.5 0.0 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.4 104742.4_03725001_3 - 0.00079 19.2 8.4 0.0013 18.5 7.7 1.7 2 0 0 2 2 2 1 Right handed beta helix region Pex14_N PF04695.11 104742.4_03725001_3 - 2.3 8.8 6.6 4.2 7.9 6.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nucleoside_tran PF01733.16 104845.3_03723001_1 - 7.2e-34 117.4 3.2 1.2e-33 116.7 3.2 1.3 1 0 0 1 1 1 1 Nucleoside transporter Glyco_hydro_1 PF00232.16 180637.2_03725001_3 - 6.4e-153 509.3 3.6 7.6e-153 509.0 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.16 180637.2_03725001_3 - 0.058 12.7 0.2 1.4 8.2 0.1 2.1 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) ABC_tran PF00005.25 105006.3_03723001_2 - 2.4e-26 92.7 0.0 3.5e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.17 105006.3_03723001_2 - 3.9e-07 29.6 0.1 0.00062 19.1 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.4 105006.3_03723001_2 - 2.2e-06 27.6 1.0 0.0044 16.7 0.3 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.18 105006.3_03723001_2 - 4.6e-05 22.5 0.0 7.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.4 105006.3_03723001_2 - 0.00023 20.7 0.1 0.00047 19.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.4 105006.3_03723001_2 - 0.0015 18.8 0.1 0.0025 18.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.4 105006.3_03723001_2 - 0.0053 16.3 0.1 0.0071 15.9 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.4 105006.3_03723001_2 - 0.0061 17.0 0.1 0.013 15.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.4 105006.3_03723001_2 - 0.032 14.4 0.5 0.092 12.9 0.5 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.14 105006.3_03723001_2 - 0.034 13.9 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.4 105006.3_03723001_2 - 0.095 13.1 0.1 0.18 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.12 105006.3_03723001_2 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.4 105006.3_03723001_2 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.4 105006.3_03723001_2 - 0.19 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.23 001333091.1_03725001_3 - 1.3e-44 152.4 0.0 1.7e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001333091.1_03725001_3 - 2.6e-44 151.3 0.0 3.4e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRRNT_2 PF08263.10 001333091.1_03725001_3 - 2.7e-10 40.2 1.2 2.7e-10 40.2 1.2 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001333091.1_03725001_3 - 1.1e-09 38.2 11.1 0.00022 21.4 1.4 3.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001333091.1_03725001_3 - 2.5e-06 27.0 13.7 0.0021 17.6 2.5 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.31 001333091.1_03725001_3 - 3.7e-05 23.5 10.8 1.6 9.3 0.1 5.4 4 0 0 4 4 4 1 Leucine Rich Repeat APH PF01636.21 001333091.1_03725001_3 - 0.00022 21.1 0.5 0.00045 20.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.4 001333091.1_03725001_3 - 0.049 12.8 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MitoNEET_N PF10660.7 001333091.1_03725001_3 - 0.084 12.8 0.1 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus LRR_6 PF13516.4 001333091.1_03725001_3 - 3.1 7.9 9.1 6.1 7.0 0.3 4.1 4 0 0 4 4 4 0 Leucine Rich repeat p450 PF00067.20 105169.3_03725001_1 - 6.2e-98 328.4 0.0 8e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LEA_2 PF03168.11 105243.4_03723001_1 - 1.8e-11 44.3 0.0 2.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein PMI_typeI PF01238.19 001334269.1_03724001_1 - 1.1e-104 350.4 0.0 1.4e-104 350.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.9 001334269.1_03724001_1 - 2.4e-06 27.0 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.17 001334269.1_03724001_1 - 0.0009 19.0 0.0 0.32 10.8 0.0 2.7 3 0 0 3 3 3 2 AraC-like ligand binding domain EutQ PF06249.10 001334269.1_03724001_1 - 0.071 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Glyco_hydro_31 PF01055.24 105527.5_03727001_1 - 1.2e-145 485.9 0.5 1.6e-145 485.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.3 105527.5_03727001_1 - 3e-36 124.0 0.5 7.1e-36 122.8 0.5 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.4 105527.5_03727001_1 - 6.3e-07 29.5 0.1 3.2e-06 27.2 0.1 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like RBB1NT PF08169.9 105527.5_03727001_2 - 0.15 12.2 0.4 0.28 11.4 0.4 1.3 1 0 0 1 1 1 0 RBB1NT (NUC162) domain PTR2 PF00854.19 105528.5_03725001_1 - 2e-101 339.5 6.9 3.2e-101 338.9 6.9 1.3 1 0 0 1 1 1 1 POT family DUF2304 PF10066.7 105528.5_03725001_1 - 2.1 8.5 12.5 0.37 10.9 1.4 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) peroxidase PF00141.21 105559.4_03723001_1 - 2.1e-68 230.3 0.0 2.6e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase ACT PF01842.23 105575.3_03724001_2 - 7.8e-28 95.8 0.3 8.4e-07 28.5 0.1 4.3 4 0 0 4 4 4 4 ACT domain ACT_4 PF13291.4 105575.3_03724001_2 - 9.4e-10 38.8 0.1 0.044 14.2 0.0 3.8 4 0 0 4 4 4 3 ACT domain ACT_6 PF13740.4 105575.3_03724001_2 - 5.2e-09 35.8 0.9 4.3e-06 26.5 0.1 3.7 4 0 0 4 4 4 2 ACT domain DUF863 PF05904.9 105603.3_03727001_3 - 2.4e-156 522.7 25.1 4.9e-129 432.3 2.0 4.0 1 1 2 3 3 3 3 Plant protein of unknown function (DUF863) Bet_v_1 PF00407.17 001198439.2_03722001_1 - 3.4e-49 166.5 0.3 4.8e-49 166.0 0.3 1.2 1 0 0 1 1 1 1 Pathogenesis-related protein Bet v I family Polyketide_cyc2 PF10604.7 001198439.2_03722001_1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ABC_tran PF00005.25 105802.1_03722001_1 - 8.8e-09 35.9 0.0 1.8e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.21 105802.1_03722001_1 - 0.00037 20.1 1.5 0.00055 19.5 1.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AP2 PF00847.18 105814.4_03723001_2 - 9.8e-11 41.6 1.6 1.6e-10 41.0 1.6 1.3 1 0 0 1 1 1 1 AP2 domain Pkinase PF00069.23 105877.3_03728001_2 - 2.1e-46 158.3 0.0 3e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 105877.3_03728001_2 - 1.7e-40 138.9 0.0 2.2e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.4 105877.3_03728001_2 - 2.1e-32 110.5 59.0 5.9e-07 29.0 0.6 9.9 3 2 10 13 13 13 12 Leucine rich repeat LRR_4 PF12799.5 105877.3_03728001_2 - 6.1e-26 89.8 64.9 1.5e-05 25.1 4.2 11.6 6 2 7 14 14 14 12 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.10 105877.3_03728001_2 - 6.6e-11 42.2 0.1 2.6e-10 40.3 0.1 2.1 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.31 105877.3_03728001_2 - 9.3e-11 40.5 56.3 2.1 9.0 0.7 16.1 16 2 0 16 16 16 7 Leucine Rich Repeat APH PF01636.21 105877.3_03728001_2 - 0.067 13.0 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DnaJ PF00226.29 001124118.1_03722001_3 - 2.3e-17 62.7 0.2 3.9e-17 62.0 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Pex14_N PF04695.11 105919.5_03722001_1 - 0.0056 17.3 0.3 0.0075 16.9 0.3 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec34 PF04136.13 106002.4_03727001_1 - 1.7e-46 157.7 6.6 1.7e-46 157.7 6.6 2.1 2 0 0 2 2 2 1 Sec34-like family DnaB_bind PF10410.7 106002.4_03727001_1 - 0.19 11.8 3.3 0.2 11.8 0.4 2.4 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Pkinase PF00069.23 106028.4_03724001_3 - 5.8e-75 251.9 0.0 7.6e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 106028.4_03724001_3 - 5.2e-31 107.7 0.0 9.1e-31 106.9 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.4 106028.4_03724001_3 - 0.0022 17.2 0.1 0.31 10.2 0.1 2.1 2 0 0 2 2 2 2 Kinase-like SAP PF02037.25 106324.3_03729001_2 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 SAP domain PAT1 PF09770.7 179573.4_03727001_1 - 2.7e-06 25.9 2.8 0.00013 20.3 0.0 3.2 3 1 0 3 3 3 2 Topoisomerase II-associated protein PAT1 Hpt PF01627.21 106659.3_03722001_1 - 1.1e-06 28.6 0.3 2.2e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Hpt domain Aminotran_1_2 PF00155.19 106685.5_03724001_2 - 1e-48 166.3 0.0 1.2e-48 166.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.18 106685.5_03724001_2 - 3.1e-06 25.8 0.0 4.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.11 106685.5_03724001_2 - 0.027 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Allinase Beta_elim_lyase PF01212.19 106685.5_03724001_2 - 0.22 10.7 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Ribosomal_S15 PF00312.20 179583.5_03724001_2 - 1.2e-23 83.0 1.4 2.8e-23 81.8 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 ADIP PF11559.6 179583.5_03724001_2 - 0.0047 16.9 0.6 0.0047 16.9 0.6 1.7 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding C1_2 PF03107.14 001333225.1_03726001_1 - 8.1e-30 102.8 46.6 1.6e-09 37.8 3.5 5.8 6 0 0 6 6 6 4 C1 domain C1_1 PF00130.20 001333225.1_03726001_1 - 0.00032 20.4 34.0 0.27 11.0 0.5 5.4 5 0 0 5 5 5 4 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.27 001333225.1_03726001_1 - 0.0045 16.7 4.7 0.0045 16.7 4.7 5.2 4 1 1 5 5 5 3 PHD-finger Zn_ribbon_17 PF17120.3 001333225.1_03726001_1 - 2.3 7.8 35.4 0.18 11.3 3.6 5.0 5 0 0 5 5 5 0 Zinc-ribbon, C4HC2 type C1_2 PF03107.14 001333225.1_03726001_2 - 2.2e-25 88.6 34.4 1.3e-09 38.1 3.9 3.7 3 0 0 3 3 3 3 C1 domain Kelch_1 PF01344.23 001333628.1_03723001_3 - 2.3e-37 126.2 5.7 5.6e-09 35.3 0.0 5.7 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.4 001333628.1_03723001_3 - 1.5e-29 101.1 6.4 1e-08 35.0 0.0 6.3 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.4 001333628.1_03723001_3 - 8.3e-24 83.2 13.5 5.4e-05 22.9 0.0 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.13 001333628.1_03723001_3 - 3.3e-22 77.4 4.2 0.00017 21.3 0.0 5.9 5 1 0 5 5 5 5 Kelch motif Kelch_3 PF13415.4 001333628.1_03723001_3 - 7.4e-22 77.0 7.0 7.7e-05 22.7 0.0 7.3 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.4 001333628.1_03723001_3 - 3e-21 74.8 8.1 3.3e-05 23.6 0.0 6.1 6 0 0 6 6 6 5 Kelch motif DUF1668 PF07893.11 001333628.1_03723001_3 - 0.00052 19.3 0.1 0.5 9.5 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1668) RAG2 PF03089.12 001333628.1_03723001_3 - 0.028 13.3 0.0 0.51 9.1 0.0 2.6 3 0 0 3 3 3 0 Recombination activating protein 2 DUF3403 PF11883.6 001333968.1_03727001_2 - 8e-16 57.8 1.7 1.9e-15 56.6 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3403) Pkinase_Tyr PF07714.15 001333968.1_03727001_3 - 2.8e-46 157.8 0.0 4.5e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001333968.1_03727001_3 - 1.6e-42 145.6 0.0 2.3e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain S_locus_glycop PF00954.18 001333968.1_03727001_3 - 6.5e-32 110.2 0.2 6.5e-32 110.2 0.2 2.4 2 0 0 2 2 2 1 S-locus glycoprotein domain B_lectin PF01453.22 001333968.1_03727001_3 - 3.1e-26 91.3 1.2 6.2e-26 90.4 1.2 1.5 1 0 0 1 1 1 1 D-mannose binding lectin PAN_2 PF08276.9 001333968.1_03727001_3 - 1.7e-18 66.3 2.2 3.3e-18 65.4 2.2 1.5 1 0 0 1 1 1 1 PAN-like domain APH PF01636.21 001333968.1_03727001_3 - 0.0061 16.4 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family POX PF07526.9 001334689.1_03723001_1 - 2.2e-30 105.9 0.0 3.8e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Associated with HOX Homeobox_KN PF05920.9 001334689.1_03723001_3 - 1.1e-12 47.5 0.7 2.8e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.27 001334689.1_03723001_3 - 2.4e-07 30.3 0.1 2.4e-07 30.3 0.1 2.0 2 0 0 2 2 2 1 Homeobox domain Pkinase_Tyr PF07714.15 001334855.1_03726001_1 - 1.1e-38 132.8 0.0 2.4e-38 131.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001334855.1_03726001_1 - 7e-38 130.4 0.0 8.2e-37 126.8 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Usp PF00582.24 001334855.1_03726001_1 - 9.8e-12 45.4 2.3 1.2e-10 41.9 0.0 2.5 2 0 0 2 2 2 1 Universal stress protein family APH PF01636.21 001334855.1_03726001_1 - 0.021 14.7 0.6 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Bud13 PF09736.7 001334855.1_03726001_1 - 1.3 9.3 7.0 2.7 8.2 7.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex OEP PF02321.16 001334855.1_03726001_1 - 1.4 8.6 13.0 2.2 7.9 13.0 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein IncA PF04156.12 001334855.1_03726001_1 - 4.7 6.8 14.0 9.5 5.8 14.0 1.5 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.13 001334855.1_03726001_1 - 8.9 6.0 11.5 18 5.0 11.5 1.5 1 0 0 1 1 1 0 Mnd1 family EF-hand_1 PF00036.30 001334238.1_03723001_1 - 3.7e-35 116.7 15.5 1.7e-09 36.4 0.6 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.4 001334238.1_03723001_1 - 1.8e-30 105.1 4.7 6.8e-18 64.8 1.1 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.4 001334238.1_03723001_1 - 1.9e-29 101.0 8.4 2.9e-13 49.2 0.3 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.4 001334238.1_03723001_1 - 1.4e-23 80.6 13.2 8.3e-08 31.4 0.1 5.5 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.4 001334238.1_03723001_1 - 1.2e-20 71.9 10.8 5e-06 25.7 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.4 001334238.1_03723001_1 - 2.8e-12 46.6 0.1 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001334238.1_03723001_1 - 3.5e-07 30.0 0.6 0.00013 21.7 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001334238.1_03723001_1 - 8.2e-05 22.8 0.1 0.0054 16.9 0.1 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.11 001334238.1_03723001_1 - 0.00012 21.9 0.0 0.12 12.2 0.0 2.7 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0154) RNA_pol_Rpb4 PF03874.14 001334238.1_03723001_1 - 0.00022 21.4 0.3 0.69 10.1 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb4 EF-hand_11 PF08976.9 001334238.1_03723001_1 - 0.0014 19.3 0.0 0.015 16.1 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.8 001334238.1_03723001_1 - 0.002 18.0 0.3 0.0043 17.0 0.3 1.6 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Poly_export PF02563.14 001334238.1_03723001_1 - 0.086 12.9 0.0 2.9 8.1 0.0 2.6 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.8 001334238.1_03723001_1 - 0.14 12.1 0.1 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 Transcription factor MotA, activation domain CHCH PF06747.11 105643.4_03723001_1 - 2.1e-07 30.8 5.0 3.8e-07 29.9 5.0 1.5 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.7 105643.4_03723001_1 - 0.085 13.0 4.3 0.21 11.8 4.3 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Sld5 PF05916.9 105643.4_03723001_1 - 0.11 12.8 0.0 14 6.1 0.0 2.2 2 0 0 2 2 2 0 GINS complex protein Pkinase_Tyr PF07714.15 001334253.1_03725001_1 - 8.8e-50 169.3 0.0 1.3e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001334253.1_03725001_1 - 3.3e-48 164.2 0.0 5e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WAK_assoc PF14380.4 001334253.1_03725001_1 - 1.4e-12 48.1 6.8 3.7e-12 46.7 6.8 1.7 1 0 0 1 1 1 1 Wall-associated receptor kinase C-terminal GUB_WAK_bind PF13947.4 001334253.1_03725001_1 - 0.00013 22.6 0.6 0.00013 22.6 0.6 3.1 3 0 0 3 3 3 1 Wall-associated receptor kinase galacturonan-binding Kinase-like PF14531.4 001334253.1_03725001_1 - 0.0012 18.1 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001334253.1_03725001_1 - 0.0032 17.3 0.2 0.48 10.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.14 001334253.1_03725001_1 - 0.024 14.6 0.0 0.074 13.1 0.0 1.8 1 0 0 1 1 1 0 ABC1 family EphA2_TM PF14575.4 001334253.1_03725001_1 - 0.064 14.0 0.5 0.66 10.7 0.1 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NB-ARC PF00931.20 001333848.1_03728001_1 - 2.3e-80 269.6 0.1 4.2e-80 268.7 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain LRR_4 PF12799.5 001333848.1_03728001_1 - 3e-07 30.5 24.1 0.16 12.3 0.1 9.0 5 4 5 10 10 10 4 Leucine Rich repeats (2 copies) AAA_22 PF13401.4 001333848.1_03728001_1 - 3e-05 24.2 0.0 0.0001 22.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.4 001333848.1_03728001_1 - 8.1e-05 22.5 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain LRR_8 PF13855.4 001333848.1_03728001_1 - 0.00037 20.1 26.3 0.034 13.8 0.0 7.5 7 2 3 10 10 10 2 Leucine rich repeat AAA_16 PF13191.4 001333848.1_03728001_1 - 0.00041 20.6 0.0 0.00098 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.4 001333848.1_03728001_1 - 0.0061 16.9 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001333848.1_03728001_1 - 0.018 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.4 001333848.1_03728001_1 - 0.021 14.7 2.6 49 4.2 0.0 5.3 4 0 0 4 4 4 0 Leucine Rich repeat AAA PF00004.27 001333848.1_03728001_1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PWI PF01480.15 001333889.1_03728001_3 - 1.1e-12 48.0 2.3 1.9e-12 47.2 2.3 1.4 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.20 001333889.1_03728001_3 - 1.6e-06 27.7 0.0 5.1e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SQHop_cyclase_C PF13243.4 001334859.1_03726001_3 - 2.9e-53 180.9 0.2 6.9e-48 163.2 0.1 2.9 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.4 001334859.1_03726001_3 - 8.3e-38 130.0 0.0 3.9e-34 118.0 0.0 3.8 4 1 1 5 5 5 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.19 001334859.1_03726001_3 - 5.1e-31 106.0 7.6 2.5e-13 49.4 1.8 5.1 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.8 001334859.1_03726001_3 - 1.7e-06 27.4 0.1 0.26 10.4 0.0 4.4 4 0 0 4 4 4 3 Pectic acid lyase Glyco_transf_20 PF00982.19 001333884.1_03728001_1 - 9e-190 631.2 0.0 1.1e-189 630.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.14 001333884.1_03728001_1 - 2.1e-83 278.9 0.0 2.9e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.10 001333884.1_03728001_1 - 3.7e-09 36.6 0.0 0.0002 21.0 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.30 001334163.1_03722001_3 - 7.7e-19 65.6 5.4 5.8e-06 25.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001334163.1_03722001_3 - 1e-15 56.1 4.8 0.0011 18.6 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.4 001334163.1_03722001_3 - 1.1e-14 54.5 1.0 6.1e-09 36.1 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001334163.1_03722001_3 - 3.3e-14 51.5 2.5 5.6e-06 25.5 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.4 001334163.1_03722001_3 - 3.6e-10 39.3 6.8 1.2e-05 24.9 0.2 4.1 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001334163.1_03722001_3 - 0.0031 17.7 0.2 0.013 15.6 0.1 2.0 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_Tyr PF07714.15 001334265.1_03728001_3 - 4.3e-46 157.2 0.0 7e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001334265.1_03728001_3 - 9.6e-44 149.6 0.0 2.1e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GDPD PF03009.15 001334265.1_03728001_3 - 1.2e-29 103.7 0.0 9.2e-23 81.1 0.0 3.2 3 0 0 3 3 3 3 Glycerophosphoryl diester phosphodiesterase family YfmQ PF10787.7 001334265.1_03728001_3 - 0.0074 15.9 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein from bacillus cereus group CARM1 PF11531.6 001334265.1_03728001_3 - 0.055 13.5 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal DUF1794 PF08768.9 001334877.1_03722001_2 - 8.5e-45 152.2 0.0 1.1e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) DUF1958 PF09211.8 001334877.1_03722001_2 - 0.054 13.6 0.1 0.093 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) DUF968 PF06147.9 138939.1_03722120_1 - 0.045 13.9 0.2 0.06 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF968) Chromo PF00385.22 143564.1_03722120_1 - 4e-11 42.5 0.0 6.3e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain F-box PF00646.31 139095.1_03721120_2 - 0.0019 17.9 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 F-box domain zf-RING_11 PF17123.3 143482.1_03721120_2 - 0.0039 16.8 3.0 0.0039 16.8 3.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.5 143482.1_03721120_2 - 0.041 14.0 8.5 0.14 12.3 8.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.4 143482.1_03721120_2 - 0.76 10.0 8.6 1.9 8.7 8.7 1.6 1 1 0 1 1 1 0 Ring finger domain RVT_2 PF07727.12 143406.1_03729120_1 - 1.9e-24 86.2 0.0 2.7e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.24 143406.1_03729120_1 - 3.8e-19 68.9 0.1 6.7e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.4 143406.1_03729120_1 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.12 143406.1_03729120_2 - 1.1e-25 90.3 0.3 1.8e-25 89.6 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.12 143406.1_03729120_3 - 2.1e-12 46.8 0.0 3.3e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_11 PF16622.3 139835.1_03729120_1 - 0.17 11.5 4.0 1 9.0 4.0 2.5 1 0 0 1 1 1 0 zinc-finger C2H2-type MSL1_dimer PF16801.3 139835.1_03729120_2 - 0.27 10.9 3.6 0.61 9.8 3.6 1.5 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Avl9 PF09794.7 139245.1_03721120_2 - 0.13 10.8 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 Pardaxin PF07425.9 139345.1_03722120_2 - 0.055 13.0 0.3 0.13 11.7 0.3 1.6 1 0 0 1 1 1 0 Pardaxin Ins_P5_2-kin PF06090.10 143587.1_03724120_2 - 0.027 13.8 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase DUF2953 PF11167.6 139566.1_03721120_1 - 0.022 14.7 0.1 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) DUF4520 PF15016.4 139659.1_03721120_1 - 0.016 15.2 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) PKcGMP_CC PF16808.3 139706.1_03721120_1 - 0.077 12.7 2.9 0.083 12.6 0.7 2.0 1 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase WD40_alt PF14077.4 139706.1_03721120_1 - 0.084 12.6 1.1 0.084 12.6 1.1 1.4 1 1 0 1 1 1 0 Alternative WD40 repeat motif ANF_receptor PF01094.26 001336389.1_03728001_2 - 2.8e-84 283.1 0.0 3.9e-84 282.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001336389.1_03728001_2 - 4.2e-28 97.9 5.7 8.4e-19 67.7 0.0 2.5 2 0 0 2 2 2 2 Ligand-gated ion channel Peripla_BP_6 PF13458.4 001336389.1_03728001_2 - 1e-26 94.3 0.0 1.5e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein SBP_bac_3 PF00497.18 001336389.1_03728001_2 - 1.7e-20 73.3 0.0 3e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.7 001336389.1_03728001_2 - 7.5e-10 38.9 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Pollen_Ole_e_I PF01190.15 001336114.1_03723001_1 - 0.00021 21.5 0.9 0.00038 20.6 0.9 1.4 1 0 0 1 1 1 1 Pollen proteins Ole e I like FBA_3 PF08268.10 001335779.1_03723001_1 - 7.9e-31 106.5 0.0 1.2e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 F-box associated domain FH2 PF02181.21 001335971.1_03729001_3 - 6.9e-101 337.9 3.7 5.1e-58 196.8 0.3 2.2 1 1 1 2 2 2 2 Formin Homology 2 Domain PTEN_C2 PF10409.7 001335971.1_03729001_3 - 7.9e-29 100.0 0.0 1.4e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein YgaB PF14182.4 001335971.1_03729001_3 - 2 8.8 4.5 1.6 9.1 0.5 2.6 2 0 0 2 2 2 0 YgaB-like protein zf-CCCH PF00642.22 001336416.1_03725001_2 - 2.2e-45 151.6 51.6 3.1e-10 39.6 3.2 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.4 001336416.1_03725001_2 - 1.1e-09 38.3 51.8 8.5e-05 22.8 3.1 5.7 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Torus PF16131.3 001336416.1_03725001_2 - 1.8e-07 31.7 27.4 0.14 12.8 0.1 5.5 4 1 1 5 5 5 5 Torus domain zf-CCCH_3 PF15663.3 001336416.1_03725001_2 - 2.1 8.5 22.4 2.7 8.2 1.0 5.2 5 0 0 5 5 5 0 Zinc-finger containing family Ribosomal_L30_N PF08079.10 126186.4_03723001_2 - 7.9e-29 99.6 13.9 1.7e-28 98.5 13.9 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.18 126186.4_03723001_2 - 5.5e-22 77.3 1.6 5.5e-22 77.3 1.6 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e TFIIB PF00382.17 126189.4_03725001_1 - 8.1e-20 70.5 2.2 5.3e-11 42.3 0.7 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.11 126189.4_03725001_1 - 1.6e-13 50.7 11.5 1.6e-13 50.7 11.5 3.0 2 1 1 3 3 3 1 Brf1-like TBP-binding domain VSP PF03302.11 126189.4_03725001_1 - 0.025 13.3 0.3 0.05 12.3 0.3 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-met PF12874.5 001035872.3_03724001_3 - 3.1e-05 24.1 2.5 0.023 15.0 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.24 001035872.3_03724001_3 - 0.0016 18.7 3.3 0.012 15.9 0.6 4.7 5 1 1 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 001035872.3_03724001_3 - 0.0017 18.2 0.2 0.0017 18.2 0.2 3.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001035872.3_03724001_3 - 0.014 15.6 11.9 0.27 11.5 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.4 001035872.3_03724001_3 - 0.021 15.5 0.4 0.021 15.5 0.4 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger DUF2514 PF10721.7 001035872.3_03724001_3 - 0.061 13.2 4.6 0.11 12.4 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) C1_4 PF07975.10 001035872.3_03724001_3 - 0.062 13.5 8.5 7.6 6.8 0.0 4.0 4 0 0 4 4 4 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.4 001035872.3_03724001_3 - 1.2 9.0 7.9 6.6 6.6 0.6 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Myb_DNA-binding PF00249.29 126267.3_03723001_2 - 2.1e-08 34.0 0.0 2.1e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SNARE_assoc PF09335.9 001335106.1_03725001_1 - 6.2e-20 71.7 10.9 1.7e-19 70.3 10.9 1.8 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF1191 PF06697.10 001335106.1_03725001_1 - 0.23 10.5 1.3 3.7 6.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) DUF1664 PF07889.10 126328.4_03724001_3 - 2.2e-44 150.3 0.1 1.2e-42 144.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) TraF_2 PF13729.4 126328.4_03724001_3 - 0.036 13.3 4.2 0.068 12.4 0.2 2.2 1 1 2 3 3 3 0 F plasmid transfer operon, TraF, protein DUF948 PF06103.9 126328.4_03724001_3 - 0.054 13.6 3.3 2.1 8.5 0.6 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.10 126328.4_03724001_3 - 0.11 12.4 1.9 2.4 8.1 0.2 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.10 126328.4_03724001_3 - 0.25 11.7 3.0 0.71 10.2 0.4 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.3 126328.4_03724001_3 - 0.57 10.4 4.6 15 5.9 0.4 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HSP20 PF00011.19 126354.3_03723001_3 - 2.8e-05 24.1 0.0 0.0015 18.5 0.0 2.3 2 0 0 2 2 2 1 Hsp20/alpha crystallin family BON PF04972.15 126354.3_03723001_3 - 0.022 14.9 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 BON domain RebB PF11747.6 126354.3_03723001_3 - 0.11 12.5 0.3 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Killing trait EMP24_GP25L PF01105.22 126356.2_03722001_2 - 8.3e-28 97.4 0.1 1e-27 97.1 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD mTERF PF02536.12 126357.2_03723001_2 - 9.3e-43 146.3 1.0 9.1e-35 120.0 0.7 2.1 1 1 1 2 2 2 2 mTERF SRF-TF PF00319.16 201682.3_03723001_2 - 4.5e-25 86.7 0.2 4.5e-25 86.7 0.2 1.9 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 201682.3_03723001_2 - 7.5e-24 83.6 11.7 7.5e-24 83.6 11.7 1.7 2 0 0 2 2 2 1 K-box region NAM-associated PF14303.4 001202584.1_03722001_3 - 0.004 17.7 1.7 0.0055 17.2 1.7 1.2 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain DUF1985 PF09331.9 126691.1_03723001_1 - 2.9e-11 43.4 1.8 4.7e-11 42.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1985) PMD PF10536.7 126691.1_03723001_1 - 1e-06 28.1 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Plant mobile domain Ima1_N PF09779.7 126691.1_03723001_1 - 0.2 12.4 1.9 0.47 11.2 1.3 1.8 2 0 0 2 2 2 0 Ima1 N-terminal domain PDCD2_C PF04194.11 126691.1_03723001_1 - 0.5 10.4 3.7 1 9.4 3.7 1.5 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain DUF4283 PF14111.4 126778.1_03724001_1 - 6.8e-12 45.0 0.0 1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4283) zf-CCHC_4 PF14392.4 126778.1_03724001_1 - 1.7e-05 24.3 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.21 126778.1_03724001_1 - 0.02 14.8 2.5 0.037 14.0 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Pentapeptide_2 PF01469.16 126778.1_03724001_1 - 0.11 12.2 4.0 0.19 11.5 4.0 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) zf-CCHC_6 PF15288.4 126778.1_03724001_1 - 0.39 10.5 4.7 0.85 9.4 4.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Dynamin_M PF01031.18 001161044.1_03726001_1 - 3.2e-95 318.5 0.1 6.3e-51 173.1 0.0 2.7 3 0 0 3 3 3 2 Dynamin central region Dynamin_N PF00350.21 001161044.1_03726001_1 - 2.1e-55 187.2 0.0 4.2e-55 186.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.16 001161044.1_03726001_1 - 4.4e-27 93.9 4.5 1e-26 92.8 4.5 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.21 001161044.1_03726001_1 - 4.7e-05 23.3 0.0 9.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.4 001161044.1_03726001_1 - 0.0019 18.4 0.1 0.29 11.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_15 PF13175.4 001161044.1_03726001_1 - 0.057 12.9 5.3 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain GDPD_2 PF13653.4 001161044.1_03726001_1 - 0.14 12.6 0.0 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Aldedh PF00171.20 001084419.1_03725001_1 - 1.9e-138 461.7 0.1 2.2e-138 461.5 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3387 PF11867.6 001084419.1_03725001_1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) XG_FTase PF03254.11 127096.2_03721001_1 - 9.6e-07 27.6 0.1 3.5e-05 22.5 0.0 2.0 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase XG_FTase PF03254.11 127096.2_03721001_3 - 1.2e-14 53.7 0.8 1.5e-14 53.4 0.8 1.1 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase Peptidase_S28 PF05577.10 127364.6_03724001_3 - 1.1e-73 248.4 1.8 3.2e-73 246.9 1.8 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Zn-ribbon_8 PF09723.8 127364.6_03724001_3 - 0.049 13.6 0.5 0.11 12.4 0.5 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DAGK_acc PF00609.17 179649.4_03724001_1 - 1.5e-41 142.2 0.0 2.2e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.22 179649.4_03724001_1 - 4.9e-31 106.8 0.0 7.3e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain UbiA PF01040.16 179653.4_03724001_2 - 4.8e-42 143.9 24.5 6.3e-42 143.5 24.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RALF PF05498.9 127460.2_03721001_1 - 3.4e-14 53.3 1.6 5.2e-14 52.7 1.6 1.3 1 0 0 1 1 1 1 Rapid ALkalinization Factor (RALF) Glyco_hydro_17 PF00332.16 001335636.1_03724001_2 - 1e-68 232.0 0.0 1.3e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.11 001335636.1_03724001_2 - 1.3e-16 60.9 5.8 2.2e-16 60.1 5.8 1.4 1 0 0 1 1 1 1 X8 domain GTP_cyclohydro2 PF00925.18 001335636.1_03724001_2 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase II DUF4270 PF14092.4 001335636.1_03724001_2 - 0.18 10.8 2.8 3.1 6.7 0.0 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4270) WD40 PF00400.30 127773.2_03723001_1 - 4.6e-37 125.2 4.0 6.5e-07 29.8 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 127773.2_03723001_1 - 4e-10 39.7 0.2 0.0082 16.3 0.1 4.9 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 127773.2_03723001_1 - 4.9e-07 28.6 0.2 0.095 11.2 0.0 3.9 3 1 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.9 127773.2_03723001_1 - 0.00012 21.8 0.0 0.017 14.9 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.6 127773.2_03723001_1 - 0.05 11.8 0.0 0.075 11.2 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.3 127773.2_03723001_1 - 0.082 11.7 0.2 1.2 7.8 0.1 2.6 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PPR_2 PF13041.4 127805.3_03725001_2 - 3e-63 209.7 15.1 2.2e-10 40.4 0.0 11.1 6 3 6 12 12 12 10 PPR repeat family PPR PF01535.18 127805.3_03725001_2 - 1.2e-61 200.6 26.9 6.5e-08 32.2 0.0 13.8 14 0 0 14 14 14 11 PPR repeat PPR_1 PF12854.5 127805.3_03725001_2 - 2e-35 120.0 6.5 5.1e-06 26.0 0.0 11.6 12 0 0 12 12 12 9 PPR repeat PPR_3 PF13812.4 127805.3_03725001_2 - 1.6e-19 69.6 0.0 0.0023 17.9 0.0 8.1 3 1 7 10 10 10 6 Pentatricopeptide repeat domain PPR_long PF17177.2 127805.3_03725001_2 - 1e-09 38.0 0.0 0.009 15.3 0.0 4.2 1 1 1 3 3 3 3 Pentacotripeptide-repeat region of PROPR DYW_deaminase PF14432.4 127805.3_03725001_2 - 8.3e-05 22.3 0.0 0.0038 17.0 0.0 2.8 3 0 0 3 3 3 1 DYW family of nucleic acid deaminases TPR_14 PF13428.4 127805.3_03725001_2 - 0.0049 17.4 0.0 46 5.1 0.0 5.8 9 0 0 9 9 9 0 Tetratricopeptide repeat Kinesin PF00225.21 127826.5_03727001_1 - 5.4e-112 373.9 0.4 5.4e-112 373.9 0.4 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.3 127826.5_03727001_1 - 1e-49 168.2 0.3 1e-49 168.2 0.3 2.9 3 1 0 3 3 3 1 Microtubule binding Malectin PF11721.6 127826.5_03727001_1 - 1.5e-17 64.1 0.1 1.3e-16 61.0 0.0 2.5 2 0 0 2 2 2 1 Di-glucose binding within endoplasmic reticulum MAD PF05557.11 127826.5_03727001_1 - 0.00051 18.4 38.6 0.00051 18.4 38.6 2.4 2 0 0 2 2 2 1 Mitotic checkpoint protein BRE1 PF08647.9 127826.5_03727001_1 - 0.0012 18.7 17.9 0.0012 18.7 17.9 4.8 3 1 1 4 4 3 1 BRE1 E3 ubiquitin ligase Viral_P18 PF04521.11 127826.5_03727001_1 - 0.016 14.8 1.2 0.37 10.4 2.2 2.8 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein MbeD_MobD PF04899.10 127826.5_03727001_1 - 0.017 15.1 0.4 0.017 15.1 0.4 5.4 3 2 1 5 5 4 0 MbeD/MobD like Reo_sigmaC PF04582.10 127826.5_03727001_1 - 0.088 12.1 15.0 0.13 11.5 5.0 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.10 127826.5_03727001_1 - 1.3 8.9 7.0 1 9.3 1.9 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.10 127826.5_03727001_1 - 1.4 8.7 40.4 0.032 14.1 0.6 6.0 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) Lebercilin PF15619.4 127826.5_03727001_1 - 8 5.9 71.1 2.1 7.8 16.2 4.6 2 2 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Peptidase_S10 PF00450.20 127865.3_03725001_1 - 5e-130 434.5 1.7 5.8e-130 434.3 1.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase UCR_hinge PF02320.14 127865.3_03725001_1 - 0.049 13.7 0.7 0.1 12.7 0.7 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Abhydrolase_6 PF12697.5 179711.2_03722001_2 - 1.5e-12 48.5 0.0 3.4e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 179711.2_03722001_2 - 8.5e-07 28.7 0.2 8.4e-06 25.5 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 179711.2_03722001_2 - 0.00019 20.7 1.0 0.004 16.3 0.1 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.11 179711.2_03722001_2 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.11 179711.2_03722001_2 - 0.078 12.7 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF3341 PF11821.6 001335316.1_03721001_1 - 0.036 13.6 0.3 0.038 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Rieske PF00355.24 128041.4_03724001_1 - 4.8e-21 74.4 0.0 9.1e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.10 128041.4_03724001_1 - 2.2e-19 69.3 0.0 5.7e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Pheophorbide a oxygenase ABC_membrane PF00664.21 001335347.1_03729001_3 - 1.3e-56 192.2 38.7 2.5e-40 138.7 13.2 3.9 3 1 1 4 4 3 2 ABC transporter transmembrane region ABC_tran PF00005.25 001335347.1_03729001_3 - 1.9e-48 164.3 0.0 6.3e-29 101.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.17 001335347.1_03729001_3 - 2e-09 37.1 2.5 0.18 11.1 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.21 001335347.1_03729001_3 - 2.8e-07 30.6 2.8 0.0037 17.2 0.4 2.8 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.21 001335347.1_03729001_3 - 4.3e-07 29.9 1.3 0.0084 16.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.14 001335347.1_03729001_3 - 3.9e-06 26.8 0.1 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.4 001335347.1_03729001_3 - 2.2e-05 24.0 0.6 0.093 12.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.4 001335347.1_03729001_3 - 0.0001 22.6 0.3 0.27 11.5 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.4 001335347.1_03729001_3 - 0.00054 19.7 0.8 0.68 9.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.4 001335347.1_03729001_3 - 0.00075 19.7 1.0 0.24 11.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.16 001335347.1_03729001_3 - 0.0013 18.0 0.2 0.52 9.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.15 001335347.1_03729001_3 - 0.0037 17.2 2.6 0.1 12.5 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.4 001335347.1_03729001_3 - 0.0053 17.2 0.5 0.53 10.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain IIGP PF05049.11 001335347.1_03729001_3 - 0.0054 15.7 0.4 0.56 9.1 0.1 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Vps51 PF08700.9 001335347.1_03729001_3 - 0.018 15.0 0.1 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Vps51/Vps67 TsaE PF02367.15 001335347.1_03729001_3 - 0.031 14.2 0.1 3.1 7.7 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.17 001335347.1_03729001_3 - 0.033 13.6 1.4 0.31 10.5 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.11 001335347.1_03729001_3 - 0.043 13.9 0.4 5.7 7.1 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.7 001335347.1_03729001_3 - 0.056 12.2 0.6 3.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.10 001335347.1_03729001_3 - 0.13 12.0 0.4 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Septin PF00735.16 001335347.1_03729001_3 - 0.19 10.8 0.8 7.7 5.5 0.1 2.3 2 0 0 2 2 2 0 Septin T2SSE PF00437.18 001335347.1_03729001_3 - 0.23 10.4 0.7 6 5.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AIG1 PF04548.14 001335347.1_03729001_3 - 0.23 10.6 1.1 13 4.9 0.1 2.3 2 0 0 2 2 2 0 AIG1 family Defensin_2 PF01097.16 001036335.2_03721001_3 - 0.024 14.4 6.7 0.048 13.5 6.7 1.4 1 0 0 1 1 1 0 Arthropod defensin Gamma-thionin PF00304.18 001036335.2_03721001_3 - 0.032 14.4 9.4 0.051 13.7 9.4 1.3 1 0 0 1 1 1 0 Gamma-thionin family Toxin_3 PF00537.16 001036335.2_03721001_3 - 0.15 12.1 8.4 0.2 11.8 8.4 1.2 1 0 0 1 1 1 0 Scorpion toxin-like domain AP2 PF00847.18 128142.4_03723001_3 - 1.3e-10 41.2 0.8 3.1e-10 40.0 0.8 1.7 1 0 0 1 1 1 1 AP2 domain SR-25 PF10500.7 128142.4_03723001_3 - 0.0092 15.5 9.6 0.0092 15.5 9.6 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein FAE1_CUT1_RppA PF08392.10 128221.6_03724001_3 - 1.4e-138 460.9 0.0 1.8e-138 460.6 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.8 128221.6_03724001_3 - 7.2e-11 42.0 0.0 2.3e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.13 128221.6_03724001_3 - 6.6e-09 35.8 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.8 128221.6_03724001_3 - 0.058 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Peptidase_S10 PF00450.20 201822.1_03723001_3 - 8.9e-59 199.8 0.0 1.2e-58 199.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.6 201822.1_03723001_3 - 0.00041 19.5 0.0 0.00093 18.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1725 PF08333.9 201822.1_03723001_3 - 6.2 6.5 8.1 0.16 11.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Rhomboid PF01694.20 128462.4_03724001_1 - 1.1e-42 145.4 19.0 5.1e-42 143.3 19.5 1.9 2 0 0 2 2 2 1 Rhomboid family Mgm101p PF06420.10 128565.5_03725001_1 - 0.0054 16.1 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 ARL6IP6 PF15062.4 128565.5_03725001_1 - 0.081 12.9 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix PPR_2 PF13041.4 128565.5_03725001_2 - 5e-07 29.7 2.3 0.079 13.0 0.0 4.8 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.18 128565.5_03725001_2 - 0.00098 19.1 10.9 0.058 13.5 0.0 5.2 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.2 128565.5_03725001_2 - 0.0018 17.5 0.1 2.5 7.3 0.0 3.1 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PROPR MA3 PF02847.15 128565.5_03725001_2 - 0.061 13.2 0.0 40 4.1 0.0 3.5 4 0 0 4 4 4 0 MA3 domain PPR_3 PF13812.4 128565.5_03725001_2 - 0.075 13.0 0.0 12 6.0 0.0 3.8 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Cofilin_ADF PF00241.18 128676.5_03723001_3 - 1.4e-35 122.1 0.7 1.9e-35 121.7 0.7 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HAGH_C PF16123.3 128692.5_03724001_1 - 5.4e-23 81.2 0.1 1.2e-22 80.0 0.1 1.7 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.25 128692.5_03724001_1 - 2.7e-18 66.5 2.6 1.8e-17 63.9 2.6 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.5 128692.5_03724001_1 - 0.004 16.5 0.2 0.0071 15.7 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Myc_N PF01056.16 128911.3_03722001_1 - 0.00018 21.4 3.5 0.00024 21.0 3.5 1.1 1 0 0 1 1 1 1 Myc amino-terminal region TFIIE-A_C PF11521.6 128911.3_03722001_1 - 0.0017 18.5 8.3 0.0028 17.8 8.3 1.3 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha WW PF00397.24 128911.3_03722001_1 - 0.0027 17.5 1.2 0.0031 17.3 0.0 1.7 2 0 0 2 2 2 1 WW domain Na_trans_assoc PF06512.11 128911.3_03722001_1 - 0.0072 16.6 4.0 0.01 16.1 4.0 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated CENP-B_dimeris PF09026.8 128911.3_03722001_1 - 0.0092 16.2 3.1 0.015 15.5 3.1 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DAP PF15228.4 128911.3_03722001_1 - 0.13 13.2 0.2 0.29 12.1 0.2 1.5 1 0 0 1 1 1 0 Death-associated protein Nop14 PF04147.10 128911.3_03722001_1 - 0.31 9.1 6.5 0.32 9.0 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family MIP PF00230.18 129274.4_03723001_1 - 1e-84 283.6 11.7 1.3e-84 283.3 11.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein SfLAP PF11139.6 129274.4_03723001_1 - 0.036 13.4 3.3 1.2 8.4 0.0 2.8 2 1 1 3 3 3 0 Sap, sulfolipid-1-addressing protein WRKY PF03106.13 129282.4_03724001_1 - 3.6e-50 168.0 19.0 1.2e-25 89.5 3.0 2.7 3 0 0 3 3 3 2 WRKY DNA -binding domain FAR1 PF03101.13 129282.4_03724001_1 - 0.13 12.9 4.8 0.43 11.2 0.4 2.8 2 1 0 2 2 2 0 FAR1 DNA-binding domain Aa_trans PF01490.16 129368.3_03725001_2 - 3.1e-86 289.5 28.7 4.4e-86 289.0 28.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein peroxidase PF00141.21 129461.3_03723001_1 - 4.8e-66 222.6 0.0 6e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase PTA_PTB PF01515.17 129461.3_03723001_1 - 0.031 13.5 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase HLH PF00010.24 201941.2_03724001_2 - 6e-07 29.2 0.4 6e-07 29.2 0.4 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain C1_2 PF03107.14 129884.4_03724001_2 - 3.4e-56 187.2 103.5 3.4e-10 39.9 6.4 9.3 9 0 0 9 9 9 8 C1 domain C1_1 PF00130.20 129884.4_03724001_2 - 2.7e-07 30.2 87.1 0.00029 20.5 2.8 9.8 8 1 2 10 10 10 7 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.27 129884.4_03724001_2 - 1.1e-05 25.0 79.7 0.0048 16.6 5.0 9.3 5 3 3 8 8 8 4 PHD-finger IF-2B PF01008.15 129970.4_03723001_3 - 2.7e-85 285.8 0.1 3.2e-85 285.6 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Glyco_transf_90 PF05686.10 130146.4_03725001_3 - 1.6e-194 646.2 4.7 2.1e-194 645.8 4.7 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 WRKY PF03106.13 130175.3_03722001_1 - 7e-26 90.2 4.9 1.4e-25 89.3 4.9 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain A_thal_3526 PF09713.8 001125064.1_03724001_1 - 2.4e-26 91.6 0.1 4e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) Nop PF01798.16 001125064.1_03724001_1 - 0.01 15.2 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Thioredoxin PF00085.18 130315.5_03724001_1 - 7.6e-68 224.9 0.2 9.6e-33 112.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.10 130315.5_03724001_1 - 1.5e-22 80.1 0.5 3.2e-22 79.1 0.5 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.4 130315.5_03724001_1 - 1.4e-16 60.8 0.2 7.3e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.11 130315.5_03724001_1 - 1e-15 57.7 0.0 1.9e-07 30.6 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.19 130315.5_03724001_1 - 1e-09 38.3 0.5 0.00099 18.9 0.1 3.0 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.4 130315.5_03724001_1 - 5.5e-08 32.9 0.0 0.02 15.1 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.4 130315.5_03724001_1 - 4.3e-07 29.9 0.0 0.0035 17.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.4 130315.5_03724001_1 - 2.3e-06 27.6 0.1 0.0038 17.1 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like domain Redoxin PF08534.8 130315.5_03724001_1 - 0.00014 21.4 1.5 0.49 9.9 0.1 2.6 2 1 0 2 2 2 2 Redoxin HyaE PF07449.9 130315.5_03724001_1 - 0.0022 17.8 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.4 130315.5_03724001_1 - 0.24 11.4 1.4 22 5.0 0.2 2.7 2 0 0 2 2 2 0 Thioredoxin MFS_1 PF07690.14 126910.3_03725001_1 - 2.7e-37 128.4 43.5 3.8e-32 111.4 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 126910.3_03725001_1 - 0.065 11.9 36.3 0.02 13.7 13.7 3.1 1 1 1 3 3 3 0 Sugar (and other) transporter TPT PF03151.14 001335397.1_03723001_3 - 1.8e-08 34.0 9.9 2.5e-08 33.5 9.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.18 001335397.1_03723001_3 - 7e-05 22.9 17.2 0.0023 18.0 1.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF456 PF04306.11 001335397.1_03723001_3 - 0.013 15.7 1.1 0.013 15.7 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF456) TMEM234 PF10639.7 001335397.1_03723001_3 - 1.2 9.1 9.9 1.2 9.1 0.9 3.2 3 1 0 3 3 3 0 Putative transmembrane family 234 Glyco_hydro_16 PF00722.19 001335429.1_03723001_2 - 1e-48 165.0 0.1 1.8e-48 164.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 XET_C PF06955.10 001335429.1_03723001_2 - 4.2e-16 58.5 3.2 7.3e-16 57.7 3.2 1.4 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus PPR_long PF17177.2 001335484.1_03725001_1 - 6.8e-72 241.1 0.2 9.8e-72 240.6 0.2 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PROPR PRORP PF16953.3 001335484.1_03725001_1 - 2.7e-58 197.2 0.6 3.6e-58 196.8 0.6 1.2 1 0 0 1 1 1 1 Protein-only RNase P RNase_Zc3h12a PF11977.6 001335484.1_03725001_1 - 9e-07 28.7 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_2 PF13041.4 001335484.1_03725001_1 - 0.034 14.2 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 PPR repeat family DUF866 PF05907.11 001335484.1_03725001_1 - 0.055 13.2 1.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) PPR_3 PF13812.4 001335484.1_03725001_1 - 0.069 13.1 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Peptidase_S8 PF00082.20 001335625.1_03726001_2 - 3.7e-44 151.1 0.1 5.2e-44 150.6 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.14 001335625.1_03726001_2 - 9.3e-21 74.1 0.0 1.7e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 fn3_5 PF06280.10 001335625.1_03726001_2 - 8.6e-14 52.1 0.4 2e-13 50.9 0.4 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.20 001335625.1_03726001_2 - 1.1e-05 25.3 1.7 1.7e-05 24.7 0.0 2.2 3 0 0 3 3 3 1 PA domain FixG_C PF11614.6 001335625.1_03726001_2 - 0.16 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase RabGAP-TBC PF00566.16 001335628.1_03726001_1 - 8.8e-23 81.0 4.6 1.8e-21 76.6 1.2 3.4 2 1 0 2 2 2 1 Rab-GTPase-TBC domain BPL_C PF02237.15 001336015.1_03725001_1 - 4.2e-11 42.4 0.1 6.3e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_LplA_LipB PF03099.17 001336015.1_03725001_3 - 3.7e-34 117.3 0.0 6.2e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PITH PF06201.11 001336031.1_03723001_1 - 2.3e-38 131.7 0.0 2.9e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain DUF1771 PF08590.8 001336049.1_03726001_1 - 3.8e-17 62.3 9.0 7.4e-17 61.3 9.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) PAM2 PF07145.13 001336049.1_03726001_1 - 0.00086 18.7 0.3 0.002 17.5 0.3 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Smr PF01713.19 001336049.1_03726001_3 - 4.6e-06 26.8 0.2 7.2e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 Smr domain Pkinase PF00069.23 001336180.1_03724001_1 - 1.8e-44 151.9 0.0 2.6e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001336180.1_03724001_1 - 1.2e-43 149.1 0.0 1.9e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_2 PF13923.4 001336418.1_03725001_2 - 4.6e-11 42.2 14.5 2.1e-10 40.2 14.5 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001336418.1_03725001_2 - 4.4e-08 32.7 15.3 1.6e-07 30.9 15.3 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001336418.1_03725001_2 - 6.6e-08 32.2 11.7 2.2e-07 30.5 11.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001336418.1_03725001_2 - 1.1e-05 25.4 13.5 1.1e-05 25.4 13.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.4 001336418.1_03725001_2 - 4.4e-05 23.2 13.3 0.00015 21.5 13.3 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001336418.1_03725001_2 - 0.00015 21.5 13.3 0.0011 18.8 13.3 2.6 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.13 001336418.1_03725001_2 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.4 001336418.1_03725001_2 - 0.0025 17.8 12.9 0.0025 17.8 12.9 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.4 001336418.1_03725001_2 - 0.15 11.8 16.1 0.021 14.5 10.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.4 001336418.1_03725001_2 - 0.41 10.3 13.3 3.9 7.2 0.0 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.6 001336418.1_03725001_2 - 0.83 9.4 7.1 1.7 8.4 7.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.30 001336418.1_03725001_3 - 1.5e-21 76.1 12.5 1.9e-05 25.2 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat WD40_like PF17005.3 001336418.1_03725001_3 - 2.4e-08 33.6 0.0 2.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.5 001336418.1_03725001_3 - 2e-05 24.6 1.9 8.6 6.6 0.0 5.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Baculo_p24 PF05073.10 001336418.1_03725001_3 - 0.49 10.0 4.6 1.1 8.9 0.2 2.7 3 0 0 3 3 3 0 Baculovirus P24 capsid protein zf-RING_2 PF13639.4 001336638.1_03729001_2 - 4.4e-12 45.9 3.7 1.5e-11 44.2 3.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.4 001336638.1_03729001_2 - 2e-09 37.0 3.7 4.6e-09 35.8 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001336638.1_03729001_2 - 1.4e-08 34.3 4.4 3.8e-08 32.9 4.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001336638.1_03729001_2 - 5.1e-08 33.0 5.2 1.6e-07 31.4 5.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001336638.1_03729001_2 - 1.7e-06 27.5 0.6 5.8e-06 25.8 0.6 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.4 001336638.1_03729001_2 - 3.5e-05 23.6 3.8 0.00011 22.0 3.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 001336638.1_03729001_2 - 0.00026 20.7 3.6 0.00069 19.3 3.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001336638.1_03729001_2 - 0.00031 20.5 4.5 0.00075 19.3 4.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.3 001336638.1_03729001_2 - 0.028 13.9 3.6 0.091 12.3 3.6 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.5 001336638.1_03729001_2 - 0.053 13.4 2.5 0.14 12.1 2.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.5 001336638.1_03729001_2 - 0.21 11.6 6.4 0.47 10.5 6.4 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.4 001336638.1_03729001_2 - 0.22 11.3 3.2 0.58 9.9 3.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 WEMBL PF05701.9 001336697.1_03724001_1 - 6.5e-41 140.5 54.2 4.5e-28 98.1 51.9 2.2 1 1 1 2 2 2 2 Weak chloroplast movement under blue light BTB PF00651.29 001336795.1_03724001_1 - 3.4e-33 114.0 0.5 2.1e-32 111.5 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.24 001336795.1_03724001_1 - 0.00013 21.9 0.0 0.00042 20.3 0.0 1.8 1 1 0 1 1 1 1 MATH domain PLAC8 PF04749.15 001336880.1_03722001_2 - 4.1e-26 91.7 17.1 6.8e-26 91.0 17.1 1.3 1 0 0 1 1 1 1 PLAC8 family RNA_pol_Rpb5_C PF01191.17 001336902.1_03724001_3 - 1.4e-23 82.4 0.2 2.2e-23 81.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.12 001336902.1_03724001_3 - 4.6e-22 78.2 0.0 7.6e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain ASCH PF04266.12 001337031.1_03724001_2 - 0.016 15.7 0.1 0.15 12.5 0.0 2.3 1 1 1 2 2 2 0 ASCH domain UPF0565 PF10561.7 001337100.1_03723001_2 - 1.6e-17 63.6 0.9 4.6e-13 48.9 0.1 2.5 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 Ran-binding PF05508.9 001337100.1_03723001_2 - 0.079 11.8 0.3 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 RanGTP-binding protein Bestrophin PF01062.19 001337157.1_03724001_1 - 7.4e-33 114.0 0.6 1.2e-32 113.3 0.6 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DM4_12 PF07841.11 143619.1_03723120_1 - 0.082 13.5 0.1 0.23 12.0 0.0 1.7 2 0 0 2 2 2 0 DM4/DM12 family zf-Sec23_Sec24 PF04810.13 140081.1_03721120_1 - 0.0015 18.4 24.4 0.16 11.9 0.4 4.4 4 1 1 5 5 5 3 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.3 140081.1_03721120_1 - 0.068 12.4 5.0 7.5 5.9 0.1 3.4 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Di19 PF05605.10 140081.1_03721120_1 - 0.085 13.0 9.4 6.2 7.0 0.1 3.4 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_17 PF17120.3 140081.1_03721120_1 - 5.8 6.5 17.8 9 5.9 0.4 3.4 2 1 1 3 3 3 0 Zinc-ribbon, C4HC2 type FYVE_2 PF02318.14 140081.1_03721120_1 - 6.7 6.8 15.8 15 5.7 0.3 2.4 2 1 0 2 2 2 0 FYVE-type zinc finger DUF4961 PF16328.3 140279.1_03721120_3 - 0.15 11.2 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) Invas_SpaK PF03519.12 140304.1_03721120_3 - 0.13 12.3 0.1 0.22 11.5 0.1 1.2 1 0 0 1 1 1 0 Invasion protein B family DUF3285 PF11688.6 140333.1_03721120_1 - 0.0061 16.3 0.0 0.0096 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3285) DEC-1_N PF04625.11 140731.1_03723120_1 - 5.4 5.8 5.9 7.3 5.3 5.9 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region OAD_gamma PF04277.11 140731.1_03723120_1 - 8.7 6.9 0.0 8.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4710 PF15828.3 140779.1_03723120_1 - 7.5 6.6 18.3 13 5.9 18.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF4710 PF15828.3 140779.1_03723120_3 - 6.9 6.7 6.2 2.6 8.1 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) AKAP7_NLS PF10469.7 001338212.1_03724001_1 - 1.1e-70 237.6 0.0 1.6e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.27 001338212.1_03724001_1 - 2.2e-06 27.3 0.5 4.2e-06 26.4 0.5 1.5 1 0 0 1 1 1 1 KH domain ATP-grasp_3 PF02655.12 001338212.1_03724001_1 - 0.034 14.0 0.9 0.072 13.0 0.9 1.5 1 0 0 1 1 1 0 ATP-grasp domain LigT_PEase PF02834.14 001338212.1_03724001_1 - 0.059 13.4 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 LigT like Phosphoesterase HAD_2 PF13419.4 001340135.1_03722001_1 - 1.8e-07 31.3 0.0 3.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.24 001340135.1_03722001_1 - 1.3e-06 28.7 0.0 2.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.4 001340135.1_03722001_1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like p450 PF00067.20 001340071.1_03723001_1 - 2.6e-16 59.3 0.0 1.5e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Helicase_C PF00271.29 111072.2_03726001_2 - 3.7e-23 81.9 0.4 8e-20 71.1 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.27 111072.2_03726001_2 - 4.4e-18 65.5 0.5 3.9e-16 59.2 0.1 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase CarD_CdnL_TRCF PF02559.14 111072.2_03726001_2 - 3.8e-14 53.0 0.0 1.4e-13 51.2 0.0 2.1 1 0 0 1 1 1 1 CarD-like/TRCF domain ResIII PF04851.13 111072.2_03726001_2 - 4.9e-08 33.0 0.0 6.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TRCF PF03461.13 111072.2_03726001_2 - 1.3e-05 25.3 0.2 6.4e-05 23.1 0.3 2.1 2 0 0 2 2 2 1 TRCF domain E3_UbLigase_R4 PF13764.4 111093.2_03729001_1 - 0 1098.3 0.1 0 1094.9 0.0 2.1 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.15 111093.2_03729001_1 - 2.4e-09 36.7 8.4 2.4e-09 36.7 8.4 3.1 3 0 0 3 3 3 1 Zinc finger, ZZ type Drf_FH3 PF06367.14 111093.2_03729001_1 - 0.061 12.8 0.0 0.31 10.5 0.0 2.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain PAP2 PF01569.19 001084627.1_03723001_1 - 4.3e-30 104.1 0.7 4.3e-30 104.1 0.7 2.6 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.4 001084627.1_03723001_1 - 5.7 6.4 22.6 0.0099 15.5 8.7 3.2 2 1 0 2 2 2 0 PAP2 superfamily Atrophin-1 PF03154.13 111205.4_03724001_1 - 0.25 9.5 13.0 0.34 9.0 13.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 111205.4_03724001_1 - 4 7.3 14.7 0.75 9.7 8.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 111205.4_03724001_2 - 0.083 11.0 16.0 0.11 10.7 16.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.4 111205.4_03724001_2 - 0.26 11.1 10.9 0.42 10.5 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) LUC7 PF03194.13 111205.4_03724001_3 - 4.2e-65 219.7 13.4 5.8e-39 134.1 3.2 3.2 2 1 1 4 4 4 2 LUC7 N_terminus PRP38_assoc PF12871.5 111205.4_03724001_3 - 1.1 9.7 83.7 6.8 7.2 11.5 3.4 2 1 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term ANF_receptor PF01094.26 001337503.1_03726001_3 - 4.6e-57 193.6 1.4 7.3e-57 192.9 1.4 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001337503.1_03726001_3 - 2.3e-26 92.3 9.2 1.4e-25 89.7 9.2 2.2 1 1 0 1 1 1 1 Ligand-gated ion channel Peripla_BP_6 PF13458.4 001337503.1_03726001_3 - 1.1e-22 81.0 0.0 1.8e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein SBP_bac_3 PF00497.18 001337503.1_03726001_3 - 1.9e-07 30.6 0.0 8.5e-07 28.5 0.0 2.1 3 0 0 3 3 3 1 Bacterial extracellular solute-binding proteins, family 3 DUF440 PF04269.10 001337503.1_03726001_3 - 0.13 12.4 0.3 4.5 7.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF440 DUF868 PF05910.10 111358.4_03724001_2 - 5.4e-97 324.6 0.4 7.1e-97 324.2 0.4 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF868) zf-ANAPC11 PF12861.5 001337617.1_03723001_3 - 4.1e-38 129.2 14.2 6.6e-38 128.5 14.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.5 001337617.1_03723001_3 - 2.6e-21 75.5 16.4 5.2e-21 74.6 16.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.4 001337617.1_03723001_3 - 3.4e-05 23.9 18.8 0.00027 21.0 18.8 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.4 001337617.1_03723001_3 - 0.02 14.9 6.9 0.061 13.4 2.5 3.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.4 001337617.1_03723001_3 - 0.91 9.4 15.9 56 3.7 17.0 2.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.6 001337617.1_03723001_3 - 1.2 8.9 6.5 2.3 8.0 6.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.4 001337617.1_03723001_3 - 6.8 6.5 14.6 2.1e+02 1.8 15.0 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.3 001337617.1_03723001_3 - 8.5 6.1 14.5 16 5.1 12.2 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-HC3 PF16827.3 001337622.1_03724001_1 - 0.0036 17.3 0.6 27 4.9 0.0 4.1 4 0 0 4 4 4 3 zinc-finger Filamin PF00630.17 111490.4_03726001_2 - 0.0085 16.8 0.0 0.022 15.4 0.0 1.6 2 0 0 2 2 2 1 Filamin/ABP280 repeat RINGv PF12906.5 111508.3_03724001_3 - 5.7e-13 48.6 11.3 9.4e-13 47.9 11.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.4 111508.3_03724001_3 - 0.0032 17.6 8.6 0.0072 16.4 8.6 1.6 1 0 0 1 1 1 1 Ring finger domain DUF4796 PF16044.3 111508.3_03724001_3 - 0.021 14.3 0.2 0.043 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) zf-RING-like PF08746.9 111508.3_03724001_3 - 5.5 7.3 9.4 10 6.4 9.4 1.5 1 0 0 1 1 1 0 RING-like domain Tub PF01167.16 111513.4_03724001_3 - 7.2e-90 300.3 0.0 9.7e-90 299.9 0.0 1.2 1 0 0 1 1 1 1 Tub family F-box PF00646.31 111513.4_03724001_3 - 1.4e-13 50.2 0.2 3.2e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 111513.4_03724001_3 - 0.00053 19.7 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF3527 PF12043.6 111513.4_03724001_3 - 0.019 14.4 0.3 0.076 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) Cas1_AcylT PF07779.10 111531.5_03725001_2 - 2.5e-92 310.2 27.1 3.5e-92 309.7 27.1 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Alba PF01918.19 001337687.1_03724001_2 - 1.7e-16 59.7 1.2 2.7e-16 59.0 1.2 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.6 001337687.1_03724001_2 - 0.00049 19.9 0.0 0.00076 19.3 0.0 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P HMA PF00403.24 111639.1_03722001_3 - 0.0045 17.3 0.2 0.0076 16.5 0.2 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Trypan_PARP PF05887.9 111639.1_03722001_3 - 0.28 11.1 18.1 0.44 10.4 18.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Exo70 PF03081.13 111787.2_03726001_3 - 1.5e-93 313.8 0.4 1.5e-93 313.8 0.4 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit zf-C3HC4_3 PF13920.4 112128.5_03724001_2 - 5.5e-10 38.8 10.7 1.6e-09 37.3 10.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 112128.5_03724001_2 - 0.00018 21.1 12.4 0.00055 19.6 12.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Bacillus_HBL PF05791.9 112128.5_03724001_2 - 0.29 10.7 1.2 0.41 10.2 1.2 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Ribosomal_L30_N PF08079.10 202575.1_03723001_1 - 5.5e-28 96.9 14.7 1.1e-27 95.9 14.7 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.18 202575.1_03723001_1 - 1.5e-21 75.9 1.9 1.5e-21 75.9 1.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e RHD3 PF05879.10 202579.1_03726001_2 - 3.1e-11 42.0 0.3 3.9e-11 41.7 0.3 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.21 202579.1_03726001_2 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.21 202579.1_03726001_2 - 0.046 13.7 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.25 202579.1_03726001_2 - 0.17 12.3 0.0 0.27 11.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter RHD3 PF05879.10 202579.1_03726001_3 - 2.9e-301 1001.0 3.4 3.9e-301 1000.5 3.4 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Pepsin-I3 PF06394.11 202579.1_03726001_3 - 4.7 7.3 5.8 1.5 8.9 0.8 2.3 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain PPR_2 PF13041.4 112334.2_03725001_1 - 3.6e-53 177.4 6.8 1.6e-10 40.9 0.0 10.0 7 3 3 10 10 10 8 PPR repeat family PPR PF01535.18 112334.2_03725001_1 - 6.7e-51 166.9 21.2 1e-05 25.3 0.0 13.5 14 0 0 14 14 14 11 PPR repeat PPR_1 PF12854.5 112334.2_03725001_1 - 2.2e-25 87.9 11.7 0.011 15.2 0.0 12.1 11 1 1 12 12 12 8 PPR repeat PPR_3 PF13812.4 112334.2_03725001_1 - 8e-24 83.4 0.0 1.1e-05 25.3 0.0 8.7 8 1 1 9 9 9 6 Pentatricopeptide repeat domain PPR_long PF17177.2 112334.2_03725001_1 - 7.9e-05 22.0 0.0 0.24 10.6 0.0 4.6 4 1 0 5 5 5 1 Pentacotripeptide-repeat region of PROPR DYW_deaminase PF14432.4 112334.2_03725001_1 - 0.0029 17.4 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases RPN7 PF10602.7 112334.2_03725001_1 - 0.18 11.3 0.0 6 6.3 0.0 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 RNase_T PF00929.22 112370.4_03723001_2 - 1.2e-15 58.3 0.0 1.9e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease SPG48 PF14764.4 001338151.1_03724001_1 - 1.5e-34 118.8 1.1 1.5e-34 118.8 1.1 2.4 3 0 0 3 3 3 1 AP-5 complex subunit, vesicle trafficking MBD PF01429.17 001338189.1_03723001_1 - 2.4e-12 46.2 0.0 4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyl-CpG binding domain DEAD PF00270.27 001338264.1_03726001_3 - 3.3e-40 137.6 0.0 1e-39 136.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001338264.1_03726001_3 - 8.1e-28 96.9 1.4 1e-26 93.4 0.2 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain YL1 PF05764.11 001338264.1_03726001_3 - 0.0012 18.9 18.4 0.0012 18.9 18.4 3.9 4 1 0 4 4 4 1 YL1 nuclear protein AAA_22 PF13401.4 001338264.1_03726001_3 - 0.0019 18.4 0.2 0.014 15.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.4 001338264.1_03726001_3 - 0.14 12.2 1.5 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain Hid1 PF12722.5 001338264.1_03726001_3 - 3.5 5.5 11.4 0.28 9.1 5.7 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PPR_2 PF13041.4 112565.2_03725001_3 - 4.4e-107 350.0 19.4 2.1e-18 66.1 0.1 10.8 3 3 8 11 11 11 11 PPR repeat family PPR_1 PF12854.5 112565.2_03725001_3 - 7.3e-85 278.2 9.6 8.5e-15 54.0 0.0 10.8 11 0 0 11 11 11 9 PPR repeat PPR PF01535.18 112565.2_03725001_3 - 3.1e-67 218.1 22.8 1.1e-07 31.5 0.0 12.9 13 0 0 13 13 13 9 PPR repeat PPR_3 PF13812.4 112565.2_03725001_3 - 8e-53 176.3 0.3 6e-11 42.1 0.0 7.7 5 1 4 9 9 9 8 Pentatricopeptide repeat domain PPR_long PF17177.2 112565.2_03725001_3 - 7.5e-37 126.6 0.0 6.7e-17 61.4 0.0 3.7 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PROPR MRP-S27 PF10037.7 112565.2_03725001_3 - 0.00017 20.5 0.3 1.2 7.8 0.0 3.9 3 1 1 5 5 5 2 Mitochondrial 28S ribosomal protein S27 RPM2 PF08579.9 112565.2_03725001_3 - 0.003 17.8 0.0 38 4.5 0.0 5.1 4 1 1 5 5 5 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.4 112565.2_03725001_3 - 0.0067 16.8 0.0 5.5 7.4 0.0 4.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_5 PF12688.5 112565.2_03725001_3 - 0.03 14.4 0.0 0.095 12.8 0.0 1.9 1 0 0 1 1 1 0 Tetratrico peptide repeat DUF3368 PF11848.6 112565.2_03725001_3 - 0.054 13.2 1.3 4.2 7.1 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) Clathrin PF00637.18 112565.2_03725001_3 - 0.1 12.3 0.3 15 5.3 0.0 3.8 3 2 1 4 4 4 0 Region in Clathrin and VPS HECT PF00632.23 112597.4_03729001_1 - 1.6e-91 306.9 0.3 2.7e-91 306.1 0.3 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RING_2 PF13639.4 202607.2_03725001_1 - 1.1e-13 51.1 5.8 2.1e-13 50.1 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 202607.2_03725001_1 - 1.5e-09 37.2 2.9 3.3e-09 36.2 2.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 202607.2_03725001_1 - 4.8e-09 35.8 5.0 9e-09 34.9 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 202607.2_03725001_1 - 6.9e-08 32.5 7.9 2.2e-07 30.9 7.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 202607.2_03725001_1 - 7.7e-06 25.6 3.7 1.4e-05 24.7 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 202607.2_03725001_1 - 0.0019 18.1 1.5 0.0038 17.1 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.4 202607.2_03725001_1 - 0.002 18.0 3.5 0.0045 16.8 3.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 202607.2_03725001_1 - 0.002 17.9 2.5 0.0041 16.9 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 202607.2_03725001_1 - 0.006 16.3 4.2 0.011 15.4 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 202607.2_03725001_1 - 0.015 15.1 2.2 0.032 14.0 2.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.3 202607.2_03725001_1 - 0.051 13.1 4.6 0.095 12.2 4.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.6 202607.2_03725001_1 - 0.054 13.5 3.5 0.17 12.0 3.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain HemY_N PF07219.11 202607.2_03725001_1 - 0.32 11.0 1.2 0.71 9.9 1.2 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Root_cap PF06830.9 112830.3_03724001_3 - 3.1e-29 100.8 0.2 5.3e-29 100.0 0.2 1.4 1 0 0 1 1 1 1 Root cap UCH PF00443.27 113023.4_03724001_2 - 8.6e-49 166.2 0.4 1.1e-48 165.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 113023.4_03724001_2 - 1.1e-09 38.3 2.2 4.1e-09 36.4 2.2 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.21 113023.4_03724001_2 - 5.4e-08 32.3 0.1 1.8e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Peptidase_C98 PF15499.4 113023.4_03724001_2 - 0.00061 19.2 2.1 0.021 14.2 0.1 2.5 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Med6 PF04934.12 113030.5_03722001_1 - 8e-41 138.8 0.0 1.2e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Dala_Dala_lig_C PF07478.11 113030.5_03722001_1 - 0.016 14.6 0.1 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Ribosomal_S5_C PF03719.13 113030.5_03722001_1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain PTR2 PF00854.19 113062.3_03725001_3 - 1.9e-109 366.0 5.0 2.8e-109 365.4 5.0 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.14 113062.3_03725001_3 - 1.2e-08 34.1 30.9 1.7e-08 33.7 25.0 3.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.23 001338584.1_03725001_2 - 7.3e-50 169.6 0.0 1.1e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001338584.1_03725001_2 - 3e-35 121.6 0.0 5.3e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001338584.1_03725001_2 - 0.045 13.5 0.2 0.17 11.7 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Prefoldin_2 PF01920.18 180295.1_03722001_2 - 1.4e-23 82.7 3.4 1.7e-23 82.4 3.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.15 180295.1_03722001_2 - 0.0019 18.0 1.9 0.0077 16.0 1.9 1.8 1 1 0 1 1 1 1 Prefoldin subunit CENP-Q PF13094.4 180295.1_03722001_2 - 0.05 13.6 0.9 0.05 13.6 0.9 1.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2842 PF11003.6 180295.1_03722001_3 - 0.074 13.2 2.3 0.14 12.3 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) zf-FLZ PF04570.12 113154.4_03724001_3 - 4.9e-20 70.7 7.5 1e-19 69.7 7.5 1.5 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 LRR_8 PF13855.4 113201.2_03725001_2 - 7e-46 153.7 58.0 2.6e-08 33.4 2.2 10.6 5 4 3 10 10 10 10 Leucine rich repeat LRR_4 PF12799.5 113201.2_03725001_2 - 9e-32 108.4 60.5 1.4e-05 25.2 0.8 12.3 5 3 9 15 15 15 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 113201.2_03725001_2 - 1.4e-22 76.5 63.8 0.13 12.7 0.0 19.2 19 2 1 20 20 20 9 Leucine Rich Repeat LRR_6 PF13516.4 113201.2_03725001_2 - 1.1e-11 43.6 50.0 0.2 11.7 0.5 15.9 17 0 0 17 17 17 6 Leucine Rich repeat LRR_9 PF14580.4 113201.2_03725001_2 - 0.022 14.1 4.4 1 8.7 0.1 3.6 3 1 1 4 4 4 0 Leucine-rich repeat HSF_DNA-bind PF00447.15 113201.2_03725001_2 - 0.085 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 HSF-type DNA-binding LRRNT_2 PF08263.10 113201.2_03725001_3 - 6.3e-10 39.0 1.7 1.5e-09 37.9 1.7 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain TPX2 PF06886.9 001338614.1_03723001_2 - 1.7e-19 69.6 15.6 1.7e-19 69.6 15.6 2.8 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) RVT_3 PF13456.4 113234.1_03722001_1 - 5.6e-34 116.4 0.1 7.7e-34 115.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like RRM_1 PF00076.20 001338627.1_03726001_1 - 0.00023 20.8 0.0 0.6 9.8 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tox-REase-7 PF15649.4 001338627.1_03726001_1 - 0.12 12.6 0.1 4.5 7.5 0.0 3.0 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 Filamin PF00630.17 113295.3_03728001_2 - 1.5e-17 64.2 0.4 4e-17 62.8 0.4 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat RRM_1 PF00076.20 113295.3_03728001_2 - 9.7e-14 50.8 0.0 1.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 113295.3_03728001_2 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 113295.3_03728001_2 - 0.037 13.8 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.4 113295.3_03728001_2 - 0.067 13.0 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ECH_2 PF16113.3 001084736.2_03724001_3 - 9.8e-107 357.2 0.0 1.2e-106 356.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.18 001084736.2_03724001_3 - 3e-24 85.5 0.0 5.7e-24 84.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RMI1_N PF08585.10 001084736.2_03724001_3 - 0.08 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 RecQ mediated genome instability protein HSF_DNA-bind PF00447.15 113363.2_03724001_3 - 3.2e-28 98.0 0.3 6.2e-28 97.1 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding IFP_35_N PF07334.11 113363.2_03724001_3 - 0.0014 18.5 3.4 0.0014 18.5 3.4 2.0 2 0 0 2 2 2 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus Cauli_DNA-bind PF03310.11 113363.2_03724001_3 - 0.058 13.3 2.5 0.096 12.6 2.5 1.3 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein DivIC PF04977.13 113363.2_03724001_3 - 5 6.8 11.9 0.12 12.0 0.9 2.8 3 0 0 3 3 3 0 Septum formation initiator Pkinase PF00069.23 113453.3_03725001_2 - 5e-43 147.2 0.0 7e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 113453.3_03725001_2 - 2.5e-40 138.3 0.0 3.4e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRRNT_2 PF08263.10 113453.3_03725001_2 - 3e-12 46.5 0.2 7.2e-12 45.3 0.2 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.4 113453.3_03725001_2 - 1.8e-11 43.5 28.9 3.4e-08 33.0 7.1 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 113453.3_03725001_2 - 1.8e-09 37.5 19.5 2.6e-06 27.5 1.6 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 113453.3_03725001_2 - 8.6e-05 22.4 10.5 1 10.0 0.1 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.4 113453.3_03725001_2 - 0.00081 19.1 3.9 2.6 8.2 0.1 4.1 3 0 0 3 3 3 2 Leucine Rich repeat DUF4448 PF14610.4 113453.3_03725001_2 - 0.092 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PAP_fibrillin PF04755.10 113511.6_03723001_2 - 6.3e-42 143.6 1.0 4.8e-40 137.5 1.0 2.2 1 1 0 1 1 1 1 PAP_fibrillin p450 PF00067.20 113527.2_03724001_3 - 2.2e-104 349.7 0.0 2.7e-104 349.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ELF PF03317.11 113527.2_03724001_3 - 0.047 13.1 0.8 0.081 12.3 0.8 1.3 1 0 0 1 1 1 0 ELF protein Chromosome_seg PF13889.4 180306.3_03726001_3 - 5.6e-27 93.5 0.2 1.3e-26 92.4 0.2 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.4 180306.3_03726001_3 - 2.4e-05 24.7 5.9 2.5e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4210) Uroplakin_II PF07353.10 180306.3_03726001_3 - 0.025 13.9 0.3 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 Uroplakin II TRAM_LAG1_CLN8 PF03798.14 113641.4_03723001_3 - 1.5e-17 63.9 8.9 1.5e-17 63.9 8.9 2.0 2 1 0 2 2 2 1 TLC domain DUF971 PF06155.10 001035705.2_03722001_1 - 0.00043 20.7 0.3 0.00062 20.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DUF971 PF06155.10 001035705.2_03722001_3 - 2.8e-10 40.6 0.0 4.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF971) EamA PF00892.18 001338935.1_03723001_1 - 5.5e-08 32.9 21.0 8.8e-05 22.6 5.0 2.6 2 1 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.12 001338935.1_03723001_1 - 0.038 13.0 7.7 0.26 10.2 1.2 2.7 2 1 1 3 3 3 0 Magnesium transporter NIPA Intg_mem_TP0381 PF09529.8 001338935.1_03723001_1 - 0.059 12.7 7.4 0.46 9.8 3.9 2.2 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) RseC_MucC PF04246.10 001338935.1_03723001_1 - 2.2 8.1 7.9 7.5 6.4 0.9 2.4 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ABC_membrane PF00664.21 113754.3_03729001_1 - 2.9e-100 335.3 25.1 8.6e-52 176.3 8.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 113754.3_03729001_1 - 8e-70 233.6 0.1 1e-34 119.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.17 113754.3_03729001_1 - 4e-13 49.2 8.7 0.00018 20.9 0.1 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.4 113754.3_03729001_1 - 8.8e-10 38.0 2.2 0.00021 20.8 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.4 113754.3_03729001_1 - 1.3e-08 35.3 0.3 0.0078 16.5 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.4 113754.3_03729001_1 - 8.8e-08 32.0 0.8 0.0046 16.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.4 113754.3_03729001_1 - 4.5e-07 30.1 3.9 0.013 15.7 0.1 3.9 3 2 0 3 3 3 2 AAA domain DUF258 PF03193.14 113754.3_03729001_1 - 5.5e-07 29.5 0.0 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.10 113754.3_03729001_1 - 5.9e-07 28.9 0.1 0.0032 16.7 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.4 113754.3_03729001_1 - 6.1e-07 29.3 0.1 0.00031 20.4 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.4 113754.3_03729001_1 - 4.5e-06 26.6 1.3 0.08 12.6 0.0 3.7 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.7 113754.3_03729001_1 - 7.4e-06 24.9 2.7 0.032 12.9 0.0 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_23 PF13476.4 113754.3_03729001_1 - 4e-05 24.1 1.5 0.011 16.1 0.8 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.27 113754.3_03729001_1 - 4.5e-05 23.8 1.4 0.15 12.3 0.0 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.4 113754.3_03729001_1 - 0.00061 19.8 4.4 0.8 9.9 0.6 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.4 113754.3_03729001_1 - 0.0025 18.2 0.0 5.7 7.3 0.0 3.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.18 113754.3_03729001_1 - 0.004 16.2 0.0 1.3 7.9 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_24 PF13479.4 113754.3_03729001_1 - 0.0052 16.4 0.1 3.6 7.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain DLIC PF05783.9 113754.3_03729001_1 - 0.006 15.3 0.1 0.22 10.2 0.0 2.2 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) DUF87 PF01935.15 113754.3_03729001_1 - 0.0062 16.5 4.5 1.5 8.7 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_28 PF13521.4 113754.3_03729001_1 - 0.012 15.7 0.1 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.4 113754.3_03729001_1 - 0.019 14.4 0.0 8.2 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.4 113754.3_03729001_1 - 0.022 14.8 0.0 9 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.12 113754.3_03729001_1 - 0.036 13.9 0.5 16 5.4 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.21 113754.3_03729001_1 - 0.041 13.8 0.5 9.4 6.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.4 113754.3_03729001_1 - 0.047 14.0 0.1 7.4 6.9 0.0 3.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.15 113754.3_03729001_1 - 0.05 13.2 0.2 7.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.4 113754.3_03729001_1 - 0.052 13.7 0.6 3.4 7.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.18 113754.3_03729001_1 - 0.062 13.1 0.1 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.15 113754.3_03729001_1 - 0.16 11.6 1.9 61 3.2 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein BPL_LplA_LipB PF03099.17 113822.3_03723001_3 - 0.089 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family SPOC PF07744.11 001084754.2_03722001_1 - 9.8e-05 22.2 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 SPOC domain Transposase_24 PF03004.12 113919.4_03724001_1 - 1.2e-23 83.7 0.0 1.9e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) zf-CCHC PF00098.21 114215.1_03723001_1 - 0.015 15.2 0.9 0.032 14.2 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle CN_hydrolase PF00795.20 114298.3_03724001_3 - 2.5e-74 249.8 0.0 3e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TIR PF01582.18 001339142.1_03729001_2 - 2.7e-55 186.8 0.0 4.2e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain NB-ARC PF00931.20 001339142.1_03729001_2 - 1.1e-23 83.5 0.0 2.5e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TIR_2 PF13676.4 001339142.1_03729001_2 - 3.1e-10 40.2 0.0 6.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001339142.1_03729001_2 - 2.6e-08 33.9 45.4 0.0017 18.5 3.9 7.2 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_3 PF07725.10 001339142.1_03729001_2 - 6.1e-08 32.0 0.2 6.1e-08 32.0 0.2 3.2 4 0 0 4 4 4 1 Leucine Rich Repeat AAA PF00004.27 001339142.1_03729001_2 - 2.8e-05 24.4 0.0 7.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 001339142.1_03729001_2 - 4.2e-05 23.7 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.7 001339142.1_03729001_2 - 6.4e-05 21.9 0.1 0.015 14.1 0.2 2.2 1 1 1 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.4 001339142.1_03729001_2 - 0.00022 21.5 0.0 0.0011 19.3 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain LRR_5 PF13306.4 001339142.1_03729001_2 - 0.00084 19.2 11.0 0.14 12.0 2.8 3.2 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_8 PF13855.4 001339142.1_03729001_2 - 0.0031 17.1 26.0 0.039 13.6 3.1 5.5 4 2 2 7 7 7 3 Leucine rich repeat DUF1863 PF08937.9 001339142.1_03729001_2 - 0.037 14.2 0.1 0.075 13.2 0.1 1.5 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) ABC_tran PF00005.25 001339142.1_03729001_2 - 0.053 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.20 001339142.1_03729001_2 - 0.071 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.4 001339142.1_03729001_2 - 0.08 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.4 001339142.1_03729001_2 - 0.17 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nrap PF03813.12 114445.4_03723001_1 - 0.0022 15.6 0.0 0.0033 15.0 0.0 1.1 1 0 0 1 1 1 1 Nrap protein PAP_central PF04928.15 114445.4_03723001_1 - 0.0034 16.2 0.1 0.0083 15.0 0.1 1.7 1 1 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.21 114445.4_03723001_1 - 0.018 15.2 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Myb_DNA-binding PF00249.29 001035739.2_03723001_1 - 3.1e-21 75.1 3.4 6.6e-16 58.1 1.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001035739.2_03723001_1 - 1.4e-10 41.1 2.4 3.3e-06 27.1 1.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain IQCJ-SCHIP1 PF15157.4 001035739.2_03723001_1 - 0.052 13.3 1.1 0.091 12.5 1.1 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Myb_DNA-binding PF00249.29 001035739.2_03723001_3 - 8.8e-08 32.0 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Malectin_like PF12819.5 114501.2_03726001_1 - 4e-110 368.0 0.2 5.3e-110 367.6 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate-binding protein of the ER Pkinase_Tyr PF07714.15 114501.2_03726001_1 - 8.3e-46 156.2 0.0 1.6e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 114501.2_03726001_1 - 3.5e-43 147.7 0.0 6.7e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.4 114501.2_03726001_1 - 1.1e-07 31.4 5.7 2.3e-07 30.3 5.7 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.5 114501.2_03726001_1 - 1e-05 25.6 8.7 0.0002 21.5 4.8 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) EphA2_TM PF14575.4 114501.2_03726001_1 - 0.1 13.3 0.0 1.8 9.3 0.1 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRR_1 PF00560.31 114501.2_03726001_1 - 0.38 11.3 5.9 5.7 7.7 0.4 4.2 2 1 1 3 3 3 0 Leucine Rich Repeat P12 PF12669.5 114501.2_03726001_1 - 2.4 8.5 3.6 49 4.3 2.1 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family DIOX_N PF14226.4 114517.3_03723001_2 - 7.6e-26 91.1 0.0 1.2e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.18 114517.3_03723001_2 - 1.4e-20 73.5 0.0 2.5e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PPR_2 PF13041.4 001339278.1_03723001_2 - 2.7e-15 56.2 0.0 6.6e-11 42.1 0.1 2.3 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.18 001339278.1_03723001_2 - 1.6e-10 40.4 0.2 0.00022 21.1 0.7 2.5 2 0 0 2 2 2 2 PPR repeat PPR_1 PF12854.5 001339278.1_03723001_2 - 1.6e-08 34.0 0.1 0.00046 19.7 0.0 2.3 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.4 001339278.1_03723001_2 - 6.2e-05 22.9 0.0 0.0028 17.6 0.0 2.0 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.2 001339278.1_03723001_2 - 0.0063 15.8 0.0 0.0091 15.3 0.0 1.1 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PROPR Pollen_allerg_1 PF01357.19 001339299.1_03724001_1 - 0.12 12.3 1.1 0.27 11.2 1.1 1.5 1 0 0 1 1 1 0 Pollen allergen Glyco_hydro_3 PF00933.19 001339299.1_03724001_2 - 3.2e-55 187.6 0.0 4.3e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.20 001339299.1_03724001_2 - 8.2e-35 120.4 0.0 1.1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain zf-C3HC4_3 PF13920.4 114583.5_03724001_2 - 6.6e-08 32.2 8.0 1.1e-07 31.5 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 114583.5_03724001_2 - 5.4e-07 29.6 10.2 1e-06 28.8 10.2 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.4 114583.5_03724001_2 - 1.7e-06 27.7 7.6 2.9e-06 26.9 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.4 114583.5_03724001_2 - 4.5e-06 26.3 9.6 7.8e-06 25.5 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 114583.5_03724001_2 - 9.5e-05 22.1 9.7 0.00018 21.2 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 114583.5_03724001_2 - 0.00022 21.0 7.9 0.00042 20.1 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 114583.5_03724001_2 - 0.0027 17.6 6.2 0.0088 15.9 5.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.5 114583.5_03724001_2 - 0.0068 16.5 5.5 0.015 15.5 5.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain IBR PF01485.19 114583.5_03724001_2 - 0.07 13.2 4.9 0.13 12.4 4.9 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_10 PF16685.3 114583.5_03724001_2 - 0.09 12.8 3.5 0.22 11.5 3.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.4 114583.5_03724001_2 - 0.24 11.0 7.0 0.49 10.0 7.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.5 114583.5_03724001_2 - 0.54 10.2 5.0 7.8 6.5 5.0 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.4 114583.5_03724001_2 - 2.6 8.2 8.2 5.5 7.1 8.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING dCMP_cyt_deam_1 PF00383.21 114712.3_03722001_1 - 2.8e-25 88.0 0.0 4.5e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.4 114712.3_03722001_1 - 3.2e-11 43.0 0.0 4.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.4 114712.3_03722001_1 - 0.0056 16.6 0.2 0.88 9.5 0.1 2.6 2 1 1 3 3 3 2 Bd3614-like deaminase Prion_bPrPp PF11587.6 001084794.1_03722001_1 - 0.26 11.0 0.0 0.26 11.0 0.0 3.1 4 0 0 4 4 4 0 Major prion protein bPrPp - N terminal UPF0160 PF03690.11 114792.3_03723001_2 - 6.2e-129 430.0 0.0 7.2e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF1092 PF06485.9 114792.3_03723001_3 - 0.09 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) Clat_adaptor_s PF01217.18 114946.2_03723001_2 - 8.1e-48 161.8 1.0 1.1e-47 161.5 1.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.4 114946.2_03723001_2 - 0.032 14.1 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 TAXi_N PF14543.4 001339511.1_03724001_3 - 2.7e-34 118.9 2.4 3.4e-34 118.5 0.5 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.21 001339511.1_03724001_3 - 1.9e-17 63.5 2.9 1.4e-16 60.6 2.9 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.4 001339511.1_03724001_3 - 7.1e-17 61.5 0.1 1.1e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TPR_2 PF07719.15 115216.3_03724001_2 - 1.5e-08 34.0 0.1 1 9.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.4 115216.3_03724001_2 - 1.3e-07 31.9 0.1 0.056 13.8 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.4 115216.3_03724001_2 - 3.5e-07 30.3 0.0 1.8 9.4 0.0 4.6 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.4 115216.3_03724001_2 - 8.8e-07 29.4 0.0 0.81 10.3 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.26 115216.3_03724001_2 - 0.00022 20.8 0.2 3.2 7.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.4 115216.3_03724001_2 - 0.00051 20.4 0.1 2.4 8.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.6 115216.3_03724001_2 - 0.0016 17.3 2.1 0.054 12.3 0.0 2.4 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 HrpB1_HrpK PF09613.8 115216.3_03724001_2 - 0.0018 17.8 0.1 0.066 12.7 0.1 2.3 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.4 115216.3_03724001_2 - 0.0057 16.2 0.1 0.12 12.0 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.4 115216.3_03724001_2 - 0.02 15.1 0.0 2.2 8.7 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat YkuI_C PF10388.7 115216.3_03724001_2 - 0.021 14.5 0.2 0.056 13.1 0.2 1.7 1 1 0 1 1 1 0 EAL-domain associated signalling protein domain Fis1_TPR_C PF14853.4 115216.3_03724001_2 - 0.033 14.1 0.3 1.7 8.6 0.0 2.9 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.4 115216.3_03724001_2 - 0.045 12.8 0.1 0.12 11.5 0.0 1.5 1 1 1 2 2 2 0 Tetratricopeptide repeat PPR PF01535.18 115216.3_03724001_2 - 0.14 12.3 2.1 9.9 6.5 0.0 3.5 4 0 0 4 4 3 0 PPR repeat Ras PF00071.20 001084809.2_03723001_1 - 5.6e-65 217.7 0.2 7.3e-65 217.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001084809.2_03723001_1 - 2.2e-34 118.1 0.1 3.8e-34 117.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001084809.2_03723001_1 - 2.2e-14 53.2 0.1 3.2e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001084809.2_03723001_1 - 6.5e-05 22.4 0.1 0.00014 21.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.10 001084809.2_03723001_1 - 0.00017 20.9 0.1 0.00024 20.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001084809.2_03723001_1 - 0.00019 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001084809.2_03723001_1 - 0.0017 18.1 0.9 0.93 9.2 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.4 001084809.2_03723001_1 - 0.14 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bromodomain PF00439.23 115318.3_03725001_2 - 1.9e-22 79.0 0.4 3.3e-22 78.2 0.4 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.23 115318.3_03725001_2 - 2.5e-09 37.3 0.0 5.5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.5 115318.3_03725001_2 - 6.7e-08 32.4 0.2 1.9e-07 30.9 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 115318.3_03725001_2 - 0.0002 21.6 0.2 0.00041 20.6 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SPOB_a PF14689.4 115318.3_03725001_2 - 0.061 12.9 0.7 0.17 11.5 0.7 1.7 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain BES1_N PF05687.11 115318.3_03725001_2 - 6.1 7.1 7.4 1.9e+02 2.3 8.3 2.4 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal Zein-binding PF04576.13 001339690.1_03725001_1 - 1.3e-30 105.3 17.2 2.8e-30 104.3 17.2 1.6 1 0 0 1 1 1 1 Zein-binding Reo_sigmaC PF04582.10 001339690.1_03725001_1 - 0.24 10.6 3.3 0.69 9.1 0.0 2.3 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF5057 PF16480.3 001339690.1_03725001_1 - 0.48 9.6 2.2 0.78 8.9 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5057) GAS PF13851.4 001339690.1_03725001_1 - 0.86 8.8 15.5 0.33 10.2 0.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.13 001339690.1_03725001_1 - 1.1 9.0 12.2 0.46 10.2 8.1 2.0 2 0 0 2 2 2 0 Mnd1 family TMF_DNA_bd PF12329.6 001339690.1_03725001_1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.14 001339690.1_03725001_1 - 1.4 9.3 8.5 0.59 10.5 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 CENP-H PF05837.10 001339690.1_03725001_1 - 1.5 9.2 12.4 1.4 9.2 7.6 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.9 001339690.1_03725001_1 - 2.1 7.0 15.6 0.7 8.6 10.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Ras PF00071.20 001084818.1_03723001_3 - 9.9e-57 190.9 0.0 1.3e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001084818.1_03723001_3 - 1.9e-34 118.3 0.0 2.6e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001084818.1_03723001_3 - 1.3e-09 37.6 0.0 1.7e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001084818.1_03723001_3 - 1.3e-05 24.5 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.14 001084818.1_03723001_3 - 0.00011 22.1 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001084818.1_03723001_3 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Kinesin PF00225.21 001339703.1_03728001_2 - 3.3e-97 325.3 0.4 3.3e-97 325.3 0.4 2.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.3 001339703.1_03728001_2 - 5.4e-20 71.7 0.0 5.4e-20 71.7 0.0 3.0 2 1 1 3 3 3 1 Microtubule binding Arm PF00514.21 001339703.1_03728001_2 - 4.1e-17 61.5 2.5 1.4e-05 24.8 0.2 4.6 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Filament PF00038.19 001339703.1_03728001_2 - 0.013 15.0 63.1 0.011 15.2 31.0 3.6 1 1 1 3 3 3 0 Intermediate filament protein HEAT_2 PF13646.4 001339703.1_03728001_2 - 0.051 13.8 1.9 2 8.7 0.6 3.4 2 1 1 3 3 3 0 HEAT repeats Glyco_hydro_98C PF08307.9 001339703.1_03728001_2 - 0.084 12.2 5.6 0.26 10.6 5.6 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain TPR_MLP1_2 PF07926.10 001339703.1_03728001_2 - 5.1 7.0 70.0 0.27 11.2 18.3 5.2 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein RRM_1 PF00076.20 115392.4_03725001_1 - 3.9e-27 93.7 0.0 3.7e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.21 115392.4_03725001_1 - 1.1e-14 53.6 18.0 0.00015 21.6 0.6 3.6 3 0 0 3 3 3 3 Zinc knuckle RRM_7 PF16367.3 115392.4_03725001_1 - 4.1e-06 26.7 0.0 0.025 14.5 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.4 115392.4_03725001_1 - 0.0033 17.2 0.0 0.0089 15.8 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CpXC PF14353.4 115392.4_03725001_1 - 0.0088 15.9 4.5 1.6 8.6 0.0 3.8 4 0 0 4 4 4 1 CpXC protein Laminin_G_1 PF00054.21 115392.4_03725001_1 - 0.081 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain zf-CCHC_3 PF13917.4 115392.4_03725001_1 - 0.27 11.1 16.5 4 7.3 0.5 3.4 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.4 115392.4_03725001_1 - 3.4 7.3 15.3 7.1 6.3 0.3 4.2 4 0 0 4 4 4 0 Zinc knuckle FKBP_C PF00254.26 115409.3_03723001_3 - 6.9e-26 90.3 0.0 1.1e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Mur_ligase_M PF08245.10 180686.2_03724001_3 - 1.7e-08 34.6 0.0 2e-07 31.1 0.0 2.2 1 1 1 2 2 2 1 Mur ligase middle domain SmpA_OmlA PF04355.11 001035788.3_03723001_3 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 SmpA / OmlA family FBD PF08387.8 115425.1_03722001_1 - 2.6e-37 126.3 0.3 2.3e-18 65.7 0.1 2.4 2 0 0 2 2 2 2 FBD Read-through PF16814.3 115425.1_03722001_1 - 0.067 12.9 0.0 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Read-through domain GRP PF07172.9 115437.2_03721001_1 - 9e-06 26.2 2.9 1.8e-05 25.2 2.9 1.4 1 0 0 1 1 1 1 Glycine rich protein family Pkinase_Tyr PF07714.15 115463.4_03725001_2 - 3.7e-24 85.3 0.0 1.2e-23 83.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 115463.4_03725001_2 - 2.8e-19 69.4 0.0 4.9e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cys_Met_Meta_PP PF01053.18 115564.4_03724001_1 - 1.8e-147 490.7 0.0 2.2e-147 490.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.17 115564.4_03724001_1 - 3.4e-07 29.4 0.1 8.4e-07 28.1 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V GDC-P PF02347.14 115564.4_03724001_1 - 0.0033 16.2 0.1 0.0051 15.6 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.15 115564.4_03724001_1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glycos_transf_4 PF00953.19 115582.3_03724001_2 - 6.2e-34 117.1 13.0 6.2e-34 117.1 13.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 4 Pox_A14 PF05767.10 115582.3_03724001_2 - 0.0088 16.0 1.6 0.0088 16.0 1.6 2.2 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 AC_N PF16214.3 115582.3_03724001_2 - 0.23 10.4 5.3 0.2 10.6 1.0 2.2 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Metallophos PF00149.26 115712.4_03724001_1 - 6.1e-35 121.4 0.3 8.3e-35 121.0 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.3 115712.4_03724001_1 - 0.00025 21.3 0.5 0.00048 20.4 0.5 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TAXi_N PF14543.4 001035814.1_03724001_3 - 3.1e-38 131.7 9.7 8.7e-28 97.6 2.6 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.4 001035814.1_03724001_3 - 1.5e-33 115.7 0.0 2.8e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.21 001035814.1_03724001_3 - 7.4e-15 55.0 0.3 1.3e-13 50.9 0.3 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF2054 PF10218.7 202731.3_03723001_3 - 5.3e-34 117.0 19.0 5.3e-34 117.0 19.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2054) Glyco_transf_18 PF15024.4 202731.3_03723001_3 - 8.1e-06 24.6 8.9 8.9e-06 24.4 8.9 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 GRAS PF03514.12 115927.5_03725001_3 - 1.3e-100 336.9 0.0 1.6e-100 336.6 0.0 1.1 1 0 0 1 1 1 1 GRAS domain family NYN PF01936.16 115958.3_03723001_3 - 3e-23 82.8 0.0 4.1e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 NYN domain DUF793 PF05633.9 116015.5_03722001_1 - 0.00014 20.9 2.5 0.0067 15.3 0.1 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF793) DUF241 PF03087.12 116015.5_03722001_1 - 0.00016 21.5 1.8 0.081 12.6 0.1 2.2 2 0 0 2 2 2 2 Arabidopsis protein of unknown function Tektin PF03148.12 116015.5_03722001_1 - 0.051 12.2 0.5 0.52 8.9 0.0 2.0 2 0 0 2 2 2 0 Tektin family Lipoprotein_20 PF13942.4 116015.5_03722001_1 - 0.094 12.5 0.1 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 YfhG lipoprotein DUF677 PF05055.10 116015.5_03722001_1 - 0.16 10.7 1.4 3.6 6.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF677) GED PF02212.16 001340127.1_03725001_1 - 2.6e-22 78.6 0.1 4.2e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_M PF01031.18 001340127.1_03725001_1 - 0.015 14.4 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Dynamin central region Dynamin_M PF01031.18 001340127.1_03725001_3 - 1.2e-57 195.2 0.0 2.1e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.21 001340127.1_03725001_3 - 2.3e-51 174.1 0.1 3.4e-51 173.5 0.1 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.21 001340127.1_03725001_3 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_membrane PF00664.21 001340142.1_03729001_1 - 8.8e-116 386.2 33.3 6.3e-59 199.7 10.3 2.4 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001340142.1_03729001_1 - 3.7e-72 241.1 1.5 6e-35 120.6 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.17 001340142.1_03729001_1 - 1.8e-11 43.8 10.1 0.00073 18.9 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.4 001340142.1_03729001_1 - 7.8e-10 38.2 0.2 0.0018 17.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.4 001340142.1_03729001_1 - 9.4e-10 39.0 0.7 0.00058 20.1 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.4 001340142.1_03729001_1 - 2.5e-09 37.4 1.7 0.0016 18.6 0.1 3.3 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.10 001340142.1_03729001_1 - 2e-07 30.4 2.4 0.0041 16.3 0.0 3.4 4 0 0 4 4 4 2 Zeta toxin DUF258 PF03193.14 001340142.1_03729001_1 - 2e-07 30.9 0.1 0.027 14.3 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.7 001340142.1_03729001_1 - 3e-06 26.2 1.5 0.0018 17.0 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class G-alpha PF00503.18 001340142.1_03729001_1 - 3.4e-06 26.3 0.3 0.029 13.4 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit DEAD PF00270.27 001340142.1_03729001_1 - 1.1e-05 25.2 2.5 0.097 12.3 0.2 2.7 2 1 0 2 2 2 2 DEAD/DEAH box helicase AAA_15 PF13175.4 001340142.1_03729001_1 - 4.7e-05 23.1 6.5 0.15 11.5 0.0 3.4 4 0 0 4 4 3 2 AAA ATPase domain AAA_30 PF13604.4 001340142.1_03729001_1 - 9.3e-05 22.1 4.3 0.13 11.9 0.2 3.5 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.4 001340142.1_03729001_1 - 0.00011 22.0 0.4 0.73 9.4 0.0 3.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.12 001340142.1_03729001_1 - 0.00021 21.2 1.6 0.73 9.7 0.1 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) APS_kinase PF01583.18 001340142.1_03729001_1 - 0.00033 20.4 0.2 1.1 9.0 0.0 2.9 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_24 PF13479.4 001340142.1_03729001_1 - 0.00043 19.9 0.0 0.36 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.4 001340142.1_03729001_1 - 0.00065 19.2 1.3 1.4 8.3 0.0 3.5 4 0 0 4 4 4 2 AAA domain DUF815 PF05673.11 001340142.1_03729001_1 - 0.0015 17.6 0.1 0.55 9.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PRK PF00485.16 001340142.1_03729001_1 - 0.0045 16.6 0.5 3.1 7.3 0.0 2.7 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.21 001340142.1_03729001_1 - 0.005 16.8 0.0 5 7.1 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase KAP_NTPase PF07693.12 001340142.1_03729001_1 - 0.0074 15.4 0.0 2.6 7.1 0.0 2.7 2 1 0 2 2 2 1 KAP family P-loop domain Dynamin_N PF00350.21 001340142.1_03729001_1 - 0.0094 15.9 0.9 11 5.9 0.0 3.6 3 0 0 3 3 3 0 Dynamin family NACHT PF05729.10 001340142.1_03729001_1 - 0.011 15.5 0.8 7.5 6.3 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.4 001340142.1_03729001_1 - 0.012 16.0 0.0 8.5 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.15 001340142.1_03729001_1 - 0.017 15.0 7.0 1 9.2 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function DUF87 SbcCD_C PF13558.4 001340142.1_03729001_1 - 0.021 14.9 10.7 0.86 9.8 0.8 4.4 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Roc PF08477.11 001340142.1_03729001_1 - 0.032 14.3 0.1 9.6 6.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.4 001340142.1_03729001_1 - 0.033 14.2 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.24 001340142.1_03729001_1 - 0.036 13.6 0.0 6 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DLIC PF05783.9 001340142.1_03729001_1 - 0.049 12.3 0.1 0.89 8.2 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) FERM_N PF09379.8 001340142.1_03729001_1 - 0.094 12.5 0.8 56 3.6 0.0 3.8 4 0 0 4 4 4 0 FERM N-terminal domain RNA_helicase PF00910.20 001340142.1_03729001_1 - 0.14 12.4 0.0 26 5.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MoaE PF02391.15 001340142.1_03729001_1 - 0.35 11.0 2.3 13 6.0 0.2 2.7 2 0 0 2 2 2 0 MoaE protein NTPase_1 PF03266.13 001340142.1_03729001_1 - 1.2 8.9 7.8 3.8 7.3 0.0 3.7 4 0 0 4 4 4 0 NTPase Ribosomal_L7Ae PF01248.24 116152.3_03723001_2 - 8.3e-25 86.2 0.6 1.5e-24 85.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.10 116152.3_03723001_2 - 0.048 12.6 0.5 0.078 11.9 0.5 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) peroxidase PF00141.21 140823.1_03721120_2 - 0.03 13.9 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Peroxidase eIF3_p135 PF12807.5 143801.1_03722120_3 - 0.039 13.8 0.2 0.05 13.5 0.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF596 PF04591.10 141002.1_03721120_3 - 0.16 12.0 0.8 1.1 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF596 DUF1985 PF09331.9 141637.1_03723120_3 - 0.00037 20.4 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1985) CpeT PF06206.9 143844.1_03721120_3 - 0.045 13.6 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) DUF295 PF03478.16 141282.1_03721120_3 - 5.2e-09 35.7 0.0 7.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF295) Atracotoxin PF05353.9 141442.1_03721120_1 - 0.018 14.9 0.5 0.032 14.1 0.5 1.5 1 1 0 1 1 1 0 Delta Atracotoxin DUF577 PF04510.10 001341109.1_03724001_1 - 1.2e-135 448.5 14.3 5.2e-72 241.2 2.4 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF577) BAR_3 PF16746.3 001341109.1_03724001_1 - 0.012 15.2 7.9 0.031 13.8 0.3 3.1 3 1 0 3 3 3 0 BAR domain of APPL family WSD PF15613.4 001340802.1_03728001_3 - 3.4e-12 46.6 1.4 4.5e-11 43.0 1.4 2.7 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.15 001340802.1_03728001_3 - 2.6e-10 40.3 1.6 2e-09 37.5 1.5 2.4 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.4 001340802.1_03728001_3 - 5.2e-10 38.5 0.0 3.1e-08 32.8 0.0 2.7 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Homeobox PF00046.27 001340802.1_03728001_3 - 8.1e-10 38.2 0.0 1.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.6 001340802.1_03728001_3 - 0.052 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Response_reg PF00072.22 117704.6_03726001_3 - 1.3e-22 79.9 0.8 2.2e-22 79.2 0.3 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Myb_DNA-binding PF00249.29 117704.6_03726001_3 - 0.00061 19.8 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DNA_pol_phi PF04931.11 117704.6_03726001_3 - 0.14 10.2 2.4 0.19 9.7 2.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.23 001340288.1_03723001_1 - 5.3e-46 157.0 0.0 8.1e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001340288.1_03723001_1 - 9.6e-44 149.5 0.0 1.9e-43 148.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3403 PF11883.6 001340288.1_03723001_1 - 0.0005 20.0 0.3 0.0011 18.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3403) TMEM100 PF16311.3 001340288.1_03723001_1 - 0.038 13.4 0.1 0.097 12.1 0.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 APH PF01636.21 001340288.1_03723001_1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.29 001036490.2_03722001_2 - 1.1e-07 31.7 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain PC-Esterase PF13839.4 116338.4_03724001_2 - 1.2e-88 297.4 0.1 1.5e-88 297.1 0.1 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.4 116338.4_03724001_2 - 2e-21 75.9 2.2 5.6e-21 74.5 2.2 1.8 1 0 0 1 1 1 1 PMR5 N terminal Domain EamA PF00892.18 001340313.1_03724001_1 - 1.6e-08 34.7 22.1 1.7e-08 34.6 15.8 2.4 2 0 0 2 2 2 1 EamA-like transporter family DUF3980 PF13140.4 001340313.1_03724001_1 - 0.065 13.6 2.4 16 5.9 1.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3980) DUF2371 PF10177.7 001340313.1_03724001_1 - 0.11 12.5 0.1 3.8 7.5 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) DUF202 PF02656.13 001340313.1_03724001_1 - 0.38 11.1 4.2 19 5.6 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) EamA PF00892.18 001340313.1_03724001_2 - 7.5e-11 42.2 13.4 1.4e-10 41.4 13.4 1.4 1 0 0 1 1 1 1 EamA-like transporter family Myb_DNA-binding PF00249.29 001125441.1_03723001_3 - 4.8e-32 109.7 1.1 5.9e-16 58.2 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001125441.1_03723001_3 - 4.1e-19 68.4 0.4 1.4e-12 47.6 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.8 001125441.1_03723001_3 - 0.018 14.9 0.0 0.27 11.1 0.0 2.3 1 1 1 2 2 2 0 SLIDE F-box-like PF12937.5 001340397.1_03723001_1 - 2.9e-07 30.1 0.1 6.3e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001340397.1_03723001_1 - 0.0006 19.5 0.3 0.0014 18.3 0.3 1.6 1 0 0 1 1 1 1 F-box domain FTHFS PF01268.17 116543.6_03727001_3 - 0.0073 14.4 0.0 0.011 13.8 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Coprogen_oxidas PF01218.16 116557.4_03723001_3 - 1.3e-120 401.5 0.0 1.6e-120 401.2 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Pectinesterase PF01095.17 116631.4_03724001_1 - 5.5e-134 445.4 1.0 6.9e-134 445.1 1.0 1.1 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.13 116631.4_03724001_1 - 7.9e-08 32.7 0.0 1.8e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor WRKY PF03106.13 116683.3_03725001_2 - 1.1e-26 92.8 3.0 2.4e-26 91.7 3.0 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain Rootletin PF15035.4 116683.3_03725001_2 - 0.03 14.3 10.8 0.051 13.5 10.8 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.10 116683.3_03725001_2 - 0.19 12.0 5.0 0.49 10.7 5.0 1.8 1 0 0 1 1 1 0 Cell division protein ZapB IncA PF04156.12 116683.3_03725001_2 - 0.79 9.3 7.6 0.65 9.6 6.0 1.6 1 1 0 1 1 1 0 IncA protein TYW3 PF02676.12 116705.5_03727001_2 - 2.1e-64 216.7 0.0 3.3e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.14 116705.5_03727001_2 - 2.7e-34 118.5 0.0 4.6e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_4 PF13418.4 116705.5_03727001_2 - 2e-31 107.5 8.4 4.8e-08 32.7 0.1 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.4 116705.5_03727001_2 - 7.5e-27 92.9 0.2 3.3e-06 27.1 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.4 116705.5_03727001_2 - 2.1e-26 91.1 6.1 2.3e-06 27.5 0.0 6.7 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.4 116705.5_03727001_2 - 3.3e-22 77.9 7.3 1.3e-05 24.9 0.2 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.23 116705.5_03727001_2 - 1.2e-21 75.9 8.5 2.6e-07 30.0 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.13 116705.5_03727001_2 - 1.9e-16 59.1 10.7 2.2e-06 27.2 0.0 6.2 6 0 0 6 6 6 3 Kelch motif MTS PF05175.12 116705.5_03727001_2 - 0.00061 19.2 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DNA_methylase PF00145.15 116705.5_03727001_2 - 0.0029 16.9 0.0 0.0062 15.8 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.13 116705.5_03727001_2 - 0.011 15.3 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ank_2 PF12796.5 001203750.2_03726001_3 - 2.1e-31 108.2 7.0 9.7e-11 42.0 0.2 5.2 1 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001203750.2_03726001_3 - 3.7e-22 77.9 9.0 0.046 14.0 0.0 8.6 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.4 001203750.2_03726001_3 - 2.5e-21 73.4 5.5 0.12 12.9 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.4 001203750.2_03726001_3 - 6.4e-20 71.1 5.0 0.0037 17.7 0.0 7.0 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.28 001203750.2_03726001_3 - 2.3e-18 65.6 7.8 0.066 13.6 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat PGG PF13962.4 001203750.2_03726001_3 - 3.3e-18 65.4 2.3 3.3e-18 65.4 2.3 2.2 2 0 0 2 2 2 1 Domain of unknown function Fer2 PF00111.25 116784.4_03723001_2 - 8.3e-13 48.0 0.3 1.2e-12 47.4 0.3 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1644 PF07800.10 116915.6_03724001_3 - 1.1e-58 197.9 12.5 1.1e-34 119.8 1.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1644) HMG_box PF00505.17 116915.6_03724001_3 - 0.059 13.7 1.3 0.17 12.2 0.1 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box zf-Di19 PF05605.10 116915.6_03724001_3 - 0.08 13.1 3.2 53 4.1 0.0 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_2 PF13639.4 116915.6_03724001_3 - 0.62 10.2 7.9 13 6.0 7.9 2.7 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.4 116915.6_03724001_3 - 8.6 6.2 10.5 3.8e+02 0.9 10.5 2.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2752 PF10825.6 001340593.1_03723001_2 - 0.054 13.4 0.4 0.25 11.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zf-RING_2 PF13639.4 117024.4_03725001_1 - 2.8e-12 46.5 9.0 2.8e-12 46.5 9.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.3 117024.4_03725001_1 - 8.8e-10 38.0 7.7 2.3e-09 36.7 7.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.20 117024.4_03725001_1 - 5.2e-07 29.6 0.1 9.3e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.23 117024.4_03725001_1 - 1.3e-06 28.1 8.0 2.8e-06 27.0 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 117024.4_03725001_1 - 6e-06 26.3 8.0 1.3e-05 25.2 8.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.4 117024.4_03725001_1 - 9e-06 25.3 8.9 2e-05 24.2 8.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 117024.4_03725001_1 - 0.00027 20.7 7.4 0.00059 19.6 7.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 117024.4_03725001_1 - 0.0024 17.7 2.7 0.0024 17.7 2.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.5 117024.4_03725001_1 - 0.0033 17.3 3.7 0.0072 16.2 3.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.4 117024.4_03725001_1 - 0.0068 16.1 6.6 0.014 15.1 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 117024.4_03725001_1 - 0.012 15.3 7.0 0.027 14.2 7.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.27 117024.4_03725001_1 - 0.88 9.4 7.4 1.6 8.5 7.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.4 117024.4_03725001_1 - 1.3 8.7 7.1 3.5 7.3 7.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ribosomal_L6 PF00347.21 001340670.1_03723001_3 - 2.1e-21 76.2 2.2 8e-10 39.1 0.2 2.9 3 1 0 3 3 3 2 Ribosomal protein L6 PC4 PF02229.14 117160.4_03722001_2 - 4.2e-24 83.8 0.6 8e-24 82.9 0.6 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DEK_C PF08766.9 117160.4_03722001_2 - 8.8e-14 51.0 4.7 1.5e-13 50.3 4.7 1.4 1 0 0 1 1 1 1 DEK C terminal domain Lsr2 PF11774.6 117160.4_03722001_2 - 0.11 12.5 0.7 0.23 11.5 0.7 1.5 1 1 0 1 1 1 0 Lsr2 MIS13 PF08202.9 117160.4_03722001_2 - 0.19 10.9 7.7 0.26 10.4 7.7 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family PP2C_C PF07830.11 117160.4_03722001_2 - 1.2 9.4 4.2 1.2 9.4 2.8 1.7 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Ribosomal_L31e PF01198.17 001340719.1_03722001_1 - 0.0019 18.3 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e Kelch_1 PF01344.23 117246.1_03723001_1 - 2.1e-21 75.1 7.3 3.1e-10 39.3 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.4 117246.1_03723001_1 - 1.1e-17 63.5 2.6 5.7e-08 32.6 0.1 3.5 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.13 117246.1_03723001_1 - 2.4e-11 43.0 0.9 7e-07 28.9 0.1 4.5 6 0 0 6 6 6 2 Kelch motif F-box PF00646.31 117246.1_03723001_1 - 4.9e-08 32.5 0.2 1.2e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 117246.1_03723001_1 - 5e-05 23.0 0.1 0.00016 21.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like Kelch_4 PF13418.4 117246.1_03723001_1 - 0.00024 20.9 0.1 0.017 15.0 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.4 117246.1_03723001_1 - 0.00075 19.3 3.8 0.0064 16.3 0.2 3.3 3 0 0 3 3 3 1 Kelch motif cIII PF08134.9 117246.1_03723001_1 - 0.066 12.9 0.2 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 cIII protein family Kelch_3 PF13415.4 117246.1_03723001_1 - 0.1 12.8 0.3 30 4.9 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain YTH PF04146.13 001340756.1_03723001_2 - 4e-45 152.3 0.0 5.7e-45 151.8 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain adh_short PF00106.23 001203787.1_03724001_3 - 4.2e-33 114.3 0.1 3.9e-31 107.9 0.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001203787.1_03724001_3 - 3.6e-23 82.2 0.0 1e-21 77.5 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001203787.1_03724001_3 - 1.5e-05 24.8 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 KR domain TrbC PF04956.11 001203787.1_03724001_3 - 0.038 14.1 0.5 0.077 13.1 0.5 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family PGG PF13962.4 202811.4_03722001_3 - 2.3e-14 53.0 8.8 2.3e-14 53.0 8.8 2.3 2 1 0 2 2 2 1 Domain of unknown function RALF PF05498.9 117476.5_03722001_1 - 1e-21 77.4 3.0 1.5e-21 76.8 3.0 1.3 1 0 0 1 1 1 1 Rapid ALkalinization Factor (RALF) PDDEXK_6 PF04720.10 117544.4_03724001_2 - 4.1e-72 242.3 0.4 5.6e-72 241.9 0.4 1.2 1 0 0 1 1 1 1 PDDEXK-like family of unknown function SHS2_Rpb7-N PF03876.15 001340953.1_03722001_1 - 6.4e-08 32.7 0.0 3.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.10 001340953.1_03722001_1 - 0.0031 17.6 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.21 001340953.1_03722001_1 - 0.043 14.0 3.2 0.34 11.2 2.9 2.4 2 1 0 2 2 2 0 S1 RNA binding domain ABC2_membrane PF01061.22 001341002.1_03729001_1 - 3.5e-87 291.1 47.0 6.2e-54 182.5 22.6 3.2 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.25 001341002.1_03729001_1 - 6.6e-39 133.4 0.0 2.2e-20 73.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_assoc PF08370.9 001341002.1_03729001_1 - 8.8e-20 70.0 0.3 8.8e-20 70.0 0.3 2.4 3 0 0 3 3 1 1 Plant PDR ABC transporter associated AAA_21 PF13304.4 001341002.1_03729001_1 - 5.2e-11 42.8 0.0 0.0015 18.3 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_trans_N PF14510.4 001341002.1_03729001_1 - 2.4e-08 34.3 0.0 5.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.5 001341002.1_03729001_1 - 6.4e-08 32.0 47.3 3.7e-05 22.9 24.4 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.4 001341002.1_03729001_1 - 2.2e-07 31.3 0.1 0.0012 19.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.4 001341002.1_03729001_1 - 4e-07 30.5 0.0 0.0016 18.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.14 001341002.1_03729001_1 - 5.9e-07 29.4 1.6 0.0055 16.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.4 001341002.1_03729001_1 - 1.4e-05 24.6 4.3 0.029 13.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.4 001341002.1_03729001_1 - 2e-05 25.1 0.5 0.024 15.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.17 001341002.1_03729001_1 - 3.3e-05 23.3 0.1 0.68 9.2 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain PDR_CDR PF06422.10 001341002.1_03729001_1 - 5e-05 23.0 1.0 0.069 12.9 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter AAA PF00004.27 001341002.1_03729001_1 - 6.9e-05 23.2 1.1 0.0038 17.5 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.4 001341002.1_03729001_1 - 0.0004 19.9 6.3 0.018 14.5 0.2 2.8 3 0 0 3 3 2 2 AAA domain NACHT PF05729.10 001341002.1_03729001_1 - 0.00049 19.9 1.5 0.027 14.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.4 001341002.1_03729001_1 - 0.00058 20.0 2.3 0.055 13.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.4 001341002.1_03729001_1 - 0.00095 19.3 2.7 0.062 13.4 0.2 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.13 001341002.1_03729001_1 - 0.0011 17.9 0.2 0.006 15.4 0.1 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.7 001341002.1_03729001_1 - 0.0013 18.3 2.3 0.12 11.9 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.21 001341002.1_03729001_1 - 0.0057 16.6 1.0 1.2 9.1 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.4 001341002.1_03729001_1 - 0.0059 16.2 2.9 0.31 10.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.12 001341002.1_03729001_1 - 0.0064 16.4 2.9 0.016 15.1 0.2 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.13 001341002.1_03729001_1 - 0.015 15.1 5.9 0.1 12.4 0.1 3.3 3 0 0 3 3 3 0 NTPase AAA_17 PF13207.4 001341002.1_03729001_1 - 0.017 15.4 0.3 0.72 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.17 001341002.1_03729001_1 - 0.022 14.2 4.4 1.1 8.7 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.4 001341002.1_03729001_1 - 0.031 13.8 0.0 1.6 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.20 001341002.1_03729001_1 - 0.034 14.4 0.2 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.4 001341002.1_03729001_1 - 0.065 13.3 6.5 0.82 9.7 0.5 2.7 3 0 0 3 3 2 0 AAA domain ArsR PF09824.7 001341002.1_03729001_1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator AAA_24 PF13479.4 001341002.1_03729001_1 - 0.092 12.3 1.3 5.1 6.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain FeoB_N PF02421.16 001341002.1_03729001_1 - 0.12 11.8 0.2 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_11 PF13086.4 001341002.1_03729001_1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.10 001341002.1_03729001_1 - 0.2 10.8 0.7 0.49 9.5 0.1 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.10 001341002.1_03729001_1 - 0.23 10.6 0.4 4.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.4 001341002.1_03729001_1 - 0.32 11.2 3.1 0.47 10.6 0.1 2.6 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.19 001341002.1_03729001_1 - 0.39 9.9 3.1 0.54 9.5 0.2 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.16 001341002.1_03729001_1 - 0.46 10.0 3.4 1.1 8.8 0.4 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.15 001341002.1_03729001_1 - 0.52 10.2 3.2 4.2 7.2 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FixP_N PF14715.4 001341002.1_03729001_1 - 9.8 5.9 10.1 1.7 8.4 1.8 3.1 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP PMD PF10536.7 117698.2_03725001_3 - 3.3e-105 352.1 0.2 5.7e-105 351.3 0.2 1.4 1 0 0 1 1 1 1 Plant mobile domain DUF912 PF06024.10 117698.2_03725001_3 - 4.1 7.6 13.8 0.091 12.9 1.5 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BUD22 PF09073.8 117698.2_03725001_3 - 4.2 6.5 31.6 6.2 5.9 31.6 1.2 1 0 0 1 1 1 0 BUD22 AKNA PF12443.6 117698.2_03725001_3 - 6.8 7.3 9.3 0.29 11.7 1.0 2.6 3 0 0 3 3 3 0 AT-hook-containing transcription factor 2OG-FeII_Oxy PF03171.18 001203811.1_03723001_1 - 1.6e-24 86.2 0.0 3.2e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001203811.1_03723001_1 - 3e-20 73.0 0.0 4.8e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_S41 PF03572.16 117883.2_03724001_1 - 6e-50 168.9 0.0 8.8e-50 168.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ PF00595.22 117883.2_03724001_1 - 3.1e-08 33.7 0.0 5.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 117883.2_03724001_1 - 1.6e-07 31.4 0.0 5.1e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Tricorn_C1 PF14684.4 117883.2_03724001_1 - 0.096 12.7 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Tricorn protease C1 domain Response_reg PF00072.22 001203830.1_03725001_2 - 8.9e-09 35.4 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Myb_DNA-binding PF00249.29 001203830.1_03725001_2 - 6.7e-08 32.4 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain TIR PF01582.18 118072.4_03729001_1 - 3.5e-57 192.9 7.4 3.4e-35 121.3 1.5 2.3 2 0 0 2 2 2 2 TIR domain NB-ARC PF00931.20 118072.4_03729001_1 - 3.4e-21 75.4 0.0 7.6e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain LRR_4 PF12799.5 118072.4_03729001_1 - 4.1e-20 71.3 32.4 0.0074 16.5 0.3 11.3 7 2 4 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 118072.4_03729001_1 - 1.3e-16 60.0 19.1 0.017 14.7 1.3 8.3 7 2 3 10 10 10 7 Leucine rich repeat TIR_2 PF13676.4 118072.4_03729001_1 - 1.2e-15 57.6 0.3 8e-08 32.4 0.1 3.1 3 0 0 3 3 3 2 TIR domain LRR_3 PF07725.10 118072.4_03729001_1 - 8e-09 34.8 0.5 8e-09 34.8 0.5 3.4 3 0 0 3 3 3 1 Leucine Rich Repeat AAA_16 PF13191.4 118072.4_03729001_1 - 0.0012 19.2 0.0 0.0039 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain FNIP PF05725.10 118072.4_03729001_1 - 0.018 15.1 2.8 57 3.9 0.1 5.1 4 0 0 4 4 4 0 FNIP Repeat AAA_24 PF13479.4 118072.4_03729001_1 - 0.044 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.4 118072.4_03729001_1 - 0.049 13.8 0.1 0.35 11.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain NACHT PF05729.10 118072.4_03729001_1 - 0.11 12.3 0.4 0.33 10.7 0.4 1.9 1 1 0 1 1 1 0 NACHT domain DUF1204 PF06721.9 118171.2_03723001_1 - 3.4e-83 278.4 20.7 3.7e-55 186.7 11.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1204) RVT_1 PF00078.25 118171.2_03723001_1 - 7e-10 38.7 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3450 PF11932.6 118171.2_03723001_1 - 0.0035 16.6 5.2 0.0055 15.9 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.6 118171.2_03723001_1 - 0.26 11.4 8.4 0.082 13.0 4.5 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GrpE PF01025.17 118171.2_03723001_1 - 1.5 8.4 7.4 2.7 7.5 7.4 1.3 1 0 0 1 1 1 0 GrpE Gal-bind_lectin PF00337.20 118224.2_03725001_1 - 1.5e-52 176.5 0.0 2.6e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 Galactoside-binding lectin Galactosyl_T PF01762.19 118224.2_03725001_1 - 4.7e-34 117.8 0.0 1.2e-33 116.4 0.0 1.7 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.14 118224.2_03725001_1 - 0.00031 20.1 0.0 0.00073 18.9 0.0 1.5 2 0 0 2 2 2 1 Fringe-like Sec63 PF02889.14 118237.4_03725001_2 - 2.3e-25 89.1 0.3 5.7e-25 87.8 0.3 1.6 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.29 118237.4_03725001_2 - 1.9e-19 69.4 0.0 5e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain ECF_trnsprt PF12822.5 118237.4_03725001_2 - 0.004 17.1 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 ECF transporter, substrate-specific component Sporozoite_P67 PF05642.9 118237.4_03725001_2 - 3.5 5.5 7.3 5.2 4.9 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Lar_restr_allev PF14354.4 001084963.1_03723001_1 - 0.022 15.0 0.1 0.049 13.9 0.1 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.4 001084963.1_03723001_1 - 0.024 14.2 6.1 1 9.0 1.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-tcix PF14952.4 001084963.1_03723001_1 - 2.1 7.9 7.8 3.5 7.2 1.7 2.5 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Ferlin_C PF16165.3 001084963.1_03723001_3 - 0.24 11.2 2.4 0.35 10.7 2.4 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Pkinase_Tyr PF07714.15 118460.2_03727001_3 - 4.1e-50 170.3 0.0 8.8e-50 169.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Stress-antifung PF01657.15 118460.2_03727001_3 - 8.3e-49 164.0 14.6 1.1e-19 70.7 1.2 3.4 3 0 0 3 3 3 3 Salt stress response/antifungal Pkinase PF00069.23 118460.2_03727001_3 - 7.5e-44 149.9 0.0 1.1e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.21 118460.2_03727001_3 - 0.0011 18.8 0.1 0.0025 17.7 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family DIOX_N PF14226.4 202866.2_03723001_1 - 3.2e-16 60.0 0.0 4.5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.18 202866.2_03723001_2 - 1.7e-23 82.8 0.0 3.4e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PH PF00169.27 001341634.1_03723001_3 - 0.0004 20.7 0.0 0.00082 19.7 0.0 1.5 1 0 0 1 1 1 1 PH domain IncA PF04156.12 001341634.1_03723001_3 - 0.0061 16.2 0.7 0.0096 15.6 0.7 1.2 1 0 0 1 1 1 1 IncA protein RasGAP_C PF03836.13 001341634.1_03723001_3 - 0.065 13.3 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 RasGAP C-terminus DUF4376 PF14301.4 001341634.1_03723001_3 - 0.096 12.9 0.0 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) Tmemb_cc2 PF10267.7 001341634.1_03723001_3 - 0.16 10.9 0.5 0.25 10.3 0.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MA3 PF02847.15 118613.3_03726001_3 - 5e-111 364.6 3.0 1e-29 102.7 0.1 4.2 4 0 0 4 4 4 4 MA3 domain MinE PF03776.12 118613.3_03726001_3 - 0.03 14.2 0.1 3.8 7.4 0.1 2.7 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE MA3 PF02847.15 001341710.1_03726001_3 - 7.7e-111 364.0 3.0 1.1e-29 102.6 0.1 4.1 4 0 0 4 4 4 4 MA3 domain Rio2_N PF09202.9 001341710.1_03726001_3 - 0.035 14.2 0.0 8.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Rio2, N-terminal MinE PF03776.12 001341710.1_03726001_3 - 0.037 13.9 0.1 4.1 7.3 0.1 2.7 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE DUF3128 PF11326.6 001341728.1_03723001_2 - 8.8e-15 54.7 0.1 8.8e-15 54.7 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3128) AP2 PF00847.18 118681.4_03723001_3 - 4.1e-13 49.2 1.1 6.8e-13 48.5 0.2 1.9 2 0 0 2 2 2 1 AP2 domain ANTH PF07651.14 118727.5_03725001_1 - 1e-99 332.9 0.1 1.4e-99 332.4 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.18 118727.5_03725001_1 - 2.4e-05 24.3 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ENTH domain RR_TM4-6 PF06459.10 118727.5_03725001_1 - 0.48 10.1 8.1 0.98 9.1 8.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4484 PF14831.4 118727.5_03725001_1 - 0.56 10.1 5.2 1.1 9.2 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Na_trans_assoc PF06512.11 118727.5_03725001_1 - 1.4 9.1 9.0 3.1 8.0 9.0 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated zf-RING_2 PF13639.4 118773.4_03724001_1 - 4.3e-13 49.1 7.5 4.3e-13 49.1 7.5 2.9 4 0 0 4 4 2 1 Ring finger domain zinc_ribbon_9 PF14369.4 118773.4_03724001_1 - 9.9e-12 44.8 2.2 9.9e-12 44.8 2.2 2.3 2 0 0 2 2 2 1 zinc-ribbon zf-C3HC4_2 PF13923.4 118773.4_03724001_1 - 8.6e-10 38.2 7.5 8.6e-10 38.2 7.5 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.3 118773.4_03724001_1 - 3e-09 36.3 3.6 3e-09 36.3 3.6 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.23 118773.4_03724001_1 - 2.1e-06 27.4 6.3 2.1e-06 27.4 6.3 3.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 118773.4_03724001_1 - 3.8e-06 27.0 7.9 3.8e-06 27.0 7.9 2.6 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.4 118773.4_03724001_1 - 0.00017 21.4 1.9 0.00017 21.4 1.9 3.7 4 1 0 4 4 4 1 RING-type zinc-finger zf-ANAPC11 PF12861.5 118773.4_03724001_1 - 0.0011 18.8 1.2 0.0011 18.8 1.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.4 118773.4_03724001_1 - 0.0013 18.4 10.9 0.013 15.2 3.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 118773.4_03724001_1 - 0.0018 18.1 13.3 0.0038 17.0 4.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.4 118773.4_03724001_1 - 0.01 15.5 12.4 0.15 11.8 5.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.12 118773.4_03724001_1 - 0.017 14.8 1.6 2.4 7.9 0.4 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-HC5HC2H PF13771.4 118773.4_03724001_1 - 0.065 13.3 5.3 0.54 10.4 0.9 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.4 118773.4_03724001_1 - 0.29 11.2 5.9 0.63 10.1 0.6 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain FANCL_C PF11793.6 118773.4_03724001_1 - 0.64 10.1 8.6 0.29 11.2 3.9 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain DUF1272 PF06906.9 118773.4_03724001_1 - 1 9.3 6.2 9.3 6.3 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.5 118773.4_03724001_1 - 1.3 9.0 6.9 4.3 7.3 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon PPR_2 PF13041.4 118814.3_03724001_3 - 6.3e-103 336.7 25.7 1e-15 57.5 0.2 9.6 1 1 9 10 10 10 10 PPR repeat family PPR_1 PF12854.5 118814.3_03724001_3 - 9.1e-88 287.5 5.3 1.4e-12 47.0 0.0 10.2 10 0 0 10 10 10 9 PPR repeat PPR PF01535.18 118814.3_03724001_3 - 1.5e-61 200.3 16.4 9.7e-08 31.6 0.4 10.4 10 0 0 10 10 10 9 PPR repeat PPR_3 PF13812.4 118814.3_03724001_3 - 4.4e-47 157.9 9.6 2.8e-12 46.4 0.0 6.3 4 2 2 6 6 6 6 Pentatricopeptide repeat domain PPR_long PF17177.2 118814.3_03724001_3 - 1.4e-20 73.4 0.0 1.1e-07 31.3 0.0 4.2 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PROPR RPM2 PF08579.9 118814.3_03724001_3 - 0.041 14.1 0.2 31 4.8 0.0 3.7 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) Tryp_alpha_amyl PF00234.20 118850.3_03722001_2 - 6.3e-09 36.0 18.2 4.8e-08 33.2 18.1 2.0 1 1 1 2 2 2 1 Protease inhibitor/seed storage/LTP family Branch PF02485.19 001341851.1_03724001_1 - 5.4e-77 258.5 0.1 6.9e-77 258.1 0.1 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme SLR1-BP PF07333.10 001036669.2_03721001_2 - 1.3e-14 54.3 10.7 2.1e-14 53.6 10.7 1.3 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Gamma-thionin PF00304.18 001036669.2_03721001_2 - 4.3 7.5 12.5 0.95 9.6 9.4 1.6 2 0 0 2 2 2 0 Gamma-thionin family Cu_bind_like PF02298.15 119205.3_03722001_1 - 2.2e-26 91.6 0.2 3.3e-26 91.0 0.2 1.3 1 0 0 1 1 1 1 Plastocyanin-like domain MAT1 PF06391.11 001342041.1_03723001_1 - 4.5e-22 78.7 1.7 8e-21 74.6 0.5 2.2 2 0 0 2 2 2 2 CDK-activating kinase assembly factor MAT1 ERCC4 PF02732.13 119234.4_03725001_3 - 1.6e-18 67.2 0.1 3.2e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain Pkinase_Tyr PF07714.15 001342055.1_03726001_3 - 1.1e-48 165.6 0.3 2e-48 164.8 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001342055.1_03726001_3 - 3.8e-47 160.7 1.1 5.7e-47 160.2 0.6 1.5 2 0 0 2 2 2 1 Protein kinase domain WAK PF08488.9 001342055.1_03726001_3 - 3.1e-37 127.1 2.1 1.1e-36 125.3 2.1 2.0 1 0 0 1 1 1 1 Wall-associated kinase GUB_WAK_bind PF13947.4 001342055.1_03726001_3 - 1.8e-22 80.1 0.8 1.8e-22 80.1 0.8 2.9 3 0 0 3 3 3 1 Wall-associated receptor kinase galacturonan-binding EGF_CA PF07645.13 001342055.1_03726001_3 - 9.4e-06 25.6 3.5 9.4e-06 25.6 3.5 2.7 2 0 0 2 2 2 1 Calcium-binding EGF domain PIP49_C PF12260.6 001342055.1_03726001_3 - 0.0012 18.4 0.0 0.0034 16.9 0.0 1.7 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Myc_N PF01056.16 001342055.1_03726001_3 - 0.066 12.9 2.4 0.1 12.3 2.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Fumble PF03630.12 001125620.1_03727001_1 - 9e-135 449.0 0.1 1.1e-134 448.7 0.1 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.17 001125620.1_03727001_1 - 1.7e-30 106.1 0.0 2.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Atrophin-1 PF03154.13 001125627.1_03723001_1 - 2.1 6.4 7.2 2.8 6.0 7.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family ATP-synt_C PF00137.19 001125627.1_03723001_2 - 7.8e-19 67.6 24.9 3e-14 53.0 13.5 3.8 4 0 0 4 4 4 2 ATP synthase subunit C Atrophin-1 PF03154.13 001125627.1_03723001_2 - 0.0038 15.5 5.9 0.0048 15.1 5.9 1.0 1 0 0 1 1 1 1 Atrophin-1 family DUF3915 PF13054.4 001125627.1_03723001_2 - 0.026 14.4 2.2 0.026 14.4 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Apis_Csd PF11671.6 001125627.1_03723001_2 - 0.68 9.8 7.2 1 9.2 7.2 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein G0-G1_switch_2 PF15103.4 001125627.1_03723001_2 - 0.69 10.2 4.0 2.7 8.3 0.1 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 C1-set_C PF16196.3 001125627.1_03723001_2 - 2.7 7.4 8.5 0.57 9.5 0.6 3.2 3 0 0 3 3 3 0 C1-set C-terminal domain DUF3915 PF13054.4 001125627.1_03723001_3 - 1.2 8.9 4.8 2 8.3 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Lzipper-MIP1 PF14389.4 001342199.1_03723001_2 - 7.6e-19 67.6 5.9 7.6e-19 67.6 5.9 1.8 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 betaPIX_CC PF16523.3 001342199.1_03723001_2 - 0.5 10.1 7.2 2.7 7.7 0.4 2.3 1 1 1 2 2 2 0 betaPIX coiled coil Sacchrp_dh_C PF16653.3 119469.4_03728001_2 - 4.2e-87 292.4 0.0 6e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.13 119469.4_03728001_2 - 7.8e-25 87.6 0.0 1.8e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Saccharop_dh_N PF04455.10 119469.4_03728001_2 - 7.2e-23 80.7 0.1 1.7e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region Sacchrp_dh_NADP PF03435.16 119469.4_03728001_2 - 1.8e-16 60.4 2.0 6.1e-15 55.5 2.0 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.19 119469.4_03728001_2 - 0.048 12.8 0.0 0.75 8.9 0.0 2.7 2 2 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PORR PF11955.6 148393.3_03724001_3 - 1.8e-113 378.7 1.2 2.5e-113 378.2 1.2 1.2 1 0 0 1 1 1 1 Plant organelle RNA recognition domain Auxin_inducible PF02519.12 119643.3_03722001_3 - 1.5e-25 89.0 0.0 1.9e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Auxin responsive protein RWP-RK PF02042.13 119724.2_03723001_1 - 1.4e-21 76.1 0.1 3.1e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain eIF3_p135 PF12807.5 119724.2_03723001_1 - 0.013 15.4 1.2 0.013 15.4 1.2 2.3 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit 135 Pkinase_Tyr PF07714.15 119725.5_03724001_2 - 4e-49 167.1 0.0 5.2e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 119725.5_03724001_2 - 2e-44 151.8 0.0 3.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.21 119725.5_03724001_2 - 0.094 12.5 0.0 0.76 9.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DA1-like PF12315.6 001342424.1_03725001_1 - 1.1e-55 188.1 0.6 2.1e-55 187.2 0.6 1.4 1 0 0 1 1 1 1 Protein DA1 LIM PF00412.20 001342424.1_03725001_1 - 5.7e-08 32.7 5.3 5.7e-08 32.7 5.3 3.0 2 1 1 3 3 3 2 LIM domain LAP1C PF05609.10 001342424.1_03725001_1 - 6.9 5.5 11.6 9.7 5.0 11.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cwf_Cwc_15 PF04889.10 001342424.1_03725001_1 - 8.5 5.9 19.5 14 5.2 19.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DA1-like PF12315.6 001342424.1_03725001_3 - 1.5e-37 128.8 0.0 2.1e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein DA1 Patatin PF01734.20 001085037.2_03723001_1 - 2.2e-21 76.8 0.1 4.3e-21 75.9 0.1 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase GH3 PF03321.11 119902.4_03725001_3 - 6.3e-208 691.8 0.0 8e-208 691.4 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter AIG2_2 PF13772.4 119902.4_03725001_3 - 0.13 12.6 0.0 0.43 10.9 0.0 1.9 1 0 0 1 1 1 0 AIG2-like family PSK PF06404.10 119934.2_03721001_1 - 1.4e-15 57.9 3.0 4.9e-15 56.2 3.0 1.7 1 1 0 1 1 1 1 Phytosulfokine precursor protein (PSK) Glyco_hydro_35 PF01301.17 001160820.1_03727001_1 - 7.7e-102 341.0 0.5 1.3e-101 340.3 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 PRP1_N PF06424.10 001160820.1_03727001_1 - 7.6e-48 162.3 1.2 7.6e-48 162.3 1.2 2.4 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal Gal_Lectin PF02140.16 001160820.1_03727001_1 - 8.7e-20 70.8 2.9 1.9e-19 69.7 2.9 1.6 1 0 0 1 1 1 1 Galactose binding lectin domain Glyco_hydro_42 PF02449.13 001160820.1_03727001_1 - 8.3e-11 41.7 0.1 3.2e-10 39.8 0.1 1.8 1 1 0 1 1 1 1 Beta-galactosidase BUD22 PF09073.8 001160820.1_03727001_1 - 3e-05 23.4 10.4 4.8e-05 22.8 10.4 1.2 1 0 0 1 1 1 1 BUD22 DUF1777 PF08648.10 001160820.1_03727001_1 - 0.001 19.2 2.7 0.001 19.2 2.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) DUF3892 PF13031.4 001160820.1_03727001_1 - 0.017 15.6 0.0 0.053 14.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) Presenilin PF01080.15 001160820.1_03727001_1 - 0.25 9.9 0.6 0.37 9.4 0.6 1.2 1 0 0 1 1 1 0 Presenilin DUF4775 PF16001.3 001160820.1_03727001_1 - 0.47 9.7 18.6 0.79 8.9 18.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) DUF913 PF06025.10 001160820.1_03727001_1 - 1.2 7.9 5.5 2.3 6.9 5.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.10 001160820.1_03727001_1 - 1.5 8.4 9.9 3.6 7.2 9.9 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.4 001160820.1_03727001_1 - 2.7 7.6 20.2 0.064 12.8 13.0 2.0 3 0 0 3 3 3 0 FAM176 family DUF4820 PF16091.3 001160820.1_03727001_1 - 3.4 6.8 8.0 7.2 5.8 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CPSF100_C PF13299.4 001160820.1_03727001_1 - 4.2 7.4 8.7 11 6.1 8.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FancD2 PF14631.4 001160820.1_03727001_1 - 5.6 4.1 5.9 7.9 3.6 5.9 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Vfa1 PF08432.8 001160820.1_03727001_1 - 7.6 6.7 18.5 1 9.5 13.4 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.9 001160820.1_03727001_1 - 7.7 6.4 18.8 0.65 9.9 9.4 2.7 3 0 0 3 3 2 0 RXT2-like, N-terminal Glyco_hydro_35 PF01301.17 001160820.1_03727001_2 - 0.0035 16.9 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 SH3_9 PF14604.4 120062.1_03722001_1 - 5.5e-08 32.4 0.2 3.5e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.26 120062.1_03722001_1 - 3.9e-06 26.2 0.2 1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.15 120062.1_03722001_1 - 0.038 13.5 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain VQ PF05678.12 120133.4_03723001_3 - 2.3e-13 49.2 1.4 4.9e-13 48.2 1.4 1.6 1 0 0 1 1 1 1 VQ motif zf-RING_2 PF13639.4 120172.3_03724001_3 - 6.4e-14 51.8 7.5 1.3e-13 50.9 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 120172.3_03724001_3 - 2.5e-10 39.7 6.2 2.5e-10 39.7 6.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 120172.3_03724001_3 - 6.5e-09 35.4 6.9 1.6e-08 34.1 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 120172.3_03724001_3 - 3.7e-08 33.4 8.9 2.6e-07 30.7 8.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 120172.3_03724001_3 - 5e-06 26.2 7.1 1e-05 25.1 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 120172.3_03724001_3 - 5.2e-06 26.2 1.8 1.1e-05 25.2 1.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 120172.3_03724001_3 - 2.7e-05 23.8 3.6 4.6e-05 23.1 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 120172.3_03724001_3 - 5.1e-05 22.9 5.5 0.00011 21.9 5.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 120172.3_03724001_3 - 0.00018 21.3 4.2 0.00035 20.3 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 120172.3_03724001_3 - 0.00025 20.9 1.2 0.00046 20.0 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.3 120172.3_03724001_3 - 0.0011 18.4 4.1 0.002 17.6 4.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF4171 PF13775.4 120172.3_03724001_3 - 0.0041 17.4 0.4 0.0088 16.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4171) Baculo_RING PF05883.9 120172.3_03724001_3 - 0.033 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.6 120172.3_03724001_3 - 0.059 13.4 5.6 0.44 10.6 5.6 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Arc PF03869.12 120172.3_03724001_3 - 0.091 12.5 0.4 4 7.2 0.1 2.4 2 0 0 2 2 2 0 Arc-like DNA binding domain Prok-RING_1 PF14446.4 120172.3_03724001_3 - 0.1 12.4 2.1 3.5 7.5 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.4 120172.3_03724001_3 - 0.19 11.3 2.5 0.33 10.6 2.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.5 120172.3_03724001_3 - 0.78 9.8 6.7 1.6 8.7 6.7 1.6 1 0 0 1 1 1 0 RING-variant domain Ribosomal_L40e PF01020.15 144097.1_03724120_2 - 8.4e-05 22.2 5.0 0.00021 21.0 5.0 1.6 1 0 0 1 1 1 1 Ribosomal L40e family DUF3827 PF12877.5 141942.1_03721120_2 - 0.14 10.4 0.1 0.16 10.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ank_3 PF13606.4 141942.1_03721120_3 - 0.04 14.3 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.4 141942.1_03721120_3 - 0.079 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PPARgamma_N PF12577.6 142010.1_03721120_1 - 0.084 13.4 0.1 0.12 12.9 0.1 1.1 1 0 0 1 1 1 0 PPAR gamma N-terminal region Remorin_C PF03763.11 143999.1_03722120_1 - 0.03 14.1 6.5 0.041 13.7 6.5 1.1 1 0 0 1 1 1 0 Remorin, C-terminal region HOK_GEF PF01848.14 144002.1_03722120_1 - 0.081 12.2 1.0 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Hok/gef family NifU_N PF01592.14 142084.1_03722120_1 - 2.7e-05 24.1 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain COX2-transmemb PF09125.8 142356.1_03723120_3 - 0.12 12.0 0.8 0.26 11.0 0.8 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Kinesin PF00225.21 142389.1_03722120_2 - 8.9e-08 31.3 0.0 1.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Q_salvage PF10343.7 142400.1_03723120_1 - 0.0054 16.2 0.6 0.094 12.1 0.6 2.0 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Q_salvage PF10343.7 142403.1_03721120_3 - 0.0005 19.6 1.0 0.64 9.4 0.1 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family ITAM_Cys-rich PF10538.7 142403.1_03721120_3 - 0.82 9.3 0.1 0.82 9.3 0.1 2.7 3 0 0 3 3 3 0 Immunoreceptor tyrosine-based activation motif DUF547 PF04784.12 001345781.1_03725001_3 - 5.4e-37 126.1 0.0 9e-37 125.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Lzipper-MIP1 PF14389.4 001345781.1_03725001_3 - 5.5e-27 93.7 0.9 1.8e-26 92.1 0.5 2.1 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 RINGv PF12906.5 001161217.2_03722001_2 - 8.2e-11 41.7 10.2 1.8e-10 40.7 10.2 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.9 001161217.2_03722001_2 - 3.7 7.8 10.1 0.43 10.8 5.1 2.1 2 0 0 2 2 2 0 RING-like domain PP2 PF14299.4 001343880.1_03722001_1 - 5.5e-33 113.9 5.0 1.5e-17 63.9 0.6 2.3 1 1 1 2 2 2 2 Phloem protein 2 F-box PF00646.31 001343880.1_03722001_1 - 0.00072 19.2 1.5 0.0016 18.1 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.5 001343880.1_03722001_1 - 0.0021 17.8 0.1 0.0044 16.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like PRONE PF03759.11 120279.3_03725001_2 - 1.8e-185 615.8 0.3 2.2e-185 615.5 0.3 1.1 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) DUF4378 PF14309.4 001342654.1_03726001_2 - 5.6e-34 117.7 0.1 5.6e-34 117.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4378) DUF3741 PF12552.6 001342654.1_03726001_2 - 1.3e-15 56.9 0.1 4.4e-15 55.2 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3741) PPR_2 PF13041.4 001161222.2_03723001_3 - 4.7e-29 100.2 1.7 1.2e-13 50.9 0.0 4.6 1 1 3 4 4 4 4 PPR repeat family PPR PF01535.18 001161222.2_03723001_3 - 4.8e-20 70.2 3.9 1.8e-05 24.5 0.0 5.7 5 1 0 5 5 5 4 PPR repeat PPR_3 PF13812.4 001161222.2_03723001_3 - 3.7e-19 68.4 0.0 3e-10 39.9 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.5 001161222.2_03723001_3 - 1.5e-17 62.9 0.0 0.0005 19.6 0.0 5.3 4 1 1 5 5 5 4 PPR repeat PPR_long PF17177.2 001161222.2_03723001_3 - 3.1e-09 36.4 0.5 1e-08 34.7 0.5 1.7 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001161222.2_03723001_3 - 0.012 16.2 0.3 31 5.6 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.18 001161222.2_03723001_3 - 0.027 14.2 0.0 0.88 9.3 0.0 2.5 1 1 0 2 2 2 0 Region in Clathrin and VPS UPF0515 PF15135.4 001161222.2_03723001_3 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Glyco_trans_4_3 PF12000.6 001161222.2_03723001_3 - 0.15 11.7 0.1 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Gkycosyl transferase family 4 group Pkinase PF00069.23 001342723.1_03727001_2 - 5e-59 199.7 0.0 6.4e-35 120.7 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.15 001342723.1_03727001_2 - 1.1e-29 103.3 0.0 9.4e-19 67.6 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.4 001342723.1_03727001_2 - 0.015 14.5 0.0 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.12 001342723.1_03727001_2 - 0.15 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001342723.1_03727001_2 - 0.18 11.5 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM PF10378.7 001036752.3_03724001_2 - 0.75 9.4 4.3 0.66 9.6 0.9 2.1 2 0 0 2 2 2 0 Putative RRM domain F-box PF00646.31 001036752.3_03724001_3 - 0.00095 18.9 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001036752.3_03724001_3 - 0.0036 17.0 0.1 0.0069 16.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like THRAP3_BCLAF1 PF15440.4 001125693.1_03721001_3 - 0.037 12.9 0.2 0.044 12.7 0.2 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Atrophin-1 PF03154.13 120592.5_03724001_2 - 0.94 7.5 1.8 1.2 7.2 1.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family R3H PF01424.20 120592.5_03724001_3 - 8.9e-14 51.1 0.0 1.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 R3H domain SUZ PF12752.5 120592.5_03724001_3 - 9.1e-11 42.2 0.3 2.5e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 SUZ domain Myb_DNA-bind_4 PF13837.4 180443.2_03724001_3 - 9.8e-23 80.2 4.4 2.1e-22 79.2 4.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.5 180443.2_03724001_3 - 0.00022 21.8 3.5 0.00045 20.8 3.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.7 180443.2_03724001_3 - 0.015 15.5 2.0 0.015 15.5 2.0 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.29 180443.2_03724001_3 - 0.021 14.8 0.3 0.046 13.8 0.3 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 180443.2_03724001_3 - 0.049 13.7 0.7 0.12 12.5 0.4 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF573 PF04504.12 180443.2_03724001_3 - 0.062 13.8 0.3 0.14 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 PRONE PF03759.11 120676.3_03725001_1 - 2.9e-179 595.4 0.9 3.7e-179 595.0 0.9 1.1 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) MRP-L27 PF09809.7 120676.3_03725001_1 - 0.0025 17.5 0.3 0.005 16.5 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 PP2C PF00481.19 120758.4_03724001_3 - 1.2e-37 129.8 0.0 1.7e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 120758.4_03724001_3 - 0.001 18.6 0.1 0.002 17.7 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L7Ae PF01248.24 120901.4_03723001_1 - 4e-23 80.8 1.3 6e-23 80.3 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PC4 PF02229.14 120960.3_03722001_1 - 8.7e-18 63.6 0.0 1.4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Ribosomal_S19 PF00203.19 120988.3_03723001_1 - 4.4e-34 116.1 0.2 7e-34 115.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ldh_1_N PF00056.21 001125727.1_03723001_2 - 1.8e-46 157.6 0.2 2.5e-46 157.1 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001125727.1_03723001_2 - 1.3e-36 126.0 0.0 2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.17 001125727.1_03723001_2 - 0.00047 19.1 0.0 0.00067 18.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.22 001125727.1_03723001_2 - 0.024 15.0 0.3 0.057 13.7 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001125727.1_03723001_3 - 5.5e-06 26.3 0.0 7.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Dor1 PF04124.10 121236.2_03725001_2 - 2.5e-156 519.5 0.2 3e-156 519.2 0.2 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.9 121236.2_03725001_2 - 1.8e-10 40.6 0.0 1.8e-10 40.6 0.0 2.7 4 0 0 4 4 4 1 Vps51/Vps67 Exo84_C PF16528.3 121236.2_03725001_2 - 9.5e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps54_N PF10475.7 121236.2_03725001_2 - 0.006 15.8 1.3 0.01 15.0 1.3 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sec5 PF15469.4 121236.2_03725001_2 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec5 Sigma_reg_C PF13791.4 001203377.1_03727001_1 - 0.012 15.7 0.8 0.012 15.7 0.8 1.8 2 0 0 2 2 2 0 Sigma factor regulator C-terminal NAM PF02365.13 001343304.1_03724001_1 - 8.5e-19 68.1 0.1 1.5e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein Aa_trans PF01490.16 001343391.1_03724001_1 - 2.5e-60 204.2 32.5 3.2e-60 203.8 32.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.16 001036809.1_03723001_3 - 1.8e-44 152.0 23.1 9.5e-24 83.7 12.8 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Mito_carr PF00153.25 121568.3_03724001_3 - 7.9e-54 179.5 9.3 1.6e-19 69.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.14 121568.3_03724001_3 - 2.3 8.1 5.2 1.4 8.8 0.1 2.7 3 0 0 3 3 3 0 Colicin V production protein RCC1 PF00415.16 001343434.1_03723001_3 - 2.9e-65 216.6 17.7 1.5e-14 54.2 0.1 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 001343434.1_03723001_3 - 2.3e-45 151.4 24.7 9.8e-10 37.9 0.1 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat SET PF00856.26 121730.4_03724001_2 - 4.3e-13 49.9 0.0 7.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.9 121730.4_03724001_2 - 0.0048 17.5 0.0 0.0084 16.7 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Glycos_transf_3 PF00591.19 121804.5_03725001_2 - 1.3e-99 332.8 0.3 1.8e-99 332.4 0.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.15 121804.5_03725001_2 - 2.2e-13 49.7 0.7 5e-13 48.5 0.7 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain CIAPIN1 PF05093.11 121845.3_03723001_1 - 3.7e-18 65.8 13.3 2e-15 57.0 13.3 2.5 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_11 PF08241.10 121845.3_03723001_1 - 0.0034 17.9 0.0 0.0081 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain F-box PF00646.31 001343562.1_03724001_1 - 8.9e-09 34.9 0.1 3e-08 33.2 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001343562.1_03724001_1 - 0.0013 18.4 0.0 0.0038 16.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like SSXT PF05030.10 001343562.1_03724001_1 - 0.057 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Tub PF01167.16 001343562.1_03724001_3 - 1e-88 296.6 0.0 1.2e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.6 001343562.1_03724001_3 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) WPP PF13943.4 001343596.1_03725001_1 - 8.5e-33 112.6 0.0 2.3e-32 111.2 0.0 1.8 1 0 0 1 1 1 1 WPP domain LRR_6 PF13516.4 001343596.1_03725001_1 - 3.7e-19 67.0 11.4 0.024 14.5 0.0 9.2 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.5 001343596.1_03725001_1 - 1.8e-09 37.5 4.3 1 9.7 0.1 6.2 7 0 0 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001343596.1_03725001_1 - 0.0071 15.9 13.9 1.3 8.7 1.2 5.9 5 2 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.31 001343596.1_03725001_1 - 0.32 11.5 4.2 4.3e+02 2.0 0.0 6.5 7 1 0 7 7 7 0 Leucine Rich Repeat EST1_DNA_bind PF10373.7 121945.3_03728001_2 - 5.7e-73 245.7 0.0 1e-72 244.8 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.7 121945.3_03728001_2 - 1.7e-21 77.1 0.5 4e-21 75.9 0.5 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 Rhamno_transf PF11316.6 121945.3_03728001_2 - 0.031 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF538 PF04398.10 121964.4_03723001_1 - 6.2e-25 87.7 0.0 1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF538 NAD_binding_1 PF00175.19 122015.5_03724001_3 - 3.3e-30 104.8 0.0 4.8e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.22 122015.5_03724001_3 - 4e-25 87.9 0.0 7.1e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.10 122015.5_03724001_3 - 6.8e-05 22.9 0.0 0.0018 18.3 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain PC-Esterase PF13839.4 001085140.2_03725001_3 - 7.7e-76 255.4 0.0 1.1e-75 254.9 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.4 001085140.2_03725001_3 - 3.3e-15 56.0 5.0 9.2e-15 54.5 5.0 1.8 1 0 0 1 1 1 1 PMR5 N terminal Domain GAPT PF11770.6 001085140.2_03725001_3 - 0.019 14.7 0.3 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) POM121 PF15229.4 001085140.2_03725001_3 - 0.091 12.3 3.5 0.17 11.5 3.5 1.3 1 0 0 1 1 1 0 POM121 family Auxin_inducible PF02519.12 122088.4_03723001_1 - 2e-26 91.9 0.0 3.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Auxin responsive protein Mito_fiss_Elm1 PF06258.9 122140.4_03725001_2 - 1.2e-123 412.0 0.0 1.6e-123 411.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission ELM1 Epimerase_2 PF02350.17 122140.4_03725001_2 - 0.19 10.4 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase NAD_binding_4 PF07993.10 001343726.1_03725001_1 - 3.4e-06 26.3 0.0 4.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NAD_binding_4 PF07993.10 001343726.1_03725001_2 - 9e-05 21.6 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NAD_binding_4 PF07993.10 001343726.1_03725001_3 - 5.8e-50 169.7 0.1 4.2e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Sterile PF03015.17 001343726.1_03725001_3 - 8e-15 54.7 0.5 1.8e-14 53.6 0.5 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.19 001343726.1_03725001_3 - 0.053 12.8 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family LRR_2 PF07723.11 122165.1_03722001_1 - 3.1e-05 24.3 0.0 0.00016 22.1 0.0 2.4 1 0 0 1 1 1 1 Leucine Rich Repeat LRR_4 PF12799.5 122165.1_03722001_1 - 0.36 11.2 6.0 9.8 6.6 0.0 3.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) PWWP PF00855.15 122221.3_03729001_3 - 1.2e-15 57.6 0.1 3.2e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 PWWP domain CTD_bind PF04818.11 122221.3_03729001_3 - 4e-12 46.6 0.0 1.1e-11 45.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.6 122221.3_03729001_3 - 4.7e-07 29.7 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF789 PF05623.10 001343800.1_03723001_1 - 6.3e-57 193.4 0.0 1.7e-56 191.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF789) DUF789 PF05623.10 001343800.1_03723001_2 - 3.5e-15 56.3 0.0 4.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF789) Lipase_3 PF01764.23 001343854.1_03723001_1 - 2.5e-06 27.3 0.3 6e-06 26.1 0.3 1.6 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.5 001343854.1_03723001_1 - 0.0039 17.7 0.0 0.0047 17.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001343854.1_03723001_1 - 0.036 13.2 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.6 001343854.1_03723001_1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.11 001343854.1_03723001_1 - 0.091 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein HMA PF00403.24 001343881.1_03723001_2 - 1.5e-21 76.4 10.3 1.4e-12 47.7 2.5 2.5 2 1 0 2 2 2 2 Heavy-metal-associated domain Tox-PL-2 PF15643.4 001343881.1_03723001_2 - 0.0043 17.0 0.3 1.1 9.3 0.1 2.4 2 0 0 2 2 2 1 Papain fold toxin 2 TBP PF00352.19 001343881.1_03723001_2 - 0.11 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) CAP_N PF01213.17 001343881.1_03723001_2 - 0.29 10.5 8.3 0.29 10.4 1.4 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal BUD22 PF09073.8 001343881.1_03723001_2 - 0.48 9.6 19.6 0.0049 16.1 4.9 2.2 2 0 0 2 2 2 0 BUD22 DUF2052 PF09747.7 001343881.1_03723001_2 - 0.97 9.4 18.6 2.5 8.1 10.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF3987 PF13148.4 001343881.1_03723001_2 - 1.1 8.0 5.5 3 6.6 5.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tim54 PF11711.6 001343881.1_03723001_2 - 2.9 6.4 18.8 0.12 11.0 2.6 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SpoIIIAH PF12685.5 001343881.1_03723001_2 - 4.9 6.8 11.3 20 4.8 6.6 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.12 001343881.1_03723001_2 - 7.7 6.8 18.1 1.9 8.8 1.5 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 ABC1 PF03109.14 001343906.1_03725001_2 - 1.1e-28 99.7 0.1 4.1e-28 97.8 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.21 001343906.1_03725001_2 - 5.6e-06 26.3 0.0 0.00036 20.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.9 001343906.1_03725001_2 - 0.0068 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.20 001343906.1_03725001_2 - 0.011 15.2 0.0 0.036 13.5 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.23 001343906.1_03725001_2 - 0.016 14.5 0.1 0.13 11.5 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Pup PF05639.9 001343906.1_03725001_2 - 0.11 13.3 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 Pup-like protein Pkinase PF00069.23 001125805.1_03723001_3 - 1.4e-09 37.5 0.0 2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.12 001125805.1_03723001_3 - 7.4e-09 35.1 0.0 1.7e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001125805.1_03723001_3 - 1.1e-07 31.9 0.2 5.5e-05 23.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.20 001125805.1_03723001_3 - 4.2e-07 29.6 0.0 6.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.15 001125805.1_03723001_3 - 3.4e-06 26.4 0.0 4.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.18 001125805.1_03723001_3 - 0.0024 17.4 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.9 001125805.1_03723001_3 - 0.0054 16.2 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.18 001125805.1_03723001_3 - 0.014 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Golgin_A5 PF09787.7 001343981.1_03723001_2 - 0.14 11.5 40.9 0.78 9.0 11.9 3.5 1 1 3 4 4 4 0 Golgin subfamily A member 5 Reo_sigmaC PF04582.10 001343981.1_03723001_2 - 0.2 10.9 5.7 0.84 8.8 3.6 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF745 PF05335.11 001343981.1_03723001_2 - 0.67 9.5 19.7 0.11 12.1 12.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Laminin_II PF06009.10 001343981.1_03723001_2 - 2.1 8.3 20.5 0.86 9.5 4.9 3.4 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.10 001343981.1_03723001_2 - 2.8 7.8 23.1 0.16 11.8 2.9 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) PPR_2 PF13041.4 001344000.1_03727001_1 - 2.2e-99 325.4 27.3 1.2e-10 41.3 0.8 18.8 9 4 11 20 20 20 17 PPR repeat family PPR PF01535.18 001344000.1_03727001_1 - 1.3e-92 297.7 52.9 1.4e-07 31.1 0.7 22.4 22 0 0 22 22 22 18 PPR repeat PPR_3 PF13812.4 001344000.1_03727001_1 - 2e-59 197.4 2.9 3.6e-12 46.0 0.0 11.3 9 3 3 12 12 12 10 Pentatricopeptide repeat domain PPR_1 PF12854.5 001344000.1_03727001_1 - 2.5e-47 158.1 11.8 9e-05 22.0 0.0 18.1 19 0 0 19 19 19 9 PPR repeat PPR_long PF17177.2 001344000.1_03727001_1 - 7.6e-34 116.8 8.4 6.6e-09 35.3 0.0 6.8 2 2 6 9 9 9 7 Pentacotripeptide-repeat region of PROPR TPR_14 PF13428.4 001344000.1_03727001_1 - 4.8e-06 26.8 0.1 68 4.6 0.0 9.0 10 3 3 13 13 10 0 Tetratricopeptide repeat TPR_7 PF13176.4 001344000.1_03727001_1 - 0.00028 20.6 0.0 2.3 8.3 0.0 6.6 8 0 0 8 8 7 1 Tetratricopeptide repeat RPM2 PF08579.9 001344000.1_03727001_1 - 0.001 19.2 0.1 0.96 9.7 0.0 4.1 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_2 PF07719.15 001344000.1_03727001_1 - 0.0041 17.0 5.5 56 4.1 0.1 7.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.4 001344000.1_03727001_1 - 0.0058 16.3 0.3 0.14 12.0 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat MNE1 PF13762.4 001344000.1_03727001_1 - 0.015 15.2 1.2 24 4.8 0.0 4.1 3 1 0 3 3 3 0 Mitochondrial splicing apparatus component Mrr_N PF14338.4 001344000.1_03727001_1 - 0.15 12.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Mrr N-terminal domain Pkinase PF00069.23 001344064.1_03724001_3 - 5.9e-43 147.0 0.0 8.5e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001344064.1_03724001_3 - 6.6e-31 107.4 0.0 9.7e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Prolamin_like PF05617.9 001085176.1_03721001_1 - 3.4e-08 33.4 0.2 5.3e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Prolamin-like Auxin_resp PF06507.11 001085203.1_03726001_1 - 4.1e-32 110.1 0.7 7.6e-32 109.3 0.7 1.5 1 0 0 1 1 1 1 Auxin response factor B3 PF02362.19 001085203.1_03726001_1 - 2.5e-21 75.3 0.0 2.3e-20 72.2 0.0 2.4 2 0 0 2 2 2 1 B3 DNA binding domain AUX_IAA PF02309.14 001085203.1_03726001_1 - 0.00028 20.7 12.1 0.00047 20.0 2.2 3.1 2 1 0 2 2 2 1 AUX/IAA family SIS_2 PF13580.4 001085203.1_03726001_1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 SIS domain PRP38 PF03371.13 001344186.1_03726001_2 - 2.6e-45 154.3 0.5 4.7e-29 101.3 0.1 2.2 2 0 0 2 2 2 2 PRP38 family PRP38_assoc PF12871.5 001344186.1_03726001_2 - 2.9e-06 27.6 88.5 1.6e+04 -5.8 23.1 2.9 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MIP-T3 PF10243.7 001344186.1_03726001_2 - 2.8 6.4 29.8 3.8 6.0 29.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pollen_allerg_1 PF01357.19 123288.3_03723001_1 - 9.9e-21 73.5 0.7 1.6e-20 72.8 0.7 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 123288.3_03723001_1 - 7e-19 67.8 0.0 1.5e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase DUF1666 PF07891.10 001344304.1_03725001_1 - 4.7e-93 311.3 10.8 8.9e-93 310.4 10.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1666) HI0933_like PF03486.12 001203511.1_03724001_3 - 2e-119 398.8 0.0 2.4e-119 398.6 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.22 001203511.1_03724001_3 - 1.6e-06 27.3 0.1 5e-05 22.4 0.1 2.2 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.12 001203511.1_03724001_3 - 4.6e-06 26.0 0.2 1.8e-05 24.0 0.2 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.4 001203511.1_03724001_3 - 0.0026 16.9 0.4 0.054 12.6 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.20 001203511.1_03724001_3 - 0.005 15.9 0.5 1.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.4 001203511.1_03724001_3 - 0.014 15.5 0.2 0.036 14.2 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.22 001203511.1_03724001_3 - 0.041 13.4 1.7 0.84 9.1 1.1 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.5 001203511.1_03724001_3 - 0.089 12.0 0.9 0.21 10.8 1.1 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.15 001203511.1_03724001_3 - 0.11 11.6 0.2 0.25 10.4 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.10 001203511.1_03724001_3 - 0.2 10.5 0.2 0.31 9.9 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2199 PF09965.7 123435.4_03723001_3 - 0.009 15.9 0.2 0.035 14.0 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2199) NESP55 PF06390.10 123435.4_03723001_3 - 0.074 12.5 3.3 0.11 11.9 3.3 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF2199 PF09965.7 001036911.3_03723001_1 - 0.014 15.3 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) NESP55 PF06390.10 001036911.3_03723001_1 - 0.24 10.8 5.2 0.21 11.0 4.1 1.4 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pkinase PF00069.23 123564.3_03725001_1 - 3e-52 177.5 0.1 6e-52 176.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 123564.3_03725001_1 - 5.9e-37 127.2 0.0 8.5e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3533 PF12051.6 123564.3_03725001_3 - 2 7.1 9.5 2.8 6.7 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) 2OG-FeII_Oxy PF03171.18 001344483.1_03723001_2 - 0.00064 20.0 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.18 001344483.1_03723001_3 - 1.6e-18 66.9 0.1 4.4e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.4 001344483.1_03723001_3 - 4.2e-17 62.9 0.0 6.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MatE PF01554.16 123772.3_03724001_2 - 3.1e-59 199.1 33.4 3.2e-32 111.3 12.6 2.5 2 0 0 2 2 2 2 MatE Peptidase_S8 PF00082.20 001344556.1_03726001_1 - 4.8e-48 163.8 2.0 8.3e-48 163.0 2.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.14 001344556.1_03726001_1 - 3.9e-24 84.9 0.6 9.7e-24 83.7 0.6 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Phage_Gp23 PF10669.7 001161289.2_03721001_3 - 0.093 12.9 0.1 5.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Med3 PF11593.6 001161289.2_03721001_3 - 1.7 7.6 10.7 1.9 7.5 10.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal potato_inhibit PF00280.16 001344605.1_03721001_1 - 1.9e-16 60.3 0.0 1.9e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Potato inhibitor I family NB-ARC PF00931.20 001344627.1_03726001_2 - 0.0034 16.3 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.4 001344627.1_03726001_2 - 0.14 11.8 1.8 3.2 7.4 0.1 3.3 3 1 0 3 3 3 0 Leucine rich repeat Peptidase_C48 PF02902.17 123925.1_03726001_1 - 6.2e-49 166.6 0.7 1.4e-48 165.5 0.7 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1985 PF09331.9 123925.1_03726001_1 - 2.7e-30 105.0 0.0 2.7e-30 105.0 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1985) VWA_CoxE PF05762.12 123925.1_03726001_1 - 0.016 14.5 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein UBD PF16455.3 123941.3_03723001_1 - 2.7e-33 114.2 0.1 1.6e-32 111.7 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-binding domain bHLH-MYC_N PF14215.4 124046.2_03726001_3 - 7.9e-55 185.6 1.2 1e-54 185.2 0.2 1.7 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 124046.2_03726001_3 - 2e-10 40.3 0.1 5.6e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NUDIX PF00293.26 001344713.1_03724001_2 - 1.8e-13 50.5 0.0 3.9e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain SBP PF03110.12 124435.3_03725001_1 - 6.5e-30 103.0 14.1 1.2e-29 102.2 14.1 1.4 1 0 0 1 1 1 1 SBP domain M157 PF11624.6 124435.3_03725001_1 - 0.17 11.1 0.5 0.29 10.3 0.5 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 UQ_con PF00179.24 001203579.1_03723001_2 - 3.2e-42 143.4 0.0 4.4e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.29 001203579.1_03723001_2 - 2.6e-09 36.7 0.0 4.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.4 001203579.1_03723001_2 - 0.00014 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001203579.1_03723001_2 - 0.008 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain UEV PF05743.11 001203579.1_03723001_2 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 UEV domain Lipase_3 PF01764.23 124467.2_03724001_1 - 0.00038 20.2 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.5 124467.2_03724001_1 - 0.0017 18.9 0.1 0.0045 17.5 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 124467.2_03724001_1 - 0.11 11.6 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 BetaGal_dom4_5 PF13364.4 124467.2_03724001_2 - 0.082 13.4 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain RVT_3 PF13456.4 001036976.3_03723001_1 - 7.3e-25 86.9 0.1 1.2e-24 86.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.22 001036976.3_03723001_1 - 2.2e-10 40.7 0.0 3.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001036976.3_03723001_1 - 0.0066 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin UPF0172 PF03665.11 001085275.2_03722001_1 - 5.2e-11 42.8 0.0 7.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) MATH PF00917.24 124612.3_03723001_3 - 6.2e-24 84.2 0.2 1.4e-23 83.0 0.2 1.6 1 0 0 1 1 1 1 MATH domain DUF21 PF01595.18 001345010.1_03725001_2 - 2.9e-36 124.7 1.7 4.3e-36 124.1 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.26 001345010.1_03725001_2 - 7.8e-06 26.1 1.2 0.084 13.2 0.1 3.7 4 0 0 4 4 4 3 CBS domain DUF761 PF05553.9 124810.4_03723001_3 - 2.1e-16 59.0 2.0 4e-16 58.1 2.0 1.5 1 0 0 1 1 1 1 Cotton fibre expressed protein DUF4408 PF14364.4 124810.4_03723001_3 - 8.6e-14 50.8 4.9 1.9e-13 49.7 4.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4408) ATP-synt_J PF04911.10 124810.4_03723001_3 - 0.036 13.5 0.5 0.074 12.5 0.5 1.5 1 0 0 1 1 1 0 ATP synthase j chain WD40 PF00400.30 124832.3_03724001_1 - 1.2e-19 70.1 11.0 0.00019 22.0 0.6 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 124832.3_03724001_1 - 1.3e-09 38.1 0.4 0.011 15.9 0.0 4.1 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 124832.3_03724001_1 - 0.0012 17.8 0.0 0.58 8.9 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.6 124832.3_03724001_1 - 0.024 12.8 0.0 0.89 7.7 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Kinesin PF00225.21 124848.3_03727001_1 - 1.1e-108 363.0 0.1 2.9e-108 361.6 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.3 124848.3_03727001_1 - 2.2e-57 193.1 0.0 5.6e-57 191.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding EzrA PF06160.10 124848.3_03727001_1 - 1.4e-05 23.3 19.6 1.4e-05 23.3 19.6 2.2 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.10 124848.3_03727001_1 - 0.015 14.6 10.5 0.017 14.4 4.1 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CALCOCO1 PF07888.9 124848.3_03727001_1 - 1.9 6.8 37.5 0.39 9.1 33.1 1.8 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like tRNA-synt_2 PF00152.18 124848.3_03727001_1 - 7.6 5.4 9.9 1.8e+02 0.8 9.9 2.1 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) T3SS_needle_E PF08988.8 124848.3_03727001_1 - 8 6.6 14.9 0.44 10.6 1.3 3.9 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle LPP PF04728.11 124848.3_03727001_1 - 8.4 6.7 12.9 8 6.8 0.6 4.3 2 2 1 3 3 3 0 Lipoprotein leucine-zipper PGG PF13962.4 124851.1_03723001_1 - 9.4e-27 93.0 5.7 1.5e-26 92.4 5.7 1.3 1 0 0 1 1 1 1 Domain of unknown function Ank_2 PF12796.5 124851.1_03723001_1 - 9.7e-15 54.8 0.9 3.8e-07 30.5 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.4 124851.1_03723001_1 - 2.7e-10 39.4 0.2 0.13 12.8 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.4 124851.1_03723001_1 - 2.1e-09 37.6 0.0 0.0014 19.0 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.4 124851.1_03723001_1 - 5e-05 23.4 0.0 0.75 10.1 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.28 124851.1_03723001_1 - 5.7e-05 23.2 9.0 0.18 12.2 0.0 5.1 7 0 0 7 7 7 2 Ankyrin repeat TerB PF05099.11 124851.1_03723001_1 - 0.047 13.5 0.6 29 4.5 0.0 3.4 1 1 3 4 4 4 0 Tellurite resistance protein TerB Neurensin PF14927.4 124987.3_03723001_3 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Neurensin DUF2273 PF10031.7 124987.3_03723001_3 - 0.13 12.1 4.2 0.27 11.2 4.2 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Cytokin-bind PF09265.8 125079.3_03724001_3 - 2.3e-113 378.1 0.6 2.9e-113 377.8 0.6 1.1 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.21 125079.3_03724001_3 - 2.8e-20 72.4 0.0 4e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain PI-PLC-X PF00388.17 125254.2_03725001_1 - 5.9e-46 155.5 0.0 9e-46 154.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.17 125254.2_03725001_1 - 3.9e-27 94.8 0.0 8e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.28 125254.2_03725001_1 - 1.4e-11 44.5 0.0 2.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.9 125254.2_03725001_1 - 0.00032 21.0 0.0 0.00088 19.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like RRM_1 PF00076.20 001125989.1_03723001_1 - 1.1e-12 47.4 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.4 001125989.1_03723001_2 - 7.7e-10 39.1 8.1 1.1e-09 38.5 8.1 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 zf-RING_4 PF14570.4 125410.3_03728001_2 - 5.3e-21 73.9 11.9 1e-20 73.0 11.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.20 125410.3_03728001_2 - 2.5e-06 27.1 0.0 6.5e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.9 125410.3_03728001_2 - 7.3e-05 22.6 1.8 0.00016 21.5 1.8 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.4 125410.3_03728001_2 - 8.6e-05 22.2 8.3 0.00025 20.7 8.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 125410.3_03728001_2 - 0.024 14.8 11.2 0.053 13.7 11.2 1.6 1 0 0 1 1 1 0 Ring finger domain Rtf2 PF04641.10 125410.3_03728001_2 - 0.086 12.1 4.3 0.14 11.3 4.3 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-UDP PF14569.4 125410.3_03728001_2 - 0.4 10.7 5.6 0.87 9.6 5.6 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.19 125410.3_03728001_2 - 0.53 10.3 5.2 1.3 9.1 5.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_4 PF14447.4 125410.3_03728001_2 - 0.7 9.7 7.3 12 5.7 7.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.5 125410.3_03728001_2 - 3 7.8 6.9 36 4.4 6.9 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4 PF00097.23 125410.3_03728001_2 - 9.1 6.1 9.4 23 4.8 9.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prenyltransf PF01255.17 125443.1_03723001_2 - 1.5e-63 214.2 0.0 2.1e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Root_cap PF06830.9 125446.4_03724001_3 - 2.6e-27 94.6 0.0 4.3e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Root cap DUF1510 PF07423.9 125446.4_03724001_3 - 3.7e-07 29.7 22.2 3.7e-07 29.7 22.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) CAC1F_C PF16885.3 125446.4_03724001_3 - 0.013 15.1 5.6 0.018 14.6 5.6 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SAPS PF04499.13 125446.4_03724001_3 - 0.67 8.5 13.8 0.9 8.1 13.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF410 PF04190.11 001345584.1_03723001_2 - 4.9e-69 232.8 0.0 6.6e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_19 PF14559.4 001345584.1_03723001_2 - 0.072 13.5 0.1 4.5 7.7 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.21 125791.3_03728001_3 - 5.5e-51 173.2 0.0 1.1e-50 172.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.29 125791.3_03728001_3 - 3.7e-19 69.0 0.0 9.3e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 125791.3_03728001_3 - 5.3e-09 36.2 0.0 1.6e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.4 125791.3_03728001_3 - 1.1e-05 24.3 0.0 2.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 GCOM2 PF15328.4 125791.3_03728001_3 - 0.0016 18.7 0.4 0.0016 18.7 0.4 2.4 2 0 0 2 2 2 1 Putative GRINL1B complex locus protein 2 RRM_1 PF00076.20 125816.4_03724001_2 - 1.1e-20 73.1 0.0 1.6e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 125816.4_03724001_2 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.6 125816.4_03724001_2 - 0.029 14.3 1.4 0.059 13.3 0.1 2.1 2 0 0 2 2 2 0 Limkain b1 RRM_5 PF13893.4 125816.4_03724001_2 - 0.085 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) His_Phos_1 PF00300.20 001085326.1_03723001_3 - 2e-10 40.5 0.0 0.00043 19.9 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pardaxin PF07425.9 001085326.1_03723001_3 - 0.016 14.7 0.0 0.064 12.7 0.0 2.0 1 0 0 1 1 1 0 Pardaxin NAM PF02365.13 125849.4_03723001_2 - 1.7e-21 76.7 0.3 3.4e-21 75.7 0.3 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein TPR_2 PF07719.15 125914.5_03725001_3 - 1.4e-28 96.5 12.9 5.4e-05 22.9 0.1 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.26 125914.5_03725001_3 - 1.2e-24 84.9 12.6 8.6e-06 25.2 0.0 8.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.4 125914.5_03725001_3 - 6.8e-18 63.9 7.1 3.8e-05 23.1 4.0 5.1 3 2 2 5 5 5 4 TPR repeat TPR_19 PF14559.4 125914.5_03725001_3 - 2.3e-17 63.1 4.3 0.0044 17.4 0.7 6.7 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.4 125914.5_03725001_3 - 1.6e-16 59.4 5.4 0.016 15.8 0.0 6.7 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.4 125914.5_03725001_3 - 1.1e-13 50.1 5.7 0.66 10.2 0.0 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.4 125914.5_03725001_3 - 9.9e-13 47.0 3.2 0.71 9.9 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.4 125914.5_03725001_3 - 7.5e-12 45.6 15.3 0.0013 19.3 2.1 5.8 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.4 125914.5_03725001_3 - 7.3e-11 42.1 13.2 0.0075 16.4 0.3 5.7 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.4 125914.5_03725001_3 - 1.1e-10 41.0 5.0 0.002 18.3 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.4 125914.5_03725001_3 - 7.3e-05 22.7 3.2 1.7 8.7 0.1 4.4 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.4 125914.5_03725001_3 - 0.00062 18.9 0.4 0.11 11.6 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.5 125914.5_03725001_3 - 0.0018 18.3 4.6 3.7 7.7 0.0 4.9 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.12 125914.5_03725001_3 - 0.0068 16.8 14.4 0.03 14.8 0.2 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.4 125914.5_03725001_3 - 0.014 15.9 10.2 14 6.4 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.4 125914.5_03725001_3 - 0.025 14.3 9.2 3.6 7.5 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 125914.5_03725001_3 - 0.029 14.3 0.2 5.6 7.0 0.1 3.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.7 125914.5_03725001_3 - 0.066 12.8 0.8 1.2 8.8 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain Alkyl_sulf_dimr PF14863.4 125914.5_03725001_3 - 0.093 13.1 0.0 0.75 10.1 0.0 2.4 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Glyco_transf_5 PF08323.9 001203694.1_03724001_2 - 3.5e-33 115.2 0.0 5.7e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.4 001203694.1_03724001_2 - 9.1e-05 22.8 0.0 0.00076 19.8 0.0 2.2 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.4 001203694.1_03724001_2 - 0.0039 17.1 0.0 0.072 13.0 0.0 2.7 1 1 1 2 2 2 1 Glycosyltransferase Family 4 FlgN PF05130.10 001203694.1_03724001_2 - 0.028 14.8 1.9 0.049 14.0 1.9 1.4 1 0 0 1 1 1 0 FlgN protein APG6 PF04111.10 001203694.1_03724001_2 - 0.032 13.5 5.5 0.061 12.6 5.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TSC22 PF01166.16 001203694.1_03724001_2 - 0.059 13.6 1.8 0.18 12.0 1.8 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3276 PF11680.6 001203694.1_03724001_2 - 0.13 12.2 0.1 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) zf-C4H2 PF10146.7 001203694.1_03724001_2 - 0.22 11.6 4.0 0.35 11.0 4.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein WD-3 PF09765.7 001345722.1_03723001_2 - 1.3e-37 129.6 0.2 1.7e-37 129.2 0.2 1.2 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.6 001345722.1_03723001_2 - 4.3e-32 110.0 2.6 7.3e-32 109.2 2.6 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.4 001345722.1_03723001_2 - 2.8e-05 24.1 4.2 9.2e-05 22.5 4.2 1.9 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 001345722.1_03723001_2 - 0.00025 21.1 1.4 0.00054 20.1 1.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-HC5HC2H PF13771.4 001345722.1_03723001_2 - 0.027 14.6 1.7 0.054 13.6 1.7 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-ANAPC11 PF12861.5 001345722.1_03723001_2 - 0.082 12.8 2.4 0.27 11.2 2.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger UQ_con PF00179.24 001345722.1_03723001_2 - 0.11 12.0 0.1 0.26 10.8 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme PPR PF01535.18 126048.3_03724001_2 - 2e-45 149.8 14.6 4.2e-09 35.9 0.1 11.5 13 0 0 13 13 13 8 PPR repeat PPR_2 PF13041.4 126048.3_03724001_2 - 1.4e-41 140.3 0.5 3.1e-10 40.0 0.0 9.3 7 3 3 10 10 10 7 PPR repeat family PPR_1 PF12854.5 126048.3_03724001_2 - 3.5e-19 68.1 0.9 0.0031 17.0 0.0 7.8 8 0 0 8 8 8 4 PPR repeat PPR_3 PF13812.4 126048.3_03724001_2 - 4.2e-16 58.6 0.0 7.1e-06 25.9 0.0 5.3 4 2 2 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.2 126048.3_03724001_2 - 6.3e-08 32.1 0.0 0.029 13.6 0.0 3.3 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PROPR Peptidase_M3 PF01432.18 126048.3_03724001_2 - 0.05 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M3 Aldolase_II PF00596.19 126048.3_03724001_2 - 0.082 12.7 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain UDPGT PF00201.16 126067.3_03724001_2 - 2.6e-21 75.9 0.0 4.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 126067.3_03724001_2 - 0.014 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CLTH PF10607.7 001345803.1_03726001_1 - 4.4e-19 68.7 0.0 1.4e-11 44.4 0.0 2.8 3 0 0 3 3 3 2 CTLH/CRA C-terminal to LisH motif domain CCDC24 PF15669.3 001345803.1_03726001_1 - 0.21 11.3 0.9 0.53 10.0 0.9 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NB-ARC PF00931.20 126089.3_03726001_3 - 3.1e-30 105.1 0.0 7.4e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain RPW8 PF05659.9 126089.3_03726001_3 - 6.1e-27 93.9 0.9 1.3e-26 92.8 0.9 1.6 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 LRR_4 PF12799.5 126089.3_03726001_3 - 6.7e-07 29.4 28.5 0.0025 18.0 0.6 7.4 5 1 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 126089.3_03726001_3 - 1.3e-06 27.9 2.4 1.3e-06 27.9 2.4 5.3 4 2 1 5 5 5 1 Leucine rich repeat AAA PF00004.27 126089.3_03726001_3 - 0.00042 20.6 0.0 0.0023 18.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 126089.3_03726001_3 - 0.00077 19.7 0.0 0.0022 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 126089.3_03726001_3 - 0.0013 18.9 0.0 0.0052 16.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain MSV199 PF10553.7 126089.3_03726001_3 - 0.068 13.3 0.1 0.068 13.3 0.1 2.2 3 0 0 3 3 2 0 MSV199 domain cobW PF02492.17 126089.3_03726001_3 - 0.075 12.5 0.0 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.10 126089.3_03726001_3 - 0.083 12.7 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.16 126089.3_03726001_3 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Efg1 PF10153.7 126089.3_03726001_3 - 0.11 12.7 0.4 0.25 11.6 0.4 1.5 1 0 0 1 1 1 0 rRNA-processing protein Efg1 AAA_25 PF13481.4 126089.3_03726001_3 - 0.13 11.7 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Glyco_hydro_43 PF04616.12 126154.4_03724001_2 - 2.6e-17 62.9 2.2 3.9e-17 62.4 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1659 PF07872.9 142527.1_03721120_2 - 0.29 10.7 1.9 5.2 6.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) SecE PF00584.18 142529.1_03722120_1 - 0.047 13.5 0.9 0.12 12.2 0.9 1.6 1 1 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Herpes_UL42 PF02282.14 144269.1_03723120_2 - 0.013 15.2 1.6 0.17 11.6 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase processivity factor (UL42) F-box PF00646.31 142555.1_03721120_1 - 5.1e-05 22.9 0.2 8.7e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 142555.1_03721120_1 - 0.0024 17.6 0.1 0.0052 16.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF4548 PF15081.4 142559.1_03721120_3 - 0.12 12.1 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) SdpI PF13630.4 142561.1_03721120_1 - 0.024 14.6 0.9 0.052 13.5 0.9 1.7 1 1 0 1 1 1 0 SdpI/YhfL protein family DUF3678 PF12435.6 142779.1_03721120_1 - 0.43 9.7 5.2 0.4 9.8 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) NapE PF06796.9 142779.1_03721120_2 - 2.1 7.8 5.1 3.5 7.1 5.1 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE ATHILA PF03078.13 142796.1_03721120_3 - 1.5e-27 96.5 0.7 1.6e-27 96.3 0.7 1.0 1 0 0 1 1 1 1 ATHILA ORF-1 family Equine_IAV_S2 PF06502.9 144247.1_03722120_1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein DUF1467 PF07330.10 142825.1_03721120_2 - 0.074 12.9 2.9 0.12 12.2 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) FBD PF08387.8 144253.1_03723120_1 - 0.017 14.8 0.3 0.033 13.9 0.3 1.5 1 0 0 1 1 1 0 FBD Cation_ATPase_N PF00690.24 144179.1_03724120_3 - 0.21 11.1 0.8 2.6 7.6 0.2 2.4 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus SAP PF02037.25 144286.1_03722120_3 - 0.00012 21.6 0.3 0.00018 21.1 0.3 1.3 1 0 0 1 1 1 1 SAP domain Peptidase_S64 PF08192.9 142939.1_03725120_1 - 0.00023 19.7 0.0 0.00035 19.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Arm PF00514.21 144259.1_03721120_2 - 0.011 15.6 0.2 6.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Arm_3 PF16186.3 144259.1_03721120_3 - 4.7e-06 25.9 0.9 6.6e-06 25.4 0.9 1.3 1 0 0 1 1 1 1 Atypical Arm repeat DUF2518 PF10726.7 143123.1_03721120_2 - 0.063 12.8 1.3 0.079 12.5 0.8 1.4 1 1 1 2 2 2 0 Protein of function (DUF2518) Ndc80_HEC PF03801.11 143156.1_03721120_2 - 0.094 12.2 0.7 0.22 11.0 0.7 1.6 1 1 0 1 1 1 0 HEC/Ndc80p family PQQ_3 PF13570.4 001136806.2_53724001_1 - 0.021 15.2 0.1 0.064 13.6 0.1 1.8 1 0 0 1 1 1 0 PQQ-like domain Prot_inhib_II PF02428.13 145322.1_53723120_1 - 1.2 9.5 5.9 0.33 11.3 2.4 1.8 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family zf-BED PF02892.13 145991.1_53723120_3 - 0.00023 21.0 0.3 0.0005 19.9 0.3 1.6 1 0 0 1 1 1 1 BED zinc finger Ribosomal_L2_C PF03947.16 001349861.1_53723001_2 - 1.5e-45 154.3 3.8 2.5e-45 153.6 3.8 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.21 001349861.1_53723001_2 - 4.3e-17 61.7 0.0 1.3e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Myb_DNA-binding PF00249.29 001155516.2_53723001_3 - 1.8e-29 101.5 0.6 2.4e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001155516.2_53723001_3 - 7.2e-17 61.2 0.5 3e-10 40.0 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF1534 PF07551.9 001155516.2_53723001_3 - 0.0015 18.0 2.4 0.36 10.5 4.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1534) TFIIB PF00382.17 001349830.1_53723001_1 - 5e-31 106.4 3.2 6.7e-20 70.8 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.10 001349830.1_53723001_1 - 5.4e-15 54.5 1.0 9.7e-15 53.7 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.21 001349830.1_53723001_1 - 6.3e-05 22.6 0.0 0.00019 21.1 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_S27e PF01667.15 001349830.1_53723001_1 - 0.00061 19.3 0.8 0.0015 18.1 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S27 zf-ribbon_3 PF13248.4 001349830.1_53723001_1 - 0.009 15.3 0.9 0.81 9.0 0.0 2.5 2 0 0 2 2 2 1 zinc-ribbon domain RB_B PF01857.18 001349830.1_53723001_1 - 0.031 14.2 0.2 0.14 12.1 0.1 1.9 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain zf-RING_9 PF13901.4 001349830.1_53723001_1 - 0.27 11.0 1.9 9.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Kazal_1 PF00050.19 146332.1_53723120_1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain F-box PF00646.31 146347.1_53722120_1 - 0.00059 19.5 2.6 0.0013 18.4 0.3 2.8 2 1 1 3 3 3 1 F-box domain F-box-like PF12937.5 146347.1_53722120_1 - 0.0032 17.2 3.1 0.0032 17.2 0.5 2.4 2 1 0 2 2 2 1 F-box-like RVT_2 PF07727.12 146346.1_53729120_1 - 0.0084 15.3 0.1 0.013 14.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FmdA_AmdA PF03069.13 146390.1_53723120_2 - 4.2e-08 32.3 0.0 5.5e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family FmdA_AmdA PF03069.13 146390.1_53723120_3 - 0.0086 14.9 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family Peptidase_S8 PF00082.20 001158955.2_53726001_2 - 8.5e-49 166.3 0.7 1.2e-48 165.8 0.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.14 001158955.2_53726001_2 - 7.1e-17 61.7 1.6 9.8e-17 61.2 0.3 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 PA PF02225.20 001158955.2_53726001_2 - 5.5e-13 48.7 0.1 1.7e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 PA domain GST_N_3 PF13417.4 001156414.2_53723001_1 - 6.4e-20 71.2 0.0 1.1e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001156414.2_53723001_1 - 5.4e-16 58.6 0.0 9.1e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001156414.2_53723001_1 - 4.7e-13 49.1 0.0 1.2e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001156414.2_53723001_1 - 5e-13 48.7 0.8 1.2e-12 47.4 0.8 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001156414.2_53723001_1 - 6.3e-09 35.8 0.3 1.4e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.3 001156414.2_53723001_1 - 1.8e-06 28.3 0.0 3.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001156414.2_53723001_1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 001156414.2_53723001_1 - 0.001 19.7 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Abhydrolase_3 PF07859.11 001156553.2_53723001_2 - 3.8e-46 157.5 2.5 4.9e-46 157.1 2.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.26 001156553.2_53723001_2 - 6.9e-10 38.3 0.0 1.7e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.7 001156553.2_53723001_2 - 1.2e-05 24.8 3.2 0.00059 19.3 3.2 2.3 1 1 0 1 1 1 1 Esterase PHB depolymerase Say1_Mug180 PF10340.7 001156553.2_53723001_2 - 3.8e-05 22.6 0.0 5.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Esterase PF00756.18 001156553.2_53723001_2 - 0.14 11.7 0.1 0.71 9.3 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Hydrophob_seed PF14547.4 001154710.2_53722001_2 - 4e-21 74.8 8.8 5.9e-21 74.3 8.8 1.3 1 0 0 1 1 1 1 Hydrophobic seed protein Tryp_alpha_amyl PF00234.20 001154710.2_53722001_2 - 3.4e-05 24.1 0.9 5.6e-05 23.4 0.9 1.3 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family LTP_2 PF14368.4 001154710.2_53722001_2 - 0.00076 19.4 4.4 0.0013 18.6 4.4 1.4 1 0 0 1 1 1 1 Probable lipid transfer DUF568 PF04526.11 001158816.2_53723001_3 - 1.3e-22 80.3 0.1 2.9e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF568) PsbQ PF05757.9 001158816.2_53723001_3 - 0.14 11.7 0.9 0.28 10.8 0.9 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Tom22 PF04281.11 001324061.1_53722001_1 - 2.6e-08 33.6 0.0 4.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 GRAS PF03514.12 001322273.1_53724001_3 - 4.4e-122 407.5 0.0 5.2e-122 407.3 0.0 1.0 1 0 0 1 1 1 1 GRAS domain family Kinesin PF00225.21 001350051.1_53728001_2 - 1.9e-94 316.2 0.0 2.9e-94 315.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.3 001350051.1_53728001_2 - 1.4e-42 145.0 0.1 3e-42 143.9 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding SHE3 PF17078.3 001350051.1_53728001_2 - 0.013 15.1 0.8 0.013 15.1 0.8 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF87 PF01935.15 001350051.1_53728001_2 - 0.38 10.6 2.0 15 5.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF5082 PF16888.3 001350051.1_53728001_2 - 0.75 10.0 3.7 1.2 9.4 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) SKA1 PF07160.10 001350051.1_53728001_2 - 1.2 8.8 8.6 0.23 11.2 4.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4200 PF13863.4 001350051.1_53728001_2 - 2.5 8.4 6.4 0.55 10.5 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Glyco_hydro_9 PF00759.17 001154065.2_53725001_3 - 5.1e-121 404.8 2.9 6e-121 404.6 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Ribosomal_S9 PF00380.17 001310510.1_53722001_1 - 2.6e-31 108.5 0.5 3.5e-31 108.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2102 PF09875.7 001310510.1_53722001_1 - 0.062 12.9 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Polysacc_synt_4 PF04669.11 001159224.2_53723001_2 - 1.2e-70 236.9 0.0 1.5e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis RRM_2 PF04059.10 146420.1_53729120_1 - 5.5e-23 80.9 0.2 1e-22 80.0 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 Auxin_inducible PF02519.12 001323025.1_53722001_2 - 2.3e-17 62.8 0.0 3.7e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Auxin responsive protein ANF_receptor PF01094.26 001349910.1_53727001_3 - 1.8e-82 277.1 0.3 3.1e-82 276.4 0.3 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001349910.1_53727001_3 - 7.6e-35 119.8 0.1 1.3e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.18 001349910.1_53727001_3 - 6.1e-22 78.0 0.0 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.4 001349910.1_53727001_3 - 6.6e-16 58.8 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Lig_chan-Glu_bd PF10613.7 001349910.1_53727001_3 - 3.3e-10 40.0 0.0 6.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF202 PF02656.13 001349910.1_53727001_3 - 0.82 10.0 3.2 39 4.6 3.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Auxin_inducible PF02519.12 001321398.1_53723001_3 - 2.6e-25 88.3 0.0 4.5e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Auxin responsive protein BAG PF02179.14 001152583.2_53724001_3 - 1.6e-07 31.5 2.3 1.6e-07 31.5 2.3 1.9 2 0 0 2 2 2 1 BAG domain IQ PF00612.25 001152583.2_53724001_3 - 0.00017 21.0 1.0 0.00037 19.9 1.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Latarcin PF10279.7 001152583.2_53724001_3 - 0.87 9.9 3.4 0.95 9.8 0.2 2.3 2 0 0 2 2 2 0 Latarcin precursor EKLF_TAD1 PF16832.3 001147973.2_53724001_2 - 2 8.2 4.4 1.6 8.5 0.6 2.8 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 1 UDPGT PF00201.16 001147973.2_53724001_3 - 1.8e-16 59.9 0.0 2.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GTP_EFTU PF00009.25 001156096.2_53724001_2 - 2.4e-57 193.5 0.1 3.5e-57 192.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001156096.2_53724001_2 - 1.8e-34 118.3 0.1 4.2e-34 117.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001156096.2_53724001_2 - 3.4e-17 62.5 3.7 3.4e-17 62.5 3.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001156096.2_53724001_2 - 0.00023 21.1 0.3 0.00067 19.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.14 001156096.2_53724001_2 - 0.046 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.17 001156096.2_53724001_2 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GDPD PF03009.15 001157492.2_53724001_3 - 6.7e-46 157.0 0.0 8.7e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family FmdE PF02663.12 001143179.1_53723001_3 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Glyco_hydro_1 PF00232.16 001143209.1_53723001_1 - 2.1e-113 379.0 1.8 6e-81 272.0 0.3 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Cellulase PF00150.16 001143209.1_53723001_1 - 0.042 13.1 0.0 0.64 9.3 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) WD40 PF00400.30 001155532.2_53723001_1 - 1.7e-24 85.5 14.9 6.6e-05 23.5 0.3 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001155532.2_53723001_1 - 8.9e-10 38.6 6.6 0.096 12.9 0.0 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain FSH1 PF03959.11 001150851.1_53723001_1 - 7.8e-49 166.1 0.0 9.8e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) CK_II_beta PF01214.16 001111504.2_53723001_3 - 8.4e-82 273.3 0.1 1e-81 273.0 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit GST_N PF02798.18 001111509.2_53722001_3 - 8.9e-18 64.3 0.0 1.5e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001111509.2_53722001_3 - 3.2e-15 56.2 0.0 5.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001111509.2_53722001_3 - 1.9e-13 50.3 0.0 3.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001111509.2_53722001_3 - 1.8e-12 47.3 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001111509.2_53722001_3 - 9.7e-08 31.7 0.1 2.2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001111509.2_53722001_3 - 3.2e-05 23.9 0.0 8.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001111509.2_53722001_3 - 0.037 13.7 0.0 0.093 12.4 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain B12D PF06522.9 001174728.1_53723001_2 - 7.7e-06 25.5 0.1 1.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit KOW PF00467.27 001150947.1_53723001_3 - 0.00013 21.7 3.2 0.00022 20.9 3.2 1.3 1 0 0 1 1 1 1 KOW motif Ribosomal_S4e PF00900.18 001150947.1_53723001_3 - 0.00028 20.6 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal family S4e HJURP_C PF12347.6 001150947.1_53723001_3 - 0.17 11.8 0.3 0.29 11.1 0.3 1.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Sugar_tr PF00083.22 001174752.1_53724001_1 - 7.3e-36 123.9 19.0 2e-32 112.5 10.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.14 001174752.1_53724001_1 - 5.6e-34 117.5 35.8 5.3e-25 87.9 20.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.12 001174752.1_53724001_1 - 7.8e-06 25.3 9.9 7.8e-06 25.3 9.9 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.4 001174752.1_53724001_1 - 2.7e-05 22.8 21.1 3e-05 22.6 4.4 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein DUF1129 PF06570.9 001174752.1_53724001_1 - 5.7 6.3 10.6 1.9 7.9 7.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RAG1_imp_bd PF12560.6 001150961.1_53724001_3 - 0.33 10.3 3.7 0.22 10.9 1.1 1.9 1 1 1 2 2 2 0 RAG1 importin binding Transposase_24 PF03004.12 001150963.1_53724001_3 - 4.5e-12 46.1 1.3 1.6e-11 44.4 1.3 2.0 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) Spc24 PF08286.9 001150963.1_53724001_3 - 0.27 11.4 3.3 0.96 9.6 3.3 2.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FtsL PF04999.11 001150963.1_53724001_3 - 0.28 11.1 3.0 0.14 12.0 0.4 1.8 2 0 0 2 2 2 0 Cell division protein FtsL Filament PF00038.19 001150963.1_53724001_3 - 0.29 10.5 9.3 1.1 8.7 9.4 1.9 1 1 0 1 1 1 0 Intermediate filament protein Mnd1 PF03962.13 001150963.1_53724001_3 - 0.6 9.8 9.4 0.13 12.0 5.3 1.9 2 0 0 2 2 2 0 Mnd1 family DivIC PF04977.13 001150963.1_53724001_3 - 2.1 8.0 4.2 0.75 9.5 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF1639 PF07797.12 001143361.1_53723001_3 - 8.9e-15 54.3 0.8 8.9e-15 54.3 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1639) Ribosomal_S3_C PF00189.18 001294268.1_53722001_1 - 4.6e-25 87.8 1.0 1.2e-24 86.5 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.15 001294268.1_53722001_1 - 9.3e-12 44.5 0.3 1.4e-11 43.9 0.3 1.3 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.6 001294268.1_53722001_1 - 0.027 14.8 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.3 001294268.1_53722001_1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus RRM_1 PF00076.20 001111629.2_53725001_1 - 1e-36 124.4 0.1 3e-14 52.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ish1 PF10281.7 001111629.2_53725001_1 - 0.00027 21.0 2.9 0.2 11.9 0.1 2.6 2 0 0 2 2 2 2 Putative stress-responsive nuclear envelope protein Nup35_RRM_2 PF14605.4 001111629.2_53725001_1 - 0.0017 18.1 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.3 001111629.2_53725001_1 - 0.014 15.4 0.0 0.63 10.1 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif RRM_5 PF13893.4 001111629.2_53725001_1 - 0.031 13.7 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.4 001111629.2_53725001_1 - 0.07 13.2 0.0 4 7.5 0.0 3.0 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_2 PF04059.10 001111629.2_53725001_1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif 2 PAH PF02671.19 001151065.2_53722001_2 - 3.2e-10 39.9 0.3 7.1e-10 38.8 0.1 1.7 2 0 0 2 2 2 1 Paired amphipathic helix repeat DUF1664 PF07889.10 001151067.1_53723001_3 - 1.3e-49 167.2 8.6 5.1e-49 165.2 4.4 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) DUF16 PF01519.14 001151067.1_53723001_3 - 1.4e-05 25.3 7.8 0.0012 19.1 5.1 3.0 3 0 0 3 3 3 1 Protein of unknown function DUF16 HemX PF04375.12 001151067.1_53723001_3 - 5.7e-05 22.4 5.4 6.7e-05 22.2 0.8 2.5 2 1 1 3 3 3 1 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_13 PF13166.4 001151067.1_53723001_3 - 0.00023 19.9 3.6 0.00023 19.9 3.6 1.3 2 0 0 2 2 2 1 AAA domain CLZ PF16526.3 001151067.1_53723001_3 - 0.00028 21.1 9.6 0.27 11.5 0.5 4.0 4 0 0 4 4 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels COG2 PF06148.9 001151067.1_53723001_3 - 0.0011 18.9 8.3 0.059 13.3 4.5 2.9 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Toxin_38 PF14866.4 001151067.1_53723001_3 - 0.011 15.9 0.2 0.035 14.3 0.2 1.9 1 0 0 1 1 1 0 Potassium channel toxin RTBV_P12 PF06361.9 001151067.1_53723001_3 - 0.011 15.9 0.7 0.47 10.7 0.1 2.4 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Cob_adeno_trans PF01923.16 001151067.1_53723001_3 - 0.02 14.9 2.3 2 8.4 2.2 2.6 2 1 0 2 2 2 0 Cobalamin adenosyltransferase LOH1CR12 PF10158.7 001151067.1_53723001_3 - 0.036 14.0 7.2 0.03 14.2 4.7 2.0 2 0 0 2 2 2 0 Tumour suppressor protein DUF677 PF05055.10 001151067.1_53723001_3 - 0.036 12.8 9.3 0.088 11.5 7.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF677) Baculo_PEP_C PF04513.10 001151067.1_53723001_3 - 0.037 13.9 6.7 1.7 8.5 2.4 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.10 001151067.1_53723001_3 - 0.04 13.2 1.1 0.19 10.9 0.1 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein HAP1_N PF04849.11 001151067.1_53723001_3 - 0.045 12.8 4.1 0.079 12.0 4.1 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region IFT57 PF10498.7 001151067.1_53723001_3 - 0.066 12.0 7.6 0.41 9.4 4.2 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF948 PF06103.9 001151067.1_53723001_3 - 0.076 13.1 7.3 2.1 8.5 1.2 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.9 001151067.1_53723001_3 - 0.15 12.5 4.1 1.7 9.1 3.1 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Apolipoprotein PF01442.16 001151067.1_53723001_3 - 0.19 11.5 10.9 2.6 7.8 7.7 3.0 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain MbeD_MobD PF04899.10 001151067.1_53723001_3 - 0.21 11.6 1.8 6.2 6.9 0.0 2.7 2 0 0 2 2 2 0 MbeD/MobD like COG5 PF10392.7 001151067.1_53723001_3 - 0.27 11.3 6.4 5.5 7.0 3.3 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Flagellin_N PF00669.18 001151067.1_53723001_3 - 0.36 10.8 9.5 0.51 10.3 0.1 2.6 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Filament PF00038.19 001151067.1_53723001_3 - 0.38 10.1 9.6 0.083 12.3 6.0 1.6 2 0 0 2 2 2 0 Intermediate filament protein Mod_r PF07200.11 001151067.1_53723001_3 - 0.47 10.4 7.6 0.4 10.7 4.6 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.7 001151067.1_53723001_3 - 0.49 10.6 11.2 1.4 9.2 0.2 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.6 001151067.1_53723001_3 - 0.53 9.4 7.8 1.4 8.0 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) RmuC PF02646.14 001151067.1_53723001_3 - 1.1 8.2 9.0 1.5 7.7 2.3 3.1 2 1 1 3 3 3 0 RmuC family DUF4795 PF16043.3 001151067.1_53723001_3 - 1.1 8.7 9.5 1.1 8.7 7.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.8 001151067.1_53723001_3 - 1.3 9.1 12.9 4 7.5 9.0 2.8 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.10 001151067.1_53723001_3 - 1.7 8.5 10.9 3.4 7.5 6.7 2.8 2 1 1 3 3 3 0 Laminin Domain II DUF2203 PF09969.7 001151067.1_53723001_3 - 1.7 9.3 5.8 35 5.0 2.8 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) NPV_P10 PF05531.10 001151067.1_53723001_3 - 1.8 9.0 13.5 1.2 9.5 0.2 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.4 001151067.1_53723001_3 - 2.4 8.5 10.7 3.1 8.2 6.9 2.7 3 0 0 3 3 3 0 Snapin/Pallidin KxDL PF10241.7 001151067.1_53723001_3 - 3.3 7.9 9.2 6.8 6.9 3.9 3.0 2 1 0 3 3 3 0 Uncharacterized conserved protein Spc7 PF08317.9 001151067.1_53723001_3 - 3.6 6.3 12.4 0.73 8.5 8.6 1.8 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF972 PF06156.11 001151067.1_53723001_3 - 4.4 7.8 7.7 30 5.2 5.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) XhlA PF10779.7 001151067.1_53723001_3 - 7.8 6.6 7.9 19 5.4 2.7 3.3 3 1 2 5 5 4 0 Haemolysin XhlA FGGY_N PF00370.19 001174850.1_53724001_2 - 3.5e-08 33.2 0.0 2.6e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.14 001174850.1_53724001_2 - 0.00078 19.1 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain PAE PF03283.11 001143427.1_53724001_1 - 8.2e-26 90.8 0.1 1.4e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Pectinacetylesterase PAE PF03283.11 001143427.1_53724001_2 - 1.4e-45 155.9 0.0 3.1e-44 151.4 0.0 2.1 2 0 0 2 2 2 2 Pectinacetylesterase PAE PF03283.11 001143427.1_53724001_3 - 3.8e-43 147.9 0.0 5.5e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase MATH PF00917.24 001151115.1_53724001_2 - 2.9e-16 59.5 0.0 5e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 MATH domain TMPIT PF07851.11 001151128.2_53723001_1 - 1.3e-96 323.6 0.0 1.7e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 TMPIT-like protein EF-hand_8 PF13833.4 001174944.1_53724001_1 - 1.3e-12 47.1 0.1 1.5e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.4 001174944.1_53724001_1 - 2e-09 37.6 0.7 1.6e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001174944.1_53724001_1 - 1.9e-08 33.1 0.0 2.3e-05 23.5 0.0 3.9 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.4 001174944.1_53724001_1 - 1e-06 27.9 0.5 7.9e-05 21.9 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.4 001174944.1_53724001_1 - 2.6e-06 26.8 0.3 0.00083 19.0 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.30 001174944.1_53724001_2 - 1.2e-07 30.6 1.9 0.00013 21.1 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.4 001174944.1_53724001_2 - 6.9e-06 25.2 1.2 0.00045 19.5 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.4 001174944.1_53724001_2 - 1.5e-05 24.4 1.8 0.0048 16.6 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.4 001174944.1_53724001_2 - 6e-05 22.6 2.2 0.0012 18.4 0.3 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.4 001174944.1_53724001_2 - 0.00015 22.0 0.0 0.027 14.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair DnaJ_C PF01556.16 001174952.1_53724001_1 - 5.2e-29 101.1 0.1 7.7e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 001174952.1_53724001_1 - 1.4e-24 85.9 3.3 2.2e-24 85.2 3.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.17 001174952.1_53724001_1 - 1.6e-10 41.1 18.7 2.8e-10 40.3 18.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.3 001174952.1_53724001_1 - 0.076 12.9 12.8 0.59 10.0 1.1 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Amidohydro_2 PF04909.12 001151214.2_53723001_2 - 1.4e-29 103.7 0.0 1.8e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase DNA_pol_B_palm PF14792.4 001151214.2_53723001_2 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm Acetyltransf_3 PF13302.5 001143539.1_53723001_3 - 1.3e-21 77.6 0.0 3.1e-21 76.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.23 001143539.1_53723001_3 - 1.5e-06 28.3 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.5 001143539.1_53723001_3 - 2.7e-05 24.3 0.2 4.3e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.4 001143539.1_53723001_3 - 0.00025 20.6 0.1 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.8 001143539.1_53723001_3 - 0.0018 18.0 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.5 001143539.1_53723001_3 - 0.012 15.9 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MutS_V PF00488.19 001174994.1_53726001_1 - 9.8e-33 113.7 0.2 5.6e-32 111.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain V RRM_1 PF00076.20 001143555.1_53723001_1 - 4e-36 122.5 0.0 4.3e-20 71.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001143555.1_53723001_1 - 0.0077 16.2 0.0 0.31 11.1 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif AKAP2_C PF15304.4 001143555.1_53723001_1 - 0.021 14.0 0.3 0.031 13.4 0.3 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus HATPase_c_3 PF13589.4 001328018.1_53725001_3 - 6.4e-16 58.3 0.1 1.3e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.24 001328018.1_53725001_3 - 8.2e-09 35.9 0.1 2.4e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PspA_IM30 PF04012.10 001328018.1_53725001_3 - 0.13 11.7 1.9 0.18 11.2 1.9 1.2 1 0 0 1 1 1 0 PspA/IM30 family Leu_zip PF15294.4 001328018.1_53725001_3 - 0.16 11.3 2.9 0.25 10.7 2.9 1.2 1 0 0 1 1 1 0 Leucine zipper BAG PF02179.14 001155872.2_53724001_1 - 7.9e-16 58.1 3.4 7.9e-16 58.1 3.4 1.6 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.21 001155872.2_53724001_1 - 9.7e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family PB1 PF00564.22 001155872.2_53724001_1 - 0.00048 19.9 0.1 0.00081 19.1 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Ubiquitin_2 PF14560.4 001155872.2_53724001_1 - 0.03 14.6 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain OPT PF03169.13 001175069.1_53725001_1 - 1.1e-139 466.8 35.2 1.3e-139 466.6 35.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein INSIG PF07281.10 001175069.1_53725001_1 - 0.21 11.1 4.3 0.73 9.3 0.2 2.7 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) Pkinase_Tyr PF07714.15 001175088.1_53725001_1 - 1.3e-45 155.6 0.0 1.8e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001175088.1_53725001_1 - 2.1e-43 148.4 0.0 3.1e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.21 001175088.1_53725001_1 - 0.11 12.2 0.0 0.39 10.5 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family GRA6 PF05084.11 001151405.2_53722001_1 - 0.1 12.5 1.1 0.16 11.9 1.1 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Dynamin_M PF01031.18 001175208.1_53724001_1 - 5.5e-61 206.2 0.0 7.8e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region GED PF02212.16 001175208.1_53724001_1 - 2.1e-22 79.0 0.0 9.9e-22 76.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain Dynamin_N PF00350.21 001175208.1_53724001_1 - 2.9e-21 76.1 0.1 4.9e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 Dynamin family RVT_1 PF00078.25 001175208.1_53724001_1 - 0.11 11.8 0.0 0.61 9.4 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) His_Phos_1 PF00300.20 001151579.1_53723001_1 - 1.7e-12 47.3 0.0 2.5e-05 23.9 0.0 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.23 001146859.1_53724001_1 - 3.6e-14 52.6 0.0 4.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001146859.1_53724001_1 - 2.8e-05 23.4 0.0 3.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4477 PF14780.4 001146859.1_53724001_2 - 3.7e-09 36.3 2.9 1.1e-08 34.8 2.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4477) Spc7 PF08317.9 001175304.1_53723001_1 - 0.013 14.3 0.1 0.017 13.8 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.11 001175304.1_53723001_1 - 0.088 13.1 0.3 0.15 12.4 0.3 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 V-SNARE PF05008.13 001175304.1_53723001_1 - 0.22 11.8 1.2 0.41 10.9 1.2 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus zf-RanBP PF00641.16 001175307.1_53726001_2 - 1.5e-13 49.6 23.4 2.6e-10 39.3 3.7 3.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others PHD PF00628.27 001175307.1_53726001_2 - 0.32 10.8 7.5 4 7.3 0.1 3.6 3 0 0 3 3 3 0 PHD-finger Stc1 PF12898.5 001175307.1_53726001_2 - 1.6 9.2 7.5 9.3 6.7 7.5 2.3 1 1 0 1 1 1 0 Stc1 domain zinc-ribbon_6 PF10005.7 001175307.1_53726001_2 - 6.5 7.4 10.1 3 8.5 0.3 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_10 PF10058.7 001175307.1_53726001_2 - 9.6 5.9 13.3 17 5.1 0.1 3.8 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Motile_Sperm PF00635.24 001175357.1_53724001_2 - 1.1e-29 102.3 0.6 2.2e-29 101.4 0.6 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF4201 PF13870.4 001175357.1_53724001_2 - 1.6e-05 24.5 2.6 2.6e-05 23.8 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) PI3K_P85_iSH2 PF16454.3 001175357.1_53724001_2 - 0.00031 20.2 1.1 0.00051 19.5 1.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SKA1 PF07160.10 001175357.1_53724001_2 - 0.022 14.5 1.0 0.04 13.6 1.0 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 She9_MDM33 PF05546.9 001175357.1_53724001_2 - 0.03 14.0 0.9 0.049 13.3 0.9 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family DUF972 PF06156.11 001175357.1_53724001_2 - 0.037 14.5 0.3 0.096 13.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4472 PF14739.4 001175357.1_53724001_2 - 0.052 14.1 2.5 0.11 13.1 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DUF4055 PF13264.4 001175357.1_53724001_2 - 0.061 13.4 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) GAS PF13851.4 001175357.1_53724001_2 - 0.064 12.5 3.3 0.097 11.9 3.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Muted PF14942.4 001175357.1_53724001_2 - 0.069 13.3 2.0 0.12 12.5 2.0 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein CENP-Q PF13094.4 001175357.1_53724001_2 - 0.073 13.1 1.9 0.13 12.3 1.9 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TraF_2 PF13729.4 001175357.1_53724001_2 - 0.11 11.7 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein IncA PF04156.12 001175357.1_53724001_2 - 0.12 12.0 3.0 0.22 11.2 3.0 1.3 1 0 0 1 1 1 0 IncA protein LPP PF04728.11 001175357.1_53724001_2 - 0.16 12.2 0.4 0.33 11.2 0.4 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper V-SNARE PF05008.13 001175357.1_53724001_2 - 0.3 11.4 2.9 0.56 10.5 2.9 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus SlyX PF04102.10 001175357.1_53724001_2 - 0.56 10.7 2.5 1.1 9.8 1.7 1.9 1 1 1 2 2 2 0 SlyX zf-DHHC PF01529.18 001175419.2_53725001_3 - 7e-29 100.5 10.0 7e-29 100.5 10.0 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase FAP PF07174.9 001151732.2_53722001_3 - 1.5 8.1 14.0 2 7.7 14.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PP2C PF00481.19 001156251.1_53724001_1 - 5.6e-40 137.5 0.0 8.7e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001156251.1_53724001_1 - 1.1e-05 25.0 0.1 2.1e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.10 001156251.1_53724001_1 - 0.0035 17.2 0.0 0.05 13.4 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Remorin_C PF03763.11 001156270.1_53723001_1 - 6e-33 112.8 24.6 8.9e-33 112.3 24.6 1.3 1 0 0 1 1 1 1 Remorin, C-terminal region WD40 PF00400.30 001329466.1_53726001_1 - 9.9e-11 41.9 14.0 0.033 14.9 1.8 7.6 8 0 0 8 8 8 4 WD domain, G-beta repeat PD40 PF07676.10 001329466.1_53726001_1 - 0.014 15.2 0.1 5.3 7.0 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.3 001329466.1_53726001_1 - 0.089 11.6 0.0 7.1 5.4 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FtsK_SpoIIIE_N PF12538.6 001329466.1_53726001_1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA transporter Lipase_GDSL PF00657.20 001112330.2_53724001_1 - 1.2e-26 93.9 0.0 1.5e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WRKY PF03106.13 001175743.1_53726001_1 - 3.7e-48 161.6 18.0 2e-24 85.6 4.6 2.3 2 0 0 2 2 2 2 WRKY DNA -binding domain FKBP_C PF00254.26 001147156.1_53723001_1 - 1.4e-20 73.3 0.0 2.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4813 PF16072.3 001348293.1_53725001_1 - 0.37 10.3 7.2 0.48 9.9 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) NERD PF08378.9 001152060.1_53722001_2 - 2.5e-05 24.6 0.0 5.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Nuclease-related domain zf-RING_2 PF13639.4 001348973.1_53723001_1 - 4.3e-13 49.2 5.9 4.3e-13 49.2 5.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.4 001348973.1_53723001_1 - 4.1e-10 39.2 5.9 4.1e-10 39.2 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.4 001348973.1_53723001_1 - 5.8e-10 39.1 2.3 5.8e-10 39.1 2.3 3.5 4 0 0 4 4 4 1 zinc-ribbon zf-RING_11 PF17123.3 001348973.1_53723001_1 - 1.7e-08 33.9 0.5 5.8e-08 32.2 0.5 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.23 001348973.1_53723001_1 - 1.7e-07 30.8 12.6 2.4e-07 30.4 3.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001348973.1_53723001_1 - 9.6e-06 25.4 1.5 2.5e-05 24.1 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.4 001348973.1_53723001_1 - 2.7e-05 23.8 10.7 0.00015 21.4 3.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001348973.1_53723001_1 - 4.6e-05 23.5 10.8 4.6e-05 23.5 10.8 2.2 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.4 001348973.1_53723001_1 - 0.00055 19.7 3.5 0.00055 19.7 3.5 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001348973.1_53723001_1 - 0.002 18.0 6.6 0.002 18.0 6.6 2.0 2 0 0 2 2 1 1 RING-type zinc-finger Rad50_zn_hook PF04423.12 001348973.1_53723001_1 - 0.013 15.2 5.1 0.23 11.2 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif Prok-RING_4 PF14447.4 001348973.1_53723001_1 - 0.59 9.9 16.5 0.62 9.8 10.2 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.10 001348973.1_53723001_1 - 3.5 7.9 10.2 14 5.9 0.2 3.5 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.4 001348973.1_53723001_1 - 4 7.1 11.8 1.7 8.3 3.8 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.4 001348973.1_53723001_1 - 4.3 7.2 9.8 17 5.3 0.3 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.9 001348973.1_53723001_1 - 7.8 6.8 11.8 0.087 13.0 2.9 2.3 2 1 0 2 2 2 0 RING-like domain FBD PF08387.8 001175795.1_53724001_1 - 9e-12 44.5 1.6 2.6e-10 39.9 0.0 2.9 2 1 0 2 2 2 1 FBD F-box-like PF12937.5 001175795.1_53724001_1 - 0.00041 20.0 0.5 0.00041 20.0 0.5 2.4 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.11 001175795.1_53724001_1 - 0.0014 19.1 0.0 0.012 16.1 0.0 2.8 2 0 0 2 2 2 1 Leucine Rich Repeat F-box PF00646.31 001175795.1_53724001_1 - 0.015 15.1 0.3 0.04 13.7 0.3 1.8 1 0 0 1 1 1 0 F-box domain E1-E2_ATPase PF00122.18 001175803.1_53727001_1 - 5.2e-61 205.6 0.5 5.2e-61 205.6 0.5 3.4 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.24 001175803.1_53727001_1 - 3.4e-19 69.8 0.1 9.5e-19 68.4 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 001175803.1_53727001_1 - 6.3e-16 57.7 0.1 2.1e-15 56.0 0.1 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.4 001175803.1_53727001_1 - 0.0001 22.2 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.10 001175803.1_53727001_1 - 0.00048 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase adh_short PF00106.23 001152117.1_53723001_2 - 8e-36 123.2 0.0 1.2e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001152117.1_53723001_2 - 5.7e-22 78.3 0.4 8.1e-22 77.8 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001152117.1_53723001_2 - 1.5e-05 24.9 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.17 001152117.1_53723001_2 - 0.0035 16.6 0.1 0.0065 15.7 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.13 001152117.1_53723001_2 - 0.058 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Adeno_E3_CR2 PF02439.13 001152117.1_53723001_2 - 1.4 8.6 7.3 2.8 7.6 7.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ribosomal_S25 PF03297.13 001294291.1_53722001_3 - 1.4e-41 140.7 1.0 2e-41 140.2 1.0 1.2 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.4 001294291.1_53722001_3 - 0.0038 16.6 0.1 0.0053 16.2 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF2890 PF11081.6 001294291.1_53722001_3 - 0.0053 16.7 0.5 0.0064 16.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) MarR_2 PF12802.5 001294291.1_53722001_3 - 0.0098 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 1 MarR family AIPR PF10592.7 001294291.1_53722001_3 - 0.024 14.1 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 AIPR protein DUF239 PF03080.13 001152205.1_53725001_2 - 2.4e-87 291.9 0.2 3.3e-87 291.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF239) DUF4409 PF14365.4 001152205.1_53725001_2 - 6e-39 133.0 0.0 1.1e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4409) Med3 PF11593.6 001152205.1_53725001_2 - 8.9 5.2 5.6 12 4.9 1.5 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal TRP PF06011.10 001318964.1_53728001_1 - 0.68 8.4 9.2 3.2 6.2 0.7 3.0 3 0 0 3 3 3 0 Transient receptor potential (TRP) ion channel DGF-1_C PF11040.6 001318964.1_53728001_1 - 3.5 7.6 5.0 1.1 9.2 0.1 2.7 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Epimerase PF01370.19 001347889.1_53723001_1 - 1.5e-31 109.5 0.0 2.2e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001347889.1_53723001_1 - 3.1e-20 72.2 0.0 4.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001347889.1_53723001_1 - 8.8e-19 68.0 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.10 001347889.1_53723001_1 - 2.2e-18 66.2 0.0 2e-14 53.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.3 001347889.1_53723001_1 - 4.6e-17 62.2 0.0 1.6e-16 60.4 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.11 001347889.1_53723001_1 - 1e-10 41.4 0.1 1.5e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.13 001347889.1_53723001_1 - 4.2e-07 29.3 0.2 2.7e-06 26.6 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.15 001347889.1_53723001_1 - 3.3e-06 26.3 0.0 4.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.23 001347889.1_53723001_1 - 0.064 12.6 0.2 0.3 10.4 0.1 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.22 001347889.1_53723001_1 - 0.09 13.1 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.17 001175995.1_53724001_2 - 4.1e-70 235.8 0.0 5.1e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.19 001175995.1_53724001_2 - 6.5e-24 84.6 0.0 9e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.10 001175995.1_53724001_2 - 8.7e-19 67.5 0.0 1.4e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.4 001175995.1_53724001_2 - 3.2e-12 46.6 0.0 6.7e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.3 001175995.1_53724001_2 - 4.2e-11 42.7 0.0 1.3e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.15 001175995.1_53724001_2 - 5.9e-10 38.6 0.0 9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.13 001175995.1_53724001_2 - 3.3e-08 32.9 0.0 3.3e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.11 001175995.1_53724001_2 - 0.00086 18.8 0.1 0.0012 18.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Pkinase PF00069.23 001176109.1_53726001_2 - 5.5e-19 68.4 0.0 7.6e-09 35.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.15 001176109.1_53726001_2 - 6e-18 64.9 0.0 1.2e-08 34.4 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.5 001176109.1_53726001_2 - 1.8e-09 37.5 23.2 0.025 14.9 2.6 6.9 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001176109.1_53726001_2 - 1.3e-06 28.0 14.1 0.004 16.8 2.2 4.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.31 001176109.1_53726001_2 - 0.00011 22.0 23.3 1.4 9.5 0.3 8.6 8 0 0 8 8 8 3 Leucine Rich Repeat zf-C3HC4_2 PF13923.4 001176194.1_53724001_1 - 7.4e-12 44.8 8.2 1.3e-11 44.0 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001176194.1_53724001_1 - 1.2e-08 34.5 8.5 2.2e-08 33.7 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001176194.1_53724001_1 - 2.4e-07 30.8 8.8 4.5e-07 29.9 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.4 001176194.1_53724001_1 - 3.3e-05 23.5 12.6 5.3e-05 22.9 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001176194.1_53724001_1 - 7.9e-05 22.5 7.4 0.00019 21.2 7.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001176194.1_53724001_1 - 0.00023 20.9 8.3 0.00066 19.5 8.4 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.4 001176194.1_53724001_1 - 0.0019 18.2 6.7 0.0041 17.1 6.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.4 001176194.1_53724001_1 - 0.013 15.1 9.0 0.048 13.3 9.1 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.4 001176194.1_53724001_1 - 0.031 14.2 4.8 0.077 13.0 4.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.4 001176194.1_53724001_1 - 0.041 13.6 6.9 0.075 12.8 6.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.5 001176194.1_53724001_1 - 0.059 13.5 7.1 0.24 11.6 7.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001176194.1_53724001_1 - 0.098 12.3 4.2 0.22 11.2 4.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_5 PF17121.3 001176194.1_53724001_1 - 0.16 11.7 9.1 0.46 10.3 9.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001176194.1_53724001_1 - 0.18 11.6 12.5 2.2 8.1 12.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.3 001176194.1_53724001_1 - 0.23 11.5 7.9 0.53 10.3 7.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.6 001176194.1_53724001_1 - 0.38 10.5 5.9 0.4 10.4 4.3 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PGM_PMM_II PF02879.14 001176195.1_53724001_3 - 6.4e-22 78.0 0.0 1.2e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.14 001176195.1_53724001_3 - 2.5e-09 37.2 0.3 4.7e-09 36.3 0.3 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.14 001176195.1_53724001_3 - 1.6e-06 27.8 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I MFMR PF07777.9 001156967.1_53725001_1 - 9.8e-27 93.2 19.2 9.8e-27 93.2 19.2 2.7 3 1 0 3 3 1 1 G-box binding protein MFMR bZIP_1 PF00170.19 001156967.1_53725001_1 - 1.3e-18 66.7 30.9 1.2e-17 63.6 19.4 2.3 1 1 1 2 2 2 2 bZIP transcription factor MFMR_assoc PF16596.3 001156967.1_53725001_1 - 2.4e-17 63.5 13.5 6.1e-17 62.2 13.5 1.7 1 0 0 1 1 1 1 Disordered region downstream of MFMR bZIP_2 PF07716.13 001156967.1_53725001_1 - 2.5e-08 33.7 22.2 5.8e-07 29.4 18.2 2.5 1 1 1 2 2 2 2 Basic region leucine zipper GIT_CC PF16559.3 001156967.1_53725001_1 - 6.3e-05 22.8 1.5 0.00011 22.0 1.5 1.4 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor ADIP PF11559.6 001156967.1_53725001_1 - 0.0034 17.3 14.6 0.0056 16.7 14.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding bZIP_Maf PF03131.15 001156967.1_53725001_1 - 0.0042 17.4 10.7 0.0075 16.6 10.7 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.10 001156967.1_53725001_1 - 0.017 15.4 5.4 0.017 15.4 5.4 1.9 1 1 1 2 2 2 0 Cell division protein ZapB TPR_MLP1_2 PF07926.10 001156967.1_53725001_1 - 0.02 14.8 12.5 0.032 14.2 12.5 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.9 001156967.1_53725001_1 - 0.049 13.7 0.8 0.11 12.6 0.8 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Cluap1 PF10234.7 001156967.1_53725001_1 - 0.11 11.8 7.3 0.16 11.2 7.3 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 APG6 PF04111.10 001156967.1_53725001_1 - 0.14 11.4 12.4 0.2 10.9 12.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 JIP_LZII PF16471.3 001156967.1_53725001_1 - 0.22 11.6 5.0 0.43 10.7 3.4 2.0 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II UPF0449 PF15136.4 001156967.1_53725001_1 - 0.26 11.6 5.6 0.51 10.7 5.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 HALZ PF02183.16 001156967.1_53725001_1 - 0.26 11.4 11.0 0.34 11.0 5.0 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper HIP1_clath_bdg PF16515.3 001156967.1_53725001_1 - 1.8 9.1 14.1 3.1 8.3 14.1 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF972 PF06156.11 001156967.1_53725001_1 - 2.2 8.8 5.2 4.6 7.8 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Jnk-SapK_ap_N PF09744.7 001156967.1_53725001_1 - 2.5 8.2 13.1 3.8 7.6 13.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DivIC PF04977.13 001156967.1_53725001_1 - 5 6.8 8.3 0.38 10.4 2.4 1.9 1 1 1 2 2 2 0 Septum formation initiator RAP1 PF07218.9 001156967.1_53725001_1 - 8.4 4.4 15.6 14 3.7 15.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ustilago_mating PF05722.10 001152674.1_53725001_2 - 1.1 8.5 7.4 2.3 7.6 7.4 1.4 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Exo_endo_phos PF03372.21 001152676.1_53725001_1 - 8.7e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.3 001152676.1_53725001_1 - 5.6e-08 32.8 5.8 1.1e-07 31.9 5.8 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.16 001152676.1_53725001_1 - 0.031 14.2 4.6 0.066 13.2 4.6 1.5 1 0 0 1 1 1 0 MYND finger Cu_bind_like PF02298.15 001157032.2_53722001_1 - 2.4e-18 65.8 0.0 3.4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Plastocyanin-like domain SAD_SRA PF02182.15 001319048.1_53725001_1 - 7.5e-47 158.6 0.2 1.2e-46 158.0 0.2 1.3 1 0 0 1 1 1 1 SAD/SRA domain Pre-SET PF05033.14 001319048.1_53725001_1 - 5.1e-20 72.0 2.4 2e-19 70.1 1.3 2.2 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.26 001319048.1_53725001_1 - 1.4e-16 61.2 0.1 1.1e-15 58.3 0.0 2.4 2 0 0 2 2 2 1 SET domain Aa_trans PF01490.16 001176365.1_53724001_1 - 1.3e-60 205.1 28.3 1.6e-60 204.8 28.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC_tran PF00005.25 001136858.1_53724001_1 - 6.2e-27 94.6 1.2 1.1e-26 93.8 0.0 2.0 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.4 001136858.1_53724001_1 - 1.3e-07 31.6 0.4 0.0044 16.7 0.2 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.4 001136858.1_53724001_1 - 6e-06 25.8 0.3 1.3e-05 24.7 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.14 001136858.1_53724001_1 - 0.00011 22.0 0.1 0.00011 22.0 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_23 PF13476.4 001136858.1_53724001_1 - 0.0004 20.8 1.3 0.00097 19.6 0.1 2.1 2 1 1 3 3 2 1 AAA domain SMC_N PF02463.17 001136858.1_53724001_1 - 0.00087 18.7 0.0 0.055 12.8 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.4 001136858.1_53724001_1 - 0.0012 18.4 0.1 0.0039 16.7 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.4 001136858.1_53724001_1 - 0.0043 17.3 0.6 0.0072 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.10 001136858.1_53724001_1 - 0.019 14.8 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.21 001136858.1_53724001_1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_ATPase PF09818.7 001136858.1_53724001_1 - 0.027 13.1 0.2 0.046 12.4 0.2 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class ArgK PF03308.14 001136858.1_53724001_1 - 0.034 13.0 0.3 0.062 12.1 0.3 1.3 1 0 0 1 1 1 0 ArgK protein AAA_24 PF13479.4 001136858.1_53724001_1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001136858.1_53724001_1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.13 001136858.1_53724001_1 - 0.12 12.2 0.1 17 5.1 0.0 2.3 2 0 0 2 2 2 0 NTPase PRK PF00485.16 001136858.1_53724001_1 - 0.19 11.3 0.6 0.8 9.3 0.1 2.3 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Sec23_helical PF04815.13 001136891.1_53723001_1 - 3.6e-24 84.4 0.0 2.3e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.10 001136891.1_53723001_1 - 0.00091 19.8 0.1 0.0017 18.9 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.13 001136891.1_53723001_3 - 3.2e-12 46.4 0.0 1.7e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.13 001136891.1_53723001_3 - 2.9e-10 39.9 0.4 8e-10 38.5 0.4 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.10 001136891.1_53723001_3 - 6.9e-07 29.8 0.0 1.1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain VWA PF00092.26 001136891.1_53723001_3 - 0.094 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain NAM PF02365.13 001317848.1_53725001_3 - 1.1e-07 32.5 0.4 2.2e-07 31.5 0.4 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein Adipogenin PF15202.4 001317848.1_53725001_3 - 0.69 9.8 2.8 1.6 8.6 0.5 2.6 2 0 0 2 2 2 0 Adipogenin NAM PF02365.13 001152864.1_53725001_1 - 2e-29 102.1 0.3 3.9e-29 101.2 0.3 1.5 1 0 0 1 1 1 1 No apical meristem (NAM) protein DUF659 PF04937.13 001152881.1_53726001_2 - 4.9e-10 39.3 0.0 7.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SRF-TF PF00319.16 001152881.1_53726001_3 - 8.8e-22 76.2 0.0 1.7e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.15 001152881.1_53726001_3 - 7.6e-11 41.9 0.8 1.9e-10 40.6 0.9 1.5 2 0 0 2 2 2 1 K-box region DUF1618 PF07762.12 001152885.1_53726001_3 - 1e-12 48.8 0.0 2.6e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1618) Pkinase PF00069.23 001176632.1_53726001_2 - 1.1e-23 83.8 0.0 1.6e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001176632.1_53726001_2 - 1.7e-18 66.7 0.0 2.5e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.15 001176632.1_53726001_3 - 4.2e-12 45.8 0.0 6.8e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001176632.1_53726001_3 - 6.1e-10 38.8 0.0 9.3e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Usp PF00582.24 001176632.1_53726001_3 - 0.00019 21.9 0.1 0.00032 21.1 0.1 1.3 1 0 0 1 1 1 1 Universal stress protein family vATP-synt_AC39 PF01992.14 001153021.1_53724001_2 - 1e-56 192.7 1.8 1.3e-56 192.4 1.8 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit vATP-synt_AC39 PF01992.14 001153021.1_53724001_3 - 1.4e-50 172.5 0.1 1.9e-50 172.1 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Epimerase PF01370.19 001157399.1_53724001_2 - 1e-19 70.8 0.0 2.1e-19 69.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.4 001157399.1_53724001_2 - 1.1e-11 44.8 0.7 1.8e-11 44.1 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.17 001157399.1_53724001_2 - 2.8e-10 39.5 0.0 4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.3 001157399.1_53724001_2 - 1e-08 34.9 0.0 3.8e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.11 001157399.1_53724001_2 - 1.9e-06 27.5 0.1 4e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.10 001157399.1_53724001_2 - 3.3e-06 26.3 0.3 1.9e-05 23.8 0.3 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.23 001157399.1_53724001_2 - 5.8e-06 25.8 0.1 8.9e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.13 001157399.1_53724001_2 - 7.9e-05 21.8 0.0 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.8 001157399.1_53724001_2 - 0.0077 16.0 0.4 0.013 15.3 0.4 1.3 1 0 0 1 1 1 1 KR domain DUF1731 PF08338.9 001157399.1_53724001_2 - 0.091 12.5 0.0 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) PLD_C PF12357.6 001153087.1_53726001_3 - 2.9e-30 103.8 0.0 5.2e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.20 001153087.1_53726001_3 - 1.2e-21 75.8 0.4 4.4e-11 42.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif C2 PF00168.28 001153087.1_53726001_3 - 7.6e-13 48.5 0.0 1.8e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain PLDc_2 PF13091.4 001153087.1_53726001_3 - 3.8e-10 39.6 0.0 9.6e-07 28.6 0.1 3.3 2 2 0 2 2 2 2 PLD-like domain EamA PF00892.18 001176762.1_53723001_2 - 4.8e-22 78.5 30.4 1.1e-15 57.9 13.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.12 001176762.1_53723001_2 - 0.00075 18.6 0.2 0.0015 17.5 0.2 1.4 1 0 0 1 1 1 1 Magnesium transporter NIPA CRT-like PF08627.8 001176762.1_53723001_2 - 0.017 14.0 0.1 0.036 12.9 0.1 1.4 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like OST3_OST6 PF04756.11 001176762.1_53723001_2 - 0.17 11.1 0.4 7.5 5.7 0.2 2.2 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family SLC35F PF06027.10 001176762.1_53723001_2 - 0.27 10.6 4.1 1 8.7 0.4 2.1 1 1 1 2 2 2 0 Solute carrier family 35 AOX PF01786.15 001148083.2_53723001_1 - 7.6e-27 94.2 4.0 5.5e-17 61.9 0.7 2.1 2 0 0 2 2 2 2 Alternative oxidase COQ7 PF03232.11 001148083.2_53723001_1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Terpene_synth_C PF03936.14 001148090.1_53724001_2 - 4e-96 321.4 5.4 4.2e-96 321.3 3.2 1.8 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Terpene_synth PF01397.19 001148090.1_53724001_2 - 5e-48 163.2 0.0 8.2e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain ECH_2 PF16113.3 001148090.1_53724001_2 - 0.019 14.3 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase SpoVAD PF07451.9 001148090.1_53724001_2 - 0.049 12.2 0.0 0.075 11.6 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF3368 PF11848.6 001148090.1_53724001_2 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Pkinase PF00069.23 001148104.1_53724001_2 - 8.5e-59 198.9 0.0 1.1e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001148104.1_53724001_2 - 3.5e-26 91.9 0.0 4.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001148104.1_53724001_2 - 0.0002 20.6 0.1 0.072 12.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.18 001148104.1_53724001_2 - 0.00028 20.4 0.2 0.00041 19.9 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.21 001148104.1_53724001_2 - 0.0027 17.5 0.2 0.063 13.1 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.12 001148104.1_53724001_2 - 0.02 14.1 0.4 0.03 13.5 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.9 001148104.1_53724001_2 - 0.1 11.4 3.6 0.028 13.3 0.4 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.23 001148104.1_53724001_3 - 0.0088 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1336 PF07059.10 001176871.2_53723001_2 - 8.1e-11 42.2 0.1 1.4e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) DUF1336 PF07059.10 001176871.2_53723001_3 - 3.9e-07 30.2 0.0 1.9e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1336) GMC_oxred_N PF00732.17 001153219.1_53725001_1 - 2.7e-33 115.5 0.0 4.9e-32 111.3 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.11 001153219.1_53725001_1 - 4.8e-29 101.6 0.0 5.1e-28 98.3 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.22 001153219.1_53725001_1 - 6.6e-05 22.6 0.1 0.012 15.1 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.4 001153219.1_53725001_1 - 0.0012 18.9 0.0 0.0036 17.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.10 001153219.1_53725001_1 - 0.0093 14.9 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.22 001153219.1_53725001_1 - 0.014 14.4 0.3 0.47 9.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.17 001153219.1_53725001_1 - 0.03 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.12 001153219.1_53725001_1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.25 001153219.1_53725001_1 - 0.18 12.3 0.0 2.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_deac_1 PF01522.19 001176926.1_53723001_3 - 0.12 12.2 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide deacetylase GTP_EFTU PF00009.25 001323371.1_53724001_1 - 4.6e-53 179.5 0.0 8.1e-53 178.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001323371.1_53724001_1 - 1.6e-38 131.3 0.1 4e-38 130.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001323371.1_53724001_1 - 1.3e-14 54.2 1.0 2.2e-14 53.5 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001323371.1_53724001_1 - 0.0018 18.2 0.1 0.0063 16.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.8 001323371.1_53724001_1 - 0.021 14.1 0.1 0.28 10.4 0.0 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.4 001323371.1_53724001_1 - 0.029 14.2 2.1 0.033 14.0 0.1 2.1 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.16 001323371.1_53724001_1 - 0.074 13.0 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain AAA_22 PF13401.4 001323371.1_53724001_1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain EF-hand_7 PF13499.4 001137260.2_53724001_3 - 1.5e-06 28.4 0.0 1.5e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.4 001137260.2_53724001_3 - 1.7e-05 23.9 0.6 1.7e-05 23.9 0.6 2.8 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.4 001137260.2_53724001_3 - 2e-05 24.0 0.7 0.005 16.5 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.30 001137260.2_53724001_3 - 5.9e-05 22.2 1.2 0.00069 18.9 0.1 3.2 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.4 001137260.2_53724001_3 - 0.03 13.9 0.1 0.5 10.0 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair FPN1 PF06963.10 001153299.1_53723001_3 - 1.9e-112 375.9 15.7 2.2e-112 375.7 15.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_5 PF05631.12 001137285.1_53726001_1 - 4.1e-141 469.8 10.0 8.5e-110 366.8 4.4 2.1 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_5 PF05631.12 001137285.1_53726001_3 - 1.3e-49 168.9 2.9 1.7e-49 168.5 2.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Lipase_GDSL PF00657.20 001148347.1_53723001_2 - 8e-25 87.9 0.0 9.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RIO1 PF01163.20 001153436.1_53725001_3 - 8.6e-50 168.8 0.1 8.6e-50 168.8 0.1 2.3 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.9 001153436.1_53725001_3 - 8.8e-35 118.6 0.5 1.6e-34 117.8 0.5 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.21 001153436.1_53725001_3 - 4.9e-09 36.3 1.4 3.4e-05 23.7 0.3 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.12 001153436.1_53725001_3 - 4.2e-05 22.9 0.9 0.17 11.0 0.0 2.6 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4604 PF15377.4 001153436.1_53725001_3 - 0.0056 17.0 19.9 0.0092 16.3 14.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) CDC45 PF02724.12 001153436.1_53725001_3 - 7.6 4.6 13.2 0.061 11.5 2.9 2.2 2 0 0 2 2 2 0 CDC45-like protein DPM3 PF08285.9 001148415.1_53723001_2 - 3.6 7.7 6.9 1 9.4 0.6 2.7 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) WW PF00397.24 001153587.1_53725001_1 - 2.6e-26 91.1 13.5 2e-13 49.9 1.1 2.6 2 0 0 2 2 2 2 WW domain Hydrolase_2 PF07486.10 001153587.1_53725001_1 - 0.49 11.1 0.0 0.49 11.1 0.0 2.7 2 1 1 3 3 3 0 Cell Wall Hydrolase TPX2 PF06886.9 001137520.1_53724001_2 - 3.9e-21 74.9 10.2 3.9e-21 74.9 10.2 2.4 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) ESM4 PF15952.3 001137520.1_53724001_2 - 0.74 10.1 5.5 1.4 9.2 5.5 1.4 1 0 0 1 1 1 0 Enhancer of split M4 family HSF_DNA-bind PF00447.15 001153656.1_53725001_1 - 6.6e-28 97.0 0.1 1.2e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding APG6 PF04111.10 001153656.1_53725001_1 - 0.012 14.9 0.9 0.018 14.3 0.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Macoilin PF09726.7 001153656.1_53725001_1 - 0.38 9.1 4.2 0.52 8.7 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Glyco_transf_90 PF05686.10 001148576.1_53724001_3 - 9.1e-167 554.8 0.0 1.1e-166 554.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 UPF0233 PF06781.10 001196178.1_53723001_1 - 0.47 10.4 1.9 1.1 9.2 1.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) LRR_6 PF13516.4 001196178.1_53723001_2 - 0.00027 20.6 0.1 0.27 11.3 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeat ADH_N PF08240.10 001137801.1_53723001_1 - 3.7e-24 84.6 4.3 3.7e-24 84.6 4.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.24 001137801.1_53723001_1 - 1.9e-16 60.0 0.0 3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.17 001137801.1_53723001_1 - 4.4e-05 22.8 0.0 7.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.13 001137801.1_53723001_1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase START PF01852.17 001137819.1_53723001_2 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 START domain FMN_red PF03358.13 001153834.1_53723001_2 - 1.1e-10 41.3 0.1 1.8e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.15 001153834.1_53723001_2 - 8.9e-06 25.4 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.23 001153834.1_53723001_2 - 0.001 19.2 0.1 0.0026 17.8 0.1 1.8 1 1 1 2 2 2 1 Flavodoxin HLH PF00010.24 001347873.1_53724001_3 - 5e-10 39.1 0.7 8.9e-10 38.3 0.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bHLH-MYC_N PF14215.4 001347873.1_53724001_3 - 9.4e-10 38.8 0.3 0.0011 19.1 0.0 2.6 3 0 0 3 3 3 2 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.24 001347874.1_53725001_3 - 5.7e-10 38.9 0.7 1e-09 38.1 0.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bHLH-MYC_N PF14215.4 001347874.1_53725001_3 - 1.3e-09 38.4 0.3 0.0013 18.9 0.0 2.6 3 0 0 3 3 3 2 bHLH-MYC and R2R3-MYB transcription factors N-terminal Rieske_2 PF13806.4 001158194.2_53723001_3 - 2.7e-22 78.5 0.0 4e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.24 001158194.2_53723001_3 - 0.0023 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FrhB_FdhB_C PF04432.11 001137952.1_53724001_2 - 6.3e-29 100.7 0.0 1.1e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.11 001137952.1_53724001_2 - 8.5e-25 86.6 0.0 1.5e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term zf-B_box PF00643.22 001158251.1_53723001_1 - 1.9e-12 46.9 10.1 5.2e-06 26.4 0.8 2.3 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.3 001158251.1_53723001_1 - 2.8e-05 24.1 11.9 0.0047 17.0 0.8 2.4 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain PHD PF00628.27 001158251.1_53723001_1 - 1.9 8.3 18.3 0.31 10.8 2.5 2.7 2 1 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.4 001158251.1_53723001_1 - 3.8 7.3 15.9 0.15 11.9 2.8 2.1 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon DUF2318 PF10080.7 001158251.1_53723001_1 - 4.6 7.3 15.9 0.32 11.0 1.8 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Toxin_12 PF07740.10 001158251.1_53723001_2 - 1.6 9.4 8.6 0.15 12.6 3.6 2.0 2 0 0 2 2 2 0 Ion channel inhibitory toxin DUF3522 PF12036.6 001196671.1_53724001_3 - 1.4e-51 175.3 15.9 2e-51 174.8 15.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF1883 PF08980.8 001196671.1_53724001_3 - 0.071 12.9 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) Alg14 PF08660.9 001158317.2_53722001_2 - 4.5e-62 209.0 0.1 5.8e-62 208.6 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TFIIA_gamma_C PF02751.12 001158317.2_53722001_3 - 4.7e-09 36.0 0.0 8.2e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit ABC2_membrane PF01061.22 001349037.1_53723001_1 - 0.00042 19.7 3.1 0.00042 19.7 3.1 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane PF01061.22 001349037.1_53723001_3 - 6.6e-43 146.4 16.0 9.2e-43 146.0 16.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter DUF2070 PF09843.7 001349037.1_53723001_3 - 9.1 4.3 9.5 11 4.0 9.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PTR2 PF00854.19 001154127.1_53725001_2 - 2.8e-65 220.6 10.2 5.6e-38 130.7 1.5 2.1 2 0 0 2 2 2 2 POT family MFS_1 PF07690.14 001154127.1_53725001_2 - 0.00052 18.9 44.9 0.064 12.0 25.1 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Prominin PF05478.9 001154127.1_53725001_2 - 0.2 9.4 0.2 0.29 8.9 0.2 1.1 1 0 0 1 1 1 0 Prominin Gate PF07670.12 001154127.1_53725001_2 - 8.2 6.6 8.8 2.1 8.5 5.1 2.1 2 0 0 2 2 2 0 Nucleoside recognition zf-C3HC4_3 PF13920.4 001154992.2_53723001_1 - 2.9e-07 30.1 8.1 5e-07 29.4 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001154992.2_53723001_1 - 0.0012 18.5 10.0 0.0023 17.6 10.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF3037 PF11236.6 001154992.2_53723001_1 - 0.0045 17.3 1.4 0.0073 16.6 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3037) DUF484 PF04340.10 001154992.2_53723001_1 - 0.055 13.0 3.1 0.085 12.4 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF484 GreA_GreB_N PF03449.13 001154992.2_53723001_1 - 3.5 7.7 7.9 6.2 6.9 7.9 1.3 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal GATA PF00320.25 001154197.2_53724001_1 - 1e-15 56.9 3.9 1.8e-15 56.1 3.9 1.4 1 0 0 1 1 1 1 GATA zinc finger Pkinase PF00069.23 001154321.1_53727001_3 - 3.6e-46 157.5 0.0 6.4e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001154321.1_53727001_3 - 7.7e-43 146.5 0.0 1.1e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GUB_WAK_bind PF13947.4 001154321.1_53727001_3 - 2.9e-31 108.3 3.7 1.1e-14 54.9 0.3 2.9 2 0 0 2 2 2 2 Wall-associated receptor kinase galacturonan-binding DUF1049 PF06305.9 001154321.1_53727001_3 - 0.0099 15.6 0.4 0.025 14.3 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) FXa_inhibition PF14670.4 001154321.1_53727001_3 - 8.9 6.6 14.2 10 6.4 2.3 3.2 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Glyco_hydro_79n PF03662.12 001158611.1_53725001_1 - 4.7e-146 485.6 0.0 5.9e-146 485.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain zf-RING-like PF08746.9 001158655.1_53723001_1 - 0.23 11.7 2.5 0.49 10.6 2.5 1.5 1 0 0 1 1 1 0 RING-like domain PBD PF00786.26 001158655.1_53723001_2 - 5.7e-10 39.3 0.2 1e-09 38.5 0.2 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain Myb_DNA-binding PF00249.29 001254930.1_53723001_1 - 4.9e-31 106.5 0.2 6.2e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001254930.1_53723001_1 - 5.5e-18 64.8 0.2 3e-12 46.5 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Menin PF05053.11 001254930.1_53723001_1 - 0.073 11.3 0.5 0.13 10.4 0.5 1.3 1 0 0 1 1 1 0 Menin ABC_tran PF00005.25 001279865.1_53723001_2 - 5e-28 98.2 0.0 7.8e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.4 001279865.1_53723001_2 - 0.0034 16.9 0.3 0.0067 16.0 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.4 001279865.1_53723001_2 - 0.0064 16.2 0.1 0.054 13.2 0.1 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.4 001279865.1_53723001_2 - 0.0097 16.3 0.6 0.015 15.7 0.6 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.21 001279865.1_53723001_2 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.15 001279865.1_53723001_2 - 0.061 13.2 0.5 0.2 11.5 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.4 001279865.1_53723001_2 - 0.077 13.1 0.1 0.34 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.14 001279865.1_53723001_2 - 0.14 11.9 0.2 0.24 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HMGL-like PF00682.17 001154490.1_53725001_2 - 7.2e-89 297.7 0.3 1.3e-88 296.9 0.1 1.5 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.8 001154490.1_53725001_2 - 1.9e-36 124.7 0.2 3.4e-36 123.9 0.2 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain F-box-like PF12937.5 001138375.2_53724001_1 - 5.4e-08 32.5 0.6 1.6e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.31 001138375.2_53724001_1 - 0.00066 19.4 0.2 0.0018 18.0 0.2 1.8 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.4 001138375.2_53724001_1 - 0.0018 18.5 0.7 33 5.0 0.0 4.7 4 1 0 4 4 4 1 PQQ-like domain Sod_Fe_N PF00081.20 001301559.1_53723001_1 - 4.4e-15 55.8 1.6 7.5e-15 55.0 1.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain OSCP PF00213.16 001320850.1_53723001_2 - 2.1e-43 148.3 2.1 2.8e-43 147.9 2.1 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Polyketide_cyc PF03364.18 001138447.2_53724001_3 - 8e-16 58.3 0.0 1.4e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.7 001138447.2_53724001_3 - 8e-06 26.0 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.11 001138447.2_53724001_3 - 0.0012 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) LAT PF15234.4 001138447.2_53724001_3 - 1.9 8.1 3.5 1.1 8.9 0.1 1.9 2 0 0 2 2 2 0 Linker for activation of T-cells NAM PF02365.13 001158829.2_53724001_1 - 2.8e-16 60.0 0.1 5.9e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 No apical meristem (NAM) protein DZR PF12773.5 001158829.2_53724001_1 - 0.048 13.6 2.9 0.28 11.1 2.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.4 001158829.2_53724001_1 - 0.053 12.8 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain YhfH PF14149.4 001158829.2_53724001_1 - 0.11 12.4 0.4 0.26 11.1 0.4 1.6 1 0 0 1 1 1 0 YhfH-like protein DUF3824 PF12868.5 001158829.2_53724001_1 - 0.64 10.5 6.6 0.06 13.9 1.0 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) SNARE PF05739.17 001138472.1_53723001_1 - 2e-10 40.4 2.1 3.3e-10 39.7 2.1 1.4 1 0 0 1 1 1 1 SNARE domain Pox_EPC_I2-L1 PF12575.6 001138472.1_53723001_1 - 0.074 13.1 2.1 1.1 9.4 0.2 2.4 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 SlyX PF04102.10 001138472.1_53723001_1 - 3.4 8.2 7.2 1.1 9.7 2.8 2.3 3 0 0 3 3 3 0 SlyX PurA PF04845.11 131232.1_53724120_1 - 3.8e-16 58.9 0.4 2.2e-05 23.8 0.2 1.9 1 1 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.6 131232.1_53724120_1 - 0.0035 17.3 1.9 0.29 11.1 0.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3276) PEPCK_ATP PF01293.18 131232.1_53724120_2 - 7e-25 87.5 0.0 9.5e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PurA PF04845.11 131232.1_53724120_3 - 2.2e-12 46.7 0.0 2.6e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 PurA ssDNA and RNA-binding protein RRN3 PF05327.9 145321.1_53724120_2 - 0.031 12.7 0.2 0.043 12.2 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tfb4 PF03850.12 137199.1_53723120_2 - 4.3e-10 39.3 1.7 4.3e-10 39.3 1.7 1.4 2 0 0 2 2 2 1 Transcription factor Tfb4 GPCR_chapero_1 PF11904.6 137199.1_53723120_3 - 6e-21 75.1 0.0 8.1e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 GPCR-chaperone Myb_CC_LHEQLE PF14379.4 145457.1_53723120_1 - 0.22 11.1 3.8 0.54 9.9 3.8 1.6 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2_assoc PF16606.3 145457.1_53723120_2 - 0.18 11.9 2.9 0.3 11.2 2.9 1.2 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers zf-RVT PF13966.4 145986.1_53723120_1 - 0.0013 19.4 1.2 0.0079 16.9 0.0 2.5 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase zf-RVT PF13966.4 145986.1_53723120_2 - 0.002 18.8 0.7 0.0056 17.4 0.7 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Nckap1 PF09735.7 145575.1_53722120_1 - 1.8e-32 112.3 0.0 2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein AMP-binding PF00501.26 145707.1_53725120_1 - 0.0018 16.8 0.7 0.0028 16.2 0.7 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PDCD7 PF16021.3 145707.1_53725120_2 - 0.024 13.6 15.5 0.038 13.0 15.5 1.2 1 0 0 1 1 1 0 Programmed cell death protein 7 DA1-like PF12315.6 145707.1_53725120_3 - 1.3e-27 96.5 0.3 1.7e-27 96.0 0.3 1.1 1 0 0 1 1 1 1 Protein DA1 CTP_synth_N PF06418.12 145707.1_53725120_3 - 4.1e-09 36.0 0.2 6e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus Metallophos PF00149.26 145707.1_53725120_3 - 5.8e-07 30.1 0.0 8.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 4HBT PF03061.20 001158907.2_53722001_2 - 3e-14 53.0 0.3 4.7e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.4 001158907.2_53722001_2 - 4.1e-06 27.1 0.5 6.5e-06 26.5 0.3 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.4 001158907.2_53722001_2 - 5.8e-05 23.1 0.2 8e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Pro_CA PF00484.17 001111889.1_53725001_1 - 5.8e-118 390.4 0.0 2.4e-40 138.2 0.0 3.1 3 0 0 3 3 3 3 Carbonic anhydrase CCG PF02754.14 001111889.1_53725001_1 - 0.0014 18.6 1.1 16 5.7 0.0 3.4 3 0 0 3 3 3 2 Cysteine-rich domain DUF3698 PF12479.6 001111889.1_53725001_1 - 0.0026 18.1 0.0 30 5.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3698) CX PF01705.17 001111889.1_53725001_1 - 0.0068 16.8 0.1 25 5.4 0.0 3.6 3 0 0 3 3 3 1 CX module DUF987 PF06174.9 001111889.1_53725001_1 - 0.12 12.2 0.0 37 4.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF987) Flp_Fap PF04964.12 001111889.1_53725001_1 - 1.3 8.8 6.9 41 4.0 0.2 3.4 3 0 0 3 3 3 0 Flp/Fap pilin component DUF1894 PF08979.9 001111889.1_53725001_3 - 0.06 13.6 0.0 1.1e+02 3.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1894) RAP1 PF07218.9 001308635.1_53721001_3 - 0.023 12.8 1.2 0.026 12.7 1.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HSF_DNA-bind PF00447.15 001138550.1_53724001_1 - 1.4e-28 99.2 0.2 3e-28 98.1 0.2 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Spc7 PF08317.9 001138550.1_53724001_1 - 0.1 11.3 3.1 0.15 10.7 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Pollen_allerg_1 PF01357.19 001301560.1_53723001_1 - 4.2e-27 93.9 0.0 6.6e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.16 001301560.1_53723001_1 - 5.8e-17 61.6 0.2 1.7e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase RskA PF10099.7 001301560.1_53723001_1 - 0.99 9.6 6.3 8.6 6.5 2.6 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA POX PF07526.9 001154708.1_53726001_3 - 2.4e-43 147.8 0.3 5.2e-43 146.8 0.3 1.6 1 0 0 1 1 1 1 Associated with HOX Homeobox_KN PF05920.9 001154708.1_53726001_3 - 6.7e-18 64.2 0.1 1.3e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.27 001154708.1_53726001_3 - 1.2e-06 28.1 0.1 2.7e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain AP2 PF00847.18 001112598.2_53724001_1 - 1.4e-23 82.7 8.1 3.7e-12 46.2 3.5 2.5 2 0 0 2 2 2 2 AP2 domain MFS_2 PF13347.4 001308124.1_53725001_3 - 1.6e-08 33.4 3.1 1.6e-08 33.4 3.1 3.0 2 2 0 2 2 2 1 MFS/sugar transport protein Eclosion PF04736.10 001308124.1_53725001_3 - 0.22 11.1 3.5 4.5 6.9 0.3 2.4 2 0 0 2 2 2 0 Eclosion hormone GRAM PF02893.18 001301448.1_53723001_1 - 1.1e-19 70.2 0.0 1.6e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Acyltransferase PF01553.19 001138627.1_53723001_1 - 3e-26 91.5 0.0 4.4e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ureide_permease PF07168.9 001138627.1_53723001_1 - 0.067 11.8 0.3 0.1 11.2 0.3 1.2 1 0 0 1 1 1 0 Ureide permease Mis12 PF05859.10 001301513.1_53722001_2 - 3.3e-20 72.4 0.0 8.7e-20 71.0 0.0 1.7 2 0 0 2 2 2 1 Mis12 protein Cep57_CLD_2 PF14197.4 001301513.1_53722001_2 - 0.26 11.3 3.2 1.5 8.8 3.1 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 GATA PF00320.25 001346966.1_53724001_2 - 1.9e-15 56.0 3.4 3.4e-15 55.2 3.4 1.4 1 0 0 1 1 1 1 GATA zinc finger Ribosomal_S7 PF00177.19 001138666.1_53724001_2 - 1.6e-09 37.5 0.1 2.4e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.19 001138666.1_53724001_3 - 6.5e-19 67.9 0.2 9.6e-19 67.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Endothelin PF00322.15 001138666.1_53724001_3 - 3.2 7.3 7.1 4 7.0 0.2 2.6 2 0 0 2 2 2 0 Endothelin family H_PPase PF03030.14 001138703.1_53723001_1 - 9.3e-22 77.3 6.0 5.7e-21 74.7 6.0 1.8 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase H_PPase PF03030.14 001138703.1_53723001_2 - 7.9e-16 57.7 0.0 1.1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Alba PF01918.19 001301562.1_53722001_3 - 3.7e-11 42.5 0.3 6.1e-11 41.9 0.3 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.6 001301562.1_53722001_3 - 0.00074 19.4 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P OsmC PF02566.17 001301562.1_53722001_3 - 0.023 15.0 0.1 0.042 14.2 0.1 1.3 1 0 0 1 1 1 0 OsmC-like protein Lipase_GDSL PF00657.20 001320496.1_53723001_3 - 7.1e-13 48.8 0.0 9.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.4 001320496.1_53723001_3 - 0.0052 17.1 0.1 0.058 13.7 0.1 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AUX_IAA PF02309.14 001165576.2_53723001_3 - 3.1e-76 256.3 0.0 4.3e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 AUX/IAA family DUF239 PF03080.13 001321717.1_53725001_1 - 5.8e-88 293.9 0.4 8e-88 293.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF239) DUF4409 PF14365.4 001321717.1_53725001_1 - 8.2e-37 126.2 0.0 1.5e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4409) DUF4106 PF13388.4 001321717.1_53725001_2 - 9 5.3 5.9 14 4.6 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) BRX PF08381.9 001165672.1_53724001_3 - 1.2e-26 91.7 0.7 2.3e-26 90.8 0.7 1.5 1 0 0 1 1 1 1 Transcription factor regulating root and shoot growth via Pin3 RCC1 PF00415.16 001165672.1_53724001_3 - 6.2e-16 58.6 0.0 1.7e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat BRX_N PF13713.4 001165672.1_53724001_3 - 9.9e-15 53.9 0.4 9.9e-15 53.9 0.4 2.1 2 0 0 2 2 1 1 Transcription factor BRX N-terminal domain FYVE PF01363.19 001165672.1_53724001_3 - 2.2e-14 53.2 9.6 6e-14 51.8 9.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger Rootletin PF15035.4 001165672.1_53724001_3 - 0.0011 19.0 7.5 0.003 17.5 7.5 1.7 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion WEMBL PF05701.9 001165672.1_53724001_3 - 0.0021 16.7 7.2 0.0031 16.1 7.2 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light FYVE_2 PF02318.14 001165672.1_53724001_3 - 0.0027 17.8 6.0 0.0027 17.8 6.0 2.6 3 0 0 3 3 2 1 FYVE-type zinc finger IncA PF04156.12 001165672.1_53724001_3 - 0.0037 16.9 3.3 0.0059 16.3 3.3 1.3 1 0 0 1 1 1 1 IncA protein APG6 PF04111.10 001165672.1_53724001_3 - 0.006 15.9 6.6 0.0097 15.2 6.6 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 TPR_MLP1_2 PF07926.10 001165672.1_53724001_3 - 0.0062 16.5 15.7 0.012 15.6 15.7 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4200 PF13863.4 001165672.1_53724001_3 - 0.01 16.1 12.6 0.022 15.0 12.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4164 PF13747.4 001165672.1_53724001_3 - 0.017 15.2 7.9 0.036 14.2 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) GIT_CC PF16559.3 001165672.1_53724001_3 - 0.022 14.7 3.6 0.08 12.9 3.6 2.0 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HMMR_C PF15908.3 001165672.1_53724001_3 - 0.028 14.6 4.1 0.057 13.5 4.1 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Snapin_Pallidin PF14712.4 001165672.1_53724001_3 - 0.034 14.4 10.0 0.083 13.2 10.0 1.6 1 0 0 1 1 1 0 Snapin/Pallidin HAUS-augmin3 PF14932.4 001165672.1_53724001_3 - 0.036 13.5 9.5 0.039 13.3 8.1 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.9 001165672.1_53724001_3 - 0.074 11.8 7.9 0.12 11.1 7.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein RCC1_2 PF13540.4 001165672.1_53724001_3 - 0.084 12.6 2.9 5.3 6.8 0.5 2.7 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat HALZ PF02183.16 001165672.1_53724001_3 - 0.088 12.9 7.8 0.051 13.7 4.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper AAA_23 PF13476.4 001165672.1_53724001_3 - 0.16 12.3 1.6 0.28 11.5 1.6 1.4 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.11 001165672.1_53724001_3 - 0.17 10.9 7.6 0.3 10.2 7.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.12 001165672.1_53724001_3 - 0.18 11.7 12.3 0.36 10.7 12.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.7 001165672.1_53724001_3 - 0.23 12.0 4.9 0.6 10.7 4.9 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF342 PF03961.11 001165672.1_53724001_3 - 0.28 9.6 3.7 0.43 9.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GrpE PF01025.17 001165672.1_53724001_3 - 0.3 10.6 7.7 0.59 9.6 7.7 1.4 1 0 0 1 1 1 0 GrpE YlqD PF11068.6 001165672.1_53724001_3 - 1.3 9.2 7.8 3 8.1 7.8 1.5 1 0 0 1 1 1 0 YlqD protein KELK PF15796.3 001165672.1_53724001_3 - 1.5 9.2 12.7 3.7 8.0 12.7 1.7 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mnd1 PF03962.13 001165672.1_53724001_3 - 2.1 8.1 11.2 0.12 12.1 6.0 1.5 2 0 0 2 2 1 0 Mnd1 family LMBR1 PF04791.14 001165672.1_53724001_3 - 2.1 7.0 5.7 3.2 6.4 5.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ZapB PF06005.10 001165672.1_53724001_3 - 2.2 8.7 15.2 0.82 10.0 11.3 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Golgin_A5 PF09787.7 001165672.1_53724001_3 - 3 7.1 12.0 0.23 10.8 7.1 1.5 2 0 0 2 2 1 0 Golgin subfamily A member 5 DUF16 PF01519.14 001165672.1_53724001_3 - 3.2 8.2 7.5 1.6 9.1 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.20 001165672.1_53724001_3 - 4.1 7.6 13.4 1.7 8.8 10.1 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.13 001165672.1_53724001_3 - 5.3 6.8 11.4 4.6 6.9 9.4 1.9 1 1 0 1 1 1 0 Septum formation initiator ADIP PF11559.6 001165672.1_53724001_3 - 5.8 6.9 14.2 15 5.6 14.2 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.4 001165672.1_53724001_3 - 9.2 5.4 13.8 7.3 5.7 11.7 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.4 001165672.1_53724001_3 - 9.3 6.5 8.3 3.2 8.0 4.7 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Hexapep PF00132.22 001323021.1_53723001_1 - 3.7e-10 39.0 0.0 0.0014 18.2 0.0 3.1 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.4 001323021.1_53723001_1 - 0.0053 16.4 0.0 0.03 13.9 0.0 2.3 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.10 001323021.1_53723001_1 - 0.07 12.0 0.0 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 L-fucokinase PsbP PF01789.14 001323898.1_53723001_2 - 3.6e-39 134.2 0.2 6.9e-39 133.3 0.1 1.5 2 0 0 2 2 2 1 PsbP PsbQ PF05757.9 001323898.1_53723001_2 - 0.00078 19.1 0.6 0.0012 18.5 0.6 1.3 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) API5 PF05918.9 001138921.1_53724001_1 - 1.1e-10 40.9 1.9 1.4e-10 40.5 1.9 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) API5 PF05918.9 001138921.1_53724001_2 - 4.7e-172 573.3 3.1 6.1e-172 572.9 3.1 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) AAA_13 PF13166.4 001138921.1_53724001_2 - 0.016 13.8 0.2 0.035 12.7 0.1 1.5 2 0 0 2 2 2 0 AAA domain DUF896 PF05979.10 001138921.1_53724001_2 - 0.038 13.7 0.1 0.13 12.0 0.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) DUF1539 PF07560.9 001138921.1_53724001_2 - 0.13 12.2 0.6 1.6 8.7 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) WCOR413 PF05562.9 001155133.1_53723001_2 - 2.5e-84 281.6 2.4 3.3e-84 281.2 2.4 1.1 1 0 0 1 1 1 1 Cold acclimation protein WCOR413 NpwBP PF12622.5 001150038.2_53722001_2 - 0.12 13.2 1.9 0.28 12.0 0.2 2.5 2 0 0 2 2 2 0 mRNA biogenesis factor G6PD_C PF02781.14 001165734.1_53723001_2 - 1.8e-90 302.9 0.0 2.3e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.20 001165734.1_53723001_2 - 4.5e-23 82.7 0.0 7e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain U-box PF04564.13 001150057.1_53723001_3 - 0.017 15.1 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 U-box domain Skp1 PF01466.17 001155161.2_53722001_1 - 2.1e-29 101.3 0.6 3.4e-29 100.6 0.6 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.13 001155161.2_53722001_1 - 2.2e-17 62.8 0.4 4.6e-17 61.8 0.4 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain AIRC PF00731.18 001139023.1_53724001_1 - 0.00057 19.3 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 AIR carboxylase Remorin_C PF03763.11 001139046.1_53724001_2 - 5.5e-33 113.0 21.0 5.5e-33 113.0 21.0 1.8 2 0 0 2 2 2 1 Remorin, C-terminal region T2SS-T3SS_pil_N PF13629.4 001139046.1_53724001_2 - 0.027 14.1 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Pilus formation protein N terminal region PTS_IIA PF02255.14 001139046.1_53724001_2 - 0.48 10.4 5.4 1.2 9.1 5.4 1.7 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit YlqD PF11068.6 001139046.1_53724001_2 - 5.7 7.2 8.1 5.1 7.4 6.8 1.6 1 1 0 1 1 1 0 YlqD protein Jacalin PF01419.15 001155267.1_53722001_1 - 2.3e-30 105.2 0.0 4.1e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Transposase_24 PF03004.12 001150234.1_53724001_3 - 2e-10 40.8 1.5 2e-10 40.8 1.5 3.2 2 1 1 3 3 3 1 Plant transposase (Ptta/En/Spm family) DUF3450 PF11932.6 001150234.1_53724001_3 - 0.0022 17.2 3.8 0.004 16.4 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ATG16 PF08614.9 001150234.1_53724001_3 - 0.0046 17.0 5.5 0.0046 17.0 5.5 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.7 001150234.1_53724001_3 - 0.011 15.6 9.5 0.037 13.9 9.5 1.9 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.16 001150234.1_53724001_3 - 0.014 15.5 0.4 0.062 13.5 0.4 2.1 1 0 0 1 1 1 0 TSC-22/dip/bun family Bap31 PF05529.10 001150234.1_53724001_3 - 0.017 14.6 2.9 0.032 13.7 2.9 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.13 001150234.1_53724001_3 - 0.062 12.9 3.1 0.18 11.5 3.1 1.7 1 0 0 1 1 1 0 Septum formation initiator TPR_MLP1_2 PF07926.10 001150234.1_53724001_3 - 0.12 12.4 10.1 0.3 11.0 10.1 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.9 001150234.1_53724001_3 - 0.13 11.0 7.7 0.26 10.0 7.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.10 001150234.1_53724001_3 - 0.18 11.7 11.2 0.029 14.3 6.5 2.0 2 0 0 2 2 2 0 Laminin Domain II ZapB PF06005.10 001150234.1_53724001_3 - 0.19 12.0 8.5 0.74 10.2 8.5 2.0 1 0 0 1 1 1 0 Cell division protein ZapB DUF4337 PF14235.4 001150234.1_53724001_3 - 0.25 11.3 2.7 0.67 9.9 2.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) APG6 PF04111.10 001150234.1_53724001_3 - 0.28 10.4 8.9 0.23 10.7 5.3 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.10 001150234.1_53724001_3 - 0.32 10.9 3.7 1.1 9.1 3.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ead_Ea22 PF13935.4 001150234.1_53724001_3 - 0.57 10.7 4.5 0.37 11.3 1.5 2.1 2 0 0 2 2 2 0 Ead/Ea22-like protein DUF4407 PF14362.4 001150234.1_53724001_3 - 0.74 9.0 3.2 1.4 8.1 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-Q PF13094.4 001150234.1_53724001_3 - 0.81 9.7 10.9 0.23 11.5 6.5 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TSNAXIP1_N PF15739.3 001150234.1_53724001_3 - 6.9 7.0 10.6 43 4.4 4.5 3.4 4 0 0 4 4 3 0 Translin-associated factor X-interacting N-terminus Macoilin PF09726.7 001150234.1_53724001_3 - 7.3 4.9 19.7 0.035 12.5 10.4 1.7 2 0 0 2 2 2 0 Transmembrane protein IncA PF04156.12 001150234.1_53724001_3 - 9.1 5.9 10.7 0.8 9.3 4.9 2.0 2 0 0 2 2 2 0 IncA protein zf-met2 PF12907.5 001150239.2_53723001_3 - 0.035 14.1 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding zf-RING_UBOX PF13445.4 001150246.2_53724001_3 - 0.0047 16.8 1.1 0.015 15.2 1.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001150246.2_53724001_3 - 0.0061 16.4 1.7 0.013 15.3 1.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.5 001150246.2_53724001_3 - 0.0081 16.3 1.5 0.018 15.2 1.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.3 001150246.2_53724001_3 - 0.017 14.7 3.0 0.017 14.7 3.0 2.8 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4 PF00097.23 001150246.2_53724001_3 - 0.017 14.8 1.3 0.039 13.7 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001150246.2_53724001_3 - 0.051 13.7 3.7 0.053 13.7 1.9 2.1 2 0 0 2 2 2 0 Ring finger domain Zn_ribbon_17 PF17120.3 001150246.2_53724001_3 - 0.47 10.0 4.0 0.32 10.5 1.1 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.4 001150246.2_53724001_3 - 1.8 8.3 5.8 0.16 11.7 0.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IQ PF00612.25 001174281.1_53724001_3 - 6.5e-11 40.9 8.6 2.6e-05 23.5 3.2 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF4005 PF13178.4 001174281.1_53724001_3 - 3.3e-05 24.3 14.2 3.3e-05 24.3 14.2 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF4005) R3H PF01424.20 001155333.2_53724001_1 - 5.5e-11 42.2 0.1 1.1e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 R3H domain SUZ PF12752.5 001155333.2_53724001_1 - 1e-10 42.1 1.6 2.3e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 SUZ domain PDH PF02153.15 001150271.1_53724001_3 - 5.9e-16 58.1 0.0 7.9e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.15 001150271.1_53724001_3 - 2.3e-06 28.0 0.0 4.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.17 001150271.1_53724001_3 - 7.8e-06 25.2 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.13 001150271.1_53724001_3 - 0.00029 20.9 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.14 001150271.1_53724001_3 - 0.0042 16.6 0.1 0.0098 15.4 0.1 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.20 001150271.1_53724001_3 - 0.017 15.8 0.0 0.034 14.9 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Rossmann-like PF10727.7 001150271.1_53724001_3 - 0.029 14.1 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain Ribosomal_S3_C PF00189.18 001139165.1_53723001_2 - 1.1e-24 86.5 0.2 3.7e-24 84.9 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.15 001139165.1_53723001_2 - 9.9e-12 44.4 0.2 1.6e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 KH domain ESR1_C PF12743.5 001150300.2_53722001_2 - 0.15 11.7 2.2 0.35 10.5 2.2 1.7 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Caskin-Pro-rich PF16907.3 001150300.2_53722001_2 - 4.7 7.7 14.5 53 4.3 0.0 3.0 2 1 1 3 3 3 0 Proline rich region of Caskin proteins Sec15 PF04091.10 001139200.2_53726001_2 - 6.3e-64 216.2 0.0 9.6e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Haemolytic PF01809.16 001150385.2_53722001_2 - 8.5e-26 89.5 0.9 8.5e-26 89.5 0.9 1.9 2 0 0 2 2 2 1 Haemolytic domain Sas10_Utp3 PF04000.13 001150510.1_53724001_3 - 3.4e-15 56.3 0.0 6.4e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family SesA PF17107.3 001150510.1_53724001_3 - 0.082 13.0 0.8 7.2 6.7 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CCB2_CCB4 PF11152.6 001139362.1_53723001_1 - 0.0019 17.4 0.1 0.0027 17.0 0.1 1.2 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 CCB2_CCB4 PF11152.6 001139362.1_53723001_3 - 6.9e-47 159.2 0.0 9.1e-47 158.8 0.0 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 GWT1 PF06423.10 001321565.1_53724001_2 - 3.4e-29 101.7 10.2 3.4e-29 101.7 10.2 3.0 3 1 0 3 3 3 1 GWT1 AP2 PF00847.18 145990.1_53724120_1 - 3.2e-13 49.6 1.7 3.2e-13 49.6 1.7 1.9 2 0 0 2 2 2 1 AP2 domain Cyclin_C PF02984.17 144503.1_53723120_1 - 3e-05 24.0 0.0 4.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.21 144503.1_53723120_2 - 2.7e-35 120.8 0.4 3.7e-35 120.4 0.4 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Metallophos PF00149.26 145672.1_53723120_1 - 0.013 15.9 0.1 0.016 15.6 0.1 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos_C PF14008.4 145672.1_53723120_2 - 0.00031 21.4 0.0 0.006 17.3 0.0 2.3 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_C PF14008.4 145672.1_53723120_3 - 0.026 15.2 0.0 0.044 14.5 0.0 1.3 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C DUF1644 PF07800.10 145984.1_53723120_3 - 1.8e-38 132.1 14.1 1.8e-19 70.3 1.5 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1644) zf-RING_2 PF13639.4 145984.1_53723120_3 - 1.8 8.7 10.1 27 5.0 10.1 2.5 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.4 145984.1_53723120_3 - 2.7 8.1 10.8 1.9e+03 -1.0 10.8 2.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.4 145984.1_53723120_3 - 4.1 7.2 14.0 4.1e+02 0.8 14.0 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COBRA PF04833.13 001112502.2_53725001_1 - 5e-54 182.5 0.0 1.1e-52 178.2 0.0 2.7 3 0 0 3 3 3 1 COBRA-like protein CBM_2 PF00553.17 001112502.2_53725001_1 - 2.9e-06 27.4 0.6 0.31 11.3 0.0 3.6 3 0 0 3 3 3 3 Cellulose binding domain Cyclotide PF03784.11 001112342.2_53722001_1 - 0.00042 20.2 8.2 0.0014 18.5 8.2 2.0 1 0 0 1 1 1 1 Cyclotide family SWIM PF04434.15 146483.1_53723120_3 - 3.6e-05 23.2 0.9 7.5e-05 22.2 0.9 1.5 1 0 0 1 1 1 1 SWIM zinc finger AT_hook PF02178.17 146483.1_53723120_3 - 2.7 8.0 7.7 8.2 6.6 7.7 1.9 1 0 0 1 1 1 0 AT hook motif PPR_2 PF13041.4 146516.1_53728120_1 - 1.7e-110 360.9 33.5 8e-16 57.9 0.1 14.0 4 4 12 16 16 16 15 PPR repeat family PPR_1 PF12854.5 146516.1_53728120_1 - 1.4e-97 318.9 23.5 8e-09 34.9 0.0 17.2 18 0 0 18 18 18 14 PPR repeat PPR PF01535.18 146516.1_53728120_1 - 1.7e-88 284.8 36.3 2.3e-06 27.3 0.1 18.3 18 0 0 18 18 18 18 PPR repeat PPR_3 PF13812.4 146516.1_53728120_1 - 1.8e-56 188.0 6.8 7.2e-09 35.5 0.0 9.7 7 3 3 11 11 11 9 Pentatricopeptide repeat domain PPR_long PF17177.2 146516.1_53728120_1 - 8.8e-21 74.1 0.0 1.8e-06 27.3 0.0 5.5 1 1 5 6 6 6 4 Pentacotripeptide-repeat region of PROPR RPM2 PF08579.9 146516.1_53728120_1 - 0.0047 17.1 1.1 0.25 11.5 0.0 3.7 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.7 146516.1_53728120_1 - 0.13 11.0 0.2 4.9 5.8 0.0 2.9 3 1 2 5 5 5 0 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.4 146515.1_53729120_2 - 8.3e-106 346.0 32.7 1.1e-15 57.4 0.1 13.8 4 4 11 15 15 15 15 PPR repeat family PPR_1 PF12854.5 146515.1_53729120_2 - 1.6e-95 312.3 23.8 1.1e-08 34.5 0.0 17.1 18 0 0 18 18 18 14 PPR repeat PPR PF01535.18 146515.1_53729120_2 - 2.4e-86 278.0 36.3 3e-06 27.0 0.1 18.4 18 0 0 18 18 18 18 PPR repeat PPR_3 PF13812.4 146515.1_53729120_2 - 3.1e-55 184.0 7.1 9.7e-09 35.1 0.0 9.5 7 3 3 11 11 11 9 Pentatricopeptide repeat domain PPR_long PF17177.2 146515.1_53729120_2 - 4.3e-20 71.9 0.0 2.5e-06 26.9 0.0 5.4 1 1 3 5 5 5 4 Pentacotripeptide-repeat region of PROPR RPM2 PF08579.9 146515.1_53729120_2 - 0.012 15.8 1.1 0.34 11.1 0.0 3.5 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.4 146517.1_53729120_1 - 4.4e-105 343.6 31.4 1.5e-15 57.0 0.1 13.8 5 4 11 16 16 16 15 PPR repeat family PPR_1 PF12854.5 146517.1_53729120_1 - 4.4e-93 304.5 23.9 1.5e-08 34.1 0.0 17.0 18 0 0 18 18 18 14 PPR repeat PPR PF01535.18 146517.1_53729120_1 - 9.8e-84 269.8 36.3 4.3e-06 26.5 0.1 18.5 18 0 0 18 18 18 17 PPR repeat PPR_3 PF13812.4 146517.1_53729120_1 - 2.5e-54 181.1 5.7 1.4e-08 34.6 0.0 9.4 7 2 2 10 10 10 9 Pentatricopeptide repeat domain PPR_long PF17177.2 146517.1_53729120_1 - 2.6e-19 69.3 0.0 3.8e-06 26.3 0.0 5.3 2 2 3 5 5 5 4 Pentacotripeptide-repeat region of PROPR RPM2 PF08579.9 146517.1_53729120_1 - 0.04 14.1 1.3 0.48 10.7 0.0 3.2 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) MFS_5 PF05631.12 146517.1_53729120_1 - 0.042 12.6 0.1 0.072 11.9 0.1 1.3 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM LRR_8 PF13855.4 146517.1_53729120_2 - 1.1e-09 37.8 6.9 2.9e-06 26.8 1.2 3.0 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.5 146517.1_53729120_2 - 8.6e-06 25.8 10.8 0.0021 18.3 0.8 4.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) DUF947 PF06102.10 146517.1_53729120_3 - 1.3e-22 80.4 13.4 1.9e-22 79.9 13.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF947) DUF1084 PF06454.9 001155924.2_53724001_1 - 1.3e-137 457.5 11.6 1.7e-137 457.1 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) FAE1_CUT1_RppA PF08392.10 001159045.2_53725001_3 - 8.6e-132 438.6 0.0 1.1e-131 438.3 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.8 001159045.2_53725001_3 - 2.4e-11 43.5 0.0 4.3e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.13 001159045.2_53725001_3 - 3.3e-07 30.3 0.0 5.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.17 001159045.2_53725001_3 - 0.00036 19.9 0.1 0.00054 19.3 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.8 001159045.2_53725001_3 - 0.0038 16.9 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Enolase_N PF03952.14 146532.1_53725120_1 - 1.3e-17 64.0 0.4 1.3e-17 64.0 0.4 1.7 2 0 0 2 2 2 1 Enolase, N-terminal domain U-box PF04564.13 146532.1_53725120_1 - 4.6e-06 26.6 0.2 1.8e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 U-box domain Med15 PF09606.8 146532.1_53725120_1 - 2.3 6.6 15.9 3.6 6.0 15.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TIMELESS PF04821.12 146532.1_53725120_1 - 8.9 5.4 9.3 1.7 7.7 4.5 1.9 2 0 0 2 2 2 0 Timeless protein Enolase_C PF00113.20 146532.1_53725120_2 - 3.3e-41 141.3 0.2 4.8e-40 137.5 0.1 2.0 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.14 146532.1_53725120_2 - 5.3e-09 36.2 0.2 1e-08 35.3 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain Arm PF00514.21 146532.1_53725120_2 - 0.051 13.5 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Enolase_C PF00113.20 146532.1_53725120_3 - 1.5e-31 109.7 0.1 1.9e-31 109.3 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.4 146532.1_53725120_3 - 0.059 12.9 0.1 0.091 12.3 0.1 1.2 1 0 0 1 1 1 0 Enolase C-terminal domain-like Oxidored_molyb PF00174.17 001288022.1_48627001_3 - 2e-58 196.7 0.0 3e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.14 001288022.1_48627001_3 - 8.8e-55 184.4 0.5 1.5e-54 183.6 0.5 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.19 001288022.1_48627001_3 - 1e-35 122.5 0.0 3.4e-35 120.8 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.22 001288022.1_48627001_3 - 1.9e-35 121.0 0.0 3.9e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.26 001288022.1_48627001_3 - 2.2e-22 78.9 0.0 4.2e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.10 001288022.1_48627001_3 - 0.0038 17.2 0.0 0.018 15.1 0.0 2.2 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Pkinase PF00069.23 001154688.2_53725001_3 - 8.3e-68 228.5 0.0 1.1e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001154688.2_53725001_3 - 1.9e-33 115.7 0.0 3.2e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001154688.2_53725001_3 - 3.1e-06 26.6 1.2 3.9e-06 26.2 0.2 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001154688.2_53725001_3 - 0.0001 21.6 0.0 0.00035 19.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.21 001154688.2_53725001_3 - 0.019 14.8 0.2 0.22 11.3 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_31 PF01055.24 001350284.1_53726001_2 - 1.8e-148 495.3 4.1 2.2e-148 495.0 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.4 001350284.1_53726001_2 - 1e-20 73.7 1.4 1e-19 70.5 0.1 3.0 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.2 001350284.1_53726001_2 - 1.9e-07 31.1 0.0 4.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NtCtMGAM_N PF16863.3 001350284.1_53726001_2 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Kelch_1 PF01344.23 001350330.1_53729001_3 - 1.8e-23 81.7 11.5 1.9e-14 52.8 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.4 001350330.1_53729001_3 - 1e-15 57.2 7.6 4.1e-07 29.9 0.0 5.5 4 1 2 6 6 6 3 Kelch motif Kelch_4 PF13418.4 001350330.1_53729001_3 - 4.4e-10 39.2 0.5 0.0036 17.1 0.1 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.13 001350330.1_53729001_3 - 5.7e-07 29.1 0.3 0.0027 17.5 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.4 001350330.1_53729001_3 - 0.00011 22.2 0.2 0.094 12.9 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Pkinase PF00069.23 001112270.1_53725001_2 - 2.3e-69 233.6 0.0 3.1e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001112270.1_53725001_2 - 7.1e-35 120.4 0.0 9.6e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001112270.1_53725001_2 - 3.8e-07 29.6 0.0 6.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001112270.1_53725001_2 - 8.4e-06 25.2 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001112270.1_53725001_2 - 0.00023 21.1 0.3 0.067 13.0 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family EF-hand_1 PF00036.30 001112270.1_53725001_2 - 0.0057 16.0 0.0 18 5.0 0.0 3.6 3 0 0 3 3 3 2 EF hand K-box PF01486.15 001111685.1_53723001_2 - 4.7e-29 100.3 9.2 4.7e-29 100.3 9.2 1.8 3 0 0 3 3 3 1 K-box region SRF-TF PF00319.16 001111685.1_53723001_2 - 3.9e-26 90.1 0.3 7.1e-26 89.3 0.3 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DASH_Dad3 PF08656.8 001111685.1_53723001_2 - 1.4 9.0 6.8 4.1 7.4 4.5 2.6 2 1 0 2 2 2 0 DASH complex subunit Dad3 ZapB PF06005.10 001111685.1_53723001_2 - 5.8 7.3 18.3 4.6 7.6 4.8 2.5 1 1 1 2 2 2 0 Cell division protein ZapB Band_7 PF01145.23 001111498.1_53723001_2 - 4.9e-22 78.7 0.6 7.1e-22 78.1 0.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.6 001111498.1_53723001_2 - 0.0091 15.0 2.1 0.012 14.5 2.1 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Med2 PF11214.6 001111498.1_53723001_2 - 0.049 13.7 0.1 0.085 12.9 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 Pkinase_Tyr PF07714.15 001111931.1_53726001_2 - 1.9e-47 161.6 0.0 2.5e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001111931.1_53726001_2 - 4.6e-42 144.1 0.0 6.6e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain B_lectin PF01453.22 001111931.1_53726001_2 - 9.4e-24 83.4 0.4 2.5e-23 82.0 0.4 1.8 1 0 0 1 1 1 1 D-mannose binding lectin S_locus_glycop PF00954.18 001111931.1_53726001_2 - 8.4e-22 77.7 2.5 2e-21 76.4 2.5 1.7 1 0 0 1 1 1 1 S-locus glycoprotein domain PAN_2 PF08276.9 001111931.1_53726001_2 - 9.5e-16 57.5 1.0 9.5e-16 57.5 1.0 2.3 2 0 0 2 2 2 1 PAN-like domain DUF3403 PF11883.6 001111931.1_53726001_2 - 9.4e-05 22.4 0.4 9.4e-05 22.4 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3403) APH PF01636.21 001111931.1_53726001_2 - 0.0028 17.5 0.1 0.0064 16.3 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EGF_MSP1_1 PF12946.5 001111931.1_53726001_2 - 0.012 15.6 3.1 0.027 14.4 3.1 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 EGF_3 PF12947.5 001111931.1_53726001_2 - 1.3 9.1 13.6 0.063 13.3 7.2 2.1 2 0 0 2 2 2 0 EGF domain PX PF00787.22 001112507.1_53727001_1 - 1 9.2 3.1 0.32 10.9 0.2 1.6 2 0 0 2 2 2 0 PX domain Lipoxygenase PF00305.17 001112507.1_53727001_3 - 2.2e-295 981.3 0.0 2.6e-295 981.1 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.21 001112507.1_53727001_3 - 1.6e-09 38.3 0.0 2.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Vac_ImportDeg PF09783.7 001136743.1_53723001_3 - 4.5e-49 166.2 0.0 6.6e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF4106 PF13388.4 001136748.1_53723001_1 - 3.5 6.6 7.7 5.2 6.1 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Ribosomal_L4 PF00573.20 001136748.1_53723001_2 - 3.7e-40 137.5 1.0 4e-40 137.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.4 001136748.1_53723001_2 - 4.9e-27 93.6 2.7 4.9e-27 93.6 2.7 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain WD40 PF00400.30 001136821.1_53725001_2 - 2.3e-11 43.9 3.9 0.23 12.3 0.3 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Me-amine-dh_H PF06433.9 001136821.1_53725001_2 - 0.038 12.7 0.0 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) DsbC_N PF10411.7 001136821.1_53725001_2 - 0.2 11.0 0.0 0.62 9.4 0.0 1.8 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Rhomboid PF01694.20 001137164.1_53724001_1 - 0.00035 20.4 1.6 0.00035 20.4 1.6 1.7 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.20 001137164.1_53724001_2 - 1.3e-21 77.0 12.3 3.3e-17 62.7 7.4 2.4 2 0 0 2 2 2 2 Rhomboid family OTU PF02338.17 001138051.1_53723001_3 - 1.2e-11 45.0 0.1 2e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease BBP1_C PF15272.4 001138051.1_53723001_3 - 0.013 15.2 0.4 0.022 14.4 0.4 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Peptidase_C65 PF10275.7 001138051.1_53723001_3 - 0.049 13.0 0.2 0.4 10.0 0.2 2.1 1 1 1 2 2 2 0 Peptidase C65 Otubain Palm_thioest PF02089.13 001138542.1_53723001_3 - 1.4e-33 116.1 0.0 1.9e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.12 001138542.1_53723001_3 - 0.007 15.8 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Glyco_transf_22 PF03901.15 001137697.1_53725001_3 - 4.4e-114 381.8 25.7 5.3e-114 381.6 25.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.4 001137697.1_53725001_3 - 0.83 9.8 22.6 6.6 6.8 17.2 3.4 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase RRM_1 PF00076.20 001138853.1_53724001_3 - 1e-23 82.8 0.0 7e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Response_reg PF00072.22 001143590.1_53723001_3 - 8.2e-22 77.4 0.0 1.2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain G-patch PF01585.21 001155282.1_53722001_1 - 6.3e-17 61.1 1.9 1.2e-16 60.2 1.9 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.5 001155282.1_53722001_1 - 1.4e-05 24.9 1.0 1.4e-05 24.9 1.0 1.8 2 0 0 2 2 2 1 G-patch domain TANGO2 PF05742.10 001155288.1_53723001_2 - 2.5e-69 234.0 0.0 3e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 AAT PF03417.14 001155288.1_53723001_2 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Y_phosphatase2 PF03162.11 001156049.1_53723001_2 - 7.4e-60 201.1 0.0 1e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.4 001156049.1_53723001_2 - 3e-07 30.5 0.0 4.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.25 001156049.1_53723001_2 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.18 001156049.1_53723001_2 - 0.092 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Mito_carr PF00153.25 001155552.1_53724001_2 - 1.3e-43 146.7 1.2 2.3e-15 56.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF296 PF03479.13 001153520.1_53724001_2 - 3.9e-29 101.0 0.9 7.3e-29 100.1 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF296) DUF3331 PF11811.6 001153520.1_53724001_2 - 0.037 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) BAF1_ABF1 PF04684.11 001153520.1_53724001_2 - 0.61 8.9 9.7 0.86 8.4 9.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor LEA_3 PF03242.11 001156331.1_53722001_3 - 3.7 8.2 7.2 2.7 8.6 4.4 2.3 1 1 1 2 2 2 0 Late embryogenesis abundant protein ADK PF00406.20 001146901.1_53723001_1 - 0.00022 21.2 0.0 0.0003 20.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK PF00406.20 001146901.1_53723001_3 - 1.4e-36 125.8 0.0 8.5e-35 119.9 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.4 001146901.1_53723001_3 - 1e-29 103.5 0.0 7.3e-26 91.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.4 001146901.1_53723001_3 - 6.3e-06 26.6 0.0 1.5e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001146901.1_53723001_3 - 0.0094 16.0 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.15 001146901.1_53723001_3 - 0.04 13.4 0.1 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_19 PF13245.4 001146901.1_53723001_3 - 0.21 11.8 0.2 0.36 11.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.19 001155094.1_53724001_2 - 1.3e-08 34.6 9.9 3.6e-08 33.2 3.6 2.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.13 001155094.1_53724001_2 - 6.5e-07 29.2 1.7 6.5e-07 29.2 1.7 2.7 2 0 0 2 2 2 1 Basic region leucine zipper GIT_CC PF16559.3 001155094.1_53724001_2 - 0.0051 16.7 0.9 0.0051 16.7 0.9 3.2 2 2 1 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor ATG16 PF08614.9 001155094.1_53724001_2 - 0.0054 16.8 7.3 0.0054 16.8 7.3 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Atg14 PF10186.7 001155094.1_53724001_2 - 0.49 9.3 7.2 0.75 8.7 7.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.10 001155094.1_53724001_2 - 1.7 9.0 15.4 0.029 14.7 6.4 2.3 2 0 0 2 2 2 0 Cell division protein ZapB IncA PF04156.12 001155094.1_53724001_2 - 6 6.5 15.5 0.12 12.0 3.7 2.1 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.11 001155094.1_53724001_2 - 8 7.0 9.8 0.33 11.5 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HLH PF00010.24 001147447.1_53723001_2 - 2.8e-12 46.3 0.5 5.8e-12 45.3 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ACT PF01842.23 001147447.1_53723001_2 - 0.00023 20.7 0.3 0.00048 19.7 0.3 1.5 1 0 0 1 1 1 1 ACT domain F-box-like PF12937.5 001152411.1_53725001_1 - 0.0034 17.1 0.2 0.0086 15.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like HMG_box PF00505.17 001157676.1_53722001_3 - 4.5e-22 78.1 1.4 6.3e-22 77.6 1.4 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001157676.1_53722001_3 - 1.1e-13 51.5 1.2 1.6e-13 50.9 1.2 1.3 1 0 0 1 1 1 1 HMG-box domain DUF1074 PF06382.9 001157676.1_53722001_3 - 0.004 17.2 0.1 0.0052 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1074) Pkinase PF00069.23 001152870.1_53726001_1 - 7.8e-26 90.9 0.0 1.4e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001152870.1_53726001_1 - 8.4e-06 25.1 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001152870.1_53726001_3 - 2.8e-33 115.3 2.1 4.2e-33 114.7 2.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001152870.1_53726001_3 - 3e-17 62.6 0.5 4.4e-17 62.1 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001152870.1_53726001_3 - 7.5e-05 22.0 0.9 0.00012 21.4 0.9 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GST_C_2 PF13410.4 001147226.1_53724001_3 - 6.1e-13 48.4 0.2 1.6e-12 47.0 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001147226.1_53724001_3 - 3.6e-12 46.3 0.0 6.6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001147226.1_53724001_3 - 1.8e-11 44.0 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001147226.1_53724001_3 - 4.9e-07 29.7 0.0 1.1e-06 28.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001147226.1_53724001_3 - 0.0074 15.9 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001147226.1_53724001_3 - 0.039 14.2 0.0 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-CCCH PF00642.22 001152893.1_53723001_1 - 2.6e-10 39.8 3.2 7.2e-10 38.4 3.2 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.4 001152893.1_53723001_1 - 3e-08 33.3 9.5 3e-08 33.3 9.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001152893.1_53723001_1 - 1.1e-05 25.1 14.5 2.3e-05 24.1 14.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.4 001152893.1_53723001_1 - 2.1e-05 24.1 13.3 4.5e-05 23.1 13.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001152893.1_53723001_1 - 2.1e-05 24.1 14.4 4.5e-05 23.1 14.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001152893.1_53723001_1 - 8.4e-05 22.6 12.2 0.00022 21.3 12.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.4 001152893.1_53723001_1 - 0.00059 19.7 13.1 0.0014 18.5 13.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.3 001152893.1_53723001_1 - 0.0034 17.3 6.3 0.0034 17.3 6.3 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.4 001152893.1_53723001_1 - 0.11 12.3 11.0 0.22 11.3 11.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.6 001152893.1_53723001_1 - 0.46 10.2 8.1 0.89 9.3 8.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.4 001152893.1_53723001_1 - 2.9 8.0 17.8 0.062 13.3 10.8 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.5 001152893.1_53723001_1 - 4.2 7.6 12.4 19 5.5 12.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain MtN3_slv PF03083.14 001150167.1_53723001_2 - 3.2e-45 151.9 17.5 2.6e-23 81.7 6.5 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.12 001150167.1_53723001_2 - 0.0063 16.1 3.7 0.66 9.7 0.6 2.7 2 0 0 2 2 2 2 PQ loop repeat COX7a PF02238.13 001150167.1_53723001_2 - 4.5 7.6 8.0 17 5.8 0.3 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII Aa_trans PF01490.16 001147482.1_53724001_1 - 8.8e-48 162.9 23.2 1.1e-47 162.5 23.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.11 001147482.1_53724001_1 - 7.4e-05 21.8 26.9 0.00043 19.3 26.9 1.9 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family START PF01852.17 001148931.1_53724001_2 - 3.1e-08 33.2 0.0 4.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 START domain Thaumatin PF00314.15 001147520.1_53724001_1 - 1.5e-81 273.2 8.0 2.1e-81 272.7 8.0 1.2 1 0 0 1 1 1 1 Thaumatin family YbjQ_1 PF01906.15 001155206.1_53722001_2 - 0.11 13.0 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative heavy-metal-binding Transferase PF02458.13 001148493.1_53724001_2 - 2e-74 250.7 0.0 2.5e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Transferase family UQ_con PF00179.24 001154716.1_53723001_1 - 6.9e-36 122.8 0.1 9.7e-36 122.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAD_binding_4 PF01565.21 001147309.1_53724001_2 - 1e-29 102.9 2.6 1.4e-29 102.4 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.10 001147309.1_53724001_2 - 6e-22 77.4 0.1 1.6e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like CDP-OH_P_transf PF01066.19 001154223.1_53723001_3 - 5.7e-12 46.1 0.7 5.7e-12 46.1 0.7 2.4 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIF PF03031.16 001154990.1_53723001_3 - 1.1e-36 125.9 0.0 1.4e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydrolase_3 PF07859.11 001148064.1_53723001_1 - 4.1e-48 163.9 0.6 6.2e-48 163.3 0.6 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.26 001148064.1_53723001_1 - 3.1e-06 26.3 0.0 5.4e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.18 001148064.1_53723001_1 - 0.0016 18.0 0.5 0.0086 15.6 0.5 1.9 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.9 001148064.1_53723001_1 - 0.0018 17.2 0.0 0.0026 16.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.5 001148064.1_53723001_1 - 0.034 12.9 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme ILVD_EDD PF00920.19 001177037.1_53725001_2 - 4e-214 711.9 0.0 4.6e-214 711.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family zf-RING_UBOX PF13445.4 001175920.1_53724001_2 - 0.0064 16.4 1.3 0.017 15.0 1.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.5 001175920.1_53724001_2 - 0.011 15.9 6.2 0.011 15.9 6.2 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.4 001175920.1_53724001_2 - 0.019 15.1 8.3 0.019 15.1 8.3 2.5 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.4 001175920.1_53724001_2 - 0.021 14.5 2.9 0.059 13.1 2.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.3 001175920.1_53724001_2 - 0.063 12.8 1.5 0.22 11.0 1.5 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.3 001175920.1_53724001_2 - 0.12 12.0 4.5 0.23 11.1 3.3 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.4 001175920.1_53724001_2 - 4.6 7.1 10.6 0.35 10.7 5.4 2.0 2 0 0 2 2 2 0 zinc-RING finger domain TPP_enzyme_N PF02776.16 001175718.1_53726001_2 - 9.1e-16 57.8 0.2 2e-15 56.7 0.2 1.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ABC_tran PF00005.25 001176463.1_53723001_3 - 2.3e-15 57.2 0.0 3.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.4 001176463.1_53723001_3 - 0.00018 21.3 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.4 001176463.1_53723001_3 - 0.0009 18.8 0.1 0.0024 17.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.4 001176463.1_53723001_3 - 0.0021 18.5 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.4 001176463.1_53723001_3 - 0.0042 17.3 0.0 0.0069 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.4 001176463.1_53723001_3 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.17 001176463.1_53723001_3 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.19 001176463.1_53723001_3 - 0.073 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.4 001176463.1_53723001_3 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.18 001176463.1_53723001_3 - 0.17 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Inos-1-P_synth PF01658.15 001174358.1_53722001_2 - 1.4e-29 102.4 0.0 2e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.10 001174358.1_53722001_2 - 9.4e-25 87.5 0.0 1.1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NR_Repeat PF14046.4 001174358.1_53722001_3 - 0.27 11.3 7.4 2.7 8.0 0.8 2.4 2 0 0 2 2 2 0 Nuclear receptor repeat Lectin_legB PF00139.17 001175750.1_53726001_3 - 7.4e-77 258.1 0.0 9.7e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 Legume lectin domain Pkinase PF00069.23 001175750.1_53726001_3 - 9e-48 162.8 0.0 1.2e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001175750.1_53726001_3 - 1.1e-42 146.0 0.0 3.6e-42 144.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001175750.1_53726001_3 - 0.0044 16.8 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family UPF0051 PF01458.15 001175347.1_53723001_2 - 3.7e-62 209.7 0.1 4.4e-62 209.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Lir1 PF07207.9 001175347.1_53723001_2 - 0.051 13.7 0.1 0.096 12.8 0.1 1.4 1 0 0 1 1 1 0 Light regulated protein Lir1 Acyl-CoA_dh_1 PF00441.22 001175117.1_53723001_1 - 6.8e-44 149.6 0.0 1.1e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.14 001175117.1_53723001_1 - 1.4e-35 122.2 0.1 3.1e-35 121.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.17 001175117.1_53723001_1 - 5.8e-25 87.2 0.1 9.7e-25 86.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.9 001175117.1_53723001_1 - 7.5e-14 52.0 0.0 1.7e-13 50.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.6 001175117.1_53723001_1 - 0.0066 16.0 0.1 0.028 13.9 0.1 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Amidase PF01425.19 001177199.1_53724001_2 - 2.7e-60 204.5 1.1 4.4e-59 200.5 1.1 2.0 1 1 0 1 1 1 1 Amidase zf-C3HC4_3 PF13920.4 001174248.1_53723001_3 - 2.6e-16 59.1 12.7 5e-16 58.2 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001174248.1_53723001_3 - 1.2e-07 31.3 10.9 2.2e-07 30.5 10.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.4 001174248.1_53723001_3 - 1.1e-06 28.7 14.0 2.4e-06 27.6 14.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.4 001174248.1_53723001_3 - 0.0027 17.5 12.3 0.0049 16.7 12.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.12 001174248.1_53723001_3 - 0.046 13.3 7.5 0.11 12.0 7.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_2 PF13923.4 001174248.1_53723001_3 - 0.047 13.4 13.7 0.088 12.5 13.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.4 001174248.1_53723001_3 - 0.86 9.2 10.8 1.6 8.4 10.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_hydro_9 PF00759.17 001323015.1_53725001_3 - 2.1e-139 465.4 8.1 2.8e-139 465.0 8.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Galactosyl_T PF01762.19 001346985.1_53725001_2 - 6.3e-49 166.3 0.5 4.5e-48 163.5 0.1 2.0 2 0 0 2 2 2 1 Galactosyltransferase DUF4094 PF13334.4 001346985.1_53725001_2 - 2.9e-28 98.0 0.0 7.5e-28 96.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) Fringe PF02434.14 001346985.1_53725001_2 - 0.0022 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Spectrin PF00435.19 001346985.1_53725001_2 - 0.2 12.0 1.2 0.35 11.3 1.2 1.3 1 0 0 1 1 1 0 Spectrin repeat Redoxin PF08534.8 001319561.1_29522001_1 - 1.5e-30 105.7 0.0 2e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.19 001319561.1_29522001_1 - 1.1e-13 51.1 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family NAD_binding_10 PF13460.4 001319561.1_29522001_1 - 0.02 14.7 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding KRAB PF01352.25 023382.1_26226120_2 - 1.7e-20 72.3 0.2 2.9e-20 71.5 0.2 1.4 1 0 0 1 1 1 1 KRAB box zf-H2C2_2 PF13465.4 023382.1_26226120_3 - 1.9e-06 27.9 31.8 0.0032 17.7 1.1 6.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-H2C2_5 PF13909.4 023382.1_26226120_3 - 0.093 12.4 3.2 0.27 10.9 3.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.24 023382.1_26226120_3 - 0.45 10.9 24.0 2 8.9 2.2 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Ldh_1_C PF02866.16 001320106.1_29623001_3 - 3e-45 154.0 0.0 7.8e-45 152.7 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.21 001320106.1_29623001_3 - 2.1e-39 134.7 0.2 3.7e-39 133.9 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain A2M_comp PF07678.12 001320161.1_39729001_1 - 1.9e-80 269.8 0.2 2.7e-80 269.3 0.2 1.2 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_recep PF07677.12 001320161.1_39729001_1 - 5e-29 100.8 0.0 1.8e-28 99.0 0.0 2.0 1 0 0 1 1 1 1 A-macroglobulin receptor A2M PF00207.20 001320161.1_39729001_1 - 2.4e-27 94.5 0.0 1.1e-25 89.1 0.0 2.7 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.12 001320161.1_39729001_1 - 7.5e-23 81.3 0.1 2e-20 73.4 0.0 3.2 3 0 0 3 3 3 1 Alpha-2-macroglobulin family N-terminal region NTR PF01759.19 001320161.1_39729001_1 - 8e-21 73.7 0.0 2e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 UNC-6/NTR/C345C module A2M_N PF01835.17 001320161.1_39729001_1 - 7.5e-19 67.9 0.1 1.9e-17 63.4 0.0 2.9 2 0 0 2 2 2 1 MG2 domain Thiol-ester_cl PF10569.7 001320161.1_39729001_1 - 1.8e-12 46.6 0.1 3.6e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region ANATO PF01821.16 001320161.1_39729001_1 - 6.2e-10 39.6 9.4 1.4e-09 38.5 9.4 1.7 1 0 0 1 1 1 1 Anaphylotoxin-like domain SQHop_cyclase_C PF13243.4 001320161.1_39729001_1 - 0.14 11.1 0.3 0.4 9.6 0.1 1.8 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.4 001320161.1_39729001_1 - 0.24 10.3 1.3 2.4 7.1 0.2 2.2 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.19 001320161.1_39729001_1 - 0.57 9.8 4.4 0.19 11.3 0.2 2.4 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat zf-CCHC PF00098.21 126534.1_26229120_1 - 5.6e-06 26.1 2.4 1.8e-05 24.5 2.4 2.0 1 0 0 1 1 1 1 Zinc knuckle Ig_2 PF13895.4 001302661.1_39522001_1 - 2.3e-05 24.5 0.6 0.19 12.0 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001302661.1_39522001_1 - 0.00025 21.0 0.0 0.0006 19.8 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.14 001302661.1_39522001_1 - 0.00027 20.8 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.4 001302661.1_39522001_1 - 0.0004 20.8 0.1 0.59 10.7 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001302661.1_39522001_1 - 0.0013 18.8 0.4 4.7 7.3 0.2 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Methyltransf_3 PF01596.15 001282138.1_39522001_1 - 2.9e-15 55.9 0.0 3.8e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001282138.1_39522001_1 - 1.6e-11 45.1 0.0 3.5e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.17 001282138.1_39522001_1 - 0.00082 19.1 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.4 001282138.1_39522001_1 - 0.023 14.3 0.0 0.038 13.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain TFIID-31kDa PF02291.13 001285801.1_39523001_1 - 3e-49 166.0 0.0 4.2e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001285801.1_39523001_1 - 1.5e-07 31.8 0.2 2.8e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001285801.1_39523001_1 - 3e-06 27.4 0.1 5.6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein AAA_17 PF13207.4 001285801.1_39523001_1 - 5e-05 23.6 0.1 0.0001 22.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.4 001285801.1_39523001_1 - 6.9e-05 23.0 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Bromo_TP PF07524.11 001285801.1_39523001_1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001285801.1_39523001_1 - 0.00026 21.3 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Histone PF00125.22 001285801.1_39523001_1 - 0.00038 20.7 0.3 0.00066 19.9 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 AAA_16 PF13191.4 001285801.1_39523001_1 - 0.003 17.8 0.1 0.0055 17.0 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain CENP-T_C PF15511.4 001285801.1_39523001_1 - 0.0042 17.0 0.1 0.0075 16.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold RuvB_N PF05496.10 001285801.1_39523001_1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.4 001285801.1_39523001_1 - 0.014 15.4 0.5 0.056 13.5 0.5 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.13 001285801.1_39523001_1 - 0.021 14.6 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.4 001285801.1_39523001_1 - 0.027 14.6 0.1 0.054 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.15 001285801.1_39523001_1 - 0.034 14.0 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.12 001285801.1_39523001_1 - 0.035 14.0 0.8 0.059 13.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SKI PF01202.20 001285801.1_39523001_1 - 0.035 14.1 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.4 001285801.1_39523001_1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain ADK PF00406.20 001285801.1_39523001_1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase AAA_32 PF13654.4 001285801.1_39523001_1 - 0.13 10.8 0.2 0.95 8.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF3355 PF11835.6 001302773.1_39523001_1 - 4.5 6.8 9.5 6.4 6.3 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) V-set PF07686.15 001302773.1_39523001_3 - 0.0089 16.0 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Chordopox_A13L PF05961.9 001302773.1_39523001_3 - 0.03 14.4 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF4834 PF16118.3 001302773.1_39523001_3 - 0.091 13.6 0.2 0.2 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Blt1 PF12754.5 001304801.1_39521001_1 - 0.019 15.2 0.1 0.022 15.0 0.1 1.1 1 0 0 1 1 1 0 Blt1 N-terminal domain Na_H_Exchanger PF00999.19 033801.1_26227120_1 - 1.3e-51 175.5 32.0 3.2e-47 161.0 20.9 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.19 033801.1_26227120_2 - 2.1e-05 23.3 0.0 3.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-tcix PF14952.4 001283524.1_29524001_1 - 1.9e-20 72.1 7.3 4.3e-20 70.9 7.3 1.7 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.7 001283524.1_29524001_1 - 0.0071 15.6 1.9 0.02 14.2 1.9 1.8 1 0 0 1 1 1 1 Mu-like prophage protein Com ADH_zinc_N PF00107.24 001285395.1_29523001_3 - 1.8e-27 95.6 0.1 3.2e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001285395.1_29523001_3 - 5.8e-25 87.2 0.9 1.5e-24 85.9 0.9 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.3 001285395.1_29523001_3 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.4 001285395.1_29523001_3 - 0.00027 21.8 0.0 0.00055 20.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.12 001285395.1_29523001_3 - 0.005 16.3 0.1 0.009 15.5 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 7tm_4 PF13853.4 001006595.1_45722001_1 - 4.7e-94 315.1 22.7 5.4e-94 314.9 22.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001006595.1_45722001_1 - 2.1e-16 59.8 21.5 7.3e-16 58.1 21.5 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001006595.1_45722001_1 - 1e-10 41.3 15.6 2.3e-10 40.2 15.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001006595.1_45722001_1 - 0.024 13.8 9.7 0.0055 15.9 6.4 1.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001000107.2_45722001_1 - 3.6e-45 154.7 18.6 4.5e-45 154.4 18.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000107.2_45722001_1 - 5e-30 104.5 17.7 8.7e-30 103.7 17.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BCAS3 PF12490.6 135471.1_26224120_3 - 0.007 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 HIT PF01230.21 001166197.1_39521001_1 - 1.4e-26 92.9 0.1 1.8e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.6 001166197.1_39521001_1 - 6.9e-07 29.6 0.0 9.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.13 001166197.1_39521001_1 - 0.072 12.8 0.0 0.094 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Cadherin PF00028.15 001082590.1_39729001_1 - 2e-70 233.1 0.0 4.7e-15 55.7 0.0 6.4 6 1 0 6 6 6 5 Cadherin domain Cadherin_tail PF15974.3 001082590.1_39729001_1 - 2.2e-63 212.4 4.7 3.6e-63 211.7 4.7 1.3 1 0 0 1 1 1 1 Cadherin C-terminal cytoplasmic tail, catenin-binding region Cadherin_2 PF08266.10 001082590.1_39729001_1 - 5.1e-31 106.2 0.5 5.6e-28 96.4 0.2 3.5 4 0 0 4 4 4 2 Cadherin-like Cadherin_C_2 PF16492.3 001082590.1_39729001_1 - 1.1e-06 29.1 0.3 2.7e-06 27.9 0.3 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Cadherin PF00028.15 001082564.1_39729001_3 - 1.1e-79 262.9 0.0 1.7e-18 66.7 0.0 6.3 5 1 1 6 6 6 6 Cadherin domain Cadherin_2 PF08266.10 001082564.1_39729001_3 - 6.9e-35 118.6 0.0 2.5e-32 110.4 0.0 4.3 5 0 0 5 5 5 1 Cadherin-like Cadherin_C_2 PF16492.3 001082564.1_39729001_3 - 5.3e-27 94.3 0.1 1.1e-26 93.3 0.1 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Cadherin_tail PF15974.3 001082564.1_39729001_3 - 2e-25 89.5 3.3 4e-25 88.5 3.3 1.4 1 0 0 1 1 1 1 Cadherin C-terminal cytoplasmic tail, catenin-binding region Cadherin_3 PF16184.3 001082564.1_39729001_3 - 0.00027 20.8 4.7 7.5 6.5 0.0 4.7 4 1 1 5 5 5 2 Cadherin-like Cadherin PF00028.15 001082560.1_39729001_3 - 1.2e-81 269.2 0.1 8.7e-17 61.2 0.0 6.2 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.10 001082560.1_39729001_3 - 1.8e-35 120.5 0.2 5.1e-32 109.4 0.0 4.6 6 0 0 6 6 6 1 Cadherin-like Cadherin_tail PF15974.3 001082560.1_39729001_3 - 2e-25 89.5 3.3 4e-25 88.6 3.3 1.5 1 0 0 1 1 1 1 Cadherin C-terminal cytoplasmic tail, catenin-binding region Cadherin_C_2 PF16492.3 001082560.1_39729001_3 - 8.1e-25 87.3 0.4 1.6e-24 86.3 0.4 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Cadherin PF00028.15 001082562.1_39729001_2 - 1.8e-78 258.9 0.0 1.8e-17 63.5 0.1 6.2 5 1 1 6 6 6 6 Cadherin domain Cadherin_2 PF08266.10 001082562.1_39729001_2 - 9.9e-33 111.7 0.0 1.4e-28 98.4 0.0 4.1 5 0 0 5 5 5 2 Cadherin-like Cadherin_tail PF15974.3 001082562.1_39729001_2 - 2.2e-25 89.4 3.3 4.7e-25 88.3 3.3 1.5 1 0 0 1 1 1 1 Cadherin C-terminal cytoplasmic tail, catenin-binding region Cadherin_C_2 PF16492.3 001082562.1_39729001_2 - 5.1e-23 81.5 0.1 1.1e-22 80.4 0.1 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Cadherin_3 PF16184.3 001082562.1_39729001_2 - 0.01 15.7 4.6 3.9 7.4 0.0 4.5 4 1 1 5 5 5 1 Cadherin-like DUF4958 PF16319.3 001082562.1_39729001_2 - 0.16 9.9 0.1 0.24 9.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4958) THUMP PF02926.15 135661.1_26226120_1 - 0.0071 16.3 2.6 0.025 14.5 0.0 2.7 3 0 0 3 3 3 1 THUMP domain UPF0020 PF01170.16 135661.1_26226120_2 - 2.2e-18 66.5 0.0 4.5e-18 65.5 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.4 135661.1_26226120_2 - 1.5e-09 38.3 0.0 2.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 135661.1_26226120_2 - 2.6e-09 36.9 0.0 4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 135661.1_26226120_2 - 5.9e-08 33.1 0.0 9.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.12 135661.1_26226120_2 - 5.5e-06 25.9 0.0 8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.16 135661.1_26226120_2 - 1e-05 24.9 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.10 135661.1_26226120_2 - 0.0016 19.0 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Kringle PF00051.16 135824.1_26224120_1 - 1.9e-49 165.7 27.2 1.6e-26 92.2 4.2 4.5 4 1 0 4 4 4 4 Kringle domain Trypsin PF00089.24 135824.1_26224120_2 - 2.3e-44 151.7 0.2 3.6e-44 151.1 0.2 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 135824.1_26224120_2 - 0.019 15.2 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) DUF4542 PF15075.4 001193729.1_29621001_1 - 1.5e-55 187.1 0.1 1.7e-55 186.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) EAR PF07897.9 001193729.1_29621001_1 - 0.084 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression DUF4559 PF15112.4 001193763.1_29625001_1 - 5.3e-104 348.1 0.6 7.1e-104 347.7 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) Histone PF00125.22 001193825.1_29623001_2 - 3.4e-25 88.8 0.4 6.4e-25 87.9 0.4 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001193825.1_29623001_2 - 1.3e-06 28.4 0.0 6.7e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.11 001193825.1_29623001_2 - 0.0071 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.3 001193825.1_29623001_2 - 0.018 14.9 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein WD40 PF00400.30 001193853.1_29624001_3 - 2.3e-06 28.1 1.7 0.02 15.6 1.6 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Pou PF00157.15 001194259.1_29623001_2 - 1.2e-38 130.8 0.3 2e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001194259.1_29623001_2 - 2.7e-18 65.4 1.5 8.1e-18 63.9 0.3 2.1 2 0 0 2 2 2 1 Homeobox domain HTH_31 PF13560.4 001194259.1_29623001_2 - 0.017 15.4 0.0 0.071 13.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Homeobox_KN PF05920.9 001194259.1_29623001_2 - 0.054 13.3 0.2 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Homeobox KN domain DUF4682 PF15733.3 001194353.1_29622001_1 - 2.3e-30 105.6 0.1 3.4e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4682) Rhomboid PF01694.20 001194302.1_29624001_1 - 9.4e-07 28.8 4.2 1.6e-06 28.1 4.2 1.4 1 0 0 1 1 1 1 Rhomboid family UBA PF00627.29 001194302.1_29624001_1 - 2.9e-06 26.9 0.0 5.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Polyketide_cyc PF03364.18 001195786.1_29622001_1 - 8.2e-23 80.9 0.0 1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1857 PF08982.9 001195786.1_29622001_1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) FGF PF00167.16 001193950.1_29627001_3 - 1e-47 161.2 2.5 1.5e-47 160.7 2.5 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 001193950.1_29627001_3 - 0.0091 16.1 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 1 Fascin domain IQ PF00612.25 001267599.2_29623001_2 - 3e-05 23.3 0.7 5.7e-05 22.4 0.7 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Pkinase_Tyr PF07714.15 001204800.2_29627001_3 - 1.9e-57 194.4 0.0 3.3e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.5 001204800.2_29627001_3 - 3.5e-55 184.4 8.2 2.8e-16 59.7 0.3 6.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001204800.2_29627001_3 - 7.6e-50 166.6 27.0 1.3e-10 41.5 0.2 8.4 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.28 001204800.2_29627001_3 - 2.1e-48 160.6 28.3 1.1e-06 28.7 0.0 11.2 12 0 0 12 12 11 8 Ankyrin repeat Pkinase PF00069.23 001204800.2_29627001_3 - 4.7e-46 157.1 0.0 1.4e-45 155.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ank_3 PF13606.4 001204800.2_29627001_3 - 2.7e-41 134.7 15.8 0.00025 21.1 0.1 11.5 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.4 001204800.2_29627001_3 - 7.6e-38 127.8 12.1 7.2e-09 35.6 0.1 9.3 1 1 9 10 10 10 8 Ankyrin repeats (many copies) Kinase-like PF14531.4 001204800.2_29627001_3 - 0.044 13.0 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.21 001204800.2_29627001_3 - 0.053 13.3 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.12 001204800.2_29627001_3 - 0.063 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001204800.2_29627001_3 - 0.065 12.7 1.5 0.16 11.4 0.1 2.1 2 0 0 2 2 2 0 RIO1 family NUDIX PF00293.26 001194315.1_29623001_1 - 5.5e-10 39.3 0.0 9.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SNN_transmemb PF09049.8 001193439.1_29624001_3 - 3.5e-22 77.9 8.6 7.2e-22 76.9 8.6 1.6 1 0 0 1 1 1 1 Stannin transmembrane SNN_linker PF09050.8 001193439.1_29624001_3 - 1.2e-19 69.6 2.0 2e-19 68.9 2.0 1.3 1 0 0 1 1 1 1 Stannin unstructured linker SNN_cytoplasm PF09051.8 001193439.1_29624001_3 - 8.3e-18 63.8 0.2 1.7e-17 62.7 0.2 1.6 1 0 0 1 1 1 1 Stannin cytoplasmic Vac_ImportDeg PF09783.7 001193962.1_29629001_1 - 7.5e-61 204.5 4.4 1e-60 204.1 4.4 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein 7tm_1 PF00001.19 001194365.1_29623001_3 - 1.8e-26 92.8 21.4 2.9e-26 92.2 21.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4044 PF13253.4 001194365.1_29623001_3 - 0.32 10.4 5.2 0.83 9.1 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) 7tm_4 PF13853.4 001194566.1_29622001_1 - 5.1e-106 354.3 16.7 5.9e-106 354.1 16.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194566.1_29622001_1 - 4.3e-17 62.1 17.3 3.2e-16 59.2 17.3 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194566.1_29622001_1 - 1.7e-09 37.3 2.7 1.7e-09 37.3 2.7 1.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001194190.1_29622001_1 - 1.7e-46 159.0 20.0 2.1e-46 158.7 20.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194190.1_29622001_1 - 3.6e-28 98.4 19.3 5.9e-28 97.7 19.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.7 001194190.1_29622001_1 - 0.0017 17.6 19.7 0.0023 17.2 19.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0542 PF15086.4 001194190.1_29622001_1 - 0.093 12.5 0.1 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF3377 PF11857.6 001194190.1_29622001_1 - 0.1 12.4 0.6 0.31 10.8 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) LIDHydrolase PF10230.7 001194777.2_29624001_1 - 2.4e-60 204.2 0.0 5e-60 203.2 0.0 1.4 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.18 001194777.2_29624001_1 - 0.064 12.7 0.0 4.5 6.7 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001194777.2_29624001_1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4518 PF15008.4 001190960.1_29622001_1 - 1.9e-109 365.0 0.0 2.2e-109 364.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) FA_desaturase PF00487.22 001194717.1_29625001_3 - 5.3e-33 114.8 29.1 5.3e-33 114.8 29.1 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.26 001194717.1_29625001_3 - 1.2e-20 73.3 0.0 2.1e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PMP22_Claudin PF00822.18 001193829.1_29622001_1 - 1.4e-32 112.7 10.9 1.6e-32 112.5 10.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001193829.1_29622001_1 - 4.8e-10 39.4 15.7 4.4e-09 36.2 15.7 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF872 PF05915.10 001193829.1_29622001_1 - 0.0042 17.2 0.5 0.0042 17.2 0.5 2.3 2 1 1 3 3 3 1 Eukaryotic protein of unknown function (DUF872) DUF2373 PF10180.7 001193747.1_29623001_1 - 6.1e-22 77.1 0.6 1e-21 76.4 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) NOT2_3_5 PF04153.16 001193747.1_29623001_1 - 0.14 12.1 0.6 0.24 11.3 0.6 1.3 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family KRAB PF01352.25 001194841.2_29624001_1 - 2.1e-21 75.2 0.0 3.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 KRAB box zf-C2H2 PF00096.24 001194841.2_29624001_1 - 1.8e-10 40.5 6.5 1.2e-05 25.4 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001194841.2_29624001_1 - 7.7e-09 35.5 2.3 1.5e-06 28.2 0.6 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.4 001194841.2_29624001_1 - 8.8e-06 26.0 6.8 0.047 14.4 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001194841.2_29624001_1 - 0.0031 17.5 1.4 0.0031 17.5 1.4 2.0 2 0 0 2 2 2 1 Zinc ribbon domain zf-C2H2_6 PF13912.4 001194841.2_29624001_1 - 0.14 12.0 3.7 3.3 7.6 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Nudix_N_2 PF14803.4 001194841.2_29624001_1 - 0.15 11.8 2.3 3.6 7.5 0.6 2.8 2 0 0 2 2 2 0 Nudix N-terminal zf-C2H2_3 PF13878.4 001194841.2_29624001_1 - 0.31 10.8 1.0 6.9 6.5 0.0 3.0 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_11 PF16622.3 001194841.2_29624001_1 - 1.3 8.7 4.2 1.6 8.5 1.3 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF758 PF05527.9 001193682.1_29622001_1 - 2e-70 236.4 0.0 2.2e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) UreF PF01730.14 001193682.1_29622001_1 - 0.029 14.8 0.9 0.043 14.3 0.9 1.3 1 0 0 1 1 1 0 UreF Enkurin PF13864.4 001193959.1_29624001_2 - 1.7e-22 79.5 0.3 1.7e-22 79.5 0.3 1.9 2 0 0 2 2 2 1 Calmodulin-binding Erf4 PF10256.7 001194104.1_29622001_2 - 1.6e-33 115.1 0.0 1.9e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family EF-hand_1 PF00036.30 001194172.2_29625001_2 - 2.6e-15 54.6 6.8 3.6e-06 26.0 0.6 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.4 001194172.2_29625001_2 - 9.7e-15 54.7 3.5 2.8e-11 43.6 1.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001194172.2_29625001_2 - 7.8e-14 50.2 5.0 2e-05 24.0 0.3 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.4 001194172.2_29625001_2 - 2.4e-13 48.8 1.0 6.2e-06 25.4 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.4 001194172.2_29625001_2 - 0.00083 18.9 12.9 0.48 10.1 0.1 3.8 4 0 0 4 4 4 3 EF-hand domain pair Spy1 PF11357.6 001194736.1_29622001_1 - 1.3e-62 209.8 3.9 1.6e-62 209.4 3.9 1.1 1 0 0 1 1 1 1 Cell cycle regulatory protein Ribosomal_L7Ae PF01248.24 001144039.1_29622001_1 - 4.4e-24 83.9 0.7 1.4e-23 82.3 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 3Beta_HSD PF01073.17 001194527.2_29626001_1 - 1.3e-67 227.6 0.0 1.8e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.19 001194527.2_29626001_1 - 1.6e-29 103.0 0.0 2.1e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001194527.2_29626001_1 - 3.8e-12 46.1 0.0 1.3e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.15 001194527.2_29626001_1 - 4.6e-11 42.2 0.0 6.3e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.13 001194527.2_29626001_1 - 4.8e-07 29.1 0.0 1.2e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.10 001194527.2_29626001_1 - 1.4e-06 27.6 0.0 2.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.4 001194527.2_29626001_1 - 1.5e-06 28.1 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.23 001194527.2_29626001_1 - 0.047 13.0 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase PALP PF00291.23 001194522.1_29624001_2 - 3.1e-72 243.3 1.2 4.2e-72 242.9 1.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Forkhead PF00250.16 001198733.1_29625001_1 - 9.3e-38 128.3 0.0 1.5e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Trp_leader2 PF08056.9 001198733.1_29625001_2 - 2.4 8.1 5.8 6.2 6.8 5.8 1.6 1 0 0 1 1 1 0 Tryptophan operon leader peptide 7tm_1 PF00001.19 001195395.1_29625001_1 - 4e-29 101.5 22.8 7.8e-29 100.6 22.8 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.4 001195395.1_29625001_1 - 1.8e-18 65.9 3.1 1.3e-05 24.8 0.3 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_5 PF13306.4 001195395.1_29625001_1 - 1.7e-11 44.1 2.0 4e-05 23.4 0.1 2.8 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) SSFA2_C PF14723.4 001195395.1_29625001_1 - 0.049 13.4 0.4 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus YcxB PF14317.4 001195395.1_29625001_1 - 0.13 11.6 0.1 3.7 6.9 0.0 3.2 4 0 0 4 4 4 0 YcxB-like protein Il2rg PF15874.3 001190834.1_29622001_1 - 2.4e-35 120.4 0.0 4.1e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain LRR_8 PF13855.4 001193750.1_29623001_3 - 1.4e-35 120.7 59.0 2e-10 40.1 4.1 4.4 1 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.5 001193750.1_29623001_3 - 5e-19 67.9 29.7 7.4e-07 29.2 0.6 6.4 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001193750.1_29623001_3 - 2.9e-11 43.1 15.1 5.9e-08 32.3 2.1 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.31 001193750.1_29623001_3 - 0.00029 20.7 29.4 1 9.9 0.0 9.0 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_2 PF07723.11 001193750.1_29623001_3 - 0.00076 19.9 0.3 0.16 12.6 0.0 3.9 3 0 0 3 3 3 1 Leucine Rich Repeat RsmF_methylt_CI PF17126.3 001193750.1_29623001_3 - 0.0095 15.8 1.0 3.8 7.5 0.1 4.1 3 1 0 3 3 3 1 RsmF rRNA methyltransferase first C-terminal domain C1q PF00386.19 001193684.1_29623001_1 - 1.6e-25 89.6 0.1 2.1e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 C1q domain TEX19 PF15553.4 001194590.1_29622001_1 - 9.8e-87 288.7 9.9 1.3e-85 285.1 5.9 2.1 2 0 0 2 2 2 2 Testis-expressed protein 19 HNF-1B_C PF04812.11 001194548.2_29626001_3 - 6.4e-123 409.1 43.7 1.1e-122 408.3 43.7 1.4 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.11 001194548.2_29626001_3 - 6e-64 216.1 0.0 6e-64 216.1 0.0 3.3 4 0 0 4 4 4 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox PF00046.27 001194548.2_29626001_3 - 2.2e-06 27.3 0.1 8.4e-06 25.4 0.1 2.0 1 1 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001194548.2_29626001_3 - 0.092 12.5 0.1 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Homeobox KN domain 7tm_1 PF00001.19 001278400.1_29623001_3 - 4.8e-53 180.0 12.6 6.1e-53 179.6 12.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001278400.1_29623001_3 - 5e-09 35.8 11.1 7.6e-09 35.2 11.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.7 001278400.1_29623001_3 - 1.7e-07 30.7 7.5 2.9e-07 30.0 7.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.7 001278400.1_29623001_3 - 0.00056 19.2 8.6 0.00056 19.2 8.6 2.2 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.7 001278400.1_29623001_3 - 0.66 9.1 14.1 1.4 8.1 12.9 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw TOH_N PF12549.6 001195299.1_29623001_2 - 0.094 12.5 3.8 0.3 10.9 3.8 1.9 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal SCAMP PF04144.11 001195299.1_29623001_3 - 3.8e-70 235.6 12.7 5.2e-70 235.2 12.7 1.2 1 0 0 1 1 1 1 SCAMP family KfrA_N PF11740.6 001195299.1_29623001_3 - 0.014 15.9 2.0 0.014 15.9 2.0 1.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF3552 PF12072.6 001195299.1_29623001_3 - 0.039 13.2 0.9 0.061 12.6 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Myb_DNA-bind_5 PF13873.4 001193947.1_29623001_3 - 1.6e-24 85.6 2.0 3.2e-24 84.6 2.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.7 001193947.1_29623001_3 - 0.0025 18.0 0.6 0.0068 16.6 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_S68 PF10461.7 001193947.1_29623001_3 - 0.098 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase S68 HTH_Tnp_1 PF01527.18 001194898.1_29625001_3 - 1.3e-10 41.3 9.9 4.9e-06 26.6 0.1 5.8 6 0 0 6 6 6 2 Transposase HTH_23 PF13384.4 001194898.1_29625001_3 - 2.7e-08 33.2 5.3 0.0024 17.5 0.3 4.5 4 0 0 4 4 4 2 Homeodomain-like domain HTH_Tnp_1_2 PF13022.4 001194898.1_29625001_3 - 3e-06 27.2 2.0 0.16 12.0 0.0 4.1 4 0 0 4 4 4 2 Helix-turn-helix of insertion element transposase DUF1492 PF07374.9 001194898.1_29625001_3 - 0.0012 18.9 2.6 7.2 6.7 0.0 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1492) HTH_36 PF13730.4 001194898.1_29625001_3 - 0.0061 16.4 0.1 7.6 6.5 0.0 4.3 5 0 0 5 5 5 1 Helix-turn-helix domain HTH_28 PF13518.4 001194898.1_29625001_3 - 0.014 15.4 9.7 0.71 9.9 0.1 4.6 5 0 0 5 5 5 0 Helix-turn-helix domain HTH_29 PF13551.4 001194898.1_29625001_3 - 0.019 14.9 2.4 0.18 11.7 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn helix HTH_17 PF12728.5 001194898.1_29625001_3 - 0.083 13.0 4.1 6 7.0 0.1 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_7 PF02796.13 001194898.1_29625001_3 - 0.1 12.5 0.8 0.42 10.6 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cnl2_NKP2 PF09447.8 001194898.1_29625001_3 - 0.35 10.9 2.6 19 5.4 0.2 3.9 4 0 0 4 4 4 0 Cnl2/NKP2 family protein DUF3504 PF12012.6 001194796.1_29625001_2 - 1.1e-36 126.1 0.2 1.9e-36 125.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) STN PF07660.12 001194796.1_29625001_2 - 0.17 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain SNARE PF05739.17 001194798.1_29625001_3 - 0.00014 21.6 0.1 0.00029 20.7 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Phage_holin_3_6 PF07332.9 001194798.1_29625001_3 - 0.021 14.7 0.6 0.049 13.5 0.6 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Herpes_TK_C PF08465.8 001194798.1_29625001_3 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal Gly-zipper_YMGG PF13441.4 001194798.1_29625001_3 - 5.4 6.7 14.3 8.8 6.0 14.3 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper ALG11_N PF15924.3 001190890.1_29623001_1 - 8.2e-92 306.8 0.2 1.1e-91 306.4 0.2 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.18 001190890.1_29623001_1 - 1.2e-27 96.4 0.0 2.3e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001190890.1_29623001_1 - 2.1e-15 57.2 0.0 3.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.4 001190890.1_29623001_1 - 0.00045 20.4 0.0 0.00089 19.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 7tm_4 PF13853.4 001194398.1_29623001_3 - 6.3e-47 160.5 14.2 7.8e-47 160.2 14.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194398.1_29623001_3 - 2.7e-25 89.0 15.0 2.7e-25 89.0 15.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194398.1_29623001_3 - 8.9e-05 21.9 10.0 0.00015 21.1 10.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001194398.1_29623001_3 - 0.00045 19.5 7.6 0.0011 18.3 7.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Claudin_3 PF06653.9 001193849.1_29623001_3 - 0.0015 18.4 3.5 0.48 10.2 0.1 2.3 2 0 0 2 2 2 2 Tight junction protein, Claudin-like L_HMGIC_fpl PF10242.7 001193849.1_29623001_3 - 0.014 15.5 3.7 0.018 15.1 1.1 2.3 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.18 001193849.1_29623001_3 - 0.048 13.4 0.6 0.048 13.4 0.6 2.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.10 001193849.1_29623001_3 - 0.055 12.8 0.4 0.11 11.8 0.4 1.5 1 0 0 1 1 1 0 Clc-like Humanin PF15040.4 001195093.1_29624001_3 - 2.6e-16 58.6 0.8 4.4e-16 57.9 0.8 1.4 1 0 0 1 1 1 1 Humanin family EB1 PF03271.15 001194273.1_29623001_2 - 0.2 11.8 0.7 45 4.3 0.8 3.2 3 0 0 3 3 3 0 EB1-like C-terminal motif p450 PF00067.20 001195758.1_29624001_1 - 1.1e-128 429.8 1.1 1.2e-128 429.6 1.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 TMEM108 PF15759.3 001194719.1_29621001_2 - 0.79 8.4 7.4 0.94 8.1 7.4 1.1 1 0 0 1 1 1 0 TMEM108 family 3Beta_HSD PF01073.17 001193445.1_29621001_1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WAP PF00095.19 001193445.1_29621001_1 - 0.045 14.0 10.9 0.058 13.7 10.9 1.2 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Roc PF08477.11 001194410.1_29624001_2 - 1.4e-13 51.0 0.0 2.1e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 001194410.1_29624001_2 - 6.4e-10 38.7 0.0 9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.19 001194410.1_29624001_2 - 2e-07 30.5 0.0 2.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001194410.1_29624001_2 - 3.3e-05 23.3 0.0 5.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001194410.1_29624001_2 - 0.0089 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.18 001194410.1_29624001_2 - 0.01 14.9 0.0 0.58 9.1 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.7 001194410.1_29624001_2 - 0.06 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Cep57_MT_bd PF06657.11 001194410.1_29624001_2 - 0.14 12.5 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Ras PF00071.20 001194269.1_29623001_3 - 4e-60 202.0 0.2 4.9e-60 201.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001194269.1_29623001_3 - 1.3e-32 112.4 0.3 1.8e-32 112.0 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001194269.1_29623001_3 - 3.1e-12 46.2 0.1 4.1e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001194269.1_29623001_3 - 0.00098 18.5 0.1 0.0025 17.1 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001194269.1_29623001_3 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001194269.1_29623001_3 - 0.0027 17.7 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001194269.1_29623001_3 - 0.0064 15.9 0.0 0.014 14.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.16 001194269.1_29623001_3 - 0.059 12.8 0.0 4.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.14 001194269.1_29623001_3 - 0.099 12.4 0.0 7 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.4 001194269.1_29623001_3 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MORN PF02493.18 001194378.1_29622001_1 - 0.083 12.7 1.6 0.19 11.6 1.6 1.6 1 0 0 1 1 1 0 MORN repeat PsbN PF02468.13 001194378.1_29622001_1 - 0.22 11.3 0.2 0.22 11.3 0.2 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DnaJ PF00226.29 001194448.1_29624001_2 - 6.5e-18 64.5 0.1 1.2e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain TM2 PF05154.14 001194448.1_29624001_2 - 4.7e-07 29.9 10.8 4.7e-07 29.9 10.8 2.1 2 0 0 2 2 2 1 TM2 domain Ten_N PF06484.10 001193929.1_29629001_2 - 2.5e-160 534.3 28.0 1.4e-89 301.4 8.5 2.2 1 1 1 2 2 2 2 Teneurin Intracellular Region Tox-GHH PF15636.4 001193929.1_29629001_2 - 2e-31 107.5 1.4 3.8e-31 106.7 1.4 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.11 001193929.1_29629001_2 - 4.8e-14 52.3 179.8 0.00063 19.9 12.0 10.0 10 0 0 10 10 10 8 EGF-like domain RHS_repeat PF05593.12 001193929.1_29629001_2 - 1.6e-13 50.7 32.0 0.0043 17.4 0.1 10.2 9 1 2 11 11 11 4 RHS Repeat NHL PF01436.19 001193929.1_29629001_2 - 1.4e-06 27.9 1.8 0.39 10.7 0.0 5.8 5 0 0 5 5 5 2 NHL repeat CarboxypepD_reg PF13620.4 001193929.1_29629001_2 - 0.02 15.0 0.3 0.095 12.8 0.0 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Band_7 PF01145.23 001193787.1_29623001_3 - 2.5e-29 102.4 2.6 3.1e-29 102.1 2.6 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family MazG-like PF12643.5 001194491.1_29623001_2 - 3e-09 36.9 0.0 4.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 MazG-like family MazG PF03819.15 001194491.1_29623001_2 - 8.8e-06 25.7 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Tmemb_170 PF10190.7 001194844.1_29623001_3 - 3.5e-40 136.5 7.1 5.4e-40 135.9 7.1 1.3 1 0 0 1 1 1 1 Putative transmembrane protein 170 MRP-63 PF14978.4 001193743.2_29622001_1 - 1.4e-36 124.9 0.8 1.7e-36 124.6 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 ICAM_N PF03921.12 001195749.1_29624001_1 - 1.7e-34 117.2 0.1 2.8e-33 113.3 0.0 2.8 3 0 0 3 3 3 1 Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 PF13895.4 001195749.1_29624001_1 - 4.2e-15 55.7 0.3 0.00083 19.5 0.0 4.5 5 0 0 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.4 001195749.1_29624001_1 - 8.2e-10 39.0 2.1 0.016 15.7 0.3 4.5 4 1 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.10 001195749.1_29624001_1 - 4e-08 33.1 0.4 0.033 14.1 0.1 4.5 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain I-set PF07679.14 001195749.1_29624001_1 - 0.0014 18.5 0.1 13 5.8 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin I-set domain ig PF00047.23 001195749.1_29624001_1 - 0.0046 17.0 7.7 7.1 6.7 0.1 5.5 6 1 0 6 6 6 2 Immunoglobulin domain V-set PF07686.15 001195749.1_29624001_1 - 2 8.5 4.5 23 5.0 0.1 4.3 5 2 1 6 6 6 0 Immunoglobulin V-set domain FYVE_2 PF02318.14 001190966.1_29621001_1 - 4.8e-11 42.8 6.0 5.3e-11 42.6 6.0 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger DUF3725 PF12523.6 001190966.1_29621001_1 - 0.066 13.4 0.8 0.066 13.4 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) Transcrip_reg PF01709.18 001194703.1_29623001_3 - 9.8e-62 208.4 0.0 1.1e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator DDE_1 PF03184.17 001194837.1_29624001_1 - 1e-37 129.3 0.3 1.6e-37 128.6 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.14 001194837.1_29624001_1 - 8.6e-15 54.4 0.0 1.7e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.11 001194837.1_29624001_1 - 2.9e-11 42.7 0.5 4.2e-10 39.0 0.1 2.5 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.4 001194837.1_29624001_1 - 0.0039 16.8 0.0 0.016 14.8 0.0 2.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.4 001194837.1_29624001_1 - 0.005 16.8 0.0 0.037 14.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.13 001194837.1_29624001_1 - 0.0057 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.18 001194837.1_29624001_1 - 0.011 15.9 0.0 2.3 8.4 0.0 3.2 3 0 0 3 3 3 0 Transposase Mga PF05043.11 001194837.1_29624001_1 - 0.058 13.8 0.6 0.19 12.2 0.1 2.2 2 0 0 2 2 2 0 Mga helix-turn-helix domain Asn_synthase PF00733.19 001194770.2_29625001_3 - 5.3e-18 65.7 0.0 7e-06 25.8 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.4 001194770.2_29625001_3 - 9.7e-06 25.4 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain WAP PF00095.19 001168663.1_29622001_2 - 1.8e-16 60.1 39.7 3e-08 33.8 15.8 2.1 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Claudin_2 PF13903.4 001194176.1_29622001_1 - 8.8e-29 100.5 4.9 1.1e-28 100.2 4.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.18 001194176.1_29622001_1 - 1.2e-14 54.4 1.3 1.7e-14 53.9 1.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family AA_permease_C PF13906.4 001194176.1_29622001_1 - 1.1 9.3 6.4 0.45 10.5 3.5 1.9 2 0 0 2 2 2 0 C-terminus of AA_permease 7tm_1 PF00001.19 001114111.2_29623001_1 - 9.9e-57 192.1 15.4 1.3e-56 191.7 15.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001114111.2_29623001_1 - 5e-13 48.9 17.9 6.2e-13 48.6 17.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001114111.2_29623001_1 - 0.037 13.6 13.7 0.037 13.6 8.5 2.3 2 1 0 2 2 2 0 Olfactory receptor Phage_holin_3_6 PF07332.9 001114111.2_29623001_1 - 0.2 11.6 7.0 3.6 7.5 0.0 2.8 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III zinc_ribbon_12 PF11331.6 001194092.1_29625001_1 - 0.087 12.5 2.2 0.31 10.7 2.2 1.9 1 0 0 1 1 1 0 Probable zinc-ribbon domain CD225 PF04505.10 001194092.1_29625001_2 - 2.9e-19 68.8 0.5 2e-18 66.2 0.1 2.3 2 0 0 2 2 2 1 Interferon-induced transmembrane protein LLC1 PF14945.4 001193772.2_29622001_2 - 1.3e-48 164.3 0.1 1.8e-48 163.9 0.1 1.2 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein FBPase PF00316.18 001193652.1_29623001_1 - 4.9e-83 277.2 0.1 6.3e-83 276.8 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.23 001193652.1_29623001_1 - 0.00035 20.0 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family p450 PF00067.20 001193748.1_29624001_1 - 1.5e-107 360.1 0.0 1.9e-107 359.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Homeobox PF00046.27 001194111.1_29625001_3 - 2.3e-20 72.0 3.1 3.7e-20 71.3 3.1 1.3 1 0 0 1 1 1 1 Homeobox domain 7tm_4 PF13853.4 001194430.1_29622001_1 - 1.2e-57 195.7 18.0 1.4e-57 195.4 18.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194430.1_29622001_1 - 2.3e-19 69.5 23.3 7.6e-19 67.8 23.3 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FtsX PF02687.19 001194430.1_29622001_1 - 0.17 11.7 6.4 0.086 12.7 0.5 2.5 2 0 0 2 2 2 0 FtsX-like permease family HD_3 PF13023.4 001194872.2_29622001_2 - 4.1e-28 98.2 3.9 4.8e-15 55.7 1.3 2.2 1 1 1 2 2 2 2 HD domain TMEM40 PF15817.3 001194872.2_29622001_2 - 0.12 12.0 2.6 0.2 11.2 2.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 40 family p450 PF00067.20 001194539.1_29624001_3 - 5.5e-123 411.0 0.0 6.5e-123 410.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MAGE_N PF12440.6 001193982.1_29623001_1 - 6.7e-22 77.8 0.9 6.7e-22 77.8 0.9 2.1 2 0 0 2 2 2 1 Melanoma associated antigen family N terminal MAGE PF01454.17 001193982.1_29623001_1 - 2.4e-20 73.0 0.0 1.7e-18 67.0 0.0 2.2 1 1 0 1 1 1 1 MAGE family Occludin_ELL PF07303.11 001194595.1_29623001_2 - 1.4e-24 86.6 0.0 1.8e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Occludin homology domain DUF2475 PF10629.7 001193808.1_29622001_1 - 2.5e-31 107.6 1.7 2.5e-31 107.6 1.7 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2475) Complex1_LYR PF05347.13 001194164.1_29622001_2 - 2.5e-11 43.3 1.4 4.8e-11 42.4 1.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.4 001194164.1_29622001_2 - 9e-08 32.5 6.0 2.2e-06 28.0 0.3 2.2 1 1 1 2 2 2 2 Complex1_LYR-like Complex1_LYR_2 PF13233.4 001194164.1_29622001_2 - 0.012 16.2 0.2 0.02 15.5 0.2 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Cyt-b5 PF00173.26 001193968.1_29623001_3 - 7e-11 42.0 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-RING_2 PF13639.4 001194615.2_29625001_1 - 5.3e-06 26.5 6.0 1.7e-05 24.9 6.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 001194615.2_29625001_1 - 5.4e-05 23.3 5.1 0.00011 22.2 5.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001194615.2_29625001_1 - 0.002 17.8 5.8 0.0049 16.6 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001194615.2_29625001_1 - 0.0045 16.8 6.5 0.011 15.5 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.4 001194615.2_29625001_1 - 0.014 15.1 6.8 0.042 13.6 6.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.5 001194615.2_29625001_1 - 0.019 14.9 4.0 0.047 13.6 4.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.3 001194615.2_29625001_1 - 0.033 13.7 3.9 0.11 12.0 3.9 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.3 001194615.2_29625001_1 - 0.041 13.5 3.8 0.13 11.9 3.8 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.4 001194615.2_29625001_1 - 0.055 13.4 2.1 0.16 11.9 1.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-UDP PF14569.4 001194615.2_29625001_1 - 0.51 10.4 3.2 1.3 9.1 3.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger FANCL_C PF11793.6 001194615.2_29625001_1 - 0.82 9.8 7.5 7.3 6.7 7.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.4 001194615.2_29625001_1 - 4 7.3 12.2 0.052 13.3 4.6 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 FGF PF00167.16 001194186.1_29623001_3 - 8.1e-40 135.7 0.7 1.2e-39 135.2 0.7 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Ig_3 PF13927.4 001302666.1_29623001_1 - 3.2e-08 33.9 0.3 0.00021 21.7 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 001302666.1_29623001_1 - 3.3e-08 33.6 1.0 0.0011 19.2 0.3 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001302666.1_29623001_1 - 2.8e-06 27.3 0.0 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.23 001302666.1_29623001_1 - 4.4e-06 26.6 0.4 0.059 13.4 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001302666.1_29623001_1 - 0.00047 20.0 0.0 0.052 13.5 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin I-set domain FixQ PF05545.9 001302666.1_29623001_1 - 3.9 7.4 4.8 0.77 9.6 0.1 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ OTU PF02338.17 001193698.1_29622001_1 - 3e-28 98.7 0.9 2.5e-27 95.8 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.7 001193698.1_29622001_1 - 9.6e-06 25.1 4.9 0.0003 20.2 0.0 3.3 2 1 0 2 2 2 1 Peptidase C65 Otubain YqzH PF14164.4 001193698.1_29622001_1 - 0.1 12.6 0.5 5.9 6.9 0.5 3.3 3 0 0 3 3 3 0 YqzH-like protein LCD1 PF09798.7 001193698.1_29622001_1 - 0.12 10.8 4.5 0.12 10.7 4.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Herpes_U34 PF04541.11 001193698.1_29622001_1 - 0.14 11.3 0.6 0.25 10.4 0.6 1.4 1 0 0 1 1 1 0 Herpesvirus virion protein U34 HisKA PF00512.23 001193698.1_29622001_1 - 0.26 11.2 0.0 0.26 11.2 0.0 2.9 2 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Presenilin PF01080.15 001193698.1_29622001_1 - 0.58 8.7 2.4 0.66 8.5 2.4 1.1 1 0 0 1 1 1 0 Presenilin FlxA PF14282.4 001193698.1_29622001_1 - 2.2 8.2 20.5 0.063 13.1 12.7 2.1 1 1 1 2 2 2 0 FlxA-like protein DUF4407 PF14362.4 001193698.1_29622001_1 - 6.1 6.0 11.0 8 5.6 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLX9 PF15341.4 001193698.1_29622001_1 - 8.1 6.8 23.4 40 4.5 23.3 1.9 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Methyltransf_22 PF13383.4 001193830.1_29623001_1 - 9.9e-11 41.6 0.2 1.3e-10 41.2 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.10 001193830.1_29623001_1 - 7.5e-06 25.9 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Homeobox PF00046.27 001194756.2_29624001_3 - 7.5e-22 76.8 8.1 1.4e-21 75.9 8.1 1.5 1 0 0 1 1 1 1 Homeobox domain DUF2209 PF09974.7 001194756.2_29624001_3 - 0.065 13.4 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) COMM_domain PF07258.12 001194418.1_29628001_1 - 3.9e-18 65.2 1.0 8.4e-18 64.1 1.0 1.6 1 0 0 1 1 1 1 COMM domain 7tm_4 PF13853.4 001194427.1_29623001_3 - 4e-41 141.5 16.9 4.8e-41 141.2 16.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194427.1_29623001_3 - 2.1e-21 76.3 14.2 4.6e-21 75.1 14.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SLC3A2_N PF16028.3 001194427.1_29623001_3 - 0.42 10.1 2.7 1.7 8.1 0.5 2.4 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus SK_channel PF03530.12 001194427.1_29623001_3 - 2.1 8.2 7.1 0.38 10.6 0.6 2.5 2 1 0 2 2 2 0 Calcium-activated SK potassium channel 7tm_4 PF13853.4 001193869.1_29623001_1 - 4.1e-43 148.0 12.6 5.3e-43 147.6 12.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001193869.1_29623001_1 - 3e-21 75.7 11.5 3e-21 75.7 11.5 1.8 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) PMP22_Claudin PF00822.18 001194829.1_29622001_1 - 1.3e-46 158.4 13.2 1.5e-46 158.2 13.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001194829.1_29622001_1 - 3.6e-08 33.3 10.7 3.6e-08 33.3 10.7 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.9 001194829.1_29622001_1 - 0.00096 19.0 14.2 0.0058 16.4 14.1 2.2 1 1 1 2 2 2 1 Tight junction protein, Claudin-like DUF3377 PF11857.6 001194829.1_29622001_1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) DUF2569 PF10754.7 001194829.1_29622001_1 - 0.3 11.4 8.8 0.054 13.8 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) YdjO PF14169.4 001194829.1_29622001_1 - 0.66 9.6 3.9 3.4 7.4 2.6 2.1 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-DHHC PF01529.18 001194829.1_29622001_1 - 3.7 7.5 13.4 3.7 7.5 7.6 2.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF1772 PF08592.9 001194829.1_29622001_1 - 8.2 6.6 12.6 0.13 12.4 2.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) SH3_9 PF14604.4 001194695.1_29624001_2 - 8.3e-16 57.5 2.7 3.3e-11 42.7 0.1 3.6 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.15 001194695.1_29624001_2 - 1.5e-14 53.2 3.2 4.7e-07 29.3 0.2 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.26 001194695.1_29624001_2 - 1.3e-13 50.2 3.8 2.2e-13 49.4 0.2 2.9 3 0 0 3 3 3 1 SH3 domain C1_1 PF00130.20 001194695.1_29624001_2 - 3.9e-09 36.1 11.4 6.5e-09 35.4 11.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) STAC2_u1 PF16664.3 001194695.1_29624001_2 - 8.7e-09 35.8 0.9 1.6e-08 34.9 0.1 1.8 2 0 0 2 2 2 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 C1_2 PF03107.14 001194695.1_29624001_2 - 0.01 16.0 5.0 0.019 15.1 5.0 1.4 1 0 0 1 1 1 0 C1 domain PHD PF00628.27 001194695.1_29624001_2 - 0.41 10.4 7.4 0.8 9.5 7.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.9 001194695.1_29624001_2 - 0.97 9.7 8.0 1.7 8.9 8.0 1.4 1 0 0 1 1 1 0 RING-like domain C2-set_2 PF08205.10 001194706.2_29623001_2 - 0.08 12.9 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Syndecan PF01034.18 001194706.2_29623001_2 - 0.43 10.4 1.6 0.82 9.5 1.6 1.4 1 0 0 1 1 1 0 Syndecan domain PMP22_Claudin PF00822.18 001194152.1_29625001_2 - 2.8e-30 105.2 7.6 4.3e-30 104.6 7.6 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001194152.1_29625001_2 - 4e-07 29.8 8.7 8e-07 28.9 8.7 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Glyco_transf_8 PF01501.18 001194076.2_29626001_1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 LIX1 PF14954.4 001194032.1_29627001_3 - 4.2e-128 425.7 0.1 5.3e-128 425.4 0.1 1.1 1 0 0 1 1 1 1 Limb expression 1 RasGEF PF00617.17 001194158.2_29629001_2 - 6.7e-50 169.5 0.7 1.1e-49 168.7 0.7 1.4 1 0 0 1 1 1 1 RasGEF domain DEP PF00610.19 001194158.2_29629001_2 - 1.3e-14 53.9 0.2 4.2e-14 52.2 0.2 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.18 001194158.2_29629001_2 - 1.9e-12 47.2 0.5 5.4e-12 45.8 0.5 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.21 001194158.2_29629001_2 - 0.0043 17.5 0.2 0.027 15.0 0.0 2.4 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain adh_short PF00106.23 001199126.1_29624001_1 - 5.6e-36 123.7 0.5 8e-36 123.2 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001199126.1_29624001_1 - 4e-29 101.7 0.3 6.5e-29 101.0 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.15 001199126.1_29624001_1 - 6.9e-25 87.4 0.2 1.3e-24 86.5 0.2 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.8 001199126.1_29624001_1 - 8.6e-05 22.4 1.1 0.00014 21.6 0.2 1.8 2 0 0 2 2 2 1 KR domain Alkyl_sulf_C PF14864.4 001199126.1_29624001_1 - 0.0019 18.4 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal NAD_binding_3 PF03447.14 001199126.1_29624001_1 - 0.044 14.3 1.0 12 6.4 0.1 2.3 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.13 001199126.1_29624001_1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CFC PF09443.8 001190851.1_29622001_1 - 1.5e-15 56.6 11.3 4.6e-15 55.0 11.3 1.9 1 0 0 1 1 1 1 Cripto_Frl-1_Cryptic (CFC) EGF_2 PF07974.11 001190851.1_29622001_1 - 0.00082 19.6 8.2 0.00082 19.6 8.2 2.1 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.5 001190851.1_29622001_1 - 0.0045 17.5 5.3 0.0045 17.5 5.3 2.8 3 0 0 3 3 3 1 Human growth factor-like EGF EGF PF00008.25 001190851.1_29622001_1 - 0.012 15.8 6.0 0.012 15.8 6.0 2.5 2 1 0 2 2 2 0 EGF-like domain PYRIN PF02758.14 001193432.1_29621001_1 - 1.3e-17 63.6 0.3 1.8e-17 63.2 0.3 1.2 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain DUF1831 PF08866.8 001193432.1_29621001_1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative amino acid metabolism Lebercilin PF15619.4 001193957.1_29622001_1 - 0.0014 18.2 11.4 0.0014 18.2 11.4 3.0 1 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.10 001193957.1_29622001_1 - 0.0038 17.1 23.5 0.014 15.2 7.1 3.3 1 1 1 3 3 3 2 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.17 001193957.1_29622001_1 - 0.013 13.2 32.3 0.018 12.7 32.3 1.2 1 0 0 1 1 1 0 Myosin tail Cnn_1N PF07989.9 001193957.1_29622001_1 - 0.014 15.4 9.5 0.014 15.4 9.5 4.5 1 1 1 2 2 1 0 Centrosomin N-terminal motif 1 Spc7 PF08317.9 001193957.1_29622001_1 - 0.022 13.5 35.8 0.24 10.1 11.5 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.10 001193957.1_29622001_1 - 0.029 13.6 6.7 0.27 10.5 3.6 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein FliD_C PF07195.10 001193957.1_29622001_1 - 0.034 13.4 0.8 0.034 13.4 0.8 3.7 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Filament PF00038.19 001193957.1_29622001_1 - 0.036 13.5 33.8 0.43 10.0 10.8 3.2 1 1 2 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.10 001193957.1_29622001_1 - 0.053 13.5 38.6 0.026 14.5 8.3 4.0 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.7 001193957.1_29622001_1 - 0.11 11.8 35.3 0.026 13.8 18.3 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 ATG16 PF08614.9 001193957.1_29622001_1 - 0.16 12.0 31.2 0.032 14.3 12.2 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.7 001193957.1_29622001_1 - 0.18 11.7 37.1 0.28 11.0 13.2 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.9 001193957.1_29622001_1 - 0.29 9.9 36.6 9.1 4.9 17.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) LPP PF04728.11 001193957.1_29622001_1 - 0.36 11.1 18.6 14 6.0 0.2 5.3 5 0 0 5 5 5 0 Lipoprotein leucine-zipper Phage_GPO PF05929.9 001193957.1_29622001_1 - 0.53 9.7 24.3 0.21 11.0 8.0 2.6 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.4 001193957.1_29622001_1 - 0.6 9.3 38.1 3.5 6.8 22.0 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.8 001193957.1_29622001_1 - 0.75 9.8 30.7 0.38 10.8 11.7 3.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.6 001193957.1_29622001_1 - 0.77 8.9 28.5 0.19 10.9 11.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) CCDC-167 PF15188.4 001193957.1_29622001_1 - 0.96 9.7 25.0 2 8.7 4.7 3.7 4 0 0 4 4 3 0 Coiled-coil domain-containing protein 167 ADIP PF11559.6 001193957.1_29622001_1 - 1.8 8.5 35.7 0.22 11.4 15.2 3.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding FPP PF05911.9 001193957.1_29622001_1 - 2.1 6.4 35.1 0.073 11.2 19.4 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil HAP1_N PF04849.11 001193957.1_29622001_1 - 2.7 7.0 30.3 4.6 6.2 11.3 2.4 1 1 0 2 2 2 0 HAP1 N-terminal conserved region Mod_r PF07200.11 001193957.1_29622001_1 - 2.9 7.9 34.6 2.9 7.9 3.3 3.7 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.10 001193957.1_29622001_1 - 3.3 6.9 38.0 1.1 8.5 12.8 2.8 1 1 2 3 3 3 0 Autophagy protein Apg6 EzrA PF06160.10 001193957.1_29622001_1 - 4.1 5.3 34.6 2 6.4 9.5 2.9 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF4618 PF15397.4 001193957.1_29622001_1 - 5.2 6.3 31.7 0.076 12.3 4.8 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) IncA PF04156.12 001193957.1_29622001_1 - 6.1 6.5 33.8 0.95 9.1 15.1 2.6 1 1 0 2 2 2 0 IncA protein CENP-H PF05837.10 001193957.1_29622001_1 - 6.9 7.0 28.0 1.6 9.1 1.1 3.7 1 1 1 3 3 3 0 Centromere protein H (CENP-H) KASH_CCD PF14662.4 001193957.1_29622001_1 - 9.4 5.9 36.9 13 5.5 8.9 3.4 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH LRR_6 PF13516.4 001194038.1_29624001_2 - 5.2e-05 22.8 5.7 8.5 6.6 0.1 6.6 7 0 0 7 7 7 3 Leucine Rich repeat DUF4689 PF15755.3 001194257.1_29622001_1 - 4e-125 415.7 23.5 4.4e-125 415.5 23.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4689) PX PF00787.22 001193757.2_29628001_3 - 1.7e-25 89.1 0.1 2.6e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 PX domain Ras PF00071.20 001194854.1_29623001_1 - 2.6e-55 186.3 0.0 3.2e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001194854.1_29623001_1 - 5.7e-19 68.4 0.0 7.6e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001194854.1_29623001_1 - 2.7e-09 36.6 0.0 3.5e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001194854.1_29623001_1 - 2.1e-05 24.4 0.1 0.023 14.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001194854.1_29623001_1 - 0.00011 21.7 0.0 0.00043 19.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001194854.1_29623001_1 - 0.0014 18.5 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.3 001194854.1_29623001_1 - 0.042 13.8 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.16 001194854.1_29623001_1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B HMG_box PF00505.17 001193732.2_29626001_2 - 2.4e-27 95.0 4.9 4.2e-27 94.2 4.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001193732.2_29626001_2 - 5.9e-10 39.5 2.8 1.1e-09 38.7 2.8 1.3 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.6 001193732.2_29626001_2 - 3.3e-06 27.9 0.0 8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 SOX transcription factor FGF PF00167.16 001193911.1_29622001_1 - 5e-41 139.6 0.0 5.9e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 001193911.1_29622001_1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Fascin domain Phi_1 PF04674.10 001193911.1_29622001_2 - 0.047 12.8 2.0 0.067 12.3 2.0 1.2 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region EAF PF09816.7 001193490.1_29623001_3 - 1e-20 73.8 0.0 2.5e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Lin-8 PF03353.13 001193490.1_29623001_3 - 0.72 9.2 7.4 1 8.8 7.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.7 001193490.1_29623001_3 - 5.8 5.2 10.8 7.2 4.9 10.8 1.1 1 0 0 1 1 1 0 Transmembrane protein SBF2 PF12335.6 001194581.1_29624001_1 - 5e-05 22.9 0.7 0.00042 19.9 0.1 2.2 2 0 0 2 2 2 1 Myotubularin protein UPF0489 PF12640.5 001193783.1_29624001_2 - 3.9e-71 238.8 0.1 8.3e-71 237.8 0.1 1.6 1 1 0 1 1 1 1 UPF0489 domain TMEM117 PF15113.4 001194702.1_29623001_3 - 0.14 11.0 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 TMEM117 protein family DUF986 PF06173.10 001194702.1_29623001_3 - 0.17 11.7 2.4 0.11 12.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF986) Arm_2 PF04826.11 001193715.1_29628001_3 - 1.4e-55 188.4 4.5 2e-55 187.9 4.5 1.1 1 0 0 1 1 1 1 Armadillo-like eIF-1a PF01176.17 001194525.1_29623001_2 - 2.7e-18 65.4 0.1 4.1e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HLH PF00010.24 001193735.1_29622001_1 - 1.4e-15 56.8 0.0 3.5e-15 55.6 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.11 001193735.1_29622001_1 - 3.2e-08 33.5 0.3 7.7e-08 32.3 0.3 1.7 1 0 0 1 1 1 1 Hairy Orange TPR_10 PF13374.4 001193735.1_29622001_1 - 0.12 12.2 0.4 18 5.2 0.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat 7tm_4 PF13853.4 001194785.1_29623001_3 - 2.7e-113 378.2 24.2 3.4e-113 377.9 24.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194785.1_29623001_3 - 2.1e-21 76.2 19.2 3.9e-21 75.4 19.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194785.1_29623001_3 - 1.7e-08 34.0 18.2 3.3e-08 33.1 18.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Polysacc_synt_4 PF04669.11 001194106.1_29623001_2 - 5.1e-21 75.0 0.2 8.1e-20 71.0 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis MAJIN PF15077.4 001194106.1_29623001_3 - 0.13 12.0 7.8 0.19 11.5 7.8 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein GAS PF13851.4 001193986.1_29622001_1 - 0.00066 19.0 18.7 0.00066 19.0 18.7 2.6 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding FUSC PF04632.10 001193986.1_29622001_1 - 0.31 9.4 1.3 0.79 8.1 0.1 1.8 1 1 0 2 2 2 0 Fusaric acid resistance protein family Fungal_trans_2 PF11951.6 001193986.1_29622001_1 - 0.55 8.8 8.6 0.035 12.8 2.9 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain ApoO PF09769.7 001193986.1_29622001_1 - 1.4 8.8 6.6 2.5 7.9 0.2 2.9 1 1 1 3 3 3 0 Apolipoprotein O TPR_MLP1_2 PF07926.10 001193986.1_29622001_1 - 1.4 8.8 33.6 0.14 12.1 13.9 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1192 PF06698.9 001193986.1_29622001_1 - 2.4 8.1 12.9 0.41 10.6 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) LPP PF04728.11 001193986.1_29622001_1 - 3.7 7.9 8.3 2 8.7 0.9 3.5 2 2 1 3 3 3 0 Lipoprotein leucine-zipper F5_F8_type_C PF00754.23 001194911.1_29622001_3 - 1.2e-26 93.2 0.3 1.8e-26 92.6 0.3 1.2 1 0 0 1 1 1 1 F5/8 type C domain Lyase_N PF09092.9 001194911.1_29622001_3 - 0.081 12.7 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Lyase, N terminal DUF423 PF04241.13 001194393.1_29621001_3 - 1.9e-17 63.1 0.8 3.4e-17 62.3 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Mog1 PF04603.10 001194570.1_29622001_1 - 5.9e-38 130.2 0.0 7.3e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein CENP-M PF11111.6 001194334.1_29622001_1 - 5.6e-81 269.7 0.9 5.6e-81 269.7 0.9 1.5 2 0 0 2 2 2 1 Centromere protein M (CENP-M) COX7B PF05392.9 001193385.1_29621001_3 - 2.1e-42 142.5 0.1 2.7e-42 142.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB TMEM189_B_dmain PF10520.7 001194059.2_29625001_3 - 1.8e-76 256.1 1.8 2.5e-76 255.6 1.8 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain GIY-YIG PF01541.22 001194449.1_29623001_3 - 1.3e-12 47.7 0.0 3.4e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.6 001194449.1_29623001_3 - 0.021 14.8 6.4 0.043 13.9 6.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Interferon PF00143.17 001194367.2_29622001_1 - 9.7e-67 224.0 1.6 1.2e-66 223.7 1.6 1.1 1 0 0 1 1 1 1 Interferon alpha/beta domain DUF1039 PF06287.9 001194246.1_29623001_1 - 0.071 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) CBM_20 PF00686.17 001194876.1_29625001_3 - 1.3e-18 66.6 0.6 2.5e-18 65.7 0.6 1.5 1 0 0 1 1 1 1 Starch binding domain Keratin_matx PF04579.10 001193398.1_29622001_1 - 1.6e-48 162.9 34.9 2.1e-48 162.4 34.9 1.2 1 0 0 1 1 1 1 Keratin, high-sulphur matrix protein DUF4642 PF15484.4 001194779.1_29622001_1 - 1.4e-77 259.1 4.0 1.7e-77 258.8 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4642) ECSCR PF15820.3 001194779.1_29622001_1 - 0.04 13.6 0.1 0.076 12.7 0.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator CD34_antigen PF06365.10 001194779.1_29622001_1 - 0.078 12.4 2.3 0.13 11.8 0.3 2.0 1 1 1 2 2 2 0 CD34/Podocalyxin family DUF912 PF06024.10 001194779.1_29622001_1 - 0.81 9.9 4.0 0.57 10.4 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LRR_8 PF13855.4 001194240.1_29622001_1 - 1.5e-18 66.2 0.3 1.7e-12 46.8 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRRNT PF01462.16 001194240.1_29622001_1 - 6.8e-08 31.9 3.4 2.1e-07 30.3 3.4 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.31 001194240.1_29622001_1 - 1.8e-07 30.5 0.4 0.45 11.0 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.5 001194240.1_29622001_1 - 2.3e-06 27.7 0.0 1.5e-05 25.1 0.0 2.4 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.4 001194240.1_29622001_1 - 0.00032 20.4 0.9 0.093 12.7 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeat Adipogenin PF15202.4 001193372.1_29622001_2 - 3.5e-49 164.6 3.5 5.1e-49 164.1 3.5 1.3 1 0 0 1 1 1 1 Adipogenin PSP94 PF05825.9 001193770.1_29622001_2 - 6.1e-07 29.8 2.9 1e-06 29.1 2.9 1.3 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) TILa PF12714.5 001193770.1_29622001_2 - 0.0078 16.0 4.5 0.0078 16.0 4.5 2.0 2 0 0 2 2 2 1 TILa domain DUF3040 PF11239.6 001193770.1_29622001_2 - 0.13 12.5 0.5 0.2 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) 7tm_4 PF13853.4 001194549.1_29622001_1 - 1.9e-46 158.9 16.3 2.4e-46 158.6 16.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194549.1_29622001_1 - 4.1e-21 75.3 20.7 8.1e-21 74.3 20.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194549.1_29622001_1 - 0.00055 19.3 15.8 0.0013 18.1 15.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx V-set PF07686.15 001193935.1_29626001_3 - 9.2e-09 35.3 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001193935.1_29626001_3 - 6e-08 33.1 0.8 2.3e-07 31.2 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.14 001193935.1_29626001_3 - 1.5e-07 31.2 0.7 8.5e-07 28.8 0.7 2.1 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.23 001193935.1_29626001_3 - 1.3e-06 28.4 0.0 4.3e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001193935.1_29626001_3 - 0.016 15.4 0.5 0.81 9.9 0.1 3.0 2 1 0 2 2 2 0 Immunoglobulin domain Methyltransf_23 PF13489.4 001195823.1_29622001_3 - 9e-18 64.6 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001195823.1_29622001_3 - 1.7e-07 31.7 0.0 3.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001195823.1_29622001_3 - 1e-05 25.2 0.1 6.6e-05 22.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.7 001195823.1_29622001_3 - 0.0069 16.0 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase V-set PF07686.15 001194390.1_29623001_3 - 9.3e-08 32.1 0.1 1.7e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 001194390.1_29623001_3 - 3.1e-06 27.1 0.0 5.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001194390.1_29623001_3 - 4.1e-06 27.2 0.0 9.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001194390.1_29623001_3 - 0.0028 17.6 0.0 0.0079 16.1 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain 7tm_4 PF13853.4 001194088.1_29623001_2 - 5.2e-46 157.5 19.2 6.8e-46 157.1 19.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194088.1_29623001_2 - 1.1e-14 54.2 23.5 7e-14 51.6 23.5 2.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194088.1_29623001_2 - 0.00017 20.9 20.9 0.0013 18.0 20.9 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SLC3A2_N PF16028.3 001194088.1_29623001_2 - 0.013 14.9 5.7 0.29 10.6 0.2 2.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF4569 PF15133.4 001194018.1_29624001_3 - 1.6e-105 353.0 13.8 1.9e-105 352.7 13.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) FGF PF00167.16 001194613.1_29629001_3 - 2.6e-47 159.9 1.9 4e-47 159.3 1.9 1.3 1 0 0 1 1 1 1 Fibroblast growth factor Band_7 PF01145.23 001194366.1_29627001_1 - 7.8e-20 71.5 0.1 1.2e-19 70.9 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Catalase-rel PF06628.10 001194366.1_29627001_1 - 0.092 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Catalase-related immune-responsive DUF4346 PF14251.4 001194366.1_29627001_1 - 0.1 12.5 2.3 0.24 11.3 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) PNISR PF15996.3 001194366.1_29627001_1 - 0.78 9.7 8.1 1.1 9.2 8.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CAAP1 PF15335.4 001194328.1_29625001_1 - 2.6e-27 95.0 10.2 4.8e-27 94.1 10.2 1.5 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 Ribosomal_L32p PF01783.21 001194328.1_29625001_1 - 0.22 11.7 2.6 0.76 9.9 0.3 2.3 2 0 0 2 2 2 0 Ribosomal L32p protein family Ribosomal_L17 PF01196.17 001193734.1_29625001_3 - 2.1e-24 86.1 0.0 3.4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 7tm_4 PF13853.4 001194102.1_29622001_1 - 8.7e-55 186.3 14.3 1e-54 186.0 14.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194102.1_29622001_1 - 7e-28 97.5 14.7 1.2e-27 96.8 14.6 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194102.1_29622001_1 - 9.3e-06 25.1 16.9 1.3e-05 24.5 16.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Put_Phosphatase PF06888.10 001194769.1_29623001_1 - 4.3e-102 340.4 0.5 5e-102 340.1 0.5 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.5 001194769.1_29623001_1 - 6.3e-09 36.4 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.4 001194769.1_29623001_1 - 0.046 13.7 3.9 0.24 11.3 1.4 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.24 001194769.1_29623001_1 - 0.24 11.5 1.2 23 5.1 1.2 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sulfotransfer_1 PF00685.25 001194840.1_29623001_3 - 1.5e-84 283.5 0.1 1.8e-84 283.2 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001194840.1_29623001_3 - 2.3e-09 37.8 0.0 2.7e-06 27.8 0.1 2.2 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.25 001193512.1_29623001_3 - 5.8e-90 301.3 0.5 7e-90 301.0 0.5 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001193512.1_29623001_3 - 2.1e-06 28.2 0.0 0.00014 22.2 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family Sybindin PF04099.10 001194511.1_29622001_1 - 2e-44 150.9 0.0 2.4e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.11 001194511.1_29622001_1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region DUF4203 PF13886.4 001194308.1_29625001_3 - 1.3e-46 158.7 29.8 1.9e-46 158.1 29.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) BolA PF01722.16 001194470.2_29622001_2 - 9.1e-18 64.2 0.1 1.7e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 BolA-like protein HEAT_2 PF13646.4 001194645.2_29624001_3 - 1.5e-13 50.8 3.3 0.00017 21.8 0.2 4.0 2 1 0 3 3 3 3 HEAT repeats IFRD PF05004.11 001194645.2_29624001_3 - 0.012 14.6 0.5 1.2 8.1 0.2 2.5 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.6 001194645.2_29624001_3 - 0.022 14.5 4.8 1.2 8.8 1.1 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF3385) HEAT PF02985.20 001194645.2_29624001_3 - 0.45 10.8 3.6 64 4.1 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat CCDC92 PF14916.4 001194197.1_29623001_1 - 2.8e-24 84.5 9.3 4.5e-23 80.7 3.0 2.5 2 0 0 2 2 2 2 Coiled-coil domain of unknown function Exonuc_VII_L PF02601.13 001194197.1_29623001_1 - 0.096 12.1 8.1 0.15 11.5 8.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.10 001194197.1_29623001_1 - 0.15 11.3 17.8 0.23 10.7 17.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.4 001194197.1_29623001_1 - 0.33 10.1 7.6 0.55 9.4 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.6 001194197.1_29623001_1 - 0.58 7.5 14.2 0.77 7.1 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mei5 PF10376.7 001194197.1_29623001_1 - 0.66 9.7 14.8 0.99 9.1 14.0 1.7 1 1 0 1 1 1 0 Double-strand recombination repair protein NYD-SP28 PF14772.4 001194197.1_29623001_1 - 1.2 9.1 14.5 0.98 9.4 10.8 2.2 1 1 1 2 2 2 0 Sperm tail Fez1 PF06818.13 001194197.1_29623001_1 - 3 8.1 17.0 3.6 7.8 14.9 1.9 1 1 1 2 2 2 0 Fez1 IncA PF04156.12 001194197.1_29623001_1 - 3 7.4 24.8 6.7 6.3 17.0 2.8 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.7 001194197.1_29623001_1 - 3.6 6.5 19.3 12 4.7 19.3 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4618 PF15397.4 001194197.1_29623001_1 - 3.8 6.8 22.1 1.3 8.3 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Reo_sigmaC PF04582.10 001194197.1_29623001_1 - 3.8 6.7 7.6 7.2 5.8 5.8 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.10 001194197.1_29623001_1 - 4.3 7.3 24.1 2.3 8.2 0.2 3.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.4 001194197.1_29623001_1 - 5.4 6.9 15.6 1.5 8.7 5.1 3.2 1 1 1 3 3 3 0 FlxA-like protein 7tm_4 PF13853.4 001193788.1_29623001_1 - 2.3e-39 135.7 24.6 3e-39 135.3 24.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001193788.1_29623001_1 - 4.2e-21 75.2 27.5 1.4e-20 73.5 27.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001193788.1_29623001_1 - 9.8e-08 31.5 25.7 2.2e-07 30.4 25.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001194222.1_29623001_2 - 2.5e-47 161.8 8.6 3.1e-47 161.5 8.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194222.1_29623001_2 - 8.9e-27 93.8 13.2 1.6e-26 93.0 13.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001194222.1_29623001_2 - 0.00012 21.4 14.3 0.00023 20.5 14.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Sugar_tr PF00083.22 001194222.1_29623001_2 - 0.0075 15.0 6.2 0.1 11.3 0.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter 7TM_GPCR_Srbc PF10316.7 001194222.1_29623001_2 - 0.0098 15.3 6.5 0.02 14.3 6.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srsx PF10320.7 001194222.1_29623001_2 - 0.04 13.2 13.1 0.094 11.9 13.1 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Tetraspannin PF00335.18 001194290.1_29625001_2 - 5.2e-49 166.8 6.3 9.9e-49 165.9 6.3 1.4 1 0 0 1 1 1 1 Tetraspanin family Filament PF00038.19 001194266.1_29625001_1 - 2.7e-115 385.1 47.9 3.3e-115 384.8 47.9 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.12 001194266.1_29625001_1 - 9.2e-24 84.0 9.0 2.1e-23 82.8 9.0 1.7 1 0 0 1 1 1 1 Intermediate filament head (DNA binding) region Reo_sigmaC PF04582.10 001194266.1_29625001_1 - 0.00097 18.5 5.7 0.36 10.0 0.4 2.9 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Spc7 PF08317.9 001194266.1_29625001_1 - 0.0023 16.7 8.9 0.0023 16.7 8.9 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.7 001194266.1_29625001_1 - 0.037 14.1 39.5 0.61 10.2 8.6 3.8 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Trimer_CC PF08954.9 001194266.1_29625001_1 - 0.058 12.8 0.2 0.058 12.8 0.2 4.1 3 0 0 3 3 3 0 Trimerisation motif DUF1664 PF07889.10 001194266.1_29625001_1 - 0.14 12.0 19.4 0.14 12.0 2.5 4.0 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.7 001194266.1_29625001_1 - 0.23 10.7 37.0 0.26 10.6 9.1 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.10 001194266.1_29625001_1 - 0.23 11.3 17.3 0.48 10.3 0.5 4.0 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.4 001194266.1_29625001_1 - 0.55 9.4 31.2 0.82 8.8 13.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.4 001194266.1_29625001_1 - 0.73 9.0 41.2 0.028 13.7 11.1 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Patched PF02460.16 001194266.1_29625001_1 - 1.1 7.2 4.2 1.4 6.7 4.2 1.1 1 0 0 1 1 1 0 Patched family TPR_MLP1_2 PF07926.10 001194266.1_29625001_1 - 1.7 8.6 41.9 1.7 8.6 10.1 3.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.10 001194266.1_29625001_1 - 1.7 8.9 33.2 0.21 11.9 3.3 4.2 1 1 4 5 5 5 0 Centromere protein H (CENP-H) DUF3584 PF12128.6 001194266.1_29625001_1 - 2 5.7 39.1 4.7 4.4 38.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Prefoldin PF02996.15 001194266.1_29625001_1 - 2.4 8.0 25.6 0.043 13.6 1.9 5.1 4 1 0 4 4 4 0 Prefoldin subunit CENP-F_leu_zip PF10473.7 001194266.1_29625001_1 - 2.7 7.9 34.9 1 9.2 4.4 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5082 PF16888.3 001194266.1_29625001_1 - 2.7 8.2 26.8 4.9 7.4 4.1 4.5 3 2 0 3 3 3 0 Domain of unknown function (DUF5082) HMMR_N PF15905.3 001194266.1_29625001_1 - 3.1 7.1 37.3 0.26 10.6 5.9 3.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal IncA PF04156.12 001194266.1_29625001_1 - 3.2 7.4 44.7 2.9 7.5 7.9 3.7 1 1 3 4 4 4 0 IncA protein Lzipper-MIP1 PF14389.4 001194266.1_29625001_1 - 4.4 7.5 21.6 22 5.2 0.1 4.2 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF573 PF04504.12 001194266.1_29625001_1 - 4.4 7.9 8.8 7.2 7.2 0.4 3.7 2 2 2 4 4 4 0 Protein of unknown function, DUF573 HALZ PF02183.16 001194266.1_29625001_1 - 5.3 7.2 26.2 1.5 9.0 0.1 5.2 6 1 0 6 6 5 0 Homeobox associated leucine zipper Mnd1 PF03962.13 001194266.1_29625001_1 - 5.4 6.7 34.6 58 3.3 19.3 3.5 1 1 1 2 2 1 0 Mnd1 family APG6 PF04111.10 001194266.1_29625001_1 - 7 5.8 41.3 1.6e+04 -17.8 39.8 3.1 1 1 0 1 1 0 0 Autophagy protein Apg6 KASH_CCD PF14662.4 001194266.1_29625001_1 - 7.3 6.3 41.5 1 9.0 0.4 3.9 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH KLRAQ PF10205.7 001194266.1_29625001_1 - 9.2 6.5 27.0 2.5 8.3 11.0 3.8 2 2 0 3 3 3 0 Predicted coiled-coil domain-containing protein WD40_alt PF14077.4 001194266.1_29625001_1 - 9.3 6.1 11.3 44 3.9 1.0 4.3 5 0 0 5 5 3 0 Alternative WD40 repeat motif bZIP_1 PF00170.19 001194266.1_29625001_1 - 9.4 6.3 21.2 21 5.1 2.0 5.7 4 1 1 6 6 6 0 bZIP transcription factor Loricrin PF15847.3 001204365.1_29623001_1 - 1.3e-94 316.8 305.8 2.6e-49 167.9 206.2 2.1 1 1 1 2 2 2 2 Major keratinocyte cell envelope protein PTPLA PF04387.12 001193912.1_29623001_1 - 5.3e-59 198.5 10.9 9.1e-59 197.8 10.9 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF4578 PF15147.4 001194789.1_29622001_1 - 3.1e-61 205.6 0.8 4e-61 205.3 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4578) Kazal_1 PF00050.19 001193441.1_29621001_1 - 6.4e-14 51.6 6.1 1.1e-13 50.8 6.1 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 001193441.1_29621001_1 - 6.4e-07 29.3 5.3 6.4e-07 29.3 5.3 1.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain 7tm_4 PF13853.4 001193814.1_29622001_1 - 8.8e-47 160.0 23.8 1.1e-46 159.7 23.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001193814.1_29622001_1 - 5.2e-18 65.1 30.8 1.4e-17 63.7 30.8 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001193814.1_29622001_1 - 0.0063 15.8 20.2 0.0063 15.8 20.2 1.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Apelin PF15360.4 001190868.1_29621001_1 - 4.7e-30 103.8 7.4 5.6e-30 103.5 7.4 1.1 1 0 0 1 1 1 1 APJ endogenous ligand 7tm_4 PF13853.4 001193841.1_29622001_1 - 2.2e-40 139.0 22.8 2.6e-40 138.8 22.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001193841.1_29622001_1 - 1.8e-20 73.2 24.6 4e-20 72.0 24.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001193841.1_29622001_1 - 3.6e-06 26.4 21.1 6.7e-06 25.5 21.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Rad52_Rad22 PF04098.13 001194650.1_29623001_2 - 8.3e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.20 001194650.1_29623001_2 - 1.6e-05 24.5 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fer4_2 PF12797.5 001194849.1_29623001_3 - 8.1 6.6 9.1 7.5 6.8 0.5 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Ank_2 PF12796.5 001193702.1_29624001_1 - 2.4e-09 37.5 0.0 4.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001193702.1_29624001_1 - 1e-08 35.2 3.3 4.9e-05 23.5 0.2 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001193702.1_29624001_1 - 6e-08 32.2 0.6 0.0068 16.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.4 001193702.1_29624001_1 - 2.9e-07 30.8 0.3 0.017 15.6 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.28 001193702.1_29624001_1 - 0.00025 21.2 3.2 0.0029 17.9 0.3 3.2 3 0 0 3 3 3 1 Ankyrin repeat TMEM252 PF15664.3 001193966.1_29623001_3 - 1.2e-69 232.3 1.0 1.5e-68 228.7 0.0 2.1 1 1 1 2 2 2 1 Transmembrane protein 252 family DUF3040 PF11239.6 001193966.1_29623001_3 - 1.8 8.7 3.9 6 7.1 4.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) 7tm_4 PF13853.4 001194559.1_29623001_1 - 1.9e-109 365.6 22.4 2.5e-109 365.2 22.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194559.1_29623001_1 - 3.9e-19 68.8 20.2 9.3e-19 67.6 20.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194559.1_29623001_1 - 2.2e-09 37.0 12.9 2.2e-09 37.0 12.9 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4408 PF14364.4 001194559.1_29623001_1 - 0.31 10.7 5.0 0.37 10.4 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4408) ACT_3 PF10000.7 001193865.1_29624001_1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain UQ_con PF00179.24 001193865.1_29624001_3 - 2.3e-46 156.8 0.0 3.5e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001193865.1_29624001_3 - 0.0099 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001193865.1_29624001_3 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain Baculo_11_kDa PF06143.9 001193865.1_29624001_3 - 8 6.0 7.2 21 4.6 7.2 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF1356 PF07092.10 001194813.1_29624001_1 - 1.3e-80 269.9 6.9 3.3e-54 183.5 0.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1356) FGF-BP1 PF06473.10 001194149.1_29622001_2 - 3.9e-54 183.8 0.8 4.7e-54 183.5 0.8 1.0 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Folate_carrier PF01770.16 001194774.1_29624001_1 - 9.5e-159 528.4 23.9 1.3e-158 528.0 23.9 1.1 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.14 001194774.1_29624001_1 - 1e-12 47.5 17.4 1e-12 47.5 17.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Cadherin_C_2 PF16492.3 001194774.1_29624001_1 - 0.018 15.6 0.0 0.065 13.9 0.0 2.0 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Folate_carrier PF01770.16 001194774.1_29624001_3 - 1.4e-14 53.6 0.1 1.9e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 Reduced folate carrier Branch PF02485.19 001194134.1_29624001_1 - 2.6e-65 220.2 0.3 3.4e-65 219.8 0.3 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme 7tm_4 PF13853.4 001194096.1_29622001_1 - 3.7e-48 164.5 12.3 5.5e-48 164.0 12.3 1.2 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194096.1_29622001_1 - 6.7e-22 77.9 13.1 1.7e-21 76.5 13.1 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SLC3A2_N PF16028.3 001194096.1_29622001_1 - 3.8 7.0 5.3 0.82 9.1 1.0 2.0 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus LRR_8 PF13855.4 001193828.2_29624001_2 - 7e-09 35.2 22.1 1.1e-05 25.0 3.7 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 001193828.2_29624001_2 - 2.2e-08 34.1 7.5 6.7e-05 23.0 1.0 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001193828.2_29624001_2 - 2.5e-06 27.0 0.0 3.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.31 001193828.2_29624001_2 - 0.027 14.7 1.2 42 5.1 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat p450 PF00067.20 001194560.1_29624001_2 - 1.2e-135 452.7 0.0 1.5e-135 452.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HEAT_2 PF13646.4 001194574.1_29629001_2 - 3.3e-18 65.7 1.6 1.8e-08 34.5 0.0 6.0 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.20 001194574.1_29629001_2 - 2.4e-16 58.3 12.4 0.00027 20.8 0.0 8.2 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.4 001194574.1_29629001_2 - 5.2e-14 52.2 4.3 1.7e-06 28.2 0.0 6.8 8 0 0 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.5 001194574.1_29629001_2 - 1.1e-08 35.4 8.9 0.00048 20.5 0.0 7.4 7 2 2 9 9 9 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.5 001194574.1_29629001_2 - 1.7e-08 34.5 3.5 9.4e-05 22.3 0.3 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.11 001194574.1_29629001_2 - 2e-06 27.0 2.4 1.2 8.1 0.1 5.5 4 2 2 6 6 6 3 Interferon-related developmental regulator (IFRD) RIX1 PF08167.10 001194574.1_29629001_2 - 2.2e-05 24.2 0.6 0.084 12.5 0.0 4.9 4 3 1 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.21 001194574.1_29629001_2 - 3.9e-05 23.4 1.0 10 6.2 0.0 6.2 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.7 001194574.1_29629001_2 - 0.0098 15.9 0.1 0.37 10.8 0.0 3.5 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 7tm_4 PF13853.4 001194547.1_29623001_3 - 3.9e-139 463.0 25.6 4.6e-139 462.7 25.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194547.1_29623001_3 - 4.2e-18 65.4 23.0 8.4e-18 64.4 23.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194547.1_29623001_3 - 1.1e-05 24.8 23.6 4.9e-05 22.7 23.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx MARVEL PF01284.21 001194830.2_29622001_2 - 3.4e-24 85.4 14.2 4.3e-24 85.0 14.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain Phage_holin_3_6 PF07332.9 001194830.2_29622001_2 - 1.9 8.4 8.8 29 4.6 8.8 2.2 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MEA1 PF06910.9 001194869.1_29624001_3 - 7.2e-115 380.5 8.7 9.4e-115 380.1 8.7 1.1 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) Asparaginase_2 PF01112.16 001194716.2_29625001_1 - 7.1e-106 353.5 7.5 1e-105 353.1 7.5 1.1 1 0 0 1 1 1 1 Asparaginase RIIa PF02197.15 001193872.1_29623001_2 - 0.027 14.0 0.1 0.068 12.7 0.1 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Phospholamban PF04272.12 001190894.1_29622001_1 - 9.3e-35 117.8 10.4 1.6e-34 117.0 10.4 1.4 1 0 0 1 1 1 1 Phospholamban Sarcolipin PF05366.9 001190894.1_29622001_1 - 0.2 11.2 4.8 0.43 10.2 4.8 1.5 1 0 0 1 1 1 0 Sarcolipin IQ PF00612.25 001277943.1_29622001_3 - 4.7e-08 32.0 26.3 1.5e-05 24.2 0.8 4.5 4 1 0 4 4 4 3 IQ calmodulin-binding motif 7tm_4 PF13853.4 001194213.1_29623001_1 - 7.2e-81 271.8 10.4 8.9e-81 271.5 10.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194213.1_29623001_1 - 4.8e-07 29.1 4.5 1e-06 28.0 4.4 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194213.1_29623001_1 - 0.0005 19.4 1.7 0.00077 18.8 1.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UPF0449 PF15136.4 001194023.1_29621001_1 - 6.4e-34 116.3 0.2 7.4e-34 116.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 KfrA_N PF11740.6 001194023.1_29621001_1 - 0.18 12.4 6.7 0.37 11.4 6.5 1.6 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term NUDIX PF00293.26 001194362.1_29623001_1 - 6.8e-05 22.8 0.2 0.17 11.8 0.0 3.1 3 0 0 3 3 3 2 NUDIX domain UPF0193 PF05250.9 001193895.1_29623001_1 - 1.8e-87 292.5 8.3 1.8e-87 292.5 8.3 1.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) Complex1_LYR PF05347.13 001193351.1_29621001_1 - 1.4e-15 56.9 0.4 1.7e-15 56.7 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.4 001193351.1_29621001_1 - 0.00015 22.3 0.6 0.00017 22.1 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.4 001193351.1_29621001_1 - 0.0033 17.8 0.0 0.0036 17.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF1320 PF07030.10 001193351.1_29621001_1 - 0.039 14.0 0.9 2.6 8.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1320) S1-like PF14444.4 001194153.1_29622001_3 - 2e-20 72.5 5.2 1.1e-08 34.8 1.3 3.2 3 0 0 3 3 3 3 S1-like Calc_CGRP_IAPP PF00214.17 001194708.1_29622001_2 - 6.7e-07 29.6 0.7 8.1e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Calcitonin / CGRP / IAPP family HTH_21 PF13276.4 001194708.1_29622001_2 - 0.17 11.9 0.2 0.28 11.2 0.2 1.3 1 0 0 1 1 1 0 HTH-like domain Gly_acyl_tr_N PF06021.9 001257270.1_29622001_1 - 3.5e-89 298.1 0.9 4.6e-89 297.7 0.9 1.1 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Gly_acyl_tr_C PF08444.8 001257270.1_29622001_1 - 7.5e-46 154.2 0.6 1.9e-45 152.9 0.6 1.7 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region RE_TdeIII PF09520.8 001257270.1_29622001_1 - 0.073 12.6 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII FR47 PF08445.8 001257270.1_29622001_1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein 7tm_4 PF13853.4 001194206.1_29623001_1 - 5e-54 183.8 18.6 6.2e-54 183.5 18.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194206.1_29623001_1 - 8.7e-28 97.2 22.8 1.7e-27 96.2 22.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001194206.1_29623001_1 - 1.9e-05 24.1 17.7 3.6e-05 23.1 17.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4677 PF15726.3 001194183.1_29625001_3 - 7.8e-114 378.5 6.5 1.3e-113 377.8 6.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4677) Reo_sigmaC PF04582.10 001194183.1_29625001_3 - 0.052 12.8 0.0 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Histone_H2A_C PF16211.3 001194037.1_29621001_1 - 1.6e-20 72.4 2.4 2.6e-20 71.7 2.4 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.22 001194037.1_29621001_1 - 1.4e-16 61.0 0.0 1.8e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001194037.1_29621001_1 - 4.2e-05 23.6 0.0 5.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone p450 PF00067.20 001193838.1_29625001_2 - 3.6e-121 405.0 0.0 4.3e-121 404.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alpha_L_fucos PF01120.15 001193838.1_29625001_2 - 0.043 13.1 0.2 0.065 12.6 0.2 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase Nuc_deoxyrib_tr PF05014.13 001193983.1_29622001_2 - 1.9e-15 56.9 0.0 2.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase p450 PF00067.20 001194627.1_29625001_3 - 5.6e-103 345.0 0.0 6.4e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH PF00642.22 001198701.1_29623001_3 - 2.5e-09 36.7 2.7 7.9e-09 35.1 2.7 2.0 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.4 001198701.1_29623001_3 - 5.7e-08 32.4 8.6 1.2e-07 31.4 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001198701.1_29623001_3 - 6.8e-07 28.9 11.1 1.5e-06 27.8 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001198701.1_29623001_3 - 1.5e-05 25.0 11.1 3e-05 24.0 11.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.4 001198701.1_29623001_3 - 8.2e-05 22.4 10.1 0.0002 21.2 10.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001198701.1_29623001_3 - 0.00012 21.9 13.1 0.00024 20.8 13.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.3 001198701.1_29623001_3 - 0.00014 21.8 5.7 0.00042 20.3 5.7 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.23 001198701.1_29623001_3 - 0.0002 21.0 11.2 0.00042 20.0 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.4 001198701.1_29623001_3 - 0.0079 16.2 9.9 0.022 14.8 9.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.6 001198701.1_29623001_3 - 0.0092 15.7 5.1 0.02 14.6 5.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.4 001198701.1_29623001_3 - 0.017 14.8 8.1 0.034 13.9 8.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.4 001198701.1_29623001_3 - 0.042 14.2 2.5 0.15 12.4 2.5 2.1 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-P11 PF03854.12 001198701.1_29623001_3 - 0.49 10.0 5.4 0.98 9.0 5.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger 7tm_4 PF13853.4 001193494.1_29622001_1 - 1.4e-47 162.7 21.2 1.7e-47 162.4 21.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001193494.1_29622001_1 - 2.2e-21 76.1 21.3 3.5e-21 75.5 21.3 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DuoxA PF10204.7 001194505.1_29622001_1 - 7.8e-114 379.2 4.2 8.9e-114 379.0 4.2 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Neurensin PF14927.4 001194505.1_29622001_1 - 0.037 13.6 2.2 1.9 8.0 0.0 2.9 3 0 0 3 3 3 0 Neurensin DUF4516 PF14990.4 001194505.1_29622001_1 - 0.06 12.9 1.4 8.5 6.1 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) DUF2530 PF10745.7 001194505.1_29622001_1 - 0.075 13.1 0.3 0.075 13.1 0.3 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) TMEM40 PF15817.3 001194505.1_29622001_1 - 0.12 12.0 2.9 0.3 10.7 0.1 2.4 2 1 1 3 3 3 0 Transmembrane protein 40 family Acetyltransf_1 PF00583.23 001194477.1_29622001_2 - 1.4e-19 70.3 0.1 2e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.5 001194477.1_29622001_2 - 1.7e-09 37.8 0.1 2.9e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.5 001194477.1_29622001_2 - 5.2e-06 26.3 0.0 8.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.8 001194477.1_29622001_2 - 3.7e-05 23.5 0.0 6.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.4 001194477.1_29622001_2 - 9.6e-05 22.3 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.3 001194477.1_29622001_2 - 0.054 12.8 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_6 PF13480.5 001194477.1_29622001_2 - 0.079 13.0 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.5 001194477.1_29622001_2 - 0.11 12.6 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Thymidylate_kin PF02223.15 001194775.1_29622001_1 - 2.2e-41 141.4 0.2 9.4e-33 113.3 0.0 2.0 1 1 1 2 2 2 2 Thymidylate kinase AAA_33 PF13671.4 001194775.1_29622001_1 - 0.0056 16.7 0.0 0.01 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain CPT PF07931.10 001194775.1_29622001_1 - 0.048 13.4 0.1 0.35 10.6 0.0 2.3 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ADK PF00406.20 001194775.1_29622001_1 - 0.066 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase DUF3347 PF11827.6 001194775.1_29622001_1 - 0.08 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) KTI12 PF08433.8 001194775.1_29622001_1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CRAL_TRIO PF00650.18 001194395.1_29624001_3 - 5.3e-34 117.1 0.0 8.9e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.4 001194395.1_29624001_3 - 9.2e-08 32.2 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.13 001194395.1_29624001_3 - 3.4e-06 27.0 0.0 7.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain 7tm_4 PF13853.4 001194490.1_29623001_2 - 5.9e-47 160.6 22.6 7.7e-47 160.2 22.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001194490.1_29623001_2 - 8.7e-23 80.8 25.1 2.5e-22 79.3 25.1 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Arf PF00025.19 001194058.2_29628001_1 - 1.1e-76 256.0 0.0 1.5e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.11 001194058.2_29628001_1 - 1.7e-13 50.7 0.0 2.4e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 001194058.2_29628001_1 - 1.1e-12 47.7 0.0 1.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.8 001194058.2_29628001_1 - 1.4e-11 44.1 0.0 2.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.18 001194058.2_29628001_1 - 3.5e-10 39.4 0.5 1.1e-06 28.0 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.10 001194058.2_29628001_1 - 7e-09 35.2 0.0 9.9e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001194058.2_29628001_1 - 0.0039 17.1 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 001194058.2_29628001_1 - 0.09 11.9 0.2 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SpoOE-like PF09388.8 001194058.2_29628001_1 - 0.21 11.4 1.2 0.46 10.3 1.2 1.5 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein DUF2754 PF10953.6 001194058.2_29628001_1 - 0.42 10.7 2.3 15 5.8 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2754) Aldo_ket_red PF00248.19 001195575.2_29627001_1 - 1.8e-55 188.0 0.0 2.3e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF846 PF05832.10 134905.1_26224120_1 - 4.1e-31 107.8 2.2 5.7e-31 107.3 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) RNA_pol_Rpc4 PF05132.12 134905.1_26224120_1 - 0.7 10.2 7.5 1.2 9.4 7.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Peptidase_M14 PF00246.22 012533.2_45723001_3 - 1.1e-97 327.2 0.0 1.4e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.14 012533.2_45723001_3 - 2.3e-18 66.2 1.5 4.8e-18 65.2 1.1 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Intimin_C PF07979.9 012533.2_45723001_3 - 0.0037 17.5 0.1 0.0085 16.4 0.1 1.5 1 0 0 1 1 1 1 Intimin C-type lectin domain DUF3819 PF12842.5 012533.2_45723001_3 - 0.17 11.7 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) GAGE PF05831.9 001322461.1_39721001_1 - 6.4e-42 142.3 11.4 7.4e-42 142.1 11.4 1.0 1 0 0 1 1 1 1 GAGE protein PIP5K PF01504.16 027712.1_26229120_1 - 9.5e-88 293.8 0.0 1.2e-87 293.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.22 001114166.2_39727001_2 - 7.3e-28 97.4 15.9 1.2e-27 96.7 15.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.19 001114166.2_39727001_2 - 5.6e-13 49.2 2.6 5.6e-13 49.2 2.6 2.2 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif TNF PF00229.16 001242728.1_37622001_1 - 4.8e-23 81.3 0.0 5.9e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family AKAP2_C PF15304.4 001204205.1_37626001_1 - 7.5e-10 38.5 20.6 7.5e-10 38.5 20.6 3.8 2 2 0 2 2 2 1 A-kinase anchor protein 2 C-terminus Collagen PF01391.16 001242748.1_37624001_1 - 1.5e-07 30.9 28.2 1.5e-07 30.9 28.2 5.8 6 0 0 6 6 6 1 Collagen triple helix repeat (20 copies) Maelstrom PF13017.4 001291856.1_37624001_1 - 1.3e-53 181.8 0.3 1.9e-53 181.2 0.3 1.2 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.8 001291856.1_37624001_1 - 3.1e-20 72.4 0.0 6.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.17 001291856.1_37624001_1 - 0.00043 20.5 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box DnaJ PF00226.29 001205038.1_37623001_1 - 2.5e-19 69.0 0.0 7.6e-19 67.5 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain zf-H2C2_2 PF13465.4 001123357.1_37628001_1 - 3.1e-47 156.8 98.2 1.6e-08 34.5 0.7 12.1 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2 PF00096.24 001123357.1_37628001_1 - 3.8e-31 105.6 102.1 0.00015 21.9 1.1 11.6 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001123357.1_37628001_1 - 1.8e-21 74.8 103.8 0.0087 16.7 2.7 11.9 12 0 0 12 12 12 10 C2H2-type zinc finger zf-H2C2_5 PF13909.4 001123357.1_37628001_1 - 4e-16 58.3 81.0 1.8e-06 27.5 0.6 10.4 10 0 0 10 10 10 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.6 001123357.1_37628001_1 - 5.3e-07 29.7 58.6 0.039 14.1 0.2 11.2 9 1 2 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001123357.1_37628001_1 - 0.012 15.8 2.5 0.012 15.8 2.5 9.8 11 0 0 11 11 11 0 Zinc-finger of C2H2 type Insulin PF00049.16 001242705.1_37623001_1 - 2.1e-12 47.7 6.0 1.5e-09 38.6 6.0 2.5 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family IGF2_C PF08365.9 001242705.1_37623001_1 - 1.2e-08 34.7 2.2 2.4e-08 33.7 2.2 1.6 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Ins_beta PF03488.12 001242705.1_37623001_1 - 2 8.3 4.7 19 5.2 4.7 2.2 1 1 0 1 1 1 0 Nematode insulin-related peptide beta type MHC_I PF00129.16 001242749.1_37623001_1 - 1.3e-49 168.0 0.0 1.8e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001242749.1_37623001_1 - 8.8e-13 48.4 0.0 2.4e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001242749.1_37623001_1 - 1.3e-05 25.5 0.0 4.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.4 001242749.1_37623001_1 - 6.5e-05 23.1 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001242749.1_37623001_1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001242749.1_37623001_1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain dsrm PF00035.24 001242749.1_37623001_1 - 0.13 12.9 0.0 4.5 7.9 0.0 2.7 3 0 0 3 3 3 0 Double-stranded RNA binding motif Cass2 PF14526.4 001242749.1_37623001_1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Integron-associated effector binding protein MHC_II_alpha PF00993.18 001242716.1_37622001_1 - 1.8e-34 117.2 0.1 2.4e-34 116.7 0.1 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001242716.1_37622001_1 - 1.2e-27 94.9 0.4 1.2e-27 94.9 0.4 1.6 2 0 0 2 2 2 1 C1-set C-terminal domain C1-set PF07654.13 001242716.1_37622001_1 - 6.4e-23 80.9 0.1 1.4e-22 79.8 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001242716.1_37622001_1 - 0.0002 21.8 0.0 0.00032 21.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.13 001242716.1_37622001_1 - 0.0022 17.7 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Marek's disease glycoprotein A C2-set_2 PF08205.10 001242716.1_37622001_1 - 0.0048 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 001242716.1_37622001_1 - 0.04 14.1 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Neur_chan_LBD PF02931.21 001168262.1_37624001_1 - 2.7e-50 170.7 0.0 5.4e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001168262.1_37624001_1 - 1e-48 166.4 0.0 1.3e-48 166.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.7 001168262.1_37624001_1 - 1.5 6.9 4.9 2.1 6.4 4.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Proteasome PF00227.24 001242744.1_37622001_1 - 1.9e-46 157.8 0.1 2.3e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit YedD PF13987.4 001242744.1_37622001_1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 YedD-like protein FHA PF00498.24 001242725.1_37623001_1 - 1.7e-13 50.6 0.0 2.5e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain PHD PF00628.27 001242725.1_37623001_1 - 4e-06 26.5 10.4 6.7e-06 25.8 10.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.4 001242725.1_37623001_1 - 0.044 13.2 7.7 0.082 12.3 7.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.4 001242725.1_37623001_1 - 0.37 10.6 6.8 0.79 9.5 6.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001242725.1_37623001_1 - 0.58 10.0 6.2 2.3 8.1 6.2 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.4 001242725.1_37623001_1 - 0.78 9.5 6.0 1.7 8.4 6.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.4 001242725.1_37623001_1 - 1.6 8.4 7.9 3 7.5 7.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.4 001242725.1_37623001_1 - 2.2 8.5 10.3 4.1 7.6 10.3 1.5 1 0 0 1 1 1 0 Ring finger domain INO80_Ies4 PF08193.9 001242725.1_37623001_1 - 3.9 7.3 9.3 5.3 6.8 9.3 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 MHC_I PF00129.16 001242715.1_37623001_1 - 4.8e-64 215.1 3.1 7e-64 214.5 3.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001242715.1_37623001_1 - 2.6e-14 53.3 0.0 7.4e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001242715.1_37623001_1 - 8.8e-07 29.3 0.2 2.7e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.4 001242715.1_37623001_1 - 6.7e-05 23.0 0.1 0.00046 20.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001242715.1_37623001_1 - 0.00086 19.3 0.2 0.0056 16.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain MHC_I_3 PF16497.3 001242715.1_37623001_1 - 0.0064 15.9 0.3 0.0092 15.3 0.3 1.1 1 0 0 1 1 1 1 MHC-I family domain C2-set_2 PF08205.10 001242715.1_37623001_1 - 0.0098 15.8 0.5 0.071 13.1 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Guanylate_kin PF00625.19 001246852.1_37623001_1 - 1.2e-47 161.9 0.2 2.2e-47 160.9 0.2 1.5 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.6 001246852.1_37623001_1 - 3.1e-22 78.3 6.1 9.1e-22 76.8 6.1 1.9 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.26 001246852.1_37623001_1 - 0.0012 18.2 0.0 0.0047 16.4 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.4 001246852.1_37623001_1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.15 001246852.1_37623001_1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain 7tm_1 PF00001.19 001123358.1_37625001_3 - 2.1e-40 138.5 4.7 3.2e-40 138.0 4.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cytochrom_B_N_2 PF13631.4 001123358.1_37625001_3 - 0.032 14.1 0.1 0.091 12.6 0.1 1.7 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF781 PF05612.10 001323776.1_37623001_1 - 2.2e-68 230.7 0.1 2.8e-68 230.4 0.1 1.0 1 0 0 1 1 1 1 Mouse protein of unknown function (DUF781) Septin PF00735.16 136592.1_26225120_3 - 3e-34 118.4 0.0 1.9e-33 115.8 0.0 1.8 1 1 0 1 1 1 1 Septin Na_H_Exchanger PF00999.19 136666.1_26228120_2 - 5.7e-26 91.1 6.9 1.3e-25 89.9 6.9 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family PIG-H PF10181.7 136666.1_26228120_2 - 0.21 11.4 0.4 0.34 10.7 0.4 1.3 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component Na_H_Exchanger PF00999.19 136666.1_26228120_3 - 8.8e-39 133.2 14.4 1.2e-38 132.8 14.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.3 136666.1_26228120_3 - 0.0089 16.1 0.3 0.017 15.2 0.3 1.3 1 0 0 1 1 1 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Glyco_transf_29 PF00777.16 001323777.1_37623001_1 - 8.9e-74 248.1 0.0 1.1e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF1443 PF07280.9 001323777.1_37623001_1 - 0.004 16.8 1.0 0.0083 15.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1443) ERM PF00769.17 001284108.1_29525001_3 - 2e-75 253.7 52.4 2e-75 253.7 52.4 2.4 2 1 1 3 3 3 1 Ezrin/radixin/moesin family FERM_M PF00373.16 001284108.1_29525001_3 - 9.6e-29 100.0 1.2 9.6e-29 100.0 1.2 3.4 2 1 1 3 3 3 1 FERM central domain FERM_C PF09380.8 001284108.1_29525001_3 - 6.7e-28 96.8 0.0 1.9e-27 95.3 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.8 001284108.1_29525001_3 - 1.5e-14 53.5 1.1 4.4e-14 52.0 0.2 2.3 2 0 0 2 2 2 1 FERM N-terminal domain Aldo_ket_red PF00248.19 001283596.1_29523001_1 - 1.1e-56 192.1 0.0 1.3e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Filament PF00038.19 001284985.1_29525001_2 - 1.4e-07 31.3 16.6 0.00023 20.7 0.0 2.3 2 0 0 2 2 2 2 Intermediate filament protein Spc7 PF08317.9 001284985.1_29525001_2 - 0.00062 18.6 10.8 0.00062 18.6 10.8 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein LemA PF04011.10 001284985.1_29525001_2 - 0.0024 17.2 0.9 0.0047 16.3 0.7 1.6 1 1 0 1 1 1 1 LemA family DUF4407 PF14362.4 001284985.1_29525001_2 - 0.22 10.7 3.4 0.39 9.9 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.4 001284985.1_29525001_2 - 0.22 11.5 5.5 0.6 10.1 5.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DIT1_PvcA PF05141.10 001284985.1_29525001_2 - 0.55 9.5 4.0 0.9 8.8 4.0 1.4 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Bap31 PF05529.10 001284985.1_29525001_2 - 2.4 7.6 9.6 0.74 9.3 5.9 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like JAB PF01398.19 001287664.1_29524001_3 - 3.8e-32 110.6 0.0 6.8e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.4 001287664.1_29524001_3 - 2.8e-15 56.6 1.3 4.8e-15 55.8 1.3 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.4 001287664.1_29524001_3 - 5.6e-06 26.0 0.0 9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Phage_int_SAM_5 PF13102.4 001287664.1_29524001_3 - 0.012 15.7 2.7 0.02 15.0 2.7 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF4525 PF15027.4 001287664.1_29524001_3 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) LRR_4 PF12799.5 001284995.1_29524001_1 - 7.8e-38 127.6 43.9 1.4e-08 34.7 1.6 7.1 2 2 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001284995.1_29524001_1 - 6.2e-30 103.8 48.1 6.3e-11 41.9 0.3 4.1 1 1 4 5 5 5 5 Leucine-rich repeat LRR_8 PF13855.4 001284995.1_29524001_1 - 5.5e-22 77.2 41.9 5.2e-07 29.2 9.0 6.2 1 1 2 5 5 5 5 Leucine rich repeat UB2H PF14814.4 001284995.1_29524001_1 - 0.53 10.2 5.5 76 3.3 0.0 4.6 2 1 3 6 6 6 0 Bifunctional transglycosylase second domain LRR_6 PF13516.4 001284995.1_29524001_1 - 1.1 9.3 31.8 12 6.1 0.2 8.7 11 0 0 11 11 11 0 Leucine Rich repeat LRR_1 PF00560.31 001284995.1_29524001_1 - 2.1 9.0 33.8 1 10.0 0.1 9.6 9 2 1 10 10 10 0 Leucine Rich Repeat DUF1773 PF08593.8 001284995.1_29524001_1 - 8.3 7.4 14.6 54 4.8 0.0 5.8 6 1 1 7 7 7 0 Domain of unknown function V-set PF07686.15 001284136.1_29522001_3 - 4.4e-15 55.7 0.0 7.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001284136.1_29522001_3 - 2.1e-06 28.1 0.0 4.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001284136.1_29522001_3 - 3.1e-06 27.1 0.0 8.8e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001284136.1_29522001_3 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.4 001284136.1_29522001_3 - 0.01 16.0 0.1 0.035 14.3 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin domain RskA PF10099.7 001284136.1_29522001_3 - 0.014 15.5 1.7 0.035 14.3 1.7 1.7 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DEAD PF00270.27 001287668.1_29524001_2 - 2.4e-29 102.2 0.0 3.9e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001287668.1_29524001_2 - 1e-26 93.3 0.0 3.1e-26 91.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AP3D1 PF06375.9 001285003.1_29523001_1 - 2.9 8.0 20.5 2.2 8.4 16.1 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 OAD_gamma PF04277.11 001285003.1_29523001_1 - 8.5 6.9 8.6 14 6.2 8.6 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Mito_carr PF00153.25 001285005.1_29525001_2 - 5.7e-15 54.9 0.1 3.3e-09 36.4 0.0 3.2 3 0 0 3 3 3 2 Mitochondrial carrier protein ECH_1 PF00378.18 001285012.1_29523001_2 - 6.2e-37 127.1 0.0 9e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.17 001285012.1_29523001_2 - 1e-28 99.3 0.1 2.2e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein ECH_2 PF16113.3 001285012.1_29523001_2 - 3e-17 63.0 0.0 4.1e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PCI PF01399.25 001284151.1_29523001_1 - 0.00092 19.6 0.1 0.51 10.7 0.0 2.9 1 1 1 2 2 2 2 PCI domain BORG_CEP PF14957.4 001285016.1_29525001_1 - 1.1e-21 78.0 0.2 1.1e-21 78.0 0.2 2.4 3 0 0 3 3 3 1 Cdc42 effector PBD PF00786.26 001285016.1_29525001_1 - 2.7e-12 46.8 0.0 5.8e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain GST_N_3 PF13417.4 001287693.1_29522001_2 - 4.2e-19 68.6 0.0 9.4e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001287693.1_29522001_2 - 3.1e-15 56.1 0.0 6e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001287693.1_29522001_2 - 3.9e-14 52.6 0.0 8.8e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001287693.1_29522001_2 - 1.3e-09 38.0 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001287693.1_29522001_2 - 1.7e-07 30.9 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001287693.1_29522001_2 - 3.3e-07 30.3 0.1 5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 001287693.1_29522001_2 - 0.0093 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.3 001287693.1_29522001_2 - 0.014 15.8 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FGF PF00167.16 001284156.1_29524001_1 - 4.4e-42 143.0 0.2 7e-42 142.3 0.2 1.3 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 001284156.1_29524001_1 - 0.013 15.6 0.0 0.045 13.8 0.0 1.9 2 0 0 2 2 2 0 Fascin domain SKG6 PF08693.8 001284156.1_29524001_1 - 4.8 6.5 5.9 1.1 8.6 0.7 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ADH_zinc_N PF00107.24 001284167.1_29525001_1 - 4.2e-20 71.8 0.1 8.1e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.4 001284167.1_29525001_1 - 6.7e-20 72.3 0.0 1.4e-19 71.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001284167.1_29525001_1 - 2.3e-09 37.0 0.0 5.2e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SLX9 PF15341.4 001284169.1_29524001_2 - 1.7e-23 83.3 7.9 2.4e-23 82.8 7.9 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Tau95 PF09734.7 001283665.1_29526001_2 - 1.3e-80 271.2 0.0 1.9e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit LAT PF15234.4 001283665.1_29526001_2 - 0.41 10.3 3.1 0.75 9.4 3.1 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells tRNA-synt_1c PF00749.19 001284174.1_29525001_1 - 1.8e-114 381.8 0.0 2.5e-114 381.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.13 001284174.1_29525001_1 - 8.7e-50 168.7 0.0 2.1e-49 167.5 0.0 1.6 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.16 001284174.1_29525001_1 - 3.8e-43 147.2 0.0 6.8e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.13 001284174.1_29525001_1 - 2.6e-28 98.6 2.1 4.9e-28 97.7 2.1 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF5136 PF17199.2 001284174.1_29525001_1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) 7tm_1 PF00001.19 001287717.1_29523001_3 - 2e-55 187.8 10.0 2.8e-55 187.3 10.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001287717.1_29523001_3 - 8.7e-09 35.0 11.7 3.5e-06 26.5 5.9 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001287717.1_29523001_3 - 4.2e-05 23.3 4.4 0.00049 19.8 3.2 2.2 2 0 0 2 2 2 1 Olfactory receptor Proteasome PF00227.24 001283167.1_29522001_3 - 5.8e-42 143.2 0.1 6.7e-42 143.0 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit E1_DerP2_DerF2 PF02221.13 001287733.1_29521001_1 - 1.6e-15 57.6 0.2 1.9e-15 57.4 0.2 1.1 1 0 0 1 1 1 1 ML domain GST_C_3 PF14497.4 001289964.1_29522001_2 - 2.9e-16 59.3 0.0 5.6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001289964.1_29522001_2 - 2.2e-14 53.3 0.0 3.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001289964.1_29522001_2 - 0.00013 22.1 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001289964.1_29522001_2 - 0.0026 17.5 0.0 0.0069 16.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LCM PF04072.12 001283175.1_29523001_2 - 7.5e-41 140.0 0.0 1.8e-40 138.8 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Hormone_1 PF00103.18 001290287.1_29522001_1 - 4.4e-35 121.3 0.1 6e-35 120.8 0.1 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Hormone_1 PF00103.18 001290287.1_29522001_3 - 2.6e-08 33.8 0.3 3.3e-08 33.4 0.3 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Asp_protease_2 PF13650.4 001291294.1_29529001_1 - 0.00078 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001291294.1_29529001_1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001291294.1_29529001_1 - 0.052 14.0 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001291294.1_29529001_2 - 5e-15 55.2 0.0 9.3e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001291294.1_29529001_2 - 7.4e-15 54.9 1.8 1.9e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001291294.1_29529001_2 - 0.00044 20.2 0.1 0.00088 19.3 0.1 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001291294.1_29529001_2 - 0.0012 18.6 4.5 0.002 17.9 4.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001291294.1_29529001_2 - 0.0027 17.3 0.2 0.0064 16.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001291294.1_29529001_2 - 0.0039 16.9 0.4 0.0066 16.2 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 SlyX PF04102.10 001291294.1_29529001_2 - 0.23 12.0 2.1 0.56 10.7 2.1 1.7 1 0 0 1 1 1 0 SlyX CCDC106 PF15794.3 001291294.1_29529001_2 - 0.31 10.6 2.9 0.43 10.1 1.8 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001291294.1_29529001_2 - 0.32 11.3 3.9 0.65 10.3 3.9 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.3 001291294.1_29529001_2 - 0.33 10.9 3.0 0.63 10.0 3.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF972 PF06156.11 001291294.1_29529001_2 - 0.36 11.3 2.7 0.95 10.0 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.19 001291294.1_29529001_2 - 0.45 10.5 5.2 1.3 9.0 5.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor ZapB PF06005.10 001291294.1_29529001_2 - 0.69 10.3 9.1 1.6 9.1 9.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapB IncA PF04156.12 001291294.1_29529001_2 - 0.78 9.4 3.1 1.6 8.4 3.1 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.13 001291294.1_29529001_2 - 1.3 8.7 5.1 3.2 7.5 5.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Orn_Arg_deC_N PF02784.14 001292053.1_29527001_3 - 3.6e-64 216.4 0.2 4.6e-64 216.1 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001292053.1_29527001_3 - 1.9e-24 85.8 0.0 3.4e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain RCC1 PF00415.16 001293645.1_29529001_1 - 5e-35 119.8 10.2 5.2e-11 42.9 1.5 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.29 001293645.1_29529001_1 - 4.8e-33 113.6 10.1 7.9e-17 61.3 1.3 3.4 2 1 1 3 3 3 2 BTB/POZ domain Ank_5 PF13857.4 001293645.1_29529001_1 - 2.7e-10 40.2 0.0 0.00066 19.8 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001293645.1_29529001_1 - 8.1e-10 39.0 0.0 3.4e-09 37.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.4 001293645.1_29529001_1 - 6.5e-09 35.2 9.6 0.0025 17.4 0.1 5.8 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.4 001293645.1_29529001_1 - 7.8e-09 35.8 0.0 6.1e-06 26.6 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.28 001293645.1_29529001_1 - 1.1e-06 28.7 0.0 0.02 15.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.4 001293645.1_29529001_1 - 4.3e-06 26.5 0.0 0.027 14.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF3342 PF11822.6 001293645.1_29529001_1 - 0.19 11.8 1.7 0.35 11.0 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) Orn_Arg_deC_N PF02784.14 001301783.1_29527001_2 - 3.9e-64 216.3 0.2 5e-64 216.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301783.1_29527001_2 - 2e-24 85.7 0.0 3.6e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-H2C2_2 PF13465.4 001302759.1_29522001_1 - 7.8e-14 51.3 25.0 6.4e-10 38.9 0.3 4.9 4 1 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.24 001302759.1_29522001_1 - 1.7e-13 50.0 30.8 0.00029 21.0 0.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001302759.1_29522001_1 - 7.3e-10 38.7 29.1 0.0032 18.0 1.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger FYVE PF01363.19 001302759.1_29522001_1 - 0.00029 20.8 18.7 0.0071 16.3 3.4 2.6 1 1 1 2 2 2 2 FYVE zinc finger zf-C2H2_jaz PF12171.6 001302759.1_29522001_1 - 0.032 14.4 9.2 4.8 7.5 1.5 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001302759.1_29522001_1 - 0.04 13.6 0.8 0.04 13.6 0.8 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.5 001302759.1_29522001_1 - 0.075 13.3 0.4 0.075 13.3 0.4 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.4 001302759.1_29522001_1 - 0.087 12.5 1.1 0.087 12.5 1.1 4.9 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.3 001302759.1_29522001_1 - 0.43 11.2 7.0 2.9 8.6 4.2 2.5 1 1 2 3 3 3 0 zinc-ribbon family zf-C2HE PF16278.3 001302759.1_29522001_1 - 0.83 10.0 7.4 12 6.3 0.1 3.5 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.5 001302759.1_29522001_1 - 1 9.6 14.1 5.5 7.3 3.5 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) NinF PF05810.10 001302759.1_29522001_1 - 5.8 6.7 6.3 37 4.1 0.0 3.1 3 0 0 3 3 3 0 NinF protein Zn-ribbon_8 PF09723.8 001302759.1_29522001_1 - 6.6 6.8 19.3 0.79 9.8 0.3 4.8 3 1 2 5 5 5 0 Zinc ribbon domain WD40 PF00400.30 001284567.1_29523001_2 - 1.7e-37 126.6 22.7 2.1e-08 34.5 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001284567.1_29523001_2 - 2.1e-21 75.9 1.3 4.9e-08 33.0 0.0 6.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001284567.1_29523001_2 - 4.5e-10 39.6 0.0 0.00017 21.4 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001284567.1_29523001_2 - 1.2e-06 27.7 3.6 0.17 10.7 0.0 4.1 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.6 001284567.1_29523001_2 - 2.9e-05 22.7 2.4 0.11 11.0 0.0 2.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.14 001284567.1_29523001_2 - 3.8e-05 22.2 2.0 0.049 12.0 0.1 3.4 1 1 3 4 4 4 4 Cytochrome D1 heme domain HPS3_N PF14761.4 001284567.1_29523001_2 - 0.00032 20.3 0.0 0.072 12.6 0.0 3.0 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 GSDH PF07995.9 001284567.1_29523001_2 - 0.0056 15.9 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 1 Glucose / Sorbosone dehydrogenase PD40 PF07676.10 001284567.1_29523001_2 - 0.0097 15.7 0.2 1.9 8.4 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40_like PF17005.3 001284567.1_29523001_2 - 0.017 14.3 0.1 0.25 10.5 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.9 001284567.1_29523001_2 - 0.043 12.5 0.1 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like Frtz PF11768.6 001284567.1_29523001_2 - 0.053 11.7 0.0 0.084 11.0 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4203 PF13886.4 001283206.1_29525001_1 - 9.3e-47 159.2 29.8 1.3e-46 158.7 29.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) TPR_2 PF07719.15 001283216.1_29522001_1 - 4.1e-08 32.6 8.8 1.9e-05 24.3 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.4 001283216.1_29522001_1 - 1.5e-05 25.2 4.7 6.9e-05 23.2 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.26 001283216.1_29522001_1 - 2.6e-05 23.7 5.3 0.00057 19.5 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.4 001283216.1_29522001_1 - 0.00042 20.6 3.6 0.0016 18.8 0.5 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.4 001283216.1_29522001_1 - 0.0017 18.9 3.7 0.0076 16.8 0.2 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001283216.1_29522001_1 - 0.02 14.8 7.9 0.025 14.5 0.3 2.8 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.4 001283216.1_29522001_1 - 0.026 14.7 0.9 0.026 14.7 0.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.4 001283216.1_29522001_1 - 0.034 14.2 1.1 0.051 13.6 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.4 001283216.1_29522001_1 - 0.034 14.0 4.2 1.4 9.0 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.4 001283216.1_29522001_1 - 0.049 14.0 0.7 0.2 12.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001283216.1_29522001_1 - 0.1 12.6 4.4 0.15 12.1 0.5 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.3 001283216.1_29522001_1 - 0.11 12.4 1.2 0.18 11.7 0.2 1.8 2 0 0 2 2 2 0 Putative TPR-like repeat Arm PF00514.21 001285104.1_29526001_1 - 1.2e-43 145.7 19.9 1.2e-09 37.7 0.0 8.9 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.20 001285104.1_29526001_1 - 4.2e-14 51.3 7.5 0.025 14.7 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.5 001285104.1_29526001_1 - 3.3e-13 49.8 5.0 0.0024 17.8 0.2 4.6 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.4 001285104.1_29526001_1 - 7.3e-13 48.6 10.0 0.0008 19.6 1.3 5.2 2 2 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.4 001285104.1_29526001_1 - 2.5e-10 40.5 16.1 0.0012 19.1 0.0 6.0 6 1 0 6 6 5 3 HEAT-like repeat DNA_alkylation PF08713.9 001285104.1_29526001_1 - 2e-08 34.1 0.3 1.5 8.3 0.0 4.7 2 1 2 5 5 5 3 DNA alkylation repair enzyme Atx10homo_assoc PF09759.7 001285104.1_29526001_1 - 1.8e-05 24.6 1.3 1.8 8.5 0.0 4.8 3 2 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.7 001285104.1_29526001_1 - 0.00017 20.1 5.7 0.0043 15.5 0.8 3.0 1 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit CHASE6_C PF17150.2 001285104.1_29526001_1 - 0.06 13.9 15.3 11 6.6 0.0 6.7 8 0 0 8 8 7 0 C-terminal domain of two-partite extracellular sensor domain RTP1_C1 PF10363.7 001285104.1_29526001_1 - 0.082 12.9 1.0 0.25 11.4 0.3 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.14 001285104.1_29526001_1 - 0.92 10.2 13.8 0.58 10.9 0.1 4.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat RNA_pol_Rpc4 PF05132.12 001285104.1_29526001_3 - 0.0014 18.9 4.4 0.002 18.4 4.4 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 DUF2126 PF09899.7 001285104.1_29526001_3 - 0.17 9.8 2.8 0.22 9.5 2.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EOS1 PF12326.6 001285104.1_29526001_3 - 3.3 7.5 6.3 4.6 7.0 6.3 1.1 1 0 0 1 1 1 0 N-glycosylation protein Ribosomal_S25 PF03297.13 001285107.1_29522001_3 - 8.4e-51 170.3 4.0 1.3e-50 169.7 4.0 1.3 1 0 0 1 1 1 1 S25 ribosomal protein Mt_ATP-synt_D PF05873.10 001285107.1_29522001_3 - 0.024 14.4 0.2 0.032 14.0 0.2 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Fe_dep_repress PF01325.17 001285107.1_29522001_3 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.17 001285107.1_29522001_3 - 0.12 12.2 0.2 0.25 11.1 0.1 1.6 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB ubiquitin PF00240.21 001283740.1_29525001_1 - 1.3e-07 31.1 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.7 001283740.1_29525001_1 - 0.026 15.0 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Sulfotransfer_1 PF00685.25 001285123.1_29523001_1 - 2.5e-84 282.8 0.1 2.9e-84 282.6 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001285123.1_29523001_1 - 1.8e-09 38.2 0.0 3.4e-05 24.2 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase family Glyco_transf_8 PF01501.18 001283233.1_29524001_1 - 1e-14 54.6 0.0 1e-14 54.6 0.0 3.0 2 1 0 2 2 2 1 Glycosyl transferase family 8 7tm_1 PF00001.19 001283233.1_29524001_1 - 0.028 13.5 5.9 0.048 12.8 5.9 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Mannosyl_trans3 PF11051.6 001283233.1_29524001_1 - 0.03 13.5 0.0 0.03 13.5 0.0 1.6 2 0 0 2 2 2 0 Mannosyltransferase putative HA2 PF04408.21 001283233.1_29524001_1 - 0.16 12.3 1.2 0.5 10.6 1.2 1.8 1 0 0 1 1 1 0 Helicase associated domain (HA2) ABC_export PF16962.3 001283233.1_29524001_1 - 1.4 7.1 5.5 2 6.6 5.5 1.2 1 0 0 1 1 1 0 Putative ABC exporter NICE-3 PF07406.9 001285128.1_29524001_1 - 1.4e-76 256.3 0.0 1.9e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 NICE-3 protein 6PGD PF00393.17 001285128.1_29524001_1 - 0.083 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain CRAL_TRIO PF00650.18 001283238.1_29525001_1 - 1.9e-32 112.1 0.0 3.9e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.4 001283238.1_29525001_1 - 3.2e-07 30.4 0.0 5.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.13 001283238.1_29525001_1 - 8.2e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Inhibitor_Mig-6 PF11555.6 001283238.1_29525001_2 - 0.059 13.3 0.5 0.059 13.3 0.5 1.7 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Med20 PF08612.9 001283747.1_29526001_1 - 2e-47 161.3 0.0 2.7e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex V-SNARE_C PF12352.6 001284623.1_29524001_2 - 4.1e-20 71.7 8.0 4.1e-20 71.7 8.0 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.13 001284623.1_29524001_2 - 1.7e-18 66.6 0.4 1.7e-18 66.6 0.4 2.0 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.11 001284623.1_29524001_2 - 2e-05 24.3 1.7 5.1e-05 23.0 1.5 1.8 2 0 0 2 2 2 1 Sec20 Laminin_II PF06009.10 001284623.1_29524001_2 - 0.0034 17.3 3.3 0.27 11.1 0.8 2.7 2 1 1 3 3 3 1 Laminin Domain II YqjK PF13997.4 001284623.1_29524001_2 - 0.013 15.5 1.3 6.1 7.0 0.4 2.5 2 0 0 2 2 2 0 YqjK-like protein Fusion_gly PF00523.16 001284623.1_29524001_2 - 0.016 13.4 0.5 0.026 12.7 0.5 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF3376 PF11856.6 001284623.1_29524001_2 - 0.018 13.9 1.0 0.032 13.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) DUF745 PF05335.11 001284623.1_29524001_2 - 1.2 8.8 6.1 3.9 7.1 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) OmpH PF03938.12 001284623.1_29524001_2 - 2.3 8.1 5.4 0.64 9.9 0.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.13 001284623.1_29524001_2 - 5.6 6.3 10.0 17 4.7 10.0 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.9 001284623.1_29524001_2 - 8.3 6.9 7.6 19 5.8 2.9 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Methyltransf_3 PF01596.15 001283256.1_29522001_1 - 6.6e-56 188.7 0.0 8.6e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001283256.1_29522001_1 - 2.3e-11 44.5 0.0 3.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001283256.1_29522001_1 - 0.0012 19.3 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001283256.1_29522001_1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.17 001283256.1_29522001_1 - 0.017 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.5 001283256.1_29522001_1 - 0.046 13.5 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lipase PF00151.17 001283786.1_29525001_3 - 1.2e-130 435.5 0.0 1.8e-130 435.0 0.0 1.2 1 0 0 1 1 1 1 Lipase PLAT PF01477.21 001283786.1_29525001_3 - 1.4e-25 90.0 0.5 2.3e-25 89.3 0.5 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.5 001283786.1_29525001_3 - 0.0001 22.9 0.2 0.0001 22.9 0.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001283786.1_29525001_3 - 0.00056 19.5 0.0 0.00089 18.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold 6PF2K PF01591.16 001284631.1_29525001_3 - 2.3e-107 357.3 0.1 3.6e-107 356.6 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.20 001284631.1_29525001_3 - 2.8e-40 138.0 0.0 4.3e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.4 001284631.1_29525001_3 - 4e-07 30.1 0.0 8.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.8 001284631.1_29525001_3 - 0.00013 21.3 0.1 0.00024 20.5 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.4 001284631.1_29525001_3 - 0.071 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.20 001284631.1_29525001_3 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.10 001284631.1_29525001_3 - 0.11 11.6 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin WD40 PF00400.30 001285177.1_29524001_2 - 3.7e-33 112.9 0.4 1.2e-09 38.5 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001285177.1_29524001_2 - 3.4e-06 27.1 0.0 0.59 10.3 0.0 4.8 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001285177.1_29524001_2 - 0.036 12.9 0.0 0.37 9.6 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.3 001285177.1_29524001_2 - 0.093 11.9 0.0 0.31 10.2 0.0 1.7 1 1 0 1 1 1 0 WD40-like domain Ribosomal_S17e PF00833.16 001285177.1_29524001_3 - 0.086 12.8 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Ribosomal S17 cNMP_binding PF00027.27 001283793.1_29524001_1 - 7.7e-10 38.5 0.0 6.1e-06 26.0 0.0 3.5 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain 2-oxoacid_dh PF00198.21 001283797.1_29524001_3 - 4e-71 239.0 0.0 4.9e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.20 001283797.1_29524001_3 - 2.9e-19 68.5 0.5 2.9e-19 68.5 0.5 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.15 001283797.1_29524001_3 - 6.8e-07 29.4 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.4 001283797.1_29524001_3 - 0.0027 17.4 0.0 0.05 13.3 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like Motile_Sperm PF00635.24 001283801.1_29523001_3 - 6.7e-34 115.9 0.3 1.1e-33 115.2 0.3 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.3 001283801.1_29523001_3 - 0.0048 16.9 0.1 0.009 16.1 0.1 1.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin bZIP_1 PF00170.19 001283801.1_29523001_3 - 0.037 14.0 1.1 0.064 13.2 1.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.11 001283801.1_29523001_3 - 0.037 14.5 0.1 0.076 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GIT_CC PF16559.3 001283801.1_29523001_3 - 0.21 11.5 0.6 0.39 10.6 0.6 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ig_3 PF13927.4 001285201.1_29524001_2 - 2.4e-30 104.8 7.4 1.4e-08 35.1 0.0 6.1 5 1 1 6 6 6 5 Immunoglobulin domain C2-set_2 PF08205.10 001285201.1_29524001_2 - 5.4e-28 96.8 0.2 2.3e-20 72.3 0.0 4.0 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 001285201.1_29524001_2 - 1.2e-21 76.7 5.5 2.8e-05 24.2 0.0 4.9 5 1 0 5 5 5 4 Immunoglobulin domain I-set PF07679.14 001285201.1_29524001_2 - 1.8e-14 53.4 7.3 0.0071 16.3 0.1 7.1 5 1 0 6 6 6 4 Immunoglobulin I-set domain ig PF00047.23 001285201.1_29524001_2 - 3.2e-10 39.9 11.4 0.012 15.6 0.0 7.9 6 4 1 7 7 6 2 Immunoglobulin domain C1-set PF07654.13 001285201.1_29524001_2 - 1.1e-08 35.3 2.9 0.017 15.4 0.0 4.9 5 1 0 5 5 5 2 Immunoglobulin C1-set domain V-set PF07686.15 001285201.1_29524001_2 - 3.3e-07 30.3 10.4 0.0014 18.6 0.0 6.8 6 3 1 7 7 7 1 Immunoglobulin V-set domain DUF4366 PF14283.4 001285201.1_29524001_2 - 0.0011 18.4 0.4 0.0011 18.4 0.4 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4366) Izumo-Ig PF16706.3 001285201.1_29524001_2 - 0.015 15.2 0.1 1.6 8.7 0.0 3.3 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain PepSY_TM PF03929.14 001285201.1_29524001_2 - 0.024 13.9 0.0 0.063 12.5 0.0 1.6 1 0 0 1 1 1 0 PepSY-associated TM region DUF4604 PF15377.4 001285201.1_29524001_2 - 0.036 14.4 11.1 0.063 13.6 11.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF1191 PF06697.10 001285201.1_29524001_2 - 0.13 11.3 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1191) FixQ PF05545.9 001285201.1_29524001_2 - 0.15 11.9 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ GETHR PF05671.9 001283811.1_29525001_2 - 0.0019 17.4 13.2 15 5.0 0.1 6.3 6 0 0 6 6 6 5 GETHR pentapeptide repeat (5 copies) zf-H2C2_2 PF13465.4 001283811.1_29525001_3 - 2.9e-82 267.6 116.3 2.2e-09 37.2 1.5 13.3 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.24 001283811.1_29525001_3 - 4.6e-67 218.8 115.7 3.2e-07 30.3 2.2 13.2 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001283811.1_29525001_3 - 1.7e-31 106.0 108.2 0.0052 17.4 2.1 12.7 13 0 0 13 13 13 12 C2H2-type zinc finger KRAB PF01352.25 001283811.1_29525001_3 - 1.9e-23 81.8 0.0 3.8e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001283811.1_29525001_3 - 6.5e-12 45.0 100.0 0.016 15.0 0.3 13.2 12 1 0 12 12 12 9 C2H2-type zinc finger zinc_ribbon_15 PF17032.3 001283811.1_29525001_3 - 5.7e-05 23.7 58.8 0.84 10.3 1.9 6.4 3 1 3 6 6 6 6 zinc-ribbon family C1_1 PF00130.20 001283811.1_29525001_3 - 0.00013 21.6 55.1 0.35 10.7 1.4 8.7 1 1 11 12 12 12 8 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.8 001283811.1_29525001_3 - 0.00044 20.2 82.2 0.016 15.1 3.6 8.7 2 2 10 12 12 12 8 Zinc ribbon domain C1_4 PF07975.10 001283811.1_29525001_3 - 0.01 15.9 71.1 0.038 14.1 2.1 9.0 2 2 7 10 10 10 0 TFIIH C1-like domain DUF3268 PF11672.6 001283811.1_29525001_3 - 0.17 12.1 46.5 0.38 11.0 0.8 6.2 3 1 5 8 8 8 0 zinc-finger-containing domain p450 PF00067.20 001283290.1_29524001_2 - 1.5e-163 544.7 0.1 1.8e-163 544.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CARD PF00619.19 001284661.1_29524001_3 - 4.6e-18 64.9 0.0 6.1e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Caspase recruitment domain Trypan_PARP PF05887.9 001284661.1_29524001_3 - 0.00028 20.8 34.0 0.00045 20.1 34.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) 7tm_1 PF00001.19 001285211.1_29523001_1 - 4.3e-47 160.5 8.1 5.4e-47 160.1 8.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001285211.1_29523001_1 - 2.9e-06 27.1 1.3 4.4e-06 26.5 1.3 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.7 001285211.1_29523001_1 - 2e-05 24.0 2.6 3.3e-05 23.3 2.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001285211.1_29523001_1 - 0.0087 15.3 3.5 0.013 14.7 3.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Abhydrolase_6 PF12697.5 001284669.1_29524001_3 - 5e-24 86.0 0.0 1.4e-23 84.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001284669.1_29524001_3 - 1.3e-12 47.8 0.0 1.9e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001284669.1_29524001_3 - 9.8e-08 31.4 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.18 001284669.1_29524001_3 - 6.4e-05 23.0 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.11 001284669.1_29524001_3 - 0.0064 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.11 001284669.1_29524001_3 - 0.007 16.0 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.18 001284669.1_29524001_3 - 0.0082 15.7 0.1 0.026 14.1 0.1 1.8 1 1 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.11 001284669.1_29524001_3 - 0.031 14.0 0.1 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_2 PF02230.14 001284669.1_29524001_3 - 0.049 13.3 0.8 7.8 6.1 0.1 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.23 001284669.1_29524001_3 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PALP PF00291.23 001285214.1_29524001_1 - 1.3e-74 251.2 0.0 1.5e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ARL2_Bind_BART PF11527.6 001283820.1_29525001_2 - 8.4e-40 135.4 0.9 1.6e-39 134.5 0.9 1.5 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART CBP_BcsF PF11120.6 001283820.1_29525001_2 - 0.086 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF SUIM_assoc PF16619.3 001283820.1_29525001_2 - 2.9 7.9 10.4 1.1 9.3 1.3 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AIG1 PF04548.14 001283821.1_29523001_3 - 2.6e-80 268.6 0.0 3.9e-80 268.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.21 001283821.1_29523001_3 - 2.8e-10 40.1 0.0 6.5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.21 001283821.1_29523001_3 - 4.2e-05 23.5 2.6 0.093 12.7 0.0 3.0 2 1 1 3 3 3 2 Dynamin family FeoB_N PF02421.16 001283821.1_29523001_3 - 0.00041 19.8 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.16 001283821.1_29523001_3 - 0.0037 16.4 1.5 0.0065 15.6 0.1 1.9 2 0 0 2 2 2 1 Septin DUF258 PF03193.14 001283821.1_29523001_3 - 0.0057 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.25 001283821.1_29523001_3 - 0.0068 16.8 0.5 0.049 14.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.4 001283821.1_29523001_3 - 0.053 13.7 0.2 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1640 PF07798.9 001283821.1_29523001_3 - 0.12 12.3 2.6 0.22 11.4 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FAM184 PF15665.3 001283821.1_29523001_3 - 0.13 11.8 7.2 0.32 10.6 7.2 1.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B OmpH PF03938.12 001283821.1_29523001_3 - 0.38 10.6 5.7 0.78 9.6 5.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF87 PF01935.15 001283821.1_29523001_3 - 0.98 9.3 3.7 5.2 6.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Mitofilin PF09731.7 001283821.1_29523001_3 - 6.5 5.3 8.5 9 4.8 8.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MBOAT PF03062.17 001319461.1_29524001_3 - 4.6e-31 108.3 9.5 6.5e-31 107.8 9.5 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.9 001319461.1_29524001_3 - 0.09 13.0 0.7 0.17 12.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) MHC_I PF00129.16 001319463.1_29523001_1 - 1.3e-93 311.4 2.1 1.7e-93 311.0 2.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001319463.1_29523001_1 - 1.7e-17 63.6 0.0 3.8e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001319463.1_29523001_1 - 2.2e-12 46.5 7.3 4e-12 45.7 7.3 1.5 1 0 0 1 1 1 1 MHC_I C-terminus C2-set_2 PF08205.10 001319463.1_29523001_1 - 0.00017 21.4 1.8 0.00021 21.2 0.2 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001319463.1_29523001_1 - 0.00053 20.0 0.1 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain WH1 PF00568.21 001285218.1_29525001_3 - 3e-30 104.3 0.6 5.2e-17 61.7 0.1 2.2 2 0 0 2 2 2 2 WH1 domain VASP_tetra PF08776.9 001285218.1_29525001_3 - 9e-19 66.6 4.8 9e-19 66.6 4.8 1.8 2 0 0 2 2 2 1 VASP tetramerisation domain Kelch_1 PF01344.23 001285218.1_29525001_3 - 0.064 12.7 0.1 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Kelch motif Amidase_2 PF01510.23 001283304.1_29522001_2 - 1.7e-17 63.9 0.1 2.5e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase ER_lumen_recept PF00810.16 001285233.1_29525001_1 - 2.5e-55 187.2 8.7 5.9e-55 186.0 8.7 1.7 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.12 001285233.1_29525001_1 - 0.037 13.7 9.5 0.4 10.3 1.4 3.3 2 1 0 2 2 2 0 PQ loop repeat CD99L2 PF12301.6 001284690.1_29523001_2 - 9.7e-27 94.2 2.0 2.3e-26 93.0 1.3 1.7 1 1 1 2 2 2 2 CD99 antigen like protein 2 DARPP-32 PF05395.10 001284692.1_29522001_2 - 1.2e-38 132.7 11.1 1.8e-38 132.2 11.1 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 GFO_IDH_MocA PF01408.20 001285237.1_29525001_1 - 3.9e-12 46.9 0.0 9.8e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.15 001285237.1_29525001_1 - 0.0096 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.18 001285237.1_29525001_1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA_C PF02894.15 001285237.1_29525001_1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain HGAL PF15666.3 001283843.1_29524001_1 - 0.18 11.8 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Germinal center-associated lymphoma Pkinase PF00069.23 001283843.1_29524001_2 - 1.3e-63 214.7 0.0 1.6e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001283843.1_29524001_2 - 3.1e-38 131.4 0.0 4.1e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.22 001283843.1_29524001_2 - 2.8e-12 46.2 0.0 5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.4 001283843.1_29524001_2 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.9 001283843.1_29524001_2 - 0.17 10.8 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.17 001283326.1_29522001_1 - 4.2e-21 74.2 1.2 6.3e-21 73.7 1.2 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.4 001283326.1_29522001_1 - 3.4e-07 30.5 0.5 5.4e-07 29.9 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.30 001283326.1_29522001_1 - 4.1e-07 29.0 0.5 6.2e-06 25.3 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.4 001283326.1_29522001_1 - 8.9e-05 21.7 2.1 0.0016 17.8 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.4 001283326.1_29522001_1 - 0.00029 20.4 0.2 0.15 11.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.4 001283326.1_29522001_1 - 0.00084 18.9 0.7 0.0018 17.9 0.7 1.6 1 1 0 1 1 1 1 EF-hand domain pair p450 PF00067.20 001285268.1_29524001_1 - 4.5e-152 506.9 0.6 5.2e-152 506.7 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 Wap1 PF16997.3 001285268.1_29524001_1 - 0.0036 16.4 0.1 0.0051 15.9 0.1 1.2 1 0 0 1 1 1 1 Wap1 domain Yippee-Mis18 PF03226.12 001283347.1_29524001_3 - 3.9e-12 46.2 0.3 3.9e-12 46.2 0.3 1.6 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATPgrasp_YheCD PF14398.4 001283347.1_29524001_3 - 0.1 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 YheC/D like ATP-grasp Pkinase PF00069.23 001284722.1_29525001_1 - 2.1e-61 207.4 0.0 3.2e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001284722.1_29525001_1 - 8.1e-33 113.7 0.0 1.1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001284722.1_29525001_1 - 3.4e-09 36.3 0.0 4.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001284722.1_29525001_1 - 0.087 12.6 0.6 0.27 11.0 0.2 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.20 001283348.1_29523001_2 - 1.1e-56 190.7 0.0 1.4e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001283348.1_29523001_2 - 1.7e-21 76.5 0.0 2.3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001283348.1_29523001_2 - 2.7e-08 33.3 0.0 3.7e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001283348.1_29523001_2 - 0.12 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Actin PF00022.17 001284724.1_29524001_3 - 1.4e-150 501.3 0.0 3.7e-150 499.9 0.0 1.6 1 1 0 1 1 1 1 Actin DUF4745 PF15923.3 001283871.1_29529001_3 - 1.4e-51 173.8 1.3 3.2e-51 172.6 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4745) Sugar_tr PF00083.22 001284728.1_29525001_3 - 4.2e-26 91.7 19.4 5.2e-26 91.4 18.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.14 001284728.1_29525001_3 - 1e-20 73.8 27.6 1e-20 73.8 27.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Med17 PF10156.7 001285282.1_29525001_1 - 1.7e-10 40.1 0.6 2.6e-10 39.5 0.6 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ank_4 PF13637.4 001283887.1_29525001_2 - 3.1e-16 59.4 0.1 7.8e-11 42.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001283887.1_29525001_2 - 2e-14 53.8 0.0 5e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001283887.1_29525001_2 - 2.9e-13 49.6 0.0 1e-07 32.0 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.28 001283887.1_29525001_2 - 1.1e-11 44.4 0.2 1.1e-05 25.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.4 001283887.1_29525001_2 - 7.1e-11 41.2 0.1 1.6e-05 24.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Thioredoxin_6 PF13848.4 001284751.1_29524001_2 - 2.5e-47 161.1 0.4 1.2e-42 145.8 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.18 001284751.1_29524001_2 - 1.8e-21 75.9 0.0 3.8e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.15 001284751.1_29524001_2 - 7.7e-08 31.6 0.2 9.6e-08 31.3 0.2 1.2 1 0 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.11 001284751.1_29524001_2 - 0.00031 20.1 0.0 0.00056 19.2 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 001284751.1_29524001_2 - 0.0011 19.3 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.9 001284751.1_29524001_2 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.4 001284751.1_29524001_2 - 0.029 14.6 0.4 0.38 11.0 0.0 2.7 2 1 1 3 3 3 0 Thioredoxin-like Tubulin PF00091.23 001283898.1_29524001_2 - 4.1e-69 232.6 0.0 6.1e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001283898.1_29524001_2 - 1.1e-42 145.1 0.1 1.6e-42 144.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001283898.1_29524001_2 - 1.1e-05 25.5 0.0 2.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001283898.1_29524001_2 - 0.03 13.9 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.4 001283898.1_29524001_2 - 0.031 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin like MFS_1 PF07690.14 001283901.1_29524001_2 - 2e-07 30.1 41.8 2e-07 30.1 41.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WW PF00397.24 001283383.1_29525001_1 - 7.8e-13 48.0 11.7 1.1e-09 38.0 3.9 3.4 4 0 0 4 4 4 2 WW domain DFRP_C PF16543.3 001283911.1_29524001_1 - 1.2e-23 83.2 1.4 1.2e-23 83.2 1.4 3.9 4 1 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.22 001283911.1_29524001_1 - 1.7e-06 27.6 1.4 4.4e-06 26.3 0.9 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.3 001283911.1_29524001_1 - 1.6e-05 25.5 11.2 3.7e-05 24.2 3.3 3.1 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.3 001283911.1_29524001_1 - 0.0067 16.5 4.0 0.24 11.6 3.1 2.9 2 1 0 2 2 2 1 Zinc-finger containing family Caveolin PF01146.15 001284761.1_29523001_1 - 1.5e-59 199.6 1.6 2.5e-59 198.9 1.6 1.3 1 0 0 1 1 1 1 Caveolin BING4CT PF08149.9 001283915.1_29525001_3 - 8.1e-37 124.8 0.0 4.4e-33 112.8 0.0 3.7 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.30 001283915.1_29525001_3 - 0.00041 21.0 5.0 0.017 15.8 0.0 5.0 6 1 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001283915.1_29525001_3 - 0.0011 19.0 0.0 21 5.3 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Rpp20 PF12328.6 001283915.1_29525001_3 - 1.2 8.9 5.9 2.5 7.9 5.9 1.4 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Sedlin_N PF04628.11 001283917.1_29525001_2 - 1.5e-48 164.1 0.3 2e-48 163.7 0.3 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.10 001283917.1_29525001_2 - 5.5e-08 32.7 0.1 9.4e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Sybindin-like family UPAR_LY6_2 PF16975.3 001283398.1_29524001_3 - 1.4e-53 179.4 17.3 2.8e-53 178.4 17.3 1.5 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 SynMuv_product PF06047.9 001284806.1_29524001_3 - 8.4e-49 163.8 1.5 8.4e-49 163.8 1.5 3.1 3 0 0 3 3 3 1 Ras-induced vulval development antagonist NKAP PF15692.3 001284806.1_29524001_3 - 1e-13 51.6 15.6 1e-13 51.6 15.6 6.1 4 3 3 7 7 7 1 NF-kappa-B-activating protein GREB1 PF15782.3 001284806.1_29524001_3 - 0.34 7.9 18.5 0.45 7.4 18.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC27 PF09507.8 001284806.1_29524001_3 - 1.3 8.2 49.3 0.076 12.3 44.0 1.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Dsh_C PF12316.6 001284806.1_29524001_3 - 2.3 8.5 35.8 0.097 13.0 18.2 2.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Borrelia_P83 PF05262.9 001284806.1_29524001_3 - 3.9 5.7 31.6 0.45 8.8 27.5 1.4 2 0 0 2 2 2 0 Borrelia P83/100 protein SAP PF02037.25 001283432.1_29522001_1 - 1.6e-07 30.8 1.1 2.3e-07 30.3 1.1 1.2 1 0 0 1 1 1 1 SAP domain DUF2650 PF10853.6 001283432.1_29522001_1 - 0.0047 16.5 1.4 0.011 15.3 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) EB1 PF03271.15 001284811.1_29523001_1 - 1.3e-17 63.6 0.2 3.1e-17 62.4 0.1 1.7 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.29 001284811.1_29523001_1 - 9.7e-15 54.6 0.3 1.4e-14 54.0 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.6 001284811.1_29523001_1 - 0.027 14.2 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 CAMSAP CH domain CH_2 PF06294.9 001284811.1_29523001_1 - 0.11 12.6 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein Hormone_5 PF00184.15 001283971.1_29522001_3 - 6.3e-32 110.1 25.0 6.3e-32 110.1 25.0 1.5 2 0 0 2 2 2 1 Neurohypophysial hormones, C-terminal Domain Hormone_4 PF00220.15 001283971.1_29522001_3 - 0.00037 20.0 3.9 0.0012 18.4 3.9 2.0 1 0 0 1 1 1 1 Neurohypophysial hormones, N-terminal Domain LRR_8 PF13855.4 001283448.1_29523001_3 - 2.8e-31 106.9 61.1 5e-09 35.7 7.2 4.1 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.5 001283448.1_29523001_3 - 1.9e-18 66.0 28.8 5.6e-06 26.4 2.0 5.1 2 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001283448.1_29523001_3 - 1.4e-07 30.8 23.7 3.3 8.4 0.2 8.6 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.4 001283448.1_29523001_3 - 2.2e-05 24.0 23.8 6.5 7.0 0.4 7.5 7 0 0 7 7 7 5 Leucine Rich repeat RIO1 PF01163.20 001283450.1_29525001_1 - 9.3e-78 260.0 0.4 9.3e-78 260.0 0.4 2.2 3 0 0 3 3 3 1 RIO1 family APH PF01636.21 001283450.1_29525001_1 - 0.0024 17.7 0.0 0.041 13.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Lung_7-TM_R PF06814.11 001283984.1_29525001_2 - 9.5e-85 284.2 19.9 1.2e-84 283.8 19.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor TB2_DP1_HVA22 PF03134.17 001283466.1_29524001_2 - 1.1e-29 102.0 2.6 1.1e-29 102.0 2.6 2.0 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Phage_holin_3_6 PF07332.9 001283466.1_29524001_2 - 0.069 13.1 0.3 0.069 13.1 0.3 1.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III LSM PF01423.20 001283471.1_29523001_3 - 3.6e-18 64.9 0.4 5.5e-18 64.3 0.4 1.3 1 0 0 1 1 1 1 LSM domain NDUF_B6 PF09782.7 001283483.1_29523001_3 - 2.3e-38 131.6 1.2 3.4e-38 131.1 1.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit zf-RING_2 PF13639.4 001284858.1_29525001_1 - 5.3e-06 26.5 6.0 1.5e-05 25.1 6.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.5 001284858.1_29525001_1 - 5e-05 23.4 5.1 9.9e-05 22.4 5.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.23 001284858.1_29525001_1 - 0.0019 17.9 5.8 0.0043 16.7 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001284858.1_29525001_1 - 0.0041 16.9 6.5 0.0098 15.7 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.4 001284858.1_29525001_1 - 0.014 15.1 7.0 0.043 13.5 7.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001284858.1_29525001_1 - 0.018 14.7 4.4 0.041 13.6 4.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.5 001284858.1_29525001_1 - 0.021 14.7 4.4 0.051 13.5 4.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.3 001284858.1_29525001_1 - 0.044 13.4 4.0 0.13 11.8 4.0 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.4 001284858.1_29525001_1 - 0.047 13.6 2.0 0.14 12.1 1.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-Di19 PF05605.10 001284858.1_29525001_1 - 0.12 12.6 1.8 0.71 10.1 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.5 001284858.1_29525001_1 - 0.14 12.1 2.1 0.37 10.7 2.1 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.4 001284858.1_29525001_1 - 0.16 11.3 1.6 6.5 6.2 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_17 PF17120.3 001284858.1_29525001_1 - 0.22 11.0 6.8 0.79 9.3 6.8 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.4 001284858.1_29525001_1 - 0.43 10.6 3.2 1.1 9.3 3.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger FANCL_C PF11793.6 001284858.1_29525001_1 - 0.65 10.1 7.5 6.3 6.9 7.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Asparaginase_2 PF01112.16 001284011.1_29525001_3 - 1.7e-56 191.3 0.4 2.9e-56 190.6 0.4 1.2 1 0 0 1 1 1 1 Asparaginase TFIID-31kDa PF02291.13 001286228.1_29523001_2 - 8.6e-51 171.0 0.0 1.3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001286228.1_29523001_2 - 2.3e-07 31.3 0.3 4.8e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001286228.1_29523001_2 - 2.6e-06 27.6 0.1 5.2e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein AAA_17 PF13207.4 001286228.1_29523001_2 - 2.7e-05 24.5 0.1 2.7e-05 24.5 0.1 1.8 2 0 0 2 2 1 1 AAA domain Bromo_TP PF07524.11 001286228.1_29523001_2 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001286228.1_29523001_2 - 0.00013 22.3 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.4 001286228.1_29523001_2 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Histone PF00125.22 001286228.1_29523001_2 - 0.00032 21.0 0.3 0.00061 20.1 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001286228.1_29523001_2 - 0.0038 17.2 0.1 0.0069 16.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001286228.1_29523001_2 - 0.0066 16.7 0.3 0.013 15.8 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.4 001286228.1_29523001_2 - 0.011 15.7 0.6 0.045 13.8 0.6 2.0 1 1 0 1 1 1 0 AAA domain SKI PF01202.20 001286228.1_29523001_2 - 0.018 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.13 001286228.1_29523001_2 - 0.019 14.7 0.4 0.032 14.0 0.4 1.3 1 0 0 1 1 1 0 NTPase ADK PF00406.20 001286228.1_29523001_2 - 0.021 14.8 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 Adenylate kinase AAA_22 PF13401.4 001286228.1_29523001_2 - 0.022 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.12 001286228.1_29523001_2 - 0.042 13.7 0.2 0.096 12.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.16 001286228.1_29523001_2 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase RuvB_N PF05496.10 001286228.1_29523001_2 - 0.077 12.1 0.2 0.13 11.4 0.2 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.4 001286228.1_29523001_2 - 0.093 12.3 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.15 001286228.1_29523001_2 - 0.096 12.6 0.4 0.18 11.7 0.4 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.11 001286228.1_29523001_2 - 0.1 11.8 0.6 0.36 10.0 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_32 PF13654.4 001286228.1_29523001_2 - 0.11 11.1 0.2 0.88 8.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.21 001286228.1_29523001_2 - 0.15 12.2 0.1 0.39 10.9 0.1 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone KH_1 PF00013.27 001284017.1_29525001_3 - 0.0018 18.0 0.7 0.0042 16.8 0.7 1.6 1 0 0 1 1 1 1 KH domain IL12p40_C PF10420.7 001287275.1_29523001_3 - 5.9e-22 77.8 0.5 5.9e-22 77.8 0.5 2.1 2 0 0 2 2 2 1 Cytokine interleukin-12p40 C-terminus Ig_3 PF13927.4 001287275.1_29523001_3 - 1.1e-05 25.8 3.7 0.00038 20.9 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain Ig_5 PF16681.3 001287275.1_29523001_3 - 1.3e-05 25.4 0.2 9.6e-05 22.6 0.0 2.3 1 1 1 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_2 PF13895.4 001287275.1_29523001_3 - 1.4e-05 25.2 0.1 0.00027 21.1 0.0 2.5 1 1 1 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.3 001287275.1_29523001_3 - 0.00013 22.1 0.1 0.0007 19.8 0.0 2.2 1 1 1 2 2 2 1 T-cell surface glycoprotein CD3 delta chain fn3 PF00041.19 001287275.1_29523001_3 - 0.00014 22.0 0.2 0.00086 19.5 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III domain I-set PF07679.14 001287275.1_29523001_3 - 0.06 13.3 1.6 0.82 9.6 0.1 3.4 4 1 0 4 4 4 0 Immunoglobulin I-set domain V-set PF07686.15 001287275.1_29523001_3 - 0.29 11.2 4.1 29 4.8 0.0 3.5 3 1 1 4 4 4 0 Immunoglobulin V-set domain SNAP PF14938.4 001284026.1_29525001_3 - 4.6e-109 364.1 22.6 5.9e-109 363.7 22.6 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.4 001284026.1_29525001_3 - 9.6e-07 28.9 13.3 0.0023 18.0 0.3 3.6 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.4 001284026.1_29525001_3 - 0.0011 18.7 4.1 0.25 11.3 0.1 4.4 3 1 0 4 4 4 1 Tetratricopeptide repeat Spatacsin_C PF14649.4 001284026.1_29525001_3 - 0.019 14.0 10.9 0.38 9.7 2.5 2.4 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_1 PF00515.26 001284026.1_29525001_3 - 0.18 11.5 9.0 9.2 6.1 0.8 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.15 001284026.1_29525001_3 - 0.28 11.2 15.6 5.5 7.2 1.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.4 001284026.1_29525001_3 - 0.46 11.1 10.7 8.5 7.1 0.5 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.4 001284026.1_29525001_3 - 0.54 10.5 14.4 8 6.8 0.5 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.4 001284026.1_29525001_3 - 4.3 7.0 8.8 49 3.6 0.2 4.2 3 1 0 3 3 3 0 TPR repeat TPR_10 PF13374.4 001284026.1_29525001_3 - 5.4 6.9 8.8 11 6.0 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.4 001284026.1_29525001_3 - 5.8 7.9 10.3 26 5.9 0.1 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.4 001284026.1_29525001_3 - 8.2 7.1 7.0 12 6.6 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat 7tm_1 PF00001.19 001284030.1_29524001_2 - 6.4e-07 28.7 16.2 2.2e-06 27.0 16.2 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CECR6_TMEM121 PF14997.4 001284030.1_29524001_2 - 0.0067 16.1 2.1 0.011 15.4 2.1 1.3 1 0 0 1 1 1 1 CECR6/TMEM121 family 7TM_GPCR_Srx PF10328.7 001284030.1_29524001_2 - 0.012 14.8 7.9 0.019 14.2 7.9 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF2650 PF10853.6 001283501.1_29522001_3 - 0.0095 15.5 0.2 0.015 14.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) DUF1713 PF08213.9 001283503.1_29523001_2 - 8.7e-13 47.8 17.3 8.7e-13 47.8 17.3 2.5 3 0 0 3 3 3 1 Mitochondrial domain of unknown function (DUF1713) MAPEG PF01124.16 001283506.1_29524001_2 - 3.6e-18 65.6 3.8 5.8e-18 64.9 3.8 1.3 1 0 0 1 1 1 1 MAPEG family Annexin PF00191.18 001284044.1_29525001_1 - 2.6e-192 623.1 34.6 1.7e-26 91.9 0.9 8.1 8 0 0 8 8 8 8 Annexin Myb_DNA-bind_7 PF15963.3 001284044.1_29525001_1 - 0.00042 20.0 0.5 34 4.3 0.0 5.9 6 0 0 6 6 6 1 Myb DNA-binding like DUF2312 PF10073.7 001284044.1_29525001_1 - 0.0011 18.4 9.7 12 5.5 0.1 5.6 5 0 0 5 5 5 3 Uncharacterized protein conserved in bacteria (DUF2312) RuvC PF02075.15 001284044.1_29525001_1 - 0.0053 16.5 0.0 12 5.7 0.0 4.1 4 0 0 4 4 4 1 Crossover junction endodeoxyribonuclease RuvC DnaJ_C PF01556.16 001287310.1_29525001_1 - 1.9e-42 144.7 0.0 2.5e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 001287310.1_29525001_1 - 6.8e-28 96.5 2.7 1.2e-27 95.7 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain OLF PF02191.14 001284902.1_29524001_2 - 1.7e-74 250.4 0.0 2.1e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Prefoldin_2 PF01920.18 001284902.1_29524001_2 - 0.014 15.2 2.6 2.4 8.0 0.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.6 001284902.1_29524001_2 - 0.047 13.8 2.3 0.085 12.9 2.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GrpE PF01025.17 001284902.1_29524001_2 - 0.15 11.6 1.0 0.23 11.0 1.0 1.2 1 0 0 1 1 1 0 GrpE ERM PF00769.17 001284902.1_29524001_2 - 0.33 10.6 6.3 0.47 10.1 6.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CLZ PF16526.3 001284902.1_29524001_2 - 0.34 11.2 4.2 7 6.9 0.2 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MAD PF05557.11 001284902.1_29524001_2 - 0.4 8.8 4.5 0.56 8.3 4.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein BTB_2 PF02214.20 001284057.1_29523001_1 - 2.8e-12 46.7 0.3 4e-12 46.2 0.3 1.2 1 0 0 1 1 1 1 BTB/POZ domain HMG_box_2 PF09011.8 001284915.1_29523001_3 - 5.4e-43 145.3 16.0 7e-28 96.9 7.7 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.17 001284915.1_29523001_3 - 1.6e-42 143.6 14.3 4e-26 91.1 1.8 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.4 001284915.1_29523001_3 - 0.078 12.8 13.9 0.49 10.3 3.9 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Ets PF00178.20 001284915.1_29523001_3 - 0.23 11.9 3.2 5.4 7.4 0.4 2.3 2 0 0 2 2 2 0 Ets-domain Ribosomal_60s PF00428.17 001284915.1_29523001_3 - 2.6 8.5 19.9 7 7.1 19.9 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein 40S_SA_C PF16122.3 001284067.1_29523001_3 - 2.6e-28 99.1 21.2 4.3e-28 98.4 21.2 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S2 PF00318.18 001284067.1_29523001_3 - 1.7e-25 89.4 0.0 1.6e-12 47.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 YAF2_RYBP PF17219.1 001284923.1_29525001_3 - 1.4e-18 65.9 0.2 2.6e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.16 001284923.1_29525001_3 - 3.5e-08 32.5 2.0 1e-07 31.0 2.0 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others WTX PF09422.8 001284923.1_29525001_3 - 0.021 13.8 0.1 0.021 13.8 0.1 2.0 1 1 0 2 2 2 0 WTX protein GCV_T PF01571.19 001287329.1_29525001_1 - 1e-84 283.8 0.0 1.3e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.9 001287329.1_29525001_1 - 2.5e-22 78.8 0.0 4.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAM212 PF15342.4 001283550.1_29524001_2 - 2.5e-28 97.5 0.6 1.3e-26 92.0 0.3 2.4 2 0 0 2 2 2 2 FAM212 family HS1_rep PF02218.13 001283552.1_29525001_3 - 1.9e-68 226.4 34.6 1.5e-19 70.0 5.9 5.4 5 0 0 5 5 5 4 Repeat in HS1/Cortactin SH3_1 PF00018.26 001283552.1_29525001_3 - 1.6e-16 59.5 0.1 1.6e-16 59.5 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.4 001283552.1_29525001_3 - 6.9e-16 57.7 0.3 1.4e-15 56.8 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 001283552.1_29525001_3 - 4.8e-08 32.5 0.0 1.3e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.4 001283552.1_29525001_3 - 0.0054 17.0 0.5 15 5.9 0.0 3.9 1 1 3 4 4 4 1 TMEM210 family IFNGR1 PF07140.9 001284940.1_29525001_1 - 1.7e-45 154.3 8.4 3.2e-45 153.4 8.4 1.4 1 0 0 1 1 1 1 Interferon gamma receptor (IFNGR1) Tissue_fac PF01108.15 001284940.1_29525001_1 - 1.9e-21 75.7 0.1 5.1e-21 74.4 0.1 1.7 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001284940.1_29525001_1 - 1.7e-08 34.5 1.1 4e-08 33.4 1.1 1.6 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III COMM_domain PF07258.12 001284090.1_29523001_1 - 1.4e-16 60.2 0.4 1.4e-16 60.2 0.4 2.2 2 0 0 2 2 2 1 COMM domain Homeobox PF00046.27 001287619.1_29524001_2 - 1.5e-21 75.8 8.0 3.4e-21 74.7 8.0 1.6 1 0 0 1 1 1 1 Homeobox domain DUF2209 PF09974.7 001287619.1_29524001_2 - 0.23 11.7 0.1 0.35 11.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) DSPc PF00782.18 001284094.1_29523001_2 - 7.4e-35 119.5 0.0 1.1e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001284094.1_29523001_2 - 0.00064 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.4 001284094.1_29523001_2 - 0.012 15.7 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate EOS1 PF12326.6 001283564.1_29525001_1 - 0.11 12.3 2.6 0.16 11.7 2.6 1.4 1 0 0 1 1 1 0 N-glycosylation protein Sushi PF00084.18 001283564.1_29525001_3 - 1.3e-66 220.9 46.2 3.5e-11 43.4 0.1 7.4 6 1 1 7 7 7 7 Sushi repeat (SCR repeat) DUF3405 PF11885.6 001283564.1_29525001_3 - 0.68 8.3 7.3 0.85 8.0 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Presenilin PF01080.15 001283564.1_29525001_3 - 0.78 8.3 6.3 1.1 7.8 6.3 1.2 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.6 001283564.1_29525001_3 - 1.3 8.8 4.9 1.8 8.3 4.9 1.3 1 0 0 1 1 1 0 N-glycosylation protein Ras PF00071.20 001284098.1_29524001_3 - 2.2e-36 124.8 0.0 3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001284098.1_29524001_3 - 6e-25 87.7 0.0 8.8e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001284098.1_29524001_3 - 2.9e-11 43.0 0.0 4.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001284098.1_29524001_3 - 0.00017 20.9 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF2045 PF09741.7 001284101.1_29525001_2 - 2.5e-100 334.7 0.5 3.3e-100 334.3 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) Paf1 PF03985.11 001283573.1_29525001_2 - 8.5e-150 499.3 23.6 8.5e-150 499.3 23.6 2.2 1 1 1 2 2 2 1 Paf1 MPC PF03650.11 001283575.1_29522001_1 - 2.7e-33 114.3 0.2 4.3e-33 113.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MPP6 PF10175.7 001193603.1_29622001_2 - 5e-42 143.4 4.9 6.2e-42 143.1 4.9 1.1 1 0 0 1 1 1 1 M-phase phosphoprotein 6 CRF-BP PF05428.9 001193603.1_29622001_2 - 0.17 10.5 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) TPR_12 PF13424.4 001266031.1_29627001_1 - 1.2e-17 63.8 20.1 6.1e-05 23.1 0.0 5.6 3 2 1 5 5 5 5 Tetratricopeptide repeat SHNi-TPR PF10516.7 001266031.1_29627001_1 - 3.2e-09 35.9 0.2 0.0014 17.9 0.0 4.1 4 0 0 4 4 4 3 SHNi-TPR TPR_2 PF07719.15 001266031.1_29627001_1 - 1.5e-06 27.7 16.8 0.34 11.0 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.4 001266031.1_29627001_1 - 0.00023 20.8 3.4 13 5.7 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF3856 PF12968.5 001266031.1_29627001_1 - 0.0086 16.0 0.4 0.051 13.5 0.3 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) Hat1_N PF10394.7 001266031.1_29627001_1 - 0.049 13.7 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus TPR_1 PF00515.26 001266031.1_29627001_1 - 0.22 11.2 11.2 3.2 7.6 0.9 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.4 001266031.1_29627001_1 - 4.1 7.7 10.8 15 6.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat HPD PF05044.10 001260873.1_29626001_1 - 2.7e-83 277.4 2.2 4.7e-83 276.6 2.2 1.4 1 0 0 1 1 1 1 Homeo-prospero domain NifQ PF04891.10 001260873.1_29626001_1 - 0.035 14.3 3.7 0.58 10.4 0.0 3.3 3 0 0 3 3 3 0 NifQ Metal_resist PF13801.4 001260873.1_29626001_1 - 0.06 13.4 9.8 0.12 12.4 8.6 2.0 2 0 0 2 2 2 0 Heavy-metal resistance PP_kinase_N PF13089.4 001260873.1_29626001_1 - 0.56 10.4 8.9 3.9 7.7 4.7 3.6 3 1 0 3 3 3 0 Polyphosphate kinase N-terminal domain DUF2968 PF11180.6 001260873.1_29626001_1 - 0.57 9.7 16.0 1.1 8.8 16.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Exonuc_VII_L PF02601.13 001260873.1_29626001_1 - 0.63 9.4 7.2 1.2 8.6 7.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4613 PF15390.4 001260873.1_29626001_1 - 1.5 7.0 7.5 2.3 6.3 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF342 PF03961.11 001260873.1_29626001_1 - 1.7 7.0 4.0 2.7 6.4 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-CpG_bind_C PF12269.6 001260873.1_29626001_1 - 1.9 8.1 7.4 4 7.0 7.4 1.5 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain FliD_N PF02465.16 001260873.1_29626001_1 - 2 9.0 5.4 15 6.2 5.5 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Nop25 PF09805.7 001260873.1_29626001_1 - 7.3 6.9 19.4 16 5.8 19.4 1.5 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) UPF0029 PF01205.17 001266051.1_29625001_2 - 9.1e-34 115.8 0.0 1.3e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.20 001266051.1_29625001_2 - 1.5e-17 63.8 0.3 2.5e-17 63.1 0.3 1.4 1 0 0 1 1 1 1 RWD domain SKA2 PF16740.3 001266054.1_29624001_3 - 5.2e-37 125.9 5.6 6.8e-37 125.5 5.6 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Ig_J_chain PF15097.4 001260886.1_29623001_3 - 5.5e-74 246.3 8.0 7.2e-74 245.9 8.0 1.1 1 0 0 1 1 1 1 Immunoglobulin J chain RTP1_C1 PF10363.7 001260886.1_29623001_3 - 0.0041 17.1 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 AAA_2 PF07724.12 001260887.1_29625001_1 - 1.1e-41 142.7 0.0 2e-41 141.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.7 001260887.1_29625001_1 - 1.8e-14 53.4 0.1 4.1e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.27 001260887.1_29625001_1 - 1.3e-13 51.3 0.0 2.5e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.12 001260887.1_29625001_1 - 1.6e-05 24.8 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.24 001260887.1_29625001_1 - 2e-05 24.2 0.3 0.00018 21.1 0.0 2.4 2 1 0 2 2 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.19 001260887.1_29625001_1 - 9.7e-05 21.7 0.0 0.012 14.9 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.4 001260887.1_29625001_1 - 0.00036 20.7 0.1 0.0014 18.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.4 001260887.1_29625001_1 - 0.0022 18.0 0.0 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.4 001260887.1_29625001_1 - 0.0036 17.6 0.0 0.0093 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.4 001260887.1_29625001_1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.15 001260887.1_29625001_1 - 0.0086 15.7 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.18 001260887.1_29625001_1 - 0.0092 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein RuvB_N PF05496.10 001260887.1_29625001_1 - 0.01 15.0 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TsaE PF02367.15 001260887.1_29625001_1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.10 001260887.1_29625001_1 - 0.032 14.0 0.3 0.084 12.7 0.3 1.8 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.4 001260887.1_29625001_1 - 0.062 13.7 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.4 001260887.1_29625001_1 - 0.068 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.25 001260887.1_29625001_1 - 0.075 13.4 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.11 001260887.1_29625001_1 - 0.13 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_29 PF13555.4 001260887.1_29625001_1 - 0.15 11.6 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zinc_ribbon_4 PF13717.4 001260887.1_29625001_1 - 0.28 11.0 4.9 10 6.0 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.5 001260887.1_29625001_1 - 0.45 10.4 4.6 0.99 9.3 4.6 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Arf PF00025.19 001195582.1_29623001_2 - 2.3e-74 248.5 0.3 3e-74 248.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001195582.1_29623001_2 - 5.9e-14 51.8 0.0 7.9e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.20 001195582.1_29623001_2 - 2.2e-13 50.0 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001195582.1_29623001_2 - 3e-13 49.9 0.0 4.5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.18 001195582.1_29623001_2 - 3.4e-10 39.5 1.9 5.2e-07 29.0 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.10 001195582.1_29623001_2 - 9.6e-10 38.1 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001195582.1_29623001_2 - 0.00078 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 001195582.1_29623001_2 - 0.027 13.6 0.1 0.045 12.9 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CUB PF00431.18 001266059.1_29625001_1 - 3.7e-40 136.6 0.1 6.6e-26 90.7 0.0 3.2 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.16 001266059.1_29625001_1 - 8e-07 29.0 3.5 8e-07 29.0 3.5 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A zf-RING_2 PF13639.4 001266064.1_29623001_3 - 1.1e-11 44.6 8.0 1.1e-11 44.6 8.0 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.3 001266064.1_29623001_3 - 2.4e-10 39.8 1.2 5.7e-10 38.6 1.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.23 001266064.1_29623001_3 - 4.3e-07 29.6 6.5 4.3e-07 29.6 6.5 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001266064.1_29623001_3 - 4.3e-07 30.0 9.9 2.1e-06 27.8 9.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.4 001266064.1_29623001_3 - 6.2e-07 29.2 4.7 2e-06 27.6 4.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.4 001266064.1_29623001_3 - 1.3e-06 28.0 8.7 1.3e-06 28.0 8.7 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001266064.1_29623001_3 - 3.4e-05 23.5 5.4 3.4e-05 23.5 5.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001266064.1_29623001_3 - 5.6e-05 22.9 6.6 5.6e-05 22.9 6.6 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 001266064.1_29623001_3 - 0.00054 19.8 3.1 0.00054 19.8 3.1 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.4 001266064.1_29623001_3 - 0.12 12.1 7.3 0.09 12.6 2.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.6 001266064.1_29623001_3 - 0.44 10.6 8.0 11 6.2 8.0 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.3 001266064.1_29623001_3 - 0.63 10.0 5.5 2.1 8.3 5.5 1.9 1 0 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.4 001266064.1_29623001_3 - 6 6.7 16.1 0.028 14.2 6.6 2.0 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 UCH PF00443.27 001266070.1_29624001_1 - 9.6e-62 208.6 0.2 1.5e-61 208.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 001266070.1_29624001_1 - 3e-23 82.8 0.0 3.8e-22 79.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.17 001266070.1_29624001_1 - 4.5e-20 71.6 14.4 4.5e-20 71.6 14.4 2.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Pentapeptide PF00805.20 001260902.1_29625001_1 - 1.7e-34 116.9 23.8 2.7e-12 46.0 1.9 4.5 2 2 1 4 4 4 4 Pentapeptide repeats (8 copies) BTB_2 PF02214.20 001260902.1_29625001_1 - 7e-20 71.1 0.0 1.2e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_4 PF13599.4 001260902.1_29625001_1 - 6.1e-19 67.8 0.7 1.5e-09 37.7 0.0 3.1 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) KHA PF11834.6 001260902.1_29625001_1 - 7.8e-18 64.2 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Pentapeptide_3 PF13576.4 001260902.1_29625001_1 - 1.3e-11 44.3 0.0 2.1e-05 24.5 0.0 4.0 2 1 0 3 3 3 3 Pentapeptide repeats (9 copies) BTB PF00651.29 001260902.1_29625001_1 - 0.00018 21.5 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.3 001260902.1_29625001_1 - 0.0003 20.7 0.0 0.00056 19.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.30 001266073.1_29624001_1 - 1e-11 45.1 3.5 0.00024 21.7 0.2 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001266073.1_29624001_1 - 5.1e-08 33.0 0.0 0.61 10.3 0.0 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.10 001266073.1_29624001_1 - 0.00025 20.7 0.2 0.97 9.3 0.0 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.3 001266073.1_29624001_1 - 0.025 13.4 0.0 0.067 12.0 0.0 1.7 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.9 001266073.1_29624001_1 - 0.062 13.0 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A 5-FTHF_cyc-lig PF01812.18 001266078.1_29622001_3 - 4.6e-62 209.0 0.0 5.4e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family START PF01852.17 001260912.1_29627001_1 - 1.7e-17 63.4 1.3 2.9e-17 62.6 1.3 1.3 1 0 0 1 1 1 1 START domain GST_C PF00043.23 001195776.1_29622001_2 - 9.1e-20 70.5 0.0 1.5e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001195776.1_29622001_2 - 1.1e-19 70.3 0.0 1.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001195776.1_29622001_2 - 7.2e-19 67.8 0.0 1.3e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001195776.1_29622001_2 - 0.0096 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3825 PF12873.5 001195776.1_29622001_2 - 0.14 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) GST_C_3 PF14497.4 001195777.1_29622001_3 - 4.6e-20 71.5 0.0 8.8e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001195777.1_29622001_3 - 1.3e-19 70.2 0.0 2.8e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001195777.1_29622001_3 - 8e-19 67.5 0.0 1.3e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001195777.1_29622001_3 - 0.01 16.1 0.0 0.04 14.2 0.0 1.9 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain PCNA_C PF02747.13 001266090.1_29623001_1 - 8.3e-63 210.1 0.0 1.4e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.16 001266090.1_29623001_1 - 5.7e-60 200.5 2.1 1.1e-59 199.6 2.1 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.14 001266090.1_29623001_1 - 1.4e-09 37.3 0.2 3.4e-09 36.0 0.2 1.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.11 001266090.1_29623001_1 - 2.6e-07 30.2 0.1 3.7e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Rad9 Med30 PF11315.6 001266097.1_29622001_2 - 3.8e-64 215.2 0.9 4.4e-64 215.0 0.9 1.0 1 0 0 1 1 1 1 Mediator complex subunit 30 APG17 PF04108.10 001266097.1_29622001_2 - 0.016 14.2 0.2 0.058 12.4 0.1 1.7 2 0 0 2 2 2 0 Autophagy protein Apg17 Med21 PF11221.6 001266097.1_29622001_2 - 0.058 13.5 6.7 2.1 8.5 0.2 2.7 3 0 0 3 3 3 0 Subunit 21 of Mediator complex NPV_P10 PF05531.10 001266097.1_29622001_2 - 0.075 13.4 0.9 1.9 8.9 0.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0449 PF15136.4 001266097.1_29622001_2 - 0.11 12.8 0.8 0.25 11.7 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4200 PF13863.4 001266097.1_29622001_2 - 0.12 12.6 3.9 0.16 12.2 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) NYD-SP28_assoc PF14775.4 001266097.1_29622001_2 - 0.6 10.1 4.4 1.3 9.1 4.4 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Sin3a_C PF16879.3 001266100.1_29629001_3 - 3.3e-100 335.4 9.8 3.3e-100 335.4 9.8 2.0 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.19 001266100.1_29629001_3 - 1.8e-49 165.5 5.3 7.5e-19 67.5 0.0 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.10 001266100.1_29629001_3 - 5.3e-42 141.7 0.2 1.2e-41 140.6 0.2 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor Ras PF00071.20 001198678.1_29623001_1 - 1.9e-56 190.0 0.3 2.5e-56 189.6 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001198678.1_29623001_1 - 5.6e-20 71.6 0.0 9.6e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001198678.1_29623001_1 - 4.5e-08 32.6 0.1 6.1e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001198678.1_29623001_1 - 0.00056 19.4 0.2 0.0011 18.4 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001198678.1_29623001_1 - 0.0036 17.2 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001198678.1_29623001_1 - 0.015 15.1 2.1 3 7.6 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF258 G-alpha PF00503.18 001198678.1_29623001_1 - 0.028 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Rad60-SLD PF11976.6 001198691.2_29622001_1 - 4.2e-25 87.3 0.1 5.7e-25 86.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.21 001198691.2_29622001_1 - 3.2e-11 42.6 0.1 4.8e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family NNMT_PNMT_TEMT PF01234.15 001266113.1_29622001_1 - 9.1e-102 339.5 0.0 1e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family eIF-5a PF01287.18 001260939.1_29624001_1 - 3.6e-26 90.9 0.1 5.7e-26 90.3 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.10 001260939.1_29624001_1 - 0.022 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Arrestin_N PF00339.27 001260940.1_29624001_3 - 2.8e-36 124.7 0.1 4e-35 120.9 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 001260940.1_29624001_3 - 1.6e-21 77.0 0.0 1.3e-17 64.3 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.13 001260940.1_29624001_3 - 0.005 15.7 0.0 0.014 14.2 0.0 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 zf-C2H2 PF00096.24 001260941.1_29629001_1 - 6.9e-11 41.8 76.4 0.019 15.3 3.3 10.0 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001260941.1_29629001_1 - 3.3e-09 36.7 76.9 0.017 15.7 3.2 10.9 10 0 0 10 10 10 7 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001260941.1_29629001_1 - 3.7e-06 27.0 71.7 0.00052 20.2 2.0 11.7 13 0 0 13 13 13 5 Zinc-finger double domain zf-H2C2_5 PF13909.4 001260941.1_29629001_1 - 0.0025 17.4 75.0 0.078 12.6 1.0 9.3 9 0 0 9 9 9 6 C2H2-type zinc-finger domain DUF5069 PF16798.3 001260941.1_29629001_1 - 0.062 13.4 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) zf-C2HE PF16278.3 001260941.1_29629001_1 - 0.074 13.4 0.1 0.074 13.4 0.1 5.6 5 1 0 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CSL PF05207.11 001260941.1_29629001_1 - 0.084 12.5 3.6 0.069 12.8 0.3 2.4 2 0 0 2 2 2 0 CSL zinc finger Fibrinogen_C PF00147.16 001266116.1_29628001_1 - 2e-69 233.6 5.8 3e-69 233.1 5.8 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4239 PF14023.4 001266116.1_29628001_1 - 0.89 9.1 7.3 0.62 9.7 5.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) IL8 PF00048.18 001032879.1_29621001_1 - 8.3e-14 51.4 0.8 1e-13 51.1 0.8 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Ribosomal_L28e PF01778.15 001266119.1_29622001_2 - 1.5e-35 122.2 1.8 2.1e-35 121.8 1.8 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family MipZ PF09140.9 001266119.1_29622001_2 - 0.002 17.3 0.1 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 ATPase MipZ HSP20 PF00011.19 001260949.2_29622001_3 - 6.3e-25 87.1 0.0 9.1e-25 86.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YabP PF07873.9 001260949.2_29622001_3 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 YabP family Homeobox PF00046.27 001266139.1_29623001_2 - 1.6e-21 75.7 2.4 3.3e-21 74.7 2.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001266139.1_29623001_2 - 0.031 14.0 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 Homeobox KN domain EF-hand_1 PF00036.30 001266140.1_29627001_2 - 1.7e-10 39.5 0.0 0.0063 15.9 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.4 001266140.1_29627001_2 - 1.9e-10 40.2 0.0 1e-07 31.5 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.4 001266140.1_29627001_2 - 5.8e-08 31.9 0.0 0.046 13.5 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.4 001266140.1_29627001_2 - 1.4e-06 28.6 0.0 0.078 13.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001266140.1_29627001_2 - 4.2e-05 22.8 0.1 0.85 9.1 0.0 3.5 3 0 0 3 3 3 2 EF hand PTEN_C2 PF10409.7 001260965.1_29629001_2 - 2.4e-46 156.7 2.5 3.9e-46 156.0 2.5 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.18 001260965.1_29629001_2 - 3.9e-07 29.8 0.0 1.3e-06 28.1 0.0 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001260965.1_29629001_2 - 0.00096 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.4 001260965.1_29629001_2 - 0.013 15.3 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.4 001260965.1_29629001_2 - 0.028 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF3256 PF11644.6 001260965.1_29629001_2 - 0.092 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) BTB PF00651.29 001266147.1_29629001_2 - 2.3e-23 82.4 0.0 3.9e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.4 001266147.1_29629001_2 - 4.8e-11 42.5 47.3 1e-06 28.8 5.2 9.7 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2 PF00096.24 001266147.1_29629001_2 - 0.0015 18.8 9.3 0.0079 16.5 3.6 9.3 10 0 0 10 10 10 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001266147.1_29629001_2 - 0.025 15.3 78.0 0.51 11.2 0.7 10.5 10 0 0 10 10 10 0 C2H2-type zinc finger BolA PF01722.16 001266147.1_29629001_2 - 0.058 13.6 2.1 3.6 7.8 0.1 3.1 2 1 1 3 3 3 0 BolA-like protein Elf1 PF05129.11 001266147.1_29629001_2 - 0.53 10.2 21.9 0.48 10.4 2.0 4.7 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like IRS PF02174.15 001266155.1_29625001_3 - 1.5e-29 101.7 0.0 2.6e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.27 001266155.1_29625001_3 - 8.2e-05 22.9 0.3 0.00015 22.1 0.3 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 001266155.1_29625001_3 - 0.02 15.1 1.0 0.092 13.0 1.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain RGM_C PF06534.11 001266155.1_29625001_3 - 0.022 14.1 0.2 0.039 13.3 0.2 1.3 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus XLF PF09302.9 001245955.1_29622001_1 - 1.6e-37 129.2 0.3 2.6e-37 128.6 0.3 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component HAD_2 PF13419.4 001266157.1_29623001_3 - 1.4e-26 93.6 0.0 4.7e-26 91.8 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.24 001266157.1_29623001_3 - 1.4e-14 54.7 0.0 7.6e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.4 001266157.1_29623001_3 - 2e-10 40.5 0.0 5.6e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like DUF705 PF05152.10 001266157.1_29623001_3 - 0.028 13.7 0.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF705) PcrB PF01884.15 001266157.1_29623001_3 - 0.066 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 PcrB family HAD PF12710.5 001266157.1_29623001_3 - 0.11 12.8 0.1 0.18 12.0 0.1 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cyclin_N2 PF16500.3 001266158.1_29626001_3 - 2.4e-49 167.5 2.8 3.6e-49 166.9 2.8 1.2 1 0 0 1 1 1 1 N-terminal region of cyclin_N Cyclin_N PF00134.21 001266158.1_29626001_3 - 4.6e-48 162.1 0.3 7.6e-48 161.4 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001266158.1_29626001_3 - 1.7e-26 92.5 0.2 4.3e-26 91.2 0.1 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Sororin PF09666.8 001266158.1_29626001_3 - 0.025 14.7 3.2 0.041 14.0 3.2 1.3 1 0 0 1 1 1 0 Sororin protein Peptidase_C12 PF01088.19 001266166.1_29622001_2 - 4.3e-68 229.0 0.1 5e-68 228.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 YAF2_RYBP PF17219.1 001266167.1_29625001_1 - 1.4e-18 65.9 0.2 2.5e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.16 001266167.1_29625001_1 - 3.8e-08 32.4 2.0 9.8e-08 31.1 2.0 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others WTX PF09422.8 001266167.1_29625001_1 - 0.022 13.7 0.1 0.022 13.7 0.1 2.0 1 1 0 2 2 2 0 WTX protein ABC_membrane PF00664.21 001032930.1_29629001_3 - 1.5e-63 214.9 37.4 4.5e-32 111.7 14.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001032930.1_29629001_3 - 1.7e-49 167.7 0.6 7.9e-30 104.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.17 001032930.1_29629001_3 - 1.1e-07 31.4 6.6 0.0032 16.8 0.8 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.21 001032930.1_29629001_3 - 5.9e-07 29.4 1.7 0.0085 16.0 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.14 001032930.1_29629001_3 - 7.7e-07 29.0 0.2 0.016 15.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.4 001032930.1_29629001_3 - 9.8e-06 25.1 0.6 0.1 12.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.4 001032930.1_29629001_3 - 3.2e-05 24.2 0.1 0.27 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.10 001032930.1_29629001_3 - 0.00019 20.7 1.1 0.095 11.8 0.2 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.4 001032930.1_29629001_3 - 0.00039 20.2 3.2 12 5.5 0.2 4.3 2 2 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.4 001032930.1_29629001_3 - 0.0023 18.1 2.1 1.9 8.6 1.0 3.4 2 1 0 2 2 2 1 AAA domain ArgK PF03308.14 001032930.1_29629001_3 - 0.004 16.0 0.5 0.061 12.2 0.1 2.2 2 0 0 2 2 2 1 ArgK protein AAA_23 PF13476.4 001032930.1_29629001_3 - 0.0053 17.2 7.1 0.26 11.6 0.1 3.6 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.4 001032930.1_29629001_3 - 0.0077 15.8 2.5 1.2 8.7 0.2 3.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.21 001032930.1_29629001_3 - 0.0087 16.0 7.5 0.018 14.9 1.1 2.9 3 0 0 3 3 2 1 Dynamin family AAA_25 PF13481.4 001032930.1_29629001_3 - 0.0092 15.4 0.2 0.15 11.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.18 001032930.1_29629001_3 - 0.017 14.1 0.4 5.5 5.8 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.7 001032930.1_29629001_3 - 0.021 13.6 2.2 0.82 8.4 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.15 001032930.1_29629001_3 - 0.025 14.5 8.5 0.066 13.1 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.5 001032930.1_29629001_3 - 0.029 13.2 0.6 0.13 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.24 001032930.1_29629001_3 - 0.046 13.3 2.0 4.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain NB-ARC PF00931.20 001032930.1_29629001_3 - 0.055 12.4 3.5 4.4 6.1 0.2 2.8 3 0 0 3 3 3 0 NB-ARC domain AKAP28 PF14469.4 001032930.1_29629001_3 - 0.081 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 28 kDa A-kinase anchor FtsK_SpoIIIE PF01580.16 001032930.1_29629001_3 - 0.12 11.5 0.3 11 5.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.17 001032930.1_29629001_3 - 0.26 10.7 1.7 4.1 6.8 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.14 001032930.1_29629001_3 - 0.28 10.3 2.9 11 5.1 0.1 3.0 3 0 0 3 3 3 0 AIG1 family LRR_6 PF13516.4 001260995.1_29626001_2 - 2.9e-08 33.0 3.6 0.11 12.4 0.1 5.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.5 001260995.1_29626001_2 - 0.0095 16.2 10.2 2 8.8 0.2 4.8 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001260995.1_29626001_2 - 0.32 11.5 11.3 0.58 10.7 0.1 5.6 7 0 0 7 7 7 0 Leucine Rich Repeat UCH PF00443.27 001260999.2_29626001_3 - 1.4e-51 175.4 10.4 1.4e-51 175.4 10.4 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.17 001260999.2_29626001_3 - 9.5e-21 73.8 11.9 9.5e-21 73.8 11.9 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.4 001260999.2_29626001_3 - 5.2e-18 65.6 15.5 6.6e-16 58.7 15.5 3.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DapB_C PF05173.12 001260999.2_29626001_3 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus zinc_ribbon_10 PF10058.7 001260999.2_29626001_3 - 0.23 11.1 4.8 0.17 11.5 0.5 2.8 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Vinculin PF01044.17 001257368.1_29628001_2 - 0 1040.0 36.2 3.2e-215 717.3 24.5 2.1 1 1 1 2 2 2 2 Vinculin family I_LWEQ PF01608.15 001257368.1_29628001_2 - 0.2 11.7 0.1 0.2 11.7 0.1 6.7 4 4 2 6 6 6 0 I/LWEQ domain Rotamase PF00639.19 001257368.1_29628001_2 - 0.38 11.6 9.8 3.1 8.7 0.1 4.4 4 0 0 4 4 4 0 PPIC-type PPIASE domain Ribosomal_S17 PF00366.18 001266196.2_29622001_3 - 2.9e-18 65.6 0.0 5.3e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 LRR_8 PF13855.4 001261023.1_29626001_3 - 1.4e-52 175.1 76.6 2.7e-12 46.1 7.9 9.2 5 3 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.5 001261023.1_29626001_3 - 2.4e-39 132.4 83.0 2.7e-07 30.6 3.1 12.0 4 3 8 14 14 14 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001261023.1_29626001_3 - 4.4e-07 29.3 72.7 0.72 10.4 0.2 17.4 17 2 2 19 19 19 5 Leucine Rich Repeat LRR_9 PF14580.4 001261023.1_29626001_3 - 1.1e-05 24.9 38.1 0.0092 15.4 2.2 5.9 2 2 4 6 6 6 6 Leucine-rich repeat LRR_5 PF13306.4 001261023.1_29626001_3 - 0.0054 16.5 11.7 0.012 15.5 0.7 4.2 3 1 1 4 4 4 1 Leucine rich repeats (6 copies) Popeye PF04831.11 001266212.1_29624001_3 - 5.1e-45 153.0 0.8 7.4e-45 152.4 0.8 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.27 001266212.1_29624001_3 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain UDPGT PF00201.16 001033027.1_29624001_1 - 5.3e-261 866.5 0.5 6.2e-261 866.3 0.5 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001033027.1_29624001_1 - 2.1e-07 30.9 0.0 4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.4 001033027.1_29624001_1 - 0.00031 20.7 0.0 0.0025 17.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Nfu_N PF08712.9 001033027.1_29624001_1 - 0.0042 17.0 0.1 4.4 7.3 0.0 2.8 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal Glyco_trans_4_4 PF13579.4 001033027.1_29624001_1 - 0.02 15.2 0.0 0.055 13.8 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain FCH PF00611.21 001266225.1_29624001_2 - 4.9e-16 58.6 0.1 4.9e-16 58.6 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.4 001266225.1_29624001_2 - 1.2e-14 53.8 0.1 2.4e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001266225.1_29624001_2 - 2.8e-12 45.9 1.5 3.6e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.15 001266225.1_29624001_2 - 1.5e-06 27.7 0.0 3.7e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain GrpE PF01025.17 001266225.1_29624001_2 - 0.0051 16.4 5.8 0.0051 16.4 5.8 1.8 1 1 1 2 2 2 1 GrpE DUF842 PF05811.11 001266225.1_29624001_2 - 0.021 14.5 4.2 0.042 13.5 4.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tho2 PF11262.6 001266225.1_29624001_2 - 0.38 9.8 5.6 0.56 9.2 5.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3450 PF11932.6 001266225.1_29624001_2 - 0.5 9.5 9.7 0.8 8.8 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Mnd1 PF03962.13 001266225.1_29624001_2 - 1.6 8.4 9.2 2.9 7.6 9.2 1.4 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.7 001266225.1_29624001_2 - 2.5 7.0 11.0 3.8 6.4 11.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.13 001266225.1_29624001_2 - 4.5 6.6 6.8 6.6 6.1 6.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.11 001266225.1_29624001_2 - 8 5.5 7.5 12 4.9 7.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein Glyco_transf_29 PF00777.16 001266232.1_29625001_1 - 1.3e-75 254.1 0.0 1.7e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) TPR_1 PF00515.26 001257451.1_29628001_2 - 1.6e-37 125.6 17.9 4.4e-08 32.5 0.2 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.15 001257451.1_29628001_2 - 3.1e-28 95.5 18.8 2e-06 27.4 0.5 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat RPAP3_C PF13877.4 001257451.1_29628001_2 - 3.7e-25 88.1 1.6 8.7e-25 87.0 1.6 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.4 001257451.1_29628001_2 - 6.4e-20 69.5 14.7 0.0011 18.8 0.2 7.2 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_11 PF13414.4 001257451.1_29628001_2 - 2e-16 59.3 13.1 3.1e-06 26.6 0.1 5.0 3 2 3 6 6 6 3 TPR repeat TPR_7 PF13176.4 001257451.1_29628001_2 - 2.5e-11 42.6 7.2 0.0014 18.4 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.4 001257451.1_29628001_2 - 3.8e-09 36.6 9.8 0.28 11.3 0.5 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.4 001257451.1_29628001_2 - 4.9e-09 36.1 0.9 0.075 13.8 0.2 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.4 001257451.1_29628001_2 - 5.1e-09 36.5 3.0 0.11 13.1 0.1 4.4 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.4 001257451.1_29628001_2 - 8.5e-09 35.7 5.1 0.032 14.6 0.6 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.4 001257451.1_29628001_2 - 4.7e-06 26.5 0.6 0.12 12.4 0.1 3.8 2 2 2 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001257451.1_29628001_2 - 3.9e-05 23.5 9.0 0.11 12.5 0.0 4.6 5 0 0 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.4 001257451.1_29628001_2 - 0.00043 20.4 13.8 4.6 7.7 0.1 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.4 001257451.1_29628001_2 - 0.0062 17.0 10.0 1.2 9.8 0.3 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat NRBF2_MIT PF17169.2 001257451.1_29628001_2 - 0.0097 16.0 0.5 5.1 7.3 0.0 2.8 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 MIT PF04212.16 001257451.1_29628001_2 - 0.053 13.5 8.4 0.66 10.0 0.3 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.5 001257451.1_29628001_2 - 0.21 11.7 7.6 1.7 8.8 0.5 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.4 001257451.1_29628001_2 - 0.35 10.7 12.4 5.5 6.9 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.18 001257451.1_29628001_2 - 0.49 10.6 2.0 58 4.1 0.1 3.4 3 0 0 3 3 2 0 PPR repeat TPR_21 PF09976.7 001257451.1_29628001_2 - 0.63 9.6 11.5 0.62 9.7 0.1 3.6 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain PI31_Prot_N PF11566.6 001257458.1_29625001_1 - 1.6e-15 57.1 0.0 2.7e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal F-box-like PF12937.5 001257458.1_29625001_1 - 3.2e-09 36.4 3.7 6.7e-09 35.4 3.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001257458.1_29625001_1 - 0.00022 20.9 2.6 0.00053 19.7 2.6 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.9 001257458.1_29625001_1 - 0.12 12.8 0.2 0.22 11.9 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A COMM_domain PF07258.12 001266242.1_29623001_2 - 1.8e-24 85.5 0.2 4.6e-24 84.2 0.0 1.8 2 0 0 2 2 2 1 COMM domain SpoIIIAH PF12685.5 001038659.1_29622001_1 - 0.0099 15.6 0.4 0.012 15.3 0.4 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF3439 PF11921.6 001038659.1_29622001_1 - 0.04 13.8 0.3 0.056 13.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PDE8 PF08629.8 001038659.1_29622001_1 - 0.54 10.2 5.4 0.32 10.9 2.7 2.0 2 0 0 2 2 2 0 PDE8 phosphodiesterase PWI PF01480.15 001261062.1_29629001_2 - 4.2e-08 33.3 0.1 8e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.22 001261062.1_29629001_2 - 0.00028 20.6 1.1 0.00057 19.6 1.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.20 001261062.1_29629001_2 - 0.00037 20.1 0.1 0.00079 19.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.5 001261062.1_29629001_2 - 0.0016 18.8 30.5 0.0016 18.8 30.5 2.8 4 0 0 4 4 4 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Nup35_RRM_2 PF14605.4 001261062.1_29629001_2 - 0.0056 16.5 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF342 PF03961.11 001261062.1_29629001_2 - 0.16 10.4 8.1 0.29 9.5 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CALM_bind PF16025.3 001261062.1_29629001_2 - 3.6 7.9 8.9 11 6.4 8.9 1.8 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Ig_3 PF13927.4 001039950.1_29622001_1 - 1.8e-11 44.3 0.0 0.00012 22.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 001039950.1_29622001_1 - 8.4e-11 41.9 0.0 0.00049 20.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001039950.1_29622001_1 - 2.7e-09 37.0 0.0 0.0031 17.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain FKBP_C PF00254.26 001261070.1_29624001_2 - 6.9e-15 55.0 0.0 1.1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.26 001261070.1_29624001_2 - 2.6e-12 45.9 3.7 1e-05 25.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.15 001261070.1_29624001_2 - 1.9e-11 43.1 2.8 1.5e-05 24.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.4 001261070.1_29624001_2 - 1e-08 35.1 0.6 3.5e-05 24.1 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001261070.1_29624001_2 - 1.8e-08 34.2 1.5 0.00095 19.1 0.1 2.4 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.4 001261070.1_29624001_2 - 6.5e-07 29.8 1.5 6e-05 23.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.4 001261070.1_29624001_2 - 3.8e-06 26.8 0.1 1.1e-05 25.4 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.4 001261070.1_29624001_2 - 5.6e-06 25.8 0.5 4.6e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.4 001261070.1_29624001_2 - 1.9e-05 24.4 0.9 0.0002 21.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.4 001261070.1_29624001_2 - 0.00014 21.6 0.3 0.018 14.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.4 001261070.1_29624001_2 - 0.00022 21.5 3.7 0.00032 21.0 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.4 001261070.1_29624001_2 - 0.00054 20.0 0.4 0.033 14.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.4 001261070.1_29624001_2 - 0.0012 19.0 1.9 0.0034 17.5 0.4 2.3 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001261070.1_29624001_2 - 0.0035 17.4 1.2 0.02 15.0 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.4 001261070.1_29624001_2 - 0.018 15.2 2.2 0.67 10.2 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.4 001261070.1_29624001_2 - 0.019 15.5 0.1 0.44 11.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.4 001261070.1_29624001_2 - 0.031 14.1 2.3 0.89 9.4 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat RRM_1 PF00076.20 001261071.1_29624001_2 - 7.8e-19 67.1 0.1 1.2e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001261071.1_29624001_2 - 1.3e-07 31.1 0.0 2.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coilin_N PF15862.3 001257478.1_29624001_3 - 1.5e-34 118.7 0.0 1.5e-34 118.7 0.0 3.4 2 1 0 3 3 3 1 Coilin N-terminus p450 PF00067.20 001040216.1_29623001_1 - 1.2e-151 505.5 0.7 1.3e-151 505.3 0.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 Wap1 PF16997.3 001040216.1_29623001_1 - 0.0016 17.5 0.1 0.0023 17.1 0.1 1.3 1 0 0 1 1 1 1 Wap1 domain Cyclin_N PF00134.21 001257490.1_29628001_1 - 4.8e-14 52.1 0.2 7.5e-14 51.5 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.9 001257490.1_29628001_1 - 6.4e-11 42.7 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin p450 PF00067.20 001040239.1_29624001_2 - 3e-161 537.1 0.3 3.5e-161 536.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 MH2 PF03166.12 001261090.1_29626001_2 - 4.1e-78 261.7 0.0 6.1e-78 261.2 0.0 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.14 001261090.1_29626001_2 - 1.6e-39 134.1 0.5 1.6e-39 134.1 0.5 1.8 2 0 0 2 2 2 1 MH1 domain IRF-3 PF10401.7 001261090.1_29626001_2 - 0.068 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 Glyco_transf_29 PF00777.16 001257500.1_29625001_2 - 3.9e-75 252.6 0.0 6.4e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) COX7a PF02238.13 001040278.2_29621001_1 - 5.9e-10 39.3 0.0 8.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Amidase PF01425.19 001257501.1_29624001_1 - 3.1e-127 425.2 0.0 5.1e-126 421.1 0.0 2.0 1 1 0 1 1 1 1 Amidase Golgin_A5 PF09787.7 001257502.1_29626001_3 - 3e-140 466.9 26.4 3e-140 466.9 26.4 3.3 1 1 2 3 3 3 1 Golgin subfamily A member 5 Spc7 PF08317.9 001257502.1_29626001_3 - 0.00054 18.8 85.8 0.0084 14.9 12.0 4.5 1 1 4 5 5 5 4 Spc7 kinetochore protein HIP1_clath_bdg PF16515.3 001257502.1_29626001_3 - 0.00055 20.4 15.2 0.00055 20.4 15.2 6.8 1 1 6 7 7 7 1 Clathrin-binding domain of Huntingtin-interacting protein 1 PKcGMP_CC PF16808.3 001257502.1_29626001_3 - 0.016 14.9 1.0 0.016 14.9 1.0 4.4 5 1 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Reo_sigmaC PF04582.10 001257502.1_29626001_3 - 1.5 8.0 34.7 1.1 8.5 9.3 4.3 1 1 2 4 4 4 0 Reovirus sigma C capsid protein PP28 PF10252.7 001266283.1_29623001_1 - 1.5e-29 102.1 17.2 1.5e-29 102.1 17.2 2.3 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 FH2 PF02181.21 001257504.1_29629001_1 - 1.2e-114 383.2 14.1 1.2e-114 383.2 14.1 2.7 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_FH3 PF06367.14 001257504.1_29629001_1 - 6e-61 205.3 3.5 6e-61 205.3 3.5 3.5 2 1 1 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.11 001257504.1_29629001_1 - 1.6e-54 184.2 0.9 1.6e-54 184.2 0.9 3.8 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain APG6 PF04111.10 001257504.1_29629001_1 - 1.2e-05 24.7 12.5 1.2e-05 24.7 12.5 4.9 4 1 2 6 6 6 1 Autophagy protein Apg6 Reo_sigmaC PF04582.10 001257504.1_29629001_1 - 0.57 9.4 2.8 10 5.3 0.5 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF948 PF06103.9 001257504.1_29629001_1 - 0.77 9.9 10.8 0.22 11.7 6.5 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.10 001257504.1_29629001_1 - 4.6 7.1 26.2 0.21 11.4 12.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.9 001257504.1_29629001_1 - 7.5 6.0 25.7 0.9 9.0 2.8 3.8 3 1 1 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase HemX PF04375.12 001257504.1_29629001_1 - 9 5.3 27.8 0.26 10.4 14.3 3.5 4 0 0 4 4 4 0 HemX, putative uroporphyrinogen-III C-methyltransferase TB2_DP1_HVA22 PF03134.17 001266282.1_29623001_3 - 4.1e-27 93.8 9.6 7.2e-27 93.0 9.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.7 001266282.1_29623001_3 - 0.062 13.4 2.7 0.11 12.6 2.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) PHF12_MRG_bd PF16737.3 001266285.1_29628001_1 - 1.6e-18 65.9 0.9 4.3e-18 64.6 0.9 1.8 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain PHD PF00628.27 001266285.1_29628001_1 - 1.1e-16 60.4 26.9 3.3e-09 36.4 13.3 3.5 3 0 0 3 3 3 2 PHD-finger FHA PF00498.24 001266285.1_29628001_1 - 0.00051 20.2 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain C1_1 PF00130.20 001266285.1_29628001_1 - 0.0069 16.1 16.1 0.017 14.9 1.7 3.1 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.4 001266285.1_29628001_1 - 0.12 11.8 0.1 0.12 11.8 0.1 4.7 6 0 0 6 6 6 0 PHD-finger Pkinase_Tyr PF07714.15 001257512.1_29627001_1 - 1.7e-91 306.0 0.0 2.2e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001257512.1_29627001_1 - 4.1e-44 150.8 0.0 5.5e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.22 001257512.1_29627001_1 - 1.5e-27 95.4 0.1 2.6e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.26 001257512.1_29627001_1 - 1.4e-18 66.1 0.4 3.8e-18 64.7 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.4 001257512.1_29627001_1 - 3.1e-13 49.2 0.0 6.8e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 001257512.1_29627001_1 - 6.3e-11 41.7 0.0 1.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_S3_C PF00189.18 001266290.1_29622001_1 - 2.7e-23 82.2 0.9 1e-22 80.3 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.15 001266290.1_29622001_1 - 2.1e-11 43.4 0.1 3.4e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 KH domain Rad60-SLD PF11976.6 001261108.1_29624001_2 - 1.7e-24 85.3 0.1 2.4e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.21 001261108.1_29624001_2 - 1.4e-10 40.6 0.1 2e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Ig_2 PF13895.4 001040677.1_29623001_3 - 1.9e-16 60.0 0.9 9.2e-15 54.6 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.4 001040677.1_29623001_3 - 3.9e-07 30.5 0.8 0.00021 21.7 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain FA_hydroxylase PF04116.11 001257519.1_29627001_1 - 1.4e-20 73.8 16.3 1.4e-20 73.8 16.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF202 PF02656.13 001266299.2_29622001_1 - 1.9 8.8 11.3 0.12 12.7 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3583 PF12126.6 001042434.1_29626001_1 - 2.9e-180 598.7 10.5 4.3e-180 598.2 10.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-B_box PF00643.22 001042434.1_29626001_1 - 3.9e-07 30.0 3.9 3.9e-07 30.0 3.9 3.8 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_3 PF13920.4 001042434.1_29626001_1 - 9.3e-05 22.1 10.9 9.3e-05 22.1 10.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001042434.1_29626001_1 - 0.0037 16.9 13.2 0.0037 16.9 13.2 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 001042434.1_29626001_1 - 0.005 16.6 12.5 0.005 16.6 12.5 3.3 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.23 001042434.1_29626001_1 - 0.0052 16.5 14.8 0.0052 16.5 14.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) OmpH PF03938.12 001042434.1_29626001_1 - 0.087 12.7 8.4 0.033 14.1 5.5 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1690 PF07956.9 001042434.1_29626001_1 - 0.58 10.4 3.9 0.95 9.7 2.5 2.2 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Cep57_CLD_2 PF14197.4 001042434.1_29626001_1 - 0.67 9.9 5.7 0.33 10.9 2.6 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CD20 PF04103.13 001257536.1_29622001_3 - 1.1e-24 87.1 0.3 1.7e-24 86.5 0.3 1.2 1 0 0 1 1 1 1 CD20-like family FERM_M PF00373.16 001266319.1_29627001_1 - 1.7e-47 160.5 0.0 5.1e-47 159.0 0.0 1.8 1 1 0 1 1 1 1 FERM central domain PH PF00169.27 001266319.1_29627001_1 - 1.2e-09 38.4 0.2 3.3e-09 37.1 0.2 1.7 1 0 0 1 1 1 1 PH domain FERM_N PF09379.8 001266319.1_29627001_1 - 0.0085 15.9 0.0 0.023 14.5 0.0 1.8 1 1 0 1 1 1 1 FERM N-terminal domain Serinc PF03348.13 001257550.1_29625001_3 - 1.7e-174 580.6 19.0 2.1e-174 580.4 19.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) FOXP-CC PF16159.3 001266321.1_29626001_1 - 2.4e-34 117.6 5.3 2.4e-34 117.6 5.3 4.3 3 1 0 3 3 3 1 FOXP coiled-coil domain Forkhead PF00250.16 001266321.1_29626001_1 - 3.3e-28 97.7 0.2 8.2e-28 96.4 0.2 1.7 1 0 0 1 1 1 1 Forkhead domain DUF4298 PF14131.4 001266321.1_29626001_1 - 5 7.0 16.4 4.1 7.3 13.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) Auxin_repressed PF05564.10 001266321.1_29626001_1 - 7.1 7.2 7.3 10 6.7 3.7 2.7 2 0 0 2 2 2 0 Dormancy/auxin associated protein UPF0016 PF01169.17 001266322.1_29623001_1 - 9.3e-44 147.5 19.4 4.5e-22 78.0 3.1 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Proteasome PF00227.24 001257562.1_29623001_3 - 4.9e-55 185.8 0.0 6.3e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001257562.1_29623001_3 - 1.1e-13 50.4 0.1 1.9e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sec3_C PF09763.7 001261145.1_29627001_3 - 2.3e-182 607.9 20.6 3e-182 607.6 20.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.4 001261145.1_29627001_3 - 1.6e-26 92.1 1.9 4.6e-26 90.6 1.9 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF310 PF03750.11 001261145.1_29627001_3 - 0.064 14.0 3.1 0.19 12.4 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF310) FlaC_arch PF05377.9 001261145.1_29627001_3 - 0.18 12.1 5.2 0.5 10.7 2.3 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AKNA PF12443.6 001261145.1_29627001_3 - 0.57 10.7 3.6 1 9.9 1.0 2.8 3 1 1 4 4 4 0 AT-hook-containing transcription factor DUF972 PF06156.11 001261145.1_29627001_3 - 2.7 8.5 7.2 1.5 9.4 1.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Kelch_1 PF01344.23 001266339.1_29627001_1 - 1.2e-77 255.2 19.6 2.2e-14 52.6 0.1 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.4 001266339.1_29627001_1 - 5.8e-44 146.9 13.2 1e-09 38.2 0.1 6.7 2 2 4 6 6 6 6 Kelch motif BACK PF07707.13 001266339.1_29627001_1 - 9.1e-34 115.5 0.3 1.6e-33 114.7 0.3 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.29 001266339.1_29627001_1 - 2e-31 108.4 0.6 3.7e-31 107.5 0.6 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.13 001266339.1_29627001_1 - 6.8e-28 95.4 6.6 3.1e-05 23.6 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.4 001266339.1_29627001_1 - 3.2e-27 94.1 11.5 5.4e-08 32.8 0.7 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.4 001266339.1_29627001_1 - 1.3e-22 79.3 9.0 0.0022 17.8 0.2 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.4 001266339.1_29627001_1 - 6.8e-10 38.6 10.9 0.09 12.7 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Miff PF05644.9 001261152.1_29622001_2 - 3.3e-12 46.5 6.9 6.3e-12 45.6 6.9 1.5 1 1 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff DUF1759 PF03564.13 001261152.1_29622001_2 - 0.04 13.7 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) RWD PF05773.20 001257574.1_29626001_2 - 7.4e-15 55.1 0.1 1.5e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 RWD domain AATF-Che1 PF13339.4 001257577.1_29625001_2 - 1.2e-37 129.6 0.3 1.2e-37 129.6 0.3 2.1 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.10 001257577.1_29625001_2 - 1e-26 93.1 0.5 3.5e-26 91.4 0.5 2.0 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal TPR_1 PF00515.26 001257581.1_29622001_2 - 6.2e-19 66.8 3.8 3.5e-08 32.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.15 001257581.1_29622001_2 - 8.5e-16 56.6 3.5 3.7e-08 32.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.4 001257581.1_29622001_2 - 2.3e-12 45.9 1.0 8.9e-05 22.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.4 001257581.1_29622001_2 - 1.1e-09 38.2 0.9 0.0064 17.1 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.4 001257581.1_29622001_2 - 1.8e-09 37.0 4.0 6.3e-05 22.4 0.0 4.2 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.4 001257581.1_29622001_2 - 1.7e-07 31.3 0.2 0.16 12.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.4 001257581.1_29622001_2 - 3.5e-07 30.7 2.5 0.028 15.0 0.7 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.4 001257581.1_29622001_2 - 1.6e-06 27.6 2.1 0.049 13.6 0.4 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.4 001257581.1_29622001_2 - 1.6e-06 28.0 0.5 0.033 14.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.4 001257581.1_29622001_2 - 2.4e-06 27.5 0.4 9e-05 22.4 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.4 001257581.1_29622001_2 - 6.3e-06 25.8 3.7 0.57 10.0 0.2 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.4 001257581.1_29622001_2 - 6.6e-06 26.4 3.3 0.083 13.3 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.12 001257581.1_29622001_2 - 5.2e-05 23.4 0.0 0.2 12.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.4 001257581.1_29622001_2 - 0.0034 17.8 2.2 3.1 8.5 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001257581.1_29622001_2 - 0.0078 16.1 1.8 0.13 12.3 0.1 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat DUF1936 PF09151.8 001257581.1_29622001_2 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) ANAPC3 PF12895.5 001257581.1_29622001_2 - 0.022 14.8 1.5 0.66 10.1 0.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.7 001257581.1_29622001_2 - 0.078 12.3 0.1 6.7 6.1 0.1 2.4 2 0 0 2 2 2 0 SHNi-TPR TPR_3 PF07720.10 001257581.1_29622001_2 - 0.081 12.8 2.3 0.2 11.5 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ARF7EP_C PF14949.4 001261159.1_29624001_1 - 4.5e-36 123.5 3.6 8.7e-36 122.6 3.6 1.5 1 0 0 1 1 1 1 ARF7 effector protein C-terminus DUF2039 PF10217.7 001261161.1_29622001_1 - 1.7e-31 108.2 19.3 1.7e-31 108.2 19.3 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.7 001261161.1_29622001_1 - 0.13 12.7 18.8 0.41 11.1 18.0 2.2 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.10 001261161.1_29622001_1 - 0.18 11.7 12.5 0.39 10.6 12.5 1.5 1 0 0 1 1 1 0 zinc-ribbons Mtp PF03821.14 001261172.1_29623001_3 - 1.1e-21 77.5 15.8 3.2e-15 56.3 4.8 2.3 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.3 001261172.1_29623001_3 - 0.024 15.1 4.0 0.024 15.1 4.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4728) DUF4524 PF15025.4 001266367.1_29625001_2 - 2.1e-60 202.6 0.0 4.7e-59 198.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4524) DUF4520 PF15016.4 001266367.1_29625001_2 - 5.7e-38 128.8 0.0 2.5e-35 120.3 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) ADP_ribosyl_GH PF03747.12 001261181.2_29627001_3 - 1.4e-54 185.7 2.9 1.8e-54 185.3 2.9 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase UBN_AB PF14075.4 001257606.1_29629001_2 - 4.1e-79 265.1 4.1 4.1e-79 265.1 4.1 2.6 2 1 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.8 001257606.1_29629001_2 - 8.8e-20 70.3 0.7 2.4e-19 68.9 0.7 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain PI3K_P85_iSH2 PF16454.3 001261197.1_29627001_3 - 3.7e-61 205.3 22.0 3.7e-61 205.3 22.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.22 001261197.1_29627001_3 - 9.9e-41 137.6 0.2 4e-20 71.5 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.25 001261197.1_29627001_3 - 6e-31 107.2 0.5 6e-31 107.2 0.5 2.1 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.26 001261197.1_29627001_3 - 1.3e-05 24.5 0.9 0.00073 19.0 0.0 2.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.15 001261197.1_29627001_3 - 0.00013 21.4 0.0 0.00034 20.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 001261197.1_29627001_3 - 0.00034 20.3 0.1 0.0008 19.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Laminin_I PF06008.12 001261197.1_29627001_3 - 0.006 16.2 10.0 0.011 15.3 10.0 1.3 1 0 0 1 1 1 1 Laminin Domain I Lant_dehydr_C PF14028.4 001261197.1_29627001_3 - 0.0092 15.4 0.7 0.015 14.7 0.7 1.2 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term Mod_r PF07200.11 001261197.1_29627001_3 - 0.058 13.4 19.5 0.53 10.2 2.8 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.12 001261197.1_29627001_3 - 0.23 11.1 17.5 0.95 9.1 17.2 2.1 1 1 0 1 1 1 0 IncA protein Transcrip_act PF04949.11 001261197.1_29627001_3 - 1.8 8.3 13.9 0.64 9.8 5.8 2.7 1 1 1 2 2 2 0 Transcriptional activator Exonuc_VII_L PF02601.13 001261197.1_29627001_3 - 2.8 7.3 8.1 5.2 6.4 8.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.4 001261197.1_29627001_3 - 3.2 6.9 7.8 5.3 6.2 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.9 001261197.1_29627001_3 - 4.9 7.2 14.7 0.24 11.4 3.4 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.20 001261197.1_29627001_3 - 8.7 6.5 12.1 4 7.6 4.2 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.7 001261197.1_29627001_3 - 9.8 6.8 10.1 2.4 8.8 1.2 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Arf PF00025.19 001266393.1_29625001_3 - 2.8e-37 127.7 0.0 4.4e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.18 001266393.1_29625001_3 - 3.4e-05 23.0 0.1 0.0056 15.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.21 001266393.1_29625001_3 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.11 001266393.1_29625001_3 - 0.00024 21.2 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 001266393.1_29625001_3 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.8 001266393.1_29625001_3 - 0.0019 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001266393.1_29625001_3 - 0.0053 16.0 0.1 0.013 14.8 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.25 001266393.1_29625001_3 - 0.0053 17.1 0.0 0.0081 16.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.14 001266393.1_29625001_3 - 0.063 13.0 0.0 0.9 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RsfS PF02410.13 001261201.2_29622001_2 - 6.8e-26 90.4 0.0 9e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SNURF PF07192.9 001261205.1_29623001_1 - 6.2e-45 150.7 6.1 1e-44 150.0 6.1 1.4 1 0 0 1 1 1 1 SNURF/RPN4 protein LSM PF01423.20 001261205.1_29623001_3 - 1.1e-19 69.7 0.1 1.5e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain zf-H2C2_2 PF13465.4 001257633.1_29625001_3 - 1.2e-39 132.9 83.8 1.9e-07 31.1 2.6 11.5 11 1 0 11 11 11 8 Zinc-finger double domain zf-H2C2_5 PF13909.4 001257633.1_29625001_3 - 5.6e-38 128.2 72.5 5e-08 32.4 3.6 10.3 10 0 0 10 10 10 9 C2H2-type zinc-finger domain zf-C2H2 PF00096.24 001257633.1_29625001_3 - 5.2e-32 108.4 90.1 0.00038 20.6 3.6 11.2 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001257633.1_29625001_3 - 5.7e-20 70.2 87.6 0.0089 16.6 1.6 11.5 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001257633.1_29625001_3 - 5.2e-09 35.7 1.1 5.2e-09 35.7 1.1 10.3 13 0 0 13 13 13 3 C2H2-type zinc finger zf-met PF12874.5 001257633.1_29625001_3 - 7e-06 26.1 8.1 0.00048 20.3 0.4 9.8 11 1 0 11 11 11 6 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 001257633.1_29625001_3 - 0.01 15.4 0.1 0.01 15.4 0.1 7.6 8 0 0 8 8 8 0 zinc-finger C2H2-type Peptidase_C74 PF12387.6 001257633.1_29625001_3 - 1.7 8.0 3.7 3.6 6.9 3.7 1.5 1 0 0 1 1 1 0 Pestivirus NS2 peptidase zf-C2H2_2 PF12756.5 001257633.1_29625001_3 - 2 8.7 58.8 2 8.7 7.3 8.0 2 1 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.6 001257633.1_29625001_3 - 3.2 8.1 59.2 0.75 10.1 0.1 10.2 11 0 0 11 11 11 0 Zinc-finger double-stranded RNA-binding Kelch_4 PF13418.4 001266406.1_29626001_3 - 1.1e-27 95.6 0.5 1.3e-07 31.3 0.1 5.7 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.4 001266406.1_29626001_3 - 3e-24 84.6 9.3 1.7e-08 34.4 0.1 5.9 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.4 001266406.1_29626001_3 - 5.6e-21 74.0 6.1 6.8e-08 32.2 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.23 001266406.1_29626001_3 - 5.7e-18 64.1 0.4 1.3e-06 27.8 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.13 001266406.1_29626001_3 - 8.8e-18 63.4 10.5 1.3e-08 34.3 0.4 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.4 001266406.1_29626001_3 - 1.8e-16 59.6 8.0 0.00014 21.9 0.1 5.5 4 1 1 5 5 5 3 Kelch motif F-box-like PF12937.5 001266406.1_29626001_3 - 2.2e-09 36.9 0.0 6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001266406.1_29626001_3 - 2.8e-07 30.1 0.0 5.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain PX PF00787.22 001266411.1_29623001_1 - 2.9e-15 56.1 1.9 5.3e-15 55.3 1.3 1.6 1 1 1 2 2 2 1 PX domain Spot_14 PF07084.10 001257645.1_29625001_2 - 1.1e-63 213.8 0.0 1.4e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 RINGv PF12906.5 001266413.1_29623001_2 - 4.5e-15 55.4 9.8 1e-14 54.2 9.8 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.4 001266413.1_29623001_2 - 0.0086 16.2 9.9 0.0086 16.2 9.9 2.6 2 0 0 2 2 2 1 Ring finger domain Baculo_IE-1 PF05290.9 001266413.1_29623001_2 - 0.022 14.6 0.7 0.04 13.7 0.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Vpu PF00558.17 001266413.1_29623001_2 - 0.13 11.9 0.2 0.23 11.1 0.2 1.3 1 0 0 1 1 1 0 Vpu protein DEAD PF00270.27 001266416.1_29624001_2 - 1.7e-42 145.1 0.2 2.6e-42 144.4 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001266416.1_29624001_2 - 9e-32 109.6 0.0 3.5e-31 107.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001266416.1_29624001_2 - 0.00026 20.9 0.0 0.00052 19.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.4 001266416.1_29624001_2 - 0.00038 20.1 0.0 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.4 001266416.1_29624001_2 - 0.00047 20.4 0.0 0.0041 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain UTP25 PF06862.10 001266416.1_29624001_2 - 0.012 14.3 0.0 1.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.4 001266416.1_29624001_2 - 0.092 12.9 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Tropomodulin PF03250.12 001266419.1_29623001_2 - 1.5e-61 206.4 4.1 3e-61 205.5 4.1 1.5 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.4 001266419.1_29623001_2 - 0.019 14.9 0.3 0.09 12.8 0.1 2.3 2 0 0 2 2 2 0 Leucine Rich repeat HDC PF02329.14 001266419.1_29623001_2 - 0.071 12.0 0.0 0.2 10.5 0.0 1.7 1 1 1 2 2 2 0 Histidine carboxylase PI chain Usher PF00577.18 001266419.1_29623001_2 - 0.079 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Outer membrane usher protein PAP2_C PF14360.4 001257652.1_29628001_1 - 7.1e-28 96.8 14.6 3.1e-27 94.7 14.6 2.2 1 0 0 1 1 1 1 PAP2 superfamily C-terminal PAP2 PF01569.19 001257652.1_29628001_1 - 4.8e-07 29.5 6.7 1.1e-06 28.4 6.7 1.6 1 0 0 1 1 1 1 PAP2 superfamily SAM_1 PF00536.28 001257652.1_29628001_1 - 0.00035 20.8 0.0 0.00068 19.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2_3 PF14378.4 001257652.1_29628001_1 - 0.00077 19.1 11.1 0.00077 19.1 11.1 1.9 1 1 1 2 2 2 1 PAP2 superfamily SAM_2 PF07647.15 001257652.1_29628001_1 - 0.037 14.0 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.14 001257652.1_29628001_1 - 0.068 13.0 0.1 0.23 11.3 0.1 1.9 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Erv26 PF04148.11 001261231.1_29627001_2 - 7.3e-54 182.6 16.2 1.5e-53 181.6 16.2 1.5 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 MIF PF01187.16 001257668.1_29622001_1 - 1e-50 170.6 0.0 1.3e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Antirestrict PF03230.11 001257668.1_29622001_2 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Antirestriction protein UPF0220 PF05255.9 001261245.1_29625001_1 - 4e-45 153.2 4.8 6.4e-45 152.5 4.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Sec10 PF07393.9 001261248.2_29627001_2 - 1.4e-153 512.9 28.5 5.2e-152 507.7 21.5 3.3 2 1 0 2 2 2 1 Exocyst complex component Sec10 Jnk-SapK_ap_N PF09744.7 001261248.2_29627001_2 - 0.0027 17.8 4.7 0.0027 17.8 4.7 2.6 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 OmpH PF03938.12 001261248.2_29627001_2 - 0.47 10.3 15.0 0.92 9.4 13.9 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Phasin PF05597.9 001261248.2_29627001_2 - 3.5 7.5 8.3 1.3 8.9 0.9 3.4 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TelA PF05816.9 001261248.2_29627001_2 - 6.5 5.6 18.8 0.3 10.0 4.9 3.3 3 1 0 3 3 3 0 Toxic anion resistance protein (TelA) His_Phos_2 PF00328.20 001257685.2_29624001_1 - 1.7e-21 76.9 0.0 1.8e-20 73.5 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NUDIX PF00293.26 001261255.1_29625001_3 - 6.2e-18 65.0 0.5 9.4e-18 64.4 0.5 1.2 1 0 0 1 1 1 1 NUDIX domain Amelogenin PF02948.13 001098513.1_29622001_1 - 1.5e-63 214.4 61.2 1e-62 211.7 61.2 1.8 1 1 0 1 1 1 1 Amelogenin TFIIA PF03153.11 001098513.1_29622001_1 - 3 7.6 6.2 2.9 7.6 6.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ig_3 PF13927.4 001266463.2_29624001_1 - 5.6e-25 87.6 4.9 1.9e-13 50.7 0.4 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001266463.2_29624001_1 - 1.6e-20 72.9 1.3 1.6e-09 37.7 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001266463.2_29624001_1 - 3.6e-18 65.3 0.0 1.9e-08 34.2 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.4 001266463.2_29624001_1 - 2.8e-16 59.5 3.5 2.8e-08 33.9 0.1 2.4 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001266463.2_29624001_1 - 5.8e-14 52.0 3.5 1.2e-09 38.1 0.1 3.0 3 1 0 3 3 3 2 Immunoglobulin V-set domain C1-set PF07654.13 001266463.2_29624001_1 - 3.1e-08 33.9 0.2 0.0028 18.0 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin C1-set domain C2-set_2 PF08205.10 001266463.2_29624001_1 - 0.00061 19.7 0.5 0.017 15.1 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.13 001266463.2_29624001_1 - 0.018 14.7 0.3 0.038 13.6 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 V-set_CD47 PF08204.9 001266463.2_29624001_1 - 0.03 14.2 0.1 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Ig_4 PF16680.3 001266463.2_29624001_1 - 0.13 12.5 0.8 23 5.3 0.0 2.7 3 1 0 3 3 2 0 T-cell surface glycoprotein CD3 delta chain FixQ PF05545.9 001266463.2_29624001_1 - 0.47 10.3 1.7 28 4.6 0.5 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DCP2 PF05026.11 001266464.1_29626001_1 - 1.9e-29 101.7 0.1 4e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.26 001266464.1_29626001_1 - 2.2e-15 56.7 0.0 3.6e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FYTT PF07078.9 001266475.1_29623001_1 - 4.7e-169 561.4 18.7 5.4e-169 561.2 18.7 1.0 1 0 0 1 1 1 1 Forty-two-three protein Presenilin PF01080.15 001266480.1_29628001_1 - 8.2e-165 548.2 9.1 8.2e-165 548.2 9.1 1.8 2 0 0 2 2 2 1 Presenilin CBFD_NFYB_HMF PF00808.21 001257720.1_29626001_3 - 3.8e-28 97.4 0.6 6.3e-28 96.7 0.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.22 001257720.1_29626001_3 - 0.00015 22.0 0.0 0.00025 21.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.14 001257720.1_29626001_3 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.4 001257720.1_29626001_3 - 0.021 14.8 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold GMP_PDE_delta PF05351.9 001266482.1_29629001_3 - 3.7e-73 244.6 0.6 4.8e-73 244.3 0.6 1.2 1 0 0 1 1 1 1 GMP-PDE, delta subunit 2-oxoacid_dh PF00198.21 001261277.1_29624001_2 - 6.2e-80 267.9 0.0 8.9e-80 267.3 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.20 001261277.1_29624001_2 - 1.4e-20 72.7 0.1 3e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.15 001261277.1_29624001_2 - 7.3e-16 58.1 0.1 1.4e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.4 001261277.1_29624001_2 - 0.0086 15.8 0.1 2.9 7.7 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.3 001261277.1_29624001_2 - 0.067 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Toprim_Crpt PF13342.4 001261277.1_29624001_2 - 0.14 12.1 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase zf-C3HC4_3 PF13920.4 001266485.1_29624001_2 - 1.6e-09 37.4 10.6 3.8e-09 36.1 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001266485.1_29624001_2 - 1e-08 35.1 14.4 1e-08 35.1 14.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.4 001266485.1_29624001_2 - 1.2e-08 34.5 13.6 3.5e-08 33.0 13.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001266485.1_29624001_2 - 9.4e-06 25.3 13.2 9.4e-06 25.3 13.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001266485.1_29624001_2 - 1.5e-05 24.7 10.8 4.8e-05 23.0 10.8 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 001266485.1_29624001_2 - 3.7e-05 23.5 10.8 0.00012 21.8 10.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.5 001266485.1_29624001_2 - 0.00018 21.6 9.5 0.00018 21.6 9.5 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.4 001266485.1_29624001_2 - 0.00093 19.0 14.6 0.0058 16.4 14.0 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.4 001266485.1_29624001_2 - 0.018 15.0 9.4 0.071 13.1 9.4 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING GCV_T PF01571.19 001266500.1_29627001_1 - 2.2e-84 282.7 0.0 2.7e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.9 001266500.1_29627001_1 - 4.3e-22 78.0 0.0 7.4e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Cementoin PF10511.7 001110511.1_29622001_3 - 2.3e-15 55.6 14.4 8.5e-08 31.7 0.3 3.6 1 1 1 3 3 3 3 Trappin protein transglutaminase binding domain WAP PF00095.19 001110511.1_29622001_3 - 2.3e-09 37.3 12.7 2.3e-09 37.3 12.7 1.8 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Chorion_1 PF01723.14 001110511.1_29622001_3 - 0.0082 16.0 0.2 0.012 15.5 0.2 1.2 1 0 0 1 1 1 1 Chorion protein Cpn60_TCP1 PF00118.22 001266509.2_29626001_3 - 2.2e-121 405.8 0.0 2.5e-121 405.6 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2781 PF10914.6 001257751.2_29622001_3 - 1.2e-46 158.6 8.2 1.6e-46 158.2 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Syntaxin-6_N PF09177.9 001261300.1_29625001_3 - 5.8e-38 129.3 0.9 5.8e-38 129.3 0.9 2.3 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.17 001261300.1_29625001_3 - 4.7e-11 42.4 0.7 4.7e-11 42.4 0.7 1.8 2 0 0 2 2 2 1 SNARE domain FliD_C PF07195.10 001261300.1_29625001_3 - 0.0042 16.4 1.7 0.1 11.9 0.0 2.3 2 1 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Prominin PF05478.9 001261300.1_29625001_3 - 0.77 7.5 5.0 1.7 6.3 3.4 1.6 1 1 1 2 2 2 0 Prominin TBPIP PF07106.11 001261300.1_29625001_3 - 8.3 6.0 9.2 0.59 9.8 0.9 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.10 001261300.1_29625001_3 - 9.6 6.1 7.6 39 4.1 2.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1751 PF08551.8 001266515.1_29625001_2 - 1.4e-28 99.2 4.0 2.8e-28 98.2 4.0 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DUF4305 PF14146.4 001266515.1_29625001_2 - 1.1 9.4 5.1 2.6 8.2 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4305) WD40 PF00400.30 001261308.1_29629001_2 - 8.3e-37 124.4 17.9 1.8e-06 28.4 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.6 001261308.1_29629001_2 - 3.1e-25 87.6 2.0 6.2e-25 86.7 2.0 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.5 001261308.1_29629001_2 - 2.3e-09 37.3 2.4 0.026 14.7 0.1 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.5 001261308.1_29629001_2 - 7e-09 35.3 0.1 7e-09 35.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.31 001261308.1_29629001_2 - 5.1e-06 26.1 0.6 1.4e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.3 001261308.1_29629001_2 - 2.1e-05 23.9 0.2 0.021 14.0 0.4 2.3 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.6 001261308.1_29629001_2 - 0.001 17.6 8.4 0.21 10.0 0.1 4.0 3 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF5046 PF16465.3 001261308.1_29629001_2 - 0.15 11.4 0.3 2.3 7.5 0.3 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) zf-H2C2_2 PF13465.4 001261310.1_29626001_1 - 6e-65 212.8 46.1 2e-08 34.2 0.4 10.5 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.24 001261310.1_29626001_1 - 1.1e-58 192.4 59.3 3.8e-07 30.1 0.6 9.5 9 0 0 9 9 9 9 Zinc finger, C2H2 type SCAN PF02023.15 001261310.1_29626001_1 - 1e-41 140.5 5.7 2.1e-41 139.5 5.7 1.6 1 0 0 1 1 1 1 SCAN domain zf-C2H2_4 PF13894.4 001261310.1_29626001_1 - 1.4e-28 97.0 57.2 0.0018 18.8 0.6 9.7 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001261310.1_29626001_1 - 1.6e-18 66.1 48.7 0.0035 17.1 0.2 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001261310.1_29626001_1 - 8.5e-14 51.3 41.1 0.0027 17.7 3.5 6.4 3 2 5 8 8 8 7 Zinc ribbon domain XPA_N PF01286.16 001261310.1_29626001_1 - 2.7e-11 43.1 30.9 0.73 9.8 0.6 9.3 9 0 0 9 9 9 5 XPA protein N-terminal zf-C2H2_11 PF16622.3 001261310.1_29626001_1 - 5.9e-07 29.0 42.7 0.55 9.9 0.1 9.2 9 0 0 9 9 9 5 zinc-finger C2H2-type zf-C2H2_jaz PF12171.6 001261310.1_29626001_1 - 0.00013 22.0 34.5 0.09 13.0 0.1 8.3 9 0 0 9 9 9 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.3 001261310.1_29626001_1 - 0.00013 22.5 41.1 0.18 12.4 1.3 5.5 2 1 5 7 7 6 6 zinc-ribbon family C1_4 PF07975.10 001261310.1_29626001_1 - 0.0041 17.2 34.8 0.26 11.5 1.1 6.0 2 1 3 6 6 6 3 TFIIH C1-like domain CpXC PF14353.4 001261310.1_29626001_1 - 0.039 13.8 27.4 11 6.0 0.1 8.4 1 1 4 8 8 8 0 CpXC protein HypA PF01155.17 001261310.1_29626001_1 - 0.042 13.7 32.7 1.7 8.6 1.2 5.3 1 1 5 6 6 6 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ZZ PF00569.15 001261310.1_29626001_1 - 0.048 13.4 36.7 8 6.2 0.1 9.2 9 0 0 9 9 9 0 Zinc finger, ZZ type GATA PF00320.25 001261310.1_29626001_1 - 0.061 12.8 30.0 2.8 7.5 3.2 7.9 7 2 2 9 9 9 0 GATA zinc finger DUF3268 PF11672.6 001261310.1_29626001_1 - 0.072 13.3 26.8 1.1 9.5 1.5 5.2 4 1 2 6 6 6 0 zinc-finger-containing domain TFIIS_C PF01096.16 001261310.1_29626001_1 - 0.18 11.5 40.3 14 5.5 0.1 9.3 9 0 0 9 9 9 0 Transcription factor S-II (TFIIS) YhfH PF14149.4 001261310.1_29626001_1 - 0.53 10.2 35.6 14 5.6 0.1 9.1 9 0 0 9 9 9 0 YhfH-like protein zf-AN1 PF01428.14 001261310.1_29626001_1 - 0.77 9.8 39.5 20 5.3 1.5 9.2 9 0 0 9 9 9 0 AN1-like Zinc finger BolA PF01722.16 001261310.1_29626001_1 - 0.97 9.6 12.1 17 5.7 0.1 4.9 4 1 0 5 5 5 0 BolA-like protein ADK_lid PF05191.12 001261310.1_29626001_1 - 1.6 8.7 23.2 5.6 6.9 0.3 6.1 3 2 3 6 6 6 0 Adenylate kinase, active site lid zf-LYAR PF08790.9 001261310.1_29626001_1 - 4.1 7.3 29.1 26 4.7 0.1 8.7 9 0 0 9 9 9 0 LYAR-type C2HC zinc finger zinc_ribbon_4 PF13717.4 001261310.1_29626001_1 - 7.2 6.5 41.8 1.2 9.0 1.1 8.5 7 2 1 8 8 8 0 zinc-ribbon domain PBP1_TM PF14812.4 001266526.1_29622001_3 - 0.04 14.2 3.2 0.068 13.5 3.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPAR_LY6 PF00021.19 001266526.1_29622001_3 - 0.043 14.4 18.7 0.077 13.6 18.7 1.4 1 0 0 1 1 1 0 u-PAR/Ly-6 domain CENP-B_dimeris PF09026.8 001266526.1_29622001_3 - 0.34 11.2 9.4 0.54 10.5 9.4 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4366 PF14283.4 001266526.1_29622001_3 - 0.34 10.2 2.8 0.66 9.3 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DNA_pol_phi PF04931.11 001266526.1_29622001_3 - 0.46 8.4 6.1 0.63 8.0 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Dickkopf_N PF04706.10 001266526.1_29622001_3 - 1.4 9.3 10.5 1.3 9.4 1.7 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region UPAR_LY6_2 PF16975.3 001266526.1_29622001_3 - 2.3 8.3 12.6 5.2 7.2 12.6 1.5 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Arm PF00514.21 001261315.1_29626001_2 - 0.00025 20.8 0.0 0.00053 19.8 0.0 1.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HMA PF00403.24 001261315.1_29626001_2 - 0.0071 16.6 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain SET PF00856.26 001261327.1_29626001_3 - 8.7e-25 87.9 0.2 1.6e-24 87.1 0.2 1.4 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.14 001261327.1_29626001_3 - 1.7e-17 63.8 1.4 1.7e-17 63.8 1.4 3.2 4 0 0 4 4 4 1 Pre-SET motif Chromo PF00385.22 001261327.1_29626001_3 - 1e-12 47.6 2.1 2.1e-12 46.6 2.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SH2 PF00017.22 001266541.1_29625001_1 - 4.4e-13 49.0 0.1 8e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SAM_2 PF07647.15 001266541.1_29625001_1 - 7.9e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SDA1 PF05285.10 001266541.1_29625001_1 - 0.093 12.0 1.6 0.14 11.4 1.6 1.3 1 0 0 1 1 1 0 SDA1 SAM_1 PF00536.28 001266541.1_29625001_1 - 0.098 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DSPc PF00782.18 001257792.1_29626001_1 - 1.6e-42 144.3 0.0 2.3e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.18 001257792.1_29626001_1 - 2.2e-13 50.5 0.0 3.5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase PF00102.25 001257792.1_29626001_1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.10 001257792.1_29626001_1 - 0.052 13.7 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Palm_thioest PF02089.13 001261332.1_29625001_1 - 1.6e-178 591.6 0.0 2e-178 591.3 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase FKBP_C PF00254.26 001261339.1_29625001_3 - 1.8e-46 156.3 0.0 6.2e-30 103.2 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.26 001261339.1_29625001_3 - 3.7e-19 67.5 7.3 3.4e-07 29.7 0.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.15 001261339.1_29625001_3 - 9.2e-16 56.5 6.6 3e-06 26.8 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.4 001261339.1_29625001_3 - 2.2e-10 39.8 5.6 0.0011 18.9 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.4 001261339.1_29625001_3 - 3.6e-08 33.4 3.2 0.00098 19.2 1.5 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.4 001261339.1_29625001_3 - 1.2e-07 31.1 4.3 0.0078 15.7 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_6 PF13174.4 001261339.1_29625001_3 - 5.7e-07 29.6 4.5 0.0017 18.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.4 001261339.1_29625001_3 - 1.3e-06 28.8 1.5 0.12 12.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.4 001261339.1_29625001_3 - 2e-06 28.1 3.8 0.02 15.3 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.4 001261339.1_29625001_3 - 1.9e-05 24.9 0.2 0.015 15.9 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.4 001261339.1_29625001_3 - 0.00022 21.2 0.4 0.0029 17.6 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.4 001261339.1_29625001_3 - 0.00035 20.3 1.6 0.41 10.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat PknG_TPR PF16918.3 001261339.1_29625001_3 - 0.002 16.8 0.8 0.003 16.2 0.8 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_17 PF13431.4 001261339.1_29625001_3 - 0.0044 17.2 3.6 0.42 11.0 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat OmpH PF03938.12 001261339.1_29625001_3 - 0.0052 16.7 6.0 0.011 15.7 6.0 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF3856 PF12968.5 001261339.1_29625001_3 - 0.069 13.1 0.6 0.16 11.9 0.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.5 001261339.1_29625001_3 - 0.4 10.8 8.3 4.5 7.4 0.8 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.4 001261339.1_29625001_3 - 1.2 9.2 6.6 4 7.4 0.1 2.8 2 1 1 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat zf-A20 PF01754.14 001261344.1_29629001_3 - 8.3e-34 115.0 76.5 3.6e-07 29.9 8.4 8.0 7 0 0 7 7 7 7 A20-like zinc finger OTU PF02338.17 001261344.1_29629001_3 - 8.4e-33 113.4 0.0 1.8e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease ACBP PF00887.17 001261348.2_29623001_1 - 5.2e-24 84.1 0.2 7.9e-24 83.6 0.2 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.4 001261348.2_29623001_1 - 5.9e-21 74.1 2.0 3.5e-11 43.0 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.4 001261348.2_29623001_1 - 8.7e-17 61.1 2.2 2.2e-14 53.5 0.5 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001261348.2_29623001_1 - 3e-16 59.6 0.2 4.9e-16 58.9 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.28 001261348.2_29623001_1 - 5.2e-15 55.0 0.1 3.2e-06 27.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.4 001261348.2_29623001_1 - 1.6e-11 43.2 0.8 0.00041 20.5 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Glycos_transf_2 PF00535.24 001261355.1_29625001_1 - 5e-29 101.1 0.0 7.7e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.20 001261355.1_29625001_1 - 5.2e-22 78.3 1.8 9.2e-22 77.5 1.8 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.4 001261355.1_29625001_1 - 1.8e-05 24.6 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.12 001261355.1_29625001_1 - 0.0012 18.3 0.0 0.0039 16.7 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.7 001261355.1_29625001_1 - 0.0031 16.9 0.0 0.0055 16.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 SNARE_assoc PF09335.9 001257828.1_29623001_1 - 7e-20 71.6 8.4 7.7e-20 71.4 6.0 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein ThiW PF09512.8 001257828.1_29623001_1 - 0.015 15.2 2.5 0.018 15.0 0.1 2.1 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) UCH PF00443.27 001257829.1_29628001_3 - 1.2e-39 136.3 0.0 1.5e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 001257829.1_29628001_3 - 2.9e-11 43.4 0.0 7.5e-11 42.1 0.0 1.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase LSM PF01423.20 001261364.1_29622001_3 - 1.4e-19 69.4 0.2 2.2e-19 68.8 0.2 1.3 1 0 0 1 1 1 1 LSM domain CHCH PF06747.11 001257834.1_29623001_2 - 2.6e-07 30.5 8.7 4.3e-07 29.8 8.7 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.8 001257834.1_29623001_2 - 0.019 14.8 1.8 0.029 14.3 1.8 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.11 001257834.1_29623001_2 - 0.048 13.3 1.5 0.076 12.6 1.5 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MMR_HSR1_Xtn PF16897.3 001257836.1_29624001_3 - 3e-46 155.7 0.1 5e-46 155.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.19 001257836.1_29624001_3 - 4e-24 84.3 0.0 6.8e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.21 001257836.1_29624001_3 - 2e-19 69.6 0.0 3.7e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.16 001257836.1_29624001_3 - 1.4e-09 37.5 0.0 2.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.21 001257836.1_29624001_3 - 0.063 13.2 0.3 2.7 7.9 0.0 2.3 1 1 0 2 2 2 0 Dynamin family MHC_I PF00129.16 001134230.2_29624001_1 - 3.6e-94 313.2 2.2 5.1e-94 312.7 2.2 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001134230.2_29624001_1 - 6.1e-17 61.8 0.1 1.6e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001134230.2_29624001_1 - 2.9e-12 46.1 9.1 5.3e-12 45.3 9.1 1.4 1 0 0 1 1 1 1 MHC_I C-terminus C2-set_2 PF08205.10 001134230.2_29624001_1 - 0.00052 19.9 1.7 0.00068 19.5 0.1 2.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001134230.2_29624001_1 - 0.0024 17.9 0.0 0.0061 16.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain MHC_II_alpha PF00993.18 001134295.1_29622001_1 - 9.6e-36 121.2 0.0 1.3e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001134295.1_29622001_1 - 1.8e-28 97.5 0.6 3.8e-28 96.5 0.6 1.6 1 0 0 1 1 1 1 C1-set C-terminal domain C1-set PF07654.13 001134295.1_29622001_1 - 3.3e-25 88.2 0.0 5.3e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Marek_A PF02124.13 001134295.1_29622001_1 - 6e-05 22.8 0.0 8.6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Marek's disease glycoprotein A Ig_3 PF13927.4 001134295.1_29622001_1 - 0.00015 22.2 0.0 0.00024 21.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001134295.1_29622001_1 - 0.00015 21.7 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 001134295.1_29622001_1 - 0.053 13.7 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain zf-CCCH PF00642.22 001257840.2_29628001_2 - 2.6e-07 30.3 24.2 2.2e-05 24.1 2.3 4.0 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.6 001257840.2_29628001_2 - 0.0015 18.6 8.3 0.0031 17.6 6.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding TPR_2 PF07719.15 001257840.2_29628001_2 - 0.0062 16.4 0.4 2.3 8.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-met PF12874.5 001257840.2_29628001_2 - 0.085 13.1 6.5 0.14 12.4 5.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TPR_1 PF00515.26 001257840.2_29628001_2 - 0.73 9.6 3.1 8.3 6.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DOR PF14839.4 001266580.2_29625001_3 - 2.5e-86 289.6 7.9 3.4e-86 289.1 7.9 1.2 1 0 0 1 1 1 1 DOR family Ets PF00178.20 001266585.1_29626001_3 - 3.1e-33 114.0 0.3 5.8e-33 113.1 0.3 1.5 1 0 0 1 1 1 1 Ets-domain GABP-alpha PF11620.6 001266585.1_29626001_3 - 2.7e-30 104.3 0.6 5.1e-30 103.4 0.6 1.5 1 0 0 1 1 1 1 GA-binding protein alpha chain SAM_PNT PF02198.14 001266585.1_29626001_3 - 3.6e-29 100.4 0.2 7.3e-29 99.5 0.2 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Peptidase_C12 PF01088.19 001261378.2_29628001_3 - 6.8e-69 231.7 0.0 1.2e-68 230.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Nucleo_P87 PF07267.9 001261378.2_29628001_3 - 4.4 5.9 5.0 7.4 5.2 5.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BTB PF00651.29 001257854.1_29625001_1 - 1.9e-20 73.0 2.0 1.9e-20 73.0 2.0 2.3 3 0 0 3 3 3 1 BTB/POZ domain zf-C2H2 PF00096.24 001257854.1_29625001_1 - 2.6e-12 46.3 34.1 4.4e-05 23.6 1.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001257854.1_29625001_1 - 3.1e-12 46.2 22.4 6.5e-08 32.5 0.1 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 001257854.1_29625001_1 - 2.7e-10 40.1 32.6 0.0021 18.6 0.7 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.5 001257854.1_29625001_1 - 0.00036 20.7 24.1 0.0028 17.9 0.8 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 001257854.1_29625001_1 - 0.047 13.3 0.5 0.047 13.3 0.5 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.5 001257854.1_29625001_1 - 0.48 10.6 19.6 0.78 10.0 6.9 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.17 001257854.1_29625001_1 - 1.1 9.5 8.7 5.4 7.3 8.7 2.3 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_jaz PF12171.6 001257854.1_29625001_1 - 1.6 9.0 22.3 3.9 7.8 4.4 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.4 001257854.1_29625001_1 - 1.8 8.3 25.4 1.2 8.8 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.3 001257854.1_29625001_1 - 1.8 8.7 14.3 0.67 10.2 4.8 2.9 1 1 3 4 4 4 0 C2H2-type zinc ribbon RNase_H PF00075.22 001257858.1_29624001_3 - 1.8e-43 148.0 0.0 2.8e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001257858.1_29624001_3 - 6.2e-19 67.9 0.9 1.2e-18 67.0 0.9 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001257858.1_29624001_3 - 0.0059 16.2 0.0 0.012 15.2 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase-like Med23 PF11573.6 001261479.2_29629001_2 - 0 2049.2 6.2 0 2049.0 6.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Sulfotransfer_2 PF03567.12 001257866.1_29624001_3 - 4.4e-50 170.8 0.1 5.5e-50 170.5 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF1075 PF06388.9 001257866.1_29624001_3 - 0.032 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) Glycos_transf_2 PF00535.24 001257868.1_29623001_1 - 3.3e-25 88.7 0.0 4.3e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.4 001257868.1_29623001_1 - 1.1e-07 31.9 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.7 001257868.1_29623001_1 - 0.00091 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Mago-bind PF09282.8 001257874.1_29623001_2 - 1.2e-13 50.5 1.8 2.1e-13 49.7 1.8 1.4 1 0 0 1 1 1 1 Mago binding Nif11 PF07862.9 001257874.1_29623001_2 - 0.36 11.0 2.0 0.63 10.2 2.0 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function Ribosomal_60s PF00428.17 001257874.1_29623001_2 - 1.3 9.5 4.9 2.6 8.6 4.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Relaxase PF03432.12 001257874.1_29623001_2 - 3.4 7.1 6.0 4.9 6.6 6.0 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain MHC_I_3 PF16497.3 001145533.1_29622001_1 - 1.4e-74 249.8 0.1 1.8e-74 249.4 0.1 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.13 001145533.1_29622001_1 - 5.3e-13 49.1 0.0 5.3e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001145533.1_29622001_1 - 0.0028 18.1 0.1 0.015 15.8 0.1 2.1 1 1 1 2 2 2 1 Immunoglobulin domain MHC_I PF00129.16 001145533.1_29622001_1 - 0.0047 16.4 0.0 0.0088 15.5 0.0 1.6 1 1 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Kelch_3 PF13415.4 001145533.1_29622001_1 - 0.095 12.9 0.6 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain zf-H2C2_2 PF13465.4 001266619.2_29624001_3 - 2.9e-67 220.1 64.4 3.5e-10 39.7 2.4 11.8 11 0 0 11 11 11 8 Zinc-finger double domain zf-C2H2 PF00096.24 001266619.2_29624001_3 - 6.6e-46 152.1 86.1 1e-06 28.7 0.6 12.4 12 1 0 12 12 12 8 Zinc finger, C2H2 type KRAB PF01352.25 001266619.2_29624001_3 - 8.3e-26 89.3 0.3 1.3e-25 88.6 0.3 1.3 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001266619.2_29624001_3 - 2.1e-24 83.9 80.2 0.0011 19.4 3.8 12.3 12 1 0 12 12 12 8 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001266619.2_29624001_3 - 4.7e-21 74.1 59.1 1.2e-05 25.0 0.5 10.0 9 1 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001266619.2_29624001_3 - 3.7e-13 49.3 44.7 0.01 16.0 0.4 10.1 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001266619.2_29624001_3 - 1.6e-07 30.8 37.3 0.041 13.5 0.0 9.8 9 1 0 9 9 9 3 zinc-finger C2H2-type XPA_N PF01286.16 001266619.2_29624001_3 - 0.00026 20.8 38.4 2 8.4 0.2 9.0 9 0 0 9 9 9 4 XPA protein N-terminal zf-trcl PF13451.4 001266619.2_29624001_3 - 0.0019 17.9 28.0 1.5 8.7 2.7 7.7 7 1 0 7 7 7 1 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.8 001266619.2_29624001_3 - 0.0029 17.5 46.8 0.01 15.8 3.4 7.4 5 2 5 10 10 10 4 Zinc ribbon domain zf-LYAR PF08790.9 001266619.2_29624001_3 - 0.036 13.9 40.9 0.81 9.5 0.4 9.4 10 0 0 10 10 10 0 LYAR-type C2HC zinc finger zinc_ribbon_15 PF17032.3 001266619.2_29624001_3 - 0.043 14.4 42.9 0.27 11.9 2.3 6.1 2 2 4 6 6 6 0 zinc-ribbon family zf-met PF12874.5 001266619.2_29624001_3 - 0.42 10.9 68.1 0.1 12.9 0.9 10.5 12 0 0 12 12 11 0 Zinc-finger of C2H2 type YhfH PF14149.4 001266619.2_29624001_3 - 0.44 10.4 28.3 14 5.6 0.1 8.3 8 0 0 8 8 8 0 YhfH-like protein zf-C2HE PF16278.3 001266619.2_29624001_3 - 2.1 8.7 45.0 1.7 9.0 0.1 8.8 4 2 3 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger DUF1163 PF06651.9 001266619.2_29624001_3 - 7.4 6.6 9.9 0.75 9.8 0.1 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1163) Pkinase PF00069.23 001261495.1_29624001_3 - 4.9e-62 209.5 0.1 2.1e-61 207.5 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001261495.1_29624001_3 - 7.9e-29 100.6 2.3 2.7e-20 72.6 0.2 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.22 001261495.1_29624001_3 - 6.9e-07 29.7 2.1 9.8e-07 29.2 1.2 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.4 001261495.1_29624001_3 - 9.3e-06 25.0 0.7 0.00022 20.5 0.1 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.21 001261495.1_29624001_3 - 0.00037 20.3 0.9 0.036 13.9 0.2 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.12 001261495.1_29624001_3 - 0.0013 18.0 0.1 0.0027 17.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001261495.1_29624001_3 - 0.061 12.8 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.9 001261495.1_29624001_3 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PCI PF01399.25 001261496.2_29624001_3 - 4.2e-05 23.9 0.2 0.00013 22.3 0.0 1.8 2 0 0 2 2 2 1 PCI domain DUF4200 PF13863.4 001261496.2_29624001_3 - 0.078 13.2 0.3 0.15 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) zf-H2C2_2 PF13465.4 001266621.1_29626001_1 - 0.001 19.3 0.9 0.001 19.3 0.9 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_2 PF13465.4 001266621.1_29626001_2 - 5.3e-26 89.7 79.6 5.4e-08 32.8 2.0 11.5 11 0 0 11 11 11 8 Zinc-finger double domain zf-C2H2 PF00096.24 001266621.1_29626001_2 - 8.5e-23 79.4 76.7 2.3e-05 24.4 2.6 9.3 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001266621.1_29626001_2 - 2.3e-11 43.4 66.2 0.0034 18.0 2.4 8.0 8 0 0 8 8 8 6 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001266621.1_29626001_2 - 7.4e-05 22.7 31.4 0.017 15.1 1.6 4.9 3 1 1 4 4 4 3 Zinc ribbon domain zf-C2H2_6 PF13912.4 001266621.1_29626001_2 - 0.0027 17.5 47.9 0.11 12.4 2.1 7.1 6 1 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001266621.1_29626001_2 - 0.0056 16.8 20.2 0.62 10.3 0.4 5.6 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001266621.1_29626001_2 - 0.026 14.2 0.7 0.026 14.2 0.7 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type XPA_N PF01286.16 001266621.1_29626001_2 - 0.89 9.5 32.2 7.3 6.6 0.6 6.8 7 0 0 7 7 7 0 XPA protein N-terminal zf-C2H2 PF00096.24 001266621.1_29626001_3 - 0.012 15.9 9.6 0.02 15.2 1.4 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001266621.1_29626001_3 - 2.2 8.7 6.9 0.96 9.9 1.0 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.4 001266621.1_29626001_3 - 2.3 9.2 6.5 2.6 9.0 1.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Opiods_neuropep PF01160.16 001257884.1_29625001_3 - 5.5e-16 58.3 6.3 1.2e-15 57.2 6.3 1.6 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide RPAP2_Rtr1 PF04181.11 001257890.1_29626001_1 - 2.9e-23 81.8 0.4 8.5e-23 80.3 0.4 1.9 1 0 0 1 1 1 1 Rtr1/RPAP2 family NAD_Gly3P_dh_N PF01210.21 001257890.1_29626001_1 - 0.12 12.3 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DDE_Tnp_4 PF13359.4 001261506.2_29623001_3 - 1e-37 129.1 0.0 1.5e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.12 001261506.2_29623001_3 - 4.1e-07 29.7 0.0 8.3e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 Plant transposon protein Myotub-related PF06602.12 001257894.1_29629001_1 - 2.2e-153 510.1 0.0 2.9e-153 509.7 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.18 001257894.1_29629001_1 - 9.4e-20 70.4 0.0 1.8e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.25 001257894.1_29629001_1 - 0.00062 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3-PAP PF12578.6 001257894.1_29629001_1 - 0.0039 16.8 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Myotubularin-associated protein DSPc PF00782.18 001257894.1_29629001_1 - 0.0096 15.6 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.4 001257894.1_29629001_1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family NYD-SP28_assoc PF14775.4 001257894.1_29629001_1 - 0.3 11.1 2.0 2.7 8.0 0.6 2.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain BTB_3 PF16017.3 001257899.1_29628001_2 - 1.1e-48 163.6 0.0 1.7e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.20 001257899.1_29628001_2 - 0.00022 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SLY PF12485.6 001261510.1_29626001_3 - 5.9e-46 156.9 2.3 1e-45 156.1 2.3 1.4 1 0 0 1 1 1 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.15 001261510.1_29626001_3 - 5.5e-08 32.7 0.2 8.6e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001261510.1_29626001_3 - 5.5e-08 33.0 0.1 9.4e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.15 001261510.1_29626001_3 - 1.3e-07 31.1 0.0 2.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001261510.1_29626001_3 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 001261510.1_29626001_3 - 0.022 14.5 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain AA_permease_2 PF13520.4 001257912.1_29628001_1 - 1.5e-43 149.1 39.2 1.5e-43 149.1 39.2 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.19 001257912.1_29628001_1 - 4.7e-37 127.6 37.7 4.7e-37 127.6 37.7 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.4 001257912.1_29628001_1 - 1.7e-20 72.7 10.1 1.7e-20 72.7 10.1 3.6 5 0 0 5 5 5 1 C-terminus of AA_permease Popeye PF04831.11 001257913.1_29624001_3 - 1.2e-47 161.4 2.3 1.7e-47 161.0 2.3 1.2 1 0 0 1 1 1 1 Popeye protein conserved region Phage_holin_3_6 PF07332.9 001257913.1_29624001_3 - 4.1 7.3 6.6 7.2 6.5 6.6 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III THAP PF05485.10 001261521.1_29622001_3 - 1.1e-12 48.6 0.1 1.1e-12 48.6 0.1 1.8 2 0 0 2 2 2 1 THAP domain DUF4686 PF15742.3 001261521.1_29622001_3 - 0.0096 14.9 0.5 0.013 14.5 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) DUF3338 PF11819.6 001261521.1_29622001_3 - 0.096 12.6 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) Serine_rich PF08824.8 001261521.1_29622001_3 - 0.12 12.2 0.8 0.83 9.5 0.7 2.0 1 1 1 2 2 2 0 Serine rich protein interaction domain Prefoldin_2 PF01920.18 001261521.1_29622001_3 - 0.14 12.0 2.1 0.22 11.4 2.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit IncA PF04156.12 001261521.1_29622001_3 - 0.16 11.6 1.6 0.23 11.1 1.6 1.1 1 0 0 1 1 1 0 IncA protein Peroxin-3 PF04882.10 001257927.1_29625001_2 - 4.6e-67 226.9 6.8 1.7e-45 155.8 1.5 3.0 1 1 1 2 2 2 2 Peroxin-3 CENP-L PF13092.4 001261531.1_29624001_1 - 4.8e-33 114.5 0.1 7.4e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Arrestin_N PF00339.27 001257935.1_29626001_2 - 9.6e-24 84.0 0.1 1.8e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 001257935.1_29626001_2 - 1.9e-11 44.3 0.0 1.3e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DER1 PF04511.13 001257937.1_29627001_2 - 1.5e-64 217.2 12.4 1.5e-64 217.2 12.4 1.7 2 0 0 2 2 2 1 Der1-like family LrgA PF03788.12 001257937.1_29627001_2 - 4.4 7.2 7.3 7.1 6.5 1.6 2.6 2 0 0 2 2 2 0 LrgA family Porphobil_deam PF01379.18 001266660.1_29624001_2 - 4.1e-78 261.5 0.1 5.3e-78 261.1 0.1 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.13 001266660.1_29624001_2 - 1.5e-21 76.4 0.0 5.4e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain MGS PF02142.20 001266660.1_29624001_2 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 MGS-like domain eRF1_2 PF03464.13 001266660.1_29624001_2 - 0.16 12.2 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 eRF1 domain 2 DUF788 PF05620.9 001261539.1_29622001_2 - 1.5e-52 177.7 0.1 1.8e-52 177.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) 2TM PF13239.4 001261539.1_29622001_2 - 0.075 13.2 1.9 1.6 9.0 0.6 2.2 2 0 0 2 2 2 0 2TM domain Halogen_Hydrol PF10112.7 001261539.1_29622001_2 - 1.1 9.1 4.2 0.62 9.9 1.4 1.8 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TMEM117 PF15113.4 001261543.1_29626001_2 - 2.6e-231 767.6 28.7 3.3e-231 767.2 28.7 1.1 1 0 0 1 1 1 1 TMEM117 protein family BCHF PF07284.9 001261543.1_29626001_2 - 0.019 14.8 1.6 0.071 13.0 1.6 2.0 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Crystall_2 PF09076.8 001257945.2_29623001_1 - 0.17 11.7 0.7 0.48 10.3 0.1 1.9 2 0 0 2 2 2 0 Beta/Gamma crystallin V-SNARE_C PF12352.6 001257945.2_29623001_2 - 2.5e-22 78.8 2.9 2.5e-22 78.8 2.9 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.11 001257945.2_29623001_2 - 0.046 13.5 0.7 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 Sec20 Steroid_dh PF02544.14 001257949.1_29623001_1 - 3.5e-20 72.4 11.2 4.1e-20 72.2 10.2 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1729 PF08354.8 001257949.1_29623001_3 - 0.081 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) BTB PF00651.29 001266696.1_29624001_2 - 2e-20 72.9 0.0 4.7e-20 71.7 0.0 1.5 2 0 0 2 2 1 1 BTB/POZ domain zf-C2H2 PF00096.24 001266696.1_29624001_2 - 6.6e-18 64.0 30.1 1.1e-05 25.4 1.1 4.9 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001266696.1_29624001_2 - 2.2e-17 62.5 21.4 6.6e-05 23.1 0.2 4.9 5 0 0 5 5 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 001266696.1_29624001_2 - 9.2e-13 47.7 27.1 0.0016 18.9 1.2 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001266696.1_29624001_2 - 2.9e-07 30.5 7.5 0.014 15.5 1.8 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001266696.1_29624001_2 - 6.6e-05 22.6 23.7 0.0085 15.9 0.3 4.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.5 001266696.1_29624001_2 - 0.0001 22.4 21.2 0.25 11.7 1.1 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 001266696.1_29624001_2 - 0.00011 21.8 16.5 0.24 11.1 0.6 4.5 4 0 0 4 4 4 2 zinc-finger C2H2-type DUF2256 PF10013.7 001266696.1_29624001_2 - 0.00024 21.0 11.0 1.2 9.2 0.2 4.2 4 0 0 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.8 001266696.1_29624001_2 - 0.0048 16.8 9.6 0.015 15.3 1.3 2.6 2 0 0 2 2 2 1 Zinc ribbon domain zf-C2H2_2 PF12756.5 001266696.1_29624001_2 - 0.013 15.7 15.1 0.42 10.8 12.0 3.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.10 001266696.1_29624001_2 - 0.38 10.9 15.5 8.8 6.6 0.3 3.4 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding CENP-B_dimeris PF09026.8 001266696.1_29624001_2 - 0.77 10.0 4.2 7.8 6.8 5.0 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HypA PF01155.17 001266696.1_29624001_2 - 1.1 9.1 7.6 3 7.8 2.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.3 001266696.1_29624001_2 - 1.8 9.3 7.6 13 6.5 1.4 2.3 1 1 1 2 2 2 0 zinc-ribbon family Zn_Tnp_IS1595 PF12760.5 001266696.1_29624001_2 - 2 8.3 10.4 9.3 6.2 0.1 3.6 3 1 0 3 3 3 0 Transposase zinc-ribbon domain LIM PF00412.20 001266696.1_29624001_2 - 3.2 7.9 8.6 8.7 6.5 3.0 3.0 1 1 1 3 3 3 0 LIM domain zf-C2HC_2 PF13913.4 001266696.1_29624001_2 - 5.5 6.9 10.9 10 6.0 0.0 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type WH1 PF00568.21 001261570.1_29623001_3 - 1.5e-35 121.3 0.2 2.9e-35 120.4 0.2 1.4 1 0 0 1 1 1 1 WH1 domain GAS PF13851.4 001261570.1_29623001_3 - 0.00011 21.5 29.8 0.00011 21.5 29.8 2.1 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.9 001261570.1_29623001_3 - 0.00084 17.9 21.0 0.00084 17.9 21.0 1.7 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like HMMR_N PF15905.3 001261570.1_29623001_3 - 0.00087 18.7 24.4 0.00087 18.7 24.4 1.9 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal BLOC1_2 PF10046.7 001261570.1_29623001_3 - 0.02 15.0 7.1 0.02 15.0 7.1 3.4 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.10 001261570.1_29623001_3 - 0.025 14.4 16.3 0.38 10.6 9.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3508 PF12018.6 001261570.1_29623001_3 - 0.11 11.9 20.4 0.56 9.5 9.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3508) Reo_sigmaC PF04582.10 001261570.1_29623001_3 - 0.13 11.5 7.1 1.3 8.2 1.6 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Nsp1_C PF05064.11 001261570.1_29623001_3 - 0.13 11.9 24.2 1 9.0 11.9 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region FUSC PF04632.10 001261570.1_29623001_3 - 0.14 10.5 7.8 0.2 10.0 7.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.9 001261570.1_29623001_3 - 0.44 10.6 41.1 4.6 7.2 22.4 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.10 001261570.1_29623001_3 - 0.53 10.6 13.0 0.95 9.8 1.1 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.8 001261570.1_29623001_3 - 0.58 10.2 17.9 1.4 9.0 11.8 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tmemb_cc2 PF10267.7 001261570.1_29623001_3 - 0.64 9.0 32.8 3.3 6.6 32.5 2.0 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TMF_TATA_bd PF12325.6 001261570.1_29623001_3 - 0.95 9.6 37.0 0.052 13.6 21.4 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.10 001261570.1_29623001_3 - 1.1 8.4 36.5 0.068 12.4 21.3 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 Prominin PF05478.9 001261570.1_29623001_3 - 1.2 6.8 11.1 2.1 6.0 11.1 1.4 1 0 0 1 1 1 0 Prominin HemX PF04375.12 001261570.1_29623001_3 - 1.3 8.1 24.4 0.32 10.1 9.9 2.4 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase CENP-K PF11802.6 001261570.1_29623001_3 - 1.8 7.9 26.7 0.13 11.7 21.6 1.6 2 0 0 2 2 2 0 Centromere-associated protein K EzrA PF06160.10 001261570.1_29623001_3 - 2 6.4 28.2 0.032 12.3 19.1 2.1 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA IFT57 PF10498.7 001261570.1_29623001_3 - 2 7.2 29.6 3 6.6 5.5 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4407 PF14362.4 001261570.1_29623001_3 - 2.3 7.4 19.7 5 6.3 19.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.10 001261570.1_29623001_3 - 2.5 8.0 21.6 0.25 11.2 9.0 2.8 2 1 1 3 3 3 0 Laminin Domain II Fmp27_WPPW PF10359.7 001261570.1_29623001_3 - 2.7 6.6 18.3 5.8 5.5 17.5 1.8 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Fzo_mitofusin PF04799.11 001261570.1_29623001_3 - 2.8 7.3 21.0 1.6 8.1 12.9 2.8 1 1 2 3 3 3 0 fzo-like conserved region Phlebovirus_NSM PF07246.9 001261570.1_29623001_3 - 3.9 6.6 14.4 3.9 6.6 12.9 1.7 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Phage_GP20 PF06810.9 001261570.1_29623001_3 - 4 7.1 24.8 16 5.1 14.3 3.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF641 PF04859.10 001261570.1_29623001_3 - 4.3 7.6 23.1 2.8 8.1 10.0 3.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF342 PF03961.11 001261570.1_29623001_3 - 4.9 5.5 20.5 26 3.1 20.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF342) CENP-F_leu_zip PF10473.7 001261570.1_29623001_3 - 5.3 6.9 39.3 0.33 10.9 29.5 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlgM PF04316.11 001261570.1_29623001_3 - 5.4 7.3 9.6 0.49 10.7 1.3 3.0 3 1 0 3 3 2 0 Anti-sigma-28 factor, FlgM DUF489 PF04356.10 001261570.1_29623001_3 - 5.6 6.8 11.1 2.1 8.2 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Cluap1 PF10234.7 001261570.1_29623001_3 - 5.6 6.1 28.4 1.9 7.7 8.7 2.4 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF4763 PF15960.3 001261570.1_29623001_3 - 7.2 5.7 23.7 1.9 7.6 1.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Macoilin PF09726.7 001261570.1_29623001_3 - 8 4.7 25.8 0.42 9.0 14.8 2.0 1 1 1 2 2 2 0 Transmembrane protein DUF948 PF06103.9 001261570.1_29623001_3 - 8.3 6.6 12.6 16 5.7 3.2 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4164 PF13747.4 001261570.1_29623001_3 - 9.3 6.5 25.8 0.91 9.7 14.2 3.4 2 1 2 4 4 3 0 Domain of unknown function (DUF4164) DMPK_coil PF08826.8 001261570.1_29623001_3 - 9.3 6.3 24.9 2.4 8.2 15.4 3.4 2 1 1 3 3 3 0 DMPK coiled coil domain like IncA PF04156.12 001261570.1_29623001_3 - 9.7 5.8 41.3 11 5.6 34.1 2.8 2 1 0 2 2 2 0 IncA protein RabGAP-TBC PF00566.16 001258065.1_29629001_1 - 1.2e-52 178.5 0.8 2.6e-52 177.5 0.8 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3350 PF11830.6 001258065.1_29629001_1 - 2.3e-22 78.9 2.0 9.8e-22 76.9 2.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3350) PID PF00640.21 001258065.1_29629001_1 - 1.6e-12 47.5 4.0 6.6e-08 32.6 0.2 2.8 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) Shugoshin_N PF07558.9 001258065.1_29629001_1 - 0.46 10.3 5.7 8.5 6.2 1.8 3.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Acetyltransf_11 PF13720.4 001258065.1_29629001_1 - 1 9.8 3.8 5.3 7.5 0.5 3.3 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GCR1_C PF12550.6 001258065.1_29629001_2 - 0.033 14.4 0.1 0.072 13.3 0.1 1.4 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes NOA36 PF06524.10 001266710.1_29623001_2 - 3.4e-161 535.7 46.4 4.4e-161 535.3 46.4 1.1 1 0 0 1 1 1 1 NOA36 protein MBOAT PF03062.17 001261586.1_29624001_1 - 3.1e-72 243.7 12.9 9.7e-72 242.1 12.9 1.9 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Kelch_1 PF01344.23 001261588.1_29626001_2 - 7.9e-45 150.1 11.2 1.3e-11 43.7 0.1 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.4 001261588.1_29626001_2 - 7.5e-38 127.5 4.0 3.9e-07 30.0 0.0 5.6 4 1 1 5 5 5 5 Kelch motif BTB PF00651.29 001261588.1_29626001_2 - 4.4e-27 94.4 1.2 3.9e-25 88.1 0.2 2.4 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.4 001261588.1_29626001_2 - 1.5e-24 85.6 4.9 2.6e-09 37.0 0.1 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.13 001261588.1_29626001_2 - 1.9e-22 78.2 6.6 1e-06 28.3 0.1 5.9 5 1 0 5 5 5 4 Kelch motif BACK PF07707.13 001261588.1_29626001_2 - 6.8e-16 58.1 0.6 1.4e-15 57.1 0.6 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.4 001261588.1_29626001_2 - 8.7e-16 57.5 2.0 0.0069 16.2 0.0 5.5 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.4 001261588.1_29626001_2 - 1.7e-07 30.9 1.9 0.3 11.0 0.0 5.3 5 0 0 5 5 5 2 Kelch motif 7tm_1 PF00001.19 001266718.1_29624001_1 - 1.7e-31 109.3 9.6 2.3e-31 108.9 9.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001266718.1_29624001_1 - 1.4e-08 34.3 4.0 2.2e-08 33.7 4.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001266718.1_29624001_1 - 5.2e-06 26.3 3.3 5.1e-05 23.0 3.3 2.1 1 1 0 1 1 1 1 Olfactory receptor PRA1 PF03208.17 001266718.1_29624001_1 - 4.1 6.9 13.2 0.34 10.4 3.6 2.9 3 0 0 3 3 3 0 PRA1 family protein CHCH PF06747.11 001258084.1_29622001_2 - 8.6e-09 35.2 3.0 1.4e-08 34.5 3.0 1.4 1 0 0 1 1 1 1 CHCH domain Colipase-like PF15083.4 001258084.1_29622001_2 - 0.079 13.0 0.5 0.11 12.6 0.5 1.2 1 0 0 1 1 1 0 Colipase-like Mito_carr PF00153.25 001258085.1_29627001_2 - 4.3e-74 244.4 3.7 6.1e-26 90.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.30 001258085.1_29627001_2 - 3.7e-19 66.6 6.1 3.3e-05 23.0 1.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001258085.1_29627001_2 - 7.4e-19 67.9 1.9 4.6e-09 36.5 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001258085.1_29627001_2 - 5.9e-18 63.1 7.2 0.00016 21.2 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.4 001258085.1_29627001_2 - 1.7e-14 52.4 9.2 0.00018 20.8 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.4 001258085.1_29627001_2 - 6.1e-12 45.0 3.1 1.1e-06 28.1 0.7 3.7 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001258085.1_29627001_2 - 1.1e-06 28.9 0.0 0.034 14.3 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001258085.1_29627001_2 - 0.00012 21.8 0.5 0.0016 18.3 0.0 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.4 001258085.1_29627001_2 - 0.00052 19.7 0.4 0.18 11.6 0.0 3.1 2 2 1 3 3 3 1 EF hand Sigma_reg_C PF13791.4 001258085.1_29627001_2 - 0.034 14.3 0.1 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 Sigma factor regulator C-terminal EF-hand_9 PF14658.4 001258085.1_29627001_2 - 0.037 14.2 0.0 17 5.7 0.0 2.8 2 1 0 2 2 2 0 EF-hand domain DUF1356 PF07092.10 001266724.1_29623001_2 - 4.1e-102 340.2 2.4 5.6e-102 339.8 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.11 001266724.1_29623001_2 - 0.0055 17.0 0.2 0.01 16.2 0.2 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Anti-TRAP PF15777.3 001266724.1_29623001_2 - 0.019 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF3446 PF11928.6 001258086.1_29626001_3 - 3.9e-24 84.6 6.5 3.9e-24 84.6 6.5 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3446) zf-C2H2 PF00096.24 001258086.1_29626001_3 - 3.2e-15 55.5 16.7 6.8e-06 26.1 0.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001258086.1_29626001_3 - 4.7e-12 45.6 29.0 8.8e-08 32.1 1.6 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001258086.1_29626001_3 - 4.9e-10 39.2 12.9 0.0055 17.3 2.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.13 001258086.1_29626001_3 - 0.015 15.2 9.8 0.033 14.1 4.1 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.4 001258086.1_29626001_3 - 0.033 14.0 4.1 5.6 6.9 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001258086.1_29626001_3 - 0.035 14.3 3.0 32 4.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.4 001258086.1_29626001_3 - 0.036 13.8 10.5 0.42 10.4 0.5 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.3 001258086.1_29626001_3 - 6.5 6.5 7.6 40 4.0 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type PH PF00169.27 001266727.2_29628001_3 - 1.1e-11 45.1 0.1 1.8e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 001266727.2_29628001_3 - 0.018 15.3 0.1 0.046 14.0 0.1 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Lung_7-TM_R PF06814.11 001261600.1_29626001_1 - 1.4e-84 283.7 19.9 1.8e-84 283.3 19.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SPT6_acidic PF14632.4 001261600.1_29626001_1 - 0.073 13.5 1.2 0.15 12.6 1.2 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 LSM14 PF12701.5 001261605.1_29625001_3 - 8.4e-31 105.8 0.0 1.4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.8 001261605.1_29625001_3 - 1.1e-24 87.1 8.0 1.1e-24 87.1 8.0 1.6 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.4 001261605.1_29625001_3 - 4.9e-08 32.9 0.0 9.2e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain GST_C_2 PF13410.4 001261607.1_29626001_1 - 3.6e-06 26.7 0.0 6.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001261607.1_29626001_1 - 0.00092 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001261607.1_29626001_1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001261607.1_29626001_1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mnd1 PF03962.13 001258106.1_29622001_3 - 6.4e-71 238.0 7.4 7.5e-71 237.7 7.4 1.1 1 0 0 1 1 1 1 Mnd1 family DivIC PF04977.13 001258106.1_29622001_3 - 2e-05 24.1 10.2 0.0009 18.8 2.0 3.3 1 1 2 3 3 3 3 Septum formation initiator Penicillinase_R PF03965.14 001258106.1_29622001_3 - 4.9e-05 23.5 0.4 8.3e-05 22.8 0.4 1.4 1 0 0 1 1 1 1 Penicillinase repressor TBPIP PF07106.11 001258106.1_29622001_3 - 0.00011 21.9 4.4 0.00016 21.3 4.4 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TFIIE_alpha PF02002.15 001258106.1_29622001_3 - 0.017 14.8 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 TFIIE alpha subunit DsrD PF08679.9 001258106.1_29622001_3 - 0.031 14.4 0.1 0.084 13.0 0.1 1.7 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) TrmB PF01978.17 001258106.1_29622001_3 - 0.031 14.0 0.0 0.087 12.6 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SOGA PF11365.6 001258106.1_29622001_3 - 0.049 14.6 1.8 0.049 14.6 1.8 2.0 1 1 0 1 1 1 0 Protein SOGA RasGAP_C PF03836.13 001258106.1_29622001_3 - 0.094 12.7 4.5 0.049 13.7 1.3 2.0 1 1 1 2 2 2 0 RasGAP C-terminus DUF4407 PF14362.4 001258106.1_29622001_3 - 0.12 11.6 1.1 0.15 11.2 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin PF02996.15 001258106.1_29622001_3 - 0.12 12.2 3.0 8.3 6.2 1.0 2.5 2 1 0 2 2 2 0 Prefoldin subunit DUF2959 PF11172.6 001258106.1_29622001_3 - 0.13 12.1 4.5 0.25 11.2 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) DUF342 PF03961.11 001258106.1_29622001_3 - 0.17 10.3 2.8 0.26 9.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.10 001258106.1_29622001_3 - 0.22 10.8 7.9 0.3 10.3 7.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.12 001258106.1_29622001_3 - 0.25 11.0 9.4 0.38 10.4 9.4 1.2 1 0 0 1 1 1 0 IncA protein LPP PF04728.11 001258106.1_29622001_3 - 0.31 11.3 4.8 0.25 11.6 0.6 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Spc7 PF08317.9 001258106.1_29622001_3 - 0.42 9.3 15.2 0.19 10.4 11.6 2.0 2 1 0 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.9 001258106.1_29622001_3 - 0.61 10.4 3.1 2.9 8.2 0.2 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.7 001258106.1_29622001_3 - 0.97 8.3 7.5 1.4 7.8 7.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 WD40 PF00400.30 001258112.1_29623001_1 - 8.9e-48 159.1 26.8 1e-10 41.9 0.6 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001258112.1_29623001_1 - 4.1e-21 75.0 2.4 2.9e-05 24.1 0.2 6.4 1 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001258112.1_29623001_1 - 4.9e-06 26.4 0.1 0.0066 16.2 0.1 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.10 001258112.1_29623001_1 - 2.9e-05 22.2 1.1 6.9e-05 20.9 0.8 1.7 1 1 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.3 001258112.1_29623001_1 - 4.8e-05 22.4 2.0 0.99 8.2 0.0 4.8 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.12 001258112.1_29623001_1 - 0.00025 20.1 1.1 0.1 11.5 0.0 2.3 1 1 1 2 2 2 2 Coatomer WD associated region Vps36-NZF-N PF16988.3 001258112.1_29623001_3 - 0.8 9.0 3.6 8 5.8 0.1 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3456 PF11938.6 001266755.1_29623001_3 - 7.6e-48 162.9 0.3 1.1e-47 162.3 0.3 1.2 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_1 PF05184.13 001266755.1_29623001_3 - 0.15 12.0 1.8 13 5.7 0.0 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 Rep_fac_C PF08542.9 001258122.2_29623001_2 - 3.2e-26 91.4 0.0 6.9e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.27 001258122.2_29623001_2 - 2.9e-13 50.3 0.1 5e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.4 001258122.2_29623001_2 - 1.3e-11 44.4 0.0 2e-10 40.5 0.0 2.1 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.4 001258122.2_29623001_2 - 3.6e-06 27.3 0.0 0.00045 20.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.13 001258122.2_29623001_2 - 4.1e-06 25.9 0.0 0.0038 16.1 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.4 001258122.2_29623001_2 - 4.7e-06 26.5 0.0 8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.4 001258122.2_29623001_2 - 1.4e-05 25.3 0.2 0.04 14.0 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.4 001258122.2_29623001_2 - 5.7e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.16 001258122.2_29623001_2 - 8.2e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.19 001258122.2_29623001_2 - 0.00011 21.5 0.0 0.0013 18.0 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.4 001258122.2_29623001_2 - 0.00016 21.4 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.10 001258122.2_29623001_2 - 0.00028 20.1 0.0 0.00059 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_assoc_2 PF16193.3 001258122.2_29623001_2 - 0.00037 20.6 0.0 0.00089 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.4 001258122.2_29623001_2 - 0.0013 19.0 0.3 0.0079 16.4 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001258122.2_29623001_2 - 0.0018 18.6 0.0 0.0044 17.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.12 001258122.2_29623001_2 - 0.0032 17.3 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.4 001258122.2_29623001_2 - 0.0066 15.9 0.3 0.017 14.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain MipZ PF09140.9 001258122.2_29623001_2 - 0.0069 15.6 0.0 0.0096 15.1 0.0 1.1 1 0 0 1 1 1 1 ATPase MipZ AAA_30 PF13604.4 001258122.2_29623001_2 - 0.01 15.4 0.2 0.027 14.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.27 001258122.2_29623001_2 - 0.015 15.0 0.9 0.56 9.8 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase TniB PF05621.9 001258122.2_29623001_2 - 0.017 14.2 0.1 5.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.25 001258122.2_29623001_2 - 0.026 14.9 0.0 0.058 13.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter T2SSE PF00437.18 001258122.2_29623001_2 - 0.035 13.0 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.4 001258122.2_29623001_2 - 0.054 13.6 0.2 0.094 12.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.13 001258122.2_29623001_2 - 0.067 13.0 0.2 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 NTPase ArgK PF03308.14 001258122.2_29623001_2 - 0.085 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF815 PF05673.11 001258122.2_29623001_2 - 0.095 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2075 PF09848.7 001258122.2_29623001_2 - 0.099 11.7 0.6 1.8 7.6 0.6 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.16 001258122.2_29623001_2 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.20 001258122.2_29623001_2 - 0.14 12.4 0.0 0.41 10.9 0.0 1.9 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.13 001258122.2_29623001_2 - 0.15 11.9 0.2 23 4.8 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.4 001258122.2_29623001_2 - 0.16 12.3 0.0 0.25 11.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF4597 PF15366.4 001258122.2_29623001_2 - 0.22 11.2 0.4 8.9 6.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) Rib_5-P_isom_A PF06026.12 001258126.1_29623001_3 - 2.3e-65 219.3 0.0 2.9e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.11 001258126.1_29623001_3 - 0.0026 16.8 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain DeoRC PF00455.20 001258126.1_29623001_3 - 0.01 15.6 0.1 0.048 13.5 0.1 1.9 1 1 1 2 2 2 0 DeoR C terminal sensor domain SERTA PF06031.11 001266761.2_29623001_2 - 9e-14 50.7 0.6 1.6e-13 49.9 0.6 1.5 1 0 0 1 1 1 1 SERTA motif TRAPP PF04051.14 001266767.2_29623001_1 - 6.5e-36 123.1 0.0 8.3e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component COX7B PF05392.9 001258140.1_29621001_1 - 1.3e-43 146.3 0.1 1.7e-43 146.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB DUF3025 PF11227.6 001258140.1_29621001_1 - 0.064 12.9 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Deltameth_res PF16020.3 001258140.1_29621001_1 - 0.1 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Deltamethrin resistance zf-LYAR PF08790.9 001258141.1_29624001_3 - 1.3e-15 56.8 1.6 1.3e-15 56.8 1.6 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DEK_C PF08766.9 001258141.1_29624001_3 - 0.021 14.6 0.2 0.097 12.5 0.1 2.2 2 0 0 2 2 2 0 DEK C terminal domain Mut7-C PF01927.14 001258141.1_29624001_3 - 0.12 12.4 4.3 0.28 11.1 4.3 1.7 1 0 0 1 1 1 0 Mut7-C RNAse domain ABC_transp_aux PF09822.7 001261644.1_29624001_3 - 1.1e-10 41.3 0.1 1.9e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.12 001261644.1_29624001_3 - 0.0069 15.1 0.0 0.41 9.3 0.0 2.2 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta ACC_central PF08326.10 001266778.1_29629001_3 - 1.3e-284 945.7 9.2 1.7e-284 945.4 9.2 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.20 001266778.1_29629001_3 - 1.4e-183 610.9 0.0 1.9e-183 610.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.15 001266778.1_29629001_3 - 3.4e-54 183.4 0.0 6.8e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.20 001266778.1_29629001_3 - 4e-31 107.7 0.0 8.3e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.17 001266778.1_29629001_3 - 1.8e-22 79.4 0.0 8.7e-22 77.1 0.0 2.3 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.20 001266778.1_29629001_3 - 6.5e-17 61.0 0.0 1.8e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.4 001266778.1_29629001_3 - 4.9e-07 28.6 0.0 0.0053 15.4 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.11 001266778.1_29629001_3 - 7.8e-06 25.4 0.0 1.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.20 001266778.1_29629001_3 - 9.2e-06 25.2 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.12 001266778.1_29629001_3 - 5.7e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain DUF445 PF04286.10 001266778.1_29629001_3 - 1.1 8.9 3.9 5.9 6.5 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF445) MAPEG PF01124.16 001266781.2_29622001_3 - 3.8e-24 84.9 0.5 5.1e-24 84.5 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Pro_isomerase PF00160.19 001258155.1_29625001_1 - 2.2e-37 128.7 0.2 3.9e-37 127.8 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.20 001258155.1_29625001_1 - 2.9e-17 62.1 0.0 5.5e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCCAP PF15964.3 001258164.1_29626001_3 - 4.1 5.4 113.6 0.0097 14.1 12.2 2.9 1 1 2 3 3 3 0 Centrosomal colon cancer autoantigen protein family AD PF09793.7 001266793.1_29623001_1 - 3.6e-24 84.6 0.4 6.3e-24 83.8 0.4 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.10 001266793.1_29623001_1 - 0.03 13.7 0.0 0.068 12.6 0.0 1.6 2 0 0 2 2 2 0 Gemin6 protein Gcd10p PF04189.11 001261660.1_29625001_2 - 1.6e-72 244.0 0.4 3e-72 243.1 0.3 1.5 1 1 0 1 1 1 1 Gcd10p family Rep_fac_C PF08542.9 001261662.1_29624001_3 - 8e-25 86.9 0.2 1.2e-23 83.2 0.1 2.4 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.27 001261662.1_29624001_3 - 1.8e-15 57.4 0.0 3.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.4 001261662.1_29624001_3 - 5.6e-14 52.1 0.0 1.3e-10 41.2 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.13 001261662.1_29624001_3 - 1.3e-11 44.0 0.0 4.7e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_24 PF13479.4 001261662.1_29624001_3 - 2.7e-06 27.1 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.3 001261662.1_29624001_3 - 2.8e-06 27.4 0.0 6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.4 001261662.1_29624001_3 - 1.2e-05 25.7 0.0 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.4 001261662.1_29624001_3 - 2.5e-05 24.0 0.0 0.00023 20.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.10 001261662.1_29624001_3 - 3.9e-05 22.9 0.0 7.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.4 001261662.1_29624001_3 - 6.6e-05 23.1 0.4 0.026 14.7 0.2 2.7 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.11 001261662.1_29624001_3 - 0.00056 19.0 0.0 0.0009 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.13 001261662.1_29624001_3 - 0.00056 19.8 0.0 0.076 12.9 0.0 2.2 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.4 001261662.1_29624001_3 - 0.0014 18.8 0.4 0.038 14.2 0.0 2.6 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.11 001261662.1_29624001_3 - 0.0016 17.3 0.0 0.023 13.5 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.4 001261662.1_29624001_3 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.12 001261662.1_29624001_3 - 0.0028 17.5 0.1 0.017 15.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.11 001261662.1_29624001_3 - 0.0034 17.1 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.27 001261662.1_29624001_3 - 0.0048 16.6 0.1 0.08 12.6 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.14 001261662.1_29624001_3 - 0.0069 15.7 0.1 0.12 11.7 0.0 2.2 1 1 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.4 001261662.1_29624001_3 - 0.0083 15.7 0.0 0.084 12.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain TniB PF05621.9 001261662.1_29624001_3 - 0.019 14.0 0.0 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.15 001261662.1_29624001_3 - 0.053 13.2 0.0 0.36 10.4 0.0 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.18 001261662.1_29624001_3 - 0.055 12.4 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.16 001261662.1_29624001_3 - 0.097 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.19 001261662.1_29624001_3 - 0.16 11.2 0.1 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PUB PF09409.8 001258169.1_29624001_3 - 2.9e-24 84.7 0.1 5.9e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 PUB domain UBX PF00789.18 001258169.1_29624001_3 - 7.3e-08 32.4 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain Peroxin-13_N PF04088.11 001258170.1_29625001_3 - 3.9e-45 153.5 0.3 6.1e-45 152.9 0.3 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.4 001258170.1_29625001_3 - 1.1e-10 41.1 0.0 1.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001258170.1_29625001_3 - 5.3e-08 32.2 0.0 9.1e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001258170.1_29625001_3 - 5.1e-05 22.8 0.0 9.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Snf7 PF03357.19 001266802.1_29624001_1 - 6e-43 146.3 24.1 9.8e-43 145.6 24.1 1.3 1 0 0 1 1 1 1 Snf7 DnaJ-X PF14308.4 001266802.1_29624001_1 - 6.6e-05 22.3 8.2 0.00013 21.4 8.2 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing Rdx PF10262.7 001266804.1_29622001_2 - 1.4e-17 63.5 0.0 1.8e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Rdx family ubiquitin PF00240.21 001266806.1_29622001_3 - 5.2e-34 115.7 0.0 1e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.6 001266806.1_29622001_3 - 1.5e-06 27.8 0.0 0.005 16.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001266806.1_29622001_3 - 9.9e-06 25.8 0.1 0.011 16.1 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin-like domain USP7_ICP0_bdg PF12436.6 001266806.1_29622001_3 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 UN_NPL4 PF11543.6 001266806.1_29622001_3 - 0.023 15.0 0.0 1.3 9.4 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 DUF2407 PF10302.7 001266806.1_29622001_3 - 0.028 14.9 0.0 0.48 10.9 0.0 2.0 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain LRIF1 PF15741.3 001266807.1_29626001_3 - 0 1111.6 46.9 0 1111.4 46.9 1.0 1 0 0 1 1 1 1 Ligand-dependent nuclear receptor-interacting factor 1 Prismane PF03063.18 001266807.1_29626001_3 - 0.043 12.4 1.3 0.12 10.9 0.0 2.1 2 0 0 2 2 2 0 Prismane/CO dehydrogenase family PKcGMP_CC PF16808.3 001266807.1_29626001_3 - 0.57 10.0 6.5 1 9.1 6.5 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NIF PF03031.16 001266809.1_29627001_1 - 5.5e-55 185.3 1.0 9.4e-55 184.5 1.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Transthyretin PF00576.19 001261679.1_29622001_3 - 1.9e-19 70.2 0.0 2.7e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family zf-C2H2 PF00096.24 001266828.1_29628001_1 - 7.6e-13 48.0 21.9 9.3e-05 22.5 1.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001266828.1_29628001_1 - 1.1e-11 44.4 9.1 3.1e-08 33.6 2.6 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001266828.1_29628001_1 - 1.4e-05 25.4 30.4 0.00054 20.4 2.8 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001266828.1_29628001_1 - 0.009 15.8 2.4 0.009 15.8 2.4 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001266828.1_29628001_1 - 0.12 12.5 5.8 0.069 13.3 3.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.6 001266828.1_29628001_1 - 2.6 8.3 8.1 5.8 7.2 1.2 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.23 001258204.1_29624001_1 - 1.7e-67 227.4 0.0 2.2e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001258204.1_29624001_1 - 7.3e-33 113.8 0.0 1.1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001258204.1_29624001_1 - 1.9e-07 30.6 0.0 3.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001258204.1_29624001_1 - 0.15 11.8 0.1 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.22 001266841.2_29623001_2 - 4.2e-46 157.0 0.4 5.1e-46 156.8 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DSBA PF01323.18 001266849.1_29623001_1 - 2.6e-58 196.8 0.0 3.3e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Helicase_C_3 PF13625.4 001266849.1_29623001_1 - 0.094 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain EAL PF00563.18 001266849.1_29623001_1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 EAL domain Exo_endo_phos PF03372.21 001266860.1_29624001_1 - 2.1e-09 37.5 0.0 3.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tetraspannin PF00335.18 001266860.1_29624001_1 - 0.045 13.5 1.8 3.8 7.1 0.7 2.1 2 0 0 2 2 2 0 Tetraspanin family TRAM_LAG1_CLN8 PF03798.14 001260535.1_29626001_1 - 2.5e-25 89.3 13.8 5.8e-25 88.1 13.8 1.7 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.9 001260535.1_29626001_1 - 5.3e-19 67.5 0.6 1.2e-18 66.4 0.6 1.6 1 0 0 1 1 1 1 TRAM1-like protein PKD_channel PF08016.10 001260540.1_29624001_2 - 4.2e-10 38.8 13.2 6.3e-10 38.2 13.2 1.2 1 0 0 1 1 1 1 Polycystin cation channel DUF1866 PF08952.9 001260540.1_29624001_2 - 0.036 13.8 0.2 0.67 9.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) Ion_trans PF00520.29 001260540.1_29624001_2 - 0.054 12.6 22.8 0.14 11.2 22.9 1.6 1 1 0 1 1 1 0 Ion transport protein Glyco_transf_8 PF01501.18 001260544.1_29623001_3 - 1.2e-47 162.5 0.0 1.5e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 WD40_3 PF15911.3 001266872.1_29629001_2 - 1.3e-28 98.6 0.2 4.4e-28 97.0 0.2 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Clathrin PF00637.18 001266872.1_29629001_2 - 3.3e-11 43.1 4.9 0.0011 18.7 0.0 5.2 3 2 1 5 5 5 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.5 001266872.1_29629001_2 - 1.8e-10 40.9 1.3 0.0066 16.6 0.3 6.2 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.12 001266872.1_29629001_2 - 9.4e-08 31.4 3.7 0.037 13.0 0.1 3.8 4 0 0 4 4 4 3 Coatomer WD associated region ANAPC3 PF12895.5 001266872.1_29629001_2 - 0.00013 22.0 4.4 1.2 9.2 0.2 5.5 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.4 001266872.1_29629001_2 - 0.0003 21.1 6.2 12 6.4 0.0 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.30 001266872.1_29629001_2 - 0.00037 21.1 2.4 7 7.6 0.0 5.9 5 0 0 5 5 5 1 WD domain, G-beta repeat eIF2A PF08662.9 001266872.1_29629001_2 - 0.0013 18.5 0.1 0.0045 16.8 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A TPR_14 PF13428.4 001266872.1_29629001_2 - 0.0026 18.3 14.0 6.9 7.7 0.1 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.5 001266872.1_29629001_2 - 0.095 11.5 1.2 0.19 10.6 0.1 1.9 2 0 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PA-IIL PF07472.9 001266872.1_29629001_2 - 0.13 12.4 0.1 0.51 10.5 0.1 2.0 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) TPR_8 PF13181.4 001266872.1_29629001_2 - 0.21 11.7 18.7 17 5.8 0.7 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.26 001266872.1_29629001_2 - 0.25 11.1 24.6 1.9 8.3 1.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat zf-ribbon_3 PF13248.4 001266872.1_29629001_2 - 0.37 10.1 8.2 0.35 10.2 0.1 3.1 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.5 001266872.1_29629001_2 - 0.65 9.9 11.0 23 5.0 11.0 2.6 1 1 0 1 1 1 0 Double zinc ribbon SNAP PF14938.4 001266872.1_29629001_2 - 3.2 7.0 13.9 0.26 10.5 2.0 3.7 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP ParA PF10609.7 001266874.2_29623001_2 - 8.3e-97 323.3 0.0 9.5e-97 323.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.21 001266874.2_29623001_2 - 3.3e-13 49.7 0.0 6e-10 39.1 0.0 2.3 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.9 001266874.2_29623001_2 - 1e-08 34.7 0.0 2.6e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.4 001266874.2_29623001_2 - 1.5e-08 34.6 0.0 3.5e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.13 001266874.2_29623001_2 - 5.6e-07 29.0 1.1 5.7e-06 25.6 0.2 2.5 2 1 0 3 3 3 1 Anion-transporting ATPase ArgK PF03308.14 001266874.2_29623001_2 - 3e-05 23.0 0.2 5e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 ArgK protein AAA_26 PF13500.4 001266874.2_29623001_2 - 4.6e-05 23.2 0.2 0.1 12.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain Fer4_NifH PF00142.16 001266874.2_29623001_2 - 7.8e-05 22.1 0.0 0.0015 17.9 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.10 001266874.2_29623001_2 - 0.00066 19.1 0.0 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.18 001266874.2_29623001_2 - 0.0079 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.4 001266874.2_29623001_2 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.20 001266874.2_29623001_2 - 0.034 13.6 0.1 0.11 12.0 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CLP1_P PF16575.3 001266874.2_29623001_2 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.20 001266874.2_29623001_2 - 0.18 10.7 0.3 0.26 10.1 0.3 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.4 001266874.2_29623001_2 - 0.18 12.2 0.1 0.4 11.0 0.1 1.6 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.4 001266874.2_29623001_2 - 0.19 11.9 0.3 0.32 11.2 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.8 001266874.2_29623001_2 - 0.2 10.9 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.4 001266874.2_29623001_2 - 0.2 11.2 0.1 0.39 10.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.10 001266874.2_29623001_2 - 0.23 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.14 001266874.2_29623001_2 - 0.24 11.2 0.8 0.45 10.3 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 TPR_11 PF13414.4 001261730.2_29626001_1 - 8.1e-11 41.3 12.9 0.0019 17.7 0.2 5.6 5 0 0 5 5 5 4 TPR repeat TPR_2 PF07719.15 001261730.2_29626001_1 - 1.7e-09 36.9 27.0 0.0042 17.0 0.2 8.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.4 001261730.2_29626001_1 - 3.2e-09 36.8 11.8 5.4e-05 23.3 0.7 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.4 001261730.2_29626001_1 - 5.9e-09 36.2 17.5 0.00037 20.8 0.1 6.2 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.4 001261730.2_29626001_1 - 2e-08 34.2 9.6 0.0095 16.6 0.1 7.4 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.4 001261730.2_29626001_1 - 3.7e-07 29.9 17.0 0.13 12.6 0.2 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.26 001261730.2_29626001_1 - 4.1e-07 29.4 32.8 0.022 14.4 0.6 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.4 001261730.2_29626001_1 - 1.4e-06 27.9 24.7 0.032 14.3 0.7 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.4 001261730.2_29626001_1 - 0.0017 18.1 5.2 0.063 13.2 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.4 001261730.2_29626001_1 - 0.0062 15.6 0.5 0.21 10.6 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.4 001261730.2_29626001_1 - 0.014 15.9 2.7 4.7 7.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I_2 PF17014.3 001261730.2_29626001_1 - 0.13 12.3 1.7 1.5 8.8 0.8 2.6 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein TPR_10 PF13374.4 001261730.2_29626001_1 - 0.2 11.5 3.6 50 3.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001261730.2_29626001_1 - 1.1 9.4 13.9 3.2 7.9 0.0 5.0 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.4 001261730.2_29626001_1 - 1.1 9.9 10.0 7.3 7.3 0.1 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.16 001261730.2_29626001_1 - 4.3 7.4 7.6 12 6.0 0.3 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain zf-H2C2_2 PF13465.4 001266894.1_29625001_3 - 2.3e-13 49.8 18.7 1.7e-07 31.2 0.2 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.24 001266894.1_29625001_3 - 5.8e-10 39.0 26.0 8.3e-05 22.7 2.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001266894.1_29625001_3 - 1.4e-06 28.5 27.2 0.0088 16.7 2.9 4.3 3 0 0 3 3 3 3 C2H2-type zinc finger MPC PF03650.11 001260570.1_29621001_2 - 6.9e-34 116.2 0.2 8.9e-34 115.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) BAR_3_WASP_bdg PF10456.7 001261750.1_29625001_1 - 9.9e-108 358.9 6.5 1.4e-107 358.4 6.5 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.22 001261750.1_29625001_1 - 4.7e-22 78.0 0.2 1e-21 76.9 0.2 1.6 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.4 001261750.1_29625001_1 - 4.9e-11 42.2 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.15 001261750.1_29625001_1 - 2.2e-10 39.9 0.1 8.4e-10 38.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.26 001261750.1_29625001_1 - 3e-09 36.2 0.0 9.2e-09 34.7 0.0 1.9 1 0 0 1 1 1 1 SH3 domain Vps5 PF09325.8 001261750.1_29625001_1 - 0.0077 15.7 2.3 0.0077 15.7 2.3 2.2 2 0 0 2 2 2 1 Vps5 C terminal like BAR PF03114.16 001261750.1_29625001_1 - 0.034 13.7 2.3 0.061 12.8 2.3 1.4 1 0 0 1 1 1 0 BAR domain MHC_I PF00129.16 001260576.2_29625001_3 - 3.4e-41 140.6 0.5 4.9e-41 140.1 0.5 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001260576.2_29625001_3 - 7e-14 51.9 0.1 1.8e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_3 PF16497.3 001260576.2_29625001_3 - 5.3e-09 35.7 0.3 8.1e-09 35.1 0.3 1.2 1 0 0 1 1 1 1 MHC-I family domain Ig_2 PF13895.4 001260576.2_29625001_3 - 0.0043 17.2 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain DUF912 PF06024.10 001260576.2_29625001_3 - 0.04 14.1 0.3 0.081 13.1 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ig PF00047.23 001260576.2_29625001_3 - 0.057 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain SKG6 PF08693.8 001260576.2_29625001_3 - 0.12 11.7 3.3 0.23 10.8 3.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.14 001260576.2_29625001_3 - 0.29 10.8 0.9 0.44 10.2 0.9 1.2 1 0 0 1 1 1 0 Rifin/stevor family Ssl1 PF04056.12 001260580.1_29623001_1 - 3.8e-95 317.1 0.1 5e-95 316.7 0.1 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.4 001260580.1_29623001_1 - 1.7e-12 47.8 0.0 4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.10 001260580.1_29623001_1 - 5e-11 42.6 27.8 3.8e-10 39.8 21.2 3.1 2 1 0 2 2 2 1 TFIIH C1-like domain VWA PF00092.26 001260580.1_29623001_1 - 1.1e-06 28.9 0.0 1.6e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.4 001260580.1_29623001_1 - 0.018 14.8 0.0 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain DZR PF12773.5 001260580.1_29623001_1 - 0.068 13.1 18.0 2.1 8.3 0.5 3.3 2 1 1 3 3 3 0 Double zinc ribbon IBR PF01485.19 001260580.1_29623001_1 - 2.1 8.5 19.0 0.64 10.2 10.0 3.1 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Chromo_shadow PF01393.17 001266912.1_29625001_1 - 2.7e-29 100.8 0.8 1.5e-26 92.0 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.22 001266912.1_29625001_1 - 2e-18 65.9 1.0 1e-16 60.4 0.8 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.4 001266912.1_29625001_1 - 0.026 14.6 0.2 0.055 13.5 0.2 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 ELO PF01151.16 001266921.1_29627001_3 - 7.2e-68 228.7 27.5 1.7e-67 227.5 27.5 1.6 1 0 0 1 1 1 1 GNS1/SUR4 family MAGE_N PF12440.6 001260599.1_29626001_3 - 7.5e-31 106.5 13.4 1.5e-30 105.6 13.4 1.5 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal MAGE PF01454.17 001260599.1_29626001_3 - 1.5e-14 54.1 0.0 3.1e-12 46.5 0.0 2.2 1 1 0 1 1 1 1 MAGE family zf-H2C2_2 PF13465.4 001266924.1_29626001_1 - 7.3e-12 45.0 10.7 1.6e-07 31.4 3.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.24 001266924.1_29626001_1 - 7e-11 41.8 33.4 3e-05 24.1 2.2 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001266924.1_29626001_1 - 1.5e-06 28.4 29.2 0.00047 20.6 1.7 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001266924.1_29626001_1 - 0.008 16.3 2.5 0.023 14.8 2.5 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.6 001266924.1_29626001_1 - 0.2 11.9 4.9 7.1 6.9 0.7 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.10 001266924.1_29626001_1 - 0.23 11.7 10.1 0.56 10.4 2.7 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding USP8_dimer PF08969.9 001260604.1_29625001_3 - 4.8e-21 74.9 0.2 4.8e-21 74.9 0.2 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain JAB PF01398.19 001260604.1_29625001_3 - 1.3e-20 73.4 0.0 1.3e-20 73.4 0.0 2.4 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.4 001260604.1_29625001_3 - 1e-06 28.4 0.0 2.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3526 PF12040.6 001260604.1_29625001_3 - 0.13 12.6 5.4 0.23 11.9 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) FAM176 PF14851.4 001260604.1_29625001_3 - 7.8 6.0 10.0 16 5.1 10.0 1.4 1 0 0 1 1 1 0 FAM176 family Sec61_beta PF03911.14 001266938.1_29622001_2 - 2.7e-19 68.8 0.0 5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Sec61beta family WD40 PF00400.30 001266941.1_29625001_3 - 6.6e-10 39.3 0.2 0.0021 18.7 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001266941.1_29625001_3 - 0.00012 22.2 0.2 0.055 13.6 0.2 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001266941.1_29625001_3 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RPA_C PF08784.9 001260634.1_29624001_2 - 2.4e-25 89.1 0.0 5e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.23 001260634.1_29624001_2 - 4.1e-05 23.4 0.0 6.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MarR_2 PF12802.5 001260634.1_29624001_2 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 MarR family RMI2 PF16100.3 001260634.1_29624001_2 - 0.16 11.6 0.2 12 5.6 0.0 2.2 1 1 1 2 2 2 0 RecQ-mediated genome instability protein 2 Jagunal PF07086.10 001260648.2_29624001_3 - 5.4e-67 225.4 7.3 7.3e-67 225.0 7.3 1.2 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis Kin17_mid PF10357.7 001261813.1_29625001_2 - 5.7e-50 168.3 2.0 5.7e-50 168.3 2.0 2.1 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KOW PF00467.27 001261813.1_29625001_2 - 0.013 15.3 0.6 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 KOW motif SecM PF06558.10 001261813.1_29625001_2 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) zf-met PF12874.5 001261813.1_29625001_2 - 0.15 12.3 8.5 0.39 11.0 8.5 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DDHD PF02862.15 001261813.1_29625001_2 - 0.16 12.0 3.8 0.25 11.3 3.8 1.2 1 0 0 1 1 1 0 DDHD domain zf-C2H2_jaz PF12171.6 001261813.1_29625001_2 - 0.69 10.2 8.8 1.7 9.0 8.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ABC_tran PF00005.25 001260653.1_29629001_2 - 4.9e-53 179.2 0.1 1e-30 106.9 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.21 001260653.1_29629001_2 - 9.9e-52 176.1 32.7 1.1e-34 120.2 9.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.17 001260653.1_29629001_2 - 9.2e-11 41.5 6.4 0.011 15.0 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.4 001260653.1_29629001_2 - 0.0002 20.9 2.2 0.42 10.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.21 001260653.1_29629001_2 - 0.00033 20.6 1.0 0.81 9.7 0.2 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.4 001260653.1_29629001_2 - 0.00033 21.1 0.8 0.17 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.4 001260653.1_29629001_2 - 0.0036 17.6 0.1 5.1 7.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.21 001260653.1_29629001_2 - 0.0045 16.9 1.2 0.082 12.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.14 001260653.1_29629001_2 - 0.0052 16.6 0.6 0.27 11.0 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.4 001260653.1_29629001_2 - 0.0067 16.1 10.7 2.9 7.5 0.1 4.0 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.4 001260653.1_29629001_2 - 0.017 14.7 0.2 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.10 001260653.1_29629001_2 - 0.046 12.9 1.0 2.3 7.3 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.4 001260653.1_29629001_2 - 0.053 13.9 0.1 9.4 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.20 001260653.1_29629001_2 - 0.061 12.2 0.3 2.4 7.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.15 001260653.1_29629001_2 - 0.065 12.9 0.5 2.7 7.6 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein T2SSE PF00437.18 001260653.1_29629001_2 - 0.088 11.7 0.0 4.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.17 001260653.1_29629001_2 - 0.096 12.1 1.9 0.15 11.5 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.15 001260653.1_29629001_2 - 0.2 11.5 0.7 0.54 10.1 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.15 001260653.1_29629001_2 - 0.23 11.3 4.2 2.1 8.2 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.4 001260653.1_29629001_2 - 1.9 8.6 5.0 20 5.3 0.2 3.2 2 1 0 2 2 2 0 AAA domain Mago_nashi PF02792.12 001265616.1_29622001_3 - 1.3e-79 265.1 0.2 1.6e-79 264.7 0.2 1.1 1 0 0 1 1 1 1 Mago nashi protein AIG2_2 PF13772.4 001266969.1_29623001_3 - 4.5e-28 97.3 0.1 6.5e-28 96.8 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.10 001266969.1_29623001_3 - 3.3e-09 37.2 0.0 5.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ChaC PF04752.10 001266969.1_29623001_3 - 0.079 12.9 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 ChaC-like protein COX7C PF02935.14 001260661.1_29623001_2 - 5.8 7.1 6.0 1.9 8.6 2.7 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Tetraspannin PF00335.18 001260661.1_29623001_3 - 6.3e-44 150.2 9.8 6.3e-44 150.2 9.8 1.8 2 0 0 2 2 2 1 Tetraspanin family DUF4064 PF13273.4 001260661.1_29623001_3 - 6.8 7.0 19.5 3.8 7.8 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) Cornichon PF03311.12 001260666.1_29622001_1 - 7.7e-49 164.9 9.7 9.3e-49 164.7 9.7 1.1 1 0 0 1 1 1 1 Cornichon protein LRR_8 PF13855.4 001260677.1_29623001_1 - 3.3e-36 122.7 25.2 7.9e-13 47.8 5.3 5.9 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.5 001260677.1_29623001_1 - 7.9e-24 83.1 26.9 8.4e-06 25.9 0.4 6.5 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001260677.1_29623001_1 - 1.2e-09 37.8 3.2 0.0085 15.5 0.0 4.1 1 1 3 4 4 4 3 Leucine-rich repeat LRRNT PF01462.16 001260677.1_29623001_1 - 7.4e-09 34.9 4.9 1.2e-08 34.3 2.5 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.4 001260677.1_29623001_1 - 2.5e-08 33.2 25.9 0.39 10.8 0.3 9.3 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.31 001260677.1_29623001_1 - 5.8e-08 32.0 25.9 0.38 11.3 0.2 9.2 7 2 2 9 9 9 4 Leucine Rich Repeat LRR_5 PF13306.4 001260677.1_29623001_1 - 1.2e-06 28.3 0.1 0.0074 16.1 0.0 3.0 2 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_2 PF07723.11 001260677.1_29623001_1 - 0.077 13.6 0.4 22 5.8 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat Coa1 PF08695.8 001265636.2_29622001_1 - 1.9e-22 79.1 0.0 2.5e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.9 001265636.2_29622001_1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 TIM21 Myotub-related PF06602.12 001266986.1_29627001_3 - 2.8e-57 194.1 7.1 2.1e-51 174.8 5.5 2.2 1 1 0 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.6 001266986.1_29627001_3 - 1.4e-38 131.5 1.1 2.5e-38 130.6 1.1 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein Abhydrolase_1 PF00561.18 001265641.1_29623001_1 - 4.6e-19 68.9 0.0 6.5e-19 68.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001265641.1_29623001_1 - 2.2e-17 64.3 0.2 3.1e-17 63.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001265641.1_29623001_1 - 2.1e-10 40.2 0.0 3.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.12 001265641.1_29623001_1 - 0.003 16.2 0.0 0.0084 14.7 0.0 1.6 2 0 0 2 2 2 1 Ndr family DUF2251 PF10008.7 001265641.1_29623001_1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2251) WD40 PF00400.30 001265643.1_29628001_1 - 1.3e-55 183.9 19.1 6.2e-09 36.2 0.2 10.8 10 0 0 10 10 10 10 WD domain, G-beta repeat Utp12 PF04003.10 001265643.1_29628001_1 - 1.7e-22 79.6 0.0 3.4e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.5 001265643.1_29628001_1 - 1.6e-20 73.0 2.5 4.6e-05 23.5 0.0 8.5 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.3 001265643.1_29628001_1 - 1.7e-08 34.1 0.0 0.01 15.0 0.0 3.7 3 0 0 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.3 001265643.1_29628001_1 - 4.1e-06 25.9 1.4 11 4.8 0.0 6.4 3 1 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.9 001265643.1_29628001_1 - 0.00049 18.9 0.3 11 4.5 0.0 4.7 4 1 0 4 4 4 2 Nup133 N terminal like Utp21 PF04192.10 001265643.1_29628001_1 - 0.013 14.9 0.8 0.084 12.3 0.0 2.2 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Coatomer_WDAD PF04053.12 001265643.1_29628001_1 - 0.017 14.0 0.0 0.16 10.8 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region YbaB_DNA_bd PF02575.14 001265643.1_29628001_1 - 0.039 14.1 1.0 0.11 12.6 1.0 1.7 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Peptidase_C15 PF01470.15 001260688.1_29623001_1 - 1.7e-19 70.5 0.0 2.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Img2 PF05046.12 001266995.2_29622001_2 - 8.8e-28 96.3 0.0 1.1e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Dynactin_p22 PF07426.9 001265650.1_29622001_3 - 6.8e-58 195.1 1.1 8.2e-58 194.8 1.1 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 DUF4011 PF13195.4 001265650.1_29622001_3 - 0.0056 16.5 0.6 0.0092 15.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4011) Spidroin_MaSp PF11260.6 001265650.1_29622001_3 - 0.025 14.8 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 DUF948 PF06103.9 001265650.1_29622001_3 - 0.048 13.8 0.3 2.6 8.2 0.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CHDCT2 PF08074.9 001265650.1_29622001_3 - 0.12 12.4 1.0 0.21 11.6 1.0 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DivIC PF04977.13 001265650.1_29622001_3 - 0.23 11.1 6.8 0.47 10.1 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator BolA PF01722.16 001265651.1_29621001_3 - 2.3e-11 43.7 0.1 3.8e-11 43.0 0.1 1.4 1 1 0 1 1 1 1 BolA-like protein RNA_binding PF01877.15 001265651.1_29621001_3 - 0.064 13.4 0.4 0.086 13.0 0.4 1.1 1 0 0 1 1 1 0 RNA binding Glucokinase PF02685.14 001265651.1_29621001_3 - 0.085 11.7 0.1 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 Glucokinase Endonuclease_NS PF01223.21 001260700.1_29625001_3 - 6.7e-06 26.0 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Homeobox PF00046.27 001267014.1_29629001_3 - 8.3e-34 115.1 14.9 3.3e-07 29.9 0.0 5.4 5 0 0 5 5 5 5 Homeobox domain Homez PF11569.6 001267014.1_29629001_3 - 6.9e-20 70.1 6.3 1.6e-11 43.3 0.3 5.4 5 0 0 5 5 5 5 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.9 001267014.1_29629001_3 - 3.9e-17 61.7 9.1 0.00089 19.0 0.1 5.6 5 0 0 5 5 5 5 Homeobox KN domain Cpn60_TCP1 PF00118.22 001267014.1_29629001_3 - 0.13 10.7 0.7 0.19 10.1 0.7 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family PCMT PF01135.17 001260718.1_29624001_1 - 1.8e-29 102.9 0.0 2.5e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.14 001260718.1_29624001_1 - 7.4e-06 26.1 2.7 0.022 15.0 1.2 2.5 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.11 001260718.1_29624001_1 - 0.0005 19.5 0.0 0.00093 18.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.4 001260718.1_29624001_1 - 0.003 17.2 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.8 001260718.1_29624001_1 - 0.0073 15.9 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.4 001260718.1_29624001_1 - 0.018 15.6 0.0 0.041 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.10 001260718.1_29624001_1 - 0.1 13.2 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SIT PF15330.4 001267025.1_29623001_1 - 0.0042 17.4 0.0 0.029 14.6 0.0 2.1 1 1 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT Pet191_N PF10203.7 001267542.1_29624001_1 - 1.2e-19 70.2 2.9 2e-19 69.5 2.9 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 HECT PF00632.23 001267601.1_29629001_1 - 2.1e-98 329.4 0.3 2.9e-98 329.0 0.3 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.24 001267601.1_29629001_1 - 3.7e-45 151.4 38.7 1.5e-12 47.1 5.0 4.9 5 0 0 5 5 5 4 WW domain THRAP3_BCLAF1 PF15440.4 001265696.1_29627001_3 - 1.1e-209 698.7 105.4 1.1e-209 698.7 105.4 2.6 3 0 0 3 3 3 1 THRAP3/BCLAF1 family Abhydrolase_1 PF00561.18 001260756.1_29625001_1 - 1.6e-23 83.5 0.0 4.8e-23 82.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001260756.1_29625001_1 - 1.8e-18 67.8 0.6 3.3e-18 67.0 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001260756.1_29625001_1 - 5.6e-12 45.3 0.0 9.5e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.11 001260756.1_29625001_1 - 9.3e-05 21.0 0.0 0.0028 16.1 0.0 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Ndr PF03096.12 001260756.1_29625001_1 - 0.0049 15.5 0.0 0.011 14.3 0.0 1.5 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.9 001260756.1_29625001_1 - 0.061 12.5 0.0 0.73 9.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.18 001260756.1_29625001_1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.11 001260756.1_29625001_1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein TFIID-31kDa PF02291.13 001260763.1_29623001_1 - 6.6e-51 171.3 0.0 1e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.4 001260763.1_29623001_1 - 2.1e-06 27.9 0.1 4.3e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein AAA_18 PF13238.4 001260763.1_29623001_1 - 6.4e-05 23.3 0.2 0.00014 22.2 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.4 001260763.1_29623001_1 - 6.5e-05 23.2 0.1 6.5e-05 23.2 0.1 1.8 2 0 0 2 2 1 1 AAA domain Bromo_TP PF07524.11 001260763.1_29623001_1 - 8.5e-05 22.4 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.22 001260763.1_29623001_1 - 0.00025 21.3 0.3 0.00051 20.3 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001260763.1_29623001_1 - 0.0031 17.5 0.1 0.0057 16.6 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA PF00004.27 001260763.1_29623001_1 - 0.0078 16.5 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.20 001260763.1_29623001_1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.4 001260763.1_29623001_1 - 0.032 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ADK PF00406.20 001260763.1_29623001_1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Adenylate kinase AAA_33 PF13671.4 001260763.1_29623001_1 - 0.077 13.0 0.4 0.33 11.0 0.4 2.1 1 1 0 1 1 1 0 AAA domain CBFD_NFYB_HMF PF00808.21 001260763.1_29623001_1 - 0.12 12.6 0.1 0.32 11.2 0.1 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TM2 PF05154.14 001260764.1_29623001_2 - 1.2e-14 54.3 12.2 2.2e-14 53.4 12.2 1.5 1 0 0 1 1 1 1 TM2 domain 3Beta_HSD PF01073.17 001265710.1_29623001_1 - 1.6e-62 211.0 0.0 2.1e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.19 001265710.1_29623001_1 - 1.1e-33 116.6 0.0 1.4e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001265710.1_29623001_1 - 1.1e-16 61.0 0.0 1.7e-15 57.1 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.4 001265710.1_29623001_1 - 8.6e-16 58.3 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.15 001265710.1_29623001_1 - 4.9e-11 42.1 0.0 6.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.10 001265710.1_29623001_1 - 4.2e-09 35.8 0.0 0.00018 20.6 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.13 001265710.1_29623001_1 - 1.6e-08 34.0 0.0 1.8e-07 30.4 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.11 001265710.1_29623001_1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.13 001265710.1_29623001_1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SAM_2 PF07647.15 001265713.1_29627001_2 - 9e-30 102.5 0.1 6.9e-15 54.8 0.1 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001265713.1_29627001_2 - 4e-18 65.5 0.1 7.8e-14 51.7 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.4 001265713.1_29627001_2 - 2.2e-17 63.1 0.0 6.2e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 TIR domain SAM_PNT PF02198.14 001265713.1_29627001_2 - 0.038 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain HEAT_2 PF13646.4 001265713.1_29627001_2 - 0.096 12.9 9.6 0.62 10.3 0.3 3.9 3 2 1 4 4 4 0 HEAT repeats Arm PF00514.21 001265713.1_29627001_2 - 5.8 7.0 8.4 0.76 9.8 0.4 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Ras PF00071.20 001260776.1_29623001_1 - 1.9e-49 167.2 0.0 2.4e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001260776.1_29623001_1 - 1.9e-30 105.4 0.0 3.4e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001260776.1_29623001_1 - 3.2e-11 42.9 0.0 4.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001260776.1_29623001_1 - 0.00031 20.7 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.20 001260776.1_29623001_1 - 0.00087 19.5 0.1 0.0027 17.9 0.1 1.8 1 1 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.25 001260776.1_29623001_1 - 0.003 17.0 0.4 0.01 15.3 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.10 001260776.1_29623001_1 - 0.0036 16.5 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.18 001260776.1_29623001_1 - 0.016 14.3 1.1 0.81 8.6 0.0 2.7 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.10 001260776.1_29623001_1 - 0.024 14.0 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.8 001260776.1_29623001_1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.4 001260776.1_29623001_1 - 0.028 14.0 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ArgoMid PF16487.3 001260776.1_29623001_1 - 0.062 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute TsaE PF02367.15 001260776.1_29623001_1 - 0.072 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.4 001260776.1_29623001_1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.16 001260776.1_29623001_1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_33 PF13671.4 001260776.1_29623001_1 - 0.2 11.7 0.2 0.33 11.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain Gal-3-0_sulfotr PF06990.9 001260777.1_29624001_3 - 6.4e-108 361.1 1.9 5.6e-55 186.7 0.1 2.0 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Ras PF00071.20 001265717.1_29622001_1 - 7.7e-50 168.5 0.0 1e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001265717.1_29622001_1 - 9.4e-21 74.1 0.0 1.7e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001265717.1_29622001_1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Lipase_GDSL_3 PF14606.4 001265717.1_29622001_1 - 0.018 15.1 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AAA_16 PF13191.4 001265717.1_29622001_1 - 0.12 12.6 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SLBP_RNA_bind PF15247.4 001265717.1_29622001_1 - 0.2 11.6 2.4 0.26 11.3 0.7 1.9 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain DBC1 PF14443.4 001260782.1_29628001_1 - 1.1e-51 173.9 0.0 5.5e-51 171.6 0.0 2.4 1 0 0 1 1 1 1 DBC1 S1-like PF14444.4 001260782.1_29628001_1 - 2.2e-32 110.8 0.8 3.9e-32 110.0 0.8 1.4 1 0 0 1 1 1 1 S1-like SAP PF02037.25 001260782.1_29628001_1 - 4.2e-09 35.8 1.7 4.2e-09 35.8 1.7 2.3 2 0 0 2 2 2 1 SAP domain Tautomerase_2 PF14552.4 001260782.1_29628001_1 - 0.028 14.4 0.1 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 Tautomerase enzyme Cyclin_N PF00134.21 001278446.1_29629001_1 - 3.3e-37 127.0 2.2 6e-37 126.2 2.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001278446.1_29629001_1 - 3.8e-20 72.0 0.3 1.6e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain COesterase PF00135.26 001168494.1_29624001_1 - 2.8e-136 455.3 0.0 2.5e-114 382.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.11 001168494.1_29624001_1 - 2.3e-07 30.8 0.1 8.3e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001168494.1_29624001_1 - 0.00029 20.2 0.1 0.00053 19.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DSPc PF00782.18 001265730.1_29624001_1 - 6.3e-43 145.6 0.0 8.1e-43 145.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.18 001265730.1_29624001_1 - 1.4e-06 28.6 0.0 3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Init_tRNA_PT PF04179.10 001265730.1_29624001_1 - 0.0018 18.4 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.25 001265730.1_29624001_1 - 0.0028 17.1 0.0 0.0041 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.4 001265730.1_29624001_1 - 0.02 14.9 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.10 001265730.1_29624001_1 - 0.088 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.11 001265730.1_29624001_1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-C2H2_4 PF13894.4 001260800.1_29626001_2 - 0.012 16.2 0.1 0.012 16.2 0.1 5.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_5 PF13909.4 001260800.1_29626001_2 - 0.035 13.7 0.0 0.035 13.7 0.0 4.7 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.24 001260800.1_29626001_2 - 0.21 12.0 0.1 0.21 12.0 0.1 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type Lipocalin PF00061.21 001171840.1_29622001_1 - 1.8e-11 44.3 0.0 2.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SecE PF00584.18 001265733.1_29621001_2 - 1.3e-14 53.6 0.1 2.2e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ribosomal_L29 PF00831.21 001265735.1_29621001_1 - 1.9e-20 72.4 2.2 1.9e-20 72.4 2.2 2.4 2 1 1 3 3 3 1 Ribosomal L29 protein Inhibitor_Mig-6 PF11555.6 001265738.1_29624001_1 - 0.041 13.9 0.4 0.041 13.9 0.4 1.8 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 CRAL_TRIO PF00650.18 001265738.1_29624001_3 - 5.8e-34 117.0 0.0 1.1e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.4 001265738.1_29624001_3 - 2.2e-07 30.9 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.13 001265738.1_29624001_3 - 5.7e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Abhydrolase_6 PF12697.5 001171865.1_29622001_3 - 1.4e-11 45.3 3.8 8.4e-07 29.7 2.8 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001171865.1_29622001_3 - 4.2e-11 42.8 0.0 8.1e-05 22.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001171865.1_29622001_3 - 1.7e-06 27.3 0.1 0.00036 19.8 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 PGPGW PF09656.8 001171865.1_29622001_3 - 0.046 13.1 0.3 0.52 9.7 0.1 2.3 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) DLH PF01738.16 001171865.1_29622001_3 - 0.069 12.6 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Integrin_alpha2 PF08441.10 001260822.1_29628001_1 - 3.3e-49 167.9 7.6 5e-49 167.3 7.6 1.2 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.26 001260822.1_29628001_1 - 6.2e-40 137.2 0.2 1.2e-39 136.2 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.21 001260822.1_29628001_1 - 2.3e-20 72.3 3.6 1.5e-08 34.5 0.3 3.8 3 0 0 3 3 3 3 FG-GAP repeat VWA_2 PF13519.4 001260822.1_29628001_1 - 7.6e-14 52.2 0.0 1.8e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP_2 PF14312.4 001260822.1_29628001_1 - 2e-07 31.0 3.9 0.088 12.9 0.0 5.2 5 0 0 5 5 5 2 FG-GAP repeat VCBS PF13517.4 001260822.1_29628001_1 - 3.5e-06 27.4 9.5 0.00034 21.0 1.8 4.0 4 0 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001260822.1_29628001_1 - 0.0015 18.2 2.2 0.0035 17.1 2.2 1.7 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LSM PF01423.20 001260829.1_29624001_1 - 6e-18 64.2 0.7 9.2e-18 63.6 0.7 1.3 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.6 001260829.1_29624001_1 - 0.0059 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) Hfq PF17209.1 001260829.1_29624001_1 - 0.042 13.4 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Hfq protein DUF4512 PF14975.4 001190838.1_29622001_1 - 8.6e-17 61.6 2.1 1.2e-16 61.2 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Rgp1 PF08737.8 001265774.2_29624001_1 - 2e-45 155.6 0.0 7e-23 81.3 0.0 2.2 2 0 0 2 2 2 2 Rgp1 bZIP_2 PF07716.13 001190861.2_29624001_2 - 7.3e-11 41.8 14.3 7.3e-11 41.8 14.3 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.19 001190861.2_29624001_2 - 7.9e-10 38.6 13.9 1.2e-09 37.9 13.0 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.15 001190861.2_29624001_2 - 5.4e-06 26.7 11.6 1e-05 25.8 11.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor KASH_CCD PF14662.4 001190861.2_29624001_2 - 0.002 17.9 8.1 0.0035 17.1 8.1 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HOOK PF05622.10 001190861.2_29624001_2 - 0.0068 14.5 6.6 0.0093 14.0 6.6 1.1 1 0 0 1 1 1 1 HOOK protein DUF972 PF06156.11 001190861.2_29624001_2 - 0.032 14.7 9.1 0.43 11.1 8.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.16 001190861.2_29624001_2 - 0.24 11.6 4.9 1.1 9.5 4.9 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family FtsL PF04999.11 001190861.2_29624001_2 - 0.26 11.2 2.1 0.5 10.2 2.1 1.4 1 0 0 1 1 1 0 Cell division protein FtsL Atg14 PF10186.7 001190861.2_29624001_2 - 5.3 5.9 8.8 7.6 5.4 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med10 PF09748.7 001260853.1_29623001_1 - 4.1e-36 123.5 0.3 5.2e-36 123.1 0.3 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Sigma70_r1_1 PF03979.12 001260853.1_29623001_1 - 0.14 12.1 1.0 15 5.6 0.1 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Complex1_LYR PF05347.13 001265787.1_29622001_3 - 1.6e-17 63.1 0.4 2.4e-17 62.6 0.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.4 001265787.1_29622001_3 - 1.2e-05 25.9 0.1 1.6e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.4 001265787.1_29622001_3 - 0.0062 17.0 0.1 0.0085 16.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Romo1 PF10247.7 001190916.1_29621001_3 - 2.1e-25 88.7 20.9 2.6e-25 88.4 20.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.17 001190916.1_29621001_3 - 0.0036 17.5 8.2 0.0043 17.2 8.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TRIQK PF15168.4 001265814.1_29622001_1 - 8.7e-39 131.2 0.8 1.5e-38 130.4 0.8 1.4 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family Ribosomal_L27e PF01777.16 001265822.1_29622001_2 - 1.8e-39 133.9 8.9 2.7e-39 133.3 8.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.27 001265822.1_29622001_2 - 6e-06 25.9 0.1 1.3e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 KOW motif MAGE PF01454.17 001265825.1_29624001_2 - 3.2e-06 26.9 0.0 0.00044 19.9 0.0 2.2 1 1 1 2 2 2 2 MAGE family SPX PF03105.17 001265825.1_29624001_2 - 0.084 12.7 3.9 0.12 12.2 3.9 1.1 1 0 0 1 1 1 0 SPX domain MAGE_N PF12440.6 001265825.1_29624001_2 - 1.7 9.2 29.0 5.2 7.7 26.3 2.7 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal UPF0731 PF14982.4 001265827.1_29622001_2 - 1.4e-14 53.9 0.5 2.8e-14 52.9 0.5 1.5 1 0 0 1 1 1 1 UPF0731 family WD40 PF00400.30 001265839.1_29624001_3 - 2.7e-19 69.0 13.0 9.7e-07 29.3 0.0 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat Nucleoporin_N PF08801.9 001265839.1_29624001_3 - 0.033 12.8 0.3 1.3 7.5 0.3 2.4 2 1 0 2 2 2 0 Nup133 N terminal like ANAPC4_WD40 PF12894.5 001265839.1_29624001_3 - 0.085 13.0 0.0 37 4.6 0.0 3.5 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain FGF PF00167.16 001265843.1_29625001_1 - 7e-42 142.3 0.2 1.1e-41 141.7 0.2 1.3 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 001265843.1_29625001_1 - 0.021 14.9 0.0 0.069 13.2 0.0 1.8 2 0 0 2 2 2 0 Fascin domain GRP PF07172.9 001265843.1_29625001_3 - 0.14 12.7 3.9 0.27 11.8 3.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family MHC_II_alpha PF00993.18 001193474.1_29622001_3 - 2.4e-20 71.9 0.1 3.4e-20 71.4 0.1 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set PF07654.13 001193474.1_29622001_3 - 6.4e-14 52.1 0.0 9.8e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C1-set_C PF16196.3 001193474.1_29622001_3 - 5.3e-07 28.8 0.2 1.1e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 C1-set C-terminal domain SKG6 PF08693.8 001193474.1_29622001_3 - 0.012 14.8 3.6 0.021 14.1 3.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pyridox_oxidase PF01243.18 001265856.1_29624001_2 - 3.2e-25 88.0 0.0 5.5e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.7 001265856.1_29624001_2 - 5.1e-17 61.5 1.0 9.8e-17 60.6 1.0 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.5 001265856.1_29624001_2 - 1.9e-06 28.2 0.0 3.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MHC_I PF00129.16 001318347.1_29623001_1 - 4.6e-93 309.6 0.7 6.7e-93 309.1 0.7 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001318347.1_29623001_1 - 1.1e-17 64.1 0.0 2.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001318347.1_29623001_1 - 2.3e-12 46.4 11.9 5e-12 45.4 11.9 1.6 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001318347.1_29623001_1 - 2.5e-06 27.9 1.0 0.015 15.8 0.0 2.9 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 001318347.1_29623001_1 - 7.6e-05 22.6 1.4 0.00016 21.5 0.2 2.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001318347.1_29623001_1 - 0.00086 19.3 0.2 0.003 17.5 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain DUF202 PF02656.13 001318347.1_29623001_1 - 0.072 13.4 0.1 9.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Histone PF00125.22 001193550.1_29622001_3 - 1.4e-18 67.4 0.0 2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.3 001193550.1_29622001_3 - 1.5e-12 46.9 0.5 2.7e-12 46.1 0.5 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.21 001193550.1_29622001_3 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sec7 PF01369.18 001265874.1_29623001_2 - 6.1e-36 123.7 0.1 9e-36 123.2 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.5 001265874.1_29623001_2 - 6.9e-07 28.9 0.5 1.5e-06 27.8 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001265874.1_29623001_2 - 0.0084 15.8 1.3 0.012 15.3 0.2 1.9 2 0 0 2 2 2 1 F-box domain Ribosomal_S13_N PF08069.10 001265917.1_29622001_3 - 6.3e-33 112.5 0.1 1.1e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.20 001265917.1_29622001_3 - 9.6e-16 57.6 1.3 1.5e-15 57.0 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.16 001265917.1_29622001_3 - 0.047 13.5 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain MAGE_N PF12440.6 001265924.1_29623001_1 - 3.9e-26 91.4 13.2 9.6e-26 90.2 13.2 1.7 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal MAGE PF01454.17 001265924.1_29623001_1 - 5.2e-15 55.6 0.0 1.2e-08 34.8 0.0 2.2 1 1 1 2 2 2 2 MAGE family DUF3098 PF11297.6 001265924.1_29623001_1 - 0.023 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) UPF0172 PF03665.11 001265927.1_29624001_3 - 4e-64 216.0 0.0 4.9e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) MMtag PF10159.7 001265942.2_29623001_3 - 1.4e-30 105.3 0.2 1.4e-30 105.3 0.2 2.4 2 0 0 2 2 1 1 Kinase phosphorylation protein GAGA_bind PF06217.10 001265942.2_29623001_3 - 0.0012 19.1 4.2 0.0016 18.6 4.2 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family RNA_polI_A34 PF08208.9 001265942.2_29623001_3 - 0.0099 15.9 17.7 0.017 15.1 17.7 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF3987 PF13148.4 001265942.2_29623001_3 - 0.05 12.4 3.2 0.074 11.9 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF936 PF06075.10 001265942.2_29623001_3 - 0.05 12.4 12.2 0.062 12.1 12.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SRP-alpha_N PF04086.11 001265942.2_29623001_3 - 0.06 13.1 14.0 0.084 12.6 14.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Coilin_N PF15862.3 001265942.2_29623001_3 - 0.099 12.3 12.5 0.17 11.6 12.5 1.3 1 0 0 1 1 1 0 Coilin N-terminus Zip PF02535.20 001265942.2_29623001_3 - 0.1 11.7 4.2 0.12 11.4 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.9 001265942.2_29623001_3 - 0.11 11.8 8.6 0.19 11.0 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_Rpc4 PF05132.12 001265942.2_29623001_3 - 0.14 12.5 7.0 0.21 11.9 7.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.10 001265942.2_29623001_3 - 0.16 11.6 11.9 0.23 11.1 11.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MIP-T3 PF10243.7 001265942.2_29623001_3 - 0.24 9.9 19.7 0.29 9.7 19.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SAPS PF04499.13 001265942.2_29623001_3 - 0.41 9.2 5.4 0.54 8.8 5.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CPSF100_C PF13299.4 001265942.2_29623001_3 - 0.57 10.2 6.1 0.98 9.5 6.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.14 001265942.2_29623001_3 - 1.1 9.1 5.5 1.6 8.6 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med19 PF10278.7 001265942.2_29623001_3 - 1.4 8.7 19.8 2.3 8.0 19.8 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AP3D1 PF06375.9 001265942.2_29623001_3 - 1.5 9.0 20.6 2.8 8.1 20.6 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Tim54 PF11711.6 001265942.2_29623001_3 - 2.2 6.8 12.2 3.1 6.3 12.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.10 001265942.2_29623001_3 - 3.3 6.4 4.9 4.3 6.1 4.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mtc1 PF10310.7 001265942.2_29623001_3 - 4.6 6.0 12.5 6.2 5.5 12.5 1.1 1 0 0 1 1 1 0 Maintenance of telomere capping protein 1 Connexin PF00029.17 001265942.2_29623001_3 - 6.3 6.4 6.0 8.7 5.9 6.0 1.2 1 0 0 1 1 1 0 Connexin U79_P34 PF03064.14 001265942.2_29623001_3 - 7.5 5.7 19.7 11 5.1 19.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pkinase PF00069.23 001265947.1_29623001_2 - 2.1e-56 191.1 0.0 2.6e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001265947.1_29623001_2 - 2.2e-38 131.9 0.0 2.8e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001265947.1_29623001_2 - 1.8e-05 24.1 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.9 001265947.1_29623001_2 - 0.0075 15.2 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.21 001265947.1_29623001_2 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.18 001265947.1_29623001_2 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.20 001265947.1_29623001_2 - 0.15 11.5 0.2 0.28 10.6 0.2 1.3 1 0 0 1 1 1 0 RIO1 family SH3_1 PF00018.26 001265957.1_29629001_1 - 1.3e-24 85.4 1.4 9.4e-12 44.2 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 001265957.1_29629001_1 - 1.3e-22 79.2 1.7 5e-12 45.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.21 001265957.1_29629001_1 - 3.3e-21 75.2 0.5 3.3e-21 75.2 0.5 2.4 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.15 001265957.1_29629001_1 - 7.7e-20 70.2 0.2 8.2e-10 38.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.4 001265957.1_29629001_1 - 0.0049 17.3 0.4 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 Helically-extended SH3 domain SH3_3 PF08239.9 001265957.1_29629001_1 - 0.018 15.2 0.2 0.038 14.1 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain DUF4665 PF15679.3 001265957.1_29629001_1 - 3.1 8.3 8.2 5.2 7.6 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) APS_kinase PF01583.18 001266008.1_29628001_3 - 5.4e-71 237.5 0.0 8.1e-71 236.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.15 001266008.1_29628001_3 - 3.2e-67 226.0 0.0 4.6e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.4 001266008.1_29628001_3 - 4.1e-52 175.9 0.0 6.7e-52 175.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.4 001266008.1_29628001_3 - 4.8e-05 23.4 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001266008.1_29628001_3 - 0.0024 18.2 0.0 0.0068 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.14 001266008.1_29628001_3 - 0.16 11.7 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 zf-H2C2_2 PF13465.4 001266012.1_29629001_2 - 1e-23 82.5 90.3 3.1e-05 24.1 5.9 12.2 13 0 0 13 13 13 8 Zinc-finger double domain BTB PF00651.29 001266012.1_29629001_2 - 7.5e-22 77.5 0.1 1.3e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.24 001266012.1_29629001_2 - 2.3e-15 55.9 84.6 8.5e-05 22.7 2.1 11.5 11 0 0 11 11 11 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001266012.1_29629001_2 - 3.6e-13 49.0 84.0 0.11 13.2 0.8 11.3 11 0 0 11 11 11 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001266012.1_29629001_2 - 1.5e-05 25.0 48.9 0.00073 19.7 0.0 9.2 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001266012.1_29629001_2 - 3.7e-05 23.3 0.7 3.7e-05 23.3 0.7 6.1 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-met PF12874.5 001266012.1_29629001_2 - 0.00015 21.9 0.4 0.00015 21.9 0.4 7.9 7 0 0 7 7 7 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001266012.1_29629001_2 - 0.00019 21.2 55.3 0.29 11.0 1.2 9.5 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001266012.1_29629001_2 - 0.0015 18.6 1.7 0.0015 18.6 1.7 4.9 3 2 2 5 5 5 1 C2H2-type zinc ribbon Mad3_BUB1_II PF08171.9 001266013.2_29626001_2 - 0.2 11.6 0.0 0.32 11.0 0.0 1.2 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Gln-synt_C PF00120.22 001266013.2_29626001_3 - 1.4e-17 63.6 0.0 3.9e-13 49.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.17 001266013.2_29626001_3 - 3.4e-12 45.8 0.0 5.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RRM_1 PF00076.20 001098064.1_06524001_3 - 1.3e-35 120.9 0.4 5.7e-17 61.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001098064.1_06524001_3 - 4.9e-18 64.9 0.7 1.8e-08 34.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif CBFNT PF08143.9 001098064.1_06524001_3 - 1.1e-12 49.0 27.5 1.1e-12 49.0 27.5 2.6 3 0 0 3 3 3 1 CBFNT (NUC161) domain RRM_3 PF08777.9 001098064.1_06524001_3 - 1.3e-05 25.0 0.5 0.05 13.5 0.1 2.5 2 1 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.4 001098064.1_06524001_3 - 0.00023 20.9 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif NID PF07292.11 001098064.1_06524001_3 - 0.0038 17.7 0.6 0.049 14.2 0.0 2.4 2 1 0 2 2 2 1 Nmi/IFP 35 domain (NID) Glyco_transf_6 PF03414.11 132148.1_29524120_2 - 1.2e-100 336.3 1.5 1.6e-100 335.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 TAS2R PF05296.11 001039855.1_32322001_1 - 1.4e-72 244.3 41.8 1.6e-72 244.0 41.8 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) TAS2R PF05296.11 001039866.1_32322001_1 - 5.1e-82 275.3 30.6 5.7e-82 275.1 30.6 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) TAS2R PF05296.11 001039856.1_32322001_1 - 4.6e-72 242.6 29.2 6e-72 242.2 29.2 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) TAS2R PF05296.11 001039873.1_32322001_1 - 9.3e-71 238.3 34.1 1.1e-70 238.0 34.1 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Ion_trans PF00520.29 001246327.1_32329001_1 - 5.2e-219 723.3 86.3 5.5e-81 271.3 12.6 5.1 4 1 0 4 4 4 4 Ion transport protein Na_trans_cytopl PF11933.6 001246327.1_32329001_1 - 8.1e-56 189.1 0.5 1.8e-55 188.0 0.5 1.6 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.11 001246327.1_32329001_1 - 6.4e-22 78.7 0.0 4e-21 76.1 0.0 2.2 2 0 0 2 2 2 1 Sodium ion transport-associated GPHH PF16905.3 001246327.1_32329001_1 - 3.5e-06 26.6 0.0 8.2e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.10 001246327.1_32329001_1 - 0.00015 20.5 79.3 0.00062 18.4 12.1 9.1 6 3 3 9 9 9 6 Polycystin cation channel IQ PF00612.25 001246327.1_32329001_1 - 0.0094 15.5 0.2 0.035 13.7 0.2 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Lustrin_cystein PF14625.4 001246327.1_32329001_1 - 0.093 13.0 0.2 0.35 11.2 0.2 2.0 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain ART PF01129.16 001009134.3_39723001_2 - 8.2e-52 175.6 1.3 1e-51 175.3 1.3 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.12 001009134.3_39723001_2 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme SUI1 PF01253.20 001252632.1_32324001_3 - 5.8e-20 71.5 0.0 2.8e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor SUI1 PUA PF01472.18 001252632.1_32324001_3 - 0.00013 21.7 0.0 0.00073 19.3 0.0 2.1 2 0 0 2 2 2 1 PUA domain SWIB PF02201.16 001252632.1_32324001_3 - 0.0055 16.4 0.4 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain PPTA PF01239.20 001252633.1_32323001_1 - 9.6e-25 85.5 8.1 8.8e-07 28.4 0.0 6.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Amelotin PF15757.3 001319646.1_32322001_1 - 1.1e-64 217.6 22.2 1.4e-64 217.2 22.2 1.1 1 0 0 1 1 1 1 Amelotin SOBP PF15279.4 001104532.1_32326001_1 - 5.2e-88 296.6 38.6 5.2e-88 296.6 38.6 3.8 4 0 0 4 4 4 1 Sine oculis-binding protein zf-FCS PF06467.12 001104532.1_32326001_1 - 0.0067 16.2 18.5 0.017 15.0 1.3 3.5 3 0 0 3 3 3 2 MYM-type Zinc finger with FCS sequence motif Pyr_redox_2 PF07992.12 001256357.1_32323001_1 - 1e-56 192.2 0.1 1.2e-56 192.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.20 001256357.1_32323001_1 - 1.9e-28 98.8 0.0 6.2e-28 97.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.25 001256357.1_32323001_1 - 8.5e-19 67.8 3.4 6.8e-16 58.5 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.4 001256357.1_32323001_1 - 2.7e-16 59.5 0.9 4.8e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.22 001256357.1_32323001_1 - 1.4e-06 27.5 0.2 9.1e-06 24.9 0.1 2.2 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.5 001256357.1_32323001_1 - 2.4e-05 23.8 0.5 4.3e-05 22.9 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.19 001256357.1_32323001_1 - 0.00021 20.5 0.1 0.036 13.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.12 001256357.1_32323001_1 - 0.00024 19.8 0.3 0.0012 17.5 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.4 001256357.1_32323001_1 - 0.00088 19.3 0.3 0.00088 19.3 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.15 001256357.1_32323001_1 - 0.0012 18.0 0.4 0.0063 15.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.20 001256357.1_32323001_1 - 0.0013 17.7 0.8 0.003 16.6 0.3 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.22 001256357.1_32323001_1 - 0.008 15.7 0.1 0.021 14.3 0.1 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.4 001256357.1_32323001_1 - 0.027 14.8 0.2 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.17 001256357.1_32323001_1 - 0.037 13.2 2.9 0.1 11.7 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.10 001256357.1_32323001_1 - 0.17 10.8 0.1 0.27 10.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DNA_methylase PF00145.15 001032969.1_32329001_2 - 2.5e-49 168.3 0.0 1.3e-48 166.0 0.0 2.2 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.6 001032969.1_32329001_2 - 1.9e-46 157.6 1.1 2.8e-46 157.0 0.0 1.9 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.16 001032969.1_32329001_2 - 4.9e-44 148.9 0.9 1.2e-20 73.4 0.2 3.1 3 0 0 3 3 3 2 BAH domain DMAP_binding PF06464.9 001032969.1_32329001_2 - 5.1e-22 78.7 3.5 5.1e-22 78.7 3.5 2.8 2 0 0 2 2 2 1 DMAP1-binding Domain zf-CXXC PF02008.18 001032969.1_32329001_2 - 3.3e-15 55.7 20.8 9.7e-15 54.2 20.8 1.9 1 0 0 1 1 1 1 CXXC zinc finger domain DED PF01335.19 001114360.1_32323001_1 - 4.4e-38 129.3 20.3 1.2e-21 76.6 4.7 2.8 2 0 0 2 2 2 2 Death effector domain Peptidase_C14 PF00656.20 001114360.1_32323001_1 - 4.1e-31 108.7 0.3 7.6e-31 107.8 0.1 1.6 2 0 0 2 2 2 1 Caspase domain adh_short_C2 PF13561.4 001281709.1_32322001_1 - 2.4e-58 197.3 0.0 3.2e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001281709.1_32322001_1 - 1.6e-49 167.9 0.0 1.9e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001281709.1_32322001_1 - 5.1e-09 36.1 0.1 7.4e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001281709.1_32322001_1 - 0.0006 19.2 0.1 0.0012 18.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.8 001281709.1_32322001_1 - 0.006 15.8 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.4 001281709.1_32322001_1 - 0.013 15.3 0.1 0.02 14.7 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding F420_oxidored PF03807.15 001281709.1_32322001_1 - 0.031 14.7 0.1 0.055 13.9 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.16 001281709.1_32322001_1 - 0.12 12.1 0.2 0.19 11.5 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.15 001281709.1_32322001_1 - 0.13 11.2 0.3 0.22 10.4 0.3 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain Ribosomal_S7e PF01251.16 001285477.1_32322001_2 - 1.2e-93 311.9 3.8 1.4e-93 311.7 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e zn-ribbon_14 PF16503.3 001123356.1_32324001_1 - 0.63 9.4 6.1 4.6 6.7 0.6 3.0 3 0 0 3 3 3 0 Zinc-ribbon COesterase PF00135.26 001123356.1_32324001_2 - 1.3e-167 558.7 0.0 1.5e-167 558.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001123356.1_32324001_2 - 2e-10 40.8 1.2 1.1e-09 38.3 1.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001123356.1_32324001_2 - 0.00087 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family IDO PF01231.16 001131057.1_32323001_1 - 2.2e-123 412.1 0.0 2.9e-123 411.7 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.9 001131057.1_32323001_1 - 4.5e-06 25.5 0.1 2.9e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1864) Orn_Arg_deC_N PF02784.14 001291426.2_32325001_1 - 9.1e-62 208.6 0.1 1.2e-61 208.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291426.2_32325001_1 - 1.5e-24 86.0 0.0 2.8e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain IDO PF01231.16 001131058.1_32323001_1 - 2.3e-116 389.0 0.0 4.1e-116 388.2 0.0 1.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.9 001131058.1_32323001_1 - 0.0013 17.4 0.1 0.0089 14.7 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1864) HisK_N PF09385.8 001131058.1_32323001_1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase N terminal DUF2451 PF10474.7 001131058.1_32323001_1 - 0.15 11.7 0.1 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) DUF760 PF05542.9 001131058.1_32323001_1 - 0.46 10.8 1.9 2.5 8.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF760) PIP5K PF01504.16 001136559.1_32325001_1 - 5.3e-92 307.8 0.0 7.1e-92 307.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ald_Xan_dh_C2 PF02738.16 001291666.1_32329001_1 - 6.5e-188 625.5 0.0 8.8e-188 625.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001291666.1_32329001_1 - 5e-45 153.2 0.0 1.1e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001291666.1_32329001_1 - 3e-35 120.8 0.1 7e-35 119.6 0.1 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001291666.1_32329001_1 - 5.6e-30 103.0 0.5 1.4e-29 101.7 0.5 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001291666.1_32329001_1 - 5.4e-29 100.3 0.0 1.6e-28 98.7 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001291666.1_32329001_1 - 6.8e-10 38.6 0.6 6.8e-10 38.6 0.6 2.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain VWA_2 PF13519.4 001136560.1_32323001_1 - 1.1e-24 87.0 0.0 1e-23 83.9 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.26 001136560.1_32323001_1 - 3.5e-07 30.5 0.0 1e-06 29.0 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.18 001136560.1_32323001_1 - 4.9e-07 29.1 10.0 0.00012 21.6 0.4 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif Ssl1 PF04056.12 001136560.1_32323001_1 - 5.2e-07 29.5 0.1 8.5e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like Ald_Xan_dh_C2 PF02738.16 001291667.1_32329001_1 - 3.3e-191 636.3 0.0 4.5e-191 635.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001291667.1_32329001_1 - 1e-44 152.2 0.0 2.6e-44 150.8 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001291667.1_32329001_1 - 1.4e-30 105.7 0.4 3.2e-30 104.6 0.4 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001291667.1_32329001_1 - 5.3e-29 99.9 0.2 1.3e-28 98.6 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001291667.1_32329001_1 - 1e-25 89.7 0.0 4.7e-24 84.4 0.0 2.9 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001291667.1_32329001_1 - 6.5e-10 38.7 1.1 1.4e-09 37.6 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Ald_Xan_dh_C2 PF02738.16 001291668.1_32329001_1 - 2.3e-185 617.0 0.0 3.2e-185 616.6 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001291668.1_32329001_1 - 2.2e-41 141.3 0.0 4.8e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001291668.1_32329001_1 - 7.3e-33 113.1 2.9 1.9e-32 111.8 2.9 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001291668.1_32329001_1 - 7.3e-28 96.2 0.3 1.8e-27 95.0 0.3 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001291668.1_32329001_1 - 9.8e-28 96.2 0.0 3.5e-26 91.2 0.0 3.1 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001291668.1_32329001_1 - 3e-08 33.4 0.1 3e-08 33.4 0.1 3.0 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.15 001291668.1_32329001_1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 DUF218 domain Fer2_3 PF13085.4 001291668.1_32329001_1 - 1.7 8.6 6.6 1.4 8.8 1.2 3.1 2 1 1 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain MHC_I PF00129.16 001291669.1_32323001_1 - 2.4e-52 177.0 1.9 3.2e-52 176.6 1.9 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001291669.1_32323001_1 - 6.8e-17 61.6 0.0 1.4e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_3 PF16497.3 001291669.1_32323001_1 - 2.1e-10 40.3 0.4 2.8e-10 39.9 0.4 1.3 1 0 0 1 1 1 1 MHC-I family domain Ig_3 PF13927.4 001291669.1_32323001_1 - 0.00022 21.7 0.2 0.00046 20.6 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001291669.1_32323001_1 - 0.00028 21.1 0.0 0.00055 20.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001291669.1_32323001_1 - 0.034 14.2 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain 7tm_1 PF00001.19 001145081.1_32323001_1 - 6.7e-38 130.3 10.8 8.9e-38 129.9 10.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.7 001145081.1_32323001_1 - 3.9e-05 22.6 15.1 0.0064 15.3 4.2 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srv PF10323.7 001145081.1_32323001_1 - 0.00013 21.3 9.1 0.00033 20.0 8.0 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.7 001145081.1_32323001_1 - 0.0003 20.1 1.1 0.0003 20.1 1.1 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw Cytochrom_B_N_2 PF13631.4 001145081.1_32323001_1 - 0.001 19.0 0.4 0.0056 16.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB 7TM_GPCR_Srsx PF10320.7 001145081.1_32323001_1 - 0.0052 16.1 8.5 0.46 9.7 3.8 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001145081.1_32323001_1 - 0.061 12.9 9.0 0.88 9.1 9.0 2.1 1 1 0 1 1 1 0 Olfactory receptor DUF898 PF05987.11 001145081.1_32323001_1 - 4.6 6.0 11.2 0.49 9.3 4.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF4190 PF13828.4 001145081.1_32323001_1 - 5 6.8 7.2 0.61 9.8 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DNA_photolyase PF00875.16 001032977.1_32324001_2 - 3.9e-28 98.4 0.0 6.9e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.12 001032977.1_32324001_2 - 0.032 13.6 0.2 0.056 12.8 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase AAA PF00004.27 001293086.1_32323001_2 - 5.4e-43 146.4 0.0 1.2e-42 145.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001293086.1_32323001_2 - 2.2e-07 31.0 0.0 5.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001293086.1_32323001_2 - 2.9e-06 27.2 0.0 1.6e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001293086.1_32323001_2 - 4.2e-06 27.1 0.2 7.6e-05 23.0 0.0 2.7 3 1 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.4 001293086.1_32323001_2 - 2.6e-05 24.4 1.5 0.0054 16.9 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.10 001293086.1_32323001_2 - 9.7e-05 21.6 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.11 001293086.1_32323001_2 - 0.0016 17.4 0.0 0.0032 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.15 001293086.1_32323001_2 - 0.0017 18.0 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.4 001293086.1_32323001_2 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001293086.1_32323001_2 - 0.0025 18.2 0.2 0.02 15.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.9 001293086.1_32323001_2 - 0.0064 16.2 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.19 001293086.1_32323001_2 - 0.0065 15.7 0.1 0.016 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.14 001293086.1_32323001_2 - 0.0073 15.7 0.1 0.14 11.5 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein ATPase PF06745.11 001293086.1_32323001_2 - 0.0084 15.3 0.0 0.024 13.8 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.4 001293086.1_32323001_2 - 0.02 15.0 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001293086.1_32323001_2 - 0.023 14.8 3.4 0.052 13.6 3.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001293086.1_32323001_2 - 0.024 14.2 0.1 0.1 12.2 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001293086.1_32323001_2 - 0.027 14.0 0.0 0.077 12.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain TsaE PF02367.15 001293086.1_32323001_2 - 0.044 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001293086.1_32323001_2 - 0.048 12.6 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.4 001293086.1_32323001_2 - 0.05 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.4 001293086.1_32323001_2 - 0.052 13.0 0.0 0.17 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.11 001293086.1_32323001_2 - 0.053 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.20 001293086.1_32323001_2 - 0.065 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.4 001293086.1_32323001_2 - 0.078 12.6 0.5 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.4 001293086.1_32323001_2 - 0.089 13.1 0.6 0.48 10.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.10 001293086.1_32323001_2 - 0.13 11.5 0.2 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.4 001293086.1_32323001_2 - 0.13 12.5 0.2 0.44 10.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain Laminin_II PF06009.10 001293086.1_32323001_2 - 0.19 11.6 3.4 1.3 9.0 0.9 2.7 3 0 0 3 3 3 0 Laminin Domain II DivIC PF04977.13 001293086.1_32323001_2 - 0.42 10.3 3.4 1 9.0 3.4 1.6 1 0 0 1 1 1 0 Septum formation initiator MscS_porin PF12795.5 001293086.1_32323001_2 - 4.1 6.7 11.6 6.5 6.1 11.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain V-set PF07686.15 001146331.1_32323001_1 - 3.3e-13 49.6 0.1 5.8e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001146331.1_32323001_1 - 7.1e-05 23.2 0.7 0.00015 22.2 0.0 1.9 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.14 001146331.1_32323001_1 - 0.00013 21.8 0.0 0.00037 20.4 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.23 001146331.1_32323001_1 - 0.00018 21.5 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain DUF1049 PF06305.9 001146331.1_32323001_1 - 0.016 14.9 0.8 0.037 13.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Orn_Arg_deC_N PF02784.14 001293687.1_32325001_3 - 9.2e-69 231.5 0.0 1.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001293687.1_32325001_3 - 2.8e-20 72.3 0.0 5.1e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Snf7 PF03357.19 001159423.1_32322001_1 - 6.7e-13 48.5 17.2 1e-12 47.8 17.2 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.12 001159423.1_32322001_1 - 0.026 14.3 10.5 0.071 12.9 10.5 1.7 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.3 001159423.1_32322001_1 - 0.18 11.3 1.5 0.24 10.9 0.4 1.7 1 1 1 2 2 2 0 Dimethlysulfonioproprionate lyase Fes1 PF08609.8 001159423.1_32322001_1 - 8.3 7.2 10.0 7.9 7.3 5.8 2.7 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Globin PF00042.20 001035515.1_32321001_1 - 7.9e-16 58.5 0.0 1.1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Globin Peptidase_C14 PF00656.20 001037970.1_32322001_1 - 4.2e-54 184.0 0.2 4.9e-54 183.8 0.2 1.1 1 0 0 1 1 1 1 Caspase domain Tachystatin_B PF11478.6 001037970.1_32322001_1 - 1.1 9.2 4.8 0.33 10.8 0.7 2.3 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B Peptidase_C14 PF00656.20 001037972.1_32322001_1 - 9e-55 186.2 0.2 1.1e-54 185.8 0.2 1.1 1 0 0 1 1 1 1 Caspase domain COesterase PF00135.26 001171573.1_32325001_1 - 3.7e-199 662.8 0.0 4.5e-199 662.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001171573.1_32325001_1 - 5.1e-07 29.6 0.1 3.2e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.26 001171572.1_32326001_1 - 1.4e-191 637.8 0.0 1.7e-191 637.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001171572.1_32326001_1 - 6.1e-07 29.4 0.3 4.5e-06 26.5 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sarcoglycan_2 PF05510.11 001171572.1_32326001_1 - 0.036 12.7 0.0 0.081 11.6 0.0 1.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon MHC_I PF00129.16 001171834.1_32323001_3 - 3.8e-49 166.5 0.0 5.5e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001171834.1_32323001_3 - 2.5e-15 56.6 0.0 6.3e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001171834.1_32323001_3 - 0.00087 19.7 0.1 0.0049 17.3 0.0 2.3 1 1 1 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.4 001171834.1_32323001_3 - 0.0011 19.1 0.0 0.0069 16.6 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain PepSY_TM PF03929.14 001171834.1_32323001_3 - 0.11 11.8 0.2 0.39 9.9 0.1 1.4 1 1 0 1 1 1 0 PepSY-associated TM region PdxJ PF03740.11 001171834.1_32323001_3 - 0.14 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ MHC_I PF00129.16 001171836.1_32323001_1 - 8.8e-67 224.0 1.1 1.2e-66 223.6 1.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001171836.1_32323001_1 - 1.2e-18 67.2 0.1 3.9e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001171836.1_32323001_1 - 0.0001 22.7 0.0 0.00026 21.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001171836.1_32323001_1 - 0.00013 21.8 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 001171836.1_32323001_1 - 0.00019 21.5 0.0 0.00036 20.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001171836.1_32323001_1 - 0.0017 18.4 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain MHC_I_3 PF16497.3 001171836.1_32323001_1 - 0.0027 17.1 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 MHC-I family domain I-set PF07679.14 001171836.1_32323001_1 - 0.0084 16.0 0.1 0.053 13.5 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain MHC_I PF00129.16 001171835.1_32324001_3 - 1.7e-57 193.8 1.9 2.7e-57 193.1 1.9 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001171835.1_32324001_3 - 5.1e-15 55.6 0.1 1.6e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001171835.1_32324001_3 - 4e-09 36.1 3.1 7.2e-09 35.3 3.1 1.4 1 0 0 1 1 1 1 MHC_I C-terminus MHC_I_3 PF16497.3 001171835.1_32324001_3 - 3.4e-06 26.6 0.0 5.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 MHC-I family domain Ig_3 PF13927.4 001171835.1_32324001_3 - 0.00023 21.6 0.1 0.018 15.5 0.0 2.7 1 1 1 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.4 001171835.1_32324001_3 - 0.00033 20.8 0.0 0.048 13.9 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain EphA2_TM PF14575.4 001171835.1_32324001_3 - 0.049 14.3 0.0 0.36 11.5 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ig PF00047.23 001171835.1_32324001_3 - 0.052 13.6 0.1 0.28 11.2 0.0 2.1 2 1 0 2 2 2 0 Immunoglobulin domain COesterase PF00135.26 001171833.1_32326001_1 - 2.9e-195 649.9 0.0 3.4e-195 649.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001171833.1_32326001_1 - 1.8e-05 24.5 0.2 0.00011 22.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lamp PF01299.15 001171833.1_32326001_1 - 2.6 7.4 3.9 21 4.4 2.1 2.1 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) MHC_I PF00129.16 001171837.1_32323001_1 - 4.6e-63 211.9 0.9 7.2e-63 211.2 0.9 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001171837.1_32323001_1 - 6.7e-15 55.2 0.0 1.7e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001171837.1_32323001_1 - 1.4e-09 37.6 0.2 3.3e-09 36.4 0.2 1.7 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001171837.1_32323001_1 - 0.0029 18.1 0.2 0.02 15.4 0.0 2.5 2 1 1 3 3 3 1 Immunoglobulin domain SIT PF15330.4 001171837.1_32323001_1 - 0.0072 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT ig PF00047.23 001171837.1_32323001_1 - 0.013 15.5 0.1 0.32 11.0 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain C2-set_2 PF08205.10 001171837.1_32323001_1 - 0.013 15.4 0.1 0.034 14.1 0.1 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain PepSY_TM PF03929.14 001171837.1_32323001_1 - 0.12 11.6 1.5 0.18 11.1 1.5 1.7 1 1 0 1 1 1 0 PepSY-associated TM region stn_TNFRSF12A PF12191.6 001171837.1_32323001_1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MHC_I_2 PF14586.4 001171837.1_32323001_1 - 0.16 11.7 0.2 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 RRM_1 PF00076.20 001172361.1_32326001_1 - 9.9e-07 28.4 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.5 001172361.1_32326001_1 - 0.032 14.6 49.8 0.068 13.6 49.8 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MOZ_SAS PF01853.16 001172362.1_32324001_1 - 3.9e-86 287.1 1.4 6.1e-86 286.5 1.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-C2HC PF01530.16 001172362.1_32324001_1 - 6.6e-14 51.7 5.9 6.6e-14 51.7 5.9 1.9 2 0 0 2 2 2 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.5 001172362.1_32324001_1 - 0.029 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met PF12874.5 001172362.1_32324001_1 - 0.083 13.2 0.5 0.23 11.8 0.5 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ABC_membrane PF00664.21 001190792.1_32328001_1 - 7.4e-167 553.7 29.6 1e-89 300.7 12.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001190792.1_32328001_1 - 1.1e-74 249.3 0.7 3e-37 128.1 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.17 001190792.1_32328001_1 - 1.5e-16 60.3 6.0 5.1e-07 29.2 0.0 3.9 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.4 001190792.1_32328001_1 - 4.2e-10 40.1 1.8 0.00079 19.7 0.2 2.9 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.7 001190792.1_32328001_1 - 7.4e-10 38.1 0.3 0.00028 19.7 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.4 001190792.1_32328001_1 - 8.6e-09 35.6 1.4 0.0025 18.0 0.2 3.3 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.14 001190792.1_32328001_1 - 2.1e-07 30.8 0.1 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 G-alpha PF00503.18 001190792.1_32328001_1 - 7.8e-07 28.4 0.1 0.013 14.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.10 001190792.1_32328001_1 - 1.1e-06 27.9 0.6 0.0066 15.6 0.0 3.3 4 0 0 4 4 3 2 Zeta toxin AAA PF00004.27 001190792.1_32328001_1 - 2.8e-06 27.7 5.0 0.02 15.2 0.2 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.4 001190792.1_32328001_1 - 3.8e-06 26.4 1.3 0.049 13.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.12 001190792.1_32328001_1 - 1.1e-05 25.3 1.2 0.31 10.9 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Rad17 PF03215.13 001190792.1_32328001_1 - 1.5e-05 24.0 0.0 0.02 13.7 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_15 PF13175.4 001190792.1_32328001_1 - 2e-05 24.3 0.1 0.22 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.4 001190792.1_32328001_1 - 0.00014 21.5 1.5 0.46 10.0 0.3 3.1 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.4 001190792.1_32328001_1 - 0.00021 21.4 4.5 0.47 10.6 0.4 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.4 001190792.1_32328001_1 - 0.00094 18.9 0.2 7.6 6.1 0.0 4.1 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.18 001190792.1_32328001_1 - 0.00095 19.0 0.3 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase Mg_chelatase PF01078.19 001190792.1_32328001_1 - 0.00098 18.4 0.0 0.34 10.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PRK PF00485.16 001190792.1_32328001_1 - 0.0011 18.7 0.0 0.99 9.0 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.11 001190792.1_32328001_1 - 0.0012 17.9 0.1 0.48 9.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.20 001190792.1_32328001_1 - 0.0018 18.5 0.0 3.4 8.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.15 001190792.1_32328001_1 - 0.0039 16.8 0.5 25 4.4 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF87 PF01935.15 001190792.1_32328001_1 - 0.004 17.1 4.3 1.7 8.5 0.1 3.5 4 0 0 4 4 4 2 Domain of unknown function DUF87 tRNA_lig_kinase PF08303.9 001190792.1_32328001_1 - 0.0054 16.7 0.0 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_18 PF13238.4 001190792.1_32328001_1 - 0.0074 16.7 0.0 6.5 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.10 001190792.1_32328001_1 - 0.0074 16.1 0.0 3.3 7.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain DUF2207 PF09972.7 001190792.1_32328001_1 - 0.0083 14.8 0.0 0.0083 14.8 0.0 3.3 3 1 0 4 4 4 1 Predicted membrane protein (DUF2207) ATP-synt_ab PF00006.23 001190792.1_32328001_1 - 0.011 15.3 0.0 3.9 6.9 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.4 001190792.1_32328001_1 - 0.012 15.8 0.0 7 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.4 001190792.1_32328001_1 - 0.015 15.4 0.0 5 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.4 001190792.1_32328001_1 - 0.023 14.1 1.5 4 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.4 001190792.1_32328001_1 - 0.029 13.9 0.1 5.5 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.4 001190792.1_32328001_1 - 0.036 14.5 0.0 9.7 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.20 001190792.1_32328001_1 - 0.041 12.8 0.7 6.1 5.6 0.1 2.7 2 0 0 2 2 2 0 NB-ARC domain RepB-RCR_reg PF10723.7 001190792.1_32328001_1 - 0.072 12.9 0.1 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Replication regulatory protein RepB MMR_HSR1 PF01926.21 001190792.1_32328001_1 - 0.1 12.6 0.0 16 5.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase MHC_I PF00129.16 001193323.1_32323001_3 - 3.2e-37 127.7 0.5 4.8e-37 127.1 0.5 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I_3 PF16497.3 001193323.1_32323001_3 - 5.8e-06 25.8 0.3 1.1e-05 24.9 0.3 1.4 1 0 0 1 1 1 1 MHC-I family domain MHC_I_2 PF14586.4 001193323.1_32323001_3 - 1.2e-05 25.1 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 MHC_I PF00129.16 001193324.1_32324001_2 - 9.6e-29 100.1 0.1 1.3e-28 99.6 0.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001193324.1_32324001_2 - 1e-12 48.2 0.9 2.3e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin C1-set domain MHC_I_3 PF16497.3 001193324.1_32324001_2 - 2.2e-05 23.9 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 MHC-I family domain Peptidase_C14 PF00656.20 001040148.1_32323001_1 - 1e-31 110.7 0.1 1.2e-31 110.4 0.1 1.1 1 0 0 1 1 1 1 Caspase domain PYRIN PF02758.14 001040148.1_32323001_1 - 3.9e-10 39.7 0.1 1.1e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 PAAD/DAPIN/Pyrin domain DUF1256 PF06866.9 001040148.1_32323001_1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1256) RCC_reductase PF06405.9 001040148.1_32323001_1 - 0.11 11.5 0.2 0.33 10.0 0.1 1.8 2 0 0 2 2 2 0 Red chlorophyll catabolite reductase (RCC reductase) Prion PF00377.16 001040028.2_32322001_1 - 2.9e-32 110.8 2.6 3.8e-32 110.5 2.6 1.1 1 0 0 1 1 1 1 Prion/Doppel alpha-helical domain Prion_bPrPp PF11587.6 001040028.2_32322001_1 - 1.3e-14 53.6 2.2 2.4e-14 52.7 2.2 1.5 1 0 0 1 1 1 1 Major prion protein bPrPp - N terminal Gly-zipper_Omp PF13488.4 001040028.2_32322001_1 - 0.00067 19.5 1.7 0.0015 18.3 1.7 1.5 1 0 0 1 1 1 1 Glycine zipper SARAF PF06682.10 001040028.2_32322001_1 - 0.3 10.6 9.7 0.48 9.9 9.7 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Lem_TRP PF08262.9 001040028.2_32322001_3 - 0.49 10.4 2.1 78 3.5 0.1 3.7 4 0 0 4 4 4 0 Leucophaea maderae tachykinin-related peptide MHC_I PF00129.16 001079813.1_32322001_1 - 6.1e-35 120.3 0.0 8.4e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001079813.1_32322001_1 - 2e-14 53.7 0.0 3.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_2 PF13895.4 001079813.1_32322001_1 - 0.027 14.7 0.0 0.13 12.5 0.0 2.1 2 1 0 2 2 2 0 Immunoglobulin domain C2-set_2 PF08205.10 001079813.1_32322001_1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain MHC_I PF00129.16 001079820.1_32323001_1 - 3.1e-74 248.3 5.5 4.1e-74 247.9 5.5 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001079820.1_32323001_1 - 5.7e-15 55.4 0.0 2e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001079820.1_32323001_1 - 9.1e-10 38.2 5.3 1.7e-09 37.3 5.3 1.5 1 0 0 1 1 1 1 MHC_I C-terminus MHC_I_3 PF16497.3 001079820.1_32323001_1 - 3.8e-07 29.7 0.1 6.1e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 MHC-I family domain C2-set_2 PF08205.10 001079820.1_32323001_1 - 0.0018 18.2 0.0 0.0058 16.5 0.0 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 001079820.1_32323001_1 - 0.0095 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001079820.1_32323001_1 - 0.0099 16.3 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.4 001079820.1_32323001_1 - 0.16 12.7 0.2 0.45 11.2 0.0 1.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_C14 PF00656.20 001093773.1_32322001_1 - 9e-35 120.7 0.0 1.1e-34 120.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CRM1_C PF08767.9 001093773.1_32322001_1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal CD4-extracel PF09191.8 001099290.1_32325001_2 - 8.3e-31 106.5 1.3 2e-30 105.2 0.0 2.3 3 0 0 3 3 3 1 CD4, extracellular ig PF00047.23 001099290.1_32325001_2 - 5.6e-20 71.2 2.9 7.8e-13 48.3 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.4 001099290.1_32325001_2 - 3.4e-15 56.3 0.8 2.1e-05 24.9 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Tcell_CD4_C PF12104.6 001099290.1_32325001_2 - 3.9e-15 55.3 5.5 1.3e-14 53.7 5.5 1.9 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region V-set PF07686.15 001099290.1_32325001_2 - 8.6e-12 45.1 3.1 1.4e-10 41.2 0.2 3.2 2 1 1 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.14 001099290.1_32325001_2 - 1.3e-10 41.1 0.2 3.8e-06 26.8 0.1 3.0 1 1 1 2 2 2 2 Immunoglobulin I-set domain C2-set PF05790.13 001099290.1_32325001_2 - 9.5e-10 38.4 8.0 8.3e-06 25.8 0.4 3.5 3 0 0 3 3 3 2 Immunoglobulin C2-set domain Ig_2 PF13895.4 001099290.1_32325001_2 - 2.5e-09 37.2 0.3 0.00086 19.5 0.0 3.6 2 1 1 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.3 001099290.1_32325001_2 - 0.0008 19.3 0.1 0.74 9.8 0.0 3.6 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.6 001099290.1_32325001_2 - 0.0048 17.0 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 7tm_3 PF00003.20 001099533.1_32325001_1 - 1.9e-62 211.0 23.6 3e-62 210.3 23.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099533.1_32325001_1 - 8.8e-53 179.5 0.0 1.2e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099533.1_32325001_1 - 5.3e-18 64.6 11.9 1e-17 63.7 11.9 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099533.1_32325001_1 - 0.0001 22.0 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein TNFR_c6 PF00020.16 001099533.1_32325001_1 - 2.7 8.4 8.7 4.2 7.7 2.9 2.8 1 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region Neur_chan_LBD PF02931.21 001168261.1_32324001_1 - 3.2e-50 170.4 0.2 6.3e-50 169.5 0.0 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001168261.1_32324001_1 - 1.9e-48 165.5 0.0 2.5e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.7 001168261.1_32324001_1 - 1.5 6.9 4.9 2.1 6.4 4.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 7tm_3 PF00003.20 001099536.1_32325001_1 - 6.4e-67 225.6 19.9 9.7e-67 225.0 19.9 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099536.1_32325001_1 - 1.2e-52 179.1 0.2 1.6e-52 178.6 0.2 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099536.1_32325001_1 - 6.5e-16 57.9 14.7 6.5e-16 57.9 14.7 1.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Flu_NS1 PF00600.17 001099536.1_32325001_1 - 0.027 13.9 0.2 0.049 13.1 0.2 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) PMM PF03332.11 001099536.1_32325001_1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase TNFR_c6 PF00020.16 001099536.1_32325001_1 - 0.14 12.5 11.8 0.31 11.4 7.2 2.7 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.11 001099536.1_32325001_1 - 7.6 6.2 15.6 0.71 9.6 6.9 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like EcsB PF05975.10 001099536.1_32325001_1 - 8 5.1 11.0 0.37 9.5 2.3 2.2 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB 7tm_3 PF00003.20 001099538.1_32325001_1 - 8.6e-67 225.2 19.4 1.4e-66 224.6 19.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099538.1_32325001_1 - 2.7e-51 174.6 0.1 3.8e-51 174.1 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099538.1_32325001_1 - 4e-17 61.8 13.6 1.2e-16 60.3 13.6 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Flu_NS1 PF00600.17 001099538.1_32325001_1 - 0.029 13.8 0.2 0.054 12.9 0.2 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) Ephrin_rec_like PF07699.11 001099538.1_32325001_1 - 0.95 9.1 10.9 0.47 10.1 7.6 2.1 1 1 1 2 2 2 0 Putative ephrin-receptor like 7tm_3 PF00003.20 001099540.1_32325001_1 - 1e-66 225.0 18.6 1.6e-66 224.3 18.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099540.1_32325001_1 - 1.5e-52 178.7 0.5 2.2e-52 178.2 0.5 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099540.1_32325001_1 - 1.2e-16 60.3 12.9 3.2e-16 58.9 12.9 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099540.1_32325001_1 - 0.13 11.9 5.0 0.38 10.4 5.0 1.8 1 0 0 1 1 1 0 Putative ephrin-receptor like 7tm_3 PF00003.20 001099541.1_32325001_1 - 2.7e-65 220.3 18.9 4.3e-65 219.7 18.9 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099541.1_32325001_1 - 2.1e-52 178.3 0.2 3.3e-52 177.6 0.2 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099541.1_32325001_1 - 1.7e-16 59.7 13.1 3.6e-16 58.7 13.1 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.16 001099541.1_32325001_1 - 0.36 11.1 9.3 0.84 10.0 5.7 2.7 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region DUF2157 PF09925.7 001099541.1_32325001_1 - 0.59 9.8 4.5 7.4 6.2 0.6 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Ephrin_rec_like PF07699.11 001099541.1_32325001_1 - 2.2 8.0 12.4 0.22 11.2 4.9 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like V-set PF07686.15 001195408.1_32323001_1 - 1.4e-08 34.7 0.7 5.1e-08 32.9 0.7 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.14 001195408.1_32323001_1 - 2.3e-07 30.6 0.2 5e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 001195408.1_32323001_1 - 4e-07 30.4 0.2 8e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001195408.1_32323001_1 - 3.2e-05 23.9 0.2 6.4e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ITAM PF02189.13 001195408.1_32323001_1 - 0.0016 18.6 0.1 0.0031 17.8 0.1 1.5 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif Ig_2 PF13895.4 001195408.1_32323001_1 - 0.043 14.0 0.2 0.089 13.0 0.2 1.4 1 0 0 1 1 1 0 Immunoglobulin domain HH_signal PF01085.16 001198553.1_32323001_1 - 5e-89 295.9 0.0 6.7e-89 295.5 0.0 1.2 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Hint PF01079.18 001198553.1_32323001_1 - 4.7e-75 251.6 0.0 6.1e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 Hint module Peptidase_M15_3 PF08291.9 001198553.1_32323001_1 - 0.00044 20.2 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M15 Ribosomal_S6e PF01092.17 001198553.1_32323001_1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6e GLTP PF08718.9 001199078.1_32324001_1 - 1.3e-42 145.4 0.0 3e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH PF00169.27 001199078.1_32324001_1 - 4.7e-12 46.2 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.4 001199078.1_32324001_1 - 1.4e-05 25.2 0.1 4.2e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.4 001199078.1_32324001_1 - 7.5e-05 23.0 0.2 0.00047 20.4 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain 7tm_3 PF00003.20 001099545.1_32326001_1 - 5.4e-63 212.8 23.7 8.1e-63 212.2 23.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099545.1_32326001_1 - 4.2e-48 164.1 0.0 6.1e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099545.1_32326001_1 - 1.2e-19 69.9 15.5 3.1e-19 68.6 15.5 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099545.1_32326001_1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein DUF4870 PF09685.8 001099545.1_32326001_1 - 3 7.8 10.3 0.12 12.4 3.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) AKAP2_C PF15304.4 001204135.1_32325001_1 - 2.8e-10 39.9 13.5 2.8e-10 39.9 13.5 4.4 3 2 1 4 4 4 1 A-kinase anchor protein 2 C-terminus Ank_2 PF12796.5 001204074.1_32329001_1 - 2.7e-150 489.2 38.1 1.7e-19 70.1 1.1 12.3 3 3 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001204074.1_32329001_1 - 9.2e-120 389.5 17.2 4.4e-10 39.7 0.0 16.2 8 3 7 17 17 17 16 Ankyrin repeats (many copies) Ank PF00023.28 001204074.1_32329001_1 - 3.7e-112 362.2 50.9 4.9e-08 32.9 0.0 24.8 24 0 0 24 24 24 22 Ankyrin repeat Ank_3 PF13606.4 001204074.1_32329001_1 - 1.1e-104 329.4 30.7 6.2e-05 23.0 0.0 25.6 25 0 0 25 25 25 21 Ankyrin repeat Ank_5 PF13857.4 001204074.1_32329001_1 - 8.3e-99 321.8 50.6 5.3e-08 32.9 0.0 21.0 6 4 14 21 21 21 20 Ankyrin repeats (many copies) KH_1 PF00013.27 001204074.1_32329001_1 - 1.1e-14 53.9 0.6 2.9e-14 52.5 0.6 1.8 1 0 0 1 1 1 1 KH domain SURF6 PF04935.10 001204074.1_32329001_1 - 0.076 12.6 31.9 0.038 13.6 18.8 2.4 2 0 0 2 2 2 0 Surfeit locus protein 6 BUD22 PF09073.8 001204074.1_32329001_1 - 3.3 6.8 33.8 1.1 8.4 22.2 2.3 2 0 0 2 2 2 0 BUD22 Nop25 PF09805.7 001204074.1_32329001_1 - 8.4 6.7 27.6 7.1 7.0 15.4 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) EMP24_GP25L PF01105.22 001204348.1_32322001_1 - 1e-48 165.6 0.3 1.1e-48 165.4 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 7tm_3 PF00003.20 001099546.1_32325001_1 - 2.5e-66 223.7 19.7 4.5e-66 222.9 19.7 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099546.1_32325001_1 - 6.9e-51 173.3 0.1 1e-50 172.7 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099546.1_32325001_1 - 5.4e-16 58.2 10.7 1.1e-15 57.2 10.7 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099546.1_32325001_1 - 0.021 14.5 6.7 0.057 13.1 6.7 1.7 1 0 0 1 1 1 0 Putative ephrin-receptor like HbrB PF08539.9 001204412.1_32323001_1 - 1.9e-15 57.1 0.5 7.3e-14 52.0 0.0 2.3 1 1 1 2 2 2 2 HbrB-like RhoGAP PF00620.25 001204413.1_32323001_1 - 8.7e-43 145.6 0.0 1.6e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.4 001204413.1_32323001_1 - 1e-38 132.4 1.5 2.3e-38 131.3 1.5 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.18 001204413.1_32323001_1 - 6.8e-12 45.2 0.1 1.5e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Acetyltransf_11 PF13720.4 001204413.1_32323001_1 - 0.025 14.9 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Brix PF04427.16 001204452.1_32323001_1 - 4.3e-43 147.5 0.0 5.9e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain NDK PF00334.17 001204523.1_32321001_1 - 1.8e-54 183.2 0.0 2.1e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.17 001204525.1_32321001_1 - 9.9e-53 177.6 0.0 1.1e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Fucokinase PF07959.10 001204804.1_32324001_1 - 2.7e-141 471.1 0.0 3.2e-141 470.9 0.0 1.0 1 0 0 1 1 1 1 L-fucokinase LEAP-2 PF07359.9 001204804.1_32324001_1 - 0.11 12.2 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Pkinase_Tyr PF07714.15 001204805.1_32326001_1 - 3.3e-58 196.9 0.0 4.6e-57 193.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.5 001204805.1_32326001_1 - 4e-54 181.0 6.4 1.5e-16 60.6 0.1 6.3 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Pkinase PF00069.23 001204805.1_32326001_1 - 1.9e-46 158.4 0.0 4.9e-46 157.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ank_4 PF13637.4 001204805.1_32326001_1 - 2.2e-46 155.5 22.7 4.3e-10 39.8 0.0 8.3 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.28 001204805.1_32326001_1 - 2.3e-43 144.7 23.4 9e-07 28.9 0.0 11.3 12 0 0 12 12 12 8 Ankyrin repeat Ank_3 PF13606.4 001204805.1_32326001_1 - 1.4e-37 123.3 15.9 0.0003 20.9 0.0 11.6 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.4 001204805.1_32326001_1 - 1e-33 114.7 11.8 3.4e-06 27.1 0.0 9.5 3 2 7 10 10 10 8 Ankyrin repeats (many copies) RIO1 PF01163.20 001204805.1_32326001_1 - 0.042 13.3 1.2 0.14 11.6 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.12 001204805.1_32326001_1 - 0.056 12.7 0.1 0.097 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001204805.1_32326001_1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family 7tm_3 PF00003.20 001099552.1_32325001_1 - 5.7e-67 225.8 20.3 9.1e-67 225.1 20.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099552.1_32325001_1 - 1.9e-49 168.5 0.0 2.8e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099552.1_32325001_1 - 7.5e-18 64.1 12.8 1.4e-17 63.2 12.8 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099552.1_32325001_1 - 0.012 15.3 7.8 0.03 13.9 7.8 1.7 1 0 0 1 1 1 0 Putative ephrin-receptor like Adap_comp_sub PF00928.19 001204849.1_32325001_1 - 1.8e-54 184.8 0.3 2.8e-54 184.1 0.3 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ank_2 PF12796.5 001205050.1_32324001_1 - 7.4e-60 199.4 2.5 8.9e-19 67.7 0.1 5.6 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001205050.1_32324001_1 - 1.2e-45 153.2 5.0 2e-10 40.8 0.2 7.4 5 1 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.4 001205050.1_32324001_1 - 2e-38 125.8 3.6 8.8e-05 22.5 0.0 11.2 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.28 001205050.1_32324001_1 - 1.9e-32 110.2 3.6 7e-05 23.0 0.1 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.4 001205050.1_32324001_1 - 2e-27 94.7 2.2 6e-05 23.2 0.0 8.7 3 1 7 10 10 10 7 Ankyrin repeats (many copies) SOCS_box PF07525.14 001205050.1_32324001_1 - 2.4e-11 43.6 4.9 5.5e-11 42.5 4.9 1.7 1 0 0 1 1 1 1 SOCS box TMEM189_B_dmain PF10520.7 001205090.1_32322001_1 - 6.2e-77 257.6 1.7 8.6e-77 257.1 1.7 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain UQ_con PF00179.24 001205091.1_32322001_3 - 1.4e-17 63.5 0.0 2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001205091.1_32322001_3 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain 7tm_3 PF00003.20 001099556.1_32326001_1 - 1.5e-61 208.0 26.0 2.4e-61 207.4 26.0 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099556.1_32326001_1 - 9.1e-52 176.2 0.0 1.2e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099556.1_32326001_1 - 7.6e-16 57.7 14.3 1.8e-15 56.5 14.3 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR 7tm_3 PF00003.20 001099557.1_32325001_1 - 2.6e-63 213.8 25.5 2.6e-63 213.8 25.5 1.6 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099557.1_32325001_1 - 1.8e-55 188.4 0.4 2.4e-55 187.9 0.4 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099557.1_32325001_1 - 2.9e-18 65.4 12.1 6.5e-18 64.3 12.1 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099557.1_32325001_1 - 0.052 13.2 4.4 0.14 11.8 4.4 1.7 1 0 0 1 1 1 0 Putative ephrin-receptor like Peripla_BP_6 PF13458.4 001099557.1_32325001_1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DNA_pol_B PF00136.19 001099557.1_32325001_1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family B DUF4870 PF09685.8 001099557.1_32325001_1 - 6.3 6.8 11.6 0.51 10.3 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) TNF PF00229.16 001205142.1_32322001_2 - 4.4e-09 36.2 0.0 6.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family RCC1 PF00415.16 001205209.1_32323001_1 - 3.7e-79 261.0 17.4 1.2e-14 54.5 0.1 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 001205209.1_32323001_1 - 1.5e-28 97.8 34.2 5.8e-09 35.4 0.3 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.12 001205209.1_32323001_1 - 0.00036 20.2 0.0 0.73 9.6 0.0 3.1 3 0 0 3 3 3 2 Peptidase family C25, C terminal ig-like domain SUKH-3 PF14433.4 001205209.1_32323001_1 - 0.0074 16.6 1.1 11 6.3 0.1 4.2 4 0 0 4 4 4 1 SUKH-3 immunity protein PapC_C PF13953.4 001205209.1_32323001_1 - 1.3 8.8 4.1 52 3.7 0.0 3.9 5 0 0 5 5 5 0 PapC C-terminal domain 7tm_3 PF00003.20 001099559.1_32326001_1 - 8.7e-61 205.6 26.2 2.2e-60 204.2 25.8 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099559.1_32326001_1 - 4.9e-52 177.0 0.1 6.6e-52 176.6 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099559.1_32326001_1 - 4.3e-17 61.7 15.5 1e-16 60.5 15.5 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR RRM_1 PF00076.20 001205264.1_32327001_2 - 2.1e-08 33.8 0.0 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.6 001205264.1_32327001_2 - 0.014 15.6 8.3 1 9.6 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CTU2 PF10288.7 001205264.1_32327001_2 - 0.89 9.7 0.0 0.89 9.7 0.0 3.1 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-met PF12874.5 001205264.1_32327001_2 - 1.7 9.0 9.7 2 8.8 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Sirohm_synth_C PF14823.4 001246223.1_32322001_1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal V-set PF07686.15 001246223.1_32322001_3 - 3.2e-11 43.2 0.0 5.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001246223.1_32322001_3 - 0.00029 21.2 0.1 0.00095 19.6 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001246223.1_32322001_3 - 0.00052 19.9 0.0 0.0021 17.9 0.0 2.0 1 1 1 2 2 2 1 Immunoglobulin I-set domain TMEM154 PF15102.4 001246223.1_32322001_3 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family Guanylate_kin PF00625.19 001246224.1_32323001_1 - 1.2e-47 161.8 0.2 2.2e-47 160.9 0.2 1.5 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.6 001246224.1_32323001_1 - 3.1e-22 78.3 6.1 9.1e-22 76.8 6.1 1.9 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.26 001246224.1_32323001_1 - 0.0012 18.2 0.0 0.0047 16.4 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.4 001246224.1_32323001_1 - 0.01 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.15 001246224.1_32323001_1 - 0.025 14.2 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain MHC_I_C PF06623.9 001246247.1_32324001_1 - 1.3e-05 24.8 1.2 2.9e-05 23.8 1.2 1.5 1 0 0 1 1 1 1 MHC_I C-terminus MHC_I PF00129.16 001246247.1_32324001_2 - 4.5e-64 215.2 1.7 6.2e-64 214.7 1.7 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001246247.1_32324001_2 - 1.5e-15 57.3 0.0 3.7e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.10 001246247.1_32324001_2 - 0.026 14.5 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain ig PF00047.23 001246247.1_32324001_2 - 0.1 12.6 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain 7tm_3 PF00003.20 001099561.1_32326001_1 - 2.3e-60 204.2 26.6 2.3e-60 204.2 26.6 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099561.1_32326001_1 - 5.2e-55 186.8 0.0 7e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099561.1_32326001_1 - 7.8e-16 57.7 16.1 1.8e-15 56.5 16.1 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR GTP_EFTU PF00009.25 001252603.1_32327001_1 - 6.9e-65 218.1 0.0 9.3e-65 217.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.16 001252603.1_32327001_1 - 2.9e-33 114.1 0.1 9.2e-33 112.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.22 001252603.1_32327001_1 - 5.2e-22 77.5 0.0 1.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.4 001252603.1_32327001_1 - 2.4e-13 49.8 0.0 5.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.23 001252603.1_32327001_1 - 3.6e-13 49.6 0.2 1.6e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001252603.1_32327001_1 - 1.5e-05 24.9 0.1 3.3e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Oxysterol_BP PF01237.16 001252631.1_32325001_1 - 7.8e-146 485.5 0.4 7.8e-146 485.5 0.4 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH PF00169.27 001252631.1_32325001_1 - 5.2e-16 58.9 0.1 1.6e-15 57.4 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.4 001252631.1_32325001_1 - 7.9e-12 45.2 0.3 1.8e-11 44.1 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.4 001252631.1_32325001_1 - 1.1e-05 25.5 0.0 5.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.4 001252631.1_32325001_1 - 1.6e-05 25.1 4.1 0.0026 18.0 4.1 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain HlyD_D23 PF16576.3 001252631.1_32325001_1 - 0.069 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Syntaxin-6_N PF09177.9 001252631.1_32325001_1 - 0.071 13.5 5.2 0.34 11.4 2.7 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal 7tm_3 PF00003.20 001099565.1_32326001_1 - 1.1e-60 205.3 26.8 2.1e-60 204.3 26.8 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099565.1_32326001_1 - 2.1e-56 191.4 0.0 2.7e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099565.1_32326001_1 - 2.9e-20 71.8 11.8 7.2e-20 70.6 11.8 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF2157 PF09925.7 001099565.1_32326001_1 - 5.3 6.7 7.3 18 5.0 1.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) 7tm_3 PF00003.20 001099570.1_32325001_1 - 3.4e-59 200.4 27.8 5.1e-59 199.8 27.8 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099570.1_32325001_1 - 1.6e-54 185.2 0.0 2.2e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099570.1_32325001_1 - 2.1e-16 59.5 13.0 4.9e-16 58.3 13.0 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099570.1_32325001_1 - 0.00049 19.8 0.0 0.0011 18.7 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein Ephrin_rec_like PF07699.11 001099570.1_32325001_1 - 0.99 9.1 10.9 2.7 7.7 8.7 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like 7tm_3 PF00003.20 001099574.1_32325001_1 - 1.8e-64 217.6 28.6 4e-64 216.5 28.3 1.7 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099574.1_32325001_1 - 1.2e-44 152.7 0.0 1.7e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099574.1_32325001_1 - 3e-18 65.4 12.4 5.1e-18 64.7 11.8 1.8 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR SP2 PF03014.12 001099574.1_32325001_1 - 0.12 10.2 0.1 0.18 9.7 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 Ephrin_rec_like PF07699.11 001099574.1_32325001_1 - 0.24 11.1 4.7 0.54 9.9 4.7 1.6 1 0 0 1 1 1 0 Putative ephrin-receptor like GtrA PF04138.12 001099574.1_32325001_1 - 2.9 8.0 13.1 18 5.5 4.6 3.2 1 1 2 3 3 3 0 GtrA-like protein DUF2873 PF11395.6 001099574.1_32325001_1 - 6.5 6.6 9.2 9.8 6.0 1.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) TNFR_c6 PF00020.16 001099574.1_32325001_1 - 8.7 6.7 9.7 35 4.8 4.3 2.8 1 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region 7tm_3 PF00003.20 001099575.1_32326001_1 - 3.2e-64 216.8 29.6 8.3e-64 215.4 29.6 1.7 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099575.1_32326001_1 - 1.6e-43 149.1 0.0 2.2e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099575.1_32326001_1 - 3.2e-18 65.3 11.9 8.2e-18 64.0 11.9 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099575.1_32326001_1 - 0.00031 20.4 0.0 0.00043 20.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Ephrin_rec_like PF07699.11 001099575.1_32326001_1 - 0.013 15.1 6.1 0.033 13.8 6.1 1.6 1 0 0 1 1 1 0 Putative ephrin-receptor like SP2 PF03014.12 001099575.1_32326001_1 - 0.16 9.8 0.1 0.24 9.3 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 7tm_3 PF00003.20 001099579.1_32325001_1 - 9.6e-62 208.7 28.8 9.6e-62 208.7 28.8 1.6 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099579.1_32325001_1 - 1.3e-41 142.8 0.0 1.8e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099579.1_32325001_1 - 4.3e-18 64.9 13.4 7.7e-18 64.1 12.6 1.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099579.1_32325001_1 - 0.0015 18.2 5.4 0.0038 16.8 5.4 1.7 1 0 0 1 1 1 1 Putative ephrin-receptor like Peripla_BP_6 PF13458.4 001099579.1_32325001_1 - 0.0042 16.7 0.0 0.0065 16.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein SP2 PF03014.12 001099579.1_32325001_1 - 0.13 10.1 0.1 0.19 9.6 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 7tm_3 PF00003.20 001099580.1_32326001_1 - 5.2e-62 209.6 29.0 1e-61 208.6 29.0 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099580.1_32326001_1 - 2.1e-40 138.8 0.0 3.4e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099580.1_32326001_1 - 9.9e-19 66.9 13.2 2.4e-18 65.7 13.2 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099580.1_32326001_1 - 0.0051 16.4 5.3 0.014 15.0 5.3 1.7 1 0 0 1 1 1 1 Putative ephrin-receptor like 7tm_3 PF00003.20 001099581.1_32326001_1 - 1.9e-61 207.7 34.5 3.5e-61 206.8 34.5 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099581.1_32326001_1 - 2.4e-41 141.9 0.0 3.3e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099581.1_32326001_1 - 4.9e-18 64.7 12.1 1.2e-17 63.5 12.1 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099581.1_32326001_1 - 0.2 11.3 4.4 0.57 9.9 4.4 1.7 1 0 0 1 1 1 0 Putative ephrin-receptor like TNFR_c6 PF00020.16 001099581.1_32326001_1 - 4.1 7.8 9.1 3.9 7.8 1.6 2.7 1 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region 7tm_3 PF00003.20 001099582.1_32326001_1 - 1.6e-61 208.0 29.9 2.9e-61 207.1 29.9 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099582.1_32326001_1 - 5.1e-44 150.7 0.0 6.7e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099582.1_32326001_1 - 3.3e-17 62.0 13.6 3.3e-17 62.0 13.6 1.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR SP2 PF03014.12 001099582.1_32326001_1 - 0.084 10.8 0.1 0.15 9.9 0.1 1.3 1 0 0 1 1 1 0 Structural protein 2 Ephrin_rec_like PF07699.11 001099582.1_32326001_1 - 0.084 12.5 5.3 0.14 11.8 4.4 1.8 1 1 0 1 1 1 0 Putative ephrin-receptor like TNFR_c6 PF00020.16 001099582.1_32326001_1 - 6 7.2 9.0 22 5.5 3.9 2.8 1 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region 7tm_3 PF00003.20 001099583.1_32325001_1 - 1.2e-61 208.4 31.5 2.3e-61 207.4 31.5 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099583.1_32325001_1 - 5.9e-45 153.8 0.0 8.1e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099583.1_32325001_1 - 4e-16 58.6 13.6 1e-15 57.3 13.6 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099583.1_32325001_1 - 0.00034 20.3 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Ephrin_rec_like PF07699.11 001099583.1_32325001_1 - 0.016 14.8 5.9 0.045 13.4 5.9 1.7 1 0 0 1 1 1 0 Putative ephrin-receptor like TNFR_c6 PF00020.16 001099583.1_32325001_1 - 1.5 9.2 11.0 12 6.3 1.4 2.7 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region 7tm_3 PF00003.20 001099584.1_32325001_1 - 1.9e-62 211.0 30.6 3.9e-62 210.0 30.6 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099584.1_32325001_1 - 1.8e-45 155.4 0.0 2.5e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099584.1_32325001_1 - 9.7e-17 60.6 11.6 2.3e-16 59.4 11.6 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099584.1_32325001_1 - 0.00053 19.6 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Ephrin_rec_like PF07699.11 001099584.1_32325001_1 - 0.88 9.2 7.9 0.12 12.1 3.4 1.9 1 1 0 1 1 1 0 Putative ephrin-receptor like 7tm_3 PF00003.20 001099585.1_32325001_1 - 1.3e-61 208.3 29.1 2.2e-61 207.5 29.1 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099585.1_32325001_1 - 5.4e-44 150.6 0.0 7.6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099585.1_32325001_1 - 7.6e-16 57.7 13.7 7.6e-16 57.7 13.7 1.8 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099585.1_32325001_1 - 3.2e-05 23.7 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein SP2 PF03014.12 001099585.1_32325001_1 - 0.11 10.4 0.1 0.15 9.9 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 Ephrin_rec_like PF07699.11 001099585.1_32325001_1 - 0.32 10.6 10.0 0.15 11.7 7.4 1.8 1 1 0 1 1 1 0 Putative ephrin-receptor like TNFR_c6 PF00020.16 001099585.1_32325001_1 - 6.1 7.2 12.5 11 6.4 3.6 2.7 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region 7tm_3 PF00003.20 001099586.1_32326001_1 - 5.2e-60 203.0 28.6 5.2e-60 203.0 28.6 2.1 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099586.1_32326001_1 - 6.8e-45 153.6 0.0 1e-44 153.0 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099586.1_32326001_1 - 1.7e-19 69.4 13.8 4.1e-19 68.2 13.8 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099586.1_32326001_1 - 5.1e-05 23.0 0.0 7.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Ephrin_rec_like PF07699.11 001099586.1_32326001_1 - 0.053 13.2 5.9 0.14 11.8 5.9 1.7 1 0 0 1 1 1 0 Putative ephrin-receptor like 7tm_3 PF00003.20 001099587.1_32326001_1 - 1.4e-59 201.6 28.8 2.9e-59 200.6 28.8 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099587.1_32326001_1 - 1.4e-44 152.5 0.0 2.4e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099587.1_32326001_1 - 1.9e-19 69.2 13.8 4.1e-19 68.2 13.8 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001099587.1_32326001_1 - 0.0028 17.3 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein SP2 PF03014.12 001099587.1_32326001_1 - 0.19 9.6 0.1 0.29 9.0 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 Ephrin_rec_like PF07699.11 001099587.1_32326001_1 - 0.37 10.5 8.8 0.08 12.6 5.0 1.9 1 1 0 1 1 1 0 Putative ephrin-receptor like 7tm_3 PF00003.20 001099594.1_32326001_1 - 2.9e-65 220.2 29.3 5.8e-65 219.2 29.3 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099594.1_32326001_1 - 2.6e-52 178.0 0.0 3.2e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099594.1_32326001_1 - 1.1e-20 73.2 9.6 2.9e-20 71.8 9.6 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF3196 PF11428.6 001099594.1_32326001_1 - 0.058 12.8 0.1 0.091 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) Peripla_BP_6 PF13458.4 001099594.1_32326001_1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein 7tm_3 PF00003.20 001102427.1_32325001_1 - 2.1e-64 217.4 27.4 2.1e-64 217.4 27.4 1.9 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102427.1_32325001_1 - 1.1e-42 146.3 0.0 1.6e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102427.1_32325001_1 - 1.3e-18 66.6 10.6 1.3e-18 66.6 10.6 1.8 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR SP2 PF03014.12 001102427.1_32325001_1 - 0.13 10.2 0.1 0.19 9.6 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 Sucrose_synth PF00862.17 001102427.1_32325001_1 - 0.15 10.2 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Sucrose synthase DUF2873 PF11395.6 001102427.1_32325001_1 - 7.3 6.4 9.2 9.8 6.0 1.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) 7tm_3 PF00003.20 001102432.1_32326001_1 - 9.8e-61 205.4 28.9 9.8e-61 205.4 28.9 2.2 3 0 0 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102432.1_32326001_1 - 2.5e-44 151.7 0.0 3.4e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102432.1_32326001_1 - 8.6e-17 60.7 11.2 1.7e-16 59.7 11.2 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001102432.1_32326001_1 - 0.00041 20.0 0.0 0.0007 19.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.20 001102433.1_32325001_1 - 5.2e-60 203.0 27.8 5.2e-60 203.0 27.8 2.3 3 0 0 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102433.1_32325001_1 - 3.8e-45 154.4 0.0 5.2e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102433.1_32325001_1 - 7.6e-17 60.9 11.2 1.6e-16 59.9 11.2 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001102433.1_32325001_1 - 0.0014 18.2 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.20 001102434.1_32326001_1 - 5e-61 206.3 29.0 5e-61 206.3 29.0 2.6 3 0 0 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102434.1_32326001_1 - 3.9e-44 151.1 0.1 5.3e-44 150.6 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102434.1_32326001_1 - 8.9e-17 60.7 11.2 1.8e-16 59.7 11.2 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001102434.1_32326001_1 - 0.028 14.0 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein 7tm_3 PF00003.20 001102435.1_32326001_1 - 5.5e-62 209.5 30.8 1.2e-61 208.4 29.2 2.3 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102435.1_32326001_1 - 1.6e-45 155.6 0.1 2.2e-45 155.1 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102435.1_32326001_1 - 1.5e-17 63.2 11.8 3e-17 62.2 11.8 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001102435.1_32326001_1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.20 001102439.1_32325001_1 - 3.3e-66 223.3 20.9 5.7e-66 222.5 20.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102439.1_32325001_1 - 4.4e-50 170.6 0.1 6.6e-50 170.0 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102439.1_32325001_1 - 1.1e-16 60.4 12.5 2.1e-16 59.5 12.5 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001102439.1_32325001_1 - 0.059 13.0 8.1 0.16 11.6 8.1 1.7 1 0 0 1 1 1 0 Putative ephrin-receptor like 7tm_3 PF00003.20 001102448.1_32325001_1 - 2.2e-65 220.6 20.6 3.8e-65 219.8 20.6 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102448.1_32325001_1 - 1.9e-49 168.5 0.1 2.7e-49 168.1 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102448.1_32325001_1 - 3.3e-16 58.9 10.3 6.1e-16 58.0 10.3 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Metallophos_3 PF14582.4 001102448.1_32325001_1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily 7tm_3 PF00003.20 001102449.1_32325001_1 - 3.4e-62 210.1 24.3 6.3e-62 209.3 24.3 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102449.1_32325001_1 - 2.3e-52 178.1 0.0 3.2e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102449.1_32325001_1 - 2.8e-17 62.3 14.5 5.2e-17 61.4 14.5 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR 7tm_3 PF00003.20 001102452.1_32325001_1 - 1.5e-63 214.6 26.5 1.5e-63 214.6 26.5 1.6 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102452.1_32325001_1 - 3.8e-52 177.4 0.0 5.2e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102452.1_32325001_1 - 6.5e-18 64.3 16.3 6.5e-18 64.3 16.3 1.7 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR 7tm_3 PF00003.20 001102453.1_32325001_1 - 4.1e-64 216.4 26.7 1e-63 215.2 26.7 1.6 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001102453.1_32325001_1 - 1.1e-43 149.6 0.0 1.5e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001102453.1_32325001_1 - 8e-19 67.2 13.2 1.3e-18 66.5 12.6 1.8 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR SP2 PF03014.12 001102453.1_32325001_1 - 0.13 10.1 0.1 0.19 9.6 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 Ephrin_rec_like PF07699.11 001102453.1_32325001_1 - 0.16 11.6 5.2 0.46 10.2 5.2 1.8 1 0 0 1 1 1 0 Putative ephrin-receptor like C1-set PF07654.13 001324434.1_32323001_1 - 2.1e-11 44.0 0.0 5.1e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001324434.1_32323001_1 - 1.8e-07 30.8 0.2 2.6e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 ig PF00047.23 001324434.1_32323001_1 - 0.00032 20.7 0.0 0.00074 19.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001324434.1_32323001_1 - 0.0013 19.2 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain C1-set PF07654.13 001324429.1_32323001_1 - 5.2e-11 42.7 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001324429.1_32323001_1 - 1.7e-08 34.1 0.1 2.5e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 ig PF00047.23 001324429.1_32323001_1 - 9e-05 22.4 0.0 0.00039 20.4 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.4 001324429.1_32323001_1 - 0.0046 17.4 0.0 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain NUDIX_2 PF13869.4 001324429.1_32323001_1 - 0.045 13.2 0.1 0.072 12.5 0.1 1.3 1 0 0 1 1 1 0 Nucleotide hydrolase C1-set PF07654.13 001324433.1_32323001_1 - 4.3e-11 43.0 0.0 9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001324433.1_32323001_1 - 1.5e-10 40.8 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 ig PF00047.23 001324433.1_32323001_1 - 4.2e-05 23.5 0.0 0.00014 21.8 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.4 001324433.1_32323001_1 - 0.0063 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain MHC_I PF00129.16 001324431.1_32323001_1 - 6e-13 48.6 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001324431.1_32323001_1 - 3.6e-10 40.0 0.0 7.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.23 001324431.1_32323001_1 - 3.4e-05 23.8 0.0 8.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain IL17R_D_N PF16742.3 001324431.1_32323001_1 - 0.0052 16.8 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 N-terminus of interleukin 17 receptor D MHC_I_3 PF16497.3 001324431.1_32323001_1 - 0.014 14.7 0.4 0.022 14.1 0.4 1.2 1 0 0 1 1 1 0 MHC-I family domain C1-set PF07654.13 001324428.1_32323001_1 - 3.8e-12 46.4 0.0 7.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001324428.1_32323001_1 - 1e-09 38.1 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 ig PF00047.23 001324428.1_32323001_1 - 3e-05 24.0 0.0 6.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001324428.1_32323001_1 - 0.00069 19.8 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001324428.1_32323001_1 - 0.00092 19.7 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain MHC_I_3 PF16497.3 001324428.1_32323001_1 - 0.0095 15.3 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 1 MHC-I family domain C2-set_2 PF08205.10 001324428.1_32323001_1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain MHC_I PF00129.16 001324435.1_32322001_1 - 4.1e-21 75.2 0.4 5.4e-20 71.6 0.4 2.0 1 1 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I_3 PF16497.3 001324435.1_32322001_1 - 0.00036 19.9 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 MHC-I family domain MHC_I_2 PF14586.4 001324435.1_32322001_1 - 0.015 15.0 0.1 0.021 14.5 0.1 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 MHC_I PF00129.16 001324430.1_32323001_1 - 3e-18 65.9 0.5 4.1e-18 65.5 0.5 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001324430.1_32323001_1 - 6.2e-11 42.5 0.0 1.5e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001324430.1_32323001_1 - 0.0026 18.2 0.1 0.007 16.8 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Cytochrom_C_asm PF01578.18 001324430.1_32323001_1 - 0.03 14.0 0.4 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C assembly protein MHC_I_3 PF16497.3 001324430.1_32323001_1 - 0.038 13.3 5.0 0.071 12.4 4.8 1.6 1 1 0 1 1 1 0 MHC-I family domain Ig_2 PF13895.4 001324430.1_32323001_1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Mlf1IP PF10248.7 001324524.1_32324001_2 - 8.1e-63 211.3 2.5 1.3e-62 210.6 2.5 1.3 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Enolase_C PF00113.20 136930.1_32923120_1 - 5.7e-28 97.9 0.1 8.2e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_C PF00113.20 136930.1_32923120_2 - 6.6e-19 68.1 0.0 5.7e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Enolase, C-terminal TIM barrel domain MHC_I PF00129.16 001271005.1_32923001_2 - 1.2e-87 292.0 0.2 1.6e-87 291.6 0.2 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001271005.1_32923001_2 - 4.3e-15 55.8 0.0 7.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001271005.1_32923001_2 - 5.2e-05 23.7 0.2 0.057 13.9 0.0 2.5 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.23 001271005.1_32923001_2 - 0.0022 18.0 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001271005.1_32923001_2 - 0.0041 17.0 0.4 0.016 15.2 0.0 2.1 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 001271005.1_32923001_2 - 0.0048 17.1 0.0 0.0089 16.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.13 001271005.1_32923001_2 - 0.078 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A DUF4448 PF14610.4 001271005.1_32923001_2 - 0.083 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Cor1 PF04803.10 038297.2_32922120_1 - 6.3e-25 87.8 16.2 7.6e-25 87.5 16.2 1.1 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region DUF4168 PF13767.4 038297.2_32922120_1 - 0.019 16.0 2.0 0.019 16.0 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) Fe-S_biosyn PF01521.18 001242612.1_39721001_3 - 4.9e-20 71.7 0.0 5.8e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis RAWUL PF16207.3 001279832.1_39726001_2 - 2.2e-21 76.2 0.6 4.2e-21 75.2 0.6 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.4 001279832.1_39726001_2 - 8.6e-10 38.2 7.4 8.6e-10 38.2 7.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001279832.1_39726001_2 - 2.7e-08 33.4 8.1 2.7e-08 33.4 8.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001279832.1_39726001_2 - 3.5e-06 26.6 7.1 1e-05 25.1 7.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001279832.1_39726001_2 - 4.4e-06 26.7 7.0 4.4e-06 26.7 7.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.5 001279832.1_39726001_2 - 0.00015 21.8 3.6 0.00048 20.2 3.6 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.4 001279832.1_39726001_2 - 0.00028 20.6 7.2 0.00028 20.6 7.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.4 001279832.1_39726001_2 - 0.0014 18.3 5.8 0.0034 17.1 5.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 001279832.1_39726001_2 - 0.085 12.8 9.4 0.017 15.0 4.9 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.6 001279832.1_39726001_2 - 0.26 11.0 4.8 0.73 9.6 4.8 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1777 PF08648.10 001279832.1_39726001_2 - 0.76 9.9 25.9 0.05 13.7 19.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) zf-C3HC4_4 PF15227.4 001279832.1_39726001_2 - 0.81 9.8 15.9 0.22 11.6 9.9 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.12 001279832.1_39726001_2 - 1.4 8.5 6.5 5.1 6.7 6.5 2.0 1 0 0 1 1 1 0 P-11 zinc finger GTP_EFTU PF00009.25 001302529.1_39724001_2 - 4.5e-46 156.7 0.0 1e-45 155.6 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001302529.1_39724001_2 - 2.3e-30 105.0 2.5 9.5e-30 103.0 0.1 2.9 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001302529.1_39724001_2 - 1.4e-07 31.7 0.0 4.1e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001302529.1_39724001_2 - 0.0023 17.9 0.0 0.0087 16.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase CS PF04969.14 001246402.1_39724001_1 - 5.2e-09 36.9 0.0 9.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 CS domain Pkinase_C PF00433.22 001246402.1_39724001_1 - 1.8 9.2 5.3 4.3 8.0 5.3 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Rrn6 PF10214.7 001246402.1_39724001_2 - 0.77 8.0 4.8 1 7.6 4.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Histone PF00125.22 001098568.1_39723001_2 - 1.1e-53 181.0 1.7 1.6e-53 180.5 1.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001098568.1_39723001_2 - 0.0003 20.7 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.4 001098568.1_39723001_2 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.3 001098568.1_39723001_2 - 0.032 14.7 2.1 0.071 13.6 2.1 1.5 1 0 0 1 1 1 0 PCNA-associated factor ig PF00047.23 001105158.1_39722001_1 - 4.7e-06 26.6 0.0 6.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain 7tm_4 PF13853.4 001009111.1_39722001_1 - 3.4e-54 184.3 17.5 4.3e-54 184.0 17.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001009111.1_39722001_1 - 3.7e-18 65.6 20.6 8.5e-18 64.4 20.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001009116.1_39722001_1 - 3.2e-59 200.8 21.1 3.9e-59 200.6 21.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001009116.1_39722001_1 - 1.8e-23 83.0 25.4 8.9e-23 80.7 25.4 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001009116.1_39722001_1 - 4.6e-05 22.8 18.6 8.3e-05 21.9 18.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001009116.1_39722001_1 - 0.017 14.3 18.9 0.039 13.1 18.9 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Hormone_1 PF00103.18 001290361.1_39722001_1 - 4.6e-62 209.4 1.6 5.1e-62 209.3 1.6 1.0 1 0 0 1 1 1 1 Somatotropin hormone family SPAN-X PF07458.10 001009154.1_39721001_1 - 1e-38 131.5 3.3 1.2e-38 131.2 3.3 1.1 1 0 0 1 1 1 1 Sperm protein associated with nucleus, mapped to X chromosome DUF3749 PF12568.6 001009154.1_39721001_1 - 0.076 12.7 0.1 0.099 12.3 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ECH_1 PF00378.18 001246495.1_39724001_1 - 2.9e-35 121.7 0.4 5.3e-35 120.8 0.1 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.3 001246495.1_39724001_1 - 7e-20 71.7 1.4 1.6e-17 63.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Chromo PF00385.22 001246495.1_39724001_1 - 1.3e-17 63.3 1.6 2.5e-17 62.3 1.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mrr_cat PF04471.10 001246495.1_39724001_1 - 0.0016 18.3 4.7 0.63 10.0 0.0 4.2 3 1 1 4 4 4 1 Restriction endonuclease Tudor-knot PF11717.6 001246495.1_39724001_1 - 0.0034 17.1 2.6 0.0085 15.9 0.0 2.6 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.4 001246495.1_39724001_1 - 0.0047 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 UPF0167 PF03691.12 001246495.1_39724001_1 - 0.047 13.3 0.9 0.097 12.3 0.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-H2C2_2 PF13465.4 001246447.2_39724001_2 - 8.5e-69 225.0 86.9 4.3e-10 39.4 0.9 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.24 001246447.2_39724001_2 - 7.3e-62 202.4 93.6 1.2e-07 31.7 0.7 12.8 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001246447.2_39724001_2 - 4e-31 104.8 87.1 0.00082 19.9 1.8 12.3 12 0 0 12 12 12 10 C2H2-type zinc finger KRAB PF01352.25 001246447.2_39724001_2 - 2.6e-23 81.3 0.7 5.4e-23 80.3 0.7 1.6 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001246447.2_39724001_2 - 1.3e-14 53.6 76.5 0.00019 21.1 2.3 11.1 11 0 0 11 11 11 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001246447.2_39724001_2 - 1.8e-11 43.8 59.4 0.0027 17.7 2.2 8.0 5 2 4 9 9 9 6 Zinc ribbon domain zf-trcl PF13451.4 001246447.2_39724001_2 - 0.0033 17.1 48.8 0.5 10.2 1.8 10.8 10 1 0 10 10 10 3 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.3 001246447.2_39724001_2 - 0.0039 17.8 47.5 0.067 13.8 0.6 6.9 1 1 8 9 9 9 6 zinc-ribbon family zf-C2H2_jaz PF12171.6 001246447.2_39724001_2 - 0.01 16.0 57.3 0.069 13.4 0.7 10.2 10 0 0 10 10 10 3 Zinc-finger double-stranded RNA-binding CpXC PF14353.4 001246447.2_39724001_2 - 0.18 11.7 41.6 2.1 8.2 0.1 10.1 5 3 1 8 8 8 0 CpXC protein DUF3268 PF11672.6 001246447.2_39724001_2 - 0.46 10.7 40.2 0.43 10.8 1.0 6.5 3 1 7 10 10 10 0 zinc-finger-containing domain zinc_ribbon_9 PF14369.4 001246447.2_39724001_2 - 1.2 9.3 0.0 1.2 9.3 0.0 7.8 8 2 0 8 8 8 0 zinc-ribbon ADK_lid PF05191.12 001246447.2_39724001_2 - 1.3 9.0 33.7 3.9 7.4 0.7 8.6 3 3 5 8 8 8 0 Adenylate kinase, active site lid Alpha-amylase_C PF02806.16 001110157.1_39724001_1 - 4.5e-15 55.8 0.1 1e-14 54.6 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.22 001110157.1_39724001_1 - 3.3e-12 46.5 0.0 6.7e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3078 PF11276.6 001110157.1_39724001_1 - 0.09 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3078) Cpn60_TCP1 PF00118.22 001280170.1_39724001_2 - 1.6e-155 518.4 6.6 1.8e-155 518.2 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NEP PF10167.7 001197183.1_39722001_2 - 3.1e-38 130.0 0.1 4e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Serine_rich PF08824.8 001197183.1_39722001_2 - 0.12 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain FHIPEP PF00771.18 001197183.1_39722001_2 - 0.16 10.3 0.0 0.21 9.9 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family Hormone_1 PF00103.18 001008998.1_39722001_1 - 1.9e-62 210.7 1.9 2.2e-62 210.5 1.9 1.0 1 0 0 1 1 1 1 Somatotropin hormone family SWIM PF04434.15 001246483.1_39724001_1 - 3.9 7.1 5.9 2.3 7.9 0.4 2.5 2 0 0 2 2 2 0 SWIM zinc finger Peptidase_M24 PF00557.22 001246483.1_39724001_3 - 8.5e-25 87.5 0.2 1.2e-24 87.1 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TraC PF07820.10 001246483.1_39724001_3 - 0.041 14.1 3.7 0.12 12.6 2.2 2.5 2 0 0 2 2 2 0 TraC-like protein PH PF00169.27 001246486.1_39724001_1 - 1.7e-09 38.0 0.5 1.7e-09 38.0 0.5 1.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.4 001246486.1_39724001_1 - 0.00045 20.5 0.2 0.00076 19.7 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain LNP1 PF15419.4 001280233.1_39724001_3 - 3.9e-76 255.1 33.6 2.2e-44 151.7 20.1 2.2 1 1 1 2 2 2 2 Leukemia NUP98 fusion partner 1 PDZ_2 PF13180.4 001246400.1_39725001_3 - 9.4e-09 35.3 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.22 001246400.1_39725001_3 - 6.2e-05 23.1 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.12 001246400.1_39725001_3 - 0.00068 19.8 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Remorin_C PF03763.11 001246400.1_39725001_3 - 6.2 6.6 8.1 0.84 9.4 3.8 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region MHC_I PF00129.16 001045494.1_39723001_1 - 1.4e-25 89.8 1.3 2.4e-25 89.0 1.3 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001045494.1_39723001_1 - 6.4e-12 45.7 1.1 1.6e-11 44.4 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Piezo_RRas_bdg PF12166.6 001045494.1_39723001_1 - 0.015 14.5 0.4 0.022 13.9 0.4 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain ig PF00047.23 001045494.1_39723001_1 - 0.02 14.9 1.1 0.073 13.1 1.1 1.9 1 0 0 1 1 1 0 Immunoglobulin domain Trypsin PF00089.24 001135658.1_39722001_1 - 2.8e-69 233.2 0.0 3.3e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001135658.1_39722001_1 - 5.8e-07 30.4 0.0 9.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001135658.1_39722001_1 - 0.0023 18.2 0.3 0.01 16.1 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) DUF1929 PF09118.9 001135658.1_39722001_1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) ig PF00047.23 001160375.1_39723001_1 - 3.7e-30 103.8 0.0 4.3e-11 42.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001160375.1_39723001_1 - 8.2e-17 61.2 0.0 1.8e-06 28.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001160375.1_39723001_1 - 7.3e-15 55.2 0.0 5e-05 23.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001160375.1_39723001_1 - 8e-08 32.3 0.2 0.5 10.4 0.0 4.5 3 2 1 4 4 4 2 Immunoglobulin V-set domain GOLGA2L5 PF15070.4 001280298.1_39726001_1 - 1.1e-11 44.0 0.1 1.6e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 GOLGA2L5 PF15070.4 001280298.1_39726001_3 - 2.3e-46 158.6 60.0 4.4e-25 88.3 38.7 4.7 4 1 1 5 5 5 3 Putative golgin subfamily A member 2-like protein 5 IncA PF04156.12 001280298.1_39726001_3 - 0.00061 19.5 13.2 0.00061 19.5 13.2 3.4 2 1 1 3 3 3 1 IncA protein CENP-F_leu_zip PF10473.7 001280298.1_39726001_3 - 0.0018 18.2 14.6 0.0018 18.2 14.6 3.9 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.4 001280298.1_39726001_3 - 0.01 16.0 6.9 0.01 16.0 6.9 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.10 001280298.1_39726001_3 - 0.28 11.1 18.0 4.3 7.2 0.1 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_N PF02465.16 001280298.1_39726001_3 - 1.3 9.7 14.8 2 9.0 2.1 3.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF3584 PF12128.6 001280298.1_39726001_3 - 3.1 5.0 57.4 0.023 12.1 36.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1712 PF08217.9 001280309.1_39724001_2 - 1e-104 351.1 5.7 5.8e-95 318.9 0.2 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) RRM_1 PF00076.20 001246641.1_39724001_3 - 3.8e-34 116.2 0.1 1.9e-16 59.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001246641.1_39724001_3 - 1.7e-08 34.0 0.2 0.00016 21.2 0.1 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.21 001246641.1_39724001_3 - 1.7e-07 30.9 3.2 3.3e-07 29.9 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.3 001246641.1_39724001_3 - 7.3e-06 25.9 0.0 0.013 15.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.3 001246641.1_39724001_3 - 0.00011 21.8 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf-CCHC_3 PF13917.4 001246641.1_39724001_3 - 0.0025 17.6 0.3 0.0059 16.4 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Calcipressin PF04847.10 001246641.1_39724001_3 - 0.0044 16.6 0.1 3.1 7.4 0.0 2.3 1 1 1 2 2 2 2 Calcipressin DbpA PF03880.13 001246641.1_39724001_3 - 0.011 15.6 0.1 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain RNA_bind PF08675.9 001246641.1_39724001_3 - 0.031 14.2 0.0 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain zf-CCHC_5 PF14787.4 001246641.1_39724001_3 - 0.046 13.3 2.3 0.1 12.2 2.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.4 001246641.1_39724001_3 - 0.054 13.2 3.8 0.11 12.2 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle CompInhib_SCIN PF11546.6 001246641.1_39724001_3 - 4.8 7.3 5.9 8.5 6.5 2.9 2.3 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN DnaJ PF00226.29 001246646.1_39724001_1 - 4.7e-21 74.5 1.8 5e-15 55.2 0.2 2.5 2 0 0 2 2 2 2 DnaJ domain Ist1 PF03398.12 001280382.1_39725001_2 - 2.1e-61 206.5 3.8 2.7e-61 206.1 3.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Calreticulin PF00262.16 001280383.1_39725001_2 - 4.5e-158 525.8 7.2 4.5e-158 525.8 7.2 2.0 2 0 0 2 2 2 1 Calreticulin family CDC45 PF02724.12 001280383.1_39725001_2 - 0.0055 14.9 1.1 0.0074 14.5 1.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Paf1 PF03985.11 001280383.1_39725001_2 - 4.3 6.1 19.4 8.4 5.1 19.4 1.4 1 0 0 1 1 1 0 Paf1 S-antigen PF05756.9 001280383.1_39725001_2 - 6.5 6.9 10.2 3.7 7.7 5.5 2.6 2 0 0 2 2 2 0 S-antigen protein Glyco_transf_22 PF03901.15 001280391.1_39725001_2 - 1.9e-122 409.4 34.7 2.2e-122 409.1 34.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ATP-synt_F PF01990.15 001252592.1_39722001_1 - 2.1e-32 111.2 0.2 2.5e-32 110.9 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Arrestin_N PF00339.27 001271672.1_39726001_2 - 1.3e-23 83.6 0.1 2e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 001271672.1_39726001_2 - 2e-11 44.3 0.0 1.3e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MHC_II_beta PF00969.17 001279775.1_39722001_1 - 1.8e-38 130.4 1.0 2.8e-38 129.8 1.0 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001279775.1_39722001_1 - 4.3e-26 91.1 0.3 1.2e-25 89.7 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001279775.1_39722001_1 - 6.2e-05 23.4 0.1 0.00023 21.6 0.0 2.0 1 1 1 2 2 2 1 Immunoglobulin domain ig PF00047.23 001279775.1_39722001_1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.13 001279775.1_39722001_1 - 0.12 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Marek's disease glycoprotein A DUF202 PF02656.13 001279775.1_39722001_1 - 0.2 12.0 0.6 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) RasGEF PF00617.17 001280420.1_39725001_3 - 7.2e-44 149.9 0.0 1.6e-43 148.8 0.0 1.5 1 1 1 2 2 2 1 RasGEF domain Paf1 PF03985.11 001280426.2_39725001_2 - 5.7e-151 503.2 23.4 5.7e-151 503.2 23.4 2.2 1 1 1 2 2 2 1 Paf1 zf-H2C2_2 PF13465.4 001280443.1_39725001_1 - 6.7e-83 269.6 126.4 1.1e-08 35.0 1.2 16.2 16 0 0 16 16 16 13 Zinc-finger double domain zf-C2H2 PF00096.24 001280443.1_39725001_1 - 1.7e-32 109.9 140.7 0.0002 21.5 2.5 17.3 18 0 0 18 18 18 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280443.1_39725001_1 - 3.4e-28 95.8 136.4 0.00044 20.7 2.4 17.3 18 0 0 18 18 18 12 C2H2-type zinc finger KRAB PF01352.25 001280443.1_39725001_1 - 7.5e-25 86.2 0.3 1.2e-24 85.5 0.3 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001280443.1_39725001_1 - 5.6e-16 57.9 108.8 1.6e-05 24.6 1.5 15.2 14 1 0 14 14 14 11 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001280443.1_39725001_1 - 3.4e-05 23.8 86.4 0.016 15.2 1.5 10.7 7 2 5 12 12 12 8 Zinc ribbon domain zf-trcl PF13451.4 001280443.1_39725001_1 - 0.0007 19.3 64.4 6.4 6.6 3.6 12.3 9 3 2 11 11 11 5 Probable zinc-ribbon domain DUF3268 PF11672.6 001280443.1_39725001_1 - 0.013 15.7 53.8 0.42 10.8 3.4 6.7 1 1 8 9 9 9 0 zinc-finger-containing domain DEAD PF00270.27 001279842.1_39726001_3 - 3.5e-38 131.0 0.1 7.8e-38 129.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001279842.1_39726001_3 - 1e-27 96.6 0.3 6e-25 87.7 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.4 001279842.1_39726001_3 - 0.0075 16.4 0.5 0.036 14.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain MFS_1 PF07690.14 001279891.1_39725001_2 - 1.1e-44 152.7 33.3 4.3e-43 147.4 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 001279891.1_39725001_2 - 0.0012 17.7 20.9 0.23 10.1 3.6 4.1 4 0 0 4 4 4 4 Sugar (and other) transporter PTR2 PF00854.19 001279891.1_39725001_2 - 8.2 5.0 10.2 0.07 11.8 0.6 2.2 3 0 0 3 3 3 0 POT family Vert_HS_TF PF06546.9 001279921.1_39725001_2 - 3.9e-123 410.1 15.8 3.9e-123 410.1 15.8 1.6 2 0 0 2 2 2 1 Vertebrate heat shock transcription factor HSF_DNA-bind PF00447.15 001279921.1_39725001_2 - 6.2e-33 113.1 0.1 1.1e-32 112.4 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF247 PF03140.13 001279921.1_39725001_2 - 0.013 14.8 0.1 0.018 14.3 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function ZapB PF06005.10 001279921.1_39725001_2 - 0.039 14.3 3.4 0.085 13.2 3.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF2813 PF11398.6 001279921.1_39725001_2 - 0.055 12.6 1.5 0.08 12.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) HMMR_C PF15908.3 001279921.1_39725001_2 - 0.74 9.9 8.7 4.4 7.4 1.3 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal EMP70 PF02990.14 001280486.1_39725001_3 - 1.3e-157 525.4 3.0 2e-157 524.8 3.0 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 CorA PF01544.16 001280486.1_39725001_3 - 0.023 13.9 0.2 0.05 12.8 0.2 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sec1 PF00995.21 001280487.1_39724001_2 - 1.2e-119 401.0 0.0 1.4e-119 400.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pectinesterase PF01095.17 001280487.1_39724001_2 - 0.082 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase Cys_knot PF00007.20 001079831.1_39721001_2 - 9.5e-32 109.3 6.0 1.1e-31 109.1 6.0 1.1 1 0 0 1 1 1 1 Cystine-knot domain RRM_1 PF00076.20 001280513.1_39724001_3 - 3.3e-24 84.4 0.1 5.5e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001280513.1_39724001_3 - 0.0015 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.3 001280513.1_39724001_3 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif LRR_1 PF00560.31 001280518.1_39725001_3 - 0.034 14.4 0.7 73 4.3 0.0 4.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.5 001280518.1_39725001_3 - 0.11 12.9 11.0 7.8 6.9 1.0 5.1 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) RRM_1 PF00076.20 001098422.2_39723001_2 - 3.1e-36 122.9 0.1 1.5e-17 63.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 PF11627.6 001098422.2_39723001_2 - 5e-20 71.2 25.8 5e-20 71.2 25.8 6.0 2 1 2 4 4 4 1 Nuclear factor hnRNPA1 RRM_7 PF16367.3 001098422.2_39723001_2 - 1.9e-11 43.8 0.1 3.1e-06 27.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.4 001098422.2_39723001_2 - 8.5e-05 22.3 0.2 0.064 13.1 0.1 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RnaseA PF00074.18 001302404.1_39724001_2 - 2.2e-10 41.0 3.3 3.8e-10 40.2 3.3 1.3 1 0 0 1 1 1 1 Pancreatic ribonuclease Pkinase PF00069.23 001302406.1_39725001_3 - 3.8e-36 124.7 0.0 7e-36 123.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001302406.1_39725001_3 - 3.9e-24 85.2 0.0 4e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase GOLGA2L5 PF15070.4 001302414.1_39724001_1 - 1.5e-12 46.9 0.0 2e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 GOLGA2L5 PF15070.4 001302414.1_39724001_2 - 7.4e-31 107.4 0.1 6.5e-23 81.1 0.0 2.3 2 1 0 2 2 2 2 Putative golgin subfamily A member 2-like protein 5 GOLGA2L5 PF15070.4 001302414.1_39724001_3 - 1e-39 136.6 30.1 6.2e-39 134.0 30.2 1.8 1 1 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 IncA PF04156.12 001302414.1_39724001_3 - 0.0046 16.7 5.6 0.0083 15.8 5.6 1.5 1 0 0 1 1 1 1 IncA protein SurA_N PF09312.9 001302414.1_39724001_3 - 0.26 11.2 5.0 0.46 10.4 5.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain 7TM_transglut PF14402.4 001302414.1_39724001_3 - 0.49 9.4 5.3 0.63 9.0 5.3 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase ig PF00047.23 001104610.1_39723001_1 - 1e-16 60.7 0.0 3e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 001104610.1_39723001_1 - 1e-07 32.1 0.0 0.00018 21.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001104610.1_39723001_1 - 2e-07 31.4 0.1 0.0001 22.7 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.15 001104610.1_39723001_1 - 0.0017 18.3 0.2 0.61 10.1 0.0 2.9 2 1 0 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.3 001104610.1_39723001_1 - 0.045 14.0 0.2 3.4 8.0 0.0 3.1 2 2 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain MHC_II_beta PF00969.17 001302419.1_39722001_1 - 2.1e-37 127.0 0.8 3.2e-37 126.4 0.8 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001302419.1_39722001_1 - 7.6e-26 90.3 0.1 1.6e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001302419.1_39722001_1 - 3.5e-05 24.2 0.1 9.2e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001302419.1_39722001_1 - 0.00034 20.6 0.0 0.00065 19.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain MHC_I PF00129.16 001302419.1_39722001_1 - 0.048 13.1 0.1 0.077 12.4 0.1 1.4 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 DUF202 PF02656.13 001302419.1_39722001_1 - 0.06 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) RFX1_trans_act PF04589.11 001280147.1_39725001_1 - 9.2e-35 120.0 31.8 9.2e-35 120.0 31.8 2.7 2 1 0 2 2 2 1 RFX1 transcription activation region RFX_DNA_binding PF02257.13 001280147.1_39725001_1 - 9.3e-34 115.8 0.1 3e-33 114.2 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain HisKA PF00512.23 001280147.1_39725001_1 - 0.019 14.8 0.3 0.047 13.6 0.3 1.6 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Pox_D5 PF03288.14 001280147.1_39725001_1 - 0.067 13.6 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like DDE_Tnp_1_7 PF13843.4 001302429.1_39724001_3 - 9.3e-05 21.7 0.0 0.00014 21.2 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DUF1601 PF07671.9 001302429.1_39724001_3 - 0.11 12.2 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DUF4501 PF14946.4 001302432.1_39724001_2 - 2.7e-87 291.3 0.1 3.8e-87 290.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) COesterase PF00135.26 001302438.1_39724001_1 - 1.1e-140 469.8 0.0 1.4e-140 469.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001302438.1_39724001_1 - 4.2e-10 39.7 1.9 2e-09 37.5 1.6 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.7 001302438.1_39724001_1 - 0.0058 15.4 0.0 0.029 13.1 0.0 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase Esterase PF00756.18 001302438.1_39724001_1 - 0.013 15.0 0.6 0.049 13.1 0.7 1.8 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.19 001302438.1_39724001_1 - 0.038 13.3 0.1 0.071 12.4 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family RPN7 PF10602.7 001320164.1_39724001_2 - 1.2e-73 246.4 0.7 1.9e-73 245.7 0.7 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.25 001320164.1_39724001_2 - 6.4e-17 61.8 0.9 1.8e-16 60.4 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.15 001320164.1_39724001_2 - 0.033 14.2 4.3 0.21 11.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.4 001320164.1_39724001_2 - 0.038 13.6 0.7 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.26 001320164.1_39724001_2 - 0.24 11.2 0.1 0.24 11.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Interferon PF00143.17 001242707.1_37622001_1 - 7.3e-53 178.9 1.4 8.9e-53 178.6 1.4 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain TilS PF09179.9 001242707.1_37622001_3 - 0.34 11.3 0.3 0.34 11.3 0.3 1.9 2 0 0 2 2 2 0 TilS substrate binding domain Insulin PF00049.16 001122689.1_37621001_1 - 1.9e-06 28.6 2.8 3.4e-05 24.6 2.8 2.2 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001122689.1_37621001_1 - 0.015 15.1 6.1 1.1 9.2 0.2 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Interferon PF00143.17 001242721.1_37622001_1 - 1.6e-55 187.6 1.3 1.9e-55 187.3 1.3 1.1 1 0 0 1 1 1 1 Interferon alpha/beta domain DUF3489 PF11994.6 001242721.1_37622001_1 - 0.037 14.0 0.0 2.8 7.9 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3489) IL3 PF02059.13 001291854.1_37622001_1 - 0.023 14.7 1.4 0.095 12.7 0.3 2.0 1 1 1 2 2 2 0 Interleukin-3 Semenogelin PF05474.9 001169025.1_40426001_1 - 0 1655.7 163.4 1.6e-268 892.0 72.2 3.0 1 1 2 3 3 3 3 Semenogelin HCV_NS4a PF01006.18 001169025.1_40426001_1 - 1.6e-07 30.8 0.0 23 4.7 0.0 6.5 6 0 0 6 6 6 2 Hepatitis C virus non-structural protein NS4a DUF2951 PF11166.6 001169025.1_40426001_1 - 10 6.3 19.6 73 3.5 0.0 6.8 3 3 4 7 7 7 0 Protein of unknown function (DUF2951) DUF2589 PF11655.6 001169025.1_40426001_2 - 0.0011 19.2 13.6 32 4.7 1.0 6.7 5 1 2 7 7 7 6 Protein of unknown function (DUF2589) Semenogelin PF05474.9 001169022.1_40426001_1 - 0 1193.0 141.0 5.4e-257 853.9 81.7 2.0 1 1 1 2 2 2 2 Semenogelin SpoU_methylas_C PF12105.6 001169022.1_40426001_2 - 0.0014 18.1 0.0 5.5 6.7 0.0 4.6 5 0 0 5 5 5 1 SpoU, rRNA methylase, C-terminal ADK_lid PF05191.12 001169022.1_40426001_2 - 0.0016 18.3 0.3 3.4e+02 1.2 0.0 6.3 7 0 0 7 7 7 0 Adenylate kinase, active site lid GYF PF02213.14 001169022.1_40426001_2 - 0.0054 16.3 1.9 3.2e+02 1.0 0.0 6.3 7 0 0 7 7 7 0 GYF domain FlgH PF02107.14 001169022.1_40426001_2 - 0.0059 16.1 1.4 26 4.3 0.0 5.1 6 0 0 6 6 6 1 Flagellar L-ring protein MHC_I PF00129.16 001246245.1_49824001_2 - 2.7e-85 284.3 0.5 3.6e-85 283.9 0.5 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001246245.1_49824001_2 - 9.7e-17 61.1 0.0 1.9e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001246245.1_49824001_2 - 2.2e-13 49.7 6.9 5.4e-13 48.5 6.9 1.6 1 0 0 1 1 1 1 MHC_I C-terminus ig PF00047.23 001246245.1_49824001_2 - 0.00073 19.5 0.1 0.0024 17.9 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.10 001246245.1_49824001_2 - 0.0061 16.5 2.2 0.0076 16.2 0.3 2.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 001246245.1_49824001_2 - 0.069 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain DUF1822 PF08852.9 001246245.1_49824001_2 - 0.087 11.7 0.6 2.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) P12 PF12669.5 001246245.1_49824001_2 - 0.67 10.3 2.0 1.2 9.5 2.0 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Telomerase_RBD PF12009.6 001282465.1_37629001_3 - 6.8e-40 136.1 1.2 1.7e-39 134.9 1.2 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.25 001282465.1_37629001_3 - 2.8e-14 53.1 0.2 8.8e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) HMG_box PF00505.17 024023.1_45724120_1 - 5.2e-21 74.7 12.0 1.5e-18 66.8 1.7 3.6 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.8 024023.1_45724120_1 - 4.4e-11 43.1 7.2 1.9e-08 34.6 0.2 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box_2 PF09011.8 024023.1_45724120_3 - 3e-15 56.4 1.5 5.1e-15 55.7 1.5 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.17 024023.1_45724120_3 - 0.0013 18.9 0.7 0.0026 18.0 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box GBP_PSP PF02425.13 037685.1_43529120_3 - 0.71 9.4 2.8 19 4.9 2.4 2.8 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide P33MONOX PF15302.4 045552.1_49822120_3 - 9.6e-13 48.3 0.1 1.4e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 P33 mono-oxygenase RIIa PF02197.15 001127616.1_37622001_1 - 3e-14 52.2 0.1 4.6e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit IQ PF00612.25 001127616.1_37622001_1 - 1.7e-06 27.2 0.0 2.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif WAP PF00095.19 001101664.1_37622001_1 - 1.9e-20 72.8 38.2 1.8e-11 44.1 13.9 2.5 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pribosyltran PF00156.25 001242751.1_37623001_1 - 6.5e-22 77.6 0.0 8.9e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Trypsin PF00089.24 001127623.1_37623001_1 - 4.9e-54 183.3 0.5 6.8e-54 182.9 0.5 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001127623.1_37623001_1 - 6.9e-07 29.5 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001127623.1_37623001_1 - 7.2e-05 23.6 0.1 0.00013 22.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ldh_1_N PF00056.21 001127620.1_37623001_2 - 9.6e-51 171.4 0.6 1.4e-50 171.0 0.6 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001127620.1_37623001_2 - 2.2e-24 86.1 0.0 4.5e-24 85.1 0.0 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.14 001127620.1_37623001_2 - 0.011 15.2 0.4 0.039 13.4 0.0 2.0 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Pyr_redox_2 PF07992.12 001127620.1_37623001_2 - 0.13 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trypsin PF00089.24 001127614.1_37624001_1 - 5.5e-67 225.7 0.2 8.2e-67 225.1 0.2 1.3 1 0 0 1 1 1 1 Trypsin Gla PF00594.18 001127614.1_37624001_1 - 1.4e-20 73.1 11.0 1.4e-20 73.1 11.0 1.8 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.4 001127614.1_37624001_1 - 1.6e-10 41.0 7.4 1.6e-10 41.0 7.4 3.2 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site EGF PF00008.25 001127614.1_37624001_1 - 3.5e-07 30.3 6.6 3.5e-07 30.3 6.6 3.7 3 0 0 3 3 3 2 EGF-like domain DUF1986 PF09342.9 001127614.1_37624001_1 - 0.00031 21.0 0.0 0.00056 20.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) hEGF PF12661.5 001127614.1_37624001_1 - 0.0007 20.0 2.8 0.0007 20.0 2.8 4.6 5 1 0 5 5 3 2 Human growth factor-like EGF cEGF PF12662.5 001127614.1_37624001_1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 3.5 4 0 0 4 4 4 2 Complement Clr-like EGF-like Trypsin_2 PF13365.4 001127614.1_37624001_1 - 0.0017 19.1 0.0 0.0047 17.7 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF_2 PF07974.11 001127614.1_37624001_1 - 0.005 17.0 10.5 0.005 17.0 10.5 3.8 4 0 0 4 4 2 1 EGF-like domain EGF_3 PF12947.5 001127614.1_37624001_1 - 0.18 11.9 22.2 0.082 13.0 4.2 3.0 2 0 0 2 2 2 0 EGF domain Laminin_EGF PF00053.22 001127614.1_37624001_1 - 7.6 6.6 22.1 2.1 8.4 7.9 3.2 1 1 1 2 2 2 0 Laminin EGF domain EphA2_TM PF14575.4 001246850.1_37622001_2 - 0.0052 17.4 0.0 0.0088 16.7 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TAP35_44 PF07265.9 001246850.1_37622001_2 - 5.1 7.0 6.7 50 3.8 6.7 2.3 1 1 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 UCR_6-4kD PF08997.8 001190803.1_37621001_1 - 1.6e-29 101.5 1.1 2.3e-29 100.9 1.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.7 001190803.1_37621001_1 - 0.088 12.7 1.9 0.28 11.1 1.9 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TMEM189_B_dmain PF10520.7 001205118.1_37622001_1 - 2.2e-78 262.3 2.4 2.2e-78 262.3 2.4 1.5 2 0 0 2 2 2 1 B domain of TMEM189, localisation domain MARVEL PF01284.21 001205118.1_37622001_1 - 0.027 14.4 0.4 4 7.3 0.1 2.1 2 0 0 2 2 2 0 Membrane-associating domain UCMA PF17085.3 001166046.1_37621001_1 - 2.5e-69 231.3 7.9 2.8e-69 231.2 7.9 1.0 1 0 0 1 1 1 1 Unique cartilage matrix associated protein C_Hendra PF16821.3 001166046.1_37621001_1 - 0.019 14.7 5.0 0.032 14.0 4.9 1.4 1 1 0 1 1 1 0 C protein from hendra and measles viruses Selenoprotein_S PF06936.9 001166046.1_37621001_1 - 0.029 14.0 14.6 0.034 13.8 13.4 1.6 1 1 1 2 2 2 0 Selenoprotein S (SelS) Neur_chan_memb PF02932.14 001166046.1_37621001_1 - 0.1 12.5 0.4 0.11 12.3 0.4 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNase_H2_suC PF08615.9 001166046.1_37621001_1 - 0.12 12.5 5.4 0.15 12.1 5.4 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Folate_carrier PF01770.16 001166046.1_37621001_1 - 3.1 6.3 3.9 3 6.4 3.4 1.3 1 1 0 1 1 1 0 Reduced folate carrier Paralemmin PF03285.13 001204207.1_37623001_1 - 3.1e-112 375.1 17.5 3.1e-112 375.1 17.5 2.0 2 0 0 2 2 2 1 Paralemmin ERM PF00769.17 001204207.1_37623001_1 - 0.076 12.7 25.0 0.029 14.1 17.9 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.17 001204207.1_37623001_1 - 0.39 8.4 6.0 0.59 7.8 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.9 001204207.1_37623001_1 - 2 6.1 5.4 2.9 5.6 5.4 1.2 1 0 0 1 1 1 0 Prominin Vitellogenin_N PF01347.20 001242755.1_37629001_1 - 4.4e-83 279.6 6.6 1e-82 278.4 6.6 1.7 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.9 001242755.1_37629001_1 - 8.5e-78 261.6 0.1 8.5e-78 261.6 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1943) DUF1081 PF06448.9 001242755.1_37629001_1 - 2.5e-38 130.8 0.1 6.8e-37 126.2 0.1 3.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1081) ApoB100_C PF12491.6 001242755.1_37629001_1 - 2.1e-23 81.9 1.5 2.1e-23 81.9 1.5 2.9 2 0 0 2 2 2 1 Apolipoprotein B100 C terminal Ribosom_S12_S23 PF00164.23 001242755.1_37629001_1 - 0.012 15.1 0.1 0.042 13.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S12/S23 HEAT_2 PF13646.4 001242755.1_37629001_1 - 0.037 14.3 0.0 0.29 11.4 0.1 2.6 2 0 0 2 2 2 0 HEAT repeats Imm30 PF15565.4 001242755.1_37629001_1 - 0.055 13.4 2.6 1 9.4 0.2 4.1 3 0 0 3 3 3 0 Immunity protein 30 DUF668 PF05003.10 001242755.1_37629001_1 - 0.11 12.8 2.1 2.4 8.5 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF668) GARP PF16731.3 001242755.1_37629001_1 - 2.3 7.7 5.6 0.68 9.5 1.0 2.5 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma BLOC1S3 PF15753.3 001242755.1_37629001_1 - 8.4 6.3 7.9 0.61 10.1 0.6 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 NDK PF00334.17 001204752.1_37622001_2 - 5.1e-54 181.8 0.0 5.8e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.17 001204753.1_37622001_2 - 4.7e-56 188.4 0.0 5.5e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase IDO PF01231.16 001242723.1_37623001_2 - 5.8e-119 397.6 0.0 6.7e-119 397.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase IL32 PF15225.4 001242723.1_37623001_2 - 0.0014 18.8 0.2 0.008 16.4 0.1 2.1 2 0 0 2 2 2 1 Interleukin 32 DUF1864 PF08933.9 001242723.1_37623001_2 - 0.059 12.0 0.1 0.19 10.3 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1864) zf-C2H2 PF00096.24 001242756.1_37623001_1 - 8.1e-15 54.2 60.1 0.019 15.3 0.2 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001242756.1_37623001_1 - 4e-12 45.7 60.8 0.049 14.3 0.9 9.8 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001242756.1_37623001_1 - 4.1e-11 42.7 45.6 5.4e-05 23.3 0.1 9.7 9 0 0 9 9 9 5 Zinc-finger double domain zf-H2C2_5 PF13909.4 001242756.1_37623001_1 - 7.8e-11 41.4 35.3 0.00037 20.1 0.5 6.7 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.3 001242756.1_37623001_1 - 0.014 16.0 29.0 0.093 13.4 1.7 5.1 3 1 2 5 5 5 0 zinc-ribbon family CarbpepA_inh PF02977.13 001242756.1_37623001_1 - 0.12 12.1 8.8 1.7 8.4 0.0 4.3 4 0 0 4 4 4 0 Carboxypeptidase A inhibitor zf-C2H2_8 PF15909.3 001242756.1_37623001_1 - 0.99 9.6 31.9 1.7 8.9 4.9 5.4 1 1 1 4 4 4 0 C2H2-type zinc ribbon DZR PF12773.5 001242756.1_37623001_1 - 4.6 7.2 25.0 1.7 8.6 0.9 5.1 3 2 1 4 4 4 0 Double zinc ribbon zf-C2H2_2 PF12756.5 001242756.1_37623001_1 - 6.4 7.0 45.4 2.6 8.3 8.0 5.8 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) ST7 PF04184.10 001242741.1_37624001_1 - 0 1039.0 0.1 0 1038.8 0.1 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.4 001242741.1_37624001_1 - 0.00056 20.2 0.0 0.0025 18.2 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.15 001242741.1_37624001_1 - 0.025 14.5 2.1 4 7.7 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.18 001242741.1_37624001_1 - 0.049 13.4 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_19 PF14559.4 001242741.1_37624001_1 - 0.085 13.2 3.7 0.34 11.3 0.2 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.26 001242741.1_37624001_1 - 0.21 11.3 2.3 27 4.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.4 001242741.1_37624001_1 - 8.8 7.3 7.2 58 4.8 0.1 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat G-gamma PF00631.20 001205010.1_37622001_1 - 4.8e-15 55.2 0.1 7.3e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 GGL domain WAP PF00095.19 001101665.1_37622001_1 - 1e-21 76.9 70.1 6.2e-08 32.8 17.3 3.3 4 0 0 4 4 4 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' Keratin_B2 PF01500.15 001159761.1_39521001_1 - 3e-58 196.3 94.1 4.2e-55 186.1 94.1 2.6 1 1 0 1 1 1 1 Keratin, high sulfur B2 protein Keratin_B2_2 PF13885.4 001159761.1_39521001_1 - 2.6e-09 36.7 126.9 0.00017 21.4 40.8 4.3 2 2 2 4 4 4 4 Keratin, high sulfur B2 protein Late_protein_L2 PF00513.16 001159761.1_39521001_1 - 0.1 11.4 0.2 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 Late Protein L2 Cadherin PF00028.15 001013010.2_39728001_2 - 1.4e-80 265.7 0.0 8.9e-17 61.2 0.0 6.2 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.10 001013010.2_39728001_2 - 8.1e-39 131.2 0.3 1.5e-35 120.7 0.1 3.6 4 0 0 4 4 4 2 Cadherin-like Cadherin_C_2 PF16492.3 001013010.2_39728001_2 - 1.7e-27 95.9 0.8 3.8e-27 94.8 0.8 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Cadherin_3 PF16184.3 001013010.2_39728001_2 - 4.9e-07 29.6 2.6 0.0044 16.9 0.0 4.4 4 0 0 4 4 4 2 Cadherin-like SPR1 PF15356.4 001242742.1_37621001_1 - 5.8e-39 133.0 56.6 6.6e-39 132.8 56.6 1.0 1 0 0 1 1 1 1 Psoriasis susceptibility locus 2 Trypsin PF00089.24 001202501.1_43523001_3 - 5.9e-69 232.1 0.0 6.9e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001202501.1_43523001_3 - 9.1e-07 29.7 0.0 1.5e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001202501.1_43523001_3 - 0.0017 18.6 0.6 0.0058 16.9 0.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Humanin PF15040.4 001193578.1_39724001_3 - 1.4e-15 56.3 0.1 2.4e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Humanin family EF-hand_1 PF00036.30 001242743.1_37621001_1 - 0.00011 21.4 1.8 0.015 14.7 0.7 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 001242743.1_37621001_1 - 0.00025 21.3 0.1 0.00042 20.6 0.1 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.4 001242743.1_37621001_1 - 0.001 18.7 0.9 0.007 16.1 0.3 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.4 001242743.1_37621001_1 - 0.008 15.5 0.6 0.04 13.3 0.5 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.4 001242743.1_37621001_1 - 0.04 13.6 0.6 0.8 9.4 0.3 2.2 2 0 0 2 2 2 0 EF-hand domain pair TOPRIM_C PF16898.3 001242743.1_37621001_1 - 0.061 13.5 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM ECH_2 PF16113.3 001133908.1_43525001_1 - 0.00011 21.8 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.3 001133908.1_43525001_2 - 2.6e-117 392.0 0.0 3.4e-117 391.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.18 001133908.1_43525001_2 - 5.4e-30 104.4 0.0 2.6e-29 102.2 0.0 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase PRNT PF15174.4 038114.1_43525120_1 - 4.4e-34 116.1 4.0 9e-34 115.1 4.0 1.6 1 0 0 1 1 1 1 Prion-related protein testis-specific Neuropeptide_S PF14993.4 001163113.1_37921001_1 - 2.5e-35 120.0 0.2 2.5e-35 120.0 0.2 1.5 2 0 0 2 2 2 1 Neuropeptide S precursor protein 7tm_1 PF00001.19 001160280.1_37923001_1 - 7.5e-49 166.2 17.3 9.4e-49 165.9 17.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001160280.1_37923001_1 - 3.8e-07 29.6 14.3 5.6e-07 29.1 14.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001160280.1_37923001_1 - 0.00028 20.2 9.9 0.00028 20.2 9.9 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4790 PF16037.3 001160280.1_37923001_1 - 0.061 13.7 0.0 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) Piezo_RRas_bdg PF12166.6 001160280.1_37923001_1 - 0.13 11.4 1.0 9.3 5.2 0.2 2.2 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain DUF3262 PF11660.6 001160280.1_37923001_1 - 1.9 8.8 7.4 7.1 6.9 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3262) DUF2975 PF11188.6 001160280.1_37923001_1 - 2.5 7.9 14.6 0.019 14.7 3.1 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2975) V1R PF03402.12 001167356.1_37922001_1 - 1.1e-34 120.1 17.9 1.5e-34 119.7 17.9 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167356.1_37922001_1 - 1.4e-15 57.1 28.6 1.7e-15 56.8 28.6 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001167356.1_37922001_1 - 4.5e-05 22.7 18.6 7.1e-05 22.0 18.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001167219.1_37922001_1 - 2.6e-64 217.3 28.6 3.1e-64 217.0 28.6 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167219.1_37922001_1 - 0.00058 18.9 35.7 0.00093 18.3 35.7 1.3 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167192.1_37922001_1 - 1.6e-94 316.3 23.4 1.9e-94 316.1 23.4 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167192.1_37922001_1 - 1.1e-07 31.1 23.8 1.5e-07 30.7 23.8 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF1106 PF06523.9 001167192.1_37922001_1 - 0.33 10.9 0.0 0.33 10.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1106) DUF2157 PF09925.7 001167192.1_37922001_1 - 5.4 6.7 8.7 3.5 7.3 1.7 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) V1R PF03402.12 001167232.1_37922001_1 - 4.3e-92 308.4 24.9 5.1e-92 308.1 24.9 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167232.1_37922001_1 - 1.5e-09 37.3 21.1 2e-09 36.8 21.1 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DDDD PF10161.7 001167232.1_37922001_1 - 0.13 11.9 0.2 0.97 9.1 0.0 2.3 2 0 0 2 2 2 0 Putative mitochondrial precursor protein V1R PF03402.12 001167335.1_37922001_1 - 7.5e-93 310.8 23.5 1.3e-92 310.0 21.5 1.9 1 1 1 2 2 2 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167335.1_37922001_1 - 0.061 12.4 14.6 0.096 11.8 14.6 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Cytochrom_B561 PF03188.14 001167335.1_37922001_1 - 6 6.9 14.4 0.31 11.0 2.4 3.4 2 2 1 4 4 4 0 Eukaryotic cytochrome b561 V1R PF03402.12 001167312.1_37922001_1 - 9.5e-28 97.4 15.8 1.2e-27 97.0 15.8 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167312.1_37922001_1 - 1.3e-08 34.2 22.9 1.4e-08 34.1 22.9 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167324.1_37922001_1 - 1.9e-93 312.8 23.3 2.3e-93 312.5 23.3 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167324.1_37922001_1 - 2.9e-06 26.5 25.0 4.1e-06 26.0 25.0 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF3989 PF13150.4 001167324.1_37922001_1 - 0.074 12.7 0.0 0.32 10.6 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) bPH_3 PF14470.4 001167324.1_37922001_1 - 0.079 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial PH domain DDDD PF10161.7 001167324.1_37922001_1 - 0.16 11.6 0.1 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Putative mitochondrial precursor protein DUF2157 PF09925.7 001167324.1_37922001_1 - 2.7 7.7 8.5 4.5 6.9 2.9 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) V1R PF03402.12 001167289.1_37922001_1 - 7.3e-82 274.8 22.1 9.5e-82 274.4 22.1 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167289.1_37922001_1 - 9.5e-08 31.4 22.6 1.3e-07 30.9 22.6 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) BatA PF07584.9 001167289.1_37922001_1 - 1 9.7 6.1 0.75 10.1 0.1 3.0 2 1 0 2 2 2 0 Aerotolerance regulator N-terminal V1R PF03402.12 001167308.1_37922001_1 - 4.6e-92 308.3 20.5 6.4e-92 307.8 20.5 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167308.1_37922001_1 - 0.0059 15.7 16.8 0.0086 15.2 16.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001167347.1_37922001_1 - 6.8e-96 320.8 23.7 8.1e-96 320.6 23.7 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167347.1_37922001_1 - 2.8e-06 26.5 22.6 3.9e-06 26.1 22.6 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167317.1_37922001_1 - 1.5e-88 296.7 20.0 2.5e-88 296.0 20.0 1.3 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R BatA PF07584.9 001167317.1_37922001_1 - 0.0042 17.3 3.2 0.89 9.8 0.3 2.7 2 0 0 2 2 2 2 Aerotolerance regulator N-terminal 7tm_1 PF00001.19 001167317.1_37922001_1 - 0.0049 16.0 18.6 0.0069 15.5 18.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001167340.1_37922001_1 - 9.8e-91 303.9 15.2 1.3e-90 303.5 15.2 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167340.1_37922001_1 - 8.9e-07 28.2 15.3 1.7e-06 27.2 15.3 1.4 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001167340.1_37922001_1 - 0.0025 17.0 10.1 0.0039 16.3 10.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BatA PF07584.9 001167340.1_37922001_1 - 0.019 15.2 2.1 2.2 8.6 0.1 2.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal MotB_plug PF13677.4 001167340.1_37922001_1 - 0.72 9.4 10.8 0.21 11.0 4.3 2.6 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB Spot_14 PF07084.10 001198981.1_37921001_1 - 6.4e-54 182.1 0.4 7.2e-54 181.9 0.4 1.0 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 V1R PF03402.12 001167258.1_37922001_1 - 8.5e-89 297.5 22.1 8.5e-89 297.5 22.1 1.8 2 0 0 2 2 2 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167258.1_37922001_1 - 4.9e-05 22.6 16.2 9e-05 21.7 16.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CRF PF00473.15 001199007.1_37922001_1 - 3.5e-16 58.9 1.1 3.5e-16 58.9 1.1 1.6 2 0 0 2 2 2 1 Corticotropin-releasing factor family V1R PF03402.12 001167200.1_37922001_1 - 4.3e-90 301.8 26.4 5.2e-90 301.5 26.4 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167200.1_37922001_1 - 9.6e-07 28.1 24.5 1.3e-06 27.7 24.5 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Ycf9 PF01737.15 001167200.1_37922001_1 - 6.5 6.6 11.4 5.1 6.9 0.5 3.4 3 0 0 3 3 3 0 YCF9 V1R PF03402.12 001167292.1_37922001_1 - 8.1e-87 291.1 15.3 1.1e-86 290.6 15.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167292.1_37922001_1 - 0.0021 17.2 12.9 0.0021 17.2 12.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BatA PF07584.9 001167292.1_37922001_1 - 0.022 15.0 2.9 2.2 8.6 0.2 2.7 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal V1R PF03402.12 001167295.1_37922001_1 - 2.9e-27 95.8 18.8 3.6e-27 95.5 18.8 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167295.1_37922001_1 - 1.2e-12 47.5 18.0 1.4e-12 47.2 18.0 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF3810 PF12725.5 001167295.1_37922001_1 - 4.1 6.5 7.1 0.35 10.0 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) V1R PF03402.12 001167322.1_37922001_1 - 2e-86 289.8 17.1 3e-86 289.2 17.1 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R V1R PF03402.12 001167197.1_37922001_1 - 1.8e-95 319.4 24.7 2.2e-95 319.1 24.7 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167197.1_37922001_1 - 1.2e-07 31.0 21.4 1.6e-07 30.6 21.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DDDD PF10161.7 001167197.1_37922001_1 - 0.17 11.5 0.2 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Cpta_toxin PF07254.10 001167197.1_37922001_1 - 6.8 6.5 7.0 2 8.3 0.5 2.8 3 0 0 3 3 3 0 Membrane-bound toxin component of toxin-antitoxin system V1R PF03402.12 001167334.1_37922001_1 - 4.1e-83 278.9 17.9 4.1e-83 278.9 17.9 1.8 2 0 0 2 2 2 1 Vomeronasal organ pheromone receptor family, V1R BatA PF07584.9 001167334.1_37922001_1 - 0.13 12.5 7.7 0.83 9.9 0.0 2.9 3 1 0 3 3 3 0 Aerotolerance regulator N-terminal V1R PF03402.12 001167206.1_37922001_1 - 6.9e-91 304.4 18.5 9.3e-91 304.0 18.5 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167206.1_37922001_1 - 0.0068 15.5 14.7 0.0094 15.1 14.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BatA PF07584.9 001167206.1_37922001_1 - 0.0073 16.5 3.7 0.79 10.0 0.1 2.8 2 1 0 2 2 2 2 Aerotolerance regulator N-terminal DUF3290 PF11694.6 001167206.1_37922001_1 - 1.3 8.9 3.6 0.8 9.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) V1R PF03402.12 001167314.1_37922001_1 - 5.4e-90 301.5 18.9 7.7e-90 301.0 18.9 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167314.1_37922001_1 - 0.0036 16.4 11.7 0.0057 15.8 11.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BatA PF07584.9 001167314.1_37922001_1 - 0.39 11.0 2.8 1.8 8.9 0.2 2.6 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal V1R PF03402.12 001167214.1_37922001_1 - 7.7e-89 297.7 15.1 1.1e-88 297.2 15.1 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167214.1_37922001_1 - 0.00018 20.7 11.3 0.00026 20.2 11.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BatA PF07584.9 001167214.1_37922001_1 - 0.0073 16.5 2.4 1 9.7 0.1 2.7 2 0 0 2 2 2 2 Aerotolerance regulator N-terminal fn2 PF00040.17 001082047.1_37925001_3 - 4.8e-28 97.0 20.9 8.1e-16 57.9 4.3 2.4 2 0 0 2 2 2 2 Fibronectin type II domain V1R PF03402.12 001167208.1_37922001_1 - 5.1e-28 98.3 19.9 6.2e-28 98.0 19.9 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167208.1_37922001_1 - 1.4e-10 40.7 19.9 1.7e-10 40.4 19.9 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167196.1_37922001_1 - 4.6e-91 305.0 25.6 5.5e-91 304.7 25.6 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167196.1_37922001_1 - 5.4e-06 25.6 25.2 7.9e-06 25.1 25.2 1.2 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167236.1_37922001_1 - 5.3e-87 291.7 23.1 5.3e-87 291.7 23.1 1.8 2 0 0 2 2 2 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167236.1_37922001_1 - 9e-05 21.7 18.3 0.0001 21.5 17.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001167290.1_37922001_1 - 2.6e-85 286.1 15.6 3.4e-85 285.7 15.6 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R BatA PF07584.9 001167290.1_37922001_1 - 0.029 14.6 2.9 4.6 7.6 0.4 2.7 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal V1R PF03402.12 001167274.1_37922001_1 - 1.8e-92 309.6 20.9 1.8e-92 309.6 20.9 1.5 2 0 0 2 2 2 1 Vomeronasal organ pheromone receptor family, V1R BatA PF07584.9 001167274.1_37922001_1 - 0.0056 16.9 2.9 0.95 9.8 0.1 2.8 2 0 0 2 2 2 2 Aerotolerance regulator N-terminal 7tm_1 PF00001.19 001167274.1_37922001_1 - 0.029 13.5 15.8 0.038 13.1 15.1 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001167230.1_37922001_1 - 1.1e-87 293.8 19.2 1.5e-87 293.4 19.2 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R BatA PF07584.9 001167230.1_37922001_1 - 0.017 15.4 1.5 4.6 7.6 0.0 2.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF4079 PF13301.4 001167230.1_37922001_1 - 0.04 13.9 11.7 0.17 11.9 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) V1R PF03402.12 001167235.1_37922001_1 - 9.5e-88 294.1 15.2 1.3e-87 293.7 15.2 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R V1R PF03402.12 001167238.1_37922001_1 - 9.7e-90 300.6 27.3 1.2e-89 300.3 27.3 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167238.1_37922001_1 - 1.1e-07 31.1 24.0 1.6e-07 30.6 24.0 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) UPF0182 PF03699.11 001167238.1_37922001_1 - 0.063 11.3 9.7 0.084 10.9 9.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) V1R PF03402.12 001167213.1_37922001_1 - 1.6e-69 234.4 16.6 2.1e-69 234.0 16.6 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167213.1_37922001_1 - 2.8e-05 23.2 17.3 3.7e-05 22.8 17.3 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167221.1_37922001_1 - 8.6e-105 350.0 24.3 1e-104 349.7 24.3 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167221.1_37922001_1 - 0.008 15.3 19.1 0.011 14.8 19.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2157 PF09925.7 001167221.1_37922001_1 - 4.2 7.0 8.7 1.6 8.4 1.8 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) V1R PF03402.12 001167229.1_37922001_1 - 1.5e-95 319.7 23.5 1.8e-95 319.5 23.5 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167229.1_37922001_1 - 2.3e-06 26.8 24.2 3.5e-06 26.2 24.2 1.2 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167302.1_37922001_1 - 1e-27 97.3 16.5 1.4e-27 96.9 16.5 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167302.1_37922001_1 - 1.7e-08 33.8 23.4 2e-08 33.6 23.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167270.1_37922001_1 - 1.2e-28 100.3 16.3 1.6e-28 99.9 16.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167270.1_37922001_1 - 3.6e-08 32.7 22.7 4.4e-08 32.5 22.7 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001167201.1_37922001_1 - 2.7e-56 191.0 24.9 3.2e-56 190.7 24.9 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167201.1_37922001_1 - 3.6e-05 22.9 28.4 4.9e-05 22.5 28.4 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF4131 PF13567.4 001167201.1_37922001_1 - 1.3 8.4 3.8 9 5.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) V1R PF03402.12 001167231.1_37922001_1 - 2.8e-92 309.0 15.3 3.7e-92 308.5 15.3 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R BatA PF07584.9 001167231.1_37922001_1 - 0.15 12.3 2.3 5.5 7.3 0.7 2.8 2 1 0 2 2 2 0 Aerotolerance regulator N-terminal V1R PF03402.12 001167227.1_37922001_1 - 1.9e-94 316.1 17.8 2.6e-94 315.6 17.8 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001167227.1_37922001_1 - 0.011 14.8 13.8 0.013 14.7 12.8 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) BatA PF07584.9 001167227.1_37922001_1 - 0.083 13.1 2.1 9.2 6.6 0.0 2.7 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal V1R PF03402.12 001167280.1_37922001_1 - 8.8e-95 317.2 24.9 1e-94 316.9 24.9 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167280.1_37922001_1 - 4e-09 35.9 22.5 5.4e-09 35.5 22.5 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF986 PF06173.10 001167280.1_37922001_1 - 2 8.2 7.9 0.69 9.7 0.1 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF986) V1R PF03402.12 001167240.1_37922001_1 - 1.6e-88 296.7 19.0 2.3e-88 296.1 19.0 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R LRR_8 PF13855.4 001297479.1_37926001_1 - 7.8e-35 118.3 62.6 5.6e-15 54.7 6.4 8.8 10 1 1 11 11 11 6 Leucine rich repeat LRR_4 PF12799.5 001297479.1_37926001_1 - 1.5e-14 53.6 56.5 3.4e-07 30.3 3.0 10.5 5 3 4 11 11 11 6 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001297479.1_37926001_1 - 6.2e-11 42.4 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001297479.1_37926001_1 - 1.9e-08 34.2 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001297479.1_37926001_1 - 4.6e-06 26.1 3.5 0.0087 15.4 0.1 3.3 2 1 1 3 3 3 2 Leucine-rich repeat LRR_5 PF13306.4 001297479.1_37926001_1 - 2.2e-05 24.3 0.0 0.13 12.1 0.0 3.6 3 1 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_6 PF13516.4 001297479.1_37926001_1 - 0.00012 21.7 31.4 0.32 11.0 0.0 9.7 10 0 0 10 10 10 4 Leucine Rich repeat DUF3329 PF11808.6 001297479.1_37926001_1 - 0.0024 18.1 0.6 0.0024 18.1 0.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3329) LRR_1 PF00560.31 001297479.1_37926001_1 - 0.61 10.6 53.5 0.36 11.3 0.7 11.8 12 2 0 12 12 12 0 Leucine Rich Repeat p450 PF00067.20 001284028.1_29524001_2 - 4.5e-150 500.3 3.0 5.1e-150 500.1 3.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pribosyltran_N PF13793.4 001284723.1_29524001_1 - 6.3e-47 158.2 0.5 1.5e-46 156.9 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.4 001284723.1_29524001_1 - 5.2e-43 147.1 2.6 1.8e-36 125.8 1.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.25 001284723.1_29524001_1 - 1.9e-13 50.1 0.3 6.8e-13 48.3 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.4 001284723.1_29524001_1 - 0.001 18.4 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pou PF00157.15 001285590.1_09023001_3 - 2.9e-38 129.6 1.1 7.3e-38 128.3 1.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001285590.1_09023001_3 - 1.2e-18 66.5 0.5 2.4e-18 65.5 0.5 1.5 1 0 0 1 1 1 1 Homeobox domain DUF521 PF04412.11 001285590.1_09023001_3 - 0.029 12.9 0.4 0.074 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF521) LRR_8 PF13855.4 001285543.1_09027001_1 - 2.2e-55 184.2 101.1 2e-09 36.9 7.2 14.4 9 4 3 13 13 13 12 Leucine rich repeat LRR_4 PF12799.5 001285543.1_09027001_1 - 5e-30 102.8 97.8 1.2e-07 31.7 3.5 15.5 10 5 7 18 18 18 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001285543.1_09027001_1 - 6.7e-10 37.9 69.2 2 9.1 0.6 18.9 17 3 1 18 18 18 6 Leucine Rich Repeat LRR_5 PF13306.4 001285543.1_09027001_1 - 4.1e-09 36.3 25.1 0.0016 18.3 1.7 6.9 5 2 0 7 7 7 4 Leucine rich repeats (6 copies) TIR PF01582.18 001285543.1_09027001_1 - 2.8e-06 27.1 0.0 4.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001285543.1_09027001_1 - 9.2e-05 21.9 41.6 0.025 14.0 1.3 6.7 3 3 5 8 8 8 5 Leucine-rich repeat LRR_6 PF13516.4 001285543.1_09027001_1 - 0.00013 21.7 57.6 1.3 9.1 0.2 15.4 16 0 0 16 16 16 3 Leucine Rich repeat CENP-L PF13092.4 001285543.1_09027001_1 - 0.052 13.6 0.1 7.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 Homeobox PF00046.27 001285601.1_09022001_1 - 2.6e-21 75.0 4.9 3.9e-21 74.5 4.9 1.3 1 0 0 1 1 1 1 Homeobox domain Asp PF00026.21 001285564.1_09023001_1 - 1.7e-97 326.5 0.0 2.1e-97 326.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285564.1_09023001_1 - 4.6e-14 53.0 0.9 2.1e-07 31.3 0.0 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001285564.1_09023001_1 - 3.7e-10 39.3 1.2 3.7e-10 39.3 1.2 1.9 2 0 0 2 2 2 1 A1 Propeptide Asp_protease_2 PF13650.4 001285564.1_09023001_1 - 0.00028 21.4 0.1 0.021 15.4 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease Asp PF00026.21 001285562.1_09023001_1 - 3.6e-94 315.6 0.0 4.5e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease A1_Propeptide PF07966.10 001285562.1_09023001_1 - 7.8e-14 51.1 0.8 1.3e-13 50.3 0.8 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_N PF14543.4 001285562.1_09023001_1 - 3.9e-10 40.1 0.2 4.6e-08 33.4 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal PMG PF05287.10 001285770.1_09022001_1 - 3.8e-50 170.3 44.3 4.9e-50 169.9 44.3 1.1 1 0 0 1 1 1 1 PMG protein LRR_4 PF12799.5 001285583.1_09023001_1 - 2.5e-06 27.6 3.0 0.36 11.2 0.0 4.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.4 001285583.1_09023001_1 - 3.3e-05 23.4 10.7 0.0036 17.1 0.1 5.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.4 001285583.1_09023001_1 - 0.00011 21.7 1.7 2.4 7.8 0.1 4.3 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.31 001285583.1_09023001_1 - 0.012 15.8 8.1 14 6.5 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat Keratin_matx PF04579.10 001285773.1_09022001_3 - 4.5e-40 135.8 35.2 1.2e-39 134.4 35.2 1.6 1 1 0 1 1 1 1 Keratin, high-sulphur matrix protein LRR_8 PF13855.4 001285541.1_09025001_1 - 1.2e-17 63.2 36.1 3.4e-10 39.4 2.2 6.6 4 3 3 7 7 7 5 Leucine rich repeat LRR_4 PF12799.5 001285541.1_09025001_1 - 6e-15 54.9 32.3 1.5e-05 25.1 0.1 7.4 3 3 5 8 8 8 8 Leucine Rich repeats (2 copies) TIR PF01582.18 001285541.1_09025001_1 - 1.6e-12 47.4 0.0 2.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001285541.1_09025001_1 - 0.00025 20.5 10.2 0.16 11.3 0.2 3.3 3 0 0 3 3 3 2 Leucine-rich repeat TIR_2 PF13676.4 001285541.1_09025001_1 - 0.00055 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain Adeno_E3 PF06040.9 001285541.1_09025001_1 - 0.044 13.8 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Adenovirus E3 protein LRR_6 PF13516.4 001285541.1_09025001_1 - 0.23 11.5 32.1 12 6.1 0.1 10.0 12 0 0 12 12 12 0 Leucine Rich repeat Asp PF00026.21 001285621.1_09023001_1 - 1e-82 278.0 0.0 8.8e-50 169.8 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease A1_Propeptide PF07966.10 001285621.1_09023001_1 - 5.1e-15 54.8 1.7 8.1e-15 54.2 1.7 1.3 1 0 0 1 1 1 1 A1 Propeptide TAXi_N PF14543.4 001285621.1_09023001_1 - 1.3e-11 44.9 0.0 1.4e-07 31.8 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.4 001285621.1_09023001_1 - 7.3e-05 23.3 0.0 0.01 16.4 0.0 3.2 2 1 1 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.4 001285621.1_09023001_1 - 0.019 15.4 0.0 1.4 9.4 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.21 001285558.1_09023001_1 - 8.7e-104 347.2 0.1 1e-103 347.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285558.1_09023001_1 - 3.1e-15 56.8 0.4 3.1e-08 34.0 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001285558.1_09023001_1 - 7.3e-09 35.2 0.1 1.2e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.4 001285558.1_09023001_1 - 3.2e-05 24.4 0.0 0.077 13.6 0.1 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.4 001285558.1_09023001_1 - 0.0095 16.3 0.0 6.1 7.3 0.0 3.1 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp PF00026.21 001285556.1_09023001_1 - 5.7e-99 331.4 0.0 7.2e-99 331.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease A1_Propeptide PF07966.10 001285556.1_09023001_1 - 2.7e-15 55.8 2.2 1.9e-14 53.0 1.0 2.3 2 0 0 2 2 2 1 A1 Propeptide TAXi_N PF14543.4 001285556.1_09023001_1 - 1.8e-14 54.3 0.1 2.1e-12 47.5 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.4 001285556.1_09023001_1 - 2.7e-06 27.8 0.0 0.02 15.5 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.4 001285556.1_09023001_1 - 0.0036 17.7 0.0 1.7 9.1 0.0 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp PF00026.21 001285552.1_09023001_1 - 5e-99 331.5 0.0 6.2e-99 331.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285552.1_09023001_1 - 8.5e-16 58.6 0.4 3.2e-14 53.5 0.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001285552.1_09023001_1 - 1e-13 50.7 1.0 2.4e-13 49.5 1.0 1.7 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.4 001285552.1_09023001_1 - 0.001 19.6 0.0 0.099 13.2 0.0 3.3 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.4 001285552.1_09023001_1 - 0.16 12.4 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease 7tm_1 PF00001.19 001126370.2_39524001_1 - 5.4e-31 107.7 38.1 2.7e-30 105.4 38.1 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001126370.2_39524001_1 - 2.9e-10 40.2 23.5 1.2e-09 38.2 15.2 2.4 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.7 001126370.2_39524001_1 - 5.3e-10 39.0 30.5 9.1e-10 38.2 30.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx MHC_I PF00129.16 002155.1_45722120_1 - 5.7e-35 120.4 0.2 7.3e-35 120.0 0.2 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I PF00129.16 002155.1_45722120_2 - 2.8e-41 140.9 0.8 3.7e-41 140.5 0.8 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Epiglycanin_TR PF05647.9 002316.2_45727120_3 - 4.3 7.2 25.9 7.6 6.4 25.9 1.3 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like V1R PF03402.12 001253593.2_37622001_1 - 3.3e-38 131.7 11.3 4.6e-38 131.2 11.3 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001253593.2_37622001_1 - 8.3e-12 44.7 14.6 1e-11 44.4 14.6 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001253593.2_37622001_1 - 0.00024 20.3 10.7 0.00035 19.7 10.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V1R PF03402.12 001167413.1_09923001_1 - 4.5e-34 118.1 14.2 7.1e-34 117.5 14.2 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167413.1_09923001_1 - 6.4e-10 38.5 15.4 8.3e-10 38.1 15.4 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_1 PF00001.19 001167413.1_09923001_1 - 0.00014 21.0 13.4 0.00022 20.4 13.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.19 001286590.1_49825001_1 - 9.2e-25 87.3 5.0 9.2e-25 87.3 5.0 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001286590.1_49825001_1 - 0.00011 21.6 2.8 0.00024 20.4 2.8 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.19 001286590.1_49825001_2 - 3.5e-24 85.3 0.4 5.1e-24 84.8 0.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_P21 PF05313.10 001286590.1_49825001_2 - 0.0085 15.6 0.6 0.047 13.1 0.7 1.9 2 0 0 2 2 2 1 Poxvirus P21 membrane protein DUF1385 PF07136.9 001286590.1_49825001_2 - 0.0095 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) Ion_trans PF00520.29 001166572.1_06529001_3 - 6.8e-35 120.3 17.1 6.8e-35 120.3 17.1 2.0 2 0 0 2 2 2 1 Ion transport protein TRP_2 PF08344.9 001166572.1_06529001_3 - 1.7e-26 92.1 1.0 3.9e-26 90.9 1.0 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.10 001166572.1_06529001_3 - 6.3e-14 51.3 14.4 1.2e-13 50.4 14.4 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.5 001166572.1_06529001_3 - 1.3e-10 41.6 0.4 4.7e-07 30.2 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001166572.1_06529001_3 - 0.00014 22.0 1.1 0.092 13.0 0.2 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.4 001166572.1_06529001_3 - 0.00016 22.0 0.5 0.003 18.0 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.4 001166572.1_06529001_3 - 0.0023 18.2 2.7 14 6.5 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat ING PF12998.5 001166572.1_06529001_3 - 0.048 14.1 3.8 0.34 11.4 1.5 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Ank PF00023.28 001166572.1_06529001_3 - 0.052 13.9 1.4 20 5.7 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat XkdW PF09636.8 001166572.1_06529001_3 - 0.093 12.7 0.5 0.27 11.2 0.5 1.9 1 0 0 1 1 1 0 XkdW protein zf-RING_UBOX PF13445.4 001206574.1_06529001_1 - 1.4e-08 34.4 6.5 1.4e-08 34.4 6.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.22 001206574.1_06529001_1 - 3.7e-08 33.3 26.1 6.5e-07 29.3 4.9 3.7 3 0 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.23 001206574.1_06529001_1 - 5.4e-07 29.3 8.4 5.4e-07 29.3 8.4 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001206574.1_06529001_1 - 1e-06 28.3 9.0 1e-06 28.3 9.0 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001206574.1_06529001_1 - 1.3e-06 28.0 6.9 1.3e-06 28.0 6.9 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001206574.1_06529001_1 - 1.4e-05 24.8 7.1 1.4e-05 24.8 7.1 3.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.4 001206574.1_06529001_1 - 1.6e-05 24.9 8.0 1.6e-05 24.9 8.0 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.4 001206574.1_06529001_1 - 7e-05 22.8 8.7 7e-05 22.8 8.7 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.3 001206574.1_06529001_1 - 1.7 8.3 4.1 1.1 8.9 1.4 2.2 1 1 1 2 2 2 0 RING-like zinc finger KRAB PF01352.25 001106792.1_45729001_3 - 6.8e-15 54.3 0.1 1.2e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 KRAB box zf-H2C2_2 PF13465.4 001106792.1_45729001_3 - 6.8e-15 54.6 48.4 9.2e-06 25.8 1.7 7.5 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.4 001106792.1_45729001_3 - 1.4e-10 41.0 51.5 0.041 14.6 4.4 7.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.24 001106792.1_45729001_3 - 1.2e-07 31.7 82.6 0.001 19.3 4.9 7.1 7 1 0 7 7 7 5 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.8 001106792.1_45729001_3 - 0.082 12.9 16.5 0.97 9.5 4.3 3.7 3 0 0 3 3 3 0 Zinc ribbon domain FYDLN_acid PF09538.8 001106792.1_45729001_3 - 0.27 11.8 8.7 5.3 7.6 0.3 3.9 2 2 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_9 PF14369.4 001106792.1_45729001_3 - 0.75 10.0 0.0 0.75 10.0 0.0 4.4 5 0 0 5 5 5 0 zinc-ribbon DUF3268 PF11672.6 001106792.1_45729001_3 - 2.3 8.5 7.4 0.87 9.8 0.7 2.6 2 1 0 2 2 2 0 zinc-finger-containing domain zf-C2H2_9 PF16293.3 001106792.1_45729001_3 - 3.9 7.2 6.7 32 4.3 0.9 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) PLA2_inh PF02988.13 001109633.1_45722001_2 - 0.67 10.5 18.6 0.69 10.5 0.5 2.8 3 1 0 3 3 3 0 Phospholipase A2 inhibitor WD40 PF00400.30 037919.1_45722120_1 - 5.9e-16 58.4 9.2 1.4e-07 31.9 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Capsid_NCLDV PF04451.10 037919.1_45722120_1 - 0.068 12.8 0.1 0.13 11.9 0.0 1.4 2 0 0 2 2 2 0 Large eukaryotic DNA virus major capsid protein WD40 PF00400.30 037919.1_45722120_2 - 0.0086 16.8 0.1 0.021 15.6 0.1 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat BTB PF00651.29 213564.3_45726001_1 - 3.5e-21 75.4 0.0 5.3e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.24 213564.3_45726001_1 - 0.00059 20.0 20.7 0.005 17.1 4.9 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 213564.3_45726001_1 - 0.02 15.5 2.8 0.02 15.5 2.8 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 213564.3_45726001_1 - 0.32 11.0 3.5 0.14 12.2 0.4 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.4 213564.3_45726001_1 - 0.58 10.0 10.3 3.5 7.5 2.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 213564.3_45726001_1 - 0.97 9.7 4.8 2.3 8.5 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LLC1 PF14945.4 001109573.1_45722001_3 - 1.2e-06 29.0 1.5 3.4e-06 27.5 0.5 2.0 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein FAM217 PF15344.4 001134551.1_45723001_3 - 7e-86 287.9 0.2 7e-86 287.9 0.2 1.7 2 0 0 2 2 2 1 FAM217 family DLEU7 PF15760.3 001106043.1_45724001_2 - 1.2e-34 119.4 1.1 1.2e-34 119.4 1.1 2.1 2 0 0 2 2 2 1 Leukemia-associated protein 7 DLEU7 PF15760.3 001106043.1_45724001_3 - 1.5e-76 256.1 0.1 2.6e-76 255.3 0.1 1.4 1 0 0 1 1 1 1 Leukemia-associated protein 7 Yae1_N PF09811.7 001107565.1_45726001_2 - 8.8e-11 41.2 7.4 1.4e-10 40.5 7.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ODC_AZ PF02100.15 001290366.1_24222001_2 - 6.9e-14 51.7 0.0 9.9e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ODC_AZ PF02100.15 001290529.1_09022001_1 - 5.1e-15 55.4 0.0 6.9e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme CSD PF00313.20 073158.1_45726120_3 - 4.6e-11 42.3 0.0 7.9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.21 073158.1_45726120_3 - 0.00016 21.5 9.0 0.00026 20.8 3.0 2.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.4 073158.1_45726120_3 - 2.4 7.8 9.0 2.4 7.8 1.6 2.7 2 0 0 2 2 2 0 Zinc knuckle 7tm_4 PF13853.4 001001269.1_45722001_1 - 4.3e-130 433.3 26.3 5.2e-130 433.0 26.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001269.1_45722001_1 - 7.7e-21 74.4 19.6 1.3e-20 73.6 19.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001269.1_45722001_1 - 5.5e-07 29.1 16.5 9e-07 28.4 16.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000484.1_45722001_1 - 2.3e-47 161.9 14.1 2.8e-47 161.7 14.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000484.1_45722001_1 - 3.9e-22 78.6 16.3 6.7e-22 77.9 16.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000484.1_45722001_1 - 0.0001 21.6 16.0 0.00016 21.0 16.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cyclin_N PF00134.21 001000484.1_45722001_1 - 0.065 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain 7tm_4 PF13853.4 001000056.1_45722001_1 - 3.1e-42 145.1 19.0 4e-42 144.7 19.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000056.1_45722001_1 - 2.3e-24 85.9 24.7 5.7e-24 84.7 24.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000991.1_45722001_1 - 2.7e-40 138.7 22.5 3.3e-40 138.5 22.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000991.1_45722001_1 - 1.8e-15 56.8 23.9 4.2e-15 55.6 23.9 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000490.1_45722001_1 - 6.7e-51 173.5 19.2 8.2e-51 173.2 19.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000490.1_45722001_1 - 2.5e-18 66.2 23.4 6.1e-18 64.9 23.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SLC3A2_N PF16028.3 001000490.1_45722001_1 - 0.13 11.7 0.2 0.13 11.7 0.2 2.4 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.4 001001287.1_45722001_1 - 8.7e-105 350.3 26.3 9.8e-105 350.1 26.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001287.1_45722001_1 - 2.5e-21 76.0 23.6 4e-21 75.3 23.6 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001287.1_45722001_1 - 0.0007 18.9 22.5 0.0013 18.1 22.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000491.1_45722001_1 - 3.7e-52 177.7 22.5 4.4e-52 177.4 22.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000491.1_45722001_1 - 6.4e-17 61.5 24.7 1.8e-16 60.1 24.7 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000283.1_45722001_1 - 3.4e-49 167.9 22.3 4.3e-49 167.6 22.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000283.1_45722001_1 - 7.1e-20 71.2 25.6 3.2e-19 69.1 25.6 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000283.1_45722001_1 - 2.8e-06 26.8 26.9 9.4e-06 25.1 26.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2254 PF10011.7 001000283.1_45722001_1 - 0.018 13.7 3.5 0.11 11.2 0.1 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2254) 7TM_GPCR_Srx PF10328.7 001000283.1_45722001_1 - 0.15 11.2 29.2 0.21 10.7 29.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF2842 PF11003.6 001000283.1_45722001_1 - 1.4 9.1 10.3 2.5 8.3 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2842) 7tm_4 PF13853.4 001001026.1_45722001_1 - 8.6e-100 333.9 25.1 1.1e-99 333.6 25.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001026.1_45722001_1 - 3.7e-15 55.7 22.1 1.4e-14 53.9 22.1 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001026.1_45722001_1 - 8.6e-06 25.2 21.8 1.5e-05 24.4 21.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001001026.1_45722001_1 - 0.0026 17.0 21.2 0.0072 15.5 21.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001001048.1_45722001_1 - 5.8e-48 163.9 22.5 7e-48 163.6 22.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001048.1_45722001_1 - 3.6e-21 75.4 23.5 7.2e-21 74.5 23.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000560.1_45722001_1 - 9.5e-56 189.4 24.5 1.2e-55 189.1 24.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000560.1_45722001_1 - 5.1e-25 88.1 28.3 5.2e-24 84.8 28.3 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000654.1_45722001_1 - 1.9e-45 155.6 17.3 2.4e-45 155.3 17.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000654.1_45722001_1 - 1.2e-15 57.3 19.0 2.9e-15 56.1 19.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000102.1_45723001_1 - 6.7e-48 163.7 20.6 8.6e-48 163.3 20.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000102.1_45723001_1 - 4.4e-23 81.7 19.6 4.4e-23 81.7 19.6 1.7 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000102.1_45723001_1 - 5.6e-07 29.1 22.2 1e-06 28.2 22.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2842 PF11003.6 001000102.1_45723001_1 - 0.47 10.6 0.1 0.47 10.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2842) DUF2615 PF11027.6 001000102.1_45723001_1 - 0.53 10.3 2.3 6.8 6.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) 7tm_4 PF13853.4 001000873.1_45722001_1 - 1.1e-53 182.7 24.0 1.3e-53 182.4 24.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000873.1_45722001_1 - 7.1e-25 87.6 20.3 1.2e-24 86.9 20.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000873.1_45722001_1 - 0.00015 21.1 17.8 0.00016 21.0 16.4 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 214831.1_45722001_1 - 2.8e-58 197.7 17.9 3.3e-58 197.5 17.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 214831.1_45722001_1 - 6.5e-24 84.5 28.2 6.2e-23 81.3 28.2 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001001080.1_45722001_1 - 2.8e-49 168.2 32.1 3.3e-49 168.0 32.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001080.1_45722001_1 - 3.9e-23 81.9 29.5 7.8e-23 80.9 29.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001080.1_45722001_1 - 6.3e-05 22.3 36.5 0.00084 18.7 36.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001001103.1_45722001_1 - 3.3e-49 168.0 18.7 3.8e-49 167.8 18.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001103.1_45722001_1 - 1e-19 70.7 19.8 2.3e-19 69.6 19.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001103.1_45722001_1 - 1.1e-06 28.1 20.1 4.2e-06 26.2 20.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000238.1_45722001_1 - 1.9e-47 162.2 16.7 2.4e-47 161.8 16.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000238.1_45722001_1 - 3.6e-20 72.2 20.4 6.1e-20 71.4 20.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000238.1_45722001_1 - 4.4e-05 22.9 9.0 4.4e-05 22.9 9.0 1.9 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000266.1_45722001_1 - 1.1e-47 163.0 16.2 1.4e-47 162.6 16.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000266.1_45722001_1 - 2e-26 92.7 20.7 3.7e-26 91.8 20.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3377 PF11857.6 001000266.1_45722001_1 - 0.07 12.9 0.5 0.07 12.9 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) 7tm_4 PF13853.4 001000353.1_45722001_1 - 2.3e-48 165.2 21.4 3e-48 164.8 21.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000353.1_45722001_1 - 1.7e-16 60.1 23.3 5.7e-16 58.4 23.2 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SLC3A2_N PF16028.3 001000353.1_45722001_1 - 7.6 6.0 9.3 13 5.3 0.2 3.0 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.4 001001272.1_45722001_1 - 1.2e-112 376.1 26.1 1.3e-112 375.9 26.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001272.1_45722001_1 - 7.3e-21 74.5 23.7 4e-20 72.0 23.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001272.1_45722001_1 - 9.1e-06 25.1 17.4 6.8e-05 22.2 17.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000877.1_45722001_1 - 5.7e-52 177.0 25.7 7.1e-52 176.7 25.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000877.1_45722001_1 - 9.5e-23 80.6 29.6 2.6e-22 79.2 29.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000877.1_45722001_1 - 2.1e-07 30.4 31.4 3.3e-06 26.5 31.4 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000274.1_45722001_1 - 3.1e-44 151.7 11.5 4e-44 151.3 11.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000274.1_45722001_1 - 1.2e-21 77.1 18.4 2.4e-21 76.0 18.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000274.1_45722001_1 - 3e-05 23.4 13.7 5e-05 22.7 13.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000739.1_45722001_1 - 5.3e-111 370.7 22.1 5.9e-111 370.5 22.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000739.1_45722001_1 - 1e-20 74.0 25.5 2.8e-20 72.5 25.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000739.1_45722001_1 - 7.3e-07 28.7 20.3 1.2e-06 28.0 20.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Suc_Fer-like PF06999.10 001000739.1_45722001_3 - 0.18 11.5 3.6 0.23 11.2 3.6 1.2 1 0 0 1 1 1 0 Sucrase/ferredoxin-like 7tm_4 PF13853.4 001000473.1_45722001_1 - 3.1e-51 174.6 25.0 3.7e-51 174.4 25.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000473.1_45722001_1 - 2.4e-21 76.0 25.4 4.2e-21 75.2 25.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000473.1_45722001_1 - 0.013 14.8 25.5 0.014 14.6 24.6 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000260.1_45722001_1 - 3.1e-58 197.6 19.9 3.7e-58 197.3 19.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000260.1_45722001_1 - 9.6e-24 83.9 25.1 2.6e-23 82.5 25.1 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000260.1_45722001_1 - 1.1e-08 34.7 22.4 3.5e-08 33.0 22.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CCDC92 PF14916.4 001000260.1_45722001_3 - 0.067 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function 7tm_4 PF13853.4 001001009.1_45722001_1 - 2.2e-49 168.6 22.5 2.7e-49 168.3 22.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001009.1_45722001_1 - 2.5e-17 62.9 21.9 7.4e-17 61.3 21.9 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001009.1_45722001_1 - 1.3e-06 27.9 24.0 4e-06 26.3 23.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000905.1_45722001_1 - 2.4e-42 145.5 19.4 3.1e-42 145.1 19.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000905.1_45722001_1 - 1.1e-16 60.7 22.2 2.7e-16 59.5 22.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000905.1_45722001_1 - 0.00022 20.6 27.1 0.00038 19.8 26.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000905.1_45722001_1 - 0.38 9.9 24.6 0.34 10.0 23.6 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001000078.1_45722001_1 - 4.4e-54 184.0 22.3 5.2e-54 183.7 22.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000078.1_45722001_1 - 9.8e-18 64.2 23.5 1.9e-17 63.2 23.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SLC3A2_N PF16028.3 001000078.1_45722001_1 - 6.1 6.3 5.9 0.98 8.9 0.7 2.4 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.4 001000210.1_45722001_1 - 2.8e-50 171.5 16.2 3.4e-50 171.2 16.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000210.1_45722001_1 - 7.4e-21 74.4 18.3 1.3e-20 73.6 18.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000794.1_45722001_1 - 1.3e-48 166.1 10.1 1.5e-48 165.8 10.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000794.1_45722001_1 - 1.7e-21 76.6 14.0 3e-21 75.7 14.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000794.1_45722001_1 - 0.00016 21.0 13.6 0.00018 20.9 12.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000794.1_45722001_1 - 0.0023 17.2 9.4 0.0023 17.2 9.4 2.3 1 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4133 PF13571.4 001000794.1_45722001_1 - 4.7 7.5 7.7 4.1 7.7 1.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4133) 7tm_3 PF00003.20 001099512.1_45726001_1 - 1.3e-54 185.4 33.4 1.3e-54 185.4 33.4 2.1 3 0 0 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099512.1_45726001_1 - 8.8e-31 107.1 0.5 1.3e-30 106.6 0.5 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099512.1_45726001_1 - 3.4e-18 65.2 11.0 8.2e-18 64.0 11.0 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR 7tm_4 PF13853.4 001000761.1_45722001_1 - 8.5e-54 183.0 20.9 1.1e-53 182.7 20.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000761.1_45722001_1 - 6.4e-17 61.5 24.2 1.3e-16 60.5 24.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000426.1_45722001_1 - 6.6e-51 173.5 28.0 8.5e-51 173.2 28.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000426.1_45722001_1 - 1.6e-21 76.6 28.1 3.3e-21 75.6 28.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000426.1_45722001_1 - 0.042 13.1 30.6 0.088 12.0 30.6 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000776.1_45722001_1 - 1.3e-38 133.3 18.4 1.5e-38 133.0 18.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000776.1_45722001_1 - 1.3e-22 80.2 18.7 1.5e-21 76.7 18.7 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000776.1_45722001_1 - 0.02 14.1 18.5 0.049 12.9 18.5 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001001122.1_45722001_1 - 7.9e-46 156.9 16.2 1e-45 156.5 16.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001122.1_45722001_1 - 7.1e-18 64.7 21.3 2e-17 63.2 21.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PKD_channel PF08016.10 001001122.1_45722001_1 - 1.9 6.9 16.3 0.013 14.0 4.6 2.3 1 1 1 2 2 2 0 Polycystin cation channel 7tm_4 PF13853.4 001000838.1_45722001_1 - 2e-52 178.5 23.0 2.5e-52 178.2 23.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000838.1_45722001_1 - 3.2e-23 82.2 29.4 2.5e-22 79.2 29.4 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000838.1_45722001_1 - 0.00097 18.5 28.4 0.0023 17.2 28.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000482.1_45722001_1 - 2e-53 181.8 20.6 2.5e-53 181.5 20.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000482.1_45722001_1 - 2.9e-21 75.8 23.6 5.9e-21 74.8 23.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_I5 PF04713.10 001000482.1_45722001_1 - 5.3 7.0 12.9 0.65 10.0 1.8 3.4 3 0 0 3 3 3 0 Poxvirus protein I5 7tm_4 PF13853.4 001000209.1_45722001_1 - 2e-51 175.3 19.2 2.4e-51 175.0 19.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000209.1_45722001_1 - 5.6e-24 84.7 21.9 1.4e-23 83.4 21.9 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000209.1_45722001_1 - 4.5e-07 29.4 20.0 1e-06 28.2 20.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GRDA PF04723.12 001000209.1_45722001_1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A 7tm_4 PF13853.4 001000589.1_45722001_1 - 1.4e-50 172.5 22.4 1.7e-50 172.2 22.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000589.1_45722001_1 - 1e-21 77.3 25.0 2.3e-21 76.1 25.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DAN PF03045.13 001000589.1_45722001_1 - 0.13 12.1 1.0 8.7 6.2 0.0 2.9 3 0 0 3 3 3 0 DAN domain DUF3810 PF12725.5 001000589.1_45722001_1 - 1.4 8.0 16.0 0.13 11.4 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Gemini_mov PF01708.14 001000589.1_45722001_1 - 3 7.5 7.0 0.12 12.0 0.8 1.8 2 0 0 2 2 2 0 Geminivirus putative movement protein Tetraspannin PF00335.18 001000589.1_45722001_1 - 7.2 6.2 18.5 5.7 6.6 1.3 2.4 2 0 0 2 2 2 0 Tetraspanin family 7tm_4 PF13853.4 001000270.1_45722001_1 - 5.2e-45 154.2 10.7 6.3e-45 153.9 10.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000270.1_45722001_1 - 2.7e-23 82.4 13.5 5.2e-23 81.5 13.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000270.1_45722001_1 - 2.4e-05 23.7 12.7 4.6e-05 22.8 12.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.7 001000270.1_45722001_1 - 0.0012 18.2 4.6 0.0023 17.4 4.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srv PF10323.7 001000270.1_45722001_1 - 0.0015 17.8 11.9 0.0032 16.7 11.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001000406.1_45722001_1 - 7.2e-60 202.9 10.7 8.8e-60 202.7 10.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000406.1_45722001_1 - 2.7e-25 89.0 9.5 5.5e-25 88.0 9.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000406.1_45722001_1 - 0.00029 20.2 13.8 0.00058 19.2 13.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000881.1_45722001_1 - 2.5e-51 174.9 28.0 3e-51 174.7 28.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000881.1_45722001_1 - 3.4e-21 75.6 26.9 6.4e-21 74.6 26.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000881.1_45722001_1 - 3.8e-07 29.6 29.3 2.8e-06 26.8 29.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000881.1_45722001_1 - 0.3 10.2 26.0 0.66 9.1 26.0 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001001014.1_45722001_1 - 1.7e-54 185.3 24.0 2e-54 185.1 24.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001014.1_45722001_1 - 2.7e-25 89.0 27.2 1.6e-24 86.4 27.2 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001014.1_45722001_1 - 0.00033 20.0 21.3 0.0018 17.6 21.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001001014.1_45722001_1 - 0.065 12.4 19.3 0.19 10.9 19.3 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001001271.1_45722001_1 - 1.4e-109 366.0 27.1 1.6e-109 365.8 27.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001271.1_45722001_1 - 9.3e-17 61.0 24.1 3.2e-16 59.3 24.1 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001271.1_45722001_1 - 0.00028 20.2 18.7 0.00052 19.3 18.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000236.1_45722001_1 - 7.8e-49 166.7 20.0 1e-48 166.3 20.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000236.1_45722001_1 - 1.5e-25 89.9 20.8 2.5e-25 89.1 20.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000236.1_45722001_1 - 2.1e-06 27.2 19.5 5.2e-06 25.9 19.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000236.1_45722001_1 - 0.003 16.8 9.0 0.003 16.8 9.0 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001000684.1_45722001_1 - 3.6e-45 154.7 26.4 4.5e-45 154.4 26.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000684.1_45722001_1 - 1.3e-16 60.5 31.4 3.7e-16 59.0 31.4 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_3 PF00003.20 001099471.1_45726001_1 - 4.3e-61 206.5 25.5 4.3e-61 206.5 25.5 1.8 3 0 0 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099471.1_45726001_1 - 3.4e-33 115.1 0.0 6.7e-33 114.1 0.0 1.3 1 1 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099471.1_45726001_1 - 9.3e-18 63.8 11.4 9.3e-18 63.8 11.4 1.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.11 001099471.1_45726001_1 - 2.4 7.8 7.9 7.9 6.2 7.9 1.9 1 0 0 1 1 1 0 Putative ephrin-receptor like 7tm_4 PF13853.4 001000439.1_45722001_1 - 8.4e-47 160.1 24.1 1.2e-46 159.5 24.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000439.1_45722001_1 - 7.6e-20 71.1 26.6 1.7e-19 70.0 26.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000439.1_45722001_1 - 8.2e-05 22.0 25.0 0.00012 21.5 25.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000587.1_45722001_1 - 1.8e-45 155.7 23.8 2.5e-45 155.3 23.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000587.1_45722001_1 - 2.1e-21 76.2 30.0 6.6e-21 74.6 30.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000378.1_45722001_1 - 3.1e-40 138.5 23.0 3.9e-40 138.2 23.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000378.1_45722001_1 - 2.2e-21 76.2 22.5 6e-21 74.7 22.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000561.1_45722001_1 - 2.4e-56 191.4 21.6 2.8e-56 191.1 21.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000561.1_45722001_1 - 6.4e-25 87.8 23.8 9.5e-25 87.2 23.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001001061.1_45722001_1 - 7.5e-45 153.7 20.1 1e-44 153.3 20.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001061.1_45722001_1 - 4.1e-16 58.9 23.1 1.7e-15 56.9 23.1 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SLC3A2_N PF16028.3 001001061.1_45722001_1 - 1.1 8.7 8.7 3 7.3 0.2 2.9 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.4 001000581.1_45722001_1 - 2.9e-59 201.0 12.8 3.5e-59 200.7 12.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000581.1_45722001_1 - 2.6e-25 89.1 12.2 5.1e-25 88.1 12.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000081.1_45722001_1 - 8.3e-51 173.2 7.0 1e-50 172.9 7.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000081.1_45722001_1 - 3.9e-20 72.1 11.0 9.4e-20 70.8 11.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000081.1_45722001_1 - 2.9e-08 33.3 2.5 2.9e-08 33.3 2.5 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.7 001000081.1_45722001_1 - 0.00051 19.3 7.3 0.001 18.4 7.1 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.7 001000081.1_45722001_1 - 0.26 10.4 7.5 0.059 12.6 4.2 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001000475.1_45722001_1 - 1.8e-53 181.9 26.7 2.1e-53 181.7 26.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000475.1_45722001_1 - 1.1e-21 77.2 30.6 1.9e-21 76.4 30.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000475.1_45722001_1 - 2.4e-05 23.7 28.6 2.4e-05 23.7 28.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000243.1_45722001_1 - 1.4e-49 169.2 15.5 1.8e-49 168.9 15.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000243.1_45722001_1 - 3.3e-21 75.6 17.9 5.4e-21 74.9 17.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000243.1_45722001_1 - 7.6e-08 31.9 6.5 7.6e-08 31.9 6.5 1.9 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000864.1_45722001_1 - 6.4e-49 167.0 22.8 7.7e-49 166.8 22.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000864.1_45722001_1 - 2.1e-20 72.9 24.1 7.2e-20 71.2 24.1 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000864.1_45722001_1 - 3.4e-06 26.5 19.3 1.4e-05 24.5 18.9 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000682.1_45722001_1 - 1.1e-50 172.9 27.1 1.3e-50 172.6 27.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000682.1_45722001_1 - 2.4e-22 79.3 24.5 3.9e-22 78.6 24.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000682.1_45722001_1 - 0.0008 18.7 25.2 0.0055 16.0 25.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000275.1_45723001_1 - 1.1e-41 143.3 13.6 1.3e-41 143.0 13.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000275.1_45723001_1 - 1.7e-20 73.2 22.0 4.4e-20 71.9 22.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000943.1_45722001_1 - 2.2e-52 178.4 29.4 2.7e-52 178.1 29.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000943.1_45722001_1 - 3.4e-24 85.4 30.2 1.2e-23 83.6 30.2 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000943.1_45722001_1 - 0.00014 21.2 29.4 0.00019 20.8 29.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000943.1_45722001_1 - 1.1 8.4 30.0 4.2 6.5 30.0 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001000281.1_45722001_1 - 4.2e-50 170.9 21.7 5.4e-50 170.6 21.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000281.1_45722001_1 - 1.9e-21 76.4 22.0 3.2e-21 75.6 22.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000281.1_45722001_1 - 2.1e-05 23.9 24.5 4.6e-05 22.8 24.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000294.1_45722001_1 - 8.6e-57 192.8 20.9 1.1e-56 192.5 20.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000294.1_45722001_1 - 5.2e-25 88.1 27.2 1.3e-24 86.7 27.2 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000294.1_45722001_1 - 8.9e-05 21.9 24.8 0.00016 21.0 20.4 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000423.1_45722001_1 - 1.9e-55 188.4 14.2 2.3e-55 188.1 14.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000423.1_45722001_1 - 5.7e-22 78.1 10.3 5.7e-22 78.1 10.3 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000423.1_45722001_1 - 2e-05 24.0 9.8 3.9e-05 23.0 9.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000156.1_45722001_1 - 1.7e-101 339.5 25.6 2e-101 339.2 25.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000156.1_45722001_1 - 3.5e-15 55.8 20.6 9.6e-15 54.4 20.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000914.1_45722001_1 - 5.4e-58 196.8 22.2 6.2e-58 196.6 22.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000914.1_45722001_1 - 4.5e-20 71.9 29.7 1.8e-19 69.9 29.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ATP-synt_8 PF00895.18 001000914.1_45722001_1 - 0.24 11.8 0.1 0.24 11.8 0.1 3.7 3 1 1 4 4 4 0 ATP synthase protein 8 HobA PF12163.6 001000914.1_45722001_3 - 0.013 15.0 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 DNA replication regulator 7tm_4 PF13853.4 001000299.1_45722001_1 - 6e-57 193.4 21.5 7e-57 193.1 21.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000299.1_45722001_1 - 3.1e-24 85.5 20.7 5.1e-24 84.8 20.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000596.1_45722001_1 - 1.5e-50 172.4 25.2 1.8e-50 172.1 25.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000596.1_45722001_1 - 5.9e-20 71.5 30.0 1.4e-19 70.2 30.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000297.1_45722001_1 - 7.1e-53 180.0 20.5 8.3e-53 179.8 20.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000297.1_45722001_1 - 1.1e-24 86.9 19.6 2.1e-24 86.0 19.6 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000297.1_45722001_1 - 3.6e-05 23.2 23.2 6.6e-05 22.3 23.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2254 PF10011.7 001000297.1_45722001_1 - 1.9 7.1 7.3 0.25 10.0 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) 7tm_4 PF13853.4 001000660.1_45722001_1 - 7.8e-45 153.6 20.2 9.2e-45 153.4 20.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000660.1_45722001_1 - 4.3e-16 58.8 22.5 1.3e-15 57.2 22.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000660.1_45722001_1 - 0.18 11.0 23.8 0.38 9.9 23.8 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000153.1_45722001_1 - 2.7e-108 361.8 20.6 3.3e-108 361.5 20.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000153.1_45722001_1 - 1.3e-20 73.6 14.8 2.8e-20 72.6 14.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000153.1_45722001_1 - 4e-06 26.3 11.8 1.4e-05 24.5 11.8 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM132D_C PF15706.3 001000153.1_45722001_1 - 0.19 11.4 2.0 0.4 10.4 2.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term 7tm_4 PF13853.4 001000448.1_45722001_1 - 3.1e-49 168.1 26.0 4.2e-49 167.6 26.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000448.1_45722001_1 - 3.3e-21 75.6 28.9 6.3e-21 74.7 28.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000448.1_45722001_1 - 0.0021 17.4 26.8 0.003 16.8 26.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000504.1_45722001_1 - 3.7e-61 207.2 24.3 4.5e-61 206.9 24.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000504.1_45722001_1 - 7.1e-26 90.9 19.9 2e-25 89.4 19.9 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000504.1_45722001_1 - 0.00026 20.3 17.3 0.00041 19.7 17.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000541.1_45722001_1 - 5.5e-101 337.8 14.5 6.3e-101 337.6 14.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000541.1_45722001_1 - 3.6e-17 62.4 11.8 1e-16 60.9 11.8 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000541.1_45722001_1 - 3.2e-09 36.4 2.3 3.2e-09 36.4 2.3 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000541.1_45722001_1 - 0.02 14.1 5.0 0.033 13.4 5.0 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Defensin_2 PF01097.16 001000541.1_45722001_3 - 8.4 6.3 11.1 1.9 8.4 2.7 2.7 2 0 0 2 2 2 0 Arthropod defensin 7tm_4 PF13853.4 001000372.1_45722001_1 - 1.9e-46 158.9 22.4 2.5e-46 158.5 22.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000372.1_45722001_1 - 1.4e-17 63.7 26.4 1.4e-17 63.7 26.4 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000352.1_45722001_1 - 1.6e-44 152.6 26.6 2e-44 152.3 26.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000352.1_45722001_1 - 7.9e-15 54.7 26.9 2.3e-14 53.1 26.9 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000039.1_45722001_1 - 4e-39 134.9 20.1 5.5e-39 134.4 20.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000039.1_45722001_1 - 1.2e-21 77.0 21.3 3.5e-21 75.5 21.3 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000039.1_45722001_1 - 0.00039 19.8 17.4 0.00074 18.8 17.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000039.1_45722001_1 - 0.0016 17.7 9.2 0.0016 17.7 9.2 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001000694.1_45722001_1 - 2.5e-37 129.0 27.0 3.2e-37 128.7 27.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000694.1_45722001_1 - 9.2e-20 70.9 31.2 2.3e-19 69.5 31.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000940.1_45722001_1 - 1e-48 166.4 23.7 1.4e-48 165.9 23.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000940.1_45722001_1 - 2.3e-21 76.1 26.7 5.2e-21 74.9 26.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CDRN PF05174.10 001000940.1_45722001_1 - 1.1 8.9 3.7 0.27 10.8 0.3 1.9 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus 7TM_GPCR_Srsx PF10320.7 001000940.1_45722001_1 - 1.2 8.3 31.4 11 5.2 30.8 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx YwiC PF14256.4 001000940.1_45722001_1 - 8.8 6.5 10.6 19 5.4 8.1 2.7 1 1 0 1 1 1 0 YwiC-like protein 7tm_4 PF13853.4 001000658.1_45722001_1 - 3.2e-45 154.9 13.5 3.8e-45 154.6 13.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000658.1_45722001_1 - 1.4e-19 70.3 15.1 3.6e-19 68.9 15.1 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3278 PF11683.6 001000658.1_45722001_1 - 0.59 10.1 4.5 3.2 7.7 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) 7tm_4 PF13853.4 001000141.1_45722001_1 - 7.1e-102 340.7 17.8 8.1e-102 340.6 17.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000141.1_45722001_1 - 3.8e-15 55.7 19.4 1.4e-14 53.9 19.4 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000141.1_45722001_1 - 1e-09 38.0 8.8 1e-09 38.0 8.8 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF5056 PF16479.3 001000141.1_45722001_1 - 0.12 12.5 0.5 0.31 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) 7tm_4 PF13853.4 001001371.1_45722001_1 - 2.5e-52 178.2 21.1 3.2e-52 177.9 21.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001371.1_45722001_1 - 6.5e-25 87.7 21.0 1.3e-24 86.7 21.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001371.1_45722001_1 - 0.0011 18.3 25.0 0.0018 17.6 25.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-RNPHF PF08080.10 001001371.1_45722001_1 - 0.07 13.0 0.4 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 RNPHF zinc finger Cadherin PF00028.15 001114601.1_45726001_2 - 1.1e-77 256.4 0.0 8.3e-17 61.3 0.0 6.2 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.10 001114601.1_45726001_2 - 1.2e-33 114.6 3.1 3.6e-33 113.1 0.1 3.3 5 0 0 5 5 5 1 Cadherin-like Cadherin_C_2 PF16492.3 001114601.1_45726001_2 - 1.3e-26 93.1 0.3 3e-26 91.9 0.3 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Cadherin_3 PF16184.3 001114601.1_45726001_2 - 4e-07 29.9 4.6 0.0044 16.9 0.1 4.9 4 0 0 4 4 4 2 Cadherin-like DUF3823 PF12866.5 001114601.1_45726001_2 - 0.0013 18.5 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3823) REJ PF02010.13 001114601.1_45726001_2 - 0.048 12.3 0.0 0.1 11.2 0.0 1.5 1 0 0 1 1 1 0 REJ domain Cache_3-Cache_2 PF17201.2 001114601.1_45726001_2 - 0.15 11.2 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain 7tm_4 PF13853.4 001000671.1_45722001_1 - 4.6e-46 157.7 20.1 5.5e-46 157.4 20.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000671.1_45722001_1 - 5.4e-21 74.9 20.9 2.2e-20 72.9 20.8 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000671.1_45722001_1 - 0.00019 20.8 22.0 0.00038 19.8 22.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PrgI PF12666.5 001000671.1_45722001_1 - 2.1 9.0 0.0 2.1 9.0 0.0 3.7 3 1 0 3 3 3 0 PrgI family protein 7tm_4 PF13853.4 001000911.1_45722001_1 - 5.2e-52 177.2 17.6 6.7e-52 176.8 17.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000911.1_45722001_1 - 5.2e-17 61.8 19.9 1.2e-16 60.6 19.9 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.20 001106151.2_45725001_1 - 4.4e-86 282.6 3.4 1.2e-21 76.2 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.16 001106151.2_45725001_1 - 5e-26 90.6 0.2 1.4e-25 89.2 0.1 1.8 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.4 001106151.2_45725001_1 - 2e-10 40.2 0.1 0.0075 15.7 0.0 4.4 1 1 3 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001106151.2_45725001_1 - 3.9e-06 26.6 0.1 2.4 8.1 0.0 4.5 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.6 001106151.2_45725001_1 - 3e-05 23.9 0.5 11 6.1 0.0 4.4 4 0 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.3 001106151.2_45725001_1 - 0.00013 21.6 0.0 0.33 10.7 0.0 3.6 4 0 0 4 4 4 1 Occluded RNA-recognition motif SET_assoc PF11767.6 001106151.2_45725001_1 - 0.00056 19.4 0.8 10 5.7 0.0 3.9 4 0 0 4 4 4 1 Histone lysine methyltransferase SET associated RRM_3 PF08777.9 001106151.2_45725001_1 - 0.0022 17.9 1.8 0.62 10.0 0.1 3.6 4 0 0 4 4 4 1 RNA binding motif RRM_7 PF16367.3 001106151.2_45725001_1 - 0.0025 17.7 0.2 15 5.7 0.0 4.4 3 2 1 4 4 4 0 RNA recognition motif ATP-grasp_2 PF08442.8 001106151.2_45725001_1 - 0.0049 16.3 0.2 3.3 7.1 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain HATPase_c PF02518.24 001106151.2_45725001_1 - 0.029 14.8 2.0 1 9.8 0.1 2.3 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YflT PF11181.6 001106151.2_45725001_1 - 0.075 13.4 0.3 7 7.1 0.1 2.8 3 0 0 3 3 3 0 Heat induced stress protein YflT OB_RNB PF08206.9 001106151.2_45725001_1 - 0.28 10.8 4.1 7 6.3 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain 7tm_4 PF13853.4 001001274.1_45722001_1 - 1.6e-120 401.9 18.7 1.9e-120 401.7 18.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001274.1_45722001_1 - 4.5e-18 65.3 13.2 1.5e-17 63.6 13.2 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001274.1_45722001_1 - 9.7e-08 31.6 3.2 9.7e-08 31.6 3.2 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001001274.1_45722001_1 - 0.57 9.3 14.8 0.049 12.8 7.7 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001000815.1_45722001_1 - 2.9e-48 164.9 21.5 3.7e-48 164.5 21.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000815.1_45722001_1 - 5.8e-23 81.4 23.2 9.8e-23 80.6 23.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000815.1_45722001_1 - 0.0006 19.1 21.6 0.00089 18.6 21.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000661.1_45722001_1 - 1e-43 150.0 20.2 1.3e-43 149.6 20.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000661.1_45722001_1 - 7.7e-18 64.5 21.2 1.6e-17 63.5 21.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000751.1_45722001_1 - 1.5e-47 162.5 16.9 1.9e-47 162.2 16.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000751.1_45722001_1 - 4.8e-19 68.5 24.7 8.5e-19 67.7 24.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000751.1_45722001_1 - 0.00038 19.8 23.3 0.0036 16.6 23.3 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000614.1_45722001_1 - 8.4e-49 166.6 23.5 9.8e-49 166.4 23.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000614.1_45722001_1 - 1.2e-20 73.8 22.3 6.5e-20 71.3 22.3 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001000513.1_45722001_1 - 3.4e-44 151.5 24.1 4e-44 151.3 24.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000513.1_45722001_1 - 1.4e-18 67.0 27.2 5.1e-18 65.1 27.2 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000513.1_45722001_1 - 4.5e-05 22.8 24.6 0.0068 15.7 24.4 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001001099.1_45722001_1 - 8.3e-49 166.7 20.3 9.6e-49 166.5 20.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001099.1_45722001_1 - 4.4e-22 78.5 22.1 7.7e-22 77.7 22.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001099.1_45722001_1 - 1.7e-06 27.5 23.6 8.3e-06 25.2 23.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000006.1_45722001_1 - 1.6e-46 159.2 21.8 2e-46 158.8 21.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000006.1_45722001_1 - 2.1e-27 95.9 24.8 4.7e-27 94.8 24.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000006.1_45722001_1 - 5.5e-07 29.1 19.4 7.8e-07 28.6 19.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx T4SS_CagC PF16943.3 001000006.1_45722001_1 - 0.26 11.4 0.1 0.26 11.4 0.1 1.9 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system 7tm_4 PF13853.4 001000902.1_45722001_1 - 1.9e-42 145.8 18.6 2.3e-42 145.5 18.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000902.1_45722001_1 - 2.1e-16 59.8 22.2 5e-16 58.6 22.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000902.1_45722001_1 - 2.7e-05 23.5 22.6 2.7e-05 23.5 22.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000410.1_45722001_1 - 4e-54 184.1 16.9 4.9e-54 183.8 16.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000410.1_45722001_1 - 1.1e-24 87.0 23.1 2.3e-24 86.0 23.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000410.1_45722001_1 - 4.7e-08 32.6 17.3 8.3e-08 31.8 17.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Glycoprotein_G PF00802.17 001000410.1_45722001_1 - 0.042 13.1 0.3 0.056 12.7 0.3 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G 7tm_4 PF13853.4 001001370.1_45722001_1 - 1.1e-48 166.3 22.5 1.4e-48 165.9 22.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001370.1_45722001_1 - 6.3e-21 74.7 26.4 1.9e-20 73.1 26.4 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gemini_mov PF01708.14 001001370.1_45722001_1 - 0.017 14.7 1.2 0.04 13.5 1.2 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Bap31 PF05529.10 001001370.1_45722001_1 - 2 7.8 7.3 1.3 8.5 4.9 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like 7tm_4 PF13853.4 001001289.1_45722001_1 - 2.1e-52 178.5 20.4 2.5e-52 178.2 20.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001289.1_45722001_1 - 2.2e-25 89.3 21.2 6.8e-25 87.7 21.2 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1298 PF06974.11 001001289.1_45722001_1 - 0.057 13.2 0.3 0.097 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) 7tm_4 PF13853.4 001001366.1_45722001_1 - 3.2e-51 174.6 21.5 4.1e-51 174.2 21.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001366.1_45722001_1 - 1.1e-23 83.7 24.0 2.1e-23 82.8 24.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001366.1_45722001_1 - 2.3e-05 23.8 25.8 3.6e-05 23.1 25.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-RNPHF PF08080.10 001001366.1_45722001_1 - 0.091 12.6 0.5 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 RNPHF zinc finger 7tm_4 PF13853.4 001000300.1_45722001_1 - 2.4e-56 191.4 16.6 2.8e-56 191.2 16.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000300.1_45722001_1 - 2.1e-24 86.1 18.1 3.7e-24 85.3 18.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2254 PF10011.7 001000300.1_45722001_1 - 0.016 14.0 0.9 0.016 14.0 0.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) 7tm_4 PF13853.4 001000124.1_45722001_1 - 1.8e-116 388.6 23.5 2e-116 388.4 23.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000124.1_45722001_1 - 9.6e-19 67.5 23.7 1.7e-18 66.7 23.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000124.1_45722001_1 - 7e-07 28.8 17.9 1.9e-06 27.3 17.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Epiglycanin_C PF14654.4 001000124.1_45722001_1 - 0.088 12.8 3.5 0.27 11.2 3.4 1.9 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region 7tm_4 PF13853.4 001000924.1_45722001_1 - 7e-48 163.6 22.2 9.4e-48 163.2 22.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000924.1_45722001_1 - 1.2e-16 60.6 24.7 3.9e-16 58.9 24.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SLC3A2_N PF16028.3 001000924.1_45722001_1 - 0.023 14.1 3.0 0.063 12.7 0.4 2.6 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.4 001001071.1_45722001_1 - 7.3e-53 180.0 19.4 9.4e-53 179.6 19.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001071.1_45722001_1 - 7.7e-24 84.2 25.6 1.7e-23 83.1 25.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001071.1_45722001_1 - 4.6e-08 32.6 22.1 9.1e-08 31.7 22.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Glycoprotein_G PF00802.17 001001071.1_45722001_1 - 0.053 12.7 0.4 0.077 12.2 0.4 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G 7tm_4 PF13853.4 001000770.1_45722001_1 - 1.2e-49 169.4 13.2 1.5e-49 169.1 13.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000770.1_45722001_1 - 1.8e-19 69.9 17.2 2.7e-19 69.3 17.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000770.1_45722001_1 - 2.6e-07 30.1 14.8 5.5e-07 29.1 14.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000770.1_45722001_1 - 0.00083 18.6 16.1 0.0018 17.5 16.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001001285.1_45722001_1 - 2.1e-111 372.0 25.5 2.4e-111 371.8 25.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001285.1_45722001_1 - 3.5e-22 78.8 22.8 1.7e-21 76.6 22.8 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001285.1_45722001_1 - 8.2e-05 22.0 17.1 0.00092 18.5 17.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000432.1_45722001_1 - 3e-57 194.4 23.0 3.4e-57 194.2 23.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000432.1_45722001_1 - 7.8e-25 87.5 20.7 1.6e-24 86.5 20.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000432.1_45722001_1 - 7.7e-06 25.3 19.8 2.6e-05 23.6 19.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001000481.1_45722001_1 - 5.1e-43 147.7 14.9 6.4e-43 147.4 14.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000481.1_45722001_1 - 2.1e-20 72.9 16.4 6.9e-20 71.3 16.4 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000481.1_45722001_1 - 0.0041 16.4 15.5 0.0068 15.7 15.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SLC3A2_N PF16028.3 001000481.1_45722001_1 - 0.18 11.3 1.2 1.2 8.6 0.3 2.4 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Sdh_cyt PF01127.20 001000481.1_45722001_1 - 4.3 7.3 10.1 0.65 9.9 3.8 2.6 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 7tm_4 PF13853.4 001000152.1_45722001_1 - 4e-98 328.4 23.0 5e-98 328.1 23.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000152.1_45722001_1 - 1.3e-16 60.5 23.1 3.1e-16 59.3 23.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000152.1_45722001_1 - 9.5e-06 25.0 18.2 1.3e-05 24.6 18.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx COX6C PF02937.13 037621.1_45722120_2 - 4e-32 110.0 0.1 6.1e-32 109.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc CRAM_rpt PF07016.9 037614.1_45725120_2 - 0.2 11.3 1.8 0.31 10.7 0.2 2.2 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor CSD PF00313.20 038098.1_45724120_3 - 1.6e-25 88.6 0.4 2.8e-25 87.8 0.4 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.9 038098.1_45724120_3 - 0.067 12.7 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease B OB domain PXPV PF12778.5 040598.1_32923120_2 - 0.058 13.1 1.3 0.058 13.1 1.3 2.4 3 0 0 3 3 3 0 PXPV repeat (3 copies) Ribosomal_60s PF00428.17 038063.1_32922120_3 - 3.3e-25 88.3 7.5 4.4e-25 87.9 7.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Tubulin PF00091.23 003964.2_32922120_2 - 5.3e-37 127.8 0.0 7e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.7 003964.2_32922120_2 - 0.00022 21.3 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain EMP24_GP25L PF01105.22 004052.1_32924120_1 - 3.1e-08 33.6 0.1 5e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EMP24_GP25L PF01105.22 004052.1_32924120_3 - 5.2e-08 32.9 0.9 1e-07 32.0 0.9 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TAS2R PF05296.11 001166751.1_32922001_1 - 2.3e-13 49.8 20.0 3e-13 49.4 20.0 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) V1R PF03402.12 001166751.1_32922001_1 - 1.4e-10 41.1 15.0 2.1e-10 40.5 15.0 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 001166751.1_32922001_1 - 1.3e-05 24.4 16.5 1.7e-05 24.1 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRP8_domainIV PF12134.6 001166751.1_32922001_1 - 0.093 12.2 1.1 0.54 9.7 0.1 2.4 2 1 1 3 3 3 0 PRP8 domain IV core V1R PF03402.12 030735.1_32923001_2 - 3.5e-16 59.5 13.5 7.4e-16 58.4 13.5 1.4 1 1 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R RhoGAP PF00620.25 040748.1_32927120_1 - 1.7e-07 31.0 0.0 3.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RhoGAP PF00620.25 040748.1_32927120_2 - 1.4e-10 41.0 0.3 0.00047 19.9 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain IPP-2 PF04979.12 033731.1_32924120_2 - 7.4e-24 84.8 5.3 1e-23 84.4 5.3 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Gp_dh_N PF00044.22 033633.1_32923120_1 - 4.5e-27 94.2 0.2 6.6e-27 93.7 0.2 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.18 033633.1_32923120_2 - 3.7e-50 169.4 0.0 4.8e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Ribosomal_L30 PF00327.18 033608.1_32922120_3 - 1.5e-11 43.9 0.3 3e-11 42.9 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.10 033608.1_32922120_3 - 8.5e-05 22.6 0.3 0.00014 21.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Kinesin PF00225.21 033597.1_32925120_1 - 7.3e-47 159.8 5.9 7e-26 90.8 0.4 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.3 033597.1_32925120_1 - 2.9e-15 56.4 0.3 4.7e-15 55.7 0.3 1.3 1 0 0 1 1 1 1 Microtubule binding Macro PF01661.19 003523.1_32924120_3 - 2.3e-23 82.4 0.0 4e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.3 003523.1_32924120_3 - 1.4e-12 46.9 0.1 1.4e-12 46.9 0.1 3.2 3 1 0 3 3 3 1 C-terminus of histone H2A Histone PF00125.22 003523.1_32924120_3 - 1.7e-11 44.5 0.1 1.7e-11 44.5 0.1 3.0 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 003523.1_32924120_3 - 0.0019 18.3 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 7tm_4 PF13853.4 146852.2_32922001_1 - 7.8e-53 179.9 15.1 9.5e-53 179.6 15.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146852.2_32922001_1 - 3.2e-21 75.6 21.6 8.8e-21 74.2 21.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 146852.2_32922001_1 - 3.6e-06 26.4 19.1 3.6e-06 26.4 19.1 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 146891.2_32923001_3 - 1.4e-46 159.4 23.2 1.9e-46 158.9 23.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146891.2_32923001_3 - 3.7e-15 55.8 24.7 1.3e-14 54.0 24.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 146891.2_32923001_3 - 0.013 14.7 31.9 1.7 7.8 31.9 3.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 146923.2_32923001_1 - 1e-60 205.8 23.0 1.2e-60 205.5 23.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146923.2_32923001_1 - 3.9e-26 91.7 24.4 9.5e-26 90.5 24.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 146923.2_32923001_1 - 9e-06 25.1 21.7 1.6e-05 24.3 21.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx BCD PF15461.4 146923.2_32923001_1 - 0.0021 17.4 6.7 0.0021 17.4 6.7 1.6 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase 7TM_GPCR_Srx PF10328.7 146923.2_32923001_1 - 0.014 14.6 20.8 0.039 13.1 20.8 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 146802.2_32923001_2 - 2.2e-47 162.0 25.9 3.2e-47 161.5 25.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146802.2_32923001_2 - 8.3e-19 67.7 30.3 1.4e-18 67.0 30.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 147032.2_32922001_1 - 1.4e-45 156.0 15.5 1.8e-45 155.7 15.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 147032.2_32922001_1 - 3.3e-26 92.0 16.3 6.1e-26 91.1 16.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 147032.2_32922001_1 - 8.6e-06 25.2 12.9 1.3e-05 24.6 12.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 147032.2_32922001_1 - 0.2 10.8 9.5 0.5 9.5 9.5 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 146447.1_32922001_1 - 3.8e-36 125.1 17.3 5.2e-36 124.7 17.3 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146447.1_32922001_1 - 1.8e-18 66.6 24.8 1.8e-18 66.6 24.8 2.1 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 146396.1_32922001_1 - 1.6e-49 169.0 25.6 1.9e-49 168.8 25.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146396.1_32922001_1 - 6.8e-20 71.3 25.6 2.7e-19 69.3 25.6 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 146396.1_32922001_1 - 0.00064 19.0 27.6 0.0012 18.2 27.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 146991.1_32922001_1 - 1.9e-47 162.2 20.5 2.2e-47 162.0 20.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146991.1_32922001_1 - 7.7e-20 71.1 22.9 1.5e-19 70.2 22.9 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 146991.1_32922001_1 - 2.2e-05 23.8 22.2 0.0002 20.7 22.2 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 147109.1_32922001_1 - 1e-139 464.9 22.0 1.1e-139 464.7 22.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 147109.1_32922001_1 - 1.2e-21 77.0 17.3 2.2e-21 76.2 17.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 147109.1_32922001_1 - 3.6e-06 26.4 16.6 8.2e-06 25.2 16.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 147028.2_32922001_1 - 4.7e-51 174.0 19.6 5.5e-51 173.8 19.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 147028.2_32922001_1 - 1.3e-20 73.6 20.6 2.6e-20 72.7 20.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.20 001166639.1_32922001_1 - 3.6e-13 49.0 0.0 5.8e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYTT PF07078.9 001166639.1_32922001_1 - 3.3e-05 23.3 0.1 3.3e-05 23.3 0.1 2.4 2 0 0 2 2 1 1 Forty-two-three protein Coilin_N PF15862.3 001166639.1_32922001_1 - 0.0024 17.5 11.2 0.0041 16.8 11.2 1.5 1 0 0 1 1 1 1 Coilin N-terminus DDHD PF02862.15 001166639.1_32922001_1 - 0.003 17.6 11.9 0.004 17.2 11.9 1.2 1 0 0 1 1 1 1 DDHD domain CPSF100_C PF13299.4 001166639.1_32922001_1 - 0.0057 16.7 8.0 0.0086 16.1 8.0 1.3 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.11 001166639.1_32922001_1 - 0.0072 16.9 14.0 0.024 15.2 14.5 1.7 2 0 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Borrelia_P83 PF05262.9 001166639.1_32922001_1 - 0.06 11.7 11.9 0.067 11.5 11.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SID-1_RNA_chan PF13965.4 001166639.1_32922001_1 - 0.078 11.3 2.1 0.083 11.2 2.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1192 PF06698.9 001166639.1_32922001_1 - 0.092 12.7 0.3 0.24 11.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) NPR3 PF03666.11 001166639.1_32922001_1 - 0.11 11.1 15.6 0.14 10.8 15.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gti1_Pac2 PF09729.7 001166639.1_32922001_1 - 0.32 10.9 15.5 0.59 10.0 15.5 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family eIF-3_zeta PF05091.10 001166639.1_32922001_1 - 0.35 9.6 20.0 0.44 9.3 20.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.6 001166639.1_32922001_1 - 0.37 10.6 5.8 0.55 10.0 5.8 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF1510 PF07423.9 001166639.1_32922001_1 - 0.56 9.5 21.8 0.79 9.0 21.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF913 PF06025.10 001166639.1_32922001_1 - 0.81 8.5 8.4 1 8.2 8.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2360 PF10152.7 001166639.1_32922001_1 - 0.84 9.9 18.4 1.3 9.3 18.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) FAM60A PF15396.4 001166639.1_32922001_1 - 0.99 9.2 13.1 1.5 8.7 13.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MAJIN PF15077.4 001166639.1_32922001_1 - 1.7 8.4 13.4 2.5 7.8 13.4 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein SpoIIP PF07454.9 001166639.1_32922001_1 - 1.8 7.8 19.5 2.6 7.3 19.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4407 PF14362.4 001166639.1_32922001_1 - 2 7.6 15.8 2.9 7.0 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_U57 PF05582.10 001166639.1_32922001_1 - 2 7.5 13.3 2.8 7.0 13.3 1.2 1 0 0 1 1 1 0 YabG peptidase U57 TFIIA PF03153.11 001166639.1_32922001_1 - 2.3 8.0 38.5 3.2 7.5 38.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.4 001166639.1_32922001_1 - 2.6 7.8 24.3 4.3 7.1 24.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.10 001166639.1_32922001_1 - 2.7 7.6 21.5 3.9 7.1 21.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.6 001166639.1_32922001_1 - 3.1 6.3 16.6 4.4 5.9 16.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3306 PF11748.6 001166639.1_32922001_1 - 4.2 8.1 17.1 8 7.2 17.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF2052 PF09747.7 001166639.1_32922001_1 - 4.4 7.3 25.0 6.5 6.7 25.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) LMBR1 PF04791.14 001166639.1_32922001_1 - 4.7 5.8 4.2 5 5.8 4.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HemX PF04375.12 001166639.1_32922001_1 - 5.1 6.2 34.1 7.5 5.6 34.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Presenilin PF01080.15 001166639.1_32922001_1 - 6.4 5.3 23.4 8.9 4.8 23.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1764 PF08576.8 001166639.1_32922001_1 - 9.2 7.0 19.8 3.2 8.5 17.1 1.6 2 0 0 2 2 1 0 Eukaryotic protein of unknown function (DUF1764) 7tm_3 PF00003.20 001103366.1_32926001_1 - 4.1e-59 200.1 25.7 4.1e-59 200.1 25.7 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001103366.1_32926001_1 - 1.2e-34 119.8 0.2 2.7e-34 118.7 0.2 1.4 1 1 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001103366.1_32926001_1 - 2.2e-17 62.6 13.3 2.2e-17 62.6 13.3 2.0 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR PNTB PF02233.14 001103366.1_32926001_1 - 0.015 14.1 1.7 0.028 13.2 1.7 1.4 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit 7tm_4 PF13853.4 146363.2_32922001_1 - 9.6e-50 169.7 28.4 1.1e-49 169.5 28.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146363.2_32922001_1 - 8.5e-17 61.1 32.4 5.4e-16 58.5 32.4 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 146363.2_32922001_1 - 0.048 12.9 32.5 0.07 12.4 31.9 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx V1R PF03402.12 134184.2_32922001_1 - 1.2e-55 188.8 21.1 1.5e-55 188.6 21.1 1.1 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7tm_1 PF00001.19 134184.2_32922001_1 - 0.014 14.5 22.0 0.02 14.0 22.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001011847.1_32922001_1 - 2.8e-104 348.7 17.9 3.2e-104 348.4 17.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001011847.1_32922001_1 - 7.9e-21 74.4 19.7 2e-20 73.0 19.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001011847.1_32922001_1 - 2.8e-07 30.0 12.0 5e-07 29.2 11.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 207554.1_32922001_1 - 7.4e-47 160.3 14.2 8.9e-47 160.0 14.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 207554.1_32922001_1 - 2.7e-19 69.3 17.7 9.8e-19 67.5 17.7 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 146390.1_32922001_1 - 9.5e-51 173.0 20.5 1.1e-50 172.8 20.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146390.1_32922001_1 - 2.6e-18 66.1 22.6 6.4e-18 64.8 22.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 146519.1_32922001_1 - 1.5e-47 162.6 19.2 1.7e-47 162.4 19.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 146519.1_32922001_1 - 2e-21 76.3 22.8 4.1e-21 75.3 22.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 146519.1_32922001_1 - 1.4e-06 27.8 18.5 1.2e-05 24.6 18.5 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-H2C2_2 PF13465.4 001100416.2_32926001_1 - 0.11 12.8 2.3 3.7 8.0 0.2 3.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-H2C2_2 PF13465.4 001100416.2_32926001_2 - 5.4e-119 383.7 137.5 1.3e-09 37.9 2.6 19.0 19 0 0 19 19 19 15 Zinc-finger double domain zf-C2H2 PF00096.24 001100416.2_32926001_2 - 5.8e-71 231.1 136.2 5.6e-06 26.4 0.4 18.5 19 0 0 19 19 18 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001100416.2_32926001_2 - 5.3e-43 141.8 131.8 0.00029 21.3 0.3 18.3 19 0 0 19 19 17 14 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001100416.2_32926001_2 - 5.4e-38 128.1 116.0 0.0002 21.1 0.3 16.4 17 0 0 17 17 17 14 C2H2-type zinc finger KRAB PF01352.25 001100416.2_32926001_2 - 5.1e-20 70.7 0.0 8.2e-20 70.1 0.0 1.3 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001100416.2_32926001_2 - 2.7e-14 52.9 78.0 0.016 15.2 3.6 10.8 1 1 13 14 14 14 13 Zinc ribbon domain XPA_N PF01286.16 001100416.2_32926001_2 - 3.1e-09 36.6 59.0 6.2 6.8 0.1 14.5 15 0 0 15 15 15 5 XPA protein N-terminal zf-C2H2_jaz PF12171.6 001100416.2_32926001_2 - 3.5e-08 33.4 97.9 0.074 13.3 0.2 15.5 15 0 0 15 15 15 8 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.6 001100416.2_32926001_2 - 7.1e-07 29.4 57.7 0.13 12.5 1.5 8.0 4 1 7 11 11 11 9 zinc-finger-containing domain C1_4 PF07975.10 001100416.2_32926001_2 - 1e-05 25.6 70.7 0.24 11.6 3.3 10.7 1 1 11 13 13 13 6 TFIIH C1-like domain zinc_ribbon_15 PF17032.3 001100416.2_32926001_2 - 1.3e-05 25.7 71.2 0.15 12.7 2.1 8.1 1 1 8 9 9 9 7 zinc-ribbon family zf-C2H2_11 PF16622.3 001100416.2_32926001_2 - 0.00063 19.3 70.4 0.24 11.0 0.0 13.8 15 0 0 15 15 15 5 zinc-finger C2H2-type FYVE PF01363.19 001100416.2_32926001_2 - 0.00076 19.4 79.4 0.15 12.1 11.7 8.3 1 1 7 8 8 8 3 FYVE zinc finger GATA PF00320.25 001100416.2_32926001_2 - 0.0036 16.7 58.4 2.9 7.5 0.1 12.6 9 2 5 14 14 14 2 GATA zinc finger zf-trcl PF13451.4 001100416.2_32926001_2 - 0.0067 16.2 63.6 4.4 7.1 0.0 13.6 13 2 0 13 13 13 2 Probable zinc-ribbon domain Csm1 PF12539.6 001100416.2_32926001_2 - 0.022 15.2 9.4 17 6.0 0.2 6.4 3 2 4 7 7 7 0 Chromosome segregation protein Csm1/Pcs1 Phage_Integr_2 PF13009.4 001100416.2_32926001_3 - 9.7e-05 21.5 4.8 9.7e-05 21.5 4.8 2.9 2 1 0 2 2 2 1 Putative phage integrase DUF5132 PF17195.2 001100416.2_32926001_3 - 0.0023 17.8 2.5 53 3.9 0.0 6.0 7 0 0 7 7 7 0 Protein of unknown function (DUF5132) zf-H2C2_2 PF13465.4 001100416.2_32926001_3 - 0.062 13.6 0.3 0.062 13.6 0.3 4.8 4 0 0 4 4 4 0 Zinc-finger double domain MarR PF01047.20 001100416.2_32926001_3 - 0.45 10.3 4.6 14 5.6 0.1 5.3 7 0 0 7 7 7 0 MarR family DUF3505 PF12013.6 001100416.2_32926001_3 - 0.95 9.8 20.9 5.1 7.4 0.5 6.3 3 2 2 6 6 6 0 Protein of unknown function (DUF3505) DUF285 PF03382.12 001100416.2_32926001_3 - 1 9.0 11.1 1.3 8.7 1.4 3.3 2 2 2 4 4 4 0 Mycoplasma protein of unknown function, DUF285 RVP_2 PF08284.9 001100416.2_32926001_3 - 1.1 9.2 6.2 1.5 8.7 0.1 3.8 3 1 2 5 5 5 0 Retroviral aspartyl protease DUF4777 PF16007.3 001100416.2_32926001_3 - 8.7 6.6 9.9 5.4 7.2 0.4 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4777) Lectin_C PF00059.19 001257248.1_08022001_3 - 2.2e-19 70.0 2.1 2.2e-19 70.0 2.1 1.6 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.10 001257248.1_08022001_3 - 0.00062 19.3 3.3 0.0012 18.4 3.3 1.5 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001257248.1_08022001_3 - 0.0018 17.5 1.0 0.0029 16.8 1.0 1.3 1 0 0 1 1 1 1 Chordopoxvirus A33R protein V-set_2 PF15910.3 001257219.1_08022001_1 - 2.4e-14 53.2 1.0 3.4e-14 52.8 1.0 1.2 1 0 0 1 1 1 1 ICOS V-set domain V-set PF07686.15 001257219.1_08022001_1 - 0.00068 19.6 0.2 0.0011 18.9 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain IL4 PF00727.16 001257228.1_08022001_2 - 2e-45 153.4 6.8 2.5e-45 153.1 6.8 1.1 1 0 0 1 1 1 1 Interleukin 4 Mannosyl_trans3 PF11051.6 001257228.1_08022001_2 - 0.042 13.0 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative DNA_III_psi PF03603.11 001257228.1_08022001_2 - 0.044 13.9 0.9 0.063 13.4 0.7 1.3 1 1 0 1 1 1 0 DNA polymerase III psi subunit Lectin_C PF00059.19 001267770.1_08022001_1 - 7e-22 78.1 4.4 1.1e-21 77.5 4.4 1.3 1 0 0 1 1 1 1 Lectin C-type domain SH2 PF00017.22 001123196.1_49822001_1 - 2.5e-10 40.2 0.0 4.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.14 001123196.1_49822001_1 - 4.1e-05 23.7 0.0 9.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 SOCS box Orn_Arg_deC_N PF02784.14 001301734.1_22429001_3 - 2e-63 214.0 0.1 2.5e-63 213.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301734.1_22429001_3 - 3.3e-24 85.0 0.0 6e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001301735.1_24229001_3 - 1.5e-63 214.4 0.1 1.8e-63 214.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301735.1_24229001_3 - 2.9e-24 85.2 0.0 5.2e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291502.1_22429001_1 - 1.9e-63 214.1 0.1 2.4e-63 213.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291502.1_22429001_1 - 3.1e-24 85.0 0.0 5.7e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.14 001291511.1_24229001_2 - 1.5e-63 214.4 0.1 1.9e-63 214.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001291511.1_24229001_2 - 2.9e-24 85.1 0.0 5.4e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain IL5 PF02025.13 001257233.1_08021001_1 - 1.2e-58 196.1 0.4 1.4e-58 195.9 0.4 1.0 1 0 0 1 1 1 1 Interleukin 5 NuiA PF07924.9 001257233.1_08021001_1 - 0.062 13.6 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein 7tm_4 PF13853.4 001000710.1_45722001_1 - 3.2e-44 151.6 28.3 3.8e-44 151.4 28.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000710.1_45722001_1 - 4.2e-23 81.8 30.9 2.4e-22 79.3 30.9 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000710.1_45722001_1 - 0.00086 18.6 26.1 0.0019 17.5 26.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000710.1_45722001_1 - 0.38 9.9 32.0 0.26 10.4 29.7 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Frizzled PF01534.15 001168992.1_40424001_1 - 9e-144 478.3 11.5 1.1e-143 478.0 11.5 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.20 001168992.1_40424001_1 - 6.9e-33 113.6 4.3 6.9e-33 113.6 4.3 1.6 2 0 0 2 2 2 1 Fz domain 7tm_2 PF00002.22 001168992.1_40424001_1 - 5.6e-06 25.7 8.5 1.1e-05 24.8 8.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.9 001168992.1_40424001_1 - 0.00014 21.0 4.3 0.00027 20.0 4.3 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF5083 PF16890.3 001168992.1_40424001_1 - 0.14 11.9 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) zf-DHHC PF01529.18 001168992.1_40424001_1 - 1.7 8.6 7.7 2.2 8.3 1.5 3.2 1 1 2 3 3 3 0 DHHC palmitoyltransferase Ank_2 PF12796.5 001168761.1_40424001_1 - 4.2e-11 43.1 0.0 7.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001168761.1_40424001_1 - 1.4e-10 41.3 2.0 2e-06 28.1 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.4 001168761.1_40424001_1 - 1.9e-10 40.7 1.6 2.7e-07 30.7 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.28 001168761.1_40424001_1 - 7.8e-09 35.5 0.4 0.00023 21.4 0.4 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.4 001168761.1_40424001_1 - 2.4e-08 33.4 0.1 0.0092 16.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Tubulin PF00091.23 001328304.1_39724001_3 - 1.6e-67 227.4 0.0 2.1e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001328304.1_39724001_3 - 3.1e-51 172.7 0.0 4.9e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001328304.1_39724001_3 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain HSP70 PF00012.18 001328303.1_39726001_2 - 2.7e-260 864.6 4.4 3.1e-260 864.4 4.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001328303.1_39726001_2 - 3.5e-16 58.8 0.1 1.3e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.4 001328303.1_39726001_2 - 0.0012 19.1 0.6 8.8 6.7 0.0 3.5 3 0 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.14 001328303.1_39726001_2 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.9 001328303.1_39726001_2 - 0.059 12.5 3.5 0.12 11.5 3.5 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Peptidase_M48 PF01435.16 001328312.1_39724001_3 - 4.9e-28 98.1 0.0 7.3e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Sulf_transp PF04143.12 001328312.1_39724001_3 - 0.041 13.3 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Sulphur transport DUF4660 PF15559.4 024113.1_26227120_1 - 3.4e-20 72.2 1.1 6.2e-20 71.4 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4660) DUF4660 PF15559.4 024113.1_26227120_2 - 9.6e-10 38.6 0.2 9.6e-10 38.6 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4660) NPIP PF06409.9 001328307.1_39724001_1 - 1.5e-114 381.6 82.0 5.7e-62 209.2 4.0 7.5 2 1 5 7 7 7 6 Nuclear pore complex interacting protein (NPIP) Lectin_C PF00059.19 001328302.1_39723001_1 - 3.6e-09 37.2 0.2 3.6e-09 37.2 0.2 1.6 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.10 001328302.1_39723001_1 - 0.00016 21.3 0.1 0.00026 20.6 0.1 1.5 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like YL1 PF05764.11 001171300.1_37923001_1 - 9.6e-54 182.9 14.6 1.3e-53 182.5 14.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.9 001171300.1_37923001_1 - 1.5e-12 46.9 0.6 2.9e-12 46.0 0.6 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Osteopontin PF00865.16 001171300.1_37923001_1 - 7 5.9 13.8 1.1 8.6 9.7 1.6 1 1 1 2 2 2 0 Osteopontin Spb1_C PF07780.10 001171300.1_37923001_2 - 0.13 11.8 0.6 0.18 11.3 0.6 1.1 1 0 0 1 1 1 0 Spb1 C-terminal domain Aldo_ket_red PF00248.19 001171057.1_37923001_1 - 6.2e-74 248.6 0.0 7.2e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TGF_beta PF00019.18 001171489.1_37923001_1 - 1.5e-14 54.6 0.1 4.3e-14 53.1 0.1 1.7 1 1 0 1 1 1 1 Transforming growth factor beta like domain Serpin PF00079.18 001171287.1_37923001_1 - 6.3e-126 420.5 7.9 7.3e-126 420.3 7.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF2027 PF09640.8 001171287.1_37923001_1 - 0.023 14.2 0.4 5.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2027) Ion_trans PF00520.29 001171129.1_37924001_1 - 2.7e-52 177.3 4.4 3.6e-52 176.9 4.4 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001171129.1_37924001_1 - 1.9e-28 98.5 0.0 3.4e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001171129.1_37924001_1 - 2e-13 49.9 6.3 2e-13 49.9 6.3 2.4 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.10 001171129.1_37924001_1 - 0.0016 17.1 0.6 0.0027 16.3 0.6 1.4 1 0 0 1 1 1 1 Polycystin cation channel TFIIA PF03153.11 001204847.1_37924001_3 - 1.9e-122 410.2 0.0 2.1e-122 410.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Claudin_2 PF13903.4 001171389.1_37922001_1 - 4.2e-21 75.5 1.8 6.1e-21 74.9 1.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.18 001171389.1_37922001_1 - 3.5e-20 72.4 1.8 7.2e-20 71.4 1.8 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.9 001171389.1_37922001_1 - 0.007 16.1 0.4 0.011 15.5 0.1 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein Claudin_3 PF06653.9 001171389.1_37922001_1 - 0.0086 15.9 3.5 0.058 13.2 0.6 2.1 2 0 0 2 2 2 1 Tight junction protein, Claudin-like DUF716 PF04819.10 001171389.1_37922001_1 - 0.0087 15.7 0.2 0.018 14.7 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF716) L_HMGIC_fpl PF10242.7 001171389.1_37922001_1 - 0.015 15.4 0.7 0.022 14.8 0.7 1.3 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF4064 PF13273.4 001171389.1_37922001_1 - 0.19 12.0 3.5 1.3 9.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF202 PF02656.13 001171389.1_37922001_1 - 1.2 9.5 7.0 0.16 12.3 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Serpin PF00079.18 001171283.1_37923001_1 - 3.1e-122 408.3 0.3 3.5e-122 408.1 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Lip_prot_lig_C PF10437.7 001171283.1_37923001_1 - 0.021 14.7 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Ion_trans PF00520.29 001082182.1_37924001_3 - 6.1e-45 153.2 13.6 7.6e-45 152.9 13.6 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001082182.1_37924001_3 - 6.7e-28 96.8 0.0 1.7e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001082182.1_37924001_3 - 4.3e-11 42.5 2.7 4.3e-11 42.5 2.7 2.5 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.3 001082182.1_37924001_3 - 0.0031 17.5 0.0 0.0077 16.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.29 001082676.2_37925001_1 - 4.8e-48 163.4 10.3 6.4e-48 163.0 10.3 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001082676.2_37925001_1 - 2.7e-28 98.0 0.1 5.8e-28 97.0 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001082676.2_37925001_1 - 1.5e-13 50.4 4.8 1.5e-13 50.4 4.8 2.6 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.10 001082676.2_37925001_1 - 0.0012 17.5 0.2 0.0012 17.5 0.2 1.8 1 1 1 2 2 2 1 Polycystin cation channel GM_CSF PF01109.15 001171257.1_37921001_1 - 8.1e-60 200.2 0.4 9.2e-60 200.1 0.4 1.0 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor PI3_PI4_kinase PF00454.25 001171303.1_37925001_1 - 3.9e-34 118.4 0.2 3.6e-31 108.8 0.2 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.4 001171303.1_37925001_1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TMEM215 PF15746.3 001171303.1_37925001_1 - 0.13 11.6 0.1 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 TMEM215 family 7tm_1 PF00001.19 001135128.1_37923001_1 - 5.1e-50 170.1 19.5 1.3e-49 168.7 19.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001135128.1_37923001_1 - 1.9e-06 27.3 16.9 2.4e-06 27.0 16.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LysM PF01476.18 001171297.1_37922001_1 - 1.3e-08 34.7 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain Serpin PF00079.18 001171154.1_37923001_1 - 2.8e-130 434.8 0.4 3.2e-130 434.6 0.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) GDE_C PF06202.12 001171154.1_37923001_1 - 0.063 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase ISK_Channel PF02060.13 001089314.2_37922001_2 - 5e-08 32.6 0.0 8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Slow voltage-gated potassium channel Sushi PF00084.18 001082755.1_37926001_3 - 1.6e-43 147.0 57.3 6.8e-10 39.3 3.2 6.8 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) Lectin_C PF00059.19 001082755.1_37926001_3 - 1.7e-19 70.4 7.1 1.7e-19 70.4 7.1 2.4 2 0 0 2 2 2 1 Lectin C-type domain EGF_2 PF07974.11 001082755.1_37926001_3 - 6.5e-05 23.1 9.4 0.0006 20.0 9.4 2.9 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.25 001082755.1_37926001_3 - 0.00025 21.2 8.7 0.00025 21.2 8.7 4.3 2 0 0 2 2 2 1 EGF-like domain EGF_3 PF12947.5 001082755.1_37926001_3 - 0.0062 16.6 4.7 0.0062 16.6 4.7 3.9 5 0 0 5 5 5 1 EGF domain Plasmod_Pvs28 PF06247.9 001082755.1_37926001_3 - 0.016 15.4 4.8 0.087 13.0 4.8 2.4 1 0 0 1 1 1 0 Pvs28 EGF domain RasGEF PF00617.17 001171492.1_37924001_1 - 7.3e-39 133.6 0.0 1.8e-38 132.3 0.0 1.6 2 0 0 2 2 2 1 RasGEF domain EF-hand_1 PF00036.30 001171492.1_37924001_1 - 1.2e-11 43.1 0.8 1.1e-05 24.5 0.2 2.9 2 0 0 2 2 2 2 EF hand C1_1 PF00130.20 001171492.1_37924001_1 - 4.8e-11 42.2 7.9 8.9e-11 41.4 7.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_6 PF13405.4 001171492.1_37924001_1 - 6.9e-11 41.1 0.2 4.5e-05 22.9 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.4 001171492.1_37924001_1 - 2.8e-10 39.1 0.7 6.2e-06 25.4 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 001171492.1_37924001_1 - 1.1e-09 38.5 0.1 0.0006 20.1 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain pair RasGEF_N PF00618.18 001171492.1_37924001_1 - 2.3e-09 37.3 0.1 1.9e-07 31.1 0.0 2.8 3 0 0 3 3 3 1 RasGEF N-terminal motif EF-hand_8 PF13833.4 001171492.1_37924001_1 - 3.4e-05 23.4 1.9 0.0026 17.4 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001171492.1_37924001_1 - 0.037 14.2 0.1 3.5 7.8 0.1 2.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region IRK PF01007.18 001198930.1_37923001_1 - 9.5e-134 445.4 0.0 1.1e-133 445.2 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF2182 PF09948.7 001198930.1_37923001_1 - 0.036 13.8 1.0 0.064 13.0 1.0 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) Ion_trans_2 PF07885.14 001198930.1_37923001_1 - 0.044 13.6 3.6 0.12 12.3 3.6 1.8 1 1 0 1 1 1 0 Ion channel Fascin PF06268.11 001171280.1_37923001_1 - 1.1e-63 212.2 0.3 3e-27 94.9 0.0 4.3 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.10 001171280.1_37923001_1 - 8.6e-10 38.5 0.0 0.014 15.0 0.0 5.1 3 2 2 5 5 5 4 FRG1-like domain DUF569 PF04601.11 001171280.1_37923001_1 - 0.011 15.3 0.1 0.68 9.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF569) Filament PF00038.19 001099963.1_37923001_2 - 2.8e-54 184.7 15.2 3.5e-54 184.4 15.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein KASH_CCD PF14662.4 001099963.1_37923001_2 - 0.0035 17.1 7.0 0.0035 17.1 7.0 3.0 3 0 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH MCPVI PF02993.12 001099963.1_37923001_2 - 0.013 15.2 0.7 0.013 15.2 0.7 2.2 2 1 0 2 2 2 0 Minor capsid protein VI TBPIP PF07106.11 001099963.1_37923001_2 - 0.45 10.1 7.9 6.6 6.3 2.2 2.9 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF812 PF05667.9 001099963.1_37923001_2 - 0.48 9.1 17.2 4.6 5.9 17.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF948 PF06103.9 001099963.1_37923001_2 - 0.86 9.8 2.6 37 4.5 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.6 001099963.1_37923001_2 - 1.5 8.9 21.6 2.1 8.5 0.9 4.1 3 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding FTA4 PF13093.4 001099963.1_37923001_2 - 2.4 7.9 7.3 0.86 9.3 3.9 2.0 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4140 PF13600.4 001099963.1_37923001_2 - 3.5 8.0 13.2 3.8 7.9 0.6 3.6 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Bap31 PF05529.10 001099963.1_37923001_2 - 4.8 6.6 12.3 1.8 8.0 0.8 2.5 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like Spc7 PF08317.9 001099963.1_37923001_2 - 8.7 5.0 18.8 3.1 6.5 6.8 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein RFX5_DNA_bdg PF14621.4 001171491.1_37924001_1 - 3.2e-93 311.4 26.8 3.2e-93 311.4 26.8 2.0 2 0 0 2 2 2 1 RFX5 DNA-binding domain RFX_DNA_binding PF02257.13 001171491.1_37924001_1 - 5.9e-29 100.4 0.9 8.9e-29 99.8 0.9 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.14 001171491.1_37924001_1 - 0.00092 19.5 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Poxvirus D5 protein-like RAP1 PF07218.9 001171491.1_37924001_1 - 0.72 7.9 7.0 1 7.4 7.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ion_trans PF00520.29 001199008.1_37924001_1 - 7.3e-50 169.3 7.0 1e-49 168.8 7.0 1.2 1 0 0 1 1 1 1 Ion transport protein K_channel_TID PF07941.9 001199008.1_37924001_1 - 4.5e-38 129.5 20.6 4.5e-38 129.5 20.6 2.1 3 0 0 3 3 3 1 Potassium channel Kv1.4 tandem inactivation domain BTB_2 PF02214.20 001199008.1_37924001_1 - 4.6e-28 97.3 0.1 1.1e-27 96.1 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001199008.1_37924001_1 - 3.8e-13 49.1 5.4 3.8e-13 49.1 5.4 2.5 3 0 0 3 3 3 1 Ion channel Sigma_reg_N PF13800.4 001199008.1_37924001_1 - 0.032 14.4 1.8 4.5 7.5 0.0 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal PKD_channel PF08016.10 001199008.1_37924001_1 - 0.98 7.9 8.4 0.02 13.5 1.6 1.5 2 0 0 2 2 2 0 Polycystin cation channel DctQ PF04290.10 001199008.1_37924001_1 - 3.3 7.5 6.8 0.31 10.8 0.7 2.4 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Connexin PF00029.17 001198960.1_37924001_1 - 1.5e-82 276.6 8.8 2.3e-82 276.0 8.8 1.3 1 0 0 1 1 1 1 Connexin 7tm_1 PF00001.19 001198935.1_37923001_1 - 3.4e-88 295.2 0.0 4.1e-88 295.0 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001198935.1_37923001_1 - 6.7e-13 48.5 3.9 9.3e-08 31.6 1.7 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001198935.1_37923001_1 - 3.9e-06 26.7 5.8 7.7e-05 22.4 1.4 2.8 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001198935.1_37923001_1 - 2.6e-05 23.6 2.2 2.6e-05 23.6 2.2 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Connexin PF00029.17 001198964.1_37923001_1 - 1e-95 319.7 0.8 1.2e-95 319.4 0.8 1.1 1 0 0 1 1 1 1 Connexin Connexin40_C PF16791.3 001198964.1_37923001_1 - 3.1e-34 118.3 0.2 5.8e-34 117.4 0.2 1.5 1 0 0 1 1 1 1 Connexin 40 C-terminal domain Aldo_ket_red PF00248.19 001171058.1_37923001_1 - 5.6e-74 248.8 0.0 6.5e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GSHPx PF00255.17 001256906.1_37922001_2 - 5.5e-41 138.4 0.8 7.4e-41 138.0 0.8 1.2 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.17 001256893.1_37923001_3 - 6.5e-40 134.9 0.2 8.3e-40 134.6 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AAA_23 PF13476.4 001171348.1_37928001_1 - 2e-33 116.5 1.6 2e-33 116.5 1.6 9.7 2 1 7 9 9 3 1 AAA domain Rad50_zn_hook PF04423.12 001171348.1_37928001_1 - 1.5e-12 47.0 0.1 1.5e-12 47.0 0.1 6.9 7 0 0 7 7 7 1 Rad50 zinc hook motif AAA_21 PF13304.4 001171348.1_37928001_1 - 1.5e-09 38.0 0.3 2e-05 24.4 0.0 5.7 3 2 2 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.4 001171348.1_37928001_1 - 1.6e-07 31.2 14.4 1.6e-07 31.2 14.4 5.3 1 1 3 4 4 2 2 AAA ATPase domain SbcCD_C PF13558.4 001171348.1_37928001_1 - 7.8e-07 29.1 0.2 2.9e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.17 001171348.1_37928001_1 - 1.1e-05 24.9 0.0 1.1e-05 24.9 0.0 3.7 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.4 001171348.1_37928001_1 - 0.0034 16.9 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2703 PF10865.6 001171348.1_37928001_1 - 0.022 14.8 0.6 0.022 14.8 0.6 6.1 5 1 3 8 8 8 0 Domain of unknown function (DUF2703) AAA_16 PF13191.4 001171348.1_37928001_1 - 0.25 11.5 0.0 0.25 11.5 0.0 5.3 4 1 1 5 5 4 0 AAA ATPase domain Reo_sigmaC PF04582.10 001171348.1_37928001_1 - 0.6 9.3 42.2 0.5 9.6 0.6 6.6 2 1 3 6 6 6 0 Reovirus sigma C capsid protein Erf4 PF10256.7 001171348.1_37928001_1 - 1.6 8.7 5.6 69 3.5 0.1 5.2 4 0 0 4 4 4 0 Golgin subfamily A member 7/ERF4 family DUF3015 PF11220.6 001171348.1_37928001_1 - 4.7 6.9 9.6 2.1 8.1 0.8 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3015) Cir_N PF10197.7 001171392.1_37922001_1 - 3.2e-07 30.3 8.9 3.2e-07 30.3 8.9 5.0 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Apolipoprotein PF01442.16 001171410.1_37923001_1 - 4.4e-61 206.1 22.2 1.8e-44 151.9 12.6 3.1 2 1 1 3 3 3 3 Apolipoprotein A1/A4/E domain YtxH PF12732.5 001171410.1_37923001_1 - 6.8e-09 36.0 15.2 0.014 15.7 0.0 6.7 1 1 2 3 3 3 2 YtxH-like protein ApoLp-III PF07464.9 001171410.1_37923001_1 - 2.8e-08 33.9 20.5 0.0016 18.4 1.3 4.0 1 1 0 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.10 001171410.1_37923001_1 - 8.9e-07 28.9 15.3 0.026 14.5 2.4 5.3 1 1 5 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.11 001171410.1_37923001_1 - 2.4e-05 24.7 13.6 1.5 9.3 0.3 5.8 1 1 5 7 7 7 3 Bacterial protein of unknown function (DUF883) OmpH PF03938.12 001171410.1_37923001_1 - 9.7e-05 22.3 9.9 9.7e-05 22.3 9.9 4.0 1 1 2 3 3 3 1 Outer membrane protein (OmpH-like) BshC PF10079.7 001171410.1_37923001_1 - 0.00025 19.8 19.3 0.049 12.3 0.5 3.1 1 1 2 3 3 3 2 Bacillithiol biosynthesis BshC Apo-CIII PF05778.10 001171410.1_37923001_1 - 0.00031 20.2 3.9 0.0097 15.4 0.7 3.1 3 0 0 3 3 3 1 Apolipoprotein CIII (Apo-CIII) ApoO PF09769.7 001171410.1_37923001_1 - 0.00039 20.3 8.1 0.14 12.0 0.0 5.2 2 2 4 6 6 6 1 Apolipoprotein O DUF445 PF04286.10 001171410.1_37923001_1 - 0.00053 19.8 12.7 0.013 15.2 3.5 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF445) DUF1640 PF07798.9 001171410.1_37923001_1 - 0.00076 19.4 19.6 0.71 9.8 1.4 3.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) ApoC-I PF04691.10 001171410.1_37923001_1 - 0.0014 18.4 8.8 0.0085 15.9 0.0 5.0 5 0 0 5 5 5 1 Apolipoprotein C-I (ApoC-1) Gp58 PF07902.9 001171410.1_37923001_1 - 0.0029 16.0 11.4 0.068 11.5 2.2 2.1 1 1 1 2 2 2 2 gp58-like protein SF-assemblin PF06705.9 001171410.1_37923001_1 - 0.0062 15.8 13.6 1.5 8.0 9.3 3.4 1 1 1 2 2 2 1 SF-assemblin/beta giardin Prominin PF05478.9 001171410.1_37923001_1 - 0.0062 14.4 15.1 0.0086 14.0 12.1 2.1 1 1 0 1 1 1 1 Prominin KapB PF08810.8 001171410.1_37923001_1 - 0.015 15.4 12.4 3.1 7.9 0.0 5.2 1 1 7 8 8 7 0 Kinase associated protein B Exonuc_VII_L PF02601.13 001171410.1_37923001_1 - 0.015 14.7 21.6 0.52 9.7 11.4 3.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF1845 PF08900.9 001171410.1_37923001_1 - 0.017 14.7 10.0 0.15 11.6 0.2 4.7 2 1 3 5 5 5 0 Domain of unknown function (DUF1845) YbaJ PF10757.7 001171410.1_37923001_1 - 0.022 15.2 0.8 0.19 12.2 0.0 2.6 1 1 2 3 3 3 0 Biofilm formation regulator YbaJ PhageMin_Tail PF10145.7 001171410.1_37923001_1 - 0.046 13.5 8.3 0.14 11.9 0.6 2.3 1 1 1 2 2 2 0 Phage-related minor tail protein DUF2884 PF11101.6 001171410.1_37923001_1 - 0.052 12.9 20.5 0.15 11.4 7.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2884) Flg_hook PF02120.14 001171410.1_37923001_1 - 0.054 13.3 14.8 2.8 7.8 0.2 5.0 1 1 4 5 5 5 0 Flagellar hook-length control protein FliK Ku_C PF03730.12 001171410.1_37923001_1 - 0.058 14.0 12.0 4.1 8.0 1.7 4.8 1 1 3 4 4 4 0 Ku70/Ku80 C-terminal arm RRF PF01765.17 001171410.1_37923001_1 - 0.06 13.2 12.7 0.092 12.6 0.2 3.5 1 1 1 3 3 3 0 Ribosome recycling factor Phe_ZIP PF08916.9 001171410.1_37923001_1 - 0.099 13.2 0.1 0.31 11.7 0.1 1.8 1 0 0 1 1 1 0 Phenylalanine zipper DUF842 PF05811.11 001171410.1_37923001_1 - 0.12 12.1 7.9 4.1 7.1 0.0 3.3 1 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) S-AdoMet_synt_M PF02772.14 001171410.1_37923001_1 - 0.13 12.4 1.0 4.5 7.4 0.5 3.4 2 1 0 2 2 2 0 S-adenosylmethionine synthetase, central domain Cnd1 PF12717.5 001171410.1_37923001_1 - 0.18 11.7 1.0 0.46 10.3 1.0 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 FliT PF05400.11 001171410.1_37923001_1 - 0.18 12.5 18.6 9.2 7.0 7.2 4.8 2 2 1 3 3 3 0 Flagellar protein FliT Phage_Mu_Gam PF07352.10 001171410.1_37923001_1 - 0.21 11.3 19.8 0.6 9.9 1.9 5.2 1 1 4 5 5 5 0 Bacteriophage Mu Gam like protein Fib_alpha PF08702.8 001171410.1_37923001_1 - 0.32 11.0 17.3 0.13 12.3 3.4 3.8 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family Ribosomal_S30AE PF02482.17 001171410.1_37923001_1 - 0.32 11.7 3.6 18 6.0 0.3 4.1 2 2 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF4611 PF15387.4 001171410.1_37923001_1 - 0.36 10.9 4.3 3.7 7.7 0.0 3.7 2 2 0 4 4 4 0 Domain of unknown function (DUF4611) AI-2E_transport PF01594.14 001171410.1_37923001_1 - 0.71 8.8 6.6 11 4.9 0.1 3.6 2 2 1 4 4 4 0 AI-2E family transporter Ribonuc_2-5A PF06479.10 001171410.1_37923001_1 - 0.77 9.8 8.1 0.61 10.1 1.4 3.3 2 1 0 3 3 3 0 Ribonuclease 2-5A Fzo_mitofusin PF04799.11 001171410.1_37923001_1 - 0.94 8.8 19.4 2.5 7.5 0.9 4.9 1 1 4 5 5 5 0 fzo-like conserved region ZYG-11_interact PF05884.10 001171410.1_37923001_1 - 1.4 8.1 14.2 1.3 8.2 4.0 4.0 1 1 1 3 3 3 0 Interactor of ZYG-11 DUF4407 PF14362.4 001171410.1_37923001_1 - 1.4 8.0 15.3 4.9 6.3 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ZnuA PF01297.15 001171410.1_37923001_1 - 1.9 7.7 7.2 20 4.3 1.3 3.8 1 1 1 3 3 3 0 Zinc-uptake complex component A periplasmic FUSC PF04632.10 001171410.1_37923001_1 - 3.1 6.1 6.5 11 4.3 2.3 2.5 1 1 2 3 3 3 0 Fusaric acid resistance protein family SAC3_GANP PF03399.14 001171396.1_37925001_1 - 7.9e-27 94.3 0.1 2.7e-25 89.2 0.1 2.2 1 1 0 1 1 1 1 SAC3/GANP family DUF4148 PF13663.4 001171396.1_37925001_1 - 0.14 12.2 1.7 0.42 10.7 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Apolipoprotein PF01442.16 001171409.1_37923001_1 - 2.8e-59 200.2 18.0 1.6e-57 194.5 10.3 2.9 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain BcrAD_BadFG PF01869.18 001171409.1_37923001_1 - 0.0013 18.2 0.0 0.061 12.7 0.0 2.5 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Translin PF01997.14 001171409.1_37923001_1 - 0.002 18.0 1.4 0.0048 16.8 1.4 1.7 1 1 0 1 1 1 1 Translin family Exonuc_VII_L PF02601.13 001171409.1_37923001_1 - 0.0026 17.3 11.0 0.35 10.3 0.1 2.3 1 1 1 2 2 2 2 Exonuclease VII, large subunit Gp-FAR-1 PF05823.10 001171409.1_37923001_1 - 0.0029 17.8 0.7 1.3 9.2 0.3 2.5 2 1 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF883 PF05957.11 001171409.1_37923001_1 - 0.0055 17.1 12.0 0.029 14.8 0.8 4.5 2 1 3 5 5 4 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.5 001171409.1_37923001_1 - 0.0071 16.7 0.8 0.36 11.3 0.0 3.6 3 2 0 3 3 2 1 YtxH-like protein Prominin PF05478.9 001171409.1_37923001_1 - 0.015 13.2 1.0 0.043 11.6 0.2 1.8 1 1 1 2 2 2 0 Prominin Serine_rich PF08824.8 001171409.1_37923001_1 - 0.019 14.9 3.7 0.054 13.4 0.2 2.5 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF948 PF06103.9 001171409.1_37923001_1 - 0.02 15.0 2.0 3.6 7.8 0.0 4.2 3 1 2 5 5 4 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.9 001171409.1_37923001_1 - 0.024 14.6 0.1 0.024 14.6 0.1 3.6 2 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.10 001171409.1_37923001_1 - 0.054 13.4 8.9 1.4 8.8 1.0 4.8 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.6 001171409.1_37923001_1 - 0.067 13.4 0.4 0.39 10.9 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF812 PF05667.9 001171409.1_37923001_1 - 0.083 11.6 10.4 0.063 12.0 6.9 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF812) DUF1014 PF06244.10 001171409.1_37923001_1 - 0.14 12.6 1.4 0.4 11.2 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1014) ZnuA PF01297.15 001171409.1_37923001_1 - 0.18 11.0 0.5 1.1 8.5 0.5 2.1 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic DUF479 PF04336.10 001171409.1_37923001_1 - 0.43 10.9 5.1 3.1 8.2 0.1 3.6 1 1 2 3 3 3 0 Protein of unknown function, DUF479 DUF842 PF05811.11 001171409.1_37923001_1 - 0.73 9.5 4.8 2.9 7.6 0.3 3.1 2 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Phage_Mu_Gam PF07352.10 001171409.1_37923001_1 - 0.76 9.5 4.1 2.3 8.0 0.3 2.9 3 1 0 3 3 3 0 Bacteriophage Mu Gam like protein ABC_tran_CTD PF16326.3 001171409.1_37923001_1 - 0.91 9.7 8.7 1.5 9.0 0.1 4.6 5 0 0 5 5 5 0 ABC transporter C-terminal domain BLOC1S3 PF15753.3 001171409.1_37923001_1 - 1.3 9.0 5.3 1.4 8.9 3.2 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 CorA PF01544.16 001171409.1_37923001_1 - 1.7 7.8 3.7 3.2 6.9 1.0 2.5 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF4456 PF14644.4 001171409.1_37923001_1 - 2.7 7.5 17.6 0.097 12.2 4.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4456) PilJ PF13675.4 001171409.1_37923001_1 - 4.4 7.3 14.0 9.9 6.1 1.8 4.1 2 2 3 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3538 PF12057.6 001171409.1_37923001_1 - 5.5 6.6 9.4 2.9 7.5 2.0 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3538) DUF2203 PF09969.7 001171409.1_37923001_1 - 5.7 7.6 8.4 97 3.6 3.7 3.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Homeobox PF00046.27 001319580.1_37922001_1 - 3.7e-23 81.0 6.1 8e-23 79.9 6.1 1.6 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.15 001319580.1_37922001_1 - 1.8e-07 30.6 0.2 3.5e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.9 001319580.1_37922001_1 - 0.00096 18.9 0.2 0.0027 17.5 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain LRR_8 PF13855.4 001297501.1_37925001_1 - 4.3e-22 77.5 36.1 2.3e-09 36.7 5.6 5.8 4 1 1 5 5 5 5 Leucine rich repeat TIR PF01582.18 001297501.1_37925001_1 - 1.8e-18 66.8 0.0 3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001297501.1_37925001_1 - 7.2e-11 42.0 45.9 0.00066 19.9 6.8 8.4 5 2 5 10 10 10 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001297501.1_37925001_1 - 7.4e-08 32.5 0.0 2.1e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.4 001297501.1_37925001_1 - 0.0027 17.1 15.8 0.68 9.3 2.1 3.7 2 1 0 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.31 001297501.1_37925001_1 - 0.0062 16.7 33.1 5.6 7.7 0.8 10.9 8 4 1 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.4 001297501.1_37925001_1 - 0.82 9.8 27.9 10 6.3 0.1 10.1 12 0 0 12 12 12 0 Leucine Rich repeat Neur_chan_LBD PF02931.21 001319574.1_37923001_1 - 6.6e-51 172.7 0.0 8.5e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001319574.1_37923001_1 - 1.3e-39 136.5 2.4 5.4e-31 108.3 5.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Globin PF00042.20 001171416.1_37921001_1 - 5.3e-25 88.0 0.0 8.5e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Globin Acetyltransf_1 PF00583.23 001171367.1_37922001_1 - 1.2e-15 57.6 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.5 001171367.1_37922001_1 - 9.5e-11 41.6 0.1 1.7e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 001171367.1_37922001_1 - 1.2e-08 35.1 0.0 2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.8 001171367.1_37922001_1 - 8.4e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.5 001171367.1_37922001_1 - 0.00071 19.5 0.2 0.0019 18.1 0.1 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.4 001171367.1_37922001_1 - 0.0035 17.2 0.1 0.0059 16.5 0.1 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.3 001171367.1_37922001_1 - 0.0051 16.2 0.1 0.0051 16.2 0.1 1.5 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_3 PF13302.5 001171367.1_37922001_1 - 0.0093 16.5 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Serpin PF00079.18 001171081.1_37923001_3 - 1.9e-117 392.6 0.5 2.4e-117 392.3 0.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Filamin PF00630.17 001171371.1_37929001_1 - 0 1284.6 55.0 6.8e-19 68.5 0.0 24.2 24 0 0 24 24 24 24 Filamin/ABP280 repeat CH PF00307.29 001171371.1_37929001_1 - 1.7e-39 134.2 0.6 4.8e-21 74.9 0.8 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.11 001171371.1_37929001_1 - 1e-15 57.3 17.4 0.36 10.7 0.0 12.7 14 0 0 14 14 14 3 Y_Y_Y domain DUF5060 PF16586.3 001171371.1_37929001_1 - 1.6e-14 53.8 0.5 3.8 7.8 0.0 14.2 18 0 0 18 18 17 1 Domain of unknown function (DUF5060) Big_3_5 PF16640.3 001171371.1_37929001_1 - 2.3e-11 43.6 54.8 0.52 10.4 0.1 16.8 18 0 0 18 18 18 5 Bacterial Ig-like domain (group 3) YtkA PF13115.4 001171371.1_37929001_1 - 2e-07 31.4 10.1 2.6 8.6 0.1 11.4 14 0 0 14 14 13 1 YtkA-like PapC_N PF13954.4 001171371.1_37929001_1 - 0.00011 22.0 0.0 2.2 8.1 0.0 6.4 5 1 1 6 6 6 1 PapC N-terminal domain EMP24_GP25L PF01105.22 001171371.1_37929001_1 - 0.00048 20.0 5.3 3 7.6 0.1 7.8 10 0 0 10 10 10 1 emp24/gp25L/p24 family/GOLD Invasin_D3 PF09134.8 001171371.1_37929001_1 - 0.0038 16.8 6.4 9.3 5.9 0.0 7.8 10 0 0 10 10 10 1 Invasin, domain 3 CBM60 PF16841.3 001171371.1_37929001_1 - 0.011 16.0 2.2 6.1 7.2 0.1 5.6 5 0 0 5 5 5 0 Ca-dependent carbohydrate-binding module xylan-binding CAMSAP_CH PF11971.6 001171371.1_37929001_1 - 0.03 14.0 0.1 2.1 8.1 0.1 2.6 2 0 0 2 2 2 0 CAMSAP CH domain Big_3 PF07523.10 001171371.1_37929001_1 - 0.094 12.9 22.8 15 5.9 0.2 12.0 11 1 1 12 12 12 0 Bacterial Ig-like domain (group 3) DUF3859 PF12975.5 001171371.1_37929001_1 - 0.1 12.5 0.9 1.1e+02 2.7 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF3859) CH_2 PF06294.9 001171371.1_37929001_1 - 0.15 12.1 0.4 3.2 7.8 0.2 2.2 2 0 0 2 2 2 0 CH-like domain in sperm protein Rib PF08428.8 001171371.1_37929001_1 - 1.3 9.0 13.4 3.5 7.5 1.4 5.7 5 0 0 5 5 5 0 Rib/alpha-like repeat Ig_3 PF13927.4 001171365.1_37928001_1 - 3.1e-74 245.5 0.3 1e-13 51.5 0.0 7.0 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.14 001171365.1_37928001_1 - 7.6e-70 230.9 0.0 1.3e-12 47.5 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.19 001171365.1_37928001_1 - 1.4e-65 217.5 15.9 3e-15 56.2 0.2 6.1 6 0 0 6 6 6 5 Fibronectin type III domain Ig_2 PF13895.4 001171365.1_37928001_1 - 7.9e-46 154.2 0.1 4.1e-07 30.1 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.23 001171365.1_37928001_1 - 8.4e-42 141.1 0.1 6.3e-07 29.3 0.0 7.3 7 0 0 7 7 7 6 Immunoglobulin domain Bravo_FIGEY PF13882.4 001171365.1_37928001_1 - 2.9e-28 98.9 6.2 5.9e-28 97.9 6.2 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.15 001171365.1_37928001_1 - 6.6e-18 64.7 11.2 0.0028 17.6 0.1 10.4 8 3 1 9 9 9 4 Immunoglobulin V-set domain C2-set_2 PF08205.10 001171365.1_37928001_1 - 7.9e-12 45.0 0.3 0.43 10.5 0.0 5.8 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001171365.1_37928001_1 - 1e-08 35.3 0.0 0.051 13.9 0.0 6.2 7 1 0 7 7 7 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.3 001171365.1_37928001_1 - 6.7e-05 22.7 0.1 0.37 10.7 0.0 4.7 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain BiPBP_C PF06832.10 001171365.1_37928001_1 - 0.00033 20.5 0.3 0.71 9.8 0.0 4.6 5 0 0 5 5 5 1 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.3 001171365.1_37928001_1 - 0.015 15.5 0.0 16 5.8 0.0 4.9 6 0 0 6 6 6 0 T-cell surface glycoprotein CD3 delta chain Guanylate_kin PF00625.19 001171384.1_37923001_1 - 9.2e-66 220.9 0.2 1.5e-65 220.1 0.2 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.22 001171384.1_37923001_1 - 5e-20 71.5 0.9 1.3e-19 70.2 0.9 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.15 001171384.1_37923001_1 - 5.5e-10 38.6 0.0 1.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001171384.1_37923001_1 - 7e-08 31.8 1.6 3.3e-07 29.7 1.6 2.1 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.4 001171384.1_37923001_1 - 4.2e-05 23.6 0.4 0.00014 22.0 0.1 1.9 2 0 0 2 2 2 1 PDZ domain SH3_9 PF14604.4 001171384.1_37923001_1 - 0.00024 20.7 0.0 0.00056 19.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF258 PF03193.14 001171384.1_37923001_1 - 0.0011 18.8 0.0 0.0071 16.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001171384.1_37923001_1 - 0.014 15.4 0.0 0.041 13.8 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.4 001171384.1_37923001_1 - 0.043 13.9 0.0 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain GDI PF00996.16 001171378.1_37923001_1 - 6.9e-243 805.7 0.1 8.1e-243 805.4 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.22 001171378.1_37923001_1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase G6PD_C PF02781.14 001171382.1_37924001_1 - 1.5e-118 395.1 0.0 2.5e-118 394.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.20 001171382.1_37924001_1 - 1e-60 205.2 0.0 5.1e-60 203.0 0.0 2.0 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Iso_dh PF00180.18 001171363.1_37923001_1 - 1.8e-72 244.3 0.8 2.3e-72 243.9 0.8 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Prefoldin PF02996.15 001171386.1_37922001_1 - 1.2e-37 128.3 0.8 2e-37 127.6 0.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.18 001171386.1_37922001_1 - 0.00029 20.6 4.9 0.019 14.8 0.0 2.5 2 1 0 2 2 2 2 Prefoldin subunit F5_F8_type_C PF00754.23 001171271.1_37929001_1 - 5.5e-54 181.5 0.5 1.2e-26 93.2 0.1 3.4 3 0 0 3 3 3 2 F5/8 type C domain Cu-oxidase_3 PF07732.13 001171271.1_37929001_1 - 3.2e-17 62.5 0.0 3.9e-05 23.5 0.0 3.9 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.12 001171271.1_37929001_1 - 3.3e-14 52.7 11.2 7e-08 32.2 0.1 5.3 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.20 001171271.1_37929001_1 - 7.8e-10 39.0 1.4 0.00028 20.9 0.0 4.0 5 0 0 5 5 5 2 Multicopper oxidase MBD PF01429.17 001171370.1_37923001_1 - 4.1e-17 61.5 0.0 9.6e-17 60.3 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain Ras PF00071.20 001171387.1_37922001_1 - 2.3e-59 199.5 0.0 2.8e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001171387.1_37922001_1 - 1.8e-31 108.7 0.0 2.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001171387.1_37922001_1 - 4.9e-13 48.8 0.0 5.9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001171387.1_37922001_1 - 1.4e-06 28.2 0.0 1.9e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001171387.1_37922001_1 - 7.8e-05 22.0 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.14 001171387.1_37922001_1 - 0.0006 19.6 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001171387.1_37922001_1 - 0.017 14.6 0.0 0.12 11.8 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CENP-M PF11111.6 001171387.1_37922001_1 - 0.031 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_22 PF13401.4 001171387.1_37922001_1 - 0.073 13.2 0.0 0.54 10.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain ig PF00047.23 001329074.1_37922001_1 - 3e-24 84.9 3.6 7e-14 51.6 1.3 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001329074.1_37922001_1 - 3.4e-12 46.7 1.9 2.6e-05 24.6 0.3 2.6 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001329074.1_37922001_1 - 3.8e-09 36.6 1.1 7.6e-09 35.6 0.7 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.10 001329074.1_37922001_1 - 1.6e-07 31.2 0.5 4.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.14 001329074.1_37922001_1 - 8.2e-07 28.9 0.6 0.041 13.8 0.2 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.4 001329074.1_37922001_1 - 1.9e-05 24.7 2.4 0.15 12.3 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.13 001329074.1_37922001_1 - 0.0043 17.4 1.5 0.078 13.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin C1-set domain TMEM132D_C PF15706.3 001329074.1_37922001_1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term LRR_8 PF13855.4 001329073.1_37926001_1 - 1.3e-45 152.8 34.3 1.2e-12 47.2 3.9 9.8 9 1 2 11 11 11 8 Leucine rich repeat LRR_4 PF12799.5 001329073.1_37926001_1 - 3.2e-17 62.1 35.2 5.1e-06 26.6 0.5 11.1 9 5 4 13 13 13 5 Leucine Rich repeats (2 copies) TIR PF01582.18 001329073.1_37926001_1 - 3.7e-10 39.7 0.0 5.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001329073.1_37926001_1 - 3.8e-10 39.4 5.6 0.0012 18.2 0.1 4.6 5 1 1 6 6 6 2 Leucine-rich repeat TIR_2 PF13676.4 001329073.1_37926001_1 - 2.1e-08 34.3 0.0 1.3e-07 31.7 0.0 2.2 1 1 1 2 2 2 1 TIR domain LRR_5 PF13306.4 001329073.1_37926001_1 - 4e-07 29.9 0.0 0.042 13.7 0.0 4.0 5 0 0 5 5 5 2 Leucine rich repeats (6 copies) LRR_1 PF00560.31 001329073.1_37926001_1 - 0.0022 18.1 10.6 26 5.7 0.0 8.7 9 0 0 9 9 9 0 Leucine Rich Repeat DUF4516 PF14990.4 001329073.1_37926001_1 - 0.25 10.9 0.7 0.64 9.7 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) VWD PF00094.23 001329088.1_37929001_1 - 6.3e-128 422.9 7.4 8.2e-37 126.8 0.0 4.5 4 0 0 4 4 4 4 von Willebrand factor type D domain VWA PF00092.26 001329088.1_37929001_1 - 4.5e-80 267.9 0.0 2.9e-30 105.7 0.0 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain C8 PF08742.9 001329088.1_37929001_1 - 4.4e-53 177.5 60.8 2e-17 63.2 8.7 8.6 8 0 0 8 8 8 4 C8 domain VWA_N2 PF16164.3 001329088.1_37929001_1 - 1.3e-39 134.1 4.6 1.3e-39 134.1 4.6 8.8 9 0 0 9 9 9 1 VWA N-terminal TIL PF01826.15 001329088.1_37929001_1 - 1.6e-30 104.9 107.1 2.1e-12 47.0 17.9 20.4 17 5 5 22 22 22 5 Trypsin Inhibitor like cysteine rich domain VWC PF00093.16 001329088.1_37929001_1 - 5.2e-18 65.0 74.8 4.5e-09 36.4 12.8 21.7 15 5 3 18 18 18 7 von Willebrand factor type C domain Pacifastin_I PF05375.11 001329088.1_37929001_1 - 0.0006 19.3 24.8 0.00063 19.3 8.9 12.7 16 0 0 16 16 16 2 Pacifastin inhibitor (LCMII) FA_desaturase PF00487.22 001329067.1_37923001_1 - 1.4e-34 119.9 31.2 3e-34 118.9 25.6 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.26 001329067.1_37923001_1 - 9e-21 73.7 0.1 2.2e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Asp PF00026.21 001329076.1_37923001_1 - 3.3e-123 411.0 6.7 3.9e-123 410.7 6.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001329076.1_37923001_1 - 7.1e-17 62.1 1.3 2.2e-14 54.0 1.3 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001329076.1_37923001_1 - 1e-10 41.1 1.8 2e-10 40.2 1.8 1.4 1 0 0 1 1 1 1 A1 Propeptide TIR PF01582.18 001329068.1_37924001_1 - 2.8e-43 147.6 0.0 5.5e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.4 001329068.1_37924001_1 - 9.9e-15 54.5 1.6 1.4e-05 25.3 0.4 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001329068.1_37924001_1 - 1.9e-12 47.5 0.5 0.00031 21.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.14 001329068.1_37924001_1 - 4.2e-07 29.8 0.0 0.042 13.8 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain TIR_2 PF13676.4 001329068.1_37924001_1 - 4.6e-05 23.6 0.0 9.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 TIR domain Ig_5 PF16681.3 001329068.1_37924001_1 - 0.00015 22.0 0.2 0.0069 16.6 0.1 3.4 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ig PF00047.23 001329068.1_37924001_1 - 0.00021 21.3 0.1 0.52 10.4 0.0 3.9 3 1 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.3 001329068.1_37924001_1 - 0.00025 21.2 0.8 0.0082 16.3 0.2 2.6 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain DUF3568 PF12092.6 001329068.1_37924001_2 - 0.13 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) TGF_beta PF00019.18 001171487.1_37924001_1 - 3.9e-32 111.1 0.5 5.8e-32 110.6 0.5 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 001171487.1_37924001_1 - 1.3e-13 51.1 0.0 2.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide Ion_trans_2 PF07885.14 001082736.1_37924001_2 - 1.6e-37 127.2 21.7 5.4e-19 67.8 10.6 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.29 001082736.1_37924001_2 - 1.3e-06 27.7 11.7 2e-06 27.1 0.2 2.5 2 1 0 2 2 2 1 Ion transport protein DUF2390 PF09523.8 001082736.1_37924001_2 - 0.048 13.9 0.7 0.048 13.9 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) PLC-beta_C PF08703.8 001082736.1_37924001_2 - 0.086 12.7 0.3 0.086 12.7 0.3 2.4 2 0 0 2 2 2 0 PLC-beta C terminal E1-E2_ATPase PF00122.18 001082736.1_37924001_2 - 0.55 9.4 4.7 1 8.5 1.4 2.3 2 0 0 2 2 2 0 E1-E2 ATPase FGF PF00167.16 001171488.1_37921001_1 - 1.6e-42 144.5 0.0 2e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 001171488.1_37921001_1 - 4.8e-07 29.8 0.1 0.0037 17.3 0.0 1.6 1 1 1 2 2 2 2 Fascin domain Serpin PF00079.18 001171282.1_37923001_1 - 9.1e-131 436.4 0.5 1e-130 436.2 0.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sulfotransfer_1 PF00685.25 001081987.1_37922001_1 - 4.6e-85 285.2 0.8 5.3e-85 285.0 0.8 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001081987.1_37922001_1 - 6.6e-11 42.9 0.0 3.5e-09 37.2 0.0 2.3 1 1 0 2 2 2 1 Sulfotransferase family 7tm_1 PF00001.19 001082738.1_37923001_1 - 7.7e-39 133.4 15.4 7.7e-39 133.4 15.4 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Colicin_V PF02674.14 001082738.1_37923001_1 - 0.082 12.7 2.7 2.3 8.1 0.6 3.1 3 0 0 3 3 3 0 Colicin V production protein Serpin PF00079.18 001171285.1_37923001_1 - 2e-127 425.4 2.0 2.3e-127 425.2 2.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.18 001171286.1_37923001_1 - 2e-120 402.4 0.2 2.3e-120 402.2 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.18 001082741.2_37925001_3 - 8.2e-87 291.8 0.0 9.7e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pox_L3_FP4 PF03339.12 001082741.2_37925001_3 - 0.21 10.4 0.0 0.33 9.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein PAC1 PF16094.3 001171289.1_37922001_1 - 8.9e-127 422.0 3.5 1.1e-126 421.7 3.5 1.0 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 MFS_1 PF07690.14 001171293.1_37923001_1 - 9.3e-61 205.6 35.1 2e-60 204.5 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cas1_AcylT PF07779.10 001171293.1_37923001_1 - 0.11 11.2 7.3 0.042 12.6 4.5 1.7 2 0 0 2 2 2 0 10 TM Acyl Transferase domain found in Cas1p DUF3671 PF12420.6 001171293.1_37923001_1 - 0.21 11.6 1.8 1.6 8.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function Sema PF01403.17 001171295.1_37926001_1 - 1.1e-116 389.9 0.0 1.6e-116 389.5 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.23 001171295.1_37926001_1 - 0.0003 21.1 7.7 0.00073 19.9 7.7 1.7 1 0 0 1 1 1 1 Plexin repeat DUF3915 PF13054.4 001081995.1_37926001_1 - 1.2 9.0 7.4 1.8 8.4 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 001081995.1_37926001_1 - 5 5.1 16.2 6.5 4.8 16.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family TNFR_c6 PF00020.16 001081995.1_37926001_2 - 1.1e-12 48.0 45.5 1.7e-07 31.4 9.9 3.6 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region PRP38_assoc PF12871.5 001081995.1_37926001_2 - 0.0078 16.6 8.0 0.013 15.9 8.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Atrophin-1 PF03154.13 001081995.1_37926001_2 - 5.3 5.1 16.9 7.1 4.6 16.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family Death PF00531.20 001081995.1_37926001_3 - 1.1e-18 67.0 0.2 1.6e-18 66.5 0.2 1.3 1 0 0 1 1 1 1 Death domain DUF3915 PF13054.4 001081995.1_37926001_3 - 0.004 17.0 2.6 0.009 15.9 2.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Atrophin-1 PF03154.13 001081995.1_37926001_3 - 0.0057 14.9 6.4 0.0077 14.5 6.4 1.1 1 0 0 1 1 1 1 Atrophin-1 family Romo1 PF10247.7 001171498.1_37921001_1 - 5.3e-26 90.6 20.9 6.2e-26 90.4 20.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.17 001171498.1_37921001_1 - 0.001 19.3 8.3 0.0011 19.1 8.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TCRP1 PF14944.4 001171498.1_37921001_1 - 0.36 10.6 1.2 0.33 10.7 0.2 1.4 1 1 1 2 2 2 0 Tongue Cancer Chemotherapy Resistant Protein 1 SIR2_2 PF13289.4 001171498.1_37921001_3 - 0.17 11.9 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 SIR2-like domain SCNM1_acidic PF15805.3 001171298.1_37922001_1 - 1.9e-25 88.1 0.7 3.6e-25 87.3 0.7 1.4 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 zf-SCNM1 PF15803.3 001171298.1_37922001_1 - 1.6e-15 56.2 1.5 2.8e-15 55.5 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of sodium channel modifier 1 zf-C4 PF00105.16 001082000.1_37923001_1 - 5.2e-28 97.2 17.4 1e-27 96.2 17.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001082000.1_37923001_1 - 6.3e-16 58.5 0.5 1.8e-15 56.9 0.1 1.9 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Tropomodulin PF03250.12 001171299.1_37923001_1 - 1.7e-58 196.5 5.1 1.7e-58 196.5 5.1 1.6 2 0 0 2 2 2 1 Tropomodulin TBPIP PF07106.11 001171299.1_37923001_1 - 0.24 11.0 2.4 0.37 10.4 0.3 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-C2H2_4 PF13894.4 001171302.1_37928001_1 - 4e-18 64.4 96.8 0.016 15.8 2.2 14.4 14 0 0 14 14 14 12 C2H2-type zinc finger zf-C2H2_11 PF16622.3 001171302.1_37928001_1 - 4.3e-18 64.6 10.6 8.3e-15 54.1 0.6 9.0 12 0 0 12 12 12 4 zinc-finger C2H2-type zf-C2H2 PF00096.24 001171302.1_37928001_1 - 6.7e-15 54.5 98.2 0.0085 16.4 1.9 14.3 14 0 0 14 14 14 11 Zinc finger, C2H2 type zf-met PF12874.5 001171302.1_37928001_1 - 3.4e-05 23.9 47.8 0.01 16.0 1.3 10.1 11 0 0 11 11 11 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.4 001171302.1_37928001_1 - 0.029 14.7 0.5 0.029 14.7 0.5 12.8 16 0 0 16 16 16 0 Zinc-finger double domain zf-C2H2_jaz PF12171.6 001171302.1_37928001_1 - 0.034 14.3 31.0 0.19 11.9 0.1 9.1 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding Proteasome PF00227.24 001171305.1_37922001_1 - 4.4e-33 114.2 0.0 5.1e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Myosin_tail_1 PF01576.17 001171307.1_37928001_1 - 6e-35 120.3 197.6 2.5e-34 118.2 83.2 3.1 1 1 2 3 3 3 2 Myosin tail DUF1664 PF07889.10 001171307.1_37928001_1 - 0.0011 18.8 7.6 0.0011 18.8 7.6 9.7 2 1 5 10 10 10 6 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.10 001171307.1_37928001_1 - 0.0032 16.8 3.7 0.0032 16.8 3.7 6.6 3 3 5 8 8 8 4 Reovirus sigma C capsid protein ADIP PF11559.6 001171307.1_37928001_1 - 0.0052 16.7 15.0 0.0052 16.7 15.0 10.4 3 2 6 10 10 10 2 Afadin- and alpha -actinin-Binding DUF4719 PF15843.3 001171307.1_37928001_1 - 0.65 9.9 2.9 1.9 8.4 2.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) zf-H2C2_2 PF13465.4 001171309.1_37926001_1 - 3.6e-42 140.8 46.7 1.7e-08 34.4 0.2 7.9 7 0 0 7 7 7 6 Zinc-finger double domain SCAN PF02023.15 001171309.1_37926001_1 - 1.1e-41 140.4 1.8 1.1e-41 140.4 1.8 2.2 2 0 0 2 2 1 1 SCAN domain Myb_DNA-bind_4 PF13837.4 001171309.1_37926001_1 - 4.2e-41 139.1 0.1 3e-19 69.1 0.0 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain zf-C2H2 PF00096.24 001171309.1_37926001_1 - 3.1e-37 124.8 48.6 2e-06 27.8 0.5 6.9 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001171309.1_37926001_1 - 1.7e-18 65.6 47.8 0.0061 17.2 1.8 7.8 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_11 PF16622.3 001171309.1_37926001_1 - 6.8e-08 32.0 27.5 0.0033 17.0 1.2 6.4 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.4 001171309.1_37926001_1 - 1.1e-07 31.5 35.4 0.017 15.0 2.5 6.7 6 0 0 6 6 6 4 C2H2-type zinc finger MADF_DNA_bdg PF10545.7 001171309.1_37926001_1 - 1.2e-06 28.6 0.3 0.051 13.8 0.1 3.0 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-C2H2_jaz PF12171.6 001171309.1_37926001_1 - 1e-05 25.6 23.0 0.23 11.7 0.5 6.4 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.3 001171309.1_37926001_1 - 5.8e-05 23.6 16.6 0.026 15.1 1.8 4.1 2 1 1 3 3 3 3 zinc-ribbon family zf-LYAR PF08790.9 001171309.1_37926001_1 - 0.00087 19.0 30.6 0.25 11.2 0.4 7.1 7 0 0 7 7 7 3 LYAR-type C2HC zinc finger Myb_DNA-bind_3 PF12776.5 001171309.1_37926001_1 - 0.0054 17.4 1.2 1.9 9.2 0.1 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.4 001171309.1_37926001_1 - 0.0067 16.5 0.2 2.6 8.2 0.0 3.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain OSTMP1 PF09777.7 001171309.1_37926001_1 - 0.0093 15.3 10.7 1.3 8.2 3.3 3.5 3 1 0 3 3 3 1 Osteopetrosis-associated transmembrane protein 1 precursor Zn-ribbon_8 PF09723.8 001171309.1_37926001_1 - 0.022 14.8 41.4 0.037 14.0 3.1 7.0 5 1 3 9 9 7 0 Zinc ribbon domain Myb_DNA-binding PF00249.29 001171309.1_37926001_1 - 0.025 14.6 0.8 9.8 6.3 0.0 3.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain DNA_RNApol_7kD PF03604.11 001171309.1_37926001_1 - 0.044 13.3 18.8 4.1 7.0 0.1 6.2 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit XPA_N PF01286.16 001171309.1_37926001_1 - 0.044 13.7 30.9 1.9 8.4 0.4 6.4 6 0 0 6 6 6 0 XPA protein N-terminal HypA PF01155.17 001171309.1_37926001_1 - 0.092 12.6 15.1 3.4 7.6 0.8 3.9 2 1 2 4 4 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.5 001171309.1_37926001_1 - 0.12 12.2 28.8 0.061 13.2 2.2 4.4 3 1 2 5 5 4 0 Double zinc ribbon zf-trcl PF13451.4 001171309.1_37926001_1 - 0.16 11.7 20.3 17 5.3 0.1 6.7 6 0 0 6 6 6 0 Probable zinc-ribbon domain DUF3268 PF11672.6 001171309.1_37926001_1 - 0.29 11.3 12.4 1.5 9.0 0.6 3.7 3 0 0 3 3 3 0 zinc-finger-containing domain zf-met PF12874.5 001171309.1_37926001_1 - 2.2 8.7 42.5 0.098 12.9 2.3 6.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type CpXC PF14353.4 001171309.1_37926001_1 - 3.4 7.6 15.1 20 5.1 0.4 5.4 3 2 3 6 6 5 0 CpXC protein ADK_lid PF05191.12 001171309.1_37926001_1 - 3.5 7.6 16.1 20 5.2 4.9 4.5 2 2 1 3 3 3 0 Adenylate kinase, active site lid YhfH PF14149.4 001171309.1_37926001_1 - 4 7.4 21.2 26 4.8 0.2 6.5 6 0 0 6 6 6 0 YhfH-like protein Lactamase_B_6 PF16661.3 001171311.1_37929001_1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain ATP-gua_Ptrans PF00217.17 001171313.1_37923001_1 - 9.5e-96 320.0 0.0 1.1e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.13 001171313.1_37923001_1 - 2e-31 108.1 0.0 3.2e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Occludin_ELL PF07303.11 001171316.1_37923001_1 - 1e-30 106.3 7.1 1.9e-30 105.4 7.1 1.5 1 0 0 1 1 1 1 Occludin homology domain ELL PF10390.7 001171316.1_37923001_1 - 4e-10 39.5 0.0 1.3e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL Glyco_tranf_2_3 PF13641.4 001082010.1_37924001_1 - 5.2e-20 72.2 0.1 1.5e-15 57.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.13 001082010.1_37924001_1 - 6.7e-19 67.8 5.4 9.8e-15 54.0 3.0 3.3 2 1 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.24 001082010.1_37924001_1 - 1.7e-09 37.6 0.0 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.4 001082010.1_37924001_1 - 2.3e-07 30.8 13.8 1.1e-06 28.6 13.8 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.4 001082010.1_37924001_1 - 0.0019 17.6 0.0 0.0048 16.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Phage_holin_8 PF16931.3 001082010.1_37924001_1 - 0.059 13.2 0.4 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Putative phage holin DUF3742 PF12553.6 001082010.1_37924001_1 - 0.86 9.6 4.1 2.1 8.4 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) WD40 PF00400.30 001171318.1_37924001_1 - 8.9e-06 26.2 9.1 0.23 12.3 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat OSTMP1 PF09777.7 001171322.1_37922001_1 - 1.4e-85 286.3 13.6 1.6e-85 286.1 13.6 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.4 001171322.1_37922001_1 - 0.0048 16.6 0.1 0.01 15.5 0.1 1.5 1 1 0 1 1 1 1 CECR6/TMEM121 family Crust_neurohorm PF01147.15 001171322.1_37922001_1 - 0.13 12.0 4.0 0.28 10.9 0.1 2.8 2 1 1 3 3 3 0 Crustacean CHH/MIH/GIH neurohormone family zf-AD PF07776.13 001171322.1_37922001_1 - 3.1 8.0 9.4 0.76 9.9 3.3 2.5 1 1 2 3 3 3 0 Zinc-finger associated domain (zf-AD) PX PF00787.22 001171324.1_37921001_1 - 2.2e-28 98.4 0.0 2.7e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 PX domain STAG PF08514.9 001171326.1_37928001_1 - 5.1e-38 129.3 0.2 3.1e-37 126.8 0.2 2.5 1 0 0 1 1 1 1 STAG domain Cnd3 PF12719.5 001171326.1_37928001_1 - 0.01 15.0 0.3 0.01 15.0 0.3 2.2 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain AdoHcyase_NAD PF00670.19 001171326.1_37928001_1 - 0.038 13.9 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TOM6p PF15184.4 001171253.1_37921001_1 - 6.5e-46 153.9 0.5 7.1e-46 153.8 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit TOM6 homolog Tom6 PF17112.3 001171253.1_37921001_1 - 0.0081 15.5 0.2 0.017 14.5 0.2 1.4 1 1 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal SBF PF01758.14 001082768.1_37923001_3 - 1.7e-44 151.7 16.4 1.7e-44 151.7 16.4 2.8 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.4 001082768.1_37923001_3 - 0.00026 20.3 21.8 0.00039 19.7 21.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) GAPT PF11770.6 001082768.1_37923001_3 - 0.013 15.3 0.8 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Mem_trans PF03547.16 001082768.1_37923001_3 - 0.056 11.7 23.8 0.37 9.0 2.5 3.2 1 1 2 3 3 3 0 Membrane transport protein MOEP19 PF16005.3 001171255.1_37921001_1 - 2.2e-38 130.0 0.2 2.7e-38 129.7 0.2 1.1 1 0 0 1 1 1 1 KH-like RNA-binding domain KH_1 PF00013.27 001171255.1_37921001_1 - 0.21 11.3 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 KH domain Trypsin PF00089.24 001082769.1_37926001_3 - 4.8e-64 216.1 0.0 7.9e-64 215.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin Kringle PF00051.16 001082769.1_37926001_3 - 4.3e-45 151.8 22.1 2e-25 88.8 1.7 2.8 3 0 0 3 3 3 2 Kringle domain fn1 PF00039.16 001082769.1_37926001_3 - 2e-08 34.1 3.1 5.7e-08 32.7 3.1 1.8 1 0 0 1 1 1 1 Fibronectin type I domain EGF PF00008.25 001082769.1_37926001_3 - 6.2e-07 29.5 4.5 6.2e-07 29.5 4.5 3.2 2 0 0 2 2 2 1 EGF-like domain DUF1986 PF09342.9 001082769.1_37926001_3 - 0.0025 18.0 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) hEGF PF12661.5 001082769.1_37926001_3 - 0.0054 17.2 3.5 0.0054 17.2 3.5 3.6 2 0 0 2 2 2 1 Human growth factor-like EGF cEGF PF12662.5 001082769.1_37926001_3 - 5.7 6.8 7.4 0.52 10.2 0.5 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like Utp11 PF03998.11 001171256.1_37921001_1 - 0.031 14.1 3.8 0.034 13.9 3.8 1.1 1 0 0 1 1 1 0 Utp11 protein DUF4758 PF15950.3 001171256.1_37921001_1 - 0.061 13.5 0.2 0.085 13.0 0.2 1.2 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein SPT6_acidic PF14632.4 001171256.1_37921001_1 - 0.42 11.1 8.4 0.55 10.7 7.7 1.5 1 1 0 1 1 1 0 Acidic N-terminal SPT6 Globin PF00042.20 001171414.1_37921001_1 - 4.4e-28 97.9 0.0 5.8e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Globin p450 PF00067.20 001168395.1_37924001_1 - 4.4e-135 450.9 0.0 5e-135 450.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.20 001168397.1_37924001_1 - 1.4e-136 455.8 0.0 1.6e-136 455.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kringle PF00051.16 001168707.1_37925001_1 - 3.9e-112 366.6 44.8 6.9e-29 99.9 7.7 4.4 4 0 0 4 4 4 4 Kringle domain Trypsin PF00089.24 001168707.1_37925001_1 - 7.1e-51 173.0 0.1 1.2e-50 172.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.24 001168707.1_37925001_1 - 1.8e-09 37.3 0.4 5.8e-09 35.7 0.4 1.9 1 0 0 1 1 1 1 PAN domain DUF1986 PF09342.9 001168707.1_37925001_1 - 0.0097 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CWC25 PF12542.6 001168707.1_37925001_1 - 0.19 12.4 0.2 0.36 11.6 0.2 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor Ribosomal_L32e PF01655.16 001171505.1_37921001_1 - 2.6e-58 194.9 2.3 3e-58 194.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 HNH_5 PF14279.4 001171505.1_37921001_3 - 0.084 12.6 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 HNH endonuclease SIR2 PF02146.15 001177331.1_37923001_3 - 2.8e-53 180.3 0.0 3.7e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Prok-RING_4 PF14447.4 001177331.1_37923001_3 - 0.1 12.4 3.0 0.082 12.6 0.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Lipase PF00151.17 001177330.1_37928001_2 - 8.2e-129 429.6 0.0 1.2e-128 429.1 0.0 1.2 1 0 0 1 1 1 1 Lipase PLAT PF01477.21 001177330.1_37928001_2 - 3.4e-26 92.0 0.6 5.5e-26 91.3 0.6 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.5 001177330.1_37928001_2 - 0.00022 21.8 0.3 0.00044 20.8 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001177330.1_37928001_2 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1815 PF08844.8 001177330.1_37928001_2 - 0.15 11.9 0.4 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) RRM_1 PF00076.20 001185148.2_37925001_1 - 1.2e-60 201.1 0.1 1.6e-19 69.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001185148.2_37925001_1 - 8.8e-10 38.1 0.0 0.0013 18.1 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.10 001185148.2_37925001_1 - 0.00027 21.0 0.0 0.2 11.8 0.0 2.7 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_3 PF08777.9 001185148.2_37925001_1 - 0.0017 18.2 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.3 001185148.2_37925001_1 - 0.004 16.8 0.0 1.4 8.7 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.3 001185148.2_37925001_1 - 0.042 13.8 0.0 2.1 8.4 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif Peptidase_C1 PF00112.21 001082786.1_37924001_1 - 4.5e-49 167.4 6.5 8.8e-49 166.4 6.5 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Somatomedin_B PF01033.15 001082786.1_37924001_1 - 6.9e-07 29.4 21.8 6.9e-07 29.4 21.8 3.0 4 0 0 4 4 4 1 Somatomedin B domain Peptidase_C1_2 PF03051.13 001082786.1_37924001_1 - 0.0063 15.2 0.3 0.011 14.4 0.3 1.3 1 0 0 1 1 1 1 Peptidase C1-like family Propeptide_C1 PF08127.11 001082786.1_37924001_1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide E1_DerP2_DerF2 PF02221.13 001082787.2_37922001_3 - 6e-14 52.5 0.2 7.2e-14 52.2 0.2 1.1 1 0 0 1 1 1 1 ML domain Myosin_head PF00063.19 001195656.1_37929001_2 - 1.3e-286 952.1 2.9 1.3e-286 952.1 2.9 3.1 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.17 001195656.1_37929001_2 - 7e-162 540.6 271.0 8.5e-162 540.3 271.0 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.17 001195656.1_37929001_2 - 6.4e-12 44.9 2.1 1.9e-11 43.4 2.1 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.10 001195656.1_37929001_2 - 0.00012 21.5 80.6 0.002 17.5 3.8 9.1 1 1 9 10 10 10 6 Reovirus sigma C capsid protein BBP1_C PF15272.4 001195656.1_37929001_2 - 0.0032 17.2 22.0 0.0032 17.2 22.0 9.5 1 1 6 9 9 9 1 Spindle pole body component BBP1, C-terminal Syntaxin-6_N PF09177.9 001195656.1_37929001_2 - 0.0063 16.9 6.5 0.0063 16.9 6.5 13.3 4 3 5 10 10 10 2 Syntaxin 6, N-terminal IQ PF00612.25 001195656.1_37929001_2 - 0.011 15.4 1.0 0.074 12.8 0.1 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.4 001195656.1_37929001_2 - 0.073 13.2 0.0 0.073 13.2 0.0 6.2 4 2 1 5 5 5 0 AAA domain Syja_N PF02383.16 001082046.1_37925001_1 - 3.8e-07 29.6 0.3 1.4e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 SacI homology domain Mt_ATP-synt_D PF05873.10 001082046.1_37925001_1 - 0.00016 21.4 6.5 0.00016 21.4 6.5 4.6 3 2 2 5 5 5 1 ATP synthase D chain, mitochondrial (ATP5H) ADIP PF11559.6 001082046.1_37925001_1 - 0.0058 16.6 7.1 0.0058 16.6 7.1 5.9 2 2 5 7 7 7 1 Afadin- and alpha -actinin-Binding Invasin_D3 PF09134.8 001082046.1_37925001_1 - 0.054 13.1 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 Invasin, domain 3 TMF_TATA_bd PF12325.6 001082046.1_37925001_1 - 0.062 13.4 80.6 0.68 10.0 13.0 6.7 2 2 4 6 6 6 0 TATA element modulatory factor 1 TATA binding GAS PF13851.4 001082046.1_37925001_1 - 0.16 11.2 91.8 0.16 11.2 8.8 4.9 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding FPP PF05911.9 001082046.1_37925001_1 - 1.1 7.3 79.0 0.015 13.5 12.3 3.6 2 1 2 4 4 4 0 Filament-like plant protein, long coiled-coil Syja_N PF02383.16 001082046.1_37925001_3 - 5.7e-24 84.8 0.3 7.5e-24 84.5 0.3 1.1 1 0 0 1 1 1 1 SacI homology domain Trypsin PF00089.24 001082792.1_37925001_1 - 5.7e-72 242.0 0.7 8.8e-72 241.4 0.7 1.3 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.24 001082792.1_37925001_1 - 1.1e-30 105.3 28.1 2.5e-08 33.6 1.5 4.7 5 0 0 5 5 5 4 PAN domain PAN_4 PF14295.4 001082792.1_37925001_1 - 3.9e-20 71.3 13.9 2.1e-05 24.2 0.2 5.0 5 0 0 5 5 5 4 PAN domain Trypsin_2 PF13365.4 001082792.1_37925001_1 - 3.7e-05 24.5 0.0 0.0001 23.0 0.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001082792.1_37925001_1 - 0.00039 20.7 0.0 0.00084 19.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) MANEC PF07502.12 001082792.1_37925001_1 - 0.00048 20.2 18.1 0.11 12.6 0.4 4.5 4 0 0 4 4 4 2 MANEC domain PAN_2 PF08276.9 001082792.1_37925001_1 - 0.0053 16.6 18.6 0.049 13.5 2.2 4.5 4 0 0 4 4 4 2 PAN-like domain Glyco_transf_29 PF00777.16 001082051.1_37924001_3 - 2.3e-62 210.7 0.0 3e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) MHC_I_3 PF16497.3 001089311.1_37923001_1 - 1.2e-77 259.8 0.0 1.5e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.13 001089311.1_37923001_1 - 6.6e-09 36.0 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001089311.1_37923001_1 - 6.4e-05 22.5 0.0 9.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 zf-C2H2 PF00096.24 001082053.1_37922001_1 - 5.7e-18 64.1 20.9 9.8e-07 28.8 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001082053.1_37922001_1 - 1e-12 47.7 7.5 9.7e-08 32.0 1.1 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001082053.1_37922001_1 - 2e-10 40.5 18.8 0.00033 21.1 1.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.3 001082053.1_37922001_1 - 0.00019 21.9 4.5 0.06 13.8 0.1 2.7 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-met PF12874.5 001082053.1_37922001_1 - 0.0003 20.9 10.7 0.00091 19.4 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.3 001082053.1_37922001_1 - 0.0039 17.2 4.4 0.52 10.3 0.1 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_6 PF13912.4 001082053.1_37922001_1 - 0.018 14.8 1.0 0.018 14.8 1.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger IBR PF01485.19 001082053.1_37922001_1 - 0.46 10.6 6.7 2.6 8.2 6.7 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.6 001082053.1_37922001_1 - 4.1 7.7 9.2 2.8 8.2 0.1 3.2 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Sugar_tr PF00083.22 001089313.1_37925001_1 - 2.5e-153 511.0 15.6 3e-153 510.8 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001089313.1_37925001_1 - 3.6e-16 58.9 41.4 1e-14 54.1 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.3 001089313.1_37925001_1 - 0.02 14.5 0.2 0.079 12.6 0.2 2.0 1 0 0 1 1 1 0 Bacteriophage holin family HP1 UMPH-1 PF05822.10 001089315.1_37923001_3 - 7.9e-117 389.0 2.4 9.6e-117 388.7 2.4 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.5 001089315.1_37923001_3 - 0.00017 21.9 0.2 0.00038 20.8 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zf-ANAPC11 PF12861.5 001089315.1_37923001_3 - 0.0087 16.0 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CIDE-N PF02017.13 001089315.1_37923001_3 - 0.046 13.6 0.4 0.77 9.7 0.0 2.9 3 0 0 3 3 3 0 CIDE-N domain NIF PF03031.16 001089315.1_37923001_3 - 0.05 13.2 0.1 2.1 8.0 0.0 2.4 1 1 0 2 2 2 0 NLI interacting factor-like phosphatase ACT_7 PF13840.4 001089315.1_37923001_3 - 0.097 12.4 0.1 3 7.6 0.1 2.6 2 0 0 2 2 2 0 ACT domain PMP22_Claudin PF00822.18 001089316.1_37922001_1 - 8.7e-51 172.0 9.7 9.9e-51 171.8 9.7 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001089316.1_37922001_1 - 1.6e-11 44.2 7.6 3.3e-10 39.9 7.6 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.10 001089316.1_37922001_1 - 0.0025 17.4 6.3 0.027 14.0 5.9 2.2 1 1 0 1 1 1 1 SUR7/PalI family CD20 PF04103.13 001089316.1_37922001_1 - 0.012 15.6 1.1 0.012 15.6 1.1 2.9 2 1 1 3 3 3 0 CD20-like family ThrE PF06738.10 001089316.1_37922001_1 - 0.015 14.5 0.7 0.015 14.5 0.7 2.6 2 1 0 3 3 3 0 Putative threonine/serine exporter DUF898 PF05987.11 001089316.1_37922001_1 - 0.048 12.6 5.2 0.0091 14.9 1.3 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) YccF PF03733.11 001089316.1_37922001_1 - 0.23 12.0 0.6 0.23 12.0 0.6 4.1 5 0 0 5 5 5 0 Inner membrane component domain DUF4064 PF13273.4 001089316.1_37922001_1 - 0.25 11.6 15.1 2.5 8.4 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF2613 PF11021.6 001089316.1_37922001_1 - 1 9.4 4.1 1 9.4 2.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) G0-G1_switch_2 PF15103.4 001089316.1_37922001_1 - 9.1 6.6 5.7 6.3 7.1 0.1 2.6 2 1 1 3 3 3 0 G0/G1 switch protein 2 Peptidase_C2 PF00648.19 001082059.1_37925001_3 - 5.2e-137 455.6 1.1 7.9e-137 455.0 1.1 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.20 001082059.1_37925001_3 - 1.2e-56 190.8 0.0 2.5e-56 189.8 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.30 001082059.1_37925001_3 - 4.3e-18 63.3 0.8 1.8e-05 23.9 0.0 4.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.4 001082059.1_37925001_3 - 6e-15 53.7 2.6 0.00013 21.5 0.0 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.4 001082059.1_37925001_3 - 1.5e-10 40.6 5.0 8.7e-07 28.5 0.2 4.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.4 001082059.1_37925001_3 - 6.9e-10 37.9 2.0 0.07 12.6 0.8 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.4 001082059.1_37925001_3 - 3.3e-09 36.9 7.8 0.00028 21.2 0.5 4.0 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.5 001082059.1_37925001_3 - 0.37 10.6 1.7 22 4.9 0.2 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand 7tm_1 PF00001.19 001082062.1_37924001_1 - 5.5e-79 265.0 6.5 7.6e-79 264.6 6.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001082062.1_37924001_1 - 4.9e-15 55.5 6.4 8.3e-15 54.7 6.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001082062.1_37924001_1 - 3.5e-07 30.1 5.3 1.1e-05 25.2 3.9 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001082062.1_37924001_1 - 1.3e-05 24.6 7.2 2.4e-05 23.7 7.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.7 001082062.1_37924001_1 - 0.0015 17.8 0.9 0.0015 17.8 0.9 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv Shisa PF13908.4 001082062.1_37924001_1 - 0.016 15.3 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Lectin_C PF00059.19 001082352.1_37924001_2 - 5.3e-23 81.7 2.8 1.1e-22 80.7 2.8 1.5 1 0 0 1 1 1 1 Lectin C-type domain Sushi PF00084.18 001082352.1_37924001_2 - 1.2e-12 48.1 15.4 1.4e-06 28.7 1.8 3.3 2 1 1 3 3 3 2 Sushi repeat (SCR repeat) EGF PF00008.25 001082352.1_37924001_2 - 8.8e-06 25.8 9.9 5e-05 23.4 9.9 2.4 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.5 001082352.1_37924001_2 - 0.00052 20.5 6.0 0.0041 17.6 6.0 2.8 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.11 001082352.1_37924001_2 - 0.00097 19.3 11.7 0.0051 17.0 11.7 2.4 1 0 0 1 1 1 1 EGF-like domain EGF_3 PF12947.5 001082352.1_37924001_2 - 0.0069 16.4 5.6 0.044 13.8 5.6 2.5 1 0 0 1 1 1 1 EGF domain Integrin_alpha2 PF08441.10 001082065.1_37927001_3 - 7.3e-105 351.4 0.0 8.6e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 001082065.1_37927001_3 - 8.9e-20 70.4 22.4 6.2e-09 35.7 0.1 5.1 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.4 001082065.1_37927001_3 - 1.7e-11 44.4 6.5 4.9e-05 23.7 0.4 4.0 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001082065.1_37927001_3 - 0.00033 20.3 0.1 0.00076 19.2 0.1 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.3 001082065.1_37927001_3 - 0.28 10.6 0.4 0.41 10.0 0.4 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Integrin_beta PF00362.16 001082066.1_37928001_1 - 1e-112 375.7 0.0 1.4e-112 375.3 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.9 001082066.1_37928001_1 - 6.2e-22 76.9 1.3 6.2e-22 76.9 1.3 1.7 2 0 0 2 2 2 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.10 001082066.1_37928001_1 - 1.3e-21 76.7 11.4 1.3e-21 76.7 11.4 4.3 3 1 1 4 4 4 1 Integrin beta tail domain EGF_2 PF07974.11 001082066.1_37928001_1 - 1.3e-06 28.5 63.5 4.6e-05 23.6 15.0 7.7 7 1 0 7 7 7 4 EGF-like domain Homeobox PF00046.27 001099959.1_37922001_1 - 7.3e-23 80.0 5.3 1.1e-22 79.4 5.3 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001099959.1_37922001_1 - 0.003 17.3 0.1 0.0058 16.4 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain GP38 PF05268.9 001099959.1_37922001_1 - 1.1 8.7 7.8 1.6 8.2 7.8 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 HCO3_cotransp PF00955.19 001195836.1_37928001_1 - 3.6e-243 807.9 8.3 4.6e-243 807.6 8.3 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.11 001195836.1_37928001_1 - 5.6e-106 354.1 0.6 1.7e-105 352.5 0.0 2.1 2 1 0 2 2 2 1 Band 3 cytoplasmic domain DUF4922 PF16269.3 001195836.1_37928001_1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) FAM176 PF14851.4 001195836.1_37928001_1 - 0.34 10.5 2.4 14 5.2 0.5 2.5 2 0 0 2 2 2 0 FAM176 family TALPID3 PF15324.4 001195836.1_37928001_1 - 1.2 6.6 6.3 1.8 6.0 6.3 1.2 1 0 0 1 1 1 0 Hedgehog signalling target Rab5ip PF07019.10 001195836.1_37928001_1 - 1.9 9.0 9.6 6.6 7.3 1.3 3.5 2 1 1 3 3 3 0 Rab5-interacting protein (Rab5ip) FGF PF00167.16 001195837.1_37922001_1 - 6.2e-49 165.1 2.1 7.7e-49 164.8 2.1 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 001195837.1_37922001_1 - 0.0019 18.3 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Fascin domain SNAP-25 PF00835.17 001195838.1_37922001_1 - 6.5e-23 80.7 1.4 6.5e-23 80.7 1.4 2.0 2 0 0 2 2 2 1 SNAP-25 family DUF5089 PF17002.3 001195838.1_37922001_1 - 3.5e-05 23.6 7.0 0.00036 20.3 7.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.6 001195838.1_37922001_1 - 0.0029 17.7 5.9 0.029 14.5 1.3 2.9 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Use1 PF09753.7 001195838.1_37922001_1 - 0.02 14.4 0.7 0.031 13.8 0.1 1.7 2 0 0 2 2 2 0 Membrane fusion protein Use1 RmuC PF02646.14 001195838.1_37922001_1 - 0.032 13.2 1.1 0.81 8.6 0.4 2.1 2 0 0 2 2 2 0 RmuC family SNARE PF05739.17 001195838.1_37922001_1 - 0.038 13.9 0.4 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 SNARE domain DUF1664 PF07889.10 001195838.1_37922001_1 - 0.12 12.2 6.7 0.25 11.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SOAR PF16533.3 001195838.1_37922001_1 - 0.14 12.0 1.3 0.56 10.1 0.1 2.2 2 1 0 2 2 2 0 STIM1 Orai1-activating region DUF16 PF01519.14 001195838.1_37922001_1 - 0.17 12.3 7.3 3.7 8.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Sec20 PF03908.11 001195838.1_37922001_1 - 0.19 11.6 2.7 0.19 11.6 0.6 1.9 2 0 0 2 2 2 0 Sec20 Myb_CC_LHEQLE PF14379.4 001195838.1_37922001_1 - 0.21 11.2 2.5 3.6 7.2 0.1 3.0 2 1 1 3 3 3 0 MYB-CC type transfactor, LHEQLE motif SlyX PF04102.10 001195838.1_37922001_1 - 0.74 10.3 5.4 3.4 8.2 0.7 2.5 2 0 0 2 2 2 0 SlyX DUF4140 PF13600.4 001195838.1_37922001_1 - 1.3 9.4 4.8 6.1 7.2 0.2 2.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) COG6 PF06419.9 001195838.1_37922001_1 - 1.4 6.9 6.5 4.5 5.3 1.1 2.1 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Snapin_Pallidin PF14712.4 001195838.1_37922001_1 - 1.7 9.0 5.8 7.8 6.9 0.7 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Spc7 PF08317.9 001195838.1_37922001_1 - 3.9 6.1 9.4 0.7 8.6 1.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.18 001195838.1_37922001_1 - 6.6 6.6 9.6 0.73 9.7 1.2 2.6 3 0 0 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.9 001195838.1_37922001_1 - 9.1 6.6 8.2 26 5.2 0.8 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Uroplakin_II PF07353.10 001195840.1_37922001_1 - 4.5e-98 325.9 6.0 5e-98 325.7 6.0 1.0 1 0 0 1 1 1 1 Uroplakin II DUF4389 PF14333.4 001195840.1_37922001_1 - 1.3 8.8 5.9 0.61 9.9 3.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) NPC1_N PF16414.3 001082071.1_37929001_1 - 1.4e-83 280.1 8.7 2.7e-83 279.1 8.7 1.5 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.16 001082071.1_37929001_1 - 1.5e-81 274.6 24.5 2.4e-51 174.7 1.5 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.6 001082071.1_37929001_1 - 3.6e-56 189.1 5.4 3.6e-56 189.1 5.4 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.13 001082071.1_37929001_1 - 1.6e-07 30.5 3.4 1.6e-07 30.5 3.4 2.5 2 1 0 2 2 2 1 MMPL family ACR_tran PF00873.17 001082071.1_37929001_1 - 0.051 11.1 17.7 0.011 13.3 9.0 2.2 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family PMP22_Claudin PF00822.18 001099962.1_37922001_3 - 2.2e-40 138.1 17.0 2.6e-40 137.9 17.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001099962.1_37922001_3 - 5.2e-11 42.5 20.5 3.2e-05 23.6 14.5 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Phage_holin_3_6 PF07332.9 001099962.1_37922001_3 - 1.8 8.5 15.7 0.3 11.0 1.3 2.2 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF373 PF04123.11 001099962.1_37922001_3 - 2.7 7.2 5.5 2.6 7.3 4.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Sarcoglycan_1 PF04790.11 001082362.2_37923001_1 - 1.5e-83 280.0 0.0 1.8e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.7 001082362.2_37923001_1 - 0.004 16.9 0.0 0.018 14.8 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) PHA_gran_rgn PF09650.8 001082362.2_37923001_1 - 0.065 13.4 0.0 3.4 7.9 0.0 2.3 1 1 1 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) UcrQ PF02939.14 001198931.1_37922001_2 - 2.8e-32 110.3 0.1 3.7e-32 109.9 0.1 1.2 1 0 0 1 1 1 1 UcrQ family Peptidase_C14 PF00656.20 001099966.1_37923001_1 - 9.3e-45 153.4 0.0 1.5e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain DED PF01335.19 001099966.1_37923001_1 - 1.9e-36 124.0 17.3 4.1e-18 65.3 6.5 2.6 2 0 0 2 2 2 2 Death effector domain RhoGAP PF00620.25 001099966.1_37923001_1 - 0.0032 17.1 0.7 0.049 13.3 0.4 2.5 2 0 0 2 2 2 1 RhoGAP domain Imm30 PF15565.4 001099966.1_37923001_1 - 0.018 15.0 0.3 0.064 13.2 0.3 2.0 1 1 1 2 2 2 0 Immunity protein 30 RD3 PF14473.4 001099966.1_37923001_1 - 0.072 12.8 0.4 0.17 11.6 0.4 1.8 1 1 0 1 1 1 0 RD3 protein COX2_TM PF02790.13 001099966.1_37923001_1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain YqfQ PF14181.4 001099966.1_37923001_1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein GAT PF03127.12 001099966.1_37923001_1 - 1.3 9.3 9.5 0.051 13.8 1.9 2.6 4 0 0 4 4 4 0 GAT domain 7tm_1 PF00001.19 001099967.1_37923001_1 - 6.8e-46 156.5 3.6 1.8e-45 155.1 3.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001099967.1_37923001_1 - 1.2e-08 34.5 2.6 0.00026 20.3 0.4 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.7 001099967.1_37923001_1 - 5.1e-06 25.9 0.2 9.4e-06 25.0 0.0 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.7 001099967.1_37923001_1 - 0.00077 18.8 6.7 0.046 12.9 0.3 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001099967.1_37923001_1 - 0.0095 15.6 5.8 0.021 14.5 0.1 3.0 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.19 001105674.1_37923001_1 - 1.7e-35 122.5 9.9 2.6e-35 121.8 9.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001105674.1_37923001_1 - 7e-05 22.2 11.8 0.0035 16.6 0.2 3.0 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001105674.1_37923001_1 - 0.079 12.5 7.1 0.13 11.8 7.0 1.5 1 1 0 1 1 1 0 Olfactory receptor DUF4149 PF13664.4 001105674.1_37923001_1 - 0.36 11.0 4.4 1.4 9.1 0.1 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4149) RBD-FIP PF09457.8 001082080.1_37928001_1 - 7.2e-17 60.9 2.7 1.2e-16 60.2 2.7 1.4 1 0 0 1 1 1 1 FIP domain p450 PF00067.20 001171131.1_37925001_3 - 1.2e-146 489.0 0.0 1.4e-146 488.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BRICHOS PF04089.12 001109818.1_37922001_1 - 3.2e-17 62.3 0.1 6.9e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 BRICHOS domain RIB43A PF05914.10 001109818.1_37922001_1 - 0.027 13.1 0.0 0.035 12.7 0.0 1.1 1 0 0 1 1 1 0 RIB43A V-set PF07686.15 001171144.1_37921001_1 - 2.3e-19 69.4 0.0 3e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001171144.1_37921001_1 - 0.00015 22.2 0.0 0.0003 21.2 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001171144.1_37921001_1 - 0.11 12.5 0.0 0.36 10.9 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.15 001171145.1_37921001_1 - 1.1e-20 73.7 0.0 1.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001171145.1_37921001_1 - 4.8e-06 27.0 0.0 1e-05 25.9 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001171145.1_37921001_1 - 0.036 14.1 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.14 001171145.1_37921001_1 - 0.17 11.8 0.0 0.93 9.5 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin I-set domain Resistin PF06954.9 001199229.1_37921001_1 - 8.1e-35 119.1 14.2 9.4e-35 118.9 14.2 1.0 1 0 0 1 1 1 1 Resistin CBM_1 PF00734.16 001199229.1_37921001_1 - 0.052 13.4 4.2 0.052 13.4 4.2 2.9 3 1 0 3 3 3 0 Fungal cellulose binding domain MatE PF01554.16 001109820.2_37924001_3 - 1.9e-56 190.0 35.2 1.5e-29 102.6 13.2 3.0 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.4 001109820.2_37924001_3 - 1.9e-07 31.1 8.9 1.9e-07 31.1 8.9 4.0 4 1 1 5 5 5 1 Polysaccharide biosynthesis C-terminal domain DUF2681 PF10883.6 001109820.2_37924001_3 - 0.014 15.6 3.5 0.032 14.5 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) RskA PF10099.7 001109820.2_37924001_3 - 0.044 13.9 6.9 0.85 9.8 0.3 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF2967 PF11179.6 001109820.2_37924001_3 - 0.46 9.8 3.7 0.76 9.0 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) F5_F8_type_C PF00754.23 001109823.1_37922001_1 - 3.8e-27 94.8 0.3 5.1e-27 94.4 0.3 1.2 1 0 0 1 1 1 1 F5/8 type C domain Lyase_N PF09092.9 001109823.1_37922001_1 - 0.035 13.8 0.3 0.063 13.0 0.3 1.4 1 1 0 1 1 1 0 Lyase, N terminal MHC_I_3 PF16497.3 001082088.1_37922001_1 - 3.1e-71 238.8 0.1 4.1e-71 238.4 0.1 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.13 001082088.1_37922001_1 - 3.1e-10 40.2 0.0 7.6e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001082088.1_37922001_1 - 4.4e-05 23.0 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 SelR PF01641.16 001199820.1_37922001_3 - 7.4e-18 64.6 0.2 1.1e-17 64.1 0.2 1.2 1 0 0 1 1 1 1 SelR domain zinc_ribbon_2 PF13240.4 001199820.1_37922001_3 - 0.013 15.0 2.0 1.6 8.4 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Coiled PF05710.10 001199820.1_37922001_3 - 0.11 13.2 0.4 28 5.5 0.0 2.4 2 0 0 2 2 2 0 Coiled coil TFIIS_C PF01096.16 001199820.1_37922001_3 - 1.6 8.5 5.2 17 5.3 0.2 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.4 001199820.1_37922001_3 - 2.2 8.7 5.3 34 4.9 0.1 3.2 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain HRM PF02793.20 001082089.1_37924001_1 - 6.1e-19 67.9 2.3 1.2e-18 67.0 2.3 1.5 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.22 001082089.1_37924001_1 - 6.2e-14 51.8 0.1 8.5e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.22 001082089.1_37924001_2 - 4.8e-70 235.5 9.5 6.6e-70 235.1 9.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) IL8 PF00048.18 001082386.1_37922001_3 - 8.4e-13 48.1 0.3 1.4e-12 47.4 0.3 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like AKAP2_C PF15304.4 001204215.1_37929001_1 - 2.4e-12 46.7 9.5 2.4e-12 46.7 9.5 2.7 2 1 0 2 2 2 1 A-kinase anchor protein 2 C-terminus Uteroglobin PF01099.15 001082092.1_37921001_3 - 8e-19 67.5 0.3 1.3e-18 66.8 0.3 1.3 1 0 0 1 1 1 1 Uteroglobin family Uteroglobin PF01099.15 001082093.1_37921001_2 - 5.2e-17 61.7 0.0 7.7e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Uteroglobin family Uteroglobin PF01099.15 001082094.1_37921001_1 - 1.8e-17 63.1 2.5 2.5e-17 62.7 2.5 1.2 1 0 0 1 1 1 1 Uteroglobin family PLA2_B PF01735.16 001204237.1_37925001_1 - 6.1e-28 97.3 0.0 6e-27 94.0 0.0 2.0 2 0 0 2 2 2 1 Lysophospholipase catalytic domain C2 PF00168.28 001204237.1_37925001_1 - 1.8e-19 69.8 0.1 5.1e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain Uteroglobin PF01099.15 001082095.1_37922001_1 - 2.4e-21 75.5 1.1 3.6e-21 75.0 1.1 1.3 1 0 0 1 1 1 1 Uteroglobin family Cupin_8 PF13621.4 001204238.1_37922001_1 - 1.1e-76 257.9 0.0 1.3e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.20 001204238.1_37922001_1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase EMP24_GP25L PF01105.22 001204345.1_37927001_1 - 1.2e-48 165.4 0.2 2e-48 164.6 0.2 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Uteroglobin PF01099.15 001082096.1_37921001_3 - 1.4e-18 66.7 1.3 1.8e-18 66.4 1.3 1.2 1 0 0 1 1 1 1 Uteroglobin family 7tm_1 PF00001.19 001204444.1_37923001_1 - 4.5e-43 147.3 14.1 6.1e-43 146.8 14.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COPIIcoated_ERV PF07970.10 001171331.1_37923001_1 - 2.1e-94 315.4 1.1 2.6e-94 315.1 1.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.4 001171331.1_37923001_1 - 2.7e-32 110.8 0.1 5.8e-32 109.8 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sad1_UNC PF07738.11 001171332.1_37923001_1 - 2.9e-41 140.5 0.0 4.4e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal IncA PF04156.12 001171332.1_37923001_1 - 0.029 14.0 0.4 0.044 13.5 0.4 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.10 001171332.1_37923001_1 - 0.093 13.2 1.5 0.19 12.2 1.5 1.4 1 0 0 1 1 1 0 SlyX MHC_I PF00129.16 001122937.1_37923001_1 - 2.3e-44 151.0 0.0 3.3e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001122937.1_37923001_1 - 1.3e-06 28.7 0.0 3.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_3 PF16497.3 001122937.1_37923001_1 - 2.8e-05 23.5 0.0 4.7e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 MHC-I family domain DUF3042 PF11240.6 001122937.1_37923001_1 - 0.098 12.6 0.7 0.17 11.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Ig_2 PF13895.4 001122937.1_37923001_1 - 0.13 12.5 0.0 28 5.0 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin domain SKG6 PF08693.8 001122937.1_37923001_1 - 1 8.7 6.1 1.7 8.0 6.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NAD_binding_6 PF08030.10 001082100.1_37924001_3 - 8.5e-39 133.0 0.0 1.4e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.17 001082100.1_37924001_3 - 1.3e-25 89.8 4.9 1.3e-25 89.8 4.9 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.10 001082100.1_37924001_3 - 1.6e-22 79.5 0.0 4.1e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.22 001082100.1_37924001_3 - 1.7e-05 25.0 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.19 001082100.1_37924001_3 - 0.039 14.4 0.0 0.29 11.6 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Ald_Xan_dh_C2 PF02738.16 001122938.1_37929001_2 - 1e-208 694.2 0.0 1.3e-208 693.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001122938.1_37929001_2 - 2.6e-48 163.9 0.0 4.9e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001122938.1_37929001_2 - 2e-33 114.9 0.0 3.6e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001122938.1_37929001_2 - 7.7e-31 105.7 0.2 1.8e-30 104.6 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001122938.1_37929001_2 - 3e-27 94.7 0.0 1.9e-26 92.1 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001122938.1_37929001_2 - 2.8e-09 36.7 1.7 1e-08 34.9 0.2 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SH3_1 PF00018.26 001082101.1_37924001_1 - 6e-23 80.1 0.0 1.9e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 001082101.1_37924001_1 - 7e-22 76.9 0.2 5.9e-12 45.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.15 001082101.1_37924001_1 - 2.9e-19 68.4 0.1 4e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain TPR_1 PF00515.26 001082101.1_37924001_1 - 5.8e-15 54.2 0.7 0.00016 21.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.15 001082101.1_37924001_1 - 1.2e-14 53.0 4.9 0.00083 19.2 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.4 001082101.1_37924001_1 - 1.6e-11 43.4 1.0 0.0017 18.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.4 001082101.1_37924001_1 - 8.8e-09 35.4 4.0 5.3e-05 23.3 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.4 001082101.1_37924001_1 - 9.7e-06 25.1 0.1 0.72 9.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.4 001082101.1_37924001_1 - 1e-05 26.0 2.7 0.043 14.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.4 001082101.1_37924001_1 - 1.4e-05 24.6 0.0 3.2 7.6 0.1 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.22 001082101.1_37924001_1 - 3.5e-05 23.5 0.0 9.4e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.4 001082101.1_37924001_1 - 0.0091 16.0 2.9 0.41 10.7 0.1 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.4 001082101.1_37924001_1 - 0.013 15.7 0.0 4.7 7.7 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC5 PF12862.5 001082101.1_37924001_1 - 0.078 12.9 0.1 0.48 10.4 0.1 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_11 PF13414.4 001082101.1_37924001_1 - 0.11 12.1 0.2 21 4.8 0.0 2.9 2 1 1 3 3 3 0 TPR repeat Cohesin_load PF10345.7 001082101.1_37924001_1 - 0.14 10.4 0.8 0.2 9.9 0.8 1.1 1 0 0 1 1 1 0 Cohesin loading factor TrkA_C PF02080.19 001082101.1_37924001_1 - 0.14 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-C domain TPR_6 PF13174.4 001082101.1_37924001_1 - 0.15 12.7 4.9 7.7 7.3 0.4 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_14 PF13428.4 001082101.1_37924001_1 - 0.35 11.7 3.2 16 6.5 0.1 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF3776 PF12618.6 001171336.1_37927001_1 - 1.3e-26 92.7 13.0 1.3e-26 92.7 13.0 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF3776) PHD PF00628.27 001171336.1_37927001_1 - 5.8e-07 29.2 13.6 1.9e-06 27.5 13.6 2.0 1 0 0 1 1 1 1 PHD-finger DUF1325 PF07039.9 001171336.1_37927001_1 - 0.00011 22.1 0.4 0.00035 20.5 0.0 2.0 2 0 0 2 2 2 1 SGF29 tudor-like domain MBT PF02820.16 001171336.1_37927001_1 - 0.00031 20.9 0.3 0.0025 18.0 0.1 2.5 2 0 0 2 2 2 1 mbt repeat DUF4537 PF15057.4 001171336.1_37927001_1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.8 001171336.1_37927001_1 - 0.0042 16.7 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Tudor-knot PF11717.6 001171336.1_37927001_1 - 0.01 15.6 2.9 0.018 14.8 1.3 2.4 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Rad9_Rad53_bind PF08605.8 001171336.1_37927001_1 - 0.01 15.7 0.1 0.4 10.5 0.1 2.5 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding Bac_rhamnosid_N PF08531.8 001171336.1_37927001_1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Fucokinase PF07959.10 001204806.1_37924001_1 - 8.4e-146 485.9 0.1 1e-145 485.7 0.1 1.1 1 0 0 1 1 1 1 L-fucokinase Hexapep PF00132.22 001204806.1_37924001_1 - 0.058 13.0 0.5 0.058 13.0 0.5 3.0 3 1 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) MDFI PF15316.4 001171338.1_37922001_1 - 1.4e-54 184.9 39.7 1.8e-54 184.6 39.7 1.1 1 0 0 1 1 1 1 MyoD family inhibitor Insulin PF00049.16 001122941.1_37921001_1 - 8.6e-08 32.9 1.0 2.7e-07 31.3 1.0 1.7 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001122941.1_37921001_1 - 0.008 16.0 3.2 0.55 10.1 0.0 2.2 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type IRS PF02174.15 001171340.1_37923001_1 - 2.4e-26 91.4 0.1 4.3e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Kunitz_BPTI PF00014.21 001082104.2_37922001_1 - 3.5e-19 68.6 2.6 8.6e-19 67.4 2.6 1.7 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain WAP PF00095.19 001082104.2_37922001_1 - 8.3e-05 22.8 15.4 0.00032 20.9 15.4 2.0 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' UCH PF00443.27 001171341.1_37925001_1 - 4.8e-57 193.2 0.1 6.8e-57 192.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.17 001171341.1_37925001_1 - 1.3e-20 73.3 6.0 1.3e-20 73.3 6.0 2.9 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.4 001171341.1_37925001_1 - 1.5e-16 60.7 1.2 1.4e-11 44.5 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.4 001171341.1_37925001_1 - 0.022 14.1 5.4 0.95 8.7 0.0 3.6 3 1 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase RAG2_PHD PF13341.4 001171341.1_37925001_1 - 0.14 12.1 2.7 2.3 8.2 0.3 2.7 2 0 0 2 2 2 0 RAG2 PHD domain Stc1 PF12898.5 001171341.1_37925001_1 - 0.73 10.3 6.2 0.77 10.2 0.2 2.8 2 0 0 2 2 2 0 Stc1 domain Glyco_hydro_18 PF00704.26 001082105.1_37924001_3 - 1e-79 268.4 0.0 1.2e-79 268.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Somatostatin PF03002.13 001204934.1_37921001_1 - 1.3e-07 31.3 7.1 2e-07 30.7 7.1 1.2 1 0 0 1 1 1 1 Somatostatin/Cortistatin family Caskin-Pro-rich PF16907.3 001204934.1_37921001_1 - 0.018 15.4 0.2 0.023 15.1 0.2 1.3 1 0 0 1 1 1 0 Proline rich region of Caskin proteins DnaJ PF00226.29 001205004.1_37925001_2 - 1.9e-19 69.4 0.1 4.6e-19 68.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.23 001082109.1_37923001_1 - 1.3e-67 227.8 0.0 1.6e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001082109.1_37923001_1 - 4.5e-30 104.7 0.0 6.2e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001082109.1_37923001_1 - 6.7e-07 28.8 0.0 1.2e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PNRC PF15365.4 001205202.1_37925001_1 - 1.6e-09 38.0 6.5 1.6e-09 38.0 6.5 2.8 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator Sulfate_transp PF00916.18 001142261.1_37925001_1 - 2.9e-106 355.3 20.3 4.1e-106 354.8 20.3 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001142261.1_37925001_1 - 5.4e-23 80.7 0.0 9.9e-23 79.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain RCC1 PF00415.16 001205213.1_37923001_1 - 7.3e-86 282.5 17.9 1.6e-14 54.1 0.0 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 001205213.1_37923001_1 - 9.8e-32 108.0 30.5 6.4e-09 35.3 0.2 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.4 001205213.1_37923001_1 - 0.0014 19.0 1.2 21 5.5 0.0 4.6 6 0 0 6 6 6 1 SUKH-3 immunity protein Peptidase_C25_C PF03785.12 001205213.1_37923001_1 - 0.0037 16.9 0.0 7 6.4 0.0 3.7 5 0 0 5 5 5 2 Peptidase family C25, C terminal ig-like domain Ribosomal_L23eN PF03939.11 001205224.1_37922001_1 - 4.7e-28 97.0 17.1 4.7e-28 97.0 17.1 2.3 3 0 0 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.18 001205224.1_37922001_1 - 3.9e-16 59.1 3.1 3.9e-16 59.1 3.1 2.8 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L6 PF00347.21 001205224.1_37922001_1 - 0.045 14.3 1.1 0.087 13.4 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein L6 Cpn60_TCP1 PF00118.22 001142262.1_37924001_2 - 6.6e-147 490.0 12.6 7.5e-147 489.7 12.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2529 PF10740.7 001142262.1_37924001_2 - 0.0068 15.9 0.4 0.022 14.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2529) Ribosomal_S13 PF00416.20 001142262.1_37924001_2 - 0.18 12.0 1.0 0.66 10.2 0.3 2.2 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Septin PF00735.16 001171349.1_37923001_1 - 1e-98 329.9 1.5 1e-98 329.9 1.5 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.21 001171349.1_37923001_1 - 4e-07 30.0 0.2 1.3e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.11 001171349.1_37923001_1 - 5.6e-05 23.2 0.1 0.00021 21.4 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.25 001171349.1_37923001_1 - 0.00011 21.7 5.1 1.1 8.6 0.5 3.2 3 0 0 3 3 3 3 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001171349.1_37923001_1 - 0.00011 22.0 2.7 0.0021 17.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_22 PF13401.4 001171349.1_37923001_1 - 0.00014 22.0 0.2 0.00047 20.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.4 001171349.1_37923001_1 - 0.00063 20.0 0.2 0.0022 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.20 001171349.1_37923001_1 - 0.011 15.2 3.0 0.017 14.6 0.0 2.5 2 0 0 2 2 2 0 Ras family AIG1 PF04548.14 001171349.1_37923001_1 - 0.013 14.7 5.8 0.017 14.3 0.0 2.3 2 0 0 2 2 2 0 AIG1 family RNA_helicase PF00910.20 001171349.1_37923001_1 - 0.026 14.8 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.25 001171349.1_37923001_1 - 0.028 14.8 0.0 0.028 14.8 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.4 001171349.1_37923001_1 - 0.052 13.1 0.3 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Microtub_bd PF16796.3 001171349.1_37923001_1 - 0.054 13.3 2.8 0.071 12.9 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding AAA_29 PF13555.4 001171349.1_37923001_1 - 0.13 11.8 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.4 001171349.1_37923001_1 - 0.16 10.6 16.7 3 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.15 001171349.1_37923001_1 - 0.56 10.1 6.2 0.73 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.4 001171349.1_37923001_1 - 0.88 9.9 20.4 1.3 9.4 0.8 2.5 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.21 001171349.1_37923001_1 - 2.4 8.0 7.8 8.1 6.3 0.0 3.2 2 1 1 3 3 3 0 Dynamin family Atg14 PF10186.7 001171349.1_37923001_1 - 2.7 6.8 13.5 5.8 5.8 13.5 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_L35Ae PF01247.16 001205225.1_37921001_3 - 1.5e-47 159.6 0.3 1.8e-47 159.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.16 001205225.1_37921001_3 - 0.025 14.7 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain DUF2080 PF09853.7 001205225.1_37921001_3 - 0.1 12.3 0.2 0.36 10.5 0.0 2.0 2 1 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) Cpn60_TCP1 PF00118.22 001142260.1_37924001_1 - 8e-159 529.3 2.1 9.1e-159 529.1 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EF-hand_1 PF00036.30 001082112.1_37924001_2 - 4.2e-25 85.3 9.3 4.7e-07 28.8 0.7 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.4 001082112.1_37924001_2 - 2.7e-23 79.7 9.1 3.4e-07 29.6 0.4 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.4 001082112.1_37924001_2 - 9.1e-21 74.0 8.4 3.4e-09 36.9 2.7 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.4 001082112.1_37924001_2 - 7.2e-14 50.5 7.6 0.0049 16.2 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.4 001082112.1_37924001_2 - 1.9e-06 27.4 6.6 0.00086 18.9 0.2 3.8 4 0 0 4 4 4 2 EF-hand domain pair GPHH PF16905.3 001082112.1_37924001_2 - 0.002 17.8 0.0 0.97 9.2 0.0 3.0 3 0 0 3 3 3 1 Voltage-dependent L-type calcium channel, IQ-associated Caleosin PF05042.11 001082112.1_37924001_2 - 0.067 13.0 1.9 34 4.2 0.1 3.7 2 1 2 4 4 4 0 Caleosin related protein SPARC_Ca_bdg PF10591.7 001082112.1_37924001_2 - 0.55 10.4 3.5 19 5.5 0.0 3.4 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.4 001082112.1_37924001_2 - 2.8 7.7 7.3 6.2 6.6 0.2 3.8 3 1 1 4 4 4 0 EF hand ASC PF00858.22 001171017.1_37924001_1 - 5.4e-94 315.3 0.0 6.2e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF3528 PF12045.6 001206421.1_37923001_1 - 1.3e-41 142.4 0.0 6.9e-22 78.5 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3528) Homeobox PF00046.27 001206421.1_37923001_1 - 2.3e-20 72.0 8.0 3.2e-20 71.6 8.0 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001206421.1_37923001_1 - 0.048 13.4 0.6 0.083 12.7 0.6 1.3 1 0 0 1 1 1 0 Homeobox KN domain MerR_1 PF13411.4 001206421.1_37923001_1 - 0.14 12.1 0.4 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 MerR HTH family regulatory protein KOG2701 PF09762.7 001171023.1_37924001_1 - 4.5e-78 261.4 0.0 4.5e-78 261.4 0.0 4.0 3 2 0 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) DUF4107 PF13389.4 001171023.1_37924001_1 - 0.19 11.8 3.3 0.43 10.6 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4107) EIF4E-T PF10477.7 001171353.1_37926001_1 - 2.2e-170 568.5 8.8 5.5e-170 567.2 8.8 1.7 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Glycolytic PF00274.17 001171353.1_37926001_1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I ADK PF00406.20 001082114.1_37922001_1 - 1.2e-51 174.7 0.0 1.5e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.4 001082114.1_37922001_1 - 5.3e-20 72.1 0.0 1.3e-19 70.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.12 001082114.1_37922001_1 - 2e-15 56.4 0.0 3.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.4 001082114.1_37922001_1 - 4.1e-08 33.7 0.0 7.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001082114.1_37922001_1 - 0.0025 17.8 0.5 0.026 14.5 0.2 2.4 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.16 001082114.1_37922001_1 - 0.064 12.9 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase DUF3645 PF12359.6 001082114.1_37922001_3 - 0.021 14.1 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) Ribosomal_S10 PF00338.20 001253734.1_37922001_2 - 1.8e-30 104.9 0.3 2.5e-30 104.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ion_trans PF00520.29 001143934.1_37925001_2 - 1.1e-45 155.7 50.6 2.6e-30 105.3 23.4 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.10 001143934.1_37925001_2 - 0.49 8.9 40.5 0.15 10.6 5.5 4.4 3 1 1 4 4 4 0 Polycystin cation channel 14-3-3 PF00244.18 001171356.1_37922001_1 - 5.3e-104 346.4 8.9 6e-104 346.2 8.9 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF722 PF05263.9 001171356.1_37922001_1 - 0.023 14.8 0.8 0.06 13.4 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF722) CodY PF06018.12 001171356.1_37922001_1 - 0.06 12.7 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 CodY GAF-like domain MHC_I_3 PF16497.3 001160282.1_37923001_2 - 8e-78 260.3 0.5 1.1e-77 259.9 0.5 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.13 001160282.1_37923001_2 - 3.9e-10 39.9 0.0 7.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001160282.1_37923001_2 - 0.00062 19.2 0.0 0.00097 18.6 0.0 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_3 PF13927.4 001160282.1_37923001_2 - 0.0052 17.2 0.0 0.063 13.8 0.0 2.3 1 1 1 2 2 2 1 Immunoglobulin domain ig PF00047.23 001160282.1_37923001_2 - 0.016 15.3 0.0 1.2 9.3 0.0 2.4 1 1 1 2 2 2 0 Immunoglobulin domain Gag_p10 PF02337.15 001160282.1_37923001_2 - 0.11 12.3 0.2 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 Retroviral GAG p10 protein SKG6 PF08693.8 001160282.1_37923001_2 - 2.2 7.6 5.4 4.6 6.6 5.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TNF PF00229.16 001256781.1_37922001_1 - 1.1e-28 99.5 0.7 2.3e-28 98.5 0.4 1.6 2 0 0 2 2 2 1 TNF(Tumour Necrosis Factor) family dDENN PF03455.17 001256781.1_37922001_1 - 0.08 12.8 0.3 9.8 6.1 0.1 2.7 2 0 0 2 2 2 0 dDENN domain PI31_Prot_N PF11566.6 001171360.1_37924001_1 - 3.5e-16 59.3 0.0 2.5e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 PI31 proteasome regulator N-terminal F-box-like PF12937.5 001171360.1_37924001_1 - 1.5e-07 31.1 5.0 3.1e-07 30.0 5.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001171360.1_37924001_1 - 0.0013 18.4 3.8 0.0027 17.4 3.8 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.9 001171360.1_37924001_1 - 0.013 15.8 0.1 0.028 14.8 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Synapsin_C PF02750.12 001171361.1_37924001_1 - 7.8e-136 450.0 0.8 9.8e-136 449.6 0.8 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.14 001171361.1_37924001_1 - 1.1e-44 150.7 0.0 8.2e-44 147.9 0.0 2.3 2 1 1 3 3 3 1 Synapsin, N-terminal domain Synapsin_N PF10581.7 001171361.1_37924001_1 - 2.9e-20 71.8 3.1 6.3e-20 70.7 3.1 1.6 1 0 0 1 1 1 1 Synapsin N-terminal RimK PF08443.9 001171361.1_37924001_1 - 0.004 16.6 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Coleoptericin PF06286.9 001171361.1_37924001_1 - 0.054 13.5 0.3 0.16 11.9 0.3 1.8 1 0 0 1 1 1 0 Coleoptericin ABC_membrane_2 PF06472.13 001171362.1_37925001_1 - 2.3e-100 335.5 4.5 3.3e-100 334.9 4.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.25 001171362.1_37925001_1 - 4.7e-17 62.6 0.0 8.8e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.4 001171362.1_37925001_1 - 0.00033 20.4 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Cyto_heme_lyase PF01265.15 001171362.1_37925001_1 - 0.0016 18.0 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase AAA_23 PF13476.4 001171362.1_37925001_1 - 0.012 16.1 2.0 0.012 16.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.4 001171362.1_37925001_1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.17 001171362.1_37925001_1 - 0.05 12.9 0.0 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.4 001171362.1_37925001_1 - 0.055 13.7 0.1 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain TBCA PF02970.14 001171362.1_37925001_1 - 0.097 12.9 2.6 7.1 6.9 0.4 2.4 2 0 0 2 2 2 0 Tubulin binding cofactor A Rad17 PF03215.13 001171362.1_37925001_1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Adeno_IVa2 PF02456.13 001171362.1_37925001_1 - 0.14 10.8 0.4 0.35 9.5 0.1 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein ARID PF01388.19 001171362.1_37925001_1 - 0.17 12.4 0.2 0.81 10.3 0.0 2.1 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain TRAP-delta PF05404.10 001171364.1_37922001_1 - 1.7e-67 225.8 0.0 2e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) GSHPx PF00255.17 001256900.1_37924001_2 - 1.1e-37 127.8 0.1 1.7e-37 127.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase 7tm_1 PF00001.19 001160278.1_37923001_3 - 3.1e-55 187.2 21.9 4e-55 186.8 21.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001160278.1_37923001_3 - 1.7e-09 37.3 20.6 4.7e-09 35.9 20.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TRP PF06011.10 001160278.1_37923001_3 - 0.1 11.1 14.5 0.055 12.0 3.4 2.5 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel DUF4079 PF13301.4 001160278.1_37923001_3 - 0.39 10.7 2.8 7.6 6.5 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Git3 PF11710.6 001160278.1_37923001_3 - 1.8 8.1 17.8 0.14 11.8 12.1 2.0 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Voltage_CLC PF00654.18 001160278.1_37923001_3 - 7 5.6 9.6 0.16 11.0 2.4 1.7 2 0 0 2 2 2 0 Voltage gated chloride channel SR-25 PF10500.7 001082119.1_37924001_2 - 0.72 9.3 25.9 1.2 8.6 25.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med19 PF10278.7 001082119.1_37924001_2 - 8.4 6.1 22.9 13 5.5 22.9 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Annexin PF00191.18 001082119.1_37924001_3 - 2.3e-96 315.8 14.0 1.1e-25 89.4 0.7 4.2 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.4 001082119.1_37924001_3 - 0.087 13.2 2.2 15 6.0 0.0 3.6 3 1 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GSHPx PF00255.17 001256904.1_37923001_3 - 1.8e-38 130.3 0.1 2.7e-38 129.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 001256904.1_37923001_3 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.12 001256904.1_37923001_3 - 0.021 14.5 0.0 0.45 10.2 0.0 2.5 3 0 0 3 3 3 0 SCO1/SenC Cyclin_N2 PF16500.3 001257364.1_37923001_1 - 3.3e-50 170.2 2.3 5.1e-50 169.7 2.3 1.3 1 0 0 1 1 1 1 N-terminal region of cyclin_N Cyclin_N PF00134.21 001257364.1_37923001_1 - 1.2e-48 163.9 0.2 2.1e-48 163.2 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001257364.1_37923001_1 - 1.3e-26 92.9 0.1 4.8e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Sororin PF09666.8 001257364.1_37923001_1 - 0.023 14.8 1.4 0.047 13.8 1.4 1.6 1 0 0 1 1 1 0 Sororin protein LEM PF03020.13 001171372.1_37922001_1 - 1.4e-15 56.4 0.0 2.5e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 LEM domain Filamin PF00630.17 001171373.1_37925001_1 - 4.5e-126 412.8 3.1 1.5e-19 70.6 0.0 8.2 8 0 0 8 8 8 8 Filamin/ABP280 repeat DUF5060 PF16586.3 001171373.1_37925001_1 - 2.6e-06 27.6 0.0 0.94 9.8 0.0 6.1 8 0 0 8 8 8 2 Domain of unknown function (DUF5060) Y_Y_Y PF07495.11 001171373.1_37925001_1 - 4.3e-06 26.4 0.5 3 7.7 0.0 4.7 5 0 0 5 5 5 3 Y_Y_Y domain PapC_N PF13954.4 001171373.1_37925001_1 - 0.016 15.0 0.0 0.5 10.2 0.0 3.3 4 1 1 5 5 5 0 PapC N-terminal domain Aldo_ket_red PF00248.19 001267588.1_37923001_3 - 4.7e-58 196.5 0.0 6.3e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.16 001267588.1_37923001_3 - 0.12 12.5 0.1 7.6 6.7 0.0 2.6 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_L16 PF00252.16 001171374.1_37922001_1 - 1.5e-44 151.1 0.3 1.8e-44 150.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e TNFR_c6 PF00020.16 001267705.1_37923001_1 - 3.9e-24 84.6 47.8 6.3e-09 36.0 6.2 4.5 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.11 001267705.1_37923001_1 - 0.0082 15.8 1.2 0.0082 15.8 1.2 4.4 3 2 2 5 5 5 3 Putative ephrin-receptor like Acyltransferase PF01553.19 001171376.1_37922001_1 - 6.3e-43 145.5 0.0 8.6e-43 145.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase SEFIR PF08357.9 001270479.1_37924001_2 - 1.8e-35 122.3 0.1 3e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.4 001270479.1_37924001_2 - 5.9e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 TIR domain ATP-synt_S1 PF05827.10 001171377.1_37923001_1 - 3e-54 182.7 0.6 4.4e-54 182.1 0.6 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.15 001171377.1_37923001_1 - 0.016 14.6 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Plexin_cytopl PF08337.10 001171380.1_37929001_1 - 1.3e-251 836.0 1.4 1.6e-251 835.7 1.4 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.17 001171380.1_37929001_1 - 1.2e-73 248.2 0.0 1.7e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Sema domain TIG PF01833.22 001171380.1_37929001_1 - 9.7e-42 140.8 9.8 2.2e-11 43.6 0.7 6.0 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.23 001171380.1_37929001_1 - 2.8e-18 66.1 58.0 2.4e-08 34.2 13.3 3.7 3 0 0 3 3 3 3 Plexin repeat adh_short_C2 PF13561.4 001277089.1_37922001_1 - 1.3e-55 188.4 0.0 1.8e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001277089.1_37922001_1 - 6.4e-50 169.2 0.6 8.1e-50 168.9 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001277089.1_37922001_1 - 1.4e-11 44.5 0.9 2e-11 44.0 0.9 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.8 001277089.1_37922001_1 - 0.00012 21.4 0.1 0.00027 20.2 0.1 1.5 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.4 001277089.1_37922001_1 - 0.00083 19.2 0.7 0.0012 18.7 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.17 001277089.1_37922001_1 - 0.0068 15.6 0.1 0.026 13.7 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain YjeF_N PF03853.13 001277089.1_37922001_1 - 0.013 15.3 0.6 0.026 14.3 0.5 1.5 1 1 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.19 001277089.1_37922001_1 - 0.028 13.7 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.19 001277089.1_37922001_1 - 0.047 13.6 2.0 0.055 13.4 0.7 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ald_Xan_dh_C2 PF02738.16 001278863.1_37929001_1 - 3.6e-185 616.4 0.0 5e-185 615.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001278863.1_37929001_1 - 4.2e-41 140.4 0.0 8.4e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001278863.1_37929001_1 - 1.6e-30 105.6 4.0 4.1e-30 104.2 4.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001278863.1_37929001_1 - 7.4e-30 102.6 0.3 2e-29 101.2 0.3 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001278863.1_37929001_1 - 1e-27 96.1 0.2 2e-26 92.0 0.0 3.0 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001278863.1_37929001_1 - 2.4e-09 36.9 1.8 1.2e-08 34.7 0.2 2.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.15 001278863.1_37929001_1 - 0.069 13.0 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain Urease_beta PF00699.18 001278863.1_37929001_1 - 0.12 12.2 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Urease beta subunit Cpn60_TCP1 PF00118.22 001163114.1_37924001_1 - 2.4e-156 521.0 11.9 2.8e-156 520.9 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FUN14 PF04930.13 001171385.1_37922001_1 - 4.2e-28 97.5 3.9 6.1e-28 96.9 3.9 1.2 1 0 0 1 1 1 1 FUN14 family Romo1 PF10247.7 001171385.1_37922001_1 - 0.091 13.0 4.9 4.2 7.6 0.2 2.4 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 7tm_2 PF00002.22 001163115.2_37923001_2 - 2.2e-78 262.8 19.5 2.8e-78 262.5 19.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.20 001163115.2_37923001_2 - 7.9e-17 61.2 1.1 1.6e-16 60.2 1.1 1.6 1 0 0 1 1 1 1 Hormone receptor domain SNF PF00209.16 001163116.1_37924001_1 - 6.7e-174 579.3 32.7 9.1e-174 578.9 32.7 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family YiaAB PF05360.12 001163116.1_37924001_1 - 8.4 6.6 11.3 8.8 6.5 1.1 4.0 2 0 0 2 2 2 0 yiaA/B two helix domain ARD PF03079.12 001285837.1_37922001_1 - 3.9e-59 199.2 0.1 4.5e-59 199.0 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.9 001285837.1_37922001_1 - 2.9e-09 36.4 0.0 4.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.17 001285837.1_37922001_1 - 6.6e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.20 001285837.1_37922001_1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.10 001285837.1_37922001_1 - 0.036 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_8 PF13621.4 001285837.1_37922001_1 - 0.069 12.8 0.0 0.88 9.2 0.0 2.0 1 1 0 1 1 1 0 Cupin-like domain RNase_H PF00075.22 001285838.1_37922001_1 - 3.1e-46 157.0 0.0 5.7e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285838.1_37922001_1 - 1.7e-19 69.7 0.8 3.7e-19 68.6 0.8 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285838.1_37922001_1 - 0.00097 18.7 0.0 0.0032 17.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase-like Aldo_ket_red PF00248.19 001287559.1_37923001_1 - 2.1e-55 187.8 0.0 2.6e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Homeobox PF00046.27 001171397.1_37923001_1 - 7.4e-22 76.8 6.9 1.1e-21 76.2 6.9 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.27 001171398.1_37923001_1 - 1.6e-21 75.7 6.2 2.8e-21 74.9 6.2 1.4 1 0 0 1 1 1 1 Homeobox domain DUF4074 PF13293.4 001171399.1_37923001_1 - 5.8e-32 109.7 7.8 1.7e-31 108.1 7.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4074) Homeobox PF00046.27 001171399.1_37923001_1 - 2.2e-21 75.3 4.9 4.1e-21 74.4 4.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001171399.1_37923001_1 - 3.1 7.6 7.4 0.81 9.5 0.7 2.9 3 0 0 3 3 3 0 Homeobox KN domain Ribosomal_S14 PF00253.19 001289812.1_37921001_3 - 1e-14 53.9 2.8 1.3e-14 53.5 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Homeobox PF00046.27 001171400.1_37922001_1 - 2.4e-22 78.4 8.5 3.6e-22 77.8 8.5 1.3 1 0 0 1 1 1 1 Homeobox domain DUF2209 PF09974.7 001171400.1_37922001_1 - 0.14 12.4 0.1 0.19 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) MAPEG PF01124.16 001082138.1_37921001_2 - 3.6e-24 85.0 0.7 4.2e-24 84.8 0.7 1.1 1 0 0 1 1 1 1 MAPEG family Homeobox PF00046.27 001171402.1_37922001_1 - 1.5e-21 75.9 8.1 2.1e-21 75.4 8.1 1.2 1 0 0 1 1 1 1 Homeobox domain Ribosomal_60s PF00428.17 001171402.1_37922001_1 - 0.0013 19.1 18.9 0.0026 18.1 18.9 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Auxin_canalis PF05703.9 001171402.1_37922001_1 - 0.0014 18.5 2.0 0.0019 18.1 2.0 1.1 1 0 0 1 1 1 1 Auxin canalisation NOA36 PF06524.10 001171402.1_37922001_1 - 0.033 13.4 2.6 0.044 13.0 2.6 1.1 1 0 0 1 1 1 0 NOA36 protein PMSI1 PF15322.4 001171402.1_37922001_1 - 0.82 8.9 5.7 1.1 8.5 5.7 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Orn_Arg_deC_N PF02784.14 001292042.1_37929001_2 - 7.2e-63 212.2 0.1 9.4e-63 211.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001292042.1_37929001_2 - 1.1e-23 83.4 0.0 1.9e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Uteroglobin PF01099.15 001082139.1_37921001_1 - 3.6e-15 55.8 0.1 5.7e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Uteroglobin family IRK PF01007.18 001082140.1_37923001_1 - 5.7e-139 462.5 3.4 6.9e-139 462.3 3.4 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel EI24 PF07264.9 001082140.1_37923001_1 - 0.45 10.6 4.2 0.76 9.9 4.2 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) LBP_BPI_CETP_C PF02886.15 001082141.1_37924001_3 - 4.6e-76 255.3 0.0 6.2e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.23 001082141.1_37924001_3 - 9.2e-32 109.8 0.0 1.8e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain MDFI PF15316.4 001171407.1_37922001_1 - 3.1e-73 245.8 36.1 3.1e-73 245.8 36.1 1.6 2 0 0 2 2 2 1 MyoD family inhibitor Lectin_C PF00059.19 001297476.1_37922001_1 - 6e-16 59.0 0.8 6e-16 59.0 0.8 1.7 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.10 001297476.1_37922001_1 - 0.0006 19.4 1.6 0.0044 16.6 0.2 2.2 2 1 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like FYVE_2 PF02318.14 001297485.1_37924001_1 - 6.1e-47 158.6 5.7 1.1e-46 157.7 5.7 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Rab_eff_C PF04698.10 001297485.1_37924001_1 - 2.8e-13 49.0 3.5 3.2e-11 42.1 0.5 2.1 2 0 0 2 2 2 2 Rab effector MyRIP/melanophilin C-terminus FYVE PF01363.19 001297485.1_37924001_1 - 0.0041 17.1 7.3 0.0096 15.9 7.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger IncA PF04156.12 001297485.1_37924001_1 - 0.15 11.8 3.1 2.3 7.9 0.0 2.9 3 0 0 3 3 3 0 IncA protein Nup54 PF13874.4 001297485.1_37924001_1 - 0.15 12.0 4.9 7 6.6 0.2 2.8 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DUF4140 PF13600.4 001297485.1_37924001_1 - 2.1 8.7 9.3 0.4 11.0 0.5 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Uso1_p115_C PF04871.11 001297485.1_37924001_1 - 7.4 6.8 12.6 2.7 8.3 2.2 3.0 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Rhomboid_SP PF12595.6 001171412.1_37926001_1 - 4.2e-112 372.6 2.6 6.5e-112 372.0 2.6 1.3 1 0 0 1 1 1 1 Rhomboid serine protease Rhomboid PF01694.20 001171412.1_37926001_1 - 4.2e-28 98.1 8.5 4.2e-28 98.1 8.5 1.7 2 0 0 2 2 2 1 Rhomboid family Ald_Xan_dh_C2 PF02738.16 001297488.1_37929001_1 - 1e-186 621.5 0.0 1.4e-186 621.1 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001297488.1_37929001_1 - 8.9e-41 139.3 0.0 2.6e-40 137.8 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001297488.1_37929001_1 - 1.9e-31 108.6 0.4 4.1e-31 107.4 0.4 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001297488.1_37929001_1 - 8.3e-31 105.6 0.2 1.9e-30 104.5 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001297488.1_37929001_1 - 7.4e-28 96.6 0.0 4.7e-26 90.8 0.0 2.7 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001297488.1_37929001_1 - 2.1e-08 33.9 0.3 2.1e-08 33.9 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001297488.1_37929001_1 - 0.002 17.8 2.7 0.0067 16.1 2.7 2.0 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NPR3 PF03666.11 001171413.2_37925001_3 - 1.4e-48 165.7 3.4 8.3e-40 136.8 2.6 2.5 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.9 001171413.2_37925001_3 - 0.0015 17.3 0.0 0.42 9.2 0.0 2.3 2 0 0 2 2 2 2 Nitrogen permease regulator 2 Ank_2 PF12796.5 001297491.1_37925001_1 - 8.4e-27 93.5 6.2 2.2e-12 47.2 0.2 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001297491.1_37925001_1 - 9.7e-23 80.1 3.2 2.8e-05 24.5 0.0 5.9 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.28 001297491.1_37925001_1 - 2.7e-20 71.7 8.3 0.004 17.4 0.0 6.9 5 2 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.4 001297491.1_37925001_1 - 3.6e-20 69.8 3.6 0.062 13.7 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.4 001297491.1_37925001_1 - 3.7e-12 46.1 7.7 0.0012 19.0 0.1 5.9 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Syja_N PF02383.16 001171417.1_37929001_1 - 1.6e-70 237.8 0.3 2.4e-70 237.2 0.3 1.3 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.9 001171417.1_37929001_1 - 7.4e-60 200.9 0.3 1.7e-59 199.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.21 001171417.1_37929001_1 - 2e-09 37.5 0.0 5.1e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.20 001171417.1_37929001_1 - 0.016 14.9 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0220 PF05255.9 001171419.1_37921001_1 - 1.2e-50 171.1 3.9 1.4e-50 171.0 3.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF2633 PF11119.6 001171419.1_37921001_1 - 8.8 6.3 6.3 1.4 8.9 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Aldo_ket_red PF00248.19 001297497.1_37922001_1 - 2.3e-55 187.7 0.0 2.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Erp_C PF06780.9 001297497.1_37922001_1 - 0.016 15.0 0.0 6.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Erp protein C-terminus GARS_A PF01071.17 001171420.1_37927001_1 - 8.2e-91 302.9 0.0 2e-90 301.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.17 001171420.1_37927001_1 - 6.4e-66 221.4 0.1 1.3e-65 220.5 0.1 1.5 1 0 0 1 1 1 1 Formyl transferase AIRS_C PF02769.20 001171420.1_37927001_1 - 1.4e-39 135.6 0.0 9.1e-39 132.9 0.0 2.5 3 0 0 3 3 3 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.13 001171420.1_37927001_1 - 5.3e-36 123.1 1.3 4.7e-34 116.9 0.3 3.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.14 001171420.1_37927001_1 - 1e-29 102.5 1.0 3.7e-28 97.5 0.3 2.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.22 001171420.1_37927001_1 - 1e-16 61.2 0.3 5.2e-16 58.9 0.3 2.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.4 001171420.1_37927001_1 - 5.2e-10 38.4 0.1 1.3e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.15 001171420.1_37927001_1 - 2.4e-05 23.8 0.3 0.00012 21.5 0.1 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.12 001171420.1_37927001_1 - 2.6e-05 24.2 0.0 6.8e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.20 001171420.1_37927001_1 - 7.1e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.4 001171420.1_37927001_1 - 0.00058 19.3 0.1 0.0014 18.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.8 001171420.1_37927001_1 - 0.00078 18.9 0.1 0.0019 17.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain DUF498 PF04430.12 001171420.1_37927001_1 - 0.017 15.1 0.1 1.9 8.4 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF498/DUF598) Dala_Dala_lig_C PF07478.11 001171420.1_37927001_1 - 0.02 14.3 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus RimK PF08443.9 001171420.1_37927001_1 - 0.021 14.3 0.0 0.059 12.8 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Aldo_ket_red PF00248.19 001297499.1_37922001_1 - 2.4e-58 197.5 0.0 2.9e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PKD PF00801.18 001297728.1_37925001_2 - 3.7e-14 52.2 0.2 1.8e-13 50.0 0.0 2.4 2 0 0 2 2 2 1 PKD domain PetG PF02529.13 001297728.1_37925001_2 - 0.23 11.2 1.8 0.5 10.1 1.8 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Pox_vIL-18BP PF05566.10 001297729.1_37922001_1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Orthopoxvirus interleukin 18 binding protein IL15 PF02372.13 001301260.1_37923001_1 - 0.0025 17.7 0.0 0.0047 16.8 0.0 1.4 1 1 0 1 1 1 1 Interleukin 15 Uteroglobin PF01099.15 001082157.2_37922001_1 - 3.7e-13 49.4 0.0 5.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Uteroglobin family C1-set PF07654.13 001082158.1_37922001_1 - 5e-25 87.7 0.0 6.6e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.23 001082158.1_37922001_1 - 4.1e-05 23.5 0.2 5.9e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001082158.1_37922001_1 - 0.022 14.7 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.4 001082158.1_37922001_1 - 0.028 14.9 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Rsm22 PF09243.8 001082160.1_37923001_1 - 2.2 7.3 4.5 3.5 6.7 4.5 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RRM_1 PF00076.20 001082160.1_37923001_2 - 7.7e-29 99.2 1.2 2.6e-14 52.7 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001082160.1_37923001_2 - 7.8e-08 31.8 0.0 0.0075 15.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001082160.1_37923001_2 - 1.9e-07 30.7 0.0 0.001 18.7 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.4 001082160.1_37923001_2 - 0.0081 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) UNC-79 PF14776.4 001306216.1_37921001_2 - 0.04 12.5 0.0 0.047 12.3 0.0 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Ald_Xan_dh_C2 PF02738.16 001308460.1_37929001_2 - 9.3e-186 618.3 0.1 1.3e-185 617.9 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001308460.1_37929001_2 - 3.7e-42 143.8 0.2 1e-41 142.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.15 001308460.1_37929001_2 - 1.5e-32 111.7 0.2 4.6e-29 100.5 0.0 2.9 3 0 0 3 3 3 2 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.20 001308460.1_37929001_2 - 8.3e-30 103.3 1.4 1.6e-29 102.4 1.4 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001308460.1_37929001_2 - 5.1e-29 99.9 0.3 1.4e-28 98.5 0.3 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.25 001308460.1_37929001_2 - 2.2e-07 30.6 0.6 5.3e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain IL8 PF00048.18 001082162.1_37922001_2 - 2.3e-11 43.5 0.3 3.3e-11 43.0 0.3 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Mtp PF03821.14 001082639.1_37923001_3 - 6.8e-19 68.3 15.4 2.9e-14 53.1 5.8 2.3 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter adh_short PF00106.23 001319581.1_37922001_1 - 6.4e-08 32.1 0.3 1.2e-07 31.3 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001319581.1_37922001_1 - 1.3e-05 24.7 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.19 001319581.1_37922001_1 - 0.00061 19.2 0.0 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ACT_5 PF13710.4 001319581.1_37922001_1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 ACT domain HCO3_cotransp PF00955.19 001319583.1_37928001_2 - 5.3e-248 823.8 5.7 6.7e-248 823.5 5.7 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.11 001319583.1_37928001_2 - 1.2e-105 353.1 0.1 2e-105 352.3 0.1 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain COesterase PF00135.26 001101711.1_37924001_1 - 1.3e-151 505.9 0.0 1.6e-151 505.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.11 001101711.1_37924001_1 - 4.4e-07 29.8 0.0 1.3e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001101711.1_37924001_1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Sugar_tr PF00083.22 001082169.1_37926001_1 - 6.8e-08 31.7 0.2 9.9e-08 31.1 0.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001082169.1_37926001_2 - 1.2e-27 96.6 23.9 1.2e-27 96.6 23.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 001082169.1_37926001_2 - 1.4e-26 93.2 19.2 2.3e-26 92.6 19.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter ITI_HC_C PF06668.10 001082646.1_37926001_3 - 8.7e-62 208.0 0.0 1.5e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.8 001082646.1_37926001_3 - 4.9e-27 94.3 0.7 1e-26 93.2 0.7 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.26 001082646.1_37926001_3 - 7e-19 68.6 0.0 1.1e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.4 001082646.1_37926001_3 - 9.1e-16 58.0 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.4 001082646.1_37926001_3 - 7.2e-11 42.6 0.0 1.5e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.12 001082646.1_37926001_3 - 0.0056 16.0 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Peptidase_S49_N PF08496.8 001082646.1_37926001_3 - 0.087 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ITI_HC_C PF06668.10 001082647.2_37927001_1 - 1.1e-71 240.2 0.0 1.9e-71 239.5 0.0 1.4 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.8 001082647.2_37927001_1 - 8.5e-32 109.6 0.4 1.8e-31 108.5 0.4 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.26 001082647.2_37927001_1 - 1.4e-22 80.6 2.1 2.4e-22 79.9 2.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.4 001082647.2_37927001_1 - 1.3e-16 60.7 0.0 2.1e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.4 001082647.2_37927001_1 - 6.7e-12 45.9 0.1 2.1e-11 44.3 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.12 001082647.2_37927001_1 - 0.00059 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF4561 PF15120.4 001082647.2_37927001_1 - 0.022 14.4 0.4 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4561) DUF2201 PF09967.7 001082647.2_37927001_1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) APS_kinase PF01583.18 001082172.1_37924001_1 - 1.9e-75 252.0 0.0 3.3e-75 251.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.15 001082172.1_37924001_1 - 3.8e-71 238.8 0.1 5.4e-71 238.3 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.4 001082172.1_37924001_1 - 2.2e-48 163.8 0.0 4.3e-48 162.8 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.4 001082172.1_37924001_1 - 2.5e-07 30.8 0.0 6.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001082172.1_37924001_1 - 0.00028 21.3 0.0 0.0014 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.16 001082172.1_37924001_1 - 0.043 13.0 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.15 001082172.1_37924001_1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase PEPCK_ATP PF01293.18 001082172.1_37924001_1 - 0.049 12.2 0.0 0.57 8.7 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase KTI12 PF08433.8 001082172.1_37924001_1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF258 PF03193.14 001082172.1_37924001_1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.4 001082172.1_37924001_1 - 0.088 12.9 0.0 0.68 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.10 001082172.1_37924001_1 - 0.16 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.16 001082172.1_37924001_1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AA_permease PF00324.19 001082649.1_37927001_1 - 4.4e-140 467.3 34.6 5.3e-140 467.1 34.6 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.13 001082649.1_37927001_1 - 2.3e-137 458.2 0.0 7e-84 282.1 0.0 2.1 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease_N PF08403.8 001082649.1_37927001_1 - 2.5e-26 90.8 0.1 6e-26 89.6 0.1 1.7 1 0 0 1 1 1 1 Amino acid permease N-terminal APS_kinase PF01583.18 001082173.1_37924001_1 - 5e-73 244.1 0.0 7.8e-73 243.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.15 001082173.1_37924001_1 - 7.6e-68 228.1 0.0 1.6e-67 227.0 0.0 1.6 2 0 0 2 2 2 1 ATP-sulfurylase PUA_2 PF14306.4 001082173.1_37924001_1 - 1.8e-51 173.8 0.0 3.5e-51 172.9 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.4 001082173.1_37924001_1 - 2.2e-05 24.5 0.0 4.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001082173.1_37924001_1 - 0.0006 20.2 0.1 0.0024 18.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain 6PF2K PF01591.16 001082173.1_37924001_1 - 0.039 13.1 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF258 PF03193.14 001082173.1_37924001_1 - 0.093 12.5 0.3 0.21 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CbiA PF01656.21 001082173.1_37924001_1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.8 001082173.1_37924001_1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.4 001082173.1_37924001_1 - 0.15 12.2 0.0 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain PEPCK_ATP PF01293.18 001082173.1_37924001_1 - 0.19 10.2 0.0 0.47 8.9 0.0 1.6 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.4 001082173.1_37924001_1 - 0.19 11.3 0.2 0.58 9.8 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sulfotransfer_1 PF00685.25 001082176.1_37923001_1 - 2.9e-77 259.6 0.0 3.7e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001082176.1_37923001_1 - 5e-11 43.3 0.0 4.5e-08 33.6 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family SRCR PF00530.16 001082177.1_37925001_2 - 2.2e-16 60.1 27.2 2.2e-08 34.4 2.2 4.1 4 0 0 4 4 4 3 Scavenger receptor cysteine-rich domain Comm PF15957.3 001082177.1_37925001_2 - 0.044 14.0 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Commissureless PX PF00787.22 001082654.1_37923001_3 - 3.4e-19 68.8 0.0 5.7e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.22 001082654.1_37923001_3 - 7.4e-18 64.1 0.1 1.8e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 PB1 domain SH3_1 PF00018.26 001082654.1_37923001_3 - 4.6e-12 45.2 0.0 1.4e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001082654.1_37923001_3 - 4.2e-11 42.2 0.0 2e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.4 001082654.1_37923001_3 - 1.2e-10 40.9 0.0 3.2e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain F420_oxidored PF03807.15 001171275.1_37923001_1 - 3.3e-16 59.5 0.0 7.2e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.17 001171275.1_37923001_1 - 1.2e-13 51.2 9.3 4.4e-13 49.3 6.3 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component 2-Hacid_dh_C PF02826.17 001171275.1_37923001_1 - 0.0035 16.6 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.13 001171275.1_37923001_1 - 0.0044 17.1 0.0 0.0074 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.18 001171275.1_37923001_1 - 0.037 14.0 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2768 PF10966.6 001171275.1_37923001_1 - 0.043 14.1 3.5 0.18 12.1 3.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) NAD_binding_7 PF13241.4 001171275.1_37923001_1 - 0.089 13.1 0.0 0.3 11.4 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding 7tm_1 PF00001.19 001082659.1_37926001_2 - 1.7e-24 86.4 3.8 3.8e-24 85.2 3.8 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1218 PF06749.10 001082659.1_37926001_2 - 1.3 9.5 6.3 3.3 8.2 0.6 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) Filament PF00038.19 001171481.1_37923001_1 - 9.1e-116 386.7 47.6 1.1e-115 386.4 47.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.12 001171481.1_37923001_1 - 6.7e-23 81.2 7.6 1.4e-22 80.2 7.6 1.6 1 0 0 1 1 1 1 Intermediate filament head (DNA binding) region Reo_sigmaC PF04582.10 001171481.1_37923001_1 - 9.2e-05 21.9 5.9 0.16 11.2 0.4 3.1 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Spc7 PF08317.9 001171481.1_37923001_1 - 0.00046 19.0 42.5 0.001 17.9 8.9 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.7 001171481.1_37923001_1 - 0.0044 17.1 39.5 0.26 11.3 8.8 4.0 1 1 3 4 4 4 2 JNK_SAPK-associated protein-1 Trimer_CC PF08954.9 001171481.1_37923001_1 - 0.03 13.7 0.2 0.03 13.7 0.2 4.1 4 0 0 4 4 3 0 Trimerisation motif DUF1664 PF07889.10 001171481.1_37923001_1 - 0.039 13.8 21.7 0.064 13.1 2.9 4.4 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.10 001171481.1_37923001_1 - 0.047 13.6 15.8 0.44 10.5 0.3 4.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.7 001171481.1_37923001_1 - 0.057 12.7 37.7 0.17 11.2 9.6 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 IncA PF04156.12 001171481.1_37923001_1 - 0.1 12.2 45.3 1.5 8.5 8.7 4.0 1 1 4 5 5 5 0 IncA protein TPR_MLP1_2 PF07926.10 001171481.1_37923001_1 - 0.11 12.4 42.1 0.56 10.1 9.7 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.16 001171481.1_37923001_1 - 0.12 12.4 24.5 0.85 9.7 0.1 6.0 7 1 0 7 7 5 0 Homeobox associated leucine zipper HMMR_N PF15905.3 001171481.1_37923001_1 - 0.12 11.7 36.7 0.13 11.6 5.7 3.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal GAS PF13851.4 001171481.1_37923001_1 - 0.15 11.2 41.3 0.012 14.9 11.3 3.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.4 001171481.1_37923001_1 - 0.2 10.8 32.2 0.63 9.2 14.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CENP-H PF05837.10 001171481.1_37923001_1 - 0.23 11.7 34.0 0.12 12.7 3.6 4.5 1 1 4 5 5 5 0 Centromere protein H (CENP-H) DUF5082 PF16888.3 001171481.1_37923001_1 - 0.32 11.2 27.8 0.7 10.1 0.2 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF5082) Mnd1 PF03962.13 001171481.1_37923001_1 - 0.53 10.0 34.6 37 4.0 20.0 3.7 1 1 2 3 3 3 0 Mnd1 family DUF573 PF04504.12 001171481.1_37923001_1 - 0.54 10.8 9.5 4.4 7.9 0.5 4.1 2 2 2 4 4 4 0 Protein of unknown function, DUF573 DUF3584 PF12128.6 001171481.1_37923001_1 - 0.59 7.4 40.1 0.56 7.5 37.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TolA_bind_tri PF16331.3 001171481.1_37923001_1 - 0.62 10.0 43.0 0.22 11.5 3.8 6.4 4 1 2 6 6 6 0 TolA binding protein trimerisation SHE3 PF17078.3 001171481.1_37923001_1 - 0.64 9.5 35.3 2.5 7.6 12.2 3.3 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 WD40_alt PF14077.4 001171481.1_37923001_1 - 0.71 9.7 10.8 33 4.3 1.5 4.8 5 0 0 5 5 4 0 Alternative WD40 repeat motif CENP-F_leu_zip PF10473.7 001171481.1_37923001_1 - 0.71 9.8 35.7 0.56 10.1 4.2 3.0 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.4 001171481.1_37923001_1 - 0.92 9.2 41.4 0.58 9.8 0.4 3.9 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH APG6 PF04111.10 001171481.1_37923001_1 - 1.1 8.4 41.7 0.05 12.8 3.4 3.3 1 1 3 4 4 4 0 Autophagy protein Apg6 bZIP_1 PF00170.19 001171481.1_37923001_1 - 1.5 8.9 22.7 7.8 6.5 1.4 5.9 4 1 2 6 6 6 0 bZIP transcription factor Fib_alpha PF08702.8 001171481.1_37923001_1 - 1.5 8.8 28.4 0.2 11.7 6.9 3.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Patched PF02460.16 001171481.1_37923001_1 - 1.9 6.3 4.4 2.6 5.9 4.4 1.1 1 0 0 1 1 1 0 Patched family Prefoldin PF02996.15 001171481.1_37923001_1 - 2.1 8.2 28.9 0.04 13.7 2.6 5.6 4 2 0 5 5 5 0 Prefoldin subunit Lectin_N PF03954.12 001171481.1_37923001_1 - 2.3 7.8 10.4 20 4.8 0.1 3.8 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain TACC PF05010.12 001171481.1_37923001_1 - 2.9 7.5 38.6 1.7 8.3 9.7 2.6 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) HR1 PF02185.14 001171481.1_37923001_1 - 3 7.9 35.3 0.6 10.1 1.1 5.1 3 2 1 4 4 4 0 Hr1 repeat UPF0184 PF03670.11 001171481.1_37923001_1 - 3.2 8.1 8.9 0.14 12.4 0.4 2.9 2 1 0 2 2 1 0 Uncharacterised protein family (UPF0184) KLRAQ PF10205.7 001171481.1_37923001_1 - 3.8 7.7 29.2 0.81 9.8 10.5 4.3 2 2 3 5 5 5 0 Predicted coiled-coil domain-containing protein DUF4200 PF13863.4 001171481.1_37923001_1 - 9.2 6.6 44.1 0.57 10.4 13.5 4.6 1 1 3 4 4 3 0 Domain of unknown function (DUF4200) Aa_trans PF01490.16 001082183.1_37925001_2 - 1.1e-76 258.1 25.6 1.4e-76 257.7 25.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SLD3 PF08639.8 001082183.1_37925001_2 - 0.26 9.8 0.4 0.38 9.3 0.4 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Ets PF00178.20 001082661.1_37923001_2 - 4e-37 126.4 1.2 7.8e-37 125.5 1.2 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.14 001082661.1_37923001_2 - 6.9e-34 115.6 0.1 1.3e-33 114.7 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain HSF_DNA-bind PF00447.15 001082661.1_37923001_2 - 0.12 12.8 0.0 0.51 10.8 0.0 2.0 2 0 0 2 2 2 0 HSF-type DNA-binding CHGN PF05679.14 001171483.1_37925001_1 - 2.9e-147 491.5 0.0 3.3e-147 491.3 0.0 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.14 001171483.1_37925001_1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Serpin PF00079.18 001082192.1_37923001_1 - 4.4e-119 398.0 0.1 5e-119 397.8 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pkinase_Tyr PF07714.15 001082688.1_37925001_1 - 2.3e-104 348.2 0.0 1.2e-103 345.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.23 001082688.1_37925001_1 - 5.7e-45 153.6 0.0 9.1e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.14 001082688.1_37925001_1 - 5.4e-37 125.6 0.0 1e-14 54.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.4 001082688.1_37925001_1 - 2e-36 124.3 0.1 1.5e-12 47.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001082688.1_37925001_1 - 2e-25 88.8 0.2 1.7e-10 41.0 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.23 001082688.1_37925001_1 - 1.3e-24 86.0 0.0 5e-09 36.1 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001082688.1_37925001_1 - 1.4e-16 60.5 1.5 0.00022 21.2 0.1 5.4 4 2 0 4 4 4 3 Immunoglobulin V-set domain Ig_5 PF16681.3 001082688.1_37925001_1 - 2.8e-07 30.7 0.0 0.069 13.5 0.0 4.0 3 2 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.10 001082688.1_37925001_1 - 0.0057 16.6 2.7 0.18 11.8 0.0 3.8 3 1 2 5 5 5 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.3 001082688.1_37925001_1 - 0.032 14.1 0.1 16 5.5 0.0 3.3 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Kinase-like PF14531.4 001082688.1_37925001_1 - 0.051 12.8 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Kinase-like MHC_I_3 PF16497.3 001082689.1_37923001_1 - 1.2e-78 263.0 0.4 1.5e-78 262.7 0.4 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.13 001082689.1_37923001_1 - 1.1e-10 41.6 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.16 001082689.1_37923001_1 - 1.7e-05 24.4 0.0 2.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_3 PF13927.4 001082689.1_37923001_1 - 0.014 15.9 0.0 0.2 12.1 0.0 2.2 1 1 1 2 2 2 0 Immunoglobulin domain ig PF00047.23 001082689.1_37923001_1 - 0.03 14.4 0.0 3.5 7.7 0.0 2.4 1 1 0 2 2 2 0 Immunoglobulin domain Nucleoside_tran PF01733.16 001082690.1_37925001_3 - 3.9e-112 374.5 3.6 5.2e-112 374.1 3.6 1.2 1 0 0 1 1 1 1 Nucleoside transporter Calsarcin PF05556.9 001082215.1_37922001_1 - 5.9e-101 336.9 0.0 6.7e-101 336.7 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) PAX PF00292.16 001082217.1_37923001_3 - 8.8e-67 222.6 1.7 2.2e-65 218.1 1.7 2.3 1 1 0 1 1 1 1 'Paired box' domain Homeobox PF00046.27 001082217.1_37923001_3 - 5.4e-23 80.4 4.5 1.1e-22 79.5 4.5 1.5 1 0 0 1 1 1 1 Homeobox domain HTH_32 PF13565.4 001082217.1_37923001_3 - 1.4e-05 25.5 1.7 0.0035 17.8 0.0 3.3 3 1 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.5 001082217.1_37923001_3 - 0.0061 16.0 0.0 0.023 14.2 0.0 1.9 2 0 0 2 2 2 1 InsA C-terminal domain Homeobox_KN PF05920.9 001082217.1_37923001_3 - 0.16 11.8 1.2 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain C1q PF00386.19 001082222.2_37922001_2 - 2.8e-39 134.1 0.8 3.5e-39 133.8 0.8 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.16 001082222.2_37922001_2 - 3e-10 39.6 31.8 8e-09 35.0 31.8 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) wnt PF00110.17 001082224.1_37923001_1 - 2.7e-106 355.4 14.2 3.2e-106 355.2 14.2 1.0 1 0 0 1 1 1 1 wnt family Ion_trans_2 PF07885.14 001082705.2_37925001_1 - 1.4e-29 101.8 21.4 1.1e-17 63.7 2.3 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.29 001082705.2_37925001_1 - 8.4e-05 21.8 6.3 0.00085 18.5 0.1 2.2 2 0 0 2 2 2 2 Ion transport protein Patched PF02460.16 001082228.1_37928001_1 - 5.3e-78 262.8 11.1 5.9e-46 156.8 0.1 2.1 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.3 001082228.1_37928001_1 - 1.3e-73 247.4 6.8 2.5e-73 246.5 6.8 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.6 001082228.1_37928001_1 - 3.3e-55 186.0 0.4 3.3e-55 186.0 0.4 2.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.13 001082228.1_37928001_1 - 9.3e-07 27.9 0.5 9.3e-07 27.9 0.5 2.6 3 0 0 3 3 3 1 MMPL family Tad PF13400.4 001082228.1_37928001_1 - 0.12 12.6 0.1 0.12 12.6 0.1 5.1 5 0 0 5 5 5 0 Putative Flp pilus-assembly TadE/G-like ACR_tran PF00873.17 001082228.1_37928001_1 - 1.3 6.4 11.6 2.4 5.6 11.6 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Glyco_tranf_2_3 PF13641.4 001082709.1_37924001_1 - 1.5e-24 87.0 0.1 4.3e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.13 001082709.1_37924001_1 - 8.7e-18 64.1 3.6 3.4e-12 45.7 0.1 3.4 2 1 1 3 3 3 3 Chitin synthase Glyco_trans_2_3 PF13632.4 001082709.1_37924001_1 - 9.7e-13 48.3 4.3 9.7e-13 48.3 4.3 2.3 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.24 001082709.1_37924001_1 - 1.3e-08 34.8 0.0 0.0051 16.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.4 001082709.1_37924001_1 - 1.9e-05 24.1 0.0 4.3e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF1294 PF06961.11 001082709.1_37924001_1 - 0.054 13.6 0.6 0.15 12.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1294) Uteroglobin PF01099.15 001082723.1_37921001_3 - 8.7e-21 73.8 2.2 1.2e-20 73.4 2.2 1.2 1 0 0 1 1 1 1 Uteroglobin family Sulfotransfer_1 PF00685.25 001082725.1_37923001_3 - 2.9e-81 272.7 0.0 2.9e-81 272.7 0.0 1.5 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001082725.1_37923001_3 - 3.1e-08 34.1 0.0 3e-05 24.4 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Metallophos PF00149.26 001082727.1_37927001_1 - 4.6e-37 128.4 0.0 6.7e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Caldesmon PF02029.13 001082256.2_37929001_2 - 9.5e-183 608.3 88.5 9.5e-183 608.3 88.5 2.0 2 0 0 2 2 2 1 Caldesmon Herpes_capsid PF06112.9 104121.1_26225120_1 - 4.3 7.2 7.8 0.49 10.3 0.8 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Tmemb_185A PF10269.7 104121.1_26225120_2 - 1.3e-17 64.3 7.8 1.9e-17 63.7 7.8 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein TT_ORF2 PF02957.13 104121.1_26225120_3 - 0.93 10.3 2.9 1.7 9.4 2.9 1.4 1 0 0 1 1 1 0 TT viral ORF2 Ribosomal_L16 PF00252.16 001244967.1_49823001_3 - 1.3e-31 109.2 0.0 1.8e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S21 PF01165.18 001266914.2_29621001_2 - 6.7e-18 64.0 0.5 6.7e-18 64.0 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S21 Circo_capsid PF02443.13 001266914.2_29621001_2 - 0.38 10.2 4.8 0.53 9.7 4.8 1.2 1 0 0 1 1 1 0 Circovirus capsid protein Ribosomal_L24e PF01246.18 001258062.1_29623001_2 - 3.6e-33 113.5 7.1 6.7e-33 112.6 7.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Ribosomal_L27A PF00828.17 001243528.1_49823001_1 - 7e-28 97.6 0.0 1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_S8 PF00410.17 001285101.1_29521001_2 - 2.4e-22 79.1 0.0 3.4e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L13 PF00572.16 001283875.1_29525001_3 - 2.5e-44 150.4 0.0 3.4e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L13 PF00572.16 001243415.1_49822001_1 - 3.9e-46 156.2 0.0 5e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Tuberculin PF12198.6 001261499.1_29622001_1 - 0.11 12.5 0.7 0.19 11.7 0.7 1.4 1 0 0 1 1 1 0 Theoretical tuberculin protein L51_S25_CI-B8 PF05047.14 001261499.1_29622001_2 - 7.4e-16 57.7 0.1 1e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ribosomal_L27A PF00828.17 001193567.1_29622001_3 - 2.3e-24 86.3 0.1 3e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MRP-L51 PF10244.7 001194316.1_29622001_3 - 6.7e-35 119.0 0.5 9.1e-35 118.6 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit L51_S25_CI-B8 PF05047.14 001257670.1_29623001_1 - 1.2e-10 41.0 0.2 2.3e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ribosomal_L16 PF00252.16 001266431.1_29623001_3 - 8.7e-30 103.3 0.0 1.2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e 4F5 PF04419.12 001252527.1_39726001_1 - 5.1e-09 36.7 17.3 9.7e-09 35.8 17.3 1.5 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.5 001252527.1_39726001_1 - 0.00069 19.8 0.4 0.0017 18.5 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001252527.1_39726001_1 - 0.08 13.1 1.5 0.14 12.4 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ribosomal_L44 PF00935.17 001252527.1_39726001_1 - 0.31 11.4 3.5 0.61 10.5 3.5 1.4 1 0 0 1 1 1 0 Ribosomal protein L44 SRF-TF PF00319.16 001205195.1_39723001_1 - 4.1e-23 80.5 0.3 5.8e-23 80.0 0.3 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Rib_recp_KP_reg PF05104.10 001252040.1_39721001_1 - 1.1 10.1 10.4 1.4 9.8 10.4 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Metallothio PF00131.18 001252040.1_39721001_3 - 4.6e-19 68.2 63.9 5.7e-19 67.9 63.9 1.1 1 0 0 1 1 1 1 Metallothionein Brix PF04427.16 001204428.2_39724001_2 - 6.8e-44 150.1 0.2 9.7e-44 149.6 0.2 1.2 1 0 0 1 1 1 1 Brix domain COX7a PF02238.13 001243849.1_39722001_1 - 2.3e-10 40.6 0.1 7.8e-10 38.9 0.0 1.9 3 0 0 3 3 3 1 Cytochrome c oxidase subunit VII Tox-WTIP PF15654.4 001243849.1_39722001_1 - 0.034 14.0 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif MHC_II_beta PF00969.17 001134342.2_39725001_1 - 9.6e-26 89.6 0.2 1.5e-25 89.0 0.2 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001134342.2_39725001_1 - 3e-22 78.8 0.1 4.6e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001134342.2_39725001_1 - 1.1e-07 32.2 0.3 2.3e-07 31.2 0.3 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001134342.2_39725001_1 - 1.2e-06 28.6 0.1 2.3e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001134342.2_39725001_1 - 0.0038 17.1 0.1 0.0072 16.2 0.1 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.14 001134342.2_39725001_1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ribosomal_S8 PF00410.17 001251992.2_39721001_1 - 3.1e-22 78.7 0.0 4.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 UQ_con PF00179.24 001205077.2_39725001_1 - 6.2e-17 61.4 0.0 9.5e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PIG-Y PF15159.4 001270957.1_39723001_3 - 1.6e-17 63.9 3.0 2.6e-17 63.2 3.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Trm112p PF03966.14 001270957.1_39723001_3 - 1.8e-07 31.5 0.0 4.2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Trm112p-like protein Abhydrolase_2 PF02230.14 001252028.2_39724001_1 - 2.8e-88 295.2 0.0 3.5e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.6 001252028.2_39724001_1 - 4.5e-05 22.7 0.0 0.046 12.9 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.11 001252028.2_39724001_1 - 0.0001 22.1 0.1 0.00072 19.3 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.18 001252028.2_39724001_1 - 0.00025 20.6 0.7 0.0042 16.6 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.16 001252028.2_39724001_1 - 0.00077 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.19 001252028.2_39724001_1 - 0.0021 17.4 0.0 0.14 11.5 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family Cutinase PF01083.20 001252028.2_39724001_1 - 0.007 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Cutinase FSH1 PF03959.11 001252028.2_39724001_1 - 0.016 14.7 0.0 0.098 12.2 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2974 PF11187.6 001252028.2_39724001_1 - 0.05 13.0 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ig PF00047.23 001194933.1_39723001_1 - 1.1e-24 86.3 0.0 5e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 001194933.1_39723001_1 - 3.8e-15 55.9 0.0 2.6e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001194933.1_39723001_1 - 5.4e-10 39.6 0.0 8e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001194933.1_39723001_1 - 2.9e-06 27.3 0.0 0.48 10.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin V-set domain RIIa PF02197.15 001159766.1_39721001_1 - 1.9e-05 24.1 0.1 3.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF3937 PF13073.4 001159766.1_39721001_1 - 0.033 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) Keratin_B2_2 PF13885.4 001247982.1_39723001_2 - 1.3e-39 133.8 330.7 6.5e-08 32.3 51.8 6.6 2 2 4 6 6 6 6 Keratin, high sulfur B2 protein Keratin_B2 PF01500.15 001247982.1_39723001_2 - 8.6e-11 42.0 252.9 0.0057 16.5 67.0 5.8 1 1 6 7 7 7 6 Keratin, high sulfur B2 protein Pkinase_Tyr PF07714.15 001204797.1_39727001_3 - 7.5e-58 195.7 0.0 2.7e-57 193.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.5 001204797.1_39727001_3 - 3e-55 184.6 8.0 9.8e-14 51.6 0.6 6.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001204797.1_39727001_3 - 5e-50 167.1 28.8 2.1e-11 44.0 0.3 8.7 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.28 001204797.1_39727001_3 - 3.6e-48 159.9 28.2 1.1e-06 28.7 0.0 11.2 12 0 0 12 12 11 8 Ankyrin repeat Pkinase PF00069.23 001204797.1_39727001_3 - 6.8e-46 156.6 0.0 1.5e-45 155.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.4 001204797.1_39727001_3 - 1.2e-40 132.7 15.4 0.00038 20.6 0.0 11.6 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.4 001204797.1_39727001_3 - 2.9e-38 129.2 9.0 7.2e-09 35.6 0.1 9.0 2 1 8 10 10 10 8 Ankyrin repeats (many copies) APH PF01636.21 001204797.1_39727001_3 - 0.053 13.3 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.4 001204797.1_39727001_3 - 0.057 12.6 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.12 001204797.1_39727001_3 - 0.064 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001204797.1_39727001_3 - 0.069 12.6 1.5 0.16 11.4 0.1 2.1 2 0 0 2 2 2 0 RIO1 family zf-rbx1 PF12678.5 001252557.2_39725001_3 - 3.6e-20 71.9 17.2 3.6e-20 71.9 17.2 2.5 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.5 001252557.2_39725001_3 - 3.6e-15 55.6 16.8 3.6e-15 55.6 16.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.4 001252557.2_39725001_3 - 3e-06 27.2 12.9 3e-06 27.2 12.9 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.4 001252557.2_39725001_3 - 0.006 16.3 12.0 0.006 16.3 12.0 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001252557.2_39725001_3 - 0.079 12.7 15.6 0.25 11.1 15.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S3_C PF00189.18 001251999.1_39722001_1 - 2.8e-23 82.1 0.9 1e-22 80.3 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.15 001251999.1_39722001_1 - 2.1e-11 43.3 0.1 3.4e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-H2C2_2 PF13465.4 001243856.1_39726001_1 - 1.2e-102 332.0 87.5 8.8e-10 38.5 0.6 14.1 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.24 001243856.1_39726001_1 - 7.7e-71 230.7 99.9 4.6e-07 29.8 1.6 13.5 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001243856.1_39726001_1 - 5.9e-40 132.3 102.8 0.0011 19.4 0.8 13.9 14 0 0 14 14 13 13 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001243856.1_39726001_1 - 6e-29 99.3 81.3 0.00079 19.2 0.2 13.6 13 0 0 13 13 13 12 C2H2-type zinc finger KRAB PF01352.25 001243856.1_39726001_1 - 5.4e-23 80.3 0.2 1e-22 79.3 0.2 1.5 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001243856.1_39726001_1 - 5.3e-19 67.9 54.0 0.0026 17.7 1.3 9.1 5 1 5 10 10 10 10 Zinc ribbon domain zf-C2H2_jaz PF12171.6 001243856.1_39726001_1 - 1.2e-12 47.6 66.0 0.0031 17.7 0.1 13.3 14 0 0 14 14 14 7 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001243856.1_39726001_1 - 1.3e-11 43.8 86.5 0.00086 18.9 1.2 13.2 13 0 0 13 13 13 8 zinc-finger C2H2-type XPA_N PF01286.16 001243856.1_39726001_1 - 1.7e-09 37.4 56.2 1.2 9.1 0.3 13.3 13 0 0 13 13 13 4 XPA protein N-terminal zinc_ribbon_15 PF17032.3 001243856.1_39726001_1 - 5.9e-07 30.0 53.3 0.07 13.8 1.8 7.0 1 1 5 7 7 7 7 zinc-ribbon family zf-trcl PF13451.4 001243856.1_39726001_1 - 1.5e-05 24.6 52.5 1.1 9.0 0.1 12.3 11 2 0 11 11 11 2 Probable zinc-ribbon domain DUF3268 PF11672.6 001243856.1_39726001_1 - 0.00011 22.3 40.2 0.15 12.2 2.7 6.8 6 1 0 6 6 6 3 zinc-finger-containing domain FYVE PF01363.19 001243856.1_39726001_1 - 0.008 16.2 67.0 5.7 7.0 8.4 8.1 1 1 3 4 4 3 1 FYVE zinc finger C1_4 PF07975.10 001243856.1_39726001_1 - 2.3 8.4 59.4 0.97 9.6 2.2 8.3 3 2 4 9 9 9 0 TFIIH C1-like domain BolA PF01722.16 001243856.1_39726001_1 - 7.9 6.7 21.1 21 5.4 0.5 6.0 6 1 0 6 6 6 0 BolA-like protein Taxilin PF09728.7 001251862.1_39728001_3 - 6.1e-103 344.2 74.8 8.8e-103 343.6 74.8 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF3627 PF12299.6 001251862.1_39728001_3 - 1.2 9.2 12.1 0.1 12.6 5.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3627) FlaC_arch PF05377.9 001251862.1_39728001_3 - 1.6 9.0 14.2 8.2 6.8 0.6 4.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Adap_comp_sub PF00928.19 001204825.2_39729001_3 - 4.6e-64 216.2 0.7 6.4e-64 215.7 0.7 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Chromo_shadow PF01393.17 001252558.2_39725001_2 - 1.2e-32 111.6 0.1 7.8e-30 102.6 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.22 001252558.2_39725001_2 - 3.1e-20 71.7 0.3 3e-17 62.1 0.4 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.4 001252558.2_39725001_2 - 0.016 15.2 0.2 0.051 13.6 0.2 1.8 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Ribosomal_S17 PF00366.18 001251972.1_39722001_2 - 3.5e-18 65.4 0.0 6.4e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4661 PF15576.4 001244703.2_39724001_1 - 2.4e-132 440.3 3.2 2.4e-132 440.3 3.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4661) V1R PF03402.12 001167543.1_39722001_1 - 2e-57 194.7 27.4 2.4e-57 194.4 27.4 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167543.1_39722001_1 - 7.8e-06 25.1 33.8 9.1e-06 24.9 33.8 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) I-set PF07679.14 001173481.2_39729001_1 - 6.5e-164 532.4 0.0 1.1e-21 76.5 0.0 10.1 10 0 0 10 10 10 9 Immunoglobulin I-set domain Pkinase PF00069.23 001173481.2_39729001_1 - 7.9e-110 366.2 0.0 2.9e-55 187.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.4 001173481.2_39729001_1 - 5.3e-97 318.4 0.0 7.7e-11 42.3 0.0 10.2 11 0 0 11 11 9 9 Immunoglobulin domain Ig_2 PF13895.4 001173481.2_39729001_1 - 9.2e-59 195.6 0.0 8.4e-07 29.1 0.0 9.5 9 0 0 9 9 9 9 Immunoglobulin domain Pkinase_Tyr PF07714.15 001173481.2_39729001_1 - 4.4e-51 173.5 0.0 4.8e-27 94.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase ig PF00047.23 001173481.2_39729001_1 - 9.4e-49 163.4 0.0 3.1e-05 23.9 0.0 10.8 10 1 0 10 10 10 9 Immunoglobulin domain SPEG_u2 PF16650.3 001173481.2_39729001_1 - 2.4e-32 110.8 14.4 1.7e-31 108.1 14.4 2.7 1 0 0 1 1 1 1 Unstructured region on SPEG complex protein V-set PF07686.15 001173481.2_39729001_1 - 5.6e-16 58.5 0.8 0.04 14.0 0.0 10.7 9 4 0 9 9 9 2 Immunoglobulin V-set domain C2-set_2 PF08205.10 001173481.2_39729001_1 - 2.7e-13 49.7 1.1 3.4 7.7 0.0 8.3 9 0 0 9 9 8 2 CD80-like C2-set immunoglobulin domain fn3 PF00041.19 001173481.2_39729001_1 - 9.4e-09 35.4 0.2 0.0057 16.8 0.1 2.7 2 0 0 2 2 2 2 Fibronectin type III domain Izumo-Ig PF16706.3 001173481.2_39729001_1 - 3.7e-05 23.6 2.2 1.1 9.2 0.1 6.6 8 0 0 8 8 8 1 Izumo-like Immunoglobulin domain Kdo PF06293.12 001173481.2_39729001_1 - 0.0024 17.1 0.3 0.02 14.1 0.1 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001173481.2_39729001_1 - 0.01 15.6 2.4 0.42 10.4 0.0 3.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Receptor_2B4 PF11465.6 001173481.2_39729001_1 - 0.019 15.0 0.0 8.5 6.5 0.0 4.5 6 0 0 6 6 4 0 Natural killer cell receptor 2B4 Kinase-like PF14531.4 001173481.2_39729001_1 - 0.029 13.5 0.0 0.095 11.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like DUF4198 PF10670.7 001173481.2_39729001_1 - 0.083 13.1 0.0 12 6.1 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4198) Herpes_gE PF02480.14 001173481.2_39729001_1 - 0.094 11.3 0.0 18 3.8 0.0 4.1 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein E Pox_ser-thr_kin PF05445.9 001173481.2_39729001_1 - 0.11 11.3 0.0 12 4.6 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.7 001173481.2_39729001_1 - 0.25 10.7 0.0 0.95 8.8 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DSL PF01414.17 001173481.2_39729001_1 - 2.5 8.2 4.4 29 4.8 0.9 3.2 2 0 0 2 2 2 0 Delta serrate ligand V1R PF03402.12 001167546.1_39722001_1 - 1.4e-57 195.2 27.1 1.6e-57 195.0 27.1 1.0 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R TAS2R PF05296.11 001167546.1_39722001_1 - 1e-07 31.2 32.7 1.2e-07 31.0 32.7 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Sedlin_N PF04628.11 001167546.1_39722001_1 - 0.0083 16.1 0.1 0.018 15.0 0.1 1.6 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SelR PF01641.16 001114751.1_39723001_3 - 1.3e-17 63.8 0.6 2e-17 63.3 0.6 1.2 1 0 0 1 1 1 1 SelR domain NDUFB10 PF10249.7 001204758.1_29622001_2 - 1.9e-48 164.0 14.1 2.3e-48 163.7 14.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 CiPC PF15800.3 001130933.1_39523001_1 - 5.3e-112 374.8 4.9 6.6e-112 374.5 4.9 1.1 1 0 0 1 1 1 1 Clock interacting protein circadian REV PF00424.16 001130933.1_39523001_3 - 0.011 15.7 0.4 0.02 14.7 0.4 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Ras PF00071.20 001127285.1_39522001_1 - 2.3e-50 170.2 0.0 2.7e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001127285.1_39522001_1 - 1.7e-21 76.6 0.0 4.2e-21 75.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001127285.1_39522001_1 - 1e-07 31.5 0.0 1.6e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001127285.1_39522001_1 - 0.0067 15.7 0.0 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit NACHT PF05729.10 001127285.1_39522001_1 - 0.011 15.6 0.8 1.2 8.9 0.3 2.7 2 1 1 3 3 3 0 NACHT domain MMR_HSR1 PF01926.21 001127285.1_39522001_1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.25 001127285.1_39522001_1 - 0.035 14.5 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.14 001127285.1_39522001_1 - 0.049 13.4 0.0 8.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.4 001127285.1_39522001_1 - 0.074 13.3 0.9 0.16 12.2 0.9 1.8 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.20 001127285.1_39522001_1 - 0.095 11.6 0.8 2.8 6.8 0.4 2.1 1 1 1 2 2 2 0 NB-ARC domain AAA_22 PF13401.4 001127285.1_39522001_1 - 0.11 12.7 0.7 1.3 9.2 0.2 2.6 1 1 1 2 2 2 0 AAA domain LEAP-2 PF07359.9 001168764.1_40421001_1 - 5.5e-44 147.7 3.3 6.1e-44 147.6 3.3 1.0 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EB PF01683.16 001168764.1_40421001_1 - 0.0015 18.6 0.1 0.0015 18.6 0.1 1.1 1 0 0 1 1 1 1 EB module Ras PF00071.20 001123190.1_49822001_1 - 1.4e-49 167.6 0.0 1.7e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001123190.1_49822001_1 - 4.9e-21 75.0 0.0 9.2e-21 74.2 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001123190.1_49822001_1 - 5.5e-07 29.1 0.0 9e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001123190.1_49822001_1 - 0.0057 16.0 0.1 0.015 14.6 0.0 1.7 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit NACHT PF05729.10 001123190.1_49822001_1 - 0.0069 16.2 0.9 1.2 8.9 0.3 2.8 2 1 1 3 3 3 1 NACHT domain MMR_HSR1 PF01926.21 001123190.1_49822001_1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.25 001123190.1_49822001_1 - 0.04 14.3 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.4 001123190.1_49822001_1 - 0.13 12.5 0.6 0.19 12.0 0.6 1.7 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.20 001123190.1_49822001_1 - 0.17 10.8 0.5 4 6.2 0.4 2.1 1 1 1 2 2 2 0 NB-ARC domain CiPC PF15800.3 001265895.1_29626001_1 - 9.8e-114 380.5 12.8 1.2e-113 380.2 12.8 1.1 1 0 0 1 1 1 1 Clock interacting protein circadian RNA_pol_A_bac PF01000.24 001258119.1_29626001_3 - 2.7e-39 133.8 0.0 4.5e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.22 001258119.1_29626001_3 - 2.6e-14 52.3 0.0 4.4e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_Rpb2_6 PF00562.26 001261497.1_29629001_3 - 6.4e-128 427.0 0.2 9e-128 426.5 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.13 001261497.1_29629001_3 - 4.8e-68 228.5 0.1 8.9e-68 227.7 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.12 001261497.1_29629001_3 - 4.6e-56 189.3 0.0 1.2e-55 188.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.18 001261497.1_29629001_3 - 2.5e-34 117.4 0.2 9.6e-34 115.5 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.11 001261497.1_29629001_3 - 2.9e-24 85.0 0.8 6.9e-24 83.8 0.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.14 001261497.1_29629001_3 - 9.4e-24 83.2 0.0 2.1e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.15 001261497.1_29629001_3 - 6.5e-19 68.1 1.3 1.5e-18 66.9 1.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Amidoligase_2 PF12224.6 001261497.1_29629001_3 - 0.028 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme DNA_pol_E_B PF04042.14 001267008.1_29625001_2 - 1.1e-45 155.5 0.2 1.5e-45 155.0 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.8 001267008.1_29625001_2 - 1.7e-10 41.2 0.0 2.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal S1 PF00575.21 001141955.1_39522001_3 - 2.2e-20 72.6 0.1 3.7e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.15 001141955.1_39522001_3 - 2.2e-13 50.2 0.0 3.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.10 001141955.1_39522001_3 - 0.00013 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Arrestin_N PF00339.27 001173086.1_09924001_3 - 1.6e-37 128.7 0.1 6.7e-34 116.9 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 001173086.1_09924001_3 - 3.3e-22 79.2 0.7 4.9e-22 78.6 0.7 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Transglut_C PF00927.20 001173086.1_09924001_3 - 0.026 14.5 0.6 0.053 13.5 0.6 1.4 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain TFIIS_C PF01096.16 001171411.1_37921001_1 - 5.6e-21 74.0 6.4 5.6e-21 74.0 6.4 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.14 001171411.1_37921001_1 - 1.6e-08 34.2 1.3 1.6e-08 34.2 1.3 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.6 001171411.1_37921001_1 - 0.017 14.7 0.7 0.044 13.3 0.7 1.8 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Nudix_N_2 PF14803.4 001171411.1_37921001_1 - 0.02 14.6 5.6 0.02 14.6 5.6 3.2 3 0 0 3 3 3 0 Nudix N-terminal zf-SAP30 PF13866.4 001171411.1_37921001_1 - 0.022 14.7 0.1 0.061 13.2 0.1 1.7 2 0 0 2 2 2 0 SAP30 zinc-finger Lar_restr_allev PF14354.4 001171411.1_37921001_1 - 0.077 13.3 11.0 0.46 10.8 1.1 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.5 001171411.1_37921001_1 - 0.9 9.4 15.8 0.5 10.2 5.0 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.4 001171411.1_37921001_1 - 3 8.3 8.7 0.15 12.5 0.9 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain ABC1 PF03109.14 001265945.1_29624001_2 - 4.3e-32 110.6 0.0 6.6e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family BTG PF07742.10 001142887.1_39523001_3 - 1.7e-42 143.8 0.0 2.3e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 BTG family LRR_8 PF13855.4 001257870.1_29625001_1 - 8.9e-23 79.7 16.4 1.5e-13 50.1 2.2 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 001257870.1_29625001_1 - 4.4e-14 52.2 25.1 6.2e-05 23.1 4.1 4.7 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) I-set PF07679.14 001257870.1_29625001_1 - 8.7e-06 25.6 0.3 1.4e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.4 001257870.1_29625001_1 - 7.2e-05 22.2 6.3 0.00054 19.4 2.6 2.3 1 1 2 3 3 3 3 Leucine-rich repeat V-set PF07686.15 001257870.1_29625001_1 - 0.0001 22.3 0.2 0.00023 21.1 0.2 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001257870.1_29625001_1 - 0.00011 22.6 0.1 0.00022 21.6 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001257870.1_29625001_1 - 0.00036 20.5 0.2 0.00067 19.6 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.4 001257870.1_29625001_1 - 0.00037 20.3 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) Ig_2 PF13895.4 001257870.1_29625001_1 - 0.008 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.3 001257870.1_29625001_1 - 0.014 15.3 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain LRR_1 PF00560.31 001257870.1_29625001_1 - 0.095 13.1 28.4 2 9.1 1.3 7.2 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.4 001257870.1_29625001_1 - 2.1 8.5 19.7 0.84 9.7 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich repeat BTG PF07742.10 001266234.1_29622001_3 - 1e-41 141.3 0.0 1.3e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 BTG family BTG PF07742.10 001246212.1_39523001_3 - 2.2e-42 143.5 0.1 4e-42 142.6 0.1 1.5 1 0 0 1 1 1 1 BTG family Spc7 PF08317.9 001244631.1_49827001_2 - 0.00029 19.7 48.6 0.065 12.0 0.2 4.7 2 2 2 4 4 4 4 Spc7 kinetochore protein IncA PF04156.12 001244631.1_49827001_2 - 0.00032 20.4 57.5 0.073 12.7 15.7 4.8 2 1 3 5 5 5 4 IncA protein TPR_MLP1_2 PF07926.10 001244631.1_49827001_2 - 0.0013 18.7 1.1 0.0013 18.7 1.1 5.9 4 3 1 5 5 5 1 TPR/MLP1/MLP2-like protein MscS_porin PF12795.5 001244631.1_49827001_2 - 0.0045 16.4 14.0 0.0045 16.4 14.0 4.5 3 2 1 4 4 4 2 Mechanosensitive ion channel porin domain Syntaxin-6_N PF09177.9 001244631.1_49827001_2 - 0.0094 16.4 32.2 0.051 14.0 1.1 5.4 2 2 3 5 5 5 3 Syntaxin 6, N-terminal Reo_sigmaC PF04582.10 001244631.1_49827001_2 - 0.012 14.9 24.2 0.33 10.2 2.2 4.4 1 1 1 4 4 4 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.10 001244631.1_49827001_2 - 0.17 11.8 23.2 0.098 12.6 2.6 5.0 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.8 001244631.1_49827001_2 - 0.19 11.8 33.4 2.2 8.3 2.0 5.4 2 2 2 5 5 5 0 Fibrinogen alpha/beta chain family DUF211 PF02680.12 001244631.1_49827001_2 - 0.28 11.2 2.1 0.98 9.5 2.1 1.9 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Fez1 PF06818.13 001244631.1_49827001_2 - 0.33 11.2 42.6 2.2 8.5 0.6 4.0 1 1 4 5 5 5 0 Fez1 COG2 PF06148.9 001244631.1_49827001_2 - 0.36 10.8 37.2 0.25 11.3 1.9 6.1 3 2 3 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF713 PF05218.12 001244631.1_49827001_2 - 0.42 10.2 19.7 0.17 11.5 9.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF713) ADIP PF11559.6 001244631.1_49827001_2 - 0.48 10.4 43.8 0.066 13.2 6.2 5.6 3 2 2 6 6 6 0 Afadin- and alpha -actinin-Binding DUF2746 PF10874.6 001244631.1_49827001_2 - 0.5 10.6 6.4 0.97 9.7 0.6 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF2746) DUF1664 PF07889.10 001244631.1_49827001_2 - 0.55 10.1 34.5 12 5.8 0.0 6.9 4 1 3 7 7 7 0 Protein of unknown function (DUF1664) TMPIT PF07851.11 001244631.1_49827001_2 - 0.58 9.2 27.5 0.33 10.0 2.5 4.0 3 1 2 5 5 5 0 TMPIT-like protein WEMBL PF05701.9 001244631.1_49827001_2 - 0.62 8.5 44.9 0.44 9.0 36.8 2.7 2 2 0 2 2 2 0 Weak chloroplast movement under blue light FPP PF05911.9 001244631.1_49827001_2 - 0.63 8.1 33.2 1.3 7.1 0.5 2.8 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4407 PF14362.4 001244631.1_49827001_2 - 0.74 9.0 33.2 0.62 9.2 12.0 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) ERM PF00769.17 001244631.1_49827001_2 - 1 9.0 44.7 0.013 15.2 16.6 3.5 1 1 2 3 3 3 0 Ezrin/radixin/moesin family WD40_alt PF14077.4 001244631.1_49827001_2 - 1.2 9.0 3.4 2.2 8.1 0.2 3.2 3 0 0 3 3 2 0 Alternative WD40 repeat motif DUF4988 PF16378.3 001244631.1_49827001_2 - 1.8 8.0 7.9 9.1 5.7 0.0 3.4 3 1 1 4 4 3 0 Domain of unknown function COG5 PF10392.7 001244631.1_49827001_2 - 1.9 8.6 26.4 2.8 8.0 2.3 5.4 3 2 1 4 4 4 0 Golgi transport complex subunit 5 DUF724 PF05266.12 001244631.1_49827001_2 - 4.8 6.8 31.1 0.43 10.2 0.8 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF724) Transket_pyr PF02779.22 001123219.1_49823001_1 - 1e-44 152.2 0.0 1.4e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 001123219.1_49823001_1 - 2.4e-35 121.0 0.0 5.2e-35 119.9 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.2 001123219.1_49823001_1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II C1q PF00386.19 001244286.1_49823001_1 - 3.1e-36 124.2 0.5 3.9e-36 123.9 0.5 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.16 001244286.1_49823001_1 - 6.3e-14 51.3 55.2 1.4e-08 34.2 25.7 2.6 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) BCL_N PF04714.11 001265776.2_29622001_3 - 5e-27 93.6 7.7 7.9e-27 92.9 7.7 1.3 1 0 0 1 1 1 1 BCL7, N-terminal conserver region FXMRP1_C_core PF12235.6 001265776.2_29622001_3 - 0.47 11.0 6.3 0.5 10.9 1.7 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal BTG PF07742.10 001099936.1_49824001_1 - 2.7e-42 143.2 0.0 3.6e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 BTG family A_deamin PF02137.16 001161795.2_39727001_1 - 4.7e-109 364.6 0.0 6.2e-109 364.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.24 001161795.2_39727001_1 - 1.1e-27 96.4 0.0 1.1e-13 51.5 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.5 001161795.2_39727001_1 - 0.14 12.3 1.1 2.2 8.5 0.1 3.0 2 2 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 C1q PF00386.19 001265799.1_29625001_3 - 9.3e-37 125.9 0.1 1.2e-36 125.5 0.1 1.2 1 0 0 1 1 1 1 C1q domain Collagen PF01391.16 001265799.1_29625001_3 - 4.5e-09 35.8 28.7 4.5e-09 35.8 28.7 2.6 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) DAP PF15228.4 001283767.1_29524001_1 - 3.7e-18 66.3 4.5 3.7e-18 66.3 4.5 2.8 3 0 0 3 3 3 2 Death-associated protein DAP PF15228.4 001283767.1_29524001_2 - 8.1e-16 58.8 0.0 2.6e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 Death-associated protein C1q PF00386.19 001078676.1_49822001_1 - 4.9e-34 117.1 0.2 6e-34 116.9 0.2 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.16 001078676.1_49822001_1 - 1.1e-08 34.6 31.5 2.3e-08 33.5 31.5 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) SH3_9 PF14604.4 001132276.1_43529001_1 - 4.3e-43 144.8 2.8 3.4e-14 52.3 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.26 001132276.1_43529001_1 - 2e-39 132.8 5.8 3.2e-14 52.1 0.2 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.15 001132276.1_43529001_1 - 2.1e-35 120.0 4.2 2.3e-13 49.5 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain Filament PF00038.19 001132276.1_43529001_1 - 0.064 12.7 3.5 0.1 12.0 3.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein betaPIX_CC PF16523.3 001132276.1_43529001_1 - 0.24 11.1 2.5 0.54 10.0 2.5 1.6 1 0 0 1 1 1 0 betaPIX coiled coil A_deamin PF02137.16 001161793.2_39728001_1 - 1.1e-107 360.1 0.0 1.5e-107 359.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.24 001161793.2_39728001_1 - 1.2e-27 96.2 0.0 1.2e-13 51.4 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.5 001161793.2_39728001_1 - 0.14 12.3 1.0 2.3 8.4 0.1 3.0 2 2 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 BTG PF07742.10 001246210.1_39526001_1 - 2.5e-40 136.8 0.0 3.8e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 BTG family SH3_9 PF14604.4 001266309.1_29629001_1 - 5.5e-44 147.7 2.9 4.1e-14 52.0 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.26 001266309.1_29629001_1 - 8.8e-40 133.9 6.3 3.8e-14 51.9 0.2 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.15 001266309.1_29629001_1 - 3.8e-36 122.4 4.0 2.8e-13 49.2 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain Filament PF00038.19 001266309.1_29629001_1 - 0.012 15.0 4.0 0.019 14.4 4.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein A_deamin PF02137.16 001161794.2_39729001_1 - 8.2e-113 377.0 0.0 1.1e-112 376.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.24 001161794.2_39729001_1 - 6.4e-27 93.9 0.0 2.7e-13 50.3 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif BCL_N PF04714.11 001194509.1_29623001_1 - 4.4e-28 97.0 6.6 8.9e-28 96.0 6.6 1.5 1 0 0 1 1 1 1 BCL7, N-terminal conserver region A_deamin PF02137.16 001128632.3_39729001_1 - 3.4e-114 381.6 0.0 4.4e-114 381.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.24 001128632.3_39729001_1 - 6.1e-27 94.0 0.0 2.6e-13 50.3 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif PARP PF00644.18 001145978.2_32929001_3 - 1.4e-47 161.9 0.0 2.3e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain VIT PF08487.8 001145978.2_32929001_3 - 2.6e-45 153.1 0.1 5.3e-45 152.1 0.1 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Drf_FH1 PF06346.10 001145978.2_32929001_3 - 1.2e-21 76.8 215.5 4.7e-13 48.9 78.9 3.9 2 1 2 4 4 3 3 Formin Homology Region 1 VIT_2 PF13757.4 001145978.2_32929001_3 - 1.1e-15 57.1 0.0 3.4e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.4 001145978.2_32929001_3 - 3e-14 53.1 0.0 6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.26 001145978.2_32929001_3 - 3.2e-11 43.7 0.0 5.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain BRCT_2 PF16589.3 001145978.2_32929001_3 - 8.5e-11 42.0 0.5 2.8e-10 40.3 0.1 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.24 001145978.2_32929001_3 - 1.1e-08 35.2 1.4 5e-08 33.1 0.1 2.8 3 0 0 3 3 2 1 BRCA1 C Terminus (BRCT) domain VWA_2 PF13519.4 001145978.2_32929001_3 - 2.9e-07 31.0 0.0 7.2e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain PTCB-BRCT PF12738.5 001145978.2_32929001_3 - 0.00067 19.4 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain PARP_reg PF02877.12 001145978.2_32929001_3 - 0.074 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain NTP_transf_2 PF01909.21 001261299.1_29628001_2 - 2.9e-17 62.6 0.0 5.5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.17 001261299.1_29628001_2 - 1.4e-15 57.1 0.0 2.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase ThrE PF06738.10 001109294.1_45725001_2 - 0.007 15.6 0.9 0.011 14.9 0.9 1.3 1 0 0 1 1 1 1 Putative threonine/serine exporter Collagen PF01391.16 001105288.1_49829001_3 - 2.2e-159 517.2 660.7 1.8e-08 33.9 24.1 22.3 3 2 15 18 18 18 13 Collagen triple helix repeat (20 copies) COLFI PF01410.16 001105288.1_49829001_3 - 4e-86 288.0 0.0 5e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.22 001105288.1_49829001_3 - 0.0003 21.2 0.0 0.00056 20.4 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.4 001105288.1_49829001_3 - 0.0025 17.9 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.21 001105288.1_49829001_3 - 0.039 14.0 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain DNA_pol_E_B PF04042.14 001266293.1_29624001_1 - 2.9e-49 167.1 0.1 6.5e-49 166.0 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DPM2 PF07297.10 001260828.2_29622001_2 - 4.8e-31 106.8 5.9 6.9e-31 106.2 5.9 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.10 001260828.2_29622001_2 - 0.013 15.3 2.9 0.018 14.8 2.9 1.2 1 0 0 1 1 1 0 PIG-P DNA_pol_E_B PF04042.14 001244996.1_49824001_3 - 3.5e-48 163.6 0.0 6.2e-48 162.8 0.0 1.4 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Sedlin_N PF04628.11 001265756.1_29622001_3 - 7.6e-35 119.8 0.9 9.2e-35 119.5 0.9 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.10 001265756.1_29622001_3 - 8.3e-10 38.6 0.2 1e-09 38.3 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family HAD_2 PF13419.4 001106146.1_45723001_1 - 8.1e-24 84.5 0.0 9.8e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.24 001106146.1_45723001_1 - 3.5e-13 50.2 0.0 1.1e-11 45.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.4 001106146.1_45723001_1 - 0.00038 20.4 0.0 0.081 12.9 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.5 001106146.1_45723001_1 - 0.051 13.8 0.1 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4385 PF14328.4 001194363.1_29623001_3 - 0.18 11.7 0.2 0.58 10.1 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4385) zf-H2C2_2 PF13465.4 001171358.1_37925001_1 - 3.9e-25 87.0 55.7 1.4e-07 31.5 0.8 7.9 8 1 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.24 001171358.1_37925001_1 - 1.5e-18 66.0 65.5 7.5e-05 22.8 2.2 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001171358.1_37925001_1 - 4.4e-16 58.0 62.7 0.00088 19.8 1.6 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger zf-met PF12874.5 001171358.1_37925001_1 - 8.4e-10 38.6 41.8 0.00064 19.9 1.4 7.5 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001171358.1_37925001_1 - 0.00081 19.5 50.1 0.04 14.1 0.2 7.9 7 1 1 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.4 001171358.1_37925001_1 - 0.003 17.1 1.2 0.003 17.1 1.2 6.2 6 0 0 6 6 6 3 C2H2-type zinc-finger domain Mu-like_Com PF10122.7 001171358.1_37925001_1 - 0.11 11.8 5.7 0.089 12.1 3.1 2.3 2 1 0 2 2 2 0 Mu-like prophage protein Com PyrI_C PF02748.13 001171358.1_37925001_1 - 0.15 11.8 0.2 0.15 11.8 0.2 5.0 6 1 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Glyco_transf_6 PF03414.11 001194925.2_39723001_2 - 3.2e-166 551.8 0.0 3.7e-166 551.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 6 Abhydrolase_1 PF00561.18 001243485.1_49823001_1 - 8.1e-26 91.1 0.0 3.5e-19 69.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001243485.1_49823001_1 - 8.5e-16 59.1 0.1 1.4e-15 58.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.6 001243485.1_49823001_1 - 5.9e-15 55.1 0.0 3.5e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.9 001243485.1_49823001_1 - 0.0005 19.9 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.11 001243485.1_49823001_1 - 0.0018 17.8 0.0 0.015 14.8 0.1 2.2 3 0 0 3 3 3 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.19 001243485.1_49823001_1 - 0.016 14.5 0.1 0.46 9.8 0.1 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family LIP PF03583.12 001243485.1_49823001_1 - 0.021 14.0 0.2 0.23 10.6 0.1 2.1 2 0 0 2 2 2 0 Secretory lipase DLH PF01738.16 001243485.1_49823001_1 - 0.03 13.7 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.14 001243485.1_49823001_1 - 0.11 12.1 0.0 7.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.8 001243485.1_49823001_1 - 0.12 12.3 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein C2-set_2 PF08205.10 001123218.1_49823001_3 - 8.4e-26 89.8 4.5 1.9e-20 72.6 0.0 3.9 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.4 001123218.1_49823001_3 - 8.2e-24 83.9 0.1 2.7e-12 47.0 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001123218.1_49823001_3 - 1.3e-23 83.0 0.0 5.2e-14 52.2 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.23 001123218.1_49823001_3 - 1.7e-21 76.0 0.1 4.1e-11 42.8 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.14 001123218.1_49823001_3 - 4.4e-15 55.4 0.0 4.5e-07 29.7 0.0 3.9 3 1 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.15 001123218.1_49823001_3 - 8.7e-09 35.4 0.2 0.21 11.6 0.0 4.1 2 2 1 3 3 3 3 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001123218.1_49823001_3 - 2.5e-05 24.1 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.3 001123218.1_49823001_3 - 0.0001 22.4 0.0 0.036 14.3 0.0 2.6 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.13 001123218.1_49823001_3 - 0.0019 18.2 0.0 0.051 13.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin C2-set domain CcmD PF04995.12 001123218.1_49823001_3 - 0.031 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) ICAM_N PF03921.12 001123218.1_49823001_3 - 0.07 12.7 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain PP2C PF00481.19 001244067.1_49825001_3 - 4e-39 134.7 0.0 5.2e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C HLH PF00010.24 001194245.1_29622001_3 - 5.2e-17 61.4 0.7 7.6e-17 60.9 0.7 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CARD PF00619.19 001134572.1_45722001_1 - 9.4e-05 22.2 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Caspase recruitment domain zf-DHHC PF01529.18 001260892.1_29627001_3 - 6.4e-35 120.0 21.2 6.4e-35 120.0 21.2 2.1 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.5 001260892.1_29627001_3 - 9.3e-31 106.1 0.2 3.5e-16 59.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001260892.1_29627001_3 - 1.7e-29 101.7 6.9 1.4e-08 35.0 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.4 001260892.1_29627001_3 - 6.9e-27 90.4 2.2 0.00011 22.2 0.1 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.4 001260892.1_29627001_3 - 1.1e-24 86.0 3.8 6.9e-06 26.2 0.3 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.28 001260892.1_29627001_3 - 1.5e-21 75.7 3.7 1.1e-05 25.6 0.4 5.8 5 0 0 5 5 5 5 Ankyrin repeat PH PF00169.27 001174057.1_49822001_3 - 0.094 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 PH domain AAA PF00004.27 001267001.1_29625001_3 - 1.2e-40 138.8 0.0 2.2e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.8 001267001.1_29625001_3 - 6.3e-28 96.4 0.1 1.9e-27 94.9 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.16 001267001.1_29625001_3 - 5.3e-24 83.9 8.4 1.1e-23 82.9 8.4 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain IstB_IS21 PF01695.15 001267001.1_29625001_3 - 1.8e-05 24.5 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.11 001267001.1_29625001_3 - 2e-05 23.6 0.0 3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.4 001267001.1_29625001_3 - 3.8e-05 23.9 0.1 0.0043 17.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.4 001267001.1_29625001_3 - 5.4e-05 23.5 0.2 0.006 16.8 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.4 001267001.1_29625001_3 - 0.00016 21.6 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.10 001267001.1_29625001_3 - 0.00018 20.7 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.12 001267001.1_29625001_3 - 0.00023 21.0 0.0 0.00059 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.11 001267001.1_29625001_3 - 0.00089 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.4 001267001.1_29625001_3 - 0.0011 18.5 0.1 1.8 7.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.4 001267001.1_29625001_3 - 0.0014 19.0 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.12 001267001.1_29625001_3 - 0.0025 17.8 0.0 0.0062 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.4 001267001.1_29625001_3 - 0.004 17.2 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.20 001267001.1_29625001_3 - 0.022 15.0 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.4 001267001.1_29625001_3 - 0.036 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.14 001267001.1_29625001_3 - 0.049 13.0 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.4 001267001.1_29625001_3 - 0.053 13.8 0.0 0.32 11.3 0.0 2.3 3 0 0 3 3 2 0 AAA domain ATPase PF06745.11 001267001.1_29625001_3 - 0.053 12.7 0.1 5.8 6.0 0.0 2.3 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.19 001267001.1_29625001_3 - 0.068 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.10 001267001.1_29625001_3 - 0.095 12.5 0.0 0.44 10.3 0.0 2.1 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.24 001267001.1_29625001_3 - 0.18 11.4 0.0 0.43 10.1 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain YhdB PF14148.4 001267001.1_29625001_3 - 0.25 11.3 1.1 0.47 10.5 1.1 1.4 1 0 0 1 1 1 0 YhdB-like protein TPR_2 PF07719.15 001267001.1_29625001_3 - 1.2 9.3 5.2 0.48 10.5 1.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat CDI PF02234.17 001278937.1_32322001_1 - 4.4e-20 71.5 0.9 8.8e-20 70.5 0.9 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Peptidase_M16_M PF16187.3 001258074.1_29629001_2 - 2.5e-106 354.9 6.1 4.5e-106 354.1 6.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.18 001258074.1_29629001_2 - 8.3e-48 162.0 0.1 2.7e-46 157.1 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001258074.1_29629001_2 - 1.6e-38 132.5 0.4 1.1e-22 80.8 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Tn916-Xis PF09035.8 001258074.1_29629001_2 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Excisionase from transposon Tn916 Cylicin_N PF15241.4 001284111.1_29525001_2 - 5.7e-48 161.4 6.1 5.7e-48 161.4 6.1 6.0 5 3 1 7 7 7 1 Cylicin N-terminus Serpin PF00079.18 001280707.1_39523001_1 - 1.2e-131 439.3 0.0 1.3e-131 439.2 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) HPS3_C PF14763.4 001098588.1_49827001_3 - 6.1e-179 594.7 2.0 9.7e-179 594.1 2.0 1.3 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, C-terminal HPS3_Mid PF14762.4 001098588.1_49827001_3 - 6.7e-176 584.6 7.6 9.2e-176 584.2 7.6 1.2 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.4 001098588.1_49827001_3 - 3.5e-71 239.0 0.1 6.8e-71 238.1 0.1 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 PDZ PF00595.22 001137639.1_49825001_2 - 7.1e-33 112.7 0.0 4e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) EBP50_C PF09007.9 001137639.1_49825001_2 - 7.5e-29 101.2 3.2 5.5e-18 66.1 1.0 2.4 1 1 1 2 2 2 2 EBP50, C-terminal PDZ_2 PF13180.4 001137639.1_49825001_2 - 3.1e-14 52.9 0.1 1.2e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain EMI PF07546.11 001194009.1_29622001_1 - 3e-18 66.2 3.5 3e-18 66.2 3.5 2.0 2 1 0 2 2 2 1 EMI domain EGF_CA PF07645.13 001194009.1_29622001_1 - 1.7e-08 34.4 7.0 1.7e-08 34.4 7.0 3.4 3 1 1 4 4 4 1 Calcium-binding EGF domain EGF_2 PF07974.11 001194009.1_29622001_1 - 1.3e-05 25.3 14.9 1.3e-05 25.3 14.9 3.6 3 0 0 3 3 3 1 EGF-like domain FXa_inhibition PF14670.4 001194009.1_29622001_1 - 2.1e-05 24.6 8.3 2.1e-05 24.6 8.3 3.4 2 1 1 3 3 3 1 Coagulation Factor Xa inhibitory site cEGF PF12662.5 001194009.1_29622001_1 - 7.4e-05 22.5 6.8 0.00056 19.6 0.4 3.9 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.25 001194009.1_29622001_1 - 0.00091 19.4 10.0 0.00091 19.4 10.0 4.2 5 1 0 5 5 5 2 EGF-like domain hEGF PF12661.5 001194009.1_29622001_1 - 0.0026 18.3 8.1 0.0026 18.3 8.1 4.8 6 0 0 6 6 6 2 Human growth factor-like EGF SlyX PF04102.10 001194009.1_29622001_1 - 0.099 13.1 0.3 12 6.5 0.1 2.2 2 0 0 2 2 2 0 SlyX Trimer_CC PF08954.9 001194009.1_29622001_1 - 0.1 12.0 3.6 0.16 11.4 1.9 2.0 2 0 0 2 2 2 0 Trimerisation motif DUF4988 PF16378.3 001194009.1_29622001_1 - 0.17 11.3 0.0 43 3.5 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function Mu-like_Pro PF10123.7 001194009.1_29622001_2 - 0.21 10.9 0.0 0.21 10.9 0.0 1.5 2 0 0 2 2 2 0 Mu-like prophage I protein UQ_con PF00179.24 001194433.2_29627001_3 - 5.7e-52 175.0 0.1 8e-52 174.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001194433.2_29627001_3 - 0.026 14.7 0.1 0.046 13.9 0.1 1.3 1 0 0 1 1 1 0 RWD domain ABC_membrane PF00664.21 001242747.1_37625001_1 - 5.5e-54 183.5 0.7 8.1e-54 183.0 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.25 001242747.1_37625001_1 - 7e-35 120.4 0.0 2.7e-34 118.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.17 001242747.1_37625001_1 - 0.00014 21.2 0.1 0.22 10.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.4 001242747.1_37625001_1 - 0.00017 21.1 0.1 0.00044 19.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.4 001242747.1_37625001_1 - 0.00063 19.9 0.8 0.0073 16.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.4 001242747.1_37625001_1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.4 001242747.1_37625001_1 - 0.0052 16.2 1.7 0.068 12.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.4 001242747.1_37625001_1 - 0.006 17.0 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.4 001242747.1_37625001_1 - 0.033 13.7 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.4 001242747.1_37625001_1 - 0.052 13.8 2.5 0.053 13.8 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.4 001242747.1_37625001_1 - 0.062 12.9 6.5 0.39 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.14 001242747.1_37625001_1 - 0.093 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UNC-50 PF05216.11 001195448.1_29622001_3 - 1.4e-89 299.3 19.5 1.6e-89 299.1 19.5 1.0 1 0 0 1 1 1 1 UNC-50 family COX14 PF14880.4 001195448.1_29622001_3 - 0.11 12.2 1.2 0.91 9.3 0.1 2.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly BTB PF00651.29 001261341.2_29624001_3 - 1.8e-23 82.7 0.0 3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BEN PF10523.7 001261341.2_29624001_3 - 1.1e-09 38.2 0.1 2.5e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 BEN domain Pro_isomerase PF00160.19 001193973.1_29622001_2 - 2.2e-47 161.1 0.1 2.6e-47 160.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Abhydrolase_1 PF00561.18 001123134.1_49823001_1 - 4.2e-36 124.8 1.0 5e-36 124.5 1.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.14 001123134.1_49823001_1 - 8.5e-26 89.2 0.0 1.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.6 001123134.1_49823001_1 - 1.3e-05 24.5 0.0 4.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.18 001123134.1_49823001_1 - 0.029 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.5 001123134.1_49823001_1 - 0.041 14.4 0.0 0.063 13.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family EF-hand_1 PF00036.30 001098558.1_39723001_3 - 2.3e-41 136.1 9.6 1.7e-09 36.4 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001098558.1_39723001_3 - 2.5e-35 120.6 2.7 3.2e-18 65.8 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001098558.1_39723001_3 - 6.1e-33 112.2 9.6 5.9e-15 54.6 0.3 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001098558.1_39723001_3 - 3.9e-29 97.9 5.7 4.4e-09 35.4 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001098558.1_39723001_3 - 8.7e-26 88.1 6.9 3.5e-06 26.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001098558.1_39723001_3 - 2.4e-14 53.3 0.2 1.4e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001098558.1_39723001_3 - 6.9e-09 35.5 0.2 0.00032 20.5 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001098558.1_39723001_3 - 7.7e-07 29.3 0.0 0.024 14.8 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001098558.1_39723001_3 - 5.9e-05 23.7 0.0 0.0064 17.2 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.8 001098558.1_39723001_3 - 0.00018 21.4 0.7 0.00047 20.0 0.1 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.11 001098558.1_39723001_3 - 0.00036 20.4 0.0 0.17 11.8 0.0 2.8 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) DUF1103 PF06513.9 001098558.1_39723001_3 - 0.0081 15.7 1.6 0.011 15.2 1.6 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF4497 PF14924.4 001098558.1_39723001_3 - 0.009 16.3 0.0 4.6 7.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) Caleosin PF05042.11 001098558.1_39723001_3 - 0.033 14.0 0.3 2.2 8.0 0.0 3.0 1 1 3 4 4 4 0 Caleosin related protein DUF3349 PF11829.6 001098558.1_39723001_3 - 0.034 14.8 0.4 6.6 7.5 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.14 001098558.1_39723001_3 - 0.046 13.9 0.2 6.3 7.0 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 TerB PF05099.11 001098558.1_39723001_3 - 0.057 13.3 0.4 3.9 7.3 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB GPHH PF16905.3 001098558.1_39723001_3 - 0.12 12.1 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated DUF2267 PF10025.7 001098558.1_39723001_3 - 0.14 12.3 0.0 0.36 11.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) SurA_N_2 PF13623.4 001098558.1_39723001_3 - 0.15 11.7 0.8 2.4 7.9 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EphA2_TM PF14575.4 001168905.1_40421001_1 - 0.029 15.0 0.0 0.033 14.9 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.13 001168905.1_40421001_1 - 0.099 12.3 3.1 0.19 11.4 3.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Adeno_E3 PF06040.9 001168905.1_40421001_1 - 0.18 11.9 2.1 0.32 11.0 2.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 protein Tweety PF04906.11 001168905.1_40421001_1 - 0.19 10.2 1.5 0.24 9.9 1.5 1.1 1 0 0 1 1 1 0 Tweety 7tm_1 PF00001.19 001001624.1_49823001_3 - 2.3e-46 158.1 37.8 4.3e-46 157.2 37.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001624.1_49823001_3 - 7.6e-07 28.6 32.3 1.7e-06 27.5 32.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF621 PF04789.13 001001624.1_49823001_3 - 0.011 14.8 27.0 0.015 14.3 27.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Pkinase_Tyr PF07714.15 001266263.1_29628001_3 - 1.1e-36 126.3 0.0 1.6e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001266263.1_29628001_3 - 1.6e-35 122.7 0.0 2.4e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.10 001266263.1_29628001_3 - 3.1e-15 55.2 0.9 6.3e-15 54.2 0.9 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.21 001266263.1_29628001_3 - 8.5e-13 49.1 11.3 2.6e-12 47.5 11.3 1.9 1 0 0 1 1 1 1 Activin types I and II receptor domain FTA2 PF13095.4 001266263.1_29628001_3 - 0.029 13.9 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.20 001260878.1_29625001_1 - 5.1e-31 106.2 0.1 2.4e-15 56.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.9 001260878.1_29625001_1 - 1.7e-05 24.6 0.1 0.0013 18.6 0.0 2.8 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.4 001260878.1_29625001_1 - 0.028 13.9 0.0 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001260878.1_29625001_1 - 0.067 13.0 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DbpA PF03880.13 001260878.1_29625001_1 - 0.092 12.6 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Metaviral_G PF09595.8 001260878.1_29625001_2 - 0.38 10.7 3.1 2.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Metaviral_G glycoprotein Glyco_transf_64 PF09258.8 001243549.1_49824001_3 - 8.8e-84 280.5 0.0 1.1e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.4 001243549.1_49824001_3 - 0.027 14.2 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF1049 PF06305.9 001243549.1_49824001_3 - 0.17 11.6 0.5 0.39 10.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Glycos_transf_2 PF00535.24 001243549.1_49824001_3 - 0.18 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF1387 PF07139.9 001177916.1_49825001_2 - 1.7e-124 415.4 12.1 1.7e-124 415.4 12.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1387) DUF1296 PF06972.9 001177916.1_49825001_2 - 0.17 11.9 3.3 0.077 13.0 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1296) fn3 PF00041.19 001244329.1_49826001_1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Apolipoprotein PF01442.16 001244329.1_49826001_1 - 0.46 10.3 5.0 0.69 9.7 5.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HET-S PF17108.3 001244329.1_49826001_3 - 0.18 11.4 1.3 0.37 10.5 1.3 1.5 1 0 0 1 1 1 0 N-terminal small S protein of HET, non-prionic Filament PF00038.19 001244622.1_49824001_1 - 3.1e-100 335.6 14.5 4e-100 335.3 14.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.10 001244622.1_49824001_1 - 0.057 13.3 23.3 0.11 12.4 0.9 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein OprB PF04966.10 001244622.1_49824001_1 - 0.19 11.0 1.8 4.9 6.3 0.2 2.4 1 1 1 2 2 2 0 Carbohydrate-selective porin, OprB family Lectin_N PF03954.12 001244622.1_49824001_1 - 1.3 8.7 6.5 3.9 7.1 1.0 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain V_ATPase_I PF01496.17 001244622.1_49824001_1 - 1.6 6.4 5.9 0.74 7.5 3.2 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.4 001244622.1_49824001_1 - 1.7 8.5 7.0 5.3 6.9 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) Phage_Mu_Gam PF07352.10 001244622.1_49824001_1 - 1.9 8.2 15.9 0.86 9.3 1.1 3.7 4 0 0 4 4 4 0 Bacteriophage Mu Gam like protein Mod_r PF07200.11 001244622.1_49824001_1 - 2.7 8.0 19.6 9.7 6.2 0.0 3.9 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein FlxA PF14282.4 001244622.1_49824001_1 - 3 7.8 16.2 0.44 10.4 5.5 3.6 2 1 1 3 3 3 0 FlxA-like protein IncA PF04156.12 001244622.1_49824001_1 - 4 7.1 21.1 89 2.7 0.0 4.0 2 1 1 3 3 3 0 IncA protein Atg14 PF10186.7 001244622.1_49824001_1 - 5.5 5.8 12.6 4.6 6.1 9.0 2.2 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bacillus_HBL PF05791.9 001244622.1_49824001_1 - 5.9 6.4 12.0 0.12 12.0 2.2 2.9 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.10 001244622.1_49824001_1 - 7.6 6.4 15.4 0.41 10.5 0.3 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) SlyX PF04102.10 001244622.1_49824001_1 - 8.8 6.9 15.0 83 3.8 0.0 4.9 4 1 2 6 6 6 0 SlyX End3 PF12761.5 001244622.1_49824001_1 - 9 6.3 9.3 4.5 7.3 6.0 2.2 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Guanylate_kin PF00625.19 001261360.1_29629001_2 - 7.5e-46 156.0 0.1 1.1e-45 155.4 0.1 1.2 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.6 001261360.1_29629001_2 - 4e-21 74.7 6.1 6.7e-21 74.0 6.1 1.4 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.26 001261360.1_29629001_2 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.4 001261360.1_29629001_2 - 0.081 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.23 001266169.1_29625001_2 - 1.5e-74 250.6 0.0 2.2e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.8 001266169.1_29625001_2 - 1.4e-59 199.7 0.0 2.5e-59 198.9 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.15 001266169.1_29625001_2 - 1.7e-34 119.2 0.0 3.4e-34 118.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase SnoaL_3 PF13474.4 001266169.1_29625001_2 - 2.1e-10 40.8 0.0 4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.4 001266169.1_29625001_2 - 9.5e-10 38.7 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) APH PF01636.21 001266169.1_29625001_2 - 0.0046 16.8 0.1 1.1 8.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.12 001266169.1_29625001_2 - 0.0088 15.3 0.6 0.016 14.4 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL_2 PF12680.5 001266169.1_29625001_2 - 0.035 14.6 0.0 0.072 13.6 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain FTA2 PF13095.4 001266169.1_29625001_2 - 0.11 12.0 0.1 6 6.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.20 001266169.1_29625001_2 - 0.13 11.8 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family HCO3_cotransp PF00955.19 001173030.1_09927001_1 - 1.8e-231 769.3 6.5 2.3e-231 769.0 6.5 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.11 001173030.1_09927001_1 - 9e-100 333.8 1.6 1.8e-99 332.8 0.1 2.2 2 0 0 2 2 2 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.20 001173030.1_09927001_1 - 0.00064 19.5 0.0 0.0055 16.5 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Fmp27_WPPW PF10359.7 001173030.1_09927001_1 - 0.045 12.5 0.0 0.045 12.5 0.0 2.0 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain SH3_9 PF14604.4 001266744.2_29626001_3 - 3.5e-10 39.4 0.0 7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001266744.2_29626001_3 - 4.1e-05 22.9 0.0 8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain RBD-FIP PF09457.8 001168822.1_40423001_1 - 3.2e-21 74.8 1.3 3.2e-21 74.8 1.3 4.6 4 1 0 4 4 4 1 FIP domain WD40_alt PF14077.4 001168822.1_40423001_1 - 0.0083 15.8 0.3 0.0083 15.8 0.3 3.5 3 0 0 3 3 3 1 Alternative WD40 repeat motif ZapB PF06005.10 001168822.1_40423001_1 - 0.0084 16.4 3.1 0.0084 16.4 3.1 4.7 2 1 1 4 4 4 3 Cell division protein ZapB DivIC PF04977.13 001168822.1_40423001_1 - 0.029 14.0 2.1 0.029 14.0 2.1 5.6 5 1 1 6 6 6 0 Septum formation initiator HAP1_N PF04849.11 001168822.1_40423001_1 - 0.63 9.1 51.7 0.16 11.0 37.5 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Jnk-SapK_ap_N PF09744.7 001168822.1_40423001_1 - 1.1 9.3 53.1 0.24 11.5 17.0 4.0 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.19 001168822.1_40423001_1 - 1.2 9.1 36.7 0.059 13.3 2.3 5.2 3 2 3 6 6 6 0 bZIP transcription factor HALZ PF02183.16 001168822.1_40423001_1 - 3.3 7.9 34.3 0.092 12.8 7.0 5.2 4 1 1 5 5 5 0 Homeobox associated leucine zipper HAUS-augmin3 PF14932.4 001168822.1_40423001_1 - 4.3 6.7 40.2 1.2 8.4 25.9 3.0 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Fez1 PF06818.13 001168822.1_40423001_1 - 4.9 7.4 41.6 0.26 11.6 24.5 2.3 1 1 1 2 2 2 0 Fez1 Carb_anhydrase PF00194.19 001173075.1_09923001_3 - 8e-90 300.7 0.0 9.7e-90 300.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase NAP PF00956.16 001194874.1_29629001_3 - 4e-24 85.1 0.1 1.7e-21 76.4 0.0 2.5 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Lipoprotein_7 PF01540.14 001194874.1_29629001_3 - 0.1 11.7 1.2 0.15 11.2 1.2 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Cluap1 PF10234.7 001194874.1_29629001_3 - 0.15 11.3 0.4 0.21 10.8 0.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Ion_trans PF00520.29 001261485.1_29624001_1 - 1.8e-39 135.3 10.8 2.3e-39 135.0 10.8 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001261485.1_29624001_1 - 9.9e-21 73.8 0.0 1.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001261485.1_29624001_1 - 3.1e-11 43.0 4.9 3.1e-11 43.0 4.9 2.1 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.24 001261485.1_29624001_1 - 1.7 8.4 4.6 1.2 8.9 0.3 2.4 1 1 2 3 3 3 0 Ligand-gated ion channel PHD_4 PF16866.3 001266388.1_29629001_1 - 1e-21 76.6 12.9 5e-21 74.5 12.9 2.3 1 0 0 1 1 1 1 PHD-finger zf-CXXC PF02008.18 001266388.1_29629001_1 - 1.3e-12 47.4 20.8 1.3e-12 47.4 20.8 2.7 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.31 001266388.1_29629001_1 - 6.7e-09 35.3 4.9 6.7e-09 35.3 4.9 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.5 001266388.1_29629001_1 - 3.2e-08 33.2 6.7 7.9e-08 31.9 6.7 1.7 1 0 0 1 1 1 1 F-box-like JmjC PF02373.20 001266388.1_29629001_1 - 9e-06 26.0 0.7 0.00015 22.1 0.7 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.4 001266388.1_29629001_1 - 0.013 15.2 0.1 0.064 12.9 0.1 1.9 1 1 0 1 1 1 0 Cupin-like domain LRR_6 PF13516.4 001266388.1_29629001_1 - 0.051 13.5 3.9 27 5.0 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Cupin_1 PF00190.20 001266388.1_29629001_1 - 0.19 11.2 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Cupin EGF PF00008.25 001257469.1_29625001_2 - 0.00021 21.4 4.3 0.00062 19.9 4.3 1.9 1 0 0 1 1 1 1 EGF-like domain CSD PF00313.20 001256768.1_39522001_2 - 1e-16 60.4 0.1 2.3e-16 59.3 0.1 1.6 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.21 001256768.1_39522001_2 - 8.3e-05 22.4 2.7 8.3e-05 22.4 2.7 2.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.4 001256768.1_39522001_2 - 1.6 8.3 14.3 0.64 9.6 1.8 2.5 2 0 0 2 2 2 0 Zinc knuckle Serpin PF00079.18 001266017.2_29623001_2 - 6.1e-120 400.8 3.7 7e-120 400.6 3.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Ferritin PF00210.22 001283240.1_29522001_1 - 0.00038 20.3 0.1 0.00052 19.8 0.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain Ferritin PF00210.22 001283240.1_29522001_3 - 7.6e-17 61.4 0.5 9.8e-17 61.1 0.5 1.1 1 0 0 1 1 1 1 Ferritin-like domain Snapin_Pallidin PF14712.4 001257650.1_29622001_2 - 4.6e-27 94.2 2.4 6e-27 93.8 2.4 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Laminin_II PF06009.10 001257650.1_29622001_2 - 0.011 15.7 2.6 0.015 15.2 2.6 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF507 PF04368.11 001257650.1_29622001_2 - 0.017 14.9 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF507) IRK PF01007.18 001173397.1_09923001_1 - 9.8e-130 432.2 1.9 1.2e-129 431.9 1.9 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.14 001173397.1_09923001_1 - 5.5e-05 22.9 3.1 0.00012 21.8 3.1 1.7 1 0 0 1 1 1 1 Ion channel DUF1180 PF06679.10 001257710.2_29623001_1 - 8.8 6.6 6.7 16 5.8 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TFIIA PF03153.11 001257710.2_29623001_2 - 7.1e-91 306.1 71.3 3.8e-53 181.9 23.1 2.3 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.12 001257710.2_29623001_2 - 0.98 8.6 11.5 0.02 14.2 4.4 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Neur_chan_memb PF02932.14 001257710.2_29623001_2 - 1 9.2 6.1 0.18 11.7 0.6 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Mito_carr PF00153.25 001164510.1_49824001_1 - 3.6e-73 241.4 2.8 1e-24 86.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.4 001164510.1_49824001_1 - 1.1e-21 76.9 3.0 7.3e-11 42.3 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001164510.1_49824001_1 - 9.8e-18 62.2 2.7 0.00024 20.3 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001164510.1_49824001_1 - 1e-15 56.1 5.0 0.00031 20.3 0.2 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001164510.1_49824001_1 - 2.8e-10 39.1 2.7 0.0021 17.4 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.4 001164510.1_49824001_1 - 9.6e-10 38.0 3.7 5.1e-05 22.8 0.1 3.6 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001164510.1_49824001_1 - 1e-05 25.7 0.1 0.011 15.9 0.2 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001164510.1_49824001_1 - 3.8e-05 23.5 0.7 0.0011 18.8 0.0 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.4 001164510.1_49824001_1 - 0.0013 18.4 0.9 1.7 8.5 0.0 3.6 2 1 1 3 3 3 2 EF hand EF-hand_9 PF14658.4 001164510.1_49824001_1 - 0.0016 18.6 0.1 1.6 9.0 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain DUF2624 PF11116.6 001164510.1_49824001_1 - 0.055 14.2 0.0 0.12 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DUF1002 PF06207.9 001164510.1_49824001_1 - 0.18 11.2 0.2 0.3 10.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Cu2_monooxygen PF01082.18 001169071.1_40424001_1 - 2.4e-49 166.8 0.6 4.2e-49 166.0 0.6 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.13 001169071.1_40424001_1 - 9.1e-46 155.1 0.0 2.3e-45 153.8 0.0 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.15 001169071.1_40424001_1 - 1.4e-32 112.4 0.2 2.5e-32 111.6 0.2 1.4 1 0 0 1 1 1 1 DOMON domain HD PF01966.20 001271642.1_29624001_1 - 5.2e-18 65.3 0.0 1.7e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 HD domain SAM_1 PF00536.28 001271642.1_29624001_1 - 9.6e-09 35.4 0.0 2.5e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 001271642.1_29624001_1 - 1.4e-08 34.6 0.0 2.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001271642.1_29624001_1 - 0.0084 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ste50p-SAM PF09235.8 001271642.1_29624001_1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Varsurf_PPLC PF03490.11 001260577.1_29623001_3 - 0.0044 16.8 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C Cpn60_TCP1 PF00118.22 001265751.1_29624001_1 - 9.3e-160 532.3 3.2 1.1e-159 532.1 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vps26 PF03643.13 001257941.1_29626001_1 - 1.1e-133 444.4 5.1 1.3e-133 444.0 5.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.27 001257941.1_29626001_1 - 0.095 12.6 0.1 1.1 9.2 0.0 2.6 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain CK_II_beta PF01214.16 001257688.1_29622001_2 - 1.4e-86 288.9 0.0 1.6e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CCDC24 PF15669.3 001257688.1_29622001_2 - 0.084 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Serpin PF00079.18 001169070.1_40423001_1 - 3.6e-130 434.5 0.4 4e-130 434.3 0.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RNA_pol_Rpb1_4 PF05000.15 001169070.1_40423001_1 - 0.11 12.3 0.1 0.33 10.8 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Mis12 PF05859.10 001194189.1_29625001_3 - 1.7e-27 96.0 1.0 2.7e-27 95.3 1.0 1.3 1 0 0 1 1 1 1 Mis12 protein WD40 PF00400.30 001283894.1_29524001_3 - 7.1e-49 162.6 5.9 1.4e-06 28.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001283894.1_29524001_3 - 2.1e-13 50.2 0.1 0.023 14.9 0.0 5.7 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001283894.1_29524001_3 - 2e-07 30.9 0.3 0.028 14.1 0.1 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001283894.1_29524001_3 - 3.7e-05 22.7 0.0 5.1 5.8 0.0 4.4 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.6 001283894.1_29524001_3 - 0.014 13.9 4.9 6.1 5.2 0.0 4.0 1 1 3 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.3 001283894.1_29524001_3 - 0.023 13.9 0.0 0.73 9.0 0.0 2.5 2 1 0 2 2 2 0 WD40-like domain RHIM PF12721.5 001130428.1_29625001_1 - 2.6e-13 50.1 7.0 2.6e-13 50.1 7.0 3.9 2 1 0 2 2 2 1 RIP homotypic interaction motif TIR_2 PF13676.4 001130428.1_29625001_1 - 0.034 14.3 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 TIR domain Ras PF00071.20 001009723.1_39526001_2 - 4.8e-10 39.1 0.0 6.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Ras family BTB PF00651.29 001009723.1_39526001_3 - 2.5e-16 59.7 0.3 0.00029 20.9 0.0 3.6 4 0 0 4 4 4 3 BTB/POZ domain zf-RING_4 PF14570.4 001009723.1_39526001_3 - 3.6 7.3 8.2 0.52 9.9 3.5 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Cir_N PF10197.7 001168875.1_40422001_1 - 9.8e-08 31.9 8.8 9.8e-08 31.9 8.8 4.2 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR adh_short PF00106.23 001261171.1_29622001_1 - 1.9e-47 161.2 1.1 2.2e-47 160.9 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001261171.1_29622001_1 - 5.3e-41 140.6 0.1 6.6e-41 140.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001261171.1_29622001_1 - 2.5e-12 46.9 2.3 4.9e-12 46.0 2.3 1.4 1 1 0 1 1 1 1 KR domain Axin_b-cat_bind PF08833.8 001261171.1_29622001_3 - 0.039 13.9 1.8 0.056 13.4 0.4 2.1 2 0 0 2 2 2 0 Axin beta-catenin binding domain Dynein_IC2 PF11540.6 001261589.1_29626001_1 - 1e-15 57.2 0.6 2.2e-15 56.1 0.6 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.30 001261589.1_29626001_1 - 1.4e-05 25.6 12.0 0.19 12.6 0.6 7.0 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001261589.1_29626001_1 - 0.004 17.3 0.0 0.048 13.8 0.0 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4329 PF14220.4 001261589.1_29626001_1 - 0.15 11.9 0.4 20 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) Pkinase PF00069.23 001194763.1_29626001_1 - 2e-72 243.6 0.0 3.3e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001194763.1_29626001_1 - 8.4e-35 120.2 0.0 1.5e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001194763.1_29626001_1 - 7.6e-06 25.3 0.0 1.3e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.12 001194763.1_29626001_1 - 0.00074 18.8 0.4 0.0014 17.8 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.9 001194763.1_29626001_1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_M60 PF13402.4 001193948.1_29626001_1 - 3.7e-99 332.2 0.0 5.3e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like Pkinase PF00069.23 001257788.1_29629001_3 - 1.3e-73 247.5 0.0 1.9e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.5 001257788.1_29629001_3 - 8.1e-51 170.4 7.0 3.7e-16 59.3 0.2 4.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001257788.1_29629001_3 - 6.1e-43 144.5 8.8 6.6e-09 36.0 0.1 7.5 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.4 001257788.1_29629001_3 - 4.7e-42 141.2 15.1 1.5e-09 37.8 0.1 8.1 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.4 001257788.1_29629001_3 - 5.3e-36 118.4 12.0 0.00028 21.0 0.1 9.1 8 0 0 8 8 8 8 Ankyrin repeat Pkinase_Tyr PF07714.15 001257788.1_29629001_3 - 1.2e-35 123.0 0.0 1.9e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.28 001257788.1_29629001_3 - 2.6e-35 119.2 12.1 1.8e-06 28.0 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat Death PF00531.20 001257788.1_29629001_3 - 5.1e-21 74.5 0.1 3.9e-20 71.7 0.0 2.6 3 0 0 3 3 2 1 Death domain COR PF16095.3 001257788.1_29629001_3 - 5.4e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Kdo PF06293.12 001257788.1_29629001_3 - 3.7e-06 26.3 0.0 7.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001257788.1_29629001_3 - 5.5e-05 22.7 0.1 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family AAA_23 PF13476.4 001257788.1_29629001_3 - 0.042 14.2 0.1 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Choline_kinase PF01633.18 001257788.1_29629001_3 - 0.095 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Roc PF08477.11 001257788.1_29629001_3 - 0.098 12.8 0.1 18 5.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase APH PF01636.21 001257788.1_29629001_3 - 0.11 12.2 0.0 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABC_tran PF00005.25 001257788.1_29629001_3 - 0.14 12.6 0.1 0.38 11.1 0.1 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.4 001257788.1_29629001_3 - 0.15 12.2 0.3 1.4 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.4 001257788.1_29629001_3 - 0.17 11.5 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NUP50 PF08911.9 001280258.1_39724001_2 - 2.7e-21 75.8 0.8 1.5e-20 73.4 0.8 2.4 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.16 001280258.1_39724001_2 - 2e-11 44.0 0.0 3.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain zf-DHHC PF01529.18 001261328.1_29627001_2 - 9.4e-35 119.5 10.2 1.4e-34 118.9 9.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Piwi PF02171.15 001195514.1_29626001_2 - 1.9e-93 312.9 0.1 2.8e-93 312.3 0.1 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.20 001195514.1_29626001_2 - 7.9e-31 106.6 0.2 1.7e-30 105.5 0.2 1.5 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.3 001195514.1_29626001_2 - 9.6e-07 29.4 0.0 2.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.8 001195514.1_29626001_2 - 0.0044 16.5 0.0 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Argonaute linker 1 domain EF-hand_1 PF00036.30 001110819.1_39724001_2 - 3e-41 135.8 9.7 2.2e-09 36.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001110819.1_39724001_2 - 2.1e-35 120.9 2.9 4.5e-18 65.3 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001110819.1_39724001_2 - 6.2e-33 112.2 9.5 3.4e-15 55.4 0.4 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001110819.1_39724001_2 - 8.7e-29 96.9 5.6 4.4e-09 35.4 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001110819.1_39724001_2 - 6.6e-26 88.5 7.0 1.1e-06 27.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.4 001110819.1_39724001_2 - 1.1e-13 51.2 0.2 4.4e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001110819.1_39724001_2 - 7.8e-09 35.3 0.3 0.00043 20.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001110819.1_39724001_2 - 1.4e-06 28.5 0.0 0.034 14.3 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001110819.1_39724001_2 - 4.4e-05 24.2 0.0 0.0081 16.9 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.8 001110819.1_39724001_2 - 0.00025 20.9 0.8 0.00073 19.4 0.1 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.11 001110819.1_39724001_2 - 0.00035 20.4 0.5 0.28 11.1 0.0 3.6 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0154) DUF4497 PF14924.4 001110819.1_39724001_2 - 0.013 15.8 0.0 6.5 7.1 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF4497) DUF1103 PF06513.9 001110819.1_39724001_2 - 0.024 14.1 2.6 0.041 13.4 2.6 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) DUF2267 PF10025.7 001110819.1_39724001_2 - 0.034 14.3 0.0 0.091 12.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF3349 PF11829.6 001110819.1_39724001_2 - 0.04 14.5 0.3 5.4 7.7 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.14 001110819.1_39724001_2 - 0.041 14.1 0.4 8.5 6.6 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb4 TerB PF05099.11 001110819.1_39724001_2 - 0.07 13.0 0.4 3.5 7.5 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB Caleosin PF05042.11 001110819.1_39724001_2 - 0.084 12.7 0.2 3.3 7.5 0.0 2.8 1 1 2 3 3 3 0 Caleosin related protein SNF PF00209.16 001266900.1_29627001_3 - 1.9e-242 805.5 39.0 2.2e-242 805.3 39.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CD36 PF01130.19 001044622.1_49825001_1 - 3.5e-146 487.3 1.9 4.2e-146 487.0 1.9 1.0 1 0 0 1 1 1 1 CD36 family SLD5_C PF16922.3 001261222.2_29622001_1 - 1.4e-18 66.7 0.1 2.6e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.9 001261222.2_29622001_1 - 1.7e-07 31.6 1.7 3.4e-07 30.6 1.7 1.5 1 0 0 1 1 1 1 GINS complex protein Vta1 PF04652.14 001261520.1_29625001_1 - 3.9e-50 169.5 1.6 1.1e-49 168.0 1.2 1.8 2 0 0 2 2 2 1 Vta1 like NAP PF00956.16 001244317.1_49824001_2 - 7.8e-111 369.4 6.1 1.3e-110 368.6 6.1 1.4 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) zf-H2C2_2 PF13465.4 001194573.1_29624001_1 - 1.6e-16 59.8 26.6 5.7e-10 39.1 0.6 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.24 001194573.1_29624001_1 - 6.6e-11 41.9 44.7 0.00023 21.3 2.4 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001194573.1_29624001_1 - 1.3e-06 28.6 48.1 0.00046 20.7 1.4 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001194573.1_29624001_1 - 0.0056 16.5 2.2 0.0056 16.5 2.2 4.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001194573.1_29624001_1 - 0.01 16.0 21.9 0.23 11.7 0.3 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001194573.1_29624001_1 - 1.6 9.1 25.6 0.049 13.9 2.4 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.4 001194573.1_29624001_1 - 2.9 7.6 25.0 0.39 10.4 0.2 4.2 4 1 0 4 4 4 0 C2H2-type zinc-finger domain ANF_receptor PF01094.26 001265680.1_29627001_2 - 9.9e-94 314.2 0.0 1.2e-93 313.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.20 001265680.1_29627001_2 - 2e-66 224.0 14.6 3.7e-66 223.1 14.6 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.12 001265680.1_29627001_2 - 7.4e-13 48.1 10.2 2.2e-12 46.6 10.2 1.9 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR PIG-P PF08510.10 001265680.1_29627001_3 - 0.063 13.1 3.9 0.15 11.8 3.9 1.6 1 0 0 1 1 1 0 PIG-P Ifi-6-16 PF06140.11 001048169.2_29622001_1 - 9.4e-28 95.8 22.8 9.4e-28 95.8 22.8 2.1 2 0 0 2 2 2 1 Interferon-induced 6-16 family TIR PF01582.18 001279584.1_24225001_1 - 1.3e-27 96.6 0.3 3.2e-27 95.3 0.3 1.7 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001279584.1_24225001_1 - 4.7e-21 74.2 34.6 1.2e-10 40.9 2.8 7.8 3 2 5 9 9 9 7 Leucine rich repeat LRR_4 PF12799.5 001279584.1_24225001_1 - 4.5e-20 71.2 40.8 2e-05 24.7 0.2 9.2 6 2 3 9 9 9 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001279584.1_24225001_1 - 3.6e-12 46.4 0.0 9.4e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001279584.1_24225001_1 - 6e-07 29.0 6.3 0.043 13.2 0.2 3.5 3 0 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.4 001279584.1_24225001_1 - 7.6e-06 25.4 23.4 2.5 8.2 0.0 10.2 10 0 0 10 10 10 2 Leucine Rich repeat LRRCT PF01463.22 001279584.1_24225001_1 - 8.2e-05 22.7 0.0 0.00032 20.9 0.0 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001279584.1_24225001_1 - 0.065 13.6 34.3 7.6 7.3 0.1 10.8 10 2 0 10 10 10 0 Leucine Rich Repeat LysM PF01476.18 001168945.1_40422001_1 - 1.3e-08 34.7 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 LysM domain Rootletin PF15035.4 001169093.1_40429001_1 - 1.1e-59 201.5 18.1 1.1e-59 201.5 18.1 17.5 2 1 12 15 15 15 1 Ciliary rootlet component, centrosome cohesion WD40 PF00400.30 001195650.1_29623001_1 - 2.9e-51 170.2 6.7 8.7e-07 29.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001195650.1_29623001_1 - 2.6e-15 56.3 0.1 0.0022 18.1 0.0 5.7 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001195650.1_29623001_1 - 3e-08 33.7 0.3 0.017 14.8 0.1 3.1 2 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001195650.1_29623001_1 - 3.1e-06 26.3 0.1 3.1 6.5 0.0 4.6 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.14 001195650.1_29623001_1 - 0.00048 18.6 0.1 0.34 9.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.3 001195650.1_29623001_1 - 0.0047 16.1 0.0 1.3 8.1 0.1 2.6 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.6 001195650.1_29623001_1 - 0.0061 15.1 6.6 3.6 5.9 0.0 4.2 2 1 3 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.10 001195650.1_29623001_1 - 0.11 12.3 0.0 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Dysbindin PF04440.14 001261592.1_29624001_3 - 3.1e-41 140.8 0.0 4.3e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) Serpin PF00079.18 001173401.1_09923001_1 - 6e-117 390.9 1.4 6.9e-117 390.7 1.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF3603 PF12227.6 001173401.1_09923001_1 - 0.13 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) RTP1_C1 PF10363.7 001193970.1_29627001_1 - 0.00032 20.7 0.0 0.0014 18.6 0.0 2.2 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.4 001193970.1_29627001_1 - 0.0039 16.6 2.7 1.8 7.9 0.0 3.4 3 1 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II ParcG PF10274.7 001193970.1_29627001_1 - 0.076 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 Parkin co-regulated protein BK_channel_a PF03493.16 001303455.1_39527001_1 - 6e-33 112.9 0.2 1.4e-32 111.7 0.2 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.29 001303455.1_39527001_1 - 2.9e-17 62.6 18.9 7.1e-17 61.3 18.9 1.6 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.14 001303455.1_39527001_1 - 6.5e-14 51.5 4.1 6.5e-14 51.5 4.1 2.6 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.16 001303455.1_39527001_1 - 1.6e-05 25.0 0.1 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Lig_chan PF00060.24 001303455.1_39527001_1 - 0.46 10.2 5.5 0.53 10.0 1.1 2.6 2 1 0 2 2 2 0 Ligand-gated ion channel Troponin PF00992.18 001169067.1_40422001_1 - 2.5e-33 115.1 35.1 2.5e-33 115.1 35.1 3.1 2 1 1 3 3 3 2 Troponin DUF4250 PF14056.4 001169067.1_40422001_1 - 0.1 12.4 0.3 0.32 10.9 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) PAC3 PF10178.7 001193761.1_29622001_2 - 1.3e-26 92.3 0.1 2e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 zf-A20 PF01754.14 001194435.1_29624001_1 - 2.2e-12 46.5 8.8 8.5e-12 44.7 8.8 2.2 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.14 001194435.1_29624001_1 - 6.4e-09 35.7 7.7 6.4e-09 35.7 7.7 4.0 3 0 0 3 3 3 1 AN1-like Zinc finger Troponin PF00992.18 213912.3_49822001_1 - 2.5e-46 157.2 6.2 3.5e-46 156.7 6.2 1.2 1 0 0 1 1 1 1 Troponin DEAD PF00270.27 001168939.1_40424001_1 - 3.9e-44 150.4 0.0 1.1e-42 145.6 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001168939.1_40424001_1 - 5.1e-32 110.4 0.0 8e-30 103.3 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KH_1 PF00013.27 001168939.1_40424001_1 - 2.4e-12 46.3 2.9 2.7e-12 46.2 0.6 2.1 2 0 0 2 2 2 1 KH domain MOEP19 PF16005.3 001168939.1_40424001_1 - 4.9e-05 23.1 0.1 0.00029 20.7 0.0 2.1 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_2 PF07650.15 001168939.1_40424001_1 - 0.00053 19.6 0.2 0.0015 18.2 0.2 1.8 1 0 0 1 1 1 1 KH domain ResIII PF04851.13 001168939.1_40424001_1 - 0.0011 18.9 0.0 0.0062 16.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KH_5 PF13184.4 001168939.1_40424001_1 - 0.0047 16.9 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 NusA-like KH domain Ribosomal_L5 PF00281.17 001168939.1_40424001_1 - 0.068 13.4 0.3 0.2 11.9 0.3 1.8 1 0 0 1 1 1 0 Ribosomal protein L5 Atg8 PF02991.14 001194264.1_29622001_2 - 4.8e-49 164.7 0.1 6.2e-49 164.4 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.11 001194264.1_29622001_2 - 3.7e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 KASH PF10541.7 001194169.1_29624001_2 - 8.3e-13 48.3 6.2 1.6e-12 47.4 6.2 1.4 1 0 0 1 1 1 1 Nuclear envelope localisation domain C2 PF00168.28 001265746.1_29626001_3 - 1.7e-07 31.3 0.0 9.3e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 C2 domain BORG_CEP PF14957.4 001168883.1_40421001_1 - 2.4e-09 38.2 0.0 3.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.26 001168883.1_40421001_1 - 1.8e-06 28.1 0.1 2.9e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain Aminotran_1_2 PF00155.19 001168979.1_40423001_1 - 2e-54 185.0 0.0 2.2e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.18 001168979.1_40423001_1 - 0.00032 19.2 0.0 0.002 16.6 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.15 001168979.1_40423001_1 - 0.036 13.3 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.19 001168979.1_40423001_1 - 0.091 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF863 PF05904.9 001266706.1_29623001_1 - 1.2 7.3 3.7 1.6 6.9 3.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Mito_carr PF00153.25 001266706.1_29623001_3 - 2.2e-61 203.6 0.1 2e-20 72.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sulfotransfer_1 PF00685.25 001265790.1_29624001_1 - 2.9e-19 69.4 0.0 4.3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001265790.1_29624001_1 - 3.1e-10 40.7 1.1 0.00012 22.4 0.0 3.2 3 0 0 3 3 3 2 Sulfotransferase family SSF PF00474.15 001291414.1_49824001_1 - 1.3e-38 132.8 26.5 2.1e-38 132.1 26.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Sushi PF00084.18 001308575.1_39522001_1 - 2.2e-13 50.5 10.2 3.5e-09 37.0 2.3 2.3 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Porin_3 PF01459.20 001261754.1_29624001_1 - 1.7e-82 276.8 4.3 1.9e-82 276.6 4.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pkinase PF00069.23 001258143.2_29626001_3 - 8.5e-50 169.4 0.0 1.2e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001258143.2_29626001_3 - 1.2e-21 77.1 0.0 1.8e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Filament_head PF04732.12 001258143.2_29626001_3 - 0.51 11.1 25.5 0.43 11.4 7.3 2.7 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region bZIP_2 PF07716.13 001139449.1_39522001_1 - 3.2e-16 59.0 11.6 4.9e-16 58.4 11.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.19 001139449.1_39522001_1 - 0.0038 17.2 7.8 0.0064 16.4 7.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.15 001139449.1_39522001_1 - 0.66 10.4 7.8 1 9.8 7.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor LRR_8 PF13855.4 001279679.1_24226001_1 - 2.1e-62 206.6 55.4 1.8e-13 49.9 4.7 10.7 6 2 3 10 10 10 9 Leucine rich repeat TIR PF01582.18 001279679.1_24226001_1 - 5.1e-36 124.0 0.8 8e-36 123.3 0.8 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001279679.1_24226001_1 - 3.4e-27 93.8 61.0 6.9e-05 23.0 3.0 12.0 6 4 7 13 13 13 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001279679.1_24226001_1 - 3.7e-14 52.7 0.3 3.5e-07 30.1 0.1 4.5 3 3 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001279679.1_24226001_1 - 4.2e-11 42.5 18.1 0.004 16.6 0.8 5.8 2 2 4 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.31 001279679.1_24226001_1 - 2.3e-08 33.2 49.7 1.1 9.9 0.7 15.7 16 2 0 16 16 16 4 Leucine Rich Repeat TIR_2 PF13676.4 001279679.1_24226001_1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001279679.1_24226001_1 - 0.0015 18.3 43.2 9.4 6.4 0.0 13.7 15 0 0 15 15 15 2 Leucine Rich repeat LRRCT PF01463.22 001279679.1_24226001_1 - 0.0046 17.3 0.0 0.46 11.0 0.0 3.3 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain PET PF06297.12 001260650.1_29628001_1 - 2.1e-37 127.2 0.8 2.1e-37 127.2 0.8 2.2 2 0 0 2 2 2 1 PET Domain LIM PF00412.20 001260650.1_29628001_1 - 5.4e-24 84.1 51.5 4.8e-10 39.4 14.3 4.2 4 0 0 4 4 4 3 LIM domain RasGEF PF00617.17 001169090.1_40424001_1 - 1.7e-40 138.9 0.0 3e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain EF-hand_1 PF00036.30 001169090.1_40424001_1 - 1.3e-11 43.1 0.8 1.1e-05 24.4 0.2 2.9 2 0 0 2 2 2 2 EF hand C1_1 PF00130.20 001169090.1_40424001_1 - 2e-11 43.4 7.9 3.5e-11 42.7 7.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_6 PF13405.4 001169090.1_40424001_1 - 7.8e-11 40.9 0.2 4.6e-05 22.9 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.4 001169090.1_40424001_1 - 2.9e-10 39.1 0.7 6.3e-06 25.3 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 001169090.1_40424001_1 - 1.7e-09 37.9 0.1 0.0006 20.1 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair RasGEF_N PF00618.18 001169090.1_40424001_1 - 1.8e-06 28.0 0.0 0.00025 21.1 0.0 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif EF-hand_8 PF13833.4 001169090.1_40424001_1 - 3.6e-05 23.3 1.9 0.0027 17.3 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001169090.1_40424001_1 - 0.036 14.3 0.0 6 7.1 0.0 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TGF_beta PF00019.18 001032955.1_29623001_3 - 7.6e-14 52.3 0.2 3.3e-13 50.3 0.2 1.9 1 1 0 1 1 1 1 Transforming growth factor beta like domain Neur_chan_memb PF02932.14 001265649.2_29626001_1 - 5.6e-86 288.3 0.0 7.8e-86 287.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.21 001265649.2_29626001_1 - 9.8e-73 244.0 1.7 1.4e-72 243.5 1.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.7 001265649.2_29626001_1 - 0.33 10.2 10.3 0.042 13.1 4.9 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Claudin_2 PF13903.4 001168871.1_40422001_1 - 4.2e-21 75.5 1.8 6.1e-21 74.9 1.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.18 001168871.1_40422001_1 - 3.5e-20 72.4 1.8 7.2e-20 71.4 1.8 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.9 001168871.1_40422001_1 - 0.007 16.1 0.4 0.011 15.5 0.1 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein Claudin_3 PF06653.9 001168871.1_40422001_1 - 0.0086 15.9 3.5 0.058 13.2 0.6 2.1 2 0 0 2 2 2 1 Tight junction protein, Claudin-like DUF716 PF04819.10 001168871.1_40422001_1 - 0.0087 15.7 0.2 0.018 14.7 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF716) L_HMGIC_fpl PF10242.7 001168871.1_40422001_1 - 0.015 15.4 0.7 0.022 14.8 0.7 1.3 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF4064 PF13273.4 001168871.1_40422001_1 - 0.19 12.0 3.5 1.3 9.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF202 PF02656.13 001168871.1_40422001_1 - 1.2 9.5 7.0 0.16 12.3 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) HD PF01966.20 001279525.1_40424001_1 - 4e-18 65.7 0.0 1.7e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 HD domain SAM_1 PF00536.28 001279525.1_40424001_1 - 2.4e-09 37.4 0.0 5.6e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 001279525.1_40424001_1 - 4e-09 36.3 0.0 9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001279525.1_40424001_1 - 0.0079 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ste50p-SAM PF09235.8 001279525.1_40424001_1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SNAP-25 PF00835.17 001261338.1_29623001_2 - 1.7e-22 79.3 2.9 1.8e-21 76.0 0.9 2.5 2 0 0 2 2 2 1 SNAP-25 family DUF5089 PF17002.3 001261338.1_29623001_2 - 0.0006 19.6 0.3 0.0006 19.6 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.6 001261338.1_29623001_2 - 0.008 16.3 5.3 0.11 12.6 1.5 2.8 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.11 001261338.1_29623001_2 - 0.1 12.4 2.2 0.1 12.4 0.7 1.8 2 0 0 2 2 2 0 Sec20 DUF16 PF01519.14 001261338.1_29623001_2 - 0.85 10.0 5.6 8 6.9 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.10 001261338.1_29623001_2 - 1 9.2 5.4 0.73 9.7 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ion_trans PF00520.29 001173090.1_09927001_1 - 3.4e-10 39.4 21.1 3.4e-10 39.4 21.1 2.0 2 1 0 2 2 2 1 Ion transport protein PEPCK PF00821.16 001265937.2_29625001_3 - 5.9e-276 916.2 0.0 6.8e-276 916.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase wnt PF00110.17 001168687.1_29625001_2 - 1.8e-121 405.3 25.2 2.4e-121 404.8 25.2 1.2 1 0 0 1 1 1 1 wnt family Peptidase_S8 PF00082.20 001257742.1_29626001_3 - 4.8e-49 167.1 5.8 6.3e-49 166.7 5.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.18 001257742.1_29626001_3 - 1.9e-28 98.2 0.0 3.6e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.3 001257742.1_29626001_3 - 1.9e-24 86.2 0.6 3.6e-24 85.3 0.6 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Furin-like_2 PF15913.3 001257742.1_29626001_3 - 0.0047 16.9 1.4 0.0047 16.9 1.4 2.0 1 1 1 2 2 2 1 Furin-like repeat, cysteine-rich DUF357 PF04010.11 001257742.1_29626001_3 - 0.057 13.4 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF357) GF_recep_IV PF14843.4 001257742.1_29626001_3 - 0.075 12.7 19.4 1.5 8.5 19.4 2.5 1 1 0 1 1 1 0 Growth factor receptor domain IV VSP PF03302.11 001257742.1_29626001_3 - 0.11 11.2 17.9 0.16 10.6 6.7 2.3 1 1 0 2 2 2 0 Giardia variant-specific surface protein Sulfotransfer_1 PF00685.25 001265911.1_29625001_2 - 5.4e-58 196.4 0.0 6.8e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001265911.1_29625001_2 - 2.7e-14 54.0 0.0 1.5e-09 38.4 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Interfer-bind PF09294.8 001168783.1_40423001_1 - 1e-44 151.0 1.1 2.9e-24 85.2 0.1 2.8 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.15 001168783.1_40423001_1 - 2e-19 69.2 7.2 6.6e-12 45.1 1.2 3.1 2 1 1 3 3 3 2 Tissue factor fn3 PF00041.19 001168783.1_40423001_1 - 1.2e-06 28.6 0.9 0.016 15.4 0.0 3.7 4 0 0 4 4 4 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.3 001168783.1_40423001_1 - 0.0018 18.6 4.8 0.47 10.9 0.0 3.9 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.7 001168783.1_40423001_1 - 0.024 14.9 0.0 1.7 9.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) RRM_1 PF00076.20 001266389.2_29623001_2 - 1.8e-31 107.7 0.0 1.9e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Es2 PF09751.7 001266389.2_29623001_2 - 0.039 13.6 0.1 0.073 12.7 0.1 1.5 1 0 0 1 1 1 0 Nuclear protein Es2 BRAP2 PF07576.10 001266389.2_29623001_2 - 0.074 13.1 0.0 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 BRCA1-associated protein 2 PHM7_cyt PF14703.4 001266389.2_29623001_2 - 0.15 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Pkinase PF00069.23 001258200.1_29629001_3 - 9.3e-64 215.2 0.0 1.3e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001258200.1_29629001_3 - 1e-46 159.2 0.0 1.4e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001258200.1_29629001_3 - 9.4e-05 21.7 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001258200.1_29629001_3 - 0.045 13.0 0.1 0.07 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_29 PF00777.16 001199734.1_32324001_1 - 3.2e-37 128.3 0.1 6.6e-37 127.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 29 (sialyltransferase) Pkinase_Tyr PF07714.15 001009431.1_39527001_1 - 6.1e-37 127.2 0.0 8.2e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001009431.1_39527001_1 - 7.3e-36 123.8 0.0 1.1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.10 001009431.1_39527001_1 - 2.4e-15 55.6 0.9 5.4e-15 54.5 0.9 1.7 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.21 001009431.1_39527001_1 - 6.8e-13 49.4 11.3 2.2e-12 47.7 11.3 2.0 1 0 0 1 1 1 1 Activin types I and II receptor domain FTA2 PF13095.4 001009431.1_39527001_1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.20 001168888.1_40422001_1 - 8e-20 70.3 0.0 1.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.7 001168888.1_40422001_1 - 0.071 11.8 12.9 0.089 11.5 12.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.7 001168888.1_40422001_1 - 1.1 7.6 6.4 1.1 7.6 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Presenilin PF01080.15 001168888.1_40422001_1 - 2.2 6.8 6.8 2.6 6.6 6.8 1.1 1 0 0 1 1 1 0 Presenilin SOBP PF15279.4 001168888.1_40422001_1 - 2.7 8.3 11.9 4.5 7.6 11.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein M3 PF09213.8 001168888.1_40422001_2 - 0.029 12.9 0.1 0.04 12.5 0.1 1.1 1 0 0 1 1 1 0 M3 IFRD PF05004.11 001266837.1_29624001_2 - 2e-101 339.0 1.6 2.5e-101 338.7 1.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.10 001266837.1_29624001_2 - 1.2e-21 76.9 0.2 3.1e-21 75.6 0.2 1.8 1 0 0 1 1 1 1 Interferon-related protein conserved region Drf_GBD PF06371.11 001266837.1_29624001_2 - 0.023 14.1 0.0 0.08 12.4 0.0 1.7 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain HEAT PF02985.20 001266837.1_29624001_2 - 0.35 11.1 3.7 46 4.5 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Roc PF08477.11 001194507.1_29624001_1 - 7.2e-15 55.2 0.0 2.6e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.20 001194507.1_29624001_1 - 1.4e-12 47.4 0.0 4.3e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.10 001194507.1_29624001_1 - 1.3e-06 27.8 0.0 3.2e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001194507.1_29624001_1 - 7.4e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.19 001194507.1_29624001_1 - 1.2e-05 24.7 0.1 3.5e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001194507.1_29624001_1 - 0.0025 17.6 0.2 0.0081 15.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.4 001194507.1_29624001_1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain IIGP PF05049.11 001194507.1_29624001_1 - 0.02 13.9 0.1 0.033 13.1 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.4 001194507.1_29624001_1 - 0.06 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.25 001194507.1_29624001_1 - 0.088 13.2 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Septin PF00735.16 001194507.1_29624001_1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin DUF87 PF01935.15 001194507.1_29624001_1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_5 PF07728.12 001194507.1_29624001_1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.24 001194507.1_29624001_1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.11 001194507.1_29624001_1 - 0.17 10.9 0.2 0.3 10.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ASC PF00858.22 001173064.1_09924001_1 - 1.3e-97 327.3 18.1 1.5e-97 327.0 18.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel 7tm_1 PF00001.19 001097580.1_22423001_1 - 6.9e-47 159.8 17.8 1.2e-46 159.0 17.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001097580.1_22423001_1 - 4.5e-06 26.1 13.5 6.4e-06 25.6 13.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001097580.1_22423001_1 - 0.094 11.9 11.9 0.0096 15.1 6.7 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srab PF10292.7 001097580.1_22423001_1 - 0.3 9.8 9.3 0.42 9.3 4.6 2.4 2 1 0 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srw PF10324.7 001097580.1_22423001_1 - 0.54 9.4 10.0 0.018 14.2 3.7 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.4 001097580.1_22423001_1 - 5.3 6.6 12.7 0.31 10.6 2.3 2.7 2 1 0 2 2 2 0 Olfactory receptor WD40 PF00400.30 001173058.1_09926001_1 - 2.8e-41 138.6 21.4 5.2e-08 33.3 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001173058.1_09926001_1 - 2.2e-14 53.4 0.0 0.0012 19.0 0.0 5.5 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.3 001173058.1_09926001_1 - 0.00019 20.7 0.0 0.0012 18.1 0.0 2.1 1 1 1 2 2 2 1 WD40-like domain eIF2A PF08662.9 001173058.1_09926001_1 - 0.00065 19.5 0.0 1.1 8.9 0.0 2.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Myc-LZ PF02344.13 001173058.1_09926001_1 - 0.076 13.0 0.5 0.17 11.9 0.5 1.5 1 0 0 1 1 1 0 Myc leucine zipper domain CALM_bind PF16025.3 001173058.1_09926001_1 - 0.27 11.5 0.7 0.55 10.6 0.7 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Ras PF00071.20 001194812.1_29623001_1 - 5.6e-25 87.7 0.1 7e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001194812.1_29623001_1 - 2.1e-10 40.7 0.1 4.1e-10 39.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001194812.1_29623001_1 - 5.6e-07 29.1 0.0 7.4e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001194812.1_29623001_1 - 9.1e-05 22.4 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001194812.1_29623001_1 - 0.00029 20.3 0.1 0.03 13.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.21 001194812.1_29623001_1 - 0.001 19.0 0.2 0.0024 17.8 0.2 1.7 1 1 0 1 1 1 1 Dynamin family DUF2121 PF09894.7 001194812.1_29623001_1 - 0.014 14.8 0.1 0.073 12.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) DUF258 PF03193.14 001194812.1_29623001_1 - 0.018 14.8 0.2 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Nckap1 PF09735.7 001266519.1_29629001_1 - 0 1734.0 28.0 0 1733.8 28.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein TBD PF12845.5 001266519.1_29629001_2 - 1.9 8.3 5.1 0.32 10.8 0.5 2.1 2 0 0 2 2 2 0 TBD domain A_deaminase PF00962.20 001168960.1_40423001_1 - 1.4e-36 126.4 0.1 1.6e-36 126.1 0.1 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.18 001168960.1_40423001_1 - 9.5e-06 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family SEP PF08059.11 001266663.1_29626001_3 - 6.4e-27 93.8 0.1 1.5e-26 92.7 0.1 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.18 001266663.1_29626001_3 - 1e-18 67.1 0.0 2.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.4 001266663.1_29626001_3 - 2.1e-16 59.3 0.4 3.9e-16 58.4 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain Ion_trans PF00520.29 001110418.1_49826001_2 - 2.2e-50 171.1 10.6 3.2e-50 170.5 10.6 1.3 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001110418.1_49826001_2 - 4.1e-28 97.4 0.0 7.3e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001110418.1_49826001_2 - 3e-14 52.6 4.1 3e-14 52.6 4.1 2.6 2 1 1 3 3 3 1 Ion channel PKD_channel PF08016.10 001110418.1_49826001_2 - 0.03 12.9 1.9 0.027 13.0 0.7 1.4 1 1 0 1 1 1 0 Polycystin cation channel 7tm_1 PF00001.19 001194370.1_29626001_1 - 8.7e-31 107.0 19.8 1.4e-30 106.4 19.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SAM_1 PF00536.28 001266465.1_29629001_3 - 5.3e-27 93.9 1.0 4.3e-13 49.4 0.2 4.0 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 001266465.1_29629001_3 - 3.8e-22 78.0 0.5 7.1e-08 32.3 0.1 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) Mpp10 PF04006.10 001266435.1_29625001_3 - 1.5e-215 717.1 80.5 2e-215 716.7 80.5 1.1 1 0 0 1 1 1 1 Mpp10 protein Cadherin PF00028.15 001266613.1_29627001_1 - 7.1e-79 260.2 2.4 7.5e-19 67.8 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.15 001266613.1_29627001_1 - 2e-55 186.5 0.1 3.3e-55 185.9 0.1 1.3 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.3 001266613.1_29627001_1 - 1.7e-06 27.9 2.7 2.9 7.8 0.0 5.4 5 0 0 5 5 5 2 Cadherin-like Cadherin_2 PF08266.10 001266613.1_29627001_1 - 0.0041 16.8 0.0 9.5 6.0 0.0 3.7 3 1 0 3 3 3 2 Cadherin-like ASFV_J13L PF05568.9 001266613.1_29627001_1 - 0.032 13.9 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Gla PF00594.18 001261082.1_29626001_3 - 2.3e-18 65.9 14.3 5e-18 64.9 14.3 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain RCR PF12273.6 001261082.1_29626001_3 - 0.021 15.3 0.0 0.056 14.0 0.0 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF2207 PF09972.7 001261082.1_29626001_3 - 0.047 12.3 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CCSMST1 PF15013.4 001261082.1_29626001_3 - 0.077 13.0 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 CCSMST1 family PROL5-SMR PF15621.4 001261082.1_29626001_3 - 0.23 11.9 2.2 0.43 11.0 2.2 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family TMEM252 PF15664.3 001261082.1_29626001_3 - 2.7 7.6 4.3 2.2 7.9 0.8 2.2 2 0 0 2 2 2 0 Transmembrane protein 252 family IL8 PF00048.18 001132620.1_43528001_1 - 5.7e-06 26.3 1.2 1.7e-05 24.7 1.2 1.8 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like zf-C2H2 PF00096.24 001114673.1_49827001_1 - 4e-27 93.0 64.9 5.4e-06 26.4 0.4 7.8 8 0 0 8 8 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001114673.1_49827001_1 - 2.1e-25 87.8 39.8 2.7e-07 30.6 0.7 7.8 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_4 PF13894.4 001114673.1_49827001_1 - 1.2e-22 78.4 64.4 0.00057 20.4 0.3 8.4 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.5 001114673.1_49827001_1 - 1.4e-14 53.8 42.0 0.014 15.7 0.1 7.6 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001114673.1_49827001_1 - 1.1e-12 47.8 33.0 0.0013 18.9 2.2 7.4 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.10 001114673.1_49827001_1 - 2.9e-06 27.3 20.9 0.0087 16.2 1.4 3.9 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.4 001114673.1_49827001_1 - 0.002 17.9 56.4 0.0052 16.6 2.7 8.4 9 0 0 9 9 9 4 C2H2-type zinc finger NinF PF05810.10 001114673.1_49827001_1 - 0.0035 17.1 0.1 0.018 14.7 0.1 2.2 1 0 0 1 1 1 1 NinF protein DUF3268 PF11672.6 001114673.1_49827001_1 - 0.029 14.6 12.4 0.34 11.1 0.3 3.6 3 0 0 3 3 3 0 zinc-finger-containing domain zf-C2H2_11 PF16622.3 001114673.1_49827001_1 - 0.089 12.4 0.1 0.089 12.4 0.1 7.2 7 0 0 7 7 7 0 zinc-finger C2H2-type Rad50_zn_hook PF04423.12 001114673.1_49827001_1 - 0.58 9.9 3.6 2.1 8.1 0.0 3.3 4 0 0 4 4 3 0 Rad50 zinc hook motif Jas PF16135.3 001114673.1_49827001_1 - 1 9.4 6.1 0.35 10.9 0.8 2.9 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling zf-C2H2_9 PF16293.3 001114673.1_49827001_1 - 1.1 9.0 4.3 7.4 6.4 0.2 3.7 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) DUF2225 PF09986.7 001114673.1_49827001_1 - 1.3 8.5 5.1 0.66 9.5 0.1 2.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Elf1 PF05129.11 001114673.1_49827001_1 - 1.6 8.7 18.9 6.3 6.8 0.2 4.7 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like BolA PF01722.16 001114673.1_49827001_1 - 8.2 6.7 7.9 18 5.6 0.1 3.6 3 1 1 4 4 4 0 BolA-like protein BNIP3 PF06553.10 001037284.1_29623001_1 - 2.9e-84 281.5 3.8 3.8e-84 281.1 3.8 1.1 1 0 0 1 1 1 1 BNIP3 DUF3319 PF11782.6 001037284.1_29623001_1 - 0.038 13.8 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) Steroid_dh PF02544.14 001281626.1_31323001_1 - 5.3e-56 188.6 5.8 7.4e-56 188.2 5.8 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.10 001281626.1_31323001_1 - 0.00028 20.4 0.2 0.00042 19.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) CDI PF02234.17 001261005.1_29623001_2 - 2.7e-21 75.4 2.6 5.1e-21 74.5 2.6 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Multi-haem_cyto PF13447.4 001261005.1_29623001_2 - 0.033 13.3 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH P2X_receptor PF00864.17 001287481.1_09923001_1 - 5.6e-156 519.1 0.0 6.8e-156 518.8 0.0 1.0 1 0 0 1 1 1 1 ATP P2X receptor Nup35_RRM PF05172.11 001266251.1_29623001_2 - 2.4e-26 91.5 0.0 3.9e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.4 001266251.1_29623001_2 - 3.3e-09 36.4 0.0 5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.23 001265624.1_29627001_1 - 6.4e-133 441.9 0.0 4.9e-66 222.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.15 001265624.1_29627001_1 - 9.9e-61 205.1 0.0 1.1e-29 103.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.4 001265624.1_29627001_1 - 1.4e-11 44.2 0.0 7.6e-05 22.0 0.0 2.8 2 1 1 3 3 3 2 Kinase-like APH PF01636.21 001265624.1_29627001_1 - 7.1e-10 39.1 8.3 0.00033 20.5 0.0 4.3 2 2 2 4 4 4 4 Phosphotransferase enzyme family Kdo PF06293.12 001265624.1_29627001_1 - 7.7e-08 31.8 0.1 0.00031 20.0 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001265624.1_29627001_1 - 4.1e-06 26.4 0.1 0.00037 20.0 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase_C PF00433.22 001265624.1_29627001_1 - 5.6e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.4 001265624.1_29627001_1 - 0.00039 20.0 0.1 1.4 8.4 0.0 3.1 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.18 001265624.1_29627001_1 - 0.026 14.0 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Calcyon PF06387.9 001266433.1_29622001_1 - 3.6e-78 261.6 0.0 4.4e-78 261.3 0.0 1.1 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) Troponin PF00992.18 001265640.1_29622001_2 - 9.3e-47 158.6 7.0 1.2e-46 158.2 7.0 1.2 1 0 0 1 1 1 1 Troponin Ank_2 PF12796.5 001306117.1_39525001_1 - 3.7e-26 91.4 6.6 2.2e-12 47.3 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.28 001306117.1_39525001_1 - 1.1e-20 72.9 7.7 0.0045 17.2 0.0 7.1 5 2 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.4 001306117.1_39525001_1 - 7.1e-20 71.0 3.6 0.00031 21.1 0.2 5.8 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.4 001306117.1_39525001_1 - 7e-19 65.8 3.7 0.046 14.1 0.1 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.4 001306117.1_39525001_1 - 5.8e-12 45.5 8.1 0.0014 18.8 0.1 6.1 5 2 2 7 7 7 5 Ankyrin repeats (many copies) IL8 PF00048.18 001032934.1_29621001_1 - 6.4e-08 32.5 1.4 9.6e-08 31.9 1.4 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Gal-bind_lectin PF00337.20 001141937.2_40422001_1 - 2.3e-28 98.2 0.0 2.9e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin DUF1344 PF07076.9 001141937.2_40422001_1 - 0.025 14.3 0.0 0.086 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Serpin PF00079.18 001168913.1_40423001_1 - 1.6e-127 425.7 3.6 1.8e-127 425.6 3.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF45 PF01863.15 001168913.1_40423001_1 - 0.024 14.6 0.3 0.041 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Lip_prot_lig_C PF10437.7 001168913.1_40423001_1 - 0.046 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus TIR PF01582.18 001279638.1_24225001_1 - 2.7e-27 95.6 1.0 4.6e-27 94.8 1.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001279638.1_24225001_1 - 3.1e-21 74.7 28.8 7e-11 41.6 4.9 7.3 3 2 6 9 9 9 6 Leucine rich repeat LRR_4 PF12799.5 001279638.1_24225001_1 - 5.6e-18 64.6 36.0 6.6e-06 26.2 0.2 8.3 6 2 3 9 9 9 6 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001279638.1_24225001_1 - 7.1e-13 48.6 0.0 1.6e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001279638.1_24225001_1 - 1.4e-07 30.8 20.3 0.44 10.6 0.1 10.3 11 0 0 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.4 001279638.1_24225001_1 - 8.9e-07 28.4 9.3 0.0038 16.6 0.6 4.0 3 1 1 4 4 4 2 Leucine-rich repeat LRRCT PF01463.22 001279638.1_24225001_1 - 8e-05 22.8 0.0 0.00032 20.9 0.0 2.2 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001279638.1_24225001_1 - 0.00067 19.6 33.5 0.79 10.3 0.3 11.1 9 3 1 10 10 10 2 Leucine Rich Repeat TIR-like PF10137.7 001279638.1_24225001_1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain SSDP PF04503.11 001260682.1_29624001_3 - 7.6e-79 265.8 69.4 7.1e-64 216.7 58.2 2.2 1 1 1 2 2 2 2 Single-stranded DNA binding protein, SSDP Avl9 PF09794.7 001261098.1_29625001_3 - 2.9e-157 523.1 0.0 3.6e-157 522.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.7 001261098.1_29625001_3 - 9.4e-11 41.7 0.7 4.4e-07 29.6 0.7 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.8 001261098.1_29625001_3 - 5.4e-08 32.7 0.0 0.00032 20.5 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.10 001261098.1_29625001_3 - 1.2e-07 32.1 0.5 3e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.19 001261098.1_29625001_3 - 0.0012 18.7 1.7 1 9.2 0.4 2.3 2 0 0 2 2 2 2 DENN (AEX-3) domain Condensin2nSMC PF12422.6 001261098.1_29625001_3 - 0.16 12.0 0.4 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit VWC PF00093.16 001257873.1_29624001_3 - 6.3e-24 83.9 65.6 3.2e-09 36.8 16.1 4.4 5 0 0 5 5 5 3 von Willebrand factor type C domain DUF1496 PF07383.10 001257873.1_29624001_3 - 0.033 13.6 2.5 2.8 7.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1496) Amnionless PF14828.4 001257873.1_29624001_3 - 0.24 10.1 55.8 0.028 13.2 10.3 3.2 2 1 1 3 3 3 0 Amnionless UQ_con PF00179.24 001077219.1_49822001_1 - 4.6e-18 65.1 0.0 8.1e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001077219.1_49822001_1 - 0.06 13.5 0.1 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 RWD domain Transket_pyr PF02779.22 001168799.1_40424001_1 - 2.5e-38 131.4 0.6 3.7e-38 130.8 0.1 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 001168799.1_40424001_1 - 3.7e-31 107.4 1.5 6.2e-31 106.7 0.3 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transketolase_N PF00456.19 001168799.1_40424001_1 - 6.8e-30 104.0 0.0 3.4e-22 78.7 0.0 2.4 1 1 1 2 2 2 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.18 001168799.1_40424001_1 - 5.5e-07 28.7 0.0 8.7e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.4 001168799.1_40424001_1 - 0.022 13.8 0.0 0.56 9.2 0.0 2.8 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase zf-BED PF02892.13 001194409.1_29626001_1 - 0.19 11.7 5.2 0.19 11.7 1.4 2.4 2 0 0 2 2 2 0 BED zinc finger Lebercilin PF15619.4 001194409.1_29626001_3 - 4.6e-66 222.0 44.2 4.6e-66 222.0 44.2 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF1515 PF07439.9 001194409.1_29626001_3 - 2.1 8.3 7.6 4.5 7.2 3.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) adh_short PF00106.23 001285824.1_29523001_1 - 3.7e-47 160.2 0.0 4.6e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001285824.1_29523001_1 - 4.1e-25 88.6 0.0 5.9e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001285824.1_29523001_1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Ins_allergen_rp PF06757.11 001285824.1_29523001_1 - 0.0056 16.6 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 Insect allergen related repeat, nitrile-specifier detoxification Epimerase PF01370.19 001285824.1_29523001_1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glucos_trans_II PF14264.4 001285824.1_29523001_1 - 0.019 14.2 3.4 0.23 10.6 2.8 2.1 2 0 0 2 2 2 0 Glucosyl transferase GtrII DUF4131 PF13567.4 001285824.1_29523001_1 - 9.1 5.7 7.4 3 7.3 4.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) E1-E2_ATPase PF00122.18 001266472.1_29628001_1 - 2.6e-58 196.8 2.9 5.1e-58 195.9 2.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.19 001266472.1_29628001_1 - 2e-44 151.4 1.9 2.7e-44 150.9 0.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.4 001266472.1_29628001_1 - 1.4e-24 85.8 0.0 3.3e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.24 001266472.1_29628001_1 - 6e-19 69.0 0.1 1.1e-15 58.3 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 001266472.1_29628001_1 - 1.3e-18 66.3 0.0 2.6e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.10 001266472.1_29628001_1 - 8e-06 25.6 0.9 0.00088 18.9 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FMN_dh PF01070.16 001243431.1_49824001_2 - 2.4e-134 447.6 0.1 2.8e-134 447.4 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.23 001243431.1_49824001_2 - 3.1e-07 29.6 0.5 1.2e-06 27.6 0.3 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.15 001243431.1_49824001_2 - 0.00026 20.1 0.1 0.00038 19.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.12 001243431.1_49824001_2 - 0.0027 16.9 0.2 0.34 10.0 0.1 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.19 001243431.1_49824001_2 - 0.004 16.5 0.1 0.013 14.9 0.1 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.15 001243431.1_49824001_2 - 0.0053 16.0 0.1 0.019 14.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Dus PF01207.15 001243431.1_49824001_2 - 0.012 14.6 0.0 3.9 6.3 0.0 2.3 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) NMO PF03060.13 001243431.1_49824001_2 - 0.013 14.8 0.3 0.019 14.2 0.3 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase G3P_antiterm PF04309.10 001243431.1_49824001_2 - 0.083 12.2 0.0 8.4 5.6 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Filamin PF00630.17 001168801.1_40429001_1 - 0 1297.0 55.7 6e-20 71.9 0.5 24.2 24 0 0 24 24 24 24 Filamin/ABP280 repeat CH PF00307.29 001168801.1_40429001_1 - 1.7e-39 134.3 0.6 4.8e-21 74.9 0.8 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.11 001168801.1_40429001_1 - 2.7e-15 55.9 16.8 0.36 10.7 0.0 12.4 14 0 0 14 14 14 4 Y_Y_Y domain DUF5060 PF16586.3 001168801.1_40429001_1 - 1.6e-14 53.8 0.5 3.7 7.8 0.0 14.0 18 0 0 18 18 17 1 Domain of unknown function (DUF5060) Big_3_5 PF16640.3 001168801.1_40429001_1 - 1.1e-12 47.8 50.0 0.55 10.3 0.0 16.4 18 0 0 18 18 18 5 Bacterial Ig-like domain (group 3) YtkA PF13115.4 001168801.1_40429001_1 - 3.9e-09 36.9 12.4 0.35 11.4 0.2 11.5 15 0 0 15 15 12 2 YtkA-like PapC_N PF13954.4 001168801.1_40429001_1 - 0.00017 21.4 0.0 2.1 8.2 0.0 6.5 5 1 1 6 6 6 1 PapC N-terminal domain Invasin_D3 PF09134.8 001168801.1_40429001_1 - 0.00025 20.6 8.2 6.2 6.5 0.0 8.4 9 0 0 9 9 9 1 Invasin, domain 3 EMP24_GP25L PF01105.22 001168801.1_40429001_1 - 0.00078 19.3 5.5 6 6.6 0.1 7.8 10 0 0 10 10 10 1 emp24/gp25L/p24 family/GOLD CAMSAP_CH PF11971.6 001168801.1_40429001_1 - 0.028 14.1 0.1 2.1 8.1 0.1 2.6 2 0 0 2 2 2 0 CAMSAP CH domain CBM60 PF16841.3 001168801.1_40429001_1 - 0.065 13.5 4.2 14 6.0 0.0 5.7 5 0 0 5 5 5 0 Ca-dependent carbohydrate-binding module xylan-binding FixH PF05751.9 001168801.1_40429001_1 - 0.081 12.8 0.0 7.5 6.4 0.0 4.2 5 0 0 5 5 4 0 FixH CH_2 PF06294.9 001168801.1_40429001_1 - 0.15 12.1 0.4 3.2 7.8 0.2 2.2 2 0 0 2 2 2 0 CH-like domain in sperm protein Rib PF08428.8 001168801.1_40429001_1 - 2 8.3 14.2 4.1 7.3 1.8 5.8 5 0 0 5 5 5 0 Rib/alpha-like repeat Ion_trans PF00520.29 001267017.1_29629001_1 - 4.8e-36 124.1 10.7 6.7e-36 123.6 10.7 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.5 001267017.1_29629001_1 - 3.7e-16 59.1 0.1 7.3e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.27 001267017.1_29629001_1 - 8.4e-14 51.2 0.0 1.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.14 001267017.1_29629001_1 - 5.3e-12 45.4 2.0 1.3e-11 44.2 2.0 1.6 1 0 0 1 1 1 1 Ion channel PAS PF00989.23 001267017.1_29629001_1 - 4.5e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.10 001267017.1_29629001_1 - 0.00013 22.1 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.8 001267017.1_29629001_1 - 0.04 14.0 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold Cupin_2 PF07883.9 001267017.1_29629001_1 - 0.11 12.2 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_3 PF05899.10 001267017.1_29629001_1 - 0.13 11.8 0.8 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Motile_Sperm PF00635.24 001287680.1_29525001_2 - 9.4e-32 109.0 0.1 1.5e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ZapB PF06005.10 001287680.1_29525001_2 - 0.029 14.7 1.3 0.051 13.9 1.3 1.2 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.19 001287680.1_29525001_2 - 0.21 11.6 1.7 0.36 10.8 1.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor 7tm_1 PF00001.19 001040287.1_39523001_1 - 6.9e-42 143.4 0.0 3.1e-41 141.3 0.0 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DNA_pol_A_exo1 PF01612.18 001134677.1_43529001_1 - 3.4e-35 121.2 0.1 1.6e-34 119.0 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease RQC PF09382.8 001134677.1_43529001_1 - 2e-17 62.9 0.0 4.5e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.29 001134677.1_43529001_1 - 1.5e-16 60.6 0.0 8.6e-16 58.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.27 001134677.1_43529001_1 - 3e-15 56.3 0.0 3.2e-13 49.7 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase HTH_40 PF14493.4 001134677.1_43529001_1 - 4.3e-14 52.6 0.0 1.4e-13 51.0 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HRDC PF00570.21 001134677.1_43529001_1 - 1.2e-11 44.3 0.0 3.4e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.3 001134677.1_43529001_1 - 1.1e-09 38.7 1.9 3.9e-09 36.9 1.9 2.1 1 0 0 1 1 1 1 RecQ zinc-binding Laminin_II PF06009.10 001134677.1_43529001_1 - 0.021 14.7 0.8 0.055 13.3 0.8 1.7 1 0 0 1 1 1 0 Laminin Domain II ResIII PF04851.13 001134677.1_43529001_1 - 0.092 12.6 3.1 0.26 11.1 0.0 3.3 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Ion_trans PF00520.29 001258108.1_29627001_1 - 9.7e-52 175.5 5.4 1.3e-51 175.1 5.4 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001258108.1_29627001_1 - 1.4e-27 95.7 0.0 2.3e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001258108.1_29627001_1 - 5.8e-13 48.5 6.3 5.8e-13 48.5 6.3 2.1 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.10 001258108.1_29627001_1 - 0.011 14.3 0.9 0.018 13.6 0.9 1.2 1 0 0 1 1 1 0 Polycystin cation channel MAT1 PF06391.11 001261796.1_29623001_3 - 1.6e-62 210.8 21.7 1.9e-62 210.6 21.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.3 001261796.1_29623001_3 - 5.5e-13 48.4 4.7 1.1e-12 47.5 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001261796.1_29623001_3 - 0.00022 21.0 6.1 0.00063 19.5 6.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.23 001261796.1_29623001_3 - 0.00024 20.8 4.1 0.00079 19.1 4.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001261796.1_29623001_3 - 0.00095 19.0 6.7 0.0023 17.8 6.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 001261796.1_29623001_3 - 0.0011 18.6 5.1 0.0011 18.6 5.1 2.3 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001261796.1_29623001_3 - 0.014 15.1 7.5 0.051 13.3 7.2 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001261796.1_29623001_3 - 0.024 14.7 4.6 0.024 14.7 4.6 1.8 2 0 0 2 2 1 0 Ring finger domain DNA_ligase_ZBD PF03119.14 001261796.1_29623001_3 - 0.04 13.8 0.5 0.35 10.8 0.0 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.5 001261796.1_29623001_3 - 0.063 13.2 7.5 0.81 9.6 8.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-UDP PF14569.4 001261796.1_29623001_3 - 0.08 12.9 0.6 0.08 12.9 0.6 2.7 2 1 1 3 3 3 0 Zinc-binding RING-finger zf-RING_4 PF14570.4 001261796.1_29623001_3 - 0.14 11.8 6.4 0.11 12.1 0.4 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LMBR1 PF04791.14 001261796.1_29623001_3 - 0.15 10.8 3.5 0.18 10.5 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C3HC4_4 PF15227.4 001261796.1_29623001_3 - 0.28 11.3 5.2 1 9.5 5.2 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Poty_PP PF08440.8 001261796.1_29623001_3 - 0.93 8.4 6.5 1.3 7.9 6.5 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein Prok-RING_4 PF14447.4 001261796.1_29623001_3 - 1.2 8.9 13.4 0.43 10.4 7.3 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Auto_anti-p27 PF06677.10 001261796.1_29623001_3 - 1.6 8.8 7.2 1.9 8.6 0.1 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Mu-like_Com PF10122.7 001261796.1_29623001_3 - 2.8 7.3 0.0 2.8 7.3 0.0 3.4 3 0 0 3 3 3 0 Mu-like prophage protein Com DNA_ligase_A_M PF01068.19 001265970.1_29628001_2 - 4.5e-62 209.2 0.0 7.4e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.12 001265970.1_29628001_2 - 9e-34 117.2 1.0 1.4e-33 116.5 0.1 1.8 2 0 0 2 2 2 1 DNA ligase N terminus LIG3_BRCT PF16759.3 001265970.1_29628001_2 - 6.8e-27 93.5 0.0 1.7e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain zf-PARP PF00645.16 001265970.1_29628001_2 - 2.6e-23 82.5 2.3 7.7e-23 81.0 2.3 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DNA_ligase_A_C PF04679.13 001265970.1_29628001_2 - 6.4e-19 68.2 0.0 1.5e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.3 001265970.1_29628001_2 - 1.1e-06 28.8 0.0 3.6e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.8 001265970.1_29628001_2 - 5.6e-05 23.3 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.17 001265970.1_29628001_2 - 0.05 13.3 0.2 0.13 11.9 0.2 1.7 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain Synaptonemal_3 PF15191.4 001265970.1_29628001_2 - 0.13 11.9 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 HD_2 PF12917.5 001265970.1_29628001_2 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme KH_1 PF00013.27 001257743.1_29627001_3 - 1.1e-67 223.6 16.7 1.4e-18 66.3 0.6 4.2 4 0 0 4 4 4 4 KH domain KH_2 PF07650.15 001257743.1_29627001_3 - 3.4e-20 71.5 8.4 5.2e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_4 PF13083.4 001257743.1_29627001_3 - 1.2e-10 40.9 9.6 0.042 13.6 0.1 4.4 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.8 001257743.1_29627001_3 - 0.00023 20.5 15.6 0.0029 16.9 3.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1897) KH_5 PF13184.4 001257743.1_29627001_3 - 0.028 14.3 10.8 4.8 7.2 0.2 4.4 4 0 0 4 4 4 0 NusA-like KH domain IFRD PF05004.11 001284759.1_29525001_2 - 9.6e-112 372.9 3.3 1.2e-111 372.6 3.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.10 001284759.1_29525001_2 - 1.4e-24 86.3 0.6 4.6e-24 84.6 0.6 2.0 1 0 0 1 1 1 1 Interferon-related protein conserved region DEAD PF00270.27 001244543.1_49824001_3 - 4.7e-39 133.8 0.1 8.5e-39 133.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001244543.1_49824001_3 - 7.3e-29 100.3 0.0 1.7e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001244543.1_49824001_3 - 1.4e-08 34.8 0.0 2.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.4 001244543.1_49824001_3 - 0.00091 19.4 0.1 0.0035 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.12 001244543.1_49824001_3 - 0.087 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Helicase SSB PF00436.23 001266152.1_29622001_2 - 4.9e-32 109.9 0.1 6.5e-32 109.5 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family LRR_6 PF13516.4 001266740.1_29629001_1 - 5.4e-24 82.0 3.4 0.02 14.8 0.2 11.0 11 0 0 11 11 11 7 Leucine Rich repeat F-box-like PF12937.5 001266740.1_29629001_1 - 2.8e-16 59.0 4.2 8e-16 57.5 4.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.5 001266740.1_29629001_1 - 4.8e-13 48.9 0.0 0.075 13.3 0.0 6.8 4 2 2 7 7 7 4 Leucine Rich repeats (2 copies) F-box PF00646.31 001266740.1_29629001_1 - 6.7e-12 44.8 2.4 2.5e-11 43.0 2.4 2.1 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.31 001266740.1_29629001_1 - 1.7e-07 30.6 7.7 8.2 7.2 0.0 9.9 10 0 0 10 10 10 2 Leucine Rich Repeat DUF3399 PF11879.6 001278468.1_29626001_1 - 7.2e-45 151.5 8.6 1.5e-44 150.4 8.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3399) Ion_trans PF00520.29 001278468.1_29626001_1 - 5.2e-43 146.9 14.3 7.4e-43 146.4 14.3 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001278468.1_29626001_1 - 9.7e-29 99.4 0.1 2.6e-28 98.1 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Shal-type PF11601.6 001278468.1_29626001_1 - 2e-14 52.7 12.0 4.3e-14 51.6 12.0 1.6 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal Ion_trans_2 PF07885.14 001278468.1_29626001_1 - 5.6e-13 48.5 5.9 5.6e-13 48.5 5.9 2.4 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.3 001278468.1_29626001_1 - 6.5e-05 22.9 0.0 0.00032 20.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain PKD_channel PF08016.10 001278468.1_29626001_1 - 0.0078 14.8 9.2 0.0089 14.6 8.5 1.3 1 1 0 1 1 1 1 Polycystin cation channel SPAR_C PF11881.6 001266525.1_29629001_3 - 7.1e-84 281.3 15.2 7.1e-84 281.3 15.2 2.7 2 0 0 2 2 1 1 C-terminal domain of SPAR protein Rap_GAP PF02145.13 001266525.1_29629001_3 - 3.5e-68 228.7 0.1 7e-68 227.7 0.1 1.5 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.22 001266525.1_29629001_3 - 9.2e-05 22.6 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Rootletin PF15035.4 001266525.1_29629001_3 - 0.01 15.8 4.6 0.024 14.6 4.6 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4164 PF13747.4 001266525.1_29629001_3 - 0.011 15.8 2.3 0.032 14.4 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ATG16 PF08614.9 001266525.1_29629001_3 - 0.018 15.1 7.5 0.068 13.2 7.5 2.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2046 PF09755.7 001266525.1_29629001_3 - 0.024 13.8 4.0 0.047 12.8 4.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) TMF_TATA_bd PF12325.6 001266525.1_29629001_3 - 0.038 14.1 2.3 0.13 12.3 2.3 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Sec34 PF04136.13 001266525.1_29629001_3 - 0.044 13.5 1.7 0.11 12.3 1.7 1.6 1 0 0 1 1 1 0 Sec34-like family RasGAP_C PF03836.13 001266525.1_29629001_3 - 0.074 13.1 0.7 0.31 11.1 0.1 2.3 3 0 0 3 3 3 0 RasGAP C-terminus IncA PF04156.12 001266525.1_29629001_3 - 0.099 12.3 7.4 0.23 11.1 7.4 1.5 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.11 001266525.1_29629001_3 - 0.15 12.6 2.6 0.54 10.8 2.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ZapB PF06005.10 001266525.1_29629001_3 - 1 9.7 8.4 2.5 8.5 8.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB ATP-synt_D PF01813.15 001195715.1_29623001_2 - 6.3e-76 254.5 9.1 8e-76 254.1 9.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D IFRD PF05004.11 001261783.1_29625001_1 - 5.8e-112 373.6 3.5 7.1e-112 373.3 3.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.10 001261783.1_29625001_1 - 1.5e-24 86.2 0.6 4.5e-24 84.7 0.6 1.9 1 0 0 1 1 1 1 Interferon-related protein conserved region Serpin PF00079.18 001168916.1_40423001_1 - 5.1e-131 437.2 0.3 5.7e-131 437.1 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Lipocalin_7 PF14651.4 001287558.1_09021001_3 - 1e-28 99.7 6.0 1.2e-28 99.5 6.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Atrophin-1 PF03154.13 001265662.2_29629001_2 - 0 1733.6 154.4 0 1733.6 154.4 2.3 2 0 0 2 2 2 2 Atrophin-1 family ELM2 PF01448.22 001265662.2_29629001_2 - 3.3e-14 53.2 0.1 6.4e-13 49.1 0.0 3.0 2 0 0 2 2 2 1 ELM2 domain BAH PF01426.16 001265662.2_29629001_2 - 3.4e-13 49.3 0.0 7.1e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 BAH domain GATA PF00320.25 001265662.2_29629001_2 - 1.6e-10 40.3 2.6 3.4e-10 39.2 2.6 1.6 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.29 001265662.2_29629001_2 - 0.0035 17.3 0.2 0.0074 16.3 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Apolipoprotein PF01442.16 001168768.1_40423001_1 - 3.4e-58 196.6 17.4 2.8e-56 190.4 7.4 3.4 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.9 001168768.1_40423001_1 - 5e-05 23.3 1.3 0.022 14.7 0.0 3.4 2 1 1 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.13 001168768.1_40423001_1 - 0.00079 19.0 9.6 0.064 12.7 0.5 2.3 1 1 0 2 2 2 2 Exonuclease VII, large subunit YtxH PF12732.5 001168768.1_40423001_1 - 0.012 16.0 1.8 0.38 11.2 0.2 3.8 3 1 0 3 3 2 0 YtxH-like protein TraC_F_IV PF11130.6 001168768.1_40423001_1 - 0.017 14.6 2.5 0.041 13.3 2.0 2.0 1 1 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer BcrAD_BadFG PF01869.18 001168768.1_40423001_1 - 0.019 14.3 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family SICA_alpha PF12887.5 001168768.1_40423001_1 - 0.026 14.3 0.8 16 5.2 0.0 3.9 3 1 1 4 4 4 0 SICA extracellular alpha domain ApoA-II PF04711.11 001168768.1_40423001_1 - 0.1 12.7 1.5 0.34 11.0 0.1 2.5 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) Serine_rich PF08824.8 001168768.1_40423001_1 - 0.1 12.4 5.8 0.11 12.4 0.2 2.6 3 1 0 3 3 2 0 Serine rich protein interaction domain DUF1664 PF07889.10 001168768.1_40423001_1 - 0.2 11.5 5.7 1.1 9.1 0.6 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF883 PF05957.11 001168768.1_40423001_1 - 0.21 12.0 14.9 2.2 8.8 0.5 5.3 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF883) DUF4795 PF16043.3 001168768.1_40423001_1 - 0.25 10.8 9.4 1.5 8.2 4.0 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3538 PF12057.6 001168768.1_40423001_1 - 0.38 10.3 4.2 0.7 9.5 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3538) DUF479 PF04336.10 001168768.1_40423001_1 - 0.56 10.5 6.2 1.5 9.1 0.4 3.7 1 1 2 3 3 3 0 Protein of unknown function, DUF479 Baculo_PEP_C PF04513.10 001168768.1_40423001_1 - 0.68 9.8 10.7 57 3.6 0.3 5.0 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1917 PF08939.8 001168768.1_40423001_1 - 2.9 7.5 5.0 2.8 7.6 0.9 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF1917) Utp12 PF04003.10 001168768.1_40423001_1 - 8.3 6.6 6.8 64 3.8 0.0 3.9 4 1 0 4 4 4 0 Dip2/Utp12 Family Laminin_I PF06008.12 001168768.1_40423001_1 - 8.3 5.9 17.3 1.5 8.3 0.1 4.0 2 1 0 4 4 4 0 Laminin Domain I UQ_con PF00179.24 001285657.1_09022001_1 - 3.6e-46 156.2 0.0 4.5e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.29 001285657.1_09022001_1 - 4.3e-11 42.4 0.0 9.9e-11 41.2 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.4 001285657.1_09022001_1 - 2.9e-06 26.9 0.0 5.6e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001285657.1_09022001_1 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.11 001285657.1_09022001_1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 UEV domain UBA_3 PF09288.8 001285657.1_09022001_1 - 0.082 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UFC1 PF08694.9 001285657.1_09022001_1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Ferritin PF00210.22 001172847.1_09922001_1 - 1.2e-38 132.1 5.0 1.5e-38 131.8 5.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.15 001172847.1_09922001_1 - 0.01 16.1 1.1 0.013 15.8 0.8 1.5 1 1 0 1 1 1 0 Rubrerythrin Coat_F PF07875.10 001172847.1_09922001_1 - 2.8 8.1 6.1 18 5.5 0.4 2.6 2 0 0 2 2 2 0 Coat F domain ECH_1 PF00378.18 001044607.2_49822001_2 - 1.7e-52 178.1 0.2 3.3e-52 177.2 0.2 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.3 001044607.2_49822001_2 - 7.4e-31 107.8 0.1 1.4e-28 100.3 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Pkinase PF00069.23 001169001.1_40429001_1 - 1.5e-54 185.0 0.0 2.6e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.20 001169001.1_40429001_1 - 1.2e-52 179.0 0.0 1.9e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.15 001169001.1_40429001_1 - 2.1e-27 95.9 0.0 3.7e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DMPK_coil PF08826.8 001169001.1_40429001_1 - 2e-19 69.3 19.5 2e-19 69.3 19.5 6.5 5 1 1 6 6 5 1 DMPK coiled coil domain like C1_1 PF00130.20 001169001.1_40429001_1 - 1.7e-09 37.3 0.7 1.7e-09 37.3 0.7 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.4 001169001.1_40429001_1 - 1.1e-06 28.1 0.0 2.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Kinase-like PH PF00169.27 001169001.1_40429001_1 - 8.3e-05 22.9 0.0 0.00031 21.1 0.0 1.9 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.22 001169001.1_40429001_1 - 0.00061 20.3 0.1 0.0018 18.8 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain PBD PF00786.26 001169001.1_40429001_1 - 0.0019 18.4 0.4 0.0061 16.8 0.4 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain FTA2 PF13095.4 001169001.1_40429001_1 - 0.0095 15.5 0.0 6.1 6.3 0.0 2.9 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.9 001169001.1_40429001_1 - 0.13 11.1 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 IncA PF04156.12 001169001.1_40429001_1 - 3.7 7.2 78.6 0.25 11.0 23.8 4.5 3 1 1 4 4 4 0 IncA protein Filament PF00038.19 001169001.1_40429001_1 - 3.8 6.9 61.0 0.43 10.0 11.5 3.6 1 1 1 3 3 3 0 Intermediate filament protein SLT_2 PF13406.4 001194234.1_29622001_1 - 0.0028 16.8 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT PF01464.18 001194234.1_29622001_1 - 0.0056 16.2 0.0 0.0093 15.5 0.0 1.4 1 1 0 1 1 1 1 Transglycosylase SLT domain P2X_receptor PF00864.17 001281791.1_09923001_1 - 1e-172 574.1 0.3 1.2e-172 574.0 0.3 1.0 1 0 0 1 1 1 1 ATP P2X receptor V-set PF07686.15 001009214.1_39522001_1 - 2.4e-08 34.0 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001009214.1_39522001_1 - 0.0062 17.0 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain V-set_2 PF15910.3 001009214.1_39522001_1 - 0.056 13.4 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 ICOS V-set domain I-set PF07679.14 001009214.1_39522001_1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin I-set domain TNFR_c6 PF00020.16 001166185.1_39523001_1 - 3.7e-19 68.7 54.9 1.1e-10 41.6 5.2 4.4 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region Death PF00531.20 001166185.1_39523001_1 - 6.9e-19 67.7 0.3 1.2e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 Death domain GKAP PF03359.11 001266455.1_29629001_3 - 7.1e-132 440.0 8.1 7.1e-132 440.0 8.1 2.3 1 1 0 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein IL8 PF00048.18 001032849.1_29621001_1 - 2.6e-18 65.8 1.7 3.7e-18 65.3 1.7 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like SelP_C PF04593.12 001032849.1_29621001_1 - 0.011 15.5 0.8 0.012 15.5 0.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, C terminal region EHN PF06441.10 001285557.1_09024001_3 - 8.1e-35 119.2 0.2 1.4e-34 118.4 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.18 001285557.1_09024001_3 - 3.7e-25 88.9 0.0 1.5e-24 86.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001285557.1_09024001_3 - 0.0031 18.0 0.0 0.027 15.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Myosin_head PF00063.19 001163066.1_37929001_1 - 1.1e-285 949.1 2.3 1.1e-285 949.1 2.3 3.5 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.17 001163066.1_37929001_1 - 3.6e-155 518.4 275.7 4.3e-155 518.1 275.7 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.17 001163066.1_37929001_1 - 5.7e-12 45.1 0.0 1.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.25 001163066.1_37929001_1 - 0.0066 16.0 0.5 0.095 12.4 0.1 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif Reo_sigmaC PF04582.10 001163066.1_37929001_1 - 0.026 13.8 78.0 0.44 9.8 4.9 9.2 1 1 7 9 9 9 0 Reovirus sigma C capsid protein DUF4537 PF15057.4 001163066.1_37929001_1 - 0.052 13.4 0.1 0.46 10.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) AAA_22 PF13401.4 001163066.1_37929001_1 - 0.11 12.7 0.0 0.11 12.7 0.0 6.0 4 3 2 6 6 6 0 AAA domain YqjK PF13997.4 001163066.1_37929001_1 - 2.1 8.5 6.2 0.76 9.9 0.2 3.6 4 0 0 4 4 4 0 YqjK-like protein Filament PF00038.19 001163066.1_37929001_1 - 2.8 7.3 237.0 0.016 14.7 54.8 7.3 1 1 6 7 7 7 0 Intermediate filament protein Mab-21 PF03281.12 001283399.1_29525001_2 - 1.9e-99 332.6 0.0 2.5e-99 332.2 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein Metallophos PF00149.26 001244404.1_49824001_3 - 7.5e-36 124.4 0.2 9.9e-36 124.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FIBP PF05427.9 001244509.1_49823001_1 - 2e-171 570.0 1.4 2.3e-171 569.8 1.4 1.0 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) EBP50_C PF09007.9 001143724.1_49824001_3 - 4.8e-43 147.1 8.8 4.8e-43 147.1 8.8 2.2 3 0 0 3 3 3 1 EBP50, C-terminal PDZ PF00595.22 001143724.1_49824001_3 - 1.1e-29 102.4 0.2 1.5e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001143724.1_49824001_3 - 1.2e-14 54.3 0.2 5.9e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain GRASP55_65 PF04495.12 001143724.1_49824001_3 - 0.011 15.9 0.0 4.5 7.5 0.0 2.2 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.4 001143724.1_49824001_3 - 0.062 13.2 0.2 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF2360 PF10152.7 001143724.1_49824001_3 - 3.5 7.9 8.0 2.6 8.3 0.9 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) CaM-KIIN PF15170.4 001260527.1_29621001_1 - 4.9e-47 157.9 0.0 6e-47 157.6 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin-dependent protein kinase II inhibitor Tctex-1 PF03645.11 001266527.1_29624001_3 - 4.2e-26 91.0 1.8 6.2e-26 90.5 1.8 1.3 1 0 0 1 1 1 1 Tctex-1 family FUSC PF04632.10 001266747.1_29625001_3 - 4 5.7 5.6 7.4 4.9 5.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family RRM_1 PF00076.20 001260894.1_29623001_1 - 2.4e-25 88.0 0.3 1.1e-13 50.7 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001260894.1_29623001_1 - 3.7e-07 29.6 0.1 0.0097 15.4 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001260894.1_29623001_1 - 1.1e-06 28.3 0.0 0.0077 15.9 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Calcipressin PF04847.10 001260894.1_29623001_1 - 0.045 13.4 0.4 0.62 9.6 0.0 2.5 1 1 1 2 2 2 0 Calcipressin TIR PF01582.18 001285540.1_09025001_1 - 9e-21 74.3 0.4 1.6e-20 73.5 0.4 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001285540.1_09025001_1 - 3.7e-19 68.1 33.4 1.6e-10 40.5 4.6 7.5 2 2 6 8 8 8 6 Leucine rich repeat LRR_4 PF12799.5 001285540.1_09025001_1 - 9e-15 54.4 43.6 2.6e-06 27.5 0.9 7.8 5 3 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.4 001285540.1_09025001_1 - 1.6e-10 40.1 23.4 0.36 10.9 0.1 10.0 10 0 0 10 10 10 4 Leucine Rich repeat TIR_2 PF13676.4 001285540.1_09025001_1 - 1.6e-08 34.7 0.0 2.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001285540.1_09025001_1 - 0.00038 19.9 8.8 0.012 15.0 0.5 3.8 3 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.31 001285540.1_09025001_1 - 0.0043 17.2 42.0 4.2 8.1 0.2 10.4 10 1 0 10 10 10 3 Leucine Rich Repeat DUF2618 PF10940.6 001285540.1_09025001_3 - 0.18 11.5 2.1 2.7 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) PAD PF03068.13 001265783.1_29629001_2 - 1.9e-167 557.0 0.0 2.6e-167 556.6 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.8 001265783.1_29629001_2 - 3.9e-67 224.7 0.0 6.1e-67 224.1 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.8 001265783.1_29629001_2 - 1e-32 112.7 0.0 1.7e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain IRK PF01007.18 001173120.2_09925001_3 - 2.3e-143 476.9 0.0 3.1e-143 476.6 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.14 001173120.2_09925001_3 - 0.0047 16.8 0.3 0.0047 16.8 0.3 2.4 2 0 0 2 2 2 1 Ion channel IL8 PF00048.18 001032878.1_29621001_1 - 8.5e-15 54.5 1.0 1.1e-14 54.2 1.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like GIT_CC PF16559.3 001171390.1_37922001_1 - 0.049 13.6 0.4 0.08 12.9 0.4 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor MAD PF05557.11 001171390.1_37922001_1 - 0.19 9.9 5.3 0.26 9.5 5.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein IRK PF01007.18 001173044.1_09924001_1 - 1.9e-139 464.1 0.2 2.6e-139 463.6 0.2 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.14 001173044.1_09924001_1 - 1.5 8.7 9.7 5.3 7.0 9.7 2.0 1 1 0 1 1 1 0 Ion channel Ribonuclease_3 PF00636.24 001257872.1_29629001_3 - 3.1e-69 230.1 0.0 2e-43 147.2 0.0 3.1 2 1 0 2 2 2 2 Ribonuclease III domain PAZ PF02170.20 001257872.1_29629001_3 - 6.3e-39 132.8 0.6 1.7e-38 131.4 0.2 2.0 2 0 0 2 2 2 1 PAZ domain Dicer_dimer PF03368.12 001257872.1_29629001_3 - 1.3e-24 86.1 0.0 4e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.4 001257872.1_29629001_3 - 7.2e-24 84.3 0.0 2.9e-16 59.7 0.0 3.3 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.29 001257872.1_29629001_3 - 1.5e-17 63.8 0.0 4.7e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.27 001257872.1_29629001_3 - 5.5e-12 45.7 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.13 001257872.1_29629001_3 - 1.8e-11 44.2 0.0 4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.24 001257872.1_29629001_3 - 0.15 12.6 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif UTP15_C PF09384.8 001260832.1_29626001_1 - 4.8e-48 162.6 0.1 6.9e-48 162.1 0.1 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.30 001260832.1_29626001_1 - 1.4e-27 95.3 1.8 1.4e-06 28.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001260832.1_29626001_1 - 1.2e-09 38.2 0.0 0.0053 16.9 0.0 4.4 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.4 001260832.1_29626001_1 - 0.089 13.2 0.1 27 5.3 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain Repressor_Mnt PF11423.6 001260832.1_29626001_2 - 0.044 13.4 0.4 0.094 12.4 0.4 1.5 1 0 0 1 1 1 0 Regulatory protein Mnt Spectrin PF00435.19 001266968.2_29629001_1 - 0 1058.2 195.6 3.4e-27 94.9 3.3 18.6 19 0 0 19 19 19 17 Spectrin repeat CH PF00307.29 001266968.2_29629001_1 - 1.3e-52 176.4 1.3 7.3e-26 90.4 0.1 3.5 3 0 0 3 3 3 2 Calponin homology (CH) domain PH_9 PF15410.4 001266968.2_29629001_1 - 5.3e-22 78.3 0.7 3.4e-21 75.7 0.7 2.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.27 001266968.2_29629001_1 - 2.6e-17 63.1 0.4 1.8e-16 60.4 0.4 2.6 1 0 0 1 1 1 1 PH domain CAMSAP_CH PF11971.6 001266968.2_29629001_1 - 2.5e-09 36.7 0.2 1.6e-06 27.8 0.1 3.1 2 0 0 2 2 2 2 CAMSAP CH domain CENP-K PF11802.6 001266968.2_29629001_1 - 0.0033 16.9 1.0 0.0033 16.9 1.0 8.4 4 2 4 9 9 9 1 Centromere-associated protein K PH_11 PF15413.4 001266968.2_29629001_1 - 0.0043 17.3 1.8 0.042 14.1 1.8 2.9 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1843 PF08898.8 001266968.2_29629001_1 - 0.76 10.2 4.6 21 5.6 0.0 4.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) RRM_1 PF00076.20 001193845.1_29627001_2 - 1e-43 146.8 1.2 2.8e-15 55.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001193845.1_29627001_2 - 3.9e-06 26.4 0.0 0.00043 19.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001193845.1_29627001_2 - 1.7e-05 24.7 0.0 2.6 8.1 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.6 001193845.1_29627001_2 - 0.0079 16.1 0.1 1.1 9.3 0.1 2.9 3 0 0 3 3 3 1 Limkain b1 RRM_occluded PF16842.3 001193845.1_29627001_2 - 0.049 13.4 0.1 0.27 11.0 0.0 2.3 3 0 0 3 3 3 0 Occluded RNA-recognition motif DEAD PF00270.27 001261317.1_29626001_2 - 1.2e-49 168.4 0.0 2.8e-49 167.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001261317.1_29626001_2 - 1.3e-30 105.9 0.3 6.1e-30 103.7 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001261317.1_29626001_2 - 0.00099 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cadherin PF00028.15 001257905.1_29626001_3 - 2.4e-80 265.0 1.0 2.8e-17 62.8 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.15 001257905.1_29626001_3 - 2.5e-53 179.8 0.7 5.2e-53 178.7 0.0 1.9 2 1 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_2 PF08266.10 001257905.1_29626001_3 - 0.00031 20.4 0.0 0.88 9.3 0.0 3.6 3 0 0 3 3 3 2 Cadherin-like Torsin PF06309.9 001257748.1_29623001_1 - 1.6e-49 167.1 0.1 2.4e-49 166.5 0.1 1.3 1 0 0 1 1 1 1 Torsin AAA PF00004.27 001257748.1_29623001_1 - 5.4e-05 23.5 0.0 8.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.16 001257748.1_29623001_1 - 0.0058 16.3 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.12 001257748.1_29623001_1 - 0.0091 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.4 001257748.1_29623001_1 - 0.018 15.2 0.0 0.45 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.20 001195316.1_39521001_1 - 2.9e-18 65.3 0.0 4.2e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001195316.1_39521001_1 - 0.00067 19.1 0.0 0.00091 18.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001195316.1_39521001_1 - 0.086 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif Cullin_binding PF03556.13 001257454.1_29627001_3 - 7.2e-36 123.1 0.8 7.2e-36 123.1 0.8 1.9 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.4 001257454.1_29627001_3 - 8.9e-10 38.1 0.1 2.5e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 UBA-like domain Piwi PF02171.15 001194973.1_49826001_1 - 2e-108 362.0 0.0 3.2e-108 361.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.20 001194973.1_49826001_1 - 1e-36 125.7 0.2 1.9e-36 124.7 0.2 1.5 1 0 0 1 1 1 1 PAZ domain GAGE PF05831.9 001194973.1_49826001_1 - 4.2e-22 78.6 3.4 4.2e-22 78.6 3.4 1.7 2 0 0 2 2 2 1 GAGE protein ArgoL1 PF08699.8 001194973.1_49826001_1 - 7.3e-06 25.4 0.0 2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.3 001194973.1_49826001_1 - 3.8e-05 24.3 0.0 0.00014 22.5 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute YL1 PF05764.11 001266143.1_29623001_1 - 2.8e-53 181.4 14.7 3.6e-53 181.0 14.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.9 001266143.1_29623001_1 - 1.6e-12 46.8 0.6 3.6e-12 45.7 0.6 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Osteopontin PF00865.16 001266143.1_29623001_1 - 7.6 5.8 13.5 1.2 8.4 9.4 1.6 1 1 1 2 2 2 0 Osteopontin Pkinase PF00069.23 001260959.2_29625001_2 - 9.9e-73 244.6 0.0 1.2e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001260959.2_29625001_2 - 2.3e-34 118.7 0.0 3.2e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001260959.2_29625001_2 - 4.9e-08 32.5 0.1 2.4e-07 30.3 0.0 1.8 1 1 0 2 2 2 1 Kinase-like MARVEL PF01284.21 001260694.1_29623001_1 - 3.8e-17 62.5 15.7 5.8e-17 61.9 15.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain Grp1_Fun34_YaaH PF01184.17 001260694.1_29623001_1 - 0.26 10.7 8.5 0.41 10.1 8.5 1.3 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Pkinase PF00069.23 214193.1_49824001_2 - 1.2e-74 250.8 0.0 1.9e-74 250.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.8 214193.1_49824001_2 - 6.1e-60 200.9 0.0 1e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.15 214193.1_49824001_2 - 1.4e-34 119.4 0.0 3e-34 118.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase SnoaL_3 PF13474.4 214193.1_49824001_2 - 7.6e-11 42.2 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.4 214193.1_49824001_2 - 8.8e-10 38.8 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) APH PF01636.21 214193.1_49824001_2 - 0.0039 17.0 0.1 0.97 9.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.12 214193.1_49824001_2 - 0.0062 15.8 0.2 0.015 14.5 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL_2 PF12680.5 214193.1_49824001_2 - 0.031 14.8 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain FTA2 PF13095.4 214193.1_49824001_2 - 0.095 12.2 0.1 5.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.20 214193.1_49824001_2 - 0.11 11.9 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.20 001246649.1_39724001_3 - 3.6e-22 77.8 0.1 5.6e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM1CTR PF08081.9 001246649.1_39724001_3 - 7.9e-18 64.1 15.7 7.9e-18 64.1 15.7 7.6 6 2 2 8 8 8 1 RBM1CTR (NUC064) family RRM_7 PF16367.3 001246649.1_39724001_3 - 0.0028 17.6 0.0 0.0076 16.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif BNIP3 PF06553.10 001283691.1_29523001_1 - 1.2e-83 279.5 3.7 1.6e-83 279.1 3.7 1.1 1 0 0 1 1 1 1 BNIP3 DUF3319 PF11782.6 001283691.1_29523001_1 - 0.059 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) dsrm PF00035.24 001260847.1_29624001_1 - 8.7e-32 109.5 0.3 3.8e-13 49.8 0.0 3.4 3 0 0 3 3 3 3 Double-stranded RNA binding motif Staufen_C PF16482.3 001260847.1_29624001_1 - 4.7e-09 36.3 0.4 5.6e-07 29.6 0.0 3.0 2 1 1 3 3 3 1 Staufen C-terminal domain DND1_DSRM PF14709.5 001260847.1_29624001_1 - 1.8e-07 31.2 1.4 0.0052 16.9 0.2 3.8 3 1 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 APO_RNA-bind PF05634.9 001260847.1_29624001_1 - 0.00075 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 APO RNA-binding Rhomboid PF01694.20 001261549.1_29623001_3 - 1.1e-29 103.2 15.1 3.1e-28 98.5 14.8 2.2 2 0 0 2 2 2 2 Rhomboid family EKLF_TAD1 PF16832.3 001194455.1_29624001_1 - 2e-17 62.6 7.2 9.4e-17 60.4 7.2 2.3 1 0 0 1 1 1 1 Erythroid krueppel-like transcription factor, transactivation 1 zf-C2H2 PF00096.24 001194455.1_29624001_1 - 9.7e-16 57.1 20.2 3.2e-05 24.0 2.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type EKLF_TAD2 PF16833.3 001194455.1_29624001_1 - 1.2e-15 57.0 5.6 2.4e-15 56.1 5.6 1.5 1 0 0 1 1 1 1 Erythroid krueppel-like transcription factor, transactivation 2 zf-H2C2_2 PF13465.4 001194455.1_29624001_1 - 3.5e-11 42.9 7.1 1.3e-07 31.6 1.6 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001194455.1_29624001_1 - 2.8e-08 33.8 18.6 0.0051 17.4 1.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.5 001194455.1_29624001_1 - 0.014 15.7 6.7 0.82 10.0 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.3 001194455.1_29624001_1 - 0.047 14.2 4.9 1.6 9.3 0.3 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.6 001194455.1_29624001_1 - 0.051 13.8 1.6 2.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.3 001194455.1_29624001_1 - 2.6 8.2 6.7 0.96 9.7 3.8 1.8 2 0 0 2 2 2 0 C2H2-type zinc ribbon Pkinase PF00069.23 001261134.1_29629001_1 - 3.9e-63 213.1 0.0 3.9e-63 213.1 0.0 2.9 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.15 001261134.1_29629001_1 - 2.8e-30 105.3 0.0 8.2e-30 103.8 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Rho_Binding PF08912.9 001261134.1_29629001_1 - 2.5e-22 79.3 16.5 2.5e-22 79.3 16.5 12.7 4 3 8 12 12 12 1 Rho Binding PH PF00169.27 001261134.1_29629001_1 - 1.9e-06 28.2 0.3 0.00013 22.3 0.1 2.9 2 0 0 2 2 2 1 PH domain C1_1 PF00130.20 001261134.1_29629001_1 - 0.0025 17.5 8.0 0.0025 17.5 8.0 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.22 001261134.1_29629001_1 - 0.0059 17.1 1.3 0.019 15.5 1.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.21 001261134.1_29629001_1 - 0.01 15.6 2.8 0.037 13.8 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ndc80_HEC PF03801.11 001265902.1_29625001_1 - 6.8e-52 175.0 0.0 2.3e-51 173.3 0.0 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family ADIP PF11559.6 001265902.1_29625001_1 - 0.0035 17.3 7.3 0.0035 17.3 7.3 4.8 2 2 2 4 4 4 3 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.19 001265902.1_29625001_1 - 0.009 16.0 1.2 0.009 16.0 1.2 6.7 6 1 1 7 7 7 1 bZIP transcription factor DUF3584 PF12128.6 001265902.1_29625001_1 - 0.012 13.0 46.4 0.009 13.5 21.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SlyX PF04102.10 001265902.1_29625001_1 - 0.023 15.2 4.9 0.023 15.2 4.9 6.2 3 2 2 5 5 5 0 SlyX DUF1664 PF07889.10 001265902.1_29625001_1 - 0.05 13.5 33.3 0.14 12.0 1.2 5.1 2 2 2 5 5 5 0 Protein of unknown function (DUF1664) DUF948 PF06103.9 001265902.1_29625001_1 - 0.35 11.0 17.5 0.067 13.3 0.7 4.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.10 001265902.1_29625001_1 - 0.38 10.0 12.8 0.13 11.5 1.7 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Mce4_CUP1 PF11887.6 001265902.1_29625001_1 - 1.2 8.3 6.3 1.2 8.4 0.7 2.5 2 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative RRF PF01765.17 001265902.1_29625001_1 - 3 7.7 31.5 0.15 11.9 2.9 3.8 3 1 0 3 3 3 0 Ribosome recycling factor Ribosomal_S6 PF01250.15 001265902.1_29625001_1 - 5 7.3 8.0 1.9 8.6 0.7 3.4 4 0 0 4 4 4 0 Ribosomal protein S6 HrpB7 PF09486.8 001265902.1_29625001_1 - 5.5 7.2 35.9 0.021 15.1 6.6 4.3 2 2 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) GABP-alpha PF11620.6 001265902.1_29625001_1 - 9.1 6.4 10.8 8 6.6 0.8 3.3 3 0 0 3 3 2 0 GA-binding protein alpha chain RPW8 PF05659.9 001265902.1_29625001_1 - 9.6 5.8 19.1 0.16 11.5 1.1 3.6 3 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spc7 PF08317.9 001265902.1_29625001_1 - 9.9 4.8 63.6 0.56 8.9 17.2 4.0 2 2 2 4 4 4 0 Spc7 kinetochore protein Iso_dh PF00180.18 001265779.2_29625001_3 - 2.3e-77 260.4 0.0 2.9e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Nramp PF01566.16 001284816.1_29525001_3 - 4.4e-119 397.5 13.5 4.4e-119 397.5 13.5 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Renin_r PF07850.12 001284816.1_29525001_3 - 3.3 8.2 0.0 3.3 8.2 0.0 3.1 3 0 0 3 3 3 0 Renin receptor-like protein LRR_8 PF13855.4 001279539.1_24225001_1 - 1.8e-23 81.9 40.5 1.9e-12 46.6 4.2 6.6 3 2 2 6 6 6 5 Leucine rich repeat TIR PF01582.18 001279539.1_24225001_1 - 2.5e-23 82.6 0.3 4.6e-23 81.8 0.3 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001279539.1_24225001_1 - 2.4e-16 59.4 46.5 1.9e-06 27.9 0.4 8.3 4 3 4 9 9 9 8 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001279539.1_24225001_1 - 2.3e-07 31.0 0.0 4.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001279539.1_24225001_1 - 3.6e-06 26.5 43.3 1.4 9.5 0.1 12.5 12 1 0 12 12 12 2 Leucine Rich Repeat LRR_6 PF13516.4 001279539.1_24225001_1 - 8.2e-06 25.3 30.3 3.9 7.7 0.0 10.7 11 0 0 11 11 11 4 Leucine Rich repeat LRRCT PF01463.22 001279539.1_24225001_1 - 0.00044 20.4 0.3 0.0046 17.3 0.0 2.8 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.4 001279539.1_24225001_1 - 0.0013 18.1 12.0 0.71 9.2 1.7 3.8 2 1 2 4 4 4 2 Leucine-rich repeat p25-alpha PF05517.10 001194843.1_29623001_1 - 8.8e-65 217.5 5.6 1.1e-64 217.2 5.6 1.1 1 0 0 1 1 1 1 p25-alpha Pro_isomerase PF00160.19 001266543.1_29626001_3 - 7.9e-49 165.8 0.3 4.2e-48 163.5 0.3 2.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.7 001266543.1_29626001_3 - 2.2e-07 30.6 40.8 2.2e-07 30.6 40.8 5.2 2 1 3 5 5 5 1 Nuclear RNA-splicing-associated protein zf-C2H2_assoc3 PF16637.3 001168769.1_40422001_1 - 1.3e-30 105.4 6.7 3.3e-30 104.2 6.2 1.9 2 0 0 2 2 2 1 Putative zinc-finger between two C2H2 zinc-fingers on Patz zf-C2H2_4 PF13894.4 001168769.1_40422001_1 - 8.7e-07 29.1 18.0 0.00094 19.7 0.8 4.7 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.24 001168769.1_40422001_1 - 5.4e-06 26.4 21.9 2.7e-05 24.2 0.8 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 001168769.1_40422001_1 - 0.0032 17.2 0.2 0.0032 17.2 0.2 4.7 5 0 0 5 5 5 1 C2H2-type zinc finger ARS2 PF04959.11 001168769.1_40422001_1 - 0.017 15.4 1.6 0.032 14.5 0.0 2.0 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-H2C2_2 PF13465.4 001168769.1_40422001_1 - 0.12 12.7 0.8 0.12 12.7 0.8 5.2 5 1 0 5 5 5 0 Zinc-finger double domain zf-C2H2_11 PF16622.3 001168769.1_40422001_1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.6 001168769.1_40422001_1 - 0.13 12.5 7.6 10 6.4 0.3 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.10 001168769.1_40422001_1 - 0.2 11.8 16.4 0.59 10.3 2.1 3.2 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.5 001168769.1_40422001_1 - 0.59 10.5 11.7 4.5 7.7 0.0 4.6 4 1 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.3 001168769.1_40422001_1 - 1.2 8.9 4.8 22 4.8 0.7 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Sgf11 PF08209.9 001168769.1_40422001_1 - 1.5 8.3 6.2 3.3 7.2 0.0 3.5 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Endonuclease_7 PF02945.13 001168769.1_40422001_1 - 1.8 8.4 7.3 2.1 8.2 6.4 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII zf-RVT PF13966.4 001168769.1_40422001_1 - 5.1 7.9 6.2 28 5.5 0.8 2.3 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase zf-HIT PF04438.14 001168769.1_40422001_1 - 9.1 6.1 19.4 3.2 7.6 0.2 4.3 4 0 0 4 4 4 0 HIT zinc finger 7tm_1 PF00001.19 001173108.1_09924001_1 - 2.9e-75 252.9 4.3 3.8e-75 252.4 4.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001173108.1_09924001_1 - 7.1e-07 28.7 4.8 7.1e-07 28.7 4.8 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001173108.1_09924001_1 - 0.00021 21.0 9.9 0.00052 19.7 3.1 2.3 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srbc PF10316.7 001173108.1_09924001_1 - 0.0015 18.0 10.2 0.0015 18.0 10.2 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.7 001173108.1_09924001_1 - 0.094 11.9 16.1 0.0085 15.3 9.7 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx CAF1C_H4-bd PF12265.6 001261191.1_29624001_1 - 3.6e-26 91.1 0.9 1.5e-25 89.0 0.5 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.30 001261191.1_29624001_1 - 4.2e-25 87.4 14.9 2.8e-06 27.8 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001261191.1_29624001_1 - 0.00011 22.2 0.7 0.02 15.0 0.0 3.2 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-met PF12874.5 001285209.1_29525001_2 - 5.4e-25 86.9 23.1 6.8e-07 29.3 1.6 4.5 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001285209.1_29525001_2 - 4.9e-22 77.6 16.7 1.9e-06 27.9 0.2 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.5 001285209.1_29525001_2 - 3.1e-05 24.1 12.3 0.076 13.2 0.6 4.2 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.10 001285209.1_29525001_2 - 0.00031 20.3 19.4 0.019 14.6 0.2 4.4 5 0 0 5 5 5 2 U1 zinc finger DUF3449 PF11931.6 001285209.1_29525001_2 - 0.014 15.0 2.4 0.085 12.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.4 001285209.1_29525001_2 - 0.04 14.6 11.9 0.86 10.5 0.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger CTU2 PF10288.7 001285209.1_29525001_2 - 6.2 7.0 8.4 23 5.1 0.5 3.4 2 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C2H2_6 PF13912.4 001285209.1_29525001_2 - 7.5 6.5 9.9 5.3 7.0 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Zona_pellucida PF00100.21 001267738.1_08025001_1 - 9.5e-50 169.6 1.3 2e-49 168.5 0.7 1.9 2 0 0 2 2 2 1 Zona pellucida-like domain Trypsin PF00089.24 001168975.1_40423001_1 - 6.9e-58 195.9 0.0 9.6e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin Gla PF00594.18 001168975.1_40423001_1 - 1.3e-18 66.7 5.7 2.1e-18 66.1 4.7 1.8 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1986 PF09342.9 001168975.1_40423001_1 - 3e-09 37.1 0.0 5.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) FXa_inhibition PF14670.4 001168975.1_40423001_1 - 2.9e-08 33.7 8.9 2.9e-08 33.7 8.9 2.9 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF PF00008.25 001168975.1_40423001_1 - 1.1e-06 28.7 6.2 1.1e-06 28.7 6.2 2.9 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.5 001168975.1_40423001_1 - 0.003 18.0 3.2 0.003 18.0 3.2 3.1 2 1 0 2 2 2 1 Human growth factor-like EGF cEGF PF12662.5 001168975.1_40423001_1 - 0.0047 16.7 1.5 0.0047 16.7 1.5 3.8 4 1 0 4 4 4 1 Complement Clr-like EGF-like Trypsin_2 PF13365.4 001168975.1_40423001_1 - 0.1 13.3 0.1 0.21 12.3 0.1 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain EGF_2 PF07974.11 001168975.1_40423001_1 - 1.9 8.8 25.3 0.053 13.8 9.9 3.1 2 0 0 2 2 2 0 EGF-like domain G-alpha PF00503.18 001123116.1_49823001_1 - 2.7e-126 421.4 1.8 3.1e-126 421.2 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001123116.1_49823001_1 - 1.2e-17 63.8 0.5 8.9e-13 47.9 0.1 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001123116.1_49823001_1 - 9.5e-06 25.0 1.4 0.032 13.5 0.8 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.11 001123116.1_49823001_1 - 7.9e-05 22.8 0.1 0.59 10.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.4 001123116.1_49823001_1 - 0.022 15.0 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF261 PF03196.11 001123116.1_49823001_1 - 0.024 14.6 0.3 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF261 Ras PF00071.20 001123116.1_49823001_1 - 0.058 12.9 1.7 4.3 6.8 0.9 2.5 2 1 0 2 2 2 0 Ras family TniB PF05621.9 001123116.1_49823001_1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.4 001123116.1_49823001_1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UQ_con PF00179.24 001163058.1_39521001_1 - 6.7e-48 161.8 0.0 7.6e-48 161.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001163058.1_39521001_1 - 0.00077 19.0 0.0 0.00097 18.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.11 001163058.1_39521001_1 - 0.0038 17.0 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.20 001163058.1_39521001_1 - 0.021 15.0 0.1 0.037 14.2 0.1 1.5 1 1 0 1 1 1 0 RWD domain zf-RING_2 PF13639.4 001168930.1_40428001_1 - 3.2e-06 27.2 11.9 1.5e-05 25.0 11.9 2.3 1 0 0 1 1 1 1 Ring finger domain SWIM PF04434.15 001168930.1_40428001_1 - 0.00011 21.6 0.1 0.00021 20.8 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Pkinase PF00069.23 001168930.1_40428001_1 - 0.00019 20.8 0.1 0.16 11.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain PHD PF00628.27 001168930.1_40428001_1 - 0.016 15.0 8.8 0.043 13.6 8.8 1.8 1 0 0 1 1 1 0 PHD-finger Phostensin_N PF13916.4 001168930.1_40428001_1 - 0.031 14.5 0.3 0.1 12.8 0.3 1.9 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal zf-ANAPC11 PF12861.5 001168930.1_40428001_1 - 0.12 12.3 4.3 0.32 11.0 4.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.10 001168930.1_40428001_1 - 0.69 10.1 6.0 4 7.7 2.0 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FANCL_C PF11793.6 001168930.1_40428001_1 - 0.83 9.7 11.2 0.29 11.2 7.7 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain zf-rbx1 PF12678.5 001168930.1_40428001_1 - 1.7 8.9 10.8 8.7 6.6 10.8 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain Pkinase PF00069.23 001265989.1_29624001_3 - 9.9e-78 261.0 0.0 1.3e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001265989.1_29624001_3 - 5.6e-37 127.3 0.0 8e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.27 001265989.1_29624001_3 - 1.5e-17 63.9 0.0 2.9e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.4 001265989.1_29624001_3 - 6.9e-10 38.6 0.0 3.4e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.22 001265989.1_29624001_3 - 1.7e-08 34.9 0.8 4e-08 33.7 0.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.4 001265989.1_29624001_3 - 0.21 11.9 0.5 1.4 9.2 0.5 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain adh_short PF00106.23 001284145.1_29522001_1 - 1e-47 162.0 1.1 1.2e-47 161.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001284145.1_29522001_1 - 2.8e-41 141.5 0.1 3.4e-41 141.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001284145.1_29522001_1 - 1.2e-12 47.9 2.1 2.5e-12 46.9 2.1 1.4 1 1 0 1 1 1 1 KR domain LEH PF07858.10 001284145.1_29522001_1 - 0.14 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Axin_b-cat_bind PF08833.8 001284145.1_29522001_3 - 0.022 14.7 1.3 0.043 13.8 0.4 2.0 2 0 0 2 2 2 0 Axin beta-catenin binding domain LRR_8 PF13855.4 001305889.1_29725001_1 - 3.9e-41 138.5 66.3 4.3e-11 42.3 0.4 10.5 5 4 7 12 12 12 11 Leucine rich repeat TIR PF01582.18 001305889.1_29725001_1 - 2.5e-33 115.2 0.8 4.2e-33 114.5 0.8 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001305889.1_29725001_1 - 9.2e-27 92.4 59.2 1.3e-05 25.2 4.8 11.8 7 2 6 13 13 13 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001305889.1_29725001_1 - 3.8e-10 39.4 20.2 3.7e-05 23.1 0.0 5.1 3 2 2 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.31 001305889.1_29725001_1 - 6.2e-10 38.0 52.5 0.17 12.4 0.1 15.6 14 2 0 14 14 14 3 Leucine Rich Repeat TIR_2 PF13676.4 001305889.1_29725001_1 - 2.5e-09 37.2 0.1 4.7e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001305889.1_29725001_1 - 8.5e-07 28.4 49.8 0.3 11.1 1.6 13.1 15 0 0 15 15 15 3 Leucine Rich repeat DUF1863 PF08937.9 001305889.1_29725001_1 - 0.00012 22.2 0.5 0.00055 20.1 0.5 2.0 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) Curto_V2 PF07325.9 001305889.1_29725001_1 - 0.16 11.7 0.3 0.46 10.2 0.3 1.7 1 0 0 1 1 1 0 Curtovirus V2 protein Fringe PF02434.14 001265731.1_29629001_2 - 0.15 11.3 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Fringe-like MYT1 PF08474.9 001265731.1_29629001_3 - 5.4e-119 396.3 8.0 5.4e-119 396.3 8.0 3.3 2 1 0 2 2 2 1 Myelin transcription factor 1 zf-C2HC PF01530.16 001265731.1_29629001_3 - 3.7e-85 279.6 88.3 1.6e-15 56.9 7.2 7.5 7 0 0 7 7 7 6 Zinc finger, C2HC type DivIC PF04977.13 001265731.1_29629001_3 - 0.23 11.1 12.5 0.74 9.5 2.8 2.8 1 1 1 2 2 2 0 Septum formation initiator DUF1664 PF07889.10 001265731.1_29629001_3 - 0.26 11.2 4.0 0.58 10.0 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Peptidase_Prp PF04327.10 001265731.1_29629001_3 - 0.61 10.2 0.0 0.61 10.2 0.0 2.9 2 1 0 2 2 2 0 Cysteine protease Prp APG6 PF04111.10 001265731.1_29629001_3 - 1.4 8.1 40.2 0.0084 15.4 7.5 2.9 3 0 0 3 3 3 0 Autophagy protein Apg6 bZIP_1 PF00170.19 001265731.1_29629001_3 - 3.4 7.7 12.1 2.6 8.1 3.6 3.0 1 1 1 2 2 2 0 bZIP transcription factor Anti-TRAP PF15777.3 001265731.1_29629001_3 - 7.7 6.4 27.4 1.2 9.0 0.2 6.4 6 0 0 6 6 6 0 Tryptophan RNA-binding attenuator protein inhibitory protein IL8 PF00048.18 001032876.1_29621001_1 - 8.8e-05 22.4 0.1 0.00012 22.0 0.1 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Pkinase PF00069.23 001265631.1_29629001_1 - 2.9e-61 207.0 0.0 4e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.16 001265631.1_29629001_1 - 1.9e-48 162.8 21.1 1.9e-11 44.3 0.0 8.0 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.15 001265631.1_29629001_1 - 1.7e-40 138.9 0.0 2.5e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.4 001265631.1_29629001_1 - 3.9e-32 109.2 22.4 1.2e-08 34.4 0.4 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.4 001265631.1_29629001_1 - 8.2e-05 21.9 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PHD_4 PF16866.3 001160090.1_49829001_3 - 7.7e-22 77.0 12.9 4.3e-21 74.7 12.9 2.4 1 0 0 1 1 1 1 PHD-finger zf-CXXC PF02008.18 001160090.1_49829001_3 - 1.1e-12 47.6 20.8 1.1e-12 47.6 20.8 3.1 3 0 0 3 3 3 1 CXXC zinc finger domain F-box PF00646.31 001160090.1_49829001_3 - 5.8e-09 35.5 4.9 5.8e-09 35.5 4.9 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.5 001160090.1_49829001_3 - 2.7e-08 33.4 6.7 6.9e-08 32.1 6.7 1.8 1 0 0 1 1 1 1 F-box-like JmjC PF02373.20 001160090.1_49829001_3 - 6.5e-06 26.5 0.7 0.00013 22.3 0.7 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.20 001160090.1_49829001_3 - 0.0074 15.8 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 1 Cupin Cupin_8 PF13621.4 001160090.1_49829001_3 - 0.0095 15.6 0.2 0.055 13.1 0.2 2.0 1 1 0 1 1 1 1 Cupin-like domain LRR_6 PF13516.4 001160090.1_49829001_3 - 0.028 14.3 3.9 23 5.2 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich repeat FA_desaturase PF00487.22 001244121.1_49823001_3 - 1e-24 87.6 16.7 1e-24 87.6 16.7 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.8 001244121.1_49823001_3 - 3.9e-20 70.9 0.1 7.6e-20 70.0 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Serpin PF00079.18 001261583.1_29623001_3 - 4.8e-133 443.9 1.4 5.5e-133 443.7 1.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pkinase PF00069.23 001258050.1_29627001_1 - 4.4e-26 91.7 0.0 8.5e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.6 001258050.1_29627001_1 - 1.3e-16 61.4 4.5 5e-09 37.1 0.7 2.4 1 1 1 2 2 2 2 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.15 001258050.1_29627001_1 - 5.1e-14 52.0 0.0 7.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CSD PF00313.20 001256479.1_39522001_1 - 1.2e-16 60.1 0.2 3.4e-16 58.7 0.2 1.8 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.21 001256479.1_39522001_1 - 1.1e-06 28.2 8.7 5.7e-05 22.9 3.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.4 001256479.1_39522001_1 - 0.059 13.0 9.3 0.53 9.9 1.6 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.4 001256479.1_39522001_1 - 0.1 12.3 6.1 1.6 8.5 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle Dishevelled PF02377.13 001256479.1_39522001_2 - 3 8.1 11.8 5.4 7.3 11.8 1.3 1 0 0 1 1 1 0 Dishevelled specific domain Ribosomal_60s PF00428.17 001283165.1_29521001_1 - 8.7e-26 90.2 7.6 8.7e-26 90.2 7.6 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein Type2_restr_D3 PF16902.3 001283165.1_29521001_1 - 0.077 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain adh_short PF00106.23 001257582.1_29624001_3 - 1.6e-46 158.1 0.3 2.2e-46 157.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001257582.1_29624001_3 - 2.8e-29 102.2 0.1 3.8e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001257582.1_29624001_3 - 5.6e-07 29.5 0.3 7.9e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 KR domain OB_NTP_bind PF07717.14 001252212.1_49827001_2 - 5e-27 94.1 0.1 1.1e-26 93.0 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.21 001252212.1_49827001_2 - 6e-24 84.2 0.1 6e-24 84.2 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.29 001252212.1_49827001_2 - 1.1e-12 48.1 0.0 2.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.27 001252212.1_49827001_2 - 1.4e-06 28.0 0.0 3.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.4 001252212.1_49827001_2 - 0.0001 22.5 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.4 001252212.1_49827001_2 - 0.00062 19.9 0.1 0.0037 17.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.20 001252212.1_49827001_2 - 0.0034 16.9 0.0 0.008 15.7 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.13 001252212.1_49827001_2 - 0.0042 17.0 0.0 0.61 9.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.4 001252212.1_49827001_2 - 0.0065 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.4 001252212.1_49827001_2 - 0.022 14.2 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.12 001252212.1_49827001_2 - 0.023 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_29 PF13555.4 001252212.1_49827001_2 - 0.027 14.0 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1777 PF08648.10 001252212.1_49827001_2 - 0.086 13.0 19.2 0.14 12.3 19.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Atrophin-1 PF03154.13 001252212.1_49827001_2 - 0.11 10.7 9.2 0.16 10.1 9.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family AAA_23 PF13476.4 001252212.1_49827001_2 - 0.21 11.9 1.0 0.52 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AF-4 PF05110.11 001252212.1_49827001_2 - 1.7 6.5 9.6 2.2 6.1 9.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DNA_pol_phi PF04931.11 001252212.1_49827001_2 - 7.2 4.5 5.8 11 3.8 5.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF3915 PF13054.4 001252212.1_49827001_2 - 9.4 6.1 13.2 30 4.5 13.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) BTB PF00651.29 001260883.1_29628001_1 - 6.6e-25 87.4 2.8 1.7e-17 63.5 0.5 3.1 2 1 0 2 2 2 2 BTB/POZ domain Ras PF00071.20 001260883.1_29628001_1 - 2.6e-05 23.8 0.0 5.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Ctr PF04145.13 001257506.1_29622001_2 - 8.9e-31 107.4 7.6 8.9e-31 107.4 7.6 1.9 2 1 0 2 2 2 1 Ctr copper transporter family PhoLip_ATPase_C PF16212.3 001169079.1_40427001_1 - 1.7e-77 260.5 31.1 1.7e-77 260.5 31.1 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.3 001169079.1_40427001_1 - 2.9e-23 81.3 0.2 2.9e-23 81.3 0.2 2.3 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.24 001169079.1_40427001_1 - 2.5e-11 44.2 0.1 3e-05 24.3 0.1 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.4 001169079.1_40427001_1 - 3.1e-11 43.1 0.0 6.3e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.18 001169079.1_40427001_1 - 3.2e-11 42.8 1.9 1.6e-10 40.6 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.10 001169079.1_40427001_1 - 0.0023 17.6 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.5 001169079.1_40427001_1 - 0.016 15.5 0.1 0.72 10.1 0.1 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Trypsin PF00089.24 001104585.1_29625001_3 - 4.1e-68 229.4 0.0 5.8e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.16 001104585.1_29625001_3 - 9.1e-50 166.8 10.9 1.7e-25 89.0 3.0 2.5 2 0 0 2 2 2 2 Kringle domain Thrombin_light PF09396.8 001104585.1_29625001_3 - 7.8e-26 89.5 1.0 1.5e-25 88.6 1.0 1.5 1 0 0 1 1 1 1 Thrombin light chain Gla PF00594.18 001104585.1_29625001_3 - 3.3e-18 65.5 5.7 6.6e-18 64.5 5.7 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1986 PF09342.9 001104585.1_29625001_3 - 0.0024 18.1 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001104585.1_29625001_3 - 0.029 15.1 0.0 0.067 13.9 0.0 1.7 1 1 0 1 1 1 0 Trypsin-like peptidase domain CTNNB1_binding PF08347.9 001285746.1_09023001_1 - 2.6e-86 288.8 4.6 2.6e-86 288.8 4.6 1.9 2 0 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.17 001285746.1_09023001_1 - 6.5e-22 77.6 0.7 6.5e-22 77.6 0.7 2.5 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001285746.1_09023001_1 - 1.2e-08 35.3 3.3 2.1e-08 34.5 0.8 2.3 2 0 0 2 2 2 1 HMG-box domain DUF1708 PF08101.9 001285746.1_09023001_3 - 0.04 12.9 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) ERbeta_N PF12497.6 001285688.1_09024001_1 - 2.2e-51 172.3 5.0 4.2e-51 171.4 5.0 1.5 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.28 001285688.1_09024001_1 - 4.8e-36 124.2 0.8 6.8e-36 123.7 0.8 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001285688.1_09024001_1 - 1.5e-29 102.1 13.1 1.5e-29 102.1 13.1 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) ASC PF00858.22 001173063.1_09924001_1 - 4.5e-102 341.9 13.4 6.3e-102 341.4 13.4 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF5001 PF16392.3 001173063.1_09924001_1 - 0.19 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF1664 PF07889.10 001266027.1_29627001_3 - 0.086 12.7 17.8 1.7 8.5 5.7 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) UPF0693 PF16088.3 001266027.1_29627001_3 - 1 9.5 5.3 4.6 7.4 5.3 2.1 1 1 0 1 1 1 0 UPF0693 family THOC7 PF05615.11 001266027.1_29627001_3 - 1 9.5 35.0 0.43 10.7 13.6 3.6 3 1 0 3 3 3 0 Tho complex subunit 7 HLH PF00010.24 001243329.1_49823001_2 - 2.9e-17 62.2 2.9 4.9e-17 61.5 2.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.11 001243329.1_49823001_2 - 2.9e-14 52.8 0.1 5.7e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Hairy Orange dCache_2 PF08269.9 001243329.1_49823001_2 - 0.037 13.1 0.1 0.05 12.7 0.1 1.1 1 0 0 1 1 1 0 Cache domain HTH_Crp_2 PF13545.4 001243329.1_49823001_2 - 0.21 11.4 1.4 0.5 10.3 1.4 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain zf-CCHC_2 PF13696.4 001258145.1_29629001_1 - 0.46 10.2 7.7 0.36 10.6 1.2 2.9 2 0 0 2 2 2 0 Zinc knuckle Glyco_transf_7N PF13733.4 001258145.1_29629001_2 - 3.2e-59 198.2 0.1 4.8e-59 197.7 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.12 001258145.1_29629001_2 - 9.6e-29 98.7 0.1 1.6e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.7 001258145.1_29629001_2 - 0.0071 15.7 0.0 0.018 14.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 PID PF00640.21 001266106.1_29625001_3 - 5.3e-37 126.8 0.0 2.6e-32 111.7 0.0 2.3 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.24 001266106.1_29625001_3 - 9.2e-05 22.2 2.0 9.2e-05 22.2 2.0 2.1 2 0 0 2 2 2 1 WW domain ANF_receptor PF01094.26 001265785.2_29629001_2 - 1.1e-69 235.1 0.0 1.4e-69 234.7 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001265785.2_29629001_2 - 4.3e-59 198.5 0.1 7.7e-59 197.7 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001265785.2_29629001_2 - 5.3e-44 148.9 0.0 1e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001265785.2_29629001_2 - 3.9e-23 81.9 0.0 7.3e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.4 001265785.2_29629001_2 - 0.093 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF659 PF04937.13 001265785.2_29629001_2 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) AAA_23 PF13476.4 001169034.1_40428001_1 - 1.3e-33 117.1 1.4 1.3e-33 117.1 1.4 9.7 2 1 4 7 7 7 1 AAA domain Rad50_zn_hook PF04423.12 001169034.1_40428001_1 - 1.5e-12 47.0 0.1 1.5e-12 47.0 0.1 7.9 8 0 0 8 8 8 1 Rad50 zinc hook motif AAA_15 PF13175.4 001169034.1_40428001_1 - 2e-10 40.7 3.3 2e-10 40.7 3.3 5.3 1 1 3 5 5 5 1 AAA ATPase domain SMC_N PF02463.17 001169034.1_40428001_1 - 7.9e-06 25.3 0.0 7.9e-06 25.3 0.0 3.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.4 001169034.1_40428001_1 - 1e-05 25.6 0.0 3.7e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.4 001169034.1_40428001_1 - 1.6e-05 24.7 30.1 2e-05 24.5 0.0 5.8 4 2 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.4 001169034.1_40428001_1 - 0.0035 16.9 0.0 0.0074 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2703 PF10865.6 001169034.1_40428001_1 - 0.017 15.1 0.8 0.017 15.1 0.8 5.8 5 2 3 9 9 9 0 Domain of unknown function (DUF2703) AAA_16 PF13191.4 001169034.1_40428001_1 - 0.25 11.6 0.0 0.25 11.6 0.0 4.8 5 2 0 5 5 5 0 AAA ATPase domain YgbB PF02542.14 001169034.1_40428001_1 - 8.3 6.5 7.2 6.5 6.9 3.2 3.0 2 0 0 2 2 2 0 YgbB family CDI PF02234.17 001142510.1_39524001_2 - 1.4e-13 50.7 0.1 1.4e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor Lipocalin PF00061.21 001287575.1_09021001_1 - 1.7e-15 57.4 1.7 1.8e-15 57.2 1.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001287575.1_09021001_1 - 1.2e-08 34.8 1.7 1.4e-08 34.6 1.7 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_4 PF13648.4 001287575.1_09021001_1 - 0.0029 18.4 1.2 0.0082 17.0 1.2 1.8 1 1 0 1 1 1 1 Lipocalin-like domain Ion_trans_2 PF07885.14 001199790.1_39523001_1 - 2e-38 130.1 19.5 1.5e-19 69.6 10.1 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.29 001199790.1_39523001_1 - 1.1e-06 27.9 8.3 0.0071 15.5 0.0 2.2 2 0 0 2 2 2 2 Ion transport protein SelK_SelG PF10961.6 001199790.1_39523001_1 - 0.27 11.7 6.4 0.2 12.1 3.4 2.4 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Glyco_transf_10 PF00852.17 001283305.1_29524001_3 - 1.6e-34 119.0 0.0 2.2e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.3 001283305.1_29524001_3 - 2.1e-05 24.8 0.0 4.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Jun PF03957.11 001194461.1_29624001_2 - 2.8e-75 253.0 2.4 4.5e-75 252.4 2.4 1.3 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.19 001194461.1_29624001_2 - 2.4e-18 65.8 12.5 3.9e-18 65.2 12.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001194461.1_29624001_2 - 1.4e-08 34.5 9.9 2.8e-08 33.6 9.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001194461.1_29624001_2 - 3.3e-08 33.8 6.4 6e-08 33.0 6.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Jnk-SapK_ap_N PF09744.7 001194461.1_29624001_2 - 0.024 14.7 1.0 0.036 14.2 1.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ZapB PF06005.10 001194461.1_29624001_2 - 0.028 14.7 0.9 0.028 14.7 0.9 1.7 2 0 0 2 2 2 0 Cell division protein ZapB MAD PF05557.11 001194461.1_29624001_2 - 0.055 11.7 4.0 0.074 11.3 4.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein PspA_IM30 PF04012.10 001194461.1_29624001_2 - 0.062 12.7 1.9 0.095 12.1 1.9 1.2 1 0 0 1 1 1 0 PspA/IM30 family IL8 PF00048.18 001256147.2_49821001_1 - 5.8e-19 67.9 0.1 7.7e-19 67.5 0.1 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Robl_LC7 PF03259.15 001257686.1_29621001_3 - 2.4e-27 94.4 0.0 3.2e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.3 001257686.1_29621001_3 - 0.0054 16.5 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 EGF PF00008.25 001039850.1_32323001_1 - 2.9e-19 68.9 77.8 2.2e-07 30.9 8.3 6.9 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.5 001039850.1_32323001_1 - 2.1e-10 40.7 71.5 0.00016 22.1 3.5 7.8 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.11 001039850.1_32323001_1 - 1.5e-09 37.9 91.7 0.0031 17.7 9.7 6.6 6 0 0 6 6 6 6 EGF-like domain Sid-5 PF17204.1 001039850.1_32323001_1 - 0.11 12.5 0.2 0.26 11.4 0.2 1.6 1 0 0 1 1 1 0 Sid-5 family EGF_CA PF07645.13 001039850.1_32323001_1 - 0.48 10.5 70.1 0.19 11.8 7.6 7.0 4 2 2 6 6 6 0 Calcium-binding EGF domain TNF PF00229.16 001291820.1_09022001_3 - 9.6e-34 115.9 1.4 1.4e-33 115.5 1.4 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Nucleos_tra2_C PF07662.11 001244637.1_49826001_1 - 3.1e-79 265.6 7.3 2.9e-77 259.2 7.7 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.18 001244637.1_49826001_1 - 1.5e-24 86.3 1.5 1.5e-24 86.3 1.5 3.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.12 001244637.1_49826001_1 - 5.7e-08 32.9 6.1 5.7e-08 32.9 6.1 3.5 3 1 0 3 3 3 1 Nucleoside recognition AJAP1_PANP_C PF15298.4 001244637.1_49826001_1 - 0.053 13.6 0.8 0.11 12.5 0.8 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Ras PF00071.20 001261512.2_29623001_1 - 1.2e-57 194.0 0.0 1.5e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001261512.2_29623001_1 - 5.4e-21 74.9 0.0 8.8e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001261512.2_29623001_1 - 6.9e-09 35.3 0.0 9.2e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001261512.2_29623001_1 - 3.5e-06 26.5 0.3 1.5e-05 24.5 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001261512.2_29623001_1 - 3.2e-05 23.7 0.0 0.07 12.9 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001261512.2_29623001_1 - 0.00013 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.14 001261512.2_29623001_1 - 0.011 14.6 0.1 0.088 11.6 0.0 1.9 2 0 0 2 2 2 0 ArgK protein FeoB_N PF02421.16 001261512.2_29623001_1 - 0.027 13.9 0.0 0.12 11.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3953 PF13129.4 001261512.2_29623001_3 - 0.01 15.5 0.2 0.022 14.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) SK_channel PF03530.12 001173122.1_09923001_2 - 5.7e-37 126.1 0.2 1.4e-36 124.8 0.1 1.7 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.14 001173122.1_09923001_2 - 7.7e-26 90.0 5.5 1.5e-25 89.1 5.5 1.5 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.14 001173122.1_09923001_2 - 2.6e-15 56.0 3.4 2.6e-15 56.0 3.4 2.2 2 1 1 3 3 3 1 Ion channel Ion_trans PF00520.29 001173122.1_09923001_2 - 0.00016 20.9 0.3 0.00051 19.2 0.3 1.7 1 1 0 1 1 1 1 Ion transport protein Prefoldin_2 PF01920.18 001173122.1_09923001_2 - 0.093 12.6 0.3 0.093 12.6 0.3 1.8 2 0 0 2 2 2 0 Prefoldin subunit Troponin PF00992.18 001168906.1_40421001_1 - 9.4e-45 152.1 6.7 1.5e-44 151.4 6.7 1.3 1 0 0 1 1 1 1 Troponin DUF2408 PF10303.7 001168906.1_40421001_1 - 0.0021 18.5 3.5 0.0047 17.4 3.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) Tup_N PF08581.8 001168906.1_40421001_1 - 0.0038 17.4 0.8 0.0038 17.4 0.8 2.1 2 0 0 2 2 2 1 Tup N-terminal Transposase_22 PF02994.12 001168906.1_40421001_1 - 0.0075 15.0 2.9 0.0082 14.9 1.4 1.7 1 1 1 2 2 2 1 L1 transposable element DUF919 PF06034.9 001168906.1_40421001_1 - 0.013 15.2 1.1 0.013 15.2 1.1 2.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Cluap1 PF10234.7 001168906.1_40421001_1 - 0.61 9.3 7.8 0.086 12.1 2.7 1.8 1 1 1 2 2 2 0 Clusterin-associated protein-1 Cnn_1N PF07989.9 001168906.1_40421001_1 - 3 7.9 11.1 0.54 10.3 1.2 3.0 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 BST2 PF16716.3 001168906.1_40421001_1 - 4.3 7.9 10.1 1.3 9.5 1.4 2.6 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 IncA PF04156.12 001168906.1_40421001_1 - 7.2 6.2 8.1 23 4.6 8.1 1.9 1 1 0 1 1 1 0 IncA protein Iso_dh PF00180.18 001257762.1_29624001_3 - 9.9e-78 261.6 0.0 1.2e-77 261.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rho_GDI PF02115.15 001168819.1_40422001_1 - 1.5e-57 194.4 0.0 1.8e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Lamp PF01299.15 001244256.1_49823001_2 - 4.6e-119 397.5 12.4 1.3e-116 389.4 7.1 2.0 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.10 001244256.1_49823001_2 - 1.4e-08 34.6 2.0 1.2e-07 31.6 0.1 2.5 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Thioredoxin PF00085.18 001260550.1_29625001_3 - 2.4e-11 43.3 0.0 4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF1510 PF07423.9 001260550.1_29625001_3 - 9.6e-05 21.8 8.7 0.00016 21.1 8.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) FAM176 PF14851.4 001260550.1_29625001_3 - 0.0034 17.0 0.8 0.0034 17.0 0.8 2.3 1 1 1 2 2 2 1 FAM176 family CDC45 PF02724.12 001260550.1_29625001_3 - 0.013 13.7 4.0 0.018 13.3 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4834 PF16118.3 001260550.1_29625001_3 - 0.047 14.5 0.0 0.1 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) IncA PF04156.12 001260550.1_29625001_3 - 0.16 11.6 0.2 0.28 10.8 0.2 1.3 1 0 0 1 1 1 0 IncA protein Nop14 PF04147.10 001260550.1_29625001_3 - 1.7 6.7 22.5 2.2 6.3 22.5 1.0 1 0 0 1 1 1 0 Nop14-like family PIP5K PF01504.16 001244451.1_49827001_3 - 1.5e-91 306.3 0.0 2e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WH1 PF00568.21 001266797.1_29629001_1 - 5.4e-40 135.7 0.2 8.6e-40 135.0 0.2 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.26 001266797.1_29629001_1 - 2.7e-18 66.0 0.0 5.9e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.18 001266797.1_29629001_1 - 5.6e-15 54.5 2.4 1.2e-06 28.0 0.2 2.5 2 0 0 2 2 2 2 WH2 motif EST1_DNA_bind PF10373.7 001260844.1_29629001_3 - 1.6e-39 136.0 4.2 1.2e-32 113.5 1.3 2.3 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.7 001260844.1_29629001_3 - 6.6e-25 88.2 1.6 4e-24 85.6 1.5 2.5 2 0 0 2 2 2 1 Telomerase activating protein Est1 PIN_4 PF13638.4 001260844.1_29629001_3 - 3.8e-06 27.1 0.0 9.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 PIN domain Kunitz_BPTI PF00014.21 001194343.1_29624001_2 - 2.4e-34 117.2 21.0 3.9e-18 65.3 4.6 2.5 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain TIM21 PF08294.9 001193707.1_29623001_3 - 2.1e-47 160.5 0.3 3.2e-47 159.9 0.3 1.3 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.8 001193707.1_29623001_3 - 3.3e-06 26.7 0.0 1.3e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Cullin_binding PF03556.13 001260996.1_29623001_2 - 3e-29 101.7 4.4 4.7e-29 101.1 4.4 1.3 1 0 0 1 1 1 1 Cullin binding Thg1 PF04446.10 001194604.1_29624001_3 - 8.9e-50 167.8 0.4 1.3e-49 167.3 0.4 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.4 001194604.1_29624001_3 - 6.1e-48 161.9 0.0 1e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain HlyIII PF03006.18 001283351.1_29525001_2 - 6.9e-48 163.2 22.5 6.9e-48 163.2 22.5 1.6 2 0 0 2 2 2 1 Haemolysin-III related DUF2207 PF09972.7 001283351.1_29525001_2 - 8.6 4.9 5.5 1.5 7.4 1.5 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) EF-hand_8 PF13833.4 001285572.1_09022001_2 - 1.1e-27 95.5 16.7 4.1e-15 55.1 0.4 3.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.4 001285572.1_09022001_2 - 4.9e-27 94.1 10.0 7e-16 58.3 6.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001285572.1_09022001_2 - 1.3e-25 86.9 24.4 3.5e-08 32.3 1.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.4 001285572.1_09022001_2 - 9.8e-21 71.8 15.5 1.2e-07 31.0 0.4 5.0 3 1 2 5 5 5 4 EF-hand domain EF-hand_5 PF13202.4 001285572.1_09022001_2 - 3.8e-15 54.5 20.4 1.7e-06 27.1 0.3 5.0 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.4 001285572.1_09022001_2 - 7.5e-13 48.5 1.1 4e-06 26.9 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001285572.1_09022001_2 - 1.1e-06 28.4 6.9 0.014 15.2 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001285572.1_09022001_2 - 4.1e-05 23.7 1.7 0.0016 18.6 0.5 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.11 001285572.1_09022001_2 - 0.0024 17.7 0.1 1.5 8.6 0.0 2.3 1 1 0 2 2 2 2 Tellurite resistance protein TerB DUF1707 PF08044.9 001285572.1_09022001_2 - 0.0066 16.4 0.2 1.7 8.7 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1707) UPF0154 PF03672.11 001285572.1_09022001_2 - 0.0084 16.0 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_10 PF14788.4 001285572.1_09022001_2 - 0.034 13.9 4.2 0.11 12.3 0.9 2.8 2 1 1 3 3 3 0 EF hand Dak2 PF02734.15 001285572.1_09022001_2 - 0.058 13.2 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 DAK2 domain DUF1456 PF07308.11 001285572.1_09022001_2 - 0.19 12.0 4.1 3 8.1 0.2 3.1 2 1 1 4 4 3 0 Protein of unknown function (DUF1456) RNA_pol_Rpb4 PF03874.14 001285572.1_09022001_2 - 0.41 10.9 2.6 20 5.4 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb4 Motile_Sperm PF00635.24 001257488.1_29628001_3 - 1.8e-31 108.1 0.1 2.9e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ZapB PF06005.10 001257488.1_29628001_3 - 0.047 14.0 1.3 0.087 13.2 1.3 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Interferon PF00143.17 001278829.1_22422001_1 - 1.2e-60 204.2 7.5 1.4e-60 204.0 7.5 1.1 1 0 0 1 1 1 1 Interferon alpha/beta domain Dna2 PF08696.9 001278829.1_22422001_1 - 0.091 12.4 0.4 0.12 12.1 0.4 1.2 1 0 0 1 1 1 0 DNA replication factor Dna2 ParcG PF10274.7 001278829.1_22422001_1 - 0.2 11.6 1.2 0.89 9.5 1.2 1.9 1 1 0 1 1 1 0 Parkin co-regulated protein Phage_lysis PF03245.11 001278829.1_22422001_3 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Cofilin_ADF PF00241.18 001261155.1_29624001_2 - 7e-16 58.4 0.0 9.2e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pkinase PF00069.23 001260733.1_29629001_3 - 2.1e-64 217.3 0.0 3e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001260733.1_29629001_3 - 2.1e-37 128.7 0.0 3.1e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.20 001260733.1_29629001_3 - 4.4e-32 109.6 26.7 5.7e-16 58.0 4.9 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.28 001260733.1_29629001_3 - 3.7e-28 97.7 0.1 5.9e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.22 001260733.1_29629001_3 - 0.0006 20.3 0.5 0.0016 19.0 0.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.14 001260733.1_29629001_3 - 0.022 14.9 21.2 0.59 10.4 5.4 2.7 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.4 001260733.1_29629001_3 - 1.6 8.2 14.0 3 7.3 1.7 2.9 2 0 0 2 2 2 0 PHD-finger PHD PF00628.27 001260733.1_29629001_3 - 3.3 7.5 21.4 1 9.1 4.3 2.7 2 0 0 2 2 2 0 PHD-finger AIMP2_LysRS_bd PF16780.3 001244557.1_49823001_3 - 3.8e-22 77.6 2.5 8.5e-22 76.5 2.5 1.6 1 0 0 1 1 1 1 AIMP2 lysyl-tRNA synthetase binding domain GST_C_3 PF14497.4 001244557.1_49823001_3 - 4e-05 23.6 0.0 0.00019 21.4 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001244557.1_49823001_3 - 5e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001244557.1_49823001_3 - 7.3e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001244557.1_49823001_3 - 0.018 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zn_ribbon_recom PF13408.4 001266307.1_29628001_1 - 0.22 12.0 1.9 0.49 10.8 1.9 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain CH PF00307.29 001266307.1_29628001_3 - 9.4e-89 292.7 2.1 1.1e-24 86.6 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.30 001266307.1_29628001_3 - 9.8e-14 49.7 2.2 1.6e-07 30.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.4 001266307.1_29628001_3 - 1.2e-12 48.0 1.9 2.2e-09 37.5 0.2 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001266307.1_29628001_3 - 6.7e-10 38.0 1.6 5.6e-06 25.8 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.4 001266307.1_29628001_3 - 7e-09 34.7 4.6 0.00026 20.2 0.2 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.4 001266307.1_29628001_3 - 1e-07 31.5 3.2 0.008 15.8 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair CAMSAP_CH PF11971.6 001266307.1_29628001_3 - 0.00036 20.2 0.0 0.00094 18.8 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain TNFR_c6 PF00020.16 001278772.1_09922001_1 - 7.3e-22 77.4 44.9 1.3e-10 41.4 7.2 4.5 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region RRM_1 PF00076.20 001190739.1_29623001_2 - 6.5e-22 77.0 0.0 9.5e-22 76.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001190739.1_29623001_2 - 0.0039 17.0 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Apt1 PF10351.7 001190739.1_29623001_2 - 0.063 12.0 13.2 0.078 11.7 13.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRM_5 PF13893.4 001190739.1_29623001_2 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.5 001166184.1_39523001_2 - 1.7e-28 98.9 0.4 2.8e-11 43.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.28 001166184.1_39523001_2 - 4.3e-28 96.4 5.6 3.6e-07 30.2 0.2 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.4 001166184.1_39523001_2 - 4.6e-24 81.7 4.3 6.8e-06 25.9 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.4 001166184.1_39523001_2 - 1.9e-22 78.9 3.4 2.9e-10 40.1 0.1 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.4 001166184.1_39523001_2 - 1e-20 73.7 0.3 3.3e-09 37.0 0.3 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) G-gamma PF00631.20 001265813.1_29622001_1 - 1.6e-14 53.5 0.0 2.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 GGL domain IRK PF01007.18 001173037.1_09925001_1 - 1.3e-157 523.8 0.1 1.6e-157 523.5 0.1 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK_N PF08466.8 001173037.1_09925001_1 - 2.6e-24 85.0 0.6 5.3e-24 84.0 0.6 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.14 001173037.1_09925001_1 - 0.0021 17.9 1.7 0.0047 16.7 1.7 1.6 1 1 0 1 1 1 1 Ion channel Aph-1 PF06105.10 001266040.1_29624001_2 - 8.3e-93 309.9 14.0 1e-92 309.6 14.0 1.1 1 0 0 1 1 1 1 Aph-1 protein Peptidase_M3_N PF08439.8 001266040.1_29624001_2 - 0.082 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Oligopeptidase F MORN PF02493.18 001194309.1_29623001_2 - 1.3e-35 119.0 37.5 1.8e-08 33.7 2.3 7.6 7 0 0 7 7 7 7 MORN repeat NESP55 PF06390.10 001194309.1_29623001_2 - 0.15 11.5 3.1 0.33 10.4 3.1 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) BORG_CEP PF14957.4 001194619.1_29623001_2 - 7.3e-22 78.6 6.0 1.8e-20 74.1 6.0 2.2 1 1 0 1 1 1 1 Cdc42 effector PBD PF00786.26 001194619.1_29623001_2 - 4.6e-09 36.4 0.1 7.5e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain IL8 PF00048.18 001161434.1_49822001_3 - 7e-22 77.2 1.4 9.5e-22 76.8 1.4 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like ANF_receptor PF01094.26 001261276.1_29629001_1 - 5.1e-71 239.5 0.0 6.7e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.20 001261276.1_29629001_1 - 5.1e-52 176.8 4.1 5.1e-52 176.8 4.1 1.9 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.4 001261276.1_29629001_1 - 1.3e-19 70.9 0.0 2.1e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein NEMP PF10225.7 001261276.1_29629001_1 - 0.025 14.2 0.4 0.076 12.6 0.4 1.8 1 0 0 1 1 1 0 NEMP family Kei1 PF08552.9 001261276.1_29629001_1 - 0.025 14.2 1.0 0.98 8.9 0.1 2.5 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3995 PF13160.4 001261276.1_29629001_1 - 0.043 14.0 0.0 0.043 14.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) PKcGMP_CC PF16808.3 001261276.1_29629001_1 - 0.14 11.9 6.5 0.33 10.7 6.5 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pkinase PF00069.23 001142508.1_39523001_2 - 2.1e-77 260.0 0.0 2.4e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001142508.1_39523001_2 - 5.5e-35 120.8 0.0 6.9e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001142508.1_39523001_2 - 0.0023 17.2 0.0 0.0048 16.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001142508.1_39523001_2 - 0.0098 15.7 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.12 001142508.1_39523001_2 - 0.065 12.4 0.0 0.2 10.9 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAP PF00956.16 001266934.1_29624001_2 - 2.3e-09 36.7 4.6 4.2e-09 35.9 4.6 1.4 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.10 001266934.1_29624001_2 - 0.0054 16.5 5.0 0.011 15.5 5.0 1.5 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Mst1_SARAH PF11629.6 001266934.1_29624001_2 - 0.022 14.7 0.4 0.047 13.6 0.4 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 OmpH PF03938.12 001266934.1_29624001_2 - 0.05 13.5 0.6 0.05 13.5 0.6 1.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Lectin_C PF00059.19 001105535.2_29622001_3 - 2.3e-20 73.2 0.2 4e-20 72.4 0.2 1.4 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.16 001105535.2_29622001_3 - 1.6e-08 34.0 29.4 5e-08 32.5 29.4 1.8 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Granulin PF00396.16 001105535.2_29622001_3 - 0.05 13.8 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Granulin HPS6 PF15702.3 001194529.1_29626001_2 - 2.9e-285 948.2 0.0 3.2e-285 948.0 0.0 1.0 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 6 protein wnt PF00110.17 001265938.2_29623001_1 - 1.2e-121 405.8 21.0 1.4e-121 405.6 21.0 1.0 1 0 0 1 1 1 1 wnt family COG6 PF06419.9 001265938.2_29623001_1 - 0.31 9.1 0.1 0.43 8.6 0.1 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Methyltransf_32 PF13679.4 001266390.1_29626001_1 - 1.2e-09 38.2 5.9 1.8e-08 34.4 5.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.4 001266390.1_29626001_1 - 1.7e-08 34.3 0.0 9e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.13 001266390.1_29626001_1 - 1.1e-05 24.7 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G TRM13 PF05206.12 001266390.1_29626001_1 - 0.00061 19.3 6.3 0.16 11.3 1.3 2.8 2 1 1 3 3 3 2 Methyltransferase TRM13 MTS PF05175.12 001266390.1_29626001_1 - 0.00076 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain GST_C_3 PF14497.4 001266390.1_29626001_1 - 0.00076 19.5 0.1 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.4 001266390.1_29626001_1 - 0.0022 18.6 0.0 0.0049 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GST_C_2 PF13410.4 001266390.1_29626001_1 - 0.0029 17.4 0.1 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ubie_methyltran PF01209.16 001266390.1_29626001_1 - 0.007 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.15 001266390.1_29626001_1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.7 001266390.1_29626001_1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GST_C PF00043.23 001266390.1_29626001_1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Interferon PF00143.17 001135795.1_29622001_1 - 6.6e-58 195.3 3.1 7.8e-58 195.0 3.1 1.1 1 0 0 1 1 1 1 Interferon alpha/beta domain zf-AN1 PF01428.14 001194857.1_29622001_3 - 3.4e-21 75.0 39.3 8.2e-13 48.2 8.1 3.6 3 1 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.13 001194857.1_29622001_3 - 0.026 14.8 6.3 0.026 14.8 6.3 2.8 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain IBR PF01485.19 001194857.1_29622001_3 - 3.1 8.0 32.2 30 4.8 7.5 3.9 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain Cofilin_ADF PF00241.18 001195492.1_29622001_3 - 2.9e-28 98.5 0.2 4e-28 98.0 0.2 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ion_trans_2 PF07885.14 001172763.1_09922001_1 - 8.9e-34 115.2 13.2 8.3e-19 67.2 4.8 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.29 001172763.1_09922001_1 - 1.9e-05 23.9 0.8 0.022 13.8 0.9 2.3 2 1 0 2 2 2 2 Ion transport protein SelB-wing_2 PF09106.9 001172763.1_09922001_1 - 0.046 13.8 0.7 0.11 12.6 0.3 1.8 1 1 1 2 2 2 0 Elongation factor SelB, winged helix DUF2101 PF09874.7 001172763.1_09922001_1 - 0.11 12.1 0.3 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) DUF2070 PF09843.7 001172763.1_09922001_1 - 4.8 5.2 8.9 1.5 6.9 6.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Glyco_hydro_20 PF00728.20 001123221.1_49824001_1 - 9.1e-86 288.3 0.0 1.4e-85 287.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.4 001123221.1_49824001_1 - 9.7e-20 71.4 0.0 1.7e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.13 001123221.1_49824001_1 - 0.01 16.5 0.0 0.047 14.4 0.0 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 TFIIA PF03153.11 001204850.1_32323001_1 - 4.1e-130 435.4 0.6 4.8e-130 435.2 0.6 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FA_desaturase PF00487.22 001266006.1_29623001_1 - 8.3e-25 87.9 15.1 8.3e-25 87.9 15.1 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.8 001266006.1_29623001_1 - 6.7e-21 73.4 0.6 1.3e-20 72.5 0.6 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Scs3p PF10261.7 001194524.1_29623001_3 - 4.7e-12 45.8 21.2 8.9e-05 22.0 6.5 3.1 1 1 0 3 3 3 3 Inositol phospholipid synthesis and fat-storage-inducing TM Ion_trans_2 PF07885.14 001194723.1_29623001_1 - 1.7e-31 107.9 12.8 1.1e-17 63.7 0.4 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.29 001194723.1_29623001_1 - 1.9e-06 27.2 6.3 0.00014 21.0 0.4 2.1 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.18 001194723.1_29623001_1 - 2.9 6.6 5.5 0.3 9.9 0.1 1.9 2 1 0 2 2 2 0 Inward rectifier potassium channel Glyco_transf_29 PF00777.16 001285660.1_09024001_3 - 2.5e-34 118.8 0.0 4.6e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G-alpha PF00503.18 001265908.1_29624001_3 - 3e-114 381.8 4.9 3.6e-114 381.5 4.9 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001265908.1_29624001_3 - 3.7e-14 52.4 3.2 1.4e-10 40.8 0.0 3.2 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001265908.1_29624001_3 - 0.0046 16.2 2.0 0.16 11.2 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Atx10homo_assoc PF09759.7 001265908.1_29624001_3 - 0.046 13.7 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Condensation PF00668.18 001265908.1_29624001_3 - 0.052 12.1 0.3 0.079 11.5 0.3 1.2 1 0 0 1 1 1 0 Condensation domain MMR_HSR1 PF01926.21 001265908.1_29624001_3 - 0.06 13.3 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.11 001265908.1_29624001_3 - 0.069 13.3 0.2 7.8 6.6 0.0 2.7 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Pro_isomerase PF00160.19 001132588.1_43525001_2 - 1.1e-45 155.6 0.1 1.4e-45 155.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BTB PF00651.29 001266985.1_29629001_2 - 4.8e-27 94.3 2.4 5.2e-14 52.3 0.0 3.7 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.20 001266985.1_29629001_2 - 4.4e-23 81.5 0.0 7.4e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001266985.1_29629001_2 - 6.1e-09 36.0 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase YL1 PF05764.11 001168948.1_40423001_1 - 1.8e-53 182.0 14.7 2.4e-53 181.6 14.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.9 001168948.1_40423001_1 - 1.5e-12 46.9 0.6 2.9e-12 46.0 0.6 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Osteopontin PF00865.16 001168948.1_40423001_1 - 8 5.7 14.0 1.1 8.6 9.6 1.6 1 1 1 2 2 2 0 Osteopontin zf-DHHC PF01529.18 001194087.1_29629001_2 - 5.8e-34 116.9 20.4 5.8e-34 116.9 20.4 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase TEA PF01285.16 001037966.1_49823001_1 - 4.6e-26 91.8 0.1 1.2e-25 90.4 0.0 1.6 2 0 0 2 2 2 1 TEA/ATTS domain family Tom7 PF08038.10 001265860.1_29621001_3 - 2.3e-14 52.6 0.0 3.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 TOM7 family SWIM PF04434.15 001265702.1_29621001_2 - 6.3e-09 35.2 3.9 1.2e-08 34.3 3.9 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF1294 PF06961.11 001265702.1_29621001_2 - 0.18 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Pkinase PF00069.23 001319386.1_29524001_3 - 4.2e-56 190.1 0.0 4.2e-56 190.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001319386.1_29524001_3 - 4.4e-21 75.2 0.0 7.9e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001319386.1_29524001_3 - 0.0039 16.4 0.1 0.0076 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001319386.1_29524001_3 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L7Ae PF01248.24 001258064.2_29629001_1 - 7.5e-22 76.7 0.2 3.6e-21 74.6 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metallophos PF00149.26 214128.1_49825001_2 - 1.1e-38 133.7 0.1 1.8e-38 133.0 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HLH PF00010.24 001194446.1_29622001_2 - 3.2e-16 58.9 0.3 4.6e-16 58.4 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.3 001194446.1_29622001_2 - 0.037 13.6 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain zf-FCS PF06467.12 001265737.1_29629001_3 - 2.6e-70 232.0 117.1 1.6e-10 40.7 4.1 10.7 10 0 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif DUF3504 PF12012.6 001265737.1_29629001_3 - 7.2e-63 211.2 1.8 2.3e-62 209.5 1.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Arc_trans_TRASH PF08394.8 001265737.1_29629001_3 - 0.0015 18.7 5.6 0.0015 18.7 5.6 7.2 8 0 0 8 8 8 1 Archaeal TRASH domain YHS PF04945.11 001265737.1_29629001_3 - 0.0051 16.8 0.2 0.0051 16.8 0.2 9.5 10 0 0 10 10 10 3 YHS domain Ribosomal_L24e PF01246.18 001265737.1_29629001_3 - 0.024 14.7 0.2 0.024 14.7 0.2 7.2 7 1 1 8 8 8 0 Ribosomal protein L24e NosL PF05573.10 001265737.1_29629001_3 - 0.062 13.3 3.1 5.4 7.0 0.1 3.7 2 1 1 3 3 3 0 NosL Pkinase PF00069.23 001168870.1_40424001_1 - 5.4e-61 206.1 0.0 6.8e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001168870.1_40424001_1 - 1.5e-32 112.8 0.0 2.5e-32 112.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.28 001168870.1_40424001_1 - 3.1e-28 97.9 0.0 4.8e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.22 001168870.1_40424001_1 - 5.8e-07 30.0 0.3 1.7e-06 28.5 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_1 PF00130.20 001168870.1_40424001_1 - 0.00032 20.4 5.4 0.00059 19.5 5.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.4 001168870.1_40424001_1 - 0.043 13.0 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.21 001168870.1_40424001_1 - 0.067 13.0 0.2 0.2 11.4 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family NPDC1 PF06809.9 001283783.1_29523001_1 - 3.9e-189 627.7 26.3 1.4e-188 625.9 26.3 1.8 1 1 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) AA_permease PF00324.19 001009756.1_39527001_1 - 1.7e-64 218.0 35.9 5.2e-39 134.0 6.5 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.13 001009756.1_39527001_1 - 1.2e-47 162.7 4.0 1e-29 103.7 2.5 3.0 1 1 1 2 2 2 2 Solute carrier family 12 Aldo_ket_red PF00248.19 001243822.1_49823001_1 - 6.6e-52 176.3 0.0 8.4e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IL8 PF00048.18 001009580.1_49821001_3 - 1.7e-07 31.1 1.3 2.7e-07 30.5 1.3 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like XRCC4 PF06632.10 001284064.1_29524001_2 - 3.7e-160 532.2 10.1 4.3e-160 531.9 10.1 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF927 PF06048.9 001284064.1_29524001_2 - 0.03 13.7 0.4 0.046 13.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Cation_efflux PF01545.19 001139475.1_49823001_3 - 8.7e-48 162.6 14.2 1.2e-47 162.2 14.2 1.2 1 0 0 1 1 1 1 Cation efflux family PDR_CDR PF06422.10 001139475.1_49823001_3 - 0.15 11.9 0.1 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 CDR ABC transporter Arf PF00025.19 001261028.1_29622001_1 - 7.5e-62 207.7 0.0 9.3e-62 207.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.18 001261028.1_29622001_1 - 5.7e-09 35.5 0.1 8.6e-07 28.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.8 001261028.1_29622001_1 - 6.9e-09 35.2 0.0 9.2e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.11 001261028.1_29622001_1 - 1.6e-06 28.2 0.0 3e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.21 001261028.1_29622001_1 - 1.2e-05 25.3 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.20 001261028.1_29622001_1 - 1.3e-05 24.8 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.25 001261028.1_29622001_1 - 0.00095 18.6 0.0 0.0085 15.5 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.10 001261028.1_29622001_1 - 0.042 13.1 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Metalloenzyme PF01676.16 001261028.1_29622001_1 - 0.22 10.7 0.0 3.5 6.8 0.0 2.0 1 1 1 2 2 2 0 Metalloenzyme superfamily PTR2 PF00854.19 001009758.1_39526001_2 - 6.4e-146 486.1 13.6 1.1e-134 449.1 11.1 2.3 2 0 0 2 2 2 2 POT family AlgF PF11182.6 001009758.1_39526001_2 - 0.065 12.9 0.6 0.42 10.2 0.1 2.1 1 1 1 2 2 2 0 Alginate O-acetyl transferase AlgF DUF1772 PF08592.9 001009758.1_39526001_2 - 1.3 9.2 4.1 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF2207 PF09972.7 001009758.1_39526001_2 - 6.9 5.2 8.1 7.1 5.1 1.7 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Piwi PF02171.15 001195663.1_29627001_1 - 9.8e-87 290.8 0.1 1.5e-86 290.2 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.20 001195663.1_29627001_1 - 2.9e-34 117.7 0.5 5.2e-34 116.9 0.5 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.8 001195663.1_29627001_1 - 4.9e-09 35.5 0.0 1.5e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.3 001195663.1_29627001_1 - 0.0095 16.5 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute wnt PF00110.17 001170828.1_49827001_2 - 3.8e-48 164.5 6.3 5.3e-48 164.0 6.3 1.1 1 0 0 1 1 1 1 wnt family wnt PF00110.17 001170828.1_49827001_3 - 5.3e-71 239.5 10.8 9.9e-71 238.6 10.8 1.4 1 0 0 1 1 1 1 wnt family PAP2 PF01569.19 001257733.1_29623001_1 - 1.6e-17 63.4 7.9 1.6e-17 63.4 7.9 2.1 2 0 0 2 2 2 1 PAP2 superfamily KH_1 PF00013.27 001244285.1_49827001_1 - 3.7e-68 225.2 14.5 1.4e-18 66.3 0.6 4.2 4 0 0 4 4 4 4 KH domain KH_2 PF07650.15 001244285.1_49827001_1 - 4.6e-20 71.1 8.9 3.7e-05 23.3 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_4 PF13083.4 001244285.1_49827001_1 - 1.8e-10 40.4 8.9 0.083 12.6 0.2 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.8 001244285.1_49827001_1 - 0.00097 18.4 3.1 0.0019 17.5 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) KH_5 PF13184.4 001244285.1_49827001_1 - 0.042 13.8 11.2 5.1 7.1 0.2 4.3 4 0 0 4 4 4 0 NusA-like KH domain Sec3-PIP2_bind PF15277.4 001246666.1_49822001_3 - 1.4e-23 82.7 0.2 2.2e-23 82.1 0.2 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Synaptobrevin PF00957.19 001246666.1_49822001_3 - 1.1e-06 28.2 0.6 1.1e-06 28.2 0.6 1.8 2 0 0 2 2 2 1 Synaptobrevin DUF2761 PF10959.6 001246666.1_49822001_3 - 0.071 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) P4Ha_N PF08336.9 001169033.1_40424001_1 - 3.4e-39 133.8 0.0 6.7e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.4 001169033.1_40424001_1 - 1.6e-15 57.6 0.1 5.4e-14 52.7 0.1 2.7 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.15 001169033.1_40424001_1 - 0.00022 20.9 0.9 0.008 16.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001169033.1_40424001_1 - 0.0093 15.9 0.4 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.4 001169033.1_40424001_1 - 0.0093 16.6 0.1 0.039 14.7 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat SPO22 PF08631.8 001169033.1_40424001_1 - 0.057 12.7 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.5 001169033.1_40424001_1 - 0.089 12.9 0.1 0.32 11.1 0.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SPA PF08616.8 001194565.1_29624001_1 - 3.8e-13 49.3 0.0 6.8e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.19 001194565.1_29624001_1 - 2.3e-07 30.8 5.2 3.1e-07 30.4 2.2 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.7 001194565.1_29624001_1 - 1.7e-06 26.9 0.0 2.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SH3_2 PF07653.15 001257483.1_29625001_1 - 6.2e-24 83.3 0.2 8.1e-12 44.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.22 001257483.1_29625001_1 - 1.9e-21 75.8 0.0 3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.26 001257483.1_29625001_1 - 6.3e-21 73.6 0.3 3e-16 58.6 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 001257483.1_29625001_1 - 1.5e-16 59.8 0.1 4.9e-09 35.8 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.4 001257483.1_29625001_1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Herpes_pp85 PF04637.10 001266943.1_29627001_1 - 0.031 12.6 0.0 0.046 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) COesterase PF00135.26 001177891.1_09924001_3 - 1.7e-172 574.8 0.0 2e-172 574.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family AChE_tetra PF08674.8 001177891.1_09924001_3 - 2.2e-20 71.9 9.4 4e-20 71.1 9.4 1.4 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain Abhydrolase_3 PF07859.11 001177891.1_09924001_3 - 7.8e-06 25.7 0.3 3.2e-05 23.8 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Trypsin PF00089.24 001080136.1_29625001_2 - 7e-58 195.9 0.0 1.7e-57 194.7 0.0 1.7 1 0 0 1 1 1 1 Trypsin Gla PF00594.18 001080136.1_29625001_2 - 4.2e-18 65.1 6.2 4.5e-18 65.0 4.7 1.9 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1986 PF09342.9 001080136.1_29625001_2 - 2.4e-08 34.2 0.1 5.2e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) FXa_inhibition PF14670.4 001080136.1_29625001_2 - 6.1e-08 32.7 8.9 6.1e-08 32.7 8.9 5.7 4 1 0 4 4 4 1 Coagulation Factor Xa inhibitory site EGF PF00008.25 001080136.1_29625001_2 - 2.3e-06 27.7 6.2 2.3e-06 27.7 6.2 5.4 5 1 1 6 6 6 1 EGF-like domain hEGF PF12661.5 001080136.1_29625001_2 - 0.0059 17.1 3.2 0.0059 17.1 3.2 3.1 3 0 0 3 3 3 1 Human growth factor-like EGF cEGF PF12662.5 001080136.1_29625001_2 - 0.0094 15.7 1.5 0.0094 15.7 1.5 3.7 4 0 0 4 4 4 1 Complement Clr-like EGF-like Glycos_transf_4 PF00953.19 001257856.1_29624001_2 - 1.2e-36 126.0 12.9 1.2e-36 126.0 12.9 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 Gal_mutarotas_2 PF13802.4 001257856.1_29624001_2 - 0.14 12.4 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Galactose mutarotase-like DUF4133 PF13571.4 001257856.1_29624001_2 - 3.7 7.8 6.5 0.91 9.8 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Rb_C PF08934.8 001261047.1_29629001_3 - 1.2e-82 274.9 3.5 1.2e-82 274.9 3.5 2.0 2 0 0 2 2 2 1 Rb C-terminal domain RB_A PF01858.15 001261047.1_29629001_3 - 2.5e-75 252.6 0.9 2.5e-75 252.6 0.9 2.0 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.18 001261047.1_29629001_3 - 4.8e-35 120.3 8.8 7.1e-34 116.5 5.9 2.9 3 0 0 3 3 3 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.6 001261047.1_29629001_3 - 7.8e-11 41.5 3.3 7.8e-11 41.5 3.3 3.6 4 1 0 4 4 4 1 Domain of unknown function (DUF3452) DUF4592 PF15262.4 001261047.1_29629001_3 - 4.4 8.1 6.3 36 5.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) Ribosomal_60s PF00428.17 001261047.1_29629001_3 - 6 7.4 5.4 13 6.3 5.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein IL8 PF00048.18 001128491.1_49821001_1 - 2.1e-11 43.7 1.3 3.2e-11 43.1 1.3 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Ion_trans_2 PF07885.14 001261646.1_29625001_1 - 1.9e-30 104.6 18.7 4.7e-15 55.2 7.3 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.29 001261646.1_29625001_1 - 5.6e-05 22.4 10.6 0.0013 17.9 0.1 2.2 2 0 0 2 2 2 2 Ion transport protein DUF21 PF01595.18 001261646.1_29625001_1 - 0.0054 16.3 3.5 1.5 8.4 0.1 2.8 3 1 0 3 3 3 2 Domain of unknown function DUF21 CD20 PF04103.13 001261646.1_29625001_1 - 0.016 15.1 2.7 0.016 15.1 2.7 2.0 2 0 0 2 2 2 0 CD20-like family Presenilin PF01080.15 001261646.1_29625001_1 - 0.67 8.5 6.0 1.1 7.8 6.0 1.4 1 0 0 1 1 1 0 Presenilin GST_N_3 PF13417.4 001284130.1_29525001_2 - 1.9e-10 40.8 0.0 3.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001284130.1_29525001_2 - 9.5e-08 32.2 0.0 3.3e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001284130.1_29525001_2 - 2.5e-07 30.8 0.0 5.9e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001284130.1_29525001_2 - 3.1e-06 26.9 0.0 8.1e-06 25.6 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001284130.1_29525001_2 - 2e-05 24.6 0.0 3.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001284130.1_29525001_2 - 0.0036 17.3 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Nsp1 PF11501.6 001284130.1_29525001_2 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Non structural protein Nsp1 LRR_8 PF13855.4 001257588.1_29628001_2 - 1.6e-50 168.5 79.6 2.5e-11 43.0 6.8 8.8 4 3 3 9 9 9 8 Leucine rich repeat LRR_4 PF12799.5 001257588.1_29628001_2 - 5.9e-35 118.5 78.7 3.6e-06 27.0 0.3 10.7 7 2 5 13 13 13 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001257588.1_29628001_2 - 1.6e-09 37.4 36.9 0.015 14.7 2.2 5.6 2 2 4 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.31 001257588.1_29628001_2 - 0.2 12.1 67.0 4.6 8.0 0.7 16.7 18 1 1 19 19 19 0 Leucine Rich Repeat Lipocalin PF00061.21 001267884.2_39522001_1 - 1.1e-29 103.3 2.2 1.3e-29 103.1 2.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001267884.2_39522001_1 - 1e-08 35.1 1.1 1.3e-08 34.7 1.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family FAM176 PF14851.4 001194534.1_29624001_2 - 2.2e-59 199.2 0.3 2.9e-59 198.7 0.3 1.2 1 0 0 1 1 1 1 FAM176 family zf-RanBP PF00641.16 001257636.1_29626001_3 - 1.3e-12 46.6 22.2 1.5e-06 27.2 3.7 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.6 001257636.1_29626001_3 - 0.39 10.5 5.8 0.73 9.6 0.2 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) LIM PF00412.20 001168749.1_40423001_1 - 2.4e-19 69.2 24.1 1.5e-09 37.8 7.2 3.3 2 1 0 2 2 2 2 LIM domain PET PF06297.12 001168749.1_40423001_1 - 2e-11 43.9 0.1 4e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 PET Domain FGF PF00167.16 001266029.1_29628001_3 - 3e-41 140.3 0.0 4.9e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 001266029.1_29628001_3 - 0.032 14.3 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Fascin domain zf-H2C2_2 PF13465.4 001257795.1_29629001_2 - 1.7e-24 84.9 49.6 1.3e-07 31.6 0.4 8.1 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.24 001257795.1_29629001_2 - 2.5e-23 81.0 49.3 0.00015 21.9 1.3 7.2 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001257795.1_29629001_2 - 4.5e-13 48.7 47.1 0.013 16.1 0.8 7.9 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001257795.1_29629001_2 - 4e-08 33.3 19.2 0.0038 17.4 1.8 3.9 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.6 001257795.1_29629001_2 - 0.00026 21.1 15.4 0.075 13.2 0.8 5.8 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001257795.1_29629001_2 - 0.0013 18.5 25.2 0.072 12.9 0.7 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger Marek_A PF02124.13 001257795.1_29629001_2 - 0.0015 18.3 1.3 1.2 8.7 0.3 2.6 2 1 1 3 3 3 2 Marek's disease glycoprotein A zf-C2H2_aberr PF17017.3 001257795.1_29629001_2 - 2.7 8.0 17.2 7.2 6.6 0.9 5.0 1 1 4 5 5 5 0 Aberrant zinc-finger Mito_carr PF00153.25 001308581.1_39523001_1 - 3.7e-68 225.4 0.9 3e-24 84.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IL8 PF00048.18 001032875.1_29621001_1 - 6.4e-18 64.5 0.1 9.3e-18 64.0 0.1 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like CAF1C_H4-bd PF12265.6 001284176.1_29525001_2 - 1.2e-27 95.8 0.6 4.2e-27 94.1 0.1 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.30 001284176.1_29525001_2 - 7.2e-23 80.3 16.2 6.4e-07 29.8 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001284176.1_29525001_2 - 0.0004 20.5 0.5 0.027 14.6 0.0 3.2 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001284176.1_29525001_2 - 0.0012 18.7 0.6 0.048 13.4 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ion_trans PF00520.29 001169076.1_40424001_1 - 4.3e-33 114.4 35.6 6e-33 114.0 35.6 1.2 1 0 0 1 1 1 1 Ion transport protein Neur_chan_memb PF02932.14 001169076.1_40424001_1 - 0.001 19.0 0.5 0.003 17.5 0.5 1.7 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PKD_channel PF08016.10 001169076.1_40424001_1 - 0.0065 15.1 25.7 0.012 14.2 15.3 2.3 1 1 1 2 2 2 2 Polycystin cation channel DUF3328 PF11807.6 001169076.1_40424001_1 - 0.21 11.2 0.8 1.6 8.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) SR-25 PF10500.7 001169076.1_40424001_1 - 5.6 6.4 17.9 9.3 5.7 17.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.23 001142889.1_39524001_2 - 8.4e-79 264.5 0.0 1e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001142889.1_39524001_2 - 4.2e-31 108.0 0.0 5.8e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001142889.1_39524001_2 - 1e-07 31.5 0.0 0.00016 21.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.12 001142889.1_39524001_2 - 0.00061 19.1 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001142889.1_39524001_2 - 0.0037 16.8 0.2 0.0072 15.8 0.2 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.21 001142889.1_39524001_2 - 0.0052 16.6 6.6 0.11 12.2 0.3 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family FliG_N PF14842.4 001142889.1_39524001_2 - 0.087 13.2 0.0 0.46 10.9 0.0 2.2 2 1 0 2 2 2 0 FliG N-terminal domain Choline_kinase PF01633.18 001142889.1_39524001_2 - 0.1 12.0 0.8 0.37 10.2 0.8 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Lipocalin PF00061.21 001145180.1_39522001_2 - 2.2e-18 66.7 1.9 2.8e-18 66.4 1.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001145180.1_39522001_2 - 0.0049 16.7 0.6 0.0074 16.1 0.6 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Serpin PF00079.18 001168915.1_40423001_1 - 3.3e-130 434.6 4.9 3.7e-130 434.4 4.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Cu-oxidase_4 PF02578.13 001193989.1_29623001_3 - 2.6e-58 197.1 0.0 4e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase HPS6 PF15702.3 001098590.1_49826001_1 - 2.6e-284 945.0 0.0 3e-284 944.8 0.0 1.0 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 6 protein Chorion_1 PF01723.14 001098590.1_49826001_1 - 0.0075 16.1 0.5 0.059 13.2 0.3 2.2 2 0 0 2 2 2 1 Chorion protein TIP49 PF06068.11 001266990.1_29624001_2 - 8.1e-196 650.5 0.8 9.5e-196 650.3 0.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.10 001266990.1_29624001_2 - 4.5e-14 52.1 1.7 1.3e-08 34.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.27 001266990.1_29624001_2 - 1.9e-12 47.6 0.3 3.5e-08 33.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 001266990.1_29624001_2 - 1.7e-06 28.2 0.1 0.077 13.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.4 001266990.1_29624001_2 - 2.5e-05 24.6 0.0 0.00025 21.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.12 001266990.1_29624001_2 - 8.3e-05 22.5 0.1 0.005 16.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.4 001266990.1_29624001_2 - 0.0002 20.9 0.0 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.24 001266990.1_29624001_2 - 0.00034 20.2 0.1 0.26 10.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.19 001266990.1_29624001_2 - 0.001 18.4 0.2 0.043 13.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.4 001266990.1_29624001_2 - 0.0018 18.5 1.7 0.049 13.8 1.7 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.15 001266990.1_29624001_2 - 0.0019 17.9 0.1 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.4 001266990.1_29624001_2 - 0.0019 18.6 0.0 0.011 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.13 001266990.1_29624001_2 - 0.003 16.8 0.0 0.0066 15.6 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_28 PF13521.4 001266990.1_29624001_2 - 0.0035 17.5 0.1 0.0065 16.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.10 001266990.1_29624001_2 - 0.013 14.7 0.2 0.032 13.4 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.4 001266990.1_29624001_2 - 0.016 15.3 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.14 001266990.1_29624001_2 - 0.016 14.5 0.1 0.043 13.1 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.10 001266990.1_29624001_2 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.13 001266990.1_29624001_2 - 0.018 14.9 0.0 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.15 001266990.1_29624001_2 - 0.019 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.4 001266990.1_29624001_2 - 0.022 14.4 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.15 001266990.1_29624001_2 - 0.025 13.6 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.4 001266990.1_29624001_2 - 0.035 13.7 0.2 0.97 9.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.11 001266990.1_29624001_2 - 0.083 12.1 1.9 0.25 10.5 0.0 2.4 3 0 0 3 3 3 0 KaiC DUF2075 PF09848.7 001266990.1_29624001_2 - 0.091 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.4 001266990.1_29624001_2 - 0.12 12.3 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.20 001266990.1_29624001_2 - 0.15 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase 7tm_1 PF00001.19 001266020.1_29624001_2 - 5.1e-49 166.8 22.2 8.6e-49 166.0 22.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001266020.1_29624001_2 - 1.1e-11 44.4 23.1 1.5e-11 44.1 23.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Glyco_hydro_47 PF01532.18 001284056.1_29524001_1 - 1.4e-113 380.1 0.0 1.8e-113 379.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HGAL PF15666.3 001244130.1_49824001_3 - 1e-36 124.8 3.0 1.7e-36 124.1 3.0 1.3 1 0 0 1 1 1 1 Germinal center-associated lymphoma Ras PF00071.20 001261801.1_29626001_2 - 2.5e-50 170.1 0.0 3.6e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001261801.1_29626001_2 - 1.5e-17 63.8 0.0 2.8e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001261801.1_29626001_2 - 3.6e-08 32.9 0.0 5.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001261801.1_29626001_2 - 0.06 12.8 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Pkinase PF00069.23 001193754.2_29625001_3 - 1.1e-26 93.7 0.1 1.7e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001193754.2_29625001_3 - 6.9e-15 54.9 0.0 1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001193754.2_29625001_3 - 0.086 12.6 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.14 001193754.2_29625001_3 - 0.12 12.5 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 ABC1 family DKCLD PF08068.10 001142513.1_39524001_2 - 2.3e-31 107.5 0.2 1.2e-30 105.3 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.3 001142513.1_39524001_2 - 1.5e-21 76.1 0.6 2.9e-21 75.2 0.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.16 001142513.1_39524001_2 - 2.6e-21 76.4 0.1 2.1e-18 67.0 0.1 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.18 001142513.1_39524001_2 - 3e-18 65.4 1.6 5.8e-18 64.5 1.6 1.5 1 0 0 1 1 1 1 PUA domain Coilin_N PF15862.3 001142513.1_39524001_2 - 0.1 12.3 8.4 0.012 15.3 3.4 2.0 2 0 0 2 2 2 0 Coilin N-terminus FlaC_arch PF05377.9 001126362.1_39522001_1 - 0.12 12.6 0.0 2.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pro_isomerase PF00160.19 001243923.1_49824001_2 - 6e-45 153.2 0.0 1.2e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mito_carr PF00153.25 001195393.1_29622001_1 - 5.8e-67 221.5 3.3 8.1e-25 86.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serpin PF00079.18 001266993.1_29625001_3 - 6e-128 427.1 0.0 7.1e-128 426.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) P2X_receptor PF00864.17 001173107.1_09924001_1 - 6e-155 515.7 1.8 7.2e-155 515.4 1.8 1.0 1 0 0 1 1 1 1 ATP P2X receptor Keratin_matx PF04579.10 001173107.1_09924001_1 - 0.0013 18.9 4.9 0.0013 18.9 4.9 3.4 3 1 0 3 3 3 1 Keratin, high-sulphur matrix protein Y_phosphatase PF00102.25 001244485.1_49826001_2 - 1.1e-167 555.2 8.8 8.9e-85 283.9 0.5 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.18 001244485.1_49826001_2 - 1.6e-09 37.5 0.2 0.001 18.8 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.4 001244485.1_49826001_2 - 9.8e-09 35.4 0.6 0.00043 20.2 0.0 2.8 2 1 1 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.4 001244485.1_49826001_2 - 1.3e-06 28.5 0.4 0.01 15.8 0.1 3.1 3 0 0 3 3 3 2 Inositol hexakisphosphate TMEM154 PF15102.4 001244485.1_49826001_2 - 0.031 14.1 0.1 0.031 14.1 0.1 2.3 2 0 0 2 2 2 0 TMEM154 protein family Rifin_STEVOR PF02009.14 001244485.1_49826001_2 - 0.046 13.5 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Rifin/stevor family Y_phosphatase2 PF03162.11 001244485.1_49826001_2 - 0.33 10.4 2.1 4 6.9 0.0 3.0 3 0 0 3 3 3 0 Tyrosine phosphatase family Adeno_E3_CR2 PF02439.13 001244485.1_49826001_2 - 0.89 9.2 8.0 2.7 7.7 2.6 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Ion_trans PF00520.29 001173062.1_09926001_1 - 3.9e-33 114.5 14.4 6.2e-33 113.9 14.4 1.3 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.9 001173062.1_09926001_1 - 2.6e-28 97.9 0.8 5.3e-28 96.9 0.8 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_4 PF13637.4 001173062.1_09926001_1 - 7.5e-10 39.0 0.0 0.00053 20.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001173062.1_09926001_1 - 8.4e-10 39.0 0.5 3.5e-05 24.2 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.4 001173062.1_09926001_1 - 7.9e-07 28.8 1.6 0.14 12.7 0.1 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.28 001173062.1_09926001_1 - 6.1e-05 23.2 0.3 0.63 10.5 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.4 001173062.1_09926001_1 - 0.00023 21.3 0.0 2.9 8.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.10 001173062.1_09926001_1 - 0.00044 18.9 15.8 0.0075 14.9 15.8 2.3 1 1 0 1 1 1 1 Polycystin cation channel Gp-FAR-1 PF05823.10 001173062.1_09926001_1 - 0.16 12.2 2.6 11 6.2 0.1 2.9 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SPG48 PF14764.4 001244772.1_49826001_3 - 6.8e-42 142.5 1.2 6.8e-42 142.5 1.2 2.4 3 0 0 3 3 3 1 AP-5 complex subunit, vesicle trafficking RRM_1 PF00076.20 001258113.1_29624001_3 - 2.1e-19 69.0 0.0 3.7e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.7 001258113.1_29624001_3 - 0.18 10.5 12.2 0.24 10.1 12.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.15 001258113.1_29624001_3 - 1.8 7.1 7.1 2.5 6.6 7.1 1.1 1 0 0 1 1 1 0 Presenilin adh_short PF00106.23 001195425.1_29623001_3 - 5.3e-53 179.3 4.6 6.9e-53 178.9 4.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001195425.1_29623001_3 - 7.2e-24 84.5 3.1 8.9e-24 84.2 3.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001195425.1_29623001_3 - 1.3e-08 34.8 2.2 2.1e-08 34.2 2.2 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.17 001195425.1_29623001_3 - 0.00082 18.6 0.1 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.8 001195425.1_29623001_3 - 0.0014 17.9 0.1 0.0089 15.3 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Pyr_redox_3 PF13738.4 001195425.1_29623001_3 - 0.015 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.17 001195425.1_29623001_3 - 0.032 13.4 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.18 001195425.1_29623001_3 - 0.034 14.1 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.12 001195425.1_29623001_3 - 0.035 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.13 001195425.1_29623001_3 - 0.035 14.1 0.1 0.062 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase bZIP_2 PF07716.13 001261237.1_29623001_3 - 8.9e-08 32.0 7.8 1.6e-07 31.1 7.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.19 001261237.1_29623001_3 - 0.00076 19.4 6.6 0.00076 19.4 6.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor IL8 PF00048.18 001170516.1_49821001_1 - 2.4e-20 72.3 0.0 2.9e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like CcmD PF04995.12 001170516.1_49821001_1 - 5.3 7.1 8.5 0.65 10.0 3.6 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) PITH PF06201.11 001260794.1_29623001_2 - 1.4e-41 142.1 0.0 1.9e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 PITH domain Pkinase PF00069.23 001261185.1_29623001_3 - 2.7e-74 249.7 0.0 3.3e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001261185.1_29623001_3 - 4.2e-29 101.5 0.0 5.4e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001261185.1_29623001_3 - 2.3e-08 33.6 0.0 1.7e-07 30.7 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001261185.1_29623001_3 - 1e-05 24.9 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001261185.1_29623001_3 - 6.9e-05 22.8 0.1 0.45 10.3 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.20 001261185.1_29623001_3 - 0.0021 17.5 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.4 001261185.1_29623001_3 - 0.0051 16.3 0.0 0.07 12.6 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.18 001261185.1_29623001_3 - 0.042 13.3 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YukC PF10140.7 001261185.1_29623001_3 - 0.087 11.5 0.1 0.15 10.7 0.1 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC TMEM51 PF15345.4 001266081.1_29622001_2 - 0.012 15.4 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 ECSCR PF15820.3 001266081.1_29622001_2 - 0.019 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator OAD_gamma PF04277.11 001266081.1_29622001_2 - 0.039 14.4 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Syndecan PF01034.18 001266081.1_29622001_2 - 0.081 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Syndecan domain SIT PF15330.4 001266081.1_29622001_2 - 0.17 12.1 0.1 0.64 10.3 0.0 1.8 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Mito_carr PF00153.25 001267019.1_29623001_3 - 1.1e-55 185.3 0.8 6.4e-17 61.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein YIF1 PF03878.13 001194498.1_29623001_3 - 5.5e-82 274.7 1.6 6.6e-82 274.5 1.6 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.15 001194498.1_29623001_3 - 5.8e-12 45.5 7.7 1.3e-11 44.4 7.7 1.5 1 0 0 1 1 1 1 Yip1 domain G-gamma PF00631.20 001266194.1_29622001_1 - 7.1e-18 64.3 0.3 1e-17 63.8 0.3 1.2 1 0 0 1 1 1 1 GGL domain HAUS5 PF14817.4 001266194.1_29622001_1 - 0.016 13.7 0.2 0.02 13.4 0.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Copine PF07002.14 001169012.1_40429001_1 - 1.4e-84 282.8 0.0 2.4e-84 282.0 0.0 1.4 1 0 0 1 1 1 1 Copine RRM_1 PF00076.20 001169012.1_40429001_1 - 6.2e-30 102.7 1.0 1.9e-07 30.7 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C2 PF00168.28 001169012.1_40429001_1 - 3.6e-25 88.1 0.0 2.4e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.7 001169012.1_40429001_1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.26 001169012.1_40429001_1 - 0.0065 16.6 0.1 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Guanylate_kin PF00625.19 001257782.1_29629001_3 - 1.4e-49 168.2 0.1 2.2e-49 167.5 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.6 001257782.1_29629001_3 - 7.2e-23 80.3 6.5 2.5e-22 78.6 6.5 2.0 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.26 001257782.1_29629001_3 - 0.0057 16.1 0.1 0.014 14.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain IL8 PF00048.18 001032854.1_29621001_1 - 2.5e-22 78.7 0.4 4e-22 78.0 0.4 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Carb_anhydrase PF00194.19 001284775.1_29524001_3 - 4.8e-90 301.4 0.0 5.8e-90 301.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Neur_chan_LBD PF02931.21 001261668.1_29625001_3 - 2.4e-49 167.6 0.0 3.5e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001261668.1_29625001_3 - 4.6e-38 131.5 6.5 1.5e-30 106.9 5.4 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region MARVEL PF01284.21 001244546.1_49822001_3 - 1.7e-06 28.0 22.0 5.9e-06 26.2 22.0 1.8 1 1 0 1 1 1 1 Membrane-associating domain TMEM237 PF15383.4 001244546.1_49822001_3 - 0.58 9.0 3.3 1.1 8.2 3.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 Chromate_transp PF02417.13 001244546.1_49822001_3 - 0.91 9.5 10.0 1.5 8.9 10.0 1.2 1 0 0 1 1 1 0 Chromate transporter KGG PF10685.7 001244546.1_49822001_3 - 1.3 9.3 4.1 1.2 9.4 0.7 2.2 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif DUF2070 PF09843.7 001244546.1_49822001_3 - 7.2 4.6 13.7 9.2 4.3 13.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_hydro_20 PF00728.20 001261529.1_29624001_3 - 7.9e-84 281.9 0.0 1.2e-83 281.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.4 001261529.1_29624001_3 - 1.1e-23 84.2 0.0 1.7e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.13 001261529.1_29624001_3 - 0.00067 20.3 0.0 0.002 18.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pro_isomerase PF00160.19 001163048.1_39522001_1 - 5.2e-45 153.4 0.0 7.4e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.20 001163048.1_39522001_1 - 3.2e-21 74.8 0.0 5.7e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001163048.1_39522001_1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4944 PF16302.3 001163048.1_39522001_1 - 0.022 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) RRM_occluded PF16842.3 001163048.1_39522001_1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.3 001163048.1_39522001_1 - 0.055 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.4 001163048.1_39522001_1 - 0.17 11.7 0.8 0.6 10.0 0.0 2.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif ETF PF01012.19 001244403.1_49823001_1 - 9.7e-42 142.8 1.4 1.4e-41 142.2 1.4 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.17 001244403.1_49823001_1 - 1.6e-37 127.3 0.4 3.8e-37 126.1 0.4 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Lectin_C PF00059.19 001194668.1_29625001_1 - 4.1e-15 56.3 0.0 4.1e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain Ly49 PF08391.8 001194668.1_29625001_1 - 6e-06 26.5 4.8 1e-05 25.7 4.8 1.4 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region HemX PF04375.12 001194668.1_29625001_1 - 1.6e-05 24.3 5.9 2.3e-05 23.7 5.9 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase IncA PF04156.12 001194668.1_29625001_1 - 6.8e-05 22.6 2.0 0.0001 22.0 2.0 1.3 1 0 0 1 1 1 1 IncA protein UL45 PF05473.10 001194668.1_29625001_1 - 7.6e-05 22.3 0.4 0.0005 19.6 0.1 2.1 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like DUF1664 PF07889.10 001194668.1_29625001_1 - 0.05 13.5 7.3 0.089 12.6 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2570 PF10828.6 001194668.1_29625001_1 - 0.067 12.9 9.5 0.092 12.5 8.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) FAM176 PF14851.4 001194668.1_29625001_1 - 0.074 12.6 0.9 0.13 11.9 0.9 1.3 1 0 0 1 1 1 0 FAM176 family DUF4446 PF14584.4 001194668.1_29625001_1 - 0.11 12.4 2.1 0.18 11.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) MctB PF11382.6 001194668.1_29625001_1 - 0.13 11.8 0.7 0.19 11.3 0.7 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF724 PF05266.12 001194668.1_29625001_1 - 0.68 9.6 9.2 1.2 8.8 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.13 001194668.1_29625001_1 - 0.89 8.9 3.8 1.3 8.4 3.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1690 PF07956.9 001194668.1_29625001_1 - 1.3 9.3 10.5 2.4 8.5 10.5 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) zf-DHHC PF01529.18 001266197.1_29624001_1 - 8.9e-34 116.3 13.1 8.9e-34 116.3 13.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase RRM_1 PF00076.20 001257897.1_29626001_2 - 1.1e-91 300.6 1.7 8.1e-25 86.3 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.16 001257897.1_29626001_2 - 3.4e-32 110.3 0.4 9.8e-32 108.9 0.3 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.4 001257897.1_29626001_2 - 1e-08 34.7 0.1 0.14 11.6 0.1 4.3 1 1 3 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.6 001257897.1_29626001_2 - 1.1e-05 25.3 1.0 3.4 7.7 0.0 4.3 4 0 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.4 001257897.1_29626001_2 - 1.6e-05 24.7 0.1 6.4 6.7 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.6 001257897.1_29626001_2 - 4.6e-05 22.8 0.5 8.4 6.0 0.1 4.4 4 0 0 4 4 4 2 Histone lysine methyltransferase SET associated RRM_7 PF16367.3 001257897.1_29626001_2 - 0.00035 20.5 0.2 12 5.9 0.0 4.7 3 1 1 4 4 4 1 RNA recognition motif RRM_occluded PF16842.3 001257897.1_29626001_2 - 0.0012 18.5 0.0 0.67 9.7 0.0 3.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif ATP-grasp_2 PF08442.8 001257897.1_29626001_2 - 0.01 15.3 0.0 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain RRM_3 PF08777.9 001257897.1_29626001_2 - 0.022 14.7 10.6 0.66 9.9 0.9 3.9 5 0 0 5 5 5 0 RNA binding motif OB_RNB PF08206.9 001257897.1_29626001_2 - 0.071 12.7 3.0 6.6 6.4 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.6 001257897.1_29626001_2 - 0.078 13.4 0.4 3 8.3 0.2 2.6 2 0 0 2 2 2 0 Heat induced stress protein YflT Ank_5 PF13857.4 001146290.1_39723001_3 - 1.4e-10 41.1 2.2 0.0006 20.0 0.5 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.4 001146290.1_39723001_3 - 1e-07 32.2 0.0 0.011 16.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.5 001146290.1_39723001_3 - 1.4e-06 28.7 0.0 0.0087 16.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001146290.1_39723001_3 - 0.0015 18.8 0.1 0.28 11.6 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat bZIP_1 PF00170.19 001169006.1_40422001_1 - 2.6e-10 40.1 7.6 4.2e-10 39.5 7.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001169006.1_40422001_1 - 1.7e-06 27.8 13.7 2.6e-06 27.3 13.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001169006.1_40422001_1 - 2.1e-05 24.8 6.6 3.6e-05 24.1 6.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.16 001169006.1_40422001_1 - 0.0003 20.8 3.8 0.00069 19.6 3.8 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper HAP1_N PF04849.11 001169006.1_40422001_1 - 0.00086 18.5 2.4 0.0012 18.0 2.4 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Vir_act_alpha_C PF10400.7 001169006.1_40422001_1 - 1.8 9.1 5.3 3.3 8.3 5.3 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term APG6 PF04111.10 001169006.1_40422001_1 - 2.4 7.3 7.0 3.4 6.9 7.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HlyIII PF03006.18 001194535.2_29625001_2 - 2.4e-32 112.3 17.0 3.9e-32 111.7 17.0 1.3 1 0 0 1 1 1 1 Haemolysin-III related MFS_1 PF07690.14 001133954.1_43527001_2 - 1.9e-40 138.7 33.7 3e-34 118.4 23.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.8 001133954.1_43527001_2 - 0.54 9.8 5.9 0.23 11.0 0.9 2.3 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) bZIP_1 PF00170.19 001098399.1_29623001_1 - 6.6e-09 35.6 14.0 1e-08 35.0 14.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001098399.1_29623001_1 - 3.6e-06 26.8 14.1 5.7e-06 26.2 14.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001098399.1_29623001_1 - 3.5e-05 24.1 8.9 5.6e-05 23.5 8.9 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.7 001098399.1_29623001_1 - 0.021 13.3 9.0 0.03 12.8 9.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3450 PF11932.6 001098399.1_29623001_1 - 0.14 11.3 2.2 0.2 10.8 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HALZ PF02183.16 001098399.1_29623001_1 - 0.22 11.6 4.4 0.62 10.2 4.2 1.8 1 1 0 1 1 1 0 Homeobox associated leucine zipper EF-1_beta_acid PF10587.7 001098399.1_29623001_1 - 0.52 10.7 4.9 1.2 9.6 4.9 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region APG6 PF04111.10 001098399.1_29623001_1 - 0.54 9.5 4.8 0.77 9.0 4.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.13 001098399.1_29623001_1 - 1.1 8.9 6.1 1.7 8.3 6.1 1.2 1 0 0 1 1 1 0 Mnd1 family GILT PF03227.14 001205150.1_39522001_1 - 1.9e-31 108.3 1.1 2.9e-31 107.7 1.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) zf-RING_4 PF14570.4 001205150.1_39522001_1 - 0.0064 16.1 0.3 3.2 7.4 0.1 2.5 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain ETS_PEA3_N PF04621.11 001132978.1_43529001_3 - 1.9e-134 448.8 18.6 2.7e-134 448.3 18.6 1.2 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.20 001132978.1_43529001_3 - 5e-38 129.3 0.2 8.6e-38 128.6 0.2 1.4 1 0 0 1 1 1 1 Ets-domain RasGEF PF00617.17 001261279.1_29625001_1 - 2e-40 138.7 0.1 4.4e-40 137.5 0.0 1.6 2 0 0 2 2 2 1 RasGEF domain EF-hand_1 PF00036.30 001261279.1_29625001_1 - 2.3e-11 42.3 0.8 1.4e-05 24.1 0.2 2.8 2 0 0 2 2 2 2 EF hand C1_1 PF00130.20 001261279.1_29625001_1 - 2.4e-11 43.2 7.9 4.6e-11 42.3 7.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_6 PF13405.4 001261279.1_29625001_1 - 1.4e-10 40.1 0.2 5.8e-05 22.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.4 001261279.1_29625001_1 - 4.9e-10 39.6 4.8 3.3e-07 30.5 1.1 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001261279.1_29625001_1 - 5.2e-10 38.2 0.7 8.1e-06 25.0 0.2 2.8 2 0 0 2 2 2 2 EF hand RasGEF_N PF00618.18 001261279.1_29625001_1 - 3.2e-09 36.8 0.2 2.6e-07 30.7 0.0 2.9 3 0 0 3 3 3 1 RasGEF N-terminal motif EF-hand_8 PF13833.4 001261279.1_29625001_1 - 6.1e-05 22.6 1.9 0.0034 17.0 0.3 2.5 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001261279.1_29625001_1 - 0.059 13.6 0.1 8.2 6.7 0.0 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region FAA_hydrolase PF01557.16 001257529.2_29623001_2 - 4.9e-57 192.9 0.0 6.9e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.9 001257529.2_29623001_2 - 2.6e-30 104.5 0.0 4.2e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal zf-4CXXC_R1 PF10497.7 001257527.1_29625001_2 - 5.4e-37 125.9 11.4 1e-36 125.0 11.4 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Endonuclease_7 PF02945.13 001257527.1_29625001_2 - 4.2 7.2 14.6 6.9 6.5 8.2 2.4 1 1 1 2 2 2 0 Recombination endonuclease VII WSD PF15613.4 001257527.1_29625001_2 - 7.5 7.0 6.9 76 3.8 6.9 2.3 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif 7tm_1 PF00001.19 001173415.1_09923001_1 - 2.4e-49 167.9 24.6 4.6e-49 166.9 24.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001173415.1_09923001_1 - 2.8e-11 43.2 22.7 3.5e-11 42.8 22.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001173415.1_09923001_1 - 0.0011 18.2 17.7 0.0017 17.6 17.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF423 PF04241.13 001173415.1_09923001_1 - 0.36 10.9 2.6 0.97 9.5 1.1 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF423) MMR_HSR1 PF01926.21 001190917.1_29623001_1 - 5.1e-13 49.0 0.0 1.9e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.14 001190917.1_29623001_1 - 5.8e-07 29.4 0.0 0.025 14.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FeoB_N PF02421.16 001190917.1_29623001_1 - 3.1e-06 26.7 0.1 0.00054 19.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.7 001190917.1_29623001_1 - 0.00062 19.4 0.0 0.47 10.1 0.0 2.6 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.25 001190917.1_29623001_1 - 0.00064 19.2 0.0 0.093 12.1 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.4 001190917.1_29623001_1 - 0.012 15.8 0.0 0.071 13.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.4 001190917.1_29623001_1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain Dynamin_N PF00350.21 001190917.1_29623001_1 - 0.021 14.7 0.2 0.23 11.4 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Roc PF08477.11 001190917.1_29623001_1 - 0.036 14.2 0.0 0.081 13.0 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.11 001190917.1_29623001_1 - 0.046 12.7 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.4 001190917.1_29623001_1 - 0.055 13.9 0.2 0.12 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain MMR_HSR1_Xtn PF16897.3 001190917.1_29623001_1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ras PF00071.20 001190917.1_29623001_1 - 0.11 11.9 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Ras family Septin PF00735.16 001190917.1_29623001_1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Septin Arf PF00025.19 001190917.1_29623001_1 - 0.13 11.6 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family TniB PF05621.9 001190917.1_29623001_1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Ost4 PF10215.7 001265770.1_29621001_1 - 2.2e-16 59.2 1.9 3.2e-16 58.7 1.9 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Renin_r PF07850.12 001283604.1_29525001_1 - 3e-36 123.8 1.3 5e-36 123.1 1.3 1.4 1 0 0 1 1 1 1 Renin receptor-like protein HLH PF00010.24 001177678.1_39523001_3 - 7.7e-10 38.5 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-C3HC4_3 PF13920.4 001265820.1_29624001_3 - 3.4e-11 42.7 11.7 3.4e-11 42.7 11.7 2.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Armet PF10208.7 001265820.1_29624001_3 - 0.00096 19.0 9.8 0.029 14.2 0.2 2.4 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding SAP PF02037.25 001265820.1_29624001_3 - 0.0046 16.6 0.8 1.7 8.3 0.1 2.8 3 0 0 3 3 3 2 SAP domain zf-C3HC4_2 PF13923.4 001265820.1_29624001_3 - 0.0049 16.5 13.3 0.0049 16.5 13.3 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001265820.1_29624001_3 - 0.006 16.3 11.5 0.006 16.3 11.5 2.8 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 HeH PF12949.5 001265820.1_29624001_3 - 0.19 11.4 0.1 12 5.6 0.1 2.3 2 0 0 2 2 2 0 HeH/LEM domain PPP4R2 PF09184.9 001265820.1_29624001_3 - 0.78 9.1 9.7 1.3 8.4 9.7 1.3 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.12 001265820.1_29624001_3 - 1.5 8.4 8.2 3.2 7.4 8.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.9 001265820.1_29624001_3 - 1.7 6.5 6.1 2.4 6.0 6.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cytomega_UL84 PF06284.9 001265820.1_29624001_3 - 3.5 5.9 6.8 5.1 5.3 6.8 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CDC45 PF02724.12 001265820.1_29624001_3 - 4.9 5.2 11.4 6.9 4.7 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.8 001265820.1_29624001_3 - 5 6.2 10.8 6.8 5.8 10.8 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.9 001265820.1_29624001_3 - 6.7 5.0 7.7 9.3 4.5 7.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3504 PF12012.6 001260875.1_29629001_1 - 4.9e-65 218.2 1.2 1.6e-64 216.5 1.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) zf-FCS PF06467.12 001260875.1_29629001_1 - 3.5e-49 164.4 98.5 8.4e-09 35.1 11.6 10.9 10 0 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif DUF504 PF04457.10 001168882.1_40422001_1 - 9.1e-09 35.6 0.0 1.4e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF504) zf-CCCH PF00642.22 001168882.1_40422001_1 - 0.00014 21.6 4.1 0.00027 20.6 4.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.4 001168882.1_40422001_1 - 0.26 11.7 3.1 0.5 10.8 3.1 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C2H2 PF00096.24 001097487.1_49823001_1 - 2.5e-14 52.7 29.3 5.9e-05 23.2 8.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001097487.1_49823001_1 - 5e-09 36.1 14.3 2.1e-05 24.6 0.8 4.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001097487.1_49823001_1 - 1.6e-06 28.3 26.7 0.012 16.3 6.1 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001097487.1_49823001_1 - 0.076 13.2 6.1 0.24 11.6 6.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon DUF3850 PF12961.5 001097487.1_49823001_1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) FOXP-CC PF16159.3 001097487.1_49823001_1 - 1 9.9 7.5 8.1 7.0 2.5 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-met PF12874.5 001097487.1_49823001_1 - 2.7 8.4 12.3 10 6.5 4.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 001097487.1_49823001_1 - 3.6 7.3 8.4 2.3 7.9 2.7 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type DEAD PF00270.27 001258162.1_29628001_3 - 2.1e-46 157.8 0.0 3.9e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase P68HR PF08061.9 001258162.1_29628001_3 - 1.4e-33 114.6 22.6 1.5e-17 63.3 2.4 3.0 3 0 0 3 3 3 2 P68HR (NUC004) repeat Helicase_C PF00271.29 001258162.1_29628001_3 - 1.2e-30 106.0 0.0 2.4e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001258162.1_29628001_3 - 0.0019 18.1 0.0 0.0088 15.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.3 001258162.1_29628001_3 - 0.012 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase adh_short PF00106.23 001194684.1_29623001_3 - 5.2e-39 133.6 0.0 6.8e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001194684.1_29623001_3 - 4.5e-26 91.7 0.0 6.5e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.8 001194684.1_29623001_3 - 0.00087 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.8 001194684.1_29623001_3 - 0.014 15.2 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 KR domain E1-E2_ATPase PF00122.18 001266023.2_29627001_3 - 2.9e-60 203.2 2.8 3.8e-60 202.8 1.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.19 001266023.2_29627001_3 - 8.5e-46 155.8 4.0 8.5e-46 155.8 4.0 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.24 001266023.2_29627001_3 - 2.4e-22 80.2 2.2 9.3e-22 78.2 2.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 001266023.2_29627001_3 - 4.9e-18 64.4 0.0 1.1e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.4 001266023.2_29627001_3 - 5.1e-17 61.6 0.0 5.3e-15 55.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.10 001266023.2_29627001_3 - 0.00022 20.9 2.7 0.00055 19.6 2.7 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GYF PF02213.14 001283430.1_29524001_2 - 2.5e-18 65.4 1.3 6.2e-18 64.1 1.3 1.7 1 0 0 1 1 1 1 GYF domain Pkinase PF00069.23 001260761.1_29626001_1 - 2.8e-35 121.8 0.0 4.2e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001260761.1_29626001_1 - 3.5e-35 121.4 0.0 5.1e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.10 001260761.1_29626001_1 - 3.5e-17 61.4 0.4 6.8e-17 60.5 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif APH PF01636.21 001260761.1_29626001_1 - 0.015 15.1 0.1 0.062 13.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.4 001260761.1_29626001_1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.23 001266657.1_29623001_1 - 9.5e-75 251.2 0.0 1.1e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001266657.1_29623001_1 - 3.1e-32 111.8 0.0 3.9e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001266657.1_29623001_1 - 2e-06 27.2 0.1 0.0021 17.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.9 001266657.1_29623001_1 - 0.00017 20.6 0.0 0.0021 17.0 0.0 2.0 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.21 001266657.1_29623001_1 - 0.0078 16.0 0.5 0.015 15.1 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.20 001266657.1_29623001_1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.4 001266657.1_29623001_1 - 0.072 12.6 0.1 0.62 9.5 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EMG1 PF03587.12 001243478.1_49822001_3 - 7.8e-84 280.0 0.0 9.4e-84 279.8 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase HA2 PF04408.21 001257881.1_29629001_1 - 1.1e-19 70.5 0.0 1.1e-19 70.5 0.0 4.4 5 1 0 5 5 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.14 001257881.1_29629001_1 - 4e-19 68.7 0.0 1.4e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.29 001257881.1_29629001_1 - 1.3e-13 51.2 0.0 2.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.27 001257881.1_29629001_1 - 2.2e-07 30.7 0.0 5.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.4 001257881.1_29629001_1 - 1.6e-05 25.1 0.0 4.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.4 001257881.1_29629001_1 - 0.00056 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.4 001257881.1_29629001_1 - 0.0023 18.2 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.18 001257881.1_29629001_1 - 0.0035 16.3 0.0 0.0065 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.14 001257881.1_29629001_1 - 0.021 14.2 0.1 0.044 13.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.12 001257881.1_29629001_1 - 0.043 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain NB-ARC PF00931.20 001257881.1_29629001_1 - 0.043 12.7 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.4 001257881.1_29629001_1 - 0.14 12.2 0.0 0.14 12.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain RTC PF01137.19 001257757.1_29624001_1 - 6.5e-61 205.2 0.0 8e-61 204.9 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.11 001257757.1_29624001_1 - 9.8e-37 125.5 0.4 1e-35 122.2 0.0 2.2 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain 2TM PF13239.4 001257757.1_29624001_3 - 0.92 9.7 4.9 1.7 8.8 4.9 1.4 1 0 0 1 1 1 0 2TM domain 7tm_1 PF00001.19 001001623.1_49824001_1 - 8.1e-41 139.9 30.3 2.3e-40 138.4 30.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001623.1_49824001_1 - 0.00043 19.6 24.8 0.00057 19.2 24.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Guanylate_kin PF00625.19 001260678.2_29624001_1 - 8.9e-51 172.0 0.1 1.7e-50 171.1 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.14 001260678.2_29624001_1 - 9.6e-29 98.8 2.0 5.4e-17 61.2 0.1 3.1 3 0 0 3 3 3 2 L27 domain SH3_2 PF07653.15 001260678.2_29624001_1 - 1e-11 44.2 0.2 3.3e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PDZ PF00595.22 001260678.2_29624001_1 - 9.9e-11 41.7 0.9 2e-10 40.7 0.9 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_1 PF00018.26 001260678.2_29624001_1 - 5.1e-06 25.8 0.1 1.1e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 001260678.2_29624001_1 - 4.4e-05 23.1 0.0 8.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.4 001260678.2_29624001_1 - 0.00015 21.9 0.1 0.00037 20.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.4 001260678.2_29624001_1 - 0.00074 19.3 0.1 0.013 15.4 0.2 2.7 2 1 0 2 2 2 1 Tricorn protease PDZ domain IRK PF01007.18 001172710.1_09925001_3 - 9.8e-152 504.5 0.0 1.3e-151 504.1 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.14 001172710.1_09925001_3 - 0.0035 17.1 0.2 0.0035 17.1 0.2 2.2 2 0 0 2 2 2 1 Ion channel IRK_N PF08466.8 001172710.1_09925001_3 - 2.5 8.2 6.5 0.29 11.2 1.8 1.8 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal Retrotrans_gag PF03732.15 001314207.1_09023001_1 - 0.00047 20.3 0.8 0.0016 18.5 0.8 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein DUF842 PF05811.11 001314207.1_09023001_1 - 0.016 14.9 0.1 0.044 13.5 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF3583 PF12126.6 001314207.1_09023001_1 - 0.076 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF4635 PF15466.4 001314207.1_09023001_1 - 0.21 11.0 2.3 6.4 6.2 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) Mab-21 PF03281.12 001194220.1_29627001_3 - 4.6e-98 328.1 0.0 6.2e-98 327.6 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein Ion_trans PF00520.29 001168921.1_40427001_1 - 1.5e-10 40.6 20.5 3.4e-10 39.4 20.0 1.9 1 1 0 1 1 1 1 Ion transport protein IL8 PF00048.18 001032936.1_29621001_1 - 3.9e-16 58.8 0.3 3.9e-16 58.8 0.3 1.6 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like Rtf2 PF04641.10 001032936.1_29621001_1 - 0.17 11.1 11.4 0.27 10.4 11.4 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger O-antigen_lig PF13425.4 001032936.1_29621001_1 - 0.18 10.4 0.3 0.19 10.3 0.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Ank_5 PF13857.4 001261281.1_29629001_1 - 5.7e-105 341.4 44.1 2.2e-12 46.8 0.4 14.7 5 5 9 14 14 14 14 Ankyrin repeats (many copies) Ank PF00023.28 001261281.1_29629001_1 - 3.8e-104 336.9 52.1 1.5e-07 31.4 0.1 18.3 18 0 0 18 18 18 16 Ankyrin repeat Ank_2 PF12796.5 001261281.1_29629001_1 - 1.1e-102 336.6 46.7 3.5e-15 56.2 0.2 11.0 4 4 6 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001261281.1_29629001_1 - 1.7e-98 321.7 26.7 6.8e-13 48.7 0.2 13.7 8 3 7 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.4 001261281.1_29629001_1 - 1.2e-88 280.1 33.0 1.8e-06 27.7 0.1 18.4 19 0 0 19 19 19 16 Ankyrin repeat PARP PF00644.18 001261281.1_29629001_1 - 8.5e-27 94.0 3.7 8.3e-25 87.5 3.7 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.15 001261281.1_29629001_1 - 2.8e-14 52.8 0.4 5.7e-14 51.8 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001261281.1_29629001_1 - 5.3e-12 45.9 0.6 1.1e-11 44.9 0.6 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-DHHC PF01529.18 001261639.2_29623001_2 - 1.8e-32 112.1 12.7 1.8e-32 112.1 12.7 3.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF1658 PF07871.9 001261639.2_29623001_2 - 0.014 15.1 0.1 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) Serpin PF00079.18 001174114.2_39523001_1 - 9.5e-107 357.4 0.2 9.5e-107 357.4 0.2 1.3 2 0 0 2 2 2 1 Serpin (serine protease inhibitor) F-actin_cap_A PF01267.15 001168609.1_29625001_2 - 8.2e-106 353.2 1.2 1.1e-105 352.8 1.2 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Glyco_transf_64 PF09258.8 001267005.1_29626001_2 - 1.2e-84 283.3 0.0 1.7e-84 282.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.4 001267005.1_29626001_2 - 0.016 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF1049 PF06305.9 001267005.1_29626001_2 - 0.045 13.5 0.9 0.11 12.2 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) ATP-synt_S1 PF05827.10 001168804.1_40423001_1 - 6.4e-54 181.6 0.9 9.2e-54 181.1 0.9 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.15 001168804.1_40423001_1 - 0.042 13.3 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) 7tm_1 PF00001.19 001172755.1_09925001_3 - 1.2e-67 227.8 9.8 1.7e-67 227.4 9.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001172755.1_09925001_3 - 0.00024 20.4 4.7 0.00047 19.5 4.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001172755.1_09925001_3 - 0.00073 18.8 0.8 0.0014 17.9 0.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.7 001172755.1_09925001_3 - 0.0034 16.6 0.4 0.0096 15.2 0.3 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TctB PF07331.9 001172755.1_09925001_3 - 1.4 9.1 9.4 2.7 8.1 1.4 2.8 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Cep57_CLD PF14073.4 001193486.1_29623001_1 - 3.2e-63 212.8 37.8 3.2e-63 212.8 37.8 2.5 2 0 0 2 2 2 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.11 001193486.1_29623001_1 - 3.9e-19 68.8 7.8 3.9e-19 68.8 7.8 4.5 2 1 1 4 4 4 2 Centrosome microtubule-binding domain of Cep57 Vac_Fusion PF02346.14 001193486.1_29623001_1 - 2.3 7.8 9.9 2 8.0 0.1 3.5 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 RSRP PF17069.3 001243642.1_49823001_1 - 2e-92 309.9 72.2 2.4e-92 309.6 72.2 1.1 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 Serpin PF00079.18 001308593.1_39524001_2 - 1.2e-93 314.3 0.0 1.3e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) CIDE-N PF02017.13 001306115.1_39523001_1 - 2.5e-27 94.6 0.0 3.9e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 CIDE-N domain Peptidase_C54 PF03416.17 001190284.1_49826001_2 - 5.5e-102 340.6 0.0 7.3e-102 340.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Y_phosphatase PF00102.25 001169015.1_40426001_1 - 3.4e-73 246.0 0.0 4.6e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RESP18 PF14948.4 001169015.1_40426001_1 - 7.4e-34 116.1 0.7 7.4e-34 116.1 0.7 2.2 2 0 0 2 2 2 1 RESP18 domain Receptor_IA-2 PF11548.6 001169015.1_40426001_1 - 5.8e-33 112.6 0.0 1.1e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase receptor IA-2 DSPc PF00782.18 001169015.1_40426001_1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Porin_3 PF01459.20 001260795.1_29624001_3 - 6.6e-77 258.5 0.2 8.3e-77 258.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic porin IL8 PF00048.18 001166491.1_49822001_3 - 2.1e-13 50.0 4.0 3.1e-13 49.5 4.0 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like U1snRNP70_N PF12220.6 001194832.2_29624001_2 - 7.6e-28 96.9 6.3 7.6e-28 96.9 6.3 4.4 3 1 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.20 001194832.2_29624001_2 - 4.8e-18 64.6 0.0 8.2e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001194832.2_29624001_2 - 0.16 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.7 001194832.2_29624001_2 - 8.2 4.9 52.0 0.14 10.8 42.7 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Aa_trans PF01490.16 001266377.1_29626001_2 - 2.1e-98 329.6 20.2 2.6e-98 329.3 20.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PhzC-PhzF PF02567.14 001193774.1_29623001_1 - 9.8e-60 202.3 0.0 1.2e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Serpin PF00079.18 001193923.2_29624001_1 - 3.6e-132 441.0 4.5 4.1e-132 440.8 4.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) LRR_4 PF12799.5 001266042.1_29625001_2 - 3.1e-13 49.5 7.2 3.8e-08 33.3 2.5 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001266042.1_29625001_2 - 3.9e-07 29.6 6.6 9.3e-07 28.4 1.6 2.7 1 1 1 2 2 2 2 Leucine rich repeat WD40 PF00400.30 001266042.1_29625001_2 - 0.005 17.5 5.5 0.024 15.4 0.1 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat LRR_9 PF14580.4 001266042.1_29625001_2 - 0.14 11.5 0.6 0.24 10.7 0.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.4 001266042.1_29625001_2 - 0.25 11.4 4.7 6.7 6.9 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.31 001266042.1_29625001_2 - 0.38 11.3 12.8 1.1 9.8 1.8 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat Lamp PF01299.15 001244255.1_49826001_1 - 5.8e-117 390.6 12.1 7.4e-115 383.7 6.9 2.1 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.10 001244255.1_49826001_1 - 2.8e-11 43.3 2.4 9.2e-09 35.1 0.2 2.4 2 0 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) OCRL_clath_bd PF16726.3 001265789.1_29629001_1 - 1.2e-43 147.4 0.5 4.2e-43 145.6 0.4 1.9 2 0 0 2 2 2 1 Inositol polyphosphate 5-phosphatase clathrin binding domain RhoGAP PF00620.25 001265789.1_29629001_1 - 1e-25 90.2 0.2 1.6e-25 89.5 0.2 1.3 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.21 001265789.1_29629001_1 - 9.8e-09 35.3 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family INPP5B_PH PF16776.3 001265789.1_29629001_1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain bZIP_Maf PF03131.15 001194569.2_29625001_3 - 1.4e-32 111.9 11.8 2.4e-32 111.2 11.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.13 001194569.2_29625001_3 - 0.00055 19.5 5.9 0.00055 19.5 5.9 2.2 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.19 001194569.2_29625001_3 - 0.0011 18.9 15.1 0.0043 17.0 15.1 2.0 1 1 0 1 1 1 1 bZIP transcription factor Prominin PF05478.9 001194569.2_29625001_3 - 0.009 13.9 1.4 0.013 13.4 1.4 1.1 1 0 0 1 1 1 1 Prominin VIT1 PF01988.17 001194569.2_29625001_3 - 0.0092 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 VIT family DUF1192 PF06698.9 001194569.2_29625001_3 - 0.028 14.3 5.6 0.2 11.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ThrE_2 PF12821.5 001194569.2_29625001_3 - 0.042 13.9 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE Cnn_1N PF07989.9 001194569.2_29625001_3 - 0.057 13.4 7.7 0.11 12.5 7.7 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.3 001194569.2_29625001_3 - 0.18 11.8 1.7 0.32 10.9 1.7 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.13 001194569.2_29625001_3 - 0.18 11.8 12.6 0.34 10.9 11.6 2.1 1 1 0 1 1 1 0 Basic region leucine zipper DUF342 PF03961.11 001194569.2_29625001_3 - 0.24 9.8 3.5 0.33 9.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.10 001194569.2_29625001_3 - 0.34 10.1 5.1 0.49 9.6 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Bap31 PF05529.10 001194569.2_29625001_3 - 1.3 8.5 6.1 2.4 7.6 6.1 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like JIP_LZII PF16471.3 001194569.2_29625001_3 - 1.4 9.0 7.0 0.23 11.5 2.6 1.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DASH_Spc19 PF08287.9 001194569.2_29625001_3 - 1.7 8.4 11.2 2.8 7.7 11.2 1.2 1 0 0 1 1 1 0 Spc19 IncA PF04156.12 001194569.2_29625001_3 - 1.8 8.1 9.1 1.1 8.9 6.3 1.6 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.11 001194569.2_29625001_3 - 2.5 8.6 6.9 1 9.9 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mst1_SARAH PF11629.6 001194569.2_29625001_3 - 9.1 6.3 7.5 19 5.3 1.7 2.7 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 PRKCSH PF07915.11 001132097.1_43526001_3 - 1.3e-15 58.0 5.1 1.3e-15 58.0 5.1 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.4 001132097.1_43526001_3 - 0.00046 19.8 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DNA_pol_phi PF04931.11 001132097.1_43526001_3 - 0.075 11.0 18.3 0.13 10.2 18.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi ATG27 PF09451.8 001132097.1_43526001_3 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 Nucleo_P87 PF07267.9 001132097.1_43526001_3 - 1.1 7.9 7.9 1.9 7.1 7.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Astro_capsid_p PF12226.6 001132097.1_43526001_3 - 1.9 7.4 7.3 3.3 6.6 7.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Y_phosphatase PF00102.25 001278382.1_29629001_3 - 1.3e-144 479.7 4.3 2.1e-85 285.9 0.8 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Carb_anhydrase PF00194.19 001278382.1_29629001_3 - 9.3e-72 241.5 0.2 1.6e-71 240.7 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase fn3 PF00041.19 001278382.1_29629001_3 - 1.5e-12 47.6 0.0 4.8e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain DSPc PF00782.18 001278382.1_29629001_3 - 0.00074 19.2 0.2 0.027 14.2 0.0 2.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.4 001278382.1_29629001_3 - 0.0061 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Peptidase_C10 PF01640.15 001278382.1_29629001_3 - 0.039 14.1 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Peptidase C10 family DUF912 PF06024.10 001278382.1_29629001_3 - 0.076 13.2 0.0 0.35 11.1 0.0 2.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NOA36 PF06524.10 001278382.1_29629001_3 - 2.2 7.5 6.6 4.1 6.6 6.6 1.3 1 0 0 1 1 1 0 NOA36 protein zf-U11-48K PF05253.10 001266192.1_29623001_2 - 7.7e-09 35.1 1.1 1.6e-08 34.1 1.1 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger PMBR PF09373.8 001266192.1_29623001_2 - 0.049 13.7 0.6 10 6.3 0.1 3.2 3 0 0 3 3 3 0 Pseudomurein-binding repeat Presenilin PF01080.15 001266192.1_29623001_2 - 1.1 7.8 6.3 1.5 7.3 6.3 1.2 1 0 0 1 1 1 0 Presenilin Guanylate_kin PF00625.19 001261546.1_29624001_3 - 1.9e-65 219.8 0.2 3.1e-65 219.1 0.2 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.22 001261546.1_29624001_3 - 5.3e-20 71.4 1.3 1.3e-19 70.1 1.3 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.15 001261546.1_29624001_3 - 4.3e-10 39.0 0.0 9.6e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001261546.1_29624001_3 - 1.7e-08 33.8 0.8 8.6e-08 31.5 0.8 2.3 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.4 001261546.1_29624001_3 - 5.7e-05 23.2 0.3 0.00021 21.4 0.0 2.0 2 0 0 2 2 2 1 PDZ domain SH3_9 PF14604.4 001261546.1_29624001_3 - 0.00028 20.5 0.0 0.00059 19.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF258 PF03193.14 001261546.1_29624001_3 - 0.0023 17.7 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001261546.1_29624001_3 - 0.03 14.3 0.0 0.074 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase P33MONOX PF15302.4 001261546.1_29624001_3 - 0.052 13.1 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 P33 mono-oxygenase AAA_22 PF13401.4 001261546.1_29624001_3 - 0.1 12.7 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Carb_anhydrase PF00194.19 001257824.1_29626001_1 - 2.8e-90 302.2 0.1 3.6e-90 301.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase IRK PF01007.18 001173123.1_09925001_2 - 1.6e-138 461.0 3.7 2e-138 460.7 3.7 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel 7tm_1 PF00001.19 001198703.1_29624001_3 - 1.9e-40 138.6 18.1 3.3e-40 137.9 18.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.7 001198703.1_29624001_3 - 0.016 14.4 0.7 0.072 12.2 0.7 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw APC_basic PF05956.9 001206431.1_49829001_2 - 9.7e-115 383.5 45.4 9.7e-115 383.5 45.4 4.5 6 0 0 6 6 3 1 APC basic domain APC_N_CC PF16689.3 001206431.1_49829001_2 - 6.5e-30 102.8 3.4 1.8e-29 101.4 3.4 1.8 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain Suppressor_APC PF11414.6 001206431.1_49829001_2 - 2.1e-25 88.4 5.2 7e-25 86.8 5.2 2.0 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein Arm_APC_u3 PF16629.3 001206431.1_49829001_2 - 1.6e-23 83.6 0.0 4.5e-23 82.1 0.0 1.7 1 1 0 1 1 1 1 Armadillo-associated region on APC Arm PF00514.21 001206431.1_49829001_2 - 3.1e-20 71.4 11.5 8.1e-08 31.9 0.2 6.9 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat APC_r PF05923.10 001206431.1_49829001_2 - 7e-20 70.1 41.0 3.3e-06 26.5 0.2 5.8 5 0 0 5 5 5 5 APC repeat SAMP PF05924.9 001206431.1_49829001_2 - 1.1e-15 56.2 1.1 2.3e-07 29.7 0.5 2.9 2 0 0 2 2 2 2 SAMP Motif ZapB PF06005.10 001206431.1_49829001_2 - 0.014 15.7 5.9 0.08 13.3 5.9 2.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.19 001206431.1_49829001_2 - 0.027 14.4 0.8 0.088 12.8 0.8 1.9 1 0 0 1 1 1 0 bZIP transcription factor HMMR_C PF15908.3 001206431.1_49829001_2 - 0.096 12.8 0.7 0.22 11.6 0.7 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal HALZ PF02183.16 001206431.1_49829001_2 - 0.16 12.1 1.8 0.35 11.0 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Herpes_BLRF2 PF05812.10 001206431.1_49829001_2 - 0.16 11.9 1.4 0.92 9.5 1.4 2.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein JIP_LZII PF16471.3 001206431.1_49829001_2 - 1.3 9.1 5.9 0.37 10.9 0.7 2.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II JAKMIP_CC3 PF16034.3 001206431.1_49829001_2 - 1.6 8.5 11.0 0.53 10.1 7.4 2.0 2 0 0 2 2 2 0 JAKMIP CC3 domain Sec2p PF06428.9 001206431.1_49829001_2 - 1.9 8.4 6.8 0.45 10.4 2.8 2.1 2 0 0 2 2 1 0 GDP/GTP exchange factor Sec2p Wtap PF17098.3 001206431.1_49829001_2 - 2.7 7.8 11.7 0.35 10.7 6.3 2.3 3 0 0 3 3 2 0 WTAP/Mum2p family fn3 PF00041.19 001173053.1_09926001_2 - 1.7e-10 41.0 4.7 0.0085 16.3 0.2 4.1 4 0 0 4 4 4 3 Fibronectin type III domain IL6Ra-bind PF09240.8 001173053.1_09926001_2 - 3.7e-10 39.9 5.7 1.4e-08 34.9 0.3 2.3 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding IL4Ra_N PF09238.8 001173053.1_09926001_2 - 5.2e-09 36.2 3.2 0.00053 20.1 0.1 2.4 2 0 0 2 2 2 2 Interleukin-4 receptor alpha chain, N-terminal EpoR_lig-bind PF09067.8 001173053.1_09926001_2 - 1.1e-06 28.7 0.3 6.9e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding Tissue_fac PF01108.15 001173053.1_09926001_2 - 3.8e-05 23.3 2.9 0.01 15.5 0.0 3.6 2 1 1 3 3 3 1 Tissue factor Pur_ac_phosph_N PF16656.3 001173053.1_09926001_2 - 0.0022 18.4 1.1 0.066 13.7 0.7 2.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Pet127 PF08634.8 001173053.1_09926001_2 - 0.22 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet127 Endosulfine PF04667.15 001266449.1_29628001_1 - 7.4e-09 35.5 1.4 1.2e-08 34.8 1.4 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Lebercilin PF15619.4 001266344.1_29629001_3 - 1.1e-62 211.0 43.2 1.1e-62 211.0 43.2 2.3 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease RRM_1 PF00076.20 001261232.2_29624001_2 - 2.6e-39 132.7 0.0 9.4e-20 70.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001261232.2_29624001_2 - 1.4e-06 28.1 0.0 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.4 001261232.2_29624001_2 - 0.0013 18.2 0.0 0.54 9.7 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.9 001261232.2_29624001_2 - 0.021 14.4 0.1 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.6 001261232.2_29624001_2 - 0.12 12.4 0.0 4.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Ank_4 PF13637.4 001283613.1_29526001_3 - 1.9e-05 24.9 0.0 0.88 10.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.4 001283613.1_29526001_3 - 3.4e-05 23.9 0.5 0.02 15.1 0.5 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001283613.1_29526001_3 - 0.00015 22.1 0.0 0.00058 20.3 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001283613.1_29526001_3 - 0.046 14.1 0.1 0.6 10.5 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat TGF_beta PF00019.18 001169019.1_40423001_1 - 6.5e-14 52.5 0.3 2.9e-13 50.5 0.3 1.9 1 1 0 1 1 1 1 Transforming growth factor beta like domain RRM_1 PF00076.20 001285631.1_09025001_2 - 6.4e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tox-ODYAM1 PF15642.4 001285631.1_09025001_2 - 0.43 9.4 1.7 0.68 8.7 1.7 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Glyco_transf_7N PF13733.4 001257591.1_29629001_1 - 1.5e-52 176.7 0.0 2.3e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.12 001257591.1_29629001_1 - 3.7e-27 93.7 0.7 6.5e-27 92.9 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Peptidase_C2 PF00648.19 001127267.1_39525001_1 - 6.5e-128 425.8 0.0 1.1e-127 425.0 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.20 001127267.1_39525001_1 - 4.3e-53 179.3 0.0 1.4e-52 177.6 0.0 1.9 2 0 0 2 2 2 1 Calpain large subunit, domain III EF-hand_8 PF13833.4 001127267.1_39525001_1 - 7.7e-14 51.1 7.8 1.1e-10 41.0 0.1 4.1 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.4 001127267.1_39525001_1 - 3e-10 39.1 6.1 0.0061 16.3 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.30 001127267.1_39525001_1 - 4.3e-10 38.3 5.7 0.01 15.2 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.4 001127267.1_39525001_1 - 5.4e-08 33.1 5.9 0.028 14.7 1.4 4.1 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.4 001127267.1_39525001_1 - 0.1 12.0 7.9 2.1 7.9 0.0 4.4 4 0 0 4 4 4 0 EF hand Pkinase PF00069.23 001261235.1_29626001_2 - 1.3e-26 93.5 0.0 1.7e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001261235.1_29626001_2 - 1.2e-13 50.8 0.0 1.5e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ADIP PF11559.6 001257628.1_29628001_1 - 0.005 16.8 14.3 0.005 16.8 14.3 5.1 3 1 2 5 5 5 1 Afadin- and alpha -actinin-Binding PolyA_pol PF01743.18 001257628.1_29628001_1 - 1.5 9.1 3.5 5.9 7.2 0.3 2.5 2 0 0 2 2 2 0 Poly A polymerase head domain Reo_sigmaC PF04582.10 001257628.1_29628001_1 - 1.6 7.9 11.9 1.2 8.4 4.8 2.5 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Atg8 PF02991.14 001285597.1_09021001_1 - 6.7e-50 167.5 0.1 7.9e-50 167.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.11 001285597.1_09021001_1 - 7.1e-06 26.2 0.0 8.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Ras PF00071.20 001266422.2_29624001_1 - 1.1e-26 93.2 0.5 1.7e-26 92.7 0.5 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001266422.2_29624001_1 - 8.3e-11 42.0 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001266422.2_29624001_1 - 4.9e-09 35.8 0.4 6.8e-09 35.3 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001266422.2_29624001_1 - 0.00097 18.6 0.7 0.8 9.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001266422.2_29624001_1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.17 001266422.2_29624001_1 - 0.071 12.6 3.7 0.81 9.1 0.5 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HD PF01966.20 001287721.1_29524001_1 - 5.2e-18 65.3 0.0 1.7e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 HD domain SAM_1 PF00536.28 001287721.1_29524001_1 - 2.3e-09 37.4 0.0 5.6e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 001287721.1_29524001_1 - 4.1e-09 36.3 0.0 9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001287721.1_29524001_1 - 0.0084 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ste50p-SAM PF09235.8 001287721.1_29524001_1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif zf-C4 PF00105.16 001306125.1_39524001_3 - 1e-31 109.1 15.5 1e-31 109.1 15.5 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001306125.1_39524001_3 - 8.1e-22 77.7 0.0 1.5e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor vATP-synt_E PF01991.16 001194583.1_29623001_3 - 1.9e-68 229.7 12.5 2.3e-68 229.4 12.5 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Av_adeno_fibre PF06536.9 001194583.1_29623001_3 - 0.086 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Avian adenovirus fibre, N-terminal DUF4288 PF14119.4 001194583.1_29623001_3 - 0.27 11.6 5.2 0.14 12.5 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) RRM_1 PF00076.20 001130937.1_39522001_1 - 8e-20 70.3 0.0 1.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.7 001130937.1_39522001_1 - 0.064 12.0 13.2 0.08 11.7 13.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.7 001130937.1_39522001_1 - 0.59 8.5 6.7 0.62 8.4 6.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Presenilin PF01080.15 001130937.1_39522001_1 - 2.1 6.9 6.9 2.5 6.6 6.9 1.1 1 0 0 1 1 1 0 Presenilin SOBP PF15279.4 001130937.1_39522001_1 - 3.1 8.2 12.2 5 7.5 12.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Rhodanese PF00581.18 001132973.1_43528001_1 - 1.1e-10 41.8 0.0 2.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Filament PF00038.19 001260545.1_29624001_3 - 1.6e-116 389.2 42.8 1.8e-116 388.9 42.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.3 001260545.1_29624001_3 - 2.2e-15 57.1 15.4 3.1e-15 56.6 2.4 2.4 2 0 0 2 2 2 1 Keratin type II head TPR_MLP1_2 PF07926.10 001260545.1_29624001_3 - 8.6e-05 22.5 3.6 8.6e-05 22.5 3.6 4.0 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.9 001260545.1_29624001_3 - 0.00066 18.5 38.7 0.071 11.8 13.0 3.2 1 1 1 2 2 2 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.7 001260545.1_29624001_3 - 0.0009 19.1 38.9 0.026 14.4 8.6 3.8 1 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.6 001260545.1_29624001_3 - 0.0012 18.9 28.3 0.011 15.7 6.4 3.9 2 2 0 3 3 3 2 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.9 001260545.1_29624001_3 - 0.0012 17.4 34.1 0.0076 14.8 19.1 2.1 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.12 001260545.1_29624001_3 - 0.0064 16.2 35.3 0.1 12.3 7.1 3.3 1 1 1 2 2 1 1 IncA protein TraC PF07820.10 001260545.1_29624001_3 - 0.015 15.4 5.0 0.19 11.9 2.4 2.9 2 0 0 2 2 2 0 TraC-like protein TolA_bind_tri PF16331.3 001260545.1_29624001_3 - 0.022 14.7 1.1 0.022 14.7 1.1 5.5 5 2 1 6 6 6 0 TolA binding protein trimerisation DivIC PF04977.13 001260545.1_29624001_3 - 0.024 14.3 1.0 0.024 14.3 1.0 5.9 3 2 4 7 7 7 0 Septum formation initiator HTH_Tnp_Tc3_1 PF11427.6 001260545.1_29624001_3 - 0.13 12.0 0.5 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Tc3 transposase Taxilin PF09728.7 001260545.1_29624001_3 - 0.13 11.4 33.0 0.51 9.4 33.1 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein ABC_tran_CTD PF16326.3 001260545.1_29624001_3 - 0.53 10.4 33.7 0.048 13.8 7.4 4.4 3 2 1 4 4 4 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.7 001260545.1_29624001_3 - 0.61 10.2 34.2 0.79 9.8 8.4 3.5 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 GAS PF13851.4 001260545.1_29624001_3 - 1.4 8.1 38.0 0.04 13.1 5.0 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.10 001260545.1_29624001_3 - 1.5 8.7 22.2 0.22 11.4 1.0 4.7 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) ATG16 PF08614.9 001260545.1_29624001_3 - 1.5 8.8 33.3 11 6.0 10.7 4.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cnn_1N PF07989.9 001260545.1_29624001_3 - 2.8 8.0 22.2 0.045 13.7 2.5 4.2 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 COMP PF11598.6 001260545.1_29624001_3 - 2.9 8.3 6.7 3.5 8.1 0.9 3.1 3 0 0 3 3 2 0 Cartilage oligomeric matrix protein DUF1451 PF07295.9 001260545.1_29624001_3 - 4 7.4 16.4 2.6 8.0 2.0 2.8 2 1 0 2 2 2 0 Zinc-ribbon containing domain E2R135 PF11570.6 001260545.1_29624001_3 - 4.1 7.6 7.9 0.49 10.6 1.8 2.5 2 1 1 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF5082 PF16888.3 001260545.1_29624001_3 - 5.7 7.2 31.8 0.085 13.1 4.4 4.4 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF4407 PF14362.4 001260545.1_29624001_3 - 6.8 5.8 24.5 6.2 5.9 15.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BRE1 PF08647.9 001260545.1_29624001_3 - 8.7 6.4 36.7 0.053 13.5 5.8 4.7 1 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase Elf-1_N PF12310.6 001260954.2_29627001_2 - 5e-45 152.5 3.5 1.3e-44 151.1 3.5 1.8 1 0 0 1 1 1 1 Transcription factor protein N terminal Ets PF00178.20 001260954.2_29627001_2 - 3.4e-34 117.0 1.0 5.8e-34 116.3 1.0 1.4 1 0 0 1 1 1 1 Ets-domain PAPA-1 PF04795.10 001260954.2_29627001_2 - 2.8 8.7 5.7 0.78 10.4 0.8 2.4 2 1 0 2 2 2 0 PAPA-1-like conserved region zf-C2H2 PF00096.24 001198728.1_29627001_1 - 5.3e-13 48.5 36.8 3.5e-05 23.9 4.9 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001198728.1_29627001_1 - 8.1e-11 41.7 39.1 0.0041 17.7 1.6 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001198728.1_29627001_1 - 1.9e-05 24.4 24.0 0.0011 18.7 1.7 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001198728.1_29627001_1 - 3.2e-05 24.0 19.6 0.03 14.5 1.2 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.4 001198728.1_29627001_1 - 0.00015 21.9 20.5 0.58 10.6 0.2 6.7 6 0 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.5 001198728.1_29627001_1 - 0.0021 18.2 21.4 0.026 14.8 0.3 4.9 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-Di19 PF05605.10 001198728.1_29627001_1 - 0.014 15.5 22.7 0.078 13.1 0.2 4.9 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.4 001198728.1_29627001_1 - 0.016 15.1 0.4 3.2 7.7 0.0 3.1 3 0 0 3 3 3 0 CpXC protein zf-BED PF02892.13 001198728.1_29627001_1 - 0.59 10.1 14.2 0.41 10.6 0.2 3.7 4 0 0 4 4 4 0 BED zinc finger Pkinase PF00069.23 001266890.1_29628001_2 - 3.1e-25 88.9 0.0 5.2e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001266890.1_29628001_2 - 1.2e-14 54.1 0.0 3.4e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase CENP-B_N PF04218.11 001266890.1_29628001_2 - 0.11 12.1 0.4 0.28 10.7 0.4 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain IncA PF04156.12 001266890.1_29628001_2 - 2.3 7.9 8.4 4.2 7.0 8.4 1.3 1 0 0 1 1 1 0 IncA protein SNF PF00209.16 001266276.1_29627001_3 - 9.6e-216 717.4 33.3 1.2e-215 717.0 33.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family MFS_1_like PF12832.5 001194592.2_29625001_3 - 2.8e-43 148.1 3.3 3.7e-43 147.7 3.3 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.14 001194592.2_29625001_3 - 2.8e-09 36.3 26.3 1.1e-07 31.0 17.9 3.5 2 1 0 3 3 3 2 Major Facilitator Superfamily TNFR_c6 PF00020.16 001267073.1_49824001_2 - 3e-08 33.8 15.1 7.4e-06 26.2 10.4 4.9 4 0 0 4 4 4 2 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.11 001267073.1_49824001_2 - 5.9 6.6 30.5 0.041 13.5 11.9 3.7 2 1 1 3 3 3 0 Putative ephrin-receptor like Patched PF02460.16 001077689.1_29628001_1 - 2.3e-75 254.1 9.3 3.2e-43 147.8 0.1 2.3 2 1 0 2 2 2 2 Patched family NPC1_N PF16414.3 001077689.1_29628001_1 - 8.2e-72 241.5 4.2 1.6e-71 240.6 4.2 1.5 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.6 001077689.1_29628001_1 - 1.1e-53 181.1 1.3 1.1e-53 181.1 1.3 3.1 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.13 001077689.1_29628001_1 - 0.00053 18.9 6.4 0.00053 18.9 6.4 2.2 3 0 0 3 3 3 1 MMPL family Folate_rec PF03024.12 001077689.1_29628001_1 - 1.6 8.4 10.3 0.037 13.8 3.0 1.9 2 0 0 2 2 2 0 Folate receptor family DEAD PF00270.27 001260872.1_29627001_3 - 7.4e-54 182.0 0.0 3.5e-53 179.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001260872.1_29627001_3 - 4.9e-31 107.3 0.0 2e-30 105.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001260872.1_29627001_3 - 0.01 15.7 0.0 0.04 13.8 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3698 PF12479.6 001260872.1_29627001_3 - 0.33 11.4 1.3 1.2 9.6 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Pkinase PF00069.23 001261653.1_29626001_1 - 1e-66 224.9 0.0 1.3e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001261653.1_29626001_1 - 5.2e-45 153.6 0.0 7.3e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.26 001261653.1_29626001_1 - 8e-16 58.1 0.1 1.7e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.4 001261653.1_29626001_1 - 2.2e-07 30.4 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001261653.1_29626001_1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001261653.1_29626001_1 - 0.26 11.0 1.2 2.8 7.7 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-CCHC_2 PF13696.4 001261653.1_29626001_1 - 0.29 10.8 3.0 0.6 9.8 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle SPAN-X PF07458.10 001261653.1_29626001_2 - 0.26 11.6 0.7 0.49 10.7 0.7 1.4 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome CDI PF02234.17 001194722.2_29625001_1 - 1.4e-17 63.5 0.1 2.5e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Nore1-SARAH PF16517.3 001265673.1_29625001_3 - 1.6e-12 47.0 5.3 3.9e-12 45.8 5.3 1.7 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RA PF00788.21 001265673.1_29625001_3 - 2e-12 47.5 0.0 5.1e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ets PF00178.20 001244456.1_49825001_3 - 1.5e-36 124.6 1.3 8.8e-36 122.1 0.4 2.3 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.14 001244456.1_49825001_3 - 1.8e-25 88.6 0.0 3.5e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.15 001244456.1_49825001_3 - 0.047 13.7 0.2 0.34 10.9 0.1 2.3 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Y_phosphatase PF00102.25 001265681.1_29626001_2 - 1.9e-74 250.0 0.6 3.1e-74 249.4 0.6 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.18 001265681.1_29626001_2 - 0.00082 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.4 001265681.1_29626001_2 - 0.032 14.1 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Rb_C PF08934.8 001285967.1_49827001_1 - 3.6e-83 276.7 4.0 1.6e-82 274.6 2.4 2.3 2 0 0 2 2 2 1 Rb C-terminal domain RB_A PF01858.15 001285967.1_49827001_1 - 1.6e-76 256.4 3.2 2e-76 256.1 1.4 2.1 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.18 001285967.1_49827001_1 - 2.8e-35 121.1 9.4 9.1e-34 116.2 5.7 3.4 3 0 0 3 3 3 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.6 001285967.1_49827001_1 - 2.1e-11 43.4 3.1 2.1e-11 43.4 3.1 4.1 4 1 0 4 4 4 2 Domain of unknown function (DUF3452) Ribosomal_60s PF00428.17 001285967.1_49827001_1 - 5.7 7.4 7.6 14 6.2 7.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PRIMA1 PF16101.3 001285967.1_49827001_2 - 0.52 10.2 11.3 1.1 9.2 11.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ank_2 PF12796.5 001042433.2_29625001_2 - 1.2e-42 144.2 4.0 9.6e-12 45.2 0.3 5.6 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001042433.2_29625001_2 - 4e-37 126.0 1.5 3.2e-08 33.8 0.0 6.7 4 2 3 7 7 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.4 001042433.2_29625001_2 - 7.1e-35 118.4 2.7 1.6e-10 40.9 0.1 5.7 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.4 001042433.2_29625001_2 - 2.5e-34 113.3 4.7 0.0011 19.2 0.0 9.6 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.28 001042433.2_29625001_2 - 1.3e-32 110.7 3.0 2.2e-05 24.5 0.1 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ribonuc_2-5A PF06479.10 001042433.2_29625001_2 - 2.5e-26 92.2 2.2 5.1e-26 91.2 2.2 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.23 001042433.2_29625001_2 - 2.1e-15 56.7 0.0 3e-14 52.9 0.1 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001042433.2_29625001_2 - 3.5e-09 36.2 0.0 7.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001042433.2_29625001_2 - 0.004 16.4 0.0 0.0098 15.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001042433.2_29625001_2 - 0.011 15.2 0.2 0.06 12.8 0.1 2.2 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.18 001042433.2_29625001_2 - 0.012 15.1 0.3 0.012 15.1 0.3 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase IFT20 PF14931.4 001042433.2_29625001_2 - 0.068 13.2 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 RUN PF02759.17 001042433.2_29625001_2 - 0.11 12.4 0.0 0.36 10.6 0.0 1.9 1 0 0 1 1 1 0 RUN domain UQ_con PF00179.24 001261204.1_29625001_2 - 1.3e-51 173.8 0.0 1.8e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LRR_6 PF13516.4 001243371.1_49826001_1 - 0.041 13.8 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 Leucine Rich repeat Mod_r PF07200.11 001243371.1_49826001_2 - 2.2e-36 125.0 13.6 2.8e-36 124.7 13.6 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Tex_N PF09371.8 001243371.1_49826001_2 - 2.8 7.3 6.2 4.2 6.7 6.2 1.1 1 0 0 1 1 1 0 Tex-like protein N-terminal domain EBP50_C PF09007.9 001266178.1_29624001_1 - 5.8e-43 146.9 9.3 5.8e-43 146.9 9.3 1.9 2 0 0 2 2 2 1 EBP50, C-terminal PDZ PF00595.22 001266178.1_29624001_1 - 9.1e-30 102.7 0.0 1.9e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001266178.1_29624001_1 - 2.1e-15 56.6 0.2 7.6e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain GRASP55_65 PF04495.12 001266178.1_29624001_1 - 0.00079 19.6 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain Bax1-I PF01027.18 001278564.1_39524001_1 - 6.3e-35 120.8 30.2 7.6e-35 120.5 30.2 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Hum_adeno_E3A PF05393.9 001278564.1_39524001_1 - 2 8.3 5.4 0.76 9.7 0.3 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein TMEM100 PF16311.3 001278564.1_39524001_1 - 6.3 6.3 7.0 11 5.4 7.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 ECH_1 PF00378.18 001283888.1_29523001_1 - 1.2e-100 335.8 2.1 1.6e-100 335.5 2.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.3 001283888.1_29523001_1 - 9.3e-38 130.4 2.9 1.4e-35 123.2 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.16 001283888.1_29523001_1 - 0.00085 19.2 0.2 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 Peptidase family S49 Acetyltransf_3 PF13302.5 001195360.1_49823001_3 - 7.7e-27 94.5 0.0 1.2e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.23 001195360.1_49823001_3 - 6.6e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.8 001195360.1_49823001_3 - 6.8e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.4 001195360.1_49823001_3 - 2.9e-05 23.7 0.1 7e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 001195360.1_49823001_3 - 0.028 14.7 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-DHHC PF01529.18 001266260.1_29625001_1 - 1.2e-36 125.6 7.9 1.2e-36 125.6 7.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase HRG PF16954.3 001266260.1_29625001_1 - 1.4 9.3 5.8 9.1 6.7 2.9 2.8 1 1 1 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene HSP90 PF00183.16 001244433.1_49826001_3 - 1.5e-242 805.9 27.7 2e-242 805.5 27.7 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.24 001244433.1_49826001_3 - 2.1e-13 50.7 0.0 4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001244433.1_49826001_3 - 3.4e-10 39.8 0.1 9e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.12 001244433.1_49826001_3 - 7.8 4.5 14.0 14 3.7 14.0 1.3 1 0 0 1 1 1 0 CDC45-like protein EGF PF00008.25 001244418.1_49827001_2 - 1.7e-31 108.0 141.2 2.5e-07 30.7 6.5 10.1 9 1 0 9 9 9 7 EGF-like domain DSL PF01414.17 001244418.1_49827001_2 - 5.9e-23 80.7 3.4 5.9e-23 80.7 3.4 7.2 5 2 3 8 8 8 1 Delta serrate ligand hEGF PF12661.5 001244418.1_49827001_2 - 1.1e-18 67.0 115.8 6.1e-06 26.6 7.0 10.8 10 0 0 10 10 10 7 Human growth factor-like EGF MNNL PF07657.11 001244418.1_49827001_2 - 3.6e-18 65.2 0.2 3.6e-18 65.2 0.2 3.9 4 0 0 4 4 4 1 N terminus of Notch ligand EGF_2 PF07974.11 001244418.1_49827001_2 - 2.3e-10 40.5 153.3 0.0026 18.0 11.7 10.7 10 0 0 10 10 10 7 EGF-like domain DUF4381 PF14316.4 001244418.1_49827001_2 - 0.002 18.2 0.2 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) Mito_carr PF00153.25 001194300.2_29624001_2 - 5.1e-71 234.5 2.1 4.2e-24 84.2 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein GTSE1_N PF15259.4 001266394.1_29624001_1 - 1.3e-09 38.2 0.0 4.6e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 G-2 and S-phase expressed 1 TAF1D PF15333.4 001257644.1_29623001_2 - 2e-96 321.8 8.7 2.8e-96 321.4 8.7 1.2 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D Ras PF00071.20 001194129.2_29629001_1 - 2.2e-47 160.6 0.0 3.2e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001194129.2_29629001_1 - 8.6e-16 58.1 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.21 001194129.2_29629001_1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001194129.2_29629001_1 - 0.021 14.6 0.1 7.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 zf-C2H2 PF00096.24 001284829.1_29523001_1 - 1.9e-14 53.1 23.0 9.3e-05 22.5 1.1 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001284829.1_29523001_1 - 3.4e-11 42.9 12.2 1.5e-07 31.4 2.8 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 001284829.1_29523001_1 - 4.5e-08 33.1 20.1 0.0025 18.4 2.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.3 001284829.1_29523001_1 - 0.0074 16.8 6.3 0.059 13.9 0.3 3.2 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2H2_6 PF13912.4 001284829.1_29523001_1 - 0.027 14.3 1.4 0.027 14.3 1.4 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.5 001284829.1_29523001_1 - 0.037 14.3 11.1 0.086 13.1 0.7 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.3 001284829.1_29523001_1 - 0.14 12.4 5.4 0.38 10.9 5.0 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon IBR PF01485.19 001284829.1_29523001_1 - 0.83 9.8 6.6 4.4 7.5 6.6 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-Di19 PF05605.10 001284829.1_29523001_1 - 1 9.6 9.0 0.35 11.0 2.5 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding WD40 PF00400.30 001261139.1_29628001_3 - 0.00076 20.1 10.5 5.4 7.9 0.1 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001261139.1_29628001_3 - 0.11 12.7 0.0 38 4.5 0.0 3.5 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.19 001244571.1_49822001_1 - 2.5e-12 46.6 8.1 4e-12 45.9 8.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001244571.1_49822001_1 - 3.2e-10 39.8 11.9 4.8e-10 39.2 11.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001244571.1_49822001_1 - 1.2e-06 28.8 8.1 2.4e-06 27.8 8.1 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor PKK PF12474.6 001244571.1_49822001_1 - 0.0032 17.4 6.8 0.0045 16.9 6.8 1.1 1 0 0 1 1 1 1 Polo kinase kinase HALZ PF02183.16 001244571.1_49822001_1 - 0.028 14.5 3.7 0.046 13.8 3.7 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Phlebovirus_NSM PF07246.9 001244571.1_49822001_1 - 0.042 13.1 1.0 0.057 12.7 1.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AAA_11 PF13086.4 001244571.1_49822001_1 - 0.067 12.8 2.6 0.089 12.4 2.6 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.10 001244571.1_49822001_1 - 0.11 11.7 3.1 0.14 11.4 3.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMCO5 PF14992.4 001244571.1_49822001_1 - 0.15 11.5 4.2 0.19 11.2 4.2 1.1 1 0 0 1 1 1 0 TMCO5 family IncA PF04156.12 001244571.1_49822001_1 - 0.69 9.5 4.2 0.93 9.1 4.2 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.13 001244571.1_49822001_1 - 2.2 8.0 6.3 4 7.1 6.3 1.5 1 1 0 1 1 1 0 Septum formation initiator LRRNT PF01462.16 001141989.1_49822001_1 - 1.1e-07 31.2 1.1 1.1e-07 31.2 1.1 2.6 3 1 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.4 001141989.1_49822001_1 - 1.7e-06 27.6 0.3 3.6e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.5 001141989.1_49822001_1 - 0.0016 18.7 0.4 0.0031 17.7 0.2 1.6 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRRCT PF01463.22 001141989.1_49822001_1 - 0.033 14.6 0.4 0.12 12.8 0.2 2.1 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain Serpin PF00079.18 001261087.1_29625001_3 - 7.5e-94 314.9 0.0 8.8e-94 314.7 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) EPTP PF03736.15 001261057.1_29625001_3 - 1.9e-68 226.1 20.5 2e-12 46.8 0.1 7.5 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.4 001261057.1_29625001_3 - 5.1e-22 77.3 12.5 2.8e-15 55.7 5.1 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.5 001261057.1_29625001_3 - 1.4e-07 31.6 14.6 0.00026 21.1 3.5 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001261057.1_29625001_3 - 3.1e-07 30.3 1.5 3.1e-07 30.3 1.5 2.2 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001261057.1_29625001_3 - 0.0063 15.9 0.1 0.016 14.6 0.1 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.31 001261057.1_29625001_3 - 0.74 10.4 10.1 3.7 8.2 0.5 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat E1-E2_ATPase PF00122.18 001266673.1_29627001_3 - 1e-57 194.9 1.7 1e-57 194.9 1.7 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.19 001266673.1_29627001_3 - 2.2e-44 151.2 0.3 2.2e-44 151.2 0.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.4 001266673.1_29627001_3 - 1.1e-23 82.9 0.0 2.5e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.24 001266673.1_29627001_3 - 6.2e-19 69.0 0.1 9.3e-16 58.6 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 001266673.1_29627001_3 - 6.9e-18 64.0 0.0 1.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.10 001266673.1_29627001_3 - 7.9e-06 25.7 0.9 0.00089 18.9 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tetraspannin PF00335.18 001266673.1_29627001_3 - 0.21 11.2 4.4 1.4 8.6 0.4 2.8 3 0 0 3 3 3 0 Tetraspanin family ACOX PF01756.17 001132607.1_43525001_1 - 2e-62 209.8 1.6 2.7e-62 209.4 0.3 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.4 001132607.1_43525001_1 - 4.8e-28 98.1 0.1 1.2e-27 96.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.17 001132607.1_43525001_1 - 1.1e-08 35.0 0.0 2.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.22 001132607.1_43525001_1 - 0.0037 17.4 0.1 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DENN PF02141.19 001261060.1_29625001_2 - 2.7e-58 196.8 1.8 4.2e-58 196.2 1.8 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.16 001261060.1_29625001_2 - 5.3e-15 55.9 0.0 1.3e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.17 001261060.1_29625001_2 - 5.3e-11 42.2 2.0 1.4e-10 40.8 2.0 1.7 1 0 0 1 1 1 1 dDENN domain Zip PF02535.20 001286991.1_09023001_3 - 3.4e-54 184.2 5.9 1.5e-38 132.8 3.2 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Glyco_hydro_31 PF01055.24 001194711.1_29629001_2 - 3.5e-150 500.9 0.5 4.4e-150 500.6 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.4 001194711.1_29629001_2 - 9.5e-25 86.6 0.1 3.8e-23 81.5 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.2 001194711.1_29629001_2 - 1.6e-05 25.0 0.0 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) IL8 PF00048.18 001024589.1_49821001_2 - 2.7e-20 72.1 0.4 4.4e-20 71.4 0.4 1.4 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like AgrB PF04647.13 001132813.1_43525001_1 - 0.096 11.9 0.5 0.14 11.3 0.5 1.1 1 0 0 1 1 1 0 Accessory gene regulator B HEAT PF02985.20 001132813.1_43525001_2 - 1.1e-46 152.7 25.3 0.0002 21.2 0.0 13.4 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.4 001132813.1_43525001_2 - 3e-42 142.8 7.0 2e-14 53.6 0.0 7.6 2 1 6 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.5 001132813.1_43525001_2 - 3.7e-14 52.9 1.7 0.059 13.8 0.0 7.4 3 2 4 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.5 001132813.1_43525001_2 - 4.5e-11 42.9 8.8 0.0029 17.5 0.6 4.4 1 1 3 4 4 4 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.4 001132813.1_43525001_2 - 1.2e-10 41.4 11.5 0.017 15.4 0.1 8.3 8 3 2 10 10 10 3 HEAT-like repeat CLASP_N PF12348.6 001132813.1_43525001_2 - 9.9e-08 31.7 0.9 0.082 12.3 0.3 5.4 2 2 1 4 4 4 1 CLASP N terminal Adaptin_N PF01602.18 001132813.1_43525001_2 - 3.9e-07 28.9 8.6 0.018 13.5 4.2 4.0 3 1 1 4 4 4 3 Adaptin N terminal region M11L PF11099.6 001132813.1_43525001_2 - 0.00013 22.1 0.3 0.018 15.2 0.0 3.0 2 1 0 2 2 2 1 Apoptosis regulator M11L like TAF6_C PF07571.11 001132813.1_43525001_2 - 0.00018 21.7 0.1 0.73 10.1 0.0 4.5 4 1 1 5 5 5 1 TAF6 C-terminal HEAT repeat domain IFRD PF05004.11 001132813.1_43525001_2 - 0.013 14.5 1.7 3.1 6.7 0.1 3.7 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) RELT PF12606.6 001193775.1_29622001_1 - 2.9e-22 77.6 0.7 4.6e-22 77.0 0.7 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 UPF0767 PF15990.3 001193775.1_29622001_1 - 0.06 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 UPF0767 family Lipid_DES PF08557.8 001136489.1_39523001_1 - 2.2e-20 71.7 0.2 4.5e-20 70.7 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.22 001136489.1_39523001_1 - 5.2e-20 72.2 15.0 5.2e-20 72.2 15.0 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Pkinase_Tyr PF07714.15 001280714.1_39524001_3 - 1.5e-37 129.2 0.0 2.3e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001280714.1_39524001_3 - 3.2e-37 128.2 0.0 5.9e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.10 001280714.1_39524001_3 - 7.1e-16 57.3 0.7 1.4e-15 56.3 0.7 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.21 001280714.1_39524001_3 - 5.1e-12 46.6 13.5 5.1e-12 46.6 13.5 1.8 2 0 0 2 2 2 1 Activin types I and II receptor domain FTA2 PF13095.4 001280714.1_39524001_3 - 0.035 13.6 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.21 001280714.1_39524001_3 - 0.18 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_8 PF13855.4 001265758.1_29627001_2 - 1.3e-24 85.5 9.1 6.8e-14 51.2 1.6 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 001265758.1_29627001_2 - 7.1e-07 29.3 6.3 0.016 15.5 0.3 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001265758.1_29627001_2 - 3.5e-06 26.9 0.0 6.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001265758.1_29627001_2 - 0.04 13.3 0.3 0.96 8.8 0.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeat CD34_antigen PF06365.10 001265758.1_29627001_2 - 0.21 11.1 0.1 0.36 10.3 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Pkinase PF00069.23 001168991.1_40423001_1 - 5.1e-68 229.1 0.0 6.4e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001168991.1_40423001_1 - 3.6e-32 111.5 0.0 5.3e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001168991.1_40423001_1 - 0.0011 18.3 0.1 0.0045 16.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001168991.1_40423001_1 - 0.025 14.4 0.1 0.097 12.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.4 001168991.1_40423001_1 - 0.099 12.1 0.0 7 6.1 0.0 2.4 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 BEX PF04538.10 001243430.1_49823001_2 - 1.2e-47 161.4 40.9 7e-43 146.1 15.6 2.9 1 1 1 2 2 2 2 Brain expressed X-linked like family RasGEF PF00617.17 001261700.2_29627001_1 - 2.8e-45 154.5 0.7 4.1e-45 153.9 0.7 1.3 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.20 001261700.2_29627001_1 - 1e-12 47.6 9.3 1e-12 47.6 9.3 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_6 PF13405.4 001261700.2_29627001_1 - 4.6e-09 35.4 1.0 0.00026 20.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.30 001261700.2_29627001_1 - 6.5e-09 34.6 5.0 0.00039 19.6 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.4 001261700.2_29627001_1 - 8.8e-09 35.6 1.2 0.00097 19.4 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.4 001261700.2_29627001_1 - 1e-07 31.0 0.4 0.021 14.2 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.4 001261700.2_29627001_1 - 0.00012 21.6 1.4 0.17 11.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair RasGEF_N PF00618.18 001261700.2_29627001_1 - 0.00015 21.9 0.2 0.00051 20.1 0.1 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Lectin_leg-like PF03388.11 001261072.1_29629001_1 - 4.1e-92 307.5 0.0 5.7e-92 307.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Golgin_A5 PF09787.7 001261072.1_29629001_1 - 2.6 7.3 11.4 4.3 6.6 11.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Snapin_Pallidin PF14712.4 001261072.1_29629001_1 - 7.8 6.9 6.2 27 5.2 0.4 2.7 2 0 0 2 2 2 0 Snapin/Pallidin DFF-C PF09033.8 001260683.1_29623001_2 - 6.9e-71 237.4 11.8 6.9e-71 237.4 11.8 1.8 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain CIDE-N PF02017.13 001260683.1_29623001_2 - 9.9e-28 95.9 0.0 6.1e-26 90.1 0.0 2.4 2 0 0 2 2 2 1 CIDE-N domain SAPIS-gp6 PF16722.3 001260683.1_29623001_2 - 0.65 10.3 3.4 8.2 6.8 0.8 2.7 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus COG2 PF06148.9 001260683.1_29623001_2 - 1.3 8.9 5.8 0.17 11.8 1.6 1.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NUFIP2 PF15293.4 001261811.1_29629001_3 - 2.8e-293 974.2 26.3 3.4e-293 973.9 26.3 1.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 SHMT PF00464.17 001257431.1_29624001_1 - 3e-212 704.3 0.0 3.5e-212 704.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.19 001257431.1_29624001_1 - 0.001 18.2 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.15 001257431.1_29624001_1 - 0.065 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ETF PF01012.19 001261119.1_29623001_2 - 4.1e-40 137.5 2.1 6.2e-40 136.9 2.1 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.17 001261119.1_29623001_2 - 2.5e-37 126.6 1.4 3.4e-37 126.2 0.4 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain zf-C2H2 PF00096.24 001126342.1_39522001_1 - 6.8e-26 89.1 33.2 4.6e-06 26.7 0.4 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001126342.1_39522001_1 - 1.6e-20 71.9 32.9 0.00026 21.4 1.8 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001126342.1_39522001_1 - 2.2e-18 65.6 31.8 3.4e-07 30.3 0.4 5.8 5 1 0 5 5 5 5 Zinc-finger double domain zf-C2H2_6 PF13912.4 001126342.1_39522001_1 - 1.6e-14 53.3 27.1 0.00032 20.4 3.1 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001126342.1_39522001_1 - 1.8e-13 50.3 21.7 0.005 17.0 0.2 5.7 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001126342.1_39522001_1 - 7.6e-09 35.5 27.6 0.098 12.9 1.7 5.6 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-Di19 PF05605.10 001126342.1_39522001_1 - 5.4e-06 26.5 16.0 0.032 14.4 1.2 3.6 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.13 001126342.1_39522001_1 - 1.4e-05 24.9 27.6 0.29 11.1 1.0 5.5 2 1 3 5 5 5 4 BED zinc finger zinc_ribbon_15 PF17032.3 001126342.1_39522001_1 - 0.011 16.3 1.3 0.011 16.3 1.3 2.9 2 1 0 2 2 1 0 zinc-ribbon family zf-H2C2_5 PF13909.4 001126342.1_39522001_1 - 0.017 14.7 1.6 0.017 14.7 1.6 5.3 5 1 0 5 5 4 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.5 001126342.1_39522001_1 - 0.019 15.2 22.0 3.3 8.0 0.8 5.0 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.4 001126342.1_39522001_1 - 0.047 13.5 19.3 3.2 7.6 0.1 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type PyrI_C PF02748.13 001126342.1_39522001_1 - 0.059 13.2 16.0 2 8.3 1.4 4.9 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.8 001126342.1_39522001_1 - 0.064 13.3 18.4 0.52 10.4 1.9 4.2 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.5 001126342.1_39522001_1 - 0.42 10.5 24.3 1 9.2 0.5 4.2 4 0 0 4 4 4 0 Transposase zinc-ribbon domain zf-AN1 PF01428.14 001126342.1_39522001_1 - 1.6 8.9 26.3 8 6.6 1.9 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger zf-CHY PF05495.10 001126342.1_39522001_1 - 4.8 7.7 25.0 1.2 9.6 5.9 2.7 2 1 0 2 2 2 0 CHY zinc finger IL8 PF00048.18 001129903.1_39521001_2 - 1.3e-08 34.7 2.2 1.3e-08 34.7 2.2 1.7 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like 7tm_1 PF00001.19 001198700.1_29624001_3 - 3.1e-87 292.1 0.0 3.8e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001198700.1_29624001_3 - 3e-12 46.3 4.1 1.9e-07 30.6 1.7 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001198700.1_29624001_3 - 5e-05 23.0 7.3 0.00015 21.5 1.3 2.7 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001198700.1_29624001_3 - 5.1e-05 22.6 2.2 5.1e-05 22.6 2.2 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Copine PF07002.14 001260641.1_29625001_3 - 4.9e-88 294.1 0.0 6.6e-88 293.7 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.28 001260641.1_29625001_3 - 4.1e-27 94.3 0.0 3.2e-13 49.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.7 001260641.1_29625001_3 - 3.7e-05 23.8 0.0 7.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus LRR_8 PF13855.4 001279752.1_24226001_1 - 1.8e-79 261.3 95.2 1.8e-12 46.7 5.9 11.2 7 4 3 11 11 11 11 Leucine rich repeat LRR_4 PF12799.5 001279752.1_24226001_1 - 4.3e-35 118.9 98.5 1.9e-05 24.8 5.9 13.6 7 3 6 15 15 15 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001279752.1_24226001_1 - 9.4e-22 77.2 27.7 1.1e-06 28.5 6.8 6.1 2 1 5 7 7 7 6 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001279752.1_24226001_1 - 2.3e-13 49.9 35.6 5.3e-06 25.9 1.4 7.4 2 1 7 9 9 9 6 Leucine-rich repeat LRR_1 PF00560.31 001279752.1_24226001_1 - 1.3e-12 46.1 80.8 1.5 9.4 0.1 20.8 21 1 0 21 21 21 5 Leucine Rich Repeat LRR_6 PF13516.4 001279752.1_24226001_1 - 1.6e-09 36.9 87.3 0.33 11.0 0.1 19.5 20 0 0 20 20 20 7 Leucine Rich repeat TIR PF01582.18 001279752.1_24226001_1 - 1.1e-08 34.9 0.7 2.1e-08 34.0 0.7 1.4 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.16 001279752.1_24226001_1 - 0.0041 16.6 0.3 0.0041 16.6 0.3 1.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.22 001279752.1_24226001_1 - 0.0082 16.5 0.1 0.048 14.1 0.1 2.5 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain TIR_2 PF13676.4 001279752.1_24226001_1 - 0.076 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 TIR domain Dysbindin PF04440.14 001168736.1_40423001_1 - 2.4e-24 86.0 0.0 3.9e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) Peptidase_C2 PF00648.19 001260667.1_29627001_3 - 4.4e-128 426.3 0.0 6.2e-128 425.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.20 001260667.1_29627001_3 - 7e-55 185.1 0.0 1.1e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.30 001260667.1_29627001_3 - 8.4e-10 37.4 2.8 0.019 14.3 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.4 001260667.1_29627001_3 - 3.9e-09 35.6 1.0 0.062 13.1 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.4 001260667.1_29627001_3 - 2.6e-08 33.4 1.2 3.5e-07 29.8 0.2 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.4 001260667.1_29627001_3 - 9.9e-05 22.6 6.7 1.3 9.5 1.1 4.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.4 001260667.1_29627001_3 - 0.24 10.9 1.3 3.5 7.2 0.1 3.1 3 0 0 3 3 3 0 EF hand SSXT PF05030.10 001284895.1_29525001_2 - 1.7e-24 85.1 4.0 2.9e-24 84.3 4.0 1.3 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Nramp PF01566.16 001266689.1_29627001_3 - 2.9e-119 398.1 13.6 5.3e-119 397.2 13.6 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein GIT1_C PF12205.6 001266994.1_29627001_1 - 1.9e-48 163.3 1.3 1.9e-48 163.3 1.3 2.4 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_CC PF16559.3 001266994.1_29627001_1 - 4e-29 100.3 7.7 1e-28 99.0 7.7 1.7 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor ArfGap PF01412.16 001266994.1_29627001_1 - 4.4e-28 97.5 0.0 4.4e-28 97.5 0.0 2.2 3 0 0 3 3 2 1 Putative GTPase activating protein for Arf GIT_SHD PF08518.9 001266994.1_29627001_1 - 6.5e-27 92.7 1.6 9.5e-14 50.6 0.1 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Ank_2 PF12796.5 001266994.1_29627001_1 - 7.8e-09 35.9 0.0 2.1e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001266994.1_29627001_1 - 1.5e-07 31.5 0.0 7e-07 29.3 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.4 001266994.1_29627001_1 - 9.8e-07 29.1 0.0 0.00025 21.4 0.0 3.1 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank PF00023.28 001266994.1_29627001_1 - 0.00037 20.7 0.0 0.0028 17.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Shugoshin_N PF07558.9 001266994.1_29627001_1 - 0.025 14.3 8.0 0.066 13.0 8.0 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TTRAP PF14203.4 001266994.1_29627001_1 - 0.056 13.3 0.1 0.33 10.8 0.1 2.3 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Sen15 PF09631.8 001266994.1_29627001_1 - 0.058 13.6 0.1 0.23 11.7 0.0 2.0 2 0 0 2 2 1 0 Sen15 protein zf-RRN7 PF11781.6 001266994.1_29627001_1 - 0.12 12.0 3.1 0.24 11.0 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DMPK_coil PF08826.8 001266994.1_29627001_1 - 0.13 12.2 2.1 0.5 10.4 2.1 2.0 1 0 0 1 1 1 0 DMPK coiled coil domain like K-box PF01486.15 001266994.1_29627001_1 - 0.13 12.3 3.4 0.56 10.3 3.4 2.1 1 0 0 1 1 1 0 K-box region Ank_3 PF13606.4 001266994.1_29627001_1 - 0.17 12.4 0.0 2.6 8.8 0.0 2.9 3 0 0 3 3 2 0 Ankyrin repeat GAS PF13851.4 001266994.1_29627001_1 - 0.38 10.0 8.9 0.018 14.3 3.3 1.6 2 0 0 2 2 1 0 Growth-arrest specific micro-tubule binding DUF4482 PF14818.4 001266994.1_29627001_1 - 0.51 11.1 4.0 0.33 11.7 0.7 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4482) DUF5094 PF17015.3 001266994.1_29627001_1 - 1.8 8.5 6.1 4.6 7.2 6.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) T7SS_ESX_EspC PF10824.6 001266994.1_29627001_1 - 1.8 8.9 4.7 1.1 9.6 0.1 2.7 3 0 0 3 3 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF972 PF06156.11 001266994.1_29627001_1 - 2 8.9 6.2 1.3 9.6 3.2 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF972) DUF3347 PF11827.6 001266994.1_29627001_1 - 2.9 7.9 7.6 8.7 6.4 7.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) ATP_synt_H PF05493.11 001283978.1_29523001_1 - 6.3e-23 80.9 4.9 1.4e-22 79.7 4.9 1.7 1 0 0 1 1 1 1 ATP synthase subunit H LMBR1 PF04791.14 001194754.1_29625001_2 - 4.3e-77 260.0 29.7 8.4e-51 173.3 12.0 2.8 2 1 0 2 2 2 2 LMBR1-like membrane protein Oxidored_q4 PF00507.17 001194754.1_29625001_2 - 0.024 14.6 3.2 0.088 12.8 3.2 2.0 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 SH PF01445.15 001194754.1_29625001_2 - 0.076 12.9 0.1 0.48 10.3 0.1 2.4 1 0 0 1 1 1 0 Viral small hydrophobic protein AA_permease_2 PF13520.4 001266615.1_29629001_3 - 2.8e-49 168.0 22.3 2.8e-49 168.0 22.3 2.5 3 0 0 3 3 3 1 Amino acid permease AA_permease PF00324.19 001266615.1_29629001_3 - 7.3e-40 136.8 20.2 7.3e-40 136.8 20.2 2.3 3 0 0 3 3 3 1 Amino acid permease AA_permease_C PF13906.4 001266615.1_29629001_3 - 2.6e-24 84.9 7.9 2.6e-24 84.9 7.9 3.1 3 0 0 3 3 3 1 C-terminus of AA_permease AA_permease_2 PF13520.4 001266291.1_29627001_2 - 2.2e-58 197.9 38.1 4e-58 197.1 38.1 1.4 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.19 001266291.1_29627001_2 - 3.8e-31 108.1 34.9 6.5e-31 107.3 34.9 1.3 1 0 0 1 1 1 1 Amino acid permease DoxX_2 PF13564.4 001266291.1_29627001_2 - 2.7 8.0 6.9 1.7 8.6 0.2 3.1 2 1 0 2 2 2 0 DoxX-like family Mito_carr PF00153.25 001261376.1_29628001_1 - 6.7e-71 234.2 0.2 6e-25 86.9 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.30 001261376.1_29628001_1 - 3.3e-10 38.6 1.9 0.0087 15.4 0.2 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.4 001261376.1_29628001_1 - 7.8e-09 34.7 3.2 0.0099 15.6 0.1 5.5 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.4 001261376.1_29628001_1 - 5.6e-08 33.0 1.7 0.021 15.2 0.0 4.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.4 001261376.1_29628001_1 - 0.00055 19.2 0.6 1.6 8.2 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.4 001261376.1_29628001_1 - 0.017 14.8 0.0 1.6 8.4 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain pair zf-C2H2 PF00096.24 001261280.1_29623001_2 - 8.4e-16 57.3 23.0 2.7e-06 27.4 2.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001261280.1_29623001_2 - 2.2e-12 46.7 21.7 5.6e-09 35.9 1.1 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001261280.1_29623001_2 - 3e-08 33.7 20.0 0.0031 18.1 1.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.5 001261280.1_29623001_2 - 0.0044 17.2 5.2 0.5 10.7 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001261280.1_29623001_2 - 0.026 14.3 8.5 0.05 13.4 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1071 PF06378.9 001261280.1_29623001_2 - 0.16 11.4 0.2 0.29 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) zf-C2H2_jaz PF12171.6 001261280.1_29623001_2 - 0.26 11.5 3.8 13 6.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.3 001261280.1_29623001_2 - 1.8 8.5 4.4 5.3 7.0 0.2 2.0 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.3 001261280.1_29623001_2 - 2.9 8.5 7.8 7.2 7.2 0.7 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-CCHC_3 PF13917.4 001261537.1_29625001_1 - 6.1e-07 29.2 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Zinc knuckle DDHD PF02862.15 001261537.1_29625001_1 - 2.6 8.0 12.4 4.9 7.1 12.4 1.4 1 0 0 1 1 1 0 DDHD domain Med19 PF10278.7 001261537.1_29625001_1 - 6.8 6.4 34.6 13 5.5 34.6 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Hormone_recep PF00104.28 001205153.1_39529001_1 - 4.2e-40 137.4 0.0 6.8e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001205153.1_39529001_1 - 4.1e-29 100.7 18.4 4.1e-29 100.7 18.4 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) MISS PF15822.3 001260990.1_29627001_3 - 8.4e-119 395.6 124.8 8.4e-119 395.6 124.8 1.8 2 0 0 2 2 2 1 MAPK-interacting and spindle-stabilising protein-like EGF PF00008.25 001242720.1_37623001_1 - 2.6e-21 75.4 91.2 2.2e-08 34.1 10.3 7.7 7 0 0 7 7 7 5 EGF-like domain EGF_2 PF07974.11 001242720.1_37623001_1 - 7.7e-06 26.0 99.8 0.024 14.9 9.9 6.9 7 0 0 7 7 7 6 EGF-like domain hEGF PF12661.5 001242720.1_37623001_1 - 0.0002 21.8 87.2 0.0021 18.5 5.5 8.1 8 0 0 8 8 8 4 Human growth factor-like EGF EGF_MSP1_1 PF12946.5 001242720.1_37623001_1 - 0.018 14.9 5.2 0.018 14.9 5.2 4.7 5 0 0 5 5 5 0 MSP1 EGF domain 1 Laminin_EGF PF00053.22 001242720.1_37623001_1 - 1.3 9.1 67.9 1.9 8.6 7.5 6.8 3 2 3 6 6 6 0 Laminin EGF domain Bromodomain PF00439.23 001132948.1_43529001_2 - 2.8e-10 40.0 0.1 7.2e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.15 001132948.1_43529001_2 - 7.9e-10 38.9 0.4 7.9e-10 38.9 0.4 3.0 3 0 0 3 3 3 1 PWWP domain Ig_2 PF13895.4 001040675.1_29624001_3 - 4.3e-32 110.2 0.7 1.1e-13 51.2 0.1 4.2 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.4 001040675.1_29624001_3 - 1.5e-25 89.5 2.1 2.9e-06 27.7 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.23 001040675.1_29624001_3 - 9e-18 64.1 0.2 5.5e-05 23.1 0.0 4.6 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.15 001040675.1_29624001_3 - 3.3e-05 23.9 2.0 1.8 8.6 0.0 5.7 4 2 2 6 6 6 1 Immunoglobulin V-set domain C2-set_2 PF08205.10 001043593.1_29623001_1 - 6.2e-18 64.5 2.6 8e-18 64.2 0.2 2.4 2 1 1 3 3 3 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001043593.1_29623001_1 - 7.2e-16 58.0 0.0 1.2e-05 25.3 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001043593.1_29623001_1 - 1.7e-14 54.0 2.7 6.2e-05 23.4 0.2 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001043593.1_29623001_1 - 6.5e-10 39.0 0.0 5.7e-08 32.7 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.4 001043593.1_29623001_1 - 2.7e-06 27.5 0.7 0.012 15.8 0.0 3.8 3 2 0 3 3 3 2 Immunoglobulin domain I-set PF07679.14 001043593.1_29623001_1 - 3.8e-06 26.7 0.1 0.054 13.4 0.0 4.0 3 2 0 3 3 3 1 Immunoglobulin I-set domain TonB_C PF03544.12 001043593.1_29623001_1 - 0.031 14.6 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal Bactofilin PF04519.11 001043593.1_29623001_1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Polymer-forming cytoskeletal Izumo-Ig PF16706.3 001043593.1_29623001_1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain CcmD PF04995.12 001043593.1_29623001_1 - 0.72 9.8 7.7 2.2 8.3 7.7 1.8 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) Ank_2 PF12796.5 001266272.2_29625001_1 - 4.2e-58 193.8 12.8 4.8e-19 68.6 0.4 5.5 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001266272.2_29625001_1 - 3.5e-40 135.8 8.6 9.4e-12 45.1 0.1 8.4 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.28 001266272.2_29625001_1 - 3.6e-40 134.6 14.6 4.3e-06 26.8 0.1 9.4 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.4 001266272.2_29625001_1 - 4.2e-37 121.8 13.4 7.1e-05 22.8 0.0 10.1 9 1 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.4 001266272.2_29625001_1 - 9.4e-35 118.0 13.6 1.1e-07 31.9 0.1 9.1 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Abhydrolase_2 PF02230.14 001266865.1_29624001_2 - 2.6e-41 141.7 0.0 3.2e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.11 001266865.1_29624001_2 - 5.6e-07 29.5 0.1 0.00049 19.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.16 001266865.1_29624001_2 - 7.8e-07 28.7 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.6 001266865.1_29624001_2 - 8.3e-07 28.4 0.4 0.0016 17.6 0.1 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase PF00756.18 001266865.1_29624001_2 - 8.7e-06 25.4 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.5 001266865.1_29624001_2 - 1.2e-05 25.0 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.19 001266865.1_29624001_2 - 7.3e-05 22.2 0.7 0.015 14.7 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.11 001266865.1_29624001_2 - 0.00089 18.8 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.5 001266865.1_29624001_2 - 0.003 18.1 0.0 0.0043 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.18 001266865.1_29624001_2 - 0.0033 17.0 0.3 0.013 15.0 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.18 001266865.1_29624001_2 - 0.026 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.23 001266865.1_29624001_2 - 0.092 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Dimer_Tnp_hAT PF05699.12 001266708.1_29625001_2 - 3.7e-15 55.4 0.1 1.1e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.13 001266708.1_29625001_2 - 3.6e-14 52.4 0.9 3.6e-14 52.4 0.9 1.8 2 0 0 2 2 2 1 BED zinc finger DUF4413 PF14372.4 001266708.1_29625001_2 - 5.5e-05 23.3 0.1 0.0002 21.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DUF659 PF04937.13 001266708.1_29625001_2 - 0.0045 16.7 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) CAF1C_H4-bd PF12265.6 001246374.1_39725001_1 - 1.1e-27 95.9 0.6 4.2e-27 94.1 0.1 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.30 001246374.1_39725001_1 - 4.2e-25 87.4 14.7 6.4e-07 29.8 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001246374.1_39725001_1 - 0.00043 20.4 0.7 0.028 14.6 0.0 3.2 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001246374.1_39725001_1 - 0.0012 18.7 0.6 0.048 13.4 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Glyco_transf_7N PF13733.4 001257832.1_29625001_3 - 5.6e-60 200.7 0.1 8.9e-60 200.0 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.12 001257832.1_29625001_3 - 6.1e-27 93.0 0.4 1.3e-26 91.9 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase STT3 PF02516.12 001243852.1_49825001_3 - 5.8e-163 543.2 40.9 1.3e-158 528.8 37.2 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.4 001243852.1_49825001_3 - 4.1e-06 27.0 14.4 4.1e-06 27.0 14.4 2.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2985 PF11204.6 001243852.1_49825001_3 - 0.23 11.5 4.9 0.51 10.4 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) Syntaphilin PF15290.4 001173111.1_09926001_2 - 1.9e-133 444.8 0.7 2.8e-133 444.3 0.7 1.2 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp Fez1 PF06818.13 001173111.1_09926001_2 - 6.3e-05 23.4 5.9 9.8e-05 22.8 5.9 1.2 1 0 0 1 1 1 1 Fez1 FAM76 PF16046.3 001173111.1_09926001_2 - 0.0046 16.2 8.0 0.0064 15.8 7.6 1.4 1 1 0 1 1 1 1 FAM76 protein PKcGMP_CC PF16808.3 001173111.1_09926001_2 - 0.0086 15.8 6.1 0.0086 15.8 6.1 3.3 3 1 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase WEMBL PF05701.9 001173111.1_09926001_2 - 0.015 13.8 7.8 0.021 13.4 7.8 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Exonuc_VII_L PF02601.13 001173111.1_09926001_2 - 0.062 12.7 2.9 0.091 12.2 2.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HMMR_N PF15905.3 001173111.1_09926001_2 - 0.068 12.5 12.2 0.1 11.9 12.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CALCOCO1 PF07888.9 001173111.1_09926001_2 - 0.091 11.2 11.0 0.14 10.6 11.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.12 001173111.1_09926001_2 - 0.097 12.3 7.4 0.17 11.6 7.4 1.2 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.7 001173111.1_09926001_2 - 0.12 11.3 6.8 0.2 10.5 6.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec2p PF06428.9 001173111.1_09926001_2 - 0.17 11.7 13.1 0.1 12.4 2.6 2.6 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Sec8_exocyst PF04048.12 001173111.1_09926001_2 - 0.17 11.6 6.3 0.65 9.8 0.3 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF342 PF03961.11 001173111.1_09926001_2 - 0.18 10.2 5.0 0.24 9.8 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4681 PF15732.3 001173111.1_09926001_2 - 0.21 11.8 1.7 0.28 11.3 0.3 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4681) DUF16 PF01519.14 001173111.1_09926001_2 - 0.38 11.1 9.4 4 7.8 9.4 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 BST2 PF16716.3 001173111.1_09926001_2 - 0.46 11.0 8.9 1 9.8 8.9 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 HR1 PF02185.14 001173111.1_09926001_2 - 0.54 10.3 9.4 1 9.4 1.1 2.4 2 0 0 2 2 2 0 Hr1 repeat Spc7 PF08317.9 001173111.1_09926001_2 - 0.93 8.2 11.9 1.5 7.5 11.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CC2-LZ PF16516.3 001173111.1_09926001_2 - 1.5 9.1 12.2 1.9 8.7 2.9 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF745 PF05335.11 001173111.1_09926001_2 - 1.6 8.3 6.2 2.4 7.7 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FPP PF05911.9 001173111.1_09926001_2 - 2.6 6.1 17.6 0.016 13.4 9.2 1.4 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Spc42p PF11544.6 001173111.1_09926001_2 - 5.2 7.0 7.2 1.5 8.7 1.2 2.4 2 0 0 2 2 2 0 Spindle pole body component Spc42p TPR_MLP1_2 PF07926.10 001173111.1_09926001_2 - 5.8 6.9 13.2 1.9 8.4 6.4 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.9 001173111.1_09926001_2 - 7.7 6.9 6.3 2.8 8.3 0.8 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ETF PF01012.19 001194707.1_29622001_1 - 4.2e-49 166.8 0.7 5.4e-49 166.4 0.7 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Glyco_transf_7C PF02709.12 001168634.1_39523001_3 - 2.7e-25 87.7 0.2 4.7e-25 86.9 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.4 001168634.1_39523001_3 - 3.8e-23 81.5 0.0 7e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Metallophos PF00149.26 001283126.1_29525001_2 - 3e-35 122.5 0.1 5.4e-35 121.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.10 001283126.1_29525001_2 - 3.9e-32 110.3 1.3 9.7e-32 109.0 1.3 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.26 001283126.1_29525001_2 - 3.1e-14 52.0 12.8 4.1e-08 32.6 1.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.15 001283126.1_29525001_2 - 6.5e-13 47.6 13.0 8e-07 28.6 0.5 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.4 001283126.1_29525001_2 - 2.2e-11 43.1 5.9 2.4e-07 30.2 3.3 3.4 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.4 001283126.1_29525001_2 - 5.5e-09 36.4 1.0 5e-05 23.8 0.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.4 001283126.1_29525001_2 - 3.1e-07 29.9 3.6 0.00037 20.3 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.4 001283126.1_29525001_2 - 3.4e-07 30.2 0.0 0.015 15.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.4 001283126.1_29525001_2 - 4.2e-05 23.9 0.6 0.13 12.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.4 001283126.1_29525001_2 - 4.6e-05 23.8 0.2 0.43 11.4 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.4 001283126.1_29525001_2 - 0.00049 20.2 2.5 0.016 15.4 0.4 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.4 001283126.1_29525001_2 - 0.0045 17.1 3.2 0.032 14.4 1.2 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.4 001283126.1_29525001_2 - 0.0087 16.5 4.2 1.7 9.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.4 001283126.1_29525001_2 - 0.017 15.0 0.7 0.6 10.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.16 001283126.1_29525001_2 - 0.048 13.6 4.1 0.045 13.7 1.7 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.4 001283126.1_29525001_2 - 0.26 11.2 2.1 3.9 7.5 0.1 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.5 001283126.1_29525001_2 - 0.6 10.2 3.5 1.2 9.3 1.9 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-C2H2 PF00096.24 001265918.2_29623001_2 - 7.1e-15 54.4 23.0 6.8e-05 23.0 1.1 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001265918.2_29623001_2 - 5.1e-14 51.8 30.8 1.1e-07 31.8 2.8 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.4 001265918.2_29623001_2 - 1.5e-08 34.6 20.1 0.0018 18.8 2.8 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.3 001265918.2_29623001_2 - 0.0028 18.1 6.2 0.042 14.3 0.3 3.2 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-met PF12874.5 001265918.2_29623001_2 - 0.013 15.7 11.1 0.064 13.5 0.7 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001265918.2_29623001_2 - 0.02 14.7 1.4 0.02 14.7 1.4 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001265918.2_29623001_2 - 0.095 12.9 5.8 0.3 11.3 5.3 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon IBR PF01485.19 001265918.2_29623001_2 - 0.4 10.8 6.3 2.1 8.5 6.3 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-Di19 PF05605.10 001265918.2_29623001_2 - 0.55 10.4 9.2 0.29 11.3 2.7 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Carb_anhydrase PF00194.19 001257903.2_29624001_3 - 2.3e-91 305.7 0.1 2.8e-91 305.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase ETS_PEA3_N PF04621.11 001288818.1_09024001_1 - 6.4e-160 532.6 19.8 9.3e-160 532.0 19.8 1.2 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.20 001288818.1_09024001_1 - 7.9e-38 128.7 0.2 1.3e-37 128.0 0.2 1.3 1 0 0 1 1 1 1 Ets-domain LRR_4 PF12799.5 001266033.1_29625001_1 - 6.6e-11 42.1 10.9 0.0047 17.1 0.0 7.7 2 1 6 8 8 8 5 Leucine Rich repeats (2 copies) F-box PF00646.31 001266033.1_29625001_1 - 3.3e-07 29.9 0.3 3.3e-07 29.9 0.3 3.3 5 0 0 5 5 5 1 F-box domain F-box-like PF12937.5 001266033.1_29625001_1 - 2.3e-05 24.1 2.4 2.3e-05 24.1 2.4 2.3 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.31 001266033.1_29625001_1 - 0.00065 19.7 10.3 13 6.6 0.2 7.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.4 001266033.1_29625001_1 - 0.00091 18.8 5.5 0.22 11.2 0.1 4.6 3 2 1 4 4 4 2 Leucine rich repeat LRR_9 PF14580.4 001266033.1_29625001_1 - 0.0017 17.8 0.9 1.3 8.3 0.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat F-box_4 PF15966.3 001266033.1_29625001_1 - 0.0023 17.7 0.4 0.0086 15.8 0.4 2.0 1 1 0 1 1 1 1 F-box Adeno_E3_CR2 PF02439.13 001266033.1_29625001_1 - 0.013 15.1 1.3 0.025 14.2 1.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRR_6 PF13516.4 001266033.1_29625001_1 - 0.34 10.9 15.0 14 5.9 0.2 6.6 8 0 0 8 8 8 0 Leucine Rich repeat IL8 PF00048.18 001032851.1_29621001_1 - 1.1e-23 83.0 3.0 1.3e-23 82.7 3.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF4725 PF15854.3 001032851.1_29621001_1 - 0.029 14.5 0.3 0.038 14.1 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4725) MGC-24 PF05283.9 001265743.1_29624001_2 - 1.7e-56 190.4 16.5 1.7e-56 190.4 16.5 1.8 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4366 PF14283.4 001265743.1_29624001_2 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Adeno_E3 PF06040.9 001244803.1_49824001_1 - 0.13 12.3 1.4 0.23 11.5 1.4 1.2 1 0 0 1 1 1 0 Adenovirus E3 protein HVSL PF09749.7 001244803.1_49824001_3 - 9.2e-63 211.8 0.0 1.2e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein DKCLD PF08068.10 001168809.1_40424001_1 - 3.4e-31 107.0 0.1 2.2e-30 104.4 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.16 001168809.1_40424001_1 - 7.6e-22 78.1 0.1 1.4e-18 67.6 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.3 001168809.1_40424001_1 - 1.1e-21 76.6 0.6 2e-21 75.7 0.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.18 001168809.1_40424001_1 - 2.1e-18 65.9 1.8 5.3e-18 64.6 1.8 1.7 1 0 0 1 1 1 1 PUA domain Ets PF00178.20 001285769.1_09025001_2 - 8e-37 125.5 1.2 1.5e-36 124.6 1.2 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.14 001285769.1_09025001_2 - 8.6e-34 115.2 0.1 1.6e-33 114.4 0.1 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ion_trans_2 PF07885.14 001172762.1_09922001_1 - 1.1e-25 89.3 1.9 4.2e-13 48.9 0.1 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.29 001172762.1_09922001_1 - 0.00099 18.3 0.0 0.048 12.8 0.0 2.2 2 0 0 2 2 2 2 Ion transport protein OLF PF02191.14 213986.1_49825001_2 - 1e-84 283.8 0.4 1.4e-84 283.4 0.4 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain IncA PF04156.12 213986.1_49825001_2 - 1.3e-06 28.2 16.3 3.9e-06 26.7 12.1 2.2 2 0 0 2 2 2 1 IncA protein ADIP PF11559.6 213986.1_49825001_2 - 0.0088 16.0 17.9 0.014 15.3 16.2 1.9 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.9 213986.1_49825001_2 - 0.0099 15.9 16.0 0.019 15.0 16.0 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) BRE1 PF08647.9 213986.1_49825001_2 - 0.012 15.6 8.7 0.012 15.6 8.7 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.9 213986.1_49825001_2 - 0.015 14.1 14.1 0.025 13.4 14.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.10 213986.1_49825001_2 - 0.017 14.4 15.2 0.03 13.6 15.2 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 KASH_CCD PF14662.4 213986.1_49825001_2 - 0.033 13.9 11.0 0.063 13.0 11.0 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FPP PF05911.9 213986.1_49825001_2 - 0.19 9.8 11.9 0.29 9.2 11.9 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil GAS PF13851.4 213986.1_49825001_2 - 0.24 10.6 12.3 0.24 10.6 7.6 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.16 213986.1_49825001_2 - 0.26 11.4 8.1 0.56 10.3 6.8 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper Macoilin PF09726.7 213986.1_49825001_2 - 0.26 9.7 7.0 0.36 9.2 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Exonuc_VII_L PF02601.13 213986.1_49825001_2 - 0.29 10.5 7.1 0.47 9.8 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.10 213986.1_49825001_2 - 0.34 10.8 20.3 0.86 9.5 6.5 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.11 213986.1_49825001_2 - 0.49 8.8 3.4 0.73 8.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fmp27_WPPW PF10359.7 213986.1_49825001_2 - 0.61 8.7 5.1 0.95 8.1 5.1 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PspA_IM30 PF04012.10 213986.1_49825001_2 - 0.68 9.3 13.2 0.23 10.9 7.4 2.1 2 0 0 2 2 2 0 PspA/IM30 family Leu_zip PF15294.4 213986.1_49825001_2 - 0.75 9.1 11.0 1.2 8.4 10.9 1.4 1 1 0 1 1 1 0 Leucine zipper DivIC PF04977.13 213986.1_49825001_2 - 0.95 9.1 17.4 0.12 12.0 6.3 3.1 1 1 2 3 3 3 0 Septum formation initiator Cep57_MT_bd PF06657.11 213986.1_49825001_2 - 1.1 9.6 11.2 0.18 12.2 7.0 1.8 2 0 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 DUF972 PF06156.11 213986.1_49825001_2 - 1.2 9.7 9.8 0.19 12.2 5.6 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.17 213986.1_49825001_2 - 1.4 6.5 3.8 2 6.1 3.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.6 213986.1_49825001_2 - 1.5 7.9 17.6 0.16 11.1 10.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.11 213986.1_49825001_2 - 1.7 7.6 5.5 8.6 5.4 3.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF2203 PF09969.7 213986.1_49825001_2 - 2.1 8.9 5.1 0.85 10.2 2.0 1.8 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) Uso1_p115_C PF04871.11 213986.1_49825001_2 - 2.3 8.4 16.2 0.29 11.4 9.7 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HAUS-augmin3 PF14932.4 213986.1_49825001_2 - 3 7.1 16.6 0.77 9.1 12.5 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 NYD-SP28_assoc PF14775.4 213986.1_49825001_2 - 3.3 7.8 11.4 2.3 8.3 2.7 2.9 1 1 1 2 2 2 0 Sperm tail C-terminal domain YlqD PF11068.6 213986.1_49825001_2 - 3.7 7.8 7.9 1.3 9.2 4.2 2.1 2 0 0 2 2 2 0 YlqD protein DUF4407 PF14362.4 213986.1_49825001_2 - 3.7 6.7 9.5 5.5 6.1 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mnd1 PF03962.13 213986.1_49825001_2 - 4 7.1 11.9 1.3 8.8 6.3 2.1 2 0 0 2 2 2 0 Mnd1 family TBPIP PF07106.11 213986.1_49825001_2 - 4.5 6.9 10.3 1.3 8.7 6.4 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pkinase PF00069.23 001260877.1_29626001_3 - 1.3e-71 240.9 0.3 1.6e-71 240.6 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001260877.1_29626001_3 - 6.7e-20 71.3 0.0 9.4e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001260877.1_29626001_3 - 4.2e-07 30.0 0.1 1.9e-05 24.6 0.1 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.12 001260877.1_29626001_3 - 0.0012 18.1 0.1 0.002 17.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.18 001260877.1_29626001_3 - 0.028 13.9 0.3 0.055 12.9 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.4 001260877.1_29626001_3 - 0.058 12.6 0.2 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like ABC1 PF03109.14 001260877.1_29626001_3 - 0.19 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Renin_r PF07850.12 001257625.1_29624001_3 - 3e-36 123.9 1.3 4.8e-36 123.2 1.3 1.3 1 0 0 1 1 1 1 Renin receptor-like protein Seipin PF06775.12 001132443.2_43524001_1 - 1.3e-58 198.2 0.9 1.8e-58 197.8 0.9 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) UPF0239 PF06783.9 001266836.1_29623001_3 - 1.3e-32 111.7 0.0 1.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) CD20 PF04103.13 001257245.1_08023001_1 - 2.3e-47 160.8 6.6 3.3e-47 160.3 6.6 1.2 1 0 0 1 1 1 1 CD20-like family CM2 PF03021.12 001257245.1_08023001_1 - 0.036 13.8 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Influenza C virus M2 protein UQ_con PF00179.24 001257571.1_29623001_2 - 3.6e-46 156.2 0.0 5.2e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.4 001257571.1_29623001_2 - 0.028 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.20 001257571.1_29623001_2 - 0.037 14.2 0.1 0.069 13.3 0.1 1.4 1 0 0 1 1 1 0 RWD domain HCO3_cotransp PF00955.19 001258188.1_29629001_2 - 4.6e-247 820.8 10.7 5.7e-247 820.4 10.7 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.11 001258188.1_29629001_2 - 2.2e-106 355.5 0.0 3.3e-106 354.9 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Mu-transpos_C PF09299.9 001258188.1_29629001_2 - 0.046 13.5 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Mu transposase, C-terminal SNF PF00209.16 001134952.1_29625001_3 - 5.9e-248 823.6 36.1 6.9e-248 823.4 36.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Zip PF02535.20 001260918.1_29627001_3 - 1.5e-103 346.4 24.1 1.5e-103 346.4 24.1 4.3 2 2 0 2 2 2 1 ZIP Zinc transporter KKLCAg1 PF15204.4 001260918.1_29627001_3 - 0.097 12.6 0.1 4 7.4 0.0 2.5 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 MFS_1 PF07690.14 001257704.1_29626001_2 - 1.6e-38 132.4 24.2 2.6e-34 118.6 24.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.8 001257704.1_29626001_2 - 0.31 10.6 5.1 0.13 11.9 0.6 2.4 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) PHD_4 PF16866.3 001265720.1_29625001_1 - 1.7e-25 88.8 6.4 1.7e-25 88.8 6.4 2.0 2 0 0 2 2 1 1 PHD-finger zf-CXXC PF02008.18 001265720.1_29625001_1 - 1.2e-13 50.7 21.7 1.2e-13 50.7 21.7 2.8 3 0 0 3 3 2 1 CXXC zinc finger domain F-box PF00646.31 001265720.1_29625001_1 - 2.3e-09 36.8 2.5 2.3e-09 36.8 2.5 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.5 001265720.1_29625001_1 - 4.1e-06 26.4 4.7 4.1e-06 26.4 4.7 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.5 001265720.1_29625001_1 - 8.1e-05 22.7 0.8 0.48 10.8 0.1 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.4 001265720.1_29625001_1 - 9.2e-05 22.1 1.6 14 5.9 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich repeat PHD PF00628.27 001265720.1_29625001_1 - 0.0018 18.0 5.6 0.0018 18.0 5.6 2.6 2 0 0 2 2 1 1 PHD-finger LRR_8 PF13855.4 001265720.1_29625001_1 - 0.0033 17.0 2.5 4.4 7.0 0.0 3.2 3 0 0 3 3 3 2 Leucine rich repeat C1_1 PF00130.20 001265720.1_29625001_1 - 0.028 14.2 0.2 0.028 14.2 0.2 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RbpA PF13397.4 001265720.1_29625001_1 - 0.04 14.4 1.0 0.18 12.3 0.2 2.1 2 0 0 2 2 2 0 RNA polymerase-binding protein LRR_1 PF00560.31 001265720.1_29625001_1 - 3.7 8.3 11.8 19 6.1 0.1 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat zf-4CXXC_R1 PF10497.7 001265720.1_29625001_1 - 8.7 6.5 15.9 23 5.2 13.4 2.5 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PRKCSH_1 PF13015.4 001204748.1_29623001_2 - 2.3e-09 37.0 0.0 4.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.11 001204748.1_29623001_2 - 9.7e-08 32.8 1.7 9.7e-08 32.8 1.7 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DPM3 PF08285.9 001204748.1_29623001_2 - 0.033 14.2 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) AltA1 PF16541.3 001204748.1_29623001_2 - 0.084 13.6 0.4 0.19 12.4 0.4 1.6 1 0 0 1 1 1 0 Alternaria alternata allergen 1 DMAP_binding PF06464.9 001204748.1_29623001_2 - 0.092 13.4 0.1 0.092 13.4 0.1 2.1 3 0 0 3 3 3 0 DMAP1-binding Domain TRP_2 PF08344.9 001145751.1_49825001_1 - 4.4e-25 87.5 2.2 9.5e-25 86.5 2.2 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.29 001145751.1_49825001_1 - 1e-16 60.8 12.9 1.9e-16 59.9 12.9 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.5 001145751.1_49825001_1 - 1.6e-06 28.5 0.1 5.5e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001145751.1_49825001_1 - 0.00023 21.5 0.0 0.14 12.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001145751.1_49825001_1 - 0.063 13.7 1.1 1.1e+02 3.8 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat DUF2157 PF09925.7 001145751.1_49825001_1 - 4.2 7.0 6.2 2.7 7.7 3.7 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) KCNQ_channel PF03520.12 001265828.1_29629001_2 - 2.9e-94 314.1 1.6 5.2e-94 313.3 1.6 1.4 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.29 001265828.1_29629001_2 - 1.2e-25 90.0 11.7 1.8e-25 89.5 11.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.14 001265828.1_29629001_2 - 3.2e-14 52.5 5.3 7.8e-14 51.3 5.3 1.7 1 0 0 1 1 1 1 Ion channel zf-C2H2 PF00096.24 001285215.1_29524001_3 - 1.9e-20 72.0 42.8 7.4e-06 26.0 1.3 6.1 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001285215.1_29524001_3 - 8.3e-19 66.5 31.4 0.00013 22.3 1.1 6.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001285215.1_29524001_3 - 1.7e-14 53.3 41.5 1.6e-07 31.3 0.5 6.6 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.6 001285215.1_29524001_3 - 3.7e-12 46.1 21.0 0.0011 19.0 0.1 5.9 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001285215.1_29524001_3 - 2.9e-10 39.7 24.7 0.0074 16.1 0.7 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.5 001285215.1_29524001_3 - 5.6e-07 29.6 24.3 0.012 15.8 0.7 5.9 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-Di19 PF05605.10 001285215.1_29524001_3 - 1.5e-06 28.3 17.2 0.014 15.5 3.0 3.8 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.13 001285215.1_29524001_3 - 0.0016 18.3 24.7 0.76 9.8 0.2 5.7 2 1 3 5 5 5 2 BED zinc finger zinc_ribbon_15 PF17032.3 001285215.1_29524001_3 - 0.024 15.3 1.2 0.024 15.3 1.2 2.9 2 1 0 2 2 1 0 zinc-ribbon family zf-C2HC_2 PF13913.4 001285215.1_29524001_3 - 0.3 10.9 24.4 2.6 7.9 1.1 5.9 6 0 0 6 6 6 0 zinc-finger of a C2HC-type DUF4764 PF15961.3 001285215.1_29524001_3 - 0.42 9.1 6.7 0.32 9.5 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) Zn-ribbon_8 PF09723.8 001285215.1_29524001_3 - 2.4 8.2 20.5 1.4 8.9 2.1 4.2 3 1 1 4 4 4 0 Zinc ribbon domain zf-AN1 PF01428.14 001285215.1_29524001_3 - 3.8 7.6 22.3 22 5.2 1.9 5.5 5 0 0 5 5 5 0 AN1-like Zinc finger Zn_Tnp_IS1595 PF12760.5 001285215.1_29524001_3 - 6.1 6.8 22.3 0.14 12.0 4.9 4.1 3 1 1 4 4 4 0 Transposase zinc-ribbon domain LRR_8 PF13855.4 001261503.1_29625001_2 - 1.1e-21 76.1 35.2 2.9e-12 46.0 9.1 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.5 001261503.1_29625001_2 - 6.5e-09 35.8 25.1 0.00091 19.4 3.7 3.6 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.16 001261503.1_29625001_2 - 1.5e-08 34.0 5.2 7.5e-08 31.7 5.2 2.4 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.4 001261503.1_29625001_2 - 1.3e-05 25.1 0.0 5.8e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001261503.1_29625001_2 - 0.2 11.0 5.2 0.4 10.0 2.6 1.9 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.31 001261503.1_29625001_2 - 0.83 10.2 23.8 0.93 10.1 0.6 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat Bromodomain PF00439.23 001261702.1_29629001_2 - 2.4e-10 40.2 0.0 5.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.15 001261702.1_29629001_2 - 9e-10 38.8 0.4 9e-10 38.8 0.4 3.1 2 1 0 2 2 2 1 PWWP domain DUF1002 PF06207.9 001261702.1_29629001_2 - 0.16 11.4 1.3 0.31 10.4 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Spore_III_AB PF09548.8 001261702.1_29629001_2 - 2.4 8.1 6.5 1.6 8.7 4.4 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) GST_N_3 PF13417.4 001257531.1_29624001_1 - 1.8e-10 40.9 0.0 3.5e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001257531.1_29624001_1 - 8.2e-08 32.4 0.0 3e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001257531.1_29624001_1 - 2.5e-07 30.8 0.0 5.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001257531.1_29624001_1 - 2.7e-06 27.1 0.0 7.3e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001257531.1_29624001_1 - 1.8e-05 24.8 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001257531.1_29624001_1 - 0.0031 17.5 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Nsp1 PF11501.6 001257531.1_29624001_1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Non structural protein Nsp1 Asp PF00026.21 001260928.1_29629001_1 - 8.1e-44 150.2 0.0 1.1e-43 149.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.4 001260928.1_29629001_1 - 2.9e-10 40.0 0.0 4.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.4 001260928.1_29629001_1 - 3.2e-05 24.1 0.0 0.015 15.5 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal adh_short PF00106.23 001047132.1_29622001_1 - 5.6e-38 130.2 0.0 7.7e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001047132.1_29622001_1 - 1.7e-26 93.1 0.0 2.3e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001047132.1_29622001_1 - 1.2e-08 35.0 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001047132.1_29622001_1 - 0.0047 16.3 0.0 0.018 14.4 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.8 001047132.1_29622001_1 - 0.068 12.4 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.6 001047132.1_29622001_1 - 0.24 11.0 1.0 0.65 9.7 0.1 2.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyrid_oxidase_2 PF13883.4 001194358.1_29622001_1 - 1.6e-50 171.3 0.0 2.2e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.18 001194358.1_29622001_1 - 0.0054 16.8 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sec1 PF00995.21 001244994.1_49825001_3 - 4.7e-132 441.9 3.8 5.7e-132 441.7 3.8 1.1 1 0 0 1 1 1 1 Sec1 family Zip PF02535.20 001285563.1_09023001_3 - 7.4e-48 163.3 16.7 2e-47 161.9 16.7 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter IF2_N PF04760.13 001285563.1_09023001_3 - 0.11 12.2 0.2 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region UQ_con PF00179.24 001260974.1_29623001_3 - 2.3e-30 104.9 0.0 3.1e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme WD40 PF00400.30 001265894.1_29626001_1 - 3.3e-41 138.4 25.2 4.7e-08 33.4 0.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001265894.1_29626001_1 - 1.3e-14 54.1 0.0 0.0011 19.1 0.0 5.5 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.3 001265894.1_29626001_1 - 0.00016 20.9 0.0 0.0012 18.2 0.0 2.0 1 1 1 2 2 2 2 WD40-like domain eIF2A PF08662.9 001265894.1_29626001_1 - 0.0005 19.9 0.0 0.73 9.5 0.0 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A CALM_bind PF16025.3 001265894.1_29626001_1 - 0.024 14.9 0.2 0.041 14.2 0.2 1.3 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Myc-LZ PF02344.13 001265894.1_29626001_1 - 0.08 12.9 1.0 0.17 11.9 1.0 1.5 1 0 0 1 1 1 0 Myc leucine zipper domain Serpin PF00079.18 001168912.1_40422001_1 - 2.1e-62 211.4 0.0 2.4e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pkinase PF00069.23 001266640.1_29628001_1 - 8.2e-77 258.0 0.0 1.4e-76 257.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001266640.1_29628001_1 - 1.1e-35 123.0 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.27 001266640.1_29628001_1 - 2.1e-14 53.8 0.1 4.9e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.22 001266640.1_29628001_1 - 6.6e-09 36.2 2.6 1.2e-08 35.3 2.6 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.4 001266640.1_29628001_1 - 7e-08 32.0 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Requiem_N PF14051.4 001285611.1_09023001_1 - 1.1e-36 124.7 1.3 2e-36 123.8 1.3 1.5 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.27 001285611.1_09023001_1 - 2.5e-20 71.9 23.9 2.6e-11 43.1 8.0 3.3 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.3 001285611.1_09023001_1 - 0.0058 16.6 8.0 0.0058 16.6 8.0 3.5 2 1 1 3 3 3 1 PHD-finger zf-C2H2_4 PF13894.4 001285611.1_09023001_1 - 0.022 15.5 0.7 0.022 15.5 0.7 4.9 5 1 1 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.24 001285611.1_09023001_1 - 0.084 13.2 1.2 0.084 13.2 1.2 4.7 5 0 0 5 5 5 0 Zinc finger, C2H2 type Zf_RING PF16744.3 001285611.1_09023001_1 - 2.6 8.1 24.2 4.2 7.4 6.8 4.8 2 1 2 4 4 4 0 KIAA1045 RING finger C1_1 PF00130.20 001285611.1_09023001_1 - 6.7 6.5 24.4 0.5 10.2 0.6 4.4 3 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lar_restr_allev PF14354.4 001285611.1_09023001_1 - 8.5 6.7 24.6 36 4.7 12.9 4.2 3 1 1 4 4 4 0 Restriction alleviation protein Lar Ank_2 PF12796.5 001173055.1_09926001_3 - 1.7e-39 134.1 1.9 6.4e-11 42.6 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001173055.1_09926001_3 - 1.2e-33 114.4 0.3 4.5e-08 33.1 0.0 5.1 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.4 001173055.1_09926001_3 - 1.3e-31 108.4 0.0 6.3e-08 32.9 0.0 6.1 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.28 001173055.1_09926001_3 - 1.7e-28 97.7 0.6 6e-05 23.2 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ribonuc_2-5A PF06479.10 001173055.1_09926001_3 - 2.4e-28 98.7 2.3 2.4e-28 98.7 2.3 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A Ank_3 PF13606.4 001173055.1_09926001_3 - 6e-26 87.5 0.6 8.1e-05 22.6 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Pkinase PF00069.23 001173055.1_09926001_3 - 2.2e-21 76.2 0.3 1.1e-18 67.5 0.1 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.15 001173055.1_09926001_3 - 1.3e-12 47.5 0.0 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001173055.1_09926001_3 - 6.6e-05 22.2 0.1 0.00015 21.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.4 001173055.1_09926001_3 - 0.009 15.2 0.0 0.044 13.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Enolase_C PF00113.20 001195611.1_29624001_2 - 2.1e-156 519.5 0.0 2.9e-156 519.0 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.14 001195611.1_29624001_2 - 4.3e-61 204.7 0.1 6.8e-61 204.1 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.4 001195611.1_29624001_2 - 6.4e-08 32.4 0.0 9.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.9 001195611.1_29624001_2 - 0.003 16.6 0.4 0.0061 15.6 0.4 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus UCH PF00443.27 001266739.1_29626001_3 - 1.3e-50 172.1 1.8 1.7e-50 171.7 1.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 001266739.1_29626001_3 - 5.9e-14 52.3 9.3 1.1e-13 51.3 9.3 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.21 001266739.1_29626001_3 - 0.00097 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family CBF PF03914.15 001144115.1_49825001_3 - 4.4e-31 108.0 0.6 1.8e-30 106.0 0.2 2.3 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.9 001144115.1_49825001_3 - 2e-29 101.7 1.3 2e-29 101.7 1.3 3.1 3 0 0 3 3 3 1 Nucleolar complex-associated protein DUF2732 PF10809.6 001144115.1_49825001_3 - 0.0034 17.1 0.1 0.016 14.9 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2732) DsrD PF08679.9 001144115.1_49825001_3 - 0.042 14.0 2.2 0.081 13.1 0.1 2.6 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Pkinase_Tyr PF07714.15 001266690.1_29627001_1 - 7.5e-32 110.5 0.1 1e-31 110.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001266690.1_29627001_1 - 2.5e-30 105.6 0.0 3.5e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.10 001266690.1_29627001_1 - 3.2e-15 55.2 0.1 6e-15 54.3 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif TPK_B1_binding PF04265.12 001260926.1_29624001_1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain WD40 PF00400.30 001260926.1_29624001_3 - 4.5e-18 65.2 10.2 0.00022 21.8 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001260926.1_29624001_3 - 0.0011 19.1 0.0 15 5.9 0.0 4.6 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain S-AdoMet_synt_C PF02773.14 001195289.1_29626001_2 - 1.2e-66 222.8 0.0 1.9e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.14 001195289.1_29626001_2 - 1.7e-45 153.9 0.0 3.1e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.18 001195289.1_29626001_2 - 1.1e-43 147.7 0.2 1.9e-43 147.0 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.17 001195289.1_29626001_2 - 0.055 12.1 0.4 0.22 10.2 0.2 1.8 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Mito_carr PF00153.25 001265644.1_29623001_1 - 1.8e-60 200.7 1.1 1.8e-22 78.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PTPA PF03095.13 001169081.1_40423001_1 - 4.6e-123 410.3 0.0 5.6e-123 410.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein 7tm_1 PF00001.19 001193683.1_29623001_1 - 8.4e-73 244.8 7.4 1.3e-72 244.2 7.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001193683.1_29623001_1 - 5.2e-09 35.7 13.6 2.8e-08 33.3 13.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.7 001193683.1_29623001_1 - 2.6e-07 30.1 12.0 0.0013 18.1 7.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.7 001193683.1_29623001_1 - 8.1e-05 21.9 10.8 8.1e-05 21.9 10.8 2.4 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2208 PF09973.7 001193683.1_29623001_1 - 0.045 13.2 8.0 0.52 9.8 0.1 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) Glycoprotein_G PF00802.17 001193683.1_29623001_1 - 1.6 7.9 4.3 0.28 10.4 0.6 1.5 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G Mito_carr PF00153.25 001257587.1_29624001_2 - 6.4e-50 166.9 4.9 7.3e-19 67.4 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein PEN-2 PF10251.7 001194826.1_29622001_1 - 1e-38 131.4 5.4 1.4e-38 131.0 5.4 1.2 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase PRA1 PF03208.17 001260923.1_29622001_1 - 3.5e-38 130.3 1.5 4.4e-38 130.0 1.5 1.1 1 0 0 1 1 1 1 PRA1 family protein Gelsolin PF00626.20 001266939.1_29623001_3 - 8.8e-58 192.0 0.0 7.8e-20 70.4 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat FHA PF00498.24 001287643.1_29524001_3 - 1.2e-13 51.0 0.0 2.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.4 001287643.1_29524001_3 - 3.9e-10 39.3 8.4 9.9e-10 38.0 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001287643.1_29524001_3 - 3.7e-09 36.2 11.5 3.7e-09 36.2 11.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001287643.1_29524001_3 - 4.3e-09 35.9 8.9 1.2e-08 34.5 8.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001287643.1_29524001_3 - 8e-08 32.3 10.2 8e-08 32.3 10.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.4 001287643.1_29524001_3 - 6.6e-07 29.3 11.5 6.6e-07 29.3 11.5 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.4 001287643.1_29524001_3 - 2.4e-06 27.3 3.2 3.6e-06 26.8 1.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001287643.1_29524001_3 - 2.6e-06 27.1 6.9 2.6e-06 27.1 6.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.4 001287643.1_29524001_3 - 5.8e-06 25.9 6.7 1.4e-05 24.7 6.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.5 001287643.1_29524001_3 - 1.7e-05 24.9 8.7 8.5e-05 22.6 8.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain Yop-YscD_cpl PF16697.3 001287643.1_29524001_3 - 0.0007 19.7 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.5 001287643.1_29524001_3 - 0.0052 16.7 1.9 0.014 15.3 1.9 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.4 001287643.1_29524001_3 - 0.0059 16.3 4.6 0.013 15.2 4.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.3 001287643.1_29524001_3 - 0.016 15.2 6.7 0.036 14.1 6.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.4 001287643.1_29524001_3 - 0.034 13.7 4.3 0.11 12.2 4.3 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Golgin_A5 PF09787.7 001287643.1_29524001_3 - 0.07 12.4 27.5 0.13 11.5 27.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_30_3 PF08010.9 001287643.1_29524001_3 - 1.3 8.7 7.0 1.3 8.7 5.9 1.5 1 1 0 1 1 1 0 Bacteriophage protein GP30.3 DUF4665 PF15679.3 001287643.1_29524001_3 - 3.2 8.3 20.1 0.053 14.0 8.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) DUF4407 PF14362.4 001287643.1_29524001_3 - 5.6 6.1 25.4 10 5.2 23.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) G-gamma PF00631.20 001204970.1_29623001_1 - 1.4e-14 53.7 0.0 2.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 GGL domain Glyco_transf_29 PF00777.16 001246225.1_32323001_1 - 1.1e-35 123.2 0.0 1.8e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G-gamma PF00631.20 001266578.1_29621001_2 - 9e-18 63.9 0.0 1.1e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain Myc-LZ PF02344.13 001266578.1_29621001_2 - 0.32 11.0 1.7 0.53 10.3 1.7 1.3 1 0 0 1 1 1 0 Myc leucine zipper domain MARVEL PF01284.21 001266122.1_29627001_3 - 2.4e-11 43.7 9.5 5.6e-11 42.5 9.5 1.7 1 0 0 1 1 1 1 Membrane-associating domain G-alpha PF00503.18 001173084.1_09925001_2 - 1.3e-120 402.7 1.6 1.7e-120 402.3 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001173084.1_09925001_2 - 4.4e-14 52.2 0.6 2.5e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001173084.1_09925001_2 - 0.0017 17.6 0.5 0.51 9.5 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.11 001173084.1_09925001_2 - 0.015 15.4 0.0 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsJ PF01728.17 001266892.1_29622001_3 - 1.8e-51 174.6 0.0 2.2e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.4 001266892.1_29622001_3 - 0.0026 17.5 0.0 0.0063 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ferric_reduct PF01794.17 001168988.1_40423001_1 - 2.6e-14 53.3 13.1 1.1e-13 51.3 5.1 2.5 1 1 1 2 2 2 2 Ferric reductase like transmembrane component 7tm_4 PF13853.4 001000492.1_45722001_1 - 3.6e-59 200.6 15.8 4.3e-59 200.4 15.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000492.1_45722001_1 - 6.6e-27 94.3 16.5 2e-26 92.7 16.5 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000492.1_45722001_1 - 1.5e-08 34.2 13.8 1.5e-08 34.2 13.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001000492.1_45722001_1 - 0.0012 18.1 13.0 0.0022 17.2 12.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Pkinase PF00069.23 001105546.2_29625001_3 - 8.8e-52 175.9 0.0 1.2e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001105546.2_29625001_3 - 1.1e-23 83.7 0.0 1.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SCAN PF02023.15 001105764.1_45725001_1 - 2.8e-39 132.7 1.0 6.1e-39 131.6 1.0 1.6 1 0 0 1 1 1 1 SCAN domain zf-H2C2_2 PF13465.4 001105764.1_45725001_1 - 2.6e-35 119.2 28.8 1e-09 38.3 2.0 6.6 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.24 001105764.1_45725001_1 - 1.5e-24 84.9 35.2 1e-05 25.5 1.2 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001105764.1_45725001_1 - 4.2e-12 45.7 38.3 0.0038 17.8 1.2 7.1 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001105764.1_45725001_1 - 0.00042 20.4 20.4 0.0077 16.4 0.1 5.9 6 1 1 7 7 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001105764.1_45725001_1 - 0.0007 19.8 18.8 0.64 10.3 0.7 5.2 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001105764.1_45725001_1 - 0.014 15.2 43.6 0.019 14.8 0.5 6.4 7 0 0 7 7 6 0 C2H2-type zinc finger C1_4 PF07975.10 001105764.1_45725001_1 - 0.015 15.4 10.3 1.5 9.0 0.3 4.2 2 1 1 3 3 3 0 TFIIH C1-like domain zf-LYAR PF08790.9 001105764.1_45725001_1 - 0.21 11.4 20.2 0.79 9.6 0.2 5.4 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger C1_1 PF00130.20 001105764.1_45725001_1 - 0.34 10.7 20.2 2 8.3 1.3 5.8 3 1 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.17 001105764.1_45725001_1 - 2 8.3 11.2 6.9 6.6 0.6 3.4 1 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FdhE PF04216.10 001105764.1_45725001_1 - 2.1 8.0 6.5 7.7 6.1 6.5 2.0 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF2321 PF10083.7 001105764.1_45725001_1 - 2.3 7.7 4.7 13 5.2 0.1 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF3268 PF11672.6 001105764.1_45725001_1 - 3.3 7.9 4.8 7.1 6.9 0.2 2.7 1 1 1 3 3 3 0 zinc-finger-containing domain zinc_ribbon_15 PF17032.3 001105764.1_45725001_1 - 7.5 7.2 12.5 14 6.4 0.8 3.9 2 1 2 4 4 4 0 zinc-ribbon family Prok-RING_1 PF14446.4 001105764.1_45725001_1 - 8.7 6.2 11.6 5.3 6.9 0.8 4.7 3 1 1 4 4 3 0 Prokaryotic RING finger family 1 DUF2072 PF09845.7 001105764.1_45725001_1 - 9.7 6.3 14.3 14 5.8 2.3 4.2 4 1 0 4 4 4 0 Zn-ribbon containing protein Trypsin PF00089.24 001105772.1_45723001_2 - 2.1e-61 207.4 0.0 2.6e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001105772.1_45723001_2 - 0.00043 20.5 0.1 0.00083 19.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001105772.1_45723001_2 - 0.0013 19.5 0.0 0.0028 18.4 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain PIN_4 PF13638.4 001105960.1_45728001_3 - 9e-28 97.1 0.1 9e-28 97.1 0.1 3.4 3 1 0 3 3 3 1 PIN domain WD40 PF00400.30 001100968.2_45725001_2 - 2.8e-31 106.9 16.9 0.0024 18.5 0.1 11.4 11 1 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001100968.2_45725001_2 - 2.8e-06 27.4 1.0 0.37 11.0 0.0 5.5 4 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain zf-H2C2_2 PF13465.4 001135897.1_45724001_1 - 4.5e-37 124.7 46.9 8.3e-08 32.2 1.1 7.8 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.24 001135897.1_45724001_1 - 6.5e-29 98.6 49.6 1.9e-06 27.9 0.6 8.4 8 0 0 8 8 8 7 Zinc finger, C2H2 type KRAB PF01352.25 001135897.1_45724001_1 - 5.8e-21 73.8 0.3 1e-20 73.0 0.3 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001135897.1_45724001_1 - 5.4e-15 54.6 56.7 0.001 19.6 1.8 8.1 8 0 0 8 8 7 7 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001135897.1_45724001_1 - 0.0018 18.4 22.0 0.096 12.9 6.4 3.9 1 1 3 4 4 4 2 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.8 001135897.1_45724001_1 - 0.009 16.0 33.1 0.066 13.2 1.9 5.5 5 1 2 7 7 7 5 Zinc ribbon domain BolA PF01722.16 001135897.1_45724001_1 - 0.016 15.3 3.8 0.45 10.7 0.2 3.3 3 1 1 4 4 4 0 BolA-like protein zf-C2H2_6 PF13912.4 001135897.1_45724001_1 - 0.025 14.4 33.6 0.14 12.0 0.7 7.5 7 0 0 7 7 7 0 C2H2-type zinc finger OGG_N PF07934.10 001135897.1_45724001_1 - 0.11 12.5 1.1 0.25 11.3 0.2 2.0 2 0 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain zf-C2H2_jaz PF12171.6 001135897.1_45724001_1 - 0.21 11.8 22.5 0.11 12.7 0.7 5.7 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.6 001135897.1_45724001_1 - 0.42 10.8 16.8 1.3 9.2 1.3 3.9 2 1 1 4 4 4 0 zinc-finger-containing domain XPA_N PF01286.16 001135897.1_45724001_1 - 0.82 9.6 24.7 13 5.8 0.5 6.6 6 0 0 6 6 6 0 XPA protein N-terminal CpXC PF14353.4 001135897.1_45724001_1 - 1.2 9.0 21.2 7.5 6.5 0.1 6.1 1 1 6 7 7 7 0 CpXC protein Gly_acyl_tr_N PF06021.9 001126278.1_45724001_2 - 3e-87 291.8 0.3 4.1e-87 291.4 0.3 1.2 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Gly_acyl_tr_C PF08444.8 001126278.1_45724001_2 - 7.4e-44 147.8 0.3 1.4e-43 146.9 0.3 1.5 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region RhoGAP PF00620.25 001106158.1_45729001_1 - 4.3e-36 123.9 0.0 2.7e-35 121.3 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain Drc1-Sld2 PF11719.6 001106158.1_45729001_1 - 3e-06 26.9 34.4 0.00029 20.4 4.2 3.4 3 0 0 3 3 3 2 DNA replication and checkpoint protein MazG PF03819.15 001106158.1_45729001_1 - 0.0032 17.5 0.6 0.0032 17.5 0.6 1.9 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain PilJ PF13675.4 001106158.1_45729001_1 - 0.4 10.6 3.3 6.9 6.6 0.7 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term EMP24_GP25L PF01105.22 001106183.1_45722001_3 - 2.7e-30 105.5 0.9 3.3e-30 105.2 0.9 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4516 PF14990.4 001135566.1_45721001_2 - 1.3e-24 85.5 1.7 1.9e-24 85.0 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) OAS1_C PF10421.7 001009680.1_45724001_2 - 3.6e-82 274.2 0.0 5e-82 273.8 0.0 1.2 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.21 001009680.1_45724001_2 - 4.2e-11 42.9 0.0 7.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PDR_CDR PF06422.10 001009680.1_45724001_2 - 0.17 11.7 1.4 0.36 10.6 1.4 1.5 1 0 0 1 1 1 0 CDR ABC transporter DUF4551 PF15087.4 001127567.1_45724001_2 - 4.6e-222 739.1 4.4 5.3e-222 738.9 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) Ly49 PF08391.8 001009718.1_45723001_2 - 1e-53 180.6 5.9 1.8e-53 179.8 5.9 1.4 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region Lectin_C PF00059.19 001009718.1_45723001_2 - 1.8e-13 51.0 4.0 3.9e-13 49.9 4.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain OLF PF02191.14 001106287.1_45724001_3 - 5e-72 242.3 1.9 6.7e-72 241.9 1.9 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain CEP63 PF17045.3 001106287.1_45724001_3 - 1.3 8.7 7.5 0.063 13.0 1.4 1.7 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa CD20 PF04103.13 001106339.1_45722001_1 - 3.7e-21 75.7 27.4 5.8e-19 68.6 17.7 2.1 1 1 1 2 2 2 2 CD20-like family WD40 PF00400.30 001127559.2_45725001_1 - 2e-12 47.3 3.3 0.0017 19.0 0.0 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001127559.2_45725001_1 - 0.0039 17.3 0.0 1.9 8.7 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Itfg2 PF15907.3 001127559.2_45725001_1 - 0.032 13.2 0.1 0.23 10.4 0.0 2.2 2 1 1 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 Takusan PF04822.11 001009968.1_45722001_1 - 8.9e-26 89.5 6.3 8.9e-26 89.5 6.3 2.3 3 0 0 3 3 3 1 Takusan DUF616 PF04765.11 001009968.1_45722001_1 - 0.0009 18.4 0.3 0.0014 17.8 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF616) Seryl_tRNA_N PF02403.20 001009968.1_45722001_1 - 0.015 15.4 9.6 0.35 11.0 1.6 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.6 001009968.1_45722001_1 - 0.021 12.2 8.0 0.023 12.1 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.10 001009968.1_45722001_1 - 0.031 14.2 6.8 1.5 8.8 2.5 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.19 001009968.1_45722001_1 - 0.064 13.2 1.6 0.064 13.2 1.6 3.6 2 2 1 3 3 3 0 bZIP transcription factor DUF972 PF06156.11 001009968.1_45722001_1 - 0.11 13.0 16.3 0.12 12.8 1.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) KASH_CCD PF14662.4 001009968.1_45722001_1 - 0.17 11.6 14.1 0.33 10.6 14.1 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TLE_N PF03920.13 001009968.1_45722001_1 - 0.36 10.8 8.3 2.9 7.9 1.5 2.4 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Phage_HK97_TLTM PF06120.9 001009968.1_45722001_1 - 0.52 9.3 6.4 0.14 11.2 2.7 1.7 1 1 1 2 2 2 0 Tail length tape measure protein Cnn_1N PF07989.9 001009968.1_45722001_1 - 0.54 10.3 13.3 4.3 7.4 6.4 2.8 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Cep57_CLD_2 PF14197.4 001009968.1_45722001_1 - 0.64 10.0 10.5 0.13 12.2 2.8 2.6 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 PRKG1_interact PF15898.3 001009968.1_45722001_1 - 3 8.7 15.4 0.22 12.3 1.3 2.5 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FtsL PF04999.11 001009968.1_45722001_1 - 8.1 6.4 10.0 0.28 11.1 1.1 2.7 2 1 1 3 3 3 0 Cell division protein FtsL LRR_4 PF12799.5 001191613.1_45727001_1 - 2.1e-40 135.8 82.7 4e-08 33.3 2.5 12.7 9 3 6 15 15 15 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001191613.1_45727001_1 - 3.9e-32 111.0 28.5 3.6e-12 46.0 5.2 7.9 3 3 5 8 8 8 6 Leucine-rich repeat LRR_8 PF13855.4 001191613.1_45727001_1 - 4.3e-25 87.1 76.1 3.4e-07 29.8 6.4 10.9 7 2 5 12 12 12 8 Leucine rich repeat LRR_6 PF13516.4 001191613.1_45727001_1 - 0.11 12.4 0.1 0.11 12.4 0.1 11.7 11 1 1 12 12 12 0 Leucine Rich repeat Sialidase_penC PF12135.6 001191613.1_45727001_1 - 0.36 10.5 3.0 0.96 9.1 3.0 1.8 1 0 0 1 1 1 0 Sialidase enzyme penultimate C terminal domain LRR_1 PF00560.31 001191613.1_45727001_1 - 0.48 11.0 0.1 0.48 11.0 0.1 15.9 17 0 0 17 17 17 0 Leucine Rich Repeat Ada3 PF10198.7 001191613.1_45727001_1 - 2.1 8.4 6.3 13 5.8 0.1 2.5 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 LRR_2 PF07723.11 001191613.1_45727001_1 - 2.4 8.8 7.5 73 4.1 0.1 6.3 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_5 PF13306.4 001191613.1_45727001_1 - 3.4 7.5 15.3 2 8.3 1.6 5.1 4 2 0 4 4 4 0 Leucine rich repeats (6 copies) Metallophos PF00149.26 001130569.1_45727001_1 - 2.7e-10 41.0 0.6 3.9e-10 40.4 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.5 001130569.1_45727001_1 - 4.2e-06 27.0 0.0 4.5e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WAP PF00095.19 001106538.1_45723001_3 - 3.7e-13 49.5 39.4 5.8e-07 29.7 15.5 2.7 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Semenogelin PF05474.9 001102417.1_45723001_3 - 6.3e-08 31.5 10.5 6.3e-08 31.5 10.5 1.9 1 1 1 2 2 2 1 Semenogelin LRS4 PF10422.7 001102417.1_45723001_3 - 0.65 9.4 11.4 0.89 8.9 11.4 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DOR PF14839.4 001102417.1_45723001_3 - 1.8 8.3 9.1 2.6 7.8 9.1 1.3 1 0 0 1 1 1 0 DOR family Dus PF01207.15 001135803.1_45724001_2 - 5e-73 245.8 0.1 6.5e-73 245.4 0.1 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.19 001135803.1_45724001_2 - 0.00093 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.12 001135803.1_45724001_2 - 0.0093 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.15 001135803.1_45724001_2 - 0.026 13.7 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI MR_MLE_C PF13378.4 001135803.1_45724001_2 - 0.087 12.3 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Enolase C-terminal domain-like RhoGEF PF00621.18 001271313.1_45729001_3 - 5.7e-08 33.1 0.0 1.9e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.27 001271313.1_45729001_3 - 0.00027 21.3 0.0 0.00053 20.3 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_10 PF15411.4 001271313.1_45729001_3 - 0.037 14.2 0.4 0.12 12.5 0.4 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.3 001271313.1_45729001_3 - 0.11 12.4 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 PH domain CCDC24 PF15669.3 001134626.1_45724001_3 - 1.6e-64 217.4 8.3 2.3e-64 216.9 8.3 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Cytidylate_kin PF02224.16 001134626.1_45724001_3 - 0.079 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase His_kinase PF06580.11 001134626.1_45724001_3 - 0.17 12.1 0.8 0.44 10.8 0.2 1.9 2 0 0 2 2 2 0 Histidine kinase betaPIX_CC PF16523.3 001134626.1_45724001_3 - 0.44 10.3 2.6 1.5 8.6 0.7 2.2 2 0 0 2 2 2 0 betaPIX coiled coil Ank_5 PF13857.4 001012112.1_45723001_3 - 2.4e-06 27.6 0.0 8.7e-05 22.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.4 001012112.1_45723001_3 - 5.1e-05 23.6 0.1 0.0026 18.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.4 001012112.1_45723001_3 - 0.0039 17.4 1.7 0.038 14.4 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.28 001012112.1_45723001_3 - 0.0054 17.0 0.1 0.034 14.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.5 001012112.1_45723001_3 - 0.018 15.5 0.0 0.099 13.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) ER PF01133.15 001134511.1_45722001_1 - 2.2e-38 130.1 0.0 2.7e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Enhancer of rudimentary MTS PF05175.12 001106853.1_45724001_3 - 5.5e-11 42.2 0.0 1.4e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.4 001106853.1_45724001_3 - 3.9e-10 39.6 0.0 5.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001106853.1_45724001_3 - 3.8e-09 37.0 0.0 6.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.11 001106853.1_45724001_3 - 4.7e-08 32.6 0.0 3.4e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.13 001106853.1_45724001_3 - 4.3e-06 26.4 0.0 6.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.15 001106853.1_45724001_3 - 2.3e-05 23.8 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.16 001106853.1_45724001_3 - 4.8e-05 23.0 0.0 0.00014 21.5 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.10 001106853.1_45724001_3 - 0.00016 22.2 0.0 0.00025 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 001106853.1_45724001_3 - 0.00053 20.4 0.0 0.00098 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.4 001106853.1_45724001_3 - 0.0013 19.6 0.0 0.0033 18.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.7 001106853.1_45724001_3 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.5 001106853.1_45724001_3 - 0.0038 17.0 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.4 001106853.1_45724001_3 - 0.0056 16.5 0.1 0.012 15.4 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.8 001106853.1_45724001_3 - 0.0092 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltr_RsmB-F PF01189.15 001106853.1_45724001_3 - 0.026 14.0 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.4 001106853.1_45724001_3 - 0.043 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.8 001106853.1_45724001_3 - 0.057 13.0 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.15 001106853.1_45724001_3 - 0.059 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.10 001106853.1_45724001_3 - 0.093 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.17 001106853.1_45724001_3 - 0.22 11.1 0.0 0.33 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CEP19 PF14933.4 001106854.1_45726001_2 - 0.041 14.0 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 CEP19-like protein E1-E2_ATPase PF00122.18 001191657.1_45729001_1 - 7e-36 123.5 0.3 1.7e-35 122.2 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.6 001191657.1_45729001_1 - 1.9e-29 102.1 0.7 4e-29 101.1 0.7 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.24 001191657.1_45729001_1 - 4.8e-14 53.0 0.0 5.9e-09 36.4 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.24 001191657.1_45729001_1 - 3.4e-07 29.7 0.0 8.4e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.4 001191657.1_45729001_1 - 2.1e-06 27.6 0.0 4.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2620 PF10941.6 001191657.1_45729001_1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2620 FtsL PF04999.11 001191657.1_45729001_1 - 0.15 11.9 1.4 1.9 8.4 0.6 2.5 2 0 0 2 2 2 0 Cell division protein FtsL Cation_ATPase_C PF00689.19 001191657.1_45729001_1 - 2.7 7.5 19.2 0.023 14.3 9.8 2.4 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus Ank_2 PF12796.5 001191565.1_45724001_1 - 3.2e-20 72.4 0.2 5.8e-12 45.9 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001191565.1_45724001_1 - 1.3e-17 63.8 1.0 1.1e-06 28.9 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.4 001191565.1_45724001_1 - 1.3e-17 63.5 2.0 1.4e-06 28.4 0.1 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 001191565.1_45724001_1 - 2.1e-10 39.8 1.0 0.039 14.4 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.28 001191565.1_45724001_1 - 6.7e-08 32.5 0.1 0.00014 22.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Solute_trans_a PF03619.14 001173370.1_45727001_3 - 3.6e-92 308.5 19.5 4.7e-92 308.2 19.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3936 PF13072.4 001134730.1_45728001_1 - 0.017 14.8 0.1 0.034 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) Gal-bind_lectin PF00337.20 001134730.1_45728001_3 - 2.6e-27 94.8 0.0 3.8e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin ATP12 PF07542.9 001107006.1_45723001_3 - 1.6e-39 134.8 0.2 2.4e-39 134.2 0.2 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein zf-H2C2_2 PF13465.4 001107097.1_45729001_2 - 4.8e-41 137.3 92.0 9.9e-08 32.0 0.2 14.8 15 0 0 15 15 15 9 Zinc-finger double domain zf-C2H2 PF00096.24 001107097.1_45729001_2 - 9.8e-32 107.5 110.3 0.0015 18.7 0.6 14.3 15 0 0 15 15 14 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001107097.1_45729001_2 - 5.8e-29 98.1 104.0 0.005 17.4 0.9 14.3 15 0 0 15 15 13 12 C2H2-type zinc finger BTB PF00651.29 001107097.1_45729001_2 - 9.1e-21 74.0 1.3 1.9e-20 73.0 1.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.4 001107097.1_45729001_2 - 4.8e-13 48.6 76.9 0.00067 19.4 0.9 12.2 12 1 0 12 12 12 8 C2H2-type zinc finger zf-Di19 PF05605.10 001107097.1_45729001_2 - 2.5e-06 27.5 43.5 0.0014 18.8 0.7 7.4 3 1 3 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.6 001107097.1_45729001_2 - 3.3e-06 27.1 55.4 0.45 10.8 0.2 12.0 12 0 0 12 12 12 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.5 001107097.1_45729001_2 - 4.9e-05 23.5 55.9 1.2 9.4 0.2 9.9 3 1 5 9 9 9 3 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.4 001107097.1_45729001_2 - 0.011 15.5 1.0 0.011 15.5 1.0 5.0 7 1 0 7 7 7 0 HNH endonuclease Ta0938 PF11494.6 001107097.1_45729001_2 - 0.022 14.9 9.8 3.6 7.8 0.0 4.3 3 2 1 5 5 5 0 Ta0938 zf-met PF12874.5 001107097.1_45729001_2 - 0.053 13.8 0.2 0.053 13.8 0.2 10.5 11 0 0 11 11 10 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 001107097.1_45729001_2 - 0.074 12.7 0.0 0.074 12.7 0.0 10.3 12 0 0 12 12 11 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.3 001107097.1_45729001_2 - 4.6 7.0 15.6 9 6.1 0.0 6.3 6 1 1 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-C3HC4_2 PF13923.4 001107144.1_45729001_1 - 1.3e-09 37.6 12.8 3.3e-09 36.3 12.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001107144.1_45729001_1 - 8.2e-09 35.5 13.0 3.6e-08 33.4 13.0 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.4 001107144.1_45729001_1 - 9.4e-08 31.7 9.3 9.4e-08 31.7 9.3 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001107144.1_45729001_1 - 1.4e-07 31.3 8.4 4.2e-07 29.7 8.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001107144.1_45729001_1 - 4.7e-07 29.4 11.8 1.2e-06 28.2 11.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001107144.1_45729001_1 - 1.2e-05 25.0 9.8 3.2e-05 23.7 9.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.4 001107144.1_45729001_1 - 2.2e-05 24.1 9.7 6.5e-05 22.6 9.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.5 001107144.1_45729001_1 - 4.2e-05 23.6 9.6 0.00015 21.9 9.6 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.4 001107144.1_45729001_1 - 0.0061 16.5 12.3 0.016 15.3 12.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.5 001107144.1_45729001_1 - 0.44 10.5 5.6 1.2 9.1 5.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.6 001107144.1_45729001_1 - 7.1 6.4 6.7 14 5.5 6.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit AKAP2_C PF15304.4 001107161.1_45723001_1 - 6.8e-27 94.5 18.3 1.3e-12 47.6 2.3 3.5 2 1 0 3 3 3 3 A-kinase anchor protein 2 C-terminus BTB PF00651.29 001134991.1_45725001_2 - 7.5e-22 77.5 0.6 1.3e-21 76.8 0.6 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.24 001134991.1_45725001_2 - 6.8e-13 48.2 30.2 1.2e-05 25.3 2.8 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001134991.1_45725001_2 - 7e-11 41.9 28.4 0.009 16.6 1.9 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001134991.1_45725001_2 - 1e-08 35.1 26.8 7.4e-05 22.9 1.3 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.4 001134991.1_45725001_2 - 0.00081 19.0 1.0 0.00081 19.0 1.0 4.0 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.5 001134991.1_45725001_2 - 0.01 16.0 17.4 1.4 9.1 0.3 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.5 001134991.1_45725001_2 - 0.016 15.4 15.7 0.27 11.5 1.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.10 001134991.1_45725001_2 - 0.079 13.1 17.0 0.21 11.8 5.8 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.3 001134991.1_45725001_2 - 0.72 9.6 4.5 0.93 9.3 0.5 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.3 001134991.1_45725001_2 - 1.7 9.3 7.6 11 6.8 7.3 2.5 1 1 1 2 2 2 0 zinc-ribbon family HypA PF01155.17 001134991.1_45725001_2 - 1.9 8.4 4.2 1.8 8.5 1.6 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.5 001134991.1_45725001_2 - 3.1 7.7 5.8 2.4 8.1 1.9 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_11 PF16622.3 001134991.1_45725001_2 - 3.9 7.2 22.6 2.2 8.0 0.3 3.8 4 0 0 4 4 3 0 zinc-finger C2H2-type zinc_ribbon_10 PF10058.7 001134991.1_45725001_2 - 4.6 6.9 7.8 7.2 6.3 0.2 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.8 001134991.1_45725001_2 - 9.1 6.4 8.5 1.7 8.7 0.9 3.0 2 1 1 3 3 3 0 Zinc ribbon domain zf-CHCC PF10276.7 001134991.1_45725001_2 - 9.8 6.2 7.1 1.7 8.6 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger domain YhhN PF07947.12 001135016.1_45724001_2 - 8.5e-44 149.2 25.8 1.4e-43 148.5 25.8 1.3 1 0 0 1 1 1 1 YhhN family Asp PF00026.21 020091.1_45723001_2 - 2.4e-108 362.1 0.0 3e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 020091.1_45723001_2 - 2.7e-15 57.0 0.1 1.3e-09 38.4 0.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 020091.1_45723001_2 - 5.3e-14 51.6 0.6 8.3e-14 51.0 0.6 1.3 1 0 0 1 1 1 1 A1 Propeptide Pkinase PF00069.23 001107224.2_45723001_1 - 2e-64 217.4 0.0 2.6e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001107224.2_45723001_1 - 5.9e-37 127.2 0.0 7.7e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001107224.2_45723001_1 - 4.2e-09 36.0 0.0 5.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.21 001107224.2_45723001_1 - 0.0026 17.6 0.5 0.0054 16.5 0.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.12 001107224.2_45723001_1 - 0.076 12.2 0.4 0.16 11.2 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin PF00085.18 001100529.1_45729001_1 - 2.5e-11 43.3 0.0 4.1e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF1510 PF07423.9 001100529.1_45729001_1 - 0.0018 17.6 11.8 0.0033 16.8 11.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CDC45 PF02724.12 001100529.1_45729001_1 - 0.015 13.5 4.8 0.021 13.0 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4834 PF16118.3 001100529.1_45729001_1 - 0.027 15.3 1.7 0.028 15.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MAP17 PF15807.3 001100529.1_45729001_1 - 0.13 12.3 0.3 0.42 10.7 0.3 1.8 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 IncA PF04156.12 001100529.1_45729001_1 - 0.16 11.7 0.5 0.26 10.9 0.5 1.2 1 0 0 1 1 1 0 IncA protein FAM176 PF14851.4 001100529.1_45729001_1 - 0.2 11.2 11.4 1.3 8.6 11.3 2.1 1 1 0 1 1 1 0 FAM176 family zf-H2C2_2 PF13465.4 001017512.2_45725001_3 - 8.6e-61 199.7 50.4 5.1e-09 36.0 0.4 10.0 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.24 001017512.2_45725001_3 - 3e-41 137.5 58.0 1.9e-06 27.9 3.1 9.4 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001017512.2_45725001_3 - 1.3e-20 72.1 62.6 0.0038 17.8 2.5 9.6 9 0 0 9 9 9 8 C2H2-type zinc finger KRAB PF01352.25 001017512.2_45725001_3 - 1.5e-19 69.2 0.6 3e-19 68.3 0.6 1.5 1 0 0 1 1 1 1 KRAB box zf-met PF12874.5 001017512.2_45725001_3 - 2.9e-11 43.2 46.6 0.00066 19.8 1.7 8.6 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001017512.2_45725001_3 - 7.5e-11 41.9 29.6 0.01 16.0 0.0 8.3 9 0 0 9 9 8 3 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001017512.2_45725001_3 - 5e-06 26.4 35.1 0.03 14.3 0.8 6.4 4 2 3 7 7 7 4 Zinc ribbon domain zf-C2H2_6 PF13912.4 001017512.2_45725001_3 - 0.00018 21.2 46.4 0.21 11.5 1.6 9.3 9 0 0 9 9 9 3 C2H2-type zinc finger C1_4 PF07975.10 001017512.2_45725001_3 - 0.00027 21.0 34.1 0.022 14.9 4.8 5.5 3 1 3 6 6 5 3 TFIIH C1-like domain HypA PF01155.17 001017512.2_45725001_3 - 0.0052 16.7 25.9 0.074 12.9 7.9 4.6 1 1 4 5 5 5 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-LYAR PF08790.9 001017512.2_45725001_3 - 0.013 15.3 0.1 0.013 15.3 0.1 6.6 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger HNH PF01844.21 001017512.2_45725001_3 - 0.049 13.7 0.2 0.049 13.7 0.2 7.6 9 0 0 9 9 9 0 HNH endonuclease ADK_lid PF05191.12 001017512.2_45725001_3 - 0.062 13.2 24.3 5 7.1 3.1 6.3 3 2 2 6 6 5 0 Adenylate kinase, active site lid DUF3268 PF11672.6 001017512.2_45725001_3 - 0.44 10.8 26.2 1.9 8.7 3.1 4.7 1 1 5 7 7 7 0 zinc-finger-containing domain zf-trcl PF13451.4 001017512.2_45725001_3 - 0.8 9.5 32.7 3.2 7.6 0.1 8.5 8 1 1 9 9 9 0 Probable zinc-ribbon domain BolA PF01722.16 001017512.2_45725001_3 - 4.4 7.5 6.2 20 5.4 0.4 3.4 2 1 0 3 3 3 0 BolA-like protein BRO1 PF03097.16 001107505.1_45727001_2 - 1.4e-89 300.5 0.1 2e-89 300.0 0.1 1.2 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.14 001107505.1_45727001_2 - 1.9e-14 53.4 3.4 4.9e-14 52.1 3.4 1.7 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.22 001107505.1_45727001_2 - 0.00086 19.5 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) HD_4 PF13328.4 001107528.1_45724001_2 - 1.4e-23 83.3 0.2 2e-23 82.7 0.2 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.20 001107528.1_45724001_2 - 5.5e-06 26.5 0.5 1.3e-05 25.3 0.5 1.7 1 0 0 1 1 1 1 HD domain zf-H2C2_2 PF13465.4 001014056.1_45724001_2 - 5.3e-24 83.4 26.5 9.6e-08 32.0 1.8 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.24 001014056.1_45724001_2 - 6.2e-22 76.6 24.6 1.5e-05 25.1 3.7 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.4 001014056.1_45724001_2 - 3.2e-12 45.9 17.5 0.004 16.9 0.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_4 PF13894.4 001014056.1_45724001_2 - 1.9e-11 43.6 25.5 0.025 15.2 0.4 5.2 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001014056.1_45724001_2 - 6.6e-09 35.7 3.9 0.05 13.8 0.7 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding DUF3669 PF12417.6 001014056.1_45724001_2 - 7.1e-06 26.0 0.1 1.6e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Zinc finger protein zf-LYAR PF08790.9 001014056.1_45724001_2 - 0.00053 19.7 8.6 0.25 11.2 1.5 4.6 4 0 0 4 4 4 1 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.8 001014056.1_45724001_2 - 0.0095 15.9 11.5 2 8.5 3.1 4.3 2 1 2 4 4 4 2 Zinc ribbon domain C1_1 PF00130.20 001014056.1_45724001_2 - 0.042 13.6 7.5 0.55 10.0 0.1 3.6 1 1 3 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-trcl PF13451.4 001014056.1_45724001_2 - 0.055 13.2 10.7 0.29 10.9 3.1 3.9 3 0 0 3 3 3 0 Probable zinc-ribbon domain XPA_N PF01286.16 001014056.1_45724001_2 - 0.073 13.0 6.2 15 5.6 0.0 4.4 4 0 0 4 4 4 0 XPA protein N-terminal BDHCT_assoc PF16204.3 001014056.1_45724001_2 - 0.095 12.2 0.5 0.19 11.2 0.5 1.5 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein KRAB PF01352.25 001014056.1_45724001_2 - 0.11 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 KRAB box zf-C2HE PF16278.3 001014056.1_45724001_2 - 0.12 12.7 16.6 5.9 7.3 0.7 5.2 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_9 PF14369.4 001014056.1_45724001_2 - 0.34 11.1 7.2 1.3 9.3 0.0 4.2 4 0 0 4 4 4 0 zinc-ribbon C1_4 PF07975.10 001014056.1_45724001_2 - 0.41 10.8 10.2 3.2 7.9 0.7 3.0 2 1 0 2 2 2 0 TFIIH C1-like domain SprT-like PF10263.7 001014056.1_45724001_2 - 0.52 10.0 13.0 0.23 11.1 5.7 2.6 1 1 1 2 2 2 0 SprT-like family zf-AN1 PF01428.14 001014056.1_45724001_2 - 0.58 10.2 11.4 40 4.4 0.1 4.6 4 0 0 4 4 4 0 AN1-like Zinc finger SlyX PF04102.10 001014056.1_45724001_2 - 1.2 9.7 4.7 1.6 9.3 0.1 2.8 2 0 0 2 2 2 0 SlyX PHD PF00628.27 001014056.1_45724001_2 - 1.9 8.3 7.5 3.2 7.6 1.2 3.1 2 0 0 2 2 2 0 PHD-finger DNA_RNApol_7kD PF03604.11 001014056.1_45724001_2 - 2.1 7.9 10.9 11 5.6 0.2 4.9 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.5 001014056.1_45724001_2 - 3.2 7.7 13.4 0.38 10.7 2.3 3.1 3 0 0 3 3 3 0 Double zinc ribbon zf-CHY PF05495.10 001014056.1_45724001_2 - 3.4 8.2 15.7 3.1e+02 1.9 12.1 3.5 2 1 0 2 2 1 0 CHY zinc finger zf-met PF12874.5 001014056.1_45724001_2 - 6.1 7.2 16.7 7.5 7.0 2.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Hormone_4 PF00220.15 001106156.1_45725001_2 - 0.98 9.4 7.2 0.22 11.4 1.4 3.0 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain PKD_channel PF08016.10 001106156.1_45725001_3 - 1.2e-130 435.9 22.1 1.2e-130 435.9 22.1 2.0 3 0 0 3 3 3 1 Polycystin cation channel Ion_trans PF00520.29 001106156.1_45725001_3 - 8.5e-18 64.3 35.5 8.5e-18 64.3 35.5 2.0 2 0 0 2 2 2 1 Ion transport protein G-patch PF01585.21 001034157.2_45723001_1 - 1.5e-13 50.2 0.5 4.1e-13 48.9 0.5 1.8 1 0 0 1 1 1 1 G-patch domain Ank_2 PF12796.5 001034157.2_45723001_1 - 1.2e-05 25.7 0.0 2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001034157.2_45723001_1 - 4.1e-05 23.9 0.0 7.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.4 001034157.2_45723001_1 - 5.6e-05 23.3 0.7 0.0029 17.8 0.7 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001034157.2_45723001_1 - 0.00031 20.8 0.0 0.0061 16.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat G-patch_2 PF12656.5 001034157.2_45723001_1 - 0.073 13.0 0.2 0.21 11.6 0.2 1.8 1 0 0 1 1 1 0 G-patch domain MHC_I PF00129.16 001008854.2_45723001_1 - 2.7e-41 140.9 0.1 4.9e-41 140.1 0.1 1.4 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001008854.2_45723001_1 - 2.8e-14 53.2 0.1 9.2e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain ig PF00047.23 001008854.2_45723001_1 - 0.00062 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001008854.2_45723001_1 - 0.0011 19.4 0.1 0.026 15.0 0.0 2.5 1 1 1 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.10 001008854.2_45723001_1 - 0.0017 18.2 0.0 0.0045 16.9 0.0 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain TMEM154 PF15102.4 001008854.2_45723001_1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.4 001008854.2_45723001_1 - 0.036 14.2 0.1 0.066 13.3 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4448 PF14610.4 001008854.2_45723001_1 - 0.087 12.5 0.1 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Ig_2 PF13895.4 001008854.2_45723001_1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain AA_permease_2 PF13520.4 001017465.1_45724001_3 - 1.3e-49 169.0 38.3 1.7e-49 168.7 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.19 001017465.1_45724001_3 - 1.8e-27 96.0 34.9 3e-27 95.2 34.9 1.3 1 0 0 1 1 1 1 Amino acid permease IPP-2 PF04979.12 001017476.1_45723001_2 - 1.5e-28 100.0 8.4 2.1e-28 99.5 5.5 2.3 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Varsurf_PPLC PF03490.11 001107671.1_45724001_3 - 0.0093 15.7 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C Ank_2 PF12796.5 001191638.1_45722001_1 - 2.1e-21 76.2 0.4 9.7e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001191638.1_45722001_1 - 7.4e-21 73.5 0.5 1.1e-07 31.8 0.1 3.9 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.4 001191638.1_45722001_1 - 4.8e-20 71.5 1.1 1.8e-07 31.4 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.4 001191638.1_45722001_1 - 9.2e-19 67.1 2.9 1.5e-10 41.0 0.2 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.4 001191638.1_45722001_1 - 1e-14 53.0 1.9 4.2e-06 26.6 0.1 4.9 4 0 0 4 4 4 2 Ankyrin repeat UPF0542 PF15086.4 001191638.1_45722001_1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 UPF0258 PF06789.10 001106144.2_45724001_3 - 9.2e-37 126.6 0.0 1.5e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) Wzy_C PF04932.13 001106144.2_45724001_3 - 1.3 8.5 4.8 1.5 8.3 2.1 2.0 2 0 0 2 2 2 0 O-Antigen ligase UPAR_LY6 PF00021.19 001170329.1_45722001_1 - 2.2e-05 24.9 3.3 3.5e-05 24.3 0.8 2.4 2 0 0 2 2 2 1 u-PAR/Ly-6 domain SWIM PF04434.15 001107801.1_45726001_1 - 1.2e-06 27.9 4.1 1.2e-06 27.9 4.1 1.9 2 0 0 2 2 2 1 SWIM zinc finger MULE PF10551.7 001107801.1_45726001_1 - 0.00011 22.5 0.0 0.00029 21.2 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.15 001107801.1_45726001_1 - 0.018 14.6 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Transposase PAH PF02671.19 001107801.1_45726001_1 - 0.11 12.5 0.3 14 5.8 0.0 3.2 2 0 0 2 2 2 0 Paired amphipathic helix repeat Torsin PF06309.9 001107816.1_45727001_1 - 2.8e-12 46.7 0.0 5.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.4 001107816.1_45727001_1 - 1.1e-08 35.3 0.6 3.1e-06 27.4 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.4 001107816.1_45727001_1 - 2.9e-07 30.9 4.4 2e-05 24.9 4.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.12 001107816.1_45727001_1 - 0.00018 21.4 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.27 001107816.1_45727001_1 - 0.00018 21.8 0.0 0.00036 20.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.4 001107816.1_45727001_1 - 0.0097 16.3 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.4 001107816.1_45727001_1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.16 001107816.1_45727001_1 - 0.077 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.4 001107816.1_45727001_1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.4 001107816.1_45727001_1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PCRF PF03462.16 001107816.1_45727001_1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 1 1 2 2 2 0 PCRF domain zf-H2C2_2 PF13465.4 001163063.1_45726001_2 - 1e-105 341.7 126.6 6e-10 39.0 0.8 17.3 17 0 0 17 17 17 15 Zinc-finger double domain zf-C2H2 PF00096.24 001163063.1_45726001_2 - 8.8e-62 202.2 117.1 4.6e-06 26.7 0.4 14.8 14 0 0 14 14 14 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001163063.1_45726001_2 - 5.4e-47 154.2 116.1 0.00024 21.5 1.3 15.3 15 0 0 15 15 15 14 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001163063.1_45726001_2 - 2.7e-25 87.6 108.1 0.00018 21.3 0.5 14.9 15 0 0 15 15 14 13 C2H2-type zinc finger KRAB PF01352.25 001163063.1_45726001_2 - 3.2e-20 71.4 0.2 5e-20 70.8 0.2 1.3 1 0 0 1 1 1 1 KRAB box zf-C2H2_11 PF16622.3 001163063.1_45726001_2 - 2.5e-11 43.0 67.0 0.038 13.6 0.4 13.9 14 0 0 14 14 14 9 zinc-finger C2H2-type Zn-ribbon_8 PF09723.8 001163063.1_45726001_2 - 4.3e-10 39.4 75.3 0.042 13.8 2.4 10.0 3 2 10 13 13 13 12 Zinc ribbon domain DUF3268 PF11672.6 001163063.1_45726001_2 - 4.5e-09 36.5 52.7 0.054 13.7 0.7 7.8 5 1 3 9 9 9 8 zinc-finger-containing domain C1_4 PF07975.10 001163063.1_45726001_2 - 5e-06 26.6 72.8 0.0065 16.6 4.4 9.7 3 2 7 11 11 11 4 TFIIH C1-like domain zf-C2H2_jaz PF12171.6 001163063.1_45726001_2 - 0.00033 20.8 90.6 0.039 14.1 0.1 13.6 14 0 0 14 14 14 7 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.3 001163063.1_45726001_2 - 0.0011 19.5 67.8 0.27 11.9 3.0 7.9 2 2 3 8 8 8 7 zinc-ribbon family XPA_N PF01286.16 001163063.1_45726001_2 - 0.0054 16.6 60.3 12 5.9 0.2 14.2 14 0 0 14 14 14 0 XPA protein N-terminal CpXC PF14353.4 001163063.1_45726001_2 - 0.055 13.4 60.8 1.9 8.4 0.2 12.6 8 3 2 12 12 12 0 CpXC protein BDHCT_assoc PF16204.3 001163063.1_45726001_2 - 0.26 10.8 8.9 3.6 7.1 0.1 4.2 1 1 5 6 6 6 0 BDHCT-box associated domain on Bloom syndrome protein Nuc_sug_transp PF04142.13 001107924.1_45724001_3 - 1.6e-121 405.2 23.6 2.2e-121 404.7 23.6 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.18 001107924.1_45724001_3 - 0.04 13.9 32.3 0.9 9.6 7.9 3.1 2 1 0 2 2 2 0 EamA-like transporter family FAM110_N PF14161.4 001244770.1_45724001_1 - 1.5e-35 121.7 1.1 2.7e-35 120.9 1.1 1.4 1 0 0 1 1 1 1 Centrosome-associated N terminus FAM110_C PF14160.4 001244770.1_45724001_1 - 3.8e-30 105.1 0.0 5.6e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Centrosome-associated C terminus TRAM_LAG1_CLN8 PF03798.14 001108136.1_45722001_1 - 3.3e-13 49.7 9.1 4.7e-13 49.2 9.1 1.3 1 0 0 1 1 1 1 TLC domain DUF2431 PF10354.7 001108145.1_45724001_2 - 1.4e-26 93.6 0.0 2.3e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.12 001108145.1_45724001_2 - 1.9e-16 60.1 0.0 3.4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain G-gamma PF00631.20 053660.2_45723001_3 - 5.4e-14 51.8 0.0 7.7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 GGL domain Ras PF00071.20 001025753.1_45724001_2 - 3.2e-30 104.8 0.0 4.1e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001025753.1_45724001_2 - 5.5e-09 36.2 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001025753.1_45724001_2 - 0.00015 21.1 0.0 0.00021 20.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.16 001025753.1_45724001_2 - 0.0014 18.0 0.0 0.0046 16.4 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RuvB_N PF05496.10 001025753.1_45724001_2 - 0.0018 17.4 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.4 001025753.1_45724001_2 - 0.004 17.3 0.2 0.091 12.9 0.0 2.7 1 1 1 3 3 3 1 AAA domain AAA_16 PF13191.4 001025753.1_45724001_2 - 0.0068 16.7 1.8 0.035 14.3 1.8 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.14 001025753.1_45724001_2 - 0.0075 16.0 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.4 001025753.1_45724001_2 - 0.0097 16.3 0.0 0.028 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.27 001025753.1_45724001_2 - 0.0098 16.2 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.25 001025753.1_45724001_2 - 0.011 16.2 0.0 0.055 13.8 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.12 001025753.1_45724001_2 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.4 001025753.1_45724001_2 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.4 001025753.1_45724001_2 - 0.032 14.3 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.21 001025753.1_45724001_2 - 0.16 12.0 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.13 001025753.1_45724001_2 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 NTPase zf-H2C2_2 PF13465.4 001191664.1_45726001_1 - 7.3e-83 269.5 140.6 2.7e-08 33.8 1.5 19.0 21 0 0 21 21 21 14 Zinc-finger double domain zf-C2H2 PF00096.24 001191664.1_45726001_1 - 6.4e-75 243.5 151.2 5.5e-07 29.6 0.8 18.2 18 0 0 18 18 18 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001191664.1_45726001_1 - 1.3e-39 131.3 143.7 0.0002 21.8 0.6 18.1 18 0 0 18 18 18 15 C2H2-type zinc finger KRAB PF01352.25 001191664.1_45726001_1 - 1.2e-21 75.9 0.4 2.3e-21 75.1 0.4 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001191664.1_45726001_1 - 4e-19 68.0 132.3 0.00036 20.3 0.4 17.6 18 1 0 18 18 18 14 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001191664.1_45726001_1 - 2.1e-07 30.8 104.5 0.013 15.5 2.5 12.9 5 3 9 14 14 14 11 Zinc ribbon domain zf-C2H2_jaz PF12171.6 001191664.1_45726001_1 - 0.00018 21.6 97.6 0.46 10.7 0.1 16.8 17 0 0 17 17 17 8 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.3 001191664.1_45726001_1 - 3.4 8.4 80.1 2.5 8.8 1.9 9.8 3 3 6 10 10 10 0 zinc-ribbon family XPA_N PF01286.16 001191664.1_45726001_1 - 5 7.1 91.2 5.1 7.1 1.5 17.0 18 0 0 18 18 18 0 XPA protein N-terminal zf-H2C2_2 PF13465.4 001025677.1_45724001_1 - 4.7e-62 203.7 56.3 9.5e-09 35.2 3.1 9.5 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.24 001025677.1_45724001_1 - 2.6e-41 137.7 69.4 1.3e-05 25.2 0.9 9.4 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001025677.1_45724001_1 - 3e-22 77.2 65.3 0.0037 17.8 1.3 9.1 9 0 0 9 9 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001025677.1_45724001_1 - 2.1e-09 37.0 40.3 0.33 10.8 0.2 8.6 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_11 PF16622.3 001025677.1_45724001_1 - 1.6e-08 34.0 46.1 0.0026 17.4 3.3 8.5 8 0 0 8 8 8 5 zinc-finger C2H2-type HypA PF01155.17 001025677.1_45724001_1 - 1.8e-05 24.6 24.2 0.13 12.1 2.9 4.7 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.8 001025677.1_45724001_1 - 3e-05 23.9 35.9 0.1 12.6 1.3 5.8 4 1 1 5 5 5 3 Zinc ribbon domain zinc_ribbon_15 PF17032.3 001025677.1_45724001_1 - 4.9e-05 23.9 27.8 0.077 13.6 1.5 4.9 1 1 5 6 6 6 5 zinc-ribbon family C1_1 PF00130.20 001025677.1_45724001_1 - 0.00023 20.9 33.1 0.11 12.2 1.5 6.0 3 2 3 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.12 001025677.1_45724001_1 - 0.00025 20.9 18.9 0.31 11.0 0.2 6.0 3 2 2 5 5 5 2 Adenylate kinase, active site lid XPA_N PF01286.16 001025677.1_45724001_1 - 0.0025 17.7 40.4 1.7 8.6 0.2 8.8 9 0 0 9 9 8 1 XPA protein N-terminal YhfH PF14149.4 001025677.1_45724001_1 - 0.0033 17.2 30.0 5.3 7.0 0.1 8.2 8 0 0 8 8 8 1 YhfH-like protein LIM PF00412.20 001025677.1_45724001_1 - 0.0081 16.2 38.3 0.26 11.4 2.7 7.3 3 3 2 5 5 5 2 LIM domain zf-C2H2_jaz PF12171.6 001025677.1_45724001_1 - 0.019 15.1 31.5 2.7 8.3 0.0 8.0 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.4 001025677.1_45724001_1 - 0.17 11.8 31.1 8.2 6.4 0.1 7.8 1 1 5 7 7 7 0 CpXC protein Raffinose_syn PF05691.10 001025677.1_45724001_1 - 0.18 9.4 1.1 4 5.0 0.1 2.2 2 0 0 2 2 2 0 Raffinose synthase or seed imbibition protein Sip1 zf-LYAR PF08790.9 001025677.1_45724001_1 - 0.3 10.9 41.1 2.3 8.1 0.6 8.2 8 0 0 8 8 8 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.3 001025677.1_45724001_1 - 0.33 11.3 42.7 3.5 8.0 0.4 8.1 2 1 4 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.4 001025677.1_45724001_1 - 0.5 10.0 0.1 0.5 10.0 0.1 8.7 10 1 0 10 10 10 0 C2H2-type zinc-finger domain Zn_Tnp_IS1595 PF12760.5 001025677.1_45724001_1 - 0.62 10.0 39.2 0.6 10.0 4.0 5.6 3 2 3 6 6 6 0 Transposase zinc-ribbon domain zf-AN1 PF01428.14 001025677.1_45724001_1 - 0.67 10.0 43.3 6.3 6.9 0.1 8.5 6 2 2 8 8 8 0 AN1-like Zinc finger zinc_ribbon_4 PF13717.4 001025677.1_45724001_1 - 4.8 7.1 33.3 19 5.1 0.3 7.9 7 1 0 7 7 7 0 zinc-ribbon domain V-set PF07686.15 001029920.1_45725001_3 - 6.4e-06 26.2 0.0 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 001029920.1_45725001_3 - 0.00017 21.6 0.0 0.00038 20.4 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001029920.1_45725001_3 - 0.00061 20.2 0.0 0.0023 18.4 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001029920.1_45725001_3 - 0.053 13.5 0.0 0.25 11.3 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin I-set domain Izumo-Ig PF16706.3 001029920.1_45725001_3 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain IRS PF02174.15 032074.1_45724001_3 - 8.4e-25 86.4 0.0 1.5e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.27 032074.1_45724001_3 - 0.0012 19.2 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 032074.1_45724001_3 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Defensin_propep PF00879.16 001025763.1_45721001_1 - 3.5e-23 81.5 1.4 4.5e-23 81.2 1.4 1.1 1 0 0 1 1 1 1 Defensin propeptide MF_alpha_N PF05436.9 001025763.1_45721001_1 - 0.067 13.0 0.1 0.094 12.5 0.1 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Defensin_beta_2 PF13841.4 001025763.1_45721001_1 - 0.33 11.3 9.4 0.97 9.8 9.4 1.8 1 1 0 1 1 1 0 Beta defensin V-set PF07686.15 001108474.1_45723001_3 - 1.8e-13 50.5 0.0 2.9e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.4 001108474.1_45723001_3 - 7.7e-07 29.5 0.0 0.00014 22.2 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Receptor_2B4 PF11465.6 001108474.1_45723001_3 - 4.4e-05 23.5 0.0 0.0034 17.4 0.0 2.3 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 I-set PF07679.14 001108474.1_45723001_3 - 6.6e-05 22.8 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Herpes_gE PF02480.14 001108474.1_45723001_3 - 0.0043 15.7 0.0 0.09 11.4 0.0 2.0 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Adeno_E3_CR1 PF02440.13 001108474.1_45723001_3 - 0.019 14.6 0.1 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 ig PF00047.23 001108474.1_45723001_3 - 0.031 14.3 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.4 001108474.1_45723001_3 - 0.11 12.7 0.0 1.7 8.9 0.0 2.8 2 2 0 2 2 2 0 Immunoglobulin domain TMEM72 PF16054.3 001108643.1_45727001_3 - 1.2e-78 262.8 1.3 1.6e-78 262.4 1.3 1.1 1 0 0 1 1 1 1 Transmembrane protein family 72 FYVE PF01363.19 001108655.1_45726001_1 - 6.9e-18 64.4 9.4 1.7e-17 63.2 7.4 2.3 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.27 001108655.1_45726001_1 - 5.5e-10 39.6 0.1 1.4e-09 38.2 0.1 1.8 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.14 001108655.1_45726001_1 - 0.002 18.2 3.6 0.0047 17.0 3.6 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger PH_13 PF16652.3 001108655.1_45726001_1 - 0.24 11.2 0.9 2.5 7.8 0.9 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Rhodanese_C PF12368.6 001108663.1_45727001_2 - 1.6e-17 63.5 8.6 4.1e-17 62.2 8.6 1.8 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.18 001108663.1_45727001_2 - 6.5e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_hydro_47 PF01532.18 001108687.1_45728001_1 - 2.6e-143 478.1 0.0 3.2e-143 477.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SEC-C PF02810.13 001108687.1_45728001_3 - 1.3 8.9 6.4 3.5 7.5 6.4 1.8 1 0 0 1 1 1 0 SEC-C motif Kelch_3 PF13415.4 001108691.1_45726001_2 - 3.6e-22 78.0 14.6 1.5e-08 34.6 0.1 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.4 001108691.1_45726001_2 - 3.7e-20 71.5 0.8 1.1e-07 31.6 0.1 4.5 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.4 001108691.1_45726001_2 - 1.2e-19 69.7 1.2 3.1e-07 30.1 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.13 001108691.1_45726001_2 - 3.2e-16 58.4 4.9 8.3e-08 31.8 0.4 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.23 001108691.1_45726001_2 - 1.1e-14 53.6 2.2 9.3e-06 25.0 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.4 001108691.1_45726001_2 - 1.6e-14 53.4 6.3 0.00042 20.4 0.1 4.2 3 1 1 4 4 4 3 Kelch motif F-box-like PF12937.5 001108691.1_45726001_2 - 1.6e-09 37.3 0.0 5.1e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001108691.1_45726001_2 - 2e-07 30.5 0.0 4.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain PseudoU_synth_1 PF01416.18 001108699.1_45724001_2 - 1.8e-31 108.6 0.0 1.5e-23 83.2 0.0 2.6 3 0 0 3 3 3 2 tRNA pseudouridine synthase Lys PF00062.18 001108746.1_45723001_1 - 2.2e-46 157.0 3.3 3e-46 156.6 3.3 1.2 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family DUF4723 PF15851.3 001108758.1_45721001_2 - 0.87 9.6 9.3 1.5 8.9 9.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4723) C1_1 PF00130.20 001108758.1_45721001_2 - 4.1 7.2 12.3 0.14 11.9 4.7 2.2 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) cwf18 PF08315.10 001108783.1_45722001_2 - 5.5e-38 130.5 19.1 6.9e-38 130.2 19.1 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Arg_tRNA_synt_N PF03485.14 001108783.1_45722001_2 - 0.059 13.8 0.7 0.096 13.1 0.7 1.3 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain Spore_III_AB PF09548.8 001108783.1_45722001_2 - 0.068 13.1 0.5 0.74 9.8 0.1 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) F-box PF00646.31 001108804.1_45722001_3 - 9.9e-10 37.9 0.5 1.9e-09 37.1 0.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001108804.1_45722001_3 - 5.8e-08 32.4 0.3 1.3e-07 31.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.3 001108804.1_45722001_3 - 0.015 15.0 0.1 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 F-box Elongin_A PF06881.9 001108804.1_45722001_3 - 0.071 13.5 0.9 0.11 12.8 0.9 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Peptidase_M8 PF01457.14 001108843.1_45729001_1 - 1.2e-60 205.6 4.2 2.3e-58 198.1 2.1 3.0 2 1 0 2 2 2 2 Leishmanolysin NACHT PF05729.10 001172164.2_45727001_2 - 3.1e-37 127.9 0.6 8e-37 126.6 0.1 2.0 2 0 0 2 2 2 1 NACHT domain PYRIN PF02758.14 001172164.2_45727001_2 - 6.8e-27 93.3 7.1 4.6e-26 90.7 7.1 2.6 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain LRR_6 PF13516.4 001172164.2_45727001_2 - 2.7e-12 45.6 28.4 5.9e-05 22.7 0.2 7.3 7 0 0 7 7 7 3 Leucine Rich repeat AAA_16 PF13191.4 001172164.2_45727001_2 - 0.00059 20.1 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.4 001172164.2_45727001_2 - 0.21 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.5 001172164.2_45727001_2 - 0.48 10.8 26.9 0.7 10.3 3.9 5.3 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001172164.2_45727001_2 - 0.57 9.9 16.1 4.9 6.9 0.2 5.5 5 0 0 5 5 5 0 Leucine rich repeat DUF1104 PF06518.9 001172164.2_45727001_2 - 0.68 10.2 5.4 0.92 9.8 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) LRR_1 PF00560.31 001172164.2_45727001_2 - 1.2 9.7 22.0 1.3 9.6 0.5 6.6 5 1 0 5 5 5 0 Leucine Rich Repeat zf-H2C2_2 PF13465.4 001107500.3_45729001_3 - 2.9e-79 258.1 93.0 6.1e-09 35.8 0.5 12.8 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.24 001107500.3_45729001_3 - 2.6e-37 125.1 102.8 6.3e-05 23.1 2.7 12.3 12 0 0 12 12 12 10 Zinc finger, C2H2 type KRAB PF01352.25 001107500.3_45729001_3 - 3.3e-21 74.6 0.1 5.9e-21 73.7 0.1 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001107500.3_45729001_3 - 2.9e-19 67.9 97.0 0.042 14.6 1.8 12.6 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001107500.3_45729001_3 - 1.6e-05 24.6 66.1 1.3 8.9 0.1 11.9 11 0 0 11 11 11 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001107500.3_45729001_3 - 8.4e-05 22.5 66.8 0.048 13.6 2.8 8.4 4 2 5 9 9 9 8 Zinc ribbon domain Methyltransf_11 PF08241.10 001037355.1_45724001_3 - 1.4e-19 70.3 0.1 2.5e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 001037355.1_45724001_3 - 3.2e-16 59.6 0.0 4.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001037355.1_45724001_3 - 4.9e-13 49.5 0.0 8.1e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001037355.1_45724001_3 - 1.6e-11 44.6 0.0 3.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001037355.1_45724001_3 - 3.1e-11 43.2 0.0 4.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.16 001037355.1_45724001_3 - 3.1e-07 29.8 0.0 4.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.13 001037355.1_45724001_3 - 5e-05 23.1 0.0 9.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase CheR PF01739.16 001037355.1_45724001_3 - 0.026 13.9 0.0 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Baculo_PEP_C PF04513.10 001109124.1_45725001_1 - 0.048 13.6 1.7 0.12 12.3 1.7 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3596 PF12167.6 001109124.1_45725001_1 - 0.15 11.9 0.9 1.4 8.8 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3596) GRP PF07172.9 001037524.1_45721001_2 - 0.19 12.3 0.0 0.25 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycine rich protein family Conotoxin PF02950.15 001037524.1_45721001_2 - 1.3 9.9 8.0 5.3 8.0 8.0 1.8 1 1 0 1 1 1 0 Conotoxin SNF2_N PF00176.21 001106454.3_45729001_2 - 3.1e-74 249.7 0.9 5.9e-73 245.4 0.0 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.29 001106454.3_45729001_2 - 8e-13 48.6 0.0 1.9e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001106454.3_45729001_2 - 2.9e-10 40.3 0.0 7.1e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-GRF PF06839.10 001106454.3_45729001_2 - 8.3e-07 28.9 2.4 8.3e-07 28.9 2.4 2.6 2 0 0 2 2 2 1 GRF zinc finger DEAD PF00270.27 001106454.3_45729001_2 - 8.2e-06 25.6 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.4 001106454.3_45729001_2 - 0.11 11.2 0.0 0.24 10.1 0.0 1.4 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 7tm_1 PF00001.19 001109239.1_45727001_3 - 5.1e-54 183.2 18.0 5.1e-54 183.2 18.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Herpes_US9 PF06072.9 001109239.1_45727001_3 - 0.21 11.4 2.2 0.38 10.5 0.8 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF4657 PF15552.4 001134571.2_45724001_3 - 6.1e-133 442.9 7.7 7.3e-133 442.6 7.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4657) Kelch_1 PF01344.23 001047093.1_45727001_2 - 1.6e-85 280.3 14.3 8.4e-18 63.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.4 001047093.1_45727001_2 - 4.6e-50 166.2 5.3 1.9e-10 40.5 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.13 001047093.1_45727001_2 - 2.4e-32 110.9 0.2 2.4e-32 110.9 0.2 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.13 001047093.1_45727001_2 - 3.1e-32 109.2 7.9 3.2e-07 29.9 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.4 001047093.1_45727001_2 - 7.9e-29 99.2 10.4 3.5e-07 29.9 0.0 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB PF00651.29 001047093.1_45727001_2 - 1.3e-28 99.3 0.3 2.1e-28 98.6 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.4 001047093.1_45727001_2 - 6.5e-20 70.8 11.0 2.1e-06 27.7 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.4 001047093.1_45727001_2 - 1.5e-07 31.1 2.6 0.15 11.9 0.0 5.9 6 0 0 6 6 6 2 Kelch motif Glu_cyclase_2 PF05096.10 001047093.1_45727001_2 - 0.012 14.9 0.0 1.4 8.2 0.0 2.5 1 1 2 3 3 3 0 Glutamine cyclotransferase Pet191_N PF10203.7 001047093.1_45727001_2 - 5.8 7.2 7.3 11 6.3 2.2 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 PMP22_Claudin PF00822.18 133540.1_45722001_1 - 3.6e-10 39.8 6.2 7.6e-09 35.5 6.2 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 133540.1_45722001_1 - 0.0029 17.3 14.6 0.14 11.7 8.1 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction BPD_transp_2 PF02653.14 133540.1_45722001_1 - 0.01 14.9 5.4 0.014 14.5 5.4 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Claudin_3 PF06653.9 133540.1_45722001_1 - 0.017 14.9 8.3 0.034 13.9 8.3 1.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like NUDIX PF00293.26 001109340.1_45723001_3 - 1.5e-18 67.0 0.0 2.3e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ABC_trans_CmpB PF06541.9 001109359.1_45728001_3 - 3.6e-08 33.6 11.0 3.6e-08 33.6 11.0 1.8 2 0 0 2 2 2 1 Putative ABC-transporter type IV FAM163 PF15069.4 001109458.1_45723001_1 - 5.7e-62 208.8 0.0 7.8e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 FAM163 family DUF4006 PF13179.4 001109458.1_45723001_1 - 0.047 13.5 1.3 0.083 12.7 1.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Acylphosphatase PF00708.16 001199167.1_45722001_1 - 4.6e-22 78.1 0.3 6.5e-22 77.6 0.3 1.2 1 0 0 1 1 1 1 Acylphosphatase LCE PF14672.4 001109500.1_45722001_2 - 2.4e-09 37.6 75.5 2.4e-09 37.6 75.5 6.4 1 1 3 4 4 4 1 Late cornified envelope Peptidase_M56 PF05569.9 001109500.1_45722001_3 - 1 8.3 13.2 4.2 6.3 0.0 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 LMF1 PF06762.12 001109500.1_45722001_3 - 2.9 6.7 4.5 3.4 6.5 4.5 1.1 1 0 0 1 1 1 0 Lipase maturation factor zf-DNL PF05180.10 024073.1_45722120_1 - 3.6e-26 90.7 0.1 5.5e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 DNL zinc finger DUF2465 PF10239.7 037147.1_45723120_1 - 2.3e-89 299.7 0.0 1.8e-88 296.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2465) WD40 PF00400.30 073588.1_45725120_1 - 3.8e-08 33.7 2.7 20 6.1 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 073588.1_45725120_1 - 0.00052 20.1 0.1 2.8 8.2 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CENP-H PF05837.10 026689.1_45721120_3 - 0.033 14.5 5.8 0.04 14.2 5.8 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Bcr-Abl_Oligo PF09036.8 026689.1_45721120_3 - 0.037 13.9 2.3 0.047 13.6 1.2 1.7 1 1 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain APG6 PF04111.10 026689.1_45721120_3 - 0.048 12.9 4.5 0.055 12.7 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.11 026689.1_45721120_3 - 0.12 12.9 1.4 0.15 12.6 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.13 026689.1_45721120_3 - 0.75 9.5 8.5 0.22 11.2 5.2 1.7 1 1 1 2 2 2 0 Septum formation initiator Ribosomal_L37ae PF01780.17 027983.1_45722120_2 - 7.4e-13 48.3 3.0 1.2e-12 47.6 3.0 1.2 1 0 0 1 1 1 1 Ribosomal L37ae protein family MAP2_projctn PF08377.8 029398.1_45721120_1 - 0.17 9.8 0.1 0.19 9.6 0.1 1.0 1 0 0 1 1 1 0 MAP2/Tau projection domain Toxin_33 PF08121.9 027235.1_45727120_1 - 0.17 11.6 4.0 0.7 9.6 4.0 2.1 1 0 0 1 1 1 0 Waglerin family zf-C2H2 PF00096.24 027235.1_45727120_3 - 1.6e-21 75.4 52.7 1.7e-06 28.0 0.6 7.0 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 027235.1_45727120_3 - 1.3e-13 50.4 49.3 0.0011 19.4 1.0 6.7 7 0 0 7 7 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.4 027235.1_45727120_3 - 3.8e-13 49.1 48.1 2.2e-06 27.7 1.2 7.9 9 0 0 9 9 8 5 Zinc-finger double domain zf-C2H2_11 PF16622.3 027235.1_45727120_3 - 1.2e-06 28.0 30.6 0.0012 18.4 0.6 5.9 6 0 0 6 6 6 4 zinc-finger C2H2-type CpXC PF14353.4 027235.1_45727120_3 - 0.00014 21.7 14.7 0.0054 16.6 0.8 4.9 3 2 0 3 3 3 1 CpXC protein zf-C2H2_6 PF13912.4 027235.1_45727120_3 - 0.00015 21.5 28.6 0.017 14.9 0.8 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.5 027235.1_45727120_3 - 0.00069 19.8 1.0 0.00069 19.8 1.0 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 027235.1_45727120_3 - 0.003 17.7 14.4 0.0054 16.9 0.1 4.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding DUF1610 PF07754.9 027235.1_45727120_3 - 0.02 14.7 0.9 0.02 14.7 0.9 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) FYDLN_acid PF09538.8 027235.1_45727120_3 - 0.23 12.0 8.5 3.9 8.1 0.0 4.4 2 1 1 4 4 4 0 Protein of unknown function (FYDLN_acid) ADK_lid PF05191.12 027235.1_45727120_3 - 0.51 10.3 12.8 14 5.7 0.1 4.8 4 1 1 5 5 5 0 Adenylate kinase, active site lid SprT-like PF10263.7 027235.1_45727120_3 - 0.63 9.7 11.8 7.2 6.3 0.2 3.2 1 1 1 3 3 3 0 SprT-like family DUF3268 PF11672.6 027235.1_45727120_3 - 2.7 8.2 5.7 0.68 10.1 0.2 2.5 2 1 2 4 4 4 0 zinc-finger-containing domain Terminase_GpA PF05876.10 027235.1_45727120_3 - 8.3 4.7 14.4 0.29 9.6 0.5 2.5 2 1 1 3 3 3 0 Phage terminase large subunit (GpA) DUF4681 PF15732.3 036618.2_45722120_2 - 2.8e-31 108.3 2.4 5.5e-31 107.4 2.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4681) Lectin_C PF00059.19 002706.1_45721120_3 - 0.0055 17.3 0.2 0.0073 16.9 0.2 1.2 1 0 0 1 1 1 1 Lectin C-type domain SRTM1 PF15872.3 001109580.1_45727001_3 - 6.3e-54 180.3 11.7 1.1e-53 179.5 11.7 1.4 1 0 0 1 1 1 1 Serine-rich and transmembrane domain-containing protein 1 DUF4531 PF15041.4 001109605.1_45722001_3 - 1.5e-95 318.5 10.4 1.7e-95 318.3 10.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4531) LRR_8 PF13855.4 001109609.1_45724001_3 - 5.4e-68 224.5 43.8 1.2e-16 60.1 1.2 6.5 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.5 001109609.1_45724001_3 - 1.2e-20 73.0 24.7 2.2e-05 24.6 1.5 7.0 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) I-set PF07679.14 001109609.1_45724001_3 - 2.3e-16 59.5 0.0 3.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 001109609.1_45724001_3 - 1.8e-15 57.2 0.1 5.1e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain LRR_5 PF13306.4 001109609.1_45724001_3 - 2.2e-10 40.5 0.0 0.00035 20.4 0.0 2.5 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) ig PF00047.23 001109609.1_45724001_3 - 1.1e-09 38.1 0.0 2.9e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001109609.1_45724001_3 - 3.7e-08 33.5 0.0 8.9e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.31 001109609.1_45724001_3 - 1.2e-07 31.1 25.7 7.9 7.3 0.0 10.8 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_9 PF14580.4 001109609.1_45724001_3 - 1.5e-05 24.5 8.0 0.17 11.3 0.3 3.7 1 1 3 4 4 4 3 Leucine-rich repeat LRRNT PF01462.16 001109609.1_45724001_3 - 0.00019 20.8 2.0 0.00019 20.8 2.0 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.4 001109609.1_45724001_3 - 0.00022 20.9 25.8 0.33 11.0 0.1 9.0 10 0 0 10 10 10 2 Leucine Rich repeat V-set PF07686.15 001109609.1_45724001_3 - 0.00045 20.2 0.1 0.0044 17.0 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain DUF1049 PF06305.9 001109609.1_45724001_3 - 0.14 11.8 0.2 0.3 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Sp38 PF07354.10 001109609.1_45724001_3 - 0.16 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) LRR_4 PF12799.5 001109617.1_45726001_2 - 2 8.8 12.1 5.2 7.5 0.0 4.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) SCA7 PF08313.10 001109634.1_45722001_2 - 0.034 13.9 2.7 0.054 13.3 2.7 1.3 1 0 0 1 1 1 0 SCA7, zinc-binding domain UPAR_LY6 PF00021.19 001109634.1_45722001_3 - 0.033 14.7 6.9 0.044 14.3 6.9 1.2 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Carb_anhydrase PF00194.19 001105901.1_45723001_2 - 7.6e-86 287.6 0.0 8.8e-86 287.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase ACTH_domain PF00976.16 001105901.1_45723001_2 - 2.9 7.8 5.0 6.2 6.7 5.0 1.5 1 0 0 1 1 1 0 Corticotropin ACTH domain Crystall PF00030.17 001106573.1_45721001_2 - 6.1e-34 115.9 0.3 1.2e-28 99.0 0.3 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001106573.1_45721001_2 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor family I36 PDZ PF00595.22 001108107.2_45727001_3 - 1.1e-19 70.4 0.2 1.3e-14 54.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001108107.2_45727001_3 - 2.5e-07 30.8 0.1 1.1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 PDZ domain BAH PF01426.16 001107123.1_45729001_1 - 1.5e-09 37.6 0.0 9.6e-09 35.0 0.0 2.2 1 1 0 1 1 1 1 BAH domain DUF4537 PF15057.4 001107123.1_45729001_1 - 0.00018 21.4 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) EamA PF00892.18 001191886.1_45723001_3 - 1.3 9.1 13.0 3 7.9 13.0 1.5 1 1 0 1 1 1 0 EamA-like transporter family zf-H2C2_2 PF13465.4 153731.1_45726001_3 - 3.8e-117 377.8 173.3 2.2e-08 34.0 0.8 19.3 21 0 0 21 21 19 18 Zinc-finger double domain zf-C2H2 PF00096.24 153731.1_45726001_3 - 2.5e-64 210.2 177.0 3.6e-05 23.9 0.9 20.5 20 0 0 20 20 20 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 153731.1_45726001_3 - 1.2e-53 175.0 166.1 0.0014 19.2 0.9 20.4 20 0 0 20 20 20 18 C2H2-type zinc finger zf-C2H2_6 PF13912.4 153731.1_45726001_3 - 1.3e-32 111.0 136.3 1.9e-05 24.4 2.8 18.9 19 0 0 19 19 19 16 C2H2-type zinc finger KRAB PF01352.25 153731.1_45726001_3 - 4.1e-21 74.2 0.0 1.1e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 153731.1_45726001_3 - 5.1e-18 64.8 97.5 0.025 14.8 0.1 18.5 19 0 0 19 19 19 8 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.4 153731.1_45726001_3 - 2.8e-10 39.8 83.0 1.4 8.8 0.1 16.9 15 3 2 17 17 17 9 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.8 153731.1_45726001_3 - 5e-10 39.2 108.9 0.022 14.8 4.3 15.1 7 5 9 16 16 16 13 Zinc ribbon domain zf-C2H2_11 PF16622.3 153731.1_45726001_3 - 0.00018 21.1 121.8 0.00042 19.9 0.5 17.2 18 0 0 18 18 18 7 zinc-finger C2H2-type C1_4 PF07975.10 153731.1_45726001_3 - 0.0024 18.0 1.6 0.0024 18.0 1.6 12.2 3 2 12 16 16 15 1 TFIIH C1-like domain DUF3268 PF11672.6 153731.1_45726001_3 - 0.015 15.5 75.4 0.9 9.8 0.7 9.5 7 3 1 9 9 9 0 zinc-finger-containing domain VPS9 PF02204.16 153731.1_45726001_3 - 0.11 12.6 0.7 19 5.4 0.0 3.3 2 2 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain BolA PF01722.16 153731.1_45726001_3 - 0.2 11.8 20.1 0.33 11.1 0.4 6.3 6 1 2 8 8 8 0 BolA-like protein zf-met PF12874.5 153731.1_45726001_3 - 3.2 8.1 120.0 0.18 12.1 0.4 16.1 16 0 0 16 16 16 0 Zinc-finger of C2H2 type 7tm_1 PF00001.19 181364.4_45723001_3 - 1e-53 182.2 5.5 1.2e-53 181.9 5.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 181364.4_45723001_3 - 1.3e-12 47.9 5.1 1e-11 45.0 1.5 2.1 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.7 181364.4_45723001_3 - 5.3e-12 45.5 3.2 9.7e-12 44.7 3.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 181364.4_45723001_3 - 1.5e-05 24.4 5.1 1.5e-05 24.4 5.1 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.7 181364.4_45723001_3 - 2.7e-05 23.5 6.5 0.023 13.9 0.0 2.8 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.7 181364.4_45723001_3 - 0.00093 18.5 5.1 0.0019 17.5 5.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.11 181364.4_45723001_3 - 0.017 14.1 4.2 0.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Taste receptor protein (TAS2R) 4F5 PF04419.12 001098782.1_45725001_3 - 5.9e-10 39.7 10.8 5.9e-10 39.7 10.8 2.9 3 0 0 3 3 3 1 4F5 protein family DHR-2 PF06920.11 001108997.1_45729001_2 - 6.1e-18 64.6 0.0 7.9e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Dock homology region 2 DHR-2 PF06920.11 001108997.1_45729001_3 - 3e-178 593.6 1.5 2.5e-94 316.7 0.2 2.3 2 0 0 2 2 2 2 Dock homology region 2 DOCK-C2 PF14429.4 001108997.1_45729001_3 - 2.3e-47 161.2 0.0 3.9e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.6 001108997.1_45729001_3 - 6.8e-25 87.1 0.1 2.5e-24 85.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) DOCK_N PF16172.3 001108997.1_45729001_3 - 0.063 12.0 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 DOCK N-terminus 5_nucleotid PF05761.12 001106393.1_45726001_1 - 7.8e-56 189.7 0.0 1.1e-55 189.2 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family Hydrolase_like PF13242.4 001106393.1_45726001_1 - 0.0058 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Fucokinase PF07959.10 199494.1_45724001_1 - 1.2e-137 459.0 0.2 1.5e-137 458.8 0.2 1.1 1 0 0 1 1 1 1 L-fucokinase Hexapep PF00132.22 199494.1_45724001_1 - 0.16 11.6 3.3 0.31 10.7 0.7 2.6 2 1 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Arf PF00025.19 212459.1_45722001_1 - 4.7e-37 127.0 0.0 6.1e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.20 212459.1_45722001_1 - 1.8e-10 40.5 0.0 2.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 212459.1_45722001_1 - 2.8e-10 40.3 0.0 4.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.8 212459.1_45722001_1 - 6.1e-09 35.4 0.0 7.7e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 212459.1_45722001_1 - 0.00018 20.8 0.0 0.00033 19.9 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 212459.1_45722001_1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.18 212459.1_45722001_1 - 0.087 11.8 0.1 2.2 7.2 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.4 212459.1_45722001_1 - 0.091 12.9 0.0 0.36 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.4 212459.1_45722001_1 - 0.092 13.1 0.0 0.13 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain PPTA PF01239.20 001105760.2_45724001_3 - 8.8e-25 85.6 8.9 4.3e-07 29.3 0.1 6.4 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Lipocalin PF00061.21 001001519.1_45722001_1 - 1.2e-06 28.6 0.0 1.5e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family MHC_I PF00129.16 001008842.1_45723001_1 - 1.7e-89 298.0 1.8 2.2e-89 297.6 1.8 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001008842.1_45723001_1 - 1.9e-16 60.1 0.0 3.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001008842.1_45723001_1 - 4.3e-07 29.6 4.8 4.3e-07 29.6 4.8 2.0 2 0 0 2 2 2 1 MHC_I C-terminus Ig_3 PF13927.4 001008842.1_45723001_1 - 0.00018 21.9 0.2 0.1 13.1 0.0 2.4 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.23 001008842.1_45723001_1 - 0.0023 17.9 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001008842.1_45723001_1 - 0.0025 17.7 0.1 0.0058 16.6 0.0 1.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Marek_A PF02124.13 001008842.1_45723001_1 - 0.055 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Marek's disease glycoprotein A MHC_I PF00129.16 001008849.1_45723001_1 - 1.8e-48 164.4 0.1 2.4e-48 163.9 0.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001008849.1_45723001_1 - 1e-16 61.0 0.0 2.9e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001008849.1_45723001_1 - 1.1e-05 25.8 0.3 0.039 14.4 0.0 2.5 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 001008849.1_45723001_1 - 0.00037 20.4 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001008849.1_45723001_1 - 0.0022 18.0 0.0 0.0056 16.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain MHC_I_3 PF16497.3 001008849.1_45723001_1 - 0.0045 16.4 0.2 0.0068 15.8 0.2 1.3 1 0 0 1 1 1 1 MHC-I family domain DUF4448 PF14610.4 001008849.1_45723001_1 - 0.072 12.7 0.8 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF3377 PF11857.6 001008849.1_45723001_1 - 0.11 12.3 3.8 13 5.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) NPDC1 PF06809.9 001004231.1_45723001_2 - 9e-198 656.1 19.8 1.6e-197 655.3 19.8 1.4 1 1 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) tRNA_int_endo PF01974.15 001006968.1_45723001_2 - 4.5e-21 74.6 0.0 8.4e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain IMD PF08397.9 001134201.1_43529001_3 - 4.8e-106 352.9 4.2 6.2e-106 352.6 4.2 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain WH2 PF02205.18 001134201.1_43529001_3 - 5.1e-07 29.2 0.1 1.2e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 WH2 motif OmpH PF03938.12 001134201.1_43529001_3 - 6.6 6.6 9.9 12 5.7 9.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Corona_M PF01635.16 131067.1_45722120_3 - 0.017 14.3 0.5 0.022 13.9 0.5 1.1 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Gp_dh_C PF02800.18 003722.1_45723120_1 - 3.1e-45 153.5 0.0 4.5e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.22 003722.1_45723120_3 - 7.1e-34 116.0 0.1 9.8e-34 115.6 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PTB PF08416.11 001106463.1_45726001_1 - 2.7e-37 127.7 0.2 4.3e-37 127.1 0.2 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.26 001106463.1_45726001_1 - 4.5e-11 42.0 0.0 1.1e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 001106463.1_45726001_1 - 5.7e-09 35.6 0.1 1.7e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.15 001106463.1_45726001_1 - 4.2e-05 23.0 0.0 7.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.9 001106463.1_45726001_1 - 0.0008 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain hSH3 PF14603.4 001106463.1_45726001_1 - 0.026 14.9 0.2 0.073 13.5 0.0 1.8 2 0 0 2 2 2 0 Helically-extended SH3 domain 7tm_4 PF13853.4 001000174.1_45722001_1 - 5.3e-97 324.7 21.5 6.4e-97 324.5 21.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000174.1_45722001_1 - 1.9e-15 56.7 21.3 1.7e-14 53.6 21.3 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000174.1_45722001_1 - 3e-07 29.9 19.4 5.3e-07 29.1 18.8 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx CNH PF00780.20 001329948.1_39729001_1 - 2.9e-61 207.4 0.0 6e-61 206.3 0.0 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.23 001329948.1_39729001_1 - 4.4e-59 199.9 0.8 3.6e-58 196.9 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001329948.1_39729001_1 - 4.1e-27 95.0 0.0 1.1e-26 93.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.27 001329948.1_39729001_1 - 1.9e-10 41.0 0.0 5.5e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 PH domain C1_1 PF00130.20 001329948.1_39729001_1 - 3.2e-05 23.6 9.2 7.2e-05 22.5 9.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.22 001329948.1_39729001_1 - 0.002 18.7 1.0 0.0066 17.0 1.0 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.9 001329948.1_39729001_1 - 0.0036 16.3 0.1 0.0098 14.8 0.1 1.7 1 0 0 1 1 1 1 Seadornavirus VP7 DNA_methylase PF00145.15 001032355.1_49829001_1 - 3.6e-49 167.8 1.9 2.7e-48 164.9 0.0 2.8 2 2 1 3 3 3 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.6 001032355.1_49829001_1 - 4.2e-46 156.4 0.0 3.3e-45 153.5 0.0 2.3 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.16 001032355.1_49829001_1 - 2e-42 143.7 0.0 3.7e-20 71.8 0.0 2.7 2 0 0 2 2 2 2 BAH domain DMAP_binding PF06464.9 001032355.1_49829001_1 - 4.3e-20 72.4 2.8 4.3e-20 72.4 2.8 2.7 2 1 1 3 3 3 1 DMAP1-binding Domain zf-CXXC PF02008.18 001032355.1_49829001_1 - 4.6e-15 55.2 21.5 1.7e-14 53.4 21.5 2.1 1 0 0 1 1 1 1 CXXC zinc finger domain PA26 PF04636.11 001032355.1_49829001_1 - 4.2 6.1 4.6 8.2 5.1 4.6 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3553 PF12073.6 001009473.1_39529001_2 - 0.091 12.4 1.1 0.2 11.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) DNA_methylase PF00145.15 001009473.1_39529001_3 - 3.8e-48 164.4 0.0 3.8e-48 164.4 0.0 3.2 2 2 1 3 3 3 1 C-5 cytosine-specific DNA methylase BAH PF01426.16 001009473.1_39529001_3 - 2.8e-46 156.2 0.0 6.6e-22 77.5 0.1 2.8 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.6 001009473.1_39529001_3 - 5.8e-46 156.0 0.0 4.2e-45 153.2 0.0 2.3 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain DMAP_binding PF06464.9 001009473.1_39529001_3 - 1.5e-21 77.2 2.2 1.5e-21 77.2 2.2 2.7 2 0 0 2 2 2 1 DMAP1-binding Domain zf-CXXC PF02008.18 001009473.1_39529001_3 - 5.6e-14 51.8 17.7 5.6e-14 51.8 17.7 2.7 2 0 0 2 2 2 1 CXXC zinc finger domain HTH_24 PF13412.4 001009473.1_39529001_3 - 0.035 13.5 0.2 0.22 11.0 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_12 PF08461.8 001009473.1_39529001_3 - 0.56 10.1 3.0 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain PA26 PF04636.11 001009473.1_39529001_3 - 1.7 7.4 7.1 3.3 6.4 7.1 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PMP22_Claudin PF00822.18 001173039.1_09922001_2 - 1.9e-40 138.3 17.2 2.2e-40 138.1 17.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001173039.1_09922001_2 - 1.5e-10 41.1 21.1 5.2e-05 22.9 0.4 2.2 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Phage_holin_3_6 PF07332.9 001173039.1_09922001_2 - 0.31 11.0 16.2 0.2 11.6 1.8 2.2 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III COPI_assoc PF08507.8 001173039.1_09922001_2 - 0.46 10.5 16.9 9.8 6.2 0.4 3.0 2 1 0 2 2 2 0 COPI associated protein DUF373 PF04123.11 001173039.1_09922001_2 - 0.68 9.2 7.0 1.1 8.4 6.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF2070 PF09843.7 001173039.1_09922001_2 - 0.78 7.8 5.5 0.89 7.6 5.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Zip PF02535.20 001173039.1_09922001_2 - 0.91 8.5 5.9 1 8.4 5.3 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter DUF3810 PF12725.5 001173039.1_09922001_2 - 4.3 6.4 6.7 6 6.0 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) IGF2_C PF08365.9 001169030.1_40422001_1 - 1.9e-28 98.1 3.2 3.1e-28 97.4 3.2 1.3 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Insulin PF00049.16 001169030.1_40422001_1 - 1.9e-14 54.3 5.2 7.1e-07 30.0 2.3 2.4 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family Integrin_beta PF00362.16 001246669.1_49826001_3 - 4.8e-108 360.4 0.0 6.8e-108 359.9 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.10 001246669.1_49826001_3 - 2.2e-18 66.4 6.0 2.2e-18 66.4 6.0 4.3 3 1 0 4 4 4 1 Integrin beta tail domain Integrin_b_cyt PF08725.9 001246669.1_49826001_3 - 7.2e-18 63.9 0.2 1.3e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain PSI_integrin PF17205.1 001246669.1_49826001_3 - 1e-13 50.7 6.2 1e-13 50.7 6.2 4.5 3 1 1 4 4 4 1 Integrin plexin domain EGF_2 PF07974.11 001246669.1_49826001_3 - 3.3e-12 46.4 87.5 0.0004 20.5 16.4 5.8 4 2 1 5 5 5 4 EGF-like domain DUF2975 PF11188.6 001246669.1_49826001_3 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Menin PF05053.11 001169000.1_40424001_1 - 1.2e-275 916.1 0.0 5.5e-250 831.3 0.0 2.1 2 0 0 2 2 2 2 Menin Peptidase_C14 PF00656.20 001286089.1_09022001_1 - 2.1e-52 178.4 0.2 2.6e-52 178.1 0.2 1.1 1 0 0 1 1 1 1 Caspase domain PUF PF00806.17 001286089.1_09022001_1 - 0.063 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat PH_13 PF16652.3 001169044.1_40429001_1 - 2.2e-73 245.2 0.1 2.2e-73 245.2 0.1 4.0 3 1 2 5 5 3 1 Pleckstrin homology domain SH3_9 PF14604.4 001169044.1_40429001_1 - 1.5e-67 223.1 10.3 2e-16 59.4 0.1 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.26 001169044.1_40429001_1 - 7.6e-61 201.4 16.4 1.1e-16 60.0 0.3 5.6 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.15 001169044.1_40429001_1 - 1.8e-57 190.7 4.5 3.9e-14 51.9 0.0 5.6 5 0 0 5 5 5 5 Variant SH3 domain INTAP PF16617.3 001169044.1_40429001_1 - 2e-55 186.1 14.6 6.5e-55 184.4 12.8 2.5 2 0 0 2 2 2 1 Intersectin and clathrin adaptor AP2 binding region RhoGEF PF00621.18 001169044.1_40429001_1 - 3.8e-46 157.5 1.6 3.8e-46 157.5 1.6 3.0 3 0 0 3 3 2 1 RhoGEF domain EF-hand_4 PF12763.5 001169044.1_40429001_1 - 9.2e-31 105.7 0.0 8.2e-15 54.5 0.0 3.0 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.28 001169044.1_40429001_1 - 2.5e-21 75.8 0.0 6.4e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.30 001169044.1_40429001_1 - 4.2e-09 35.2 0.0 0.0022 17.3 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.4 001169044.1_40429001_1 - 9.9e-07 28.1 0.1 0.25 11.3 0.0 4.3 4 0 0 4 4 3 2 EF-hand domain EF-hand_7 PF13499.4 001169044.1_40429001_1 - 5.5e-05 23.4 0.0 0.023 15.0 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair PH PF00169.27 001169044.1_40429001_1 - 0.0004 20.7 0.0 0.0015 18.9 0.0 2.0 1 0 0 1 1 1 1 PH domain EF-hand_5 PF13202.4 001169044.1_40429001_1 - 0.0096 15.3 0.2 0.59 9.6 0.0 2.8 2 0 0 2 2 2 1 EF hand GSH_synthase PF03199.13 001169044.1_40429001_1 - 0.018 15.4 0.8 0.12 12.7 0.1 3.0 2 1 0 2 2 2 0 Eukaryotic glutathione synthase EF-hand_8 PF13833.4 001169044.1_40429001_1 - 0.084 12.5 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair IGF2_C PF08365.9 001287042.1_09023001_3 - 1.6e-25 88.7 1.9 3.3e-25 87.7 1.9 1.6 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Insulin PF00049.16 001287042.1_09023001_3 - 2e-13 51.0 5.4 1.7e-06 28.8 2.0 2.5 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family Defensin_2 PF01097.16 001243417.1_49825001_2 - 0.11 12.3 0.2 0.41 10.5 0.2 2.0 1 0 0 1 1 1 0 Arthropod defensin NOT2_3_5 PF04153.16 001243417.1_49825001_3 - 8.8e-31 106.6 0.2 2e-30 105.4 0.2 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Ig_3 PF13927.4 001169062.1_40422001_1 - 4.4e-05 23.9 0.0 7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001169062.1_40422001_1 - 0.00038 20.6 0.0 0.00055 20.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001169062.1_40422001_1 - 0.00086 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.5 001243902.1_49823001_1 - 5.9e-37 124.8 38.7 1.7e-08 34.4 1.1 6.7 3 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001243902.1_49823001_1 - 3.1e-28 98.3 22.2 1.7e-11 43.8 0.5 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.4 001243902.1_49823001_1 - 3.9e-22 77.6 38.3 3.9e-07 29.6 8.5 6.0 1 1 3 6 6 6 6 Leucine rich repeat LRR_6 PF13516.4 001243902.1_49823001_1 - 0.01 15.7 25.3 8.5 6.6 0.1 8.2 9 1 1 10 10 10 0 Leucine Rich repeat LRR_1 PF00560.31 001243902.1_49823001_1 - 0.024 14.9 29.2 1 10.0 0.5 9.1 8 2 0 8 8 8 0 Leucine Rich Repeat IL6Ra-bind PF09240.8 001257236.1_08023001_3 - 6.9e-30 103.2 0.1 1.3e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.15 001257236.1_08023001_3 - 1.9e-08 34.0 1.4 0.00095 18.8 0.0 3.5 3 0 0 3 3 3 3 Tissue factor fn3 PF00041.19 001257236.1_08023001_3 - 0.0045 17.2 0.2 3 8.1 0.1 2.9 2 1 0 2 2 2 2 Fibronectin type III domain EpoR_lig-bind PF09067.8 001257236.1_08023001_3 - 0.12 12.4 1.8 0.36 10.9 0.9 2.1 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding His_Phos_1 PF00300.20 001134968.1_49822001_1 - 2.1e-34 118.8 0.1 3.2e-27 95.4 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Filament PF00038.19 001173038.1_09925001_3 - 1.2e-15 57.8 31.4 6.4e-12 45.5 9.0 2.1 1 1 1 2 2 2 2 Intermediate filament protein LemA PF04011.10 001173038.1_09925001_3 - 0.0085 15.5 1.0 0.021 14.2 1.0 1.7 1 0 0 1 1 1 1 LemA family Prefoldin PF02996.15 001173038.1_09925001_3 - 0.18 11.6 11.6 0.51 10.1 1.0 3.3 2 1 1 3 3 3 0 Prefoldin subunit DUF1664 PF07889.10 001173038.1_09925001_3 - 0.31 10.9 3.7 0.62 9.9 2.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) RTBV_P46 PF06216.9 001173038.1_09925001_3 - 0.41 9.3 1.4 0.64 8.7 1.4 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Spc7 PF08317.9 001173038.1_09925001_3 - 0.68 8.6 27.4 0.011 14.6 12.1 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.10 001173038.1_09925001_3 - 3.1 7.7 28.8 0.17 11.8 11.2 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.10 001173038.1_09925001_3 - 3.1 7.0 21.5 16 4.6 0.2 2.9 1 1 0 2 2 2 0 Autophagy protein Apg6 DIT1_PvcA PF05141.10 001173038.1_09925001_3 - 3.5 6.9 4.8 2.8 7.2 2.7 1.8 1 1 1 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Baculo_PEP_C PF04513.10 001173038.1_09925001_3 - 3.9 7.4 7.6 0.35 10.8 1.2 2.5 3 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.9 001173038.1_09925001_3 - 4.7 6.9 15.8 1.8 8.2 3.1 2.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 AAA_13 PF13166.4 001173038.1_09925001_3 - 5.1 5.5 12.1 7.4 5.0 12.1 1.2 1 0 0 1 1 1 0 AAA domain COG2 PF06148.9 001173038.1_09925001_3 - 5.3 7.0 7.5 22 5.0 1.1 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.10 001173038.1_09925001_3 - 6.2 7.2 5.8 5.3 7.5 1.4 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.4 001173038.1_09925001_3 - 7 5.8 24.0 0.03 13.5 6.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) FadA PF09403.8 001173038.1_09925001_3 - 7.4 6.9 10.7 1.1 9.7 3.8 2.5 2 0 0 2 2 2 0 Adhesion protein FadA V_ATPase_I PF01496.17 001173038.1_09925001_3 - 8.4 4.0 11.7 20 2.8 11.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family EF-hand_1 PF00036.30 001244184.1_49824001_1 - 1.9e-19 67.5 15.0 0.0001 21.5 0.1 6.1 7 0 0 7 7 7 5 EF hand EF-hand_7 PF13499.4 001244184.1_49824001_1 - 2.1e-17 63.2 15.9 9.2e-06 25.9 0.3 4.1 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001244184.1_49824001_1 - 1.2e-14 52.8 7.1 0.0069 16.1 0.1 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.4 001244184.1_49824001_1 - 1.3e-13 49.6 9.3 0.0041 16.5 0.1 5.1 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.4 001244184.1_49824001_1 - 1.9e-06 27.4 5.5 0.23 11.2 0.1 5.0 5 0 0 5 5 5 2 EF-hand domain pair Arf PF00025.19 001168927.1_40422001_1 - 1.8e-76 255.3 0.1 2.1e-76 255.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.11 001168927.1_40422001_1 - 1.6e-14 54.0 0.1 2.2e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.8 001168927.1_40422001_1 - 3e-14 52.7 0.0 3.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.20 001168927.1_40422001_1 - 8.5e-13 48.1 0.0 9.7e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.18 001168927.1_40422001_1 - 1.1e-12 47.7 1.4 6e-09 35.4 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.10 001168927.1_40422001_1 - 2.7e-11 43.1 0.0 3.2e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001168927.1_40422001_1 - 3.6e-05 23.7 0.0 5.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.16 001168927.1_40422001_1 - 0.0073 15.5 0.2 0.015 14.5 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CbiA PF01656.21 001168927.1_40422001_1 - 0.18 11.7 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NADH_dh_m_C1 PF15088.4 001097470.2_49821001_1 - 1e-31 108.1 0.1 1.7e-31 107.4 0.1 1.4 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial zn-ribbon_14 PF16503.3 001097470.2_49821001_2 - 0.00075 18.8 4.3 0.027 13.8 0.2 2.3 2 0 0 2 2 2 2 Zinc-ribbon Tfb2 PF03849.12 001123120.1_49823001_1 - 1.3e-136 455.1 0.0 1.7e-136 454.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.4 001123120.1_49823001_1 - 8.5e-06 25.8 0.1 6.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Clat_adaptor_s PF01217.18 001244452.1_49822001_3 - 1.2e-61 206.6 8.5 1.4e-61 206.4 8.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPA_C PF08784.9 001244942.1_49824001_3 - 9.3e-25 87.2 0.0 1.9e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.23 001244942.1_49824001_3 - 7.4e-05 22.5 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MarR_2 PF12802.5 001244942.1_49824001_3 - 0.1 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 MarR family Globin PF00042.20 001168815.1_40421001_1 - 1.3e-22 80.3 0.0 1.7e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Globin SBF PF01758.14 001168806.1_40423001_1 - 1.7e-43 148.5 17.0 1.7e-43 148.5 17.0 1.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family IL6Ra-bind PF09240.8 001173125.1_09926001_2 - 4e-28 97.6 1.5 7.1e-28 96.8 0.4 2.0 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.15 001173125.1_09926001_2 - 0.00068 19.3 8.2 0.13 11.9 0.1 3.5 3 0 0 3 3 3 2 Tissue factor EpoR_lig-bind PF09067.8 001173125.1_09926001_2 - 0.11 12.5 4.1 0.07 13.2 0.5 2.4 3 0 0 3 3 3 0 Erythropoietin receptor, ligand binding bZIP_2 PF07716.13 001287231.1_09022001_1 - 4.8e-05 23.2 10.4 8.1e-05 22.5 10.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper GAS PF13851.4 001287231.1_09022001_1 - 0.00087 18.6 6.7 0.0015 17.8 6.7 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.19 001287231.1_09022001_1 - 0.0015 18.5 11.3 0.0024 17.8 11.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.13 001287231.1_09022001_1 - 0.017 14.7 6.3 0.033 13.8 6.3 1.4 1 0 0 1 1 1 0 Septum formation initiator CLZ PF16526.3 001287231.1_09022001_1 - 0.058 13.6 6.9 0.11 12.7 6.9 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MAJIN PF15077.4 001287231.1_09022001_1 - 0.19 11.5 5.5 0.26 11.0 5.5 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein C_Hendra PF16821.3 001287231.1_09022001_1 - 0.48 10.2 6.3 0.87 9.3 6.3 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses IncA PF04156.12 001287231.1_09022001_1 - 0.63 9.7 9.4 0.36 10.4 7.1 1.6 2 0 0 2 2 2 0 IncA protein Neur_chan_memb PF02932.14 001287231.1_09022001_1 - 0.75 9.7 2.5 0.86 9.5 2.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APG6 PF04111.10 001287231.1_09022001_1 - 0.83 8.8 7.7 1.2 8.4 7.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RR_TM4-6 PF06459.10 001287231.1_09022001_1 - 1.1 8.9 7.5 1.4 8.6 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1003 PF06210.9 001287231.1_09022001_1 - 2 8.4 5.0 4 7.5 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) CDC45 PF02724.12 001287231.1_09022001_1 - 2.7 6.1 7.7 2.9 5.9 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF3_subunit PF08597.8 001287231.1_09022001_1 - 8.5 6.1 14.6 16 5.2 14.6 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ubiquitin PF00240.21 001244791.1_49824001_3 - 2.1e-08 33.7 0.0 4.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family BAG PF02179.14 001244791.1_49824001_3 - 1.4e-05 25.2 2.8 2.7e-05 24.3 2.8 1.5 1 0 0 1 1 1 1 BAG domain MutS_III PF05192.16 001244791.1_49824001_3 - 0.059 13.4 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 MutS domain III Amidase PF01425.19 001244791.1_49824001_3 - 0.11 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Amidase YPEB PF14620.4 001244791.1_49824001_3 - 5.2 6.2 6.8 4.5 6.4 0.9 2.0 2 0 0 2 2 2 0 YpeB sporulation Thioredoxin PF00085.18 001168966.1_40424001_1 - 7.4e-69 228.1 0.1 9.3e-34 115.4 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.4 001168966.1_40424001_1 - 1.6e-36 125.9 1.3 3.2e-28 98.8 2.5 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.4 001168966.1_40424001_1 - 2.9e-09 37.2 0.9 0.00056 20.2 0.1 3.7 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001168966.1_40424001_1 - 4e-08 33.3 0.1 0.0027 17.9 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.4 001168966.1_40424001_1 - 2.8e-06 27.3 0.0 0.021 14.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.19 001168966.1_40424001_1 - 4.8e-05 23.1 0.0 0.17 11.6 0.0 2.9 2 0 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.11 001168966.1_40424001_1 - 6.8e-05 22.2 0.0 0.34 10.1 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.4 001168966.1_40424001_1 - 0.00046 20.3 0.2 0.9 9.5 0.0 3.7 3 1 0 4 4 4 1 Thioredoxin Thioredoxin_3 PF13192.4 001168966.1_40424001_1 - 0.021 14.7 0.1 0.65 9.9 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin domain TFIID-31kDa PF02291.13 001285781.1_09923001_1 - 8.2e-51 171.0 0.0 1.2e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001285781.1_09923001_1 - 1.8e-07 31.6 0.2 3.6e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001285781.1_09923001_1 - 2.5e-06 27.7 0.1 4.9e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein AAA_28 PF13521.4 001285781.1_09923001_1 - 1.8e-05 24.9 0.0 2.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Bromo_TP PF07524.11 001285781.1_09923001_1 - 9.3e-05 22.2 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA_17 PF13207.4 001285781.1_09923001_1 - 0.0001 22.6 0.1 0.0001 22.6 0.1 1.8 2 0 0 2 2 1 1 AAA domain Histone PF00125.22 001285781.1_09923001_1 - 0.00029 21.1 0.3 0.00058 20.1 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 AAA PF00004.27 001285781.1_09923001_1 - 0.00051 20.4 0.0 0.00086 19.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CENP-T_C PF15511.4 001285781.1_09923001_1 - 0.0036 17.3 0.1 0.0065 16.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001285781.1_09923001_1 - 0.011 16.0 0.3 0.02 15.2 0.3 1.4 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.13 001285781.1_09923001_1 - 0.014 15.2 0.2 0.022 14.5 0.2 1.3 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.4 001285781.1_09923001_1 - 0.018 15.1 0.5 0.072 13.1 0.5 2.0 1 1 0 1 1 1 0 AAA domain SKI PF01202.20 001285781.1_09923001_1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_22 PF13401.4 001285781.1_09923001_1 - 0.023 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.16 001285781.1_09923001_1 - 0.049 13.2 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.12 001285781.1_09923001_1 - 0.052 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.4 001285781.1_09923001_1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.11 001285781.1_09923001_1 - 0.081 12.1 0.1 0.17 11.1 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_32 PF13654.4 001285781.1_09923001_1 - 0.094 11.3 0.2 0.83 8.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.10 001285781.1_09923001_1 - 0.15 11.2 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ADK PF00406.20 001285781.1_09923001_1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Adenylate kinase Integrin_alpha2 PF08441.10 001035124.1_39528001_2 - 5.1e-39 134.3 0.0 7.3e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.26 001035124.1_39528001_2 - 5.4e-31 108.1 2.4 7.8e-31 107.5 2.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.21 001035124.1_39528001_2 - 8.2e-20 70.5 6.9 1.2e-07 31.6 0.8 3.7 3 0 0 3 3 3 3 FG-GAP repeat VWA_2 PF13519.4 001035124.1_39528001_2 - 5.9e-11 42.9 0.7 2.8e-09 37.5 0.1 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VCBS PF13517.4 001035124.1_39528001_2 - 5e-07 30.1 1.1 0.0002 21.7 0.3 3.4 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001035124.1_39528001_2 - 0.00013 21.6 0.4 0.00029 20.5 0.4 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.4 001035124.1_39528001_2 - 0.0012 18.9 7.1 0.52 10.5 0.0 3.7 4 0 0 4 4 4 2 FG-GAP repeat Not3 PF04065.13 001168874.1_40425001_1 - 4e-95 317.5 27.5 5.3e-95 317.1 27.5 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.16 001168874.1_40425001_1 - 1e-40 138.7 9.6 2.8e-40 137.3 9.6 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ZnuA PF01297.15 001168874.1_40425001_1 - 0.48 9.6 3.7 0.58 9.4 2.7 1.4 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Syntaxin_2 PF14523.4 001168874.1_40425001_1 - 0.76 10.1 8.6 0.18 12.0 1.7 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Swi5 PF07061.9 001168874.1_40425001_1 - 0.97 9.4 8.2 3.4 7.6 0.7 2.7 2 0 0 2 2 2 0 Swi5 DUF4407 PF14362.4 001168874.1_40425001_1 - 2.6 7.2 9.8 4 6.6 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synuclein PF01387.15 001112694.1_49823001_1 - 7.6e-47 158.7 11.0 1.8e-46 157.5 11.0 1.6 1 1 0 1 1 1 1 Synuclein SOXp PF12336.6 001173447.1_22422001_1 - 3e-38 130.6 4.7 3e-38 130.6 4.7 2.5 4 0 0 4 4 4 1 SOX transcription factor HMG_box PF00505.17 001173447.1_22422001_1 - 1e-27 96.2 3.0 1.7e-27 95.5 3.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001173447.1_22422001_1 - 8.2e-12 45.4 1.6 1.4e-11 44.7 1.6 1.4 1 0 0 1 1 1 1 HMG-box domain HSP70 PF00012.18 001287571.1_09024001_1 - 5.2e-272 903.3 9.4 5.9e-272 903.1 9.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001287571.1_09024001_1 - 4.1e-18 65.1 0.5 9.2e-17 60.7 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.4 001287571.1_09024001_1 - 5.9e-05 23.3 5.2 0.19 12.0 0.1 4.2 4 1 0 4 4 4 2 Cell division protein FtsA DUF4624 PF15417.4 001287571.1_09024001_1 - 0.00063 19.4 0.1 0.23 11.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4624) Hydantoinase_A PF01968.16 001287571.1_09024001_1 - 0.0015 17.7 1.5 0.013 14.7 0.1 2.9 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.8 001287571.1_09024001_1 - 0.0062 15.4 0.8 0.016 14.1 0.5 1.7 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.14 001287571.1_09024001_1 - 0.033 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4795 PF16043.3 001287571.1_09024001_1 - 1.6 8.1 13.0 0.17 11.4 5.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) GPI2 PF06432.9 001167654.1_49822001_1 - 6.4e-88 294.7 8.7 7.2e-88 294.5 8.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DnaJ PF00226.29 001169096.1_40422001_1 - 5.4e-27 93.6 4.8 8e-27 93.0 4.8 1.3 1 0 0 1 1 1 1 DnaJ domain UIM PF02809.18 001169096.1_40422001_1 - 0.00018 21.0 8.5 0.00058 19.5 4.0 2.6 2 0 0 2 2 2 1 Ubiquitin interaction motif RPT PF13446.4 001169096.1_40422001_1 - 0.074 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein Globin PF00042.20 001132429.1_43522001_2 - 1.6e-28 99.3 0.2 2.3e-28 98.8 0.2 1.2 1 0 0 1 1 1 1 Globin Connexin PF00029.17 001172761.1_09923001_1 - 1.7e-83 279.7 7.3 2.4e-83 279.2 7.3 1.2 1 0 0 1 1 1 1 Connexin BPD_transp_2 PF02653.14 001172761.1_09923001_3 - 3.7e-13 49.1 7.6 4.8e-13 48.7 7.6 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Thyroglobulin_1 PF00086.16 001285678.1_09022001_1 - 7.9e-20 70.2 1.1 7.9e-20 70.2 1.1 2.3 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001285678.1_09022001_1 - 7.6e-10 39.2 21.2 7.6e-10 39.2 21.2 2.9 3 0 0 3 3 3 1 Insulin-like growth factor binding protein Integrin_alpha2 PF08441.10 001113771.1_39527001_1 - 4.9e-123 411.3 0.0 6e-123 411.0 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 001113771.1_39527001_1 - 2.1e-27 94.8 29.0 9.9e-08 31.9 3.0 4.9 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.4 001113771.1_39527001_1 - 1.1e-15 57.9 9.5 6.5e-05 23.3 0.1 4.8 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001113771.1_39527001_1 - 7.3e-05 22.3 0.7 0.00017 21.2 0.7 1.7 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.3 001113771.1_39527001_1 - 0.00081 18.9 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family VWA PF00092.26 001082593.1_39527001_1 - 3.3e-40 138.1 0.1 5.1e-40 137.5 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_alpha2 PF08441.10 001082593.1_39527001_1 - 7.9e-40 137.0 0.0 1.2e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 001082593.1_39527001_1 - 5.5e-19 67.8 7.2 3.7e-07 30.0 1.4 3.9 4 0 0 4 4 4 3 FG-GAP repeat VWA_2 PF13519.4 001082593.1_39527001_1 - 3.1e-12 47.0 0.0 7.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.4 001082593.1_39527001_1 - 6.9e-09 36.0 0.1 0.021 15.3 0.0 4.5 4 1 1 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001082593.1_39527001_1 - 1.3e-05 24.7 0.8 1.3e-05 24.7 0.8 1.8 2 0 0 2 2 2 1 Integrin alpha cytoplasmic region DUF11 PF01345.16 001082593.1_39527001_1 - 0.0043 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF11 FG-GAP_2 PF14312.4 001082593.1_39527001_1 - 0.045 13.9 9.3 1.9 8.6 0.1 4.2 5 0 0 5 5 5 0 FG-GAP repeat Connexin PF00029.17 001172748.1_09923001_1 - 1.6e-92 309.2 3.6 2.3e-92 308.7 3.6 1.2 1 0 0 1 1 1 1 Connexin Connexin43 PF03508.11 001172748.1_09923001_1 - 4.8e-11 41.9 15.4 1e-10 40.8 15.4 1.6 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) Connexin40_C PF16791.3 001172748.1_09923001_1 - 8e-06 26.9 2.0 1.3e-05 26.3 2.0 1.3 1 0 0 1 1 1 1 Connexin 40 C-terminal domain Ammonium_transp PF00909.19 001172748.1_09923001_1 - 0.099 11.2 0.2 0.16 10.5 0.2 1.3 1 0 0 1 1 1 0 Ammonium Transporter Family Ninjurin PF04923.10 001172748.1_09923001_1 - 0.13 12.0 0.4 4.2 7.2 0.0 2.6 2 1 0 2 2 2 0 Ninjurin TEX29 PF15839.3 001172748.1_09923001_1 - 6.5 7.3 6.8 1.6 9.3 0.2 2.5 2 1 0 2 2 2 0 Testis-expressed sequence 29 protein Kunitz_BPTI PF00014.21 001135258.1_49823001_3 - 1.9e-55 184.8 46.5 3.2e-19 68.8 10.3 3.3 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain 7tm_1 PF00001.19 001315640.1_49823001_3 - 1.4e-52 178.5 13.9 2.4e-52 177.7 13.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001315640.1_49823001_3 - 1e-08 34.8 10.0 1.6e-08 34.2 10.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.7 001315640.1_49823001_3 - 3.5e-07 29.7 14.7 9.2e-07 28.4 14.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001315640.1_49823001_3 - 0.038 13.6 13.4 0.075 12.6 13.4 1.5 1 1 0 1 1 1 0 Olfactory receptor DUF962 PF06127.9 001315640.1_49823001_3 - 0.21 11.6 3.3 3.4 7.7 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Cementoin PF10511.7 001035224.1_39522001_1 - 7e-41 136.1 125.8 6.9e-07 28.8 6.3 8.8 4 1 6 12 12 12 10 Trappin protein transglutaminase binding domain WAP PF00095.19 001035224.1_39522001_1 - 2.2e-09 37.4 15.6 3.8e-09 36.7 15.6 1.4 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Glutenin_hmw PF03157.11 001035224.1_39522001_1 - 0.00057 18.3 40.4 0.0086 14.4 40.9 1.5 1 1 0 1 1 1 1 High molecular weight glutenin subunit Hexapep PF00132.22 001035224.1_39522001_2 - 0.052 13.2 0.0 7.9 6.2 0.0 3.6 2 1 1 3 3 3 0 Bacterial transferase hexapeptide (six repeats) Bactofilin PF04519.11 001035224.1_39522001_2 - 0.47 10.6 10.0 1.7 8.8 10.0 1.9 1 1 0 1 1 1 0 Polymer-forming cytoskeletal Euplotes_phero PF05842.9 001035224.1_39522001_2 - 9.9 6.6 28.2 6 7.3 9.5 2.9 1 1 1 2 2 2 0 Euplotes octocarinatus mating pheromone protein DnaJ_C PF01556.16 001244163.1_49824001_3 - 4.8e-43 146.7 0.3 6.6e-43 146.2 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 001244163.1_49824001_3 - 6.3e-27 93.3 2.6 1.4e-26 92.3 2.6 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.17 001244163.1_49824001_3 - 1.7e-15 57.0 20.3 3.3e-15 56.1 20.3 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.17 001244163.1_49824001_3 - 0.098 12.5 7.9 1.2 9.0 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.3 001244163.1_49824001_3 - 0.2 11.5 12.1 0.79 9.6 4.6 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Crystall PF00030.17 001173094.1_09922001_3 - 3e-63 209.8 2.8 9.3e-32 108.9 1.5 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.8 001173094.1_09922001_3 - 0.046 13.8 0.3 0.72 9.9 0.0 2.5 2 1 1 3 3 3 0 Beta/Gamma crystallin Integrin_alpha2 PF08441.10 001305890.1_39527001_1 - 4.3e-45 154.3 0.2 7.7e-45 153.5 0.0 1.4 1 1 1 2 2 2 1 Integrin alpha VWA PF00092.26 001305890.1_39527001_1 - 1.6e-41 142.3 0.3 2.5e-41 141.7 0.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.21 001305890.1_39527001_1 - 1.4e-20 73.0 11.1 3e-07 30.3 1.2 3.8 4 0 0 4 4 4 3 FG-GAP repeat VWA_2 PF13519.4 001305890.1_39527001_1 - 1.1e-13 51.6 0.0 3.1e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.4 001305890.1_39527001_1 - 1.5e-06 28.5 0.0 0.0034 17.8 0.0 3.0 2 1 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001305890.1_39527001_1 - 0.00027 20.5 0.7 0.0008 19.1 0.7 1.8 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region VWA_CoxE PF05762.12 001305890.1_39527001_1 - 0.0019 17.5 0.1 0.0054 16.0 0.1 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein FG-GAP_2 PF14312.4 001305890.1_39527001_1 - 0.023 14.8 7.1 2.7 8.2 0.1 4.0 4 0 0 4 4 4 0 FG-GAP repeat Connexin PF00029.17 001172823.1_09922001_2 - 2.4e-85 285.8 8.3 3.3e-85 285.3 8.3 1.2 1 0 0 1 1 1 1 Connexin SPARC_Ca_bdg PF10591.7 001097422.1_49826001_1 - 1.1e-40 138.4 0.1 1.1e-40 138.4 0.1 2.5 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.19 001097422.1_49826001_1 - 1.7e-13 50.2 4.5 1.7e-13 50.2 4.5 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 001097422.1_49826001_1 - 8.2e-12 45.0 2.3 2.7e-11 43.3 2.3 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain FOLN PF09289.8 001097422.1_49826001_1 - 6.2e-11 42.1 6.4 1.5e-10 40.9 6.4 1.7 1 0 0 1 1 1 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.30 001097422.1_49826001_1 - 0.091 12.2 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 EF hand GST_N_3 PF13417.4 001318181.1_29622001_3 - 1e-12 48.1 0.0 2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001318181.1_29622001_3 - 6.2e-12 45.6 0.0 1.5e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001318181.1_29622001_3 - 1.2e-06 28.6 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001318181.1_29622001_3 - 5.1e-05 23.3 0.0 8.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001318181.1_29622001_3 - 0.0018 18.3 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.2 001318181.1_29622001_3 - 0.014 16.0 0.0 0.089 13.4 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.4 001318181.1_29622001_3 - 0.017 14.9 0.1 0.051 13.4 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Lactamase_B_6 PF16661.3 001168964.1_40429001_1 - 0.022 14.1 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain zf-RanBP PF00641.16 001252048.1_49824001_1 - 6.6e-13 47.6 7.4 9.8e-13 47.1 7.4 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.20 001252048.1_49824001_1 - 1.4e-10 40.7 0.0 6.1e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.18 001285732.1_09024001_1 - 3.3e-68 226.1 0.1 1.7e-33 114.5 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.4 001285732.1_09024001_1 - 1.2e-35 123.0 1.7 3.7e-27 95.3 2.1 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.4 001285732.1_09024001_1 - 6e-09 36.2 1.1 0.00092 19.5 0.1 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001285732.1_09024001_1 - 3.9e-08 33.4 0.2 0.0023 18.1 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.4 001285732.1_09024001_1 - 3.5e-06 27.0 0.0 0.021 14.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.11 001285732.1_09024001_1 - 7.2e-06 25.4 0.0 0.053 12.7 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.19 001285732.1_09024001_1 - 6.6e-05 22.7 0.0 0.11 12.2 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Calsequestrin PF01216.15 001285732.1_09024001_1 - 0.00019 20.5 0.1 0.00043 19.3 0.0 1.5 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_4 PF13462.4 001285732.1_09024001_1 - 0.00025 21.1 0.2 0.29 11.1 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_3 PF13192.4 001285732.1_09024001_1 - 0.022 14.7 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain TPR_11 PF13414.4 001315658.1_49823001_1 - 1.2e-17 63.2 5.9 3.6e-08 32.8 0.0 6.8 8 0 0 8 8 7 2 TPR repeat TPR_2 PF07719.15 001315658.1_49823001_1 - 4.9e-17 60.5 25.3 5.4e-05 22.9 0.0 9.7 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_19 PF14559.4 001315658.1_49823001_1 - 6.3e-15 55.3 9.2 0.0012 19.2 0.4 5.5 3 1 3 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.4 001315658.1_49823001_1 - 1.4e-13 50.3 6.3 0.00023 21.6 0.1 7.4 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.26 001315658.1_49823001_1 - 2.2e-10 39.8 27.7 0.00057 19.5 0.1 8.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.4 001315658.1_49823001_1 - 4.5e-10 39.6 18.4 6.5e-05 23.0 0.6 4.9 5 2 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.4 001315658.1_49823001_1 - 7.5e-10 38.4 6.2 0.9 9.9 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.4 001315658.1_49823001_1 - 1.2e-09 37.4 19.5 0.0017 18.3 0.0 8.0 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_16 PF13432.4 001315658.1_49823001_1 - 3.1e-09 37.2 6.9 5.3e-05 23.7 0.2 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.4 001315658.1_49823001_1 - 8.5e-09 34.7 6.6 0.0017 18.1 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.4 001315658.1_49823001_1 - 6.7e-06 26.3 8.9 0.069 13.7 0.1 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.4 001315658.1_49823001_1 - 9e-06 25.0 1.7 0.085 11.9 0.2 4.5 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.12 001315658.1_49823001_1 - 1.2e-05 25.3 5.0 0.3 11.7 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat NARP1 PF12569.6 001315658.1_49823001_1 - 1.7e-05 23.8 5.2 0.00011 21.2 0.0 2.9 2 1 2 4 4 4 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.4 001315658.1_49823001_1 - 1.7e-05 24.4 11.3 0.67 9.8 0.2 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.5 001315658.1_49823001_1 - 5.4e-05 23.2 10.2 3.2 7.9 1.4 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Tcf25 PF04910.12 001315658.1_49823001_1 - 0.0013 17.8 0.0 0.0023 16.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 HTH_WhiA PF02650.12 001315658.1_49823001_1 - 0.033 14.4 1.5 0.22 11.8 1.0 2.5 1 1 1 2 2 2 0 WhiA C-terminal HTH domain SNF5 PF04855.10 001315658.1_49823001_1 - 0.039 13.6 0.2 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 SNF5 / SMARCB1 / INI1 TPR_20 PF14561.4 001315658.1_49823001_1 - 0.04 14.1 7.9 16 5.8 0.5 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat RPM2 PF08579.9 001315658.1_49823001_1 - 0.046 13.9 1.2 5.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) DUF4919 PF16266.3 001315658.1_49823001_1 - 0.066 13.0 2.4 0.4 10.5 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4919) PPR PF01535.18 001315658.1_49823001_1 - 0.082 13.1 2.2 9.3 6.6 0.1 3.9 4 0 0 4 4 4 0 PPR repeat ANAPC5 PF12862.5 001315658.1_49823001_1 - 0.16 11.9 1.4 0.75 9.8 0.0 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 Cementoin PF10511.7 001169021.1_40422001_1 - 1.5e-14 53.0 14.6 3.5e-08 32.9 0.3 3.6 1 1 1 3 3 3 3 Trappin protein transglutaminase binding domain WAP PF00095.19 001169021.1_40422001_1 - 2.2e-09 37.4 12.7 2.2e-09 37.4 12.7 1.6 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Basic PF01586.14 001285602.1_09022001_3 - 6.8e-21 75.1 0.1 2.4e-20 73.4 0.0 1.9 2 1 0 2 2 2 1 Myogenic Basic domain HLH PF00010.24 001285602.1_09022001_3 - 3.9e-13 49.0 6.3 6.2e-13 48.4 6.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myf5 PF12232.6 001285602.1_09022001_3 - 0.0019 18.8 2.0 0.0019 18.8 2.0 1.8 2 0 0 2 2 2 1 Myogenic determination factor 5 DUF758 PF05527.9 001244505.1_49825001_1 - 4.6e-78 261.2 10.2 6.4e-78 260.8 10.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF758) DUF2857 PF11198.6 001244505.1_49825001_1 - 0.18 11.4 1.9 1.1 8.9 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2857) Fibrinogen_C PF00147.16 001109946.1_49824001_1 - 5.2e-74 248.6 12.0 7.1e-74 248.2 12.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Spc29 PF17082.3 001109946.1_49824001_1 - 0.065 12.9 1.2 0.29 10.8 0.0 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 Fer4_NifH PF00142.16 001109946.1_49824001_1 - 0.14 11.4 0.3 0.32 10.3 0.4 1.5 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family zf-C4H2 PF10146.7 001109946.1_49824001_1 - 0.16 12.1 2.3 0.25 11.5 2.3 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Fascin PF06268.11 001168928.1_40423001_1 - 9.9e-63 209.1 0.1 3.2e-28 98.0 0.0 4.4 4 1 0 4 4 4 4 Fascin domain FRG1 PF06229.10 001168928.1_40423001_1 - 2.2e-08 33.9 0.0 0.068 12.7 0.0 4.5 3 2 1 4 4 4 2 FRG1-like domain DUF569 PF04601.11 001168928.1_40423001_1 - 0.00019 21.0 0.0 0.096 12.2 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF569) FGF PF00167.16 001168928.1_40423001_1 - 0.0072 16.3 0.0 0.35 10.8 0.0 3.2 3 1 0 3 3 3 1 Fibroblast growth factor AKAP_110 PF05716.11 001195324.1_49826001_1 - 0 1413.1 0.9 0 1412.9 0.9 1.0 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) RII_binding_1 PF10522.7 001195324.1_49826001_1 - 2.7e-06 26.9 0.0 8.1e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 RII binding domain PARG_cat PF05028.12 001195324.1_49826001_1 - 0.036 13.3 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Poly (ADP-ribose) glycohydrolase (PARG) MFS_1 PF07690.14 001133302.1_43525001_3 - 1.4e-20 73.4 30.5 6.2e-12 45.0 14.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fibrinogen_C PF00147.16 001003926.2_49823001_3 - 6.4e-54 182.9 4.1 8.7e-54 182.5 4.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DASH_Spc34 PF08657.8 001003926.2_49823001_3 - 0.007 16.1 8.1 0.012 15.4 8.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Spc34 DUF1664 PF07889.10 001003926.2_49823001_3 - 0.56 10.1 11.2 0.13 12.1 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.10 001003926.2_49823001_3 - 0.64 10.5 15.7 0.086 13.3 6.0 2.9 1 1 2 3 3 3 0 SlyX NPV_P10 PF05531.10 001003926.2_49823001_3 - 1.6 9.1 13.4 25 5.3 5.8 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.14 001003926.2_49823001_3 - 2.3 6.9 7.1 3.3 6.4 7.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Jnk-SapK_ap_N PF09744.7 001003926.2_49823001_3 - 3 7.9 21.6 0.65 10.1 8.3 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 USP8_interact PF08941.8 001003926.2_49823001_3 - 3 7.5 8.9 1.5 8.4 1.5 2.2 2 0 0 2 2 2 0 USP8 interacting V_ATPase_I PF01496.17 001003926.2_49823001_3 - 3.5 5.3 10.0 5.8 4.5 10.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec34 PF04136.13 001003926.2_49823001_3 - 7.3 6.3 15.7 2.9 7.6 3.2 2.9 1 1 1 3 3 3 0 Sec34-like family DUF342 PF03961.11 001003926.2_49823001_3 - 8.1 4.8 15.2 23 3.3 14.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fascin PF06268.11 001044547.1_49824001_3 - 4.6e-60 200.6 0.0 7.2e-25 87.2 0.1 4.6 4 1 0 4 4 4 4 Fascin domain FRG1 PF06229.10 001044547.1_49824001_3 - 1.3e-10 41.2 0.0 0.092 12.3 0.0 4.8 3 2 2 5 5 5 4 FRG1-like domain DUF569 PF04601.11 001044547.1_49824001_3 - 0.00051 19.6 0.0 0.078 12.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF569) zf-C4 PF00105.16 001037996.1_49823001_1 - 5.7e-28 97.0 12.9 9.6e-28 96.3 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001037996.1_49823001_1 - 2e-20 73.2 0.7 3.5e-20 72.4 0.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DED PF01335.19 001001628.1_49824001_3 - 6.1e-35 119.2 17.4 9.3e-26 89.8 3.2 2.7 3 0 0 3 3 3 2 Death effector domain Peptidase_C14 PF00656.20 001001628.1_49824001_3 - 8.7e-27 94.5 0.0 1.4e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DUF2012 PF09430.8 001001628.1_49824001_3 - 0.12 12.3 0.0 0.43 10.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2012) AF-4 PF05110.11 001168765.1_40427001_1 - 0 1378.6 139.5 0 1378.4 139.5 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein WD40 PF00400.30 001134356.1_49823001_1 - 1.4e-11 44.6 18.7 7e-05 23.4 0.1 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001134356.1_49823001_1 - 2.5e-10 40.4 0.6 0.01 16.0 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001134356.1_49823001_1 - 0.00014 21.7 1.7 0.56 9.9 0.2 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.5 001134356.1_49823001_1 - 0.011 15.3 0.4 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Cortical protein marker for cell polarity SH3_3 PF08239.9 001134356.1_49823001_1 - 0.013 15.6 1.6 0.032 14.4 0.1 2.4 2 1 0 2 2 2 0 Bacterial SH3 domain Spc97_Spc98 PF04130.11 001168727.1_40426001_1 - 1.7e-104 350.5 4.2 1.3e-97 327.7 0.3 2.3 2 0 0 2 2 2 2 Spc97 / Spc98 family AAA_assoc_2 PF16193.3 001168727.1_40426001_1 - 0.11 12.7 0.2 0.46 10.7 0.2 2.1 1 0 0 1 1 1 0 AAA C-terminal domain Fibrinogen_C PF00147.16 001109947.1_49824001_3 - 2.7e-71 239.8 10.8 3.7e-71 239.3 10.8 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain SlyX PF04102.10 001109947.1_49824001_3 - 0.21 12.1 3.7 5.7 7.5 0.8 2.7 2 1 0 2 2 2 0 SlyX RRM_1 PF00076.20 001195331.1_49825001_2 - 7.3e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.5 001195331.1_49825001_2 - 0.02 15.3 49.9 0.053 13.9 49.9 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PCRF PF03462.16 001244934.1_49823001_2 - 4.6e-53 179.8 0.5 4.6e-53 179.8 0.5 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.18 001244934.1_49823001_2 - 7.3e-41 138.6 2.3 1.8e-40 137.4 2.3 1.7 1 0 0 1 1 1 1 RF-1 domain Ribosomal_L26 PF16906.3 001244934.1_49823001_2 - 0.037 14.4 0.4 0.11 12.9 0.4 1.8 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Phage_Mu_Gam PF07352.10 001244934.1_49823001_2 - 1.4 8.7 5.9 0.7 9.6 2.7 1.9 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein ARPC4 PF05856.10 001206535.1_49825001_3 - 1e-82 275.6 8.0 1.3e-82 275.2 8.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.3 001206535.1_49825001_3 - 0.019 15.0 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 Sm_like domain G-patch PF01585.21 001243353.1_49824001_1 - 1.1e-09 37.9 0.4 2.9e-09 36.6 0.4 1.7 1 0 0 1 1 1 1 G-patch domain DUF4632 PF15451.4 001285751.1_09024001_2 - 0.053 13.5 2.0 0.15 12.0 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4632) Hormone_recep PF00104.28 001285751.1_09024001_3 - 1.1e-29 103.4 2.0 1.8e-29 102.7 2.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001285751.1_09024001_3 - 7.8e-27 93.4 14.3 1.3e-26 92.7 14.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RINGv PF12906.5 001130535.1_49829001_2 - 1.7e-14 53.5 8.6 4.9e-14 52.1 8.6 1.9 1 0 0 1 1 1 1 RING-variant domain BSMAP PF12280.6 001243817.1_49824001_3 - 2.5e-66 223.2 2.6 2.6e-66 223.1 0.7 1.8 2 0 0 2 2 2 1 Brain specific membrane anchored protein MHC_I_3 PF16497.3 001163406.1_49823001_1 - 5.5e-19 68.3 0.0 8.7e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 MHC-I family domain MHC_I PF00129.16 001163406.1_49823001_1 - 5.6e-10 38.9 0.0 8.3e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 ABC_membrane PF00664.21 001173091.1_09929001_1 - 1.4e-125 418.4 24.7 3.3e-69 233.5 9.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.25 001173091.1_09929001_1 - 2e-71 238.8 0.3 9.4e-35 120.0 0.0 2.6 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.17 001173091.1_09929001_1 - 1.7e-13 50.4 0.0 1.4e-05 24.5 0.0 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.14 001173091.1_09929001_1 - 5.7e-08 32.7 0.0 0.007 16.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.4 001173091.1_09929001_1 - 8.4e-07 29.4 0.0 0.078 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.4 001173091.1_09929001_1 - 2e-06 27.3 0.3 0.0063 16.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.4 001173091.1_09929001_1 - 2e-06 28.0 0.0 0.13 12.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.10 001173091.1_09929001_1 - 3.2e-05 23.2 0.0 0.025 13.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.4 001173091.1_09929001_1 - 6.3e-05 22.6 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.4 001173091.1_09929001_1 - 8.2e-05 22.3 0.0 0.15 11.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain ABC_ATPase PF09818.7 001173091.1_09929001_1 - 0.00019 20.3 0.4 0.72 8.4 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.4 001173091.1_09929001_1 - 0.00047 19.9 0.0 0.011 15.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.4 001173091.1_09929001_1 - 0.013 15.5 0.0 3.1 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.13 001173091.1_09929001_1 - 0.02 13.7 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.4 001173091.1_09929001_1 - 0.031 13.7 0.4 1.5 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.4 001173091.1_09929001_1 - 0.037 14.4 0.0 0.79 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.18 001173091.1_09929001_1 - 0.045 12.8 0.0 3.1 6.7 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Dala_Dala_lig_N PF01820.19 001173091.1_09929001_1 - 0.047 13.7 0.2 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus SRP54 PF00448.20 001173091.1_09929001_1 - 0.049 13.1 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF3918 PF13056.4 001173091.1_09929001_1 - 0.071 12.6 0.3 12 5.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) AAA_24 PF13479.4 001173091.1_09929001_1 - 0.08 12.5 0.0 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.20 001173091.1_09929001_1 - 0.11 12.8 0.0 20 5.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_5 PF07728.12 001173091.1_09929001_1 - 0.12 12.2 0.0 19 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3852 PF12963.5 001173091.1_09929001_1 - 0.14 12.4 0.8 0.48 10.7 0.3 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF3852) SbcCD_C PF13558.4 001173091.1_09929001_1 - 0.36 11.0 2.5 6.8 6.9 0.1 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Gpi1 PF05024.13 001168823.1_40424001_1 - 1.7e-66 223.8 7.5 3.3e-66 222.9 7.5 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Spc97_Spc98 PF04130.11 001168962.1_40424001_1 - 6.8e-109 365.0 10.6 8.1e-109 364.7 10.6 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family ESSS PF10183.7 001251820.1_09922001_2 - 5e-44 148.7 0.0 6.6e-44 148.3 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peptidase_M10 PF00413.22 001169008.1_40424001_1 - 3.7e-63 212.0 0.3 6.6e-63 211.1 0.3 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.17 001169008.1_40424001_1 - 1.2e-54 181.8 19.5 1.6e-15 56.7 0.6 4.5 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.6 001169008.1_40424001_1 - 1.9e-28 98.0 0.3 3.1e-28 97.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.16 001169008.1_40424001_1 - 3.4e-11 43.0 0.0 7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.22 001169008.1_40424001_1 - 6.6e-05 22.5 1.7 0.14 11.6 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.7 001169008.1_40424001_1 - 0.04 12.7 0.4 0.063 12.1 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.6 001169008.1_40424001_1 - 0.046 12.2 0.1 0.068 11.6 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.4 001169008.1_40424001_1 - 0.057 13.8 0.1 0.17 12.3 0.2 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.9 001169008.1_40424001_1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.3 001169008.1_40424001_1 - 0.099 11.7 0.2 0.18 10.9 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.4 001169008.1_40424001_1 - 0.17 11.4 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Arf PF00025.19 001031791.1_49822001_1 - 2.3e-67 225.7 0.0 2.7e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.20 001031791.1_49822001_1 - 1.6e-17 63.5 0.0 1.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001031791.1_49822001_1 - 2.2e-17 63.2 0.1 3e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.8 001031791.1_49822001_1 - 5.4e-12 45.4 0.9 6e-12 45.2 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001031791.1_49822001_1 - 7.7e-08 32.3 0.1 1.1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.18 001031791.1_49822001_1 - 8.3e-08 31.6 0.4 3.6e-06 26.3 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.25 001031791.1_49822001_1 - 0.00015 21.3 0.1 0.00038 19.9 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.10 001031791.1_49822001_1 - 0.00016 21.0 0.1 0.00024 20.4 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.15 001031791.1_49822001_1 - 0.013 15.2 0.0 0.04 13.5 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein 6PF2K PF01591.16 001031791.1_49822001_1 - 0.023 13.9 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.4 001031791.1_49822001_1 - 0.028 14.5 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.14 001031791.1_49822001_1 - 0.031 14.0 0.2 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NTPase_1 PF03266.13 001031791.1_49822001_1 - 0.15 11.9 1.3 0.41 10.4 0.8 1.8 1 1 1 2 2 2 0 NTPase EF-hand_4 PF12763.5 001169002.1_40424001_1 - 3.2e-18 65.4 0.1 2.3e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.3 001169002.1_40424001_1 - 3.9e-17 61.7 1.1 8.6e-17 60.6 1.1 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.21 001169002.1_40424001_1 - 9.2e-14 51.7 0.0 4.4e-13 49.5 0.0 2.1 2 1 0 2 2 1 1 Dynamin family MMR_HSR1 PF01926.21 001169002.1_40424001_1 - 4.5e-09 36.3 0.0 1.4e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.30 001169002.1_40424001_1 - 0.00034 19.8 0.4 0.0015 17.8 0.1 2.3 2 0 0 2 2 1 1 EF hand GTP_EFTU PF00009.25 001169002.1_40424001_1 - 0.0011 18.4 0.2 0.046 13.1 0.2 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.11 001169002.1_40424001_1 - 0.0019 18.3 0.1 0.39 10.8 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.10 001169002.1_40424001_1 - 0.0035 16.6 0.0 0.035 13.3 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.16 001169002.1_40424001_1 - 0.0083 15.5 0.0 0.83 9.0 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_28 PF13521.4 001169002.1_40424001_1 - 0.01 16.0 0.1 0.056 13.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.4 001169002.1_40424001_1 - 0.039 14.2 0.1 0.29 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.17 001169002.1_40424001_1 - 0.057 12.9 0.0 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.14 001169002.1_40424001_1 - 0.062 12.5 0.1 0.3 10.3 0.0 2.1 3 0 0 3 3 3 0 AIG1 family Ras PF00071.20 001169002.1_40424001_1 - 0.068 12.6 0.1 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Ras family TsaE PF02367.15 001169002.1_40424001_1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_7 PF13499.4 001169002.1_40424001_1 - 0.093 13.1 0.3 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.4 001169002.1_40424001_1 - 0.12 12.3 0.2 0.55 10.2 0.1 2.2 2 0 0 2 2 1 0 EF-hand domain Gp-FAR-1 PF05823.10 001169002.1_40424001_1 - 0.68 10.1 5.7 5.3 7.2 0.0 3.5 3 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Gpi16 PF04113.12 001169029.1_40425001_2 - 5.9e-153 510.1 0.8 1.8e-151 505.3 0.8 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Yip1 PF04893.15 001245980.1_49823001_2 - 5.9e-08 32.5 14.0 8.3e-08 32.0 14.0 1.3 1 0 0 1 1 1 1 Yip1 domain YIF1 PF03878.13 001245980.1_49823001_2 - 0.00016 21.2 9.8 0.01 15.2 9.6 2.1 1 1 0 1 1 1 1 YIF1 Romo1 PF10247.7 001245980.1_49823001_2 - 0.017 15.3 1.3 0.042 14.0 1.3 1.7 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 FAM216B PF15107.4 001244441.1_49823001_3 - 1.8e-45 153.2 4.8 2.6e-45 152.7 4.8 1.2 1 0 0 1 1 1 1 FAM216B protein family DUF1992 PF09350.8 001169041.1_40423001_1 - 5.7e-22 77.5 0.6 1.8e-21 75.9 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1992) DnaJ PF00226.29 001169041.1_40423001_1 - 5.6e-14 51.9 1.5 2.2e-11 43.6 0.1 2.9 2 0 0 2 2 2 2 DnaJ domain NAAA-beta PF15508.4 001169041.1_40423001_1 - 0.083 13.1 0.1 0.63 10.3 0.1 2.4 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Med8 PF10232.7 001169041.1_40423001_1 - 0.1 12.0 5.4 0.043 13.3 1.1 2.2 2 1 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 GAS2 PF02187.15 001244834.1_49826001_2 - 3.2e-32 110.3 0.1 5e-32 109.7 0.1 1.3 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.29 001244834.1_49826001_2 - 5.5e-15 55.4 0.0 7.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain 3HCDH_N PF02737.16 001257492.1_29625001_3 - 1.3e-51 174.9 0.2 1.8e-51 174.4 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.18 001257492.1_29625001_3 - 3.5e-39 134.5 0.2 9.6e-39 133.0 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.20 001257492.1_29625001_3 - 1.5e-37 127.9 0.0 5.9e-27 94.0 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.3 001257492.1_29625001_3 - 1.1e-21 77.6 0.0 2.1e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UDPG_MGDP_dh_N PF03721.12 001257492.1_29625001_3 - 0.0026 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.13 001257492.1_29625001_3 - 0.0044 17.1 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_S49 PF01343.16 001257492.1_29625001_3 - 0.007 16.2 0.1 0.99 9.2 0.0 3.0 3 0 0 3 3 3 1 Peptidase family S49 TrkA_N PF02254.16 001257492.1_29625001_3 - 0.011 15.8 1.2 0.031 14.4 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.17 001257492.1_29625001_3 - 0.041 13.1 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Solute_trans_a PF03619.14 001244266.1_49824001_1 - 4.3e-34 118.1 12.2 5.6e-34 117.8 12.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3267 PF11667.6 001244266.1_49824001_1 - 3 8.0 14.1 6.1 7.0 6.2 2.6 2 0 0 2 2 2 0 Putative zincin peptidase HbrB PF08539.9 001204382.1_49824001_1 - 2.3e-15 56.9 0.3 2.7e-14 53.4 0.1 2.1 1 1 1 2 2 2 2 HbrB-like UPF0688 PF15772.3 001244820.1_49823001_3 - 9.5e-90 300.8 3.0 1.3e-89 300.4 3.0 1.1 1 0 0 1 1 1 1 UPF0688 family ASC PF00858.22 001169099.1_40424001_1 - 8.3e-95 318.0 0.0 9.7e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Trypsin PF00089.24 001304375.1_45723001_3 - 1.8e-56 191.3 0.0 2.3e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001304375.1_45723001_3 - 7.1e-07 29.5 0.2 1.3e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) RINGv PF12906.5 001244831.1_49823001_2 - 5.1e-15 55.2 9.8 1.1e-14 54.1 9.8 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.4 001244831.1_49823001_2 - 0.0027 17.8 9.9 0.0097 16.0 9.9 2.1 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.9 001244831.1_49823001_2 - 0.024 14.4 0.7 0.046 13.5 0.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Vpu PF00558.17 001244831.1_49823001_2 - 0.16 11.7 0.3 0.28 10.9 0.3 1.3 1 0 0 1 1 1 0 Vpu protein zf-C3HC4 PF00097.23 001244831.1_49823001_2 - 3.4 7.5 9.1 1.5 8.7 5.8 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pep_M12B_propep PF01562.17 001246250.1_49827001_1 - 4e-33 114.5 0.0 6.5e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.12 001246250.1_49827001_1 - 1.2e-24 86.4 0.0 1.8e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.17 001246250.1_49827001_1 - 4.6e-24 85.3 0.3 1.9e-23 83.3 0.3 2.0 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.17 001246250.1_49827001_1 - 2.6e-15 56.2 87.5 1.5e-07 31.4 9.7 7.8 8 0 0 8 8 7 5 Thrombospondin type 1 domain Reprolysin_5 PF13688.4 001246250.1_49827001_1 - 1.1e-13 51.7 0.1 2e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.4 001246250.1_49827001_1 - 1.8e-11 44.5 0.0 2.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.4 001246250.1_49827001_1 - 1.9e-10 40.8 0.1 3.4e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.9 001246250.1_49827001_1 - 1.6e-09 38.2 11.0 7e-09 36.1 11.0 2.3 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Reprolysin_4 PF13583.4 001246250.1_49827001_1 - 1.1e-06 28.3 0.3 2.6e-06 27.1 0.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.6 001246250.1_49827001_1 - 0.097 12.1 0.3 0.17 11.4 0.3 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4953 PF16313.3 001246250.1_49827001_1 - 0.098 11.7 0.2 0.15 11.1 0.2 1.1 1 0 0 1 1 1 0 Met-zincin Fe-ADH PF00465.17 001135416.1_43524001_1 - 6.6e-102 340.9 0.0 8.5e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.4 001135416.1_43524001_1 - 3.9e-10 39.7 0.0 1.9e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.4 001135416.1_43524001_1 - 0.02 14.5 0.4 0.031 13.9 0.4 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Beta-lactamase PF00144.22 001243362.1_49824001_1 - 1.8e-51 175.3 0.0 2.5e-29 102.4 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase Ribosomal_L36 PF00444.16 001329980.1_39722001_3 - 2e-14 53.4 8.2 3.8e-14 52.5 8.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 Auxin_repressed PF05564.10 001243404.1_49824001_2 - 2.5 8.7 6.8 1 9.9 2.5 2.5 2 1 0 2 2 2 0 Dormancy/auxin associated protein ATG16 PF08614.9 001190273.1_49824001_1 - 2.2e-45 155.2 28.5 2.2e-45 155.2 28.5 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.30 001190273.1_49824001_1 - 6.2e-34 115.3 14.3 9.8e-07 29.3 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001190273.1_49824001_1 - 5.5e-09 36.1 0.0 0.045 13.9 0.0 4.8 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001190273.1_49824001_1 - 2.3e-05 24.2 0.0 0.61 9.8 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001190273.1_49824001_1 - 0.00029 19.8 0.8 3.3 6.5 0.1 4.0 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2332 PF10094.7 001190273.1_49824001_1 - 0.01 15.2 2.5 0.01 15.2 2.5 2.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2332) Fez1 PF06818.13 001190273.1_49824001_1 - 0.44 10.8 27.4 0.37 11.1 26.0 1.5 1 1 0 1 1 1 0 Fez1 V_ATPase_I PF01496.17 001190273.1_49824001_1 - 1.3 6.7 11.6 1.7 6.3 11.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.10 001190273.1_49824001_1 - 1.3 8.2 26.2 0.94 8.7 24.5 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Phage_GPO PF05929.9 001190273.1_49824001_1 - 2.2 7.7 14.0 1.3 8.4 11.4 1.9 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.12 001190273.1_49824001_1 - 7 6.3 34.0 0.15 11.7 17.7 2.4 1 1 1 2 2 2 0 IncA protein KASH_CCD PF14662.4 001190273.1_49824001_1 - 9 6.0 34.0 0.037 13.7 12.8 2.7 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH AA_permease_2 PF13520.4 001243461.1_49826001_2 - 8.2e-45 153.3 38.5 8.2e-45 153.3 38.5 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.19 001243461.1_49826001_2 - 6e-38 130.5 36.9 6e-38 130.5 36.9 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.4 001243461.1_49826001_2 - 1.2e-20 73.1 10.4 1.2e-20 73.1 10.4 3.9 3 0 0 3 3 3 1 C-terminus of AA_permease Phage_holin_3_6 PF07332.9 001243461.1_49826001_2 - 0.0014 18.5 0.5 0.0014 18.5 0.5 5.3 5 1 1 6 6 6 1 Putative Actinobacterial Holin-X, holin superfamily III LRR_8 PF13855.4 001308829.1_49829001_2 - 4.1e-45 151.2 35.9 7.4e-13 47.9 2.3 6.6 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.5 001308829.1_49829001_2 - 1.1e-11 44.6 48.9 0.0089 16.3 5.7 8.3 5 2 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001308829.1_49829001_2 - 0.00061 19.2 19.2 0.054 12.9 3.2 4.2 2 2 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.31 001308829.1_49829001_2 - 0.12 12.8 30.6 11 6.8 1.0 10.3 10 1 0 10 10 10 0 Leucine Rich Repeat LRRNT PF01462.16 001308829.1_49829001_2 - 0.2 11.2 10.7 0.65 9.6 2.9 2.9 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain UPRTase PF14681.4 001243289.1_49825001_1 - 1.1e-52 178.4 0.0 1.5e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.25 001243289.1_49825001_1 - 0.00059 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Reg_prop PF07494.9 001243289.1_49825001_1 - 0.14 12.4 0.2 0.32 11.2 0.2 1.7 1 0 0 1 1 1 0 Two component regulator propeller Lipocalin PF00061.21 001303466.1_09021001_1 - 1.2e-12 48.1 0.1 1.4e-12 47.9 0.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001303466.1_09021001_1 - 0.00031 20.6 0.0 0.00039 20.2 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family RNase_H2-Ydr279 PF09468.8 001285610.1_09022001_1 - 3.5e-50 171.1 4.6 4.3e-50 170.8 4.6 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) ATG16 PF08614.9 001190272.1_49824001_1 - 2.3e-45 155.1 28.5 2.3e-45 155.1 28.5 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.30 001190272.1_49824001_1 - 7e-34 115.2 14.1 1.1e-06 29.1 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001190272.1_49824001_1 - 6.5e-09 35.8 0.0 0.044 13.9 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001190272.1_49824001_1 - 2.7e-05 24.0 0.0 0.65 9.7 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001190272.1_49824001_1 - 0.00048 19.1 0.8 2.8 6.7 0.1 4.0 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2332 PF10094.7 001190272.1_49824001_1 - 0.004 16.5 1.8 0.004 16.5 1.8 2.3 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2332) ZapB PF06005.10 001190272.1_49824001_1 - 0.007 16.7 4.6 0.007 16.7 4.6 3.7 1 1 2 3 3 3 1 Cell division protein ZapB Fez1 PF06818.13 001190272.1_49824001_1 - 0.44 10.8 27.3 0.31 11.3 25.7 1.5 1 1 0 1 1 1 0 Fez1 APG6 PF04111.10 001190272.1_49824001_1 - 1.6 7.9 26.4 1.4 8.1 25.2 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.17 001190272.1_49824001_1 - 1.9 6.1 12.1 2.5 5.8 12.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.9 001190272.1_49824001_1 - 2 7.8 13.8 1.3 8.5 11.2 1.9 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.12 001190272.1_49824001_1 - 4.9 6.8 33.4 0.16 11.6 17.7 2.4 1 1 1 2 2 2 0 IncA protein LIM PF00412.20 001112685.2_49822001_3 - 1.2e-29 102.1 22.1 1.5e-14 53.9 8.1 2.6 2 0 0 2 2 2 2 LIM domain LBP_BPI_CETP PF01273.23 001281676.1_31323001_3 - 2.5e-30 105.1 8.6 2.5e-30 105.1 8.6 1.4 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain SMK-1 PF04802.13 001244675.1_49826001_1 - 3.6e-81 271.5 5.9 3.6e-81 271.5 5.9 2.0 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.21 001244675.1_49826001_1 - 0.00027 20.7 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.16 001244675.1_49826001_1 - 0.0038 17.4 1.4 0.013 15.6 0.0 2.4 2 0 0 2 2 2 1 RanBP1 domain IGF2_C PF08365.9 001244675.1_49826001_1 - 0.0068 16.3 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Diphtheria_T PF02764.12 001244675.1_49826001_1 - 0.0093 15.9 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 Diphtheria toxin, T domain Nup_retrotrp_bd PF10599.7 001244675.1_49826001_1 - 1.1 9.8 8.5 2.3 8.8 8.5 1.4 1 0 0 1 1 1 0 Retro-transposon transporting motif Alpha-amylase_C PF02806.16 001266287.1_29626001_1 - 5.2e-25 87.6 0.0 1.1e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.16 001266287.1_29626001_1 - 2.2e-17 63.0 0.1 4.5e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.22 001266287.1_29626001_1 - 6.4e-14 52.1 0.3 5.7e-12 45.7 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.4 001266287.1_29626001_1 - 0.0069 15.4 0.1 0.035 13.1 0.1 2.0 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain zf-C2H2 PF00096.24 001293062.1_09021001_1 - 0.099 13.0 2.8 0.18 12.2 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Defensin_beta_2 PF13841.4 001293062.1_09021001_2 - 1.3e-06 28.6 10.2 2.6e-06 27.7 10.2 1.5 1 0 0 1 1 1 1 Beta defensin F420_oxidored PF03807.15 001168989.1_40423001_1 - 2.6e-16 59.9 0.0 5.4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.17 001168989.1_40423001_1 - 1.1e-13 51.3 9.6 3.1e-13 49.8 6.3 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_2 PF03446.13 001168989.1_40423001_1 - 0.0033 17.5 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.17 001168989.1_40423001_1 - 0.0035 16.6 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2768 PF10966.6 001168989.1_40423001_1 - 0.034 14.5 3.0 0.15 12.4 3.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) Shikimate_DH PF01488.18 001168989.1_40423001_1 - 0.039 13.9 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.4 001168989.1_40423001_1 - 0.089 13.1 0.0 0.3 11.4 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding AIF-MLS PF14962.4 001195363.2_49823001_1 - 1.1e-94 315.7 9.7 1.1e-94 315.7 9.7 1.5 2 0 0 2 2 2 1 Mitochondria Localisation Sequence PLA2G12 PF06951.9 001243338.1_49823001_2 - 7.1e-90 299.6 4.4 9.7e-90 299.2 4.4 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Ferlin_C PF16165.3 001318032.1_29729001_3 - 2.1e-68 229.0 0.2 3.8e-68 228.1 0.2 1.5 1 0 0 1 1 1 1 Ferlin C-terminus C2 PF00168.28 001318032.1_29729001_3 - 2.3e-62 207.6 0.0 3e-17 62.7 0.0 8.1 8 0 0 8 8 8 7 C2 domain FerB PF08150.10 001318032.1_29729001_3 - 1.1e-23 83.5 0.0 3.9e-23 81.7 0.0 2.0 2 0 0 2 2 2 1 FerB (NUC096) domain FerI PF08151.10 001318032.1_29729001_3 - 3.8e-16 58.8 0.0 8.7e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain DUF2628 PF10947.6 001318032.1_29729001_3 - 0.034 14.3 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) tRNA_int_endo PF01974.15 001169058.1_40422001_1 - 2.8e-21 75.2 0.0 1.1e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain Presenilin PF01080.15 001169058.1_40422001_1 - 0.15 10.7 1.3 0.16 10.6 1.3 1.1 1 0 0 1 1 1 0 Presenilin RNase_H2-Ydr279 PF09468.8 001169058.1_40422001_1 - 0.4 10.0 2.9 0.53 9.6 2.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) WAP PF00095.19 001305428.1_45722001_1 - 8.2e-21 74.0 66.7 3.6e-08 33.5 14.3 4.2 4 1 0 4 4 4 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' Kunitz_BPTI PF00014.21 001305428.1_45722001_1 - 1.7e-19 69.6 6.8 1.7e-19 69.6 6.8 3.3 3 1 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain dsrm PF00035.24 001206919.1_49829001_1 - 5.4e-20 71.7 0.9 2.4e-12 47.2 0.0 3.2 3 0 0 3 3 3 2 Double-stranded RNA binding motif WW PF00397.24 001206919.1_49829001_1 - 0.0026 17.5 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 WW domain Aminotran_5 PF00266.17 001136510.1_49825001_2 - 2.9e-91 306.1 0.0 3.5e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.19 001136510.1_49825001_2 - 8.5e-10 38.2 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.15 001136510.1_49825001_2 - 0.00021 20.6 0.1 0.00032 20.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.17 001136510.1_49825001_2 - 0.043 12.4 0.0 0.069 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.17 001169013.1_40423001_1 - 3.2e-91 305.9 0.0 3.6e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.19 001169013.1_40423001_1 - 2.6e-10 39.9 0.0 3.8e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.15 001169013.1_40423001_1 - 3.4e-05 23.2 0.1 5.2e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.17 001169013.1_40423001_1 - 0.0053 15.4 0.0 0.01 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MACPF PF01823.17 001097451.2_49826001_1 - 7.7e-37 127.3 0.0 1.3e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain Ldl_recept_a PF00057.16 001097451.2_49826001_1 - 1.8e-08 34.3 12.2 1.8e-08 34.3 12.2 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.17 001097451.2_49826001_1 - 5.8e-06 26.3 30.6 4.2e-05 23.5 8.4 3.1 3 0 0 3 3 3 2 Thrombospondin type 1 domain DUF1869 PF08956.8 001097451.2_49826001_1 - 0.0077 16.0 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1869) Nnf1 PF03980.12 001123163.1_49822001_1 - 1e-22 80.4 0.8 1e-22 80.4 0.8 1.9 1 1 1 2 2 2 1 Nnf1 CASP_C PF08172.10 001123163.1_49822001_1 - 0.0073 15.5 2.1 0.01 15.0 2.1 1.2 1 0 0 1 1 1 1 CASP C terminal Mod_r PF07200.11 001123163.1_49822001_1 - 0.23 11.4 6.3 0.21 11.5 4.4 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LRS4 PF10422.7 001123163.1_49822001_1 - 0.31 10.4 3.4 0.5 9.8 3.4 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 OmpH PF03938.12 001123163.1_49822001_1 - 7 6.5 15.5 3.4 7.5 0.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) C1-set PF07654.13 001130489.1_39525001_1 - 1.3e-06 28.7 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.23 001130489.1_39525001_1 - 0.0025 17.8 0.0 0.09 12.8 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.4 001130489.1_39525001_1 - 0.019 15.5 0.0 0.35 11.4 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Med5 PF08689.8 001130489.1_39525001_1 - 0.11 10.1 0.0 0.15 9.7 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 EGF_2 PF07974.11 001097448.1_49826001_1 - 5.3 7.4 12.3 0.67 10.2 7.3 2.1 2 0 0 2 2 2 0 EGF-like domain MACPF PF01823.17 001097448.1_49826001_3 - 1.4e-32 113.4 0.1 1.4e-32 113.4 0.1 1.6 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.16 001097448.1_49826001_3 - 1e-09 38.3 13.6 1e-09 38.3 13.6 2.2 1 1 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.17 001097448.1_49826001_3 - 0.00021 21.3 4.9 0.00021 21.3 4.9 2.5 2 0 0 2 2 2 1 Thrombospondin type 1 domain Toxin_29 PF08116.9 001097448.1_49826001_3 - 3.3 7.7 8.7 5.5 6.9 4.1 2.9 2 0 0 2 2 2 0 PhTx neurotoxin family CSTF2_hinge PF14327.4 001266798.1_29625001_1 - 4e-29 100.8 3.1 9.8e-29 99.5 3.1 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.20 001266798.1_29625001_1 - 3e-25 87.7 0.0 4.9e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.4 001266798.1_29625001_1 - 1e-18 66.5 15.0 1.6e-18 65.8 12.1 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.3 001266798.1_29625001_1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Sushi PF00084.18 001009724.1_39529001_3 - 7.4e-132 429.9 85.4 2.4e-12 47.1 1.2 15.4 15 0 0 15 15 15 15 Sushi repeat (SCR repeat) Ras PF00071.20 001266456.2_29623001_2 - 1.4e-55 187.2 0.4 1.8e-55 186.8 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001266456.2_29623001_2 - 6e-19 68.3 0.0 1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001266456.2_29623001_2 - 4e-10 39.3 0.0 5.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001266456.2_29623001_2 - 1.6e-08 34.5 0.1 7.3e-05 22.6 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001266456.2_29623001_2 - 0.00018 21.0 0.2 0.00048 19.6 0.1 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001266456.2_29623001_2 - 0.006 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.4 001266456.2_29623001_2 - 0.026 14.0 0.1 0.11 12.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain ThiF PF00899.19 001266456.2_29623001_2 - 0.12 11.5 1.4 0.18 11.0 0.1 1.8 2 0 0 2 2 2 0 ThiF family Aminotran_5 PF00266.17 001171334.1_37923001_1 - 7.8e-92 307.9 0.0 9.7e-92 307.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.19 001171334.1_37923001_1 - 5.1e-10 39.0 0.1 7.7e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.15 001171334.1_37923001_1 - 2.7e-05 23.5 0.0 4.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.17 001171334.1_37923001_1 - 0.0074 14.9 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SSXT PF05030.10 001145186.2_39522001_1 - 2.7e-31 106.9 1.4 3.5e-31 106.5 1.4 1.1 1 0 0 1 1 1 1 SSXT protein (N-terminal region) AAA PF00004.27 001243418.1_49825001_1 - 1.3e-40 138.8 0.0 2.4e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.8 001243418.1_49825001_1 - 2.1e-27 94.7 0.2 5.1e-27 93.5 0.2 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.16 001243418.1_49825001_1 - 1.3e-24 85.9 8.9 2.7e-24 84.9 8.9 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain IstB_IS21 PF01695.15 001243418.1_49825001_1 - 1.9e-05 24.3 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.11 001243418.1_49825001_1 - 2.3e-05 23.4 0.0 3.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.4 001243418.1_49825001_1 - 4.4e-05 23.6 0.1 0.0047 17.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.4 001243418.1_49825001_1 - 5.5e-05 23.5 0.1 0.0062 16.8 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.4 001243418.1_49825001_1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.10 001243418.1_49825001_1 - 0.00017 20.8 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.12 001243418.1_49825001_1 - 0.00026 20.9 0.0 0.00064 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.11 001243418.1_49825001_1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.4 001243418.1_49825001_1 - 0.0013 18.2 0.1 2 7.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.4 001243418.1_49825001_1 - 0.0014 19.0 0.0 0.0037 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.12 001243418.1_49825001_1 - 0.003 17.6 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.4 001243418.1_49825001_1 - 0.0044 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.20 001243418.1_49825001_1 - 0.025 14.9 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.4 001243418.1_49825001_1 - 0.042 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.14 001243418.1_49825001_1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.4 001243418.1_49825001_1 - 0.061 13.6 0.1 0.35 11.2 0.0 2.3 3 0 0 3 3 2 0 AAA domain ATPase PF06745.11 001243418.1_49825001_1 - 0.065 12.4 0.1 6.3 5.9 0.0 2.3 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.19 001243418.1_49825001_1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.10 001243418.1_49825001_1 - 0.11 12.3 0.0 0.47 10.2 0.0 2.1 1 1 0 1 1 1 0 NACHT domain YhdB PF14148.4 001243418.1_49825001_1 - 0.18 11.8 1.3 0.32 11.0 1.3 1.4 1 0 0 1 1 1 0 YhdB-like protein Sigma54_activat PF00158.24 001243418.1_49825001_1 - 0.19 11.3 0.0 0.46 10.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain TPR_2 PF07719.15 001243418.1_49825001_1 - 1.4 9.1 5.2 0.51 10.4 1.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Uteroglobin PF01099.15 001178105.1_39521001_1 - 1.1e-20 73.5 0.0 1.3e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Uteroglobin family Feld-I_B PF09252.8 001178105.1_39521001_1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain Spc7_N PF15402.4 001178105.1_39521001_1 - 0.019 13.1 0.1 0.022 12.9 0.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PUL PF08324.9 001178105.1_39521001_1 - 0.05 12.8 0.0 0.1 11.8 0.0 1.5 1 1 0 1 1 1 0 PUL domain Mito_carr PF00153.25 001190189.1_49824001_1 - 3e-61 203.2 0.1 2.1e-20 72.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-A20 PF01754.14 001163605.1_39522001_1 - 8.3e-13 47.9 8.8 2.5e-12 46.3 8.8 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.14 001163605.1_39522001_1 - 1.1e-09 38.1 8.2 1.1e-09 38.1 8.2 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger FAM53 PF15242.4 001163605.1_39522001_1 - 0.23 11.1 12.4 0.31 10.7 12.4 1.1 1 0 0 1 1 1 0 Family of FAM53 CK_II_beta PF01214.16 001142511.2_39522001_2 - 2.9e-86 287.9 0.0 3.4e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CCDC24 PF15669.3 001142511.2_39522001_2 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Guanylate_kin PF00625.19 001132093.1_43527001_3 - 9.8e-50 168.6 0.1 1.8e-49 167.8 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.6 001132093.1_43527001_3 - 2.1e-22 78.8 6.5 2.1e-22 78.8 6.5 2.2 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.26 001132093.1_43527001_3 - 0.0033 16.9 0.1 0.0079 15.6 0.1 1.7 2 0 0 2 2 2 1 SH3 domain IL8 PF00048.18 001114289.2_49821001_1 - 1.2e-17 63.7 0.5 1.2e-17 63.7 0.5 2.0 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like Rtf2 PF04641.10 001114289.2_49821001_1 - 0.36 10.0 10.7 1.9 7.6 9.6 1.8 1 1 1 2 2 2 0 Rtf2 RING-finger 7tm_1 PF00001.19 001314255.1_09023001_1 - 3.1e-26 92.1 6.9 3.7e-26 91.8 6.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.7 001314255.1_09023001_1 - 6e-06 25.6 6.9 1.2e-05 24.7 6.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srb PF02175.14 001314255.1_09023001_1 - 0.00059 19.6 1.1 0.0009 19.0 0.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Srsx PF10320.7 001314255.1_09023001_1 - 0.015 14.5 7.7 0.036 13.3 7.7 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Metallothio PF00131.18 001301277.1_39721001_1 - 5.8e-19 67.9 65.3 9.6e-19 67.1 65.3 1.4 1 0 0 1 1 1 1 Metallothionein MSA-2c PF12238.6 001301277.1_39721001_2 - 0.8 9.5 4.0 0.94 9.3 4.0 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Retinal PF15449.4 001301277.1_39721001_2 - 2 6.0 6.0 2.2 5.8 6.0 1.0 1 0 0 1 1 1 0 Retinal protein HlyIII PF03006.18 001243668.1_49824001_1 - 3e-49 167.6 11.5 4.2e-49 167.1 11.5 1.2 1 0 0 1 1 1 1 Haemolysin-III related MARVEL PF01284.21 001171388.1_37922001_1 - 1.1e-33 116.2 27.7 1.4e-18 67.2 4.4 2.1 2 0 0 2 2 2 2 Membrane-associating domain ABC2_membrane_5 PF13346.4 001171388.1_37922001_1 - 6.1 6.2 12.5 0.37 10.2 3.8 2.4 1 1 0 2 2 2 0 ABC-2 family transporter protein HlyIII PF03006.18 001171388.1_37922001_1 - 9.6 5.7 19.0 42 3.6 2.1 2.8 1 1 1 2 2 2 0 Haemolysin-III related CD225 PF04505.10 001123170.1_49824001_1 - 4.6e-21 74.6 1.4 8.6e-21 73.7 1.4 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Zip PF02535.20 001134079.1_43529001_2 - 1.2e-104 350.0 23.8 4.3e-102 341.6 23.8 2.4 1 1 0 1 1 1 1 ZIP Zinc transporter UQ_con PF00179.24 001257356.1_49823001_1 - 1.5e-52 176.8 0.1 2e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.20 001257356.1_49823001_1 - 0.0086 16.2 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 RWD domain EF-hand_7 PF13499.4 001112821.1_39522001_3 - 6.1e-31 106.6 8.6 1.1e-17 64.1 3.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001112821.1_39522001_3 - 3.1e-30 101.3 20.2 2.7e-08 32.6 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001112821.1_39522001_3 - 6e-25 86.6 16.8 1.9e-13 49.8 0.5 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.4 001112821.1_39522001_3 - 2.4e-24 83.0 12.7 5.6e-07 28.9 0.1 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001112821.1_39522001_3 - 1.1e-20 72.0 19.8 1.3e-05 24.4 0.1 4.7 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.4 001112821.1_39522001_3 - 1.2e-16 60.6 0.6 1.4e-07 31.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001112821.1_39522001_3 - 6.2e-08 32.4 5.9 0.0009 19.0 0.3 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001112821.1_39522001_3 - 2e-06 27.9 0.4 0.00068 19.8 0.3 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001112821.1_39522001_3 - 0.0007 20.3 0.0 0.8 10.5 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain DUF1456 PF07308.11 001112821.1_39522001_3 - 0.00075 19.7 0.8 0.079 13.2 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1456) TerB PF05099.11 001112821.1_39522001_3 - 0.00098 19.0 1.8 0.23 11.3 0.8 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB p25-alpha PF05517.10 001112821.1_39522001_3 - 0.019 15.0 0.3 0.17 11.9 0.1 2.1 1 1 0 2 2 2 0 p25-alpha Caleosin PF05042.11 001112821.1_39522001_3 - 0.02 14.7 1.7 10 5.9 0.2 3.7 1 1 2 3 3 3 0 Caleosin related protein DUF533 PF04391.10 001112821.1_39522001_3 - 0.043 13.3 2.4 0.056 12.9 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF533) SurA_N_2 PF13623.4 001112821.1_39522001_3 - 0.047 13.4 0.2 0.11 12.2 0.2 1.6 1 1 1 2 2 2 0 SurA N-terminal domain DUF1707 PF08044.9 001112821.1_39522001_3 - 0.13 12.2 2.8 17 5.4 0.3 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) FlgD PF03963.12 001112821.1_39522001_3 - 0.14 12.4 0.1 3.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Cation_efflux PF01545.19 001139470.1_49824001_2 - 9.5e-46 155.9 1.7 1.3e-40 139.2 0.1 2.1 2 0 0 2 2 2 2 Cation efflux family ZT_dimer PF16916.3 001139470.1_49824001_2 - 0.078 13.0 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Serpin PF00079.18 001139447.1_39523001_1 - 7.2e-82 275.5 0.0 8.3e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) V-ATPase_H_N PF03224.12 001132619.1_43525001_2 - 1.3e-102 343.1 10.6 1.6e-102 342.9 8.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.6 001132619.1_43525001_2 - 2.6e-46 156.4 2.2 2.9e-46 156.2 0.3 2.1 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.21 001132619.1_43525001_2 - 4.6e-06 26.3 0.3 0.029 14.3 0.0 4.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.11 001132619.1_43525001_2 - 0.00089 18.7 0.1 0.0026 17.1 0.0 1.7 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.4 001132619.1_43525001_2 - 0.0016 18.6 0.1 1.6 9.0 0.0 3.4 3 1 0 3 3 3 1 HEAT repeats DUF2326 PF10088.7 001132619.1_43525001_2 - 0.0059 16.2 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2326) HEAT PF02985.20 001132619.1_43525001_2 - 0.054 13.6 0.1 1.1 9.5 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat UCH PF00443.27 001132619.1_43525001_2 - 0.38 10.1 1.7 0.63 9.4 1.7 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Trypsin PF00089.24 001305930.1_29723001_3 - 6.3e-66 222.2 0.1 7.3e-66 222.0 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001305930.1_29723001_3 - 1.1e-06 29.4 0.0 1.6e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001305930.1_29723001_3 - 2.4e-06 27.8 0.0 4.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) adh_short PF00106.23 001244532.1_49824001_3 - 3e-45 154.0 0.0 3.8e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001244532.1_49824001_3 - 6.3e-38 130.5 0.2 8.5e-38 130.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001244532.1_49824001_3 - 7.7e-10 38.8 0.1 1.1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001244532.1_49824001_3 - 2e-05 24.0 0.2 0.00017 21.0 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.4 001244532.1_49824001_3 - 0.00015 21.6 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.3 001244532.1_49824001_3 - 0.0023 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.11 001244532.1_49824001_3 - 0.0033 16.9 0.1 0.023 14.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.15 001244532.1_49824001_3 - 0.0039 17.6 0.2 0.15 12.5 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.16 001244532.1_49824001_3 - 0.0047 17.1 0.3 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.15 001244532.1_49824001_3 - 0.022 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Guanylin PF02058.13 001244532.1_49824001_3 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Guanylin precursor OpcA PF07239.9 001243619.1_49824001_1 - 0.023 13.7 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein OpcA zf-H2C2_2 PF13465.4 001132858.1_43527001_2 - 7.6e-17 60.8 36.1 1.7e-07 31.3 2.8 6.6 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.24 001132858.1_43527001_2 - 7.3e-14 51.2 43.1 0.00015 21.9 1.3 7.1 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001132858.1_43527001_2 - 1.2e-06 28.7 50.8 0.0019 18.7 1.1 7.6 7 0 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_5 PF13909.4 001132858.1_43527001_2 - 0.00023 20.7 5.5 0.00063 19.3 0.9 5.1 4 0 0 4 4 4 2 C2H2-type zinc-finger domain GAGA PF09237.9 001132858.1_43527001_2 - 0.05 13.3 2.7 0.3 10.8 0.1 2.6 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.5 001132858.1_43527001_2 - 0.13 12.6 0.1 0.13 12.6 0.1 5.9 4 1 1 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 001132858.1_43527001_2 - 0.51 10.0 12.5 0.22 11.2 0.3 4.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-CHCC PF10276.7 001132858.1_43527001_2 - 4.7 7.2 8.3 0.67 9.9 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger domain 7tm_1 PF00001.19 001173416.1_09923001_1 - 5e-52 176.7 16.7 1.2e-51 175.4 16.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.20 001195521.1_29624001_2 - 4.5e-21 74.3 0.2 7.8e-21 73.6 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001195521.1_29624001_2 - 1.9e-08 33.8 0.0 3.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.21 001195521.1_29624001_2 - 0.00012 21.9 2.2 0.00012 21.9 2.2 1.8 2 0 0 2 2 2 1 Zinc knuckle RRM_7 PF16367.3 001195521.1_29624001_2 - 0.024 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif zf-CCHC_3 PF13917.4 001195521.1_29624001_2 - 0.048 13.5 1.2 0.09 12.6 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF1201 PF06716.9 001195521.1_29624001_3 - 0.3 11.0 5.3 0.7 9.8 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) OB_NTP_bind PF07717.14 001105166.1_29627001_1 - 3e-22 78.7 0.0 1e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.21 001105166.1_29627001_1 - 1.9e-20 73.0 0.0 1.9e-20 73.0 0.0 3.4 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.29 001105166.1_29627001_1 - 4.3e-12 46.3 0.0 1.1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.27 001105166.1_29627001_1 - 3e-07 30.2 0.0 1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.4 001105166.1_29627001_1 - 2.4e-05 24.0 0.6 6.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.4 001105166.1_29627001_1 - 0.0012 19.0 0.0 0.0049 17.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.4 001105166.1_29627001_1 - 0.0084 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.18 001105166.1_29627001_1 - 0.01 14.8 0.0 0.039 12.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein SecA_DEAD PF07517.12 001105166.1_29627001_1 - 0.018 14.2 0.3 0.054 12.6 0.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain Flavi_DEAD PF07652.12 001105166.1_29627001_1 - 0.03 14.1 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.20 001105166.1_29627001_1 - 0.052 13.0 0.1 0.17 11.3 0.1 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.4 001105166.1_29627001_1 - 1.6 9.1 0.0 1.6 9.1 0.0 3.1 2 1 1 3 3 1 0 AAA domain IL8 PF00048.18 001305907.1_29721001_1 - 5.6e-23 80.7 2.9 6.9e-23 80.4 2.9 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF4725 PF15854.3 001305907.1_29721001_1 - 0.0078 16.3 0.2 0.0096 16.0 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4725) Mito_carr PF00153.25 001256816.1_39523001_2 - 1.3e-66 220.4 0.9 1.4e-21 76.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein G-gamma PF00631.20 001193395.1_29621001_1 - 8.4e-19 67.2 0.0 8.9e-19 67.1 0.0 1.0 1 0 0 1 1 1 1 GGL domain Zip PF02535.20 001266399.1_29625001_1 - 1.8e-51 175.2 7.2 4.8e-49 167.2 7.2 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Integrin_beta PF00362.16 001097424.1_49825001_1 - 2.4e-103 345.0 0.0 4.2e-103 344.2 0.0 1.4 1 0 0 1 1 1 1 Integrin beta chain VWA domain PSI_integrin PF17205.1 001097424.1_49825001_1 - 2.1e-12 46.6 7.2 2.1e-12 46.6 7.2 4.4 4 0 0 4 4 4 1 Integrin plexin domain EGF_2 PF07974.11 001097424.1_49825001_1 - 1.8e-07 31.2 54.7 4.2e-05 23.7 13.3 6.2 6 0 0 6 6 6 3 EGF-like domain Sigma_reg_N PF13800.4 001097424.1_49825001_1 - 0.048 13.8 0.3 0.12 12.6 0.3 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal CHCH PF06747.11 001190197.1_49822001_3 - 1.5e-09 37.6 2.1 1.5e-09 37.6 2.1 2.4 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.8 001190197.1_49822001_3 - 0.0015 18.3 0.8 0.0015 18.3 0.8 2.4 1 1 2 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.3 001190197.1_49822001_3 - 0.024 14.5 10.9 0.041 13.8 2.6 3.2 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cdd1 PF11731.6 001190197.1_49822001_3 - 0.16 12.1 2.0 10 6.3 0.2 2.3 1 1 1 2 2 2 0 Pathogenicity locus UCR_hinge PF02320.14 001190197.1_49822001_3 - 6.7 6.9 9.5 19 5.4 3.9 2.9 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Abhydrolase_1 PF00561.18 001126346.1_39523001_1 - 1.6e-32 113.0 0.6 2e-32 112.7 0.6 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.14 001126346.1_39523001_1 - 9e-25 85.9 0.0 1.7e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.6 001126346.1_39523001_1 - 1.9e-05 23.9 0.0 0.00042 19.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF779 PF05610.9 001126346.1_39523001_1 - 0.052 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF779) HTH_AraC PF00165.21 001126346.1_39523001_1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family NUDIX PF00293.26 001132043.1_43523001_3 - 6.1e-18 65.0 0.0 9.8e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.4 001132043.1_43523001_3 - 0.044 13.6 0.0 0.15 11.9 0.0 2.0 1 1 0 1 1 1 0 NUDIX domain zf-C2H2 PF00096.24 001164219.1_39523001_1 - 2.4e-16 59.1 21.8 1.1e-05 25.4 2.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001164219.1_39523001_1 - 9.1e-11 41.6 11.2 3.9e-07 30.1 3.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001164219.1_39523001_1 - 4.6e-08 33.1 19.8 0.013 16.1 2.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.3 001164219.1_39523001_1 - 0.43 11.1 6.0 9.9 6.7 1.8 2.6 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2HE PF16278.3 001164219.1_39523001_1 - 0.78 10.1 5.3 10 6.6 1.4 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.5 001164219.1_39523001_1 - 0.99 9.7 7.9 3.2 8.1 1.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.4 001164219.1_39523001_1 - 3.1 7.7 11.2 0.26 11.1 1.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.3 001164219.1_39523001_1 - 3.2 7.4 8.8 13 5.5 0.8 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Actin PF00022.17 001314342.1_09023001_3 - 2.7e-150 500.4 0.0 8.6e-150 498.7 0.0 1.6 1 1 0 1 1 1 1 Actin LRR_6 PF13516.4 001319358.1_29524001_2 - 1.1e-10 40.6 10.8 0.31 11.1 0.0 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.5 001319358.1_29524001_2 - 3.2e-06 27.2 2.4 0.028 14.7 0.7 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001319358.1_29524001_2 - 1.8 9.2 7.5 2e+02 3.0 0.1 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat Omega-toxin PF06357.9 001319358.1_29524001_3 - 0.67 9.7 3.6 1.8 8.3 3.6 1.6 1 0 0 1 1 1 0 Omega-atracotoxin Pkinase PF00069.23 001166314.1_49823001_1 - 5.2e-75 252.1 0.0 6.1e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001166314.1_49823001_1 - 2.1e-32 112.3 0.0 2.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001166314.1_49823001_1 - 1.5e-06 27.6 0.1 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.9 001166314.1_49823001_1 - 0.00012 21.2 0.1 0.0017 17.3 0.0 2.1 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.21 001166314.1_49823001_1 - 0.0079 16.0 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.20 001166314.1_49823001_1 - 0.047 13.2 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.4 001166314.1_49823001_1 - 0.054 13.0 0.1 0.5 9.8 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LRR_8 PF13855.4 001030534.1_49826001_2 - 1e-25 89.1 37.8 1.5e-13 50.2 1.2 6.6 3 2 3 7 7 7 6 Leucine rich repeat TIR PF01582.18 001030534.1_49826001_2 - 3.9e-19 69.0 0.0 7.2e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001030534.1_49826001_2 - 1e-15 57.3 41.4 2.7e-05 24.3 4.0 8.2 4 3 6 10 10 10 8 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001030534.1_49826001_2 - 5.6e-09 36.1 0.0 1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001030534.1_49826001_2 - 0.0006 19.5 35.4 2.1 8.5 0.2 10.7 13 0 0 13 13 13 3 Leucine Rich repeat LRR_9 PF14580.4 001030534.1_49826001_2 - 0.0083 15.5 14.9 0.68 9.3 0.4 3.7 2 1 2 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.31 001030534.1_49826001_2 - 0.011 15.9 37.1 11 6.8 0.1 11.4 8 3 1 9 9 9 0 Leucine Rich Repeat LRRCT PF01463.22 001030534.1_49826001_2 - 0.013 15.8 0.0 0.054 13.9 0.0 2.1 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Pentapeptide_4 PF13599.4 001030534.1_49826001_2 - 0.051 13.6 4.9 0.72 9.9 0.2 4.2 3 2 2 5 5 5 0 Pentapeptide repeats (9 copies) DUF1863 PF08937.9 001030534.1_49826001_2 - 0.085 13.0 0.0 0.46 10.7 0.0 2.0 1 1 1 2 2 2 0 MTH538 TIR-like domain (DUF1863) Flavodoxin_2 PF02525.15 001159613.1_49824001_3 - 4.5e-50 170.0 0.0 6e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.13 001159613.1_49824001_3 - 4.3e-10 39.4 0.0 7.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase RRM_1 PF00076.20 001195549.2_29629001_3 - 1.5e-31 107.9 0.0 4.6e-16 58.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001195549.2_29629001_3 - 0.003 17.4 0.0 0.02 14.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.3 001195549.2_29629001_3 - 0.0076 16.0 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Corona_nucleoca PF00937.16 001195549.2_29629001_3 - 0.061 12.2 6.5 0.088 11.7 6.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RRM_7 PF16367.3 001195549.2_29629001_3 - 0.091 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RRM_3 PF08777.9 001195549.2_29629001_3 - 0.11 12.5 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif PRP38_assoc PF12871.5 001195549.2_29629001_3 - 7.8 7.0 26.8 14 6.2 26.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Mito_carr PF00153.25 001127274.1_39522001_1 - 1.1e-55 185.3 1.5 7.2e-22 77.0 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein zf-H2C2_2 PF13465.4 001110174.1_49824001_1 - 2.7e-49 163.4 94.4 8.7e-10 38.5 0.7 11.5 11 0 0 11 11 11 8 Zinc-finger double domain zf-C2H2 PF00096.24 001110174.1_49824001_1 - 3.3e-38 127.9 97.9 3.6e-05 23.8 0.4 11.5 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001110174.1_49824001_1 - 2.2e-29 99.4 94.7 0.00092 19.7 1.5 11.4 11 0 0 11 11 11 11 C2H2-type zinc finger zf-H2C2_5 PF13909.4 001110174.1_49824001_1 - 9.8e-18 63.5 81.7 6.8e-06 25.6 2.4 10.7 11 0 0 11 11 11 6 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.8 001110174.1_49824001_1 - 0.0059 16.6 1.0 0.0059 16.6 1.0 7.1 5 2 1 7 7 7 2 Zinc ribbon domain GAGA PF09237.9 001110174.1_49824001_1 - 0.011 15.4 28.9 2.3 8.0 0.1 7.3 4 2 4 8 8 8 0 GAGA factor zf-C2H2_jaz PF12171.6 001110174.1_49824001_1 - 0.012 15.8 60.4 0.36 11.1 0.2 11.1 10 1 1 11 11 11 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.11 001110174.1_49824001_1 - 0.059 13.3 53.9 0.31 11.0 1.0 7.0 1 1 6 7 7 7 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.4 001110174.1_49824001_1 - 0.21 10.9 7.2 4.6 6.7 0.1 4.0 3 0 0 3 3 3 0 zinc-ribbon domain tRNA-synt_2d PF01409.18 001110174.1_49824001_1 - 0.82 9.0 4.2 0.16 11.3 0.5 1.7 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Mito_carr PF00153.25 001127276.1_39522001_1 - 1.9e-58 194.2 2.6 4.7e-20 71.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.23 001142509.1_39524001_2 - 1.2e-78 264.0 0.0 1.4e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001142509.1_39524001_2 - 3e-35 121.6 0.0 4.4e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001142509.1_39524001_2 - 0.0051 16.0 0.0 0.13 11.4 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.21 001142509.1_39524001_2 - 0.023 14.5 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SOXp PF12336.6 001285672.1_09022001_1 - 8.5e-38 129.2 4.1 8.5e-38 129.2 4.1 2.5 4 0 0 4 4 4 1 SOX transcription factor HMG_box PF00505.17 001285672.1_09022001_1 - 1e-27 96.2 3.0 1.7e-27 95.5 3.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001285672.1_09022001_1 - 8.1e-12 45.4 1.6 1.4e-11 44.7 1.6 1.4 1 0 0 1 1 1 1 HMG-box domain AA_permease_2 PF13520.4 001130973.1_49825001_2 - 5.7e-48 163.7 15.3 5.7e-48 163.7 15.3 2.6 2 1 1 3 3 3 1 Amino acid permease AA_permease PF00324.19 001130973.1_49825001_2 - 5.3e-30 104.3 20.4 5.3e-30 104.3 20.4 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.4 001130973.1_49825001_2 - 5.8e-24 83.8 5.4 5.8e-24 83.8 5.4 3.4 5 0 0 5 5 5 1 C-terminus of AA_permease TPR_8 PF13181.4 001134081.1_43527001_3 - 4.3e-20 70.0 13.3 0.0056 16.7 0.0 9.8 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_2 PF07719.15 001134081.1_43527001_3 - 7.3e-20 69.3 9.6 0.00019 21.2 0.0 10.9 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_1 PF00515.26 001134081.1_43527001_3 - 4.6e-17 60.9 13.1 0.00064 19.3 0.0 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.4 001134081.1_43527001_3 - 5.9e-11 41.5 4.4 1.4 9.0 0.0 9.4 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.4 001134081.1_43527001_3 - 2.2e-10 40.8 16.0 0.082 13.3 0.1 7.3 4 3 3 8 8 7 5 Tetratricopeptide repeat ANAPC3 PF12895.5 001134081.1_43527001_3 - 2.5e-09 37.1 10.8 0.036 14.1 0.4 5.7 4 3 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.4 001134081.1_43527001_3 - 3.2e-09 36.7 7.7 24 5.9 0.0 10.2 6 3 4 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.4 001134081.1_43527001_3 - 4.1e-08 33.6 3.5 12 6.6 0.2 8.3 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_11 PF13414.4 001134081.1_43527001_3 - 6.3e-07 28.8 4.8 0.0043 16.6 0.0 6.6 7 1 0 7 7 7 1 TPR repeat TPR_12 PF13424.4 001134081.1_43527001_3 - 1.8e-06 28.0 22.7 0.015 15.4 0.4 8.0 7 4 2 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.4 001134081.1_43527001_3 - 2.9e-06 27.4 6.5 39 5.0 0.0 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_15 PF13429.4 001134081.1_43527001_3 - 4.3e-06 26.0 0.8 0.84 8.7 0.0 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.4 001134081.1_43527001_3 - 8.5e-06 25.7 11.1 0.4 10.8 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.4 001134081.1_43527001_3 - 4.8e-05 23.5 5.1 1.7 8.9 0.0 6.6 6 2 3 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.4 001134081.1_43527001_3 - 5.1e-05 23.3 15.3 0.35 11.2 0.0 8.5 10 0 0 10 10 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.7 001134081.1_43527001_3 - 0.0064 15.8 0.0 0.036 13.4 0.0 2.3 2 0 0 2 2 2 1 SHNi-TPR TPR_4 PF07721.12 001134081.1_43527001_3 - 0.011 16.1 0.8 1.7 9.4 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_10 PF13374.4 001134081.1_43527001_3 - 0.04 13.7 12.0 6 6.8 0.1 7.4 9 1 1 10 10 9 0 Tetratricopeptide repeat Sel1 PF08238.10 001134081.1_43527001_3 - 0.17 12.5 0.8 28 5.4 0.0 3.8 3 0 0 3 3 3 0 Sel1 repeat TPR_21 PF09976.7 001134081.1_43527001_3 - 0.19 11.3 2.1 2.2 7.9 0.0 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain Foie-gras_1 PF11817.6 001134081.1_43527001_3 - 0.21 11.0 4.1 24 4.3 0.0 3.9 3 1 1 4 4 4 0 Foie gras liver health family 1 RNA_pol_3_Rpc31 PF11705.6 001134081.1_43527001_3 - 1.2 9.2 15.6 2.3 8.3 15.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.8 001134081.1_43527001_3 - 4.7 6.3 16.9 7.3 5.7 16.9 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.13 001134081.1_43527001_3 - 9.9 4.7 11.2 15 4.1 11.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SPARC_Ca_bdg PF10591.7 001166202.1_39522001_1 - 2.2e-40 137.4 0.2 5.4e-40 136.1 0.2 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.19 001166202.1_39522001_1 - 1.2e-13 50.7 4.4 1.2e-13 50.7 4.4 2.6 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 001166202.1_39522001_1 - 1.4e-11 44.2 2.2 5.1e-11 42.4 2.2 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain FOLN PF09289.8 001166202.1_39522001_1 - 2.3e-10 40.3 6.4 2.3e-10 40.3 6.4 2.1 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.30 001166202.1_39522001_1 - 0.047 13.1 0.1 0.42 10.1 0.1 2.4 2 0 0 2 2 2 0 EF hand hEGF PF12661.5 001166202.1_39522001_1 - 0.056 14.0 1.4 0.24 12.0 1.4 2.2 1 1 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.25 001166202.1_39522001_1 - 1.7 8.9 8.3 7.2 6.9 8.3 2.1 1 1 0 1 1 1 0 EGF-like domain WH1 PF00568.21 001131690.1_43524001_3 - 2.4e-34 117.5 0.2 4.3e-34 116.7 0.2 1.4 1 0 0 1 1 1 1 WH1 domain GAS PF13851.4 001131690.1_43524001_3 - 2.6e-05 23.6 26.7 2.6e-05 23.6 26.7 1.7 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding HMMR_N PF15905.3 001131690.1_43524001_3 - 0.0012 18.3 23.8 0.0012 18.3 23.8 1.7 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF812 PF05667.9 001131690.1_43524001_3 - 0.065 12.0 25.0 0.11 11.2 25.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.7 001131690.1_43524001_3 - 0.07 13.3 21.7 0.032 14.4 6.8 3.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.10 001131690.1_43524001_3 - 0.077 11.0 20.7 0.079 11.0 18.4 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1664 PF07889.10 001131690.1_43524001_3 - 0.097 12.5 15.9 1.4 8.8 10.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.4 001131690.1_43524001_3 - 0.14 11.4 15.0 0.27 10.4 15.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.9 001131690.1_43524001_3 - 0.51 8.7 30.4 0.0073 14.8 23.2 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlgM PF04316.11 001131690.1_43524001_3 - 0.68 10.2 4.7 0.68 10.2 0.9 2.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Nsp1_C PF05064.11 001131690.1_43524001_3 - 0.76 9.5 24.9 2.8 7.6 12.6 2.4 1 1 1 2 2 2 0 Nsp1-like C-terminal region ATG16 PF08614.9 001131690.1_43524001_3 - 0.77 9.8 42.8 4.9 7.1 24.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.10 001131690.1_43524001_3 - 0.85 8.8 9.3 3.8 6.7 3.0 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FUSC PF04632.10 001131690.1_43524001_3 - 1.2 7.5 9.5 1.7 7.0 9.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family NPV_P10 PF05531.10 001131690.1_43524001_3 - 1.4 9.3 12.0 2.1 8.8 1.5 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.10 001131690.1_43524001_3 - 1.4 8.1 35.0 0.1 11.9 20.5 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 SPT16 PF08644.9 001131690.1_43524001_3 - 2 8.4 9.8 10 6.2 6.2 2.3 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) IFT57 PF10498.7 001131690.1_43524001_3 - 2.2 7.0 28.5 4 6.2 28.5 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.8 001131690.1_43524001_3 - 3.6 7.6 17.7 5.2 7.1 11.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.9 001131690.1_43524001_3 - 4.8 4.9 11.5 7.5 4.2 11.5 1.3 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.6 001131690.1_43524001_3 - 5.7 6.0 27.6 7.2 5.7 15.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.6 001131690.1_43524001_3 - 6.3 6.9 38.1 0.11 12.6 21.3 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.11 001131690.1_43524001_3 - 7.6 4.9 19.4 30 2.9 19.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF489 PF04356.10 001131690.1_43524001_3 - 9.7 6.0 10.0 9 6.1 7.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF489) Med26 PF08711.9 001266853.1_29623001_3 - 3.2e-12 46.2 0.4 3.2e-12 46.2 0.4 2.2 3 0 0 3 3 3 1 TFIIS helical bundle-like domain PARP PF00644.18 001177489.1_49826001_1 - 3.8e-20 72.3 1.2 1.3e-17 64.1 1.2 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.18 001177489.1_49826001_1 - 2.6e-11 43.8 0.7 3.2e-09 37.1 0.2 2.7 2 0 0 2 2 2 2 WWE domain AMPKBI PF04739.13 001131785.1_43529001_3 - 1.9e-26 92.0 3.8 4.2e-26 90.9 3.8 1.6 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.3 001131785.1_43529001_3 - 3.5e-18 65.5 0.0 5.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase STAT_bind PF02864.13 001131222.1_43527001_1 - 8.7e-77 258.2 0.0 8.7e-77 258.2 0.0 2.0 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.18 001131222.1_43527001_1 - 5.1e-56 189.2 17.3 9.1e-56 188.4 17.3 1.4 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.15 001131222.1_43527001_1 - 7.5e-36 123.2 7.1 7.5e-36 123.2 7.1 2.8 3 1 0 3 3 3 1 STAT protein, protein interaction domain SH2 PF00017.22 001131222.1_43527001_1 - 2.7e-13 49.6 0.0 6.3e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain E2R135 PF11570.6 001131222.1_43527001_1 - 0.17 12.0 1.3 0.33 11.1 1.3 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 YojJ PF10372.7 001131222.1_43527001_1 - 1.1 9.3 5.8 1.7 8.7 0.4 2.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus RecG_N PF17190.2 001131222.1_43527001_1 - 7.8 7.2 9.2 2.9 8.5 0.2 3.6 3 1 0 3 3 3 0 RecG N-terminal helical domain DUF1664 PF07889.10 001131222.1_43527001_1 - 9.6 6.1 7.2 24 4.8 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Ku_N PF03731.13 001190185.1_49825001_3 - 2.9e-72 242.9 0.6 6.8e-72 241.6 0.5 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.14 001190185.1_49825001_3 - 1.4e-49 168.4 0.4 2.3e-49 167.7 0.4 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.12 001190185.1_49825001_3 - 5.4e-26 91.0 0.5 1.8e-25 89.3 0.5 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.25 001190185.1_49825001_3 - 9.9e-06 25.1 0.1 2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 SAP domain SAP30_Sin3_bdg PF13867.4 001190185.1_49825001_3 - 0.0016 18.6 0.0 0.0084 16.3 0.0 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 ocr PF08684.8 001190185.1_49825001_3 - 0.011 16.1 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 DNA mimic ocr NpwBP PF12622.5 001190185.1_49825001_3 - 0.36 11.6 0.1 0.36 11.6 0.1 2.4 3 0 0 3 3 3 0 mRNA biogenesis factor Malic_M PF03949.13 001135220.1_39527001_1 - 9.2e-104 346.1 0.3 1.2e-103 345.8 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.17 001135220.1_39527001_1 - 1.1e-78 263.0 0.0 1.6e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain HCO3_cotransp PF00955.19 001315666.1_49829001_2 - 4.3e-223 741.7 6.6 5.3e-223 741.4 6.6 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.11 001315666.1_49829001_2 - 9.5e-104 346.8 0.0 1.5e-103 346.2 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Xan_ur_permease PF00860.18 001315666.1_49829001_2 - 0.0099 14.5 8.0 0.023 13.3 0.5 2.3 2 0 0 2 2 2 2 Permease family 7tm_1 PF00001.19 001177488.1_49823001_1 - 1.8e-37 128.9 10.7 2.6e-37 128.4 10.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001177488.1_49823001_1 - 1.7e-05 24.6 11.8 2.7e-05 23.9 11.8 1.3 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.7 001177488.1_49823001_1 - 2.6e-05 23.6 13.6 3.8e-05 23.1 13.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001177488.1_49823001_1 - 5.6e-05 22.5 14.9 5.6e-05 22.5 14.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DPM3 PF08285.9 001177488.1_49823001_1 - 3.2 7.8 7.5 0.45 10.6 2.0 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Glyco_transf_7N PF13733.4 001246211.1_39524001_2 - 1.5e-59 199.3 0.1 2.1e-59 198.9 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.12 001246211.1_39524001_2 - 2.5e-29 100.6 0.1 4.5e-29 99.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.7 001246211.1_39524001_2 - 0.0032 16.9 0.0 0.008 15.5 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase like family 2 MACPF PF01823.17 001305924.1_29725001_1 - 1.5e-38 132.9 0.0 1.9e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 MAC/Perforin domain C2 PF00168.28 001305924.1_29725001_1 - 9.6e-10 38.5 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain Lipocalin PF00061.21 001025229.1_49822001_3 - 1e-27 97.0 1.6 1.3e-27 96.6 1.6 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001025229.1_49822001_3 - 7.7e-07 29.0 1.2 9.9e-07 28.6 1.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Myosin_N PF02736.17 001025229.1_49822001_3 - 1.8 8.3 5.8 7.4 6.3 0.2 2.7 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain Gla PF00594.18 001244836.1_49824001_2 - 4.3e-19 68.3 4.0 4.3e-19 68.3 4.0 1.7 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Guanylate_kin PF00625.19 001173051.1_09924001_1 - 1.4e-49 168.2 0.1 2.7e-49 167.2 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.6 001173051.1_09924001_1 - 2.5e-22 78.6 6.2 2.5e-22 78.6 6.2 2.3 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.26 001173051.1_09924001_1 - 0.0013 18.2 0.1 0.0042 16.5 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.15 001173051.1_09924001_1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_9 PF14604.4 001173051.1_09924001_1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain IL8 PF00048.18 001305888.1_29723001_1 - 1.2e-12 47.6 1.5 2.1e-12 46.9 1.5 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like zf-C4 PF00105.16 001130241.2_49827001_1 - 2.5e-27 95.0 16.8 4.6e-27 94.1 16.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001130241.2_49827001_1 - 3.7e-16 59.2 0.1 7.7e-16 58.2 0.1 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SAM_2 PF07647.15 001277956.1_29629001_3 - 4.9e-22 77.7 0.3 1.9e-07 30.9 0.0 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001277956.1_29629001_3 - 9.8e-22 77.1 2.6 6.2e-11 42.4 0.2 4.6 5 0 0 5 5 5 3 SAM domain (Sterile alpha motif) DUF745 PF05335.11 001277956.1_29629001_3 - 0.0031 17.2 18.1 0.0031 17.2 18.1 4.3 3 2 2 5 5 5 1 Protein of unknown function (DUF745) 7tm_1 PF00001.19 001135969.1_22423001_1 - 8.4e-51 172.6 18.5 1.7e-50 171.6 18.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001135969.1_22423001_1 - 9e-09 35.0 15.3 1.1e-08 34.6 15.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.7 001135969.1_22423001_1 - 0.00076 18.7 11.5 0.0015 17.8 1.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.7 001135969.1_22423001_1 - 0.12 11.5 10.0 0.0084 15.3 4.7 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF1240 PF06836.10 001135969.1_22423001_1 - 0.61 10.5 8.1 1.5 9.2 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1240) Acatn PF13000.5 001244245.1_49825001_3 - 3e-121 405.5 14.2 6e-73 246.1 7.1 3.0 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Pkinase_Tyr PF07714.15 001131787.1_43529001_2 - 4.3e-92 307.9 0.0 6.5e-92 307.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001131787.1_43529001_2 - 1e-38 133.1 0.0 1.7e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.18 001131787.1_43529001_2 - 1.7e-32 112.3 26.9 1.7e-32 112.3 26.9 1.9 2 0 0 2 2 2 1 Furin-like cysteine rich region Recep_L_domain PF01030.22 001131787.1_43529001_2 - 4.3e-29 100.8 0.4 8.5e-29 99.8 0.4 1.5 1 0 0 1 1 1 1 Receptor L domain fn3 PF00041.19 001131787.1_43529001_2 - 6.6e-19 67.9 8.8 3.2e-05 24.1 0.1 4.8 4 0 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.4 001131787.1_43529001_2 - 0.0071 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF4476 PF14771.4 001131787.1_43529001_2 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) GF_recep_IV PF14843.4 001131787.1_43529001_2 - 4 7.1 29.9 3 7.5 17.5 2.7 1 1 1 2 2 2 0 Growth factor receptor domain IV Gal-bind_lectin PF00337.20 001142827.1_49822001_1 - 3.2e-73 243.5 0.1 2.9e-38 130.3 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin WIF PF02019.16 001142827.1_49822001_1 - 0.00059 19.4 0.0 0.026 14.1 0.0 2.4 2 0 0 2 2 2 2 WIF domain Glyco_transf_29 PF00777.16 001267880.1_39524001_3 - 2e-34 119.0 0.0 4e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Ldh_1_C PF02866.16 001324543.1_32323001_3 - 4.1e-56 189.4 0.0 8.5e-56 188.3 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.21 001324543.1_32323001_3 - 2.3e-47 160.5 0.0 3.3e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.22 001324543.1_32323001_3 - 0.00024 21.4 0.0 0.0035 17.6 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.17 001324543.1_32323001_3 - 0.0084 15.3 0.2 0.097 11.9 0.1 2.4 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.18 001324543.1_32323001_3 - 0.024 14.7 0.0 0.067 13.2 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.17 001324543.1_32323001_3 - 0.028 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.4 001324543.1_32323001_3 - 0.065 13.0 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding Ras PF00071.20 001127282.1_39522001_1 - 1.4e-41 141.6 0.0 1.8e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001127282.1_39522001_1 - 2.5e-16 59.8 0.0 3.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001127282.1_39522001_1 - 9.5e-07 28.3 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001127282.1_39522001_1 - 3.5e-05 23.6 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.21 001127282.1_39522001_1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.4 001127282.1_39522001_1 - 0.0041 17.4 0.1 0.0075 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 001127282.1_39522001_1 - 0.027 14.6 0.0 0.56 10.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.4 001127282.1_39522001_1 - 0.039 14.0 0.1 0.063 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.25 001127282.1_39522001_1 - 0.046 13.1 0.0 0.28 10.6 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.10 001127282.1_39522001_1 - 0.055 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.8 001127282.1_39522001_1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2048 PF09752.7 001159805.1_43527001_1 - 1.1e-132 442.4 0.0 1.4e-132 442.0 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 DUF2048 PF09752.7 001159805.1_43527001_2 - 2.2e-12 46.6 0.0 3.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Abhydrolase domain containing 18 TIR PF01582.18 001135060.2_39525001_2 - 8.9e-26 90.6 0.3 2e-25 89.5 0.3 1.6 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001135060.2_39525001_2 - 3.5e-21 74.6 40.0 2.5e-09 36.6 6.2 7.3 3 3 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.5 001135060.2_39525001_2 - 3.6e-16 58.8 49.7 1.8e-05 24.8 0.3 8.8 7 2 2 9 9 9 4 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001135060.2_39525001_2 - 2.6e-12 46.9 0.0 4.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001135060.2_39525001_2 - 1.4e-06 27.8 11.3 0.037 13.4 0.1 3.7 3 0 0 3 3 3 3 Leucine-rich repeat LRRCT PF01463.22 001135060.2_39525001_2 - 0.00037 20.7 0.0 0.0019 18.5 0.0 2.4 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain TIR-like PF10137.7 001135060.2_39525001_2 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain LRR_6 PF13516.4 001135060.2_39525001_2 - 0.25 11.4 40.6 1.3 9.1 0.1 11.0 12 0 0 12 12 12 0 Leucine Rich repeat LRR_1 PF00560.31 001135060.2_39525001_2 - 0.41 11.2 43.8 3.6 8.3 0.3 11.2 10 2 1 11 11 11 0 Leucine Rich Repeat PTPA PF03095.13 001131523.1_43526001_2 - 1.2e-100 336.7 0.0 1.1e-92 310.5 0.0 2.0 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein TPR_1 PF00515.26 001244392.1_49825001_3 - 2.1e-27 93.6 4.4 7.9e-10 38.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat SGTA_dimer PF16546.3 001244392.1_49825001_3 - 5.6e-21 74.0 0.0 1.1e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.15 001244392.1_49825001_3 - 1.6e-17 62.0 5.0 1.9e-06 27.4 0.1 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.4 001244392.1_49825001_3 - 2.7e-17 61.4 3.5 5.4e-08 32.3 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.4 001244392.1_49825001_3 - 2.4e-15 55.8 6.5 4.1e-06 26.2 0.2 3.8 2 1 2 4 4 4 3 TPR repeat TPR_17 PF13431.4 001244392.1_49825001_3 - 2.6e-12 46.1 2.8 1.9e-06 27.7 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.4 001244392.1_49825001_3 - 3.2e-11 42.3 0.3 0.00056 19.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.4 001244392.1_49825001_3 - 8.2e-09 35.4 0.0 0.0021 18.6 0.0 4.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.4 001244392.1_49825001_3 - 5.1e-08 32.4 4.0 0.01 15.6 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.4 001244392.1_49825001_3 - 1.5e-07 31.7 0.4 4.1e-05 23.9 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.4 001244392.1_49825001_3 - 1.8e-07 31.6 0.4 1.8e-05 25.2 0.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.4 001244392.1_49825001_3 - 2.1e-06 27.8 1.2 2.1e-06 27.8 1.2 2.6 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.4 001244392.1_49825001_3 - 0.00019 21.4 0.1 0.01 15.8 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001244392.1_49825001_3 - 0.0012 18.7 1.0 0.63 10.0 0.1 2.9 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.10 001244392.1_49825001_3 - 0.0012 18.5 0.6 1.1 8.8 0.1 2.6 2 1 0 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 NARP1 PF12569.6 001244392.1_49825001_3 - 0.0043 15.9 0.6 1.1 8.0 0.3 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.4 001244392.1_49825001_3 - 0.013 16.0 1.1 0.45 11.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.4 001244392.1_49825001_3 - 0.038 13.1 0.0 2.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.10 001244392.1_49825001_3 - 0.088 12.7 0.6 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) BTAD PF03704.15 001244392.1_49825001_3 - 0.11 12.8 0.8 1 9.6 0.8 2.2 1 1 0 1 1 1 0 Bacterial transcriptional activator domain XPC-binding PF09280.9 001244392.1_49825001_3 - 0.58 9.8 8.9 3.1 7.5 4.0 2.6 2 0 0 2 2 2 0 XPC-binding domain MIT PF04212.16 001244392.1_49825001_3 - 6.7 6.7 7.5 56 3.8 0.0 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SDF PF00375.16 001289944.1_49825001_3 - 1.9e-119 399.0 25.2 2.5e-119 398.7 25.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MT PF12777.5 001289944.1_49825001_3 - 0.012 14.5 0.1 0.021 13.7 0.1 1.4 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor DUF2207 PF09972.7 001289944.1_49825001_3 - 0.056 12.1 5.3 0.18 10.4 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Pex24p PF06398.9 001289944.1_49825001_3 - 8.1 5.2 7.1 0.86 8.4 0.1 2.4 2 1 1 3 3 3 0 Integral peroxisomal membrane peroxin Copine PF07002.14 001143703.1_49824001_3 - 5.2e-86 287.5 0.0 8.9e-86 286.7 0.0 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.28 001143703.1_49824001_3 - 2.4e-23 82.3 0.0 1.4e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.7 001143703.1_49824001_3 - 1e-05 25.6 0.0 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.26 001143703.1_49824001_3 - 0.0037 17.4 0.0 0.0083 16.3 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain ER_lumen_recept PF00810.16 001244970.1_49824001_2 - 5.3e-52 176.4 9.6 9.8e-52 175.6 9.6 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.12 001244970.1_49824001_2 - 0.45 10.2 10.1 0.28 10.9 0.2 3.2 3 0 0 3 3 3 0 PQ loop repeat Cation_efflux PF01545.19 001137632.1_49824001_1 - 2e-31 109.1 6.6 2.5e-31 108.8 6.6 1.1 1 0 0 1 1 1 1 Cation efflux family XPA_C PF05181.10 001137632.1_49824001_1 - 0.00055 19.7 0.1 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 XPA protein C-terminus IncA PF04156.12 001137632.1_49824001_1 - 0.012 15.2 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 IncA protein RapA_C PF12137.6 001137632.1_49824001_1 - 0.022 13.7 0.7 0.04 12.8 0.7 1.4 1 1 0 1 1 1 0 RNA polymerase recycling family C-terminal ZT_dimer PF16916.3 001137632.1_49824001_1 - 0.1 12.6 1.7 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 Dimerisation domain of Zinc Transporter Deltameth_res PF16020.3 001137632.1_49824001_1 - 0.56 10.0 2.0 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 Deltamethrin resistance STAT_bind PF02864.13 001314278.1_09025001_1 - 5.6e-76 255.6 0.0 5.6e-76 255.6 0.0 2.0 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.18 001314278.1_09025001_1 - 4.5e-56 189.4 18.1 8.9e-56 188.4 18.1 1.5 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.15 001314278.1_09025001_1 - 8.3e-38 129.5 7.9 8.3e-38 129.5 7.9 3.4 3 1 1 4 4 3 1 STAT protein, protein interaction domain SH2 PF00017.22 001314278.1_09025001_1 - 1.4e-13 50.5 0.0 3.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain E2R135 PF11570.6 001314278.1_09025001_1 - 0.1 12.8 1.1 0.2 11.8 1.1 1.4 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 YojJ PF10372.7 001314278.1_09025001_1 - 0.23 11.5 7.1 1.1 9.3 0.4 2.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Syntaxin-6_N PF09177.9 001314278.1_09025001_1 - 0.49 10.9 7.6 0.43 11.0 2.4 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.8 001314278.1_09025001_1 - 1.2 9.2 12.7 0.91 9.6 7.4 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RecG_N PF17190.2 001314278.1_09025001_1 - 1.3 9.7 10.1 1.9 9.2 0.2 3.8 3 1 0 3 3 3 0 RecG N-terminal helical domain Baculo_PEP_C PF04513.10 001314278.1_09025001_1 - 1.3 8.9 5.3 1.3 8.9 3.4 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MerR-DNA-bind PF09278.9 001314278.1_09025001_1 - 3.5 8.1 14.8 3.1 8.3 0.6 3.9 4 0 0 4 4 4 0 MerR, DNA binding DUF1664 PF07889.10 001314278.1_09025001_1 - 3.8 7.4 9.3 6.1 6.7 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF2408 PF10303.7 001314278.1_09025001_1 - 4.1 7.8 7.7 4.1 7.8 1.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF342 PF03961.11 001314278.1_09025001_1 - 7.1 5.0 8.7 0.45 8.9 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Tropomyosin_1 PF12718.5 001314278.1_09025001_1 - 7.7 6.5 11.6 1 9.4 6.3 2.0 2 0 0 2 2 2 0 Tropomyosin like Lectin_C PF00059.19 001190251.1_49822001_2 - 1.9e-18 67.0 5.5 2.9e-18 66.4 5.5 1.3 1 0 0 1 1 1 1 Lectin C-type domain NGF PF00243.16 001285715.1_09022001_3 - 1.8e-51 173.0 2.0 2.8e-51 172.4 2.0 1.3 1 0 0 1 1 1 1 Nerve growth factor family Spaetzle PF16077.3 001285715.1_09022001_3 - 0.00047 20.4 0.2 0.0007 19.9 0.2 1.2 1 0 0 1 1 1 1 Spaetzle Zip PF02535.20 001163599.1_39522001_1 - 8.9e-52 176.2 9.6 5.9e-39 134.1 2.0 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Glyco_hydro_20 PF00728.20 001126343.1_39524001_1 - 4.5e-84 282.7 0.0 7.3e-84 282.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.4 001126343.1_39524001_1 - 7.6e-20 71.8 0.0 1.2e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.13 001126343.1_39524001_1 - 0.095 13.4 0.0 0.24 12.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 CDI PF02234.17 001161880.1_39521001_1 - 2.8e-20 72.1 0.2 4.2e-20 71.6 0.2 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor PAP2 PF01569.19 001266056.1_29623001_3 - 7.4e-21 74.2 1.8 1.5e-20 73.3 1.8 1.5 1 0 0 1 1 1 1 PAP2 superfamily Mito_carr PF00153.25 001142895.1_39523001_1 - 2e-49 165.3 7.3 4.8e-19 67.9 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.23 001166044.1_49823001_1 - 3.1e-70 236.4 0.0 3.7e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001166044.1_49823001_1 - 1.1e-32 113.2 0.0 1.5e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001166044.1_49823001_1 - 7.6e-05 22.0 0.1 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Arf PF00025.19 001252214.1_49827001_1 - 1.6e-45 154.5 0.1 2.3e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.20 001252214.1_49827001_1 - 6e-18 64.8 0.0 8e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001252214.1_49827001_1 - 1.7e-15 57.2 0.0 2.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.10 001252214.1_49827001_1 - 3.2e-09 36.3 0.0 4.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001252214.1_49827001_1 - 2.6e-06 26.9 0.0 3.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.18 001252214.1_49827001_1 - 1.4e-05 24.3 0.2 0.0016 17.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.21 001252214.1_49827001_1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase VirE PF05272.9 001252214.1_49827001_1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Ribosomal_L7Ae PF01248.24 001243673.1_49823001_3 - 1.2e-10 40.9 0.0 2.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.4 001243673.1_49823001_3 - 0.069 12.9 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain RRM_1 PF00076.20 001077223.1_49822001_1 - 7.8e-20 70.3 0.0 1.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.7 001077223.1_49822001_1 - 0.069 11.9 12.9 0.087 11.5 12.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.7 001077223.1_49822001_1 - 0.95 7.8 6.2 0.99 7.7 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Presenilin PF01080.15 001077223.1_49822001_1 - 2.2 6.8 6.8 2.6 6.6 6.8 1.1 1 0 0 1 1 1 0 Presenilin SOBP PF15279.4 001077223.1_49822001_1 - 2.4 8.5 11.9 4.4 7.6 11.9 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein RRM_1 PF00076.20 001195585.1_29625001_1 - 2.9e-14 52.5 0.0 6.6e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.20 001163601.1_39522001_1 - 1.1e-63 215.4 13.5 1.6e-42 145.8 8.2 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF2461 PF09365.8 001163601.1_39522001_1 - 0.04 13.7 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Prenyltrans PF00432.19 001261210.1_29624001_1 - 1.8e-39 133.0 6.4 2.3e-09 36.7 0.0 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat DUF2374 PF09574.8 001261210.1_29624001_3 - 0.1 12.3 0.1 0.28 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) DUF1289 PF06945.11 001261210.1_29624001_3 - 0.15 11.7 2.5 0.3 10.8 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Glycos_transf_2 PF00535.24 001318076.1_39525001_1 - 1.5e-16 60.5 0.0 2.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_5 PF13712.4 001318076.1_39525001_1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family Carb_anhydrase PF00194.19 001195417.1_29623001_2 - 1.6e-99 332.4 0.0 1.9e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Peptidase_C2 PF00648.19 001112817.1_39525001_1 - 2.3e-128 427.3 0.0 4.7e-128 426.2 0.0 1.6 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.20 001112817.1_39525001_1 - 3.2e-55 186.2 0.0 5e-55 185.5 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.30 001112817.1_39525001_1 - 5.3e-10 38.0 1.8 0.011 15.1 0.0 4.9 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.4 001112817.1_39525001_1 - 1e-09 37.4 0.4 0.035 13.9 0.0 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.4 001112817.1_39525001_1 - 4.5e-09 35.8 1.5 2e-07 30.5 0.2 3.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.4 001112817.1_39525001_1 - 5.4e-05 23.4 7.3 0.95 9.9 1.3 4.9 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.4 001112817.1_39525001_1 - 0.08 12.4 1.3 2.2 7.8 0.1 3.3 3 0 0 3 3 3 0 EF hand Sarcoglycan_1 PF04790.11 001114287.1_49822001_1 - 1.3e-62 211.4 0.3 1.6e-62 211.1 0.3 1.1 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein Sec62 PF03839.14 001114287.1_49822001_1 - 5 6.4 4.4 11 5.3 4.4 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Vps26 PF03643.13 001133528.1_43526001_2 - 4.3e-105 350.5 3.8 5.9e-105 350.1 3.8 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Vps26 PF03643.13 001133528.1_43526001_3 - 1.4e-08 34.0 0.0 2.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Kunitz_BPTI PF00014.21 001131209.1_43526001_1 - 2.4e-52 174.8 50.4 6.4e-18 64.6 9.6 3.7 4 0 0 4 4 4 3 Kunitz/Bovine pancreatic trypsin inhibitor domain CRAL_TRIO PF00650.18 001198882.1_39523001_3 - 9.7e-30 103.2 0.0 1.3e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.13 001198882.1_39523001_3 - 5.3e-05 23.2 3.4 0.00015 21.7 3.4 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Filament PF00038.19 001173074.1_09923001_1 - 1e-47 163.1 20.5 1.3e-47 162.8 20.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein MCPVI PF02993.12 001173074.1_09923001_1 - 0.1 12.3 1.3 0.26 11.0 0.8 2.0 1 1 0 1 1 1 0 Minor capsid protein VI Uso1_p115_C PF04871.11 001173074.1_09923001_1 - 6.3 7.1 26.9 0.29 11.4 12.1 2.9 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region IL8 PF00048.18 001305905.1_29721001_1 - 1.1e-23 83.0 3.0 1.3e-23 82.7 3.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF4725 PF15854.3 001305905.1_29721001_1 - 0.029 14.5 0.3 0.036 14.2 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4725) Bcl-2 PF00452.17 001314213.1_09022001_1 - 2.1e-32 111.5 0.1 2.9e-32 111.1 0.1 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.15 001314213.1_09022001_1 - 4.6e-14 51.7 0.3 9.1e-14 50.8 0.3 1.5 1 0 0 1 1 1 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.4 001314213.1_09022001_1 - 0.0037 17.8 0.0 0.0053 17.3 0.0 1.2 1 0 0 1 1 1 1 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Integrin_alpha2 PF08441.10 213998.1_49827001_3 - 9.8e-119 397.1 0.6 1.2e-118 396.9 0.6 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 213998.1_49827001_3 - 2.7e-21 75.2 18.8 3.3e-09 36.6 0.0 4.7 5 0 0 5 5 5 3 FG-GAP repeat VCBS PF13517.4 213998.1_49827001_3 - 9.7e-13 48.4 0.6 6.3e-06 26.6 0.4 3.7 3 1 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 213998.1_49827001_3 - 4.9e-06 26.0 0.3 1.3e-05 24.6 0.3 1.8 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region Copine PF07002.14 001161890.1_39524001_1 - 2.6e-85 285.2 0.0 5.9e-85 284.0 0.0 1.6 2 0 0 2 2 2 1 Copine C2 PF00168.28 001161890.1_39524001_1 - 1.3e-24 86.3 0.0 7.8e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.7 001161890.1_39524001_1 - 2.5e-05 24.4 0.0 4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.26 001161890.1_39524001_1 - 0.0027 17.9 0.0 0.0071 16.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Cys_knot PF00007.20 001113057.1_49821001_1 - 1.3e-06 28.5 11.1 1.9e-06 28.0 11.1 1.3 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.13 001113057.1_49821001_1 - 6.5e-06 26.0 9.4 8.1e-06 25.7 9.4 1.1 1 0 0 1 1 1 1 DAN domain FKBP_C PF00254.26 001244157.2_49823001_2 - 2.1e-31 108.0 0.0 3.5e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.4 001132600.1_43527001_3 - 3.3e-10 39.3 12.8 0.0022 17.5 0.1 5.3 5 0 0 5 5 5 4 TPR repeat TPR_19 PF14559.4 001132600.1_43527001_3 - 5.3e-09 36.3 17.6 0.00056 20.2 0.0 5.9 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.15 001132600.1_43527001_3 - 6.9e-09 35.0 27.6 0.007 16.3 0.1 8.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.4 001132600.1_43527001_3 - 9.4e-08 32.1 13.5 0.0003 20.9 0.8 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.26 001132600.1_43527001_3 - 1.7e-07 30.7 30.7 0.024 14.3 0.5 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.4 001132600.1_43527001_3 - 3.6e-07 30.3 10.1 0.039 14.6 0.0 7.2 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.4 001132600.1_43527001_3 - 1.4e-06 28.1 15.3 0.19 12.0 0.2 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.4 001132600.1_43527001_3 - 2.6e-05 23.9 23.4 0.15 12.2 0.3 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.4 001132600.1_43527001_3 - 0.0017 18.1 6.0 0.089 12.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.4 001132600.1_43527001_3 - 0.0026 16.9 0.4 0.11 11.5 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat RPT PF13446.4 001132600.1_43527001_3 - 0.25 11.2 0.7 4.8 7.0 0.1 2.5 2 0 0 2 2 2 0 A repeated domain in UCH-protein TPR_6 PF13174.4 001132600.1_43527001_3 - 0.81 10.3 7.5 35 5.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.4 001132600.1_43527001_3 - 1.3 8.9 5.4 53 3.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001132600.1_43527001_3 - 3.5 7.7 0.0 3.5 7.7 0.0 5.4 4 2 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.4 001132600.1_43527001_3 - 6.1 7.5 7.3 12 6.6 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat NAD_Gly3P_dh_N PF01210.21 001190240.1_49824001_1 - 6.4e-54 182.0 0.1 1.9e-53 180.5 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.12 001190240.1_49824001_1 - 4.7e-49 166.2 0.1 7.3e-49 165.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 2-Hacid_dh_C PF02826.17 001190240.1_49824001_1 - 0.022 14.0 0.1 0.04 13.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.15 001190240.1_49824001_1 - 0.053 14.0 1.3 5.9 7.4 0.0 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent MMR_HSR1 PF01926.21 001128478.1_49824001_1 - 9.8e-14 51.3 0.0 2.6e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.16 001128478.1_49824001_1 - 7e-05 22.3 0.1 0.00043 19.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.14 001128478.1_49824001_1 - 0.0035 17.1 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.21 001128478.1_49824001_1 - 0.063 13.2 0.4 0.063 13.2 0.4 2.9 3 1 1 4 4 4 0 Dynamin family Ig_2 PF13895.4 001271648.2_29622001_1 - 6.3e-24 84.0 0.6 1.2e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001271648.2_29622001_1 - 2.4e-15 56.8 0.2 5.4e-07 30.0 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001271648.2_29622001_1 - 3.4e-09 36.6 1.6 0.0012 18.8 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.3 001271648.2_29622001_1 - 9.6e-07 28.9 0.0 0.0026 18.0 0.0 2.2 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain I-set PF07679.14 001271648.2_29622001_1 - 6e-05 22.9 0.1 0.41 10.6 0.0 3.3 2 2 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.15 001271648.2_29622001_1 - 8.6e-05 22.5 2.2 4.5 7.3 0.0 3.9 2 2 2 4 4 4 2 Immunoglobulin V-set domain Ig_5 PF16681.3 001271648.2_29622001_1 - 0.00035 20.8 0.0 0.01 16.1 0.0 2.2 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF3827 PF12877.5 001271648.2_29622001_1 - 0.0032 15.8 0.4 0.0043 15.4 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) TMEM154 PF15102.4 001271648.2_29622001_1 - 0.014 15.1 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family CD34_antigen PF06365.10 001271648.2_29622001_1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Adeno_E3_CR2 PF02439.13 001271648.2_29622001_1 - 0.026 14.2 6.7 0.056 13.1 6.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ECSCR PF15820.3 001271648.2_29622001_1 - 0.032 13.9 0.6 0.072 12.8 0.3 1.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator RCR PF12273.6 001271648.2_29622001_1 - 0.067 13.7 0.7 6.2 7.4 0.0 3.0 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red 7tm_1 PF00001.19 001009248.1_22423001_1 - 2.5e-46 158.0 14.8 4.4e-46 157.2 14.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001009248.1_22423001_1 - 0.00013 21.3 12.7 0.00018 20.9 12.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001009248.1_22423001_1 - 0.041 13.1 9.4 0.045 12.9 8.5 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srab PF10292.7 001009248.1_22423001_1 - 0.27 10.0 9.1 0.13 11.0 2.9 2.4 1 1 1 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Pkinase PF00069.23 001143704.1_49824001_3 - 2.7e-66 223.5 0.0 3.2e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001143704.1_49824001_3 - 6.1e-32 110.8 0.0 8.1e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001143704.1_49824001_3 - 1.2e-07 31.2 0.1 0.0003 20.1 0.0 2.1 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.20 001143704.1_49824001_3 - 0.026 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family TERB2 PF15101.4 001193506.1_29622001_2 - 6.8e-88 294.0 0.0 8.3e-88 293.7 0.0 1.0 1 0 0 1 1 1 1 Telomere-associated protein TERB2 PI3K_P85_iSH2 PF16454.3 001193506.1_29622001_2 - 0.043 13.3 0.2 0.08 12.4 0.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4219 PF13961.4 001193506.1_29622001_3 - 0.017 14.8 0.1 0.041 13.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) SDF PF00375.16 001289946.1_49824001_3 - 2.1e-105 352.8 29.5 2.3e-80 270.4 14.9 2.1 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family DUF2207 PF09972.7 001289946.1_49824001_3 - 0.15 10.6 4.1 0.089 11.4 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) IL8 PF00048.18 001040290.1_39522001_1 - 2e-18 66.1 0.0 2.9e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like G-alpha PF00503.18 001162566.1_39523001_1 - 4.9e-125 417.2 1.7 5.8e-125 417.0 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001162566.1_39523001_1 - 1.2e-17 63.8 0.1 1.2e-12 47.6 0.1 2.8 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001162566.1_39523001_1 - 1.4e-05 24.5 1.1 0.045 13.0 0.6 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.11 001162566.1_39523001_1 - 9.2e-05 22.5 0.1 0.65 10.1 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DUF261 PF03196.11 001162566.1_39523001_1 - 0.024 14.6 0.9 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF261 AAA_16 PF13191.4 001162566.1_39523001_1 - 0.03 14.5 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.20 001162566.1_39523001_1 - 0.042 13.3 1.7 3.7 7.0 1.0 2.6 2 1 0 2 2 2 0 Ras family TniB PF05621.9 001162566.1_39523001_1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.4 001162566.1_39523001_1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.20 001161872.1_39522001_1 - 1.6e-35 121.9 0.0 2.3e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001161872.1_39522001_1 - 4e-11 43.1 0.0 6.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001161872.1_39522001_1 - 1.7e-05 24.2 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001161872.1_39522001_1 - 0.007 15.8 0.0 0.053 12.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001161872.1_39522001_1 - 0.044 13.1 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.9 001161872.1_39522001_1 - 0.16 11.0 0.0 0.36 9.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF1992 PF09350.8 001131425.1_43525001_1 - 6.4e-22 77.4 0.0 2e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DnaJ PF00226.29 001131425.1_43525001_1 - 3.5e-12 46.1 3.9 6.5e-11 42.1 0.1 3.4 3 0 0 3 3 3 1 DnaJ domain AAA_23 PF13476.4 001131425.1_43525001_1 - 0.00056 20.4 14.6 0.00056 20.4 14.6 3.4 2 1 0 2 2 2 1 AAA domain DDHD PF02862.15 001131425.1_43525001_1 - 0.0024 17.9 4.3 0.0024 17.9 4.3 2.8 3 0 0 3 3 3 1 DDHD domain Zip PF02535.20 001131425.1_43525001_1 - 0.018 14.1 5.4 0.031 13.4 5.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.4 001131425.1_43525001_1 - 0.034 12.5 0.2 0.034 12.5 0.2 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Afi1 PF07792.10 001131425.1_43525001_2 - 0.00086 19.7 2.3 0.0013 19.1 2.3 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.20 001131425.1_43525001_2 - 0.062 12.4 8.4 0.083 12.0 8.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Zip PF02535.20 001131425.1_43525001_3 - 0.056 12.5 10.5 0.072 12.2 10.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.4 001131425.1_43525001_3 - 0.78 8.0 3.7 0.97 7.7 3.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MIP-T3 PF10243.7 001131425.1_43525001_3 - 2.1 6.9 49.0 2.5 6.6 49.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOXp PF12336.6 001123197.1_49822001_1 - 4.6e-38 130.0 4.1 4.6e-38 130.0 4.1 2.5 4 0 0 4 4 4 1 SOX transcription factor HMG_box PF00505.17 001123197.1_49822001_1 - 3e-27 94.7 2.6 4.8e-27 94.0 2.6 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001123197.1_49822001_1 - 3.8e-11 43.3 1.4 6.4e-11 42.6 1.4 1.4 1 0 0 1 1 1 1 HMG-box domain VCBS PF13517.4 001244956.1_49826001_2 - 0.0013 19.1 0.4 2.6 8.6 0.1 3.1 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.4 001244956.1_49826001_2 - 0.0014 18.1 0.1 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 PQQ-like domain FG-GAP PF01839.21 001244956.1_49826001_2 - 0.041 13.9 0.2 0.041 13.9 0.2 3.3 3 0 0 3 3 3 0 FG-GAP repeat TPPII PF12580.6 001132106.1_43526001_1 - 0.0057 16.0 0.0 0.0078 15.6 0.0 1.1 1 0 0 1 1 1 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.20 001132106.1_43526001_2 - 1.5e-112 375.6 2.8 2.2e-112 375.1 2.8 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.6 001132106.1_43526001_2 - 2.6e-43 147.6 0.0 4.8e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II Tim17 PF02466.17 001244924.1_49822001_2 - 5.3e-08 33.0 4.3 7.7e-08 32.5 4.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3021 PF11457.6 001244924.1_49822001_2 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Gly-zipper_OmpA PF13436.4 001244924.1_49822001_2 - 1.8 8.3 14.8 24 4.7 6.9 3.2 3 0 0 3 3 3 0 Glycine-zipper domain Troponin PF00992.18 001329087.1_37922001_1 - 1.9e-33 115.5 43.2 6.6e-33 113.7 35.7 2.3 1 1 1 2 2 2 2 Troponin DUF4250 PF14056.4 001329087.1_37922001_1 - 0.088 12.6 0.5 0.24 11.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) CBS PF00571.26 001122692.1_39525001_2 - 3.2e-34 117.0 3.3 6.9e-11 42.3 0.1 4.4 4 0 0 4 4 4 4 CBS domain SDF PF00375.16 001261669.1_29629001_2 - 1.6e-131 438.8 29.5 2e-131 438.5 29.5 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family PSP PF04046.14 001190154.1_49826001_3 - 3e-17 62.1 0.1 6.4e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.21 001190154.1_49826001_3 - 3e-05 23.8 3.3 6.7e-05 22.7 3.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Totivirus_coat PF05518.9 001190154.1_49826001_3 - 0.45 8.4 5.4 0.69 7.8 5.4 1.2 1 0 0 1 1 1 0 Totivirus coat protein NYD-SP28_assoc PF14775.4 001190154.1_49826001_3 - 7.1 6.7 7.2 5 7.2 4.5 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain WD40 PF00400.30 001243455.1_49823001_2 - 2.6e-14 53.2 8.4 0.00085 20.0 0.1 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001243455.1_49823001_2 - 1.2e-05 25.4 0.0 0.64 10.2 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.25 001127291.1_39522001_1 - 1.4e-45 153.0 0.2 3.6e-18 65.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.25 001127291.1_39522001_2 - 5e-05 23.0 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial carrier protein RA PF00788.21 001161877.1_39523001_1 - 9.3e-19 67.7 0.1 2.5e-18 66.3 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.3 001161877.1_39523001_1 - 1.1e-18 66.8 6.1 5.7e-18 64.5 4.5 2.4 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain C1_1 PF00130.20 001161877.1_39523001_1 - 1.5e-09 37.5 10.9 2.8e-09 36.6 10.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Mst1_SARAH PF11629.6 001161877.1_39523001_1 - 0.074 13.0 0.7 0.074 13.0 0.7 2.0 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Peptidase_M10 PF00413.22 001166181.1_39524001_1 - 8.1e-59 197.9 0.0 1.4e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.17 001166181.1_39524001_1 - 1.5e-55 184.8 15.6 7.4e-14 51.3 0.2 4.7 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.6 001166181.1_39524001_1 - 1.2e-24 85.9 0.0 2.6e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.16 001166181.1_39524001_1 - 1.6e-11 44.1 0.1 3.8e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.22 001166181.1_39524001_1 - 0.00084 18.9 0.6 0.34 10.4 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.9 001166181.1_39524001_1 - 0.0069 16.3 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M54 Metallopep PF12044.6 001166181.1_39524001_1 - 0.022 13.2 0.0 0.032 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family DUF4953 PF16313.3 001166181.1_39524001_1 - 0.026 13.6 0.1 0.043 12.9 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.4 001166181.1_39524001_1 - 0.066 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like HTH_17 PF12728.5 001166181.1_39524001_1 - 0.081 13.0 0.0 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_M66 PF10462.7 001166181.1_39524001_1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 SKG6 PF08693.8 001166181.1_39524001_1 - 0.15 11.3 3.8 0.34 10.2 3.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Zip PF02535.20 001163600.1_39522001_1 - 2e-57 194.8 16.6 3e-55 187.6 16.6 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF21 PF01595.18 001163600.1_39522001_1 - 0.28 10.8 7.5 0.17 11.4 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 PIG-P PF08510.10 001163600.1_39522001_1 - 0.28 11.0 0.8 7.2 6.4 0.1 2.3 2 0 0 2 2 2 0 PIG-P p450 PF00067.20 001132913.2_43524001_2 - 9e-69 232.2 0.0 2.5e-36 125.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Nup88 PF10168.7 001133241.1_43525001_1 - 0 1027.3 0.0 0 1027.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore component FliJ PF02050.14 001133241.1_43525001_1 - 3.2 7.9 19.2 0.67 10.0 8.7 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Exonuc_VII_L PF02601.13 001133241.1_43525001_1 - 7.3 5.9 9.3 11 5.3 9.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ig_3 PF13927.4 001135962.1_49822001_1 - 4.6e-09 36.6 0.2 1.5e-08 35.0 0.2 1.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 001135962.1_49822001_1 - 1.1e-08 35.0 1.2 0.00076 19.5 0.3 2.4 1 1 1 2 2 2 2 Immunoglobulin V-set domain ig PF00047.23 001135962.1_49822001_1 - 2.1e-07 30.9 0.2 5.9e-07 29.4 0.2 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001135962.1_49822001_1 - 4.1e-06 26.9 0.1 7.3e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ITAM PF02189.13 001135962.1_49822001_1 - 2.4e-05 24.4 0.9 5.1e-05 23.4 0.2 2.0 2 0 0 2 2 2 1 Immunoreceptor tyrosine-based activation motif I-set PF07679.14 001135962.1_49822001_1 - 2.7e-05 24.0 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Trp_leader2 PF08056.9 001135962.1_49822001_1 - 0.041 13.8 0.4 0.088 12.7 0.4 1.5 1 0 0 1 1 1 0 Tryptophan operon leader peptide Ig_4 PF16680.3 001135962.1_49822001_1 - 0.1 12.8 0.6 1.5 9.1 0.6 2.3 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Cofilin_ADF PF00241.18 001261184.1_29627001_1 - 1.5e-28 99.4 1.3 2.3e-28 98.8 1.3 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Neur_chan_LBD PF02931.21 001267876.1_39523001_1 - 3.1e-50 170.5 0.0 5.3e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001267876.1_39523001_1 - 6.9e-48 163.6 1.0 3.5e-47 161.3 1.0 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.7 001267876.1_39523001_1 - 0.79 7.8 4.2 1.1 7.3 4.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MAGE_N PF12440.6 001328309.1_39724001_2 - 2.2e-24 85.8 13.3 3.6e-24 85.1 13.3 1.4 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal MAGE PF01454.17 001328309.1_39724001_2 - 1.6e-16 60.5 0.0 1.1e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 MAGE family Ion_trans_2 PF07885.14 001315680.1_49824001_3 - 5.6e-38 128.6 19.6 2.2e-19 69.0 10.1 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.29 001315680.1_49824001_3 - 3.8e-06 26.2 8.8 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 Ion transport protein adh_short_C2 PF13561.4 001281888.1_40423001_3 - 5.8e-60 202.6 0.0 8.1e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001281888.1_40423001_3 - 5.5e-48 162.9 0.1 7.3e-48 162.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001281888.1_40423001_3 - 2.6e-11 43.6 0.2 3.8e-11 43.1 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001281888.1_40423001_3 - 0.0082 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.13 001281888.1_40423001_3 - 0.014 15.2 0.6 0.028 14.2 0.6 1.4 1 1 0 1 1 1 0 YjeF-related protein N-terminus F420_oxidored PF03807.15 001281888.1_40423001_3 - 0.022 15.2 0.2 0.036 14.5 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.8 001281888.1_40423001_3 - 0.18 11.0 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HA2 PF04408.21 001133228.1_43529001_2 - 1.1e-19 70.5 0.0 1.1e-19 70.5 0.0 4.4 5 1 0 5 5 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.14 001133228.1_43529001_2 - 4.1e-19 68.6 0.0 1.4e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.29 001133228.1_43529001_2 - 1.3e-13 51.1 0.0 2.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.27 001133228.1_43529001_2 - 2.2e-07 30.7 0.0 5.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.4 001133228.1_43529001_2 - 1.6e-05 25.1 0.0 4.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.4 001133228.1_43529001_2 - 0.00057 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.4 001133228.1_43529001_2 - 0.0023 18.1 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.18 001133228.1_43529001_2 - 0.0038 16.2 0.0 0.007 15.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.14 001133228.1_43529001_2 - 0.021 14.2 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.20 001133228.1_43529001_2 - 0.043 12.7 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Flavi_DEAD PF07652.12 001133228.1_43529001_2 - 0.043 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_33 PF13671.4 001133228.1_43529001_2 - 0.14 12.2 0.0 0.14 12.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain CARD PF00619.19 001244277.1_49822001_1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Caspase recruitment domain Melibiase_2 PF16499.3 001126345.1_39523001_1 - 5e-166 551.9 0.0 5.7e-166 551.7 0.0 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.16 001126345.1_39523001_1 - 0.001 17.9 0.1 0.0017 17.2 0.1 1.3 1 0 0 1 1 1 1 Melibiase IRK PF01007.18 001132706.1_43529001_2 - 1.6e-140 467.6 1.1 2.1e-140 467.2 1.1 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.14 001132706.1_43529001_2 - 1.3 9.0 5.3 3.9 7.4 5.4 1.8 1 1 0 1 1 1 0 Ion channel PDEase_I PF00233.17 001131589.1_43529001_1 - 1.2e-80 270.5 4.4 1.9e-80 269.9 4.4 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.10 001131589.1_43529001_1 - 4.6e-31 106.3 0.1 9e-31 105.4 0.1 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal Pkinase PF00069.23 001135310.1_43529001_3 - 4.1e-72 242.6 0.0 5.3e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001135310.1_43529001_3 - 1.2e-33 116.4 0.0 1.7e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001135310.1_43529001_3 - 2.3e-07 30.3 0.0 7.2e-07 28.7 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Pro_isomerase PF00160.19 001243664.1_49823001_3 - 1.5e-42 145.4 0.0 2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RCC1 PF00415.16 001302104.1_40429001_1 - 1.7e-35 121.2 9.7 5.2e-11 42.9 1.5 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.29 001302104.1_40429001_1 - 4.8e-33 113.6 10.1 7.9e-17 61.3 1.3 3.4 2 1 1 3 3 3 2 BTB/POZ domain Ank_5 PF13857.4 001302104.1_40429001_1 - 2.7e-10 40.2 0.0 0.00066 19.8 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001302104.1_40429001_1 - 8.1e-10 39.0 0.0 3.4e-09 37.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001302104.1_40429001_1 - 6.4e-09 36.0 0.0 6.1e-06 26.6 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) RCC1_2 PF13540.4 001302104.1_40429001_1 - 2.1e-08 33.6 11.3 0.0025 17.4 0.1 5.8 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.28 001302104.1_40429001_1 - 1.1e-06 28.7 0.0 0.02 15.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.4 001302104.1_40429001_1 - 4.3e-06 26.5 0.0 0.027 14.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF3342 PF11822.6 001302104.1_40429001_1 - 0.19 11.8 1.7 0.35 11.0 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) adh_short_C2 PF13561.4 001251894.1_39723001_1 - 2.8e-53 180.8 0.0 3.6e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.23 001251894.1_39723001_1 - 5.8e-43 146.5 0.0 7.5e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.8 001251894.1_39723001_1 - 4.3e-05 23.4 1.2 6.9e-05 22.7 1.2 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.13 001251894.1_39723001_1 - 0.095 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus Pkinase PF00069.23 001112693.1_49823001_1 - 1e-53 182.3 0.1 1.5e-53 181.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001112693.1_49823001_1 - 2.4e-53 181.0 0.0 3.7e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Death PF00531.20 001112693.1_49823001_1 - 0.02 14.9 0.0 0.071 13.2 0.0 1.9 1 0 0 1 1 1 0 Death domain 14-3-3 PF00244.18 001315726.1_49822001_3 - 3e-110 366.8 6.4 3.4e-110 366.6 6.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.13 001315726.1_49822001_3 - 0.085 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM AAA_15 PF13175.4 001315726.1_49822001_3 - 0.097 12.1 0.8 0.14 11.6 0.4 1.5 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_C98 PF15499.4 001315726.1_49822001_3 - 0.1 11.9 0.3 0.16 11.2 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Sprouty PF05210.11 001319279.1_39522001_1 - 1.7e-33 115.1 31.1 3e-33 114.4 31.1 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) Mito_carr PF00153.25 001127280.1_39522001_1 - 2.4e-69 229.2 3.4 1.2e-25 89.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.3 001127280.1_39522001_1 - 0.029 13.4 0.2 0.21 10.6 0.1 2.0 2 0 0 2 2 2 0 Fuseless RBD-FIP PF09457.8 001134004.1_43526001_2 - 8.8e-11 41.4 3.5 1.5e-10 40.7 3.5 1.4 1 0 0 1 1 1 1 FIP domain TEA PF01285.16 001142666.1_49823001_2 - 6.7e-27 94.6 0.0 8.8e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 TEA/ATTS domain family TPR_2 PF07719.15 001159796.2_43525001_2 - 9.9e-17 59.5 27.2 0.0004 20.1 0.0 8.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.4 001159796.2_43525001_2 - 1.2e-14 53.0 25.9 0.011 15.8 0.0 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.4 001159796.2_43525001_2 - 1.8e-14 53.9 8.7 3.9e-05 23.9 0.1 4.6 3 1 2 5 5 4 4 Tetratricopeptide repeat TPR_11 PF13414.4 001159796.2_43525001_2 - 6.1e-12 44.9 15.8 0.0017 17.9 0.1 6.5 6 0 0 6 6 6 3 TPR repeat TPR_17 PF13431.4 001159796.2_43525001_2 - 1.7e-11 43.5 19.3 0.019 15.2 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.4 001159796.2_43525001_2 - 1.9e-11 43.6 6.4 0.00098 19.6 0.0 7.9 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.26 001159796.2_43525001_2 - 2e-11 43.1 32.6 0.0019 17.8 0.0 8.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.4 001159796.2_43525001_2 - 2.2e-11 43.8 13.5 3.3e-07 30.3 3.2 4.8 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.4 001159796.2_43525001_2 - 1.4e-10 40.3 3.2 0.0015 18.3 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.4 001159796.2_43525001_2 - 3.3e-08 34.0 0.3 0.021 15.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.4 001159796.2_43525001_2 - 3.8e-06 27.1 6.3 0.028 14.9 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.6 001159796.2_43525001_2 - 6.3e-05 21.9 3.3 0.0015 17.4 0.0 3.6 2 2 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.4 001159796.2_43525001_2 - 7.5e-05 21.9 2.4 0.15 11.2 0.1 4.4 2 1 1 4 4 4 1 Tetratricopeptide repeat Cohesin_load PF10345.7 001159796.2_43525001_2 - 0.00011 20.6 4.2 0.018 13.4 0.0 3.8 3 2 1 4 4 4 1 Cohesin loading factor PUL PF08324.9 001159796.2_43525001_2 - 0.0012 18.1 0.1 0.0027 16.9 0.1 1.5 1 0 0 1 1 1 1 PUL domain TPR_10 PF13374.4 001159796.2_43525001_2 - 0.0043 16.8 10.4 4 7.3 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.8 001159796.2_43525001_2 - 0.014 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.7 001159796.2_43525001_2 - 0.078 12.5 1.4 1.2 8.6 0.1 2.9 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_9 PF13371.4 001159796.2_43525001_2 - 0.094 12.8 3.9 11 6.1 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001159796.2_43525001_2 - 0.16 12.1 11.2 0.94 9.6 0.2 4.8 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.18 001159796.2_43525001_2 - 0.28 11.4 1.6 1.5 9.1 0.0 3.1 3 0 0 3 3 3 0 PPR repeat TPR_3 PF07720.10 001159796.2_43525001_2 - 0.75 9.7 3.4 2.1 8.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.29 001190204.1_49823001_2 - 6.2e-06 26.1 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.11 001190204.1_49823001_2 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Pam16 Ras PF00071.20 001161859.1_39522001_1 - 4.6e-32 110.7 0.0 5.7e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001161859.1_39522001_1 - 1.7e-09 37.8 0.0 2.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.16 001161859.1_39522001_1 - 0.00011 21.6 0.0 0.00019 20.9 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.19 001161859.1_39522001_1 - 0.00052 19.4 0.0 0.00068 19.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001161859.1_39522001_1 - 0.00072 19.4 0.0 0.38 10.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.27 001161859.1_39522001_1 - 0.0012 19.1 0.0 0.0031 17.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 001161859.1_39522001_1 - 0.0018 18.4 0.2 0.06 13.5 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.4 001161859.1_39522001_1 - 0.0026 18.2 0.0 0.0026 18.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.25 001161859.1_39522001_1 - 0.0026 18.1 0.0 0.014 15.8 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.4 001161859.1_39522001_1 - 0.0051 16.8 0.5 0.027 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.4 001161859.1_39522001_1 - 0.0062 16.1 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.10 001161859.1_39522001_1 - 0.0092 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.21 001161859.1_39522001_1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.12 001161859.1_39522001_1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001161859.1_39522001_1 - 0.023 14.9 2.2 0.17 12.1 2.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.4 001161859.1_39522001_1 - 0.05 13.7 0.1 0.096 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.15 001161859.1_39522001_1 - 0.1 12.3 0.1 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein SRPRB PF09439.8 001161859.1_39522001_1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DNA_ligase_A_M PF01068.19 001244103.1_49828001_1 - 3.4e-61 206.3 0.0 5.4e-61 205.7 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.12 001244103.1_49828001_1 - 2.8e-33 115.6 0.1 7.5e-33 114.2 0.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus LIG3_BRCT PF16759.3 001244103.1_49828001_1 - 3.1e-26 91.3 0.0 6.6e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain zf-PARP PF00645.16 001244103.1_49828001_1 - 2.4e-23 82.6 1.6 7.2e-23 81.1 1.6 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DNA_ligase_A_C PF04679.13 001244103.1_49828001_1 - 1.5e-18 67.1 0.0 3.3e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.3 001244103.1_49828001_1 - 6.7e-07 29.5 0.0 2e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.8 001244103.1_49828001_1 - 0.00027 21.1 0.0 0.00063 19.9 0.0 1.6 1 0 0 1 1 1 1 RNA ligase Synaptonemal_3 PF15191.4 001244103.1_49828001_1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 SelB-wing_2 PF09106.9 001244103.1_49828001_3 - 0.064 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Ion_trans PF00520.29 001131411.1_43529001_2 - 4.1e-49 166.9 7.7 6e-49 166.3 7.7 1.2 1 0 0 1 1 1 1 Ion transport protein K_channel_TID PF07941.9 001131411.1_43529001_2 - 9.1e-39 131.7 18.7 2.7e-38 130.1 18.7 1.9 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain BTB_2 PF02214.20 001131411.1_43529001_2 - 1.5e-27 95.7 0.1 2.9e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.14 001131411.1_43529001_2 - 9.6e-13 47.8 5.4 9.6e-13 47.8 5.4 2.4 2 0 0 2 2 2 1 Ion channel Sigma_reg_N PF13800.4 001131411.1_43529001_2 - 0.64 10.2 2.7 10 6.3 0.0 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal STAT_bind PF02864.13 001133211.1_43529001_1 - 6.8e-79 265.1 0.3 6.8e-79 265.1 0.3 1.8 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.18 001133211.1_43529001_1 - 5e-54 182.8 19.3 5e-54 182.8 19.3 1.7 2 0 0 2 2 2 1 STAT protein, all-alpha domain STAT_int PF02865.15 001133211.1_43529001_1 - 1.9e-39 134.8 8.3 1.9e-39 134.8 8.3 2.9 3 0 0 3 3 3 1 STAT protein, protein interaction domain STAT1_TAZ2bind PF12162.6 001133211.1_43529001_1 - 3.3e-15 55.2 0.2 6.4e-15 54.3 0.2 1.5 1 0 0 1 1 1 1 STAT1 TAZ2 binding domain SH2 PF00017.22 001133211.1_43529001_1 - 3.2e-09 36.6 0.2 1.5e-08 34.5 0.0 2.3 3 0 0 3 3 3 1 SH2 domain TRPM_tetra PF16519.3 001133211.1_43529001_1 - 0.18 11.8 6.4 0.78 9.7 0.3 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Sec20 PF03908.11 001133211.1_43529001_1 - 8.3 6.3 8.1 23 4.8 0.1 2.9 3 0 0 3 3 3 0 Sec20 SNAPc19 PF15497.4 001243678.1_49823001_3 - 8.2e-24 83.7 12.9 1.2e-23 83.2 12.9 1.3 1 0 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Mito_carr PF00153.25 001127273.1_39522001_1 - 3.1e-60 200.0 4.0 4.3e-20 71.3 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_8 PF13855.4 001097444.1_49827001_3 - 7e-73 240.2 93.9 8.3e-13 47.8 3.8 10.8 7 3 4 11 11 11 11 Leucine rich repeat LRR_4 PF12799.5 001097444.1_49827001_3 - 2.2e-29 100.8 97.8 0.00015 21.9 7.6 14.1 8 2 6 14 14 14 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001097444.1_49827001_3 - 1.9e-18 66.5 29.8 4e-05 23.5 1.2 5.9 2 1 1 5 5 5 4 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001097444.1_49827001_3 - 2.2e-11 43.4 32.1 0.0003 20.2 1.6 7.0 1 1 8 9 9 9 6 Leucine-rich repeat TIR PF01582.18 001097444.1_49827001_3 - 2.6e-10 40.2 0.4 4.8e-10 39.4 0.4 1.4 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001097444.1_49827001_3 - 3.1e-06 26.7 86.6 1.5 9.5 0.1 18.3 18 2 0 18 18 18 7 Leucine Rich Repeat TIR_2 PF13676.4 001097444.1_49827001_3 - 0.013 15.7 0.1 0.024 14.8 0.1 1.4 1 0 0 1 1 1 0 TIR domain LRRNT PF01462.16 001097444.1_49827001_3 - 0.018 14.5 0.2 0.018 14.5 0.2 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRRCT PF01463.22 001097444.1_49827001_3 - 0.13 12.8 0.2 0.82 10.2 0.2 2.5 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Apolipoprotein PF01442.16 001159308.1_49824001_3 - 5.6e-55 186.1 20.5 7e-53 179.3 8.7 3.4 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.13 001159308.1_49824001_3 - 0.001 18.6 17.2 0.085 12.3 3.5 2.3 1 1 1 2 2 2 2 Exonuclease VII, large subunit PilJ PF13675.4 001159308.1_49824001_3 - 0.0013 18.7 15.9 0.0075 16.2 4.6 3.3 2 2 1 3 3 3 2 Type IV pili methyl-accepting chemotaxis transducer N-term YtxH PF12732.5 001159308.1_49824001_3 - 0.0077 16.6 2.7 0.37 11.2 0.0 3.5 4 1 0 4 4 2 1 YtxH-like protein Prominin PF05478.9 001159308.1_49824001_3 - 0.011 13.6 3.3 0.018 12.9 0.3 2.0 1 1 1 2 2 2 0 Prominin BcrAD_BadFG PF01869.18 001159308.1_49824001_3 - 0.017 14.5 0.1 0.046 13.1 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF1664 PF07889.10 001159308.1_49824001_3 - 0.075 12.9 7.0 0.32 10.9 1.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.9 001159308.1_49824001_3 - 0.084 12.8 12.8 0.78 9.7 1.0 2.9 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF4795 PF16043.3 001159308.1_49824001_3 - 0.1 12.0 9.2 2.1 7.8 5.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) ZnuA PF01297.15 001159308.1_49824001_3 - 0.11 11.7 1.6 0.26 10.5 1.3 1.6 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF1690 PF07956.9 001159308.1_49824001_3 - 0.23 11.8 11.8 0.19 12.0 0.8 3.4 2 2 2 4 4 4 0 Protein of Unknown function (DUF1690) Baculo_PEP_C PF04513.10 001159308.1_49824001_3 - 0.29 11.1 10.7 8.4 6.3 0.6 4.6 2 1 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF479 PF04336.10 001159308.1_49824001_3 - 0.57 10.5 7.7 0.56 10.5 0.3 3.5 1 1 3 4 4 4 0 Protein of unknown function, DUF479 DUF883 PF05957.11 001159308.1_49824001_3 - 0.71 10.4 14.5 0.51 10.8 0.6 4.3 2 1 4 6 6 5 0 Bacterial protein of unknown function (DUF883) DUF1917 PF08939.8 001159308.1_49824001_3 - 1.4 8.6 4.3 9.6 5.9 4.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) YojJ PF10372.7 001159308.1_49824001_3 - 1.4 8.9 9.2 0.37 10.8 0.3 3.7 3 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus Serine_rich PF08824.8 001159308.1_49824001_3 - 2.7 7.8 10.1 0.12 12.2 1.5 2.4 3 0 0 3 3 3 0 Serine rich protein interaction domain Serpin PF00079.18 001129958.1_49823001_1 - 2.9e-118 395.3 1.1 3.4e-118 395.1 1.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) 7tm_3 PF00003.20 001314264.1_09023001_2 - 6.4e-23 81.6 32.0 1e-22 81.0 31.4 1.5 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF1345 PF07077.9 001314264.1_09023001_2 - 2.4 7.7 14.7 0.038 13.5 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF373 PF04123.11 001314264.1_09023001_2 - 4.5 6.5 11.3 8.8 5.5 11.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MMS19_C PF12460.6 001132163.2_43527001_2 - 3.4e-107 359.0 0.7 3.4e-107 359.0 0.7 2.7 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.4 001132163.2_43527001_2 - 5.7e-86 288.2 8.0 6.3e-85 284.7 0.1 3.7 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II DUF3437 PF11919.6 001132163.2_43527001_2 - 2.1e-06 27.4 1.6 3.6 7.5 0.0 6.0 6 0 0 6 6 6 2 Domain of unknown function (DUF3437) HEAT_2 PF13646.4 001132163.2_43527001_2 - 2.8e-05 24.3 0.4 2.8e-05 24.3 0.4 4.3 5 0 0 5 5 5 1 HEAT repeats RTP1_C1 PF10363.7 001132163.2_43527001_2 - 0.0033 17.4 5.6 6.3 6.9 0.1 5.5 5 1 1 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.20 001132163.2_43527001_2 - 0.033 14.3 0.2 0.033 14.3 0.2 7.1 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.4 001132163.2_43527001_2 - 0.062 13.6 0.4 0.062 13.6 0.4 6.9 6 2 1 8 8 8 0 HEAT-like repeat Serpin PF00079.18 001244132.1_49825001_1 - 2.7e-92 309.8 0.0 3.2e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) TIR PF01582.18 001135927.1_39525001_3 - 2.8e-25 89.0 0.3 5.5e-25 88.0 0.3 1.5 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001135927.1_39525001_3 - 1.5e-23 82.1 36.2 4.8e-10 38.9 3.8 7.5 2 2 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.5 001135927.1_39525001_3 - 3e-17 62.2 43.1 4.6e-06 26.7 0.7 8.3 6 2 3 10 10 10 6 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001135927.1_39525001_3 - 4.3e-12 46.1 0.0 7.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001135927.1_39525001_3 - 8.4e-10 37.8 27.9 0.37 10.8 0.1 11.0 12 0 0 12 12 12 3 Leucine Rich repeat LRR_9 PF14580.4 001135927.1_39525001_3 - 3e-06 26.7 8.6 0.034 13.5 0.1 4.1 3 1 1 4 4 4 3 Leucine-rich repeat LRRCT PF01463.22 001135927.1_39525001_3 - 5.4e-05 23.3 0.1 0.00029 21.0 0.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001135927.1_39525001_3 - 0.0073 16.5 47.3 4.3 8.1 0.2 11.9 11 2 0 11 11 11 3 Leucine Rich Repeat TIR-like PF10137.7 001135927.1_39525001_3 - 0.12 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain bZIP_2 PF07716.13 001139451.1_39522001_1 - 4.8e-16 58.4 11.9 9.5e-16 57.5 11.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.19 001139451.1_39522001_1 - 9.2e-07 28.7 7.2 9.2e-07 28.7 7.2 1.7 2 0 0 2 2 2 1 bZIP transcription factor Cnn_1N PF07989.9 001139451.1_39522001_1 - 0.013 15.4 0.4 0.033 14.2 0.4 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_Maf PF03131.15 001139451.1_39522001_1 - 0.054 13.9 5.3 0.13 12.7 5.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Zip PF02535.20 001163602.1_39523001_1 - 1.6e-79 267.4 26.9 3.1e-79 266.5 6.2 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Resolvase PF00239.19 001163602.1_39523001_2 - 1.1 9.2 5.8 0.14 12.1 1.7 1.6 2 0 0 2 2 2 0 Resolvase, N terminal domain Mito_carr PF00153.25 001142890.1_39523001_1 - 1.6e-63 210.5 0.1 1.6e-20 72.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein bZIP_2 PF07716.13 001139450.1_39522001_1 - 1.2e-17 63.6 12.7 2.6e-17 62.5 12.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.19 001139450.1_39522001_1 - 6.4e-05 22.8 9.0 0.00012 22.0 9.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.15 001139450.1_39522001_1 - 0.0015 18.8 4.1 0.003 17.9 4.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Cnn_1N PF07989.9 001139450.1_39522001_1 - 0.012 15.6 0.7 0.028 14.4 0.7 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 PAF-AH_p_II PF03403.11 001322806.1_49824001_1 - 5.6e-168 558.2 0.0 6.8e-168 557.9 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.5 001322806.1_49824001_1 - 1.4e-08 33.9 0.0 6.6e-08 31.6 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.6 001322806.1_49824001_1 - 1.6e-06 27.4 0.0 0.0023 17.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.18 001322806.1_49824001_1 - 5.2e-06 26.1 0.0 8.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001322806.1_49824001_1 - 9.2e-06 25.1 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.9 001322806.1_49824001_1 - 1.6e-05 23.9 0.0 0.0024 16.8 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.5 001322806.1_49824001_1 - 0.00044 20.8 0.0 0.0021 18.6 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.14 001322806.1_49824001_1 - 0.0058 16.3 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.5 001322806.1_49824001_1 - 0.0095 15.6 0.0 0.025 14.2 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.16 001322806.1_49824001_1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.11 001322806.1_49824001_1 - 0.042 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SH2 PF00017.22 001131793.1_43529001_3 - 5.3e-43 144.8 0.1 1.5e-20 72.9 0.0 2.5 2 0 0 2 2 2 2 SH2 domain RasGAP PF00616.17 001131793.1_43529001_3 - 8.2e-26 90.9 2.7 2.5e-18 66.4 0.5 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.27 001131793.1_43529001_3 - 1.4e-16 60.7 0.1 6.7e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 PH domain C2 PF00168.28 001131793.1_43529001_3 - 7.5e-12 45.3 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.26 001131793.1_43529001_3 - 6.1e-10 38.4 0.0 1.5e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 001131793.1_43529001_3 - 6e-05 22.7 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH2_2 PF14633.4 001131793.1_43529001_3 - 0.00028 20.2 0.0 0.0085 15.4 0.0 2.3 2 0 0 2 2 2 1 SH2 domain SH3_2 PF07653.15 001131793.1_43529001_3 - 0.0028 17.2 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.4 001131793.1_43529001_3 - 0.011 16.0 0.2 0.13 12.6 0.2 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain TFIIE_beta PF02186.13 001244861.1_49823001_1 - 4.1e-24 84.5 0.8 9.1e-24 83.4 0.2 1.9 2 0 0 2 2 2 1 TFIIE beta subunit core domain Lectin_C PF00059.19 001145217.1_49822001_3 - 3e-25 88.9 2.8 1.1e-24 87.1 0.5 2.6 3 0 0 3 3 3 1 Lectin C-type domain AIP3 PF03915.11 001145217.1_49822001_3 - 0.0013 17.7 0.4 0.0018 17.3 0.4 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 UL45 PF05473.10 001145217.1_49822001_3 - 0.0063 16.0 1.0 0.012 15.1 0.2 1.7 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Peptidase_C32 PF05411.10 001145217.1_49822001_3 - 0.034 13.9 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase IncA PF04156.12 001145217.1_49822001_3 - 0.047 13.3 3.9 0.089 12.4 3.9 1.5 1 0 0 1 1 1 0 IncA protein APH PF01636.21 001145217.1_49822001_3 - 0.081 12.7 2.3 0.12 12.1 2.3 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CENP-F_leu_zip PF10473.7 001145217.1_49822001_3 - 0.23 11.4 8.4 0.42 10.5 8.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.4 001145217.1_49822001_3 - 9.5 6.3 12.4 11 6.1 1.2 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 GATA PF00320.25 001252179.1_39523001_1 - 4.3e-29 99.7 19.4 1.6e-14 53.1 5.8 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.10 001252179.1_39523001_1 - 0.00026 20.3 12.6 0.013 14.9 1.5 2.7 3 0 0 3 3 3 2 TFIIB zinc-binding A2L_zn_ribbon PF08792.8 001252179.1_39523001_1 - 0.0054 16.3 2.8 7.1 6.3 0.0 4.1 4 0 0 4 4 4 1 A2L zinc ribbon domain Zn-ribbon_8 PF09723.8 001252179.1_39523001_1 - 0.0075 16.2 3.0 0.82 9.7 0.2 2.8 2 1 0 2 2 2 2 Zinc ribbon domain ArfGap PF01412.16 001252179.1_39523001_1 - 0.047 13.6 8.2 0.15 11.9 1.1 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf DZR PF12773.5 001252179.1_39523001_1 - 0.18 11.7 9.8 33 4.5 2.1 3.0 1 1 1 2 2 2 0 Double zinc ribbon DUF2387 PF09526.8 001252179.1_39523001_1 - 0.22 11.6 6.0 6.4 6.9 0.1 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) eIF-5_eIF-2B PF01873.15 001252179.1_39523001_1 - 0.39 10.5 6.6 4.6 7.0 0.3 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.9 001252179.1_39523001_1 - 0.52 10.1 7.1 2.3 8.1 0.8 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.10 001252179.1_39523001_1 - 1.1 9.4 5.8 3.7 7.7 0.4 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Elf1 PF05129.11 001252179.1_39523001_1 - 1.1 9.2 4.4 16 5.5 0.6 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Prim_Zn_Ribbon PF08273.10 001252179.1_39523001_1 - 5.4 7.3 10.3 1.2 9.4 1.2 2.8 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Pkinase PF00069.23 001136013.1_29625001_1 - 2.2e-76 256.6 0.7 2.6e-76 256.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001136013.1_29625001_1 - 1.7e-38 132.2 0.1 8.8e-38 129.9 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.20 001136013.1_29625001_1 - 0.00097 18.6 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.4 001136013.1_29625001_1 - 0.005 16.1 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Mur_ligase PF01225.23 001136013.1_29625001_1 - 0.024 14.8 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Kdo PF06293.12 001136013.1_29625001_1 - 0.028 13.7 0.1 0.054 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001136013.1_29625001_1 - 0.13 12.1 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.5 001252178.1_39524001_2 - 5e-36 123.0 7.9 2.2e-13 50.4 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001252178.1_39524001_2 - 2.1e-26 91.4 4.7 6.8e-11 42.1 0.2 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.28 001252178.1_39524001_2 - 5e-26 89.8 1.7 5.6e-06 26.4 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.4 001252178.1_39524001_2 - 4.3e-25 87.6 2.1 3.6e-09 36.8 0.1 3.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 001252178.1_39524001_2 - 3.2e-22 76.1 2.1 0.00019 21.5 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat PDZ PF00595.22 001244414.2_49825001_1 - 3e-20 72.2 2.5 7.8e-13 48.5 0.1 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001244414.2_49825001_1 - 1.9e-11 44.0 0.1 1.7e-07 31.3 0.0 2.3 1 1 1 2 2 2 2 PDZ domain TIR_2 PF13676.4 001282345.1_24222001_1 - 2.2e-08 34.2 0.0 3.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001282345.1_24222001_1 - 0.00066 19.4 0.0 0.0018 17.9 0.0 1.7 2 0 0 2 2 2 1 TIR domain Zip PF02535.20 001127272.1_39522001_1 - 2.7e-48 164.8 17.6 8.4e-48 163.2 17.6 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter IF2_N PF04760.13 001127272.1_39522001_1 - 0.067 12.9 0.2 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MBF1 PF08523.8 001193597.1_29622001_3 - 1.3e-25 89.5 6.8 2.5e-25 88.6 6.8 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.20 001193597.1_29622001_3 - 1.2e-12 47.5 0.3 2.2e-12 46.7 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.4 001193597.1_29622001_3 - 3.9e-05 23.8 0.0 6.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.5 001193597.1_29622001_3 - 0.027 14.4 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PLA2_B PF01735.16 001204226.1_29626001_3 - 6.2e-28 97.3 0.0 6.6e-27 93.9 0.0 2.0 2 0 0 2 2 2 1 Lysophospholipase catalytic domain C2 PF00168.28 001204226.1_29626001_3 - 8.2e-18 64.5 0.0 1.9e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Sec3-PIP2_bind PF15277.4 001260925.1_29623001_3 - 7.6e-23 80.3 0.1 1.2e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Synaptobrevin PF00957.19 001260925.1_29623001_3 - 2.3e-06 27.2 0.4 2.3e-06 27.2 0.4 1.7 2 0 0 2 2 2 1 Synaptobrevin Apo-CII PF05355.9 001195136.1_29621001_1 - 1.1e-42 143.9 0.5 1.4e-42 143.5 0.5 1.1 1 0 0 1 1 1 1 Apolipoprotein C-II CD20 PF04103.13 001243394.1_49825001_2 - 3.1e-45 153.9 5.1 5.2e-45 153.2 5.1 1.4 1 0 0 1 1 1 1 CD20-like family SK_channel PF03530.12 001243394.1_49825001_2 - 0.027 14.3 0.2 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 Calcium-activated SK potassium channel 7tm_1 PF00001.19 001009241.1_39523001_3 - 3.9e-50 170.4 21.8 9.2e-50 169.2 21.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001009241.1_39523001_3 - 7.6e-09 35.2 17.7 9.2e-09 34.9 17.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SEP PF08059.11 001244443.1_49823001_3 - 1.8e-27 95.6 0.2 5.6e-27 94.0 0.1 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.18 001244443.1_49823001_3 - 2.3e-19 69.2 0.1 4.7e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.4 001244443.1_49823001_3 - 2.4e-16 59.1 0.5 5.2e-16 58.0 0.5 1.6 1 0 0 1 1 1 1 UBA-like domain Cornifin PF02389.13 001131664.1_43527001_1 - 0.036 14.1 2.8 0.066 13.3 2.8 1.3 1 0 0 1 1 1 0 Cornifin (SPRR) family Alpha-2-MRAP_C PF06401.9 001131664.1_43527001_3 - 1.8e-69 233.8 26.5 6.5e-69 232.0 19.1 2.1 2 0 0 2 2 2 2 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.9 001131664.1_43527001_3 - 7.3e-43 145.2 9.6 4.4e-39 133.0 0.1 3.2 3 0 0 3 3 3 3 Alpha-2-macroglobulin RAP, N-terminal domain Ig_3 PF13927.4 001131518.1_43529001_1 - 2.2e-75 249.1 0.2 1.7e-13 50.8 0.0 6.7 7 0 0 7 7 6 6 Immunoglobulin domain I-set PF07679.14 001131518.1_43529001_1 - 1.8e-66 220.1 0.0 1.2e-14 53.9 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.23 001131518.1_43529001_1 - 4.3e-53 177.3 0.0 1.5e-09 37.8 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.4 001131518.1_43529001_1 - 1.5e-49 166.1 0.0 2.9e-08 33.8 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.19 001131518.1_43529001_1 - 8.3e-46 154.1 6.6 6e-18 64.8 0.1 4.7 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.15 001131518.1_43529001_1 - 1.1e-20 73.7 3.8 0.014 15.4 0.0 9.2 6 4 1 7 7 7 4 Immunoglobulin V-set domain Ig_5 PF16681.3 001131518.1_43529001_1 - 2.8e-10 40.3 0.0 0.031 14.6 0.0 5.6 6 0 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001131518.1_43529001_1 - 1.2e-06 28.9 0.3 0.0018 18.7 0.3 3.0 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.3 001131518.1_43529001_1 - 2.8e-06 27.1 0.0 0.095 12.6 0.0 5.1 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.3 001131518.1_43529001_1 - 9e-06 25.8 0.0 1.6 9.0 0.0 4.7 5 0 0 5 5 4 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.10 001131518.1_43529001_1 - 1.1e-05 25.3 1.3 0.13 12.2 0.0 4.1 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain C2-set PF05790.13 001131518.1_43529001_1 - 0.00022 21.2 0.0 0.73 9.9 0.0 4.1 4 0 0 4 4 4 1 Immunoglobulin C2-set domain BiPBP_C PF06832.10 001131518.1_43529001_1 - 0.0053 16.6 0.0 8.6 6.4 0.0 3.7 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Adeno_E3_CR1 PF02440.13 001131518.1_43529001_1 - 0.013 15.1 0.0 0.93 9.2 0.0 3.7 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 Sp38 PF07354.10 001131518.1_43529001_1 - 0.015 14.0 0.0 0.15 10.8 0.0 2.4 3 0 0 3 3 3 0 Zona-pellucida-binding protein (Sp38) Interfer-bind PF09294.8 001131518.1_43529001_1 - 0.072 13.3 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 1 0 Interferon-alpha/beta receptor, fibronectin type III Erythro-docking PF09277.9 001131518.1_43529001_3 - 0.6 9.9 3.6 20 5.1 0.1 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking SH2 PF00017.22 001315788.1_49822001_1 - 1.4e-11 44.2 0.0 2.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.14 001315788.1_49822001_1 - 2.9e-11 43.4 2.7 7.3e-11 42.1 2.7 1.7 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.5 001131568.1_43524001_1 - 3.7e-22 78.6 0.0 2.2e-12 47.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001131568.1_43524001_1 - 5.7e-21 74.1 0.1 2.6e-07 30.7 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.4 001131568.1_43524001_1 - 1.6e-19 67.8 0.0 9.4e-06 25.5 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.28 001131568.1_43524001_1 - 9.8e-19 66.8 0.0 1.8e-05 24.9 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.4 001131568.1_43524001_1 - 6.6e-18 64.7 0.1 1.6e-08 34.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) TIR PF01582.18 001329084.1_37925001_1 - 8.2e-29 100.5 0.4 1.3e-28 99.9 0.4 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001329084.1_37925001_1 - 2.3e-20 72.0 23.1 8.6e-07 28.5 2.1 6.7 4 3 3 7 7 7 4 Leucine rich repeat TIR_2 PF13676.4 001329084.1_37925001_1 - 3.6e-14 52.8 0.0 7.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001329084.1_37925001_1 - 7.9e-14 51.4 26.8 0.00015 21.9 0.3 7.6 6 1 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001329084.1_37925001_1 - 1.9e-09 37.1 5.2 0.00072 19.0 0.1 3.6 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.4 001329084.1_37925001_1 - 1.3e-07 31.0 14.8 2.2 8.4 0.1 9.1 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.31 001329084.1_37925001_1 - 0.0053 16.9 26.0 0.92 10.1 1.3 9.5 8 3 1 9 9 9 1 Leucine Rich Repeat APA3_viroporin PF11289.6 001329084.1_37925001_1 - 0.0054 16.2 0.2 0.012 15.1 0.2 1.5 1 0 0 1 1 1 1 Coronavirus accessory protein 3a LRRCT PF01463.22 001329084.1_37925001_1 - 0.062 13.7 0.1 0.27 11.7 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain TIR-like PF10137.7 001329084.1_37925001_1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Voltage_CLC PF00654.18 001305027.1_22426001_1 - 1.9e-84 283.8 31.4 1.9e-84 283.8 31.4 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.26 001305027.1_22426001_1 - 0.18 12.2 0.1 0.56 10.6 0.0 1.9 2 0 0 2 2 2 0 CBS domain Pkinase PF00069.23 001112816.1_39524001_2 - 1.3e-72 244.2 0.0 2e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001112816.1_39524001_2 - 3.5e-41 141.1 0.0 8.5e-41 139.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase AdenylateSensor PF16579.3 001112816.1_39524001_2 - 4.1e-14 52.9 0.1 1.7e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.4 001112816.1_39524001_2 - 1.3e-06 27.8 0.0 2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.20 001112816.1_39524001_2 - 0.00095 18.7 0.4 0.003 17.0 0.4 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.12 001112816.1_39524001_2 - 0.0016 17.7 0.1 0.0033 16.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.21 001112816.1_39524001_2 - 0.034 13.9 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.7 001112816.1_39524001_2 - 0.13 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC LRR_8 PF13855.4 001135925.1_39525001_1 - 4.6e-25 87.0 42.0 8.6e-13 47.7 1.7 7.0 3 2 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.5 001135925.1_39525001_1 - 5.6e-21 74.1 38.3 2.8e-06 27.4 0.0 7.7 5 2 4 9 9 9 7 Leucine Rich repeats (2 copies) TIR PF01582.18 001135925.1_39525001_1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001135925.1_39525001_1 - 5.9e-08 32.0 33.9 1.3 9.1 0.9 10.8 11 0 0 11 11 11 4 Leucine Rich repeat TIR_2 PF13676.4 001135925.1_39525001_1 - 6e-07 29.6 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001135925.1_39525001_1 - 1.9e-06 27.4 11.5 0.06 12.7 1.4 3.5 2 1 1 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.31 001135925.1_39525001_1 - 0.00017 21.4 36.6 9.7 7.0 0.0 11.3 9 3 1 10 10 10 2 Leucine Rich Repeat LRRCT PF01463.22 001135925.1_39525001_1 - 0.013 15.8 0.1 0.15 12.5 0.0 2.7 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain DUF1863 PF08937.9 001135925.1_39525001_1 - 0.035 14.3 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) CAS_CSE1 PF03378.13 001243215.1_49827001_2 - 1e-178 594.3 5.2 1.6e-178 593.7 2.8 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.8 001243215.1_49827001_2 - 5.7e-167 555.0 6.0 1.3e-166 553.9 6.0 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.17 001243215.1_49827001_2 - 2e-10 40.3 0.4 1.2e-09 37.8 0.1 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.10 001243215.1_49827001_2 - 0.014 15.4 0.0 0.014 15.4 0.0 3.8 4 1 0 5 5 5 0 Exportin 1-like protein RRM_1 PF00076.20 001195568.1_43528001_2 - 2.1e-31 107.4 0.1 6.6e-16 57.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.9 001195568.1_43528001_2 - 2.4e-05 24.2 0.1 0.0029 17.5 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.4 001195568.1_43528001_2 - 0.017 14.6 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001195568.1_43528001_2 - 0.056 13.2 0.0 5.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.4 001195568.1_43528001_2 - 0.061 13.2 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif IL8 PF00048.18 001256776.2_49822001_1 - 1.5e-16 60.2 0.2 1.5e-16 60.2 0.2 1.6 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like Abhydrolase_1 PF00561.18 001266346.2_29626001_2 - 3.8e-38 131.5 0.7 4.6e-38 131.2 0.7 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.14 001266346.2_29626001_2 - 2.2e-24 84.7 0.0 3.6e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.6 001266346.2_29626001_2 - 0.00011 21.4 0.0 0.00045 19.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.10 001266346.2_29626001_2 - 0.039 13.3 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.5 001266346.2_29626001_2 - 0.053 14.0 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LSM PF01423.20 001243426.1_49822001_1 - 4.2e-15 55.1 0.2 6.2e-15 54.5 0.2 1.3 1 0 0 1 1 1 1 LSM domain Ank_2 PF12796.5 001315599.1_49825001_1 - 1.2e-26 93.0 6.0 3e-12 46.8 0.1 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001315599.1_49825001_1 - 3.2e-21 75.3 4.1 4.7e-05 23.7 0.0 5.7 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.28 001315599.1_49825001_1 - 6.2e-21 73.7 4.7 0.0046 17.2 0.0 6.7 5 1 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.4 001315599.1_49825001_1 - 2.1e-19 67.4 2.8 0.047 14.1 0.1 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.4 001315599.1_49825001_1 - 7e-12 45.2 8.0 0.00098 19.3 0.1 6.0 5 2 2 7 7 7 4 Ankyrin repeats (many copies) V-ATPase_C PF03223.13 001190205.1_49824001_2 - 4e-165 549.6 7.6 4.6e-165 549.4 7.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF4300 PF14133.4 001190205.1_49824001_2 - 0.043 13.4 0.3 0.043 13.4 0.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4300) ASXH PF13919.4 001190205.1_49824001_2 - 0.073 13.0 0.6 0.15 11.9 0.6 1.6 1 0 0 1 1 1 0 Asx homology domain TRAF_BIRC3_bd PF16673.3 001132279.1_43529001_1 - 7.2e-14 51.2 1.3 1.3e-13 50.4 1.3 1.3 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain Jiv90 PF14901.4 001185066.1_49828001_3 - 9e-37 125.1 0.4 1.9e-36 124.0 0.4 1.6 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone DnaJ PF00226.29 001185066.1_49828001_3 - 1.1e-19 70.2 0.1 2.4e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain fn3 PF00041.19 001131694.1_43526001_2 - 0.0037 17.4 0.0 0.0071 16.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain PDZ PF00595.22 001244863.1_49823001_1 - 8.4e-18 64.4 3.8 1.2e-09 38.2 0.0 2.9 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001244863.1_49823001_1 - 7.7e-09 35.6 0.4 3.7e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain MHC_I PF00129.16 001123403.1_39523001_2 - 3.5e-43 147.1 0.0 4.7e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001123403.1_39523001_2 - 1e-09 38.6 0.0 6.5e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin C1-set domain MHC_I_3 PF16497.3 001123403.1_39523001_2 - 0.0001 21.7 0.1 0.00016 21.1 0.1 1.4 1 1 0 1 1 1 1 MHC-I family domain Ig_2 PF13895.4 001123403.1_39523001_2 - 0.00034 20.8 0.0 0.57 10.4 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.4 001123403.1_39523001_2 - 0.0061 17.0 0.1 0.047 14.2 0.0 2.5 3 0 0 3 3 3 1 Immunoglobulin domain PRA1 PF03208.17 001161869.1_39522001_1 - 3.7e-37 127.0 2.1 4.4e-37 126.7 2.1 1.0 1 0 0 1 1 1 1 PRA1 family protein 7tm_1 PF00001.19 001172875.1_09923001_1 - 1.6e-52 178.3 21.5 3.4e-52 177.2 21.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CSD PF00313.20 001243420.1_49822001_1 - 4.8e-13 48.6 0.1 6.6e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.9 001243420.1_49822001_1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain Pkinase PF00069.23 001244878.1_49827001_2 - 4.2e-70 236.0 0.0 8.6e-70 235.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001244878.1_49827001_2 - 4.8e-27 94.7 0.0 6.8e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.17 001244878.1_49827001_2 - 2.7e-17 63.0 1.2 5.9e-17 61.9 1.2 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.27 001244878.1_49827001_2 - 4.4e-11 43.1 0.1 7.2e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.4 001244878.1_49827001_2 - 0.0027 16.9 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ATG16 PF08614.9 001244878.1_49827001_2 - 0.16 12.0 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) LRRNT PF01462.16 001141985.1_49822001_1 - 3.8e-06 26.3 9.5 4.3e-06 26.1 1.6 3.4 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRRCT PF01463.22 001141985.1_49822001_1 - 5.4e-05 23.3 0.6 0.00019 21.6 0.6 2.0 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LST1 PF05083.11 001141985.1_49822001_1 - 0.12 12.6 1.1 0.21 11.8 1.1 1.4 1 0 0 1 1 1 0 LST-1 protein 7tm_1 PF00001.19 001135970.1_22423001_1 - 3.9e-51 173.7 25.4 9.9e-51 172.4 25.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001135970.1_22423001_1 - 4.5e-08 32.7 21.1 5.6e-08 32.4 21.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Neur_chan_LBD PF02931.21 001131305.1_43529001_3 - 2.3e-48 164.4 0.0 3.3e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001131305.1_43529001_3 - 1.6e-46 159.2 1.3 2.9e-45 155.0 1.3 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region OAD_gamma PF04277.11 001131305.1_43529001_3 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SDF PF00375.16 001244425.2_49825001_3 - 9.1e-134 446.2 29.9 1.1e-133 445.9 29.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MT PF12777.5 001244425.2_49825001_3 - 0.015 14.2 0.1 0.025 13.5 0.1 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor DUF2207 PF09972.7 001244425.2_49825001_3 - 0.036 12.7 5.2 0.12 11.0 0.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.14 001284787.1_29524001_2 - 3.6e-45 154.3 33.5 7.6e-44 149.9 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 001284787.1_29524001_2 - 0.00019 20.3 19.7 0.2 10.3 3.5 4.2 4 0 0 4 4 4 4 Sugar (and other) transporter PTR2 PF00854.19 001284787.1_29524001_2 - 4.4 5.9 9.5 0.057 12.1 0.4 2.2 3 0 0 3 3 3 0 POT family Sds3 PF08598.9 001243408.1_49826001_3 - 1.2e-18 67.9 10.6 1.9e-18 67.2 10.6 1.3 1 0 0 1 1 1 1 Sds3-like Exonuc_VII_L PF02601.13 001243408.1_49826001_3 - 2.3 7.5 8.2 3.4 7.0 8.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_1 PF00170.19 001315740.1_49823001_3 - 2.2e-08 33.9 22.2 3.5e-08 33.3 22.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001315740.1_49823001_3 - 6.2e-06 26.1 22.2 1e-05 25.4 22.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001315740.1_49823001_3 - 1.8e-05 25.0 15.8 3e-05 24.3 15.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.10 001315740.1_49823001_3 - 0.00088 19.5 2.9 0.00088 19.5 2.9 1.8 2 0 0 2 2 1 1 Cell division protein ZapB DUF5082 PF16888.3 001315740.1_49823001_3 - 0.032 14.4 2.8 0.054 13.7 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) APG6 PF04111.10 001315740.1_49823001_3 - 0.11 11.7 10.1 0.16 11.2 10.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.12 001315740.1_49823001_3 - 0.22 11.4 4.1 0.33 10.8 4.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.6 001315740.1_49823001_3 - 0.23 10.6 3.5 0.34 10.0 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.12 001315740.1_49823001_3 - 0.28 10.8 8.7 0.43 10.2 8.7 1.2 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.13 001315740.1_49823001_3 - 0.39 10.4 10.6 0.65 9.7 10.6 1.2 1 0 0 1 1 1 0 Mnd1 family Spc24 PF08286.9 001315740.1_49823001_3 - 0.8 9.8 3.7 1.4 9.0 3.7 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4527 PF15030.4 001315740.1_49823001_3 - 0.91 8.8 11.8 1.7 8.0 11.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) HAUS6_N PF14661.4 001315740.1_49823001_3 - 1 8.8 6.1 1.5 8.3 6.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF342 PF03961.11 001315740.1_49823001_3 - 1.4 7.3 6.3 2 6.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.4 001315740.1_49823001_3 - 1.7 7.8 4.4 2.5 7.2 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Asp-B-Hydro_N PF05279.9 001315740.1_49823001_3 - 2 8.3 7.9 3 7.7 7.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FAM76 PF16046.3 001315740.1_49823001_3 - 4.3 6.5 9.0 6.8 5.8 9.0 1.2 1 0 0 1 1 1 0 FAM76 protein DivIC PF04977.13 001315740.1_49823001_3 - 9.4 6.0 11.0 5.8 6.6 9.1 1.5 1 1 0 1 1 1 0 Septum formation initiator Atg14 PF10186.7 001315740.1_49823001_3 - 9.7 5.0 9.5 16 4.3 9.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-3CxxC PF13695.4 001104930.1_39524001_3 - 9.1e-30 102.9 0.5 1.7e-29 102.0 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.2 001104930.1_39524001_3 - 0.00035 21.1 0.9 0.00035 21.1 0.9 3.2 2 1 0 2 2 2 1 Zinc-binding domain Exo_endo_phos PF03372.21 001139471.1_49823001_1 - 7.7e-13 48.6 0.0 1.8e-12 47.4 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.4 001139471.1_49823001_1 - 0.011 15.5 0.0 0.086 12.6 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Pkinase PF00069.23 001159795.1_43525001_1 - 1.6e-70 237.4 0.0 2.5e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001159795.1_43525001_1 - 4.4e-45 153.9 0.0 7.3e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.26 001159795.1_43525001_1 - 2e-23 82.4 0.0 4.8e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.4 001159795.1_43525001_1 - 9e-07 28.3 0.1 0.0011 18.2 0.0 2.7 2 1 1 3 3 3 2 Kinase-like Spt5_N PF11942.6 001159795.1_43525001_1 - 0.0035 18.2 2.0 0.0084 16.9 2.0 1.5 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal APH PF01636.21 001159795.1_43525001_1 - 0.011 15.5 0.0 0.078 12.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.10 001159795.1_43525001_1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Ribosomal_60s PF00428.17 001159795.1_43525001_1 - 2.1 8.8 9.4 0.056 13.9 2.4 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_C14 PF00656.20 001161640.1_49825001_1 - 4.2e-47 161.1 0.0 9.8e-47 159.8 0.0 1.6 2 0 0 2 2 2 1 Caspase domain DED PF01335.19 001161640.1_49825001_1 - 9.7e-41 137.8 15.6 3.8e-21 75.0 3.8 2.6 2 0 0 2 2 2 2 Death effector domain OAD_gamma PF04277.11 001161640.1_49825001_1 - 0.016 15.6 1.6 0.077 13.5 0.1 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain 7tm_1 PF00001.19 001145040.1_29623001_1 - 1.7e-52 178.2 9.1 5.7e-52 176.4 9.1 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ctr PF04145.13 001145040.1_29623001_1 - 0.00024 21.6 0.2 0.00093 19.7 0.2 2.0 2 0 0 2 2 2 1 Ctr copper transporter family 7TM_GPCR_Srsx PF10320.7 001145040.1_29623001_1 - 0.0071 15.6 3.5 0.0097 15.2 3.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CBP_BcsG PF11658.6 001145040.1_29623001_1 - 0.095 10.9 0.4 0.13 10.5 0.4 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG AA_permease_2 PF13520.4 001252182.1_39523001_1 - 2.5e-47 161.6 33.2 1.4e-33 116.3 18.8 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.19 001252182.1_39523001_1 - 3.3e-24 85.2 33.0 3.6e-23 81.8 33.0 2.4 1 1 0 1 1 1 1 Amino acid permease Granin PF01271.15 001319389.1_29525001_1 - 3.3e-114 382.8 70.4 3.1e-90 303.6 64.9 2.0 1 1 1 2 2 2 2 Granin (chromogranin or secretogranin) DLH PF01738.16 001319607.1_29525001_3 - 8.2e-05 22.1 0.0 0.00031 20.2 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.6 001319607.1_29525001_3 - 0.00055 19.1 0.1 0.4 9.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.5 001319607.1_29525001_3 - 0.0083 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.11 001319607.1_29525001_3 - 0.019 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_C12 PF01088.19 001134085.1_43524001_1 - 2.5e-71 239.6 0.0 4.1e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Nsp1_C PF05064.11 001260617.1_29625001_2 - 1.2e-37 128.2 6.5 2.4e-37 127.2 6.5 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF4164 PF13747.4 001260617.1_29625001_2 - 0.099 12.8 6.2 0.032 14.4 1.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) GAS PF13851.4 001260617.1_29625001_2 - 1.4 8.2 13.7 3.3 6.9 13.6 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prp18 PF02840.13 001260617.1_29625001_2 - 2.1 8.3 5.7 3.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Prp18 domain DUF1664 PF07889.10 001260617.1_29625001_2 - 4.7 7.1 8.7 2.5 8.0 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF342 PF03961.11 001260617.1_29625001_2 - 6.2 5.2 5.7 10 4.5 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-CW PF07496.13 001314327.1_09025001_2 - 0.0059 16.5 0.1 4.8 7.2 0.0 2.8 1 1 1 2 2 2 2 CW-type Zinc Finger bZIP_Maf PF03131.15 001314327.1_09025001_3 - 4.4e-16 59.0 3.6 4.4e-16 59.0 3.6 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.19 001314327.1_09025001_3 - 2.4e-08 33.8 9.8 2.4e-08 33.8 9.8 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.13 001314327.1_09025001_3 - 2e-05 24.4 7.1 2e-05 24.4 7.1 2.4 2 0 0 2 2 2 1 Basic region leucine zipper T3SS_basalb_I PF17001.3 001314327.1_09025001_3 - 0.094 13.2 0.3 0.094 13.2 0.3 2.4 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI FAM165 PF14981.4 001265695.1_29621001_2 - 3.6e-29 100.2 5.4 5e-29 99.7 5.4 1.2 1 0 0 1 1 1 1 FAM165 family HSL_N PF06350.10 001128154.1_39525001_1 - 3.2e-115 384.2 0.0 4e-115 383.9 0.0 1.1 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.11 001128154.1_39525001_1 - 2.6e-35 122.1 0.5 1.2e-33 116.6 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.7 001128154.1_39525001_1 - 3.2e-06 26.1 0.0 5.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase SNAP PF14938.4 001131455.1_43528001_1 - 1.4e-108 362.5 22.6 1.7e-108 362.2 22.6 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.4 001131455.1_43528001_1 - 6.2e-07 29.5 9.7 0.0047 17.1 0.3 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.4 001131455.1_43528001_1 - 0.0042 16.9 3.0 0.48 10.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Spatacsin_C PF14649.4 001131455.1_43528001_1 - 0.056 12.5 10.2 0.76 8.7 2.5 2.3 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_2 PF07719.15 001131455.1_43528001_1 - 0.17 11.9 11.1 11 6.3 1.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.4 001131455.1_43528001_1 - 0.52 10.9 7.4 16 6.2 0.5 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.26 001131455.1_43528001_1 - 3.5 7.5 9.9 17 5.3 0.8 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RHIM PF12721.5 001279589.1_24225001_1 - 1.3e-13 51.1 7.2 1.3e-13 51.1 7.2 3.7 3 1 0 3 3 3 1 RIP homotypic interaction motif TIR_2 PF13676.4 001279589.1_24225001_1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 TIR domain Nup153 PF08604.8 001302105.1_40429001_1 - 7e-235 780.5 39.3 7e-235 780.5 39.3 4.3 3 1 1 4 4 4 1 Nucleoporin Nup153-like zf-RanBP PF00641.16 001302105.1_40429001_1 - 9.6e-44 146.2 39.6 5.4e-12 44.7 1.2 4.6 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Nup_retrotrp_bd PF10599.7 001302105.1_40429001_1 - 1.6e-24 86.2 20.4 1.6e-24 86.2 20.4 12.6 5 2 3 8 8 8 1 Retro-transposon transporting motif HTH_IclR PF09339.8 001302105.1_40429001_1 - 0.15 11.7 0.1 0.33 10.6 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Vps36-NZF-N PF16988.3 001302105.1_40429001_1 - 1.2 8.5 21.8 6.5 6.1 0.2 5.4 5 0 0 5 5 5 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Aldedh PF00171.20 001315593.1_49823001_1 - 1.2e-79 267.8 0.0 1.6e-79 267.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.12 001315593.1_49823001_1 - 0.0092 14.9 0.0 0.017 14.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Rogdi_lz PF10259.7 001315593.1_49823001_1 - 0.024 14.0 0.2 0.042 13.2 0.2 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein RuvB_N PF05496.10 001315593.1_49823001_1 - 0.064 12.4 0.0 7.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Abhydrolase_1 PF00561.18 001319528.1_29525001_3 - 3.9e-16 59.3 0.1 5.4e-14 52.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.5 001319528.1_29525001_3 - 3.7e-09 37.4 0.1 6e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.10 001319528.1_29525001_3 - 1.8e-05 23.8 0.0 2.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.6 001319528.1_29525001_3 - 0.00024 20.3 0.0 0.003 16.7 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Ssl1 PF04056.12 001244311.1_49823001_1 - 5.9e-95 316.4 0.1 8.1e-95 316.0 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.4 001244311.1_49823001_1 - 1.2e-12 48.3 0.0 2.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.10 001244311.1_49823001_1 - 2.4e-10 40.4 29.5 1.9e-09 37.5 22.8 3.1 2 1 0 2 2 2 1 TFIIH C1-like domain VWA PF00092.26 001244311.1_49823001_1 - 1.3e-06 28.7 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.4 001244311.1_49823001_1 - 0.02 14.7 0.0 0.053 13.3 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain DZR PF12773.5 001244311.1_49823001_1 - 0.14 12.1 18.9 3.8 7.5 0.9 3.2 2 1 1 3 3 3 0 Double zinc ribbon IBR PF01485.19 001244311.1_49823001_1 - 0.32 11.1 19.5 0.11 12.7 11.0 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.4 001244311.1_49823001_1 - 5.9 7.1 21.5 27 5.0 16.0 3.4 3 0 0 3 3 3 0 Ring finger domain PAC1 PF16094.3 001244457.1_49823001_1 - 1.2e-132 441.2 2.9 1.5e-132 440.9 2.9 1.0 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Clathrin PF00637.18 001132789.1_43527001_2 - 3.5e-18 65.7 9.2 7.4e-14 51.7 3.9 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.6 001132789.1_43527001_2 - 7.9e-18 64.2 0.5 2.1e-17 62.9 0.5 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.4 001132789.1_43527001_2 - 1.1e-06 28.2 4.2 2.3e-06 27.2 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.5 001132789.1_43527001_2 - 2.2e-05 24.5 3.6 5.4e-05 23.3 3.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.4 001132789.1_43527001_2 - 3.2e-05 24.0 4.8 7.4e-05 22.8 4.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.4 001132789.1_43527001_2 - 0.017 15.0 4.1 0.041 13.7 4.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3H2C3 PF17122.3 001132789.1_43527001_2 - 0.027 14.4 6.1 0.067 13.1 6.1 1.7 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4 PF00097.23 001132789.1_43527001_2 - 0.029 14.1 4.2 0.064 13.0 4.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.4 001132789.1_43527001_2 - 0.05 13.2 1.5 0.86 9.2 0.0 3.5 4 0 0 4 4 4 0 TPR repeat zf-RING_UBOX PF13445.4 001132789.1_43527001_2 - 0.06 13.2 5.2 0.17 11.8 5.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.9 001132789.1_43527001_2 - 0.088 13.0 4.4 0.25 11.5 4.4 1.8 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.5 001132789.1_43527001_2 - 0.098 12.6 0.9 0.27 11.2 0.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1086 PF06461.9 001132789.1_43527001_2 - 0.15 11.8 0.8 15 5.3 0.3 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) zf-C3HC4_4 PF15227.4 001132789.1_43527001_2 - 1.6 8.8 4.1 3.9 7.6 4.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Lig_chan PF00060.24 001185013.2_29629001_3 - 1.9e-59 199.7 0.1 3.3e-59 198.9 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.26 001185013.2_29629001_3 - 4.9e-59 200.1 0.1 7.7e-59 199.4 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.7 001185013.2_29629001_3 - 2.6e-45 153.2 0.2 5.9e-45 152.0 0.1 1.7 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001185013.2_29629001_3 - 1e-23 83.8 0.0 1.7e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF1325 PF07039.9 001257445.1_29623001_3 - 2.9e-40 137.3 0.1 5.5e-40 136.4 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Filament PF00038.19 001257445.1_29623001_3 - 0.0071 15.8 3.7 0.01 15.3 3.7 1.1 1 0 0 1 1 1 1 Intermediate filament protein TUDOR PF00567.22 001257445.1_29623001_3 - 0.024 14.5 0.3 0.74 9.7 0.0 2.7 2 1 1 3 3 3 0 Tudor domain Moulting_cycle PF04870.14 001257445.1_29623001_3 - 0.11 11.7 1.4 0.15 11.2 1.4 1.1 1 0 0 1 1 1 0 Moulting cycle Bcl-2 PF00452.17 001315668.1_49823001_3 - 4.8e-05 23.7 0.0 9.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family CF222 PF15661.3 001315668.1_49823001_3 - 0.00016 20.6 0.0 0.00034 19.5 0.0 1.5 1 0 0 1 1 1 1 C6orf222, uncharacterised family RBB1NT PF08169.9 001315668.1_49823001_3 - 0.018 15.2 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Peptidase_C1 PF00112.21 001314266.1_09023001_2 - 5.6e-86 288.0 4.1 8.2e-86 287.5 4.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001314266.1_09023001_2 - 2.9e-10 40.3 1.6 5.1e-10 39.5 1.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 001314266.1_09023001_2 - 8.4e-05 21.4 3.7 0.049 12.3 1.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Cation_efflux PF01545.19 001136211.1_49823001_1 - 1.5e-44 152.0 8.9 1.8e-44 151.7 8.9 1.1 1 0 0 1 1 1 1 Cation efflux family CUB PF00431.18 001315806.1_49826001_2 - 1.6e-47 160.3 1.3 1.2e-25 89.8 0.0 2.7 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.16 001315806.1_49826001_2 - 2.4e-36 123.5 77.1 3.4e-11 43.0 14.9 5.6 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A V-set PF07686.15 001305917.1_29722001_2 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set_2 PF15910.3 001305917.1_29722001_2 - 6.8e-05 22.8 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 ICOS V-set domain Ig_3 PF13927.4 001305917.1_29722001_2 - 0.03 14.8 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.14 001305917.1_29722001_2 - 0.13 12.2 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain IL8 PF00048.18 001305906.1_29721001_1 - 8.7e-26 89.7 2.9 1.3e-25 89.2 2.9 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like V-set PF07686.15 001244730.1_49824001_3 - 7e-35 119.3 0.0 1.5e-16 60.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.23 001244730.1_49824001_3 - 4.2e-13 49.1 0.0 1.8e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001244730.1_49824001_3 - 4.2e-12 46.4 0.0 0.00018 21.9 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001244730.1_49824001_3 - 1.4e-11 44.2 0.0 0.00014 21.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set_CD47 PF08204.9 001244730.1_49824001_3 - 5.5e-05 23.0 0.0 0.0095 15.8 0.0 2.6 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Ig_2 PF13895.4 001244730.1_49824001_3 - 0.00012 22.2 0.0 0.26 11.5 0.0 3.2 3 1 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.3 001244730.1_49824001_3 - 0.00042 20.2 0.0 0.34 10.8 0.0 2.8 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Pox_C7_F8A PF03287.12 001244730.1_49824001_3 - 0.0046 16.8 0.1 0.097 12.5 0.0 2.3 2 0 0 2 2 2 1 Poxvirus C7/F8A protein Cu2_monoox_C PF03712.13 001244730.1_49824001_3 - 0.042 13.2 0.0 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain VCBS PF13517.4 001168818.1_40424001_1 - 0.0036 17.7 0.4 2 8.9 0.0 2.8 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.4 001168818.1_40424001_1 - 0.0081 15.6 0.0 0.074 12.5 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain FG-GAP PF01839.21 001168818.1_40424001_1 - 0.015 15.3 2.1 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 FG-GAP repeat Pkinase_Tyr PF07714.15 001315613.1_49828001_2 - 4.1e-86 288.4 0.0 5.9e-86 287.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.22 001315613.1_49828001_2 - 7.4e-53 177.3 0.0 2.5e-30 104.7 0.0 2.3 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.4 001315613.1_49828001_2 - 6.8e-43 145.5 77.4 2.5e-40 137.2 28.0 3.7 2 1 1 3 3 3 2 Growth factor receptor domain IV Pkinase PF00069.23 001315613.1_49828001_2 - 1.1e-36 126.5 0.0 1.6e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.18 001315613.1_49828001_2 - 6.7e-26 90.8 86.1 1.5e-24 86.4 39.1 4.0 2 1 1 3 3 3 1 Furin-like cysteine rich region APH PF01636.21 001315613.1_49828001_2 - 0.0018 18.1 1.7 0.037 13.8 0.2 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family HSP70 PF00012.18 001328289.1_39726001_2 - 1.3e-258 859.0 7.7 1.5e-258 858.8 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001328289.1_39726001_2 - 2.2e-16 59.5 0.4 5.6e-15 54.8 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.4 001328289.1_39726001_2 - 0.00034 20.9 0.7 2.1 8.7 0.0 3.5 3 0 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.14 001328289.1_39726001_2 - 0.0013 18.4 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.18 001328289.1_39726001_2 - 0.005 16.2 0.2 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family PTR2 PF00854.19 001315736.1_49824001_2 - 2.1e-117 392.2 2.2 2.6e-117 391.9 2.2 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.14 001315736.1_49824001_2 - 2e-13 49.9 22.6 2e-13 49.9 22.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.5 001315736.1_49824001_2 - 0.016 14.0 9.7 0.019 13.7 2.4 3.6 3 1 1 4 4 4 0 MFS_1 like family Prenyltransf PF01255.17 001244123.1_49823001_3 - 1.6e-78 263.1 0.0 2.4e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Ten1_2 PF15490.4 001244123.1_49823001_3 - 0.038 13.6 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit DUF480 PF04337.10 001244123.1_49823001_3 - 0.07 13.1 2.5 0.13 12.3 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF480 E1-E2_ATPase PF00122.18 001204393.1_49827001_2 - 1.3e-64 217.5 1.5 1.3e-64 217.5 1.5 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.19 001204393.1_49827001_2 - 4e-44 150.4 0.6 8.3e-44 149.3 0.6 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.24 001204393.1_49827001_2 - 1.4e-20 72.5 0.1 8.8e-20 70.0 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.4 001204393.1_49827001_2 - 4.8e-20 71.3 0.6 9.4e-20 70.4 0.6 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.24 001204393.1_49827001_2 - 1.6e-18 67.7 0.2 9.8e-18 65.1 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.10 001204393.1_49827001_2 - 6e-06 26.0 0.6 1.2e-05 25.1 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.5 001204393.1_49827001_2 - 0.05 13.9 0.1 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase C2 PF00168.28 001265809.1_29624001_1 - 5.8e-55 183.8 0.3 2.7e-28 98.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.4 001265809.1_29624001_1 - 6.4e-05 22.4 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 2 CEP76 C2 domain TMEM52 PF14979.4 001265809.1_29624001_1 - 0.00013 21.8 2.6 0.0003 20.6 2.6 1.6 1 0 0 1 1 1 1 Transmembrane 52 DOCK-C2 PF14429.4 001265809.1_29624001_1 - 0.00025 20.8 0.0 0.63 9.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins MAP17 PF15807.3 001265809.1_29624001_1 - 0.00041 20.4 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Trypan_PARP PF05887.9 001265809.1_29624001_1 - 0.011 15.7 0.2 0.023 14.6 0.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAM176 PF14851.4 001265809.1_29624001_1 - 0.017 14.7 0.2 0.031 13.8 0.2 1.4 1 0 0 1 1 1 0 FAM176 family EphA2_TM PF14575.4 001265809.1_29624001_1 - 0.018 15.7 0.3 0.056 14.1 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.3 001265809.1_29624001_1 - 0.034 14.8 0.0 0.85 10.3 0.0 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal LYRIC PF15686.3 001265809.1_29624001_1 - 0.14 11.5 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family Comm PF15957.3 001265809.1_29624001_1 - 0.38 11.0 4.1 0.48 10.7 0.0 2.9 3 0 0 3 3 3 0 Commissureless SPRY PF00622.26 001243568.1_49826001_1 - 6.6e-13 48.7 0.2 1.3e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 SPRY domain PHD20L1_u1 PF16660.3 001243568.1_49826001_1 - 0.51 11.0 2.6 1.5 9.5 2.6 1.7 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 DED PF01335.19 001285642.1_09023001_1 - 1.6e-34 117.9 14.0 2.6e-24 85.1 3.0 2.7 3 0 0 3 3 3 2 Death effector domain Peptidase_C14 PF00656.20 001285642.1_09023001_1 - 1.5e-23 83.9 0.0 2.5e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain GRIM-19 PF06212.10 001244646.1_49822001_3 - 3.1e-52 175.9 0.1 3.8e-52 175.6 0.1 1.1 1 0 0 1 1 1 1 GRIM-19 protein COX14 PF14880.4 001244646.1_49822001_3 - 0.071 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly G-alpha PF00503.18 001123117.1_49823001_1 - 6e-124 413.6 2.1 6.9e-124 413.4 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001123117.1_49823001_1 - 1.9e-17 63.1 2.1 8.3e-13 48.0 0.1 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001123117.1_49823001_1 - 2.9e-05 23.4 2.6 0.0047 16.2 0.7 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.11 001123117.1_49823001_1 - 0.00016 21.8 0.4 0.51 10.4 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.9 001123117.1_49823001_1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.4 001123117.1_49823001_1 - 0.095 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.4 001123117.1_49823001_1 - 0.097 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.16 001123117.1_49823001_1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Cation_efflux PF01545.19 001163598.1_39523001_1 - 5.7e-44 150.1 9.7 6.8e-44 149.8 9.7 1.1 1 0 0 1 1 1 1 Cation efflux family TFIID-31kDa PF02291.13 001285790.1_40423001_2 - 8e-51 171.1 0.0 1.2e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AAA_18 PF13238.4 001285790.1_40423001_2 - 2.1e-07 31.4 0.3 4.5e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 AAA domain CENP-S PF15630.4 001285790.1_40423001_2 - 2.4e-06 27.7 0.1 4.8e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein AAA_17 PF13207.4 001285790.1_40423001_2 - 2.5e-05 24.6 0.1 2.5e-05 24.6 0.1 1.8 2 0 0 2 2 1 1 AAA domain Bromo_TP PF07524.11 001285790.1_40423001_2 - 9.5e-05 22.2 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.27 001285790.1_40423001_2 - 0.00012 22.4 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.4 001285790.1_40423001_2 - 0.0002 21.5 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Histone PF00125.22 001285790.1_40423001_2 - 0.00029 21.1 0.3 0.00057 20.2 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.4 001285790.1_40423001_2 - 0.0035 17.3 0.1 0.0064 16.5 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_16 PF13191.4 001285790.1_40423001_2 - 0.0061 16.8 0.3 0.012 15.9 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.4 001285790.1_40423001_2 - 0.01 15.8 0.6 0.042 13.9 0.6 2.0 1 1 0 1 1 1 0 AAA domain SKI PF01202.20 001285790.1_40423001_2 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.13 001285790.1_40423001_2 - 0.016 15.0 0.2 0.027 14.2 0.2 1.3 1 0 0 1 1 1 0 NTPase ADK PF00406.20 001285790.1_40423001_2 - 0.019 14.9 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Adenylate kinase AAA_22 PF13401.4 001285790.1_40423001_2 - 0.02 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.12 001285790.1_40423001_2 - 0.039 13.8 0.2 0.09 12.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.16 001285790.1_40423001_2 - 0.059 13.0 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase RuvB_N PF05496.10 001285790.1_40423001_2 - 0.072 12.2 0.2 0.12 11.5 0.2 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.4 001285790.1_40423001_2 - 0.086 12.4 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.15 001285790.1_40423001_2 - 0.089 12.7 0.4 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.11 001285790.1_40423001_2 - 0.098 11.9 0.7 0.34 10.1 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_32 PF13654.4 001285790.1_40423001_2 - 0.1 11.2 0.3 0.82 8.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.21 001285790.1_40423001_2 - 0.14 12.3 0.1 0.36 11.0 0.1 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TLV_coat PF00429.17 001308066.1_08024001_1 - 7.4e-30 104.0 0.1 7.4e-30 104.0 0.1 2.5 1 1 0 2 2 2 1 ENV polyprotein (coat polyprotein) Hydrolase_4 PF12146.6 001267030.1_29623001_3 - 2e-13 50.1 0.0 9e-07 28.3 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.18 001267030.1_29623001_3 - 4.4e-08 32.9 0.4 0.0021 17.6 0.5 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.19 001267030.1_29623001_3 - 7e-06 25.5 0.0 0.0002 20.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.11 001267030.1_29623001_3 - 0.0025 17.4 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.16 001267030.1_29623001_3 - 0.0033 16.9 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.10 001267030.1_29623001_3 - 0.01 15.6 0.0 0.079 12.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.5 001267030.1_29623001_3 - 0.025 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.14 001267030.1_29623001_3 - 0.034 13.8 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF818 PF05677.10 001267030.1_29623001_3 - 0.06 12.2 0.1 0.087 11.6 0.1 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Asp2 PF16929.3 001267030.1_29623001_3 - 0.068 12.1 0.0 0.094 11.6 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter zf-H2C2_2 PF13465.4 001302761.1_40422001_1 - 8.9e-14 51.1 25.0 6.5e-10 38.9 0.3 4.9 4 1 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.24 001302761.1_40422001_1 - 1.7e-13 50.1 30.6 0.00029 21.0 0.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001302761.1_40422001_1 - 7.9e-10 38.6 29.1 0.0033 18.0 1.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger FYVE PF01363.19 001302761.1_40422001_1 - 0.00038 20.4 19.0 0.0079 16.2 3.6 2.6 1 1 1 2 2 2 2 FYVE zinc finger zf-C2H2_jaz PF12171.6 001302761.1_40422001_1 - 0.034 14.3 9.2 4.9 7.5 1.5 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001302761.1_40422001_1 - 0.041 13.5 0.8 0.041 13.5 0.8 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.5 001302761.1_40422001_1 - 0.077 13.3 0.4 0.077 13.3 0.4 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.4 001302761.1_40422001_1 - 0.089 12.4 1.1 0.089 12.4 1.1 4.9 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.3 001302761.1_40422001_1 - 0.53 10.9 7.2 3.1 8.5 4.2 2.5 1 1 2 3 3 3 0 zinc-ribbon family zf-C2HE PF16278.3 001302761.1_40422001_1 - 0.55 10.6 6.8 12 6.3 0.1 3.4 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.5 001302761.1_40422001_1 - 1.1 9.5 14.0 5.7 7.2 3.5 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) NinF PF05810.10 001302761.1_40422001_1 - 6.1 6.7 6.3 38 4.1 0.0 3.1 3 0 0 3 3 3 0 NinF protein Zn-ribbon_8 PF09723.8 001302761.1_40422001_1 - 7.9 6.6 19.5 0.8 9.7 0.3 4.7 3 1 2 5 5 5 0 Zinc ribbon domain 7tm_1 PF00001.19 001204430.1_29624001_3 - 4.3e-28 98.2 1.1 7.1e-28 97.4 1.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001204430.1_29624001_3 - 0.064 12.5 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv E1-E2_ATPase PF00122.18 001204430.1_29624001_3 - 0.48 9.6 1.7 20 4.3 0.4 2.2 2 0 0 2 2 2 0 E1-E2 ATPase WD40 PF00400.30 001281479.1_39523001_1 - 1.5e-49 164.8 25.3 7.6e-09 35.9 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001281479.1_39523001_1 - 1.5e-10 41.1 0.8 0.0034 17.5 0.0 4.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001281479.1_39523001_1 - 4e-05 23.4 0.2 0.0054 16.5 0.0 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001281479.1_39523001_1 - 8.6e-05 21.5 0.1 0.73 8.6 0.0 4.0 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.14 001281479.1_39523001_1 - 0.006 15.0 0.0 0.025 13.0 0.1 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.3 001281479.1_39523001_1 - 0.0082 15.4 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.6 001281479.1_39523001_1 - 0.011 14.2 10.8 0.14 10.6 0.1 4.5 3 2 2 5 5 5 0 Nucleoporin Nup120/160 PD40 PF07676.10 001281479.1_39523001_1 - 0.38 10.6 3.7 17 5.4 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF4431 PF14485.4 001281479.1_39523001_3 - 0.41 10.4 2.4 8.2 6.2 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) Nsp1_C PF05064.11 001132371.2_43527001_1 - 2.2e-37 127.3 6.5 4.3e-37 126.3 6.5 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF4164 PF13747.4 001132371.2_43527001_1 - 0.13 12.4 5.5 0.045 13.9 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) NUDIX_4 PF14815.4 001283675.1_29524001_1 - 4.9e-25 87.5 0.7 1.3e-24 86.1 0.7 1.7 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.23 001283675.1_29524001_1 - 3.7e-21 75.5 0.0 9.8e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.21 001283675.1_29524001_1 - 1.4e-08 34.1 0.0 3.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.7 001283675.1_29524001_1 - 0.00018 21.6 4.2 0.0005 20.2 4.2 1.9 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III fn3 PF00041.19 001243884.1_49826001_2 - 2.1e-09 37.4 0.8 0.016 15.4 0.0 4.1 4 0 0 4 4 4 3 Fibronectin type III domain Acetyltransf_1 PF00583.23 001132635.1_43523001_1 - 9.9e-18 64.3 0.0 1.6e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.5 001132635.1_43523001_1 - 4e-14 52.7 0.0 6.6e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.5 001132635.1_43523001_1 - 1.5e-13 50.6 0.0 2.3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.5 001132635.1_43523001_1 - 5.1e-08 32.9 0.0 3.7e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.4 001132635.1_43523001_1 - 8.1e-08 32.2 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.5 001132635.1_43523001_1 - 2.4e-06 28.1 0.0 3.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.5 001132635.1_43523001_1 - 5.8e-06 26.5 0.0 9.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.8 001132635.1_43523001_1 - 4.6e-05 23.2 0.0 8.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.4 001132635.1_43523001_1 - 0.043 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.3 001132635.1_43523001_1 - 0.05 12.9 0.0 0.66 9.3 0.0 2.1 1 1 0 1 1 1 0 Putative acetyl-transferase VCBS PF13517.4 001266354.1_29626001_1 - 0.016 15.7 0.2 4 8.0 0.0 2.7 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.4 001266354.1_29626001_1 - 0.035 13.6 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 PQQ-like domain FG-GAP PF01839.21 001266354.1_29626001_1 - 0.053 13.5 2.1 5.4 7.1 0.0 2.6 2 0 0 2 2 2 0 FG-GAP repeat LRAT PF04970.11 001244514.1_49823001_3 - 7.8e-39 132.8 0.0 1.1e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Calici_PP_N PF08405.9 001244514.1_49823001_3 - 0.011 14.5 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal Myb_DNA-bind_4 PF13837.4 001319530.1_29525001_1 - 2e-11 44.0 0.4 7.4e-11 42.2 0.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.7 001319530.1_29525001_1 - 0.014 15.5 0.1 0.036 14.2 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Piwi PF02171.15 001315802.1_49826001_1 - 5.2e-91 304.9 0.0 7.4e-91 304.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.20 001315802.1_49826001_1 - 3.5e-33 114.2 0.1 6.5e-33 113.3 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.3 001315802.1_49826001_1 - 2.4e-05 24.9 0.0 5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.8 001315802.1_49826001_1 - 0.0038 16.7 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain BACK PF07707.13 001319454.1_29525001_2 - 1.2e-25 89.5 4.1 1.8e-25 88.9 2.5 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.29 001319454.1_29525001_2 - 5.7e-23 81.1 0.0 1.5e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.4 001319454.1_29525001_2 - 1.3e-20 72.8 1.3 8.1e-05 22.6 0.0 5.0 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.23 001319454.1_29525001_2 - 2.7e-17 61.9 9.2 7.2e-05 22.2 0.0 5.8 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.4 001319454.1_29525001_2 - 2.3e-09 37.0 0.2 0.14 12.1 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.13 001319454.1_29525001_2 - 1e-08 34.6 5.1 0.0022 17.8 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.4 001319454.1_29525001_2 - 3.5e-07 30.2 0.0 0.024 14.8 0.0 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain DUF3342 PF11822.6 001319454.1_29525001_2 - 0.041 14.0 0.0 0.41 10.7 0.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3342) Kelch_5 PF13854.4 001319454.1_29525001_2 - 0.17 11.8 0.9 14 5.7 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Prenyltransf PF01255.17 001194492.2_29629001_3 - 5.8e-08 32.4 0.0 2.1e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Arm PF00514.21 001319394.1_29527001_1 - 6.4e-42 140.2 19.4 1.2e-07 31.4 0.1 11.9 13 0 0 13 13 13 7 Armadillo/beta-catenin-like repeat Cnd1 PF12717.5 001319394.1_29527001_1 - 6.1e-09 35.9 1.6 0.0046 16.8 0.3 4.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.4 001319394.1_29527001_1 - 2.2e-06 27.9 6.5 1.4 9.3 0.0 6.2 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.20 001319394.1_29527001_1 - 4.4e-06 26.3 1.5 21 5.6 0.0 5.8 5 0 0 5 5 5 0 HEAT repeat Adaptin_N PF01602.18 001319394.1_29527001_1 - 6.5e-06 24.9 2.9 0.0012 17.4 1.1 3.1 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.4 001319394.1_29527001_1 - 1.9e-05 24.8 8.0 0.04 14.2 0.4 4.9 4 1 1 5 5 5 1 HEAT repeats KAP PF05804.10 001319394.1_29527001_1 - 0.00038 18.6 1.2 0.055 11.5 0.0 3.1 1 1 1 3 3 3 1 Kinesin-associated protein (KAP) DUF3361 PF11841.6 001319394.1_29527001_1 - 0.0026 17.6 1.9 2.4 8.0 0.0 4.4 2 1 1 4 4 4 1 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.7 001319394.1_29527001_1 - 0.0033 17.4 0.9 0.04 13.8 0.1 3.1 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Queuosine_synth PF02547.13 001319394.1_29527001_1 - 0.024 13.6 0.4 0.047 12.7 0.1 1.5 2 0 0 2 2 2 0 Queuosine biosynthesis protein Arm_2 PF04826.11 001319394.1_29527001_1 - 0.03 13.6 3.6 0.84 8.9 0.0 3.4 2 1 1 3 3 3 0 Armadillo-like RasGEF_N_2 PF14663.4 001319394.1_29527001_1 - 0.067 13.4 9.3 6.8 7.0 0.0 4.9 5 1 0 5 5 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain UDG PF03167.17 001131099.1_43525001_1 - 5.1e-20 71.9 0.0 2.4e-19 69.7 0.0 1.9 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily AAA_2 PF07724.12 001133667.1_43529001_3 - 1e-44 152.5 0.2 1.7e-44 151.8 0.2 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.5 001133667.1_43529001_3 - 2.2e-19 69.7 0.9 7.5e-09 35.9 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001133667.1_43529001_3 - 2.1e-15 56.3 2.3 0.00017 21.8 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.4 001133667.1_43529001_3 - 2e-14 53.3 2.5 1.9e-06 27.9 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.4 001133667.1_43529001_3 - 5.4e-13 47.7 0.4 0.0007 19.7 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.4 001133667.1_43529001_3 - 3.3e-09 37.0 0.2 0.0002 21.7 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) ClpB_D2-small PF10431.7 001133667.1_43529001_3 - 4.7e-09 36.0 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.12 001133667.1_43529001_3 - 3.4e-08 33.4 0.0 7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.27 001133667.1_43529001_3 - 2.3e-07 31.1 0.1 8.1e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.24 001133667.1_43529001_3 - 6.5e-05 22.6 0.3 0.00016 21.3 0.1 1.7 1 1 1 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.10 001133667.1_43529001_3 - 0.00012 21.4 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Torsin PF06309.9 001133667.1_43529001_3 - 0.026 14.5 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.4 001133667.1_43529001_3 - 0.045 14.0 0.1 0.37 11.0 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.4 001133667.1_43529001_3 - 0.095 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.4 001133667.1_43529001_3 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.4 001133667.1_43529001_3 - 0.13 12.3 1.7 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain YchF-GTPase_C PF06071.11 001133667.1_43529001_3 - 0.14 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Mito_carr PF00153.25 001127279.1_39522001_1 - 1.2e-68 226.9 3.7 7.4e-25 86.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.20 001131886.1_43526001_2 - 6.4e-19 67.4 0.0 1.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001131886.1_43526001_2 - 0.00012 21.8 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif IZUMO PF15005.4 001318079.1_39522001_1 - 1.1e-44 152.3 1.4 1.3e-44 152.1 1.4 1.1 1 0 0 1 1 1 1 Izumo sperm-egg fusion, Ig domain-associated UPF0506 PF11703.6 001318079.1_39522001_1 - 0.089 13.0 2.0 0.21 11.9 2.0 1.5 1 0 0 1 1 1 0 UPF0506 ECSIT PF06239.9 001319410.1_29524001_1 - 2.7e-103 343.8 0.0 3.7e-103 343.3 0.0 1.2 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C PF14784.4 001319410.1_29524001_1 - 1.7e-45 154.4 0.0 2.5e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein ANF_receptor PF01094.26 001185014.2_29629001_3 - 4.8e-59 200.1 0.1 7.7e-59 199.4 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001185014.2_29629001_3 - 1.2e-58 197.1 0.1 2.1e-58 196.2 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001185014.2_29629001_3 - 2.6e-45 153.2 0.2 5.9e-45 152.0 0.1 1.7 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001185014.2_29629001_3 - 6.5e-24 84.5 0.0 1.1e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 zf-C2HC_2 PF13913.4 110315.1_26226120_3 - 0.013 15.3 5.5 0.031 14.1 5.5 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Mito_carr PF00153.25 001127277.1_39522001_1 - 8.4e-73 240.3 0.1 3.7e-24 84.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Lipocalin PF00061.21 001031789.1_49822001_2 - 3.8e-18 65.9 0.6 4.9e-18 65.6 0.6 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001031789.1_49822001_2 - 0.00014 21.7 0.2 0.00017 21.4 0.2 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Gal-bind_lectin PF00337.20 001266363.1_29622001_1 - 1.8e-36 124.5 0.1 2.2e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin tRNA-synt_2d PF01409.18 001319418.1_29525001_1 - 1.8e-90 302.6 0.0 2.4e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) MarR_2 PF12802.5 001319418.1_29525001_1 - 9.7e-05 22.1 0.7 0.00036 20.2 0.7 1.9 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.10 001319418.1_29525001_1 - 0.00027 20.7 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 HTH domain tRNA-synt_2 PF00152.18 001319418.1_29525001_1 - 0.0014 17.7 0.3 0.0049 15.9 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF1204 PF06721.9 001319418.1_29525001_1 - 0.036 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) NAD_binding_6 PF08030.10 001291670.1_32325001_1 - 6.6e-31 107.4 0.0 1.2e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.10 001291670.1_32325001_1 - 9e-23 80.3 0.0 1.7e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.17 001291670.1_32325001_1 - 7e-20 71.3 10.9 1.8e-19 70.0 10.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.30 001291670.1_32325001_1 - 3e-17 60.7 2.8 3.2e-05 23.0 0.0 5.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.4 001291670.1_32325001_1 - 2.2e-13 48.8 8.7 3.6e-05 23.2 0.1 5.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.4 001291670.1_32325001_1 - 5.6e-11 41.3 6.4 0.00079 18.7 0.0 5.0 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.4 001291670.1_32325001_1 - 1.2e-10 41.6 3.0 1.7e-05 25.1 0.1 3.5 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.4 001291670.1_32325001_1 - 4.6e-06 26.2 0.6 0.031 13.9 0.0 3.2 2 2 0 2 2 2 2 EF-hand domain pair NAD_binding_1 PF00175.19 001291670.1_32325001_1 - 3.3e-05 24.3 0.0 0.0039 17.7 0.0 3.2 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.22 001291670.1_32325001_1 - 0.004 17.3 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Basic PF01586.14 001174109.1_39522001_1 - 1.8e-25 89.8 0.0 3.7e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Myogenic Basic domain HLH PF00010.24 001174109.1_39522001_1 - 1.4e-12 47.2 5.4 2.7e-12 46.3 5.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3080 PF11279.6 001174109.1_39522001_1 - 0.0041 16.2 0.2 0.0054 15.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) MWFE PF15879.3 001318974.1_39521001_3 - 1.4e-17 63.5 0.2 1.9e-17 63.0 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit 7tm_1 PF00001.19 001108646.1_45726001_1 - 5e-18 65.1 3.8 6.8e-18 64.7 3.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.7 001108646.1_45726001_1 - 0.00073 18.8 5.2 0.0011 18.3 5.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.7 001108646.1_45726001_1 - 0.014 14.7 0.2 0.025 13.8 0.2 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.4 001108646.1_45726001_1 - 0.057 13.0 0.4 0.085 12.4 0.4 1.1 1 0 0 1 1 1 0 Olfactory receptor Srg PF02118.19 001108646.1_45726001_1 - 3.8 6.9 10.0 1.4 8.4 5.4 2.1 1 1 1 2 2 2 0 Srg family chemoreceptor VWA PF00092.26 001132609.1_43526001_3 - 2.7e-36 125.3 0.4 3.7e-36 124.9 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Trypsin PF00089.24 001132609.1_43526001_3 - 4.7e-30 104.9 0.0 2.5e-29 102.5 0.0 1.9 1 1 0 1 1 1 1 Trypsin Sushi PF00084.18 001132609.1_43526001_3 - 1.3e-19 70.4 9.5 2.9e-08 34.1 0.4 3.5 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) VWA_2 PF13519.4 001132609.1_43526001_3 - 1.1e-10 42.0 0.2 1.9e-10 41.2 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1986 PF09342.9 001132609.1_43526001_3 - 0.00014 22.0 0.0 0.00042 20.5 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) HRM PF02793.20 001132609.1_43526001_3 - 0.00083 19.5 9.3 0.1 12.8 0.3 3.6 3 0 0 3 3 3 2 Hormone receptor domain Trypsin_2 PF13365.4 001132609.1_43526001_3 - 0.0029 18.3 0.0 0.0097 16.7 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain CBM_14 PF01607.22 001132609.1_43526001_3 - 0.41 10.7 5.2 41 4.3 0.3 3.6 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain CLP1_P PF16575.3 001328282.1_39725001_1 - 1.5e-76 256.2 0.0 2.3e-76 255.7 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.3 001328282.1_39725001_1 - 9.7e-34 115.3 0.2 1.8e-33 114.5 0.2 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.12 001328282.1_39725001_1 - 1.5e-30 105.9 0.0 2.4e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.15 001328282.1_39725001_1 - 0.013 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.21 001328282.1_39725001_1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.4 001328282.1_39725001_1 - 0.071 13.5 0.0 0.52 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TniB PF05621.9 001328282.1_39725001_1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.4 001328282.1_39725001_1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Trypsin PF00089.24 001305932.1_29722001_3 - 7.2e-61 205.7 0.1 8.5e-61 205.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001305932.1_29722001_3 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001305932.1_29722001_3 - 0.00037 21.3 0.0 0.0007 20.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Basic PF01586.14 001177749.1_37922001_3 - 4.2e-26 91.8 0.0 1.1e-25 90.5 0.0 1.7 2 0 0 2 2 2 1 Myogenic Basic domain HLH PF00010.24 001177749.1_37922001_3 - 1.5e-12 47.1 5.4 2.8e-12 46.3 5.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3080 PF11279.6 001177749.1_37922001_3 - 0.0035 16.5 0.1 0.0049 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) Enolase_C PF00113.20 001314158.1_09023001_1 - 9.4e-155 514.1 0.0 1.2e-154 513.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.14 001314158.1_09023001_1 - 4.9e-60 201.3 0.0 8.5e-60 200.5 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.4 001314158.1_09023001_1 - 1.1e-08 34.9 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.9 001314158.1_09023001_1 - 4.4e-05 22.6 0.5 8.7e-05 21.7 0.5 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Pkinase_Tyr PF07714.15 001329070.1_37926001_1 - 2.5e-102 341.5 0.0 3.5e-102 341.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001329070.1_37926001_1 - 3.9e-43 147.6 0.0 1.4e-30 106.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.4 001329070.1_37926001_1 - 9.9e-28 96.4 7.1 1.2e-07 32.0 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.14 001329070.1_37926001_1 - 5.1e-17 61.6 7.8 1.4e-08 34.6 0.1 5.2 4 2 1 5 5 5 3 Immunoglobulin I-set domain ig PF00047.23 001329070.1_37926001_1 - 1e-12 47.9 10.4 1e-11 44.7 0.5 4.2 4 2 0 4 4 4 1 Immunoglobulin domain Ig_2 PF13895.4 001329070.1_37926001_1 - 6.6e-09 35.9 3.6 0.075 13.3 0.1 4.5 4 1 0 4 4 4 3 Immunoglobulin domain C1-set PF07654.13 001329070.1_37926001_1 - 0.00097 19.4 0.6 0.04 14.3 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin C1-set domain V-set PF07686.15 001329070.1_37926001_1 - 0.0031 17.5 6.0 0.81 9.7 0.1 5.2 4 3 0 4 4 4 1 Immunoglobulin V-set domain C2-set_2 PF08205.10 001329070.1_37926001_1 - 0.0072 16.2 1.4 0.98 9.4 0.1 3.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.3 001329070.1_37926001_1 - 0.024 14.9 0.0 5.8 7.2 0.0 3.2 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain APH PF01636.21 001329070.1_37926001_1 - 0.04 13.7 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DNA_ligase_A_M PF01068.19 001318075.1_39526001_1 - 5.8e-55 186.0 1.1 1.1e-54 185.0 0.3 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.12 001318075.1_39526001_1 - 1.1e-39 136.4 0.3 2.2e-39 135.5 0.3 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.13 001318075.1_39526001_1 - 2.8e-18 66.2 0.0 1.1e-17 64.3 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_IV PF11411.6 001318075.1_39526001_1 - 3.1e-16 59.0 1.0 6.5e-16 58.0 1.0 1.6 1 0 0 1 1 1 1 DNA ligase IV BRCT PF00533.24 001318075.1_39526001_1 - 2.4e-15 56.6 0.0 1.7e-09 37.8 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.3 001318075.1_39526001_1 - 1.4e-11 44.5 0.1 4.5e-08 33.2 0.0 2.8 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.8 001318075.1_39526001_1 - 7.8e-11 42.4 0.2 1.7e-10 41.3 0.2 1.6 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.17 001318075.1_39526001_1 - 0.0031 17.2 0.8 0.055 13.2 0.8 2.4 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain Proteasome PF00227.24 001319563.1_29522001_1 - 3.4e-44 150.5 0.1 3.9e-44 150.3 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit LAT PF15234.4 001319563.1_29522001_3 - 0.1 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells Mito_carr PF00153.25 001265864.1_29624001_1 - 1.3e-70 233.2 0.1 3.9e-23 81.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Trypsin PF00089.24 001305934.1_29722001_2 - 9.1e-65 218.4 0.1 1.1e-64 218.2 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001305934.1_29722001_2 - 6.4e-08 33.5 0.0 1e-07 32.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain adh_short PF00106.23 001319446.1_29523001_2 - 1e-37 129.4 0.0 1.4e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001319446.1_29523001_2 - 4.6e-26 91.7 0.0 6.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001319446.1_29523001_2 - 1.2e-08 34.9 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.19 001319446.1_29523001_2 - 0.0071 15.7 0.0 0.025 13.9 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.8 001319446.1_29523001_2 - 0.03 13.5 0.0 0.089 12.0 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.6 001319446.1_29523001_2 - 0.087 12.5 0.4 0.33 10.6 0.0 2.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1510 PF07423.9 001131576.1_43529001_1 - 5.6e-05 22.5 9.0 7.8e-05 22.1 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4834 PF16118.3 001131576.1_43529001_1 - 0.027 15.3 9.0 0.043 14.6 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.17 001131576.1_43529001_1 - 0.1 12.2 14.5 0.14 11.7 14.5 1.1 1 0 0 1 1 1 0 Connexin PcfK PF14058.4 001131576.1_43529001_1 - 0.11 12.6 23.4 0.17 12.1 23.4 1.2 1 0 0 1 1 1 0 PcfK-like protein FAM176 PF14851.4 001131576.1_43529001_1 - 0.2 11.2 1.8 0.31 10.6 1.8 1.2 1 0 0 1 1 1 0 FAM176 family CLN3 PF02487.15 001131576.1_43529001_1 - 0.75 8.6 3.3 0.99 8.2 3.3 1.1 1 0 0 1 1 1 0 CLN3 protein OATP PF03137.18 001131576.1_43529001_1 - 1.4 7.0 12.4 2.4 6.2 12.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.16 001131576.1_43529001_1 - 1.8 7.1 7.5 2.9 6.4 7.5 1.3 1 0 0 1 1 1 0 Reduced folate carrier V_ATPase_I PF01496.17 001131576.1_43529001_1 - 2 6.1 10.6 2.6 5.7 10.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF106 PF01956.14 001131576.1_43529001_1 - 2.2 7.9 11.6 2.8 7.5 11.6 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 G0-G1_switch_2 PF15103.4 001131576.1_43529001_1 - 2.4 8.5 12.2 3.9 7.8 12.2 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 EOS1 PF12326.6 001131576.1_43529001_1 - 6.3 6.6 5.8 9.9 5.9 5.8 1.2 1 0 0 1 1 1 0 N-glycosylation protein MAP17 PF15807.3 001131576.1_43529001_1 - 8.7 6.4 15.2 14 5.8 15.2 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Rxt3 PF08642.8 001131576.1_43529001_1 - 9.6 6.9 7.2 16 6.1 7.2 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 EF-hand_4 PF12763.5 001131576.1_43529001_2 - 2.4e-18 65.9 0.1 7.4e-18 64.3 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.3 001131576.1_43529001_2 - 5e-18 64.6 3.8 9.1e-18 63.7 3.8 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.21 001131576.1_43529001_2 - 1.3e-12 48.0 4.3 1.4e-11 44.6 0.0 2.7 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.21 001131576.1_43529001_2 - 1.6e-08 34.5 0.0 4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_pol_Rpc4 PF05132.12 001131576.1_43529001_2 - 0.00016 22.0 1.6 0.0003 21.1 1.6 1.4 1 0 0 1 1 1 1 RNA polymerase III RPC4 EF-hand_1 PF00036.30 001131576.1_43529001_2 - 0.0019 17.5 0.1 0.0054 16.1 0.1 1.8 1 0 0 1 1 1 1 EF hand AAA_23 PF13476.4 001131576.1_43529001_2 - 0.094 13.1 21.1 4.5 7.6 16.8 2.9 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.4 001131576.1_43529001_2 - 0.17 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain EOS1 PF12326.6 001131576.1_43529001_2 - 1 9.1 3.0 1.6 8.5 3.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein NACHT PF05729.10 001114113.1_29627001_2 - 7.3e-34 116.9 0.7 3e-33 114.9 0.0 2.5 3 0 0 3 3 3 1 NACHT domain PYRIN PF02758.14 001114113.1_29627001_2 - 1.8e-26 92.0 3.9 6.3e-26 90.3 3.9 2.0 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain LRR_6 PF13516.4 001114113.1_29627001_2 - 1.3e-10 40.3 22.6 0.00048 19.8 0.1 7.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.5 001114113.1_29627001_2 - 0.022 15.0 9.1 9.4 6.7 0.0 5.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) AAA_22 PF13401.4 001114113.1_29627001_2 - 0.023 14.8 0.0 0.12 12.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.27 001114113.1_29627001_2 - 0.064 13.5 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.4 001114113.1_29627001_2 - 0.066 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.4 001114113.1_29627001_2 - 0.12 12.7 0.1 0.36 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Fz PF01392.20 001163053.1_39522001_1 - 1.7e-28 99.4 2.7 1.7e-28 99.4 2.7 1.7 2 0 0 2 2 2 1 Fz domain NTR PF01759.19 001163053.1_39522001_1 - 3.2e-14 52.5 1.1 5.2e-14 51.8 1.1 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module PurA PF04845.11 001009447.1_39523001_3 - 2.7e-105 350.4 0.0 3.6e-105 350.0 0.0 1.2 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein SUIM_assoc PF16619.3 001009447.1_39523001_3 - 3.1 7.8 10.1 8 6.5 10.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ras PF00071.20 001126361.1_39522001_1 - 1.4e-51 174.2 0.0 1.6e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001126361.1_39522001_1 - 8.7e-19 67.8 0.0 2e-18 66.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001126361.1_39522001_1 - 2.2e-09 36.9 0.0 2.6e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001126361.1_39522001_1 - 0.0049 16.3 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001126361.1_39522001_1 - 0.073 12.8 0.0 4.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Crystall PF00030.17 001173079.1_09922001_1 - 5e-61 202.8 1.4 5.1e-32 109.8 0.2 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001173079.1_09922001_1 - 1.1e-05 25.1 0.0 0.085 12.7 0.0 2.7 2 1 1 3 3 3 2 Peptidase inhibitor family I36 Crystall_3 PF08964.8 001173079.1_09922001_1 - 0.0018 18.3 0.7 0.0088 16.1 0.3 2.2 3 0 0 3 3 3 1 Beta/Gamma crystallin AIMP2_LysRS_bd PF16780.3 001162567.1_39522001_1 - 3.1e-23 81.1 1.2 3.1e-23 81.1 1.2 1.8 2 0 0 2 2 2 1 AIMP2 lysyl-tRNA synthetase binding domain GST_C PF00043.23 001162567.1_39522001_1 - 6.1e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001162567.1_39522001_1 - 8.9e-06 25.7 0.0 6e-05 23.0 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001162567.1_39522001_1 - 2.1e-05 24.2 0.1 5.9e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001162567.1_39522001_1 - 0.00062 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.23 001129740.1_39523001_1 - 1.2e-68 231.2 0.0 1.4e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001129740.1_39523001_1 - 3.7e-24 85.3 0.0 5e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001129740.1_39523001_1 - 4.2e-05 22.9 0.0 0.00036 19.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.21 001129740.1_39523001_1 - 0.0052 16.6 0.1 0.015 15.1 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.12 001129740.1_39523001_1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.14 001129740.1_39523001_1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Thioredoxin PF00085.18 001171315.1_37924001_1 - 2.9e-68 226.2 0.1 1.6e-33 114.6 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.4 001171315.1_37924001_1 - 4.6e-36 124.4 1.1 3.1e-28 98.9 3.1 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.4 001171315.1_37924001_1 - 5.3e-09 36.4 1.7 0.0006 20.1 0.1 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001171315.1_37924001_1 - 5e-08 33.0 0.0 0.0026 17.9 0.0 4.0 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.4 001171315.1_37924001_1 - 2.7e-06 27.4 0.0 0.021 14.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.19 001171315.1_37924001_1 - 0.0001 22.1 0.0 0.16 11.8 0.0 2.8 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_4 PF13462.4 001171315.1_37924001_1 - 0.00036 20.6 0.1 0.9 9.5 0.0 3.8 3 1 0 4 4 4 1 Thioredoxin OST3_OST6 PF04756.11 001171315.1_37924001_1 - 0.00039 19.7 0.0 0.55 9.4 0.0 2.6 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.4 001171315.1_37924001_1 - 0.02 14.8 0.1 0.65 10.0 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin domain Ephrin PF00812.15 001114285.1_49823001_1 - 8.8e-43 145.5 0.0 2e-42 144.3 0.0 1.5 2 0 0 2 2 2 1 Ephrin Ion_trans PF00520.29 001173031.1_09927001_1 - 3.7e-32 111.4 18.6 6.3e-32 110.6 18.6 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.9 001173031.1_09927001_1 - 2.6e-26 91.5 1.2 2.6e-26 91.5 1.2 2.4 3 0 0 3 3 3 1 Transient receptor ion channel II PKD_channel PF08016.10 001173031.1_09927001_1 - 7.2e-13 47.9 16.2 2.2e-12 46.3 16.2 1.7 1 1 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.5 001173031.1_09927001_1 - 2.2e-09 37.6 0.2 1.7e-06 28.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001173031.1_09927001_1 - 2.8e-06 27.4 0.6 0.14 12.4 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.4 001173031.1_09927001_1 - 1.6e-05 25.2 0.4 0.0052 17.2 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.4 001173031.1_09927001_1 - 0.00015 21.8 3.8 2.3 8.9 0.1 5.0 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.28 001173031.1_09927001_1 - 0.00091 19.5 1.1 2.4 8.6 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat PBC PF03792.11 001173031.1_09927001_1 - 0.04 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 PBC domain Crystall PF00030.17 001078659.1_39522001_3 - 4.6e-59 196.4 0.1 4.9e-29 100.2 0.1 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001078659.1_39522001_3 - 0.00054 19.7 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase inhibitor family I36 IRF-3 PF10401.7 001097428.1_49824001_2 - 9.5e-50 168.8 0.0 1.2e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.15 001097428.1_49824001_2 - 2.1e-37 127.4 0.0 9.9e-37 125.3 0.0 1.9 2 0 0 2 2 2 1 Interferon regulatory factor transcription factor Tecti-min-caps PF09300.8 001097428.1_49824001_2 - 0.038 13.9 0.3 0.079 12.9 0.3 1.5 1 0 0 1 1 1 0 Tectiviridae, minor capsid Thyroglobulin_1 PF00086.16 001129733.1_39522001_2 - 3.3e-19 68.2 2.5 8.9e-19 66.8 2.5 1.8 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001129733.1_39522001_2 - 5.3e-11 42.9 22.4 5.3e-11 42.9 22.4 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein DUF1669 PF07894.10 001171497.1_37925001_1 - 5.6e-105 350.7 0.0 7.1e-105 350.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.4 001171497.1_37925001_1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain AF-4 PF05110.11 001171499.1_37927001_1 - 0 1361.1 145.4 0 1361.0 145.4 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Peptidase_S64 PF08192.9 001171499.1_37927001_1 - 0.0011 17.5 20.1 0.0011 17.5 20.1 4.4 3 1 1 4 4 4 1 Peptidase family S64 PglL_A PF15864.3 001171499.1_37927001_2 - 0.018 14.6 0.8 0.018 14.6 0.8 2.9 3 0 0 3 3 3 0 Protein glycosylation ligase zf-C3HC4 PF00097.23 001160087.1_49825001_2 - 3.5e-09 36.3 4.9 1.4e-08 34.3 4.9 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001160087.1_49825001_2 - 2e-08 34.2 4.8 2e-08 34.2 4.8 3.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.4 001160087.1_49825001_2 - 2.7e-08 33.5 3.5 9.1e-08 31.9 3.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.4 001160087.1_49825001_2 - 3.4e-08 33.0 6.2 1.5e-07 31.0 6.2 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.4 001160087.1_49825001_2 - 1.4e-07 31.4 6.2 1.4e-07 31.4 6.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.4 001160087.1_49825001_2 - 2.6e-07 30.3 6.4 2.6e-07 30.3 6.4 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001160087.1_49825001_2 - 4.9e-05 23.0 7.9 4.9e-05 23.0 7.9 3.2 3 2 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 001160087.1_49825001_2 - 0.00024 20.9 5.1 0.00024 20.9 5.1 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-B_box PF00643.22 001160087.1_49825001_2 - 0.18 11.8 22.8 0.13 12.3 8.9 2.9 3 0 0 3 3 3 0 B-box zinc finger Apc13p PF05839.9 001190866.1_29622001_3 - 2.6e-19 69.1 0.3 4e-19 68.5 0.3 1.3 1 0 0 1 1 1 1 Apc13p protein Ion_trans PF00520.29 001145868.1_49826001_1 - 1.5e-31 109.4 13.9 2.3e-31 108.8 13.9 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.9 001145868.1_49826001_1 - 2.8e-28 97.8 0.8 5.9e-28 96.8 0.8 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_4 PF13637.4 001145868.1_49826001_1 - 9.5e-10 38.7 0.0 0.00059 20.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.5 001145868.1_49826001_1 - 1e-09 38.7 0.5 3.9e-05 24.0 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.4 001145868.1_49826001_1 - 2.1e-06 27.5 2.5 0.15 12.5 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.28 001145868.1_49826001_1 - 9.3e-05 22.6 0.4 0.69 10.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.4 001145868.1_49826001_1 - 0.0003 20.9 0.0 3.1 8.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.10 001145868.1_49826001_1 - 0.0018 16.9 14.2 0.03 12.9 14.2 2.3 1 1 0 1 1 1 1 Polycystin cation channel PX PF00787.22 001169007.1_40423001_1 - 9.2e-17 60.9 0.5 1.4e-16 60.3 0.5 1.3 1 0 0 1 1 1 1 PX domain MIT PF04212.16 001169007.1_40423001_1 - 1.1e-14 54.1 0.1 1.8e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Gloverin PF10793.7 001169007.1_40423001_1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Gloverin-like protein Crystall PF00030.17 001173072.1_09922001_1 - 5.7e-57 189.7 1.8 9.3e-28 96.1 0.1 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001173072.1_09922001_1 - 0.00078 19.2 1.6 0.46 10.3 0.1 3.2 1 1 1 2 2 2 2 Peptidase inhibitor family I36 LRR_8 PF13855.4 001135930.1_39526001_1 - 2.2e-53 177.7 56.4 9.8e-13 47.5 1.8 10.4 3 3 8 12 12 12 12 Leucine rich repeat TIR PF01582.18 001135930.1_39526001_1 - 6.7e-33 113.8 0.1 1.2e-32 113.0 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001135930.1_39526001_1 - 1.3e-31 107.8 53.3 1.8e-07 31.1 1.0 10.2 6 2 2 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001135930.1_39526001_1 - 2.5e-14 51.3 49.8 0.41 11.2 0.0 15.8 15 1 0 15 15 15 5 Leucine Rich Repeat LRR_9 PF14580.4 001135930.1_39526001_1 - 3.9e-11 42.6 18.8 0.0013 18.1 0.1 5.0 2 2 3 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.4 001135930.1_39526001_1 - 7.9e-10 38.7 10.9 6.6e-05 22.7 0.1 4.7 2 2 3 5 5 5 3 Leucine rich repeats (6 copies) TIR_2 PF13676.4 001135930.1_39526001_1 - 5e-09 36.3 0.1 9e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001135930.1_39526001_1 - 2.3e-07 30.2 50.1 0.33 11.0 0.4 13.2 14 0 0 14 14 14 3 Leucine Rich repeat DUF1863 PF08937.9 001135930.1_39526001_1 - 3.9e-05 23.8 0.3 0.00015 21.9 0.3 1.9 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) CBP_BcsR PF10945.6 001135930.1_39526001_1 - 0.27 10.6 1.7 0.87 9.0 0.2 2.7 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR Hormone_recep PF00104.28 001190253.1_49825001_3 - 1.4e-39 135.7 0.1 2.1e-39 135.1 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Uteroglobin PF01099.15 001195315.1_39522001_1 - 6.1e-06 26.2 0.0 8.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Uteroglobin family NACHT PF05729.10 001114109.1_29627001_2 - 2.4e-21 76.2 0.0 7.1e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain PYRIN PF02758.14 001114109.1_29627001_2 - 2.9e-15 56.1 1.0 9.4e-15 54.5 1.0 2.0 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain LRR_6 PF13516.4 001114109.1_29627001_2 - 0.00027 20.6 29.6 0.0058 16.5 0.1 9.2 10 0 0 10 10 10 3 Leucine Rich repeat Arteri_nucleo PF01481.14 001114109.1_29627001_2 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein SSF PF00474.15 001168789.1_40425001_1 - 8.4e-157 522.1 24.8 1.1e-156 521.7 24.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Pkinase PF00069.23 001082213.1_37925001_3 - 2.3e-54 184.4 0.1 4.7e-54 183.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001082213.1_37925001_3 - 6.5e-36 123.8 0.1 5.5e-35 120.8 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase dsrm PF00035.24 001082213.1_37925001_3 - 7.5e-24 84.1 4.5 6.5e-12 45.8 0.1 2.9 3 0 0 3 3 3 2 Double-stranded RNA binding motif Kinase-like PF14531.4 001082213.1_37925001_3 - 0.0029 16.8 0.2 0.013 14.7 0.1 1.9 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.14 001082213.1_37925001_3 - 0.013 15.5 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC1 family DND1_DSRM PF14709.5 001082213.1_37925001_3 - 0.014 15.5 0.4 0.6 10.3 0.0 2.8 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Kdo PF06293.12 001082213.1_37925001_3 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thyroglobulin_1 PF00086.16 001159276.1_39522001_3 - 9.7e-18 63.5 2.2 2.2e-17 62.4 2.2 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001159276.1_39522001_3 - 3.7e-10 40.2 20.9 3.7e-10 40.2 20.9 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein zf-C4 PF00105.16 001033029.1_29623001_1 - 2.8e-28 98.0 16.1 5.6e-28 97.1 16.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001033029.1_29623001_1 - 2.2e-14 53.4 0.0 5.1e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LRR_8 PF13855.4 001135926.1_39526001_1 - 3.2e-59 196.4 64.3 2.1e-13 49.7 4.6 11.8 7 4 4 11 11 11 10 Leucine rich repeat TIR PF01582.18 001135926.1_39526001_1 - 2.8e-31 108.5 1.2 2.8e-31 108.5 1.2 1.7 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.5 001135926.1_39526001_1 - 4.4e-21 74.4 66.4 4.4e-05 23.6 3.5 11.8 5 2 10 15 15 15 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001135926.1_39526001_1 - 2.5e-12 46.8 3.5 5.7e-07 29.4 0.3 4.4 5 1 1 6 6 6 3 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001135926.1_39526001_1 - 4.2e-07 29.5 17.9 0.096 12.1 1.3 5.7 2 2 4 6 6 6 4 Leucine-rich repeat TIR_2 PF13676.4 001135926.1_39526001_1 - 8.9e-07 29.1 0.0 7.2e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 TIR domain LRR_6 PF13516.4 001135926.1_39526001_1 - 3.6e-06 26.5 41.1 1.5 9.0 0.2 13.2 15 0 0 15 15 15 3 Leucine Rich repeat LRR_1 PF00560.31 001135926.1_39526001_1 - 1.2e-05 24.9 49.5 1.4 9.6 0.4 14.4 13 3 0 13 13 13 3 Leucine Rich Repeat Aa_trans PF01490.16 001163071.1_37925001_1 - 1.7e-89 300.2 34.0 2.2e-89 299.9 34.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Interferon PF00143.17 001164857.1_49822001_1 - 5.7e-58 195.5 6.6 6.7e-58 195.3 6.6 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Mit_KHE1 PF10173.7 001164857.1_49822001_1 - 0.029 14.3 0.6 0.036 14.0 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Flt3_lig PF02947.12 001078660.1_39522001_1 - 1.8e-66 222.1 0.8 2.4e-66 221.7 0.8 1.1 1 0 0 1 1 1 1 flt3 ligand FixS PF03597.13 001078660.1_39522001_1 - 0.15 11.7 0.8 0.34 10.5 0.8 1.6 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF4381 PF14316.4 001078660.1_39522001_1 - 5.1 7.2 9.0 0.088 12.9 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Orexin PF02072.13 001078660.1_39522001_1 - 6.8 6.5 9.2 23 4.8 0.2 2.8 3 0 0 3 3 3 0 Prepro-orexin zf-C4 PF00105.16 001172731.1_09924001_1 - 2.2e-32 111.2 16.2 2.2e-32 111.2 16.2 2.1 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001172731.1_09924001_1 - 8.3e-25 87.5 0.6 1.7e-24 86.4 0.0 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor 7tm_1 PF00001.19 001173112.1_09924001_1 - 2.4e-78 263.0 2.3 3.2e-78 262.5 2.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001173112.1_09924001_1 - 6.1e-07 28.9 12.4 1.2e-06 28.0 3.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001173112.1_09924001_1 - 6.6e-06 25.5 4.9 6.6e-06 25.5 4.9 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001173112.1_09924001_1 - 3e-05 23.8 1.0 3e-05 23.8 1.0 2.4 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srbc PF10316.7 001173112.1_09924001_1 - 0.00028 20.4 6.7 0.00028 20.4 6.7 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2417 PF10329.7 001173112.1_09924001_1 - 0.12 11.6 6.0 0.23 10.7 3.6 2.2 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Homeobox PF00046.27 001178053.1_39524001_2 - 1.7e-22 78.8 9.2 2.8e-22 78.2 9.2 1.3 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.15 001178053.1_39524001_2 - 1.4e-08 34.1 0.4 2.9e-08 33.1 0.4 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.9 001178053.1_39524001_2 - 0.0028 17.4 0.6 0.0079 16.0 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain PAS_11 PF14598.4 001129734.1_39524001_1 - 3.8e-26 91.3 0.2 3e-22 78.7 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 001129734.1_39524001_1 - 5.7e-21 74.5 0.0 2.5e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.10 001129734.1_39524001_1 - 5.2e-20 71.4 0.0 7.2e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.24 001129734.1_39524001_1 - 1.7e-17 62.9 0.8 3.3e-17 62.0 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001129734.1_39524001_1 - 1e-08 35.2 0.0 4.6e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001129734.1_39524001_1 - 2.2e-05 24.5 0.0 0.008 16.3 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.9 001129734.1_39524001_1 - 0.022 15.3 0.0 0.087 13.4 0.0 1.9 2 0 0 2 2 2 0 PAS fold GAS PF13851.4 001144845.1_49822001_2 - 0.00081 18.7 7.5 0.0014 17.9 7.5 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.19 001144845.1_49822001_2 - 0.0028 17.6 14.3 0.0047 16.9 14.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001144845.1_49822001_2 - 0.0088 16.0 18.6 0.018 15.0 18.6 1.6 1 1 0 1 1 1 1 Basic region leucine zipper DUF1640 PF07798.9 001144845.1_49822001_2 - 0.0089 16.0 0.9 0.012 15.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DivIC PF04977.13 001144845.1_49822001_2 - 0.018 14.7 6.7 0.038 13.6 6.7 1.5 1 0 0 1 1 1 0 Septum formation initiator Tmemb_cc2 PF10267.7 001144845.1_49822001_2 - 0.044 12.8 5.2 0.051 12.6 5.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Kinetocho_Slk19 PF12709.5 001144845.1_49822001_2 - 0.066 13.5 3.0 0.13 12.6 3.0 1.4 1 0 0 1 1 1 0 Central kinetochore-associated C_Hendra PF16821.3 001144845.1_49822001_2 - 0.069 12.9 6.9 0.11 12.2 6.9 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses GIT_CC PF16559.3 001144845.1_49822001_2 - 0.071 13.0 1.5 0.16 11.9 1.5 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Phlebovirus_NSM PF07246.9 001144845.1_49822001_2 - 0.083 12.1 0.6 0.097 11.9 0.6 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CLZ PF16526.3 001144845.1_49822001_2 - 0.089 13.0 7.6 0.17 12.1 7.6 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MAJIN PF15077.4 001144845.1_49822001_2 - 0.16 11.7 6.2 0.21 11.3 6.2 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4407 PF14362.4 001144845.1_49822001_2 - 0.21 10.8 2.5 0.24 10.6 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4613 PF15390.4 001144845.1_49822001_2 - 0.22 9.7 3.5 0.26 9.5 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF5094 PF17015.3 001144845.1_49822001_2 - 0.29 11.1 3.7 0.4 10.6 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Neur_chan_memb PF02932.14 001144845.1_49822001_2 - 0.37 10.7 2.1 0.42 10.5 2.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APG6 PF04111.10 001144845.1_49822001_2 - 0.49 9.6 8.6 0.65 9.2 8.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1003 PF06210.9 001144845.1_49822001_2 - 0.71 9.9 5.2 1.5 8.8 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) bZIP_Maf PF03131.15 001144845.1_49822001_2 - 0.81 10.1 14.5 1.3 9.4 14.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor CDC45 PF02724.12 001144845.1_49822001_2 - 0.92 7.6 8.1 0.99 7.5 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein AC_N PF16214.3 001144845.1_49822001_2 - 1 8.3 5.1 1.2 8.1 5.1 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region RR_TM4-6 PF06459.10 001144845.1_49822001_2 - 1.1 9.0 8.2 1.2 8.7 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HemX PF04375.12 001144845.1_49822001_2 - 1.1 8.3 7.9 1.5 7.9 7.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase IncA PF04156.12 001144845.1_49822001_2 - 1.2 8.8 10.3 0.53 9.9 8.0 1.6 2 0 0 2 2 2 0 IncA protein eIF3_subunit PF08597.8 001144845.1_49822001_2 - 1.3 8.7 14.2 2.1 8.1 14.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DASH_Spc19 PF08287.9 001144845.1_49822001_2 - 1.7 8.4 12.1 1.4 8.7 10.9 1.4 2 0 0 2 2 1 0 Spc19 Bap31 PF05529.10 001144845.1_49822001_2 - 2.9 7.3 5.5 4.1 6.8 5.5 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like LRR_8 PF13855.4 001173029.1_09927001_2 - 7.5e-83 272.1 125.7 9.3e-15 54.0 5.2 11.9 4 3 7 13 13 13 12 Leucine rich repeat LRR_4 PF12799.5 001173029.1_09927001_2 - 2.9e-30 103.6 110.6 2.5e-05 24.4 4.0 14.7 8 2 8 17 17 17 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001173029.1_09927001_2 - 4.8e-24 84.6 17.0 7.4e-07 29.1 2.9 5.9 4 2 1 5 5 5 5 Leucine rich repeats (6 copies) LRR_1 PF00560.31 001173029.1_09927001_2 - 4.3e-11 41.5 77.8 1.4 9.6 0.1 19.7 19 1 0 19 19 19 6 Leucine Rich Repeat TIR PF01582.18 001173029.1_09927001_2 - 1.5e-10 41.0 0.3 2.7e-10 40.2 0.3 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001173029.1_09927001_2 - 1.1e-09 37.9 33.4 0.0045 16.4 2.5 7.0 1 1 7 8 8 8 7 Leucine-rich repeat TIR_2 PF13676.4 001173029.1_09927001_2 - 0.0085 16.3 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.16 001173029.1_09927001_2 - 0.0092 15.5 0.9 0.017 14.6 0.2 1.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.4 001173029.1_09927001_2 - 0.16 11.9 93.9 0.94 9.6 0.1 18.3 21 0 0 21 21 21 0 Leucine Rich repeat LRR_8 PF13855.4 001135928.1_39526001_2 - 1.8e-83 274.1 91.8 8.3e-16 57.4 4.7 11.5 5 5 3 10 10 10 10 Leucine rich repeat LRR_4 PF12799.5 001135928.1_39526001_2 - 6.3e-37 124.7 101.4 5.2e-05 23.4 4.4 13.6 7 3 7 15 15 15 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001135928.1_39526001_2 - 8.1e-24 83.9 18.2 1.6e-05 24.7 0.2 5.9 2 1 2 5 5 5 4 Leucine rich repeats (6 copies) LRR_1 PF00560.31 001135928.1_39526001_2 - 2.1e-12 45.5 83.9 0.5 10.9 0.2 19.7 20 1 0 20 20 20 8 Leucine Rich Repeat LRR_9 PF14580.4 001135928.1_39526001_2 - 3.8e-11 42.7 37.0 3.5e-05 23.2 0.7 8.1 2 1 7 9 9 9 6 Leucine-rich repeat TIR PF01582.18 001135928.1_39526001_2 - 3.1e-10 40.0 0.4 5.3e-10 39.3 0.4 1.3 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001135928.1_39526001_2 - 5.6e-07 29.0 85.3 0.48 10.5 0.1 18.8 20 0 0 20 20 20 9 Leucine Rich repeat TIR_2 PF13676.4 001135928.1_39526001_2 - 0.0034 17.5 0.1 0.0065 16.6 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.16 001135928.1_39526001_2 - 0.014 14.9 0.6 0.014 14.9 0.6 2.1 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain zf-C4 PF00105.16 001190276.1_49825001_1 - 3e-31 107.6 17.5 5.1e-31 106.8 17.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001190276.1_49825001_1 - 2.1e-30 105.7 0.0 3.8e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Gtr1_RagA PF04670.10 001161867.1_39523001_1 - 6.5e-73 244.8 0.9 8.5e-73 244.4 0.9 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.11 001161867.1_39523001_1 - 4.7e-05 23.5 0.0 7.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001161867.1_39523001_1 - 7e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001161867.1_39523001_1 - 0.00036 19.9 0.0 0.0006 19.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.20 001161867.1_39523001_1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.4 001161867.1_39523001_1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.4 001161867.1_39523001_1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.21 001161867.1_39523001_1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase TIR_2 PF13676.4 001130435.1_29622001_1 - 5.3e-11 42.6 0.0 7.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001130435.1_29622001_1 - 2.3e-06 27.4 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 TIR domain Crystallin PF00525.16 001173076.1_09922001_3 - 3.4e-29 100.7 7.5 6.6e-29 99.8 7.5 1.5 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.19 001173076.1_09922001_3 - 6.6e-25 87.1 0.1 8.6e-25 86.7 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Frag1 PF10277.7 001190286.1_49822001_3 - 8.6e-50 169.2 18.0 1e-49 168.9 18.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Phage_holin_4_2 PF04020.11 001190286.1_49822001_3 - 0.065 13.8 9.0 0.19 12.3 2.3 2.9 1 1 2 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV HRG PF16954.3 001190286.1_49822001_3 - 0.096 13.0 0.5 0.096 13.0 0.5 3.5 5 0 0 5 5 5 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Pho86 PF11124.6 001190286.1_49822001_3 - 0.75 9.1 4.5 0.3 10.4 1.5 1.7 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Bacteriocin_IId PF09221.8 001190286.1_49822001_3 - 9.9 6.3 8.3 0.53 10.4 0.1 2.9 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like PIG-U PF06728.11 001185136.1_49823001_1 - 5.6e-115 384.3 45.3 6.6e-115 384.1 45.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U OATP PF03137.18 001038021.1_39526001_1 - 4.6e-172 573.0 15.3 5.5e-172 572.7 15.3 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.14 001038021.1_39526001_1 - 6e-21 74.6 37.7 9.9e-21 73.9 26.1 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.13 001038021.1_39526001_1 - 4.3e-07 29.9 3.7 9.2e-07 28.8 3.7 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.19 001038021.1_39526001_1 - 0.001 18.9 2.3 0.0024 17.7 2.3 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain LRR_8 PF13855.4 001128484.1_49823001_1 - 5.9e-20 70.7 28.5 5.2e-07 29.2 0.2 4.0 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.5 001128484.1_49823001_1 - 4.3e-15 55.4 24.3 1.6e-06 28.1 4.3 4.9 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001128484.1_49823001_1 - 0.007 16.5 15.8 1.2 9.7 0.7 5.9 7 0 0 7 7 7 2 Leucine Rich Repeat PPR PF01535.18 001128484.1_49823001_1 - 0.13 12.5 0.0 0.55 10.5 0.0 2.2 1 0 0 1 1 1 0 PPR repeat PPR_1 PF12854.5 001128484.1_49823001_1 - 0.15 11.7 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 PPR repeat LRR_6 PF13516.4 001128484.1_49823001_1 - 7.6 6.7 15.3 26 5.1 0.2 5.5 6 0 0 6 6 6 0 Leucine Rich repeat RAMP PF04901.11 214082.1_49822001_3 - 3.1e-40 136.5 0.6 4.3e-40 136.0 0.6 1.2 1 0 0 1 1 1 1 Receptor activity modifying family PAS_3 PF08447.10 001173054.1_09926001_2 - 6.5e-20 71.1 0.2 1.4e-13 50.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001173054.1_09926001_2 - 3.7e-15 55.9 0.1 5.9e-12 45.6 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.23 001173054.1_09926001_2 - 5.2e-15 55.3 0.1 2.5e-13 49.9 0.0 2.8 3 0 0 3 3 3 1 PAS fold HLH PF00010.24 001173054.1_09926001_2 - 1.2e-05 25.1 0.2 2.5e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001173054.1_09926001_2 - 0.054 13.6 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 PAS domain PAS_4 PF08448.8 001173054.1_09926001_2 - 0.13 12.3 0.1 0.95 9.6 0.0 2.2 2 0 0 2 2 2 0 PAS fold Prenyltrans PF00432.19 001161868.1_39523001_3 - 1.7e-64 213.1 16.7 1.2e-15 56.8 0.1 6.1 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.4 001161868.1_39523001_3 - 0.0006 18.9 0.0 0.00098 18.2 0.0 1.2 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.4 001161868.1_39523001_3 - 0.025 13.6 0.0 0.63 9.0 0.0 2.7 3 0 0 3 3 3 0 Squalene-hopene cyclase N-terminal domain Crystall PF00030.17 001173078.1_09922001_2 - 1e-58 195.3 3.5 1.8e-29 101.6 0.2 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001173078.1_09922001_2 - 6.4e-09 35.5 0.0 3.5e-05 23.5 0.0 2.6 2 1 0 2 2 2 2 Peptidase inhibitor family I36 Crystall_3 PF08964.8 001173078.1_09922001_2 - 0.0027 17.7 0.6 0.54 10.3 0.0 3.1 2 1 1 3 3 3 1 Beta/Gamma crystallin SprB PF13573.4 001173078.1_09922001_2 - 0.84 9.3 3.8 23 4.7 3.8 2.3 1 1 0 1 1 1 0 SprB repeat SSF PF00474.15 001168773.1_40424001_1 - 1.3e-174 580.7 23.6 1.3e-174 580.7 23.6 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family HAMP PF00672.23 001168773.1_40424001_1 - 4.6 7.4 0.0 4.6 7.4 0.0 4.2 5 0 0 5 5 5 0 HAMP domain ANTH PF07651.14 001082156.1_37927001_1 - 2.2e-78 262.9 6.7 8.5e-76 254.4 0.0 2.6 2 0 0 2 2 2 2 ANTH domain I_LWEQ PF01608.15 001082156.1_37927001_1 - 1.9e-52 177.4 6.4 1.9e-52 177.4 6.4 4.8 3 1 2 5 5 5 1 I/LWEQ domain HIP1_clath_bdg PF16515.3 001082156.1_37927001_1 - 5.2e-30 103.9 21.2 5.2e-30 103.9 21.2 5.9 5 1 1 6 6 6 1 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.10 001082156.1_37927001_1 - 6.9 7.1 13.4 13 6.2 1.6 5.1 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein COPI_C PF06957.9 001132892.1_43527001_3 - 1.1e-188 626.9 0.0 1.5e-188 626.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.12 001132892.1_43527001_3 - 1.5e-143 478.9 0.9 2.2e-143 478.4 0.9 1.2 1 0 0 1 1 1 1 Coatomer WD associated region TPR_14 PF13428.4 001132892.1_43527001_3 - 0.011 16.4 0.1 1.4 9.8 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.15 001132892.1_43527001_3 - 0.15 12.1 0.0 20 5.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SSF PF00474.15 001171357.1_37924001_1 - 3.2e-161 536.6 19.6 3.2e-161 536.6 19.6 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family Pectate_lyase22 PF14583.4 001171357.1_37924001_3 - 0.088 11.3 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Oligogalacturonate lyase Crystall PF00030.17 001173070.1_09922001_1 - 9e-57 189.1 0.1 2e-27 95.1 0.1 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001173070.1_09922001_1 - 0.00067 19.4 0.0 0.35 10.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase inhibitor family I36 CD36 PF01130.19 001082788.1_37925001_2 - 2.6e-154 514.1 0.1 3e-154 513.8 0.1 1.0 1 0 0 1 1 1 1 CD36 family Mito_carr PF00153.25 001127287.1_39522001_1 - 2.3e-21 75.4 0.1 3.1e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein AA_permease_2 PF13520.4 001082061.1_37924001_2 - 1.2e-60 205.5 46.6 1.5e-60 205.1 46.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.19 001082061.1_37924001_2 - 8.2e-23 80.6 42.0 1.3e-22 79.9 42.0 1.2 1 0 0 1 1 1 1 Amino acid permease PhrC_PhrF PF11131.6 001082061.1_37924001_2 - 0.087 12.3 1.1 0.36 10.3 1.1 2.1 1 0 0 1 1 1 0 Rap-phr extracellular signalling DUF3098 PF11297.6 001082061.1_37924001_2 - 6 6.4 14.5 0.79 9.2 1.4 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) TSGP1 PF07771.9 001082061.1_37924001_2 - 7 6.7 10.5 14 5.8 10.5 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 LRR_8 PF13855.4 001097434.1_49828001_1 - 1.1e-67 223.6 99.7 5.7e-10 38.7 5.8 15.1 11 3 3 14 14 14 14 Leucine rich repeat LRR_4 PF12799.5 001097434.1_49828001_1 - 1.7e-33 113.8 105.8 3.9e-06 26.9 3.5 16.2 8 4 6 16 16 16 14 Leucine Rich repeats (2 copies) TIR PF01582.18 001097434.1_49828001_1 - 1.2e-12 47.8 0.2 2e-12 47.1 0.2 1.3 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.4 001097434.1_49828001_1 - 1.1e-10 41.4 25.1 0.00057 19.7 0.8 6.8 5 1 2 7 7 7 3 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001097434.1_49828001_1 - 1.8e-07 30.7 44.1 0.0042 16.5 5.3 7.7 3 3 5 8 8 8 5 Leucine-rich repeat LRR_1 PF00560.31 001097434.1_49828001_1 - 1.4e-06 27.8 84.4 2.5 8.8 0.9 21.2 20 3 1 21 21 21 5 Leucine Rich Repeat LRR_6 PF13516.4 001097434.1_49828001_1 - 3.3e-05 23.5 65.2 0.84 9.7 0.1 17.6 19 0 0 19 19 19 3 Leucine Rich repeat TIR_2 PF13676.4 001097434.1_49828001_1 - 0.00077 19.6 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain CARD PF00619.19 001132464.1_43529001_2 - 9.7e-24 83.1 0.1 1.4e-22 79.4 0.0 2.7 2 0 0 2 2 2 1 Caspase recruitment domain Guanylate_kin PF00625.19 001132464.1_43529001_2 - 0.00012 21.7 0.0 0.00033 20.2 0.0 1.7 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.22 001132464.1_43529001_2 - 0.053 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Y_phosphatase PF00102.25 001132464.1_43529001_2 - 0.16 11.4 1.3 0.29 10.5 1.3 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3584 PF12128.6 001132464.1_43529001_2 - 7.1 3.9 33.7 13 3.0 33.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HMG_box_2 PF09011.8 001163679.1_32322001_3 - 4.3e-49 164.8 10.5 6.2e-30 103.5 6.2 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.17 001163679.1_32322001_3 - 1.1e-42 144.1 10.0 1.1e-27 96.2 0.2 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.4 001163679.1_32322001_3 - 0.0016 18.2 11.3 0.11 12.4 1.7 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Ribosomal_60s PF00428.17 001163679.1_32322001_3 - 0.0046 17.4 15.4 0.011 16.1 15.4 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1074 PF06382.9 001163679.1_32322001_3 - 0.047 13.8 5.0 0.26 11.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1074) YABBY PF04690.11 001163679.1_32322001_3 - 1.7 9.0 5.8 0.59 10.6 0.5 2.5 1 1 2 3 3 3 0 YABBY protein TGFb_propeptide PF00688.16 001082660.1_37923001_1 - 1.4e-33 116.6 0.6 1e-32 113.7 0.6 2.0 1 1 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 001082660.1_37923001_1 - 3.2e-24 85.7 1.4 8.5e-24 84.3 1.4 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain RNase_H_2 PF13482.4 001082660.1_37923001_1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily SPEG_u2 PF16650.3 001082660.1_37923001_1 - 0.44 10.6 3.6 0.16 12.0 0.5 1.8 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein Ras PF00071.20 001077230.2_49825001_1 - 1.5e-50 170.8 0.0 1.9e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001077230.2_49825001_1 - 1.1e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001077230.2_49825001_1 - 2.7e-08 33.3 0.0 3.7e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001077230.2_49825001_1 - 0.047 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.10 001161864.1_39522001_1 - 4.7e-109 363.0 0.8 5.7e-109 362.7 0.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.20 001161864.1_39522001_1 - 9.5e-09 34.9 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001161864.1_39522001_1 - 1.1e-08 35.2 0.0 3.8e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001161864.1_39522001_1 - 2.8e-08 33.3 0.1 5.6e-08 32.3 0.0 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001161864.1_39522001_1 - 9.9e-07 28.7 0.0 3.2e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001161864.1_39522001_1 - 0.0018 17.7 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001161864.1_39522001_1 - 0.0054 16.0 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF815 PF05673.11 001161864.1_39522001_1 - 0.011 14.8 1.7 0.16 11.0 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.7 001161864.1_39522001_1 - 0.024 14.3 0.2 0.084 12.5 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.25 001161864.1_39522001_1 - 0.027 14.8 0.1 0.076 13.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.14 001161864.1_39522001_1 - 0.035 13.9 0.1 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SecA_DEAD PF07517.12 001161864.1_39522001_1 - 0.048 12.8 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_24 PF13479.4 001161864.1_39522001_1 - 0.071 12.7 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.4 001161864.1_39522001_1 - 0.2 11.3 0.4 0.4 10.3 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.18 001161864.1_39522001_1 - 0.82 8.6 7.7 3.6 6.5 0.7 2.9 2 1 1 3 3 3 0 G-protein alpha subunit DUF5099 PF17025.3 001161864.1_39522001_1 - 1.6 9.1 5.0 17 5.7 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5099) V-set PF07686.15 001135916.1_45723001_2 - 1.2e-12 47.8 0.0 2.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001135916.1_45723001_2 - 4.1e-08 33.6 0.0 3.7e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.14 001135916.1_45723001_2 - 0.00018 21.4 0.0 0.00067 19.5 0.0 2.0 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.4 001135916.1_45723001_2 - 0.00043 20.4 0.0 0.17 12.1 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001135916.1_45723001_2 - 0.00074 19.5 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ndc1_Nup PF09531.8 001135916.1_45723001_2 - 0.0036 15.9 4.3 0.0047 15.5 4.3 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup C2-set_2 PF08205.10 001135916.1_45723001_2 - 0.011 15.7 0.1 0.062 13.2 0.0 2.1 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Crystall PF00030.17 001173077.1_09922001_2 - 8.5e-55 182.8 2.9 4.9e-28 97.0 0.0 2.4 3 0 0 3 3 3 2 Beta/Gamma crystallin DUF2914 PF11141.6 001173077.1_09922001_2 - 0.015 14.9 0.1 0.039 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) MatE PF01554.16 001134066.1_43525001_1 - 1.7e-54 183.7 25.6 9.9e-32 109.7 4.6 3.7 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.4 001134066.1_43525001_1 - 2.2e-07 30.9 10.0 2.2e-07 30.9 10.0 3.9 4 1 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain DUF2681 PF10883.6 001134066.1_43525001_1 - 0.0028 17.9 0.5 0.0073 16.6 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Sugar_tr PF00083.22 001168756.1_40424001_1 - 1.5e-26 93.1 22.1 2.5e-26 92.4 22.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001168756.1_40424001_1 - 6.1e-19 68.0 42.2 1.8e-12 46.8 21.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Bcl-2 PF00452.17 001082135.1_37922001_1 - 9.7e-35 119.0 0.1 1.5e-34 118.4 0.1 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.15 001082135.1_37922001_1 - 1.5e-14 53.3 0.3 2.5e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.4 001082135.1_37922001_1 - 0.015 15.8 0.0 0.021 15.4 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Nitrate_red_del PF02613.13 001082135.1_37922001_1 - 0.11 12.4 0.0 0.43 10.5 0.0 1.9 1 1 1 2 2 2 0 Nitrate reductase delta subunit LRR_8 PF13855.4 214187.1_49828001_1 - 6.9e-75 246.6 105.5 1.7e-08 34.0 0.7 15.3 9 5 5 15 15 15 15 Leucine rich repeat LRR_4 PF12799.5 214187.1_49828001_1 - 8.2e-44 146.6 98.2 2.6e-06 27.5 1.0 15.0 9 4 8 17 17 17 16 Leucine Rich repeats (2 copies) TIR PF01582.18 214187.1_49828001_1 - 5.6e-14 52.2 2.1 1.2e-13 51.1 0.7 2.0 2 0 0 2 2 2 1 TIR domain LRR_1 PF00560.31 214187.1_49828001_1 - 6.4e-14 50.1 83.2 0.04 14.2 0.7 21.7 22 2 0 22 22 22 7 Leucine Rich Repeat LRR_5 PF13306.4 214187.1_49828001_1 - 2.7e-10 40.2 24.1 0.04 13.7 1.5 7.3 4 2 2 8 8 8 5 Leucine rich repeats (6 copies) LRR_9 PF14580.4 214187.1_49828001_1 - 2.2e-07 30.4 38.5 0.13 11.6 0.7 7.7 3 3 2 7 7 7 6 Leucine-rich repeat TIR_2 PF13676.4 214187.1_49828001_1 - 1.4e-05 25.3 0.1 3e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 TIR domain Thioredoxin PF00085.18 001163046.1_39524001_1 - 2.4e-69 229.7 4.8 2.4e-23 81.9 0.0 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_2 PF13098.4 001163046.1_39524001_1 - 2.7e-23 82.4 7.2 8.8e-07 29.2 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.4 001163046.1_39524001_1 - 1.7e-18 66.4 1.3 4.6e-06 26.6 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin-like AhpC-TSA PF00578.19 001163046.1_39524001_1 - 1.3e-15 57.3 2.1 2.5e-05 24.0 0.1 3.8 4 0 0 4 4 4 3 AhpC/TSA family OST3_OST6 PF04756.11 001163046.1_39524001_1 - 2.9e-14 53.0 0.5 3.4e-06 26.5 0.0 3.1 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.4 001163046.1_39524001_1 - 1.5e-13 50.7 2.1 0.0014 18.8 0.3 4.6 4 2 1 5 5 4 3 Thioredoxin-like Redoxin PF08534.8 001163046.1_39524001_1 - 1.6e-13 50.5 0.5 0.00059 19.4 0.0 3.4 3 0 0 3 3 3 3 Redoxin Thioredoxin_6 PF13848.4 001163046.1_39524001_1 - 7.6e-10 38.9 2.9 0.001 18.9 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin-like domain TraF PF13728.4 001163046.1_39524001_1 - 2.9e-08 33.7 0.2 0.033 13.9 0.0 3.8 3 1 0 3 3 3 3 F plasmid transfer operon protein Thioredoxin_9 PF14595.4 001163046.1_39524001_1 - 2.8e-07 30.2 0.2 0.63 9.7 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin HyaE PF07449.9 001163046.1_39524001_1 - 0.00028 20.7 0.0 0.93 9.4 0.0 3.7 3 1 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.4 001163046.1_39524001_1 - 0.0028 17.5 0.4 1.5 8.8 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin domain DUF2847 PF11009.6 001163046.1_39524001_1 - 0.0074 16.0 0.1 5.4 6.9 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF2847) Glutaredoxin PF00462.22 001163046.1_39524001_1 - 0.014 15.5 9.8 1.1 9.4 0.5 4.0 4 0 0 4 4 3 0 Glutaredoxin Thioredoxin_4 PF13462.4 001163046.1_39524001_1 - 2.9 7.9 6.8 29 4.6 1.3 3.3 3 0 0 3 3 3 0 Thioredoxin Spc97_Spc98 PF04130.11 001171310.1_37924001_1 - 1e-108 364.3 11.5 1.2e-108 364.1 11.5 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family IFN-gamma PF00714.15 001172874.1_09923001_3 - 7.1e-62 207.2 10.3 1.1e-61 206.6 10.3 1.3 1 0 0 1 1 1 1 Interferon gamma API5 PF05918.9 001172874.1_09923001_3 - 0.0063 15.3 3.9 0.42 9.3 0.2 2.1 1 1 1 2 2 2 2 Apoptosis inhibitory protein 5 (API5) I-set PF07679.14 001171485.1_37929001_1 - 1.2e-190 618.1 0.0 1e-17 63.8 0.0 19.3 19 0 0 19 19 19 19 Immunoglobulin I-set domain Ig_3 PF13927.4 001171485.1_37929001_1 - 4.7e-148 482.0 0.0 7.8e-11 42.3 0.0 18.9 19 0 0 19 19 19 16 Immunoglobulin domain Ig_2 PF13895.4 001171485.1_37929001_1 - 9.9e-97 317.3 0.0 1.2e-07 31.9 0.0 17.4 16 1 0 17 17 17 12 Immunoglobulin domain ig PF00047.23 001171485.1_37929001_1 - 3.3e-93 305.9 0.0 6.4e-08 32.5 0.0 18.9 19 0 0 19 19 19 13 Immunoglobulin domain V-set PF07686.15 001171485.1_37929001_1 - 8.3e-47 157.7 16.1 0.0061 16.6 0.0 24.4 16 11 4 21 21 21 11 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001171485.1_37929001_1 - 1.7e-26 92.0 5.2 0.0014 18.5 0.0 14.9 17 0 0 17 17 16 5 Izumo-like Immunoglobulin domain Ig_5 PF16681.3 001171485.1_37929001_1 - 9.5e-24 83.5 0.0 0.5 10.7 0.0 13.9 13 1 0 13 13 12 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.10 001171485.1_37929001_1 - 1e-18 67.0 13.1 0.23 11.4 0.0 13.0 14 0 0 14 14 13 4 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.10 001171485.1_37929001_1 - 1.7e-16 59.9 4.0 0.063 13.2 0.1 10.3 11 0 0 11 11 10 4 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.3 001171485.1_37929001_1 - 5.1e-16 58.7 1.9 6.3 7.1 0.1 13.3 14 2 0 14 14 14 3 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.13 001171485.1_37929001_1 - 2.6e-11 43.7 0.0 18 5.7 0.0 10.9 12 0 0 12 12 11 0 Immunoglobulin C1-set domain fn3 PF00041.19 001171485.1_37929001_1 - 0.00068 19.8 0.0 0.0022 18.2 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain Receptor_2B4 PF11465.6 001171485.1_37929001_1 - 0.00068 19.7 0.0 5.2 7.2 0.0 6.1 7 0 0 7 7 7 1 Natural killer cell receptor 2B4 Herpes_gE PF02480.14 001171485.1_37929001_1 - 0.00068 18.4 0.0 1.9 7.0 0.0 4.8 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein E DUF2914 PF11141.6 001171485.1_37929001_1 - 0.18 11.5 0.4 1.3e+02 2.3 0.0 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF2914) PKD_3 PF16820.3 001171485.1_37929001_1 - 0.51 10.0 5.3 1.6 8.4 0.0 4.5 6 0 0 6 6 6 0 PKD-like domain 7tm_1 PF00001.19 001198936.1_37923001_1 - 4.4e-75 252.2 4.3 5.7e-75 251.9 4.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001198936.1_37923001_1 - 2.1e-06 27.2 14.5 1.2e-05 24.8 6.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001198936.1_37923001_1 - 5.3e-05 23.0 7.3 5.3e-05 23.0 7.3 2.2 2 1 0 2 2 2 1 Olfactory receptor Pkinase_Tyr PF07714.15 001195713.1_29624001_2 - 3.2e-38 131.4 0.0 4.9e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.4 001195713.1_29624001_2 - 2.4e-23 81.7 1.3 2.4e-10 40.4 0.2 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.4 001195713.1_29624001_2 - 3.5e-23 81.5 2.3 5.3e-10 39.5 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Pkinase PF00069.23 001195713.1_29624001_2 - 4.2e-22 78.6 0.0 6.7e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.5 001195713.1_29624001_2 - 1.2e-20 73.7 0.1 1.6e-10 41.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001195713.1_29624001_2 - 5.8e-20 70.7 0.2 4.9e-06 26.6 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.4 001195713.1_29624001_2 - 3e-18 63.9 0.2 5e-06 26.3 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat RasGEF PF00617.17 001195367.1_49824001_3 - 6e-52 176.2 0.3 6e-52 176.2 0.3 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.18 001195367.1_49824001_3 - 6.6e-16 58.3 0.3 2.1e-15 56.7 0.1 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif RabGAP-TBC PF00566.16 001133321.1_43525001_1 - 4.3e-49 166.9 0.3 6.7e-49 166.3 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ELMO_CED12 PF04727.11 001133321.1_43525001_1 - 0.055 13.4 0.1 0.076 13.0 0.1 1.2 1 0 0 1 1 1 0 ELMO/CED-12 family Thyroglobulin_1 PF00086.16 001145177.1_39522001_3 - 1.7e-22 78.7 2.3 2.7e-22 78.1 2.3 1.3 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001145177.1_39522001_3 - 3.5e-08 33.8 20.3 3.5e-08 33.8 20.3 2.1 2 0 0 2 2 2 1 Insulin-like growth factor binding protein DFF-C PF09033.8 001145177.1_39522001_3 - 0.036 13.8 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain HSP90 PF00183.16 001133085.1_43525001_3 - 2.7e-100 336.5 2.0 1.5e-95 320.9 0.6 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.4 001133085.1_43525001_3 - 3.5e-11 42.9 0.0 8.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.24 001133085.1_43525001_3 - 6e-09 36.3 0.1 1.1e-08 35.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thymosin PF01290.18 001193442.1_29621001_1 - 1.6e-22 78.8 6.4 2.2e-22 78.3 6.4 1.2 1 0 0 1 1 1 1 Thymosin beta-4 family DUF4522 PF15022.4 001193442.1_29621001_1 - 0.076 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) WH2 PF02205.18 001193442.1_29621001_1 - 0.08 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 WH2 motif SSF PF00474.15 001171422.1_37925001_1 - 2.8e-164 546.7 25.3 3.8e-164 546.3 25.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Cadherin PF00028.15 199503.1_45729001_1 - 1.6e-75 249.5 0.4 4.9e-19 68.4 0.2 6.3 6 0 0 6 6 6 6 Cadherin domain Cadherin_tail PF15974.3 199503.1_45729001_1 - 1.6e-62 209.6 4.6 1.6e-62 209.6 4.7 1.6 2 0 0 2 2 2 1 Cadherin C-terminal cytoplasmic tail, catenin-binding region Cadherin_2 PF08266.10 199503.1_45729001_1 - 1.4e-29 101.6 3.0 1e-28 98.8 0.1 3.5 4 0 0 4 4 4 1 Cadherin-like Cadherin_C_2 PF16492.3 199503.1_45729001_1 - 3.5e-05 24.4 0.0 9.9e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Cadherin_3 PF16184.3 199503.1_45729001_1 - 0.00015 21.6 5.2 8.7 6.3 0.1 5.0 5 1 1 6 6 6 2 Cadherin-like Mito_carr PF00153.25 001127292.1_39522001_1 - 7.4e-51 169.9 9.8 5.6e-21 74.1 0.3 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein TIR PF01582.18 001164863.1_37924001_1 - 3.5e-37 127.8 0.0 6.4e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.4 001164863.1_37924001_1 - 3.4e-12 46.7 2.3 5.6e-05 23.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.15 001164863.1_37924001_1 - 5.6e-12 45.6 0.4 0.0013 18.7 0.0 4.5 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.4 001164863.1_37924001_1 - 5e-11 42.7 5.0 0.00059 20.0 0.6 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.14 001164863.1_37924001_1 - 1.2e-08 34.8 0.1 0.0043 17.0 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.23 001164863.1_37924001_1 - 1.3e-07 31.6 3.5 0.019 15.0 0.1 3.6 3 1 0 3 3 3 3 Immunoglobulin domain TIR_2 PF13676.4 001164863.1_37924001_1 - 0.0019 18.3 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 TIR domain Ig_5 PF16681.3 001164863.1_37924001_1 - 0.063 13.6 5.3 1.9 8.8 0.1 3.8 3 1 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Crystall PF00030.17 001173071.1_09922001_3 - 2e-59 197.6 0.2 2.6e-30 104.3 0.0 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001173071.1_09922001_3 - 6.4e-06 25.9 0.0 0.029 14.2 0.0 2.5 2 0 0 2 2 2 2 Peptidase inhibitor family I36 Crystall_3 PF08964.8 001173071.1_09922001_3 - 2.5e-05 24.2 0.2 0.18 11.8 0.1 3.3 3 0 0 3 3 3 2 Beta/Gamma crystallin LRR_8 PF13855.4 001130429.1_29626001_1 - 6.1e-60 198.7 60.2 2.3e-13 49.5 5.1 10.8 6 2 3 10 10 10 9 Leucine rich repeat TIR PF01582.18 001130429.1_29626001_1 - 7e-36 123.5 0.7 1.1e-35 122.9 0.7 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001130429.1_29626001_1 - 1.5e-28 98.1 64.8 5.4e-05 23.3 2.8 12.2 6 4 7 13 13 13 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001130429.1_29626001_1 - 3.6e-14 52.7 1.8 1.1e-06 28.5 0.3 4.3 3 2 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_1 PF00560.31 001130429.1_29626001_1 - 2.8e-11 42.1 46.9 0.29 11.6 0.7 15.8 15 2 0 15 15 15 4 Leucine Rich Repeat LRR_9 PF14580.4 001130429.1_29626001_1 - 7.7e-10 38.4 21.0 0.021 14.2 0.6 6.0 2 2 4 6 6 6 5 Leucine-rich repeat LRR_6 PF13516.4 001130429.1_29626001_1 - 1.3e-06 27.8 39.3 1.8 8.7 0.3 13.3 14 0 0 14 14 14 3 Leucine Rich repeat TIR_2 PF13676.4 001130429.1_29626001_1 - 4.6e-06 26.8 0.0 8.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRRCT PF01463.22 001130429.1_29626001_1 - 0.041 14.3 0.0 3.2 8.4 0.0 3.1 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain TPT PF03151.14 001107803.1_45724001_2 - 2.4e-24 86.0 13.0 3e-24 85.7 13.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.18 001107803.1_45724001_2 - 1.5e-06 28.3 38.4 9.2e-06 25.7 11.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.9 001107803.1_45724001_2 - 1.2e-05 24.6 19.2 1.5e-05 24.2 19.2 1.1 1 0 0 1 1 1 1 UAA transporter family SPC25 PF06703.9 001107803.1_45724001_2 - 5.1 6.7 6.2 8.5 6.0 0.6 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Hormone_recep PF00104.28 001171323.1_37923001_1 - 2e-35 122.1 0.0 2.7e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001171323.1_37923001_1 - 5.2e-29 100.4 14.1 1.7e-28 98.8 13.8 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) PBP PF01161.18 001162888.1_49822001_1 - 1.4e-18 67.3 0.0 2e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein hSac2 PF12456.6 001134164.1_43525001_1 - 4.6e-19 68.1 0.0 7.4e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 Inositol phosphatase HMG_box PF00505.17 001171281.1_37922001_1 - 3.6e-42 142.5 13.1 2.7e-27 94.9 0.7 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.8 001171281.1_37922001_1 - 1.3e-41 140.9 21.1 3.1e-27 94.8 8.3 2.8 2 1 1 3 3 3 2 HMG-box domain HMG_box_5 PF14887.4 001171281.1_37922001_1 - 0.0075 16.1 16.1 0.18 11.6 3.2 2.5 2 1 0 2 2 2 2 HMG (high mobility group) box 5 Nop14 PF04147.10 001171281.1_37922001_1 - 0.13 10.3 24.1 0.15 10.1 24.1 1.1 1 0 0 1 1 1 0 Nop14-like family Ets PF00178.20 001171281.1_37922001_1 - 2.1 8.7 5.0 11 6.5 0.4 2.4 2 0 0 2 2 2 0 Ets-domain NOA36 PF06524.10 001171281.1_37922001_1 - 6.4 5.9 25.8 0.3 10.3 20.4 1.5 2 0 0 2 2 2 0 NOA36 protein Nucleo_P87 PF07267.9 001171281.1_37922001_1 - 7.6 5.1 17.3 7 5.2 16.8 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nuc_sug_transp PF04142.13 001127270.1_39522001_1 - 1.1e-29 103.5 2.5 7.8e-29 100.7 2.5 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.18 001127270.1_39522001_1 - 1.9e-06 28.0 24.3 0.0028 17.7 2.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family YL1_C PF08265.9 001127270.1_39522001_1 - 0.14 11.8 0.3 8.4 6.1 0.0 2.6 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain LRR_8 PF13855.4 001135929.1_39527001_1 - 9.1e-76 249.4 98.9 5.2e-10 38.8 9.6 14.5 10 4 4 14 14 14 14 Leucine rich repeat LRR_4 PF12799.5 001135929.1_39527001_1 - 1.3e-42 142.8 95.3 1.5e-05 25.1 0.5 14.9 7 4 7 15 15 15 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001135929.1_39527001_1 - 1.1e-18 64.5 82.2 0.22 12.0 0.1 22.9 22 3 1 23 23 23 8 Leucine Rich Repeat TIR PF01582.18 001135929.1_39527001_1 - 5e-14 52.4 0.9 9.5e-14 51.4 0.9 1.4 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.4 001135929.1_39527001_1 - 5.1e-11 42.5 22.7 0.15 11.9 2.3 8.1 3 2 4 8 8 8 5 Leucine rich repeats (6 copies) TIR_2 PF13676.4 001135929.1_39527001_1 - 3.8e-05 23.8 0.1 8.4e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001135929.1_39527001_1 - 4.4e-05 22.9 36.1 0.46 9.8 0.2 8.3 3 3 6 10 10 10 7 Leucine-rich repeat PRE_C2HC PF07530.9 001135929.1_39527001_1 - 0.2 11.7 0.3 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 Associated with zinc fingers FNIP PF05725.10 001135929.1_39527001_1 - 0.22 11.6 32.0 2.6 8.2 8.0 7.8 6 2 1 7 7 7 0 FNIP Repeat Ammonium_transp PF00909.19 001199791.1_39523001_1 - 4.4e-76 256.0 14.4 5.2e-76 255.8 14.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4293 PF14126.4 001199791.1_39523001_1 - 0.01 16.0 2.8 0.011 15.9 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Tubulin PF00091.23 001195806.1_37924001_2 - 6.7e-69 231.9 0.0 8.9e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001195806.1_37924001_2 - 2.2e-51 173.2 0.0 3.5e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001195806.1_37924001_2 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Hormone_recep PF00104.28 001184956.1_37923001_1 - 4.2e-30 104.7 1.8 7.3e-30 104.0 1.8 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001184956.1_37923001_1 - 4.5e-27 94.2 14.3 9.5e-27 93.1 14.3 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF4632 PF15451.4 001184956.1_37923001_3 - 0.094 12.7 4.1 0.46 10.5 1.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4632) LppC PF04348.11 001184956.1_37923001_3 - 0.22 10.1 0.0 0.3 9.7 0.0 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein Tyrosinase PF00264.18 001130023.1_39524001_3 - 1.5e-35 123.4 0.3 2.8e-35 122.5 0.1 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Laminin_EGF PF00053.22 001130023.1_39524001_3 - 0.018 15.0 3.9 0.018 15.0 3.9 2.8 3 0 0 3 3 3 0 Laminin EGF domain Hormone_recep PF00104.28 001162543.1_39522001_1 - 1.6e-40 138.8 0.1 2.1e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Thyroglobulin_1 PF00086.16 001134308.1_39522001_1 - 1.2e-16 60.0 3.7 1.2e-16 60.0 3.7 2.5 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001134308.1_39522001_1 - 5.6e-06 26.8 18.3 5.6e-06 26.8 18.3 2.5 2 0 0 2 2 2 1 Insulin-like growth factor binding protein ADAM_spacer1 PF05986.12 001133099.1_43529001_2 - 2.9e-32 111.0 0.1 5e-32 110.2 0.1 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.17 001133099.1_43529001_2 - 5.6e-23 81.6 0.0 5.7e-22 78.3 0.0 2.3 2 0 0 2 2 2 1 Reprolysin family propeptide TSP_1 PF00090.17 001133099.1_43529001_2 - 1.1e-19 70.2 37.9 3.5e-09 36.6 7.0 5.2 4 0 0 4 4 4 3 Thrombospondin type 1 domain Reprolysin PF01421.17 001133099.1_43529001_2 - 1.3e-19 70.8 0.1 2.1e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.4 001133099.1_43529001_2 - 2.8e-13 50.3 1.9 5.2e-13 49.5 1.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.4 001133099.1_43529001_2 - 3.4e-12 46.8 0.0 6.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.4 001133099.1_43529001_2 - 3.6e-05 23.4 0.2 5.7e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.4 001133099.1_43529001_2 - 5.8e-05 22.9 0.2 0.0001 22.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Insulin PF00049.16 001115096.1_37921001_1 - 1.4e-08 35.5 0.6 2.1e-08 34.9 0.6 1.3 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family PSD3 PF07626.9 001115096.1_37921001_1 - 0.17 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) Ins_beta PF03488.12 001115096.1_37921001_1 - 0.55 10.2 5.3 0.48 10.3 1.1 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Phosducin PF02114.14 001132397.1_43526001_2 - 7.9e-157 519.9 2.7 9.8e-157 519.6 2.7 1.1 1 0 0 1 1 1 1 Phosducin Actin PF00022.17 001134769.1_39724001_1 - 4.9e-128 427.1 0.0 1.1e-86 290.9 0.0 2.5 2 1 0 2 2 2 2 Actin Cytochrom_C PF00034.19 001134769.1_39724001_3 - 0.092 13.8 0.5 0.16 13.0 0.5 1.4 1 0 0 1 1 1 0 Cytochrome c BTB PF00651.29 001159716.1_43527001_2 - 4.9e-28 97.4 1.2 3.4e-14 52.9 0.0 3.8 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.20 001159716.1_43527001_2 - 4.2e-23 81.6 0.0 7.5e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001159716.1_43527001_2 - 2.1e-09 37.5 0.0 5.3e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IL7 PF01415.14 001032846.1_29622001_1 - 2.1e-47 160.4 3.4 2.5e-47 160.2 3.4 1.0 1 0 0 1 1 1 1 Interleukin 7/9 family Sulfate_transp PF00916.18 001184899.1_39525001_1 - 7.7e-115 383.5 22.5 1e-114 383.2 22.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001184899.1_39525001_1 - 2.5e-38 130.2 0.2 4.8e-38 129.3 0.2 1.5 1 0 0 1 1 1 1 STAS domain Tachykinin PF02202.14 001082596.1_39522001_2 - 7.4e-10 37.6 1.3 0.00084 18.9 1.0 2.4 2 0 0 2 2 2 2 Tachykinin family Defensin_propep PF00879.16 001082596.1_39522001_2 - 0.04 14.1 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Defensin propeptide I-set PF07679.14 001145181.1_39522001_3 - 1.3e-10 41.1 0.1 4.6e-10 39.3 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 001145181.1_39522001_3 - 2.6e-10 40.6 0.0 4.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.16 001145181.1_39522001_3 - 3.5e-09 37.0 24.0 3.5e-09 37.0 24.0 2.4 2 1 0 2 2 2 1 Insulin-like growth factor binding protein Kazal_2 PF07648.13 001145181.1_39522001_3 - 3e-08 33.6 1.2 7.8e-08 32.3 1.2 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.19 001145181.1_39522001_3 - 8.4e-07 28.8 0.2 2.1e-06 27.5 0.2 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain ig PF00047.23 001145181.1_39522001_3 - 5.2e-05 23.2 0.0 0.00012 22.1 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001145181.1_39522001_3 - 7.1e-05 23.0 0.0 0.00023 21.3 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 001145181.1_39522001_3 - 8.2e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Crystall PF00030.17 001173080.1_09922001_3 - 1.1e-60 201.6 1.0 1.1e-30 105.5 0.1 2.3 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.8 001173080.1_09922001_3 - 0.00077 19.5 0.4 3.1 7.9 0.1 3.0 3 0 0 3 3 3 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001173080.1_09922001_3 - 0.0018 18.0 0.9 0.14 12.0 0.3 2.9 2 2 0 2 2 2 1 Peptidase inhibitor family I36 SH2 PF00017.22 001190279.1_49828001_1 - 6.3e-16 58.1 0.0 2.2e-15 56.3 0.0 2.0 1 0 0 1 1 1 1 SH2 domain SAM_2 PF07647.15 001190279.1_49828001_1 - 6e-09 35.8 0.3 4.2e-08 33.0 0.0 2.6 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001190279.1_49828001_1 - 1.1e-08 35.3 0.2 3.3e-08 33.7 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Exo_endo_phos PF03372.21 001190279.1_49828001_1 - 1.7e-06 28.1 0.0 4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dysbindin PF04440.14 001098600.1_49823001_2 - 2.3e-64 215.8 1.5 5.2e-64 214.7 1.5 1.6 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) AIP3 PF03915.11 001098600.1_49823001_2 - 0.0036 16.3 12.4 0.0036 16.3 12.4 1.5 2 0 0 2 2 2 1 Actin interacting protein 3 DUF2730 PF10805.6 001098600.1_49823001_2 - 0.052 13.5 0.3 0.052 13.5 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Peptidase_S46 PF10459.7 001098600.1_49823001_2 - 0.1 11.1 6.6 0.13 10.7 6.6 1.1 1 0 0 1 1 1 0 Peptidase S46 Porin_3 PF01459.20 001126352.1_39522001_1 - 2.3e-82 276.4 3.9 2.5e-82 276.2 3.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin PH PF00169.27 001171383.1_37924001_1 - 5.3e-19 68.5 0.5 1.1e-18 67.5 0.5 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 001171383.1_37924001_1 - 1.3e-05 25.4 3.5 0.00011 22.5 3.5 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PhoU_div PF01865.14 001171383.1_37924001_1 - 0.0054 16.0 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF47 PH_2 PF08458.8 001171383.1_37924001_1 - 0.018 15.2 0.1 0.04 14.1 0.1 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Mcp5_PH PF12814.5 001171383.1_37924001_1 - 0.044 13.8 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.4 001171383.1_37924001_1 - 0.051 13.8 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.4 001171383.1_37924001_1 - 0.074 13.2 0.6 0.27 11.4 0.6 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.4 001171383.1_37924001_1 - 0.11 12.5 3.3 0.31 11.0 1.4 2.5 2 1 0 2 2 2 0 PH domain PMP22_Claudin PF00822.18 001110143.1_45723001_3 - 9.4e-20 71.0 1.8 9.4e-20 71.0 1.8 1.8 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001110143.1_45723001_3 - 2.1e-06 27.5 5.9 9.1e-06 25.4 5.9 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Thioredoxin PF00085.18 001163045.1_39524001_2 - 4e-68 225.8 0.1 1.8e-33 114.4 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.4 001163045.1_39524001_2 - 1.4e-35 122.8 1.7 4.1e-27 95.2 2.1 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.4 001163045.1_39524001_2 - 6.9e-09 36.0 1.1 0.00097 19.4 0.1 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001163045.1_39524001_2 - 4.7e-08 33.1 0.2 0.0025 18.0 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.4 001163045.1_39524001_2 - 3.9e-06 26.8 0.0 0.025 14.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.11 001163045.1_39524001_2 - 8.4e-06 25.2 0.0 0.056 12.6 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.19 001163045.1_39524001_2 - 7.5e-05 22.5 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Calsequestrin PF01216.15 001163045.1_39524001_2 - 0.00021 20.3 0.0 0.00046 19.2 0.0 1.5 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_4 PF13462.4 001163045.1_39524001_2 - 0.00031 20.8 0.3 0.31 11.0 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_3 PF13192.4 001163045.1_39524001_2 - 0.025 14.5 0.0 0.42 10.6 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain Ifi-6-16 PF06140.11 001048170.1_29622001_2 - 1.8e-18 66.0 21.4 4e-18 64.9 21.4 1.5 1 0 0 1 1 1 1 Interferon-induced 6-16 family Arfaptin PF06456.11 001162549.1_39523001_1 - 6.2e-81 271.2 3.7 7.3e-81 271.0 3.7 1.0 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.16 001162549.1_39523001_1 - 4.7e-06 26.3 6.4 7.6e-06 25.6 6.4 1.3 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.3 001162549.1_39523001_1 - 0.0081 15.7 5.2 0.015 14.9 5.2 1.4 1 0 0 1 1 1 1 BAR domain of APPL family TPR_MLP1_2 PF07926.10 001162549.1_39523001_1 - 0.85 9.6 4.7 1 9.3 0.7 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lipase PF00151.17 001142897.1_49824001_1 - 1.9e-156 520.4 0.0 2.3e-156 520.2 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.21 001142897.1_49824001_1 - 1.6e-14 54.3 0.7 6.9e-14 52.3 0.1 2.1 2 0 0 2 2 2 1 PLAT/LH2 domain Abhydrolase_6 PF12697.5 001142897.1_49824001_1 - 0.00023 21.7 0.0 0.00039 21.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.11 001142897.1_49824001_1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.10 001142897.1_49824001_1 - 0.03 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.18 001142897.1_49824001_1 - 0.054 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ank_2 PF12796.5 001082776.1_37925001_3 - 9e-32 109.4 9.7 7.5e-13 48.7 2.4 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ion_trans PF00520.29 001082776.1_37925001_3 - 7e-21 74.4 19.0 1.1e-20 73.8 19.0 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.4 001082776.1_37925001_3 - 6.5e-16 58.4 3.7 6.3e-06 26.5 0.3 4.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 001082776.1_37925001_3 - 9.4e-16 56.2 10.1 0.00013 22.0 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.28 001082776.1_37925001_3 - 2.2e-15 56.2 8.2 7.9e-05 22.8 0.1 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.4 001082776.1_37925001_3 - 1.1e-13 51.0 6.6 0.00014 22.0 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Mito_carr PF00153.25 001127271.1_39522001_1 - 1.4e-65 217.1 2.2 2.1e-23 81.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PDZ PF00595.22 213751.1_49825001_3 - 2.3e-23 82.2 0.5 6.6e-12 45.5 0.2 2.4 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 213751.1_49825001_3 - 1.9e-07 31.2 0.1 0.025 14.8 0.0 2.8 2 1 0 2 2 2 2 PDZ domain zf-C2H2 PF00096.24 001011505.1_49822001_1 - 1.1e-15 56.9 22.8 1.3e-05 25.3 3.3 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001011505.1_49822001_1 - 2.7e-13 49.6 8.9 2.1e-07 30.9 1.6 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001011505.1_49822001_1 - 3.7e-09 36.5 19.7 0.00043 20.7 1.6 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001011505.1_49822001_1 - 0.0024 18.0 9.5 1.9 8.8 0.3 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001011505.1_49822001_1 - 0.0034 17.6 16.2 0.13 12.6 0.6 4.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type FOXP-CC PF16159.3 001011505.1_49822001_1 - 0.0055 17.2 8.1 1.5 9.3 0.4 3.2 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.4 001011505.1_49822001_1 - 0.0092 15.8 0.7 0.0092 15.8 0.7 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001011505.1_49822001_1 - 0.034 14.3 7.0 0.066 13.4 7.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-Di19 PF05605.10 001011505.1_49822001_1 - 0.21 11.8 5.0 0.061 13.5 1.4 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.4 001011505.1_49822001_1 - 0.38 10.6 4.7 3.7 7.4 0.9 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_aberr PF17017.3 001011505.1_49822001_1 - 2.2 8.3 8.8 8.3 6.4 1.7 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger Sulfotransfer_1 PF00685.25 001082704.1_37925001_2 - 2e-58 197.9 0.0 2.6e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001082704.1_37925001_2 - 6.8e-10 39.6 0.1 4.6e-08 33.6 0.1 2.1 2 0 0 2 2 2 1 Sulfotransferase family FdsD PF11390.6 001082704.1_37925001_2 - 0.023 14.9 0.0 4.9 7.4 0.1 2.4 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Actin PF00022.17 001134354.1_49823001_1 - 6e-118 393.9 0.0 4.8e-117 390.9 0.0 1.9 1 1 0 1 1 1 1 Actin CaiF_GrlA PF07180.9 001099953.1_37924001_1 - 0.11 12.3 0.7 0.19 11.6 0.7 1.2 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator Pkinase PF00069.23 001099953.1_37924001_3 - 1e-74 251.1 0.0 1.7e-74 250.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.8 001099953.1_37924001_3 - 5.5e-60 201.0 0.0 9.4e-60 200.3 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.15 001099953.1_37924001_3 - 1.2e-34 119.6 0.0 2.6e-34 118.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase SnoaL_3 PF13474.4 001099953.1_37924001_3 - 6.8e-11 42.4 0.0 1.3e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.4 001099953.1_37924001_3 - 8.2e-10 38.9 0.0 1.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) APH PF01636.21 001099953.1_37924001_3 - 0.0035 17.2 0.1 0.88 9.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.12 001099953.1_37924001_3 - 0.006 15.8 0.1 0.014 14.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL_2 PF12680.5 001099953.1_37924001_3 - 0.03 14.8 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain FTA2 PF13095.4 001099953.1_37924001_3 - 0.081 12.4 0.1 5.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.20 001099953.1_37924001_3 - 0.099 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family OATP PF03137.18 001132870.1_43527001_3 - 9.5e-112 373.9 4.0 1.6e-111 373.2 4.0 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.14 001132870.1_43527001_3 - 2.3e-09 36.5 6.2 2.3e-09 36.5 6.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.13 001132870.1_43527001_3 - 0.014 15.4 3.8 0.032 14.3 3.8 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain LBP_BPI_CETP PF01273.23 001101032.1_49824001_3 - 9.6e-33 113.0 2.3 1.9e-32 112.0 2.3 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.15 001101032.1_49824001_3 - 1.3e-07 31.2 0.2 4.2e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain HAP PF03866.11 001101032.1_49824001_3 - 0.0043 17.0 2.4 0.0086 16.0 2.4 1.5 1 0 0 1 1 1 1 Hydrophobic abundant protein (HAP) Arf PF00025.19 001162550.1_39522001_1 - 4.1e-46 156.5 0.1 5.4e-46 156.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.20 001162550.1_39522001_1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001162550.1_39522001_1 - 3.2e-14 53.1 0.1 4.2e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.18 001162550.1_39522001_1 - 1.7e-10 40.5 0.1 1.5e-06 27.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.8 001162550.1_39522001_1 - 1.2e-09 37.8 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.10 001162550.1_39522001_1 - 1.9e-08 33.8 0.0 2.3e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001162550.1_39522001_1 - 6.5e-08 32.5 0.0 8.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thioredoxin PF00085.18 001195112.1_49824001_1 - 1.5e-68 227.1 0.0 1.2e-33 115.0 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.4 001195112.1_49824001_1 - 1.6e-36 125.8 0.8 9.5e-28 97.3 1.9 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.4 001195112.1_49824001_1 - 2.2e-09 37.6 0.6 0.00035 20.8 0.1 3.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001195112.1_49824001_1 - 8e-08 32.4 0.1 0.004 17.3 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.4 001195112.1_49824001_1 - 2.4e-06 27.5 0.0 0.018 15.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.19 001195112.1_49824001_1 - 3.5e-05 23.6 0.0 0.099 12.4 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.11 001195112.1_49824001_1 - 0.0001 21.7 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.4 001195112.1_49824001_1 - 0.00083 19.4 0.0 1.5 8.8 0.0 3.5 2 1 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.4 001195112.1_49824001_1 - 0.03 14.2 0.0 0.66 9.9 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain LRR_8 PF13855.4 001135059.1_39527001_1 - 1.3e-65 216.8 106.4 2.2e-09 36.8 7.2 14.5 9 4 4 14 14 14 13 Leucine rich repeat LRR_4 PF12799.5 001135059.1_39527001_1 - 3e-35 119.4 112.3 1.4e-07 31.5 3.6 16.1 9 5 8 18 18 18 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001135059.1_39527001_1 - 4.2e-13 49.2 27.2 0.00086 19.1 1.8 6.8 4 1 2 7 7 7 4 Leucine rich repeats (6 copies) TIR PF01582.18 001135059.1_39527001_1 - 2.6e-12 46.8 0.1 4.2e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001135059.1_39527001_1 - 3e-10 38.9 88.7 2.2 9.0 0.6 21.7 20 5 2 22 22 22 7 Leucine Rich Repeat LRR_9 PF14580.4 001135059.1_39527001_1 - 2.1e-07 30.5 45.8 0.0088 15.4 1.0 7.1 3 3 4 7 7 7 6 Leucine-rich repeat LRR_6 PF13516.4 001135059.1_39527001_1 - 0.00011 21.9 70.0 1.4 9.0 0.2 17.9 19 0 0 19 19 19 3 Leucine Rich repeat TIR_2 PF13676.4 001135059.1_39527001_1 - 0.00031 20.9 0.0 0.00061 19.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain RILP PF11461.6 001161873.1_39522001_2 - 1.8e-23 82.3 0.1 7.2e-23 80.4 0.1 2.1 1 0 0 1 1 1 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.7 001161873.1_39522001_2 - 0.00014 22.0 3.8 0.00031 20.9 3.8 1.7 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 EF-hand_2 PF09068.9 001127624.1_37626001_1 - 2.9e-37 127.4 0.1 7e-37 126.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.9 001127624.1_37626001_1 - 1.9e-34 117.8 0.1 8.1e-34 115.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand Spectrin PF00435.19 001127624.1_37626001_1 - 1.3e-10 41.5 7.7 5.4e-08 33.1 2.4 4.3 4 1 0 4 4 4 2 Spectrin repeat ZZ PF00569.15 001127624.1_37626001_1 - 1.3e-10 40.7 2.6 6.3e-10 38.6 3.0 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type WW PF00397.24 001127624.1_37626001_1 - 6.3e-08 32.3 1.2 1.3e-07 31.3 1.2 1.5 1 0 0 1 1 1 1 WW domain SOGA PF11365.6 001127624.1_37626001_1 - 0.035 15.1 10.3 0.64 11.1 0.6 3.6 3 1 1 4 4 4 0 Protein SOGA DUF4600 PF15372.4 001127624.1_37626001_1 - 0.21 11.9 7.4 1.7 8.9 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) bZIP_1 PF00170.19 001127624.1_37626001_1 - 0.38 10.7 9.0 0.38 10.8 1.9 3.6 3 0 0 3 3 3 0 bZIP transcription factor Nnf1 PF03980.12 001127624.1_37626001_1 - 2.2 8.5 17.5 0.75 10.1 2.2 4.1 4 1 0 4 4 4 0 Nnf1 HALZ PF02183.16 001127624.1_37626001_1 - 2.5 8.2 15.6 0.42 10.7 4.8 3.4 3 1 0 3 3 3 0 Homeobox associated leucine zipper LRR_8 PF13855.4 001130462.1_39726001_1 - 7.1e-64 211.3 55.3 1.9e-13 49.8 4.8 10.5 6 2 3 10 10 10 9 Leucine rich repeat TIR PF01582.18 001130462.1_39726001_1 - 3.2e-36 124.6 0.8 5e-36 124.0 0.8 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001130462.1_39726001_1 - 5.7e-28 96.3 58.7 0.0001 22.4 3.1 12.0 6 4 6 13 13 13 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001130462.1_39726001_1 - 5.6e-14 52.1 1.0 3.3e-07 30.2 0.1 4.5 3 2 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_1 PF00560.31 001130462.1_39726001_1 - 2.2e-11 42.4 45.4 0.71 10.4 0.1 15.7 15 2 0 15 15 15 4 Leucine Rich Repeat LRR_9 PF14580.4 001130462.1_39726001_1 - 2.2e-10 40.2 18.5 0.0041 16.5 0.9 5.8 2 2 4 6 6 6 5 Leucine-rich repeat TIR_2 PF13676.4 001130462.1_39726001_1 - 4.8e-06 26.7 0.0 9.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001130462.1_39726001_1 - 0.00037 20.2 45.0 9.4 6.4 0.0 14.3 15 0 0 15 15 15 2 Leucine Rich repeat LRRCT PF01463.22 001130462.1_39726001_1 - 0.0048 17.2 0.0 0.46 11.0 0.0 3.3 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain I-set PF07679.14 001168742.1_40424001_1 - 6.8e-33 112.5 0.0 3.6e-07 30.0 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.4 001168742.1_40424001_1 - 2.1e-32 111.4 0.0 4e-07 30.4 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.4 001168742.1_40424001_1 - 1.8e-21 76.1 0.0 1.6e-05 25.0 0.0 4.7 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.23 001168742.1_40424001_1 - 2.4e-21 75.6 0.1 1.3e-05 25.2 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin domain Izumo-Ig PF16706.3 001168742.1_40424001_1 - 1.2e-09 38.0 0.8 0.037 13.9 0.0 5.0 5 1 0 5 5 5 3 Izumo-like Immunoglobulin domain Ig_5 PF16681.3 001168742.1_40424001_1 - 2e-08 34.4 0.1 0.14 12.5 0.0 4.2 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.15 001168742.1_40424001_1 - 1.3e-06 28.4 0.4 2.1 8.4 0.2 5.2 4 2 1 5 5 5 2 Immunoglobulin V-set domain Ig_4 PF16680.3 001168742.1_40424001_1 - 1.8e-06 28.1 0.4 1.7 8.9 0.0 4.0 3 2 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain fn3 PF00041.19 001168742.1_40424001_1 - 0.0002 21.5 0.0 0.00055 20.1 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain BiPBP_C PF06832.10 001168742.1_40424001_1 - 0.00075 19.4 0.0 0.58 10.1 0.0 3.6 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Tissue_fac PF01108.15 001168742.1_40424001_1 - 0.029 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Tissue factor FAM194 PF14977.4 001168742.1_40424001_1 - 0.21 10.7 0.0 0.65 9.1 0.0 1.7 2 0 0 2 2 2 0 FAM194 protein OATP PF03137.18 001032941.1_29625001_3 - 2e-173 577.5 20.3 2.9e-173 576.9 20.3 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.14 001032941.1_29625001_3 - 5.9e-25 87.8 24.4 9e-19 67.5 5.7 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.13 001032941.1_29625001_3 - 8.4e-13 48.2 3.7 1.8e-12 47.1 3.7 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.19 001032941.1_29625001_3 - 0.00052 19.8 3.8 0.002 18.0 3.8 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.19 001132433.1_43528001_3 - 1.3e-79 267.1 4.5 1.9e-79 266.5 4.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001132433.1_43528001_3 - 1.2e-08 34.5 4.2 1.2e-08 34.5 4.2 2.4 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001132433.1_43528001_3 - 3e-06 27.0 6.6 1.8e-05 24.5 1.9 2.2 2 0 0 2 2 2 2 Olfactory receptor Sulfate_transp PF00916.18 001082098.1_37926001_1 - 3.6e-114 381.3 22.6 4.7e-114 381.0 22.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001082098.1_37926001_1 - 6.6e-39 132.0 0.1 1.4e-38 131.0 0.1 1.6 1 0 0 1 1 1 1 STAS domain Pkinase PF00069.23 001135931.1_39522001_1 - 1.4e-74 250.6 0.0 1.6e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001135931.1_39522001_1 - 5.5e-34 117.5 0.0 7e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001135931.1_39522001_1 - 0.0026 17.0 0.0 0.066 12.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.9 001135931.1_39522001_1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.21 001135931.1_39522001_1 - 0.038 13.8 0.0 0.086 12.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Atg8 PF02991.14 001190290.1_49824001_2 - 9.5e-42 141.3 0.2 1.4e-41 140.7 0.2 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.11 001190290.1_49824001_2 - 1.5e-05 25.2 0.1 4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 BAR_3 PF16746.3 001173097.1_09925001_1 - 3.2e-77 259.3 17.1 4.7e-77 258.7 17.1 1.3 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.25 001173097.1_09925001_1 - 4.8e-39 133.5 0.1 1.5e-38 131.9 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.27 001173097.1_09925001_1 - 2.8e-07 30.9 0.8 5.6e-07 29.9 0.1 1.9 2 0 0 2 2 2 1 PH domain Arfaptin PF06456.11 001173097.1_09925001_1 - 0.0045 16.5 1.5 0.013 15.0 1.5 1.8 1 0 0 1 1 1 1 Arfaptin-like domain DUF1073 PF06381.9 001173097.1_09925001_1 - 0.059 12.0 0.2 0.11 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) Patched PF02460.16 001173097.1_09925001_1 - 1.7 6.4 4.5 1.8 6.4 1.8 1.9 2 0 0 2 2 2 0 Patched family DUF3339 PF11820.6 001173097.1_09925001_2 - 0.069 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3339) HMG14_17 PF01101.16 022014.1_26224120_1 - 1.7e-17 64.0 21.0 2.6e-17 63.4 21.0 1.2 1 0 0 1 1 1 1 HMG14 and HMG17 7tm_4 PF13853.4 002169.1_26222120_2 - 2e-55 188.4 18.2 2.3e-55 188.1 18.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 002169.1_26222120_2 - 2e-19 69.8 22.5 6.2e-19 68.1 22.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UBA_5 PF16577.3 001266358.1_29624001_3 - 5.9e-43 144.7 0.1 1.5e-42 143.5 0.1 1.7 1 0 0 1 1 1 1 UBA domain ZZ PF00569.15 001266358.1_29624001_3 - 5.7e-12 45.1 3.5 1.2e-11 44.1 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.22 001266358.1_29624001_3 - 1.1e-11 44.3 0.0 1.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.14 001266358.1_29624001_3 - 0.0015 18.7 3.6 0.0034 17.5 3.6 1.6 1 0 0 1 1 1 1 C1 domain SRCR PF00530.16 001243468.1_49826001_2 - 2.7e-128 419.2 73.9 4.8e-30 103.9 7.5 5.2 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.4 001243468.1_49826001_2 - 1.7e-17 63.6 30.8 0.0019 18.5 1.8 5.5 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain Membr_traf_MHD PF10540.7 001243468.1_49826001_2 - 0.029 14.5 0.0 3.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain Tyrosinase PF00264.18 001285727.1_09024001_2 - 2.5e-35 122.7 0.3 4.6e-35 121.8 0.1 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Laminin_EGF PF00053.22 001285727.1_09024001_2 - 0.017 15.1 3.7 0.017 15.1 3.7 2.8 3 0 0 3 3 3 0 Laminin EGF domain RRM_1 PF00076.20 001260709.1_29627001_1 - 2.2e-32 110.6 0.1 1.7e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001260709.1_29627001_1 - 6e-17 61.4 0.1 2.9e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.4 001260709.1_29627001_1 - 0.00017 21.4 0.0 0.045 13.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif CBFNT PF08143.9 001260709.1_29627001_1 - 0.0037 18.5 1.1 0.0037 18.5 1.1 2.8 2 0 0 2 2 2 1 CBFNT (NUC161) domain RRM_3 PF08777.9 001260709.1_29627001_1 - 0.029 14.3 0.1 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif P21-Arc PF04062.12 001260766.1_29622001_3 - 1.5e-81 272.4 0.2 1.8e-81 272.1 0.2 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit zf-RanBP PF00641.16 001287723.1_29525001_2 - 7.2e-13 47.5 7.4 1.1e-12 46.9 7.4 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.20 001287723.1_29525001_2 - 1.7e-10 40.4 0.0 7e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ThiF PF00899.19 001283981.1_29525001_3 - 7e-48 163.0 0.1 1e-47 162.4 0.1 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.12 001283981.1_29525001_3 - 0.0074 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.16 001283981.1_29525001_3 - 0.038 14.1 0.5 0.87 9.7 0.5 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pox_A_type_inc PF04508.10 001283981.1_29525001_3 - 0.079 12.7 3.7 0.19 11.5 3.7 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DOR PF14839.4 001257771.1_29627001_3 - 1.8e-33 116.5 19.8 9.7e-33 114.0 16.1 2.7 1 1 1 2 2 2 1 DOR family Fructosamin_kin PF03881.12 001132895.2_43524001_1 - 2.7e-75 253.1 0.0 9.7e-75 251.3 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.21 001132895.2_43524001_1 - 1e-11 45.1 0.0 1.5e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.20 001132895.2_43524001_1 - 0.0036 16.8 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Death_2 PF14786.4 001132895.2_43524001_1 - 0.049 13.4 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Tube Death domain TIR_2 PF13676.4 001204457.1_37622001_1 - 2.4e-08 34.1 0.0 3.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001204457.1_37622001_1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 TIR domain F-box-like PF12937.5 001129739.1_39523001_1 - 4.5e-08 32.7 1.7 1e-07 31.6 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.31 001129739.1_39523001_1 - 2.7e-07 30.1 2.8 3.4e-07 29.8 0.2 2.6 3 0 0 3 3 3 1 F-box domain DUF4116 PF13475.4 001129739.1_39523001_1 - 0.0076 15.8 0.6 0.026 14.1 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4116) ANTH PF07651.14 001266499.1_29628001_1 - 4.7e-82 275.0 0.8 8.1e-82 274.2 0.8 1.4 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.18 001266499.1_29628001_1 - 4e-13 49.4 0.1 8.1e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 ENTH domain Herpes_PAP PF03325.11 001266499.1_29628001_1 - 3.3 6.6 4.5 7.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus polymerase accessory protein PI-PLC-X PF00388.17 001243589.1_49826001_3 - 5.3e-62 207.6 0.0 1.6e-61 206.0 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.17 001243589.1_49826001_3 - 1.5e-43 147.7 0.0 3.1e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.9 001243589.1_49826001_3 - 5.7e-37 126.0 1.9 3e-36 123.7 0.4 2.4 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.4 001243589.1_49826001_3 - 3.5e-26 90.7 3.3 6.5e-26 89.8 3.3 1.5 1 0 0 1 1 1 1 EF hand C2 PF00168.28 001243589.1_49826001_3 - 1.4e-18 67.0 0.2 3.1e-18 65.8 0.2 1.6 1 0 0 1 1 1 1 C2 domain PH PF00169.27 001243589.1_49826001_3 - 7.1e-06 26.4 1.0 1.5e-05 25.4 0.1 2.0 2 0 0 2 2 1 1 PH domain PH_12 PF16457.3 001243589.1_49826001_3 - 1.1e-05 25.8 0.0 2.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_6 PF13405.4 001243589.1_49826001_3 - 0.00017 21.2 0.4 0.068 13.0 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.30 001243589.1_49826001_3 - 0.00022 20.4 0.7 0.0047 16.2 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.4 001243589.1_49826001_3 - 0.00081 19.7 2.4 0.32 11.4 0.0 2.5 1 1 0 2 2 2 2 EF-hand domain pair TEP1_N PF05386.9 001243589.1_49826001_3 - 0.028 13.9 0.2 0.063 12.7 0.2 1.5 1 0 0 1 1 1 0 TEP1 N-terminal domain hSac2 PF12456.6 001244355.1_49823001_2 - 1.4e-27 95.5 0.0 2e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Inositol phosphatase OCD_Mu_crystall PF02423.13 001287652.1_29523001_2 - 7e-116 386.5 0.1 8.1e-116 386.3 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.18 001287652.1_29523001_2 - 2e-10 40.8 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.15 001287652.1_29523001_2 - 0.00014 22.3 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.13 001287652.1_29523001_2 - 0.0002 21.4 0.3 0.00047 20.2 0.3 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OTCace PF00185.22 001287652.1_29523001_2 - 0.052 13.5 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Metallothio PF00131.18 001252595.1_39721001_3 - 4.2e-19 68.3 64.6 5.4e-19 67.9 64.6 1.1 1 0 0 1 1 1 1 Metallothionein VWA_2 PF13519.4 001044535.1_49823001_2 - 1.9e-24 86.3 0.6 9.7e-24 84.0 0.0 2.5 4 1 0 4 4 4 1 von Willebrand factor type A domain VWA PF00092.26 001044535.1_49823001_2 - 1.9e-07 31.4 0.0 5.2e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.12 001044535.1_49823001_2 - 4.6e-07 29.7 0.1 7.7e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.18 001044535.1_49823001_2 - 4.7e-07 29.2 10.0 0.00012 21.6 0.4 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif TACI-CRD2 PF09305.8 001261540.1_29623001_2 - 0.79 9.7 5.0 0.2 11.6 1.0 2.1 2 0 0 2 2 2 0 TACI, cysteine-rich domain Synuclein PF01387.15 001261540.1_29623001_3 - 1.5e-48 164.2 10.2 3.7e-48 163.0 10.2 1.6 1 1 0 1 1 1 1 Synuclein Homeobox_KN PF05920.9 001244288.1_49824001_1 - 3e-17 62.1 0.9 6e-17 61.1 0.9 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.27 001244288.1_49824001_1 - 2.5e-07 30.3 1.2 4.9e-07 29.3 1.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.6 001244288.1_49824001_1 - 0.14 11.5 0.5 0.28 10.5 0.2 1.6 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Alpha-amylase_C PF02806.16 001266186.1_29624001_2 - 1.2e-15 57.6 0.2 2.8e-15 56.4 0.2 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.22 001266186.1_29624001_2 - 2.8e-13 50.0 0.0 5.4e-13 49.1 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3078 PF11276.6 001266186.1_29624001_2 - 0.026 14.8 0.1 0.069 13.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3078) V-set PF07686.15 001243504.1_49823001_1 - 0.0057 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 001243504.1_49823001_1 - 0.097 12.7 0.0 0.38 10.8 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin domain EGF_CA PF07645.13 001266467.1_29625001_3 - 4.9e-12 45.7 29.2 4.8e-08 32.9 10.0 5.8 4 2 0 5 5 5 2 Calcium-binding EGF domain DUF3456 PF11938.6 001266467.1_29625001_3 - 9.5e-11 42.3 1.3 1.6e-05 25.3 0.0 2.3 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP EGF PF00008.25 001266467.1_29625001_3 - 0.0054 16.9 2.1 0.0054 16.9 2.1 5.9 5 0 0 5 5 5 1 EGF-like domain cEGF PF12662.5 001266467.1_29625001_3 - 0.022 14.5 0.7 0.022 14.5 0.7 5.2 5 0 0 5 5 5 0 Complement Clr-like EGF-like EGF_3 PF12947.5 001266467.1_29625001_3 - 0.024 14.7 2.8 0.024 14.7 2.8 4.6 4 0 0 4 4 4 0 EGF domain hEGF PF12661.5 001266467.1_29625001_3 - 0.031 14.8 5.4 0.031 14.8 5.4 6.7 8 0 0 8 8 8 0 Human growth factor-like EGF IL1 PF00340.17 001257238.1_09922001_1 - 2.8e-29 101.1 0.2 4.3e-29 100.5 0.2 1.3 1 0 0 1 1 1 1 Interleukin-1 / 18 LBP_BPI_CETP PF01273.23 001243255.1_49822001_3 - 3.7e-27 94.8 0.1 5.2e-27 94.3 0.1 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain bZIP_1 PF00170.19 001265999.1_29626001_1 - 6e-13 48.6 11.9 1.2e-12 47.6 11.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001265999.1_29626001_1 - 3.9e-09 36.3 9.7 1.1e-08 34.8 9.7 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001265999.1_29626001_1 - 7.7e-05 23.0 10.5 0.00016 22.0 10.5 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.10 001265999.1_29626001_1 - 0.002 18.4 2.6 0.0051 17.1 2.6 1.6 1 0 0 1 1 1 1 Cell division protein ZapB IncA PF04156.12 001265999.1_29626001_1 - 0.061 13.0 4.6 0.11 12.1 4.6 1.4 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.4 001265999.1_29626001_1 - 0.1 11.8 0.8 0.16 11.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.4 001265999.1_29626001_1 - 0.6 9.4 5.8 0.96 8.8 5.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.4 001265999.1_29626001_1 - 0.63 9.7 8.9 1 9.0 8.9 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH JMY PF15871.3 001265999.1_29626001_1 - 0.82 8.8 3.9 1.2 8.2 3.9 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein APG6 PF04111.10 001265999.1_29626001_1 - 0.83 8.9 4.5 1.3 8.2 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Jnk-SapK_ap_N PF09744.7 001265999.1_29626001_1 - 1.3 9.1 8.4 2.2 8.3 8.4 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.6 001265999.1_29626001_1 - 3.4 7.6 14.4 5.9 6.8 14.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.12 001265999.1_29626001_1 - 4.7 6.8 6.2 8.2 6.1 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BAG PF02179.14 001266057.2_29625001_1 - 4.3e-18 65.4 4.1 6.5e-18 64.8 4.1 1.3 1 0 0 1 1 1 1 BAG domain WW PF00397.24 001266057.2_29625001_1 - 2.7e-10 39.9 1.7 6.4e-10 38.7 1.7 1.7 1 0 0 1 1 1 1 WW domain PITH PF06201.11 001244276.1_49823001_1 - 1.4e-40 138.8 0.1 1.9e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.18 001244276.1_49823001_1 - 6.3e-17 61.3 0.0 1.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.11 001244276.1_49823001_1 - 0.003 16.8 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Plexin_cytopl PF08337.10 001261691.1_29629001_1 - 2.2e-200 666.9 11.5 1.2e-197 657.8 11.5 2.1 1 1 0 1 1 1 1 Plexin cytoplasmic RasGAP domain PSI PF01437.23 001261691.1_29629001_1 - 1.6e-14 54.0 37.4 1.5e-10 41.3 14.1 3.4 3 0 0 3 3 3 2 Plexin repeat TIG PF01833.22 001261691.1_29629001_1 - 4.2e-12 45.9 11.2 5.5e-06 26.2 0.2 3.6 3 0 0 3 3 3 2 IPT/TIG domain Sema PF01403.17 001261691.1_29629001_1 - 3.1e-10 39.3 0.4 3.4e-08 32.5 0.0 2.9 2 1 0 2 2 2 1 Sema domain PSI_integrin PF17205.1 001261691.1_29629001_1 - 0.0034 17.1 11.9 0.0034 17.1 11.9 2.9 2 0 0 2 2 2 1 Integrin plexin domain Cystatin PF00031.19 001244639.1_49824001_2 - 5e-11 42.6 0.0 5.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.15 001244639.1_49824001_2 - 0.00021 21.4 0.1 0.001 19.2 0.0 1.9 2 0 0 2 2 2 1 Cathelicidin RabGAP-TBC PF00566.16 001244620.1_49826001_3 - 8.9e-29 100.5 0.1 1.7e-28 99.7 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phospholip_A2_1 PF00068.17 001244874.1_49826001_3 - 5.3e-33 113.6 13.1 9.1e-33 112.9 13.1 1.3 1 0 0 1 1 1 1 Phospholipase A2 MBD PF01429.17 001257542.1_29629001_3 - 4.6e-16 58.1 0.0 9e-16 57.2 0.0 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain PIG-P PF08510.10 001243521.1_49822001_2 - 5.5e-41 139.2 2.7 7e-41 138.8 2.7 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.10 001243521.1_49822001_2 - 0.00045 20.3 6.2 0.00086 19.4 6.2 1.4 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Phage_holin_3_6 PF07332.9 001243521.1_49822001_2 - 0.04 13.8 0.2 0.06 13.3 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Inj_translocase PF16928.3 001243521.1_49822001_2 - 0.2 10.9 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome DUF3261 PF11659.6 001243521.1_49822001_2 - 0.65 9.8 2.5 0.36 10.6 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3261) RRM_1 PF00076.20 001132962.1_43529001_3 - 2.7e-75 248.0 0.4 5.8e-21 74.0 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001132962.1_43529001_3 - 5.3e-11 42.1 0.0 0.0019 17.6 0.0 3.5 2 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001132962.1_43529001_3 - 1.2e-07 31.3 0.0 0.00072 19.2 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.3 001132962.1_43529001_3 - 0.0025 17.8 0.0 3.6 7.6 0.0 4.0 4 0 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.9 001132962.1_43529001_3 - 0.0031 17.4 0.5 0.27 11.1 0.1 2.4 2 0 0 2 2 2 1 RNA binding motif TC1 PF15063.4 001132962.1_43529001_3 - 0.0033 17.1 0.0 0.033 13.9 0.0 2.3 2 0 0 2 2 2 1 Thyroid cancer protein 1 Nup35_RRM_2 PF14605.4 001132962.1_43529001_3 - 0.16 11.8 1.6 48 3.9 0.0 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif PIG-P PF08510.10 001243520.1_49822001_1 - 1.3e-40 137.9 2.7 1.7e-40 137.6 2.7 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.10 001243520.1_49822001_1 - 0.00097 19.3 6.2 0.0017 18.5 6.2 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Phage_holin_3_6 PF07332.9 001243520.1_49822001_1 - 0.095 12.6 0.4 0.15 12.0 0.4 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Ion_trans PF00520.29 001244280.2_49824001_2 - 3.3e-31 108.2 28.6 4.2e-31 107.9 28.6 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.10 001244280.2_49824001_2 - 0.098 11.2 21.1 0.0061 15.2 12.4 2.1 1 1 1 2 2 2 0 Polycystin cation channel TPT PF03151.14 001266345.1_29625001_3 - 1e-91 307.2 13.4 1e-91 307.2 13.4 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.18 001266345.1_29625001_3 - 6.6e-12 45.6 24.6 4.2e-07 30.1 12.9 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.9 001266345.1_29625001_3 - 8.2e-05 21.8 16.6 0.00012 21.3 16.6 1.2 1 0 0 1 1 1 1 UAA transporter family TMEM234 PF10639.7 001266345.1_29625001_3 - 0.059 13.3 6.3 1.1 9.2 0.3 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 LRR_8 PF13855.4 001285699.1_09026001_1 - 1.3e-59 197.7 62.6 8.3e-14 51.0 4.3 11.5 6 4 5 11 11 11 10 Leucine rich repeat TIR PF01582.18 001285699.1_09026001_1 - 5.5e-31 107.6 0.6 8.7e-31 106.9 0.6 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001285699.1_09026001_1 - 2.7e-19 68.7 66.8 4.8e-05 23.5 3.6 11.3 5 2 9 14 14 14 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001285699.1_09026001_1 - 4.9e-13 49.0 3.2 1.7e-07 31.1 0.3 4.6 5 1 1 6 6 6 3 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001285699.1_09026001_1 - 3.4e-07 29.8 17.9 0.057 12.8 1.2 5.6 2 2 3 5 5 5 3 Leucine-rich repeat TIR_2 PF13676.4 001285699.1_09026001_1 - 2.8e-06 27.4 0.1 6.2e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001285699.1_09026001_1 - 5.1e-05 22.9 39.1 1.5 8.9 0.2 12.8 15 0 0 15 15 15 3 Leucine Rich repeat LRR_1 PF00560.31 001285699.1_09026001_1 - 0.00014 21.7 50.6 1.4 9.6 0.4 14.4 14 3 0 14 14 14 3 Leucine Rich Repeat Pkinase_Tyr PF07714.15 001267878.1_39524001_2 - 1.4e-38 132.5 0.0 2.2e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.4 001267878.1_39524001_2 - 1.9e-22 78.8 1.2 3.2e-10 40.0 0.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.23 001267878.1_39524001_2 - 4.3e-22 78.6 0.0 7.2e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.5 001267878.1_39524001_2 - 2.3e-19 69.6 0.1 1.4e-10 41.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001267878.1_39524001_2 - 4.9e-18 64.6 0.2 1.3e-05 25.3 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.4 001267878.1_39524001_2 - 2.6e-17 62.8 3.1 4.9e-08 33.2 0.1 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.4 001267878.1_39524001_2 - 7.2e-16 56.6 0.1 5.1e-05 23.2 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Sulfate_transp PF00916.18 001246664.1_09924001_3 - 4.8e-94 315.1 18.2 6.2e-94 314.7 18.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001246664.1_09924001_3 - 1.1e-10 41.0 0.0 1.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.4 001246664.1_09924001_3 - 0.00043 20.4 1.0 0.00092 19.4 1.0 1.6 1 0 0 1 1 1 1 STAS domain Ank_2 PF12796.5 001266289.2_29625001_1 - 8.8e-40 135.1 0.0 6.3e-14 52.2 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001266289.2_29625001_1 - 4.5e-38 129.0 5.1 4.4e-10 39.7 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.28 001266289.2_29625001_1 - 8.3e-35 117.6 0.4 8.4e-06 25.9 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.4 001266289.2_29625001_1 - 9.8e-32 108.4 5.9 4.7e-06 26.7 0.2 6.7 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.4 001266289.2_29625001_1 - 4.9e-27 90.9 2.9 0.00011 22.2 0.0 8.2 7 1 0 7 7 7 6 Ankyrin repeat SOCS_box PF07525.14 001266289.2_29625001_1 - 7.2e-08 32.5 1.9 7.2e-08 32.5 1.9 2.1 2 0 0 2 2 2 1 SOCS box Cys_knot PF00007.20 001079832.1_39721001_2 - 3.8e-32 110.6 6.5 4.5e-32 110.4 6.5 1.1 1 0 0 1 1 1 1 Cystine-knot domain Bcl-2 PF00452.17 001009226.2_39522001_2 - 1.6e-34 118.3 0.1 2.8e-34 117.6 0.1 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.15 001009226.2_39522001_2 - 1.6e-14 53.2 0.3 2.8e-14 52.4 0.3 1.4 1 0 0 1 1 1 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.4 001009226.2_39522001_2 - 0.017 15.7 0.0 0.024 15.2 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like PRY PF13765.4 001128479.1_49823001_1 - 8.1e-22 76.5 0.5 1.9e-21 75.2 0.5 1.7 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.26 001128479.1_49823001_1 - 2.7e-21 75.8 0.1 7e-21 74.4 0.0 1.7 2 0 0 2 2 1 1 SPRY domain zf-C3HC4_4 PF15227.4 001128479.1_49823001_1 - 3.5e-15 55.7 8.4 3.5e-15 55.7 8.4 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.23 001128479.1_49823001_1 - 1.5e-12 47.1 6.5 1.5e-12 47.1 6.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001128479.1_49823001_1 - 1.1e-10 41.0 7.1 1.1e-10 41.0 7.1 2.5 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001128479.1_49823001_1 - 5.8e-10 38.9 5.9 5.8e-10 38.9 5.9 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.4 001128479.1_49823001_1 - 1.5e-09 37.4 5.4 1.5e-09 37.4 5.4 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001128479.1_49823001_1 - 1.3e-08 34.8 8.7 1.3e-08 34.8 8.7 2.6 3 0 0 3 3 2 1 Ring finger domain zf-B_box PF00643.22 001128479.1_49823001_1 - 2.7e-08 33.7 4.3 2.7e-08 33.7 4.3 2.8 4 0 0 4 4 2 1 B-box zinc finger zf-RING_5 PF14634.4 001128479.1_49823001_1 - 3.2e-07 30.0 5.4 3.2e-07 30.0 5.4 2.7 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_6 PF14835.4 001128479.1_49823001_1 - 5.5e-07 29.2 1.8 1.4e-06 28.0 1.8 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.4 001128479.1_49823001_1 - 1.2e-05 24.9 5.5 1.2e-05 24.9 5.5 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.5 001128479.1_49823001_1 - 3.3e-05 23.9 4.5 3.3e-05 23.9 4.5 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.3 001128479.1_49823001_1 - 8.8e-05 22.4 2.8 8.8e-05 22.4 2.8 2.4 3 0 0 3 3 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.5 001128479.1_49823001_1 - 0.00061 19.7 0.9 0.00061 19.7 0.9 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.9 001128479.1_49823001_1 - 0.011 15.6 2.2 0.047 13.5 2.2 2.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) U-box PF04564.13 001128479.1_49823001_1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 U-box domain Exonuc_VII_L PF02601.13 001128479.1_49823001_1 - 0.012 15.1 6.8 0.017 14.6 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-Nse PF11789.6 001128479.1_49823001_1 - 0.03 14.0 2.2 0.081 12.6 2.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Fmp27_WPPW PF10359.7 001128479.1_49823001_1 - 0.044 12.5 7.9 0.062 12.0 7.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Amidase_2 PF01510.23 001128479.1_49823001_1 - 0.099 13.0 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DUF2408 PF10303.7 001128479.1_49823001_1 - 0.33 11.4 11.2 1.2 9.6 11.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Fib_alpha PF08702.8 001128479.1_49823001_1 - 0.45 10.6 8.1 0.49 10.4 7.0 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family OmpH PF03938.12 001128479.1_49823001_1 - 0.63 9.9 7.9 1.6 8.6 7.9 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prim_Zn_Ribbon PF08273.10 001128479.1_49823001_1 - 0.71 10.2 3.3 2.3 8.5 0.2 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-C3HC4_5 PF17121.3 001128479.1_49823001_1 - 0.77 9.6 6.1 3.8 7.3 5.0 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FUSC PF04632.10 001128479.1_49823001_1 - 1 7.7 1.9 1.4 7.3 1.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_C101 PF16218.3 001128479.1_49823001_1 - 1.3 8.1 5.6 0.4 9.8 1.0 2.1 1 1 1 2 2 2 0 Peptidase family C101 Apolipoprotein PF01442.16 001128479.1_49823001_1 - 1.4 8.7 17.3 0.41 10.4 13.6 2.0 2 1 0 2 2 1 0 Apolipoprotein A1/A4/E domain 4HB_MCP_1 PF12729.5 001128479.1_49823001_1 - 1.8 7.9 4.1 3.4 7.1 1.3 2.3 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction TMCO5 PF14992.4 001128479.1_49823001_1 - 1.9 7.8 16.6 3.1 7.2 15.9 1.6 1 1 0 1 1 1 0 TMCO5 family HAUS6_N PF14661.4 001128479.1_49823001_1 - 3.2 7.2 10.1 0.84 9.1 2.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF342 PF03961.11 001128479.1_49823001_1 - 3.8 5.9 9.8 2.9 6.3 8.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF1043 PF06295.10 001128479.1_49823001_1 - 4.4 7.2 6.6 3.8 7.4 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Pro_CA PF00484.17 001128479.1_49823001_1 - 5.2 7.2 6.9 2.4 8.3 0.3 2.5 1 1 0 2 2 2 0 Carbonic anhydrase zf-RING_UBOX PF13445.4 001244691.1_49824001_1 - 5.9e-10 38.9 3.9 1.8e-09 37.3 3.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.4 001244691.1_49824001_1 - 2.9e-08 33.3 2.3 2.9e-08 33.3 2.3 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001244691.1_49824001_1 - 5.2e-08 32.5 3.2 5.2e-08 32.5 3.2 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.22 001244691.1_49824001_1 - 5.3e-07 29.6 6.5 5.3e-07 29.6 6.5 3.8 4 0 0 4 4 4 1 B-box zinc finger zf-RING_2 PF13639.4 001244691.1_49824001_1 - 5.7e-07 29.6 4.6 5.7e-07 29.6 4.6 2.9 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.4 001244691.1_49824001_1 - 1.5e-06 28.0 4.7 1.5e-06 28.0 4.7 2.6 3 0 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001244691.1_49824001_1 - 1.2e-05 24.9 7.0 1.2e-05 24.9 7.0 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.4 001244691.1_49824001_1 - 2.9e-05 24.0 7.0 2.9e-05 24.0 7.0 3.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.4 001244691.1_49824001_1 - 3.1e-05 23.6 0.4 3.1e-05 23.6 0.4 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF1076 PF06416.10 001244691.1_49824001_1 - 0.026 14.3 0.6 0.26 11.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1076) NABP PF07990.10 001244691.1_49824001_1 - 0.089 12.1 0.3 0.16 11.3 0.3 1.3 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Cbl_N PF02262.14 001244691.1_49824001_1 - 0.2 11.6 2.0 0.46 10.4 0.4 2.1 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 DUF1664 PF07889.10 001244691.1_49824001_1 - 0.63 9.9 3.0 1.1 9.1 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_11 PF17123.3 001244691.1_49824001_1 - 2.3 7.9 9.8 2 8.1 6.2 2.6 2 0 0 2 2 2 0 RING-like zinc finger NT-C2 PF10358.7 001261603.1_29624001_2 - 7.2e-29 100.3 0.0 1.6e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins EamA PF00892.18 001260796.1_29623001_1 - 2.9e-19 69.5 31.4 3.3e-10 40.1 7.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family MatE PF01554.16 001131190.2_43527001_1 - 1.8e-61 206.4 27.2 7.1e-31 106.9 9.0 2.5 2 0 0 2 2 2 2 MatE Mito_carr PF00153.25 001258408.1_49823001_2 - 1.5e-33 114.4 0.1 9.2e-11 41.4 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Bac_export_1 PF01311.18 001258408.1_49823001_2 - 0.083 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial export proteins, family 1 Aldedh PF00171.20 001252213.1_49827001_2 - 2e-100 336.4 0.0 2.5e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family XAP5 PF04921.12 001267791.1_29624001_3 - 4.6e-78 262.2 16.4 1.4e-77 260.7 16.4 1.8 1 1 0 1 1 1 1 XAP5, circadian clock regulator PP2C PF00481.19 001257613.2_29625001_1 - 2.3e-74 250.2 0.4 5.3e-57 193.3 0.6 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.4 001257613.2_29625001_1 - 0.016 14.7 0.0 0.047 13.2 0.0 1.8 2 1 0 2 2 2 0 Protein phosphatase 2C ArgoL1 PF08699.8 001257613.2_29625001_1 - 0.14 11.6 1.1 0.52 9.9 0.2 2.3 3 0 0 3 3 3 0 Argonaute linker 1 domain Presenilin PF01080.15 001257613.2_29625001_1 - 9.1 4.8 7.1 14 4.2 7.1 1.3 1 0 0 1 1 1 0 Presenilin OATP PF03137.18 001261711.1_29629001_3 - 1.9e-172 574.2 23.8 2.3e-172 573.9 23.8 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.14 001261711.1_29629001_3 - 5e-24 84.8 4.8 5e-24 84.8 4.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.13 001261711.1_29629001_3 - 8.7e-09 35.3 1.6 8.7e-09 35.3 1.6 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.19 001261711.1_29629001_3 - 0.0021 17.9 4.8 0.0061 16.4 4.8 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain TGFb_propeptide PF00688.16 001257475.1_29625001_1 - 2.9e-35 122.1 0.1 3.7e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 001257475.1_29625001_1 - 6.1e-24 84.8 1.3 1.1e-23 83.9 1.3 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain Trypsin PF00089.24 001261097.1_29623001_1 - 3.3e-68 229.7 0.4 4.1e-68 229.4 0.4 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001261097.1_29623001_1 - 2.8e-06 28.1 0.0 5.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001261097.1_29623001_1 - 0.0059 16.9 0.1 0.02 15.2 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) MFS_1 PF07690.14 001243471.1_49825001_3 - 1.5e-13 50.3 29.2 2.4e-13 49.6 29.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Yip1 PF04893.15 001260957.1_29623001_2 - 2.2e-09 37.1 16.2 3.1e-09 36.6 16.2 1.2 1 0 0 1 1 1 1 Yip1 domain EF-hand_7 PF13499.4 001266371.1_29624001_1 - 1.5e-15 57.3 2.0 4e-11 43.1 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001266371.1_29624001_1 - 2.5e-14 51.5 2.2 9e-06 24.8 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.4 001266371.1_29624001_1 - 4.8e-14 50.9 1.2 6.8e-06 25.5 0.2 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.4 001266371.1_29624001_1 - 4.2e-07 29.5 1.0 0.00019 21.0 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.4 001266371.1_29624001_1 - 1.4e-05 24.3 3.4 0.069 12.6 0.1 3.4 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.7 001266371.1_29624001_1 - 0.00062 19.9 0.0 0.024 14.8 0.0 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.6 001266371.1_29624001_1 - 0.002 17.9 0.1 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain Interferon PF00143.17 001089303.1_22422001_1 - 1.8e-54 184.1 0.0 2e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Trypsin PF00089.24 001243690.1_49826001_2 - 3.7e-64 216.4 0.2 5.5e-64 215.9 0.2 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.16 001243690.1_49826001_2 - 1.8e-21 76.1 3.9 1.8e-21 76.1 3.9 2.5 2 0 0 2 2 2 1 Kringle domain EGF PF00008.25 001243690.1_49826001_2 - 1.6e-11 44.1 45.0 1.4e-06 28.3 7.1 4.6 4 0 0 4 4 4 3 EGF-like domain DUF1986 PF09342.9 001243690.1_49826001_2 - 0.0019 18.5 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) EGF_2 PF07974.11 001243690.1_49826001_2 - 0.21 11.8 41.5 0.57 10.5 10.7 4.2 3 0 0 3 3 3 0 EGF-like domain Plasmod_Pvs28 PF06247.9 001243690.1_49826001_2 - 0.72 10.1 20.1 0.26 11.5 9.8 3.3 2 1 0 2 2 2 0 Pvs28 EGF domain Atg8 PF02991.14 001246576.1_39725001_1 - 3.2e-42 142.8 0.2 4.8e-42 142.2 0.2 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.11 001246576.1_39725001_1 - 1.7e-05 25.0 0.0 3.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Interferon PF00143.17 001245020.1_22422001_1 - 1.7e-57 193.9 0.2 2e-57 193.7 0.2 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain RRM_1 PF00076.20 001260865.1_29623001_3 - 7.3e-16 57.6 0.0 1.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tetraspannin PF00335.18 001266877.1_29625001_1 - 2.5e-44 151.5 12.3 3.6e-44 151.0 12.3 1.2 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.10 001266877.1_29625001_1 - 0.92 9.0 11.9 0.68 9.4 5.8 2.4 2 0 0 2 2 2 0 SUR7/PalI family DUF3524 PF12038.6 001261488.2_29626001_2 - 7.3e-70 234.0 0.0 1e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.18 001261488.2_29626001_2 - 1.8e-07 30.8 0.0 3.9e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Mito_carr PF00153.25 001266009.2_29623001_2 - 4.2e-18 64.9 0.0 1e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Robl_LC7 PF03259.15 001190180.1_49822001_1 - 1.4e-25 88.8 0.0 1.7e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.3 001190180.1_49822001_1 - 0.0016 18.2 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 TACC PF05010.12 001258352.1_49828001_1 - 1.3e-84 282.8 33.7 2.1e-84 282.2 33.7 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Skp1_POZ PF03931.13 001258352.1_49828001_1 - 0.016 15.2 0.4 0.046 13.8 0.4 1.8 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain NRIP1_repr_3 PF15689.3 001258352.1_49828001_1 - 0.095 12.9 0.1 0.095 12.9 0.1 3.6 3 0 0 3 3 3 0 Nuclear receptor-interacting protein 1 repression 3 Adap_comp_sub PF00928.19 001243917.1_49825001_3 - 1.2e-91 306.6 0.6 1.2e-91 306.6 0.6 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.18 001243917.1_49825001_3 - 0.00013 21.8 0.9 0.00021 21.1 0.9 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pyr_redox_3 PF13738.4 001244741.1_49826001_1 - 9e-33 113.7 0.0 7.3e-32 110.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.12 001244741.1_49826001_1 - 6.8e-10 38.5 0.0 1.2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.4 001244741.1_49826001_1 - 3.9e-07 30.1 0.0 1.4e-06 28.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.12 001244741.1_49826001_1 - 1.1e-06 27.5 0.0 2.4e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 HI0933-like protein DAO PF01266.22 001244741.1_49826001_1 - 8e-06 25.6 0.0 0.0061 16.1 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.25 001244741.1_49826001_1 - 1.2e-05 25.6 0.0 0.012 16.0 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.4 001244741.1_49826001_1 - 6.5e-05 22.1 0.0 0.00018 20.6 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.17 001244741.1_49826001_1 - 0.00054 18.4 0.0 0.0008 17.8 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.17 001244741.1_49826001_1 - 0.0037 16.5 0.0 0.022 13.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.22 001244741.1_49826001_1 - 0.047 12.8 0.0 0.83 8.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.15 001244741.1_49826001_1 - 0.075 12.1 0.0 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Thi4 family 7tm_1 PF00001.19 001285636.1_09025001_1 - 3.2e-32 111.7 22.9 4.9e-32 111.1 22.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GnHR_trans PF12369.6 001285636.1_09025001_1 - 2.7e-26 92.0 0.9 5.7e-26 91.0 0.9 1.5 1 0 0 1 1 1 1 Gonadotropin hormone receptor transmembrane region LRR_8 PF13855.4 001285636.1_09025001_1 - 5.3e-21 74.0 10.3 5e-06 26.1 0.0 5.2 3 2 2 5 5 5 4 Leucine rich repeat LRR_5 PF13306.4 001285636.1_09025001_1 - 5.7e-14 52.1 0.2 3.7e-07 30.0 0.0 2.4 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRRNT PF01462.16 001285636.1_09025001_1 - 5e-06 25.9 2.7 5e-06 25.9 2.7 2.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001285636.1_09025001_1 - 6.8e-06 26.2 15.5 0.81 10.0 0.1 4.9 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001285636.1_09025001_1 - 0.0032 16.9 0.8 0.031 13.6 0.5 2.4 2 0 0 2 2 2 1 Leucine-rich repeat Sigma70_r4 PF04545.14 001285636.1_09025001_1 - 0.16 11.4 0.0 0.4 10.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 LRR_1 PF00560.31 001285636.1_09025001_1 - 1 10.0 9.2 33 5.4 0.2 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat Sulfate_transp PF00916.18 001246663.1_09925001_2 - 2.6e-114 381.8 21.1 3.5e-114 381.4 21.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001246663.1_09925001_2 - 3.8e-23 81.2 0.0 7.4e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.3 001246663.1_09925001_2 - 0.009 16.1 2.8 0.009 16.1 2.8 3.6 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily Gaa1 PF04114.12 001246663.1_09925001_2 - 1.8 7.4 14.2 0.08 11.9 5.6 2.1 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component RhoGAP PF00620.25 001260948.1_29629001_2 - 4.5e-36 123.8 1.0 1.7e-35 121.9 0.0 2.4 3 0 0 3 3 3 1 RhoGAP domain Drc1-Sld2 PF11719.6 001260948.1_29629001_2 - 0.0012 18.3 3.8 0.0012 18.3 3.8 3.9 2 1 2 4 4 4 2 DNA replication and checkpoint protein PilJ PF13675.4 001260948.1_29629001_2 - 0.099 12.6 4.6 1.2 9.1 1.3 2.6 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term GST_N_3 PF13417.4 001132263.2_43528001_3 - 3.7e-15 55.9 0.0 6.5e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001132263.2_43528001_3 - 9.3e-12 45.0 0.0 1.7e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001132263.2_43528001_3 - 6.5e-10 38.7 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001132263.2_43528001_3 - 1.4e-08 34.8 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001132263.2_43528001_3 - 6.1e-07 29.4 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001132263.2_43528001_3 - 2.7e-06 27.3 0.2 7.3e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.7 001132263.2_43528001_3 - 0.1 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein PXA PF02194.13 001257900.1_29627001_1 - 1e-36 126.2 1.9 2.5e-36 124.9 1.4 2.0 2 0 0 2 2 2 1 PXA domain PX PF00787.22 001257900.1_29627001_1 - 2.7e-20 72.3 1.9 2.7e-20 72.3 1.9 2.9 3 0 0 3 3 3 1 PX domain Nexin_C PF08628.10 001257900.1_29627001_1 - 5.9e-16 58.9 0.0 1.9e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Sorting nexin C terminal RGS PF00615.17 001257900.1_29627001_1 - 1.4e-11 44.5 2.4 1.4e-11 44.5 2.4 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain CSD PF00313.20 001173041.1_09923001_2 - 4.3e-26 90.4 0.5 7e-26 89.7 0.5 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.9 001173041.1_09923001_2 - 0.019 14.5 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain EF-hand_7 PF13499.4 001265791.1_29625001_2 - 2.9e-07 30.7 1.5 5.3e-07 29.9 1.5 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.30 001265791.1_29625001_2 - 1.5e-06 27.2 9.5 0.0002 20.5 2.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.4 001265791.1_29625001_2 - 1.6e-06 27.4 1.7 0.00015 21.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.4 001265791.1_29625001_2 - 0.0042 16.4 0.2 0.0042 16.4 0.2 2.3 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.7 001265791.1_29625001_2 - 0.044 14.0 0.0 0.044 14.0 0.0 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.4 001265791.1_29625001_2 - 3.1 7.5 6.6 11 5.8 1.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair Trm112p PF03966.14 001271967.1_49823001_1 - 1.6e-07 31.6 0.0 3.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Trm112p-like protein PIG-Y PF15159.4 001271967.1_49823001_3 - 5.7e-17 62.1 2.2 1.1e-16 61.2 2.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y LRR_8 PF13855.4 001265665.1_29629001_1 - 3.1e-67 222.1 45.6 1.5e-15 56.5 8.1 7.5 3 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.5 001265665.1_29629001_1 - 1.7e-35 120.2 45.1 2.9e-07 30.5 0.2 10.1 5 3 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001265665.1_29629001_1 - 2.4e-17 62.8 10.9 4.5e-07 29.4 0.3 4.3 1 1 4 5 5 5 5 Leucine-rich repeat LRRNT PF01462.16 001265665.1_29629001_1 - 2.9e-07 29.8 3.8 6.6e-07 28.7 1.9 2.7 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.31 001265665.1_29629001_1 - 5.2e-06 26.1 34.9 1.3 9.7 0.2 12.6 13 1 0 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.4 001265665.1_29629001_1 - 0.16 12.0 35.6 0.28 11.2 0.1 10.5 12 0 0 12 12 12 0 Leucine Rich repeat FXMRP1_C_core PF12235.6 001265665.1_29629001_2 - 3.4 8.2 5.4 5.5 7.5 5.4 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal PGM_PMM_I PF02878.14 001257491.1_29625001_3 - 2.2e-39 134.2 0.3 3.4e-39 133.6 0.3 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.14 001257491.1_29625001_3 - 3.6e-31 107.6 0.0 6e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.14 001257491.1_29625001_3 - 1.2e-17 64.2 0.0 3.7e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.18 001257491.1_29625001_3 - 1.5e-05 25.0 0.0 4.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.23 001280254.1_39724001_1 - 5.6e-26 91.3 0.0 7.6e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280254.1_39724001_1 - 1.7e-13 50.3 0.0 2.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CK1gamma_C PF12605.6 001280254.1_39724001_1 - 3.9e-13 50.3 12.5 1.6e-08 35.5 0.6 2.7 2 1 1 3 3 3 2 Casein kinase 1 gamma C terminal PAS_3 PF08447.10 001287465.1_39525001_1 - 2e-24 85.5 0.2 3.8e-18 65.4 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS PF00989.23 001287465.1_39525001_1 - 5.2e-23 81.1 0.0 6.1e-15 55.1 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001287465.1_39525001_1 - 1.5e-22 79.7 0.4 4.5e-20 71.7 0.2 2.8 2 1 0 2 2 2 2 PAS domain HLH PF00010.24 001287465.1_39525001_1 - 3.7e-15 55.5 1.1 9e-15 54.3 1.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001287465.1_39525001_1 - 2.8e-09 37.0 0.0 3.9e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001287465.1_39525001_1 - 0.0013 18.8 0.0 0.85 9.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PRAS PF15798.3 001287465.1_39525001_1 - 0.1 13.1 0.2 0.1 13.1 0.2 2.3 3 0 0 3 3 3 0 Proline-rich AKT1 substrate 1 Neur_chan_LBD PF02931.21 001266926.1_29624001_3 - 2.3e-53 180.7 0.0 3.1e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.14 001266926.1_29624001_3 - 4.3e-38 131.6 5.4 4e-33 115.3 1.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region LRR_8 PF13855.4 001285574.1_09026001_1 - 1.5e-51 171.8 61.3 1e-12 47.5 1.8 10.6 4 3 8 12 12 12 11 Leucine rich repeat TIR PF01582.18 001285574.1_09026001_1 - 6.6e-33 113.8 0.1 1.2e-32 113.0 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001285574.1_09026001_1 - 1.2e-31 107.9 52.9 3.2e-07 30.4 1.6 10.0 7 2 2 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.31 001285574.1_09026001_1 - 2.3e-13 48.4 50.4 0.99 10.0 0.2 15.6 15 2 1 16 16 16 5 Leucine Rich Repeat LRR_9 PF14580.4 001285574.1_09026001_1 - 2.6e-11 43.2 18.4 0.0011 18.4 0.1 5.1 2 2 3 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.4 001285574.1_09026001_1 - 4.5e-09 36.2 13.2 6.8e-05 22.7 0.1 4.6 2 2 3 5 5 5 3 Leucine rich repeats (6 copies) TIR_2 PF13676.4 001285574.1_09026001_1 - 5e-09 36.3 0.1 9.7e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001285574.1_09026001_1 - 1.3e-06 27.8 51.8 0.31 11.1 0.4 13.1 14 0 0 14 14 14 3 Leucine Rich repeat DUF1863 PF08937.9 001285574.1_09026001_1 - 4.1e-05 23.8 0.3 0.00016 21.9 0.3 1.9 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) CBP_BcsR PF10945.6 001285574.1_09026001_1 - 0.28 10.5 1.7 0.89 8.9 0.2 2.7 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR zf-C2H2_6 PF13912.4 001285574.1_09026001_3 - 0.061 13.2 1.3 0.21 11.5 1.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C4 PF00105.16 001266910.2_29625001_3 - 3e-31 107.5 17.5 5.5e-31 106.7 17.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001266910.2_29625001_3 - 2.3e-30 105.6 0.0 4.1e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ank_4 PF13637.4 001261721.1_29623001_1 - 4.1e-32 110.0 9.0 5.7e-10 39.4 0.1 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.28 001261721.1_29623001_1 - 9.2e-31 104.8 3.6 2.1e-07 30.9 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.5 001261721.1_29623001_1 - 2.5e-29 101.6 2.1 1.4e-13 51.1 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.4 001261721.1_29623001_1 - 7.3e-23 78.1 2.9 0.0006 19.9 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.4 001261721.1_29623001_1 - 1.6e-20 72.7 6.8 7.4e-10 38.8 0.7 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SOCS_box PF07525.14 001261721.1_29623001_1 - 1.5e-08 34.7 0.5 2.9e-08 33.8 0.5 1.5 1 0 0 1 1 1 1 SOCS box Thioredoxin PF00085.18 001267834.1_49826001_2 - 5.5e-98 321.7 0.2 6.7e-32 109.4 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.4 001267834.1_49826001_2 - 1.5e-24 86.9 7.2 2.1e-17 63.5 1.2 4.0 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001267834.1_49826001_2 - 3.7e-15 55.9 0.4 0.006 16.8 0.0 6.4 4 2 2 6 6 6 3 Thioredoxin-like OST3_OST6 PF04756.11 001267834.1_49826001_2 - 4.1e-15 55.8 0.0 3.8e-05 23.0 0.0 3.2 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 001267834.1_49826001_2 - 1.1e-14 54.7 1.9 0.00074 19.8 0.0 4.2 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.4 001267834.1_49826001_2 - 3.8e-13 49.3 0.0 0.0067 16.5 0.0 4.0 4 0 0 4 4 4 3 Thioredoxin-like Calsequestrin PF01216.15 001267834.1_49826001_2 - 1.4e-09 37.4 0.1 1.4e-09 37.4 0.1 3.1 2 1 1 4 4 3 1 Calsequestrin AhpC-TSA PF00578.19 001267834.1_49826001_2 - 2.5e-08 33.7 0.5 0.4 10.5 0.0 4.3 4 1 0 4 4 4 3 AhpC/TSA family Redoxin PF08534.8 001267834.1_49826001_2 - 4.6e-05 23.0 0.3 4.7 6.7 0.0 4.3 4 0 0 4 4 4 1 Redoxin TraF PF13728.4 001267834.1_49826001_2 - 5.1e-05 23.1 0.0 0.094 12.4 0.0 3.5 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.4 001267834.1_49826001_2 - 6.8e-05 22.9 3.4 3.6 7.6 0.0 4.6 4 0 0 4 4 4 1 Thioredoxin DUF836 PF05768.12 001267834.1_49826001_2 - 0.00045 20.4 0.0 38 4.7 0.0 4.2 4 0 0 4 4 4 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.9 001267834.1_49826001_2 - 0.00059 19.6 0.0 7.2 6.5 0.0 3.7 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Ribosomal_60s PF00428.17 001267834.1_49826001_2 - 0.0012 19.2 4.4 0.0032 17.8 4.4 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Thioredoxin_9 PF14595.4 001267834.1_49826001_2 - 0.0071 16.0 0.1 3.9 7.1 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin DSBA PF01323.18 001267834.1_49826001_2 - 0.073 12.7 1.2 70 3.0 0.1 4.3 3 3 2 5 5 5 0 DSBA-like thioredoxin domain FAM176 PF14851.4 001267834.1_49826001_2 - 0.08 12.5 1.8 0.15 11.6 1.8 1.3 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.14 001267834.1_49826001_2 - 0.1 11.6 1.4 0.24 10.4 1.2 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.10 001267834.1_49826001_2 - 3 5.8 7.7 4.4 5.3 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family LAT PF15234.4 001267834.1_49826001_2 - 5.6 6.5 11.4 35 3.9 9.4 2.8 3 0 0 3 3 3 0 Linker for activation of T-cells CENP-B_dimeris PF09026.8 001267834.1_49826001_2 - 9.1 6.6 17.2 5.5 7.3 14.2 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cofilin_ADF PF00241.18 001244461.1_49823001_3 - 1.9e-33 115.2 0.8 2.2e-33 115.0 0.1 1.4 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein Pro_isomerase PF00160.19 001244421.1_49825001_3 - 7.4e-51 172.4 2.3 1.3e-50 171.6 0.2 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.30 001244421.1_49825001_3 - 4.7e-12 46.1 2.3 0.022 15.5 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001244421.1_49825001_3 - 0.001 19.2 0.0 0.82 9.9 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF505 PF04458.10 001244421.1_49825001_3 - 0.0054 15.0 0.0 0.0096 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF505) Ge1_WD40 PF16529.3 001244421.1_49825001_3 - 0.072 11.9 0.2 21 3.8 0.0 3.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Interferon PF00143.17 001009198.1_22422001_1 - 3.2e-58 196.3 0.2 3.6e-58 196.1 0.2 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Sema PF01403.17 001265715.1_29628001_2 - 9.7e-116 386.9 0.0 1.4e-115 386.4 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.23 001265715.1_29628001_2 - 0.00017 21.9 7.3 0.00047 20.5 7.3 1.8 1 0 0 1 1 1 1 Plexin repeat NCD2 PF04905.11 001257641.1_29628001_3 - 3.4e-64 215.4 0.4 7.3e-64 214.3 0.4 1.5 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) Nab1 PF04902.10 001257641.1_29628001_3 - 2.2e-59 200.8 0.8 3.2e-59 200.2 0.8 1.2 1 0 0 1 1 1 1 Conserved region in Nab1 NCD1 PF04904.11 001257641.1_29628001_3 - 6.1e-41 138.2 0.0 1.1e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) Laminin_G_2 PF02210.22 001278391.1_29629001_3 - 5.3e-89 295.1 0.2 3.5e-24 85.6 0.1 4.2 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.21 001278391.1_29629001_3 - 1.8e-60 202.7 0.0 5.3e-17 62.1 0.0 4.3 4 0 0 4 4 4 4 Laminin G domain F5_F8_type_C PF00754.23 001278391.1_29629001_3 - 8.5e-22 77.5 0.0 2.1e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain EGF PF00008.25 001278391.1_29629001_3 - 5.8e-07 29.6 19.6 0.0009 19.4 6.1 3.2 2 0 0 2 2 2 2 EGF-like domain Laminin_G_3 PF13385.4 001278391.1_29629001_3 - 0.00041 20.4 0.0 5 7.1 0.0 3.8 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.5 001278391.1_29629001_3 - 3 8.5 13.9 0.17 12.5 4.2 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF FEZ PF07763.11 001261621.2_29624001_1 - 5.9e-83 278.2 23.2 7.6e-83 277.8 23.2 1.1 1 0 0 1 1 1 1 FEZ-like protein EURL PF06937.9 001261621.2_29624001_1 - 0.0053 16.1 3.9 0.017 14.4 3.4 1.9 1 1 0 1 1 1 1 EURL protein Ribosomal_S13 PF00416.20 001261621.2_29624001_1 - 0.13 12.5 0.7 0.61 10.3 0.0 2.1 1 1 1 2 2 2 0 Ribosomal protein S13/S18 DUF5102 PF17104.3 001261621.2_29624001_1 - 1.3 8.9 12.5 0.69 9.8 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) VWA_2 PF13519.4 001171301.1_37923001_1 - 1e-24 87.1 0.1 9.6e-24 84.0 0.0 2.6 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.26 001171301.1_37923001_1 - 1.8e-07 31.4 0.0 5.1e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.12 001171301.1_37923001_1 - 4.5e-07 29.7 0.1 7.5e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.18 001171301.1_37923001_1 - 4.8e-07 29.1 10.0 0.00012 21.6 0.4 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif Glypican PF01153.17 001265741.1_29626001_2 - 4.8e-233 774.9 5.4 6e-233 774.6 5.4 1.0 1 0 0 1 1 1 1 Glypican DUF1910 PF08928.8 001265741.1_29626001_2 - 0.047 13.6 0.8 0.34 10.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) adh_short PF00106.23 001267882.1_39523001_1 - 5.7e-47 159.6 0.1 7e-47 159.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001267882.1_39523001_1 - 1.8e-27 96.3 0.0 2.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.8 001267882.1_39523001_1 - 0.018 14.3 0.0 0.062 12.5 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) FixP_N PF14715.4 001267882.1_39523001_1 - 0.52 10.0 1.9 1.9 8.2 2.3 1.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP BIR PF00653.19 001266181.1_29625001_1 - 6.1e-23 81.2 2.3 1.3e-22 80.2 2.3 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Mtc PF03820.15 001261167.1_29624001_2 - 2.4e-135 450.5 1.2 2.8e-135 450.2 1.2 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier Crystall PF00030.17 001082130.2_37922001_2 - 2.2e-60 200.7 7.6 1.1e-29 102.3 0.4 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001082130.2_37922001_2 - 0.0011 18.7 0.9 0.17 11.7 0.0 2.7 2 0 0 2 2 2 2 Peptidase inhibitor family I36 Yippee-Mis18 PF03226.12 001261807.1_29624001_1 - 3.6e-12 46.3 0.3 3.6e-12 46.3 0.3 1.6 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATPgrasp_YheCD PF14398.4 001261807.1_29624001_1 - 0.095 11.8 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 YheC/D like ATP-grasp DSPc PF00782.18 001244377.1_49823001_1 - 2e-18 66.3 0.1 2.9e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001244377.1_49823001_1 - 0.00037 20.0 0.1 0.00058 19.4 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.4 001244377.1_49823001_1 - 0.0055 17.0 0.1 0.0086 16.4 0.1 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.4 001244377.1_49823001_1 - 0.023 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.10 001244377.1_49823001_1 - 0.037 14.2 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain ubiquitin PF00240.21 001266701.1_29625001_3 - 2.4e-19 68.7 0.0 4e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 001266701.1_29625001_3 - 5.1e-08 32.5 0.0 7.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001266701.1_29625001_3 - 0.098 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MgtE PF01769.14 001243667.1_49829001_2 - 2.1e-52 176.6 27.2 6.4e-30 103.9 3.0 3.0 3 0 0 3 3 3 2 Divalent cation transporter NOT2_3_5 PF04153.16 001265869.1_29626001_3 - 1.5e-30 105.9 0.2 2.6e-30 105.1 0.2 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Paf67 PF10255.7 001244086.1_49824001_1 - 1.3e-176 587.4 10.8 1.9e-176 586.8 10.8 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.15 001244086.1_49824001_1 - 0.0038 17.1 0.4 0.062 13.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.26 001244086.1_49824001_1 - 0.021 14.5 0.3 0.6 9.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001244086.1_49824001_1 - 0.047 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Na_Ca_ex PF01699.22 001252181.1_39524001_1 - 8.9e-52 174.9 39.7 2.9e-28 98.6 14.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CAP PF00188.24 001283995.1_29523001_2 - 5.8e-24 85.2 2.8 8.3e-24 84.7 2.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Crisp PF08562.8 001283995.1_29523001_2 - 1.4e-19 70.3 21.9 4e-19 68.8 21.9 1.9 1 0 0 1 1 1 1 Crisp V-set PF07686.15 001244821.1_49825001_1 - 5.2e-21 74.7 0.0 7.2e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.23 001244821.1_49825001_1 - 2.9e-07 30.4 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.4 001244821.1_49825001_1 - 0.0048 17.3 0.0 0.01 16.3 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001244821.1_49825001_1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.4 001244821.1_49825001_1 - 0.034 14.4 0.0 0.31 11.3 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin domain GST_C PF00043.23 001243545.1_49823001_1 - 5.2e-06 26.5 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001243545.1_49823001_1 - 7.1e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001243545.1_49823001_1 - 8.3e-05 22.6 0.2 0.00021 21.3 0.0 1.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain BAT2_N PF07001.9 001242745.1_37629001_1 - 3.2e-70 236.4 13.1 3.2e-70 236.4 13.1 3.5 3 0 0 3 3 3 1 BAT2 N-terminus BAR_3 PF16746.3 001261353.1_29627001_1 - 2.4e-77 259.7 20.0 3.4e-77 259.2 20.0 1.2 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.25 001261353.1_29627001_1 - 1e-41 142.1 0.0 3e-41 140.6 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.27 001261353.1_29627001_1 - 3.3e-07 30.6 0.1 9e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 PH domain Arfaptin PF06456.11 001261353.1_29627001_1 - 0.058 12.8 5.7 0.14 11.6 5.7 1.6 1 0 0 1 1 1 0 Arfaptin-like domain DUF1073 PF06381.9 001261353.1_29627001_1 - 0.081 11.5 0.2 0.17 10.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) Patched PF02460.16 001261353.1_29627001_1 - 3.4 5.5 5.8 2.6 5.9 3.1 1.8 1 1 1 2 2 2 0 Patched family HEAT PF02985.20 001261575.1_29628001_2 - 3.7e-29 98.1 11.8 0.00067 19.6 0.1 11.1 11 0 0 11 11 11 7 HEAT repeat HEAT_EZ PF13513.4 001261575.1_29628001_2 - 4.6e-29 100.3 9.9 1.2e-12 47.8 0.0 10.4 10 1 1 11 11 10 4 HEAT-like repeat HEAT_2 PF13646.4 001261575.1_29628001_2 - 5.4e-19 68.2 0.0 3.7e-05 23.9 0.0 7.0 5 3 2 7 7 7 4 HEAT repeats Cnd1 PF12717.5 001261575.1_29628001_2 - 1.3e-16 60.9 1.1 0.002 18.0 0.6 4.4 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.17 001261575.1_29628001_2 - 5.3e-16 58.2 0.1 4.6e-15 55.2 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.21 001261575.1_29628001_2 - 5.7e-16 57.8 10.9 0.0032 17.3 0.0 7.6 8 0 0 8 8 7 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.5 001261575.1_29628001_2 - 9e-14 51.7 0.5 0.002 18.5 0.5 6.4 5 2 3 8 8 8 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.18 001261575.1_29628001_2 - 7e-09 34.6 6.6 0.0032 16.0 0.1 4.8 3 2 0 3 3 3 3 Adaptin N terminal region UNC45-central PF11701.6 001261575.1_29628001_2 - 5.3e-05 23.1 3.3 0.00057 19.7 0.3 3.4 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.6 001261575.1_29628001_2 - 0.00018 21.0 0.4 1.5 8.2 0.0 4.6 4 2 1 5 5 5 1 CLASP N terminal Dopey_N PF04118.12 001261575.1_29628001_2 - 0.00085 18.4 0.6 0.0038 16.3 0.0 2.3 2 1 0 2 2 2 1 Dopey, N-terminal MMS19_C PF12460.6 001261575.1_29628001_2 - 0.0013 17.9 4.9 0.76 8.7 0.1 4.6 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.6 001261575.1_29628001_2 - 0.004 16.9 0.5 8.6 6.1 0.0 4.9 6 1 1 7 7 7 1 Domain of unknown function (DUF3385) DUF3437 PF11919.6 001261575.1_29628001_2 - 0.0063 16.3 0.0 0.71 9.7 0.0 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) TIP120 PF08623.8 001261575.1_29628001_2 - 0.014 15.1 0.1 1.3 8.7 0.3 3.4 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Xpo1 PF08389.10 001261575.1_29628001_2 - 0.022 14.7 1.2 4.1 7.3 0.1 4.6 3 1 2 5 5 5 0 Exportin 1-like protein DUF2573 PF10835.6 001261575.1_29628001_2 - 0.077 13.2 0.0 0.31 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) RTP1_C1 PF10363.7 001261575.1_29628001_2 - 0.4 10.7 1.3 2.6 8.1 0.1 3.1 3 0 0 3 3 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Aldedh PF00171.20 001244467.1_49824001_3 - 1.3e-163 544.7 1.2 1.5e-163 544.5 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.9 001244467.1_49824001_3 - 0.019 14.3 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Condensin2nSMC PF12422.6 001258148.1_29628001_3 - 8.3e-57 191.4 3.3 1.8e-56 190.4 0.3 3.3 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.20 001258148.1_29628001_3 - 4.8e-08 32.4 0.2 8.4 6.8 0.0 6.2 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.5 001258148.1_29628001_3 - 1.9e-05 24.6 1.1 0.017 15.0 0.0 4.1 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.18 001258148.1_29628001_3 - 2.1e-05 23.2 1.0 0.0013 17.3 0.0 2.7 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.4 001258148.1_29628001_3 - 0.0041 17.3 0.1 0.61 10.4 0.0 3.4 3 1 0 3 3 3 1 HEAT repeats RICTOR_M PF14666.4 001258148.1_29628001_3 - 0.028 14.0 0.4 3.5 7.3 0.1 2.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain TIP120 PF08623.8 001258148.1_29628001_3 - 0.14 11.8 1.0 0.58 9.8 0.1 2.5 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) RPAP3_C PF13877.4 001258148.1_29628001_3 - 0.2 12.1 1.2 4.5 7.8 0.0 3.6 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 DUF577 PF04510.10 001258148.1_29628001_3 - 0.24 11.1 3.9 0.68 9.7 0.0 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF577) zf-SAP30 PF13866.4 001261790.1_29624001_1 - 2.8e-37 126.5 3.4 6.3e-37 125.3 3.4 1.6 1 0 0 1 1 1 1 SAP30 zinc-finger SAP30_Sin3_bdg PF13867.4 001261790.1_29624001_1 - 2.4e-24 85.2 0.9 3.9e-24 84.6 0.9 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Xpo1 PF08389.10 001266048.2_29629001_2 - 5.9e-28 97.7 6.3 1.6e-26 93.0 0.7 3.9 3 1 1 4 4 4 2 Exportin 1-like protein IFRD PF05004.11 001266048.2_29629001_2 - 0.024 13.6 0.4 1.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) EB1 PF03271.15 001280315.1_39724001_3 - 3.4e-17 62.2 1.1 5.5e-17 61.6 0.1 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.29 001280315.1_39724001_3 - 2e-14 53.5 0.3 3e-14 53.0 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.6 001280315.1_39724001_3 - 0.048 13.4 0.1 0.098 12.4 0.1 1.4 1 0 0 1 1 1 0 CAMSAP CH domain NOT2_3_5 PF04153.16 001133145.1_43527001_1 - 7.9e-28 97.0 0.1 1.8e-27 95.8 0.1 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Tubulin-binding PF00418.17 001277940.1_29629001_3 - 4.5e-56 186.4 26.9 8.3e-15 54.4 5.4 5.3 5 0 0 5 5 5 4 Tau and MAP protein, tubulin-binding repeat WD40 PF00400.30 001252610.1_32324001_1 - 1.9e-53 177.1 24.5 3.2e-10 40.3 0.2 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001252610.1_32324001_1 - 1.7e-29 101.8 2.4 4.8e-08 33.1 0.1 6.6 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001252610.1_32324001_1 - 1.2e-11 44.7 0.5 0.00082 19.2 0.1 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.9 001252610.1_32324001_1 - 6.7e-10 38.5 0.1 3.8e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 LisH WD40_like PF17005.3 001252610.1_32324001_1 - 2.5e-05 23.6 0.0 0.063 12.5 0.0 3.1 4 1 0 4 4 4 2 WD40-like domain Coatomer_WDAD PF04053.12 001252610.1_32324001_1 - 4e-05 22.7 0.0 0.0031 16.5 0.0 2.4 2 0 0 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.3 001252610.1_32324001_1 - 0.00012 21.0 1.3 0.71 8.6 0.0 3.4 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.6 001252610.1_32324001_1 - 0.013 14.1 4.2 0.53 8.7 0.0 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 PD40 PF07676.10 001252610.1_32324001_1 - 0.03 14.1 0.0 0.46 10.4 0.0 3.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat K_channel_TID PF07941.9 001252610.1_32324001_1 - 0.037 14.4 5.9 0.074 13.4 5.9 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_hydro_11 PF00457.15 001252610.1_32324001_1 - 0.048 13.2 1.2 1.6 8.2 0.1 2.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 PCuAC PF04314.11 001252610.1_32324001_1 - 0.12 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Copper chaperone PCu(A)C IKI3 PF04762.10 001252610.1_32324001_1 - 0.19 9.6 0.5 4.4 5.0 0.1 2.6 2 1 1 3 3 3 0 IKI3 family ArfGap PF01412.16 001280261.1_39726001_2 - 4.8e-31 107.1 0.8 4.8e-31 107.1 0.8 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf TMF_DNA_bd PF12329.6 001280261.1_39726001_2 - 0.044 13.6 6.5 0.11 12.4 6.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding OCD_Mu_crystall PF02423.13 001266891.1_29623001_2 - 6.6e-116 386.6 0.1 7.5e-116 386.4 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.18 001266891.1_29623001_2 - 1.9e-10 40.8 0.0 3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.15 001266891.1_29623001_2 - 0.00013 22.3 0.0 0.00032 21.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.13 001266891.1_29623001_2 - 0.0002 21.5 0.3 0.00046 20.3 0.3 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OTCace PF00185.22 001266891.1_29623001_2 - 0.05 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NTP_transf_7 PF07984.10 001266603.1_29629001_2 - 1.2e-157 524.0 0.4 1.5e-157 523.7 0.4 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase BUD22 PF09073.8 001244566.1_49825001_1 - 3.2e-11 43.1 6.7 3.2e-11 43.1 6.7 3.0 1 1 1 2 2 2 1 BUD22 Sprouty PF05210.11 001204360.1_29624001_2 - 6e-26 90.9 24.3 6e-26 90.9 24.3 2.1 2 0 0 2 2 2 1 Sprouty protein (Spry) WH1 PF00568.21 001204360.1_29624001_2 - 7.2e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 WH1 domain SMC_ScpA PF02616.12 001204360.1_29624001_2 - 0.2 11.4 0.3 0.31 10.8 0.3 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA CH PF00307.29 001266221.1_29627001_2 - 9.2e-91 299.2 2.2 1.9e-25 89.0 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.4 001266221.1_29627001_2 - 5.8e-11 42.6 0.3 1.9e-10 40.9 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.30 001266221.1_29627001_2 - 2.3e-10 39.1 3.5 0.0001 21.4 0.7 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.4 001266221.1_29627001_2 - 5.8e-06 25.7 1.4 0.093 12.6 0.2 3.2 2 0 0 2 2 2 2 EF-hand domain CAMSAP_CH PF11971.6 001266221.1_29627001_2 - 1.9e-05 24.2 0.8 0.0006 19.5 0.0 3.3 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_5 PF13202.4 001266221.1_29627001_2 - 2.5e-05 23.4 7.2 0.0043 16.4 0.2 4.0 4 1 1 5 5 5 2 EF hand EF-hand_8 PF13833.4 001266221.1_29627001_2 - 0.0033 17.0 0.6 0.027 14.1 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair Metallophos PF00149.26 001261762.2_29623001_1 - 1.2e-39 136.9 0.1 1.6e-39 136.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.3 001261762.2_29623001_1 - 0.0013 19.0 1.5 0.0018 18.5 0.6 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.5 001261762.2_29623001_1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Patatin PF01734.20 001266037.1_29627001_1 - 9.8e-25 87.8 0.0 2.3e-24 86.6 0.0 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase SMC_ScpB PF04079.14 001266037.1_29627001_1 - 0.013 15.0 1.0 0.029 13.9 0.2 1.9 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB DARPP-32 PF05395.10 001266966.1_29624001_2 - 6.3e-38 130.4 11.1 9.3e-38 129.8 11.1 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 FAM193_C PF15914.3 001243850.1_49827001_3 - 2.6e-28 97.4 1.0 5.9e-28 96.2 1.0 1.6 1 0 0 1 1 1 1 FAM193 family C-terminal TIR_2 PF13676.4 001204347.1_32322001_1 - 1.5e-07 31.5 0.0 2.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001204347.1_32322001_1 - 4.9e-05 23.1 0.6 0.00088 19.0 0.0 2.7 3 0 0 3 3 3 1 TIR domain BAR_3_WASP_bdg PF10456.7 001257452.1_29626001_1 - 6.1e-109 362.8 3.1 7.9e-109 362.5 3.1 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.22 001257452.1_29626001_1 - 3.7e-20 71.9 1.1 3.7e-20 71.9 1.1 1.9 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.4 001257452.1_29626001_1 - 2.4e-11 43.2 0.0 4.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.26 001257452.1_29626001_1 - 1.2e-08 34.3 0.0 2.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001257452.1_29626001_1 - 7.5e-08 31.8 0.0 2.1e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.8 001257452.1_29626001_1 - 0.0018 17.7 2.2 0.067 12.6 0.6 2.8 1 1 1 2 2 2 2 Vps5 C terminal like PCIF1_WW PF12237.6 001257452.1_29626001_1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain HBM PF16591.3 001257452.1_29626001_1 - 0.12 11.7 0.0 0.57 9.4 0.0 1.8 1 1 1 2 2 2 0 Helical bimodular sensor domain Reo_sigmaC PF04582.10 001257452.1_29626001_1 - 0.19 11.0 0.1 0.78 8.9 0.0 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Homeobox_KN PF05920.9 001244289.1_49824001_1 - 3.4e-17 61.9 0.9 6.3e-17 61.1 0.9 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.27 001244289.1_49824001_1 - 5.1e-07 29.3 1.2 5.1e-07 29.3 1.2 1.9 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.6 001244289.1_49824001_1 - 0.15 11.4 0.5 0.29 10.5 0.2 1.6 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Glypican PF01153.17 001266539.1_29628001_3 - 1.3e-221 737.1 0.0 1.9e-221 736.6 0.0 1.0 1 0 0 1 1 1 1 Glypican Tetraspannin PF00335.18 001261716.1_29624001_3 - 1.5e-46 158.8 8.7 2.5e-46 158.0 8.7 1.3 1 0 0 1 1 1 1 Tetraspanin family FAM104 PF15434.4 001261522.1_29622001_2 - 1.1e-52 177.0 3.2 1.4e-52 176.7 3.2 1.1 1 0 0 1 1 1 1 Family 104 RNase_HII PF01351.16 001244444.1_49823001_1 - 2.8e-51 174.1 0.0 3.5e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Rrn6 PF10214.7 001244444.1_49823001_2 - 1.2 7.3 9.5 1.5 7.0 9.5 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor 7tm_1 PF00001.19 001001618.1_49827001_3 - 3.9e-49 167.1 18.4 6.1e-49 166.5 18.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001618.1_49827001_3 - 3.4e-06 26.5 20.2 4.9e-06 26.0 20.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Not3 PF04065.13 001171391.1_37925001_1 - 3.9e-95 317.5 27.5 5.3e-95 317.1 27.5 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.16 001171391.1_37925001_1 - 1.1e-40 138.7 9.6 2.8e-40 137.3 9.6 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ZnuA PF01297.15 001171391.1_37925001_1 - 0.47 9.7 3.7 0.58 9.4 2.7 1.4 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Syntaxin_2 PF14523.4 001171391.1_37925001_1 - 0.75 10.1 8.6 0.18 12.0 1.7 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Swi5 PF07061.9 001171391.1_37925001_1 - 0.95 9.4 8.2 3.4 7.7 0.7 2.7 2 0 0 2 2 2 0 Swi5 DUF4407 PF14362.4 001171391.1_37925001_1 - 2.6 7.2 9.8 3.9 6.6 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) USP8_dimer PF08969.9 001261017.1_29624001_1 - 2.1e-18 66.5 0.1 2.1e-18 66.5 0.1 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain JAB PF01398.19 001261017.1_29624001_1 - 2.5e-18 66.0 0.0 6.9e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.4 001261017.1_29624001_1 - 2.7e-07 30.2 0.1 5.3e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CHDCT2 PF08074.9 001261017.1_29624001_1 - 0.14 12.2 3.7 0.25 11.4 3.7 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain MARVEL PF01284.21 001243922.1_49823001_2 - 3.6e-16 59.4 17.0 3.6e-16 59.4 17.0 1.8 2 0 0 2 2 2 1 Membrane-associating domain DUF4133 PF13571.4 001243922.1_49823001_2 - 8.1 6.7 9.7 0.6 10.4 4.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) GTP_EFTU PF00009.25 001284594.1_29524001_3 - 3.2e-54 183.3 0.0 4.5e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.15 001284594.1_29524001_3 - 1e-39 135.2 0.0 2.3e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.23 001284594.1_29524001_3 - 8.7e-15 54.8 2.2 9.3e-15 54.7 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.21 001284594.1_29524001_3 - 0.00052 19.9 0.2 0.013 15.4 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.4 001284594.1_29524001_3 - 0.011 15.6 1.9 0.018 14.9 0.3 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 ANAPC15 PF15243.4 001082007.1_37923001_2 - 3.1 8.1 5.8 10 6.5 5.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Mo25 PF08569.9 001011917.1_45723001_1 - 1.2e-137 458.6 12.1 1.4e-137 458.3 12.1 1.0 1 0 0 1 1 1 1 Mo25-like IFRD PF05004.11 001011917.1_45723001_1 - 0.059 12.4 0.6 1.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.4 001011917.1_45723001_1 - 0.1 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats IL4 PF00727.16 001257263.1_09921001_2 - 9.2e-33 112.6 0.0 1.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Interleukin 4 CEBP1_N PF16368.3 001260826.1_29627001_1 - 4.5e-158 525.5 11.1 6.5e-158 525.0 11.1 1.2 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein 1 N-terminus RRM_7 PF16367.3 001260826.1_29627001_1 - 6.9e-33 112.5 0.0 1.8e-32 111.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.3 001260826.1_29627001_1 - 1.2e-23 83.0 7.3 1.2e-23 83.0 7.3 2.3 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.20 001260826.1_29627001_1 - 4.6e-08 32.6 0.0 0.0053 16.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.20 001093786.1_39523001_3 - 5.2e-26 90.1 0.7 9.1e-26 89.4 0.7 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.9 001093786.1_39523001_3 - 0.021 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain NolX PF05819.9 001260758.1_29624001_1 - 0.73 7.8 1.4 1 7.3 1.4 1.0 1 0 0 1 1 1 0 NolX protein tRNA-synt_2d PF01409.18 001260758.1_29624001_3 - 1.3e-90 303.0 0.0 1.8e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) MarR_2 PF12802.5 001260758.1_29624001_3 - 6.1e-05 22.7 0.5 0.00024 20.8 0.5 2.0 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.10 001260758.1_29624001_3 - 0.00022 21.0 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 HTH domain tRNA-synt_2 PF00152.18 001260758.1_29624001_3 - 0.0011 18.0 0.3 0.0041 16.1 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF1204 PF06721.9 001260758.1_29624001_3 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) OSTMP1 PF09777.7 001261748.1_29626001_2 - 3.9e-85 284.9 15.0 6e-85 284.3 15.0 1.3 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor HAUS2 PF15003.4 001243905.1_49823001_3 - 1.9e-63 213.5 3.7 2.3e-63 213.2 3.7 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Vac_Fusion PF02346.14 001243905.1_49823001_3 - 0.023 14.2 6.7 0.12 11.9 0.6 3.2 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Retinal PF15449.4 001243905.1_49823001_3 - 0.038 11.7 0.1 0.051 11.3 0.1 1.0 1 0 0 1 1 1 0 Retinal protein DpnII PF04556.10 001243905.1_49823001_3 - 0.083 12.1 1.5 0.084 12.0 0.2 1.5 2 0 0 2 2 2 0 DpnII restriction endonuclease RDD PF06271.10 001258124.2_29629001_2 - 1.2e-09 38.3 5.1 1e-08 35.4 5.1 2.2 1 1 0 1 1 1 1 RDD family JAB PF01398.19 001243023.1_49825001_3 - 6.9e-45 151.7 0.5 1.1e-43 147.8 0.5 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.4 001243023.1_49825001_3 - 2.4e-06 27.2 0.1 4.5e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Solute_trans_a PF03619.14 001265954.1_29623001_1 - 3.6e-34 118.4 8.0 4.4e-34 118.1 8.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-C4 PF00105.16 001082067.2_37924001_1 - 1.8e-27 95.4 16.6 3.3e-27 94.6 16.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001082067.2_37924001_1 - 1.6e-18 66.9 0.5 4.1e-18 65.6 0.5 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor C1_2 PF03107.14 001082067.2_37924001_1 - 8.9 6.6 8.6 1.2 9.3 0.6 2.4 2 0 0 2 2 2 0 C1 domain Adap_comp_sub PF00928.19 001260598.1_29624001_1 - 1.9e-81 273.2 0.1 2.4e-81 272.8 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.18 001260598.1_29624001_1 - 1.4e-05 24.9 0.4 2.3e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.7 001260598.1_29624001_1 - 0.024 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain VWA_2 PF13519.4 001168950.1_40423001_1 - 1.9e-24 86.3 1.1 9.4e-24 84.0 0.0 2.7 4 1 0 4 4 4 1 von Willebrand factor type A domain VWA PF00092.26 001168950.1_40423001_1 - 3.3e-07 30.6 0.0 1e-06 29.0 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.12 001168950.1_40423001_1 - 4.1e-07 29.9 0.1 6.8e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.18 001168950.1_40423001_1 - 4.5e-07 29.2 10.0 0.00012 21.6 0.4 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif Mito_carr PF00153.25 001243357.1_49823001_2 - 1.7e-48 162.3 7.2 5.2e-16 58.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MARVEL PF01284.21 001266199.1_29623001_1 - 4.6e-22 78.5 13.1 7.9e-22 77.7 13.1 1.4 1 0 0 1 1 1 1 Membrane-associating domain Tme5_EGF_like PF09064.8 001266199.1_29623001_2 - 0.29 10.9 3.1 0.22 11.3 0.2 2.1 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like Crystallin PF00525.16 001242752.1_37622001_1 - 4.6e-29 100.3 5.4 1e-28 99.2 5.4 1.6 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.19 001242752.1_37622001_1 - 6.8e-26 90.3 0.1 8.2e-26 90.0 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Interferon PF00143.17 001135794.1_29622001_1 - 1.7e-66 223.2 6.3 2e-66 223.0 6.3 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain DDHD PF02862.15 001135794.1_29622001_1 - 0.025 14.6 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 DDHD domain CBF PF03914.15 001135794.1_29622001_1 - 0.058 13.3 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 CBF/Mak21 family Sel1 PF08238.10 001243566.2_49824001_3 - 2.3e-25 88.3 20.1 3.9e-06 27.2 0.3 6.0 6 0 0 6 6 6 5 Sel1 repeat TPR_6 PF13174.4 001243566.2_49824001_3 - 3.9e-05 23.9 9.7 2.8 8.6 0.2 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.15 001243566.2_49824001_3 - 0.00012 21.8 18.5 0.00024 20.8 1.2 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.4 001243566.2_49824001_3 - 0.00016 21.5 11.3 0.0055 16.7 0.5 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.4 001243566.2_49824001_3 - 0.0023 18.3 1.5 0.25 11.7 0.2 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat PPR PF01535.18 001243566.2_49824001_3 - 0.0049 16.9 0.2 0.56 10.4 0.1 3.2 2 0 0 2 2 2 1 PPR repeat TPR_16 PF13432.4 001243566.2_49824001_3 - 0.011 16.3 0.7 0.011 16.3 0.7 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001243566.2_49824001_3 - 0.035 14.2 0.1 0.035 14.2 0.1 3.0 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.26 001243566.2_49824001_3 - 0.045 13.5 0.7 0.045 13.5 0.7 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat PPR_2 PF13041.4 001243566.2_49824001_3 - 0.05 13.7 0.1 17 5.6 0.1 2.7 2 0 0 2 2 2 0 PPR repeat family TPR_11 PF13414.4 001243566.2_49824001_3 - 0.051 13.1 12.2 0.18 11.4 1.0 4.4 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.4 001243566.2_49824001_3 - 0.27 12.0 4.8 6.2 7.8 0.1 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat PIG-Y PF15159.4 001265768.1_29623001_2 - 1.5e-17 64.0 3.2 2.5e-17 63.3 3.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Trm112p PF03966.14 001265768.1_29623001_3 - 1e-07 32.2 0.0 4.1e-07 30.4 0.0 2.1 1 0 0 1 1 1 1 Trm112p-like protein MFS_1 PF07690.14 001260725.1_29627001_1 - 8.2e-12 44.6 32.7 3e-09 36.1 10.0 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.4 001260725.1_29627001_1 - 3.4e-07 29.0 10.0 6.8e-05 21.4 0.6 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Crystallin PF00525.16 001260901.1_29622001_1 - 7e-30 102.9 7.2 1.5e-29 101.9 7.2 1.6 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.19 001260901.1_29622001_1 - 7.8e-25 86.9 0.1 9.9e-25 86.5 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Sulfate_transp PF00916.18 001246662.1_09926001_1 - 1.6e-111 372.6 26.6 2.2e-111 372.2 26.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.19 001246662.1_09926001_1 - 9.9e-39 131.5 0.1 3e-38 129.9 0.1 1.9 2 0 0 2 2 2 1 STAS domain TMEM100 PF16311.3 001246662.1_09926001_1 - 0.16 11.4 3.7 4.7 6.7 0.8 3.0 2 0 0 2 2 2 0 Transmembrane protein 100 Crystallin PF00525.16 001242753.1_37622001_1 - 1.3e-25 89.2 1.5 2.4e-25 88.4 1.5 1.5 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.19 001242753.1_37622001_1 - 1.9e-22 79.2 0.0 2.4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Atg8 PF02991.14 001261138.1_29622001_3 - 8.1e-43 144.7 0.3 1e-42 144.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.11 001261138.1_29622001_3 - 3.2e-05 24.1 0.0 4.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Thioredoxin PF00085.18 001266045.2_29624001_1 - 1.2e-55 185.7 0.0 2.1e-25 88.5 0.1 3.2 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.4 001266045.2_29624001_1 - 4.3e-44 150.5 0.0 2.1e-35 122.2 0.0 3.1 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.11 001266045.2_29624001_1 - 3.6e-11 42.8 0.0 0.00096 18.5 0.0 3.2 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 001266045.2_29624001_1 - 3.5e-10 40.2 0.0 0.00021 21.6 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.4 001266045.2_29624001_1 - 6.1e-08 32.6 0.0 0.026 14.6 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.19 001266045.2_29624001_1 - 6.3e-07 29.2 0.1 0.0019 18.0 0.1 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.4 001266045.2_29624001_1 - 2.4e-06 27.6 0.0 0.023 14.9 0.0 4.0 4 1 1 5 5 5 1 Thioredoxin-like Redoxin PF08534.8 001266045.2_29624001_1 - 0.00041 19.9 0.1 0.15 11.6 0.0 2.5 2 0 0 2 2 2 2 Redoxin TraF PF13728.4 001266045.2_29624001_1 - 0.00051 19.8 0.0 2.2 7.9 0.0 3.5 4 0 0 4 4 4 2 F plasmid transfer operon protein DUF1798 PF08807.8 001266045.2_29624001_1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Thioredoxin_3 PF13192.4 001266045.2_29624001_1 - 0.076 12.9 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.4 001266045.2_29624001_1 - 0.09 12.8 0.8 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin Pro_dh PF01619.16 001266045.2_29624001_1 - 0.24 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Proline dehydrogenase IL6Ra-bind PF09240.8 001243634.1_49823001_2 - 1.4e-30 105.4 0.1 3.3e-30 104.2 0.1 1.7 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding fn3 PF00041.19 001243634.1_49823001_2 - 2.5e-06 27.6 1.8 0.024 14.9 0.3 3.3 3 0 0 3 3 3 2 Fibronectin type III domain EpoR_lig-bind PF09067.8 001243634.1_49823001_2 - 3.5e-06 27.0 0.6 1.2e-05 25.3 0.6 1.9 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding DUF3844 PF12955.5 001243634.1_49823001_2 - 0.075 13.0 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) ubiquitin PF00240.21 001244336.1_49823001_1 - 3.7e-07 29.6 0.0 6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.4 001244336.1_49823001_1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4227 PF14004.4 001244336.1_49823001_1 - 0.041 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) C1-set PF07654.13 001172856.1_09921001_1 - 1.1e-23 83.3 0.1 1.4e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001172856.1_09921001_1 - 2.8e-05 24.5 0.0 4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001172856.1_09921001_1 - 0.00013 21.8 0.0 0.00017 21.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Se-cys_synth_N PF12390.6 001172856.1_09921001_1 - 0.00093 19.2 0.2 0.0016 18.4 0.2 1.4 1 0 0 1 1 1 1 Selenocysteine synthase N terminal Ig_2 PF13895.4 001172856.1_09921001_1 - 0.0038 17.4 0.0 0.0051 17.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001172856.1_09921001_1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin domain Sema PF01403.17 001266494.1_29628001_1 - 3e-131 438.0 0.0 4.1e-131 437.5 0.0 1.2 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.17 001266494.1_29628001_1 - 1.4e-46 156.3 96.2 1.5e-11 44.2 8.3 7.5 7 0 0 7 7 7 6 Thrombospondin type 1 domain Aa_trans PF01490.16 001246361.1_39725001_1 - 7.2e-110 367.4 34.3 8.5e-110 367.1 34.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3262 PF11660.6 001246361.1_39725001_1 - 0.053 13.8 0.2 0.053 13.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) Hormone_recep PF00104.28 001257610.1_29625001_3 - 2.6e-38 131.6 0.0 4.1e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.6 001257610.1_29625001_3 - 8.7e-37 125.5 15.0 1.5e-36 124.7 15.0 1.4 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.16 001257610.1_29625001_3 - 1.8e-31 108.3 15.7 3.2e-31 107.5 15.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) SIS PF01380.20 001265907.1_29628001_3 - 2.1e-69 231.3 0.1 2.4e-35 121.1 0.0 2.2 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.4 001265907.1_29628001_3 - 2e-16 60.3 0.0 4.5e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.4 001265907.1_29628001_3 - 3.9e-12 46.1 0.0 8.8e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.4 001265907.1_29628001_3 - 4.4e-05 22.4 0.0 7.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.19 001265907.1_29628001_3 - 0.0041 15.8 0.0 0.0074 14.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.4 001265907.1_29628001_3 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 SIS domain GTP_EFTU PF00009.25 001266936.2_29626001_1 - 6.2e-66 221.5 0.0 9.8e-66 220.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.4 001266936.2_29626001_1 - 1e-27 95.9 0.0 2.9e-27 94.4 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.22 001266936.2_29626001_1 - 6.7e-23 80.4 0.0 1.9e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.16 001266936.2_29626001_1 - 2.7e-11 43.2 0.0 6.1e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.23 001266936.2_29626001_1 - 1.2e-08 35.1 0.0 2.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.3 001266936.2_29626001_1 - 5.4e-07 29.4 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.21 001266936.2_29626001_1 - 0.00078 19.4 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.3 001266936.2_29626001_1 - 0.0021 18.4 0.0 0.032 14.6 0.0 2.8 3 0 0 3 3 3 1 Avirulence AvrPtoB, BAK1-binding domain AIG1 PF04548.14 001266936.2_29626001_1 - 0.037 13.2 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.16 001266936.2_29626001_1 - 0.077 12.4 0.0 0.57 9.6 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B Interferon PF00143.17 001130219.1_49822001_1 - 8.7e-66 220.9 0.3 9.9e-66 220.7 0.3 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Thioredoxin PF00085.18 001266635.1_29625001_2 - 2.1e-63 210.6 0.0 1.8e-30 104.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.4 001266635.1_29625001_2 - 2.6e-10 40.6 0.2 0.00054 20.3 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.4 001266635.1_29625001_2 - 1.6e-08 34.6 0.0 7.1e-05 22.7 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.4 001266635.1_29625001_2 - 8.6e-08 32.1 0.0 0.0033 17.4 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.11 001266635.1_29625001_2 - 2.1e-07 30.5 0.0 0.00057 19.2 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.4 001266635.1_29625001_2 - 5.7e-07 29.6 0.2 0.047 13.9 0.0 4.4 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_3 PF13192.4 001266635.1_29625001_2 - 0.0021 18.0 0.0 0.92 9.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.19 001266635.1_29625001_2 - 0.0028 17.4 0.1 2.7 7.8 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.4 001266635.1_29625001_2 - 0.098 12.3 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.4 001266635.1_29625001_2 - 0.11 12.6 0.2 3.9 7.5 0.0 2.8 2 1 1 3 3 3 0 Thioredoxin HyaE PF07449.9 001266635.1_29625001_2 - 0.12 12.2 0.0 9.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE LRR_8 PF13855.4 001265627.1_29629001_1 - 1.1e-60 201.1 90.8 5e-15 54.9 6.0 7.0 3 2 6 9 9 9 8 Leucine rich repeat LRR_4 PF12799.5 001265627.1_29629001_1 - 2e-18 66.0 43.6 1.1e-05 25.6 0.6 7.3 6 1 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001265627.1_29629001_1 - 5.4e-15 55.4 0.0 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001265627.1_29629001_1 - 1.7e-05 24.3 14.8 0.2 11.0 0.2 4.2 2 2 2 4 4 4 4 Leucine-rich repeat LRRNT PF01462.16 001265627.1_29629001_1 - 0.0015 18.0 0.4 0.0015 18.0 0.4 2.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain GRP PF07172.9 001265627.1_29629001_1 - 0.051 14.1 0.0 0.088 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycine rich protein family IncA PF04156.12 001265627.1_29629001_1 - 0.092 12.4 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 IncA protein LRR_1 PF00560.31 001265627.1_29629001_1 - 7.4 7.4 45.4 1.1 9.9 0.3 10.6 11 0 0 11 11 11 0 Leucine Rich Repeat OLF PF02191.14 001261337.2_29624001_2 - 1.6e-74 250.5 0.0 2e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Prefoldin_2 PF01920.18 001261337.2_29624001_2 - 0.011 15.6 2.4 2.3 8.1 0.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.6 001261337.2_29624001_2 - 0.045 13.8 2.3 0.081 13.0 2.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GrpE PF01025.17 001261337.2_29624001_2 - 0.14 11.7 1.0 0.22 11.1 1.0 1.2 1 0 0 1 1 1 0 GrpE FH2 PF02181.21 001261337.2_29624001_2 - 0.25 10.3 0.3 0.35 9.8 0.3 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain CLZ PF16526.3 001261337.2_29624001_2 - 0.31 11.3 4.1 6.8 7.0 0.2 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ERM PF00769.17 001261337.2_29624001_2 - 0.32 10.7 6.3 0.45 10.2 6.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MAD PF05557.11 001261337.2_29624001_2 - 0.38 8.9 4.5 0.54 8.4 4.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein EF-hand_1 PF00036.30 001266662.1_29622001_3 - 9.5e-38 124.8 4.1 1.9e-08 33.1 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001266662.1_29622001_3 - 4.9e-32 110.1 0.2 1.2e-15 57.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.4 001266662.1_29622001_3 - 4.4e-31 106.3 3.5 5.5e-13 48.3 0.0 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.4 001266662.1_29622001_3 - 5.5e-30 101.4 4.6 4.4e-07 29.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001266662.1_29622001_3 - 2.7e-29 98.4 0.2 5.9e-08 31.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.4 001266662.1_29622001_3 - 1.6e-12 47.4 0.0 2.1e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001266662.1_29622001_3 - 1.9e-07 30.9 0.5 0.019 14.8 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001266662.1_29622001_3 - 6.2e-07 29.6 0.0 0.021 15.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.11 001266662.1_29622001_3 - 5.8e-05 22.9 0.7 0.016 15.1 0.1 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB Toprim_2 PF13155.4 001266662.1_29622001_3 - 0.01 16.1 1.5 0.44 10.9 0.2 3.0 1 1 2 3 3 3 0 Toprim-like Caleosin PF05042.11 001266662.1_29622001_3 - 0.014 15.2 1.1 6.7 6.5 0.1 3.0 1 1 3 4 4 4 0 Caleosin related protein EF-hand_11 PF08976.9 001266662.1_29622001_3 - 0.015 16.1 0.0 0.12 13.2 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain p25-alpha PF05517.10 001266662.1_29622001_3 - 0.043 13.9 0.0 16 5.5 0.0 3.0 1 1 3 4 4 4 0 p25-alpha GPHH PF16905.3 001266662.1_29622001_3 - 0.085 12.5 0.0 6.8 6.5 0.0 3.3 3 1 1 4 4 4 0 Voltage-dependent L-type calcium channel, IQ-associated Phage_TAC_12 PF12363.6 001266662.1_29622001_3 - 0.098 13.0 0.3 0.71 10.2 0.1 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Cytochrome_CBB3 PF13442.4 001266662.1_29622001_3 - 0.1 12.8 0.3 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III SurA_N_2 PF13623.4 001266662.1_29622001_3 - 0.1 12.3 0.7 3.8 7.2 0.1 2.4 1 1 1 2 2 2 0 SurA N-terminal domain Dockerin_1 PF00404.16 001266662.1_29622001_3 - 4.9 7.1 15.3 5 7.1 1.8 4.1 4 0 0 4 4 4 0 Dockerin type I repeat PMT PF02366.16 001133054.1_43527001_1 - 4.4e-45 154.1 2.2 5.8e-45 153.7 2.2 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.3 001133054.1_43527001_2 - 2.8e-51 173.8 8.6 4e-51 173.3 8.6 1.2 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.16 001133054.1_43527001_3 - 2.3e-31 109.2 12.0 3.2e-31 108.6 12.0 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.17 001133054.1_43527001_3 - 2e-14 53.7 0.0 3.2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 MIR domain ORC4_C PF14629.4 001285820.1_29524001_1 - 8.2e-52 175.6 4.7 1.3e-51 175.0 4.7 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.4 001285820.1_29524001_1 - 2.2e-12 47.5 0.1 8.2e-12 45.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.27 001285820.1_29524001_1 - 3.5e-10 40.3 0.1 7.9e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 001285820.1_29524001_1 - 2.7e-08 34.0 0.3 1.1e-07 32.1 0.1 2.0 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.16 001285820.1_29524001_1 - 2.4e-07 30.8 1.1 5e-07 29.7 0.2 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.10 001285820.1_29524001_1 - 2.5e-05 24.1 0.9 7.6e-05 22.5 0.9 1.9 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.4 001285820.1_29524001_1 - 4.3e-05 23.8 0.3 0.00037 20.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.4 001285820.1_29524001_1 - 0.00039 20.3 0.7 0.0012 18.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.11 001285820.1_29524001_1 - 0.00061 18.9 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.9 001285820.1_29524001_1 - 0.00066 18.8 0.4 0.003 16.7 0.4 2.0 1 1 0 1 1 1 1 Bacterial TniB protein NB-ARC PF00931.20 001285820.1_29524001_1 - 0.001 18.1 0.1 0.0018 17.2 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain T2SSE PF00437.18 001285820.1_29524001_1 - 0.0015 17.5 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.7 001285820.1_29524001_1 - 0.002 17.3 0.1 0.0031 16.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.7 001285820.1_29524001_1 - 0.0023 17.0 1.1 0.095 11.7 0.1 3.0 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 Mg_chelatase PF01078.19 001285820.1_29524001_1 - 0.021 14.1 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.12 001285820.1_29524001_1 - 0.028 13.5 0.1 0.045 12.8 0.1 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_33 PF13671.4 001285820.1_29524001_1 - 0.03 14.4 0.0 0.085 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.4 001285820.1_29524001_1 - 0.032 14.6 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.25 001285820.1_29524001_1 - 0.041 14.2 1.0 0.24 11.8 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_5 PF07728.12 001285820.1_29524001_1 - 0.052 13.4 0.1 0.16 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.14 001285820.1_29524001_1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.17 001285820.1_29524001_1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.8 001285820.1_29524001_1 - 0.076 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.4 001285820.1_29524001_1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.4 001285820.1_29524001_1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.4 001285820.1_29524001_1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Lys PF00062.18 001246007.1_39522001_1 - 4.1e-31 107.7 0.6 4.9e-31 107.4 0.6 1.1 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.18 001246007.1_39522001_1 - 0.005 16.3 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Prefoldin_2 PF01920.18 001265982.1_29623001_1 - 1.5e-06 28.0 4.1 3.3e-06 26.9 4.1 1.5 1 1 0 1 1 1 1 Prefoldin subunit 7tm_1 PF00001.19 001243140.1_08025001_1 - 6.4e-31 107.4 22.8 1.1e-30 106.7 22.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GnHR_trans PF12369.6 001243140.1_08025001_1 - 3.1e-27 95.0 0.8 5.8e-27 94.2 0.8 1.5 1 0 0 1 1 1 1 Gonadotropin hormone receptor transmembrane region LRR_8 PF13855.4 001243140.1_08025001_1 - 1.1e-18 66.6 16.9 5.5e-06 25.9 0.0 5.4 3 2 3 6 6 6 4 Leucine rich repeat LRR_5 PF13306.4 001243140.1_08025001_1 - 3.9e-14 52.6 0.4 1e-06 28.6 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRRNT PF01462.16 001243140.1_08025001_1 - 1.8e-08 33.7 3.1 1.8e-08 33.7 3.1 2.7 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.5 001243140.1_08025001_1 - 5.3e-07 29.7 20.9 0.078 13.3 5.3 4.9 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001243140.1_08025001_1 - 0.0026 17.1 1.9 0.0026 17.1 1.9 2.6 2 1 0 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.31 001243140.1_08025001_1 - 2.1 9.0 11.0 33 5.4 1.0 6.0 5 0 0 5 5 5 0 Leucine Rich Repeat EGF_CA PF07645.13 001260534.1_29626001_2 - 5.4e-45 151.2 89.0 5.1e-11 42.5 8.5 7.5 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.5 001260534.1_29626001_2 - 8.2e-39 131.0 45.6 1.6e-11 43.8 2.9 7.3 6 0 0 6 6 6 6 Complement Clr-like EGF-like FXa_inhibition PF14670.4 001260534.1_29626001_2 - 1.5e-24 85.9 93.6 3.2e-09 36.8 6.2 8.4 8 1 0 8 8 8 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.5 001260534.1_29626001_2 - 9.2e-13 48.0 63.3 2.7e-06 27.3 4.6 7.6 7 0 0 7 7 7 5 EGF domain hEGF PF12661.5 001260534.1_29626001_2 - 0.00011 22.6 73.8 0.0025 18.3 4.0 8.8 8 1 0 8 8 8 4 Human growth factor-like EGF Plasmod_Pvs28 PF06247.9 001260534.1_29626001_2 - 0.0025 17.9 42.0 0.024 14.8 5.4 5.4 5 0 0 5 5 5 3 Pvs28 EGF domain EGF PF00008.25 001260534.1_29626001_2 - 0.0049 17.0 7.5 0.0049 17.0 7.5 8.1 9 0 0 9 9 9 4 EGF-like domain adh_short PF00106.23 001109356.1_45724001_3 - 1.2e-44 152.0 0.0 1.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001109356.1_45724001_3 - 8.1e-33 113.8 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001109356.1_45724001_3 - 9.7e-13 48.3 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 KR domain PMP22_Claudin PF00822.18 001243444.1_49823001_1 - 4.7e-49 166.3 10.9 6e-49 166.0 10.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001243444.1_49823001_1 - 6.4e-05 22.6 13.9 0.00048 19.8 13.1 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.4 001243444.1_49823001_1 - 0.88 9.8 9.9 5.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) VWA PF00092.26 001082009.1_37927001_1 - 2.1e-27 96.4 0.0 4.3e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.8 001082009.1_37927001_1 - 5e-27 94.2 2.3 1.2e-26 93.0 2.3 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.4 001082009.1_37927001_1 - 1.5e-17 63.8 0.0 3.9e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.4 001082009.1_37927001_1 - 8.1e-13 48.8 0.1 2e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain ITI_HC_C PF06668.10 001082009.1_37927001_1 - 2.8e-06 27.0 0.0 0.002 17.7 0.0 2.5 2 0 0 2 2 2 2 Inter-alpha-trypsin inhibitor heavy chain C-terminus VWA_CoxE PF05762.12 001082009.1_37927001_1 - 7.7e-05 22.0 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.7 001082009.1_37927001_1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus T7SS_ESX_EspC PF10824.6 001082009.1_37927001_1 - 0.3 11.4 2.5 1.6 9.1 0.3 2.6 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm SLC35F PF06027.10 001260513.1_29624001_3 - 1.1e-146 488.0 29.5 1.3e-146 487.7 29.5 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.18 001260513.1_29624001_3 - 3.2e-10 40.2 33.0 1.5e-07 31.5 16.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.8 001260513.1_29624001_3 - 1.5e-08 33.8 5.7 1.5e-08 33.8 5.7 2.0 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Spo7 PF03907.11 001260513.1_29624001_3 - 0.58 9.5 2.2 1.2 8.4 2.2 1.5 1 0 0 1 1 1 0 Spo7-like protein XTBD PF11952.6 001261581.1_29625001_2 - 5.6e-31 106.0 0.0 1.4e-29 101.5 0.0 2.3 2 0 0 2 2 2 1 XRN-Two Binding Domain, XTBD Ish1 PF10281.7 001261581.1_29625001_2 - 0.038 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Spot_14 PF07084.10 001256365.1_49822001_1 - 1.2e-65 220.2 0.0 1.3e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Erf4 PF10256.7 001260720.1_29622001_1 - 1.7e-33 115.0 0.0 2.1e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Serglycin PF04360.10 001260720.1_29622001_1 - 7.2 6.4 10.1 24 4.7 9.7 1.9 1 1 0 2 2 2 0 Serglycin Laminin_N PF00055.15 001266055.1_29627001_1 - 9.1e-68 228.2 0.8 9.1e-68 228.2 0.8 2.0 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.22 001266055.1_29627001_1 - 2.7e-25 88.1 67.0 2.4e-10 40.2 8.7 6.5 4 1 1 5 5 5 3 Laminin EGF domain NTR PF01759.19 001266055.1_29627001_1 - 5.2e-22 77.5 1.4 8.5e-22 76.9 0.1 2.0 2 0 0 2 2 2 1 UNC-6/NTR/C345C module F5_F8_type_C PF00754.23 001266055.1_29627001_1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain MIP PF00230.18 001266495.2_29623001_2 - 9.4e-07 28.6 9.4 3.6e-06 26.7 5.0 2.1 1 1 1 2 2 2 2 Major intrinsic protein WD40 PF00400.30 001133197.2_43527001_1 - 2.4e-14 53.3 3.2 3.6e-05 24.3 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001133197.2_43527001_1 - 0.00019 21.5 0.1 0.059 13.6 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 001133197.2_43527001_1 - 0.039 12.4 0.3 0.22 10.0 0.1 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.10 001133197.2_43527001_1 - 0.17 11.7 1.1 31 4.5 0.2 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.30 001133197.2_43527001_3 - 1.6e-16 60.3 5.6 2.2e-07 31.3 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat SOCS_box PF07525.14 001133197.2_43527001_3 - 9e-11 41.8 2.6 1.1e-10 41.6 0.8 2.1 2 0 0 2 2 2 1 SOCS box Ge1_WD40 PF16529.3 001133197.2_43527001_3 - 5.8e-07 28.7 0.1 0.21 10.4 0.1 3.1 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.5 001133197.2_43527001_3 - 0.00044 20.3 0.0 0.4 10.9 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase PF00102.25 001082750.1_37929001_3 - 2.3e-83 279.3 1.7 4.3e-83 278.3 1.7 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.19 001082750.1_37929001_3 - 2.6e-25 88.4 15.2 7e-07 29.4 0.8 6.9 7 0 0 7 7 7 4 Fibronectin type III domain Y_phosphatase3 PF13350.4 001082750.1_37929001_3 - 5.9e-05 23.0 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.18 001082750.1_37929001_3 - 0.00011 21.8 0.0 0.00042 20.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.4 001082750.1_37929001_3 - 0.0011 19.0 0.1 0.0029 17.6 0.1 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate Pur_ac_phosph_N PF16656.3 001082750.1_37929001_3 - 0.004 17.6 3.4 3.6 8.1 0.3 4.1 3 1 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain MgtE PF01769.14 001261146.1_29629001_2 - 1.8e-54 183.2 18.9 7.7e-30 103.7 2.7 2.6 2 0 0 2 2 2 2 Divalent cation transporter Ribosomal_60s PF00428.17 001261146.1_29629001_3 - 1.9 9.0 8.1 4.4 7.8 8.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein IL17 PF06083.9 001261287.1_29622001_1 - 2.5e-28 98.2 2.2 4e-28 97.6 2.2 1.3 1 0 0 1 1 1 1 Interleukin-17 MARVEL PF01284.21 001284917.1_29523001_1 - 3.3e-06 27.1 13.0 4.8e-06 26.5 13.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain GWT1 PF06423.10 001284917.1_29523001_1 - 0.0049 16.9 1.1 0.15 12.1 0.3 2.3 2 0 0 2 2 2 1 GWT1 Ctr PF04145.13 001284917.1_29523001_1 - 0.037 14.5 0.0 0.19 12.2 0.0 2.1 1 1 0 1 1 1 0 Ctr copper transporter family OATP PF03137.18 001284917.1_29523001_1 - 0.86 7.7 4.8 2.2 6.3 4.9 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RNA_polI_A34 PF08208.9 001284917.1_29523001_2 - 0.0048 16.9 26.2 0.0048 16.9 26.2 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Aa_trans PF01490.16 001266098.1_29624001_2 - 4.4e-79 265.9 38.6 5.3e-79 265.7 38.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.19 001266098.1_29624001_2 - 0.00062 19.4 9.9 0.00062 19.4 9.9 2.7 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cyclin_C_2 PF16899.3 001266446.1_29623001_3 - 5.8e-27 93.9 0.8 4e-25 88.0 0.2 2.6 3 0 0 3 3 3 1 Cyclin C-terminal domain Cyclin_N PF00134.21 001266446.1_29623001_3 - 5.9e-09 35.7 0.2 1.3e-08 34.6 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001266446.1_29623001_3 - 0.03 14.3 0.2 0.4 10.7 0.1 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain Adap_comp_sub PF00928.19 001243644.1_49824001_3 - 1.6e-81 273.4 0.1 2.1e-81 273.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.18 001243644.1_49824001_3 - 1.7e-05 24.6 0.5 2.8e-05 23.9 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.7 001243644.1_49824001_3 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Vasohibin PF14822.4 001261805.1_29629001_2 - 6.8e-118 392.2 0.0 8.8e-118 391.8 0.0 1.1 1 0 0 1 1 1 1 Vasohibin Interferon PF00143.17 001245021.1_22422001_1 - 1.3e-57 194.3 0.2 1.5e-57 194.2 0.2 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Thymosin PF01290.18 001141991.1_49822001_1 - 4.1e-20 71.1 10.8 4.1e-20 71.1 10.8 2.0 2 0 0 2 2 2 1 Thymosin beta-4 family GRAM PF02893.18 001258099.2_29624001_2 - 7.7e-15 54.6 0.0 2e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 GRAM domain Vps36_ESCRT-II PF11605.6 001258099.2_29624001_2 - 0.00052 20.0 0.0 0.00083 19.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 CH PF00307.29 001266904.1_29623001_2 - 1.4e-20 73.4 0.0 1.9e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.16 001266904.1_29623001_2 - 6.7e-14 51.1 5.9 1.3e-13 50.1 5.9 1.5 1 0 0 1 1 1 1 Calponin family repeat Lys PF00062.18 001285551.1_09022001_2 - 8.2e-31 106.7 0.6 1e-30 106.4 0.6 1.1 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.18 001285551.1_09022001_2 - 0.0057 16.2 0.0 0.008 15.7 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain ICAM_N PF03921.12 001145379.2_49823001_2 - 6.1e-25 86.6 0.0 1.7e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Intercellular adhesion molecule (ICAM), N-terminal domain C2-set_2 PF08205.10 001145379.2_49823001_2 - 0.012 15.5 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Mnd1 PF03962.13 001260703.1_29623001_2 - 0.0084 15.9 2.5 0.0084 15.9 2.5 2.3 2 1 0 2 2 2 1 Mnd1 family AMP-binding_C_2 PF14535.4 001260703.1_29623001_2 - 0.16 12.2 2.4 2.2 8.5 2.4 2.4 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF3544 PF12064.6 001133575.1_43528001_1 - 1.4e-102 342.2 19.6 1.4e-102 342.2 19.6 5.2 4 2 0 4 4 4 1 Domain of unknown function (DUF3544) Bromodomain PF00439.23 001133575.1_43528001_1 - 9.2e-16 57.6 0.0 2.6e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.15 001133575.1_43528001_1 - 1.9e-06 28.1 0.3 1.9e-06 28.1 0.3 3.3 2 0 0 2 2 2 1 PWWP domain PHD PF00628.27 001133575.1_43528001_1 - 0.0002 21.1 11.7 0.0002 21.1 11.7 3.5 3 0 0 3 3 3 1 PHD-finger zf-MYND PF01753.16 001133575.1_43528001_1 - 0.0018 18.2 17.1 0.0018 18.2 17.1 3.8 3 1 0 3 3 3 1 MYND finger DUF1640 PF07798.9 001133575.1_43528001_1 - 0.0026 17.7 6.5 0.0026 17.7 6.5 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1640) WD40 PF00400.30 001261284.1_29624001_1 - 1.5e-34 117.3 16.9 1.1e-07 32.3 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001261284.1_29624001_1 - 8.5e-14 51.5 0.3 0.0094 16.1 0.0 6.3 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain SOCS_box PF07525.14 001261284.1_29624001_1 - 7.8e-11 42.0 2.3 9.5e-11 41.7 0.5 2.1 2 0 0 2 2 2 1 SOCS box Ge1_WD40 PF16529.3 001261284.1_29624001_1 - 9.8e-10 37.8 0.3 0.11 11.4 0.1 4.5 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.9 001261284.1_29624001_1 - 6e-05 22.9 0.0 0.029 14.1 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.4 001261284.1_29624001_1 - 0.00074 18.8 0.1 3 7.0 0.0 3.5 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.6 001261284.1_29624001_1 - 0.0067 15.0 0.3 0.11 10.9 0.1 2.4 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.10 001261284.1_29624001_1 - 0.033 14.0 5.1 16 5.5 0.2 4.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.4 001261284.1_29624001_1 - 0.16 12.4 2.7 2.5 8.5 0.2 3.5 4 0 0 4 4 4 0 PQQ-like domain Clat_adaptor_s PF01217.18 001261143.2_29622001_2 - 9.8e-62 207.0 8.5 1.1e-61 206.7 8.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ank_2 PF12796.5 001257583.1_29625001_1 - 2.9e-29 101.3 4.0 9.9e-14 51.6 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001257583.1_29625001_1 - 9.5e-27 92.9 5.4 3.9e-09 36.7 0.1 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.4 001257583.1_29625001_1 - 8.2e-25 86.4 14.3 4.9e-09 36.2 2.4 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.28 001257583.1_29625001_1 - 7.3e-23 79.8 12.6 6.7e-06 26.2 1.5 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.4 001257583.1_29625001_1 - 8.3e-20 68.7 7.6 0.0006 19.9 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Pkinase PF00069.23 001044621.3_49823001_2 - 3.9e-72 242.7 0.0 4.5e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001044621.3_49823001_2 - 3.6e-33 114.8 0.0 4.7e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001044621.3_49823001_2 - 0.012 14.8 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.9 001044621.3_49823001_2 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.21 001044621.3_49823001_2 - 0.058 13.2 0.1 0.093 12.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fz PF01392.20 001243406.1_49823001_1 - 6.7e-27 94.3 2.2 1.5e-26 93.2 2.2 1.6 1 0 0 1 1 1 1 Fz domain NTR PF01759.19 001243406.1_49823001_1 - 2.4e-12 46.4 0.1 3.7e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module RRM_1 PF00076.20 001145184.2_39521001_1 - 5.7e-13 48.4 0.0 8e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001145184.2_39521001_1 - 0.025 14.4 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.11 001145184.2_39521001_1 - 0.034 14.0 0.0 0.061 13.2 0.0 1.4 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-RING_UBOX PF13445.4 001244690.1_49825001_1 - 7.8e-10 38.5 3.9 2.1e-09 37.1 3.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.4 001244690.1_49825001_1 - 3.5e-08 33.0 2.3 3.5e-08 33.0 2.3 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001244690.1_49825001_1 - 5.3e-08 32.5 2.9 5.3e-08 32.5 2.9 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.22 001244690.1_49825001_1 - 6.4e-07 29.3 6.5 6.4e-07 29.3 6.5 3.6 4 0 0 4 4 4 1 B-box zinc finger zf-RING_2 PF13639.4 001244690.1_49825001_1 - 7e-07 29.3 4.6 7e-07 29.3 4.6 2.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.4 001244690.1_49825001_1 - 1.8e-06 27.7 4.7 1.8e-06 27.7 4.7 2.5 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001244690.1_49825001_1 - 1.5e-05 24.6 7.1 1.5e-05 24.6 7.1 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.4 001244690.1_49825001_1 - 2.1e-05 24.4 6.3 2.1e-05 24.4 6.3 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.4 001244690.1_49825001_1 - 3.8e-05 23.3 0.4 3.8e-05 23.3 0.4 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein UvrD_C PF13361.4 001244690.1_49825001_1 - 0.016 14.4 4.9 0.025 13.8 4.9 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF1076 PF06416.10 001244690.1_49825001_1 - 0.036 13.8 0.7 0.32 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1076) FliS PF02561.12 001244690.1_49825001_1 - 0.17 12.0 1.8 0.82 9.8 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein FliS DUF1664 PF07889.10 001244690.1_49825001_1 - 0.36 10.7 3.9 0.57 10.0 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_11 PF17123.3 001244690.1_49825001_1 - 3.4 7.3 9.8 2.3 7.9 6.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger Mito_carr PF00153.25 001244793.1_49823001_3 - 4.9e-68 225.0 1.3 3e-24 84.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CSD PF00313.20 001261063.2_29623001_3 - 1.5e-11 43.8 0.0 2.2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.9 001261063.2_29623001_3 - 0.046 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain CH PF00307.29 001265900.1_29623001_2 - 6.1e-23 81.0 0.0 1.2e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.16 001265900.1_29623001_2 - 1.7e-13 49.8 6.1 3.7e-13 48.7 6.1 1.6 1 0 0 1 1 1 1 Calponin family repeat CDC24 PF06395.9 001265900.1_29623001_2 - 0.00094 19.3 0.3 0.0029 17.7 0.0 1.7 2 0 0 2 2 2 1 CDC24 Calponin Interferon PF00143.17 001031830.1_22422001_1 - 5.1e-57 192.4 0.2 5.7e-57 192.2 0.2 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain DUF4604 PF15377.4 001082155.2_37924001_1 - 0.0084 16.4 12.2 0.012 16.0 12.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF4604 PF15377.4 001082155.2_37924001_2 - 0.0024 18.2 10.1 0.0036 17.6 10.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) MARVEL PF01284.21 001266554.1_29629001_1 - 3.5e-29 101.5 5.0 5.5e-29 100.9 5.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain PIP49_C PF12260.6 001266885.1_29626001_3 - 3.9e-66 222.1 0.2 6.6e-66 221.4 0.2 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.4 001266885.1_29626001_3 - 3.1e-59 199.2 0.3 3.1e-59 199.2 0.3 1.7 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 zf-HIT PF04438.14 001199228.2_37922001_1 - 3.6e-08 33.0 12.8 3.6e-08 33.0 12.8 1.7 1 1 0 1 1 1 1 HIT zinc finger Pkinase PF00069.23 001257780.1_29629001_2 - 1.2e-62 211.6 0.0 1.5e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001257780.1_29629001_2 - 6.3e-47 159.9 0.0 8.9e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.6 001257780.1_29629001_2 - 2e-13 49.9 0.0 3.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C terminal Kinase-like PF14531.4 001257780.1_29629001_2 - 0.0022 17.2 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RAM PF15320.4 001265849.1_29622001_1 - 1.3e-22 80.1 11.5 1.9e-22 79.5 11.5 1.3 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein 2OG-FeII_Oxy_3 PF13640.4 001261553.1_29623001_3 - 7.6e-10 39.4 0.1 1.4e-09 38.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.7 001261553.1_29623001_3 - 0.059 12.8 0.2 0.5 9.8 0.2 2.2 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA TGFb_propeptide PF00688.16 001266518.1_29624001_3 - 1.4e-34 119.8 0.0 1.9e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 001266518.1_29624001_3 - 1.3e-23 83.8 1.4 1.3e-23 83.8 1.4 2.1 2 0 0 2 2 2 1 Transforming growth factor beta like domain SPEG_u2 PF16650.3 001266518.1_29624001_3 - 1.1 9.3 4.4 0.22 11.6 0.5 1.7 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein ATG11 PF10377.7 001266144.1_29629001_1 - 3.2e-25 88.5 0.0 3.2e-25 88.5 0.0 4.3 4 1 1 5 5 5 1 Autophagy-related protein 11 NPBW PF15180.4 001266144.1_29629001_1 - 1.4 8.6 7.1 0.35 10.6 0.7 3.3 3 0 0 3 3 3 0 Neuropeptides B and W AdoHcyase PF05221.15 001258058.1_29628001_2 - 2.9e-120 400.8 0.0 4.6e-64 216.3 0.5 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.19 001258058.1_29628001_2 - 1.4e-81 272.1 2.5 2.1e-81 271.6 2.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.17 001258058.1_29628001_2 - 7.8e-09 35.0 0.1 1.4e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.10 001258058.1_29628001_2 - 0.0002 20.8 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.17 001258058.1_29628001_2 - 0.00094 18.4 1.1 0.0024 17.1 1.1 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.18 001258058.1_29628001_2 - 0.003 17.5 0.1 0.0064 16.4 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.19 001258058.1_29628001_2 - 0.0064 15.7 0.6 0.014 14.6 0.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.4 001258058.1_29628001_2 - 0.015 15.6 0.9 0.036 14.4 0.9 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.16 001258058.1_29628001_2 - 0.027 14.6 0.2 0.062 13.4 0.2 1.6 1 1 0 1 1 1 0 TrkA-N domain Big_3_5 PF16640.3 001258058.1_29628001_2 - 0.087 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) SR-25 PF10500.7 001258058.1_29628001_2 - 0.52 9.7 7.9 1 8.8 7.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GST_N_3 PF13417.4 001289962.1_29622001_2 - 4.2e-18 65.4 0.1 8.7e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001289962.1_29622001_2 - 1.5e-12 47.6 0.1 3e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001289962.1_29622001_2 - 2.4e-12 46.9 0.1 4.6e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001289962.1_29622001_2 - 0.00012 21.8 0.4 0.00024 20.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 001289962.1_29622001_2 - 0.00016 21.7 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.4 001289962.1_29622001_2 - 0.047 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001289962.1_29622001_2 - 0.063 13.4 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-DHHC PF01529.18 001163604.1_39522001_1 - 8.6e-36 122.9 14.2 8.6e-36 122.9 14.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4761 PF15958.3 001163604.1_39522001_1 - 0.12 12.4 0.0 3.7 7.6 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4761) TRIQK PF15168.4 001163604.1_39522001_1 - 1.6 8.5 4.0 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Fibrinogen_C PF00147.16 001142828.2_49823001_1 - 1.3e-71 240.8 4.8 1.7e-71 240.4 4.8 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain IncA PF04156.12 001142828.2_49823001_1 - 0.0058 16.3 0.1 0.046 13.4 0.4 2.0 2 0 0 2 2 2 1 IncA protein COG2 PF06148.9 001142828.2_49823001_1 - 0.11 12.4 1.8 0.2 11.6 1.8 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 PI3Ka PF00613.18 001260668.1_29628001_3 - 1.2e-68 230.0 1.6 2.3e-68 229.1 1.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.25 001260668.1_29628001_3 - 1.5e-57 195.2 1.2 7.9e-57 192.8 1.2 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.16 001260668.1_29628001_3 - 1.3e-38 131.3 1.2 1.6e-36 124.5 0.5 2.8 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.22 001260668.1_29628001_3 - 4.9e-34 117.2 0.0 1.1e-33 116.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_p85B PF02192.14 001260668.1_29628001_3 - 2.1e-30 104.1 0.3 4.9e-30 102.9 0.3 1.7 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain DUF2321 PF10083.7 001260668.1_29628001_3 - 0.025 14.1 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) ASC PF00858.22 001260668.1_29628001_3 - 0.068 12.0 0.4 0.12 11.2 0.4 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF4135 PF13575.4 001260668.1_29628001_3 - 0.073 12.2 0.0 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) GST_N PF02798.18 001257634.1_29623001_1 - 6.6e-13 48.7 0.0 2.1e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.4 001257634.1_29623001_1 - 9.1e-11 41.9 0.0 1.8e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001257634.1_29623001_1 - 1.3e-07 31.6 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.4 001257634.1_29623001_1 - 5.3e-07 29.7 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001257634.1_29623001_1 - 5.4e-06 26.1 0.2 1.3e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001257634.1_29623001_1 - 0.00054 20.0 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Oxidored_nitro PF00148.17 001257634.1_29623001_1 - 0.068 11.8 0.0 0.093 11.3 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase PIGA PF08288.10 001260603.1_29628001_2 - 8.9e-43 144.7 2.0 1.9e-42 143.6 2.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.4 001260603.1_29628001_2 - 1.1e-24 87.2 0.1 1.5e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.18 001260603.1_29628001_2 - 6e-21 74.7 0.0 9.8e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001260603.1_29628001_2 - 1.9e-19 70.3 0.0 4e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.4 001260603.1_29628001_2 - 3.1e-09 37.3 0.0 4.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.4 001260603.1_29628001_2 - 0.0094 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.9 001260603.1_29628001_2 - 0.089 12.3 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Starch synthase catalytic domain PROL5-SMR PF15621.4 001265986.1_29628001_1 - 9e-05 22.8 0.7 0.00017 21.9 0.7 1.4 1 0 0 1 1 1 1 Proline-rich submaxillary gland androgen-regulated family C2 PF00168.28 001265986.1_29628001_3 - 8.7e-43 144.7 0.0 3.5e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain Interferon PF00143.17 001031832.1_22422001_1 - 4.2e-58 195.9 0.1 4.8e-58 195.7 0.1 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain TGF_beta PF00019.18 001285581.1_09023001_1 - 1.3e-31 109.4 1.6 2.8e-31 108.4 1.6 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 001285581.1_09023001_1 - 1.9e-09 37.5 0.5 1.4e-08 34.7 0.5 2.2 1 1 0 1 1 1 1 TGF-beta propeptide Parathyroid PF01279.15 213916.2_49823001_1 - 7.4e-33 113.3 0.6 7.4e-33 113.3 0.6 1.8 2 0 0 2 2 2 1 Parathyroid hormone family Aa_trans PF01490.16 001243482.1_49824001_1 - 7.4e-91 304.7 33.0 8.7e-91 304.5 33.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CNDH2_C PF16858.3 001206363.1_49825001_3 - 1.3e-91 307.3 0.4 1.7e-91 306.9 0.4 1.2 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.9 001206363.1_49825001_3 - 8.1e-46 154.7 0.1 1.4e-45 154.0 0.1 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_M PF16869.3 001206363.1_49825001_3 - 3.7e-20 73.0 0.1 1.8e-19 70.7 0.0 2.3 3 0 0 3 3 3 1 PF16858 Mito_carr PF00153.25 001260849.1_29626001_3 - 9.4e-64 211.3 0.2 4.8e-21 74.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.25 001244966.1_49823001_2 - 4.2e-59 196.4 3.6 1.1e-19 70.0 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Trypsin PF00089.24 001166195.1_39524001_1 - 2.4e-67 226.8 0.0 3.7e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.16 001166195.1_39524001_1 - 8e-49 163.7 8.0 3.6e-26 91.2 1.6 2.5 2 0 0 2 2 2 2 Kringle domain Thrombin_light PF09396.8 001166195.1_39524001_1 - 2.9e-25 87.6 2.8 5.8e-25 86.7 2.8 1.5 1 0 0 1 1 1 1 Thrombin light chain Gla PF00594.18 001166195.1_39524001_1 - 1.1e-17 63.8 2.6 1.1e-17 63.8 2.6 1.9 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Trypsin_2 PF13365.4 001166195.1_39524001_1 - 0.00077 20.2 0.0 0.0032 18.2 0.0 2.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001166195.1_39524001_1 - 0.00098 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) IP_trans PF02121.16 001266329.1_29626001_3 - 1.7e-117 391.2 1.5 2.8e-117 390.5 1.5 1.3 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein SH3_9 PF14604.4 001261286.1_29627001_3 - 2.5e-17 62.3 0.0 4.9e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain His_Phos_1 PF00300.20 001261286.1_29627001_3 - 1.6e-16 60.5 0.0 3.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UBA PF00627.29 001261286.1_29627001_3 - 6.6e-07 29.0 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain SH3_1 PF00018.26 001261286.1_29627001_3 - 2.2e-05 23.8 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain 2_5_RNA_ligase2 PF13563.4 001261286.1_29627001_3 - 4.7e-05 23.2 0.4 0.00011 22.0 0.3 1.6 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.14 001261286.1_29627001_3 - 0.00099 19.1 0.1 1.4 9.1 0.1 2.6 2 0 0 2 2 2 2 LigT like Phosphoesterase DSPc PF00782.18 001261286.1_29627001_3 - 0.11 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Aldedh PF00171.20 001132369.2_43527001_2 - 6.8e-99 331.3 0.0 8.6e-99 331.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OATP PF03137.18 001132369.2_43527001_2 - 0.013 13.7 1.5 0.018 13.3 1.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Connexin PF00029.17 001132369.2_43527001_2 - 3.4 7.2 11.1 5 6.7 11.1 1.2 1 0 0 1 1 1 0 Connexin Pentaxin PF00354.15 001266044.1_29629001_1 - 6e-33 114.0 0.0 9.5e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.4 001266044.1_29629001_1 - 2.5e-15 56.8 0.0 3.7e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.22 001266044.1_29629001_1 - 0.13 12.8 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain CLZ PF16526.3 001266044.1_29629001_1 - 1 9.6 4.2 26 5.1 0.2 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RabGAP-TBC PF00566.16 001258153.1_29629001_3 - 1.8e-26 93.0 10.3 3.2e-25 88.9 10.3 2.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3452 PF11934.6 001258153.1_29629001_3 - 0.0063 15.9 0.1 0.014 14.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) Mito_carr PF00153.25 001280692.1_39523001_1 - 4.7e-65 215.4 0.2 9.6e-22 76.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NHase_alpha PF02979.14 001280692.1_39523001_1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain SLAIN PF15301.4 001266145.1_29627001_1 - 8e-170 565.6 35.7 1.3e-169 565.0 35.7 1.3 1 0 0 1 1 1 1 SLAIN motif-containing family GIT_CC PF16559.3 001266145.1_29627001_1 - 0.079 12.9 4.2 0.31 11.0 3.6 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.19 001266145.1_29627001_1 - 0.33 11.0 4.4 0.11 12.4 1.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor SIS PF01380.20 001194979.1_49826001_2 - 2.7e-70 234.2 0.1 4.3e-36 123.5 0.0 2.2 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.4 001194979.1_49826001_2 - 6.7e-17 61.8 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.4 001194979.1_49826001_2 - 2.6e-12 46.6 0.0 6.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.4 001194979.1_49826001_2 - 3.2e-05 22.9 0.0 5.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.19 001194979.1_49826001_2 - 0.0048 15.5 0.0 0.0094 14.6 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.4 001194979.1_49826001_2 - 0.039 13.9 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 SIS domain RTP801_C PF07809.9 001257796.1_29624001_1 - 1e-36 125.5 0.0 1.4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 RTP801 C-terminal region MORN PF02493.18 001261095.1_29626001_3 - 1.1e-27 94.1 63.9 3.5e-06 26.5 1.2 8.9 9 0 0 9 9 9 8 MORN repeat Alanine_zipper PF11839.6 001261095.1_29626001_3 - 0.11 12.6 12.5 0.2 11.8 12.5 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein PH PF00169.27 001244817.1_49826001_2 - 3.7e-22 78.7 0.0 2.1e-10 40.9 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.4 001244817.1_49826001_2 - 4.8e-05 23.6 1.2 0.057 13.7 0.0 3.5 2 1 0 2 2 2 2 Pleckstrin homology domain CENP-F_leu_zip PF10473.7 001244817.1_49826001_2 - 0.0086 16.0 8.3 0.022 14.6 8.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PH_9 PF15410.4 001244817.1_49826001_2 - 0.063 13.5 0.4 11 6.3 0.0 3.7 2 2 0 2 2 2 0 Pleckstrin homology domain UPF0449 PF15136.4 001244817.1_49826001_2 - 0.22 11.9 2.8 0.76 10.1 2.8 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF342 PF03961.11 001244817.1_49826001_2 - 0.46 8.9 2.6 0.7 8.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.10 001244817.1_49826001_2 - 2 7.6 8.4 3.6 6.8 8.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 KRTAP PF11759.6 001171267.1_37921001_1 - 0.00012 22.4 92.4 9 6.8 92.4 2.5 1 1 0 1 1 1 1 Keratin-associated matrix Ras PF00071.20 001197063.2_37923001_1 - 1e-50 171.4 0.0 1.3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001197063.2_37923001_1 - 5.2e-18 65.3 0.0 7.4e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001197063.2_37923001_1 - 2.5e-10 39.9 0.0 3.9e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.15 001197063.2_37923001_1 - 0.00042 20.0 0.5 0.0025 17.5 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.25 001197063.2_37923001_1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001197063.2_37923001_1 - 0.018 14.8 0.0 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Acyl-CoA_dh_1 PF00441.22 001167635.1_49823001_1 - 6.4e-39 133.4 0.0 1.1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.14 001167635.1_49823001_1 - 5.7e-38 129.9 0.0 1e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.17 001167635.1_49823001_1 - 1.2e-25 89.4 0.0 2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.9 001167635.1_49823001_1 - 4.7e-09 36.5 0.0 8.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ANAPC4 PF12896.5 001266920.1_29626001_2 - 6.2e-58 195.5 8.8 1e-57 194.8 8.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.5 001266920.1_29626001_2 - 4.5e-26 90.9 0.0 1e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Stathmin PF00836.17 001265775.1_29622001_3 - 8.1e-57 190.9 24.2 1.3e-56 190.2 24.2 1.3 1 0 0 1 1 1 1 Stathmin family Exonuc_VII_L PF02601.13 001265775.1_29622001_3 - 0.25 10.7 5.5 0.28 10.6 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP1G1_PLM_MAT8 PF02038.14 001260855.1_29622001_1 - 2.4e-26 90.7 0.1 3.6e-26 90.1 0.1 1.3 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family TOH_N PF12549.6 001260855.1_29622001_1 - 0.023 14.4 2.8 0.023 14.4 2.8 2.3 1 1 1 2 2 2 0 Tyrosine hydroxylase N terminal Glycophorin_A PF01102.16 001260855.1_29622001_1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A Hormone_recep PF00104.28 001246280.1_39523001_1 - 1.3e-33 116.2 4.7 2e-33 115.6 4.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001246280.1_39523001_1 - 2.4e-32 111.1 12.0 4.1e-32 110.3 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RabGAP-TBC PF00566.16 001266296.1_29625001_1 - 5.5e-40 137.2 0.0 2.5e-39 135.0 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain LBP_BPI_CETP PF01273.23 001243263.1_29625001_1 - 1.3e-27 96.3 0.5 4.5e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.15 001243263.1_29625001_1 - 1.2e-26 93.5 0.9 3e-26 92.2 0.3 1.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain zf-met PF12874.5 001131507.1_43529001_2 - 2.2e-05 24.5 0.9 6.5e-05 23.1 0.9 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CALM_bind PF16025.3 001243946.1_49824001_3 - 3.1 8.2 6.9 1 9.7 3.8 1.7 1 1 1 2 2 2 0 Calcium-dependent calmodulin binding PX PF00787.22 001257708.1_29622001_1 - 1.4e-14 53.9 0.1 2.2e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 PX domain 3HCDH_N PF02737.16 001266898.1_29623001_1 - 1.7e-50 171.3 0.0 2.2e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.20 001266898.1_29623001_1 - 2.2e-16 60.1 0.0 3.5e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.13 001266898.1_29623001_1 - 0.00052 20.1 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.12 001266898.1_29623001_1 - 0.0062 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.17 001266898.1_29623001_1 - 0.0068 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.21 001266898.1_29623001_1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.21 001266898.1_29623001_1 - 0.054 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.19 001266898.1_29623001_1 - 0.078 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.14 001266898.1_29623001_1 - 0.1 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.23 001266898.1_29623001_1 - 0.13 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Mo25 PF08569.9 001267016.1_29628001_3 - 1.4e-141 471.4 16.5 1.8e-141 471.1 16.5 1.1 1 0 0 1 1 1 1 Mo25-like C2 PF00168.28 001261271.1_29626001_2 - 6.6e-13 48.7 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain CUE PF02845.14 001261271.1_29626001_2 - 7.8e-13 47.7 0.1 1.2e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 CUE domain UBA PF00627.29 001261271.1_29626001_2 - 0.099 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Sugar_tr PF00083.22 001265660.1_29625001_1 - 1.7e-17 63.3 4.4 2.6e-17 62.7 4.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001265660.1_29625001_1 - 2.8e-15 56.0 29.7 6.5e-08 31.7 10.5 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.11 001265660.1_29625001_1 - 0.0024 16.2 3.9 0.047 12.0 0.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.23 001284023.1_29525001_2 - 1.1e-68 231.3 0.0 1.5e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.16 001284023.1_29525001_2 - 2.1e-42 143.0 0.8 3.2e-21 75.1 0.3 2.5 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.15 001284023.1_29525001_2 - 2.7e-39 134.9 0.0 4.2e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001284023.1_29525001_2 - 5.6e-10 38.9 0.0 3.5e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.21 001284023.1_29525001_2 - 0.02 14.7 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family I-set PF07679.14 001244551.1_49825001_3 - 3.4e-14 52.5 0.0 4.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 001244551.1_49825001_3 - 5.1e-12 46.1 0.0 8.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.16 001244551.1_49825001_3 - 5.9e-08 33.1 20.6 5.9e-08 33.1 20.6 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Ig_2 PF13895.4 001244551.1_49825001_3 - 4.9e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Kazal_1 PF00050.19 001244551.1_49825001_3 - 2e-05 24.4 0.1 4.1e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain ig PF00047.23 001244551.1_49825001_3 - 3.4e-05 23.8 0.0 8.1e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.13 001244551.1_49825001_3 - 0.0001 22.3 0.7 0.0001 22.3 0.7 1.8 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.15 001244551.1_49825001_3 - 0.00067 19.7 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain HAT_KAT11 PF08214.9 001260715.1_29629001_1 - 1e-68 232.1 0.5 1e-68 232.1 0.5 1.8 2 0 0 2 2 2 1 Histone acetylation protein KIX PF02172.14 001260715.1_29629001_1 - 3.9e-39 132.7 0.4 7.9e-39 131.7 0.4 1.5 1 0 0 1 1 1 1 KIX domain Creb_binding PF09030.8 001260715.1_29629001_1 - 9.6e-34 116.2 16.2 9.6e-34 116.2 16.2 11.5 8 2 2 10 10 10 1 Creb binding zf-TAZ PF02135.14 001260715.1_29629001_1 - 3e-28 98.0 71.7 6.6e-19 68.0 20.6 3.6 3 0 0 3 3 3 2 TAZ zinc finger DUF902 PF06001.11 001260715.1_29629001_1 - 8.1e-22 77.3 9.1 8.1e-22 77.3 9.1 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.23 001260715.1_29629001_1 - 9.1e-17 60.8 0.1 2.3e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.15 001260715.1_29629001_1 - 2.7e-15 55.8 14.0 2.7e-15 55.8 14.0 3.1 3 0 0 3 3 3 1 Zinc finger, ZZ type KIX_2 PF16987.3 001260715.1_29629001_1 - 5.1e-05 23.0 0.1 5.1e-05 23.0 0.1 2.5 2 0 0 2 2 2 1 KIX domain Npa1 PF11707.6 001260715.1_29629001_1 - 0.0052 16.1 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal EPL1 PF10513.7 001260715.1_29629001_1 - 5.1 7.3 20.3 5.1 7.3 4.5 3.9 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF4174 PF13778.4 001135656.1_39723001_1 - 8.4e-34 116.4 0.3 1.1e-33 116.0 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) HYR PF02494.14 001135656.1_39723001_1 - 4.4e-29 100.5 0.0 7.4e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 HYR domain Sushi PF00084.18 001135656.1_39723001_1 - 2.9e-23 82.1 25.4 3.9e-10 40.1 7.2 3.6 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) zf-C2H2 PF00096.24 033218.1_32929120_3 - 4.3e-36 121.2 123.6 0.00013 22.1 2.6 15.8 15 0 0 15 15 15 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 033218.1_32929120_3 - 6.8e-33 110.4 116.9 0.00067 20.1 1.0 16.1 15 0 0 15 15 15 14 C2H2-type zinc finger zf-H2C2_2 PF13465.4 033218.1_32929120_3 - 8.8e-19 66.9 112.7 1.1e-07 31.9 1.1 18.1 18 1 0 18 18 18 4 Zinc-finger double domain zf-C2H2_6 PF13912.4 033218.1_32929120_3 - 5.2e-09 35.7 94.3 8.6e-06 25.4 0.3 14.2 15 0 0 15 15 15 6 C2H2-type zinc finger zf-H2C2_5 PF13909.4 033218.1_32929120_3 - 5.3e-07 29.1 0.0 5.3e-07 29.1 0.0 10.2 11 0 0 11 11 11 4 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.3 033218.1_32929120_3 - 0.0016 18.6 39.0 0.013 15.7 1.1 5.7 5 0 0 5 5 5 3 C2H2-type zinc ribbon FYDLN_acid PF09538.8 033218.1_32929120_3 - 0.0058 17.2 5.8 0.0058 17.2 5.8 6.8 5 3 1 6 6 6 1 Protein of unknown function (FYDLN_acid) zf-met PF12874.5 033218.1_32929120_3 - 0.55 10.6 84.1 0.029 14.6 0.9 13.0 14 0 0 14 14 14 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.3 033218.1_32929120_3 - 0.58 9.8 52.0 0.078 12.6 0.3 8.8 9 0 0 9 9 9 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.6 033218.1_32929120_3 - 0.67 10.2 63.4 0.08 13.1 2.0 12.2 14 0 0 14 14 14 0 Zinc-finger double-stranded RNA-binding V-set PF07686.15 002794.1_26221120_1 - 0.0054 16.7 0.1 0.0086 16.1 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Frag1 PF10277.7 001193971.1_29624001_2 - 2.2e-49 167.8 19.2 2.8e-49 167.5 19.2 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Phage_holin_4_2 PF04020.11 001193971.1_29624001_2 - 0.18 12.4 7.6 0.31 11.6 1.3 2.8 1 1 1 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV zf-CCCH PF00642.22 001194345.1_29622001_2 - 1.1e-07 31.4 1.9 1.1e-07 31.4 1.9 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-U1 PF06220.10 001194345.1_29622001_2 - 3.9e-07 29.6 3.9 7.7e-07 28.6 3.9 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-CCCH_2 PF14608.4 001194345.1_29622001_2 - 0.004 17.5 2.3 0.0089 16.3 2.3 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-C2H2_jaz PF12171.6 001194345.1_29622001_2 - 2.5 8.4 6.8 9.4 6.6 6.8 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding IL34 PF15036.4 001194359.1_29624001_1 - 6.9e-77 256.7 0.5 8.8e-77 256.4 0.5 1.1 1 0 0 1 1 1 1 Interleukin 34 CoA_trans PF01144.21 001319874.1_39724001_2 - 7.8e-121 401.2 0.1 1.2e-73 246.9 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.4 001319874.1_39724001_2 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain CITED PF04487.10 001308562.1_39524001_2 - 3.9e-100 334.0 5.5 5.2e-100 333.6 5.5 1.2 1 0 0 1 1 1 1 CITED Cloacin PF03515.12 001308562.1_39524001_2 - 0.11 12.1 6.3 0.17 11.4 6.3 1.3 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain DUF5102 PF17104.3 001308823.1_49825001_1 - 0.03 14.2 0.3 0.054 13.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) TNFR_c6 PF00020.16 001308823.1_49825001_3 - 2.8e-19 69.1 51.2 1.2e-07 31.9 6.2 4.6 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region Adaptin_N PF01602.18 001266208.2_29629001_2 - 4.8e-148 493.9 4.1 5.7e-148 493.6 4.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.14 001266208.2_29629001_2 - 2.8e-44 149.8 0.0 5.2e-44 148.9 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.18 001266208.2_29629001_2 - 4.8e-20 71.8 0.1 1.1e-19 70.6 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.5 001266208.2_29629001_2 - 2.8e-07 30.5 0.6 1.9e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.4 001266208.2_29629001_2 - 1.9e-05 24.8 2.0 0.0043 17.3 0.2 4.2 3 1 0 3 3 3 1 HEAT repeats RIX1 PF08167.10 001266208.2_29629001_2 - 0.0022 17.7 2.1 0.024 14.3 0.1 3.1 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT PF02985.20 001266208.2_29629001_2 - 0.068 13.3 4.2 70 3.9 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Dymeclin PF09742.7 001266208.2_29629001_2 - 0.1 10.9 0.8 0.15 10.4 0.8 1.2 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein DUF1075 PF06388.9 001194873.2_29623001_3 - 7e-51 171.8 0.0 9.8e-51 171.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Adap_comp_sub PF00928.19 001194895.1_29626001_1 - 2.8e-47 161.2 0.0 3.6e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family BSMAP PF12280.6 001194651.1_29624001_3 - 3.6e-68 229.2 0.5 4.8e-68 228.8 0.5 1.2 1 0 0 1 1 1 1 Brain specific membrane anchored protein Uteroglobin PF01099.15 001193438.1_29621001_3 - 1.5e-15 57.0 0.4 1.9e-15 56.7 0.4 1.2 1 0 0 1 1 1 1 Uteroglobin family DUF2464 PF10240.7 001194120.1_29625001_3 - 1.1 8.6 7.2 1.2 8.4 1.2 2.4 2 1 0 2 2 2 0 Multivesicular body subunit 12 Crystall PF00030.17 001166011.2_29622001_1 - 1.7e-55 185.1 2.8 4.6e-29 100.3 0.1 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin CD20 PF04103.13 001302420.1_39725001_2 - 4.5e-05 23.4 1.7 8.8e-05 22.5 1.7 1.4 1 0 0 1 1 1 1 CD20-like family TIR PF01582.18 001319611.1_29525001_1 - 1.6e-27 96.3 0.3 3.8e-27 95.1 0.3 1.7 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001319611.1_29525001_1 - 1.3e-20 72.7 39.1 1e-10 41.1 3.8 7.9 3 2 5 9 9 9 7 Leucine rich repeat LRR_4 PF12799.5 001319611.1_29525001_1 - 9.2e-19 67.0 43.8 6.7e-06 26.2 0.3 9.0 6 2 3 9 9 9 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001319611.1_29525001_1 - 4e-12 46.2 0.0 1.1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001319611.1_29525001_1 - 6.1e-07 29.0 7.5 0.061 12.7 0.2 3.5 3 0 0 3 3 3 3 Leucine-rich repeat LRRCT PF01463.22 001319611.1_29525001_1 - 5.8e-06 26.3 0.0 2e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_6 PF13516.4 001319611.1_29525001_1 - 0.00057 19.6 28.1 2.5 8.2 0.0 10.3 11 0 0 11 11 11 2 Leucine Rich repeat LRR_1 PF00560.31 001319611.1_29525001_1 - 0.002 18.2 31.0 7.6 7.3 0.0 11.1 9 2 0 9 9 9 2 Leucine Rich Repeat Tautomerase PF01361.19 001319611.1_29525001_1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Tautomerase enzyme Thyroglobulin_1 PF00086.16 001314219.1_09023001_1 - 1.6e-17 62.8 1.8 4.1e-17 61.5 1.8 1.7 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001314219.1_09023001_1 - 1.4e-10 41.5 21.5 1.4e-10 41.5 21.5 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Fibrinogen_C PF00147.16 001308589.1_39524001_3 - 1.8e-52 178.2 0.0 2.5e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain SlyX PF04102.10 001308589.1_39524001_3 - 0.00061 20.2 6.8 0.0057 17.1 6.5 2.4 2 0 0 2 2 2 1 SlyX Spc7 PF08317.9 001308589.1_39524001_3 - 0.0038 16.0 0.7 0.0057 15.4 0.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein MAD PF05557.11 001308589.1_39524001_3 - 0.0041 15.4 0.1 0.0052 15.1 0.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein IncA PF04156.12 001308589.1_39524001_3 - 0.0072 16.0 0.3 0.015 15.0 0.3 1.5 1 0 0 1 1 1 1 IncA protein Exonuc_VII_L PF02601.13 001308589.1_39524001_3 - 0.022 14.2 0.8 0.03 13.7 0.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ADIP PF11559.6 001308589.1_39524001_3 - 0.025 14.5 3.3 0.044 13.7 3.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.13 001308589.1_39524001_3 - 0.027 14.1 4.7 0.051 13.2 4.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Atg14 PF10186.7 001308589.1_39524001_3 - 0.033 13.2 1.7 0.048 12.6 1.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Muted PF14942.4 001308589.1_39524001_3 - 0.08 13.1 1.2 0.13 12.5 1.2 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF16 PF01519.14 001308589.1_39524001_3 - 0.091 13.1 1.3 0.16 12.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 COG5 PF10392.7 001308589.1_39524001_3 - 0.092 12.8 1.6 0.15 12.1 1.6 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Guanylate_cyc_2 PF09778.7 001308589.1_39524001_3 - 0.12 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Guanylylate cyclase ABC_tran_Xtn PF12848.5 001308589.1_39524001_3 - 0.42 10.5 3.8 0.74 9.7 3.8 1.4 1 0 0 1 1 1 0 ABC transporter Fib_alpha PF08702.8 001308589.1_39524001_3 - 0.63 10.1 3.1 2.2 8.3 3.3 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.3 001308589.1_39524001_3 - 1.7 8.6 9.9 3.1 7.8 9.9 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor VKOR PF07884.12 001266931.2_29622001_2 - 4.3e-29 101.1 8.1 4.3e-29 101.1 8.1 1.6 2 0 0 2 2 2 1 Vitamin K epoxide reductase family MOZART2 PF12926.5 001193944.1_29622001_3 - 9.4e-40 134.0 0.0 1.3e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Cu2_monoox_C PF03712.13 001278345.1_29624001_1 - 1.4e-65 219.5 0.1 2e-65 218.9 0.1 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.18 001278345.1_29624001_1 - 6.3e-49 165.4 0.8 1.2e-48 164.5 0.8 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.15 001278345.1_29624001_1 - 6.8e-25 87.6 0.0 1.2e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Clat_adaptor_s PF01217.18 001172150.1_45726001_2 - 3.2e-56 189.1 1.9 5.7e-56 188.3 1.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UPF0258 PF06789.10 001194061.1_29622001_1 - 3.3e-38 131.3 0.0 5.2e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) Patatin PF01734.20 001308576.1_39524001_1 - 2.1e-14 54.0 0.5 4.3e-07 30.2 0.3 2.5 2 0 0 2 2 2 2 Patatin-like phospholipase UQ_con PF00179.24 001302433.1_39725001_1 - 2e-17 63.0 0.0 3e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NAD_binding_4 PF07993.10 001319417.1_29524001_3 - 7.7e-74 248.0 0.0 1.2e-73 247.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.17 001319417.1_29524001_3 - 7.1e-32 109.4 0.6 1.8e-31 108.0 0.6 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.19 001319417.1_29524001_3 - 2.5e-06 27.0 0.0 1.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.17 001319417.1_29524001_3 - 4.6e-06 25.7 0.0 2.6e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.13 001319417.1_29524001_3 - 1.9e-05 23.8 0.2 6.8e-05 22.0 0.1 1.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.22 001319417.1_29524001_3 - 0.0002 21.7 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.15 001319417.1_29524001_3 - 0.00086 18.4 0.5 4.7 6.1 0.0 3.8 3 1 0 3 3 3 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.3 001319417.1_29524001_3 - 0.00089 18.6 0.1 0.0063 15.8 0.1 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.8 001319417.1_29524001_3 - 0.097 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain PP2C PF00481.19 001193781.1_29625001_3 - 5.1e-31 108.1 0.0 3.4e-14 53.0 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.10 001193781.1_29625001_3 - 1.2e-08 35.0 0.2 0.0016 18.2 0.1 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.4 001193781.1_29625001_3 - 0.0081 15.7 0.0 0.029 13.9 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SPT_ssu-like PF11779.6 001193346.1_29626001_3 - 3.5e-19 68.0 7.1 8.4e-19 66.8 7.1 1.7 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RAI16-like PF10257.7 001194481.1_29627001_3 - 2.8e-96 322.4 0.9 4e-96 321.9 0.9 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Lamp PF01299.15 001194698.1_29624001_2 - 9.2e-21 74.6 0.0 9.2e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.10 001194698.1_29624001_2 - 3.3e-05 23.6 0.1 7.6e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Chordopox_A13L PF05961.9 001194698.1_29624001_2 - 0.15 12.2 0.6 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus A13L protein RRM_1 PF00076.20 001194049.1_29624001_2 - 5.2e-18 64.5 0.0 8.3e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hormone_recep PF00104.28 001194697.1_29625001_3 - 1.9e-27 96.1 0.2 3.3e-27 95.3 0.2 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001194697.1_29625001_3 - 1e-24 86.6 15.9 2.3e-24 85.5 15.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Aldedh PF00171.20 001319356.1_29524001_3 - 1.5e-171 570.9 0.0 1.8e-171 570.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.9 001319356.1_29524001_3 - 0.082 12.2 0.0 0.61 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) FAM181 PF15238.4 001194034.1_29624001_3 - 2.6e-28 99.6 0.3 3.9e-21 76.0 0.1 2.3 2 0 0 2 2 2 2 FAM181 CYTL1 PF15153.4 001194003.1_29621001_1 - 1.4e-57 192.9 1.2 1.6e-57 192.7 1.2 1.0 1 0 0 1 1 1 1 Cytokine-like protein 1 Thoc2 PF11732.6 001194003.1_29621001_1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 1 0 1 1 1 0 Transcription- and export-related complex subunit Mito_carr PF00153.25 001194614.1_29623001_1 - 5.1e-65 215.3 1.0 7.5e-21 73.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_8 PF13855.4 001319612.1_29525001_1 - 2.4e-24 84.7 49.6 4.1e-11 42.3 6.6 6.3 3 2 3 6 6 6 6 Leucine rich repeat TIR PF01582.18 001319612.1_29525001_1 - 4.4e-24 85.1 0.3 8.1e-24 84.2 0.3 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001319612.1_29525001_1 - 1.1e-14 54.0 40.2 1.9e-06 27.9 0.4 8.4 4 3 6 10 10 10 9 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001319612.1_29525001_1 - 1.5e-07 31.5 0.0 2.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001319612.1_29525001_1 - 1.9e-06 27.4 39.1 1.4 9.5 0.1 12.0 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.4 001319612.1_29525001_1 - 4.6e-05 23.0 32.9 3.9 7.7 0.0 11.4 11 0 0 11 11 11 3 Leucine Rich repeat LRRCT PF01463.22 001319612.1_29525001_1 - 0.0015 18.8 0.3 0.016 15.5 0.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.4 001319612.1_29525001_1 - 0.0023 17.3 15.7 0.079 12.3 0.2 3.7 2 1 2 4 4 4 2 Leucine-rich repeat Methyltransf_15 PF09445.8 001319612.1_29525001_1 - 0.1 12.3 1.1 0.2 11.3 0.4 1.9 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Lectin_C PF00059.19 001194753.1_29622001_3 - 8.3e-16 58.5 1.5 1.8e-15 57.4 1.5 1.6 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.10 001194753.1_29622001_3 - 0.0083 15.7 0.2 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Trypsin PF00089.24 001194833.1_29622001_1 - 1.1e-63 214.9 0.0 1.2e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001194833.1_29622001_1 - 0.00012 22.9 0.0 0.0004 21.1 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C31 PF05410.11 001194833.1_29622001_1 - 0.047 13.6 0.4 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha PAS_3 PF08447.10 001308560.1_39525001_1 - 2.3e-23 82.1 0.0 1.9e-17 63.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.23 001308560.1_39525001_1 - 2.9e-23 81.9 0.0 9e-14 51.3 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001308560.1_39525001_1 - 1.4e-21 76.5 0.9 7.6e-19 67.8 0.4 3.0 2 1 1 3 3 3 1 PAS domain HLH PF00010.24 001308560.1_39525001_1 - 2.1e-15 56.2 1.1 4.9e-15 55.1 1.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.5 001308560.1_39525001_1 - 4.5e-11 42.8 0.1 3.1e-08 33.7 0.1 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001308560.1_39525001_1 - 0.00024 21.2 0.0 0.12 12.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.9 001308560.1_39525001_1 - 0.012 16.2 0.0 0.17 12.5 0.0 2.3 2 0 0 2 2 2 0 PAS fold eIF-3c_N PF05470.10 001302417.1_39726001_1 - 4.2e-271 900.4 34.3 1.7e-269 895.1 34.3 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.25 001302417.1_39726001_1 - 4.8e-17 62.2 0.1 1.5e-16 60.6 0.1 1.9 1 0 0 1 1 1 1 PCI domain LAM_C PF12544.6 001302417.1_39726001_1 - 2.6 8.1 9.0 0.2 11.7 2.7 2.4 1 1 1 2 2 2 0 Lysine-2,3-aminomutase PBP PF01161.18 001190951.1_29622001_1 - 1.9e-16 60.4 0.0 2.6e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ParBc PF02195.16 001194557.1_29626001_3 - 3.3e-07 30.4 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ParB-like nuclease domain Peptidase_C101 PF16218.3 001193791.2_29624001_1 - 4.9e-119 396.3 0.4 6.4e-119 396.0 0.4 1.1 1 0 0 1 1 1 1 Peptidase family C101 SPT_ssu-like PF11779.6 001193354.1_29621001_1 - 2.7e-16 58.8 5.4 3.7e-16 58.3 5.4 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Fibrinogen_C PF00147.16 001109811.2_29626001_1 - 9.9e-74 247.7 12.0 1.4e-73 247.2 12.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EzrA PF06160.10 001109811.2_29626001_1 - 0.11 10.5 10.2 0.16 10.0 10.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fer4_NifH PF00142.16 001109811.2_29626001_1 - 0.25 10.6 0.4 0.51 9.6 0.4 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 7tm_4 PF13853.4 001309002.1_29722001_1 - 3.2e-52 177.9 22.6 3.7e-52 177.7 22.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001309002.1_29722001_1 - 9.9e-24 83.9 27.5 2.2e-23 82.7 27.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001309002.1_29722001_1 - 2.6e-05 23.6 22.0 4.4e-05 22.8 22.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx HTH_psq PF05225.14 001172360.1_29629001_2 - 1.5e-23 82.1 0.0 1.8e-15 56.3 0.0 2.7 2 0 0 2 2 2 2 helix-turn-helix, Psq domain Defensin_beta_2 PF13841.4 001193390.1_29621001_1 - 7.8e-07 29.3 11.7 1.5e-06 28.4 11.7 1.5 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.17 001193390.1_29621001_1 - 0.0014 18.5 6.2 0.0014 18.5 6.2 1.6 2 0 0 2 2 2 1 Beta defensin DUF2181 PF10223.7 001194307.1_29623001_3 - 2.9e-102 341.1 0.2 3.5e-102 340.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) AIF-MLS PF14962.4 001193816.1_29623001_1 - 9.9e-103 342.0 13.4 9.9e-103 342.0 13.4 2.0 2 0 0 2 2 2 1 Mitochondria Localisation Sequence SIMPL PF04402.12 001194610.1_29623001_1 - 4.6e-22 79.3 0.2 6e-22 79.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Transglut_C PF00927.20 001194610.1_29623001_1 - 0.038 14.0 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain PCNP PF15473.4 135229.1_26226120_3 - 2.8e-46 158.0 2.8 4.2e-46 157.4 2.8 1.2 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family PDZ PF00595.22 135796.1_26229120_2 - 2.5e-16 59.6 0.6 3.9e-16 59.0 0.6 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) I-set PF07679.14 135067.1_26225120_1 - 1.9e-12 46.9 0.0 2.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.4 135067.1_26225120_1 - 5e-12 46.1 0.0 9.5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 135067.1_26225120_1 - 1.7e-05 25.0 0.0 3.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 135067.1_26225120_1 - 6.4e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.15 135067.1_26225120_1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain PARP PF00644.18 130117.1_26228120_1 - 2.7e-41 141.4 0.8 4.5e-41 140.6 0.8 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-CCCH PF00642.22 130117.1_26228120_2 - 0.0001 22.0 3.3 0.0001 22.0 3.3 4.7 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WWE PF02825.18 130117.1_26228120_2 - 0.00013 22.3 8.0 0.026 14.9 0.0 2.4 2 0 0 2 2 2 2 WWE domain Torus PF16131.3 130117.1_26228120_2 - 0.012 16.1 12.9 0.25 11.9 1.8 3.5 3 0 0 3 3 3 0 Torus domain Pkinase PF00069.23 103997.1_26227120_1 - 1.2e-09 37.8 0.0 1.7e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 103997.1_26227120_1 - 0.00012 21.3 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 103997.1_26227120_3 - 0.074 12.3 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein kinase domain DUF4402 PF14352.4 111931.1_26229120_3 - 1.5 9.3 5.9 1.2 9.7 3.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4402) Adap_comp_sub PF00928.19 135191.1_26229120_2 - 1.6e-51 175.1 0.1 2.2e-51 174.6 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.18 135191.1_26229120_2 - 1.5e-05 24.8 0.1 2.7e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.19 135191.1_26229120_3 - 3.6e-16 59.2 0.0 5.3e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family V-set PF07686.15 027293.2_26225120_1 - 1.1e-17 64.0 0.7 1.9e-17 63.3 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain RIBIOP_C PF04950.10 027293.2_26225120_1 - 1.1e-14 54.4 2.3 3.9e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Ig_3 PF13927.4 027293.2_26225120_1 - 0.00033 21.1 0.2 0.00068 20.1 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 027293.2_26225120_1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.15 027293.2_26225120_2 - 8e-20 70.9 0.1 1.7e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.4 027293.2_26225120_2 - 4.8e-06 27.0 0.0 1.6e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 027293.2_26225120_2 - 0.079 13.0 0.2 0.4 10.8 0.1 2.3 2 1 0 2 2 2 0 Immunoglobulin domain I-set PF07679.14 027293.2_26225120_2 - 0.15 12.1 0.0 0.46 10.4 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain RIBIOP_C PF04950.10 027293.2_26225120_3 - 8.8e-35 120.4 0.1 1.2e-34 120.0 0.1 1.1 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal cEGF PF12662.5 021485.2_26228120_1 - 8.9e-07 28.6 24.9 0.00012 21.8 2.2 3.0 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_CA PF07645.13 021485.2_26228120_1 - 1.7e-05 24.8 14.9 1.7e-05 24.8 14.9 3.7 3 0 0 3 3 3 1 Calcium-binding EGF domain FXa_inhibition PF14670.4 021485.2_26228120_1 - 0.014 15.5 38.3 0.016 15.3 8.1 3.1 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site EGF PF00008.25 021485.2_26228120_1 - 1.8 8.8 22.2 1.1 9.5 10.1 3.1 2 0 0 2 2 2 0 EGF-like domain FXa_inhibition PF14670.4 021485.2_26228120_2 - 0.0021 18.2 0.1 0.0021 18.2 0.1 6.8 6 1 0 6 6 6 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.13 021485.2_26228120_2 - 0.0025 17.9 1.0 0.0025 17.9 1.0 5.7 5 0 0 5 5 5 1 Calcium-binding EGF domain EGF_2 PF07974.11 021485.2_26228120_2 - 2.2 8.6 80.9 0.017 15.3 8.7 6.4 5 1 1 6 6 6 0 EGF-like domain FXa_inhibition PF14670.4 021485.2_26228120_3 - 2.3e-17 62.8 71.3 3.2e-06 27.2 15.3 5.1 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site EGF_CA PF07645.13 021485.2_26228120_3 - 2.4e-14 53.1 59.8 7.1e-07 29.2 10.5 4.7 4 0 0 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.5 021485.2_26228120_3 - 7.2e-14 51.3 24.7 2.2e-06 27.4 0.4 5.0 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.25 021485.2_26228120_3 - 0.88 9.8 51.7 0.032 14.4 2.2 4.8 4 0 0 4 4 4 0 EGF-like domain Collagen PF01391.16 027898.1_26229120_1 - 5.8e-35 118.7 134.1 6.4e-09 35.3 25.5 5.7 1 1 4 5 5 5 5 Collagen triple helix repeat (20 copies) Kunitz_BPTI PF00014.21 027898.1_26229120_1 - 5.5e-15 55.2 10.9 1.6e-14 53.7 10.9 1.9 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain VWA PF00092.26 027898.1_26229120_1 - 5.6e-10 39.6 0.0 8.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.26 027898.1_26229120_2 - 0.046 13.9 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA PF00092.26 027898.1_26229120_3 - 0.077 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Heme_oxygenase PF01126.18 045198.1_45725120_2 - 1.1e-13 51.3 0.1 1.7e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Heme oxygenase Heme_oxygenase PF01126.18 045198.1_45725120_3 - 1.6e-14 54.1 4.2 1.4e-06 28.1 1.1 2.1 2 0 0 2 2 2 2 Heme oxygenase TLV_coat PF00429.17 130958.1_32929120_1 - 2e-47 162.0 15.5 4.6e-43 147.6 0.4 2.1 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) TLV_coat PF00429.17 130958.1_32929120_3 - 2.8e-48 164.8 0.8 3.8e-48 164.4 0.8 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) LRR_8 PF13855.4 001329083.1_37927001_2 - 1.2e-57 191.3 63.1 6.7e-12 44.9 1.9 9.6 7 2 3 10 10 10 9 Leucine rich repeat TIR PF01582.18 001329083.1_37927001_2 - 1.4e-32 112.8 2.7 2.2e-32 112.1 2.7 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001329083.1_37927001_2 - 4e-28 96.8 49.5 1.5e-05 25.1 0.5 11.2 9 1 2 11 11 11 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001329083.1_37927001_2 - 2e-12 47.0 0.3 3.8e-06 26.7 0.1 4.1 3 2 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001329083.1_37927001_2 - 9.8e-08 31.6 17.4 0.022 14.1 0.9 4.9 3 2 2 5 5 5 5 Leucine-rich repeat TIR_2 PF13676.4 001329083.1_37927001_2 - 1.5e-05 25.1 0.1 3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001329083.1_37927001_2 - 0.0001 22.1 46.4 5.5 7.7 0.0 14.6 11 2 1 12 12 12 1 Leucine Rich Repeat LRR_6 PF13516.4 001329083.1_37927001_2 - 0.0056 16.5 37.4 21 5.4 1.1 12.9 14 0 0 14 14 14 0 Leucine Rich repeat FNIP PF05725.10 001329083.1_37927001_2 - 0.0064 16.5 0.0 3.4 7.8 0.0 4.4 2 2 0 2 2 2 1 FNIP Repeat LRRCT PF01463.22 001329083.1_37927001_2 - 0.016 15.6 0.4 20 5.9 0.0 4.1 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain Clat_adaptor_s PF01217.18 001242425.1_39729001_1 - 1.5e-50 170.7 2.9 2.1e-50 170.2 2.9 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Kazal_1 PF00050.19 001329077.1_37926001_1 - 3.3e-11 42.9 20.4 0.00048 20.0 1.7 5.1 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 001329077.1_37926001_1 - 4.9e-11 42.5 30.9 4.5e-05 23.4 0.4 5.6 5 0 0 5 5 5 3 Kazal-type serine protease inhibitor domain Pacifastin_I PF05375.11 001329077.1_37926001_1 - 3e-07 29.9 1.0 3e-07 29.9 1.0 4.4 3 0 0 3 3 3 1 Pacifastin inhibitor (LCMII) DNA_pol_E_B PF04042.14 001329077.1_37926001_1 - 0.038 13.2 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B EF-hand_1 PF00036.30 001243106.1_39722001_1 - 5.6e-27 91.1 14.0 8.6e-07 28.0 0.3 4.8 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.4 001243106.1_39722001_1 - 2.4e-23 80.4 9.2 1.1e-06 27.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.4 001243106.1_39722001_1 - 3.7e-23 81.6 4.1 2.2e-12 47.1 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001243106.1_39722001_1 - 3.2e-22 76.4 7.7 3.3e-05 23.3 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.4 001243106.1_39722001_1 - 6.6e-17 60.9 11.2 0.002 17.7 0.1 4.3 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001243106.1_39722001_1 - 7.5e-08 32.6 0.1 0.0067 16.6 0.0 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001243106.1_39722001_1 - 1.4e-05 24.8 6.6 0.12 12.2 0.6 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001243106.1_39722001_1 - 0.00012 22.3 0.1 0.011 15.9 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain YtfJ_HI0045 PF09695.8 001243106.1_39722001_1 - 0.0021 17.6 0.8 0.13 11.8 0.8 2.2 1 1 0 1 1 1 1 Bacterial protein of unknown function (YtfJ_HI0045) Toprim_2 PF13155.4 001243106.1_39722001_1 - 0.055 13.8 0.1 3 8.3 0.0 2.9 1 1 3 4 4 4 0 Toprim-like PIG-Y PF15159.4 001270955.1_39723001_3 - 1.6e-17 63.9 3.0 2.6e-17 63.2 3.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Trm112p PF03966.14 001270955.1_39723001_3 - 1.8e-07 31.5 0.0 4.2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Trm112p-like protein Actin PF00022.17 001328277.1_39725001_3 - 3.7e-85 285.9 0.0 7.3e-52 176.2 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.11 001328277.1_39725001_3 - 0.00061 18.6 0.0 0.43 9.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Robl_LC7 PF03259.15 001328277.1_39725001_3 - 0.16 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain TIR PF01582.18 001329082.1_37925001_1 - 2.2e-27 95.8 0.4 3.6e-27 95.1 0.4 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001329082.1_37925001_1 - 1.9e-18 65.8 31.9 2.1e-08 33.6 1.6 6.9 4 2 3 7 7 7 5 Leucine rich repeat LRR_4 PF12799.5 001329082.1_37925001_1 - 7e-15 54.7 44.2 0.00014 22.0 0.2 8.8 6 3 4 10 10 10 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001329082.1_37925001_1 - 1.7e-13 50.6 0.0 3.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001329082.1_37925001_1 - 0.00065 19.4 22.5 7.5 6.8 0.0 8.9 8 0 0 8 8 8 1 Leucine Rich repeat APA3_viroporin PF11289.6 001329082.1_37925001_1 - 0.0047 16.4 0.2 0.0099 15.3 0.2 1.5 1 0 0 1 1 1 1 Coronavirus accessory protein 3a LRR_9 PF14580.4 001329082.1_37925001_1 - 0.028 13.8 9.7 0.89 8.9 0.1 3.6 3 1 1 4 4 4 0 Leucine-rich repeat Pkinase PF00069.23 001328324.1_39725001_2 - 5.1e-64 216.0 0.1 7.5e-64 215.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001328324.1_39725001_2 - 1.3e-35 122.8 0.0 1.8e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001328324.1_39725001_2 - 2.1e-09 37.0 0.0 3.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.12 001328324.1_39725001_2 - 0.0025 17.0 0.2 0.004 16.4 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.7 001328324.1_39725001_2 - 0.045 13.1 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TIR_2 PF13676.4 001195204.3_39727001_1 - 3.2e-07 30.5 0.0 4.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001195204.3_39727001_1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 TIR domain Crystall PF00030.17 001122894.2_29622001_2 - 3.8e-59 196.7 0.3 5.1e-30 103.4 0.0 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001122894.2_29622001_2 - 3.2e-06 26.8 0.1 0.028 14.2 0.0 2.9 3 0 0 3 3 3 2 Peptidase inhibitor family I36 Crystall_3 PF08964.8 001122894.2_29622001_2 - 1.3e-05 25.1 0.5 0.17 11.9 0.0 3.8 3 1 1 4 4 4 2 Beta/Gamma crystallin SOSSC PF15925.3 138056.1_26228120_3 - 7.3e-13 49.6 0.0 1.2e-12 48.9 0.0 1.3 1 0 0 1 1 1 1 SOSS complex subunit C CCDC144C PF14915.4 138091.1_26227120_1 - 1e-78 264.5 48.8 8.9e-50 169.4 29.0 3.5 4 0 0 4 4 4 2 CCDC144C protein coiled-coil region Ank PF00023.28 138091.1_26227120_1 - 1.1e-05 25.5 0.0 0.25 11.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.5 138091.1_26227120_1 - 1.6e-05 25.3 0.1 3.3e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.4 138091.1_26227120_1 - 5.3e-05 23.2 0.1 0.2 12.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.4 138091.1_26227120_1 - 0.0044 17.2 0.0 0.35 11.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3496 PF12001.6 138091.1_26227120_3 - 1.6e-36 124.8 6.7 1.6e-36 124.8 6.7 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3496) IFNGR1 PF07140.9 001131272.1_43525001_3 - 1.7e-45 154.3 7.2 3.3e-45 153.3 7.2 1.4 1 0 0 1 1 1 1 Interferon gamma receptor (IFNGR1) Tissue_fac PF01108.15 001131272.1_43525001_3 - 3.6e-19 68.4 0.0 7.8e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.8 001131272.1_43525001_3 - 1.4e-08 34.9 0.6 3.2e-08 33.7 0.6 1.6 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III RanGAP1_C PF07834.9 001134177.1_43527001_1 - 1.5e-74 249.3 0.4 3.1e-74 248.4 0.4 1.5 1 0 0 1 1 1 1 RanGAP1 C-terminal domain LRR_6 PF13516.4 001134177.1_43527001_1 - 8.1e-15 53.4 5.1 0.19 11.7 0.0 8.8 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.5 001134177.1_43527001_1 - 3.2e-05 24.0 3.9 2.6 8.5 0.0 5.0 4 1 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001134177.1_43527001_1 - 9.9e-05 21.9 0.1 1 9.0 0.0 4.6 4 1 0 4 4 4 1 Leucine rich repeat SDA1 PF05285.10 001134177.1_43527001_1 - 0.001 18.5 14.6 0.0018 17.6 14.6 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.10 001134177.1_43527001_1 - 0.03 12.4 19.5 0.046 11.8 19.5 1.2 1 0 0 1 1 1 0 Nop14-like family CPSF100_C PF13299.4 001134177.1_43527001_1 - 0.037 14.1 7.9 0.065 13.3 7.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal IFN-gamma PF00714.15 001134177.1_43527001_1 - 0.043 13.5 0.2 0.08 12.7 0.2 1.4 1 0 0 1 1 1 0 Interferon gamma LRR_1 PF00560.31 001134177.1_43527001_1 - 0.044 14.1 3.1 52 4.8 0.0 5.3 6 0 0 6 6 4 0 Leucine Rich Repeat SpoIIP PF07454.9 001134177.1_43527001_1 - 0.093 12.0 5.3 0.16 11.2 5.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DNA_pol_phi PF04931.11 001134177.1_43527001_1 - 0.17 9.8 27.5 0.29 9.1 27.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4471 PF14740.4 001134177.1_43527001_1 - 0.19 10.7 0.3 0.28 10.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) CDC45 PF02724.12 001134177.1_43527001_1 - 0.22 9.7 14.5 0.32 9.1 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.10 001134177.1_43527001_1 - 0.4 9.9 25.6 0.76 9.0 25.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Plasmodium_Vir PF05795.9 001134177.1_43527001_1 - 0.42 9.8 4.8 0.61 9.3 4.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mpp10 PF04006.10 001134177.1_43527001_1 - 0.53 8.5 22.3 0.76 8.0 22.3 1.1 1 0 0 1 1 1 0 Mpp10 protein RNA_pol_Rpc4 PF05132.12 001134177.1_43527001_1 - 0.55 10.6 5.6 0.91 9.8 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 BUD22 PF09073.8 001134177.1_43527001_1 - 1.4 8.0 19.3 0.32 10.2 16.1 1.4 2 0 0 2 2 2 0 BUD22 Tim54 PF11711.6 001134177.1_43527001_1 - 1.5 7.4 8.5 2.2 6.8 8.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.7 001134177.1_43527001_1 - 1.8 8.5 20.9 3.1 7.8 20.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Paf1 PF03985.11 001134177.1_43527001_1 - 3.5 6.4 26.7 4.7 6.0 26.7 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.10 001134177.1_43527001_1 - 3.9 7.1 15.4 6.3 6.4 15.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.9 001134177.1_43527001_1 - 4.4 7.1 39.0 7.8 6.3 39.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF1510 PF07423.9 001134177.1_43527001_1 - 6.1 6.1 22.7 9.8 5.4 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC27 PF09507.8 001134177.1_43527001_1 - 6.2 6.0 15.0 9.3 5.4 15.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Drc1-Sld2 PF11719.6 001134177.1_43527001_1 - 7.1 5.9 12.2 11 5.2 12.2 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Na_trans_assoc PF06512.11 001134177.1_43527001_1 - 8.2 6.6 13.8 14 5.8 13.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Presenilin PF01080.15 001134177.1_43527001_1 - 8.2 4.9 7.2 12 4.4 7.2 1.1 1 0 0 1 1 1 0 Presenilin FYTT PF07078.9 001133462.1_43527001_3 - 2.4e-166 552.5 18.0 2.9e-166 552.3 18.0 1.1 1 0 0 1 1 1 1 Forty-two-three protein SCAN PF02023.15 001133884.1_43524001_2 - 3.1e-39 132.5 0.8 1.2e-38 130.7 0.9 2.0 2 0 0 2 2 2 1 SCAN domain DDE_Tnp_1_7 PF13843.4 001133884.1_43524001_2 - 5.2e-37 127.8 1.0 7.9e-37 127.2 1.0 1.2 1 0 0 1 1 1 1 Transposase IS4 BTG PF07742.10 001131404.1_43529001_2 - 1.3e-35 121.7 0.0 2e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 BTG family PAM2 PF07145.13 001131404.1_43529001_2 - 1.5e-11 43.0 0.2 8.3e-05 21.9 0.1 3.1 2 0 0 2 2 2 2 Ataxin-2 C-terminal region HSP70 PF00012.18 001133010.1_43529001_2 - 8.7e-103 344.4 5.6 4.6e-102 342.0 5.6 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001133010.1_43529001_2 - 2.2e-06 26.6 0.6 8.6e-05 21.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein AbiEi_3_N PF17194.2 001133010.1_43529001_2 - 0.012 15.5 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain BBS1 PF14779.4 001133807.2_43527001_1 - 2.3e-95 318.7 0.0 5.4e-95 317.5 0.0 1.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.4 001133807.2_43527001_1 - 1.5e-05 24.9 0.0 0.0034 17.3 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region RRM_1 PF00076.20 001132105.1_43528001_2 - 2.3e-10 40.0 0.1 0.0009 18.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001132105.1_43528001_2 - 4.8e-07 29.5 0.0 0.00029 20.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.15 001132105.1_43528001_2 - 0.00025 21.1 0.2 0.00053 20.1 0.2 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.22 001132105.1_43528001_2 - 0.00097 18.9 2.7 0.0019 17.9 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FGGY_N PF00370.19 001134002.1_43527001_1 - 7.1e-96 320.4 0.0 9.3e-96 320.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.14 001134002.1_43527001_1 - 4.7e-64 215.6 0.1 8.1e-64 214.9 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain hSac2 PF12456.6 001131525.1_43527001_1 - 3.6e-15 55.5 0.0 6.7e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase LRR_8 PF13855.4 001199359.1_43529001_1 - 9.9e-07 28.3 1.9 9.9e-07 28.3 1.9 1.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.4 001199359.1_43529001_1 - 0.0014 18.0 0.1 0.003 16.9 0.0 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.5 001199359.1_43529001_1 - 0.0063 16.8 9.9 0.049 13.9 0.4 3.2 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) Methyltransf_3 PF01596.15 001199359.1_43529001_2 - 5.9e-13 48.4 0.0 8.4e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001199359.1_43529001_2 - 3.8e-08 34.2 0.0 6.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 001199359.1_43529001_2 - 0.059 13.0 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GETHR PF05671.9 001132036.1_43526001_1 - 0.28 10.5 2.3 32 3.9 0.1 4.7 4 0 0 4 4 4 0 GETHR pentapeptide repeat (5 copies) zf-C2H2 PF00096.24 001132036.1_43526001_2 - 7.1e-79 256.0 105.6 3.8e-07 30.1 0.4 16.1 16 0 0 16 16 15 15 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001132036.1_43526001_2 - 2.5e-76 248.8 81.2 3.2e-06 27.2 0.4 16.1 15 1 1 16 16 16 14 Zinc-finger double domain zf-C2H2_4 PF13894.4 001132036.1_43526001_2 - 7.9e-46 150.6 106.1 0.004 17.7 0.3 16.9 17 0 0 17 17 17 15 C2H2-type zinc finger KRAB PF01352.25 001132036.1_43526001_2 - 9.6e-25 85.9 0.1 1.7e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 001132036.1_43526001_2 - 5.5e-12 45.5 34.7 4.1 7.7 0.0 13.7 14 0 0 14 14 14 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001132036.1_43526001_2 - 5.4e-09 35.9 58.2 0.062 13.3 0.8 10.1 1 1 12 14 14 14 10 Zinc ribbon domain zf-C2H2_6 PF13912.4 001132036.1_43526001_2 - 1.7e-08 34.1 87.8 0.023 14.5 1.6 15.1 14 1 0 14 14 14 6 C2H2-type zinc finger zinc_ribbon_15 PF17032.3 001132036.1_43526001_2 - 1.5e-07 31.9 45.7 0.43 11.2 0.4 8.0 1 1 9 11 11 11 7 zinc-ribbon family ADK_lid PF05191.12 001132036.1_43526001_2 - 1.8e-06 27.8 48.6 0.033 14.1 0.5 10.4 6 3 3 10 10 10 5 Adenylate kinase, active site lid zf-C2H2_11 PF16622.3 001132036.1_43526001_2 - 0.0002 20.9 84.0 0.21 11.2 0.8 15.0 15 0 0 15 15 15 6 zinc-finger C2H2-type DUF3268 PF11672.6 001132036.1_43526001_2 - 0.0025 18.0 43.8 0.38 11.0 1.2 8.2 4 2 2 8 8 8 4 zinc-finger-containing domain Chordopox_RPO7 PF05864.10 001132036.1_43526001_2 - 0.022 14.9 28.5 24 5.1 0.7 10.4 10 1 1 11 11 11 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-trcl PF13451.4 001132036.1_43526001_2 - 0.04 13.7 53.0 4.2 7.2 0.1 13.4 14 1 0 14 14 14 0 Probable zinc-ribbon domain BHD_1 PF10403.7 001132036.1_43526001_2 - 0.065 12.9 0.2 1.5 8.5 0.0 3.3 4 2 1 5 5 5 0 Rad4 beta-hairpin domain 1 DUF2799 PF10973.6 001132036.1_43526001_3 - 2.6 8.4 5.8 1.5 9.2 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2799) SRF-TF PF00319.16 001205196.1_43523001_1 - 4.1e-23 80.5 0.3 5.8e-23 80.0 0.3 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) BST2 PF16716.3 001172587.1_43522001_1 - 5.1e-36 123.0 8.7 7e-36 122.5 8.7 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 MAD PF05557.11 001172587.1_43522001_1 - 1.5e-05 23.4 6.4 1.8e-05 23.2 6.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein ATG16 PF08614.9 001172587.1_43522001_1 - 0.00027 21.1 7.0 0.00041 20.5 7.0 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.9 001172587.1_43522001_1 - 0.001 17.6 4.1 0.0012 17.4 4.1 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like FlaC_arch PF05377.9 001172587.1_43522001_1 - 0.0076 16.5 2.3 1.8 8.9 0.6 2.6 1 1 0 2 2 2 1 Flagella accessory protein C (FlaC) Tropomyosin PF00261.18 001172587.1_43522001_1 - 0.01 15.1 1.4 0.01 15.1 1.4 1.8 1 1 0 1 1 1 0 Tropomyosin PRKG1_interact PF15898.3 001172587.1_43522001_1 - 0.011 16.5 5.0 0.016 16.0 5.0 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.6 001172587.1_43522001_1 - 0.012 14.8 3.5 0.012 14.8 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.10 001172587.1_43522001_1 - 0.012 15.6 4.3 0.012 15.6 4.3 1.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC-167 PF15188.4 001172587.1_43522001_1 - 0.013 15.7 2.7 0.017 15.3 1.9 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 CENP-F_leu_zip PF10473.7 001172587.1_43522001_1 - 0.018 15.0 2.7 0.018 15.0 2.7 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.7 001172587.1_43522001_1 - 0.026 13.9 5.0 0.031 13.6 5.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4200 PF13863.4 001172587.1_43522001_1 - 0.031 14.5 3.7 0.044 14.0 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Jnk-SapK_ap_N PF09744.7 001172587.1_43522001_1 - 0.032 14.3 4.8 0.043 13.9 4.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4618 PF15397.4 001172587.1_43522001_1 - 0.034 13.5 3.9 0.043 13.1 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Reo_sigmaC PF04582.10 001172587.1_43522001_1 - 0.035 13.4 1.5 0.043 13.1 1.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Filament PF00038.19 001172587.1_43522001_1 - 0.036 13.5 7.0 0.052 13.0 6.1 1.5 1 1 1 2 2 2 0 Intermediate filament protein TMF_TATA_bd PF12325.6 001172587.1_43522001_1 - 0.038 14.1 5.1 0.069 13.2 5.1 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.11 001172587.1_43522001_1 - 0.042 12.3 0.8 0.049 12.1 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fez1 PF06818.13 001172587.1_43522001_1 - 0.046 14.0 3.9 0.062 13.6 3.9 1.2 1 0 0 1 1 1 0 Fez1 Tropomyosin_1 PF12718.5 001172587.1_43522001_1 - 0.068 13.2 7.2 0.088 12.8 2.8 2.0 1 1 1 2 2 2 0 Tropomyosin like FliJ PF02050.14 001172587.1_43522001_1 - 0.07 13.2 4.4 0.17 12.0 4.4 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein APG6 PF04111.10 001172587.1_43522001_1 - 0.079 12.2 4.8 0.1 11.8 4.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HrpB7 PF09486.8 001172587.1_43522001_1 - 0.081 13.2 6.4 0.14 12.4 0.8 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.7 001172587.1_43522001_1 - 0.084 11.8 4.0 0.12 11.3 4.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bap31 PF05529.10 001172587.1_43522001_1 - 0.089 12.3 3.5 0.15 11.5 3.5 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.12 001172587.1_43522001_1 - 0.096 12.3 15.0 0.13 11.9 13.8 1.8 1 1 0 1 1 1 0 IncA protein Spc7 PF08317.9 001172587.1_43522001_1 - 0.1 11.3 6.7 0.14 10.9 6.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Lebercilin PF15619.4 001172587.1_43522001_1 - 0.11 11.9 7.2 0.1 12.1 3.1 1.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.10 001172587.1_43522001_1 - 0.14 12.0 3.5 0.66 9.8 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.4 001172587.1_43522001_1 - 0.15 11.3 6.3 0.089 12.0 2.1 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.9 001172587.1_43522001_1 - 0.18 12.0 7.2 0.16 12.1 2.5 2.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF4472 PF14739.4 001172587.1_43522001_1 - 0.18 12.4 5.9 1.3 9.6 1.3 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Cluap1 PF10234.7 001172587.1_43522001_1 - 0.19 10.9 5.8 0.7 9.1 5.3 1.8 1 1 0 1 1 1 0 Clusterin-associated protein-1 SlyX PF04102.10 001172587.1_43522001_1 - 0.21 12.1 7.6 0.81 10.2 0.8 2.4 1 1 2 3 3 3 0 SlyX GrpE PF01025.17 001172587.1_43522001_1 - 0.22 11.0 4.6 0.13 11.8 2.0 1.7 1 1 0 2 2 2 0 GrpE CHCH PF06747.11 001172587.1_43522001_1 - 0.23 11.5 1.1 2.9 8.0 0.1 2.3 2 0 0 2 2 2 0 CHCH domain CENP-H PF05837.10 001172587.1_43522001_1 - 0.25 11.6 8.9 1.4 9.2 2.0 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF972 PF06156.11 001172587.1_43522001_1 - 0.3 11.6 3.3 1.4 9.5 3.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.20 001172587.1_43522001_1 - 0.35 11.0 4.5 0.46 10.6 4.1 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.13 001172587.1_43522001_1 - 0.39 10.4 5.2 0.52 10.0 5.2 1.1 1 0 0 1 1 1 0 Mnd1 family KELK PF15796.3 001172587.1_43522001_1 - 0.74 10.2 6.4 0.82 10.1 2.3 2.1 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2205 PF10224.7 001172587.1_43522001_1 - 1.6 8.6 5.5 1.3 9.0 2.1 2.0 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DivIC PF04977.13 001172587.1_43522001_1 - 4.1 7.1 8.4 16 5.2 3.9 3.0 1 1 1 2 2 2 0 Septum formation initiator Sec3_C PF09763.7 001133207.1_43527001_1 - 1.4e-182 608.6 21.3 1.8e-182 608.3 21.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.4 001133207.1_43527001_1 - 1.8e-26 92.0 1.9 4.8e-26 90.6 1.9 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF310 PF03750.11 001133207.1_43527001_1 - 0.055 14.2 3.4 0.1 13.3 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF310) FlaC_arch PF05377.9 001133207.1_43527001_1 - 0.19 12.0 5.2 0.51 10.6 2.3 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AKNA PF12443.6 001133207.1_43527001_1 - 0.69 10.4 3.8 1.1 9.9 1.0 2.8 3 1 1 4 4 4 0 AT-hook-containing transcription factor DUF972 PF06156.11 001133207.1_43527001_1 - 2.9 8.5 7.3 1.5 9.3 1.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) SCAMP PF04144.11 001134112.1_43528001_1 - 2.9e-72 242.5 18.5 5.8e-72 241.5 18.5 1.5 1 0 0 1 1 1 1 SCAMP family DED PF01335.19 001132575.1_43524001_2 - 9.6e-15 54.5 0.0 2.2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Death effector domain EF-hand_6 PF13405.4 001131911.1_43529001_1 - 5.7e-06 25.7 0.0 0.065 13.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.4 001131911.1_43529001_1 - 1.2e-05 25.5 0.0 0.094 13.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.4 001131911.1_43529001_1 - 0.0079 16.4 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.30 001131911.1_43529001_1 - 0.012 15.0 0.1 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 EF hand IPK PF03770.14 001131915.1_43526001_1 - 2.2e-63 213.6 0.0 2.2e-63 213.6 0.0 2.1 2 0 0 2 2 2 1 Inositol polyphosphate kinase KAAG1 PF15354.4 001131915.1_43526001_1 - 0.12 12.8 1.3 0.24 11.8 0.3 2.0 2 0 0 2 2 2 0 Kidney-associated antigen 1 AP3D1 PF06375.9 001131915.1_43526001_2 - 0.24 11.6 23.5 0.43 10.7 23.5 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.8 001131915.1_43526001_2 - 3.1 7.7 18.2 4.9 7.1 18.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MCC-bdg_PDZ PF10506.7 001131104.1_43529001_2 - 2.3e-42 142.7 21.2 7.3e-28 96.2 7.4 6.4 6 1 1 7 7 7 2 PDZ domain of MCC-2 bdg protein for Usher syndrome Mod_r PF07200.11 001131104.1_43529001_2 - 0.00038 20.5 0.2 0.00038 20.5 0.2 6.0 5 1 0 5 5 5 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.9 001131104.1_43529001_2 - 0.0028 16.5 3.4 0.0028 16.5 3.4 5.5 4 1 1 5 5 5 2 Spc7 kinetochore protein ERM PF00769.17 001131104.1_43529001_2 - 0.098 12.3 77.3 0.11 12.2 14.6 4.4 4 0 0 4 4 4 0 Ezrin/radixin/moesin family GAS PF13851.4 001131104.1_43529001_2 - 1.9 7.7 67.9 0.28 10.4 1.4 6.4 5 1 1 6 6 6 0 Growth-arrest specific micro-tubule binding APG6 PF04111.10 001131104.1_43529001_2 - 3.4 6.9 72.7 0.08 12.2 1.6 5.4 5 0 0 5 5 5 0 Autophagy protein Apg6 T2SSF PF00482.21 001131104.1_43529001_2 - 7.5 6.4 6.7 1.9 8.3 1.1 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Methyltransf_11 PF08241.10 001133236.1_43527001_2 - 3.1e-20 72.5 0.0 4.8e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 001133236.1_43527001_2 - 1.4e-15 57.5 0.0 2.1e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001133236.1_43527001_2 - 1.1e-13 51.6 0.0 1.8e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001133236.1_43527001_2 - 4.9e-12 46.3 0.0 7.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001133236.1_43527001_2 - 8e-12 45.1 0.0 1.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.16 001133236.1_43527001_2 - 4.4e-07 29.4 0.0 6.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.13 001133236.1_43527001_2 - 4.1e-05 23.4 0.0 6.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase CheR PF01739.16 001133236.1_43527001_2 - 0.07 12.5 0.1 0.52 9.6 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain SCAMP PF04144.11 001132639.1_43525001_2 - 8.8e-70 234.4 15.5 1.4e-69 233.7 15.5 1.3 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.6 001132639.1_43525001_2 - 0.076 12.3 2.1 0.12 11.6 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) KfrA_N PF11740.6 001132639.1_43525001_2 - 0.18 12.4 3.8 0.36 11.4 3.8 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term START PF01852.17 001133732.1_43529001_2 - 1.2e-38 132.5 0.1 1.8e-38 131.9 0.1 1.2 1 0 0 1 1 1 1 START domain 4HBT PF03061.20 001133732.1_43529001_2 - 2.1e-21 75.9 0.3 4.3e-11 42.9 0.0 2.7 2 0 0 2 2 2 2 Thioesterase superfamily Polyketide_cyc2 PF10604.7 001133732.1_43529001_2 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport RRM_1 PF00076.20 001133285.1_43524001_3 - 4e-34 116.1 0.1 1.9e-16 59.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001133285.1_43524001_3 - 1.6e-08 34.0 0.2 0.00014 21.3 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001133285.1_43524001_3 - 8.4e-06 25.7 0.0 0.013 15.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.3 001133285.1_43524001_3 - 0.00011 21.8 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif Calcipressin PF04847.10 001133285.1_43524001_3 - 0.0046 16.6 0.1 3.2 7.3 0.0 2.3 1 1 1 2 2 2 2 Calcipressin DbpA PF03880.13 001133285.1_43524001_3 - 0.011 15.6 0.1 6.4 6.7 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain RNA_bind PF08675.9 001133285.1_43524001_3 - 0.033 14.1 0.0 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain zf-CCHC PF00098.21 001133285.1_43524001_3 - 1.4 9.0 14.8 0.27 11.2 4.2 3.0 3 0 0 3 3 3 0 Zinc knuckle CompInhib_SCIN PF11546.6 001133285.1_43524001_3 - 4.9 7.3 5.9 8.6 6.5 2.9 2.3 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN Ank_5 PF13857.4 001133895.1_43523001_1 - 1e-19 70.2 2.4 2.4e-07 30.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.5 001133895.1_43523001_1 - 1.8e-16 60.3 0.2 7e-16 58.5 0.2 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001133895.1_43523001_1 - 8.5e-15 54.8 0.2 4.3e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) SH3_2 PF07653.15 001133895.1_43523001_1 - 2.4e-12 46.2 0.0 4.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank PF00023.28 001133895.1_43523001_1 - 2.8e-12 46.3 0.1 3.7e-05 23.8 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat SH3_1 PF00018.26 001133895.1_43523001_1 - 3e-12 45.8 0.1 5.6e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 001133895.1_43523001_1 - 1.2e-11 44.1 0.0 2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.4 001133895.1_43523001_1 - 4.3e-09 35.7 0.1 0.0093 16.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat EOS1 PF12326.6 001133895.1_43523001_1 - 0.16 11.7 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein EOS1 PF12326.6 001133895.1_43523001_3 - 0.15 11.8 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein zf-H2C2_2 PF13465.4 001133055.1_43529001_3 - 4.7e-49 162.6 84.5 3.7e-08 33.3 0.3 12.6 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2 PF00096.24 001133055.1_43529001_3 - 9.7e-27 91.8 91.2 0.0002 21.5 1.4 12.7 13 0 0 13 13 13 10 Zinc finger, C2H2 type KRAB PF01352.25 001133055.1_43529001_3 - 7.9e-22 76.5 0.2 1.8e-21 75.4 0.2 1.6 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001133055.1_43529001_3 - 9e-13 47.8 89.7 0.045 14.4 0.8 13.2 12 0 0 12 12 12 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001133055.1_43529001_3 - 0.26 11.3 55.2 0.052 13.5 2.6 7.7 4 3 4 8 8 8 0 Zinc ribbon domain COX7a PF02238.13 001131554.1_43524001_3 - 4.4e-09 36.5 0.1 1.3e-08 35.0 0.1 1.9 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Met_synt_B12 PF02965.15 001132713.1_43529001_1 - 1e-112 375.9 0.0 1.5e-112 375.4 0.0 1.2 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding_2 PF02607.15 001132713.1_43529001_1 - 1e-24 86.6 0.0 2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Pterin_bind PF00809.20 001132713.1_43529001_1 - 1.9e-21 76.8 0.0 3.4e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding PF02310.17 001132713.1_43529001_1 - 4.8e-18 65.2 0.2 8.5e-18 64.4 0.2 1.3 1 0 0 1 1 1 1 B12 binding domain DUF2760 PF10816.6 001132713.1_43529001_1 - 0.18 11.5 0.1 17 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) Pterin_bind PF00809.20 001132713.1_43529001_3 - 3e-12 46.6 0.0 4.3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme Y_phosphatase PF00102.25 001131618.1_43529001_1 - 7.5e-69 231.7 0.3 1e-68 231.3 0.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.18 001131618.1_43529001_1 - 4.3e-06 26.4 0.1 7.3e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.4 001131618.1_43529001_1 - 0.00023 21.0 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.4 001131618.1_43529001_1 - 0.0018 18.3 0.1 0.0033 17.5 0.1 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate PDZ PF00595.22 001131618.1_43529001_2 - 1.4e-19 70.1 0.0 2.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FERM_C PF09380.8 001131618.1_43529001_3 - 8.6e-24 83.6 1.4 1.6e-23 82.8 1.4 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.8 001131618.1_43529001_3 - 4.5e-17 61.6 0.0 8.2e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.16 001131618.1_43529001_3 - 9.6e-06 25.9 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 FERM central domain SH3_1 PF00018.26 001134141.1_43525001_1 - 9.4e-27 92.2 0.0 5.4e-15 54.6 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 001134141.1_43525001_1 - 5e-23 80.6 0.1 1.6e-12 46.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.15 001134141.1_43525001_1 - 1.7e-19 69.1 0.3 2.1e-12 46.4 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain TPR_1 PF00515.26 001134141.1_43525001_1 - 3.1e-14 52.0 7.1 1.5e-05 24.5 1.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.15 001134141.1_43525001_1 - 3.2e-14 51.7 4.1 0.00024 20.8 0.6 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.4 001134141.1_43525001_1 - 1.4e-10 40.4 4.8 0.0019 18.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.22 001134141.1_43525001_1 - 1.7e-10 40.5 0.1 3.7e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.4 001134141.1_43525001_1 - 8.4e-08 32.3 1.9 7.1e-05 22.9 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.4 001134141.1_43525001_1 - 4.7e-06 27.0 0.6 0.19 12.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.4 001134141.1_43525001_1 - 0.00046 19.9 0.2 5.7 6.8 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.4 001134141.1_43525001_1 - 0.0016 18.5 0.2 0.14 12.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.4 001134141.1_43525001_1 - 0.0037 17.3 0.1 0.034 14.2 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.4 001134141.1_43525001_1 - 0.16 11.6 1.9 0.59 9.7 0.4 2.6 2 1 0 2 2 2 0 TPR repeat TPR_7 PF13176.4 001134141.1_43525001_1 - 0.19 11.7 0.4 75 3.6 0.4 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.4 001134141.1_43525001_1 - 0.25 11.9 6.5 2.7 8.7 0.5 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Med12-LCEWAV PF12145.6 001131081.2_43529001_3 - 4.5e-181 602.7 20.6 8.1e-181 601.8 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain Med12-PQL PF12144.6 001131081.2_43529001_3 - 1.1e-57 195.2 29.2 3.1e-46 157.7 16.4 4.9 3 2 2 5 5 5 2 Eukaryotic Mediator 12 catenin-binding domain Med12 PF09497.8 001131081.2_43529001_3 - 1.5e-14 53.9 0.1 3.3e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 PA26 PF04636.11 001131081.2_43529001_3 - 4 6.1 21.7 6.9 5.3 21.7 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PDEase_I PF00233.17 001134151.1_43525001_2 - 2.9e-77 259.5 0.7 3.9e-77 259.0 0.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MANEC PF07502.12 001159799.1_43529001_1 - 1.8e-18 66.4 3.1 3e-18 65.7 3.1 1.4 1 0 0 1 1 1 1 MANEC domain DUF2370 PF10176.7 001132776.2_43529001_1 - 1.5e-06 27.9 1.0 0.00075 19.1 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) Lipin_N PF04571.12 001131435.1_43529001_1 - 7.5e-43 144.6 0.0 1.1e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 lipin, N-terminal conserved region LNS2 PF08235.11 001131435.1_43529001_1 - 3.4e-33 114.9 0.0 1.5e-30 106.2 0.0 2.1 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) WRNPLPNID PF15017.4 001131435.1_43529001_1 - 0.0022 18.7 1.4 0.0038 18.0 0.1 2.1 2 0 0 2 2 2 1 Putative WW-binding domain and destruction box Lipin_mid PF16876.3 001131435.1_43529001_2 - 9.1e-17 61.0 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain LNS2 PF08235.11 001131435.1_43529001_3 - 4.6e-55 186.4 0.0 6.8e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) RRM_1 PF00076.20 001133159.1_43526001_1 - 4.7e-43 144.7 0.5 2.3e-15 56.0 0.3 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.3 001133159.1_43526001_1 - 1.5e-09 37.7 0.1 0.043 13.8 0.0 4.0 2 2 1 3 3 3 3 RNA recognition motif RRM_5 PF13893.4 001133159.1_43526001_1 - 2.4e-05 23.8 0.0 5.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001133159.1_43526001_1 - 0.0077 15.9 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf-H2C2_2 PF13465.4 001133510.1_43527001_2 - 1.7e-53 176.6 88.6 8.1e-10 38.6 0.6 12.2 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2 PF00096.24 001133510.1_43527001_2 - 4.1e-48 159.1 92.8 4.7e-06 26.6 1.2 10.0 10 0 0 10 10 10 9 Zinc finger, C2H2 type SCAN PF02023.15 001133510.1_43527001_2 - 5.7e-40 134.9 2.8 1.1e-39 134.0 2.8 1.4 1 0 0 1 1 1 1 SCAN domain zf-C2H2_4 PF13894.4 001133510.1_43527001_2 - 1.5e-25 87.5 87.1 0.0017 18.9 0.5 10.3 11 0 0 11 11 9 9 C2H2-type zinc finger KRAB PF01352.25 001133510.1_43527001_2 - 6.9e-13 47.9 0.1 1.3e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_11 PF16622.3 001133510.1_43527001_2 - 2.1e-07 30.5 59.7 0.0014 18.3 2.7 9.3 9 0 0 9 9 9 5 zinc-finger C2H2-type Zn-ribbon_8 PF09723.8 001133510.1_43527001_2 - 4.3e-06 26.6 40.7 0.0017 18.3 3.0 7.1 5 1 2 7 7 7 4 Zinc ribbon domain zf-C2H2_6 PF13912.4 001133510.1_43527001_2 - 2.7e-05 23.9 66.8 0.0029 17.4 0.8 9.7 9 0 0 9 9 9 3 C2H2-type zinc finger zinc_ribbon_15 PF17032.3 001133510.1_43527001_2 - 0.096 13.3 32.2 0.58 10.8 0.9 5.2 3 2 2 5 5 5 0 zinc-ribbon family ADK_lid PF05191.12 001133510.1_43527001_2 - 1.7 8.6 30.3 3.6 7.6 0.2 6.5 6 2 1 7 7 7 0 Adenylate kinase, active site lid C1_4 PF07975.10 001133510.1_43527001_2 - 5.8 7.1 38.3 0.44 10.7 2.3 6.1 4 1 2 6 6 6 0 TFIIH C1-like domain BolA PF01722.16 001133510.1_43527001_2 - 7.3 6.8 14.9 4.5 7.5 0.5 4.2 4 1 1 5 5 5 0 BolA-like protein Translin PF01997.14 038093.1_43526120_2 - 4.1e-53 180.3 0.1 5.5e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 Translin family ODR4-like PF14778.4 024161.1_43525120_2 - 2.8e-52 177.7 0.2 2.5e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 Olfactory receptor 4-like ODR4-like PF14778.4 024161.1_43525120_3 - 2.4e-56 191.1 2.1 3.4e-56 190.6 2.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like bZIP_Maf PF03131.15 001131722.1_43524001_3 - 3.2e-17 62.7 4.8 6.7e-17 61.7 4.8 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.19 001131722.1_43524001_3 - 2.6e-07 30.5 10.3 2.6e-07 30.5 10.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.13 001131722.1_43524001_3 - 0.0031 17.4 12.2 0.0031 17.4 12.2 2.1 2 0 0 2 2 2 1 Basic region leucine zipper Peptidase_Mx PF15887.3 001131722.1_43524001_3 - 0.031 13.6 0.1 0.061 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase DNA_mis_repair PF01119.17 001131402.1_43529001_2 - 1.1e-10 41.1 0.0 2.8e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.4 001131402.1_43529001_2 - 2.3e-06 27.4 0.1 5.5e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.24 001131402.1_43529001_2 - 4.2e-06 27.2 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SapB_1 PF05184.13 001133580.1_43526001_1 - 1.8e-46 155.5 22.9 9.2e-14 51.0 0.8 4.8 4 0 0 4 4 4 4 Saposin-like type B, region 1 SapB_2 PF03489.15 001133580.1_43526001_1 - 1.4e-40 136.9 27.6 3.3e-11 43.0 0.9 5.4 5 0 0 5 5 5 4 Saposin-like type B, region 2 SapA PF02199.13 001133580.1_43526001_1 - 1.9e-29 101.3 34.9 1.8e-16 59.8 11.0 4.1 6 0 0 6 6 6 2 Saposin A-type domain Helicase_C_3 PF13625.4 001133580.1_43526001_1 - 0.17 11.9 0.0 0.59 10.2 0.0 1.8 2 0 0 2 2 2 0 Helicase conserved C-terminal domain zf-DBF PF07535.10 001133580.1_43526001_1 - 0.93 9.5 4.8 21 5.2 0.1 3.3 3 0 0 3 3 3 0 DBF zinc finger RNA_polI_A34 PF08208.9 001133580.1_43526001_2 - 2 8.3 33.1 2.9 7.8 33.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TruD PF01142.16 001133464.1_43527001_2 - 7.5e-15 54.5 0.0 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) TruD PF01142.16 001133464.1_43527001_3 - 5.4e-45 153.8 0.1 7.6e-40 136.9 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) XPG_I_2 PF12813.5 001133464.1_43527001_3 - 0.088 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 XPG domain containing R3H PF01424.20 001133464.1_43527001_3 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 R3H domain MARVEL PF01284.21 001135469.1_43525001_3 - 4.3e-28 98.0 4.0 4.3e-28 98.0 4.0 2.5 2 0 0 2 2 2 1 Membrane-associating domain DUF1129 PF06570.9 001135469.1_43525001_3 - 0.051 12.9 0.2 0.65 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF588 PF04535.10 001135469.1_43525001_3 - 0.17 11.5 8.6 0.039 13.6 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF588) Alg6_Alg8 PF03155.13 001132541.1_43524001_1 - 4.5e-145 484.1 27.1 5.4e-145 483.8 27.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyco_transf_25 PF01755.15 001131781.1_43529001_3 - 9.6e-41 139.7 0.0 5.1e-40 137.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.4 001131781.1_43529001_3 - 4.5e-17 62.2 0.3 1.1e-16 61.0 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Anp1 PF03452.12 001131781.1_43529001_3 - 0.00011 21.6 0.0 0.0066 15.8 0.0 2.2 1 1 0 1 1 1 1 Anp1 AP3D1 PF06375.9 001131849.1_43525001_2 - 0.16 12.1 11.3 0.23 11.6 11.3 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Rad51 PF08423.9 001131849.1_43525001_3 - 8e-24 84.2 0.3 1.2e-23 83.6 0.3 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.4 001131849.1_43525001_3 - 4.1e-12 46.0 0.8 6.2e-12 45.4 0.8 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.11 001131849.1_43525001_3 - 1.4e-08 34.3 0.5 3.3e-08 33.0 0.6 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.13 001131849.1_43525001_3 - 5.5e-08 32.3 0.5 2.9e-07 29.9 0.5 1.9 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.19 001131849.1_43525001_3 - 0.00037 19.9 1.0 0.031 13.6 0.1 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_24 PF13479.4 001131849.1_43525001_3 - 0.0022 17.6 0.0 0.0076 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain HHH_5 PF14520.4 001131849.1_43525001_3 - 0.0035 17.8 0.2 1.4 9.5 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.4 001131849.1_43525001_3 - 0.0064 16.6 0.2 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.4 001131849.1_43525001_3 - 0.0098 16.1 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sipho_Gp37 PF14594.4 001131849.1_43525001_3 - 0.014 14.2 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein AAA_5 PF07728.12 001131849.1_43525001_3 - 0.021 14.7 0.1 0.048 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.27 001131849.1_43525001_3 - 0.083 13.2 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiG_N PF11760.6 001131849.1_43525001_3 - 0.094 12.6 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal GvpD PF07088.9 001131849.1_43525001_3 - 0.11 10.9 0.0 0.2 10.1 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein PAXNEB PF05625.9 001131849.1_43525001_3 - 0.11 11.5 1.7 0.48 9.4 0.5 2.1 2 0 0 2 2 2 0 PAXNEB protein tRNA-synt_2 PF00152.18 001133290.1_43526001_3 - 2e-90 302.9 0.0 2e-89 299.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.23 001133290.1_43526001_3 - 8.9e-09 35.1 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.12 001133290.1_43526001_3 - 6e-07 29.5 0.0 0.00013 22.0 0.0 2.3 1 1 1 2 2 2 2 GAD domain Pyr_redox_2 PF07992.12 001135443.1_43525001_2 - 7.2e-56 189.4 5.0 5.8e-55 186.5 2.5 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.20 001135443.1_43525001_2 - 1.1e-41 141.3 0.4 2.5e-41 140.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.25 001135443.1_43525001_2 - 2.6e-16 59.8 6.9 3.8e-15 56.1 1.3 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.5 001135443.1_43525001_2 - 6.5e-09 35.5 0.0 6.5e-09 35.5 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.4 001135443.1_43525001_2 - 2.3e-07 30.8 2.2 0.00011 22.2 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.20 001135443.1_43525001_2 - 4.5e-07 29.2 3.7 1.3e-06 27.7 0.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.22 001135443.1_43525001_2 - 1.4e-06 27.6 0.3 1.4e-06 27.6 0.3 2.6 3 0 0 3 3 2 2 FAD binding domain Pyr_redox_3 PF13738.4 001135443.1_43525001_2 - 0.00014 21.1 2.6 0.22 10.6 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.19 001135443.1_43525001_2 - 0.00018 20.7 5.4 0.055 12.6 0.9 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.12 001135443.1_43525001_2 - 0.0002 20.0 6.2 0.0024 16.5 0.5 2.6 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.17 001135443.1_43525001_2 - 0.0011 18.1 4.7 0.018 14.2 0.2 3.0 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.15 001135443.1_43525001_2 - 0.0045 16.1 0.4 0.0085 15.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.12 001135443.1_43525001_2 - 0.16 11.4 5.0 1.9 7.9 0.2 2.7 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.22 001135443.1_43525001_2 - 0.19 11.2 4.0 3.8 6.9 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase 3HCDH_N PF02737.16 001135443.1_43525001_2 - 2.1 8.1 7.0 3 7.6 0.6 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Humanin PF15040.4 001193596.2_39723001_1 - 1.2e-15 56.6 0.1 1.9e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Humanin family DDE_Tnp_1_7 PF13843.4 001243897.1_39727001_1 - 4e-102 342.0 0.1 5.7e-102 341.5 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 SCAN PF02023.15 001243897.1_39727001_1 - 1.1e-38 130.7 1.7 2.3e-38 129.7 1.7 1.6 1 0 0 1 1 1 1 SCAN domain Gla PF00594.18 001243096.1_39722001_1 - 3e-20 72.0 9.2 7.8e-20 70.7 9.2 1.8 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain RCR PF12273.6 001243096.1_39722001_1 - 0.087 13.3 0.4 0.15 12.6 0.4 1.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.8 001243096.1_39722001_1 - 8.5 5.7 9.8 16 4.9 9.8 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-H2C2_2 PF13465.4 001135618.2_39725001_1 - 2.5e-122 394.2 104.6 1.1e-08 35.0 0.2 17.6 18 0 0 18 18 17 16 Zinc-finger double domain zf-C2H2 PF00096.24 001135618.2_39725001_1 - 1.3e-98 318.1 122.8 4.9e-07 29.7 0.4 18.0 18 0 0 18 18 17 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001135618.2_39725001_1 - 2.6e-51 167.7 116.5 0.0013 19.3 1.3 17.6 17 0 0 17 17 17 16 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001135618.2_39725001_1 - 4.9e-32 109.2 98.3 0.0014 18.4 1.0 17.6 17 0 0 17 17 17 14 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001135618.2_39725001_1 - 9.8e-20 70.3 80.0 0.0023 17.9 2.3 11.8 6 4 8 14 14 13 11 Zinc ribbon domain zf-C2H2_jaz PF12171.6 001135618.2_39725001_1 - 5.3e-19 67.9 65.2 0.18 12.0 1.6 17.0 17 0 0 17 17 17 5 Zinc-finger double-stranded RNA-binding XPA_N PF01286.16 001135618.2_39725001_1 - 7.6e-17 60.9 59.7 2.6 8.0 0.2 17.2 17 0 0 17 17 17 4 XPA protein N-terminal zinc_ribbon_15 PF17032.3 001135618.2_39725001_1 - 5.3e-10 39.8 64.3 0.44 11.2 4.5 9.3 1 1 11 13 13 13 11 zinc-ribbon family zf-LYAR PF08790.9 001135618.2_39725001_1 - 1.9e-08 33.9 75.2 0.19 11.5 0.7 16.3 17 0 0 17 17 17 5 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.3 001135618.2_39725001_1 - 0.0001 21.8 91.6 0.054 13.1 0.6 16.1 17 0 0 17 17 17 6 zinc-finger C2H2-type YhfH PF14149.4 001135618.2_39725001_1 - 0.00086 19.1 64.8 11 5.9 0.1 16.6 17 0 0 17 17 17 0 YhfH-like protein PknG_rubred PF16919.3 001135618.2_39725001_1 - 0.0028 17.6 51.5 0.34 10.9 0.6 9.5 2 2 9 11 11 11 3 Protein kinase G rubredoxin domain MRP-S23 PF10484.7 001135618.2_39725001_1 - 0.0034 17.5 0.0 40 4.3 0.0 6.1 7 2 1 8 8 5 0 Mitochondrial ribosomal protein S23 zf-trcl PF13451.4 001135618.2_39725001_1 - 0.075 12.8 67.8 8.3 6.3 0.1 15.7 15 2 0 15 15 15 0 Probable zinc-ribbon domain zf-met PF12874.5 001135618.2_39725001_1 - 0.089 13.1 0.2 0.089 13.1 0.2 16.6 17 0 0 17 17 17 0 Zinc-finger of C2H2 type ADK_lid PF05191.12 001135618.2_39725001_1 - 0.38 10.7 53.0 0.85 9.6 0.2 11.0 4 2 7 11 11 10 0 Adenylate kinase, active site lid DUF3268 PF11672.6 001135618.2_39725001_1 - 1.4 9.1 51.2 2.7 8.2 1.0 8.4 3 1 4 10 10 10 0 zinc-finger-containing domain Zn_ribbon_recom PF13408.4 001135618.2_39725001_1 - 1.4 9.3 71.9 19 5.7 0.6 12.8 5 3 4 9 9 8 0 Recombinase zinc beta ribbon domain HypA PF01155.17 001135618.2_39725001_1 - 3.8 7.4 66.9 0.49 10.3 1.3 9.5 2 1 10 12 12 11 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.8 001135618.2_39725001_1 - 3.9 8.1 41.8 30 5.2 1.8 12.6 3 2 11 14 14 13 0 Protein of unknown function (FYDLN_acid) zf-C2HE PF16278.3 001135618.2_39725001_1 - 6.8 7.1 89.6 4.6 7.6 0.0 16.4 4 2 12 16 16 16 0 C2HE / C2H2 / C2HC zinc-binding finger HRG PF16954.3 001243955.1_39727001_1 - 3.6e-23 81.6 14.0 4.7e-17 62.0 6.1 2.6 2 0 0 2 2 2 2 Haem-transporter, endosomal/lysosomal, haem-responsive gene 7tm_1 PF00001.19 001243955.1_39727001_1 - 0.62 9.1 6.3 1.1 8.3 6.3 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SNARE_assoc PF09335.9 001242611.1_39725001_1 - 2.3e-08 34.4 0.0 7e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 SNARE associated Golgi protein RSRP PF17069.3 001251891.1_39723001_3 - 9.6e-133 442.2 78.0 8.1e-124 412.9 76.1 2.1 2 0 0 2 2 2 2 Arginine/Serine-Rich protein 1 WD40 PF00400.30 001243972.1_39724001_2 - 1.3e-26 92.2 21.4 2.7e-06 27.9 0.4 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001243972.1_39724001_2 - 6.1e-20 71.2 8.0 1.4e-06 28.4 0.2 5.2 3 2 1 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001243972.1_39724001_2 - 1.6e-07 31.3 0.0 0.0027 17.4 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001243972.1_39724001_2 - 0.00026 19.9 0.5 0.035 12.9 0.2 3.5 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.3 001243972.1_39724001_2 - 0.061 11.8 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Cadherin PF00028.15 001082569.1_39729001_1 - 8.1e-82 269.7 0.0 3.1e-19 69.1 0.1 6.3 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.10 001082569.1_39729001_1 - 8.1e-31 105.5 0.0 2.6e-27 94.3 0.1 3.8 4 0 0 4 4 4 2 Cadherin-like Cadherin_tail PF15974.3 001082569.1_39729001_1 - 2e-25 89.6 3.3 4e-25 88.6 3.3 1.5 1 0 0 1 1 1 1 Cadherin C-terminal cytoplasmic tail, catenin-binding region Cadherin_C_2 PF16492.3 001082569.1_39729001_1 - 4.9e-24 84.8 0.4 1.2e-23 83.5 0.2 1.9 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal Cadherin_3 PF16184.3 001082569.1_39729001_1 - 8.9e-07 28.8 1.4 0.94 9.4 0.0 5.4 4 1 2 6 6 6 2 Cadherin-like DUF4939 PF16297.3 001243967.1_39729001_1 - 6.4e-10 38.8 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Tr-sialidase_C PF11052.6 001243967.1_39729001_3 - 0.0081 16.2 7.3 0.031 14.4 7.3 2.1 1 0 0 1 1 1 1 Trans-sialidase of Trypanosoma hydrophobic C-terminal E2F_CC-MB PF16421.3 001242344.1_39727001_2 - 1.2e-31 108.8 0.5 2e-31 108.2 0.5 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.18 001242344.1_39727001_2 - 5.6e-23 80.6 0.2 1.5e-22 79.2 0.1 1.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.17 001242344.1_39727001_2 - 0.09 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MGC-24 PF05283.9 001243958.1_39728001_2 - 2.4e-09 37.7 8.7 2.4e-09 37.7 8.7 2.3 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ribosomal_L29e PF01779.15 001251939.1_39722001_2 - 9.8e-26 89.7 8.4 9.8e-26 89.7 8.4 2.6 2 1 0 2 2 2 1 Ribosomal L29e protein family MAP1B_neuraxin PF00414.15 001194920.1_39729001_3 - 2.3e-42 140.7 113.0 6.1e-06 25.4 3.4 11.9 11 0 0 11 11 11 10 Neuraxin and MAP1B repeat Trypsin PF00089.24 001204058.1_39723001_3 - 1.6e-58 198.0 0.1 2.7e-58 197.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.9 001204058.1_39723001_3 - 0.081 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Phage_terminase PF10668.7 001204058.1_39723001_3 - 0.093 12.6 1.5 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 Phage terminase small subunit Homeobox PF00046.27 001135623.2_39723001_1 - 9.8e-21 73.2 5.8 2e-20 72.2 5.8 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001135623.2_39723001_1 - 0.047 13.5 0.3 0.047 13.5 0.3 2.1 2 0 0 2 2 2 0 Homeobox KN domain DUF4712 PF15830.3 001251839.1_39724001_1 - 4.4e-142 472.0 3.4 5.4e-142 471.7 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4712) HAT_KAT11 PF08214.9 001244670.1_39729001_1 - 1.8e-70 237.9 0.2 3.4e-70 236.9 0.2 1.4 1 0 0 1 1 1 1 Histone acetylation protein KIX PF02172.14 001244670.1_39729001_1 - 2.6e-40 136.4 1.1 5e-40 135.5 1.1 1.5 1 0 0 1 1 1 1 KIX domain Creb_binding PF09030.8 001244670.1_39729001_1 - 1.9e-33 115.3 15.4 1.9e-33 115.3 15.4 11.7 9 3 2 11 11 11 1 Creb binding zf-TAZ PF02135.14 001244670.1_39729001_1 - 2.1e-28 98.5 72.2 5e-19 68.4 21.3 3.8 3 0 0 3 3 3 2 TAZ zinc finger DUF902 PF06001.11 001244670.1_39729001_1 - 7.3e-22 77.4 7.7 7.3e-22 77.4 7.7 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.23 001244670.1_39729001_1 - 1.9e-16 59.7 0.1 4.3e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.15 001244670.1_39729001_1 - 7.9e-15 54.3 14.7 7.9e-15 54.3 14.7 3.2 3 0 0 3 3 3 1 Zinc finger, ZZ type KIX_2 PF16987.3 001244670.1_39729001_1 - 0.0001 22.1 0.4 0.0003 20.6 0.4 1.9 1 0 0 1 1 1 1 KIX domain Npa1 PF11707.6 001244670.1_39729001_1 - 0.0006 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal EPL1 PF10513.7 001244670.1_39729001_1 - 0.019 15.2 9.0 1.4 9.2 1.3 3.0 2 0 0 2 2 2 0 Enhancer of polycomb-like Apo-CII PF05355.9 001243899.1_39721001_1 - 3.8e-43 145.3 0.9 4.5e-43 145.1 0.9 1.0 1 0 0 1 1 1 1 Apolipoprotein C-II Reticulon PF02453.15 001048049.2_39729001_3 - 1.7e-42 144.9 10.9 2.8e-42 144.2 10.9 1.3 1 0 0 1 1 1 1 Reticulon Ig_3 PF13927.4 001302657.1_39722001_1 - 1.9e-07 31.4 0.2 0.0021 18.5 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001302657.1_39722001_1 - 4.4e-07 29.9 0.0 1.2e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.4 001302657.1_39722001_1 - 1.2e-05 25.4 0.5 0.12 12.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001302657.1_39722001_1 - 9e-05 22.4 0.2 0.91 9.6 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001302657.1_39722001_1 - 0.0022 17.9 0.0 0.094 12.7 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin I-set domain Latrophilin PF02354.14 001261704.1_29629001_1 - 4e-116 388.0 22.5 1.2e-84 284.4 6.9 2.2 1 1 1 2 2 2 2 Latrophilin Cytoplasmic C-terminal region OLF PF02191.14 001261704.1_29629001_1 - 3.6e-84 282.1 5.1 6.6e-84 281.2 5.1 1.5 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_2 PF00002.22 001261704.1_29629001_1 - 8.7e-70 234.7 19.3 1.2e-69 234.2 19.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.3 001261704.1_29629001_1 - 1.2e-53 181.5 2.6 1.8e-53 180.9 2.6 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.16 001261704.1_29629001_1 - 1.7e-23 82.7 0.7 1.7e-23 82.7 0.7 2.1 2 0 0 2 2 2 1 Galactose binding lectin domain GPS PF01825.19 001261704.1_29629001_1 - 5e-15 55.7 6.7 1.2e-14 54.5 6.7 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.20 001261704.1_29629001_1 - 5.2e-06 26.5 0.5 1.6e-05 25.0 0.5 1.9 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.9 001261704.1_29629001_1 - 0.0071 15.4 15.2 0.013 14.6 15.2 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Pox_A14 PF05767.10 001261704.1_29629001_1 - 0.99 9.5 5.0 2.7 8.1 1.7 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 UDPGT PF00201.16 001172143.1_40424001_2 - 6.8e-258 856.3 0.8 8e-258 856.0 0.8 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001172143.1_40424001_2 - 2.1e-07 31.0 0.0 3.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.4 001172143.1_40424001_2 - 0.00016 21.6 0.0 0.0013 18.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.4 001172143.1_40424001_2 - 0.015 15.6 0.0 0.039 14.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Ras PF00071.20 001163596.1_39522001_1 - 5.4e-46 156.0 0.0 6.6e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001163596.1_39522001_1 - 2.9e-20 72.6 0.0 4.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001163596.1_39522001_1 - 0.00022 20.6 0.0 0.00039 19.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001163596.1_39522001_1 - 0.0025 17.7 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 7tm_2 PF00002.22 001243056.1_49828001_1 - 1.3e-27 96.5 17.5 1.9e-27 96.0 17.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.19 001243056.1_49828001_1 - 8.3e-13 48.6 2.4 8.3e-13 48.6 2.4 2.5 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif 7tm_1 PF00001.19 001285612.1_09023001_2 - 1.1e-40 139.5 12.1 1.1e-40 139.5 12.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CHORD PF04968.10 001257756.1_29626001_3 - 1.9e-54 182.1 16.1 2.1e-28 98.6 2.4 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.14 001257756.1_29626001_3 - 2.3e-13 50.8 0.2 4.9e-13 49.8 0.2 1.6 1 0 0 1 1 1 1 CS domain BTK PF00779.17 001257756.1_29626001_3 - 0.027 14.2 5.1 2.2 8.1 0.4 3.0 2 0 0 2 2 2 0 BTK motif Exo_endo_phos PF03372.21 001079688.1_32322001_1 - 6.5e-07 29.5 0.0 8.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.4 001079688.1_32322001_1 - 0.14 11.9 0.0 1.3 8.8 0.0 2.4 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase Thioredoxin PF00085.18 001168820.1_40423001_1 - 3.4e-50 168.2 0.0 3.6e-25 87.8 0.1 3.3 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.4 001168820.1_40423001_1 - 6.7e-45 153.2 0.0 1.4e-35 122.8 0.0 3.0 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.11 001168820.1_40423001_1 - 1.6e-11 44.0 0.0 0.00092 18.5 0.0 3.2 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 001168820.1_40423001_1 - 4.1e-08 33.5 0.1 0.017 15.4 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001168820.1_40423001_1 - 3.6e-05 23.9 0.0 0.012 15.8 0.0 4.0 4 1 1 5 5 5 1 Thioredoxin-like AhpC-TSA PF00578.19 001168820.1_40423001_1 - 4.6e-05 23.2 0.2 0.002 17.9 0.1 2.4 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.4 001168820.1_40423001_1 - 6.4e-05 22.9 0.1 0.093 12.8 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin-like Redoxin PF08534.8 001168820.1_40423001_1 - 0.023 14.2 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 Redoxin TraF PF13728.4 001168820.1_40423001_1 - 0.028 14.1 0.1 1.7 8.3 0.0 3.3 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.4 001168820.1_40423001_1 - 0.076 12.9 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain DUF1798 PF08807.8 001168820.1_40423001_1 - 0.087 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Pro_dh PF01619.16 001168820.1_40423001_1 - 0.21 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Proline dehydrogenase Pkinase PF00069.23 001166317.2_49824001_2 - 1.2e-77 260.8 0.0 1.5e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001166317.2_49824001_2 - 3.9e-30 104.9 0.0 5.5e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001166317.2_49824001_2 - 8.5e-06 25.2 0.0 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.21 001166317.2_49824001_2 - 0.0018 18.1 6.5 0.03 14.1 0.1 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.12 001166317.2_49824001_2 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001166317.2_49824001_2 - 0.064 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.9 001166317.2_49824001_2 - 0.072 11.9 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.18 001166317.2_49824001_2 - 0.13 11.7 0.5 0.44 10.0 0.1 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Neurokinin_B PF03823.12 001287572.1_09022001_3 - 5.8e-34 115.7 0.1 1.3e-33 114.6 0.1 1.7 1 0 0 1 1 1 1 Neurokinin B Pou PF00157.15 001242727.1_37623001_1 - 1.4e-36 124.2 0.3 2.5e-36 123.4 0.3 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001242727.1_37623001_1 - 1.1e-19 69.8 1.1 6.8e-18 64.1 0.3 2.3 2 0 0 2 2 2 2 Homeobox domain HTH_31 PF13560.4 001242727.1_37623001_1 - 0.024 14.8 0.2 0.29 11.4 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain DUF521 PF04412.11 001242727.1_37623001_1 - 0.071 11.7 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) LEAP-2 PF07359.9 001171258.1_37921001_1 - 1.1e-45 153.2 3.1 1.2e-45 153.1 3.1 1.0 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EB PF01683.16 001171258.1_37921001_1 - 0.0047 17.0 0.2 0.0048 17.0 0.2 1.1 1 0 0 1 1 1 1 EB module OAS1_C PF10421.7 001083949.1_29624001_1 - 4.8e-87 290.1 0.3 6.4e-87 289.7 0.3 1.1 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.21 001083949.1_29624001_1 - 2.8e-08 33.8 0.0 5.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Tcp11 PF05794.11 001194784.1_29626001_1 - 2.1e-109 366.4 0.0 2.7e-109 366.0 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 11 UDPGT PF00201.16 001112624.2_40424001_2 - 2.9e-239 794.8 0.1 3.3e-239 794.6 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001112624.2_40424001_2 - 1.6e-08 34.6 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PAS_3 PF08447.10 001082782.1_37925001_3 - 4e-28 97.4 0.2 1.4e-21 76.4 0.1 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.4 001082782.1_37925001_3 - 1e-22 80.2 0.8 6.6e-20 71.2 0.1 2.5 2 0 0 2 2 2 2 PAS domain HIF-1a_CTAD PF08778.8 001082782.1_37925001_3 - 2.7e-22 78.0 0.5 5.7e-22 76.9 0.5 1.6 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.6 001082782.1_37925001_3 - 1.1e-15 56.6 6.3 2.6e-15 55.4 6.3 1.7 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 PAS PF00989.23 001082782.1_37925001_3 - 1.1e-15 57.5 0.0 3.3e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.5 001082782.1_37925001_3 - 4.9e-10 39.5 0.0 0.00053 20.1 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.8 001082782.1_37925001_3 - 2.1e-07 31.0 0.0 0.0081 16.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.24 001082782.1_37925001_3 - 0.029 14.2 0.1 0.064 13.1 0.1 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DDRGK PF09756.7 001082782.1_37925001_3 - 0.036 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 DDRGK domain UDPGT PF00201.16 001112625.2_40424001_1 - 2.2e-238 791.9 0.0 2.5e-238 791.7 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001112625.2_40424001_1 - 1.5e-08 34.7 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.16 001112620.2_40424001_2 - 1.3e-247 822.4 0.9 1.5e-247 822.2 0.9 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001112620.2_40424001_2 - 1.3e-08 34.9 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.4 001112620.2_40424001_2 - 0.00071 19.5 0.8 0.0052 16.7 0.8 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 UDPGT PF00201.16 001112658.1_40424001_1 - 1.3e-247 822.4 0.5 1.5e-247 822.2 0.5 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001112658.1_40424001_1 - 1.2e-08 35.0 0.0 2.8e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.4 001112658.1_40424001_1 - 7.5e-05 22.7 0.6 0.0013 18.7 0.6 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.4 001112658.1_40424001_1 - 0.017 15.0 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glyco_trans_4_4 PF13579.4 001112658.1_40424001_1 - 0.065 13.5 0.1 0.13 12.6 0.1 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.9 001112658.1_40424001_1 - 0.067 12.7 0.2 0.2 11.2 0.2 1.8 1 1 0 1 1 1 0 Starch synthase catalytic domain TNFR_c6 PF00020.16 001319273.1_40422001_1 - 1.1e-16 60.8 39.8 0.00015 22.0 2.3 4.5 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region TMEM154 PF15102.4 001319273.1_40422001_1 - 0.073 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family OAD_gamma PF04277.11 001319273.1_40422001_1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MHC_I PF00129.16 001114965.1_29623001_1 - 7.3e-29 100.4 3.2 2.2e-28 98.9 1.6 1.9 2 0 0 2 2 2 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001114965.1_29623001_1 - 2.9e-10 40.4 0.0 6.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001114965.1_29623001_1 - 0.00052 20.4 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.4 001114965.1_29623001_1 - 0.034 14.4 0.1 0.072 13.3 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain BTAD PF03704.15 001114965.1_29623001_1 - 0.19 12.0 2.8 11 6.3 0.1 3.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Tad PF13400.4 001114965.1_29623001_2 - 0.13 12.4 4.6 0.24 11.6 4.6 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like MotB_plug PF13677.4 001114965.1_29623001_2 - 0.49 9.9 3.1 0.96 9.0 3.1 1.4 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB UDPGT PF00201.16 001112622.2_40424001_1 - 3e-242 804.7 0.0 3.5e-242 804.5 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001112622.2_40424001_1 - 1.1e-08 35.0 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DAN PF03045.13 001266108.1_29623001_3 - 1.3e-40 137.8 9.9 1.6e-40 137.5 9.1 1.5 2 0 0 2 2 2 1 DAN domain Cys_knot PF00007.20 001266108.1_29623001_3 - 4.4e-05 23.6 6.2 8.5e-05 22.7 6.2 1.5 1 0 0 1 1 1 1 Cystine-knot domain TIR_2 PF13676.4 001266108.1_29623001_3 - 0.0023 18.1 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain Gal-bind_lectin PF00337.20 001161716.2_40421001_1 - 6e-31 106.6 0.0 6.8e-31 106.4 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin Fascin PF06268.11 001004232.1_45724001_3 - 2.6e-61 204.6 0.1 3.4e-27 94.7 0.2 4.9 4 1 1 5 5 5 4 Fascin domain FRG1 PF06229.10 001004232.1_45724001_3 - 3.1e-09 36.7 0.0 0.63 9.6 0.0 5.1 3 2 2 5 5 5 4 FRG1-like domain DUF569 PF04601.11 001004232.1_45724001_3 - 0.014 15.0 0.1 0.3 10.6 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF569) Sec7 PF01369.18 001261046.1_29629001_1 - 4.1e-70 235.1 0.5 1e-69 233.8 0.5 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.5 001261046.1_29629001_1 - 1.9e-50 170.8 3.6 1.9e-50 170.8 3.6 3.4 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.3 001261046.1_29629001_1 - 4.3e-43 146.9 0.3 4.3e-43 146.9 0.3 3.1 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.8 001261046.1_29629001_1 - 6.3e-36 122.0 0.2 6.3e-36 122.0 0.2 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) CH PF00307.29 001257919.2_29629001_1 - 7.7e-21 74.2 0.0 2.4e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.6 001257919.2_29629001_1 - 0.00015 21.4 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Prefoldin_2 PF01920.18 001257919.2_29629001_1 - 0.0054 16.5 14.3 0.0054 16.5 14.3 6.8 4 1 1 6 6 6 2 Prefoldin subunit Baculo_PEP_C PF04513.10 001257919.2_29629001_1 - 4.8 7.1 26.6 0.3 11.0 1.2 5.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_8 PF13855.4 001193792.1_29626001_1 - 1e-24 85.9 12.5 8.4e-14 51.0 3.2 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.4 001193792.1_29626001_1 - 1.4e-06 28.2 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_4 PF12799.5 001193792.1_29626001_1 - 3.5e-06 27.1 10.3 0.004 17.4 0.1 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001193792.1_29626001_1 - 0.024 14.0 0.2 0.09 12.1 0.1 1.8 1 1 1 2 2 2 0 Leucine-rich repeat fn3 PF00041.19 001193792.1_29626001_1 - 0.041 14.1 0.1 0.095 12.9 0.1 1.6 1 0 0 1 1 1 0 Fibronectin type III domain CD34_antigen PF06365.10 001193792.1_29626001_1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4552 PF15089.4 001193792.1_29626001_1 - 0.23 10.3 0.5 0.36 9.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) LRR_1 PF00560.31 001193792.1_29626001_1 - 0.63 10.6 2.7 41 5.1 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat Laminin_N PF00055.15 001329071.1_37929001_1 - 6e-48 163.3 0.0 6e-48 163.3 0.0 2.4 3 1 1 4 4 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.22 001329071.1_37929001_1 - 1.4e-46 156.2 123.1 5.4e-12 45.5 13.1 7.4 7 1 0 7 7 6 6 Laminin EGF domain ATG16 PF08614.9 001329071.1_37929001_1 - 0.0012 18.9 6.9 0.0012 18.9 6.9 4.4 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) Alanine_zipper PF11839.6 001329071.1_37929001_1 - 0.0039 17.3 2.7 0.0039 17.3 2.7 4.2 5 0 0 5 5 3 1 Alanine-zipper, major outer membrane lipoprotein Laminin_II PF06009.10 001329071.1_37929001_1 - 0.065 13.1 22.4 0.053 13.4 2.3 4.2 3 1 2 5 5 4 0 Laminin Domain II Mnd1 PF03962.13 001329071.1_37929001_1 - 0.084 12.6 18.0 0.19 11.4 4.5 3.3 3 0 0 3 3 3 0 Mnd1 family F5_F8_type_C PF00754.23 001329071.1_37929001_1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain BNR_6 PF15899.3 001329071.1_37929001_1 - 0.16 12.0 0.1 0.42 10.7 0.1 1.6 1 0 0 1 1 1 0 BNR-Asp box repeat Reo_sigmaC PF04582.10 001329071.1_37929001_1 - 0.19 10.9 10.4 5.4 6.2 0.1 3.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DASH_Duo1 PF08651.8 001329071.1_37929001_1 - 0.26 10.9 1.4 1.2 8.8 0.7 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 EzrA PF06160.10 001329071.1_37929001_1 - 0.41 8.6 12.0 0.64 8.0 0.6 2.6 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.9 001329071.1_37929001_1 - 0.88 8.3 21.7 0.39 9.4 2.1 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein Sec20 PF03908.11 001329071.1_37929001_1 - 1.1 9.1 8.4 6.8 6.5 0.1 3.9 3 0 0 3 3 3 0 Sec20 DUF948 PF06103.9 001329071.1_37929001_1 - 1.3 9.2 9.7 5.8 7.1 0.5 4.3 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.5 001329071.1_37929001_1 - 1.6 8.7 29.8 0.095 12.7 1.6 4.4 4 1 1 5 5 4 0 Tropomyosin like Leu_zip PF15294.4 001329071.1_37929001_1 - 1.9 7.8 16.9 0.063 12.7 0.7 3.3 2 1 1 3 3 3 0 Leucine zipper BLOC1S3 PF15753.3 001329071.1_37929001_1 - 2.4 8.1 7.3 6.6 6.7 0.1 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Fib_alpha PF08702.8 001329071.1_37929001_1 - 6 6.9 12.3 0.74 9.9 0.1 3.7 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Sec34 PF04136.13 001329071.1_37929001_1 - 6.4 6.5 12.3 2.1 8.1 1.4 3.7 4 0 0 4 4 4 0 Sec34-like family TMPIT PF07851.11 001329071.1_37929001_1 - 7.5 5.6 14.1 0.65 9.1 0.5 2.9 2 1 1 3 3 3 0 TMPIT-like protein BLOC1_2 PF10046.7 001329071.1_37929001_1 - 9.5 6.5 12.5 2.6 8.3 0.2 4.5 2 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hormone_1 PF00103.18 001290304.1_40422001_1 - 2.5e-61 207.0 0.2 3.2e-61 206.7 0.2 1.1 1 0 0 1 1 1 1 Somatotropin hormone family TGF_beta PF00019.18 001329069.1_37923001_1 - 1.5e-29 102.8 1.7 3.1e-29 101.8 1.7 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.16 001329069.1_37923001_1 - 5.9e-09 35.9 1.3 5.4e-08 32.8 1.3 2.2 1 1 0 1 1 1 1 TGF-beta propeptide UCH PF00443.27 027279.1_26223120_1 - 3.8e-48 164.1 1.1 4.8e-48 163.8 1.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 027279.1_26223120_1 - 5.9e-19 68.7 0.1 1.8e-18 67.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FAD_binding_2 PF00890.22 003266.2_26224120_1 - 1.7e-42 145.8 0.1 2.4e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Hormone_1 PF00103.18 001290352.1_08022001_3 - 4.8e-47 160.4 0.9 5.5e-47 160.2 0.9 1.0 1 0 0 1 1 1 1 Somatotropin hormone family HipA_C PF07804.10 001290352.1_08022001_3 - 0.068 13.1 0.1 4.7 7.2 0.0 2.2 2 0 0 2 2 2 0 HipA-like C-terminal domain CLTH PF10607.7 001290352.1_08022001_3 - 0.078 12.7 1.4 0.14 11.9 1.4 1.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Trp_leader1 PF08055.9 001290352.1_08022001_3 - 0.11 12.1 2.1 0.23 11.1 2.1 1.5 1 0 0 1 1 1 0 Tryptophan leader peptide Ank_2 PF12796.5 001205041.1_08025001_1 - 3.7e-53 177.9 1.9 3.7e-17 62.5 0.0 5.3 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001205041.1_08025001_1 - 1.1e-47 159.7 4.0 2.3e-09 37.4 0.0 7.3 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.28 001205041.1_08025001_1 - 1.4e-36 123.2 7.3 2.2e-06 27.7 0.0 10.1 8 3 2 10 10 10 7 Ankyrin repeat Ank_3 PF13606.4 001205041.1_08025001_1 - 2.6e-33 110.2 4.3 0.00012 22.1 0.0 10.1 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.4 001205041.1_08025001_1 - 8e-25 86.4 6.0 4.7e-06 26.7 0.2 7.5 3 1 4 8 8 8 5 Ankyrin repeats (many copies) SOCS_box PF07525.14 001205041.1_08025001_1 - 2.2e-11 43.8 4.7 4e-11 42.9 3.9 1.9 2 0 0 2 2 2 1 SOCS box Ribosomal_60s PF00428.17 001204128.1_08029001_2 - 4 7.9 10.1 9.5 6.7 10.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein AKAP2_C PF15304.4 001204128.1_08029001_3 - 8.3e-19 67.9 4.4 8.3e-19 67.9 4.4 2.7 2 1 0 2 2 2 1 A-kinase anchor protein 2 C-terminus SUIM_assoc PF16619.3 001204128.1_08029001_3 - 1.9 8.5 12.0 0.25 11.4 6.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Lectin_C PF00059.19 001257249.1_08022001_3 - 1.5e-19 70.6 2.1 3e-19 69.6 2.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.10 001257249.1_08022001_3 - 6.9e-06 25.7 5.0 1.3e-05 24.8 5.0 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001257249.1_08022001_3 - 0.0061 15.7 0.2 0.01 15.0 0.2 1.4 1 0 0 1 1 1 1 Chordopoxvirus A33R protein UL2 PF08196.9 001257249.1_08022001_3 - 0.14 12.0 0.3 0.28 11.1 0.3 1.4 1 0 0 1 1 1 0 UL2 protein p450 PF00067.20 001267768.1_08024001_1 - 6.8e-133 443.7 0.0 8.3e-133 443.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ig_2 PF13895.4 001267729.1_08023001_3 - 9.7e-21 73.8 3.0 5.3e-12 45.8 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001267729.1_08023001_3 - 1.7e-16 60.4 1.5 1e-08 35.5 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.3 001267729.1_08023001_3 - 5.3e-09 36.2 1.2 1.6e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ig PF00047.23 001267729.1_08023001_3 - 1.5e-08 34.5 4.1 0.00014 21.9 0.5 3.6 2 2 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001267729.1_08023001_3 - 1e-07 31.9 4.7 0.013 15.6 0.1 3.9 2 2 2 4 4 4 2 Immunoglobulin V-set domain Ig_4 PF16680.3 001267729.1_08023001_3 - 1.5e-07 31.5 0.7 0.0011 19.1 0.1 2.2 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain I-set PF07679.14 001267729.1_08023001_3 - 7e-06 25.9 2.0 0.058 13.3 0.1 2.9 2 2 0 2 2 2 2 Immunoglobulin I-set domain Adeno_E3_CR1 PF02440.13 001267729.1_08023001_3 - 0.0089 15.7 3.9 1.3 8.7 0.2 3.3 2 2 0 2 2 2 2 Adenovirus E3 region protein CR1 DUF3394 PF11874.6 001267729.1_08023001_3 - 0.015 14.8 0.1 0.031 13.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) ANAPC4_WD40 PF12894.5 001267729.1_08023001_3 - 0.059 13.6 0.1 3.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TadE PF07811.10 001267729.1_08023001_3 - 0.28 11.4 2.1 0.69 10.1 2.1 1.6 1 0 0 1 1 1 0 TadE-like protein CD4-extracel PF09191.8 001267772.1_08023001_1 - 7.6e-45 151.6 1.6 4.7e-44 149.0 0.2 2.7 2 0 0 2 2 2 1 CD4, extracellular C2-set PF05790.13 001267772.1_08023001_1 - 2.6e-39 133.1 8.3 5.7e-20 71.2 0.2 3.9 3 1 0 3 3 3 2 Immunoglobulin C2-set domain ig PF00047.23 001267772.1_08023001_1 - 2.9e-21 75.3 5.8 6.1e-18 64.7 0.1 4.2 4 1 0 4 4 4 2 Immunoglobulin domain Tcell_CD4_C PF12104.6 001267772.1_08023001_1 - 2.1e-17 62.6 8.8 2.1e-17 62.6 8.8 1.9 2 0 0 2 2 1 1 T cell CD4 receptor C terminal region V-set PF07686.15 001267772.1_08023001_1 - 3.8e-14 52.6 0.1 8.2e-10 38.7 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.14 001267772.1_08023001_1 - 1.7e-10 40.7 2.2 1.6e-05 24.7 0.4 4.5 4 2 1 5 5 5 2 Immunoglobulin I-set domain Ig_3 PF13927.4 001267772.1_08023001_1 - 4.5e-10 39.9 1.5 5.3e-06 26.8 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.4 001267772.1_08023001_1 - 5.9e-09 36.0 0.2 0.0018 18.4 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin domain Receptor_2B4 PF11465.6 001267772.1_08023001_1 - 0.004 17.2 0.6 0.02 15.0 0.2 2.3 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.3 001267772.1_08023001_1 - 0.011 15.6 0.0 3.1 7.8 0.0 2.9 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Herpes_gE PF02480.14 001267772.1_08023001_1 - 0.11 11.1 0.0 0.43 9.1 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E ATP1G1_PLM_MAT8 PF02038.14 001267772.1_08023001_1 - 0.73 9.1 4.3 0.16 11.3 0.3 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family ANAPC15 PF15243.4 001199361.2_08022001_1 - 7.8e-39 131.9 15.2 7.8e-39 131.9 15.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 DUF4746 PF15928.3 001199361.2_08022001_1 - 0.1 11.9 6.8 0.14 11.4 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.10 001199361.2_08022001_1 - 1.6 6.7 18.8 1.9 6.5 18.8 1.0 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.6 001199361.2_08022001_1 - 1.7 7.6 15.7 2.2 7.2 15.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RXT2_N PF08595.9 001199361.2_08022001_1 - 7.2 6.5 12.3 12 5.8 12.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal ANAPC15 PF15243.4 001282057.1_08022001_2 - 7.8e-39 131.8 15.2 7.8e-39 131.8 15.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 RNA_pol_3_Rpc31 PF11705.6 001282057.1_08022001_2 - 0.0015 18.7 12.3 0.0023 18.1 12.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF4746 PF15928.3 001282057.1_08022001_2 - 0.14 11.5 7.0 0.19 11.0 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.10 001282057.1_08022001_2 - 1.6 6.7 18.8 1.9 6.4 18.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.7 001282057.1_08022001_2 - 4.2 6.3 28.8 5.7 5.9 28.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid_p PF12226.6 001282057.1_08022001_2 - 4.9 6.1 17.2 6.7 5.6 17.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RXT2_N PF08595.9 001282057.1_08022001_2 - 7.2 6.5 12.3 12 5.8 12.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal ANAPC15 PF15243.4 001282058.1_08022001_2 - 7.3e-39 131.9 15.2 7.3e-39 131.9 15.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 DUF4746 PF15928.3 001282058.1_08022001_2 - 0.095 12.0 6.8 0.13 11.5 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.10 001282058.1_08022001_2 - 1.5 6.8 18.8 1.8 6.5 18.8 1.0 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.6 001282058.1_08022001_2 - 1.6 7.7 15.7 2 7.3 15.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2457 PF10446.7 001282058.1_08022001_2 - 3.9 6.4 28.8 5.3 5.9 28.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.12 001282058.1_08022001_2 - 7.2 4.6 16.7 9.3 4.3 16.7 1.0 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.8 001282058.1_08022001_2 - 9.4 4.5 14.4 12 4.1 14.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein ANAPC15 PF15243.4 001282059.1_08022001_2 - 6.3e-39 132.2 15.2 6.3e-39 132.2 15.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 RNA_pol_3_Rpc31 PF11705.6 001282059.1_08022001_2 - 0.00068 19.8 11.5 0.0011 19.1 11.5 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF4746 PF15928.3 001282059.1_08022001_2 - 0.072 12.4 6.4 0.1 11.9 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Na_trans_assoc PF06512.11 001282059.1_08022001_2 - 0.75 10.0 10.0 1 9.6 10.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.10 001282059.1_08022001_2 - 1.3 7.0 18.8 1.6 6.8 18.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.7 001282059.1_08022001_2 - 3.4 6.6 28.8 4.6 6.2 28.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid_p PF12226.6 001282059.1_08022001_2 - 4.2 6.3 17.3 5.5 5.9 17.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.12 001282059.1_08022001_2 - 8.1 4.5 17.0 10 4.1 17.0 1.0 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.8 001282059.1_08022001_2 - 8.3 4.7 14.4 10 4.4 14.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein EF-hand_1 PF00036.30 001270720.1_08026001_2 - 5.2e-24 81.8 13.9 1.2e-05 24.3 0.4 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.4 001270720.1_08026001_2 - 2.4e-23 82.3 2.2 8.1e-13 48.5 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.4 001270720.1_08026001_2 - 1.9e-18 64.9 8.3 0.00017 20.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.4 001270720.1_08026001_2 - 2.7e-18 64.2 7.5 0.00013 21.5 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.4 001270720.1_08026001_2 - 3.6e-15 55.3 8.0 0.0075 15.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001270720.1_08026001_2 - 1.4e-06 28.4 0.1 0.028 14.6 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001270720.1_08026001_2 - 5.6e-05 22.9 3.0 0.048 13.5 0.1 3.1 2 2 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.4 001270720.1_08026001_2 - 0.067 13.4 0.1 0.69 10.2 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain GSG-1 PF07803.9 001270902.1_08025001_1 - 3.5e-40 136.3 0.1 7e-40 135.4 0.1 1.5 1 0 0 1 1 1 1 GSG1-like protein PMP22_Claudin PF00822.18 001270902.1_08025001_1 - 6.3e-05 22.8 4.2 8.6e-05 22.3 2.2 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001270902.1_08025001_1 - 9.2e-05 22.1 1.0 0.00018 21.2 1.0 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction MACPF PF01823.17 001257251.1_08024001_1 - 5e-37 127.9 0.0 6.5e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 MAC/Perforin domain C2 PF00168.28 001257251.1_08024001_1 - 2.3e-11 43.8 0.0 5.2e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain zf-H2C2_2 PF13465.4 001270905.1_08029001_1 - 9.5e-94 303.9 95.0 6.3e-09 35.8 1.9 16.1 15 0 0 15 15 15 12 Zinc-finger double domain zf-C2H2 PF00096.24 001270905.1_08029001_1 - 3e-52 172.1 116.1 5.1e-06 26.5 0.9 15.6 15 0 0 15 15 15 13 Zinc finger, C2H2 type KRAB PF01352.25 001270905.1_08029001_1 - 3.7e-23 80.8 0.5 7e-23 79.9 0.5 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001270905.1_08029001_1 - 3.7e-15 55.2 125.8 0.014 16.0 0.9 16.6 16 0 0 16 16 16 11 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001270905.1_08029001_1 - 3.4e-08 33.3 62.6 0.047 13.7 2.1 8.9 5 2 3 9 9 9 6 Zinc ribbon domain zf-C2H2_6 PF13912.4 001270905.1_08029001_1 - 5.2e-07 29.3 89.2 0.06 13.2 1.0 14.4 14 0 0 14 14 14 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001270905.1_08029001_1 - 9.9e-07 28.8 61.0 0.67 10.2 0.1 12.9 13 0 0 13 13 13 6 Zinc-finger double-stranded RNA-binding XPA_N PF01286.16 001270905.1_08029001_1 - 3e-05 23.8 63.2 1.4 8.9 0.1 13.8 13 0 0 13 13 13 4 XPA protein N-terminal BolA PF01722.16 001270905.1_08029001_1 - 4.9 7.4 10.6 15 5.8 0.1 4.2 4 0 0 4 4 4 0 BolA-like protein zf-C2H2 PF00096.24 001270905.1_08029001_3 - 0.0024 18.1 1.3 0.012 15.9 1.3 2.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001270905.1_08029001_3 - 0.78 10.2 5.1 3.7 8.0 0.8 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Ig_2 PF13895.4 001257222.1_08023001_1 - 2.4e-07 30.9 0.9 4.1e-05 23.7 0.2 2.5 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 001257222.1_08023001_1 - 1.1e-06 28.6 0.8 4.2e-06 26.8 0.0 2.3 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001257222.1_08023001_1 - 9.8e-05 22.8 0.1 0.58 10.7 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain DUF3533 PF12051.6 001257222.1_08023001_1 - 0.00024 20.0 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) I-set PF07679.14 001257222.1_08023001_1 - 0.037 14.0 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin I-set domain P12 PF12669.5 001257222.1_08023001_1 - 0.095 13.0 3.5 0.19 12.0 3.5 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family LAX PF15681.3 001257222.1_08023001_1 - 0.17 10.4 2.2 0.3 9.6 2.2 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X Trypsin PF00089.24 001204310.1_08022001_1 - 4.9e-67 225.8 0.0 5.7e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001204310.1_08022001_1 - 2.9e-07 31.3 0.0 4.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001204310.1_08022001_1 - 2.5e-06 27.7 0.0 4.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Lectin_C PF00059.19 001257247.1_08022001_3 - 1.5e-09 38.4 0.2 3.6e-09 37.2 0.2 1.6 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.10 001257247.1_08022001_3 - 5.3e-05 22.8 0.2 6.3e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001257247.1_08022001_3 - 0.012 14.8 0.1 0.021 14.0 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Trypsin PF00089.24 001267748.1_08023001_1 - 3.8e-62 209.9 0.2 4.6e-62 209.6 0.2 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001267748.1_08023001_1 - 5.3e-09 37.0 0.0 8.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001267748.1_08023001_1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ribosomal_S25 PF03297.13 001253774.1_08021001_1 - 1.3e-49 166.4 8.0 1.9e-49 165.9 8.0 1.3 1 0 0 1 1 1 1 S25 ribosomal protein Mt_ATP-synt_D PF05873.10 001253774.1_08021001_1 - 0.02 14.6 0.2 0.028 14.2 0.2 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Fe_dep_repress PF01325.17 001253774.1_08021001_1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.17 001253774.1_08021001_1 - 0.11 12.2 0.2 0.24 11.2 0.1 1.6 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB AIPR PF10592.7 001253774.1_08021001_1 - 0.13 11.8 0.6 0.17 11.3 0.6 1.3 1 1 0 1 1 1 0 AIPR protein MarR_2 PF12802.5 001253774.1_08021001_1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.4 001253774.1_08021001_1 - 0.14 11.6 0.2 0.29 10.6 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TFIIA PF03153.11 001204841.1_08024001_3 - 1.1e-126 424.1 0.7 1.2e-126 423.9 0.7 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit APOBEC_N PF08210.9 001301845.1_08022001_1 - 1.3e-45 155.3 0.0 1.6e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001301845.1_08022001_1 - 4.6e-31 106.5 0.0 7.3e-31 105.8 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like C-terminal domain Lectin_C PF00059.19 001112638.1_40422001_2 - 5.1e-10 39.9 1.1 5.1e-10 39.9 1.1 2.2 3 0 0 3 3 3 1 Lectin C-type domain UL45 PF05473.10 001112638.1_40422001_2 - 7.2e-08 32.2 0.3 8.9e-08 31.9 0.3 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001112638.1_40422001_2 - 0.0053 15.9 2.4 0.0087 15.2 2.2 1.5 1 1 0 1 1 1 1 Chordopoxvirus A33R protein Ig_3 PF13927.4 001112639.1_40422001_1 - 2.4e-11 44.0 0.1 2.5e-05 24.7 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001112639.1_40422001_1 - 1.8e-09 37.4 0.4 0.00034 20.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.23 001112639.1_40422001_1 - 1.3e-08 34.8 0.0 1.1e-05 25.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.15 001112639.1_40422001_1 - 1.3e-08 34.8 0.1 3e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.4 001112639.1_40422001_1 - 3.3e-06 27.2 0.0 0.1 12.8 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.9 001112639.1_40422001_1 - 0.0034 17.2 0.1 0.0057 16.5 0.1 1.4 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.14 001112639.1_40422001_1 - 0.06 12.0 0.0 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EIF4E-T PF10477.7 001168771.1_40426001_1 - 5.3e-176 587.1 7.0 5.3e-176 587.1 7.0 1.6 2 0 0 2 2 2 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Glycolytic PF00274.17 001168771.1_40426001_1 - 0.023 13.3 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Ald_Xan_dh_C2 PF02738.16 001308438.1_40429001_1 - 4.7e-176 586.3 0.5 1.6e-135 452.6 0.1 2.1 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001308438.1_40429001_1 - 1e-45 155.4 0.0 2.7e-45 154.0 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001308438.1_40429001_1 - 8.7e-31 106.4 0.4 1.5e-30 105.7 0.4 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001308438.1_40429001_1 - 1.5e-30 104.8 0.2 3.3e-30 103.7 0.2 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001308438.1_40429001_1 - 1.3e-26 92.6 0.0 3e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001308438.1_40429001_1 - 6.7e-08 32.3 0.1 6.7e-08 32.3 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.7 001308438.1_40429001_1 - 0.014 15.1 1.2 0.04 13.6 1.2 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Tantalus PF15386.4 001168772.1_40423001_1 - 6e-25 87.0 2.4 6e-25 87.0 2.4 1.9 2 0 0 2 2 2 1 Drosophila Tantalus-like SSF PF00474.15 001168774.1_40423001_1 - 1.9e-114 382.6 14.0 2.8e-114 382.0 14.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3754 PF12576.6 001168774.1_40423001_1 - 0.73 9.7 3.4 0.44 10.4 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) LBP_BPI_CETP PF01273.23 001168776.1_40424001_1 - 8e-42 142.5 0.0 2.2e-41 141.1 0.0 1.8 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.15 001168776.1_40424001_1 - 9e-42 143.0 0.8 1.2e-41 142.6 0.8 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Defensin_propep PF00879.16 001112643.1_40421001_1 - 7e-27 93.4 3.4 9.1e-27 93.0 3.4 1.1 1 0 0 1 1 1 1 Defensin propeptide Defensin_1 PF00323.17 001112643.1_40421001_1 - 0.029 14.8 11.0 0.041 14.3 11.0 1.2 1 0 0 1 1 1 0 Mammalian defensin Defensin_propep PF00879.16 001112644.1_40421001_1 - 9.9e-27 92.9 4.8 1.3e-26 92.5 4.8 1.1 1 0 0 1 1 1 1 Defensin propeptide Defensin_1 PF00323.17 001112644.1_40421001_1 - 6.7e-11 42.4 13.3 9.5e-11 41.9 13.3 1.2 1 0 0 1 1 1 1 Mammalian defensin Lectin_C PF00059.19 001112645.1_40422001_3 - 1.4e-17 64.2 1.1 3.1e-17 63.1 1.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.10 001112645.1_40422001_3 - 6.8e-05 22.5 6.3 0.00019 21.0 6.3 1.6 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.10 001112645.1_40422001_3 - 0.00081 18.6 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Apolipoprotein PF01442.16 001112646.1_40422001_3 - 2.5e-54 184.0 10.6 6.4e-54 182.7 10.8 1.5 2 0 0 2 2 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.5 001112646.1_40422001_3 - 4.3e-06 27.0 7.5 11 6.5 7.5 4.6 1 1 0 1 1 1 0 YtxH-like protein ApoLp-III PF07464.9 001112646.1_40422001_3 - 3.5e-05 23.8 1.8 0.037 14.0 1.0 3.1 1 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.13 001112646.1_40422001_3 - 0.00012 21.7 3.7 0.00016 21.2 3.7 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF883 PF05957.11 001112646.1_40422001_3 - 0.00015 22.1 10.5 0.48 10.9 1.7 3.9 2 1 3 5 5 4 3 Bacterial protein of unknown function (DUF883) ApoC-I PF04691.10 001112646.1_40422001_3 - 0.00018 21.2 1.3 0.82 9.5 0.0 4.1 3 1 1 4 4 4 1 Apolipoprotein C-I (ApoC-1) DUF1640 PF07798.9 001112646.1_40422001_3 - 0.00032 20.7 2.2 0.0011 18.9 1.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) DUF4455 PF14643.4 001112646.1_40422001_3 - 0.0004 19.1 8.8 0.0012 17.5 8.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4455) DHC_N1 PF08385.10 001112646.1_40422001_3 - 0.00055 18.5 0.1 0.00074 18.1 0.1 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF948 PF06103.9 001112646.1_40422001_3 - 0.00075 19.6 0.2 0.11 12.6 0.1 3.2 1 1 2 4 4 3 1 Bacterial protein of unknown function (DUF948) Mating_N PF12731.5 001112646.1_40422001_3 - 0.00086 19.2 0.4 4.3 7.4 0.0 4.1 2 1 2 4 4 4 0 Mating-type protein beta 1 Gp-FAR-1 PF05823.10 001112646.1_40422001_3 - 0.0021 18.3 1.7 0.2 11.8 0.2 3.2 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TipAS PF07739.11 001112646.1_40422001_3 - 0.0044 17.4 5.9 1.3 9.5 1.9 2.9 1 1 1 2 2 2 2 TipAS antibiotic-recognition domain Baculo_PEP_C PF04513.10 001112646.1_40422001_3 - 0.0053 16.7 0.0 4.3 7.2 0.0 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoA-II PF04711.11 001112646.1_40422001_3 - 0.0078 16.2 3.2 0.15 12.1 0.1 3.8 2 2 3 5 5 5 1 Apolipoprotein A-II (ApoA-II) DUF2894 PF11445.6 001112646.1_40422001_3 - 0.0098 16.2 6.9 0.38 11.1 2.7 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF2894) RRF PF01765.17 001112646.1_40422001_3 - 0.017 15.0 1.3 4.4 7.1 0.6 2.3 1 1 1 2 2 2 0 Ribosome recycling factor BAR PF03114.16 001112646.1_40422001_3 - 0.018 14.6 3.4 0.24 10.9 1.0 2.2 1 1 0 2 2 2 0 BAR domain DUF1664 PF07889.10 001112646.1_40422001_3 - 0.019 14.8 0.7 0.21 11.4 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Gp58 PF07902.9 001112646.1_40422001_3 - 0.025 12.9 0.0 0.031 12.6 0.0 1.3 1 0 0 1 1 1 0 gp58-like protein DUF4795 PF16043.3 001112646.1_40422001_3 - 0.026 14.0 4.9 0.09 12.2 4.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) OmpH PF03938.12 001112646.1_40422001_3 - 0.027 14.3 7.0 0.031 14.1 2.8 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF445 PF04286.10 001112646.1_40422001_3 - 0.027 14.2 3.1 0.45 10.1 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF445) ApoO PF09769.7 001112646.1_40422001_3 - 0.029 14.2 0.5 15 5.4 0.1 3.2 1 1 2 3 3 3 0 Apolipoprotein O DUF4015 PF13200.4 001112646.1_40422001_3 - 0.073 12.0 0.1 0.26 10.2 0.1 1.8 2 0 0 2 2 2 0 Putative glycosyl hydrolase domain Mis14 PF08641.10 001112646.1_40422001_3 - 0.074 13.2 4.8 0.46 10.6 2.7 2.8 1 1 1 2 2 2 0 Kinetochore protein Mis14 like Phasin PF05597.9 001112646.1_40422001_3 - 0.084 12.8 4.4 0.56 10.1 1.9 3.1 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Prominin PF05478.9 001112646.1_40422001_3 - 0.088 10.6 0.2 0.42 8.4 0.1 1.7 1 1 1 2 2 2 0 Prominin Fzo_mitofusin PF04799.11 001112646.1_40422001_3 - 0.11 11.9 1.5 0.34 10.3 0.4 2.1 1 1 1 2 2 2 0 fzo-like conserved region BshC PF10079.7 001112646.1_40422001_3 - 0.12 10.9 5.7 0.21 10.1 4.0 1.8 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC MIF4G_like_2 PF09090.9 001112646.1_40422001_3 - 0.14 11.5 5.5 9 5.5 5.5 2.1 1 1 0 1 1 1 0 MIF4G like LMP PF04778.10 001112646.1_40422001_3 - 0.14 11.9 1.0 0.28 10.9 0.5 1.7 2 0 0 2 2 2 0 LMP repeated region DUF4407 PF14362.4 001112646.1_40422001_3 - 0.15 11.2 2.0 0.21 10.8 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.4 001112646.1_40422001_3 - 0.25 10.8 4.3 0.49 9.9 1.9 2.2 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus KMP11 PF03037.14 001112646.1_40422001_3 - 0.27 11.9 3.5 0.77 10.5 1.3 2.5 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 TBPIP PF07106.11 001112646.1_40422001_3 - 0.33 10.6 5.3 6.9 6.3 0.8 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RGS-like PF09128.9 001112646.1_40422001_3 - 0.4 10.2 2.9 0.48 10.0 1.9 1.6 1 1 1 2 2 2 0 Regulator of G protein signalling-like domain DUF3618 PF12277.6 001112646.1_40422001_3 - 0.48 10.6 11.4 3.2 8.0 0.0 4.6 4 1 2 6 6 4 0 Protein of unknown function (DUF3618) Muted PF14942.4 001112646.1_40422001_3 - 0.49 10.6 5.9 0.78 9.9 3.5 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein HIP1_clath_bdg PF16515.3 001112646.1_40422001_3 - 0.49 10.9 10.3 0.27 11.7 4.9 2.6 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1690 PF07956.9 001112646.1_40422001_3 - 0.54 10.6 8.8 3.5 7.9 3.4 2.8 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) MRP-S27 PF10037.7 001112646.1_40422001_3 - 0.86 8.3 7.1 0.51 9.1 3.6 2.0 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TetR_C_6 PF13977.4 001112646.1_40422001_3 - 0.86 9.7 7.8 2.5 8.3 3.6 2.7 2 1 1 3 3 2 0 Bacterial transcriptional repressor FlgN PF05130.10 001112646.1_40422001_3 - 1 9.7 11.5 0.59 10.5 2.6 2.5 1 1 1 2 2 2 0 FlgN protein Nnf1 PF03980.12 001112646.1_40422001_3 - 1.7 8.9 9.1 8.2 6.7 2.0 3.5 2 1 1 3 3 3 0 Nnf1 YlqD PF11068.6 001112646.1_40422001_3 - 1.8 8.8 6.2 1.5 9.1 3.8 1.9 1 1 1 2 2 2 0 YlqD protein DUF1451 PF07295.9 001112646.1_40422001_3 - 1.9 8.4 6.2 1.6 8.6 3.1 2.1 1 1 1 2 2 2 0 Zinc-ribbon containing domain Prp19 PF08606.9 001112646.1_40422001_3 - 2.7 7.9 9.0 3.4 7.6 0.1 4.4 2 1 2 4 4 4 0 Prp19/Pso4-like Snapin_Pallidin PF14712.4 001112646.1_40422001_3 - 5 7.5 6.1 9.4 6.6 2.1 3.1 1 1 1 3 3 3 0 Snapin/Pallidin V-set_2 PF15910.3 001112649.1_40422001_2 - 8.5e-13 48.3 0.8 1.2e-12 47.8 0.8 1.2 1 0 0 1 1 1 1 ICOS V-set domain V-set PF07686.15 001112649.1_40422001_2 - 2.4e-05 24.3 0.2 3.1e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ADH_zinc_N PF00107.24 001168787.1_40422001_1 - 9.8e-06 25.4 0.1 1.6e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.10 001168787.1_40422001_1 - 0.00032 20.4 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Globin PF00042.20 001168851.1_40421001_1 - 6.2e-31 107.1 0.1 2.3e-30 105.3 0.0 1.7 2 0 0 2 2 2 1 Globin GM_CSF PF01109.15 001112651.1_40422001_3 - 3.6e-66 220.7 0.1 4.4e-66 220.5 0.1 1.1 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor FOXP-CC PF16159.3 001168922.1_40425001_1 - 3.4e-35 120.3 4.2 3.4e-35 120.3 4.2 4.6 4 1 1 5 5 1 1 FOXP coiled-coil domain Forkhead PF00250.16 001168922.1_40425001_1 - 2.5e-28 98.1 0.2 1.1e-27 96.0 0.2 2.1 1 0 0 1 1 1 1 Forkhead domain RR_TM4-6 PF06459.10 001168922.1_40425001_1 - 0.14 11.8 23.1 0.32 10.7 23.1 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Plasmodium_Vir PF05795.9 001168922.1_40425001_1 - 0.3 10.3 11.4 0.69 9.1 9.4 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF4746 PF15928.3 001168922.1_40425001_1 - 0.39 10.0 13.0 0.76 9.0 13.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) VID27 PF08553.8 001168922.1_40425001_1 - 0.76 8.1 22.8 1.1 7.6 22.8 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Tim54 PF11711.6 001168922.1_40425001_1 - 0.92 8.1 16.7 1.9 7.1 16.7 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.9 001168922.1_40425001_1 - 2.3 7.5 22.8 4.3 6.6 22.8 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SID-1_RNA_chan PF13965.4 001168922.1_40425001_1 - 4.4 5.5 10.9 6.5 5.0 10.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Glyco_transf_41 PF13844.4 001168922.1_40425001_1 - 4.6 5.5 18.6 2.6 6.3 14.4 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 41 eIF-3_zeta PF05091.10 001168922.1_40425001_1 - 4.9 5.9 32.4 7.9 5.2 32.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4776 PF16003.3 001168922.1_40425001_1 - 5.4 5.7 27.8 10 4.8 27.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Apt1 PF10351.7 001168922.1_40425001_2 - 0.14 10.9 19.0 0.18 10.5 19.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1510 PF07423.9 001168922.1_40425001_2 - 2.7 7.3 8.2 3.8 6.7 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HMG14_17 PF01101.16 001168994.1_40421001_1 - 8.9e-34 116.2 27.5 1e-33 116.0 27.5 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 UDPGT PF00201.16 001112659.1_40424001_3 - 2.2e-240 798.5 0.2 2.5e-240 798.3 0.2 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001112659.1_40424001_3 - 1.2e-08 34.9 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Serpin PF00079.18 001169069.1_40423001_1 - 1.1e-119 399.9 0.0 1.3e-119 399.7 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) ANF_receptor PF01094.26 001168924.1_40426001_1 - 4.4e-105 351.5 0.0 5.7e-105 351.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.20 001168924.1_40426001_1 - 1.6e-59 201.5 16.6 2.4e-59 200.8 16.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.12 001168924.1_40426001_1 - 2.3e-14 53.0 11.6 4.7e-14 52.0 11.6 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001168924.1_40426001_1 - 5.5e-07 29.5 0.0 1.5e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein CHD5 PF04420.12 001168995.1_40421001_1 - 2.7e-33 115.0 1.3 2.9e-33 114.8 1.3 1.0 1 0 0 1 1 1 1 CHD5-like protein DUF2203 PF09969.7 001168995.1_40421001_1 - 0.00094 19.8 1.5 0.087 13.4 0.6 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2203) DUF1043 PF06295.10 001168995.1_40421001_1 - 0.0031 17.4 1.9 0.0037 17.1 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) DUF4781 PF16013.3 001168995.1_40421001_1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4781) DUF1640 PF07798.9 001168995.1_40421001_1 - 0.14 12.1 5.7 0.26 11.2 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Lectin_N PF03954.12 001168995.1_40421001_1 - 0.15 11.7 0.6 0.22 11.1 0.6 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MCU PF04678.11 001168995.1_40421001_1 - 0.65 10.0 7.3 3.6 7.6 7.3 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Asp PF00026.21 001168747.1_40423001_1 - 2.3e-118 395.1 4.5 2.7e-118 394.9 4.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001168747.1_40423001_1 - 8.9e-20 71.6 7.4 1.7e-10 41.3 0.3 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001168747.1_40423001_1 - 1.3e-13 50.4 0.9 2e-13 49.7 0.9 1.3 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.4 001168747.1_40423001_1 - 0.00015 21.5 0.0 0.00083 19.0 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.4 001168747.1_40423001_1 - 0.0032 18.0 0.0 4.7 7.8 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.4 001168747.1_40423001_1 - 0.073 13.5 0.0 20 5.7 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease LEM PF03020.13 001168800.1_40422001_1 - 1.4e-13 50.0 0.0 2.3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 LEM domain DUF912 PF06024.10 001168800.1_40422001_1 - 0.038 14.1 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UDPGT PF00201.16 001112621.1_40424001_1 - 1.7e-248 825.3 0.0 2e-248 825.1 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001112621.1_40424001_1 - 1.5e-08 34.7 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.16 001112623.1_40424001_1 - 9.4e-243 806.3 0.1 1.1e-242 806.1 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001112623.1_40424001_1 - 1.5e-08 34.6 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Med20 PF08612.9 001168751.1_40422001_1 - 6.6e-47 159.6 0.0 7.5e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Cyclin_N PF00134.21 001168753.1_40422001_1 - 3.6e-36 123.6 0.8 4.9e-36 123.2 0.8 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001168753.1_40422001_1 - 3.3e-18 65.8 0.0 1.9e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.8 001168753.1_40422001_1 - 0.035 14.4 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 K cyclin, C terminal MFS_1 PF07690.14 001168942.1_40423001_1 - 6.7e-61 206.0 32.8 1.2e-59 201.9 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cas1_AcylT PF07779.10 001168942.1_40423001_1 - 0.0026 16.6 1.9 0.0052 15.6 1.9 1.4 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Methyltransf_3 PF01596.15 001136142.2_40424001_1 - 5.1e-14 51.8 0.0 7.1e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.4 001136142.2_40424001_1 - 1.2e-09 39.0 0.0 2.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 001136142.2_40424001_1 - 0.0039 16.8 0.0 0.0058 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.4 001136142.2_40424001_1 - 0.034 13.8 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LRR_9 PF14580.4 001136142.2_40424001_2 - 0.0004 19.8 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.4 001136142.2_40424001_2 - 0.002 17.7 0.6 0.0034 17.0 0.6 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.5 001136142.2_40424001_2 - 0.042 14.1 0.2 0.08 13.2 0.2 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Sema PF01403.17 001168943.1_40426001_1 - 5.2e-116 387.8 0.0 7.3e-116 387.3 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.23 001168943.1_40426001_1 - 0.00013 22.3 7.3 0.00033 21.0 7.3 1.7 1 0 0 1 1 1 1 Plexin repeat MHC_I PF00129.16 001112631.1_40423001_1 - 8.3e-86 286.0 0.3 1.2e-85 285.4 0.3 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001112631.1_40423001_1 - 9.2e-17 61.2 0.0 1.7e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.10 001112631.1_40423001_1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain MHC_I_3 PF16497.3 001112631.1_40423001_1 - 0.00072 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 MHC-I family domain ig PF00047.23 001112631.1_40423001_1 - 0.00086 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain DUF357 PF04010.11 001112631.1_40423001_1 - 0.12 12.3 0.3 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF357) FA_desaturase PF00487.22 001145087.1_40423001_1 - 1.9e-33 116.3 29.3 1.9e-33 116.3 29.3 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.26 001145087.1_40423001_1 - 5.5e-21 74.4 0.0 1.1e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SCNM1_acidic PF15805.3 001168946.1_40422001_1 - 7.9e-26 89.4 0.6 1.7e-25 88.3 0.6 1.5 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 zf-SCNM1 PF15803.3 001168946.1_40422001_1 - 1.6e-15 56.3 1.5 2.8e-15 55.5 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of sodium channel modifier 1 CoA_transf_3 PF02515.15 001112633.1_40423001_1 - 2.3e-82 276.9 0.0 4.3e-82 276.0 0.0 1.4 1 1 0 1 1 1 1 CoA-transferase family III Tropomodulin PF03250.12 001168947.1_40423001_1 - 6e-58 194.7 6.6 6e-58 194.7 6.6 1.6 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.4 001168947.1_40423001_1 - 0.12 12.4 2.3 0.3 11.1 0.1 2.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.5 001168947.1_40423001_1 - 0.13 12.5 1.1 22 5.5 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) TBPIP PF07106.11 001168947.1_40423001_1 - 0.32 10.6 2.9 0.39 10.3 0.2 2.3 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V-set PF07686.15 001112634.1_40422001_2 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set_2 PF15910.3 001112634.1_40422001_2 - 6.7e-05 22.8 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 ICOS V-set domain Ig_3 PF13927.4 001112634.1_40422001_2 - 0.031 14.8 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.14 001112634.1_40422001_2 - 0.13 12.2 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain PIP5K PF01504.16 001168949.1_40424001_1 - 2.2e-92 309.0 0.0 3.3e-92 308.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase TMC PF07810.11 001168876.1_40425001_1 - 1.1e-42 144.9 1.1 5e-42 142.8 1.1 2.2 1 0 0 1 1 1 1 TMC domain RSN1_7TM PF02714.13 001168876.1_40425001_1 - 8 5.6 18.8 1.3 8.2 11.6 3.0 2 1 1 3 3 3 0 Calcium-dependent channel, 7TM region, putative phosphate IPI_T4 PF11634.6 001168876.1_40425001_3 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 14-3-3 PF00244.18 001168728.1_40422001_1 - 3.8e-104 346.9 9.2 4.3e-104 346.7 9.2 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF722 PF05263.9 001168728.1_40422001_1 - 0.023 14.8 0.9 0.062 13.4 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF722) CodY PF06018.12 001168728.1_40422001_1 - 0.056 12.8 0.2 0.094 12.1 0.2 1.3 1 0 0 1 1 1 0 CodY GAF-like domain FGF PF00167.16 001169086.1_40421001_1 - 9.6e-43 145.1 0.0 1.1e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 001169086.1_40421001_1 - 3.1e-07 30.4 0.1 0.0033 17.5 0.0 1.7 1 1 1 2 2 2 2 Fascin domain UDPGT PF00201.16 001172138.2_40424001_1 - 9.4e-261 865.7 0.4 1.1e-260 865.5 0.4 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001172138.2_40424001_1 - 2.5e-07 30.7 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.4 001172138.2_40424001_1 - 0.0026 17.7 0.0 0.026 14.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Nfu_N PF08712.9 001172138.2_40424001_1 - 0.0041 17.0 0.1 3.1 7.8 0.0 2.8 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal UDPGT PF00201.16 001172139.1_40424001_2 - 4.3e-260 863.5 1.3 5e-260 863.3 1.3 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001172139.1_40424001_2 - 2.4e-07 30.7 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.4 001172139.1_40424001_2 - 0.00012 21.9 0.0 0.00075 19.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Nfu_N PF08712.9 001172139.1_40424001_2 - 0.0039 17.1 0.1 3.1 7.8 0.0 2.8 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal Glyco_trans_4_4 PF13579.4 001172139.1_40424001_2 - 0.014 15.7 0.0 0.055 13.8 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain UDPGT PF00201.16 001172141.1_40424001_3 - 2.2e-256 851.3 0.2 2.6e-256 851.0 0.2 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001172141.1_40424001_3 - 5.3e-07 29.6 0.0 9.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.4 001172141.1_40424001_3 - 0.00065 19.6 0.0 0.0055 16.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.4 001172141.1_40424001_3 - 0.0044 17.4 0.0 0.021 15.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.4 001172141.1_40424001_3 - 0.012 15.5 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like Proteasome PF00227.24 001168954.1_40422001_1 - 9.4e-33 113.2 0.0 1.1e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Integrin_b_cyt PF08725.9 001168954.1_40422001_1 - 0.043 13.4 0.0 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Ubiq_cyt_C_chap PF03981.10 001169092.1_40422001_1 - 1.1e-40 138.9 0.0 1.4e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone UDPGT PF00201.16 001172144.1_40424001_2 - 1.5e-258 858.5 0.4 1.7e-258 858.2 0.4 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.14 001172144.1_40424001_2 - 2.1e-07 31.0 0.0 3.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.4 001172144.1_40424001_2 - 0.0046 16.8 0.0 0.033 14.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Nfu_N PF08712.9 001172144.1_40424001_2 - 0.0094 15.8 0.1 5.5 7.0 0.0 2.7 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal Glyco_trans_4_4 PF13579.4 001172144.1_40424001_2 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Hormone_1 PF00103.18 001173130.2_40422001_1 - 3.5e-53 180.4 0.7 4.2e-53 180.2 0.7 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Trypsin PF00089.24 001112745.1_40422001_1 - 2e-66 223.8 0.0 2.3e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001112745.1_40422001_1 - 9.7e-08 32.9 0.0 1.5e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001112745.1_40422001_1 - 0.0028 17.9 0.1 0.0078 16.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) TILa PF12714.5 001112745.1_40422001_2 - 0.03 14.1 6.5 0.08 12.8 6.5 1.6 1 0 0 1 1 1 0 TILa domain IL8 PF00048.18 001173538.1_40421001_1 - 5.6e-23 80.7 2.9 6.9e-23 80.4 2.9 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF4725 PF15854.3 001173538.1_40421001_1 - 0.0078 16.3 0.2 0.0096 16.0 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4725) Trypsin PF00089.24 001173544.1_40422001_1 - 5.7e-56 189.7 0.1 6.5e-56 189.5 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.4 001173544.1_40422001_1 - 0.00027 21.7 0.1 0.00041 21.1 0.1 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.9 001173544.1_40422001_1 - 0.00034 20.8 0.0 0.00054 20.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CaiF_GrlA PF07180.9 001173544.1_40422001_1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator Ig_3 PF13927.4 001169045.1_40428001_1 - 2e-73 242.9 0.2 5.5e-13 49.2 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.14 001169045.1_40428001_1 - 2.3e-68 226.1 0.0 1.9e-12 46.9 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.19 001169045.1_40428001_1 - 6.8e-65 215.3 13.0 1.4e-16 60.5 0.0 5.9 6 0 0 6 6 6 5 Fibronectin type III domain Ig_2 PF13895.4 001169045.1_40428001_1 - 2.5e-46 155.8 0.1 1.9e-07 31.2 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.23 001169045.1_40428001_1 - 7.5e-43 144.5 0.1 9e-07 28.8 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin domain Bravo_FIGEY PF13882.4 001169045.1_40428001_1 - 5e-27 95.0 6.2 1.1e-26 93.8 6.2 1.7 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.15 001169045.1_40428001_1 - 1.7e-18 66.6 9.8 0.0023 17.9 0.0 10.5 7 4 2 10 10 10 3 Immunoglobulin V-set domain C2-set_2 PF08205.10 001169045.1_40428001_1 - 1.4e-12 47.3 0.2 0.14 12.1 0.0 5.8 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001169045.1_40428001_1 - 5.9e-08 32.9 0.0 0.11 12.8 0.0 5.6 6 0 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001169045.1_40428001_1 - 1e-07 32.3 3.1 3.2 8.2 0.0 5.8 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.3 001169045.1_40428001_1 - 0.00014 21.7 0.1 0.3 11.0 0.0 4.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain BiPBP_C PF06832.10 001169045.1_40428001_1 - 0.00019 21.2 0.2 1.3 9.0 0.0 4.5 5 0 0 5 5 4 1 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.3 001169045.1_40428001_1 - 0.054 13.7 0.1 7.3 6.9 0.0 4.2 4 1 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Interfer-bind PF09294.8 001169045.1_40428001_1 - 0.087 13.0 0.0 2 8.7 0.0 3.1 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III EVC2_like PF12297.6 001169045.1_40428001_1 - 0.29 9.6 0.0 0.43 9.1 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Pkinase PF00069.23 001173979.1_40423001_1 - 6.2e-78 261.7 0.0 7.8e-78 261.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001173979.1_40423001_1 - 3.5e-37 128.0 0.0 5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.27 001173979.1_40423001_1 - 1e-17 64.4 0.0 2.1e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.4 001173979.1_40423001_1 - 4.1e-10 39.3 0.0 2.4e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.22 001173979.1_40423001_1 - 1.2e-08 35.4 0.8 3.1e-08 34.1 0.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.4 001173979.1_40423001_1 - 0.14 12.4 0.7 1.2 9.4 0.7 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Exo_endo_phos PF03372.21 001169046.1_40422001_1 - 3.5e-08 33.6 0.0 4.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.4 001169046.1_40422001_1 - 0.041 13.6 0.0 0.17 11.6 0.0 2.0 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase Occludin_ELL PF07303.11 001168967.1_40423001_1 - 5e-30 104.1 6.1 8.2e-30 103.4 6.1 1.4 1 0 0 1 1 1 1 Occludin homology domain ELL PF10390.7 001168967.1_40423001_1 - 7.2e-12 45.3 0.0 2.4e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL BicD PF09730.7 001168967.1_40423001_1 - 0.034 12.5 0.9 0.051 11.9 0.9 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D IL5 PF02025.13 001168758.1_40421001_1 - 1e-61 206.0 0.3 1.1e-61 205.9 0.3 1.0 1 0 0 1 1 1 1 Interleukin 5 RNase_H PF00075.22 001285502.1_40424001_1 - 2.8e-43 147.4 0.0 4.4e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001285502.1_40424001_1 - 6.3e-19 67.9 0.9 1.2e-18 67.0 0.9 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001285502.1_40424001_1 - 0.005 16.4 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase-like C2 PF00168.28 001169010.1_40422001_1 - 6.2e-19 68.1 0.0 9.9e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain AAA_18 PF13238.4 001285789.1_40422001_2 - 7.1e-31 107.3 0.3 1.2e-30 106.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.4 001285789.1_40422001_2 - 2.3e-09 37.6 0.0 5.1e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.27 001285789.1_40422001_2 - 7.7e-05 23.0 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.20 001285789.1_40422001_2 - 0.00019 21.5 0.9 0.014 15.4 0.0 2.4 2 1 1 3 3 3 1 Shikimate kinase AAA_28 PF13521.4 001285789.1_40422001_2 - 0.00027 21.1 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001285789.1_40422001_2 - 0.0009 19.3 0.1 0.024 14.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain ADK PF00406.20 001285789.1_40422001_2 - 0.0014 18.6 0.0 0.0052 16.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_16 PF13191.4 001285789.1_40422001_2 - 0.0021 18.3 0.4 0.0041 17.4 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.4 001285789.1_40422001_2 - 0.0027 17.8 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain dNK PF01712.17 001285789.1_40422001_2 - 0.0048 16.6 2.0 0.67 9.6 0.3 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase NTPase_1 PF03266.13 001285789.1_40422001_2 - 0.0062 16.3 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.12 001285789.1_40422001_2 - 0.0065 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.20 001285789.1_40422001_2 - 0.015 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.16 001285789.1_40422001_2 - 0.022 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase KTI12 PF08433.8 001285789.1_40422001_2 - 0.035 13.4 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RuvB_N PF05496.10 001285789.1_40422001_2 - 0.049 12.8 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.4 001285789.1_40422001_2 - 0.05 13.5 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.4 001285789.1_40422001_2 - 0.062 12.9 1.2 0.11 12.1 0.3 1.8 2 1 1 3 3 3 0 AAA domain TsaE PF02367.15 001285789.1_40422001_2 - 0.07 13.0 0.4 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.11 001285789.1_40422001_2 - 0.096 11.9 1.5 0.23 10.7 0.2 1.9 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.9 001285789.1_40422001_2 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hormone_recep PF00104.28 001168986.1_40423001_1 - 1.4e-35 122.7 0.0 1.8e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001168986.1_40423001_1 - 5.2e-29 100.4 14.1 1.7e-28 98.8 13.8 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Sad1_UNC PF07738.11 001169011.1_40423001_1 - 4.2e-40 136.7 0.0 6.9e-40 136.0 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal IncA PF04156.12 001169011.1_40423001_1 - 0.004 16.8 3.6 0.0068 16.1 3.6 1.4 1 1 0 1 1 1 1 IncA protein SlyX PF04102.10 001169011.1_40423001_1 - 0.21 12.1 1.7 0.42 11.1 1.7 1.4 1 0 0 1 1 1 0 SlyX PspB PF06667.10 001169011.1_40423001_1 - 0.26 11.2 0.7 0.54 10.2 0.7 1.5 1 1 0 1 1 1 0 Phage shock protein B PX PF00787.22 001168987.1_40421001_1 - 2.2e-28 98.4 0.0 2.7e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 PX domain TBPIP PF07106.11 045671.1_26223120_1 - 3.5e-19 69.1 5.7 4.6e-19 68.7 5.7 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF812 PF05667.9 045671.1_26223120_1 - 0.0065 15.3 0.3 0.0084 14.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) NPA PF16469.3 045671.1_26223120_1 - 0.013 16.1 4.6 0.02 15.4 4.6 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Ax_dynein_light PF10211.7 045671.1_26223120_1 - 0.1 12.4 5.8 0.14 11.9 5.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Spc24 PF08286.9 045671.1_26223120_1 - 0.15 12.2 0.7 0.25 11.5 0.7 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF342 PF03961.11 045671.1_26223120_1 - 0.22 10.0 3.1 0.29 9.6 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cnn_1N PF07989.9 045671.1_26223120_1 - 0.36 10.8 2.4 0.59 10.2 2.4 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 CCDC-167 PF15188.4 045671.1_26223120_1 - 1.2 9.4 3.4 2 8.7 3.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TBPIP PF07106.11 045671.1_26223120_2 - 2.6e-28 98.8 0.4 4.1e-28 98.1 0.4 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Penicillinase_R PF03965.14 045671.1_26223120_2 - 0.0021 18.2 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor Cupin_8 PF13621.4 001204228.1_08023001_3 - 1.1e-76 257.9 0.0 1.3e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.20 001204228.1_08023001_3 - 0.016 15.6 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase RhoGAP PF00620.25 001204391.1_08023001_1 - 3.2e-41 140.6 0.0 7.3e-41 139.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.4 001204391.1_08023001_1 - 6.2e-39 133.1 1.6 1.2e-38 132.2 1.6 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.18 001204391.1_08023001_1 - 2.2e-12 46.8 0.1 4.4e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain 7tm_1 PF00001.19 001204433.1_08024001_1 - 2.7e-27 95.5 0.5 5.3e-27 94.6 0.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001204433.1_08024001_1 - 0.15 11.3 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Adap_comp_sub PF00928.19 001204840.1_08029001_3 - 3.5e-59 200.2 0.5 4.8e-59 199.7 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family zf-H2C2_2 PF13465.4 001270937.1_08028001_1 - 1e-146 471.3 144.6 1.2e-09 38.1 0.4 23.0 23 0 0 23 23 23 21 Zinc-finger double domain zf-C2H2 PF00096.24 001270937.1_08028001_1 - 2.2e-109 352.1 162.4 3.8e-06 26.9 2.3 23.0 22 0 0 22 22 22 21 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270937.1_08028001_1 - 7.3e-57 184.9 155.1 0.0036 17.9 0.3 22.1 22 0 0 22 22 21 20 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001270937.1_08028001_1 - 1.1e-30 104.8 133.2 0.00081 19.1 1.1 21.4 21 1 0 21 21 21 15 C2H2-type zinc finger KRAB PF01352.25 001270937.1_08028001_1 - 4.4e-25 87.0 0.3 1e-24 85.8 0.1 1.8 2 0 0 2 2 1 1 KRAB box Zn-ribbon_8 PF09723.8 001270937.1_08028001_1 - 6.4e-20 70.9 95.5 0.0045 16.9 3.0 14.3 7 4 11 18 18 18 14 Zinc ribbon domain zf-C2H2_11 PF16622.3 001270937.1_08028001_1 - 7.9e-12 44.6 102.2 0.0021 17.6 0.1 19.3 21 0 0 21 21 21 6 zinc-finger C2H2-type C1_1 PF00130.20 001270937.1_08028001_1 - 3e-10 39.7 86.0 0.07 12.9 1.3 15.6 2 2 14 16 16 16 10 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.6 001270937.1_08028001_1 - 2.4e-05 24.4 87.0 0.12 12.6 0.0 17.7 21 0 0 21 21 20 4 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.3 001270937.1_08028001_1 - 0.0001 22.8 82.2 0.25 12.0 1.2 11.0 3 2 7 11 11 11 5 zinc-ribbon family FAM178 PF14816.4 001270937.1_08028001_1 - 0.0053 15.6 3.9 27 3.5 0.1 6.6 2 2 5 8 8 8 0 Family of unknown function, FAM178 GAGA PF09237.9 001270937.1_08028001_1 - 0.0094 15.6 20.6 0.77 9.5 0.0 7.5 8 1 1 9 9 9 1 GAGA factor MRP-S23 PF10484.7 001270937.1_08028001_1 - 0.027 14.6 0.0 1.3e+02 2.7 0.0 5.4 6 1 0 6 6 5 0 Mitochondrial ribosomal protein S23 HNH PF01844.21 001270937.1_08028001_1 - 0.036 14.1 0.4 0.036 14.1 0.4 14.1 20 0 0 20 20 20 0 HNH endonuclease DUF3656 PF12392.6 001270937.1_08028001_1 - 0.037 14.5 0.0 22 5.6 0.0 4.9 4 1 0 5 5 3 0 Collagenase ADK_lid PF05191.12 001270937.1_08028001_1 - 0.11 12.4 90.3 0.26 11.2 2.0 13.6 7 3 2 10 10 9 0 Adenylate kinase, active site lid ZZ PF00569.15 001270937.1_08028001_1 - 0.28 10.9 91.2 3.1 7.6 0.3 18.9 20 0 0 20 20 20 0 Zinc finger, ZZ type XPA_N PF01286.16 001270937.1_08028001_1 - 0.44 10.5 85.6 3.4 7.6 0.0 19.8 22 0 0 22 22 22 0 XPA protein N-terminal Barwin PF00967.15 001270937.1_08028001_1 - 4.2 7.1 9.1 4.5 7.0 0.1 4.6 4 1 0 4 4 4 0 Barwin family zf-H2C2_2 PF13465.4 001270904.1_08029001_2 - 1.4e-87 284.3 92.2 1.1e-08 35.0 1.9 15.9 15 0 0 15 15 15 13 Zinc-finger double domain zf-C2H2 PF00096.24 001270904.1_08029001_2 - 8.2e-52 170.8 102.6 4.3e-06 26.8 1.6 14.4 13 0 0 13 13 13 13 Zinc finger, C2H2 type KRAB PF01352.25 001270904.1_08029001_2 - 1.8e-22 78.6 0.5 3.4e-22 77.7 0.5 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001270904.1_08029001_2 - 1e-19 69.3 104.4 0.0091 16.6 0.5 15.3 14 0 0 14 14 14 11 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001270904.1_08029001_2 - 1.3e-11 44.0 78.2 0.13 12.1 0.2 13.8 13 0 0 13 13 13 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001270904.1_08029001_2 - 1.9e-08 34.3 52.4 0.37 11.0 0.1 12.7 13 0 0 13 13 13 7 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001270904.1_08029001_2 - 4.3e-06 26.6 66.3 0.24 11.4 2.6 9.6 5 3 3 9 9 9 8 Zinc ribbon domain XPA_N PF01286.16 001270904.1_08029001_2 - 0.014 15.3 59.1 7 6.7 0.1 13.2 13 0 0 13 13 13 0 XPA protein N-terminal KH_1 PF00013.27 001270721.1_08023001_3 - 0.00074 19.2 0.7 0.0017 18.0 0.7 1.6 1 0 0 1 1 1 1 KH domain RRP7 PF12923.5 001270721.1_08023001_3 - 0.088 12.9 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) zf-H2C2_2 PF13465.4 001270918.1_08029001_2 - 2.5e-35 119.2 58.8 5.3e-07 29.7 0.7 9.7 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.24 001270918.1_08029001_2 - 3.2e-28 96.5 66.0 4.9e-05 23.4 1.4 9.3 9 0 0 9 9 9 6 Zinc finger, C2H2 type KRAB PF01352.25 001270918.1_08029001_2 - 7.8e-23 79.7 0.1 1.6e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001270918.1_08029001_2 - 4.7e-12 45.5 58.9 0.0041 17.7 4.3 8.8 8 0 0 8 8 8 6 C2H2-type zinc finger FYVE PF01363.19 001270918.1_08029001_2 - 0.4 10.7 26.8 21 5.2 9.3 4.0 1 1 1 2 2 2 0 FYVE zinc finger DUF3268 PF11672.6 001270918.1_08029001_2 - 9.1 6.5 17.8 0.87 9.8 0.4 3.4 2 1 0 3 3 3 0 zinc-finger-containing domain DDE_1 PF03184.17 001270903.1_08025001_2 - 9.8e-35 119.6 0.1 1.5e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.14 001270903.1_08025001_2 - 1.6e-19 69.5 0.0 2.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.11 001270903.1_08025001_2 - 1.8e-10 40.2 2.7 1.9e-10 40.1 1.3 1.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain CENP-B_dimeris PF09026.8 001270903.1_08025001_2 - 2.9e-05 24.3 0.1 5.2e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain HTH_23 PF13384.4 001270903.1_08025001_2 - 0.0079 15.8 0.0 0.068 12.9 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.18 001270903.1_08025001_2 - 0.018 15.2 0.0 0.053 13.7 0.0 1.8 1 0 0 1 1 1 0 Transposase UPF0122 PF04297.12 001270903.1_08025001_2 - 0.076 13.1 0.2 0.23 11.6 0.2 1.8 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like zf-H2C2_2 PF13465.4 001270914.1_08027001_3 - 5.3e-116 374.2 147.7 3.3e-09 36.6 1.0 16.7 16 0 0 16 16 16 16 Zinc-finger double domain zf-C2H2 PF00096.24 001270914.1_08027001_3 - 1.4e-65 214.1 133.9 9.2e-06 25.7 1.1 16.3 16 0 0 16 16 16 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270914.1_08027001_3 - 2.9e-52 170.6 125.1 0.00049 20.6 4.8 16.3 16 0 0 16 16 15 15 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001270914.1_08027001_3 - 2.7e-32 110.0 105.9 0.00018 21.2 0.2 16.0 15 0 0 15 15 15 13 C2H2-type zinc finger KRAB PF01352.25 001270914.1_08027001_3 - 2.2e-22 78.3 2.2 3.9e-22 77.5 2.2 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_11 PF16622.3 001270914.1_08027001_3 - 2.8e-18 65.2 90.8 0.007 16.0 2.3 15.4 15 0 0 15 15 15 10 zinc-finger C2H2-type zf-C2H2_jaz PF12171.6 001270914.1_08027001_3 - 3.6e-17 62.0 70.3 0.065 13.4 0.1 14.8 13 1 1 14 14 14 10 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001270914.1_08027001_3 - 2.6e-13 49.7 86.7 0.01 15.8 2.4 11.8 3 2 12 15 15 15 12 Zinc ribbon domain zf-trcl PF13451.4 001270914.1_08027001_3 - 2.1e-07 30.5 70.4 2.4 8.0 0.1 14.3 12 3 3 15 15 15 7 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.3 001270914.1_08027001_3 - 0.00013 22.5 68.8 0.19 12.4 1.8 8.3 1 1 7 9 9 9 6 zinc-ribbon family AAA_14 PF13173.4 001270914.1_08027001_3 - 0.16 11.9 0.8 69 3.4 0.0 3.9 4 0 0 4 4 4 0 AAA domain XPA_N PF01286.16 001270914.1_08027001_3 - 6.3 6.8 74.1 6.8 6.7 0.3 15.2 15 0 0 15 15 15 0 XPA protein N-terminal zf-H2C2_2 PF13465.4 001270919.1_08029001_1 - 9.5e-148 474.6 121.6 6.5e-10 38.9 0.7 20.2 21 0 0 21 21 20 18 Zinc-finger double domain zf-C2H2 PF00096.24 001270919.1_08029001_1 - 1.5e-105 340.0 119.5 6.2e-07 29.4 0.2 19.5 19 0 0 19 19 19 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270919.1_08029001_1 - 1.7e-54 177.6 120.4 0.0018 18.8 0.3 19.6 19 0 0 19 19 18 18 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001270919.1_08029001_1 - 5.2e-40 134.6 97.8 0.00041 20.1 0.0 19.1 19 0 0 19 19 19 16 C2H2-type zinc finger KRAB PF01352.25 001270919.1_08029001_1 - 5.8e-25 86.6 0.1 1.1e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001270919.1_08029001_1 - 1.4e-18 66.6 86.3 0.0031 17.5 1.7 12.7 7 4 9 16 16 16 13 Zinc ribbon domain zinc_ribbon_15 PF17032.3 001270919.1_08029001_1 - 5.4e-12 46.2 72.3 0.025 15.2 2.3 9.7 1 1 7 8 8 8 8 zinc-ribbon family DZR PF12773.5 001270919.1_08029001_1 - 7.4e-12 45.0 70.2 0.23 11.4 0.5 9.7 4 1 4 8 8 8 7 Double zinc ribbon zf-C2H2_jaz PF12171.6 001270919.1_08029001_1 - 3.1e-08 33.6 87.8 0.68 10.2 0.1 17.2 18 0 0 18 18 18 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001270919.1_08029001_1 - 1.9e-06 27.3 75.2 0.61 9.8 0.3 16.4 16 0 0 16 16 16 6 zinc-finger C2H2-type XPA_N PF01286.16 001270919.1_08029001_1 - 3.2e-05 23.7 86.1 4.5 7.3 0.2 18.2 18 0 0 18 18 18 1 XPA protein N-terminal zf-C2HE PF16278.3 001270919.1_08029001_1 - 0.00057 20.2 100.7 0.027 14.8 0.5 17.3 2 1 17 19 19 19 5 C2HE / C2H2 / C2HC zinc-binding finger IGPD PF00475.16 001270919.1_08029001_1 - 0.023 14.9 0.7 11 6.2 0.0 4.2 2 1 1 4 4 4 0 Imidazoleglycerol-phosphate dehydratase DUF3268 PF11672.6 001270919.1_08029001_1 - 1.3 9.3 58.7 3.3 7.9 0.8 9.2 3 2 4 11 11 11 0 zinc-finger-containing domain 2OG-FeII_Oxy_3 PF13640.4 001270908.1_08025001_1 - 7.5e-09 36.2 0.0 1.8e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.18 001270908.1_08025001_1 - 1.9e-05 24.9 0.0 4.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAM176 PF14851.4 001270908.1_08025001_1 - 2 8.0 6.7 0.56 9.7 2.8 1.9 2 0 0 2 2 2 0 FAM176 family CENP-B_N PF04218.11 001270908.1_08025001_3 - 0.13 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain zf-H2C2_2 PF13465.4 001270917.1_08026001_3 - 3.4e-125 403.3 118.4 3e-09 36.8 2.4 17.4 18 0 0 18 18 18 16 Zinc-finger double domain zf-C2H2 PF00096.24 001270917.1_08026001_3 - 1.8e-76 248.4 108.2 1.4e-06 28.3 0.3 16.8 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270917.1_08026001_3 - 3.2e-42 139.4 107.6 0.013 16.2 0.2 16.9 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001270917.1_08026001_3 - 2.5e-27 94.1 98.8 0.0011 18.7 0.8 16.6 16 0 0 16 16 16 12 C2H2-type zinc finger KRAB PF01352.25 001270917.1_08026001_3 - 4.1e-27 93.5 0.2 8e-27 92.5 0.2 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 001270917.1_08026001_3 - 1.5e-20 72.8 66.9 0.025 14.8 0.1 15.3 16 0 0 16 16 15 10 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001270917.1_08026001_3 - 1.5e-14 53.7 92.3 0.015 15.3 1.9 11.0 6 3 3 10 10 10 9 Zinc ribbon domain XPA_N PF01286.16 001270917.1_08026001_3 - 2.4e-08 33.7 77.4 2.9 7.9 0.1 16.2 16 0 0 16 16 16 6 XPA protein N-terminal zf-trcl PF13451.4 001270917.1_08026001_3 - 3.8e-08 32.9 76.8 0.34 10.7 5.5 15.3 14 2 2 16 16 16 6 Probable zinc-ribbon domain C1_4 PF07975.10 001270917.1_08026001_3 - 1.8e-05 24.7 84.4 0.15 12.2 7.5 11.3 3 1 10 14 14 14 7 TFIIH C1-like domain BHD_1 PF10403.7 001270917.1_08026001_3 - 0.015 15.0 6.1 45 3.9 0.0 6.7 4 3 3 7 7 7 0 Rad4 beta-hairpin domain 1 zf-LYAR PF08790.9 001270917.1_08026001_3 - 0.044 13.6 0.1 0.044 13.6 0.1 12.5 16 0 0 16 16 16 0 LYAR-type C2HC zinc finger DUF3268 PF11672.6 001270917.1_08026001_3 - 4.1 7.6 64.1 1.1 9.4 1.6 8.7 4 1 5 11 11 11 0 zinc-finger-containing domain zf-H2C2_2 PF13465.4 001270920.1_08029001_1 - 4.3e-146 469.3 132.8 5e-08 32.9 0.2 24.5 24 0 0 24 24 24 21 Zinc-finger double domain zf-C2H2 PF00096.24 001270920.1_08029001_1 - 2.1e-119 383.6 138.5 8.1e-07 29.0 0.9 24.1 23 0 0 23 23 23 21 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270920.1_08029001_1 - 3.9e-58 188.9 140.4 0.0051 17.4 0.6 23.8 24 0 0 24 24 23 20 C2H2-type zinc finger KRAB PF01352.25 001270920.1_08029001_1 - 2.5e-22 78.1 0.2 4.4e-22 77.3 0.2 1.4 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001270920.1_08029001_1 - 1e-18 67.0 97.2 0.0013 18.7 1.2 14.2 10 4 7 17 17 17 12 Zinc ribbon domain zf-C2H2_6 PF13912.4 001270920.1_08029001_1 - 2.3e-14 52.8 116.1 0.11 12.3 0.4 20.9 21 0 0 21 21 21 11 C2H2-type zinc finger DZR PF12773.5 001270920.1_08029001_1 - 1.3e-10 41.0 82.9 0.23 11.4 4.0 12.0 3 2 2 5 5 3 1 Double zinc ribbon DUF3268 PF11672.6 001270920.1_08029001_1 - 3.4e-06 27.3 70.8 0.31 11.3 0.5 11.7 7 2 4 13 13 13 9 zinc-finger-containing domain zf-C2H2_jaz PF12171.6 001270920.1_08029001_1 - 1.3e-05 25.2 92.3 0.079 13.2 0.1 19.2 21 0 0 21 21 21 7 Zinc-finger double-stranded RNA-binding C1_4 PF07975.10 001270920.1_08029001_1 - 1.8e-05 24.7 91.8 0.0036 17.4 1.7 13.7 8 3 7 16 16 15 8 TFIIH C1-like domain zinc_ribbon_15 PF17032.3 001270920.1_08029001_1 - 4.7e-05 23.9 85.8 0.68 10.6 1.2 11.5 4 2 12 16 16 15 9 zinc-ribbon family ADK_lid PF05191.12 001270920.1_08029001_1 - 0.025 14.5 0.4 0.025 14.5 0.4 12.4 9 3 4 14 14 14 0 Adenylate kinase, active site lid MBD PF01429.17 001270920.1_08029001_1 - 1.1 8.9 3.1 8.6 6.0 0.1 4.0 4 0 0 4 4 4 0 Methyl-CpG binding domain BDHCT_assoc PF16204.3 001270920.1_08029001_1 - 4.4 6.8 8.9 2.2 7.8 0.1 3.7 3 1 1 4 4 4 0 BDHCT-box associated domain on Bloom syndrome protein zf-H2C2_2 PF13465.4 001270907.1_08028001_2 - 1.7e-99 322.0 95.7 6.4e-09 35.7 3.2 14.7 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.24 001270907.1_08028001_2 - 8.6e-68 221.1 100.3 1.7e-06 28.0 2.9 13.8 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270907.1_08028001_2 - 1.8e-31 105.9 95.0 0.0071 17.0 0.2 14.1 13 0 0 13 13 13 12 C2H2-type zinc finger KRAB PF01352.25 001270907.1_08028001_2 - 8.3e-23 79.7 0.3 1.4e-22 78.9 0.3 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 001270907.1_08028001_2 - 2.7e-12 46.5 57.8 0.12 12.6 0.4 13.2 13 0 0 13 13 13 6 Zinc-finger double-stranded RNA-binding XPA_N PF01286.16 001270907.1_08028001_2 - 5.2e-11 42.3 56.8 3.4 7.7 0.1 13.7 13 0 0 13 13 13 6 XPA protein N-terminal zf-C2H2_6 PF13912.4 001270907.1_08028001_2 - 7.5e-11 41.6 85.9 0.084 12.7 0.8 14.3 13 1 0 13 13 13 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001270907.1_08028001_2 - 8.2e-09 35.3 73.8 0.021 14.8 1.9 9.7 2 2 9 12 12 12 8 Zinc ribbon domain zf-C2H2_11 PF16622.3 001270907.1_08028001_2 - 0.0012 18.4 71.2 0.41 10.3 0.5 12.8 13 0 0 13 13 13 7 zinc-finger C2H2-type zinc_ribbon_15 PF17032.3 001270907.1_08028001_2 - 0.0025 18.4 48.5 1.6 9.4 1.0 7.1 1 1 5 6 6 6 3 zinc-ribbon family BHD_1 PF10403.7 001270907.1_08028001_2 - 0.004 16.8 2.0 30 4.4 0.0 4.7 3 1 0 3 3 3 0 Rad4 beta-hairpin domain 1 zf-LYAR PF08790.9 001270907.1_08028001_2 - 0.066 13.0 59.6 2.5 7.9 0.1 12.5 13 0 0 13 13 13 0 LYAR-type C2HC zinc finger C1_4 PF07975.10 001270907.1_08028001_2 - 0.33 11.1 54.0 0.12 12.6 1.4 7.7 5 3 3 8 8 8 0 TFIIH C1-like domain Raffinose_syn PF05691.10 001270907.1_08028001_2 - 3.4 5.2 6.0 23 2.4 0.1 3.6 2 1 3 5 5 5 0 Raffinose synthase or seed imbibition protein Sip1 zf-H2C2_2 PF13465.4 001270936.1_08026001_2 - 2.1e-131 422.9 155.1 4e-08 33.2 0.4 21.6 21 0 0 21 21 21 21 Zinc-finger double domain zf-C2H2 PF00096.24 001270936.1_08026001_2 - 1.8e-104 336.6 182.2 3.8e-07 30.1 0.5 20.6 21 0 0 21 21 20 20 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270936.1_08026001_2 - 8.5e-52 169.2 170.6 0.0035 17.9 2.4 20.5 20 0 0 20 20 20 20 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001270936.1_08026001_2 - 3.3e-37 125.6 141.1 0.0013 18.5 1.6 20.8 20 0 0 20 20 20 18 C2H2-type zinc finger KRAB PF01352.25 001270936.1_08026001_2 - 7.7e-26 89.4 0.0 1.5e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001270936.1_08026001_2 - 1.2e-23 82.8 103.0 0.0025 17.8 2.0 14.5 5 4 13 18 18 18 17 Zinc ribbon domain C1_1 PF00130.20 001270936.1_08026001_2 - 8.4e-08 31.9 102.4 0.36 10.6 1.4 14.6 2 1 10 14 14 14 7 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.6 001270936.1_08026001_2 - 2.1e-07 30.9 100.9 0.29 11.4 0.1 18.3 19 0 0 19 19 19 8 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.3 001270936.1_08026001_2 - 1.7e-06 28.6 92.4 0.02 15.5 1.2 10.5 2 2 5 10 10 10 7 zinc-ribbon family XPA_N PF01286.16 001270936.1_08026001_2 - 0.00099 19.0 97.9 2.7 8.0 0.1 19.4 20 0 0 20 20 20 5 XPA protein N-terminal ADK_lid PF05191.12 001270936.1_08026001_2 - 0.009 15.9 104.1 0.11 12.4 1.1 13.0 9 1 5 14 14 14 7 Adenylate kinase, active site lid zf-C2H2_11 PF16622.3 001270936.1_08026001_2 - 0.048 13.3 122.8 0.077 12.6 0.7 18.9 20 0 0 20 20 20 0 zinc-finger C2H2-type C1_4 PF07975.10 001270936.1_08026001_2 - 0.094 12.9 99.4 0.041 14.0 5.3 13.2 3 3 11 15 15 15 0 TFIIH C1-like domain DUF3268 PF11672.6 001270936.1_08026001_2 - 0.3 11.3 82.2 1.5 9.0 2.9 10.6 5 1 4 12 12 12 0 zinc-finger-containing domain MHC_II_beta PF00969.17 001331056.1_40422001_1 - 7.4e-32 109.2 0.7 1.3e-31 108.4 0.7 1.4 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001331056.1_40422001_1 - 2.1e-27 95.3 0.2 9e-27 93.3 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001331056.1_40422001_1 - 4.8e-05 23.8 0.0 0.0002 21.8 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001331056.1_40422001_1 - 0.00061 19.8 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.13 001331056.1_40422001_1 - 0.00084 19.1 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Marek's disease glycoprotein A MHC_I PF00129.16 001331056.1_40422001_1 - 0.0011 18.5 0.1 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_2 PF13895.4 001331056.1_40422001_1 - 0.0018 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 001331056.1_40422001_1 - 0.0031 17.4 0.1 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain zf-H2C2_2 PF13465.4 001270915.1_08028001_2 - 1.9e-120 388.2 161.7 2.3e-08 34.0 1.3 21.6 21 0 0 21 21 21 20 Zinc-finger double domain zf-C2H2 PF00096.24 001270915.1_08028001_2 - 4e-80 259.9 159.9 2.2e-05 24.5 0.1 22.0 22 0 0 22 22 22 20 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270915.1_08028001_2 - 2.8e-36 120.9 163.4 0.035 14.8 0.3 21.8 22 0 0 22 22 20 19 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001270915.1_08028001_2 - 3.3e-26 90.6 141.4 0.0015 18.3 2.8 20.9 21 0 0 21 21 21 15 C2H2-type zinc finger KRAB PF01352.25 001270915.1_08028001_2 - 4e-20 71.1 1.4 9.8e-20 69.8 1.4 1.6 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001270915.1_08028001_2 - 4.8e-12 45.7 123.4 0.0035 17.3 2.3 14.3 9 5 10 19 19 18 14 Zinc ribbon domain zf-C2H2_jaz PF12171.6 001270915.1_08028001_2 - 1.4e-07 31.5 76.5 1.2 9.4 0.1 17.2 17 0 0 17 17 17 3 Zinc-finger double-stranded RNA-binding C1_4 PF07975.10 001270915.1_08028001_2 - 0.00012 22.1 90.1 0.38 10.9 0.7 13.9 7 3 6 14 14 14 6 TFIIH C1-like domain zf-C2HE PF16278.3 001270915.1_08028001_2 - 0.023 15.0 0.7 0.023 15.0 0.7 16.0 4 4 10 14 14 12 0 C2HE / C2H2 / C2HC zinc-binding finger CpXC PF14353.4 001270915.1_08028001_2 - 0.11 12.4 76.6 2.7 7.9 1.7 16.8 6 6 8 16 16 16 0 CpXC protein zf-C2H2_11 PF16622.3 001270915.1_08028001_2 - 0.15 11.7 0.0 0.15 11.7 0.0 16.9 19 0 0 19 19 19 0 zinc-finger C2H2-type DUF3268 PF11672.6 001270915.1_08028001_2 - 0.24 11.6 65.1 0.17 12.1 0.3 10.0 5 3 4 12 12 12 0 zinc-finger-containing domain XPA_N PF01286.16 001270915.1_08028001_2 - 0.87 9.6 111.8 3.9 7.5 0.2 19.2 20 0 0 20 20 20 0 XPA protein N-terminal RnaseA PF00074.18 001270923.1_08022001_3 - 2.7e-32 111.7 0.4 3.5e-32 111.3 0.4 1.1 1 0 0 1 1 1 1 Pancreatic ribonuclease zf-H2C2_2 PF13465.4 001270906.1_08028001_2 - 5.2e-78 254.1 79.5 3.7e-08 33.3 2.5 13.0 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.24 001270906.1_08028001_2 - 1.6e-45 150.9 86.0 6e-06 26.3 2.3 12.6 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270906.1_08028001_2 - 8.5e-26 88.3 80.8 0.017 15.8 2.4 12.4 11 0 0 11 11 11 10 C2H2-type zinc finger KRAB PF01352.25 001270906.1_08028001_2 - 1.1e-20 72.9 0.5 2e-20 72.0 0.5 1.5 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001270906.1_08028001_2 - 4.9e-08 32.8 47.1 0.079 13.0 1.6 8.4 4 3 5 9 9 9 5 Zinc ribbon domain zf-C2H2_6 PF13912.4 001270906.1_08028001_2 - 1.4e-06 28.0 65.3 0.48 10.3 0.8 12.5 11 1 0 11 11 11 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001270906.1_08028001_2 - 2.2e-05 24.5 43.9 0.48 10.7 0.5 11.6 12 0 0 12 12 11 2 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.9 001270906.1_08028001_2 - 0.00066 19.4 48.7 5.3 6.9 0.1 11.1 11 0 0 11 11 11 3 LYAR-type C2HC zinc finger XPA_N PF01286.16 001270906.1_08028001_2 - 0.00086 19.2 43.3 5.5 7.0 0.3 11.1 11 0 0 11 11 11 1 XPA protein N-terminal zinc_ribbon_15 PF17032.3 001270906.1_08028001_2 - 0.00099 19.7 30.1 1.6 9.4 0.4 5.7 4 1 0 5 5 5 2 zinc-ribbon family ADK_lid PF05191.12 001270906.1_08028001_2 - 0.023 14.6 0.8 0.023 14.6 0.8 6.2 5 2 0 5 5 5 0 Adenylate kinase, active site lid zf-trcl PF13451.4 001270906.1_08028001_2 - 0.028 14.1 45.0 1.3 8.8 0.2 9.8 9 2 0 9 9 9 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.3 001270906.1_08028001_2 - 0.033 13.8 60.8 0.1 12.3 0.1 10.7 11 0 0 11 11 11 0 zinc-finger C2H2-type zf-UBP PF02148.17 001270906.1_08028001_2 - 0.033 14.4 46.9 2 8.7 3.0 7.9 1 1 4 6 6 6 0 Zn-finger in ubiquitin-hydrolases and other protein BHD_1 PF10403.7 001270906.1_08028001_2 - 0.059 13.1 0.2 12 5.7 0.0 3.9 4 1 0 4 4 4 0 Rad4 beta-hairpin domain 1 zf-BED PF02892.13 001270906.1_08028001_2 - 2.8 7.9 55.2 4.3 7.3 0.4 9.3 2 2 5 7 7 7 0 BED zinc finger FYDLN_acid PF09538.8 001270906.1_08028001_2 - 6.1 7.4 25.9 68 4.1 1.9 8.8 1 1 8 9 9 9 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.5 001270906.1_08028001_2 - 8 6.4 50.6 0.077 12.9 4.3 6.7 4 2 1 6 6 6 0 Transposase zinc-ribbon domain DUF3268 PF11672.6 001270906.1_08028001_2 - 9.9 6.4 30.8 0.76 10.0 1.1 5.4 4 1 4 8 8 8 0 zinc-finger-containing domain MHC_I PF00129.16 001331062.1_40423001_1 - 1.5e-94 314.4 0.8 2.1e-94 314.0 0.8 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001331062.1_40423001_1 - 1.9e-16 60.2 0.0 3.7e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001331062.1_40423001_1 - 5.7e-15 54.8 8.9 1e-14 54.0 8.9 1.4 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 001331062.1_40423001_1 - 3.9e-06 27.2 0.5 0.024 15.1 0.0 2.8 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 001331062.1_40423001_1 - 0.0005 20.0 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001331062.1_40423001_1 - 0.015 15.3 0.1 0.059 13.4 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain DUF4448 PF14610.4 001331062.1_40423001_1 - 0.044 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) HLH PF00010.24 001270717.1_08022001_3 - 2.4e-13 49.7 5.8 3.5e-13 49.2 5.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pou PF00157.15 001270717.1_08022001_3 - 0.11 12.4 0.4 0.16 11.9 0.4 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain RnaseA PF00074.18 001270925.1_08024001_2 - 8.1e-40 136.0 6.3 1.7e-39 134.9 6.3 1.6 1 0 0 1 1 1 1 Pancreatic ribonuclease zf-H2C2_2 PF13465.4 001270916.1_08028001_3 - 1.8e-86 280.9 108.0 1.8e-08 34.3 0.4 14.5 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.24 001270916.1_08028001_3 - 1.3e-54 179.6 106.5 7.9e-05 22.8 3.6 13.8 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001270916.1_08028001_3 - 4.5e-26 89.1 100.9 0.024 15.3 0.9 14.1 13 0 0 13 13 13 13 C2H2-type zinc finger KRAB PF01352.25 001270916.1_08028001_3 - 4.4e-23 80.6 1.6 1.2e-22 79.1 1.6 1.8 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001270916.1_08028001_3 - 2.5e-18 65.5 84.5 0.022 14.6 0.9 13.6 13 0 0 13 13 13 11 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001270916.1_08028001_3 - 1e-12 47.8 77.8 0.0036 17.3 3.7 9.2 1 1 7 10 10 10 9 Zinc ribbon domain C1_4 PF07975.10 001270916.1_08028001_3 - 9.6e-06 25.6 64.1 0.2 11.8 5.7 9.7 3 2 6 10 10 10 4 TFIIH C1-like domain DUF3268 PF11672.6 001270916.1_08028001_3 - 0.057 13.6 46.4 1.3 9.2 2.7 7.2 5 1 3 8 8 8 0 zinc-finger-containing domain XPA_N PF01286.16 001270916.1_08028001_3 - 0.29 11.1 72.3 10 6.1 0.1 13.6 13 0 0 13 13 13 0 XPA protein N-terminal Mit_proteolip PF08039.9 001270916.1_08028001_3 - 4.5 7.5 7.4 13 6.1 7.4 1.7 1 0 0 1 1 1 0 Mitochondrial proteolipid zinc_ribbon_15 PF17032.3 001270916.1_08028001_3 - 5.3 7.7 58.0 5 7.8 1.0 7.3 4 1 4 8 8 8 0 zinc-ribbon family Glyco_transf_8 PF01501.18 138564.1_26224120_1 - 6.5e-08 32.3 0.0 9.2e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ras PF00071.20 001287560.1_09024001_3 - 1e-56 190.9 0.1 1.3e-56 190.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001287560.1_09024001_3 - 1.4e-35 122.0 0.0 2e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001287560.1_09024001_3 - 6.8e-16 58.1 0.2 9.4e-16 57.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001287560.1_09024001_3 - 1.4e-06 28.3 0.1 4.3e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001287560.1_09024001_3 - 0.00057 19.2 0.0 0.00079 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.14 001287560.1_09024001_3 - 0.0018 18.1 0.1 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001287560.1_09024001_3 - 0.002 17.6 0.2 0.0088 15.5 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.4 001287560.1_09024001_3 - 0.0069 16.6 0.1 0.01 16.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.8 001287560.1_09024001_3 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.4 001287560.1_09024001_3 - 0.014 14.9 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.4 001287560.1_09024001_3 - 0.032 14.4 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.4 001287560.1_09024001_3 - 0.056 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain BTG PF07742.10 001285677.2_09022001_3 - 2.7e-43 146.4 0.0 3.4e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 BTG family Lys PF00062.18 001287566.1_09021001_1 - 7.2e-56 187.6 5.5 8.2e-56 187.5 5.5 1.0 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.18 001287566.1_09021001_1 - 0.0049 16.4 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain ANP PF00212.16 001285679.1_09021001_1 - 4.2e-15 55.5 7.8 7.7e-15 54.6 7.8 1.5 1 0 0 1 1 1 1 Atrial natriuretic peptide Ras PF00071.20 001287569.1_09022001_1 - 5.1e-67 224.4 0.5 6.1e-67 224.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001287569.1_09022001_1 - 6.6e-34 116.6 0.1 1.1e-33 115.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001287569.1_09022001_1 - 1.2e-16 60.5 0.3 1.5e-16 60.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001287569.1_09022001_1 - 6.8e-06 25.5 0.1 8.5e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001287569.1_09022001_1 - 0.00033 20.0 0.1 0.0004 19.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001287569.1_09022001_1 - 0.0024 17.8 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001287569.1_09022001_1 - 0.0026 17.2 0.1 0.0048 16.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001287569.1_09022001_1 - 0.0031 17.3 0.2 1.6 8.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Septin PF00735.16 001287569.1_09022001_1 - 0.015 14.4 0.6 0.42 9.7 0.0 2.3 2 0 0 2 2 2 0 Septin DUF3963 PF13124.4 001287569.1_09022001_1 - 0.024 14.5 0.8 0.05 13.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_16 PF13191.4 001287569.1_09022001_1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain LRR_8 PF13855.4 001285555.1_09023001_3 - 7.9e-42 140.7 20.5 5.6e-16 57.9 2.8 4.4 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.5 001285555.1_09023001_3 - 3.4e-23 81.1 22.2 2e-05 24.7 2.2 5.8 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001285555.1_09023001_3 - 6.6e-12 45.4 0.8 6.7e-05 22.7 0.2 3.1 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001285555.1_09023001_3 - 3e-11 43.0 6.5 1.3e-05 24.7 3.1 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.16 001285555.1_09023001_3 - 2.9e-09 36.2 5.4 2.9e-09 36.2 5.4 2.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.31 001285555.1_09023001_3 - 8.8e-05 22.3 11.1 14 6.5 0.1 7.2 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.4 001285555.1_09023001_3 - 0.0021 17.8 17.3 0.34 11.0 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich repeat STAR_dimer PF16544.3 001285555.1_09023001_3 - 0.079 12.4 0.2 0.18 11.2 0.2 1.6 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein Thyroglobulin_1 PF00086.16 001285566.1_09022001_1 - 5.7e-19 67.4 2.6 1.6e-18 66.0 2.6 1.8 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001285566.1_09022001_1 - 4.9e-11 43.0 22.4 4.9e-11 43.0 22.4 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Heme_oxygenase PF01126.18 001285567.1_09022001_1 - 1.2e-80 270.0 3.0 1.5e-80 269.7 3.0 1.0 1 0 0 1 1 1 1 Heme oxygenase Cys_knot PF00007.20 001287576.1_09021001_1 - 1.9e-34 118.0 14.4 2.4e-34 117.7 14.4 1.1 1 0 0 1 1 1 1 Cystine-knot domain GM_CSF PF01109.15 001285570.1_09021001_1 - 1.8e-70 234.6 0.2 2.1e-70 234.4 0.2 1.0 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor FKBP_C PF00254.26 001285571.1_09023001_1 - 3.8e-15 55.8 0.0 7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.26 001285571.1_09023001_1 - 1.5e-11 43.5 1.7 6.2e-05 22.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.15 001285571.1_09023001_1 - 3.2e-11 42.3 1.8 1.1e-05 25.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001285571.1_09023001_1 - 7.8e-09 35.3 1.5 0.00062 19.7 0.1 2.4 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.4 001285571.1_09023001_1 - 3.6e-07 30.3 2.5 4.9e-05 23.7 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.4 001285571.1_09023001_1 - 6.3e-06 25.7 0.1 3.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.4 001285571.1_09023001_1 - 8.1e-06 25.8 0.2 2.2e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.4 001285571.1_09023001_1 - 9.4e-06 26.1 1.2 8.7e-05 23.0 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.4 001285571.1_09023001_1 - 0.00011 22.0 0.1 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.4 001285571.1_09023001_1 - 0.00019 21.8 0.2 0.00054 20.3 0.2 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.4 001285571.1_09023001_1 - 0.00055 19.7 0.4 0.071 13.1 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.4 001285571.1_09023001_1 - 0.00078 19.6 2.5 0.0011 19.1 0.4 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001285571.1_09023001_1 - 0.0063 16.6 0.4 0.039 14.0 0.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.4 001285571.1_09023001_1 - 0.0064 16.7 0.4 0.62 10.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.4 001285571.1_09023001_1 - 0.012 15.3 2.1 0.63 9.9 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.4 001285571.1_09023001_1 - 0.017 15.6 0.1 0.58 10.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.4 001285571.1_09023001_1 - 0.11 12.7 1.5 0.61 10.3 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat BCNT PF07572.10 001285692.1_09023001_3 - 3.5e-31 107.0 0.7 1.1e-30 105.4 0.7 1.9 1 0 0 1 1 1 1 Bucentaur or craniofacial development Glyco_hydro_38 PF01074.20 001289106.1_09028001_1 - 2.6e-109 364.9 1.5 3.9e-109 364.3 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.11 001289106.1_09028001_1 - 5.4e-86 289.3 0.0 7.4e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.9 001289106.1_09028001_1 - 1.1e-25 89.7 0.6 2.6e-25 88.4 0.6 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.13 001289106.1_09028001_1 - 0.00018 20.6 0.1 0.00038 19.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 BTG PF07742.10 001289948.1_09022001_3 - 9.1e-43 144.7 0.1 1.9e-42 143.7 0.1 1.5 1 0 0 1 1 1 1 BTG family SRI PF08236.9 001289948.1_09022001_3 - 0.41 10.7 5.5 0.16 12.0 2.6 1.7 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Exo_endo_phos PF03372.21 001285693.1_09025001_2 - 2.2e-08 34.2 0.0 4.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.4 001285693.1_09025001_2 - 1e-05 25.2 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Cathelicidins PF00666.15 001312693.1_09022001_2 - 0.0093 16.1 1.9 0.011 15.8 1.6 1.4 1 1 0 1 1 1 1 Cathelicidin Lipocalin PF00061.21 001285701.1_09022001_2 - 2e-30 105.7 2.4 2.4e-30 105.5 2.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001285701.1_09022001_2 - 1.2e-09 38.0 1.1 1.5e-09 37.7 1.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Pkinase_Tyr PF07714.15 001285592.1_09024001_1 - 1.4e-37 129.2 0.0 2.4e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001285592.1_09024001_1 - 4.8e-37 127.6 0.0 8.9e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.10 001285592.1_09024001_1 - 7e-16 57.3 0.7 1.4e-15 56.3 0.7 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.21 001285592.1_09024001_1 - 8.8e-12 45.8 13.6 8.8e-12 45.8 13.6 1.8 2 0 0 2 2 2 1 Activin types I and II receptor domain FTA2 PF13095.4 001285592.1_09024001_1 - 0.035 13.6 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.21 001285592.1_09024001_1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.25 001314147.1_09022001_1 - 4.4e-67 221.9 3.6 4.3e-25 87.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-H2C2_2 PF13465.4 001285593.1_09022001_1 - 2.8e-30 103.2 43.4 7e-08 32.5 2.0 6.9 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.24 001285593.1_09022001_1 - 1.4e-24 85.0 48.0 1.8e-05 24.8 2.2 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001285593.1_09022001_1 - 6.1e-19 66.9 46.7 0.0012 19.3 0.8 6.4 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001285593.1_09022001_1 - 7.6e-12 45.1 21.9 0.03 14.5 0.1 6.5 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001285593.1_09022001_1 - 1.1e-08 34.7 39.5 0.0017 18.1 1.6 6.3 6 0 0 6 6 6 4 C2H2-type zinc finger Ta0938 PF11494.6 001285593.1_09022001_1 - 8.6e-05 22.6 0.9 0.32 11.1 0.0 2.8 2 1 1 3 3 3 2 Ta0938 zf-met PF12874.5 001285593.1_09022001_1 - 0.00011 22.4 38.6 0.1 12.8 0.4 6.1 6 0 0 6 6 6 4 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.8 001285593.1_09022001_1 - 0.0047 16.9 19.8 1.3 9.0 4.1 5.1 4 2 1 5 5 5 2 Zinc ribbon domain FYVE PF01363.19 001285593.1_09022001_1 - 0.019 14.9 28.2 0.55 10.3 10.5 3.9 1 1 3 4 4 4 0 FYVE zinc finger zf-C2H2_8 PF15909.3 001285593.1_09022001_1 - 0.02 15.0 19.8 0.3 11.3 3.1 3.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon Prok-RING_1 PF14446.4 001285593.1_09022001_1 - 0.03 14.1 15.2 7.8 6.4 0.1 5.8 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zinc_ribbon_15 PF17032.3 001285593.1_09022001_1 - 0.054 14.1 14.2 1.2 9.8 1.3 3.4 1 1 3 4 4 4 0 zinc-ribbon family zf-BED PF02892.13 001285593.1_09022001_1 - 0.064 13.2 30.3 0.095 12.6 4.5 5.2 3 1 3 6 6 6 0 BED zinc finger GAGA PF09237.9 001285593.1_09022001_1 - 0.11 12.2 8.2 6.4 6.5 0.1 3.8 2 2 2 4 4 4 0 GAGA factor XPA_N PF01286.16 001285593.1_09022001_1 - 0.21 11.5 21.1 7.1 6.6 0.1 6.1 6 0 0 6 6 6 0 XPA protein N-terminal BolA PF01722.16 001285593.1_09022001_1 - 0.26 11.5 11.3 3.5 7.8 1.9 3.5 2 2 2 4 4 4 0 BolA-like protein HNH_5 PF14279.4 001285593.1_09022001_1 - 0.28 11.0 14.8 7.2 6.4 0.8 5.3 5 1 0 5 5 5 0 HNH endonuclease HypA PF01155.17 001285593.1_09022001_1 - 0.3 11.0 12.5 0.42 10.5 0.6 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S27e PF01667.15 001285593.1_09022001_1 - 0.44 10.2 7.3 1.7 8.3 0.0 4.3 5 0 0 5 5 5 0 Ribosomal protein S27 zf-CHCC PF10276.7 001285593.1_09022001_1 - 0.6 10.1 10.1 3.8 7.5 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger domain zf-AN1 PF01428.14 001285593.1_09022001_1 - 0.74 9.9 27.2 5.6 7.1 0.3 6.2 5 1 1 6 6 6 0 AN1-like Zinc finger Zf_RING PF16744.3 001285593.1_09022001_1 - 0.76 9.8 20.1 4.8 7.2 0.2 5.6 1 1 5 6 6 6 0 KIAA1045 RING finger FdhE PF04216.10 001285593.1_09022001_1 - 0.95 9.1 4.9 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation zf-LYAR PF08790.9 001285593.1_09022001_1 - 2.6 7.9 26.7 2.4 8.0 0.1 6.2 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger Perilipin PF03036.14 001285595.1_09024001_2 - 4.5e-170 565.8 21.9 9.4e-170 564.8 21.9 1.5 1 1 0 1 1 1 1 Perilipin family 2_5_RNA_ligase2 PF13563.4 001285595.1_09024001_2 - 0.068 13.0 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily DUF883 PF05957.11 001285595.1_09024001_2 - 0.1 13.0 15.2 3.2 8.2 0.7 4.7 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF2497 PF10691.7 001285595.1_09024001_2 - 0.19 12.0 1.3 47 4.4 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2497) DUF1664 PF07889.10 001285595.1_09024001_2 - 0.32 10.9 7.9 1.2 9.1 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) KxDL PF10241.7 001285595.1_09024001_2 - 0.33 11.1 6.4 0.11 12.7 0.4 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein Pkinase PF00069.23 001314169.1_09024001_1 - 4.7e-31 108.0 0.0 7.6e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001314169.1_09024001_1 - 9.2e-26 90.5 0.0 1.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.21 001314169.1_09024001_1 - 1.7e-09 38.4 11.1 1.7e-09 38.4 11.1 1.7 2 0 0 2 2 2 1 Activin types I and II receptor domain Toxin_1 PF00087.19 001314169.1_09024001_1 - 0.057 13.5 8.5 0.15 12.1 8.5 1.7 1 0 0 1 1 1 0 Snake toxin ABC2_membrane PF01061.22 001285707.1_09025001_3 - 4.5e-40 137.2 20.1 4.5e-40 137.2 20.1 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.25 001285707.1_09025001_3 - 1e-22 81.0 0.0 1.8e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.17 001285707.1_09025001_3 - 9e-06 25.1 0.4 0.082 12.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.4 001285707.1_09025001_3 - 7.3e-05 22.6 6.6 0.058 13.1 0.2 2.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.4 001285707.1_09025001_3 - 0.0031 17.9 0.3 0.0031 17.9 0.3 2.3 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.14 001285707.1_09025001_3 - 0.014 15.2 0.0 0.048 13.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Adeno_IVa2 PF02456.13 001285707.1_09025001_3 - 0.12 11.1 0.3 0.47 9.1 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_29 PF13555.4 001285707.1_09025001_3 - 0.13 11.9 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.5 001285707.1_09025001_3 - 0.37 9.7 29.7 3.8 6.4 29.7 2.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF1774 PF08611.8 001285707.1_09025001_3 - 0.73 10.1 6.7 1.8 8.8 6.7 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1774) SpecificRecomb PF10136.7 001285707.1_09025001_3 - 1.9 6.6 5.9 2.9 6.0 5.9 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF2070 PF09843.7 001285707.1_09025001_3 - 5.2 5.1 15.5 8.4 4.4 15.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RrnaAD PF00398.18 001285600.1_09024001_2 - 1.2e-64 217.8 0.0 1.6e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.4 001285600.1_09024001_2 - 3e-07 30.9 0.0 5.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 001285600.1_09024001_2 - 8.4e-05 23.0 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.17 001285600.1_09024001_2 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.14 001285600.1_09024001_2 - 0.013 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.4 001285600.1_09024001_2 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.16 001285600.1_09024001_2 - 0.023 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_12 PF08242.10 001285600.1_09024001_2 - 0.024 15.2 0.0 0.048 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.5 001285600.1_09024001_2 - 0.036 13.9 0.1 0.079 12.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.18 001285600.1_09024001_2 - 0.066 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.12 001285600.1_09024001_2 - 0.088 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Fibrinogen_C PF00147.16 001285709.1_09024001_1 - 1.1e-52 178.9 5.7 1.4e-52 178.5 5.7 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF1664 PF07889.10 001285709.1_09024001_1 - 0.02 14.7 1.6 0.02 14.7 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4726 PF15855.3 001285709.1_09024001_1 - 0.21 11.7 0.2 0.42 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) V_ATPase_I PF01496.17 001285709.1_09024001_1 - 0.86 7.3 11.6 1.3 6.7 11.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.14 001285709.1_09024001_1 - 1 8.1 9.2 1.4 7.6 9.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HrpB2 PF09487.8 001285709.1_09024001_1 - 1.1 9.5 5.6 3.4 8.0 0.5 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) Sec34 PF04136.13 001285709.1_09024001_1 - 2.2 8.0 18.9 1 9.1 5.3 2.8 1 1 2 3 3 3 0 Sec34-like family USP8_interact PF08941.8 001285709.1_09024001_1 - 2.8 7.6 11.8 0.85 9.3 2.2 2.3 2 0 0 2 2 2 0 USP8 interacting SlyX PF04102.10 001285709.1_09024001_1 - 2.9 8.5 20.8 0.053 14.0 6.9 3.1 1 1 2 3 3 3 0 SlyX NPV_P10 PF05531.10 001285709.1_09024001_1 - 3.9 7.9 16.8 11 6.5 3.5 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein FHIPEP PF00771.18 001285709.1_09024001_1 - 6 5.1 10.8 8.3 4.6 10.8 1.1 1 0 0 1 1 1 0 FHIPEP family HemX PF04375.12 001285709.1_09024001_1 - 8.5 5.4 19.9 1.7 7.7 12.0 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Lys PF00062.18 001285711.1_09021001_1 - 7.2e-58 194.1 2.9 8.1e-58 193.9 2.9 1.0 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.18 001285711.1_09021001_1 - 0.00038 20.0 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain An_peroxidase PF03098.13 001314186.1_09025001_1 - 9e-180 598.6 0.0 1.1e-179 598.3 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Integrin_alpha2 PF08441.10 001314184.1_09027001_1 - 2.8e-123 412.1 0.0 3.4e-123 411.8 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.21 001314184.1_09027001_1 - 1.5e-27 95.2 28.7 9.9e-08 31.9 3.0 4.8 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.4 001314184.1_09027001_1 - 3.2e-15 56.3 11.4 6.8e-05 23.3 0.2 4.9 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.18 001314184.1_09027001_1 - 7.3e-05 22.3 0.7 0.00017 21.2 0.7 1.7 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.3 001314184.1_09027001_1 - 0.0003 20.3 0.0 0.00045 19.8 0.0 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family TGF_beta PF00019.18 001285606.1_09023001_1 - 5.4e-14 52.8 0.0 1.4e-13 51.5 0.0 1.7 1 1 0 1 1 1 1 Transforming growth factor beta like domain Pkinase PF00069.23 001285608.1_09023001_1 - 8.8e-79 264.4 0.0 1e-78 264.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001285608.1_09023001_1 - 2.2e-35 122.1 0.0 3.3e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001285608.1_09023001_1 - 0.0034 16.6 0.0 0.1 11.8 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.21 001285608.1_09023001_1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MtN3_slv PF03083.14 001314194.1_09022001_1 - 8.7e-58 192.2 7.0 7.3e-30 102.7 0.8 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.12 001314194.1_09022001_1 - 0.2 11.3 0.1 0.2 11.3 0.1 3.2 5 0 0 5 5 5 0 PQ loop repeat Filament PF00038.19 001285717.1_09024001_3 - 1.7e-109 366.0 36.4 2e-109 365.8 36.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.10 001285717.1_09024001_3 - 0.0093 15.9 3.8 0.0093 15.9 3.8 3.8 3 2 1 4 4 4 2 TPR/MLP1/MLP2-like protein Lzipper-MIP1 PF14389.4 001285717.1_09024001_3 - 0.014 15.5 4.0 0.014 15.5 4.0 4.2 4 1 1 5 5 4 0 Leucine-zipper of ternary complex factor MIP1 Uso1_p115_C PF04871.11 001285717.1_09024001_3 - 0.17 12.1 20.3 0.18 12.0 3.5 3.0 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.10 001285717.1_09024001_3 - 0.21 11.4 16.0 0.76 9.6 0.6 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.10 001285717.1_09024001_3 - 0.52 10.2 18.7 5.7 6.8 1.7 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.3 001285717.1_09024001_3 - 0.84 9.9 18.6 0.23 11.7 4.7 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) CREPT PF16566.3 001285717.1_09024001_3 - 1.1 9.3 20.9 2.6 8.1 2.4 3.4 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF342 PF03961.11 001285717.1_09024001_3 - 4.2 5.7 19.4 0.37 9.2 8.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) NYD-SP28_assoc PF14775.4 001285717.1_09024001_3 - 4.2 7.4 10.8 4.7 7.2 1.0 4.0 3 1 0 3 3 3 0 Sperm tail C-terminal domain Spc7 PF08317.9 001285717.1_09024001_3 - 4.4 6.0 30.7 2.3 6.9 10.2 2.6 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.4 001285717.1_09024001_3 - 5.4 6.1 17.8 13 4.9 3.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.6 001285717.1_09024001_3 - 8.7 6.3 32.0 6.1 6.8 13.8 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.8 001285717.1_09024001_3 - 8.8 6.4 26.2 0.76 9.8 8.1 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family ERM PF00769.17 001285717.1_09024001_3 - 9.2 5.9 24.5 1.1 8.9 17.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family MAPEG PF01124.16 001285615.1_09021001_1 - 1.3e-24 86.4 0.5 1.6e-24 86.1 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Asp PF00026.21 001285720.1_09023001_1 - 1.5e-101 339.8 0.0 1.8e-101 339.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285720.1_09023001_1 - 6.6e-14 52.4 0.2 2.9e-11 43.8 0.2 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001285720.1_09023001_1 - 9.3e-10 38.0 1.6 1.6e-09 37.3 1.6 1.4 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.4 001285720.1_09023001_1 - 0.013 16.0 0.1 2.6 8.6 0.0 3.2 2 1 0 2 2 2 0 Aspartyl protease Cathelicidins PF00666.15 001285620.1_09023001_1 - 2.3e-44 149.7 0.7 3.5e-44 149.1 0.2 1.6 2 0 0 2 2 2 1 Cathelicidin CAP18_C PF12153.6 001285620.1_09023001_1 - 3.1e-10 39.7 7.5 3.1e-10 39.7 7.5 1.5 2 0 0 2 2 2 1 LPS binding domain of CAP18 (C terminal) Spp-24 PF07448.9 001285620.1_09023001_1 - 0.0021 18.0 0.2 0.0052 16.8 0.2 1.6 1 0 0 1 1 1 1 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Lipocalin PF00061.21 001285623.1_09021001_1 - 5.9e-28 97.7 1.0 6.5e-28 97.6 1.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.4 001285623.1_09021001_1 - 5.6e-07 29.4 1.2 7.1e-07 29.1 1.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Asp PF00026.21 001285722.1_09023001_1 - 1.4e-104 349.8 0.0 1.6e-104 349.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285722.1_09023001_1 - 6e-17 62.3 3.4 3.2e-09 37.2 0.1 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.4 001285722.1_09023001_1 - 7e-05 23.3 0.2 2.5 8.7 0.1 3.8 3 1 0 3 3 3 2 Aspartyl protease A1_Propeptide PF07966.10 001285722.1_09023001_1 - 0.00034 20.3 0.1 0.00059 19.5 0.1 1.4 1 0 0 1 1 1 1 A1 Propeptide Troponin PF00992.18 001314210.1_09022001_1 - 6.2e-32 110.6 34.7 6.2e-32 110.6 34.7 3.0 2 1 1 3 3 3 2 Troponin S6OS1 PF15676.3 001314210.1_09022001_2 - 1.5 7.1 6.2 2.1 6.6 6.2 1.2 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Furin-like_2 PF15913.3 001285627.1_09023001_2 - 2.5e-46 156.1 19.9 2.5e-46 156.1 19.9 1.8 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich IL17 PF06083.9 001285725.1_09023001_2 - 7.7e-29 99.9 1.6 1.3e-28 99.1 1.6 1.4 1 0 0 1 1 1 1 Interleukin-17 SLC3A2_N PF16028.3 001285725.1_09023001_2 - 0.031 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus SLAM PF06214.9 001285726.1_09023001_1 - 4.7e-59 197.7 0.8 8e-59 197.0 0.8 1.4 1 0 0 1 1 1 1 Signaling lymphocytic activation molecule (SLAM) protein Ig_3 PF13927.4 001285726.1_09023001_1 - 1.9e-05 25.1 0.3 0.0026 18.2 0.2 2.7 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.15 001285726.1_09023001_1 - 0.00072 19.5 0.1 0.0027 17.7 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.6 001285726.1_09023001_1 - 0.034 14.2 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Acyl_transf_1 PF00698.19 001285629.1_09029001_2 - 6.7e-107 357.5 0.0 1.3e-106 356.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.24 001285629.1_09029001_2 - 9.1e-70 235.0 0.1 1.6e-69 234.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.18 001285629.1_09029001_2 - 2.5e-57 194.5 0.2 8.5e-57 192.8 0.3 1.9 2 0 0 2 2 2 1 Thioesterase domain KR PF08659.8 001285629.1_09029001_2 - 4.8e-50 169.8 0.0 9.2e-50 168.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.20 001285629.1_09029001_2 - 7.9e-37 125.7 0.0 1.7e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.3 001285629.1_09029001_2 - 6.3e-34 116.7 0.0 1.8e-33 115.2 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.24 001285629.1_09029001_2 - 2.5e-18 66.1 0.0 1.1e-17 64.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PS-DH PF14765.4 001285629.1_09029001_2 - 3.7e-16 59.1 0.0 7.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.4 001285629.1_09029001_2 - 2e-15 57.9 0.0 6.6e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.23 001285629.1_09029001_2 - 8.5e-10 38.7 0.5 2e-09 37.5 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.23 001285629.1_09029001_2 - 1.3e-08 34.4 0.0 4e-07 29.5 0.0 3.1 4 0 0 4 4 4 1 short chain dehydrogenase Methyltransf_23 PF13489.4 001285629.1_09029001_2 - 8.9e-07 28.8 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.10 001285629.1_09029001_2 - 1.5e-06 28.7 0.0 4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.4 001285629.1_09029001_2 - 6e-05 22.7 0.0 0.00017 21.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.21 001285629.1_09029001_2 - 0.00034 19.9 0.0 0.00068 18.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.10 001285629.1_09029001_2 - 0.0039 17.6 0.0 0.026 15.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain YjeF_N PF03853.13 001285629.1_09029001_2 - 0.0092 15.7 0.2 0.48 10.1 0.0 2.7 2 0 0 2 2 2 1 YjeF-related protein N-terminus Sugar_tr PF00083.22 001314223.1_09025001_2 - 2.3e-159 531.0 23.3 2.9e-159 530.6 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001314223.1_09025001_2 - 6.3e-21 74.6 25.8 4.2e-18 65.3 24.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2127 PF09900.7 001314223.1_09025001_2 - 0.021 15.0 1.4 0.06 13.5 1.4 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) DUF523 PF04463.10 001314223.1_09025001_2 - 0.14 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF523) Hanta_G1 PF01567.14 001314223.1_09025001_2 - 0.19 10.3 1.7 2.5 6.6 1.7 2.3 2 0 0 2 2 2 0 Hantavirus glycoprotein G1 TRI12 PF06609.11 001314223.1_09025001_2 - 0.24 9.6 7.2 0.014 13.7 1.5 1.7 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pox_EPC_I2-L1 PF12575.6 001314223.1_09025001_2 - 2.1 8.5 5.9 0.46 10.6 1.2 2.4 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Lipocalin PF00061.21 001285630.1_09022001_1 - 3.1e-11 43.5 0.3 4.1e-11 43.1 0.3 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family OTCace PF00185.22 001285729.1_09023001_3 - 3.9e-51 173.1 0.0 5.5e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.19 001285729.1_09023001_3 - 1.6e-41 141.5 0.0 2.6e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Lipocalin PF00061.21 001314229.1_09022001_2 - 5.3e-22 78.4 0.0 6.7e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.10 001314229.1_09022001_2 - 5e-06 26.4 0.0 7.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.11 001314229.1_09022001_2 - 0.022 14.5 0.3 0.066 12.9 0.3 1.7 1 1 0 1 1 1 0 Triabin HSP70 PF00012.18 001314233.1_09024001_1 - 3.4e-263 874.2 12.7 3.8e-263 874.0 12.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001314233.1_09024001_1 - 3.5e-19 68.6 0.4 1.1e-17 63.7 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.14 001314233.1_09024001_1 - 0.0016 18.1 0.0 0.0045 16.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.4 001314233.1_09024001_1 - 0.005 17.1 6.1 1.3 9.4 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.18 001314233.1_09024001_1 - 0.011 15.1 0.2 4.4 6.6 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.8 001314233.1_09024001_1 - 0.033 13.0 0.3 0.18 10.6 0.3 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HORMA PF02301.16 001314233.1_09024001_1 - 0.07 12.6 1.4 0.17 11.3 1.4 1.6 1 0 0 1 1 1 0 HORMA domain Radial_spoke_3 PF06098.9 001314233.1_09024001_1 - 1.9 7.5 12.5 0.22 10.6 8.3 1.5 2 0 0 2 2 2 0 Radial spoke protein 3 Membralin PF09746.7 001314233.1_09024001_1 - 4.8 6.0 5.0 8.4 5.2 5.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein Basic PF01586.14 001285733.1_09022001_2 - 2.9e-25 89.1 0.0 6e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Myogenic Basic domain HLH PF00010.24 001285733.1_09022001_2 - 2.2e-12 46.6 5.4 4e-12 45.8 5.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3080 PF11279.6 001285733.1_09022001_2 - 0.0061 15.7 0.2 0.0082 15.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) TNFR_c6 PF00020.16 001314235.1_09023001_3 - 3.8e-15 55.9 49.4 1.7e-09 37.8 11.2 3.6 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region Death PF00531.20 001314235.1_09023001_3 - 4.8e-12 45.8 0.1 8.3e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Death domain DUF4381 PF14316.4 001314235.1_09023001_3 - 0.0042 17.2 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) P12 PF12669.5 001314235.1_09023001_3 - 0.0063 16.8 0.8 0.0063 16.8 0.8 4.5 3 1 0 3 3 3 1 Virus attachment protein p12 family Stn1_C PF12659.5 001314235.1_09023001_3 - 0.026 14.3 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH RIO1 PF01163.20 001314235.1_09023001_3 - 0.072 12.5 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 RIO1 family CcmH PF03918.12 001314235.1_09023001_3 - 0.096 11.8 0.4 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Rifin_STEVOR PF02009.14 001314235.1_09023001_3 - 1.9 8.2 13.3 0.54 10.0 8.8 2.2 2 1 0 2 2 2 0 Rifin/stevor family 7tm_1 PF00001.19 001314237.1_09029001_1 - 4.3e-59 199.8 22.7 4.3e-59 199.8 22.7 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001314237.1_09029001_1 - 1.9e-10 40.5 22.5 3.1e-10 39.7 22.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Troponin PF00992.18 001314239.1_09022001_2 - 5.2e-44 149.7 7.5 9.6e-44 148.8 7.5 1.4 1 0 0 1 1 1 1 Troponin Troponin-I_N PF11636.6 001314239.1_09022001_2 - 9.3e-14 50.9 9.9 1.8e-13 50.0 9.9 1.5 1 0 0 1 1 1 1 Troponin I residues 1-32 DUF919 PF06034.9 001314239.1_09022001_2 - 0.0046 16.6 0.1 0.0046 16.6 0.1 2.3 3 1 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF919) Tup_N PF08581.8 001314239.1_09022001_2 - 0.008 16.3 0.1 0.008 16.3 0.1 2.1 3 0 0 3 3 3 1 Tup N-terminal INSIG PF07281.10 001285738.1_09022001_2 - 1.3e-47 162.1 6.5 7.1e-47 159.6 6.5 2.0 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) SLAC1 PF03595.15 001285738.1_09022001_2 - 0.0062 15.8 7.5 0.017 14.4 7.5 1.7 1 1 0 1 1 1 1 Voltage-dependent anion channel DUF202 PF02656.13 001285738.1_09022001_2 - 7.4 7.0 10.2 1.2 9.4 1.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Gal-bind_lectin PF00337.20 001285650.1_09021001_2 - 9e-22 76.9 0.0 1.1e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin AT_hook PF02178.17 001285651.1_09021001_1 - 9.5e-06 24.8 36.1 0.0042 16.7 2.3 4.1 4 0 0 4 4 4 3 AT hook motif Thyroglobulin_1 PF00086.16 001314243.1_09022001_1 - 1.2e-17 63.1 3.6 1.2e-17 63.1 3.6 2.5 2 1 0 2 2 2 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001314243.1_09022001_1 - 6.9e-06 26.5 18.3 6.9e-06 26.5 18.3 2.3 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Patatin PF01734.20 001285739.1_09025001_1 - 4.3e-15 56.3 1.0 8.1e-08 32.5 0.5 2.4 2 0 0 2 2 2 2 Patatin-like phospholipase Peptidase_C1 PF00112.21 001314245.1_09023001_2 - 2.4e-65 220.6 4.1 2.9e-65 220.3 4.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.11 001314245.1_09023001_2 - 1e-19 70.0 0.1 1.8e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.13 001314245.1_09023001_2 - 0.0029 16.3 1.0 0.076 11.6 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family FOXP-CC PF16159.3 001285654.1_09025001_1 - 3.4e-35 120.3 4.2 3.4e-35 120.3 4.2 4.6 3 1 2 5 5 5 1 FOXP coiled-coil domain Forkhead PF00250.16 001285654.1_09025001_1 - 2.9e-28 97.9 0.2 1.1e-27 96.0 0.2 2.0 1 0 0 1 1 1 1 Forkhead domain Plasmodium_Vir PF05795.9 001285654.1_09025001_1 - 0.11 11.8 8.0 0.2 10.9 6.0 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein hDGE_amylase PF14701.4 001285654.1_09025001_1 - 0.57 9.0 17.4 1.2 8.0 17.4 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF2347 PF09804.7 001285654.1_09025001_1 - 2 7.8 12.6 4.5 6.6 12.6 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) TT_ORF1 PF02956.12 001285654.1_09025001_1 - 3.9 5.9 21.6 6.3 5.2 21.6 1.2 1 0 0 1 1 1 0 TT viral orf 1 GAGA_bind PF06217.10 001285654.1_09025001_1 - 5.4 7.1 21.3 2.3 8.3 17.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Rxt3 PF08642.8 001285654.1_09025001_1 - 8.7 7.0 10.6 40 4.8 10.6 2.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF4282 PF14110.4 001285740.1_09025001_1 - 0.1 13.2 1.1 0.19 12.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) HMG_CoA_synt_C PF08540.8 001285740.1_09025001_3 - 3.1e-125 417.3 1.3 4e-125 416.9 1.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.15 001285740.1_09025001_3 - 3.5e-105 349.2 0.2 4.9e-105 348.7 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.8 001285740.1_09025001_3 - 0.0076 15.9 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADK PF00406.20 001314253.1_09024001_3 - 6.9e-43 146.2 0.0 9.1e-43 145.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.4 001314253.1_09024001_3 - 3.4e-37 127.8 0.0 4.6e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001314253.1_09024001_3 - 4.6e-07 30.3 0.1 1.2e-06 28.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.15 001314253.1_09024001_3 - 2.1e-06 27.4 0.1 0.012 15.2 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.10 001314253.1_09024001_3 - 0.00024 20.3 0.0 0.00037 19.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.4 001314253.1_09024001_3 - 0.00065 19.7 0.0 0.0011 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.16 001314253.1_09024001_3 - 0.23 11.0 0.2 5.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase Ig_2 PF13895.4 001285742.1_09022001_1 - 4.9e-16 58.7 0.0 3.5e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001285742.1_09022001_1 - 2.5e-09 37.5 0.0 1.2e-05 25.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001285742.1_09022001_1 - 7.9e-06 25.8 0.2 0.0014 18.7 0.0 2.8 3 1 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.3 001285742.1_09022001_1 - 0.067 13.1 0.0 52 3.9 0.0 3.2 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain V-set PF07686.15 001285742.1_09022001_1 - 0.1 12.7 0.1 10 6.2 0.0 2.7 2 1 1 3 3 3 0 Immunoglobulin V-set domain Ras PF00071.20 001285659.1_09022001_1 - 7.9e-61 204.2 0.1 9.2e-61 204.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001285659.1_09022001_1 - 3.9e-32 110.9 0.0 5.9e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001285659.1_09022001_1 - 1.5e-12 47.2 0.0 2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001285659.1_09022001_1 - 2.6e-05 23.7 0.0 0.0012 18.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001285659.1_09022001_1 - 4.3e-05 23.4 0.0 7.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001285659.1_09022001_1 - 0.00029 20.7 0.1 0.59 9.9 0.0 2.2 1 1 0 2 2 2 2 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001285659.1_09022001_1 - 0.0013 18.0 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.15 001285659.1_09022001_1 - 0.0033 17.1 0.0 0.11 12.1 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.8 001285659.1_09022001_1 - 0.05 12.9 0.0 0.071 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1863 PF08937.9 001285659.1_09022001_1 - 0.051 13.8 0.0 0.088 13.0 0.0 1.5 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) AAA PF00004.27 001285659.1_09022001_1 - 0.1 12.9 0.0 0.43 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.16 001285659.1_09022001_1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.4 001285659.1_09022001_1 - 0.13 12.4 0.1 0.62 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Homeobox PF00046.27 001314259.1_09022001_1 - 8.4e-23 79.8 9.2 1.4e-22 79.1 9.2 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.15 001314259.1_09022001_1 - 8.4e-09 34.8 1.1 1.9e-08 33.7 1.1 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.9 001314259.1_09022001_1 - 0.0041 16.9 0.6 0.0041 16.9 0.6 2.3 2 1 0 2 2 2 1 Homeobox KN domain XRCC4 PF06632.10 001314259.1_09022001_1 - 0.012 14.4 3.5 0.016 14.0 3.5 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Crisp PF08562.8 001285744.1_09022001_3 - 2.9e-19 69.3 21.2 7.7e-19 67.9 21.2 1.8 1 0 0 1 1 1 1 Crisp CAP PF00188.24 001285744.1_09022001_3 - 9.6e-14 52.2 2.0 9.6e-14 52.2 2.0 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Bax1-I PF01027.18 001285661.1_09023001_1 - 6.8e-41 140.2 14.4 6.8e-41 140.2 14.4 1.3 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF3021 PF11457.6 001285661.1_09023001_1 - 1.8 8.8 9.4 9.1 6.5 4.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Glycos_transf_2 PF00535.24 001314262.1_09024001_1 - 1.4e-17 63.8 0.0 2.5e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_5 PF13712.4 001314262.1_09024001_1 - 0.019 14.6 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family Glyco_tranf_2_3 PF13641.4 001314262.1_09024001_1 - 0.04 13.7 0.0 0.15 11.8 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase like family 2 SPARC_Ca_bdg PF10591.7 001285662.1_09022001_1 - 2.2e-40 137.4 0.2 5.4e-40 136.1 0.2 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.19 001285662.1_09022001_1 - 1.2e-13 50.7 4.4 1.2e-13 50.7 4.4 2.6 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 001285662.1_09022001_1 - 1.4e-11 44.2 2.2 5.1e-11 42.4 2.2 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain FOLN PF09289.8 001285662.1_09022001_1 - 2.3e-10 40.3 6.4 2.3e-10 40.3 6.4 2.1 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.30 001285662.1_09022001_1 - 0.047 13.1 0.1 0.42 10.1 0.1 2.4 2 0 0 2 2 2 0 EF hand hEGF PF12661.5 001285662.1_09022001_1 - 0.056 14.0 1.4 0.24 12.0 1.4 2.2 1 1 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.25 001285662.1_09022001_1 - 1.7 8.9 8.3 7.2 6.9 8.3 2.1 1 1 0 1 1 1 0 EGF-like domain Peptidase_C2 PF00648.19 001285663.1_09025001_1 - 5.6e-129 429.3 0.0 9.5e-129 428.5 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.20 001285663.1_09025001_1 - 4.2e-53 179.3 0.0 1.4e-52 177.6 0.0 1.9 2 0 0 2 2 2 1 Calpain large subunit, domain III EF-hand_8 PF13833.4 001285663.1_09025001_1 - 7.7e-14 51.1 7.8 1.1e-10 41.0 0.1 4.1 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.4 001285663.1_09025001_1 - 2.9e-10 39.1 6.1 0.0061 16.3 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.30 001285663.1_09025001_1 - 4.3e-10 38.3 5.7 0.01 15.2 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.4 001285663.1_09025001_1 - 5.4e-08 33.1 5.9 0.028 14.7 1.4 4.1 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.4 001285663.1_09025001_1 - 0.1 12.0 7.9 2.1 7.9 0.0 4.4 4 0 0 4 4 4 0 EF hand Zip PF02535.20 001285666.1_09023001_3 - 7.8e-56 189.6 16.2 4.2e-34 118.1 10.2 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Pkinase PF00069.23 001285750.1_09023001_1 - 3.7e-77 259.1 0.0 4.8e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001285750.1_09023001_1 - 8.2e-36 123.5 0.0 1.3e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.27 001285750.1_09023001_1 - 8.9e-17 61.4 0.2 2e-16 60.2 0.2 1.7 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.22 001285750.1_09023001_1 - 1.5e-10 41.4 3.7 3.2e-10 40.4 3.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.4 001285750.1_09023001_1 - 2.3e-08 33.6 0.0 7.7e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PH_11 PF15413.4 001285750.1_09023001_1 - 0.02 15.2 0.5 0.087 13.1 0.0 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain Seadorna_VP7 PF07387.9 001285750.1_09023001_1 - 0.044 12.7 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.21 001285750.1_09023001_1 - 0.093 12.5 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Tetraspannin PF00335.18 001285671.1_09023001_1 - 5.4e-45 153.7 9.9 5.4e-45 153.7 9.9 1.4 2 0 0 2 2 2 1 Tetraspanin family DUF2371 PF10177.7 001285671.1_09023001_1 - 0.3 11.1 1.7 4.2 7.4 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) TNFR_c6 PF00020.16 001314281.1_09023001_1 - 7.3e-24 83.8 44.9 5.9e-09 36.1 5.5 4.8 3 1 0 4 4 4 4 TNFR/NGFR cysteine-rich region Ets PF00178.20 001314285.1_09022001_1 - 4.5e-30 103.8 0.4 1e-29 102.7 0.4 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.14 001314285.1_09022001_1 - 1.3e-27 95.5 0.7 2.2e-27 94.7 0.7 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Endothelin PF00322.15 001314285.1_09022001_1 - 4.3 6.9 8.3 1.3 8.6 4.7 2.0 2 0 0 2 2 2 0 Endothelin family Aldo_ket_red PF00248.19 001314287.1_09023001_3 - 1.8e-55 188.0 0.0 2.7e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family IDO PF01231.16 001314289.1_09023001_1 - 3.2e-121 405.0 0.0 3.9e-121 404.7 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.9 001314289.1_09023001_1 - 0.0018 16.9 0.3 0.021 13.4 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1864) Mannosyl_trans4 PF15971.3 001314289.1_09023001_1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase IL22 PF14565.4 001285758.1_09023001_1 - 1.5e-59 200.1 0.8 2e-59 199.7 0.8 1.2 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL10 PF00726.15 001285758.1_09023001_1 - 0.00017 21.0 0.6 0.00025 20.5 0.6 1.2 1 0 0 1 1 1 1 Interleukin 10 Asp PF00026.21 001285759.1_09023001_2 - 4.7e-118 394.0 2.6 5.5e-118 393.8 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285759.1_09023001_2 - 6.5e-13 49.2 0.4 2e-09 37.9 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001285759.1_09023001_2 - 4.4e-11 42.3 0.3 7.5e-11 41.5 0.3 1.4 1 0 0 1 1 1 1 A1 Propeptide Acyltransferase PF01553.19 001285761.1_09025001_2 - 4e-33 113.8 0.0 5.9e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Thyroglobulin_1 PF00086.16 001314299.1_09023001_1 - 2.3e-17 62.3 0.9 2.3e-17 62.3 0.9 2.1 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001314299.1_09023001_1 - 3.2e-11 43.5 19.7 3.2e-11 43.5 19.7 2.5 2 0 0 2 2 2 1 Insulin-like growth factor binding protein DAGAT PF03982.11 001314305.1_09023001_1 - 7.2e-145 481.3 0.0 8.7e-145 481.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.19 001314305.1_09023001_1 - 0.091 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase Cnl2_NKP2 PF09447.8 001314305.1_09023001_3 - 0.21 11.6 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Kazal_2 PF07648.13 001285764.1_09023001_1 - 4.4e-36 122.7 32.2 1.5e-13 50.6 1.4 4.6 4 1 0 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.19 001285764.1_09023001_1 - 1.7e-19 69.4 34.8 2.6e-07 30.4 4.2 4.0 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain FOLN PF09289.8 001285764.1_09023001_1 - 4.7e-07 29.7 12.7 4.7e-07 29.7 12.7 4.7 4 1 0 4 4 4 1 Follistatin/Osteonectin-like EGF domain Thyroglobulin_1 PF00086.16 001285763.1_09022001_3 - 2.3e-22 78.3 2.5 3.7e-22 77.6 2.5 1.3 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat IGFBP PF00219.16 001285763.1_09022001_3 - 3.5e-08 33.8 20.3 3.5e-08 33.8 20.3 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein DFF-C PF09033.8 001285763.1_09022001_3 - 0.034 13.9 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Peptidase_M10 PF00413.22 001285765.1_09024001_2 - 3.4e-58 195.8 0.0 5.7e-58 195.1 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.17 001285765.1_09024001_2 - 1.3e-55 185.0 15.6 7.7e-14 51.2 0.2 4.9 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.6 001285765.1_09024001_2 - 1.2e-24 85.9 0.0 2.7e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.16 001285765.1_09024001_2 - 1.7e-11 44.0 0.1 3.9e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.22 001285765.1_09024001_2 - 0.0009 18.8 0.6 0.35 10.3 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.9 001285765.1_09024001_2 - 0.0072 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M54 Metallopep PF12044.6 001285765.1_09024001_2 - 0.023 13.2 0.0 0.033 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family DUF4953 PF16313.3 001285765.1_09024001_2 - 0.027 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Met-zincin HTH_17 PF12728.5 001285765.1_09024001_2 - 0.085 12.9 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Reprolysin_3 PF13582.4 001285765.1_09024001_2 - 0.11 12.9 0.3 0.19 12.1 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.7 001285765.1_09024001_2 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 SKG6 PF08693.8 001285765.1_09024001_2 - 0.16 11.3 3.8 0.35 10.2 3.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Surfac_D-trimer PF09006.9 001314318.1_09023001_1 - 3.5e-27 93.9 0.4 6.5e-27 93.0 0.4 1.5 1 0 0 1 1 1 1 Lung surfactant protein D coiled-coil trimerisation Collagen PF01391.16 001314318.1_09023001_1 - 2.6e-25 87.8 109.8 2e-09 36.9 29.2 3.6 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) Lectin_C PF00059.19 001314318.1_09023001_1 - 1.5e-20 73.8 0.2 2e-20 73.4 0.2 1.2 1 0 0 1 1 1 1 Lectin C-type domain GST_C PF00043.23 001314321.1_09022001_1 - 1.6e-20 73.0 0.0 2.7e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001314321.1_09022001_1 - 2.7e-20 72.3 0.0 4.2e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001314321.1_09022001_1 - 7.3e-19 67.8 0.0 2e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001314321.1_09022001_1 - 0.036 13.9 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001314321.1_09022001_1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Zip PF02535.20 001285772.1_09023001_2 - 2.3e-64 217.6 14.0 6.5e-62 209.5 14.0 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2461 PF09365.8 001285772.1_09023001_2 - 0.054 13.3 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) zf-LITAF-like PF10601.7 001285772.1_09023001_2 - 0.77 9.9 4.3 0.43 10.8 1.1 2.2 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain SSF PF00474.15 001314323.1_09024001_1 - 6.7e-171 568.5 24.6 6.7e-171 568.5 24.6 2.1 2 0 0 2 2 2 1 Sodium:solute symporter family TadF PF16964.3 001314323.1_09024001_1 - 0.0035 17.0 0.0 0.0035 17.0 0.0 1.7 2 0 0 2 2 2 1 Putative tight adherence pilin protein F Toxin_2 PF00451.17 001314323.1_09024001_1 - 0.57 10.4 3.5 1.9 8.8 3.5 1.9 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 Ribosomal_L10 PF00466.18 001314331.1_09022001_1 - 2.8e-22 78.6 0.0 5.5e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.17 001314331.1_09022001_1 - 4.7e-21 75.0 5.8 4.7e-21 75.0 5.8 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein TraL PF07178.9 001314331.1_09022001_2 - 0.064 13.6 0.5 0.13 12.6 0.5 1.4 1 0 0 1 1 1 0 TraL protein Ery_res_leader1 PF08051.9 001314340.1_09027001_1 - 0.071 13.0 0.3 0.37 10.8 0.3 2.4 1 0 0 1 1 1 0 Erythromycin resistance leader peptide Glyco_hydro_38C PF07748.11 001314340.1_09027001_2 - 1.5e-104 350.4 0.0 1.9e-104 350.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38 PF01074.20 001314340.1_09027001_2 - 3.7e-96 321.7 3.5 5e-96 321.3 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.9 001314340.1_09027001_2 - 3.9e-20 71.9 0.0 8.9e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_transf_7N PF13733.4 001285775.1_09024001_2 - 1.5e-59 199.3 0.1 2.1e-59 198.9 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.12 001285775.1_09024001_2 - 1.9e-29 101.0 0.1 3.5e-29 100.1 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.7 001285775.1_09024001_2 - 0.0033 16.8 0.0 0.0084 15.5 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase like family 2 S10_plectin PF03501.13 001286087.1_09022001_2 - 3.2e-50 168.1 0.2 3.9e-50 167.8 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ras PF00071.20 001286091.1_09024001_1 - 3.6e-57 192.3 0.1 4.6e-57 192.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001286091.1_09024001_1 - 2.6e-31 108.2 0.0 3.8e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001286091.1_09024001_1 - 2.6e-12 46.4 0.0 3.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001286091.1_09024001_1 - 1.6e-06 28.1 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001286091.1_09024001_1 - 4.2e-05 22.9 0.0 5.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.14 001286091.1_09024001_1 - 5.5e-05 23.0 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001286091.1_09024001_1 - 0.00051 19.5 0.0 0.0082 15.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.16 001286091.1_09024001_1 - 0.028 13.5 0.2 0.088 11.9 0.1 1.7 2 0 0 2 2 2 0 Septin cobW PF02492.17 001286091.1_09024001_1 - 0.029 13.8 0.0 0.061 12.8 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.4 001286091.1_09024001_1 - 0.039 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.4 001286091.1_09024001_1 - 0.084 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.7 001286091.1_09024001_1 - 0.086 12.5 0.1 0.47 10.1 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.8 001286091.1_09024001_1 - 0.096 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.4 001286091.1_09024001_1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.15 001286091.1_09024001_1 - 0.14 11.8 0.2 2.4 7.7 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.13 001286091.1_09024001_1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.12 001286091.1_09024001_1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Integrin_beta PF00362.16 001314348.1_09025001_1 - 2e-108 361.6 0.0 2.9e-108 361.1 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.9 001314348.1_09025001_1 - 3.9e-20 71.1 0.1 6.8e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.10 001314348.1_09025001_1 - 4.4e-16 59.0 7.4 4.4e-16 59.0 7.4 3.8 3 1 1 4 4 4 1 Integrin beta tail domain PSI_integrin PF17205.1 001314348.1_09025001_1 - 6.5e-15 54.6 4.0 6.5e-15 54.6 4.0 5.0 4 1 0 4 4 4 1 Integrin plexin domain EGF_2 PF07974.11 001314348.1_09025001_1 - 4.8e-10 39.5 89.8 0.00025 21.2 16.0 6.4 5 1 1 6 6 6 4 EGF-like domain ANF_receptor PF01094.26 001286092.1_09028001_1 - 1.9e-106 356.0 0.0 2.5e-106 355.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.20 001286092.1_09028001_1 - 3.9e-65 219.8 30.3 1.5e-64 217.9 29.5 2.0 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.12 001286092.1_09028001_1 - 1.6e-16 59.9 11.1 1.6e-16 59.9 11.1 2.7 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.4 001286092.1_09028001_1 - 2.5e-11 43.8 0.0 2.7e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 Periplasmic binding protein Ephrin_rec_like PF07699.11 001286092.1_09028001_1 - 0.0037 16.9 7.5 0.012 15.2 7.5 1.8 1 0 0 1 1 1 1 Putative ephrin-receptor like Ras PF00071.20 001286443.1_09023001_2 - 1.2e-57 193.9 0.0 1.6e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001286443.1_09023001_2 - 1e-22 80.5 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001286443.1_09023001_2 - 4.1e-09 36.0 0.0 7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001286443.1_09023001_2 - 0.0022 17.4 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Lys PF00062.18 001286975.1_09022001_1 - 2.1e-41 140.9 0.9 2.5e-41 140.7 0.9 1.1 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Ras PF00071.20 001286965.1_09023001_3 - 1.6e-66 222.7 1.1 2.1e-66 222.4 1.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001286965.1_09023001_3 - 1.6e-36 125.1 0.1 2.5e-36 124.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001286965.1_09023001_3 - 7.1e-17 61.3 0.1 1e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.14 001286965.1_09023001_3 - 9.3e-06 25.5 0.4 0.057 13.2 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF258 Gtr1_RagA PF04670.10 001286965.1_09023001_3 - 4.9e-05 22.7 0.1 6.7e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001286965.1_09023001_3 - 6.1e-05 22.5 0.2 0.00013 21.5 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001286965.1_09023001_3 - 8.8e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.8 001286965.1_09023001_3 - 9.6e-05 21.7 0.1 0.00015 21.1 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.27 001286965.1_09023001_3 - 0.018 15.3 0.0 0.74 10.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.16 001286965.1_09023001_3 - 0.042 13.3 0.0 0.15 11.5 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.4 001286965.1_09023001_3 - 0.083 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Thymosin PF01290.18 001287029.1_09022001_3 - 5.3e-22 77.1 10.6 7.4e-22 76.6 10.6 1.2 1 0 0 1 1 1 1 Thymosin beta-4 family WH2 PF02205.18 001287029.1_09022001_3 - 0.023 14.4 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 WH2 motif VEGF_C PF14554.4 001287034.1_09025001_1 - 7.5e-28 96.3 17.7 7.5e-28 96.3 17.7 2.0 2 0 0 2 2 2 1 VEGF heparin-binding domain PDGF PF00341.15 001287034.1_09025001_1 - 1.6e-26 92.3 6.3 1.6e-26 92.3 6.3 2.1 2 0 0 2 2 2 1 PDGF/VEGF domain RRT14 PF17075.3 001287034.1_09025001_2 - 0.013 15.5 0.2 0.018 15.0 0.2 1.1 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 VEGF_C PF14554.4 001287035.1_09025001_1 - 1.7e-27 95.2 20.2 1.7e-27 95.2 20.2 1.9 1 1 0 1 1 1 1 VEGF heparin-binding domain PDGF PF00341.15 001287035.1_09025001_1 - 1.5e-26 92.4 6.3 1.5e-26 92.4 6.3 2.0 2 0 0 2 2 2 1 PDGF/VEGF domain IGF2_C PF08365.9 001287041.1_09025001_2 - 2.3e-25 88.2 1.9 7e-25 86.7 1.9 1.9 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Insulin PF00049.16 001287041.1_09025001_2 - 7.7e-13 49.1 5.4 3.2e-06 27.9 2.0 2.5 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family Myf5 PF12232.6 001287037.1_09022001_1 - 6e-25 87.7 12.0 6e-25 87.7 12.0 2.3 2 0 0 2 2 2 1 Myogenic determination factor 5 Basic PF01586.14 001287037.1_09022001_1 - 8.1e-23 81.3 0.8 2.8e-22 79.6 0.8 2.0 1 0 0 1 1 1 1 Myogenic Basic domain HLH PF00010.24 001287037.1_09022001_1 - 2.7e-15 55.9 4.0 5.4e-15 55.0 4.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ELO PF01151.16 001287178.1_09022001_1 - 4.7e-64 216.2 20.8 5.8e-64 215.9 20.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family IZUMO PF15005.4 001287235.1_09022001_1 - 1.3e-59 200.8 3.4 2.1e-59 200.1 3.4 1.3 1 0 0 1 1 1 1 Izumo sperm-egg fusion, Ig domain-associated Izumo-Ig PF16706.3 001287235.1_09022001_1 - 1.2e-44 150.2 0.0 1.8e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Ig_2 PF13895.4 001287235.1_09022001_1 - 0.00023 21.3 0.1 0.00045 20.4 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain TMEM95 PF15203.4 001287235.1_09022001_1 - 0.0031 17.0 5.7 0.015 14.8 5.7 2.0 1 1 0 1 1 1 1 TMEM95 family V-set PF07686.15 001287235.1_09022001_1 - 0.042 13.9 0.0 0.28 11.2 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin V-set domain Kunitz_BPTI PF00014.21 001172836.1_09923001_2 - 4.5e-33 113.1 21.1 7.1e-17 61.3 5.1 2.4 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Lipocalin PF00061.21 001172836.1_09923001_2 - 4.4e-29 101.4 0.0 6.1e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family EF1_GNE PF00736.17 001314225.1_09023001_3 - 1.8e-36 124.0 1.0 3.3e-36 123.2 0.4 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.7 001314225.1_09023001_3 - 9.4e-12 45.0 6.7 9.4e-12 45.0 6.7 2.5 2 0 0 2 2 1 1 Eukaryotic elongation factor 1 beta central acidic region Striatin PF08232.10 001314225.1_09023001_3 - 0.00068 20.1 2.6 0.0013 19.2 2.6 1.4 1 0 0 1 1 1 1 Striatin family CCD48 PF15799.3 001314225.1_09023001_3 - 0.011 14.0 2.6 0.02 13.2 2.6 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 KASH_CCD PF14662.4 001314225.1_09023001_3 - 0.011 15.4 3.1 0.024 14.4 0.4 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH JIP_LZII PF16471.3 001314225.1_09023001_3 - 0.018 15.1 0.7 0.018 15.1 0.7 2.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Reo_sigmaC PF04582.10 001314225.1_09023001_3 - 0.033 13.5 0.1 0.051 12.8 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TolA_bind_tri PF16331.3 001314225.1_09023001_3 - 0.051 13.5 2.4 0.088 12.8 0.4 2.4 2 1 0 2 2 2 0 TolA binding protein trimerisation BLOC1_2 PF10046.7 001314225.1_09023001_3 - 0.14 12.3 1.9 6.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Trimer_CC PF08954.9 001314225.1_09023001_3 - 0.2 11.1 0.0 0.2 11.1 0.0 3.4 4 0 0 4 4 4 0 Trimerisation motif PRKG1_interact PF15898.3 001314225.1_09023001_3 - 0.44 11.4 5.3 0.48 11.2 3.6 1.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.9 001314225.1_09023001_3 - 0.47 10.7 2.7 1.4 9.2 0.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Lzipper-MIP1 PF14389.4 001314225.1_09023001_3 - 3.7 7.7 7.1 12 6.1 0.1 3.1 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 CREPT PF16566.3 001319277.1_09022001_3 - 1.7e-62 209.8 5.9 1.7e-62 209.8 5.9 2.0 3 0 0 3 3 3 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.11 001319277.1_09022001_3 - 1.1e-22 80.5 1.3 8.7e-22 77.6 0.0 3.1 4 0 0 4 4 4 1 RNA polymerase II-binding domain. CTK3 PF12243.6 001319277.1_09022001_3 - 0.0033 17.3 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 FemAB PF02388.14 001319277.1_09022001_3 - 0.1 11.4 1.5 0.21 10.3 1.5 1.5 1 0 0 1 1 1 0 FemAB family Rep_4 PF05797.9 001319277.1_09022001_3 - 0.12 11.4 2.2 0.67 8.9 1.9 2.1 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) FimP PF09766.7 001319277.1_09022001_3 - 0.41 9.7 10.3 0.55 9.3 8.5 2.0 1 1 1 2 2 2 0 Fms-interacting protein Atg14 PF10186.7 001319277.1_09022001_3 - 3.1 6.6 8.5 7.4 5.4 8.5 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LIM PF00412.20 001314295.1_09023001_1 - 1.5e-31 108.3 21.3 1.1e-15 57.4 10.1 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.27 001314295.1_09023001_1 - 3.7e-19 68.2 3.4 7.4e-19 67.2 3.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001314295.1_09023001_1 - 8.6e-06 25.4 4.8 9.5e-05 22.1 4.8 2.3 1 1 0 1 1 1 1 Homeobox KN domain DUF1314 PF07013.9 001314295.1_09023001_1 - 0.00056 19.7 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1314) Homez PF11569.6 001314295.1_09023001_1 - 0.0065 15.8 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez TNFR_c6 PF00020.16 001314295.1_09023001_1 - 1 9.7 14.6 10 6.5 0.3 3.5 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region SPAN-X PF07458.10 001042628.1_39721001_1 - 1.9e-42 143.5 7.4 1.9e-42 143.5 7.4 1.6 2 0 0 2 2 2 1 Sperm protein associated with nucleus, mapped to X chromosome MRI PF15325.4 001042628.1_39721001_1 - 5.5 8.1 12.0 10 7.3 3.0 2.2 2 0 0 2 2 2 0 Modulator of retrovirus infection Glyco_transf_29 PF00777.16 001314180.1_09023001_2 - 3.4e-74 249.5 0.0 4.5e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Cornichon PF03311.12 001314180.1_09023001_2 - 0.057 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Cornichon protein DUF2116 PF09889.7 001314180.1_09023001_2 - 0.18 11.7 0.6 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Asp PF00026.21 001285565.1_09023001_1 - 6.4e-103 344.3 0.0 7.4e-103 344.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285565.1_09023001_1 - 2.1e-14 54.1 0.1 1.1e-07 32.2 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001285565.1_09023001_1 - 5.7e-13 48.3 1.9 9.7e-13 47.6 1.9 1.4 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.4 001285565.1_09023001_1 - 0.0055 17.2 0.0 0.23 12.0 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease MAGE PF01454.17 001285645.1_09024001_1 - 8.4e-23 81.0 3.2 7.5e-22 77.9 0.0 2.9 2 1 0 2 2 2 1 MAGE family Interferon PF00143.17 001285704.1_09022001_1 - 8.6e-61 204.7 0.3 9.8e-61 204.5 0.3 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain eIF_4EBP PF05456.9 001285589.1_09021001_1 - 3e-43 146.3 1.5 3.2e-43 146.2 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RhoGAP PF00620.25 001314297.1_09024001_1 - 3.3e-39 134.0 0.0 5.6e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain HLH PF00010.24 001314338.1_09022001_1 - 6.2e-16 58.0 0.1 1.1e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Keratin_B2_2 PF13885.4 001285537.2_09022001_1 - 1.5e-16 59.9 248.1 1.6e+04 -12.5 91.4 6.8 1 1 2 3 3 3 0 Keratin, high sulfur B2 protein Keratin_B2 PF01500.15 001285537.2_09022001_1 - 1.5e-05 24.9 180.8 0.024 14.5 62.9 4.3 1 1 3 4 4 4 4 Keratin, high sulfur B2 protein RSN1_7TM PF02714.13 001314275.1_09025001_1 - 3.4e-56 190.4 21.4 3.4e-56 190.4 21.4 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.4 001314275.1_09025001_1 - 1.7e-44 152.0 0.1 2.5e-44 151.5 0.1 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.4 001314275.1_09025001_1 - 1.1e-21 77.1 2.1 1.1e-21 77.1 2.1 4.5 4 1 1 5 5 5 2 Late exocytosis, associated with Golgi transport RRM_1 PF00076.20 001314275.1_09025001_1 - 8.7e-05 22.1 0.0 0.31 10.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ELO PF01151.16 001314257.1_09026001_1 - 2.5e-67 226.9 26.4 3.7e-67 226.3 26.4 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family NB-ARC PF00931.20 001314175.1_09028001_2 - 7.9e-79 264.5 0.2 1.3e-78 263.8 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain WD40 PF00400.30 001314175.1_09028001_2 - 3.9e-64 210.9 36.0 6.2e-08 33.1 0.2 13.6 13 0 0 13 13 13 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001314175.1_09028001_2 - 1.4e-29 102.0 10.1 5.9e-05 23.2 0.0 9.4 4 4 5 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain CARD PF00619.19 001314175.1_09028001_2 - 2.4e-20 72.2 0.1 7.5e-20 70.6 0.1 2.0 1 0 0 1 1 1 1 Caspase recruitment domain Ge1_WD40 PF16529.3 001314175.1_09028001_2 - 5.6e-13 48.4 10.1 0.026 13.4 0.0 8.1 3 2 5 9 9 9 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.3 001314175.1_09028001_2 - 3.4e-10 39.6 5.5 0.0043 16.3 0.1 5.6 4 2 4 8 8 8 3 WD40-like domain CARD_2 PF16739.3 001314175.1_09028001_2 - 8.5e-08 31.9 0.1 2.9e-07 30.3 0.1 1.9 1 0 0 1 1 1 1 Caspase recruitment domain AAA_16 PF13191.4 001314175.1_09028001_2 - 1.2e-05 25.6 0.0 3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Nbas_N PF15492.4 001314175.1_09028001_2 - 0.0087 15.3 0.1 4.8 6.3 0.0 3.8 4 1 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Hira PF07569.9 001314175.1_09028001_2 - 0.015 14.9 6.1 0.26 10.9 0.0 4.8 4 2 2 6 6 6 0 TUP1-like enhancer of split ATPase_2 PF01637.16 001314175.1_09028001_2 - 0.024 14.4 0.0 0.084 12.6 0.0 2.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.4 001314175.1_09028001_2 - 0.032 14.4 0.0 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.4 001314175.1_09028001_2 - 0.081 13.3 0.0 0.34 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain Forkhead PF00250.16 001314325.1_09025001_2 - 8.5e-30 102.8 0.7 1.4e-29 102.1 0.7 1.3 1 0 0 1 1 1 1 Forkhead domain TRAM_LAG1_CLN8 PF03798.14 001314268.1_09023001_3 - 2.7e-26 92.4 18.8 2.7e-26 92.4 18.8 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.9 001314268.1_09023001_3 - 2.1e-20 72.0 0.9 2.1e-20 72.0 0.9 2.1 2 0 0 2 2 2 1 TRAM1-like protein DUF3671 PF12420.6 001314268.1_09023001_3 - 4.7 7.2 11.5 0.47 10.4 3.7 2.7 2 1 1 3 3 3 0 Protein of unknown function Acetyltransf_1 PF00583.23 001285561.1_09022001_1 - 1.2e-12 47.9 0.0 1.5e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.5 001285561.1_09022001_1 - 3.4e-08 33.4 0.0 4.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 001285561.1_09022001_1 - 3.5e-06 27.2 0.0 5.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain KAAG1 PF15354.4 001285561.1_09022001_2 - 0.93 10.0 9.4 0.68 10.4 2.2 2.6 2 0 0 2 2 2 0 Kidney-associated antigen 1 Keratin_2_head PF16208.3 001285762.1_09022001_2 - 0.019 15.0 18.6 0.029 14.4 18.6 1.2 1 0 0 1 1 1 0 Keratin type II head KRTAP PF11759.6 001285762.1_09022001_2 - 0.043 14.2 78.9 1.6e+04 -7.4 78.9 2.5 1 1 0 1 1 1 0 Keratin-associated matrix SRF-TF PF00319.16 001314231.1_09024001_1 - 5.8e-24 83.2 0.4 1e-23 82.4 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.6 001314231.1_09024001_1 - 1.4e-05 24.9 0.0 1.4e-05 24.9 0.0 2.7 4 0 0 4 4 4 1 Holliday junction regulator protein family C-terminal repeat TFIIA PF03153.11 001314231.1_09024001_1 - 1.1 9.0 5.7 1.4 8.7 5.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 7tm_1 PF00001.19 001314279.1_09025001_1 - 1.1e-29 103.4 21.8 1.7e-29 102.7 21.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.4 001314279.1_09025001_1 - 2.1e-18 65.7 4.2 9.3e-06 25.2 0.3 4.7 3 2 1 4 4 4 4 Leucine rich repeat LRR_5 PF13306.4 001314279.1_09025001_1 - 3.4e-13 49.5 12.8 7.7e-08 32.2 1.9 3.1 1 1 2 3 3 3 2 Leucine rich repeats (6 copies) LRR_4 PF12799.5 001314279.1_09025001_1 - 0.095 13.0 7.5 1.7 9.1 0.2 4.3 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Comm PF15957.3 001314279.1_09025001_1 - 0.12 12.5 0.9 0.32 11.2 0.9 1.7 1 0 0 1 1 1 0 Commissureless zf-C2H2_assoc3 PF16637.3 001171351.1_37925001_1 - 1.8e-33 114.6 5.4 1.8e-33 114.6 5.4 2.2 2 0 0 2 2 1 1 Putative zinc-finger between two C2H2 zinc-fingers on Patz zf-C2H2_4 PF13894.4 001171351.1_37925001_1 - 1.4e-29 100.1 48.2 0.00031 21.2 2.0 8.9 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2 PF00096.24 001171351.1_37925001_1 - 1.1e-26 91.6 55.5 0.00011 22.3 0.7 9.1 9 0 0 9 9 9 7 Zinc finger, C2H2 type BTB PF00651.29 001171351.1_37925001_1 - 6.9e-26 90.5 0.0 1.2e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.4 001171351.1_37925001_1 - 4.5e-14 52.0 57.3 5.6e-06 26.4 2.3 10.1 11 0 0 11 11 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.6 001171351.1_37925001_1 - 5.9e-13 48.6 28.6 0.0039 17.3 0.3 8.8 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001171351.1_37925001_1 - 4.7e-11 42.2 44.1 1e-05 25.2 2.0 8.5 8 0 0 8 8 8 4 C2H2-type zinc finger zf-met PF12874.5 001171351.1_37925001_1 - 7.2e-11 42.0 31.8 0.011 16.0 1.0 8.0 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-Di19 PF05605.10 001171351.1_37925001_1 - 5.1e-05 23.3 27.9 0.11 12.6 1.1 5.9 3 1 3 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.8 001171351.1_37925001_1 - 0.0053 16.7 27.1 0.13 12.3 0.4 5.7 5 1 1 6 6 5 3 Zinc ribbon domain zf-C2H2_2 PF12756.5 001171351.1_37925001_1 - 0.1 12.8 24.6 43 4.4 0.0 7.3 3 1 3 7 7 7 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.9 001171351.1_37925001_1 - 0.11 12.2 19.7 6.3 6.6 0.5 6.1 6 1 1 7 7 7 0 GAGA factor zf-C2H2_8 PF15909.3 001171351.1_37925001_1 - 0.17 12.1 16.1 0.045 13.9 4.8 4.2 3 1 1 4 4 4 0 C2H2-type zinc ribbon DUF629 PF04780.10 001171351.1_37925001_1 - 0.2 10.0 7.8 4.6 5.5 1.1 4.0 3 1 2 5 5 5 0 Protein of unknown function (DUF629) zf-C2H2_9 PF16293.3 001171351.1_37925001_1 - 3.8 7.3 13.2 2.2 8.0 0.0 5.0 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) Endonuclease_7 PF02945.13 001171351.1_37925001_1 - 5.1 7.0 16.8 0.5 10.2 3.6 3.5 1 1 3 4 4 4 0 Recombination endonuclease VII ARS2 PF04959.11 001171351.1_37925001_1 - 7.8 6.7 15.9 0.19 12.0 0.6 4.2 3 2 2 5 5 5 0 Arsenite-resistance protein 2 Asp PF00026.21 001285554.1_09023001_1 - 1.4e-94 316.9 0.0 1.7e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285554.1_09023001_1 - 4.5e-15 56.2 1.5 3.9e-08 33.6 0.1 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001285554.1_09023001_1 - 5.2e-12 45.2 0.9 1.5e-11 43.7 0.9 1.9 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.4 001285554.1_09023001_1 - 0.0014 19.2 0.0 0.16 12.5 0.0 3.2 2 1 1 3 3 3 1 Aspartyl protease Ras PF00071.20 001314182.1_09022001_1 - 3.3e-63 212.0 0.1 4e-63 211.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001314182.1_09022001_1 - 2.1e-33 114.9 0.1 6.2e-33 113.5 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001314182.1_09022001_1 - 2.9e-13 49.5 0.0 3.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001314182.1_09022001_1 - 3.7e-05 23.7 0.0 7.8e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001314182.1_09022001_1 - 0.00017 20.9 0.0 0.00024 20.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001314182.1_09022001_1 - 0.00025 20.5 0.2 0.0012 18.3 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001314182.1_09022001_1 - 0.00041 20.2 0.2 0.25 11.1 0.0 2.4 1 1 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.4 001314182.1_09022001_1 - 0.028 14.5 0.2 0.19 11.8 0.1 2.3 1 1 1 2 2 2 0 AAA domain DAP3 PF10236.7 001314182.1_09022001_1 - 0.067 12.2 0.1 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.4 001314182.1_09022001_1 - 0.099 12.2 0.1 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.25 001314182.1_09022001_1 - 0.32 11.4 1.6 1.3 9.4 1.6 2.1 1 1 0 1 1 1 0 ABC transporter CSD PF00313.20 001314177.1_09022001_1 - 2.3e-16 59.3 0.3 6.9e-16 57.7 0.3 1.8 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.21 001314177.1_09022001_1 - 6.6e-07 29.0 8.7 4.3e-05 23.3 3.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.4 001314177.1_09022001_1 - 0.036 13.6 9.3 0.4 10.3 1.6 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.4 001314177.1_09022001_1 - 0.058 13.1 6.1 1.2 9.0 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle S1 PF00575.21 001314177.1_09022001_1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain CusF_Ec PF11604.6 001314177.1_09022001_1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Homeobox PF00046.27 001314271.1_09023001_2 - 2.6e-18 65.4 5.5 4.6e-18 64.7 5.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.6 001314271.1_09023001_2 - 0.033 13.5 2.5 0.1 12.0 0.6 2.5 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez TFIIF_alpha PF05793.10 001314271.1_09023001_2 - 0.14 10.6 2.5 0.18 10.2 2.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GLTT PF01744.18 001314271.1_09023001_3 - 0.43 10.3 3.1 0.74 9.5 2.1 1.9 1 1 0 1 1 1 0 GLTT repeat (6 copies) CENP-S PF15630.4 001204933.1_37921001_1 - 9.4e-31 105.9 0.3 1.8e-30 105.0 0.3 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.4 001204933.1_37921001_1 - 1.1e-10 41.4 0.5 1.7e-10 40.8 0.5 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.22 001204933.1_37921001_1 - 0.00044 20.5 0.8 0.00044 20.5 0.8 2.0 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.11 001204933.1_37921001_1 - 0.00061 19.6 0.5 0.0086 15.9 0.1 2.1 2 0 0 2 2 2 1 Bromodomain associated COMMD1_N PF17221.1 001204933.1_37921001_1 - 0.016 15.3 1.2 0.028 14.5 1.2 1.5 1 1 0 1 1 1 0 COMMD1 N-terminal domain PID_2 PF14719.4 001314346.1_09022001_1 - 2e-18 66.8 0.2 3.2e-18 66.1 0.2 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.21 001314346.1_09022001_1 - 1.7e-06 28.0 0.2 2.6e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Filament PF00038.19 001285714.1_09024001_1 - 5.9e-92 308.4 21.8 7.7e-92 308.1 21.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein LPP PF04728.11 001285714.1_09024001_1 - 0.6 10.4 3.8 30 5.0 0.0 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper V_ATPase_I PF01496.17 001285714.1_09024001_1 - 3.4 5.3 12.9 0.13 10.0 6.0 1.8 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family FlxA PF14282.4 001285714.1_09024001_1 - 4.1 7.3 19.0 2.7 7.9 12.5 3.4 2 1 1 3 3 3 0 FlxA-like protein Bacillus_HBL PF05791.9 001285714.1_09024001_1 - 8.9 5.9 11.7 0.11 12.1 2.0 2.7 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) TGFb_propeptide PF00688.16 001285646.1_09023001_1 - 1.8e-52 178.4 0.2 2.7e-52 177.8 0.2 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.18 001285646.1_09023001_1 - 5e-34 117.2 0.5 9.4e-34 116.3 0.5 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain Tnp_DNA_bind PF14706.4 001285646.1_09023001_1 - 0.012 15.3 0.1 2.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Transposase DNA-binding Ras PF00071.20 001285599.1_09022001_2 - 6.6e-28 97.2 0.0 8e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001285599.1_09022001_2 - 2.9e-07 30.6 0.0 4.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001285599.1_09022001_2 - 0.00035 19.9 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF2075 PF09848.7 001285599.1_09022001_2 - 0.0023 17.1 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) TMEM173 PF15009.4 001319278.1_09025001_3 - 2.8e-122 407.3 0.0 3.5e-122 407.0 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 173 CIDE-N PF02017.13 001314221.1_09022001_1 - 1.2e-30 105.2 0.1 1.8e-30 104.6 0.1 1.2 1 0 0 1 1 1 1 CIDE-N domain Asp PF00026.21 001285560.1_09023001_1 - 5e-102 341.4 0.0 6.8e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285560.1_09023001_1 - 3.4e-15 56.6 0.8 1.3e-13 51.5 0.8 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001285560.1_09023001_1 - 5.4e-14 51.6 0.8 1.3e-13 50.3 0.8 1.7 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.4 001285560.1_09023001_1 - 0.00049 20.6 0.0 0.18 12.4 0.0 3.4 4 1 0 4 4 4 1 Aspartyl protease gag-asp_proteas PF13975.4 001285560.1_09023001_1 - 0.13 12.7 0.0 3.4 8.2 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SRF-TF PF00319.16 001314200.1_09024001_3 - 1.6e-24 84.9 0.4 2.6e-24 84.3 0.4 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.6 001314200.1_09024001_3 - 5.7e-20 71.0 0.7 5.7e-20 71.0 0.7 3.1 2 1 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat DUF2360 PF10152.7 001314200.1_09024001_3 - 7.4 6.8 8.2 11 6.2 7.1 1.9 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CTF_NFI PF00859.16 001267879.1_39523001_1 - 1e-83 281.6 17.6 1.4e-83 281.1 17.6 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N PF10524.7 001267879.1_39523001_1 - 5.6e-27 93.3 1.7 9.4e-27 92.5 1.7 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.14 001267879.1_39523001_1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 MH1 domain SRF-TF PF00319.16 001314204.1_09023001_1 - 3.7e-24 83.8 0.4 6.6e-24 83.0 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.6 001314204.1_09023001_1 - 3.5e-16 58.8 1.3 5.3e-16 58.2 0.1 2.0 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat F5_F8_type_C PF00754.23 001314312.2_09024001_2 - 5.3e-58 194.5 3.5 9.1e-34 116.2 2.9 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.25 001314312.2_09024001_2 - 3.5e-15 55.9 18.2 2.5e-07 30.7 5.7 2.8 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.5 001314312.2_09024001_2 - 0.00019 21.9 7.5 0.1 13.2 2.4 3.5 2 1 0 2 2 2 2 Human growth factor-like EGF EGF_3 PF12947.5 001314312.2_09024001_2 - 0.0032 17.5 3.5 0.0032 17.5 3.5 2.5 2 0 0 2 2 2 1 EGF domain EGF_2 PF07974.11 001314312.2_09024001_2 - 0.41 10.9 17.5 0.43 10.9 4.5 2.9 2 0 0 2 2 2 0 EGF-like domain EB PF01683.16 001314312.2_09024001_2 - 3.3 7.9 11.2 13 6.0 1.5 2.5 1 1 1 2 2 2 0 EB module Asp PF00026.21 001285568.1_09023001_1 - 2.2e-98 329.4 0.0 2.6e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.4 001285568.1_09023001_1 - 9.6e-15 55.2 0.5 1.2e-07 32.1 0.0 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.10 001285568.1_09023001_1 - 7.4e-13 47.9 2.4 1.4e-12 47.1 2.4 1.5 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.4 001285568.1_09023001_1 - 0.00078 19.9 0.0 0.023 15.3 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.4 001285568.1_09023001_1 - 0.01 15.4 0.0 0.047 13.3 0.0 2.0 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Peptidase_C1_2 PF03051.13 001285568.1_09023001_1 - 0.097 11.3 0.0 0.24 10.0 0.0 1.5 1 1 1 2 2 2 0 Peptidase C1-like family TIMP PF00965.15 001314350.1_09022001_2 - 7.4e-62 208.3 2.3 1.1e-61 207.6 2.3 1.3 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.19 001314350.1_09022001_2 - 0.0024 17.5 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Integrin_beta PF00362.16 001314156.1_09025001_1 - 4.1e-115 383.5 0.0 5.6e-115 383.1 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.9 001314156.1_09025001_1 - 3.8e-23 80.8 0.4 6.9e-23 79.9 0.4 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.10 001314156.1_09025001_1 - 4.9e-22 78.1 9.8 4.9e-22 78.1 9.8 4.5 5 1 1 6 6 6 1 Integrin beta tail domain PSI_integrin PF17205.1 001314156.1_09025001_1 - 3.8e-12 45.7 8.3 3.8e-12 45.7 8.3 4.8 4 1 0 4 4 4 1 Integrin plexin domain EGF_2 PF07974.11 001314156.1_09025001_1 - 1e-08 35.2 58.6 2.4e-06 27.7 13.7 7.3 7 1 1 8 8 8 3 EGF-like domain MHC_II_alpha PF00993.18 001285680.1_09022001_1 - 3.9e-37 125.7 0.0 5.6e-37 125.2 0.0 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001285680.1_09022001_1 - 3.2e-29 100.0 0.6 6.2e-29 99.0 0.6 1.5 1 0 0 1 1 1 1 C1-set C-terminal domain C1-set PF07654.13 001285680.1_09022001_1 - 3.4e-24 85.0 0.0 5.7e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 001285680.1_09022001_1 - 9e-06 26.1 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.13 001285680.1_09022001_1 - 0.00054 19.7 0.0 0.00067 19.4 0.0 1.1 1 0 0 1 1 1 1 Marek's disease glycoprotein A Ig_2 PF13895.4 001285680.1_09022001_1 - 0.00094 19.4 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001285680.1_09022001_1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain C2-set_2 PF08205.10 001285680.1_09022001_1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain SKG6 PF08693.8 001285680.1_09022001_1 - 0.12 11.7 1.9 0.21 10.9 1.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Vert_HS_TF PF06546.9 001314344.2_09024001_2 - 2e-123 411.1 15.6 2e-123 411.1 15.6 2.0 2 0 0 2 2 2 1 Vertebrate heat shock transcription factor HSF_DNA-bind PF00447.15 001314344.2_09024001_2 - 4.7e-33 113.5 0.0 8.5e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2813 PF11398.6 001314344.2_09024001_2 - 0.015 14.5 1.3 0.022 13.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) DUF247 PF03140.13 001314344.2_09024001_2 - 0.015 14.5 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function ZapB PF06005.10 001314344.2_09024001_2 - 0.017 15.4 4.7 0.038 14.3 4.7 1.5 1 0 0 1 1 1 0 Cell division protein ZapB HMMR_C PF15908.3 001314344.2_09024001_2 - 0.41 10.8 7.6 2.9 8.0 0.9 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal COG2 PF06148.9 001314344.2_09024001_2 - 0.77 9.7 3.8 4.9 7.1 0.9 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.11 001314344.2_09024001_2 - 2.4 8.7 5.7 4.8 7.7 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Sugar_tr PF00083.22 001285741.1_09023001_1 - 2.9e-160 533.9 23.9 3.3e-160 533.7 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001285741.1_09023001_1 - 3.8e-20 72.0 31.4 7.6e-20 71.0 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF523 PF04463.10 001285741.1_09023001_1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF523) Phage_holin_3_2 PF04550.10 001285741.1_09023001_1 - 0.16 12.2 6.5 0.45 10.8 4.9 2.5 1 1 1 2 2 2 0 Phage holin family 2 EF1_GNE PF00736.17 001314314.1_09022001_2 - 5.9e-37 125.6 0.5 1e-36 124.8 0.5 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.7 001314314.1_09022001_2 - 9.1e-14 51.5 9.1 2.6e-13 50.0 9.1 1.9 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.4 001314314.1_09022001_2 - 0.015 15.4 0.2 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001314314.1_09022001_2 - 0.035 13.8 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain YL1 PF05764.11 001314314.1_09022001_2 - 0.075 13.0 4.0 0.099 12.6 4.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Troponin PF00992.18 001314190.1_09022001_2 - 6.3e-37 126.7 49.9 2.4e-31 108.7 37.3 3.0 2 1 1 3 3 3 2 Troponin Pkinase PF00069.23 001314202.1_09023001_1 - 6.9e-69 232.0 0.0 8.2e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001314202.1_09023001_1 - 2.8e-35 121.7 0.0 4.1e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001314202.1_09023001_1 - 0.00095 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.18 001314202.1_09023001_1 - 0.06 12.8 0.2 0.094 12.2 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.4 001314202.1_09023001_1 - 0.06 12.8 0.1 0.094 12.2 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.4 001314202.1_09023001_1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.12 001314202.1_09023001_1 - 0.099 11.9 0.3 0.15 11.3 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C1 PF00112.21 001314163.1_09023001_1 - 2e-79 266.6 0.3 3.4e-79 265.9 0.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.10 001314163.1_09023001_1 - 1.6e-19 70.0 4.2 2.7e-19 69.2 4.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.13 001314163.1_09023001_1 - 6.4e-06 25.1 0.9 0.0037 16.0 0.0 2.5 3 0 0 3 3 3 2 Peptidase C1-like family HlyIII PF03006.18 001314307.1_09023001_3 - 2.1e-71 240.1 21.0 2.6e-71 239.8 21.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related EF-hand_7 PF13499.4 001285668.2_09021001_3 - 3.6e-31 107.3 8.6 8.2e-18 64.5 3.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.30 001285668.2_09021001_3 - 1.4e-30 102.4 20.2 2.2e-08 32.9 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.4 001285668.2_09021001_3 - 3.8e-25 87.3 17.2 1.5e-13 50.2 0.5 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.4 001285668.2_09021001_3 - 1.1e-24 84.0 12.8 4.6e-07 29.1 0.2 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.4 001285668.2_09021001_3 - 6.4e-21 72.7 20.1 1e-05 24.6 0.1 4.8 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.4 001285668.2_09021001_3 - 7.3e-17 61.3 0.6 1e-07 32.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.5 001285668.2_09021001_3 - 4.2e-08 32.9 6.2 0.00065 19.5 0.3 3.1 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.7 001285668.2_09021001_3 - 1.2e-06 28.6 0.4 0.00052 20.2 0.3 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.9 001285668.2_09021001_3 - 0.00042 21.0 0.0 0.7 10.7 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain DUF1456 PF07308.11 001285668.2_09021001_3 - 0.00047 20.3 0.9 0.062 13.5 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1456) TerB PF05099.11 001285668.2_09021001_3 - 0.00055 19.8 1.7 0.081 12.7 0.5 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.11 001285668.2_09021001_3 - 0.011 15.6 1.8 7.8 6.3 0.2 3.7 1 1 2 3 3 3 0 Caleosin related protein p25-alpha PF05517.10 001285668.2_09021001_3 - 0.012 15.6 0.3 0.12 12.4 0.1 2.1 1 1 0 2 2 2 0 p25-alpha SurA_N_2 PF13623.4 001285668.2_09021001_3 - 0.031 14.0 0.2 0.079 12.7 0.2 1.6 1 1 1 2 2 2 0 SurA N-terminal domain DUF533 PF04391.10 001285668.2_09021001_3 - 0.037 13.5 2.7 0.048 13.1 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF533) DUF1707 PF08044.9 001285668.2_09021001_3 - 0.044 13.7 2.2 13 5.8 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) FlgD PF03963.12 001285668.2_09021001_3 - 0.094 12.9 0.1 3 8.1 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Pou PF00157.15 001285569.1_09023001_1 - 3.4e-38 129.4 0.8 7.2e-38 128.3 0.8 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001285569.1_09023001_1 - 9.8e-19 66.8 0.5 1.8e-18 66.0 0.5 1.4 1 0 0 1 1 1 1 Homeobox domain DUF521 PF04412.11 001285569.1_09023001_1 - 0.033 12.8 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) APOBEC_N PF08210.9 001305908.1_29724001_3 - 8.1e-86 286.3 4.3 6.2e-46 156.4 0.2 2.1 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001305908.1_29724001_3 - 5.8e-62 205.5 0.0 1e-30 105.3 0.0 2.7 2 0 0 2 2 2 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001305908.1_29724001_3 - 0.0008 19.1 0.0 0.92 9.3 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.4 001305908.1_29724001_3 - 0.0083 16.1 0.5 3.6 7.5 0.3 2.3 2 0 0 2 2 2 2 The BURPS668_1122 family of deaminases Pox_A3L PF05288.9 001305908.1_29724001_3 - 0.16 11.9 0.3 5.3 7.0 0.0 2.8 2 1 0 2 2 2 0 Poxvirus A3L Protein NODP PF07684.10 001305908.1_29724001_3 - 0.53 10.3 4.2 0.82 9.7 1.1 2.2 2 0 0 2 2 2 0 NOTCH protein F-box-like PF12937.5 001171755.1_49823001_3 - 5e-15 55.0 3.5 1.6e-14 53.4 3.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001171755.1_49823001_3 - 9.4e-09 34.8 3.7 4.6e-08 32.6 3.7 2.3 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.31 001171755.1_49823001_3 - 0.027 14.8 17.0 10 6.9 0.3 7.1 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.5 001171755.1_49823001_3 - 0.32 11.4 22.4 1.3 9.3 0.7 5.4 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.4 001171755.1_49823001_3 - 1.8 8.7 18.8 9.1 6.5 0.1 6.7 7 0 0 7 7 7 0 Leucine Rich repeat Skp1 PF01466.17 001144778.1_39521001_1 - 6.9e-31 106.0 1.9 1.3e-30 105.1 1.9 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.13 001144778.1_39521001_1 - 2.1e-30 104.6 0.7 4.5e-30 103.5 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CAP PF00188.24 001285743.1_09023001_2 - 2.6e-24 86.3 4.0 3.6e-24 85.9 4.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Crisp PF08562.8 001285743.1_09023001_2 - 4.1e-20 72.0 19.7 1.1e-19 70.6 19.7 1.8 1 0 0 1 1 1 1 Crisp Ras PF00071.20 001285594.2_09022001_3 - 2.1e-42 144.3 0.0 2.8e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001285594.2_09022001_3 - 3.7e-12 46.4 0.0 6.8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001285594.2_09022001_3 - 3.3e-07 29.8 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001285594.2_09022001_3 - 6.4e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.4 001285594.2_09022001_3 - 0.00011 22.4 0.2 0.083 13.0 0.0 3.0 2 1 1 3 3 3 1 AAA domain DUF258 PF03193.14 001285594.2_09022001_3 - 0.0024 17.7 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.15 001285594.2_09022001_3 - 0.079 12.9 0.7 0.22 11.4 0.1 2.0 3 1 0 3 3 3 0 Domain of unknown function DUF87 FTO_NTD PF12933.5 001104931.1_39524001_2 - 2.4e-117 391.1 0.0 3.7e-117 390.5 0.0 1.3 1 0 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.5 001104931.1_39524001_2 - 1e-64 217.2 5.0 1.9e-64 216.3 5.0 1.5 1 0 0 1 1 1 1 FTO C-terminal domain Tachykinin PF02202.14 001172900.1_09922001_1 - 1.7e-06 27.2 0.3 0.0052 16.4 0.0 2.4 2 0 0 2 2 2 2 Tachykinin family UPF0020 PF01170.16 001170548.1_45724001_3 - 3.5e-55 186.6 0.0 5.3e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.15 001170548.1_45724001_3 - 1e-11 45.0 1.2 3.1e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 THUMP domain Methyltransf_25 PF13649.4 001170548.1_45724001_3 - 6.2e-05 23.5 0.0 0.00017 22.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 001170548.1_45724001_3 - 0.059 13.9 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.12 001170548.1_45724001_3 - 0.077 12.4 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain UPF0020 PF01170.16 001170546.1_45725001_1 - 3.6e-55 186.6 0.0 5.4e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.15 001170546.1_45725001_1 - 1e-11 45.0 1.2 3.1e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 THUMP domain Methyltransf_25 PF13649.4 001170546.1_45725001_1 - 6.4e-05 23.5 0.0 0.00018 22.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 001170546.1_45725001_1 - 0.061 13.8 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.12 001170546.1_45725001_1 - 0.077 12.4 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain FTO_NTD PF12933.5 001199368.1_37925001_3 - 1.7e-120 401.5 0.0 2.2e-120 401.1 0.0 1.2 1 0 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.5 001199368.1_37925001_3 - 8.1e-64 214.3 1.3 1.8e-63 213.1 1.3 1.6 1 0 0 1 1 1 1 FTO C-terminal domain Tachykinin PF02202.14 001172899.1_09923001_1 - 1.8e-06 27.1 0.3 0.0055 16.3 0.0 2.4 2 0 0 2 2 2 2 Tachykinin family FTO_NTD PF12933.5 001319276.1_09024001_2 - 3.2e-117 390.7 0.0 4.8e-117 390.1 0.0 1.3 1 0 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.5 001319276.1_09024001_2 - 1.3e-64 216.9 5.0 2.3e-64 216.0 5.0 1.4 1 0 0 1 1 1 1 FTO C-terminal domain Meis_PKNOX_N PF16493.3 102730.2_32924120_3 - 4e-44 148.7 0.1 7.4e-44 147.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.9 102730.2_32924120_3 - 2.1e-10 40.2 0.3 4.1e-10 39.3 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.27 102730.2_32924120_3 - 0.0053 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain U1snRNP70_N PF12220.6 126538.1_32927120_2 - 7.8e-28 96.8 6.3 1.8e-27 95.7 6.3 1.7 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.20 126538.1_32927120_2 - 1.4e-12 47.1 0.0 2.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.7 126538.1_32927120_3 - 0.013 14.1 34.8 0.02 13.5 34.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AKNA PF12443.6 073134.1_45724120_3 - 7.7e-27 93.7 4.1 1.7e-26 92.6 4.1 1.6 1 0 0 1 1 1 1 AT-hook-containing transcription factor XkdW PF09636.8 073134.1_45724120_3 - 0.061 13.3 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 XkdW protein YtxH PF12732.5 073134.1_45724120_3 - 0.082 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 YtxH-like protein ubiquitin PF00240.21 130128.1_32923120_2 - 0.00016 21.2 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S7e PF01251.16 073161.1_45723120_2 - 1.4e-36 125.9 1.4 2.4e-36 125.1 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S7e Ribosomal_S7e PF01251.16 073161.1_45723120_3 - 9e-10 38.5 0.2 7.5e-08 32.2 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein S7e APOBEC_N PF08210.9 001345940.1_29724001_1 - 2.5e-108 359.6 14.1 3.5e-56 189.8 3.1 2.1 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001345940.1_29724001_1 - 1.4e-63 210.7 1.5 9.7e-32 108.6 0.1 2.5 2 0 0 2 2 2 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001345940.1_29724001_1 - 1.5e-07 31.1 0.1 0.003 17.3 0.1 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.4 001345940.1_29724001_1 - 8.1e-05 22.6 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 2 The BURPS668_1122 family of deaminases Hairy_orange PF07527.11 001345940.1_29724001_1 - 0.002 18.2 0.1 0.93 9.6 0.0 2.4 2 0 0 2 2 2 2 Hairy Orange MafB19-deam PF14437.4 001345940.1_29724001_1 - 0.042 13.5 0.5 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 MafB19-like deaminase APOBEC_N PF08210.9 001305910.1_29723001_1 - 4.8e-107 355.4 12.1 1.9e-57 193.9 2.5 2.0 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001305910.1_29723001_1 - 9.9e-67 220.7 2.6 3.6e-33 113.2 0.1 2.5 2 0 0 2 2 2 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001305910.1_29723001_1 - 1.2e-07 31.4 0.3 0.0099 15.6 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.4 001305910.1_29723001_1 - 2.2e-05 24.4 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 2 The BURPS668_1122 family of deaminases Hairy_orange PF07527.11 001305910.1_29723001_1 - 0.014 15.5 0.1 3.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Hairy Orange Ldh_1_N PF00056.21 001328293.1_39724001_2 - 1.3e-45 154.8 0.1 1.8e-45 154.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.16 001328293.1_39724001_2 - 1.5e-24 86.7 0.0 2.7e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.14 001328293.1_39724001_2 - 0.0017 17.8 0.4 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.12 001328293.1_39724001_2 - 0.04 13.4 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4604 PF15377.4 001242591.2_39724001_1 - 6.3e-26 91.7 11.0 9e-26 91.3 11.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF3047 PF11249.6 001280295.1_39724001_3 - 0.074 12.4 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) DSPc PF00782.18 001246639.1_39725001_1 - 4.1e-07 29.7 0.0 6.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001246639.1_39725001_1 - 3.3e-06 26.7 0.0 4.3e-05 23.1 0.0 1.9 1 1 1 2 2 2 2 Protein-tyrosine phosphatase TPR_1 PF00515.26 001280449.1_39725001_3 - 2.7e-53 175.6 43.3 9.2e-08 31.5 0.3 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.15 001280449.1_39725001_3 - 1.3e-42 140.4 33.7 1.8e-05 24.4 0.2 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.4 001280449.1_39725001_3 - 6.8e-29 99.2 23.3 5.5e-09 35.4 0.1 7.4 5 1 2 7 7 7 6 TPR repeat TPR_8 PF13181.4 001280449.1_39725001_3 - 7.7e-25 84.9 34.0 0.0012 18.8 0.4 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.4 001280449.1_39725001_3 - 4.1e-21 74.9 19.5 5.6e-11 42.4 0.1 7.6 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.4 001280449.1_39725001_3 - 1.2e-18 66.1 0.8 0.37 11.6 0.0 8.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.4 001280449.1_39725001_3 - 2.5e-16 60.0 9.1 0.0024 18.4 0.0 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.4 001280449.1_39725001_3 - 6.3e-16 58.5 17.8 0.0024 18.2 0.2 6.7 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.4 001280449.1_39725001_3 - 6.8e-15 54.2 16.7 0.00081 19.5 0.4 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.4 001280449.1_39725001_3 - 3.1e-13 48.6 17.5 0.024 14.5 0.0 8.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.4 001280449.1_39725001_3 - 9.8e-11 41.5 0.1 0.045 13.8 0.0 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.4 001280449.1_39725001_3 - 7.9e-07 28.6 14.0 0.23 11.3 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat NARP1 PF12569.6 001280449.1_39725001_3 - 2.3e-06 26.7 23.6 0.0082 14.9 0.1 4.9 2 2 3 5 5 5 4 NMDA receptor-regulated protein 1 TPR_6 PF13174.4 001280449.1_39725001_3 - 5.6e-06 26.5 20.3 1.8 9.3 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_3 PF07720.10 001280449.1_39725001_3 - 0.00096 19.0 27.2 0.54 10.2 0.1 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001280449.1_39725001_3 - 0.0015 18.5 25.8 0.02 15.0 0.5 5.4 3 3 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 DnaI_N PF07319.9 001280449.1_39725001_3 - 0.012 16.2 4.1 1.6 9.3 0.2 3.8 2 1 2 4 4 4 0 Primosomal protein DnaI N-terminus Fis1_TPR_C PF14853.4 001280449.1_39725001_3 - 0.012 15.5 22.6 2.2 8.3 0.3 7.6 7 1 1 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.4 001280449.1_39725001_3 - 0.042 14.0 6.8 1 9.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.4 001280449.1_39725001_3 - 0.07 13.5 3.6 1.4 9.3 0.1 3.9 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation MIT PF04212.16 001280449.1_39725001_3 - 0.22 11.5 36.8 0.39 10.7 1.1 8.3 7 1 1 8 8 8 0 MIT (microtubule interacting and transport) domain Wtap PF17098.3 001280449.1_39725001_3 - 0.26 11.1 5.5 0.33 10.8 0.1 2.9 3 0 0 3 3 3 0 WTAP/Mum2p family MAS20 PF02064.13 001280449.1_39725001_3 - 0.74 9.8 5.9 5.9 6.9 0.4 4.1 3 1 2 5 5 4 0 MAS20 protein import receptor BTAD PF03704.15 001280449.1_39725001_3 - 1.7 8.9 5.6 19 5.5 0.0 4.2 3 1 2 5 5 4 0 Bacterial transcriptional activator domain DUF5113 PF17140.2 001280449.1_39725001_3 - 1.8 8.2 13.0 2 8.0 0.2 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF5113) TPR_21 PF09976.7 001280449.1_39725001_3 - 1.9 8.1 15.5 2.1 8.0 0.3 5.3 3 2 2 6 6 6 0 Tetratricopeptide repeat-like domain DHDPS PF00701.20 001246492.1_39724001_3 - 3.3e-48 163.7 0.0 4.1e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peptidase_M42 PF05343.12 001246492.1_39724001_3 - 0.035 13.0 0.3 0.051 12.5 0.3 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase EF-hand_4 PF12763.5 001280217.1_39724001_1 - 4.6e-18 64.9 0.1 2.8e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.3 001280217.1_39724001_1 - 4.8e-17 61.4 1.1 1e-16 60.4 1.1 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.21 001280217.1_39724001_1 - 1.3e-13 51.2 0.0 5.8e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.21 001280217.1_39724001_1 - 6.1e-09 35.8 0.0 1.8e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.30 001280217.1_39724001_1 - 0.00036 19.7 0.1 0.0017 17.6 0.1 2.2 1 0 0 1 1 1 1 EF hand GTP_EFTU PF00009.25 001280217.1_39724001_1 - 0.0018 17.7 0.1 0.062 12.7 0.2 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.11 001280217.1_39724001_1 - 0.0026 17.8 0.1 0.47 10.6 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.10 001280217.1_39724001_1 - 0.0051 16.1 0.0 0.043 13.0 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.16 001280217.1_39724001_1 - 0.012 15.0 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.4 001280217.1_39724001_1 - 0.013 15.7 0.0 0.067 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.4 001280217.1_39724001_1 - 0.056 13.7 0.0 0.38 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.17 001280217.1_39724001_1 - 0.081 12.4 0.0 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.20 001280217.1_39724001_1 - 0.098 12.1 0.1 5.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Ras family AIG1 PF04548.14 001280217.1_39724001_1 - 0.098 11.8 0.0 0.38 9.9 0.0 1.9 2 0 0 2 2 2 0 AIG1 family TsaE PF02367.15 001280217.1_39724001_1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_7 PF13499.4 001280217.1_39724001_1 - 0.1 12.9 0.1 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair DUF4612 PF15389.4 001242610.2_39729001_1 - 8.7e-42 142.6 6.6 1.3e-41 142.1 6.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4612) Glyco_transf_54 PF04666.11 001280339.1_39725001_2 - 3.5e-135 449.4 0.8 5e-135 448.8 0.8 1.2 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF4750 PF15938.3 001280339.1_39725001_2 - 0.11 12.0 0.3 0.25 10.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) Fez1 PF06818.13 001280339.1_39725001_2 - 0.59 10.4 3.2 11 6.3 0.1 2.3 1 1 1 2 2 2 0 Fez1 LIN52 PF10044.7 001280331.1_39725001_2 - 2.8e-28 98.3 0.0 5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Retinal tissue protein BEX PF04538.10 001252003.1_39723001_3 - 3.2e-28 98.7 10.1 4.4e-28 98.3 10.1 1.2 1 0 0 1 1 1 1 Brain expressed X-linked like family Arm PF00514.21 001246411.1_39724001_3 - 4.9e-45 150.1 20.1 7.4e-10 38.4 0.0 9.0 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.20 001246411.1_39724001_3 - 2.4e-15 55.1 7.0 0.015 15.4 0.0 7.2 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.4 001246411.1_39724001_3 - 6.7e-14 51.9 9.2 0.0013 19.0 1.0 5.4 2 2 4 6 6 6 5 HEAT repeats Cnd1 PF12717.5 001246411.1_39724001_3 - 9.2e-14 51.6 5.7 0.0013 18.6 0.2 4.8 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.4 001246411.1_39724001_3 - 1.1e-10 41.6 15.3 0.001 19.4 0.0 6.3 6 1 0 6 6 5 3 HEAT-like repeat DNA_alkylation PF08713.9 001246411.1_39724001_3 - 3e-09 36.8 0.1 0.92 9.0 0.0 4.6 2 1 1 4 4 4 3 DNA alkylation repair enzyme CHASE6_C PF17150.2 001246411.1_39724001_3 - 2.5e-07 31.1 1.5 7.1 7.2 0.0 6.6 7 0 0 7 7 7 1 C-terminal domain of two-partite extracellular sensor domain Atx10homo_assoc PF09759.7 001246411.1_39724001_3 - 2.1e-06 27.6 2.0 1.1 9.3 0.0 5.1 3 2 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.18 001246411.1_39724001_3 - 3.7e-06 25.6 8.4 0.0078 14.7 2.2 3.6 1 1 1 3 3 3 3 Adaptin N terminal region Proteasom_PSMB PF10508.7 001246411.1_39724001_3 - 0.00016 20.2 7.5 0.0028 16.1 0.7 3.3 2 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit NopRA1 PF16201.3 001246411.1_39724001_3 - 0.00065 19.2 0.2 0.47 9.8 0.0 4.1 4 1 1 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 RTP1_C1 PF10363.7 001246411.1_39724001_3 - 0.018 15.1 1.0 0.091 12.8 0.3 2.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3731 PF12531.6 001246411.1_39724001_3 - 0.043 13.5 3.8 12 5.5 0.2 3.3 3 0 0 3 3 3 0 DNA-K related protein V-ATPase_H_C PF11698.6 001246411.1_39724001_3 - 0.05 13.6 4.3 2.3 8.2 0.2 4.0 3 1 2 5 5 5 0 V-ATPase subunit H HEAT_PBS PF03130.14 001246411.1_39724001_3 - 0.064 13.8 13.2 0.35 11.5 0.1 5.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.5 001246411.1_39724001_3 - 0.09 13.2 0.3 3.1 8.3 0.1 3.1 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Rcd1 PF04078.11 001246411.1_39724001_3 - 0.11 11.7 2.4 0.25 10.5 0.2 2.6 3 1 0 3 3 3 0 Cell differentiation family, Rcd1-like RTTN_N PF14726.4 001246411.1_39724001_3 - 0.6 10.9 5.2 2.9 8.7 0.2 3.2 4 1 0 4 4 3 0 Rotatin, an armadillo repeat protein, centriole functioning XPC-binding PF09280.9 001246411.1_39724001_3 - 1.4 8.6 4.7 53 3.5 0.0 5.1 7 0 0 7 7 6 0 XPC-binding domain AP3D1 PF06375.9 001280294.1_39724001_1 - 5.8 7.0 22.7 8.1 6.6 22.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 WD40 PF00400.30 001280294.1_39724001_3 - 1.6e-60 199.5 19.5 9.7e-10 38.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280294.1_39724001_3 - 3e-25 88.2 1.9 0.00012 22.2 0.1 6.2 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 001280294.1_39724001_3 - 4.4e-13 48.6 5.1 0.0028 16.2 0.2 4.5 2 1 3 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.9 001280294.1_39724001_3 - 7.8e-13 48.6 0.1 1.9e-06 27.8 0.0 3.5 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.3 001280294.1_39724001_3 - 1.8e-05 24.1 0.1 0.032 13.4 0.0 3.1 1 1 2 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.3 001280294.1_39724001_3 - 2.6e-05 23.2 4.8 0.23 10.2 0.8 3.8 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.3 001280294.1_39724001_3 - 8.4e-05 21.5 1.4 4.2 6.1 0.0 4.0 1 1 3 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.6 001280294.1_39724001_3 - 0.0021 16.3 0.0 0.05 11.8 0.0 2.2 1 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.9 001280294.1_39724001_3 - 0.18 11.4 1.3 56 3.2 0.0 3.9 3 1 1 4 4 4 0 TUP1-like enhancer of split HECT PF00632.23 001271658.1_39729001_1 - 6.5e-97 324.6 0.4 9.1e-97 324.1 0.4 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.24 001271658.1_39729001_1 - 1.9e-47 158.7 31.1 7.4e-13 48.1 4.2 4.7 4 0 0 4 4 4 4 WW domain Amelogenin PF02948.13 001102460.2_39722001_2 - 2.2e-70 236.7 56.8 2.6e-70 236.4 56.8 1.1 1 0 0 1 1 1 1 Amelogenin Ribophorin_I PF04597.12 001280255.1_39725001_3 - 8.8e-145 483.1 3.5 1.1e-144 482.8 3.5 1.1 1 0 0 1 1 1 1 Ribophorin I CtIP_N PF10482.7 001280255.1_39725001_3 - 0.012 15.5 1.1 0.029 14.3 1.1 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DNA_repr_REX1B PF14966.4 001280255.1_39725001_3 - 0.062 13.8 0.6 0.13 12.8 0.6 1.5 1 0 0 1 1 1 0 DNA repair REX1-B Med15 PF09606.8 001280251.1_39727001_2 - 2.1e-181 605.4 125.9 2.5e-181 605.1 125.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal HipA_N PF07805.10 001280251.1_39727001_2 - 0.38 11.3 2.2 45 4.6 3.1 2.9 2 0 0 2 2 2 0 HipA-like N-terminal domain Lant_dehydr_C PF14028.4 001280251.1_39727001_2 - 2.4 7.5 14.0 31 3.9 14.9 2.3 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term Dickkopf_N PF04706.10 001261842.2_39724001_3 - 4.7e-17 62.1 16.8 4.7e-17 62.1 16.8 3.5 4 1 1 5 5 5 2 Dickkopf N-terminal cysteine-rich region HlyIII PF03006.18 001280306.1_39724001_3 - 2.1e-47 161.6 22.8 3.3e-47 160.9 22.8 1.3 1 0 0 1 1 1 1 Haemolysin-III related Glutaredoxin PF00462.22 001195224.1_39721001_3 - 4.3e-18 65.1 0.1 5.9e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.12 001195224.1_39721001_3 - 4.1e-05 23.8 0.0 5.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.4 001195224.1_39721001_3 - 0.0015 18.7 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.4 001195224.1_39721001_3 - 0.0015 18.8 0.1 0.002 18.4 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.4 001195224.1_39721001_3 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.4 001195224.1_39721001_3 - 0.02 14.6 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.4 001195224.1_39721001_3 - 0.033 14.2 0.1 0.056 13.5 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin Redoxin PF08534.8 001195224.1_39721001_3 - 0.18 11.4 0.3 0.27 10.7 0.2 1.4 1 1 1 2 2 2 0 Redoxin Hormone_1 PF00103.18 001008999.1_39722001_1 - 2.6e-61 207.0 0.9 2.9e-61 206.8 0.9 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Thioredoxin PF00085.18 001246429.1_39725001_1 - 8.6e-66 218.3 0.7 1.8e-33 114.4 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.4 001246429.1_39725001_1 - 2.1e-48 164.6 7.5 1.5e-41 142.3 5.2 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.4 001246429.1_39725001_1 - 3.5e-13 49.8 0.4 6.3e-06 26.5 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.4 001246429.1_39725001_1 - 6.8e-12 45.3 0.0 1e-05 25.5 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.11 001246429.1_39725001_1 - 1.6e-10 40.7 0.1 2.2e-05 23.8 0.0 3.2 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family ERp29_N PF07912.11 001246429.1_39725001_1 - 8.4e-09 35.5 1.4 0.11 12.5 0.0 4.1 4 0 0 4 4 4 3 ERp29, N-terminal domain Thioredoxin_8 PF13905.4 001246429.1_39725001_1 - 1e-08 35.2 0.1 0.017 15.3 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.19 001246429.1_39725001_1 - 1.1e-08 34.8 0.4 0.0025 17.6 0.0 3.7 3 1 0 4 4 4 2 AhpC/TSA family Calsequestrin PF01216.15 001246429.1_39725001_1 - 7.4e-06 25.1 1.4 7.4e-06 25.1 1.4 2.1 1 1 1 2 2 2 1 Calsequestrin Redoxin PF08534.8 001246429.1_39725001_1 - 0.00037 20.0 0.2 0.38 10.3 0.1 2.6 2 0 0 2 2 2 2 Redoxin TraF PF13728.4 001246429.1_39725001_1 - 0.026 14.3 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein HyaE PF07449.9 001246429.1_39725001_1 - 0.052 13.4 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.22 001246429.1_39725001_1 - 0.061 13.4 2.8 2.6 8.2 0.0 3.5 3 1 0 3 3 3 0 Glutaredoxin CREPT PF16566.3 001242586.1_39729001_2 - 1.5e-56 190.5 1.5 2.4e-56 189.9 1.5 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.11 001242586.1_39729001_2 - 2.7e-21 76.0 0.0 6.4e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. WD40 PF00400.30 001246564.1_39724001_1 - 1.3e-28 98.5 12.4 0.00013 22.6 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001246564.1_39724001_1 - 2.2e-16 59.8 0.1 0.0015 18.6 0.0 5.8 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001246564.1_39724001_1 - 4.2e-05 23.4 0.0 0.028 14.2 0.0 2.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.4 001246564.1_39724001_1 - 0.00064 19.2 0.8 0.006 16.1 0.8 2.3 1 1 0 1 1 1 1 PQQ-like domain Ge1_WD40 PF16529.3 001246564.1_39724001_1 - 0.002 17.1 0.1 0.074 11.9 0.0 3.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.3 001246564.1_39724001_1 - 0.0028 16.9 0.0 0.55 9.4 0.0 3.3 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.6 001246564.1_39724001_1 - 0.0049 15.4 0.1 0.54 8.7 0.0 3.2 3 0 0 3 3 3 1 Nucleoporin Nup120/160 DUF5046 PF16465.3 001246564.1_39724001_1 - 0.019 14.3 0.1 0.96 8.7 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) Nbas_N PF15492.4 001246564.1_39724001_1 - 0.078 12.2 0.0 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.4 001246564.1_39724001_1 - 0.13 11.3 0.0 0.5 9.4 0.0 2.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.19 001246564.1_39724001_1 - 2.6 8.0 7.8 28 4.7 0.1 4.6 5 0 0 5 5 5 0 PQQ enzyme repeat Hormone_4 PF00220.15 001243107.1_39722001_1 - 0.14 12.1 0.6 0.42 10.6 0.6 1.8 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain MazG-like PF12643.5 001243107.1_39722001_3 - 1.3e-10 41.3 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 MazG-like family MazG PF03819.15 001243107.1_39722001_3 - 1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain dUTPase_2 PF08761.9 001243107.1_39722001_3 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 1 0 1 1 1 0 dUTPase DNA_pol_B_palm PF14792.4 001280250.1_39725001_1 - 8.2e-35 119.3 0.0 1.7e-34 118.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.4 001280250.1_39725001_1 - 1.4e-21 76.3 0.0 2.8e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.7 001280250.1_39725001_1 - 1.3e-20 72.9 0.1 1.2e-19 69.8 0.1 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.4 001280250.1_39725001_1 - 3.7e-18 65.5 0.1 9.3e-18 64.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.4 001280250.1_39725001_1 - 1.4e-05 25.5 0.1 0.093 13.2 0.0 3.4 3 0 0 3 3 3 2 Helix-hairpin-helix domain BRCT_2 PF16589.3 001280250.1_39725001_1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HHH PF00633.21 001280250.1_39725001_1 - 0.015 15.0 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif NTP_transf_2 PF01909.21 001280250.1_39725001_1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Cdd1 PF11731.6 001280250.1_39725001_1 - 0.024 14.8 0.0 11 6.2 0.0 2.8 2 1 0 2 2 2 0 Pathogenicity locus HHH_2 PF12826.5 001280250.1_39725001_1 - 0.17 11.8 0.0 0.68 9.9 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif BRCT PF00533.24 001280250.1_39725001_1 - 0.18 12.1 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.5 001246658.1_39725001_2 - 1e-27 96.4 6.0 1.8e-11 44.3 0.2 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001246658.1_39725001_2 - 6.9e-24 83.4 5.6 2.4e-08 34.0 0.1 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.4 001246658.1_39725001_2 - 2.6e-23 81.9 9.1 8.2e-07 29.3 0.1 5.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.28 001246658.1_39725001_2 - 3e-23 81.0 6.6 0.0013 19.0 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.4 001246658.1_39725001_2 - 1e-17 62.3 7.3 0.025 15.0 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat zf-H2C2_2 PF13465.4 001099345.1_39729001_1 - 1.3e-110 357.2 132.3 1.2e-08 34.9 0.3 18.9 18 1 0 18 18 18 15 Zinc-finger double domain zf-C2H2 PF00096.24 001099345.1_39729001_1 - 4.8e-59 193.5 140.9 3.4e-06 27.1 0.4 19.0 20 0 0 20 20 20 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001099345.1_39729001_1 - 2.1e-23 80.8 138.7 0.073 13.8 0.7 18.2 19 0 0 19 19 19 14 C2H2-type zinc finger KRAB PF01352.25 001099345.1_39729001_1 - 2.3e-23 81.5 0.3 4e-23 80.7 0.3 1.4 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001099345.1_39729001_1 - 1.2e-07 31.6 90.0 0.099 12.6 1.8 11.6 4 2 10 15 15 15 13 Zinc ribbon domain zf-C2H2_jaz PF12171.6 001099345.1_39729001_1 - 9.1e-07 28.9 78.9 0.25 11.5 0.3 15.2 15 0 0 15 15 15 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001099345.1_39729001_1 - 1.4e-06 27.9 116.0 0.015 15.1 0.6 17.0 17 1 0 17 17 17 10 C2H2-type zinc finger XPA_N PF01286.16 001099345.1_39729001_1 - 0.041 13.8 76.0 1.8 8.5 0.5 16.1 16 0 0 16 16 16 0 XPA protein N-terminal Transposase_22 PF02994.12 001099345.1_39729001_3 - 3.3e-08 32.7 4.9 4.7e-08 32.2 4.9 1.1 1 0 0 1 1 1 1 L1 transposable element HSBP1 PF06825.10 001099345.1_39729001_3 - 0.015 15.1 0.6 0.026 14.3 0.6 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Tmemb_cc2 PF10267.7 001099345.1_39729001_3 - 0.12 11.4 4.5 0.17 10.8 4.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CALCOCO1 PF07888.9 001246386.1_39725001_1 - 9.4e-30 103.6 2.8 9.4e-30 103.6 2.8 2.2 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2126 PF09899.7 001246386.1_39725001_1 - 0.63 7.9 12.2 0.85 7.5 12.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Reo_sigmaC PF04582.10 001246386.1_39725001_1 - 2.1 7.5 13.3 5.3 6.2 2.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.11 001246386.1_39725001_1 - 4 8.0 46.5 9.1 6.8 13.8 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Jnk-SapK_ap_N PF09744.7 001246386.1_39725001_1 - 5.4 7.1 55.3 0.4 10.8 23.1 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TP1 PF02079.14 001246451.1_39721001_2 - 3.3e-31 106.8 20.7 3.3e-31 106.8 20.7 1.8 3 0 0 3 3 3 1 Nuclear transition protein 1 HSD3 PF15244.4 001098548.1_39724001_2 - 6.6e-175 582.5 18.1 6.3e-169 562.8 11.6 2.4 2 1 1 3 3 3 2 Spermatogenesis-associated protein 7, or HSD3 DUF2749 PF10907.6 001280287.1_39726001_1 - 0.76 9.9 3.1 5.4 7.1 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) HMG_box PF00505.17 001280287.1_39726001_2 - 5.4e-23 81.1 2.4 9e-23 80.4 2.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001280287.1_39726001_2 - 1.6e-10 41.3 0.8 3.1e-10 40.4 0.8 1.4 1 0 0 1 1 1 1 HMG-box domain CD225 PF04505.10 001198757.1_39722001_3 - 1.2e-32 111.7 0.8 1.9e-32 111.1 0.8 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Phage_holin_2_3 PF16080.3 001198757.1_39722001_3 - 0.14 11.8 1.5 0.28 10.9 1.5 1.5 1 0 0 1 1 1 0 Bacteriophage holin family HP1 NDK PF00334.17 001279964.1_39724001_1 - 4.7e-77 256.4 0.0 1.6e-38 131.7 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.10 001279964.1_39724001_1 - 4e-05 23.2 0.3 7.7e-05 22.3 0.3 1.5 1 0 0 1 1 1 1 DUF1126 PH-like domain ACT_5 PF13710.4 001279964.1_39724001_1 - 0.00049 19.7 0.1 0.065 12.9 0.0 2.3 2 0 0 2 2 2 2 ACT domain Arg_repressor PF01316.19 001279964.1_39724001_1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Ephrin_rec_like PF07699.11 001280244.1_39727001_2 - 3.1e-07 29.9 68.0 0.0002 20.9 4.8 8.1 4 3 4 8 8 8 7 Putative ephrin-receptor like NCD3G PF07562.12 001280244.1_39727001_2 - 0.00049 19.9 49.5 0.035 14.0 8.3 6.5 5 0 0 5 5 5 3 Nine Cysteines Domain of family 3 GPCR Aldedh PF00171.20 001279820.1_39725001_2 - 2.3e-173 576.9 0.0 3e-173 576.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.9 001279820.1_39725001_2 - 0.12 11.7 0.0 0.95 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) zf-ZPR1 PF03367.11 001280293.1_39724001_2 - 2.1e-110 365.5 0.4 9.7e-57 191.1 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.8 001280293.1_39724001_2 - 0.026 14.5 2.5 15 5.6 0.1 3.5 3 0 0 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.10 001280293.1_39724001_2 - 0.051 13.4 0.3 0.051 13.4 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbons CpXC PF14353.4 001280293.1_39724001_2 - 0.075 12.9 1.2 1.7 8.6 1.1 2.6 2 1 0 2 2 2 0 CpXC protein zf-ribbon_3 PF13248.4 001280293.1_39724001_2 - 0.097 12.0 7.1 4.3 6.7 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.17 001280293.1_39724001_2 - 0.35 10.7 7.0 0.48 10.3 0.7 2.6 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ogr_Delta PF04606.10 001280293.1_39724001_2 - 3.9 7.4 9.1 0.071 13.0 1.4 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DZR PF12773.5 001280293.1_39724001_2 - 6.4 6.7 9.3 1.9 8.5 2.1 3.2 3 1 0 3 3 3 0 Double zinc ribbon VWA_2 PF13519.4 001137557.1_39723001_3 - 1.7e-24 86.4 0.1 1.3e-23 83.6 0.0 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.26 001137557.1_39723001_3 - 2.7e-07 30.9 0.0 7.4e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.12 001137557.1_39723001_3 - 6.6e-07 29.2 0.1 1.1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.18 001137557.1_39723001_3 - 7.9e-07 28.5 10.0 0.00015 21.4 0.4 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif Cpn60_TCP1 PF00118.22 001246572.1_39724001_3 - 4.9e-157 523.4 12.2 5.6e-157 523.2 12.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family 7tm_1 PF00001.19 001302435.1_39724001_2 - 2.8e-72 243.0 12.7 4.6e-72 242.3 12.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001302435.1_39724001_2 - 2.3e-08 33.6 11.3 2.3e-08 33.6 11.3 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001302435.1_39724001_2 - 0.00058 19.1 12.4 0.0016 17.7 12.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.4 001302435.1_39724001_2 - 0.00061 19.5 4.2 0.00061 19.5 4.2 1.6 1 1 0 1 1 1 1 Olfactory receptor Mito_carr PF00153.25 001246385.1_39724001_1 - 2.6e-70 232.3 3.0 5e-24 83.9 0.0 3.5 3 1 1 4 4 4 3 Mitochondrial carrier protein CTNNBL PF08216.9 001246652.1_39724001_1 - 1.7e-41 140.4 0.9 4.6e-41 139.1 0.9 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.21 001246652.1_39724001_1 - 0.00054 19.8 4.6 0.74 9.8 0.2 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.7 001246652.1_39724001_1 - 0.074 13.0 0.1 0.22 11.5 0.1 1.9 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain DASH_Dad4 PF08650.8 001246652.1_39724001_1 - 0.21 11.5 1.2 12 5.8 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad4 DEAD_2 PF06733.13 001246590.1_39725001_1 - 1.1e-47 161.7 0.0 1.8e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.4 001246590.1_39725001_1 - 4.1e-46 157.1 0.1 1.2e-45 155.6 0.1 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.9 001246590.1_39725001_1 - 4.7e-46 156.7 0.1 1.1e-41 142.5 0.0 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.13 001246590.1_39725001_1 - 4.6e-06 26.6 0.0 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.4 001246590.1_39725001_1 - 0.0015 18.7 0.4 0.95 9.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain SesA PF17107.3 001246590.1_39725001_1 - 0.029 14.4 0.3 0.18 11.9 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PhoH PF02562.14 001246590.1_39725001_1 - 0.055 12.8 0.0 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein TIR_2 PF13676.4 001246590.1_39725001_1 - 0.087 13.0 0.1 0.46 10.7 0.0 2.3 2 0 0 2 2 2 0 TIR domain WD40 PF00400.30 001246648.1_39724001_3 - 7.9e-40 134.0 21.3 2.3e-09 37.6 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001246648.1_39724001_3 - 2e-05 24.7 3.3 0.34 11.1 0.1 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.9 001246648.1_39724001_3 - 0.00024 19.9 0.4 0.97 8.0 0.0 3.7 1 1 1 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.4 001246648.1_39724001_3 - 0.0021 17.9 0.0 8.1 6.4 0.0 4.2 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.6 001246648.1_39724001_3 - 0.0036 15.9 4.4 0.47 8.9 0.4 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 HAUS5 PF14817.4 001279926.1_39725001_3 - 3.2e-157 525.0 26.8 1.1e-114 384.4 18.5 2.0 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 5 SLX9 PF15341.4 001279926.1_39725001_3 - 0.0056 17.0 4.4 0.025 14.9 1.5 2.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 RF-1 PF00472.18 001279926.1_39725001_3 - 0.069 13.0 0.0 0.069 13.0 0.0 3.2 2 1 1 3 3 3 0 RF-1 domain DUF342 PF03961.11 001279926.1_39725001_3 - 1.3 7.4 3.4 0.87 8.0 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Fib_alpha PF08702.8 001279926.1_39725001_3 - 4.9 7.2 8.2 1.6e+02 2.3 0.0 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.10 001279926.1_39725001_3 - 5.9 6.8 12.0 0.27 11.1 3.8 2.4 2 0 0 2 2 2 0 Laminin Domain II zf-RING_2 PF13639.4 001280314.1_39724001_2 - 2.4e-12 46.8 6.9 2.4e-12 46.8 6.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.4 001280314.1_39724001_2 - 3.2e-10 39.5 6.2 9.5e-10 38.0 6.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CUE PF02845.14 001280314.1_39724001_2 - 5.9e-10 38.5 0.1 1.1e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 CUE domain zf-RING_UBOX PF13445.4 001280314.1_39724001_2 - 1.3e-08 34.5 2.0 3.1e-08 33.3 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001280314.1_39724001_2 - 4.2e-08 32.8 4.9 9.5e-08 31.7 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001280314.1_39724001_2 - 2.3e-07 30.5 3.2 6.3e-07 29.0 3.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.3 001280314.1_39724001_2 - 6.7e-07 28.8 1.4 6.7e-07 28.8 1.4 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.5 001280314.1_39724001_2 - 1.7e-06 28.1 10.7 5.9e-06 26.3 8.5 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.4 001280314.1_39724001_2 - 1e-05 25.1 4.2 2.5e-05 23.9 4.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 001280314.1_39724001_2 - 1.7e-05 24.6 3.4 3.8e-05 23.4 3.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.5 001280314.1_39724001_2 - 2.8e-05 23.9 0.5 8.1e-05 22.5 0.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.3 001280314.1_39724001_2 - 4.6e-05 22.8 4.8 0.00012 21.5 4.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.4 001280314.1_39724001_2 - 0.0024 17.9 4.1 0.0052 16.8 4.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.6 001280314.1_39724001_2 - 0.6 10.2 5.3 1.8 8.7 5.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain UbiA PF01040.16 001280314.1_39724001_2 - 2.6 7.2 11.3 0.92 8.6 8.7 1.5 2 0 0 2 2 2 0 UbiA prenyltransferase family Glyco_transf_29 PF00777.16 001193678.1_39722001_1 - 1.2e-36 126.4 0.0 1.8e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Myb_DNA-bind_5 PF13873.4 001246522.1_39724001_3 - 2.4e-24 85.1 2.0 4.5e-24 84.2 2.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.7 001246522.1_39724001_3 - 0.0036 17.4 0.4 0.0094 16.1 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_S68 PF10461.7 001246522.1_39724001_3 - 0.11 12.5 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Peptidase S68 Syja_N PF02383.16 001114624.1_39727001_1 - 2.3e-71 240.5 0.0 3.8e-71 239.8 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Cluap1 PF10234.7 001280352.1_39724001_1 - 1.9e-114 381.5 13.2 2.7e-114 381.0 13.2 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 SseC PF04888.10 001280352.1_39724001_1 - 0.0058 16.0 3.8 0.008 15.6 3.8 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family TFIIA PF03153.11 001280352.1_39724001_1 - 0.13 12.1 11.3 0.16 11.8 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SesA PF17107.3 001280352.1_39724001_1 - 0.18 11.9 7.9 2.4 8.2 2.0 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RasGAP_C PF03836.13 001280352.1_39724001_1 - 0.24 11.4 12.6 0.55 10.2 12.6 1.6 1 0 0 1 1 1 0 RasGAP C-terminus OmpH PF03938.12 001280352.1_39724001_1 - 6.8 6.5 22.3 20 5.1 20.2 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Ipi1_N PF12333.6 001280494.1_39727001_3 - 1.6e-20 73.4 0.5 1.6e-20 73.4 0.5 4.0 5 1 1 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.5 001280494.1_39727001_3 - 0.018 15.5 0.0 0.1 13.0 0.0 2.3 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT PF02985.20 001280494.1_39727001_3 - 0.071 13.2 0.1 0.76 10.0 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.4 001280494.1_39727001_3 - 0.11 12.7 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats M11L PF11099.6 001280494.1_39727001_3 - 1.2 9.3 3.8 0.55 10.4 0.1 2.2 2 0 0 2 2 2 0 Apoptosis regulator M11L like TBP PF00352.19 001104607.1_39724001_2 - 6.8e-65 214.9 0.2 2.6e-31 107.3 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 PF10513.7 001104607.1_39724001_2 - 0.00018 21.8 6.9 0.00024 21.4 6.9 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like DDHD PF02862.15 001104607.1_39724001_2 - 0.00087 19.4 3.8 0.0011 19.0 3.8 1.2 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.15 001104607.1_39724001_2 - 0.002 16.8 9.8 0.0043 15.7 9.8 1.5 1 0 0 1 1 1 1 Presenilin Spt20 PF12090.6 001104607.1_39724001_2 - 0.0031 17.0 41.0 0.0048 16.4 41.0 1.2 1 0 0 1 1 1 1 Spt20 family TMEM51 PF15345.4 001104607.1_39724001_2 - 0.011 15.5 8.7 0.016 14.9 8.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4746 PF15928.3 001104607.1_39724001_2 - 0.013 14.9 2.3 0.017 14.4 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.11 001104607.1_39724001_2 - 0.028 14.3 37.9 0.038 13.9 37.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.8 001104607.1_39724001_2 - 0.067 13.3 12.2 0.096 12.8 12.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SpoIIP PF07454.9 001104607.1_39724001_2 - 0.073 12.4 11.6 0.11 11.9 11.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ABC2_membrane_2 PF12679.5 001104607.1_39724001_2 - 0.091 11.9 0.8 0.13 11.4 0.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PAT1 PF09770.7 001104607.1_39724001_2 - 0.46 8.6 27.5 0.61 8.2 27.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.14 001104607.1_39724001_2 - 0.56 10.1 7.9 0.82 9.5 7.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.6 001104607.1_39724001_2 - 0.66 9.7 3.3 1.1 9.0 3.3 1.3 1 0 0 1 1 1 0 N-glycosylation protein Lin-8 PF03353.13 001104607.1_39724001_2 - 1.3 8.4 16.6 1.9 7.9 16.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Tim54 PF11711.6 001104607.1_39724001_2 - 1.7 7.2 14.6 2.6 6.6 14.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FemAB PF02388.14 001104607.1_39724001_2 - 2 7.1 13.2 2.8 6.6 13.2 1.1 1 0 0 1 1 1 0 FemAB family DUF106 PF01956.14 001104607.1_39724001_2 - 2.3 7.8 8.6 4.8 6.8 8.6 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF1980 PF09323.8 001104607.1_39724001_2 - 2.5 7.9 7.5 3.8 7.2 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) GREB1 PF15782.3 001104607.1_39724001_2 - 3.3 4.6 15.6 4.6 4.1 15.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.8 001104607.1_39724001_2 - 3.5 6.1 15.8 4.8 5.6 15.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.6 001104607.1_39724001_2 - 6.2 5.4 11.9 8.8 4.9 11.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TERB2 PF15101.4 001104607.1_39724001_2 - 8.6 6.2 23.1 15 5.5 23.1 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 VID27 PF08553.8 001104607.1_39724001_2 - 9.1 4.5 15.1 12 4.1 15.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein PIH1 PF08190.10 001104607.1_39724001_2 - 9.3 5.9 22.2 14 5.2 22.2 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CPSF100_C PF13299.4 001104607.1_39724001_2 - 9.8 6.2 14.4 19 5.3 14.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF1645 PF07816.9 001104607.1_39724001_3 - 0.053 14.0 14.0 0.092 13.2 14.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) PI3K_1B_p101 PF10486.7 001104607.1_39724001_3 - 1.1 6.8 6.8 1.4 6.4 6.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SR-25 PF10500.7 001104607.1_39724001_3 - 2.7 7.4 29.0 5.5 6.4 29.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF775 PF05603.10 001242569.1_39723001_1 - 1.8e-56 190.7 0.3 2.6e-56 190.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Chitin_bind_1 PF00187.17 001242569.1_39723001_3 - 0.69 10.3 11.9 2.6 8.5 11.9 2.0 1 0 0 1 1 1 0 Chitin recognition protein LURAP PF14854.4 001244663.2_39723001_3 - 0.00044 20.0 0.0 0.00088 19.1 0.0 1.4 1 0 0 1 1 1 1 Leucine rich adaptor protein IQ PF00612.25 001246476.1_39724001_3 - 0.0027 17.2 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dpy-30 PF05186.11 001246476.1_39724001_3 - 0.027 14.0 0.1 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Dpy-30 motif Cyclin_N PF00134.21 001246437.1_39724001_1 - 4.7e-48 162.0 0.2 8.5e-48 161.2 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001246437.1_39724001_1 - 8.5e-29 99.9 1.0 3.3e-28 98.0 0.2 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain dsrm PF00035.24 001280270.1_39724001_1 - 0.008 16.7 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.24 001280270.1_39724001_1 - 0.1 13.1 0.0 1 9.9 0.0 2.3 1 1 0 1 1 1 0 Ribonuclease III domain FGGY_N PF00370.19 001246376.1_39724001_1 - 2e-90 302.5 0.0 2.7e-90 302.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.14 001246376.1_39724001_1 - 5.1e-64 215.5 0.3 1.1e-63 214.4 0.1 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Ald_Xan_dh_C2 PF02738.16 001308443.1_39729001_2 - 1.8e-187 624.0 0.0 2.3e-187 623.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.19 001308443.1_39729001_2 - 2.7e-44 150.8 0.0 5.5e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.20 001308443.1_39729001_2 - 5.5e-33 113.5 0.1 1e-32 112.6 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.18 001308443.1_39729001_2 - 9.5e-31 105.4 0.8 2.4e-30 104.2 0.8 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.15 001308443.1_39729001_2 - 1e-27 96.1 0.0 2.7e-27 94.8 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.25 001308443.1_39729001_2 - 1.9e-08 34.0 3.5 3.3e-08 33.2 0.1 2.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain MHC_II_beta PF00969.17 001271071.1_39723001_2 - 4.1e-36 122.8 1.2 6.3e-36 122.2 1.2 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 001271071.1_39723001_2 - 9.3e-25 86.8 0.1 1.6e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.23 001271071.1_39723001_2 - 0.0016 18.4 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain MHC_I PF00129.16 001271071.1_39723001_2 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 HCBP_related PF06594.9 001279825.1_39724001_1 - 0.036 13.9 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain DUF788 PF05620.9 001279825.1_39724001_1 - 0.14 11.9 1.1 0.21 11.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) CAF1 PF04857.18 001279825.1_39724001_3 - 8.7e-80 268.1 0.0 2.3e-79 266.8 0.0 1.6 2 0 0 2 2 2 1 CAF1 family ribonuclease Reprolysin PF01421.17 001328305.1_39726001_1 - 4.9e-51 173.3 0.1 4.9e-51 173.3 0.1 2.1 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.10 001328305.1_39726001_1 - 1.8e-31 108.8 8.7 1.8e-31 108.8 8.7 3.6 3 2 0 3 3 3 1 ADAM cysteine-rich Disintegrin PF00200.21 001328305.1_39726001_1 - 5.3e-20 71.9 24.0 5.3e-20 71.9 24.0 3.8 3 0 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.17 001328305.1_39726001_1 - 1.8e-19 70.2 0.0 3.5e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.4 001328305.1_39726001_1 - 6.3e-15 55.7 1.1 1.3e-14 54.7 1.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.4 001328305.1_39726001_1 - 2.6e-12 47.2 0.1 5.4e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.4 001328305.1_39726001_1 - 7e-09 35.5 0.2 1.1e-08 34.8 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.4 001328305.1_39726001_1 - 2.3e-07 30.8 0.2 5.8e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ASF1_hist_chap PF04729.11 001289426.1_39724001_3 - 1.3e-68 229.7 0.0 1.6e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone tRNA-synt_1d PF00750.17 001246569.1_39725001_2 - 3e-170 565.6 0.2 4.5e-170 565.1 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.13 001246569.1_39725001_2 - 1.3e-32 112.4 0.1 3.9e-32 110.8 0.1 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.14 001246569.1_39725001_2 - 3e-24 85.3 0.1 7.6e-24 84.0 0.1 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.17 001246569.1_39725001_2 - 0.00034 19.9 0.2 0.0023 17.2 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Mto2_bdg PF12808.5 001246569.1_39725001_2 - 8 6.7 12.9 7.7 6.8 2.1 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TIR PF01582.18 001130464.1_39725001_1 - 2.5e-23 82.6 0.3 4.6e-23 81.8 0.3 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001130464.1_39725001_1 - 6.2e-22 77.0 46.2 1.9e-12 46.6 4.2 6.9 4 2 2 7 7 7 5 Leucine rich repeat LRR_4 PF12799.5 001130464.1_39725001_1 - 5.3e-16 58.3 46.8 1.9e-06 27.9 0.4 8.5 4 3 6 10 10 10 9 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001130464.1_39725001_1 - 2.3e-07 31.0 0.0 4.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001130464.1_39725001_1 - 5.4e-07 29.0 40.3 1.4 9.5 0.1 12.3 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.4 001130464.1_39725001_1 - 1.5e-05 24.6 30.7 3.9 7.7 0.0 10.7 11 0 0 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.4 001130464.1_39725001_1 - 0.00066 19.1 12.7 0.63 9.4 1.7 3.6 2 1 2 4 4 4 3 Leucine-rich repeat LRRCT PF01463.22 001130464.1_39725001_1 - 0.00079 19.7 0.2 0.0085 16.4 0.0 2.8 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain RabGAP-TBC PF00566.16 001280272.1_39725001_2 - 7.1e-36 123.8 0.0 9.6e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain G-patch PF01585.21 001280507.1_39726001_1 - 1.3e-12 47.3 1.4 2.4e-12 46.4 1.4 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.20 001280507.1_39726001_1 - 2.5e-05 23.9 0.1 4.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Latrophilin PF02354.14 001190486.2_39729001_1 - 1.1e-135 452.4 21.4 7.1e-102 341.1 7.0 2.2 1 1 1 2 2 2 2 Latrophilin Cytoplasmic C-terminal region OLF PF02191.14 001190486.2_39729001_1 - 3.6e-83 278.8 6.0 6.2e-83 278.0 6.0 1.4 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_2 PF00002.22 001190486.2_39729001_1 - 5.2e-68 228.8 23.0 8.2e-68 228.2 23.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.3 001190486.2_39729001_1 - 2.4e-55 187.1 0.8 3.5e-55 186.6 0.8 1.2 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.16 001190486.2_39729001_1 - 8e-24 83.7 0.6 2.1e-23 82.4 0.6 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain GPS PF01825.19 001190486.2_39729001_1 - 1.1e-13 51.4 4.7 4.1e-13 49.6 4.7 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.20 001190486.2_39729001_1 - 1.3e-08 34.9 1.2 3.1e-08 33.6 1.2 1.7 1 0 0 1 1 1 1 Hormone receptor domain zf-C2HCIx2C PF10782.7 001190486.2_39729001_1 - 1.2 9.0 5.0 3.4 7.5 5.0 1.8 1 0 0 1 1 1 0 Zinc-finger DUF5074 PF16819.3 001190486.2_39729001_1 - 1.3 9.0 6.4 0.93 9.4 1.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5074) 7tm_4 PF13853.4 001243969.1_39722001_1 - 1.2e-51 176.0 13.0 1.4e-51 175.7 13.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001243969.1_39722001_1 - 9.3e-27 93.8 10.9 1.5e-26 93.1 10.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001243969.1_39722001_1 - 1.9e-09 37.1 5.5 1.9e-09 37.1 5.5 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001243969.1_39722001_1 - 0.0097 15.1 5.1 0.017 14.3 5.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Adeno_E3_15_3 PF03307.12 001243969.1_39722001_1 - 0.03 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region DUF825 PF05695.10 001243969.1_39722001_1 - 0.22 8.5 0.2 0.28 8.2 0.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Lectin_C PF00059.19 001130473.1_39722001_1 - 6.2e-22 78.3 5.4 1e-21 77.5 5.4 1.4 1 0 0 1 1 1 1 Lectin C-type domain BRICHOS PF04089.12 001130473.1_39722001_1 - 0.068 13.1 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 BRICHOS domain Tti2 PF10521.7 001246539.1_39724001_3 - 1.7e-15 57.2 6.0 6.8e-14 51.9 5.1 2.7 1 1 1 2 2 2 1 Tti2 family F-box PF00646.31 001246539.1_39724001_3 - 0.12 12.1 1.2 1.1 9.1 0.2 2.7 2 0 0 2 2 2 0 F-box domain DUF2615 PF11027.6 001246570.1_39724001_2 - 1.9e-36 124.3 0.0 4.5e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) DUF1467 PF07330.10 001246457.1_39725001_2 - 0.11 12.3 1.6 0.2 11.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) Ras PF00071.20 001246457.1_39725001_3 - 4.8e-62 208.2 0.1 7e-62 207.7 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001246457.1_39725001_3 - 3.6e-32 111.0 0.0 6.9e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001246457.1_39725001_3 - 3.6e-12 46.0 0.0 5.4e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001246457.1_39725001_3 - 0.00043 20.2 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.10 001246457.1_39725001_3 - 0.0023 17.2 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001246457.1_39725001_3 - 0.0057 16.1 0.1 0.017 14.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001246457.1_39725001_3 - 0.012 15.4 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SH3BGR PF04908.13 001246405.2_39724001_1 - 3.8e-45 152.0 0.0 5.2e-45 151.5 0.0 1.2 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.22 001246405.2_39724001_1 - 0.0049 16.9 0.0 0.0087 16.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin 7tm_1 PF00001.19 001246635.1_39725001_3 - 3.8e-33 114.7 16.2 5.2e-33 114.3 16.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001246635.1_39725001_3 - 0.11 11.7 8.1 0.16 11.2 8.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv PRP3 PF08572.8 001246426.1_39725001_3 - 1.4e-79 266.8 7.4 1.4e-79 266.8 7.4 2.7 3 1 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.10 001246426.1_39725001_3 - 1.2e-48 164.7 1.9 3.7e-48 163.2 1.9 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PWI PF01480.15 001246426.1_39725001_3 - 1.6e-13 50.6 0.0 4e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 PWI domain B PF02216.14 001246426.1_39725001_3 - 0.18 11.7 0.6 6.2 6.8 0.1 2.6 2 0 0 2 2 2 0 B domain Methyltransf_32 PF13679.4 001246426.1_39725001_3 - 6 6.7 7.2 14 5.5 3.9 3.1 2 1 0 2 2 2 0 Methyltransferase domain Ank_5 PF13857.4 001280369.1_39726001_1 - 1.9e-07 31.1 0.2 2e-06 27.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.5 001280369.1_39726001_1 - 3.4e-06 27.4 0.0 7.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.4 001280369.1_39726001_1 - 2.3e-05 24.3 0.3 0.0013 18.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.28 001280369.1_39726001_1 - 3.5e-05 23.9 0.4 0.00017 21.8 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.4 001280369.1_39726001_1 - 6.1e-05 23.4 0.0 0.0085 16.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) zf-FCS PF06467.12 001280369.1_39726001_1 - 8.2 6.4 11.7 29 4.6 4.3 3.9 3 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Ank_2 PF12796.5 001280033.1_39724001_1 - 2.6e-51 172.0 5.1 3.5e-16 59.4 0.1 4.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001280033.1_39724001_1 - 2e-46 155.7 18.1 6.5e-10 39.2 0.5 6.4 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.4 001280033.1_39724001_1 - 4.9e-32 109.3 6.8 1e-08 35.1 0.0 6.2 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.28 001280033.1_39724001_1 - 2e-30 103.7 11.5 2.3e-06 27.7 0.2 8.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.4 001280033.1_39724001_1 - 6.5e-26 87.4 5.4 0.00032 20.8 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat HalX PF08663.8 001280033.1_39724001_1 - 0.0044 17.1 6.8 0.01 16.0 6.8 1.6 1 0 0 1 1 1 1 HalX domain DUF641 PF04859.10 001280033.1_39724001_1 - 0.01 16.1 3.8 0.022 14.9 3.8 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) DUF1843 PF08898.8 001280033.1_39724001_1 - 0.052 13.9 3.2 18 5.8 0.0 4.6 5 1 1 6 6 6 0 Domain of unknown function (DUF1843) AAA_23 PF13476.4 001280033.1_39724001_1 - 1 9.7 7.9 2.2 8.6 7.9 1.6 1 0 0 1 1 1 0 AAA domain Transket_pyr PF02779.22 001279904.1_39726001_3 - 1.4e-36 125.7 0.1 2.9e-36 124.7 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 001279904.1_39726001_3 - 4.5e-30 104.0 0.6 1.1e-29 102.7 0.6 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.19 001279904.1_39726001_3 - 2.8e-28 98.7 0.0 1.6e-21 76.5 0.0 2.5 2 1 1 3 3 3 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.18 001279904.1_39726001_3 - 2.5e-07 29.8 0.0 3.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.4 001279904.1_39726001_3 - 0.054 12.6 0.0 0.85 8.6 0.0 2.5 2 1 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase Arm PF00514.21 001280059.1_39726001_2 - 4e-43 144.1 11.3 6.6e-06 25.9 0.0 10.5 10 0 0 10 10 10 7 Armadillo/beta-catenin-like repeat EDR1 PF14381.4 001280059.1_39726001_2 - 2e-37 128.8 0.0 5.4e-37 127.4 0.0 1.7 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.4 001280059.1_39726001_2 - 2.4e-26 91.8 7.7 9.8e-07 28.9 0.1 6.7 2 1 5 7 7 7 7 HEAT repeats HEAT PF02985.20 001280059.1_39726001_2 - 1.4e-17 62.1 10.0 0.087 13.0 0.0 9.1 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.4 001280059.1_39726001_2 - 8.2e-16 58.0 6.5 0.25 11.7 0.0 8.1 8 1 1 9 9 9 4 HEAT-like repeat V-ATPase_H_C PF11698.6 001280059.1_39726001_2 - 5.5e-09 36.0 10.0 0.34 10.9 0.0 6.4 2 2 6 8 8 8 3 V-ATPase subunit H Cnd1 PF12717.5 001280059.1_39726001_2 - 2.4e-08 34.0 13.0 0.051 13.4 0.2 5.1 2 2 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.12 001280059.1_39726001_2 - 5.1e-07 29.1 2.2 0.0053 16.0 0.0 3.5 1 1 1 2 2 2 2 V-ATPase subunit H UNC45-central PF11701.6 001280059.1_39726001_2 - 5.2e-07 29.6 5.4 0.004 17.0 0.1 4.0 2 1 2 4 4 4 3 Myosin-binding striated muscle assembly central CLASP_N PF12348.6 001280059.1_39726001_2 - 0.0012 18.4 1.8 0.24 10.8 0.0 3.5 2 1 0 3 3 3 1 CLASP N terminal Arm_2 PF04826.11 001280059.1_39726001_2 - 0.0021 17.4 11.7 0.036 13.4 1.2 4.1 1 1 3 4 4 4 1 Armadillo-like MOR2-PAG1_C PF14225.4 001280059.1_39726001_2 - 0.071 12.8 0.4 0.35 10.5 0.0 2.1 1 1 1 2 2 2 0 Cell morphogenesis C-terminal RasGEF_N_2 PF14663.4 001280059.1_39726001_2 - 0.49 10.6 7.0 14 5.9 0.1 5.2 5 2 2 7 7 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_PBS PF03130.14 001280059.1_39726001_2 - 3.7 8.4 9.2 18 6.2 0.7 5.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat KBP_C PF12309.6 001280409.1_39726001_1 - 1.1e-120 403.3 5.5 1.1e-120 403.3 5.5 2.4 2 1 0 2 2 2 1 KIF-1 binding protein C terminal TPR_12 PF13424.4 001280409.1_39726001_1 - 0.0043 17.2 8.0 0.22 11.7 1.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.26 001280409.1_39726001_1 - 0.16 11.7 9.1 0.13 12.0 0.8 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.4 001280409.1_39726001_1 - 3.9 7.6 10.3 1.5 8.9 0.5 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.5 001246431.2_39724001_3 - 2.3e-10 40.5 0.2 0.082 13.1 0.0 6.1 3 3 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.30 001246431.2_39724001_3 - 6.8e-06 26.6 9.6 0.00022 21.8 0.1 5.2 6 0 0 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.10 001246431.2_39724001_3 - 0.0009 19.0 1.4 0.59 10.0 0.1 3.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ras PF00071.20 001279916.1_39724001_2 - 6.2e-25 87.5 0.1 7.7e-25 87.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001279916.1_39724001_2 - 2.9e-10 40.3 0.0 5.3e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001279916.1_39724001_2 - 4.2e-07 29.5 0.0 5.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001279916.1_39724001_2 - 0.00016 21.6 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001279916.1_39724001_2 - 0.00032 20.2 0.2 0.035 13.5 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.21 001279916.1_39724001_2 - 0.0015 18.5 0.2 0.0038 17.2 0.2 1.6 1 1 0 1 1 1 1 Dynamin family DUF258 PF03193.14 001279916.1_39724001_2 - 0.033 14.0 0.2 2.7 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF2121 PF09894.7 001279916.1_39724001_2 - 0.044 13.2 0.1 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) RNA_pol_Rpb4 PF03874.14 001251959.2_39725001_2 - 8.5e-24 84.1 6.0 1.2e-23 83.6 6.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ribosomal_S26e PF01283.17 001251959.2_39725001_2 - 5.7e-17 62.0 0.5 1.1e-16 61.1 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S26e Tfb4 PF03850.12 001251959.2_39725001_2 - 0.091 12.0 1.0 0.11 11.8 0.1 1.4 2 0 0 2 2 2 0 Transcription factor Tfb4 DEAD PF00270.27 001280484.1_39725001_3 - 5.9e-44 149.8 0.0 2.6e-43 147.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001280484.1_39725001_3 - 1.3e-31 109.1 0.0 9.4e-30 103.1 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-CCHC PF00098.21 001280484.1_39725001_3 - 0.0014 18.5 1.5 0.0028 17.5 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle ResIII PF04851.13 001280484.1_39725001_3 - 0.028 14.3 0.0 0.071 13.0 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.12 001280484.1_39725001_3 - 0.095 11.8 0.0 0.28 10.3 0.0 1.8 2 1 0 2 2 2 0 SecA DEAD-like domain zf-CCHC_4 PF14392.4 001280484.1_39725001_3 - 0.14 11.7 1.3 0.3 10.7 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle ERCC3_RAD25_C PF16203.3 001280484.1_39725001_3 - 0.23 10.5 0.0 0.23 10.5 0.0 1.8 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.4 001280484.1_39725001_3 - 0.47 9.6 2.3 0.79 8.9 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ig PF00047.23 001105154.1_39723001_1 - 7.4e-30 102.8 0.0 2.5e-10 40.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001105154.1_39723001_1 - 5.8e-18 64.9 0.1 3.4e-08 33.6 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001105154.1_39723001_1 - 9e-16 58.1 0.0 0.00011 22.6 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001105154.1_39723001_1 - 9.5e-08 32.0 0.0 1.6 8.8 0.0 5.2 5 1 1 6 6 6 3 Immunoglobulin V-set domain VHS PF00790.17 001280281.1_39724001_1 - 5.9e-43 146.0 1.4 1.4e-42 144.8 0.1 2.3 3 0 0 3 3 3 1 VHS domain SH3_1 PF00018.26 001280281.1_39724001_1 - 2e-18 65.5 0.1 4.1e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.15 001280281.1_39724001_1 - 1.5e-11 43.6 0.0 2.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.4 001280281.1_39724001_1 - 3e-11 42.9 0.0 6.1e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.18 001280281.1_39724001_1 - 4.4e-05 23.0 2.6 0.0001 21.8 2.6 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif ENTH PF01417.18 001280281.1_39724001_1 - 0.07 13.0 0.0 0.19 11.7 0.0 1.9 1 1 0 1 1 1 0 ENTH domain GAT PF03127.12 001280281.1_39724001_1 - 0.19 11.9 1.8 0.41 10.9 1.8 1.6 1 0 0 1 1 1 0 GAT domain DUF2367 PF10164.7 001252551.1_39722001_1 - 1.6e-33 115.1 4.3 3e-33 114.3 4.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) SHMT PF00464.17 001280175.1_39725001_3 - 3.1e-211 701.0 0.0 3.7e-211 700.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.19 001280175.1_39725001_3 - 0.00033 19.8 0.0 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II ARA70 PF12489.6 001280302.1_39725001_3 - 1.3e-74 248.6 33.7 2.9e-47 160.0 5.9 5.9 3 2 1 4 4 4 3 Nuclear coactivator NTP_transf_7 PF07984.10 001246587.1_39725001_1 - 2.1e-158 526.5 0.4 2.5e-158 526.3 0.4 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase Macro PF01661.19 001242422.1_39726001_1 - 4.1e-28 97.6 0.0 6.9e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.3 001242422.1_39726001_1 - 4.8e-18 64.5 1.4 1.5e-17 62.9 1.4 1.9 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.22 001242422.1_39726001_1 - 5e-14 52.7 3.1 9.7e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001242422.1_39726001_1 - 0.017 15.2 0.0 0.047 13.9 0.0 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1764 PF08576.8 001242422.1_39726001_1 - 0.048 14.4 0.7 0.11 13.2 0.7 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) YihI PF04220.10 001242422.1_39726001_1 - 2.1 7.9 5.4 7 6.2 0.0 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) Reticulon PF02453.15 001033911.2_39723001_1 - 2.7e-47 160.5 6.7 3.8e-47 160.0 6.7 1.2 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.10 001033911.2_39723001_1 - 0.0079 15.5 1.6 0.012 14.9 1.6 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) DUF4736 PF15883.3 001033911.2_39723001_1 - 0.31 10.6 2.4 0.18 11.4 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Tubulin PF00091.23 001280428.1_39725001_2 - 1.1e-67 227.9 0.0 1.6e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001280428.1_39725001_2 - 6.8e-42 142.5 0.1 1.4e-41 141.5 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001280428.1_39725001_2 - 3.9e-05 23.8 0.0 8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001280428.1_39725001_2 - 0.03 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.4 001280428.1_39725001_2 - 0.036 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Chorion_2 PF03964.13 001280428.1_39725001_3 - 8.6 7.1 6.8 23 5.7 6.8 1.7 1 0 0 1 1 1 0 Chorion family 2 PBP PF01161.18 001280504.1_39725001_1 - 2.4e-08 34.2 0.0 4.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Aminotran_1_2 PF00155.19 001280432.1_39724001_1 - 5.2e-42 144.2 0.0 6.3e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II I-set PF07679.14 001329611.1_39729001_1 - 0 8422.3 284.6 1.3e-23 82.7 0.2 173.4 172 0 0 172 172 169 167 Immunoglobulin I-set domain fn3 PF00041.19 001329611.1_39729001_1 - 0 6222.3 336.1 8.3e-18 64.4 0.1 133.5 132 0 0 132 132 132 132 Fibronectin type III domain Ig_3 PF13927.4 001329611.1_39729001_1 - 0 4928.1 170.0 5.7e-15 55.6 0.3 167.8 167 0 0 167 167 165 163 Immunoglobulin domain Ig_2 PF13895.4 001329611.1_39729001_1 - 0 2601.9 205.2 1.1e-10 41.6 0.3 156.7 157 3 3 160 160 158 122 Immunoglobulin domain ig PF00047.23 001329611.1_39729001_1 - 0 2597.3 310.6 2.4e-10 40.3 0.6 157.1 161 0 0 161 161 157 129 Immunoglobulin domain V-set PF07686.15 001329611.1_39729001_1 - 7.8e-199 646.9 307.5 0.0043 17.1 0.0 148.7 147 39 0 147 147 140 35 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.3 001329611.1_39729001_1 - 6e-156 507.4 232.7 0.0044 17.4 0.0 107.9 116 4 0 116 116 106 33 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.3 001329611.1_39729001_1 - 1.5e-107 351.8 0.0 0.0018 18.2 0.0 69.3 80 0 0 80 80 75 11 Fibronectin type III domain C2-set_2 PF08205.10 001329611.1_39729001_1 - 3.4e-96 315.4 127.2 0.17 11.8 0.0 87.5 102 0 0 102 102 90 14 CD80-like C2-set immunoglobulin domain Titin_Z PF09042.9 001329611.1_39729001_1 - 2.5e-71 235.2 103.9 7.8e-12 44.8 15.2 8.1 7 0 0 7 7 7 7 Titin Z Receptor_2B4 PF11465.6 001329611.1_39729001_1 - 1.1e-66 221.7 125.8 0.06 13.4 0.0 78.3 91 2 2 93 93 80 7 Natural killer cell receptor 2B4 Pkinase PF00069.23 001329611.1_39729001_1 - 2.1e-56 191.0 0.7 4.5e-56 190.0 0.7 1.6 1 0 0 1 1 1 1 Protein kinase domain C1-set PF07654.13 001329611.1_39729001_1 - 9.9e-51 170.0 171.8 0.035 14.4 0.0 69.4 83 0 0 83 83 72 8 Immunoglobulin C1-set domain fn3_4 PF16794.3 001329611.1_39729001_1 - 3.7e-46 155.1 0.0 0.88 9.4 0.0 41.5 49 0 0 49 49 45 4 Fibronectin-III type domain DUF2369 PF10179.7 001329611.1_39729001_1 - 4.5e-29 100.6 9.6 0.66 10.4 0.0 30.1 37 0 0 37 37 26 3 Uncharacterised conserved protein (DUF2369) Pkinase_Tyr PF07714.15 001329611.1_39729001_1 - 4.5e-27 94.8 0.3 8.3e-27 94.0 0.3 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PPAK PF02818.13 001329611.1_39729001_1 - 1.9e-25 88.5 1701.6 3.6e-07 30.0 5.9 60.4 64 2 1 65 65 50 38 PPAK motif Izumo-Ig PF16706.3 001329611.1_39729001_1 - 2.8e-19 68.8 129.8 1.6 8.7 0.0 54.9 66 0 0 66 66 58 2 Izumo-like Immunoglobulin domain SusE PF14292.4 001329611.1_39729001_1 - 1.2e-16 61.1 50.2 2.4 8.4 0.0 34.3 40 1 3 43 43 30 1 SusE outer membrane protein Adeno_E3_CR1 PF02440.13 001329611.1_39729001_1 - 5.7e-15 54.7 104.3 0.43 10.3 0.2 43.6 56 0 0 56 56 49 4 Adenovirus E3 region protein CR1 Y_Y_Y PF07495.11 001329611.1_39729001_1 - 4.6e-07 29.6 73.0 13 5.7 0.1 38.5 56 0 0 56 56 46 0 Y_Y_Y domain DUF11 PF01345.16 001329611.1_39729001_1 - 2.8e-06 27.4 99.2 1.6 9.0 0.0 33.1 38 1 0 38 38 31 3 Domain of unknown function DUF11 Ig_4 PF16680.3 001329611.1_39729001_1 - 3.7 7.8 137.5 0.13 12.5 0.2 42.8 53 0 0 53 53 40 0 T-cell surface glycoprotein CD3 delta chain PPAK PF02818.13 001329611.1_39729001_3 - 6e-05 22.9 23.7 9.1e-05 22.3 23.7 1.3 1 0 0 1 1 1 1 PPAK motif VAD1-2 PF15310.4 001280184.1_39723001_3 - 1.2e-110 369.1 11.8 1.8e-110 368.6 11.8 1.2 1 0 0 1 1 1 1 Vitamin A-deficiency (VAD) rat model signalling CENP-T_N PF16171.3 001279995.1_39724001_2 - 1.3e-184 613.3 23.8 2e-184 612.7 23.8 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T N-terminus CENP-T_C PF15511.4 001279995.1_39724001_2 - 6.6e-36 122.6 0.1 1.1e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.4 001279995.1_39724001_2 - 3.5e-09 36.8 0.0 6.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.21 001279995.1_39724001_2 - 0.0015 18.7 0.1 0.0035 17.5 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.11 001279995.1_39724001_2 - 0.0021 17.9 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.22 001279995.1_39724001_2 - 0.0056 17.0 0.9 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.14 001279995.1_39724001_2 - 0.048 13.6 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit LETM1 PF07766.11 001280524.1_39724001_3 - 8.7e-98 326.8 10.2 1.1e-97 326.4 10.2 1.1 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.25 001280524.1_39724001_3 - 0.0081 15.8 0.8 0.035 13.8 0.1 2.3 2 0 0 2 2 2 1 SAP domain BPD_transp_1 PF00528.20 001280524.1_39724001_3 - 0.14 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF3573 PF12097.6 001280524.1_39724001_3 - 0.16 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) p47_phox_C PF08944.9 001252514.1_39721001_1 - 0.74 9.2 6.4 0.12 11.7 1.3 2.1 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Ribosomal_L36e PF01158.16 001252514.1_39721001_2 - 3e-51 171.5 8.4 3.6e-51 171.2 8.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e zf-H2C2_2 PF13465.4 001280164.1_39726001_1 - 3.4e-55 182.0 89.1 7.7e-08 32.3 1.1 14.9 14 1 0 14 14 14 10 Zinc-finger double domain zf-C2H2 PF00096.24 001280164.1_39726001_1 - 1.9e-37 125.5 90.2 1.1e-05 25.5 1.0 13.5 13 0 0 13 13 13 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280164.1_39726001_1 - 2.4e-16 58.9 89.0 0.0029 18.1 0.2 13.2 13 0 0 13 13 13 8 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001280164.1_39726001_1 - 0.0018 18.0 1.0 0.0018 18.0 1.0 10.5 11 0 0 11 11 11 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001280164.1_39726001_1 - 0.095 12.9 0.2 0.095 12.9 0.2 9.1 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.10 001280164.1_39726001_1 - 0.13 12.4 61.9 1.3 9.2 3.3 9.1 4 1 5 10 10 10 0 TFIIH C1-like domain BolA PF01722.16 001280164.1_39726001_1 - 0.15 12.2 10.5 2 8.6 0.4 4.6 3 2 0 4 4 4 0 BolA-like protein Ta0938 PF11494.6 001280164.1_39726001_1 - 7.8 6.7 8.6 0.63 10.2 0.8 3.0 3 1 0 3 3 3 0 Ta0938 zf-H2C2_2 PF13465.4 001280164.1_39726001_3 - 0.68 10.4 16.5 3.9 8.0 0.2 4.6 3 1 1 4 4 4 0 Zinc-finger double domain Transketolase_N PF00456.19 001243125.1_39726001_3 - 5e-42 143.9 0.0 9e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.22 001243125.1_39726001_3 - 4.4e-38 130.6 1.3 4.6e-38 130.5 0.2 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.18 001243125.1_39726001_3 - 4.8e-31 107.1 0.3 8.7e-31 106.3 0.3 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.18 001243125.1_39726001_3 - 1.4e-09 37.2 0.1 2.1e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.19 001243125.1_39726001_3 - 7e-05 22.5 0.0 0.00063 19.4 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.4 001243125.1_39726001_3 - 0.00084 18.5 0.0 0.034 13.2 0.0 2.3 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.8 001243125.1_39726001_3 - 0.0014 17.3 0.0 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain YjeF_N PF03853.13 001243125.1_39726001_3 - 0.0022 17.8 0.1 0.006 16.4 0.0 1.7 2 0 0 2 2 2 1 YjeF-related protein N-terminus CTP_transf_1 PF01148.18 001280219.1_39724001_1 - 1.4e-87 293.7 22.3 2.2e-87 293.1 22.3 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family 6PF2K PF01591.16 001280451.1_39724001_3 - 5e-103 343.1 1.8 7.8e-103 342.4 1.8 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.20 001280451.1_39724001_3 - 1.2e-41 142.4 0.0 1.8e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.4 001280451.1_39724001_3 - 5.3e-08 33.0 0.0 1.4e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.8 001280451.1_39724001_3 - 5.7e-05 22.6 0.1 0.00011 21.6 0.1 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 His_Phos_2 PF00328.20 001280451.1_39724001_3 - 0.022 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Radical_SAM PF04055.19 001280531.1_39723001_1 - 1.2e-15 58.2 0.1 4.6e-15 56.3 0.1 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.4 001280531.1_39723001_1 - 1.8e-07 31.3 0.1 3.4e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.4 001280531.1_39723001_1 - 2.8e-07 30.5 0.1 1.8e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Bax1-I PF01027.18 001279784.1_39724001_2 - 4.1e-39 134.4 13.6 5.9e-39 133.9 13.6 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Zip PF02535.20 001279850.1_39725001_2 - 9.2e-79 264.9 26.9 1.1e-78 264.7 5.3 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Mannosyl_trans PF05007.11 001246473.1_39725001_1 - 1.1e-106 356.4 27.4 1.6e-106 355.8 27.4 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.11 001246473.1_39725001_1 - 3.6e-13 49.2 33.4 5.7e-13 48.6 33.4 1.4 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Orai-1 PF07856.10 001246473.1_39725001_1 - 0.22 11.1 7.6 0.1 12.2 3.6 2.4 2 0 0 2 2 2 0 Mediator of CRAC channel activity DUF716 PF04819.10 001279861.1_39723001_1 - 1.1e-38 131.9 9.5 2.1e-38 131.0 9.5 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF716) zf-TRAF PF02176.16 001280267.1_39725001_1 - 5.7e-47 158.1 35.4 3.9e-21 75.4 4.5 4.7 1 1 3 4 4 4 3 TRAF-type zinc finger zf-C3HC4 PF00097.23 001280267.1_39725001_1 - 1.9e-07 30.7 3.5 1.9e-07 30.7 3.5 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001280267.1_39725001_1 - 8.2e-07 28.6 5.2 8.2e-07 28.6 5.2 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.4 001280267.1_39725001_1 - 1.2e-06 28.3 7.7 5.1e-06 26.3 7.7 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.6 001280267.1_39725001_1 - 0.00014 21.5 2.3 0.00014 21.5 2.3 2.7 4 0 0 4 4 4 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.4 001280267.1_39725001_1 - 0.00015 21.5 3.8 0.00015 21.5 3.8 3.3 3 1 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.4 001280267.1_39725001_1 - 0.00031 20.7 5.6 0.00031 20.7 5.6 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.4 001280267.1_39725001_1 - 0.0005 20.2 4.5 0.0005 20.2 4.5 3.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_6 PF14835.4 001280267.1_39725001_1 - 0.0005 19.7 1.2 0.0015 18.2 1.2 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.4 001280267.1_39725001_1 - 0.00088 19.0 2.1 0.00088 19.0 2.1 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.3 001280267.1_39725001_1 - 0.0037 17.6 34.6 0.25 11.7 6.5 4.8 1 1 3 4 4 4 3 TRAF-like zinc-finger Sina PF03145.14 001280267.1_39725001_1 - 0.0047 16.8 2.6 0.0047 16.8 2.6 4.0 1 1 4 5 5 4 1 Seven in absentia protein family zf-rbx1 PF12678.5 001280267.1_39725001_1 - 0.013 15.6 1.8 0.013 15.6 1.8 3.3 2 1 1 3 3 2 0 RING-H2 zinc finger domain MATH PF00917.24 001280267.1_39725001_1 - 0.014 15.4 0.0 1.1 9.3 0.0 2.3 1 1 1 2 2 2 0 MATH domain 7tm_1 PF00001.19 001146253.1_39723001_1 - 3.7e-50 170.5 17.3 1e-49 169.1 17.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001146253.1_39723001_1 - 5.8e-06 25.7 14.4 7.4e-06 25.4 14.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Peptidase_M24 PF00557.22 001280530.1_39724001_2 - 2.2e-57 194.0 0.0 3.2e-56 190.2 0.1 2.5 3 0 0 3 3 3 1 Metallopeptidase family M24 AMP_N PF05195.14 001280530.1_39724001_2 - 3.8e-30 104.0 0.0 6.6e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.5 001280530.1_39724001_2 - 0.066 13.1 0.2 0.55 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) Snf7 PF03357.19 001302415.1_39724001_1 - 3.3e-56 189.5 17.7 3.3e-56 189.5 17.7 2.1 2 0 0 2 2 2 1 Snf7 AlbA_2 PF04326.12 001246488.1_39725001_3 - 5.1e-28 97.7 0.0 8.2e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Putative DNA-binding domain bZIP_1 PF00170.19 001246488.1_39725001_3 - 0.042 13.8 0.9 0.081 12.9 0.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor M16C_assoc PF08367.9 001280465.1_39727001_2 - 2.5e-84 282.2 0.0 3.8e-84 281.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.19 001280465.1_39727001_2 - 1.9e-37 128.9 0.2 3.7e-26 92.1 0.0 3.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.18 001280465.1_39727001_2 - 2.5e-09 37.2 0.3 2e-05 24.5 0.0 3.3 3 1 0 3 3 3 2 Insulinase (Peptidase family M16) V-SNARE_C PF12352.6 001252011.2_39723001_1 - 2.8e-20 72.2 8.0 2.8e-20 72.2 8.0 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.13 001252011.2_39723001_1 - 1.2e-18 67.2 0.4 1.2e-18 67.2 0.4 2.1 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.11 001252011.2_39723001_1 - 1.5e-05 24.7 2.3 4.1e-05 23.3 1.9 2.0 2 0 0 2 2 2 1 Sec20 Laminin_II PF06009.10 001252011.2_39723001_1 - 0.0024 17.8 3.8 0.22 11.4 1.2 2.8 2 1 1 3 3 3 1 Laminin Domain II YqjK PF13997.4 001252011.2_39723001_1 - 0.0054 16.8 1.3 4.5 7.4 0.4 2.7 2 0 0 2 2 2 2 YqjK-like protein Fusion_gly PF00523.16 001252011.2_39723001_1 - 0.0093 14.1 0.4 0.015 13.4 0.4 1.3 1 0 0 1 1 1 1 Fusion glycoprotein F0 DUF3376 PF11856.6 001252011.2_39723001_1 - 0.0096 14.8 1.0 0.02 13.7 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3376) OmpH PF03938.12 001252011.2_39723001_1 - 1.1 9.1 5.0 0.5 10.2 0.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF745 PF05335.11 001252011.2_39723001_1 - 1.7 8.2 6.8 3.5 7.2 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1759 PF03564.13 001252011.2_39723001_1 - 2.1 8.2 5.1 4.7 7.0 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) KxDL PF10241.7 001252011.2_39723001_1 - 3.2 8.0 11.3 4.6 7.5 0.3 3.6 3 1 1 4 4 4 0 Uncharacterized conserved protein Exonuc_VII_L PF02601.13 001252011.2_39723001_1 - 5.1 6.4 10.5 17 4.7 10.5 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.9 001252011.2_39723001_1 - 5.3 7.5 7.8 13 6.3 2.9 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal PRIMA1 PF16101.3 001252011.2_39723001_2 - 0.33 10.9 6.1 0.68 9.8 6.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SPAN-X PF07458.10 001009153.1_39721001_1 - 3.9e-40 136.0 2.7 4.4e-40 135.9 2.7 1.0 1 0 0 1 1 1 1 Sperm protein associated with nucleus, mapped to X chromosome Methyltransf_32 PF13679.4 001279831.1_39724001_3 - 2.2e-31 108.9 4.8 9.7e-30 103.5 4.8 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.4 001279831.1_39724001_3 - 0.00071 19.4 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.4 001279831.1_39724001_3 - 0.00099 18.8 0.0 0.003 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001279831.1_39724001_3 - 0.001 19.6 0.0 0.0034 17.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.10 001279831.1_39724001_3 - 0.0037 17.7 0.0 0.023 15.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.11 001279831.1_39724001_3 - 0.006 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.12 001279831.1_39724001_3 - 0.035 13.5 0.2 0.33 10.3 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase small domain Ndr PF03096.12 001279831.1_39724001_3 - 0.043 12.4 0.0 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Ndr family Methyltransf_12 PF08242.10 001279831.1_39724001_3 - 0.092 13.3 0.1 0.34 11.5 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_C26 PF07722.11 001279831.1_39724001_3 - 0.11 12.2 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase C26 7tm_4 PF13853.4 001168366.1_39722001_1 - 1.8e-49 168.8 19.8 2.1e-49 168.6 19.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001168366.1_39722001_1 - 8.9e-24 84.0 24.3 2.7e-23 82.4 24.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001168366.1_39722001_1 - 4.8e-05 22.7 18.8 6.7e-05 22.3 18.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001168366.1_39722001_1 - 0.00073 18.8 16.9 0.00098 18.4 16.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CPP1-like PF11833.6 001168366.1_39722001_1 - 7.9 5.9 8.1 0.41 10.1 2.1 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like 7tm_4 PF13853.4 001009113.1_39722001_1 - 4.2e-48 164.4 23.7 5.1e-48 164.1 23.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001009113.1_39722001_1 - 8.5e-27 93.9 25.0 1.5e-26 93.1 25.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001009113.1_39722001_1 - 2e-07 30.5 10.6 2e-07 30.5 10.6 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Peptidase_S10 PF00450.20 001246611.1_39724001_2 - 2.4e-104 350.0 0.2 3.2e-104 349.5 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Lamp PF01299.15 001328292.1_39724001_1 - 7.8e-77 258.8 6.7 7.8e-77 258.8 6.7 2.1 1 1 1 2 2 2 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.10 001328292.1_39724001_1 - 9.4e-08 31.9 0.1 1.9e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PCI PF01399.25 001280192.1_39724001_3 - 3.6e-13 49.8 0.0 9.7e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 PCI domain Lyase_1 PF00206.18 001280243.1_39724001_1 - 1.3e-123 412.3 0.1 1.6e-123 411.9 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.7 001280243.1_39724001_1 - 3.6e-27 94.4 0.4 1.3e-26 92.6 0.1 2.1 2 0 0 2 2 2 1 Fumarase C C-terminus YadA_anchor PF03895.13 001280243.1_39724001_1 - 0.21 11.8 2.5 0.44 10.8 0.2 2.6 2 0 0 2 2 2 0 YadA-like C-terminal region DUF3583 PF12126.6 001042435.1_39726001_1 - 1.3e-180 599.8 8.7 1.9e-180 599.3 8.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-B_box PF00643.22 001042435.1_39726001_1 - 5.6e-08 32.7 4.3 5.6e-08 32.7 4.3 3.8 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_3 PF13920.4 001042435.1_39726001_1 - 0.00013 21.6 10.9 0.00013 21.6 10.9 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001042435.1_39726001_1 - 0.0032 17.1 13.0 0.0032 17.1 13.0 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.4 001042435.1_39726001_1 - 0.0074 16.1 12.3 0.0074 16.1 12.3 3.3 3 0 0 3 3 3 2 zinc-RING finger domain OmpH PF03938.12 001042435.1_39726001_1 - 0.033 14.0 4.0 0.082 12.8 4.0 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cep57_CLD_2 PF14197.4 001042435.1_39726001_1 - 1.3 9.0 7.9 0.12 12.3 2.2 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 FBA PF04300.11 001246404.1_39724001_3 - 5.8e-74 247.7 0.0 7.7e-74 247.3 0.0 1.1 1 0 0 1 1 1 1 F-box associated region F-box-like PF12937.5 001246404.1_39724001_3 - 1.3e-08 34.5 4.1 2.4e-08 33.6 4.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001246404.1_39724001_3 - 7e-08 32.0 4.3 1.2e-07 31.3 4.3 1.4 1 0 0 1 1 1 1 F-box domain Asn_synthase PF00733.19 001280402.1_39724001_1 - 8.4e-85 285.4 0.8 1.1e-47 163.3 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.4 001280402.1_39724001_1 - 3.5e-24 85.0 0.0 5.9e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.4 001280402.1_39724001_1 - 3.7e-18 65.9 0.0 8.5e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.6 001280402.1_39724001_1 - 2.6e-06 26.9 0.0 5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.14 001280402.1_39724001_1 - 0.0093 14.7 0.0 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.15 001280402.1_39724001_1 - 0.051 12.6 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Cloacin_immun PF03513.12 001280402.1_39724001_1 - 0.054 13.7 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Cloacin immunity protein QueC PF06508.11 001280402.1_39724001_1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Cgr1 PF03879.12 001246553.1_39724001_2 - 5.7e-16 58.7 31.1 1.1e-15 57.8 31.1 1.4 1 0 0 1 1 1 1 Cgr1 family AGOG PF09171.8 001246553.1_39724001_2 - 4.2 6.5 6.5 6 6.0 6.5 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase CN_hydrolase PF00795.20 001302434.1_39725001_3 - 2.9e-13 49.6 0.0 4.6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_M1 PF01433.18 001280082.1_39725001_3 - 3.3e-78 263.5 0.0 4.4e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.9 001280082.1_39725001_3 - 5e-44 149.6 0.3 8.4e-44 148.9 0.3 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal E1_DerP2_DerF2 PF02221.13 001280082.1_39725001_3 - 0.019 15.3 0.1 0.043 14.1 0.1 1.5 1 0 0 1 1 1 0 ML domain Peptidase_M48 PF01435.16 001280082.1_39725001_3 - 0.14 11.8 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 UPF0020 PF01170.16 001280225.1_39724001_3 - 8.4e-50 169.1 0.0 1.3e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.15 001280225.1_39724001_3 - 1.7e-11 44.2 1.5 1.4e-10 41.3 0.5 2.5 1 1 1 2 2 2 1 THUMP domain Methyltransf_25 PF13649.4 001280225.1_39724001_3 - 0.00012 22.6 0.0 0.00038 21.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.12 001280225.1_39724001_3 - 0.0053 16.2 0.0 0.85 9.0 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase small domain Fer4_NifH PF00142.16 001280225.1_39724001_3 - 0.066 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ubiquitin PF00240.21 001242421.2_39723001_3 - 8.3e-20 70.2 0.0 1.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.6 001242421.2_39723001_3 - 1.6e-08 34.1 0.0 2.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001242421.2_39723001_3 - 0.03 14.7 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Insulin PF00049.16 001177815.1_39722001_1 - 1.1e-06 29.5 2.0 3.9e-06 27.6 2.0 1.9 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.12 001177815.1_39722001_1 - 0.049 13.5 3.2 4.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type GpcrRhopsn4 PF10192.7 001280489.1_39725001_1 - 4.3e-79 265.4 16.9 4.3e-79 265.4 16.9 1.9 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.11 001280489.1_39725001_1 - 0.0038 16.3 8.6 0.0095 15.0 8.6 1.7 1 0 0 1 1 1 1 Lung seven transmembrane receptor 7tm_1 PF00001.19 001195264.1_39725001_3 - 6.4e-69 232.0 14.2 8.7e-69 231.6 14.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001195264.1_39725001_3 - 9.3e-14 51.3 17.1 1.4e-13 50.7 17.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.4 001195264.1_39725001_3 - 1.8e-07 31.1 9.9 1.8e-07 31.1 9.9 1.9 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001195264.1_39725001_3 - 2.2e-06 27.1 16.8 4.2e-06 26.1 16.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Filament PF00038.19 001098554.1_39725001_2 - 1.3e-97 327.1 55.0 1.7e-97 326.7 55.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.17 001098554.1_39725001_2 - 9.8e-18 64.4 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain Fez1 PF06818.13 001098554.1_39725001_2 - 0.0012 19.2 25.0 0.0012 19.2 25.0 3.3 1 1 2 3 3 3 1 Fez1 Reo_sigmaC PF04582.10 001098554.1_39725001_2 - 0.0013 18.1 14.2 0.018 14.3 0.6 3.2 1 1 2 3 3 3 3 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.10 001098554.1_39725001_2 - 0.0024 17.8 59.9 0.22 11.4 26.0 4.3 1 1 3 4 4 4 3 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.4 001098554.1_39725001_2 - 0.0045 16.4 6.7 0.0045 16.4 6.7 3.9 1 1 2 3 3 2 1 HAUS augmin-like complex subunit 3 IncA PF04156.12 001098554.1_39725001_2 - 0.033 13.8 70.1 0.11 12.2 22.3 4.0 1 1 1 2 2 1 0 IncA protein Tht1 PF04163.10 001098554.1_39725001_2 - 0.24 10.0 7.5 0.36 9.4 7.5 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein CENP-F_leu_zip PF10473.7 001098554.1_39725001_2 - 0.33 10.8 57.1 0.67 9.8 11.3 3.5 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.9 001098554.1_39725001_2 - 0.74 8.5 52.5 2 7.1 9.0 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.6 001098554.1_39725001_2 - 4.2 4.6 51.7 10 3.3 51.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.4 001098554.1_39725001_2 - 7.1 5.7 48.7 60 2.7 22.3 4.1 1 1 1 2 2 1 0 Domain of unknown function (DUF4407) HAP1_N PF04849.11 001098554.1_39725001_2 - 9.2 5.2 52.3 0.16 11.0 14.9 2.7 1 1 1 2 2 2 0 HAP1 N-terminal conserved region ATG16 PF08614.9 001098554.1_39725001_2 - 9.9 6.2 76.6 0.014 15.5 25.6 4.3 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF4113 PF13438.4 001098554.1_39725001_3 - 0.073 13.0 2.4 0.21 11.6 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) SUI1 PF01253.20 001202487.1_39725001_1 - 4.8e-19 68.5 0.0 1.5e-18 67.0 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.18 001202487.1_39725001_1 - 0.00065 19.5 0.1 0.003 17.4 0.1 2.0 2 0 0 2 2 2 1 PUA domain DUF2771 PF10969.6 001202487.1_39725001_1 - 0.0023 17.9 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2771) LSM PF01423.20 001280532.1_39724001_1 - 1.7e-19 69.2 0.1 2.3e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain KRAB PF01352.25 001280532.1_39724001_3 - 7.8e-22 76.5 0.1 1.4e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 KRAB box Cpn60_TCP1 PF00118.22 001280124.1_39724001_3 - 2.8e-159 530.7 2.5 3.2e-159 530.6 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SR-25 PF10500.7 001246489.1_39724001_1 - 3.7 6.9 14.8 5.1 6.5 14.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein His_Phos_2 PF00328.20 001246489.1_39724001_2 - 1e-34 120.4 0.2 3.2e-32 112.2 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Carb_anhydrase PF00194.19 001194924.1_39723001_1 - 1.8e-97 325.7 0.0 2.1e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase tRNA-synt_1d PF00750.17 001279969.1_39725001_1 - 1.1e-95 320.4 0.9 1.6e-95 319.9 0.9 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.13 001279969.1_39725001_1 - 2.1e-20 73.0 0.0 4.7e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain DALR_2 PF09190.9 001279969.1_39725001_1 - 0.62 10.5 2.4 0.92 9.9 0.1 2.4 2 0 0 2 2 2 0 DALR domain Tektin PF03148.12 001302413.1_39724001_3 - 5.1e-18 64.9 12.7 6.9e-18 64.4 12.7 1.1 1 0 0 1 1 1 1 Tektin family DSPn PF14671.4 001280197.1_39724001_1 - 1e-56 191.2 2.6 6.2e-56 188.6 1.6 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.18 001280197.1_39724001_1 - 2.4e-15 56.4 0.0 5.4e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.4 001280197.1_39724001_1 - 1.6e-06 28.2 0.0 2.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.25 001280197.1_39724001_1 - 1.9e-05 24.3 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.4 001280197.1_39724001_1 - 0.019 14.8 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.10 001280197.1_39724001_1 - 0.036 13.6 0.8 0.094 12.2 0.1 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Crystall PF00030.17 001135661.1_39722001_3 - 1.5e-64 214.0 1.3 1.4e-31 108.4 0.5 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001135661.1_39722001_3 - 4.7e-05 23.1 0.0 0.015 15.1 0.2 2.3 2 0 0 2 2 2 2 Peptidase inhibitor family I36 Pou PF00157.15 001279883.2_39725001_3 - 3.1e-38 129.5 0.2 7e-38 128.4 0.2 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001279883.2_39725001_3 - 1.9e-17 62.7 3.5 5e-17 61.3 3.5 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001279883.2_39725001_3 - 0.027 14.2 0.2 0.084 12.7 0.2 1.9 1 0 0 1 1 1 0 Homeobox KN domain HTH_31 PF13560.4 001279883.2_39725001_3 - 1.3 9.3 0.0 1.3 9.3 0.0 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain F-actin_cap_A PF01267.15 001246575.2_39724001_3 - 6.3e-61 206.0 0.0 8.4e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit HemN_C PF06969.14 001246575.2_39724001_3 - 0.24 11.3 1.1 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 HemN C-terminal domain CSN8_PSD8_EIF3K PF10075.7 001251986.1_39724001_2 - 4.1e-36 124.0 0.1 5.7e-36 123.5 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family zf-LYAR PF08790.9 001280007.1_39724001_3 - 1.3e-15 56.8 1.6 1.3e-15 56.8 1.6 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DEK_C PF08766.9 001280007.1_39724001_3 - 0.026 14.3 0.2 0.097 12.5 0.1 2.1 2 0 0 2 2 2 0 DEK C terminal domain Mut7-C PF01927.14 001280007.1_39724001_3 - 0.12 12.3 4.3 0.28 11.1 4.3 1.6 1 0 0 1 1 1 0 Mut7-C RNAse domain IL28A PF15177.4 001276259.1_39723001_3 - 1.5e-35 122.3 0.3 2e-35 121.8 0.3 1.2 1 0 0 1 1 1 1 Interleukin-28A TFIIA PF03153.11 001204826.1_39724001_3 - 1.4e-129 433.6 0.4 1.6e-129 433.4 0.4 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit HSP90 PF00183.16 001246487.1_39726001_1 - 1.3e-229 763.2 28.5 1.3e-229 763.2 28.5 1.7 1 1 1 2 2 2 1 Hsp90 protein HATPase_c PF02518.24 001246487.1_39726001_1 - 1.2e-13 51.5 0.4 2e-13 50.7 0.4 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001246487.1_39726001_1 - 4.7e-11 42.5 0.4 1.2e-10 41.2 0.4 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4518 PF15008.4 001246487.1_39726001_1 - 0.043 12.8 4.1 0.92 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Ribosomal_L3 PF00297.20 001280310.1_39724001_2 - 3e-98 329.1 0.0 7.3e-69 232.4 0.0 3.0 1 1 1 2 2 2 2 Ribosomal protein L3 RRM_5 PF13893.4 001280153.1_39725001_2 - 1.6e-60 202.1 0.0 2.9e-50 168.9 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 001280153.1_39725001_2 - 2.1e-22 78.6 0.4 3.1e-08 33.2 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001280153.1_39725001_2 - 2.6e-07 30.2 0.0 0.21 11.3 0.0 3.3 3 0 0 3 3 3 3 Occluded RNA-recognition motif DUF4523 PF15023.4 001280153.1_39725001_2 - 0.00012 21.8 0.1 0.00046 19.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) Dscam_C PF12355.6 001280153.1_39725001_2 - 0.00025 21.9 0.3 0.00066 20.5 0.3 1.7 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal Limkain-b1 PF11608.6 001280153.1_39725001_2 - 0.00026 20.9 0.0 0.52 10.3 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.9 001280153.1_39725001_2 - 0.073 13.0 1.1 0.8 9.7 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif TMEM100 PF16311.3 001280153.1_39725001_2 - 0.18 11.2 0.3 0.33 10.4 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 PCI PF01399.25 001246477.1_39724001_3 - 1.1e-17 64.3 1.8 2.3e-17 63.3 1.8 1.6 1 0 0 1 1 1 1 PCI domain zf-RanBP PF00641.16 001280166.1_39725001_1 - 1.2 8.4 4.1 3.6 6.9 0.3 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF4471 PF14740.4 001280166.1_39725001_2 - 1.1e-104 349.8 0.0 2e-104 348.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.4 001280166.1_39725001_2 - 1.4e-25 89.1 0.0 2.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) CLTH PF10607.7 001280502.1_39724001_2 - 5.5e-32 110.5 0.0 1.4e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.4 001280502.1_39724001_2 - 0.00028 20.7 0.1 0.00028 20.7 0.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.10 001280502.1_39724001_2 - 0.0097 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Sec15 PF04091.10 001280502.1_39724001_2 - 0.049 12.9 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like WD40 PF00400.30 001246428.1_39724001_3 - 1.1e-40 136.7 34.8 5.3e-07 30.1 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001246428.1_39724001_3 - 2.4e-09 37.2 0.8 0.43 10.8 0.1 5.8 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 001246428.1_39724001_3 - 1.4e-07 30.5 12.2 0.038 12.5 0.0 4.3 2 1 1 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.4 001246428.1_39724001_3 - 4.8e-05 22.9 0.1 9e-05 22.0 0.1 1.6 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.19 001246428.1_39724001_3 - 6.2e-05 22.6 0.1 0.00018 21.2 0.1 1.8 1 0 0 1 1 1 1 PQQ enzyme repeat Ge1_WD40 PF16529.3 001246428.1_39724001_3 - 0.00032 19.6 5.0 0.68 8.7 0.1 4.4 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.9 001246428.1_39724001_3 - 0.0012 18.7 1.3 1.6 8.4 0.6 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.14 001246428.1_39724001_3 - 0.0014 17.1 0.1 0.01 14.3 0.0 2.1 1 1 0 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.9 001246428.1_39724001_3 - 0.023 13.3 2.7 1.3 7.6 0.3 2.9 2 1 1 3 3 3 0 Nup133 N terminal like WD40_like PF17005.3 001246428.1_39724001_3 - 0.032 13.4 0.7 5 6.2 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PQQ_3 PF13570.4 001246428.1_39724001_3 - 0.057 13.8 0.0 2 8.9 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain RRM_1 PF00076.20 001251847.1_39727001_1 - 4.2e-30 103.2 0.1 1.3e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.9 001251847.1_39727001_1 - 5.5e-28 96.7 1.0 1.1e-27 95.7 1.0 1.6 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.3 001251847.1_39727001_1 - 0.0012 18.8 0.0 0.0059 16.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif Homeobox PF00046.27 001251889.1_39724001_1 - 3.1e-20 71.6 2.4 6.7e-20 70.5 2.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.9 001251889.1_39724001_1 - 0.014 15.1 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain PRIMA1 PF16101.3 001251889.1_39724001_1 - 1.1 9.1 11.5 3.3 7.7 11.5 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.17 001251889.1_39724001_1 - 5.4 6.3 18.1 0.16 11.3 11.1 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.9 001251889.1_39724001_1 - 7.1 6.5 15.7 0.39 10.6 9.2 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator CCDC106 PF15794.3 001251889.1_39724001_2 - 0.94 9.0 7.4 1.4 8.4 7.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.7 001251889.1_39724001_2 - 1 8.8 29.8 1.3 8.5 28.6 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4603 PF15376.4 001251889.1_39724001_2 - 3 5.0 18.5 4.2 4.5 18.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) UPF0193 PF05250.9 001280139.1_39723001_3 - 7.3e-90 300.4 6.2 1e-89 299.9 6.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) Myb_DNA-bind_5 PF13873.4 001280139.1_39723001_3 - 0.16 12.0 1.6 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SRP54 PF00448.20 001280526.1_39724001_1 - 1.9e-78 262.5 1.2 9.5e-78 260.2 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.17 001280526.1_39724001_1 - 3.1e-30 104.6 2.7 3.1e-30 104.6 2.7 3.3 2 1 2 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.17 001280526.1_39724001_1 - 4.3e-21 74.8 3.1 1.2e-20 73.4 3.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.17 001280526.1_39724001_1 - 9.1e-07 28.5 1.0 1.2e-05 24.9 1.0 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.4 001280526.1_39724001_1 - 1.3e-06 28.5 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.21 001280526.1_39724001_1 - 2.2e-05 24.4 0.0 9.3e-05 22.4 0.0 2.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.4 001280526.1_39724001_1 - 0.0001 22.6 0.7 0.00046 20.5 0.1 2.5 2 1 0 2 2 1 1 AAA domain DUF2209 PF09974.7 001280526.1_39724001_1 - 0.0002 21.5 0.3 0.00052 20.2 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) SRPRB PF09439.8 001280526.1_39724001_1 - 0.00025 20.4 0.5 0.77 9.0 0.0 2.6 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit CLP1_P PF16575.3 001280526.1_39724001_1 - 0.00064 19.4 0.8 0.89 9.2 0.1 2.5 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop ArgK PF03308.14 001280526.1_39724001_1 - 0.0009 18.2 0.2 0.022 13.6 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_30 PF13604.4 001280526.1_39724001_1 - 0.0026 17.4 0.1 0.0081 15.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.18 001280526.1_39724001_1 - 0.0037 17.0 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.4 001280526.1_39724001_1 - 0.0044 17.3 0.0 0.0098 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.27 001280526.1_39724001_1 - 0.0057 16.9 1.3 0.051 13.9 0.1 3.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.13 001280526.1_39724001_1 - 0.0059 16.5 0.3 0.017 15.0 0.3 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.4 001280526.1_39724001_1 - 0.0072 16.5 0.7 0.047 13.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.21 001280526.1_39724001_1 - 0.009 16.0 1.8 0.024 14.6 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.16 001280526.1_39724001_1 - 0.014 14.6 0.0 0.037 13.2 0.0 1.7 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MobB PF03205.12 001280526.1_39724001_1 - 0.018 14.8 0.5 0.055 13.2 0.0 2.1 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.15 001280526.1_39724001_1 - 0.019 14.5 0.0 0.055 13.0 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase AAA_28 PF13521.4 001280526.1_39724001_1 - 0.028 14.5 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.15 001280526.1_39724001_1 - 0.029 14.0 2.8 0.067 12.8 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.4 001280526.1_39724001_1 - 0.029 14.8 0.1 0.08 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.10 001280526.1_39724001_1 - 0.04 13.1 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_31 PF13614.4 001280526.1_39724001_1 - 0.047 13.5 1.2 0.13 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.4 001280526.1_39724001_1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Torsin PF06309.9 001280526.1_39724001_1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Torsin G-alpha PF00503.18 001280526.1_39724001_1 - 0.091 11.8 0.7 1.1 8.2 0.1 2.4 2 1 0 3 3 3 0 G-protein alpha subunit Lyase_1 PF00206.18 001280160.1_39724001_1 - 3.2e-26 92.3 0.0 4.6e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.7 001280160.1_39724001_1 - 7.8e-19 67.9 0.0 2e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.4 001280160.1_39724001_1 - 0.0081 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4089) HTH_Tnp_Tc5 PF03221.14 001280160.1_39724001_1 - 0.043 13.7 0.9 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DUF1331 PF07048.9 001280160.1_39724001_1 - 0.064 12.8 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) SPATIAL PF15256.4 001280178.1_39724001_3 - 1.7e-55 188.4 0.0 3.2e-55 187.4 0.0 1.5 1 0 0 1 1 1 1 SPATIAL SIR2_2 PF13289.4 001280312.1_39724001_3 - 7.5e-10 38.9 0.4 7.8e-05 22.7 0.0 2.5 1 1 1 2 2 2 2 SIR2-like domain AMP-binding PF00501.26 001246607.1_39726001_2 - 8.9e-87 291.2 0.0 1.1e-86 291.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.8 001246607.1_39726001_2 - 0.012 15.6 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) CTP_transf_3 PF02348.17 001280379.1_39724001_3 - 9.7e-65 218.4 0.0 1.3e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.5 001280379.1_39724001_3 - 1.1e-06 29.0 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hydrolase_3 PF08282.10 001280379.1_39724001_3 - 0.054 13.1 0.0 0.54 9.8 0.0 2.4 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF1593 PF07632.9 001280379.1_39724001_3 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) INT_SG_DDX_CT_C PF15300.4 001280238.1_39727001_3 - 5.1e-27 93.3 3.6 1.4e-26 91.9 3.6 1.8 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA_2 PF13519.4 001280238.1_39727001_3 - 7.6e-22 77.9 0.0 1.6e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.26 001280238.1_39727001_3 - 0.00069 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4604 PF15377.4 001246360.1_39724001_1 - 0.013 15.8 10.2 0.017 15.4 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF4604 PF15377.4 001246360.1_39724001_2 - 0.073 13.4 13.7 0.1 12.9 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Actin PF00022.17 001246360.1_39724001_3 - 1.2e-100 336.9 1.7 1.3e-99 333.5 0.0 2.3 2 1 0 2 2 2 1 Actin ACTL7A_N PF16840.3 001246360.1_39724001_3 - 2.6e-34 116.9 5.0 2.6e-34 116.9 5.0 1.9 2 0 0 2 2 2 1 Actin-like protein 7A N-terminus MreB_Mbl PF06723.11 001246360.1_39724001_3 - 1.5e-05 23.8 0.0 0.05 12.3 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein N6_Mtase PF02384.14 001246360.1_39724001_3 - 0.032 13.4 0.1 0.061 12.4 0.1 1.4 1 0 0 1 1 1 0 N-6 DNA Methylase Rxt3 PF08642.8 001246360.1_39724001_3 - 0.36 11.5 2.9 0.19 12.3 0.7 1.7 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 SR-25 PF10500.7 001246360.1_39724001_3 - 0.42 10.1 25.3 0.76 9.2 25.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F-box-like PF12937.5 001279988.1_39725001_2 - 1.8e-10 40.4 0.1 4.6e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001279988.1_39725001_2 - 4.3e-10 39.1 0.8 1.6e-09 37.3 0.1 2.4 3 0 0 3 3 3 1 F-box domain RCC1 PF00415.16 001279988.1_39725001_2 - 8e-07 29.4 0.2 8e-07 29.4 0.2 2.1 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.4 001279988.1_39725001_2 - 0.19 12.1 0.1 1.8 8.9 0.0 2.4 3 0 0 3 3 3 0 SUKH-3 immunity protein Pkinase PF00069.23 001246574.1_39725001_3 - 5.6e-75 252.0 0.1 1.8e-74 250.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001246574.1_39725001_3 - 4.3e-36 124.4 0.0 6.8e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001246574.1_39725001_3 - 1.4e-06 27.7 0.3 3.7e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.20 001246574.1_39725001_3 - 0.00028 20.4 0.0 0.00057 19.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.18 001246574.1_39725001_3 - 0.0055 16.2 0.1 0.32 10.4 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.4 001246574.1_39725001_3 - 0.0077 15.4 0.2 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.4 001246574.1_39725001_3 - 0.042 13.4 0.0 10 5.6 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 OmpH PF03938.12 001246574.1_39725001_3 - 1.6 8.6 7.4 3.5 7.5 7.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SH3_9 PF14604.4 001242392.1_39729001_2 - 8e-50 166.4 4.7 2.2e-10 40.1 0.0 6.5 6 0 0 6 6 6 5 Variant SH3 domain BAR PF03114.16 001242392.1_39729001_2 - 9.4e-50 169.3 4.5 9.4e-50 169.3 4.5 2.0 2 0 0 2 2 2 1 BAR domain SH3_1 PF00018.26 001242392.1_39729001_2 - 1.1e-49 165.7 0.7 4.4e-11 42.1 0.0 6.6 6 0 0 6 6 6 6 SH3 domain SH3_2 PF07653.15 001242392.1_39729001_2 - 1.2e-43 146.5 1.6 5e-07 29.2 0.0 6.5 6 0 0 6 6 6 6 Variant SH3 domain RhoGEF PF00621.18 001242392.1_39729001_2 - 2.1e-36 125.7 0.3 2.1e-36 125.7 0.3 2.2 2 1 0 2 2 2 1 RhoGEF domain SH3_3 PF08239.9 001242392.1_39729001_2 - 0.024 14.8 0.6 0.076 13.2 0.3 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain LSM PF01423.20 001256797.1_39723001_1 - 1.1e-19 69.8 0.1 1.4e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SNURF PF07192.9 001256797.1_39723001_2 - 5.8e-45 150.8 6.1 9.5e-45 150.1 6.1 1.4 1 0 0 1 1 1 1 SNURF/RPN4 protein Tap-RNA_bind PF09162.8 001246508.1_39724001_1 - 4.1e-36 122.6 0.1 7.8e-36 121.7 0.1 1.5 1 0 0 1 1 1 1 Tap, RNA-binding NTF2 PF02136.18 001246508.1_39724001_1 - 1.1e-16 61.4 0.1 3.1e-16 59.9 0.1 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Crystall PF00030.17 001100602.1_39722001_1 - 1.1e-62 208.0 0.9 7.3e-32 109.3 1.0 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001100602.1_39722001_1 - 0.043 13.6 3.5 2.1 8.2 1.1 3.4 1 1 3 4 4 4 0 Peptidase inhibitor family I36 Crystall_3 PF08964.8 001100602.1_39722001_1 - 0.07 13.2 0.1 2.7 8.1 0.0 2.5 3 0 0 3 3 3 0 Beta/Gamma crystallin Lamp PF01299.15 001246562.1_39725001_1 - 1.7e-131 438.3 2.2 3.8e-126 420.8 0.2 2.1 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.10 001246562.1_39725001_1 - 9.1e-07 28.7 0.3 0.00043 20.0 0.0 2.5 2 0 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) EF-hand_7 PF13499.4 001280447.1_39725001_2 - 2.4e-13 50.2 1.3 4.4e-08 33.4 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001280447.1_39725001_2 - 4.5e-12 44.7 0.4 0.0013 18.3 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.30 001280447.1_39725001_2 - 2.9e-11 41.9 0.1 0.012 15.0 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.4 001280447.1_39725001_2 - 3.4e-10 38.8 0.0 0.029 13.8 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.4 001280447.1_39725001_2 - 1.6e-06 27.6 0.2 0.0073 15.9 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001280447.1_39725001_2 - 6.1e-06 26.4 0.0 0.0097 16.1 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region PDZ PF00595.22 001280008.1_39724001_2 - 1.4e-16 60.5 2.7 9.4e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001280008.1_39724001_2 - 7.2e-10 38.9 0.4 9e-06 25.8 0.0 2.4 1 1 1 2 2 2 2 PDZ domain Oxygenase-NA PF09859.7 001280008.1_39724001_2 - 0.15 11.5 0.3 0.32 10.4 0.3 1.5 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA FAM47 PF14642.4 001328284.1_39725001_1 - 3.5e-182 603.4 60.0 1.4e-134 447.4 18.6 4.4 1 1 3 4 4 4 4 FAM47 family Drf_FH1 PF06346.10 001328284.1_39725001_1 - 0.039 13.5 34.6 0.018 14.6 18.8 2.5 1 1 1 2 2 2 0 Formin Homology Region 1 Drf_FH1 PF06346.10 001328284.1_39725001_3 - 0.18 11.4 18.9 0.068 12.7 13.0 2.3 1 1 1 2 2 2 0 Formin Homology Region 1 7tm_1 PF00001.19 001242410.1_39727001_2 - 2.5e-37 128.4 7.7 4e-37 127.8 7.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.4 001242410.1_39727001_2 - 6.2e-06 26.0 1.5 1.2e-05 25.1 1.5 1.4 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.7 001242410.1_39727001_2 - 0.00052 19.3 3.0 0.00052 19.3 3.0 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.7 001242410.1_39727001_2 - 0.00098 18.4 1.9 0.0016 17.7 1.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv PgaD PF13994.4 001242410.1_39727001_2 - 0.25 11.2 2.3 0.9 9.4 1.3 2.2 2 0 0 2 2 2 0 PgaD-like protein DUF3429 PF11911.6 001242410.1_39727001_2 - 1.9 8.7 6.8 0.93 9.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) SH3_9 PF14604.4 001280359.1_39725001_3 - 3.3e-32 110.0 2.1 8.8e-16 57.4 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.15 001280359.1_39725001_3 - 4.5e-29 99.8 0.1 7.1e-15 54.3 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.26 001280359.1_39725001_3 - 3.4e-26 90.5 0.7 1.8e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 SH3 domain Sharpin_PH PF16764.3 001280415.1_39724001_2 - 1.2e-42 144.4 0.0 4.9e-42 142.4 0.0 1.9 2 0 0 2 2 2 1 Sharpin PH domain zf-RanBP PF00641.16 001280415.1_39724001_2 - 3.8e-06 26.0 2.8 8e-06 24.9 2.8 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others ubiquitin PF00240.21 001280415.1_39724001_2 - 0.036 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family zf-H2C2_2 PF13465.4 001280349.1_39724001_3 - 3e-27 93.7 64.2 1.8e-07 31.1 1.0 9.6 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.24 001280349.1_39724001_3 - 2.1e-19 68.7 70.1 4.8e-05 23.4 3.3 9.6 10 0 0 10 10 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280349.1_39724001_3 - 1.1e-12 47.5 65.5 0.02 15.6 1.1 8.6 9 0 0 9 9 8 6 C2H2-type zinc finger KRAB PF01352.25 001280349.1_39724001_3 - 4e-11 42.3 0.0 7.3e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001280349.1_39724001_3 - 2.4e-05 24.0 42.5 0.039 13.8 0.6 8.0 7 0 0 7 7 7 3 C2H2-type zinc finger FYVE PF01363.19 001280349.1_39724001_3 - 0.002 18.1 0.4 0.002 18.1 0.4 4.7 1 1 1 3 3 2 2 FYVE zinc finger Zn-ribbon_8 PF09723.8 001280349.1_39724001_3 - 0.078 13.0 31.1 0.16 12.0 1.8 6.4 4 2 1 6 6 6 0 Zinc ribbon domain zf-met PF12874.5 001280349.1_39724001_3 - 0.23 11.8 0.2 0.23 11.8 0.2 7.8 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.3 001280349.1_39724001_3 - 0.27 11.9 0.1 0.27 11.9 0.1 5.0 4 1 2 6 6 5 0 zinc-ribbon family GAGA PF09237.9 001280349.1_39724001_3 - 0.63 9.8 6.8 0.71 9.6 1.9 3.0 1 1 1 2 2 2 0 GAGA factor ADK_lid PF05191.12 001280349.1_39724001_3 - 4 7.4 14.4 4.4 7.3 0.7 4.9 2 2 3 5 5 5 0 Adenylate kinase, active site lid DUF3268 PF11672.6 001280349.1_39724001_3 - 5 7.3 14.3 0.49 10.6 0.9 4.0 4 0 0 4 4 4 0 zinc-finger-containing domain zinc_ribbon_5 PF13719.4 001280349.1_39724001_3 - 8.2 6.2 28.9 0.043 13.5 2.0 5.3 4 2 0 4 4 3 0 zinc-ribbon domain 7tm_4 PF13853.4 001168365.1_39722001_1 - 1.5e-54 185.5 21.5 1.8e-54 185.3 21.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001168365.1_39722001_1 - 1.1e-25 90.3 27.3 2.7e-25 89.0 27.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001168365.1_39722001_1 - 6.5e-05 22.3 22.1 8.8e-05 21.9 22.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 001168365.1_39722001_1 - 0.00046 19.5 20.8 0.0006 19.1 20.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Pribosyltran_N PF13793.4 001280389.1_39726001_3 - 4.4e-46 155.4 0.3 8.7e-46 154.5 0.1 1.6 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.4 001280389.1_39726001_3 - 5.4e-43 147.1 3.5 2.9e-36 125.1 1.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.25 001280389.1_39726001_3 - 4.5e-14 52.1 0.9 1.1e-13 50.8 0.3 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.4 001280389.1_39726001_3 - 0.0013 18.1 0.2 0.002 17.5 0.2 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Arm PF00514.21 001280431.1_39724001_2 - 6.8e-76 248.2 21.6 1e-11 44.3 0.2 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.4 001280431.1_39724001_2 - 1.5e-25 89.0 8.1 4.8e-07 30.0 0.2 5.7 4 1 1 5 5 5 4 HEAT-like repeat IBB PF01749.18 001280431.1_39724001_2 - 1e-19 70.5 0.2 2.9e-19 69.1 0.2 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.3 001280431.1_39724001_2 - 4.2e-19 67.7 0.7 3.2e-18 64.9 1.1 2.2 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.4 001280431.1_39724001_2 - 8.2e-18 64.4 0.4 7.6e-05 22.9 0.0 5.4 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.20 001280431.1_39724001_2 - 3.4e-12 45.4 8.7 0.024 14.7 0.0 7.1 8 0 0 8 8 8 4 HEAT repeat Adaptin_N PF01602.18 001280431.1_39724001_2 - 1.4e-07 30.3 0.8 0.00066 18.2 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_PBS PF03130.14 001280431.1_39724001_2 - 2.8e-07 30.4 3.0 2.2 9.0 0.0 6.1 5 1 0 5 5 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.6 001280431.1_39724001_2 - 0.00023 21.1 0.6 2.1 8.3 0.0 4.5 5 1 1 6 6 6 2 V-ATPase subunit H V-ATPase_H_N PF03224.12 001280431.1_39724001_2 - 0.017 14.3 1.0 4.1 6.5 0.0 3.4 1 1 2 3 3 3 0 V-ATPase subunit H Sec7_N PF12783.5 001280431.1_39724001_2 - 0.017 14.9 0.8 3.8 7.3 0.1 3.1 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3385 PF11865.6 001280431.1_39724001_2 - 0.085 12.6 0.1 9.9 5.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) DUF3361 PF11841.6 001280431.1_39724001_2 - 1.8 8.4 4.8 66 3.3 0.1 4.2 3 3 1 5 5 5 0 Domain of unknown function (DUF3361) Fascin PF06268.11 001246474.1_39724001_1 - 1.3e-62 208.7 0.0 2.8e-28 98.2 0.0 4.5 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.10 001246474.1_39724001_1 - 1.5e-10 41.0 1.3 0.27 10.8 0.0 5.7 4 2 2 6 6 6 3 FRG1-like domain DUF569 PF04601.11 001246474.1_39724001_1 - 0.0042 16.6 0.0 0.17 11.5 0.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF569) FGF PF00167.16 001246474.1_39724001_1 - 0.015 15.2 3.0 0.058 13.4 0.0 3.1 5 0 0 5 5 5 0 Fibroblast growth factor AP3D1 PF06375.9 001246474.1_39724001_1 - 0.76 9.9 16.5 1.2 9.3 16.5 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 RNA_polI_A34 PF08208.9 001246474.1_39724001_1 - 6.9 6.6 22.6 12 5.9 22.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.7 001246474.1_39724001_2 - 0.011 15.5 17.8 0.016 15.0 17.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AP3D1 PF06375.9 001246474.1_39724001_2 - 0.52 10.4 18.1 0.7 10.0 18.1 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4604 PF15377.4 001246474.1_39724001_2 - 1 9.7 15.6 1.3 9.3 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RNA_polI_A34 PF08208.9 001246474.1_39724001_3 - 0.0054 16.7 17.8 0.0076 16.2 17.8 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.7 001246474.1_39724001_3 - 0.64 9.5 27.6 0.85 9.0 27.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med19 PF10278.7 001246474.1_39724001_3 - 0.68 9.7 20.8 0.93 9.3 20.8 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4604 PF15377.4 001246474.1_39724001_3 - 1.2 9.4 19.5 1.6 9.0 19.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) AP3D1 PF06375.9 001246474.1_39724001_3 - 4.3 7.5 21.3 5.8 7.0 21.3 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 AbLIM_anchor PF16182.3 001280326.1_39726001_1 - 1.8e-77 261.6 13.8 3.2e-57 194.9 9.3 2.2 1 1 1 2 2 2 2 Putative adherens-junction anchoring region of AbLIM VHP PF02209.17 001280326.1_39726001_1 - 9e-15 54.3 0.8 2.2e-14 53.1 0.8 1.7 1 0 0 1 1 1 1 Villin headpiece domain STAT1_TAZ2bind PF12162.6 001280326.1_39726001_1 - 0.048 13.1 0.8 6.5 6.3 0.0 2.7 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain Keratin_B2_2 PF13885.4 001195152.1_39723001_3 - 1.5e-17 63.1 220.9 1.6e-05 24.6 49.9 5.4 1 1 4 5 5 5 5 Keratin, high sulfur B2 protein Keratin_B2 PF01500.15 001195152.1_39723001_3 - 0.00095 19.1 162.5 0.76 9.6 42.6 3.9 1 1 0 2 2 2 2 Keratin, high sulfur B2 protein Bcl-2 PF00452.17 001246544.1_39724001_3 - 0.00013 22.4 0.0 0.00031 21.1 0.0 1.7 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family CF222 PF15661.3 001246544.1_39724001_3 - 0.0088 14.8 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 1 C6orf222, uncharacterised family Bromodomain PF00439.23 001280266.1_39727001_2 - 6.2e-41 138.2 6.8 1e-20 73.5 0.6 2.7 2 0 0 2 2 2 2 Bromodomain BET PF17035.3 001280266.1_39727001_2 - 5.5e-28 96.8 0.1 2.1e-27 95.0 0.1 2.1 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation BRD4_CDT PF17105.3 001280266.1_39727001_2 - 1.4e-22 78.9 5.3 4.4e-22 77.3 5.3 2.0 1 0 0 1 1 1 1 C-terminal domain of bromodomain protein 4 Pkinase_C PF00433.22 001280266.1_39727001_2 - 0.11 13.1 2.8 6.9 7.3 0.0 3.4 3 0 0 3 3 3 0 Protein kinase C terminal domain zf-H2C2_2 PF13465.4 001246598.2_39724001_1 - 2.7e-32 109.6 76.8 1.4e-08 34.7 1.3 10.4 11 0 0 11 11 11 5 Zinc-finger double domain zf-C2H2 PF00096.24 001246598.2_39724001_1 - 2.1e-23 81.3 66.0 9.6e-06 25.7 1.1 8.8 10 0 0 10 10 9 6 Zinc finger, C2H2 type KRAB PF01352.25 001246598.2_39724001_1 - 5.2e-21 73.9 0.4 9.5e-21 73.1 0.4 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001246598.2_39724001_1 - 2.6e-12 46.3 63.5 0.0033 18.0 0.8 9.0 10 0 0 10 10 8 6 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001246598.2_39724001_1 - 5.2e-06 26.2 31.5 0.011 15.5 0.8 6.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.5 001246598.2_39724001_1 - 0.00089 19.4 38.4 0.0082 16.4 0.6 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001246598.2_39724001_1 - 0.031 14.5 33.5 1.1 9.6 2.7 6.6 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001246598.2_39724001_1 - 0.2 11.7 27.0 0.14 12.2 4.0 4.9 4 1 2 6 6 6 0 Zinc ribbon domain DUF3268 PF11672.6 001246598.2_39724001_1 - 0.76 10.0 10.1 5.4 7.3 1.0 3.4 2 1 1 3 3 3 0 zinc-finger-containing domain zinc_ribbon_15 PF17032.3 001246598.2_39724001_1 - 0.98 10.1 20.0 1.7 9.3 1.5 4.5 2 1 2 4 4 4 0 zinc-ribbon family LIM PF00412.20 001246598.2_39724001_1 - 1.6 8.9 19.6 16 5.7 1.1 5.6 2 1 3 5 5 5 0 LIM domain DZR PF12773.5 001246598.2_39724001_1 - 2.2 8.2 19.5 4.1e+02 1.0 0.0 4.6 3 1 0 3 3 3 0 Double zinc ribbon zf-LYAR PF08790.9 001246598.2_39724001_1 - 3.7 7.4 21.8 1.5 8.7 1.6 5.7 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger GAGA PF09237.9 001246598.2_39724001_1 - 7.3 6.3 8.2 18 5.1 0.8 3.4 2 1 1 3 3 3 0 GAGA factor DUF3996 PF13161.4 001246598.2_39724001_2 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3996) Ras PF00071.20 001246596.2_39724001_3 - 1.7e-26 92.6 0.5 2.2e-26 92.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001246596.2_39724001_3 - 1.1e-10 41.6 0.0 1.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001246596.2_39724001_3 - 6.1e-09 35.4 0.4 8.9e-09 34.9 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.25 001246596.2_39724001_3 - 0.0013 18.2 0.5 0.11 11.9 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.21 001246596.2_39724001_3 - 0.0021 18.0 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.17 001246596.2_39724001_3 - 0.1 12.1 3.7 0.99 8.8 0.5 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L15e PF00827.15 001280001.1_39725001_2 - 1.6e-96 321.4 2.5 2.1e-96 321.0 2.5 1.1 1 0 0 1 1 1 1 Ribosomal L15 WH2 PF02205.18 001246480.1_39725001_2 - 1.5e-07 30.9 0.1 3.3e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 WH2 motif SAM_2 PF07647.15 001251908.1_39725001_2 - 1.9e-18 66.2 0.3 2.8e-18 65.6 0.3 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001251908.1_39725001_2 - 1.2e-07 31.9 0.1 2.1e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.14 001251908.1_39725001_2 - 4.5e-05 23.2 0.0 9.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain TMEM144 PF07857.10 001279788.1_39724001_3 - 2.2e-146 487.0 19.2 2.6e-146 486.8 19.2 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.10 001279788.1_39724001_3 - 5.5e-09 35.6 5.4 5.5e-09 35.6 5.4 2.3 2 0 0 2 2 2 2 Sugar transport protein AMPK1_CBM PF16561.3 001246601.1_39725001_1 - 7.3e-34 115.7 0.2 1.1e-33 115.1 0.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.13 001246601.1_39725001_1 - 4.9e-27 93.9 1.5 1e-26 92.8 1.5 1.6 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.16 001246601.1_39725001_1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) zf-H2C2_2 PF13465.4 001071785.1_39725001_1 - 1.5e-31 107.2 52.8 7.9e-09 35.4 1.2 7.8 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.24 001071785.1_39725001_1 - 2.5e-29 99.9 38.8 1.6e-06 28.1 3.1 6.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001071785.1_39725001_1 - 5.8e-20 70.1 34.0 0.00071 20.1 0.6 6.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001071785.1_39725001_1 - 2e-14 53.3 8.1 0.12 12.5 0.2 5.5 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001071785.1_39725001_1 - 2.2e-10 40.1 29.0 0.0016 18.2 0.4 6.0 5 1 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001071785.1_39725001_1 - 2.2e-08 33.9 16.4 0.0015 18.4 2.5 3.8 3 0 0 3 3 3 2 Zinc ribbon domain zinc_ribbon_9 PF14369.4 001071785.1_39725001_1 - 0.00038 20.5 14.3 0.84 9.8 0.2 5.6 5 0 0 5 5 5 2 zinc-ribbon zf-Di19 PF05605.10 001071785.1_39725001_1 - 0.00043 20.4 18.5 0.016 15.3 1.4 4.3 3 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.4 001071785.1_39725001_1 - 0.012 15.4 9.0 2.5 8.0 0.0 4.2 4 1 0 4 4 4 0 CpXC protein SprT-like PF10263.7 001071785.1_39725001_1 - 0.016 14.9 15.1 0.25 11.0 4.9 2.7 1 1 1 2 2 2 0 SprT-like family HTH_18 PF12833.5 001071785.1_39725001_1 - 0.027 14.6 2.9 23 5.2 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain C1_4 PF07975.10 001071785.1_39725001_1 - 0.034 14.3 8.7 1.3 9.2 0.4 3.6 2 1 0 3 3 3 0 TFIIH C1-like domain zf-LYAR PF08790.9 001071785.1_39725001_1 - 0.049 13.4 14.4 1.4 8.8 0.4 5.3 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-RING_7 PF02591.13 001071785.1_39725001_1 - 0.055 13.5 10.4 1.6 8.8 0.1 4.0 4 0 0 4 4 3 0 C4-type zinc ribbon domain zinc_ribbon_15 PF17032.3 001071785.1_39725001_1 - 0.089 13.4 10.2 3.9 8.2 3.6 3.2 1 1 1 2 2 2 0 zinc-ribbon family XPA_N PF01286.16 001071785.1_39725001_1 - 0.16 11.9 11.4 29 4.7 0.3 4.9 5 0 0 5 5 5 0 XPA protein N-terminal DUF2256 PF10013.7 001071785.1_39725001_1 - 0.23 11.5 10.1 12 6.0 0.0 5.5 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) FYDLN_acid PF09538.8 001071785.1_39725001_1 - 0.33 11.5 9.7 22 5.6 0.1 4.3 1 1 2 4 4 4 0 Protein of unknown function (FYDLN_acid) HypA PF01155.17 001071785.1_39725001_1 - 0.41 10.5 9.7 1.5 8.7 0.6 3.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.16 001071785.1_39725001_1 - 0.44 10.3 12.8 19 5.1 0.1 5.3 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) YhfH PF14149.4 001071785.1_39725001_1 - 0.46 10.4 10.5 36 4.3 0.0 5.1 5 0 0 5 5 5 0 YhfH-like protein DUF3268 PF11672.6 001071785.1_39725001_1 - 0.83 9.9 9.4 0.56 10.4 0.4 2.9 1 1 3 4 4 4 0 zinc-finger-containing domain FdhE PF04216.10 001071785.1_39725001_1 - 6.2 6.4 12.4 0.29 10.8 1.1 3.0 1 1 2 3 3 3 0 Protein involved in formate dehydrogenase formation zf-met PF12874.5 001071785.1_39725001_1 - 7.3 7.0 30.6 0.54 10.6 0.6 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type ADK_lid PF05191.12 001071785.1_39725001_1 - 8.1 6.4 14.1 21 5.1 0.1 4.0 2 1 0 2 2 2 0 Adenylate kinase, active site lid Pkinase PF00069.23 001280030.1_39725001_1 - 6.5e-10 38.7 0.0 1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain zinc_ribbon_2 PF13240.4 001280030.1_39725001_1 - 3.7e-07 29.5 4.3 8.1e-07 28.4 4.3 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Pkinase_Tyr PF07714.15 001280030.1_39725001_1 - 2.3e-06 27.0 0.0 3.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DZR PF12773.5 001280030.1_39725001_1 - 2.2e-05 24.2 0.3 6e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.3 001280030.1_39725001_1 - 0.00026 21.5 0.2 0.00069 20.2 0.2 1.7 1 0 0 1 1 1 1 zinc-ribbon family zf-ribbon_3 PF13248.4 001280030.1_39725001_1 - 0.00082 18.6 4.1 0.0013 17.9 2.9 2.1 2 0 0 2 2 2 1 zinc-ribbon domain UPF0547 PF10571.7 001280030.1_39725001_1 - 0.0012 18.8 2.4 0.0032 17.4 2.4 1.8 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 RNA_POL_M_15KD PF02150.14 001280030.1_39725001_1 - 0.016 14.9 3.2 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc-ribbons_6 PF07191.10 001280030.1_39725001_1 - 0.11 12.4 0.3 0.35 10.7 0.3 1.8 1 1 0 1 1 1 0 zinc-ribbons DUF2116 PF09889.7 001280030.1_39725001_1 - 0.12 12.3 1.2 0.88 9.5 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Nudix_N_2 PF14803.4 001280030.1_39725001_1 - 0.18 11.6 2.2 9.8 6.1 0.1 2.9 2 0 0 2 2 2 0 Nudix N-terminal zf-C3HC4_3 PF13920.4 001280030.1_39725001_1 - 0.48 10.2 2.2 0.8 9.5 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Yip1 PF04893.15 001246369.1_39723001_3 - 1.8e-09 37.4 21.9 3.7e-09 36.4 21.4 1.8 1 1 1 2 2 2 1 Yip1 domain FAM219A PF15260.4 001280229.1_39726001_2 - 2e-27 95.9 0.6 3.2e-27 95.3 0.6 1.3 1 0 0 1 1 1 1 Protein family FAM219A FAM219A PF15260.4 001280229.1_39726001_3 - 5.3e-23 81.6 7.2 8.5e-23 81.0 7.2 1.3 1 0 0 1 1 1 1 Protein family FAM219A GCV_H PF01597.17 001251912.2_39724001_2 - 1.2e-05 25.1 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein BTB PF00651.29 001246396.1_39725001_2 - 1.4e-13 50.9 0.0 4.2e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.13 001246396.1_39725001_2 - 2e-05 24.5 0.1 5.2e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch zf-H2C2_2 PF13465.4 001246558.1_39725001_1 - 9.7e-21 73.1 33.6 2.1e-07 30.9 0.6 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.24 001246558.1_39725001_1 - 4.8e-20 70.7 29.9 0.0001 22.4 1.2 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001246558.1_39725001_1 - 3.3e-11 42.9 30.7 0.0056 17.3 4.4 6.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001246558.1_39725001_1 - 0.00044 20.4 5.4 0.14 12.3 1.1 2.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.3 001246558.1_39725001_1 - 0.0006 19.4 14.0 0.79 9.4 2.1 3.6 3 0 0 3 3 3 3 zinc-finger C2H2-type zf-C2HC_2 PF13913.4 001246558.1_39725001_1 - 0.00085 19.0 5.5 0.43 10.4 0.0 4.4 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_aberr PF17017.3 001246558.1_39725001_1 - 0.0024 17.9 9.4 3.5 7.6 0.1 4.2 1 1 3 4 4 4 2 Aberrant zinc-finger zf-met PF12874.5 001246558.1_39725001_1 - 0.98 9.8 11.4 13 6.1 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001246558.1_39725001_1 - 1.4 9.2 8.0 18 5.7 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding RINGv PF12906.5 001280320.1_39725001_1 - 1.3e-15 57.1 7.2 2.7e-15 56.1 7.2 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.6 001280320.1_39725001_1 - 0.001 19.1 3.2 0.001 19.1 3.2 2.0 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.4 001280320.1_39725001_1 - 0.01 16.0 4.4 0.023 14.8 4.4 1.7 1 0 0 1 1 1 0 Ring finger domain SYF2 PF08231.10 001280375.1_39723001_2 - 4.5e-55 186.3 11.5 4.5e-55 186.3 11.5 1.8 2 0 0 2 2 2 1 SYF2 splicing factor tRNA_SAD PF07973.12 001280375.1_39723001_2 - 0.065 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain Thioredoxin_6 PF13848.4 001280427.1_39725001_2 - 5.2e-34 117.7 11.9 1.6e-30 106.3 4.4 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.18 001280427.1_39725001_2 - 5e-25 87.3 0.1 1.8e-15 56.6 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin OST3_OST6 PF04756.11 001280427.1_39725001_2 - 1.3e-05 24.6 2.9 0.36 10.0 0.0 3.2 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.4 001280427.1_39725001_2 - 0.0004 20.7 0.3 1.5 9.2 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001280427.1_39725001_2 - 0.00098 19.3 0.9 0.065 13.4 0.0 3.9 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.4 001280427.1_39725001_2 - 0.15 12.1 0.0 7.7 6.7 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin-like zf-CCHC PF00098.21 001280275.1_39724001_3 - 2.4e-47 156.8 63.3 3e-07 30.1 2.3 7.6 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.4 001280275.1_39724001_3 - 9.8e-12 44.3 48.7 0.0066 16.0 0.2 7.3 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.4 001280275.1_39724001_3 - 4.6e-10 38.9 54.6 0.0015 18.1 1.7 7.8 5 2 3 8 8 8 6 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.4 001280275.1_39724001_3 - 2.3e-05 24.1 46.3 0.011 15.6 0.2 7.2 2 1 5 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.4 001280275.1_39724001_3 - 0.019 14.6 1.2 0.019 14.6 1.2 7.2 7 0 0 7 7 7 0 Zinc knuckle RAWUL PF16207.3 001302437.1_39724001_1 - 4.2e-16 59.2 0.4 1e-15 58.0 0.4 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.4 001302437.1_39724001_1 - 2.2e-11 43.3 8.1 4.8e-11 42.2 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001302437.1_39724001_1 - 9.3e-09 34.9 9.0 9.3e-09 34.9 9.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001302437.1_39724001_1 - 3.8e-07 30.1 8.0 3.8e-07 30.1 8.0 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.4 001302437.1_39724001_1 - 1e-05 25.1 8.2 1e-05 25.1 8.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001302437.1_39724001_1 - 2.9e-05 23.8 9.0 2.9e-05 23.8 9.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.5 001302437.1_39724001_1 - 0.00019 21.5 5.0 0.00019 21.5 5.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.4 001302437.1_39724001_1 - 0.00035 20.4 5.3 0.00035 20.4 5.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.4 001302437.1_39724001_1 - 0.0007 19.6 8.8 0.0007 19.6 8.8 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF3337 PF11816.6 001302437.1_39724001_1 - 0.042 13.5 0.4 0.093 12.4 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3337) zf-Nse PF11789.6 001302437.1_39724001_1 - 0.058 13.1 3.3 0.11 12.3 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.4 001302437.1_39724001_1 - 0.072 12.7 9.9 0.026 14.1 5.9 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.3 001302437.1_39724001_1 - 0.65 10.0 10.3 0.15 12.1 5.8 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.4 001302437.1_39724001_1 - 0.7 9.7 15.7 0.094 12.5 9.8 2.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DZR PF12773.5 001302437.1_39724001_1 - 9.7 6.2 10.0 4.1 7.4 5.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon GST_N_3 PF13417.4 001246557.2_39724001_2 - 6.5e-20 71.2 0.0 1.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001246557.2_39724001_2 - 2.6e-15 56.3 0.0 5.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.18 001246557.2_39724001_2 - 2e-14 53.5 0.0 3.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001246557.2_39724001_2 - 1.4e-09 37.9 0.1 4.9e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001246557.2_39724001_2 - 2.3e-07 30.5 0.0 1.1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001246557.2_39724001_2 - 7.2e-07 29.2 0.1 1.3e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.22 001246557.2_39724001_2 - 0.0054 16.8 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin PPR_2 PF13041.4 001280214.1_39726001_1 - 6.4e-23 80.6 1.1 3.3e-09 36.7 0.2 5.5 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.4 001280214.1_39726001_1 - 3.1e-13 49.4 2.3 2.1e-06 27.6 0.3 4.5 6 1 0 6 6 6 2 Pentatricopeptide repeat domain PPR_long PF17177.2 001280214.1_39726001_1 - 7.1e-08 31.9 0.1 3.3e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PROPR PPR_1 PF12854.5 001280214.1_39726001_1 - 2.7e-05 23.7 0.1 3.9 7.1 0.0 5.6 6 0 0 6 6 6 2 PPR repeat RPM2 PF08579.9 001280214.1_39726001_1 - 0.003 17.8 1.6 0.0047 17.1 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) PPR PF01535.18 001280214.1_39726001_1 - 0.005 16.9 12.0 0.053 13.6 0.1 6.5 9 0 0 9 9 9 1 PPR repeat FANCI_S2 PF14676.4 001280214.1_39726001_1 - 0.055 13.6 0.6 0.2 11.8 0.3 2.0 2 0 0 2 2 2 0 FANCI solenoid 2 AF-4 PF05110.11 001280214.1_39726001_1 - 2.4 6.0 4.6 3.1 5.7 4.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CD225 PF04505.10 001198758.1_39722001_3 - 5e-32 109.7 1.5 8.4e-32 109.0 1.5 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Phage_holin_2_3 PF16080.3 001198758.1_39722001_3 - 0.12 12.0 1.5 0.37 10.5 1.5 1.9 1 0 0 1 1 1 0 Bacteriophage holin family HP1 ABC_tran PF00005.25 001246609.1_39725001_1 - 1.9e-37 128.7 0.0 1.6e-18 67.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.13 001246609.1_39725001_1 - 1.8e-14 53.1 7.2 5.3e-14 51.6 7.2 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.4 001246609.1_39725001_1 - 3e-10 40.3 1.6 0.22 11.1 0.8 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.17 001246609.1_39725001_1 - 6.1e-10 38.8 2.4 0.0054 16.0 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.25 001246609.1_39725001_1 - 1.4e-07 30.9 1.6 1.4e-07 30.9 1.6 3.2 4 0 0 4 4 3 1 4Fe-4S binding domain AAA_16 PF13191.4 001246609.1_39725001_1 - 2.1e-05 24.9 0.0 0.054 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.27 001246609.1_39725001_1 - 4.1e-05 23.9 0.0 0.041 14.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.5 001246609.1_39725001_1 - 5.9e-05 22.9 0.9 5.9e-05 22.9 0.9 3.1 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.4 001246609.1_39725001_1 - 7e-05 22.5 0.0 0.39 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.4 001246609.1_39725001_1 - 7.3e-05 22.3 0.1 0.28 10.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.14 001246609.1_39725001_1 - 7.4e-05 22.6 0.0 0.16 11.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.4 001246609.1_39725001_1 - 0.0001 22.5 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.10 001246609.1_39725001_1 - 0.00038 20.3 0.4 0.044 13.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fer4_21 PF14697.4 001246609.1_39725001_1 - 0.0025 17.8 11.2 0.0093 16.0 11.2 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.20 001246609.1_39725001_1 - 0.0027 17.2 1.7 0.22 11.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.4 001246609.1_39725001_1 - 0.0034 17.0 0.2 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.5 001246609.1_39725001_1 - 0.0039 17.1 0.7 0.0039 17.1 0.7 3.0 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_24 PF13479.4 001246609.1_39725001_1 - 0.0042 16.7 0.2 0.69 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.4 001246609.1_39725001_1 - 0.0048 16.9 0.0 0.77 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.20 001246609.1_39725001_1 - 0.0066 16.7 0.0 3.3 8.0 0.0 3.2 3 0 0 3 3 3 1 RNA helicase Fer4_7 PF12838.5 001246609.1_39725001_1 - 0.0072 16.8 1.0 0.0072 16.8 1.0 3.3 2 1 2 4 4 4 1 4Fe-4S dicluster domain Fer4_10 PF13237.4 001246609.1_39725001_1 - 0.012 15.6 1.7 0.012 15.6 1.7 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain TsaE PF02367.15 001246609.1_39725001_1 - 0.02 14.8 0.2 0.23 11.3 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.4 001246609.1_39725001_1 - 0.026 14.6 0.2 6.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.4 001246609.1_39725001_1 - 0.034 14.9 0.9 0.034 14.9 0.9 3.1 4 0 0 4 4 2 0 4Fe-4S double cluster binding domain AAA_18 PF13238.4 001246609.1_39725001_1 - 0.048 14.0 0.0 9.7 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.4 001246609.1_39725001_1 - 0.05 14.0 5.4 0.23 11.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.13 001246609.1_39725001_1 - 0.074 11.8 0.0 3.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.12 001246609.1_39725001_1 - 0.17 11.8 1.1 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.21 001246609.1_39725001_1 - 0.19 11.7 0.9 23 5.0 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.4 001246609.1_39725001_1 - 0.19 11.6 0.9 39 4.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain Fer4_4 PF12800.5 001246609.1_39725001_1 - 2 9.0 13.4 0.56 10.7 2.2 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.4 001246609.1_39725001_1 - 6.7 6.8 21.1 0.035 14.1 11.8 2.1 2 0 0 2 2 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.4 001246609.1_39725001_1 - 9.9 6.7 12.1 0.19 12.1 1.4 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain LRR_4 PF12799.5 001246504.1_39724001_3 - 4.1e-08 33.2 5.4 0.00035 20.7 0.4 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001246504.1_39724001_3 - 6.5e-07 28.9 4.0 3.5e-05 23.3 2.8 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.4 001246504.1_39724001_3 - 3.1e-06 26.7 0.0 4.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.31 001246504.1_39724001_3 - 0.13 12.7 0.7 46 4.9 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat RRN9 PF10680.7 001246504.1_39724001_3 - 3.1 8.0 4.7 0.85 9.8 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RPAP3_C PF13877.4 001280093.1_39724001_3 - 1.1e-12 48.1 0.0 2.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Dynein_attach_N PF15867.3 001280093.1_39724001_3 - 3.4e-12 46.0 2.0 3.5e-05 23.5 0.9 2.5 1 1 1 2 2 2 2 Dynein attachment factor N-terminus EMP70 PF02990.14 001280363.1_39725001_3 - 4.3e-207 688.7 13.8 6e-207 688.2 13.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3817 PF12823.5 001280363.1_39725001_3 - 0.14 12.9 0.1 0.14 12.9 0.1 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF3817) DUF4229 PF14012.4 001280363.1_39725001_3 - 1.9 8.5 0.0 1.9 8.5 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF4229) zf-H2C2_2 PF13465.4 001279993.1_39724001_3 - 1.7e-71 233.5 102.3 1.9e-08 34.2 3.6 12.2 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2 PF00096.24 001279993.1_39724001_3 - 2.6e-50 166.0 112.6 9.3e-06 25.7 0.2 12.5 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001279993.1_39724001_3 - 3.6e-26 89.5 114.0 0.0011 19.4 0.3 12.6 12 1 1 13 13 12 11 C2H2-type zinc finger KRAB PF01352.25 001279993.1_39724001_3 - 3.4e-23 80.9 0.3 6.1e-23 80.1 0.3 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001279993.1_39724001_3 - 2.6e-19 68.6 98.1 5.3e-05 22.9 2.7 12.9 12 2 0 12 12 12 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001279993.1_39724001_3 - 0.00012 22.2 81.1 0.028 14.6 0.7 11.6 12 0 0 12 12 11 6 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001279993.1_39724001_3 - 0.00067 19.6 81.6 0.18 11.8 5.7 10.3 3 3 10 13 13 13 8 Zinc ribbon domain XPA_N PF01286.16 001279993.1_39724001_3 - 0.057 13.3 61.0 2.8 7.9 0.1 12.1 12 0 0 12 12 12 0 XPA protein N-terminal zinc_ribbon_15 PF17032.3 001279993.1_39724001_3 - 0.087 13.5 72.9 0.09 13.4 4.7 7.0 1 1 6 7 7 7 0 zinc-ribbon family Fanconi_A PF03511.12 001279993.1_39724001_3 - 0.096 12.5 0.6 1.7 8.5 0.1 2.8 2 0 0 2 2 2 0 Fanconi anaemia group A protein Ribosomal_L17 PF01196.17 001279993.1_39724001_3 - 0.26 12.1 6.0 0.34 11.7 0.3 3.7 4 2 1 5 5 5 0 Ribosomal protein L17 Scramblase PF03803.13 001279993.1_39724001_3 - 4.1 6.5 11.0 1.2 8.3 5.2 2.3 2 0 0 2 2 2 0 Scramblase TPR_1 PF00515.26 001246399.1_39725001_3 - 4.4e-26 89.4 10.2 5.1e-08 32.3 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.15 001246399.1_39725001_3 - 1.4e-21 74.7 9.7 2.5e-05 23.9 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.4 001246399.1_39725001_3 - 2.1e-10 40.6 5.6 0.019 15.1 0.6 5.3 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.4 001246399.1_39725001_3 - 1.1e-09 37.6 9.0 0.0056 16.2 0.2 4.5 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.4 001246399.1_39725001_3 - 2.1e-07 30.5 11.2 0.018 15.1 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.4 001246399.1_39725001_3 - 2e-05 25.1 0.5 0.043 14.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001246399.1_39725001_3 - 2e-05 24.4 3.6 0.00035 20.4 0.2 3.1 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.4 001246399.1_39725001_3 - 8.9e-05 22.8 1.0 0.025 14.9 0.2 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001246399.1_39725001_3 - 0.00014 21.9 12.0 0.021 14.9 5.7 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.4 001246399.1_39725001_3 - 0.00033 20.7 4.9 0.3 11.4 0.1 4.8 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_14 PF13428.4 001246399.1_39725001_3 - 0.0014 19.1 1.6 19 6.2 0.1 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.4 001246399.1_39725001_3 - 0.024 14.7 0.8 29 4.8 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.4 001246399.1_39725001_3 - 0.028 14.2 4.8 1.3 8.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.16 001246399.1_39725001_3 - 0.042 13.8 9.3 6.7 6.7 0.1 5.0 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain PknG_TPR PF16918.3 001246399.1_39725001_3 - 0.043 12.4 0.0 0.075 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat DUF4919 PF16266.3 001246399.1_39725001_3 - 0.06 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_7 PF13176.4 001246399.1_39725001_3 - 0.061 13.3 6.0 32 4.7 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.15 001246399.1_39725001_3 - 0.23 11.8 0.9 43 4.4 0.1 3.0 2 1 0 2 2 2 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.7 001246399.1_39725001_3 - 0.31 10.4 5.0 5.1 6.5 0.1 4.5 6 0 0 6 6 5 0 SHNi-TPR TPR_6 PF13174.4 001246399.1_39725001_3 - 1.5 9.5 7.0 1.1e+02 3.7 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-DHHC PF01529.18 001280180.1_39724001_3 - 6.1e-34 116.9 13.1 6.1e-34 116.9 13.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase PLDc_2 PF13091.4 001279852.1_39725001_3 - 1.2e-10 41.3 0.0 0.00014 21.7 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.20 001279852.1_39725001_3 - 0.013 15.5 0.1 0.89 9.7 0.1 2.7 2 0 0 2 2 2 0 Phospholipase D Active site motif Occludin_ELL PF07303.11 001246499.1_39725001_2 - 6.6e-29 100.5 7.5 1e-28 99.9 7.5 1.3 1 0 0 1 1 1 1 Occludin homology domain ELL PF10390.7 001246499.1_39725001_2 - 6.1e-12 45.5 0.0 1.6e-11 44.1 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL BicD PF09730.7 001246499.1_39725001_2 - 0.028 12.8 1.2 0.04 12.2 1.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D zf-C2H2 PF00096.24 001280340.1_39726001_3 - 0.066 13.6 14.9 3.5 8.1 0.3 4.4 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280340.1_39726001_3 - 0.55 11.1 14.3 1.6 9.7 0.5 4.2 3 1 2 5 5 5 0 C2H2-type zinc finger AT_hook PF02178.17 001246496.1_39724001_3 - 7.5 6.7 38.0 7.1 6.7 9.1 4.2 3 0 0 3 3 3 0 AT hook motif zf-H2C2_2 PF13465.4 001246395.1_39724001_2 - 6.6e-30 102.1 42.3 5.9e-08 32.7 0.6 6.7 6 0 0 6 6 6 5 Zinc-finger double domain SCAN PF02023.15 001246395.1_39724001_2 - 1e-25 89.2 0.3 2e-25 88.3 0.3 1.5 1 0 0 1 1 1 1 SCAN domain zf-C2H2 PF00096.24 001246395.1_39724001_2 - 1.9e-17 62.5 44.3 3e-05 24.1 1.3 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001246395.1_39724001_2 - 1.3e-14 53.5 41.0 0.0013 19.2 1.9 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001246395.1_39724001_2 - 3.4e-06 26.7 40.0 0.02 14.7 0.5 6.3 5 2 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.5 001246395.1_39724001_2 - 7.4e-06 26.1 38.1 0.0031 17.7 6.0 5.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type BolA PF01722.16 001246395.1_39724001_2 - 0.12 12.5 1.5 5.3 7.3 0.1 3.0 2 1 0 2 2 2 0 BolA-like protein zf-C2H2_11 PF16622.3 001246395.1_39724001_2 - 0.12 12.0 0.1 0.12 12.0 0.1 3.9 4 0 0 4 4 3 0 zinc-finger C2H2-type YchF-GTPase_C PF06071.11 001246395.1_39724001_2 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF933) zf-AN1 PF01428.14 001246395.1_39724001_2 - 1 9.4 24.8 2.7 8.1 2.0 5.5 4 1 1 5 5 5 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.8 001246395.1_39724001_2 - 1.8 8.6 23.1 0.27 11.2 2.5 4.6 3 2 2 5 5 5 0 Zinc ribbon domain C1_4 PF07975.10 001246395.1_39724001_2 - 2.5 8.3 18.1 29 4.9 4.3 4.2 2 1 2 4 4 4 0 TFIIH C1-like domain Ta0938 PF11494.6 001246395.1_39724001_2 - 4.8 7.4 6.1 5.4 7.2 0.2 3.1 1 1 2 3 3 3 0 Ta0938 DLIC PF05783.9 001280462.1_39724001_1 - 1.2e-255 848.6 0.0 1.5e-255 848.2 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ABC_tran PF00005.25 001280462.1_39724001_1 - 7e-05 23.2 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Roc PF08477.11 001280462.1_39724001_1 - 0.0007 19.7 0.1 0.0022 18.1 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF258 PF03193.14 001280462.1_39724001_1 - 0.0036 17.1 0.2 0.24 11.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.4 001280462.1_39724001_1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.7 001280462.1_39724001_1 - 0.013 15.1 0.1 0.041 13.5 0.1 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.20 001280462.1_39724001_1 - 0.038 13.5 0.2 6.2 6.3 0.0 2.5 2 1 0 2 2 2 0 Ras family DUF815 PF05673.11 001280462.1_39724001_1 - 0.039 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.18 001280462.1_39724001_1 - 0.048 12.7 0.2 0.11 11.5 0.2 1.6 1 1 0 1 1 1 0 G-protein alpha subunit Adap_comp_sub PF00928.19 001246384.1_39725001_3 - 4.7e-92 308.0 0.4 4.7e-92 308.0 0.4 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.18 001246384.1_39725001_3 - 0.00012 21.9 0.9 0.0002 21.2 0.9 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fer4 PF00037.25 001246384.1_39725001_3 - 0.039 13.6 4.2 0.087 12.5 4.2 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Thioredoxin PF00085.18 001246647.1_39724001_1 - 2.9e-63 210.2 0.0 1.9e-30 104.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.4 001246647.1_39724001_1 - 1.8e-10 41.1 0.1 0.00039 20.7 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.4 001246647.1_39724001_1 - 2.6e-09 37.2 0.0 2e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.4 001246647.1_39724001_1 - 1.2e-07 31.6 0.0 0.0024 17.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.11 001246647.1_39724001_1 - 2.7e-07 30.1 0.0 0.00039 19.7 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.4 001246647.1_39724001_1 - 1e-06 28.8 0.0 0.072 13.3 0.0 3.8 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.19 001246647.1_39724001_1 - 0.0016 18.2 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_3 PF13192.4 001246647.1_39724001_1 - 0.0031 17.4 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.4 001246647.1_39724001_1 - 0.051 13.2 0.0 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.4 001246647.1_39724001_1 - 0.056 13.5 0.2 2.9 7.9 0.0 2.9 2 1 1 3 3 3 0 Thioredoxin HyaE PF07449.9 001246647.1_39724001_1 - 0.086 12.7 0.0 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE L51_S25_CI-B8 PF05047.14 001251923.1_39729001_3 - 8.1e-10 38.3 0.2 1.5e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zf-C2H2_4 PF13894.4 001302408.1_39724001_2 - 0.43 11.4 7.1 4.2 8.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.12 001302408.1_39724001_2 - 1.1 9.2 3.8 0.65 9.9 1.3 2.0 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif SOG2 PF10428.7 001302408.1_39724001_2 - 7 5.6 12.2 9.7 5.2 12.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3699 PF12480.6 001328285.1_39725001_2 - 2.1e-30 104.5 0.5 3.7e-30 103.7 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3699) HSP90 PF00183.16 001280500.1_39725001_2 - 1.5e-100 337.4 3.3 9.2e-96 321.6 0.8 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.4 001280500.1_39725001_2 - 1.4e-11 44.3 0.0 3.9e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.24 001280500.1_39725001_2 - 4.2e-09 36.8 0.1 7.3e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-C2HC_2 PF13913.4 001280401.1_39725001_2 - 8.6e-28 95.5 18.7 5.4e-08 32.4 1.4 4.7 4 0 0 4 4 4 4 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.12 001280401.1_39725001_2 - 0.012 15.3 2.4 1.5 8.6 0.0 3.8 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-C2H2 PF00096.24 001280401.1_39725001_2 - 0.031 14.6 13.4 6.1 7.4 1.4 5.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280401.1_39725001_2 - 0.49 11.2 23.6 3 8.8 0.7 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger zf-RING_7 PF02591.13 001280401.1_39725001_2 - 0.67 10.1 6.5 11 6.1 0.0 3.6 3 0 0 3 3 3 0 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.4 001280401.1_39725001_2 - 4.8 7.1 14.1 5.1 7.0 0.1 5.2 6 0 0 6 6 6 0 zinc-ribbon domain c-SKI_SMAD_bind PF08782.8 001280401.1_39725001_2 - 5.2 7.3 11.8 1.6 8.9 0.1 3.5 4 0 0 4 4 4 0 c-SKI Smad4 binding domain Serinc PF03348.13 001280388.1_39724001_3 - 1.4e-170 567.8 15.7 1.6e-170 567.5 15.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) CBFD_NFYB_HMF PF00808.21 001246516.1_39725001_2 - 1.6e-12 47.4 0.1 3e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.4 001246516.1_39725001_2 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.22 001246516.1_39725001_2 - 0.01 16.1 0.0 0.01 16.1 0.0 2.2 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Afi1 PF07792.10 001246516.1_39725001_2 - 0.037 14.4 5.7 0.07 13.5 5.7 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking BUD22 PF09073.8 001246516.1_39725001_2 - 0.088 12.0 15.5 0.12 11.5 15.5 1.1 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.3 001246516.1_39725001_2 - 0.26 10.5 11.1 0.39 10.0 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Mtc1 PF10310.7 001246516.1_39725001_2 - 0.48 9.2 13.8 0.67 8.7 13.8 1.0 1 0 0 1 1 1 0 Maintenance of telomere capping protein 1 Vfa1 PF08432.8 001246516.1_39725001_2 - 2.1 8.5 16.3 3.1 8.0 16.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.9 001246516.1_39725001_2 - 2.9 7.2 17.8 4.2 6.6 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.12 001246516.1_39725001_2 - 4.7 6.8 15.4 7 6.3 15.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Rpn3_C PF08375.9 001246642.1_39725001_1 - 3.8e-28 97.6 3.0 3.8e-28 97.6 3.0 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.25 001246642.1_39725001_1 - 1.9e-24 86.0 0.0 5.5e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain TSKS PF15358.4 001246642.1_39725001_1 - 0.044 12.0 0.4 0.089 11.0 0.4 1.4 1 0 0 1 1 1 0 Testis-specific serine kinase substrate CSN8_PSD8_EIF3K PF10075.7 001246642.1_39725001_1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_2 PF07719.15 001246642.1_39725001_1 - 0.18 11.8 1.1 0.77 9.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.4 001246642.1_39725001_1 - 0.38 11.2 6.1 7.3 7.1 0.1 4.0 4 1 2 6 6 6 0 Tetratricopeptide repeat Ras PF00071.20 001242595.1_39723001_3 - 1.6e-21 76.5 0.1 2.2e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Fucokinase PF07959.10 001204796.1_39723001_3 - 4.5e-47 160.8 1.8 1.7e-37 129.3 0.5 2.1 1 1 1 2 2 2 2 L-fucokinase Hexapep PF00132.22 001204796.1_39723001_3 - 0.0053 16.3 1.6 0.023 14.3 0.3 2.5 2 1 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) UPF0715 PF17094.3 001204796.1_39723001_3 - 0.017 15.6 0.2 0.082 13.3 0.0 2.0 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0715) APOBEC_N PF08210.9 001345966.1_39724001_1 - 1.3e-101 337.7 14.1 2.3e-54 183.9 3.4 2.0 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001345966.1_39724001_1 - 6.5e-64 211.7 3.1 9.1e-32 108.7 0.1 2.5 2 0 0 2 2 2 2 APOBEC-like C-terminal domain Toxin-deaminase PF14424.4 001345966.1_39724001_1 - 0.00011 22.2 0.1 0.19 11.7 0.0 2.2 2 0 0 2 2 2 2 The BURPS668_1122 family of deaminases dCMP_cyt_deam_1 PF00383.21 001345966.1_39724001_1 - 0.00039 20.1 0.7 0.047 13.5 0.2 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Hairy_orange PF07527.11 001345966.1_39724001_1 - 0.0021 18.1 0.1 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 Hairy Orange DUF2947 PF11163.6 001345966.1_39724001_1 - 0.49 10.1 4.2 0.72 9.5 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2947) CAP_N PF01213.17 001246502.2_39724001_2 - 6.9 5.9 6.9 9.9 5.4 6.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRKCSH PF07915.11 001246502.2_39724001_3 - 1.7e-44 150.6 17.6 5.7e-26 91.2 7.1 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.4 001246502.2_39724001_3 - 2.1e-09 37.1 5.5 0.00046 19.8 0.4 2.4 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein AAA PF00004.27 001280481.1_39727001_1 - 3e-96 318.8 0.0 6.8e-47 159.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.16 001280481.1_39727001_1 - 2.1e-21 75.8 0.3 7.6e-21 74.0 0.3 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.10 001280481.1_39727001_1 - 4.7e-13 48.8 0.0 2.4e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.4 001280481.1_39727001_1 - 9.8e-13 48.7 4.7 5.3e-05 23.5 0.1 4.7 4 2 1 5 5 4 2 AAA ATPase domain CDC48_2 PF02933.15 001280481.1_39727001_1 - 2e-10 40.2 0.0 3.9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.4 001280481.1_39727001_1 - 2.4e-10 40.6 0.0 8.4e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.12 001280481.1_39727001_1 - 3.4e-10 40.2 0.0 5.3e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001280481.1_39727001_1 - 4.3e-10 39.6 0.1 6.7e-05 22.8 0.0 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.4 001280481.1_39727001_1 - 6.6e-09 36.0 0.9 0.019 15.1 0.1 4.0 3 2 1 4 4 2 2 AAA domain Vps4_C PF09336.8 001280481.1_39727001_1 - 1.7e-08 34.2 1.0 4.4e-05 23.3 0.1 2.6 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TIP49 PF06068.11 001280481.1_39727001_1 - 1.8e-08 33.6 0.0 0.0015 17.5 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.4 001280481.1_39727001_1 - 3.5e-07 30.7 0.0 0.03 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.20 001280481.1_39727001_1 - 4.4e-07 30.1 0.0 0.0087 16.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.19 001280481.1_39727001_1 - 6.3e-07 28.8 0.1 0.025 13.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.15 001280481.1_39727001_1 - 7.3e-07 29.0 0.1 0.054 13.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.4 001280481.1_39727001_1 - 1.1e-06 28.6 0.0 0.033 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.15 001280481.1_39727001_1 - 6.2e-06 25.4 0.1 0.045 12.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.4 001280481.1_39727001_1 - 1.1e-05 25.6 0.0 0.25 11.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.4 001280481.1_39727001_1 - 1.2e-05 24.8 0.5 2.1 7.7 0.0 3.6 2 1 0 3 3 3 1 AAA domain ATPase PF06745.11 001280481.1_39727001_1 - 1.7e-05 24.2 0.1 0.62 9.2 0.0 3.3 3 0 0 3 3 3 2 KaiC ATPase_2 PF01637.16 001280481.1_39727001_1 - 2e-05 24.5 0.2 0.32 10.7 0.0 3.6 2 2 1 3 3 2 2 ATPase domain predominantly from Archaea Bac_DnaA PF00308.16 001280481.1_39727001_1 - 2.3e-05 24.2 0.0 0.12 12.0 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein ABC_tran PF00005.25 001280481.1_39727001_1 - 2.4e-05 24.7 0.1 0.014 15.7 0.0 3.3 2 1 0 2 2 2 1 ABC transporter DUF815 PF05673.11 001280481.1_39727001_1 - 3.2e-05 23.1 0.0 0.017 14.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.4 001280481.1_39727001_1 - 9.3e-05 22.1 0.1 0.11 12.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain TsaE PF02367.15 001280481.1_39727001_1 - 0.00013 21.8 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.16 001280481.1_39727001_1 - 0.00015 21.4 0.0 0.0025 17.5 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.24 001280481.1_39727001_1 - 0.00023 20.8 0.0 0.59 9.7 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.4 001280481.1_39727001_1 - 0.00023 21.5 0.1 1.4 9.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain NACHT PF05729.10 001280481.1_39727001_1 - 0.00033 20.5 0.1 0.4 10.4 0.0 3.4 3 1 1 4 4 4 1 NACHT domain Zeta_toxin PF06414.10 001280481.1_39727001_1 - 0.0011 18.2 0.0 0.55 9.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.20 001280481.1_39727001_1 - 0.0012 17.8 0.0 0.31 9.9 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.7 001280481.1_39727001_1 - 0.0015 17.7 0.0 0.53 9.3 0.0 2.5 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.9 001280481.1_39727001_1 - 0.0015 18.2 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.13 001280481.1_39727001_1 - 0.0015 18.4 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.14 001280481.1_39727001_1 - 0.0024 17.2 0.5 2.3 7.5 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.4 001280481.1_39727001_1 - 0.0029 17.6 0.0 3.4 7.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.9 001280481.1_39727001_1 - 0.0042 16.2 0.2 13 4.8 0.1 4.2 4 0 0 4 4 4 0 Bacterial TniB protein AAA_11 PF13086.4 001280481.1_39727001_1 - 0.0051 16.4 0.0 2.9 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.4 001280481.1_39727001_1 - 0.0057 16.9 0.5 3.6 7.8 0.2 3.0 2 1 1 3 3 2 0 AAA domain AAA_30 PF13604.4 001280481.1_39727001_1 - 0.038 13.6 0.4 3.9 7.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain SKI PF01202.20 001280481.1_39727001_1 - 0.065 13.2 0.0 7.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.13 001280481.1_39727001_1 - 0.08 12.7 0.2 6.9 6.4 0.0 2.9 3 0 0 3 3 2 0 NTPase Cytidylate_kin PF02224.16 001280481.1_39727001_1 - 0.094 12.3 0.0 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase DUF3944 PF13099.4 001280481.1_39727001_1 - 0.13 12.0 0.0 0.41 10.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) HIG_1_N PF04588.11 001329986.1_39724001_2 - 2.9e-16 59.3 1.2 5.2e-16 58.5 1.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MFS_1 PF07690.14 001280273.1_39725001_2 - 1.2e-39 136.1 38.2 1.6e-34 119.3 24.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.8 001280273.1_39725001_2 - 0.2 11.3 6.6 0.057 13.0 0.4 2.6 2 1 1 3 3 3 0 Probable cobalt transporter subunit (CbtA) Aminotran_1_2 PF00155.19 001280503.1_39724001_3 - 1.4e-55 188.8 0.0 1.7e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.18 001280503.1_39724001_3 - 0.00055 18.4 0.0 0.0028 16.1 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.15 001280503.1_39724001_3 - 0.017 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.19 001280503.1_39724001_3 - 0.096 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.17 001280503.1_39724001_3 - 0.15 10.8 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V GSHPx PF00255.17 001115134.1_39723001_2 - 5e-40 135.3 0.1 6.9e-40 134.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase LysM PF01476.18 001115134.1_39723001_2 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 LysM domain DUF4782 PF16016.3 001280062.1_39725001_3 - 1.2e-34 119.8 0.8 2.3e-34 118.9 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4782) GRAM PF02893.18 001280062.1_39725001_3 - 9.3e-26 89.8 0.1 1.8e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 GRAM domain TarH PF02203.13 001280062.1_39725001_3 - 0.0067 16.2 1.6 0.012 15.4 1.6 1.3 1 0 0 1 1 1 1 Tar ligand binding domain homologue DUF4446 PF14584.4 001280062.1_39725001_3 - 0.05 13.4 1.8 0.12 12.2 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DASH_Hsk3 PF08227.9 001246460.1_39724001_3 - 1.2e-09 38.2 0.4 2.8e-09 37.0 0.4 1.7 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF2570 PF10828.6 001246460.1_39724001_3 - 5.1 6.9 7.4 6.5 6.5 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) TPR_2 PF07719.15 001280148.1_39725001_3 - 3.6e-30 101.5 8.0 0.0011 18.7 0.3 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.26 001280148.1_39725001_3 - 7.3e-27 91.9 10.6 0.00011 21.8 0.1 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.4 001280148.1_39725001_3 - 4.2e-19 68.5 10.8 2.5e-06 27.5 0.7 6.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.4 001280148.1_39725001_3 - 5.7e-19 66.6 5.9 0.0028 17.6 0.1 6.2 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_14 PF13428.4 001280148.1_39725001_3 - 1.5e-18 65.7 7.9 0.028 15.1 0.0 8.6 5 2 4 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.4 001280148.1_39725001_3 - 4.3e-15 54.4 11.4 0.0016 18.2 0.1 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.4 001280148.1_39725001_3 - 2.1e-12 47.3 11.2 0.005 17.2 0.0 5.9 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.4 001280148.1_39725001_3 - 8.1e-11 42.3 5.1 0.0026 18.3 0.2 5.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.4 001280148.1_39725001_3 - 2e-10 40.2 8.2 0.0027 17.8 0.4 8.4 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.4 001280148.1_39725001_3 - 1e-07 32.0 10.6 0.99 10.0 0.4 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.4 001280148.1_39725001_3 - 2.9e-07 29.9 5.9 5.4e-06 25.7 0.6 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.5 001280148.1_39725001_3 - 8.1e-05 22.6 17.9 0.071 13.2 0.8 5.0 3 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.4 001280148.1_39725001_3 - 0.00012 21.5 8.7 5.4 6.7 0.1 5.5 3 1 2 5 5 5 2 TPR repeat TPR_9 PF13371.4 001280148.1_39725001_3 - 0.00015 21.7 2.6 0.087 12.9 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.4 001280148.1_39725001_3 - 0.00051 19.7 9.2 0.08 12.7 0.8 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.12 001280148.1_39725001_3 - 0.0011 18.3 5.8 0.03 13.6 0.3 2.8 1 1 2 3 3 3 2 Coatomer epsilon subunit NARP1 PF12569.6 001280148.1_39725001_3 - 0.023 13.5 4.8 0.94 8.1 0.0 3.1 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 PknG_TPR PF16918.3 001280148.1_39725001_3 - 0.028 13.0 0.2 0.057 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat DUF5112 PF17139.2 001280148.1_39725001_3 - 0.033 13.5 0.3 0.033 13.5 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5112) PPR PF01535.18 001280148.1_39725001_3 - 0.52 10.5 3.1 32 4.9 0.2 4.7 6 0 0 6 6 6 0 PPR repeat TFIIF_alpha PF05793.10 001280450.1_39724001_2 - 2.1e-207 689.8 44.1 2.1e-207 689.8 44.1 1.6 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.10 001280450.1_39724001_2 - 2.6 6.0 46.3 5 5.1 46.3 1.5 1 0 0 1 1 1 0 Nop14-like family CS PF04969.14 001246565.1_39723001_3 - 4.1e-15 56.4 0.0 7.1e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 CS domain Homeobox PF00046.27 001279887.1_39728001_1 - 2.2e-31 107.3 10.9 1.9e-08 33.9 0.1 5.4 5 0 0 5 5 5 5 Homeobox domain Homez PF11569.6 001279887.1_39728001_1 - 3.4e-24 83.9 7.7 1.8e-15 56.0 1.4 4.8 5 0 0 5 5 5 3 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.9 001279887.1_39728001_1 - 8.4e-17 60.7 13.5 0.012 15.3 0.1 5.7 6 0 0 6 6 6 5 Homeobox KN domain zf-Di19 PF05605.10 001279887.1_39728001_1 - 0.016 15.4 3.9 0.044 13.9 3.9 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.4 001279887.1_39728001_1 - 0.029 14.0 6.3 2.4 7.9 2.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.24 001279887.1_39728001_1 - 9.6 6.7 9.2 23 5.6 2.9 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Peptidase_M17 PF00883.19 001246465.1_39724001_1 - 2.4e-125 417.8 0.0 3e-125 417.5 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.15 001246465.1_39724001_1 - 7.3e-22 77.4 0.9 2e-21 76.0 0.1 2.2 3 0 0 3 3 3 1 Cytosol aminopeptidase family, N-terminal domain PAW PF04721.15 001246465.1_39724001_1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Pkinase PF00069.23 001280351.1_39724001_3 - 3e-76 256.1 0.0 3.6e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280351.1_39724001_3 - 1.1e-34 119.8 0.0 1.4e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001280351.1_39724001_3 - 0.013 14.7 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.21 001280351.1_39724001_3 - 0.018 14.9 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.12 001280351.1_39724001_3 - 0.14 11.3 0.0 0.39 9.9 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SnAPC_2_like PF11035.6 001251886.1_39724001_2 - 7.4e-145 483.2 6.0 8.7e-145 483.0 6.0 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Pribosyl_synth PF14572.4 001280188.1_39724001_3 - 8.8e-101 335.4 1.5 1.3e-100 334.9 1.5 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.4 001280188.1_39724001_3 - 1.9e-39 134.1 0.6 4e-39 133.0 0.6 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.25 001280188.1_39724001_3 - 1.3e-08 34.3 0.2 8.6e-07 28.5 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UN_NPL4 PF11543.6 001280188.1_39724001_3 - 0.018 15.4 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RelB PF04221.10 001280188.1_39724001_3 - 0.086 12.7 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 RelB antitoxin WD40 PF00400.30 001246511.1_39725001_2 - 8.3e-32 108.6 32.3 5.4e-05 23.7 0.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.10 001246511.1_39725001_2 - 1e-17 64.3 0.1 2.3e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.6 001246511.1_39725001_2 - 0.083 11.4 8.0 0.12 10.9 0.4 3.0 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Glyco_transf_29 PF00777.16 001193664.1_39723001_1 - 1.7e-67 227.5 0.0 2.1e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Glyco_transf_29 PF00777.16 001193679.1_39722001_1 - 2.5e-32 112.2 1.7 3.8e-32 111.6 1.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) PIF PF05092.10 001193679.1_39722001_1 - 0.013 14.1 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity SPATIAL PF15256.4 001280491.1_39724001_2 - 1.1e-72 244.4 0.1 1.1e-72 244.4 0.1 1.6 2 0 0 2 2 2 1 SPATIAL MGAT2 PF05060.12 001279776.1_39724001_2 - 1.4e-155 517.5 0.8 1.6e-155 517.3 0.8 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) EF-hand_1 PF00036.30 001280236.1_39724001_2 - 2.5e-17 60.9 16.8 0.00011 21.4 0.1 6.0 7 0 0 7 7 7 5 EF hand EF-hand_7 PF13499.4 001280236.1_39724001_2 - 7.8e-16 58.2 17.1 6.5e-07 29.6 0.4 4.2 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001280236.1_39724001_2 - 2.8e-13 48.5 10.3 0.008 15.9 0.1 5.6 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.4 001280236.1_39724001_2 - 5.7e-07 28.6 17.3 0.0045 16.3 0.2 5.4 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.4 001280236.1_39724001_2 - 0.0017 18.0 10.6 0.19 11.4 0.2 4.1 4 2 1 5 5 5 2 EF-hand domain pair Thioredoxin_4 PF13462.4 001280236.1_39724001_2 - 0.11 12.5 0.2 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Thioredoxin Tim44 PF04280.13 001280516.1_39724001_3 - 1.3e-42 145.2 0.0 4.3e-42 143.6 0.0 1.8 2 0 0 2 2 2 1 Tim44-like domain SCIFF PF13165.4 001280516.1_39724001_3 - 0.015 15.1 0.3 0.042 13.7 0.3 1.7 1 0 0 1 1 1 0 Six-cysteine peptide SCIFF RecG_N PF17190.2 001280516.1_39724001_3 - 0.18 12.4 3.8 0.25 12.0 0.9 2.7 2 1 1 3 3 3 0 RecG N-terminal helical domain FmrO PF07091.9 001280516.1_39724001_3 - 0.21 11.0 0.5 0.34 10.3 0.5 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF3347 PF11827.6 001280516.1_39724001_3 - 4.1 7.4 9.5 36 4.3 7.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) DUF3504 PF12012.6 001280146.1_39727001_3 - 1.5e-61 206.9 0.7 1.5e-61 206.9 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) CARD PF00619.19 001280146.1_39727001_3 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain PX PF00787.22 001246380.1_39725001_2 - 8.9e-26 90.0 0.5 1.4e-25 89.4 0.5 1.3 1 0 0 1 1 1 1 PX domain Sushi PF00084.18 001193675.1_39729001_1 - 5.4e-270 872.2 174.6 7.4e-13 48.8 1.4 30.5 30 0 0 30 30 30 30 Sushi repeat (SCR repeat) Invas_SpaK PF03519.12 001193675.1_39729001_1 - 1.3e-06 28.3 0.0 8 6.5 0.0 4.4 4 0 0 4 4 4 3 Invasion protein B family DUF1737 PF08410.8 001193675.1_39729001_1 - 0.0031 17.2 0.0 7.3 6.4 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF1737) DUF3857 PF12969.5 001193675.1_39729001_1 - 0.066 13.2 0.0 60 3.5 0.0 3.4 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3857) DUF2441 PF10386.7 001193675.1_39729001_2 - 0.029 14.2 3.0 32 4.4 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2441) EF-hand_7 PF13499.4 001246654.1_39724001_3 - 7e-09 35.9 4.8 2.5e-06 27.7 0.0 4.3 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.4 001246654.1_39724001_3 - 1.6e-05 24.3 4.1 0.73 9.8 0.1 5.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.30 001246654.1_39724001_3 - 7.7e-05 21.8 0.1 0.32 10.5 0.0 3.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.4 001246654.1_39724001_3 - 0.026 14.2 0.0 3.1 7.5 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.4 001246654.1_39724001_3 - 0.04 13.3 0.2 0.23 10.9 0.0 2.4 2 0 0 2 2 2 0 EF hand RWD PF05773.20 001280165.1_39724001_1 - 6.6e-17 61.7 0.0 1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.10 001280165.1_39724001_1 - 1.9e-14 53.8 0.0 3.5e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PRP21_like_P PF12230.6 001280536.1_39726001_3 - 6.6e-52 176.4 9.4 6.6e-52 176.4 9.4 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.18 001280536.1_39726001_3 - 6e-46 154.1 7.1 3.4e-24 84.4 0.4 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.21 001280536.1_39726001_3 - 8.8e-18 63.7 0.0 1.9e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.4 001280536.1_39726001_3 - 0.0019 18.5 0.0 0.0054 17.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.6 001280536.1_39726001_3 - 0.12 12.1 0.8 0.39 10.5 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Toprim_Crpt PF13342.4 001280536.1_39726001_3 - 0.35 10.8 2.4 16 5.4 0.1 2.9 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase Ribosomal_S7e PF01251.16 001252001.1_39722001_3 - 1e-93 312.1 3.8 1.2e-93 311.9 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e NUDIX PF00293.26 001280433.1_39724001_2 - 2.1e-08 34.1 0.3 5.3e-08 32.8 0.3 1.6 1 1 0 1 1 1 1 NUDIX domain DEAD PF00270.27 001280138.1_39724001_2 - 3.8e-29 101.6 0.0 6.3e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001280138.1_39724001_2 - 1.2e-26 93.1 0.0 3.1e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.23 001280337.1_39725001_2 - 2.4e-44 151.5 0.0 3e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280337.1_39725001_2 - 8.6e-19 67.7 0.0 1.1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001280337.1_39725001_2 - 2.2e-09 36.9 0.0 6e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like HMG_box PF00505.17 001194942.1_39722001_1 - 1.7e-31 108.3 19.2 5.1e-21 74.7 5.5 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.8 001194942.1_39722001_1 - 1.1e-21 77.1 15.9 1.2e-13 51.3 4.6 2.4 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.11 001194942.1_39722001_1 - 0.00066 20.1 9.3 0.019 15.4 0.1 2.7 1 1 2 3 3 3 2 YABBY protein HMG_box_5 PF14887.4 001194942.1_39722001_1 - 0.0014 18.4 2.2 0.0014 18.4 2.2 2.2 1 1 1 2 2 2 1 HMG (high mobility group) box 5 NAD_binding_9 PF13454.4 001194942.1_39722001_1 - 0.025 14.4 0.2 0.055 13.4 0.1 1.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding DUF1014 PF06244.10 001194942.1_39722001_1 - 0.074 13.5 0.3 0.074 13.5 0.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DUF1074 PF06382.9 001194942.1_39722001_1 - 0.093 12.8 8.2 2 8.4 0.7 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1074) Complex1_LYR_2 PF13233.4 001194942.1_39722001_1 - 3.4 8.3 11.0 7.6 7.2 3.7 2.7 1 1 1 2 2 2 0 Complex1_LYR-like DUF2207 PF09972.7 001194942.1_39722001_1 - 4.5 5.8 7.4 3.3 6.2 6.3 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) 7tm_1 PF00001.19 001279878.1_39724001_3 - 1.6e-45 155.3 11.7 1.6e-45 155.3 11.7 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001279878.1_39724001_3 - 2.6e-08 33.4 28.3 6.1e-08 32.2 13.2 2.9 3 1 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1777 PF08648.10 001280385.1_39724001_1 - 1.7 8.7 25.5 2.4 8.2 25.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Hexapep PF00132.22 001280385.1_39724001_2 - 0.00027 20.4 1.8 0.0012 18.4 1.1 1.7 1 1 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) DEAD PF00270.27 001280385.1_39724001_3 - 4.9e-41 140.3 0.2 7.9e-41 139.6 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001280385.1_39724001_3 - 8.3e-31 106.5 0.0 4.3e-30 104.2 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.13 001280385.1_39724001_3 - 0.0002 21.3 0.0 0.0004 20.3 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.4 001280385.1_39724001_3 - 0.0035 17.5 3.4 0.0039 17.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain DUF1477 PF07346.9 001280477.1_39725001_1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) RINGv PF12906.5 001280477.1_39725001_2 - 7.6e-15 54.6 9.8 1.8e-14 53.4 9.8 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.4 001280477.1_39725001_2 - 0.015 15.4 9.9 0.015 15.4 9.9 2.6 3 0 0 3 3 3 0 Ring finger domain Baculo_IE-1 PF05290.9 001280477.1_39725001_2 - 0.034 14.0 0.7 0.077 12.8 0.7 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) LRR_8 PF13855.4 001144863.1_39726001_1 - 1.2e-49 165.7 98.6 2.7e-11 42.9 0.3 10.7 4 2 11 15 15 14 13 Leucine rich repeat TIR PF01582.18 001144863.1_39726001_1 - 2.7e-35 121.6 0.1 4.6e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.5 001144863.1_39726001_1 - 1.2e-28 98.4 55.7 1.9e-06 27.9 1.5 11.7 7 2 5 13 13 13 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001144863.1_39726001_1 - 4.3e-11 42.5 14.4 9.5e-05 21.8 0.0 4.6 3 2 2 5 5 5 4 Leucine-rich repeat TIR_2 PF13676.4 001144863.1_39726001_1 - 2.5e-09 37.2 0.1 4.7e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.31 001144863.1_39726001_1 - 2.6e-08 33.0 52.4 0.16 12.4 0.4 15.2 13 4 0 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.4 001144863.1_39726001_1 - 1.8e-05 24.3 52.2 0.39 10.8 1.1 13.2 16 0 0 16 16 16 4 Leucine Rich repeat DUF1863 PF08937.9 001144863.1_39726001_1 - 9.4e-05 22.6 0.5 0.00042 20.5 0.5 2.0 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) Curto_V2 PF07325.9 001144863.1_39726001_1 - 0.086 12.6 0.3 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 Curtovirus V2 protein EamA PF00892.18 001328316.1_39725001_3 - 5.8e-18 65.2 31.3 2e-09 37.6 7.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family DP PF08781.8 001251920.1_39725001_1 - 1.8e-64 215.7 1.0 3.1e-64 214.9 1.0 1.4 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.18 001251920.1_39725001_1 - 1.1e-26 92.5 0.1 2e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain PC_rep PF01851.20 001246549.1_39727001_1 - 3e-42 140.9 20.4 6.9e-09 35.6 0.0 7.8 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.4 001246549.1_39727001_1 - 6.6e-21 74.4 0.8 1.4e-14 54.1 0.0 5.5 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.20 001246549.1_39727001_1 - 1.9e-05 24.3 0.7 1.4 9.2 0.1 5.0 4 0 0 4 4 4 1 HEAT repeat HEAT_PBS PF03130.14 001246549.1_39727001_1 - 0.0013 19.1 0.6 7 7.5 0.0 4.5 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.4 001246549.1_39727001_1 - 0.0019 18.5 0.9 1.9 8.9 0.1 4.9 4 1 2 6 6 6 2 HEAT-like repeat Cnd1 PF12717.5 001246549.1_39727001_1 - 0.056 13.3 1.3 1.1 9.1 0.0 3.5 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 PA26 PF04636.11 001246549.1_39727001_1 - 0.07 11.9 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Tim54 PF11711.6 001246549.1_39727001_1 - 0.28 9.8 7.1 0.43 9.2 7.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.6 001246549.1_39727001_1 - 1.2 7.7 13.0 2.7 6.6 13.0 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_Ag35 PF03286.12 001246549.1_39727001_1 - 3.7 7.2 13.2 7.3 6.2 13.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4775 PF16001.3 001246549.1_39727001_1 - 7.3 5.7 19.8 15 4.7 19.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Colipase PF01114.16 001246549.1_39727001_2 - 0.22 11.1 3.4 0.57 9.8 3.4 1.6 1 0 0 1 1 1 0 Colipase, N-terminal domain ig PF00047.23 001105153.1_39723001_1 - 8.4e-34 115.5 0.0 8.6e-12 44.9 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001105153.1_39723001_1 - 1.2e-16 60.6 0.0 1.9e-06 28.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001105153.1_39723001_1 - 1.4e-15 57.6 0.0 3.6e-05 24.2 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001105153.1_39723001_1 - 0.00013 21.9 0.4 0.56 10.3 0.0 4.7 4 2 1 5 5 5 1 Immunoglobulin V-set domain SIT PF15330.4 001105153.1_39723001_1 - 0.00063 20.0 0.1 0.0019 18.5 0.0 1.8 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT Ig_4 PF16680.3 001105153.1_39723001_1 - 0.084 13.1 0.4 5.9 7.2 0.0 3.7 4 2 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain ig PF00047.23 001048050.2_39723001_2 - 5.6e-19 68.0 0.0 7.3e-06 25.9 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001048050.2_39723001_2 - 1.7e-16 60.5 0.0 2.8e-05 24.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001048050.2_39723001_2 - 7.2e-15 55.0 0.1 3.2e-05 24.0 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001048050.2_39723001_2 - 0.00057 19.9 3.2 3.6 7.7 0.0 4.9 4 2 1 5 5 5 1 Immunoglobulin V-set domain APOBEC_N PF08210.9 001289639.1_39723001_1 - 4.8e-99 329.4 5.5 1.4e-50 171.6 2.5 2.0 2 0 0 2 2 2 2 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001289639.1_39723001_1 - 2.5e-63 209.8 0.3 3.8e-31 106.7 0.2 2.4 2 0 0 2 2 2 2 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001289639.1_39723001_1 - 0.0037 17.0 0.1 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Viral_Rep PF02407.14 001289639.1_39723001_1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative viral replication protein Toxin-deaminase PF14424.4 001289639.1_39723001_1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Ig_2 PF13895.4 001009026.1_39724001_2 - 1.6e-34 117.9 0.3 2.7e-11 43.5 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.23 001009026.1_39724001_2 - 3.8e-21 74.9 0.1 3e-06 27.2 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.4 001009026.1_39724001_2 - 4.3e-21 75.2 0.2 4.4e-06 27.1 0.0 4.7 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.15 001009026.1_39724001_2 - 5.8e-05 23.1 2.3 3.4 7.8 0.2 5.5 4 3 0 5 5 5 2 Immunoglobulin V-set domain I-set PF07679.14 001009026.1_39724001_2 - 0.0018 18.2 0.0 10 6.2 0.0 3.9 3 2 0 3 3 3 2 Immunoglobulin I-set domain Adeno_E3_CR1 PF02440.13 001009026.1_39724001_2 - 0.053 13.2 0.0 2.1 8.1 0.0 2.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 UPF0688 PF15772.3 001251898.2_39724001_3 - 7.5e-115 383.0 11.7 9.6e-115 382.6 11.7 1.1 1 0 0 1 1 1 1 UPF0688 family ART PF01129.16 001280372.1_39724001_1 - 9e-83 276.8 0.3 1.2e-82 276.4 0.3 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase DUF1652 PF07865.9 001280355.1_39724001_1 - 0.14 11.9 1.3 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) DoxX_2 PF13564.4 001280355.1_39724001_2 - 2.1e-05 24.4 1.7 3.6e-05 23.7 1.7 1.3 1 0 0 1 1 1 1 DoxX-like family P21-Arc PF04062.12 001251913.1_39722001_1 - 9.2e-82 273.1 0.1 1e-81 272.9 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit IFT46_B_C PF12317.6 001279807.1_39724001_2 - 9.2e-104 345.7 1.1 1.2e-103 345.3 1.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal CNDH2_C PF16858.3 001279807.1_39724001_2 - 1.2 8.9 8.2 2.1 8.1 8.2 1.5 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAM176 PF14851.4 001279807.1_39724001_2 - 1.6 8.2 4.8 3 7.4 3.7 2.0 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.10 001279807.1_39724001_2 - 4.1 6.6 8.4 7.9 5.6 8.4 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.9 001279807.1_39724001_2 - 5.6 6.9 8.3 0.48 10.3 2.5 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.4 001279807.1_39724001_2 - 9.5 6.6 14.4 8 6.8 10.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_1 PF00561.18 001246637.1_39725001_1 - 1.7e-23 83.5 0.1 9.8e-18 64.6 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001246637.1_39725001_1 - 4.5e-16 58.7 1.4 8.4e-15 54.5 1.4 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.5 001246637.1_39725001_1 - 1.7e-14 54.8 0.1 1.7e-14 54.8 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.14 001246637.1_39725001_1 - 0.0028 17.3 0.1 1.7 8.3 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF2920 PF11144.6 001246637.1_39725001_1 - 0.006 15.7 0.0 1.5 7.8 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2920) DUF4604 PF15377.4 001246637.1_39725001_1 - 0.028 14.7 13.5 0.046 14.0 13.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) FSH1 PF03959.11 001246637.1_39725001_1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.19 001246637.1_39725001_1 - 0.037 13.4 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.8 001246637.1_39725001_1 - 0.039 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 TAP-like protein Peptidase_S15 PF02129.16 001246637.1_39725001_1 - 0.049 13.1 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_8 PF06259.10 001246637.1_39725001_1 - 0.11 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase SR-25 PF10500.7 001246637.1_39725001_3 - 8.9 5.7 35.4 13 5.2 35.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_L37e PF01907.17 001246471.1_39721001_1 - 7.8e-27 93.1 15.1 1.5e-26 92.2 15.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.5 001246471.1_39721001_1 - 0.0087 15.9 1.6 0.015 15.2 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon FeS PF04060.11 001246471.1_39721001_1 - 0.97 9.0 4.0 0.79 9.3 0.7 2.1 2 0 0 2 2 2 0 Putative Fe-S cluster Actin PF00022.17 001271671.1_39725001_2 - 6.2e-148 492.6 0.0 7.4e-148 492.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.11 001271671.1_39725001_2 - 0.012 14.3 0.0 0.038 12.7 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein SPRY PF00622.26 001280479.1_39724001_1 - 1.7e-18 66.8 0.5 2.6e-18 66.1 0.5 1.3 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.4 001280479.1_39724001_1 - 3.4e-08 33.1 14.0 9.1e-08 31.7 14.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001280479.1_39724001_1 - 3.4e-05 23.5 11.0 0.0001 22.0 11.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 CAF1 PF04857.18 001246536.1_39724001_3 - 2.3e-22 79.5 5.1 3.7e-11 42.6 0.1 3.3 2 1 0 3 3 3 3 CAF1 family ribonuclease SR-25 PF10500.7 001246536.1_39724001_3 - 0.054 13.0 18.5 0.085 12.3 18.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bax1-I PF01027.18 001246410.1_39726001_1 - 1.9e-41 142.1 20.5 3.4e-41 141.2 20.5 1.4 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.9 001246410.1_39726001_1 - 0.7 9.6 21.6 2.1 8.1 6.9 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling RRM_1 PF00076.20 001251846.1_39729001_1 - 4.8e-30 103.1 1.0 1.7e-07 30.8 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGM_PMM_I PF02878.14 001279797.1_39725001_2 - 2.7e-18 65.9 0.0 8.3e-08 31.9 0.0 2.7 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.18 001279797.1_39725001_2 - 2.9e-11 43.3 0.1 8.3e-11 41.8 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.14 001279797.1_39725001_2 - 0.00039 20.5 0.2 0.00098 19.2 0.2 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Ribosomal_L22 PF00237.17 001279797.1_39725001_2 - 0.044 14.1 0.5 0.097 13.0 0.5 1.5 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e WAP PF00095.19 001135852.1_39722001_2 - 9.1e-17 61.1 41.2 1.9e-08 34.4 18.9 2.2 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pkinase PF00069.23 001280020.1_39724001_3 - 1.1e-72 244.5 0.0 1.8e-72 243.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280020.1_39724001_3 - 1.1e-53 182.0 0.0 1.6e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.6 001280020.1_39724001_3 - 7.2e-25 86.7 3.4 1.5e-24 85.6 3.4 1.6 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Abi_2 PF07751.9 001280020.1_39724001_3 - 0.02 15.1 0.6 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Abi-like protein DUF4611 PF15387.4 001280020.1_39724001_3 - 0.3 11.2 5.4 0.18 11.9 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) tRNA-synt_2d PF01409.18 001246464.1_39724001_1 - 1.5e-90 302.9 0.0 2e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) MarR_2 PF12802.5 001246464.1_39724001_1 - 6.3e-05 22.7 0.5 0.00024 20.8 0.5 2.0 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.10 001246464.1_39724001_1 - 0.00023 20.9 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 HTH domain tRNA-synt_2 PF00152.18 001246464.1_39724001_1 - 0.0012 17.8 0.3 0.0041 16.1 0.0 1.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF4196 PF13846.4 001280316.1_39724001_3 - 2.7e-52 175.7 26.9 3.7e-41 139.9 12.1 5.4 4 2 2 6 6 6 2 Domain of unknown function (DUF4196) DUF4211 PF13926.4 001280316.1_39724001_3 - 7.3e-34 116.8 1.2 2.2e-33 115.2 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) F-box-like PF12937.5 001280121.1_39725001_2 - 3.8e-05 23.4 0.1 8.6e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001280121.1_39725001_2 - 0.0021 17.7 1.2 0.0043 16.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain BTK PF00779.17 001280121.1_39725001_2 - 0.0047 16.6 1.3 0.013 15.1 1.3 1.8 1 0 0 1 1 1 1 BTK motif Glyco_transf_29 PF00777.16 001037308.1_39723001_1 - 1.1e-36 126.5 0.1 1.5e-36 126.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF2611 PF11022.6 001037308.1_39723001_1 - 0.035 14.4 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Spt20 PF12090.6 001037308.1_39723001_1 - 3.6 7.0 8.2 5.5 6.4 8.2 1.2 1 0 0 1 1 1 0 Spt20 family AMP-binding PF00501.26 001280439.1_39725001_2 - 5.6e-96 321.6 0.0 6.7e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.4 001280439.1_39725001_2 - 1.3e-17 64.4 0.6 2.7e-17 63.4 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Peptidase_C2 PF00648.19 001280269.1_39726001_2 - 5.4e-125 416.2 0.0 7.5e-125 415.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.20 001280269.1_39726001_2 - 5.2e-51 172.5 0.0 9.6e-51 171.7 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.30 001280269.1_39726001_2 - 1.3e-10 39.9 1.3 0.00041 19.6 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.4 001280269.1_39726001_2 - 5.2e-09 35.6 2.8 2.3e-06 27.1 0.1 3.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.4 001280269.1_39726001_2 - 5.9e-07 28.8 1.4 0.022 14.6 0.0 3.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.4 001280269.1_39726001_2 - 0.00047 20.4 4.1 0.26 11.7 0.2 3.5 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.4 001280269.1_39726001_2 - 0.061 12.7 1.0 1.3 8.5 0.1 2.9 3 0 0 3 3 3 0 EF hand EF-hand_10 PF14788.4 001280269.1_39726001_2 - 0.096 12.4 0.1 0.57 10.0 0.0 2.3 2 0 0 2 2 2 0 EF hand Proteasome PF00227.24 001246657.1_39722001_3 - 4.5e-54 182.7 0.2 5.7e-54 182.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.7 001246657.1_39722001_3 - 5.5e-15 54.6 0.1 9.7e-15 53.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Transglut_N PF00868.18 001130909.1_39725001_1 - 1.8e-32 112.0 0.3 3.8e-32 111.0 0.3 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.20 001130909.1_39725001_1 - 7.4e-21 74.1 2.9 7.5e-20 70.9 0.1 2.8 3 0 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.17 001130909.1_39725001_1 - 3.3e-17 62.8 0.4 6.1e-17 62.0 0.4 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily A2M_N PF01835.17 001130909.1_39725001_1 - 0.021 15.1 0.1 0.096 13.0 0.0 2.1 2 0 0 2 2 2 0 MG2 domain ASH PF15780.3 001130909.1_39725001_1 - 0.051 13.7 0.2 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin NPCBM_assoc PF10633.7 001130909.1_39725001_1 - 0.085 13.0 1.0 2.8 8.1 0.0 3.1 3 1 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Myb_DNA-bind_2 PF08914.9 001280213.1_39725001_3 - 2.5e-31 107.5 0.2 4.4e-31 106.7 0.2 1.4 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.3 001280213.1_39725001_3 - 1.2e-15 57.5 0.0 2.9e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1_C PF11626.6 001280213.1_39725001_3 - 9.1e-12 44.8 0.2 5.1e-11 42.4 0.1 2.2 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_6 PF13921.4 001280213.1_39725001_3 - 0.076 13.1 0.1 0.7 10.1 0.1 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain BAG PF02179.14 001246454.1_39725001_1 - 1.5e-47 159.7 23.1 1.4e-15 57.3 0.2 5.1 5 0 0 5 5 5 4 BAG domain DUF2682 PF10909.6 001246454.1_39725001_1 - 0.59 10.5 4.2 8.7 6.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2682) FimP PF09766.7 001280523.1_39726001_1 - 2.2e-130 435.0 6.1 3.6e-130 434.3 6.1 1.3 1 0 0 1 1 1 1 Fms-interacting protein Enolase_C PF00113.20 001220779.1_39724001_1 - 1.8e-156 519.8 0.0 2.4e-156 519.3 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.14 001220779.1_39724001_1 - 3.8e-61 204.9 0.1 6e-61 204.2 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.4 001220779.1_39724001_1 - 5.7e-08 32.6 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.9 001220779.1_39724001_1 - 0.0026 16.8 0.4 0.0055 15.8 0.4 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DnaJ PF00226.29 001246535.1_39723001_3 - 3.5e-27 94.2 1.0 6.2e-27 93.4 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain EMP70 PF02990.14 001246535.1_39723001_3 - 0.02 13.4 0.1 0.027 13.0 0.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 TMEM52 PF14979.4 001246535.1_39723001_3 - 1.4 8.7 10.5 51 3.6 0.0 2.2 2 0 0 2 2 2 0 Transmembrane 52 Peptidase_M14 PF00246.22 001280475.1_39724001_3 - 1.7e-79 267.6 0.0 2.1e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.14 001280475.1_39724001_3 - 4.3e-18 65.3 0.0 8.5e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide SSTK-IP PF15836.3 001251957.1_39721001_1 - 2.2e-68 228.0 5.8 2.4e-68 227.9 5.8 1.0 1 0 0 1 1 1 1 SSTK-interacting protein, TSSK6-activating co-chaperone protein eIF_4EBP PF05456.9 001204162.1_39722001_1 - 1.7e-37 127.7 0.9 2.6e-37 127.1 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Vma12 PF11712.6 001242622.1_39723001_2 - 3.9e-26 91.6 0.2 5.7e-26 91.1 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.23 001280296.1_39725001_3 - 4.6e-59 199.8 0.0 6.5e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280296.1_39725001_3 - 1.8e-23 83.0 0.0 3.5e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001280296.1_39725001_3 - 1.1e-05 25.3 0.1 0.0037 17.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.12 001280296.1_39725001_3 - 0.0031 16.7 0.4 0.0052 16.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.18 001280296.1_39725001_3 - 0.015 14.7 1.2 0.027 13.9 1.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.20 001280296.1_39725001_3 - 0.021 14.3 0.4 0.047 13.2 0.4 1.5 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.4 001280296.1_39725001_3 - 0.12 11.8 0.9 0.72 9.3 0.3 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.7 001280296.1_39725001_3 - 0.13 11.6 1.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Orn_Arg_deC_N PF02784.14 001279911.1_39725001_2 - 1.4e-88 296.4 0.0 1.7e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001279911.1_39725001_2 - 2e-34 117.9 0.0 5.5e-34 116.4 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Granin PF01271.15 001279910.1_39726001_1 - 2e-253 842.5 90.0 2.3e-253 842.3 90.0 1.0 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) ubiquitin PF00240.21 001328325.1_39725001_1 - 3.6e-18 64.9 0.3 6.3e-18 64.1 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.29 001328325.1_39725001_1 - 3.4e-07 29.9 0.2 9.7e-07 28.4 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.6 001328325.1_39725001_1 - 1.9e-05 24.2 0.2 3e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.4 001328325.1_39725001_1 - 0.0057 16.6 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001328325.1_39725001_1 - 0.0074 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain YukD PF08817.8 001328325.1_39725001_1 - 0.012 16.2 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD HOIP-UBA PF16678.3 001328325.1_39725001_1 - 0.019 14.8 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase ExbD PF02472.14 001328325.1_39725001_1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DSPc PF00782.18 001302401.1_39723001_1 - 8.2e-28 96.7 0.0 1.2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.4 001302401.1_39723001_1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.25 001302401.1_39723001_1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase REV PF00424.16 001302401.1_39723001_2 - 2.1 8.3 6.3 7.4 6.5 6.3 1.9 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Mito_carr PF00153.25 001246423.1_39724001_3 - 1.8e-48 162.3 7.5 7.4e-19 67.3 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein HEAT PF02985.20 001280173.1_39725001_3 - 2.7e-49 160.7 26.7 0.00024 20.9 0.0 13.7 15 0 0 15 15 15 12 HEAT repeat HEAT_2 PF13646.4 001280173.1_39725001_3 - 7.6e-45 151.1 7.9 4.7e-14 52.4 0.0 7.3 2 1 6 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.5 001280173.1_39725001_3 - 1.1e-15 57.8 1.4 0.014 15.8 0.0 8.3 5 3 5 10 10 10 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.5 001280173.1_39725001_3 - 1.4e-12 47.8 6.7 0.00011 22.1 0.9 4.9 2 1 3 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.4 001280173.1_39725001_3 - 2e-11 43.9 15.3 0.0053 17.1 0.0 9.1 8 2 3 11 11 11 4 HEAT-like repeat Adaptin_N PF01602.18 001280173.1_39725001_3 - 1.3e-09 37.1 5.2 0.0038 15.7 2.6 3.6 1 1 3 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.6 001280173.1_39725001_3 - 1.9e-05 24.2 3.1 0.047 13.1 0.0 5.0 1 1 3 5 5 5 1 CLASP N terminal M11L PF11099.6 001280173.1_39725001_3 - 2e-05 24.8 0.7 0.0012 19.0 0.0 3.4 2 2 2 4 4 4 1 Apoptosis regulator M11L like TAF6_C PF07571.11 001280173.1_39725001_3 - 0.0018 18.4 0.6 1.6 9.0 0.0 4.5 3 3 1 4 4 4 1 TAF6 C-terminal HEAT repeat domain Cas_Csm6 PF09659.8 001280173.1_39725001_3 - 0.04 12.6 0.1 0.064 11.9 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) HEAT_PBS PF03130.14 001280173.1_39725001_3 - 0.078 13.6 0.1 66 4.5 0.0 5.0 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Semenogelin PF05474.9 001110538.1_39725001_1 - 0 1382.7 173.5 2.5e-262 871.5 85.2 2.2 1 1 2 3 3 3 3 Semenogelin Kelch_6 PF13964.4 001246514.1_39724001_2 - 6.1e-43 143.6 8.7 7.7e-08 32.2 0.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.13 001246514.1_39724001_2 - 2.8e-40 134.7 11.4 9.6e-10 37.9 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.23 001246514.1_39724001_2 - 2.8e-38 129.1 6.7 4.7e-07 29.2 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.4 001246514.1_39724001_2 - 1.9e-31 107.6 10.4 1.6e-06 28.1 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.4 001246514.1_39724001_2 - 5.4e-31 105.9 12.8 3.5e-06 26.7 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.4 001246514.1_39724001_2 - 1.8e-30 104.5 12.0 3.5e-07 30.0 0.3 6.9 5 1 1 6 6 6 5 Galactose oxidase, central domain Glyco_transf_10 PF00852.17 001009088.1_39723001_1 - 2.4e-68 229.2 0.3 3e-68 228.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.3 001009088.1_39723001_1 - 1.1e-35 122.3 0.0 2e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DUF2076 PF09849.7 001009088.1_39723001_3 - 1.6 8.6 9.0 0.043 13.7 2.5 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Borealin PF10512.7 001246430.1_39725001_3 - 1.9e-30 105.1 0.0 4.8e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Nbl1_Borealin_N PF10444.7 001246430.1_39725001_3 - 5.5e-21 73.8 1.5 1.8e-19 69.0 1.2 2.2 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal PET PF06297.12 001280535.1_39726001_2 - 4e-38 129.5 0.7 9.1e-38 128.3 0.7 1.7 1 0 0 1 1 1 1 PET Domain LIM PF00412.20 001280535.1_39726001_2 - 8.5e-25 86.6 38.9 2.4e-09 37.1 3.0 3.6 3 0 0 3 3 3 3 LIM domain Vasculin PF15337.4 001280535.1_39726001_2 - 0.0096 16.6 2.7 0.028 15.1 0.0 2.9 3 0 0 3 3 3 1 Vascular protein family Vasculin-like 1 Atx10homo_assoc PF09759.7 001280473.1_39724001_2 - 8.8e-39 131.4 3.7 5e-35 119.4 0.4 3.5 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain RIH_assoc PF08454.9 001280473.1_39724001_2 - 0.0065 16.2 0.5 0.0065 16.2 0.5 2.5 3 1 0 3 3 3 1 RyR and IP3R Homology associated RRM_5 PF13893.4 001280380.1_39724001_1 - 1.1e-59 199.4 0.1 1.1e-44 150.9 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 001280380.1_39724001_1 - 1.5e-30 104.6 0.2 6.7e-10 38.5 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001280380.1_39724001_1 - 1.1e-07 31.5 0.5 0.53 10.0 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif Ribosomal_S26e PF01283.17 001252589.1_39722001_2 - 4.2e-54 181.4 7.3 5.3e-54 181.1 7.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.5 001252589.1_39722001_2 - 0.0046 17.4 0.4 0.038 14.5 0.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Peptidase_M24 PF00557.22 001280330.1_39725001_3 - 1.1e-49 168.8 0.0 1.5e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.3 001280330.1_39725001_3 - 1.7e-46 158.1 0.0 2.5e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.3 001280330.1_39725001_3 - 2.4e-23 81.8 0.1 6.7e-23 80.4 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.16 001280330.1_39725001_3 - 1.1e-12 48.6 0.0 1.1e-10 42.1 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain UCH PF00443.27 001009110.1_39729001_1 - 1.3e-08 34.5 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.4 001009110.1_39729001_1 - 0.00032 20.3 0.1 0.00074 19.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RasGEF_N PF00618.18 001009110.1_39729001_2 - 0.1 12.7 0.3 0.57 10.3 0.0 2.5 2 0 0 2 2 2 0 RasGEF N-terminal motif Vps23_core PF09454.8 001009110.1_39729001_2 - 0.74 9.7 2.8 1.1 9.1 0.0 2.8 4 0 0 4 4 4 0 Vps23 core domain UCH PF00443.27 001009110.1_39729001_3 - 5.5e-13 48.9 0.3 8.9e-13 48.2 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Diphthami_syn_2 PF01902.15 001280404.1_39725001_1 - 2.8e-44 151.1 0.2 5.5e-44 150.1 0.2 1.4 1 1 0 1 1 1 1 Diphthamide synthase Glyco_transf_10 PF00852.17 001009150.1_39723001_1 - 2.6e-66 222.6 0.3 3.3e-66 222.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.3 001009150.1_39723001_1 - 2.9e-37 127.4 0.0 4.9e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DUF2076 PF09849.7 001009150.1_39723001_3 - 0.35 10.7 2.4 0.68 9.8 2.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) tRNA-synt_His PF13393.4 001246379.1_39725001_2 - 1.3e-40 139.5 0.0 2.5e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.18 001246379.1_39725001_2 - 2.5e-17 62.7 0.9 5.2e-17 61.7 0.9 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.5 001246379.1_39725001_2 - 2e-11 43.7 0.3 3.4e-11 43.0 0.3 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs WHEP-TRS PF00458.18 001246379.1_39725001_2 - 3.4e-10 39.8 5.2 1e-09 38.3 5.2 1.8 1 0 0 1 1 1 1 WHEP-TRS domain HHH_3 PF12836.5 001246379.1_39725001_2 - 0.02 15.0 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Virul_Fac PF10139.7 001246379.1_39725001_2 - 0.11 10.6 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor PIP5K PF01504.16 001137558.2_39728001_2 - 7.3e-92 307.3 0.0 9.6e-92 307.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ig_2 PF13895.4 001008981.1_39724001_3 - 9e-32 109.1 2.8 4.8e-15 55.5 0.1 4.3 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.4 001008981.1_39724001_3 - 1.3e-25 89.6 4.9 2.2e-06 28.0 0.3 4.5 4 1 0 4 4 4 4 Immunoglobulin domain ig PF00047.23 001008981.1_39724001_3 - 2e-12 47.0 2.9 0.059 13.4 0.3 5.1 4 1 0 4 4 4 4 Immunoglobulin domain YusW PF14039.4 001279781.1_39725001_1 - 2 8.9 9.1 0.13 12.6 1.6 2.9 2 1 2 4 4 4 0 YusW-like protein Prenyltrans PF00432.19 001302412.1_39724001_1 - 1.5e-55 184.5 16.9 6.5e-12 44.8 0.2 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.4 001302412.1_39724001_1 - 0.0057 15.7 0.0 4 6.3 0.0 3.0 1 1 2 3 3 3 3 Squalene-hopene cyclase C-terminal domain DUF4604 PF15377.4 001302412.1_39724001_1 - 0.013 15.8 11.3 0.019 15.3 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SR-25 PF10500.7 001302412.1_39724001_1 - 7.7 5.9 27.7 11 5.4 27.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.7 001302412.1_39724001_2 - 0.037 13.5 21.4 0.069 12.6 21.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med19 PF10278.7 001302412.1_39724001_2 - 0.67 9.7 20.2 0.9 9.3 20.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_polI_A34 PF08208.9 001302412.1_39724001_2 - 7.1 6.6 23.3 10 6.0 23.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4604 PF15377.4 001302412.1_39724001_3 - 0.11 12.8 13.2 0.16 12.3 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) 7TM_GPCR_Srv PF10323.7 001302412.1_39724001_3 - 1.3 8.1 3.8 1.9 7.6 3.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv SPATA6 PF14909.4 001280538.1_39724001_2 - 6.3e-52 175.3 0.0 9.2e-52 174.8 0.0 1.2 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 SKIP_SNW PF02731.13 001280438.1_39725001_3 - 1.7e-75 252.0 7.6 6.2e-75 250.1 7.6 2.0 1 0 0 1 1 1 1 SKIP/SNW domain HLH PF00010.24 001243846.1_39722001_1 - 1.1e-10 41.1 3.2 1.7e-10 40.5 3.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sel1 PF08238.10 001280149.1_39724001_3 - 1.2e-24 86.0 20.0 3.3e-06 27.4 1.4 6.0 6 0 0 6 6 6 5 Sel1 repeat TPR_2 PF07719.15 001280149.1_39724001_3 - 1.8e-05 24.3 14.7 0.00027 20.7 1.2 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.4 001280149.1_39724001_3 - 0.00047 20.0 11.6 0.0062 16.5 0.5 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.4 001280149.1_39724001_3 - 0.004 17.5 3.9 0.2 12.0 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.18 001280149.1_39724001_3 - 0.005 16.9 0.2 0.63 10.3 0.1 3.2 2 0 0 2 2 2 1 PPR repeat TPR_6 PF13174.4 001280149.1_39724001_3 - 0.0079 16.6 12.9 3.1 8.5 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.26 001280149.1_39724001_3 - 0.019 14.7 15.0 0.05 13.3 0.7 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001280149.1_39724001_3 - 0.037 14.1 1.7 0.15 12.1 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.4 001280149.1_39724001_3 - 0.12 13.0 0.1 0.12 13.0 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.4 001280149.1_39724001_3 - 0.16 11.6 15.4 0.2 11.2 1.0 4.7 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.4 001280149.1_39724001_3 - 0.19 12.5 3.7 7 7.6 0.1 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.4 001280149.1_39724001_3 - 4.1 7.6 10.2 0.82 9.9 0.3 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Pou PF00157.15 001302427.1_39723001_1 - 2.4e-38 129.9 0.2 4e-38 129.2 0.2 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.27 001302427.1_39723001_1 - 1.1e-18 66.7 1.4 2e-18 65.8 0.3 2.0 2 0 0 2 2 2 1 Homeobox domain DUF2722 PF10846.6 001302427.1_39723001_1 - 0.00014 20.8 5.2 0.00022 20.2 5.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) HTH_31 PF13560.4 001302427.1_39723001_1 - 0.00075 19.7 0.1 0.086 13.1 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain Homeobox_KN PF05920.9 001302427.1_39723001_1 - 0.0077 16.0 0.1 0.033 13.9 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain SARAF PF06682.10 001302427.1_39723001_1 - 0.056 13.0 13.7 2.2 7.7 0.1 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.6 001302427.1_39723001_1 - 0.11 11.9 19.6 0.098 12.1 18.1 1.6 2 0 0 2 2 2 0 Spt20 family Pex14_N PF04695.11 001302427.1_39723001_1 - 0.19 12.3 12.3 0.26 11.9 6.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.15 001302427.1_39723001_1 - 0.43 9.1 1.1 0.6 8.7 1.1 1.2 1 0 0 1 1 1 0 Presenilin Suf PF05843.12 001302427.1_39723001_1 - 0.78 9.5 7.3 1.5 8.6 7.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.3 001302427.1_39723001_1 - 1.2 10.0 5.6 2.8 8.8 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Med15 PF09606.8 001302427.1_39723001_1 - 1.7 7.1 38.9 2.4 6.6 38.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med3 PF11593.6 001302427.1_39723001_1 - 2 7.4 12.3 3.1 6.8 12.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UPF0560 PF10577.7 001302427.1_39723001_1 - 4.5 5.5 8.4 6.3 5.0 8.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 GSHPx PF00255.17 001115157.1_39724001_2 - 1.6e-37 127.3 0.1 2.4e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase DUF3449 PF11931.6 001246453.1_39724001_3 - 4.3e-77 257.9 3.4 4.3e-77 257.9 3.4 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.4 001246453.1_39724001_3 - 3.3e-28 97.0 2.3 6.9e-28 95.9 2.3 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.3 001246453.1_39724001_3 - 5.1e-23 81.2 6.7 5.1e-23 81.2 6.7 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.6 001246453.1_39724001_3 - 9e-16 57.3 1.2 2e-15 56.2 1.2 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain ARL2_Bind_BART PF11527.6 001246458.1_39724001_2 - 2.3e-32 111.4 7.8 3.4e-32 110.9 7.8 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Dynein_light PF01221.16 001242621.2_39723001_2 - 1.7e-42 143.4 2.1 3.4e-42 142.5 2.1 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 Integrin_alpha2 PF08441.10 001194934.1_39728001_1 - 2.7e-42 145.1 2.9 4e-42 144.5 2.9 1.2 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.26 001194934.1_39728001_1 - 3.3e-39 134.8 0.1 5.5e-39 134.1 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.21 001194934.1_39728001_1 - 5.1e-20 71.1 2.4 9.2e-08 31.9 1.6 3.8 3 0 0 3 3 3 3 FG-GAP repeat VWA_2 PF13519.4 001194934.1_39728001_1 - 7.4e-14 52.2 0.0 1.8e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_alpha PF00357.18 001194934.1_39728001_1 - 7.9e-06 25.3 0.6 1.6e-05 24.4 0.6 1.5 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region VCBS PF13517.4 001194934.1_39728001_1 - 6.6e-05 23.3 0.4 0.19 12.2 0.2 3.5 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Copine PF07002.14 001194934.1_39728001_1 - 0.031 13.6 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Copine FG-GAP_2 PF14312.4 001194934.1_39728001_1 - 0.044 13.9 7.7 0.54 10.4 0.1 3.7 4 0 0 4 4 4 0 FG-GAP repeat EGF PF00008.25 001242623.1_39722001_2 - 0.0014 18.7 4.4 0.0014 18.7 4.4 1.7 2 0 0 2 2 2 1 EGF-like domain DUF4514 PF14986.4 001242623.1_39722001_2 - 0.0054 16.6 1.5 0.0059 16.4 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4514) EGF_2 PF07974.11 001242623.1_39722001_2 - 0.044 14.0 2.8 0.12 12.6 2.8 1.8 1 1 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.22 001242623.1_39722001_2 - 0.26 11.3 3.6 0.48 10.5 3.6 1.4 1 0 0 1 1 1 0 Laminin EGF domain SKG6 PF08693.8 001242623.1_39722001_2 - 0.81 9.0 3.2 0.31 10.3 0.6 1.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SH3_1 PF00018.26 001246617.1_39724001_2 - 5.5e-34 115.4 0.9 9.7e-16 57.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 001246617.1_39724001_2 - 1.6e-31 107.8 0.2 1.7e-14 53.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.15 001246617.1_39724001_2 - 4.7e-27 93.3 0.0 4.8e-15 54.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.22 001246617.1_39724001_2 - 3.5e-24 84.5 0.0 6.1e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.4 001246617.1_39724001_2 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 SH2 domain hSH3 PF14603.4 001246617.1_39724001_2 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 Helically-extended SH3 domain SH3_3 PF08239.9 001246617.1_39724001_2 - 0.097 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF5093 PF17011.3 001246617.1_39724001_2 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) Cys_knot PF00007.20 001280311.1_39725001_3 - 5.4e-16 58.7 11.0 5.4e-16 58.7 11.0 3.4 3 0 0 3 3 3 1 Cystine-knot domain VWC PF00093.16 001280311.1_39725001_3 - 2.2e-10 40.6 9.2 2.2e-10 40.6 9.2 5.2 5 3 0 5 5 5 1 von Willebrand factor type C domain IGFBP PF00219.16 001280311.1_39725001_3 - 7.1e-10 39.2 20.7 7.1e-10 39.2 20.7 5.0 4 2 1 5 5 5 1 Insulin-like growth factor binding protein TSP_1 PF00090.17 001280311.1_39725001_3 - 7.6e-05 22.7 7.8 7.6e-05 22.7 7.8 2.8 3 0 0 3 3 3 1 Thrombospondin type 1 domain UBX PF00789.18 001246510.1_39724001_3 - 2.7e-20 72.2 0.1 5.1e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.4 001246510.1_39724001_3 - 0.12 12.5 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin-like SID-1_RNA_chan PF13965.4 001246510.1_39724001_3 - 6.9 4.9 7.7 11 4.2 7.0 1.6 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Ribosomal_L7Ae PF01248.24 001246603.2_39722001_2 - 4.4e-24 83.9 0.7 1.4e-23 82.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2362 PF10154.7 001280362.1_39725001_2 - 1.2e-215 717.1 8.9 1.5e-215 716.8 8.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) CSD PF00313.20 001280274.1_39724001_1 - 6.2e-26 89.9 0.5 1.1e-25 89.1 0.5 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.9 001280274.1_39724001_1 - 0.031 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain Herpes_LMP1 PF05297.9 001280274.1_39724001_1 - 0.035 13.2 2.1 0.059 12.4 2.1 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) UBA PF00627.29 001246491.1_39725001_2 - 1.1e-11 44.2 0.6 1.9e-11 43.5 0.6 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.20 001246491.1_39725001_2 - 0.035 13.9 3.1 0.062 13.1 3.1 1.4 1 0 0 1 1 1 0 Rhomboid family DER1 PF04511.13 001246491.1_39725001_2 - 0.083 12.4 5.5 0.14 11.7 5.5 1.3 1 0 0 1 1 1 0 Der1-like family Cpn60_TCP1 PF00118.22 001280161.1_39725001_3 - 3.3e-155 517.3 16.8 3.7e-155 517.1 16.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family APOBEC_N PF08210.9 001251910.1_39723001_3 - 4.4e-58 196.0 4.0 5.4e-58 195.7 4.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001251910.1_39723001_3 - 1.4e-32 111.3 0.2 3e-32 110.3 0.2 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001251910.1_39723001_3 - 0.0034 17.1 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.4 001251910.1_39723001_3 - 0.027 14.4 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases EF1G PF00647.17 001302424.1_39724001_2 - 5.7e-52 174.1 0.4 1e-51 173.4 0.4 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.18 001302424.1_39724001_2 - 1.9e-23 82.5 0.0 8.8e-23 80.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001302424.1_39724001_2 - 5.8e-19 68.0 0.0 5.8e-19 68.0 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.4 001302424.1_39724001_2 - 1.2e-09 37.8 0.0 3.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001302424.1_39724001_2 - 6.1e-07 29.4 0.1 2.7e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001302424.1_39724001_2 - 1.5e-06 28.3 0.0 5e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.4 001302424.1_39724001_2 - 0.0019 18.4 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain IF-2B PF01008.15 001280176.1_39724001_1 - 1.1e-90 303.6 0.0 1.4e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family WD40 PF00400.30 001280241.1_39724001_2 - 1.8e-20 72.7 10.3 4.9e-07 30.2 1.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat FYVE PF01363.19 001280241.1_39724001_2 - 7e-14 51.6 7.6 1.5e-13 50.6 7.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger ANAPC4_WD40 PF12894.5 001280241.1_39724001_2 - 4.3e-05 23.6 0.1 0.16 12.1 0.0 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.9 001280241.1_39724001_2 - 0.0043 15.8 0.0 0.84 8.2 0.0 3.0 3 1 0 3 3 3 2 Nup133 N terminal like FYVE_2 PF02318.14 001280241.1_39724001_2 - 0.07 13.2 4.3 0.16 12.1 4.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger MORN PF02493.18 001246561.1_39725001_1 - 1.6e-13 49.6 9.4 1.4e-07 30.9 0.2 5.0 5 0 0 5 5 5 3 MORN repeat DEAD PF00270.27 001246548.1_39724001_2 - 7.4e-48 162.5 0.1 1.1e-47 161.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001246548.1_39724001_2 - 6e-31 107.0 0.2 3.9e-30 104.3 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.13 001246548.1_39724001_2 - 8.2e-06 25.8 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SPAN-X PF07458.10 001042629.1_39721001_1 - 6.2e-46 154.6 9.3 6.2e-46 154.6 9.3 1.3 2 0 0 2 2 2 1 Sperm protein associated with nucleus, mapped to X chromosome Kinesin PF00225.21 001280277.1_39725001_1 - 5.6e-93 311.4 0.0 9e-93 310.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.3 001280277.1_39725001_1 - 9.7e-21 74.1 0.0 1.9e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.5 001280277.1_39725001_1 - 2.1e-11 43.8 0.0 6.7e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_6 PF14579.4 001280277.1_39725001_1 - 0.00037 20.5 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif PsbU PF06514.9 001280277.1_39725001_1 - 0.04 13.8 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_5 PF14520.4 001280277.1_39725001_1 - 0.099 13.2 0.1 2.8 8.5 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain Pkinase_Tyr PF07714.15 001280185.1_39725001_2 - 3e-25 88.9 0.6 5.7e-25 87.9 0.6 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.23 001280185.1_39725001_2 - 3.2e-24 85.6 1.3 3.2e-24 85.6 1.3 1.9 2 1 0 2 2 2 1 Protein kinase domain TPR_11 PF13414.4 001246600.1_39725001_3 - 0.0042 16.6 0.0 0.2 11.2 0.0 2.9 3 0 0 3 3 3 1 TPR repeat A_deamin PF02137.16 001246556.1_39725001_1 - 2.1e-90 303.3 0.1 3e-90 302.9 0.1 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.24 001246556.1_39725001_1 - 1.8e-11 44.4 0.2 2.1e-10 41.0 0.0 2.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif DP PF08781.8 001280410.1_39724001_3 - 3.4e-61 205.0 2.9 6.3e-61 204.2 2.9 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.18 001280410.1_39724001_3 - 2.2e-26 91.5 0.3 4.5e-26 90.5 0.3 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain FliD_C PF07195.10 001280410.1_39724001_3 - 0.25 10.6 4.7 0.33 10.2 2.0 2.0 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Vps26 PF03643.13 001329612.1_39726001_2 - 1.3e-133 444.1 5.1 1.6e-133 443.8 5.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 zf-H2C2_2 PF13465.4 001302762.1_39722001_1 - 7.5e-14 51.3 24.7 6.7e-10 38.8 0.3 4.9 4 1 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.24 001302762.1_39722001_1 - 2.1e-13 49.7 30.6 0.0003 20.9 0.8 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001302762.1_39722001_1 - 8.8e-10 38.4 29.1 0.0033 18.0 1.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger FYVE PF01363.19 001302762.1_39722001_1 - 0.00047 20.1 19.1 0.008 16.2 3.6 2.5 1 1 1 2 2 2 2 FYVE zinc finger zf-C2H2_jaz PF12171.6 001302762.1_39722001_1 - 0.036 14.3 9.2 5 7.4 1.5 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001302762.1_39722001_1 - 0.041 13.5 0.8 0.041 13.5 0.8 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.5 001302762.1_39722001_1 - 0.078 13.2 0.4 0.078 13.2 0.4 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.4 001302762.1_39722001_1 - 0.09 12.4 1.1 0.09 12.4 1.1 4.9 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.3 001302762.1_39722001_1 - 0.65 10.6 7.4 3.4 8.4 4.3 2.5 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_2 PF12756.5 001302762.1_39722001_1 - 1.4 9.1 14.3 3.8 7.8 2.5 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) NinF PF05810.10 001302762.1_39722001_1 - 6.5 6.6 6.3 39 4.1 0.0 3.1 3 0 0 3 3 3 0 NinF protein zf-C2HE PF16278.3 001302762.1_39722001_1 - 6.6 7.1 9.4 13 6.2 0.1 3.3 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger TUDOR PF00567.22 001280508.1_39727001_3 - 3.6e-22 78.5 0.0 6.1e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.27 001280508.1_39727001_3 - 8.7e-11 41.4 0.0 1.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 KH domain RII_binding_1 PF10522.7 001280508.1_39727001_3 - 2.5e-05 23.9 2.2 5.7e-05 22.7 2.2 1.7 1 0 0 1 1 1 1 RII binding domain Agenet PF05641.10 001280508.1_39727001_3 - 0.002 18.5 1.6 0.0044 17.3 0.4 2.2 2 0 0 2 2 2 1 Agenet domain Gar1 PF04410.12 001279872.1_39724001_2 - 2.9e-44 150.4 0.8 4.7e-44 149.7 0.8 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region SR-25 PF10500.7 001279872.1_39724001_2 - 1.8 8.0 25.2 0.075 12.5 13.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EF-hand_4 PF12763.5 001246633.1_39728001_2 - 1.7e-17 63.2 0.0 3.4e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.3 001246633.1_39728001_2 - 1e-15 57.2 1.0 1e-15 57.2 1.0 2.0 2 0 0 2 2 2 1 N-terminal EH-domain containing protein Dynamin_N PF00350.21 001246633.1_39728001_2 - 3.4e-12 46.6 0.0 1.2e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.21 001246633.1_39728001_2 - 5.6e-07 29.5 0.0 9.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.30 001246633.1_39728001_2 - 0.03 13.7 0.0 0.073 12.5 0.0 1.6 1 0 0 1 1 1 0 EF hand Na_sulph_symp PF00939.17 001280154.1_39724001_1 - 1.7e-128 429.5 26.7 2.1e-128 429.2 26.7 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.14 001280154.1_39724001_1 - 4.1e-39 134.4 26.4 1.9e-22 79.7 0.1 3.3 2 2 1 3 3 3 3 Citrate transporter Pex2_Pex12 PF04757.12 001280222.1_39724001_1 - 1.1e-35 123.1 1.0 1.6e-35 122.6 1.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.23 001280222.1_39724001_1 - 9.4e-07 28.5 8.1 9.4e-07 28.5 8.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.4 001280222.1_39724001_1 - 2.6e-05 23.9 3.5 5.1e-05 22.9 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001280222.1_39724001_1 - 0.00061 19.5 5.9 0.0013 18.5 5.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.4 001280222.1_39724001_1 - 0.018 15.0 10.9 0.049 13.7 10.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.4 001280222.1_39724001_1 - 0.073 13.0 8.6 0.12 12.3 7.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zinc-ribbons_6 PF07191.10 001280222.1_39724001_1 - 0.19 11.6 2.2 0.41 10.5 2.2 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-RING_6 PF14835.4 001280222.1_39724001_1 - 0.23 11.2 3.5 1 9.1 3.5 2.1 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.4 001280222.1_39724001_1 - 0.27 11.1 12.7 0.06 13.2 8.2 2.3 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.4 001280222.1_39724001_1 - 0.4 10.8 8.9 1.2 9.4 8.9 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.4 001280222.1_39724001_1 - 1.1 9.0 14.8 0.19 11.5 9.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CKS PF01111.17 001252546.1_39722001_1 - 7e-38 128.6 1.2 1e-37 128.1 1.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Mito_carr PF00153.25 001246618.1_39724001_2 - 3.5e-66 219.0 0.8 8.4e-22 76.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LIM PF00412.20 001246370.1_39724001_1 - 5.2e-44 148.2 75.7 7.9e-12 45.1 5.3 5.3 5 0 0 5 5 5 5 LIM domain PPP1R32 PF15691.3 001302423.1_39724001_3 - 1.4e-197 656.7 3.1 1.7e-197 656.5 3.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 32 Pkinase PF00069.23 001246512.1_39724001_1 - 1.4e-38 132.6 0.0 1.9e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001246512.1_39724001_1 - 1.1e-33 116.5 0.0 1.5e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PRAS PF15798.3 001246387.1_39725001_2 - 9.7e-49 164.9 0.7 1.7e-48 164.1 0.7 1.4 1 0 0 1 1 1 1 Proline-rich AKT1 substrate 1 YtxH PF12732.5 001280488.1_39726001_3 - 0.023 15.1 3.1 0.023 15.1 3.1 3.5 3 1 0 3 3 3 0 YtxH-like protein 2-oxoacid_dh PF00198.21 001280073.1_39725001_1 - 4.3e-73 245.5 0.0 5.5e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.20 001280073.1_39725001_1 - 6.7e-19 67.4 0.4 1.5e-18 66.3 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.15 001280073.1_39725001_1 - 9.3e-07 29.0 0.0 1.9e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.4 001280073.1_39725001_1 - 0.0089 15.7 0.0 0.059 13.1 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like Cyt-b5 PF00173.26 001242609.1_39729001_1 - 7.6e-24 83.5 0.0 1.2e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M16 PF00675.18 001279889.1_39724001_3 - 1e-56 190.9 0.2 1.7e-56 190.2 0.2 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001279889.1_39724001_3 - 1.4e-37 129.3 0.0 1.1e-36 126.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain HEAT PF02985.20 001279833.1_39727001_1 - 2.1e-17 61.6 8.8 5.6e-06 26.0 0.0 9.1 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.4 001279833.1_39727001_1 - 1e-16 60.9 3.6 1.6e-11 44.3 0.0 6.5 7 1 1 8 8 8 2 HEAT-like repeat IBN_N PF03810.17 001279833.1_39727001_1 - 5.3e-12 45.3 0.7 3.5e-11 42.7 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.4 001279833.1_39727001_1 - 1.5e-09 37.9 0.2 2.7e-05 24.3 0.0 5.0 2 2 2 4 4 4 2 HEAT repeats Arm PF00514.21 001279833.1_39727001_1 - 3e-09 36.4 1.6 0.00066 19.5 0.0 4.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.5 001279833.1_39727001_1 - 1.4e-06 28.3 0.6 0.0022 17.9 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.6 001279833.1_39727001_1 - 4e-05 23.2 2.3 0.52 9.7 0.0 4.1 3 1 1 4 4 4 2 CLASP N terminal V-ATPase_H_C PF11698.6 001279833.1_39727001_1 - 0.19 11.7 4.4 0.79 9.7 0.3 3.1 2 0 0 2 2 2 0 V-ATPase subunit H Myosin_N PF02736.17 001246444.1_39724001_3 - 5.3e-15 54.8 4.5 8.5e-15 54.2 4.5 1.3 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_head PF00063.19 001246444.1_39724001_3 - 1.5e-06 26.7 0.0 1.9e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Tubulin PF00091.23 001280288.1_39725001_1 - 2.5e-66 223.5 0.0 3.5e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001280288.1_39725001_1 - 2.2e-50 170.0 0.0 3.3e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001280288.1_39725001_1 - 0.0092 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Phage_DNA_bind PF02303.15 001280288.1_39725001_1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Helix-destabilising protein AraC_binding PF02311.17 001280357.1_39722001_1 - 0.059 13.1 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Metallothio PF00131.18 001301278.1_39721001_2 - 2.4e-18 65.9 62.1 3.3e-18 65.4 62.1 1.2 1 0 0 1 1 1 1 Metallothionein ELO PF01151.16 001246625.1_39726001_3 - 7.9e-64 215.4 23.7 1.1e-63 214.9 23.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_M14 PF00246.22 001302411.1_39725001_1 - 5e-73 246.3 0.0 7.1e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Fz PF01392.20 001302411.1_39725001_1 - 3e-20 72.9 1.4 5.5e-20 72.0 1.4 1.4 1 0 0 1 1 1 1 Fz domain CarboxypepD_reg PF13620.4 001302411.1_39725001_1 - 5.5e-12 45.6 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.4 001302411.1_39725001_1 - 0.00016 21.5 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.12 001302411.1_39725001_1 - 0.00042 19.4 0.0 0.0048 15.9 0.1 2.2 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family TBP PF00352.19 001099292.1_39722001_1 - 1.4e-45 153.0 0.3 6.5e-23 80.4 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.6 001099292.1_39722001_1 - 0.029 14.3 0.0 0.08 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) 7tm_4 PF13853.4 001280384.1_39724001_1 - 3.8e-41 141.5 9.8 5.3e-41 141.0 9.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001280384.1_39724001_1 - 2.2e-25 89.3 6.4 2.5e-25 89.1 6.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MAGE_N PF12440.6 001280464.1_39724001_1 - 5.8e-24 84.5 9.2 1e-23 83.7 9.2 1.4 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal MAGE PF01454.17 001280464.1_39724001_1 - 7.1e-17 61.7 0.0 6.7e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 MAGE family DUF3098 PF11297.6 001280464.1_39724001_1 - 0.009 15.5 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3098) Tektin PF03148.12 001246543.1_39724001_3 - 1.5e-148 494.5 31.1 1.8e-148 494.3 31.1 1.0 1 0 0 1 1 1 1 Tektin family MiaE_2 PF13794.4 001246543.1_39724001_3 - 0.031 13.9 0.5 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Baculo_PEP_C PF04513.10 001246543.1_39724001_3 - 0.78 9.7 11.5 1.6 8.7 6.1 2.9 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus JIP_LZII PF16471.3 001246543.1_39724001_3 - 1 9.5 10.5 8.6 6.5 0.3 4.1 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF948 PF06103.9 001246543.1_39724001_3 - 9.2 6.5 11.4 3.4 7.9 0.3 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2452 PF10504.7 001243098.1_39722001_2 - 3.5e-73 244.1 0.0 4.5e-73 243.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) DUF3337 PF11816.6 001280519.1_39726001_1 - 6.1e-47 159.4 0.1 2.1e-46 157.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.30 001280519.1_39726001_1 - 2.9e-28 97.4 8.4 6.3e-05 23.5 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280519.1_39726001_1 - 1e-06 28.8 2.4 0.053 13.7 0.2 4.0 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.9 001280519.1_39726001_1 - 0.0081 14.8 0.5 0.75 8.4 0.0 3.0 1 1 2 3 3 3 1 Nup133 N terminal like RAWUL PF16207.3 001280519.1_39726001_1 - 0.0085 16.6 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like WD40_like PF17005.3 001280519.1_39726001_1 - 0.026 13.7 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain Nup160 PF11715.6 001280519.1_39726001_1 - 0.12 10.8 6.6 1.3 7.4 0.2 3.8 2 1 2 4 4 4 0 Nucleoporin Nup120/160 tRNA_int_endo PF01974.15 001280291.1_39725001_3 - 1.7e-18 66.3 0.0 3.6e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.12 001280291.1_39725001_3 - 3.9e-18 64.8 0.8 1.1e-12 47.3 0.3 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain PP2C PF00481.19 001246455.1_39725001_3 - 1.5e-74 250.8 0.3 3.6e-57 193.8 0.5 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.4 001246455.1_39725001_3 - 0.016 14.7 0.0 0.059 12.9 0.0 1.8 2 1 0 2 2 2 0 Protein phosphatase 2C ArgoL1 PF08699.8 001246455.1_39725001_3 - 0.12 11.9 0.9 0.45 10.0 0.2 2.3 3 0 0 3 3 3 0 Argonaute linker 1 domain zf-C3HC4_3 PF13920.4 001280376.1_39724001_1 - 1.6e-11 43.8 4.4 1.6e-11 43.8 4.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.16 001280376.1_39724001_1 - 9.4e-09 34.3 6.2 9.4e-09 34.3 6.2 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others SWIB PF02201.16 001280376.1_39724001_1 - 2.1e-06 27.4 0.0 4.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Prok-RING_4 PF14447.4 001280376.1_39724001_1 - 0.00088 19.0 5.1 0.0036 17.0 5.1 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Cript PF10235.7 001280376.1_39724001_1 - 0.0085 16.5 0.5 0.0085 16.5 0.5 2.7 3 0 0 3 3 3 1 Microtubule-associated protein CRIPT Cytochrom_c3_2 PF14537.4 001280376.1_39724001_1 - 0.062 13.6 0.4 0.062 13.6 0.4 2.7 2 0 0 2 2 2 0 Cytochrome c3 DZR PF12773.5 001280376.1_39724001_1 - 0.48 10.4 14.2 1.3 9.0 2.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-FLZ PF04570.12 001280376.1_39724001_1 - 3.6 7.0 8.5 23 4.5 0.8 3.6 2 1 1 3 3 3 0 zinc-finger of the FCS-type, C2-C2 zf-RING_2 PF13639.4 001280376.1_39724001_1 - 4.7 7.4 14.7 0.073 13.2 5.2 2.6 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.4 001280376.1_39724001_1 - 7.5 6.4 9.5 1.2 8.9 4.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_15 PF17032.3 001280376.1_39724001_1 - 8.8 7.0 13.4 0.57 10.8 0.9 3.1 3 0 0 3 3 2 0 zinc-ribbon family Pkinase PF00069.23 001280201.1_39725001_3 - 4.8e-36 124.3 0.0 7.7e-36 123.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280201.1_39725001_3 - 3.5e-28 98.5 0.0 3e-25 88.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.4 001280201.1_39725001_3 - 0.00091 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ASXH PF13919.4 001280201.1_39725001_3 - 0.069 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Asx homology domain Ig_2 PF13895.4 001009044.1_39724001_1 - 6.7e-34 115.9 0.8 5e-15 55.5 0.1 4.2 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.4 001009044.1_39724001_1 - 7.3e-29 100.1 1.4 3.3e-07 30.7 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.23 001009044.1_39724001_1 - 1.5e-21 76.2 0.1 2e-06 27.7 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.15 001009044.1_39724001_1 - 1.5e-06 28.2 6.2 0.45 10.6 0.2 6.6 4 3 1 5 5 5 1 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001009044.1_39724001_1 - 0.0017 18.2 0.0 1.3 9.0 0.0 3.4 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain I-set PF07679.14 001009044.1_39724001_1 - 0.0026 17.7 0.0 6.2 6.8 0.0 3.8 3 1 0 3 3 3 1 Immunoglobulin I-set domain Ig_4 PF16680.3 001009044.1_39724001_1 - 0.045 14.0 3.2 7.9 6.8 0.1 4.4 4 2 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain SQS_PSY PF00494.17 001280152.1_39724001_3 - 2.3e-41 141.9 0.0 2.9e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Octopine_DH PF02317.15 001280152.1_39724001_3 - 0.044 13.7 0.3 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain PA28_beta PF02252.16 001251895.3_39727001_3 - 2.4e-64 215.2 3.4 3.3e-64 214.8 3.4 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.16 001251895.3_39727001_3 - 1.9e-23 82.3 1.9 3.3e-23 81.5 1.9 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Lung_7-TM_R PF06814.11 001243054.1_39726001_1 - 1.5e-84 283.5 19.9 2e-84 283.1 19.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SPT6_acidic PF14632.4 001243054.1_39726001_1 - 0.075 13.5 1.2 0.15 12.5 1.2 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 APOBEC_N PF08210.9 001142606.1_39722001_1 - 1e-34 119.9 2.0 1.1e-34 119.8 2.0 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001142606.1_39722001_1 - 2.5e-26 91.3 0.0 4.1e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001142606.1_39722001_1 - 3.4e-05 23.5 0.6 5.5e-05 22.8 0.6 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.4 001142606.1_39722001_1 - 0.1 12.2 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 MafB19-like deaminase TINF2_N PF14973.4 001246606.1_39724001_2 - 1.9e-47 161.2 1.5 2.8e-47 160.6 1.5 1.3 1 0 0 1 1 1 1 TERF1-interacting nuclear factor 2 N-terminus CHZ PF09649.8 001280458.1_39724001_1 - 4.2e-10 38.8 0.2 1.5e-09 37.0 0.2 2.1 1 0 0 1 1 1 1 Histone chaperone domain CHZ B12D PF06522.9 001244677.1_39722001_1 - 8.2e-22 76.7 0.1 1.2e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit MAPEG PF01124.16 001251941.2_39722001_2 - 2.6e-25 88.7 0.1 3.3e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 MAPEG family Trypsin_2 PF13365.4 001280145.1_39724001_3 - 6.1e-31 108.2 1.4 1.1e-30 107.4 1.4 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.24 001280145.1_39724001_3 - 6e-13 49.0 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.4 001280145.1_39724001_3 - 8.4e-09 35.5 0.0 2.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.22 001280145.1_39724001_3 - 1.3e-06 28.5 0.0 3.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.7 001280145.1_39724001_3 - 5.2e-05 22.0 0.5 0.064 11.8 0.2 2.1 2 0 0 2 2 2 2 Peptidase S46 GRASP55_65 PF04495.12 001280145.1_39724001_3 - 0.00098 19.3 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.4 001280145.1_39724001_3 - 0.02 14.7 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain RmlD_sub_bind PF04321.15 001246566.1_39724001_1 - 2.4e-85 286.0 0.0 2.9e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.19 001246566.1_39724001_1 - 4.3e-23 81.9 0.0 5.9e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.3 001246566.1_39724001_1 - 7.8e-09 35.2 0.1 1.4e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.13 001246566.1_39724001_1 - 6.7e-08 31.9 0.4 9.3e-06 24.8 0.4 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.10 001246566.1_39724001_1 - 0.0018 17.4 0.0 0.11 11.5 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein DapB_N PF01113.18 001246566.1_39724001_1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus E1_DerP2_DerF2 PF02221.13 001130474.1_39721001_1 - 1.7e-14 54.3 0.2 2e-14 54.0 0.2 1.1 1 0 0 1 1 1 1 ML domain Kinesin PF00225.21 001246521.1_39725001_1 - 2.6e-121 404.5 0.1 5.8e-121 403.3 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.3 001246521.1_39725001_1 - 5.5e-27 94.4 0.1 3.1e-26 92.0 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.4 001246521.1_39725001_1 - 0.025 14.7 4.8 1.6 8.9 0.0 3.3 2 1 0 2 2 2 0 AAA domain DUF1492 PF07374.9 001246521.1_39725001_1 - 2.9 8.0 8.8 1.9 8.5 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) TPR_6 PF13174.4 001280517.1_39727001_3 - 0.00022 21.5 0.9 2.4 8.9 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat HEAT_2 PF13646.4 001280517.1_39727001_3 - 0.00098 19.3 5.4 0.15 12.3 0.1 4.8 5 1 0 5 5 5 1 HEAT repeats DUF3453 PF11935.6 001280517.1_39727001_3 - 0.02 14.4 4.7 0.16 11.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3453) FANCI_S2 PF14676.4 001280517.1_39727001_3 - 0.16 12.0 5.4 0.32 11.1 0.5 3.0 2 0 0 2 2 2 0 FANCI solenoid 2 SPG48 PF14764.4 001280517.1_39727001_3 - 0.3 11.4 7.0 0.3 11.4 0.4 3.6 3 1 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking IL13 PF03487.11 001280517.1_39727001_3 - 1.7 8.4 5.2 11 5.8 0.2 3.9 4 1 1 5 5 5 0 Interleukin-13 CytochromB561_N PF09786.7 001280210.2_39724001_2 - 4.1e-160 534.4 0.4 4.9e-160 534.2 0.4 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal NPCC PF08058.9 001280210.2_39724001_2 - 0.016 15.1 0.5 0.056 13.4 0.0 2.0 2 0 0 2 2 2 0 Nuclear pore complex component EMI PF07546.11 001251914.2_39726001_1 - 0.54 10.9 4.7 18 6.0 0.3 2.8 2 0 0 2 2 2 0 EMI domain DUF2781 PF10914.6 001251914.2_39726001_2 - 6.8e-46 156.2 8.0 1.1e-45 155.5 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) 7tm_1 PF00001.19 001246599.2_39724001_1 - 3.2e-63 213.4 19.5 4.9e-63 212.7 19.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001246599.2_39724001_1 - 4.5e-18 65.4 19.7 5.8e-18 65.1 19.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.7 001246599.2_39724001_1 - 3.9e-10 39.4 7.8 3.9e-10 39.4 7.8 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.7 001246599.2_39724001_1 - 5.4e-08 32.3 18.8 5.4e-08 32.3 18.8 1.9 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx FtsK_4TM PF13491.4 001246599.2_39724001_1 - 0.0088 15.6 2.3 0.0088 15.6 2.3 2.1 1 1 1 2 2 2 1 4TM region of DNA translocase FtsK/SpoIIIE Somatostatin PF03002.13 001204893.1_39723001_3 - 1.4e-09 37.6 5.9 2.7e-09 36.7 5.9 1.5 1 0 0 1 1 1 1 Somatostatin/Cortistatin family zf-H2C2_2 PF13465.4 001246438.1_39725001_2 - 1.6e-46 154.6 64.2 7.6e-09 35.5 1.2 9.4 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.24 001246438.1_39725001_2 - 1.9e-38 128.7 76.3 9.3e-06 25.7 4.1 8.8 8 0 0 8 8 8 7 Zinc finger, C2H2 type KRAB PF01352.25 001246438.1_39725001_2 - 2.1e-24 84.8 0.0 3.9e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001246438.1_39725001_2 - 1.1e-18 66.1 62.1 0.0077 16.8 0.4 8.0 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001246438.1_39725001_2 - 3.4e-09 36.3 50.6 0.0023 17.7 0.4 7.7 7 0 0 7 7 7 6 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001246438.1_39725001_2 - 1.1e-05 25.3 34.3 0.0035 17.3 1.5 5.8 2 1 3 6 6 6 4 Zinc ribbon domain zf-trcl PF13451.4 001246438.1_39725001_2 - 7.6e-05 22.4 28.6 0.19 11.5 0.2 7.3 7 0 0 7 7 7 3 Probable zinc-ribbon domain zf-C2H2_jaz PF12171.6 001246438.1_39725001_2 - 0.0064 16.6 35.9 0.18 12.0 0.9 7.2 7 0 0 7 7 6 3 Zinc-finger double-stranded RNA-binding XPA_N PF01286.16 001246438.1_39725001_2 - 0.039 13.8 27.3 2.5 8.1 0.4 7.3 7 0 0 7 7 7 0 XPA protein N-terminal zf-AN1 PF01428.14 001246438.1_39725001_2 - 0.42 10.7 41.3 1.9 8.6 4.1 7.5 5 2 2 7 7 7 0 AN1-like Zinc finger zinc_ribbon_15 PF17032.3 001246438.1_39725001_2 - 0.46 11.1 29.5 0.56 10.9 2.1 4.8 1 1 5 6 6 6 0 zinc-ribbon family zf-C2H2_11 PF16622.3 001246438.1_39725001_2 - 0.65 9.7 47.3 0.32 10.6 0.1 7.4 7 0 0 7 7 7 0 zinc-finger C2H2-type FYDLN_acid PF09538.8 001246438.1_39725001_2 - 2 9.0 14.4 39 4.9 0.1 6.1 2 1 3 6 6 6 0 Protein of unknown function (FYDLN_acid) DUF3268 PF11672.6 001246438.1_39725001_2 - 3.4 7.9 21.3 0.83 9.9 0.6 3.6 4 0 0 4 4 3 0 zinc-finger-containing domain zf-C2HE PF16278.3 001246438.1_39725001_2 - 6 7.3 40.9 0.57 10.5 0.5 7.2 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger Connexin PF00029.17 001279917.1_39725001_3 - 4.1e-85 285.0 8.6 4.1e-85 285.0 8.6 1.5 2 0 0 2 2 2 1 Connexin Ribosomal_L6e PF01159.17 001246573.1_39724001_2 - 4.4e-44 149.3 1.5 4.4e-44 149.3 1.5 2.2 3 0 0 3 3 3 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.13 001246573.1_39724001_2 - 6.4e-35 119.0 13.7 6.4e-35 119.0 13.7 2.2 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain Far-17a_AIG1 PF04750.12 001251896.2_39724001_1 - 7.2e-63 211.4 13.5 9.6e-63 211.0 13.5 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein RNA_pol_I_A49 PF06870.10 001279994.1_39724001_2 - 5.7e-108 361.1 0.3 8.2e-108 360.6 0.3 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF4239 PF14023.4 001279994.1_39724001_2 - 0.08 12.6 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Rad21_Rec8_N PF04825.11 001280460.1_39725001_1 - 1.8e-40 137.4 0.0 3.3e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.14 001280460.1_39725001_1 - 2.5e-20 71.4 0.2 1.5e-19 68.9 0.1 2.3 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.12 001280460.1_39725001_1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Segregation and condensation protein ScpA CDC45 PF02724.12 001280460.1_39725001_1 - 0.87 7.7 3.9 1.7 6.7 3.9 1.4 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.11 001280460.1_39725001_1 - 0.93 7.4 7.4 1.6 6.6 7.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF773 PF05600.10 001279879.1_39724001_2 - 1.8e-182 607.5 2.2 2.2e-182 607.2 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF773) Fib_alpha PF08702.8 001279879.1_39724001_2 - 5.7 7.0 9.5 6.4 6.8 2.9 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PAP2_C PF14360.4 001280493.1_39724001_2 - 6.7e-26 90.5 13.2 6.7e-26 90.5 13.2 2.2 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.19 001280493.1_39724001_2 - 1.9e-06 27.6 10.2 4.1e-06 26.5 9.7 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.4 001280493.1_39724001_2 - 0.077 12.5 11.0 0.05 13.2 6.8 2.3 2 0 0 2 2 2 0 PAP2 superfamily Tap-RNA_bind PF09162.8 001280400.1_39725001_3 - 3.6e-39 132.4 0.2 7.2e-39 131.4 0.2 1.5 1 0 0 1 1 1 1 Tap, RNA-binding NTF2 PF02136.18 001280400.1_39725001_3 - 5.1e-28 97.9 0.0 8.9e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain TAP_C PF03943.11 001280400.1_39725001_3 - 3.4e-25 87.2 0.9 6.1e-25 86.4 0.9 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.5 001280400.1_39725001_3 - 6.9e-05 23.0 9.1 0.0012 19.1 1.3 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001280400.1_39725001_3 - 0.00025 20.6 5.6 0.00025 20.6 5.6 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.31 001280400.1_39725001_3 - 0.016 15.4 5.2 4 8.2 0.2 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_9 PF14580.4 001280400.1_39725001_3 - 0.019 14.3 0.2 0.035 13.5 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.4 001280400.1_39725001_3 - 0.18 11.8 1.7 2.1 8.5 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeat RRM_1 PF00076.20 001195547.1_39722001_2 - 1.3e-33 114.5 0.0 3.9e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001195547.1_39722001_2 - 8.1e-05 22.4 0.0 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.3 001195547.1_39722001_2 - 0.00052 19.7 0.0 0.0012 18.5 0.0 1.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.9 001195547.1_39722001_2 - 0.0011 18.8 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.3 001195547.1_39722001_2 - 0.0046 16.9 0.0 0.024 14.6 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif DDE_Tnp_1 PF01609.19 001195547.1_39722001_2 - 0.0054 16.3 0.3 0.0078 15.7 0.3 1.2 1 0 0 1 1 1 1 Transposase DDE domain Corona_nucleoca PF00937.16 001195547.1_39722001_2 - 0.0077 15.2 6.9 0.01 14.8 6.9 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein TP2 PF01254.16 001195547.1_39722001_2 - 5 7.6 18.1 8.1 6.9 18.1 1.3 1 0 0 1 1 1 0 Nuclear transition protein 2 STAG PF08514.9 001195547.1_39722001_3 - 0.93 9.3 3.4 1.7 8.4 3.4 1.5 1 1 0 1 1 1 0 STAG domain GSHPx PF00255.17 001145837.1_39723001_1 - 5.3e-38 128.8 0.0 7.9e-38 128.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 001145837.1_39723001_1 - 8.6e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.12 001145837.1_39723001_1 - 0.058 13.1 0.0 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 SCO1/SenC Acyl-CoA_dh_C PF12806.5 001145837.1_39723001_1 - 0.12 12.3 1.4 0.21 11.6 1.4 1.3 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like DUF1279 PF06916.11 001280234.1_39724001_2 - 7.8e-22 77.5 0.2 1.3e-21 76.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Apolipoprotein PF01442.16 001280234.1_39724001_2 - 0.017 14.9 0.9 0.026 14.3 0.9 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DctP PF03480.11 001280234.1_39724001_2 - 0.059 12.6 0.1 0.082 12.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 LEA_4 PF02987.14 001280234.1_39724001_2 - 0.22 11.5 3.1 0.37 10.8 3.1 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein TPR_2 PF07719.15 001280342.1_39725001_1 - 1.1e-06 28.1 5.2 0.071 13.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.26 001280342.1_39725001_1 - 4.8e-06 26.0 7.6 0.024 14.3 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.4 001280342.1_39725001_1 - 0.052 14.1 0.1 0.4 11.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.4 001280342.1_39725001_1 - 0.087 13.0 0.2 6.8 6.9 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.4 001280342.1_39725001_1 - 0.39 10.9 3.3 30 5.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.5 001280342.1_39725001_1 - 0.92 9.6 5.2 2.3 8.3 4.4 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Tubulin PF00091.23 001246378.1_39724001_3 - 9.7e-69 231.4 0.0 1.5e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001246378.1_39724001_3 - 9.6e-43 145.3 0.1 1.5e-42 144.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001246378.1_39724001_3 - 1.4e-05 25.2 0.0 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001246378.1_39724001_3 - 0.0081 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.4 001246378.1_39724001_3 - 0.018 14.1 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin like G_glu_transpept PF01019.19 001280452.1_39725001_2 - 4.5e-151 504.0 0.0 1.3e-126 423.3 0.0 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase Nitro_FeMo-Co PF02579.15 001280452.1_39725001_2 - 0.15 12.3 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Cupin_8 PF13621.4 001280177.1_39724001_3 - 2.4e-33 115.9 0.3 4e-33 115.1 0.3 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.10 001280177.1_39724001_3 - 0.00035 20.0 0.0 0.63 9.3 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Rcd1 PF04078.11 001246448.1_39725001_1 - 1.6e-135 450.3 0.9 1.9e-135 450.0 0.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like ELM2 PF01448.22 001280521.1_39725001_2 - 1.9e-08 34.8 0.1 4.6e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.29 001280521.1_39725001_2 - 4.9e-06 26.5 0.1 1.3e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.3 001280521.1_39725001_2 - 0.0055 16.4 0.3 0.013 15.3 0.3 1.6 1 0 0 1 1 1 1 Myb DNA-binding like GAT PF03127.12 001280521.1_39725001_2 - 0.031 14.4 0.1 0.1 12.8 0.1 1.8 1 0 0 1 1 1 0 GAT domain PKI PF02827.14 001280521.1_39725001_2 - 0.34 11.0 2.1 0.81 9.8 2.1 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor BTB PF00651.29 001280025.1_39724001_2 - 0.0035 17.4 0.1 0.037 14.1 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain OTCace_N PF02729.19 001280025.1_39724001_2 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DEAD PF00270.27 001280265.1_39725001_3 - 7.6e-49 165.7 0.0 1.4e-48 164.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001280265.1_39725001_3 - 3.5e-30 104.5 0.0 7.4e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001280265.1_39725001_3 - 0.00011 22.2 0.0 0.00026 20.9 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ferritin PF00210.22 001280265.1_39725001_3 - 0.12 12.1 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Ferritin-like domain SAPS PF04499.13 001280495.1_39726001_2 - 2.8e-115 385.8 0.0 7.5e-70 235.9 0.3 2.1 1 1 1 2 2 2 2 SIT4 phosphatase-associated protein Ig_2 PF13895.4 001009045.1_39723001_1 - 1.6e-18 66.6 0.0 2.3e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001009045.1_39723001_1 - 3.7e-11 42.9 0.0 8.6e-08 32.1 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001009045.1_39723001_1 - 2e-10 41.0 0.1 0.00021 21.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain SIT PF15330.4 001009045.1_39723001_1 - 0.002 18.4 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT DUF4808 PF16066.3 001009045.1_39723001_1 - 0.11 13.0 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) CEP19 PF14933.4 001251931.1_39725001_1 - 0.21 11.7 0.0 0.35 11.0 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein Fer4_2 PF12797.5 001251931.1_39725001_3 - 1.4 9.0 14.9 8.4 6.6 0.5 4.0 3 0 0 3 3 3 0 4Fe-4S binding domain Abhydrolase_1 PF00561.18 001280039.1_39725001_1 - 4.1e-28 98.6 0.0 5.3e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001280039.1_39725001_1 - 2.8e-08 33.2 0.0 9.3e-08 31.5 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.12 001280039.1_39725001_1 - 0.0026 16.4 0.0 0.0039 15.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.9 001280039.1_39725001_1 - 0.0031 16.8 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Humanin PF15040.4 001193642.1_39724001_1 - 1e-14 53.6 1.3 2e-14 52.6 1.3 1.6 1 0 0 1 1 1 1 Humanin family zf-CCHC PF00098.21 001280422.1_39724001_1 - 1.1e-06 28.3 30.3 0.0002 21.1 0.4 4.5 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.4 001280422.1_39724001_1 - 0.00042 20.1 27.1 0.31 10.9 0.2 4.9 3 2 2 5 5 5 4 Zinc knuckle DUF2318 PF10080.7 001280422.1_39724001_1 - 0.55 10.3 3.2 1.8 8.6 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) Fcf2 PF08698.9 001280405.1_39725001_3 - 1e-39 134.7 0.8 6.2e-39 132.2 0.8 2.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing TB2_DP1_HVA22 PF03134.17 001246540.1_39724001_3 - 2.8e-27 94.3 9.7 4.7e-27 93.6 9.7 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.7 001246540.1_39724001_3 - 0.09 12.9 2.9 0.14 12.2 2.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) ERCC4 PF02732.13 001280496.1_39726001_3 - 1.1e-25 90.5 0.0 1.8e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.4 001280496.1_39726001_3 - 0.013 15.7 0.0 0.039 14.2 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_12 PF13424.4 001280205.1_39724001_1 - 9.6e-09 35.3 11.7 0.064 13.4 0.3 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat zf-MYND PF01753.16 001280205.1_39724001_1 - 2.2e-08 33.9 7.3 4e-08 33.1 7.3 1.5 1 0 0 1 1 1 1 MYND finger TPR_8 PF13181.4 001280205.1_39724001_1 - 4.6e-06 26.3 9.4 0.46 10.7 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.15 001280205.1_39724001_1 - 5.8e-06 25.9 10.0 0.023 14.6 0.9 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.26 001280205.1_39724001_1 - 4.2e-05 23.0 11.4 0.21 11.4 0.5 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.4 001280205.1_39724001_1 - 0.023 14.9 2.8 1.3 9.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.4 001280205.1_39724001_1 - 0.19 11.5 3.7 14 5.6 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.4 001280205.1_39724001_1 - 0.89 10.0 3.4 15 6.1 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.4 001280205.1_39724001_1 - 2.2 8.9 5.8 81 4.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-Mss51 PF13824.4 001280205.1_39724001_1 - 3.1 7.9 5.8 5.3 7.1 4.8 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_16 PF13432.4 001280205.1_39724001_1 - 3.3 8.3 7.1 24 5.6 1.8 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat dsrm PF00035.24 001279769.1_39724001_2 - 1.1e-31 109.2 0.4 4.3e-13 49.6 0.0 3.6 3 0 0 3 3 3 3 Double-stranded RNA binding motif Staufen_C PF16482.3 001279769.1_39724001_2 - 2e-09 37.5 0.5 2.1e-07 30.9 0.0 3.1 2 1 1 3 3 3 1 Staufen C-terminal domain DND1_DSRM PF14709.5 001279769.1_39724001_2 - 2.6e-07 30.7 1.7 0.0061 16.7 0.2 3.9 3 1 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 APO_RNA-bind PF05634.9 001279769.1_39724001_2 - 0.00088 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 APO RNA-binding NTR PF01759.19 001242624.1_39723001_1 - 0.063 13.0 0.0 0.24 11.1 0.0 1.9 1 1 0 1 1 1 0 UNC-6/NTR/C345C module DUF1777 PF08648.10 001279989.1_39724001_1 - 1.8 8.7 22.6 2.5 8.2 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Hexapep PF00132.22 001279989.1_39724001_2 - 0.00069 19.1 1.3 0.0012 18.3 1.3 1.4 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) DEAD PF00270.27 001279989.1_39724001_3 - 2.2e-43 147.9 0.2 3.6e-43 147.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001279989.1_39724001_3 - 2.5e-30 105.0 0.0 8.9e-30 103.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.4 001279989.1_39724001_3 - 0.0034 17.6 2.9 0.0049 17.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain BBIP10 PF14777.4 001280347.1_39725001_3 - 2.2e-29 100.7 4.5 2.2e-29 100.7 4.5 1.6 2 0 0 2 2 2 1 Cilia BBSome complex subunit 10 Arfaptin PF06456.11 001280533.1_39724001_1 - 1.1e-84 283.5 1.9 1.7e-84 282.8 1.9 1.3 1 0 0 1 1 1 1 Arfaptin-like domain PDZ PF00595.22 001280533.1_39724001_1 - 3.8e-10 39.8 0.2 6.5e-10 39.1 0.2 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) BAR PF03114.16 001280533.1_39724001_1 - 1.4e-05 24.8 1.6 0.00011 21.8 1.6 2.0 1 1 0 1 1 1 1 BAR domain PDZ_2 PF13180.4 001280533.1_39724001_1 - 5.3e-05 23.3 0.1 0.00019 21.6 0.0 1.9 2 0 0 2 2 2 1 PDZ domain BAR_3 PF16746.3 001280533.1_39724001_1 - 0.00036 20.1 1.5 0.45 10.0 0.4 2.2 2 0 0 2 2 2 2 BAR domain of APPL family DALR_1 PF05746.13 001280533.1_39724001_1 - 0.026 14.6 0.1 0.28 11.3 0.1 2.2 2 0 0 2 2 2 0 DALR anticodon binding domain Ig_2 PF13895.4 001008980.1_39725001_1 - 1.1e-30 105.6 3.0 5.8e-15 55.3 0.1 4.3 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.4 001008980.1_39725001_1 - 3.1e-25 88.4 2.4 8.2e-06 26.2 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.23 001008980.1_39725001_1 - 2.4e-14 53.1 0.6 0.00032 20.7 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.15 001008980.1_39725001_1 - 0.00016 21.6 5.3 6.5 6.8 0.0 6.0 5 2 1 6 6 6 1 Immunoglobulin V-set domain EphA2_TM PF14575.4 001008980.1_39725001_1 - 0.091 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HemY_N PF07219.11 001008980.1_39725001_1 - 0.14 12.2 1.5 0.28 11.2 1.5 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Amnionless PF14828.4 001008980.1_39725001_1 - 0.16 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless SIT PF15330.4 001008980.1_39725001_1 - 3 8.1 6.3 1.2e+02 3.0 6.2 2.6 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT IMUP PF15761.3 001008980.1_39725001_2 - 4.3 7.9 8.5 9.5 6.8 8.5 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein zf-met PF12874.5 001302426.1_39724001_3 - 3.8e-35 119.2 28.9 6.1e-08 32.7 2.6 5.5 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.6 001302426.1_39724001_3 - 1.3e-25 88.9 28.6 1.9e-06 27.9 3.3 5.5 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.5 001302426.1_39724001_3 - 2e-08 34.4 22.5 0.022 14.9 0.2 5.2 5 0 0 5 5 5 5 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.10 001302426.1_39724001_3 - 3.9e-07 29.6 15.4 0.095 12.4 0.0 5.3 5 0 0 5 5 5 2 U1 zinc finger AKAP95 PF04988.10 001302426.1_39724001_3 - 1.9e-05 24.8 26.9 0.24 11.5 0.6 5.7 6 0 0 6 6 5 5 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_9 PF16293.3 001302426.1_39724001_3 - 0.0017 18.1 11.5 6.7 6.5 0.3 5.3 5 0 0 5 5 5 1 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.4 001302426.1_39724001_3 - 0.048 14.4 9.6 2 9.3 0.6 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger UPF0728 PF15092.4 001302426.1_39724001_3 - 0.11 12.2 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 zf-piccolo PF05715.11 001302426.1_39724001_3 - 0.17 12.0 13.5 18 5.5 0.2 5.3 5 0 0 5 5 5 0 Piccolo Zn-finger zf-C2H2 PF00096.24 001302426.1_39724001_3 - 0.21 12.0 18.0 3.2 8.3 2.0 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type GATA PF00320.25 001302426.1_39724001_3 - 0.7 9.4 5.2 20 4.8 0.1 3.6 3 0 0 3 3 3 0 GATA zinc finger zf-RING_7 PF02591.13 001302426.1_39724001_3 - 1.5 8.9 8.3 34 4.6 0.1 4.5 5 0 0 5 5 5 0 C4-type zinc ribbon domain G-alpha PF00503.18 001280137.1_39724001_1 - 1.3e-124 415.8 1.2 1.5e-124 415.6 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.19 001280137.1_39724001_1 - 5.4e-17 61.7 0.1 2.2e-12 46.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001280137.1_39724001_1 - 5.6e-05 22.5 0.8 0.074 12.3 0.6 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.11 001280137.1_39724001_1 - 0.00059 19.9 0.1 1.6 8.9 0.1 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DUF261 PF03196.11 001280137.1_39724001_1 - 0.11 12.5 0.4 5.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF261 AAA_16 PF13191.4 001280137.1_39724001_1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.20 001280137.1_39724001_1 - 0.2 11.1 0.9 10 5.6 0.6 2.3 2 0 0 2 2 2 0 Ras family NAD_binding_5 PF07994.10 001280365.1_39724001_2 - 1.3e-138 461.7 0.0 1.6e-138 461.4 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.15 001280365.1_39724001_2 - 8.4e-46 154.6 0.0 8.4e-46 154.6 0.0 2.0 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase TSGP1 PF07771.9 001280365.1_39724001_2 - 0.45 10.5 7.5 0.71 9.9 7.5 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 RAC_head PF16717.3 001280417.1_39725001_1 - 1.9e-21 76.7 11.3 1.9e-21 76.7 11.3 4.6 5 1 0 5 5 5 1 Ribosome-associated complex head domain Myb_DNA-binding PF00249.29 001280417.1_39725001_1 - 2.4e-21 75.5 3.9 9.6e-12 44.7 0.2 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain DnaJ PF00226.29 001280417.1_39725001_1 - 7.7e-15 54.6 0.2 7.7e-15 54.6 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.4 001280417.1_39725001_1 - 9.5e-12 44.8 0.8 1.1e-06 28.6 0.2 3.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SR-25 PF10500.7 001280237.1_39723001_2 - 0.53 9.7 12.0 0.74 9.2 12.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.23 001280237.1_39723001_3 - 2.9e-68 230.0 0.0 4.4e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280237.1_39723001_3 - 4e-42 144.2 0.0 5.4e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001280237.1_39723001_3 - 0.00033 20.0 0.0 0.001 18.3 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.12 001280237.1_39723001_3 - 0.016 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Humanin PF15040.4 001193643.1_39724001_1 - 8.9e-15 53.8 1.8 1.7e-14 52.8 1.8 1.5 1 0 0 1 1 1 1 Humanin family Tyr-DNA_phospho PF06087.10 001246628.1_39725001_3 - 7.8e-140 466.4 0.0 9.8e-140 466.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase RMMBL PF07521.10 001246628.1_39725001_3 - 0.13 12.1 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain OPA3 PF07047.10 001242408.1_39722001_2 - 1.7e-42 144.0 0.1 2.5e-42 143.4 0.1 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2730 PF10805.6 001242408.1_39722001_2 - 0.07 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) BRO1 PF03097.16 001246393.1_39725001_2 - 6.2e-42 143.6 0.3 8.5e-42 143.2 0.3 1.1 1 0 0 1 1 1 1 BRO1-like domain Cpn60_TCP1 PF00118.22 001246626.1_39724001_3 - 3.2e-147 491.0 11.7 3.8e-147 490.7 11.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2529 PF10740.7 001246626.1_39724001_3 - 0.005 16.3 0.3 0.017 14.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2529) Ribosomal_S13 PF00416.20 001246626.1_39724001_3 - 0.17 12.2 0.9 0.63 10.3 0.3 2.2 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Crystall PF00030.17 001135665.1_39722001_1 - 2.1e-61 203.9 2.9 4.2e-31 106.8 0.2 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001135665.1_39722001_1 - 1.8e-07 30.9 0.1 0.0019 18.0 0.1 2.4 2 0 0 2 2 2 2 Peptidase inhibitor family I36 LRR_9 PF14580.4 001279933.1_39724001_2 - 5.6e-14 51.9 1.4 1.3e-13 50.7 1.4 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.5 001279933.1_39724001_2 - 3.4e-10 39.8 8.4 0.00025 21.2 1.8 3.5 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001279933.1_39724001_2 - 1e-05 25.1 9.5 2.2e-05 24.0 4.9 3.0 1 1 2 3 3 3 3 Leucine rich repeat MerR_2 PF13591.4 001279933.1_39724001_2 - 0.024 14.3 1.1 3.7 7.3 0.1 2.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein LRR_6 PF13516.4 001279933.1_39724001_2 - 0.34 10.9 4.6 11 6.3 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Sacchrp_dh_NADP PF03435.16 001246632.1_39724001_2 - 9.9e-28 96.9 0.0 1.4e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TRM PF02005.14 001280156.1_39725001_3 - 7.9e-151 502.4 0.0 9.2e-151 502.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase zf-CCCH PF00642.22 001280156.1_39725001_3 - 4.5e-07 29.5 5.9 9.8e-07 28.4 5.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Met_10 PF02475.14 001280156.1_39725001_3 - 3e-06 27.0 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Torus PF16131.3 001280156.1_39725001_3 - 0.00045 20.7 0.4 0.00094 19.7 0.4 1.5 1 0 0 1 1 1 1 Torus domain Cons_hypoth95 PF03602.13 001280156.1_39725001_3 - 0.0025 17.3 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Aldedh PF00171.20 001280017.1_39724001_3 - 1.8e-185 616.8 0.0 2.1e-185 616.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family XK-related PF09815.7 001195134.1_39724001_3 - 8.6e-69 232.0 25.9 1e-68 231.7 25.9 1.1 1 0 0 1 1 1 1 XK-related protein UPAR_LY6 PF00021.19 001280183.1_39724001_2 - 1.4e-20 73.6 3.9 9.7e-20 70.9 0.6 2.4 2 0 0 2 2 2 2 u-PAR/Ly-6 domain zf-H2C2_2 PF13465.4 001114622.2_39729001_2 - 3.4e-46 153.5 83.2 3.4e-08 33.4 1.1 12.5 13 0 0 13 13 12 9 Zinc-finger double domain zf-C2H2 PF00096.24 001114622.2_39729001_2 - 1e-30 104.3 92.0 0.0002 21.5 0.2 11.3 11 0 0 11 11 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001114622.2_39729001_2 - 5.8e-23 79.4 99.8 0.00069 20.1 1.1 12.1 12 1 1 13 13 10 10 C2H2-type zinc finger BTB PF00651.29 001114622.2_39729001_2 - 1.5e-22 79.7 2.1 2.5e-22 79.1 2.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.4 001114622.2_39729001_2 - 1.1e-07 31.4 71.9 0.00079 19.2 0.9 10.3 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2_11 PF16622.3 001114622.2_39729001_2 - 1.4e-06 27.8 60.8 0.034 13.8 0.2 10.9 11 0 0 11 11 11 4 zinc-finger C2H2-type zf-met PF12874.5 001114622.2_39729001_2 - 9.9e-06 25.6 70.4 0.088 13.1 0.4 10.6 11 0 0 11 11 10 5 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.3 001114622.2_39729001_2 - 0.0067 16.6 4.4 0.0067 16.6 4.4 5.2 1 1 4 5 5 5 1 C2H2-type zinc ribbon BolA PF01722.16 001114622.2_39729001_2 - 0.0083 16.3 17.5 0.047 13.8 1.3 5.3 3 1 1 4 4 4 1 BolA-like protein zf-C2H2_jaz PF12171.6 001114622.2_39729001_2 - 0.012 15.8 49.4 0.91 9.8 0.4 9.9 11 0 0 11 11 10 0 Zinc-finger double-stranded RNA-binding HypA PF01155.17 001114622.2_39729001_2 - 0.28 11.1 31.4 0.61 10.0 2.5 5.2 1 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.12 001114622.2_39729001_2 - 0.71 9.8 21.8 1.4 8.8 0.3 6.1 4 2 1 5 5 5 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.3 001114622.2_39729001_2 - 1.5 9.5 32.4 15 6.3 2.6 5.9 3 1 3 6 6 6 0 zinc-ribbon family Zn-ribbon_8 PF09723.8 001114622.2_39729001_2 - 3.9 7.6 44.4 0.62 10.1 1.8 7.5 4 3 4 8 8 8 0 Zinc ribbon domain CLAMP PF14769.4 001246401.1_39724001_1 - 1.1e-33 115.5 0.4 1.9e-33 114.7 0.4 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 DUF1690 PF07956.9 001246401.1_39724001_1 - 1 9.6 4.5 1.4 9.2 0.8 2.4 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF883 PF05957.11 001246401.1_39724001_1 - 9.7 6.7 7.1 16 6.0 2.7 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-RanBP PF00641.16 001280490.1_39725001_1 - 7.2e-13 47.5 7.4 1.1e-12 46.9 7.4 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.20 001280490.1_39725001_1 - 2.4e-10 40.0 0.0 9.8e-10 38.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coatomer_WDAD PF04053.12 001280386.1_39727001_3 - 5.7e-169 562.7 0.0 9e-169 562.1 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.30 001280386.1_39727001_3 - 5.1e-40 134.6 7.5 1.3e-08 35.2 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280386.1_39727001_3 - 2.5e-06 27.5 0.9 5.1 7.3 0.0 6.3 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain MetallophosC PF16370.3 001280386.1_39727001_3 - 0.059 13.5 0.0 0.6 10.2 0.0 2.3 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Annexin PF00191.18 001246394.1_39724001_3 - 4e-100 327.8 6.9 2.3e-26 91.5 0.4 4.2 4 0 0 4 4 4 4 Annexin ANF_receptor PF01094.26 001164702.1_39726001_1 - 1.9e-77 260.6 0.0 2.6e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001164702.1_39726001_1 - 7.8e-54 181.4 0.1 1.5e-53 180.5 0.1 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001164702.1_39726001_1 - 2.2e-46 156.6 0.0 5.9e-46 155.2 0.0 1.8 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001164702.1_39726001_1 - 2.9e-18 66.0 0.0 5.7e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.4 001164702.1_39726001_1 - 4.9e-08 32.9 0.0 8.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein FAST_1 PF06743.13 001280190.1_39725001_1 - 1.9e-21 75.6 2.0 1.9e-21 75.6 2.0 2.6 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 RAP PF08373.8 001280190.1_39725001_1 - 4.9e-12 45.6 0.0 1.3e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 RAP domain FAST_2 PF08368.10 001280190.1_39725001_1 - 6.4e-09 36.4 0.6 3.8e-08 33.9 0.1 2.6 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 2 zf-C3HC4_3 PF13920.4 001280304.1_39725001_2 - 6.1e-10 38.7 7.8 6.1e-10 38.7 7.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001280304.1_39725001_2 - 1.1e-08 35.1 11.2 1.1e-08 35.1 11.2 2.2 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.4 001280304.1_39725001_2 - 7.6e-08 31.9 15.8 1e-07 31.5 11.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001280304.1_39725001_2 - 9.2e-08 31.7 9.0 9.2e-08 31.7 9.0 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.4 001280304.1_39725001_2 - 9.2e-07 28.7 7.6 9.2e-07 28.7 7.6 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.23 001280304.1_39725001_2 - 1e-06 28.4 11.9 1e-06 28.4 11.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001280304.1_39725001_2 - 1.2e-06 28.3 9.7 1.2e-06 28.3 9.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.5 001280304.1_39725001_2 - 8.4e-06 25.8 10.0 8.4e-06 25.8 10.0 2.4 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.4 001280304.1_39725001_2 - 0.0016 18.4 11.2 0.0016 18.4 11.2 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.4 001280304.1_39725001_2 - 0.0071 16.1 3.0 0.016 14.9 3.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.3 001280304.1_39725001_2 - 0.38 10.3 12.3 0.022 14.3 6.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.5 001280304.1_39725001_2 - 4.4 7.3 12.1 4.8 7.2 8.0 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger MFS_2 PF13347.4 001280162.1_39725001_3 - 2.5e-124 414.9 25.3 3e-124 414.7 25.3 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein DUF1201 PF06716.9 001280162.1_39725001_3 - 0.16 11.8 0.1 0.16 11.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) SpoIIE PF07228.10 001246519.1_39724001_3 - 3.4e-14 53.1 0.0 5.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.4 001246519.1_39724001_3 - 2.1e-05 24.2 0.7 0.00018 21.1 0.7 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.19 001246519.1_39724001_3 - 0.00021 20.9 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C MARVEL PF01284.21 001246505.1_39724001_1 - 9.3e-11 41.8 11.8 1.7e-10 40.9 11.8 1.4 1 0 0 1 1 1 1 Membrane-associating domain AAA PF00004.27 001279896.1_39724001_3 - 1.3e-39 135.5 0.0 4.7e-39 133.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 001279896.1_39724001_3 - 0.00043 20.4 0.0 0.0084 16.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.12 001279896.1_39724001_3 - 0.0013 18.6 0.0 0.005 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001279896.1_39724001_3 - 0.0033 17.7 0.1 0.044 14.0 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.11 001279896.1_39724001_3 - 0.0075 15.3 0.0 0.02 13.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.12 001279896.1_39724001_3 - 0.0086 16.1 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.4 001279896.1_39724001_3 - 0.013 15.5 0.2 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.10 001279896.1_39724001_3 - 0.023 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.4 001279896.1_39724001_3 - 0.023 15.1 0.0 0.059 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.4 001279896.1_39724001_3 - 0.039 14.1 0.0 0.039 14.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.15 001279896.1_39724001_3 - 0.079 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.19 001279896.1_39724001_3 - 0.093 12.0 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.4 001279896.1_39724001_3 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.11 001279896.1_39724001_3 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Ig_3 PF13927.4 001251858.1_39724001_2 - 0.0005 20.5 0.1 0.0017 18.8 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.23 001251858.1_39724001_2 - 0.017 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.4 001251858.1_39724001_2 - 0.058 13.6 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain V-set PF07686.15 001251858.1_39724001_2 - 0.086 12.9 1.3 23 5.1 0.0 3.1 1 1 2 3 3 3 0 Immunoglobulin V-set domain EpoR_lig-bind PF09067.8 001251858.1_39724001_2 - 0.088 12.9 0.0 0.22 11.6 0.0 1.5 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding Kelch_6 PF13964.4 001280286.1_39724001_1 - 2.3e-24 84.7 5.8 9.4e-09 35.1 0.1 5.5 4 1 1 5 5 5 3 Kelch motif BTB PF00651.29 001280286.1_39724001_1 - 3.3e-23 81.9 0.1 1.5e-22 79.8 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.23 001280286.1_39724001_1 - 6.1e-23 80.0 2.0 4.1e-07 29.3 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.4 001280286.1_39724001_1 - 3e-18 65.4 3.1 6.9e-07 29.0 0.1 4.9 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.4 001280286.1_39724001_1 - 1.2e-12 47.6 1.3 2.3e-06 27.6 0.1 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.13 001280286.1_39724001_1 - 1.5e-11 43.6 2.6 0.00096 18.9 0.1 4.1 3 1 0 3 3 3 3 Kelch motif BACK PF07707.13 001280286.1_39724001_1 - 1.5e-10 40.9 0.9 4.1e-10 39.5 0.0 2.2 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_5 PF13854.4 001280286.1_39724001_1 - 0.0016 18.3 5.0 2.3 8.2 0.5 3.9 4 0 0 4 4 4 2 Kelch motif zf-C2H2 PF00096.24 001280370.1_39724001_2 - 6.7e-13 48.2 25.5 0.00029 21.0 0.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001280370.1_39724001_2 - 8.5e-09 35.4 30.7 1.4e-05 25.2 2.1 5.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.4 001280370.1_39724001_2 - 0.00012 22.4 33.1 0.0012 19.3 3.4 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001280370.1_39724001_2 - 0.00014 21.5 1.6 0.00014 21.5 1.6 3.4 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001280370.1_39724001_2 - 0.029 14.5 6.9 0.14 12.3 6.8 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.4 001280370.1_39724001_2 - 0.9 9.2 23.2 0.11 12.2 1.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain MHC2-interact PF09307.8 001144836.1_39723001_3 - 1.8e-39 134.0 1.7 3e-39 133.3 1.7 1.4 1 0 0 1 1 1 1 CLIP, MHC2 interacting MHCassoc_trimer PF08831.8 001144836.1_39723001_3 - 7.8e-34 115.4 4.5 1.3e-33 114.6 4.5 1.4 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain ECH_1 PF00378.18 001098573.1_39725001_1 - 6.5e-34 117.2 0.0 9.1e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.3 001098573.1_39725001_1 - 5e-17 62.3 0.0 7.3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Alg6_Alg8 PF03155.13 001280231.1_39724001_3 - 1.4e-171 571.5 31.5 1.6e-171 571.3 31.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Abhydrolase_2 PF02230.14 001246375.1_39724001_2 - 4.6e-41 140.9 0.1 6e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.16 001246375.1_39724001_2 - 1.7e-06 27.7 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.11 001246375.1_39724001_2 - 2.6e-06 27.3 0.0 0.0009 19.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001246375.1_39724001_2 - 3.6e-06 26.3 0.8 0.0017 17.6 0.1 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.5 001246375.1_39724001_2 - 1.5e-05 24.6 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.18 001246375.1_39724001_2 - 3.7e-05 23.4 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.19 001246375.1_39724001_2 - 0.0014 18.0 0.5 0.22 10.8 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.18 001246375.1_39724001_2 - 0.0019 17.8 0.5 0.0088 15.6 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.11 001246375.1_39724001_2 - 0.003 17.1 0.0 0.0086 15.6 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.5 001246375.1_39724001_2 - 0.0063 17.0 0.0 0.0095 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.18 001246375.1_39724001_2 - 0.043 13.8 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.23 001246375.1_39724001_2 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) 4F5 PF04419.12 001251924.1_39722001_2 - 1.1e-10 42.1 10.8 1.1e-10 42.1 10.8 2.3 3 0 0 3 3 3 1 4F5 protein family BCDHK_Adom3 PF10436.7 001246531.1_39724001_3 - 8.7e-51 171.8 0.2 1.2e-50 171.3 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.24 001246531.1_39724001_3 - 2.1e-14 53.9 0.0 3.9e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Slu7 PF11708.6 001329720.1_39725001_2 - 1.9e-108 362.2 14.7 1.9e-108 362.2 14.7 2.5 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.4 001329720.1_39725001_2 - 0.077 12.6 0.6 0.16 11.5 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3492 PF11997.6 001329720.1_39725001_2 - 0.97 9.0 5.6 1.8 8.1 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) ATP-synt_S1 PF05827.10 001280373.1_39725001_1 - 3.8e-52 175.9 0.5 5.4e-52 175.4 0.5 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.15 001280373.1_39725001_1 - 0.062 12.7 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) HGTP_anticodon PF03129.18 001280478.1_39725001_3 - 1.2e-23 82.9 0.0 1.2e-22 79.7 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.18 001280478.1_39725001_3 - 9.8e-11 41.5 6.5 2.8e-10 40.1 6.5 1.8 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.23 001280478.1_39725001_3 - 7.5e-10 38.9 0.0 1.9e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3699 PF12480.6 001246439.1_39725001_2 - 1.1e-26 92.6 0.2 1.7e-26 92.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3699) TPH PF13868.4 001280103.1_39724001_3 - 3.3e-14 52.1 135.1 3.3e-14 52.1 135.1 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Ku_N PF03731.13 001280505.1_39725001_1 - 8.3e-79 264.2 1.4 1.9e-78 263.1 1.6 1.5 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.14 001280505.1_39725001_1 - 2.6e-49 167.6 0.1 4.6e-49 166.7 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.12 001280505.1_39725001_1 - 1.7e-28 99.0 0.1 6.5e-28 97.1 0.1 2.1 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.25 001280505.1_39725001_1 - 1.7e-09 37.0 0.1 3.7e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 SAP domain SAP30_Sin3_bdg PF13867.4 001280505.1_39725001_1 - 0.014 15.5 0.0 0.08 13.1 0.0 2.2 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 ocr PF08684.8 001280505.1_39725001_1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 DNA mimic ocr RIIa PF02197.15 001246579.1_39725001_1 - 4.4e-15 54.9 0.0 8.7e-15 54.0 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit TPH PF13868.4 001302431.1_39724001_2 - 5.9e-83 278.2 162.0 5.9e-83 278.2 162.0 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Sec1 PF00995.21 001280150.1_39724001_1 - 4.3e-126 422.3 0.0 4.9e-126 422.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DASH_Hsk3 PF08227.9 001280150.1_39724001_1 - 0.029 14.6 1.1 0.65 10.3 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Ig_2 PF13895.4 001170592.1_39723001_3 - 8.6e-10 38.7 0.0 0.00079 19.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001170592.1_39723001_3 - 6.8e-08 32.9 0.0 0.00019 21.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001170592.1_39723001_3 - 9.2e-05 22.4 0.0 0.0025 17.8 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Serglycin PF04360.10 001280468.1_39726001_1 - 0.036 13.9 4.2 0.067 13.0 4.2 1.4 1 0 0 1 1 1 0 Serglycin AAA PF00004.27 001246524.1_39724001_2 - 1e-42 145.5 0.0 2.1e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.12 001246524.1_39724001_2 - 4.4e-07 30.1 0.0 9.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.12 001246524.1_39724001_2 - 5.9e-06 26.2 0.0 2.6e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.4 001246524.1_39724001_2 - 8.5e-06 26.1 0.1 0.00011 22.5 0.0 2.5 2 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.4 001246524.1_39724001_2 - 7.8e-05 22.8 1.7 0.016 15.4 0.0 2.9 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.10 001246524.1_39724001_2 - 0.00016 20.9 0.0 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.15 001246524.1_39724001_2 - 0.0024 17.6 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.11 001246524.1_39724001_2 - 0.0025 16.7 0.0 0.0047 15.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.4 001246524.1_39724001_2 - 0.0028 17.7 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001246524.1_39724001_2 - 0.0052 17.2 0.2 0.03 14.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.19 001246524.1_39724001_2 - 0.01 15.1 0.1 0.023 13.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.9 001246524.1_39724001_2 - 0.01 15.5 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.11 001246524.1_39724001_2 - 0.015 14.5 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 KaiC PhoH PF02562.14 001246524.1_39724001_2 - 0.016 14.6 0.0 0.19 11.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.4 001246524.1_39724001_2 - 0.03 14.4 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RILP PF11461.6 001246524.1_39724001_2 - 0.035 14.2 3.4 0.075 13.1 3.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.24 001246524.1_39724001_2 - 0.042 13.4 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.4 001246524.1_39724001_2 - 0.046 13.3 0.0 0.098 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.15 001246524.1_39724001_2 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.15 001246524.1_39724001_2 - 0.068 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.4 001246524.1_39724001_2 - 0.082 12.3 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.4 001246524.1_39724001_2 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.20 001246524.1_39724001_2 - 0.098 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.4 001246524.1_39724001_2 - 0.16 11.6 0.7 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.10 001246524.1_39724001_2 - 0.72 9.7 4.0 1.9 8.4 0.9 2.6 3 0 0 3 3 3 0 Laminin Domain II Prolamin_like PF05617.9 001246524.1_39724001_3 - 0.015 15.3 1.1 0.027 14.5 0.1 2.0 2 0 0 2 2 2 0 Prolamin-like Speriolin_N PF15058.4 001280378.1_39724001_3 - 1.8e-77 259.8 18.4 1.8e-77 259.8 18.4 4.1 2 2 0 3 3 3 1 Speriolin N terminus Speriolin_C PF15059.4 001280378.1_39724001_3 - 8.8e-61 204.3 0.0 1.3e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Speriolin C-terminus NEMO PF11577.6 001280378.1_39724001_3 - 0.023 14.6 2.6 0.16 11.9 1.4 2.2 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO ZapB PF06005.10 001280378.1_39724001_3 - 0.039 14.3 0.6 0.082 13.2 0.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.16 001280378.1_39724001_3 - 0.05 13.7 0.5 0.13 12.3 0.4 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper p450 PF00067.20 001280333.1_39724001_3 - 3.9e-74 249.9 0.0 4.9e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.20 001205233.1_39729001_1 - 1.4e-08 34.3 0.0 0.002 17.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.30 001280472.1_39725001_2 - 3.2e-11 43.4 16.6 0.001 19.7 0.2 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280472.1_39725001_2 - 0.0013 18.9 0.0 0.24 11.6 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.6 001280472.1_39725001_2 - 0.03 12.8 0.5 0.91 7.9 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 GBP PF02263.17 001280436.1_39725001_2 - 1.6e-96 322.5 0.1 2.5e-96 321.8 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.12 001280436.1_39725001_2 - 3.3e-07 29.9 0.3 5.3e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Septin PF00735.16 001280436.1_39725001_2 - 0.11 11.6 0.0 0.25 10.4 0.0 1.6 1 0 0 1 1 1 0 Septin Sod_Cu PF00080.18 001173530.1_39722001_1 - 2.8e-40 137.6 0.1 4.2e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.24 001173530.1_39722001_1 - 7.6e-10 39.0 0.1 1.2e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.13 001173530.1_39722001_1 - 0.29 11.4 1.9 6.4 7.1 0.0 3.2 3 0 0 3 3 3 0 BFD-like [2Fe-2S] binding domain Whi5 PF08528.9 001280476.1_39724001_2 - 0.96 9.0 8.1 4.1 7.0 0.7 2.5 2 0 0 2 2 2 0 Whi5 like LRR_8 PF13855.4 001302410.1_39726001_2 - 2.5e-26 91.1 8.1 2.1e-13 49.7 0.1 2.7 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.5 001302410.1_39726001_2 - 1.2e-11 44.4 8.7 6.1e-05 23.2 3.4 3.7 1 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.4 001302410.1_39726001_2 - 3.3e-05 23.3 0.4 0.0014 18.1 0.7 2.1 1 1 1 2 2 2 2 Leucine-rich repeat Ig_3 PF13927.4 001302410.1_39726001_2 - 8.5e-05 23.0 0.0 0.0012 19.3 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.14 001302410.1_39726001_2 - 9.2e-05 22.3 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.4 001302410.1_39726001_2 - 0.001 19.2 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain TPKR_C2 PF16920.3 001302410.1_39726001_2 - 0.01 15.8 0.5 0.025 14.6 0.5 1.7 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_1 PF00560.31 001302410.1_39726001_2 - 0.043 14.1 8.9 3 8.6 1.0 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRRCT PF01463.22 001302410.1_39726001_2 - 0.065 13.7 1.5 0.4 11.2 0.8 2.9 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain fn3 PF00041.19 001302410.1_39726001_2 - 0.079 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III domain FGGY_N PF00370.19 001328287.1_39724001_1 - 2.6e-84 282.5 0.0 3.5e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.14 001328287.1_39724001_1 - 8.8e-64 214.7 0.2 1.5e-63 214.0 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain KH_6 PF15985.3 001280437.1_39725001_1 - 2.5e-13 50.0 0.1 4.9e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 KH domain Rad21_Rec8_N PF04825.11 001280430.2_39725001_3 - 5.4e-24 84.4 0.0 9.2e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.14 001280430.2_39725001_3 - 2.6e-20 71.4 0.0 5.4e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.12 001280430.2_39725001_3 - 0.1 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA WD40 PF00400.30 001280453.1_39724001_2 - 8.4e-69 225.7 15.4 1.7e-09 38.0 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280453.1_39724001_2 - 1.5e-22 79.6 0.4 0.00059 20.0 0.0 7.1 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.3 001280453.1_39724001_2 - 4.4e-12 45.8 1.7 0.24 10.5 0.0 6.1 1 1 3 5 5 5 4 WD40-like domain Nup160 PF11715.6 001280453.1_39724001_2 - 3e-06 26.0 5.1 1.1 7.7 0.0 5.9 1 1 4 6 6 6 3 Nucleoporin Nup120/160 CEP19 PF14933.4 001280453.1_39724001_2 - 0.00042 20.5 0.1 0.00061 20.0 0.1 1.2 1 0 0 1 1 1 1 CEP19-like protein Ge1_WD40 PF16529.3 001280453.1_39724001_2 - 0.0012 17.8 4.7 0.44 9.3 0.4 3.7 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.6 001280453.1_39724001_2 - 0.013 13.7 0.0 0.49 8.5 0.0 3.0 2 1 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.4 001280453.1_39724001_2 - 0.029 14.7 0.6 1.6 9.2 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain Lectin_C PF00059.19 001079918.1_39722001_2 - 1.2e-17 64.4 1.3 1.2e-17 64.4 1.3 1.9 2 0 0 2 2 2 1 Lectin C-type domain Furin-like_2 PF15913.3 001079918.1_39722001_2 - 0.0081 16.2 0.3 0.017 15.1 0.3 1.5 1 0 0 1 1 1 1 Furin-like repeat, cysteine-rich F-box-like PF12937.5 001280348.1_39724001_1 - 3.8e-08 32.9 1.8 6.3e-08 32.2 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.31 001280348.1_39724001_1 - 5.4e-08 32.4 0.9 2e-07 30.6 0.2 2.3 2 0 0 2 2 2 1 F-box domain DUF4116 PF13475.4 001280348.1_39724001_1 - 0.014 15.0 0.4 0.038 13.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Aminotran_5 PF00266.17 001302528.1_39725001_1 - 5.5e-57 193.3 0.0 1.7e-55 188.4 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Hexapep PF00132.22 001246500.2_39724001_3 - 1.5e-09 37.1 17.0 6.7e-05 22.3 0.8 4.6 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.4 001246500.2_39724001_3 - 0.04 13.5 8.2 0.11 12.1 2.5 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Calcipressin PF04847.10 001098557.1_39725001_3 - 2.2e-60 203.5 0.3 2.9e-60 203.1 0.3 1.1 1 0 0 1 1 1 1 Calcipressin NuDC PF16273.3 001280350.1_39723001_3 - 1.9e-20 73.1 21.7 1.9e-20 73.1 21.7 3.9 4 1 0 4 4 4 1 Nuclear distribution C domain CS PF04969.14 001280350.1_39723001_3 - 8.9e-18 65.0 0.3 2.6e-17 63.5 0.1 1.9 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.4 001280350.1_39723001_3 - 3e-13 49.4 0.7 9.4e-13 47.8 0.7 1.9 1 1 0 1 1 1 1 N-terminal conserved domain of Nudc. DUF4604 PF15377.4 001280350.1_39723001_3 - 0.00051 20.4 8.9 0.00051 20.4 8.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) T2SSM PF04612.10 001280350.1_39723001_3 - 3.1 7.7 6.9 5.6 6.9 6.9 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M LRR_9 PF14580.4 001246364.1_39725001_2 - 2e-23 82.6 15.6 5.1e-14 52.0 2.8 3.6 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.5 001246364.1_39725001_2 - 1.4e-20 72.8 39.0 1.4e-07 31.5 5.7 5.9 3 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001246364.1_39725001_2 - 2.4e-16 59.1 66.9 1.6e-07 30.8 8.8 5.8 4 1 5 9 9 9 6 Leucine rich repeat DUF2322 PF10084.7 001246364.1_39725001_2 - 0.1 12.6 1.5 8.6 6.4 0.2 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) FHA PF00498.24 001280280.1_39725001_1 - 9.4e-14 51.4 0.0 2.1e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.4 001280280.1_39725001_1 - 6.3e-10 38.6 8.7 1.6e-09 37.3 8.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001280280.1_39725001_1 - 4.2e-09 36.0 11.5 4.2e-09 36.0 11.5 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.4 001280280.1_39725001_1 - 1.4e-08 34.3 8.9 1.4e-08 34.3 8.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001280280.1_39725001_1 - 9.2e-08 32.1 10.2 9.2e-08 32.1 10.2 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.4 001280280.1_39725001_1 - 7.6e-07 29.1 11.5 7.6e-07 29.1 11.5 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.4 001280280.1_39725001_1 - 1.2e-06 28.3 7.1 3.6e-06 26.7 7.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.4 001280280.1_39725001_1 - 3.4e-06 26.8 3.4 4.1e-06 26.6 1.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.4 001280280.1_39725001_1 - 5.9e-06 25.9 6.9 1.7e-05 24.4 6.9 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.5 001280280.1_39725001_1 - 7.2e-06 26.1 5.3 7.2e-06 26.1 5.3 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain Yop-YscD_cpl PF16697.3 001280280.1_39725001_1 - 0.00053 20.1 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_6 PF14835.4 001280280.1_39725001_1 - 0.006 16.3 4.6 0.014 15.1 4.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.5 001280280.1_39725001_1 - 0.017 15.0 2.3 0.017 15.0 2.3 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.3 001280280.1_39725001_1 - 0.024 14.7 6.9 0.051 13.6 6.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.4 001280280.1_39725001_1 - 0.042 13.4 4.6 0.13 11.9 4.6 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Golgin_A5 PF09787.7 001280280.1_39725001_1 - 0.087 12.1 28.6 0.16 11.3 28.6 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_30_3 PF08010.9 001280280.1_39725001_1 - 3.4 7.3 8.2 2 8.1 6.4 1.5 1 1 0 1 1 1 0 Bacteriophage protein GP30.3 DUF4665 PF15679.3 001280280.1_39725001_1 - 7.2 7.2 20.8 0.1 13.1 9.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) PLDc_N PF13396.4 001246615.1_39725001_1 - 0.3 10.9 5.9 0.68 9.8 5.9 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Peptidase_A22B PF04258.11 001246615.1_39725001_2 - 2.1e-93 312.8 9.4 2.8e-93 312.4 9.4 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Cpn60_TCP1 PF00118.22 001280305.1_39724001_2 - 1e-159 532.2 8.4 1.3e-159 531.9 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AIRS_C PF02769.20 001114731.1_39725001_3 - 1.5e-27 96.5 0.1 2.3e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.22 001114731.1_39725001_3 - 1.1e-09 38.7 0.1 2.4e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain V-set PF07686.15 001279873.1_39724001_3 - 6.6e-19 67.9 2.2 6.2e-12 45.5 0.2 3.4 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.4 001279873.1_39724001_3 - 2e-15 57.0 0.5 4.5e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.4 001279873.1_39724001_3 - 8.7e-14 51.5 0.3 1e-08 35.2 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001279873.1_39724001_3 - 1.9e-12 46.9 0.0 4.3e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.23 001279873.1_39724001_3 - 2.5e-11 43.4 0.2 2.7e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.3 001279873.1_39724001_3 - 0.0039 17.1 0.0 0.23 11.4 0.0 2.4 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.9 001279873.1_39724001_3 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Glyco_transf_29 PF00777.16 001193677.1_39723001_3 - 3e-28 98.8 0.0 4.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Glyco_transf_29 PF00777.16 001037291.1_39723001_1 - 7e-36 123.8 0.0 1.1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) RCC1 PF00415.16 001205205.1_39726001_2 - 8.1e-84 276.0 18.6 4e-14 52.8 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.4 001205205.1_39726001_2 - 2.8e-28 96.9 34.2 2.1e-08 33.6 0.4 7.7 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.12 001205205.1_39726001_2 - 0.022 14.5 0.0 7.8 6.3 0.0 3.2 3 0 0 3 3 3 0 Peptidase family C25, C terminal ig-like domain SUKH-3 PF14433.4 001205205.1_39726001_2 - 0.1 12.9 2.6 48 4.3 0.0 4.4 5 0 0 5 5 5 0 SUKH-3 immunity protein zf-H2C2_2 PF13465.4 001280353.1_39725001_3 - 3e-73 239.1 76.4 2.5e-09 37.1 0.8 12.7 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.24 001280353.1_39725001_3 - 2.9e-53 175.3 81.7 2e-06 27.8 0.6 12.1 12 0 0 12 12 12 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280353.1_39725001_3 - 9.5e-27 91.2 81.4 0.001 19.6 0.8 12.4 13 0 0 13 13 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001280353.1_39725001_3 - 5e-11 42.5 43.0 0.038 14.2 0.1 10.6 11 0 0 11 11 10 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001280353.1_39725001_3 - 3.4e-09 36.3 69.0 1.1e-05 25.1 0.4 11.1 12 0 0 12 12 12 7 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001280353.1_39725001_3 - 2e-08 34.1 45.8 0.0048 16.9 2.9 7.6 2 1 5 8 8 8 7 Zinc ribbon domain zinc_ribbon_15 PF17032.3 001280353.1_39725001_3 - 0.0015 19.1 37.7 0.49 11.0 2.2 6.8 3 1 4 7 7 7 4 zinc-ribbon family C1_4 PF07975.10 001280353.1_39725001_3 - 0.019 15.1 2.7 0.019 15.1 2.7 7.6 5 2 2 8 8 8 0 TFIIH C1-like domain LIM PF00412.20 001280353.1_39725001_3 - 0.036 14.2 45.8 0.15 12.2 1.9 7.5 4 1 4 8 8 8 0 LIM domain PknG_rubred PF16919.3 001280353.1_39725001_3 - 0.51 10.3 30.3 0.73 9.8 0.9 5.9 2 1 4 6 6 6 0 Protein kinase G rubredoxin domain XPA_N PF01286.16 001280353.1_39725001_3 - 0.72 9.8 42.2 17 5.4 0.2 10.4 11 0 0 11 11 10 0 XPA protein N-terminal zf-C2H2_11 PF16622.3 001280353.1_39725001_3 - 1.5 8.5 48.0 0.45 10.2 0.7 9.9 10 0 0 10 10 10 0 zinc-finger C2H2-type zf-LYAR PF08790.9 001280353.1_39725001_3 - 1.6 8.6 50.7 0.25 11.1 0.5 9.5 10 0 0 10 10 10 0 LYAR-type C2HC zinc finger DUF3268 PF11672.6 001280353.1_39725001_3 - 1.6 8.9 29.9 0.12 12.6 1.2 5.4 4 2 1 6 6 6 0 zinc-finger-containing domain YhfH PF14149.4 001280353.1_39725001_3 - 3.6 7.5 37.1 43 4.1 0.1 10.1 10 0 0 10 10 10 0 YhfH-like protein zf-AN1 PF01428.14 001280353.1_39725001_3 - 7.5 6.7 54.7 12 6.1 0.1 11.1 9 2 2 11 11 10 0 AN1-like Zinc finger zf-trcl PF13451.4 001280353.1_39725001_3 - 7.8 6.4 39.5 4 7.3 0.2 9.7 11 0 0 11 11 10 0 Probable zinc-ribbon domain p450 PF00067.20 001093777.2_39724001_2 - 6.7e-133 443.7 0.1 7.7e-133 443.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Coa1 PF08695.8 001093777.2_39724001_2 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Band_7 PF01145.23 001246403.1_39724001_1 - 3.3e-26 92.2 1.5 4.5e-26 91.8 1.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.6 001246403.1_39724001_1 - 0.03 14.3 0.4 0.053 13.5 0.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 TPR_2 PF07719.15 001205347.1_39724001_3 - 3.7e-22 76.5 31.7 0.00011 22.0 0.8 10.4 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.4 001205347.1_39724001_3 - 5e-21 73.0 22.5 0.00024 20.9 0.3 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.4 001205347.1_39724001_3 - 3.4e-20 72.0 21.3 1.1e-08 35.1 0.4 6.9 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.4 001205347.1_39724001_3 - 8.6e-20 70.9 7.0 0.00014 22.2 0.0 6.9 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.26 001205347.1_39724001_3 - 8.1e-19 66.5 30.3 5.5e-06 25.8 0.4 10.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.4 001205347.1_39724001_3 - 7.9e-18 63.5 5.2 0.0011 19.4 0.0 8.2 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.4 001205347.1_39724001_3 - 4.8e-16 58.0 10.2 0.00075 19.0 0.0 8.0 8 0 0 8 8 8 4 TPR repeat TPR_7 PF13176.4 001205347.1_39724001_3 - 1.4e-12 46.6 7.9 0.0063 16.3 0.2 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.4 001205347.1_39724001_3 - 7.1e-11 41.9 9.7 1.3 9.6 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.4 001205347.1_39724001_3 - 1.3e-10 40.7 8.1 0.39 11.1 0.0 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.4 001205347.1_39724001_3 - 6.1e-09 35.3 19.5 0.026 14.3 0.8 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.4 001205347.1_39724001_3 - 3.7e-08 33.8 9.5 0.078 13.5 0.0 5.8 6 1 1 7 7 5 2 Tetratricopeptide repeat ANAPC3 PF12895.5 001205347.1_39724001_3 - 6.4e-08 32.6 14.1 0.13 12.4 0.8 5.8 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.4 001205347.1_39724001_3 - 1.2e-05 24.5 7.3 0.0031 16.6 0.2 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.6 001205347.1_39724001_3 - 3.7e-05 22.7 5.2 8.9e-05 21.4 0.2 3.2 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_4 PF07721.12 001205347.1_39724001_3 - 0.00019 21.6 0.0 0.36 11.4 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.4 001205347.1_39724001_3 - 0.0013 18.9 2.6 3.8 7.8 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.7 001205347.1_39724001_3 - 0.0077 15.8 8.9 4.3 6.8 0.3 4.4 5 0 0 5 5 4 1 26S proteasome subunit RPN7 ANAPC5 PF12862.5 001205347.1_39724001_3 - 0.011 15.6 5.9 0.054 13.4 0.2 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 Sec16_C PF12931.5 001205347.1_39724001_3 - 0.012 15.2 5.0 1.1 8.7 0.0 3.4 2 2 2 4 4 4 0 Sec23-binding domain of Sec16 Sel1 PF08238.10 001205347.1_39724001_3 - 0.022 15.3 3.2 3.7 8.2 0.0 4.6 5 0 0 5 5 4 0 Sel1 repeat Fis1_TPR_C PF14853.4 001205347.1_39724001_3 - 0.18 11.8 0.0 0.18 11.8 0.0 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF2333 PF10095.7 001205347.1_39724001_3 - 0.48 9.3 3.3 13 4.6 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2333) PPR PF01535.18 001205347.1_39724001_3 - 2.4 8.5 15.9 13 6.2 0.5 5.3 6 0 0 6 6 4 0 PPR repeat DUF4919 PF16266.3 001205347.1_39724001_3 - 2.7 7.8 6.6 0.43 10.4 0.4 2.7 3 1 1 4 4 3 0 Domain of unknown function (DUF4919) Vps39_1 PF10366.7 001205347.1_39724001_3 - 4.6 7.4 7.2 14 5.9 0.1 3.4 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 RRM_1 PF00076.20 001280194.1_39725001_3 - 9.1e-61 201.5 0.1 4.1e-19 68.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001280194.1_39725001_3 - 1.7e-10 40.4 0.0 0.0019 17.6 0.0 3.3 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.10 001280194.1_39725001_3 - 0.00031 20.7 0.0 0.22 11.7 0.0 2.8 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_3 PF08777.9 001280194.1_39725001_3 - 0.0066 16.3 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.3 001280194.1_39725001_3 - 0.015 15.0 0.0 4.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_7 PF16367.3 001280194.1_39725001_3 - 0.031 14.3 0.0 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif Coilin_N PF15862.3 001280399.1_39724001_1 - 2.6 7.7 15.0 5 6.8 15.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus Fes1 PF08609.8 001280399.1_39724001_3 - 0.00038 21.2 2.0 0.00038 21.2 2.0 3.3 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 RTTN_N PF14726.4 001280399.1_39724001_3 - 0.0076 16.9 1.6 1.9 9.2 0.3 2.7 2 0 0 2 2 2 2 Rotatin, an armadillo repeat protein, centriole functioning DUF4704 PF15787.3 001280399.1_39724001_3 - 0.014 14.5 1.0 0.014 14.5 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) HEAT PF02985.20 001280399.1_39724001_3 - 0.029 14.5 0.0 0.71 10.1 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat CENP-B_N PF04218.11 001243843.1_39724001_2 - 1.5e-12 46.8 0.4 4.5e-12 45.3 0.5 1.7 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain DDE_1 PF03184.17 001243843.1_39724001_2 - 3.7e-12 46.1 0.0 9.1e-12 44.8 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.14 001243843.1_39724001_2 - 7.8e-11 41.7 0.1 2.7e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.4 001243843.1_39724001_2 - 6e-06 25.8 0.0 2.2e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_3 PF01381.20 001243843.1_39724001_2 - 0.00031 20.6 0.0 0.00084 19.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix MarR_2 PF12802.5 001243843.1_39724001_2 - 0.00036 20.2 0.0 0.001 18.8 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_37 PF13744.4 001243843.1_39724001_2 - 0.00064 19.5 0.3 0.0012 18.6 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.4 001243843.1_39724001_2 - 0.00093 19.1 0.0 0.003 17.5 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.4 001243843.1_39724001_2 - 0.0019 17.4 0.0 0.0063 15.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.4 001243843.1_39724001_2 - 0.003 17.2 0.1 0.0055 16.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.4 001243843.1_39724001_2 - 0.0052 17.0 0.3 0.02 15.1 0.0 2.2 2 0 0 2 2 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.14 001243843.1_39724001_2 - 0.0061 15.9 0.1 0.013 14.9 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_26 PF13443.4 001243843.1_39724001_2 - 0.0076 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Trp_repressor PF01371.17 001243843.1_39724001_2 - 0.012 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Trp repressor protein HTH_19 PF12844.5 001243843.1_39724001_2 - 0.028 14.4 0.1 0.068 13.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.4 001243843.1_39724001_2 - 0.037 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_5 PF01022.18 001243843.1_39724001_2 - 0.04 13.6 0.2 0.08 12.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.4 001243843.1_39724001_2 - 0.055 12.9 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MRP-L20 PF12824.5 001243843.1_39724001_2 - 0.079 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 HTH_7 PF02796.13 001243843.1_39724001_2 - 0.16 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Peptidase_M19 PF01244.19 001280027.2_39724001_1 - 3.4e-102 341.7 0.0 4.2e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) LBP_BPI_CETP PF01273.23 001243277.2_39723001_2 - 7.5e-32 110.1 4.9 7.5e-32 110.1 4.9 1.6 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain Myc_target_1 PF15179.4 001242619.2_39722001_1 - 0.0011 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Myc target protein 1 DUF1180 PF06679.10 001242619.2_39722001_1 - 0.1 12.9 0.0 7.5 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TMEM154 PF15102.4 001242619.2_39722001_1 - 0.17 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family 2-oxoacid_dh PF00198.21 001142759.1_39725001_3 - 4.5e-75 252.0 0.0 8.1e-59 198.8 0.0 2.2 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.20 001142759.1_39725001_3 - 2.4e-20 72.0 0.1 4.4e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.15 001142759.1_39725001_3 - 1e-15 57.7 0.1 1.9e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.4 001142759.1_39725001_3 - 0.016 14.9 0.1 4.1 7.2 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like TPT PF03151.14 001280116.1_39724001_2 - 2.8e-22 79.3 9.9 3.5e-22 79.0 9.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.18 001280116.1_39724001_2 - 1.2e-07 31.8 29.1 1.4e-05 25.2 10.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.9 001280116.1_39724001_2 - 4.7e-06 25.9 16.3 6.3e-06 25.5 16.3 1.1 1 0 0 1 1 1 1 UAA transporter family SRTM1 PF15872.3 001280116.1_39724001_2 - 10 6.2 7.2 8.9 6.4 2.9 2.6 2 1 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 DUF1640 PF07798.9 001280260.1_39723001_3 - 5.3e-58 195.8 14.9 1.1e-57 194.8 14.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) JAKMIP_CC3 PF16034.3 001280260.1_39723001_3 - 0.00034 20.5 9.0 0.00049 20.0 9.0 1.2 1 0 0 1 1 1 1 JAKMIP CC3 domain MHC_I_2 PF14586.4 001280260.1_39723001_3 - 0.083 12.6 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 DUF972 PF06156.11 001280260.1_39723001_3 - 9.5 6.8 15.0 4.1 8.0 5.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Tetraspannin PF00335.18 001280411.1_39724001_3 - 1.2e-39 136.2 10.2 1.7e-39 135.7 10.2 1.2 1 0 0 1 1 1 1 Tetraspanin family ERM PF00769.17 001243904.2_39727001_1 - 7.9e-05 22.5 0.3 7.9e-05 22.5 0.3 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family tRNA-synt_2 PF00152.18 001246373.1_39726001_3 - 1.3e-107 359.4 0.0 2e-107 358.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.23 001246373.1_39726001_3 - 1.8e-10 40.6 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CALCOCO1 PF07888.9 001280442.1_39726001_3 - 3.2e-88 296.7 66.0 2.9e-86 290.3 36.4 3.4 2 1 1 3 3 3 3 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C2H2_4 PF13894.4 001280442.1_39726001_3 - 0.02 15.5 5.9 0.81 10.5 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.10 001280442.1_39726001_3 - 0.23 11.6 4.1 1.1 9.5 4.1 2.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding UBZ_FAAP20 PF15750.3 001280442.1_39726001_3 - 0.49 10.3 6.0 1.3 8.9 1.1 2.7 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger ubiquitin PF00240.21 001280442.1_39726001_3 - 6.8 6.4 11.8 0.31 10.6 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin family Ank_2 PF12796.5 001205040.2_39725001_2 - 7.3e-51 170.6 2.8 4.9e-17 62.2 0.1 5.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001205040.2_39725001_2 - 7e-45 150.7 6.3 4.5e-10 39.7 0.0 7.2 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.28 001205040.2_39725001_2 - 1.4e-37 126.4 10.3 2.2e-06 27.7 0.0 10.6 9 2 2 11 11 11 8 Ankyrin repeat Ank_3 PF13606.4 001205040.2_39725001_2 - 1.3e-34 114.2 6.3 0.00012 22.1 0.0 10.7 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.4 001205040.2_39725001_2 - 9.2e-26 89.4 8.1 2e-06 27.9 0.2 8.3 3 2 7 10 10 10 8 Ankyrin repeats (many copies) SOCS_box PF07525.14 001205040.2_39725001_2 - 1.3e-11 44.5 6.2 1.8e-11 44.0 4.8 2.0 2 0 0 2 2 2 1 SOCS box UPF0524 PF15823.3 001205040.2_39725001_3 - 4.3 6.5 5.6 6.6 5.9 5.6 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 Y_phosphatase PF00102.25 001280467.1_39725001_2 - 2.4e-84 282.4 0.1 3.7e-84 281.8 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.18 001280467.1_39725001_2 - 4.1e-31 107.7 0.0 7.2e-30 103.7 0.0 2.3 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.4 001280467.1_39725001_2 - 4.4e-11 42.9 0.0 8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Y_phosphatase3 PF13350.4 001280467.1_39725001_2 - 0.019 14.8 0.0 0.048 13.5 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.4 001280467.1_39725001_2 - 0.062 13.3 0.1 0.22 11.5 0.1 1.9 1 1 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.18 001280467.1_39725001_2 - 0.064 12.9 2.7 0.08 12.6 0.9 2.2 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain CRAL_TRIO_N PF03765.13 001280467.1_39725001_2 - 0.15 12.1 0.1 0.49 10.5 0.1 1.9 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain Tmemb_170 PF10190.7 001251955.2_39723001_3 - 3.1e-40 136.7 7.1 5.2e-40 136.0 7.1 1.4 1 0 0 1 1 1 1 Putative transmembrane protein 170 zf-C3HC4_4 PF15227.4 001205177.1_39725001_2 - 2.7e-11 43.3 6.9 9.5e-11 41.6 6.9 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.4 001205177.1_39725001_2 - 3.2e-10 39.7 6.3 1.2e-09 37.9 6.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger SPRY PF00622.26 001205177.1_39725001_2 - 5.4e-10 39.3 0.5 1.2e-09 38.2 0.1 1.7 2 0 0 2 2 1 1 SPRY domain zf-C3HC4 PF00097.23 001205177.1_39725001_2 - 2.9e-09 36.5 5.6 9.3e-09 34.9 5.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.22 001205177.1_39725001_2 - 6.9e-08 32.4 4.9 6.9e-08 32.4 4.9 3.0 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4_2 PF13923.4 001205177.1_39725001_2 - 2.2e-06 27.3 5.9 1e-05 25.1 5.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001205177.1_39725001_2 - 5.2e-06 26.5 5.1 5.2e-06 26.5 5.1 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.4 001205177.1_39725001_2 - 7.9e-06 25.5 3.7 7.9e-06 25.5 3.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.4 001205177.1_39725001_2 - 2.7e-05 23.9 3.8 2.7e-05 23.9 3.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.3 001205177.1_39725001_2 - 0.00018 21.4 3.3 0.00018 21.4 3.3 3.0 2 1 1 3 3 3 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.4 001205177.1_39725001_2 - 1.3 8.8 12.4 1.3 8.8 8.9 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Exonuc_VII_L PF02601.13 001205177.1_39725001_2 - 3.3 7.0 8.3 4.7 6.5 8.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2951 PF11166.6 001205177.1_39725001_2 - 4.5 7.4 8.3 1.3 9.2 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) TMPIT PF07851.11 001205177.1_39725001_2 - 7.8 5.5 12.3 15 4.5 12.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein Ras PF00071.20 001280325.1_39725001_1 - 1.9e-51 173.7 0.0 2.5e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001280325.1_39725001_1 - 3.9e-18 65.7 0.0 5.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001280325.1_39725001_1 - 3.4e-08 33.0 0.0 5.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.3 001280325.1_39725001_1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial PMP22_Claudin PF00822.18 001246413.1_39725001_2 - 6.6e-20 71.5 8.7 1.2e-19 70.6 8.7 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.4 001246413.1_39725001_2 - 0.031 13.9 15.6 0.74 9.4 15.0 2.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Bclt PF15318.4 001044379.1_39722001_3 - 1.4e-29 103.3 9.6 3.8e-16 59.4 1.9 2.2 1 1 1 2 2 2 2 Putative Bcl-2 like protein of testis DUF1126 PF06565.10 001280343.1_39725001_1 - 4e-101 331.7 4.4 3.3e-35 119.9 0.2 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.4 001280343.1_39725001_1 - 0.00014 22.1 0.1 0.00051 20.3 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.30 001280343.1_39725001_1 - 0.00045 19.4 0.9 0.0039 16.5 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.4 001280343.1_39725001_1 - 0.00047 19.8 0.4 0.0026 17.4 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain NLPC_P60 PF00877.17 001280343.1_39725001_1 - 0.12 12.3 0.0 6 6.8 0.0 2.4 2 0 0 2 2 2 0 NlpC/P60 family PX PF00787.22 001246533.1_39724001_3 - 9e-19 67.4 1.6 9e-19 67.4 0.1 1.8 2 0 0 2 2 2 1 PX domain DUF641 PF04859.10 001246533.1_39724001_3 - 0.0032 17.7 2.0 0.027 14.7 1.6 2.2 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) ADIP PF11559.6 001246533.1_39724001_3 - 0.45 10.5 6.8 0.81 9.6 6.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-H2C2_2 PF13465.4 001280199.1_39726001_1 - 1.3e-63 208.6 82.9 2.2e-08 34.0 0.8 15.0 15 0 0 15 15 15 10 Zinc-finger double domain zf-C2H2 PF00096.24 001280199.1_39726001_1 - 1.6e-52 173.0 85.7 6.8e-06 26.1 0.5 13.4 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280199.1_39726001_1 - 4.7e-41 135.8 86.5 0.00042 20.8 0.5 13.9 13 1 1 14 14 13 12 C2H2-type zinc finger BTB PF00651.29 001280199.1_39726001_1 - 2.3e-28 98.5 0.9 4.7e-28 97.5 0.9 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_11 PF16622.3 001280199.1_39726001_1 - 5.8e-20 70.6 48.9 1.7e-05 24.3 0.3 11.3 12 0 0 12 12 12 6 zinc-finger C2H2-type zf-C2H2_jaz PF12171.6 001280199.1_39726001_1 - 1.2e-17 63.6 45.8 0.0027 17.8 0.0 12.3 13 0 0 13 13 13 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.5 001280199.1_39726001_1 - 5.9e-11 42.3 57.0 0.21 11.9 1.0 11.6 11 0 0 11 11 11 6 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.4 001280199.1_39726001_1 - 3.8e-05 23.2 70.5 0.012 15.3 0.5 12.6 12 2 0 12 12 11 6 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.8 001280199.1_39726001_1 - 0.00022 21.2 56.8 0.31 11.1 4.5 8.7 4 3 5 9 9 9 4 Zinc ribbon domain zinc_ribbon_15 PF17032.3 001280199.1_39726001_1 - 0.00029 21.4 40.7 0.29 11.8 2.1 6.9 3 2 2 7 7 7 4 zinc-ribbon family zinc_ribbon_9 PF14369.4 001280199.1_39726001_1 - 0.0011 19.0 25.9 1.9 8.7 0.1 9.1 9 0 0 9 9 9 1 zinc-ribbon zf-C2HC_2 PF13913.4 001280199.1_39726001_1 - 0.0037 17.0 35.7 0.24 11.2 0.1 8.7 9 0 0 9 9 8 3 zinc-finger of a C2HC-type zf-Di19 PF05605.10 001280199.1_39726001_1 - 0.0065 16.6 3.7 0.0065 16.6 3.7 7.4 4 2 5 9 9 8 4 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.13 001280199.1_39726001_1 - 0.02 14.8 53.9 0.27 11.2 0.8 9.8 3 2 7 10 10 10 0 BED zinc finger XPA_N PF01286.16 001280199.1_39726001_1 - 0.023 14.6 53.0 1 9.3 0.1 11.6 12 0 0 12 12 12 0 XPA protein N-terminal Packaging_FI PF14000.4 001280199.1_39726001_1 - 0.024 15.0 1.9 0.024 15.0 1.9 2.4 3 0 0 3 3 1 0 DNA packaging protein FI zf-C2H2_6 PF13912.4 001280199.1_39726001_1 - 0.025 14.4 74.2 0.61 10.0 0.4 12.5 13 0 0 13 13 13 0 C2H2-type zinc finger zf-C2HE PF16278.3 001280199.1_39726001_1 - 0.037 14.3 0.7 0.037 14.3 0.7 10.7 2 1 7 9 9 7 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.17 001280199.1_39726001_1 - 0.042 13.7 37.6 0.62 10.0 2.6 7.2 2 1 5 7 7 7 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3268 PF11672.6 001280199.1_39726001_1 - 0.11 12.7 29.6 1.3 9.3 0.5 6.0 4 2 2 6 6 6 0 zinc-finger-containing domain C1_1 PF00130.20 001280199.1_39726001_1 - 0.12 12.1 40.4 12 5.7 2.9 8.7 3 2 6 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_9 PF16293.3 001280199.1_39726001_1 - 1.9 8.3 20.2 2 8.2 0.2 5.5 7 0 0 7 7 5 0 C2H2 type zinc-finger (1 copy) TerY_C PF15616.4 001280199.1_39726001_1 - 6.7 6.7 18.2 0.25 11.3 0.9 3.6 1 1 2 3 3 3 0 TerY-C metal binding domain zf-C2H2_2 PF12756.5 001280199.1_39726001_1 - 7.2 6.9 49.5 1.7 8.9 6.9 9.0 2 1 5 8 8 8 0 C2H2 type zinc-finger (2 copies) PIG-U PF06728.11 001280440.1_39724001_3 - 2.2e-115 385.7 46.5 2.6e-115 385.4 46.5 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Chon_Sulph_att PF06566.9 001246417.1_39724001_3 - 2.6e-111 371.3 23.4 4.1e-111 370.7 23.4 1.3 1 0 0 1 1 1 1 Chondroitin sulphate attachment domain Neural_ProG_Cyt PF06567.9 001246417.1_39724001_3 - 7.5e-44 148.6 5.6 9.6e-23 80.5 0.6 2.3 1 1 1 2 2 2 2 Neural chondroitin sulphate proteoglycan cytoplasmic domain Glyco_transf_10 PF00852.17 001009149.1_39723001_1 - 5.5e-68 228.0 0.7 7.2e-68 227.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.3 001009149.1_39723001_1 - 5e-36 123.4 0.0 9.4e-36 122.5 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DUF2076 PF09849.7 001009149.1_39723001_3 - 0.02 14.8 2.1 0.032 14.1 2.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) XRCC4 PF06632.10 001280398.1_39724001_1 - 2.8e-157 522.7 8.2 3.2e-157 522.5 8.2 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF927 PF06048.9 001280398.1_39724001_1 - 0.079 12.3 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) YkyA PF10368.7 001280398.1_39724001_1 - 4.7 6.8 12.5 0.21 11.2 5.9 2.1 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein ACBP PF00887.17 001280108.1_39724001_2 - 1.3e-25 89.3 0.1 2.7e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein MAGE_N PF12440.6 001328310.1_39724001_1 - 1.2e-23 83.4 16.4 1.2e-23 83.4 16.4 1.9 1 1 1 2 2 2 1 Melanoma associated antigen family N terminal MAGE PF01454.17 001328310.1_39724001_1 - 3.2e-13 49.7 2.0 2.4e-09 37.1 0.0 2.6 2 1 1 3 3 3 2 MAGE family RRM_3 PF08777.9 001280418.1_39724001_2 - 6.6e-33 112.7 2.2 6.6e-33 112.7 2.2 3.5 2 1 1 3 3 3 2 RNA binding motif La PF05383.15 001280418.1_39724001_2 - 2.9e-22 78.3 0.7 9.3e-22 76.7 0.1 2.0 2 0 0 2 2 2 1 La domain RRM_1 PF00076.20 001280418.1_39724001_2 - 1.2e-14 53.8 0.3 1.6e-10 40.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGK PF00162.17 001328313.1_39724001_2 - 5.9e-146 486.1 0.1 6.8e-146 485.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Abhydrolase_1 PF00561.18 001280482.1_39725001_2 - 8.6e-10 38.5 0.2 2.8e-09 36.8 0.2 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001280482.1_39725001_2 - 7.1e-05 22.1 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.19 001280482.1_39725001_2 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family RRM_5 PF13893.4 001280158.1_39724001_1 - 1.1e-61 205.9 1.0 1.9e-54 182.5 0.1 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.20 001280158.1_39724001_1 - 5.7e-22 77.2 0.3 3.7e-06 26.5 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001280158.1_39724001_1 - 7e-05 22.5 0.1 1.3 8.8 0.0 3.3 3 0 0 3 3 3 3 Occluded RNA-recognition motif Limkain-b1 PF11608.6 001280158.1_39724001_1 - 0.00076 19.4 0.1 1.6 8.7 0.0 3.2 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.9 001280158.1_39724001_1 - 0.008 16.1 0.0 0.051 13.5 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Radial_spoke PF04712.10 001280377.1_39725001_2 - 3.3e-198 659.5 6.1 3.3e-198 659.5 6.1 1.9 1 1 1 2 2 2 1 Radial spokehead-like protein Dpy-30 PF05186.11 001280377.1_39725001_2 - 0.13 11.9 0.1 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 Dpy-30 motif Ras PF00071.20 001246383.1_39724001_2 - 1.3e-61 206.8 0.3 1.7e-61 206.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001246383.1_39724001_2 - 8e-35 119.5 0.0 1.3e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001246383.1_39724001_2 - 9.4e-12 44.6 0.0 1.3e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001246383.1_39724001_2 - 0.00024 20.4 0.0 0.00033 20.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.21 001246383.1_39724001_2 - 0.00057 19.8 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001246383.1_39724001_2 - 0.007 16.1 0.7 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001246383.1_39724001_2 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.4 001246383.1_39724001_2 - 0.1 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Alveol-reg_P311 PF11092.6 001246414.1_39725001_3 - 4.3e-34 116.3 0.0 7.8e-34 115.5 0.0 1.4 1 0 0 1 1 1 1 Neuronal protein 3.1 (p311) SIR2 PF02146.15 001280155.1_39725001_2 - 1.3e-54 184.7 0.0 1.7e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family YdjO PF14169.4 001280155.1_39725001_2 - 0.049 13.2 0.3 0.093 12.3 0.3 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO RecQ_Zn_bind PF16124.3 001280155.1_39725001_2 - 1.2 9.7 3.2 9.4 6.9 0.2 2.4 2 0 0 2 2 2 0 RecQ zinc-binding Asp_protease_2 PF13650.4 001302445.1_39729001_1 - 0.00076 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001302445.1_39729001_1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001302445.1_39729001_1 - 0.052 14.0 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001302445.1_39729001_2 - 5.4e-15 55.1 0.0 9.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001302445.1_39729001_2 - 1.3e-14 54.1 1.9 5e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001302445.1_39729001_2 - 0.00037 20.5 0.1 0.00065 19.7 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001302445.1_39729001_2 - 0.002 17.9 4.7 0.0032 17.2 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001302445.1_39729001_2 - 0.0027 17.2 0.2 0.0064 16.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001302445.1_39729001_2 - 0.0068 16.2 0.4 0.011 15.5 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 CCDC106 PF15794.3 001302445.1_39729001_2 - 0.14 11.7 3.8 0.55 9.8 2.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CENP-H PF05837.10 001302445.1_39729001_2 - 0.24 11.7 4.8 0.47 10.8 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.10 001302445.1_39729001_2 - 0.33 11.3 9.2 0.67 10.3 9.2 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001302445.1_39729001_2 - 0.33 11.4 3.8 0.79 10.3 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001302445.1_39729001_2 - 0.37 9.5 3.4 0.65 8.7 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.3 001302445.1_39729001_2 - 0.38 11.0 3.9 0.68 10.2 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) LPP PF04728.11 001302445.1_39729001_2 - 0.62 10.4 2.1 1.3 9.4 2.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper SHE3 PF17078.3 001302445.1_39729001_2 - 0.79 9.3 7.3 1.6 8.3 7.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001302445.1_39729001_2 - 1.2 8.8 5.9 2.3 7.9 5.9 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001302445.1_39729001_2 - 1.5 8.8 8.4 3.3 7.8 8.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 001302445.1_39729001_2 - 1.6 8.3 5.3 3.2 7.4 5.3 1.4 1 0 0 1 1 1 0 IncA protein TSC22 PF01166.16 001302445.1_39729001_2 - 7 6.9 7.5 39 4.5 7.5 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family Paralemmin PF03285.13 001280283.1_39724001_1 - 2.5e-55 188.2 19.9 1.9e-54 185.3 19.9 2.1 1 1 0 1 1 1 1 Paralemmin Cob_adeno_trans PF01923.16 001280283.1_39724001_1 - 0.044 13.8 1.0 0.084 12.9 1.0 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase V_ATPase_I PF01496.17 001280283.1_39724001_1 - 8.1 4.1 9.4 13 3.4 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ASCH PF04266.12 001328323.1_39724001_3 - 4.8e-13 49.5 0.0 2e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 ASCH domain zf-C2HC5 PF06221.11 001328323.1_39724001_3 - 1.4e-10 40.9 11.2 3e-10 39.8 11.2 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type UxaC PF02614.12 001328323.1_39724001_3 - 0.046 12.4 0.2 0.13 10.9 0.0 1.7 2 0 0 2 2 2 0 Glucuronate isomerase Rad10 PF03834.12 001194931.1_39722001_1 - 8.3e-52 173.9 0.0 1.4e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.4 001194931.1_39722001_1 - 7.9e-07 29.5 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.21 001194931.1_39722001_1 - 3.5e-06 26.5 0.0 6.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.5 001194931.1_39722001_1 - 2.2e-05 24.3 0.0 4.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif FliG_N PF14842.4 001194931.1_39722001_1 - 0.17 12.3 0.0 0.46 10.9 0.0 1.7 1 1 0 1 1 1 0 FliG N-terminal domain TEX19 PF15553.4 001246469.1_39724001_2 - 7e-83 276.2 12.3 1.5e-82 275.2 7.0 2.2 2 0 0 2 2 2 2 Testis-expressed protein 19 His_Phos_1 PF00300.20 001280257.1_39725001_3 - 2e-31 109.1 0.0 2.7e-24 85.8 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Exc PF07825.9 001280257.1_39725001_3 - 0.069 13.0 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Excisionase-like protein zf-H2C2_2 PF13465.4 001246631.1_39727001_1 - 2e-101 328.1 111.9 1.6e-08 34.5 1.2 18.1 18 1 1 19 19 19 15 Zinc-finger double domain zf-C2H2 PF00096.24 001246631.1_39727001_1 - 7.7e-68 221.2 124.0 2.1e-07 30.8 1.0 16.8 17 0 0 17 17 17 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001246631.1_39727001_1 - 2.5e-40 133.5 115.7 0.00043 20.8 1.0 17.1 17 0 0 17 17 17 12 C2H2-type zinc finger KRAB PF01352.25 001246631.1_39727001_1 - 1.7e-24 85.1 0.1 3.9e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001246631.1_39727001_1 - 1.4e-19 69.4 87.1 0.019 14.8 1.2 14.5 15 0 0 15 15 15 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001246631.1_39727001_1 - 6.2e-15 54.9 75.5 0.0015 18.6 0.1 14.8 16 0 0 16 16 16 7 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001246631.1_39727001_1 - 1.3e-13 50.3 64.5 0.0035 16.9 0.8 13.4 13 0 0 13 13 13 7 zinc-finger C2H2-type XPA_N PF01286.16 001246631.1_39727001_1 - 1e-07 31.7 63.3 1.8 8.5 0.2 13.3 13 0 0 13 13 13 5 XPA protein N-terminal Zn-ribbon_8 PF09723.8 001246631.1_39727001_1 - 1.2e-07 31.6 70.1 0.06 13.4 4.4 10.5 6 4 6 13 13 13 9 Zinc ribbon domain zf-trcl PF13451.4 001246631.1_39727001_1 - 2.7e-05 23.8 52.5 1.5 8.7 3.6 12.0 11 2 0 11 11 11 4 Probable zinc-ribbon domain C1_1 PF00130.20 001246631.1_39727001_1 - 0.00021 21.0 43.5 0.4 10.5 0.7 8.3 1 1 9 10 10 10 4 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.3 001246631.1_39727001_1 - 0.00082 19.9 62.3 0.13 12.9 2.1 8.1 3 1 6 9 9 9 5 zinc-ribbon family PKcGMP_CC PF16808.3 001246567.1_39724001_3 - 7.7 6.3 14.7 0.049 13.4 4.9 2.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UIM PF02809.18 001280463.1_39726001_2 - 0.0098 15.6 11.2 0.044 13.6 2.3 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif Rad50_zn_hook PF04423.12 001280463.1_39726001_2 - 0.033 13.9 6.2 0.24 11.2 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif ig PF00047.23 001105155.1_39723001_1 - 6e-19 67.9 0.0 2.9e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001105155.1_39723001_1 - 1.2e-07 32.1 0.0 0.0022 18.4 0.0 3.1 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.4 001105155.1_39723001_1 - 3.1e-07 30.5 0.0 0.0016 18.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain SIT PF15330.4 001105155.1_39723001_1 - 0.00031 21.0 0.1 0.0013 19.0 0.0 2.1 2 1 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT DEAD PF00270.27 001246450.1_39724001_3 - 1.8e-29 102.6 0.0 3.7e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001246450.1_39724001_3 - 3.8e-27 94.7 0.1 7.7e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001246450.1_39724001_3 - 0.00085 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.23 001280114.1_39724001_3 - 2.2e-62 210.7 0.0 4.1e-62 209.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280114.1_39724001_3 - 1.8e-29 102.7 0.0 2.9e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001280114.1_39724001_3 - 0.00047 19.4 0.0 0.00067 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.4 001280114.1_39724001_3 - 0.016 14.7 0.2 0.055 13.0 0.1 1.7 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RNA_pol_Rpc4 PF05132.12 001280429.1_39725001_1 - 0.18 12.1 10.2 0.3 11.4 10.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 EOS1 PF12326.6 001280429.1_39725001_1 - 0.25 11.1 1.0 0.32 10.8 1.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein Presenilin PF01080.15 001280429.1_39725001_1 - 2.8 6.4 4.7 3.6 6.1 4.7 1.1 1 0 0 1 1 1 0 Presenilin PGI PF00342.17 001280429.1_39725001_2 - 4e-268 889.7 0.0 4.9e-268 889.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase FAM176 PF14851.4 001280429.1_39725001_2 - 0.032 13.8 2.3 0.057 13.0 2.3 1.4 1 0 0 1 1 1 0 FAM176 family EOS1 PF12326.6 001280429.1_39725001_2 - 0.14 11.9 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 N-glycosylation protein Connexin PF00029.17 001280429.1_39725001_2 - 3.6 7.2 14.5 5.1 6.7 14.5 1.2 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.12 001280429.1_39725001_2 - 5.9 6.5 13.0 13 5.3 13.0 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RNA_pol_Rpc4 PF05132.12 001280429.1_39725001_2 - 6.8 7.0 14.0 12 6.2 14.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 UreE_N PF02814.13 001246389.1_39725001_1 - 0.091 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Proteasome PF00227.24 001246389.1_39725001_3 - 1.3e-39 135.5 0.0 1.8e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit ubiquitin PF00240.21 001252599.1_39722001_3 - 1.1e-34 117.8 0.3 2e-34 117.0 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.17 001252599.1_39722001_3 - 3.8e-28 97.2 4.2 8e-28 96.2 4.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.6 001252599.1_39722001_3 - 8.7e-17 60.6 0.4 1.7e-16 59.7 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001252599.1_39722001_3 - 4.7e-06 26.8 0.7 3.3e-05 24.1 0.2 2.6 2 1 1 3 3 3 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.4 001252599.1_39722001_3 - 0.00021 21.2 0.7 0.00042 20.3 0.7 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001252599.1_39722001_3 - 0.009 16.4 0.6 0.013 16.0 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.19 001252599.1_39722001_3 - 0.046 13.8 3.6 0.082 13.0 3.6 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain UPF0113 PF03657.11 001246425.1_39724001_2 - 3.7e-06 26.9 0.0 5.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.18 001246425.1_39724001_2 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 PUA domain PP1 PF07430.9 001246425.1_39724001_2 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain PolyA_pol PF01743.18 001280435.1_39724001_1 - 7.3e-32 110.3 0.3 1.1e-31 109.7 0.3 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.5 001280435.1_39724001_1 - 1.7e-10 40.4 0.0 5.3e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Glyco_transf_43 PF03360.14 001037314.1_39722001_1 - 2.4e-70 236.4 0.0 2.8e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 EF-hand_7 PF13499.4 001246592.1_39727001_2 - 2.9e-14 53.1 23.0 0.00035 20.9 3.1 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.30 001246592.1_39727001_2 - 1.9e-13 48.8 23.8 0.004 16.5 0.4 7.1 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.4 001246592.1_39727001_2 - 1.1e-11 43.6 17.8 0.0067 16.2 0.1 6.9 7 0 0 7 7 7 5 EF-hand domain EF-hand_5 PF13202.4 001246592.1_39727001_2 - 2e-10 39.6 27.1 0.011 15.1 0.6 6.8 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.4 001246592.1_39727001_2 - 3.1e-05 23.5 11.6 0.0035 16.9 0.0 4.6 5 0 0 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001246592.1_39727001_2 - 3.5 7.9 13.9 7.3 6.8 0.2 3.7 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region LTV PF04180.12 001280157.1_39724001_2 - 1.4e-85 288.2 23.0 9.3e-85 285.5 23.0 2.1 1 1 0 1 1 1 1 Low temperature viability protein UPF0767 PF15990.3 001280157.1_39724001_2 - 5.1 7.2 5.2 16 5.6 5.2 1.9 1 0 0 1 1 1 0 UPF0767 family OTU PF02338.17 001280313.1_39725001_1 - 2.4e-05 24.7 0.0 3.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.5 001280313.1_39725001_1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ubiquitin_2 PF14560.4 001280313.1_39725001_1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DSPn PF14671.4 001280195.1_39725001_1 - 3.3e-61 205.7 2.4 4.2e-61 205.4 1.0 1.9 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.18 001280195.1_39725001_1 - 8.7e-13 48.1 0.2 2.2e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.4 001280195.1_39725001_1 - 4.7e-06 26.7 0.0 7.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.25 001280195.1_39725001_1 - 3.1e-05 23.5 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.4 001280195.1_39725001_1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family 7tm_1 PF00001.19 001205039.1_39725001_1 - 1.5e-17 63.5 14.8 2.5e-17 62.9 14.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Methyltransf_32 PF13679.4 001280209.1_39725001_2 - 7e-09 35.7 8.5 1.5e-08 34.7 5.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.4 001280209.1_39725001_2 - 2.9e-08 33.5 0.0 6.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.13 001280209.1_39725001_2 - 8.5e-06 25.1 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G TRM13 PF05206.12 001280209.1_39725001_2 - 0.00026 20.5 5.9 0.11 11.9 1.2 2.9 2 1 1 3 3 3 2 Methyltransferase TRM13 MTS PF05175.12 001280209.1_39725001_2 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain GST_C_3 PF14497.4 001280209.1_39725001_2 - 0.0011 19.0 0.0 0.0036 17.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.4 001280209.1_39725001_2 - 0.0015 19.1 0.0 0.0038 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GST_C_2 PF13410.4 001280209.1_39725001_2 - 0.0018 18.1 0.0 0.0072 16.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ubie_methyltran PF01209.16 001280209.1_39725001_2 - 0.0053 16.0 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.15 001280209.1_39725001_2 - 0.0081 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.7 001280209.1_39725001_2 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GST_C PF00043.23 001280209.1_39725001_2 - 0.038 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BSMAP PF12280.6 001243112.1_39724001_3 - 1.4e-69 233.8 1.0 1.4e-69 233.8 1.0 2.1 2 0 0 2 2 2 1 Brain specific membrane anchored protein HSP70 PF00012.18 001246372.1_39724001_3 - 2.3e-115 386.0 0.0 2.7e-115 385.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.11 001246372.1_39724001_3 - 5.7e-11 41.7 0.0 4.5e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Actin PF00022.17 001246372.1_39724001_3 - 0.0087 14.6 0.0 0.19 10.2 0.1 2.2 2 0 0 2 2 2 1 Actin ArAE_2 PF10334.7 001246372.1_39724001_3 - 0.098 12.4 0.0 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Aromatic acid exporter family member 2 TPR_2 PF07719.15 001280187.1_39725001_3 - 3.1e-38 126.7 19.1 4.2e-05 23.2 0.0 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.26 001280187.1_39725001_3 - 3.3e-34 115.2 23.9 2.7e-05 23.6 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.4 001280187.1_39725001_3 - 1.2e-28 96.7 21.0 4.9e-06 26.2 0.0 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.4 001280187.1_39725001_3 - 4.4e-23 80.6 17.2 5.4e-09 35.5 0.0 7.9 3 2 7 10 10 10 5 TPR repeat TPR_19 PF14559.4 001280187.1_39725001_3 - 8.1e-20 71.0 11.7 2.2e-05 24.7 0.1 6.0 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.4 001280187.1_39725001_3 - 7.2e-18 64.5 18.2 2.7e-06 27.4 0.2 6.8 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.4 001280187.1_39725001_3 - 6.1e-16 57.6 1.8 0.00085 19.8 0.0 7.3 3 3 5 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.4 001280187.1_39725001_3 - 1e-15 57.9 0.1 0.038 14.6 0.4 5.7 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.4 001280187.1_39725001_3 - 7.1e-15 54.1 15.5 0.012 15.8 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.4 001280187.1_39725001_3 - 4.5e-13 49.0 0.0 0.00074 19.5 0.0 5.2 2 2 4 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.5 001280187.1_39725001_3 - 5.4e-13 48.8 26.0 5.9e-05 23.1 1.5 6.1 2 2 4 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.4 001280187.1_39725001_3 - 9.6e-10 38.3 11.6 2.8 8.6 0.0 9.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.4 001280187.1_39725001_3 - 3.4e-09 35.9 11.0 0.0018 18.0 0.0 8.3 10 0 0 10 10 9 1 Tetratricopeptide repeat Wzy_C_2 PF11846.6 001280187.1_39725001_3 - 9.1e-07 28.8 3.2 0.082 12.7 0.0 4.1 2 2 2 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal PknG_TPR PF16918.3 001280187.1_39725001_3 - 2.5e-06 26.3 0.2 0.034 12.8 0.1 2.5 3 0 0 3 3 3 2 Protein kinase G tetratricopeptide repeat TPR_15 PF13429.4 001280187.1_39725001_3 - 3e-06 26.5 6.6 0.0072 15.4 0.1 4.1 1 1 2 3 3 3 3 Tetratricopeptide repeat NARP1 PF12569.6 001280187.1_39725001_3 - 6.9e-05 21.8 6.7 0.0093 14.8 0.2 3.8 2 1 3 5 5 5 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.4 001280187.1_39725001_3 - 0.0074 16.5 5.3 1.1 9.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.15 001280187.1_39725001_3 - 0.015 15.6 5.6 14 6.0 1.6 4.0 3 1 1 4 4 4 0 Bacterial transcriptional activator domain ChAPs PF09295.8 001280187.1_39725001_3 - 0.021 13.7 1.3 1.2 8.0 0.1 2.8 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.4 001280187.1_39725001_3 - 0.023 14.5 20.7 8.1 6.4 0.1 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF3808 PF10300.7 001280187.1_39725001_3 - 0.028 13.0 6.1 0.057 12.0 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3808) Mu-like_Pro PF10123.7 001280187.1_39725001_3 - 0.048 13.0 1.2 0.28 10.5 0.8 2.1 1 1 1 2 2 2 0 Mu-like prophage I protein Coatomer_E PF04733.12 001280187.1_39725001_3 - 0.53 9.5 6.9 1.9 7.7 0.5 3.0 2 2 1 3 3 3 0 Coatomer epsilon subunit NYD-SP12_N PF15015.4 001246421.1_39725001_2 - 0 1142.2 7.0 0 1142.0 7.0 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_2 PF07719.15 001246421.1_39725001_2 - 0.00052 19.8 2.1 0.51 10.5 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.26 001246421.1_39725001_2 - 0.0022 17.6 0.5 1.3 8.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.4 001246421.1_39725001_2 - 0.12 12.5 1.3 22 5.3 0.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat eIF-5_eIF-2B PF01873.15 001098556.1_39723001_1 - 2.5e-41 140.1 0.2 4.2e-41 139.3 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 FGF PF00167.16 001280471.1_39725001_1 - 6.4e-42 142.5 0.2 1e-41 141.8 0.2 1.3 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.11 001280471.1_39725001_1 - 0.016 15.3 0.0 0.065 13.3 0.0 1.9 2 0 0 2 2 2 0 Fascin domain zf-HC5HC2H PF13771.4 001246542.1_39725001_3 - 6.8e-18 64.6 4.4 6.8e-18 64.6 4.4 3.5 3 1 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.4 001246542.1_39725001_3 - 2e-08 34.2 2.9 2e-08 34.2 2.9 3.5 2 2 1 3 3 3 1 PHD-zinc-finger like domain RITA PF17066.3 001280118.1_39724001_1 - 2e-130 434.0 19.8 2.5e-130 433.7 19.8 1.1 1 0 0 1 1 1 1 RBPJ-interacting and tubulin associated protein PAP2_C PF14360.4 001280318.1_39724001_2 - 1.4e-27 95.9 14.6 1.4e-27 95.9 14.6 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.19 001280318.1_39724001_2 - 5.5e-07 29.3 7.1 5.5e-07 29.3 7.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily SAM_1 PF00536.28 001280318.1_39724001_2 - 0.00015 22.0 0.0 0.00032 20.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2_3 PF14378.4 001280318.1_39724001_2 - 0.0025 17.4 16.8 0.013 15.1 16.6 2.0 1 1 0 1 1 1 1 PAP2 superfamily SAM_2 PF07647.15 001280318.1_39724001_2 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.14 001280318.1_39724001_2 - 0.023 14.5 0.2 0.11 12.4 0.2 2.2 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain UPF0220 PF05255.9 001280318.1_39724001_2 - 0.034 13.6 0.8 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) Ctr PF04145.13 001302425.1_39724001_1 - 2.1e-28 99.7 2.9 3.1e-28 99.1 2.9 1.3 1 0 0 1 1 1 1 Ctr copper transporter family SRP9-21 PF05486.10 001246578.1_39723001_3 - 6.6e-11 42.3 0.2 4.6e-10 39.6 0.2 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Cullin PF00888.20 001246604.1_39727001_2 - 4.5e-200 666.2 19.8 4.5e-200 666.2 19.8 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.7 001246604.1_39727001_2 - 4e-28 97.1 2.9 1.5e-27 95.3 1.9 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Memo PF01875.15 001280096.1_39724001_1 - 2.8e-79 266.0 0.0 3.4e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Gal-3-0_sulfotr PF06990.9 001246363.1_39724001_3 - 8.8e-206 683.3 0.1 1.1e-205 683.1 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Pescadillo_N PF06732.9 001246365.1_39725001_2 - 2.3e-130 434.0 3.4 2.3e-130 434.0 3.4 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.3 001246365.1_39725001_2 - 4.6e-10 39.6 0.0 9e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.24 001246365.1_39725001_2 - 0.0023 18.1 0.0 0.0068 16.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4648 PF15505.4 001251906.1_39722001_1 - 4.1e-83 277.8 0.3 5.4e-83 277.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4648) Pro_isomerase PF00160.19 001280367.1_39724001_1 - 1e-32 113.4 0.4 1.6e-32 112.8 0.4 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SpoU_methylase PF00588.17 001279817.1_39724001_3 - 3.3e-21 75.8 0.0 7.5e-20 71.4 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.10 001279817.1_39724001_3 - 0.0038 17.3 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Fz PF01392.20 001280534.1_39725001_2 - 4.6e-28 98.0 3.0 1e-27 96.9 3.0 1.6 1 0 0 1 1 1 1 Fz domain NTR PF01759.19 001280534.1_39725001_2 - 9.3e-14 51.0 1.2 1.5e-13 50.4 1.2 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module DUF3797 PF12677.5 001246551.2_39725001_1 - 0.042 13.6 0.3 0.042 13.6 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) BORG_CEP PF14957.4 001246551.2_39725001_3 - 1.1e-33 116.7 3.1 1.8e-33 116.1 3.1 1.3 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.26 001246551.2_39725001_3 - 9e-09 35.5 0.2 1.5e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain DMRT-like PF15791.3 001246532.1_39724001_2 - 1.6e-51 173.6 8.6 1.6e-51 173.6 8.6 1.9 2 0 0 2 2 2 1 Doublesex-and mab-3-related transcription factor C1 and C2 DM PF00751.16 001246532.1_39724001_2 - 3.5e-20 71.5 9.9 3.5e-20 71.5 9.9 1.7 2 0 0 2 2 2 1 DM DNA binding domain AAA_33 PF13671.4 001246526.1_39727001_3 - 7.6e-28 97.3 0.1 1.4e-27 96.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain SPRY PF00622.26 001246526.1_39727001_3 - 7.1e-23 80.9 0.2 1.4e-22 79.9 0.2 1.5 1 0 0 1 1 1 1 SPRY domain SAP PF02037.25 001246526.1_39727001_3 - 5.1e-10 38.7 2.9 1.1e-09 37.7 2.9 1.6 1 0 0 1 1 1 1 SAP domain AAA_18 PF13238.4 001246526.1_39727001_3 - 0.045 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain LIM PF00412.20 001246623.2_39724001_2 - 1.3e-31 108.4 21.6 4.4e-13 49.1 1.4 3.3 3 0 0 3 3 3 3 LIM domain SR-25 PF10500.7 001246623.2_39724001_3 - 0.2 11.1 18.7 0.29 10.6 18.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_M19 PF01244.19 001246484.1_39724001_3 - 2.1e-110 368.7 0.0 2.5e-110 368.4 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) zf-H2C2_2 PF13465.4 001280308.1_39725001_3 - 5.3e-120 386.9 145.9 8.2e-10 38.5 1.0 17.4 17 0 0 17 17 17 16 Zinc-finger double domain zf-C2H2 PF00096.24 001280308.1_39725001_3 - 2.6e-67 219.6 128.9 2.1e-06 27.8 0.9 15.9 15 0 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280308.1_39725001_3 - 3e-53 173.7 124.4 0.00027 21.4 4.4 16.0 16 0 0 16 16 15 15 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001280308.1_39725001_3 - 1.3e-31 107.8 104.2 0.00011 21.9 0.2 15.8 15 1 0 15 15 15 12 C2H2-type zinc finger KRAB PF01352.25 001280308.1_39725001_3 - 4.4e-24 83.8 0.7 7.7e-24 83.0 0.7 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 001280308.1_39725001_3 - 7.5e-22 77.0 62.6 0.039 14.1 0.1 14.1 12 1 1 13 13 13 11 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.3 001280308.1_39725001_3 - 1.4e-20 72.5 86.5 0.0011 18.5 2.6 15.0 15 0 0 15 15 15 9 zinc-finger C2H2-type zf-trcl PF13451.4 001280308.1_39725001_3 - 3.5e-12 45.9 56.6 0.93 9.3 3.3 13.7 12 2 2 14 14 14 6 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.8 001280308.1_39725001_3 - 1.6e-10 40.8 92.5 0.0044 17.0 1.5 12.2 5 3 10 15 15 14 12 Zinc ribbon domain zinc_ribbon_15 PF17032.3 001280308.1_39725001_3 - 1.2e-05 25.8 65.3 0.15 12.7 1.7 8.1 1 1 6 9 9 9 5 zinc-ribbon family DUF3741 PF12552.6 001280308.1_39725001_3 - 0.012 15.4 0.9 73 3.3 0.0 5.6 7 0 0 7 7 7 0 Protein of unknown function (DUF3741) zf-BED PF02892.13 001280308.1_39725001_3 - 0.025 14.5 96.3 0.28 11.1 4.4 14.2 1 1 11 13 13 13 0 BED zinc finger AAA_14 PF13173.4 001280308.1_39725001_3 - 0.025 14.5 0.7 42 4.0 0.0 4.7 4 1 1 5 5 5 0 AAA domain zf-met PF12874.5 001280308.1_39725001_3 - 0.11 12.8 0.3 0.11 12.8 0.3 13.9 14 0 0 14 14 14 0 Zinc-finger of C2H2 type XPA_N PF01286.16 001280308.1_39725001_3 - 0.43 10.5 70.1 4.2 7.4 0.3 14.6 15 0 0 15 15 15 0 XPA protein N-terminal FYVE PF01363.19 001280308.1_39725001_3 - 0.47 10.5 86.8 3.2 7.8 6.0 10.3 1 1 5 6 6 5 0 FYVE zinc finger Raffinose_syn PF05691.10 001280308.1_39725001_3 - 0.67 7.5 4.6 5.3 4.6 0.2 3.3 2 1 1 3 3 3 0 Raffinose synthase or seed imbibition protein Sip1 zf-H2C2_2 PF13465.4 001328170.1_39729001_2 - 1e-59 196.3 67.8 1.5e-08 34.5 0.2 12.3 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2 PF00096.24 001328170.1_39729001_2 - 1.5e-40 135.3 75.5 1.2e-06 28.5 0.3 11.5 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001328170.1_39729001_2 - 6.6e-23 79.3 70.2 0.00098 19.6 1.1 11.7 11 0 0 11 11 11 9 C2H2-type zinc finger KRAB PF01352.25 001328170.1_39729001_2 - 1.4e-21 75.7 2.3 2.6e-21 74.9 2.3 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 001328170.1_39729001_2 - 5.3e-09 36.0 38.6 0.95 9.7 0.0 9.6 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001328170.1_39729001_2 - 5e-07 29.4 52.4 0.01 15.6 2.5 9.8 10 0 0 10 10 10 7 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001328170.1_39729001_2 - 2.5e-05 24.2 41.0 0.017 15.1 2.5 6.8 4 2 4 8 8 7 5 Zinc ribbon domain DZR PF12773.5 001328170.1_39729001_2 - 0.0028 17.5 34.5 0.74 9.7 0.1 5.6 2 1 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.3 001328170.1_39729001_2 - 0.036 14.7 29.4 1.7 9.3 0.8 6.1 3 1 5 8 8 8 0 zinc-ribbon family Siva PF05458.10 001328170.1_39729001_2 - 6.7 6.2 17.1 3.6 7.1 0.3 3.6 1 1 2 3 3 3 0 Cd27 binding protein (Siva) Metallothio PF00131.18 001252594.1_39721001_1 - 1.4e-19 69.8 64.7 1.9e-19 69.4 64.7 1.2 1 0 0 1 1 1 1 Metallothionein His_Phos_1 PF00300.20 001246485.1_39724001_2 - 3.4e-34 118.1 0.1 2.1e-26 92.7 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) CDKN3 PF05706.10 001280242.1_39722001_2 - 1.5e-116 385.7 1.3 1.8e-116 385.4 1.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.25 001280242.1_39722001_2 - 8e-05 22.2 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.18 001280242.1_39722001_2 - 0.00018 21.2 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LBP_BPI_CETP PF01273.23 001243278.2_39723001_3 - 1.1e-22 80.3 0.1 1.6e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain zf-H2C2_2 PF13465.4 001280159.1_39724001_2 - 1.2e-91 297.3 103.7 8.8e-09 35.3 2.1 13.2 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.24 001280159.1_39724001_2 - 1.3e-47 157.5 97.8 2.3e-05 24.4 1.1 12.7 13 0 0 13 13 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280159.1_39724001_2 - 1.1e-30 103.5 84.5 0.0014 19.2 0.8 12.6 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001280159.1_39724001_2 - 4.5e-30 102.9 93.3 0.00038 20.2 0.5 13.1 13 0 0 13 13 12 11 C2H2-type zinc finger KRAB PF01352.25 001280159.1_39724001_2 - 1.5e-25 88.5 0.9 2.7e-25 87.6 0.9 1.5 1 0 0 1 1 1 1 KRAB box Zn-ribbon_8 PF09723.8 001280159.1_39724001_2 - 3.5e-16 58.9 63.8 0.00072 19.5 0.9 8.0 6 4 2 8 8 8 6 Zinc ribbon domain zf-C2H2_jaz PF12171.6 001280159.1_39724001_2 - 8.6e-12 44.9 61.7 0.13 12.4 1.0 12.2 12 0 0 12 12 12 5 Zinc-finger double-stranded RNA-binding XPA_N PF01286.16 001280159.1_39724001_2 - 6.3e-05 22.8 58.2 2.4 8.1 0.0 12.1 12 0 0 12 12 12 3 XPA protein N-terminal zf-trcl PF13451.4 001280159.1_39724001_2 - 0.00099 18.8 63.2 1.9 8.3 0.1 12.0 11 2 0 11 11 10 4 Probable zinc-ribbon domain C1_4 PF07975.10 001280159.1_39724001_2 - 0.0017 18.4 53.0 0.32 11.2 1.6 8.0 2 2 7 9 9 9 6 TFIIH C1-like domain zinc_ribbon_15 PF17032.3 001280159.1_39724001_2 - 0.0037 17.9 54.5 0.17 12.5 1.0 6.7 1 1 7 9 9 9 5 zinc-ribbon family zf-LYAR PF08790.9 001280159.1_39724001_2 - 0.041 13.6 51.3 1.2 9.0 0.1 11.0 12 0 0 12 12 12 0 LYAR-type C2HC zinc finger Zn_Tnp_IS1595 PF12760.5 001280159.1_39724001_2 - 5.1 7.0 73.9 1.1 9.2 4.7 9.8 5 3 3 8 8 7 0 Transposase zinc-ribbon domain zf-C2H2_11 PF16622.3 001280159.1_39724001_2 - 7.2 6.3 55.1 0.99 9.1 0.3 11.2 12 0 0 12 12 12 0 zinc-finger C2H2-type TFIIE_alpha PF02002.15 001243861.1_39727001_1 - 4.8e-36 122.7 0.8 7.9e-36 122.0 0.8 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.6 001243861.1_39727001_1 - 1.1e-31 108.8 6.6 2.1e-31 108.0 6.6 1.5 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.10 001243861.1_39727001_1 - 3.3e-13 48.8 0.7 5.8e-13 48.0 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding LRR_8 PF13855.4 001130470.1_39726001_1 - 4.8e-79 259.9 96.1 7.9e-12 44.6 3.3 11.1 7 4 3 11 11 11 11 Leucine rich repeat LRR_4 PF12799.5 001130470.1_39726001_1 - 3.8e-34 115.9 99.1 1.9e-05 24.8 5.9 13.8 6 3 8 15 15 15 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.4 001130470.1_39726001_1 - 6.2e-22 77.8 29.1 1.3e-06 28.3 6.6 6.2 2 1 3 6 6 6 5 Leucine rich repeats (6 copies) LRR_9 PF14580.4 001130470.1_39726001_1 - 7.9e-13 48.1 36.2 5.4e-06 25.9 1.9 7.7 2 1 7 9 9 9 6 Leucine-rich repeat LRR_1 PF00560.31 001130470.1_39726001_1 - 2.8e-11 42.1 84.1 1.5 9.4 0.1 20.8 21 1 0 21 21 21 6 Leucine Rich Repeat LRR_6 PF13516.4 001130470.1_39726001_1 - 8e-09 34.7 87.0 0.33 11.0 0.1 18.9 19 0 0 19 19 19 7 Leucine Rich repeat TIR PF01582.18 001130470.1_39726001_1 - 1e-08 35.0 0.8 1.9e-08 34.2 0.8 1.4 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.16 001130470.1_39726001_1 - 0.0016 17.9 0.3 0.0052 16.3 0.3 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRRCT PF01463.22 001130470.1_39726001_1 - 0.0069 16.7 0.1 0.048 14.1 0.1 2.6 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain TIR_2 PF13676.4 001130470.1_39726001_1 - 0.078 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 TIR domain Filament PF00038.19 001098552.1_39724001_3 - 7.9e-105 350.7 35.2 9.4e-105 350.5 35.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Uso1_p115_C PF04871.11 001098552.1_39724001_3 - 0.0029 17.8 21.1 0.09 13.0 6.6 2.9 2 2 1 3 3 3 2 Uso1 / p115 like vesicle tethering protein, C terminal region Phage_GP20 PF06810.9 001098552.1_39724001_3 - 0.0082 15.8 17.6 0.057 13.1 3.8 2.8 2 2 0 2 2 2 2 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.10 001098552.1_39724001_3 - 0.02 14.8 30.9 0.19 11.7 11.8 3.8 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.7 001098552.1_39724001_3 - 0.13 11.2 22.8 1.4 7.8 12.3 3.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.10 001098552.1_39724001_3 - 0.16 11.9 17.4 0.036 14.0 8.0 3.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_C PF07195.10 001098552.1_39724001_3 - 0.35 10.1 6.5 0.25 10.6 3.4 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF1664 PF07889.10 001098552.1_39724001_3 - 0.66 9.8 18.1 2.3 8.1 0.6 4.3 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Prefoldin PF02996.15 001098552.1_39724001_3 - 0.67 9.7 21.6 0.93 9.3 1.0 4.9 4 2 2 6 6 6 0 Prefoldin subunit Spore_GerAC PF05504.9 001098552.1_39724001_3 - 1 9.5 5.0 4.1 7.6 3.1 2.7 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal Reo_sigmaC PF04582.10 001098552.1_39724001_3 - 1.9 7.7 10.6 0.6 9.3 3.4 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF342 PF03961.11 001098552.1_39724001_3 - 2 6.8 12.8 0.17 10.4 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Bacillus_HBL PF05791.9 001098552.1_39724001_3 - 2.2 7.9 14.2 0.082 12.5 5.4 2.7 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.6 001098552.1_39724001_3 - 3.2 7.7 30.5 3.2 7.7 13.5 3.5 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding DivIC PF04977.13 001098552.1_39724001_3 - 3.2 7.5 28.0 7.4 6.3 0.9 5.2 3 1 2 5 5 5 0 Septum formation initiator SKA1 PF07160.10 001098552.1_39724001_3 - 3.2 7.4 19.0 0.047 13.4 7.4 2.8 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 NYD-SP28_assoc PF14775.4 001098552.1_39724001_3 - 4.4 7.3 13.4 0.85 9.6 0.9 3.9 4 0 0 4 4 4 0 Sperm tail C-terminal domain HXXSHH PF07586.9 001098552.1_39724001_3 - 4.8 6.5 6.7 1.9 7.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) TMPIT PF07851.11 001098552.1_39724001_3 - 5.9 5.9 10.7 0.48 9.5 2.7 2.2 2 0 0 2 2 2 0 TMPIT-like protein Spc7 PF08317.9 001098552.1_39724001_3 - 9.2 4.9 29.8 4.8 5.8 12.2 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein Lzipper-MIP1 PF14389.4 001098552.1_39724001_3 - 9.4 6.4 22.0 0.025 14.7 4.8 4.6 4 2 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 SOSSC PF15925.3 001242593.1_39727001_1 - 1.1e-20 74.7 0.4 2.7e-20 73.4 0.4 1.7 1 1 0 1 1 1 1 SOSS complex subunit C Sulfatase PF00884.21 001280396.1_39724001_3 - 1.2e-80 271.1 0.0 1.6e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.4 001280396.1_39724001_3 - 2.3e-26 92.8 0.0 3.8e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.20 001280396.1_39724001_3 - 2.6e-05 23.8 0.1 0.0041 16.6 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.10 001280396.1_39724001_3 - 0.012 14.6 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4976 PF16347.3 001280396.1_39724001_3 - 0.016 15.3 0.0 5.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Ribosomal_L18A PF01775.15 001252032.1_39722001_1 - 2e-56 189.2 0.0 2.6e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A FUN14 PF04930.13 001251911.1_39722001_1 - 1.6e-27 95.6 3.4 2.4e-27 95.0 3.4 1.3 1 0 0 1 1 1 1 FUN14 family Pkinase PF00069.23 001279947.1_39725001_1 - 7.1e-41 140.2 6.9 6.9e-22 77.9 0.2 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.15 001279947.1_39725001_1 - 1.6e-12 47.1 0.1 6.9e-09 35.2 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HNOB PF07700.13 001279947.1_39725001_1 - 0.041 13.7 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Haem-NO-binding EF-hand_7 PF13499.4 001246377.1_39724001_1 - 3.9e-27 94.4 3.7 4.1e-17 62.3 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.30 001246377.1_39724001_1 - 6e-25 84.8 4.8 1.4e-06 27.3 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.4 001246377.1_39724001_1 - 1.3e-21 74.5 2.9 2.7e-06 26.8 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.4 001246377.1_39724001_1 - 1.3e-20 71.8 2.6 1.2e-06 27.6 0.3 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.4 001246377.1_39724001_1 - 1.2e-18 66.5 1.4 2.1e-07 30.5 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001246377.1_39724001_1 - 2.4e-05 24.5 0.3 0.013 15.7 0.1 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001246377.1_39724001_1 - 0.00031 20.5 0.5 0.89 9.4 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.4 001246377.1_39724001_1 - 0.063 13.0 0.1 18 5.2 0.1 2.7 2 0 0 2 2 2 0 EF hand AAA_33 PF13671.4 001280278.1_39727001_2 - 1e-28 100.1 0.1 1.8e-28 99.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain SPRY PF00622.26 001280278.1_39727001_2 - 1.1e-13 51.2 0.1 1.1e-13 51.2 0.1 1.8 2 0 0 2 2 2 1 SPRY domain SAP PF02037.25 001280278.1_39727001_2 - 3e-10 39.5 6.0 5.5e-10 38.6 6.0 1.5 1 0 0 1 1 1 1 SAP domain Zeta_toxin PF06414.10 001280278.1_39727001_2 - 0.046 12.9 0.1 0.088 12.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.20 001280278.1_39727001_2 - 0.049 13.1 0.2 0.079 12.4 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.4 001280278.1_39727001_2 - 0.061 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Kazal_2 PF07648.13 001244588.2_39729001_1 - 3.5e-12 46.2 4.9 9e-12 44.9 4.9 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain FOLN PF09289.8 001244588.2_39729001_1 - 3e-06 27.1 1.9 8.3e-06 25.7 1.9 1.8 1 0 0 1 1 1 1 Follistatin/Osteonectin-like EGF domain Kazal_1 PF00050.19 001244588.2_39729001_1 - 1.6e-05 24.7 9.6 4.4e-05 23.3 9.6 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Pacifastin_I PF05375.11 001244588.2_39729001_1 - 0.00082 18.9 11.1 0.0029 17.2 11.1 2.0 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) EF-hand_6 PF13405.4 001244588.2_39729001_1 - 0.018 14.8 0.2 5.1 7.2 0.3 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.4 001244588.2_39729001_1 - 0.033 14.5 0.8 0.066 13.6 0.8 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.30 001244588.2_39729001_1 - 0.22 11.0 1.6 11 5.7 0.8 2.4 2 0 0 2 2 2 0 EF hand PBP_sp32 PF07222.10 001246605.1_39724001_1 - 4.3e-136 451.9 5.7 4.3e-136 451.9 5.7 1.9 2 0 0 2 2 2 1 Proacrosin binding protein sp32 Kazal_2 PF07648.13 001246605.1_39724001_1 - 0.005 16.9 0.9 0.005 16.9 0.9 3.2 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.19 001246605.1_39724001_1 - 0.073 13.0 0.3 0.073 13.0 0.3 2.8 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DDHD PF02862.15 001246605.1_39724001_1 - 0.11 12.5 3.4 0.17 11.8 3.4 1.3 1 0 0 1 1 1 0 DDHD domain TFIIF_alpha PF05793.10 001246605.1_39724001_1 - 0.18 10.2 14.3 0.25 9.7 14.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Plasmodium_Vir PF05795.9 001246605.1_39724001_1 - 0.31 10.3 8.0 0.47 9.7 8.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein WRNPLPNID PF15017.4 001246605.1_39724001_1 - 5.1 7.9 10.7 1e+02 3.8 9.1 2.7 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Orn_Arg_deC_N PF02784.14 001301719.1_39726001_3 - 6.2e-64 215.7 0.1 7.8e-64 215.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001301719.1_39726001_3 - 1.4e-24 86.2 0.0 2.6e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-H2C2_2 PF13465.4 001251856.2_39724001_2 - 5.5e-77 250.9 105.4 7.5e-09 35.5 1.4 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.24 001251856.2_39724001_2 - 6.9e-48 158.4 93.6 7.9e-06 25.9 1.3 12.7 12 0 0 12 12 12 11 Zinc finger, C2H2 type KRAB PF01352.25 001251856.2_39724001_2 - 6.2e-26 89.7 0.1 1.5e-25 88.4 0.1 1.7 1 0 0 1 1 1 1 KRAB box zf-C2H2_4 PF13894.4 001251856.2_39724001_2 - 2.8e-25 86.7 86.0 0.0065 17.1 0.8 12.7 12 0 0 12 12 12 9 C2H2-type zinc finger zf-C2H2_6 PF13912.4 001251856.2_39724001_2 - 3.7e-20 71.3 78.9 0.00017 21.3 0.2 12.4 12 0 0 12 12 12 8 C2H2-type zinc finger XPA_N PF01286.16 001251856.2_39724001_2 - 1.9e-15 56.5 56.6 0.22 11.5 0.0 12.2 12 0 0 12 12 12 9 XPA protein N-terminal zf-C2H2_jaz PF12171.6 001251856.2_39724001_2 - 1.2e-11 44.4 62.4 0.068 13.4 0.2 11.9 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.8 001251856.2_39724001_2 - 3.2e-10 39.8 69.2 0.023 14.7 5.2 9.4 7 5 3 10 10 9 7 Zinc ribbon domain zf-RING_7 PF02591.13 001251856.2_39724001_2 - 3.9e-08 33.2 35.4 0.33 11.1 0.0 10.1 10 0 0 10 10 10 3 C4-type zinc ribbon domain zf-trcl PF13451.4 001251856.2_39724001_2 - 0.0011 18.6 59.8 1.8 8.4 0.1 10.8 7 4 0 7 7 7 3 Probable zinc-ribbon domain zf-C2H2_11 PF16622.3 001251856.2_39724001_2 - 0.0084 15.7 38.1 1.4 8.6 0.0 10.6 11 0 0 11 11 11 2 zinc-finger C2H2-type zinc_ribbon_15 PF17032.3 001251856.2_39724001_2 - 0.013 16.1 58.0 0.4 11.3 2.6 6.7 1 1 3 6 6 6 0 zinc-ribbon family MRP-S23 PF10484.7 001251856.2_39724001_2 - 0.017 15.2 3.5 57 3.8 0.0 5.7 2 1 4 6 6 6 0 Mitochondrial ribosomal protein S23 ADK_lid PF05191.12 001251856.2_39724001_2 - 0.65 9.9 45.2 0.49 10.3 1.5 7.5 7 1 0 7 7 7 0 Adenylate kinase, active site lid GAGA PF09237.9 001251856.2_39724001_2 - 0.94 9.2 19.8 0.28 10.9 0.2 5.3 4 2 3 7 7 7 0 GAGA factor zf-AN1 PF01428.14 001251856.2_39724001_2 - 2.9 8.0 61.2 14 5.9 0.4 11.8 9 3 3 12 12 12 0 AN1-like Zinc finger PDDEXK_10 PF07788.9 001251856.2_39724001_3 - 0.013 15.3 0.1 1e+02 2.8 0.0 5.2 7 0 0 7 7 7 0 PD-(D/E)XK nuclease superfamily Ubiq_cyt_C_chap PF03981.10 001280459.1_39725001_2 - 9.4e-39 132.6 0.0 1.3e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Dynamitin PF04912.12 001280048.1_39724001_1 - 1.3e-125 419.6 17.2 1.5e-125 419.4 17.2 1.0 1 0 0 1 1 1 1 Dynamitin ALIX_LYPXL_bnd PF13949.4 001280048.1_39724001_1 - 0.002 17.4 13.3 0.13 11.4 0.4 2.3 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV ZapB PF06005.10 001280048.1_39724001_1 - 1.4 9.3 22.3 0.25 11.7 6.2 4.3 3 2 0 3 3 3 0 Cell division protein ZapB FlaC_arch PF05377.9 001280048.1_39724001_1 - 2.2 8.6 9.7 14 6.1 0.5 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) CorA PF01544.16 001280048.1_39724001_1 - 2.4 7.2 9.2 12 4.9 0.2 2.7 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein 5_3_exonuc PF01367.18 001280048.1_39724001_1 - 4.2 7.9 9.4 3.8 8.0 0.9 3.5 3 1 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Aldedh PF00171.20 001246547.1_39725001_2 - 1.3e-184 613.9 0.0 1.5e-184 613.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.12 001246547.1_39725001_2 - 0.0013 17.8 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) RNase_H PF00075.22 001286017.1_39724001_3 - 4.5e-44 150.0 0.0 7.1e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.14 001286017.1_39724001_3 - 4.6e-19 68.3 0.9 1.1e-18 67.1 0.9 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.4 001286017.1_39724001_3 - 0.0092 15.5 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like GDP_Man_Dehyd PF16363.3 001280393.1_39725001_2 - 2.7e-55 187.9 0.0 9e-55 186.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.19 001280393.1_39725001_2 - 9.4e-50 169.2 0.0 1.3e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UXS1_N PF11803.6 001280393.1_39725001_2 - 3.4e-36 123.3 0.1 6.5e-36 122.4 0.1 1.5 1 0 0 1 1 1 1 UDP-glucuronate decarboxylase N-terminal NAD_binding_4 PF07993.10 001280393.1_39725001_2 - 1.5e-09 37.3 0.0 8.2e-06 25.0 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.15 001280393.1_39725001_2 - 2e-09 36.8 0.0 2.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.17 001280393.1_39725001_2 - 1.5e-07 30.5 0.0 3.2e-07 29.5 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.13 001280393.1_39725001_2 - 3.3e-07 29.6 0.2 0.00047 19.2 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Pkinase PF00069.23 001329736.1_39728001_1 - 3.8e-35 121.4 0.0 5.5e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001329736.1_39728001_1 - 5.1e-18 65.1 0.0 7.2e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001329736.1_39728001_1 - 3.9e-05 23.0 0.1 0.00016 21.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.12 001329736.1_39728001_1 - 0.12 11.5 0.2 0.2 10.9 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Shisa PF13908.4 001246427.1_39725001_1 - 3.1e-42 144.9 11.6 7.2e-42 143.6 11.6 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator 7tm_1 PF00001.19 001280182.1_39725001_1 - 4.3e-37 127.7 28.5 1.5e-36 125.9 28.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ribosomal_S27e PF01667.15 001251997.1_39721001_2 - 2.8e-30 103.7 5.1 3.6e-30 103.3 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Ras PF00071.20 001280271.1_39724001_1 - 2.6e-22 79.0 0.0 3.6e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Pox_A_type_inc PF04508.10 001280345.1_39726001_2 - 0.046 13.5 0.6 0.046 13.5 0.6 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat CT_C_D PF02682.14 001280345.1_39726001_2 - 0.31 10.6 3.4 0.22 11.1 1.0 1.9 1 1 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D DUF2911 PF11138.6 001280345.1_39726001_2 - 1.1 9.0 4.7 0.56 9.9 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2911) Alanine_zipper PF11839.6 001280345.1_39726001_2 - 1.4 9.1 8.9 1 9.5 1.1 3.6 3 1 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein zf-C2HC_2 PF13913.4 001246584.1_39725001_1 - 4.1e-10 39.2 12.9 3.3e-06 26.7 2.4 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-LITAF-like PF10601.7 001243097.1_39726001_3 - 1.2e-21 76.6 13.9 1.2e-21 76.6 13.9 2.7 3 0 0 3 3 3 1 LITAF-like zinc ribbon domain Calponin PF00402.16 001280279.1_39724001_1 - 5.8e-43 144.0 22.3 2e-16 59.2 1.8 3.8 4 0 0 4 4 4 3 Calponin family repeat CH PF00307.29 001280279.1_39724001_1 - 1.1e-22 80.2 0.1 1.6e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain FWWh PF14922.4 001246614.1_39725001_3 - 2.1e-54 183.4 0.3 4.3e-54 182.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function DegS PF05384.9 001246614.1_39725001_3 - 0.013 14.9 0.1 0.032 13.6 0.1 1.7 1 0 0 1 1 1 0 Sensor protein DegS DUF4897 PF16238.3 001246614.1_39725001_3 - 0.081 12.6 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) SH3_1 PF00018.26 001280240.2_39724001_3 - 1.6e-12 46.7 0.0 1.5e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.4 001280240.2_39724001_3 - 3.4e-12 45.9 0.1 1.4e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.15 001280240.2_39724001_3 - 6.1e-06 25.7 0.0 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.22 001280240.2_39724001_3 - 8.6e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 PX domain p47_phox_C PF08944.9 001280240.2_39724001_3 - 0.012 14.9 5.9 0.068 12.5 5.9 2.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain SH3_3 PF08239.9 001280240.2_39724001_3 - 0.052 13.7 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain DUF727 PF05303.10 001242570.1_39725001_1 - 9.9e-32 109.0 0.0 1.5e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF727) VKOR PF07884.12 001251930.1_39722001_2 - 7.7e-26 90.6 12.8 1e-25 90.2 12.8 1.2 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Copper-fist PF00649.16 001251930.1_39722001_2 - 0.19 11.1 1.0 0.36 10.2 0.2 1.8 2 0 0 2 2 2 0 Copper fist DNA binding domain ANF_receptor PF01094.26 001164701.1_39728001_1 - 2.2e-93 313.1 0.0 3.3e-93 312.5 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.20 001164701.1_39728001_1 - 1.5e-56 191.7 27.9 2.2e-56 191.2 27.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR GluR_Homer-bdg PF10606.7 001164701.1_39728001_1 - 3.2e-25 87.9 10.5 1.1e-24 86.2 10.5 2.0 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.12 001164701.1_39728001_1 - 5.1e-15 55.1 10.7 1e-14 54.1 10.7 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF2318 PF10080.7 001164701.1_39728001_1 - 0.044 13.8 3.1 0.11 12.4 3.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) AAA_34 PF13872.4 001164701.1_39728001_1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 MAGE_N PF12440.6 001164701.1_39728001_3 - 0.67 10.5 4.7 2.2 8.9 4.7 1.8 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal TPH PF13868.4 001246479.1_39724001_2 - 4.4e-84 281.9 146.5 4.4e-84 281.9 146.5 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Dak1 PF02733.15 001246594.1_39724001_3 - 3.8e-109 364.2 6.8 5.7e-109 363.6 6.8 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.15 001246594.1_39724001_3 - 3.4e-51 173.5 4.0 7e-51 172.4 4.0 1.6 1 0 0 1 1 1 1 DAK2 domain Kinetochor_Ybp2 PF08568.8 001246440.2_39725001_1 - 5.6e-107 358.6 16.7 6.5e-107 358.4 16.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Tubulin PF00091.23 001280297.1_39724001_2 - 1e-64 218.2 0.0 1.7e-64 217.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001280297.1_39724001_2 - 6.6e-47 158.7 0.1 1.2e-46 157.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001280297.1_39724001_2 - 0.00044 20.4 0.0 0.0013 18.8 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.4 001280297.1_39724001_2 - 0.039 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.4 001280297.1_39724001_2 - 0.065 12.8 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Adap_comp_sub PF00928.19 001280346.1_39724001_1 - 2.5e-80 269.5 0.1 3.2e-80 269.2 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.18 001280346.1_39724001_1 - 1.5e-05 24.9 0.4 2.3e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.7 001280346.1_39724001_1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Pkinase PF00069.23 001280506.1_39724001_2 - 8.2e-54 182.6 0.0 1.2e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280506.1_39724001_2 - 6.3e-19 68.1 0.2 1e-18 67.4 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001280506.1_39724001_2 - 0.0037 17.1 0.0 0.03 14.1 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.4 001280506.1_39724001_2 - 0.015 14.5 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.18 001280506.1_39724001_2 - 0.04 13.4 0.9 0.078 12.4 0.9 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Transmemb_17 PF09799.7 001242568.1_39723001_1 - 1.6e-32 112.2 14.5 3e-32 111.3 14.5 1.5 1 0 0 1 1 1 1 Predicted membrane protein TIP49 PF06068.11 001246529.1_39724001_2 - 8.8e-196 650.4 0.8 1e-195 650.2 0.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.10 001246529.1_39724001_2 - 5e-14 52.0 1.7 1.3e-08 34.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.27 001246529.1_39724001_2 - 2.1e-12 47.5 0.3 3.7e-08 33.7 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.4 001246529.1_39724001_2 - 1.9e-06 28.1 0.1 0.083 13.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.4 001246529.1_39724001_2 - 2.7e-05 24.5 0.0 0.00026 21.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.12 001246529.1_39724001_2 - 9e-05 22.4 0.1 0.0052 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.4 001246529.1_39724001_2 - 0.00021 20.8 0.0 0.0011 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.24 001246529.1_39724001_2 - 0.00037 20.1 0.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.19 001246529.1_39724001_2 - 0.0011 18.3 0.2 0.045 13.0 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.15 001246529.1_39724001_2 - 0.002 17.8 0.1 0.0042 16.7 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.4 001246529.1_39724001_2 - 0.002 18.3 1.7 0.054 13.7 1.7 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.4 001246529.1_39724001_2 - 0.002 18.5 0.0 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.13 001246529.1_39724001_2 - 0.0032 16.7 0.0 0.0069 15.6 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_28 PF13521.4 001246529.1_39724001_2 - 0.0037 17.4 0.1 0.0068 16.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.10 001246529.1_39724001_2 - 0.014 14.6 0.2 0.033 13.3 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.10 001246529.1_39724001_2 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.4 001246529.1_39724001_2 - 0.016 15.2 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.14 001246529.1_39724001_2 - 0.017 14.4 0.1 0.044 13.1 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.13 001246529.1_39724001_2 - 0.018 14.9 0.0 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.15 001246529.1_39724001_2 - 0.02 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.4 001246529.1_39724001_2 - 0.021 14.4 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.15 001246529.1_39724001_2 - 0.025 13.5 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.4 001246529.1_39724001_2 - 0.038 13.6 0.2 1 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.7 001246529.1_39724001_2 - 0.091 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.11 001246529.1_39724001_2 - 0.11 11.7 2.2 0.26 10.5 0.0 2.4 3 0 0 3 3 3 0 KaiC Asp_protease_2 PF13650.4 001172427.3_39729001_2 - 0.00076 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.9 001172427.3_39729001_2 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.4 001172427.3_39729001_2 - 0.052 14.0 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.3 001172427.3_39729001_3 - 5.4e-15 55.1 0.0 9.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.15 001172427.3_39729001_3 - 1.2e-14 54.2 1.9 5e-14 52.2 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Rootletin PF15035.4 001172427.3_39729001_3 - 0.00043 20.3 0.1 0.00081 19.4 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.4 001172427.3_39729001_3 - 0.002 17.9 4.7 0.0032 17.2 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-CCHC_5 PF14787.4 001172427.3_39729001_3 - 0.0028 17.2 0.2 0.0064 16.0 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Spc29 PF17082.3 001172427.3_39729001_3 - 0.0069 16.1 0.4 0.011 15.4 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 CENP-H PF05837.10 001172427.3_39729001_3 - 0.24 11.7 4.8 0.47 10.8 4.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.10 001172427.3_39729001_3 - 0.33 11.3 9.2 0.67 10.3 9.2 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DUF972 PF06156.11 001172427.3_39729001_3 - 0.33 11.5 3.8 0.79 10.3 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.9 001172427.3_39729001_3 - 0.37 9.5 3.4 0.65 8.7 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.3 001172427.3_39729001_3 - 0.38 11.0 3.9 0.68 10.2 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) LPP PF04728.11 001172427.3_39729001_3 - 0.62 10.4 2.1 1.3 9.4 2.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper SHE3 PF17078.3 001172427.3_39729001_3 - 0.79 9.3 7.3 1.6 8.3 7.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.13 001172427.3_39729001_3 - 1.2 8.8 5.9 2.3 7.9 5.9 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.19 001172427.3_39729001_3 - 1.5 8.8 8.4 3.3 7.8 8.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.12 001172427.3_39729001_3 - 1.7 8.3 5.3 3.3 7.3 5.3 1.4 1 0 0 1 1 1 0 IncA protein TSC22 PF01166.16 001172427.3_39729001_3 - 6.9 6.9 7.5 39 4.5 7.5 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family MIIP PF15734.3 001145656.1_39724001_3 - 4e-155 516.5 8.9 5.2e-155 516.1 8.9 1.1 1 0 0 1 1 1 1 Migration and invasion-inhibitory Tubulin PF00091.23 001279958.1_39724001_1 - 2.2e-69 233.5 0.0 3.3e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001279958.1_39724001_1 - 4e-42 143.3 0.1 6.3e-42 142.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001279958.1_39724001_1 - 3e-06 27.4 0.0 8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001279958.1_39724001_1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.4 001279958.1_39724001_1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like V-set PF07686.15 001280276.1_39725001_3 - 3.4e-16 59.2 1.5 1.6e-07 31.3 0.0 4.2 2 2 1 4 4 4 3 Immunoglobulin V-set domain Ig_3 PF13927.4 001280276.1_39725001_3 - 1.3e-15 57.6 2.6 3.6e-08 33.8 0.1 3.3 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001280276.1_39725001_3 - 1.7e-12 47.1 0.0 4.1e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.23 001280276.1_39725001_3 - 1.1e-11 44.6 3.8 0.00018 21.5 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.4 001280276.1_39725001_3 - 1e-09 38.5 2.1 0.00011 22.3 0.2 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Trypan_PARP PF05887.9 001280276.1_39725001_3 - 0.01 15.8 28.7 0.01 15.8 28.7 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Gly-zipper_Omp PF13488.4 001280276.1_39725001_3 - 0.077 12.9 0.4 0.14 12.1 0.4 1.3 1 0 0 1 1 1 0 Glycine zipper SNF2_N PF00176.21 001271659.1_39728001_3 - 3.7e-79 265.8 0.9 6.4e-79 265.1 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.8 001271659.1_39728001_3 - 1.4e-43 147.4 2.4 4.1e-43 145.9 2.4 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.9 001271659.1_39728001_3 - 3.5e-30 104.9 2.1 3.5e-30 104.9 2.1 3.0 3 0 0 3 3 3 1 HAND Helicase_C PF00271.29 001271659.1_39728001_3 - 3.1e-20 72.5 0.0 1.6e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001271659.1_39728001_3 - 5.7e-11 42.6 0.0 3.6e-10 40.0 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.27 001271659.1_39728001_3 - 4e-06 26.6 0.0 1.7e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.6 001271659.1_39728001_3 - 4.7e-06 25.8 0.0 9e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.29 001271659.1_39728001_3 - 6.7e-05 22.8 0.3 0.34 11.0 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DBINO PF13892.4 001271659.1_39728001_3 - 0.00011 22.4 0.2 0.00011 22.4 0.2 3.5 2 0 0 2 2 2 1 DNA-binding domain ERCC3_RAD25_C PF16203.3 001271659.1_39728001_3 - 0.0014 17.8 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF3699 PF12480.6 001279918.1_39724001_3 - 1e-27 95.9 1.3 1.9e-27 95.0 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3699) Coa1 PF08695.8 001251840.1_39723001_1 - 2.4e-20 72.3 0.0 3.2e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Sina PF03145.14 001246359.1_39725001_3 - 7e-90 300.2 0.1 9.7e-90 299.8 0.1 1.2 1 0 0 1 1 1 1 Seven in absentia protein family PCO_ADO PF07847.10 001289425.1_39725001_2 - 1.9e-65 219.9 0.0 2.5e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO ERM PF00769.17 001280529.1_39725001_1 - 8.8e-70 235.2 39.6 8.8e-70 235.2 39.6 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.8 001280529.1_39725001_1 - 8.9e-28 96.4 0.0 2.4e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.16 001280529.1_39725001_1 - 5.2e-27 94.5 0.2 5.2e-27 94.5 0.2 3.0 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.8 001280529.1_39725001_1 - 7.6e-14 51.3 0.2 3.1e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain MRP-S27 PF10037.7 001246655.1_39724001_2 - 3.3e-12 45.9 4.1 1.8e-11 43.5 4.1 1.9 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.4 001246655.1_39724001_2 - 1.1e-05 25.4 1.5 1.6e-05 24.8 0.2 1.9 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.18 001246655.1_39724001_2 - 0.0015 18.6 0.5 0.0046 17.0 0.1 2.1 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.4 001246655.1_39724001_2 - 0.0034 17.3 0.1 0.011 15.6 0.1 1.9 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_1 PF12854.5 001246655.1_39724001_2 - 0.0077 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 PPR repeat Utp13 PF08625.9 001246655.1_39724001_2 - 0.11 12.2 0.5 0.44 10.3 0.1 2.1 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain DEAD PF00270.27 001246518.2_39724001_1 - 8.5e-44 149.3 0.3 1.3e-43 148.6 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001246518.2_39724001_1 - 1.6e-31 108.8 0.7 2.3e-30 105.1 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.13 001246518.2_39724001_1 - 1.7e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.4 001246518.2_39724001_1 - 0.00012 22.3 0.4 0.00028 21.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.4 001246518.2_39724001_1 - 0.0027 17.3 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.12 001246518.2_39724001_1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.19 001246518.2_39724001_1 - 0.12 11.7 0.2 0.23 10.8 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.12 001246518.2_39724001_1 - 0.13 12.1 0.0 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain PPTA PF01239.20 001280191.1_39724001_1 - 8.9e-48 158.7 19.3 1.1e-11 43.9 0.5 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat CAP_N PF01213.17 001280191.1_39724001_1 - 6 6.1 12.0 14 4.9 12.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.3 001280191.1_39724001_1 - 7 6.6 7.1 15 5.5 7.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Rho_GDI PF02115.15 001246434.1_39724001_2 - 1.3e-80 269.6 0.3 1.7e-80 269.2 0.3 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4249 PF14054.4 001246434.1_39724001_2 - 0.17 11.3 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) SRP19 PF01922.15 001242420.1_39723001_1 - 4e-28 98.1 0.1 5.6e-28 97.6 0.1 1.2 1 0 0 1 1 1 1 SRP19 protein Ras PF00071.20 001246381.1_39725001_2 - 5.4e-54 182.0 0.0 7.1e-54 181.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001246381.1_39725001_2 - 6.8e-22 77.8 0.0 9.8e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001246381.1_39725001_2 - 8.3e-07 28.5 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family UDG PF03167.17 001246523.1_39725001_3 - 1.2e-23 83.6 0.0 2.8e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Motile_Sperm PF00635.24 001280235.1_39724001_3 - 9e-34 115.5 0.3 1.5e-33 114.7 0.3 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.3 001280235.1_39724001_3 - 0.0062 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin bZIP_1 PF00170.19 001280235.1_39724001_3 - 0.036 14.0 1.1 0.08 12.9 1.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.11 001280235.1_39724001_3 - 0.045 14.2 0.1 0.085 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) B56 PF01603.18 001302436.1_39724001_1 - 3.6e-189 628.8 12.8 4.5e-189 628.5 12.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.5 001302436.1_39724001_1 - 0.01 15.7 4.5 1.8 8.4 0.2 3.8 2 1 2 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RHD_DNA_bind PF00554.20 001246630.1_39726001_2 - 3.8e-69 231.8 0.0 5.1e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.3 001246630.1_39726001_2 - 4.9e-37 126.0 0.0 8.6e-37 125.2 0.0 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain Tau95 PF09734.7 001280358.1_39725001_1 - 6.4e-81 272.2 0.0 1e-80 271.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Pox_Ag35 PF03286.12 001280358.1_39725001_1 - 0.24 11.0 2.7 0.46 10.1 2.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein LAT PF15234.4 001280358.1_39725001_1 - 0.54 9.8 4.1 1.2 8.7 4.1 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells Glyco_transf_11 PF01531.14 001009121.1_39723001_1 - 3.6e-138 459.6 0.0 4.1e-138 459.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.7 001009121.1_39723001_1 - 0.00056 19.5 0.9 0.081 12.5 0.1 2.2 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase DEAD PF00270.27 001280045.1_39725001_2 - 1e-49 168.6 0.0 2.3e-49 167.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001280045.1_39725001_2 - 1e-30 106.2 0.4 5.3e-30 103.9 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001280045.1_39725001_2 - 0.00079 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M24 PF00557.22 001280056.1_39724001_1 - 3e-45 154.3 0.0 4.3e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Sec62 PF03839.14 001280056.1_39724001_1 - 3.7 6.9 7.9 7.1 5.9 7.9 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 NAD_binding_2 PF03446.13 001280248.1_39725001_2 - 0.0032 17.5 0.2 0.0046 17.0 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.17 001280248.1_39725001_3 - 1e-129 431.9 0.0 1.2e-129 431.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.13 001280248.1_39725001_3 - 1.5e-34 119.3 0.0 2.2e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.4 001280248.1_39725001_3 - 0.08 13.1 0.1 0.19 11.8 0.1 1.6 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Aa_trans PF01490.16 001280527.1_39725001_2 - 7e-54 183.0 22.7 8.8e-54 182.6 22.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.11 001280527.1_39725001_2 - 1.4e-08 34.1 22.2 2.2e-07 30.2 16.1 2.2 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family Spore_permease PF03845.11 001280527.1_39725001_2 - 0.00025 19.8 4.5 0.00025 19.8 4.5 2.3 2 0 0 2 2 2 1 Spore germination protein TPR_12 PF13424.4 001246612.1_39724001_2 - 6.7e-16 58.2 8.2 3e-07 30.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.15 001246612.1_39724001_2 - 2.9e-11 42.5 14.1 0.026 14.5 0.7 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.4 001246612.1_39724001_2 - 3.5e-10 39.1 20.9 0.00077 19.4 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.4 001246612.1_39724001_2 - 1.6e-08 33.8 7.7 0.18 11.7 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.4 001246612.1_39724001_2 - 6.9e-08 32.9 0.2 0.015 15.8 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.26 001246612.1_39724001_2 - 1e-06 28.2 18.7 0.37 10.6 0.5 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.4 001246612.1_39724001_2 - 1.6e-06 28.3 2.7 3.3 8.6 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.4 001246612.1_39724001_2 - 0.00013 21.8 0.5 0.033 14.1 0.2 2.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.7 001246612.1_39724001_2 - 0.0002 20.9 10.0 0.044 13.3 0.3 3.5 3 1 2 5 5 5 2 26S proteasome subunit RPN7 TPR_6 PF13174.4 001246612.1_39724001_2 - 0.00043 20.6 10.7 2.4 8.8 0.2 4.8 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_21 PF09976.7 001246612.1_39724001_2 - 0.00057 19.6 1.5 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.4 001246612.1_39724001_2 - 0.0033 17.4 0.3 3.7 7.7 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.5 001246612.1_39724001_2 - 0.005 16.9 15.4 0.013 15.6 1.5 4.5 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.4 001246612.1_39724001_2 - 0.016 15.6 7.9 0.077 13.4 1.3 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.7 001246612.1_39724001_2 - 0.073 12.6 12.0 0.75 9.3 0.1 3.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_11 PF13414.4 001246612.1_39724001_2 - 0.085 12.4 18.7 0.097 12.2 0.3 6.3 6 2 2 8 8 8 0 TPR repeat DUF1266 PF06889.9 001246612.1_39724001_2 - 0.78 9.6 0.0 0.78 9.6 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1266) TPR_20 PF14561.4 001246612.1_39724001_2 - 1.3 9.3 6.4 19 5.5 0.2 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.4 001246612.1_39724001_2 - 1.8 8.4 9.9 5.5 6.9 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Alpha-2-MRAP_C PF06401.9 001246391.1_39724001_3 - 1.3e-70 237.6 26.2 1.4e-69 234.2 19.1 2.1 2 0 0 2 2 2 2 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.9 001246391.1_39724001_3 - 2.2e-45 153.3 11.4 3.2e-41 139.9 0.2 3.3 3 0 0 3 3 3 3 Alpha-2-macroglobulin RAP, N-terminal domain GLYCAM-1 PF05242.9 001246391.1_39724001_3 - 2.4 8.1 6.0 0.53 10.2 1.0 2.2 2 1 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Rieske PF00355.24 001280361.1_39725001_1 - 2.1e-09 37.0 0.1 3.9e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.4 001280361.1_39725001_1 - 1.8e-07 30.8 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain CCDC71L PF15374.4 001246466.1_39724001_1 - 4.6e-182 605.5 46.3 1.2e-180 600.8 37.6 3.0 2 1 0 2 2 2 2 Coiled-coil domain-containing protein 71L PmbA_TldD PF01523.14 001246466.1_39724001_1 - 2.7 7.6 7.6 4.4 6.9 7.6 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DUF1394 PF07159.10 001279971.1_39724001_1 - 2.5e-151 503.0 0.1 3e-151 502.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) V-ATPase_H_N PF03224.12 001279971.1_39724001_1 - 0.05 12.7 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H DnaJ_C PF01556.16 001246534.1_39724001_1 - 6.8e-43 146.2 0.3 9.2e-43 145.7 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.29 001246534.1_39724001_1 - 8.4e-27 93.0 2.6 1.7e-26 92.0 2.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.17 001246534.1_39724001_1 - 1.8e-15 56.9 20.7 3.3e-15 56.1 20.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.3 001246534.1_39724001_1 - 0.098 12.5 12.0 0.93 9.4 4.6 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.17 001246534.1_39724001_1 - 0.14 12.1 7.9 1.4 8.8 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CoA_trans PF01144.21 001280381.1_39724001_2 - 5.1e-127 421.4 1.4 1.5e-77 259.7 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.4 001280381.1_39724001_2 - 0.0025 17.6 0.1 0.0046 16.8 0.1 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain WD40 PF00400.30 001280423.1_39726001_3 - 4.1e-42 141.2 33.0 9.8e-06 26.1 0.2 10.9 10 0 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280423.1_39726001_3 - 1.5e-19 70.0 0.4 0.0018 18.4 0.0 7.5 3 3 5 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001280423.1_39726001_3 - 7e-10 39.0 0.1 0.063 13.0 0.0 4.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001280423.1_39726001_3 - 1.1e-05 24.5 4.3 0.047 12.5 0.0 4.9 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.10 001280423.1_39726001_3 - 0.0015 18.2 0.3 8.4 6.3 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PQQ PF01011.19 001280423.1_39726001_3 - 0.0052 16.5 1.2 0.019 14.7 0.1 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat WD40_like PF17005.3 001280423.1_39726001_3 - 0.028 13.6 0.1 10 5.2 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain IKI3 PF04762.10 001280423.1_39726001_3 - 0.031 12.2 0.0 0.34 8.7 0.0 2.3 2 1 0 3 3 3 0 IKI3 family Nbas_N PF15492.4 001280423.1_39726001_3 - 0.033 13.4 0.5 32 3.6 0.0 4.0 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.4 001280423.1_39726001_3 - 0.044 13.7 0.0 0.52 10.2 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Na_H_Exchanger PF00999.19 001246497.1_39724001_2 - 9.9e-30 103.4 35.2 1.6e-29 102.7 35.2 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-H2C2_2 PF13465.4 001280181.2_39725001_3 - 2.3e-42 141.4 82.9 5.4e-10 39.1 2.4 10.6 11 0 0 11 11 11 7 Zinc-finger double domain zf-H2C2_5 PF13909.4 001280181.2_39725001_3 - 4.6e-35 118.9 58.9 3.3e-05 23.4 0.3 8.3 8 0 0 8 8 8 8 C2H2-type zinc-finger domain zf-C2H2 PF00096.24 001280181.2_39725001_3 - 2.4e-19 68.5 93.2 0.00033 20.8 4.6 10.1 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001280181.2_39725001_3 - 0.019 15.7 2.9 0.019 15.7 2.9 10.1 11 0 0 11 11 11 0 C2H2-type zinc finger zf-C2HE PF16278.3 001280181.2_39725001_3 - 0.068 13.5 38.6 0.89 9.9 0.7 6.8 2 2 5 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.9 001280181.2_39725001_3 - 1.2 8.9 26.7 0.13 12.0 0.9 5.6 2 2 2 5 5 5 0 GAGA factor DUF3505 PF12013.6 001280181.2_39725001_3 - 3 8.2 48.8 0.87 9.9 0.5 8.2 4 2 4 8 8 8 0 Protein of unknown function (DUF3505) GSHPx PF00255.17 001145823.2_39723001_2 - 5.5e-42 141.6 0.1 7.3e-42 141.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.19 001145823.2_39723001_2 - 0.0066 16.2 0.0 0.11 12.3 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family Ribosomal_L16 PF00252.16 001279944.1_39722001_3 - 2.1e-44 150.6 0.3 2.6e-44 150.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e FERM_M PF00373.16 001280226.1_39724001_2 - 3.9e-16 59.4 1.6 7.5e-16 58.5 1.6 1.5 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.8 001280226.1_39724001_2 - 2.6e-15 56.0 0.0 4.8e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain zf-C3HC4_3 PF13920.4 001280226.1_39724001_2 - 7.3e-11 41.6 20.0 3e-10 39.7 20.0 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FERM_C PF09380.8 001280226.1_39724001_2 - 7.4e-05 22.9 0.0 0.00019 21.6 0.0 1.7 2 0 0 2 2 2 1 FERM C-terminal PH-like domain Prok-RING_4 PF14447.4 001280226.1_39724001_2 - 0.018 14.8 21.2 0.018 14.8 21.2 2.7 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 Calponin PF00402.16 001280104.1_39724001_3 - 2e-42 142.3 21.2 2.6e-15 55.6 2.4 3.7 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.29 001280104.1_39724001_3 - 1.7e-23 82.8 0.1 2.4e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.6 001280104.1_39724001_3 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.9 001280104.1_39724001_3 - 0.2 11.9 0.1 0.32 11.2 0.1 1.3 1 0 0 1 1 1 0 CDC24 Calponin STT3 PF02516.12 001246449.1_39726001_3 - 8.5e-166 552.5 41.3 6.9e-161 536.3 36.7 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.4 001246449.1_39726001_3 - 1.5e-05 25.2 13.8 1.5e-05 25.2 13.8 2.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2985 PF11204.6 001246449.1_39726001_3 - 0.25 11.4 4.9 0.52 10.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) DUF2655 PF10848.6 001134339.1_39724001_1 - 0.67 10.2 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2655) MHC_II_alpha PF00993.18 001134339.1_39724001_2 - 2.1e-34 116.9 0.2 3e-34 116.4 0.2 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set_C PF16196.3 001134339.1_39724001_2 - 7.1e-29 98.8 0.1 1.5e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 C1-set C-terminal domain C1-set PF07654.13 001134339.1_39724001_2 - 5e-22 78.0 0.0 1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Marek_A PF02124.13 001134339.1_39724001_2 - 0.00088 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Marek's disease glycoprotein A Ig_3 PF13927.4 001134339.1_39724001_2 - 0.0045 17.4 0.0 0.0083 16.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ras PF00071.20 001280126.1_39724001_1 - 1.7e-64 216.1 0.2 2.2e-64 215.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001280126.1_39724001_1 - 1.7e-33 115.2 0.2 2.5e-33 114.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001280126.1_39724001_1 - 4e-14 52.3 0.1 5.8e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001280126.1_39724001_1 - 0.00011 21.6 0.1 0.00014 21.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.25 001280126.1_39724001_1 - 0.00016 21.2 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.8 001280126.1_39724001_1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001280126.1_39724001_1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3311 PF11755.6 001280126.1_39724001_1 - 0.31 10.9 2.5 0.62 9.9 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) WD40 PF00400.30 001280058.1_39724001_2 - 7e-18 64.5 11.1 0.00022 21.8 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280058.1_39724001_2 - 0.0005 20.2 0.0 14 5.9 0.0 4.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TRAPP PF04051.14 001131004.1_39722001_2 - 1.3e-34 118.9 0.0 1.6e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Fibroin_P25 PF07294.9 001131004.1_39722001_2 - 0.084 12.8 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Fibroin P25 Glycos_transf_1 PF00534.18 001246559.1_39725001_2 - 3.4e-35 121.0 0.0 4.6e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.4 001246559.1_39725001_2 - 7.5e-17 61.9 0.0 1.2e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.4 001246559.1_39725001_2 - 7e-16 58.6 0.1 1.5e-15 57.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.4 001246559.1_39725001_2 - 5.2e-14 52.9 0.2 1e-12 48.7 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.4 001246559.1_39725001_2 - 6.2e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cyclin_C_2 PF16899.3 001082413.2_39723001_3 - 5.7e-27 94.0 0.7 3.3e-25 88.3 0.2 2.6 3 0 0 3 3 3 1 Cyclin C-terminal domain Cyclin_N PF00134.21 001082413.2_39723001_3 - 7.4e-09 35.3 0.2 1.6e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.17 001082413.2_39723001_3 - 0.027 14.4 0.2 0.3 11.1 0.1 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Hepcidin PF06446.10 001109693.1_39721001_3 - 2.4e-21 75.7 12.4 4.6e-21 74.8 12.4 1.5 1 0 0 1 1 1 1 Hepcidin 4F5 PF04419.12 001251925.1_39722001_2 - 7.3e-11 42.6 10.8 7.3e-11 42.6 10.8 3.1 3 0 0 3 3 3 1 4F5 protein family NGP1NT PF08153.10 001246398.2_39725001_1 - 5.1e-48 162.3 1.5 5.1e-48 162.3 1.5 2.4 2 1 1 3 3 3 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.21 001246398.2_39725001_1 - 3.1e-15 56.1 0.0 7.9e-13 48.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.16 001246398.2_39725001_1 - 9.3e-06 25.1 0.0 4.1e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.14 001246398.2_39725001_1 - 0.00038 20.3 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.19 001246398.2_39725001_1 - 0.032 13.6 0.1 0.43 9.9 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF4530 PF15039.4 001246398.2_39725001_1 - 0.75 9.8 5.1 2.9 7.9 5.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) RabGAP-TBC PF00566.16 001280509.1_39725001_3 - 9.3e-50 169.1 12.0 1.6e-49 168.3 12.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.6 001280509.1_39725001_3 - 2.3e-39 134.9 0.3 3.9e-39 134.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3548) Cortex-I_coil PF09304.8 001280509.1_39725001_3 - 1.8 8.7 6.3 0.84 9.7 1.8 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil TSP_C PF05735.10 001098565.1_39726001_1 - 2.9e-97 324.2 0.8 3.9e-97 323.8 0.8 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.16 001098565.1_39726001_1 - 2.4e-61 202.9 135.3 4.7e-12 45.2 12.1 9.3 7 2 1 8 8 8 6 Thrombospondin type 3 repeat COMP PF11598.6 001098565.1_39726001_1 - 2.2e-18 66.3 2.2 4.5e-18 65.3 2.2 1.6 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein EGF_CA PF07645.13 001098565.1_39726001_1 - 1.2e-16 60.4 45.5 7.7e-11 41.9 8.9 5.2 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.5 001098565.1_39726001_1 - 2.5e-08 33.6 4.7 3.4e-05 23.5 0.1 5.4 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF_3 PF12947.5 001098565.1_39726001_1 - 3.3e-08 33.5 45.5 0.00041 20.4 4.6 5.6 5 0 0 5 5 5 3 EGF domain EGF_MSP1_1 PF12946.5 001098565.1_39726001_1 - 0.00021 21.2 2.1 0.00021 21.2 2.1 4.6 4 0 0 4 4 4 1 MSP1 EGF domain 1 EGF PF00008.25 001098565.1_39726001_1 - 0.014 15.6 3.4 0.014 15.6 3.4 5.3 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.5 001098565.1_39726001_1 - 0.02 15.4 0.7 0.02 15.4 0.7 6.7 6 2 0 6 6 6 0 Human growth factor-like EGF HSP20 PF00011.19 001246597.2_39723001_3 - 2.1e-05 24.5 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF2654 PF10849.6 001246597.2_39723001_3 - 0.37 10.9 2.2 2.1 8.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) TOM6p PF15184.4 001256791.1_39722001_2 - 2.7e-49 164.7 0.5 3.5e-49 164.4 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit TOM6 homolog Tom6 PF17112.3 001256791.1_39722001_2 - 0.031 13.6 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal TNFR_c6 PF00020.16 001280397.1_39725001_1 - 6e-23 80.8 43.5 1e-08 35.3 5.6 4.7 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region FixS PF03597.13 001280397.1_39725001_1 - 2.8 7.6 5.4 7.2 6.3 5.4 1.6 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Hormone_1 PF00103.18 001009000.1_39722001_1 - 3.2e-62 210.0 1.6 3.6e-62 209.8 1.6 1.0 1 0 0 1 1 1 1 Somatotropin hormone family DUF498 PF04430.12 001251994.1_39721001_1 - 1.2e-20 73.5 0.0 1.3e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DDE_1 PF03184.17 001243881.2_39728001_2 - 1.1e-41 142.2 0.6 1.8e-41 141.5 0.6 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.14 001243881.2_39728001_2 - 1.1e-15 57.3 0.0 2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.11 001243881.2_39728001_2 - 8.4e-11 41.2 0.1 1.7e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.18 001243881.2_39728001_2 - 0.00066 19.8 0.2 0.0016 18.6 0.2 1.6 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.4 001243881.2_39728001_2 - 0.00088 19.2 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.4 001243881.2_39728001_2 - 0.0017 17.9 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain PCI PF01399.25 001280300.1_39724001_1 - 1e-17 64.4 2.6 1.8e-17 63.6 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_7 PF13176.4 001280300.1_39724001_1 - 0.068 13.1 2.8 2 8.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.4 001280300.1_39724001_1 - 0.3 11.3 4.6 1.3 9.2 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.4 001280300.1_39724001_1 - 1.1 10.2 10.1 4.1 8.3 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.20 001246537.1_39725001_1 - 9.8e-27 92.5 0.0 2e-11 43.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF PF08080.10 001246537.1_39725001_1 - 3.3e-22 78.0 9.1 4e-22 77.7 7.9 1.8 2 0 0 2 2 2 1 RNPHF zinc finger RRM_3 PF08777.9 001246537.1_39725001_1 - 0.0023 17.8 0.0 5.4 7.0 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Spot_14 PF07084.10 001246537.1_39725001_1 - 0.11 12.5 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 DUF2028 PF09667.8 001280179.1_39728001_3 - 1.6e-54 184.7 1.1 3e-54 183.8 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2028) HMG_box PF00505.17 001280179.1_39728001_3 - 5.4e-17 61.8 1.2 1.5e-16 60.4 0.6 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001280179.1_39728001_3 - 2.6e-11 43.8 1.8 1.7e-10 41.2 0.8 2.7 2 0 0 2 2 2 1 HMG-box domain PA26 PF04636.11 001280335.1_39724001_1 - 6.1e-198 658.0 3.1 7.6e-198 657.7 3.1 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.18 001280335.1_39724001_1 - 0.0025 17.7 0.1 0.0084 16.0 0.0 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family RRM_1 PF00076.20 001279816.1_39724001_3 - 1.2e-17 63.3 0.0 1.9e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.6 001279816.1_39724001_3 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 RRM_7 PF16367.3 001279816.1_39724001_3 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.4 001279816.1_39724001_3 - 0.012 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.9 001279816.1_39724001_3 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.4 001279816.1_39724001_3 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.3 001279816.1_39724001_3 - 0.037 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Macoilin PF09726.7 001279816.1_39724001_3 - 0.062 11.7 26.2 0.085 11.3 26.2 1.1 1 0 0 1 1 1 0 Transmembrane protein LAP1C PF05609.10 001279816.1_39724001_3 - 0.68 8.8 17.6 0.98 8.3 17.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sugar_tr PF00083.22 001246591.1_39725001_2 - 6.6e-139 463.5 19.5 7.9e-139 463.3 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.14 001246591.1_39725001_2 - 1.8e-19 69.8 31.7 5e-18 65.0 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tetraspannin PF00335.18 001246591.1_39725001_2 - 0.46 10.1 10.2 2.5 7.7 6.5 2.7 2 0 0 2 2 2 0 Tetraspanin family Phospholip_A2_1 PF00068.17 001329732.1_39722001_2 - 3.6e-35 120.6 13.7 4.7e-35 120.2 13.7 1.1 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.10 001329732.1_39722001_2 - 0.0021 18.1 3.2 0.0021 18.1 3.2 2.5 2 0 0 2 2 2 2 Phospholipase A2 MT-A70 PF05063.12 001246555.1_39724001_3 - 1e-60 204.4 0.0 2e-60 203.5 0.0 1.5 1 0 0 1 1 1 1 MT-A70 DUF445 PF04286.10 001246555.1_39724001_3 - 0.0054 16.5 0.9 0.025 14.3 0.8 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF445) G-patch PF01585.21 001246622.1_39724001_1 - 1.4e-12 47.2 0.7 1.4e-12 47.2 0.7 1.7 2 0 0 2 2 2 1 G-patch domain Ank_4 PF13637.4 001246622.1_39724001_1 - 2.4e-05 24.7 0.0 5.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.5 001246622.1_39724001_1 - 9.5e-05 22.8 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.4 001246622.1_39724001_1 - 0.006 16.9 0.0 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat zf-DBF PF07535.10 001246622.1_39724001_1 - 0.025 14.5 0.4 0.025 14.5 0.4 2.1 2 0 0 2 2 2 0 DBF zinc finger G-patch_2 PF12656.5 001246622.1_39724001_1 - 0.044 13.7 0.4 0.044 13.7 0.4 1.9 2 0 0 2 2 2 0 G-patch domain Ank_5 PF13857.4 001246622.1_39724001_1 - 0.06 13.6 0.3 0.16 12.2 0.3 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.28 001246622.1_39724001_1 - 0.17 12.3 0.1 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat MAGE_N PF12440.6 001246602.1_39725001_3 - 3.1e-27 94.9 15.7 3.1e-27 94.9 15.7 2.0 2 0 0 2 2 2 1 Melanoma associated antigen family N terminal MAGE PF01454.17 001246602.1_39725001_3 - 1.7e-16 60.5 1.4 4.5e-15 55.8 0.0 2.6 2 1 0 2 2 2 1 MAGE family Actin PF00022.17 001246585.1_39724001_2 - 5.7e-99 331.4 0.0 1.9e-97 326.4 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.11 001246585.1_39724001_2 - 0.0011 17.7 0.0 0.12 11.0 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein p450 PF00067.20 001122775.1_39724001_1 - 4.3e-134 447.6 0.2 4.9e-134 447.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Coa1 PF08695.8 001122775.1_39724001_1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 DNA_pol_E_B PF04042.14 001246468.2_39724001_3 - 1.5e-49 168.1 0.1 3.1e-49 167.1 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Endonuclease_5 PF04493.12 001280289.1_39724001_2 - 3.4e-32 111.6 0.0 5.1e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V Endonuclease_5 PF04493.12 001280289.1_39724001_3 - 5.9e-23 81.4 0.0 2.5e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 Endonuclease V TMIE PF16038.3 001280289.1_39724001_3 - 0.023 14.4 0.7 0.044 13.5 0.7 1.4 1 0 0 1 1 1 0 TMIE protein JAB PF01398.19 001280483.1_39724001_3 - 1.3e-18 67.0 0.0 3.2e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.9 001280483.1_39724001_3 - 2.4e-18 66.2 0.1 2.4e-18 66.2 0.1 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.4 001280483.1_39724001_3 - 2.6e-07 30.3 0.1 4.9e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CHDCT2 PF08074.9 001280483.1_39724001_3 - 0.16 12.0 3.6 0.29 11.2 3.6 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain BTB PF00651.29 001280204.1_39725001_3 - 2.3e-25 88.8 2.2 4.3e-25 88.0 2.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.4 001280204.1_39725001_3 - 1.3e-17 63.3 1.0 1.5e-05 24.9 0.0 4.6 3 1 1 4 4 4 3 Kelch motif BACK PF07707.13 001280204.1_39725001_3 - 5.4e-12 45.6 2.0 2.1e-10 40.5 0.5 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.13 001280204.1_39725001_3 - 2.8e-08 33.3 0.4 0.0015 18.3 0.2 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.23 001280204.1_39725001_3 - 3.9e-06 26.2 1.4 0.023 14.1 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.4 001280204.1_39725001_3 - 0.0025 17.6 1.0 0.39 10.6 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain SCRG1 PF15224.4 001242428.1_39723001_3 - 3.8e-48 161.4 6.1 6.9e-48 160.5 6.1 1.4 1 0 0 1 1 1 1 Scrapie-responsive protein 1 GAGA_bind PF06217.10 001246412.1_39724001_2 - 0.11 12.6 0.6 0.17 12.0 0.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family eIF-3_zeta PF05091.10 001246412.1_39724001_3 - 2.7e-217 722.7 3.5 3.2e-217 722.5 3.5 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.7 001246412.1_39724001_3 - 0.0002 20.9 0.0 0.0012 18.3 0.0 2.1 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus DUF2465 PF10239.7 001246541.1_39726001_3 - 2.6e-133 444.1 0.0 3.3e-133 443.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) DUF3585 PF12130.6 001246424.1_39724001_2 - 4.2e-17 62.4 20.4 8.2e-17 61.5 20.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3585) GST_N_3 PF13417.4 001246527.1_39724001_3 - 4.2e-11 42.9 0.1 1.5e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.22 001246527.1_39724001_3 - 2e-08 34.2 0.2 4.2e-08 33.2 0.2 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.4 001246527.1_39724001_3 - 7.2e-08 32.5 0.0 3.1e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.2 001246527.1_39724001_3 - 3.9e-05 24.2 0.2 0.00013 22.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.4 001246527.1_39724001_3 - 4.8e-05 23.1 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.23 001246527.1_39724001_3 - 0.0093 16.0 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001246527.1_39724001_3 - 0.037 14.2 0.1 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.4 001246527.1_39724001_3 - 0.046 13.8 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4201 PF13870.4 001328281.1_39724001_2 - 6.9e-52 175.5 20.8 6.9e-52 175.5 20.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) zf-CHY PF05495.10 001252022.2_39722001_1 - 0.061 13.8 0.9 0.11 13.0 0.9 1.3 1 0 0 1 1 1 0 CHY zinc finger G-gamma PF00631.20 001252022.2_39722001_2 - 2.6e-14 52.8 0.0 4.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 GGL domain PLDc_2 PF13091.4 001246461.1_39726001_3 - 2.9e-26 91.8 0.0 4e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.20 001246461.1_39726001_3 - 0.00084 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif DUF1669 PF07894.10 001246461.1_39726001_3 - 0.0063 16.0 0.1 0.014 14.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1669) CABS1 PF15367.4 001328279.1_39724001_3 - 1.8e-198 659.4 46.0 2e-198 659.2 46.0 1.0 1 0 0 1 1 1 1 Calcium-binding and spermatid-specific protein 1 Septin PF00735.16 001302399.1_39724001_2 - 2e-95 319.1 0.6 4.5e-95 318.0 0.6 1.6 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.21 001302399.1_39724001_2 - 3.7e-05 23.7 0.0 0.0001 22.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.4 001302399.1_39724001_2 - 0.0016 18.6 0.2 0.0043 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.4 001302399.1_39724001_2 - 0.0031 17.8 0.2 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.11 001302399.1_39724001_2 - 0.0035 17.5 0.0 0.0096 16.0 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.25 001302399.1_39724001_2 - 0.012 15.1 3.9 1.8 7.9 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.4 001302399.1_39724001_2 - 0.032 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2959 PF11172.6 001302399.1_39724001_2 - 0.035 14.0 6.6 0.063 13.2 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) IMD PF08397.9 001302399.1_39724001_2 - 0.037 13.3 12.2 0.074 12.3 12.2 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Atg14 PF10186.7 001302399.1_39724001_2 - 0.041 12.8 12.2 0.067 12.1 12.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fzo_mitofusin PF04799.11 001302399.1_39724001_2 - 0.076 12.4 8.2 0.19 11.1 8.2 1.6 1 0 0 1 1 1 0 fzo-like conserved region ABC_tran PF00005.25 001302399.1_39724001_2 - 0.1 13.0 0.3 0.47 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.16 001302399.1_39724001_2 - 0.12 11.6 1.3 7.9 5.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Glucan_synthase PF02364.13 001302399.1_39724001_2 - 0.19 9.7 0.0 0.19 9.7 0.0 1.8 2 0 0 2 2 2 0 1,3-beta-glucan synthase component Dynamin_N PF00350.21 001302399.1_39724001_2 - 0.29 11.1 5.2 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Dynamin family TPR_MLP1_2 PF07926.10 001302399.1_39724001_2 - 0.38 10.7 17.0 0.83 9.6 17.0 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF87 PF01935.15 001302399.1_39724001_2 - 0.47 10.3 5.9 3.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF258 PF03193.14 001302399.1_39724001_2 - 1 9.1 0.0 1 9.1 0.0 2.9 3 1 1 4 4 3 0 Protein of unknown function, DUF258 Exonuc_VII_L PF02601.13 001302399.1_39724001_2 - 1.1 8.6 8.8 1.9 7.9 8.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.10 001302399.1_39724001_2 - 3.9 6.6 14.8 7.3 5.7 14.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.12 001302399.1_39724001_2 - 5 6.7 13.3 8.5 6.0 13.3 1.3 1 0 0 1 1 1 0 IncA protein AAA_11 PF13086.4 001302399.1_39724001_2 - 9.4 5.7 9.6 17 4.9 9.6 1.4 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.21 001328290.1_39725001_3 - 2.2e-91 306.1 1.2 4.4e-91 305.1 0.5 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.3 001328290.1_39725001_3 - 2.5e-16 59.8 0.5 8.4e-16 58.1 0.1 2.2 3 0 0 3 3 3 1 Microtubule binding DUF4498 PF14926.4 001328290.1_39725001_3 - 0.045 12.9 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) Vps5 PF09325.8 001280406.1_39724001_2 - 1e-87 293.5 19.8 1.8e-87 292.7 19.8 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.22 001280406.1_39724001_2 - 3e-30 104.4 0.2 9.2e-29 99.6 0.0 2.6 2 0 0 2 2 2 1 PX domain Sorting_nexin PF03700.11 001280406.1_39724001_2 - 9.7e-28 97.2 11.9 2.3e-27 96.0 11.9 1.6 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain BAR_3_WASP_bdg PF10456.7 001280406.1_39724001_2 - 2.2e-05 23.9 7.5 0.0013 18.1 7.5 2.5 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein FAM92 PF06730.9 001280406.1_39724001_2 - 0.0019 17.6 9.0 0.0035 16.7 9.0 1.4 1 0 0 1 1 1 1 FAM92 protein GrpE PF01025.17 001280406.1_39724001_2 - 0.013 15.1 5.8 0.013 15.1 5.8 2.5 2 1 0 2 2 2 0 GrpE DUF3557 PF12078.6 001280406.1_39724001_2 - 0.1 12.3 0.4 0.22 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3557) DUF3138 PF11336.6 001280406.1_39724001_2 - 0.34 9.3 3.5 0.53 8.7 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) 4HB_MCP_1 PF12729.5 001280406.1_39724001_2 - 0.42 10.0 10.5 0.024 14.1 2.3 2.5 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction Spc7 PF08317.9 001280406.1_39724001_2 - 0.51 9.0 20.4 0.81 8.4 5.1 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Arfaptin PF06456.11 001280406.1_39724001_2 - 0.54 9.7 12.8 1.7 8.0 12.8 1.7 1 1 0 1 1 1 0 Arfaptin-like domain Exonuc_VII_L PF02601.13 001280406.1_39724001_2 - 2.4 7.5 17.4 2.8 7.3 7.2 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Tropomyosin PF00261.18 001280406.1_39724001_2 - 2.4 7.3 16.5 0.02 14.1 4.1 2.4 2 1 0 2 2 2 0 Tropomyosin HR1 PF02185.14 001280406.1_39724001_2 - 2.5 8.2 10.4 0.95 9.5 0.6 3.2 3 0 0 3 3 3 0 Hr1 repeat DUF1870 PF08965.8 001280406.1_39724001_2 - 2.5 8.0 6.7 1.1 9.2 2.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1870) BLOC1_2 PF10046.7 001280406.1_39724001_2 - 4 7.7 13.8 0.84 9.9 1.1 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.16 001280406.1_39724001_2 - 4.8 7.8 7.4 0.48 11.0 1.2 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.8 001280406.1_39724001_2 - 5.1 7.1 10.9 1.3 9.0 2.7 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4618 PF15397.4 001280406.1_39724001_2 - 5.8 6.1 14.8 0.94 8.7 1.5 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) Cementoin PF10511.7 001135851.1_39722001_3 - 6.7e-16 57.2 10.1 8.5e-08 31.7 0.3 3.7 1 1 1 3 3 3 3 Trappin protein transglutaminase binding domain WAP PF00095.19 001135851.1_39722001_3 - 4.4e-09 36.5 10.5 4.4e-09 36.5 10.5 1.8 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF2476 PF10630.7 001246621.1_39724001_3 - 3.7e-112 374.6 16.4 5.6e-112 374.0 16.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2476) 7tm_1 PF00001.19 001246366.1_39724001_1 - 1.2e-32 113.1 21.2 2.4e-32 112.1 21.2 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ig PF00047.23 001104608.1_39723001_1 - 3.2e-14 52.7 0.0 1.9e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001104608.1_39723001_1 - 8.1e-07 29.4 0.0 0.00086 19.7 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.4 001104608.1_39723001_1 - 0.00025 21.2 0.0 0.0013 18.9 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin domain SIT PF15330.4 001104608.1_39723001_1 - 0.0068 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT MFS_1 PF07690.14 001280461.1_39724001_2 - 1.4e-34 119.4 42.5 6.8e-22 77.7 28.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.4 001328326.1_39723001_2 - 8.3e-14 51.4 5.6 3.4e-13 49.5 5.6 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.3 001328326.1_39723001_2 - 1.4e-12 47.0 1.7 1.4e-12 47.0 1.7 2.5 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.4 001328326.1_39723001_2 - 1.1e-09 37.8 5.2 2.8e-09 36.5 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001328326.1_39723001_2 - 6.2e-09 35.5 4.5 1.6e-08 34.1 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.20 001328326.1_39723001_2 - 1.2e-08 34.8 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_UBOX PF13445.4 001328326.1_39723001_2 - 1.5e-08 34.4 3.5 1.7e-08 34.2 1.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.4 001328326.1_39723001_2 - 1.2e-07 31.4 3.9 3.7e-07 29.9 3.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.5 001328326.1_39723001_2 - 6.8e-07 29.3 6.2 2.7e-06 27.5 6.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.4 001328326.1_39723001_2 - 3.3e-05 23.5 3.6 9.7e-05 22.0 3.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.4 001328326.1_39723001_2 - 0.00015 21.4 3.7 0.00035 20.2 3.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.5 001328326.1_39723001_2 - 0.00023 21.0 4.7 0.00081 19.3 4.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.3 001328326.1_39723001_2 - 0.013 15.0 3.3 0.034 13.6 3.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.27 001328326.1_39723001_2 - 0.015 15.1 3.9 0.04 13.7 3.9 1.8 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.4 001328326.1_39723001_2 - 0.02 14.7 4.2 0.23 11.3 1.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.5 001328326.1_39723001_2 - 0.022 14.8 4.0 0.022 14.8 4.0 2.0 2 0 0 2 2 1 0 RING-variant domain zf-Nse PF11789.6 001328326.1_39723001_2 - 0.064 12.9 2.9 0.23 11.2 2.9 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.6 001328326.1_39723001_2 - 0.65 10.1 5.3 4.6 7.4 5.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.3 001328326.1_39723001_2 - 8.9 6.3 9.3 1.6 8.7 4.3 2.5 2 1 0 2 2 1 0 Zinc-finger Dus PF01207.15 001280052.1_39725001_2 - 2.8e-51 174.3 0.2 4.4e-51 173.7 0.2 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) dsrm PF00035.24 001280052.1_39725001_2 - 7.4e-07 29.6 0.0 1.6e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif His_biosynth PF00977.19 001280052.1_39725001_2 - 0.017 14.5 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TPP_enzyme_N PF02776.16 001280120.1_39724001_2 - 1.4e-44 151.6 0.1 1.9e-43 147.9 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.20 001280120.1_39724001_2 - 1.5e-32 112.1 0.0 3.2e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.19 001280120.1_39724001_2 - 3.2e-25 88.6 0.1 1.5e-24 86.4 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.14 001280120.1_39724001_2 - 8.8e-05 22.2 0.0 8.8e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit tRNA_m1G_MT PF01746.19 001243944.1_39724001_2 - 4.8e-40 137.2 0.0 9.3e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Pkinase PF00069.23 001302422.1_39725001_3 - 5.9e-69 232.2 0.0 7.7e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001302422.1_39725001_3 - 1.9e-35 122.2 0.0 3.4e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001302422.1_39725001_3 - 5.3e-07 29.1 0.1 1.6e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.22 001302422.1_39725001_3 - 4.9e-06 27.0 0.1 1.1e-05 25.9 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.12 001302422.1_39725001_3 - 0.0097 15.1 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.4 001302422.1_39725001_3 - 0.018 14.5 0.2 1.8 8.0 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PX PF00787.22 001302422.1_39725001_3 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 PX domain JmjC PF02373.20 001280223.1_39724001_2 - 2.8e-29 101.8 0.0 5e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.4 001280223.1_39724001_2 - 3e-18 66.4 0.1 6.8e-18 65.2 0.1 1.5 1 1 0 1 1 1 1 Cupin-like domain AF-4 PF05110.11 001280223.1_39724001_2 - 0.083 10.9 13.5 0.13 10.2 13.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMUP PF15761.3 001280223.1_39724001_2 - 0.14 12.7 12.0 0.33 11.5 12.0 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.7 001280223.1_39724001_2 - 0.42 10.1 16.4 0.097 12.1 11.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Humanin PF15040.4 001193641.1_39724001_3 - 1.1e-14 53.4 1.3 2e-14 52.6 1.3 1.5 1 0 0 1 1 1 1 Humanin family Filament PF00038.19 001144838.1_39724001_1 - 2.5e-118 395.0 28.9 3e-118 394.8 28.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.10 001144838.1_39724001_1 - 0.0096 15.8 1.0 0.0096 15.8 1.0 4.0 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Glyco_hyd_65N_2 PF14498.4 001144838.1_39724001_1 - 0.086 12.5 0.2 0.25 11.1 0.2 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain zf-C4H2 PF10146.7 001144838.1_39724001_1 - 0.5 10.5 16.0 0.27 11.4 3.9 2.9 2 1 1 3 3 3 0 Zinc finger-containing protein Cep57_MT_bd PF06657.11 001144838.1_39724001_1 - 3.2 8.1 17.3 11 6.5 0.8 4.6 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.4 001144838.1_39724001_1 - 4.3 6.5 16.1 4.6 6.4 6.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Reo_sigmaC PF04582.10 001144838.1_39724001_1 - 5.4 6.2 9.5 16 4.7 5.6 3.0 3 1 1 4 4 4 0 Reovirus sigma C capsid protein MtrE PF04206.10 001144838.1_39724001_2 - 0.43 9.7 4.7 0.62 9.2 4.7 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E Tubulin PF00091.23 001246392.1_39724001_3 - 7.2e-65 218.8 0.0 1e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001246392.1_39724001_3 - 3.2e-30 104.8 0.0 5.6e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.4 001246392.1_39724001_3 - 0.00068 18.8 0.0 0.00099 18.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.4 001246392.1_39724001_3 - 0.0027 17.3 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain CHORD PF04968.10 001246422.1_39725001_1 - 5.2e-55 183.9 17.0 1.3e-28 99.3 2.4 2.5 2 0 0 2 2 2 2 CHORD CS PF04969.14 001246422.1_39725001_1 - 3.1e-14 53.6 0.2 5.2e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 CS domain BTK PF00779.17 001246422.1_39725001_1 - 1.3 8.7 12.1 1.4 8.6 0.4 3.2 3 1 0 3 3 3 0 BTK motif Ribosomal_S10 PF00338.20 001251970.1_39722001_2 - 2.8e-16 59.4 0.0 5.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pkinase PF00069.23 001246509.1_39724001_2 - 1.7e-46 158.6 0.2 2.2e-46 158.3 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001246509.1_39724001_2 - 1.7e-21 76.6 0.3 6.3e-21 74.7 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase SR-25 PF10500.7 001246509.1_39724001_2 - 1.5 8.2 24.3 3.2 7.2 24.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F-box-like PF12937.5 001280327.1_39724001_3 - 0.076 12.8 1.3 0.15 11.9 1.3 1.4 1 0 0 1 1 1 0 F-box-like Tektin PF03148.12 001279940.1_39724001_1 - 6.7e-138 459.5 25.7 7.8e-138 459.2 25.7 1.0 1 0 0 1 1 1 1 Tektin family JIP_LZII PF16471.3 001279940.1_39724001_1 - 3 8.0 10.9 10 6.3 0.3 4.3 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II Lzipper-MIP1 PF14389.4 001279940.1_39724001_1 - 3.1 8.0 7.8 0.55 10.4 0.4 3.3 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Laminin_II PF06009.10 001279940.1_39724001_1 - 3.2 7.6 7.2 12 5.7 0.2 3.5 4 0 0 4 4 4 0 Laminin Domain II SPAN-X PF07458.10 001009155.1_39721001_1 - 1.2e-39 134.5 2.4 1.5e-39 134.2 2.4 1.1 1 0 0 1 1 1 1 Sperm protein associated with nucleus, mapped to X chromosome DUF3749 PF12568.6 001009155.1_39721001_1 - 0.068 12.8 0.1 0.089 12.4 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L11_N PF03946.12 001251929.1_39722001_2 - 2.5e-26 91.1 0.1 4.5e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.17 001251929.1_39722001_2 - 4.8e-19 68.5 0.1 7.5e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain tRNA-synt_2d PF01409.18 001246463.1_39724001_1 - 7.8e-48 163.0 1.4 4e-30 105.0 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.12 001246463.1_39724001_1 - 8.4e-22 77.3 0.1 2.6e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.18 001246463.1_39724001_1 - 0.0084 15.1 0.1 0.72 8.7 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) ubiquitin PF00240.21 001280202.1_39725001_3 - 3.8e-18 64.8 0.0 7.6e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.14 001280202.1_39725001_3 - 1.1e-08 34.9 8.3 1.1e-08 34.9 8.3 2.8 2 0 0 2 2 2 1 AN1-like Zinc finger Rad60-SLD PF11976.6 001280202.1_39725001_3 - 0.0003 20.4 0.0 0.00076 19.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001280202.1_39725001_3 - 0.012 15.9 0.0 0.046 14.0 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain RNA_pol_Rpb4 PF03874.14 001242429.1_39726001_2 - 2.6e-30 105.2 6.3 3.5e-30 104.7 6.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Muted PF14942.4 001242429.1_39726001_2 - 0.13 12.4 4.5 0.06 13.5 0.9 2.1 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Tantalus PF15386.4 001280324.1_39725001_1 - 8.2e-24 83.3 1.9 1.5e-23 82.5 1.9 1.5 1 0 0 1 1 1 1 Drosophila Tantalus-like Kelch_1 PF01344.23 001279961.1_39726001_2 - 1.5e-85 280.4 14.8 5e-17 61.1 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.4 001279961.1_39726001_2 - 1.4e-50 167.9 6.0 8.1e-11 41.7 0.1 6.6 2 2 4 6 6 6 6 Kelch motif BACK PF07707.13 001279961.1_39726001_2 - 3.5e-33 113.7 0.9 7.6e-33 112.6 0.9 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.4 001279961.1_39726001_2 - 1.6e-32 111.0 15.6 2.1e-07 30.9 0.4 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.29 001279961.1_39726001_2 - 4.9e-30 103.9 0.2 7.8e-30 103.2 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.13 001279961.1_39726001_2 - 9.1e-29 98.2 3.3 3.2e-07 29.9 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.4 001279961.1_39726001_2 - 1.3e-21 76.2 6.9 0.00044 20.0 0.1 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.4 001279961.1_39726001_2 - 0.0019 18.0 16.8 0.84 9.6 0.1 6.4 7 0 0 7 7 7 2 Kelch motif DEAD PF00270.27 001246588.1_39724001_1 - 1.7e-46 158.1 0.0 4.4e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001246588.1_39724001_1 - 1.9e-28 98.9 0.1 7.2e-28 97.0 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.13 001246588.1_39724001_1 - 9.5e-07 28.8 0.0 2.7e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.4 001246588.1_39724001_1 - 0.074 13.2 0.1 0.41 10.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain Radical_SAM PF04055.19 001246588.1_39724001_1 - 0.087 13.1 0.5 0.94 9.7 0.0 2.4 2 1 0 2 2 2 0 Radical SAM superfamily Pkinase PF00069.23 001145037.1_39724001_1 - 1.3e-54 185.2 1.2 1.8e-54 184.8 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001145037.1_39724001_1 - 1.3e-35 122.9 0.1 2.8e-29 102.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase dsrm PF00035.24 001145037.1_39724001_1 - 5.8e-28 97.3 7.6 4.2e-14 52.8 0.0 3.7 4 0 0 4 4 4 2 Double-stranded RNA binding motif Kinase-like PF14531.4 001145037.1_39724001_1 - 9.2e-05 21.8 0.0 0.0032 16.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.12 001145037.1_39724001_1 - 0.016 14.5 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DND1_DSRM PF14709.5 001145037.1_39724001_1 - 0.02 15.0 0.0 0.95 9.6 0.0 2.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 FTA2 PF13095.4 001145037.1_39724001_1 - 0.046 13.2 0.3 0.59 9.6 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.9 001145037.1_39724001_1 - 0.1 11.4 0.6 4.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase zf-MYND PF01753.16 001246503.1_39724001_1 - 1.7e-07 31.1 24.9 5e-07 29.6 24.9 1.9 1 0 0 1 1 1 1 MYND finger Mo25 PF08569.9 001246503.1_39724001_1 - 0.043 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Mo25-like Arm_2 PF04826.11 001279976.1_39724001_1 - 1.7e-112 374.9 5.0 2.1e-112 374.6 5.0 1.1 1 0 0 1 1 1 1 Armadillo-like Atx10homo_assoc PF09759.7 001279976.1_39724001_1 - 0.0017 18.3 0.5 0.12 12.3 0.2 3.4 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.21 001279976.1_39724001_1 - 0.048 13.6 1.4 1.3 9.0 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PUL PF08324.9 001279976.1_39724001_1 - 0.2 10.8 5.0 0.26 10.4 4.0 1.6 1 1 1 2 2 2 0 PUL domain PNRC PF15365.4 001252002.1_39724001_2 - 5.5e-10 39.5 11.9 1.2e-09 38.5 6.7 2.9 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator Pkinase PF00069.23 001280514.1_39725001_2 - 1.1e-61 208.5 1.1 2.3e-61 207.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280514.1_39725001_2 - 1e-41 142.9 0.1 2.1e-41 141.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.4 001280514.1_39725001_2 - 2.9e-05 23.4 0.4 9.7e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.21 001280514.1_39725001_2 - 0.053 13.3 0.1 0.053 13.3 0.1 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ig_3 PF13927.4 001034162.1_39728001_1 - 1.7e-75 249.5 3.4 3.5e-12 46.6 0.1 7.0 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.14 001034162.1_39728001_1 - 3.4e-72 238.4 0.0 1.1e-13 50.9 0.1 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.19 001034162.1_39728001_1 - 2.2e-57 191.2 9.8 1.3e-14 54.2 0.1 4.8 4 0 0 4 4 4 4 Fibronectin type III domain Ig_2 PF13895.4 001034162.1_39728001_1 - 4.4e-49 164.6 0.7 2.2e-09 37.4 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.23 001034162.1_39728001_1 - 5e-46 154.7 0.0 3.2e-09 36.7 0.1 7.1 6 0 0 6 6 6 6 Immunoglobulin domain Bravo_FIGEY PF13882.4 001034162.1_39728001_1 - 5.5e-27 94.8 6.7 1.1e-26 93.8 6.7 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region Ig_5 PF16681.3 001034162.1_39728001_1 - 1.3e-10 41.4 0.0 0.0035 17.6 0.0 5.6 5 1 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.15 001034162.1_39728001_1 - 3.1e-10 40.0 8.2 1.4 9.0 0.8 9.6 7 4 2 9 9 9 2 Immunoglobulin V-set domain C2-set_2 PF08205.10 001034162.1_39728001_1 - 8.8e-10 38.4 0.2 0.024 14.6 0.0 5.9 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.3 001034162.1_39728001_1 - 3.2e-06 27.3 0.2 1.2 9.5 0.0 5.6 6 0 0 6 6 5 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.9 001034162.1_39728001_1 - 5.4e-05 23.0 0.4 1.2 9.0 0.0 4.0 3 1 0 3 3 3 2 CD47 immunoglobulin-like domain Izumo-Ig PF16706.3 001034162.1_39728001_1 - 0.0011 18.9 0.0 3.6 7.6 0.0 3.7 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain fn3_2 PF16893.3 001034162.1_39728001_1 - 0.0015 18.5 0.3 0.034 14.1 0.1 2.7 2 1 0 2 2 2 1 Fibronectin type III domain SIT PF15330.4 001034162.1_39728001_1 - 0.0029 17.9 0.0 0.24 11.7 0.0 2.5 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT C1-set PF07654.13 001034162.1_39728001_1 - 0.0031 17.8 0.1 22 5.5 0.0 4.2 3 0 0 3 3 3 0 Immunoglobulin C1-set domain INCA1 PF15142.4 001034162.1_39728001_1 - 0.14 12.0 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 INCA1 Adeno_E3_CR1 PF02440.13 001034162.1_39728001_1 - 1.8 8.3 5.8 31 4.3 0.0 4.5 6 1 0 6 6 5 0 Adenovirus E3 region protein CR1 Peptidase_C54 PF03416.17 001246528.2_39724001_3 - 9.7e-100 333.2 0.0 1.2e-99 332.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.29 001279946.1_39726001_2 - 3.3e-26 91.1 3.1 4.9e-26 90.5 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1777 PF08648.10 001279946.1_39726001_2 - 0.06 13.5 3.8 3.6 7.7 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Ig_3 PF13927.4 001193680.1_39728001_1 - 3.3e-74 245.4 0.4 5.2e-13 49.3 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.14 001193680.1_39728001_1 - 1.1e-68 227.2 0.0 1.8e-12 47.0 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.19 001193680.1_39728001_1 - 2.4e-65 216.7 13.0 1.1e-16 60.8 0.1 6.0 6 0 0 6 6 6 5 Fibronectin type III domain Ig_2 PF13895.4 001193680.1_39728001_1 - 2.5e-46 155.8 0.2 1.8e-07 31.3 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.23 001193680.1_39728001_1 - 5.3e-43 145.0 0.1 8.5e-07 28.9 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin domain Bravo_FIGEY PF13882.4 001193680.1_39728001_1 - 4.5e-27 95.1 6.2 1.1e-26 93.9 6.2 1.7 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.15 001193680.1_39728001_1 - 1.2e-17 63.9 12.2 0.0078 16.2 0.0 10.9 7 6 2 10 10 10 3 Immunoglobulin V-set domain C2-set_2 PF08205.10 001193680.1_39728001_1 - 3e-12 46.3 0.7 0.32 11.0 0.0 6.0 6 0 0 6 6 6 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.3 001193680.1_39728001_1 - 4.6e-08 33.2 0.0 0.1 12.9 0.0 5.7 6 0 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001193680.1_39728001_1 - 1.2e-07 32.0 3.9 2.4 8.6 0.0 5.8 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain BiPBP_C PF06832.10 001193680.1_39728001_1 - 6.8e-05 22.7 0.0 0.49 10.3 0.0 4.4 4 0 0 4 4 4 1 Penicillin-Binding Protein C-terminus Family Izumo-Ig PF16706.3 001193680.1_39728001_1 - 0.00011 22.1 0.1 0.28 11.1 0.0 4.6 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.3 001193680.1_39728001_1 - 0.032 14.5 0.1 6.8 7.0 0.0 4.4 5 1 0 5 5 5 0 T-cell surface glycoprotein CD3 delta chain Interfer-bind PF09294.8 001193680.1_39728001_1 - 0.062 13.5 0.0 1.5 9.1 0.0 3.2 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III EVC2_like PF12297.6 001193680.1_39728001_1 - 0.28 9.7 0.0 0.4 9.2 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein SH3_9 PF14604.4 001252004.1_39722001_1 - 0.3 10.9 0.1 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 Variant SH3 domain Got1 PF04178.10 001252004.1_39722001_2 - 1.9e-17 63.6 16.8 2.7e-17 63.1 16.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.11 001252004.1_39722001_2 - 0.73 10.1 20.2 0.058 13.6 11.6 2.3 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Dynamin_M PF01031.18 001279836.1_39724001_1 - 1.1e-87 293.8 11.7 1.1e-87 293.8 11.7 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.21 001279836.1_39724001_1 - 3.2e-50 170.3 2.0 5.2e-50 169.7 0.2 2.3 2 0 0 2 2 2 1 Dynamin family GED PF02212.16 001279836.1_39724001_1 - 5.6e-26 90.4 1.0 5.6e-26 90.4 1.0 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.21 001279836.1_39724001_1 - 0.00039 20.3 4.1 0.0018 18.2 0.7 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_21 PF13304.4 001279836.1_39724001_1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2120 PF09893.7 001279836.1_39724001_1 - 0.018 15.0 0.4 0.12 12.3 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) AAA_29 PF13555.4 001279836.1_39724001_1 - 0.022 14.3 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.4 001279836.1_39724001_1 - 0.033 14.4 1.3 0.79 9.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.25 001279836.1_39724001_1 - 0.13 12.7 2.8 0.15 12.4 0.0 2.5 2 1 0 2 2 2 0 ABC transporter PP_kinase_N PF13089.4 001279836.1_39724001_1 - 0.54 10.5 5.3 0.84 9.9 1.4 3.1 2 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain PAP_assoc PF03828.17 001280366.1_39726001_3 - 6.6e-06 26.1 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase RRM_1 PF00076.20 001280366.1_39726001_3 - 2.3e-05 24.0 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.5 001280366.1_39726001_3 - 0.00015 21.9 0.7 0.00032 20.9 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type RRM_7 PF16367.3 001280366.1_39726001_3 - 0.033 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif tRNA_NucTransf2 PF09249.9 001280366.1_39726001_3 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain DUF4632 PF15451.4 001280366.1_39726001_3 - 0.13 12.3 3.5 0.41 10.6 3.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) zf-C2H2_2 PF12756.5 001280366.1_39726001_3 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Integrin_alpha2 PF08441.10 001034169.1_39728001_1 - 7e-38 130.6 0.0 9.9e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.26 001034169.1_39728001_1 - 1.8e-31 109.6 1.1 2.6e-31 109.1 1.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.21 001034169.1_39728001_1 - 1.1e-18 66.9 6.6 4.6e-08 32.9 0.4 4.1 4 0 0 4 4 4 3 FG-GAP repeat VWA_2 PF13519.4 001034169.1_39728001_1 - 7.8e-10 39.2 0.2 2.9e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VCBS PF13517.4 001034169.1_39728001_1 - 1.1e-08 35.4 0.2 1.1e-05 25.8 0.1 3.0 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.4 001034169.1_39728001_1 - 0.00011 22.3 9.1 0.047 13.8 0.0 4.6 4 0 0 4 4 4 2 FG-GAP repeat Integrin_alpha PF00357.18 001034169.1_39728001_1 - 0.00012 21.6 0.4 0.0003 20.4 0.4 1.7 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region FAST_2 PF08368.10 001280083.1_39724001_2 - 6.4e-17 62.0 0.0 1.6e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.13 001280083.1_39724001_2 - 5.1e-14 51.8 0.3 5.1e-14 51.8 0.3 2.2 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 1 RAP PF08373.8 001280083.1_39724001_2 - 2.8e-07 30.4 0.0 5.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RAP domain Surp PF01805.18 001246595.1_39725001_2 - 1.8e-30 104.6 3.0 3.1e-16 59.0 0.1 2.8 2 0 0 2 2 2 2 Surp module G-patch PF01585.21 001246595.1_39725001_2 - 1.1e-15 57.1 3.5 2.8e-15 55.8 3.5 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.5 001246595.1_39725001_2 - 8.5e-07 28.8 1.8 6e-06 26.1 0.5 2.6 2 0 0 2 2 2 1 G-patch domain Tuberculin PF12198.6 001246595.1_39725001_2 - 0.11 12.5 3.5 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 Theoretical tuberculin protein RtcB PF01139.15 001246595.1_39725001_2 - 0.13 11.2 1.1 0.24 10.4 1.1 1.3 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB HEAT PF02985.20 001280390.1_39727001_3 - 1.4e-21 74.5 2.5 5.6e-05 22.9 0.0 9.4 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.4 001280390.1_39727001_3 - 1.8e-20 73.0 0.7 8.7e-09 35.5 0.0 7.4 5 3 3 8 8 8 3 HEAT repeats HEAT_EZ PF13513.4 001280390.1_39727001_3 - 5.2e-18 65.0 6.8 6.5e-08 32.8 0.0 8.4 9 2 2 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.5 001280390.1_39727001_3 - 1.8e-16 60.3 8.9 2.4e-06 27.9 0.0 8.2 6 2 1 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.5 001280390.1_39727001_3 - 6.9e-07 29.3 8.0 7.9e-05 22.6 0.1 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.6 001280390.1_39727001_3 - 1e-06 28.6 8.4 2.2 8.0 0.0 8.4 6 2 3 10 10 10 2 Domain of unknown function (DUF3385) IBN_N PF03810.17 001280390.1_39727001_3 - 4.3e-05 23.2 2.5 0.00029 20.6 0.1 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.21 001280390.1_39727001_3 - 0.00023 21.0 0.4 21 5.2 0.0 5.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.14 001280390.1_39727001_3 - 0.0028 18.1 1.1 1.6 9.5 0.0 4.5 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat RTP1_C1 PF10363.7 001280390.1_39727001_3 - 0.0043 17.1 0.1 0.72 9.9 0.0 4.3 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 AAA_30 PF13604.4 001280390.1_39727001_3 - 0.034 13.7 2.7 4.9 6.7 0.0 3.6 3 1 0 3 3 3 0 AAA domain IKKbetaNEMObind PF12179.6 001280221.1_39727001_1 - 5.3e-10 39.0 0.4 1e-09 38.1 0.4 1.5 1 0 0 1 1 1 1 I-kappa-kinase-beta NEMO binding domain Pkinase PF00069.23 001280221.1_39727001_3 - 3.7e-48 164.1 0.0 6.4e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280221.1_39727001_3 - 5.5e-34 117.5 0.0 9.4e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.12 001280221.1_39727001_3 - 0.0016 17.7 0.1 0.0038 16.5 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AXH PF08517.10 001246397.2_39725001_3 - 1.4e-33 115.7 0.2 4.9e-33 113.9 0.0 1.9 2 0 0 2 2 2 1 Ataxin-1 and HBP1 module (AXH) HMG_box PF00505.17 001246397.2_39725001_3 - 1e-14 54.5 0.9 2.1e-14 53.5 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.8 001246397.2_39725001_3 - 3.9e-09 36.8 1.6 8.9e-09 35.7 1.6 1.6 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.10 001246397.2_39725001_3 - 0.0034 16.6 0.2 0.0074 15.5 0.2 1.5 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Crystall PF00030.17 001135660.1_39722001_1 - 3.9e-63 209.5 0.9 3.4e-31 107.1 0.6 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.11 001135660.1_39722001_1 - 0.0036 17.1 0.4 0.13 12.1 0.1 2.5 2 1 0 2 2 2 1 Peptidase inhibitor family I36 Crystall_3 PF08964.8 001135660.1_39722001_1 - 0.049 13.7 0.1 0.97 9.5 0.1 2.6 2 1 1 3 3 3 0 Beta/Gamma crystallin Med20 PF08612.9 001246490.1_39725001_1 - 1.6e-47 161.6 0.0 2.2e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Choline_kinase PF01633.18 001280076.1_39724001_2 - 1.9e-76 256.3 0.1 2.7e-76 255.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.21 001280076.1_39724001_2 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.18 001280076.1_39724001_2 - 1.2e-05 24.7 0.0 2.4e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.12 001280076.1_39724001_2 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.20 001205232.1_39729001_2 - 2.3e-08 33.6 0.0 0.0025 17.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.6 001205232.1_39729001_2 - 0.032 14.4 8.8 1.8 8.9 1.1 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PHD PF00628.27 001280317.1_39725001_2 - 1.1e-10 41.1 31.5 4.5e-09 35.9 8.5 3.1 3 1 0 3 3 3 2 PHD-finger Mtf2_C PF14061.4 001280317.1_39725001_2 - 5.2e-08 32.8 0.3 1.5e-07 31.3 0.3 1.7 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 PHD_2 PF13831.4 001280317.1_39725001_2 - 0.00033 20.0 4.1 0.00033 20.0 4.1 2.8 2 0 0 2 2 2 1 PHD-finger Chromo PF00385.22 001280317.1_39725001_2 - 0.0052 16.5 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4537 PF15057.4 001280317.1_39725001_2 - 0.0091 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) C1_1 PF00130.20 001280317.1_39725001_2 - 0.4 10.5 21.5 0.028 14.2 4.4 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.4 001280317.1_39725001_2 - 8.8 6.1 17.9 1.6 8.5 5.4 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon ADIP PF11559.6 001280129.1_39725001_1 - 4e-43 147.0 19.2 4e-43 147.0 19.2 3.8 2 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding Ig_2 PF13895.4 001009055.2_39725001_1 - 5.4e-34 116.2 0.3 6.6e-14 51.9 0.1 4.3 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.4 001009055.2_39725001_1 - 5.8e-22 78.0 0.4 0.00082 19.8 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.23 001009055.2_39725001_1 - 1.3e-17 63.6 0.0 0.00038 20.4 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain DUF4692 PF15763.3 001009055.2_39725001_1 - 0.072 13.5 0.9 0.27 11.6 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4692) TMEM51 PF15345.4 001009055.2_39725001_1 - 0.87 9.2 3.5 2.2 7.9 3.5 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 BTB PF00651.29 001280354.1_39727001_3 - 5e-28 97.4 1.3 3.3e-14 52.9 0.0 3.7 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.20 001280354.1_39727001_3 - 1.4e-23 83.1 0.0 2.7e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001280354.1_39727001_3 - 2.5e-09 37.3 0.0 5.5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SIX1_SD PF16878.3 001280354.1_39727001_3 - 8.2 6.9 7.8 13 6.3 3.0 2.9 3 0 0 3 3 3 0 Transcriptional regulator, SIX1, N-terminal SD domain BIR PF00653.19 001246507.1_39724001_3 - 3.5e-23 81.9 2.3 8.6e-23 80.7 2.3 1.7 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain TIR_2 PF13676.4 001130461.1_39722001_1 - 1e-10 41.7 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.18 001130461.1_39722001_1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain SH3_1 PF00018.26 001246580.1_39724001_2 - 2.6e-43 145.3 5.4 1e-14 53.7 0.1 3.6 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.4 001246580.1_39724001_2 - 6.1e-40 134.7 1.1 7.1e-13 48.1 0.0 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.15 001246580.1_39724001_2 - 2.5e-34 116.6 1.9 3.8e-11 42.4 0.1 3.7 3 1 1 4 4 4 3 Variant SH3 domain SH2 PF00017.22 001246580.1_39724001_2 - 3.1e-23 81.5 0.2 6e-23 80.6 0.2 1.5 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.9 001246580.1_39724001_2 - 1.9e-07 31.1 7.2 0.14 12.3 0.2 3.3 3 0 0 3 3 3 3 Bacterial SH3 domain hSH3 PF14603.4 001246580.1_39724001_2 - 0.00095 19.5 0.1 0.15 12.4 0.0 2.7 2 0 0 2 2 2 1 Helically-extended SH3 domain SH2_2 PF14633.4 001246580.1_39724001_2 - 0.0038 16.5 0.1 0.011 15.0 0.1 1.7 1 1 0 1 1 1 1 SH2 domain TIR PF01582.18 001130465.1_39725001_1 - 4.2e-27 95.0 0.4 1e-26 93.7 0.4 1.7 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001130465.1_39725001_1 - 8.7e-21 73.3 36.3 6.8e-11 41.6 3.4 7.8 3 2 6 9 9 9 8 Leucine rich repeat LRR_4 PF12799.5 001130465.1_39725001_1 - 1.7e-19 69.4 41.9 2e-05 24.7 0.2 9.2 6 2 3 9 9 9 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001130465.1_39725001_1 - 3.7e-12 46.3 0.0 9.4e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.4 001130465.1_39725001_1 - 2.6e-07 30.2 6.7 0.044 13.1 0.2 3.5 3 0 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.4 001130465.1_39725001_1 - 4.5e-05 23.0 25.5 3.8 7.7 0.2 10.2 10 0 0 10 10 10 2 Leucine Rich repeat LRRCT PF01463.22 001130465.1_39725001_1 - 4.7e-05 23.5 0.1 0.00016 21.8 0.1 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001130465.1_39725001_1 - 0.11 13.0 35.8 7.6 7.3 0.1 10.8 10 2 0 10 10 10 0 Leucine Rich Repeat CD20 PF04103.13 001246441.1_39724001_3 - 0.016 15.2 3.6 0.016 15.2 3.6 2.0 1 1 1 2 2 2 0 CD20-like family SR-25 PF10500.7 001246441.1_39724001_3 - 0.79 9.2 16.7 1.2 8.5 16.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AP3D1 PF06375.9 001246441.1_39724001_3 - 7.5 6.7 15.6 12 6.1 15.6 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 F-actin_cap_A PF01267.15 001280282.1_39725001_2 - 8.4e-107 356.4 0.9 1e-106 356.1 0.9 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Pkinase PF00069.23 001280292.1_39725001_1 - 9.8e-50 169.2 0.0 1.9e-49 168.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280292.1_39725001_1 - 2.7e-25 89.0 0.0 3.9e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001280292.1_39725001_1 - 2.6e-05 24.1 0.1 0.00013 21.8 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.4 001280292.1_39725001_1 - 0.016 14.4 0.2 0.039 13.1 0.2 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.12 001280292.1_39725001_1 - 0.027 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.9 001280292.1_39725001_1 - 0.037 12.9 0.1 0.054 12.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Dynein_light PF01221.16 001246358.2_39723001_1 - 2.4e-26 91.7 0.1 3.7e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 IIGP PF05049.11 001160207.2_39724001_2 - 3.2e-64 217.2 0.0 4e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Thioredoxin PF00085.18 001246506.1_39724001_3 - 3.2e-11 42.9 0.0 5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF1510 PF07423.9 001246506.1_39724001_3 - 2.5e-05 23.7 7.5 3.8e-05 23.1 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) FAM176 PF14851.4 001246506.1_39724001_3 - 0.0017 18.0 1.1 0.0017 18.0 1.1 2.3 1 1 1 2 2 2 1 FAM176 family CDC45 PF02724.12 001246506.1_39724001_3 - 0.013 13.7 4.2 0.017 13.3 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4834 PF16118.3 001246506.1_39724001_3 - 0.027 15.3 0.0 0.056 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) IncA PF04156.12 001246506.1_39724001_3 - 0.056 13.1 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 IncA protein Connexin PF00029.17 001246506.1_39724001_3 - 0.087 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.17 001246506.1_39724001_3 - 0.13 10.0 0.3 0.19 9.5 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nop14 PF04147.10 001246506.1_39724001_3 - 0.38 8.8 21.0 0.5 8.4 21.0 1.0 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.11 001246506.1_39724001_3 - 2.5 6.7 6.9 3.5 6.2 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mito_fiss_reg PF05308.9 001246545.1_39724001_2 - 6.1e-68 229.4 0.3 9.3e-68 228.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator Hormone_2 PF00123.18 001194943.1_39722001_1 - 1.3e-26 92.0 2.1 2.7e-12 46.3 0.2 2.4 2 0 0 2 2 2 2 Peptide hormone KASH_CCD PF14662.4 001279856.1_39725001_2 - 2.3e-42 144.9 19.8 2.3e-26 92.7 12.1 2.2 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH EF-hand_9 PF14658.4 001279856.1_39725001_2 - 7.7e-27 93.3 0.0 1.4e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain DUF342 PF03961.11 001279856.1_39725001_2 - 0.091 11.2 4.7 0.13 10.7 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HOOK PF05622.10 001279856.1_39725001_2 - 0.18 9.8 13.1 0.27 9.2 13.1 1.2 1 0 0 1 1 1 0 HOOK protein Atg14 PF10186.7 001279856.1_39725001_2 - 0.27 10.2 6.9 0.41 9.5 6.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XRCC4 PF06632.10 001279856.1_39725001_2 - 0.33 9.6 10.4 0.1 11.3 6.1 1.9 1 1 1 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Leu_zip PF15294.4 001279856.1_39725001_2 - 0.64 9.3 10.7 1.3 8.4 10.7 1.4 1 1 0 1 1 1 0 Leucine zipper ZapB PF06005.10 001279856.1_39725001_2 - 0.77 10.1 20.5 9.3 6.6 1.0 3.4 1 1 2 3 3 3 0 Cell division protein ZapB THOC7 PF05615.11 001279856.1_39725001_2 - 2.7 8.2 13.5 18 5.5 0.8 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 Cnn_1N PF07989.9 001279856.1_39725001_2 - 7.4 6.7 15.9 2.7 8.0 1.6 3.3 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Bcl-2_BAD PF10514.7 001251928.1_39722001_2 - 1.7e-91 304.9 15.0 2e-91 304.7 15.0 1.0 1 0 0 1 1 1 1 Pro-apoptotic Bcl-2 protein, BAD Bclx_interact PF08945.8 001251928.1_39722001_2 - 0.00061 19.4 0.1 0.0014 18.2 0.1 1.7 1 0 0 1 1 1 1 Bcl-x interacting, BH3 domain BAF PF02961.12 001246653.1_39722001_1 - 1.3e-33 115.1 0.1 2.3e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Barrier to autointegration factor SR-25 PF10500.7 001246653.1_39722001_2 - 2.4 7.6 22.4 3.8 6.9 22.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1418 PF07214.10 001246653.1_39722001_3 - 0.25 11.1 1.0 1.4 8.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) HIG_1_N PF04588.11 001329985.1_39724001_2 - 3.3e-16 59.1 1.2 5.5e-16 58.4 1.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Pro_isomerase PF00160.19 001246436.1_39724001_2 - 6.8e-50 169.3 0.0 9.8e-50 168.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Piwi PF02171.15 001289638.1_39726001_1 - 2e-87 293.1 0.1 3e-87 292.5 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.20 001289638.1_39726001_1 - 1e-33 116.0 0.4 1.7e-33 115.2 0.4 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.8 001289638.1_39726001_1 - 4.7e-09 35.6 0.0 1.4e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.3 001289638.1_39726001_1 - 0.0036 17.9 0.0 0.0076 16.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute Hormone_recep PF00104.28 001280303.1_39725001_3 - 1.7e-39 135.4 3.0 1.7e-39 135.4 3.0 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.16 001280303.1_39725001_3 - 6.2e-31 106.5 15.3 6.2e-31 106.5 15.3 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) XS PF03468.12 001280303.1_39725001_3 - 0.18 11.9 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 XS domain Orn_Arg_deC_N PF02784.14 001280403.2_39726001_2 - 6.8e-64 215.5 0.1 8.6e-64 215.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.20 001280403.2_39726001_2 - 1.5e-24 86.1 0.0 2.8e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain La PF05383.15 001246577.1_39725001_2 - 9.7e-21 73.5 0.2 1.8e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 La domain SUZ-C PF12901.5 001246577.1_39725001_2 - 2e-07 30.7 0.1 3.9e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.20 001246577.1_39725001_2 - 0.034 13.8 0.1 9.8 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.4 001328171.1_39729001_2 - 3.1e-58 191.6 73.0 1.5e-08 34.6 0.2 12.3 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2 PF00096.24 001328171.1_39729001_2 - 1.1e-40 135.7 75.5 1.1e-06 28.6 0.3 11.5 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001328171.1_39729001_2 - 4.8e-23 79.7 70.2 0.00096 19.7 1.1 11.7 11 0 0 11 11 11 9 C2H2-type zinc finger KRAB PF01352.25 001328171.1_39729001_2 - 1.4e-21 75.8 2.3 2.5e-21 74.9 2.3 1.4 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 001328171.1_39729001_2 - 4.1e-09 36.4 38.6 0.92 9.8 0.0 9.6 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001328171.1_39729001_2 - 5e-07 29.4 52.8 0.01 15.7 2.5 9.8 10 0 0 10 10 10 7 C2H2-type zinc finger Zn-ribbon_8 PF09723.8 001328171.1_39729001_2 - 2e-05 24.5 40.9 0.016 15.1 2.5 6.8 4 2 4 8 8 7 5 Zinc ribbon domain DZR PF12773.5 001328171.1_39729001_2 - 0.0025 17.7 34.5 0.72 9.8 0.1 5.6 2 1 1 3 3 3 2 Double zinc ribbon zinc_ribbon_15 PF17032.3 001328171.1_39729001_2 - 0.026 15.1 29.2 1.7 9.3 0.2 6.1 3 1 5 8 8 8 0 zinc-ribbon family Siva PF05458.10 001328171.1_39729001_2 - 5.8 6.4 17.1 3.5 7.1 0.3 3.6 1 1 2 3 3 3 0 Cd27 binding protein (Siva) GTP_EFTU PF00009.25 001279863.1_39727001_3 - 1.5e-63 213.7 0.0 2.3e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.16 001279863.1_39727001_3 - 1.3e-34 118.4 0.0 4.3e-34 116.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.4 001279863.1_39727001_3 - 4.4e-28 97.0 0.0 8.6e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.22 001279863.1_39727001_3 - 2.2e-24 85.2 0.0 7.2e-24 83.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.23 001279863.1_39727001_3 - 1.6e-16 60.3 0.0 4e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.3 001279863.1_39727001_3 - 3.1e-06 26.9 0.0 1.7e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.21 001279863.1_39727001_3 - 0.006 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.14 001279863.1_39727001_3 - 0.042 13.0 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AvrPtoB_bdg PF16847.3 001279863.1_39727001_3 - 0.056 13.8 0.0 0.49 10.8 0.0 2.4 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain Arm PF00514.21 001280407.1_39724001_2 - 1e-90 295.2 19.4 1.9e-13 49.8 0.2 9.2 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.3 001280407.1_39724001_2 - 1.5e-24 85.1 2.3 1.3e-22 78.9 3.0 2.5 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.4 001280407.1_39724001_2 - 3.4e-23 81.5 1.7 2.6e-09 37.2 0.1 6.0 5 1 1 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.4 001280407.1_39724001_2 - 7.5e-19 67.8 0.4 2.9e-06 27.5 0.0 6.3 2 2 4 7 7 7 5 HEAT repeats HEAT PF02985.20 001280407.1_39724001_2 - 3.4e-17 60.9 6.2 0.0038 17.2 0.0 7.2 8 0 0 8 8 8 3 HEAT repeat IBB PF01749.18 001280407.1_39724001_2 - 5.1e-17 61.9 2.1 1.2e-16 60.6 2.1 1.7 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.18 001280407.1_39724001_2 - 2.2e-07 29.7 1.5 2.3e-06 26.4 1.3 2.3 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.6 001280407.1_39724001_2 - 8.9e-07 28.9 0.7 0.097 12.7 0.1 4.3 4 1 1 5 5 5 3 V-ATPase subunit H Cnd1 PF12717.5 001280407.1_39724001_2 - 2.1e-06 27.7 1.2 0.039 13.8 0.1 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.12 001280407.1_39724001_2 - 8.4e-05 21.9 0.4 0.0042 16.3 0.4 2.5 1 1 0 1 1 1 1 V-ATPase subunit H Atx10homo_assoc PF09759.7 001280407.1_39724001_2 - 0.00015 21.6 1.2 0.21 11.5 0.0 4.4 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.11 001280407.1_39724001_2 - 0.00028 20.3 1.1 0.2 11.0 0.4 3.4 2 1 0 3 3 3 1 Armadillo-like DRIM PF07539.10 001280407.1_39724001_2 - 0.0065 14.7 0.5 0.93 7.6 0.0 2.3 1 1 1 2 2 2 2 Down-regulated in metastasis Mo25 PF08569.9 001280407.1_39724001_2 - 0.016 14.4 0.0 0.038 13.2 0.0 1.5 1 1 0 1 1 1 0 Mo25-like RasGEF_N_2 PF14663.4 001280407.1_39724001_2 - 0.054 13.7 0.3 16 5.8 0.0 3.7 3 2 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CTNNBL PF08216.9 001280407.1_39724001_2 - 0.22 11.6 4.0 8.1 6.5 0.1 3.6 4 1 0 4 4 3 0 Catenin-beta-like, Arm-motif containing nuclear NAD_binding_1 PF00175.19 001302418.1_39725001_2 - 6.7e-36 123.1 0.0 1.2e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.22 001302418.1_39725001_2 - 1.7e-35 121.2 0.0 2.5e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.10 001302418.1_39725001_2 - 9.3e-05 22.5 0.0 0.00039 20.5 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.9 001302418.1_39725001_2 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Kelch_5 PF13854.4 001280186.1_39726001_1 - 2e-38 129.6 1.0 2.1e-05 24.2 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.4 001280186.1_39726001_1 - 1.2e-33 114.6 6.1 4.7e-08 33.0 0.0 7.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.23 001280186.1_39726001_1 - 5.9e-29 99.3 5.5 1.6e-06 27.5 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.4 001280186.1_39726001_1 - 4.5e-23 80.8 0.9 0.0022 17.8 0.0 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.4 001280186.1_39726001_1 - 2e-21 75.3 1.5 0.011 15.8 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.13 001280186.1_39726001_1 - 6.2e-18 63.9 3.9 0.003 17.3 0.0 7.0 6 0 0 6 6 6 5 Kelch motif fn3 PF00041.19 001280186.1_39726001_1 - 7.1e-13 48.6 0.7 0.0012 19.0 0.0 4.4 4 0 0 4 4 4 3 Fibronectin type III domain SR-25 PF10500.7 001280186.1_39726001_3 - 0.71 9.3 22.7 1 8.8 22.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NYD-SP28 PF14772.4 001246546.1_39724001_3 - 3.9e-29 100.5 10.7 3.9e-29 100.5 10.7 4.9 4 2 1 5 5 5 1 Sperm tail Aph-1 PF06105.10 001280105.1_39725001_1 - 1.2e-92 309.4 14.0 1.5e-92 309.1 14.0 1.1 1 0 0 1 1 1 1 Aph-1 protein Peptidase_M3_N PF08439.8 001280105.1_39725001_1 - 0.099 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Oligopeptidase F Metallothio PF00131.18 001301279.1_39721001_1 - 2.3e-18 65.9 63.8 2.3e-18 65.9 63.8 1.7 2 0 0 2 2 2 1 Metallothionein C2-set PF05790.13 001193663.1_39723001_1 - 1.6e-16 60.1 1.9 3.2e-16 59.2 1.9 1.5 1 0 0 1 1 1 1 Immunoglobulin C2-set domain V-set PF07686.15 001193663.1_39723001_1 - 2.4e-10 40.4 0.2 6.8e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.4 001193663.1_39723001_1 - 5.3e-05 23.4 1.5 0.00013 22.1 0.4 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.4 001193663.1_39723001_1 - 0.0022 18.4 1.1 1.6 9.3 0.4 2.8 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001193663.1_39723001_1 - 0.003 17.5 4.9 0.13 12.2 0.6 3.4 1 1 1 2 2 2 2 Immunoglobulin I-set domain EphA2_TM PF14575.4 001193663.1_39723001_1 - 0.03 15.0 0.0 0.065 13.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.10 001193663.1_39723001_1 - 0.055 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SARAF PF06682.10 001193663.1_39723001_1 - 0.063 12.8 3.5 0.092 12.3 2.0 1.9 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis YjgP_YjgQ PF03739.12 001193663.1_39723001_1 - 0.11 11.2 0.4 0.27 9.9 0.3 1.6 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family GAGA PF09237.9 001193663.1_39723001_3 - 0.72 9.6 4.6 0.37 10.5 2.3 1.7 2 0 0 2 2 2 0 GAGA factor Bax1-I PF01027.18 001280140.1_39724001_1 - 2.7e-30 105.6 23.7 3.6e-30 105.2 23.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF996 PF06195.11 001280140.1_39724001_1 - 1.8 8.7 13.7 4.6 7.4 13.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF996) TMEM100 PF16311.3 001280140.1_39724001_1 - 5.4 6.5 5.5 9.5 5.7 5.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 GETHR PF05671.9 001280140.1_39724001_2 - 0.44 9.8 2.9 1.8 7.9 1.1 2.5 1 1 1 2 2 2 0 GETHR pentapeptide repeat (5 copies) Zona_pellucida PF00100.21 001280070.1_39725001_3 - 3.4e-50 171.0 12.1 8.2e-50 169.8 12.1 1.7 1 0 0 1 1 1 1 Zona pellucida-like domain CUB PF00431.18 001280070.1_39725001_3 - 7.7e-41 138.8 0.6 8e-28 96.8 0.1 2.6 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.18 001280070.1_39725001_3 - 0.0015 18.2 0.5 0.12 12.1 0.1 3.0 2 0 0 2 2 2 1 CUB-like domain Rhodanese PF00581.18 001280334.1_39725001_1 - 7.8e-09 35.9 0.0 1.9e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain M-inducer_phosp PF06617.11 001280334.1_39725001_1 - 1e-08 34.7 3.2 2.5e-07 30.1 0.2 2.2 2 0 0 2 2 2 2 M-phase inducer phosphatase Sel1 PF08238.10 001242594.2_39725001_2 - 2.5e-13 50.1 4.2 0.0011 19.4 0.1 4.6 4 0 0 4 4 4 4 Sel1 repeat adh_short PF00106.23 001199077.1_39729001_3 - 1.4e-34 119.2 0.5 1.9e-34 118.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001199077.1_39729001_3 - 5.8e-28 97.9 0.5 8.6e-28 97.3 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.15 001199077.1_39729001_3 - 1e-23 83.6 0.2 1.6e-23 82.9 0.2 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.8 001199077.1_39729001_3 - 0.00073 19.4 1.0 0.00092 19.0 0.1 1.5 2 0 0 2 2 2 1 KR domain Alkyl_sulf_C PF14864.4 001199077.1_39729001_3 - 0.0046 17.1 0.0 0.0074 16.4 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal tRNA-synt_1b PF00579.23 001280042.1_39725001_2 - 8.5e-21 74.4 0.0 1.7e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.18 001280042.1_39725001_2 - 2.3e-19 69.2 0.0 4.8e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 WHEP-TRS domain Cpn60_TCP1 PF00118.22 001246643.1_39724001_3 - 7.3e-163 542.6 9.8 8.4e-163 542.4 9.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRR_9 PF14580.4 001279839.1_39725001_2 - 4e-15 55.6 6.8 4e-15 55.6 6.8 3.3 2 2 2 4 4 4 2 Leucine-rich repeat LRR_4 PF12799.5 001279839.1_39725001_2 - 5.3e-15 55.1 18.4 4.8e-06 26.7 4.3 4.2 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.4 001279839.1_39725001_2 - 2.3e-09 36.8 32.9 1.3e-06 27.9 8.2 3.4 1 1 3 4 4 4 4 Leucine rich repeat SWI-SNF_Ssr4 PF08549.8 001279839.1_39725001_2 - 0.51 8.8 4.0 0.83 8.1 4.0 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ECM1 PF05782.9 001246589.1_39724001_3 - 0 1034.6 40.5 0 1030.9 40.5 1.9 1 1 0 1 1 1 1 Extracellular matrix protein 1 (ECM1) Serum_albumin PF00273.18 001246589.1_39724001_3 - 6.7e-07 29.1 31.5 0.0031 17.2 5.7 3.9 2 1 1 4 4 4 4 Serum albumin family p31comet PF06581.10 001280256.1_39724001_2 - 5.3e-169 559.9 0.4 6.8e-169 559.6 0.4 1.1 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding ESCRT-II PF05871.10 001252014.2_39723001_2 - 6.9e-55 184.9 0.3 9.3e-55 184.5 0.3 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Gaa1 PF04114.12 001280127.1_39725001_1 - 4.8e-150 500.6 0.7 6.6e-150 500.2 0.7 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component C2-set_2 PF08205.10 001279805.1_39725001_2 - 7.9e-18 64.2 0.2 5e-15 55.2 0.1 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.4 001279805.1_39725001_2 - 2.3e-06 28.0 0.0 0.00085 19.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001279805.1_39725001_2 - 0.0021 17.9 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Nup88 PF10168.7 001280088.1_39725001_1 - 0 1027.4 0.0 0 1027.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore component CK2S PF15011.4 001280088.1_39725001_1 - 0.039 13.7 0.0 0.039 13.7 0.0 2.7 2 1 1 3 3 3 0 Casein Kinase 2 substrate FliJ PF02050.14 001280088.1_39725001_1 - 1.1 9.3 16.9 0.095 12.8 6.8 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein SRPRB PF09439.8 001280220.1_39724001_2 - 3.8e-73 244.7 0.2 5.5e-73 244.1 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.19 001280220.1_39724001_2 - 5.3e-14 51.9 0.0 1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001280220.1_39724001_2 - 3e-07 30.4 0.0 4.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001280220.1_39724001_2 - 2.2e-05 24.0 0.0 0.00052 19.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.16 001280220.1_39724001_2 - 0.00019 20.8 0.1 0.00043 19.7 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.11 001280220.1_39724001_2 - 0.00068 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.10 001280220.1_39724001_2 - 0.0017 17.6 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.18 001280220.1_39724001_2 - 0.0018 17.4 0.3 0.026 13.6 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit TIP49 PF06068.11 001280220.1_39724001_2 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Thymidylat_synt PF00303.17 001246582.1_39724001_3 - 4.6e-117 389.8 0.0 5.5e-117 389.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase TMEM40 PF15817.3 001280299.1_39724001_1 - 9.1e-74 244.7 0.1 1.4e-73 244.1 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 40 family SR-25 PF10500.7 001280299.1_39724001_1 - 0.0088 15.5 16.4 0.014 14.9 16.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.13 001280299.1_39724001_1 - 0.016 15.9 7.1 0.028 15.1 7.1 1.4 1 0 0 1 1 1 0 Chorion family 2 SPX PF03105.17 001280299.1_39724001_1 - 0.14 11.9 9.1 0.2 11.4 9.1 1.1 1 0 0 1 1 1 0 SPX domain PAP1 PF08601.8 001280299.1_39724001_1 - 1.3 8.6 10.7 1.8 8.1 10.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.7 001280299.1_39724001_1 - 1.8 6.9 3.8 2.4 6.5 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.7 001280299.1_39724001_1 - 9.5 4.8 7.1 13 4.4 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Perilipin PF03036.14 001280227.1_39724001_1 - 3.9e-162 539.7 13.4 4.6e-162 539.4 13.4 1.0 1 0 0 1 1 1 1 Perilipin family SH3BP5 PF05276.12 001280227.1_39724001_1 - 0.0037 17.0 1.4 0.0091 15.7 0.6 2.0 2 0 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) Apolipoprotein PF01442.16 001280227.1_39724001_1 - 0.052 13.3 3.7 1 9.1 0.1 2.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain FliJ PF02050.14 001280227.1_39724001_1 - 0.56 10.3 7.3 5.9 7.0 2.8 2.8 2 1 0 2 2 2 0 Flagellar FliJ protein DUF1664 PF07889.10 001280227.1_39724001_1 - 0.71 9.7 7.2 7.5 6.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.9 001280227.1_39724001_1 - 0.81 10.2 4.4 1.7 9.1 1.5 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HSP9_HSP12 PF04119.10 001280227.1_39724001_1 - 0.82 10.0 6.3 6.3 7.1 0.1 3.6 3 1 1 4 4 4 0 Heat shock protein 9/12 YtxH PF12732.5 001280227.1_39724001_1 - 0.97 9.9 5.0 15 6.1 0.3 3.7 3 1 0 3 3 3 0 YtxH-like protein IQ PF00612.25 001278051.1_39722001_3 - 3.8e-11 41.6 24.2 3.4e-06 26.2 1.0 4.4 4 0 0 4 4 4 3 IQ calmodulin-binding motif IMS PF00817.18 001279810.1_39726001_1 - 3.5e-45 153.5 0.0 5.6e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.6 001279810.1_39726001_1 - 6.8e-12 46.0 0.0 2e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Cdd1 PF11731.6 001279810.1_39726001_1 - 1.8e-05 24.8 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus IMS_HHH PF11798.6 001279810.1_39726001_1 - 5.3e-05 23.2 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF4414 PF14377.4 001279810.1_39726001_1 - 0.00012 22.2 0.1 0.44 10.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) HHH_5 PF14520.4 001279810.1_39726001_1 - 0.026 15.0 0.0 0.064 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF4332 PF14229.4 001279810.1_39726001_1 - 0.027 14.6 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DNA_pol_lambd_f PF10391.7 001279810.1_39726001_1 - 0.027 14.2 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda TfoX_C PF04994.11 001279810.1_39726001_1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 TfoX C-terminal domain RecG_wedge PF17191.2 001279810.1_39726001_1 - 0.046 13.2 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 RecG wedge domain ABA_GPCR PF12430.6 001280528.1_39724001_3 - 4.2e-41 140.6 11.8 4.2e-41 140.6 11.8 2.1 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.6 001280528.1_39724001_3 - 1.2e-28 98.9 0.4 2.8e-28 97.7 0.1 1.8 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal NPCC PF08058.9 001280528.1_39724001_3 - 9.7 6.1 16.6 0.69 9.8 0.1 3.4 3 0 0 3 3 3 0 Nuclear pore complex component Na_H_Exchanger PF00999.19 001280193.1_39724001_2 - 2.2e-29 102.3 33.4 3.1e-29 101.8 33.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Trypsin PF00089.24 001280253.1_39724001_1 - 7.5e-08 32.3 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.24 001280253.1_39724001_2 - 7.3e-17 61.8 0.0 1.1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin F-box-like PF12937.5 001160295.2_39729001_2 - 3e-09 36.5 1.8 6.6e-09 35.4 1.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001160295.2_39729001_2 - 2.5e-07 30.3 2.1 5.5e-07 29.2 2.1 1.6 1 0 0 1 1 1 1 F-box domain MIT PF04212.16 001160295.2_39729001_2 - 0.0013 18.6 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.26 001160295.2_39729001_2 - 0.16 11.7 0.1 0.33 10.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.15 001160295.2_39729001_2 - 0.16 12.0 0.7 0.7 10.0 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat SERTA PF06031.11 001320163.1_39726001_3 - 4.2e-17 61.4 2.3 8e-17 60.5 2.3 1.5 1 0 0 1 1 1 1 SERTA motif KOG2701 PF09762.7 001246416.1_39725001_1 - 1.4e-77 259.8 0.0 1.4e-77 259.8 0.0 3.8 3 2 0 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) DUF4107 PF13389.4 001246416.1_39725001_1 - 0.11 12.6 3.4 0.39 10.7 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF4107) DivIC PF04977.13 001246416.1_39725001_1 - 1 9.0 28.2 0.21 11.2 5.1 5.7 3 2 2 5 5 5 0 Septum formation initiator Baculo_PEP_C PF04513.10 001246416.1_39725001_1 - 1.4 8.8 6.0 5.2 7.0 4.8 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MitMem_reg PF13012.4 001246416.1_39725001_1 - 1.4 9.2 9.3 0.26 11.6 3.7 2.5 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF3573 PF12097.6 001246416.1_39725001_1 - 3.4 6.2 6.5 7.3 5.2 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Cir_Bir_Yir PF06022.9 001246416.1_39725001_1 - 5.9 6.2 15.2 0.059 12.7 2.4 2.9 2 1 1 3 3 3 0 Plasmodium variant antigen protein Cir/Yir/Bir p450 PF00067.20 001093774.1_39725001_2 - 2.2e-126 422.2 0.2 2.5e-126 422.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 GRAM PF02893.18 001280501.1_39724001_1 - 1.3e-14 53.8 0.0 2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.6 001280501.1_39724001_1 - 0.00054 20.0 0.0 0.00086 19.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 PITH PF06201.11 001280344.1_39724001_1 - 4e-40 137.4 0.0 5.3e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.18 001246452.1_39725001_1 - 5.1e-68 225.5 0.1 1.9e-33 114.4 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.4 001246452.1_39725001_1 - 7.6e-36 123.7 1.1 9.3e-28 97.3 2.4 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.4 001246452.1_39725001_1 - 7.7e-09 35.9 0.6 0.00082 19.7 0.1 3.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.4 001246452.1_39725001_1 - 1.1e-07 31.9 0.1 0.004 17.3 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.4 001246452.1_39725001_1 - 6e-06 26.2 0.0 0.031 14.3 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.19 001246452.1_39725001_1 - 0.00011 21.9 0.2 0.26 11.1 0.0 2.9 3 0 0 3 3 3 2 AhpC/TSA family OST3_OST6 PF04756.11 001246452.1_39725001_1 - 0.0003 20.1 0.0 0.53 9.4 0.0 2.6 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.4 001246452.1_39725001_1 - 0.0014 18.7 0.0 1.3 9.0 0.0 3.5 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.4 001246452.1_39725001_1 - 0.046 13.6 0.0 0.96 9.4 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain Filament PF00038.19 001280441.1_39725001_1 - 3.8e-96 322.2 54.9 5.1e-96 321.8 54.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.17 001280441.1_39725001_1 - 3.9e-19 68.9 1.0 6.5e-19 68.2 0.5 1.6 2 0 0 2 2 2 1 Lamin Tail Domain Jnk-SapK_ap_N PF09744.7 001280441.1_39725001_1 - 0.0081 16.3 5.7 0.0081 16.3 5.7 4.3 2 1 2 4 4 4 1 JNK_SAPK-associated protein-1 Spc7 PF08317.9 001280441.1_39725001_1 - 0.02 13.7 50.7 0.069 11.9 21.1 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1136 PF06582.10 001280441.1_39725001_1 - 0.066 13.0 2.0 1.9 8.4 0.3 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) IncA PF04156.12 001280441.1_39725001_1 - 9.4 5.8 65.1 0.033 13.8 12.1 3.9 1 1 2 3 3 3 0 IncA protein DNA_pol_A_exo1 PF01612.18 001280455.1_39726001_2 - 1.4e-50 171.3 1.1 2.6e-50 170.4 1.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.10 001280455.1_39726001_2 - 9.3e-24 83.8 0.1 4.6e-23 81.6 0.0 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.21 001280455.1_39726001_2 - 3.2e-13 49.3 0.0 8.1e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Pilt PF15453.4 001280172.1_39726001_3 - 7.1e-72 242.7 31.2 2.4e-53 181.7 16.2 3.6 2 1 1 3 3 3 2 Protein incorporated later into Tight Junctions HMMR_N PF15905.3 001280172.1_39726001_3 - 0.002 17.5 12.2 0.0029 17.0 12.2 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal IncA PF04156.12 001280172.1_39726001_3 - 0.0096 15.6 12.2 0.02 14.6 12.2 1.5 1 0 0 1 1 1 1 IncA protein Spc7 PF08317.9 001280172.1_39726001_3 - 0.018 13.8 12.2 0.03 13.1 12.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1672 PF07901.9 001280172.1_39726001_3 - 0.057 12.6 0.5 0.082 12.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) DUF2064 PF09837.7 001280172.1_39726001_3 - 0.093 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) GAS PF13851.4 001280172.1_39726001_3 - 0.28 10.4 13.0 0.63 9.2 13.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Wtap PF17098.3 001280172.1_39726001_3 - 1.7 8.4 12.6 0.21 11.4 6.9 2.1 1 1 1 2 2 2 0 WTAP/Mum2p family Lebercilin PF15619.4 001280172.1_39726001_3 - 2.1 7.8 18.5 13 5.2 18.4 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.4 001280172.1_39726001_3 - 3.8 6.6 5.0 5.7 6.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.9 001280172.1_39726001_3 - 7.2 7.1 11.0 0.7 10.3 1.8 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RRM_1 PF00076.20 001246442.2_39724001_3 - 6e-13 48.3 0.1 1.2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001246442.2_39724001_3 - 0.067 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APG6 PF04111.10 001246442.2_39724001_3 - 0.26 10.5 7.1 0.36 10.0 7.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 RP-C_C PF11800.6 001246442.2_39724001_3 - 0.31 10.9 4.1 0.49 10.3 4.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SURF2 PF05477.9 001246442.2_39724001_3 - 0.61 9.4 13.8 0.94 8.8 13.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) XhlA PF10779.7 001246442.2_39724001_3 - 0.86 9.7 5.4 1.8 8.7 5.4 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Nup88 PF10168.7 001246442.2_39724001_3 - 0.97 7.0 7.7 1.4 6.5 7.7 1.1 1 0 0 1 1 1 0 Nuclear pore component IncA PF04156.12 001246442.2_39724001_3 - 1 9.0 5.2 1.7 8.2 5.2 1.3 1 0 0 1 1 1 0 IncA protein TMPIT PF07851.11 001246442.2_39724001_3 - 3.1 6.8 6.0 5 6.1 6.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF972 PF06156.11 001246442.2_39724001_3 - 3.7 8.1 7.0 6.9 7.2 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) PIEZO PF15917.3 001246442.2_39724001_3 - 7.6 5.8 8.3 12 5.1 8.3 1.3 1 0 0 1 1 1 0 Piezo UQ_con PF00179.24 001246525.1_39724001_2 - 5e-45 152.4 0.0 6.6e-45 152.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.29 001246525.1_39724001_2 - 2.9e-10 39.7 0.0 5.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.4 001246525.1_39724001_2 - 3.6e-05 23.3 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.20 001246525.1_39724001_2 - 0.018 15.2 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain PDEase_I PF00233.17 001279932.1_39725001_3 - 2.3e-81 272.9 4.8 3.8e-81 272.2 4.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.10 001279932.1_39725001_3 - 4.8e-32 109.5 0.1 9.1e-32 108.6 0.1 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal LSR PF05624.12 001256590.1_39725001_3 - 2.2e-23 81.9 37.4 4.4e-23 80.9 37.4 1.5 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.15 001256590.1_39725001_3 - 0.00018 21.5 0.4 0.0032 17.5 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001256590.1_39725001_3 - 0.028 14.9 1.9 1 9.9 1.9 2.5 1 1 0 1 1 1 0 Immunoglobulin domain ig PF00047.23 001256590.1_39725001_3 - 0.072 13.1 0.2 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Sec7 PF01369.18 001251861.1_39729001_3 - 6e-66 221.5 0.1 7.9e-66 221.1 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain PH PF00169.27 001251861.1_39729001_3 - 6.4e-28 97.2 0.1 1.1e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.4 001251861.1_39729001_3 - 0.0005 20.3 0.1 0.0011 19.2 0.1 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain Tubulin PF00091.23 001280247.1_39724001_1 - 3.7e-67 226.2 0.0 4.9e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001280247.1_39724001_1 - 3.2e-51 172.7 0.0 4.9e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001280247.1_39724001_1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain DnaJ PF00226.29 001279783.1_39724001_1 - 1.7e-16 60.0 1.2 3.7e-16 58.9 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain HSP90 PF00183.16 001280457.1_39726001_1 - 2.6e-240 798.5 26.0 3.5e-240 798.1 26.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.24 001280457.1_39726001_1 - 1.8e-13 50.9 0.0 3.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.4 001280457.1_39726001_1 - 3.1e-10 39.9 0.1 8.4e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.12 001280457.1_39726001_1 - 8.4 4.4 14.0 15 3.6 14.0 1.3 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.20 001280408.1_39724001_2 - 5.1e-125 417.7 0.1 5.9e-125 417.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 MOEP19 PF16005.3 001243863.1_39723001_3 - 4e-35 119.5 0.4 7.5e-35 118.7 0.1 1.6 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_1 PF00013.27 001243863.1_39723001_3 - 0.018 14.7 0.9 0.049 13.3 0.0 2.1 2 0 0 2 2 2 0 KH domain WD40 PF00400.30 001280230.1_39725001_3 - 4.8e-34 115.7 16.9 1.3e-07 32.1 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280230.1_39725001_3 - 5.1e-13 49.0 0.3 0.014 15.6 0.0 6.3 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain SOCS_box PF07525.14 001280230.1_39725001_3 - 2.9e-10 40.2 2.3 3.3e-10 40.0 0.5 2.0 2 0 0 2 2 2 1 SOCS box Ge1_WD40 PF16529.3 001280230.1_39725001_3 - 2.4e-09 36.5 0.4 0.13 11.1 0.0 4.5 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.9 001280230.1_39725001_3 - 8.3e-05 22.4 0.0 0.12 12.1 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.4 001280230.1_39725001_3 - 0.0013 18.0 0.1 3.9 6.6 0.0 3.4 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.6 001280230.1_39725001_3 - 0.0097 14.4 0.3 0.13 10.7 0.1 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.10 001280230.1_39725001_3 - 0.2 11.5 6.1 18 5.3 0.2 4.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.4 001280230.1_39725001_3 - 0.24 11.8 2.7 3 8.3 0.2 3.4 4 0 0 4 4 4 0 PQQ-like domain HD PF01966.20 001280510.1_39724001_1 - 1.4e-18 67.1 0.0 4e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 HD domain SAM_2 PF07647.15 001280510.1_39724001_1 - 5.9e-10 39.0 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.28 001280510.1_39724001_1 - 1.6e-09 37.9 0.0 3.8e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.17 001280510.1_39724001_1 - 0.0085 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ste50p-SAM PF09235.8 001280510.1_39724001_1 - 0.078 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Ribosomal_L7Ae PF01248.24 001252509.1_39722001_2 - 4.8e-30 103.0 1.8 6e-30 102.7 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HAD PF12710.5 001252509.1_39722001_2 - 0.14 12.4 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase 7tm_1 PF00001.19 001280171.1_39725001_2 - 5e-45 153.7 30.2 1.6e-44 152.0 30.2 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) F-box PF00646.31 001248010.1_39725001_1 - 0.00018 21.2 0.0 0.00064 19.4 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.5 001248010.1_39725001_1 - 0.021 14.6 0.0 0.089 12.6 0.0 2.1 1 0 0 1 1 1 0 F-box-like SYCE1 PF15233.4 001280134.1_39723001_2 - 4.7e-67 224.6 22.8 4.7e-67 224.6 22.8 4.0 4 0 0 4 4 4 1 Synaptonemal complex central element protein 1 CENP-Q PF13094.4 001280134.1_39723001_2 - 0.01 15.9 4.6 0.01 15.9 4.6 4.1 4 1 0 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.10 001280134.1_39723001_2 - 0.065 12.5 0.8 0.085 12.1 0.4 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF745 PF05335.11 001280134.1_39723001_2 - 1.1 8.9 30.9 0.057 13.0 9.3 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF745) CTP_transf_like PF01467.24 001280130.1_39724001_2 - 2.1e-46 157.6 0.0 9.7e-31 106.8 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.10 001280130.1_39724001_2 - 0.00036 20.3 0.5 0.2 11.4 0.1 3.1 3 0 0 3 3 3 2 FAD synthetase ScdA_N PF04405.12 001280130.1_39724001_2 - 0.018 14.6 0.3 3.5 7.2 0.0 2.7 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) DUF218 PF02698.15 001280130.1_39724001_2 - 0.084 12.8 0.0 1 9.3 0.0 2.2 1 1 0 2 2 2 0 DUF218 domain UBX PF00789.18 001280321.1_39724001_2 - 3.5e-20 71.8 0.0 7.1e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.4 001280321.1_39724001_2 - 2.2e-15 56.5 0.1 3.8e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.4 001280321.1_39724001_2 - 3e-13 49.2 0.1 1.6e-11 43.7 0.0 2.5 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.18 001280321.1_39724001_2 - 0.036 13.8 3.5 0.11 12.3 3.5 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredox_DsbH PF03190.13 001280321.1_39724001_2 - 0.055 13.3 0.2 0.09 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Spt5_N PF11942.6 001280321.1_39724001_2 - 0.18 12.7 2.6 0.37 11.7 2.6 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal ApoL PF05461.9 001246409.1_39725001_2 - 2e-132 441.2 5.6 2.5e-132 440.9 5.6 1.1 1 0 0 1 1 1 1 Apolipoprotein L SseC PF04888.10 001246409.1_39725001_2 - 0.0019 17.6 0.7 0.005 16.2 0.1 1.7 1 1 1 2 2 2 1 Secretion system effector C (SseC) like family DUF3150 PF11348.6 001246409.1_39725001_2 - 0.044 12.9 0.4 0.17 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) Vir_act_alpha_C PF10400.7 001246409.1_39725001_2 - 0.2 12.2 2.9 0.61 10.7 0.1 2.6 2 1 0 2 2 2 0 Virulence activator alpha C-term OAD_gamma PF04277.11 001280169.1_39725001_1 - 8.6 6.9 7.3 13 6.3 7.3 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain WD40 PF00400.30 001280169.1_39725001_2 - 1e-15 57.7 11.7 0.0098 16.6 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001280169.1_39725001_2 - 3.3e-08 33.6 0.1 0.5 10.6 0.0 5.1 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.3 001280169.1_39725001_2 - 0.00084 18.3 1.2 0.21 10.4 0.1 3.7 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TIR PF01582.18 001130468.1_39725001_1 - 2.6e-26 92.4 1.0 4.3e-26 91.7 1.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.4 001130468.1_39725001_1 - 5.3e-21 74.0 29.8 7e-11 41.6 4.9 7.4 4 3 4 8 8 8 5 Leucine rich repeat LRR_4 PF12799.5 001130468.1_39725001_1 - 7.1e-18 64.2 36.1 5e-06 26.6 0.2 8.3 6 2 3 9 9 9 6 Leucine Rich repeats (2 copies) TIR_2 PF13676.4 001130468.1_39725001_1 - 9.7e-13 48.2 0.0 2.1e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.4 001130468.1_39725001_1 - 3.3e-07 29.7 21.9 0.44 10.6 0.1 10.4 12 0 0 12 12 12 3 Leucine Rich repeat LRR_9 PF14580.4 001130468.1_39725001_1 - 1.1e-06 28.1 8.1 0.0038 16.6 0.6 4.0 3 1 1 4 4 4 2 Leucine-rich repeat LRRCT PF01463.22 001130468.1_39725001_1 - 5.1e-06 26.5 0.0 2.1e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.31 001130468.1_39725001_1 - 0.00068 19.6 33.2 0.79 10.3 0.3 11.1 9 3 1 10 10 10 2 Leucine Rich Repeat TIR-like PF10137.7 001130468.1_39725001_1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain GST_N PF02798.18 001246568.1_39722001_3 - 2e-22 79.2 0.0 3.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001246568.1_39722001_3 - 3.3e-19 68.8 0.1 6.6e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.4 001246568.1_39722001_3 - 1.6e-17 63.4 0.2 3.2e-17 62.4 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001246568.1_39722001_3 - 0.15 11.7 3.1 0.23 11.1 0.7 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MBD PF01429.17 001280474.1_39725001_1 - 1e-20 73.1 0.0 3e-20 71.6 0.0 1.9 1 0 0 1 1 1 1 Methyl-CpG binding domain HhH-GPD PF00730.23 001280474.1_39725001_1 - 0.00044 20.5 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Tim17 PF02466.17 001243911.1_39724001_1 - 2.6e-14 53.3 4.3 4.1e-14 52.7 4.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Rick_17kDa_Anti PF05433.13 001243911.1_39724001_1 - 0.82 9.5 8.0 1.5 8.6 8.0 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain zf-tcix PF14952.4 001280246.1_39726001_2 - 2.8e-20 71.5 7.3 6.2e-20 70.4 7.3 1.6 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.7 001280246.1_39726001_2 - 0.011 15.1 2.0 0.03 13.6 2.0 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com B56 PF01603.18 001280086.1_39724001_3 - 9.1e-200 663.8 10.2 1.1e-199 663.5 10.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.5 001280086.1_39724001_3 - 0.21 11.4 2.2 3.7 7.4 0.3 2.8 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Requiem_N PF14051.4 001246651.1_39725001_3 - 3.5e-36 123.1 1.3 5.8e-36 122.4 1.3 1.4 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.27 001246651.1_39725001_3 - 8.8e-19 67.0 25.8 5.1e-11 42.1 7.6 3.5 3 1 1 4 4 4 2 PHD-finger PHD_4 PF16866.3 001246651.1_39725001_3 - 0.013 15.5 7.7 0.013 15.5 7.7 3.0 2 1 1 3 3 3 0 PHD-finger zf-C2H2_4 PF13894.4 001246651.1_39725001_3 - 0.052 14.3 0.7 0.052 14.3 0.7 4.4 4 1 1 5 5 5 0 C2H2-type zinc finger Lar_restr_allev PF14354.4 001246651.1_39725001_3 - 7.4 6.9 20.4 5.5e+02 0.9 0.1 3.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar DSPc PF00782.18 001160051.1_39723001_3 - 5.7e-33 113.4 0.0 7.5e-33 113.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.25 001160051.1_39723001_3 - 0.00064 19.2 1.0 0.00096 18.6 0.1 1.6 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.4 001160051.1_39723001_3 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Peptidase_M16 PF00675.18 001280470.1_39725001_1 - 3e-43 147.2 0.0 5.2e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.19 001280470.1_39725001_1 - 7.4e-42 143.3 0.0 1.5e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2695 PF10905.6 001280470.1_39725001_1 - 0.017 15.2 0.0 0.062 13.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) ThiF PF00899.19 001246619.1_39725001_1 - 3.8e-48 163.9 0.0 5.2e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family zf-H2C2_2 PF13465.4 001246644.1_39725001_1 - 2.4e-137 441.7 148.8 8.4e-09 35.4 1.2 19.5 20 0 0 20 20 19 19 Zinc-finger double domain zf-C2H2 PF00096.24 001246644.1_39725001_1 - 1.1e-93 302.7 152.3 1.4e-06 28.3 1.4 19.4 19 0 0 19 19 19 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001246644.1_39725001_1 - 1.2e-48 159.4 151.9 0.00054 20.4 1.2 18.8 19 0 0 19 19 19 17 C2H2-type zinc finger zf-C2H2_jaz PF12171.6 001246644.1_39725001_1 - 2.3e-28 97.7 81.8 0.027 14.7 0.3 17.6 18 0 0 18 18 17 12 Zinc-finger double-stranded RNA-binding KRAB PF01352.25 001246644.1_39725001_1 - 1e-21 76.2 0.2 2e-21 75.2 0.2 1.5 1 0 0 1 1 1 1 KRAB box zf-met PF12874.5 001246644.1_39725001_1 - 7.4e-15 54.7 129.7 0.022 15.0 1.3 17.7 18 0 0 18 18 18 11 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.8 001246644.1_39725001_1 - 6.4e-14 51.7 104.5 0.042 13.8 2.6 13.4 5 3 12 17 17 17 13 Zinc ribbon domain zf-C2H2_6 PF13912.4 001246644.1_39725001_1 - 8.7e-13 47.8 119.0 0.032 14.1 0.6 18.5 19 0 0 19 19 19 11 C2H2-type zinc finger XPA_N PF01286.16 001246644.1_39725001_1 - 1.3e-09 37.8 88.6 1.8 8.5 0.4 18.1 18 0 0 18 18 18 6 XPA protein N-terminal zf-trcl PF13451.4 001246644.1_39725001_1 - 1.9e-06 27.5 89.4 0.018 14.8 1.2 15.8 13 5 1 14 14 14 3 Probable zinc-ribbon domain C1_1 PF00130.20 001246644.1_39725001_1 - 4.4e-05 23.2 90.9 0.68 9.7 2.0 14.0 1 1 14 15 15 15 6 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.12 001246644.1_39725001_1 - 9.9e-05 22.2 73.0 0.18 11.7 1.2 11.5 7 3 3 10 10 10 6 Adenylate kinase, active site lid BolA PF01722.16 001246644.1_39725001_1 - 0.0061 16.7 32.4 0.79 9.9 1.0 8.0 5 2 4 9 9 9 2 BolA-like protein DUF3268 PF11672.6 001246644.1_39725001_1 - 0.36 11.0 76.9 0.25 11.6 1.9 9.5 5 2 6 13 13 12 0 zinc-finger-containing domain zinc_ribbon_15 PF17032.3 001246644.1_39725001_1 - 0.45 11.2 81.7 1.6 9.4 1.3 9.7 1 1 9 10 10 10 0 zinc-ribbon family GAGA PF09237.9 001246644.1_39725001_1 - 0.51 10.0 0.0 0.51 10.0 0.0 6.1 4 2 3 8 8 8 0 GAGA factor PMT PF02366.16 001246645.1_39727001_3 - 9.9e-97 323.2 23.4 9.9e-97 323.2 23.4 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.3 001246645.1_39727001_3 - 2.9e-51 173.8 8.4 2.9e-51 173.8 8.4 2.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.17 001246645.1_39727001_3 - 1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 MIR domain Solute_trans_a PF03619.14 001251859.1_39728001_3 - 4.4e-91 304.9 20.7 5.8e-91 304.6 20.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Integrin_beta PF00362.16 001034122.1_39725001_3 - 3e-116 387.3 0.0 4.3e-116 386.8 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.9 001034122.1_39725001_3 - 2.1e-16 59.2 0.5 3.7e-16 58.4 0.5 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.10 001034122.1_39725001_3 - 3.9e-16 59.2 2.4 3.9e-16 59.2 2.4 3.7 4 1 0 4 4 4 1 Integrin beta tail domain PSI_integrin PF17205.1 001034122.1_39725001_3 - 9.7e-13 47.6 6.5 9.7e-13 47.6 6.5 4.5 4 0 0 4 4 4 1 Integrin plexin domain EGF_2 PF07974.11 001034122.1_39725001_3 - 0.0083 16.3 11.4 0.0083 16.3 11.4 7.4 5 3 3 8 8 8 4 EGF-like domain CCDC92 PF14916.4 001279803.1_39724001_2 - 5e-24 83.7 9.3 6.1e-23 80.2 3.0 2.5 2 0 0 2 2 2 2 Coiled-coil domain of unknown function Exonuc_VII_L PF02601.13 001279803.1_39724001_2 - 0.15 11.4 8.1 0.23 10.8 8.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.10 001279803.1_39724001_2 - 0.24 10.6 17.9 0.36 10.0 17.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.4 001279803.1_39724001_2 - 0.52 9.5 7.6 0.84 8.8 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.6 001279803.1_39724001_2 - 0.89 6.9 14.2 1.2 6.5 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NYD-SP28 PF14772.4 001279803.1_39724001_2 - 1.7 8.6 14.1 1.2 9.1 10.6 2.1 1 1 1 2 2 2 0 Sperm tail Atg14 PF10186.7 001279803.1_39724001_2 - 3.7 6.4 18.6 1.7 7.5 15.4 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.13 001279803.1_39724001_2 - 5.3 7.3 17.0 6.4 7.0 15.1 1.8 1 1 0 1 1 1 0 Fez1 IncA PF04156.12 001279803.1_39724001_2 - 5.8 6.5 24.5 9 5.9 16.8 2.7 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.10 001279803.1_39724001_2 - 6.2 6.0 7.5 9.4 5.4 5.7 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FlxA PF14282.4 001279803.1_39724001_2 - 7.6 6.5 14.8 2.1 8.2 5.0 3.1 1 1 1 3 3 3 0 FlxA-like protein DUF4618 PF15397.4 001279803.1_39724001_2 - 7.7 5.7 22.2 1.8 7.8 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Leo1 PF04004.11 001246443.2_39725001_3 - 8.6e-56 188.2 8.6 2.2e-55 186.9 0.0 3.3 2 1 0 2 2 2 1 Leo1-like protein Cpn60_TCP1 PF00118.22 001246520.1_39725001_2 - 1.6e-169 564.5 6.3 1.9e-169 564.3 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1308 PF07000.9 001246520.1_39725001_2 - 0.012 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) DUF1180 PF06679.10 001251937.2_39726001_2 - 3.2e-38 131.6 0.1 5.3e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) CcmD PF04995.12 001251937.2_39726001_2 - 0.48 10.4 5.2 0.11 12.4 0.9 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Herpes_capsid PF06112.9 001251937.2_39726001_2 - 0.91 9.4 4.2 1.6 8.6 4.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PRT_C PF08372.8 001251937.2_39726001_2 - 4 7.0 4.9 2.7 7.6 2.1 1.9 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal MASE4 PF17158.2 001251937.2_39726001_2 - 7.4 5.6 9.2 29 3.6 4.6 2.7 3 0 0 3 3 3 0 Membrane-associated sensor, integral membrane domain CD225 PF04505.10 001198769.1_39722001_1 - 7.8e-26 89.9 0.0 1.5e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF3708 PF12501.6 001198769.1_39722001_1 - 0.066 12.9 0.3 0.096 12.3 0.3 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter WD40 PF00400.30 001246362.1_39724001_3 - 2e-30 104.2 8.1 2.8e-06 27.8 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat CSTF1_dimer PF16699.3 001246362.1_39724001_3 - 3.6e-24 84.2 0.3 6.1e-24 83.4 0.3 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.5 001246362.1_39724001_3 - 1.7e-11 44.1 0.0 0.019 15.1 0.0 4.6 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.6 001246362.1_39724001_3 - 9.9e-06 24.0 0.1 0.00018 19.9 0.0 2.1 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.3 001246362.1_39724001_3 - 0.0035 16.2 0.6 0.81 8.5 0.1 2.8 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PP2C PF00481.19 001246550.1_39725001_1 - 3.4e-90 302.0 0.0 4.7e-90 301.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.4 001246550.1_39725001_1 - 0.011 15.3 0.0 0.071 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C DUF4505 PF14956.4 001246478.1_39724001_3 - 6.4e-79 263.8 0.0 8.1e-79 263.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) NOT2_3_5 PF04153.16 001280492.1_39724001_1 - 6.5e-31 107.0 0.2 1.3e-30 106.1 0.2 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Serpin PF00079.18 001246610.1_39725001_3 - 8.9e-94 314.7 0.0 1e-93 314.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Tmp39 PF10271.7 001246435.1_39724001_3 - 2.4e-195 649.5 20.3 2.7e-195 649.3 20.3 1.0 1 0 0 1 1 1 1 Putative transmembrane protein EF_assoc_1 PF08355.10 001246435.1_39724001_3 - 0.13 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 EF hand associated zf-C2H2 PF00096.24 001280131.1_39725001_3 - 2.8e-28 96.6 37.9 8.1e-05 22.7 1.3 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.4 001280131.1_39725001_3 - 2e-27 94.3 43.5 7e-08 32.5 0.4 7.4 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.4 001280131.1_39725001_3 - 5.6e-18 63.9 34.7 0.0071 17.0 0.8 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_8 PF15909.3 001280131.1_39725001_3 - 2.6e-09 37.2 19.8 0.0019 18.3 1.9 4.0 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.6 001280131.1_39725001_3 - 1.2e-05 25.4 15.7 0.061 13.5 1.8 6.0 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding Marek_A PF02124.13 001280131.1_39725001_3 - 0.00036 20.3 1.6 0.63 9.7 0.3 2.8 2 1 1 3 3 3 2 Marek's disease glycoprotein A zf-C2H2_6 PF13912.4 001280131.1_39725001_3 - 0.00055 19.7 27.0 0.04 13.8 0.7 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.3 001280131.1_39725001_3 - 0.22 11.5 18.3 3.5 7.6 0.2 5.0 1 1 4 5 5 5 0 Aberrant zinc-finger TMEM101 PF15111.4 001246445.1_39724001_3 - 2.6e-116 387.4 4.7 3.2e-116 387.1 4.7 1.1 1 0 0 1 1 1 1 TMEM101 protein family DoxX PF07681.10 001246445.1_39724001_3 - 4.9 7.7 9.5 2.5 8.6 0.1 2.8 2 1 0 2 2 2 0 DoxX NYD-SP28 PF14772.4 001246462.1_39726001_1 - 5.5e-30 103.3 16.1 5.5e-30 103.3 16.1 5.7 6 0 0 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.4 001246462.1_39726001_1 - 5.6e-23 80.7 7.6 5.6e-23 80.7 7.6 5.1 4 1 2 6 6 6 1 Sperm tail C-terminal domain DUF3653 PF12375.6 001246462.1_39726001_1 - 0.13 12.3 1.2 1 9.4 0.0 2.9 2 0 0 2 2 2 0 Phage protein Octopine_DH PF02317.15 001246462.1_39726001_1 - 1.4 8.9 8.9 0.39 10.7 1.5 2.8 1 1 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain LRR19-TM PF15176.4 001246462.1_39726001_1 - 1.8 8.4 8.0 11 5.9 0.4 3.4 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain RVT_3 PF13456.4 001246462.1_39726001_1 - 6.1 6.4 8.7 0.4 10.3 0.2 3.1 3 0 0 3 3 3 0 Reverse transcriptase-like GvpK PF05121.10 001246462.1_39726001_1 - 8 6.5 19.5 0.72 9.8 1.4 4.6 4 1 0 4 4 4 0 Gas vesicle protein K TIP49 PF06068.11 001280445.1_39724001_1 - 3.3e-183 609.0 3.5 4e-183 608.7 3.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.27 001280445.1_39724001_1 - 3.6e-09 37.0 0.5 1.7e-05 25.1 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.4 001280445.1_39724001_1 - 1.9e-07 31.5 0.2 2.5e-06 27.9 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.10 001280445.1_39724001_1 - 3e-06 26.5 0.2 0.0013 17.9 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.12 001280445.1_39724001_1 - 1.1e-05 25.4 0.2 0.0027 17.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.13 001280445.1_39724001_1 - 2.4e-05 23.6 0.2 4.5e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.4 001280445.1_39724001_1 - 9.2e-05 22.6 0.4 0.15 12.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain Sigma54_activat PF00158.24 001280445.1_39724001_1 - 0.00035 20.2 0.4 0.19 11.3 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.19 001280445.1_39724001_1 - 0.00041 19.6 1.7 0.0083 15.4 0.4 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.4 001280445.1_39724001_1 - 0.001 19.3 5.0 0.0023 18.2 2.8 2.4 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.4 001280445.1_39724001_1 - 0.002 17.6 0.1 0.0087 15.5 0.1 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.11 001280445.1_39724001_1 - 0.0024 17.1 0.1 0.0052 16.0 0.1 1.5 1 0 0 1 1 1 1 KaiC Zeta_toxin PF06414.10 001280445.1_39724001_1 - 0.0056 15.9 0.4 0.012 14.8 0.4 1.4 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.7 001280445.1_39724001_1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.4 001280445.1_39724001_1 - 0.019 14.6 1.2 1 8.9 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.4 001280445.1_39724001_1 - 0.055 13.0 0.1 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.10 001280445.1_39724001_1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.14 001280445.1_39724001_1 - 0.083 12.2 1.8 0.37 10.1 0.4 2.5 2 0 0 2 2 2 0 PhoH-like protein MS_channel PF00924.16 001280445.1_39724001_1 - 0.086 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel AAA_28 PF13521.4 001280445.1_39724001_1 - 0.1 12.7 0.2 0.27 11.3 0.2 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.13 001280445.1_39724001_1 - 0.11 12.4 0.3 5 7.0 0.1 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.4 001280445.1_39724001_1 - 0.11 12.1 0.2 0.66 9.6 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.15 001280445.1_39724001_1 - 0.21 11.4 0.8 0.44 10.4 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_L35Ae PF01247.16 001251952.1_39721001_3 - 1.5e-47 159.6 0.4 1.8e-47 159.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.16 001251952.1_39721001_3 - 0.021 14.9 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain DUF2080 PF09853.7 001251952.1_39721001_3 - 0.096 12.3 0.2 0.36 10.5 0.0 2.1 2 1 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) PDZ PF00595.22 001246446.1_39725001_3 - 6.2e-20 71.2 2.9 1.7e-12 47.4 0.1 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.4 001246446.1_39725001_3 - 5.9e-11 42.4 0.2 1.9e-06 27.9 0.0 2.4 1 1 1 2 2 2 2 PDZ domain Synaptobrevin PF00957.19 001246583.1_39725001_2 - 1.3e-33 114.5 3.8 2.7e-33 113.5 3.8 1.5 1 0 0 1 1 1 1 Synaptobrevin zf-H2C2_2 PF13465.4 001246407.1_39724001_1 - 1.6e-88 287.3 82.6 5.9e-09 35.9 0.4 14.1 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.24 001246407.1_39724001_1 - 3.2e-73 238.2 85.6 5.9e-07 29.5 0.6 12.8 13 0 0 13 13 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001246407.1_39724001_1 - 1.9e-32 108.9 77.4 0.01 16.4 0.5 13.0 12 0 0 12 12 12 12 C2H2-type zinc finger KRAB PF01352.25 001246407.1_39724001_1 - 7.4e-23 79.8 0.0 1.6e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.6 001246407.1_39724001_1 - 3.2e-21 75.0 38.7 0.077 13.2 0.6 11.5 11 0 0 11 11 11 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.4 001246407.1_39724001_1 - 5.7e-18 64.3 63.3 0.04 13.8 1.0 12.6 12 0 0 12 12 12 10 C2H2-type zinc finger XPA_N PF01286.16 001246407.1_39724001_1 - 4.1e-14 52.2 42.6 1.2 9.1 0.2 12.4 12 0 0 12 12 12 7 XPA protein N-terminal Zn-ribbon_8 PF09723.8 001246407.1_39724001_1 - 1.2e-11 44.4 70.3 0.0011 18.9 2.2 8.9 3 2 7 11 11 10 8 Zinc ribbon domain zf-trcl PF13451.4 001246407.1_39724001_1 - 2.3e-07 30.5 52.3 1.6 8.5 0.1 11.9 10 2 0 10 10 10 4 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.3 001246407.1_39724001_1 - 1e-06 29.3 39.8 0.67 10.6 0.5 6.7 1 1 4 6 6 6 6 zinc-ribbon family DUF3268 PF11672.6 001246407.1_39724001_1 - 0.00099 19.3 35.8 0.22 11.8 0.8 6.5 2 2 4 8 8 8 5 zinc-finger-containing domain C1_4 PF07975.10 001246407.1_39724001_1 - 0.0069 16.5 50.4 0.78 9.9 0.8 8.3 1 1 9 11 11 11 4 TFIIH C1-like domain TFIIS_C PF01096.16 001246407.1_39724001_1 - 0.13 12.0 49.9 6.2 6.6 0.4 12.1 12 0 0 12 12 12 0 Transcription factor S-II (TFIIS) Raffinose_syn PF05691.10 001246407.1_39724001_1 - 0.21 9.2 8.4 4.6 4.8 0.1 3.7 3 1 1 4 4 4 0 Raffinose synthase or seed imbibition protein Sip1 GATA PF00320.25 001246407.1_39724001_1 - 1.7 8.2 31.6 4.5 6.8 0.1 9.7 12 0 0 12 12 12 0 GATA zinc finger YhfH PF14149.4 001246407.1_39724001_1 - 5.6 6.9 55.4 18 5.3 0.3 12.4 13 0 0 13 13 13 0 YhfH-like protein Mdv1 PF11542.6 001246407.1_39724001_3 - 0.18 11.7 0.1 0.47 10.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial division protein 1 Pkinase PF00069.23 001246616.1_39724001_1 - 8.8e-70 234.9 0.0 1.2e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001246616.1_39724001_1 - 1.1e-42 146.0 0.0 1.5e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.4 001246616.1_39724001_1 - 6.8e-06 25.5 0.4 3e-05 23.3 0.0 2.1 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.4 001246616.1_39724001_1 - 0.068 12.7 0.1 1 8.8 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 UPRTase PF14681.4 001280371.1_39724001_1 - 1.4e-72 243.4 0.0 2e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.16 001280371.1_39724001_1 - 1.4e-59 201.0 0.1 2e-59 200.5 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.10 001280371.1_39724001_1 - 4.2e-07 29.8 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.4 001280371.1_39724001_1 - 2.1e-05 24.9 0.0 4.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.4 001280371.1_39724001_1 - 0.0028 17.7 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.10 001280371.1_39724001_1 - 0.0033 16.6 0.0 0.0089 15.2 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin PF02224.16 001280371.1_39724001_1 - 0.0038 16.9 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase CoaE PF01121.18 001280371.1_39724001_1 - 0.025 14.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_17 PF13207.4 001280371.1_39724001_1 - 0.042 14.1 1.5 0.66 10.3 0.6 2.6 2 1 0 2 2 2 0 AAA domain Cyt-b5 PF00173.26 001279835.1_39725001_1 - 1.6e-24 85.7 0.0 3.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.22 001279835.1_39725001_1 - 2.7e-20 72.4 0.0 8e-20 70.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.19 001279835.1_39725001_1 - 8.1e-17 61.7 0.0 2.7e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CS PF04969.14 001279835.1_39725001_1 - 1.6e-11 44.9 1.2 3.9e-11 43.7 1.2 1.7 1 0 0 1 1 1 1 CS domain NAD_binding_6 PF08030.10 001279835.1_39725001_1 - 0.0011 19.0 0.0 0.0083 16.1 0.0 2.1 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Ada3 PF10198.7 001280239.1_39725001_3 - 6.8e-27 94.1 10.6 1.5e-25 89.7 10.9 2.4 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 YkyA PF10368.7 001280239.1_39725001_3 - 2 8.0 7.6 7.1 6.2 5.7 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein BST2 PF16716.3 001190480.1_39722001_1 - 4.3e-36 123.2 9.9 5.8e-36 122.8 9.9 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 MAD PF05557.11 001190480.1_39722001_1 - 2.2e-05 22.9 6.9 2.6e-05 22.7 6.9 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein CALCOCO1 PF07888.9 001190480.1_39722001_1 - 0.00037 19.1 4.7 0.00044 18.8 4.7 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.12 001190480.1_39722001_1 - 0.0025 17.5 11.8 0.0025 17.5 11.8 1.6 1 1 1 2 2 1 1 IncA protein DUF3450 PF11932.6 001190480.1_39722001_1 - 0.0027 16.9 5.1 0.0028 16.8 4.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) PRKG1_interact PF15898.3 001190480.1_39722001_1 - 0.004 17.9 5.9 0.0058 17.4 5.9 1.2 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain ATG16 PF08614.9 001190480.1_39722001_1 - 0.0045 17.1 10.6 0.0088 16.1 10.4 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.6 001190480.1_39722001_1 - 0.0046 17.0 6.0 0.0074 16.4 6.0 1.4 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4618 PF15397.4 001190480.1_39722001_1 - 0.0048 16.2 3.7 0.006 15.9 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) CCDC-167 PF15188.4 001190480.1_39722001_1 - 0.0052 17.0 4.7 0.011 15.9 4.7 1.7 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 Bap31 PF05529.10 001190480.1_39722001_1 - 0.0071 15.8 4.9 0.0071 15.8 4.9 1.4 2 0 0 2 2 1 1 B-cell receptor-associated protein 31-like TPR_MLP1_2 PF07926.10 001190480.1_39722001_1 - 0.0079 16.1 7.0 0.013 15.4 6.6 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.9 001190480.1_39722001_1 - 0.009 14.8 6.3 0.012 14.4 6.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.7 001190480.1_39722001_1 - 0.0096 15.8 4.8 0.0096 15.8 4.8 1.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.7 001190480.1_39722001_1 - 0.017 14.5 5.7 0.021 14.2 5.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 CASP_C PF08172.10 001190480.1_39722001_1 - 0.017 14.3 2.4 0.017 14.3 2.4 1.5 1 1 0 1 1 1 0 CASP C terminal Jnk-SapK_ap_N PF09744.7 001190480.1_39722001_1 - 0.019 15.1 5.5 0.026 14.6 5.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FliJ PF02050.14 001190480.1_39722001_1 - 0.02 15.0 5.5 0.033 14.3 5.5 1.4 1 1 0 1 1 1 0 Flagellar FliJ protein FlaC_arch PF05377.9 001190480.1_39722001_1 - 0.023 14.9 3.1 0.6 10.4 2.1 2.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.5 001190480.1_39722001_1 - 0.027 14.4 4.9 0.027 14.4 4.9 1.8 1 1 1 2 2 2 0 Tropomyosin like Filament PF00038.19 001190480.1_39722001_1 - 0.027 13.9 8.1 0.073 12.5 7.7 1.6 1 1 0 1 1 1 0 Intermediate filament protein THOC7 PF05615.11 001190480.1_39722001_1 - 0.028 14.6 5.6 0.039 14.1 5.6 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 EMP24_GP25L PF01105.22 001190480.1_39722001_1 - 0.03 14.1 1.1 0.049 13.4 1.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Seryl_tRNA_N PF02403.20 001190480.1_39722001_1 - 0.03 14.4 3.3 0.044 13.9 3.3 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cob_adeno_trans PF01923.16 001190480.1_39722001_1 - 0.032 14.2 1.1 0.042 13.8 1.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase HAUS-augmin3 PF14932.4 001190480.1_39722001_1 - 0.036 13.5 5.8 0.042 13.2 5.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Reo_sigmaC PF04582.10 001190480.1_39722001_1 - 0.038 13.3 1.3 0.047 13.0 1.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tektin PF03148.12 001190480.1_39722001_1 - 0.046 12.3 9.1 0.076 11.6 2.6 2.0 1 1 1 2 2 2 0 Tektin family APG6 PF04111.10 001190480.1_39722001_1 - 0.054 12.7 6.2 0.067 12.4 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.11 001190480.1_39722001_1 - 0.056 11.9 1.0 0.065 11.7 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CENP-Q PF13094.4 001190480.1_39722001_1 - 0.071 13.2 3.9 0.1 12.7 3.9 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Lebercilin PF15619.4 001190480.1_39722001_1 - 0.077 12.5 8.6 0.37 10.3 8.5 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GrpE PF01025.17 001190480.1_39722001_1 - 0.081 12.4 6.6 0.21 11.1 6.6 1.7 1 1 1 2 2 2 0 GrpE V_ATPase_I PF01496.17 001190480.1_39722001_1 - 0.084 10.6 2.5 0.1 10.4 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.9 001190480.1_39722001_1 - 0.086 13.0 8.6 0.064 13.4 4.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-H PF05837.10 001190480.1_39722001_1 - 0.094 13.0 9.1 0.2 12.0 7.9 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Mnd1 PF03962.13 001190480.1_39722001_1 - 0.11 12.2 4.8 0.15 11.8 4.8 1.1 1 0 0 1 1 1 0 Mnd1 family DUF1664 PF07889.10 001190480.1_39722001_1 - 0.12 12.3 3.8 3.4 7.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.11 001190480.1_39722001_1 - 0.13 12.8 4.4 0.092 13.2 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.4 001190480.1_39722001_1 - 0.15 12.3 7.2 0.25 11.6 7.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4472 PF14739.4 001190480.1_39722001_1 - 0.18 12.4 6.3 1.2 9.8 1.9 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Cluap1 PF10234.7 001190480.1_39722001_1 - 0.18 11.0 6.9 0.87 8.8 6.9 1.8 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF2205 PF10224.7 001190480.1_39722001_1 - 0.21 11.5 6.9 0.36 10.7 3.8 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) ZapB PF06005.10 001190480.1_39722001_1 - 0.23 11.8 9.1 0.13 12.5 4.0 2.2 1 1 1 2 2 2 0 Cell division protein ZapB GAS PF13851.4 001190480.1_39722001_1 - 0.23 10.7 9.0 0.13 11.5 5.1 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding KLRAQ PF10205.7 001190480.1_39722001_1 - 0.24 11.5 6.3 0.31 11.2 2.6 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein KELK PF15796.3 001190480.1_39722001_1 - 0.26 11.7 8.5 0.21 12.0 4.4 2.0 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SlyX PF04102.10 001190480.1_39722001_1 - 0.26 11.8 7.5 0.22 12.0 1.4 2.4 1 1 2 3 3 3 0 SlyX ERM PF00769.17 001190480.1_39722001_1 - 0.28 10.8 8.8 0.34 10.6 8.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Nup54 PF13874.4 001190480.1_39722001_1 - 0.3 11.0 7.3 0.25 11.3 2.5 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TMF_DNA_bd PF12329.6 001190480.1_39722001_1 - 0.33 10.9 6.5 0.091 12.6 3.4 1.7 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.3 001190480.1_39722001_1 - 0.44 10.7 7.9 1.3 9.2 3.1 2.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain Prefoldin_2 PF01920.18 001190480.1_39722001_1 - 0.45 10.4 7.6 1.5 8.7 7.6 1.7 1 1 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.10 001190480.1_39722001_1 - 0.53 10.7 3.1 2.5 8.5 0.6 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.11 001190480.1_39722001_1 - 0.6 9.2 3.2 0.78 8.8 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.15 001190480.1_39722001_1 - 0.63 9.8 6.6 0.76 9.6 2.5 2.1 1 1 1 2 2 2 0 Prefoldin subunit Fmp27_WPPW PF10359.7 001190480.1_39722001_1 - 0.66 8.6 4.4 0.83 8.3 4.4 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain APC_N_CC PF16689.3 001190480.1_39722001_1 - 0.73 9.8 4.6 0.69 9.9 3.0 1.7 2 0 0 2 2 1 0 Coiled-coil N-terminus of APC, dimerisation domain DUF4407 PF14362.4 001190480.1_39722001_1 - 1.2 8.3 9.0 0.13 11.4 4.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.12 001190480.1_39722001_1 - 1.6 8.6 10.1 7.7 6.4 10.1 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.13 001190480.1_39722001_1 - 2.6 7.7 10.2 2.1 8.0 3.8 2.9 1 1 2 3 3 3 0 Septum formation initiator DUF4140 PF13600.4 001190480.1_39722001_1 - 2.9 8.3 7.8 18 5.7 7.8 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF948 PF06103.9 001190480.1_39722001_1 - 4.1 7.6 6.3 1.1e+02 3.0 6.3 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DMAP1 PF05499.10 001246459.1_39724001_2 - 2.4e-74 248.6 8.4 4.8e-74 247.6 8.4 1.5 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.3 001246459.1_39724001_2 - 6.1e-33 112.7 4.1 1.2e-32 111.8 4.1 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF342 PF03961.11 001246459.1_39724001_2 - 2.3 6.6 5.6 2.5 6.5 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) PRMT5 PF05185.14 001280364.1_39725001_1 - 5.9e-172 572.6 0.0 5.9e-172 572.6 0.0 1.5 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase SAMBD PF16950.3 001280364.1_39725001_1 - 5.1e-104 347.9 1.2 3.2e-78 263.2 0.2 2.1 1 1 1 2 2 2 2 SAM-binding_domain Met_10 PF02475.14 001280364.1_39725001_1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Connexin PF00029.17 001280364.1_39725001_3 - 0.86 9.2 4.6 1.1 8.9 4.6 1.1 1 0 0 1 1 1 0 Connexin Claudin_2 PF13903.4 001280537.1_39725001_2 - 3.4e-21 75.8 1.5 5.5e-21 75.1 1.5 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.18 001280537.1_39725001_2 - 3.3e-10 40.0 5.8 6.9e-08 32.4 5.8 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Ribosomal_S25 PF03297.13 001251993.1_39722001_1 - 1.5e-49 166.2 8.0 2.1e-49 165.8 8.0 1.2 1 0 0 1 1 1 1 S25 ribosomal protein Mt_ATP-synt_D PF05873.10 001251993.1_39722001_1 - 0.02 14.6 0.2 0.027 14.2 0.2 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Fe_dep_repress PF01325.17 001251993.1_39722001_1 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.17 001251993.1_39722001_1 - 0.12 12.1 0.2 0.25 11.1 0.1 1.6 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB AIPR PF10592.7 001251993.1_39722001_1 - 0.15 11.6 0.5 0.19 11.2 0.6 1.3 1 1 0 1 1 1 0 AIPR protein HTH_24 PF13412.4 001251993.1_39722001_1 - 0.15 11.5 0.2 0.31 10.5 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TMEM189_B_dmain PF10520.7 001205079.2_39725001_2 - 1.8e-76 256.1 1.8 2.5e-76 255.6 1.8 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain SPARC_Ca_bdg PF10591.7 001098566.1_39726001_3 - 4.8e-41 139.5 0.4 4.8e-41 139.5 0.4 3.4 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.19 001098566.1_39726001_3 - 2e-13 50.0 4.6 2e-13 50.0 4.6 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.13 001098566.1_39726001_3 - 6.9e-12 45.2 2.4 3.3e-11 43.1 2.4 2.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain FOLN PF09289.8 001098566.1_39726001_3 - 5.7e-11 42.3 6.4 1.4e-10 41.0 6.4 1.7 1 0 0 1 1 1 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.30 001098566.1_39726001_3 - 0.013 14.8 0.0 0.039 13.4 0.0 1.7 1 0 0 1 1 1 0 EF hand AdoHcyase PF05221.15 001280434.1_39725001_2 - 1.9e-129 430.9 0.0 3e-68 230.0 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.19 001280434.1_39725001_2 - 6.2e-86 286.3 3.3 9.3e-86 285.8 3.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.17 001280434.1_39725001_2 - 1.8e-08 33.8 0.1 3.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.10 001280434.1_39725001_2 - 4.5e-05 23.0 0.1 9.1e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.16 001280434.1_39725001_2 - 0.0036 17.4 0.1 0.0067 16.5 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.16 001280434.1_39725001_2 - 0.068 12.9 1.0 0.22 11.2 1.0 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IF4E PF01652.16 001246470.1_39724001_1 - 3.9e-56 189.1 0.3 5.2e-56 188.7 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Yae1_N PF09811.7 001243954.1_39722001_2 - 4.2e-13 48.6 2.3 6.2e-13 48.1 2.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal P16-Arc PF04699.12 001246501.1_39724001_3 - 1.9e-59 200.3 0.0 2.6e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UTP15_C PF09384.8 001246501.1_39724001_3 - 0.054 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal Utp12 PF04003.10 001246501.1_39724001_3 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family 14-3-3 PF00244.18 001246368.1_39724001_1 - 1e-106 355.3 2.5 1.3e-106 355.0 2.5 1.1 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.15 001246368.1_39724001_1 - 0.097 10.9 3.3 0.15 10.3 3.3 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Smg8_Smg9 PF10220.7 001246560.1_39725001_1 - 2.3e-05 22.9 0.0 3.2e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Smg8_Smg9 OATP PF03137.18 001280332.1_39725001_1 - 8.2e-177 588.6 15.4 1.1e-176 588.3 15.4 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.14 001280332.1_39725001_1 - 4.4e-21 75.1 38.4 7.3e-21 74.3 30.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.13 001280332.1_39725001_1 - 8.4e-08 32.2 3.7 1.8e-07 31.1 3.7 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.19 001280332.1_39725001_1 - 0.00051 19.9 2.5 0.0013 18.6 2.5 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Cylicin_N PF15241.4 001246586.1_39724001_3 - 1.3e-44 150.6 1.0 1.3e-44 150.6 1.0 3.5 3 1 0 3 3 3 1 Cylicin N-terminus Arm PF00514.21 001271673.1_39725001_2 - 2e-88 287.9 18.8 1e-13 50.7 0.0 8.9 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.18 001271673.1_39725001_2 - 4.3e-24 84.6 4.5 1.1e-23 83.2 4.5 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.3 001271673.1_39725001_2 - 1.4e-23 82.1 0.9 4.6e-23 80.4 0.9 1.9 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.4 001271673.1_39725001_2 - 6.5e-23 80.7 1.8 2e-07 31.2 0.0 5.8 5 1 0 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.4 001271673.1_39725001_2 - 7.7e-21 74.1 0.1 5e-06 26.7 0.0 4.8 3 1 1 4 4 4 4 HEAT repeats HEAT PF02985.20 001271673.1_39725001_2 - 6.9e-14 50.6 7.9 0.0029 17.6 0.0 7.5 8 0 0 8 8 8 2 HEAT repeat RICTOR_V PF14668.4 001271673.1_39725001_2 - 4e-06 26.8 0.9 0.15 12.2 0.0 4.6 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.6 001271673.1_39725001_2 - 7.9e-06 25.9 0.0 0.13 12.2 0.0 4.2 3 1 1 4 4 4 2 V-ATPase subunit H Arm_2 PF04826.11 001271673.1_39725001_2 - 5.7e-05 22.6 0.0 0.33 10.2 0.0 2.6 2 1 1 3 3 3 2 Armadillo-like HEAT_PBS PF03130.14 001271673.1_39725001_2 - 0.0055 17.1 1.6 13 6.7 0.0 4.7 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat SEN1_N PF12726.5 001271673.1_39725001_2 - 0.035 12.2 0.1 2.5 6.1 0.0 2.9 2 1 1 3 3 3 0 SEN1 N terminal CTNNBL PF08216.9 001271673.1_39725001_2 - 0.052 13.6 0.0 4.7 7.3 0.0 3.6 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear NUSAP PF16006.3 001271673.1_39725001_2 - 0.56 9.8 4.4 0.82 9.2 4.4 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein Guanylate_kin PF00625.19 001246656.2_39724001_1 - 9.7e-51 171.9 0.1 1.9e-50 171.0 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.14 001246656.2_39724001_1 - 1.2e-28 98.5 2.0 5.8e-17 61.1 0.1 3.1 3 0 0 3 3 3 2 L27 domain SH3_2 PF07653.15 001246656.2_39724001_1 - 1.1e-11 44.0 0.2 3.5e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PDZ PF00595.22 001246656.2_39724001_1 - 1.1e-10 41.6 0.9 2.2e-10 40.6 0.9 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_1 PF00018.26 001246656.2_39724001_1 - 5.6e-06 25.7 0.1 1.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.4 001246656.2_39724001_1 - 4.9e-05 23.0 0.0 9.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.4 001246656.2_39724001_1 - 0.00017 21.7 0.1 0.0004 20.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.4 001246656.2_39724001_1 - 0.00087 19.1 0.1 0.013 15.3 0.2 2.6 2 1 0 2 2 2 1 Tricorn protease PDZ domain cNMP_binding PF00027.27 001279948.1_39724001_2 - 7.5e-42 141.1 0.1 2.3e-21 75.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.15 001279948.1_39724001_2 - 1e-16 60.2 0.1 2e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit LSM PF01423.20 001247981.1_39722001_1 - 1.2e-12 47.2 0.0 1.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain bZIP_1 PF00170.19 001098421.1_39723001_1 - 6.7e-09 35.6 14.0 1e-08 35.0 14.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001098421.1_39723001_1 - 3.6e-06 26.8 14.1 5.7e-06 26.2 14.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001098421.1_39723001_1 - 3.6e-05 24.1 8.9 5.6e-05 23.5 8.9 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.7 001098421.1_39723001_1 - 0.022 13.2 8.5 0.032 12.7 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3450 PF11932.6 001098421.1_39723001_1 - 0.11 11.7 1.8 0.15 11.2 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HALZ PF02183.16 001098421.1_39723001_1 - 0.23 11.6 4.4 0.62 10.2 4.2 1.8 1 1 0 1 1 1 0 Homeobox associated leucine zipper EF-1_beta_acid PF10587.7 001098421.1_39723001_1 - 0.53 10.6 4.9 1.2 9.6 4.9 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Mnd1 PF03962.13 001098421.1_39723001_1 - 0.81 9.4 5.5 1.2 8.8 5.5 1.2 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.10 001098421.1_39723001_1 - 1.1 8.5 5.7 1.6 8.0 5.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc97_Spc98 PF04130.11 001279794.1_39725001_1 - 1.4e-94 317.7 12.4 1.4e-92 311.1 12.4 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family MHC_I PF00129.16 001130467.1_39723001_1 - 1.7e-92 307.8 0.8 2.5e-92 307.2 0.8 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 001130467.1_39723001_1 - 3.9e-16 59.2 0.0 8.5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 001130467.1_39723001_1 - 4.2e-15 55.2 3.4 7.7e-15 54.4 3.4 1.5 1 0 0 1 1 1 1 MHC_I C-terminus C2-set_2 PF08205.10 001130467.1_39723001_1 - 0.00049 20.0 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 001130467.1_39723001_1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain DUF202 PF02656.13 001130467.1_39723001_1 - 0.052 13.9 0.2 5.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Podoplanin PF05808.9 001130467.1_39723001_1 - 0.17 11.9 0.2 0.38 10.7 0.2 1.5 1 0 0 1 1 1 0 Podoplanin Pkinase PF00069.23 001280387.1_39724001_3 - 7.4e-66 222.1 0.0 9e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280387.1_39724001_3 - 1.4e-26 93.3 0.0 1.9e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.21 001280387.1_39724001_3 - 0.013 15.3 0.1 0.065 13.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.4 001280387.1_39724001_3 - 0.14 11.4 0.0 2 7.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.12 001280387.1_39724001_3 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ThiF PF00899.19 001246388.2_39724001_3 - 4.4e-22 78.5 0.0 9.8e-22 77.4 0.0 1.6 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.3 001246388.2_39724001_3 - 4.6e-05 23.4 0.0 0.038 14.0 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle Maelstrom PF13017.4 001279868.1_39724001_2 - 6.8e-58 195.7 0.5 1.1e-57 195.1 0.5 1.2 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.8 001279868.1_39724001_2 - 4.4e-25 87.9 0.5 7.6e-25 87.2 0.5 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.17 001279868.1_39724001_2 - 9.4e-06 25.8 0.5 2.1e-05 24.7 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box CD225 PF04505.10 001198767.1_39722001_1 - 3.8e-32 110.1 0.8 5.6e-32 109.6 0.8 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein bZIP_1 PF00170.19 001252517.1_39723001_1 - 2.5e-17 62.6 15.5 3.7e-17 62.0 15.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001252517.1_39723001_1 - 6.1e-07 29.3 13.4 6.1e-07 29.3 13.4 1.6 1 1 0 1 1 1 1 Basic region leucine zipper DUF3450 PF11932.6 001252517.1_39723001_1 - 0.00062 19.0 1.9 0.00088 18.5 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) IncA PF04156.12 001252517.1_39723001_1 - 0.0088 15.7 2.3 0.013 15.2 2.3 1.1 1 0 0 1 1 1 1 IncA protein Taxilin PF09728.7 001252517.1_39723001_1 - 0.041 13.0 11.6 0.058 12.5 11.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Fez1 PF06818.13 001252517.1_39723001_1 - 0.043 14.1 7.9 0.065 13.5 7.9 1.1 1 0 0 1 1 1 0 Fez1 DUF4407 PF14362.4 001252517.1_39723001_1 - 0.075 12.2 4.5 0.11 11.8 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.10 001252517.1_39723001_1 - 0.54 10.1 6.0 0.8 9.6 6.0 1.2 1 0 0 1 1 1 0 Laminin Domain II bZIP_Maf PF03131.15 001252517.1_39723001_1 - 0.68 10.4 8.6 1.1 9.7 8.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Nop53 PF07767.9 001252517.1_39723001_1 - 0.8 8.9 14.1 1.1 8.4 14.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) AAA_13 PF13166.4 001252517.1_39723001_1 - 0.84 8.1 9.8 1.1 7.8 9.8 1.0 1 0 0 1 1 1 0 AAA domain DUF4795 PF16043.3 001252517.1_39723001_1 - 0.86 9.0 8.3 2 7.8 8.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Baculo_F PF12259.6 001252517.1_39723001_1 - 0.95 7.8 2.8 1.3 7.3 2.8 1.1 1 0 0 1 1 1 0 Baculovirus F protein APG6 PF04111.10 001252517.1_39723001_1 - 1.4 8.1 9.2 2 7.6 9.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.13 001252517.1_39723001_1 - 3.6 7.3 11.0 1.7 8.3 7.3 1.9 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.10 001252517.1_39723001_1 - 6.7 7.1 11.5 0.28 11.5 4.3 2.0 1 1 1 2 2 2 0 Cell division protein ZapB Mnd1 PF03962.13 001252517.1_39723001_1 - 7.5 6.2 13.2 5 6.8 11.6 1.4 2 0 0 2 2 1 0 Mnd1 family Peptidase_S28 PF05577.10 001279874.1_39725001_2 - 9.5e-81 271.7 0.0 1.1e-57 195.7 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.18 001279874.1_39725001_2 - 2.6e-06 27.1 0.1 5.4e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.6 001279874.1_39725001_2 - 6.5e-05 22.2 0.2 0.0001 21.5 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.9 001279874.1_39725001_2 - 0.0037 15.9 0.0 0.008 14.8 0.0 1.5 2 0 0 2 2 2 1 PS-10 peptidase S37 Peptidase_S9 PF00326.19 001279874.1_39725001_2 - 0.0064 15.9 0.1 0.0099 15.2 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.6 001279874.1_39725001_2 - 0.12 11.4 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_2 PF02230.14 001279874.1_39725001_2 - 0.19 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase zf-4CXXC_R1 PF10497.7 001280512.1_39726001_3 - 5.3e-37 125.9 11.0 1e-36 125.0 11.0 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Endonuclease_7 PF02945.13 001280512.1_39726001_3 - 7.6 6.4 14.5 9.8 6.1 8.2 2.4 1 1 1 2 2 2 0 Recombination endonuclease VII adh_short PF00106.23 001280319.1_39725001_3 - 3.1e-58 196.3 0.1 4.1e-58 195.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.4 001280319.1_39725001_3 - 3.6e-29 101.9 0.0 5.3e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.8 001280319.1_39725001_3 - 2.6e-13 50.2 0.2 4e-13 49.5 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.4 001280319.1_39725001_3 - 0.005 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.13 001280319.1_39725001_3 - 0.009 15.1 0.2 0.013 14.5 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Fic PF02661.16 001280284.1_39724001_2 - 1.9e-27 95.9 0.0 4.3e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family TPR_2 PF07719.15 001280284.1_39724001_2 - 0.0015 18.4 0.6 0.028 14.4 0.3 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.4 001280284.1_39724001_2 - 0.0042 17.0 0.8 0.076 13.1 0.3 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.4 001280284.1_39724001_2 - 0.054 13.7 0.2 0.36 11.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.26 001280284.1_39724001_2 - 0.092 12.5 0.8 1.4 8.7 0.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Serpin PF00079.18 001280360.1_39725001_2 - 4.6e-115 384.7 2.3 5.5e-115 384.5 2.3 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Glyco_transf_7N PF13733.4 001246636.1_39724001_3 - 1.1e-56 190.0 0.0 1.5e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.12 001246636.1_39724001_3 - 3.9e-30 103.2 0.1 1.1e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase CREPT PF16566.3 001242592.1_39728001_3 - 9.6e-62 207.4 5.9 1.9e-61 206.4 5.9 1.5 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.11 001242592.1_39728001_3 - 2e-21 76.4 0.5 5.5e-21 75.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.6 001242592.1_39728001_3 - 0.031 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 ATP-synt_ab PF00006.23 001280322.1_39726001_1 - 1.2e-67 227.5 0.0 1.6e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.21 001280322.1_39726001_1 - 1.1e-12 48.1 0.1 2.6e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain GLTP PF08718.9 001199079.2_39729001_1 - 4.9e-42 143.6 0.0 8.1e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH PF00169.27 001199079.2_39729001_1 - 4.5e-11 43.0 0.1 1.5e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.4 001199079.2_39729001_1 - 0.0007 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.4 001199079.2_39729001_1 - 0.0018 18.5 0.1 0.0058 16.9 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain TLV_coat PF00429.17 001135588.1_39724001_1 - 2.1e-09 36.5 0.2 0.00072 18.2 0.0 2.3 2 0 0 2 2 2 2 ENV polyprotein (coat polyprotein) GN3L_Grn1 PF08701.9 001280285.1_39724001_2 - 2.9e-21 75.2 22.5 2.9e-21 75.2 22.5 3.7 4 0 0 4 4 4 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.21 001280285.1_39724001_2 - 7.7e-12 45.2 0.1 7.5e-10 38.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.16 001280285.1_39724001_2 - 1.2e-06 28.0 0.4 0.0021 17.5 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.14 001280285.1_39724001_2 - 1.8e-05 24.6 2.2 0.066 13.0 2.2 2.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001280285.1_39724001_2 - 0.00024 20.6 0.0 0.0039 16.6 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.14 001280285.1_39724001_2 - 0.0036 16.2 0.1 0.011 14.6 0.1 1.8 1 0 0 1 1 1 1 ArgK protein SRPRB PF09439.8 001280285.1_39724001_2 - 0.06 12.7 1.1 0.49 9.7 0.0 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF3699 PF12480.6 001246563.1_39724001_1 - 2.7e-28 97.8 0.1 4.4e-28 97.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3699) AIB PF15334.4 001243839.1_39723001_1 - 2.4e-182 605.4 10.0 2.7e-182 605.2 10.0 1.0 1 0 0 1 1 1 1 Aurora kinase A and ninein interacting protein GSHPx PF00255.17 001145825.2_39724001_3 - 5.3e-35 119.1 0.7 8.6e-35 118.5 0.7 1.3 1 0 0 1 1 1 1 Glutathione peroxidase SNAP PF14938.4 001246629.1_39724001_2 - 3.8e-109 364.4 20.6 4.6e-109 364.1 20.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.4 001246629.1_39724001_2 - 4.3e-06 26.8 12.9 0.0046 17.1 1.0 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.4 001246629.1_39724001_2 - 0.006 16.4 5.2 1.3 9.1 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.26 001246629.1_39724001_2 - 0.024 14.3 7.6 2.4 8.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Spatacsin_C PF14649.4 001246629.1_39724001_2 - 0.046 12.7 7.0 1.1 8.2 1.8 2.3 1 1 1 2 2 2 0 Spatacsin C-terminus NSF PF02071.18 001246629.1_39724001_2 - 0.064 13.9 34.6 11 7.2 1.3 7.9 7 0 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat TPR_6 PF13174.4 001246629.1_39724001_2 - 1.1 10.0 10.3 13 6.5 0.2 5.1 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.4 001246629.1_39724001_2 - 1.8 8.9 17.2 3.4 8.0 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.15 001246629.1_39724001_2 - 2.6 8.2 16.0 7.4 6.8 0.0 5.4 4 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.4 001246629.1_39724001_2 - 4.1 7.3 7.4 17 5.3 0.0 4.5 4 1 2 6 6 6 0 Tetratricopeptide repeat Ran_BP1 PF00638.16 001246415.1_39727001_1 - 1.3e-13 51.1 0.0 2.1e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain SPRY PF00622.26 001280515.1_39726001_2 - 6.9e-13 48.7 0.2 1.3e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 SPRY domain PHD20L1_u1 PF16660.3 001280515.1_39726001_2 - 0.4 11.3 2.2 0.92 10.2 2.2 1.5 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 SSXT PF05030.10 001246581.1_39724001_3 - 3.9e-29 99.9 4.3 6.4e-29 99.3 4.3 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) B56 PF01603.18 001328314.1_39724001_2 - 2.7e-192 639.2 12.1 3.6e-192 638.7 12.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.5 001328314.1_39724001_2 - 0.073 12.9 4.5 1.8 8.4 0.6 2.8 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal OAS1_C PF10421.7 001280469.1_39725001_2 - 4e-78 261.0 0.2 7e-78 260.3 0.2 1.4 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus ubiquitin PF00240.21 001280469.1_39725001_2 - 1.1e-19 69.8 0.0 1.1e-16 60.1 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.6 001280469.1_39725001_2 - 5.6e-08 32.4 0.0 1.4e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like SCAN PF02023.15 001280469.1_39725001_2 - 0.0098 15.6 1.1 0.056 13.1 0.4 2.5 3 0 0 3 3 3 1 SCAN domain V-set PF07686.15 001194945.1_39722001_2 - 1.1e-09 38.2 0.1 1.9e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.4 001194945.1_39722001_2 - 0.0028 17.8 0.2 0.014 15.6 0.2 2.1 1 1 0 1 1 1 1 Immunoglobulin domain SAM_1 PF00536.28 001279830.1_39725001_1 - 5.4e-11 42.6 0.0 2e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.15 001279830.1_39725001_1 - 6.2e-11 42.1 0.0 1.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CPSF73-100_C PF11718.6 001246367.1_39725001_2 - 7.5e-54 182.4 0.3 1.2e-53 181.7 0.3 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.6 001246367.1_39725001_2 - 3.3e-34 117.4 0.0 6.7e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.10 001246367.1_39725001_2 - 8.7e-22 76.7 0.2 2.1e-21 75.5 0.2 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.25 001246367.1_39725001_2 - 7.2e-19 68.4 0.1 1.2e-18 67.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.3 001246367.1_39725001_2 - 7.9e-19 67.7 0.0 2.7e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.5 001246367.1_39725001_2 - 7.2e-08 32.1 0.3 5.1e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.4 001246367.1_39725001_2 - 4.1e-06 26.7 0.2 8.4e-05 22.4 0.0 3.0 2 1 1 3 3 3 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.3 001246367.1_39725001_2 - 0.00093 18.4 0.1 0.0019 17.3 0.1 1.5 1 0 0 1 1 1 1 Putative beta-lactamase-like family CIAPIN1 PF05093.11 001246624.1_39724001_1 - 9.4e-23 80.5 18.2 3.7e-17 62.5 3.6 2.8 2 1 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_11 PF08241.10 001246624.1_39724001_1 - 5.6e-05 23.6 0.3 0.00015 22.2 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.4 001246624.1_39724001_1 - 0.00013 21.7 0.0 0.00085 19.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.4 001246624.1_39724001_1 - 0.018 15.6 0.0 0.043 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Tat PF00539.16 001246624.1_39724001_1 - 0.099 12.7 0.4 0.099 12.7 0.4 2.8 3 0 0 3 3 3 0 Transactivating regulatory protein (Tat) Methyltransf_23 PF13489.4 001243095.1_39725001_3 - 0.0019 18.0 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.4 001243095.1_39725001_3 - 0.024 15.2 0.0 0.048 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain B3_4 PF03483.15 001246538.1_39724001_3 - 1.6e-26 92.9 0.1 3.4e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.13 001246538.1_39724001_3 - 1.7e-15 56.9 1.0 4.5e-13 49.2 0.1 3.4 4 0 0 4 4 4 2 tRNA synthetase B5 domain CAP PF00188.24 001280374.1_39724001_3 - 4.5e-20 72.6 0.4 7.7e-20 71.9 0.4 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PTH2 PF01981.14 001242625.1_39722001_3 - 4.9e-24 84.7 0.0 6.1e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RPAP1_C PF08620.8 001242625.1_39722001_3 - 0.067 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 RPAP1-like, C-terminal Oxysterol_BP PF01237.16 001280144.1_39726001_2 - 2.7e-81 273.1 8.2 3.3e-79 266.2 8.2 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.27 001280144.1_39726001_2 - 7.4e-14 52.0 0.0 2.5e-13 50.3 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.4 001280144.1_39726001_2 - 1.4e-08 34.8 0.3 2.7e-08 33.9 0.3 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.4 001280144.1_39726001_2 - 9.9e-06 25.8 6.2 4.1e-05 23.8 3.0 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.4 001280144.1_39726001_2 - 0.00045 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Snapin_Pallidin PF14712.4 001280144.1_39726001_2 - 0.25 11.7 4.9 0.061 13.6 1.4 1.7 2 0 0 2 2 2 0 Snapin/Pallidin Snurportin1 PF11538.6 001328317.1_39724001_1 - 1e-17 63.9 9.0 2.1e-17 62.9 9.0 1.5 1 0 0 1 1 1 1 Snurportin1 IBB PF01749.18 001328317.1_39724001_1 - 0.075 13.3 3.0 0.17 12.1 3.0 1.6 1 0 0 1 1 1 0 Importin beta binding domain Clathrin_H_link PF13838.4 001243909.1_39724001_1 - 1.2e-12 47.4 0.0 3.2e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Clathrin-H-link Nucleopor_Nup85 PF07575.11 001243909.1_39724001_1 - 0.014 13.9 7.3 0.035 12.6 3.2 2.2 2 0 0 2 2 2 0 Nup85 Nucleoporin Retrotrans_gag PF03732.15 001243909.1_39724001_1 - 0.058 13.5 0.2 18 5.5 0.0 3.1 2 1 1 3 3 3 0 Retrotransposon gag protein Clathrin PF00637.18 001243909.1_39724001_1 - 1.3 8.7 6.6 0.38 10.5 0.1 3.0 3 1 0 3 3 3 0 Region in Clathrin and VPS Metallothio PF00131.18 125723.1_39721120_2 - 7.5e-13 48.3 33.3 1.1e-12 47.8 33.3 1.1 1 0 0 1 1 1 1 Metallothionein LINES_C PF14695.4 125723.1_39721120_2 - 0.067 12.5 0.1 0.067 12.5 0.1 2.2 2 1 1 3 3 3 0 Lines C-terminus VESA1_N PF12785.5 125723.1_39721120_2 - 9.6 4.9 22.4 11 4.7 22.4 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 ARA70 PF12489.6 073402.2_39726120_1 - 6.5e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear coactivator ARA70 PF12489.6 073402.2_39726120_2 - 0.078 13.0 3.5 3.4 7.7 0.2 3.3 2 1 1 3 3 3 0 Nuclear coactivator IncA PF04156.12 132631.1_39721120_1 - 0.031 14.0 6.4 0.033 13.8 6.4 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.10 132631.1_39721120_1 - 0.094 12.0 6.4 0.11 11.8 6.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.11 132631.1_39721120_1 - 0.53 10.8 4.8 0.74 10.3 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CENP-H PF05837.10 132631.1_39721120_1 - 0.8 10.0 9.6 1.1 9.6 9.6 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) NuA4 PF09340.8 132631.1_39721120_1 - 0.97 9.2 2.7 2.2 8.1 0.6 2.2 1 1 1 2 2 2 0 Histone acetyltransferase subunit NuA4 OmpH PF03938.12 132631.1_39721120_1 - 1.7 8.5 11.2 2.6 7.9 11.2 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MHC_I PF00129.16 024036.1_39723120_3 - 5e-93 309.5 1.5 7.2e-93 309.0 1.5 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 024036.1_39723120_3 - 1.5e-17 63.7 0.0 4.7e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I_C PF06623.9 024036.1_39723120_3 - 1.2e-13 50.6 7.7 2e-13 49.8 7.7 1.4 1 0 0 1 1 1 1 MHC_I C-terminus Ig_3 PF13927.4 024036.1_39723120_3 - 2.5e-06 27.9 0.9 0.042 14.3 0.0 3.2 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 024036.1_39723120_3 - 0.00052 19.9 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.23 024036.1_39723120_3 - 0.0041 17.1 0.1 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain EphA2_TM PF14575.4 024036.1_39723120_3 - 0.12 13.1 0.1 0.36 11.5 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Defensin_beta_2 PF13841.4 036558.1_39721120_1 - 0.00038 20.7 2.3 0.00038 20.7 2.3 1.5 2 0 0 2 2 2 1 Beta defensin PIP5K PF01504.16 024414.2_39728120_3 - 3.5e-89 298.6 0.0 6.7e-89 297.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase VWA_2 PF13519.4 024414.2_39728120_3 - 4.6e-20 72.2 0.0 1.2e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.12 024414.2_39728120_3 - 2.8e-05 23.9 0.1 4.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like Glyco_transf_6 PF03414.11 132137.2_39727120_2 - 1.5e-50 171.7 5.1 1.8e-50 171.4 2.0 1.9 1 1 1 2 2 2 2 Glycosyltransferase family 6 Glyco_transf_6 PF03414.11 132137.2_39727120_3 - 4.6e-40 137.2 0.2 6.5e-40 136.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 6 MHC_II_beta PF00969.17 036548.1_39722120_1 - 3e-25 88.0 0.2 5e-25 87.3 0.2 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.13 036548.1_39722120_2 - 6.3e-26 90.5 0.1 1.3e-25 89.5 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.23 036548.1_39722120_2 - 0.00021 21.3 0.1 0.00042 20.3 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain TSC22 PF01166.16 001279934.1_39724001_3 - 0.0036 17.4 6.6 0.18 12.0 0.5 3.3 2 0 0 2 2 2 2 TSC-22/dip/bun family Nod1 PF17114.3 001279934.1_39724001_3 - 0.011 15.7 2.3 1.7 8.7 0.1 2.5 2 1 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 DUF4618 PF15397.4 001279934.1_39724001_3 - 0.082 12.2 25.1 0.14 11.4 25.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.19 001279934.1_39724001_3 - 1.8 8.6 10.0 4.3 7.4 0.7 3.3 3 0 0 3 3 3 0 bZIP transcription factor DivIC PF04977.13 001279934.1_39724001_3 - 3.1 7.5 9.7 5.4 6.7 0.9 3.2 3 0 0 3 3 3 0 Septum formation initiator APOBEC_N PF08210.9 001161381.2_39522001_2 - 5.8e-40 137.0 0.5 6.9e-40 136.7 0.5 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001161381.2_39522001_2 - 2.7e-30 104.0 0.3 4.2e-30 103.4 0.3 1.3 1 0 0 1 1 1 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.21 001161381.2_39522001_2 - 0.0027 17.4 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF929 PF06053.9 001161381.2_39522001_2 - 0.017 14.3 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) MafB19-deam PF14437.4 001161381.2_39522001_2 - 0.086 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase Phosphodiest PF01663.20 144330.1_26228120_2 - 7.9e-11 42.0 0.1 7.9e-07 28.9 0.0 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.16 144330.1_26228120_2 - 0.0078 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily CDP-OH_P_transf PF01066.19 001199841.1_37927001_3 - 1.1e-16 61.2 0.1 1.1e-16 61.2 0.1 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Selenoprotein_S PF06936.9 001199926.1_08023001_1 - 5.8e-95 316.5 1.4 7.4e-95 316.1 1.4 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) Rdx PF10262.7 001146709.1_39724001_2 - 7.6e-08 32.3 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Rdx family DUF963 PF06131.9 001146709.1_39724001_2 - 8.5 5.8 32.7 0.2 11.0 15.5 3.8 2 1 1 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) SelP_N PF04592.12 001199846.1_37925001_3 - 1.5e-99 332.0 5.2 2.3e-99 331.4 5.2 1.2 1 0 0 1 1 1 1 Selenoprotein P, N terminal region SelP_C PF04593.12 001199846.1_37925001_3 - 6.6e-31 107.0 11.8 1.7e-30 105.6 11.8 1.7 1 0 0 1 1 1 1 Selenoprotein P, C terminal region SelP_N PF04592.12 001199928.1_08025001_3 - 6.4e-100 333.2 8.2 6.4e-100 333.2 8.2 1.4 1 1 1 2 2 2 1 Selenoprotein P, N terminal region SelP_C PF04593.12 001199928.1_08025001_3 - 2.3e-19 69.6 4.9 2.3e-19 69.6 4.9 1.9 2 0 0 2 2 2 1 Selenoprotein P, C terminal region Sep15_SelM PF08806.9 001199842.1_37922001_1 - 1.1e-22 79.8 0.0 1.6e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Sep15/SelM redox domain Rdx PF10262.7 001154577.3_39722001_2 - 2.3e-06 27.5 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Rdx family FixO PF02433.13 001154577.3_39722001_3 - 0.018 14.3 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Rdx PF10262.7 001199976.1_43524001_3 - 7.6e-08 32.3 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Rdx family Rdx PF10262.7 001199901.1_08023001_1 - 0.00025 21.1 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 Rdx family Sep15_SelM PF08806.9 001161648.1_49822001_1 - 1.8e-21 76.0 0.0 4.1e-21 74.8 0.0 1.5 2 0 0 2 2 2 1 Sep15/SelM redox domain SelP_N PF04592.12 001285582.1_09024001_2 - 8.5e-98 326.3 5.2 1.1e-97 326.0 5.2 1.1 1 0 0 1 1 1 1 Selenoprotein P, N terminal region SelP_C PF04593.12 001285582.1_09024001_2 - 2.9e-31 108.1 13.3 2.9e-31 108.1 13.3 2.2 2 1 0 2 2 2 1 Selenoprotein P, C terminal region SelK_SelG PF10961.6 001199833.1_37922001_1 - 2.3e-28 98.5 0.2 2.3e-28 98.5 0.2 1.7 2 0 0 2 2 2 1 Selenoprotein SelK_SelG SelK_SelG PF10961.6 001199915.1_08022001_2 - 9.9e-29 99.7 0.1 1.8e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Rdx PF10262.7 001258348.1_09922001_2 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Rdx family Rdx PF10262.7 001166045.1_49823001_2 - 1.7e-09 37.6 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Rdx family DUF963 PF06131.9 001166045.1_49823001_2 - 8.6e-05 21.7 41.4 0.00057 19.1 17.1 4.9 4 1 2 6 6 6 4 Schizosaccharomyces pombe repeat of unknown function (DUF963) SelP_N PF04592.12 001258007.1_09924001_1 - 6.2e-81 271.1 0.1 8.6e-81 270.6 0.1 1.1 1 0 0 1 1 1 1 Selenoprotein P, N terminal region SelP_C PF04593.12 001258007.1_09924001_1 - 9.3e-40 135.6 14.0 1.6e-39 134.9 14.0 1.3 1 0 0 1 1 1 1 Selenoprotein P, C terminal region Selenoprotein_S PF06936.9 001114756.1_39723001_2 - 9.5e-93 309.2 2.8 1.3e-92 308.8 2.8 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) LCD1 PF09798.7 001114756.1_39723001_2 - 1.5 7.1 5.9 2 6.7 5.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CDP-OH_P_transf PF01066.19 001146697.2_39729001_1 - 5.9e-16 58.9 0.1 5.9e-16 58.9 0.1 2.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Rdx PF10262.7 001146691.1_39723001_3 - 0.00021 21.3 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Rdx family P_proprotein PF01483.18 001146691.1_39723001_3 - 0.082 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain DEAD PF00270.27 001193491.1_29623001_2 - 3.5e-39 134.2 0.0 6e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001193491.1_29623001_2 - 1.2e-25 89.9 0.8 7.9e-24 84.0 0.2 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.4 001193491.1_29623001_2 - 1.1e-06 28.1 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.13 001193491.1_29623001_2 - 5.4e-06 26.4 0.0 9.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.27 001266562.1_29625001_2 - 2.5e-79 265.0 0.0 4e-79 264.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001266562.1_29625001_2 - 1.2e-27 96.4 0.0 3.5e-27 94.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.26 001266562.1_29625001_2 - 2.5e-24 85.6 0.1 5.3e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 SPRY domain CMS1 PF14617.4 001266562.1_29625001_2 - 0.0051 16.1 0.0 0.024 13.8 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.13 001266562.1_29625001_2 - 0.0093 15.8 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.27 001283962.1_29524001_1 - 4.6e-39 133.9 0.1 7.3e-39 133.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001283962.1_29524001_1 - 7.8e-25 87.3 0.5 1.5e-22 79.9 0.1 2.5 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.13 001283962.1_29524001_1 - 1.3e-07 31.6 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.4 001283962.1_29524001_1 - 2.1e-06 27.2 0.1 4.1e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit dsrm PF00035.24 001266188.1_29629001_2 - 1.8e-26 92.5 2.4 6.5e-12 45.8 0.1 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.14 001266188.1_29629001_2 - 3.8e-16 59.1 0.0 8.4e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.29 001266188.1_29629001_2 - 1.1e-15 57.8 0.0 2.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.21 001266188.1_29629001_2 - 4.2e-15 55.8 0.0 9.7e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.27 001266188.1_29629001_2 - 8.9e-07 28.7 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.18 001266188.1_29629001_2 - 0.015 14.2 0.0 0.049 12.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.4 001266188.1_29629001_2 - 0.02 14.8 0.0 0.07 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.13 001266188.1_29629001_2 - 0.029 14.2 0.0 0.21 11.5 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Dicer_dimer PF03368.12 001266188.1_29629001_2 - 0.036 14.1 0.1 0.78 9.8 0.0 2.6 2 0 0 2 2 2 0 Dicer dimerisation domain AAA_22 PF13401.4 001266188.1_29629001_2 - 0.038 14.1 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase PF06745.11 001266188.1_29629001_2 - 0.042 13.1 0.0 0.13 11.4 0.0 1.8 1 0 0 1 1 1 0 KaiC PhoH PF02562.14 001266188.1_29629001_2 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.4 001266188.1_29629001_2 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.27 001258182.1_29626001_2 - 3.1e-47 160.5 0.0 5e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001258182.1_29626001_2 - 3.3e-31 107.8 0.1 3.2e-28 98.2 0.0 3.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.10 001258182.1_29626001_2 - 1.5e-27 95.5 0.0 3.8e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.13 001258182.1_29626001_2 - 2.9e-10 40.3 0.0 7.8e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.4 001258182.1_29626001_2 - 1.8e-06 27.3 0.0 1.8e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.3 001258182.1_29626001_2 - 0.00053 19.1 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.4 001258182.1_29626001_2 - 0.015 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.4 001258182.1_29626001_2 - 0.32 10.6 0.0 0.32 10.6 0.0 2.5 1 1 1 2 2 2 0 AAA domain DUF846 PF05832.10 001281825.1_39524001_3 - 2.1e-55 186.4 8.6 2.1e-55 186.4 8.6 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF846) DUF846 PF05832.10 001281811.1_39724001_3 - 1.6e-54 183.5 10.0 3.1e-54 182.6 10.0 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF846 PF05832.10 001281984.1_09922001_1 - 3.4e-55 185.8 9.7 4.2e-55 185.5 9.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMC PF07810.11 001281984.1_09922001_1 - 0.064 13.7 0.1 0.064 13.7 0.1 1.6 2 0 0 2 2 2 0 TMC domain HXXEE PF13787.4 001281984.1_09922001_1 - 4.5 7.9 8.0 4.9e+02 1.4 8.0 2.1 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif DUF846 PF05832.10 001281813.1_39724001_3 - 1.7e-54 183.5 10.0 3.1e-54 182.7 10.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF846 PF05832.10 001281861.1_37624001_1 - 4.3e-54 182.2 9.7 6.4e-54 181.6 9.7 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF846 PF05832.10 001281863.1_37923001_1 - 4.1e-55 185.5 9.6 4.1e-55 185.5 9.6 1.6 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF846) zf-Tim10_DDP PF02953.13 001261523.1_29621001_1 - 4.5e-23 80.5 0.7 6.3e-23 80.1 0.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger APOBEC_N PF08210.9 001071809.3_39726001_2 - 1.3e-60 204.2 0.3 1.8e-60 203.8 0.3 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.12 001071809.3_39726001_2 - 4.7e-28 96.8 0.1 8.4e-28 96.0 0.1 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain RcbX PF02341.13 001071809.3_39726001_2 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 RbcX protein HEAT PF02985.20 144409.1_26229120_1 - 0.095 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat HEAT PF02985.20 144409.1_26229120_2 - 4e-06 26.5 0.2 0.076 13.2 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.4 144409.1_26229120_2 - 0.0014 18.8 0.0 0.0047 17.2 0.0 1.8 2 0 0 2 2 2 1 HEAT repeats TMF_TATA_bd PF12325.6 144409.1_26229120_3 - 0.049 13.7 1.8 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding STN1_2 PF09170.8 001266590.1_29625001_3 - 6.5e-76 254.3 0.9 9.7e-76 253.8 0.9 1.3 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.23 001266590.1_29625001_3 - 4e-07 29.8 0.1 7.8e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.7 001266590.1_29625001_3 - 2.8e-06 26.4 0.1 6.6e-06 25.1 0.1 1.6 1 1 0 1 1 1 1 Telomere regulation protein Stn1 STN1_2 PF09170.8 001243685.1_49824001_1 - 2.5e-73 245.9 0.6 2.5e-73 245.9 0.6 1.5 2 0 0 2 2 2 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.23 001243685.1_49824001_1 - 1.4e-07 31.2 0.1 3e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.7 001243685.1_49824001_1 - 2.3e-07 29.9 0.1 4.5e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 Telomere regulation protein Stn1 Hrs_helical PF12210.6 001243685.1_49824001_1 - 0.12 12.8 0.1 0.41 11.1 0.1 1.9 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate ELM2 PF01448.22 001169116.2_45729001_2 - 3e-08 34.1 1.1 6.4e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.29 001169116.2_45729001_2 - 0.00084 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-UBP PF02148.17 001169116.2_45729001_2 - 0.05 13.8 0.5 0.14 12.3 0.1 1.8 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2 PF00096.24 001169116.2_45729001_2 - 0.066 13.6 2.0 0.2 12.1 2.0 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-Mss51 PF13824.4 001169116.2_45729001_2 - 0.078 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_4 PF13894.4 001169116.2_45729001_2 - 0.15 12.9 2.4 0.29 11.9 1.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger FAM35_C PF15793.3 001025028.2_45727001_1 - 1.9e-77 258.4 0.8 3.6e-77 257.6 0.8 1.5 1 0 0 1 1 1 1 Protein family FAM35, C-terminal 7tm_4 PF13853.4 001000549.1_45722001_1 - 2.5e-72 243.8 19.0 3e-72 243.5 19.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000549.1_45722001_1 - 2.2e-16 59.8 25.7 5.2e-15 55.3 25.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000549.1_45722001_1 - 1.9e-07 30.6 20.4 3.5e-07 29.8 20.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-C3HC4_2 PF13923.4 001106935.1_45723001_1 - 8.1e-11 41.4 10.7 1.4e-10 40.7 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.23 001106935.1_45723001_1 - 8.6e-09 35.0 12.7 1.5e-08 34.2 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.4 001106935.1_45723001_1 - 2.8e-06 27.4 11.0 5e-06 26.6 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.4 001106935.1_45723001_1 - 7.1e-06 25.8 7.9 1.7e-05 24.6 7.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.4 001106935.1_45723001_1 - 4.8e-05 23.1 11.7 9.4e-05 22.2 11.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.4 001106935.1_45723001_1 - 0.00018 21.2 9.4 0.0003 20.4 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.3 001106935.1_45723001_1 - 0.00077 19.4 5.9 0.0015 18.5 5.9 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.4 001106935.1_45723001_1 - 0.0018 18.3 9.6 0.0042 17.1 9.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.4 001106935.1_45723001_1 - 0.012 15.3 3.1 0.021 14.5 3.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.4 001106935.1_45723001_1 - 0.19 11.5 11.2 0.38 10.5 11.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.5 001106935.1_45723001_1 - 0.21 11.8 11.5 0.58 10.4 11.5 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.3 001106935.1_45723001_1 - 0.29 10.9 6.0 0.64 9.8 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.9 001106935.1_45723001_1 - 0.29 11.1 6.0 0.57 10.2 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.6 001106935.1_45723001_1 - 0.9 9.3 7.0 1.6 8.4 7.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.4 001106935.1_45723001_1 - 4.4 7.0 8.0 8.3 6.1 8.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Histone_H2A_C PF16211.3 001109423.1_45721001_1 - 8.5e-21 73.3 1.2 1.4e-20 72.5 1.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.22 001109423.1_45721001_1 - 5.1e-17 62.4 0.0 6.9e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.21 001109423.1_45721001_1 - 8.2e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Motilin_ghrelin PF04644.10 001163002.1_45722001_2 - 0.02 14.6 1.2 0.052 13.3 1.2 1.7 1 0 0 1 1 1 0 Motilin/ghrelin DUF4713 PF15831.3 001163002.1_45722001_3 - 7.6e-23 80.6 6.7 7.6e-23 80.6 6.7 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4713) ETAA1 PF15350.4 001109094.1_45727001_1 - 0 1054.0 38.4 0 1053.8 38.4 1.0 1 0 0 1 1 1 1 Ewing's tumour-associated antigen 1 homologue Lipocalin PF00061.21 001135809.1_45722001_1 - 4.5e-14 52.7 0.1 6e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Arrestin_N PF00339.27 001109408.1_45723001_1 - 1.7e-21 76.7 0.0 1.7e-20 73.4 0.0 2.3 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.20 001109408.1_45723001_1 - 2.2e-21 76.5 0.1 3.5e-17 62.9 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.8 001109408.1_45723001_1 - 0.00038 19.6 1.4 0.0044 16.1 0.3 2.1 1 1 1 2 2 2 2 Rgp1 Thrombin_light PF09396.8 001109408.1_45723001_3 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Thrombin light chain DUF4716 PF15837.3 001242633.1_45722001_3 - 1.1e-33 115.0 2.9 2.2e-33 114.0 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4716) PetN PF03742.12 001242633.1_45722001_3 - 0.075 12.8 1.6 0.15 11.9 1.6 1.4 1 0 0 1 1 1 0 PetN ASCH PF04266.12 001106212.1_45723001_3 - 0.00077 19.9 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 ASCH domain 7tm_4 PF13853.4 001000416.1_45722001_1 - 1.5e-50 172.4 14.7 1.9e-50 172.1 14.7 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000416.1_45722001_1 - 5.7e-22 78.1 11.0 7.8e-22 77.6 11.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000416.1_45722001_1 - 0.00028 20.2 14.9 0.00081 18.7 14.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx EF-hand_1 PF00036.30 001106930.1_45723001_3 - 1.6e-17 61.5 5.9 1.7e-06 27.0 0.6 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.4 001106930.1_45723001_3 - 3.5e-16 59.3 3.5 1.7e-11 44.3 1.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.4 001106930.1_45723001_3 - 1.3e-15 55.8 3.6 9.5e-06 25.0 0.2 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.4 001106930.1_45723001_3 - 1.5e-15 55.7 0.5 3.1e-06 26.3 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.4 001106930.1_45723001_3 - 1.5e-05 24.5 10.8 0.23 11.2 0.3 3.7 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001106930.1_45723001_3 - 0.019 15.1 0.6 7.5 6.8 0.2 2.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region 7tm_4 PF13853.4 001000485.1_45722001_1 - 5.7e-53 180.3 19.5 7e-53 180.0 19.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000485.1_45722001_1 - 2.8e-24 85.7 16.3 5e-24 84.8 16.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000485.1_45722001_1 - 9.5e-08 31.6 15.0 1.5e-07 30.9 15.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Claudin_2 PF13903.4 001109366.1_45722001_1 - 7.3e-08 32.3 10.4 1.2e-07 31.6 10.4 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.18 001109366.1_45722001_1 - 5.5e-06 26.2 9.5 8.9e-06 25.5 9.5 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family MHYT PF03707.14 001109366.1_45722001_1 - 2.8 8.0 11.3 0.71 9.9 0.6 3.8 3 1 1 4 4 4 0 Bacterial signalling protein N terminal repeat 7tm_4 PF13853.4 001000399.1_45722001_1 - 9.2e-54 182.9 15.9 1.2e-53 182.5 15.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000399.1_45722001_1 - 6.7e-29 100.8 16.4 1.3e-28 99.9 16.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TPR_2 PF07719.15 001106706.1_45726001_3 - 1.3e-15 56.0 15.5 0.00014 21.5 0.0 7.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.26 001106706.1_45726001_3 - 8.2e-14 50.6 6.5 0.00067 19.2 0.0 6.2 8 0 0 8 8 5 3 Tetratricopeptide repeat TPR_14 PF13428.4 001106706.1_45726001_3 - 3.5e-12 45.9 1.9 0.03 15.0 0.0 7.4 5 3 3 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.4 001106706.1_45726001_3 - 4e-11 42.1 7.5 0.00033 20.5 0.0 6.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.4 001106706.1_45726001_3 - 5e-10 39.3 0.0 5e-06 26.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.4 001106706.1_45726001_3 - 4.7e-09 35.9 0.1 0.00029 20.9 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.4 001106706.1_45726001_3 - 8.5e-08 32.5 0.2 0.0024 18.2 0.0 5.6 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.4 001106706.1_45726001_3 - 1.4e-07 31.9 0.0 0.0004 20.9 0.0 4.3 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.4 001106706.1_45726001_3 - 1.9e-07 30.5 0.0 0.0057 16.2 0.1 4.4 3 1 1 4 4 4 2 TPR repeat ANAPC3 PF12895.5 001106706.1_45726001_3 - 1.4e-06 28.2 5.8 0.024 14.7 0.3 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.4 001106706.1_45726001_3 - 1.2e-05 25.4 9.4 1.1 9.5 0.1 6.9 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.4 001106706.1_45726001_3 - 6.2e-05 22.6 2.0 12 6.1 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.4 001106706.1_45726001_3 - 0.00068 20.0 0.3 14 6.4 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.8 001106706.1_45726001_3 - 0.0081 15.1 0.0 1.6 7.5 0.1 2.3 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.4 001106706.1_45726001_3 - 0.041 13.8 0.4 6.5 6.8 0.0 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.4 001106706.1_45726001_3 - 0.063 12.4 1.5 0.36 9.8 0.2 2.7 2 1 0 3 3 3 0 Tetratricopeptide repeat Cortexin PF11057.6 001162935.1_45721001_1 - 1.9e-40 136.5 0.0 2.8e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 Cortexin of kidney KH_1 PF00013.27 001106968.1_45725001_1 - 2.2e-52 174.6 5.8 6.9e-11 41.7 0.2 7.9 7 1 0 7 7 7 7 KH domain SLS PF14611.4 001106968.1_45725001_1 - 0.0016 18.2 3.6 0.17 11.5 0.1 4.5 3 2 1 4 4 4 1 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.4 001106968.1_45725001_1 - 0.0082 16.1 0.1 7.5 6.6 0.0 3.1 2 0 0 2 2 2 2 NusA-like KH domain DUF4549 PF15082.4 001106968.1_45725001_1 - 0.028 14.2 0.5 1.3 8.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) FAD_binding_9 PF08021.9 001106968.1_45725001_1 - 0.15 12.2 0.1 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain zf-H2C2_2 PF13465.4 001134998.1_45724001_1 - 2.8e-05 24.2 16.3 0.004 17.4 0.7 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.24 001134998.1_45724001_1 - 0.00024 21.2 10.3 0.011 16.0 0.1 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type Baculo_LEF-11 PF06385.10 001134998.1_45724001_1 - 2.7 8.4 7.7 11 6.5 0.2 4.1 2 2 2 4 4 4 0 Baculovirus LEF-11 protein zf-C2H2_4 PF13894.4 001134998.1_45724001_1 - 8.2 7.4 9.7 14 6.7 0.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.4 001134998.1_45724001_3 - 6.7e-65 212.7 91.5 1.4e-08 34.6 1.0 12.1 12 0 0 12 12 12 8 Zinc-finger double domain zf-C2H2 PF00096.24 001134998.1_45724001_3 - 1.5e-34 116.4 84.3 7.7e-07 29.1 0.7 10.0 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.4 001134998.1_45724001_3 - 4.1e-25 86.1 94.4 0.00021 21.7 0.5 11.3 11 0 0 11 11 11 8 C2H2-type zinc finger KRAB PF01352.25 001134998.1_45724001_3 - 1.6e-21 75.5 0.0 3.2e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_6 PF13912.4 001134998.1_45724001_3 - 7.4e-19 67.1 84.2 9.5e-07 28.5 3.1 10.8 11 0 0 11 11 11 7 C2H2-type zinc finger GATA PF00320.25 001134998.1_45724001_3 - 1.9e-05 24.1 26.2 1.1 8.9 0.2 8.7 8 0 0 8 8 8 1 GATA zinc finger zf-C2H2_11 PF16622.3 001134998.1_45724001_3 - 0.00015 21.3 41.3 0.46 10.2 0.2 8.4 8 0 0 8 8 8 5 zinc-finger C2H2-type Zn-ribbon_8 PF09723.8 001134998.1_45724001_3 - 0.00016 21.6 50.4 0.009 16.0 1.5 7.3 4 2 5 9 9 9 5 Zinc ribbon domain zf-C2H2_jaz PF12171.6 001134998.1_45724001_3 - 0.00072 19.7 9.9 0.0036 17.4 3.5 9.6 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.4 001134998.1_45724001_3 - 0.0062 16.3 29.2 1.7 8.4 0.1 8.0 7 1 0 7 7 7 1 Probable zinc-ribbon domain TrmE_N PF10396.7 001134998.1_45724001_3 - 0.026 14.7 0.1 0.94 9.7 0.0 3.1 2 1 0 3 3 3 0 GTP-binding protein TrmE N-terminus XPA_N PF01286.16 001134998.1_45724001_3 - 0.16 11.9 27.5 6.6 6.7 0.3 8.2 8 0 0 8 8 8 0 XPA protein N-terminal zinc_ribbon_15 PF17032.3 001134998.1_45724001_3 - 0.44 11.2 46.2 1.7 9.3 3.2 5.3 1 1 5 6 6 6 0 zinc-ribbon family zf-C2HE PF16278.3 001134998.1_45724001_3 - 3.3 8.1 63.6 2.4 8.6 2.6 9.0 1 1 7 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.9 001134998.1_45724001_3 - 4.4 7.2 44.7 3.1 7.7 1.1 9.0 8 0 0 8 8 8 0 LYAR-type C2HC zinc finger Sulfotransfer_1 PF00685.25 001192017.1_45723001_1 - 9.6e-55 185.8 0.1 1.4e-54 185.2 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.4 001192017.1_45723001_1 - 4.8e-05 23.7 0.0 8.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family FUN14 PF04930.13 001014251.1_45725001_2 - 1e-25 89.8 4.0 1.7e-25 89.1 4.0 1.4 1 0 0 1 1 1 1 FUN14 family zf-DHHC PF01529.18 001039333.1_45723001_2 - 3.2e-34 117.8 2.4 3.2e-34 117.8 2.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.5 001039333.1_45723001_2 - 0.41 10.6 8.1 1.2 9.1 8.1 1.8 1 0 0 1 1 1 0 Double zinc ribbon 7tm_4 PF13853.4 001001362.1_45722001_1 - 2.3e-49 168.5 21.3 2.9e-49 168.2 21.3 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001362.1_45722001_1 - 1.2e-22 80.3 21.1 2.8e-22 79.1 21.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2976 PF11190.6 001001362.1_45722001_1 - 0.026 14.2 0.9 0.073 12.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF3810 PF12725.5 001001362.1_45722001_1 - 0.53 9.4 11.2 0.084 12.1 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) LEP503 PF15221.4 001110138.1_45726001_1 - 3.3e-33 113.5 8.2 5.3e-33 112.8 1.5 2.6 2 0 0 2 2 2 2 Lens epithelial cell protein LEP503 MoCF_biosynth PF00994.22 001110138.1_45726001_2 - 4.3e-28 97.6 0.0 7.1e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.17 001110138.1_45726001_2 - 7.8e-25 87.8 0.0 2.9e-22 79.4 0.0 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Acetyltransf_3 PF13302.5 001134835.1_45723001_1 - 2e-24 86.7 0.1 5e-24 85.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.23 001134835.1_45723001_1 - 2.2e-06 27.7 0.0 3.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.8 001134835.1_45723001_1 - 6.1e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.4 001134835.1_45723001_1 - 0.004 16.7 0.1 0.016 14.8 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.5 001134835.1_45723001_1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.5 001134835.1_45723001_1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hormone_1 PF00103.18 001044702.1_45722001_1 - 3e-33 115.3 0.5 3.7e-33 115.0 0.5 1.0 1 0 0 1 1 1 1 Somatotropin hormone family HHH PF00633.21 001044702.1_45722001_1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Claudin_2 PF13903.4 001109402.1_45723001_3 - 6.5e-12 45.5 0.8 8.3e-12 45.1 0.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.18 001109402.1_45723001_3 - 2.4e-07 30.7 0.6 3.6e-07 30.1 0.6 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Ank_2 PF12796.5 001108231.1_45724001_1 - 1.3e-23 83.2 6.6 3.6e-09 36.9 0.1 4.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001108231.1_45724001_1 - 2.4e-20 72.5 8.1 7e-09 35.9 0.4 6.0 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.28 001108231.1_45724001_1 - 3.3e-20 71.4 18.5 0.0028 17.9 0.4 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.4 001108231.1_45724001_1 - 1.2e-17 63.6 14.2 0.00013 22.1 0.2 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.4 001108231.1_45724001_1 - 1e-15 56.1 7.7 0.0047 17.2 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat SOCS_box PF07525.14 001108231.1_45724001_1 - 6.2e-12 45.5 4.6 6.2e-12 45.5 4.6 2.5 2 0 0 2 2 2 1 SOCS box SH2 PF00017.22 001108223.1_45723001_1 - 6.3e-14 51.7 0.0 9.7e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 SH2 domain 7tm_4 PF13853.4 001001018.1_45722001_1 - 1.7e-48 165.6 16.3 2.1e-48 165.4 16.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001001018.1_45722001_1 - 2.9e-25 88.9 19.2 6.5e-25 87.7 19.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001001018.1_45722001_1 - 5.4e-07 29.1 15.9 7.3e-07 28.7 15.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Lipocalin PF00061.21 001024248.1_45722001_1 - 2.7e-31 108.6 0.7 3.1e-31 108.4 0.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family RRM_1 PF00076.20 001106429.1_45723001_2 - 1.2e-80 265.1 5.8 2.3e-20 72.0 0.1 4.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001106429.1_45723001_2 - 1.5e-12 47.0 1.3 0.02 14.4 0.0 4.1 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.4 001106429.1_45723001_2 - 3.5e-08 33.1 0.1 0.018 14.9 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.11 001106429.1_45723001_2 - 3.1e-06 26.9 0.1 0.0013 18.5 0.0 3.7 3 1 1 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.3 001106429.1_45723001_2 - 9.1e-06 25.6 0.4 2.4 8.2 0.0 4.7 4 2 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.3 001106429.1_45723001_2 - 2.8e-05 23.8 0.1 2.1 8.1 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.6 001106429.1_45723001_2 - 9.6e-05 22.3 0.5 0.21 11.6 0.2 3.6 4 0 0 4 4 4 1 Limkain b1 RRM_3 PF08777.9 001106429.1_45723001_2 - 0.045 13.7 5.2 0.83 9.6 1.5 3.9 3 1 1 4 4 4 0 RNA binding motif DUF4523 PF15023.4 001106429.1_45723001_2 - 0.055 13.2 0.1 8.2 6.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4523) SET_assoc PF11767.6 001106429.1_45723001_2 - 0.1 12.1 0.0 35 4.0 0.0 3.5 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated DNA_ligase_IV PF11411.6 001106429.1_45723001_2 - 0.14 12.1 2.8 5.4 7.1 0.0 2.9 3 0 0 3 3 3 0 DNA ligase IV Yip1 PF04893.15 001108861.1_45723001_1 - 6.2e-11 42.2 13.1 9.4e-11 41.6 13.1 1.3 1 0 0 1 1 1 1 Yip1 domain 7tm_3 PF00003.20 001099469.1_45726001_1 - 3.1e-56 190.7 24.3 7.3e-56 189.4 24.3 1.6 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.26 001099469.1_45726001_1 - 1.6e-37 129.3 0.0 2.5e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.12 001099469.1_45726001_1 - 1.9e-19 69.3 14.6 3.7e-19 68.3 14.6 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR PAP2_C PF14360.4 001099469.1_45726001_1 - 5.9 7.3 10.6 0.39 11.1 2.3 3.2 2 0 0 2 2 2 0 PAP2 superfamily C-terminal F-box-like PF12937.5 001013132.2_45723001_3 - 1e-09 38.0 4.0 2.1e-09 37.0 4.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.31 001013132.2_45723001_3 - 1.1e-07 31.4 1.9 2.9e-07 30.0 1.9 1.7 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.5 001108420.1_45724001_3 - 8.9e-38 128.6 12.4 2e-14 53.8 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001108420.1_45724001_3 - 9.8e-34 115.2 12.1 2.5e-10 40.5 0.1 4.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.28 001108420.1_45724001_3 - 1.5e-33 113.6 12.5 8.7e-06 25.8 0.5 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.4 001108420.1_45724001_3 - 2.6e-24 82.5 5.6 0.00028 21.0 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.4 001108420.1_45724001_3 - 2.4e-22 78.5 10.1 2.1e-06 27.8 0.1 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.14 001108420.1_45724001_3 - 3.3e-09 36.8 0.3 6.5e-09 35.9 0.3 1.5 1 0 0 1 1 1 1 SOCS box Trypsin PF00089.24 001109156.1_45724001_2 - 2.4e-68 230.1 0.0 7.7e-43 146.7 0.1 2.1 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.9 001109156.1_45724001_2 - 8.5e-11 42.1 0.1 9.7e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin_2 PF13365.4 001109156.1_45724001_2 - 3.2e-07 31.2 0.5 7.8e-05 23.4 0.2 3.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain Fer4_2 PF12797.5 001109156.1_45724001_2 - 4.5 7.4 7.2 16 5.7 2.0 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Trypsin PF00089.24 001109156.1_45724001_3 - 0.00031 20.5 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin 7tm_4 PF13853.4 001000736.1_45722001_1 - 6.8e-48 163.7 13.4 8.9e-48 163.3 13.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000736.1_45722001_1 - 1.5e-24 86.5 12.0 2.7e-24 85.7 12.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000736.1_45722001_1 - 3.7e-05 23.1 9.7 5e-05 22.7 9.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FAM196 PF15265.4 001143803.1_45729001_2 - 1e-202 674.9 9.7 1.4e-202 674.4 9.7 1.2 1 0 0 1 1 1 1 FAM196 family Cadherin PF00028.15 001009448.1_45725001_1 - 2e-67 223.6 11.3 4.7e-16 58.9 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.15 001009448.1_45725001_1 - 3.5e-46 156.6 2.2 7.4e-46 155.6 0.3 2.4 3 0 0 3 3 3 1 Cadherin cytoplasmic region Cadherin_2 PF08266.10 001009448.1_45725001_1 - 4e-09 36.0 0.1 0.0034 17.0 0.0 4.8 5 0 0 5 5 5 2 Cadherin-like 7tm_4 PF13853.4 001000196.1_45722001_1 - 5.9e-52 177.0 18.1 7.6e-52 176.6 18.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000196.1_45722001_1 - 2.4e-27 95.7 20.4 2e-26 92.7 20.4 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000196.1_45722001_1 - 7e-09 35.3 19.6 1.3e-08 34.5 19.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4577 PF15145.4 001000196.1_45722001_1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) FAM117 PF15388.4 001109039.1_45725001_3 - 2.8e-112 374.9 4.4 3.8e-112 374.5 4.4 1.2 1 0 0 1 1 1 1 Protein Family FAM117 DUF1725 PF08333.9 001177816.1_45724001_1 - 8.8e-09 34.6 2.7 1.6e-08 33.8 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1725) Cadherin PF00028.15 001169129.1_45729001_1 - 1.8e-87 287.8 0.6 6.2e-20 71.3 0.0 6.5 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.10 001169129.1_45729001_1 - 8.4e-20 70.3 0.2 1.7e-17 62.9 0.0 3.6 4 0 0 4 4 4 1 Cadherin-like Cadherin_C_2 PF16492.3 001169129.1_45729001_1 - 0.0016 19.1 0.5 0.0058 17.3 0.5 2.1 1 1 0 1 1 1 1 Cadherin cytoplasmic C-terminal PepSY PF03413.17 001169129.1_45729001_1 - 0.021 15.2 2.2 6.6 7.3 0.3 3.6 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Cwf_Cwc_15 PF04889.10 001287621.1_45721001_1 - 0.05 13.2 9.5 0.06 12.9 9.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.11 001287621.1_45721001_1 - 0.12 12.3 5.4 0.13 12.2 5.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.11 001287621.1_45721001_1 - 0.34 8.9 6.4 0.32 8.9 6.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.9 001287621.1_45721001_1 - 0.42 9.0 3.5 0.41 9.0 3.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.10 001287621.1_45721001_1 - 1.4 8.1 13.8 1.8 7.8 13.8 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.4 001287621.1_45721001_1 - 1.7 9.0 10.8 2.6 8.4 10.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.12 001287621.1_45721001_1 - 4.6 5.3 8.2 5.2 5.1 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.8 001287621.1_45721001_1 - 6.5 7.1 15.7 10 6.5 15.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Baculo_11_kDa PF06143.9 001287621.1_45721001_2 - 0.091 12.2 7.7 0.18 11.3 7.7 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family MFS_1 PF07690.14 001108215.1_45727001_3 - 3.6e-38 131.3 26.7 7.5e-38 130.2 26.7 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.22 001108215.1_45727001_3 - 4e-06 25.8 9.8 4e-06 25.8 9.8 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.5 001108215.1_45727001_3 - 1.5e-05 23.9 13.9 0.00021 20.2 13.9 2.2 1 1 0 1 1 1 1 MFS_1 like family Keratin_B2_2 PF13885.4 001271304.1_45721001_1 - 6e-10 38.8 117.3 1.6e-05 24.6 44.7 3.6 1 1 2 3 3 3 3 Keratin, high sulfur B2 protein Keratin_B2 PF01500.15 001271304.1_45721001_1 - 0.19 11.6 81.8 0.2 11.5 38.2 2.2 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein PMG PF05287.10 001271304.1_45721001_1 - 1.1 9.1 64.0 7.2 6.5 33.6 2.3 1 1 0 1 1 1 0 PMG protein 7tm_4 PF13853.4 001000400.1_45722001_1 - 1.2e-52 179.3 20.8 1.4e-52 179.0 20.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000400.1_45722001_1 - 1.9e-22 79.7 20.0 3.6e-22 78.7 20.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 001000400.1_45722001_1 - 0.00036 19.9 19.8 0.0018 17.6 19.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Pox_A14 PF05767.10 001000400.1_45722001_1 - 3.1 7.9 9.4 0.45 10.6 3.1 2.7 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 THEG4 PF15834.3 001109566.1_45722001_3 - 1.7e-111 370.8 0.5 2e-111 370.6 0.5 1.1 1 0 0 1 1 1 1 Testis highly expressed protein 4 YSIRK_signal PF04650.15 001109566.1_45722001_3 - 0.09 12.5 1.4 0.15 11.8 1.4 1.4 1 0 0 1 1 1 0 YSIRK type signal peptide DUF4633 PF15464.4 001109521.1_45723001_1 - 2.4e-54 182.2 9.3 3.8e-54 181.6 9.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4633) 7tm_1 PF00001.19 001107677.1_45723001_3 - 8.6e-37 126.7 18.1 1.2e-36 126.2 18.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Alg14 PF08660.9 001107677.1_45723001_3 - 0.025 14.4 0.7 0.056 13.2 0.7 1.6 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like 7tm_4 PF13853.4 001000705.1_45722001_1 - 1.5e-49 169.1 21.1 1.9e-49 168.7 21.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.19 001000705.1_45722001_1 - 1.2e-23 83.6 23.7 3.5e-23 82.1 23.7 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3810 PF12725.5 001000705.1_45722001_1 - 7.6 5.6 10.6 6.9 5.8 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) VlpA_repeat PF04649.10 131086.1_45722120_1 - 0.8 9.9 4.3 1.7 8.9 1.1 2.6 2 0 0 2 2 2 0 Mycoplasma hyorhinis VlpA repeat DUF3678 PF12435.6 130765.1_26224120_3 - 0.92 8.7 3.9 0.29 10.3 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) GPS PF01825.19 132626.1_45724120_1 - 6.1 7.5 6.5 1.3 9.6 2.3 2.0 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif DUF4567 PF15131.4 132626.1_45724120_3 - 1.9e-34 117.6 0.4 3.4e-34 116.9 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4567) CHCH PF06747.11 028321.1_45726120_1 - 7e-09 35.5 5.9 7e-09 35.5 5.9 2.1 2 0 0 2 2 2 1 CHCH domain MHC_I PF00129.16 002597.1_45724120_1 - 3.7e-15 55.8 0.1 5.3e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I PF00129.16 002597.1_45724120_2 - 1.7e-23 82.9 6.9 5.8e-23 81.2 6.9 1.8 1 1 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.13 002597.1_45724120_2 - 9.7e-16 57.9 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.4 002597.1_45724120_2 - 6.7e-05 23.3 0.5 0.0028 18.1 0.1 2.4 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.23 002597.1_45724120_2 - 0.00039 20.4 0.0 0.00073 19.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.10 002597.1_45724120_2 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.4 002597.1_45724120_2 - 0.071 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain P12 PF12669.5 002597.1_45724120_2 - 5.3 7.4 7.1 0.24 11.7 0.6 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family Ribosomal_S4e PF00900.18 131253.1_45723120_1 - 0.00038 20.2 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.3 131253.1_45723120_2 - 2.1e-25 88.0 0.1 3.2e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus Ribosomal_S4e PF00900.18 131253.1_45723120_2 - 0.0017 18.1 0.0 0.0059 16.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.10 131253.1_45723120_3 - 1.8e-13 50.2 0.2 3.9e-13 49.1 0.2 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain Ribosomal_S4e PF00900.18 131253.1_45723120_3 - 6.8e-12 45.0 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal family S4e S4 PF01479.23 131253.1_45723120_3 - 0.055 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 S4 domain zf-RING_10 PF16685.3 102352.1_45722120_1 - 0.0069 16.4 2.2 0.021 14.8 0.5 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 DUF4730 PF15873.3 110645.1_45722120_1 - 1.9e-25 88.7 5.2 1.9e-25 88.7 5.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4730) T2SSF PF00482.21 131133.1_45721120_2 - 0.14 12.0 0.3 0.18 11.6 0.3 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF4560 PF15118.4 110728.1_45726120_1 - 2.8e-23 81.6 0.1 5.8e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4560) PalH PF08733.8 132636.1_45723120_1 - 0.01 14.7 2.2 0.013 14.4 2.2 1.1 1 0 0 1 1 1 0 PalH/RIM21 DUF2070 PF09843.7 132636.1_45723120_1 - 0.2 9.8 2.8 0.25 9.4 2.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ODV-E18 PF10717.7 132636.1_45723120_1 - 0.31 10.8 6.4 0.37 10.6 5.2 1.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Ferlin_C PF16165.3 132636.1_45723120_1 - 6 6.7 7.5 10 5.9 7.5 1.2 1 0 0 1 1 1 0 Ferlin C-terminus DUF929 PF06053.9 132636.1_45723120_1 - 7.2 5.7 7.8 9.8 5.3 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) FAM91_N PF14647.4 111950.1_26229120_1 - 1.1e-71 241.6 0.0 1.8e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.4 111950.1_26229120_1 - 1.8e-06 26.9 0.0 2.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_C PF14648.4 111950.1_26229120_2 - 2.4e-10 39.7 0.7 1.2e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 FAM91 C-terminus FAM91_N PF14647.4 111950.1_26229120_2 - 0.0014 17.8 0.2 0.0021 17.3 0.2 1.1 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.4 111950.1_26229120_3 - 3.9e-102 342.1 4.1 6.4e-83 278.8 0.0 3.1 2 1 1 3 3 3 3 FAM91 C-terminus FAM91_N PF14647.4 111950.1_26229120_3 - 5.6e-18 65.1 0.1 8.4e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 FAM91 N-terminus zf-RING_10 PF16685.3 102351.1_45722120_1 - 0.012 15.6 2.2 0.028 14.4 0.5 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 TLV_coat PF00429.17 131094.1_45726120_2 - 2e-12 46.5 6.2 7.2e-08 31.4 0.1 2.8 3 0 0 3 3 3 2 ENV polyprotein (coat polyprotein) 7tm_1 PF00001.19 111000.1_26225120_2 - 6e-34 117.4 4.5 6e-34 117.4 4.5 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.7 111000.1_26225120_2 - 0.0053 16.0 1.9 0.0054 16.0 0.2 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.7 111000.1_26225120_2 - 0.096 11.9 5.2 0.11 11.7 0.0 2.7 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx zf-LITAF-like PF10601.7 111000.1_26225120_2 - 2 8.6 10.5 5.4 7.2 2.8 2.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain 7tm_1 PF00001.19 111000.1_26225120_3 - 7.1e-18 64.7 3.3 9.4e-18 64.3 3.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF913 PF06025.10 001266752.1_29629001_3 - 1.3e-115 386.1 0.1 1.3e-115 386.1 0.1 6.0 7 0 0 7 7 7 1 Domain of Unknown Function (DUF913) HECT PF00632.23 001266752.1_29629001_3 - 3.6e-94 315.6 0.5 5.9e-94 314.9 0.5 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.4 001266752.1_29629001_3 - 2.8e-28 98.4 2.8 2.8e-28 98.4 2.8 6.5 7 1 1 8 8 8 1 Domain of unknown function (DUF4414) DUF908 PF06012.10 001266752.1_29629001_3 - 9.4e-28 97.5 8.2 9.4e-28 97.5 8.2 7.2 7 2 0 7 7 7 1 Domain of Unknown Function (DUF908) WWE PF02825.18 001266752.1_29629001_3 - 2.8e-13 50.1 2.2 8.7e-13 48.5 2.2 1.9 1 0 0 1 1 1 1 WWE domain UBA PF00627.29 001266752.1_29629001_3 - 3.7e-07 29.8 0.7 9.3e-07 28.5 0.7 1.8 1 0 0 1 1 1 1 UBA/TS-N domain FdhE PF04216.10 001266752.1_29629001_3 - 1.8 8.2 8.8 8.1 6.1 0.5 3.0 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation zf-CCCH PF00642.22 001318118.1_45727001_3 - 1.2e-20 72.8 18.9 3.4e-10 39.5 5.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.3 001318118.1_45727001_3 - 0.014 15.9 10.5 0.25 11.9 1.8 2.3 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.4 001318118.1_45727001_3 - 0.44 11.0 15.1 3.9 8.0 1.8 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Proteasome PF00227.24 001329883.1_45722001_1 - 3e-46 157.2 0.2 3.4e-46 157.0 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit cobW PF02492.17 138473.1_26224120_2 - 1.8e-48 164.4 0.0 2.5e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.12 138473.1_26224120_2 - 1.2e-16 60.2 0.0 2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DUF258 PF03193.14 138473.1_26224120_2 - 0.0001 22.1 0.2 0.052 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.4 138473.1_26224120_2 - 0.012 16.1 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.25 138473.1_26224120_2 - 0.027 13.9 0.2 5.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.7 138473.1_26224120_2 - 0.034 12.8 0.0 0.061 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_16 PF13191.4 138473.1_26224120_2 - 0.04 14.2 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.25 138473.1_26224120_2 - 0.069 13.5 0.1 0.17 12.3 0.1 1.8 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.15 138473.1_26224120_2 - 0.07 13.0 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.21 138473.1_26224120_2 - 0.092 12.7 0.1 0.31 11.0 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.10 138473.1_26224120_2 - 0.14 11.3 0.0 0.29 10.3 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.4 138473.1_26224120_2 - 0.16 11.5 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Anth_Ig PF05587.11 134500.1_26222120_2 - 2e-05 24.9 2.0 0.00015 22.0 0.1 2.4 3 0 0 3 3 3 1 Anthrax receptor extracellular domain NPIP PF06409.9 136612.1_26227120_1 - 4.5e-08 32.5 2.4 7.9e-08 31.7 2.4 1.3 1 0 0 1 1 1 1 Nuclear pore complex interacting protein (NPIP) ERO1 PF04137.13 001280454.1_39724001_3 - 2.9e-127 424.6 0.0 3.4e-127 424.3 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Cystatin PF00031.19 144435.1_45721120_2 - 2.2e-08 34.1 0.0 2.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain Ribosomal_S5 PF00333.18 144446.1_45723120_1 - 1.7e-24 85.4 0.9 8e-24 83.3 0.9 2.0 1 1 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.13 144446.1_45723120_1 - 3e-18 64.9 0.1 4.8e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain IQ PF00612.25 001014271.1_45724001_2 - 0.00012 21.5 1.0 0.00012 21.5 1.0 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif PRESAN PF09687.8 001014271.1_45724001_2 - 0.0068 16.8 1.6 0.11 13.0 0.0 3.1 3 0 0 3 3 3 1 Plasmodium RESA N-terminal BTB PF00651.29 001100985.1_45724001_2 - 3e-29 101.4 0.3 9.4e-29 99.7 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain HECT PF00632.23 001195340.1_49828001_2 - 1.5e-91 307.0 0.0 7.7e-91 304.6 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.5 001195340.1_49828001_2 - 3.8e-34 117.0 2.6 2.8e-11 43.7 0.4 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.4 001195340.1_49828001_2 - 1.3e-32 111.6 2.6 4.5e-11 42.9 0.1 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.4 001195340.1_49828001_2 - 1.1e-26 89.8 2.7 1.7e-05 24.7 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.28 001195340.1_49828001_2 - 9.7e-26 88.9 11.4 5e-06 26.6 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.4 001195340.1_49828001_2 - 3e-22 78.2 7.0 4.4e-08 33.1 0.1 4.4 1 1 2 4 4 4 4 Ankyrin repeats (many copies) HECT PF00632.23 001257631.1_29629001_3 - 2.7e-101 339.0 0.0 3.4e-101 338.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.24 001257631.1_29629001_3 - 1.8e-16 59.6 3.4 4.4e-08 32.8 0.1 2.7 2 0 0 2 2 2 2 WW domain C2 PF00168.28 001257631.1_29629001_3 - 9.2e-16 57.9 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain HPS3_N PF14761.4 001257631.1_29629001_3 - 0.12 11.9 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 HECT PF00632.23 001260910.1_29629001_2 - 1.1e-78 264.7 0.3 1.6e-78 264.2 0.3 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.17 001260910.1_29629001_2 - 7.7e-10 39.4 0.5 1.7e-07 31.8 0.0 2.9 3 0 0 3 3 3 2 Filamin/ABP280 repeat T4_deiodinase PF00837.15 001122651.3_39724001_3 - 3.4e-101 337.3 0.1 4.6e-101 336.9 0.1 1.2 1 0 0 1 1 1 1 Iodothyronine deiodinase HECT PF00632.23 001265810.1_29629001_2 - 2.3e-106 355.6 0.0 3.4e-106 355.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.3 001265810.1_29629001_2 - 5.5e-59 197.1 0.5 1e-58 196.2 0.5 1.5 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 WW PF00397.24 001265810.1_29629001_2 - 2.6e-18 65.5 0.5 3e-10 39.7 0.6 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.28 001265810.1_29629001_2 - 1.7e-11 44.2 0.0 5.5e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain Keratin_B2_2 PF13885.4 001265810.1_29629001_2 - 0.46 10.3 31.4 1.2 9.0 31.4 1.7 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein MRP PF09387.8 001346534.1_39728001_2 - 6.3e-95 316.6 1.0 1.1e-94 315.8 1.0 1.4 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Sad1_UNC PF07738.11 001346534.1_39728001_2 - 3.3e-47 159.8 0.0 6.8e-47 158.7 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Mnd1 PF03962.13 001346534.1_39728001_2 - 0.015 15.1 2.4 0.03 14.1 2.4 1.4 1 0 0 1 1 1 0 Mnd1 family CCDC144C PF14915.4 001346534.1_39728001_2 - 0.02 13.9 3.9 0.065 12.2 3.8 1.6 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Apolipoprotein PF01442.16 001346534.1_39728001_2 - 0.035 13.9 2.7 0.12 12.2 2.5 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ZapB PF06005.10 001346534.1_39728001_2 - 0.037 14.3 1.3 14 6.1 0.0 2.7 1 1 1 2 2 2 0 Cell division protein ZapB GrpE PF01025.17 001346534.1_39728001_2 - 0.066 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 GrpE VPS53_C PF16854.3 001346534.1_39728001_2 - 0.16 11.7 0.7 0.28 10.9 0.7 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus JIP_LZII PF16471.3 001346534.1_39728001_2 - 0.28 11.2 3.6 0.51 10.4 1.5 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II NPV_P10 PF05531.10 001346534.1_39728001_2 - 0.38 11.1 2.3 6.7 7.1 0.0 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NUP50 PF08911.9 144449.1_45724120_2 - 1.3e-13 51.1 2.5 3.5e-13 49.8 2.5 1.7 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.16 144449.1_45724120_2 - 1.9e-09 37.7 0.0 3.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Ran_BP1 PF00638.16 144449.1_45724120_3 - 4.8e-08 33.1 0.0 8.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain SAICAR_synt PF01259.16 001319546.1_29524001_1 - 7.9e-56 189.3 0.0 1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.18 001319546.1_29524001_1 - 2.4e-38 130.9 0.0 4.4e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 AIR carboxylase T4_deiodinase PF00837.15 001001625.2_49825001_1 - 5.3e-118 392.4 0.0 6.6e-118 392.0 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase T4_deiodinase PF00837.15 001257977.1_09922001_1 - 9.9e-111 368.6 0.0 1.2e-110 368.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase AhpC-TSA PF00578.19 001257977.1_09922001_1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family T4_deiodinase PF00837.15 001122637.3_39729001_3 - 2.1e-107 357.7 0.4 5.7e-83 277.7 0.0 2.2 2 0 0 2 2 2 2 Iodothyronine deiodinase T4_deiodinase PF00837.15 001122638.3_39729001_3 - 7.1e-114 378.8 0.0 1e-113 378.4 0.0 1.2 1 0 0 1 1 1 1 Iodothyronine deiodinase Phosphorylase PF00343.18 001168998.1_40426001_1 - 0 1162.3 0.0 0 1162.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase COX_ARM PF06481.12 001168998.1_40426001_1 - 0.015 15.0 0.7 0.046 13.5 0.1 2.1 2 0 0 2 2 2 0 COX Aromatic Rich Motif Rsa3 PF14615.4 001168998.1_40426001_1 - 0.031 13.7 0.8 2.8 7.5 0.0 2.7 2 0 0 2 2 2 0 Ribosome-assembly protein 3 T4_deiodinase PF00837.15 001256300.1_37925001_2 - 7e-112 372.3 0.0 8.7e-112 372.0 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase T4_deiodinase PF00837.15 001257974.1_09922001_1 - 8.7e-97 322.9 0.0 1e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Phosphorylase PF00343.18 001123172.1_49826001_1 - 0 1153.2 0.0 0 1153.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase zf-RVT PF13966.4 001271674.1_39726001_1 - 4.7 8.0 9.9 1.8 9.3 3.2 3.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase SprT-like PF10263.7 001271674.1_39726001_3 - 5.5e-26 91.1 2.1 9.8e-26 90.3 2.1 1.4 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.17 001271674.1_39726001_3 - 0.0025 18.0 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box zinc_ribbon_10 PF10058.7 001271674.1_39726001_3 - 0.045 13.3 1.4 0.12 12.0 1.4 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein V-set_2 PF15910.3 001042641.2_29622001_2 - 2.3e-13 50.1 1.0 3.2e-13 49.6 1.0 1.2 1 0 0 1 1 1 1 ICOS V-set domain V-set PF07686.15 001042641.2_29622001_2 - 7e-06 26.0 0.3 1.2e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Syndecan PF01034.18 001042641.2_29622001_2 - 0.16 11.8 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Connexin PF00029.17 001199049.1_37923001_1 - 7.8e-100 333.1 0.4 1.5e-99 332.3 0.4 1.4 1 0 0 1 1 1 1 Connexin TLP-20 PF06088.9 001199049.1_37923001_1 - 0.031 14.0 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Connexin40_C PF16791.3 001199049.1_37923001_1 - 0.11 13.6 0.3 0.11 13.6 0.3 2.1 2 0 0 2 2 2 0 Connexin 40 C-terminal domain Ribosomal_L18 PF17135.2 001193563.1_29622001_1 - 2.4e-95 317.1 4.1 2.7e-95 317.0 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.17 001193563.1_29622001_1 - 0.073 13.6 0.0 0.12 12.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A cobW PF02492.17 001009106.1_39724001_1 - 8.1e-49 165.5 0.1 1.1e-48 165.0 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.12 001009106.1_39724001_1 - 9e-17 60.7 0.0 1.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DUF258 PF03193.14 001009106.1_39724001_1 - 2.9e-05 23.9 0.1 0.044 13.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001009106.1_39724001_1 - 0.00024 20.6 0.4 0.047 13.1 0.1 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_23 PF13476.4 001009106.1_39724001_1 - 0.019 15.3 1.3 0.025 15.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.7 001009106.1_39724001_1 - 0.02 13.6 0.0 0.04 12.6 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class ArgK PF03308.14 001009106.1_39724001_1 - 0.025 13.4 0.2 6.5 5.5 0.0 2.8 3 0 0 3 3 3 0 ArgK protein AAA_16 PF13191.4 001009106.1_39724001_1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.21 001009106.1_39724001_1 - 0.059 13.3 0.1 0.25 11.3 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.15 001009106.1_39724001_1 - 0.06 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.25 001009106.1_39724001_1 - 0.065 13.6 0.2 0.18 12.2 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Zeta_toxin PF06414.10 001009106.1_39724001_1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.4 001009106.1_39724001_1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pur_DNA_glyco PF02245.14 001203259.1_29623001_3 - 3.4e-60 202.3 0.0 4.3e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Tubulin PF00091.23 001246650.1_39724001_2 - 2e-67 227.1 0.0 2.7e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001246650.1_39724001_2 - 2.8e-51 172.9 0.0 4.4e-51 172.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.4 001246650.1_39724001_2 - 0.0019 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain zf-CCHC_3 PF13917.4 001190872.1_29622001_1 - 2.2e-17 62.6 5.3 3.8e-17 61.8 5.3 1.4 1 0 0 1 1 1 1 Zinc knuckle CLIP1_ZNF PF16641.3 001190872.1_29622001_1 - 0.12 12.1 1.8 0.23 11.2 1.8 1.5 1 0 0 1 1 1 0 CLIP1 zinc knuckle BUD22 PF09073.8 001190872.1_29622001_1 - 0.42 9.8 33.5 0.53 9.4 33.5 1.1 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.7 001190872.1_29622001_1 - 1.3 7.6 29.7 1.7 7.3 29.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.7 001190872.1_29622001_1 - 5.2 5.4 31.2 7 4.9 31.2 1.1 1 0 0 1 1 1 0 Transmembrane protein FAM75 PF14650.4 001190872.1_29622001_2 - 0.8 9.1 8.6 1.1 8.6 8.6 1.1 1 0 0 1 1 1 0 FAM75 family RRM_1 PF00076.20 001246382.1_39726001_2 - 1.7e-28 98.1 0.0 6.2e-16 57.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.4 001246382.1_39726001_2 - 2.1e-08 33.7 0.0 0.0036 16.8 0.1 2.7 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.13 001246382.1_39726001_2 - 0.0051 16.6 0.1 0.018 14.9 0.1 1.8 2 0 0 2 2 2 1 DbpA RNA binding domain RRM_occluded PF16842.3 001246382.1_39726001_2 - 0.0073 16.0 0.1 0.21 11.4 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.6 001246382.1_39726001_2 - 0.13 12.2 0.1 0.54 10.2 0.1 1.9 2 0 0 2 2 2 0 Limkain b1 C2-set_2 PF08205.10 001043386.1_29623001_1 - 4e-22 78.0 3.7 1.3e-21 76.4 0.2 3.1 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.4 001043386.1_29623001_1 - 2.4e-15 56.8 3.0 0.00013 22.4 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.23 001043386.1_29623001_1 - 1.1e-13 51.1 0.2 0.0012 18.9 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001043386.1_29623001_1 - 4.1e-12 46.1 0.0 1.9e-10 40.7 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.4 001043386.1_29623001_1 - 2.4e-07 30.9 0.7 0.056 13.7 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.14 001043386.1_29623001_1 - 4.1e-07 29.8 0.0 0.21 11.5 0.0 3.8 3 2 0 3 3 3 2 Immunoglobulin I-set domain C1-set PF07654.13 001043386.1_29623001_1 - 0.0076 16.6 0.2 1.1 9.7 0.0 3.3 2 1 1 3 3 3 1 Immunoglobulin C1-set domain WD40 PF00400.30 001246481.1_39725001_3 - 2.4e-07 31.2 20.1 3.8e-05 24.2 0.1 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001246481.1_39725001_3 - 0.00016 21.8 1.2 0.015 15.4 0.0 3.4 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.6 001246481.1_39725001_3 - 0.0056 14.9 0.2 0.0077 14.5 0.2 1.1 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz TFIIIC_delta PF12657.5 001246481.1_39725001_3 - 0.1 12.4 0.1 0.32 10.8 0.1 1.7 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term LT-IIB PF06453.9 001246481.1_39725001_3 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) PET PF06297.12 001113750.1_45723001_3 - 2.7e-31 107.6 1.1 5.6e-31 106.6 1.1 1.6 1 0 0 1 1 1 1 PET Domain LIM PF00412.20 001113750.1_45723001_3 - 1.1e-29 102.3 56.7 5.7e-15 55.2 6.4 4.3 4 1 0 4 4 4 3 LIM domain DUF2685 PF10886.6 001113750.1_45723001_3 - 0.036 14.1 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) Metallophos PF00149.26 001082692.1_37925001_2 - 2.4e-38 132.6 0.0 3.9e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sds3 PF08598.9 001166189.1_39522001_1 - 6.6e-19 68.7 2.0 6.6e-19 68.7 2.0 2.0 2 1 1 3 3 3 1 Sds3-like Dynactin_p62 PF05502.11 001166189.1_39522001_1 - 0.42 9.2 5.3 0.24 10.0 3.5 1.4 1 1 0 1 1 1 0 Dynactin p62 family PIP5K PF01504.16 001166189.1_39522001_1 - 0.45 9.6 4.0 1.1 8.2 4.0 1.7 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Vfa1 PF08432.8 001166189.1_39522001_1 - 0.68 10.1 8.4 1.6 8.9 7.0 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Tup_N PF08581.8 001166189.1_39522001_1 - 0.9 9.8 11.9 0.18 12.0 3.8 2.8 3 0 0 3 3 3 0 Tup N-terminal CDC45 PF02724.12 001166189.1_39522001_1 - 0.99 7.5 8.8 1.6 6.8 8.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.7 001166189.1_39522001_1 - 3.8 6.1 8.8 3.3 6.3 0.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ig_2 PF13895.4 001042624.1_39722001_1 - 9.6e-13 48.2 0.0 3.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.23 001042624.1_39722001_1 - 1.7e-09 37.6 0.0 0.0002 21.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.4 001042624.1_39722001_1 - 2.7e-08 34.1 0.0 0.00068 20.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Adeno_E1B_19K PF01691.14 001042624.1_39722001_1 - 0.07 12.5 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen V-set PF07686.15 001042624.1_39722001_1 - 0.12 12.4 0.3 6.4 6.8 0.0 3.1 2 2 2 4 4 4 0 Immunoglobulin V-set domain Forkhead PF00250.16 001009014.1_39725001_2 - 1.4e-34 118.1 0.0 2.2e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain DEAD PF00270.27 001246853.1_37625001_1 - 4.6e-48 163.2 0.0 1e-47 162.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001246853.1_37625001_1 - 1e-31 109.5 0.3 6.1e-31 106.9 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.13 001246853.1_37625001_1 - 0.003 17.4 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SCF PF02404.13 001082223.1_37922001_1 - 3.7e-153 508.4 1.8 4.2e-153 508.3 1.8 1.0 1 0 0 1 1 1 1 Stem cell factor DUF4448 PF14610.4 001082223.1_37922001_1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ank_2 PF12796.5 001246456.1_39724001_3 - 5.2e-26 90.9 3.3 1.4e-14 54.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.28 001246456.1_39724001_3 - 3.1e-19 68.3 1.3 5.1e-07 29.7 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.4 001246456.1_39724001_3 - 5.2e-19 67.9 4.0 1.2e-07 31.7 0.1 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.4 001246456.1_39724001_3 - 5.5e-19 66.1 0.4 2.8e-05 24.0 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.4 001246456.1_39724001_3 - 3.5e-17 62.4 0.9 7.4e-09 35.8 0.4 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) GST_C_3 PF14497.4 001106464.1_45723001_1 - 1.8e-17 63.2 0.2 3e-17 62.5 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.18 001106464.1_45723001_1 - 4.7e-17 62.0 0.0 9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.23 001106464.1_45723001_1 - 1e-14 54.4 0.1 1.6e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.2 001106464.1_45723001_1 - 0.00064 19.3 0.4 0.0019 17.8 0.4 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.4 001106464.1_45723001_1 - 0.0021 18.3 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.4 001106464.1_45723001_1 - 0.14 11.9 0.0 1.8 8.4 0.0 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ig PF00047.23 001104609.1_39723001_1 - 5.3e-34 116.1 0.0 3.3e-11 43.1 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.4 001104609.1_39723001_1 - 2.2e-15 56.6 0.0 1.3e-06 28.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.4 001104609.1_39723001_1 - 7.4e-15 55.2 0.0 8.3e-05 23.0 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.15 001104609.1_39723001_1 - 4.2e-06 26.7 0.2 0.51 10.4 0.0 4.7 3 3 1 4 4 4 2 Immunoglobulin V-set domain SIT PF15330.4 001104609.1_39723001_1 - 0.005 17.1 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT Ig_4 PF16680.3 001104609.1_39723001_1 - 0.057 13.7 0.3 7.7 6.8 0.0 3.9 3 3 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Ion_trans PF00520.29 001198982.1_37923001_1 - 3.3e-51 173.8 12.5 4.5e-51 173.3 12.5 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.20 001198982.1_37923001_1 - 7.1e-29 99.9 0.3 1.7e-28 98.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.14 001198982.1_37923001_1 - 5.2e-14 51.8 5.3 5.2e-14 51.8 5.3 2.8 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.10 001198982.1_37923001_1 - 0.0022 16.6 1.8 0.0025 16.4 0.8 1.6 1 1 0 1 1 1 1 Polycystin cation channel Sigma_reg_N PF13800.4 001198982.1_37923001_1 - 0.056 13.6 4.4 2.4 8.3 0.1 3.8 4 0 0 4 4 4 0 Sigma factor regulator N-terminal DUF423 PF04241.13 001198982.1_37923001_1 - 3.5 7.7 4.7 1.1 9.4 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DctQ PF04290.10 001198982.1_37923001_1 - 3.5 7.4 8.2 2 8.2 0.6 3.0 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component ANF_receptor PF01094.26 001164700.1_39726001_1 - 8.3e-82 275.0 0.0 1.2e-81 274.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.24 001164700.1_39726001_1 - 4.1e-55 185.6 0.2 6.4e-55 185.0 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.7 001164700.1_39726001_1 - 2.6e-46 156.4 0.1 1.3e-45 154.1 0.0 2.3 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.18 001164700.1_39726001_1 - 6.6e-18 64.8 0.0 1.2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.4 001164700.1_39726001_1 - 3.6e-09 36.7 0.0 7.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein BAR_3 PF16746.3 001135961.1_49824001_1 - 2.9e-68 230.0 12.6 6e-68 228.9 12.6 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.27 001135961.1_49824001_1 - 7.6e-10 39.1 0.0 1.1e-07 32.1 0.0 3.0 3 0 0 3 3 3 1 PH domain PID PF00640.21 001135961.1_49824001_1 - 2.1e-07 30.9 0.5 7.2e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.11 001135961.1_49824001_1 - 1.2e-06 28.6 0.0 3.5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PH_9 PF15410.4 001135961.1_49824001_1 - 0.0028 17.9 0.0 0.012 15.8 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.8 001135961.1_49824001_1 - 0.02 15.1 0.1 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Pox_RNA_pol_35 PF03396.13 001135961.1_49824001_1 - 0.046 12.8 0.4 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase, 35 kD subunit DUF3263 PF11662.6 001135961.1_49824001_1 - 0.079 12.7 0.1 0.32 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) IMUP PF15761.3 001008979.1_39725001_1 - 2 9.0 7.3 4.2 8.0 7.3 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Ig_2 PF13895.4 001008979.1_39725001_3 - 2.5e-32 110.9 0.6 1.8e-13 50.5 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.4 001008979.1_39725001_3 - 3.6e-29 101.1 1.7 2.7e-06 27.8 0.3 4.5 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.23 001008979.1_39725001_3 - 1.2e-17 63.8 0.1 0.00043 20.3 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.15 001008979.1_39725001_3 - 2.7e-06 27.4 2.2 8.3 6.5 0.0 6.5 5 2 0 6 6 6 1 Immunoglobulin V-set domain Izumo-Ig PF16706.3 001008979.1_39725001_3 - 0.018 14.9 0.0 7.2 6.6 0.0 3.3 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF3116 PF11313.6 001008979.1_39725001_3 - 0.019 14.7 0.0 7.5 6.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3116) EphA2_TM PF14575.4 001008979.1_39725001_3 - 0.088 13.5 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain I-set PF07679.14 001008979.1_39725001_3 - 0.088 12.7 0.0 24 4.9 0.0 3.8 3 1 0 3 3 3 0 Immunoglobulin I-set domain HemY_N PF07219.11 001008979.1_39725001_3 - 0.17 12.0 1.5 0.31 11.1 1.5 1.3 1 0 0 1 1 1 0 HemY protein N-terminus SIT PF15330.4 001008979.1_39725001_3 - 0.72 10.1 6.5 10 6.4 2.0 2.7 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Filament PF00038.19 001098570.1_39725001_2 - 3.1e-98 329.1 27.4 3.7e-98 328.8 27.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.3 001098570.1_39725001_2 - 8.3e-14 51.9 16.1 1.1e-10 41.7 1.3 3.1 2 1 1 3 3 3 2 Keratin type II head BAT PF15915.3 001098570.1_39725001_2 - 0.00022 21.0 0.9 0.00043 20.1 0.9 1.4 1 0 0 1 1 1 1 GAF and HTH_10 associated domain TPR_MLP1_2 PF07926.10 001098570.1_39725001_2 - 0.00023 21.1 25.8 0.00061 19.7 0.7 3.5 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein DUF4924 PF16271.3 001098570.1_39725001_2 - 0.027 14.4 0.7 0.051 13.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) Spc7 PF08317.9 001098570.1_39725001_2 - 0.077 11.7 23.4 0.13 11.0 9.0 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein BRE1 PF08647.9 001098570.1_39725001_2 - 0.5 10.3 9.5 0.4 10.6 1.7 3.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF1192 PF06698.9 001098570.1_39725001_2 - 0.6 10.1 6.9 1.1 9.3 4.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CALCOCO1 PF07888.9 001098570.1_39725001_2 - 2 6.7 26.2 1.4 7.3 19.7 2.3 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.10 001098570.1_39725001_2 - 7.8 6.4 6.4 5.8 6.8 0.7 2.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Ion_trans PF00520.29 001145753.1_49826001_1 - 6.7e-33 113.8 14.1 9.4e-33 113.3 14.1 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.9 001145753.1_49826001_1 - 1.1e-25 89.4 1.9 2.5e-25 88.3 1.9 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.10 001145753.1_49826001_1 - 4.1e-12 45.4 12.0 9.8e-12 44.1 12.0 1.6 1 1 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.5 001145753.1_49826001_1 - 6.8e-10 39.3 0.2 2.4e-06 27.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.4 001145753.1_49826001_1 - 2.3e-05 24.5 0.3 1.1 9.6 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.4 001145753.1_49826001_1 - 0.00097 19.5 0.3 0.055 13.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.4 001145753.1_49826001_1 - 0.0013 18.9 2.0 25 5.7 0.0 4.9 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.28 001145753.1_49826001_1 - 0.021 15.1 2.5 18 5.9 0.0 3.5 2 1 1 3 3 3 0 Ankyrin repeat ING PF12998.5 001145753.1_49826001_1 - 0.081 13.4 5.2 1 9.8 1.8 3.0 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Phage_holin_3_6 PF07332.9 001145753.1_49826001_1 - 1.9 8.4 4.0 3.1 7.7 0.1 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Lig_chan PF00060.24 001145753.1_49826001_1 - 5.7 6.6 6.2 16 5.2 0.2 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel Beta_helix PF13229.4 001246493.1_39725001_2 - 8.8e-13 48.3 3.0 4.2e-12 46.1 3.0 1.9 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.11 001246493.1_39725001_2 - 2.4e-08 33.4 1.8 3.8e-08 32.8 1.8 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) SYS1 PF09801.7 001246408.1_39724001_1 - 4.4e-52 175.9 3.9 7.8e-52 175.2 3.9 1.4 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Peptidase_C97 PF05903.12 001243397.1_49822001_1 - 1.2e-43 148.4 0.0 1.5e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain SOCS PF12610.6 001193820.1_29626001_2 - 1.3e-21 76.6 3.1 2.8e-21 75.5 3.1 1.5 1 0 0 1 1 1 1 Suppressor of cytokine signalling SOCS_box PF07525.14 001193820.1_29626001_2 - 2.5e-10 40.4 0.1 4.6e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 SOCS box SH2 PF00017.22 001193820.1_29626001_2 - 1.7e-07 31.0 0.0 3.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PQ-loop PF04193.12 001266148.1_29623001_2 - 1.7e-20 72.4 3.1 2.3e-13 49.6 0.5 2.8 3 0 0 3 3 3 2 PQ loop repeat Serpin PF00079.18 001195350.1_29624001_2 - 5.9e-115 384.4 1.5 6.9e-115 384.2 1.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Aldo_ket_red PF00248.19 001283803.1_29524001_1 - 1.5e-05 24.2 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1_like PF12832.5 001328311.1_39725001_1 - 6.4e-42 143.6 2.2 8.6e-42 143.2 2.2 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.14 001328311.1_39725001_1 - 3.7e-11 42.4 27.5 1.9e-07 30.2 14.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Wzy_C PF04932.13 001328311.1_39725001_1 - 1.3 8.5 10.5 16 5.0 0.0 3.6 3 1 0 3 3 3 0 O-Antigen ligase RINGv PF12906.5 001284961.1_29525001_2 - 1.4e-15 57.0 7.6 3e-15 55.9 7.6 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.6 001284961.1_29525001_2 - 0.0009 19.2 3.3 0.0009 19.2 3.3 2.0 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.4 001284961.1_29525001_2 - 0.0064 16.6 4.5 0.014 15.5 4.5 1.7 1 0 0 1 1 1 1 Ring finger domain SP_C-Propep PF08999.8 001283171.1_29522001_2 - 0.036 13.7 1.3 0.056 13.1 0.4 1.8 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide TMEM154 PF15102.4 001283171.1_29522001_2 - 0.045 13.5 0.2 0.085 12.6 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family m04gp34like PF12216.6 001283171.1_29522001_2 - 0.063 12.7 0.1 0.095 12.1 0.1 1.2 1 0 0 1 1 1 0 Immune evasion protein SARAF PF06682.10 001283171.1_29522001_2 - 0.079 12.5 0.3 0.83 9.1 0.0 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Galactosyl_T PF01762.19 001261632.1_29624001_2 - 4.6e-40 137.4 0.0 6.1e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.14 001261632.1_29624001_2 - 0.011 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Fringe-like DUF604 PF04646.10 001261632.1_29624001_2 - 0.02 14.1 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 p450 PF00067.20 001319508.1_29525001_2 - 5.3e-54 183.6 0.0 6.9e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CCHC_6 PF15288.4 001319508.1_29525001_3 - 0.064 13.0 1.3 0.16 11.7 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle 7tm_1 PF00001.19 001284883.1_29523001_1 - 1.6e-48 165.1 10.0 2.3e-48 164.6 10.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.7 001284883.1_29523001_1 - 1.2e-05 24.7 1.9 1.7e-05 24.2 1.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.7 001284883.1_29523001_1 - 0.00033 19.9 6.2 0.0082 15.3 6.2 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.7 001284883.1_29523001_1 - 0.00055 19.2 3.6 0.00055 19.2 3.6 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Exo_endo_phos PF03372.21 001194013.1_29625001_1 - 7.5e-07 29.3 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M24 PF00557.22 001266962.1_29625001_3 - 1.1e-49 168.9 0.0 1.5e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.3 001266962.1_29625001_3 - 1.3e-46 158.5 0.0 2e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.3 001266962.1_29625001_3 - 2.3e-23 81.9 0.1 6.6e-23 80.4 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.16 001266962.1_29625001_3 - 1.6e-13 51.3 0.0 1.8e-11 44.6 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain CALCOCO1 PF07888.9 001266932.1_29627001_2 - 9.7e-89 298.4 29.4 9.7e-89 298.4 29.4 2.8 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C2H2_4 PF13894.4 001266932.1_29627001_2 - 0.041 14.6 5.9 1.1 10.1 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.10 001266932.1_29627001_2 - 0.4 10.9 4.1 1.5 9.1 4.1 2.0 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding UBZ_FAAP20 PF15750.3 001266932.1_29627001_2 - 0.89 9.4 6.0 1.7 8.5 1.1 2.7 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Ig_4 PF16680.3 001266925.2_29623001_1 - 5.6e-29 100.2 1.3 1e-28 99.4 1.3 1.4 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.3 001266925.2_29623001_1 - 1.4e-09 38.1 1.3 2.5e-09 37.3 1.3 1.3 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ITAM PF02189.13 001266925.2_29623001_1 - 4.7e-08 32.9 3.4 1.2e-07 31.6 3.4 1.7 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif Ig_3 PF13927.4 001266925.2_29623001_1 - 0.0044 17.5 0.2 0.0091 16.5 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.23 001266925.2_29623001_1 - 0.012 15.7 0.5 0.025 14.6 0.5 1.5 1 1 0 1 1 1 0 Immunoglobulin domain zf-C4 PF00105.16 001280163.1_39724001_1 - 1.9e-28 98.6 18.1 3.4e-28 97.8 18.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001280163.1_39724001_1 - 3.8e-19 69.0 4.1 7.1e-19 68.1 4.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ELO PF01151.16 001283586.1_29523001_3 - 2.4e-63 213.9 23.1 3.1e-63 213.5 23.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Tsc35 PF15079.4 001287660.1_29523001_1 - 1.7e-101 337.9 15.8 8.5e-91 303.0 9.8 2.7 3 0 0 3 3 3 2 Testis-specific protein 35 DUF848 PF05852.9 001287660.1_29523001_1 - 0.048 13.6 5.0 0.12 12.3 5.0 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) IncA PF04156.12 001287660.1_29523001_1 - 0.64 9.7 5.4 1.6 8.4 5.2 1.7 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.10 001287660.1_29523001_1 - 1.4 8.8 7.4 0.15 11.9 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COMP PF11598.6 001287660.1_29523001_1 - 6.5 7.2 8.7 2 8.8 2.8 2.4 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein DUF778 PF05608.10 001283974.1_29524001_2 - 6.9e-43 147.0 4.6 1.3e-24 87.5 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Arf PF00025.19 001283838.1_29524001_1 - 3.4e-59 199.1 0.0 4.6e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.8 001283838.1_29524001_1 - 1.2e-09 37.7 0.0 1.6e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.11 001283838.1_29524001_1 - 1.4e-07 31.6 0.0 2.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.18 001283838.1_29524001_1 - 1.5e-07 30.8 0.1 8.8e-06 25.0 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.20 001283838.1_29524001_1 - 1.7e-06 27.6 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.21 001283838.1_29524001_1 - 5.2e-05 23.2 0.0 7.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001283838.1_29524001_1 - 0.0033 16.8 0.1 0.017 14.5 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.10 001283838.1_29524001_1 - 0.039 13.2 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Peptidase_M24 PF00557.22 001285100.1_29525001_3 - 1.5e-55 188.0 0.0 2e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.14 001285100.1_29525001_3 - 1.2e-36 125.0 0.0 2e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3699 PF12480.6 001145401.1_45727001_1 - 1.8e-20 72.7 0.3 4.1e-20 71.6 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3699) Motilin_assoc PF04643.10 001304895.1_01321001_3 - 1.1e-34 117.9 0.2 1.5e-34 117.5 0.2 1.2 1 0 0 1 1 1 1 Motilin/ghrelin-associated peptide Motilin_ghrelin PF04644.10 001304895.1_01321001_3 - 9.7e-11 41.2 4.1 1.4e-10 40.7 4.1 1.2 1 0 0 1 1 1 1 Motilin/ghrelin RNase_P_Rpp14 PF01900.17 001266712.1_29624001_1 - 3.4e-08 33.5 0.0 5.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family MaoC_dehydratas PF01575.17 001266712.1_29624001_2 - 4e-17 61.8 0.0 5.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.4 001266712.1_29624001_2 - 0.0089 16.0 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase CH PF00307.29 001283712.1_29523001_1 - 6.2e-18 64.9 0.0 8.9e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.16 001283712.1_29523001_1 - 5.4e-13 48.2 7.0 5.5e-13 48.2 4.8 2.0 2 0 0 2 2 2 1 Calponin family repeat Ras PF00071.20 001242371.2_39725001_1 - 1.4e-65 219.7 0.5 1.8e-65 219.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001242371.2_39725001_1 - 9.8e-33 112.8 0.1 1.5e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001242371.2_39725001_1 - 1.7e-15 56.8 0.3 2.5e-15 56.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.10 001242371.2_39725001_1 - 0.0001 21.6 0.1 0.00013 21.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.8 001242371.2_39725001_1 - 0.0048 16.2 0.1 0.0073 15.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.21 001242371.2_39725001_1 - 0.031 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001242371.2_39725001_1 - 0.045 13.1 0.1 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF258 PF03193.14 001242371.2_39725001_1 - 0.089 12.6 0.2 14 5.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF3963 PF13124.4 001242371.2_39725001_1 - 0.13 12.2 0.8 0.24 11.3 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) GTP_EFTU PF00009.25 001261690.1_29626001_1 - 1.7e-63 213.5 0.0 2.5e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.16 001261690.1_29626001_1 - 1.1e-34 118.7 0.0 2.8e-34 117.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.4 001261690.1_29626001_1 - 5.1e-29 100.1 0.0 9.6e-29 99.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.22 001261690.1_29626001_1 - 2.9e-23 81.6 0.0 8.9e-23 80.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.23 001261690.1_29626001_1 - 2.2e-18 66.3 0.0 5.6e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.3 001261690.1_29626001_1 - 1.5e-06 28.0 0.0 8.2e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.21 001261690.1_29626001_1 - 0.0051 16.7 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.14 001261690.1_29626001_1 - 0.035 13.3 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AvrPtoB_bdg PF16847.3 001261690.1_29626001_1 - 0.038 14.4 0.0 0.33 11.3 0.0 2.4 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain DnaJ PF00226.29 001285080.1_29523001_2 - 1.5e-26 92.1 3.1 2.4e-26 91.5 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4655 PF15548.4 001317011.1_39727001_2 - 1.1e-265 882.7 41.8 1.7e-265 882.0 41.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4655) Septin PF00735.16 001317011.1_39727001_2 - 2.8e-127 423.6 0.0 3.9e-127 423.2 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.21 001317011.1_39727001_2 - 2.4e-06 27.5 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.14 001317011.1_39727001_2 - 7.5e-06 25.8 0.0 0.00065 19.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.25 001317011.1_39727001_2 - 0.0032 16.9 0.1 0.51 9.7 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.14 001317011.1_39727001_2 - 0.016 14.4 0.1 0.036 13.3 0.0 1.6 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.21 001317011.1_39727001_2 - 0.033 14.1 0.2 6.1 6.7 0.0 2.7 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.4 001317011.1_39727001_2 - 0.07 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Hexapep PF00132.22 001317011.1_39727001_2 - 0.12 12.0 0.4 3.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) AAA_29 PF13555.4 001317011.1_39727001_2 - 0.14 11.8 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNase_T PF00929.22 001287705.1_29523001_3 - 6.1e-33 114.6 0.0 7.7e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease MITF_TFEB_C_3_N PF15951.3 001266857.1_29624001_2 - 2e-49 168.0 21.2 2e-49 168.0 21.2 2.5 2 1 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus DUF3371 PF11851.6 001266857.1_29624001_2 - 1.9e-37 129.0 0.9 1.9e-37 129.0 0.9 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3371) HLH PF00010.24 001266857.1_29624001_2 - 5.9e-17 61.2 0.5 1.7e-16 59.8 0.5 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF726 PF05277.10 001266857.1_29624001_2 - 0.08 11.7 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Ribophorin_I PF04597.12 001266857.1_29624001_2 - 0.79 8.7 5.5 1.2 8.1 5.5 1.2 1 0 0 1 1 1 0 Ribophorin I TFIIA PF03153.11 001266857.1_29624001_2 - 4.7 7.0 17.6 8.8 6.1 17.6 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ubiquitin PF00240.21 001283983.1_29522001_1 - 1.2e-88 290.7 8.2 5.4e-34 115.6 0.3 3.1 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.6 001283983.1_29522001_1 - 1.1e-40 137.1 7.4 4.4e-16 58.3 0.4 3.1 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.4 001283983.1_29522001_1 - 2.9e-18 66.0 1.9 7.9e-05 22.9 0.1 4.0 3 2 0 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.4 001283983.1_29522001_1 - 4.2e-07 29.9 0.5 0.076 13.0 0.0 3.3 3 2 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.7 001283983.1_29522001_1 - 1.3e-05 25.5 0.1 0.2 12.1 0.1 2.9 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain RBD PF02196.13 001283983.1_29522001_1 - 0.0027 17.6 0.0 19 5.3 0.0 3.3 3 0 0 3 3 3 0 Raf-like Ras-binding domain Telomere_Sde2 PF13019.4 001283983.1_29522001_1 - 0.0028 17.4 0.0 2.1 8.0 0.0 2.4 2 1 1 3 3 3 2 Telomere stability and silencing Methyltrans_RNA PF04452.12 001283983.1_29522001_1 - 0.0045 16.2 0.1 1.9 7.7 0.0 2.2 2 0 0 2 2 2 2 RNA methyltransferase DUF2870 PF11069.6 001283983.1_29522001_1 - 0.011 15.9 0.0 10 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) DUF3861 PF12977.5 001283983.1_29522001_1 - 0.011 15.7 0.2 41 4.3 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) FERM_f0 PF16511.3 001283983.1_29522001_1 - 0.017 15.3 4.2 29 4.9 0.2 4.6 3 2 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM FlgD_ig PF13860.4 001283983.1_29522001_1 - 0.023 14.4 2.3 20 4.9 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain CorA PF01544.16 001283983.1_29522001_1 - 0.058 12.6 0.2 21 4.2 0.0 2.9 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein ProRS-C_2 PF09181.8 001283983.1_29522001_1 - 0.17 11.9 0.9 1e+02 3.0 0.0 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal ubiquitin PF00240.21 001283983.1_29522001_2 - 2.9e-05 23.6 0.0 4.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1151 PF06625.9 001257546.1_29623001_2 - 2.1e-39 133.9 17.3 2.9e-39 133.4 17.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) KIAA1328 PF15369.4 001257546.1_29623001_2 - 0.12 12.1 8.8 0.18 11.5 8.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 DUF3552 PF12072.6 001257546.1_29623001_2 - 1.3 8.3 8.2 1.9 7.7 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Tubulin PF00091.23 001280021.1_39724001_3 - 3.3e-69 232.9 0.0 5.2e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.15 001280021.1_39724001_3 - 2e-47 160.4 0.1 3.7e-47 159.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.7 001280021.1_39724001_3 - 0.00023 21.3 0.0 0.00061 19.9 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.4 001280021.1_39724001_3 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.4 001280021.1_39724001_3 - 0.059 12.4 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Pyridoxal_deC PF00282.17 001319399.1_29525001_2 - 2.1e-172 572.9 0.0 2.5e-172 572.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.19 001319399.1_29525001_2 - 2.3e-06 27.0 0.0 4.8e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.19 001319399.1_29525001_2 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Sdh5 PF03937.14 001251854.1_39722001_3 - 3.3e-24 84.5 0.4 5.1e-24 83.9 0.4 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Peroxidase_2 PF01328.15 001251854.1_39722001_3 - 0.075 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Peroxidase, family 2 TFIIE_alpha PF02002.15 001251854.1_39722001_3 - 0.1 12.3 0.2 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Ig_3 PF13927.4 001265772.1_29629001_1 - 4.7e-74 244.9 0.2 3.3e-13 49.9 0.0 6.7 7 0 0 7 7 6 6 Immunoglobulin domain I-set PF07679.14 001265772.1_29629001_1 - 4e-65 215.8 0.0 2.3e-14 53.1 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.23 001265772.1_29629001_1 - 1.4e-51 172.5 0.0 2.8e-09 36.9 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.4 001265772.1_29629001_1 - 4.7e-48 161.3 0.0 5.4e-08 32.9 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.19 001265772.1_29629001_1 - 3.4e-45 152.2 7.6 1.1e-17 64.0 0.1 4.6 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.15 001265772.1_29629001_1 - 1.4e-18 66.9 3.3 0.03 14.4 0.0 8.6 6 4 1 7 7 7 4 Immunoglobulin V-set domain Ig_5 PF16681.3 001265772.1_29629001_1 - 4.6e-09 36.4 0.0 0.057 13.7 0.0 5.2 6 0 0 6 6 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.3 001265772.1_29629001_1 - 5.5e-06 26.7 0.3 0.0034 17.8 0.3 2.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.10 001265772.1_29629001_1 - 4.2e-05 23.4 0.2 0.24 11.4 0.0 3.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.3 001265772.1_29629001_1 - 4.9e-05 23.2 0.1 0.17 11.8 0.0 4.6 6 0 0 6 6 5 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.3 001265772.1_29629001_1 - 9.3e-05 22.6 0.0 3.1 8.1 0.0 4.4 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.13 001265772.1_29629001_1 - 0.0016 18.4 0.0 1.3 9.1 0.0 3.8 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Sp38 PF07354.10 001265772.1_29629001_1 - 0.033 12.9 0.0 0.18 10.5 0.0 2.1 3 0 0 3 3 3 0 Zona-pellucida-binding protein (Sp38) Adeno_E3_CR1 PF02440.13 001265772.1_29629001_1 - 0.082 12.6 0.0 1.8 8.3 0.0 3.1 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 Interfer-bind PF09294.8 001265772.1_29629001_1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Patatin PF01734.20 001193844.1_29622001_1 - 2.6e-17 63.5 0.1 3.6e-16 59.8 0.1 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase CKS PF01111.17 001265747.1_29622001_1 - 2e-37 127.1 1.2 2e-37 127.1 1.2 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit EF-hand_1 PF00036.30 001283207.1_29524001_1 - 1.1e-15 55.8 23.3 0.002 17.4 0.4 7.3 7 0 0 7 7 7 6 EF hand EF-hand_7 PF13499.4 001283207.1_29524001_1 - 1.4e-15 57.3 23.0 0.00016 22.0 3.1 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.4 001283207.1_29524001_1 - 1.1e-13 49.8 18.2 0.0032 17.1 0.1 7.3 7 0 0 7 7 7 6 EF-hand domain EF-hand_5 PF13202.4 001283207.1_29524001_1 - 1.3e-10 40.2 32.5 0.0055 16.0 0.6 7.0 8 0 0 8 8 8 5 EF hand EF-hand_8 PF13833.4 001283207.1_29524001_1 - 1.1e-06 28.2 11.1 0.0017 17.9 0.0 4.8 5 0 0 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001283207.1_29524001_1 - 0.48 10.6 14.3 4.9 7.4 0.2 3.9 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region MFS_1 PF07690.14 001194790.1_29624001_3 - 1e-48 165.9 45.2 1.1e-46 159.3 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.22 001194790.1_29624001_3 - 6.9e-05 21.7 23.3 0.039 12.7 7.3 4.0 4 0 0 4 4 4 4 Sugar (and other) transporter EF-hand_7 PF13499.4 001283164.1_29524001_1 - 3.7e-27 94.5 4.0 3.5e-17 62.5 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.30 001283164.1_29524001_1 - 3.9e-25 85.4 4.8 1.2e-06 27.5 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.4 001283164.1_29524001_1 - 8.7e-22 75.0 2.9 2.3e-06 26.9 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.4 001283164.1_29524001_1 - 8.3e-21 72.4 2.6 1.1e-06 27.8 0.3 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.4 001283164.1_29524001_1 - 8e-19 67.0 1.4 1.9e-07 30.6 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.7 001283164.1_29524001_1 - 1.7e-05 25.0 0.3 0.011 15.9 0.1 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.5 001283164.1_29524001_1 - 0.00022 21.0 0.6 0.77 9.6 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.4 001283164.1_29524001_1 - 0.062 13.0 0.1 16 5.3 0.1 2.5 2 0 0 2 2 2 0 EF hand FANCF PF11107.6 001193823.1_29622001_2 - 0.031 13.4 0.4 0.044 12.9 0.4 1.3 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) RPE65 PF03055.13 001308571.1_39524001_3 - 8.1e-109 364.4 0.0 9.3e-109 364.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Tropomyosin PF00261.18 001284076.1_29523001_1 - 3.4e-93 311.2 59.2 4.1e-93 311.0 59.2 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.5 001284076.1_29523001_1 - 2.2e-23 82.8 58.1 7.7e-20 71.3 25.5 3.2 1 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.10 001284076.1_29523001_1 - 8.1e-05 22.5 29.3 0.00013 21.9 8.3 3.4 1 1 3 4 4 4 2 Laminin Domain II DUF3450 PF11932.6 001284076.1_29523001_1 - 0.0013 18.0 9.0 0.0013 18.0 9.0 3.0 1 1 3 4 4 4 1 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.6 001284076.1_29523001_1 - 0.0081 16.0 15.1 0.0081 16.0 15.1 5.4 2 1 2 5 5 4 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.7 001284076.1_29523001_1 - 0.018 15.0 51.6 0.048 13.6 31.7 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC144C PF14915.4 001284076.1_29523001_1 - 0.04 12.9 40.9 0.042 12.9 3.7 3.0 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region TSC22 PF01166.16 001284076.1_29523001_1 - 0.044 14.0 4.8 0.11 12.7 0.8 3.3 2 0 0 2 2 2 0 TSC-22/dip/bun family CALCOCO1 PF07888.9 001284076.1_29523001_1 - 0.048 12.1 42.3 0.068 11.6 42.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.10 001284076.1_29523001_1 - 0.12 11.6 2.8 0.23 10.7 0.7 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein MscS_porin PF12795.5 001284076.1_29523001_1 - 0.13 11.6 40.6 3.3 7.1 23.7 2.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain FPP PF05911.9 001284076.1_29523001_1 - 0.16 10.1 42.2 0.4 8.7 33.8 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil HrpB7 PF09486.8 001284076.1_29523001_1 - 0.19 11.9 46.1 0.16 12.2 5.2 3.3 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.10 001284076.1_29523001_1 - 0.27 11.1 23.2 0.14 12.0 2.5 3.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) XhlA PF10779.7 001284076.1_29523001_1 - 0.4 10.8 40.0 0.069 13.2 1.5 6.0 4 2 3 7 7 6 0 Haemolysin XhlA Uds1 PF15456.4 001284076.1_29523001_1 - 0.41 10.7 38.7 4 7.5 0.9 4.9 1 1 2 4 4 4 0 Up-regulated During Septation Alanine_zipper PF11839.6 001284076.1_29523001_1 - 0.42 10.8 35.5 0.97 9.6 3.8 4.4 1 1 3 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein Fib_alpha PF08702.8 001284076.1_29523001_1 - 0.55 10.3 22.6 0.5 10.4 5.9 2.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF724 PF05266.12 001284076.1_29523001_1 - 0.68 9.6 41.2 0.47 10.1 6.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.7 001284076.1_29523001_1 - 0.89 8.8 44.5 1.1 8.5 16.4 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.7 001284076.1_29523001_1 - 1.1 9.3 53.5 15 5.7 24.4 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF745 PF05335.11 001284076.1_29523001_1 - 1.8 8.1 39.9 1.4 8.5 8.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) EzrA PF06160.10 001284076.1_29523001_1 - 2.1 6.3 37.6 1.1 7.2 6.2 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA CLZ PF16526.3 001284076.1_29523001_1 - 2.5 8.4 37.4 0.049 13.8 5.4 4.7 2 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IncA PF04156.12 001284076.1_29523001_1 - 2.7 7.6 50.2 2.9e+02 1.0 33.7 2.9 1 1 1 2 2 2 0 IncA protein TraF_2 PF13729.4 001284076.1_29523001_1 - 2.9 7.1 6.5 7.8 5.6 0.6 2.2 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein DUF948 PF06103.9 001284076.1_29523001_1 - 3.6 7.8 13.6 1.3 9.2 0.4 4.1 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.6 001284076.1_29523001_1 - 4.2 7.3 41.2 0.12 12.3 11.3 3.7 1 1 3 4 4 3 0 Afadin- and alpha -actinin-Binding SNARE PF05739.17 001284076.1_29523001_1 - 4.6 7.2 4.9 2.6 8.0 0.1 2.7 3 0 0 3 3 2 0 SNARE domain Lebercilin PF15619.4 001284076.1_29523001_1 - 5.1 6.6 51.9 0.58 9.6 13.3 3.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.10 001284076.1_29523001_1 - 6.6 4.6 42.9 11 3.9 42.9 1.2 1 0 0 1 1 1 0 HOOK protein GAS PF13851.4 001284076.1_29523001_1 - 7.2 5.8 47.7 0.14 11.4 5.4 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.4 001284076.1_29523001_1 - 7.5 4.9 36.3 1.7 7.1 4.7 2.1 1 1 1 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.10 001284076.1_29523001_1 - 8.5 6.3 56.2 2.1 8.3 19.1 4.0 1 1 3 4 4 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.9 001284076.1_29523001_1 - 8.7 6.3 50.4 3 7.9 9.0 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.13 001284076.1_29523001_1 - 9.2 5.6 30.7 7.1 6.0 15.1 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Pkinase PF00069.23 001280064.1_39726001_1 - 9.3e-77 257.8 0.1 1.6e-76 257.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.15 001280064.1_39726001_1 - 3.9e-36 124.5 0.0 5.5e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.27 001280064.1_39726001_1 - 1.3e-14 54.4 0.1 3.2e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.22 001280064.1_39726001_1 - 4.2e-09 36.8 2.6 8.5e-09 35.8 2.6 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.4 001280064.1_39726001_1 - 5.4e-08 32.4 0.0 8.6e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.4 001280064.1_39726001_1 - 0.12 12.7 0.1 0.5 10.7 0.2 2.1 2 1 0 2 2 2 0 Pleckstrin homology domain bZIP_1 PF00170.19 001279953.1_39724001_1 - 1.1e-12 47.8 6.5 1.7e-12 47.1 6.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001279953.1_39724001_1 - 7.3e-09 35.4 6.8 1.6e-08 34.4 6.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.15 001279953.1_39724001_1 - 0.0068 16.8 6.7 0.015 15.7 6.7 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor PRY PF13765.4 001319372.1_29527001_1 - 1.3e-20 72.6 0.1 2.7e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.26 001319372.1_29527001_1 - 1.6e-05 24.9 0.1 3e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 SPRY domain V-set PF07686.15 001319372.1_29527001_2 - 5.9e-13 48.8 0.0 4e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.4 001319372.1_29527001_2 - 3e-06 27.6 0.0 0.0071 16.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.14 001319372.1_29527001_2 - 3.3e-06 26.9 0.0 0.0045 16.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.23 001319372.1_29527001_2 - 0.002 18.1 0.0 0.65 10.1 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.10 001319372.1_29527001_2 - 0.054 13.4 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ribosomal_S17e PF00833.16 001322790.2_39721001_3 - 4.4e-70 233.1 0.6 5.1e-70 232.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal S17 PAP2 PF01569.19 001319555.1_29523001_3 - 2.5e-13 49.9 3.7 3.9e-13 49.2 3.7 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.4 001319555.1_29523001_3 - 6.2e-05 22.6 6.3 0.0001 21.9 6.3 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.4 001319555.1_29523001_3 - 0.025 14.9 1.0 0.047 14.1 1.0 1.4 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Pkinase PF00069.23 001319391.1_29524001_3 - 2.7e-54 184.2 0.1 5e-54 183.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.15 001319391.1_29524001_3 - 1.1e-24 87.1 0.1 3.7e-24 85.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ras PF00071.20 001284847.1_29525001_3 - 1.5e-24 86.3 0.1 1.8e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.11 001284847.1_29525001_3 - 5.3e-10 39.4 0.0 9.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.19 001284847.1_29525001_3 - 1.4e-06 27.7 0.0 1.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.21 001284847.1_29525001_3 - 0.00021 21.2 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.25 001284847.1_29525001_3 - 0.0011 18.4 0.1 0.062 12.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.21 001284847.1_29525001_3 - 0.0027 17.7 0.1 0.0064 16.4 0.1 1.6 1 1 0 1 1 1 1 Dynamin family DUF2121 PF09894.7 001284847.1_29525001_3 - 0.04 13.3 0.1 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) DUF258 PF03193.14 001284847.1_29525001_3 - 0.068 12.9 0.2 3.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Secretogranin_V PF05281.9 001284899.1_29523001_2 - 2.4e-12 46.8 0.2 1.8e-09 37.5 0.1 2.1 1 1 1 2 2 2 2 Neuroendocrine protein 7B2 precursor (Secretogranin V) Fer2_3 PF13085.4 001284646.1_29523001_2 - 1.4e-33 115.0 0.0 2.4e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.4 001284646.1_29523001_2 - 1.3e-09 38.3 4.8 1.3e-09 38.3 4.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.4 001284646.1_29523001_2 - 3.2e-08 33.8 9.1 4.6e-07 30.1 7.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.4 001284646.1_29523001_2 - 9.2e-07 28.7 2.5 9.2e-07 28.7 2.5 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.25 001284646.1_29523001_2 - 0.0017 18.2 3.4 0.0034 17.2 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.4 001284646.1_29523001_2 - 0.0056 16.7 4.9 0.0056 16.7 4.9 2.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.5 001284646.1_29523001_2 - 0.035 14.6 6.9 0.035 14.6 6.9 3.0 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.4 001284646.1_29523001_2 - 0.36 11.7 9.2 3 8.7 1.6 3.1 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Glyco_hydro_56 PF01630.16 001280198.1_39724001_1 - 1.1e-121 405.9 0.0 1.3e-121 405.6 0.0 1.1 1 0 0 1 1 1 1 Hyaluronidase EGF_2 PF07974.11 001280198.1_39724001_1 - 0.0022 18.2 1.0 0.0022 18.2 1.0 2.6 2 1 0 2 2 2 1 EGF-like domain EGF PF00008.25 001280198.1_39724001_1 - 0.17 12.1 4.6 1.1 9.5 4.6 2.5 1 1 0 1 1 1 0 EGF-like domain Peptidase_M29 PF02073.13 001280198.1_39724001_1 - 0.32 9.6 0.3 0.46 9.1 0.3 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) LAMTOR PF15454.4 001283629.1_29523001_3 - 3.5e-20 72.3 0.3 5.9e-20 71.5 0.3 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Ribosomal_S17e PF00833.16 001265804.1_29622001_2 - 4.9e-70 233.0 0.6 5.9e-70 232.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal S17 WD40 PF00400.30 001283674.1_29524001_3 - 1.5e-26 92.0 21.5 2.8e-06 27.8 0.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001283674.1_29524001_3 - 8.4e-20 70.7 8.4 1.1e-06 28.8 0.2 5.2 3 2 1 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001283674.1_29524001_3 - 3.4e-07 30.2 0.0 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.3 001283674.1_29524001_3 - 0.00056 18.8 0.5 0.058 12.2 0.2 3.5 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.3 001283674.1_29524001_3 - 0.049 12.1 0.0 0.089 11.3 0.0 1.3 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin DUF4807 PF16065.3 001319513.1_29527001_3 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) zf-C4 PF00105.16 001285306.1_29525001_3 - 2.9e-30 104.4 15.9 6.1e-30 103.4 15.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.28 001285306.1_29525001_3 - 1.8e-17 63.5 0.1 5.5e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DUF4679 PF15728.3 001328315.1_39725001_2 - 6.3e-217 720.1 48.1 8e-217 719.8 48.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4679) Ribosomal_S8e PF01201.20 001246638.2_39723001_1 - 3.1e-47 160.1 15.0 3.2e-46 156.8 15.0 2.3 1 1 0 1 1 1 1 Ribosomal protein S8e TPR_1 PF00515.26 001280212.1_39726001_3 - 1.4e-43 144.8 18.2 1.7e-06 27.5 0.1 10.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.15 001280212.1_39726001_3 - 1e-41 137.6 10.0 3.4e-05 23.5 0.2 11.9 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_12 PF13424.4 001280212.1_39726001_3 - 5.9e-35 119.3 11.4 3.2e-08 33.6 0.0 8.1 5 2 4 9 9 8 7 Tetratricopeptide repeat TPR_7 PF13176.4 001280212.1_39726001_3 - 9.2e-31 103.4 7.9 0.00027 20.6 0.0 10.9 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.4 001280212.1_39726001_3 - 4.7e-28 94.9 30.1 0.00098 19.0 0.1 11.7 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_19 PF14559.4 001280212.1_39726001_3 - 3.4e-24 85.0 6.1 9.7e-05 22.7 0.4 7.1 5 2 3 8 8 8 7 Tetratricopeptide repeat TPR_6 PF13174.4 001280212.1_39726001_3 - 5e-24 83.2 18.6 0.027 15.0 0.0 11.8 11 1 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.4 001280212.1_39726001_3 - 4.2e-22 78.4 0.1 5.3e-06 26.9 0.0 7.5 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.4 001280212.1_39726001_3 - 3.6e-18 64.5 0.0 0.058 14.1 0.0 9.2 4 1 5 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.4 001280212.1_39726001_3 - 1.1e-16 60.1 17.0 1.2e-06 28.0 0.4 8.3 8 1 1 9 9 9 5 TPR repeat ANAPC3 PF12895.5 001280212.1_39726001_3 - 3.6e-16 59.0 18.6 1.3e-07 31.5 1.2 6.3 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.4 001280212.1_39726001_3 - 6.6e-11 41.6 17.0 0.65 9.8 0.1 10.4 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_9 PF13371.4 001280212.1_39726001_3 - 2.5e-08 33.8 0.0 0.073 13.1 0.0 5.2 5 2 2 7 7 5 2 Tetratricopeptide repeat TPR_21 PF09976.7 001280212.1_39726001_3 - 1.7e-06 27.8 8.4 0.00016 21.4 4.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_17 PF13431.4 001280212.1_39726001_3 - 1.8e-06 27.8 19.3 0.2 12.0 0.3 9.0 10 0 0 10 10 9 1 Tetratricopeptide repeat DUF3808 PF10300.7 001280212.1_39726001_3 - 3.4e-06 25.9 0.4 3.4e-06 25.9 0.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) MIT PF04212.16 001280212.1_39726001_3 - 0.00026 20.9 21.4 9.7 6.2 0.4 9.3 8 1 1 9 9 8 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.4 001280212.1_39726001_3 - 0.0005 19.2 7.5 0.012 14.7 0.4 4.1 2 1 2 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.7 001280212.1_39726001_3 - 0.0074 15.8 16.4 0.1 12.1 0.0 6.5 4 3 4 8 8 8 1 26S proteasome subunit RPN7 PPR PF01535.18 001280212.1_39726001_3 - 0.011 15.8 5.2 79 3.7 0.0 6.3 7 0 0 7 7 6 0 PPR repeat Wzy_C_2 PF11846.6 001280212.1_39726001_3 - 0.019 14.8 0.2 2.4 7.9 0.0 3.4 3 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Sel1 PF08238.10 001280212.1_39726001_3 - 0.02 15.5 14.6 3.7 8.2 0.0 6.6 7 0 0 7 7 6 0 Sel1 repeat BTAD PF03704.15 001280212.1_39726001_3 - 0.024 14.9 0.3 25 5.1 0.0 4.8 3 2 1 4 4 4 0 Bacterial transcriptional activator domain ELYS PF13934.4 001280212.1_39726001_3 - 0.051 13.4 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Nuclear pore complex assembly HrpB1_HrpK PF09613.8 001280212.1_39726001_3 - 0.054 13.0 0.0 6.7 6.2 0.0 3.4 4 0 0 4 4 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Foie-gras_1 PF11817.6 001280212.1_39726001_3 - 0.06 12.8 7.2 10 5.5 0.0 4.6 4 1 1 5 5 5 0 Foie gras liver health family 1 FumaraseC_C PF10415.7 001280212.1_39726001_3 - 0.17 12.2 1.9 0.41 11.0 0.1 2.6 2 0 0 2 2 2 0 Fumarase C C-terminus DUF4810 PF16068.3 001280212.1_39726001_3 - 0.21 12.0 6.2 13 6.3 0.0 5.5 6 0 0 6 6 5 0 Domain of unknown function (DUF4810) Fis1_TPR_C PF14853.4 001280212.1_39726001_3 - 0.25 11.3 11.0 18 5.4 0.2 5.5 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.4 001280212.1_39726001_3 - 0.37 11.1 3.8 13 6.1 1.1 3.1 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation EIF_2_alpha PF07541.10 001283137.1_29525001_2 - 2.2e-36 124.4 0.0 3.6e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.21 001283137.1_29525001_2 - 4.5e-15 55.6 0.7 9.9e-15 54.5 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain CLTH PF10607.7 001261593.1_29624001_2 - 7.8e-33 113.3 0.0 1.9e-32 112.0 0.0 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.4 001261593.1_29624001_2 - 4.8e-05 23.1 0.2 0.00012 21.9 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.10 001261593.1_29624001_2 - 0.0047 16.2 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.4 001261593.1_29624001_2 - 0.03 14.4 0.1 0.11 12.7 0.1 2.1 1 0 0 1 1 1 0 Ring finger domain Sec15 PF04091.10 001261593.1_29624001_2 - 0.041 13.2 0.1 0.063 12.6 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF837 PF05769.9 001257773.1_29626001_2 - 2.7e-75 252.2 25.3 3.4e-75 251.8 25.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF837) WD40 PF00400.30 001171059.1_29624001_1 - 6.7e-29 99.4 12.8 0.00014 22.5 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.5 001171059.1_29624001_1 - 2.8e-16 59.5 0.1 0.0016 18.5 0.0 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.9 001171059.1_29624001_1 - 4.9e-05 23.2 0.0 0.03 14.1 0.0 2.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.4 001171059.1_29624001_1 - 0.001 18.6 1.0 0.0083 15.6 0.9 2.3 1 1 0 1 1 1 1 PQQ-like domain Ge1_WD40 PF16529.3 001171059.1_29624001_1 - 0.0023 16.8 0.1 0.078 11.8 0.0 2.9 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.3 001171059.1_29624001_1 - 0.0032 16.7 0.0 0.59 9.3 0.0 3.2 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.6 001171059.1_29624001_1 - 0.0058 15.2 0.1 0.58 8.6 0.1 3.1 3 0 0 3 3 3 1 Nucleoporin Nup120/160 DUF5046 PF16465.3 001171059.1_29624001_1 - 0.032 13.6 0.1 1 8.6 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) RAB3GAP2_N PF14655.4 001171059.1_29624001_1 - 0.14 11.2 0.0 0.53 9.3 0.0 1.9 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.19 001171059.1_29624001_1 - 3.2 7.7 7.8 30 4.6 0.1 4.6 5 0 0 5 5 5 0 PQQ enzyme repeat MAGE_N PF12440.6 001280456.1_39724001_1 - 1.3e-17 64.1 13.4 1.3e-17 64.1 13.4 2.4 3 0 0 3 3 3 1 Melanoma associated antigen family N terminal MAGE PF01454.17 001280456.1_39724001_1 - 2.5e-11 43.5 0.2 3e-08 33.5 0.0 2.8 2 1 0 2 2 2 1 MAGE family ELM2 PF01448.22 001257926.1_29627001_1 - 1.5e-08 35.1 1.8 6.7e-08 33.1 0.1 2.6 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.29 001257926.1_29627001_1 - 0.00082 19.3 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rad1 PF02144.14 001280206.2_39724001_3 - 1.4e-83 280.0 1.2 1.6e-83 279.7 1.2 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 NDK PF00334.17 001204511.1_39722001_1 - 9.3e-55 184.2 0.0 1.1e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pro_isomerase PF00160.19 001284774.1_29522001_3 - 1e-46 159.0 0.2 1.2e-46 158.7 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SET PF00856.26 001266503.1_29625001_1 - 5.7e-18 65.7 6.9 6.2e-18 65.6 0.5 3.0 2 2 0 2 2 2 1 SET domain EZH2_WD-Binding PF11616.6 001266503.1_29625001_1 - 1.1e-16 60.4 2.5 2.7e-16 59.2 2.5 1.7 1 0 0 1 1 1 1 WD repeat binding protein EZH2 CDC45 PF02724.12 001266503.1_29625001_1 - 5.5 5.0 8.0 7.4 4.6 2.6 2.1 2 0 0 2 2 2 0 CDC45-like protein ArfGap PF01412.16 001261226.1_29626001_1 - 1.5e-32 111.9 0.1 3.1e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.11 001261226.1_29626001_1 - 0.29 11.2 4.3 0.18 11.8 1.5 2.1 2 0 0 2 2 2 0 Piccolo Zn-finger B12D PF06522.9 001097468.2_49822001_1 - 2.4e-33 113.6 0.0 3.8e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit TIR_2 PF13676.4 001285821.1_29522001_1 - 1.8e-08 34.5 0.0 3.7e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 TIR domain TIR PF01582.18 001285821.1_29522001_1 - 0.00063 19.5 0.0 0.0018 17.9 0.0 1.7 2 0 0 2 2 2 1 TIR domain PH PF00169.27 001194039.2_29627001_2 - 0.00085 19.7 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF3106 PF11304.6 001194039.2_29627001_2 - 0.051 13.9 0.7 0.2 12.0 0.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Cofilin_ADF PF00241.18 001284960.1_29523001_2 - 4.7e-29 101.0 1.3 6.7e-29 100.5 1.3 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mnd1 PF03962.13 001285079.1_29523001_1 - 0.0042 16.9 1.7 0.0042 16.9 1.7 2.1 2 0 0 2 2 2 1 Mnd1 family AMP-binding_C_2 PF14535.4 001285079.1_29523001_1 - 0.18 12.0 2.4 2.2 8.5 2.4 2.3 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain EHN PF06441.10 001284802.1_29525001_1 - 3.3e-33 114.0 0.4 3.3e-33 114.0 0.4 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.18 001284802.1_29525001_1 - 1.3e-32 113.3 0.0 1.9e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold EOS1 PF12326.6 001284802.1_29525001_1 - 0.028 14.2 0.3 0.038 13.8 0.3 1.3 1 0 0 1 1 1 0 N-glycosylation protein FHIPEP PF00771.18 001284802.1_29525001_1 - 0.19 10.0 1.5 0.29 9.4 1.5 1.2 1 0 0 1 1 1 0 FHIPEP family RNA_pol_Rpc4 PF05132.12 001284802.1_29525001_1 - 2.9 8.2 15.8 4.4 7.6 15.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1510 PF07423.9 001284802.1_29525001_1 - 4.4 6.6 18.8 6.3 6.0 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TGF_beta PF00019.18 001284802.1_29525001_2 - 1.2e-06 29.2 3.0 1.2e-06 29.2 3.0 2.0 2 0 0 2 2 2 1 Transforming growth factor beta like domain RNA_pol_Rpc4 PF05132.12 001284802.1_29525001_2 - 2.1 8.6 12.8 3 8.1 12.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 NDK PF00334.17 001204512.1_39722001_3 - 4e-55 185.4 0.0 4.8e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SUFU_C PF12470.6 001287734.1_29524001_2 - 2.4e-81 272.6 0.0 2.5e-76 256.2 0.0 2.2 2 0 0 2 2 2 2 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.11 001287734.1_29524001_2 - 8.9e-51 172.2 0.0 1.3e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) HATPase_c_3 PF13589.4 001261599.1_29627001_2 - 1.1e-27 96.4 0.0 2.5e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.13 001261599.1_29627001_2 - 2.1e-15 56.3 4.0 4.4e-15 55.3 4.0 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger XhlA PF10779.7 001261599.1_29627001_2 - 5.8 7.1 12.2 24 5.0 0.6 3.7 3 0 0 3 3 3 0 Haemolysin XhlA Ribosomal_L44 PF00935.17 001242635.1_39722001_2 - 1.4e-39 134.3 10.1 2.6e-39 133.4 10.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.9 001242635.1_39722001_2 - 0.011 15.8 0.4 0.023 14.7 0.4 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like SBP PF03110.12 001242635.1_39722001_2 - 0.045 13.8 1.7 0.09 12.9 1.7 1.4 1 0 0 1 1 1 0 SBP domain 4HBT PF03061.20 001319347.1_29524001_1 - 4e-32 110.3 3.2 4.1e-16 59.0 0.3 2.3 2 0 0 2 2 2 2 Thioesterase superfamily tRNA_anti-codon PF01336.23 001319347.1_29524001_1 - 0.0018 18.1 0.0 0.027 14.3 0.0 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain NINJA_B PF16136.3 001319347.1_29524001_1 - 0.0069 16.6 0.6 0.0069 16.6 0.6 3.2 3 0 0 3 3 3 1 Putative nuclear localisation signal SR-25 PF10500.7 001319347.1_29524001_1 - 0.069 12.6 32.9 0.19 11.2 32.9 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.9 001319347.1_29524001_1 - 1.8 8.5 36.7 5 7.0 36.7 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HA2 PF04408.21 001319347.1_29524001_1 - 6.2 7.1 6.8 80 3.5 5.2 3.0 3 0 0 3 3 3 0 Helicase associated domain (HA2) DUF3807 PF12720.5 001319347.1_29524001_3 - 2.7 8.1 16.3 4 7.6 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.15 001319347.1_29524001_3 - 9.6 4.7 5.5 12 4.4 5.5 1.1 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.20 001284068.1_29523001_2 - 1.6e-16 59.7 0.0 2.3e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.21 001284068.1_29523001_2 - 0.00068 19.5 7.7 0.0018 18.2 7.7 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.4 001284068.1_29523001_2 - 0.00071 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.4 001284068.1_29523001_2 - 0.0013 18.5 2.6 0.0042 16.9 2.6 1.9 1 0 0 1 1 1 1 Zinc knuckle SCNM1_acidic PF15805.3 001319501.1_29523001_3 - 2.2e-25 88.0 0.6 4.3e-25 87.0 0.6 1.4 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 zf-SCNM1 PF15803.3 001319501.1_29523001_3 - 3.1e-15 55.3 1.5 6.3e-15 54.4 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of sodium channel modifier 1 Kelch_1 PF01344.23 001284157.1_29525001_2 - 1.2e-89 293.5 19.9 5.4e-16 57.8 0.4 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.4 001284157.1_29525001_2 - 1.8e-52 173.8 7.0 2.3e-09 37.1 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.13 001284157.1_29525001_2 - 4.6e-38 129.3 1.0 5.4e-38 129.1 0.1 1.6 2 0 0 2 2 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.4 001284157.1_29525001_2 - 1.4e-37 127.3 5.1 3.2e-06 26.9 0.0 6.3 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.4 001284157.1_29525001_2 - 1.9e-33 114.0 14.9 8.8e-06 25.7 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.29 001284157.1_29525001_2 - 1.2e-32 112.3 0.3 2.4e-32 111.3 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.13 001284157.1_29525001_2 - 6.7e-30 101.8 6.2 1.5e-06 27.8 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.4 001284157.1_29525001_2 - 4.2e-05 23.3 3.6 2.7 8.0 0.1 5.4 6 0 0 6 6 6 2 Kelch motif Glyoxal_oxid_N PF07250.9 001284157.1_29525001_2 - 0.063 12.3 0.2 1.3 8.0 0.0 2.3 2 1 0 2 2 2 0 Glyoxal oxidase N-terminus Glu_cyclase_2 PF05096.10 001284157.1_29525001_2 - 0.07 12.4 0.0 27 3.9 0.0 2.8 1 1 1 3 3 3 0 Glutamine cyclotransferase XPA_C PF05181.10 001284157.1_29525001_2 - 0.081 12.8 0.6 6.8 6.6 0.0 3.1 4 0 0 4 4 4 0 XPA protein C-terminus APP_E2 PF12925.5 001280497.1_39726001_3 - 6.1e-69 231.4 17.3 8.2e-69 231.0 16.2 1.8 2 0 0 2 2 2 1 E2 domain of amyloid precursor protein APP_N PF02177.14 001280497.1_39726001_3 - 4.9e-41 139.0 1.2 4.9e-41 139.0 1.2 2.0 2 0 0 2 2 2 1 Amyloid A4 N-terminal heparin-binding APP_amyloid PF10515.7 001280497.1_39726001_3 - 6.2e-25 87.4 1.7 1.1e-24 86.5 0.2 2.4 2 0 0 2 2 2 1 beta-amyloid precursor protein C-terminus APP_Cu_bd PF12924.5 001280497.1_39726001_3 - 7.7e-24 84.1 6.7 7.7e-24 84.1 6.7 2.5 3 0 0 3 3 3 1 Copper-binding of amyloid precursor, CuBD Kunitz_BPTI PF00014.21 001280497.1_39726001_3 - 9.2e-20 70.5 4.2 9.2e-20 70.5 4.2 2.4 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain VHL_C PF17211.1 001280497.1_39726001_3 - 0.13 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 VHL box domain Activator-TraM PF11657.6 001280497.1_39726001_3 - 3.5 7.3 6.9 7.6 6.2 6.9 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM Glyco_hydro_31 PF01055.24 001257679.1_29628001_1 - 6e-151 503.4 3.4 8.3e-151 502.9 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.4 001257679.1_29628001_1 - 1.2e-18 67.0 0.5 3.3e-18 65.6 0.2 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.2 001257679.1_29628001_1 - 0.0015 18.6 0.0 0.0049 17.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5110) SMI1_KNR4 PF09346.8 001260587.2_29624001_3 - 0.0021 18.3 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SlyX PF04102.10 001319487.1_29523001_3 - 0.0087 16.5 23.4 0.081 13.4 2.0 3.7 2 1 1 3 3 3 2 SlyX HMMR_N PF15905.3 001319487.1_29523001_3 - 0.016 14.6 26.0 0.19 11.1 18.4 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PspA_IM30 PF04012.10 001319487.1_29523001_3 - 0.025 14.0 2.0 0.025 14.0 2.0 3.1 2 1 0 3 3 3 0 PspA/IM30 family Fib_alpha PF08702.8 001319487.1_29523001_3 - 0.42 10.6 18.4 0.45 10.6 8.4 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF16 PF01519.14 001319487.1_29523001_3 - 3.1 8.2 24.4 1.5 9.2 0.6 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 ATG16 PF08614.9 001319487.1_29523001_3 - 5.6 6.9 31.4 1.5 8.8 0.9 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Streptin-Immun PF11083.6 001319487.1_29523001_3 - 6.1 7.2 12.7 0.057 13.7 2.0 2.8 2 1 2 4 4 4 0 Lantibiotic streptin immunity protein DUF812 PF05667.9 001319487.1_29523001_3 - 8.4 5.0 23.7 1.6 7.4 16.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Laminin_II PF06009.10 001319487.1_29523001_3 - 10 6.0 21.8 0.084 12.8 3.4 3.0 2 1 1 3 3 3 0 Laminin Domain II tRNA-synt_1c PF00749.19 001280419.1_39725001_3 - 9.6e-118 392.5 0.0 1.3e-117 392.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.13 001280419.1_39725001_3 - 1.8e-50 171.0 0.0 3.2e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.16 001280419.1_39725001_3 - 2e-42 144.9 0.0 3.6e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.13 001280419.1_39725001_3 - 3.8e-15 56.4 4.7 1.2e-07 32.4 1.0 2.5 1 1 1 2 2 2 2 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF5136 PF17199.2 001280419.1_39725001_3 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) DEAD PF00270.27 001319400.1_29524001_1 - 1.7e-29 102.7 0.0 3.8e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.29 001319400.1_29524001_1 - 3.9e-27 94.7 0.1 7.8e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Met_10 PF02475.14 001279905.1_39724001_2 - 4.5e-63 212.5 0.0 1.2e-62 211.1 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_15 PF09445.8 001279905.1_39724001_2 - 0.001 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.13 001279905.1_39724001_2 - 0.0071 15.9 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase tRNA_U5-meth_tr PF05958.9 001279905.1_39724001_2 - 0.019 13.8 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Tmemb_185A PF10269.7 001242322.2_39729001_1 - 4.3e-59 200.1 27.8 7.4e-59 199.3 27.8 1.4 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein bZIP_Maf PF03131.15 001194758.2_29624001_1 - 3.3e-17 62.6 4.8 5.9e-17 61.8 4.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.19 001194758.2_29624001_1 - 1.4e-07 31.4 10.3 2.4e-07 30.6 10.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.13 001194758.2_29624001_1 - 0.0013 18.6 12.2 0.0028 17.6 12.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Peptidase_Mx PF15887.3 001194758.2_29624001_1 - 0.027 13.7 0.1 0.054 12.8 0.1 1.4 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase # # Program: hmmscan # Version: 3.1b2 (February 2015) # Pipeline mode: SCAN # Query file: /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/simple/part7/wd/simple7.p.fa # Target file: /home/yduan/database/Pfam/Pfam-A.hmm # Option settings: hmmscan -o /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/simple/part7/hmmscan.outm --tblout /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/simple/part7/hmmscan.t.out /home/yduan/database/Pfam/Pfam-A.hmm /home/yduan/work_file/lncRNAdb/methods_assement/prediction_results/smallRNE/simple/part7/wd/simple7.p.fa # Current dir: /home/yduan/work_file/lncRNAdb/methods_assement # Date: Tue Jul 10 05:31:56 2018 # [ok]