CI01000063_00864936_00881531 (LIPA, LIPF)



Basic Information


Item Value
gene id CI01000063_00864936_00881531
gene name LIPA, LIPF
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information


Item Value
chromosome id CI01000063
NCBI id null
chromosome length 7808773
location 864319 ~ 881531 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence


>CI01000063_00864936_00881531.mRNA
AAGTACACTAAATATTTCTTGTTTCCAAGACTCACGAAAAGAGGACAAACACCCCATCACAGACAGAGGAGTGAGATCATCAGACACTGGGGCTACCCAGCTGAAGAATTTGAAGTGGTCACCGAGGATGGGTACATACTGAGCGTCAACCGAATCCCACATGGGGTCAAAAACAAGGATGGACAAGAAGCCAAGCCAGTGGTGTTCCTCCAACATGGTCTCCTCGCTGCTGGAAGTAACTGGGTTACAAACCTGCCCAACAACAGCCTGGGTTTCCTCCTAGCCGATGCTGGATTTGACGTGTGGATAGGCAACAGTCGTGGGAACACCTGGTCCAGAAAACATGTCAGCCTTGACCCTAAACAGAAAGAATACTGGGAGTTCAGGTACAAGACATTCATGGCTTTCTCTACGATGCCGGAGCTGGCAAGCAAAATCAAGATGTTCTTTGCCCTGGCTCCTGTCGCCACAGTGGCGTTGACTAAAAGCCCCATGACCAAATTGTCTGTTATTCCAGAGTTTCTCATTTGGGATCTCTTCGGAAGAAAAGACTTCCTGCCTCAGAATGACTTGATTAAGTTTTTTGCCACTGAATTCTGCAGCAAAAAGCCTTTGAGTGTGCTGTGTGGAAACATCTTCTTTCTCCTCTGTGGTTTTGATGAAAAGAACCTGAACATGACCAGAACACCTGTGTACACGACACACTGCCCAGCAGGAACCTCAGTCCAGAACATGGTTCATTGGGCTCAGGCTGTGAAATCCAGTAAGCTTATGGCATATGATTATGGAAAAGCTGGAAATATGGCACATTATAATCAGTCAACCCCTCCTCTGTACAATGTGAAGGACATGACTGTACCTACAGCTTTGTGGTCTGGTGGACAGGACACTCTGGCAGATCCTCAGGATGTGGCTCTACTGCTCACACAGATACCTAAATTGAAATACCACCGCAACATCGAGCACTGGGAACACCTGGATTTCATCTGGGGCTTGGACGCCCCACAAGAGATGTACAGCAAAATGATCGAAATTATGAGGGAGTATGTATGAAGAGACATTTTGATTGAGCAGCATGTTTTATCAGCAATTTGTTTTTACCATGCTTTGAGCTTAAAGCAATAGTTCACATCAGTAAGCAAACAATTGATGCGACCCCATTGACTTCCATAGTATTTTTTTCCATACTATGAAAGTCAATGGGGTCCACCAACTGTTTGCTTACCATAGTTCTTCAAGATACCTTCTTTTGTGTTCAGCAGAAGAAAGAAATTCATACAGGTTTCAAACAACTTGAGGGTGAATAAATGATGGCAGAATTTATTTTTGGGTGAACTATCCCTTTAAGCTAATGCTTTTCTACCTCTGTTTATTCATGCTTTAAGCAGATGAACCATTTGTTTGAGGTGCTGGCAACCCAACCTGCAATCACCAATGTATATTTGAAATTACAAACTGATTAATGCCTTCAGCATCACCTAAAGATTGAGTTTTACACTCATAATCAGGTGTTGCCTTTTAATGTATTTTAAAGGACATGCACTTGTTTAATGTGTTTTTCACTTTTTCATTTTTTGCTTTTACTAACCACTACAACTTACCATACTGTAGCATTTCATGACCTGTCTTATGCAATGGACTTTGTAAATCATGACTTGAAACCCAATAAA

Function


symbol description
lipf Predicted to enable hydrolase activity, acting on ester bonds. Acts upstream of or within response to hypoxia. Is expressed in gill. Human ortholog(s) of this gene implicated in Wolman disease; cholesterol ester storage disease; and lysosomal and lipase deficiency. Orthologous to human LIPA (lipase A, lysosomal acid type) and LIPF (lipase F, gastric type).
lipa Enables sterol esterase activity. Predicted to be involved in sterol metabolic process. Predicted to act upstream of or within several processes, including homeostasis of number of cells within a tissue; lung development; and tissue remodeling. Located in cytosol; fibrillar center; and nucleoplasm. Implicated in Wolman disease; cholesterol ester storage disease; and lysosomal and lipase deficiency.

GO:

id name namespace
GO:0016787 hydrolase activity molecular_function

KEGG:

id description
K01052 LIPA; lysosomal acid lipase/cholesteryl ester hydrolase

RNA


RNA id representative length rna type GC content exon number start site end site
CI01000063_00864936_00881531.mRNA True 1670 mRNA 0.43 8 864319 881531

Neighbor


gene id symbol gene type direction distance location
CI01000063_00846790_00858096 STAMBPL1 coding downstream 4941 846622 ~ 859378 (-)
CI01000063_00808299_00809636 NA coding downstream 54683 808060 ~ 809636 (-)
CI01000063_00805911_00806593 NA coding downstream 57687 805911 ~ 806632 (-)
CI01000063_00792983_00795702 NA coding downstream 65105 792436 ~ 799214 (-)
CI01000063_00732118_00733108 NA coding downstream 130314 731590 ~ 734005 (-)
CI01000063_00985283_00999270 PTENB, PTEN coding upstream 102990 984521 ~ 999270 (-)
CI01000063_01015926_01020021 PAPSS2A, PAPSS2B, PAPSS2, PAPS2 coding upstream 134395 1015926 ~ 1020021 (-)
CI01000063_01023917_01026650 MINPP1B coding upstream 142122 1023653 ~ 1027279 (-)
CI01000063_01029007_01032212 NA coding upstream 147451 1028982 ~ 1032212 (-)
CI01000063_01070457_01077403 USP42 coding upstream 188692 1070223 ~ 1077862 (-)
G262862 NA non-coding downstream 21211 839451 ~ 843108 (-)
G262922 NA non-coding downstream 29974 834059 ~ 834345 (-)
G262913 NA non-coding downstream 38886 825209 ~ 825433 (-)
G262854 NA non-coding downstream 153756 710089 ~ 710563 (-)
G262853 NA non-coding downstream 154707 709256 ~ 709612 (-)
G262959 NA non-coding upstream 63616 945147 ~ 945562 (-)
G262960 NA non-coding upstream 64493 946024 ~ 946283 (-)
G262964 NA non-coding upstream 66421 947952 ~ 948214 (-)
G262965 NA non-coding upstream 67057 948588 ~ 949001 (-)
G262967 NA non-coding upstream 68646 950177 ~ 950529 (-)
CI01000063_01669384_01670016 HBAE1 other upstream 787880 1669317 ~ 1672019 (-)
CI01000063_02177769_02178239 NA other upstream 1294908 2177747 ~ 2178395 (-)
CI01000063_02326799_02327290 CBY1 other upstream 1443581 2326741 ~ 2327309 (-)
CI01000063_02725759_02726399 NA other upstream 1844228 2725759 ~ 2726535 (-)
G265567 NA other upstream 4280963 5183279 ~ 5183287 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_005280 lipf coding NC_007123.7 CM002896.2 17158642 ~ 17201028 (-)