XLOC_000914 (pros1)


Basic Information

Item Value
gene id XLOC_000914
gene name pros1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 343292 ~ 354166 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001453
CCACCCGCCTCCTAAAGCGCACTGACCAGCTGAGCGCTACTAGTTCCCTCATGGTTAACCCACACACACGCCGGCCAGGCATGAGCTCTGTCTGCCAGAAACACTAGAGGAAAGTCAACAGGAAAAGCGAGTGTTTGGATCCGAGACACCGAAGCGGAAGCGACTGGAACTTCAGCGGGACATGAGGAGTCTGAAGGCGGCGTGCAGCGGCTCGGAGCTcggcctgctgctgctgctgctgtccgCTACACTCTGCGGCTCTCAGCGCTttcttCCTCAGAGTAAAGCGTCAGAGTTCCTGCTGCGTCACAGACGGGCGAACACACTCTTTGAGGAGAGTAAGAAAGGAAACCTGGAGCGCGAGTGTATCGAGGAGCTCTGCAATAAAGAGGAGGCGCGCGAGATCTTCGAGAACAACCTGGAGACGGAATATTTCTACCCCAGGTATGTTGtgtgTTTAGGTTCTCACCGTGTGGGCATCAATAATCCGGAGCCGGGCATTCCTCAGAATCTGCGCACGTGTGTTGAAGagatcAGTAATCAGTGTTTGCCGCCACCGTGTTATAAAGAAGGCTCCGAGCGCTGTGTGGATGGCCAGGGCTCCTACAGGTGTGTGTGTAAACCTGGATGGAGAGGACAGCGCTGTGAGCAGGacaTTGATGAGTGTGAGGACCCAGAGTTCCCGGCGGGCTGCAGTCAGACCTGCTTCAATCTGCCCGGCAGCTTCACCTGCGGCTGTGAGAGCGGCTACTACACCAATGATGGAGTACACTGCAtcgatatCGACGAGTGTGTGCTGTTCCCCAGTGTGTGTGTGGAACCGTCCAAATGCATCAACGCTCCGGGGACATTCGAGTGCCGCTGTCAGCTGGGATACACTTACAACATGAGCTCACACACGTGTGtcgatgtggACGAGTGTTTGGAGGACGCGTGTGCTGGCGAGTGTGTGAACGCGGTGGGCAGTTTCTCCTGTCAGTGTGACGGGCGCAGGGGTCTTCAGCTGGATGAGGACGGTCTCGGCTGCGTCTCAATCCCCCAGTGTCTGCAACTGTACGATCACAAACACAAGGAGATGCTGTACCTGGGGGAGCAGTTCAGCGGTCTGCCCGTCATCTACCTGCGCTTCAGACTGCAGCCGCACAccagGTTTGCGGCTGAGTTTGATTTCCGCACGTTTGACCCAGAAGGCGTGATTCTGTACGCCGAGTCGTCACCCGACTCCTGGATCATGCTGGGTTTGCGGAGCGGACGAATCGAAGTCCAGTTTAAGAACGAACACTCCATTAAGATGACCAGCGGAGGGAAAGCCATCAATGACGGACAGTGGCACGTGATCTCAGTGGAGGAGCTGTCGGGCAGCATCAGTGTGAAGATCAGTAAAGAGGCTGTGATGAGCATCAACAGTCCTGAGCGTCTCTTTACTCCCGTTAATGACAAGCTGGAGACTAAAGTGTACATCGCCGGCCTGCCCAACCACAACCAGAGCCTCATCAAAACGATCAACCCTCGGCTGGACGGCTGCATCCGCGGCTGGAACCTCATGAACCAGGGAGCGTCCGGGGTGAAGGAGGTCATCCAGGAGAAGGAGAGCAAACACTGCTATGTGCATGTGGAGAAGGGCTCGTTCTTCAGCGGAGGAGGACACGCGCTCTTCAACATCGACTACAgtgtTTCAGGTCAGTGGAAGCTGGATGTGGTGATGAGTCTGCGTCCGTCCAGCACCACAGGGGTGATCTTGGCTCTGGTCTCCAACAACACCGTCCCGCTGCTGGTGGCCGTGGTCTCCCTAGGGCCGGATGatgctgagctGCAGGTGCTGCTGGACGGTGTGTGTGTAGCGACGCTGCAGTCTCTGATGCTCTGTTATCCTGATCGTCTGGTTGTGGAGCTCAGAGCTTCAGCCGAGGGGCTCCAGATCTCCGCGAACTCCTCCAGCGTGTCTTACAGCGAGCCGCAGACTCTGAGCGCCGCCCTGCACAAGCTGGATACAGCCATGCACACACAACCGCAGACGTACATCGGTGGACTGCCAGatctgCCGCTGTCCATCACACCAGTCTCCGCCTTCTATCACGGTTGTCTGGAGCTCGTTATTGGTGGTCGGCAGCTGGATTTTGATGAAGCCGTCAGTAAAGACAACAGCATCAAATCTCACTCCTGCCCTCCGTACTCCATTACCCAATCTCCATCTGCACCATGagcaggaagtgacatcactggAGAGGAGGAGTGTATTTTAACTGATCCGCTCATCACACTGCAACAAATGCCTTTATTATTTAGAGTTTGtgtctggtttctagtccaaatatgtttGCTTGTgatgaaaatgcttcttgattttaagaGATTTTGACATTTGGACTGGAAACTCTACTTACGGAAGCATTTCTGCAGTGTGTTGACTGGAGACTAGCCTGTGGAGCCTTCATTTACACACCATCAGTGTTCATACTGTTCCTCACGTCTGATTTTAGTCAGGTTTTTACACTAAACTGTGCGTATAGAGCCGTGTCTTGTATATAACACTCTGATTTTAAAGTGCTGTGAATATGATGAGCAGTGATTGAACAATAGTGTTactgtaattgttttaataaaaccttAAAATTCA
>TCONS_00001454
ggtcGGAGCACCAGTGTTTTAACTGACACATTTCTGATGATGTGTTGAACTTGTGTTTCAGATCAACCCTCGGCTGGACGGCTGCATCCGCGGCTGGAACCTCATGAACCAGGGAGCGTCCGGGGTGAAGGAGGTCATCCAGGAGAAGGAGAGCAAACACTGCTATGTGCATGTGGAGAAGGGCTCGTTCTTCAGCGGAGGAGGACACGCGCTCTTCAACATCGACTACAgtgtTTCAGGTCAGTGGAAGCTGGATGTGGTGATGAGTCTGCGTCCGTCCAGCACCACAGGGGTGATCTTGGCTCTGGTCTCCAACAACACCGTCCCGCTGCTGGTGGCCGTGGTCTCCCTAGGGCCGGATGatgctgagctGCAGGTGCTGCTGGACGGTGTGTGTGTAGCGACGCTGCAGTCTCTGATGCTCTGTTATCCTGATCGTCTGGTTGTGGAGCTCAGAGCTTCAGCCGAGGGGCTCCAGATCTCCGCGAACTCCTCCAGCGTGTCTTACAGCGAGCCGCAGACTCTGAGCGCCGCCCTGCACAAGCTGGATACAGCCATGCACACACAACCGCAGACGTACATCGGTGGACTGCCAGatctgCCGCTGTCCATCACACCAGTCTCCGCCTTCTATCACGGTTGTCTGGAGCTCGTTATTGGTGGTCGGCAGCTGGATTTTGATGAAGCCGTCAGTAAAGACAACAGCATCAAATCTCACTCCTGCCCTCCGTACTCCATTACCCAATCTCCATCTGCACCATGagcaggaagtgacatcactggAGAGGAGGAGTGTATTTTAACTGATCCGCTCATCACACTGCAACAAATGCCTTTATTATTTAGAGTTTG
>TCONS_00001455
TGGTTAACCCACACACACGCCGGCCAGGCATGAGCTCTGTCTGCCAGAAACACTAGAGGAAAGTCAACAGGAAAAGCGAGTGTTTGGATCCGAGACACCGAAGCGGAAGCGACTGGAACTTCAGCGGGACATGAGGAGTCTGAAGGCGGCGTGCAGCGGCTCGGAGCTcggcctgctgctgctgctgctgtccgCTACACTCTGCGGCTCTCAGCGCTttcttCCTCAGAGTAAAGCGTCAGAGTTCCTGCTGCGTCACAGACGGGCGAACACACTCTTTGAGGAGAGTAAGAAAGGAAACCTGGAGCGCGAGTGTATCGAGGAGCTCTGCAATAAAGAGGAGGCGCGCGAGATCTTCGAGAACAACCTGGAGACGGAATATTTCTACCCCAGtgtgTTTAGGTTCTCACCGTGTGGGCATCAATAATCCGGAGCCGGGCATTCCTCAGAATCTGCGCACGTGTGTTGAAGagatcAGTAATCAGTGTTTGCCGCCACCGTGTTATAAAGAAGGCTCCGAGCGCTGTGTGGATGGCCA

Function

symbol description
pros1 Predicted to enable calcium ion binding activity. Predicted to act upstream of or within blood coagulation and fibrinolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in hypochord. Human ortholog(s) of this gene implicated in autosomal dominant thrombophilia due to protein S deficiency; autosomal recessive thrombophilia due to protein S deficiency; cerebral infarction; and protein S deficiency. Orthologous to human PROS1 (protein S).

GO:

id name namespace
GO:0030195 negative regulation of blood coagulation biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005509 calcium ion binding molecular_function

KEGG:

id description
ko04610 Complement and coagulation cascades

ZFIN:

id description
ZDB-GENE-061013-657 Predicted to enable calcium ion binding activity. Predicted to act upstream of or within blood coagulation and fibrinolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in hypochord. Human ortholog(s) of this gene implicated in autosomal dominant thrombophilia due to protein S deficiency; autosomal recessive thrombophilia due to protein S deficiency; cerebral infarction; and protein S deficiency. Orthologous to human PROS1 (protein S).

Ensembl:

ensembl_id ENSDARG00000068261

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001453 False 2617 mRNA 0.53 14 343292 354166
TCONS_00001454 False 852 lncRNA 0.55 4 343617 345895
TCONS_00001455 True 538 mRNA 0.55 5 350840 354115

Neighbor

gene id symbol gene type direction distance location
XLOC_000913 gas6 coding downstream 4847 312784 ~ 338445 (-)
XLOC_000912 dcun1d2b coding downstream 128381 208181 ~ 214911 (-)
XLOC_000910 FO681286.1 coding downstream 137084 160302 ~ 206208 (-)
XLOC_000911 grtp1a coding downstream 151259 184915 ~ 192033 (-)
XLOC_000909 pcid2 coding downstream 185729 152007 ~ 157563 (-)
XLOC_000915 rasa3 coding upstream 3352 357518 ~ 411331 (-)
XLOC_000916 METTL21C coding upstream 100149 454315 ~ 462165 (-)
XLOC_000917 zgc:92518 coding upstream 112614 466780 ~ 471925 (-)
XLOC_000918 ercc5 coding upstream 119919 474085 ~ 494280 (-)
XLOC_000919 trmt10c coding upstream 154719 508885 ~ 513786 (-)
XLOC_000907 FP067451.1 non-coding downstream 195446 108285 ~ 147846 (-)
XLOC_000927 NA non-coding upstream 424409 778575 ~ 779614 (-)
XLOC_000929 NA non-coding upstream 651771 1005937 ~ 1014866 (-)
XLOC_000930 CU611053.1 non-coding upstream 696775 1050941 ~ 1051057 (-)
XLOC_000931 NA non-coding upstream 789796 1143962 ~ 1253194 (-)
XLOC_000932 NA non-coding upstream 937009 1291175 ~ 1315753 (-)

Expression


Co-expression Network