XLOC_018025 (ptk2bb)


Basic Information

Item Value
gene id XLOC_018025
gene name ptk2bb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 19827379 ~ 19864131 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035519
ATCTACCTGACTTTCAGAGCTGGACTTTGACTGGGGAACTTAAAGGAAATAGGAAAACATCAGGAGCACAGCTTTGCAAGATGAGATGACTGTGTAATGGTGTGTGGATTTCTTTGAGGACGTTTCTAGGACATGGCGAGTGATGCAAGCACCCTCTCCTGGAAGGTACCCGCTCAGGACTGGGATGGGGGCATCAAAAGCCCTGACCTGGGTCCTGTTGGAGATGGCGGCCCCGTGAAGATCATTAAAGTTTGCTTCAGTAGCAGCAACAACCTTAGCAAGAACTTCAAACTGGTCAAATGTGACAGCTCATGGCAGATCAAGACTATTATCCAGTCTATTCTGATCAGTGGGCGTTTGGGCCCGAATGTGCAGAACCCGGGCTGCTTTGGCCTGAGGCTCAAACACCTCAAATCTGAGGAGCTTCACTGGCTGCACCCAGACCTGACTGTAGGCGAGGTGGAGCAGCGCTATGAGAGCCATCACGCCGAGGCAGAGTGGAGGTATGACCTCAGAATCCGCTACATTCCCATTGATTATATGAAGAGGTTAAGAGAAGACAGAACGTTCCTGTTGTATTTCTATCAACAGGTGCGCAGTGACTACATGCAGCATCATGCTAGCAAAGTTAGTGACGGCATGGCTCTACAGTTGGGCTGTTTGGAAATCAGGAGATTTTATAAAGACATGAATGCCAAAGGTCTAGAGAAAAAGTCCAATTTTGACCTGCTCGAaaaagacgTTGGTCTTGACCTGTTCTTTCCCAAAGGACTCATTGACAGTATGAagCAAAGGCAGCTCAGAAAACTCATACAACAGACATTTCAGCAGTATGCCATACTAAAAGAGGATGACTGTATGGTTAAGTTCTTTGAGACCTATGGAGAGTTCTCCAACTTCGATGAGGAAATATTCCCTTGCGAGCTAGTGCAAGGTTGGAGTTTAGCAGTGGATTTAGTCATTGGTCCTAAAGGCATTCGTCAGAGAACCAAAGCAGACTCCACGGCTCTCTGCCTTGCTGAATACAAACAAATCCGAAGTATCAAGTACAATGCACAGAATGATGGCAGAACATTGTTATTTATTGAAATCGACGGTGCAAAACAGCCTCTGTCTGTCAGCGTGGCATCTCTGACCATTGCGGAGAACATGGCGGATCTGATTGATGGCTACTGTCGACTGTTTAATCACACAGACTCATCAGTGATAGCTggaccaaataaaaataaatctcaaGGTGTGCAGTTGCGCAACTCTCTTCCTGAAATTCCCTCCGGGAAGAAGACAGACAGCTTCAGATATAGCAACTCTGATATATACTGTGAAATCCCAGATGAAAAACCGCCCCCACCTGCAAAGGTTGGACTGTCCAGGAAAGATATTAGCCTGAAACGGATGCTGGGTGAAGGGTTCTTCGGGGAGGTTCATGAAGGAGTTTACCAAAAAAAGAATGGAGAAAAGGTCAATGTTGCGGTGAAGACTTGTAAAGAGTGTGCGCCTGACATCAGAGAGAAGTTTGTGGGTGAAGCAGTTATCATGAAGAACCTGGACCATCCACACATAGTGCGGCTGATAGGAGTCATTGAGGAAGACCCTGTATGGATCGTGATGGAGCTCTGTCAACAAGGGGAGCTGGGGAAGTACTTGACGAAAAATCAGCAGAGTTTAACCAGCGTGACTCTGGTTCTCTTTAGCCTACAGCTCTGCAAAGCATTGGTTTACCTACAGGGAATGAACATGGTTCATCGAGACATCGCTGTGCGAAATGTGCTTGTTGCCACACCGGAGTGTGTGAAGCTGGGTGACTTCGGTCTTTCCAGATACATAGAGGATGAAGAATATTACAAAGCATCTGTTACTCGTTTACCAATCAAATGGATGGCTCCTGAATCCATTAACTTCAGACGCTTCACTGCGGCAAGTGATGTGTGGATGTTTGctgtgtgtgtttgggagATTATGAATCGAGGTAAACAGCCGTTTCACTGGCTGGACAACCGTGATGTGATAAACCAACTGGAACAGGGCAACAGGCTGCCCAAACCTGAGCAGTGCCCTCCTGCCCTGTATTCGCTCATGACCCGCTGCTGGAGCTACGACCCGCGCGAGAGACCCACCTTCACTGAACTAGCCTGCAATATCAGTGATGTTCACCAAATGGAGAAGGAGTTGGAAGCTGAGAGAGAGCGAGACAAGGCTCGTAACATCCGGACTCTGGAGCCCAAGATTAACATTAGTGAACCTCCACCAAAGCCCTCCAGAGTCAACACTACCCGCTTTGGAAATACTCTTGGAGTCGGCCTACATCTTCAGCTTAATGAGGCTTTATGTGCAAGTTCACCAGATCTGGCCAGTCCGTGTGATTATCAGTCACCTGTGGACTCAACTAACCTCCTGTCCCTCCCGAAGACTCCAAACCGGCGACTAAGTCTTGGGGAGGGCGACTTCAGCTTCGGGCCGTCCAGTAAAGAAGATGCTCAGCGGCTGTGGCAGATGGAGAAGGATCGATTACAGGACACGCTGAAGATGCAAAAAGAGCAAATGGAGGAGGACACCAAATGGTTAAAGAAGGAGGAGAAGCTTCTAGACCCAATGGTTCATGAAGGAAGTAAAATTCCTGAGCCACCTGAACCACCACTCAGCTATGCTGAACTCCATCATCCTCCTTCAAAACCACCCAGAATAGCAGTGCAGCCTGCACCTACAGCTGAACTGGACCGCTCAGAGGACACCGTGTACCAGTGTGTCATGGACGTAGTCAAGGTGGTGGTGCAGCTGAAAAATGACATTAACACACTGTCGTCTACTGAGTACATCTCTCCTGTCAAGactgTCGGGCTGTCATTACGAGATCTGATCAACAGTGTGGATGACATACTACCAACTCTGCACATTTCTTGTAGAACAGAGATCGAAGGCACTCAGAAGCTGTTAAATAAAGACTTGGCTGAGCTCATCAGTAAGATGCGTCTTGCCCAGCAGAACGCCATCACCTCGCTGAAGGAGGAGTGCAAGAAACAGATGCTGACAGCGGCACACACTTTGGCCATGGATGCCAAGAACCTGTTAGATGCTGTAGATCAGGCTCGGGTGCGCTCTAATCTGGCCAAACCCAAGCCTGATGATCCAGACTCACCAGCAGACTAGAGGAGCTGATTCAGAGCTGAGTGCAGGACAAACTTACTCATTTGTTTGATAAGATTGTAATGCAGTAATAGGGCAATGCCAACACCAGAATGGGGCATGAAACAGCCAATAGAAAACCAGTATAGGTTTACTGATGCATGTTCTGTTCTCCATGGAAACTTTTATAATGTAGAGATCCAAGTAAAGCCGATGGGTATTCCAAAAAGTaaagttaaagggttagttcactcaaaaatgtaaattattttgttaatttctattcattttctttttcttttttgggtaaactaaccaTTTAACTTACTGTCATATTAAcataaaattttaagttgattaacctaaaacttttttttttttactgtgaactACAATTATATGAAAGAAGaaagaatgattaaaaacagtTTGTGCTTCGGAAGATATTATTGCTGTGTATGTTTTAAACAAGCTGCTATTGTTATTTGTTACACTtaacaggcccatagccagggagggttcgggtggtttgaaagaccccccattgacaaaggtccagaatttgtcccatactgTACATGAGTTCATCctattttgtcatattttgactgctgtgccatcataaattgtaaaaataactcATTAAAGAAGACCAAGTGGAATCTGA
>TCONS_00035520
ATGAGATGACTGTGTAATGGTGTGTGGATTTCTTTGAGGACGTTTCTAGGACATGGCGAGTGATGCAAGCACCCTCTCCTGGAAGGTACCCGCTCAGGACTGGGATGGGGGCATCAAAAGCCCTGACCTGGGTCCTGTTGGAGATGGCGGCCCCGTGAAGATCATTAAAGTTTGCTTCAGTAGCAGCAACAACCTTAGCAAGAACTTCAAACTGGTCAAATGTGACAGCTCATGGCAGATCAAGACTATTATCCAGTCTATTCTGATCAGTGGGCGTTTGGGCCCGAATGTGCAGAACCCGGGCTGCTTTGGCCTGAGGCTCAAACACCTCAAATCTGAGGAGCTTCACTGGCTGCACCCAGACCTGACTGTAGGCGAGGTGGAGCAGCGCTATGAGAGCCATCACGCCGAGGCAGAGTGGAGGTATGACCTCAGAATCCGCTACATTCCCATTGATTATATGAAGAGGTTAAGAGAAGACAGAACGTTCCTGTTGTATTTCTATCAACAGGTGCGCAGTGACTACATGCAGCATCATGCTAGCAAAGTTAGTGACGGCATGGCTCTACAGTTGGGCTGTTTGGAAATCAGGAGATTTTATAAAGACATGAATGCCAAAGGTCTAGAGAAAAAGTCCAATTTTGACCTGCTCGAaaaagacgTTGGTCTTGACCTGTTCTTTCCCAAAGGACTCATTGACAGTATGAagCAAAGGCAGCTCAGAAAACTCATACAACAGACATTTCAGCAGTATGCCATACTAAAAGAGGATGACTGTATGGTTAAGTTCTTTGAGACCTATGGAGAGTTCTCCAACTTCGATGAGGAAATATTCCCTTGCGAGCTAGTGCAAGGTTGGAGTTTAGCAGTGGATTTAGTCATTGGTCCTAAAGGCATTCGTCAGAGAACCAAAGCAGACTCCACGGCTCTCTGCCTTGCTGAATACAAACAAATCCGAAGTATCAAGTACAATGCACAGAATGATGGCAGAACATTGTTATTTATTGAAATCGACGGTGCAAAACAGCCTCTGTCTGTCAGCGTGGCATCTCTGACCATTGCGGAGAACATGGCGGATCTGATTGATGGCTACTGTCGACTGTTTAATCACACAGACTCATCAGTGATAGCTggaccaaataaaaataaatctcaaGGTGTGCAGTTGCGCAACTCTCTTCCTGAAATTCCCTCCGGGAAGAAGACAGACAGCTTCAGATATAGCAACTCTGATATATACTGTGAAATCCCAGATGAAAAACCGCCCCCACCTGCAAAGGTTGGACTGTCCAGGAAAGATATTAGCCTGAAACGGATGCTGGGTGAAGGGTTCTTCGGGGAGGTTCATGAAGGAGTTTACCAAAAAAAGAATGGAGAAAAGGTCAATGTTGCGGTGAAGACTTGTAAAGAGTGTGCGCCTGACATCAGAGAGAAGTTTGTGGGTGAAGCAGTTATCATGAAGAACCTGGACCATCCACACATAGTGCGGCTGATAGGAGTCATTGAGGAAGACCCTGTATGGATCGTGATGGAGCTCTGTCAACAAGGGGAGCTGGGGAAGTACTTGACGAAAAATCAGCAGAGTTTAACCAGCGTGACTCTGGTTCTCTTTAGCCTACAGCTCTGCAAAGCATTGGTTTACCTACAGGGAATGAACATGGTTCATCGAGACATCGCTGTGCGAAATGTGCTTGTTGCCACACCGGAGTGTGTGAAGCTGGGTGACTTCGGTCTTTCCAGATACATAGAGGATGAAGAATATTACAAAGCATCTGTTACTCGTTTACCAATCAAATGGATGGCTCCTGAATCCATTAACTTCAGACGCTTCACTGCGGCAAGTGATGTGTGGATGTTTGctgtgtgtgtttgggagATTATGAATCGAGGTAAACAGCCGTTTCACTGGCTGGACAACCGTGATGTGATAAACCAACTGGAACAGGGCAACAGGCTGCCCAAACCTGAGCAGTGCCCTCCTGCCCTGTATTCGCTCATGACCCGCTGCTGGAGCTACGACCCGCGCGAGAGACCCACCTTCACTGAACTAGCCTGCAATATCAGTGATGTTCACCAAATGGAGAAGGAGTTGGAAGCTGAGAGAGAGCGAGACAAGGCTCGTAACATCCGGACTCTGGAGCCCAAGATTAACATTAGTGAACCTCCACCAAAGCCCTCCAGAGTCAACACTACCCGCTTTGGAAATACTCTTGGAGTCGGCCTACATCTTCAGCTTAATGAGGCTTTATGTGCAAGTTCACCAGATCTGGCCAGTCCGTGTGATTATCAGTCACCTGTGGACTCAACTAACCTCCTGTCCCTCCCGAAGACTCCAAACCGGCGACTAAGTCTTGGGGAGGGCGACTTCAGCTTCGGGCCGTCCAGTAAAGAAGATGCTCAGCGGCTGTGGCAGATGGAGAAGGATCGATTACAGGACACGCTGAAGATGCAAAAAGAGCAAATGGAGGAGGACACCAAATGGTTAAAGAAGGAGGAGAAGCTTCTAGACCCAATGGTTCATGAAGGAAGTAAAATTCCTGAGCCACCTGAACCACCACTCAGCTATGCTGAACTCCATCATCCTCCTTCAAAACCACCCAGAATAGCAGTGCAGCCTGCACCTACAGCTGAACTGGACCGCTCAGAGGACACCGTGTACCAGTGTGTCATGGACGTAGTCAAGGTGGTGGTGCAGCTGAAAAATGACATTAACACACTGTCGTCTACTGAGTACATCTCTCCTGTCAAGactgTCGGGCTGTCATTACGAGATCTGATCAACAGTGTGGATGACATACTACCAACTCTGCACATTTCTTGTAGAACAGAGATCGAAGGCACTCAGAAGCTGTTAAATAAAGACTTGGCTGAGCTCATCAGTAAGATGCGTCTTGCCCAGCAGAACGCCATCACCTCGCTGAAGGAGGAGTGCAAGAAACAGATGCTGACAGCGGCACACACTTTGGCCATGGATGCCAAGAACCTGTTAGATGCTGTAGATCAGGCTCGGGTGCGCTCTAATCTGGCCAAACCCAAGCCTGATGATCCAGACTCACCAGCAGACTAGAGGAGCTGATTCAGAGCTGAGTGCAGGACAAACTTACTCATTTGTTTGATAAGATTGTAATGCAGTAATAGGGCAATGCCAACACCAGAATGGGGCATGAAACAGCCAATAGAAAACCAGTATAGGTTTACTGATGCATGTTCTGTTCTCCATGGAAACTTTTATAATGTAGAGATCCAAGTAAAGCCGATGGGTATTCCAAAAAGTaaagttaaagggttagttcactcaaaaatgtaaattattttgttaatttctattcattttctttttcttttttgggtaaactaaccaTTTAACTTACTGTCATATTAAcataaaattttaagttgattaacctaaaacttttttttttttactgtgaactACAATTATATGAAAGAAGaaagaatgattaaaaacagtTTGTGCTTCGGAAGATATTATTGCTGTGTATGTTTTAAACAAGCTGCTATTGTTATTTGTTACACTtaacaggcccatagccagggagggttcgggtggtttgaaagaccccccattgacaaaggtccagaatttgtcccatactgTACATGAGTTCATCctattttgtcatattttgactgctgtgccatcataaattgtaaaaataactcATTAAAGAAGACCAAGTGGAATCTG
>TCONS_00035521
GACTGGGGAACTTAAAGGAAATAGGAAAACATCAGGAGCACAGCTTTGCAAGATGAGATGACTGTGTAATGGTGTGTGGATTTCTTTGAGGACGTTTCTAGGACATGGCGAGTGATGCAAGCACCCTCTCCTGGAAGGTACCCGCTCAGGACTGGGATGGGGGCATCAAAAGCCCTGACCTGGGTCCTGTTGGAGATGGCGGCCCCGTGAAGATCATTAAAGTTTGCTTCAGTAGCAGCAACAACCTTAGCAAGAACTTCAAACTGGTCAAATGTGACAGCTCATGGCAGATCAAGGTATGACCTCAGAATCCGCTACATTCCCATTGATTATATGAAGAGGTTAAGAGAAGACAGAACGTTCCTGTTGTATTTCTATCAACAGGTGCGCAGTGACTACATGCAGCATCATGCTAGCAAAGTTAGTGACGGCATGGCTCTACAGTTGGGCTGTTTGGAAATCAGGAGATTTTATAAAGACATGAATGCCAAAGGTCTAGA

Function

symbol description
ptk2bb Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in several processes, including angiogenesis; epidermal growth factor receptor signaling pathway; and innate immune response. Predicted to act upstream of or within several processes, including regulation of actin cytoskeleton reorganization; regulation of bone mineralization; and signal complex assembly. Predicted to be located in cell junction; cell projection; and cytoskeleton. Predicted to be active in dendritic spine and focal adhesion. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in breast cancer and hypertension. Orthologous to human PTK2B (protein tyrosine kinase 2 beta).

GO:

id name namespace
GO:0045087 innate immune response biological_process
GO:0042127 regulation of cell population proliferation biological_process
GO:0030154 cell differentiation biological_process
GO:0030155 regulation of cell adhesion biological_process
GO:0038083 peptidyl-tyrosine autophosphorylation biological_process
GO:0001525 angiogenesis biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biological_process
GO:0007172 signal complex assembly biological_process
GO:0007173 epidermal growth factor receptor signaling pathway biological_process
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005925 focal adhesion cellular_component
GO:0043197 dendritic spine cellular_component
GO:0005102 signaling receptor binding molecular_function
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function
GO:0004715 non-membrane spanning protein tyrosine kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-020507-1 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in several processes, including angiogenesis; epidermal growth factor receptor signaling pathway; and innate immune response. Predicted to act upstream of or within several processes, including regulation of actin cytoskeleton reorganization; regulation of bone mineralization; and signal complex assembly. Predicted to be located in cell junction; cell projection; and cytoskeleton. Predicted to be active in dendritic spine and focal adhesion. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in breast cancer and hypertension. Orthologous to human PTK2B (protein tyrosine kinase 2 beta).

Ensembl:

ensembl_id ENSDARG00000039577

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035519 False 3790 mRNA 0.46 31 19827379 19864131
TCONS_00035520 False 3709 mRNA 0.46 30 19827380 19858936
TCONS_00035521 True 500 nonsense_mediated_decay 0.46 5 19851743 19864103

Neighbor

gene id symbol gene type direction distance location
XLOC_018023 NA coding downstream 38369 19735774 ~ 19789010 (-)
XLOC_018024 BX510657.2 coding downstream 53904 19773360 ~ 19773475 (-)
XLOC_018022 baalcb coding downstream 237001 19579835 ~ 19590378 (-)
XLOC_018020 NA coding downstream 280791 19543143 ~ 19546588 (-)
XLOC_018021 dre-mir-206-1 coding downstream 282633 19544648 ~ 19544746 (-)
XLOC_018026 kcnh5a coding upstream 100723 19964854 ~ 20182871 (-)
XLOC_018027 ppp2r5ea coding upstream 365455 20229586 ~ 20270191 (-)
XLOC_018028 si:ch211-212g7.6 coding upstream 410870 20275001 ~ 20312789 (-)
XLOC_018029 snapc1a coding upstream 450443 20314574 ~ 20324792 (-)
XLOC_018030 hif1ab coding upstream 462480 20326611 ~ 20355577 (-)
XLOC_017928 CU539064.1 misc downstream 9773678 10053405 ~ 10053701 (-)
XLOC_018017 BX842692.1 non-coding downstream 442302 19382427 ~ 19385077 (-)
XLOC_018032 BX649231.1 non-coding upstream 564197 20428328 ~ 20582501 (-)
XLOC_018035 NA non-coding upstream 747761 20611892 ~ 20613628 (-)
XLOC_018036 NA non-coding upstream 817185 20681316 ~ 20690788 (-)
XLOC_018040 BX004766.1 non-coding upstream 1467883 21332014 ~ 21332128 (-)
XLOC_018043 BX296520.1 non-coding upstream 2135025 21999156 ~ 22015295 (-)

Expression


Co-expression Network