zeb1 (zeb1)


Basic Information

Item Value
gene id zeb1
gene name zeb1
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035902.1
NCBI id CM008305.1
chromosome length 52532229
location 24494315 ~ 24607305 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022670368.1
GGCAgcgtttacacacacacacgcgcacacacacactcagcgaAAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCACGAGCGTGAGTAACTACAGCCATGTACTGGAAGGACAGTCAGACTCAGACGATGAGGATAAGCTTCACATCGTGGAGGAGGAGGGAAGCCCCCTGGATGGAGCTGATGGAGACAGTGTCGCCCACGATGACGAGCCCAACGGCCCAGAGGACAGATGGGATGAAGTGAAAGACGAGTGTGTGTCAGAAGAGGATGAGAGGAGTCGAGATGCTCTGGTTGAGAAGATCCTTCAACAAGGAGACACAGCGGTCATTTTTCCAGAAGCACCAGAAGACGAACCGCGACAGGGCACACCAGAGACCAGCGGCCACGACGAGAACGgcaCCCCAGATGCTTTCTCGCAGCTCCTCACATGTCCGTACTGCTCTCGCGGCTACAAGCGCTACACCTCCCTGAAGGAGCACATCAAGTACAGGCACGAGAAGAGCGAGGACAACTTCAGCTGCTCCCTCTGCAGCTACACCTTCGCCTACCGCACACAGCTCGACCGACACATGAGCGCACACAAAACAGACCGAGACCAGCGGCATGTAAACCAAACAGGGGGTGGAGGAAATCGTAAGTTTAAGTGCACTGAATGTGACAAAGCCTTCAAATACAAACACCACCTGAAAGAACACCTGCGAATCCATAGCGGAGAGAAGCCATACGAGTGCTCGAACTGTAAGAAGCGTTTCTCCCATTCCGGCTCCTACAGCTCCCACATCAGCAGCAAGAAATGCATCGGCCTCATCTCCGTCAACGGCCGGCCGCGGCCTTCTCCGGCCACAGGAGGCGCCAAAACCCCTCAGTGCCCTTCCCCATCCCTGCCCTCATCTCCTGCCACCGCCCGTACCCAGCTCAGAGACAAACTGGAGCACGCTAAGCCCCTGCAGGAGCAGCTCCCGCTCACACAGATCAAGTCTGAGCCCATGGACTATGAGTACAAGCCTGTGGTTGTGGCCCCGGCTGCTGGGGGCGTGAACGGAGTTTTCCAGGGCGGAGCTGCGGCCCCCCTTCAGGGAGCAGTACAAGCTGTGGTTCTGCCTACTGTGGGCCTGGTCTCACCTATCAGCATCAACCTGGGTGACCTGCAGAACATGCTGAAGGTGGCAGTGGACGGGAACGTGATCAGGCAGGTGCTGGAGAACGCCCAGACCAAAGGCCAGCCTGCAGGAACTGGGAGAGTGGCAATCGCCCAGGCTCCTCAGCAAGTTATCCAAGCCATTAGTCTTCCTATTGTAGACCAGGATGGAACGGCCAAAATCATCATCAACTACAGCTTGGATCCATCGCAGGCCCAGGCAGCCCTGCAGAACTTGAAGAAAGAGCCTATTGGTCAGAACACTGACGCCTGCAAGACAGAGAGACTGCCAGAGGACCTGACCATCAAAAGCAAGACAAGCAAAGAGAAGCCTACTATTACTACGGGTGAAGAGAAGCAGCTGGAGAAGTCTGTCAGTGATGTATCACCCAAACACTGTGGCAAGGAAGGACAGCAGATCAACGGGATGCACCCGGAGGAGAAGTCTGAAGTAGATATTGGACTATGTCCTGGGAAGCCTCCACTGAAGAACCTTCTGTCCCTACTCAAGGCTTACTTTGCATTAAATGCTGAGCCCACCAAGGAGGAACTGGCCAAAATCTCTGAATCAGTCAGCCTTCCTACCGAAGTGGTCAGAAAGTGGTTTGAGAAGATGCAATCCGGTCAGATTTCTGTGGAAATGTCTTCTCCATTGTCGCAGAATGAGCAGAATGCTGGTGAAGATACTGATGAAACACCAGAAGAGCTCATCAAGTTGACACTTGAGAACGACAAAGAACCCCAGAAGAACCTAGAAGAGCAGGAGATGGAACTGCATAGCCCTGCAGAGGGCGCTACAGCTGGGATAAATGGGACAGAAAATGGCCCAGCATCCCCTTCACCACTGAACCTGTCTGCAGACGGGCCCGTCCCAGCCCGGACTGCAGAGGAGGGTGATGGACCCCTCGATTTGTCCCTCCCCAAATCCGCCGCTGCACCTAATGCGGCTACCACTCACGCTAACACTGTTTACTCGGCTCAGGACGAGCCACTGAACTTGACTTGCACAAAGAAGGAAGCGTCCGGCATCGCAAACGCTAGCGCTGCCGGCTATGCTAACCAAACAAGTGCCAATCCCATAAACATTGTGACCACTCAGCTGCCCACACTGGTGGCCATCACCGATCAGGGCCACGGGCAGTGCCTACGCGCCCTCACCACCACTAAACAGACCATCCTGATTCCACAGCTGGCCTACACCTATACCACTACAGCCTCCAGCCCAGCAGGGGGCGACACACAGCAGAAGACCATACTGCGGGTCAACGGAATCAAGGAGGAAAAGCTGGAGAACACCTCAGAACTGGCTTCAGTTTTAGATGAGCAGACAGACTCAGACTCCGGCCCAGCgaggaagaagatgaagaagactGAGAACGGCCTGTACGCCTGCGACCTGTGTGACAAGATCTTCCAGAAGAGCAGCTCGCTGCTTCGACATAAATACGAACACACAGGTAAACGGCCCCACGAATGTGGAATCTGCAGCAAAGCTTTCAAACACAAGCACCATCTGATCGAGCACTTGCGTCTGCACTCAGGAGAAAAGCCATACCAGTGCGATAAGTGCGGCAAACGCTTCTCCCACTCAGGCTCCTACTCGCAGCACATGAACCACCGCTACTCCTACTGCAAGAAAGAGAACCTCGGCCAGGACCTTCTGCAGAGCCCCGAGGAGGAGGAGAACCAGAGCGAGGAGCAGCCTCGACCCGAGAGCACCGCGCCCTCGCCTCCGTCACAACTGGACTCAGACGAGCGAGGGAGCAGCGCCAGGGAGGACGAGGAgagcgaggaggaggaggaggagatgggCTCTGGCAGCATGGTGGACGAGGACGAGATCCAGGTGGTCCAGATCGGAGAggagggaggagaagaggaggatgaggatgaggaggaggagaggatggaggaagaggagatGACCACGACACAGaatggaggagaggaagagacagtggTGGAAACACtagtagaagaagaaggaggaggaggaggagaagaagaagaagaggatggagagatgatGAAGGTTGTGGTGATGCAGGACTgcgaggaagaggaagaggaggaggagcaggacgAACACGACCGAGAAAGAGCAAAAGCAGAGGAACAAGCAGAAAACGCAGAACCAATGGACACGCAGGAGAACAAGGACGAGACACAGGAACAAACTGAGGCTGATGAGGCCGGAGAGAGGAACGAAGGCGATGAACGAGGAGGAGAAGAACTTGTGAAGGTGAACGGTGCAAATGAAGGAAACACACCCAGTAAAAACGAGATgtgaaatgaacagaaaaataaaagaacacagcTGGGCTTTTGTTGCCCTGATCCTTTGCTACATCGTTTTACAGACGTTACTAATTTGAAGGAAACAAAGACTGCAGATGTGTCTCTTTCAGAGAGTTCAGACTGACTGTGCAGTAATGAAGacagaagaaggaggaggaggaggaagaggaggagagagaggaggaggagcgcTGGAGCGCTGACGCTGCATTTTAGCCCACTACTGTGTATAAAACCCCCTGGTGTGCctgattaagaaaaaaaaagaaaaacaaaacaaactagtTGCTTTTCCACAAAACCAGTGTTTATGAATATggtttgtataaatataaagtttaacaaacgtaaaaaaaaaaattgacgcATATACGGACTGAAAGCTAGACACGTTTTagctaataatattttattactaaaacACCTTGGGTCAATTTCTTTTTATCAGTGTTACTAATTTTTTGTCACTCTTGTTTAAACCTTAAGAAGTTGTACAGTTGGGAGAGATTTCTATACGTTTTTATTGCCAATGAACAAAACTcagtattttattgcatttgaaggagaagaaaaaaaaaatcctgtgcACTACCATACTCCCAGTTTACCGATGGATCACCTCTGTGGGCCTTGCGTTGTTTAATGTCTACCTTTCAGTATTAGCACTCTGTTAGAGCTAACCCCTATGCCACGCTAGCCGGCGCTAGCCCCACATTTACCTGtctgatttactttttttgtgtggtaaaGAAGTGGTCTATGAGccttaaatgtaagaaacaagctaacaaaaaaaaaaaaacgatttacaCGGGTTTGATGGGATGGCAGGATGGTGGCAAACCATCCGAAATCATCTGAAAACTAAACGTTTCTGAGAAGCAGTATTATttctgagaaagagaaaaagcaaagtcaaaaatgtcaaaaattcACTCCTCAGTCTGAGACCGCCCACTCTCCGTTATGCAAAAGCATGCATGTTGAAGTGCCATTCGACAGTGCTCTCGCCGTTCCCGGACACTGTTACCAGGCAGCATGTTGACCTGTGAGCTGGCGCTGTCTTTAACgttttattaataatgtggtagcaaacctaaccttaaacctGAACCcctgaacctaaacctaaaccactAGTCCTGACCAAAGGACAAGACTGCCTCTTTTTTCTAAACTCAGTTCATCCCACCTGTCACTGCAGTTCAGGACAAAACAATCAAAAacgagaacaaaaaaaagaaaagtttggtTTCTTTCGTTTCAGCCTTGAAGTGTTTGTTTGATCTTTTTTGTTCCTCTGTTTGTTTGGTGCACTTCTTTATCCCATTGGCTGCACATACACTTTTTCTTCAGGTAACAACCATAAGCAAATATGAACCCGTAATGACCCTCACCTGacattggttttgtttttttatttctacttttaTAACAGTCAGTATTAATTTCTGTCTATtctgtttgtttgattgtttgtttgttggtttgtttgtttgtttttaagtgaacattgtgtattgtttgtttgcagtcaTGGCAGTATTATTCTTCACCCCCTTCACCAGTATAACTTTGTTTAGTTTTAGAGAccttttatatttatgtgtcttatttttgtatttttctttatggTTATTTATTACACGACGTAGTGTACAATATTGTAGTTTgtattaatacaataatatattttagtatgaAGAATAATTTCGAAGATAAATGAATGCAAAGCTGGGGAAGAACCTCTAGCATTTcaaagtgttttaaaacagAAAGAGTATTATTTTCAATTGTTTGAAAgaattaaaaaagtgaaataaaatgtaaaaaaaaaaagaaagaaagaaagaacgaaaGACAGACCACCCAATGAAGTATTGGACCTTTATCTTCTCGCGTTGCCCATTCTCATGTTACTGTGTCTTTCCCCACTAGACCTCGAGGCTACTGAACATTGATAAACTAATTGTATGCTATACACGCATGAGTCTTCGCTGTTGTACTGAAGGATCATCCTTAACCACGATACTGTGCTGCCCTTTTTACGAAAAGCCAAAATGTCGTTAACGTCaacttttgtttgattttgtgcCAATGTGTTCGTTTGTCCACGTCAAGGCCACAACTTGTTTTATATGTCCCTGTTTTAATCTAtggttctgtattttttttatagatagttttttttttttttttttttttttttttttttttttttttttatgactccCCATCtcacaataaaatacatcaaGAATTGAA

Function

symbol description
zeb1 Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of endothelial cell differentiation and negative regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. Implicated in Fuchs' endothelial dystrophy and posterior polymorphous corneal dystrophy 3.

NR:

description
PREDICTED: zinc finger E-box-binding homeobox 1 isoform X1

GO:

id name namespace
GO:2000145 regulation of cell motility biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0007369 gastrulation biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K09299 ZEB1; zinc finger homeobox protein 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022670368.1 True 5728 mRNA 0.48 8 24494315 24607305

Neighbor

gene id symbol gene type direction distance location
LOC103023701 LOC103023701,LOC108429359,LOC107597744,LOC101481087,LOC106560865 coding downstream 2429312 22056973 ~ 22065003 (-)
LOC103023380 sar1aa,sar1b,LOC103023380,LOC108429350,LOC107659671,LOC105903360,LOC103362473 coding downstream 2440227 22046496 ~ 22054088 (-)
anapc16 anapc16,cj104 coding downstream 2555867 21933269 ~ 21938448 (-)
ddit4 ddit4 coding downstream 2572698 21919529 ~ 21921617 (-)
narf narf,LOC107581643 coding downstream 2608874 21873489 ~ 21885441 (-)
mtpap NA coding upstream 464149 25071454 ~ 25099104 (-)
ppic ppic,LOC107704600,LOC107713556,LOC107566397,LOC107726227,LOC100333141 coding upstream 778385 25385690 ~ 25390707 (-)
cep120 cep120,zgc:163014,LOC107712640 coding upstream 843807 25451112 ~ 25471966 (-)
LOC103046226 znf608 coding upstream 866580 25473885 ~ 25483984 (-)
LOC103037139 LOC108442001,LOC108265961,LOC107697601,LOC107712558,LOC105890695 coding upstream 879257 25486562 ~ 25505546 (-)
G54227 NA non-coding downstream 1345 24492701 ~ 24492970 (-)
G54224 NA non-coding downstream 31183 24459779 ~ 24463132 (-)
G54204 kif5b,LOC107568141,LOC107654561,LOC107753262 non-coding downstream 153490 24340011 ~ 24340825 (-)
G54202 NA non-coding downstream 162245 24331608 ~ 24332070 (-)
G54188 NA non-coding downstream 203538 24272991 ~ 24290777 (-)
LOC111192640 NA non-coding upstream 8740 24616045 ~ 24637375 (-)
G54237 NA non-coding upstream 110176 24717481 ~ 24718187 (-)
G54238 NA non-coding upstream 118492 24725797 ~ 24726344 (-)
G54239 NA non-coding upstream 132531 24739836 ~ 24740055 (-)
G54276 NA non-coding upstream 203515 24810820 ~ 24812627 (-)
G54205 kif5b,kif5bb,LOC108430866,LOC107753262 other downstream 142379 24341400 ~ 24351936 (-)
G53996 NA other downstream 1402340 23091306 ~ 23091975 (-)
G53607 fbxo11,fbxo11b,fbxo11a,LOC107749363,LOC107550041,LOC107728720 other downstream 3674906 20817839 ~ 20819409 (-)
G53598 msh2,LOC107728724,LOC107673650,LOC107582784,LOC107550043,LOC107749362,LOC107698830 other downstream 3706697 20783738 ~ 20787618 (-)
G53562 LOC107396020,LOC107670363,LOC105896953,LOC102778633 other downstream 3803893 20621569 ~ 20690422 (-)
svil NA other upstream 178946 24786251 ~ 24920590 (-)
jcad NA other upstream 343307 24950612 ~ 24998120 (-)
fam240a LOC108441996 other upstream 942045 25549350 ~ 25562139 (-)
LOC103042298 slc35d2 other upstream 1951101 26558406 ~ 26569939 (-)
ccl28 NA other upstream 1966095 26573400 ~ 26576425 (-)

Expression


Co-expression Network