XLOC_010488 (cd4-1)


Basic Information

Item Value
gene id XLOC_010488
gene name cd4-1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 11911897 ~ 11946139 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020583
tagacacacacacacctctacaTAACTGCCAATCAGACGGAGGGGAGGCGTCAGCGAAGGTTAAATAGAAATATTTTGGCCTGTAAGTGAACACATCCGCTGACACGACTCTGAAGACAAGCGATACGTAACGTTGATCATCCGCTCTGGCTCTGATCTGAGGACCGAAAGATGCTCGGTTTGATTCTAATACCGCTGTTCATTACAGTACTTAAAGCACAAGAAAGCCATGAAGTCATTTACGCACAGGTAGGAGGGACTGTCACCCTACCCAGAGAAAAGATTGAACGAAAATATAGCAATATTAAAACACAAGATATTTATGTGAACTGGTTCCTTGAGAGTACTCTGACAATCAACAGGAACCCGCAGAGTAGCAGCAGTAAGGGGACAAACACACGCGTCTCTCTATCAGCAGATTTCTCTCTTCAGATCTCACCAGTTGAAGAGTCTGATTTTGTCATTTGGCGCTGTGTACAACATGTATTAGCAGGAAATTACGAAAAGACCTACAAACTGTACAAAGTCTCAATTCCCAAAGTGCCTGCTCTGCTGGTTGGTGGTCGCCTGTCTCTGAAATATGTAAAGGATGTTAGTTCAGTTAATCCCAGTGTAACATGgatttcacctaaaaatgaaggcTGTCAGGAAAATAAGAATACTAAAGATACAGTTTTAGTCCCCAGTGTGTCCACATGTCATAATGGTGTTTGGACATGCCAGTTGAAGtatggaaataaaaaaactgaggCAACAACTACTGTTTCTGTTATAGACCTTGCCCCTTCTCCAGCAGATCCCATTTATACCTCTATCTCTCAATCCTCGACAGTCAGCATTCCCTGTGCTTTGTCTTCTGCAATTCCCTGGTCGGTCTTAAATGAAACTCTTCAGGGTGGGAGCTGGAGCTTCACTCCTCTCAGTGAACCTCGGTCGCCTTTATCTCTCCTCACCCTCAATGTTGGTTCGGTGGTCCGATGGGATCTCGCAAACGGCGCAAACTTCACTGACGGCAAAAGAGTCATAACTAACCACAACCTGTCCATTCAGAATCTGCCTGTAAAAGAAACAATCAGAGGGGTTTACAAATGCAGTCTGAAATTCAACACCAAGACCATCAGCCGTGAAGTCAAGGTGGAGGTTTTGAAGGTTTCCCCTTCTGGAATTTTGAAAGTATTCGAAGGCACAAGGTTGAATGTGACATGCTCATTAGGACATATGAACACCGCTGGCCTTGAGGTGAAATGGGCATGTGCATCAAACTGTCCTCCTTTCAATCACAAGTCTCCGCCTCATCTGTCAGTTCTGTCCTTCCCTAATATCAGGATGCAGGACAAAGGCCTGGTCAAATGTGAACTCTGGAAAAATAGCCAAAAGCTGACATCAGCTCAGCTATATTTAAGAGTTGAGAAAGCTCCAGTGGACATCTGGCTGTGTGTTGCCATCGGGAGTGGAGTGGTGGTCTTCATCTTGCTTGTTGCATTCGCCATCATATACATCCGCAGACACAAACAGATGATGATGTACAGACGACGCAAGACCAGATTCTGCTGCTGTAACAATAACAAACAGCCAAAGGGATTCTACAAGACCTGAGGATCTTCTGCTTTTCAATTTTATTACTGATTTTCTAAATCAGAGTTAATGTACAGTTCTTTGCACAATGTTTGCCATTTCAGAAATGACTGTGTTCAGTGCGCAGATGAGGATGCTggtatttctttattattgtcaaatacaataataaaagtacacacatacaatattattttattatgtaaatattttgataataGCATGATATGatgtcattaaataaaataatttgctaAATTTTGTAATCATTGATTTTGTCTGTAGGTTTTGTTATATTCACATTTAGTGCCTTGTTATATAGTGTTGATATTTTTTATGTTCTCCTGTTTACTTACTGTGTGCTCTTTAGCATTTGTAAATGATCTTTTTCCTCTGATTGCTTGTATTTCTTTATTTGAGAACAGCAACaggttgataaaataaaataaaattagtttgaaACAAAAA
>TCONS_00020584
ACCTCTCAGGCCAATCAGACGGAGGGGAGGCGTCAGCGAAGGTTAAATAGAAATATTTTGGCCTGTAAGTGAACACATCCGCTGACACGACTCTGAAGACAAGCGATACGTAACGTTGATCATCCGCTCTGGCTCTGATCTGAGGACCGAAAGATGCTCGGTTTGATTCTAATACCGCTGTTCATTACAGTACTTAAAGCACAAGAAAGCCATGAAGTCATTTACGCACAGGTAGGAGGGACTGTCACCCTACCCAGAGAAAAGATTGAACGAAAATATAGCAATATTAAAACACAAGATATTTATGTGAACTGGTTCCTTGAGAGTACTCTGACAATCAACAGGAACCCGCAGAGTAGCAGCAGTAAGGGGACAAACACACGCGTCTCTCTATCAGCAGATTTCTCTCTTCAGATCTCACCAGTTGAAGAGTCTGATTTTGTCATTTGGCGCTGTGTACAACATGTATTAGCAGGAAATTACGAAAAGACCTACAAACTGTACAAAGTCTCAATTCCCAAAGTGCCTGCTCTGCTGGTTGGTGGTCGCCTGTCTCTGAAATATGTAAAGGATGTTAGTTCAGTTAATCCCAGTGTAACATGgatttcacctaaaaatgaaggcTGTCAGGAAAATAAGAATACTAAAGATACAGTTTTAGTCCCCAGTGTGTCCACATGTCATAATGGTGTTTGGACATGCCAGTTGAAGtatggaaataaaaaaactgaggCAACAACTACTGTTTCTGTTATAGACCTTGCCCCTTCTCCAGCAGATCCCATTTATACCTCTATCTCTCAATCCTCGACAGTCAGCATTCCCTGTGCTTTGTCTTCTGCAATTCCCTGGTCGGTCTTAAATGAAACTCTTCAGGGTGGGAGCTGGAGCTTCACTCCTCTCAGTGAACCTCGGTCGCCTTTATCTCTCCTCACCCTCAATGTTGGTTCGGTGGTCCGATGGGATCTCGCAAACGGCGCAAACTTCACTGACGGCAAAAGAGTCATAACTAACCACAACCTGTCCATTCAGAATCTGCCTGTAAAAGAAACAATCAGAGGGGTTTACAAATGCAGTCTGAAATTCAACACCAAGACCATCAGCCGTGAAGTCAAGGTGGAGGTTTTGAAGGTTTCCCCTTCTGGAATTTTGAAAGTATTCGAAGGCACAAGGTTGAATGTGACATGCTCATTAGGACATATGAACACCGCTGGCCTTGAGGTGAAATGGGCATGTGCATCAAACTGTCCTCCTTTCAATCACAAGTCTCCGCCTCATCTGTCAGTTCTGTCCTTCCCTAATATCAGGATGCAGGACAAAGGCCTGGTCAAATGTGAACTCTGGAAAAATAGCCAAAAGCTGACATCAGCTCAGCTATATTTAAGAGTTGAGAAAGCTCCAGTGGACATCTGGCTGTGTGTTGCCATCGGGAGTGGAGTGGTGGTCTTCATCTTGCTTGTTGCATTCGCCATCATATACATCCGCAGACACAAACAGATGATGATGTACAGACGACGCAAGACCAGATTCTGCTGCTGTAACAATAACAAACAGCCAAAGGGATTCTACAAGACCTGAGGATCTTCTGCTTTTCAATTTTATTACTGATTTTCTAAATCAGAGTTAATGTACAGTTCTTTGCACAATGTTTGCCATTTCAGAAATGACTGTGTTCAGTGCGCAGATGAGGATGCTggtatttctttattattgtcaaatacaataataaaagtacacacatacaatattattttattatgtaaatattttgataataGCATGATATGatgtcattaaataaaataatttgctaAATTTTGTAATCATTGATTTTGTCTGTAGGTTTTGTTATATTCACATTTAGTGCCTTGTTATATAGTGTTGATATTTTTTATGTTCTCCTGTTTACTTACTGTGTGCTCTTTAGCATTTGTAAATGATCTTTTTCCTCTGATTGCTTGTATTTCTTTATTTGAGAACAGCAACaggttgataaaataaaataaaattagtttgaaA
>TCONS_00020585
ATGCTCGGTTTGATTCTAATACCGCTGTTCATTACAGTACTTAAAGCACAAGAAAGCCATGAAGTCATTTACGCACAGGTAGGAGGGACTGTCACCCTACCCAGAGAAAAGATTGAACGAAAATATAGCAATATTAAAACACAAGATATTTATGTGAACTGGTTCCTTGAGAGTACTCTGACAATCAACAGGAACCCGCAGAGTAGCAGCAGTAAGGGGACAAACACACGCGTCTCTCTATCAGCAGATTTCTCTCTTCAGATCTCACCAGTTGAAGAGTCTGATTTTGTCATTTGGCGCTGTGTACAACATGTATTAGCAGGAAATTACGAAAAGACCTACAAACTGTACAAAGTCTCAATTCCCAAAGTGCCTGCTCTGCTGGTTGGTGGTCGCCTGTCTCTGAAATATGTAAAGGATGTTAGTTCAGTTAATCCCAGTGTAACATGgatttcacctaaaaatgaaggcTGTCAGGAAAATAAGAATACTAAAGATACAGTTTTAGTCCCCAGTGTGTCCACATGTCATAATGGTGTTTGGACATGCCAGTTGAAGtatggaaataaaaaaactgaggCAACAACTACTGTTTCTGTTATAGACCTTGCCCCTTCTCCAGCAGATCCCATTTATACCTCTATCTCTCAATCCTCGACAGTCAGCATTCCCTGTGCTTTGTCTTCTGCAATTCCCTGGTCGGTCTTAAATGAAACTCTTCAGGGTGGGAGCTGGAGCTTCACTCCTCTCAGTGAACCTCGGTCGCCTTTATCTCTCCTCACCCTCAATGTTGGTTCGGTGGTCCGATGGGATCTCGCAAACGGCGCAAACTTCACTGACGGCAAAAGAGTCATAACTAACCACAACCTGTCCATTCAGAATCTGCCTGTAAAAGAAACAATCAGAGGGGTTTACAAATGCAGTCTGAAATTCAACACCAAGACCATCAGCCGTGAAGTCAAGGTGGAGGTTTTGAAGGTTTCCCCTTCTGGAATTTTGAAAGTATTCGAAGGCACAAGGTTGAATGTGACATGCTCATTAGGACATATGAACACCGCTGGCCTTGAGGTGAAATGGGCATGTGCATCAAACTGTCCTCCTTTCAATCACAAGTCTCCGCCTCATCTGTCAGTTCTGTCCTTCCCTAATATCAGGATGCAGGACAAAGGCCTGGTCAAATGTGAACTCTGGAAAAATAGCCAAAAGCTGACATCAGCTCAGCTATATTTAAGAGTTGAGAAAGCTCCAGTGGACATCTGGCTGTGTGTTGCCATCGGGAGTGGAGTGGTGGTCTTCATCTTGCTTGTTGCATTCGCCATCATATACATCCGCAGACACAAACAGATGATGATGTACAGACGACGCAAGACCAGATTCTGCTGCTGTAACAATAACAAACAGCCAAAGGGATTCTACAAGACCTGAGGATCTTCTGCTTTTCAATTTTATTACTGATTTTCTAAATCAGAGTTAATGTACAGTTCTTTGCACAATGTTTGCCATTTCAGAAATGACTGTGTTCAGTGCGCAGATGAGGATGCTggtatttctttattattgtcaaatacaataataaaagtacacacatacaatattattttattatgtaaatattttgataataGCATGATATGatgtcattaaataaaataatttgctaAATTTTGTAATCATTGATTTTGTCTGTAGGTTTTGTTATATTCACATTTAGTGCCTTGTTATATAGTGTTGATATTTTTTATGTTCTCCTGTTTACTTACTGTGTGCTCTTTAGCATTTGTAAATGATCTTTTTCCTCTGATTGCTTGTATTTCTTTATTTGAGAACAGCAACaggttgataaaataaaataaaattagtttg

Function

symbol description
cd4-1 Predicted to enable MHC class II protein binding activity and protein tyrosine kinase binding activity. Predicted to be involved in T cell activation; interleukin-15-mediated signaling pathway; and positive regulation of ERK1 and ERK2 cascade. Predicted to act upstream of or within adaptive immune response. Located in cell surface. Is expressed in blood; digestive system; gill; immune system; and muscle. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).

GO:

id name namespace
GO:0042110 T cell activation biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:0035723 interleukin-15-mediated signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0045121 membrane raft cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0009986 cell surface cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:1990782 protein tyrosine kinase binding molecular_function
GO:0042289 MHC class II protein binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-100922-280 Predicted to enable MHC class II protein binding activity and protein tyrosine kinase binding activity. Predicted to be involved in T cell activation; interleukin-15-mediated signaling pathway; and positive regulation of ERK1 and ERK2 cascade. Predicted to act upstream of or within adaptive immune response. Located in cell surface. Is expressed in blood; digestive system; gill; immune system; and muscle. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).

Ensembl:

ensembl_id ENSDARG00000070668

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020583 False 2043 mRNA 0.41 11 11911897 11946139
TCONS_00020584 False 2019 mRNA 0.41 10 11911903 11932923
TCONS_00020585 True 1863 mRNA 0.40 9 11911906 11928774

Neighbor

gene id symbol gene type direction distance location
XLOC_010487 cxcr3.1 coding downstream 52588 11853212 ~ 11859309 (-)
XLOC_010486 cnfn coding downstream 112903 11790640 ~ 11798994 (-)
XLOC_010485 tlr21 coding downstream 122789 11785967 ~ 11789108 (-)
XLOC_010484 zgc:158701 coding downstream 132236 11760602 ~ 11779661 (-)
XLOC_010483 NA coding downstream 272425 11597384 ~ 11639472 (-)
XLOC_010489 si:ch73-296e2.3 coding upstream 14278 11960417 ~ 11963804 (-)
XLOC_010490 usp5 coding upstream 19232 11965371 ~ 11986321 (-)
XLOC_010491 NA coding upstream 46427 11992566 ~ 12005084 (-)
XLOC_010492 CU467865.1 coding upstream 65935 12012074 ~ 12012188 (-)
XLOC_010493 si:ch211-69g19.2 coding upstream 105871 12052010 ~ 12060782 (-)
XLOC_010626 CR392024.2 misc upstream 8948973 20895112 ~ 20895175 (-)
XLOC_010482 BX005242.1 non-coding downstream 373076 11437869 ~ 11538821 (-)
XLOC_010480 NA non-coding downstream 900245 10980052 ~ 11011652 (-)
XLOC_010479 NA non-coding downstream 992463 10917584 ~ 10919434 (-)
XLOC_010478 CU468227.1 non-coding downstream 995493 10916290 ~ 10916404 (-)
XLOC_010497 CR388102.3 non-coding upstream 293268 12239407 ~ 12239460 (-)
XLOC_010498 CR388102.2 non-coding upstream 301723 12247862 ~ 12247920 (-)
XLOC_010499 CR388102.4 non-coding upstream 304129 12250268 ~ 12250323 (-)

Expression


Co-expression Network