XLOC_000113 (plk1)


Basic Information

Item Value
gene id XLOC_000113
gene name plk1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 9153141 ~ 9161843 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000207
ggcgGAGGCAACGAATCGAGCACAATTCAAAAAGTAGCAGCGATTCACTGCATTCCCAACCGAGCTGCGGGCCGACGCGCTTCACCACCGCCCGTTTACATCCACGAAATTCGACAAATGCGGTGAATATACGGCGTTTAGATACTTTGTTGTGCCTTTTTGTCTTGGCTGGCGGTATTATTTGAATGCGGATTTCAGCGGAGGAGTGAAGTACTGCGTGTTGTTTACGGATAAAGGAGCAGGAAACATCGCCTCGGTTGTTTATTTTTCAGGACGTTAGGGTGTATTTTTGTACTTAAGAGCATTTGTAGTGTACAACGATGAGTGCTGCAATTGCAAAGCCATCGGCGAAGCCATCGGCTCACGTCGATCCCAAATCTGCTCCTCTGAAAGAGATTCCCGACGTTCTGGTGGATCCGAGAACCATGAAGAGATACATGAGAGGTCGCTTTTTGGGAAAAGGAGGATTCGCCAAATGCTACGAAATCACAGATATGGACACAAAAGAGGTCTTCGCTGGGAAAGTTGTGCCGAAGTCGATGCTGCTGAAGCCGCACCAGAAGGAGAAAATGAGCACAGAAATCGCCATTCACAAAAGTCTCGATAATCCGCATGTTGTGGGCTTTCACGGGTTCTTTGAGGATGATGACTTCGTGTATGTGGTGCTGGAAATCTGTCGCAGAAGGTCTCTCCTTGAATTGCACAAAAGGAGGAAGGCAGTGACTGAGCCTGAGGCCCGATACTTCATGCGCCAGACTATTCAGGGTGTTCAGTACTTGCACAACAACAGAGTCATTCACCGTGATCTCAAACTTGGGAATCTGTTCCTCAATGATGACATGGATGTGAAGATCGGTGACTTTGGTTTAGCCACTAAGATTGAGTTTGATGGGGAGCGAAAGAAGACCCTTTGTGGCACTCCAAACTACATTGCTCCTGAGGTGCTCTGCAAGAAAGGCCACAGCTTTGAAGTTGACATTTGGTCACTAGGATGCATTCTATACACACTGCTGGTTGGAAAGCCTCCATTTGAGACATCCTGTCTGAAAGAGACCTACATTAGGATTAAGAAGAATGAGTACTCAGTTCCTAGAcacattaATCCAGTTGCATCTGCTTTGATTCGTCGGATGCTGCACGCTGACCCTACACTCAGACCTTCTGTAGCTGAACTGCTGACTGATGAGTTTTTCACCTCTGGTTATGCACCCATGCGGCTGCCCACTTCCTGTCTCACTGTTCCTCCCAGGTTCTCCATCGCCCCCTCCAGCCTGGATCCTGCCCTCCTCCGCAAACCTCTCTCATCACTTAATAAAGGCACAGATAGTCCAATTGAGAAAATGGGGAAAATGGATCAGCCACAAAGAGAAGATCTGCAACAAAGAGATGGACCAGAGCAGCCTGACACTCACCTAACTGACATGCTGCAGCAGCTGGCTGTCGTCAATGCAGCCAAGCCGTCTGATAGAGACTTTATTAGACAAGAGGAAGCTGAAGACCCTGCTTGTATTCCTGTCTTCTGGATTAGTAAATGGGTTGACTACTCTGACAAATATGGCCTTGgttaCCAGTTGTCTGATAACAGTGTAGGTGTTCTGTTCAATGATTCCACACGGTTGATCATGTGTGCTGACGGTGATAGCCTGCAGTACATCGATCGCAACTCTCTAGAATCCTACCTCAGTGTTCGCTCGTATCCCTCTGCACTCTCCAAAAAGATTACACTCCTTAAGTACTTCAGGAATTACATGAGTGAGCACTTGCTGAAGGCTGGAGCGAATATAACTCCTCGGGAAGGGGATGAACTGACCCGATTGCCTTACCTTCGCCACTGGTTCCGCACAAAGAGTGCTATTGTGCTACACCTGAGTAATGGGACTGTGCAAATCAATTTTTTCCAGGATCACACTAAGCTTATTTTGTGTCCACTAATGGGAGCAGTGACGTACATCAATGAGAAGCGAGAGTTTTACACCTACAAGATGACCTTAATCGAGGAGTTCGGCTGCTGTAAAGAGTTGGCTAGCCGTTTGCGCTATGCTCGCAACATGGTGGAGAAGCTCATGGCCTGCAAAAGCAGCACAACAGCTGCTACTTCAGCACGCTAACCCACTGACGTCATAAATTGTATAGCTATGAGTTCACCATCGGCTCTCACTTGAGTCTGAGGGCCCGTAAATATTACTACAGCAAAACTTGAACAGTTTTCTGAGTTCTACACTATGATGTCCTCTTCTGGATCTGTTTACTCTCTCTCGCTGTCGTTTGTTCATCAGGGTTGCACATCTGTGGCCATCTCTGTATCATGTGAATGCTCTTgtacatgttttaatattttagatgCTGTTTATCTGTCCTCTGTTCTTTGTATAAAAGCTTTTGGATGAGAATCTTTTAACGTGTAAGAATATTTGAAATAATTTGGTATTCCAAAAATAAAGATCTTTTTAGACAAAATTTTGGATTGTTAGATACTATTGAGAAATACAAGTTTATATTCgagtgtttaattaaaatattcatgTTTGGAAAGTTAAA
>TCONS_00000208
AAATTGTTGTTCAAACGAACTGCGTCTAAACGTCGCTTTTGTCGTCAAATTTTAGTTCTCTCCTTGAATTGCACAAAAGGAGGAAGGCAGTGACTGAGCCTGAGGCCCGATACTTCATGCGCCAGACTATTCAGGGTGTTCAGTACTTGCACAACAACAGAGTCATTCACCGTGATCTCAAACTTGGGAATCTGTTCCTCAATGATGACATGGATGTGAAGATCGGTGACTTTGGTTTAGCCACTAAGATTGAGTTTGATGGGGAGCGAAAGAAGACCCTTTGTGGCACTCCAAACTACATTGCTCCTGAGGTGCTCTGCAAGAAAGGCCACAGCTTT
>TCONS_00003033
AAATTGTTGTTCAAACGAACTGCGTCTAAACGTCGCTTTTGTCGTCAAATTTTAGTTCTCTCCTTGAATTGCACAAAAGGAGGAAGGCAGTGACTGAGCCTGAGGCCCGATACTTCATGCGCCAGACTATTCAGGGTGTTCAGTACTTGCACAACAACAGAGTCATTCACCGTGATCTCAAACTTGGGAATCTGTTCCTCAATGATGACATGGATGTGAAGATCGGTGACTTTGGTTTAGCCACTAAGATTGAGTTTGATGGGGAGCGAAAGAAGACCCTTTGTGGCACTCCAAACTACATTGCTCCTGAGGTGCTCTGCAAGAAAGGCCACAGCTTTGAAGTTGACATTTGGTCACTAGGATGCATTCTTAATTTCTTTTCTTTATCAGATACACACTGCTGGTTGGAAAGCCTCCATTTGAGACATCCTGTCTGAAAGAGACCTACATTAGGATTAAGAAGAATGAGTAC
>TCONS_00000209
GTACTTGCACAACAACAGAGTCATTCACCGTGATCTCAAACTTGGGAATCTGTTCCTCAATGATGACATGGATGTGAAGATCGGTGACTTTGGTTTAGCCACTAAGATTGAGTTTGATGGGGAGCGAAAGAAGACCCTTTGTGGCACTCCAAACTACATTGCTCCTGAGGTGCTCTGCAAGAAAGGCCACAGCTTTGAAGTTGACATTTGGTCACTAGGATGCATTCTTAATTTCTTTTCTTTATCAGATACACACTGCTGGTTGGAAAGCCTCCATTTGAGACATCCTGTCTGAAAGAGACCTACATTAGGATTAAGAAGAATGAGTAC
>TCONS_00000210
ACAGAGGAAGCTGAAGACCCTGCTTGTATTCCTGTCTTCTGGATTAGTAAATGGGTTGACTACTCTGACAAATATGGCCTTGgttaCCAGTTGTCTGATAACAGTGTAGGTGTTCTGTTCAATGATTCCACACGGTTGATCATGTGTGCTGACGGTGATAGCCTGCAGTACATCGATCGCAACTCTCTAGAATCCTACCTCAGTGTTCGCTCGTATCCCTCTGCACTCTCCAAAAAGATTACACTCCTTAAGTACTTCAGGAATTACATGAGTGAGCACTTGCTGAAGGCTGGAGCGAATATAACTCCTCGGGAAGGGGATGAACTGACCCGATTGCCTTACCTTCGCCACTGGTTCCGCACAAAGAGTGCTATTGTGCTACACCTGAGTAATGGGACTGTGCAAATCAATTTTTTCCAGGATCACACTAAGCTTATTTTGTGTCCACTAATGGGAGCAGTGACGTACATCAATGAGAAGCGAGAGTTTTACACCTACAAGATGACCTTAATCGAGGAGTTCGGCTGCTGTAAAGAGTTGGCTAGCCGTTTGCGCTATGCTCGCAACATGGTGGAGAAGCTCATGGCCTGCAAAAGCAGCACAACAGCTGCTACTTCAGCACGCTAACCCACTGACGTCATAAATTGTATAGCTATGAGTTCACCATCGGCTCTCACTTGAGTCTGAGG

Function

symbol description
plk1 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within mitotic cell cycle and retina development in camera-type eye. Predicted to be located in midbody. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in several structures, including immature eye; nervous system; neural tube; pharynx; and tail bud. Human ortholog(s) of this gene implicated in urinary bladder cancer. Orthologous to human PLK1 (polo like kinase 1).

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0032465 regulation of cytokinesis biological_process
GO:0016310 phosphorylation biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0000278 mitotic cell cycle biological_process
GO:0005813 centrosome cellular_component
GO:0000922 spindle pole cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG:

id description
ko04068 FoxO signaling pathway
ko04110 Cell cycle
ko04114 Oocyte meiosis
ko04914 Progesterone-mediated oocyte maturation
ko01001 Protein kinases
ko03036 Chromosome and associated proteins

ZFIN:

id description
ZDB-GENE-021115-7 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within mitotic cell cycle and retina development in camera-type eye. Predicted to be located in midbody. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in several structures, including immature eye; nervous system; neural tube; pharynx; and tail bud. Human ortholog(s) of this gene implicated in urinary bladder cancer. Orthologous to human PLK1 (polo like kinase 1).

Ensembl:

ensembl_id ENSDARG00000058471

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000207 False 2538 mRNA 0.45 11 9153141 9161843
TCONS_00000208 False 338 processed_transcript 0.46 3 9154094 9155273
TCONS_00003033 False 472 lncRNA 0.43 4 9154094 9155521
TCONS_00000209 False 330 processed_transcript 0.43 3 9154993 9155521
TCONS_00000210 True 689 lncRNA 0.47 4 9157376 9161475

Neighbor

gene id symbol gene type direction distance location
XLOC_000112 rasd3 coding upstream 7245 9144958 ~ 9145896 (+)
XLOC_000111 NA coding upstream 20651 9129386 ~ 9132490 (+)
XLOC_000110 cacng3a coding upstream 61206 9082417 ~ 9091935 (+)
XLOC_000109 BX004779.3 coding upstream 78662 9071324 ~ 9074479 (+)
XLOC_000108 prkcba coding upstream 88229 9004719 ~ 9064912 (+)
XLOC_000114 chtf18 coding downstream 37188 9199031 ~ 9227204 (+)
XLOC_000115 chtf18 coding downstream 56805 9218648 ~ 9221616 (+)
XLOC_000116 BX323038.1 coding downstream 116003 9277846 ~ 9285351 (+)
XLOC_000117 uncx4.1 coding downstream 128260 9290103 ~ 9294115 (+)
XLOC_000118 elfn1b coding downstream 395369 9557212 ~ 9712302 (+)
XLOC_000106 NA non-coding upstream 176719 8967479 ~ 8976422 (+)
XLOC_000105 NA non-coding upstream 187202 8950874 ~ 8965939 (+)
XLOC_000100 NA non-coding upstream 562505 8587230 ~ 8590636 (+)
XLOC_000098 AL928650.2 non-coding upstream 575867 8575307 ~ 8577274 (+)
XLOC_000120 NA non-coding downstream 725112 9886955 ~ 9914630 (+)
XLOC_000121 NA non-coding downstream 784821 9946664 ~ 9951873 (+)
XLOC_000133 AL935188.1 non-coding downstream 1201877 10363720 ~ 10363851 (+)
XLOC_000135 NA non-coding downstream 1300201 10462044 ~ 10462882 (+)

Expression


Co-expression Network