XLOC_010463 (grhl2a)


Basic Information

Item Value
gene id XLOC_010463
gene name grhl2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 9807263 ~ 9830451 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020546
AAACGCTTTTCCGCTTGATCCTGAATGTTTGGCTCCTGTCCTTTGTGCGGTACAGACGGAGGATGCTGTAATGAGAGTCGGATGCGAGAAGTTGTTTGACCTGTAGtccgagtttttttttttcatccagcCTTTCCCTGCTACTCACCTGCCGTATCTTCACCGACCTGAAAGTCCAGTTTCACTGTGGGAGCCCAGCAAACTGCACATGGCTCAGGAGGAGAATAAGCGTCTGGTGGTGGTGGTCCCTAATGAAATGACCGTTCCATCACGCCGTGCCTTCACAAGTGAAGACGAGGCATGGAAGTCTTACTTGGAGAATCCACTGACTGCTGCCACCAAGGCCATGATGAGCATTAATGGAGATGAGGACAGTGTGGCTGCCCTGGGAATCCTTTATGATTACTATAAGGTTCCTAAAGAGAAGAGGCTCCTGCCAGTGCACAAACTTCCAGAAGATCATGAAAAAAGTCGGATCAGTCAAGATGGCGTCGAGTCCGCGGAAAATCGTATTCATGTCCTGAAGTCACTTCCGGTCAACCTGTCACTGAATCCTGATTCAGAAAACAAGCAAGACCTGTTCGGCACAGTGCCTGCCGAGGACGGTGTAGTGGCCACTGTAAAGCCAGAGGTTTATGCTCAGTCATTCTCCAGCCATCACCAGCAGCTTCATTATCACCGTACGCCCTACCATCCGCATTTACAGGATTCAGTGAGCGTCAGCCATGATAGATACATGAAGGACGATCAGTGCAGCACACCAGACAGCACCTTTGAGGACTCCTATCCTGAGGACCCTATGAGGTACAGGGTGCCTACTACGCCTGCGGCTGAAGATTTCACACATGAGCAAGCAGGGTTAAACATGTTCCAGTATAATATTGAAGCAAGCCGTTCTGTCCGTGAGAAGGCTGCCGATGGGCCGATGGTGTATCTGAACAAGGGCCAGTTCTATGGCATCACACTCAGTGAGACCGGGGCCAACAAGGGCCTTCGTCATCCCATCAGTAAAGTGCGGACTGTAGTGATGGTGGTGTTCGGACAGGAGAAGTGTCGGGATGAGCAGTTGAAACATTGGAACTACTGGCACACCCGTCAACACACTGCCAAACAGAGAGTCCTTGACATAGCTGACTATAAAGAGAGTTTCAACACCATTGGCAACATCGAGGAAATCGCTTATAATGCAGTGTCATTCACTTGGGATGTCAATGAGGAGGCTAAGGTTTTCATTACTGTGAACTGTCTGAGCACCGATTTCTCCTCTCAGAAGGGAGTTAAAGGTCTTCCACTTATGATCCAGATTGACACATACAGTTACAATAACAGGAGCAACAGACCCATCCATAGAGCCTACGCTCAGATCAAGGTCTTCTGTGACAAGGGAGCCGAGCGAAAAATACGTGATGAGGAGAAAAAGCAACTTCGGAAGAAGGTTAAAGGTCAGACTGTTGGCGGGCACGGTCAGGATGgTAAGAGAGGAAATTTGGCCAGTTTACCTCCAAAGAGGCCAGACATTACGCTTTTCAAAGCTATGACAGACTTGGAGTCCCAGCCTGTGCTCTTCATCCCCGATGTCCATTTGAACAATCTCCAGAGAGCCGGCCAGGTGTTCAGTTTTGGTGTTGAAGAAATGGAGAATGACGGGGTGGCCGTGAAGAGACCGTTCGGGACATCAGAGGCTGATTCTCCACCTACCAAATACAGCAGAGAGGAGAGGAAAGTCCTGCTGTACGTAAGGAGAGAAGCTGATGAGGTTTTTGATGCACTGATGCTGAGGTCTCCAACGCTGAAAAGTTTACTTGAAGCTATATCGGGCAAATATTCTGTTCCTGTGGAGAAAATGACTAAAATCTATAAGAAAAGCAAGAAAGGTATCCTGGTCAACATGGATGACAACATCATCGAGCACTACTGCAACGAGGACACTTTTATTCTGGCCATTGACAACCATGCGGACTGTTTCCGGGTCACTCTTACTGAAATTTAATGGTTTGTGGAGGACTTGGGACCCTGCAGCAGTGCACAAATCATTTTGTGCATCAGTGATTTTATTGTAGGCACTGCATTAGAAGAGGAAAACGCTTCCAGACATGTCTGACTGGGAATGCACTCCAGTGGATCTGCTGGTACTAATTAACTTGTTTAAATAAACACTATGATGGACTACACAAAATCAGA

Function

symbol description
grhl2a Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; neural tube development; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in olfactory placode; otic placode; otic vesicle; pronephric duct; and pronephros. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4. Orthologous to human GRHL2 (grainyhead like transcription factor 2).

GO:

id name namespace
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0021915 neural tube development biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0007420 brain development biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050913-123 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; neural tube development; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in olfactory placode; otic placode; otic vesicle; pronephric duct; and pronephros. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4. Orthologous to human GRHL2 (grainyhead like transcription factor 2).

Ensembl:

ensembl_id ENSDARG00000058342

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020546 True 2181 mRNA 0.48 16 9807263 9830451

Neighbor

gene id symbol gene type direction distance location
XLOC_010462 tapbpl coding downstream 4265 9787383 ~ 9802998 (-)
XLOC_010461 NA coding downstream 45510 9759176 ~ 9761753 (-)
XLOC_010460 COLEC10 coding downstream 112441 9680908 ~ 9694822 (-)
XLOC_010459 mal2 coding downstream 131281 9672126 ~ 9675982 (-)
XLOC_010458 FO704756.1 coding downstream 240892 9564503 ~ 9566371 (-)
XLOC_010464 ncalda coding upstream 2805 9833256 ~ 9897769 (-)
XLOC_010465 id4 coding upstream 147407 9977858 ~ 9980402 (-)
XLOC_010466 NA coding upstream 182534 10012985 ~ 10013605 (-)
XLOC_010467 cep76 coding upstream 195445 10025896 ~ 10053049 (-)
XLOC_010468 ptpn2a coding upstream 225041 10055492 ~ 10071887 (-)
XLOC_010626 CR392024.2 misc upstream 11064661 20895112 ~ 20895175 (-)
XLOC_010455 CR394537.1 non-coding downstream 505069 9302079 ~ 9302194 (-)
XLOC_010452 NA non-coding downstream 1127801 8668981 ~ 8679462 (-)
XLOC_010450 CU062417.1 non-coding downstream 1328254 8478880 ~ 8479009 (-)
XLOC_010472 NA non-coding upstream 590719 10421170 ~ 10429893 (-)
XLOC_010473 NA non-coding upstream 595296 10425747 ~ 10428540 (-)
XLOC_010477 NA non-coding upstream 1019255 10849706 ~ 10859614 (-)
XLOC_010478 CU468227.1 non-coding upstream 1085839 10916290 ~ 10916404 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000016_09384358_09401878 GRHL2A coding CI01000016 null 9384162 ~ 9401878 (-)