XLOC_001052 (knl1)


Basic Information

Item Value
gene id XLOC_001052
gene name knl1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 11086957 ~ 11104805 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001694
TACTTGGAGTTGAGCAAGAGGAGCAAAAGGAAGAAATTGCCAAGCCTGTAGAGAAGAGGAGAAATTCACGTAGAGTGAGTTTTGCCACTACGAATAATGTGCGAGTCTTTACCAATGAGGCAAAGAATGAATCTCCTGTTCTGGGATCCATACAAAACTTACATGAAGAGCGGCCTGATGAAAAGATCCTGCGTTTTGCGGATGAGGGAAGTCACCAAATTAAAGGCCTGGAAACTTTGTTGCACACTCCTCTTTATCTAACCCAGAATAAAGAAAATTTCTTCTCTGATCCGGTCTTACAAGATGACTATGTAGATAGAACAATACTACTTGGTGAAGATACTGGATACATGGATATTACTCACAGTCACACTATCACATTTGATAAGGATTATGAAATCAAAGAGGAGGCAAACCAGGATGTTAGCTTCAAAGTGGCTCAGACTGTCTGTGGTGATTCGAATATTCCAAGTCAGAAAGCAGACAAGAAAAATGTTTCAATGGACTCAGACTTCAGTGCTTTTCTCGCAAGTATGCACTTACCCACTGTAAATACTGTTAAGCTCCAAAAATCAGAAAACGAGCTCAATAATGCCTCCGGTCCAGCGAATACAAGCATTTCAGAAATTGATAAGGAAAATTTCTTGCCATCTTTTTTGACGAAACCACAACCAAGCAGCAAGTGTCAGCTACTACAACCCCGAGGACTTCAACGCAGACGTTCTCGAGTTTCATTCATTGAAAATGACGAAAGTGGGTCAACAATGGGTCGCACTGTTGTAACAGAAAACATTGATAGTGCACAGTCTTTTACACCCTCAGTTCCTAAAAACCCTAGAAGTGTTCCCATCATGACATCTGCTTTTCCAGATGTGTCAGATGACATGGAGTTCACTGCTCCAGTCAATGCTAAAGTTACAGGAAATATCACTTGCGGTGTCCAGGCTGCTCTGGATCAGAATAGATCACATTATTTCTCTGAAGAAGACAATGCAATGGAGATGACGGGGGTATCTGATATATCCGTTCGAAATAAAGACTACACGGTGAATATGATGGAACAAAGTCAGCCTTCAGTTCCTAAAGTAAGAAGGATGTCCTCCTTGACTGTCATTGGAAATGGAGAGATAACAGATCAAAGCAATGCTGGTTATTTTCAGGGCAATCTATCAGTAGCCCAAACAACAGATTGTGATAATATGGAAATGACTGAAGCTTTAGATGTTTCTCTTCAAGACAAAGAGAAAGCTTTGTTTCCCAAAGTAAGCAGGAGGTCCACATTTGATGTTTTCGGAAATGGAGACATAGTGCAAAACAAATCTAACAGCAGCTTAATGGTTCCTCCTGCAAATTCCGATGATATGGAGATGACTGAGGTTATTGATCTTGAATCCAAACCATCAGTTGAAAACAAACTGCTTCACGGCTCAAGGAAGAGTTTGCCGCTGACATCTATATCCAGAAAGGTTCAAGAAGATAAGCATACAAGCATTATGAAGGAGAACGGTCTGCATCCCATTCCTACTGTAAACAGGAAGACCTGCTTTAATGTTGCTGAAAATGGAATCGTACTGGATTACAATAAATCAGGCCACCTCTCCATAGCCCAAGACGACAATTCTGGCGATATGGAAATCACAGAGTGTCGAACTGATTTTCTCGAAATCAAACAATCAACTGAAAACAAGTCATTTGGTAGCTTCTGGAAGAATTTGCCTTCTTCATCTTCATCCAAGACAGTTGGAGAAGACGAGCATACAGGCAGCGTCAAAAAGGAAGCTCTGTGTTCAACGTCTAGTGTAAACAAGATGCCCTGCTTTAATTCAAATTCTGATGATATGGAAATGACACAGTGTCACACTGTTTTTCTTCAACCTAAACATGTCAGTGGGGATGAATCATTAAGTGTTCCAATAAAAAATGGACCTCTTACATCACTATCTGGAACTGAAGGCGGGGATGAGATGGACATGACTCAAGTACCCACTGGGCGTATAATACTAAATGGTCATTCTTCCTATAAAAAGGAAAAAGGTGAAAGCATTCTGATACCTGCTTCAGCTACATCACCTGTGCATAATAAGAGTGACTATATGGACTTGACATGTGTACAAAGTACTTTTGCAGAGACTTCTCTCCCATGTCCAGACGAAATGGAATTTACAGCATGCGTCGCTGACATTGCCTCAAACCGAACAGGAAGAACTGTGGATATCACAGATATAAGAGCGCCATTCTCTGCCAATCAAACCGTCATCGTGGTTGAACCTATGGAGATGACTGAAGTACATATGGCACCATTCAGTGAGCGAAAGCATAAAGCTTTTATGACTCGAAGAAAGTCAGGAGCAAGGATGATGTCCTTGATGTGCAATTCTGGAAACACTGAAGCTGATAACTGTCAATTTGATTTCTCCAACTCTGATAACATGGACATGACACAATGTCAGACTGCAGTGCTGGAGGCTGAAACTTCCAAGAGGGCCACACCATTCAACAAATCAAGGAGGAATTTGAACAGTGCATCCTGCAGTCCTGATGGTATGGAGATAACTCAGCCACTCACTGGCAAAATAGTGTTAAAAAGCTTTGCATCTAATGAGGAAAGTAAGCATCAGCAAAATCCTTTGCCTGAAGCCCAAAGTTGTCAAATGCAGAACGAGTCTCAGTGTATGGAACTGACATGTCAAGCCAGTGCATCAAATCTAGCCATTCCCTATGTTGATGATGAAATGGAGCTAACAGGATGCAATACGATTGCAATGGACTCAAAAAGCACATTGGCATCAAGTGCTGCGGAGATCAAAGTGAATGAAAGTGCACTTTGGGCATCAacaactgtttctaaatgcacAGTGTCAAGTGAAGAACAAAATGAGGTGAGTGAAGCTGCCAACTGTGCTAATAGCAGTGTTTTCCCCTCAAAGGATCTTTTTGATCTTGGTGGAAAAAGCGTTAAATGCAGCAACATGGAGACAACATCCTACATACTACCCGATATGCAAGTGGACAAAAATTGTGAAACGGCTCTCCCAAGCAATGTGATGGCGAACGATGAAGATGATATGCAAGTCACAAAGCCCCTAACATTGCCTATTGAAATTGAGCAAACGTTTTCATTTAACCAGAACGAAGAACCCAATACATCCTCCGGTTTTAGAAATGACAAAGAGGGTCATGCTCATAATGCTAAAGCAAGACGAAGAAGTTTAGCAGACTTTCAAATGGAGCTTCATAACATGTCACAACGTATCCTCGAAGAGCCAAATTTAATGACAGTAAGCGCAACTGCGCCTCTGCCTTCTTGCACACTCTCAGAGAACGTGCAGAATGAAATGGGAAGTTCTGCCGAGCCTGCTTCAAATGTCACACCTGTTGTCAAGCAGAAAAATAATTCTGCGCAAAGTCAGAAGACCACACCTTTTAGTCTTAACAAAAAATCCTTTTCCTCAAGGATGTCATTGTGTGGGGTTGTTCCAAAGCTACCAAAACGAGCTACAGCTTTCACTCCCAACAAATCCCTGCCCATAAGTTTAAATGGTTTACCGTGTCTCGAGCTAGAGAAACATTTTGAAGTTGCTGAACAAAAAAGCAATCAAACAGTCGATATTAACGATGAAGAGTTCCCTGAAATGAGCAGTGAAGAAGACCTCTCGGGGAGTCTTGAAAATTGGCCAGTTAGTAAGCAAGATGAACTGGATGAATCTTTGGCTGTACCCATGAAAGAAGAGTTTTTAATAGACGATGTCTTCGAGTCAGGCACAAGCCCTTCTTTTAAAAGGCCACATCCAGAGGAAGAACCTATTACACCAGAACAAACCAAGAAGACCTGTGTTTCTGACATGGGGTCTGACTGTCATGAAGCTGCCGTACAGTGGGAAGGTAATTTTACAAGGCATGCCGCTCAGAATCCCAAGGCAAAGACAATTGAAGATACAGGAGTCTCTGAATCCACTCTCAGGCACTCGCAGTTTGACTCTCATATGGACGGCATGCAGGATAATCTATTTGATTTTAATAAGAAACTTGAGGACGGAAGCATCACAGTGAACGAGTTTCTTAGCCACTTTGGCATCAAATTCGTCATCCACAGATCTAGACCAAGTGCTCTGCCTGTCAGGTGTGGCGCTGGTGAGACACGCACCATCGAAGATTTGCTGAAAGAAAAATACATAAGCCACCCCAAGCAGAGAGTATATGAGCAAGACTGTAAGAACATTACAGAAATAGTGGAGAGACTTAAAGAACAAATGTCTGCACAAGAGAAATCCCTGAGAAGCATCAATGGAGCCCTTCAACAAGAGATATGTACTCTCTCTGAAGAACAGTTAAAAAGCTTTGGATCCAAGTTGAAGGAGCGAAGGGCTTATTTTGGGAAGAAAAGCAAAGCAGTTTCTCATGAAATGAAAGGAGTGTTGTACTCTGAGCTCATAAAAACAACACAGGATGCAAAACTGAGCCTGATATCTAAAATCAAAGAGACAGATGAAATGATTGAAGACTTGGATGGCTGCATTAAAGATTTAGAAACCGATCTTGCGTCAGTTGATGCCATGATCACAGGGGATCGTCTTGATCTTCCTCAAGCAGGACCAGCCTTAAAAGCCAAGGAAGAAGATTTGCATCGACTCAATTCAGCTGTCACTTTCAAAGAGAGGGAAATTGGTGAGCTGGAGATTCAGCTGAAGACTTTGGAGAGCCAACAGGAGAAGCTGCAAGGGGAATCCAGTAGCCTTAAGAGTCATCTGGCAACtttaaacagTTTGAACGAGTGGCGTCTTGAAGCGACAGATGAAACAGGGGCTTTGTTTTCCTTCCTTCATAAAACTGTGCATCTGCAGGTGAACCTTCAAACACCTGCTGGGAAGGAATGGATGACTGAGGATGTGGAGAGAAATGTAGATGTAGTCTTCCAGTTGCAGCTGGATGGACAAAAGTCAGAATGTCATGCAAGCATGATTCATAATTTACTCGCAACGAAGATTGAGTCTCAAAGTCATTGGAAACAGAGGTACACAACAACCAGACATATACCAGAGCTCTTGCATACCATGAGTTTGGTGGTGGGTCGTCTCAGGCTTTTGGGTGAGGAGATTCACCGGTTGAAGAAGTGGGGAGGTTTGAGGCTTAGAATACTGAAAATCACTTGTACGGATACACGAGTTCATGTCATCTTCTCAAGTCTGAAATCCTTTGAAAAGTTTGAGCTGAGTCTGACGGTCACTCCAGACTATCCCTTTGGACCACTTCACATACAGGACTTCAAAAACCACATGGGAAACACAAGGTTGGATCAGCTCGAGGAGATCATATCGTCAGTTAAACCAGCCAAGAACTATCTGTCAAAAATCCTCAAGAAGATCCACGATGACCTCCTGTGCTAGGACCTCAGGTCTTATTGTTTACTCTGTTCtgtcttttaaatgtttgtaCATGTTTGTATTATCCCAAAATAAATGTGGCCGTAAACTACAAGTTTGCCGGcattctttaaat

Function

symbol description
knl1 Predicted to be involved in attachment of spindle microtubules to kinetochore and protein localization to kinetochore. Predicted to act upstream of or within cell division. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly and primary autosomal recessive microcephaly 4. Orthologous to human KNL1 (kinetochore scaffold 1).

GO:

id name namespace
GO:0034501 protein localization to kinetochore biological_process
GO:0008608 attachment of spindle microtubules to kinetochore biological_process
GO:0000777 condensed chromosome kinetochore cellular_component
GO:0005634 nucleus cellular_component

KEGG:

id description
ko01009 Protein phosphatases and associated proteins
ko03036 Chromosome and associated proteins

ZFIN:

id description
ZDB-GENE-030131-5437 Predicted to be involved in attachment of spindle microtubules to kinetochore and protein localization to kinetochore. Predicted to act upstream of or within cell division. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly and primary autosomal recessive microcephaly 4. Orthologous to human KNL1 (kinetochore scaffold 1).

Ensembl:

ensembl_id ENSDARG00000070239

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001694 True 5496 mRNA 0.42 23 11086957 11104805

Neighbor

gene id symbol gene type direction distance location
XLOC_001048 dmd coding downstream 11552 10824351 ~ 11075405 (-)
XLOC_001051 BX004756.1 coding downstream 24310 11062524 ~ 11062647 (-)
XLOC_001050 NA coding downstream 149142 10936724 ~ 10937815 (-)
XLOC_001049 BX323090.1 coding downstream 216716 10870117 ~ 10870241 (-)
XLOC_001047 crfb15 coding downstream 265373 10809604 ~ 10821584 (-)
XLOC_001053 sdk1b coding upstream 19941 11124746 ~ 11519934 (-)
XLOC_001054 NA coding upstream 365985 11470790 ~ 11517353 (-)
XLOC_001055 si:dkey-26i13.7 coding upstream 490993 11595798 ~ 11596829 (-)
XLOC_001056 si:dkey-26i13.6 coding upstream 501205 11606010 ~ 11607062 (-)
XLOC_001057 si:dkey-26i13.5 coding upstream 510468 11615273 ~ 11616295 (-)
XLOC_001045 NA non-coding downstream 346516 10739165 ~ 10740441 (-)
XLOC_001044 NA non-coding downstream 404808 10671852 ~ 10682149 (-)
XLOC_001061 NA non-coding upstream 588352 11693157 ~ 11695392 (-)
XLOC_001062 NA non-coding upstream 606738 11711543 ~ 11714363 (-)
XLOC_001067 NA non-coding upstream 960351 12065156 ~ 12068877 (-)
XLOC_001068 NA non-coding upstream 1000842 12105647 ~ 12126625 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000300_01963369_01973641 KNL1, CASC5 coding CI01000300 null 1963284 ~ 1974476 (-)