XLOC_018038 (xrcc3)


Basic Information

Item Value
gene id XLOC_018038
gene name xrcc3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 20896622 ~ 20901558 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035550
AGCGCGATAATATGAAGGGTCAGTGCTTTAGCCGTTACGCTAACGCTattctctttttgttttgttaaaattaagTATTGTTCTTTATATGTATTGCTtcttactgcatgtctttgaagaAACGTAAATAAATATCGTTAGCCGGCTGGATTTAAGACTTTAATTTTGACAGACTATATGACACAATGACCGGGAAGTAAACATCGTGCAGTTCAAAATGTGCGCAAATAGttttagttaacgttagttgaaatgtttattcattgttttattaacgTTAAACTGTTATTATGGAGATTCAAGTTTGGTGATGGAGTGGGAACAACTTGAGCTGAATCCAAGGATTATTGCTGCTGTTAAAAAAGGCAATTTTAGATCAGCCAAAGAGATCCTGTGTGTATCTGGTCCAGATCTGCAGAGACTGACGCGCTTGTCAAAGGCTGATGTCCAGCGTCTTCATCAGGCGGTAGCGGCTTCTGTGCGCAAGTCTAAACCCGTCACAGCATTGCAGTTGATCCAGGGAGAATGTCCTGTTTTGGAGCCTGGACACCGGCTCTCTTTTGCCTGCCCTGTTCTGGACGGTCTGATGCGTGGTGGTCTCCCATTACGAGGAATAACAGAACTGGCAGGCGAGAGCGCTGCTGGAAAAACCCAGTTTTGTTTGCAGCTTTGCTTGTCTGTCCAGTATCCACAAGAACACGGAGGACTGAATTCAGGGGCTGTTTACATTTGCACTGAGGATTCTTTCCCTATCAAACGACTACGGCAACTCATTACCCAGCAGCCCCGGCTCAGACCTGACCTGCCGCCAGCCCTGATCCACAGTCTGCGTTTTAGTGACAACATCTACATCGAGCATGCAGCAGACCTGGAGgctctgcaggtgtgtgtgtctcAGCGTGTGCCGGTGCTGCTGAAGCGAGGTCTGGTCAGACTGCTAGTGGTAGACTCTGTGGCAGCTCTGTTTCGCAGTGAGTTTCAGGCTGATGAGGCCGTTCAGAGGTCTCGACATCTGCTGGCTTTTTCCAGTACGCTCCACCGCCTCAGTCACACATACGCTGCACCTGTACTGTGTGTCAACCAGGTTACAGATGTTGTTGACGGCCCAAATCCAGGAAGATGCGATTATGGACTGGTGGGCAGTAAAGTGCTTCCAGCATTGGGCATCGCCTGGGCCAATCAGGTGATGGTGAGGCTAATGCTCAGGAGGCTGGCAGGACAGGTCAAATCAGACAGCCGAAGCTGTGCTCCTCGAAAATTAGAAGTGGTTTTTGCCCCACACCTGCCTCGATCAAGCTGCCTGTGTGGGGTTTGGGAGGAAGGGGTGAGAGGAATCCTTGATGGAGACTCAGATCTGCAGACACAGTGATTCAGCAGATGGAGAACTCTCTCTCAGTACTACAGGACAGTTAATGGAGGTAATAGCTCAACATTTGTAAGGACTTTGTGAGGAATGGTTGCATTTTTACCATTTGAAACGAATATGCATTATTTCCAAGTACGTTTGTAAAATCAATTCAATTTTTTATAATActttaatttcttttcttttttttaaatattgatattatgtcctttaataaatgtttttttatgttttcaaatgttttttattctATCTGTAATAAGCGAAGTGAATAAAGGGTGATGCTTTCTCACTGCTGCCCTTGAA
>TCONS_00035551
GGCAAACCCCAGCTCTAAAGCGCGATAATATGAAGGCATTGCAGTTGATCCAGGGAGAATGTCCTGTTTTGGAGCCTGGACACCGGCTCTCTTTTGCCTGCCCTGTTCTGGACGGTCTGATGCGTGGTGGTCTCCCATTACGAGGAATAACAGAACTGGCAGGCGAGAGCGCTGCTGGAAAAACCCAGTTTTGTTTGCAGCTTTGCTTGTCTGTCCAGTATCCACAAGAACACGGAGGACTGAATTCAGGGGCTGTTTACATTTGCACTGAGGATTCTTTCCCTATCAAACGACTACGGCAACTCATTACCCAGCAGCCCCGGCTCAGACCTGACCTGCCGCCAGCCCTGATCCACAGTCTGCGTTTTAGTGACAACATCTACATCGAGCATGCAGCAGACCTGGAGgctctgcaggtgtgtgtgtctcAGCGTGTGCCGGTGCTGCTGAAGCGAGGTCTGGTCAGACTGCTAGTGGTAGACTCTGTGGCAGCTCTGTTTCGCAGTGAGTTTCAGGCTGATGAGGCCGTTCAGAGGTCTCGACATCTGCTGGCTTTTTCCAGTACGCTCCACCGCCTCAGTCACACATACGCTGCACCTGTACTGTGTGTCAACCAGGTTACAGATGTTGTTGACGGCCCAAATCCAGGAAGATGCGATTATGGACTGGTGGGCAGTAAAGTGCTTCCAGCATTGGGCATCGCCTGGGCCAATCAGGTGATGGTGAGGCTAATGCTCAGGAGGCTGGCAGGACAGGTCAAATCAGACAGCCGAAGCT

Function

symbol description
xrcc3 Predicted to enable ATP binding activity; ATPase, acting on DNA; and DNA binding activity. Predicted to contribute to four-way junction DNA binding activity. Predicted to be involved in DNA metabolic process. Predicted to act upstream of or within DNA repair. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Rad51C-XRCC3 complex. Predicted to be active in replication fork. Human ortholog(s) of this gene implicated in breast cancer; familial melanoma; and pancreatic cancer. Orthologous to human XRCC3 (X-ray repair cross complementing 3).

GO:

id name namespace
GO:0071140 resolution of mitotic recombination intermediates biological_process
GO:0090656 t-circle formation biological_process
GO:0045003 double-strand break repair via synthesis-dependent strand annealing biological_process
GO:0000722 telomere maintenance via recombination biological_process
GO:0006281 DNA repair biological_process
GO:0005634 nucleus cellular_component
GO:0005657 replication fork cellular_component
GO:0033065 Rad51C-XRCC3 complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0000400 four-way junction DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0008821 crossover junction endodeoxyribonuclease activity molecular_function
GO:0008094 DNA-dependent ATPase activity molecular_function

KEGG:

id description
ko03440 Homologous recombination
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-050320-116 Predicted to enable ATP binding activity; ATPase, acting on DNA; and DNA binding activity. Predicted to contribute to four-way junction DNA binding activity. Predicted to be involved in DNA metabolic process. Predicted to act upstream of or within DNA repair. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Rad51C-XRCC3 complex. Predicted to be active in replication fork. Human ortholog(s) of this gene implicated in breast cancer; familial melanoma; and pancreatic cancer. Orthologous to human XRCC3 (X-ray repair cross complementing 3).

Ensembl:

ensembl_id ENSDARG00000017928

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035550 False 1672 mRNA 0.45 7 20896622 20901540
TCONS_00035551 True 777 mRNA 0.54 6 20897050 20901558

Neighbor

gene id symbol gene type direction distance location
XLOC_018037 ckbb coding downstream 74833 20816747 ~ 20821789 (-)
XLOC_018036 NA coding downstream 205834 20681316 ~ 20690788 (-)
XLOC_018035 NA coding downstream 282994 20611892 ~ 20613628 (-)
XLOC_018034 ppm1ab coding downstream 285559 20600971 ~ 20611063 (-)
XLOC_018032 BX649231.1 coding downstream 314121 20428328 ~ 20582501 (-)
XLOC_018039 btbd6b coding upstream 26269 20927827 ~ 20932782 (-)
XLOC_018040 BX004766.1 coding upstream 430456 21332014 ~ 21332128 (-)
XLOC_018041 si:ch211-207i1.2 coding upstream 736839 21638397 ~ 21806170 (-)
XLOC_018042 daam1b coding upstream 914055 21815613 ~ 21994901 (-)
XLOC_018043 BX296520.1 coding upstream 1097598 21999156 ~ 22015295 (-)
XLOC_017928 CU539064.1 misc downstream 10842921 10053405 ~ 10053701 (-)
XLOC_018023 NA non-coding downstream 1107612 19735774 ~ 19789010 (-)
XLOC_018044 NA non-coding upstream 1141952 22043510 ~ 22070176 (-)
XLOC_018048 NA non-coding upstream 1487558 22389116 ~ 22432496 (-)
XLOC_018051 NA non-coding upstream 1750418 22651976 ~ 22659422 (-)

Expression


Co-expression Network