XLOC_037504 (edar)


Basic Information

Item Value
gene id XLOC_037504
gene name edar
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 56103173 ~ 56172757 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00073717
CACCGGAATGATCTGAGCTGATCTGTTTTAATCTGATCTGATCTCCGGTCACTCTCTCCAGCTCGGTGTTTCACCTGTGAGTGTCCAGCAGCGCTCCGTCTCCCGCAGATCCTCAGCTGGAAGACGACACCATGGGTCATAAAGGAGGACGGACGCCATCTTTCCTCCTGCATTTTCTGCTGgtgtccAGCATGTCTACAGTGAGCGCTGAATACTCGAGCTGTGGAGAAAATGAGTTTTACAATCACACAACCAGCAGCTGCCAACCCTGCCCACAGTGCCAAGCTGGACAAGAGCCGTACATGAACTGTGGTTACGGCACTAAAGACGATGATTACTCCTGCGTTTCCTGTCCGGCTGGTAAATTCTCCAAAGGAAAGTACGAGATCTGCCGTCGACACAAAGACTGTGACGCTCTTTACCGCGCCACTGTCCTGACGCCCGGCACCTCTGACAGCGACGCTGAGTGCGGACACTGTTTACCAGGGTACTACATCCAGGAGAACCGGCCGCAGAACATCTACGGTATGGTGTGTCATTCATGCCAAAACGCTCCTCGAAACATCAAAGAGTGCATGAGGTCCACACCGCCAGCCTCAGGTCGAGCTCCCAGTGTTTCTTCCAGCAGCACCACTATATTCCCTCAGCCAGAGAAAGACCCAACAGGACAGGGTCACCTAGCAACGGCCCTCATCATCGCCATGTCAACCATCTTCATCATGGCCATCGCTATAGTGATGATCATCATGTTCTACATCCTGAAGAGCAAACCGAGCGGACCAGTCTGCTGTTCTGGTCAGCTCATCAAAGCTGTAGAAGCTCAGACAAACATGCAGGAGGAGAAGAAGGAGGCTCAGGAGAACGTGGTGATCTTTCAGGAGAAGGACGAATTTGACAAACTCAAGCCTTCATCTCCAAAAACAGCCAAAAGTGAGAATGACGCGTCATCAGAAAACGAGCAGCTGCTGAGTCGCAGTATCGACAGTGATGAAGAAGCAGCGCAGGACAAACAGGGAGCTGCAGATCTTTGTCTTCTTTCACTGGTGCATCTGACCAGAGACAAATCCTGCACCACCAAcaccatcaacaacaacaacaacaaccactgCAGCAGAGCCACCGGGATTCACAGCAGAAGGAAAAAGATCCTGGATTTGTACACAAAAGCCTGCAGTGTTGCGGAAGGTCTGAGCCCGACGGAGCTGCCGTTCGACTGTCTGGAGCGCAGCAGCCGGATGCTCAGCGCCACCTACAGCACAGATAAAGCGGTGGTGAAGACGTGGAGGCACCTGGCGGAGAGCTTCGGGCTGAAGAGAGACGAGATCGGCGGCATGACGGACGGGATGCAGCTGTTCGACCGCATCAGCACCGCTGGATACAGCATCCCTGACCTGCTGGCGCGCCTGCTGCAGATCGAGCGGCTGGACGCGGTGGAGACGCTCTGCTGCGACATCCTGAGCGGAACACAGAACTGCACTAATCCGCCCCTGAGCTCCCGCTGCGCCAGCGTCTGAA

Function

symbol description
edar Predicted to enable signaling receptor activity. Acts upstream of or within dermal bone morphogenesis and fin development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including epidermal cell; integument; mouth; pectoral fin skeleton; and pelvic fin bud. Human ortholog(s) of this gene implicated in ectodermal dysplasia 10A and ectodermal dysplasia 10B. Orthologous to human EDAR (ectodysplasin A receptor).

GO:

id name namespace
GO:0060348 bone development biological_process
GO:0061972 dermal bone morphogenesis biological_process
GO:0046330 positive regulation of JNK cascade biological_process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0033333 fin development biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0038023 signaling receptor activity molecular_function

KEGG:

id description
ko04064 NF-kappa B signaling pathway
ko04060 Cytokine-cytokine receptor interaction
ko04050 Cytokine receptors

ZFIN:

id description
ZDB-GENE-070117-2062 Predicted to enable signaling receptor activity. Acts upstream of or within dermal bone morphogenesis and fin development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including epidermal cell; integument; mouth; pectoral fin skeleton; and pelvic fin bud. Human ortholog(s) of this gene implicated in ectodermal dysplasia 10A and ectodermal dysplasia 10B. Orthologous to human EDAR (ectodysplasin A receptor).

Ensembl:

ensembl_id ENSDARG00000099088

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00073717 True 1515 mRNA 0.54 12 56103173 56172757

Neighbor

gene id symbol gene type direction distance location
XLOC_037503 CR352223.1 coding upstream 186629 55916413 ~ 55916544 (+)
XLOC_037501 NA coding upstream 196183 55900719 ~ 55906990 (+)
XLOC_037502 NA coding upstream 198223 55902859 ~ 55904950 (+)
XLOC_037500 NA coding upstream 215834 55880829 ~ 55887339 (+)
XLOC_037499 sept10 coding upstream 228096 55857193 ~ 55875077 (+)
XLOC_037505 TBC1D8 coding downstream 21653 56194410 ~ 56222014 (+)
XLOC_037506 cnot11 coding downstream 59791 56232548 ~ 56245149 (+)
XLOC_037507 NA coding downstream 149217 56321974 ~ 56323914 (+)
XLOC_037508 gpr39 coding downstream 249554 56422311 ~ 56426047 (+)
XLOC_037509 CABZ01079480.1 coding downstream 270659 56443416 ~ 56459826 (+)
XLOC_037498 FP236644.1 non-coding upstream 404550 55666315 ~ 55698623 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00014237 NA coding CM030128.1 CM030128.1 6033437 ~ 6054435 (+)