XLOC_010449 (grb10b)


Basic Information

Item Value
gene id XLOC_010449
gene name grb10b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 8364085 ~ 8520474 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020524
GTCTTTAGATACTGACAGCGTCCAGCgcgcacacacagtcacacacatacacatttacagTGAATAAGACACCGTTCATCTCCGCTAAAGAGAGACGCTTTTCCTCATCTATCTGAGGTGGATGTGATATCCGAGAGAGACACTAACAGAACGTGTATCATGGCTGTGGCCGGATGTCCGGATTATTTTCTACACCATCCAAATTACAAGGATAATGTAGATCGAGCTGCCAATCACAGACAAGCAGACCTGATTGGACCAAGTTTTCAGCAGTCAGCCAGTCACAATTCACCCAGCCATCAAGAGGATGACGTGGATCTGGAGGCtctggtgaatgacatgaactCTTCTTTGGAGAGTCTGTACACATCATGCAGTGTGCAATCCGAGTCCACTCCTCTTCTGCACAACGGCCAGCCACACCGACCCTCCGCCTACCACACACACGCTCAGCCAATCTCCCCACACCAGAGACTGCGGCGGTCCCAGCCCATGAACATCCTCGCTGTCAGAAGACTTCAGGAAGAGGCACAACAGTACCGGACGTCTTCACTGCCTGCCATCCCAAACCCCTTCCCGGAGCTCTGCAGTCCTGCCAGTTCCCCAACGCTCAGCTCTGGCTCCTTACCTCAGTGTCAGCCCTCAGACAAATATATTATAAAAATATTCAGCGAGGACGGGATGGGAAAGGTGGTGGAGATCCCAGCCGACATGACGGCGCGAGACCTGTGCCAGTTTCTCGTCTATAAAAACCATTGTGTGGACGATAACAGTTGGGCGCTTGTGGAGCATCATCCAGCCCTGGGACTCGAGAGATGTTTAGAAGACCATGAACTGGTTGTCCAAGTGCAGACGTCAATGATCAGCGAGAGTAAATTTCTCTTCAGGAAGAACTATGCCAAATATGAATTCTTTAAAAATCCTTTGAACTTCTTCCCTGAGCAAATGATTGCCTGGTGTCAGGAGACCAATGGGACCATCCCCCCATCTCAGCTCTTGCAgAACTTCTTGAACTCCAGCAGTTGTCCTGAGATCCAGGGATATTTGTATGTGAAAGAGATGGGCAGGAAATCGTGGAAGaaactgtatgtgtttttaagacGGTCAGGGTTGTATTTTTCGACGAAAGGAACGTCAAAGGAGCCCAGGCATTTACAGCTACTAGCAGACCTGGAGGACAGCAATGTCTTTACAGTGATAACAGGGAGAAAGCTGCACAGTGCACCGACTGACTTTGAATTCTGCATAAAACCGAACAAAGTAAGGAATGAAGTGAAGGAACTAAGGATGTTGTGTGCAGAGGACGAACAGAGCAGAACATGCTGGATGACAGCCTTCAGACTCTTTAAGTATGGAATTTTACTCTATCAAAATTACAAGATCCACCAGCAGAGAAAAACGTTGCTTTCACACTTCTCAGCGCCTGTGAGGAGTGTTTCAGAGAGCTCTCTGGTTGCCATGGATTTCTCAGGGAGGATAGGCAGAGTGATCGACAATCCTGTGGAGGCACAGAGTGCTGCCATGGAGGAGGGACATGCCTGGAGAaagaaaagcCAGCAGCGTATGAATATTTTAGGAAGCCCCAGTTCTTTACACCCCTCATCATTAAGCGGAGTTATCCACAGAACTCAGCTGTGGTTTCACGGTCGTATTTCACGGGAAGAATCCCACAAGCTGATCCATCAGCAGGGCAGAGTGGATGGAATGTTTCTCCTGAGGGACAGCCAGAGCAATCCTAAGGCGTTTGTACTTACACTGTGTCACCACCAGaaaatcaaacattttcaaatattGCTGTGTGAAGAAGATGGTCAAATGTTCTTGAGTCTCGATGACGGCGCCGTCAAATTCACAGACCTAATCCAGTTGGTGGAGTTTTACACGCTCAACAGAGGAGTTCTGCCTTGCAAACTGAAACACCCCTGCACCACTGTGGCCTTATGACCTCCATATGCCTGATTTCGCCTAAAGACAAACATTCAGACGACGTGTGCTGTGGTGTAATGCTGTGCTGCTTGGCTGGAGAAAAGCACACTTTGAGAGCAAGtcaaggagaaagagagagagggaaaaaaaattgaTACACAAACAGGGCCGGCAAGAATTAAGGAAATTAAGCTTGTGTGTTAGATGAACCTCTCAGCCACCCGCACACTCAACCGTGGCCAGGGCAGGTTCTCAGGACAATCATCCAGAGGAAGCCTTCAGGATCCGCCTTCAGGTCTTAATCGTGCAGATGTGATAGTGGTTTGGAAATGGCCAGCAAAACACTTATCAATCAcgtttgattttattttgcacTCATGAACCAGGAACAACCAAGCTATAACAATTgttactttcaaaaaaaaaaaaaagtcaagcagATTCTAGAATGTGGACAACAGATTGGTGGTTTCAGTACTGTGAAAAGACACTGCCGACCGTTGAATTTTTCGCTTTCTGTCACTTTCATCCATAATTCAATTATTTAGATGTAcacttgctttctttttttaaaatgctcGTCGTTTTGAGCACAAAACTCTCATGTTTTGGGTCTTGTTTAGTTTCTGCTTTATCACAAAGCATAGCCTGCAGCGCTCTCTGCTGGCCATACCCAGACATGACACGTCACTCCTTCAAGGAATAGTTTACCTCAAAAATAAAACTGGGTTATTTTAGCTATTTACGAGGTTGCACCAGAACCACATAATCTTTGTTTTGTAGAACACAGGAGACATATGTATTTGACATCCAAAAATGCTGTATTTCAAGTCCGTTTTATTGAAACCTTACAGTCAACCCTACtataaaaaacagcttaaaccagcctggttttataggggttttggccatttccaggctggtttccagccatttccagcctggactaagctggtcaggctgggagaggaccagttaaaaccagcttgactagccttgccagactgggagtccagccaaaaccagctacatGTATGTCCAGCTCATATCAGGCTGGTCATGCTGCCCCCATAGCAAAAAATCTCTGGCCCATatctggcccacaccatcagcatttgcttgggccacatgccgcagtgaattacggaaCATGACTGAACCAAGTCTGGCTTCCGTACAAGAGGCAAAcatagaccatatctgggccaagactctgccaagttaataacccataactgggcctgaactgggccagatatgttggtgtgtcatgactgcaatgttttttataaacCTATGAAGCATTTCGCTTTACGGCTGTGCTTTTTCTTAAAGCGACCCGAttgatatataattatttttttattttttttatttttttactcaaaactaacttaaattatttaaaaagtgggtcaagatagaccaaacttacgtggcccacgtatacatttttaacatctgggccaaatactacatttgatatctggcccaagtcttgagtGCCGCCTGTAAGCTGGTGCCACCTTGGCCAATGTATGCCAGTGCCAGACAAATGCTTGCTTTGctagctttatgccaaatctggaccAGAATTATTGGCTACCTAAgtggttttagttggtcattttccagcctgaccagctaagaccaggctgaaaatggctggaaactagcctggaaatggccaaaacccctccaaaaccaggctggctgaccagctaaaaccagccaaccagcttaggctgatTCAGGCTGTTTTGTTCCGCAGGGAagaccattttattttagttCTAAAAGGTCTGAGTAAGGACTAAAGGCCTCATCACAACAAAGGGTGGTAATTATaaagataaatattaaaaaaagacttCAGAACACAGTTATAATGCTAAAGATGTACATAAATTATATCATCAAGAATGACTTTCAGAACTTCTAAAACAGTGATAGCAGTCAGAATTCATAAACAAAATTTAAAGGTCTCAAAGGTGTTCTCACATTGTGGAGAAGCACACCCTGCTTGATGTTAATCCCTCTTTTCAAAGATTATTTAAAGATAACGTCCATTTTGAAAACAACATGGGAGCAGTGTTAAATAGCATGGAGGCTATGCAAGCCAGGCTAGCAAATTgaagtataaaataaaagtacCCTAAATATCCATTGCTAAATTTTGCATCTTTGTTGCCACTTTTAAAAATcctgagaaaaaaatatacagtttattTTCCTGCGATTTCTAAACTCTTCGTTTAATTTGAACAGCACactgaggacatctgctggttaTTTGGCGGTAATGCAAAAAGAAAAGTTTAAGGCAAAAGTAAGCAGATCGCTCTTGTTTGCTTGGATGGACACAAATATAGTCATTTTGGTTCTACCTATATGTAGTTATCTTCCTTAGTGTGAACAGGCCTTAAGACCTAAAGAAGGTTGGATTCAAAAGAGTTGGAGACCATGAAAATTTAAGTTTAGAGTACTAAAAAAATGTGAtagctttgtttaaaaaatgtctaaCAAACACAGTTCACATTTACCCTCATTATAAAAAAGATGGTTTCAATGGTGATAATGAAGAACAACAaggatatacattttatttttgaggcAACTATTCCTTTAAACACGAGTGCAAGCAAAACATGGCCTGACATTCCCACCAGATCCTATAGGAACGGTGCCTTGAACAGAGGAGTCTGTTGAGTTCAGTGAAATAAAAACCACTAAACCCTCTGGGAACTCCGCTGTGGGTCGCAGTCTTTCAGGAGCTAGATCAACAAACTGGAATCTCTTTAACTGCTGTCATCTTCAGTCCCAGCTCCAGTCCATTTGGTTGTTGactttctatttttttctctctccatgtTTCGGAAGATTGTTTCAAGGACAGCACACTGTGAAGCCCGGGCTAAGAACACCCAAGGAACAATGGGGTTCGAATTTCTAATCTGCCTTGTCCATGGTAGCAGTAGGTACAATGgatttgtaaagattttttttttgtacttatgACACAATGTAAAGAAAGAGCCATGTTTAGTATTGTGTTCTGCTAGATTGAGAGGGCATAGCCACCATGTCTACAAGTTCACCCAAGAGACCAGTACATAGATAAATGCAAATGACGCAATCGATAATAAGCATTGCttcaacaaatttatttatttatctggatTTGATTACTTGAAATTTAGTttcgtttttagtttttttttttttttctcagcgcTGTTGATACTATTGttccacatttttttgtgaatttttttggACCTCAGTTAACAAGACCCCCgttctaaaacattttaagactaaTTTTCATCAATATCCTAGTGTAGAATCACAGTCTTCATGGACCTTATTTGTGGTAGACATGTAGTGCACTCTCTTCAATGGATTTTAATCTTACATTAATTGCTGTCAGCtcataatacaattttatataaacacctgaagaaaaaaaagaaaatccagttAACATTGTGACTTATTAAACCAGTGGCGTAGCAAGTCAGTGACcggatacattttttaaaaatatttgacgGGACATTTAAAACATATCAAACTATACAATTAAAATACACTCTACCCAACAACTTTTTTACAAGCAGACTGGGActtcatatttcatatatttatatatatatatat
>TCONS_00020525
GGAACAGAGGCAAGTTGTCTGCCAAGCTGGAAACAGTGCCATCTGCATGCTCTGTTCTGCGCCAAAGCTAgtctgagagagagaaagagaagaaggAAGATTGTGACAGGTAGTACACGCTGAGCCACTGACAGGAAGAAGCATCTGCAAAGCAGAGGAactgctttttcttttctttcttttttttgtttgctcgTTTTTTCTATCTTGTGGAGTTGTGGAGACATTCGGGGAGCGGGTCCGTCTCTCAGTTTGTGGAGGAGGACACAGGCTGCTGGGGAAAATGCCATCGTGTTCTCCTGACTGTTGCCTGCTCAGGCCTGGGGAGATTATAAAAATATTCAGCGAGGACGGGATGGGAAAGGTGGTGGAGATCCCAGCCGACATGACGGCGCGAGACCTGTGCCAGTTTCTCGTCTATAAAAACCATTGTGTGGACGATAACAGTTGGGCGCTTGTGGAGCATCATCCAGCCCTGGGACTCGAGAGATGTTTAGAAGACCATGAACTGGTTGTCCAAGTGCAGACGTCAATGATCAGCGAGAGTAAATTTCTCTTCAGGAAGAACTATGCCAAATATGAATTCTTTAAAAATCCTTTGAACTTCTTCCCTGAGCAAATGATTGCCTGGTGTCAGGAGACCAATGGGACCATCCCCCCATCTCAGCTCTTGCAgAACTTCTTGAACTCCAGCAGTTGTCCTGAGATCCAGGGATATTTGTATGTGAAAGAGATGGGCAGGAAATCGTGGAAGaaactgtatgtgtttttaagacGGTCAGGGTTGTATTTTTCGACGAAAGGAACGTCAAAGGAGCCCAGGCATTTACAGCTACTAGCAGACCTGGAGGACAGCAATGTCTTTACAGTGATAACAGGGAGAAAGCTGCACAGTGCACCGACTGACTTTGAATTCTGCATAAAACCGAACAAAGTAAGGAATGAAGTGAAGGAACTAAGGATGTTGTGTGCAGAGGACGAACAGAGCAGAACATGCTGGATGACAGCCTTCAGACTCTTTAAGTATGGAATTTTACTCTATCAAAATTACAAGATCCACCAGCAGAGAAAAACGTTGCTTTCACACTTCTCAGCGCCTGTGAGGAGTGTTTCAGAGAGCTCTCTGGTTGCCATGGATTTCTCAGGGAGGATAGGCAGAGTGATCGACAATCCTGTGGAGGCACAGAGTGCTGCCATGGAGGAGGGACATGCCTGGAGAGTgagttacaataatattttttggtcatttaagttacatgttaaaaaaacactccactttttttggaaataagcTCATTTTTTTCAACTACCCTAGAGTATAACAGTATAAAAGGACatttgccctgctgaaaaatccagcttaaaccagcctaggctggttg

Function

symbol description
grb10b Predicted to enable insulin receptor binding activity. Predicted to be involved in insulin receptor signaling pathway; negative regulation of Wnt signaling pathway; and negative regulation of insulin receptor signaling pathway. Predicted to act upstream of or within signal transduction. Orthologous to human GRB10 (growth factor receptor bound protein 10).

GO:

id name namespace
GO:0030178 negative regulation of Wnt signaling pathway biological_process
GO:0046627 negative regulation of insulin receptor signaling pathway biological_process
GO:0008286 insulin receptor signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0005158 insulin receptor binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-091020-12 Predicted to enable insulin receptor binding activity. Predicted to be involved in insulin receptor signaling pathway; negative regulation of Wnt signaling pathway; and negative regulation of insulin receptor signaling pathway. Predicted to act upstream of or within signal transduction. Orthologous to human GRB10 (growth factor receptor bound protein 10).

Ensembl:

ensembl_id ENSDARG00000035308

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020524 False 5586 mRNA 0.42 17 8364085 8520474
TCONS_00020525 True 1382 processed_transcript 0.46 9 8372265 8395559

Neighbor

gene id symbol gene type direction distance location
XLOC_010448 ddc coding downstream 21336 8298542 ~ 8342749 (-)
XLOC_010447 CR478208.1 coding downstream 75638 8287771 ~ 8288447 (-)
XLOC_010446 entpd3 coding downstream 83200 8258203 ~ 8280885 (-)
XLOC_010445 gask1a coding downstream 112100 8188188 ~ 8251985 (-)
XLOC_010444 NA coding downstream 221773 8140712 ~ 8142312 (-)
XLOC_010451 cobl coding upstream 9298 8529772 ~ 8663552 (-)
XLOC_010452 NA coding upstream 148507 8668981 ~ 8679462 (-)
XLOC_010453 triob coding upstream 231341 8751815 ~ 8927425 (-)
XLOC_010454 adcy2a coding upstream 755215 9275689 ~ 9383629 (-)
XLOC_010455 CR394537.1 coding upstream 781605 9302079 ~ 9302194 (-)
XLOC_010626 CR392024.2 misc upstream 12374638 20895112 ~ 20895175 (-)
XLOC_010442 CU856516.1 non-coding downstream 379184 7968020 ~ 7984901 (-)
XLOC_010441 NA non-coding downstream 482808 7834219 ~ 7881277 (-)
XLOC_010438 BX511173.1 non-coding downstream 667869 7693881 ~ 7696216 (-)
XLOC_010458 FO704756.1 non-coding upstream 1044029 9564503 ~ 9566371 (-)
XLOC_010461 NA non-coding upstream 1238702 9759176 ~ 9761753 (-)
XLOC_010466 NA non-coding upstream 1492511 10012985 ~ 10013605 (-)

Expression


Co-expression Network