XLOC_038058 (abca12)


Basic Information

Item Value
gene id XLOC_038058
gene name abca12
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 40685613 ~ 40765868 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00074643
GTCCCTTCTGTATGAGCCTGTTCTTAGACATGGTGAACACTACAGGCGGTGCGGTGGCTTGGGCTTTCCTTAAGCCAATGCTGTTAGGACAGATCCTGTACTCTCCGGACACACCAATGACCAGAGAGATCATGAGAAAGTCAAATTCCTCACTTCACCAGTTTGGTGACCTAAAGCTGTATGCGTCCGAGTGGATCGAGTCATCGTCCTATGTGCTGCAGTCTGCCAACATTTTGACACAAACCTTGCCGATACTTAAGAATTCCCTGAACAGTCCTTTTGTCCAAAACTTCATTCGGACTCAGACTGGAATTGACGTTTCAGGAATGAGTGCAACTCTCAACCAATTCTCGAACATGACAGTCCTGTTAGAGAAAAACAAGTTTATCATGGACCAGATCACCACCCTCTCTGTGCTCATGATGAACCTCTCCTCCTGTGTCAACTTCGACCGATACCGAGGCTTCAACTCTACTGATGAACTCGACAAGCAAGccgaaaaactggctcaaaaccGTGAGCTGTATGCCAGCATTATTTTCAAACTTCCCAAGGAGAACTCCAGCAGCCTGCCACCAAACATCGACTACACCATACGCATGAACATCGAGAATGTCATGCGCACAGACCGTGCACGCAATCCCTTCTGGGTGAAAGATGCCTACATATCGGCAACCAGAACCCAGCGGTACAGCCGAGGCTTTGTGTACCTGCAGGAAAGCATCGAGAGGGCCATCATCGAAATGCAGACGGGTAATGCCATGGATGGGCCCGCGGTCCAGATGCAGGCATTCCCTTATCCCTGCTACTATAAGGACGAATATCTCAACAGCATCGCGTTTGCCTTCCCAATGGCGCTCATGATTTCCTGGGTGCTGTTTATTGCACACTTTGTCAAGAAACTAGTGCACGAGAGAGAGCTGCGTCTTCACGAGTACATGAAAATGATGGGGGTCAATCCCATCAGCCACTTCTTTGCCTGGTTAATTGAGAGCGGTGCGTTCCTGTTGGTGACCGTCATCATCCTCACCATCATTCTGAAGGCTGGCGGGATCCTTCCTCGCAGCGATGGATTTGTGCTCTTCCTCTACCTCTGCGACTACGGCTTCAGCGTCCTCGCGGTCAGCTTCCTGGTCAGCTCCTTCTTCGATAAGACCAACATCGCCGGGCTGAGTGGCAGCCTTATCTATGTCATCTCTTTCTTCCCCTTCATTGTGCTGATCCACTTGGAGGACAACCTCTCCTTCTCTGTGAAGAGCGCTCTGAGTCTCTTTTCTCCGACATGCTTCAGTTATGCCAGCCAGTACATCGCCCGCTATGAAAAGCAGGAAGAAGGCATCCAGTGGAGCAACATGTACATCTCTCCTCTGGCTGGCGACACCTCCTCCTTCGGCTGGCTCTGCTGGCTGCTCTTAATTGACTCGCTTGTATATTTCATCATTGGGATTTACATCCGCATGGTCTTTCCAGGAAAGTATGGCATCGCTGTACCGTGGTATTTCCCAGTAACTAAATCCTTCTGGACGGATATGTTCAGCTGTTGTAGCAAGACACCTAAGAAAATAGGGAGAGGGCTGCTGTTTACCAACATGATGCAGGACCAAAGCAGCATGAACAAGAGCAAAGgAAAAGGTAGCTTGGTGGCTAAAGGAGAAGAAGACTTCTCAGGGTTGCCCGTTGGAGTCTCACTGTATGGCCTGACGAAGACCTACGGCAAGAGGAATGCTGTAGACAACCTAAACCTGTCTTTCTATGAGGGACACGTCACCTCTCTGCTGGGTCACAATGGAGCTGGAAAAACCACCACTATgTCACTTTTGACTGGATTGTTTGCACCCACTGTCGGCACCATTGAGGTCTACGGGATGGATATGCAGATGTTCATAGATGATGTGCGCAAGGAGATGGGCGTCTGTATGCAGTATGACGTCCTGTTCGACCATCTGACCACTAAAGAGCATCTGTTACTGTACGCTCAGATCAAAGCTCCTCATTGGACCAAGCAAGAAGTGAAGGAACAAGTGCACAAAATCCTAATGGAAACAGACATGCATGCCCACCGGCACAAGCGTGTTGGCACTCTGTCAGGAGGCATGAAGAGAAAGTTATCCATCTCCATTGCCTTCATCGGAGGCTCGCGGCTGGTGGTGTTGGATGAGCCGACCACCGGCGTAGATCCATGTTCCCGACGCAGTATCTGGGACATTATCATACAGCACAAACAAGAGCGTACCATCATTCTTTCCACACATCACCTGGACGAGGCTGAAGTTCTCAGTGACCGCATCGCTTTTCTGGAGCGCGGAGGCCTCAAGTGCTGCGGTTCACCCTTCTATCTCAAAGACAAACTCGCTAAAGGATACAACCTCACCCTCACTAAGAAGGTCGAGACTGCCGACTCAAAGGAGAAGTTTGACTATGAGAAACTCAGGGATTTCATTCATTCGCACCTACCTGATGCCCGACAGAAGGATAGAGAGATGGGTGATCTAGTCTATGCCTTGCCACCGTACACCCCTCAAAACGCCTCTGAGTACCACTCTCTGCTTAACAGCCTGGATCAGAATCTGGACAAGCTTCACCTAGGCTGCTATGGCATCTCTGACACCACCCTGGAAGAGGTGTTCCTGCAGTTGACTCGAGATGACCTCGAGCCCAAAGAAAGTGAAACCTGGTCTGTATCAGAGTCGGTTATAGAGAATGACATGTTCGCCTCAAGAGACAGTCTTTCTGAAGACTGCAACAGCATGTACCTTGGAGAGAAAGCCAGCCTCACAGGGAACTCGACGGTGCGTGGATTTGCTTTGGGTGTTCAGCGTGTGATAGCCATGTTGCTGAAGCGCGTGCATCACTCTAGGAGGGACTGGAAGGGGCTTTTCTCTCAGGTGCTGTTGCCTGTACTCTTTGTAATTGCTGCCATGGGCTTGGGCTCCATCAAGAGTGATCTTCAGCATTTTCCTGAGATTGTGCTCTCTCCTGCGCTCTACCACGTTGATGAACAGTACGCCTTCTTCAGCAATCAAAATCCCAACACCAGCCGTCTTGTCGACACCATGATGTCCTATCCAGGCATAGACCACGTGTGCATGACAGACCCCACAGATCCTGTTTGTAAAGGAAGACCTTCGACAGGAAGTCAGACGTGGGTCTCCGGAGGCAACAGCTCTGCTACATTTACCACCTGCAAGTGTAGCAACCAAGTGCAGTCATGTCCGGCACAGGGTTACGATCCACCTCGCAAAAGATGTCCATCATCCCAGATCGTCTATAACCTTACGGGCGTCAACATTGAAAACTACCTGCTGGCTACTGCCAATAACTTCATCAGAGACAGATATGGAGGCTGGGAGTTTGGAAAGCCTCTTCCCATTGATCTTAAGATGGACATGTTAGATGTGCCAGCAAACAGAACCCTTAGTAAGGTTTGGTATAATTCAGAAGGTCACCACTCTATGCCAGCCTACCTCAACAGCCTTAACAACTTTTTCCTGAGATCCAGTTTGCCACCTGAGAAACGATATCAATACGctatTTCCATATCCAGCCATCCTTACCCTGGCCAAGTGCAAGACGAGGATCTCATGGTGGGCGGTCTGGTCAGCATCCTGGTTGCGCTCTGTGTCCTCACTGGCTACTCCATCATGACTGCTAGCTTTGTCATCTATGAGGTTCAGGAACATCACACAGGCTCCAAGAGACTACAGCAAATCTCTGGCATCAGCGAACCTTTTTACTGGATCATCAACTTCTTCTATGATATGGCTCTATACATGATTCCAGTGGTGCTGTCGGTGGTGATGGTCGCAGCATTTCAGCTCCCAGCCTTCACAGAGAGACAGAACCTTGCCGCGGTCACACTCCTACTGGTGCTATTTGGATTTTCCACCTTCCCTTGGATGTACCTTCTATCCGCGATGTTCAAAGATACAGAGATGGCTTTCATTGGTTATGTTTGCATCAATCTCTTCATCAGTGTCAACACCATCATTTCCACATCCATCATATACTTCCTCGGTCAGCTCAACCAGAATGACCAGAGCATCCAGAATATCTACCAAACCATGAGCAACATATTTCTAGTCTTCCCTCAGTTCAGCTTTGGCAATGGGTTGATGGAGCTGGCACGGGTTGACATGCAGGTGCAGATCTTGAGCGGTTTTGGAGTGGATGCCTACAAGAACCCCTTCAGCATGGATGTTCTGGGCTGGATGTTCATTTCCATGTTCCTGCAGGGCTTCATCTGCTTCACGCTCCGCCTGCTGCTTAACAAGACACTCCTTCGCAAAGTCAGGCGGTTATTCTGCTGGAAGAGGAATGCTGTTCAGAGTTATAGTCCTAATGAAGATGAAGATGTGCTGGATGAACGTCTGCGTGTGGGCCGTGGAGATGCAAGCTCTGATATTCTGCAGGTTAATCACCTGACTAAGGTGTACCAAAACTTCAGCAAGAGGGTACAGGCGGTGAAGAGTCTGTCTGTGGGCATCCCAGCTGGCgagTGCTTTGGATTGCTTGGAGTCAATGGTGCAGGAAAGACCACTACCTTTAAGATGCTGACGGGAGACATCAGCCCTTCTGGCGGCTCGGCCAAGATCCGTGACATTGACGGGAGGATGGTTGACATCATAGACTGCAGGAGAGAGGGCATAAACATTGGTTACTGCCCTCAGGTGGACGCACTGGATGACCTTCTGACTGGGGAGGAACATCTCTATTTTTACGCCCGCATCAGGGGCATCTCCAAGAGGGACATTAGCCAGGTTGTGAACTATCTGTTGAAAAAATTGCAGCTGAATTACCACAGAAACAACACAAGCGAGAGCTACAGTTGCGGAACCCGCCGGAAACTCTCGACAGCCTTAGCCCTCATCGGAAACCCTCAGATCCTTCTCCTGGATGAGCCCAGCTCTGGAATGGACCCACGATCCAAACGGCATCTCTGGAAGATCATCTCTGAACAAGTGATGGGCAAATGCGCGGTGGTGCTGACATCACACAGTATGGAGGAGTGTGAGGCTCTTTGCACTCGTCTGGCCATAATGGTGAAAGGACAGTTCAGATGCCTGGGTTCCCTACAGCACATCAAGAACAGGTTCGGCAGCGGGTTCACGGTGAAGATGTATTTAACCGGAGCCTCCTATGATGTAGATATGATCAGTAACTTCATGCAGCAGAACTTCCCCGGCACGTGCCTGAAGGATAATCATTCCAATATGGTGGAGTATCATGTGCCTGTTGCTCCTGGTGGTGTGGCTTCAATCTTCAGCCTGTTAGAGTCCAACAAGACAGTTCTGCAAATCAAACACTTTTCAGTCAGCCAGACCACGCTGGATGAGGTGTTCATTAACTTTGCGACGGCAAAAGTGGACACAGATGGACTTGAGGCCACTGAAGGATCCGACATCGACAGCCTAGACTCCTTCAACACTTAAGACTGATGCCCGACACTTGCACATTATGACAATTAGCGAAGAAAAGAAAATCAGTTATagcttatatattaatttaatgttGTGATTTTAATGAAAGATATATGTATTGTATTGAACAATGAAGTCGCCAAATACCTTGTGGATTTTAAttgaagattattattattattattatgaggaatTATGTGTAAATGACTCTCTTTCTGCTCTTATACTGATCAGCATTAAAGGGACCATTTAATGGAAGTGGTGGGGTTAAGTATGCAGAAAGTCTACTCTAGTTTACATAGTTTACATGCAAATCCATTAGCCGATCATTTGTCCTCAAACTAATCCACTGCTGCTTCTTCTCCAACAAAATGAAGgcatttatttagtaaattatttgACGTTTTATTAGCTCTACTACTAGATATATAGGTACTGTAATGGAAATCTGAATAATTGACACGAACAACCAACAATGTGTTACTGGTTGCAGAATGAAATATGTATGCGAGAAGTCCGTACTCTTAAACTGCCGGCCTGCATCCATGTCTGGGGTTGATATAAATCACAAAGACCTTTTTGGCTCGGAGATATAAATGATTCTTCAATGTCTGCACATCTTCGCTCTCATTAATATTTCCTCTGAAGGCACATCTCTTGTGCAAGAATGTACTGAATATTTCATCGGCCCTTTCTCTGTCTGCTTCAAGGCACGGTTCCTCTTTTAAAAAATGCACCAagcttatttttacattaaagCTATTTTTCACATGCA
>TCONS_00075442
TGTTTGTAAAGGAAGACCTTCGACAGGAAGTCAGACGTGGGTCTCCGGAGGCAACAGCTCTGCTACATTTACCACCTGCAAGTGTAGCAACCAAGTGCAGTCATGTCCGGCACAGGGTTACGATCCACCTCGCAAAAGATGTCCATCATCCCAGATCGTCTATAACCTTACGGGCGTCAACATTGAAAACTACCTGCTGGCTACTGCCAATAACTTCATCAGAGACAG

Function

symbol description
abca12 Predicted to enable ATPase-coupled transmembrane transporter activity; apolipoprotein A-I receptor binding activity; and lipid transporter activity. Acts upstream of or within epidermis morphogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in EVL; ectoderm; integument; peripheral olfactory organ; and pharynx. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1; autosomal recessive congenital ichthyosis 4A; and autosomal recessive congenital ichthyosis 4B. Orthologous to human ABCA12 (ATP binding cassette subfamily A member 12).

GO:

id name namespace
GO:0048730 epidermis morphogenesis biological_process
GO:0055085 transmembrane transport biological_process
GO:0006869 lipid transport biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043231 intracellular membrane-bounded organelle cellular_component
GO:0034191 apolipoprotein A-I receptor binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0022857 transmembrane transporter activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016887 ATPase activity molecular_function
GO:0042626 ATPase-coupled transmembrane transporter activity molecular_function
GO:0005319 lipid transporter activity molecular_function

KEGG:

id description
ko02010 ABC transporters
ko02000 Transporters

ZFIN:

id description
ZDB-GENE-030131-9790 Predicted to enable ATPase-coupled transmembrane transporter activity; apolipoprotein A-I receptor binding activity; and lipid transporter activity. Acts upstream of or within epidermis morphogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in EVL; ectoderm; integument; peripheral olfactory organ; and pharynx. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1; autosomal recessive congenital ichthyosis 4A; and autosomal recessive congenital ichthyosis 4B. Orthologous to human ABCA12 (ATP binding cassette subfamily A member 12).

Ensembl:

ensembl_id ENSDARG00000074749

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00074643 False 6192 mRNA 0.48 36 40685613 40765868
TCONS_00075442 True 228 lncRNA 0.50 2 40724279 40726698

Neighbor

gene id symbol gene type direction distance location
XLOC_038056 bard1 coding downstream 1845 40617215 ~ 40683768 (-)
XLOC_038057 NA coding downstream 66598 40618165 ~ 40619015 (-)
XLOC_038055 CU367848.1 coding downstream 175970 40509529 ~ 40509643 (-)
XLOC_038054 NA coding downstream 200759 40388580 ~ 40484854 (-)
XLOC_038053 BX936447.1 coding downstream 300366 40385130 ~ 40385247 (-)
XLOC_038059 CR932999.1 coding upstream 1187 40767055 ~ 40777341 (-)
XLOC_038060 si:dkey-95p16.1 coding upstream 63601 40829469 ~ 40846447 (-)
XLOC_038061 pofut2 coding upstream 85220 40851088 ~ 40873934 (-)
XLOC_038062 BX323586.3 coding upstream 161409 40927277 ~ 40935934 (-)
XLOC_038063 BX323586.2 coding upstream 177251 40943119 ~ 41025062 (-)
XLOC_038052 NA non-coding downstream 335444 40080890 ~ 40350169 (-)
XLOC_038066 CT737230.1 non-coding upstream 306952 41072820 ~ 41072935 (-)
XLOC_038068 NA non-coding upstream 329578 41095446 ~ 41101432 (-)
XLOC_038070 NA non-coding upstream 404734 41170602 ~ 41172834 (-)

Expression


Co-expression Network