XLOC_010367 (irx2a)



Basic Information


Item Value
gene id XLOC_010367
gene name irx2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 555746 ~ 563732 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00020407
AGACATTTTGAACTCACAAAAAGAATAGCTATTATAAATGTGCATAATTGTTTTTAGACATATATCGTGTGCAATATGTTTTGGAAATGTTTGCATTTGTTTCGGAAAACTTTCACTGACAATTACAAATGCAATCTTAGTGCACACTTAGTTGTCTGCATTGTGCACTACATAGTTGTGATTAAATACAGGCCAACCTGGCGGGGTTTTTACAACaacataagagagagagagagagagagagagataaatgaCAAATGGGAAAGTGTCATCGTGTCATCCGTCAAGCAaatcaaaaagaaagaaaaacgcaGTAGATAAACGCCGGCGAGGACACATGCACGCACGGGCTGCTTTCTGTGCGGGTTTTGTTCCGGAATTGCATTTCACAGCGCGCGCGcacgagagggagagagagagagggggcgGGGATGGAATATTCAGATGAGCCGTGATTGACAGCTCCCGTTTCTCCAATGCTCTCAGAAACTCGCCTGCTCCTTCCAGCAACTCTTCACTCTCCACTCCCGAGCACTACAAACAAACGGACGCTAGGGGATCTCCATGACGGCTCTCTGCTGAACGCTCCTCTCGTGcgcgtttatttattttattttattagttcgCGTCCGGTGCGTCAATGCGCTGATTCCATCGATCAGCCCGATTTCGCGTTGTGGAGAGAAGCTGAGTAATAATGTCCTATCCTCAGGGTTACCTCTACCAGCCCCCGGGCTCTCTGGCGCTTTACTCGTGTCCGCTGGCCGCCCCGAGGAGCGAGGATTTGGCCCGGTCATCCTCCGGTTCCGCGTTCAGCCCGTACCCCGGGTCGGCGGCGTTCACAGCCTCCGCCAACGGATTCTCCAGCCCGCTGCCCTACTCCACAGATCCGGCCACGGGATTCCCGTCCTACATGGGCTCTCCGTATGACGCGCACACTACGGGAATGGCAGGAGCCATAAGTTATCACCCGTACGGGAGTCCCGGTTACCCGTACCAGCTCAACGATCCCGCTTACCGGAAAAACGCCACTCGGGACGCAACAGCGACGTTAAAAGCGTGGCTGCAGGAGCACAGGAAAAACCCCTATCCCACTAAAGGAGAGAAGATCATGCTGGCCATCATCACCAAAATGACCCTCACGCAAGTGTCCACCTGGTTCGCCAATGCACGACGGAGACTCAAGAAGGAGAACAAGATGACCTGGGCACCGCGGAATAAAAGTGAAGACGAAGACGAAGATGACGGAGATGGAGAGAGAAAAGACGAGCGCACGGATAAAAACATGGACAACAGCGAAGCGTCAGCTGAGGACGAAGGCATCAGTTTGCACGTCGATGCCCTGACAGACCACTCGTGCTCGGTGGAGTCGGACGGGGAGAAGGTCACGTGTCGGACCGGAGACCTTGTTTGCGATTCTGGAGCTGAAATCCAGGACAAATGCGAGGCGACGGATCTCGGGGAGGAAAGGCAGCGAGGCGCGTCACCCAAACCGGTGACCTCTTCTCCTCTGACCGGGGTGGAGGCGCCTCTATTGACCCATCATCACCGGGAGAACAGCACCAACAAAACATGCCTGGACGGTCAAAACCAAACCGTCAAGCCTAAGCTGTGGTCATTAGCAGAGATCGCCACTTCGGACCCCAAGCAGCAGAACTGTCCCCCGGGTGTCGGCCTTCTGACCTCCAGCGCGCCCGGCGCGTCCCCGGCGGGCGCGGTTTACCCCGCCACCTCCATACTAGGAAGACCTCTTTATTACACTTCTCCGTTTTATAGTAATTACACAAACTATGGCAACTTCAGCCCGCTTCAGGGCCAGGGGATACTGCGCTACAACTCCGCCGCAGAGGGACTCCTTCATAAACAGACTGGAGAGCCGCTAATAAAGACTAATCCAAACCAGACTGAAGCTCACTTCAGGGCCTCCAATGCAGAATCCAAAAAAGGTGCGTAGGCTGTTAATCTCTGAcagctatattatattatattatattatattatattatattatattatattatattatattatattattagaccCTTTTTACAGAATCGGTCgcggttttaaaatgatttcaacGCAAATTGTGTATGCATAAACTGCTGGATTGTTAATTTCAATTCATTCATAACCAGATTGATTGAGTTTGTCTTATATTCTAccttaaattgtgtttaaaaaacttATAAATGTTAACCAGATTCCGCAGTTCCCTCGTTTATATTGTTGTTTGCACTTGACATGCATTTCCCCTACTGTTTATTCCCTCAATCGATCGCGGAATACGAAGTAGCCCATTTAAGCTGTCAAAACGATTCCCTTCACTAAATTGGGTGTGTATTTCCTGCAGACCCCAGCGAGGTTTTCACAGTAAGATCCCAATCTTACCTGTCGAGTTAAGACGAGGAAGATCTTCCAAGTAAGTCGCTAATTTGAGCATTTCAGtgctgattattattattctgtatgctTCTGAAGGCCACGTCCTCATATTTGACACCTGTCAACATACGCTATAAATAATGCTGAGATGTTTTATCCAAatattggatttattttttatttttttgtaattaaatttattttacgaTTTTGCTTTTTGCAAATTTGTCCTTATCTGACCCAGCGTTGGGTTACAATAACCCAGCATATTTAGAGTGCATGAATATGACACTTCCCATCGACTCAAAGGTTGCTTCATGAAGTGTGTGTATTTCTAAATGTCATGctgtagttttatttcattcACTTTCTCTGGAAAAATCGACTGATGTAGGTTTTGTTTCCTTGGTTCACAGGTAGGTGTCACAATTGCTTTGAACAAAGCGAACAAGCCATcaccccttctctctctctctctctctctctctctctctctctctctccctctctctctctctctctctctctctctctctctctctctctctctccccaagCTGTTTTAAACTAACATTTGCTCCTTATACGCGGATCCTCTTTTGTGTGCCACTGTACACCCACGGACTACAGAGCACCTGCCtatacaataacaacaacaacactgcgATTGCGGGACAGAAACGCAAAGACAAGACAGGACAAGAGAAAGAAGAGCGAGTTTATAAGGCACAATAGCCAGTCTGCTTTGGACGAACTGCTGATTTATTGATGAAGTACTTTATCCCAACACATGTGACTTTTCCATGAGGAAACTTATTTCTCAGGATCCTAATAGTAGCTTCATTGCCACCAGTTGTAAACACGCGTgggacatttattattattaattattattattatagacctCCTATGAGACTTTATATGTGCTATAGAGGTGTGAAGTGTAAATGAGATCTCGGGACTGGTATAAACTTGACTAAGAGTGGAAtacatttgatatttatttttgtaatgccTATAATTTATGCAAGTTGTATTGCAATGGTTGCTGAacattgttttgtaaataaattatgatgggtttttattttaaaaaagccgAAGTTACACAATGTTGTTAACAAGGAGACTTTTACTAATTTATATCTCTCGTTGTAAATAAAAATGCGCTAGTCTGCACTGGCACAACACTGTCTGGGGACCGGCCTGCTTTTCTTTTGAGGAAAcgtctcattattattattttttaatcgtAGTTGTTTGCTTGTCGTATACATTTAGTCATGCCATACAAATTAGGTGGCGAGTTTAACACCGAAATCGTCCcaattttaattatttgcatTAAATTCCCGCTGTCTCTGAATGCAAAGCGTGAATGTTTGATGGCAGTGAATAATAGAAGCTGCTTATAATCCCGGCCTTCATCTATTTTTCAGCATGATGAATACAGGGCTGGAAAGGAAGCGTTATGAGCTCCCGGCGGGGTTTTAAGATGGTCAGTCGGGCTTCATTATAGACCGATATTGAACGATCCATAAAATCGTGTCTAAACATCTGCCAGCTCCGATGGGGCCCGTGTGATGATGGCAATGACGTCTCTCTTATACGGGGCCCCCGTTAAAATTTTAAAGGCCTTTTTTAAAACAGATTAGCCTCAGTGTGTGTTAACCTCAACAGCAGCTCAATGCAGCAATTATTATCTACACATTAGCCCTCGCCCAATTAAGAAAATAGGcgtatttttgtaattattattattattattattattattattattattattattattatattaacactgtacaataaggtataatatttttttattaacttgaacaAACAACGAgcagtacatttattacagtatttgttcgtgtcaataaattaaaataaaattgttgagTTGTGCATTAGCATGCTAACAAGCATGCATTTGGATTTTCGGTAACACTACAATAAGGTCGTATTAtgctagttaatgcattaactaactaacaaacaattgaaaaatacattcataacaatatttctttattttagttaatgaaaaaaaagtttaatgttaactcacggtgcattaactaattctAACACGCATGCATTTGGATATTAATAGTGCATTAGTAATTTTTGAACTGTGATTAATCAATGATCTACAAGTATTGCTCTTAATTATTTCACAGTAAGCACATCAACTAATAAAATCGtataatataaagtgtgaccttaataGTAGGATATAATAACAACAGCAGTTATGAAATCAATATTAATAGGTACATAAAAATAGTACCATAATAAATAgagctgattatgtgctttaatGGTTTTCAACGATTAATAATTAAATTGCACACATCAGTGAGTGTTTTCATCTTCGTAATAAGTCACTCGCGTTTAATGCTGCGTGTTTTACACAGCACTGAATTTGACTGAATGTCACTTTCATCGATAGTTCAACGCATGATTTAGTCATTTGAAGTGCTTTTCGCTTGTGCATATAAGCCTAGGCTCGATTATTAAAGGTGAATTATTGAAATTCAGACTTTAATCTCAGGTGGGATCCCGGGGGATCGACCACTGTTGTCAAAATGGCACCACAGGCGGTTTCCATTCATACTCCCTTCAAATGTCAACATTTGTTCTCAATAAAAAGAGTTATTGTTTCTGTAAAACAGCCTTTGAAAACATCAAAGAAGTTCAGGCACCTCTGTTTGATTGGGATCAGGTAAAGGTGAGCTGAAACAGCGCCGGTTATTGAGGATTTGCGGCATGAGGATTTTGCTATTTAATACGTACACTAAAGCAATATTTTAGTCTACGAATTCTGAATGAGATATGTGGATAATTAAGCACAGGTTTCCCGATAATTAAAAGTTAGTTTAATTTCTGCGATGGTGACATTTAAGGCTGACACGTTTAAGAGTTGatattaaattgtttacattGATCATAGCGTAGCCATTGGATTGTTTGTTAGTAATAAACTGTGTTGGGTTCAAATAAGGTTATATATTACAATCTTAAGCCTATCCCAATCTtttaaaaaaggaataaataGCATAGCATGCTTTCATATTAATAAAGTGTGAGTATAGTCTATTTAAAAAGTAGTAAAATAGGcttactttgtaatatttaaacTGCTAATGAGATACTGAATATATGTAATAGTTGTTTTCTAATTTGTGTTTGTGATTAGCTGAGTGAATCCAACTGAAGAGGGCAAAAGCACATTATTGAGACACTTTCTGAACGCGGAGCCTCTAATGGCCTCCTCTATTCTGCACCGTTTATCTTTACAACTTTAATCTACCATTAGAGTCAAGCCGTAAATAACATTTCGGGTCAGGAAAGGAGAGAAAAAGTATTAACAAATCGAGTGCATGTGGGTTTAATGAGATACATCAAAGTCTGCGAGGCTCTAAAGTGAGTCCCGGGTCGGTTCTTCCATAAAGGTGTCAGAGATGATGTCCTCCCATTAGCCTGATCAAGGCAGCAGAGGGAGAGTTTGTCCACACCGGACTCTAAATAAGACCATTACAGGCCTCCAGTTCCTGCCAAATACAGTAGATCTCACTTAACAGCCTATTTGCTTATTTCTCTCTGTTTGTtgcatgtcatatttaatttatcCCCCGAAATGTTTCACTTCTGGTTGTTAACACCTTTAGTCAGCTTTAAGAATAAAACACGCTTTTGGGAAGGATTTAACGCACTTAACGCTGAGGAGGATTTTCCCTGGGTGCATAtctatcatgtgtgtgtgtgttgctttatAGAAAAAGCATTTCCATGAATGATCAAGGAGGCTTGAGTTAACCTAAATAGTGgcagaatgacaaagaaagcagcgcgagaagaaagaaaaatattgGTGGAGAGTTTAATGAAGGGTGGGGATGGCTGTGTAAGATGAGGACAGGCCAAGGGAATgctattttttaatatgtcactGTTTGCACTAATAAGAGAGGTAACCGAACACCTTTAAATATCCTCTCTCACACGCCCGACTCGTTTTTAATTAAAAGCTACTTGTACAAAGGTTCAAATACAAATATGATTACAAGCACTTAAAATAACAAGAACCAATAAGTTCAAGTTGGTACACAAttgcacattttac
>TCONS_00020408
CTCCTTCCAGCAACTCTTCACTCTCCACTCCCGAGCACTACAAACAAACGGACGCTAGGGGATCTCCATGACGGCTCTCTGCTGAACGCTCCTCTCGTGcgcgtttatttattttattttattagttcgCGTCCGGTGCGTCAATGCGCTGATTCCATCGATCAGCCCGATTTCGCGTTGTGGAGAGAAGCTGAGTAATAATGTCCTATCCTCAGGGTTACCTCTACCAGCCCCCGGGCTCTCTGGCGCTTTACTCGTGTCCGCTGGCCGCCCCGAGGAGCGAGGATTTGGCCCGGTCATCCTCCGGTTCCGCGTTCAGCCCGTACCCCGGGTCGGCGGCGTTCACAGCCTCCGCCAACGGATTCTCCAGCCCGCTGCCCTACTCCACAGATCCGGCCACGGGATTCCCGTCCTACATGGGCTCTCCGTATGACGCGCACACTACGGGAATGGCAGGAGCCATAAGTTATCACCCGTACGGGAGTCCCGGTTACCCGTACCAGCTCAACGATCCCGCTTACCGGAAAAACGCCACTCGGGACGCAACAGCGACGTTAAAAGCGTGGCTGCAGGAGCACAGGAAAAACCCCTATCCCACTAAAGGAGAGAAGATCATGCTGGCCATCATCACCAAAATGACCCTCACGCAAGTGTCCACCTGGTTCGCCAATGCACGACGGAGACTCAAGAAGGAGAACAAGATGACCTGGGCACCGCGGAATAAAAGTGAAGACGAAGACGAAGATGACGGAGATGGAGAGAGAAAAGACGAGCGCACGGATAAAAACATGGACAACAGCGAAGCGTCAGCTGAGGACGAAGGCATCAGTTTGCACGTCGATGCCCTGACAGACCACTCGTGCTCGGTGGAGTCGGACGGGGAGAAGGTCACGTGTCGGACCGGAGACCTTGTTTGCGATTCTGGAGCTGAAATCCAGGACAAATGCGAGGCGACGGATCTCGGGGAGGAAAGGCAGCGAGGCGCGTCACCCAAACCGGTGACCTCTTCTCCTCTGACCGGGGTGGAGGCGCCTCTATTGACCCATCATCACCGGGAGAACAGCACCAACAAAACATGCCTGGACGGTCAAAACCAAACCGTCAAGCCTAAGCTGTGGTCATTAGCAGAGATCGCCACTTCGGACCCCAAGCAGCAGAACTGTCCCCCGGGTGTCGGCCTTCTGACCTCCAGCGCGCCCGGCGCGTCCCCGGCGGGCGCGGTTTACCCCGCCACCTCCATACTAGGAAGACCTCTTTATTACACTTCTCCGTTTTATAGTAATTACACAAACTATGGCAACTTCAGCCCGCTTCAGGGCCAGGGGATACTGCGCTACAACTCCGCCGCAGAGGGACTCCTTCATAAACAGACTGGAGAGCCGCTAATAAAGACTAATCCAAACCAGACTGAAGCTCACTTCAGGGCCTCCAATGCAGAATCCAAAAAAGACCCCAGCGAGGTTTTCACAGTAAGATCCCAATCTTACCTGTCGAGTTAAGACGAGGAAGATCTTCCAAGTAGGTGTCACAATTGCTTTGAACAAAGCGAACAAGCCATcaccccttctctctctctctctctctctctctctctctctctctctccctctctctctctctctctctctctctctctctctctctctctctctccccaagCTGTTTTAAACTAACATTTGCTCCTTATACGCGGATCCTCTTTTGTGTGCCACTGTACACCCACGGACTACAGAGCACCTGCCtatacaataacaacaacaacactgcgATTGCGGGACAGAAACGCAAAGACAAGACAGGACAAGAGAAAGAAGAGCGAGTTTATAAGGCACAATAGCCAGTCTGCTTTGGACGAACTGCTGATTTATTGATGAAGTACTTTATCCCAACACATGTGACTTTTCCATGAGGAAACTTATTTCTCAGGATCCTAATAGTAGCTTCATTGCCACCAGTTGTAAACACGCGTgggacatttattattattaattattattattatagacctCCTATGAGACTTTATATGTGCTATAGAGGTGTGAAGTGTAAATGAGATCTCGGGACTGGTATAAACTTGACTAAGAGTGGAAtacatttgatatttatttttgtaatgccTATAATTTATGCAAGTTGTATTGCAATGGTTGCTGAacattgttttgtaaataaattatgatgggtttttattttaaaaaagccgAAGTTACACAATGTTGTTAACAAGGAGACTTTTACTAATTTATATCTCTCGTTGTAAATAAAAATGCGCTAGTCTGCACTGGCACAACACTG
>TCONS_00020409
CGCCCGGCGCGTCCCCGGCGGGCGCGGTTTACCCCGCCACCTCCATACTAGGAAGACCTCTTTATTACACTTCTCCGTTTTATAGTAATTACACAAACTATGGCAACTTCAGCCCGCTTCAGGGCCAGGGGATACTGCGCTACAACTCCGCCGCAGAGGGACTCCTTCATAAACAGACTGGAGAGCCGCTAATAAAGACTAATCCAAACCAGACTGAAGCTCACTTCAGGGCCTCCAATGCAGAATCCAAAAAAGACCCCAGCGAGGTTTTCACAGTAAGATCCCAATCTTACCTGTCGAGTTAAGACGAGGAAGATCTTCCAAGTAAGTCGCTAATTTGAGCATTTCAGtgctgattattattattctgtatgctTCTGAAGGCCACGTCCTCATATTTGACACCTGTCAACATACGCTATAAATAATGCTGAGATGTTTTATCCAAatattggatttattttttatttttttgtaattaaatttattttacgaTTTT
>TCONS_00020410
ATTACCCATTATCTGTTATCCACCCCGGTCCCGTGTAATTGTGCATTCTGATAATTGCGTAGAGGATTAATCGTTGTTTATTggcttaattattattagtattatatttcTGGATACACTTTAGAATGGCGATCATTAATGACATTAACTTTATAAAAACGCAGAATGGATCATTGGTTAATTTGcatttgaattgttttattattattattattattattcatcctacattatttttgttttaaattaagctatttatttttaaagtgtttgcaaagcaaaaacacaaatacaagaACATTTGACTGACCCCGAATGTTATTTTTGAAGGGCTCTCCGTATGACGCGCACACTACGGGAATGGCAGGAGCCATAAGTTATCACCCGTACGGGAGTCCCGGTTACCCGTACCAGCTCAACGATCCCGCTTACCGGAAAAACGCCACTCGGGACGCAACAGCGACGTTAAAAGCGTGGCTGCAGGAGCACAGGAAAAACCCCTATCCCACTAAAGGAGAGAAGATCATGCTGGCCATCATCACCAAAATGACCCTCACGCAAGTGTCCACCTGGTTCGCCAATGCACGACGGAGACTCAAGAAGGAGAACAAGATGACCTGGGCACCGCGGAATAAAAGTGAAGACGAAGACGAAGATGACGGAGATGGAGAGAGAAAAGACGAGCGCACGGATAAAAACATGGACAACAGCGAAGCGTCAGCTGAGGACGAAGGCATCAGTTTGCACGTCGATGCCCTGACAGACCACTCGTGCTCGGTGGAGTCGGACGGGGAGAAGGTCACGTGTCGGACCGGAGACCTTGTTTGCGATTCTGGAGCTGAAATCCAGGACAAATGCGAGGCGACGGATCTCGGGGAGGAAAGGCAGCGAGGCGCGTCACCCAAACCGGTGACCTCTTCTCCTCTGACCGGGGTGGAGGCGCCTCTATTGACCCATCATCACCGGGA

Function


symbol description
irx2a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within pronephric nephron tubule epithelial cell differentiation and retina morphogenesis in camera-type eye. Predicted to be active in nucleus. Is expressed in several structures, including basal plate midbrain region; nervous system; otic vesicle; pectoral fin bud; and pronephric tubule. Orthologous to human IRX2 (iroquois homeobox 2).

GO:

id name namespace
GO:0048468 cell development biological_process
GO:0035778 pronephric nephron tubule epithelial cell differentiation biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0030182 neuron differentiation biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0060042 retina morphogenesis in camera-type eye biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific molecular_function
GO:0003677 DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1446 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within pronephric nephron tubule epithelial cell differentiation and retina morphogenesis in camera-type eye. Predicted to be active in nucleus. Is expressed in several structures, including basal plate midbrain region; nervous system; otic vesicle; pectoral fin bud; and pronephric tubule. Orthologous to human IRX2 (iroquois homeobox 2).

Ensembl:

ensembl_id ENSDARG00000001785

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00020407 False 6520 mRNA 0.41 3 555746 563732
TCONS_00020408 False 2295 mRNA 0.50 5 558688 563235
TCONS_00020409 False 499 mRNA 0.43 2 559669 560574
TCONS_00020410 True 968 lncRNA 0.47 2 560712 562186

Neighbor


gene id symbol gene type direction distance location
XLOC_010366 NA coding downstream 3119 551682 ~ 552627 (-)
XLOC_010365 irx4a coding downstream 172082 378766 ~ 383664 (-)
XLOC_010364 NA coding downstream 188602 354846 ~ 367144 (-)
XLOC_010363 NA coding downstream 201966 346263 ~ 353780 (-)
XLOC_010362 NA coding downstream 242193 302755 ~ 313553 (-)
XLOC_010368 NA coding upstream 640410 1204142 ~ 1218570 (-)
XLOC_010369 NA coding upstream 787239 1350971 ~ 1353006 (-)
XLOC_010370 sim1a coding upstream 901892 1465624 ~ 1503023 (-)
XLOC_010371 ascc3 coding upstream 940548 1504280 ~ 1757521 (-)
XLOC_010372 NA coding upstream 1384293 1948025 ~ 1949069 (-)
XLOC_010626 CR392024.2 misc upstream 20331380 20895112 ~ 20895175 (-)
XLOC_010359 NA non-coding downstream 316473 227820 ~ 239273 (-)
XLOC_010378 CU929110.1 non-coding upstream 2171944 2735676 ~ 2735799 (-)
XLOC_010380 NA non-coding upstream 2245985 2809717 ~ 2812008 (-)

Expression



Co-expression Network