CI01000299_03594891_03678552 (ERBB4)



Basic Information


Item Value
gene id CI01000299_03594891_03678552
gene name ERBB4
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information


Item Value
chromosome id CI01000299
NCBI id null
chromosome length 6567443
location 3594891 ~ 3679612 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence


>CI01000299_03594891_03678552.mRNA
TGTGTCCTGGCACTGATAACAAGCTCAGCACGCTGTCTGATTTGGACCAGCAGTACAGAACTCTCCGCCAGTTCTACGAGAACTGTGAGGTGGTCATGGGTAATCTGGAGATCACCAGTATTGAACGGAACCGCAACCTGTCTTTCCTCAAGATACTCGTAAAGGTCATGATTGCTATTCAAATGAAGTCTATCCGTGAGGTGACGGGTTATGTGTTGGTGGCTCTGAACCAGTTTGACTATCTTCCTCTGGAGAACCTGCGGATCATCCGTGGCACTAAACTGTACGAAGGACGCTATGCCCTGTCCATCTTTCTCAACTACAGACGAGATGGACACTTCGGCCTTAGACAACTCGGCCTCAAGAACCTGACAGAAATCCTGAATGGAGGCGTGTATGTGGATCAGAACAAGTTCTTGTGCCATGCTGACACCATCCACTGGAATGACATCATCAAGAACCCTCGTTCTGAGCTTCTGGTTGTTCCTTCGAATAACAGTGGCAGCACATGCAGACGGTGTCACAGATCTTGTAATGGACGTTGCTGGGGTCACCAGGAAGACCAGTGCCAAAGCTTGACAAAGACGGTGTGTGCAGAGCAGTGTGATGGACGCTGTTTTGGTCCATACGTCAGTAACTGCTGCCACCGTGAATGTGCAGGAGGCTGTTTCGGACCCAAAGACACGGACTGCTTTGTATGTCAACTCTTCCTTTATTTTTACCTGATTCTGGATGATTTAATAAAGGCTTGTACCAACTTTAATGACAGCGGGGCCTGTGTGACACAATGTCCTCAGCCATTCGTCTACAATCCAACAACCTTCCAGCTTGAACACAATCCCAACGCCAAATACACATTTGGAGCTTTCTGTGTCAAGAAATGCCCACATAACTTTGTGGTGGATCACAGCTCTTGTGTCAGAGCCTGTCCGAGCAATAAGATGGAAGTTGAGGAAAATCACATAAAGATGTGCATCCCGTGCACTGACATCTGTCCAAAAGTGTGTGATGGTATAGGTACCGGCAGTCTTCAAACGGCTCAAACTGTAGATTCCAGGAACATCGAGAAGTTTGTCAATTGCACCAAAATCAACGGAAACCTAATTTTCCTCATCACGGGCATCAAAGGGGACATGTTTCATGGTATCAGAGCTCTGGATCCTGATCGGCTAAATGTATTCCGCACCGTCAGAGAGATCACAGCTAATGGAGTGAAGCAGCAAAGCAATGTTTTCAGAATGAAACTCGAGCATGGTATTTCTCTGCTGATCCTGAAGCAGAGCTGGATCTCTTCACTGCAGTTCCAGTCTTTGAGAGAGATCAGCGCCGGTAACGTCTACATGACCAACAACAGCCAGCTCTGCTTCTACAATACAGTGAACTGGACCGGTCTGTTCCGCACCAGCACCCAGAGAGCTATGATCAGGAACAACAGGGACCCCAGAGAGTGTATAAACAATGTGTTCGAGTTCATCCAACATTTCACCTCCTCAAGGCAATTCAGCAAAGAATTTTTCAGCTTTCCTGCTTTGAAAGGCAGGGATGTTCGAGAGTACGCCAATGGCTCCGTTTGTGTTGAGTGTGACAGCCAGTGTGAAAAAGCCGGAGAGAAAAGTTTGACCTGCCATGGCCCGGGTCCAGATCACTGTGTGAAGTGTTTGCATCTGAAAGATGGACCCAACTGTGTGGAGAAGTGCCCTGATGGTCTGCAGGGAGCAAACAGCTTCATCTTCAAATATGCTGAGACCAACAACGAGTGCCATCCCTGCCACCCCAACTGCACCCAGGGTTGTACTGGACCCCGAGTACAAGATTGTGTTGGCATGTTGGACAGGACTCCTCTGATTGCGGCTGGGTTAATCGGGGCTCTCTTTGTGATGGTCATCATAGCTCTTGGTGTGGCTGTTTACATCCGCAGAAAGAGCATTAAGAAGAAGAGAGCTTTACGTCGTTTCCTGGAGACTGAGTTGGTGGAGCCGTTGACGCCCAGTGGTACAGCACCAAACCAGGCTCAGCTGCGGATACTGAAGGAAACTGAGCTCAAGAGGGTCAAGATTCTGGGAAGTGGAGCCTTTGGCATGGTCTATAAGGGAATCTGGGTTCCAGAAGGAGAAACAGTGAAGATTCCAGTGGCTATAAAGATACTCAATGAAAGTACAGGACCTAAAGCCAATGTGGAGTTTATGGATGAGGCGCTGATCATGGCCAGCATGGAGCATCCTCATCTAGTGCGTCTGTTGGGGGTCTGCTTGAGTCCCACTCTTCAGCTGGTAACTCAGCTCATGCCCCACGGCTGTCTGCTGGACTATGTTCATGAGCACCAGGAGAACATCGGCTCCCAGCTGCTGCTCAACTGGTGCGTGCAGATCGCAAAGGGTATGATGTACCTGGAGGAGAGGCGGCTGGTGCACAGGGACCTCGCGGCTCGTAACGTCCTGGTAAAATCTCCAAACCACATTAAGATCACTGATTTTGGACTTGCTCGACTGCTTGATGCCAATGAAAAGGAGTATAATTCAGATGGAGGCAAGATGCCCATCAAGTGGATGGCTTTAGAGTGCATACATTACAGGAAGTTCACACACCAGAGTGATGTATGGAGTTATGGGGTGACTATCTGGGAGCTGATGACGTTTGGAGGAAAGCCCTACGATGGGATTTCCACACGTGACATTCCAGACATCCTGGAGAAGGGCGAGCGTTTGCCCCAGCCGCCCATCTGCACCATAGACGTCTACATGGTGATGGTGAAATGCTGGATGATTGATGCTGATAGTCGTCCTCGGTTTAAAGAACTCGCTGCAGAGTTCAGCCGCATGGCACGAGACCCTCAGAGATACCTCGTCATACAGGGGGACGATCACATGAAGCTGCCCAGCCCCAACCACAGTAAGTTCTTCCAGAGTCTTCTAGATGAGGAGGAGCTGGATGACCTGATGGACGCTGAGGAGTACCTGGTTCCTCAGACCTTCAATATCTCTACCTCTTCTTACACGTCAAGACCACCGATGGATACCAGTAGGGTTACTGGTAATCCAAACATTTATATCATTAATACAAGCCGATATGGAGTTGGTGGGAAAAGGTGTGAGTTGAAAAGGTGTGAGTTGGGTGTCATCTGCAAAGCAATGGAAGTTGAAGCCATGATGACGGATAATGTTATCAAATGGGAGCATGTAGATGATGAACAGTACAGGCCCAAGAACAGAACCCAGGGGAACACCACGCAGCTGAGGTGTCGTGACAGAAGCCCAGAAGGCGGGATGGGAGCTTGTTCCCATGACACTTCTGGTTCAGCGAGTGGCGTCTTCATCCCTGTAAGCACACAAGGTGCGGGTCTCGATGTTCTTGAGGAACAACACTGTAATGGGAGCTTGAAGAAACAGCCCATGTCTGGCTCAGGAGACGACTGCGACGGCCAGCGCTACAGTGCAGACCCGACTGTCTTTTTTGGAGAGAGGGGTCCAAAGACCACCGATGAAGATGGTTACATGAGCCCCATGAACAAGTCAGCCTCAGACCATCTTAGTCCTGTCGAGGAGAATCCTTTTGTAAACCAACGGAAAAATGGAAATATTAATGCACTGGACAACCCGGGTTACCACAGCACTCCTGATAGGAAACCCAAAGGTGAGGATGAGTACATCAACGAACCCCTTTACCTCAACACATACAACAACACTAGTGGGATGAACCAGGAGATTGTGAGAAAAAATGGAGCTTCCATCCCACTACAGATGACTACAGCAGCCAGCACCGCAAGCAGCCACGTTATCCTCTCCACACAAACTGGGAAAGCCCACCACCACGGCCAGGGAACACATGTTCATTTCGCCGTTCCACCTGTTCAGCCCCCCCAAACGAGATCAATGAGCCAAAATGGCCAGCATTCCCAGTCACCCCATGGTGTCGAATCCAATTCCTCCAGCATGTCTGGCAATCCTTCCTTATTAACCCAAATCTCCATCGTCAGCCAACAGATCCAACCTTGTCTGGCAAGTCAGTCCGGCTCTTCAACCCATCCGGCTCAAGTGGTGAAATCTGCAGTCACAAGTAAAAGCATATCCGGCCTTCCCGGCCACCTTGTATACCCAGGTAACATGCTTCAAACGGGTCATACTGGGACTGTAATGGTCGACAGGAAGTCGAAGAAGAATTTTGATAATCCTGACTACTGGCAGCATAGTCTACCGCCCAAGGTGACCCAACAAAACCCTCAAGACCCAACGCAAGTTTGCAAAAGCAAACACCTCTATAGGCACAGCATCCGAAGTCGCATCGCTGTGGCTGACAACCCTGAGTATCTTTCCGAGTTAAACAAGAGAGCGGTTCTGCCACCTCCACCATACCGGCACAGGAATACGGTGGTGTAACGTCACAGTCGTTATAGTTAGCCAGATTCTTCTACCAGCACCATACGTTAAACTGGAAGTACTGAAGTACAGGAAAACTCCCAACTTCAGTGTTTCTGCCAGAGGAATTCAGGAAGGAGACTTATTGGACTTTAAAAGGAAAACCGACCAACCAAAGTGCCTCGAAACTATTCCAAAAGCTATTCCATCTTTTATATTCCAACAAATCAGAATGTAACCAGATGAATATCCCTTAAAGGGATAATTCACCAAAAATTTAAATTGTCATCATTTACTTAACCTCGTGTTGCTCCAAACACAAAGGATGTTGGAGATTTCTATCCCTCCAAGTCCATTACACTTAAAAAATATATAAATAAATAATAAAATTTTGATTCAATATTAATCCAAAACATTCCTTTTCCTAAAGTCAAAAAATAACTTTCATACCAACTGAATCTGTTATTTATTATGAAGACCACTTAATGTATATATGAATCAAATTATTTTTAGACACAAGCCAAAATGTTACTTAAAGTAGGTTGACATAATATATATATATATATATATATATATATATATATATATATATTGCCTCTGTACAACTTAATTTTACCATAAACAAAAGCTTAATCACTAAAGATAAAACTAAAACATGTTAATGATTAATTTAGTTTTCTTGCTATAAATAAAGCAACTTTGAAAAACCTTAATGTCTATTGTAAAGTGTTTTTAAAATATGCATCATCTTTTCTGTTATGTACACAAAAAAAAACTAAAACACCTAAATAAATAAATAAATAATAATAATAAAACCCACAATAATGTATGTAGTCAGTAAATGTGTTCTGCACATCAACAACCTGGTGTCAAGCAAAAATACTATTTAAACAAAATTGTTTTGTTTTATTTTTTTCAATGGGAAGTGTTATTTGATTTTAGCTAAACCGAACAAAACCATGATTTTCGATTTGACCAATATAAAAAATGCACTTTAAATAAACTACACAGTCATTTCACTTTTTTCAGTGTATGCCAAAACTTCATAAGGAGTACATAAAATGTTCATAAAGACAGTAAA

Function


symbol description
erbb4 Enables several functions, including epidermal growth factor receptor binding activity; protein homodimerization activity; and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including positive regulation of phosphorylation; positive regulation of signal transduction; and protein phosphorylation. Located in basolateral plasma membrane; mitochondrion; and nucleus. Part of receptor complex. Implicated in amyotrophic lateral sclerosis type 19; colorectal cancer; esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Biomarker of carcinoma (multiple); ductal carcinoma in situ; reproductive organ cancer (multiple); and urinary bladder cancer.

GO: NA

KEGG:

id description
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4

RNA


RNA id representative length rna type GC content exon number start site end site
CI01000299_03594891_03678552.mRNA True 5433 mRNA 0.45 28 3594891 3679612

Neighbor


gene id symbol gene type direction distance location
CI01000299_03495286_03498691 NA coding upstream 96162 3494539 ~ 3498729 (+)
CI01000299_03478949_03486009 NA coding upstream 108882 3476088 ~ 3486009 (+)
CI01000299_03453437_03453736 NA coding upstream 140682 3452300 ~ 3454209 (+)
CI01000299_03382616_03423028 NA coding upstream 171194 3382491 ~ 3423697 (+)
CI01000299_03366963_03373293 NA coding upstream 221209 3366818 ~ 3373682 (+)
CI01000299_03981006_04059237 ERBB4 coding downstream 301394 3981006 ~ 4059237 (+)
CI01000299_04105476_04115171 LANCL1 coding downstream 425864 4105476 ~ 4115227 (+)
CI01000299_04122601_04126314 MLE3, MYLZ3, MYL1 coding downstream 442989 4122601 ~ 4126381 (+)
CI01000299_04131136_04133439 PCNP coding downstream 451448 4131060 ~ 4133941 (+)
CI01000299_04259743_04263032 ENG1B, EN1 coding downstream 579309 4258921 ~ 4263493 (+)
G405579 NA non-coding upstream 37788 3552314 ~ 3557103 (+)
G405575 NA non-coding upstream 59193 3505295 ~ 3535698 (+)
G405697 NA non-coding upstream 122276 3472375 ~ 3472615 (+)
G405695 NA non-coding upstream 125692 3468997 ~ 3469199 (+)
G405710 NA non-coding downstream 18816 3698428 ~ 3725180 (+)
G405742 NA non-coding downstream 98421 3778033 ~ 3783926 (+)
G405578 NA non-coding downstream 213408 3893020 ~ 3912958 (+)
G405569 NA non-coding downstream 385519 4065131 ~ 4065565 (+)
G405797 NA non-coding downstream 397193 4076805 ~ 4077037 (+)
G405609 NA other upstream 439717 3154597 ~ 3155174 (+)
G403972 NA other upstream 2988541 604870 ~ 606350 (+)
G403609 NA other upstream 3184103 364139 ~ 410788 (+)
G403578 NA other upstream 3522620 35462 ~ 72271 (+)
G405842 NA other downstream 615921 4295533 ~ 4320141 (+)
CI01000299_04480751_04492829 NA other downstream 810206 4480553 ~ 4493116 (+)
CI01000299_04703290_04704365 NA other downstream 1022770 4703071 ~ 4704780 (+)
G406096 NA other downstream 1244850 4924462 ~ 4927844 (+)

Expression



Co-expression Network