XLOC_030086 (trpm6)



Basic Information


Item Value
gene id XLOC_030086
gene name trpm6
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 25317061 ~ 25358683 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00058830
CTGGCTGGAAGTGTTTATGACTGACTCACTCATCTGTCAAGGAGATTTGAGGAGACATGTCTAGATGCACTTGGATCCAGGCCACCTTTTGCAAGCGAGAATGTGTCAGATTTCTGCCAGCCTCACGTGATCATCACAGGTGTTATCCAGTGTGTCAAGTGTGCCAAAGCTTAGTAAGATGCTGTTGTGGGAGGCTGATCGCAGAGCATGTGGGCCCATACTCTGGTTTGCTGGGACATGACCCTGGGTCTGGCTCTGCAGAAGAGGAGGAGTGGTCTGTGCTGCAGCACACCAGCCTCAGCCCCACTGATGCCTTCGGATCACTGGACTTCCAGGGCAGCTCAAAGCGTGCGTGTCGTGCTAAGTATGTGCGTCTTTCCTGTGACTCTCCACCAGAGCTCCTGGTCCAGCTGATGCTGAGAGAATGGCACATGGAGATACCCAAGCTGGTGATCACCGTACACGGAGGGACAGATAACTTCCTTCTGTCTCCACGGGTGTGCCAGGCCTTCAGCACTGGGCTCGTCACAGCTGCAGAGAGCACTGGAGCATGGATACTGACAGATGGCATCAATACGGGTGTGTCCAAGTATGTTGGCGATGCTGTAAAAATGTATGGGTCACATGACCACAGGAAGAGAAATGTTGTAGGCATCACACCCTGGGGGATTATTGAGAATAACAGTGACCTTATTGGCCGGGATGGTTTGAGGCACTACCAGGCTTTAGGAAATCCTCTGAGTAAACGTGCCAGTCTGAACGGCATGCACTCACATTTCCTCTTGGTTGATGATGGAACTATTGGTAAATCAGGTTGTCAAATAGAGCTGAGGAAGAGACTTGAAAGGCATATACACTATCAGAAGATCCACCCTAGGCTGCCTCAGCATGTGCCTTTAGTATGTGTCGTAGTAGAAGGTGGTCCTTCCGTCCTCTCCGTTGTGCTGGAATATGTGTGCAGAACGTCTCCTGTCCCTGTGCTGGTGTTTGAGGGAACAGGGAGAGCTGCAGACATGCTGGCtttaatacacaaacaaacagctGTAGACAGAAAGTTGGATTCTGATATTAAAGAAGACGTCCTGCAGAGGATTCAGGATTCGTTTGGGGTTGAGAGATCAGAATCCACTGAACTCCTCGACATTCTTATGGAATGCATGGAGCATAGAGAGCTTATCAGCATTTTTGACTCTGAATCTGAAGACCTTCAAGAGGCAGATGTTGCAATCCTGTCCACATCGCTGAGAGGGACGAGAGCTTCCCCCGAGGAACAGCTGAGTCTCACTCTGGCTTGGGACAGAGCTGATATTGCAAAAGACCACATTCTGGTCTATGGGCAACAATGGCAGGTAGGATCTCTGGAGCAGATCATGCTGGATGCGCTGATAATGGATCGCGTCAATTTTGTAAAGCTGCTAATTGAGAATGGCATGACCATGAGTCACTTCTTGACAATCTCTCGTCTGGAGCAGCTCTACAACATACAAACAGGCTCCTCACATCATTTCCTTCGACATGTTATTGCAGATGCCAAACAGACTCGCCTGCCTGCTGTTTATAGGATATCTTTAATCGACATTGGAATGGTGATTGAATACCTGATTGGTGGAGCATATCGAAGCACATACACACGCAAGAGATTCAGAACCATGTACAGTCGCTTACATAACCCAGCTAAGGAGACATCCAGCCCGTTCAGCAAGGCCAAGAAAGTAGCTCCAGCTCCAGAAGCCACTCCACCTCGCTCTCATTTCCGCAGAACCGCTCAGCCATACAGACACCAGGAAGGTGGTGTAGCACCTCAGGACCAGAAGTCGGACCCGATCCCCGACTTTGTATGCACTTTTAACGACCTGTTTGTGTGGGCAGTGCTCAAGCATCGGCAAGAGATGGCGCTGCTCCTGTGGCAGCATGGAGAGCAGGCTATGGCCAGGGCGGTTGTGGCCTGCAAACTCTACCGCACTTTGGCAATGGAAGCCAAGGAGAGCAATATGGGAGACACCATGGCCGAGGAGCTGAAGAAGAACTCTCTAGAGTTTGGACAGTTGGCTGTGGATGTCCTGGATCAGGCTTTCAGAGAGAATGAGCGCATGGCGATGAAGCTGCTGACCTGGGAGATGAAGGATTGGAGTAACTTCACCTGTCTGCAAATGGCCGTCTCCTCAGGACTCAGGCCCTTTGTGGCTCACAACTGCACTCAAATGCTGCTCACAGACCTGTGGATGGGCCGTCTAAACTTGAGCAAGAACTCCTGGTTTAAGATCATCGGCAGTATCCTGATGCCTGTGGCCATTCAGTTGCTAGAGTTTAAGAGTCAGGCAGAGATGTCCCATGTTCCTCAGCTCCAGGAAGCCTTGCAGTTTGGGTGGGACACTGTGCCATCAGAGCAAGAAGGGGCAGAAAAAGCAGTTCCAGGTGATGAGGAGAGAGGCAGCAGTTGTCTTTATCCCTGGACCAGAAAGGTGTATGACTTCTATACTGCTCCGGTGGTCAAATTCTGGTTTCACACTATGGCGTTTTTGGGATTCCTCATGATGTTTGCTTATACTTGTTTGGTGAGGCTGAACGAGACACCCAACATTCAGGAGTGCTTGGTCATGACTTACATCCTGGCCATGGCGGTGGAGAAAGCTAGAGAGGTGTTGGTTTTGGAGCCTAGGAAGTTCACTAAAAAGCTGAAGGTGTGGTTCAGTGAGTACTGGAATATCAATGACTTCCTGGGAATCCTCTTGTTCCTGGTCGGGGTCTCCCTCCGGTGGCATCAAGAAACACGCTTAGCCAGTCACATAGTCTATTCTTTGGATTTTGTCTTCTGGTCTGTCAGGCTTCTGGATCTATTCGCTGTCAATCAGCATGCAGGACCATACCTGACAATGATAACTAAAATGATGAGCaacatgttttatattgtaaTCATTATGGCACTTGTGCTGGTTAGTTTCGGGACGTCGAGAAAGTCTATCTTGTCCCCTAATGAGGATCCATCCTGGACTCTGCTCAGAGATGTTGTCTTCCAGCCATACTGGATGATCTTTGGAGAAGTGTATGCTGGGGAGATTGATGCCTGTGCTAATCCTGAAACCTGTGTCCCGGGAGCCTTCCTCACCATCTTCCTGCAGGCCGTCTACCTGTTCATTCAGTACATCATCATGGTCAATTTGCTCATTGCCTTCTTCAACAATGTTTACAATGAAATGAGCACCATATCCCGTAAGCTGTGGAAATACAACCGCTATCGTTACATCATGACTTATCAAGAGAAGCCGTGGCTGCCACCTCCTCTCATCTTTCTCAGTCACATTACTCTGTGTCTCAGCTCAATGTGGCAAAAGCATAGAAAGGCATCCAAAAGGGGAAGAACTGGtctgaAATTAATCCTTGCCCCCGATGACCTGAAGCGGTTGTATGAGTTTGAGGAGAAGTGTGTTGCTGGATATTTCCGAGACCAAAAGGAAAGTCAACAAGGCAGTCAGATCAACCGAATTCGCTCTGCAGCTGACAAGGCTGAAGAGATGGCTGGAATATTAGTTGAGGTTGCAGAGAAGGTCAATATCATCCAGGACAATCTGCGTACTTTAGACACTAACTTGGGCCAATTACAGGACTTGTCCGCTTTAGCAGTGGACACTCTAAACCTCCTCTCAGCCACAGACAATCAACAGCAAGAGGTGGCCCGTCTGGGTCAGAGCCATCCACATGCTTGCCGCCATGAGCAGGTGTCCCATAGCTGCTGTCTCCGCATTGGTGGAAGTGTAGCACCGAGCCAAGCACTCCCGTCACCCAAACACTACCGCAGCATGCCTCCATCCCTGCTTAGAGGTTTGGGACCTGGCCGACAGCGTCTCTCAATGGAGTTACCACCAGGAACGAGCGTTGGACCCTTTGAGGTCAGAAGCAAATGCCTATTGGGAAGCCCAGAGGAAGAGGATTGTCATTTTCGGTGGCCTCTTTTACGTGGCGATTCGAGAGAAGGTGTATCAATGGATTGTCATCTTTCTTTACCCCACTTATGCACTGGATGGAGGGACAGGGGAATGTATGGATCAGGGGAAGCATCCCGTGCCAGTTCTCCAAACATGCCTTTAATGAGGGACTTCCAGCTTCATCCCAGCCACGAGGAATCCATGGAGGAGGAAGACGATGACGAGGATGACCTGCACTCTTTATCCAGAGCCTCTAGCCACACGTTCTTGCTCACGGACACTCAGAGGGACATGGATGGGGCGATGGGGATCAGAAATCCGGCGTTCTATAAGCTCGACGAGGGTGGACATTTCTTAAGGCCTCATGACGTTTTAAGCAGGAAATTTGAAGCCTATGGTTTGGAGCAGAGCCGGTCTCTTTCGGCTAGTGTGGAGTCTATGGCCATGCCAGACACGTCAACATCTGAGCAGGGCAGACGGATCTATCTGACGCCGCCTCATCACAGCCATGACCATAAAGGATTGTCAAAGCTATTTAGGAGGCAAAGATCATTTGGGAAGAAGTCTGTGAGAAGCAGAGCAGGAACTCCTGAAGAGGTTAAAGCAGATGAAACACGGGGGCGACTGCATGAGTTTGACTCGCGTAGAAAAATGAAGAGGAAAGTAAAAGGCCTTTTTGACCGGAGATTCAGAACCTCAGTCAGTCTAACCCAGCtgaatGTTGACCAAGTGGACATCACAAAATTGGCCCCATCGTGGCTGAGTTCCGGGCAGCCCCTGCTCAGTAGCTGGACCAGACCCATTAGTCAAAGACCCTCGGTAAGCAGTATGACAGacgTAAGGAGCTCTACATTTAAGTTGACTGAAGATTTAGGCCAGCATTACTCAGCAATGGAGAGAAACAACCTAATGAGATTGGCTCACACTATACCCTTCACACCTGTGTCATTATTGGGCGGCGTTGAGGTCTGCATTTACACACTGGAGGAGTCAGTTGGTGATCCGTCCTCCAGTATCTCCACGTGGCTTCAGAATGGACGTACAGCTGTTCTTCAGCCTTTAGCCCATCAGGAGGTGCTGGATGGGGGACTGCGCAGGGCCACAAAGGTGGTGTGCACCTGGGCCGAGGGTGATGTGTTGAAGCTGGGCTCAGTGTATGTGGTGAAAGCCTTCAGGCCAGAAGTGGTACGCATCTGGCAGAAAGTGTTCCCGATTAGCACGTCACTTCACCTCTGTCTGCGGGAAATTCAACAACAGAGAGCGGCACAGAAGCTCATGCAGCGATTCAACCAAGTTAAACCCAGCAGTGTGCCCCACAGTCCTAGGTTTCTGGATGTGTCCTTGCTGCACTGGCGCTCTGATGGCCAGTGGTTGACTGTAGAGAATAACATGAGTGGTCATTTCAGAAAATACAACAATAACACGGGTGAGGAAATCTTGCCCTCTTCTGGCCTGGAGGAAACAATACTAGCTTTCTCTCACTGGACATACGAGTACACCAACAAGGAACTGCTAGTGCTGGATCTACAAGGTGTGGGAGCAGACCTAACAGACCCCTCGCTGATCAGAGTCGATGATAAAAGCTCCCCTGGAGAGATGGCGTTTGGACCTGCCAATTTGGGCGATGATGCAATCCAGAGCTTTGTTCTCAAGCACACCTGCAACTCCTGCTGCAAGAAGCTGGGTCTCTCAGATTTGAGGAGTTGCGGGAGCCTGAAGAAGTCTGTTCCTGCCTTTGATGAGACCAGCTGCACAGCTTAACCTTTGACCTTCAAGGAAACTTTTAGCAGATCCACAGAGAGCACGCAGAGGCACGGCTCAGGTTCATGGGGGGACTCCTGTTCATACACTATATACTTTTTTACAGGctgaatatactgtatgtaaagaACTGCTGTCTATGGGGTAAAAGCAATGTGCACAATGTTTGAAAGTGGgcatcatttttttaaagatcagACTTTTCCCAGCAAACaatgttgtgtttaatagacgtctaataacatctaaacgtagaccgcttggctaaaacaaggcttaccttgggctgtcagtgaaaatctaatagacatctaagaatagcccaaaacagtcgtcaaatagacagattagacagacttgatatgtgtagtcattcatttctgtttatttcatgactagtctagttttggcctatttgaTTTTAAATGACAGCCCAAATTAACCTTGCTTTAGCTAAGATGACTGtgtttaaatgtctattagacatcttttaaaatcaGAAATTGCTGGCTGGGTTTCCTCATTTATAAGTGCATGCTTAAAAGCTGGTTAAGACAATGcataaaatatctatatttttacaTTCAAAGATAATATGCAAGGCTTGATATAAACCTTGTTTTGTTTTCCAgggaataaaaaattaaacatc

Function


symbol description
trpm6 Predicted to enable ATP binding activity; calcium channel activity; and protein serine/threonine kinase activity. Predicted to act upstream of or within calcium ion transmembrane transport; protein phosphorylation; and protein tetramerization. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including digestive system; heart; opercular flap; pleuroperitoneal region; and scale. Human ortholog(s) of this gene implicated in intestinal hypomagnesemia 1 and metal metabolism disorder. Orthologous to human TRPM6 (transient receptor potential cation channel subfamily M member 6).

GO:

id name namespace
GO:0051262 protein tetramerization biological_process
GO:0006468 protein phosphorylation biological_process
GO:0055085 transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0006812 cation transport biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0005216 ion channel activity molecular_function
GO:0005261 cation channel activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
ko04978 Mineral absorption
ko01001 Protein kinases
ko04040 Ion channels

ZFIN:

id description
ZDB-GENE-111212-1 Predicted to enable ATP binding activity; calcium channel activity; and protein serine/threonine kinase activity. Predicted to act upstream of or within calcium ion transmembrane transport; protein phosphorylation; and protein tetramerization. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including digestive system; heart; opercular flap; pleuroperitoneal region; and scale. Human ortholog(s) of this gene implicated in intestinal hypomagnesemia 1 and metal metabolism disorder. Orthologous to human TRPM6 (transient receptor potential cation channel subfamily M member 6).

Ensembl:

ensembl_id ENSDARG00000103454

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00058830 True 6336 mRNA 0.48 39 25317061 25358683

Neighbor


gene id symbol gene type direction distance location
XLOC_030085 NA coding upstream 2309 25311263 ~ 25314752 (+)
XLOC_030084 carnmt1 coding upstream 7512 25304499 ~ 25309549 (+)
XLOC_030083 NA coding upstream 67385 25248198 ~ 25249676 (+)
XLOC_030082 paxx coding upstream 229769 25084385 ~ 25087292 (+)
XLOC_030081 mrpl41 coding upstream 241882 25072894 ~ 25075179 (+)
XLOC_030087 kifl coding downstream 227186 25585869 ~ 25587613 (+)
XLOC_030088 si:dkey-96l17.6 coding downstream 237551 25596234 ~ 25605668 (+)
XLOC_030089 zfand5a coding downstream 322159 25680842 ~ 25694362 (+)
XLOC_030090 NA coding downstream 342342 25701025 ~ 25710432 (+)
XLOC_030091 abhd17b coding downstream 375091 25733774 ~ 25757578 (+)
XLOC_030079 NA non-coding upstream 437496 24873805 ~ 24879565 (+)
XLOC_030078 NA non-coding upstream 481744 24816325 ~ 24835317 (+)
XLOC_030075 NA non-coding upstream 844985 24469471 ~ 24472076 (+)
XLOC_030094 dre-mir-204-1 non-coding downstream 613385 25972068 ~ 25972160 (+)
XLOC_030106 NA non-coding downstream 1120991 26479674 ~ 26481301 (+)
XLOC_030114 NA non-coding downstream 1537351 26896034 ~ 26906786 (+)
XLOC_030117 NA non-coding downstream 1591028 26949711 ~ 27051459 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000339_02930318_02952950 TRPM6 coding CI01000339 null 2930318 ~ 2954199 (+)