raf1b (raf1,raf1b,LOC107742031,LOC107675968,LOC107571214)


Basic Information

Item Value
gene id raf1b
gene name raf1,raf1b,LOC107742031,LOC107675968,LOC107571214
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056709.1
NCBI id CM032078.1
chromosome length 24513629
location 1054577 ~ 1070499 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043252076.1
ACGCTTCGAACCAGTCGACCGTCCacgaaaaaaacaaactagCGTTTTTAGCTTAGTTAGTCGCGCGGCTAGCGGTGACGTCACGGTGACGTCACGCTCTCCCTCGTAGCGATAATCATGGCGGATCAACAATTCAACAACTTTCTCTGATCACTGAAGTCTGCCGCTGCCCGCCGTGATGGAGCACATTCAAGGGGCCTGGAAGAACATCAGTCATGGGTTTGGGTGCAAAGACTCAGTGTTTGAAGATTCCTGCATGTCTCCCACCATCCTCAAGAACTTCCCGTACCGGAGGTTGTCCGATGACGGGCGAATCCCAGACTCGAAAACGAGCAGCACAATCCGTGTCTACCTGCCCAACAAACAGCGGACTGTGGTGAATGTGCGACCGGGTATGACGCTGCACAGCTGCCTCATCAAAGCCCTGAAAGTCCGTGGCCTTCAGCCTGAATGCTGCGCGGTCTTCAAGCTTCATCGAGAACATTCGTTTAAAAAGCTGCGTATGGATTGGAGCACTGATTCTACCTCGCTGGTCGGAGAGGAGTTGCTGGTTGAAGTCTTGGATCACGTACCCCTGACTACGCACAACTTCGTACGGAAAACCTTTTTGAAGCTGGCCTTTTGTGACATCTGTCAGAAGTTTCTCCTGCACGGCTTCAGATGTCAGACGTGCGGCTACAAATTTCACGAGCACTGCAGCACCAAAGTGCCCACGATGTGCGTGGACTGGAGCAACATCCGGCAGCTTCTGCTGTTCCCCACTCCCGGAGAGAACGGGACCCCGGCGCTCCCTCCCCTCTCGTCCCGTCGCATGCAGAACTCTAAATTCTCCTTCAGCCCCTATCACAGATACTCCACGCCGAACGCTTTAAACTACATCACCCCCATGCCGTCCTCCGGCGTCTCTCTCAGTCATAAAGTGCTGTCCACCTCCACCCCAAACGTCCACATGGTGAGCACCACCCAGCCGGTCGACGAGGCTGCTTATCAGGAAGCTTTAGGGCGAGATGAATCAGGAAGCCCGACGGAGTGGTCCAAAACCCCGGCTCCGGCACACAGGGAGAAAGCGCCTGCGACGAACACTCAGGAAAAACGCATCCGTCCCAGAGAGAAGAGAGATTCCAGCTATTACTGGGAGATCGAGGCCACTGAGGTGGTTCTGCTCTCCAGGATCGGCTCAGGGTCTTTCGGCACAGTTTACAAAGGGAAGTGGCATGGTGATGTTGCTGTGAAGATTTTAAAGGTCACAAATCCCACACCAGAGCAGTTACAGGCCTTTCGCAATGAAGTAGCTGTTCTCAGGAAGACCAGGCACgtcaatattgttttgtttatgggATACATGACCAAGGCAAACTTGGCCATTGTGACGCAGTGGTGTGAAGGAAGCAGTCTCTACAAACATCTGCACGTGCAGGAGACCAACTTCCAGATGTTCCAGCTGATGGACATCGCCAGACAGACGGCGCAGGGCATGGATTACCTGCATGCAAAGAATATCATCCATCGAGACATGAAGTCAAACAATATCTTCCTACATGAAGGGCTGACGGTGAAGATCGGTGATTTTGGTCTGGCCACGGTCAAGGCGCGGTGGAGCGGCCCGCATCGAGTGGAGCAGCCGTCTGGATCCATTCTGTGGATGGCTCCCGAGGTCATCCGGATGCAGGACAACAATCCTTACAGTTTTCAGTCGGATGTGTACTCGTACGGTATCGTCCTGTATGAGCTGATGACGGGAGAACTGCCTTATTCTATGACTGGAAACAGAGATCAGATCATCTTCATGGTGGGGAGAGGCTATCTGACCCCTGACCTCAGCAAACTCTACAAGAGCTGTCCCAAAGCCATGAAGAGGCTCGTCGCCGACTGCATCCAGAAGTCCAAAGACGACCGGCCGCTGTTTCCCCAGATCCTGTCCTCGATCGAGCTGCTCCAGCACTCGCTCCCTAAAATAAACCGCAGCGCGTCGGAGCCGTCGCTCCACAGAGCCTCGCACACCGAGGACATCAACGTCTGCACGCTGGCGCTCTCCTCCGCCTTCAAGTGACGCCGTGTTCCTGCGCTCCGTCTAGTGTACTCCGTGTTAGGTCTTTGGTTCACCCGCTCGAGCTGGACCTCTCTTCAGTGCCGAGGGAACGCTAACAGCACTTTCTTCCTCTTTGATCTGTACCGAGCGGGACCGCTCCGAGCTCCGCCGGCTTTCGTCACCCGTACAATCACGTGCCTGGAAGCCGAGGCCCCGGCTGTATACTCCCTAAGTGCCAGTGCCGCTCGTGGCTTTATCGAAACGCCTCCTAGCACAAGGTGTAGGGAGCACTTTACCATCTTGTGTCTTGCTGTCTCTTTGACTGTGTGTATGTTACAGAAATCCAAGAAGGAAGAGTGGGTATTAACTTTATCACGAGACTTACTAGGGATCcgttttttttggcttttagtGGAAGATTAACTTGTAAACTTGACAGATTGTTTattcattgtattttaataaaattaagttaaatgcACCACACAAGCTCGGTTTTTAAGATGAGAAGATTATGGCTTCTTGTCAAGCGCAGACGGCGCTTCGAGGTTAGCGGGACGGAACCGATTTCTACGGACTcgacggatgctctgcagccaatgggtgccgtcagaacgagatgaaaacatcacaataatccacagcactccggtccatcggtgaacatctggagaagaaaaACGCTGAGACAAACCAAGACGTCTTTcacttcaaactgttgcttacaaaatatccataataaaatgcatagtCCGTAATACTGCTAttcttttaagaaaaatctgatgttggtctgaataaatgctgaaattaa
>XM_043252077.1
CGGCACTTCTTGATTCAGATCACTGAAGTCTGCCGCTGCCCGCCGTGATGGAGCACATTCAAGGGGCCTGGAAGAACATCAGTCATGGGTTTGGGTGCAAAGACTCAGTGTTTGAAGATTCCTGCATGTCTCCCACCATCCTCAAGAACTTCCCGTACCGGAGGTTGTCCGATGACGGGCGAATCCCAGACTCGAAAACGAGCAGCACAATCCGTGTCTACCTGCCCAACAAACAGCGGACTGTGGTGAATGTGCGACCGGGTATGACGCTGCACAGCTGCCTCATCAAAGCCCTGAAAGTCCGTGGCCTTCAGCCTGAATGCTGCGCGGTCTTCAAGCTTCATCGAGAACATTCGTTTAAAAAGCTGCGTATGGATTGGAGCACTGATTCTACCTCGCTGGTCGGAGAGGAGTTGCTGGTTGAAGTCTTGGATCACGTACCCCTGACTACGCACAACTTCGTACGGAAAACCTTTTTGAAGCTGGCCTTTTGTGACATCTGTCAGAAGTTTCTCCTGCACGGCTTCAGATGTCAGACGTGCGGCTACAAATTTCACGAGCACTGCAGCACCAAAGTGCCCACGATGTGCGTGGACTGGAGCAACATCCGGCAGCTTCTGCTGTTCCCCACTCCCGGAGAGAACGGGACCCCGGCGCTCCCTCCCCTCTCGTCCCGTCGCATGCAGAACTCTAAATTCTCCTTCAGCCCCTATCACAGATACTCCACGCCGAACGCTTTAAACTACATCACCCCCATGCCGTCCTCCGGCGTCTCTCTCAGTCATAAAGTGCTGTCCACCTCCACCCCAAACGTCCACATGGTGAGCACCACCCAGCCGGTCGACGAGGCTGCTTATCAGGAAGCTTTAGGGCGAGATGAATCAGGAAGCCCGACGGAGTGGTCCAAAACCCCGGCTCCGGCACACAGGGAGAAAGCGCCTGCGACGAACACTCAGGAAAAACGCATCCGTCCCAGAGAGAAGAGAGATTCCAGCTATTACTGGGAGATCGAGGCCACTGAGGTGGTTCTGCTCTCCAGGATCGGCTCAGGGTCTTTCGGCACAGTTTACAAAGGGAAGTGGCATGGTGATGTTGCTGTGAAGATTTTAAAGGTCACAAATCCCACACCAGAGCAGTTACAGGCCTTTCGCAATGAAGTAGCTGTTCTCAGGAAGACCAGGCACgtcaatattgttttgtttatgggATACATGACCAAGGCAAACTTGGCCATTGTGACGCAGTGGTGTGAAGGAAGCAGTCTCTACAAACATCTGCACGTGCAGGAGACCAACTTCCAGATGTTCCAGCTGATGGACATCGCCAGACAGACGGCGCAGGGCATGGATTACCTGCATGCAAAGAATATCATCCATCGAGACATGAAGTCAAACAATATCTTCCTACATGAAGGGCTGACGGTGAAGATCGGTGATTTTGGTCTGGCCACGGTCAAGGCGCGGTGGAGCGGCCCGCATCGAGTGGAGCAGCCGTCTGGATCCATTCTGTGGATGGCTCCCGAGGTCATCCGGATGCAGGACAACAATCCTTACAGTTTTCAGTCGGATGTGTACTCGTACGGTATCGTCCTGTATGAGCTGATGACGGGAGAACTGCCTTATTCTATGACTGGAAACAGAGATCAGATCATCTTCATGGTGGGGAGAGGCTATCTGACCCCTGACCTCAGCAAACTCTACAAGAGCTGTCCCAAAGCCATGAAGAGGCTCGTCGCCGACTGCATCCAGAAGTCCAAAGACGACCGGCCGCTGTTTCCCCAGATCCTGTCCTCGATCGAGCTGCTCCAGCACTCGCTCCCTAAAATAAACCGCAGCGCGTCGGAGCCGTCGCTCCACAGAGCCTCGCACACCGAGGACATCAACGTCTGCACGCTGGCGCTCTCCTCCGCCTTCAAGTGACGCCGTGTTCCTGCGCTCCGTCTAGTGTACTCCGTGTTAGGTCTTTGGTTCACCCGCTCGAGCTGGACCTCTCTTCAGTGCCGAGGGAACGCTAACAGCACTTTCTTCCTCTTTGATCTGTACCGAGCGGGACCGCTCCGAGCTCCGCCGGCTTTCGTCACCCGTACAATCACGTGCCTGGAAGCCGAGGCCCCGGCTGTATACTCCCTAAGTGCCAGTGCCGCTCGTGGCTTTATCGAAACGCCTCCTAGCACAAGGTGTAGGGAGCACTTTACCATCTTGTGTCTTGCTGTCTCTTTGACTGTGTGTATGTTACAGAAATCCAAGAAGGAAGAGTGGGTATTAACTTTATCACGAGACTTACTAGGGATCcgttttttttggcttttagtGGAAGATTAACTTGTAAACTTGACAGATTGTTTattcattgtattttaataaaattaagttaaatgcACCACACAAGCTCGGTTTTTAAGATGAGAAGATTATGGCTTCTTGTCAAGCGCAGACGGCGCTTCGAGGTTAGCGGGACGGAACCGATTTCTACGGACTcgacggatgctctgcagccaatgggtgccgtcagaacgagatgaaaacatcacaataatccacagcactccggtccatcggtgaacatctggagaagaaaaACGCTGAGACAAACCAAGACGTCTTTcacttcaaactgttgcttacaaaatatccataataaaatgcatagtCCGTAATACTGCTAttcttttaagaaaaatctgatgttggtctgaataaatgctgaaattaa

Function

symbol description
raf1b Predicted to enable protein kinase activity. Predicted to act upstream of or within intracellular signal transduction and protein phosphorylation. Predicted to be active in cytosol; mitochondrion; and plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 2; adenocarcinoma (multiple); and dilated cardiomyopathy 1NN. Orthologous to human RAF1 (Raf-1 proto-oncogene, serine/threonine kinase).
raf1 Enables enzyme binding activity; identical protein binding activity; and protein serine/threonine kinase activity. Involved in several processes, including activation of adenylate cyclase activity; positive regulation of MAPK cascade; and positive regulation of peptidyl-serine phosphorylation. Located in Golgi apparatus; cytosol; and nuclear speck. Colocalizes with plasma membrane. Implicated in Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 2; adenocarcinoma (multiple); and dilated cardiomyopathy 1NN. Biomarker of colorectal adenocarcinoma; colorectal adenoma; and prostate cancer.

NR:

description
PREDICTED: RAF proto-oncogene serine/threonine-protein kinase

GO:

id name namespace
GO:0035556 intracellular signal transduction biological_process
GO:0006468 protein phosphorylation biological_process
GO:0005057 obsolete signal transducer activity, downstream of receptor molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043252076.1 True 2843 mRNA 0.52 17 1054577 1067056
XM_043252077.1 False 2712 mRNA 0.52 17 1054577 1070499

Neighbor

gene id symbol gene type direction distance location
mkrn2os.1 NA coding downstream 8621 1044079 ~ 1045956 (-)
mkrn2os.2 LOC107758069,LOC107687314,LOC107564281 coding downstream 11158 1040367 ~ 1043419 (-)
LOC122353725 timp4,LOC107571219,LOC107667868,LOC107564284,LOC107687318,LOC107742036 coding downstream 64315 985343 ~ 990262 (-)
LOC122353727 NA coding downstream 74461 977597 ~ 980116 (-)
tamm41 tamm41 coding downstream 115305 933852 ~ 939272 (-)
rab43 rab43,LOC107758163,LOC107700634,LOC107675972,LOC107742026 coding upstream 22773 1093272 ~ 1097710 (-)
trnac-gca_5 NA coding upstream 35846 1106345 ~ 1106416 (-)
trnac-gca_6 NA coding upstream 36280 1106779 ~ 1106850 (-)
trnac-gca_7 NA coding upstream 36490 1106989 ~ 1107060 (-)
trnac-gca_8 NA coding upstream 36706 1107205 ~ 1107276 (-)
G78331 NA non-coding downstream 2033 1050078 ~ 1052544 (-)
G78327 mkrn2,LOC107675967,LOC107571211,LOC107571213,LOC107742032 non-coding downstream 4641 1049406 ~ 1049936 (-)
G78324 pparg non-coding downstream 30767 1021476 ~ 1023810 (-)
G78298 NA non-coding downstream 147003 905807 ~ 907574 (-)
G78226 slc6a11,LOC107746711,LOC107686974,LOC107561801,LOC107697565,LOC107750026 non-coding downstream 331013 722464 ~ 723564 (-)
G78338 NA non-coding upstream 2047 1072546 ~ 1074456 (-)
G78339 cnbp,cnbpb,LOC107742030,LOC107742027,LOC107675970,LOC106583855 non-coding upstream 5286 1075785 ~ 1158877 (-)
G78354 NA non-coding upstream 97823 1168322 ~ 1168814 (-)
G78373 NA non-coding upstream 133377 1203876 ~ 1204107 (-)
G78378 LOC107730614,LOC107551316,LOC107654797,LOC107722003 non-coding upstream 141777 1212276 ~ 1213265 (-)
LOC122353728 NA other downstream 79790 972954 ~ 974787 (-)
G78195 atp2b2,slc6a1b,slc6a1,LOC107561799,LOC107570616,LOC107670967,LOC107746710,LOC107570615,LOC107697564 other downstream 260441 599107 ~ 794136 (-)
G78170 NA other downstream 598579 453134 ~ 455998 (-)
G78144 alas1 other downstream 605676 443885 ~ 448901 (-)
LOC122353669 mettl21b,LOC107684011 other downstream 649166 402940 ~ 405411 (-)
phactr3b phactr3b,LOC107730624,LOC107670936,LOC107722000,LOC107654794,LOC107550338,LOC103365918,LOC106955159,LOC104947949 other upstream 146720 1217219 ~ 1260090 (-)
LOC122354408 LOC107683642,LOC107737350,LOC107572058 other upstream 518205 1588704 ~ 1696787 (-)
nab2 nab2,LOC107557549,LOC107730902,LOC107696037,LOC107683651,LOC107737369 other upstream 634125 1704624 ~ 1716129 (-)
LOC122354491 gata2a,gata2,LOC107680419,LOC107744843,LOC107573143 other upstream 1742853 2813352 ~ 2816128 (-)
LOC122354336 srpk2,srpk1b,LOC108428417,LOC107714507,LOC107699336 other upstream 1749089 2819588 ~ 2830203 (-)

Expression


Co-expression Network