XLOC_031908 (pnkd)


Basic Information

Item Value
gene id XLOC_031908
gene name pnkd
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 13024448 ~ 13037815 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00062478
ATCGCGTCATCGCCGCCCGCCTACTGTAATGGCGCTTCCGGAGTGGACcgtgtatttactgtgtattgCTTCAGTCTGTGGCGGATTTTACATTTGTAGAGTTGTTAAATGCGCCAGGAAAAGTGCGTGGAAAAACAGTCAGATCGCTAAGCTGATGGCTCGCTCAGAGAAACCGCTTTTTTGGATTGCgtACTCTCTGTATACACGGACCAAACTCGGGTACATATTTCACAAGAGGCAGATGAAAAAAGCACGGGAACGGTATCCCACTGGCCACTCCAGAGCTCAGCCGACTATAATAAATGGCATCAAGATCATACCGGTTCCCATCTTATTAGACAACTACAGCTATGTGGTTATCGACACTGCATCAAATACGGCTGTTGTGGTCGATCCCGCTGACCCTCAGCCTGTTCAGGCATGCCTAGAGGCAGAGGGGGTGGCTTTACAAGCTGTTCTCTGCACACATAAGCACTGGGACCACAGTGGAGGAAACAGGGCTTTAAAAAGACGCTACAGCTCCTGTCGAGTGTATGGGAACGCAATGGACAACATTCCAGGCCTCACACACCCCCTTTTAGACAAAGACACAATAGATTTTGGAACTCAACTACACTTCAGGGCCTTCTACACACCAGGACACACAGTGGGTCACATGATCTACTTGCTTGACGGCCGTGCGATCGGTGGTCCCAGCAGCCTGTTTTCAGGGGATCTGGTATTCCTCTCTGGATGCGGGAGAATGTTTGAGGGTAATGCCTCGACTATGCTGTCCTCTCTGGATACCGTGGGATCACTGAATGATGATACTCTGCTTTGGCCTGGACATGAATATGCTGAGGATAACCTGCTCTTTGCTGCTGACGTGGAGCCTGGCAATGTTGTTCGGGAGCAAAAACTGCAGTGGGTGCTGCAACAGAGGAGCCAGAGACTGTGTACATGTCCATCCACTCTTCTAGAGGAGAAGCAGTATAATCCGTTCCTGCGGAGTCATTCCCAGGATCTCCATCAGGCTCTGGGCCTGCAACAGAAGCAGGATGAGGACTGGACATCATATCGCGCCCGAGTTTTAGAGGAGCTGCGCAGGCGGAAAGACATTTACAAGGACCGATAAGATGTTTATCCCCTAAAATTTGGAGGATTTAACCAATGAAACCATTCCAACCCAAATGTATTGCTCCCTAAATACTGTGCCATCTAATAATATTGGCAGccttggtaaatatgagcaaagaGTAAAGGAATTAACCTCTACTCTCTAGACAAAATAGCTCAAAAGGGTTAAAAAGCCACTACTTTTATTGCAAAAatcttccttttttttcttttgaattaaATAGATTAGAGATTAAAAAATAagggaattttttacagtactcTTTTCTGATATTTACCAAGGGTGCTAATATTAGCGGAGGGCACTCTATATTAAGTGTGCTGGATTTAAAACACTAATGTGAATCTT
>TCONS_00062479
GCACGGGAACGGTATCCCACTGGCCACTCCAGAGCTCAGCCGACTATAATAAATGGCATCAAGATCATACCGGTTCCCATCTTATTAGACAACTACAGCTATGTGGTTATCGACACTGCATCAAATACGGCTGTTGTGGTCGATCCCGCTGACCCTCAGCCTGTTCAGGCATGCCTAGAGGCAGAGGGGGTGGCTTTACAAGCTGTTCTCTGCACACATAAGCACTGGGACCACAGTGGAGGAAACAGGGCTTTAAAAAGACGCTACAGCTCCTGTCGAGTGTATGGGAACGCAATGGACAACATTCCAGGCCTCACACAGTCAGTACCTGCTGTTCTGCCATCCCATCATGTATCATTTGAACTGTTCAAACGAATATTTTACATTGTTTAGATGCCATTCCATATTCTGCTctcacaaaataaacatttt

Function

symbol description
pnkd Predicted to enable hydroxyacylglutathione hydrolase activity and metal ion binding activity. Predicted to act upstream of or within methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in paroxysmal nonkinesigenic dyskinesia 1. Orthologous to human PNKD (PNKD metallo-beta-lactamase domain containing).

GO:

id name namespace
GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004416 hydroxyacylglutathione hydrolase activity molecular_function

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-050208-278 Predicted to enable hydroxyacylglutathione hydrolase activity and metal ion binding activity. Predicted to act upstream of or within methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in paroxysmal nonkinesigenic dyskinesia 1. Orthologous to human PNKD (PNKD metallo-beta-lactamase domain containing).

Ensembl:

ensembl_id ENSDARG00000071032

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00062478 False 1465 mRNA 0.46 9 13024448 13037815
TCONS_00062479 True 432 lncRNA 0.47 4 13027864 13031519

Neighbor

gene id symbol gene type direction distance location
XLOC_031907 si:ch73-71c20.5 coding upstream 30946 12986853 ~ 12993502 (+)
XLOC_031906 mcm6 coding upstream 39058 12968101 ~ 12985390 (+)
XLOC_031905 cxcr4a coding upstream 100721 12922002 ~ 12923727 (+)
XLOC_031904 fam117ba coding upstream 158621 12853655 ~ 12865827 (+)
XLOC_031903 stk24b coding upstream 473089 12482599 ~ 12551359 (+)
XLOC_031909 catip coding downstream 2136 13039951 ~ 13045541 (+)
XLOC_031910 casp8 coding downstream 8070 13045885 ~ 13058979 (+)
XLOC_031911 l3hypdh coding downstream 45331 13083146 ~ 13091856 (+)
XLOC_031912 dytn coding downstream 59097 13096912 ~ 13133917 (+)
XLOC_031913 CT009620.1 coding downstream 163543 13201358 ~ 13204969 (+)
XLOC_031897 AL929243.2 non-coding upstream 1249716 11774617 ~ 11774732 (+)
XLOC_031889 BX548046.3 non-coding upstream 2005916 11018416 ~ 11018532 (+)
XLOC_031888 NA non-coding upstream 2016018 10988645 ~ 11008430 (+)
XLOC_031887 NA non-coding upstream 2093358 10930890 ~ 10931090 (+)
XLOC_031885 NA non-coding upstream 2134224 10889061 ~ 10890224 (+)
XLOC_031915 NA non-coding downstream 222267 13260082 ~ 13267143 (+)
XLOC_031917 NA non-coding downstream 306860 13344675 ~ 13348236 (+)
XLOC_031925 dre-mir-153b non-coding downstream 943130 13980945 ~ 13981092 (+)
XLOC_031933 NA non-coding downstream 2267950 15305765 ~ 15308585 (+)
XLOC_031935 CR956630.1 non-coding downstream 2506240 15544055 ~ 15544170 (+)

Expression


Co-expression Network