psen2 (psen2,LOC100710620)


Basic Information

Item Value
gene id psen2
gene name psen2,LOC100710620
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053112.1
NCBI id CM020909.1
chromosome length 48724115
location 3647024 ~ 3655642 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039808845.1
TAAGGTAGTAGTACTGTAAGGTAGTACTGTAAGGTAGTAGTACTGTAAGGGAGTATTTGTCCCGGCAGGATCTACACGCCCTTCACGGAGAACACGGCCTCGGTGGGCCGCCGGCTGCTGAACTCGGTCCTCAACACCATCATCATGATCAGCGTCGTCGTGGTGATGACCGTCTTCCTGGTCGTCCTCTACAAGTACCGCTGCtacaagtTCATCCACGGCTGGCTCATCCTGTCCTCCCTCATGCTGCTCTTCTGGTTCAGCTTCATGTACCTCGGCGAGGTGTTTAAGACGTACAACGTGGCGGTGGACTACCCGACGGTTGCCGTGGTGATCTGGAACTTCGGGGGGGTGGGGATGATCTGCATCCACTGGAAGGGCCCGCTGGCGCTGCAGCAGGCCTACCTCATCCTCATCAGCGCCCTCATGGCCCTCGTCTTCATCAAGTACCTCCCCGAGTGGTCGGCCTGGGTCATCCTGGGCGCCATCTCCGTCTACGACCTGGTGGCCGTCCTGTCCCCTAAAGGTCCTCTCCGCATGTTGGTGGAGACGGCACAGGAACGCAACGAGCCCATCTTCCCCGCCCTCATCTACTCCTcGGCCATGATGTGGACAGTGGGGATGGCGAGCCCAGCGGACGCTCAGCGCTCCGGACACGAAACAGACGAGGAGGCGGAGCAGAGCGGTGGGGGGGCGGAGCCTGAGAGCAGCGGGGGGGCGGAGCCTGAGAGCCGACAGCCCCGGCCGTTTACAGACAGCGAGCTGGAGGAAGACCgGGGGGTGAAGCTCGGCCTCGGGGATTTCATCTTCTACAGCGTTCTGGTTGGAAAAGCTGCCGCGACCGGCGGAGACTGGAACACCACGCTCGCCTGCTTTGTCGCCATTCTTATCGGTCTGTGCCTGacgctgctgctgctcgctATCTTTAAGAAGGCTCTGCCGGCGCTACCCATCTCCATCACCTTCGGCCTGGTGTTCTACTTCTCCACTGACTTCCTGGTTCAGCCCTTCATGGACAACCTGGCTGCCAACCAGTTCTACATCTGAGAGCAAGGCCCgccccctcccatctgagagcaAGCCCCACACCCTCCCATCTAAGAGCAAGCTCTActccctcccatctgagagcaagctctactccctcccatctgagagcaAGCCCCACACCTTCGCCATCTGAAAGCAAGCTCTActccctcccatctgagagcaAGCTCTACTCCCTCCCATCTGAAAGCAAGCTCTActccctcccatctgagagcaagctctactccctcccatctgagagcaAGCCCCAgaccctcccatctgagagcaAGCCCCAgaccctcccatctgagagcaAAGACCaccccctcccatctgagagcaAGCCCCAGACCCCTCCTATCTGAGAGCAAGTCCCAAACCCTCGCCATCTGAGGGCCAGCATTGATGTAACACACAAAGACTACTTCCTGTCTCCTACCTTCTCTAAAAGTCTGTTTGAGGAACTCGATGCGTTGTCTGATACCTGCTGACGACTAGTTTAAACATCCTGTAACTCGTTTAGAGTCTCTGAATTCAAACGCTCGCCGTGACGTTTTGTTACTCCAAGCAGCGCGGCTGCGTGTGATTGGCTGACGCTGCCGTCAGTCCGAGCAAAACAGACCTGTAAAGATTCCCTCTGGAGATTTAAGCTTTTTATTGTGTCCTGTCCTGGCTGCCGGTGTCTGTTCTCCACCTGGAGCATGTTGTTTAAAGTCCTGctgacattatttcttcataaTGTAGTCAGACACTTCTCTGTAACGGACGCAGGTTCTTCCCTCTTTAACACTACACCAGCTGCTTTGATTTGTTGCTCTGGAAgctgatttgtatatttaacaTTGTATTAATAATTTGGAATAAACGTGTCTGTGAGGAT

Function

symbol description
psen2 Predicted to enable endopeptidase activity. Acts upstream of or within several processes, including amyloid-beta formation; melanocyte differentiation; and nervous system development. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including Z disc; ciliary rootlet; and dendritic shaft. Predicted to be integral component of plasma membrane. Is expressed in female organism; heart; male organism; and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Alzheimer's disease 4; breast cancer; and dilated cardiomyopathy 1V. Orthologous to human PSEN2 (presenilin 2).

NR:

description
presenilin-2

GO:

id name namespace
GO:0008152 metabolic process biological_process
GO:0016021 integral component of membrane cellular_component
GO:0004190 aspartic-type endopeptidase activity molecular_function

KEGG:

id description
K04522 PSEN2, PS2; presenilin 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039808845.1 True 1915 mRNA 0.56 8 3647024 3655642

Neighbor

gene id symbol gene type direction distance location
LOC120562172 NA coding upstream 79014 3564722 ~ 3568010 (+)
LOC120555395 NA coding upstream 157014 3488343 ~ 3490010 (+)
rrbp1b NA coding upstream 198531 3413425 ~ 3448493 (+)
LOC120550686 LOC106676715 coding upstream 273883 3364816 ~ 3373141 (+)
LOC120557788 LOC100703858,LOC102778772,LOC103375691,LOC101465362,LOC107082671 coding upstream 487732 3157203 ~ 3159292 (+)
pgap4 NA coding downstream 588616 4244258 ~ 4247932 (+)
LOC120568266 NA coding downstream 597477 4253119 ~ 4269471 (+)
tpcn3 LOC103368820,LOC102314232 coding downstream 656965 4312607 ~ 4332900 (+)
rcor3 rcor3 coding downstream 843371 4499013 ~ 4517076 (+)
traf5 NA coding downstream 865457 4521099 ~ 4538660 (+)
G1207 NA non-coding upstream 67269 3561467 ~ 3579755 (+)
G1203 NA non-coding upstream 68157 3560301 ~ 3578867 (+)
G1205 NA non-coding upstream 92984 3553749 ~ 3554040 (+)
G1189 NA non-coding upstream 152261 3491944 ~ 3494763 (+)
G1156 NA non-coding upstream 204846 3435944 ~ 3442178 (+)
G1219 NA non-coding downstream 6210 3661852 ~ 3681929 (+)
G1222 NA non-coding downstream 9811 3665453 ~ 3669048 (+)
G1233 NA non-coding downstream 89690 3745332 ~ 3745706 (+)
LOC120569364 NA non-coding downstream 123066 3778708 ~ 3780003 (+)
G1324 NA non-coding downstream 227659 3883301 ~ 4118166 (+)
G1191 NA other upstream 147920 3496606 ~ 3499104 (+)
LOC120555387 LOC106675676,LOC106675675 other upstream 166894 3468124 ~ 3480130 (+)
dzank1 NA other upstream 387266 3175601 ~ 3259758 (+)
LOC120557752 LOC104935435,LOC108250455,LOC106524354,LOC101471560,LOC103371946,LOC102291612 other upstream 489886 3128089 ~ 3157138 (+)
LOC120567079 NA other upstream 575551 3068398 ~ 3071473 (+)
LOC120562910 NA other downstream 137104 3792746 ~ 3814570 (+)
pex6 pex6,LOC104944420,LOC104961583 other downstream 752796 4408438 ~ 4436086 (+)
G1487 LOC103369331 other downstream 799565 4455207 ~ 4460404 (+)
G1600 NA other downstream 1322141 4977783 ~ 5038714 (+)
G1756 NA other downstream 1562426 5218068 ~ 5222744 (+)

Expression


Co-expression Network