XLOC_038719 (setdb2)


Basic Information

Item Value
gene id XLOC_038719
gene name setdb2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NW_003334027.1
NCBI id KN150699.1
chromosome length 26100
location 8780 ~ 12431 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00076190
ATGGAGACTGAAGCCGACACAGCAAAGACCTTCTGGTCAGAGGTGGATGTTGATGGAGTGTTTGATGAGCTGATGGAGGTTTTGAGACGCTTAcgacacacactcagacacaacaCTGCCACTGACagagagtatGTTCAGGCCATGAGGATCGTCCAGGAGTCTAAGCTGATAAGGACTGAAACTGAAGACTTGCTGTTGGATGAAGatatCCTCACAGTGACGGTGTCTGAGCCTCAGTGTTCTCCTGAGAGTCTGCAGAATGGCATCGAGCCGGAGGATCCTCAGCACAGCACGGCACGGCTCTACAGTGATGTGGGCGTGGTCTGCAGTCACATGTCCTCCAGCAGGCCTGATCCCGCAGCTCCTCTCGTCTTCCAGCCGCACGTCTGCAGCTCCGCGTGTGTTCCGCATCtgcccgcacacacacaccacctgcTGGGCCACAACCCGCTGCGCGCGCCGCTGCTGTGCCACTTCCAGCGTGTGTGTGACGACGCGGGCGTGGTTTACAAAGCGCCGTGTGGGCGGAGCCTGAGCTGCATGCAGGAGGTGCTGCACTTCCTGCTGCAGACGCAgattgtgtgtgtgctgcagacGGACCACTTCAGCTTCAGCACGCAGGTGTGTGTGGAGCGGCAGGTGTGTGCGGCGCCGCTGCTGGAGCGGGACCTGAGCCGCGGGCTGGAGCCGGTGCCGGTGGCTCTGGTGAACACTGTGGACGGCGCGCGGCCGCGGGAGTTCCGGTACCGGAGAGAGCGCTGGCCGCACGGCTGCTTCCTCAGCGCAGAGCCGCTCTACAGTGTGTGCTGCGACTGCAACGACGGCTGCACTGATGCGCACAGCTGCGCGTGTGTGAGGAGGACAGCAGGAGCAGCGTACACACACCAgcgcctcacacacacactgcgcacaGGGTCAGtcatctgtgtgcgtgtgtgtgcgctaatcatgagtgtgtgtgtgttggttcatatcatgagtgtgtgtgtgtgtgtgtgtgtgtcacacacacacacacacagacttactTATAAACACACAGATATATACGCACCTGCAaacttactcacacacacacacgcatacacagacTCTGAAtgcagcagtgtgtgttGTTCCTCTGTTTCAGGATCAGCAGCAGTTCAGCATCAGCAGCGAGACGGGTACAAACAGACNTNANacacacacacacacacacacacacaaacctccaGACCAACTGAACacctgtgtgtgtgtatgtgtccatgtgaatgtgtgtttgtatatatgtgtgtgcatatacagtacattgtgtgtgtgtgtgtagaggatGATCAGTGTGAGCAGGCGTTGAGAAAGAAGCCCAGATTAATGGAGTCAAACGGTCTGCAGGACAGCAGGACacacactgtcacacacacacatgacggAGTGTATTATCTGGACGCGTCGAGGGAAGGAAACGTGGCTCGATTCTTCACCCACAGCGATGATCCAAACCTCTTCATCCAGAACGTGTTCACAGACACACACGACCCACAGTTCCCTCTGATCGCCTTCTTCACCTGCAGaccaGTGAAAGCTGGAACTGAACTGACCTGGAGCTGCACAAACACTGAACAGCAGAAGACAGAAGAGAAACACTGCAGTGTGtag

Function

symbol description
setdb2 Enables histone methyltransferase activity (H3-K9 specific). Involved in heart looping; left/right axis specification; and negative regulation of transcription, DNA-templated. Acts upstream of or within convergent extension involved in gastrulation; determination of left/right symmetry; and histone H3-K9 methylation. Predicted to be located in chromosome. Predicted to be active in nucleus. Orthologous to human SETDB2 (SET domain bifurcated histone lysine methyltransferase 2).

GO:

id name namespace
GO:0006325 chromatin organization biological_process
GO:0034968 histone lysine methylation biological_process
GO:0010629 negative regulation of gene expression biological_process
GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly biological_process
GO:0070828 heterochromatin organization biological_process
GO:0007275 multicellular organism development biological_process
GO:0007049 cell cycle biological_process
GO:0007059 chromosome segregation biological_process
GO:0051567 histone H3-K9 methylation biological_process
GO:0045892 negative regulation of transcription, DNA-templated biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0051301 cell division biological_process
GO:0060027 convergent extension involved in gastrulation biological_process
GO:0032259 methylation biological_process
GO:0001947 heart looping biological_process
GO:0070986 left/right axis specification biological_process
GO:0000278 mitotic cell cycle biological_process
GO:0005634 nucleus cellular_component
GO:0005694 chromosome cellular_component
GO:0016740 transferase activity molecular_function
GO:0008168 methyltransferase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0046974 histone methyltransferase activity (H3-K9 specific) molecular_function
GO:0018024 histone-lysine N-methyltransferase activity molecular_function

KEGG:

id description
ko00310 Lysine degradation
ko03036 Chromosome and associated proteins

ZFIN:

id description
ZDB-GENE-030131-7093 Enables histone methyltransferase activity (H3-K9 specific). Involved in heart looping; left/right axis specification; and negative regulation of transcription, DNA-templated. Acts upstream of or within convergent extension involved in gastrulation; determination of left/right symmetry; and histone H3-K9 methylation. Predicted to be located in chromosome. Predicted to be active in nucleus. Orthologous to human SETDB2 (SET domain bifurcated histone lysine methyltransferase 2).

Ensembl:

ensembl_id ENSDARG00000101462

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00076190 True 1641 mRNA 0.55 13 8780 12431

Neighbor

gene id symbol gene type direction distance location
XLOC_038720 creg1 coding downstream 2956 15387 ~ 19509 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000299_06312445_06318421 NA coding CI01000299 null 6312040 ~ 6318421 (+)