AMCG00001348 (als2,LOC106574246)


Basic Information

Item Value
gene id AMCG00001348
gene name als2,LOC106574246
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030137.1
NCBI id CM030137.1
chromosome length 27060302
location 26021981 ~ 26069510 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00001348
TTGCAACATCGCATGGGAAGGGCTTCACTTTCGCTATTATTTCAATTAGTTTATCTCACAAGAAGTGTTCCTCTCTACTGGAAAGCTGATGAATAACTTTTGCGACGGGGACTGAGCGGCAGATACCGAGCGGACGGGAGGGGAGTCTGTAATGTTTGACGTTGCTGGCTAATATGCAGTTTCAGTGACATGGAGAGGGCTTACTAATGGACCACCAGGAAAACAGTTCTAGAGAGGATGAGGGTTCTGGGGAGAGAGGTCTACTCCACACCTGGAAGGGCTATTCCTGTGGGATCGCGCCCCAGAGAGTGCTCCTGTCCAAGGTTGTACTGCAGGCGGCCCTGGGAACCCGGCATGGCGTGCTGCTGGCTGAGGGTGGCGAGGTGTACAGCTTTGGAGAGTTGCCGTGGAAAGTAGGCAGGGCCAATGAGGAGGCAGCCCCCGTGCTGGAGCAGGCCCTGTGCGGTCGGCACGTGGTTGCAGTGGCGGCCGGAAGCTTCCACAGTGGGGCGGTGTCCGAGGAGGGCTCTGTGTACATGTGGGGGGAGAACTCCTCCGGCCAGTGTGGGGTGGCCGGCCGGAGCCTGGTCCCTGAGCCCACGGCGGTTAGCATTTCAGACCCGGAGACCAGTCCGCCCCAGCTGATCAGGATCACGGAGCTGGCGTGCGGGGAGCAGCATAGCCTGGCGCTGTCCGCCCACAGGGAGGTGTGGGCCTGGGGCAGCGGCTGCCAGCTGGGCTTGGTCACCAGCGTCTTCCCCGTCTCCCGGCCCCAGAAAGTGGAGCACCTGGCTGGGCGACACGTGCTCCAAGTGGCCTGCGGGGCCTTCCACAGCCTGGCCCTGGTCCAGCAGACCCTGGCTCAGAAGGCCCGCCCACCCCCGGACAAGTGTAACCACTGCCATCAACTGCTCATCACCATGACCGACAAGGAGGATCACGTCATCATCTCCGACAGCCACTACTGCCCCTTGGGGGTGGAGCTGGCCGACGGCGAGACCCGGCACGGCTCCCCCGCCGCCCCCAAGCTCAGGAAGTCGCCTTCTGAACCCTTCCTCTCCAGCCCCCCCATTCTCCCGAAGGCCACCCAGCGATCGGTCCACCAAGACATCCAATCGGTTGAAGGCGTGCCGGCGGTGAAGGTGGAACAAGATGGAGAGTGCTTTAAAGAGGAAAACTCTGATGCAGACACAGATGGTAAAGCAGCGCCAAACACATGGGGCAAAAACTCCCCGTACCCCAATGAGCAGGCAGTCAAGGAGTATCTGAAGAGGTTGTCTGACTACTCCCTGGCCGAACAGGCCCCCAAAGTCCCTGGAGTTCAGGTTTCTCAGGAGCTGCCTGCCGACCCTGTGGTCCCGGAGGAGGTGCCTCCAGCCACCACAGCCAGCTCCACCCTCAACAGCCTGGTGGTGTCCTGCGCCTCTGCCGTGGGCGAGAGGGTGGCGTCCACTTACGAGGCCCTGTCCCTGAAGAAGGTGATGAGCTACTATTACCCATCGCCGGGGGCCTCGCCGGGGCCTCCGGAGGGTGCCAAGGAGACCCGCGAGGAGCAAGTGCGGCATGAGGAGTCCATGCAGGGCAAGAAGAGCTCCAGCCTGGGTGACATCCGTGAAGAGGAGGCCGAGGGGCTGAGTCGCAGGCTGTCCCTGCCTGGCCTGCTCTCTCAAGTCTCCCCCAGGCTGCTGCGCAAGGCCAGTCAGCCCCGGGTGCGGACGGTGGCCCTAACCCCCACCTCGGGCACGGAGGCTGACGGCCGTCTGCCCTCCCTGCACACAGAGGTGTGGAGTTGGGGCAGAGGCAAGGAAGGTCAGCTGGGCCACGGGGACATCCTACCCAGGCTGCAGCCTTTGTGCATCAAGAGTCTGAGCAATAAAGAAGTCATCCGTGTGGCTGTAGGAGCCCACCATTCTCTCGCCCTCACTGCCCAGTCTCAGGTCTTCTCCTGGGGCAGCAACACCTCTGGGCAGCTTGGTCACATGGAGTCCCCCACCACTGTTCCCCGATTGGCTAAGATGTCGGAGGGGATCCGCGTGTGGGACGTCTCTGCCGGGCAGCAGCACACCCTGTTGCTGGCGGATGGAGACTGCTACCAGCCCATCCTCTACTACAGTGGCAAACAGGTCAAAGAGCAGGACGGCAGTCCCCAGACCGAGGGGGGCTACACCCAGCAGCCTGTGCTTCTGCCCTTCTGCATGAATATGGGCTACGTGAGCAGCGTGTTTGCAGGGGGCCAGAGCTGCCTGGCACTGTCAGACAAGAACGTCATGGGCTTCATAGCCAGCCTGCATGAGCTGGCCTCGGCCGAGAGGAAGTTCTACTGCAAGCTGAGCAACGTCAAGTCTCAGATCCTGCGCCCGCTGCTGGGCATGGAGACGCTGTGCACCGCTCTGGGCACCGCCTGCAGCCTCCTGCTCCAGACTATGGCCAGCTGCTTCAGCAAGCTGTGTTACCTGACTGGGCAGCACTCGGCCTCCCTCAACACCTTCATCCGCCGCAGCAAGGAGGTGAAGGGCCTGgTACTGTAACTCGGTGGGGAATTTCCTTGTGATGGGGGGATTTCAAGCCCTGGCCAAACCCTCACTAGATTTCTTTGGCAAGAGCCCGGAGCTGCTACAGAGGCTTTCTGAAACCAACGATGAAAGCGTGCCTCTGTCTGACCTGCTGCTGACCCTCTTCTACCTTCCCATCAGACACCTGCACGAGTACGGCAGGGTGCTGCTCAAACTGGCCACCTGCTTCGAAGTGACGGCCTCAGACTATCAGAAGCTGCAGGACGGCAGCTCCAAGTACGAAGCGTTGGCTATCCATTTGAAAAGGAAGAGGAAAGAGGCGGAGTATACCTTTCATTTCTGGAAGACTTTCCCAGGGAAAATGACCGACTCTCTGAGGAAGCCCTCTCGCCGGCTTGTGTGTGAAAGCAGCAACAAGGCGCTGACCCTGCAGAACGCCGGGAGGTTCTCCGTCAACTGGTTCATCCTTTTCAACGACGCTCTGGTGCATGCACAGTTTTCCACCCACCATGTTTTCCCCCTATCCACACTATGGGTTGAGCCTATCTCCGAAGAACAAAGTGGCTTGTTTGGGCTGAAAATCACCTCCCCTGAAGAAACCTTCACTCTGTTGGCATCTTCCCCCCTTGAGAAGGCAAAATGGTTCCGGGCGATCAACCAGGCGGTGGAGCTGGCTCTGAGTGGGGCAGTGGACACCCCGGGCACAAGCTCAGCCAGTGTGCAGAGGCCAGATCCGCCCATGTCCAGGACGGCCAAGTACACCTTCTACAAGGACAGCCGTCTCAGAGAAGCCACCTACGAAGGCCGCTGGATGGCCGGCAAGCCCAACGGCAGGGGGATTCTGAAGTGGCCCGATGGACGGATGTACACCGGGACGTTTAAGAATGGCTTGGAGGACGGattTGGAGAGTATATTGTGCCAAACAAGACACTCAATAAGAATGACCATTACATAGGCCActggaaagaaggaaaaatgcATGGCTATGGTACCTACAGGTACGCCACAGGGGAGCTGTACGAAGGCTCCTTCCAGGACAACATGCGTCACGGCCATGGCATGCTGCGCAGCGGCAAgctcacctcctcctcccccagcgTGTTCATCGGCCAGTGGGTGCAGGACAAGAAGACGGGCTACGGCGTGTTCGACGACATCACCAGAGGTGAGAAGTACATGGGGATGTGGCAGGACGACCTGCGCCAGGGCCATGGAGTCATTGTCACGCAGTTTGGACTGTACTATGAAGGGGCcttcagcaacaacaaaatgatgGGCACTGGCATTCTCCTCTCAGAAGATGACACTACTTACGAAGGAGAGTTTTTAGATGACTGGACTCTCAATGGCAAGgggacTCTGACGATGCCCAACGCAGATTATTTTGAAGGCACTTTCAATGGAGAGTGGGGGACGGGCCTGAAGGTAGCAGGAACGTACTTCAAACCCAACCTGTATGACACTGACAAGGAGAAAGTGAAGAGTCTGAAGCTGGGCATCCTAGCGGTGCCTCCAGAGGAGAAGTGGAAGGCCGTTTTCGAGGAGTGCTGGAGCCAGCTGGGCTGCGAGGGCCCGGGGCACGGGGAGAACTGGAGGGCCTGGGAGAACATCGCAGTGGCCCTCACCACCAGTAGAAGACAGCACAGGGACAGCCCTGAGATTATCAGTCGCTCGCACAACAAAACCCTGGAAAGCCTGGAGGTCATTCCCCAGCACATCGGCCCCGTCACCATGGAGAAATACGAGAACATCCGCCGCTACTTAATCAAGgccTGCGACACCCCTCTGCACCCCCTGGGCAGGCTGCTGGAGACCCTGGTGGCTGTGTACAGGATGACCTACGTGGGAGTGGGAGCCAACCGCCGTCTCCTGCAGCAAGCCGTCAACGAGATCAAGTCCTACCTGCGGCGCATCTTCCAGCTGGTCAGGTTCCTGTTCCCTGATCTTCCAGAAGAGGGCGGAGTGATCCCGGAGCCCAGCGCCGAACCGCAGGACGGCAAAGTGCAGAGCGAGGAGGGAGCTCAAAACAAGGCAGAGTCGCCACAGCCTGCGCGCGTGGTGTCCAGCTGCGGGCTGCTGTTGCCTGTGCTGCTGCCCCGGCTTTACCCCCCACTGTTCACGCTGTATGCCCTGGAGAACGAGCGCGAGGAGGACATGTACTGGGAGTGCGTGCTGCGGCTGAACAAGCAGCCCGACGTGGCGCTGCTCAACTTCCTGGGGGTGCAGCAGAAATTCTGGCctgtttccatttcagttttggGAGAGAAAAAGCAGGTCCTGCCCAGTACAAAAGATGCCTGCTTTGCATCGGCCGTGGAGTGTTTACAACAAATCAGCACAACTTTCACTCCCTCGGACAAACTTCACGTCATTCAGCTCACGTTTGAGGAGATCACCCAGGAAGTGCTGGCGCTGCTGAAAGAGGACTTCCTGTGGTCGATGGATGACCTTTTCCCCGTGTTCCTGTATGTGGTGCTGAGGGCGCGAATAAGGAATCTGGGCTCCGAAGTGCATCTAATGGAAGATTTAATGGATCCTTGTGTGCAGCATGGAGAGCAGGGGATCATGTTTACAACACTTAAAGCTTGCTACTACCAGATCCAGCACGAGAAGATCACATAGGGTTTGAGGAGCATCTCTCCGAAGCTGCAATATGGGCACCACTGCAGCCAAGCAAAGCTCCTGGGCTCGGTTTGATACGAGAAGATGGAATCCTATTCTTAAACACTACTGGCCAACCCTTCAATGGGCAGATGCTGCTGTTGGTCTTGCGTTAAACAGTGAAGAGAGACCCTTCAGCAGGTTCTGGAAAAGGCAGGCCTTTTATCTCTCTGTCCCGGAGGAGACATTTGAAGGTCGTTTCAGTATCATCAAGGCAATGAAGGAACAGCTTTTCAATTCCCCCTTTTTGTTTCTCGAAAATGACTTGGTTTTAGTCATCCTGTTTGGTCAACATTGAAAAGCGCCCCACCCTCAGTCCAGGAAGGGGAATTCGGCTCTTTTCTTGTGGAGCACAGGTGATGTGGAGAAGCAGAAATGCAGTCGCTATGACATATTTACAATTCCCAACAGTCACAGCATTGGAAGGCAGTAGGATCTCTAAAAGTTTGAAAAGACGCCATCCTTTTGATTAAGCTTCAACCATAAGTTTGCccaatttaagaaaactaaccCAGGTCACCAATATAGGTCCTTATACAGGGGTGgtcttaaataatatattcattttgagGACTGGACTATACTCTGAATGATGGAATCTGTCTGCTGAGCAATAATTCCACTATTCCTGAAGAGGGCGTTATAATGCTGTAAACCTGCTGTAAAGTTTTAGAAGTACAGGTTGTATACATTGAGACCTCAGAGTTGTTTGTGTTGGTTGGTGTAGAGCAcatgtcatttttattgtgGCAACAGAGACTCCTAacttatatattaaattatattaatgatcCAGCAAAAACAACCGTGTTTGGTCTCGCTCCTTCTCAAAAGCAGTGCTCCGAGGCTCTGTTTTCCATGAGGGCCACTAGAAAGGAAATCTACCTGGACTTGTAAGATATACTTGACGAGATAGCAACCATTTTCAGTcagtgttttcagtttcatgTCCCAATTTAAAGTATTCCATATCAGTTAATATCCTCAAACTCAATTTTCTCAACTAACTaactaagaaataaaatgtatactagATGGGTTTTCCCTTGTTGTGGCCCATACTGCAACCTGTGAAAATCTCTACATTATCAGATCAAGATATGTTTGCTGTACTGTCCCCAAAAACGagtctgaatacaaaatatgtgcagatattttttgtgtgcatacCTTGCGTGGCCCATGACtttgtttaaacccttttttGAATCTGAAAAAGTTCAGGGACAATCAAACACGATTCAGAAGCATTCAGAAGTATCTgatgtaaaataattgaactGATGTATGAATATTGGTACAACCCTTACAAGTATtggaattacatttaattgaagcCTTTAAGGCCAATATTACTTAGTATATAGATACAAAATGAAGTTCATTATTGTACTTTCAGTCTGCTAAATGTACACTGTCAGAACAGCAGATGGTGCTATGATACTAAATCTAATCCATTCTTCCTGAAAATAGCAaaaccaatgaaaaataaagaaatagttCCATACATTTGAATGTTAGTATATTTccacaaataaaaatccaaGAGTCGAACTTTTTCATCTACAACGAAAAAACACGTATGTTTGGTATCACATGGTATGTgagaaattgtcaaatatatcattatttgtcaaatatatgggtatatgtatatttagatGAACAGGAAGGCATAATGTAATATGTTGCTTCTGGATTCCCATCCTGGTCATAATCACTAAATTGGATTTATTATCTTATATATTCATAgtttaaaactaatttcaagAAAGGGTTACTAACTTCTAAATGCTCACATTTGTGGTTTGGGTAACATTTTACACTGTGTccttaattactgtgtatttacactgtaattactttttatagTGTAAagacagtgtaaataggcataattacattGGTAGTTAACAAGTAAATTCACAGTATTTAgggacactaaatgtaaagtgttaccctagcACAGTAAAAAACATTGTAGCAATtcacaattacagtgtaaataggcataattacactggtagttaccaagtcattacactgtaaatacacagtaatcaGGGACAGTTAATGTAAAGTGCTACCGTGGTTTGATTTTGTGATCAAACTTCAATGACTATCTGCTCTCTCTTCACTCGATAGTTAACCCTAGAGTGGCCAAATGGGAATTTCAAATTTATTCTTTGATTTAATGGTAATAAactttgtatttacttttatttccttattgATCACTGAGTGAGTACAGTTCTCAGGCCCTCAGAGCACTGACATTGACACTGAAGGCCCCAAGCGATCAAAGTGCCACTATTGCTGGctggttgtttcttttttgacCTCTGTGTTGGAAAAGACAGTTTTTTCCTTGGTGGGAATATTCAACTGGACCCAAACGTACAAAGTATCTAGCATATGTTTTACTTGCATCAGTGAATGTATATAGACAAGATGAAATGTGGTTTTATGTTTCCTGTACACAAATTGTCTACTGATTATACcatgaacaaatacaatttcacagCCTTATCTTTGCCCTCTGTATTTGAAGCAGATTTCCCATGGCCCTTactttctctctgtatttcttTGAACACTGGCACTGTTGTTGGCAATGCATTGATCATGGTTGCCACCGGTCAACAGGAACTACTGCCTGTGGATAATTCACAGGCCAACTGTCTTGGCAGCAGGAGGCTCATTGATAGGGTGAGTTCAAGGCTTTTTACAGCAGTTGTCTACAGAATACTCCAGATCTAGGACTTCCAGGACTTATgaagaataatttattttgttactccTTTCAGCTCAGGACTCTAGTGGCAAGGGATTTCTGTCAGTATTCAACATCCCATTTGTCTGGACCGTATATCCTTGGACAGTATAAGTGGACATAATGCATCCACTACTGTTGTTCTCAGTTATGATTAAGTAgatattaatacacatttatttggcACATAGCACTAGATTGGTATTCATTTTGAAGGCATTTTGTGGTTGGAGAAAGTATTGGccattttcttatttaagtAACTTGATATCCCTACTTCTAGTAAATAGTCTGCTCGTCATTATATGGTTGTTACAGTCCTGGGGTTTTGTGAGAAAATGAAAGTGGAATGTGAACTAACAACATGtacttaaaatgttatattcaatatttcattGGTAGGGTTGTATTGTAATGATTTACAGAAAGGTCACTaatgaaacaaattacaaaatacaggcacaattgatttgtacatttgtttttgctttagcTTTTATTACCATACAAATACCTTCcaagttatttattaaataaaatctgaaattgcACTATTACGCTTTCTAcctattatataaaaataacgcaaacatataaatatataattaaaaaataaacaatgattctgtttaattaacaaatgtgaagtatttaatttaaaatccagtTATCATTTTGAAAGCTGTTGGTAGAACAAGTCTGGCAGAtgtttaagaaaactaaaaaggtGAAATGTAGGAAAGAAAGTGTCTtaagctttttatatatatgtatcaatttaaaattgaagtgtttttttggtggtgtgtgttttttttttcaccacttGATTCACCTGTACATTgaagacaaatgtattttggaATTCTAACGCTGATGATGCTTACagttggatttgtttttattcgaGCTCATTATAAAACTGATTATAAAAGTGTAGTGGCTCGTGTTTTGTTTCAAAGGTAATCTCTGTGTTGCTGAATGTAAAGATTGGTTTCACTCGAGCGAGACTGCTGTATTCAGATGCATCCATGAGACGTTCAAAGTGACTTCGATCACATCAAACATGTTCCTCAAAAGCAGCATCTTTTGTTGTTTATACTAagggtggattttttttttttgtatggttaCTGAAATCAATTAAACTAGATACCAGGCTGCACAAAACGACGAATTGGCCGCAGTGGGTGGTATTTTCCGGGAGCAGTTTAGAATAACATGGATGGTGGAGATTGACACTCAATTTCGAGAGAACCTACAAGAGTGTGTGCCGATGAAGCCGCTCCATTTTCAGGGTTTATCTGGCTCCTGTGGCAGGTGAATCTGCTTCCATTACTACTTCCCTGATTAACGAGCACAAACTCAGCTGCTGTCGTTCCTCAATTGAATGTGTCAGTCACCTCTGTGCCCTGAAAAAGTGTGCATCTTACATCTGtcttatctctctctttctctctgtctccatctatttatctctgtgtctctctctctctctctctctccaatcaGTAATCACACTGGCCTATGCGGACGAGGTTCTCTGCTCCCAATCATGCATTGGGAAACCGGTTTACTGTGTACTAAAAGGTATATAACATTGGTGTGTTGCCTTGCATACTGTGTCAATGCTCTTCTCTTCAGTCGTGAAAGAAAACCCAGCTTCAAGAACAGTTACCATCTTTTCAATACTAGAGTAATGTCGTTGGTGAGGGATACGCCCTGTTCCCTGACATCctgtattctttttttagtGTTCACAACAGGGGAAaagaatattaaatgtatatactaaAATCCCATTAAAATGAACAGTCTTAATATGAAGCAAgagtaataaaacatgaaaacaatgcTCTTTGGTGTGCTTTTCCTCTGTCAATGTTTTCCCAGTCCAGTACCTTTGTTCCGCATACTTGCCAATCCAGTCCGC

Function

symbol description
als2 Enables enzyme activator activity; protein homodimerization activity; and small GTPase binding activity. Contributes to guanyl-nucleotide exchange factor activity. Involved in several processes, including positive regulation of GTPase activity; positive regulation of protein kinase activity; and regulation of endosome size. Acts upstream of or within endosome organization; lysosomal transport; and protein homooligomerization. Located in several cellular components, including centrosome; dendrite; and early endosome. Part of protein-containing complex. Implicated in amyotrophic lateral sclerosis and amyotrophic lateral sclerosis type 2.

NR:

description
PREDICTED: alsin isoform X4

GO: NA

KEGG:

id description
K04575 ALS2; amyotrophic lateral sclerosis 2 protein

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00001348 True 9881 mRNA 0.48 34 26021981 26069510

Neighbor

gene id symbol gene type direction distance location
AMCG00001338 NA coding upstream 296302 25718904 ~ 25725679 (+)
AMCG00001333 NA coding upstream 348214 25663865 ~ 25673767 (+)
AMCG00001335 NA coding upstream 385642 25630047 ~ 25636339 (+)
AMCG00001334 NA coding upstream 440605 25552444 ~ 25581376 (+)
AMCG00001332 NA coding upstream 656685 25363893 ~ 25365296 (+)
AMCG00001350 NA coding downstream 6060 26075570 ~ 26097013 (+)
AMCG00001349 NA coding downstream 30768 26100278 ~ 26117478 (+)
AMCG00001351 NA coding downstream 53333 26122843 ~ 26140826 (+)
AMCG00001352 NA coding downstream 118379 26187889 ~ 26189870 (+)
AMCG00001347 LOC103029249,LOC108423993 coding downstream 161776 26231286 ~ 26268997 (+)
G130839 nol5,nop58,LOC106575044,LOC106594422 non-coding upstream 292144 25727853 ~ 25729837 (+)
G130817 NA non-coding upstream 346499 25675217 ~ 25675482 (+)
G130792 NA non-coding upstream 388405 25633234 ~ 25633576 (+)
G130789 NA non-coding upstream 439375 25582342 ~ 25582606 (+)
G130773 NA non-coding upstream 571123 25450516 ~ 25450858 (+)
G130948 NA non-coding downstream 227197 26296707 ~ 26335290 (+)
G131017 NA non-coding downstream 701370 26770880 ~ 26771161 (+)
G131021 NA non-coding downstream 723761 26793271 ~ 26793553 (+)
G131072 NA non-coding downstream 909265 26978775 ~ 26980289 (+)
AMCG00001337 sumo1 other upstream 272480 25735555 ~ 25749501 (+)
AMCG00001331 NA other upstream 571671 25423687 ~ 25450310 (+)
AMCG00001315 NA other upstream 1415509 24584179 ~ 24606472 (+)
G130616 si:ch211-114n24.6,LOC107581306,LOC108436424,LOC101061790,LOC103034569 other upstream 1567596 24433793 ~ 24454385 (+)
AMCG00001312 tuba4a,tuba8l4,tba1a,si:ch211-114n24.6,LOC108251627,LOC107714908 other upstream 1575748 24424565 ~ 24446233 (+)
AMCG00001361 NA other downstream 787089 26856599 ~ 26880797 (+)
AMCG00001365 NA other downstream 834853 26904363 ~ 26954597 (+)

Expression


Co-expression Network