XLOC_010383 (csf3r)


Basic Information

Item Value
gene id XLOC_010383
gene name csf3r
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 3103182 ~ 3127749 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020428
CTTCGGTTTGTGCTTGTGGTTCAGGATGGCATAAAGGACATGCCACAGAAACACAGCAGTGACGCTTTCCTCAGAGCAAAGAAATCTTTCTCAGAACTGCAGCTAGACAGGATCTTtatcaactctttttttttttttttctttttttttaccagaCCTCGCTGGGCACAAACTACACAAGATGTCGGGATTTTTAATGTAACATCAACAACCTACAGATAGATGCCTTTAAAAGACATTACCTCATCATAACCATGGCATCCGTCTCGCTTGTGCTTCTGCTGTGGATGTATATTTATGTTGTGATAAaagTGACTGGAGCATCATCGTGTGGGAATGTCTACACGCCTGCGCCTGTGGTTTTGGCTGGATCTCCGGTTTCTGTGTCCTGCTCCATCGAGGAAGACTGCCCCCTGACCAAAGGCAAAGTGTTTTACGTGCAGTGGAGGATCGACGGCCAGGTTGTCCCAAGAAATTACACCAATCAGGAGAGTAACATGACATACAGTGTGCTCATACCTCGCCTTCAAGACACAAGCGCAAGCATACTCTGTCTTGTGTGTGTTCAGGAGGACTGCCAGATTGTGGATGGAGTGGAAGTTAAAAATGGAAATCCGCCAGTTCCTCATAACCTGAGCTGTGCTTTGACTTTAGTGAAAATGCCCAGCCTCCGGTGTGACTGGAATCCTGTTCAGGAAATAGCAAATCTTCCTACCAACTATACTCTGCATTTATTTAGGGCCAAGTCACAAAAGGTTTATGCGGTCCCACCCGGGCAGCACTTCTACGTGGTTCCACGGGACGCATACGGCTATTTTACTGAGCTGGAGATTTCTGTGACAGCAGCGAATGTCTTTGGAAACACAACCACTGATCCTCTGAAACTCACCCCTTTGAACACAGtGAAGTTTGATCCTCCAAGTATTACCAGGATTGAAGCTCACAGGTATGGCTGTTTAAAATACAGCTGGAGTCTTTCGGAGACTCAGAAATGGCTGCAGTTGACCTTCATTGTGCAGTTAAGATTGAAAACCGTGAACAACCAGCCAAACAAAGACCTGGTTTATACCTCCAGGCAGTTACAGCTAAATCCGATTGAAGTGTGTAGCCTCCTCCATTGGACAGATTACAGAAGCACAGTGAGAGTGAAATATTATGCAACTAGTGAATGGAGTGAATGGAGTGACCCAAAAACTGCTACAACACTTAATAAGGCTCCAGCAGGCCGTCTGGACACTTGGCTTAAAGTGAACAATCAGACCGCACAACTCTACTGGAAGCCCTCACAGCAGTTCCGTGCCAATGGCCAGAATTTATCATACAGCGTGGACTCAAAGGACACTAAAAAGAGACTGTGTGTTACAACAGAAACCTACTGCTTTTTCAGTCTCACCAAGTGGGATAAAAAGATCTCCCTGAGAGCCAGGAATGAAGTGGGATTCTCTGATCATAATGAAGTACCAGTAGCAGTGCACAGGAACAAAGGCTTGGAGCCTGTGTCTAACTTCAGCGTTCATCCTCAATCCAACACGTCTCTGCATGTGATCTGGAAAAGCCCAGCGTTCTCCAATGTCACTTCATATGTGCTGGAGTGGAGATCTCTGTGCGGGACCACAGCAGCTCCACTGTCCTTCACACTGATTCACAAAAACAAGAGCAATACTACACTCACAGGATTAGAGCCTTCCAAGCCCTACGAGATCTCGATTTATCCCAGATACGTGAAGGGGATCGGACGTCCTGTGACTGTACTGGCTTACAGCAGTGAGAAAGCACCCTCTGATGCTCCAGAGCTGAATTATGAGGAGATCAGTCGTTCACACCTCAAATTTCACTGGGGCCAAATCCCCCTCGAAAAGAGAAATGGGATCATCCAAGGATATAGGTTTTACTTCTGGCACAATAAGAACGAAATCAAAGAGATAATGACTACGGAGACCAGCGTTGAGGTGAAGGATCTTCAACCACACACTAAATATCATGCCCTTTTATCCATTTGTACCAAGGGCGGATGTGTTAACGGATCATTTTCGACCCTGACAACTGAACGTTTGGatgGAATTGAGATGGTGATATTTgttatcccagcatgcattggtGCATCTCTCCTCGTCATCATTATTGTGTTTACCTGTTTTGGGAAACAAGAACGGGTGAAGATGTGTTTGTGGCCTATAATTCCCGATCCGGCCAACAGCAGTATTAAGAGGTGGACGACTACAGACTCACTACAGGGCTTGCCTGCATTTAAAGAAGACAAGGACCCAGTGCTGGTGTATCTGTCCCACCTGAGTCTCCTCGATATGACTGAGAAAGAGCCTTTTAAGAGCGGCTACGTGAAGGAGAACCAGTGGCCAGACGATCTGAACATCCACGCTGATACTCAGAGCTGCGACCTGGAGCTGGAGCGGGAATCTGTGCCGTACGCCACTGTACTTTTCAGCACTCCGTATCAGATCAATTCCTCCAATCCTCCAGCTTATGTGCGCTCTGAGTCCACACAGCCGCTGTTAGCAGGAGACGAGCCGGGCAGTCCTCCACCGCCATATGAGAACGTGCCCAGAGGTGGCGCTGTTTCTGCACTGAACCGCTTCTCTGCATTCTCTCAGTCCACTCAAAGCGAGGAGAGCGACGAACTCTGGGAGGAATTTCCCATGCTCAGATCTTTGGAGGTCAATCACATCTAA

Function

symbol description
csf3r Enables molecular sequestering activity. Acts upstream of or within hemopoiesis and positive regulation of hematopoietic progenitor cell differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including heart; hematopoietic system; immune system; myeloid cell; and pleuroperitoneal region. Used to study neutropenia and severe congenital neutropenia. Human ortholog(s) of this gene implicated in hematologic cancer (multiple) and severe congenital neutropenia (multiple). Orthologous to human CSF3R (colony stimulating factor 3 receptor).

GO:

id name namespace
GO:0030099 myeloid cell differentiation biological_process
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:1901532 regulation of hematopoietic progenitor cell differentiation biological_process
GO:1901534 positive regulation of hematopoietic progenitor cell differentiation biological_process
GO:0030223 neutrophil differentiation biological_process
GO:0030224 monocyte differentiation biological_process
GO:0030225 macrophage differentiation biological_process
GO:0060216 definitive hemopoiesis biological_process
GO:0030851 granulocyte differentiation biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0009897 external side of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043235 receptor complex cellular_component
GO:0004896 cytokine receptor activity molecular_function
GO:0019955 cytokine binding molecular_function
GO:0051916 granulocyte colony-stimulating factor binding molecular_function

KEGG:

id description
ko04630 JAK-STAT signaling pathway
ko04151 PI3K-Akt signaling pathway
ko04060 Cytokine-cytokine receptor interaction
ko04640 Hematopoietic cell lineage
ko05200 Pathways in cancer
ko04050 Cytokine receptors
ko04090 CD molecules

ZFIN:

id description
ZDB-GENE-080104-4 Enables molecular sequestering activity. Acts upstream of or within hemopoiesis and positive regulation of hematopoietic progenitor cell differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including heart; hematopoietic system; immune system; myeloid cell; and pleuroperitoneal region. Used to study neutropenia and severe congenital neutropenia. Human ortholog(s) of this gene implicated in hematologic cancer (multiple) and severe congenital neutropenia (multiple). Orthologous to human CSF3R (colony stimulating factor 3 receptor).

Ensembl:

ensembl_id ENSDARG00000045959

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020428 True 2687 mRNA 0.47 16 3103182 3127749

Neighbor

gene id symbol gene type direction distance location
XLOC_010382 cdcp1a coding downstream 232660 2847565 ~ 2870522 (-)
XLOC_010381 acot22 coding downstream 285012 2814233 ~ 2818170 (-)
XLOC_010380 NA coding downstream 291174 2809717 ~ 2812008 (-)
XLOC_010379 tgfb2 coding downstream 295655 2745006 ~ 2807527 (-)
XLOC_010378 CU929110.1 coding downstream 367383 2735676 ~ 2735799 (-)
XLOC_010384 NA coding upstream 220257 3348006 ~ 3348709 (-)
XLOC_010385 GRIK3 coding upstream 335978 3463727 ~ 3678976 (-)
XLOC_010386 NA coding upstream 657125 3784874 ~ 3796633 (-)
XLOC_010387 si:ch211-175f12.2 coding upstream 883218 4010967 ~ 4031386 (-)
XLOC_010388 NA coding upstream 1051287 4179036 ~ 4179967 (-)
XLOC_010626 CR392024.2 misc upstream 17767363 20895112 ~ 20895175 (-)
XLOC_010372 NA non-coding downstream 1154113 1948025 ~ 1949069 (-)
XLOC_010369 NA non-coding downstream 1750176 1350971 ~ 1353006 (-)
XLOC_010368 NA non-coding downstream 1884612 1204142 ~ 1218570 (-)
XLOC_010390 CU469524.1 non-coding upstream 1082728 4210477 ~ 4211935 (-)
XLOC_010391 CU469524.2 non-coding upstream 1106978 4234727 ~ 4267736 (-)

Expression


Co-expression Network