cldn5 (cldn5)


Basic Information

Item Value
gene id cldn5
gene name cldn5
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035902.1
NCBI id CM008305.1
chromosome length 52532229
location 27071878 ~ 27074018 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007247196.3
gctgaaagtTTTGCTTTGGACTCGgacccctcctcctccttctctccttcaGGCAAGCCTGCCTCCGCTATTCCTGTGATTTTATTATTCTCCTCCACTGGCTTTTCCAGAGCAGTGCGAGGAAAGTCCGTTAGTCTGCAGGATACTCGGAGCGGGGTGATGAGCTGTAGTACCTGAGCACCACTGaaacaacttatttttttttttcatccagaAACATTTTTTAACGCCTTTTTCAAACTCTTCAGAGCAGACCCAGAGCTTCTTCTTCCTGCCCTCTGAACGCaggtatattattatatatttttaagtgaaattaGGCAGAGGAGGAAAATGGCCTCGGCCGGTCTGGAGATCCTGGGGCTGACGCTGTGCATGCTGGGCACGCTGCTGGAGATGGTGGGCTGCGGCCTGCCCATGTGGAAGGTGACGGCGTTCATCGACGCCAACATCGTGGTGGCGCAGACCATCTGGGACGGCCTGTGGATGTCGTGCGCCGTGCAGAGCACGGGCCAGATGCAGTGCAAGGTGCACGACTCGATGCTGGCGCTCGCCCCTGACCTGCAGGCGGCGCGCGCGCTCACCGTGGTCTCGTGCGTGCTCGCCGTGTTCGGGCTGATGGTGGTGGTCGCGGGCGCGCAGTGCACCAACTGCATCCGCGACGAGCGCCTGAAGGCGCGCGTGGTGGCCGCCGGCGGCGTGCTGTACATCGCCAGCGGCGCGCTGCTGCTCGTGCCCCTCTGCTGGATGGCCAGCAGCATCATCGCGGACTTCTACAACCCGCAGGTGCACGCGGCCAAGAAGCGCGAGATCGGCGCCTCGCTCTACATCGGCTGGGCGGCCAcggggctgctgctgcttggcGGAGCCACGCTCTGCTGCTCGTGTCCCTCCAGCCCCAGCGGATACTCCGTCAACTACGTGCCCACCAAGCGCCCGGCCACGACTAACGGCGACTACGACAAGCGGAATTACGTCTAGGCTctcctgttttatttctttaattcaccggcacctgtacacctgttcttcttctttaacttgagaaatgacaaaaacaaaaagaaaaaacttaaatgtaaatgacttttaatgacttttttttattgtgtttaaagaCGCTGCATAGACATTTGCTACTACTGAGAGATAAGCCCAAACGGGCTGCGGACCCCATGGACACTGTTTTTACCTGTTTGTACTCTCGgacattgttttgtttgtgttttgttttgtttcatgcCTTTTGGAAGGAGGACCTGAAAGAGGTCaatttagttagctaggtaCCTTCACAGCAAAATCCCCAGTGTTGAatgaaaattatgaatttcAGCGACGAGTAAAAAACTATGAATTAGCTGCTTACAGTGTCTAGACTGATCATCCAGCTATATTTGGGGTAGTGAGAaaaaatagtgaactatattctTTCttaaatcaaaaatatatactgcAGTAGCTGCATAGATAAAGAAACACAATTGTGTGGGTCTTTTGAACACTAACTAGCCAGCTTAATGCCGTAGATGCACCATTTGCAGACAAGTgccacaaaataccaaaatgATTCTGTAAATGTTCATTCAATACTATAATGTGCTGTGATGAACAAAAGTATGTTTTGTTACTCGAACTGCCATCAAGTCAACATATTAATTCTCATTCAACCATGGGGGTTTTGCTATGTTGCATTCAGTTTAGGCCAAAATCACGTATGTAGATTTAAGCTTTGGCTCTTTTGACCAGAGTTGTTTACCGGtatcaaaatgttttattattatcaaaatAATTGTATGGGGCAGTTGACACTGTCTTTTTCTTACACATTATGCCATCATGGACACAGCTGGATAAGACAGCAACTCCTGACTGCTCTAAACAAAGCCGTATCCACAACGAGGTGCTCAGTAAGGTGGAAAGTGCTCTTCAGTGTGGAATTAACTTCGCTGGACATCTGTTACCGGTGCCTTGTAATGATGGGacttattgttttgttttgcccttttaATAAGACTATCAGTGCCAAAAGCTGTCTGCAGTCGTTTGGCagaaatgattatttttgtaaCTTCCAAAAATGGCCTTCTGTGTTACATGTTGTTTTGAATACTGTTttgaataaacatttattacgATAA

Function

symbol description
cldn5 Predicted to enable identical protein binding activity. Involved in several processes, including establishment of blood-retinal barrier; positive regulation of bicellular tight junction assembly; and regulation of gene expression. Located in apicolateral plasma membrane and bicellular tight junction. Colocalizes with cortical actin cytoskeleton. Implicated in schizophrenia.

NR:

description
claudin-5

GO:

id name namespace
GO:0005886 plasma membrane cellular_component
GO:0005923 bicellular tight junction cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005198 structural molecule activity molecular_function

KEGG:

id description
K06087 CLDN; claudin

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007247196.3 True 2141 mRNA 0.47 1 27071878 27074018

Neighbor

gene id symbol gene type direction distance location
ufd1 ufd1l coding downstream 22816 27041506 ~ 27049062 (-)
tmem127 tmem127,LOC107552193,LOC107713035,LOC106579884,LOC106585551 coding downstream 36904 27029916 ~ 27034974 (-)
LOC103022143 NA coding downstream 43384 27024622 ~ 27028494 (-)
LOC103022658 es1,LOC108430344,LOC105894898,LOC107553036,LOC107671040 coding downstream 48610 27019132 ~ 27023268 (-)
LOC103024013 adra1aa,LOC108430341,LOC107553034,LOC107699645,LOC107671010,LOC107713032,LOC108264882,LOC105894890 coding downstream 151460 26884643 ~ 26920418 (-)
srrd NA coding upstream 133290 27207308 ~ 27211033 (-)
LOC103044306 pptc7a,LOC103044306,LOC108430358,LOC107552188,LOC107553043,LOC107699657,LOC107671007,LOC105891618 coding upstream 148822 27222840 ~ 27236161 (-)
LOC103044021 LOC103044021,LOC108430310,LOC103358995,LOC101071916,LOC104927948,LOC103366907 coding upstream 166972 27240990 ~ 27259800 (-)
LOC103030651 cit coding upstream 433685 27507703 ~ 27588964 (-)
LOC103030338 LOC108413054 coding upstream 530853 27604871 ~ 27659305 (-)
G54716 NA non-coding downstream 11427 27058737 ~ 27060451 (-)
G54702 NA non-coding downstream 97786 26973568 ~ 26974092 (-)
G54699 tmem230,ct030,LOC103023473,LOC106579885,LOC107713020,LOC101077900,LOC105894893,LOC107553029 non-coding downstream 98885 26962935 ~ 26972993 (-)
G54656 LOC108430339,LOC108265827,LOC107699644,LOC107560275,LOC107552154,LOC107714550 non-coding downstream 261210 26804601 ~ 26810668 (-)
G54651 NA non-coding downstream 322599 26749076 ~ 26749279 (-)
G54846 NA non-coding upstream 73397 27147415 ~ 27505872 (-)
G54869 NA non-coding upstream 169062 27243080 ~ 27245098 (-)
LOC111192649 NA non-coding upstream 337216 27411234 ~ 27412937 (-)
LOC111192650 NA non-coding upstream 588308 27662326 ~ 27663868 (-)
G54916 NA non-coding upstream 638454 27712472 ~ 27714921 (-)
LOC103024953 rnf165b,rnf165,LOC108430336,LOC108265796,LOC107726876,LOC107569673,LOC107712483 other downstream 292164 26761132 ~ 26779714 (-)
ccl28 NA other downstream 495453 26573400 ~ 26576425 (-)
LOC103042298 slc35d2 other downstream 501939 26558406 ~ 26569939 (-)
fam240a LOC108441996 other downstream 1509739 25549350 ~ 25562139 (-)
jcad NA other downstream 2073758 24950612 ~ 24998120 (-)
G54854 dhx37 other upstream 92668 27166686 ~ 27168510 (-)
G54873 NA other upstream 395200 27469218 ~ 27473347 (-)
G54947 NA other upstream 654693 27728711 ~ 27731079 (-)
LOC103039900 NA other upstream 952721 28026739 ~ 28043251 (-)
G55023 cunh5orf51,clg13h5orf51,LOC103038767,LOC107667559,LOC107686395,LOC106585203 other upstream 1079403 28153421 ~ 28157449 (-)

Expression


Co-expression Network