AMCG00014186 (clcn4)


Basic Information

Item Value
gene id AMCG00014186
gene name clcn4
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030128.1
NCBI id CM030128.1
chromosome length 42883965
location 3617227 ~ 3629082 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00014186
CGCCGCGGTGCATTGTGGGGGCTCTCCGCCGCGGTCGGAGGATGTATACGACTCGTCCTATACTTCGCCTTAGAAAGCCTTAAGCACTGGTGCACAGTTTAGTTATAATGACTTAGTTTGCAGAAAAAACATCGTCTCTAAAAGCAGATTGTATTTATTCCAGGAAGATGGCGTCAGAAGTCCAACCTGACATGGTCTCCAATGAGGAGATGAATGGGTCCAGTAACCTGATGGACTTCCTGGACGAGCCGCTCCCTGATGTGGGCACCTACGAGGACTTCCACACCATCGACTGGCTGAGGGAGAAATCCCGGGACACGGACCGGCACAGGAAGATCACCCATAAAAGTAAAGAGTCCATCTGGGAGTTCATCAAAAGCCTGCTGGACGCCTGGTCGGGATGGGTGGTGATGCTTCTCATCGGGCTTCTGGCAGGTACTCTGGCCGGCGTTATCGACCTGGCTGTCGATTGGATGACGGACCTGAAGGAAGGGGTGTGTCTGTCAGCGTTCTGGTACAGCCACGAGCAGTGCTGCTGGACCTCCAACGAGACCACCTTTGACGACCGGGACAAGTGCCCCCAGTGGCAGAAGTGGTCAGAGCTGATGATGGGCCGCGCAGAGGGCGCTGGCGCATATCTTTTGAACTACTTCCTCTATGTGTCCTGGGCCCTGTCCTTTTCGTTCCTGGCCGTCTCTCTGGTGCGCGTATTCGCACCCTACGCCTGTGGCTCTGGCATCCCTGAGATAAAGACCATCTTGAGTGGCTTCATCATCCGGGGCTACCTGGGGAAGTGGACGCTGCTGATCAAGACGGTGACCCTGGTGCTGGTCGTGTCCTCGGGCCTCAGCCTGGGCAAGGAGGGGCCGCTGGTCCATGTGGCCTGCTGCTGTGGAAACCTCTTCAGCAGCCTCTTTGCCAAGTACAGCAAGAACGAGGGGAAGCTCAGAGAGGTGCTGTCTGCTGCTGCGGCCGCGGGGGTGTCTGTGGCTTTCGGAGCGCCGATCGGAGGAGTGCTCTTCAGCCTGGAGGAGGTGAGTTACTACTTCCCTCTGAAGACCCTGTGGCGCTCCTTCTTCGCTGCGCTGGTGGCGGCCTTCACCCTGCGCTCCATCAACCCATTCGGCAACAGCCGGCTGGTGCTGTTCTACGTGGAGTACCACACGCCCTGGTACATGGCTGAGCTGTTCCCCTTCATCCTGCTGGGCGTGTTTGGGGGCCTGTGGGGCACCCTGTTCATCCGCGGCAACATCGCCTGGTGCCGCCGGCGCAAGACCACGCAGTTGGGCAAGTACCCCGTGCTGGAGGTGATCGCTGTGACGGGCATCACGGCCGTGCTGGCCTTCCCCAACCCGTACACGCGGCGCAGCACCAGCGAGCTCATCTCGGAGCTGTTCAATGACTGCGGCGCGCTCGAGTCCTCGCAGCTGTGCGACTACATCAACGACCCCAACATGACGCGGCCCGTGGACGACATCCCCGACCGGCCCGCCGGCCCCGGCGTCTACACTGCGCTGTGGCAGCTGACCCTCGCCCTGCTCTTCAAGATCGTCATCACCATCTTCACCTTCGGCATGAAGATGGCGTACCACCATCACGACTGGATCATCTTCAAGAACTGGTGCCGGCCCGGGGCGGACTGCGTCACCCCGGGGCTGTACGCCATGGTCGGGGCCGCGGCTTGTCTGGGCGGGTCGACCCGGATGACCGTGTCCCTGGTGGTCATCATGTTCGAGCTGACGGGGGGGCTGGAGTACATTGTGCCGCTGATGGCCGCCGCCGTCACCAGCAAGTGGGTAGCGGACGCCTTCGGGAAGGAGGGCATCTACGAGTCGCACATCCAGCTGAACGGCTACCCCTTCCTGGACGTGCAGGACGAGTTCACGCACCGCACGCTGGCCACCGACGTGATGCGGCCGCGGCGCAGCGAGCCGCCCCTGGCCCTGCTCACCCAGGACAGCACCACGGTGGAGGACGCGGAGGCCCTGATCAAGGACACCGACTACAACGGCTTCCCCGTGGTGGTGTCCCGAGAGTCGGAGCGCCTCATCGGCTTCGTGCAGCGCAGGGACCTCATCCTGGCCATCAAGAACGCGCGCCAGAAGCAGGACGGTGTGGTGAGCAACTCGGTGGTCTACTTCACAGAGGACGCCCCCCAGCTCCCGGCCAGCAGCCCCCAGCCCCTCAAACTGCGGCGCATCCTCAACCTCAGCCCCTTCACCGTCACCGACCACACGCCCATGGAGACGGCGTCTCCTGGGTATCATCACGAAAAAGGACGTTCTGCGGCACATGGCCCAGATGGCCAACCAAGACCCGGAGTCTATCATGTTCAACTAGTCGGCGTGGGCGGGAGCGCGCTTTCCCACCGCCTCCCAGGATTCGCGATCGTGGACTGAGAGAGCCTGAGAACCGGGGCGGGGAGACGGGGACTCAGGAAACATGAACGGCTCCTGATGTAGAAGAAGGCCCAgaggcggagagagagagagaggggaagagcgTGGAGGAATGGACCAGCAGAGGAGAAGAGCATGCCTCTGGGGCTGGCTGTGTCTTTGTTGCTGCTCTTCTATGTGTCATGCACAGctggtttgttttctgaagaCGTTACGGCAGAAACTACTGGCTTCAAGAGTTCTGACTGGAAATTGTCTTATCATCGCTACCCCCTGCTGCTTCCCAATTGTCTTTACTTTTTGTGGACAGGTAGcattattttatacacactCCATCTCAAGGGGACTAGCTATATTCGTGCAGTTGTATCGATATCACAATGATTGGCACGCATACTTTTAATTGGAGAATCAGTGcctaaaattatgtattaaaacaaaaatgaatgcgCGGAAATTTGGGCAGCATTGTGAACCTGACCGTGTCAGCTGCGTGCGTTTCTTTTTGATCCAGTACcatcattatttaatgtttgggagaaataaatatatatatatatatatatatatatattatataataagcATGTTGCAGAAACGCACCATGGTGGActgaattaaatacacaaatattgcTTTCATGGTTTGACAATGTGGCAGGATTTGTATTGAATGACAGAATACTATCAATctgttatttgtataaataGGACTGCTATACAAACCTGGCAGAAGCAgctaattaataaaacaatttgacaCACTTATGACACCCTGCTGCAACAAACCCATTCGGTTTAACACCTGAACCACGTTGTGTTGTGCAGGTGAACCTGTGTCACTACCTTGTGTATCCGCAGGCCACAGAGCCAAGTTAAAATGGGCCTTAAATTCTGTTAAGGCCCAAGAATCCCAAAAATTTGAAAAGTATTTGGTTGTGTGTGCAGTAGGTCCATCTTGTGAAACATGTTACTAATGTGGAagttctgttttttatgttttttcaatcTGCATCTTGTGTGGATAATGGTTGCTAACTTATGAATTAATTTTACCTGCCAATAACTACATTTACGTTAAGATTTGTGGAATTTGCACATTTGATCAATATGTAAGTAGATGTAAGGAAATTGGAAAATATTTGCacaatatttgtctttttttgttgtttgtcattCCAGATTTTCTCTAATTGTAGGAAAATGCATCAATATCTATATACAGTTATACTTAACTCTTAGTTTGCACTAAAATATCTTTAATCATTAGCAATGAATGGAATGGTGAAATGCGTCGAACGTATGTTAGTGCGTCTCATCGGGGAACTTCCTGTCAAAGGTGTCCTCGTACAGGAAGTATGATTTGAAGAAAACTATACAGAGTTTATCGTTTTACAAATGCAAGTATCTTGGTCCAGTTTTTGGTGGGCCAGACACCGTTTTAGGAGGAAAGTGTGGAATTTGTAAACCTAGATGAATTCTCAAGTgtcaaccaaacaaaacaaaatgcagacaaACGAAAAAACTGGGATAGCGAGTTTCCCAGATAAGAGTTTTTTGGCAGTCTGTCCCCAGCAAACGTCCCGTGCTAATGTGAAGTGGCGTCCCAGCTCTCATGTCTGCTGTATCACGGGCAGGCCGGGCCCGCAGTCTGACAGCATGGACGCCACGGCACGAGGAGGCTGTGCGGCGTGGGCAGTGATAGTGCTGAGGCAGGACCTTCACGGTGTCCGCTGCACTCAGACGTCTTTCTAAAGTTGGGAAAAGAACATGGACTTGACAGTTTGCTTTAGAGGACATAACCGCACTTGACTTGCACAGCTTCTGTCTTCTCTGATCAGCTGTGTGTGGTGTGAGACGGCATCAAGATACTggtatttgaaattaataaacctACATGCACACAGCCTCGGCATGTGATACAGGCCTTCATCTCAAAAGTGTGTGTAGAACAGACCTTCTAGAAAGAAAATCAAGCCCTCAAATTCCCTCCACTGTCTCTGAATATACAGTGTAGCGTTTATTATTGATGGTTTTATCATTGTGGATTCTATAGAACATTTGTATAGTTTAGAAGGATACGGATATTGAATGGCAAGTTGGTCCTTGAAAGCTGTATTTCGGTAGTTGCAGCTCTAGATACTCTCAGATGAAACCTACTTGGAGTAATGAGACCCCAGCATAATATTTCAAGGATTAAAATGTTCTAAAACAGTAGGAGAATAAATATGAAGGTAGATGAAAAGCACTCAATGGACATAACTGGAAGTGTATTCCAAGAAATGTTTGTCttgatgtgaaaatgttaacaattCTGTAAACCTGGTTAAGAAAACCTCATTACTGAAAACTCCCCTGTGTTATATGTTGCTGCACAGTCACTTACTCGAAGGACAGTTCTTTATATAGGTGGAGACCactaaaaccttttttattttatgtctgtgAGTCACTAACCAGGTCAAATCTGAATCTGCTGCTCAGTGCACTTGTactaacttttttattattccctTTTCAACATCGTCTTCAACTGTTCAATGCAGTTTTCTTATAGTCTGTTACATGAGACCAGAAGCAAGTTTTTGCTGCCTTTGGGTCCCTGGGGAGGTGAAGCGCATTCCCGGCAAAAGCATGATATGAATGAAACCGCCACTAGTAGCGTGGTCTGCAAAGGGGATCATGTGAGACCTTTGTTGCCACATTACTAAGAGTAAAGGTTATCTGTcttaagtttgttttaaatggataTATTCTACAAGACGTTTTAATATACAGGAAACGTCATTTCAATCTTAATCATCCACACCGAGGAGTATCTGGTGTTCATACTGTGTACCCATCATGAAGTTGACCTGATTAGCCATGTGCTCCACTAACATGTTACACAGTACCTGACATGACACAAACACCTTTTAacactcttattattattatgattattagacTGAAATAATGGTTTTCCAGTTAAACACTGGAACTGACTCAGTAGATGTAACTTTTGTGGCgggatttaatatatattaattaacaaaatggcCACTGTTAGAAACCCCTCCCTGATTCATGAATAACGAAGTGGGATTTcaatcattgttttttaaaatactagTATTTATTGATTGTGGTCACGGCTGCTTGTCTTGATATATGTGCATTAGAGTACATTGTGTAAGAAACCGGTTGTACCATAACGTTGTGTTCAATAAAAGTTTAACTGCCA

Function

symbol description
clcn4 Predicted to enable solute:proton antiporter activity and voltage-gated chloride channel activity. Predicted to act upstream of or within chloride transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus; early endosome; and synaptic vesicle. Predicted to be integral component of plasma membrane. Is expressed in brain; eye; gill; heart; and immune system. Human ortholog(s) of this gene implicated in Raynaud-Claes syndrome. Orthologous to human CLCN4 (chloride voltage-gated channel 4).

NR:

description
PREDICTED: H(+)/Cl(-) exchange transporter 4

GO:

id name namespace
GO:0034765 regulation of ion transmembrane transport biological_process
GO:1902476 chloride transmembrane transport biological_process
GO:0044070 regulation of anion transport biological_process
GO:0016021 integral component of membrane cellular_component
GO:0030554 adenyl nucleotide binding molecular_function
GO:0005247 voltage-gated chloride channel activity molecular_function

KEGG:

id description
K05012 CLCN3_4_5; chloride channel 3/4/5

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00014186 True 5621 mRNA 0.49 12 3617227 3629082

Neighbor

gene id symbol gene type direction distance location
AMCG00014187 NA coding upstream 2146 3595095 ~ 3615081 (+)
AMCG00014188 NA coding upstream 34282 3582619 ~ 3582945 (+)
AMCG00014183 NA coding upstream 57518 3558918 ~ 3559709 (+)
AMCG00014182 NA coding upstream 62493 3527017 ~ 3554734 (+)
AMCG00014184 NA coding upstream 105569 3489479 ~ 3511658 (+)
AMCG00014192 msl3,LOC106574410 coding downstream 304176 3933258 ~ 3950277 (+)
AMCG00014194 NA coding downstream 417889 4046971 ~ 4081904 (+)
AMCG00014195 prps2 coding downstream 459281 4088363 ~ 4098941 (+)
AMCG00014197 NA coding downstream 477102 4106184 ~ 4118772 (+)
AMCG00014199 NA coding downstream 576073 4205155 ~ 4220124 (+)
G68189 NA non-coding upstream 133578 3410978 ~ 3483649 (+)
G68167 NA non-coding upstream 241438 3375585 ~ 3375789 (+)
G68166 NA non-coding upstream 242079 3374837 ~ 3375148 (+)
G68153 NA non-coding upstream 389101 3226859 ~ 3228126 (+)
G68151 NA non-coding upstream 390728 3224574 ~ 3226499 (+)
G68292 NA non-coding downstream 325284 3954366 ~ 3955265 (+)
G68317 NA non-coding downstream 454681 4083763 ~ 4083964 (+)
G68374 NA non-coding downstream 664244 4293326 ~ 4293526 (+)
G68376 trappc2 non-coding downstream 665735 4294817 ~ 4295819 (+)
G68422 NA non-coding downstream 871782 4500864 ~ 4550002 (+)
AMCG00014146 NA other upstream 906898 2706840 ~ 2710329 (+)
G67896 NA other upstream 1487082 2126872 ~ 2130145 (+)
AMCG00014111 NA other upstream 1714540 1900220 ~ 1902687 (+)
G67801 NA other upstream 1736186 1879091 ~ 1881041 (+)
AMCG00014104 cyyr1,LOC107751099 other upstream 1779102 1835432 ~ 1838125 (+)
AMCG00014196 NA other downstream 498394 4127476 ~ 4131718 (+)
G68475 NA other downstream 1020118 4649200 ~ 4651964 (+)
G68830 NA other downstream 3717113 7346195 ~ 7349467 (+)
G68848 NA other downstream 3784558 7413640 ~ 7416594 (+)
AMCG00014272 tbc1d23 other downstream 3835421 7464503 ~ 7482560 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_004382 clcn4 coding NC_007122.7 CM002895.2 44144612 ~ 44163164 (-)