XLOC_009898 (apoeb)


Basic Information

Item Value
gene id XLOC_009898
gene name apoeb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 23960744 ~ 23963461 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019750
GAAAAGATGCGGACTTCGCACAGTTGCTGCAGTCAGTGACGCGTGGGATGATGCGCGAGCCCCGAACAAAAGACGAATCACGTGGCTGCGATTGTGAATACAGCGGGTGCGTCCCGGGACAGTATAAAAGACCTGCCATCCAAACTGCTCCACACGGAGAAAAATCACGCTTCTCAGGTGTTCTTGTCTGTCCATCAACATGAGGTCTCTTGTGGTATTCTTTGCTCTGGCAGTTTTAACtgGCTGCCAGGCTCGTAGCCTGTTCCAGGCTGATGCCCCTCAGCCCAGATGGGAGGAGATGGTGGACCGTTTCTGGCAGTATGTGTCTGAACTCAACACACAAACTGACGGCATGGTGCAAAACATCAAGGGCTCCCAGCTCAGCAGAGAGCTTGACACACTAATTACTGACACCATGGCTGAACTGAGCTCATACAGTGAAAATCTCCAAACCCAGATGACCCCATACGCCTCTGATGCTGCTGGTCAGCTCAGTAAAGATCTTCAGCTCCTGGCTGGAAAACTCCAAACTGACATGACCGACGCTAAGGAACGCAGCACTCAGTACCTGCAAGAGCTGAAGACCATGATGGAGCAGAATGCAGATGACGTGAAGAACCGTGTCGGCACCTACACACGCAAACTGAAGAAACGCCTGAACAAGGACACAGAGGAGATCCGCAACACCGTAGCAACCTACATGAGTGAGATGCAGTCCCGCGCTTCCCAAAATGCTGATGCAGTGAAGGACCGTTTCCAGCCATACATGAGCCAGGCCCAGGATGGCGCCACCCAGAAACTGGGCGCCATTAGCGAGCTGATGAAGGCCCAGGCGCAGGAGGTGAGCGAGCAGTTGGAGGTCCAGGCTGGAGCTCTGAAGGAGAAGCTGGAGGAGACAGCCGAGAACCTACGCACCTCTCTGGAGGGCCGTGTGGATGAGCTGACCAGCCTCCTCGCCCCCTACTCCCAGAAGATCCGCGAGCAGCTGCAGGAAGTCATGGACAAGATCAAGGAGGCCACAGCAGCTCTTCCCACTCAGGCTTAAGAGCTCCACACTTACCTAGTGTTAACACCAAACAGAAAGAAGAAGGGAGGCTTTGTGTTACTGAAATGTGCTTTTTTCATTCTGTGAGAGGTTGATAAAGTGGTTAACAACTGGACTCAATTGGACTAGCACTGTCCTTTACTGGACAAAAGAAATGCCATGTACTCACCACGTTTACTTTCTCAGTATTAACCCATGTCTGAGGATATATTTCTGTTAGCGTACAGTAGAGCGAATTTAAGATCAATCAACTTGCCTGTCTTGGAGGCTAGTTTTTCTAGTTAGTGGGGCCAAACGTGGCGTCATTCAAAATAAATAGTAATCAAAAGGTGCCTTCAGCTGCTGAAATGAATCAGAACACATGAAAGATGAGCTTTGTTAGTCAACAGTCCACATATAAATGCTTGTTTACTTTACATGTTTGTGCACTGATGTGTTTGAATTTGTTTGCAATAAATGTGCGTTCTACTACACAA
>TCONS_00019751
AAGACCTGCCATCCAAACTGCTCCACACGGAGAAAAATCACGCTTCTCAGGTGTTCTTGTCTGTCCATCAACATGAGGTCTCTTGTGGTATTCTTTGCTCTGGCAGTTTTAACtgTCTCTTCTCACCTCTTGTAGGCTGCCAGGCTCGTAGCCTGTTCCAGGCTGATGCCCCTCAGCCCAGATGGGAGGAGATGGTGGACCGTTTCTGGCAGTATGTGTCTGAACTCAACACACAAACTGACGGCATGGTGCAAAACATCAAGGGCTCCCAGCTCAGCAGAGAGCTTGACACACTAATTACTGACACCATGGCTGAACTGAGCTCATACAGTGAAAATCTCCAAACCCAGATGACCCCATACGCCTCTGATGCTGCTGGTCAGCTCAGTAAAGATCTTCAGCTCCTGGCTGGAAAACTCCAAACTGACATGACCGACGCTAAGGAACGCAGCACTCAGTACCTGCAAGAGCTGAAGACCATGATGGAGCAGAATGCAGATGACGTGAAGAACCGTGTCGGCACCTACACACGCAAACTGAAGAAACGCCTGAACAAGGACACAGAGGAGATCCGCAACACCGTAGCAACCTACATGAGTGAGATGCAGTCCCGCGCTTCCCAAAATGCTGATGCAGTGAAGGACCGTTTCCAGCCATACATGAGCCAGGCCCAGGATGGCGCCACCCAGAAACTGGGCGCCATTAGCGAGCTGATGAAGGCCCAGGCGCAGGAGGTGAGCGAGCAGTTGGAGGTCCAGGCTGGAGCTCTGAAGGAGAAGCTGGAGGAGACAGCCGAGAACCTACGCACCTCTCTGGAGGGCCGTGTGGATGAGCTGACCAGCCTCCTCGCCCCCTACTCCCAGAAGATCCGCGAGCAGCTGC
>TCONS_00019752
CACGCTTCTCAGGTGTTCTTGTCTGTCCATCAACATGAGGTCTCTTGTGGTATTCTTTGCTCTGGCAGTTTTAACtgGCTGCCAGGCTCGTAGCCTGTTCCAGGCTGATGCCCCTCAGCCCAGATGGGAGGAGATGGTGGACCGTTTCTGGCAGTATGTGTCTGAACTCAACACACAAACTGACGGCATGGTGCAAAACATCAAGGGCTCCCAGCTCAGCAGAGAGCTTGACACACTAATTACTGACACCATGGCTGAACTGAGCTCATACAGTGAAAATCTCCAAACCCAGATGACCCCATACGCCTCTGATGCTGCTGGTCAGCTCAGTAAAGATCTTCAGCTCCTGGCTGGAAAACTCCAAACTGACATGACCGACGCTAAGGAACGCAGCACTCAGTACCTGCAAGAGCTGAAGACCATGATGGAGCAGAATGCAGATGACGTGAAGAACCGTGTCGGCACCTACACACGCAAACTGAAGAAACGCCTGAACAAGGACACAGAGGAGATCCGCAAGTAAGTTGGGATGCTCCTTCAGGTGGCTTACGagaaaaccctttttttttttttttttttttagctatttttgGTATTATTTAATCCATTCACGTCCAGGTCTGGCCAGAgaaacttttagcttagcataaattatagAATCAAatttgaccattagcatcttgctcaaaaaaaaaaaaaagagttttgataaattTCCTTTTAAAGCTTGcttcttctgtagttacatcatgtattaagacctacataaaaataaacgttgctattttctaggcaaatatatctagtaaaagataAGCGTAAAGCTTAAAATAGAAAACTCTTTGAGCGCAATGCTAATAGTTTAACCCgcttcaataatctatgctaaaatAAGAT
>TCONS_00019753
CGCTCTTTACTCGTGGACTCATCATCCTCTTATTACAGAAGGGTTTATGGAGAAGAAAACTAGcttaactgtaaaaaatattgcgTACTACACTTACAGTTAGCTTAATATTTATGCAATGTTTTAACGCGTTATGGATCGGTGTCGTCGTATCTCAGATGATGTTTTGAAGATGATTTGTATACGTTTAAAATCGTGTGTTCTTGTCTGTCCATCAACATGAGGTCTCTTGTGGTATTCTTTGCTCTGGCAGTTTTAACtgGCTGCCAGGCTCGTAGCCTGTTCCAGGCTGATGCCCCTCAGCCCAGATGGGAGGAGATGGTGGACCGTTTCTGGCAGTATGTGTCTGAACTCAACACACAAACTGACGGCATGGTGCAAAACATCAAGGGCTCCCAGCTCAGCAGAGAGCTTGACACACTAATTACTGACACCATGGCTGAACTGAGCTCATACAGTGAAAATCTCCAAACCCAGATGACCCCATACGCCTCTGATGCTGCTGGTCAGCTCAGTAAAGATCTTCAGCTCCTGGCTGGAAAACTCCAAACTGACATGACCGACGCTAAGGAACGCAGCACTCAGTACCTGCAAGAGCTGAAGACCATGATGGAGCAGAATGCAGATGACGTGAAGAACCGTGTCGGCACCTACACACGCAAACTGAAGAAACGCCTGAACAAGGACACAGAGGAGATCCGCAACACCGTAGCAACCTACATGAGTGAGATGCAGTCCCGCGCTTCCCAAAATGCTGATGCAGTGAAGGACCGTTTCCAGCCATACATGAGCCAGGCCCAGGATGGCGCCACCCAGAAACTGGGCGCCATTAGCGAGCTGATGAAG
>TCONS_00019754
ATCAACATGAGGTCTCTTGTGGTATTCTTTGCTCTGGCAGTTTTAACtgGCTGCCAGGCTCGTAGCCTGTTCCAGGCTGATGCCCCTCAGCCCAGATGGGAGGAGATGGTGGACCGTTTCTGGCAGTATGTGTCTGAACTCAACACACAAACTGACGGCATGGTGCAAAACATCAAGGGCTCCCAGCTCAGCAGAGAGCTTGACACACTAATTACTGACACCATGGCTGAACTGAGCTCATACAGTGAAAATCTCCAAACCCAGATGACCCCATACGCCTCTGATGCTGCTGGTCAGCTCAGTAAAGATCTTCAGCTCCTGGCTGGAAAACTCCAAACTGACATGACCGACGCTAAGGAACGCAGCACTCAGTACCTGCAAGAGCTGAAGACCATGATGGAGCAGAATGCAGATGACGTGAAGAACCGTGTCGGCACCTACACACGCAAACTGAAGAAACGCCTGAACAAGGACACAGAGGAGATCCGCAACACCGTAGCAACCTACATGAGTGAGATGCAGTCCCGCGCTTCCCAAAATGCTGATGCAGTGAAGGACCGTTTCCAGCCATACATGAGCCAGGCCCAGGATGGCGCCACCCAGAAACTGGGCGCCATTAGCGAGCTGATGAAGGCCCAGGCGCAGGAGGTGAGCGAGCAGTTGGAGGTCCAGGCTGGAGCTCTGAAGGAGAAGCTGGAGGAGACAGCCGAGAACCTACGCACCTCTCTGGAGGGCCGTGTGGATGAGCTGACCAGCCTCCTCGCCCCCTACTCCCAGAAGATCCGCGAGCAGCTGCAGGAAGTCATGGACAAGATCAAGGAGGCCACAGCAGCTCTTCCCACTCAGGCTTAAGAGCTCCACACTTACCTAGTGTTAACACCAAACAGAAAGAAGAAGGGAGGCTTTGTGTTACTGAAATGTGCTTTTTTCATTCTGTGAGAGGTTGATAAAGTGGTTAACAACTGGACTCAATTGGACTAGCACTGTCCTTTACTGGACAAAAGAAATGCCATGTACTCACCACGTTTACTTTCTCAGTATTAACCCATGTCTGAGGATATATTTCTGTTAGCGTACAGTAGAGCGAATTTAAGATCAATCAACTTGCCTGTCTTGGAGGCTAGTTTTTCTAGTTAGTGGGGCCAAACGTGGCGTCATTCAAAATAAATAGTAATCAAAAGGTGCCTTCAGCTGCTGAAATGAATCAGAACACATGAAAGATGAGCTTTGTTAGTCAACAGTCCACATATAAATGCTTGTTTACTTTACATGTTTGTGCACTGATGTGTTTGAATTTGTTTGCAATAAATGTGCGTTCTACTAC

Function

symbol description
apoeb Predicted to enable several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and low-density lipoprotein particle receptor binding activity. Predicted to be involved in several processes, including cholesterol catabolic process; lipoprotein metabolic process; and triglyceride-rich lipoprotein particle clearance. Predicted to act upstream of or within lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular matrix and extracellular space. Predicted to be part of high-density lipoprotein particle; low-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Is expressed in several structures, including digestive system; epidermis; fin bud; median fin; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); artery disease (multiple); biliary tract cancer (multiple); eye disease (multiple); and familial hyperlipidemia (multiple). Orthologous to human APOE (apolipoprotein E).

GO:

id name namespace
GO:0034447 very-low-density lipoprotein particle clearance biological_process
GO:0071831 intermediate-density lipoprotein particle clearance biological_process
GO:1900221 regulation of amyloid-beta clearance biological_process
GO:0042157 lipoprotein metabolic process biological_process
GO:0042158 lipoprotein biosynthetic process biological_process
GO:0042159 lipoprotein catabolic process biological_process
GO:0006707 cholesterol catabolic process biological_process
GO:0051000 positive regulation of nitric-oxide synthase activity biological_process
GO:0034380 high-density lipoprotein particle assembly biological_process
GO:0034382 chylomicron remnant clearance biological_process
GO:0033344 cholesterol efflux biological_process
GO:0043524 negative regulation of neuron apoptotic process biological_process
GO:0006869 lipid transport biological_process
GO:0031012 extracellular matrix cellular_component
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0034361 very-low-density lipoprotein particle cellular_component
GO:0034362 low-density lipoprotein particle cellular_component
GO:0034363 intermediate-density lipoprotein particle cellular_component
GO:0034364 high-density lipoprotein particle cellular_component
GO:0008201 heparin binding molecular_function
GO:0042802 identical protein binding molecular_function
GO:0043395 heparan sulfate proteoglycan binding molecular_function
GO:0050750 low-density lipoprotein particle receptor binding molecular_function
GO:0008289 lipid binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-980526-368 Predicted to enable several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and low-density lipoprotein particle receptor binding activity. Predicted to be involved in several processes, including cholesterol catabolic process; lipoprotein metabolic process; and triglyceride-rich lipoprotein particle clearance. Predicted to act upstream of or within lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular matrix and extracellular space. Predicted to be part of high-density lipoprotein particle; low-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Is expressed in several structures, including digestive system; epidermis; fin bud; median fin; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); artery disease (multiple); biliary tract cancer (multiple); eye disease (multiple); and familial hyperlipidemia (multiple). Orthologous to human APOE (apolipoprotein E).

Ensembl:

ensembl_id ENSDARG00000040295

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019750 False 1521 mRNA 0.50 5 23960744 23963461
TCONS_00019751 False 882 processed_transcript 0.55 5 23960871 23962929
TCONS_00019752 False 897 lncRNA 0.42 4 23960909 23962471
TCONS_00019753 False 846 mRNA 0.48 5 23960933 23962766
TCONS_00019754 True 1324 mRNA 0.49 4 23961276 23963457

Neighbor

gene id symbol gene type direction distance location
XLOC_009897 apoa4b.2 coding upstream 12206 23947196 ~ 23948538 (+)
XLOC_009896 si:dkey-7f3.14 coding upstream 35899 23923746 ~ 23924845 (+)
XLOC_009895 apoa4b.2 coding upstream 37876 23921610 ~ 23922868 (+)
XLOC_009894 apoa4b.1 coding upstream 44481 23913943 ~ 23916263 (+)
XLOC_009893 gtpbp10 coding upstream 58305 23891443 ~ 23902439 (+)
XLOC_009899 apoc1 coding downstream 8665 23972126 ~ 23973721 (+)
XLOC_009900 apoa2 coding downstream 15517 23978978 ~ 23980354 (+)
XLOC_009901 apoc2 coding downstream 20718 23984179 ~ 23994642 (+)
XLOC_009902 NA coding downstream 55647 24019108 ~ 24028618 (+)
XLOC_009903 NA coding downstream 235018 24198479 ~ 24207903 (+)
XLOC_009889 CR533578.1 non-coding upstream 353392 23607231 ~ 23607352 (+)
XLOC_009875 NA non-coding upstream 1264248 22695226 ~ 22696496 (+)
XLOC_009872 NA non-coding upstream 1381418 22575143 ~ 22579326 (+)
XLOC_009870 NA non-coding upstream 1631716 22327970 ~ 22329028 (+)
XLOC_009869 NA non-coding upstream 1633242 22323766 ~ 22327502 (+)
XLOC_009904 CT867948.1 non-coding downstream 552631 24516092 ~ 24524076 (+)
XLOC_009905 NA non-coding downstream 602273 24565734 ~ 24573801 (+)
XLOC_009910 NA non-coding downstream 871314 24834775 ~ 24897111 (+)

Expression


Co-expression Network