XLOC_010360 (slc6a3)



Basic Information


Item Value
gene id XLOC_010360
gene name slc6a3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 248239 ~ 263658 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00020402
ATGCCCATGCTGAGAGGCAGACCGGcggtcacacacacacgcacacgcacacacacacacatgtcctCCGTCAGCGGCTCCAGCAGCGCCGCCGGGCCCCGAGAGGTGGAGCTGGTGCTGGTGAAGGAGCAGAATGGGGTTCAGTTCACCTCCTCCAGCCTGCGGAGCCCCGGtgcgcactcacacacacacacccactctcACACACACCCGTCCGGACAGCAGCGTGAGACCTGGGGCAAGAAGATCGACTTTCTGCTGTCCGTCATCGGCTTCGCTGTGGATCTGGCCAACGTCTGGAGGTTCCCATACCTGTGCTACAAGAACGGCGGAggagcgtTCCTGGTGCCGTATCTCTTCTTCATGGTGATCGCCGGGATGCCGCTCTTCTACATGGAGCTGGCGCTGGGTCAGTATAACCGTGAAGGAGCCGCCGGCGTCTGGAAGATCTGCCCCATATTCAAAGGCGTGGGCTTCACGGTGATCCTGATCTCGCTGTATGTGGGCTTCTACTACAACGTGATCATCGCCTGGGCTCTGTTTTACCTGTTCTCCTCCTTCTCCGGGGAGCTGCCCTGGATCCACTGCAACAACACCTGGAACAGCCCCAACTGCTCCGACCTCAACGCCACGCTGCTCAACGACACGTACAAGACCACGCCCGCGCTCGAGTACTTCGAgcgGGGTGTTCTGCATGTTCATGAAAGCTCTGGTATTGATGATCTGGGTGCGCCGCGCTGGCAGCTGACCGCCTGTCTGGCCGTGGTCATCGTGGTCCTCTACTTCAGCCTCTGGAAAGGAGTGAAGACGTCTGGGAAGgtggtGTGGATCACTGCCACGATGCCGTATGTGGTCCTGACCGTGCTGCTCCTGCGTGGCGTCACTCTGCCTGGAGCCATCGACGGCATTAAAGCTTACCTGAGTGTGGACTTCCTGCGCCTGTATGATgctcaggtacatgtgcacacttgtacatgtttgtgtgtgtgcttatGTATCGGTGTCTGTttgcttgtgtgtgcatgttcatatgtatTCTTCagtaatgcgtgtttcagagacgCCATCATCACCAGCTCCATCAACTCTCTGACCAGCTTCTTCTCCGGCTTCGTCATCTTCTCCTTCCTGGGATACATGTCACAGAAACACAACGTGGCCCTGGATAAAGTGGCCACTGacgGTCCCGGCCTGGTGTTCATCATTTACCCAGAAGCCATTGCGACGCTGCCCGGCTCTTCAGTGTGGGCCGTCATCTTCTTCATCATGTTGCTGACTTTAGGAATCGACAGCGCTATGGGAGGGATGGAGTCTGTGATCACGGGACTCATCGACGAGTTCAAGTTCCTGCACAAACATCGAGAGCTCTTCACACTCTTCATCGTGGTGTCCACCTTCCTCATCTCGCTCATCTGCGTCACCAACGGTGGAATCTATGTGTTTACGCTGTTGGACCACTTCGCTGCGGGGACGTCAATTCTCTTTGGAGTACTAATTGAGGCCATCGGCATCGCCTGGTTTTACGgagTGGATCGCTTCAGTGATGATATCGAGGAGATGATCGGTCAGAGACCAGGCCTGTACTGGAGACTGTGCTGGAAGTTTGTGAGCCCGTGTTTCCTCCTGTTCATGGTTGTGATCAGCTTCGCCACCTTCAATCCTCCCAAGTACGGCTCCTATTATTTCCCCACGTGGGCGACGATGGTGGGCTGGTGTTTGTCCATCTCCTCTATGATCATGGTGCCGCTCTACGCCATCTACAAGTTCTGCTCGCTGCCCGGAAGCTTCTGTGACaaacTGGCGTACGCCATCACTCCTGAGACTGACCATCACCTGGTGGAGCGCGGTGAGGTGCGGCAGTTCACGCTCCATCACTGGCTGGTGGTTTGA

Function


symbol description
slc6a3 Predicted to enable symporter activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including dopaminergic neurons; forebrain; male organism; medulla oblongata; and retina. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; nicotine dependence; and obesity. Orthologous to human SLC6A3 (solute carrier family 6 member 3).

GO:

id name namespace
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0015293 symporter activity molecular_function
GO:0005328 neurotransmitter molecular_function

KEGG:

id description
ko04728 Dopaminergic synapse
ko04721 Synaptic vesicle cycle
ko05012 Parkinson disease
ko05022 Pathways of neurodegeneration - multiple diseases
ko05030 Cocaine addiction
ko05031 Amphetamine addiction
ko05034 Alcoholism
ko02000 Transporters

ZFIN:

id description
ZDB-GENE-010316-1 Predicted to enable symporter activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including dopaminergic neurons; forebrain; male organism; medulla oblongata; and retina. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; nicotine dependence; and obesity. Orthologous to human SLC6A3 (solute carrier family 6 member 3).

Ensembl:

ensembl_id ENSDARG00000004219

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00020402 True 1890 mRNA 0.56 17 248239 263658

Neighbor


gene id symbol gene type direction distance location
XLOC_010359 NA coding downstream 8966 227820 ~ 239273 (-)
XLOC_010358 NA coding downstream 41980 204125 ~ 206259 (-)
XLOC_010357 NA coding downstream 70376 173564 ~ 177863 (-)
XLOC_010356 NA coding downstream 180532 66537 ~ 67707 (-)
XLOC_010361 LO017917.1 coding upstream 14131 277789 ~ 280835 (-)
XLOC_010362 NA coding upstream 39097 302755 ~ 313553 (-)
XLOC_010363 NA coding upstream 82605 346263 ~ 353780 (-)
XLOC_010364 NA coding upstream 91188 354846 ~ 367144 (-)
XLOC_010365 irx4a coding upstream 115108 378766 ~ 383664 (-)
XLOC_010626 CR392024.2 misc upstream 20631454 20895112 ~ 20895175 (-)
XLOC_010366 NA non-coding upstream 288024 551682 ~ 552627 (-)
XLOC_010368 NA non-coding upstream 940484 1204142 ~ 1218570 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000111_01622899_01645714 NA coding CI01000111 null 1622899 ~ 1645714 (-)