XLOC_031002 (glra4b)



Basic Information


Item Value
gene id XLOC_031002
gene name glra4b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 22515347 ~ 22544151 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00060228
GCTGTGCTCAGTCAGATGGCAGTGGAGGAGAGACCAGAGTGCATCAGAATGGGCGTCCTGCCCCTCAAAAACACATCTGCTCATTGAGATTTAGCCACGGGACACCAGAAAAGCAGCTGCTGAACAGTGAAAGGATGTTTTCTGTGATCTGGAGGATCCTACTGGAGCTCTTACTGGTTTGCTGGATGTTTGAAGGGGTCATCAGGTGTGTGTTTAGTAAGGAGCTGAAATCTCCCAGTGTTAGGACGAAGCCCATGTCACCATCAGATTTTCTGGATAAATTAATGGGAAAGACATCTGGATATGATGCTCGAATAAGGCCCAACTTTAAAGGTCCTCCTGTAAATGTCACCTGCAACATTTTCATCAACAGCTTTGGCTCGATCACAGAGACTACCATGGATTACCGGCTGAACGTTTTTCTACGGCAGCAGTGGAATGACCCACGACTAGCTTATAAAGAATACCCAGACGATTCCCTGGATCTGGACCCATCCATGCTGGACTCcatctggaagccagacttgttCTTCGCCAATGAGAAAGGCGCCAACTTTCATGAGGTCACCACAGACAACAAGCTGCTGAGAATTTTCCAGAACGGAAACGTGCTGTATAGCATCAGACTCACGCTGATTCTGTCGTGTCCTATGGATCTGAAGAATTTCCCAATGGACACTCAGACCTGCACTATGCAGTTAGAGAGCTTTGGCTACACTATGAATGATCTGATATTTCAGTGGTTGGACGAAGGCCCGGTGCAAGTAGCTGATGACCTTATGCTGCCCCAGTTTGTCCTCAAAGAAGAGAAAGACTTGGGATACTGTACAAAGCACTACAACACTGGTAAGTTCACCTGTATAGAGGTGAAGTTTCATCTGGAGAGGCAGATGGGTTATTACCTGATCCAGATGTACATTCCCAGCCTTTTAACAGTGATCCTGTCATGGGTCTCTTTCTGGATCAACATGGATGCCGCCCCGGCCCGAGTCGGGCTGGGCATCACCACAGTTCTTACCATGACCACACAGAGCTCAGGTTCTAGAGCATCACTGCCTAAGGTGTCCTATGTGAAGGCCATTGACATCTGGATGGCAGTGTGTCTGCTGTTCGTGTTTGCTGCTTTGTTGGAGTACGCAGCGGTTAACTTCGTTTCAAGGCAATATAAAGAATTCTTCCGACTGAGGAGGAAACTGCGGCAGGAGCAACGCAACAGAGCTGCCTCTGGTCAAGCTGGAGCAGCAGAAACGAAGAACAAGAGTAACAACGTCACAGGAGGCACACCGAGCAGAAACGCACAACGCCAGTGCAGCGCCTGCGCACGGGAAGAGCAGTTGGCCTCACAGAATCAGGACTTGTACTTTCCGGGCTTTGGGATAGACACGAGTCTGTCTGGAGACGGGCCTCTCTCTGAAGCTGCTGCCATGTTTGCTGGTTTGCCACCCGGTCATGCCCTGTTTGACATTCGCCGGCGCTTTGTGGAACAAGCGAAACGGATCGACACCATCTCACGAGCCGTCTTCCCCCTCAGCTTCCTCGTATTCAACGTGTTTTACTGGGTCACTTATAAAGTGCTTCGAAACGAAGACATTCACCTTGCACTGCGACCCTGACACCCTTTAGGACTTCTGAACTTCCCGTTATACCTTCTTGTGAACCAGTTTTGGTCCAGCGTGAGGATGAGCTCCTTTATCAAAGACATTTATAAAATCAAACCAGTCTATGAAGCGGTGCAACAAGTTCTCTCTGCATGAGTGAGAATATATGCATGAGTCTGAGAGCACTTTAACAAAGAGCTAAATAAACCTTTAGCTTATATGAAGAACGGCTGATTCACTCCTGACCTttgctctttttttgtttttgcacagaGCACATTTGTTCTTGTccgttgtaaaaaaaaataaatgttatatatgaATTTTC

Function


symbol description
glra4b Enables extracellularly glycine-gated ion channel activity. Predicted to be involved in several processes, including chloride transmembrane transport; glycinergic synaptic transmission; and neuropeptide signaling pathway. Predicted to act upstream of or within chloride transport. Predicted to be located in cell projection and postsynaptic membrane. Predicted to be integral component of membrane. Predicted to be part of chloride channel complex. Predicted to be active in neuron projection and synapse. Predicted to be integral component of plasma membrane. Is expressed in brain; hindbrain; retinal ganglion cell layer; retinal inner nuclear layer; and spinal cord. Orthologous to human GLRA4 (glycine receptor alpha 4 (pseudogene)).

GO:

id name namespace
GO:0042391 regulation of membrane potential biological_process
GO:0050877 nervous system process biological_process
GO:0007218 neuropeptide signaling pathway biological_process
GO:0034220 ion transmembrane transport biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:1902476 chloride transmembrane transport biological_process
GO:0060012 synaptic transmission, glycinergic biological_process
GO:0006811 ion transport biological_process
GO:0043200 response to amino acid biological_process
GO:0007165 signal transduction biological_process
GO:0043005 neuron projection cellular_component
GO:0045202 synapse cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0022824 transmitter-gated ion channel activity molecular_function
GO:0004888 transmembrane signaling receptor activity molecular_function
GO:0005216 ion channel activity molecular_function
GO:0005230 extracellular ligand-gated ion channel activity molecular_function
GO:0005254 chloride channel activity molecular_function
GO:0016594 glycine binding molecular_function
GO:0030594 neurotransmitter receptor activity molecular_function
GO:0016933 extracellularly glycine-gated ion channel activity molecular_function
GO:0016934 extracellularly glycine-gated chloride channel activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-020402-2 Enables extracellularly glycine-gated ion channel activity. Predicted to be involved in several processes, including chloride transmembrane transport; glycinergic synaptic transmission; and neuropeptide signaling pathway. Predicted to act upstream of or within chloride transport. Predicted to be located in cell projection and postsynaptic membrane. Predicted to be integral component of membrane. Predicted to be part of chloride channel complex. Predicted to be active in neuron projection and synapse. Predicted to be integral component of plasma membrane. Is expressed in brain; hindbrain; retinal ganglion cell layer; retinal inner nuclear layer; and spinal cord. Orthologous to human GLRA4 (glycine receptor alpha 4 (pseudogene)).

Ensembl:

ensembl_id ENSDARG00000058103

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00060228 True 1926 mRNA 0.48 10 22515347 22544151

Neighbor


gene id symbol gene type direction distance location
XLOC_031001 NA coding downstream 5283 22506445 ~ 22510064 (-)
XLOC_031000 sptbn4a coding downstream 13684 22465086 ~ 22501663 (-)
XLOC_030999 NA coding downstream 58058 22455566 ~ 22457289 (-)
XLOC_030998 NA coding downstream 59353 22453830 ~ 22455994 (-)
XLOC_030997 BX546499.2 coding downstream 76752 22435786 ~ 22438595 (-)
XLOC_031003 aifm1 coding upstream 6463 22550614 ~ 22573673 (-)
XLOC_031004 casp22 coding upstream 41118 22585269 ~ 22602979 (-)
XLOC_031005 zgc:113208 coding upstream 61379 22605530 ~ 22621417 (-)
XLOC_031006 apool coding upstream 307706 22851857 ~ 22868650 (-)
XLOC_031007 si:ch211-26b3.4 coding upstream 327567 22871718 ~ 22952156 (-)
XLOC_030995 NA non-coding downstream 280189 22230690 ~ 22235158 (-)
XLOC_031008 NA non-coding upstream 412744 22956895 ~ 22974641 (-)
XLOC_031012 BX640521.1 non-coding upstream 678550 23222701 ~ 23222819 (-)
XLOC_031015 CT025748.1 non-coding upstream 787002 23331153 ~ 23341623 (-)
XLOC_031017 NA non-coding upstream 902093 23446244 ~ 23456234 (-)
XLOC_031029 BX957257.2 non-coding upstream 1213782 23757933 ~ 23758587 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000339_01327907_01343305 GLRA3, GLRA4A, GLRA4B, GLRA4 coding CI01000339 null 1327717 ~ 1344940 (-)
bowfin (Amia calva) AMCG00014207 LOC108443135,LOC102799111 coding CM030128.1 CM030128.1 4460775 ~ 4498956 (+)