AMCG00007306 (rag1)


Basic Information

Item Value
gene id AMCG00007306
gene name rag1
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030123.1
NCBI id CM030123.1
chromosome length 53548854
location 10739045 ~ 10743675 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00007306
ATGGCAGCGCCTCTGGCAGAAACCCCTTTGCGCTCCATGCCTGATGAGATCCAGCATCCCTACTCCAAGTTCTCTGACTGGAAGTTTAAGCTCTTCCGCATCAAGTCCATTGAGAAGGCTCCACTGGCCAGGGAGAAGGAAAACCAGCCGGCCCAGATAATTTTGGCACAGCCTCCCAAAGATGTAGAAATGTTGGGAGGTGAGACCCCCTCTATGGGTGTGATGAAGCTTTGCCTGGGAGGGAAGTCCAGGGAGAGTGTGGAAAACAATCGAGTAGACCTTAAGCTTGTGGAGATAGAAACCCACATGGCTCGCCTGAGGTGTCTTTGCAGACTTTGTGGAGGACCTTTAAAAAGAGGCAAGGCCAACCTGGAGTATGAGGTACAGGGAACTTTGGATGATGTGAGCCGAGAAGCTCTGAGGAAAATGGGCTGTAAGGCCCGAGGCTGGCCAGAGGTTATCTTGAAAGTCTTCAAGCTGGACGTGACTGGAGACCTGGAGACAGTCCACCCAGCCTTCTTCTGCCACAGCTGCTGGAAAGCTGCGATGCGAGGAGGAGGCTTCTGCTGCTTCTCCAACACCCAGGTCCCCCAGTGGAAGCCTCATTCTGCCTTCTGCAAGCTGTGCTCTCAGACTGTGCTTTCCCTTAAACGGAAGCGCAAGTCCCCCAGGTCTCAACTGGCCAAGCGAACCAAGTCAGATTTTGGTGAACGCAGTGTCAGGGGCCGGAAATCCAAAGACCAGGGCAAGCCCAAGCCCAAGCCTAAGCCTTGGACCAAAGTTCACATCCAGAGAAAATTCTGGGTAAAGAATATAACCTGCTGCAAAAGCATCCACCTCAGCGCCAAACTCCTATTGGTGGACTACCCTGTTGACTTTGTCCGTTCAGTCACCTGTCAGGTATGTGATCATTTGCTAGCAGAACCCGTCCAAGCATCATGCAAGCACCTCTTCTGCAGGGCTTGCATCCTGAAGTACATCCGTGCCCTGGGGACCCACTGCCCCGCCTGCCATGTCCCCTGCATTCCCTCCGATCTGGTGACTCCAGCCAAGGCTTTCATGGGGGTCCTCAATTCACTAGTGATCCGATGCCCGGCCGAAGGCTGTCAGGAACAGGTGCGGCTGGAAGATTATTGGGCGCATACCCTTTGCCACCAAGAGAGCCAGAGCAATGACATATACTTGCCTGTCAATAAGGGAGGGAGACCAAGGCAACACCTGCTCTCACTGACACGCAGAGCCCAGAAACACAGGCTGAGGGAGCTGAAGAACCAGGTGAAGGCGTTTGCCGAGAAGGAAGAAGGAGGGGACATCAACCAATACCACAAAATGTACCGTACTGTTAAAGCAACCAGTGGCAGACAGATCTTTCAGCCCTTACACACCCTCCGAAATGCAGAGAAAGCCTTGCTTCCAGGATACCATCCCTTTGAGTGGCAGCCGGCATTGAAGAACGTGTCCAGCAACACAGAGGTGGGGATTATAGATGGGCTGTCTGGCTGGGTGGCTTCTGTGGATGACCAACAGATCAACACCATCTCCCGCAGGTTTCGCTATGATGTGGCTCTTGCCGCTGCTTTGAAGGACTTTGAAGAGGACATTGTGGAAGGCATGAGGGAGCAGCAGCTGGATGACAGCTTGACTGAGAGTTTCACTGTGATCATCAAGGAGGCTTGCGATGGCATGGGAGACGTCAGCGAGAAACATGGGAATGGCCCAGCTCTTCCTGAGAAAGCTGTCCGCTTCTCCTTCACCATCATGTCTATTTCCGCCCACAGTGAAGATGGGAAAAATGTCAAGATCTTCCAGGAGCTCAAACCTAACTCAGAGCTCTGCTGCAAGCCCCTGTGCCTTATGTTCGCGGACGAATCTGACCATGAAACGCTGACTGCTATATTGGGGCCTGTAGTGGCTGAGCGGGAAGCCATGAAAGAAAGCCGCTTGATCCTTTCAATTGGGGGCATGCTGAGGTCCTTCCGGTTTGTGTTTAGGGGCACAGGCTATGATGAGAAATTGGTCAGAGATGTGGAAGGACTTGAGGCTTCAGGGTCTACTTACATCTGCACCCTTTGTGATTCCACCAGAGCAGAAGCTTCTCAGAATATGGTGCTGCACACAATCACCAGGAGCCACGAGGAGAACCTAGAACGCTATGAGATCTGGAGGACCAACCCATACTCAGAGTCGGCCGATGAGCTGCGTGATCGGGTCAAAGGGGTTTCAGCAAAACCGTTCTTGGAAACGTTGCCCTCCATCGATGCGCTGCACTGTGACATCGGGAATGCCACCGAGTTTTACAAGATCTTCCAGGATGAAATTGGAGAGCTCTACATCAAAAGCAACCCCACCCGGGAGGAACGGAAGCGGTGGCAGTCTGCCCTAGACAAGCAGCTGAGGAAGAAGATGAACCTTAAGCCCATCATGAGAATGAATGGCAATTTTGCCCGCAAACTGATGACCAAGGAGACGGTGGATGCTGTGTGTGAGCTGGTTCCTTCTGAGGAGCGCCGAGAAGCTCTCAAGGAGCTGATGAATCTCTACCTCCAAATGAAACCTGTTTGGCGCTCCACCTGCCCAGCCAAAGAGTGTCCTGACTTGTTGTGCCGCTATAGCTTCAACTCGCAACGTTTTGCCGAGCTCCTATCTTCCACCTTCAAATACCGCTACGATGGCAAGATCACCAATTACCTGCACAAGACCCTCGCTCACGTGCCTGAGATCATTGAGAGGGATGGATCCATTGGGGCCTGGGCCAGTGAGGGCAATGAGTCAGGGAACAAGCTCTTCCGTCGCTTCCGCAAGATGAATGCCAGGCAGTCCAAGTGTTACGAGCTGGAAGATATTCTCAAGCACCATTGGCTCTATACCTCAAAGTATCTCCAGAAGTTCATGGAGGCTCATAAGAACTCAGCTAAGGCTTTTGAAGCCACCATCAATCCAGTGGAGACCCCGGAGGATGAAGCTGAACTCATGGAGTCTCTGGTGTTTTGA

Function

symbol description
rag1 Enables magnesium ion binding activity and sequence-specific DNA binding activity. Contributes to double-stranded DNA endodeoxyribonuclease activity. Acts upstream of or within V(D)J recombination and protein-DNA complex assembly. Part of DNA recombinase complex and endodeoxyribonuclease complex. Is expressed in gonad; hematopoietic cell; hypophysis; immune system; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in Omenn syndrome; combined cellular and humoral immune defects with granulomas; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive. Orthologous to human RAG1 (recombination activating 1).

NR:

description
recombination-activating protein 1, partial

GO:

id name namespace
GO:0033151 V(D)J recombination biological_process
GO:0010390 histone monoubiquitination biological_process
GO:0090305 nucleic acid phosphodiester bond hydrolysis biological_process
GO:0030183 B cell differentiation biological_process
GO:0033077 T cell differentiation in thymus biological_process
GO:0005634 nucleus cellular_component
GO:0042393 histone binding molecular_function
GO:0043565 sequence-specific DNA binding molecular_function
GO:0004519 endonuclease activity molecular_function
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K10628 RAG1; V(D)J recombination-activating protein 1

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00007306 True 2991 mRNA 0.53 2 10739045 10743675

Neighbor

gene id symbol gene type direction distance location
AMCG00007305 NA coding upstream 71750 10660181 ~ 10667295 (+)
AMCG00007308 NA coding upstream 84056 10628350 ~ 10654989 (+)
AMCG00007304 NA coding upstream 130030 10577246 ~ 10609015 (+)
AMCG00007303 NA coding upstream 161881 10534157 ~ 10577164 (+)
AMCG00007300 LOC106562579,LOC106593862,LOC106597634 coding upstream 318134 10394165 ~ 10420911 (+)
AMCG00007310 NA coding downstream 15159 10758834 ~ 10777707 (+)
AMCG00007311 NA coding downstream 844959 11588634 ~ 11603718 (+)
AMCG00007317 NA coding downstream 2798081 13541756 ~ 13551121 (+)
AMCG00007321 mrpl21,LOC106561938 coding downstream 2879469 13623144 ~ 13624807 (+)
AMCG00007322 NA coding downstream 2902952 13646627 ~ 13647013 (+)
G22652 NA non-coding upstream 53977 10626674 ~ 10685068 (+)
G22596 NA non-coding upstream 417187 10320469 ~ 10321858 (+)
G22528 NA non-coding upstream 497637 10152489 ~ 10241408 (+)
G22417 NA non-coding upstream 1094298 9642597 ~ 9644747 (+)
G22373 NA non-coding upstream 1246378 9488712 ~ 9492667 (+)
G22712 NA non-coding downstream 367668 11111343 ~ 11111723 (+)
G22720 NA non-coding downstream 486150 11229825 ~ 11230393 (+)
G22730 NA non-coding downstream 768478 11512153 ~ 11522358 (+)
G22738 NA non-coding downstream 797308 11540983 ~ 11541524 (+)
G22741 NA non-coding downstream 827277 11570952 ~ 11573862 (+)
AMCG00007307 clg19h11orf96 other upstream 125941 10611196 ~ 10613104 (+)
AMCG00007278 NA other upstream 773778 9936920 ~ 9965267 (+)
G22372 NA other upstream 1239317 9436524 ~ 9499728 (+)
AMCG00007253 calcb,LOC106584617,LOC104951332,LOC107090894,LOC106922915,LOC106950942,LOC103461098 other upstream 2027734 8697983 ~ 8711311 (+)
AMCG00007242 NA other upstream 2287463 8431102 ~ 8451582 (+)
AMCG00007337 NA other downstream 3734998 14478673 ~ 14489692 (+)
AMCG00007352 NA other downstream 4533036 15276711 ~ 15287960 (+)
AMCG00007350 tsg101 other downstream 4622986 15366661 ~ 15379965 (+)
AMCG00007379 NA other downstream 5880715 16624390 ~ 16662700 (+)
AMCG00007417 NA other downstream 7454943 18198618 ~ 18201960 (+)

Expression


Co-expression Network