XLOC_012775 (agk)


Basic Information

Item Value
gene id XLOC_012775
gene name agk
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 20532618 ~ 20540709 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00025491
TGCACCGGTCATGCTTTGGGAGATCAATGGAATGTCAACGGTGAAGAGCTCTATTCAGTCTTCTTGCTCATTTAGACATGCAAATATCGGCTGTATAGAAAGCccgtatatataaaaataatggcTCGGGTGGTGAAAGTGTTCCGAACTTTAAGAAATCATTGGAAAAAGTCCACATTTGCGGTGTGTGTGCTCTCATATGGAGGACACTGGCTCTATGGAAATCACTGTGACAGTGTGCTGCGACGTGAAGCATGTATAGAGGCTAGGGCATTTGGTCAACAGTTAATTGGACCTCAGGAGATTCTGAAGAAAGCCACAGTCATTCTGAATCCTGCTGCCTGTAAAGGCAAGGCGAATCAGTTGTTTGAGAAGAATGCAGCTCCCATTTTACATCTGGCTGGTGTGGAAGTTAAAATTGTGAAGACTGATTATGAAGGCCAGGCAAAAAAGCTCATGGAACTGATGGAGCAAACGGATATGCTGATCATCGCTGGCGGTGATGGGACGTTACAGGAGGTGATAACCGGCCTGCTTCGTAGAGCTGATGAGGAGATCTTCAGTAAAACACCAATTGGTTTTATCCCTCTGGGTTCCAGTAACTCTCTGAGTCAGAGTCTGCATCTAGTCTCTGACAATAAAGTACAGCACATTACCTCAGCAACTCTTTCAATCTTAAAAGGAGAAACGGTTCCACTGGACGTACTGCAGATAAAGGGTGAGAAGGAGCAGCCAGTGTTTGCGCTGTTGGGATTACGTTGGGGTGCATTCAGAGATGTAGCAACTTCTATTAGCAAATATTGGTACCTTGGCCCCTTGAAGACGAGAGCAGCACATTGGTTTAGTAGCCTGAAGCAGTGGCCACAGGTTCATGTGGCTTCCCTATCCTATCTGGCTCCCGTACCTCGTCCACCTGACCTTCCAGATGAAATACCACAGCGACCCAACCTCCTCTACCGCATCTACCGCAGACTCCAGAACTACTGGAACCCTCCTTTAGAAGAGCCACCAAAAGAGCCTGAGCCAGAGCAATGGGAGAGCAAAGACGTTTCTACATTGGAGCTTACCGTTCTCACACACAACAAGAACCCAGTCAAGAGGCGTGTAGATGATTCAATGCTGATCAGTCTGGACCCAGAATCCCTCACAGCTGGTCAGTTCATCACTGAGGGGACTAATAAATCAGTGGATCCCATGGAGCCCATAGAAAATGCTGTACAGATAGAAGCCAGTGCTGCACGTCTTGAACTCCCAGAGGAGGGTGCTGGCTTTTACGACATTGACAATCAGGAATATGAGGCAATGTCTGTCGAAGTGCGACTGCTGCCAAGAAAACTGAGATTCTTTTGCAGTGCAGAGCGCAGAGAGCAACTTGCAGAAGCTCAGTGATGACATAAAAATGTGGATTCATTTTCCAAAAGTACAAGAGGGAAAAAACATATCAGCTACCCCAAAAAAAGAAGTCGTCTTCATTGCGTAACTTGACAACTTGTGTACTATGAACTTGAAAAAATGAGTTTACACGTAAtgagttctgtcatcatttactcacactcatgttgttccaaacataTAAGAAATGTAGTTATCTtcaaaaatgaagatatttgtTTCTGCATCGAGTCTGTTCACCCAAAACTTGAACATATTTGATTATGGCCAGAGAGATtccaagttttaaaataaaatctaatgtgCGCTAAAGAGACATGATCACTTTATTAGATTACCCTTAAATTTAGggtttcattaaaacaagcatcGAGCTATAaacaaacatctttaaaacatttaaatttgatCACAGAAGCTCAGTGATGCTTGCTTGACATATGAGAACCACTGAGATTCATTTTTCACACCAACACGTTTAGCTTCTTTTTTTACTGATGCCTACATGTgaataaaataactgtatttattttgggggaaataaaaaatgtaaaatgtttaaagttgAACAAAAgtctttggaatgacatgaggagaTATGAGacatataatgaaataaattttaatttggaAAGATAGTTGAATGCGCTTATAAACATGTTATAAATGGTGTCAACTTAGTATGGAACAggttgttttcctgttttgaactTTTCTTACAAACTCTGGTTTACTTTAAGTGAATGTTTTCCTCAAAGAGCTTAATATTACCTTGAAGAGTGCAAAAATGCCTTTAGAAGAGATTTCTcactaaaaaaaggaaaatatactgACAATTTACTTACTTTCAAGTGGGTTAAAAGTGTTActttttctgttggacacaaaagaagatacttcaaAGAATGTTGGAAGCTGGTAGTCATTTCTTGTGTGTTAACAAAAAAGAGAGAAACTCAGATTTGGCTGAGAAAATGATGTCAGAAtatttgtttttgggtgaactgcccctttaagaaaCTCAAACTAGTTATGCTGTAAAAGTTTGACCAGATGAGGACCAATAATAAAAGTCATtatcatgcttt

Function

symbol description
agk Predicted to enable acylglycerol kinase activity; ceramide kinase activity; and diacylglycerol kinase activity. Predicted to be involved in ceramide biosynthetic process; phosphorylation; and protein insertion into mitochondrial inner membrane. Predicted to be located in mitochondrial inner membrane and mitochondrial intermembrane space. Predicted to be integral component of mitochondrial inner membrane. Predicted to be part of TIM22 mitochondrial import inner membrane insertion complex. Predicted to be active in membrane and mitochondrion. Human ortholog(s) of this gene implicated in Sengers syndrome and cataract 38. Orthologous to human AGK (acylglycerol kinase).

GO:

id name namespace
GO:0046512 sphingosine biosynthetic process biological_process
GO:0046513 ceramide biosynthetic process biological_process
GO:0006665 sphingolipid metabolic process biological_process
GO:0016310 phosphorylation biological_process
GO:0045039 protein insertion into mitochondrial inner membrane biological_process
GO:0046486 glycerolipid metabolic process biological_process
GO:0005743 mitochondrial inner membrane cellular_component
GO:0005758 mitochondrial intermembrane space cellular_component
GO:0042721 TIM22 mitochondrial import inner membrane insertion complex cellular_component
GO:0031305 integral component of mitochondrial inner membrane cellular_component
GO:0016020 membrane cellular_component
GO:0043231 intracellular membrane-bounded organelle cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0001727 lipid kinase activity molecular_function
GO:0001729 ceramide kinase activity molecular_function
GO:0047620 acylglycerol kinase activity molecular_function
GO:0017050 D-erythro-sphingosine kinase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0003951 NAD+ kinase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016301 kinase activity molecular_function
GO:0004143 diacylglycerol kinase activity molecular_function

KEGG:

id description
ko00561 Glycerolipid metabolism

ZFIN:

id description
ZDB-GENE-030131-6202 Predicted to enable acylglycerol kinase activity; ceramide kinase activity; and diacylglycerol kinase activity. Predicted to be involved in ceramide biosynthetic process; phosphorylation; and protein insertion into mitochondrial inner membrane. Predicted to be located in mitochondrial inner membrane and mitochondrial intermembrane space. Predicted to be integral component of mitochondrial inner membrane. Predicted to be part of TIM22 mitochondrial import inner membrane insertion complex. Predicted to be active in membrane and mitochondrion. Human ortholog(s) of this gene implicated in Sengers syndrome and cataract 38. Orthologous to human AGK (acylglycerol kinase).

Ensembl:

ensembl_id ENSDARG00000009837

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00025491 True 2480 mRNA 0.40 15 20532618 20540709

Neighbor

gene id symbol gene type direction distance location
XLOC_012774 rapsn coding upstream 21603 20494413 ~ 20511015 (+)
XLOC_012773 ddb2 coding upstream 40559 20468157 ~ 20492059 (+)
XLOC_012772 NA coding upstream 155683 20328119 ~ 20376935 (+)
XLOC_012771 NA coding upstream 207397 20316443 ~ 20325221 (+)
XLOC_012770 tle3a coding upstream 275107 20225961 ~ 20257511 (+)
XLOC_012776 wee2 coding downstream 19733 20560442 ~ 20565982 (+)
XLOC_012777 bida coding downstream 26108 20566817 ~ 20573129 (+)
XLOC_012778 cftr coding downstream 136381 20677090 ~ 20722810 (+)
XLOC_012779 ttc23 coding downstream 284666 20825375 ~ 20853748 (+)
XLOC_012780 pgpep1l coding downstream 329214 20869923 ~ 20875997 (+)
XLOC_012769 BX890624.2 non-coding upstream 324489 20089381 ~ 20208129 (+)
XLOC_012759 NA non-coding upstream 911665 19524841 ~ 19620953 (+)
XLOC_012756 NA non-coding upstream 1116578 19413097 ~ 19416040 (+)
XLOC_012781 BX548061.1 non-coding downstream 480990 21021699 ~ 21023601 (+)
XLOC_012786 NA non-coding downstream 622715 21163424 ~ 21169748 (+)
XLOC_012787 BX571884.1 non-coding downstream 650956 21191665 ~ 21191784 (+)
XLOC_012790 NA non-coding downstream 928927 21469636 ~ 21473364 (+)
XLOC_012792 CT573204.1 non-coding downstream 1537435 22078144 ~ 22081753 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000013_03897674_03902314 AGK coding CI01000013 null 3896594 ~ 3902314 (-)