XLOC_030928 (slc39a14)


Basic Information

Item Value
gene id XLOC_030928
gene name slc39a14
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 16360209 ~ 16425781 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00060123
ggttatctCCACACAGTGTTTTACGTGTTTCTGTCATGACCCTGAGACGAGCCAGTGGCTGCAGACAGCTGACCTTGACCATTGGCCTGGCCCTGACTTTAGGCCTGCTGCAGTGGCCAATAGGAGATGTTCGAGGTCAGGATGGAGCGTCTCCTGCCCAAGTCCTTCAGGAGCTGCTGACGCGATACGGAGACAACGCAAGCATTTCCGTCCCTCAGCTCCGATCGCTCCTCGTCAGGTTAAACGGAGGGCAGAGCGAAGaccatgacagtaaaacacagcCCACCAGGACCAATGCGTCTAAGTGCTTGGCCGCAGACACCCTGGCAGTGTACGGGATGAGCGAACAGTCTCGTATAGACGAGCGAGGCCTGCAACAGATCTGCCCTACAATGATACAGCAGCTGGACTCACAAGCGTGCAAAACACAACCAAACCAAGAGTCTGAGAGCAGCCCTAGACCCACTGAAGCTGAGGTGTGGGGTTATGGTTTGCTGTGTGTGACAGTGATATCTCTGTGTTCACTGGTCGGGGCGAGTGTGGTTCCCTTCATGAGGAAAACCTTTTACAAGCGGTTGCTGCTGTACTTCATTGCCCTGGCCATTGGTACTCTGTACTCCAACGCCCTCTTTCAACTAATCCCAGAGGCCTTCGGGTTTGACCCCATGGAGGATTATTATGTGCCCAAGTCCGCAGTCGTGTTTGGAGGATTCTACCTGTTCTTCTTTACAGAGAAAATCCTGAAGATGATCTTGAAGCCAAAAGACACGGGAGGGCATGGCCATGGGCACAGTCACTTTCCTGCTGAACGCTATGCCAACTCTAATGGTGATTTGGAGGATGGTGTGATGGAGAAACTGCAGAACGGAGAGGCTGGAGGAGCAGCTTTACCCAGAGCAGAAGCAGACGGCAGAGGGGTTGGAGAAGACGACAAGATGCTGAGCACTGGACAAACTGTACAGGACACTCAGAGTTCAGGTGGTGGTGGAACGGGTGGCTGCTATTGGCTGAAGGGCAGGGCTTACTCTGACATCGGCACGCTGGCGTGGATGATCACTCTGAGCGATGGCCTTCATAATTTCATTGATGGTTTGGCCATTGGAGCCTCCTTCACTGCATCTGTATTTCAGGGCATCAGTACATCAGTGGCGATTCTCTGTGAAGAGTTTCCTCATGAGCTGGgtgattTTGTGATCCTGCTAAACGCTGGCATGAGCATCCAGCAGGCACTCTTCTTTAACTTCCTGTCAGCCTGCTGCTGTTATCTGGGCATGGGCTTTGGCATCCTGGCTGGAAACAACTTCTCTCCTAACTGGATCTTTGCTCTGGCCGGTGGCATGTTCCTCTACATTGCGCTGGCTGATATGTTTCCAGAGATGAACGAGGTCAGTCGTGAGGAAGAGGAGGCTGGAGGAAGTGGCTTTCTGCTCACTTTCGCCCTCCAGAATGCAGGGCTGCTTACAGGCTTTGCCATAATGCTTGTACTCACCATCTACTCTGGACAGATACAGCTTGGATAGCAGAGGACTGAATTACAAACTCAGACCCTGGGGGACTAGCTCAGCACCTGGACTAAAAATCTGAGACCTTCTGGGACCTCTAGACTTAAATATGAGTCAGCTGTGCTGGCTTGTTTTTAAATTGTTCACCCAACTGGACTAGATCATGACATTCAAATGTTATGGCCAAAGTTTGGGCTCCAAATAAACCCTGGACTGTTTGATTGAAGCTAGAACTGATCAATCTGTGATCTTTGATTTGTAGATTCATCCAGAACCCTGGATCTGTGGATGGGTGCTCCACCATTCATCTGGTTTAGGCCTTCTTTCATTCTTTTGCCTCAAAAGCTTTAGGACACAGTGATGTCCCTGTACTGTGTGGATTCAACCCCCCAATACATACATCTGGGCATCGATTTCTTCTCAcaattcaactctgaaaactttaCAAATTGTCTCTTTCCTTCAGAGTTGAGGATTCTTATTCCTGACCTTGAAGATTTCAGTATTGTCCATTTACTGACATGTGATGGGATGAAACTTGACTTGTTTTACTGACATTAAGGCAACACTAGATTGTTTTCAATGCTTTAAACCAAATGATTAATCGGATCAATAGAGAAATAAAACCAACAGAACCAAGA
>TCONS_00060125
CGGTCACCTAATGAATATTCATTAACTGTATTTTACCGCCTTCCAATGGCGATGAATTATGCTTCTGAATATTAAGCGGCGCTTGCTGATGACGCCATATCTCCGCCCTGCGTGCTAGTTCCACGCTGCTGTCTTGTGAATGGGtcaagactgtaaaaaaaaaaaaaaacaaatccatcCGGTCTCTCTTTTTAAAACGGGTTACCCCATGTCCCTCAGATCATTCGTGAACGTCAGATAACGGACTACGCGCCTACAGATCAAGACATCTCAGATTTCGTGTTTTACGTGTTTCTGTCATGACCCTGAGACGAGCCAGTGGCTGCAGACAGCTGACCTTGACCATTGGCCTGGCCCTGACTTTAGGCCTGCTGCAGTGGCCAATAGGAGATGTTCGAGGTCAGGATGGAGCGTCTCCTGCCCAAGTCCTTCAGGAGCTGCTGACGCGATACGGAGACAACGCAAGCATTTCCGTCCCTCAGCTCCGATCGCTCCTCGTCAGGTTAAACGGAGGGCAGAGCGAAGaccatgacagtaaaacacagcCCACCAGGACCAATGCGTCTAAGTGCTTGGCCGCAGACACCCTGGCAGTGTACGGGATGAGCGAACAGTCTCGTATAGACGAGCGAGGCCTGCAACAGATCTGCCCTACAATGATACAGCAGCTGGACTCACAAGCGTGCAAAACACAACCAAACCAAGAGTCTGAGAGCAGCCCTAGACCCACTGAAGCTGAGGTGTGGGGTTATGGTTTGCTGTGTGTGACAGTGATATCTCTGTGTTCACTGGTCGGGGCGAGTGTGGTTCCCTTCATGAGGAAAACCTTTTACAAGCGGTTGCTGCTGTACTTCATTGCCCTGGCCATTGGTACTCTGTACTCCAACGCCCTCTTTCAACTAATCCCAGAGGCCTTCGGGTTTGACCCCATGGAGGATTATTATGTGCCCAAGTCCGCAGTCGTGTTTGGAGGATTCTACCTGTTCTTCTTTACAGAGAAAATCCTGAAGATGATCTTGAAGCCAAAAGACACGGGAGGGCATGGCCATGGGCACAGTCACTTTCCTGCTGAACGCTATGCCAACTCTAATGGTGATTTGGAGGATGGTGTGATGGAGAAACTGCAGAACGGAGAGGCTGGAGGAGCAGCTTTACCCAGAGCAGAAGCAGACGGCAGAGGGGTTGGAGAAGACGACAAGATGCTGAGCACTGGACAAACTGTACAGGACACTCAGAGTTCAGGTGGTGGTGGAACGGGTGGCTGCTATTGGCTGAAGGGCAGGGCTTACTCTGACATCGGCACGCTGGCGTGGATGATCACTCTGAGCGATGGCCTTCATAATTTCATTGATGGTTTGGCCATTGGAGCCTCCTTCACTGCATCTGTATTTCAGGGCATCAGTACATCAGTGGCGATTCTCTGTGAAGAGTTTCCTCATGAGCTGGgtgattTTGTGATCCTGCTAAACGCTGGCATGAGCATCCAGCAGGCACTCTTCTTTAACTTCCTGTCAGCCTGCTGCTGTTATCTGGGCATGGGCTTTGGCATCCTGGCTGGAAACAACTTCTCTCCTAACTGGATCTTTGCTCTGGCCGGTGGCATGTTCCTCTACATTGCGCTGGCTGATATGTTTCCAGAGATGAACGAGGTCAGTCGTGAGGAAGAGGAGGCTGGAGGAAGTGGCTTTCTGCTCACTTTCGCCCTCCAGAATGCAGGGCTGCTTACAGGCTTTGCCATAATGCTTGTACTCACCATCTACTCTGGACAGATACAGCTTGGATAG
>TCONS_00060124
CGGTCACCTAATGAATATTCATTAACTGTATTTTACCGCCTTCCAATGGCGATGAATTATGCTTCTGAATATTAAGCGGCGCTTGCTGATGACGCCATATCTCCGCCCTGCGTGCTAGTTCCACGCTGCTGTCTTGTGAATGGGtcaagactgtaaaaaaaaaaaaaaacaaatccatcCGGTCTCTCTTTTTAAAACGGGTTACCCCATGTCCCTCAGATCATTCGTGAACGTCAGATAACGGACTACGCGCCTACAGATCAAGACATCTCAGATTTCGTGTTTTACGTGTTTCTGTCATGACCCTGAGACGAGCCAGTGGCTGCAGACAGCTGACCTTGACCATTGGCCTGGCCCTGACTTTAGGCCTGCTGCAGTGGCCAATAGGAGATGTTCGAGGTCAGGATGGAGCGTCTCCTGCCCAAGTCCTTCAGGAGCTGCTGACGCGATACGGAGACAACGCAAGCATTTCCGTCCCTCAGCTCCGATCGCTCCTCGTCAGGTTAAACGGAGGGCAGAGCGAAGaccatgacagtaaaacacagcCCACCAGGACCAATGCGTCTAAGTGCTTGGCCGCAGACACCCTGGCAGTGTACGGGATGAGCGAACAGTCTCGTATAGACGAGCGAGGCCTGCAACAGATCTGCCCTACAATGATACAGCAGCTGGACTCACAAGCGTGCAAAACACAACCAAACCAAGAGTCTGAGAGCAGCCCTAGACCCACTGAAGCTGAGGtgTGGGGTTACTCAATTTTGAGCGTGACTCTGGTTAGTGCGTTCGCTTTGACTGGTGTGTTTGTGGTGCCCCTGATGAGGACGCGGTTCATGCGCAGAGTTCTGGTCTATTTCATCGCTCTGTCCATTGGAACATTGTTGTCCACCGCCATCCTGCAGCTCCTGCCTGAGGCCTTCGGGTTTGACCCCATGGAGGATTATTATGTGCCCAAGTCCGCAGTCGTGTTTGGAGGATTCTACCTGTTCTTCTTTACAGAGAAAATCCTGAAGATGATCTTGAAGCCAAAAGACACGGGAGGGCATGGCCATGGGCACAGTCACTTTCCTGCTGAACGCTATGCCAACTCTAATGGTGATTTGGAGGATGGTGTGATGGAGAAACTGCAGAACGGAGAGGCTGGAGGAGCAGCTTTACCCAGAGCAGAAGCAGACGGCAGAGGGGTTGGAGAAGACGACAAGATGCTGAGCACTGGACAAACTGTACAGGACACTCAGAGTTCAGGTGGTGGTGGAACGGGTGGCTGCTATTGGCTGAAGGGCAGGGCTTACTCTGACATCGGCACGCTGGCGTGGATGATCACTCTGAGCGATGGCCTTCATAATTTCATTGATGGTTTGGCCATTGGAGCCTCCTTCACTGCATCTGTATTTCAGGGCATCAGTACATCAGTGGCGATTCTCTGTGAAGAGTTTCCTCATGAGCTGGgtgattTTGTGATCCTGCTAAACGCTGGCATGAGCATCCAGCAGGCACTCTTCTTTAACTTCCTGTCAGCCTGCTGCTGTTATCTGGGCATGGGCTTTGGCATCCTGGCTGGAAACAACTTCTCTCCTAACTGGATCTTTGCTCTGGCCGGTGGCATGTTCCTCTACATTGCGCTGGCTGATATGTTTCCAGAGATGAACGAGGTCAGTCGTGAGGAAGAGGAGGCTGGAGGAAGTGGCTTTCTGCTCACTTTCGCCCTCCAGAATGCAGGGCTGCTTACAGGCTTTGCCATAATGCTTGTACTCACCATCTACTCTGGACAGATACAGCTTGGATAG

Function

symbol description
slc39a14 Predicted to enable anion:cation symporter activity and transition metal ion transmembrane transporter activity. Acts upstream of or within manganese ion homeostasis. Located in plasma membrane. Is expressed in neurogenic placode; notochord; presumptive telencephalon; pronephric duct; and somite. Human ortholog(s) of this gene implicated in hypermanganesemia with dystonia 2. Orthologous to human SLC39A14 (solute carrier family 39 member 14).

GO:

id name namespace
GO:0006882 cellular zinc ion homeostasis biological_process
GO:0032869 cellular response to insulin stimulus biological_process
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway biological_process
GO:0071578 zinc ion import across plasma membrane biological_process
GO:0071333 cellular response to glucose stimulus biological_process
GO:0034755 iron ion transmembrane transport biological_process
GO:0033212 iron import into cell biological_process
GO:0055071 manganese ion homeostasis biological_process
GO:0055085 transmembrane transport biological_process
GO:0030001 metal ion transport biological_process
GO:0006811 ion transport biological_process
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity biological_process
GO:0006829 zinc ion transport biological_process
GO:0005764 lysosome cellular_component
GO:0005765 lysosomal membrane cellular_component
GO:0005768 endosome cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0031901 early endosome membrane cellular_component
GO:0031902 late endosome membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016323 basolateral plasma membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016324 apical plasma membrane cellular_component
GO:0046873 metal ion transmembrane transporter activity molecular_function
GO:0015296 anion molecular_function
GO:0015086 cadmium ion transmembrane transporter activity molecular_function
GO:0005381 iron ion transmembrane transporter activity molecular_function
GO:0005384 manganese ion transmembrane transporter activity molecular_function
GO:0005385 zinc ion transmembrane transporter activity molecular_function

KEGG:

id description
ko04216 Ferroptosis
ko05010 Alzheimer disease
ko05012 Parkinson disease
ko02000 Transporters

ZFIN:

id description
ZDB-GENE-060315-2 Predicted to enable anion:cation symporter activity and transition metal ion transmembrane transporter activity. Acts upstream of or within manganese ion homeostasis. Located in plasma membrane. Is expressed in neurogenic placode; notochord; presumptive telencephalon; pronephric duct; and somite. Human ortholog(s) of this gene implicated in hypermanganesemia with dystonia 2. Orthologous to human SLC39A14 (solute carrier family 39 member 14).

Ensembl:

ensembl_id ENSDARG00000102387

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00060123 False 2143 mRNA 0.49 8 16360209 16405651
TCONS_00060125 False 1784 mRNA 0.51 9 16360832 16425781
TCONS_00060124 True 1784 mRNA 0.52 9 16360832 16425781

Neighbor

gene id symbol gene type direction distance location
XLOC_030927 NA coding downstream 3269 16352997 ~ 16356940 (-)
XLOC_030926 NA coding downstream 8903 16279240 ~ 16351306 (-)
XLOC_030925 kremen1 coding downstream 86151 16151944 ~ 16274058 (-)
XLOC_030924 coq5 coding downstream 220609 16128214 ~ 16139600 (-)
XLOC_030923 xbp1 coding downstream 411289 15944411 ~ 15948920 (-)
XLOC_030929 piwil2 coding upstream 2630 16428411 ~ 16475682 (-)
XLOC_030930 CR450719.1 coding upstream 19568 16445349 ~ 16445465 (-)
XLOC_030931 atad1a coding upstream 251483 16677264 ~ 16791223 (-)
XLOC_030932 galnt9 coding upstream 371428 16797209 ~ 16996482 (-)
XLOC_030933 CR392021.1 coding upstream 473142 16898923 ~ 16899047 (-)
XLOC_030921 NA non-coding downstream 542652 15813775 ~ 15817557 (-)
XLOC_030920 BX649391.1 non-coding downstream 625629 15734525 ~ 15734580 (-)
XLOC_030915 NA non-coding downstream 1050101 15307539 ~ 15310108 (-)
XLOC_030934 CR759970.1 non-coding upstream 614840 17040621 ~ 17041288 (-)
XLOC_030939 NA non-coding upstream 1863029 18288810 ~ 18289576 (-)
XLOC_030940 NA non-coding upstream 1892122 18317903 ~ 18424637 (-)

Expression


Co-expression Network