XLOC_008919 (stx1a)


Basic Information

Item Value
gene id XLOC_008919
gene name stx1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 1734444 ~ 1746963 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00017615
ATGAATCTCCTCACGACTTTCTGTATTTCTATTCATCAGGGAAAAGAGCTGGAAGAGCAGAATGAGGTGACTATGAACAATAAAATGGTGATTGAAGATGGCTTTATGGATGAGTTCTTTGAGCAGGTTGAAGAGATTCGGGAGTTCATCGACTCTTTGGCAGAGAAAGTAGGAGAAGTGAAGAGAAACCATAGCGCCACACTGGCCTCCCCAAACCCAGATGAGAaaacaaaaacagagttTGAGGAACTGATGAACGATATCAAGACGTTGGCTAATAAAGTGCGCTCCAGGTTACAGCGTGAGTTTGTCATCTTTAATAGCACACAACACTCCACCCTGTCACGTAAATTTGTAGAGGTGATGTCGGAGTATAATGCAGCACAATCAGAATACAGGGAACGATGCAAAGGACGGATACAGAGACAGCTTGAGATCACAGGTAGAAAGACAACAAAAGAGGAGTTGGAGACCATATTGGAAAGTGACAACCCATCCATCTTCACAACAGGGgTCTTCATGGACTGCAGCATCACTAAACAGGCCATGAATGAGATCGAGACACGACACAATGAAATCATCCAGTTGGAGAGCTGCATCCGAGAGCTTCAGGATATGTTTGTGGATTTGGCCGTGCTGGTGGAGAACCAGGGAGAGTTAATTAACAATATAGAGACAAACGTCTCCAGTGCTCAGGAATATGTGGAGAAGGCTAAAGAGGAAACCAAAGCGGCTATTAAAATCCAGAAGACTAGCAGAACGAAGTTGATCCTGATCGGCGGCTGTGTGTCCGTCTGTGTTCTCATACTCATCATCGCCCTCATCTTTGGactgacataa
>TCONS_00017616
ATGAAGGACCGCACACAGGAGCTCAGACATGGAAAAGAGCTGGAAGAGCAGAATGAGGTGACTATGAACAATAAAATGGTGATTGAAGATGGCTTTATGGATGAGTTCTTTGAGCAGGTTGAAGAGATTCGGGAGTTCATCGACTCTTTGGCAGAGAAAGTAGGAGAAGTGAAGAGAAACCATAGCGCCACACTGGCCTCCCCAAACCCAGATGAGAaaacaaaaacagagttTGAGGAACTGATGAACGATATCAAGACGTTGGCTAATAAAGTGCGCTCCAGGTTACAGCATATCCAGCAGAGCATAGAGCATGAGGAGGCATTTAATGGTCAATCAGCTGATGTGAGGATACGAAAAACACAGCACTCCACCCTGTCACGTAAATTTGTAGAGGTGATGTCGGAGTATAATGCAGCACAATCAGAATACAGGGAACGATGCAAAGGACGGATACAGAGACAGCTTGAGATCACAGGTAGAAAGACAACAAAAGAGGAGTTGGAGACCATATTGGAAAGTGACAACCCATCCATCTTCACAACAGGGgTCTTCATGGACTGCAGCATCACTAAACAGGCCATGAATGAGATCGAGACACGACACAATGAAATCATCCAGTTGGAGAGCTGCATCCGAGAGCTTCAGGATATGTTTGTGGATTTGGCCGTGCTGGTGGAGAACCAGGGAGAGTTAATTAACAATATAGAGACAAACGTCTCCAGTGCTCAGGAATATGTGGAGAAGGCTAAAGAGGAAACCAAAGCGGCTATTAAAATCCAGAAGACTAGCAGAACGAAGTTGATCCTGATCGGCGGCTGTGTGTCCGTCTGTGTTCTCATACTCATCATCGCCCTCATCTTTGGa

Function

symbol description
stx1a Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to act upstream of or within neurotransmitter transport; regulation of exocytosis; and vesicle-mediated transport. Predicted to be located in membrane. Predicted to be part of SNARE complex. Predicted to be active in presynaptic active zone membrane and synaptic vesicle. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Creutzfeldt-Jakob disease and Hirschsprung's disease. Orthologous to human STX1A (syntaxin 1A).

GO:

id name namespace
GO:0006886 intracellular protein transport biological_process
GO:0006887 exocytosis biological_process
GO:0006906 vesicle fusion biological_process
GO:0048278 vesicle docking biological_process
GO:0016192 vesicle-mediated transport biological_process
GO:0017157 regulation of exocytosis biological_process
GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane biological_process
GO:0042734 presynaptic membrane cellular_component
GO:0048787 presynaptic active zone membrane cellular_component
GO:0005886 plasma membrane cellular_component
GO:0012505 endomembrane system cellular_component
GO:0008021 synaptic vesicle cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0031201 SNARE complex cellular_component
GO:0005484 SNAP receptor activity molecular_function
GO:0000149 SNARE binding molecular_function

KEGG:

id description
ko04130 SNARE interactions in vesicular transport
ko04911 Insulin secretion
ko04721 Synaptic vesicle cycle
ko05016 Huntington disease
ko05022 Pathways of neurodegeneration - multiple diseases
ko05031 Amphetamine addiction
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-100802-1 Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to act upstream of or within neurotransmitter transport; regulation of exocytosis; and vesicle-mediated transport. Predicted to be located in membrane. Predicted to be part of SNARE complex. Predicted to be active in presynaptic active zone membrane and synaptic vesicle. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Creutzfeldt-Jakob disease and Hirschsprung's disease. Orthologous to human STX1A (syntaxin 1A).

Ensembl:

ensembl_id ENSDARG00000058994

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00017615 False 840 mRNA 0.45 8 1734444 1745408
TCONS_00017616 True 867 mRNA 0.46 10 1734453 1746963

Neighbor

gene id symbol gene type direction distance location
XLOC_008918 rabgef1l coding downstream 1185 1718668 ~ 1733259 (-)
XLOC_008917 sptssb coding downstream 47240 1679962 ~ 1687204 (-)
XLOC_008916 ppm1lb coding downstream 82678 1630815 ~ 1651766 (-)
XLOC_008915 kpna4 coding downstream 111959 1596508 ~ 1622485 (-)
XLOC_008914 nnr coding downstream 143586 1589813 ~ 1590858 (-)
XLOC_008920 bud23 coding upstream 2880 1749843 ~ 1765137 (-)
XLOC_008921 mmp28 coding upstream 31810 1778773 ~ 1822548 (-)
XLOC_008922 taf15 coding upstream 78209 1825172 ~ 1844048 (-)
XLOC_008923 porb coding upstream 100172 1847135 ~ 1885247 (-)
XLOC_008924 dock10 coding upstream 150412 1897375 ~ 2010926 (-)
XLOC_008910 LO017713.1 non-coding downstream 412538 1321790 ~ 1321906 (-)
XLOC_008908 NA non-coding downstream 591375 1140445 ~ 1143069 (-)
XLOC_008903 NA non-coding downstream 726085 1007600 ~ 1008359 (-)
XLOC_008902 NA non-coding downstream 740857 986144 ~ 993587 (-)
XLOC_008899 NA non-coding downstream 833565 899089 ~ 900879 (-)
XLOC_008927 AL954387.2 non-coding upstream 519006 2265969 ~ 2266083 (-)
XLOC_008928 NA non-coding upstream 576703 2323666 ~ 2328284 (-)
XLOC_008932 NA non-coding upstream 851841 2598804 ~ 2611170 (-)
XLOC_008933 NA non-coding upstream 871316 2618279 ~ 2625928 (-)
XLOC_008940 CABZ01086049.1 non-coding upstream 989420 2736383 ~ 2736498 (-)

Expression


Co-expression Network