XLOC_038035 (adcy5)



Basic Information


Item Value
gene id XLOC_038035
gene name adcy5
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 37872577 ~ 38021997 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00074613
TCCTACCCCTTTCGATCCTCTTTCTTGCGTGTTAAAATCTTCATTAGGAAGTGAAACCCTGCGTAATTCGCACCCTGCGTTCATTTGCTGTATGTGATAATCGAGATCATGTCCAGATCTAACAGCGTGAGCCCACCCGGCGCTGGCGCTCCTGGACTGAGGGGAGGGACGGAGCACAGATCCGCTTGGGGCGAGTCTGAGTCCGTGGCGAACGGATGTCCATACTCGGCCAGATCCTCCTGCAAAAAGCTCATACGGTCCAACAGTCGCTGGAGAGAGGACGATGACTTCGAGCGACAACCGGGCCGAGCCACGACCACCGTCAGCCGGGTTAGCTTCAGATCCAAGTCCGCCTGGCAGGAACAAGGCGAGGAGAGCCGCAACAACAACCGATCGTCCCCGAGGTACCGAGATGGAGAAGTGAGACCCAAATCCGTGGAGCTGGGTCTGGAGGACAGGAGAACCAAGTCCAAACCAGAGGAGGAGCTCATGCCTGAAGTGAACTTTTCCATGAGCGCGTGCTGCAACAGCGTGATGCAGATTTTCAGGTCCAAGAAGTTCCAGTCGGAGAAGTTGGAGAGACTCTACCAGCGCTACTTCTTCCGCCTGAACCAGAGCAGCCTGACGATGCTGATGGCCGTGCTGGTGCTGGTGTGCGCGGTGATGCTGGGCTTCCACTGCGCCGGAGGGATGTGCCAGCTCACCTTCGTGCTGGTTTTCACCGCGGCGATCGTGCTCATCCTCACGCTGATGGTGGTGTGCAACAGGAACAGCTTCCATCAGGATCACATGTGGATAGTTTGTTATTTGCTGATTTTGCTGGTGCTGGCCGTGCAGGTAGTCGGCGTGCTGTTCGTCAAGCCGCGGAGCGCGTCTGAAGGCATCTGGTGGACCGTGTTTTTCATCCACGTCATTTACACGCTTCTGCCGGTGCGGATGAGAGCGGCGGTGATCACTGGGATTATATTGTCTGCCATTCATGTGCTCATCTCGTGGAGGTTAAACGACATGGACGTCTTCTTGTGGAAGCAGCTGGTGTCCAATGTCCTGATCTTCTCCTGCTCTAATATAGTTGGTGTGTGCACACACTACCCAGCAGAAGGTTCTCAGAGACAGGCCTTCCAGGAGACCAGAGAATGTATTCAAGCCCGTCTGCACTCGCAGAGAGAAAACCAGCAACAGGAGCGTCTCCTCCTCTCTGTGCTTCCTCGTCATGTGGCCTTGGAAATGAAAGCCGACATTAATGCCAAACAGGAGGATATGATGTTCCACAAAATCTACATTCAGAAGCATGACAATGTGAGTATCCTCTTTGCTGACATTGAGGGCTTCACCAGTCTGGCTTCCCAGTGCACTGCCCAGGAGTTAGTGATGACCCTCAACGAGCTTTTCGCACGATTCGACAAACTGGCCGCCGAGAATCACTGTCTGCGGATCAAGATTCTGGGTGACTGCTACTACTGTGTGTCAGGGCTGCCGGAGGCCCGTGCTGACCATGCGCACTGCTGTGTGGAGATGGGAGTGGACATGATAGAAGCAATCTCCTTGGTGAGGGAAGTCACCGGTGTGAACGTCAACATGCGTGTTGGAATACACAGCGGGCGCGTTCACTGCGGGGTGCTGGGATTAAGGAAATGGCAGTTTGATGTCTGGTCCAACGATGTCACCTTGGCCAACCACATGGAAGCTGGGGGCAAAGCAGGGCGTATACATATCACCAAGGCCACTCTAAACTACCTGAATGGGGATTATGATGTGGAACCTGGATCTGGTGGAGAAAGAAACGTGTATCTCAAGAAGCACAACATTGAAACCTACCTCATTGTGGGCTGCAGTCAGAAGCGGAAAGAAGAAAAGGCCATGATTGCTAAGATGAACCGACAGCGCACCAACTCGGTCACTCATAACAGCACTCACTGGACCGACCGGCCCTTCTATAATCACCTGAATGCCAATTCTGTTTCCAAGGAGATGAAGAGGATGGGATTTGAGGATCCCAAAGACAAAAACACGCAAGAGAACCTGAATCCAGAGGATGAGGTGGATGAGTTTCTGGGCCGCGCCATTGATGCTCGGAGCATCGACCGGTTAAGATCTGAACACGTCAAGAAATTTTTGCTGACCTTCAGAGAACCTGATCTGGAGAAGAAGTACTCTAAACAGGTGGATTCCAGTTTCGGTGCATATGTGGCCTGCGCCTCCCTCGTCTTTTTATTCATCTGCTTCATTCAGATCATCATTGTGCCGCATTCTGGACTGATGGTTGGTTTCTATGTGCTCTGTCTGGTCGTTCTGATGGTGGTCATGTTCATCTCAGCCATTTACTCCTGTTTTGGGTTTTTCCCCATTCCTCTGCAAACTCTGTCTAAAAGGATTGTTCAGTCCAGACTCAACAGCACCCTGGTGGGGGTTTTTACAATCGTCCTGGTCTTTATCTCTGCTTTCATTAACATTTTCACCTGCAGTACGGATGACCTGAAGACGTgtttagggcaggagtttaacatcAGCCCCAGCAATGTGAACGCTTGCCATGCCCATTTCTCTTCCCTCAACTACACACTCTGGTCTCAGAACAGGCTCTGCAACAGTTCGTCACCAACATGCAATTTCCCAGAGTACTTCTCATCATGTGTGCTGCTCAGTTTGCTGGCCTGCTCAGTTTTTCTACAGGTCAGCAGTATCGGTAAACTCTTCCTCATGCTCTTCATTGAGATCCTGTATGTGCTTATCATGGAGGTGCCCGAGGTCAGCCTTTTTGACAATGTGGACCTGCTGGTCATGGCCAATGCCCTAGCGCCTAACAATGGAACATGTATTGTGGACACCCGGGTTCCTCTAAAGATCGTGACTCCAGTGGTCATCACAGTCTTTGTGCTGGCGCTTTACCTTCATGCACAGCAGGTTGAGTCCACCGCCAGACTCGACTTTCTATGGAAGTTACAGgccacagaggaaaaggaggagatggaaGAACTTCAGGCTTACAATCGTCGGCTTCTTCACAACATCTTGCCCAAAGATGTGGCTGCACACTTTCTGGCCCGCGAGCGGAGGAATGACGAGCTGTACTACCAGTCGTGTGAATGTGTGGCTGTCATGTTTGCCTCCATCAGCAACTTTTCCGAGTTCTACGTGGAGTTGGAGGCCAATAATGAAGGTGTTGAATGCTTGAGACTTCTCAACGAGATCATCGCTGACTTTGACGAGATCATAAGTGAGGATCAGTTCCGTCAACTAGAAAAGATCAAAACCATTGGCAGCACCTACATGGCTGCATCTGGGCTTAATGACTCCACTTATGATAAAGCAGGAAGGTCACACATTCGCGCTCTAGCCGACTATGCCATGCGCCTCATGGACCAGATGAAGTACATCAATGAGCACTCTTTCAATAACTTCAAAATGAAGATCGGTCTCAACATGGGTCCTGTTGTGGCTGGAGTCATAGGAGCTCGTAAACCACAATATGACATATGGGGGAATACTGTGAATGTAGCCAGCCGTATGGACAGCACTGGGGTACCTGAGAGAATACAGgtCACAACGGACCTTTACCAGGTTCTCAGCTCCTATAACTATACACTGGAGTACAGGGGCGTTGTCAAAGTGAAAGGCAAAGGCGAAATGATGACCTACTTCCTAAACGGAGGACCCAATAACAGTTAACCCTCAGTGTCTGACCTTCAGAACATTATTAAGATGTCACAAGGAGGAGATGCTGTTGGCCAAGCTGTTGAGACGGTCATCCTTCTGGACCAATCGCAATAGGATTTGTTCAGAACCAGTCGTCACTCAGTCCAAGAGTGGCCTC
>TCONS_00074614
ATGTCCAGATCTAACAGCGTGAGCCCACCCGGCGCTGGCGCTCCTGGACTGAGGGGAGGGACGGAGCACAGATCCGCTTGGGGCGAGTCTGAGTCCGTGGCGAACGGATGTCCATACTCGGCCAGATCCTCCTGCAAAAAGCTCATACGGTCCAACAGTCGCTGGAGAGAGGACGATGACTTCGAGCGACAACCGGGCCGAGCCACGACCACCGTCAGCCGGGTTAGCTTCAGATCCAAGTCCGCCTGGCAGGAACAAGGCGAGGAGAGCCGCAACAACAACCGATCGTCCCCGAGGTACCGAGATGGAGAAGTGAGACCCAAATCCGTGGAGCTGGGTCTGGAGGACAGGAGAACCAAGTCCAAACCAGAGGAGGAGCTCATGCCTGAAGTGAACTTTTCCATGAGCGCGTGCTGCAACAGCGTGATGCAGATTTTCAGGTCCAAGAAGTTCCAGTCGGAGAAGTTGGAGAGACTCTACCAGCGCTACTTCTTCCGCCTGAACCAGAGCAGCCTGACGATGCTGATGGCCGTGCTGGTGCTGGTGTGCGCGGTGATGCTGGGCTTCCACTGCGCCGGAGGGATGTGCCAGCTCACCTTCGTGCTGGTTTTCACCGCGGCGATCGTGCTCATCCTCACGCTGATGGTGGTGTGCAACAGGAACAGCTTCCATCAGGATCACATGTGGATAGTTTGTTATTTGCTGATTTTGCTGGTGCTGGCCGTGCAGGTAGTCGGCGTGCTGTTCGTCAAGCCGCGGAGCGCGTCTGAAGGCATCTGGTGGACCGTGTTTTTCATCCACGTCATTTACACGCTTCTGCCGGTGCGGATGAGAGCGGCGGTGATCACTGGGATTATATTGTCTGCCATTCATGTGCTCATCTCGTGGAGGTTAAACGACATGGACGTCTTCTTGTGGAAGCAGCTGGTGTCCAATGTCCTGATCTTCTCCTGCTCTAATATAGTTGGTGTGTGCACACACTACCCAGCAGAAGGTTCTCAGAGACAGGCCTTCCAGGAGACCAGAGAATGTATTCAAGCCCGTCTGCACTCGCAGAGAGAAAACCAGCAACAGGAGCGTCTCCTCCTCTCTGTGCTTCCTCGTCATGTGGCCTTGGAAATGAAAGCCGACATTAATGCCAAACAGGAGGATATGATGTTCCACAAAATCTACATTCAGAAGCATGACAATGTGAGTATCCTCTTTGCTGACATTGAGGGCTTCACCAGTCTGGCTTCCCAGTGCACTGCCCAGGAGTTAGTGATGACCCTCAACGAGCTTTTCGCACGATTCGACAAACTGGCCGCCGAGAATCACTGTCTGCGGATCAAGATTCTGGGTGACTGCTACTACTGTGTGTCAGGGCTGCCGGAGGCCCGTGCTGACCATGCGCACTGCTGTGTGGAGATGGGAGTGGACATGATAGAAGCAATCTCCTTGGTGAGGGAAGTCACCGGTGTGAACGTCAACATGCGTGTTGGAATACACAGCGGGCGCGTTCACTGCGGGGTGCTGGGATTAAGGAAATGGCAGTTTGATGTCTGGTCCAACGATGTCACCTTGGCCAACCACATGGAAGCTGGGGGCAAAGCAGGGCGTATACATATCACCAAGGCCACTCTAAACTACCTGAATGGGGATTATGATGTGGAACCTGGATCTGGTGGAGAAAGAAACGTGTATCTCAAGAAGCACAACATTGAAACCTACCTCATTGTGGGCTGCAGTCAGAAGCGGAAAGAAGAAAAGGCCATGATTGCTAAGATGAACCGACAGCGCACCAACTCGGTCACTCATAACAGCACTCACTGGACCGACCGGCCCTTCTATAATCACCTGAATGCCAATTCTGTTTCCAAGGAGATGAAGAGGATGGGATTTGAGGATCCCAAAGACAAAAACACGCAAGAGAACCTGAATCCAGAGGATGAGGTGGATGAGTTTCTGGGCCGCGCCATTGATGCTCGGAGCATCGACCGGTTAAGATCTGAACACGTCAAGAAATTTTTGCTGACCTTCAGAGAACCTGATCTGGAGAAGAAGTACTCTAAACAGGTGGATTCCAGTTTCGGTGCATATGTGGCCTGCGCCTCCCTCGTCTTTTTATTCATCTGCTTCATTCAGATCATCATTGTGCCGCATTCTGGACTGATGGTTGGTTTCTATGTGCTCTGTCTGGTCGTTCTGATGGTGGTCATGTTCATCTCAGCCATTTACTCCTGTTTTGGGTTCACCTGCAGTACGGATGACCTGAAGACGTgtttagggcaggagtttaacatcAGCCCCAGCAATGTGAACGCTTGCCATGCCCATTTCTCTTCCCTCAACTACACACTCTGGTCTCAGAACAGGCTCTGCAACAGTTCGTCACCAACATGCAATTTCCCAGAGTACTTCTCATCATGTGTGCTGCTCAGTTTGCTGGCCTGCTCAGTTTTTCTACAGGTCAGCAGTATCGGTAAACTCTTCCTCATGCTCTTCATTGAGATCCTGTATGTGCTTATCATGGAGGTGCCCGAGGTCAGCCTTTTTGACAATGTGGACCTGCTGGTCATGGCCAATGCCCTAGCGCCTAACAATGGAACATGTATTGTGGACACCCGGGTTCCTCTAAAGATCGTGACTCCAGTGGTCATCACAGTCTTTGTGCTGGCGCTTTACCTTCATGCACAGCAGGTTGAGTCCACCGCCAGACTCGACTTTCTATGGAAGTTACAGgccacagaggaaaaggaggagatggaaGAACTTCAGGCTTACAATCGTCGGCTTCTTCACAACATCTTGCCCAAAGATGTGGCTGCACACTTTCTGGCCCGCGAGCGGAGGAATGACGAGCTGTACTACCAGTCGTGTGAATGTGTGGCTGTCATGTTTGCCTCCATCAGCAACTTTTCCGAGTTCTACGTGGAGTTGGAGGCCAATAATGAAGGTGTTGAATGCTTGAGACTTCTCAACGAGATCATCGCTGACTTTGACGAGATCATAAGTGAGGATCAGTTCCGTCAACTAGAAAAGATCAAAACCATTGGCAGCACCTACATGGCTGCATCTGGGCTTAATGACTCCACTTATGATAAAGCAGGAAGGTCACACATTCGCGCTCTAGCCGACTATGCCATGCGCCTCATGGACCAGATGAAGTACATCAATGAGCACTCTTTCAATAACTTCAAAATGAAGATCGGTCTCAACATGGGTCCTGTTGTGGCTGGAGTCATAGGAGCTCGTAAACCACAATATGACATATGGGGGAATACTGTGAATGTAGCCAGCCGTATGGACAGCACTGGGGTACCTGAGAGAATACAGgtCACAACGGACCTTTACCAGGTTCTCAGCTCCTATAACTATACACTGGAGTACAGGGGCGTTGTCAAAGTGAAAGGCAAAGGCGAAATGATGACCTACTTCCTAAACGGAGGACCCAATAACAGTTAA

Function


symbol description
adcy5 Predicted to enable adenylate cyclase activity. Acts upstream of or within regulation of protein phosphorylation and response to ethanol. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain; head; and heart. Orthologous to human ADCY5 (adenylate cyclase 5).

GO:

id name namespace
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway biological_process
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway biological_process
GO:0045471 response to ethanol biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0006171 cAMP biosynthetic process biological_process
GO:0009190 cyclic nucleotide biosynthetic process biological_process
GO:0001932 regulation of protein phosphorylation biological_process
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004016 adenylate cyclase activity molecular_function
GO:0016829 lyase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016849 phosphorus-oxygen lyase activity molecular_function

KEGG:

id description
ko00230 Purine metabolism
ko04015 Rap1 signaling pathway
ko04371 Apelin signaling pathway
ko04072 Phospholipase D signaling pathway
ko04024 cAMP signaling pathway
ko04022 cGMP-PKG signaling pathway
ko04114 Oocyte meiosis
ko04540 Gap junction
ko04611 Platelet activation
ko04062 Chemokine signaling pathway
ko04911 Insulin secretion
ko04923 Regulation of lipolysis in adipocytes
ko04912 GnRH signaling pathway
ko04913 Ovarian steroidogenesis
ko04915 Estrogen signaling pathway
ko04914 Progesterone-mediated oocyte maturation
ko04921 Oxytocin signaling pathway
ko04926 Relaxin signaling pathway
ko04935 Growth hormone synthesis, secretion and action
ko04918 Thyroid hormone synthesis
ko04928 Parathyroid hormone synthesis, secretion and action
ko04916 Melanogenesis
ko04924 Renin secretion
ko04925 Aldosterone synthesis and secretion
ko04927 Cortisol synthesis and secretion
ko04261 Adrenergic signaling in cardiomyocytes
ko04270 Vascular smooth muscle contraction
ko04970 Salivary secretion
ko04971 Gastric acid secretion
ko04972 Pancreatic secretion
ko04976 Bile secretion
ko04724 Glutamatergic synapse
ko04727 GABAergic synapse
ko04725 Cholinergic synapse
ko04728 Dopaminergic synapse
ko04726 Serotonergic synapse
ko04723 Retrograde endocannabinoid signaling
ko04750 Inflammatory mediator regulation of TRP channels
ko04211 Longevity regulating pathway
ko04213 Longevity regulating pathway - multiple species
ko04713 Circadian entrainment
ko04714 Thermogenesis
ko05200 Pathways in cancer
ko05207 Chemical carcinogenesis - receptor activation
ko05166 Human T-cell leukemia virus 1 infection
ko05163 Human cytomegalovirus infection
ko05012 Parkinson disease
ko05030 Cocaine addiction
ko05031 Amphetamine addiction
ko05032 Morphine addiction
ko05034 Alcoholism
ko05414 Dilated cardiomyopathy
ko04934 Cushing syndrome
ko01522 Endocrine resistance

ZFIN:

id description
ZDB-GENE-081104-470 Predicted to enable adenylate cyclase activity. Acts upstream of or within regulation of protein phosphorylation and response to ethanol. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain; head; and heart. Orthologous to human ADCY5 (adenylate cyclase 5).

Ensembl:

ensembl_id ENSDARG00000091342

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00074613 False 3814 mRNA 0.51 21 37872577 38021997
TCONS_00074614 True 3444 mRNA 0.52 20 37872722 38021889

Neighbor


gene id symbol gene type direction distance location
XLOC_038034 BX511075.1 coding downstream 52365 37817266 ~ 37820212 (-)
XLOC_038033 sema5ba coding downstream 122604 37481434 ~ 37749973 (-)
XLOC_038032 hspbap1 coding downstream 505100 37341240 ~ 37367477 (-)
XLOC_038031 NA coding downstream 735321 37118184 ~ 37137256 (-)
XLOC_038030 NA coding downstream 852106 37015729 ~ 37020471 (-)
XLOC_038036 hacd2 coding upstream 7478 38029475 ~ 38042939 (-)
XLOC_038037 NA coding upstream 48087 38070084 ~ 38071916 (-)
XLOC_038038 si:dkey-219c10.4 coding upstream 118914 38140911 ~ 38156894 (-)
XLOC_038039 BX548038.3 coding upstream 182410 38204407 ~ 38204528 (-)
XLOC_038040 NA coding upstream 329584 38351581 ~ 38352885 (-)
XLOC_038029 NA non-coding downstream 912916 36956993 ~ 36959661 (-)
XLOC_038028 NA non-coding downstream 931827 36926826 ~ 36940750 (-)
XLOC_038043 BX001051.1 non-coding upstream 447449 38469446 ~ 38469566 (-)
XLOC_038044 NA non-coding upstream 536642 38558639 ~ 38560263 (-)

Expression



Co-expression Network