XLOC_000088 (en1b)


Basic Information

Item Value
gene id XLOC_000088
gene name en1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 7679328 ~ 7683372 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000174
GAAAGAGTTTGTTAAGCGCGAGCTGTCACACGGGGCAGCGAGTCAGGGACTGCGGAGCATCGCGCGATGTATTGTCTGACATGAATAACGGGTGTGTTTTGACACTTGAAACGCCTTGATCGCGGAAAGCATTCCGATGCTATGACAGTCGCTTCTTTTAAGGTATTTCGTATACCTTTAATTTAACACTATAGACTGCATTCTTGTTTGTTGTTATCCGGATACTGTTCATTGCAACAAGTGGAATTTTGGTGTGCAGACCACGATCCAGCTGTCATGGACGAGCAAAAGGATCAAAATAGTCGTGATTCGACTGAGTCTGAGAGCGTCTCGCTCTCACCCAATATACCATCTCCTCCGATTTTACCTCACCAGGCTGCGCAGCAAGCCCACAGAACCACGAACTTTTTCATCGACAATATTTTAAGGCCAGATTTCGGCTGCAAGAAAGATCCTGGGAGTAGGGATCGGGCGCAAACGTCGGGTAGGGAGAATGTTAACCCAATGGTAATAAGGCCGTCGCATAATAGCAGTCTTTGCCAGGATTCAAACTGCAGTAGTGACAGCACTTCTTCGTCCTCGTCGTCTTCGCCATCCTCAAAGCAGTCCTCGGTAAAGCATTTCGAAGGAAATGGATCTACCGCAGCAAGGAACGGGGAGAATACGCCGTCGATAATGATGGTGAACGCCAACGGGGGAACTCCGCCAGCTAAAGAATCACAGCCTTTACTATGGCCTGCGTGGGTGTACTGCACCAGGTACTCGGACAGACCTTCATCTG
>TCONS_00000175
GAAAGAGTTTGTTAAGCGCGAGCTGTCACACGGGGCAGCGAGTCAGGGACTGCGGAGCATCGCGCGATGTATTGTCTGACATGAATAACGGGTGTGTTTTGACACTTGAAACGCCTTGATCGCGGAAAGCATTCCGATGCTATGACAGTCGCTTCTTTTAAGGTATTTCGTATACCTTTAATTTAACACTATAGACTGCATTCTTGTTTGTTGTTATCCGGATACTGTTCATTGCAACAAGTGGAATTTTGGTGTGCAGACCACGATCCAGCTGTCATGGACGAGCAAAAGGATCAAAATAGTCGTGATTCGACTGAGTCTGAGAGCGTCTCGCTCTCACCCAATATACCATCTCCTCCGATTTTACCTCACCAGGCTGCGCAGCAAGCCCACAGAACCACGAACTTTTTCATCGACAATATTTTAAGGCCAGATTTCGGCTGCAAGAAAGATCCTGGGAGTAGGGATCGGGCGCAAACGTCGGGTAGGGAGAATGTTAACCCAATGGTAATAAGGCCGTCGCATAATAGCAGTCTTTGCCAGGATTCAAACTGCAGTAGTGACAGCACTTCTTCGTCCTCGTCGTCTTCGCCATCCTCAAAGCAGTCCTCGGTAAAGCATTTCGAAGGAAATGGATCTACCGCAGCAAGGAACGGGGAGAATACGCCGTCGATAATGATGGTGAACGCCAACGGGGGAACTCCGCCAGCTAAAGAATCACAGCCTTTACTATGGCCTGCGTGGGTGTACTGCACCAGGTACTCGGACAGACCTTCATCTGGCCCAAGGACACGAAaattgaaaaagaagaaaagcgAAAAGGAAGACAAGCGACCGAGAACTGCTTTCACGGCTGAACAGCTGCAGAGACTTAAAGCCGAGTTTCAGGCGAATCGGTACATTACGGAGCAGCGAAGACAGTCTCTGGCCCAGGAACTCAACCTCAATGAGTCGCAAATAAAAATCTGGTTCCAGAATAAGAGGGCCAAAATCAAAAAGGCTTCTGGCTATAAGAACGGCCTTGCTCTTCAGCTCATGGCTCAAGGACTCTACAACCATTCCACAACCACAGTTCAAGACGAAAAAGAAGATAGCGAATAAAAATGGCCCGGCTCATGTGTTTTAAAAAGGTCATGGACGCTGACCCCGACAgaagtgatttttcatatttttatgaatCAAATGAAAAGGAAATGTCTTCGAATTCTGCGAAACGAAGATGcgatatttaaacaaatttctgtTTATCAAACACTATATGGACATGCATCTAAATACGAACACTATGAAAATTTATATATAGCCAAAACTGTAAGATGTGTATATTTAATTCCAGGTAAGGGGATGTCTATATTGCTCCTTACTTGCTGAATATTTCTAACGTTTCTTCTCCTTTCCCAATGTGGTTGCTCACCGTTCCAGTAGGCCTAAGTGTCAGGCTTGTTAGTTTTTGTGATAGCCCTGTCTCTTAAATCCCTTATCTCACAGTTCTTCAAATGCGTGACTGAACCAACGCTTCAAGCCAAAGATTTTAATATGTTCAGATTATGTTGTCTGAAATAAAAAGGTAGAATGT

Function

symbol description
en1b Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within axonogenesis involved in innervation and neuron fate commitment. Predicted to be active in nucleus. Is expressed in myoseptum; nervous system; neural tube; and somite. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human EN1 (engrailed homeobox 1).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0060385 axonogenesis involved in innervation biological_process
GO:0030182 neuron differentiation biological_process
GO:0007275 multicellular organism development biological_process
GO:0048663 neuron fate commitment biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-980526-6 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within axonogenesis involved in innervation and neuron fate commitment. Predicted to be active in nucleus. Is expressed in myoseptum; nervous system; neural tube; and somite. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human EN1 (engrailed homeobox 1).

Ensembl:

ensembl_id ENSDARG00000098730

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000174 False 781 mRNA 0.49 1 7679328 7680108
TCONS_00000175 True 1576 mRNA 0.44 2 7679328 7683372

Neighbor

gene id symbol gene type direction distance location
XLOC_000087 NA coding upstream 5099 7672121 ~ 7674229 (+)
XLOC_000086 pcnp coding upstream 118106 7556965 ~ 7561222 (+)
XLOC_000085 lancl1 coding upstream 124865 7517449 ~ 7554463 (+)
XLOC_000084 NA coding upstream 166566 7512529 ~ 7512762 (+)
XLOC_000083 ERBB4 coding upstream 230533 7189856 ~ 7448795 (+)
XLOC_000089 CR855320.1 coding downstream 272658 7956030 ~ 7961696 (+)
XLOC_000090 CR855320.2 coding downstream 304680 7988052 ~ 7989314 (+)
XLOC_000091 SLC5A10 coding downstream 427190 8110562 ~ 8163167 (+)
XLOC_000092 cacna1hb coding downstream 621532 8304904 ~ 8404005 (+)
XLOC_000093 myo15ab coding downstream 758699 8442071 ~ 8507230 (+)
XLOC_000082 CABZ01075319.1 non-coding upstream 563414 7092273 ~ 7115914 (+)
XLOC_000081 CU929161.1 non-coding upstream 615385 7063837 ~ 7063943 (+)
XLOC_000080 NA non-coding upstream 689301 6956913 ~ 6990027 (+)
XLOC_000097 NA non-coding downstream 890405 8573777 ~ 8575057 (+)
XLOC_000098 AL928650.2 non-coding downstream 891935 8575307 ~ 8577274 (+)
XLOC_000100 NA non-coding downstream 903858 8587230 ~ 8590636 (+)
XLOC_000105 NA non-coding downstream 1267502 8950874 ~ 8965939 (+)
XLOC_000106 NA non-coding downstream 1284107 8967479 ~ 8976422 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G407340 NA non-coding CI01000299 null 4259482 ~ 4263461 (-)