XLOC_003111 (raf1b)


Basic Information

Item Value
gene id XLOC_003111
gene name raf1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 506465 ~ 540252 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00006150
CTCAGTCGCGATAATCATGGCGGATCAACAATTCAACAACTTTCTCTGATCGGTGCCGTGAGCCGCTGTCCGCAGTGATGGAGCATTTTCAGGGGGCCTGGAAGAGCGTCAGCAGTCACGGCTTCGGGTGTAAAGACTCAGTATTCGAGGACTCCTGCATGTCTCCCAGCATCCTCAAGACCTTCCCGTACCGTAGATTATCCGACGATGGCAGAATCCCAGACTCCAAGACCAGCAGCACCATCCGCGTCTTCCTGCCCAACAAGCAGCGCACCGTGGTGAACGTGCGAGCAGGAATGACGCTGCGCAACTGTCTCATCAAAGCCCTGAAAGTTCGAGGTCTTCAGCCTGAATGCTGTGCTGTTTTCAAGCTTCAGCGGGAACATTCTGCTAAGAAGCTGCGCATGGACTGGAGCACTGATTCTACCTCACTGGTCGGAGAGGAGCTGCTGGTTGAAGTCTTAGATCACGTGCCATTGACCACGCACAATTTTGtacgcaaaacatttttgaagtTGGCCTTTTGTGACATCTGTCAGAAGTTTCTTTTGCACGGCTTCAGATGTCAGACGTGCGGATACAAGTTTCATGAGCACTGCAGCACCAAAGTGCCAACCATGTGTGTGGACTGGAGCAACATTCGCCAACTCCTGCTGTTCCCGACTCCTGGAGAGAACGGGGCTCTGACCCTCCCTCCGCTCTCGTCCCGTCGCATGCAAAACTCTAGATTCTCCTTCAGTCCCTATCACAGATACTCAACGCCAAATGCATTGAACTACATCACACCCCTGCCGTCCCCTGGAGTCTCTCTGGGCCATAAAGTCTTGTCCACATCCACACCCAATGTCCACATGGTGAGCACAACCCAGCCAGTCGATGAAGCTGCTTATCAGGAAGCCTTAAGGCATGATGAATCAGGAAGCCCTCAAAACTTAAGCCCGACCGAATGGTCCAAAACCCCAGCTCCGGCTCACAGGGAGAAAGCGCCTTCGAGTAACACTCAGGAAAAACGAATCCGTCCTCGAGAGAAGAGAGACTCCAGCTACTACTGGGAGATCGAGGCCACTGAGGTGCTTCTGCTCTCCCGGATCGGCTCAGGCTCTTTCGGCACAGTTTACAAAGGGAAATGGCACGGTGATGTTGCTGTGAAGATTTTAAAGGTCATCAATCCAACACCGGAGCAGTTGCAGGCCTTTCGCAATGAAGTGGCTGTTCTCAGGAAGACCAGGCATGTTAATATCGTCTTGTTTATGGGCTACATGACGAAGGTGAAGCTGGCCATCGTGACGCAGTGGTGTGAGGGAAGCAGCCTCTACAAACACCTGCATGTGCAGGAGACAAACTTCCAGATGTTCCAGCTGATGGACATCGCCAGACAGACGGCTCAGGGCATGGATTACCTGCATGCAAAGAACATCATCCACCGAGACATGAAGTCCAACAATATCTTCCTGCACGAGGGTCTGACGGTGAAGATTGGAGACTTCGGTTTGGCCACAGTAAAGGCTCGCTGGAGCGGCTCTCATAGAGTCGAGCAGCCGTCTGGATCCATTCTGTGGATGGCTCCTGAAGTGATCCGCATGCAGGATAATAACCCGTACAGCTTCCAGTCAGACGTGTACTCGTACGGGATCGTCCTGTATGAGCTGATGACCGGAGAACTGCCTTATTCTATGATTGGAAACAGAGATCAGatcatCTTTATGGTGGGTCGGGGTTATCTGTCTCCAGACCTCAGTAAGCTGTATAAGAGCTGTCCTAAAGCCATGAAGAGACTGGTGTCCGACTGCATCCAGAAGACCAAAGAGGAGCGCCCACTCTTCCCACAGATCTTGTCCTCTATCGAGCTCCTCCAGCATTCGCTCCCCAAGATAAACCGCAGCGCGTCTGAACCGTCGCTGCACAGAGCCACACACACCGAGGACATGAACGTCTGCACGCTGGCACTCACCTCTGCCTTTAAatgatggacacacacacacacacacacatacatatattcacactcataaatacataaacacacagtcagatacacatacacacacacattcacatacacactaataaaacacacacacacacacataggcattcTCACGCATAAACATTCACATAAAcagacacatttacacacacacacacatacatgcacaaacacatgcacacaaaacattcacaaaaacacacacacttacacacattgacataattcacatacacacactataacatacatgcgcacacacacacactcatccactggtttgtgtgtgtgtgtgtgtgtgtattgtcatGCTGATTTCTCTCTCCTTCACTGGACAGAGAAACACTAaagcactttctctctctctctctctctctctctctctctctttctctctctctctcctccgcCTCTGAGTCTGCTGGGAAACATCTGAGCCCCAGCTTAcaatcatgtgtgtgtatgtgtgtgtgtgtttatccgATCACGTCTCTGCGCTCTGcctctgtgtgtgtttcaggaactGCAGCAGAGGAGCGGGTATTAACTTTATTATCAGACTTACTAGGGTTTCTTTCTTTCTACTGGCTTGTTGTCGCCTGTCATGGAGAATTAACGTGTAAACAGATGGtttattcattgtattttaataaaattaagttaaacacacacacacacaca
>TCONS_00006151
CGGTTTGGCCACAGTAAAGGCTCGCTGGAGCGGCTCTCATAGAGTCGAGCAGCCGTCTGGATCCATTCTGTGGATGGCTCCTGAAGTGATCCGCATGCAGGATAATAACCCGTACAGCTTCCAGTCAGACGTGTACTCGTACGGGATCGTCCTGTATGAGCTGATGACCGGAGAACTGCCTTATTCTATGATTGGAAACAGAGATCAGatcatCTTTATGGTGGGTCGGGGTTATCTGTCTCCAGACCTCAGTAAGCTGTATAAGAGCTGTCCTAAAGCCATGAAGAGACTGGTGTCCGACTGCATCCAGAAGACCAAAGAGGAGCGCCCACTCTTCCCACAGATCTTGTCCTCTATCGAGCTCCTCCAGCATTCGCTCCCCAAGATAAACCGCAGCGCGTCTGAACCGTCGCTGCACAGAGCCACACACACCGAGGACATGAACGTCTGCACGCTGGCACTCACCTCTGCCTTTAAatgatggacacacacacacacacacacatacatatattcacactcataaatacataaaca

Function

symbol description
raf1b Predicted to enable protein kinase activity. Predicted to act upstream of or within intracellular signal transduction and protein phosphorylation. Predicted to be active in cytosol; mitochondrion; and plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 2; adenocarcinoma (multiple); and dilated cardiomyopathy 1NN. Orthologous to human RAF1 (Raf-1 proto-oncogene, serine/threonine kinase).

GO:

id name namespace
GO:0035556 intracellular signal transduction biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0007165 signal transduction biological_process
GO:0005829 cytosol cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005739 mitochondrion cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-090826-2 Predicted to enable protein kinase activity. Predicted to act upstream of or within intracellular signal transduction and protein phosphorylation. Predicted to be active in cytosol; mitochondrion; and plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 2; adenocarcinoma (multiple); and dilated cardiomyopathy 1NN. Orthologous to human RAF1 (Raf-1 proto-oncogene, serine/threonine kinase).

Ensembl:

ensembl_id ENSDARG00000059406

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00006150 False 2668 mRNA 0.49 17 506465 540252
TCONS_00006151 True 537 lncRNA 0.51 4 537022 539607

Neighbor

gene id symbol gene type direction distance location
XLOC_003109 NA coding upstream 1636 474380 ~ 504829 (+)
XLOC_003110 NA coding upstream 11932 489935 ~ 494533 (+)
XLOC_003108 rab43 coding upstream 56366 440305 ~ 450099 (+)
XLOC_003107 CR855375.1 coding upstream 135025 371322 ~ 371440 (+)
XLOC_003106 pdrg1 coding upstream 146148 355305 ~ 360317 (+)
XLOC_003112 NA coding downstream 3096 543348 ~ 544194 (+)
XLOC_003113 mkrn2os.1 coding downstream 35413 575665 ~ 580833 (+)
XLOC_003114 mkrn2os.2 coding downstream 42890 583142 ~ 589128 (+)
XLOC_003115 timp4.1 coding downstream 151482 691734 ~ 701305 (+)
XLOC_003116 timp4.2 coding downstream 165475 705727 ~ 711032 (+)
XLOC_003250 BX324177.11 misc downstream 10805551 11345803 ~ 11346099 (+)
XLOC_003255 BX324177.14 misc downstream 10832634 11372886 ~ 11373182 (+)
XLOC_003257 BX324177.13 misc downstream 10846110 11386362 ~ 11386658 (+)
XLOC_003260 BX324177.2 misc downstream 10877781 11418033 ~ 11418323 (+)
XLOC_003262 BX324177.15 misc downstream 10889141 11429393 ~ 11429689 (+)
XLOC_003104 NA non-coding upstream 207366 298450 ~ 299099 (+)
XLOC_003101 NA non-coding upstream 339641 96979 ~ 166824 (+)
XLOC_003118 FQ311892.1 non-coding downstream 190555 730807 ~ 730923 (+)
XLOC_003126 AL935272.1 non-coding downstream 1005865 1546117 ~ 1546231 (+)
XLOC_003132 NA non-coding downstream 1395432 1935684 ~ 1997410 (+)
XLOC_003133 NA non-coding downstream 1411379 1951631 ~ 1952594 (+)

Expression


Co-expression Network