CI01000299_03981006_04059237 (ERBB4)



Basic Information


Item Value
gene id CI01000299_03981006_04059237
gene name ERBB4
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information


Item Value
chromosome id CI01000299
NCBI id null
chromosome length 6567443
location 3981006 ~ 4059237 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence


>CI01000299_03981006_04059237.mRNA
TGTCCTGGCACTGATAACAAGCTCAGCACGCTGTCTGATTTGGACCAGCAGTACAGAACTCTCCGCCAGTTCTACGAGAACTGTGAGGTGGTCATGGGTAATCTGGAGATCACCAGTATTGAACGAAACCGCAACCTGTCTTTCCTCAAGTCTATCCGTGAGGTGACGGGTTATGTGTTGGTGGCTCTGAACCAGTTCGAATATCTTCCTCTGGAGAACCTGCGGATCATCCGTGGCACTAAACTGTACGAAGGACGCTACGCGCTGTCCATCTTTCTCAACTACAGACGAGATGGACACTTCGGCCTTAGACAACTCGGCCTCAAGAACCTGACAGAAATCCTGAATGGAGGCGTGTATGTGGATCAGAACAAGTTCTTGTGCCACGCTGACACCATCCACTGGCAAGACATCATCAAGAACCCTCGTTCTGAGCTTCTGGTTGTGCCCTCAAACAACAGTGGCAGCACATGTGAAAGGTGTCATCGCTCCTGTAACGGCCGCTGCTGGGGCCCGCAGGAGGATCAGTGCCAAAGCTTGACAAAGACGGTGTGTGCAGAGCAGTGTGATGGACGGTGTTTTGGTCCGTACGTCAGTAACTGCTGCCACCGTGAATGTGCAGGAGGCTGTTTCGGACCCAAAGACACGGACTGCTTTGCTTGTACCAACTTTAATGACAGCGGGGCCTGTGTGACACAATGTCCTCAGCCATTCGTCTACAATCCAACAACCTTTCAGCTCGAGCACAATCCCAATGCCAAATACACCTATGGAGCGTTCTGTGTCAAGAAATGCCCACATAACTTTGTGGTGGATCACAGCTCTTGTGTCAGAGCCTGTCCGAGCAACAAGATGGAGGTGGAGGAAAACAACATCAAGATGTGCATCCCGTGCACTGACATCTGTCCGAAAATGTGTGATGGTATAGGTACCGGCAGTCTTCAAACGGCTCAAACTGTAGATTCCAGCAACATTGAGAAGTTTGTCAATTGCACCAAAATCAACGGCAACCTCATCTTCCTCATCACGGGCATCAAAGGAGACGCGTATCATGATATCAGAGCTCTGGATCCCGAGCGACTAAATGTGTTCCGCACCGTCAGAGAGATCACAGGTTACTTGAACATCCAGTCTTGGCCAGAAAACATGACTGACCTTGGTGTCTTTTCCAACCTTGTCACCATAGGAGGAAGAACCCTTTATAGTGGTATTTCTCTGCTGATCCTGAAGCAGCGCTGGATCTCTTCACTGCAGTTCCAGTCTTTGAGAGAGATCAGCGCCGGTAACGTCTACATGACCAACAACAGCCAGCTCTGCTTCTACAATACAGTGAACTGGACCGGTCTGTTCCGCACCAGCACCCAGAGAGCTGTGATCAAGAACAACAGGGACCCCAGAGAGTGTACCAAACAGAAGATGGTTTGTGATTCACTATGTTCAGCGGCAGGATGCTGGGGTCCCGGTCCAGATCAATGTCTCTCTTGTAAATACTTAAGTCGGGGAAGAACATGTGTGAAATCCTGTAATCTTTATGATGGAGATGTTCGAGAGTTTGCCAATGGATCTGTGTGTGTGGAATGTGACAGCCAGTGTGAAAAGGCTGAAGATAAAACTCTTACCTGTCATGGGCCTGGTCCAGATCACTGCGTGAAGTGCTTGCATCTGAAAGATGGACCCAACTGTGTGGAGAAGTGCCCTGATGGTCTGCAGGGAGCAAACAGCTTCATCTTCAAATATGCTGAGACCAACAACGAGTGCCATCCCTGCCACCCCAACTGCACCCAGGGGTGTACTGGACCCCGGATTCAAGATTGTATTGGGATGCTGGACAGGACTCCTCTGATTGCAGCTGGGGTGATTGGGGGGATGTTTGTGGTTGTGATCGTGGCGCTCGGATTTGCTATCTTTTTCCGTCGGAAGAGCATCAAGAAGAAAAGAGCTTTACGCCGTTTCTTAGAAACAGAGCTGGTAGAGCCTTTAACGCCGAGCGGCACGGCACCCAACCAGGCACAGTTACGTATACTGAAGGAGACGGAGCTCAAGAGGGTCAAGATCTTGGGAACAGGAGCCTTTGGCACTGTTTACAAGGGAATCTGGATTCCAGAAGGAGAAACAGTGAAGATTCCTGTGGCCATAAAGATCCTCAATGAAAGTACAGGACCTAAAGCCAATGTGGAGTTTATGGATGAGGCGCTGATCATGGCCAGCATGGAGCATCCTCATCTAGTGCGTCTGTTGGGGGTCTGCTTGAGTCCCACTCTTCAGCTGGTAACTCAGCTCATGCCCCACGGCTGTCTGCTGGACTATGTTCATGAGCACCAGGAGAACATCGGCTCCCAGCTGCTGCTCAACTGGTGCGTGCAGATCGCAAAGGGTATGATGTACCTGGAGGAGAGGCGGCTGGTGCACAGGGACCTCGCGGCTCGTAACGTCCTGGTAAAATCTCCAAACCACATCAAAATCACTGATTTTGGACTTGCTCGACTGCTGGAAATAGATGAAAAGGAGTACAGCGCGGACGGAGGCAAGATGCCCATCAAGTGGATGGCCCTGGAGTGCATTCACTACAGGAAGTTCACACACCAGAGCGATATATGGAGCTATGGGGTGACTATCTGGGAGCTGATGACGTTTGGAGGAAAGCCCTACGATGGGATTCCCACACGTGAGATCCCAGACATCCTGGAGAAGGGCGAGCGTTTGCCCCAGCCGCCCATCTGCACCATAGACGTCTACATGGTGATGGTGAAATGCTGGATGATTGATGCTGATAGTCGGCCTCGGTTTAAAGAACTCGCTGCAGAGTTCAGCCGCATGGCACGAGACCCTCAGAGATACCTCGTCATACAGGGAGATGATCGCATGAAGCTGCCCAGCCCCAACCACAGTAAGTTCTTCCAGAGTCTTCTAGATGAGGAGGAGCTGGATGACCTGATGGACGCTGAGGAGTACCTGGTTCCTCATTCCTTGAATGCTCCTCCCACTTCCCACATGCCCCACCCACATGTAGATTCAAATCAAAACCAGTTTGGGTATCATGATGGAAGTTTGTGCCCTGAAGAGGTAACAGGGTCCCGACCTCATGAGGCAGTTGCTACAGGAAGTGTCCCGGCAGGACTCATACAAAGAGCCGGTCTGGACCCAGCAGAGGATCCGCACTGTAACGGAAATTTGAAGAAACAGGCCACAGCTCACTCAGCAGAGGACAGTAGTGGTCAGCGCTACAGTGCAGACCCGACCGTCCTCTTGGGAGAGAAAGGACAGAGGGATGATACAGATGAAGATGGTTATATGTCCCCTATGAAGGACAAGATCTCCACAAATCATCTAAATCCCGTTGAGGAGAATCCTTTTGTAACAAGGCGTAGAAATAAAGACGTTCACGCGCTAGACAACCCAGGTTACCACAGCACCCCTGATGGAAAGCCCAAGTGTGAAGATGAATACATCAATGAGCCCCTTTACCTCAACGCATTCAACAACACCAGCGACATGAACCAGGAAATGTTAAGGAAAAATGGAGTCTCCATCCCATTGCAGGTGACCACAGCCGCCCACACTCCAGGCACCCACGTTCCCCACATCACACAACTGGGCAAACCCCATCATCACAGCCACGGACCGCACGTTCACTTCGCCATACCACCAGTTCAGCTGGTTCACCCTGTACCGATGAGCCAAAATGATCAACATATCCATTCGGTTCAGTCGGTTCATGATCACGGCAGCAAATCTGGCTCGCAAGCACCAGTAGGCCAGATCTGTCTTGTGAGCCATCAAGTCCAACCAGGACACCCAAGCCAATCGAATCGTTCCCCACAACAGTTTCATTTGGCAAAGTCCACAGTGGTAGGTAAGCTACCGGGTCACCCGGTGCAACCAGGCAGCCAGATTGGGACCACATTAGTGGACAAGATGTACAAGAATAGCTTTGACAATCCTGAGTATTGGCAGCACAGCCTTCCACCCAAGGAGAACTCCCAAGACTCTTCGGTGGTCTGCAATAACAAGTTCCTTCACAAGCAGAACGGCCGCATACAGCCTGCCGTGGCTGAAAACCCTGAATATCTGTCTGGAATGAAGCCAGGAACAGTCCTGCCTCCTCCTCCGTACCGACAGAGGAACACTGTGGTC

Function


symbol description
erbb4 Enables several functions, including epidermal growth factor receptor binding activity; protein homodimerization activity; and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including positive regulation of phosphorylation; positive regulation of signal transduction; and protein phosphorylation. Located in basolateral plasma membrane; mitochondrion; and nucleus. Part of receptor complex. Implicated in amyotrophic lateral sclerosis type 19; colorectal cancer; esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Biomarker of carcinoma (multiple); ductal carcinoma in situ; reproductive organ cancer (multiple); and urinary bladder cancer.

NR:

description
Receptor tyrosine-protein kinase erbB-4

GO: NA

KEGG:

id description
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4

RNA


RNA id representative length rna type GC content exon number start site end site
CI01000299_03981006_04059237.mRNA True 4134 mRNA 0.51 26 3981006 4059237

Neighbor


gene id symbol gene type direction distance location
CI01000299_03594891_03678552 ERBB4 coding upstream 301394 3594891 ~ 3679612 (+)
CI01000299_03495286_03498691 NA coding upstream 482277 3494539 ~ 3498729 (+)
CI01000299_03478949_03486009 NA coding upstream 494997 3476088 ~ 3486009 (+)
CI01000299_03453437_03453736 NA coding upstream 526797 3452300 ~ 3454209 (+)
CI01000299_03382616_03423028 NA coding upstream 557309 3382491 ~ 3423697 (+)
CI01000299_04105476_04115171 LANCL1 coding downstream 46239 4105476 ~ 4115227 (+)
CI01000299_04122601_04126314 MLE3, MYLZ3, MYL1 coding downstream 63364 4122601 ~ 4126381 (+)
CI01000299_04131136_04133439 PCNP coding downstream 71823 4131060 ~ 4133941 (+)
CI01000299_04259743_04263032 ENG1B, EN1 coding downstream 199684 4258921 ~ 4263493 (+)
CI01000299_04269257_04269673 NA coding downstream 209230 4268467 ~ 4269765 (+)
G405578 NA non-coding upstream 68048 3893020 ~ 3912958 (+)
G405742 NA non-coding upstream 197080 3778033 ~ 3783926 (+)
G405710 NA non-coding upstream 255826 3698428 ~ 3725180 (+)
G405579 NA non-coding upstream 423903 3552314 ~ 3557103 (+)
G405575 NA non-coding upstream 445308 3505295 ~ 3535698 (+)
G405569 NA non-coding downstream 5894 4065131 ~ 4065565 (+)
G405797 NA non-coding downstream 17568 4076805 ~ 4077037 (+)
G405568 NA non-coding downstream 19738 4078975 ~ 4116184 (+)
G405573 NA non-coding downstream 69757 4128994 ~ 4129600 (+)
G405577 NA non-coding downstream 120613 4179850 ~ 4196335 (+)
G405609 NA other upstream 825832 3154597 ~ 3155174 (+)
G403972 NA other upstream 3374656 604870 ~ 606350 (+)
G403609 NA other upstream 3570218 364139 ~ 410788 (+)
G403578 NA other upstream 3908735 35462 ~ 72271 (+)
G405842 NA other downstream 236296 4295533 ~ 4320141 (+)
CI01000299_04480751_04492829 NA other downstream 430581 4480553 ~ 4493116 (+)
CI01000299_04703290_04704365 NA other downstream 643145 4703071 ~ 4704780 (+)
G406096 NA other downstream 865225 4924462 ~ 4927844 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location