XLOC_032893 (bcl6aa)


Basic Information

Item Value
gene id XLOC_032893
gene name bcl6aa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 28216487 ~ 28222592 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00063915
GCTCAAATTCCGAGAATTGAGCTCTTCTGATTCTTAGAACTGGGGTTCTTAGAAGTGGTGATGCAAGAAGTTTCTAGGAAAGCACTACCAGATCTAGAAAAAATGGCTTGTGCAGCCGACAGCTGCATCCAATTCACGCGTCATGCAAGTGATGTTCTGCTCAACCTGAACCGACTGCGTAGCAGAGATATCCTCACAGATGTCACGATTCTGGTCAACAGACAGCAGTTTCGAGCACACAAAACAGTCCTTATGGCATGCAGTGGGCTCTTCTACTCTATCTTTACCGATTCACACAAATGTAACCTGAACGCCATCAGTCTGGACCCGAAGGTCGACCCAGAGGGTTTCGCAATCCTTTTGGAGTTCATGTACACTTCACGTCTCGCACTGAAGGAGAGCCTCATCATGGCCATCATGAACACGGCCATCTACTTGCAGATGGACCACGTTGTTGACACGTGCCACAGATTCATAAAGTCCAGCGATTCCTCCATCAAACTTCCCAGAGAGGACTTTCTGGTCAGCCCCCTGCTTTTACCTCAAGACATTCACAGTTACAGACCCCATGAGGTTATGGATAATGTGTCAGGACGATCAGCAACTTTCAGAGACGGGAGACCCTATGGTGTCTGCATGTTTAATGGGGTCAATGCTCCTAACAACTCGTACCTTTATGGCCAGTTTCCCATGCAAGGCTTCCCCTTTCCTCTTTGCAAGCTGACAGACACTAAAAACACTTTCTCAGACTTCTCAAAGGGAGGCATCATTCATCACAAACACTGCTCGCCGAGTGACGGTAACAACCCAGTGCTGAATGACTTCACCCGCAGTGCTACCAGTGGGAGCTCAGCTGTTTGCCACACCGGGTCATACTCCTCCAGGGAGCTGGGAAGAGATGAAGATATGAAGAGGGAGACGTTGGAGGGCGTTGTCCATTCGATCGGGATGAGCTCCAGGAAGCACGGCTTCATTAGCCTGGCTCAGGAGCAGCAGAGGGAGAGTGGGAAAGAGCAGAGTTCCCTAGCAGAGGAACATTTGAGCCACCAACACTACTCCATGGGTATATCCTCTAATGGGCGCAAAACCTTGATGAGCAGCCCCCAGAGCCCCCTCAAATCAGACTGCCAGCCCAACTCTCCAACGGAATCAAGCAGCAGCAAAAATGCTGCTCTCGCACAGGCCTTGCAACCTCCAACTTCTCAAGGTACATCAGATCCTAAAGCTCGCAACTGGAAGAAATACAAGTTCATTGTGCTCAATCAGAGCTCCAAGGAGGAGGAGACCAATCCTCCTGACCCTGGAATGCACTCCCCACAGAGGCCGGGATTGTCTGCTTTCCTTCACCATGTTGACTCAGAACATCCTGACTCAAAAGTGACAACAAAGATTAGCGAGCAGGGCGAAGACTTCCCTGCGCCTCAGGCCAGTCGTCTCAACAACATCATCAACAGAAGTCTGGAGGGATCTCAGAGGAACATCGACAGCCACTCTTCTCTCTATATGAACCATTTGAAATGCTCATCCTGTGGCTCCCAGTCTCCACAGCACTCTGACGTCTGTCCCAACACATCCGCCTCGCGTCTGGCTGAGGAGATGTCCGAGATGCACTCCGAGTATTCTGATTCCAGTTGTGAAAATGGAACATACTTCTGTAATGAATGCGACTCCAAGTTTGCAGAGGAGGAAGCCTTGAAACGCCACACGCTTCAGGTCCACAGCGACAAGCCATACAAATGTGACCGTTGCCAAGCAGCATTCCGCTACAAGGGAAACCTTGCCAGTCACAAAACAGTTCACACCGGAGAGAAACCGTATAGATGCAATATCTGCGGGGCCCAGTTCAACAGACCCGCTAACCTCAAAACCCACACACGAATTCACTCAGGAGAAAAGCCATACAAGTGCGAGACATGCGGGGCTAGATTCGTGCAGGTTGCTCACCTTCGGGCTCATGTTCTGATTCATACCGGAGAGAAGCCATATCCATGCGAGATCTGTGGTACTCGTTTCCGCCATTTGCAGACGCTGAAAAGTCACCTGCGGATACACACAGGAGAAAAGCCCTATCATtgcgAGAAATGCAACTTGCATTTTCGCCACAAGAGTCAGCTGCGGTTACACCTCCGACAGAAACATGGTGCCATCACCAATACCAAGATCCAATATCGCATGTCCTCGACAGAACTACCAACCGACCTGACAAAGGCATGCTGAGCAGGCACTTATGGGAAGACCTGACCATGGCATTATATGACCTGACTTGTACAATCATTCAAAATTTTAGTGCCACACTGTGTCAATCGgacaagga

Function

symbol description
bcl6aa Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator and retina morphogenesis in camera-type eye. Predicted to be active in nucleus. Is expressed in brain; eye; and myotome. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Orthologous to human BCL6 (BCL6 transcription repressor).

GO:

id name namespace
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0060042 retina morphogenesis in camera-type eye biological_process
GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological_process
GO:0005634 nucleus cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1696 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator and retina morphogenesis in camera-type eye. Predicted to be active in nucleus. Is expressed in brain; eye; and myotome. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Orthologous to human BCL6 (BCL6 transcription repressor).

Ensembl:

ensembl_id ENSDARG00000070864

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00063915 True 2314 mRNA 0.50 9 28216487 28222592

Neighbor

gene id symbol gene type direction distance location
XLOC_032892 NA coding downstream 86357 28124381 ~ 28130130 (-)
XLOC_032891 si:ch73-194h10.3 coding downstream 98492 28115383 ~ 28117995 (-)
XLOC_032890 NA coding downstream 261886 27938489 ~ 27954601 (-)
XLOC_032889 im:7152348 coding downstream 324526 27884372 ~ 27891961 (-)
XLOC_032888 AL935299.1 coding downstream 489090 27696323 ~ 27727397 (-)
XLOC_032894 si:busm1-105l16.2 coding upstream 117070 28339662 ~ 28345002 (-)
XLOC_032895 tbc1d23 coding upstream 691641 28914233 ~ 28943056 (-)
XLOC_032896 tomm70a coding upstream 723449 28946041 ~ 28961660 (-)
XLOC_032897 glmnb coding upstream 747921 28970513 ~ 28980829 (-)
XLOC_032898 NA coding upstream 761425 28984017 ~ 28986397 (-)
XLOC_032887 NA non-coding downstream 592966 27620675 ~ 27623521 (-)
XLOC_032886 NA non-coding downstream 724740 27490737 ~ 27491747 (-)
XLOC_032881 NA non-coding downstream 1178116 27035652 ~ 27038371 (-)
XLOC_032908 NA non-coding upstream 1187634 29410226 ~ 29411285 (-)
XLOC_032910 NA non-coding upstream 1435309 29657901 ~ 29659956 (-)
XLOC_032911 NA non-coding upstream 1528368 29750960 ~ 29752357 (-)
XLOC_032912 NA non-coding upstream 1548775 29771367 ~ 29790125 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000340_02936853_02939837 BCL6A, BCL6 coding CI01000340 null 2935637 ~ 2939837 (-)
bowfin (Amia calva) AMCG00009217 NA coding CM030126.1 CM030126.1 29187536 ~ 29197143 (-)