XLOC_023962 (shank2b)


Basic Information

Item Value
gene id XLOC_023962
gene name shank2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007136.7
NCBI id CM002909.2
chromosome length 37502051
location 14165447 ~ 14366077 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00047581
tttgGATCATGCCGCGGAGCCCCATGTCTAGTGAGGAGGAAATGGCTCAGAGTTTTTCCGACTCGGTCAGTTCAGACTCAGACAGCTCCCGAGATGAGCCTCCGAGGCTGGACCGACCGACCAGTGGCCGTCAGGACAACAACACTACGCTTATCTGTGTGGTCATCCCTGACCTGCAGCAGTCtAAATCCATGCGCTTCAGTCCTGATGCCACCGTGTGGGTTGCTAAGCAGCAGATCCTGTGTACCCTCACCCAGAGCCTGCGGGACGTGCTCAACTACGGCCTCTTCCAGCCGGCGGTGGACGGCAGGGAAAGCGGATTCCTGGAAGAAGAGCGGCTGCTCAGAGACTATCCGCTATCCTCCACTAAAGGCATCCCCACTCTTGAGTTTCGCTACAAGAGCAGAGTGTACCAGCAGCCAAATGTCAACGAAAAGCAAATCGAAAAGCTCCACACACAGgtcaacctGAGGAAGTTTATGGAGTACATTCAGCATCATCAGGTGGAGAAAGTGGCCAAGATGTTGGAGAGAGGGCTGGATCCCAACTATCATGACCCTGATACTGGTGAGACCCCGCTGACCCTTGCTGCTCACTTGGACAATATGCTGGAGATTATAGTGACTCTAAAGAACGGCGGGGCTCATTTGGACTTTCGCTCCCGGGATGGCATGACTGCCCTGCACAAAGCAGCCAGAGCCAAAAACCAGATCGCTCTCAAGACAATGTTAGATTTGGGAGCATCTCCAGACTATAAAGACCGGCAGGGTTTGACCCCGCTGTACCACACGGTGACAGTAGGTGGCGACCCCAGCTGCTGTGAGGTCCTGCTGCGTGCCCATGCCAGCGTCGGGTGCCATGATGAAAACGGCTGGCACGAGATCCACCAGGCATGTCGATACGGACACGTCCAGCATCTGGAGCATCTGTTGTTTTACGGAGCGGACATGCATGTGGAGAACGCGTCTGGAAACACAGCTCTTCATATCTGCGCTCTTTATAAACAGGAAAAGTGTGCCAGGGTGCTTTTGGTCCGCGGTGCAAGTAAAGACGTGAAGAACTATCGAGGACAAACGCCTTTTCAGgTGGCAATAATTGCTGGAAATTTTGAGCTTGCAGAGTTCATAAAGAACCACAAAGAAGCTGATATTGTGCCTTTCCGGGAGGCACCGGCAGGCACAGGACGGAGCAGGCCGTCGCAGCAATCGCCGCTGCAGCACCAGGGTAGGAGTACTCTTGCCGCCCCGCGAGTGCTGCTCCGATCCAACAGCGACAACAACCTGAACGTCAACAAGCTGTCGCTGGAGCGCTCACGCTCGCCCTCTCCTGCCGCTTCACCCCTGCGCAGCCTCTCGCCCCGCCACCCCCAGCAGATGCAGAACAGCCCAAATGGCACGGTGAAAACCATGGCCCTGGGCGGGCGCTCCGCCCGAAGCCGATCCCCTTCCCTGGGCCGGCTGGGGGAGGGAGACACGCGGAGACAGACCCCGCTACGCCACAGCAGTCCGCGTGCCAACAGAGATGCCTTTTCCGGCATAGAGACCCCCGGGTCCAAACGGAAGCTGTACAGCGCTGTGCCAGGAAGACACTACGTGGTGGTCAAATCATACCAACCGCAGGCCGAGGGAGAAATCGTTCTTTACAAGAACGACAGGGTCAAAGTTCTCAGTATTGGAGAAGGAGGATTCTGGGAAGGCAGTGCCCGAGGGAATGTAGGCTGGTTCCCTGCGGAATGTGTGGAAGAGATCCCGAGCAAACCCAACGAGGACAGGCCCTATGCCAGAGCGGACCGTTCAGAGAGAAGGAAGCTCTTTCGACACTACACTGTGGGATCTTATGACAGTTTTGATGCATCAAGCGACTGCGTTATCAACGAAAAGACTGTCGTGCTGCAGAAGAAGGATAACGAGGGATTCGGGTTCGTGTTGAGAGGGGCGAAAGCGGATACCCCCATTGAGGAGTTCACTCCCACTCCAGCCTTCCCTGCGTTACAGTATCTGGAGTCTGTGGATGAGGGAGGGGTGGCATGGAAAGCTGGTTTAAGAACAGGAGACTTCCTCATCGAGgTGAACCAGGATAACGTTGTCAAAGTGGGCCACAAACAAGTGGTCAACATGATTCGTCATGGTGGCAACCACTTAATCATCAAAGTGGTAACGGTCAGTCGAAATCTAGACCCTGACGACACGGCTCGAAAGAAAGCGCCACCGCCACCACGGAGGGCTCCCTCCACAGCCTTGTCCATGCGTTCAAAATCTATGACCTCAGAGCTAGAAGACCTAGATAAAGTGGATGAAGTCGTACCTCCTCAGAAACCCATATGGGACAACTCAAATGCAGAAGTGAGAGTGGCGACGGTCAAGCCACGTCCAACTAGCAAATGTTTTCCTGTCAGCCCTGAAATGAATTCTCTCTGCAATAGTCAGGATACAGCAGTAGATTCGTCACCACAGCCAGGGAGTCCTAGAGGCCCTTTTCTGGGTCTACCAAGGGGAACCATACGGCGGCAAACATCCATAGGAGTAACCGAAGAAGAGAAGCAGTTCCTTACTCCTCCAATGTTGAAATTTACAAGAAGCCTTTCGATGCCTGACACATCAGAGGATATTCCACCCCCACCAGCTATCTCCCCTCCATCTCCACCTCATAATAATGCTCCTGTCCCAGCTGGTCGAGGATACGGCACCATCAGAGCAGGTTTTACTTCACAGAGTCCTAATGCAAACAGCACAGCCCCGGAGAGAGGAGAAGGTGCTGGGTGGAGAGATCAGGGCAAGTATTACAGAGACAATCCCGAGCAGTATGATTCTGAGGGGTACAATCACAGCCCCACGGCCCAGCAGAGTCTTCATATGCGCCGTGCCCAAATCCCTGAGAACCCTTACTCAGATGTTGGTAAGATGGGTCAAGCTGGACTGTTTGTGCCCAACAAGCCTGCCAGAAGAAAGGGAATGCTTGTCAAACAGTCCAACGTAGAGGACAGTCCTGAGAAGACCTGCTCCATTCCTATTCCGACAATAATAATCAAAGAGCCCTCCACCAGCAGCAGCGGCAAAAGCAGTCAAGGAAGCAGCATGGAAATTGAGACGACCACTCCAGATCACCCAGGGCAGTTGCGTCCTGAAGATGGCCTAAATCCAGGCAGTCCATTTGCAGCTGCCATTGCTGGTGCTGTCAGAGACAGGGAAAAAAGGCTTGATTCTCATCGCAACTCACCATCTTTTAGGTCTACAGATGCTGGTGATGAAGATGTGGTTCCTACACCTACCCCAAGGCTTCGACACTCCAAGTCTATTGATGAGGGCATGTTTAGCAGCGATGAGCGGCTGCGTAGGCTCATGGCACCTCCCTCATCACTTCTTAGCATCCCTAGAGGTGGTGGCAATGTGACAGACTTCAACAGTCCCGAACCCACCATGGTAAGGGAACTGTTGAACACTCGTACAGGACACAGCCCAATCAGTCTGCCTGCTCATAAGACCTACAGCTCAGGAAGTGGGAATTACGTTCACCCAGTAACAGGCAAGCCACTTGACCCCAACTCACCATTAGCTTTAGCATTAGCTGCCAGAGACCGAGCCATGAGGGATCAATCACAGCCTCTTCCATTAAAAAGTGACCCATCCAAACTTGATCTCAATAAACCGCTTTTCATCGACACCAAGCTTAGACCAAATGTGGAGGTTGGCTTCTCAAGTACTGCTACCATGGGCCGTCCCCGTGGGGGCTTGAGGAGGCAGATGACTGAGTCCAAATATGAGACAGAATCCAAGTATCAGCTCGATTTGGGCAAGCCCGAAAAGAGGCCTGAGGAGAAGAAAAACATGCTGATTGACATTGTGGACACTTCTCAGCAGAAGTCAGCTGGTCTGCTGATGGTGCACACCACAGATGGGGCAAAATCTGAGGATAACAGCTTGTCAGAGGGCGAAAGGGACGAGGGAGTGAGTCCCGACAACACCCCTGGGGAGCTTCGCGACCCCAACCAGCCAGCTCCCACCAACCCCCCAGCCCCCAAGGCGCTATCAGCTGCTCCACATGGCAAGACCATTATAACTGTTAGCTCAGTGGATGAGCCTGTGAAGCTGCCCTTCGGCATCCCTCCACCGCCCTTGGCCTCTGTCGACATCGATGAAGAGTTTGTGTTTGCAGAACCCTTACCACCCCCACTGGAGTTTGCCAACAGTTTTGACATTCCTGAAGACCAGGCAGGAAGTATAGCTGAACTACTCAAACAGAAAGCAAATGGTACAAAAGGGCCTTCTCTTGCTCCCTACTATCCCGCGTTAGGTGGAGGGCATGCTGAAATCAAAAGATCAACAGTCCTCACAAATTGCACACCTCCCAGCTTCCCTCCTGGGCCTCTAGAGCCCTATGAACAAATCACTGACTCGGGCATTGAGGTAGACAGCCGGAGCAGTGGTGACCCCCAACTGGAGACCACCAGCACCATCTCTACTGTGTCCAGCATCTCCACCCTGTCTTCTGAAGGAGGTGAGACCCTGGATACGTGCACCGTCTATGCAGATGGACAAGCCTTTCTGGTGGACAGGTCTCAAATCCTGTCTAAACCAAAACCCAAACCTGCCATCAAGAGCAATGCACTTTACAAGGACTCTTTGCCTGAGGAGAACGTAGGCTCTTTCAGAATGCCCTCCTCTGTCCCACCTCCACCCCCTGGATCTATTCCACCAGAACCCTTGAAAACCCCAACGCAACGAACCTCAAAGCTGTGGGGTGACCCTCCGGAGATGAAAGGACCCCATGGGCCTGAAACCAATTCAGTTCTGCAGCATGTGAACAAGGACAAAGCACCAAAGCCAGGGGAAGCGTTAGACTCTCCGACTGGATCCAGGACTCACTTTGGAACAAGAAATCAGGATGGTGTATCCCTCATCTCAGGTACACAGCAAAACACCACCGTTACCTTCACTGCCCAGCCTGGCCCCAACGTGCCTGCCCCGTCACCGTGCCGACAGGCAGAGAGCCTGCCTCCCCACCACCACACCCCAAGCCCTATCATGTCCCCACCGGACTCTGGCCTCAGCTGTGCCTCTTCCCTCCCAACCTCGGCCACTTCCCCCACCATGACGGACGTCTTTGGCCTGCCCACACCGCCCCTCAGCCTGGGCACAGGGCGTAGCCGCTCCCCTTCCCCACTCACCCTCATCCAGGCTGCATCAAATAAGCCCtttgccaccaaacctgttctcTTGTGGAGCAAGCAGGATGTGGCCGACTGGCTCGAGAGCCTGAACCTGGGTGAGCACAGGGATGCCTTTATGGACAATGATATAGAGGGCAGCCACCTGCCAAACCTGCAAAAGGAGGATCTGATCGACTTGGGTGTGACTCGTGTGGGTCACAGAATGAACATCGAGCGGGCGCTTAAAGTCCTTTTGGACAGATGA

Function

symbol description
shank2b Predicted to enable ionotropic glutamate receptor binding activity and synaptic receptor adaptor activity. Predicted to be located in cytoplasm and synapse. Predicted to be active in dendritic spine and postsynaptic density. Predicted to colocalize with postsynaptic membrane. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human SHANK2 (SH3 and multiple ankyrin repeat domains 2).

GO:

id name namespace
GO:0051124 synaptic growth at neuromuscular junction biological_process
GO:0051968 positive regulation of synaptic transmission, glutamatergic biological_process
GO:2000463 positive regulation of excitatory postsynaptic potential biological_process
GO:0097107 postsynaptic density assembly biological_process
GO:0048854 brain morphogenesis biological_process
GO:0007610 behavior biological_process
GO:0060997 dendritic spine morphogenesis biological_process
GO:0060999 positive regulation of dendritic spine development biological_process
GO:2000311 regulation of AMPA receptor activity biological_process
GO:0007416 synapse assembly biological_process
GO:0060291 long-term synaptic potentiation biological_process
GO:0043005 neuron projection cellular_component
GO:0030425 dendrite cellular_component
GO:0045211 postsynaptic membrane cellular_component
GO:0044309 neuron spine cellular_component
GO:0008328 ionotropic glutamate receptor complex cellular_component
GO:0014069 postsynaptic density cellular_component
GO:0043197 dendritic spine cellular_component
GO:0035255 ionotropic glutamate receptor binding molecular_function
GO:0030159 signaling receptor complex adaptor activity molecular_function
GO:0030160 synaptic receptor adaptor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-061207-58 Predicted to enable ionotropic glutamate receptor binding activity and synaptic receptor adaptor activity. Predicted to be located in cytoplasm and synapse. Predicted to be active in dendritic spine and postsynaptic density. Predicted to colocalize with postsynaptic membrane. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human SHANK2 (SH3 and multiple ankyrin repeat domains 2).

Ensembl:

ensembl_id ENSDARG00000062325

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00047581 True 5411 mRNA 0.54 21 14165447 14366077

Neighbor

gene id symbol gene type direction distance location
XLOC_023961 CR382374.1 coding upstream 30743 14134590 ~ 14134704 (+)
XLOC_023959 actc1c coding upstream 39949 14087045 ~ 14125498 (+)
XLOC_023960 guca1g coding upstream 69136 14092871 ~ 14096311 (+)
XLOC_023958 chst1 coding upstream 144336 14017609 ~ 14021111 (+)
XLOC_023957 C25H11orf49 coding upstream 365594 13791627 ~ 13799853 (+)
XLOC_023963 ciapin1 coding downstream 32573 14398650 ~ 14406731 (+)
XLOC_023964 AL929309.1 coding downstream 65462 14431539 ~ 14433008 (+)
XLOC_023965 dbx1b coding downstream 141490 14507567 ~ 14510482 (+)
XLOC_023966 CR388067.1 coding downstream 318156 14684233 ~ 14684347 (+)
XLOC_023967 mpped2 coding downstream 328799 14694876 ~ 14739282 (+)
XLOC_023973 CR762411.1 misc downstream 851747 15217824 ~ 15218109 (+)
XLOC_023953 NA non-coding upstream 539724 13619831 ~ 13625723 (+)
XLOC_023952 NA non-coding upstream 602633 13558992 ~ 13562814 (+)
XLOC_023948 AL772241.1 non-coding upstream 883781 13281610 ~ 13281666 (+)
XLOC_023946 NA non-coding upstream 894911 13269659 ~ 13270536 (+)
XLOC_023969 NA non-coding downstream 565905 14931982 ~ 15034584 (+)
XLOC_023970 NA non-coding downstream 734461 15100538 ~ 15126304 (+)
XLOC_023971 AL929172.1 non-coding downstream 753520 15119597 ~ 15119730 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location