XLOC_030925 (kremen1)


Basic Information

Item Value
gene id XLOC_030925
gene name kremen1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 16151944 ~ 16274058 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00060119
ATTCATCCGCGCGCCGCATCAGCTCGACTGACCTGACTGGACTTCAACACACTTCACCTGCGAGAACAGAGGACCAGAAGCTCAGACAGATCACAGACTACAGTTACAGTAGCTACAGAAGAGCGATGGATTCGTGGAGAGTCGCAGCTTTGCTCCTTGCCGTCTGCTTCAGCGCTTCAGCTACTGAGCACTTCCACACGGaGTGTTATACAGCGAATGGTGAGGACTACAGAGGTCGACAGAATCAGACCAGTCTGCAAGGAGGAAGGCCGTGCCTTTTCTGGAATGAAACATTCGAACGTCCATATAACACCAACAAATACCCCAATGGAGAAGGAGGGCTTGGGCAACACAACTTCTGCAGGAACCCAGATGGAGATGTCCGTCCCTGGTGTTACATTGCAGATCTCGAGGACGGATCTTACTGGAAATACTGCGATATCCCCACCTGCCAAATGCCAGGTAACCTGGGCTGTTTTAAGGACAGCGGTGATCCGACACCTTTATCTGGAAGCCACCAAACCTCCACCAAACTGACCATTCAGAACTGCATCAGCTTCTGCCGCAACCAAAGATACAAGCTTGCCGGGATGGAATCAGGCTATGCTTGCTTCTGCGGCGATGACCGTGAATATCACCGTCACGGTGATGCTCCGAACACAGAGTGTAACCATGTGTGTTTTGGAGATCACACTCAGCCGTGTGGAGGAGATGGACGCATCATCGTCTTTGACACAAAAGTAGGTGCTTGTGGAGGAAACTTCACATCACCTTCAGCAGTGATCTACTCTCCCGACTTCCCAGGCAAATACAGGTCTGGCAGTGTCTGCTACTGGACCATTCAGGTTCCAGGTTCTTCTGTTATTCTGTTCAACTTTACTTTCTTCAGTATCGTGGACCAAAAAGACATGGTGGAGCTGTTGGATGGTAAAACCAACCAGGTTGTGGCACGATTTGACGGCCGCAATCCTCCACGGGACATCGTGAATATCACCGCAGACTttgtcattttgtatttttactcCGATAGGACAAATGAGGCACTGGGGTTTTCTGTTGTTTATCATGCTTTAAGAAATCCAGCATTCAGACCTGAAGAGGAGGACAATGGTGATGAAGAAGACACAAGTACAATGCGGCCGAACTCAGGAAGCACTACAACAAAATCAAACACCAGTCAGAGTGGAAAGTCCTCCCATCTCTACTACGTGATCACATCAAGTCCTGCAAACATGCCAGGTCAGTGGCATGGACCAGGCCGGACTGCGGGCCACAACACCAtgtggacCATCTATGCGTTAGCTGCCCTGCTAACGCTAACAGTCATAGCCATGGTCGCTAAACTGCTTCTGCATCTTACTGTAAAGTCCCCGTCCATCCCATCAATAAGCGGGTCAGAATCATGCGCACAGAGCACTACATCTGAACCCTGGATCATCCTCTACAGACCTTCCACCATCTCTCTGTTCAAGAAGAAGCTCAAAAACCACCACGGAGACCTCAGCCCACTTGTGGGAAACTAACCTCAACGCCTCTGACCTCTACGGCTGCACAAAGGATGTATACACTGTACGCAAtgctggtcttctgctgctgggCTATAAGAAAGACATCCAACCGAAATGACCCGAGCAGGCCTCAGTTGATCGATTGTTGGGTAACTAATGAATAAACTGTGCAAAAAGAGCTTGATTCCACTGGCTGAAGCGCTTACTCTCAATTTGCATCTCAACCAATCACCAATCATGTGACAGGTGCACATATAAACCAAGAGATTTGATTAGCAAAGGAGTTCTGGGATGTTTCCGTAGCCGCATGTCAGAACGAACAATGACCGTTGGCGGAAATAAAATGGATAGTGGCTCAGCCGTTTCTGCAGGTGCTTTCACAGAAGTGATTGACCGATAAGCGTCTGCATGAAAGAAAGCAGGAGACTCCCTGTGGAGCACACTCTGAAAGACAAAACCACTTACATAACCAAAATAATGCCACGGTGCCCAAGCAAGCCCATCTAGAGGAGAGATACGATTGTGTTTCAGACGCTCTTTAACCTCTAATGTAGGTCACCTGTTGTTGAGGAGCACAGAACTCCTTTCTTCAGCTGGCTGAATCGGTGGAGGATTGATGTCACAATCATGTCGGGAGCAATTCAGACTCAAAgtgaacaacaaaaaaagtctctcttgagagagaaagagagattcaGCAAGATGGACTGCGGAGATCCAAAGCCTGAAATTGCTACAAGTTGGGCAATGTTCAAAACAAGCTATGTTCGAGACATCCCTGTGGACCTCGCTTTCGTCTCTCGTTGTTTGTGTTGGGTTTGATCTTTCTGCATTGCCTTTAAGTGCCTTCAGGATtg
>TCONS_00060120
aGTGTTATACAGCGAATGGTGAGGACTACAGAGGTCGACAGAATCAGACCAGTCTGCAAGGAGGAAGGCCGTGCCTTTTCTGGAATGAAACATTCGAACGTCCATATAACACCAACAAATACCCCAATGGAGAAGGAGGGCTTGGGCAACACAACTTCTGCAGGAACCCAGATGGAGATGTCCGTCCCTGGTGTTACATTGCAGATCTCGAGGACGGATCTTACTGGAAATACTGCGATATCCCCACCTGCCAAATGCCAGGTAACCTGGGCTGTTTTAAGGACAGCGGTGATCCGACACCTTTATCTGGAAGCCACCAAACCTCCACCAAACTGACCATTCAGAACTGCATCAGCTTCTGCCGCAACCAAAGATACAAGCTTGCCGGGATGGAATCAGGCTATGCTTGCTTCTGCGGCGATGACCGTGAATATCACCGTCACGGTGATGCTCCGAACACAGAGTGTAACCATGTGTGTTTTGGAGATCACACTCAGCCGTGTGGAGGAGATGGACGCATCATCGTCTTTGACACAAAAGTAGGTGCTTGTGGAGGAAACTTCACATCACCTTCAGCAGTGATCTACTCTCCCGACTTCCCAGGCAAATACAGGTCTGGCAGTGTCTGCTACTGGACCATTCAGGTTCCAGGTTCTTCTGTTATTCTGTTCAACTTTACTTTCTTCAGTATCGTGGACCAAAAAGACATGGTGGAGCTGTTGGATGGTAAAACCAACCAGGTTGTGGCACGATTTGACGGCCGCAATCCTCCACGGGACATCGTGAATATCACCGCAGACTttgtcattttgtatttttactcCGATAGGACAAATGAGGCACTGGGGTTTTCTGTTGTTTATCATG
>TCONS_00060121
aGTGTTATACAGCGAATGGTGAGGACTACAGAGGTCGACAGAATCAGACCAGTCTGCAAGGAGGAAGGCCGTGCCTTTTCTGGAATGAAACATTCGAACGTCCATATAACACCAACAAATACCCCAATGGAGAAGGAGGGCTTGGGCAACACAACTTCTGCAGGAACCCAGATGGAGATGTCCGTCCCTGGTGTTACATTGCAGATCTCGAGGACGGATCTTACTGGAAATACTGCGATATCCCCACCTGCCAAAGTAAGTGTTTGAAAGGGGAAAACAGTACAGAGAAACCGAAATGAACAACGAGAGCAAGCTAAAGAAGAAACTAGGCCAAAAAAACTTGAAGTTCCCATCATCTGGATTATAAATCTGATATGCATAACCGCATTTTTGGAAAGGATTTTAATTGCTCCATCAGAAATCAGAATGTCCCAGCATGCACAGATACGTTCGTGGTGCTTGTCATCACTTGATGCTTTTTTACGTTCTCAACACTGAGCGTACACAAGCATCTGTGTTTGTATTCAAACTTTGGGTTTCCTTTTAAAGTGCTCTGATTGATCATTGATGATTCTAAACCTGCATTCACTATTGTTTCACATAATCAGCGCagacaaatttctttttttttttctcctttggtATTAGTGCATATGTCTATCCGTGCATGTCT

Function

symbol description
kremen1 Predicted to enable metal ion binding activity and transferase activity. Acts upstream of or within angiogenesis; lateral line development; and liver development. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in lens; midbrain hindbrain boundary; otic vesicle; posterior lateral line primordium; and ventral fin fold. Human ortholog(s) of this gene implicated in ectodermal dysplasia 13. Orthologous to several human genes including KREMEN1 (kringle containing transmembrane protein 1).

GO:

id name namespace
GO:0001525 angiogenesis biological_process
GO:0048884 neuromast development biological_process
GO:0048903 anterior lateral line neuromast hair cell differentiation biological_process
GO:0001889 liver development biological_process
GO:0048916 posterior lateral line development biological_process
GO:0016055 Wnt signaling pathway biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016740 transferase activity molecular_function
GO:0046872 metal ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070705-262 Predicted to enable metal ion binding activity and transferase activity. Acts upstream of or within angiogenesis; lateral line development; and liver development. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in lens; midbrain hindbrain boundary; otic vesicle; posterior lateral line primordium; and ventral fin fold. Human ortholog(s) of this gene implicated in ectodermal dysplasia 13. Orthologous to several human genes including KREMEN1 (kringle containing transmembrane protein 1).

Ensembl:

ensembl_id ENSDARG00000062579

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00060119 False 2365 mRNA 0.48 10 16151944 16274058
TCONS_00060120 False 867 mRNA 0.49 6 16161015 16218777
TCONS_00060121 True 673 lncRNA 0.42 2 16198544 16218777

Neighbor

gene id symbol gene type direction distance location
XLOC_030924 coq5 coding downstream 12344 16128214 ~ 16139600 (-)
XLOC_030923 xbp1 coding downstream 203024 15944411 ~ 15948920 (-)
XLOC_030922 si:dkey-1k23.3 coding downstream 299991 15841523 ~ 15851953 (-)
XLOC_030921 NA coding downstream 334387 15813775 ~ 15817557 (-)
XLOC_030920 BX649391.1 coding downstream 417364 15734525 ~ 15734580 (-)
XLOC_030926 NA coding upstream 5182 16279240 ~ 16351306 (-)
XLOC_030927 NA coding upstream 78939 16352997 ~ 16356940 (-)
XLOC_030928 slc39a14 coding upstream 86151 16360209 ~ 16425781 (-)
XLOC_030929 piwil2 coding upstream 154353 16428411 ~ 16475682 (-)
XLOC_030930 CR450719.1 coding upstream 171291 16445349 ~ 16445465 (-)
XLOC_030915 NA non-coding downstream 841836 15307539 ~ 15310108 (-)
XLOC_030913 CR936518.1 non-coding downstream 936160 15186823 ~ 15215784 (-)
XLOC_030912 NA non-coding downstream 1151948 14999622 ~ 14999996 (-)
XLOC_030933 CR392021.1 non-coding upstream 624865 16898923 ~ 16899047 (-)
XLOC_030934 CR759970.1 non-coding upstream 766563 17040621 ~ 17041288 (-)

Expression


Co-expression Network