Bioproject ID: PRJNA380337

bioproject id PRJNA380337      to NCBI
key word Sex; ONCORHYNCHUS MYKISS; GENE-EXPRESSION; BALANCING SELECTION; ANTAGONISTIC GENES; WILD POPULATIONS; LINKAGE MAP; SALMON; RECOMBINATION; STEELHEAD; EVOLUTION
experiment type sex
publication Pearse DE, et al. "Sex-dependent dominance maintains migration supergene in rainbow trout", Nature Ecology & Evolution, 2019; 3:1731-+
description The study present a chromosome-anchored genome assembly for rainbow trout and characterize a 55-Mb double-inversion supergene that mediates sex-specific migratory tendency through sex-dependent dominance reversal, an alternative mechanism for resolving sexual conflict.
abstract Males and females often differ in their fitness optima for shared traits that have a shared genetic basis, leading to sexual conflict. Morphologically differentiated sex chromosomes can resolve this conflict and protect sexually antagonistic variation, but they accumulate deleterious mutations. However, how sexual conflict is resolved in species that lack differentiated sex chromosomes is largely unknown. Here we present a chromosome-anchored genome assembly for rainbow trout (Oncorhynchus mykiss) and characterize a 55-Mb double-inversion supergene that mediates sex-specific migratory tendency through sex-dependent dominance reversal, an alternative mechanism for resolving sexual conflict. The double inversion contains key photosensory, circadian rhythm, adiposity and sex-related genes and displays a latitudinal frequency cline, indicating environmentally dependent selection. Our results show sex-dependent dominance reversal across a large autosomal supergene, a mechanism for sexual conflict resolution capable of protecting sexually antagonistic variation while avoiding the homozygous lethality and deleterious mutations associated with typical heteromorphic sex chromosomes.

Sample Information

sample id sample name tissue strain treatment description
1. SRR5373280 Sample_26-RT-Sk-1 Skin nan Sample_26-RT-Sk-1 nan
2. SRR5373279 Sample_27-RT-M-1 Muscle nan Sample_27-RT-M-1 nan
3. SRR5373271 Sample_35-RT-E-1 Eye nan Sample_35-RT-E-1 nan
4. SRR5373274 Sample_32-RT-HK-1 Head kidney nan Sample_32-RT-HK-1 nan
5. SRR5373270 Sample_36-RT-B-1 Brain nan Sample_36-RT-B-1 nan
6. SRR5373273 Sample_33-RT-Sp-1 Spleen nan Sample_33-RT-Sp-1 nan
7. SRR5373277 Sample_29-RT-G-1 Gut nan Sample_29-RT-G-1 nan
8. SRR5373278 Sample_28-RT-H-1 Hearth nan Sample_28-RT-H-1 nan
9. SRR5373283 Sample_23-RT-L-1 Liver nan Sample_23-RT-L-1 nan
10. SRR5373282 Sample_24-24-RT-L-2 Liver nan Sample_24-24-RT-L-2 nan
11. SRR5373275 Sample_31-RT-K-1 Kidney nan Sample_31-RT-K-1 nan
12. SRR5373276 Sample_30-RT-PC-1 Pyloric caeca nan Sample_30-RT-PC-1 nan
13. SRR5373272 Sample_34-RT-Gi-1 Gill nan Sample_34-RT-Gi-1 nan
14. SRR5373281 Sample_25-RT-L-3 Liver nan Sample_25-RT-L-3 nan