XLOC_012969 (lmo2)


Basic Information

Item Value
gene id XLOC_012969
gene name lmo2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 38288877 ~ 38296665 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00025823
TCATTGTCGAGCCGTCGTGAGCAGGAAGTCGGAAAAGAGCAGAAACTGAGGGGGCAGGGCCATTTAAAAATACCTGCTGCCCTACAATAACGGGACACAGAGACAGCAGCCCTGCGGGACACTGGCGTGGCGACTTGCAGCGCAAAATGCACCACAAACAAGACGGAGCCTAAACGCCACATTTATCACGCGCCGGAGAAATTGAACAACGCCACTGTCTGTCACCTCACATTATTCAGACAGAACATAGGACTGAATGCGTGGTGACAGAAATCTAATGTAAATGAAGGATGCTTGGAATCTGGCGTACACAATGTGTGCTGGATGTTTCTGACCTTTGATACACTTGCTAAGACAGCAGAACAGGTGCATCTCTGAAGCGTTTTGTGCGGCAGATGGTCTTTCGGAACCGCAGAGGGCGAGTACGGGACATATTTGGCTTAAAAGGCGTGCATACCAAATGTGCTGAATTATACCTGAATCATATTGAAAATGGCTTCTACAATTGAACGGAAAACACTGGAGGCAAATGAGGAGCCGGTGGATGAGGTGCTCCAGATGCCGCCGTCACTGCTGACCTGTGGCGGGTGTCAGCAGAGCATCGGAGACCGCTTCTTTCTGAAGGCCATCGAGCAGTACTGGCACGAGGACTGTCTGAGCTGTGACCTCTGCGGCTGCCGCTTAGGGGAGGTGGGACGCAGGCTTTACTACAAACTCGGCAGAAAGCTGTGCAGGAGAGATTACCTCAGACTGTTTGGTCAGGACGGACTCTGTGCTTCCTGTGAAAAGAGGATCCGGGCCTTTGAAATGACCATGCGTGTGCGTGACAAAGTCTATCACCTCGAATGCTTCAAATGTGCTGCCTGTCAGAAACACTTCTGTGTTGGAGATCGTTACCTGCTCATCAACTCGGACATTGTGTGTGAGCAGGACATTTTTGAGTGGACCAAACTCAACGGCAGCATAGTATAGTTTTCTGCCGAAATCATAAACAAAATGTAACCTGTCAGCATTTTCAACAAACCCTTTACTAATAGAACatcaataacaaaatatatattttaaagaaatgatCTTTCTGGCTCTATTAGCTGTGCTCTAAATGCTTGtctctttttgttatttaaacttgAGAAAAATGCCACcaggtttcccagtgttgggttgcagctggaagggcatccactgcgtaaaacatatgctggataagttggcggttcatcccgctgtggcgacccctgatttttaaagggactaagccgaaaagaaaatgaataaatgaatgataattgcCACCAGCAACATGAACCTTTTttaaatttgatgtatttttgcaGAACAGCGTTATACAATTTTTAATGTATTGCAATAAAAACTGATTCCCTTTGCTACTTTTACACAATTACTTCGATTTGAACTATAGTTCTATTTGTTTTGAAGTAACACAATTGCAATAAAATGTACAGACATCTTAGAAAGATGATGCTTATTTTCTCAAGCTGCATTTTGTTCACTGGACAACTGTTTTctgtcaatttttaaaaatgtattttatttttgtgatgcAAGGCTGCATTTTCAGCAGTCTTCAATCCCATCTTCAGTGTCATATTAGCTTTAATTGgagctcaagaaacattttttcacattattttttattgtgtgaTGCTTTTTTGTGATGTGATATCTATAATATGTTATCAAAGTGCCAACAGAGCACACCCAATATTCCTAAAAGGACATAttgtatacatttcatatatattgtGTACATATtgtatgccaaaaaaaaaaaaaaaaaaaaa

Function

symbol description
lmo2 Predicted to enable metal ion binding activity. Predicted to contribute to DNA binding activity. Involved in hemopoiesis. Acts upstream of or within several processes, including fin regeneration; hemopoiesis; and retinal blood vessel morphogenesis. Predicted to be located in nucleus. Predicted to be part of protein-containing complex. Is expressed in several structures, including angioblastic mesenchymal cell; hematopoietic system; mesoderm; pronephros; and vasculature. Orthologous to human LMO2 (LIM domain only 2).

GO:

id name namespace
GO:0007275 multicellular organism development biological_process
GO:0048821 erythrocyte development biological_process
GO:0030218 erythrocyte differentiation biological_process
GO:0001568 blood vessel development biological_process
GO:0031101 fin regeneration biological_process
GO:0061304 retinal blood vessel morphogenesis biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0001935 endothelial cell proliferation biological_process
GO:0043534 blood vessel endothelial cell migration biological_process
GO:0032991 protein-containing complex cellular_component
GO:0005634 nucleus cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003677 DNA binding molecular_function

KEGG:

id description
ko05202 Transcriptional misregulation in cancer
ko04990 Domain-containing proteins not elsewhere classified

ZFIN:

id description
ZDB-GENE-980526-419 Predicted to enable metal ion binding activity. Predicted to contribute to DNA binding activity. Involved in hemopoiesis. Acts upstream of or within several processes, including fin regeneration; hemopoiesis; and retinal blood vessel morphogenesis. Predicted to be located in nucleus. Predicted to be part of protein-containing complex. Is expressed in several structures, including angioblastic mesenchymal cell; hematopoietic system; mesoderm; pronephros; and vasculature. Orthologous to human LMO2 (LIM domain only 2).

Ensembl:

ensembl_id ENSDARG00000095019

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00025823 True 1805 mRNA 0.42 3 38288877 38296665

Neighbor

gene id symbol gene type direction distance location
XLOC_012968 nucb2b coding upstream 78785 38191346 ~ 38210092 (+)
XLOC_012967 CR381582.2 coding upstream 270859 38017901 ~ 38018018 (+)
XLOC_012966 CR381582.1 coding upstream 325980 37962778 ~ 37962897 (+)
XLOC_012965 AL627088.2 coding upstream 830315 37458446 ~ 37458562 (+)
XLOC_012964 NA coding upstream 925849 37358896 ~ 37363028 (+)
XLOC_012970 alx4b coding downstream 24374 38321039 ~ 38364462 (+)
XLOC_012971 NA coding downstream 106660 38403325 ~ 38518803 (+)
XLOC_012972 NA coding downstream 451948 38748613 ~ 38754692 (+)
XLOC_012973 onecut1 coding downstream 458358 38755023 ~ 38760271 (+)
XLOC_012974 fam214a coding downstream 477919 38774584 ~ 38857612 (+)
XLOC_012963 NA non-coding upstream 1007711 37272515 ~ 37281166 (+)
XLOC_012980 NA non-coding downstream 868698 39165363 ~ 39173192 (+)
XLOC_012984 NA non-coding downstream 1324800 39621465 ~ 39632025 (+)
XLOC_012986 FO905036.1 non-coding downstream 1439724 39736389 ~ 39736503 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000180_01725004_01728058 LMO2, RBTN2 coding CI01000180 null 1725004 ~ 1728165 (-)
bowfin (Amia calva) AMCG00007265 lmo2 coding CM030123.1 CM030123.1 9522434 ~ 9526650 (+)