XLOC_015777 (acvr1l)


Basic Information

Item Value
gene id XLOC_015777
gene name acvr1l
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 41524238 ~ 41543762 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00031379
GGCGCAGTCTTTTCAGTCTCTCTGGGTGGCGGCAGACAGTCTGTCAGCGCTGAAAACACGACTTCGAATAAAAGAGTGATATTACGGAAATTGAACACAAACATGAATCTGCATTGCAGCTAAAGTGCATTGAACCAAATGGGGCATTGCAGCACCCAAATCATCATCCTGTTCCTGCTTCAGTTCTTACAGACATCAGCTAAAGATGTCTCCATTGACTGCATGTGTGTCGGCAGTGACTGTAATGAGCAGCAGTGTACTGGTGACCAGTGTTACACCTCCGTTATCATTAGCAATGATGTGACGACGTTCAAGCGGGGCTGCTTGATCGGGCCGGCGAGCAAGCGCATGACCTGCTCCGCAACAGCTTCTGCTAGTCATGTGGTAGAATGCTGTTCTCAACACATGTGCAACGCCAACGTCTCCAAAGAGACCCTACTTCGACTGCTGCTCACAA
>TCONS_00031380
GGCGCAGTCTTTTCAGTCTCTCTGGGTGGCGGCAGACAGTCTGTCAGCGCTGAAAACACGACTTCGAATAAAAGAGTGATATTACGGAAATTGAACACAAACATGAATCTGCATTGCAGCTAAAGGATCCAATGGGAAGACAGAGTCTGGCTGTGCGAATACTGAAAGGCAGTGCTGAGAGTCACTTGAGGAGTTGTACAATGCATTGAACCAAATGGGGCATTGCAGCACCCAAATCATCATCCTGTTCCTGCTTCAGTTCTTACAGACATCAGCTAAAGATGTCTCCATTGACTGCATGTGTGTCGGCAGTGACTGTAATGAGCAGCAGTGTACTGGTGACCAGTGTTACACCTCCGTTATCATTAGCAATGATGTGACGACGTTCAAGCGGGGCTGCTTGATCGGGCCGGCGAGCAAGCGCATGACCTGCTCCGCAACAGCTTCTGCTAGTCATGTGGTAGAATGCTGTTCTCAACACATGTGCAACGCCAACGTCTCCAAAGAGACCCTACTTCGACTGCTGCTCACAAGTCCAGAAGAAAAGAAGACTGTTCATTACCGCGTGGAAATGTTGGTTCTGTTTGTGTTGGGGCCGTTTGTGGTTCTGGGTCTGCTGTCTTTTCTGGCTTTGCTGGTGTGCCGTCGACTCCATCATGGGCGTCTGGAGAGACTGCACGAGTTTGACACTGAACAGGGGGCCATCGATGGGCTTATCGCGTCTAATGTCGGAGACAGCACACTTGCGGATCTGATGGATCACTCCTGCACTTCAGGCAGTGGTTCAGGACTGCCCTTCCTGGTTCAGAGAACGGTTGCGCGGCAGATCAGCCTGGTGGAGTGTGTTGGTAAAGGACGGTACGGTGAAGTGTGGAGAGGTCAATGGCAAGGAGAAAATGTAGCCGTGAAGATCTTTTCCTCTAGAGATGAGAAGTCATGGTTTCGAGAAACAGAAATTTACAACACTGTTCTGCTACGACATGAAAATATATTAGGCTTCATGGCTTCTGACATGACCTCCCGAAACTCTAGCACTCAGCTGTGGCTGATCACACACTATCACGAGAATGGCTCTCTGTATGACTACCTGCAGCGTGTGGCTGTGGAGATGGCAGATGGACTGCACATGGCGGCTTCGATTGCCAGCGGGCTGGTGCACCTGCACACGGAGATCTTTGGCACGGAGGGCAAACCGGCCATCGCTCACAGAGACCTGAAGAGCAAGAACATCCTTGTGAAGAAAGATTTGCAGTGCTGCATCGCTGACCTGGGTCTGGCAGTAACACACACGCAGTCTGATAATCAGCTTGATGTGGGAAATAATCCTAAAGTGGGAACCAAACGCTACATGGCACCGGAGGTTCTAGATGAGACCATTCAGACGGACTGTTTTGACGCCTATAAGAGGGTGGATATCTGGGCCTTTGGGTTGGTGCTGTGGGAGATCGCACGCAGAACCATCAGCAATGGAATTGTAGAGGAATACAAGCCGCCTTTCTATGACCTGGTTCCTAATGATCCCAGCTTTGACGACATGAGGAAAGTGGTTTGTGTGGAGCAGCAAAGGCCATTCATTCCCAACCGCTGGTTTTCAGATCCTACCCTGTCTGCTCTGGTGAAGCTGATGAAAGAGTGCTGGTACCAGAACCCCTCGGCTCGTCTCACTGCCCTGCGCATCAAAAAGACTCTGGATAAAATCCACAGTTCACTGGAGAAGGGCAAAACCGACTGCTGAGGAGAGAGAGAGCTGCAGAACTACTGACCGCTCACCCGCTCATTATACAGACACTGTGTGTAACCAAACCATTGGATTCCATCGCTGGCATCTGTCCCAACTCTAACATgctgtttatttgctttattcttCTTGTTCATTGGCCTAAAAACTTTTTTATAGAGAATTACGCTCTCTTTTATggattttatttttccccccgCTGAACCCGGTGGAACTCACATTTACCCTCAAGAAGCAACAAAAAGGACAGAGACGCCATCAAATATGTGGACGCACACTGACAGGCCTTGAAGAAACCCTCTGTCATGGATTTTTTTAACAGCATCACGTTGTCTATTTAACCATTGGCAGACTTTAAAGATTTGTACTTTTCAGAAAAATGAAAAGGACGGATACACACATGCTGAAATGCAATCAGtctcataatgtgtgtgtgtgcacatgattCTTGTTATAACCAGAAAAACTTCATAGCTGTAACATCACCTGCTTTTAGACATATGGTGGGTTTTGAGCTTTTTAAAGGTCCTGATAGTTCTTGTAGATAGGTTAGGCAAAGTTAGTCACAGTTTTGCTATAGTGGACTTATCATAAAACCGGTTGGTTGCTTAATGCCACTATGTACAGTAGGAATCAACAGGCTTCTTTCTTTAATTAGGCCTGTTTAGTGACCAGACCTGGGTTTTGAActagtggtaaaaaaaaaataaattctgtcatcatgtaattccaaaaataaataactttttcagtgggaaaaacacagaaaaagatgttttaaagaatgctcACGCTGCTCTTTTTCCATACAGTGAGCACATATTGTGGCATGCTCTCTAAAAATTAACGAAAACCGTTCATATAttgtttggaatgacatgaatgatgagtaaataatgagagaatcatttttttttaatatatatatttttttgtttgggtGAACTCGCAGTCTGGTCATTCTCATAGCACCCTATGAGGGCTTCCCTTTGACACAAGGCCTTTCTGACCTGTTGCCTCTATGCCTGCCTGACTAAAAGCCATTGTAGCACACCGTagtgcttttttgttttatttttttgtagctgTTGTCTTTATTTTTGCCCTCACAGGCATGCGTACTTGATGTTTGTTCAATGACAATCAGCCGCTGTCCAGTAGGGCCTGAACTATTTGCTGTCATGTACAAAACCCTACTTATGAGCTTTTAAGGTGACGTCTCAGCACACTAACAGAGCTAGTCATGATCATAAATAGACTCTGGTTTTGTGAATTTGCGTATTTGTTTACCCTCATGCTTTTTTCACACTTTTTGTATCACAGTTTTCAACACGCACCATGAGCCGAGAGAATTCGGAtgcttttaaaactttaaacgCTTTTTGACTATTTAAAAGTGACACTCTAATATAGGATGGAAGAGGTTTACAAAGGAAAATGCTATTGTTGTATACCGAATGGCTTGTGTATGTTGCTTATGGTTTGGGTTAAGTGAAattgtttgaatttaattttttttattttggaaaaattgGTCATGATACACTACAACTTTCACTTCTGGTCGCTTTTGCTCTCCTATAAAACCAAACGTTTACATGTTTGTGTTGACCTGGGGAGCGATGTTAGGAATTAAGACTACAGCAGCTATTGCATTATGAACTGTGAATGTTATAATGAAGAAACCTTATGTATGATGTTACTGGAATACTGAATGCGCGGTTAAGAATTAAAAGGAAATCTGCTTTTTTTCATCGGTTA
>TCONS_00031381
TCAGTCTCTCTGGGTGGCGGCAGACAGTCTGTCAGCGCTGAAAACACGACTTCGAATAAAAGAGTGATATTACGGAAATTGAACACAAACATGAATCTGCATTGCAGCTAAAGGATCCAATGGGAAGACAGAGTCTGGCTGTGCGAATACTGAAAGGCAGTGCTGAGAGTCACTTGAGGAGTTGTACAAGTAAGACTGTTAACTTTATTGTTTTTCGGATAAAATAATGCCACACATTTTCGAGAATTTAATCTACAATTAGTCATAGTGTCCTCCTGAGTTGTGTTCTTGAATTTTACACCACAATGGTGAGTTTGACACTCCCAAAATGTGTTTCTTTCTGCCTCTCCGAAAGTGCTCCTCTCCTTGTGTTTGATGTTGCTCCATAATGggcat
>TCONS_00031382
CTGAAAGGCAGTGCTGAGAGTCACTTGAGGAGTTGTACAATGCATTGAACCAAATGGGGCATTGCAGCACCCAAATCATCATCCTGTTCCTGCTTCAGTTCTTACAGACATCAGCTAAAGATGTCTCCATTGACTGCATGTGTGTCGGCAGTGACTGTAATGAGCAGCAGTGTACTGGTGACCAGTGTTACACCTCCGTTATCATTAGCAATGATGTGACGACGTTCAAGCGGGGCTGCTTGATCGGGCCGGCGAGCAAGCGCATGACCTGCTCCGCAACAGCTTCTGCTAGTCATGTGGTAGAATGCTGTTCTCAACACATGTGCAACGCCAACGTCTCCAAAGAGACCCTACTTCGACTGCTGCTCACAAGTCCAGAAGAAAAGAAGACTGTTCATTACCGCGTGGAAATGTTGGTTCTGTTTGTGTTGGGGCCGTTTGTGGTTCTGGGTCTGCTGTCTTTTCTGGCTTTGCTGGTGTGCCGTCGACTCCATCATGGGCGTCTGGAGAGACTGCACGAGTTTGACACTGAACAGGGGGCCATCGATGGGCTTATCGCGTCTAATGTCGGAGACAGCACACTTGCGGATCTGATGGATCACTCCTGCACTTCAGGCAGTGGTTCAGGACTGCCCTTCCTGGTTCAGAGAACGGTTGCGCGGCAGATCAGCCTGGTGGAGTGTGTTGGTAAAGGACGGTACGGTGAAGTGTGGAGAGGTCAATGGCAAGGAGAAAATGTAGCCGTGAAGATCTTTTCCTCTAGAGATGAGAAGTCATGGTTTCGAGAAACAGAAATTTACAACACTGTTCTGCTACGACATGAAAATATATTAGGCTTCATGGCTTCTGACATGACCTCCCGAAACTCTAGCACTCAGCTGTGGCTGATCACACACTATCACGAGAATGGCTCTCTGTATGACTACCTGCAGCGTGTGGCTGTGGAGATGGCAGATGGACTGCACATGGCGGCTTCGATTGCCAGCGGGCTGGTGCACCTGCACACGGAGATCTTTGGCACGGAGGGCAAACCGGCCATCGCTCACAGAGACCTGAAGAGCAAGAACATCCTTGTGAAGAAAGATTTGCAGTGCTGCATCGCTGACCTGGGTCTGGCAGTAACACACACGCAGTCTGATAATCAGCTTGATGTGGGAAATAATCCTAAAGTGGGAACCAAACGCTACATGGCACCGGAGGTTCTAGATGAGACCATTCAGACGGACTGTTTTGACGCCTATAAGAGGGTGGATATCTGGGCCTTTGGGTTGGTGCTGTGGGAGATCGCACGCAGAACCATCAGCAATGGAATTGTAGAGGAATACAAGCCGCCTTTCTATGACCTGGTTCCTAATGATCCCAGCTTTGACGACATGAGGAAAGTGGTTTGTGTGGAGCAGCAAAGGCCATTCATTCCCAACCGCTGGTTTTCAGATCCTACCCTGTCTGCTCTGGTGAAGCTGATGAAAGAGTGCTGGTACCAGAACCCCTCGGCTCGTCTCACTGCCCTGCGCATCAAAAAGACTCTGGATAAAATCCACAGTTCACTGGAGAAGGGCAAAACCGACTGCTGAGGAGAGAGAGAGCTGCAGAACTACTGACCGCTCACCCGCTCATTA

Function

symbol description
acvr1l Predicted to enable ATP binding activity; SMAD binding activity; and transforming growth factor beta receptor activity, type I. Acts upstream of or within several processes, including animal organ development; embryonic morphogenesis; and regionalization. Located in cell cortex. Part of BMP receptor complex. Is expressed in brain; ceratobranchial 5 tooth; immature eye; liver; and tooth placode. Human ortholog(s) of this gene implicated in fibrodysplasia ossificans progressiva. Orthologous to human ACVR1 (activin A receptor type 1).

GO:

id name namespace
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway biological_process
GO:0007179 transforming growth factor beta receptor signaling pathway biological_process
GO:0003342 proepicardium development biological_process
GO:0021556 central nervous system formation biological_process
GO:0007507 heart development biological_process
GO:0003140 determination of left/right asymmetry in lateral mesoderm biological_process
GO:0003143 embryonic heart tube morphogenesis biological_process
GO:0003146 heart jogging biological_process
GO:0046588 negative regulation of calcium-dependent cell-cell adhesion biological_process
GO:0071363 cellular response to growth factor stimulus biological_process
GO:0042476 odontogenesis biological_process
GO:0051216 cartilage development biological_process
GO:0035050 embryonic heart tube development biological_process
GO:0001525 angiogenesis biological_process
GO:0048264 determination of ventral identity biological_process
GO:0030509 BMP signaling pathway biological_process
GO:0030510 regulation of BMP signaling pathway biological_process
GO:0006468 protein phosphorylation biological_process
GO:0003230 cardiac atrium development biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0035124 embryonic caudal fin morphogenesis biological_process
GO:0048332 mesoderm morphogenesis biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0001889 liver development biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0048368 lateral mesoderm development biological_process
GO:0016310 phosphorylation biological_process
GO:0007420 brain development biological_process
GO:0060030 dorsal convergence biological_process
GO:0001944 vasculature development biological_process
GO:0001947 heart looping biological_process
GO:0035462 determination of left/right asymmetry in diencephalon biological_process
GO:0061371 determination of heart left/right asymmetry biological_process
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0005938 cell cortex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0070724 BMP receptor complex cellular_component
GO:0043235 receptor complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0046332 SMAD binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004675 transmembrane receptor protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0005025 transforming growth factor beta receptor activity, type I molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990415-9 Predicted to enable ATP binding activity; SMAD binding activity; and transforming growth factor beta receptor activity, type I. Acts upstream of or within several processes, including animal organ development; embryonic morphogenesis; and regionalization. Located in cell cortex. Part of BMP receptor complex. Is expressed in brain; ceratobranchial 5 tooth; immature eye; liver; and tooth placode. Human ortholog(s) of this gene implicated in fibrodysplasia ossificans progressiva. Orthologous to human ACVR1 (activin A receptor type 1).

Ensembl:

ensembl_id ENSDARG00000014986

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00031379 False 457 mRNA 0.49 3 41524238 41530598
TCONS_00031380 False 3499 mRNA 0.44 11 41524238 41543762
TCONS_00031381 False 396 lncRNA 0.42 2 41524250 41527150
TCONS_00031382 True 1619 mRNA 0.51 10 41526904 41542043

Neighbor

gene id symbol gene type direction distance location
XLOC_015776 NA coding upstream 275237 41230916 ~ 41249001 (+)
XLOC_015775 BX510333.1 coding upstream 488047 41036076 ~ 41036191 (+)
XLOC_015774 NA coding upstream 538933 40983293 ~ 40985305 (+)
XLOC_015773 NA coding upstream 752187 40770072 ~ 40772051 (+)
XLOC_015772 epha4b coding upstream 1010087 40294313 ~ 40514151 (+)
XLOC_015778 NA coding downstream 34306 41578068 ~ 41583029 (+)
XLOC_015779 NA coding downstream 227349 41771111 ~ 41795569 (+)
XLOC_015780 crlf1a coding downstream 332833 41876595 ~ 41920632 (+)
XLOC_015781 odf3l2a coding downstream 382945 41926707 ~ 41934019 (+)
XLOC_015782 gbp2 coding downstream 461455 42005217 ~ 42017282 (+)
XLOC_015771 NA non-coding upstream 1249726 40264625 ~ 40274512 (+)
XLOC_015783 NA non-coding downstream 469314 42013076 ~ 42013350 (+)
XLOC_015798 NA non-coding downstream 867126 42410888 ~ 42422644 (+)
XLOC_015799 BX005044.1 non-coding downstream 879922 42423684 ~ 42423799 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000190_00270401_00278872 ACVR1L, ACVR1 coding CI01000190 null 269858 ~ 278872 (-)