XLOC_018010 (ccm2)


Basic Information

Item Value
gene id XLOC_018010
gene name ccm2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 18774129 ~ 18794789 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035494
GCGGAATCATCACAGACAGTTTCGGCCGTTATAAGCGCACGACGAGCTCTGCGTCTGACTCCACCACGAACGGAAACGGTGCTGCGGGCGGATCAGATGAGGGAACAGCCACCTCTGAGGGCGACGAATGGGACCGCATGATTTCAGACATAAGCAATGACATTGAAGCCTTAGGAAGCAGCATGGATCAAGACGGCGTGCCATCTTGATGCCACGGCTCTCGGACTGcgactgtatttatttatttttgtttaccttTTATTTGGATTGGATGgtggaggacagacaggaaagcactgggagcagagagaggggaaggattggcataaGATCTTGGGCTggtatgaatgaatttaaaattattcaccccctttaaatttattttcttttttaaatattttccaaacgatGTTTTACAGAGtgaggaaatttttacagtatgtctgagaatatcttttcttctggagaaagtcttatttgttttatttcggctagaataaaagcagttagtaatttttttaaagaccattttaaggtctaaattattaacccttttaagcaatatatttttttcgattgtgtacagaacaaaccatcattatacctaattaacctagttaagcctttaaatgtcactttaagctgtatagaagtgtcttgaaaagaatttctagtcaaatattgtttactgtcatcatggtgaagataaaataaatcagt
>TCONS_00035495
ATCTAATACAGCGAAAATGAAGAGCATTTGTACGTAGAGATGGAGGAGGATGTAAAGAAAGTCAAAAAGCCAGGTATCGTGTCTCCGTTCAAGCGGGTGTTTCTGAAAGGGGAGAAGGGTAGGGATAAGAAGGCTCTGGAGAAGTCCACTGAACGCAGGGCCCTCCacaccttctctctctctctcccagacCACCGTATCGACCCAGATATTCTGCTCAATGACTACATCGAGAAGGAAGTTAAGtATCTGGGACAGCTGACCTCAGTTCCTGGATACCTGAATCCCTCCAGCCGCACTGAAGTTCTGCAGCTCATTGACAATGCCAGGAAGTCTCATCAGTTGGCTGGGCAGCTGACCTCAGAGCAGGATGCTGTTGTCAGTTTATCAGCGTACAATGTGAAGCTTGTGTGGCGTGATGGAGAGGACATCATTCTGCGCGTACCCATCCACGACATTGCAGCTGTGTCCTACATCAGAGACGACTCGCTTCATCTAGTGGTGCTAAAAACAGCTCAGGAGCCCGGAGGTTCCCCATGTCATAGTACAGAGATGTCGAAATCTCCCACTCTGAGCTCTCTATCTGAGAGTGGGGCTGTGCTGGTGGAGGTCTGCTGTCTGCTTGTGCTGGCTGTTGACAACAAGGCTGCAGCAGAGGAGCTCTGTCTTCTACTCAGTCAAGTCTTCCAGATCGTCTATACCGAGTCCACCATCGACTTCCTAGACAGGGCCATCTTTGATGGAGCCACAACACCCACCAGGCATCTCTCAATCTATAGTGAAGACTCCTCAAGTAAAGTTGATGTCAAAGATGTGTTTGAGGCCGAGGCAAGCACATTCTCGTTCCAGAGTTCTCTAGAGGCGGGACATTCCTCTAGCCCCTCCCCCACCTCGGCCCCGGCCTCGCCACAAACCAAAACAGCCAGTGAGAGCGAACTGAGCACAACAGCTGCTGAACTGCTGCAAGACTACATGACCACATTGAGGACAAAGCTTTCGTCCAAAGAGATCCAGCAGTTTGCCACACTGTTACATGAATACAGAAACGGCGCCTCCATCCATGAGTTCTGTATCAACCTGCGGCAGCTTTATGGAGACAGCAGGAAGTTCCTTCTCCTCGGACTGCGGCCGTTCATCCCCGAGAAGGACAGCCAGCATTTTGAGAACTTTCTGGAGACCATCGGCGTGAAGGATGGCCGCGGAATCATCACAGACAGTTTCGGCCGTTATAAGCGCACGACGAGCTCTGCGTCTGACTCCACCACGAACGGAAACGGTGCTGCGGGCGGATCAGATGAGGGAACAGCCACCTCTGAGGGCGACGAATGGGACCGCATGATTTCAGACATAAGCAATGACATTGAAGCCTTAGGAAGCAGCATGGATCAAGACGGCGTGCCATCTTGATGCCACGGCTCTCGGTGAGCTTTTGCCAATCGCCACACACAGGCCATCGGTCCGTATTGCTGTCTGTTTGAATCTGACAATGCTGGAGTTTGGATGCTGTATGGATGCCACTTCCTGACcgtcaattttatttttgtttgtcgtGCCATATTGTTGAGCGTTTTTAAAGAGCTGTGATGGAAGGATGTGTATTGCTGTGGACAGCAATCGTGTTCCTCTGGGATGTTTATTGGCAGTATCTGCTACCACTGAAGAGAAACCTTGTTGTTGGGTAGATGCGGCTCTTTCACACTGATCTGAGTTTGCTAGGTTCCCATTTAATAGCAAGTAGGGCTTGTGATATGTCGAAATAAAAATAGCAGTGTATACTTTCATCTATACTTTTCACTatctaataaacatttaaagccCTTTTACATAAGGATTATAACAATAATGTCAGATATGTTTTTAATATTGCTTTAAAGagtctacactca
>TCONS_00035496
ATGGAGACAGAGCCAGGTATCGTGTCTCCGTTCAAGCGGGTGTTTCTGAAAGGGGAGAAGGGTAGGGATAAGAAGGCTCTGGAGAAGTCCACTGAACGCAGGGCCCTCCacaccttctctctctctctcccagacCACCGTATCGACCCAGATATTCTGCTCAATGACTACATCGAGAAGGAAGTTAAGtATCTGGGACAGCTGACCTCAGTTCCTGGATACCTGAATCCCTCCAGCCGCACTGAAGTTCTGCAGCTCATTGACAATGCCAGGAAGTCTCATCAGTTGGCTGGGCAGCTGACCTCAGAGCAGGATGCTGTTGTCAGTTTATCAGCGTACAATGTGAAGCTTGTGTGGCGTGATGGAGAGGACATCATTCTGCGCGTACCCATCCACGACATTGCAGCTGTGTCCTACATCAGAGACGACTCGCTTCATCTAGTGGTGCTAAAAACAGCTCAGGAGCCCGGAGGTTCCCCATGTCATAGTACAGAGATGTCGAAATCTCCCACTCTGAGCTCTCTATCTGAGAGTGGGGCTGTGCTGGTGGAGGTCTGCTGTCTGCTTGTGCTGGCTGTTGACAACAAGGCTGCAGCAGAGGAGCTCTGTCTTCTACTCAGTCAAGTCTTCCAGATCGTCTATACCGAGTCCACCATCGACTTCCTAGACAGGGCCATCTTTGATGGAGCCACAACACCCACCAGGCATCTCTCAATCTATAGTGAAGACTCCTCAAGTAAAGTTGATGTCAAAGATGTGTTTGAGGCCGAGGCAAGCACATTCTCGTTCCAGAGTTCTCTAGAGGCGGGACATTCCTCTAGCCCCTCCCCCACCTCGGCCCCGGCCTCGCCACAAACCAAAACAGCCAGTGAGAGCGAACTGAGCACAACAGCTGCTGAACTGCTGCAAGACTACATGACCACATTGAGGACAAAGCTTTCGTCCAAAGAGATCCAGCAGTTTGCCACACTGTTACATGAATACAGAAACGGCGCCTCCATCCATGAGTTCTGTATCAACCTGCGGCAGCTTTATGGAGACAGCAGGAAGTTCCTTCTCCTCGGACTGCGGCCGTTCATCCCCGAGAAGGACAGCCAGCATTTTGAGAACTTTCTGGAGACCATCGGCGTGAAGGATGGCCGCGGAATCATCACAGACAGTTTCGGCCGTTATAAGCGCACGACGAGCTCTGCGTCTGACTCCACCACGAACGGAAACGGTGCTGCGGGCGGATCAGATGAGGGAACAGCCACCTCTGAGGGCGACGAATGGGACCGCATGATTTCAGACATAAGCAATGACATTGAAGCCTTAGGAAGCAGCATGGATCAAGACGGCGTGCCATCTTGA

Function

symbol description
ccm2 Acts upstream of or within several processes, including cell-cell junction assembly; circulatory system development; and heart contraction. Predicted to be located in cytoplasm. Is expressed in several structures, including cardinal system; heart; intermediate cell mass of mesoderm; liver; and ventricular zone. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 2. Orthologous to human CCM2 (CCM2 scaffold protein).

GO:

id name namespace
GO:0007507 heart development biological_process
GO:0007275 multicellular organism development biological_process
GO:0007043 cell-cell junction assembly biological_process
GO:0009948 anterior/posterior axis specification biological_process
GO:0001570 vasculogenesis biological_process
GO:0060047 heart contraction biological_process
GO:0005737 cytoplasm cellular_component

KEGG: NA

ZFIN:

id description
ZDB-GENE-040712-6 Acts upstream of or within several processes, including cell-cell junction assembly; circulatory system development; and heart contraction. Predicted to be located in cytoplasm. Is expressed in several structures, including cardinal system; heart; intermediate cell mass of mesoderm; liver; and ventricular zone. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 2. Orthologous to human CCM2 (CCM2 scaffold protein).

Ensembl:

ensembl_id ENSDARG00000013705

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035494 False 720 processed_transcript 0.38 2 18774129 18776493
TCONS_00035495 False 1886 mRNA 0.49 10 18775806 18794789
TCONS_00035496 True 1350 mRNA 0.53 10 18776285 18789543

Neighbor

gene id symbol gene type direction distance location
XLOC_018009 enpp5 coding downstream 37848 18721311 ~ 18736281 (-)
XLOC_018008 NA coding downstream 204710 18565758 ~ 18569419 (-)
XLOC_018007 NA coding downstream 223347 18548290 ~ 18550782 (-)
XLOC_018006 cdc42bpb coding downstream 237655 18391860 ~ 18536474 (-)
XLOC_018005 NA coding downstream 385510 18387859 ~ 18388619 (-)
XLOC_018011 xkr6b coding upstream 6736 18801525 ~ 18915376 (-)
XLOC_018012 BX510941.1 coding upstream 141666 18936455 ~ 18942965 (-)
XLOC_018013 BX510941.2 coding upstream 180201 18974990 ~ 19011956 (-)
XLOC_018014 NA coding upstream 375143 19169932 ~ 19174123 (-)
XLOC_018015 si:dkey-71h2.2 coding upstream 482143 19276932 ~ 19366022 (-)
XLOC_017928 CU539064.1 misc downstream 8720428 10053405 ~ 10053701 (-)
XLOC_018001 NA non-coding downstream 578811 18190516 ~ 18195318 (-)
XLOC_018000 NA non-coding downstream 754823 18016462 ~ 18019306 (-)
XLOC_018017 BX842692.1 non-coding upstream 587638 19382427 ~ 19385077 (-)
XLOC_018020 NA non-coding upstream 748354 19543143 ~ 19546588 (-)
XLOC_018021 dre-mir-206-1 non-coding upstream 749859 19544648 ~ 19544746 (-)

Expression


Co-expression Network