XLOC_010172 (nek11)



Basic Information


Item Value
gene id XLOC_010172
gene name nek11
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 41171949 ~ 41296829 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00020162
gagctcagctctgcccaagtcaagtggctctgcagtgagcaccacttggcAAAATTTAGCTTACAGTCAGCAGTGCACATTAGCGCCATCTTAAGGAGAATAGTGCGACTGCACAGTTCCCATAACAACAACGTAACACGGGAAGTTGAGCACATGTGGTCAAGCAAACTTCCGACGCACAGCTGACTGCGTTAAATTCCCGGCTTAAAATGCCCAGATTTCGTGAGCGTCCAGGCCAAACAAACTGTCATCCAGAATCAGAAACATCTCCTGATCTGTGCAGCCTGATAGCGAACAGATACATCATCCAGCAGAGACTCGGGAAGGGAAGCTTCGGCACTGTGTATCTTGTTAAAGACACAAAGGCAGTGGCGGAGGAGAGACTGAAGGTTCTGAAGGAGATTCCTGTTGGAGATCTGAAACCCAATGAAACGGTCCATGCCACTCAAGAGGCACAGCTTCTCTCTCAGCTCAGCCACCCAGCCATCCTTAAATTCTACAGCAGCTTCCTGGAGAGAGACGCCTTCTGTATCATCACTGAGTTTTGTGAGGACAAAGATCTGGACTGTAAGCTGGAGGAGCTAAAACACACAGGCAAGACTTTGTCAGAGCCTCAGGTCTGCGAATGGCTTTGTCAGCTTCTGTTGGGAGTACATTACATACATCAGAGGAGAATACTTCACAGAGATCTAAAGgccaaaaatatatttctgagGAAAAACATTGTTAAGATAGGTGACTTTGGTGTGTCCTGTTTTCTAATGGGATCATGTGACCTGGCGACTACCTTCACTGGGACCCCATACTACATGAGCCCTGAAGCCCTGAGCCACAAAGGATACGACTCTAAATCGGACATATGGTCTTTAGGCTGTATCCTCTATGAGATGTGCTGTTTGGCTCACGCTTTCGAGGCGCAGAACTTCTTGGCCGTGGTGCTGAGGATTGTAGAGGGACCCACTCCATCCCTGCCAGAAACATACTCACGGCAGCTCAACTCCCTAATGCAGAGtaTGTTAGAAAAGGATTCTTCTCACAGGATCTCGGCGGCAGATGCTCTGAGAAACAGGTTCATTGAGGAAAGCTTGCAGAGTATGAAACACAAGTTCTCCATCCTGTCACTGAGAGACAAGTCGATTGGGGGAGAGAGAGATGCATCGCAGATCCTGAGAGCACTGCAGAAGAAGGTGCATCTGCAGACGCTTCAGGACAGATCAGAGGTGCAGAAAATGAGCCCCAGGGAACGAATGCGGCTCCGGAAGCTCCAGGCAGCGGATGAGAAGGCAAGAAAGCTGAAACAAATTGTGGAAGAAAAATATCAAGAAAATCATCTCCGCATGCAAGAGTACAAGTCCAAGAATTTTCATAAAATCAGTGTGGATTTTTTGAAGGTGCAACCTGAAGAAGCAGTTAACCAGACTCAAGTGATTCAGAGTGAGTCACCGAAGGAAAACTCTGAAATGACTGGAAACGTTTCTCATCTCACTGATAAGATGTGCACGACTGTGTCAAAAGAGCATGCAATCCCAGAGGATCCTCAGGCGGCAGAAGCATTTTACTTTGTGGATGAATTCGAGTCATGCTCGGAGGAAGATTCAGATGGAGAGGAGGACCCAGAGGATAATCTCCCTACAGACCCGTCCTGTCAGACATGTGGACAGgACGGTGACCTGGAGGCCTTGATCAGACACATGGAGAACGTTCTGGTTGGAGATTCAGATGGAGCTGAAACAGAGAATGAGAAGCCTCAGCTGGGTTTTCTGGGAGTCGGTAGCATCAATATGTCCATGGCTGAGGGCAGAATCCAGCGGATGAGAGAGTCTGTGTGTCGGAGGCTGGGTGAGGAGGTGTTCCTGAAGGTCTATGATTATCTGAAGCAGGCCAGACAGAAGCAGGAGAGCGAGGAGAGCATTAGACAGACTCTGATAGAGCTGGTGGAGAAACCCAGCGACTGCTTTGAAGTAGATCAACTTCTTTATTATGAAGAGATTCTTCTGGCAGCGCAGGAAAACACTGTAAGATAA
>TCONS_00020163
ATGCTGGGTGAGGAGGTGTTCCTGAAGGTCTATGATTATCTGAAGCAGGCCAGACAGAAGCAGGAGAGCGAGGAGAGCATTAGACAGACTCTGATAGAGCTGGTGGAGAAACCCAGCGACTGCTTTGAAGTAGATCAACTTCTTTATTATGAAGAGATTCTTCTGttaaacgtttttatttctgtgatttcTATGGGATAA

Function


symbol description
nek11 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in chromosome segregation; mitotic intra-S DNA damage checkpoint signaling; and regulation of mitotic cell cycle phase transition. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in centrosome; cytoplasm; and nucleoplasm. Orthologous to human NEK11 (NIMA related kinase 11).

GO:

id name namespace
GO:0031573 intra-S DNA damage checkpoint biological_process
GO:0006468 protein phosphorylation biological_process
GO:0007059 chromosome segregation biological_process
GO:1901990 regulation of mitotic cell cycle phase transition biological_process
GO:0005813 centrosome cellular_component
GO:0005634 nucleus cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
ko01001 Protein kinases
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-100922-73 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in chromosome segregation; mitotic intra-S DNA damage checkpoint signaling; and regulation of mitotic cell cycle phase transition. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in centrosome; cytoplasm; and nucleoplasm. Orthologous to human NEK11 (NIMA related kinase 11).

Ensembl:

ensembl_id ENSDARG00000087564

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00020162 False 2024 mRNA 0.48 16 41171949 41293417
TCONS_00020163 True 201 mRNA 0.43 3 41293168 41296829

Neighbor


gene id symbol gene type direction distance location
XLOC_010171 sc:d156 coding upstream 2360 41162854 ~ 41169589 (+)
XLOC_010170 NA coding upstream 23786 41142659 ~ 41148163 (+)
XLOC_010169 si:ch211-53m15.2 coding upstream 35810 41135018 ~ 41136139 (+)
XLOC_010168 NA coding upstream 42629 41129064 ~ 41129320 (+)
XLOC_010167 scap coding upstream 68167 41060161 ~ 41103782 (+)
XLOC_010173 BX005012.4 coding downstream 168682 41465511 ~ 41473318 (+)
XLOC_010174 si:dkey-11p23.7 coding downstream 220359 41517188 ~ 41521289 (+)
XLOC_010175 BX005012.2 coding downstream 249934 41546763 ~ 41548437 (+)
XLOC_010176 aste1a coding downstream 273824 41570653 ~ 41579815 (+)
XLOC_010177 ubxn11 coding downstream 371645 41668474 ~ 41681746 (+)
XLOC_010166 NA non-coding upstream 117297 41036647 ~ 41054652 (+)
XLOC_010163 NA non-coding upstream 226192 40941737 ~ 40945757 (+)
XLOC_010162 NA non-coding upstream 278431 40873241 ~ 40893518 (+)
XLOC_010183 BX649388.2 non-coding downstream 769753 42066582 ~ 42073705 (+)
XLOC_010184 NA non-coding downstream 793477 42090306 ~ 42096260 (+)
XLOC_010186 NA non-coding downstream 1040416 42337245 ~ 42337549 (+)

Expression



Co-expression Network