XLOC_030710 (dcc)


Basic Information

Item Value
gene id XLOC_030710
gene name dcc
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 31748 ~ 201600 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00059835
ATGGGCTGCGTCACTGGAGATATTCGCCGACTTTCCGCGCTCCTCATCGGGCTGCAGGTCCTCTACACACACGGTTTGGAGTCTCCGCGGGGGTTTGTGGATCTGCGGTTTGTGCTGCAGCCGCAGGACGTGGTGACGGTACGGGGTGGAGTTCTGCAGCTGGACTGCGATGCGCTGTCGGATCAGGGCGTCCCCAGCATCTCCTGGAAGAAAGATGGAGTTCTGTTGAGTGCAGTAGTGGACGAGCGCAGGCGTCAGCTCTCTAATGGATCCCTGCTAGTGCAGAATGTGATGCATTCGAGACACCACCGGCCGGACGAGGGCTCCTACCAGTGTCTGGCCTCGCTGGAAGGCATCGGGGCCATCGTCAGCCGCACCGCACGCGTCACCGTCTCCGGTCCTCTGCGTGTGCTGGTCTCCACAGAGTCAGTATCTGCTCATCTGGGGGATACGGCTCTGCTGCGCTGCGAGGTGACGGGTGACCCCATGCCTGTGGTGCGCTGGCAGAAGAACCGAGAGGACCTGCCCTTGACCTTTGACCCCGACAGCAGAGTGGTCATCCTGCCCTCGGGGTCTCTGCAGGTCAGCCGGGTGCAGCCGCCGGATTCGGCCACGTATCGATGCCTGGCGGAGAATCCTGGCAGCGCCCGCACCGGCACAGATGCAGACCTGCGCGTACTGCccggtgagagagagagacaagcaGATCTACACACACTTACATTTGTGTGTgttctctatgtgtgtgtgttggcatttgtgtgtgtaaaccccccatccaccccttctcctcctttcctcttttgccgagaggagctctcgagaacacctgatctcgtactcgcctcacatgctttactggcgggagccctggcctcaactatctccgagctcatggttctctcccgggacagcatgccaaacctgctaacaagttgtcaaacagtatctaagtTGCCGCCTCAGTTTCTCAACTACCCGTCAAACACATATGCGTATGAAAGCTCAGACATTGAGATGGAGTGTGCAGTGACTGGAAACCCACAACCTGTCGTCCGCTGGGTGAAGAACGGAGAGGTCGTTGTTCCCAGTGACTACTTTCAGATCGTGGATGGTGGTCATCTGCAGATTCTGGGTCTGGTGCGCTCAGATGAAGGCTTTTATCAGTGCATCGCAGAGAATGAAGCGGGGAACAGTCAGGCCATGGCTCAACTCATCCTGCTGCAGCCCGTTACCCCGCGCTCCGCCGTTTCTCCCTCCGCCCCTCGTGACGTGGCCCCCGTCCTCGTGTCCAGCCGATTCGTTCGTCTGAGCTGGCGGCCCCCGGAGGAGCCCCGCGGCCCAATACTCACCTACGGGGTCTTCTACTCAGAGGAGGGCATCAACAGggAGCGGTCAGTAAATGTGACTGAGGCTGAGAGTCTGCAGCTGACGGTCAGTAATCTCCGCCCGGAGGCCAGCTACTCCTTCAGGGTTCTGGCATACAATGAGCAGGGGCCCGGAGAGAGCTCAGAGGCCATACGGCTGTCCACACAGGCTGAGCttTTAGTTCCGGGTCCGGTGGAGAATCTCCAGGCTGAAGCGGTTTCTCCGACCTCAATCCAGGCCTCGTGGGATCCTCCAGCTCCAGCAAACGGCCCCGTGCAGAGCTACCGGCTGCTGTGGACTGAGACCTCCAGCGGGAAAGAGCAGAATGTGGAGGTGGTGGGTCAGAGCTACAGGATGGAGGGACTGAAGAAGTTCACTGAGTACAGTTTGCGAGTGCTGGCGGTGAACCGACACGGCCCCGGGGTCTCGGATAAAGACACACTCATCACCACGCTCTCAGACGtGCCAAGCTCTCCGCCGCAGAACGTCTCGCTGGAGGTGGTGTATTCACGCGTGAgcttgcgctcTTGGCTCTTAGGCTTCCTGACCAGTCAGAACATCAAGTATTGTGTGTTCATATCGTCTGCAGTCAAACACAGGTCACAGTCCATTTGGAAATCTCTGCTcccttattttatttggctgGAGAAGGGCAGTCAGTACAGTTTCCAGGTGTCAGGGATGACGGTGAACGGGACGGGGCCCAGCAGCGAGTGGCTGACTGCTGAGACACCTGAGAACGACCTGGAcgAGTCTCAGGTGCCGCATCAGCCCAGCTCTCTGCATGTGCGTCCGCTCCCCAACAGCATCATCATGAGCTGGACGCCGCCGCTGAACCCCAACACACTCATCCGAGGATACACCATCGGCTACGGCGTCGGCAGCCCCTACGCTCAGACCGTCAGGGTGGACAGCAAGCAGAGATACTACTCCATAGAAAACCTCGACCCGTCAGACCCGTCTGATGACGATCTGTTCCATCTGTTTGATAACGTTGCGACCGCGGCCCCAGACTCGTCCTCCGCGCCCATGATTCCCCCTGTAGGTGTGCAGGCGGTGGCGCTGACCTCAGACTCGGTGCGCGTCTCCTGGGCCGACAACTCCATTCCCAAGAACCAGAAGAGCTCCGAGGTGCGCTACTACTCCGTCAAGTGGAGGACCAGCCACTCCACCAGCGGCAAACACaagTCGGCTGATACGACAGCTCTGAGTCACACAGTCACAGGTCTGAAGCCCAACACCATGTATGAGTTTTCAGTGATGGTGACCAAAGGACGCAAATCCAGCACCTGGAGTATGACTGCACACGCTACTACATATGAAGCagCACCAAGCTCCGCCCCAAAGGACCTCACTGTGATTGGTCGAGAGGGTCGACCACGAGCCATTTTGATTAGCTGGCAGCCGCCACTGGAGGCCAACGGACGAATCACAGggtttATCCTCTACTACACGCTGGAGAAGAATCTGCCGATAGATGATTGGGTGATGGAGCCCATCAGTGGAGACAGGCTCACTCATCAGGTGCTGGACCTCAATCTGGACACCGTCTACTATTTCCGCATCCAGGCCAAAAACGCTAAAGGAGTCGGGCCGCTGTCGGACCCCGTGCAGTACAGGACCTCCAAAGTTGAGCATCCGGATAAGATGGCCAATGATCAAGGTCGTCATGGAGACGGGGTGTACTGGCCCTCTGATAATAACCCCATTGACATGAGCAGCCTGAACGAGGCTCCAATCGGGCAGATGCGTCCCCCTCACGGCAGCGTGACCCCGCAGAAGAACAGTAATCTGCTGGTCATCATCGTGGTGTCGGTGGGAGCGGTGACGGTGGTGGTGGTGCTGATTGTGGCGCTCATCTGCACCCGACGATCATCCGCTCAGCAGAGGAAgaagcGTGCAACACACAGTGCAGGCAAGCGTAAGGGCAGCCAGAAAGACCTGCGTCCTCCAGACCTGTGGATCCACCATGAGGAGATGGAGCTGAAGAACATGGAGAAGCCCTCAGGCTCCGCCCCCTCCGGCCGAGACTCACCAATCCAGAGCTGCCAGGAGATCCCTCCAGTCAGccacagccaatcagagagccAGATGGGCAGCAAGAGCAGCCACTCAGgtgcgGATGCTGATGAATCCTCCAGCAGTATCTCCACATTAGAGAGATCTTTAGCTGCCAGAAGAGCGACGCGCACCAAGATGATGATTCCCATGGACTCACAGCCCAGCAACACA

Function

symbol description
dcc Enables netrin receptor activity involved in chemoattraction. Acts upstream of or within with a positive effect on commissural neuron axon guidance. Acts upstream of or within neuron differentiation and regulation of axon extension. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; neural tube; pleuroperitoneal region; posterior neural rod; and primary motor neurons. Human ortholog(s) of this gene implicated in colorectal cancer; congenital mirror movement disorder; esophageal cancer; and esophagus squamous cell carcinoma. Orthologous to human DCC (DCC netrin 1 receptor).

GO:

id name namespace
GO:0016358 dendrite development biological_process
GO:0048846 axon extension involved in axon guidance biological_process
GO:0030516 regulation of axon extension biological_process
GO:0071678 olfactory bulb axon guidance biological_process
GO:0031103 axon regeneration biological_process
GO:0021952 central nervous system projection neuron axonogenesis biological_process
GO:0021960 anterior commissure morphogenesis biological_process
GO:0033564 anterior/posterior axon guidance biological_process
GO:0048665 neuron fate specification biological_process
GO:0007411 axon guidance biological_process
GO:0007155 cell adhesion biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0038006 netrin receptor activity involved in chemoattraction molecular_function

KEGG:

id description
ko04360 Axon guidance
ko05200 Pathways in cancer
ko05210 Colorectal cancer

ZFIN:

id description
ZDB-GENE-011101-2 Enables netrin receptor activity involved in chemoattraction. Acts upstream of or within with a positive effect on commissural neuron axon guidance. Acts upstream of or within neuron differentiation and regulation of axon extension. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; neural tube; pleuroperitoneal region; posterior neural rod; and primary motor neurons. Human ortholog(s) of this gene implicated in colorectal cancer; congenital mirror movement disorder; esophageal cancer; and esophagus squamous cell carcinoma. Orthologous to human DCC (DCC netrin 1 receptor).

Ensembl:

ensembl_id ENSDARG00000104282

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00059835 True 3600 mRNA 0.58 24 31748 201600

Neighbor

gene id symbol gene type direction distance location
XLOC_030712 NA coding upstream 48148 249748 ~ 252101 (-)
XLOC_030713 NA coding upstream 97545 299145 ~ 307140 (-)
XLOC_030714 NA coding upstream 99278 300878 ~ 301152 (-)
XLOC_030715 HOOK3 coding upstream 113583 315183 ~ 417535 (-)
XLOC_030716 NA coding upstream 125084 326684 ~ 337090 (-)
XLOC_030717 NA non-coding upstream 196705 398305 ~ 399726 (-)

Expression


Co-expression Network