pink1 (pink1)


Basic Information

Item Value
gene id pink1
gene name pink1
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053116.1
NCBI id CM020913.1
chromosome length 44101041
location 10118685 ~ 10131254 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039800014.1
TATCGCGCATGCTCAGTAACAGTTGTTTTGTTTACCAAACTGTCTTTGCCTGAGATAGCAGAGGACTGCCTGACACAAGCGGACTCAATAAACCGCTTAAATTACCTTTCCGGGTAAATTATGTCTGTGAAACACGCTATTAGCCGGGGGCTCGAGTTAGGCCGCTCGGTCTTTCAGCTGGGGCTCCTGAAATCGGGTGGCCGAGTCGCAGCAAAGCTCCGAGCTGACCGTTTCCGTGTAGGCCCGTCGGTCCGCACCGTTCAGCCTCAGGCTTTCCTGCCGTCTCGGTACCGCTATTACCGCACCTCTTTGAAGGGCCTGGCAGTCCAGCTTCAGTCCGCCGGCTTCAGGAGAGGGTTTAGCGGCGGGTCCCCGCGAAACAGGGCCGTGTTTTTGGCTTTTGGCCTCGGTGTGGGGCTTATCGAACAACAGCTTGAAGATGACAGAAGTAGTGCGGCTACATGTGAGGAGATCCAGGCGGTGTTTAGAAAGAAAAGATTCCAGAGCCCACTCAAGCCATTCACCTCTGGATATAAACTGGAGGATTACATTATTGGGAATCAGATTGGGAAAGGCTCCAACGCTGCCGTGTATGAAGCTGCAGCTCGGTTTGCCCCTCCAAAGGACAGTACCAACAAGTGCTCGATGGTGCAGCtgagggaagaggaagaggaaggggagacGGCTCGATCTCTGACATGCTGCTCGCTAAGAACCTTCCCTATGGCTGTCAAGATGATGTGGAACTTTGGGGCCGGGTCGTCAAGTGAGGCGATATTAAAATCCATGTCACAAGAGCTGGTGCCTGCAGGCCCCCTGGCCTTAAAgcaggaaaaagaagaaattgcTCTGGATGGACAGTTTGGAGTCCTGCCCAAACAAGTATCAGCACACCCTAATGTGATCAGAGTGTACCGGGCTTTCACAGCGGACGTCCCATTGCTAGCAGGTGCCCAAGAAGAGTATCCAGATGTACTGCCAGCCAGGCTTAACCCTGCTGGTCTGGGCAACAATCGCACTCTTTTCCTCGTCATGAAGAACTACCCTGGCACGCTGCGACAGTACTTGGAAATGTCCACACCAGGCCGCAGGCAGGGCTCTctgatggtgctgcagctccTGGAGGGGGTTGACCACCTGTGCAGACAGGGTGTTGCTCACAGGGATCTCAAATCGGACAACGTGCTGTTGGAGTTTGACTCAGATGGTTGTCCTCGTTTAGTGATTACTGACTTTGGCTGCTGCTTAGCTCAGAGTGACTCTAAGCTACAGCTGCCCTTCAACAGCATGTGGGTCAACAGAGGAGGGAATGCCTCCCTAATGGCCCCTGAGGTGGCCACTGCAGTTCCGGGGTGGGGTGTGGTGATTGACTACAGCAAGGCAGATGCGTGGGCAGTGGGTGCCATCTCCTATGAGATATTCGGCCAGCCTAACCCATTCTATCGAGCAGTGGGACTGGAGAGCAGGAGTTACCAGGAGAAGCAGCTTCCTCCTCTGCCCTCCGGCGTTCCAGCTGATGTGCAGTTAGTGATCCAGTTACTCCTCAGGAGGAACCCAAGCAAGCGCCCCAGTGCCCGTGTGGCAGCTAACATGCTACATCTTAGCCTCTGGGGGCGGAAGGCCCTGGCCAACCAGGACAGCGTTGGCTTGAGGAAGCtggctgattggctgctgtgcCAGTCTGCTGTGGTTCTCCTGAAGGGCTGTAGTGGACTCGGGGGGAATATAGTGGAGGCGGAGCTTCAGAGGAGCTTCCTGTCTAACCTGGACCTGGAGGACCTGCGCACCGCTGTCGGCTTCCTACTGTACGGGCGAGAGCAGCGTCAGGCTTGCGTTCTATCTGCATAGATCCGCTCTCACTTATTCAGACAGATAGCTTAAGTTTGATATGGATAGACTGGGAGCCTTGTGTAGATTttcagttttacattttttgtaatcTTTATAGTCTTGGCCTTTTTAAATACAATGGCTATTAAGGCAAACTCCACTGACACTGTACTCCCACACTGTTGTACGTCATCTGTGACTGACATCAGCAGTTATTGTGAATTATCAAATGGTGTAATTCACCCCTAAAATAGTGCTGTCTATCGCTGCTAAAATTCCTGATCTGCATTTCCCAGCGTGTTGTCACAGACTCAGCGTCACCACAGCATCAGCAGGAGTTAAATAAAAGTGCTACTAGTGCCCCTTTATGCAAAATGCTTTTGTGGGTGCATGGCATCACAGACTATACAGGCTACTGTTGGTGGAGAAAAGACCTTGGTATCTCTGTGTATTCTAGGATTAAGTTTTCCCTAAATGAGTGTTGTTTGTCAGCAACAAACTACTAAATTGGCCCAGAAATGCAAGGTACCAATGGCTGCTGGTATTTGTTTATAAGAGTGGATATTTACTTTTACAAGCTCTGATGCACCTTAGATATTTGCTAAGAAAGACCCCACACTACAGTCGTTGTTACCTGTGTGTTTGATTAAAGTTGGTCTGTGTAGACGTTTTGGACTGATAAAGATGAAGGCCAAAAGCAGGTAGTTTTGCCTtatggccctgacacaccaacccgattttCGACTTTTTTGACCATCTCGGAgaggcagtcagtccgactgccttttctgctgaaGGTCGGCCGTCAGGTTGGTCTGTCAGAGCCTTTAGAGTAAAAAGTGCACACTGCACTTGTCAGACCCTACTGTGTAGGGTGACATTATGTTTTACATGTTCACAGGTAACATGCAGCCTTAGCTGTCAGCTAAAAACGTGTTGGGTGTCTGTGTGAGCCAAACAATCACTTATTCCCCCATTCTGCACATTGTAACGCATGAAAAATCCTCCCCAACATGTTACTACATTGTTATCACAATGATGATAGTAGATGGCATGGATCATGCAGTTTATTGATCGGCcgtagtttgttttgtttttgttcctgTGGTTTGCACTTTAAGTCCATGTTTGCACTTGCTAAGAGCCATTGTTGTGGCTTACCGGTGTTTGTGGCCAGCTTATCTATAATATCTATTATATTCTGGTAAattatttgaaaagaaaaaaaaaatgtcacactTCACTATGATCTGTTCTCAAAACTAGTCACAGTAAGCCTACAATGTTTGCTTGATAACATTATTAAATATCATAAGCACGTGGACAGTAGGGGATGCAAGATATAGAGTGTATATTTTAATACTGAAGATGGTGAGAAATACTTTGGATATATGTAGATTTTTCTGctgtttcagaataaaagtctgaaaaaaaGCA

Function

symbol description
pink1 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within several processes, including dopaminergic neuron differentiation; nucleate erythrocyte development; and regulation of vascular endothelial growth factor signaling pathway. Located in cytosol and mitochondrion. Is expressed in several structures, including digestive system; gill; heart; nervous system; and spleen. Used to study Parkinson's disease and early-onset Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Orthologous to human PINK1 (PTEN induced kinase 1).

NR:

description
serine/threonine-protein kinase PINK1, mitochondrial

GO:

id name namespace
GO:0051402 neuron apoptotic process biological_process
GO:0071542 dopaminergic neuron differentiation biological_process
GO:0060872 semicircular canal development biological_process
GO:0006468 protein phosphorylation biological_process
GO:0005829 cytosol cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005524 ATP binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
K05688 PINK1; PTEN induced putative kinase 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039800014.1 True 3267 mRNA 0.48 8 10118685 10131254

Neighbor

gene id symbol gene type direction distance location
LOC120558778 NA coding upstream 1850 10023340 ~ 10116835 (+)
fam43b fam43b coding upstream 119371 9996288 ~ 9999314 (+)
vwa5b1 vwa5b1 coding upstream 148762 9936549 ~ 9969923 (+)
LOC120559339 cptp coding upstream 200053 9916527 ~ 9918632 (+)
LOC120559338 NA coding upstream 214242 9901990 ~ 9904443 (+)
hspg2 hspg2 coding downstream 31748 10163002 ~ 10288140 (+)
tmem269 LOC103365731,LOC102791044,LOC104928629,LOC100689985,LOC100710458,LOC108237576,LOC101473555 coding downstream 172141 10303395 ~ 10316636 (+)
magi3a magi3 coding downstream 195494 10326748 ~ 10526334 (+)
LOC120559190 LOC103365742 coding downstream 399409 10530663 ~ 10540352 (+)
LOC120559192 NA coding downstream 443347 10574601 ~ 10583529 (+)
G48507 NA non-coding upstream 104302 10010836 ~ 10014383 (+)
G48481 NA non-coding upstream 197877 9920048 ~ 9920808 (+)
G48415 LOC103359731 non-coding upstream 314339 9803739 ~ 9804346 (+)
G48400 NA non-coding upstream 352290 9764056 ~ 9766395 (+)
G48399 NA non-coding upstream 366140 9752026 ~ 9752545 (+)
G48594 NA non-coding downstream 272798 10404052 ~ 10404759 (+)
G48602 NA non-coding downstream 380568 10511822 ~ 10542926 (+)
LOC120559193 NA non-coding downstream 412755 10544009 ~ 10560240 (+)
G48639 NA non-coding downstream 454905 10586159 ~ 10586543 (+)
LOC120558408 NA non-coding downstream 505222 10636476 ~ 10637645 (+)
ubxn10 NA other upstream 193604 9922600 ~ 9925081 (+)
G48347 NA other upstream 688738 9404224 ~ 9429947 (+)
LOC120559255 tshz2 other upstream 996773 8990487 ~ 9121912 (+)
G48162 NA other upstream 1392133 8716767 ~ 8726552 (+)
G48077 NA other upstream 1430721 8680282 ~ 8687964 (+)
agmat agmat,LOC102790280 other downstream 8344 10139598 ~ 10151251 (+)
G48640 NA other downstream 482777 10614031 ~ 10750428 (+)
G48752 NA other downstream 1041341 11172595 ~ 11173654 (+)
G48765 NA other downstream 1183408 11314662 ~ 11315992 (+)
xkr5l xkr7,LOC103354446,LOC100690518 other downstream 1953198 12084452 ~ 12090773 (+)

Expression


Co-expression Network