AMCG00014707 (kdm6a)



Basic Information


Item Value
gene id AMCG00014707
gene name kdm6a
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information


Item Value
chromosome id CM030128.1
NCBI id CM030128.1
chromosome length 42883965
location 27717966 ~ 27762413 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence


>AMCG00014707
ATGTTCTCATTCCTCTTTCCCAGGGCGATTAAAGCATTTCAGGAGGTGCTTTACATTGATCCCAGCTTCTCCCGGGCCAAGGAAATTCATTTACGACTTGGGCTGATGTTTAAAGTTAACACAGACTACGAGTCAAGTCTAAAGCATTTTCAGCTGGCTTTGATTGACTCAAACCCCTGCACTTTGTCCAAAGCTGAAATTCAATTTCACATCGCGCATTTGTATGAAATTCAGaaaaaaTACCGCACTGCAAAAGAAGCGTATGAAAACCTTTTGCAGACAGAAAATCTTCCTGCACAGGTGAAGGCAACTACCCTGCAACAATTAGGCTGGATGCATCACACAGTGGATCAGTTGGGAGATAAAGCCAATAAGGAAAGCTATGCTATTCAGTGTCTGCAGAAGTCTTTAGAAGCAGATCCAAACTCTGGACAGTCTTGGTACTTCCTTGGCAGGTGCTATTCGAGTATTGGAAAGGTTCAGGATGCCTTTATTTCTTATAGGCAGTCGATTGATAAATCAGAAGCCAGTGCAGACACGTGGTGTTCTATAGGTGTGTTGTATCAGCAGCAGAATCAACCGATGGATGCATTACAGGCCTATATCTGTGCTGTCCAACTGGACCACAGCCACGCTGCAGCCTGGATGGACCTGGGCACCTTGTACGAATCCTGTAACCAGCCTCAGGATGCcattaaatgttacattaatgCAACAAGGAGCAAATCGTGTAGTAATACCTCTGCCCTCACATCCCGGATTAAATACTTACAGGCTCAGTTGTGTAACCTTCAACAAAGTAGTCTACAGAGTAAAACTAAAATGCTTCCTAGTATTGAGGAAGCATGGAGCCTACCAATCCCTGCAGAACTTACCTCCAGACAGGGCGCGATGAACACAGCGCAGCAGGCCTGTAAACCTCATCAGAATAATGATGTAGGCCTTGGACAGCCACAAATGCCCCAGCAGTCATTGCCTCTACACATGGCTCCTTCTGGCCAAGTAGATGATCAATCCAGTCCTGCCAAGAGAAAAAGAACATCAAGCCCAACCAAGAATACTCCAGATTCCTGGGCAAGCAGCCACACTGTTTCAAACAATCCAGTACAACAGCAAGTTCCTAACTGGTACTTAACACCACCGAAGTTACAGCTTCTGGATCAGTTACGGACTAACAGGCAAAACCTGAAGCCAGTTCAGCTGCAGATGTTGGAACAGCTGGAGGGGCAGTTTGCTTTGAtgcagcagcaccagcagcagATGAGACAAAATGTCGGACAGGTGCGACCAGCTGCTCTTCCGAACGGGCCAACTGTCGACTCTTCACTGCCTACAAACTCGAACTCTGGTTTGCAGCCCCACGTGGCTCTGGCCAGAGCCCCAAATGTCCTGCAGCCTGCAGTGCGGCCGGCATCTTCTGGCCAACCACTCGCCAACGGACCTTTCCCAGCAGGCTCTGCTCCCTGCAGCACAGCTGGAATGCTGGGTAACACAGACACTATTTCTGTAGGCAATAATCACACGACAGGAATGGGAAGCAACGGAAACGTGCCTTACCTGCAGCAACACGCACTAAGTCTACCTCATAACTGCACAAACCCgaccagcagcagcaacagcgaCGCAGAGGAGCCGTGGAAAAACCAACACGTTAACTCCACTCAGGTGATGGCAGATGCTGTTTCAAGCCCTAGCCATGGAGAATCCAAGTCACCAGGTGTACTTAGTTCAGACAATCCTCAGCTCTCTGCCTTGTTGATTGGAAAAGCCAATAATATCGGGGCTCCCGGGGCCTGCGAAAAAGTCAATAACGTTCACCCAGCCATTCACGGCTCAAAGACTCAAGAGAACTCTGTTGCCTCTTCGCCCTCCTCAGCCATGTCCACAGCCACTCCTTCTCCCAAATCAGTGGAACAAACTACCACGAACAGTGTTACCAGCCTTAACAGCCCTCCCAGTGGATTGGGGCATACAGTGAACGGAAAAGGCCTGGAGGACTCCCAAAGCCCCATGAAAGTAGACCCTCCCACAATCAGCCACAAACCCAACCCTCCACTCACACCGTCATCCTCAGTCTCCATTTACCCCAGCTCTACTGAAGTACTCAAAGCATGCAGAAACCTGGGGAAGAATGGTCTATCAAATAGTAGCATTTTACTAGACAAGTGTCCACCCCCCAGACCGCCACCTCCACCCTTCCCTTCGCTGCCAAAGGACAAACTCAACCCTCCAACTCCCAGTATTTACCTGGAGAATAAGAGAGACGCTTTCTTTCCACCTTTACATCAGTTCTGTACGAATCCTACAAACCCCGTCACCGTAATCCGAGGCCTCGCGGGAGCTCTTAAACTAGATCTAGGTCTGTTCTCTACCAAGACCCTGGTGGAAGCCAACGCTGATCACCTGGTGGAGGTGCGGGCACAGCTGTCGCAGCCTACTGATGAGAACTGGGACCTAACTGGAACTAGGAAAATGTGGCGCTGTGAAAGCAGCAGGTCACACACCACCATTGCCAAATATGCACAGTACCAGGCCTCCTCATTCCAGGAGTCACTACGGgaggaaaatgaaaagaaaggtcACAAGGACCATTCTGACAATGAATCGACATCCTCCGATAATGTGGGGCGACGAAGGAAAGGACCTTTTAAGACCATCAAGTTTGGGACAAACATTGACTTATCGGACGAGAAGAAGTGGAAGTTGCAGCTCCATGAGTTAAGTAAGCTCCCTGCGTTTGCTCGAGTGGTTTCTGCAGGCAATCTCTTAAGCCACGTTGGCCACACCATCCTGGGAATGAACACAGTGCAGCTGTACATGAAGGTACCTGGCAGCAGAACGCCAGgccaccaagaaaacaacaacttctGCTCTGTTAACATCAACATCGGACCAGGGGATTGCGAATGGTTTGCCGTACCAGAGCCTTACTGGGGTGTCATGAATGAGTTCTGTGAAAAgaataatatCAACTACTTAATGGGCTCCTGGTGGCCAAATCTAGAAGACCTTTATGAAGCCAACGTCCCTGTGTATCGGTTTATTCAGCGACCCGGAGACCTGGTGTGGATTAATGCTGGCACTGTCCACTGGGTTCAGGCTATCGGCTGGTGCAATAACATTGCTTGGAATATAGGACCACTAACAGCATACCAGTACAAACTGGCTGTGGAGCGATTTGAGTGGAATAAACTGCAGAGTGTTAAGTCCATCGTTCCCATGATCCACCTCTCGTGGAACATGGCACGGAACATTAAGGTGTCTGATCCCAGACTCTTCGAAATGATAAAGTACTGCTTGTTAAGGACGTTGAAGCAGTGTCAGATGCTGAAGGAGGCTCTCCTTGCTGCAGGGAAAGAGATCGTATGGCACGGGAGGACGAAGGAAGAGCCTGCTCACTACTGTAGCATCTGTGAGGTGGAGGTCTTCGATCTGCTCTTCGTCACCAGCGAAAGCAATTCACGGAAGACCTATGTTGTACATTGCCAGGACTGTGCTCGAAAGGGCAGTGCAAACCTGGAAAACTTTGTGGTGCTAGAACAGTACAAAATGGAGGACCTGATGCAAGTCTATGACCTGTTCACATTAGCTCCTCCATTGCCTTCATCCTCATCTTGACATTAACATTGTTCTGTCTGTggacaatatatgtatatattgtctgggtacaatacatatatatattatacacacataaaaagtgaaacatttctgaTATTCAGGAAGTGACCCAGTTCTGCACCACTGGTTTCTGTAGCTATCCCATAAGGCTGCTGGCTGAAAGCTGTGTGTCTATGCAACCTTCCAAGTGCGGAGTGTCAACGGACTGGACGGGAGAGGGTGCTGCTCCTTTTCCAGGACTATTTATAGCTGTTTCAGCTGTActtatataaagaaacaaaaaaggacaaaaaaaaatattgatgaaaaaaaactttttgtatatataaatatcgtGTCACAACTGGCAACATCACACAAAGACTACTGACTTGACAACtttctcttttgtattttgtttctgggCTGATTCATTACCTTTTTTTCATTGAAGTTTTCCCTTATAATGAGTACTAGCTTAGCTGGTCTTTTGTATGGTAGATAGAAATTTTAAGTCTCTTTGGGcaacaaaatctaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

Function


symbol description
kdm6a Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin DNA binding activity; and histone demethylase activity (H3-K27 specific). Acts upstream of or within several processes, including embryonic morphogenesis; face development; and germ cell migration. Predicted to be part of MLL3/4 complex. Is expressed in several structures, including blood island; ethmoid cartilage; otic vesicle; pharyngeal arch; and pronephric duct. Used to study Kabuki syndrome. Human ortholog(s) of this gene implicated in Kabuki syndrome; acute lymphoblastic leukemia; and esophagus squamous cell carcinoma. Orthologous to several human genes including KDM6A (lysine demethylase 6A).

NR:

description
lysine-specific demethylase 6A isoform X4

GO: NA

KEGG:

id description
K11447 UTX, KDM6A; lysine-specific demethylase 6A

RNA


RNA id representative length rna type GC content exon number start site end site
AMCG00014707 True 4165 mRNA 0.47 25 27717966 27762413

Neighbor


gene id symbol gene type direction distance location
AMCG00014702 ccdc80,LOC107695464,LOC107756780,LOC107673676,LOC107748150 coding downstream 208824 27492028 ~ 27509142 (-)
AMCG00014697 atg3,LOC107752093,LOC107659953 coding downstream 235286 27470289 ~ 27482680 (-)
AMCG00014696 NA coding downstream 251112 27441353 ~ 27466854 (-)
AMCG00014694 NA coding downstream 277037 27431251 ~ 27440929 (-)
AMCG00014695 myh9,LOC103376082,LOC106601336,LOC100380669 coding downstream 296297 27420051 ~ 27421669 (-)
AMCG00014712 NA coding upstream 299215 28061628 ~ 28204961 (-)
AMCG00014713 NA coding upstream 456979 28219392 ~ 28220486 (-)
AMCG00014715 ddx3x,LOC108412429,LOC102776245,LOC107564811 coding upstream 526942 28289355 ~ 28315398 (-)
AMCG00014716 usp9x,LOC108272755,LOC107595873 coding upstream 578738 28341151 ~ 28380053 (-)
AMCG00014717 NA coding upstream 725216 28487629 ~ 28490563 (-)
G72089 NA non-coding downstream 187323 27530296 ~ 27530643 (-)
G72049 NA non-coding downstream 298921 27418816 ~ 27419045 (-)
G71961 NA non-coding downstream 785329 26932268 ~ 26932637 (-)
G71882 NA non-coding downstream 1382966 26334655 ~ 26335000 (-)
G71880 NA non-coding downstream 1393712 26324038 ~ 26324254 (-)
G72139 NA non-coding upstream 73926 27836339 ~ 27837927 (-)
G72146 NA non-coding upstream 94326 27856739 ~ 27861375 (-)
G72280 NA non-coding upstream 815996 28578409 ~ 28578734 (-)
G72305 LOC100136012 non-coding upstream 884082 28646495 ~ 28646811 (-)
G72306 NA non-coding upstream 893153 28655566 ~ 28655765 (-)
AMCG00014692 LOC107756725 other downstream 348439 27335695 ~ 27369527 (-)
AMCG00014693 NA other downstream 413369 27285420 ~ 27304597 (-)
AMCG00014630 LOC107672672 other downstream 5473051 22225924 ~ 22244915 (-)
AMCG00014603 tpt1,LOC106582181 other downstream 8492736 19217722 ~ 19225230 (-)
AMCG00014604 kctd4,LOC107688678,LOC107748885 other downstream 8514399 19201803 ~ 19203567 (-)
G72236 rpl8,LOC107595836,LOC107748161 other upstream 567326 28329739 ~ 28332482 (-)
G72477 LOC106598269,LOC101158751,LOC106586690,LOC103361283 other upstream 1626877 29389290 ~ 29398305 (-)
AMCG00014775 NA other upstream 3079110 30841523 ~ 30846800 (-)
G73047 NA other upstream 4500754 32263167 ~ 32263427 (-)
AMCG00014816 NA other upstream 4692893 32455306 ~ 32555945 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000009_02918681_02973307 KDM6A coding CI01000009 null 2918681 ~ 2973952 (+)